CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LT854705	Lactobacillus zymae strain ACA-DC 3411 chromosome I	10 crisprs	cas1,cas2,csn2,cas14j,cas3,DEDDh,DinG,csa3,WYL	0	13	28	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LT854705_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT854705_1

185878-186309

TypeII

Consensus_repeat	Method
GTTTTAGATGAGTGGTAAATCTAGAAGGTCAAAAGC	PILER-CR
GTTTTAGATGAGTGGTAAATCTA	CRISPRCasFinder
GTTTTAGATGAGTGGTAAATCTAGAAGGTCAAAAGC	CRT

6 spacers

csn2,cas2,cas1,cas9,cas14j

The CRISPR arrays of NZ_LT854705_1

>merge|NZ_LT854705|1|185878-186309|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGATGAGTGGTAAATCTAGAAGGTCAAAAGCACAACCTTAAATAAACCAGCAAGGTTCTTAGTTTTAGATGAGTGGTAAATCTAGAAGGTCAAAAGCACCGGTTCAAGTAAGGAGGTGGCGGCATGAGTTTTAGATGAGTGGTAAATCTAGAAGGTCAAAAGCGGCACCCAGTACGCATGCGTCTGGACAGGGGTTTTAGATGAGTGGTAAATCTAGAAGGTCAAAAGCCCAAAAAAGGGGCGATTGCTCTCTTTGCTAGTTTTAGATGAGTGGTAAATCTAGAAGGTCAAAAGCCGGCGCAATGGCTAGACAAGAACCGGGCTAGTTTTAGATGAGTGGTAAATCTAGAAGGTCAAAAGCTTGGGCCAGCTGGTCCTACGGGTGCCGACGGTTTTAGATGAGTGGTAAATCTAAATAGTTATGTAT

>NZ_LT854705|1|1|185878-186243|PILER-CR
GTTTTAGATGAGTGGTAAATCTAGAAGGTCAAAAGC	ACAACCTTAAATAAACCAGCAAGGTTCTTA
GTTTTAGATGAGTGGTAAATCTAGAAGGTCAAAAGC	ACCGGTTCAAGTAAGGAGGTGGCGGCATGA
GTTTTAGATGAGTGGTAAATCTAGAAGGTCAAAAGC	GGCACCCAGTACGCATGCGTCTGGACAGGG
GTTTTAGATGAGTGGTAAATCTAGAAGGTCAAAAGC	CCAAAAAAGGGGCGATTGCTCTCTTTGCTA
GTTTTAGATGAGTGGTAAATCTAGAAGGTCAAAAGC	CGGCGCAATGGCTAGACAAGAACCGGGCTA
GTTTTAGATGAGTGGTAAATCTAGAAGGTCAAAAGC

>NZ_LT854705|1|1|185878-186296|CRISPRCasFinder
GTTTTAGATGAGTGGTAAATCTA	GAAGGTCAAAAGCACAACCTTAAATAAACCAGCAAGGTTCTTA
GTTTTAGATGAGTGGTAAATCTA	GAAGGTCAAAAGCACCGGTTCAAGTAAGGAGGTGGCGGCATGA
GTTTTAGATGAGTGGTAAATCTA	GAAGGTCAAAAGCGGCACCCAGTACGCATGCGTCTGGACAGGG
GTTTTAGATGAGTGGTAAATCTA	GAAGGTCAAAAGCCCAAAAAAGGGGCGATTGCTCTCTTTGCTA
GTTTTAGATGAGTGGTAAATCTA	GAAGGTCAAAAGCCGGCGCAATGGCTAGACAAGAACCGGGCTA
GTTTTAGATGAGTGGTAAATCTA	GAAGGTCAAAAGCTTGGGCCAGCTGGTCCTACGGGTGCCGACG
GTTTTAGATGAGTGGTAAATCTA

>NZ_LT854705|1|1|185878-186309|CRT
GTTTTAGATGAGTGGTAAATCTAGAAGGTCAAAAGC	ACAACCTTAAATAAACCAGCAAGGTTCTTA
GTTTTAGATGAGTGGTAAATCTAGAAGGTCAAAAGC	ACCGGTTCAAGTAAGGAGGTGGCGGCATGA
GTTTTAGATGAGTGGTAAATCTAGAAGGTCAAAAGC	GGCACCCAGTACGCATGCGTCTGGACAGGG
GTTTTAGATGAGTGGTAAATCTAGAAGGTCAAAAGC	CCAAAAAAGGGGCGATTGCTCTCTTTGCTA
GTTTTAGATGAGTGGTAAATCTAGAAGGTCAAAAGC	CGGCGCAATGGCTAGACAAGAACCGGGCTA
GTTTTAGATGAGTGGTAAATCTAGAAGGTCAAAAGC	TTGGGCCAGCTGGTCCTACGGGTGCCGACG
GTTTTAGATGAGTGGTAAATCTAAATAGTTATGTAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT854705.1\|WP_057734589.1\|171836_173738_+\|bifunctional-metallophosphatase/5'-nucleotidase	unknown	unknown	gnl\|CDD\|277357
NZ_LT854705.1\|WP_157667836.1\|189023_189857_-\|IS982-family-transposase	unknown	unknown	gnl\|CDD\|372648
NZ_LT854705.1\|WP_087741344.1\|179730_183783_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	mkCas0193_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|374653
NZ_LT854705.1\|WP_087742763.1\|174128_174794_-\|aquaporin-family-protein	unknown	unknown	gnl\|CDD\|223653
NZ_LT854705.1\|WP_087741352.1\|190120_191284_+\|transposase	cas14j	-	gnl\|CDD\|223747
NZ_LT854705.1\|WP_087741339.1\|170220_171597_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|181958
NZ_LT854705.1\|WP_087741342.1\|176672_178565_+\|beta-galactosidase	unknown	unknown	gnl\|CDD\|236673
NZ_LT854705.1\|WP_087741356.1\|194212_195145_+\|pyrimidine-specific-ribonucleoside-hydrolase-RihA	unknown	unknown	gnl\|CDD\|182465
NZ_LT854705.1\|WP_087742764.1\|192098_192686_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225239
NZ_LT854705.1\|WP_087741346.1\|184874_185180_+\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0206_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|226043
NZ_LT854705.1\|WP_087741353.1\|191616_192045_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_LT854705.1\|WP_087741350.1\|187907_188885_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NZ_LT854705.1\|WP_087741345.1\|183991_184897_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_LT854705.1\|WP_157667835.1\|187439_187799_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647
NZ_LT854705.1\|WP_087741343.1\|178545_179511_+\|beta-galactosidase	unknown	unknown	gnl\|CDD\|214988
NZ_LT854705.1\|WP_087741355.1\|193414_194131_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_LT854705.1\|WP_087741354.1\|192993_193314_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_087741348.1\|186401_187325_-\|ribokinase	unknown	unknown	gnl\|CDD\|274000
NZ_LT854705.1\|WP_157667834.1\|185176_185842_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd12218_csn2_CAS-II-A	gnl\|CDD\|213411
NZ_LT854705.1\|WP_087741887.1\|175085_176102_-\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382

Protein	Function_ID	Function_description	E-value
NZ_LT854705.1\|WP_057734589.1\|171836_173738_+\|bifunctional-metallophosphatase/5'-nucleotidase	gnl\|CDD\|277357	cd07412, MPP_YhcR_N, Bacillus subtilis YhcR endonuclease and related proteins, N-terminal metallophosphatase domain. YhcR is a Bacillus subtilis sugar-nonspecific endonuclease. It cleaves endonucleolytically to yield nucleotide 3'-monophosphate products, similar to Staphylococcus aureus micrococcal nuclease. YhcR appears to be located in the cell wall, and is thought to be a substrate for a Bacillus subtilis sortase. YhcR is the major calcium-activated nuclease of B. subtilis. The N-terminal metallophosphatase domain belongs to a large superfamily of distantly related metallophosphatases (MPPs) that includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	3.19671e-86
NZ_LT854705.1\|WP_157667836.1\|189023_189857_-\|IS982-family-transposase	gnl\|CDD\|372648	pfam13612, DDE_Tnp_1_3, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contains three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	7.92081e-21
NZ_LT854705.1\|WP_087741344.1\|179730_183783_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|374653	pfam16592, Cas9_REC, REC lobe of CRISPR-associated endonuclease Cas9. The REC lobe of Cas9 - the CRISPR-associated endonuclease Cas9 - includes the REC1 and REC2 domains. REC1 forms an elongated, alpha-helical structure consisting of 25 alpha helices and two beta-sheets, whereas REC2 inserted within REC1 adopts a six-helix bundle structure. The REC lobe and the NUC lobe of Cas9 fold to present a positively charged groove at their interface which accommodates the negatively charged sgRNA:target DNA heteroduplex. CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system occurs naturally in bacteria as a defense against invasion by phages or other mobile genetic elements. Cas9 is targeted to specific genomic locations by sgRNAs or single guide RNAs, in order to complex with invading DNA in order to cleave it and render it inactive.	5.82729e-129
NZ_LT854705.1\|WP_087742763.1\|174128_174794_-\|aquaporin-family-protein	gnl\|CDD\|223653	COG0580, GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism].	1.02807e-67
NZ_LT854705.1\|WP_087741352.1\|190120_191284_+\|transposase	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	7.872e-45
NZ_LT854705.1\|WP_087741339.1\|170220_171597_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|181958	PRK09564, PRK09564, coenzyme A disulfide reductase; Reviewed.	1.61349e-94
NZ_LT854705.1\|WP_087741342.1\|176672_178565_+\|beta-galactosidase	gnl\|CDD\|236673	PRK10340, ebgA, cryptic beta-D-galactosidase subunit alpha; Reviewed.	6.08627e-163
NZ_LT854705.1\|WP_087741356.1\|194212_195145_+\|pyrimidine-specific-ribonucleoside-hydrolase-RihA	gnl\|CDD\|182465	PRK10443, rihA, ribonucleoside hydrolase 1; Provisional.	0
NZ_LT854705.1\|WP_087742764.1\|192098_192686_+\|hypothetical-protein	gnl\|CDD\|225239	COG2364, COG2364, Predicted membrane protein [Function unknown].	2.25716e-18
NZ_LT854705.1\|WP_087741346.1\|184874_185180_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	2.34415e-22
NZ_LT854705.1\|WP_087741353.1\|191616_192045_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.50878e-16
NZ_LT854705.1\|WP_087741350.1\|187907_188885_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	3.12463e-83
NZ_LT854705.1\|WP_087741345.1\|183991_184897_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.5066e-86
NZ_LT854705.1\|WP_157667835.1\|187439_187799_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	5.88965e-16
NZ_LT854705.1\|WP_087741343.1\|178545_179511_+\|beta-galactosidase	gnl\|CDD\|214988	smart01038, Bgal_small_N, Beta galactosidase small chain. This domain comprises the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.	1.61217e-96
NZ_LT854705.1\|WP_087741355.1\|193414_194131_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	3.43075e-20
NZ_LT854705.1\|WP_087741348.1\|186401_187325_-\|ribokinase	gnl\|CDD\|274000	TIGR02152, Putative_ribokinase, ribokinase. This model describes ribokinase, an enzyme catalyzing the first step in ribose catabolism. The rbsK gene encoding ribokinase typically is found with ribose transport genes. Ribokinase belongs to the carbohydrate kinase pfkB family (pfam00294). In the wide gulf between the current trusted (360 bit) and noise (100 bit) cutoffs are a number of sequences, few of which are clustered with predicted ribose transport genes but many of which are currently annotated as if having ribokinase activity. Most likely some have this function and others do not. [Energy metabolism, Sugars].	4.85499e-142
NZ_LT854705.1\|WP_157667834.1\|185176_185842_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213411	cd12218, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	6.81616e-60
NZ_LT854705.1\|WP_087741887.1\|175085_176102_-\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	8.09877e-67

>NZ_LT854705.1|WP_157667834.1|185176_185842_+|type-II-A-CRISPR-associated-protein-Csn2
MKLTYYSYAPFDVPTGRITVVDTGALNIYHDLVRGLRNDEETLHVATDEYDLKEVNQLCRWYGDPLLELDLNAVFQRKLQVQLLKVLSDQQTVQLTDQFQQLLTQILGDSYALDVPLGIPETPELAKLMKFSGLKIDGIADMGIHGILETLIKVLVELNDRHTVVLTNVSHYLQVAQFKLLSKAVADAGLPLLIIEFSEIRRQRLFADCDYHYIDSDFVLW
>NZ_LT854705.1|WP_087741346.1|184874_185180_+|CRISPR-associated-endonuclease-Cas2
MRLMVLFDLPMTTSKNRRNYRQFRKTLIQEGFFMMQYSVYVRVCADSKAARAIERRLARLVPTDGLVQTVMMTEKQYQNMHFIAGEPSQDVLNSAARTVII
>NZ_LT854705.1|WP_087741345.1|183991_184897_+|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTVVVTQHAKISLMTGNLVVQTDTDRYHIPVRDVGVLLIQTVQAVITAAALVALAEVQAKVIFTGRDGQPICTTTGDYSNAQSAVTVQEQVAWPQERMMKLWTRIVASKLQNQIRVAQFVNAPIENLQQELDQLEFNDITNREAVVARRYFPLIFGDDFSRSDLTPINAALNYGYAILLSTVDQAIGVRGYLTCLGIHHARTDNAYNLGSDLMEPFRPIIDQWVSQQKIRDFTPDIKYGLVDLLNVAMTYNGQQTILRNAIPKYVGHCLDYLSGTVGTIQVEVEIPNEVSSHALNGTV
>NZ_LT854705.1|WP_087741344.1|179730_183783_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MYKKYGIGLDIGTSSIGWSVVDEYGHIIRVKGQTGLGVRLFREGQPAADRRTFRTTRRRLGRRRWRLRLLREIFDPYIAAQDPNFFARQKASAIAPGDSRFKAVYRLFNDQTDRQFYDKYPTIYHLRQALMTEKRQFDIREIYLAVHHIVKYRGHFLTGGAAKNFKSGKLDLNTYFATINAQLAAIFMDSPVELPELDWDAVVQLLTDDQESPSDRQKALTKLLMAQGDATQKRFYTEFSKALLGLKAKLYILTGFEGDKTDQKALTLSLETLDDHQDDMTQLLGDEQRQLVELLARVQSAIQLAIIIPNGKTFSGQMVQQYQTHHDQLRLLKNYREQLTDQKHRWALKQAYTDYLANDQDQDALVKAVEKVLKQNQPLSTVGVQLQTAIDTGDFVPKQRTKANSVIPHQIHQQELDRIIEAQSVYYPWLAEENPVAAHRSYAPYKLDELVDFRVPYYVGPLVQPQADKAAKETKFAWMTRKEAQSTTPITPWNFEQEVDRNASANAFIQRMKTTDTYLLGEDVLPKNSLLYQRFEVLNELNNVRVDGKLLTIAEKQRIFQELFVDRSQASVTIAQLQANLIAHGAAKDRVEIKGLADPKRFLSSLTTYHDYAQIIPEALEQPDKRADIEKIINWSTVFEDTSIFKEKLQEIAWLTPDQRRQLSQKRYRGWGQLSDKLLTQLRDATGRSVMDLLWTEPNNFMQIIRRPEFQQAIARVNQTDLKQQDLATTINDLYTSPQNKKAIRQVLLVVADIQAAMHGVAPSWLFIEAARGPEQNPKRKLARQQQLLEAYKTSAKEIVNEAVKEKLLSAIDDHQSFEDRVVLYFQQNGLDMYTGKPLDFERLSKYHIDHIIPQSVVKDDSLDNRVLTTPEENERKGARVPGPLYASQQGRWRLLQRAGLISQRKLHHLLLRPEKLDQQATGFVARQLVETRQVIKLITNILSQQYDPEQTKLVSVKAGLSHQFRTKLNLPKLRELNDYHHAHDAYLAARIGTYLLQRYPNLERFFVYGQYQKTRFDLKRHFNFIGDMLKGKPDDAVIVKAPHSETVIWDKQDEVNRLEQLMAYKHLLVTHEVYDNHGALFDQTIYSAKNPKNKKLIPRKTTQPTELYGGYSGETTGYLAIARTVIKNKTSYQVLRVPTRLVGRLQRSSESTQRQILTDWFAPSFVSRGKQQPFEIVLPHVYLEQPVIDEIHGQAHRFGLGTNTYYHNQQQLVLPLAQQRVMIERQPDADELARVYEMICDQVTQYFPLYQMNRFKEKLLVAGPKLSELTINILKAKDGKLHLGQKAVLLRIMQGLHANPQIVDLSVIGCPKYFGMLQVKSGIKLTENAVLIHESPTGLFQRRVRLSDL
>NZ_LT854705.1|WP_087741343.1|178545_179511_+|beta-galactosidase
MANTTAKLHVVYGDGTLGLHGEGFQYIFSYERGGLESLKRNGKEWLYRVPKPTFWRATTDNDRGNHFSEKSAMWLGADLFSPCTHIEVAVNGQDITLPIAPENNRYSDHETAETVTIRFTYTTTTVPATTVVVSYTVDATGAIRVHTYFAGQAGLPELPALGLRFVMPTAAQQFSYRGLSGETYPDRMAGGQLGDYQVTGLPVTPYMVPQECGMHMATEHATVTRVITLNNADPDTEPFSLTFTQADQPFNFSCLPYTAEELENATHIEELPPLRRTVFTVFGAVRGVGGIDSWGADVEAKYHLPADRDYDFEFVIAGTQE
>NZ_LT854705.1|WP_087741342.1|176672_178565_+|beta-galactosidase
MQADLKWLDNPQTFRVNQLPAHSDHHYYRTVAEMQAHQSSFVQSLDGTWQFAFAQTPQERPVGFEQPDADHQNFGEIQVPGHIELAGYGQLHYTNTLYPWEGKLYRRPAYALGDTTGMPGMFSEGPDNTVGAYLKTFTLNPELRDHRVVIQFDGVEEAMYLWLNGHFVGYAEDSFSQSEFDLTPYLQAGENLLAVEVFKRSTAAFLEDQDFFRFSGIFRSVRLVAQPTVHVNDLTIRANVLDDLTTGDFNVTLNLNADAAQSGAQVKTILHAGQQVLLNQTVPAQAELTIRHVPVPNVHLWDHHDPYLYQLQVEVLDASGQLLEVVPYDVGFRRVELKDKVMLLNGHRLILNGVNRHEWDAKRGRSVTLADMQYDLQVFKQHHINAVRTCHYPDQIAWYSLCDRNGIYMMAENNLETHGTWQKMGAVEPSYNVPGSLPQWQGAVVDRARSNYQTFKNHPAILFWSLGNESYAGDDIAAMDQYYHDHDEGRLTHYEGVCRNRVYADRISDMESMMYDPPKAIRDYLDNDPQKPFVNCEYMHDMGNSLGGMNSYTDLIDQYPMYQGGFIWDYIDQALLVNDEVTGQPVLRYGGDFDDRHSDYEFSGDGLLFADRTPKPALQEVSYYYGKYDR
>NZ_LT854705.1|WP_087741887.1|175085_176102_-|IS30-family-transposase
MTHSQINTHKHYQQLSLSDRATIQALRATGDTATVIAQKLHRSKATISREITRGSVTQLDSKRHSHQVYLAETAQAIHDRKRDRTGHHAFLKTGRAFFKALTKELTRKPRVHSVDSFVHFYRDQGKSCPSTTTVYRYIDAGLLELDNMTLPKKLRRRVKGYKNAHKRKNKKIYGDSIELRPAAVNDRTGVGHWEGDLVKGIRSADEPALMTLTERYSRTEIIVKIPDYHADTCLKALQDTINDYGAKEFESITFDNGSEFAKLSEIVGTQIYFAHPYSPWERGTNENTNGLLREYFPKGKSLRDVTLVEVQAVQSALNHRPRRILNYLRPCDYYRRMA
>NZ_LT854705.1|WP_087742763.1|174128_174794_-|aquaporin-family-protein
MVALGNGSVANVELKGTKGYHGGWVLIGFGYGIGVMIPALMFATISGAQINPAMTIAQAVVGNFPWAEVLPYVIAQTLGAIVGQLTVVLAYKPYYDKTTDAEAILGTFSTIDAADSKLNGFLNEFIGTFLLVLGAVFMTADKLDPRADFLGLGFLVMCLVVSFGGPTGPALNPARDIGPRLLHALWPFKYKGSSQFEYSWVPIVAPIAGAIAATVLYQAFL
>NZ_LT854705.1|WP_057734589.1|171836_173738_+|bifunctional-metallophosphatase/5'-nucleotidase
MTIAHHHHKLLYSLLVPLLVAGSASTLPGLDDHSAHAAAQKVTTQTDKYSTPTSQPGFKKLAKKYKTAIPIQVLGINDLHGGLETTGTVKIGDQTYSDVGTVARLGGSLDQAQNQFKKTQHAKAANTFRVEAGDMVGASPANSTLLAHESTMHTLRAMKFQIGTLGNHEFDHGLGEYNRILKGNKPAANADSLVKAYPHQASKINLVVANVVKKSNNKIPYGYKPYTIKTVKAHGKTAKVGFIGIETTDLPHLTLLKNYQNYKILDEAKTIAKYDKVLNKKGVKAVVVMAHTGIASQDGKTAGSAVDILNKVNKLDKKNNVGLYVAGHSHQYANATVGKTHVVQAVYTGKAYNDTQGYINPKTGKFMHLESHVYPVLPAKANPKAKTNAKVAAIVKDADKRVAPKVNAVIGKAATNEPITGRNNNSKTMENAAGELVVDAQRYEAQKNGTKPDFAMTNNGGVRADLAVANNGDITWGAAVAVQPFGNILQVVEMTGQQIKDALNQQYDENQAFYLQISGLKYTYTDNNDAKQPYKVVDIKKDDGTPVSMTATYRVVINDFLHGGGDNFYAFKDTPIKASIGSDTDVFVQYFKDMAAANTPVKAPTLDRKVYQPAGSVVATSTQPVNQVQVALG
>NZ_LT854705.1|WP_087741339.1|170220_171597_+|FAD-dependent-oxidoreductase
MSKERIVIVGASHGGHQSILELLSRYNDVDITLFEAGDFISFMSCGMELYLENSVTDVNDVRNFSADDFPQPNVHILDRHEVTKINADAKTVTVVDHATNQTTDQPYDKLILSSGVTPKSLPVPGADLDNVFLMRGKDWALKIKEKLADPAVKHMTIIGAGYIGIEAAEASRKAGKEVTLLDVIDRPLGTYLDGELTDILAKKLTAEGINVQMNAKITAYTGDQAVKAVKTTDAEYPSDVVIQAAGVQPNTDWLKGTVDLDDRGWIKVDNYLRTNLPDVYAIGDATLAYSIPAQTKVPIALATVARREARYVVKHLFEANPAEPFKGLVGSSALSVFDEHFAQSGLNSFTANRAGVTVAKDFYHTTLRPKYVPSDKGNPDVYVQLFFNPTTHVLLGGAVLSTYDVTAQGNVLALAIQHGLRLEDLAEADFFFQPGFDRQWSLLNLAAQHALGEEPFTY
>NZ_LT854705.1|WP_087741348.1|186401_187325_-|ribokinase
MQDSDVLVIGSNMIDLITYVDRMPVEGETIEAPDFAMGFGGKGANQAVAAARLGSRVSFISMVGHDNFGQQQLANFKANHIDVTGVGVGQKNSGAAPIFVDPSSDNRILIIKGANSELTPAVLDQHVDLLQHTKLIVLQQEIPLATNYHAIDLANQYHVPVLLNPAPANRDLDLTHVSRVDFFSPNETELATLTGMPTTTLTEIKAAAHHLIDLGVKNLLVTLGAKGVLWVCANDCQLIDAIKVQAVDTTGAGDSFIGSFAHYFTQGEDVPTALHHANAYAALTVTRRGTQKSYPTAEEVAQAYQPS
>NZ_LT854705.1|WP_157667835.1|187439_187799_-|helix-turn-helix-transcriptional-regulator
MTATIIQPQPAELRPLNTALSLLDSPWKPLILHRLADHDYRLAELQRTLTACPPATLTTQLAQLVRDQLVVATNGPADTTSYSLSRAGRSLVPLLLTLNRWGRTYLNEIQPVTPAHHDA
>NZ_LT854705.1|WP_087741350.1|187907_188885_-|LacI-family-DNA-binding-transcriptional-regulator
MSRKITIKDVAAEAGVSEATISRALNDSPQVKPATRQRIQKIAQNLGYHPNGLARSIRVQKTNTLGVIIPDILNNFFTHIIRAIEDAAAQAGYDVLIVNTDEQDDREVSALNLMLEKQAAGVIITSAGGPTDYAAQLGNTPAVFVDRMPPAGIATQYDRVLVDNVRGTQDLVTQLIDRGAKRVGIINSAVSMTATERLQGYHQALDAAGQERDPAIEAAARTDNSNVAQMTRQLLVNQRCDGLLAADNTIMDAVLHKLPDLDLPPFQLGSFDDQDWFDFLPQPIVTAKQPIAQIGKTAVDRMIARINQPDLPAEEFRLSAKIITH
>NZ_LT854705.1|WP_157667836.1|189023_189857_-|IS982-family-transposase
MKIIEPVYLTLDKQFRFRCNYQEEKVSDVVILASMLLRIDLRDASEAHFHQMMLASGIQLPERSRYNRRCRKLIPVERYIRFRLLMKYKRPALYEIIDSAPITLVSARRSQEAKVLRPIANKGFNATKQLYFYGFKLHVVLNDQGFPLNWEISTASTDDRKVAEELLLTAPNNQVLADGGYLSQPLKERLFKLYHINLWTPLRKNMAHHKRVNSSLLKNLRRHIETFFNNLNIVGHFEHPGIRTLSGLNARLESMFLWMTINTHRHLLDGKSGLSIT
>NZ_LT854705.1|WP_087741352.1|190120_191284_+|transposase
MLKGIKLRLYPTRAQEGQLWQLFGNNRFVWNQMLAMVKARYKNNPSSRFINEYGMNNLLKALKTEYPFLKLSDSTSLQVVNHHLAQAFSMLFKHRGGQPRFKSRRSAKQAYTGRFPGTQLVVAKRRVKLPKLGSIKTSKTGQLINGLVKRYTVSHDATGRYYLSLQVEFSEPRSLPKKGVQVGIDLGVTNLAITSDGQKYPKFQALWEEKQGTTWQRKFDRRKHQAKVNVIQWNHNKAHLIKLELNDYKNWQRARQIKARYQRKLANRRKDYLNKLTTQLVKTYDVIVIEDLKVKNLMHNHHLAKSIANASWYQFRTMLAYKCRWYGRQLIVVSPNYTSQQCASCGFQSGQKPLEIREWTCPHCGTHHDRDINAAVNILHRGLKTVQ
>NZ_LT854705.1|WP_087741353.1|191616_192045_+|MarR-family-transcriptional-regulator
MQYHHFSQYVAGIYRRSKNDFNRQIEDLDVRATQSDLLMFIYEHPGRQQVQIAQEMSVDPSLLARDLTVLTQKGWITRTPSSTDRRAKEITLTAAGVTLAQRLTATMATWWRQLFAESGLDADQLDQQLAAVYQALLKRERP
>NZ_LT854705.1|WP_087742764.1|192098_192686_+|hypothetical-protein
MAASVALAKIATLGTSPISSIPNVGSLLTPLTIGQVTIIFMVVIIGLEWVVLRRDFGWTNLVQLIPSVFFGTLIDAFVTAFHAIQPTAYWQQLGLTLISIGLLAFGVLLEVNSRTLVMAGEGIAAALAFRYHRPFGAMKVRCDLAMVIGAVLLALVFAHGLIGVREGTVISALLTGRVVSWLETHLSRFTAWVQA
>NZ_LT854705.1|WP_087741354.1|192993_193314_+|hypothetical-protein
MQKWQIGLEWGVNALAVSLPLALLGSGFKGVIDQSPLHPDAVIVLGSIGLVAVSLGGLAVYQRHRTQRYQRWFGWGYGGLLGVGVVLGGLALNPPDWLLRLLIPGY
>NZ_LT854705.1|WP_087741355.1|193414_194131_+|class-I-SAM-dependent-methyltransferase
MKTIRENGLDGVSGLIILYGLGLLCLPVWVLTGFHLAWLIAAGIYLILGSIFLHTTLVGKAHIWDRLLRGVPLDKHTRALDIGCGHGLVMFKIAQRLPLGGHITGIDIWRQLDQTNNSQSAVERRLAVSELTQEATVQTADMRQLPFADQTFNLVVSSLAIHNVKPKAGRLQSLQEIGRVLQPGGRVVLVDLGFSCQEYKEALQRLGFTDIHVSGNGPNGWWGGPWMPTLTLRATKLN
>NZ_LT854705.1|WP_087741356.1|194212_195145_+|pyrimidine-specific-ribonucleoside-hydrolase-RihA
MSTKIILDCDPGHDDALAMMLALANPEIDLLAVTTSAGNQTPEKTLHNAMRLLTLMHHQEIPVAGGNRTPLLKPLETAGNVHGKSGLDGAELPEPDFDVQPLTAIELIAQTLRASADPVTLVVTGPMTNIALFLRVYPELKSHIAQIVFMGGAMGLGNWTPSVEFNIYVDPEAAKIVLNAGIPLVMAPLNVTHKAQIMKPEIEAIGHIDNPVAHAFTGLLNFFEIYHENPKWGFQGAPLHDPCTIAWLLHPEWFQTEKMAVDVETAGELTRGETVCDYYELTGQPKNTEVLLNLNREAFIQLIADSLKTF

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Crispr_ID: NZ_LT854705_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT854705_2

378131-378524

Orphan

I-E,II-B

Consensus_repeat	Method
GTATTCCCCACATGTGTGGGGGTGATTC	PILER-CR
GTATTCCCCACATGTGTGGGGGTGATTC	CRISPRCasFinder
GTATTCCCCACATGTGTGGGGGTGATTC	CRT

6 spacers

The CRISPR arrays of NZ_LT854705_2

>merge|NZ_LT854705|2|378131-378524|PILER-CR,CRISPRCasFinder,CRT
GTATTCCCCACATGTGTGGGGGTGATTCTACCCCCGTCGACTTCGTCAAACGCCTTATCTGGTATTCCCCACATGTGTGGGGGTGATTCCAACTTTTTTGCCAGAAGCTACAGCAGATTTAAGTATTCCCCACATGTGTGGGGGTGATTCTTGGTGACGCTATCGGTTATGCGGTTGCGGTTTGTATTCCCCACATGTGTGGGGGTGATTCCGATGCGCAGACCGGCCCCCGTCAGGAACTTGTGTATTCCCCACATGTGTGGGGGTGATTCCTCCTCGAAGGGTAAGGCCAGTGTGAAGGCTAAGTATTCCCCACATGTGTGGGGGTGATTCTACTGTGATTTATTCGAGTAATCATATTATCAAGTATTCCCCACACGTGTGGGGGTCTTAA

>NZ_LT854705|2|2|378131-378463|PILER-CR
GTATTCCCCACATGTGTGGGGGTGATTC	TACCCCCGTCGACTTCGTCAAACGCCTTATCTG
GTATTCCCCACATGTGTGGGGGTGATTC	CAACTTTTTTGCCAGAAGCTACAGCAGATTTAA
GTATTCCCCACATGTGTGGGGGTGATTC	TTGGTGACGCTATCGGTTATGCGGTTGCGGTTT
GTATTCCCCACATGTGTGGGGGTGATTC	CGATGCGCAGACCGGCCCCCGTCAGGAACTTGT
GTATTCCCCACATGTGTGGGGGTGATTC	CTCCTCGAAGGGTAAGGCCAGTGTGAAGGCTAA
GTATTCCCCACATGTGTGGGGGTGATTC

>NZ_LT854705|2|2|378131-378524|CRISPRCasFinder
GTATTCCCCACATGTGTGGGGGTGATTC	TACCCCCGTCGACTTCGTCAAACGCCTTATCTG
GTATTCCCCACATGTGTGGGGGTGATTC	CAACTTTTTTGCCAGAAGCTACAGCAGATTTAA
GTATTCCCCACATGTGTGGGGGTGATTC	TTGGTGACGCTATCGGTTATGCGGTTGCGGTTT
GTATTCCCCACATGTGTGGGGGTGATTC	CGATGCGCAGACCGGCCCCCGTCAGGAACTTGT
GTATTCCCCACATGTGTGGGGGTGATTC	CTCCTCGAAGGGTAAGGCCAGTGTGAAGGCTAA
GTATTCCCCACATGTGTGGGGGTGATTC	TACTGTGATTTATTCGAGTAATCATATTATCAA
GTATTCCCCACACGTGTGGGGGTCTTAA

>NZ_LT854705|2|2|378131-378524|CRT
GTATTCCCCACATGTGTGGGGGTGATTC	TACCCCCGTCGACTTCGTCAAACGCCTTATCTG
GTATTCCCCACATGTGTGGGGGTGATTC	CAACTTTTTTGCCAGAAGCTACAGCAGATTTAA
GTATTCCCCACATGTGTGGGGGTGATTC	TTGGTGACGCTATCGGTTATGCGGTTGCGGTTT
GTATTCCCCACATGTGTGGGGGTGATTC	CGATGCGCAGACCGGCCCCCGTCAGGAACTTGT
GTATTCCCCACATGTGTGGGGGTGATTC	CTCCTCGAAGGGTAAGGCCAGTGTGAAGGCTAA
GTATTCCCCACATGTGTGGGGGTGATTC	TACTGTGATTTATTCGAGTAATCATATTATCAA
GTATTCCCCACACGTGTGGGGGTCTTAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT854705.1\|WP_087742768.1\|383267_384284_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_LT854705.1\|WP_087741460.1\|373528_374344_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|283645
NZ_LT854705.1\|WP_057733759.1\|375453_375837_+\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NZ_LT854705.1\|WP_087741461.1\|374380_375199_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|369792
NZ_LT854705.1\|WP_087741457.1\|368733_371007_+\|glycoside-hydrolase-family-65-protein	unknown	unknown	gnl\|CDD\|237517
NZ_LT854705.1\|WP_087741467.1\|387686_388733_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_LT854705.1\|WP_087741468.1\|388967_389966_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_LT854705.1\|WP_057733768.1\|371807_372077_-\|30S-ribosomal-protein-S14	unknown	unknown	gnl\|CDD\|181574
NZ_LT854705.1\|WP_057733746.1\|390108_391038_+\|L(+)-tartrate-dehydratase-subunit-alpha	unknown	unknown	gnl\|CDD\|181309
NZ_LT854705.1\|WP_087741455.1\|365722_366688_+\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380517
NZ_LT854705.1\|WP_087741459.1\|372205_373237_-\|galactose-mutarotase	unknown	unknown	gnl\|CDD\|185696
NZ_LT854705.1\|WP_087741469.1\|391037_391649_+\|L(+)-tartrate-dehydratase-subunit-beta	unknown	unknown	gnl\|CDD\|236192
NZ_LT854705.1\|WP_015473476.1\|384470_385400_+\|IS30-like-element-ISLpl1-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_LT854705.1\|WP_087741462.1\|375986_377834_+\|SH3-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|227721
NZ_LT854705.1\|WP_087741466.1\|385492_387556_+\|KxYKxGKxW-signal-peptide-domain-containing-protein	unknown	unknown	gnl\|CDD\|236768
NZ_LT854705.1\|WP_057733755.1\|379027_379456_+\|Spx/MgsR-family-RNA-polymerase-binding-regulatory-protein	unknown	unknown	gnl\|CDD\|239330
NZ_LT854705.1\|WP_087741458.1\|371066_371579_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_087741464.1\|380772_383058_+\|MucBP-domain-containing-protein	unknown	unknown	gnl\|CDD\|380191
NZ_LT854705.1\|WP_087741463.1\|379511_380288_-\|C40-family-peptidase	unknown	unknown	gnl\|CDD\|366353
NZ_LT854705.1\|WP_087741456.1\|367235_368606_+\|SLC45-family-MFS-transporter	unknown	unknown	gnl\|CDD\|340871

Protein	Function_ID	Function_description	E-value
NZ_LT854705.1\|WP_087742768.1\|383267_384284_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	3.88419e-65
NZ_LT854705.1\|WP_087741460.1\|373528_374344_+\|alpha/beta-hydrolase	gnl\|CDD\|283645	pfam06028, DUF915, Alpha/beta hydrolase of unknown function (DUF915). This family consists of several bacterial proteins of unknown function. Members of this family have an alpha/beta hydrolase fold.	4.55331e-38
NZ_LT854705.1\|WP_087741461.1\|374380_375199_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|369792	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase. This family contains haloacid dehalogenase-like hydrolase enzymes.	1.06502e-61
NZ_LT854705.1\|WP_087741457.1\|368733_371007_+\|glycoside-hydrolase-family-65-protein	gnl\|CDD\|237517	PRK13807, PRK13807, maltose phosphorylase; Provisional.	0
NZ_LT854705.1\|WP_087741467.1\|387686_388733_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	9.70688e-25
NZ_LT854705.1\|WP_087741468.1\|388967_389966_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	1.20502e-93
NZ_LT854705.1\|WP_057733768.1\|371807_372077_-\|30S-ribosomal-protein-S14	gnl\|CDD\|181574	PRK08881, rpsN, 30S ribosomal protein S14; Reviewed.	7.09899e-45
NZ_LT854705.1\|WP_057733746.1\|390108_391038_+\|L(+)-tartrate-dehydratase-subunit-alpha	gnl\|CDD\|181309	PRK08230, PRK08230, tartrate dehydratase subunit alpha; Validated.	0
NZ_LT854705.1\|WP_087741455.1\|365722_366688_+\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|380517	cd06294, PBP1_MalR-like, ligand-binding domain of maltose transcription regulator MalR which is a member of the LacI-GalR family repressors. This group includes the ligand-binding domain of maltose transcription regulator MalR which is a member of the LacI-GalR family repressors that are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	9.52422e-65
NZ_LT854705.1\|WP_087741459.1\|372205_373237_-\|galactose-mutarotase	gnl\|CDD\|185696	cd09019, galactose_mutarotase_like, galactose mutarotase_like. Galactose mutarotase catalyzes the conversion of beta-D-galactose to alpha-D-galactose. Beta-D-galactose is produced by the degradation of lactose, a disaccharide composed of beta-D-glucose and beta-D-galactose. This epimerization reaction is the first step in the four-step Leloir pathway, which converts galactose into metabolically important glucose. This epimerization step is followed by the phosophorylation of alpha-D-galactose by galactokinase, an enzyme which can only act on the alpha anomer. A glutamate and a histidine residue of the galactose mutarotase have been shown to be critical for catalysis, the glutamate serves as the active site base to initiate the reaction by removing the proton from the C-1 hydroxyl group of the sugar substrate, and the histidine as the active site acid to protonate the C-5 ring oxygen. Galactose mutarotase is a member of the aldose-1-epimerase superfamily.	4.65547e-111
NZ_LT854705.1\|WP_087741469.1\|391037_391649_+\|L(+)-tartrate-dehydratase-subunit-beta	gnl\|CDD\|236192	PRK08228, PRK08228, L(+)-tartrate dehydratase subunit beta; Validated.	3.05725e-131
NZ_LT854705.1\|WP_015473476.1\|384470_385400_+\|IS30-like-element-ISLpl1-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	3.5414e-69
NZ_LT854705.1\|WP_087741462.1\|375986_377834_+\|SH3-like-domain-containing-protein	gnl\|CDD\|227721	COG5434, PGU1, Endopygalactorunase [Cell envelope biogenesis, outer membrane].	6.22436e-05
NZ_LT854705.1\|WP_087741466.1\|385492_387556_+\|KxYKxGKxW-signal-peptide-domain-containing-protein	gnl\|CDD\|236768	PRK10819, PRK10819, transport protein TonB; Provisional.	8.65873e-16
NZ_LT854705.1\|WP_057733755.1\|379027_379456_+\|Spx/MgsR-family-RNA-polymerase-binding-regulatory-protein	gnl\|CDD\|239330	cd03032, ArsC_Spx, Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex formation between RNAP and certain transcriptional activator proteins like ResD and ComA. In response to oxidative stress, Spx can also activate transcription, making it a general regulator that exerts both positive and negative control over transcription initiation. Spx has been shown to exert redox-sensitive transcriptional control over genes like trxA (TRX) and trxB (TRX reductase), genes that function in thiol homeostasis. This redox-sensitive activity is dependent on the presence of a CXXC motif, present in some members of the Spx subfamily, that acts as a thiol/disulfide switch. Spx has also been shown to repress genes in a sulfate-dependent manner independent of the presence of the CXXC motif.	2.84856e-39
NZ_LT854705.1\|WP_057733759.1\|375453_375837_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	2.15836e-10
NZ_LT854705.1\|WP_087741464.1\|380772_383058_+\|MucBP-domain-containing-protein	gnl\|CDD\|380191	NF033187, internalin_J, class 1 internalin InlJ. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface-anchored proteins with an N-terminal signal peptide, leucine-rich repeats, and a C-terminal LPXTG processing and cell surface anchoring site. See PMID:17764999 for a general discussion of internalins. Members of this family are internalin J (InlJ).	3.90685e-33
NZ_LT854705.1\|WP_087741463.1\|379511_380288_-\|C40-family-peptidase	gnl\|CDD\|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	3.55013e-30
NZ_LT854705.1\|WP_087741456.1\|367235_368606_+\|SLC45-family-MFS-transporter	gnl\|CDD\|340871	cd17313, MFS_SLC45_SUC, Solute carrier family 45 and similar sugar transporters of the Major Facilitator Superfamily of transporters. This group includes the solute carrier 45 (SLC45) family as well as plant sucrose transporters (SUCs or SUTs) and similar proteins such as Schizosaccharomyces pombe general alpha-glucoside permease. the SLC45 family is composed of four (A1-A4) vertebrate proteins as well as related insect proteins such as Drosophila sucrose transporter SCRT or Slc45-1. Members of this group transport sucrose and other sugars like maltose into the cell, with the concomitant uptake of protons (symport system). Plant sucrose transporters are crucial to carbon partitioning, playing a key role in phloem loading/unloading. They play a key role in loading and unloading of sucrose into the phloem and as a result, they control sucrose distribution throughout the whole plant and drive the osmotic flow system in the phloem. They also play a role in the exchange of sucrose between beneficial symbionts (mycorrhiza and Rhizobium) as well as pathogens such as nematodes and parasitic fungi. There are nine sucrose transporter genes in Arabidopsis and five in rice. Vertebrate SLC45 family proteins have been implicated in the regulation of glucose homoeostasis in the brain (SLC45A1), with skin and hair pigmentation (SLC45A2), and with prostate cancer and myelination (SLC45A3). Mutations in SLC45A2, also called MATP (membrane-associated transporter protein) or melanoma antigen AIM1, cause oculocutaneous albinism type 4 (OCA4), an autosomal recessive disorder of melanin biosynthesis that results in congenital hypopigmentation of ocular and cutaneous tissues. The SLC45 family and related sugar transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.17808e-111

>NZ_LT854705.1|WP_087741462.1|375986_377834_+|SH3-like-domain-containing-protein
MNGGAFLKLRGKQYLLAAVTLGVTLLEFTAGGADLTPSTTVVAHAATTINAVHQGMTGDAKTVNNDAFQAMIDKFNNSDGVTVHVPKGTYVFNAGHVVLHSNITFNFDKGAVFRITNGQRLNIAYPSPQAGYDGGISNVTWNGATFQGDNTAAGQSVFVQSIHHAQDVTFNNCVFDNAESPTGHYIDIDGSHDVTVKNSVFTGFNGSMDYKEAIQVDYSNKKAMSYKLAGDQYDNLPSYNVTVDHNQFLPVSRKSGQVQSYAPNPIGEHAVYNKGQAGIIHNVYFTNNTVVDPKPLLDDGVATIHFKCVSDLYITGNKFINQHVLGSGNYIYLYNSQPNYQMSNLNITNNTFTNVNPTKQYVYLDSGTTDNPMTDVTIKNNNVTTQKKGVPFVQSNFPLTGSGNGIQISNNKIKVAKPVATTVATPTITQTTVKPNKKGQKLKKRPQTNKKETYVSGLSTQHAQLKSNYKTYSLYNHIRGHKNWNIMKYDWKKLKNKRVYLDMRATADSGQWYRIRLSKNATTKYWIRKGALQFDKITTSEYSRELTLMKIYPVYNNVFNDSALAKQKGTTADISNRRVTITHRAYRIDSNGHQTVYYQMENGLWTRASAFDLNS
>NZ_LT854705.1|WP_057733759.1|375453_375837_+|winged-helix-turn-helix-transcriptional-regulator
MTQTNELSQSLEWFSQLQKIMRPVTTIKTDEITISLEQFNLLHAITDQRDDFTPTKFANQIGVSKSMISGQISRLLRAGLIESIASKVDRRQHNLKLTPEGVKVYTQVRGQVVDRLNQLHDDISKMM
>NZ_LT854705.1|WP_087741461.1|374380_375199_-|Cof-type-HAD-IIB-family-hydrolase
MTKIKMIATDVDGTFLNQQRQYDHDRFAQQLQRLQAADIRFVVASGNHLGHLHQVFAPTPAVQTFVAENGSLIVDHGQTLFQTTIPLPVVREVVAAILADDTIRPQVLRLSGQHGTYINRADHSNDPASQAYYFNNVVLVDDLTAVDDTIYKINGEWPNQTIQSLAAKLNAKFPHQIHAAASGFGSIDIIAPHMNKAIGVTQLAQAWNIAPSEIAAFGDNDNDLEMLRHVGFGVAMRNGTDTVKQVANLITPTDNDHDGVLNVIDAILDQKV
>NZ_LT854705.1|WP_087741460.1|373528_374344_+|alpha/beta-hydrolase
MENKWRWLPVVLGGGWLGYHWLSRRTGRPLPKAARPDSQATPTPTVFIPGWGGNAWTYNGMLRWFARQGYAAKVLTVRVDYRNHLHFRGTWTGQADNPTIQVLFDRNLTLDYRQQTRWVTQILRALHRRYGVTSYNAVAHSWGGSAMVQSLVQDGADPSLPRLRRLILLGTPVDESQTDQPDPAYQRLLTLRQNLWANAGAEIHNVYGRLAGHATDGQVPVWQATAFREVVAQSPIHYTEHPIPGLGHGRLHSALKMWQLIAQLLWVKKDD
>NZ_LT854705.1|WP_087741459.1|372205_373237_-|galactose-mutarotase
MQTTATKWDTYQNQPVTQYEIENDNGVKLGVLSWGATLHKLMVPGNHGEHNMVLSYHKMTNYLDNPFYVCMGIGRTGGRITRGTVTVDGQTYHLDTNEGKNTLHGGPNGFNTVNWDGTIDDSNPDIAKIILTHTFKSTDDSYPGDLTAKIIWTLDNHDQVTLTFEGTATATTLFNPTSHLYFNLSDDPLIVGETLQVNSHEHLDLNDEKLPTGKMIPVADTPYDFSKGQNLGEAIDALQGIPEKGFDDVFHLDPAADGTIAKLSDPKSKRSVTMKSDRNALVVFTANSFDKSLKLTTGDGQPYMGVALEPQNLPDSMNHDGFGDITLPAGKTQTYHVSYDLTY
>NZ_LT854705.1|WP_057733768.1|371807_372077_-|30S-ribosomal-protein-S14
MAKKSKIAKEKKIEATVAKYATKRAELKAAGDYAGLALLPRDASPVRMHHRDHLDGRPHAYMRKFGLSRLNFRDLAHKGQIPGVKKASW
>NZ_LT854705.1|WP_087741458.1|371066_371579_-|hypothetical-protein
MPVESIGWEFDVLQANSFDDNYPRLEAVFVGIAPAVAYDAQNQPKFKRNIERRLRDLEKQLRRDHQADLSALGSADLAHNATIIQNLVADYHTQITQQILITGQLELESLTLAGEWPLFWNQTSTLVQQKDHEREPMPFSEPTPAPDAGPTTDHADDTDDPGTDNPYTPV
>NZ_LT854705.1|WP_087741457.1|368733_371007_+|glycoside-hydrolase-family-65-protein
MKRIFDVQPWNVVTHTFDPKDKRLQESMTSLGNGYMGMRGDFEEGYSGDSLQGIYLGGVWYPDKTRVGWWKNGYPKYFGKVVNAVNFIKLPIEINGQRVDLAKDQISDFTLDLDLHTAVLTRSFTLKRGDVKVALTFERFLSVAQKELSVQKVTVKNLSATNVDVKLLPAIDADVMNEEANYDERFWDVLATDQQADRGSVIAKTTPNPFGTPQFTSGMEMRMVSDLDNVAIDQPNDKEVATAYQGTLAPQTATTLEKRVIVVTSRDYKTQADLTTAMHQLSDQVAKESYADLLTAHTQVWAQRWEKSDVEITGDDESQQGIRFNLFQLFSTYYGEDSRLNIGPKGFTGEKYGGATYWDTEAFAFPVYLGITDPKVTRNLLMYRYNQLPGAYINAKEQGLKGALFPMVTFDGIECHNEWEITFEEIHRNGDIAFAIYNYTRYTGDDSYVLHQGAKVLTEISRFWADRVHFSKRNNQYMIHGVTGADEYENNVDNNWDTNMLAQWTLKYTLEILGKVDADVAKRLDVSDDEKAHWQDIVDRMYLPYDKDLNIFVQHDGFLDKDIEPVSAIPADQRPINQHWSWDKILRSPYIKQGDVLQGIWDFIDDYTPEQKKANFDFYEPLTVHESSLSPAIHSVLAADLHYEDKAVELYERTARLDLDNYNNDTTDGLHITAMTGGWIAVVQGFAGMRVRNGQLHYAPFLPKKWNSFSFRQVFRGRLIEVIVDQAGAHFKLLSGDPLDIDVAGKTVSLQPDTVVE
>NZ_LT854705.1|WP_087741456.1|367235_368606_+|SLC45-family-MFS-transporter
MADVVSKDTTTVDNPKTGLPNLSASTIWMINFGFLGVQTAFTLQSSQMSRIFQTIGADPNSLGWFFILPPLAGLIVQPIVGYYSDRTWAPRLGGRRLPYLALGTIVAVIVMCLLPNSGSMGFGYASLAALLFGAITVAFLDLSSNIAMQPFKMMVGDMVNDDQKSYAYGIQSFLSNTGAVLAAILPFLFAYFGLKNVAVKGVVPDTVKVAFYVGAILLVITSLFTIFRVHEYDPETYAKYHGISKEDNTTGGNWWTLLKSAPKAFWTVTLVQFFCWVAFQYLWTYSAGAIASNVWNTTNAASAGYQAAGNWYGVLAAVQSIAAVVWSYVLAKLPNSVHKLGYAGSLGLGAVGFISVFFIHNQYALIVSFILVGIAWAAMNTYPLTMVTNALSGAHIGTYLGLFNGSICLPQIVASLASFALFPLLGGAQANMFLLAGIIMAIGALSVFTIKETYKA
>NZ_LT854705.1|WP_087741455.1|365722_366688_+|LacI-family-DNA-binding-transcriptional-regulator
MLTIRDIAAKAGVSVSTASRALNNNPRISQATRDRIQKLAAAEGYLPNYNAKNLTAGEANAVGVVFPNTERVLSENPFYIDLLRGINAQLVQRHYVLSVAISSTAEELLANVKSMVAQGKIKRFILFYAHQDDPIADYLRQQHLRFVTIGQPDQHHNDFFVDNDNLQAGIGGATFLFDQLHVKHPVFVESGHHWAYEQQRREGYDRVAARFNVEPLVCKLGDATRVRAFIDQHPEIDGIMATDDFNGIEFYRLFREKYGVSKFPVVSFNHSLPEGLTDADLHSVDLFPEKMGSAAAKLLFSDREPIDTPTPGQIRIPYAIN
>NZ_LT854705.1|WP_057733755.1|379027_379456_+|Spx/MgsR-family-RNA-polymerase-binding-regulatory-protein
MIKMYFHAKTTAVTKAMKWLANHDAIFTARDIKKQPLTRDEILYMLSLTEDGTDDLISTRSKAYKALPNSVQDMGMNELVELLQTNPGILKNPIVVDRNKLATGFDLETIREFVPASYRKKELANFFKILNGTKKSLNVSPA
>NZ_LT854705.1|WP_087741463.1|379511_380288_-|C40-family-peptidase
MLKIKQLSLTVATAAAFLPVWGLTTTASANTTNTINSTSSMPDTQYVRKSATGWTYNLGGTASNMTFGKKTHYLKNYPNTTWHATQKRYITKKNGVKYLYYYVTNGKKTASGWIWHGYLQKKSYSHTTSTTSTKGTGTYASVLKAAQAQLGKPYVYGGNGPSSFDCSGFTKYVFKQAIGQTLPRTAQAQYNAYDHVSASNAKPGDLIFFGTSTSNITHCGIYLGNHKMIDAQLRGVVTEATNVSWWHTVGYARPATLS
>NZ_LT854705.1|WP_087741464.1|380772_383058_+|MucBP-domain-containing-protein
MTHVTKRSTTRWWSQSLTVVSLTAVCLTGGPLTAVAGTTTTADRATTTATKSKPKADESIDSWMPNKRLQETVLKDLKDDNPNKEWQSVSEITKDDMQLLKSLHDTQHVYIDGKTEYSLEGLQYATNLERLTLGGDLNYHPVRLNADIVDVTPLKDLQSLKVLNLQYNRLKDVSPLAGLKNVTQMSLGWNYIEDFSMLPISQYEQFTYINQFIERPTVNISAKSRSAHLKVALKFKSSTPVELEAPSGYARLSDWTPDDKIFRSYYFNGGTGTPDGQGGLKFTDIVDQEPGPTELPGQNVTPLPDKFYLLGKDKDGIFKVAQPYKLAAEAKPVTVKYQDQDGKSLHDDIVLEGVVGDHYITEQLELPGHAFKEVKGAAQGEFSDQAQTVTYVYTKDPVKAQAVTVKYQDENGKSLRDDIVLNGNVGDDYTTERLTLPGYTFKEIKGEPQGKLGDQAQTVTYVYTKDPVAGKPITVKYVSTTGEEIAPDVTLNGDTGAPYEAERLDIPGYEWTKAEGNEKGTFGDQAHTITMIYTPIEGDGGSGDGSDGGDTGGNSSSSSSSSTDSSSDSSSDSSSDSSSDSNSNSNSNSSSDSSSSTDSSSSTDSNSSSDSNSNSSSNSSSSSNSSSNPDSSSSSSSNSSSSSSSSTGSGSSSHTDSGSDQPTAPVTDEQDDDVTGGPGTIGPAGPFEGGLDSDQPGGSTGGTSPFENDLTPTIFPTQGTTTIDGNLPQTNEQRGRLGAWLGAALLATVGLTWFSRRSRQK
>NZ_LT854705.1|WP_087742768.1|383267_384284_+|IS30-family-transposase
MTHSQINTHKHYQQLSLSDRATIQALRATGDTATVIAQKLHRSKATISREITRGSVTQLDSKRPSHQVYLAETAQAIHDRKRDSTGHHAFLKTGRAFFKALPKELTRKPRVHSVDSFVHFYRDQGKSCPSTTTVYRYIDAGLLELDNMTLPKKLRRRVKGYKNAHKRKSKKIYGDSIELRPAAVNDRTGVGHWEGELVKGIRSADEPALMTLTERYSRTEIIVKIPDYHADTCLKALQDTINDYGAKEVESITFDNGSEFAKLSEIVGTQIYFAHPYSPWERGTNENTNGLLREYFPKGKSLRDVTLVEVQAVQSALNHRPRRILNYLRPCDYYRRMA
>NZ_LT854705.1|WP_015473476.1|384470_385400_+|IS30-like-element-ISLpl1-family-transposase
MSSITYSERIKIETFCELGLSNIQMGVRLNRSPSTISYELSRCQPYQAELAQTDAEYKRSRCGRKTKLSDELKQKILNHLRLSWSPGMIAHEFKLATKSIYNWLNQGRIDFSLNDLPEHGVRQRRNVDQRSKYNQSLGRSIEQRPMMINQRNRIGDFELDTVVGPRGHSKAVLLTLIDRKSRFLWAYRLKDRTTATVNEALTKFLTTFNGPVHSFTVDRGTEFSGLVSLESQYGIKTYYCHAYTPAERGSNERFNRNLRYFYPKGTRFEHISAQDLTTTLLQINQRPLKILDWQTPYQVMLTNLSKNSD
>NZ_LT854705.1|WP_087741466.1|385492_387556_+|KxYKxGKxW-signal-peptide-domain-containing-protein
METKRTHFKMYKDGRKWVFACALVLALGGGTTVAHADSNSSSDQSATSQVATGSDSSTSSQNTSTSSTANSTAKPDTTEGTTTQTSGATKVTTSGDDENGKNNANTNAVVESTKLADSSAVTDSSQSQQNQASQPDQKTDANADSTQPNQSSQQAKQFAQTAQNVSRTAKSTVPSGGSVYDDYPTLEDDNLLGVSSAFHIFARDAELNAHTNGNLAVQNLAGNVNFGTNIIEELLDKDISYIQNFTNLASSSFVSAGDTRENKVIFGEGITVDVSNPNRPKVNGIDIDHLVASEVYQDQNGQTYIDFDKEFEKLRNKNANFAAANSVRDYTAADFDDQNNRVIDVTDMTPDENGRIVLNLSPEVLQTSTPLTIKGLSPDADGNTVIINVDTGSDPDYSIKSQIKIIYSDGTDRNNQETEDFGDNHLLWNFIDRSATDQQYTGTIHVDATLQGSVLAPSATVEANQNLDGNIIADKVIVNSETHRWDLQDNKNPKPEPEPEPEPETPEPEPEPEPEAPEPETPEPEPEPEPEPENPEPETPEPEPETPEPETPGTESPEPESPEPETPVTEEPDVEEENSYAHHHQDDEIVEEFEEEIAADTTEAQREVTLEKLETAIAEAKAAHDTTLVAQLEAIEQQLLVAMGRSTSVGTGLPQTGEAHSSWAQLLGLSLAGSLLGGWLVRRKRQN
>NZ_LT854705.1|WP_087741467.1|387686_388733_+|helix-turn-helix-transcriptional-regulator
MENLAPAPLAPHEQYLDHVQVDYDLLVYTVGSYHYNWHHQIELFWLLAGDVEVNVDGTRHVLHQNDLLAINSNCGHATFALASNCIALRLHLDPAFFTRQGLDLSHGQFELNSAALKLNVNYAPLRQALAQLALAPQQTTSAFERNALIYQVTALLWRGFFNAAAPTRHLPQRRQGSIENVMTYLNNAYAQDVTLETAAQIGNYSPSYLSRIFKEELGINFYEYLVRCRLQHAVLDLSETTDKIGDIALANGFKEIKSFNLMFKKHFGQTPSTYRQQLSPTVRGQNDHFKRALTPAQSREVHDRLTQVATAQRGNLVSPCESCVYRLHERDYQDLKAKVDQLKSVLNH
>NZ_LT854705.1|WP_087741468.1|388967_389966_+|IS30-family-transposase
MSPYTHLTLKDRECILLGVTLSYTYQVIANQIGCSKATVSREIKRNGGRDAYSAVKAQQNYHQRRLKSRRPRLLADLKLRDFVLHCILQRQWSPEQIAGRLSFEGSSWHISHNTIYRGIEQDNLGVKRKNHGARGFARKLRHRGKTRKVKGTINERRGRFNDVPSVHERPISCENRTRFGHWEGDTVRGKVGRSALVTLVDRKSRYLLSQRVPKVNAKNVTQAMIDLLHTVTPKRVRTLTPDRGTEFAGYREVGEELDIPVYFPDPHAPQQRGTNENTNGLIREYFPKGTDLDKLTDQDINKFVRDLNNRPRKVLGWKSPSEIFFGKKLHLI
>NZ_LT854705.1|WP_057733746.1|390108_391038_+|L(+)-tartrate-dehydratase-subunit-alpha
MDTMTYDYTEPVLSPKGQKMRDILADYITVVSHRLPDDVTKKLVELSKIEVDPLQRLIYDTMMENQMLAGKLKRPSCQDTGALQFFIKCGAKFPLLSELNAILKDAVYRATKQAPLRHNAVQTFDEFNTGMNIGDGIPSVFMQIVDDSADIEMYVYMAGGGCTLPGEAKVLMPGEGYEGVVRFVMDRMTSYGINACPPLLVGVGVGTSAETAALNSKLALMRRVDSVSPNKNAAKLEHLLEDGINHIGLGPQGFGGKASVMGVNVINTARHPSAIGVGVSTGCWSHRRGKINFDSDLNYDLPLNEGVEL
>NZ_LT854705.1|WP_087741469.1|391037_391649_+|L(+)-tartrate-dehydratase-subunit-beta
MKTWHLTTPIADEDIKDIRIGDIVYLNGSMTTCRDVAHRRLVEEHRPLPIDVSHKAILHAGPIIKANDDGTYEMVAVGPTTSMRMEKFEEDFVKETNVKLIIGKGGMGPGTQAACKKYKALHLVYPAGNAVYAALHVEKIVDAQWKDLGMPETLWSCQVKDFGPLIVSIDTNGDNLFEKNKIEFNKRKEAEIKKIDAQVKFIK

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Crispr_ID: NZ_LT854705_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT854705_3

816550-816760

Orphan

I-E,II-B

Consensus_repeat	Method
GTATTCCCCACACGTGTGGGGGTGATTC	CRISPRCasFinder

3 spacers

DEDDh

The CRISPR arrays of NZ_LT854705_3

>merge|NZ_LT854705|3|816550-816760|CRISPRCasFinder
GTATTCCCCACACGTGTGGGGGTGATTCCAGCTGGTGGGCCAGATGACGGCTCAAATCGTCGTATTCCCTACACGTGTGGGGGTGATTCTGCCCGAGGAAATCTCGAACGCGAGCTTACTGCGTATTCCCCGCATGTGTGGGGGTGATTCCCAGCTCGGCGCCAGATGCTATCTGGCTAACTGGTATTTCCCACACCTGTGGGCATCAAAA

>NZ_LT854705|3|3|816550-816760|CRISPRCasFinder
GTATTCCCCACACGTGTGGGGGTGATTC	CAGCTGGTGGGCCAGATGACGGCTCAAATCGTC
GTATTCCCTACACGTGTGGGGGTGATTC	TGCCCGAGGAAATCTCGAACGCGAGCTTACTGC
GTATTCCCCGCATGTGTGGGGGTGATTC	CCAGCTCGGCGCCAGATGCTATCTGGCTAACTG
GTATTTCCCACACCTGTGGGCATCAAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT854705.1\|WP_087741707.1\|828933_830364_+\|glucosaminidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|224619
NZ_LT854705.1\|WP_087741240.1\|804790_806053_-\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
NZ_LT854705.1\|WP_057731075.1\|812370_813135_-\|exodeoxyribonuclease-III	unknown	unknown	gnl\|CDD\|197321
NZ_LT854705.1\|WP_057731078.1\|809327_809861_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_LT854705.1\|WP_057731071.1\|814340_816473_+\|sodium:proton-antiporter	unknown	unknown	gnl\|CDD\|223104
NZ_LT854705.1\|WP_172825269.1\|828132_828837_+\|6-phosphogluconolactonase	unknown	unknown	gnl\|CDD\|238693
NZ_LT854705.1\|WP_087741699.1\|807688_808666_+\|phosphate-acetyltransferase	unknown	unknown	gnl\|CDD\|236609
NZ_LT854705.1\|WP_057731069.1\|816819_817473_-\|DUF1361-domain-containing-protein	unknown	unknown	gnl\|CDD\|369208
NZ_LT854705.1\|WP_057732069.1\|830567_831653_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224057
NZ_LT854705.1\|WP_057731083.1\|806927_807641_+\|uracil-DNA-glycosylase	unknown	unknown	gnl\|CDD\|235376
NZ_LT854705.1\|WP_087741705.1\|824342_827666_+\|SEC10/PgrA-surface-exclusion-domain-containing-protein	unknown	unknown	gnl\|CDD\|275124
NZ_LT854705.1\|WP_057731076.1\|811812_812349_-\|3'-5'-exonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
NZ_LT854705.1\|WP_087741700.1\|808858_809335_+\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE	unknown	unknown	gnl\|CDD\|376771
NZ_LT854705.1\|WP_057731073.1\|813413_814325_+\|UDP-N-acetylmuramate-dehydrogenase	unknown	unknown	gnl\|CDD\|237553
NZ_LT854705.1\|WP_087741704.1\|821309_823124_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_LT854705.1\|WP_087741233.1\|823342_823798_+\|IS200/IS605-family-transposase	unknown	unknown	gnl\|CDD\|376616
NZ_LT854705.1\|WP_087741702.1\|818608_819571_+\|cell-surface-protein	unknown	unknown	gnl\|CDD\|227193
NZ_LT854705.1\|WP_087741701.1\|809886_811584_-\|IS1182-family-transposase	unknown	unknown	gnl\|CDD\|226192
NZ_LT854705.1\|WP_057731068.1\|817760_818609_+\|TIGR00159-family-protein	unknown	unknown	gnl\|CDD\|224539
NZ_LT854705.1\|WP_087741703.1\|819609_820968_+\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670

Protein	Function_ID	Function_description	E-value
NZ_LT854705.1\|WP_087741707.1\|828933_830364_+\|glucosaminidase-domain-containing-protein	gnl\|CDD\|224619	COG1705, FlgJ, Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion].	1.22636e-47
NZ_LT854705.1\|WP_087741240.1\|804790_806053_-\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.75929e-54
NZ_LT854705.1\|WP_057731075.1\|812370_813135_-\|exodeoxyribonuclease-III	gnl\|CDD\|197321	cd09087, Ape1-like_AP-endo, Human Ape1-like subfamily of the ExoIII family apurinic/apyrimidinic (AP) endonucleases. This subfamily includes human Ape1 (also known as Apex, Hap1, or Ref-1) and related proteins. These are Escherichia coli exonuclease III (ExoIII)-like AP endonucleases and they belong to the large EEP (exonuclease/endonuclease/phosphatase) superfamily that contains functionally diverse enzymes that share a common catalytic mechanism of cleaving phosphodiester bonds. AP endonucleases participate in the DNA base excision repair (BER) pathway. AP sites are one of the most common lesions in cellular DNA. During BER, the damaged DNA is first recognized by DNA glycosylase. AP endonucleases then catalyze the hydrolytic cleavage of the phosphodiester bond 5' to the AP site, and this is followed by the coordinated actions of DNA polymerase, deoxyribose phosphatase, and DNA ligase. If left unrepaired, AP sites block DNA replication, and have both mutagenic and cytotoxic effects. AP endonucleases can carry out a variety of excision and incision reactions on DNA, including 3'-5' exonuclease, 3'-deoxyribose phosphodiesterase, 3'-phosphatase, and occasionally, nonspecific DNase activities. Different AP endonuclease enzymes catalyze the different reactions with different efficiences. Many organisms have two AP endonucleases, usually one is the dominant AP endonuclease, the other has weak AP endonuclease activity; for example, Ape1 and Ape2 in humans. Ape1 is found in this subfamily, it exhibits strong AP-endonuclease activity but shows weak 3'-5' exonuclease and 3'-phosphodiesterase activities. Class II AP endonucleases have been classified into two families, designated ExoIII and EndoIV, based on their homology to the Escherichia coli enzymes exonuclease III (ExoIII) and endonuclease IV (EndoIV). This subfamily belongs to the ExoIII family; the EndoIV family belongs to a different superfamily.	1.73474e-153
NZ_LT854705.1\|WP_057731078.1\|809327_809861_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	6.84457e-17
NZ_LT854705.1\|WP_057731071.1\|814340_816473_+\|sodium:proton-antiporter	gnl\|CDD\|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	1.12254e-74
NZ_LT854705.1\|WP_172825269.1\|828132_828837_+\|6-phosphogluconolactonase	gnl\|CDD\|238693	cd01399, GlcN6P_deaminase, GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or deamination. It is the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate (GlcNAc6P). GlcN6P deaminase is a hexameric enzyme that is allosterically activated by GlcNAc6P.	4.31436e-118
NZ_LT854705.1\|WP_087741699.1\|807688_808666_+\|phosphate-acetyltransferase	gnl\|CDD\|236609	PRK09653, eutD, phosphotransacetylase.	0
NZ_LT854705.1\|WP_057731069.1\|816819_817473_-\|DUF1361-domain-containing-protein	gnl\|CDD\|369208	pfam07099, DUF1361, Protein of unknown function (DUF1361). This family consists of several hypothetical bacterial proteins of around 200 residues in length. The function of this family is unknown although some members are annotated as being putative integral membrane proteins.	1.87883e-37
NZ_LT854705.1\|WP_057732069.1\|830567_831653_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224057	COG1134, TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	1.38594e-103
NZ_LT854705.1\|WP_057731083.1\|806927_807641_+\|uracil-DNA-glycosylase	gnl\|CDD\|235376	PRK05254, PRK05254, uracil-DNA glycosylase; Provisional.	1.40258e-146
NZ_LT854705.1\|WP_087741705.1\|824342_827666_+\|SEC10/PgrA-surface-exclusion-domain-containing-protein	gnl\|CDD\|275124	TIGR04320, hypothetical_protein, SEC10/PgrA surface exclusion domain. This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.	3.09922e-27
NZ_LT854705.1\|WP_057731076.1\|811812_812349_-\|3'-5'-exonuclease	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	1.675e-85
NZ_LT854705.1\|WP_087741700.1\|808858_809335_+\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE	gnl\|CDD\|376771	pfam02367, TsaE, Threonylcarbamoyl adenosine biosynthesis protein TsaE. This family of proteins is involved in the synthesis of threonylcarbamoyl adenosine (t(6)A).	9.98237e-64
NZ_LT854705.1\|WP_057731073.1\|813413_814325_+\|UDP-N-acetylmuramate-dehydrogenase	gnl\|CDD\|237553	PRK13905, murB, UDP-N-acetylmuramate dehydrogenase.	8.52371e-164
NZ_LT854705.1\|WP_087741704.1\|821309_823124_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_LT854705.1\|WP_087741233.1\|823342_823798_+\|IS200/IS605-family-transposase	gnl\|CDD\|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	1.05327e-47
NZ_LT854705.1\|WP_087741702.1\|818608_819571_+\|cell-surface-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	4.26514e-47
NZ_LT854705.1\|WP_087741701.1\|809886_811584_-\|IS1182-family-transposase	gnl\|CDD\|226192	COG3666, COG3666, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	6.21968e-21
NZ_LT854705.1\|WP_057731068.1\|817760_818609_+\|TIGR00159-family-protein	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	4.336e-96
NZ_LT854705.1\|WP_087741703.1\|819609_820968_+\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0

>NZ_LT854705.1|WP_057731071.1|814340_816473_+|sodium:proton-antiporter
MPILEAVILLIVLVLLSNIISHYLTFIPVSLIQIALGLVVALIWKFQIELETDWFLLLFIAPLLYNDGRRFPRRELWRLRGPIFANAIWLVFLTTILGGFLIYWLIPKMPLTVAFALAAILSPTDPVAVQSISKQVKLPENLMHLVSGESLINDASGLIAFKYAIAATVTGAFSLKTATSDFIYISIVGFLAGLIIMTGIQLLMDVLRRQGIDDVVFNTVLQIATPFVVYLVTEEIAHASGVIAVVTAGVLYHARESQIVEDSPELKLVTEKVWDIIIYSLNGIVFVILGIELPVATSQVIKGGQFNTGEAMLFALGTWVIIVVLRTVWTYGYILFQRIRKTTTEHPSFRMAVLSGLSGVRGAVTMAGVLSVPLTVASGAGFPTRALMLFVASGVIIISLVAATIMLPLISTDGQPLKTRASVSDDIDNDLDLDDEEDEYPEEPVRQISEDEARAYIMRLAISKIEEMRRPNNQRAAYDLILDYQFVIRRLEMSYRADDTMQKVLNDELKLREVALAGERAELKELRQGAKITQTSYVGALRRIERLESRVTQASGRSMPSVLHYWLLFFKHLWRNAAYWLHSEDTDRLHAESNLIERQTAKAAIKTLSQYLSRTDVDETQFDNQAIYHLIVHYRNRIERAKAAAAPSHEEEYQHQFNKLRVRALSAERTGIQNLLEAGNISWAMASRLRQYVNYAENVLVMSLSSDEGD
>NZ_LT854705.1|WP_057731073.1|813413_814325_+|UDP-N-acetylmuramate-dehydrogenase
MMEDIATAFPAVEILRHEPLAHYTHTKTGGPADFLAFPTNVQETKSLLAYANQLKLPITVVGNASNLIVRDGGIRGLVMILTKMDQITVDDAAHTVTAAAGAALIKTTQVAQAHSLSGLEFAAGIPGSVGGAIFMNAGAYGGEIAKVATAAEVLTPDGEIRTLTQTELDFGYRHSSIQDYHDIVLTATFTLEPGDGTAIQAQMDDLNAKRAAKQPLDLPSCGSVFKRPEGHYTGQLIQEAGLQGLKWGGAQVSTKHAGFIVNIDHATATDYLELIHHIQTVIWDRDQVHLETEVRIIGEEPHA
>NZ_LT854705.1|WP_057731075.1|812370_813135_-|exodeoxyribonuclease-III
MKFISWNVNGLRAIVKKNFMATFQDLDADFFGIQETKLQAGQIDLDIPGYYQYWNYAERKGYSGTALFTKHKPLAVHYGIDAPDFDHEGRAITLEYPDFYVMTCYVPNSGTKLKRLDFRMGWEDAFLTYINQLNAKKPVIYCGDLNVAHEEIDLKNPKSNHHNAGFSDEERGKFSTLLAAGYLDTFRHFYPDATGRYSWWSYRFHARDNNAGWRIDYFVTSQRLQNQLQDAKILDQVMGSDHCPVELDVADLTV
>NZ_LT854705.1|WP_057731076.1|811812_812349_-|3'-5'-exonuclease
MNFVAMDFETANGKRYSACSLALTIVRNSQVVDEFYSLIKPDTDFFWRNVQIHGIHEADVANAPTFPEVWEHVAPFFQRDRLVIAHNAPFDNGVLRSSLEHYRLPAARYLTLDTVKTSRKFFPEFPNHKLDTVCEQLNIDLHHHHNALDDSLACANILLYEANHFGTQPLKSFIKVNA
>NZ_LT854705.1|WP_087741701.1|809886_811584_-|IS1182-family-transposase
MQMNYTNNQTTLKLELDWEPEEHHIAWAITTLVDSIPTGDLEAESSWTGRPEYPVKMLLKMLLFSYSRSVFSGRKIAEMGDENLVMRWLMGNIVTVPSYRTINRFRVHPRTKTLIKRLYSLFRTQLTSLGLIDDSALYIDGTKLAANANKYTFVWRKSVEKNEPKLDEKSNQLYDQIIQNEVDLAVRQETDGSLDSTELKAVSDKVSNEIDNLNQVIANEKVKPGGSQNKRRRRKLKHYNHLLKTDLIPRKQNYEFANRTFGERNSFAKTDTDATFMRMKEDPMKNGQLKPGYNLQVASQHQYTLYFDLFQRPTDTRTLVPFLSSIFTQAPNASQYVVADAGYGSEMNYQFISDDLEKDFLIPYGMYEKEQTRAYHKDKRKVANWDYDEYNDCYTDLDGIEFRFHNYSIRHDRYGTERKFKVYWAVDYFEDPQRQELATTQSGRPRQISINANWEYFKNKAKEQLSSEIGRQLYGQRKIDVEPIFANLKAHLAFKRFSVRGLSATWNEVGIALMANNLVKLAKVAANLKEHGQKQEGNSHKSRISFLFSYRIRVMSRTLYCTVMK
>NZ_LT854705.1|WP_057731078.1|809327_809861_+|GNAT-family-N-acetyltransferase
MSEDVAIRLPGAADAAQLLTLLERLQQESDTFTLADADDPISVDQEGEQIEQIKRSPAHLLLVASLGDQLIGVLSVSPTHEGNVGELGVAVEQAYWHQGIGTALVDEALYWAETASSLAAVGLIVQTRNVAAVKLYTKLGFTRTKTPPETVTDDAGNQVTAVEMVYPLNDQGLADED
>NZ_LT854705.1|WP_087741700.1|808858_809335_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE
MLELTVTSPEMTMALGKQLAPGLQAPDVILLDGDLGAGKTTFTKGLAAGLGIKRNVKSPTFTIIREYQGGRLPLYHMDVYRLEDGSGDELGLEEYFNGDGVNVVEWSQFIADELPEHYLRIVFKRDDDASETQRTLTFEPHGDHFERLVEDLEAIHHE
>NZ_LT854705.1|WP_087741699.1|807688_808666_+|phosphate-acetyltransferase
MELFDSLKQKINGKNKTIVFPEGADKRVLGAASRLAHDGLIKAIVLGKQAEIDATAKANDIDLSQLTLLDPENIPADQHKAMLDALVERRHGKNTPEQAAEMLKDPNYIGTMMVYMDQADGMVSGAIHATGDTVRPALQIIKTKEGVRRISGAFIMQKGDQRYVFADCAINIELDAAGMAEVAVESAHTAKVFDIDPKVALLSFSTKGSAKGDMVTKVQEATKIAHETSPDLAVDGELQFDAAFVPTVAAQKAPGSDVAGHANVFVFPELQSGNIGYKIAQRFGGFEAIGPILQGLNKPVSDLSRGCNEEDVYKVAIITAAQALN
>NZ_LT854705.1|WP_057731083.1|806927_807641_+|uracil-DNA-glycosylase
MKPFIHNDWWPVLEPEFEQDYYQNLRKFLVDEYQHYRIDPDMYHIFTAFDWTPFSQVKVVILGQDPYHNPGQAHGCSFSVMPGTKIPPSLLNIYKELQTDVGCTPVNHGYLKKWADQGVLLLNSVLTVRDGAAFSHKGHGWERLTDAAIRKLSERAEPVVFILWGRAAQDKIALIDTKTNIVLKSAHPSPLSANRGFFGSRPFSKTNIALTSLGETPIDWQLPATVSADDASQSNHA
>NZ_LT854705.1|WP_087741240.1|804790_806053_-|ISL3-family-transposase
MSQDQSTRVLLQIKDENIKNLSTKILSDGVMRVMGELTYNSILCPRCGKVTMNHNGHKTVTVRLPRVSERTTLLVLKKQRFRCQNCGKTLLAQTPLIRKQHQISENTLHAIDLALTEDRTMSSIATQYNVSTNTVCRRLTLLGKELQPAYNGLPRQLCIDEFRSTGNQMSFIAINAKTHDIVTILSGRKNADIKHFFRSHYSNKNRKHVKSVVMDFNSQYESAIRTLFPNAKLVADNFHLVQMTLRSLNQTRVQLMKQFKPDTREYRILKFYWRFYLKSYDSLEATKVWWFSHLKDRQTQEQLVQEGLGLSEQFMHTYFSAHQLVKAFQDRDYTGFLKALGGVENVSPQLMTTVKTFIHRKRLIKNMAHGTLSNGPIEGINRKIKQIKRTAYGYKNWKHFIYRIRIEFLIKVKKKNPIRK
>NZ_LT854705.1|WP_057731069.1|816819_817473_-|DUF1361-domain-containing-protein
MNRRAKWEIRGFFILWLLFLFFRAHDPFSFLVLNTFLGYIPIEISFHLGRKRSAWLFWPMVIIWLLFYPNAPYLLTDLFHLSLLQPYAVSGLLRVTPHIWIYFTYLITSALFCAFLGFWSLNFVSQSISERLARGNNIVRLFVVLTLTFLSSVGVYIGRFLRIHTIYLFLNPEQFIRPLMNMWTNDLWIFVILMTFIQLFCYWILHLIMTAQKPTTI
>NZ_LT854705.1|WP_057731068.1|817760_818609_+|TIGR00159-family-protein
MNLNWGNLLTLGNLVNVLDILVVWFVIYELIVMLRGTKAIQLFRGVILILVVKVISSYFGLNTVSWLMDQVINWGVIAVIIIFQPEIRRGLEHLGRGSLFVRMRHENEAANRMIAGLDKAIQYMSKRRIGALMTIQQDTGLEDYIETGIKLDAELTGELLINIFIPNTPLHDGAVIIRNNRIAVAAAYLPLSESNLIPKELGTRHRAAVGISEVTDALTIVISEETGEVSITKNNELLRGLTQEDYLKFLKHELVNEEAATNHNILETALDWIDQRLHRGRR
>NZ_LT854705.1|WP_087741702.1|818608_819571_+|cell-surface-protein
MKNQHYTAWIYRILALILAILLFFYVNSTQSSSSQQTTNSGKTSLTATKTMTVSVPLQLNVNSNKYFVTGYPEKVKVTLRGPLALVTTTANTQNFKVYASLSDLGTGKHKVSLHQEGLNHEIESSISPAKITVDIEPRRTVSFPVKVRFNQQNIASGYTAGKPTTDVTNVKATGAANEISRVSQVIAQLSVPQNTKKTVNSQAVIGALDKQGKTVNVILTPSTTTVNLPITKGASKTVNVKLNVKNGSSGTTYKLSSSTTKVKAFGSAAQLKALSTAQVDVDVSDVKSTATKTVTLDTNDNEVTAFDPATIRVTVKATAN
>NZ_LT854705.1|WP_087741703.1|819609_820968_+|phosphoglucosamine-mutase
MKYFGTDGVRGVANQELTPELAFKVGRYGGYVLTQHADSENKHPQVLVARDTRISGQLLENALVAGLLSVGIEVLRLGVITTPAVAYLVRTQGAAAGVMITASHNPAEYNGIKYFGNDGYKLSDDMEEEIEALLDSPTDDQPRPSTDGLGTVEDYSEGSQKYIQFLEQTISDDLAGLHIAVDAANGSTSGLVSRLYADFDLDFDTIATKPNGININDQVGSTHPENLQKFVVEKGAQIGLAFDGDGDRCIAVDENGDIVDGDKIMYICGKYMAEHGRLKKDTIVTTVMSNLGMYKAMEAHGLKSVKTKVGDRYVVEEMLKSGYNLGGEQSGHIVFLDFNTTGDGLLTSLQLLHILKASGKKLSELAADVTTYPQKLVNIRVADKQAAMDNPQVKAMIATVEKEMNGDGRVLVRPSGTEPLLRVMAEAPTKESVSTYVERIADVVRAEVGVEE
>NZ_LT854705.1|WP_087741704.1|821309_823124_+|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGVTGNDNAVKILVEGLQKLEYRGYDSAGIYVNDQKGNDYLVKTKGRISQLREKITPDVHGSTGIGHTRWATHGVVSVDNAHPHFSNDDRFYLVHNGVIDNFQEIKAQYLSDVPFRSQTDTEVVVQLIDKFAVEDHLDAKSAFLKALSLLKGSYAFLLMDREQPDTLFVAKNKSPLLVGVADGFNVVCSDAMAMLRETHDFLEIMDGEVVTVTPNDVKIQDADGNPVERQTYHVDMNADETDKGTYPFYMLKEVDEQPNVMRKLAQTYLSEHGEPQIDDKLIKAMQAADRLYIIGAGTSYHAGLVGKRLFERLAHIPTEVHVSSEFAYEQPMLADKPFFIFLTQSGETADSREVLVNVNDAGYPSLTITNVQNSTLSREASYTLLLHAGPEIAVASTKAYTAQIALEAILAKALGEVNGQIVAQNFNIRQQLGLVATGMQAIVDEKAKIEDLANNYLMKSNRAFYIGRGIDHAVSLEAALKLKEISYVQAEGFASGELKHGTIALIEKDTPVIGFITQSKTAGLTRSNLQETMARGAKTMTIVREGLAIDGDTLVLPDVDEMLMPLLTVVPAQLLAYYTSLNKGLDVDKPRNLAKSVTVE
>NZ_LT854705.1|WP_087741233.1|823342_823798_+|IS200/IS605-family-transposase
MANKLNSLAHTKWLCKYHIVFTPKYRRKIIYNQYRRDLQEYIKLLCKYKGVTIIEGHMMPDHVHLLVSIPPKLSVSSFMGYLKGKSALMMFDRHANLKYKFGNRHFWSEGYYVTTVGMNEATIKKYIQDQEKHDMVLDKLTTKEYTDPFKG
>NZ_LT854705.1|WP_087741705.1|824342_827666_+|SEC10/PgrA-surface-exclusion-domain-containing-protein
MTKVKKIVAGVATVAGVLAFSGQAAHADATPAKTAAPATGEQTKQDTLAEQVEKAPNVVAAKDNAAKAGQTTTAAQSTATDAQTQAATATDQNQTATQAQSAAQAKVDAAQKLVDQTSAAQQVAQTAKDQAAATAAAQDGVVKTDQAAVDAAAQKQQDAQTAYDQAKTAATNATPENIQNTKNQVSQTSDKVAKDQATEKQDSADLTAAQTKQTAAQKAADDATAQAKTDKNTVDQDQTAASDAAKKVTQDQTSLDAAQQNLNTAKTAKTAADNQVTTSQKAVNATTQQIAAQQKILDETATTSSAAAQAQTAAEDAVARYKALTISANAAQARVNEFNANNKTSITNTLTLPDGVKDLLANYTTAKDKYMADVAANTMSPTELTAEKTALDASGQTLQTALSQGITMNTFQADPADAQDTFTDINNLSDDLIKQLSQFTSNLLNQVRTQLGNNPTSVTLGAMNFAKNVAQDYTADNWSVDQGHNDDAIKKEAQASGLNDGGNYYESLASTTLPQDTNNLGQLKEAVYNSLKQMLFADNDNGNMFGHTIALTGQSAPTDNAFIGVAFDGLHQAHFEIIPNNSAYIPAGSTFDQTAPQARTLGEDAAYKFSLLTPAYNDQTQAQTDLNTAKTADAANVTARKNAQDQLTTLNTQLASQKAQLATDTDVQTKANADVTAQQAKVDELTKTLATDQQAATDAQKALTAAQAKAATSQTAATTAAKALTDANTRVNDLTTKLAQDQDTTKTDTTKLNELNATLADYQKSAQTLNTAKTNLDTTNQDLQTAKDKLAADQKVQAQDAQDLETKTQALAAATKAYQDALAALKAAEAELANAKTNATATAATLAAATQKVKAAQAALAAAQTAQQQADAQVPIERAKALQALLDAAKPTTPVTPTDPTKPTTPVTPTKPTEPTTPVTPTKPTEPTTPVTPTKPTEPTTPVTPTEPTTPTTPTTPVTPTEPTVPTTSTATPISQPVTAPTTATKADQSTRTTKPATKKATKKATKKAPTHDLAAAKQQVAKAARGRYASGQANVVQTTATGQGHGKTVLTMTPADKTTNQQVVLPGLANKHTTLPQTGEQAPAGLSLLGLLLGVFGLTAWRRQRN
>NZ_LT854705.1|WP_172825269.1|828132_828837_+|6-phosphogluconolactonase
MHVQIVKDQAAGGKAGFQIFQQALTAGAKVLGLATGSTPISIYQQLVASDLDFSQLTSVNLDEYVGLGPDHPQSYRYFMQQHLFNAKPFAHFYVPDGLNADAAAETKRYDDIIAANPIDLQLLGLGRNGHVGFNEPGTDEHSTTHKVALTQSTIDANARFFDNEDEVPRYAYSMGIGSILQAKEILIVAYGEAKAAAVAAMLQGPVTPDVPASFLQTHPNVHVILDEAAASQLK
>NZ_LT854705.1|WP_087741707.1|828933_830364_+|glucosaminidase-domain-containing-protein
MKGSKQWLIAVAIIGVGLGSAVGVTSHAATTQQTFISKLKSPVKTVANQYKLYPSVMMAQAALESAWGTSQLTLQANNYFGIKGSYNGQSVSMETSEYDANGKLYTTSANFRKYPNAKASMTDNAKLLRNGLSYNTAYYSGTWRENAATYEAAANALTGTYATSPHYGASLISLIQQYDLASLDKKASTTTSSSSSAASSSSSASTVQPVTYATAKYYGASGTQTARLSSKYTSYRAYNHIKGTREKVTKTAWSKLKVGTGQLVYLNMWGVKKDPTTGKKTTWYRVTLSPAKSAKKYWVYRSALTLPTVKYTMGKATVKLSTTSGDYYNHVFNSPYLAKSQGALSQLTAKSYTADQQAVKTQDGVKSTWYRIGVAKAKYWVAADRTTASPQYDYVAYTKTTGTRTLSKKYTKYHVYNHVKKTHFNQQELKWPSQAKVGTKVTFDQIGTKPAYKTTWYRIQFSGDKTKYWVAARALN
>NZ_LT854705.1|WP_057732069.1|830567_831653_+|ABC-transporter-ATP-binding-protein
MDNAYKIKVQNVTKEYDLYKSQSEKLRSFFSLRNSKVPHFWSLMGISLEVKPGETLGLIGVNGSGKSTLSNIISGIIPQTTGVVDVRGDTSIIAIGAGLRGNLTGLENIRLKALMQGLTNPEIDALMDDIVSFADIGDFLYQPVKSYSSGMKSRLGFSIAVHVNPDILIIDEALSVGDDTFYQKCVDKIAEFKDEGKTIIFVSHSLKQIEILCDRVAWIHYGTLKEIGDTASVVKDYRGFTKWFKAQTKKEKKHFQRQMKANQKAFDIDAYQKEVTDERQKAEPDNANVASEVKKDFYGSVISEKMSVGNRILTTAVGILFVLVCLVNVSGHSVGDVIQHPSNLVHPETVLHDANATNTVK

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Crispr_ID: NZ_LT854705_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT854705_4

845372-845522

Orphan

I-E,II-B

Consensus_repeat	Method
GTATTCCCCACACGTGTGGGGGTGATTC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_LT854705_4

>merge|NZ_LT854705|4|845372-845522|CRISPRCasFinder
GTATTCCCCACACGTGTGGGGGTGATTCTCCCCGGCCTTAATTGCCTTGACCGCTTGACTGAGTATTCCCCACACGTGTGGGGGTGATTCTATCCCCGTCTTCTGGGTCTTCTGTTTCCATGTGTATTCCCCACACGTGTGGGGGTGATTC

>NZ_LT854705|4|4|845372-845522|CRISPRCasFinder
GTATTCCCCACACGTGTGGGGGTGATTC	TCCCCGGCCTTAATTGCCTTGACCGCTTGACTGA
GTATTCCCCACACGTGTGGGGGTGATTC	TATCCCCGTCTTCTGGGTCTTCTGTTTCCATGT
GTATTCCCCACACGTGTGGGGGTGATTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT854705.1\|WP_087741721.1\|853052_854312_+\|3-isopropylmalate-dehydratase-large-subunit	unknown	unknown	gnl\|CDD\|234748
NZ_LT854705.1\|WP_087741713.1\|844020_844479_-\|OsmC-family-protein	unknown	unknown	gnl\|CDD\|376823
NZ_LT854705.1\|WP_087741720.1\|852018_852942_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_LT854705.1\|WP_087741711.1\|841080_841422_-\|LicD-family-protein	unknown	unknown	gnl\|CDD\|368225
NZ_LT854705.1\|WP_057732046.1\|845952_846324_-\|DUF1304-domain-containing-protein	unknown	unknown	gnl\|CDD\|377753
NZ_LT854705.1\|WP_087741718.1\|849472_850258_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_087741717.1\|848766_849486_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_LT854705.1\|WP_057732058.1\|837170_839339_-\|RNA-degradosome-polyphosphate-kinase	unknown	unknown	gnl\|CDD\|235469
NZ_LT854705.1\|WP_087741710.1\|835592_836153_+\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
NZ_LT854705.1\|WP_087741887.1\|841505_842522_-\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_LT854705.1\|WP_057732060.1\|836247_837174_-\|exopolyphosphatase	unknown	unknown	gnl\|CDD\|274735
NZ_LT854705.1\|WP_087741714.1\|844848_845031_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_170218388.1\|843802_843976_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_087741719.1\|850312_850996_-\|LysM-peptidoglycan-binding-domain-containing-C40-family-peptidase	unknown	unknown	gnl\|CDD\|366353
NZ_LT854705.1\|WP_087741722.1\|854311_854830_+\|3-isopropylmalate-dehydratase	unknown	unknown	gnl\|CDD\|234762
NZ_LT854705.1\|WP_087741715.1\|846535_847030_+\|alcohol-dehydrogenase	unknown	unknown	unknown
NZ_LT854705.1\|WP_087741712.1\|843320_843773_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_LT854705.1\|WP_057732056.1\|839335_840868_-\|exopolyphosphatase	unknown	unknown	gnl\|CDD\|223326
NZ_LT854705.1\|WP_057732043.1\|847183_847558_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224639
NZ_LT854705.1\|WP_087741716.1\|847645_848671_-\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382

Protein	Function_ID	Function_description	E-value
NZ_LT854705.1\|WP_087741721.1\|853052_854312_+\|3-isopropylmalate-dehydratase-large-subunit	gnl\|CDD\|234748	PRK00402, PRK00402, 3-isopropylmalate dehydratase large subunit; Reviewed.	0
NZ_LT854705.1\|WP_087741713.1\|844020_844479_-\|OsmC-family-protein	gnl\|CDD\|376823	pfam02566, OsmC, OsmC-like protein. Osmotically inducible protein C (OsmC) is a stress -induced protein found in E. Coli. This family also contains a organic hydroperoxide detoxification protein that has a novel pattern of oxidative stress regulation.	8.72543e-16
NZ_LT854705.1\|WP_087741720.1\|852018_852942_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.17062e-37
NZ_LT854705.1\|WP_087741711.1\|841080_841422_-\|LicD-family-protein	gnl\|CDD\|368225	pfam04991, LicD, LicD family. The LICD family of proteins show high sequence similarity and are involved in phosphorylcholine metabolism. There is evidence to show that LicD2 mutants have a reduced ability to take up choline, have decreased ability to adhere to host cells and are less virulent. These proteins are part of the nucleotidyltransferase superfamily.	7.82457e-09
NZ_LT854705.1\|WP_087741717.1\|848766_849486_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.74512e-43
NZ_LT854705.1\|WP_057732058.1\|837170_839339_-\|RNA-degradosome-polyphosphate-kinase	gnl\|CDD\|235469	PRK05443, PRK05443, polyphosphate kinase; Provisional.	0
NZ_LT854705.1\|WP_087741710.1\|835592_836153_+\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	3.46167e-89
NZ_LT854705.1\|WP_087741887.1\|841505_842522_-\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	8.09877e-67
NZ_LT854705.1\|WP_057732060.1\|836247_837174_-\|exopolyphosphatase	gnl\|CDD\|274735	TIGR03706, exo_poly_only, exopolyphosphatase. It appears that a single enzyme may act as both exopolyphosphatase (Ppx) and guanosine pentaphosphate phosphohydrolase (GppA) in a number of species. Members of the seed alignment use to define this exception-level model are encoded adjacent to a polyphosphate kinase 1 gene, and the trusted cutoff is set high enough (425) that no genome has a second hit. Therefore all members may be presumed to at least share exopolyphospatase activity, and may lack GppA activity. GppA acts in the stringent response. [Central intermediary metabolism, Phosphorus compounds].	1.30182e-111
NZ_LT854705.1\|WP_057732046.1\|845952_846324_-\|DUF1304-domain-containing-protein	gnl\|CDD\|377753	pfam06993, DUF1304, Protein of unknown function (DUF1304). This family consists of several hypothetical bacterial proteins of around 120 residues in length. The function of this family is unknown.	1.27778e-24
NZ_LT854705.1\|WP_087741719.1\|850312_850996_-\|LysM-peptidoglycan-binding-domain-containing-C40-family-peptidase	gnl\|CDD\|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	6.22174e-21
NZ_LT854705.1\|WP_087741722.1\|854311_854830_+\|3-isopropylmalate-dehydratase	gnl\|CDD\|234762	PRK00439, leuD, 3-isopropylmalate dehydratase small subunit; Reviewed.	1.50458e-70
NZ_LT854705.1\|WP_087741712.1\|843320_843773_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	7.25261e-14
NZ_LT854705.1\|WP_057732056.1\|839335_840868_-\|exopolyphosphatase	gnl\|CDD\|223326	COG0248, GppA, Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism].	7.35332e-22
NZ_LT854705.1\|WP_057732043.1\|847183_847558_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|224639	COG1725, COG1725, Predicted transcriptional regulators [Transcription].	3.415e-31
NZ_LT854705.1\|WP_087741716.1\|847645_848671_-\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	2.98261e-70

>NZ_LT854705.1|WP_087741714.1|844848_845031_+|hypothetical-protein
MLDNQLSEEKRKFQMITWRAQKHGAQVVVEERMRQFTATIAEQEAIMLAAQTRRAVVPVG
>NZ_LT854705.1|WP_087741713.1|844020_844479_-|OsmC-family-protein
MSIDREKFPPLYRTVAINDDGLNSHSYVPGGLDVVTSSPLSANPGANPEQFLGLALSTCLNATLEAIEKMRHLPHTSQVHTIVEYARDTKGFQFYVTAQIRIPGVDRQTAIAMADLAERRCPVAKLLSGSPNVTVALVDQFSEVEPVTVKAK
>NZ_LT854705.1|WP_170218388.1|843802_843976_+|hypothetical-protein
MSKKRMSDEEAKRWRKIVFMDDDHEDKRPGRHPKSYVYGEAQSKSWWQRLKGRLSHR
>NZ_LT854705.1|WP_087741712.1|843320_843773_+|MarR-family-transcriptional-regulator
MAEQEQPLLDAFIDVYMSSLKYLDEFISEPAKAFHLSFEQYLILREITRHQNVTLMDIASQRQVTRSAISRQIRVLLRQGYLRQQPDENDRRRLYLLATPTGEQAERLIRQRIDHRFQGWLDMYGEDQAQEILNFIRDFSQVTRLKNRDN
>NZ_LT854705.1|WP_087741887.1|841505_842522_-|IS30-family-transposase
MTHSQINTHKHYQQLSLSDRATIQALRATGDTATVIAQKLHRSKATISREITRGSVTQLDSKRHSHQVYLAETAQAIHDRKRDRTGHHAFLKTGRAFFKALTKELTRKPRVHSVDSFVHFYRDQGKSCPSTTTVYRYIDAGLLELDNMTLPKKLRRRVKGYKNAHKRKNKKIYGDSIELRPAAVNDRTGVGHWEGDLVKGIRSADEPALMTLTERYSRTEIIVKIPDYHADTCLKALQDTINDYGAKEFESITFDNGSEFAKLSEIVGTQIYFAHPYSPWERGTNENTNGLLREYFPKGKSLRDVTLVEVQAVQSALNHRPRRILNYLRPCDYYRRMA
>NZ_LT854705.1|WP_087741711.1|841080_841422_-|LicD-family-protein
MKLQSPLDADQLADVQALKDAREMVMTQYQARTDLTQVKNLASQYAYDKEVFSVAQVSDLTTVPFETLTVQVPSDYATILTAMYGDYQALPPKNQRTEKHLERLIMDNQVFTE
>NZ_LT854705.1|WP_057732056.1|839335_840868_-|exopolyphosphatase
MADNYFGAILVNVTSMELSIVNLKTGQQAEHVLSTVAIGENIYNHVDIDLQTVVDAAEALRGFLQIIKDYGVTHYKAWGSQALSSAPNADFIRDQLYVRTGLRLHWLSLSEESFVRNEAIAIHFADYQRLTEKHAAIIGLNSGSTTFSFFDHHELKASPNMKLGPTRAKEVLQNLRTTAPNPVAVLDDYINSKVDDFYRFIPEDLQQATNQVILIGATPLNGFFIPKGQNSYTLSLERFQQFAHEVTAASDQYLMEHLQISEEAIGLVLPEVRLIQKLLTVVHAEQVHLVNLNVLDGLTTNRAIAEGYYRKQDFNKQILGAAYAVAQRYRVEPHHMALVEKFALHLFDQLKPLHHLKARDRLLLHIAAIVHDSGGFIDTHQHYLHSDYVLQQSEILGLSAEETQIIAAVSRYHSARTPGGELDRFRQLGSSKRLAIAKLAAILRLADALDDAHQQTVERISVSVRPTQVIITAFSDDDLELVHWAFMRKAEFFTDVFGLQPVFKQRRVHK
>NZ_LT854705.1|WP_057732058.1|837170_839339_-|RNA-degradosome-polyphosphate-kinase
MTSEFKKTKYYTNRELSWLDFNARVLDEARDKTNPLLERVRFLGITQSNVDEFFMVRVASLAKLAAVNYPKADASGMTAEDQLLAVNAKAHDQVIKQYSTLTRMLLPLLANQDVHLKTPQDLTADQHRFIEHYFNNEISPALTPMAVDSSRPFPFIGNNTLNIALRLHKAGDKHDKRFATVQVPDIFPRTVRLPGGQNDFILLEDVIKTFIGDLFLGYKVQEAANYRVIRDMDLDVAEEDTSDLLKEVKHQLKQREHGSAVRLEVESGISPALQKRLASSIKVPAYAIYSIGGPIDLTFLGKWTKQMTGLDHQRYPKFTSAQTPGMGADDDLFATIRDHDVFVQHPYDSFDAVTNLIKQAASDDEVLAIKMTLYRVSANSPIIKSLGTAAQNGKQVTVLVEVKARFDEENNVHWAQQLEKMGCHVIYGLIGLKTHCKLALIVRREEDGIRRYMHMGTGNYNDVTAHFYTDMGLFTTNTDMGIDASNIFNMLSGYSEPPYFHQLHMSPDGIREFLVSRINEEINNARLGQPAWIKMKMNSLSDSAMIAKLYEASHAGVHIQLIVRGICCLNVGIPDVSDHIEVHSIVGRFLEHSRIYAFANGGDEQVYLSSADLMTRNLNRRVELLFPILHADLRHRIFDIFHTMWDDNVKTRVLQADREFTRVDRRGLEPLDAQTAFMQAAEAKTKQLPQDTDQPVGAPRQFRPMLSPKNQPKSPMDRSPQQ
>NZ_LT854705.1|WP_057732060.1|836247_837174_-|exopolyphosphatase
MKNLVVIDLGSNSVRMTITEVDNHGNYQTVNQIKRYVRLSANMGPEKVLQPDAIDRTLAALSDFKDVYSQLEKPDIHAVATAAVRQASNQKAFLKQVKEQLGLSLKVISGATEARYDYLGVINTLPMVNGLIVDTGGGSSELILVQNQQLKHVVSIPLGSVTLSQNYLEADVVESASLFKAMTFVNNVFNDVWWLREATNLPIIGLGGANRTLAKINRRKKNFLNAEDVHGYKLTDEDVYETLTQLLGLDLEGRKKVPGLAKERADIIVGGLIPVTLLMRLLDSQQITFSNAGLRDGILFEYLNDLKA
>NZ_LT854705.1|WP_087741710.1|835592_836153_+|sugar-O-acetyltransferase
MEELEKLKAGDWYDFRDPAVAQRKARAAQLCQEFNAIPATAPDQQTAKIREIFGSTGQRVSVQATFNCDYGKNIHVGEDFLSNYNLTILDIAPVTFGHNVMVGPNVDIYTVNHPLTPAGRRGYLAKAQPVTIGNDVWIGGKVTINPGVTIGNNVVIASGAVVTHDVPDNVLVGGVPAKVIRSLAEK
>NZ_LT854705.1|WP_057732046.1|845952_846324_-|DUF1304-domain-containing-protein
MTILITSLTILVAVEHLGIMALEIWGSPAQQAKAFGMPLSFVQQQPAQTALANQGIYNGMLGIVILASQWLLTGTAQHLTTALLLLYIVVVALFGSLTVKRTIFWLQGFPALLTLLLLLGWWL
>NZ_LT854705.1|WP_087741715.1|846535_847030_+|alcohol-dehydrogenase
MRLLDLSGQQFGRLTVIRRDGTAKNGNATWLCKCSCGQLVTVDSYRLRHGITVSCGCYRRDISKARLTQDPRTRKQIGNATNLPLVNGSNVAALTKLSSRNISGVIGVSFDKRSGKWAARLFYHGHYVLNQTFSDFYDAVAARKAAEQKLAKQNDINLKVSAEG
>NZ_LT854705.1|WP_057732043.1|847183_847558_+|GntR-family-transcriptional-regulator
MQFDDKVPIYYQIKNYLYHRMVAGELGLGDKLPAVRQLAVDLTVNVNTVQRALREMIAEGYIAPQRGRGNFVTQDAAKIATLKQQLTTTYIQDLYGQLHALKLTDAEIIAEIKAYIQHRGDADD
>NZ_LT854705.1|WP_087741716.1|847645_848671_-|IS30-family-transposase
MTRIKNIISNQYHQLNLAERGRIEALRGLDWSIRRIAKALHRNPSTISRELRRGTTTQINANTRIFEQSYLAETGEAVYRKHRLNSCYRGLFDHCQTFCNALVTALKARPRMHSVDTFVHQFKTNYPGVVCPSTPTVYRYIDDQRLAIRNSDLPAKLRRRVKRPGTKHHRINKKNLGHSIEERPTVVQARQELGHWEGDLVKGKRVESEPALMTLTERVSRLEIIVKLPNYHADTCLKALQNTLYDYGTEYFKTITFDNGAEFSSLSQVAGTDIYFAHPYSPWERGTNENTNGLLREFFPKGRSLVLASLIDIQLAQDALNNRLRRSLNYRCPADLMPELA
>NZ_LT854705.1|WP_087741717.1|848766_849486_+|ABC-transporter-ATP-binding-protein
MHFNFKSRQLNYRKNTKTILTDVNLQIAPGKIVGLLGENGAGKTTLMRLIAGVAKNAKGTIAVHGETREAPRRAFVSFSEALQGFRPADKLSQIRDFYALAYPDFSAKKYLDLITFLQIDDDQKLSTLSKGTREKFIIALTLSREAAVYLLDEPFNGIDSMSRKRIISSIIQWKQDSATMVISDHYVSEIAALLDEVVIIKDHTVCAHKSSDQIRSEFGLGIEAFYESIYEGDIHDDEL
>NZ_LT854705.1|WP_087741718.1|849472_850258_+|hypothetical-protein
MTSFSHAFRVMWRPKFRSMNQLLFFNLIAVVITMLYQIWQLGLANLEMITTVIGWGAVFGFVAFVLLTRQNEQMLVSDTYRLLPTGDTKLYLANLVTSLVALVYVGVVQVVLVLIGTAMTGKTIRNWFQTNVNFQMNAADLRNLALYGTTSVFWAVAIVLWIWVFVNLIHFGTNTISAFLPNVQQRIVKVVLAVILTWVAIRFMSWIAHLESQVYNHFTTVSDITLNASGIWLDLLSLFVAIAVVAALNIFMMKRWVEAKY
>NZ_LT854705.1|WP_087741719.1|850312_850996_-|LysM-peptidoglycan-binding-domain-containing-C40-family-peptidase
MIKAFTKSILLGSLSAAALLMSGAQASASTVRVQAGNTVWSLAQQHHVSVNAIVSANQLANANRIYVNQKLTIPDGQTTSAATTSGATAHHSATTTTTSSPKTTTSSTTTASASTGGGIATALKIANSNVPYVYGGSSMSGFDCSGLVQYALGLSARTTYQQTKLGTHHYDVANAPAGAILFWGSDSAPYHDAISLGNGKYVAAQNETDGIGVFSQSVWQPSYYIVL
>NZ_LT854705.1|WP_087741720.1|852018_852942_-|LysR-family-transcriptional-regulator
MGQFQSYFYEIYQTGNLTQAAKNLYLSQPALSISLAKLERRLGVTLFDRSQKPLALTAEGQLYLQEVLKVRNAEADFRHELADLQGQTTGEIRIGSSQYFNSYYLPDVLLAYERQYPRVTVRILERNSELLNRELYAGNVDLIVHCGHVDTRKVTVQPVLVDQVVLAIPKALITLDQAHQLRSFIQGASQPDVIAWLEQLPFISVSPTNNFRERMDLICAALSFRPHVKYEMYQLETAFHLAAHGLGATFVTDQIRQSIANHDLYYFDLELPLAQRTFFALTRKRGYLERPLQNFLTTLMDPPAPTR
>NZ_LT854705.1|WP_087741721.1|853052_854312_+|3-isopropylmalate-dehydratase-large-subunit
MHAIEKLLAAKAGVDRVHAGQIVNCDVDVAGINDLYYQTVKSFVEMGGQRVKHPDDVLIFFDHYAPCATVIQAEDHKKFRQFAHEQGIANLMDVNQGVCHQVVVDRGLAKPGEIVVITDSHSTMHGALGAFGTGVGATDLATILITGKLWFKVPEVIKITLTGHLHPGVYAKDVILHILGDLKADHGIYKAIEFAGPALKDMTISERLALCNMTTEMGAATSYIQPDDRTRAFLKAKGVTDYTVYTTDEDYHYQEEITYDVGQIGPQVAAPADVDNVHDLSDYQGVHVDQAYIGSCTGGRLQDFATAAKILKGHHIAPDTRLIIVPASGEVTRECIARGYIQDLLDAGATLSPSGCAACIGIHQGLIAADEVCMSTSNRNFPGRMGSLKGQIYLASPAATATAALTGQITDPRDYVEAE
>NZ_LT854705.1|WP_087741722.1|854311_854830_+|3-isopropylmalate-dehydratase
MKTLRTGHAHVFGQNIDTDQIYPARFIEYTEEADIKKYAMAGSDDPDFVRETQPGDFIVAGTNFGCGSSREHAAITLKGNQVGAIVAESFARIFFRNAINLGLPVITCPHVHAHVQPGDQLQLDLKAGEFKNLTNGWTAPVEPLDDYIMNILSHGGIKPLMRAMTSQGKVRE

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Crispr_ID: NZ_LT854705_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT854705_5

901606-901938

Orphan

I-E,II-B:NA

Consensus_repeat	Method
GNGTTCCCCACAGGTNTGGGGGTGATTC	CRT
GTTCCCCACAGGTGTGGGGGTGATTC	PILER-CR
GTTCCCCACAGGTATGGGGGTGATTCTA	CRISPRCasFinder

5 spacers

The CRISPR arrays of NZ_LT854705_5

>merge|NZ_LT854705|5|901606-901938|CRT,PILER-CR,CRISPRCasFinder
CAGTTCCCCACAGGTATGGGGGTGATTCTAAGCTTCATCCTGCAGGTCCGAAATGTAATCAGTGTTCCCCACAGGTATGGGGGTGATTCTATCATCAGCCATTTCTAACCATTGAGTTGTTCGTGTTCCCCACAGGTGTGGGGGTGATTCCTAACCCGGGTACGCTACACACGTCTTTTAAGCGTGTTCCCCACAGGTGTGGGGGTGATTCCACGCAATTCACGTTTATTTTTGGTGAAGGTCAGCGTTCCCCACAGGTGTGGAGGTGATTCTGATACAATTAACACGGCGTGACCTAGCGTCCTGTGTTCCCCACAGGCGTGGGGTGTCCGT

>NZ_LT854705|5|3|901606-901938|CRT
CAGTTCCCCACAGGTATGGGGGTGATTC	TAAGCTTCATCCTGCAGGTCCGAAATGTAATCA
GTGTTCCCCACAGGTATGGGGGTGATTC	TATCATCAGCCATTTCTAACCATTGAGTTGTTC
GTGTTCCCCACAGGTGTGGGGGTGATTC	CTAACCCGGGTACGCTACACACGTCTTTTAAGC
GTGTTCCCCACAGGTGTGGGGGTGATTC	CACGCAATTCACGTTTATTTTTGGTGAAGGTCA
GCGTTCCCCACAGGTGTGGAGGTGATTC	TGATACAATTAACACGGCGTGACCTAGCGTCCT
GTGTTCCCCACAGGCGTGGGGTGTCCGT

>NZ_LT854705|5|3|901608-901877|PILER-CR
GTTCCCCACAGGTATGGGGGTGATTC	TAAGCTTCATCCTGCAGGTCCGAAATGTAATCAGT
GTTCCCCACAGGTATGGGGGTGATTC	TATCATCAGCCATTTCTAACCATTGAGTTGTTCGT
GTTCCCCACAGGTGTGGGGGTGATTC	CTAACCCGGGTACGCTACACACGTCTTTTAAGCGT
GTTCCCCACAGGTGTGGGGGTGATTC	CACGCAATTCACGTTTATTTTTGGTGAAGGTCAGC
GTTCCCCACAGGTGTGGAGGTGATTC

>NZ_LT854705|5|5|901608-901879|CRISPRCasFinder
GTTCCCCACAGGTATGGGGGTGATTCTA	AGCTTCATCCTGCAGGTCCGAAATGTAATCAGT
GTTCCCCACAGGTATGGGGGTGATTCTA	TCATCAGCCATTTCTAACCATTGAGTTGTTCGT
GTTCCCCACAGGTGTGGGGGTGATTCCT	AACCCGGGTACGCTACACACGTCTTTTAAGCGT
GTTCCCCACAGGTGTGGGGGTGATTCCA	CGCAATTCACGTTTATTTTTGGTGAAGGTCAGC
GTTCCCCACAGGTGTGGAGGTGATTCTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT854705.1\|WP_057731888.1\|912669_914097_+\|gamma-glutamylcysteine-synthetase	unknown	unknown	gnl\|CDD\|179427
NZ_LT854705.1\|WP_057731898.1\|907049_907739_+\|deoxyribose-phosphate-aldolase	unknown	unknown	gnl\|CDD\|234784
NZ_LT854705.1\|WP_031263932.1\|899535_900273_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|181681
NZ_LT854705.1\|WP_087741747.1\|898987_899356_+\|pyridoxamine-5'-phosphate-oxidase-family-protein	unknown	unknown	gnl\|CDD\|334450
NZ_LT854705.1\|WP_087741744.1\|894749_894941_+\|histidine-kinase	unknown	unknown	unknown
NZ_LT854705.1\|WP_057731892.1\|909752_910703_+\|sugar-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225263
NZ_LT854705.1\|WP_087741752.1\|905831_906695_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381359
NZ_LT854705.1\|WP_057731896.1\|907772_908960_+\|phosphopentomutase	unknown	unknown	gnl\|CDD\|235430
NZ_LT854705.1\|WP_087741743.1\|893142_894513_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|225174
NZ_LT854705.1\|WP_087741742.1\|892043_893048_+\|diacylglycerol-kinase	unknown	unknown	gnl\|CDD\|237282
NZ_LT854705.1\|WP_087741750.1\|903960_904830_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_LT854705.1\|WP_087741748.1\|900282_901503_-\|IS21-family-transposase	unknown	unknown	gnl\|CDD\|226950
NZ_LT854705.1\|WP_087741753.1\|910815_912114_+\|pyrimidine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180387
NZ_LT854705.1\|WP_057731894.1\|908985_909690_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NZ_LT854705.1\|WP_087741745.1\|896174_897104_-\|IS30-like-element-ISLpl1-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_LT854705.1\|WP_087741751.1\|904947_905814_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381359
NZ_LT854705.1\|WP_087741746.1\|897791_898838_-\|NADPH-dehydrogenase	unknown	unknown	gnl\|CDD\|239242
NZ_LT854705.1\|WP_087741749.1\|902299_903622_+\|S-layer-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_010620880.1\|895021_896047_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_LT854705.1\|WP_057731922.1\|890599_892021_+\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	unknown	unknown	gnl\|CDD\|235489

Protein	Function_ID	Function_description	E-value
NZ_LT854705.1\|WP_057731888.1\|912669_914097_+\|gamma-glutamylcysteine-synthetase	gnl\|CDD\|179427	PRK02471, PRK02471, bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB.	9.09015e-88
NZ_LT854705.1\|WP_057731898.1\|907049_907739_+\|deoxyribose-phosphate-aldolase	gnl\|CDD\|234784	PRK00507, PRK00507, deoxyribose-phosphate aldolase; Provisional.	1.20146e-117
NZ_LT854705.1\|WP_031263932.1\|899535_900273_-\|ATP-binding-protein	gnl\|CDD\|181681	PRK09183, PRK09183, transposase/IS protein; Provisional.	7.79955e-71
NZ_LT854705.1\|WP_087741747.1\|898987_899356_+\|pyridoxamine-5'-phosphate-oxidase-family-protein	gnl\|CDD\|334450	pfam01243, Putative_PNPOx, Pyridoxamine 5'-phosphate oxidase. Family of domains with putative PNPOx function. Family members were predicted to encode pyridoxamine 5'-phosphate oxidase, based on sequence similarity. However, there is no experimental data to validate the predicted activity and purified proteins, such as yeast YLR456W and its paralogs, do not possess this activity, nor do they bind to flavin mononucleotide (FMN). To date, the only time functional oxidase activity has been experimentally demonstrated is when the sequences contain both pfam01243 and pfam10590. Moreover, some of the family members that contain both domains have been shown to be involved in phenazine biosynthesis. While some molecular function has been experimentally validated for the proteins containing both domains, the role performed by each domain on its own is unknown.	0.00115918
NZ_LT854705.1\|WP_087741742.1\|892043_893048_+\|diacylglycerol-kinase	gnl\|CDD\|237282	PRK13055, PRK13055, putative lipid kinase; Reviewed.	0
NZ_LT854705.1\|WP_057731892.1\|909752_910703_+\|sugar-binding-transcriptional-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	3.72023e-104
NZ_LT854705.1\|WP_087741752.1\|905831_906695_+\|aldo/keto-reductase	gnl\|CDD\|381359	cd19133, AKR_AKR5F1, the AKR5F family of aldo-keto reductase (AKR). Klebsiella sp. 2,5-diketo-D-gluconic acid reductase (2,5-DKG reductase) is a founding member of aldo-keto reductase family 5 member F1 (AKR5F1). It catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).	2.58129e-153
NZ_LT854705.1\|WP_057731896.1\|907772_908960_+\|phosphopentomutase	gnl\|CDD\|235430	PRK05362, PRK05362, phosphopentomutase; Provisional.	0
NZ_LT854705.1\|WP_087741743.1\|893142_894513_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	6.9435e-179
NZ_LT854705.1\|WP_087741750.1\|903960_904830_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	5.1039e-19
NZ_LT854705.1\|WP_087741748.1\|900282_901503_-\|IS21-family-transposase	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	5.92785e-32
NZ_LT854705.1\|WP_087741753.1\|910815_912114_+\|pyrimidine-nucleoside-phosphorylase	gnl\|CDD\|180387	PRK06078, PRK06078, pyrimidine-nucleoside phosphorylase; Reviewed.	0
NZ_LT854705.1\|WP_057731894.1\|908985_909690_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	9.66147e-148
NZ_LT854705.1\|WP_087741745.1\|896174_897104_-\|IS30-like-element-ISLpl1-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	7.26917e-69
NZ_LT854705.1\|WP_087741751.1\|904947_905814_+\|aldo/keto-reductase	gnl\|CDD\|381359	cd19133, AKR_AKR5F1, the AKR5F family of aldo-keto reductase (AKR). Klebsiella sp. 2,5-diketo-D-gluconic acid reductase (2,5-DKG reductase) is a founding member of aldo-keto reductase family 5 member F1 (AKR5F1). It catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).	1.96566e-160
NZ_LT854705.1\|WP_087741746.1\|897791_898838_-\|NADPH-dehydrogenase	gnl\|CDD\|239242	cd02932, OYE_YqiM_FMN, Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis. Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing agent. The YqjM enzyme exists as a homotetramer that is assembled as a dimer of catalytically dependent dimers, while other OYE members exist only as monomers or dimers. Moreover, the protein displays a shared active site architecture where an arginine finger at the COOH terminus of one monomer extends into the active site of the adjacent monomer and is directly involved in substrate recognition. Another remarkable difference in the binding of the ligand in YqjM is represented by the contribution of the NH2-terminal tyrosine instead of a COOH-terminal tyrosine in OYE and its homologs.	2.1509e-137
NZ_LT854705.1\|WP_010620880.1\|895021_896047_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	3.13227e-72
NZ_LT854705.1\|WP_057731922.1\|890599_892021_+\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	gnl\|CDD\|235489	PRK05477, gatB, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB.	0

>NZ_LT854705.1|WP_087741748.1|900282_901503_-|IS21-family-transposase
MRHDVREGVKQYVNNDIKPNFTALGRQFGVDYRTAKRAYEEAQGSMTLPLIKHKRPSLLDGYRSIIEEKLELHCSAKAIYKFIQKRGFQGKYTIVREYCASIRKERTHKATIRVEHTPGLSAQVDWKEEMTLYDRNGQPHRFNIFLYVLPFSKLKYVTLVFERSQDTLFQCLNDAFEATGGVPSEIWFDNMKQVVDHTKSSFGKAIFNERFRQFSHDAGYNPIACRVFRPQTKGVVEALARTMERLRPYNYEFEDGVELIGLVNDLCEDLNYEVSQATNQVPMDKWQNEEKEYLHEQPANLLNPFFEEDITRIVSKESMVNFRKCKYSVDPRYIGRTVDIELTDNEQRIQIYYNGEMIRSHNITTNQFNYDKQDRVRILGSDLLKGQSEQDIQEYIAEHLSEYDQV
>NZ_LT854705.1|WP_031263932.1|899535_900273_-|ATP-binding-protein
MTSKFQELLTNLESLGLTKMVAYLPEYVDQINQQQLSFTEAMLTLTSTELEWNQEQSIERIVKRAHFPQKKTLKGFDFNFQPSINQQEVVGFQDLAFLEKNENLIFIGSPGVGKTHLAISIGIEACRQGKRTLFINCHELLLRLRTANEKGTLERCINRYARYDLLVIDEIGYLPIDHDEANLFFQLINARYERHSTIITSNSDLSGWVEIFQNPTVTAAILDRLVHHVHVVKITGKSYRLKGVG
>NZ_LT854705.1|WP_087741747.1|898987_899356_+|pyridoxamine-5'-phosphate-oxidase-family-protein
MDQKFLDVIKDETPATIVTINAQPASVVNTWSHYINVVNDQTLLIPSAGMHSIENDFQTDNHVTITIGSHKVEGTQGLGCGYHIHGTGTFETNGANFDRMKAQFDWIRAVLVVTIDDIHQKI
>NZ_LT854705.1|WP_087741746.1|897791_898838_-|NADPH-dehydrogenase
MSKLLEPAHLAKLSLKNRVVMSPMCLYAVTQEDGELTPVHCAHYLTRAMGQVGLIILEATAVTPDGRITKNDLGLWNDAQAVKLRDLVTNLHQLGAKVGVQLNHAGRKAVDAVTPVAPSDQRYSPDYRQPHPLTIPEIHNIVADFRAAAKRATAAGVDVIDIHGAHGYLIDQFLSPVVNQRHDPYGGSLRDRYRFLHEIVTAIREEFSGSLWTRLSLTDYQPSTQQNSLSEWQRVAQWLEADGVDLLDVSTGGLFPLKPNFPVHDGYQTKFATKLKHAVDIPVSTVGLLDNPGLCEYILQNHQADLILEGRALLRNPNWVATADLALHDHNLTRDTFNQSYYRGMNER
>NZ_LT854705.1|WP_087741745.1|896174_897104_-|IS30-like-element-ISLpl1-family-transposase
MSSITYSERIKIETFCELGLSNIQMGVRLNRSPSTISYELSRCQPYQAELAQTDAEYKRSRCGRKTKLSDELKQKILNHLRLSWSPGMIAHEFTLATKSIYNWLNQGRIDFSLNDLPEHGVRQRRNVDQRSKYNQSLGRSIEQRPMMINQRNRIGDFELDTVVGPRGHSKAVLLTLIDRKSRFLWAYRLKDRTTATVNEALTKFLTTFNGPVHSFTVDRGTEFSGLVSLESQYGIKTYYCHAYTPAERGSNERFNRNLRYFYPKGTRFEHISAQDLTTTLLQINQRPLKILDWQTPYQVMLTNLSKNSD
>NZ_LT854705.1|WP_010620880.1|895021_896047_+|IS30-family-transposase
MTRIKNIISNQYHQLSLAERGRIEALRDLDWSIRRIAKVLHRDPSTISRELRRGTTTQINANTRIFEQSYLAETGEAVYRKHRLNSCYRGLFDHCQTFCNALVTALKARPRMHSVDTFVHQFKTNYPGVVCPSTPTVYRYIDDQRLAIRNSDLPAKLRRRVKRPGTKHHRINKKNLGHSIEERPTVVQARQELGHWEGDLVKGKRVESEPALMTLTERVSRLEIIVKLPNYHADTCLKALQNTLYDYGTEYFKTITFDNGAEFSSLSQVEGTDIYFAHPYSPWERGTNENTNGLLREFFPKGRSLALASLVDIQLAQDTLNNRLRRSLNYRCPADLMPELA
>NZ_LT854705.1|WP_087741744.1|894749_894941_+|histidine-kinase
MKVIQYNLTGEVIKRYSSDFNQFEDYPVGEKVRITTTSGQKYVGFWQTFFTPRFKIEVQHLLY
>NZ_LT854705.1|WP_087741743.1|893142_894513_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MKIKAPVTKNKRLDVTIADLTYQGMGVAKVDDFSLFVENALPGEQVTIQVTKVQKHYGFARVVAWQTKSPDRVEDVDKTYRQTGIAPLQHLAYPAQLKFKQHQIAELFNKAHIDVAVAPTLGMAHPTQYRNKAQVPVRTVKGQLETGFYRQHSHELIPLTDFYIQDPEIDKAIVKVRDLLRQFEIPAYDEINDKGVIRNVMVRRGYYSHEMMIVLISRQQKLPSQAQLVEQIHAALPEVTSIILNVNAKRTNVIMGNVTRVLYGKPTIEDTLMGLTFAISSRSFYQVNPQQTEKLYQMAIDKAGLTGNETVIDAYCGIGTISLALAKHAKQVYGVEIVPEAIEDAKINAQKNHLTNVEFAVNKAEDQMAQWQEAGIKPDVIVVDPPRKGLAPSLIDSAAQMGPKKVVYVSCNPATLVRDVAHFQELGYAIDGDIQPVDQFPQTPHVESVTVLKRVD
>NZ_LT854705.1|WP_087741742.1|892043_893048_+|diacylglycerol-kinase
MRKRARVIYNPTSGREALKKDLIDILAVFEQAGYETSAYATTPAPNSAQDEATRAAKAGFELIVAAGGDGTINQVVNGIAGLPHRPKMAIIPAGTTNDYARALHIPREDPLAAAKVVLKDQTIKMDIGQAGDQYFINIAGGGLLTELTYDVPSNLKSIFGYLAYLVKGAELLPQIKPIEMDLTYDGGHFRGQASMFLLALTNSIGGFEQIVPDAALDDGKFTMIIVKTASLPEILRLMGLVLNGGRHINDPHILYVKTNKVTARPVKDRMMINLDGEYGGDAPMKFRNLKQHIEMYANLDAIPDHAVTSETAEMLAAEEKFVKQVQDLPADAEK
>NZ_LT854705.1|WP_057731922.1|890599_892021_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB
MNFETTIGLEVHVELKTNSKIFSPSPVEFGDDPNANTNVIDWGYPGVLPTTNKGVVADGIIAALALHATVEQHTHFDRKNYFYPDNPKAYQITQADKPIGHDGWVEIDIDGVKKKIGIAEMHIEEDAGKNTHERDHSYVDLNRQGTPLIEIVSKPDIASPAEAYAYLEALRQRIQFTGISDVKMEEGSMRVDVNISVRPVGQDKFGTKTELKNLNSFNYVKRGLEYEEKRQQQVLMSGGSVRQETRRFDEKTGETILMRVKEGSDDYRYFPEPDLPALSISDDWIKQLDAAMPEMPTDRRHRYVTELGLTDYDAMVITQTKEMSDFFDAMVDLKADPKMAANYLQGDVNAYLNDNQVDLAKTKLTPANLAGMINLISDGTISTKMAKKVFKAVTNGEEPKAFVEKHGLVQLSDPAKLQPIIDDILDQNPQSIEDFNNGKKRAVGYLVGQIMKQTHGQANPQVVNKLLMAALNH
>NZ_LT854705.1|WP_087741749.1|902299_903622_+|S-layer-protein
MKSSLSKSLYLGLAALSFGAVATVATTSTASAKSYATAGAYQSLTTAATSRNVESTGTNALYTKPGTVKGAKVVASKAKMATFASSKSSANYFRAYGVKTTNRGSVYYRVVSMDGKYRGYIYGGKSTSDFAGGIKSASTTTSATMPTQTKNYYLKDTTKNTIWTAPKYTQYKASKVSLYNSAKADKFTVDQAATKTREGSLYYHVTDTSNSAITGWIYAGGLTTTAPSATATSSNSVTVKYVDANYSAVGSAQTWVTSTSDTTEGATLGTSDLSSLNSYITSNVPSGYTVTDSSLTSAKYGSTIQVKVAKAATSKVTFKSEGSSTTDTATITAASLADKAFPSLTTTEQEVFTGDADDTIDISTASVFTSGKLNTLTGATQTDSDGNKTYKVYTFDAKATKTANSNAKYGDGVTAYYTVTTKTGDAPTTSTDTGNTNYVD
>NZ_LT854705.1|WP_087741750.1|903960_904830_-|LysR-family-transcriptional-regulator
MIDNYLLEELVTFAQTGTLAQTAATLNVTQPTVTRGMQKLEDDLGVRLFNRQPNRILLTATGELAAAKAKTLLALNRELVTAVQNFDRSQQRLTLKSTLPGPLLVARKIQAQFPTLQLDDQLLPTDQLSNQLISRAAALVLSDQELLTNTVESRYLGTERLAVNLDQFMYHANQSTVQFKELRGLSFLVLQDIGAWRDIIQDQIPDAQFMYQAQRDAFTKITKYADFPYFSTNLSPLDPNAPTVSQDDNRVRIPISDDIAQMPIYGSYLKEDRDRVAPVLEMMSQAWPQ
>NZ_LT854705.1|WP_087741751.1|904947_905814_+|aldo/keto-reductase
MPIPTTTLNNGVTMPQLGFGVFQVPNLAECETAVTAAIQAGYRLIDTATAYQNEAAVGRAIAKSDVPREELFITSKLWVSDFTYERAQKGIDASLQRLGLDYLDLYLLHQPYGDVMGAWHALEEAYHAGKIRAIGVSNFYADQLKNLELTMNVRPVINQVEVNPWYQQPTEVQFNQDENVRVEAWAPFAEGKHGIFTDPTITKIAQAHGKTTGQVILRWLLQRGITVIPKSVHADRMAENLDVFDFELTTAEMSTLAGLDRQESQFFDHRDPVTIEQIFGSSLRQLHD
>NZ_LT854705.1|WP_087741752.1|905831_906695_+|aldo/keto-reductase
MTTPTIQLNDGHQIPAIGFGTFQIPDDGTTYQAVKDALAAGYRHIDTAVAYFNEDEVGRAVRDSGIPRDQIWVTSKLWLQDFGYEAASRAIDKSLQQLDLDYIDLYLIHQPYGDVPGAWRAMEDAKQAGKLKSIGVSNMTPKIWNQFVPQFATMPSVDQVEFNPYFQQTELRAILKAHDVKLEAWAPLGQGNQNLMHEPMITQLAEKYGKNAGQIILRFENQEGVVVFPKSVHESRIKSNLDIFDFDLTADEVAQLRTLDKGQGRHDPDAPGVKEMLLGAFDVHAND
>NZ_LT854705.1|WP_057731898.1|907049_907739_+|deoxyribose-phosphate-aldolase
MTLTTEQLAKYIDHTNLKADATEASIRQTCEEAKQFNTASVCVNSYWIPFVAEQLKDSTVNPIAVVGFPLGAMATESEIFEATTAIDQGAEEIDMVLNVGEMKSGNFEVVEEDIKGLANAVHAKGKLLKVILETCLLTKDEIVKACQLSEKAGADFVKTSTGFSTAGAKLDDVKLMRETVGDRLGVKASGGIHSKEEALAMIDAGASRLGVSATVAILTGKPAAKKAGY
>NZ_LT854705.1|WP_057731896.1|907772_908960_+|phosphopentomutase
MKFKRIFGLVMDSVGTGAAPDSIKYGDEGADTLGHVGEHFAGKLALPNLAKIGISNLRDTPIEGVPAATDPHAYYGKMQEISAGKDSMDGHWEMMGLPVRKALSTFPNGFPADIIDKLEKFSGRKVIGNRPESGTKIIAELGEQQMKTGDLIVYTSGDSVLQIAAHEEVIPLDELYKICEYARSLVNGPEYLVGRIIARPYVGPDGQHFTRTANRRDFTLEPTDETDLNRLQDAGVHVVGVGKINDIFSGHGIDEGYHNESNMDGMDHVDHVMQEDFTGFCFINLVDFDAMYGHRRNPEGFGNALMDFDKRLGTVMANMHDDDLLMITADHGNDPTYRGTDHTREFVPLVVYSPSFKQGGSLGIRSPFSDFGATVLDNFGVKGNNEGHSFLADLK
>NZ_LT854705.1|WP_057731894.1|908985_909690_+|purine-nucleoside-phosphorylase
MSNHLEAKKGDIADTVLMPGDPLRAKYIAETYLDNPVCYNKVRNAFGYTGTYKGHRISVQGTGMGIPSISIYAHELVTEYGAKKLFRVGTSGGMSPDVHVRDVVLAQAATTDSSIIHNIFGGGIYYAPISDFGLLDNAYHAAKDLNIPVKVGNVLAEDRFYNDEMDRKKLVDYGVIATEMESAALFLIAAKYHVKAMSVLTISNHLITGESTTPEEREKSFDDMIKVALEAAIR
>NZ_LT854705.1|WP_057731892.1|909752_910703_+|sugar-binding-transcriptional-regulator
MTETTDQRIAQGLTVAKLYYQADQSQSQIAQQLGISRPTVSRLLQFARKQGLVRIQIIDPVQDVQTLEQALTDAYHVEVHVVPTQLTATNEVLNTVGQYAARYLESIVAEHDVIGIGWGKTIYAIGQNLQPDTLTGVEVIQLKGSVSYSTEHTYAYESIDAFANAFHAMPQYLPLPVIFDHQQTKELVEAERHIQYLLQLGEKANIAIYSAGTVRNTALVFQLGYLQDKEKHYLQQHAVGDIFSRYIDENGEIVDTELNQRTIGIELDSLRHKDHSILVAAGDAKVPAVQAALRGGYPNCLIIDQHAAAELLKATT
>NZ_LT854705.1|WP_087741753.1|910815_912114_+|pyrimidine-nucleoside-phosphorylase
MRMVDIIDKKRNGGELTKEEIQTFVDGVVSGEIPDYQTSAFLMATYFKDMTDAERSELTMAMMKSGDHLDLSSIDGIKADKHSTGGVGDKTSIPLAPIVAALGIPVPMISGRGLGHTGGTLDKLEAIPGYTVEISEKDFLKQVQDVKCAIVGATGNIAPADKKIYALRDVTDTVDSIPLIASSIMSKKIASGTDALVIDVKTGSGAFMKTLDDSRELAHALVEIGKGVGMDCMAIISDMNQPLGNAIGNALEIKESIDILKGNGPKDITDLVLTLGAHMVVMAKKADNLDDARKMCEQTITDGSALKKFGDMVAAQGGDRNVVDHPEIMPQAKFKIDLPAQKAGVVSKVAADEMGIASMLLGGGRQKADDKLDYAVGIMMNKKIGDQVKEGEPLLTIYSDREDVDDIKKLLYDNIEISDHAEPVTLIHETIR
>NZ_LT854705.1|WP_057731888.1|912669_914097_+|gamma-glutamylcysteine-synthetase
MLENLLAVIREENLSEQLYHSLVGIKLTEHRVDQHGHLSRRPQPRAWANRPHHPYLREGKRPSQVTLVTEPNPNIGGILDRLDTLQTVAYRSLEGDDRIWPLSLPPKIDAAELASAGAGHQTDWLTGVKISYSLPDPVIHRLYSHYTADFDSVVAFKNELYFRVAQNFVRYQWLLTYLFGATPMAEPGFLDTLPELPQRPVRSLRYCGALPAGTPVTYTSLGAHLGALQRLAAAGDSAPAGPVTLKGQPTPQDFLTGGIGYLEFNGFDNTPFTANGVSRHALYFLKTFMIYLLVTPLPTTNLAAVLTAARQQNIAVALEQPDQPTQFQTAGEEIFHAMKTMAQDLHAHTEQWGAIDDLGEVLTHPELTPAAKIMTRVDQHSLMDYGLRVANAWRYQRLNSVALLPVYKDLNFRCQHFILMAMQAGIQFYQVKDEFGADLLMFTYQGVTQVLQERDTQTKDPRVQLRELFPELPEF

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Crispr_ID: NZ_LT854705_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT854705_6

1224764-1225037

Orphan

I-E,II-B

Consensus_repeat	Method
GTATTCCCCACATGTGTGGGGGTGATTCCG	PILER-CR
GTATTCCCCACATGTGTGGGGGTGATTC	CRISPRCasFinder
GTATTCCCCACATGTGTGGGGGTGATTCCG	CRT

4 spacers

The CRISPR arrays of NZ_LT854705_6

>merge|NZ_LT854705|6|1224764-1225037|PILER-CR,CRISPRCasFinder,CRT
GTATTCCCCACATGTGTGGGGGTGATTCCGACGCGACCAGCGGCCCGCACGAAGAAGCTATGTATTCCCCACATGTGTGGGGGTGATTCCGTGGTAAAATTGCTGGTTCAGTTCGTCGGTAAGTATTCCCCACATGTGTGGGGGTGATTCTGCTTGATGGTGGGTCGGCTAAAGGGACTAAGGGTATTCCCCACATGTGTGGGGGTGATTCCGGCCATGAACGCTTCCTGTGGAATATCCACGCGTATTCCCTACACGTGTGGGGGTAAACCCT

>NZ_LT854705|6|4|1224764-1224976|PILER-CR
GTATTCCCCACATGTGTGGGGGTGATTCCG	ACGCGACCAGCGGCCCGCACGAAGAAGCTAT
GTATTCCCCACATGTGTGGGGGTGATTCCG	TGGTAAAATTGCTGGTTCAGTTCGTCGGTAA
GTATTCCCCACATGTGTGGGGGTGATTCTG	CTTGATGGTGGGTCGGCTAAAGGGACTAAGG
GTATTCCCCACATGTGTGGGGGTGATTCCG

>NZ_LT854705|6|6|1224764-1225035|CRISPRCasFinder
GTATTCCCCACATGTGTGGGGGTGATTC	CGACGCGACCAGCGGCCCGCACGAAGAAGCTAT
GTATTCCCCACATGTGTGGGGGTGATTC	CGTGGTAAAATTGCTGGTTCAGTTCGTCGGTAA
GTATTCCCCACATGTGTGGGGGTGATTC	TGCTTGATGGTGGGTCGGCTAAAGGGACTAAGG
GTATTCCCCACATGTGTGGGGGTGATTC	CGGCCATGAACGCTTCCTGTGGAATATCCACGC
GTATTCCCTACACGTGTGGGGGTAAACC

>NZ_LT854705|6|4|1224764-1225037|CRT
GTATTCCCCACATGTGTGGGGGTGATTCCG	ACGCGACCAGCGGCCCGCACGAAGAAGCTAT
GTATTCCCCACATGTGTGGGGGTGATTCCG	TGGTAAAATTGCTGGTTCAGTTCGTCGGTAA
GTATTCCCCACATGTGTGGGGGTGATTCTG	CTTGATGGTGGGTCGGCTAAAGGGACTAAGG
GTATTCCCCACATGTGTGGGGGTGATTCCG	GCCATGAACGCTTCCTGTGGAATATCCACGC
GTATTCCCTACACGTGTGGGGGTAAACCCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT854705.1\|WP_087741921.1\|1227900_1228851_+\|50S-ribosomal-protein-L11-methyltransferase	unknown	unknown	gnl\|CDD\|283886
NZ_LT854705.1\|WP_057730755.1\|1221253_1222543_+\|D-alanyl-lipoteichoic-acid-biosynthesis-protein-DltD	unknown	unknown	gnl\|CDD\|274975
NZ_LT854705.1\|WP_057730742.1\|1212876_1213914_+\|heat-inducible-transcriptional-repressor-HrcA	unknown	unknown	gnl\|CDD\|234621
NZ_LT854705.1\|WP_057730749.1\|1218046_1218196_+\|teichoic-acid-D-Ala-incorporation-associated-protein-DltX	unknown	unknown	gnl\|CDD\|372124
NZ_LT854705.1\|WP_087741915.1\|1222663_1224499_+\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_LT854705.1\|WP_087741914.1\|1219762_1220974_+\|D-alanyl-lipoteichoic-acid-biosynthesis-protein-DltB	unknown	unknown	gnl\|CDD\|274974
NZ_LT854705.1\|WP_087741913.1\|1218236_1219763_+\|D-alanine--poly(phosphoribitol)-ligase-subunit-DltA	unknown	unknown	gnl\|CDD\|235313
NZ_LT854705.1\|WP_087741919.1\|1226850_1227117_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_087741912.1\|1216590_1217739_+\|molecular-chaperone-DnaJ	unknown	unknown	gnl\|CDD\|237653
NZ_LT854705.1\|WP_087741924.1\|1230039_1232268_+\|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|223394
NZ_LT854705.1\|WP_057730767.1\|1226243_1226621_-\|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl\|CDD\|234795
NZ_LT854705.1\|WP_087741922.1\|1228854_1229595_+\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	unknown	unknown	gnl\|CDD\|236959
NZ_LT854705.1\|WP_057730754.1\|1221016_1221250_+\|D-alanine--poly(phosphoribitol)-ligase-subunit-DltC	unknown	unknown	gnl\|CDD\|179929
NZ_LT854705.1\|WP_087741920.1\|1227490_1227808_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_057730745.1\|1214573_1216463_+\|molecular-chaperone-DnaK	unknown	unknown	gnl\|CDD\|234715
NZ_LT854705.1\|WP_087741918.1\|1225745_1226111_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_087741917.1\|1225496_1225703_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_087741923.1\|1229674_1230022_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_087741916.1\|1225191_1225461_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_057730743.1\|1213935_1214538_+\|nucleotide-exchange-factor-GrpE	unknown	unknown	gnl\|CDD\|237631

Protein	Function_ID	Function_description	E-value
NZ_LT854705.1\|WP_087741921.1\|1227900_1228851_+\|50S-ribosomal-protein-L11-methyltransferase	gnl\|CDD\|283886	pfam06325, PrmA, Ribosomal protein L11 methyltransferase (PrmA). This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.	1.63357e-103
NZ_LT854705.1\|WP_057730755.1\|1221253_1222543_+\|D-alanyl-lipoteichoic-acid-biosynthesis-protein-DltD	gnl\|CDD\|274975	TIGR04092, hypothetical_protein, D-alanyl-lipoteichoic acid biosynthesis protein DltD. Members of this protein family are DltD, part of the DltABCD system widely distributed in the Firmicutes for D-alanylation of lipoteichoic acids. The most common form of LTA, as in Staphylococcus aureus, has a backbone of polyglycerolphosphate.	5.56781e-180
NZ_LT854705.1\|WP_057730742.1\|1212876_1213914_+\|heat-inducible-transcriptional-repressor-HrcA	gnl\|CDD\|234621	PRK00082, hrcA, heat-inducible transcription repressor; Provisional.	2.15891e-138
NZ_LT854705.1\|WP_057730749.1\|1218046_1218196_+\|teichoic-acid-D-Ala-incorporation-associated-protein-DltX	gnl\|CDD\|372124	pfam12459, DUF3687, D-Ala-teichoic acid biosynthesis protein. This family of proteins is found in bacteria. Proteins in this family are approximately 50 amino acids in length. There are two completely conserved residues (L and Y) that may be functionally important.	3.45834e-15
NZ_LT854705.1\|WP_087741915.1\|1222663_1224499_+\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_LT854705.1\|WP_087741914.1\|1219762_1220974_+\|D-alanyl-lipoteichoic-acid-biosynthesis-protein-DltB	gnl\|CDD\|274974	TIGR04091, hypothetical_protein, D-alanyl-lipoteichoic acid biosynthesis protein DltB. Members of this protein family are DltB, part of a four-gene operon for D-alanyl-lipoteichoic acid biosynthesis that is present in the vast majority of low-GC Gram-positive organisms. This protein may be involved in transport of D-alanine across the plasma membrane. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NZ_LT854705.1\|WP_087741913.1\|1218236_1219763_+\|D-alanine--poly(phosphoribitol)-ligase-subunit-DltA	gnl\|CDD\|235313	PRK04813, PRK04813, D-alanine--poly(phosphoribitol) ligase subunit DltA.	0
NZ_LT854705.1\|WP_087741912.1\|1216590_1217739_+\|molecular-chaperone-DnaJ	gnl\|CDD\|237653	PRK14276, PRK14276, chaperone protein DnaJ; Provisional.	0
NZ_LT854705.1\|WP_087741924.1\|1230039_1232268_+\|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	gnl\|CDD\|223394	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription].	0
NZ_LT854705.1\|WP_057730767.1\|1226243_1226621_-\|large-conductance-mechanosensitive-channel-protein-MscL	gnl\|CDD\|234795	PRK00567, mscL, large-conductance mechanosensitive channel protein MscL.	9.00324e-59
NZ_LT854705.1\|WP_087741922.1\|1228854_1229595_+\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	gnl\|CDD\|236959	PRK11713, PRK11713, 16S ribosomal RNA methyltransferase RsmE; Provisional.	1.81071e-72
NZ_LT854705.1\|WP_057730754.1\|1221016_1221250_+\|D-alanine--poly(phosphoribitol)-ligase-subunit-DltC	gnl\|CDD\|179929	PRK05087, PRK05087, D-alanine--poly(phosphoribitol) ligase subunit DltC.	1.02359e-33
NZ_LT854705.1\|WP_057730745.1\|1214573_1216463_+\|molecular-chaperone-DnaK	gnl\|CDD\|234715	PRK00290, dnaK, molecular chaperone DnaK; Provisional.	0
NZ_LT854705.1\|WP_057730743.1\|1213935_1214538_+\|nucleotide-exchange-factor-GrpE	gnl\|CDD\|237631	PRK14162, PRK14162, heat shock protein GrpE; Provisional.	5.22445e-67

>NZ_LT854705.1|WP_087741915.1|1222663_1224499_+|elongation-factor-4
MDLEKLKQHQKYIRNFSIVAHIDHGKSTLADRILEMTDTVSKRDMQDQILDNMDLERERGITIKLNAVELTYHAKDGHDYEFHLIDTPGHVDFSYEVSRSLAACEGAVLVVDAAQGVEAQTLANVYLALDDNLEIVPVINKIDLPSADPDKVKKEIEDVIGLDASDAVLASAKQGIGIEDLLEQIVAKVPAPSGDLDAPLKALVFDSVYDDYRGVVLSVRVYDGTVQPGDKIRMMNSETEYEVTEVGVNSPNPLSRDYLIAGDVGYITASIKDITETRVGDTVTNAEDPAAKALPGYREMNPMVYAGLYPTDNAKLNDLREALEKLKLNDAALEFEPESSQALGFGFRCGFLGMLHMDVVQERLEREFNLDLITTAPSVTYHAYLTDGTMKEVENPAEMPEASAIKKIEEPIVKATIMAPNEYVGAVMELCQHRRGQFLTMEYLDDYRVNIIYNMPLSEIIFDFFDKLKSSTRGYASLDYEMNGYQESDLVKIDLLLNGDKVDALSFIAHRTFAAQRGREIASRLKGIIPRQNFEIPIQAAIGAKIIARTTIKAYRKDVTAHLYGGDRTRRMKLLEKQKAGKKRMKAVGRVDIPQEAFMAVLKTDEDETKS
>NZ_LT854705.1|WP_057730755.1|1221253_1222543_+|D-alanyl-lipoteichoic-acid-biosynthesis-protein-DltD
MAKRLLRIFGPLILAAILVLAILVSPVTFGFKHVSAGEERQAAVSLSPNVLKGKRIKEAALKENYVPFFGSSEWSRIDPMHPSVLAQKYHRDYRPFLLGARGTQSLTQFFVMQNIQGELRNKKAVFVVSPQWFVKDGTRKDAFAFYYSQLQTAEWLSHYRHDAIDQYAAQRLLQMPVAKSDHFIYAALQRVASGKSLTDYQRFYLRTKMNMLTQEDQFFSGINLPSQNWNKVNQQAKKLPTQYSYAKLDKLAGQIGQEQTGNNRFRISDTFYNQGLKQELKTGKLQGFQRNLSYTQSPEFGDFQLVLDQFARLNTNVMFIIPPVNDRWAKYTGLSQKMLRQFDQKIRYQLQSQGFNNICDLSSKGNVPYFMTDTIHLGWRGWLAVDQKVDPFLTKTQAQPKYRINDKFYSQKWQQLDPTQLAAYEATTK
>NZ_LT854705.1|WP_057730754.1|1221016_1221250_+|D-alanine--poly(phosphoribitol)-ligase-subunit-DltC
MDVKETVLSILSDLTGNDVSGAMDDNLFDSGLLDSMGSVQLLLQLQSQLGVSVPVSEFERSEWDTPNKIVKKVESLA
>NZ_LT854705.1|WP_087741914.1|1219762_1220974_+|D-alanyl-lipoteichoic-acid-biosynthesis-protein-DltB
MLSFEPYGNPTYFALLGVALLPLMIGLLYGKRSRLYETLISIFFLVLTFGGPKWTQGIALIIYILYEVMLTWGYAVYRKQKNSGPVFYLMVILAILPLTVVKVTPAVENGQASLIGFLGISYLTFRAVQTMMETRDGTLKDYQVMTFLQFMLFFPTISSGPIDRYRRFEKDYRSVLDRATYLGMVQKGVRYIFVGFLYKFLLAYYFGSILMPKLQVMAMHSRGGFMDLSWPVLGYMYAYSADLFFDFAGYSLFAVGTSYLMGIATPMNFKQPWRSPNIKDFWNRWHITLSFWFRDFIYMRLVFWFMKHRVFKSPRTTANVTYIINMLVMGFWHGVTWYYITYGLFHGVALVINDAWLRYKKKHRQSVPHNRFTQLFAIFLTANLVCFSFLIFSGFLNTLWFTK
>NZ_LT854705.1|WP_087741913.1|1218236_1219763_+|D-alanine--poly(phosphoribitol)-ligase-subunit-DltA
MIENMITTIDRIATQDPDRLVYDDLGHTNTYGELKQYSDALAAHLDAMQLPREAPILVYGGQTFNMMATFLGIVKSGHAYAPIDTHSPLERITTINDIAHPAAAIAVAALPTDLPGTAVITPDNLQTIFEKPVTDYRVDHAVSGDETYYIIFTSGTTGKPKGVQISHTNLLSYVNWMLSDDFDLPQQPRTLSQAPYSFDLSVMDWGPTLAGGGTLVALPKKVTDNFKELFETLPQMNLNVWVSTPSFMDICLLEPTFDAAHYPDLQRFLFCGEELTHATAQTLHQRFPQARIFNTYGPTETTVAVTQVEITDQILADYPRLPIGYAKDDTTIKVVDDQLNEVPAGTEGEILISGPSMSKGYLNNPEKTAKAFITWHGQQVYRAGDLGVQLENGLIMYRGRTDFQIKLHGYRIELEEVNHYLSQEEHIQVGVAVPKYNRDHKVSQLVAWVVPAAQELSGLALTKAIKENLQGGDMMEYMIPQRFVYKESLPMTPNGKVDIKSIIAEVNQ
>NZ_LT854705.1|WP_057730749.1|1218046_1218196_+|teichoic-acid-D-Ala-incorporation-associated-protein-DltX
MRTKWLAIWHQPVVAFIGWTVFYFAILMALVYLYGYSGLNSTTFIYNEF
>NZ_LT854705.1|WP_087741912.1|1216590_1217739_+|molecular-chaperone-DnaJ
MAQKDLYGVLGVSKDASQDEIKKAYRKLSKKYHPDLNKAPDAAEKFKEVQDAYDVLGDKQKRQNYDQYGSADGAQGGFGGFGGSQAGGFGGGGFGGGGGFDDIFNQFFGGGGQRNPNAPRPGRDLQYQMNLTFEEAIFGKKTKITYTREAQCHTCGGNGAKPGTSPVTCHQCGGSGYVTTVTNTPLGRMQSQQPCPVCHGTGQEIKEKCPTCGGSGHEEQRHEVEVTIPAGVDDGQQMRLQGQGESGTNGGGYGDLFIIFQVTPSKDFRRDGTEIYFDQPISFIQAALGDDVQVKTVHGDVKLKVPAGTQGGTTFRLRGKGAPRLRGNGNGDEHVTVKVVTPKNLNKGQRDALRAFAKASGENVSGTGKGNLFDKMRDKFNE
>NZ_LT854705.1|WP_057730745.1|1214573_1216463_+|molecular-chaperone-DnaK
MASNKIIGIDLGTTNSAVAVLEGSTPKIIANKEGARTTPSVVAFKDGETQVGEVAKRQAITNPNTISSIKSHMGEAGYKVSVDGKDYTPEQISAMILQHLKSFAEDYIGDTVSQAVITVPAYFNDAQRQATKDAGKIAGLDVKRIINEPTAAALAYGLDKQDKDEKIMVYDLGGGTFDVSILDLGDGVFDVLSTNGDTHLGGDDFDQKIMDWLIAGFKEENGVDLSKDKMALQRLKDAAEKAKKDLSGVTEASISLPFISAGANGPLHLEKSLSRAKFNELTADLVEKTRIPVENALKDADLQASDVDVVILNGGSTRIPAVQEAVQKWTGKEPSHSINPDEAVALGAAVQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGNFQLTDIPAAPRGVPQIQVTFDIDKNGIVNVSAKDMGTNKEQKITIKSSDGLSDDEIEKMMKEAKENEAADKQRKEEVDTKNEVDQLLFQTDKTLKEVKGKVSDDEIKKAEDARDALKKAQEANNLDDMKTKKDDLTKIIQDLSVKLYQQAQNAQGGANGAAGAAGAAGAQGTQGNDTNNGGKDDNTVDGDFHEVHDDDNK
>NZ_LT854705.1|WP_057730743.1|1213935_1214538_+|nucleotide-exchange-factor-GrpE
MADKQPESTEAKQAQQATPDQPADGKTQASNAAEQPTTKAEKQATKPDPQAAELAELKQKSSAMEDKYLRAEAEIQNMQTRFQKEQATLIKYDGQQLAKDILPVIDNLERALAVEAKDEAAAGLKKGVQMTYDHLEDALKRNHVTEVAALGQKFDPTLHQAVQTVPASDDQPAETVVQVLQKGYQLKDRVLRPAMVVVAQ
>NZ_LT854705.1|WP_057730742.1|1212876_1213914_+|heat-inducible-transcriptional-repressor-HrcA
MLSERQMMILRAVVRDFTNSGVPVGSKALAKQLPIHVSSATIRNEMAALEDQGLIRKTHSSSGRIPSVEGYRYYVDHLVKPDPLRPNDLNMIQSSLGGDFHKIDEIISQSATILSNLTSYTAFTLKPELKDSRLSGFRLVPLGHRQVMAILVTDSGDVENQTFDVTEAVTGEQLEAVVRLINDQLVGLTLPEVLQKLRTDIPAKITHYLQSPQGFLDIFGDVLTRAAQERFYVGGRLNLLNFSQDSDVDSLKALYSLIDKTDDIANVLGQPRDNISVQIGNEMTNDALRNYSLITATYDVNQHGRGMIAILGPTRMPYSRMLGLVGAFREELAKKLLDYYRYYDE
>NZ_LT854705.1|WP_087741916.1|1225191_1225461_+|hypothetical-protein
MLGYVLGRDGDIHDFIETLKRVHGSLDDSEIQLVRELVELATHPGYTINMAEKLSLTSVELSDYLQHLRACGLIDYWEKAAKPLSLLSE
>NZ_LT854705.1|WP_087741917.1|1225496_1225703_-|hypothetical-protein
MDNLIQPVLTKVRQISTRWTRTYSLEGIEDDQAKDFAKQLAQADTENLATYKVRGHAPRSLTLEIHRH
>NZ_LT854705.1|WP_087741918.1|1225745_1226111_-|hypothetical-protein
MREEKVTFTKTDWQRAQTAVFNEYDRLIKQLHLAGVDAAIAQARRIVIYQDLLEEWKHAVPTLMTDLSDNPVALAVFDDMDADGQSHILDRCAKKMEAWPDYIPSPLTIWLELEEDANREG
>NZ_LT854705.1|WP_057730767.1|1226243_1226621_-|large-conductance-mechanosensitive-channel-protein-MscL
MLKEFKEFIARGNVMDLAVGVIVGAAFTAIVNSLVKNLINPLLGIFVGSIDFSNLVFTVGDAHFRYGAFINSVINFLIIAFVVFLLVKFLNHLLPAPKDDEAADEPSAEEKYLKEIVDLLKKDEH
>NZ_LT854705.1|WP_087741919.1|1226850_1227117_+|hypothetical-protein
MAVDKWPIDPELIDDDLENILDFEARLLCIIGSPLTDQEIAEAATIPVAIITAIRQQEVDYHDMKMTDALALDEVYELAQEAYDEPTH
>NZ_LT854705.1|WP_087741920.1|1227490_1227808_+|hypothetical-protein
MLSRTKEYLRQHNYRYEKSYIRPLMAPESVYVFKFGRHSLNNRVIIRYGHTWTGRQRINEIDLRLHKQKHPRVFQNEADMLDYLETHLARREQKQADHPTDTEKV
>NZ_LT854705.1|WP_087741921.1|1227900_1228851_+|50S-ribosomal-protein-L11-methyltransferase
MQWTEVSVITTNEAVEAVGNILQEAGASGVKIDDAADYEHLKPGKYGEIVDLKTIPHRTSGAEITAYYPETVFIPEILPTIKQRVSGLSQFGLDPSPATVTSQAVADESWATAWQKYYHPVRVTRYLTVTPSWENYQPVQADEHVIRLDPGMAFGTGTHPTTVLSLTELEMVVRGGESMYDVGTGSGVLSIAAKYLGVDQIKAFDLDDVAVRSAKTNLDLNPIAQDVVAAPNDLLNGIHQPVDLVVANILAEIIVPLVPQAWENLQSGGHFLTSGIIADKLDTVVAAQEKQGFIIDNVLQMKDWRGVIAHKPMEDE
>NZ_LT854705.1|WP_087741922.1|1228854_1229595_+|16S-rRNA-(uracil(1498)-N(3))-methyltransferase
MQRYFLDVTGQDGQTVTLPETVTHHWVTVLRAQVGDTAEFVDHTAHLFHGQLLAVTDRQATVQLTAVATPAVELPVHTVIACGLPKQEKAEWITQKATEMGVDQIIFYAGDWSVAKWQGNKVAKKLARLTKVANGAAEQSHRLVRPTVSYLPNLAAVLKTPNDCPLLAYEESAKQGEHSALTQRLTAMTPGQTVLAIFGPEGGISPAEVQTAQAAGATLVGLGPRILRTETAPLYFLAAASTLWEL
>NZ_LT854705.1|WP_087741923.1|1229674_1230022_+|hypothetical-protein
MAFLEKMGWRYWLTGLIMGIVLPALATLLNISTVMRFGGLLLVINGGVAIAVGRLVALKARPMWLLLVLPALYLLGAYGFLPAYTRYFALVYLCVSYLAYGLTATTQTTQSESKN
>NZ_LT854705.1|WP_087741924.1|1230039_1232268_+|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase
MTKERVWTAEEVIARVGKYMNAQHVEMVVKACHFATVAHRDQTRQSGEPYIMHPIQVAGILADLNMDPETVSAGFLHDIVEDTGVTLSDVRELFGDDVALIVDGVTKLGKIKYKSNKEQLAENHRKLLLAMSKDIRVMIVKLADRLHNMRTLQHLRPDKQRRIANETLEIYAPLADRLGISTIKWELEDISLRYLNPQQYYRIVHLMNSRRDQREQYIAAAIKVIQSSIKDLHLHPEIYGRPKHIYSVYRKMKDQHKQFSQIYDLLAIRVIVDTIKDCYAVLGAIHSQWKPMPGRFKDYIAMPKANMYQSLHTTVIGPEGKPLEVQIRTKEMHAVAEYGVAAHWAYKEGVKDKVQATNTGEKLNLFKHIIELQEDTDDAADFMDSVKGELFGDHVYAFTPKGDVLELPKGAGPLDMAYAIHTEVGHHTTGATINGKIVPLNYEIKNGDIVDIRTSSSSAGPSRDWLKLVSTRRARNKIKQFFRLRDREQNITQGQEMVERLIRDAGYDPKAIMTKENVDKVTAKLHYQHVDDLLAAIGFGDLQPQGVVNRLTDDVRQAAEDKRCRQEEREILEEHQSIKNDSDTDKKDRKKQPDGVVIEGVDNLLVRLSHCCAPVPGDQITGYITKGRGVSVHRVDCPNVRHAEESGERIVPVRWGDEHGDRTNYHADIEVQGYNRNGLLNDVLRTINNSTKDLTSINGKVDHNKMVIISVSLGIRNRWELQRIVDNIKNIPDVYVVKRPFR

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Crispr_ID: NZ_LT854705_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT854705_7

2202770-2202869

Orphan

Consensus_repeat	Method
GTCATGTGACTGCTGGATGAACTGTCGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LT854705_7

>merge|NZ_LT854705|7|2202770-2202869|CRISPRCasFinder
GTCATGTGACTGCTGGATGAACTGTCGATTTCGTTGGAGCTATCTTCATCGACACCGCCGCCAGCGCCGTCAGTCATGTGACTGCTGGATGAACTGTCGA

>NZ_LT854705|7|7|2202770-2202869|CRISPRCasFinder
GTCATGTGACTGCTGGATGAACTGTCGA	TTTCGTTGGAGCTATCTTCATCGACACCGCCGCCAGCGCCGTCA
GTCATGTGACTGCTGGATGAACTGTCGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT854705.1\|WP_087742462.1\|2211179_2214491_-\|YhgE/Pip-domain-containing-protein	unknown	unknown	gnl\|CDD\|274414
NZ_LT854705.1\|WP_087742454.1\|2195264_2196614_+\|NCS2-family-permease	unknown	unknown	gnl\|CDD\|225161
NZ_LT854705.1\|WP_057733561.1\|2203848_2204955_-\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NZ_LT854705.1\|WP_057733554.1\|2209772_2210117_-\|AzlD-domain-containing-protein	unknown	unknown	gnl\|CDD\|377512
NZ_LT854705.1\|WP_087742453.1\|2194078_2195095_-\|adenosine-deaminase	unknown	unknown	gnl\|CDD\|238645
NZ_LT854705.1\|WP_057733556.1\|2208005_2209199_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|225139
NZ_LT854705.1\|WP_087742458.1\|2200754_2200973_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_087742456.1\|2198485_2198797_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_087742459.1\|2205197_2206382_-\|ROK-family-protein	unknown	unknown	gnl\|CDD\|224851
NZ_LT854705.1\|WP_087742455.1\|2196623_2198393_+\|adenine-deaminase	unknown	unknown	gnl\|CDD\|223933
NZ_LT854705.1\|WP_057733599.1\|2216310_2217486_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|227335
NZ_LT854705.1\|WP_087742452.1\|2192533_2193913_+\|DHA2-family-efflux-MFS-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|129794
NZ_LT854705.1\|WP_045808046.1\|2200455_2200707_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_057733546.1\|2217496_2218186_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_LT854705.1\|WP_087742461.1\|2210135_2210939_-\|AzlC-family-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224215
NZ_LT854705.1\|WP_087742460.1\|2206882_2207809_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|115579
NZ_LT854705.1\|WP_057733565.1\|2201235_2201928_-\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|172606
NZ_LT854705.1\|WP_172825284.1\|2214931_2216239_-\|serine-hydrolase	unknown	unknown	gnl\|CDD\|224600
NZ_LT854705.1\|WP_087742451.1\|2190959_2192306_-\|APC-family-permease	unknown	unknown	gnl\|CDD\|183096
NZ_LT854705.1\|WP_087741887.1\|2198880_2199897_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382

Protein	Function_ID	Function_description	E-value
NZ_LT854705.1\|WP_087742462.1\|2211179_2214491_-\|YhgE/Pip-domain-containing-protein	gnl\|CDD\|274414	TIGR03062, hypothetical_protein_lp_1332, YhgE/Pip C-terminal domain. This family contains the C-terminal domain of a family of multiple membrane-spanning proteins of Gram-positive bacteria. One member was shown to be a host protein essential for phage infection, so many members of this family are called "phage infection protein". A separate model, TIGR03061, represents the conserved N-terminal domain. The domains are separated by regions highly variable in both length and sequence, often containing extended heptad repeats as described in model TIGR03057.	8.3452e-78
NZ_LT854705.1\|WP_087742454.1\|2195264_2196614_+\|NCS2-family-permease	gnl\|CDD\|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	6.10005e-148
NZ_LT854705.1\|WP_057733561.1\|2203848_2204955_-\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	2.49754e-41
NZ_LT854705.1\|WP_057733554.1\|2209772_2210117_-\|AzlD-domain-containing-protein	gnl\|CDD\|377512	pfam05437, AzlD, Branched-chain amino acid transport protein (AzlD). This family consists of a number of bacterial and archaeal branched-chain amino acid transport proteins. AzlD is known to be involved in conferring resistance to 4-azaleucine although its exact role is uncertain.	1.38148e-17
NZ_LT854705.1\|WP_087742453.1\|2194078_2195095_-\|adenosine-deaminase	gnl\|CDD\|238645	cd01320, ADA, Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in the purine pathway. Low, as well as high levels of ADA activity have been linked to several diseases.	7.95142e-135
NZ_LT854705.1\|WP_057733556.1\|2208005_2209199_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|225139	COG2230, Cfa, Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane].	8.04171e-112
NZ_LT854705.1\|WP_172825284.1\|2214931_2216239_-\|serine-hydrolase	gnl\|CDD\|224600	COG1686, DacC, D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane].	3.13771e-83
NZ_LT854705.1\|WP_087742459.1\|2205197_2206382_-\|ROK-family-protein	gnl\|CDD\|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	4.61816e-33
NZ_LT854705.1\|WP_087742455.1\|2196623_2198393_+\|adenine-deaminase	gnl\|CDD\|223933	COG1001, AdeC, Adenine deaminase [Nucleotide transport and metabolism].	0
NZ_LT854705.1\|WP_057733599.1\|2216310_2217486_-\|sensor-histidine-kinase	gnl\|CDD\|227335	COG5002, VicK, Signal transduction histidine kinase [Signal transduction mechanisms].	5.5099e-49
NZ_LT854705.1\|WP_087742452.1\|2192533_2193913_+\|DHA2-family-efflux-MFS-transporter-permease-subunit	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	5.76619e-73
NZ_LT854705.1\|WP_057733546.1\|2217496_2218186_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.24876e-88
NZ_LT854705.1\|WP_087742461.1\|2210135_2210939_-\|AzlC-family-ABC-transporter-permease	gnl\|CDD\|224215	COG1296, AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism].	1.65544e-33
NZ_LT854705.1\|WP_087742460.1\|2206882_2207809_-\|hypothetical-protein	gnl\|CDD\|115579	pfam06933, SSP160, Special lobe-specific silk protein SSP160. This family consists of several special lobe-specific silk protein SSP160 sequences which appear to be specific to Chironomus (Midge) species.	0.00269558
NZ_LT854705.1\|WP_057733565.1\|2201235_2201928_-\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	gnl\|CDD\|172606	PRK14116, gpmA, 2,3-diphosphoglycerate-dependent phosphoglycerate mutase.	1.52082e-168
NZ_LT854705.1\|WP_087742451.1\|2190959_2192306_-\|APC-family-permease	gnl\|CDD\|183096	PRK11357, frlA, amino acid permease.	2.64853e-52
NZ_LT854705.1\|WP_087741887.1\|2198880_2199897_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	8.09877e-67

>NZ_LT854705.1|WP_057733565.1|2201235_2201928_-|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase
MAKLVLIRHGQSEWNLSNQFTGWVDVDLSEKGVEEAKAAGKKVKEAGLEFDYAYTSVLKRAIKTLHYVLEESDQLWVPETKTWRLNERHYGALQGLNKKETAEKYGDDQVHIWRRSYDVLPPLLSADDEGSAVNDRRYADLDPNIIPGGENLKVTLERVMPFWEDQIAPKLLDGKNVIIAAHGNSLRALSKYIERISDDDIMDLEMATGEPVVYDFDDKLNMTNKVKLGK
>NZ_LT854705.1|WP_087742458.1|2200754_2200973_-|hypothetical-protein
MYDVDELLEAKRQIDSTLHKIREVVKTFEAKENPSRYKSQLTLAKRRLKAFGIANQLIEDKLAELENDHGKR
>NZ_LT854705.1|WP_045808046.1|2200455_2200707_-|hypothetical-protein
MATKEVTQVEMMKIIALFRKEGFKGEYEDFQRVSGTDREFFVVMSNEQGIKALFRASLMLNAVQFQYVLDDKHTFVQEDADAS
>NZ_LT854705.1|WP_087741887.1|2198880_2199897_+|IS30-family-transposase
MTHSQINTHKHYQQLSLSDRATIQALRATGDTATVIAQKLHRSKATISREITRGSVTQLDSKRHSHQVYLAETAQAIHDRKRDRTGHHAFLKTGRAFFKALTKELTRKPRVHSVDSFVHFYRDQGKSCPSTTTVYRYIDAGLLELDNMTLPKKLRRRVKGYKNAHKRKNKKIYGDSIELRPAAVNDRTGVGHWEGDLVKGIRSADEPALMTLTERYSRTEIIVKIPDYHADTCLKALQDTINDYGAKEFESITFDNGSEFAKLSEIVGTQIYFAHPYSPWERGTNENTNGLLREYFPKGKSLRDVTLVEVQAVQSALNHRPRRILNYLRPCDYYRRMA
>NZ_LT854705.1|WP_087742456.1|2198485_2198797_-|hypothetical-protein
MNCKLGHFYYGKSWKESIPIANQIDLQKILLVATATFETTDVADAILRNGFDVTALLRINFVGILDLGFKSLQVLRSTVVKSKKIDKLDKDLQDEWDRVYQTI
>NZ_LT854705.1|WP_087742455.1|2196623_2198393_+|adenine-deaminase
MTTLNQYLDAGAAKLPADLVIEHGTLANVDTGEFYPADVAVYQQRIVAVDDDVSAYVGPQTRHIDATGKTLVPGLIDGHIHVECSKLSMTRFAQLAVPHGTTSIVSGLDEYISVIGVQGLDEIFAEIKNLPLKVFWGLPYKTPYTIPKSTIAYNVTAADHEHYLPQENCYGVWETVKEAVATQDPDTLKALELAKRYHKPIFGCSPMTQGRDLNAFLMSGVHIDHESYSHQEFLEKARKGLRVVIRESSVTKFLAENIRALTEGPAGVARHISFCTDDVNARDVLAHGHLDHMVRLAIQAGVAPMTAIQMASLNGAEAYHVDDTVGSIAPGKDADILLVDHPGTFNVETVISRGQLVTENGQPVLAFTPPKRSAALQGQLKHTLLTPAEFDYPVAATTGTARVRTIHSVGPFVRKAKDVTLQIRDGRVQPDAAQDVAAVSVIERHGVNQNHARGFISGWSITHGAIATSAAPDDNNLVVAGINSADMALATNTLIDCGGGQVVVDHGQVVALLKLPIAGITTDLTPKDLAAKEIELKRAAEQLGSTLPDPLFYLSFLPITAIPDLAITDGGNVDYTQLTYFDPILKISE
>NZ_LT854705.1|WP_087742454.1|2195264_2196614_+|NCS2-family-permease
MLKANRATVTTGFLERTFHLSEQHTTVRQELLAGLTTFVSMAYILFVNPSILGAAGMDKGAVFTVTALSAILGCLLMAFLANYPIAIAPGLGDNAFFTYSVVLGMGIPWEKAMAGVFVAAILFTLLSFLKVREVVIDAIPSDLKLAMAAGIGIFIAFVGLQGGGLIVASKTSLVEIGSFTVPTTWLTIFGIFVIAILMAMRVPGSIFIGLVASTILGLVTGLIKAPSSLISMAPSMGPTFGVSLKNLPSVADPQMWAVVLIFLLVAFFDTAGTLIGLAQQAGIMKDNKMPRIGRALMSDSLSMLAGSVMGTTPTAAYVESSAGIAVGGRTGLTALTTGILFVFSLMFSPLLTVVTSQVTAPALIIVGVLMASALKNIHWDQFEVAVPAFLTIVGMPLTYNISYGIAFGFLTYPILMTAAGRRKEVNAVMWSLLVVFIVLLYILNILPKS
>NZ_LT854705.1|WP_087742453.1|2194078_2195095_-|adenosine-deaminase
MSTEVTQAFTHGLPKAELHLHIEGTLEPDLKLKLAQRNHVDIGQHTIEEVQKAYQYDDLASFLAVYYPAMNVLQHEQDFYDLAFAYLQRAAANNVRHVEIFFDPQAHTSRGIPFKTVIDGLYRATVDARALNVDAQLILCFLRDFSKESARQTLETALPYKDKFIGIGLDSDEHNNPPMKFARQYEDAAAAGLHLTAHCDIDQKDSIEHIRQALEQLDVERLDHGTNIVEDPDLVQLVARKGIGLTSCPLSNSFVSPEMKGKEVLDLLAQHVKVSINSDDPAYFGGYIGDNYYALADKFNLTKAQVVQLARNSFETSWISATQKALYLKELDAYVATH
>NZ_LT854705.1|WP_087742452.1|2192533_2193913_+|DHA2-family-efflux-MFS-transporter-permease-subunit
MTNKRISRSLIVMVFGTFFGILCSTLMNVGLPQLMKAFQISEAQVQWVTNGYMLVNALMIPVSAYLIKRFLFRYLYITATVIFLLGTLLGALCDQFILVIVARMIQAVGAGMMMPLVNVLAIRYAKPEKKGSIMGIIGLAFNFSPIIGPTVSGIILDYLSWRWLFIVILPFIVITLIASLIILPKIPHNEAPHFDLRGLIIISIGLWAVLMGLSNISTASFLSWQVGGLVLIGLVFMAGFYRSQLHRQDPLINLHVFNHQQFVVATVINMLIIATMYGNTILLPLLVQTIQHRSALVSGLVILPGALLTGTLSRLSGRLYDRISVKKLVFAGLTIDCAGTLMQAFVGTESSAWVLAIFQAVRQLGLVTMLIPLQTHALGLLPYDMVPDGVATFNTIRQVAASFGTAIIIAVVAVVNSRVAGDGRYGIEAGFLVCFILLVASLVVARRLHRQPDLLKHVG
>NZ_LT854705.1|WP_087742451.1|2190959_2192306_-|APC-family-permease
MKETSTVGLNRSLGLWSALSLVIGTVIGSGIFFKQASVLQMTGSTNLALLAWLLGGVITLADGLTLSEIGSQIPHTGGLYQYMTHIYGEFWGFMSGWMQVIVYAPSIVGSIAGYLGLLMVNFFGISSFWKAPIAIITIVLVAVLNMLENRYGATFAIVTTICKLVPILVIIVFGLFFGNQSALGETITSVHQSMGNFGVAVLGTIFAYDGWILITNLGGEIKHPEKLLPLAIILGITIIIVLYLGVTYGIFRSMSAARIDALGENATAYFATSAFGTWGGRLINIGIMISIIGALNGKVMSFPRIYYAMAAKHQLPFAKYLGRLNPKTHTPVVATLTLLVLTAAMILTIDTDRLSELCIFVMYSFYIAAFVGVFILRRRHGGRPTGFRTPGYPIVPIFAILGTGFVVISELFSDFTGAAASMIVIALGMPLYYYLKRKYRDTHDPDVI
>NZ_LT854705.1|WP_057733561.1|2203848_2204955_-|AI-2E-family-transporter
MNLWERFTTNIRLRRFVVLAFIILILWLVRSEMNTILLTFIFTFLVLQLVKFVRRHVKIPTQLIVVLTYVIILGGLYWAVTTYLPQIVTSSVHGIEKLYKFYQNPDNDTNQIARWVTNYISTSDLLGQVQNGAKVVLNYVSTIGSFGLTVFMSMILSFFFTIESKQMTAFSQRFLTSTYGWVFQDIKFFADKFINTFGVVLEAQFFIAMCNTVITTAILAIMKMPQLPTLAIMIFILSLVPVAGVIVSVIPLAVLGYSVGGYRYIVYILVMIVVVHALEAYVLNPKFMSSRTELPIFYTFVVLLAGEQLFGVWGLIVGVPIFTFFLDILGVRPVHGLHPGVDVEKLRQYRQTHGKRRHHHDDDQDHSE
>NZ_LT854705.1|WP_087742459.1|2205197_2206382_-|ROK-family-protein
MIINKHIMRTTNEKQVLQQIVNAGPISRSQISRNLSLNKVTVSDIYSELLHEGLIREVGHGVSTRNGGRKPVMALLNVDYGYVISINLLRQRFTMLACRLDGKSEDYTSVSTRNVDLTSVLDMIEEHIRQMMGDRDTRLLGLSFGLDGVIYENQILNAGLNGLKDFDLAKYFGDKFNVPVVLENLANEAAIFERDFSGEGVYENLISVTIRDQVSAGIITNGHLYRGHRGEAGVIGKCPLADRYQEQNHETVNHYVSETSVLKRIMAYQKLDRVDVNRIRRDYLGHQPELLAILDEFSYYLAKVLANISSSFAPDAILLNVPILELLPELMDDVRGYVDKLAIPRKAPLLLTKNAKEASLMGGASAIIHRVLALDDLQLTFRNERPVVLEQIES
>NZ_LT854705.1|WP_087742460.1|2206882_2207809_-|hypothetical-protein
MKKWVWVVATIVVALLIGGYAYSNHHATAKEYQAAMTNGRTALKNKDYTQAESYFQNALKRRLNDRTAQTYLTQTQRFVSGENAMDARKFGHAQARYQTVKTTKNGSTVLVNRATKRLKQVKVIRANVAQFKQLLSKAQDQNQALNYGTSNTTLDELFNNSKFQQVYYKNLYAQALALRKANNAGQTSVVTNSSSAATSTTGSGTTTSSSSATTGTTSNSSSNGASLTSSESAAAQNYQGSNEYTVTKKQKELNGKVITAGQISSARQTINAAGGQADAMSDQDVRVALQQANKKGLSLTKYTQQYLK
>NZ_LT854705.1|WP_057733556.1|2208005_2209199_+|class-I-SAM-dependent-methyltransferase
MLEKTFYKTFLSHTFNIPVRVNYWDGTSDVYGTGTPANTITIHQAIPVKEISRNASIALGEAIMDGTIEIDGSIEDLLTAAYENADSFFHNKKYIHFLPKQKHTEKESKADVQNHYDIGNNFYQLWLDSTMTYSCAYFETPDDDLETAQVNKVHHIIKKLNPQPGKTLLDIGCGWGTLMLTAAKEYGLHVTGITLSQEQYDYVTQRINDEGLQDVAEVRLEDYRELGNEQWDYITSVGMFEHVGAENLGEYFNCVQKYLMNDGVALIHGITRQQGGANNGWLNKWIFPGGYVPGLVENTTHIIENGLQIDDMEPLRRHYQKTVEIWDQNFNQHREEVAKMFDDKFVRMWDLYLQACAASFKSGNIDVIQYLISKGPSARMLPMTRDYMYAETDKVTD
>NZ_LT854705.1|WP_057733554.1|2209772_2210117_-|AzlD-domain-containing-protein
MSTVNTWTSTQHFWLIILGFFVAFLPRFIPLMLFTKREIPEWFNEWMKFVPVSLFTALVVKDVFIDSKSYQLMFTQVPEMLAAVIVIIIAYRTRSMALSVITGLIGVFLLSMVI
>NZ_LT854705.1|WP_087742461.1|2210135_2210939_-|AzlC-family-ABC-transporter-permease
MNKRRPNPKRVPDPNEPLWRSTLRVAMPLNLSYIPIGLACGILLHAAGFNTLLTGLVSLLIFSGGAQFLIATMLTINSPLLSIVLMLFFLELRYALLSSSLSPYLKGQSNRFLFIFAISLNDENYAINYLKFATDKKWTGKEALMVEHYSLLFWAMSNVIGSLIGSALKIDLGIVNFALTALFLYMIVMQIKNRLTVVICLISGVLAAVCMMITKSTLGLVISTIISSLIGFGLETTLRKRLPDSHWLWKLRGPGAKQSAVESSDGK
>NZ_LT854705.1|WP_087742462.1|2211179_2214491_-|YhgE/Pip-domain-containing-protein
MKMVKGEWSYIRHNRLILISVLAIMFIPFLYSIFFLRSVWDPYGETSELPVAVVNLDKPVTYQGQKLNVGDQTVTNLKKNHQLGWKFVSKQQAAQGLKDRKYYTVITIPKNFSAHAATALDEHPKKMTLTYNTNASANYIAEVMSQVGATKLQNEISAKVTKAYAQATFKLVYQVGKGMDKAATGSAQLKDGTTTLTDGLNTYTTGVKKLDNGLQQMKTSVKPLATGIQQLNDGAATLKSGLTQYTSGVSQYTAGVGQYTSGVGQYSAGVNQYTSGVGQYSAGVNQYTAGVGQYTSGVNQFTSGVSQLSAGMPKLTAGTKQLSTGASSLNSGVYKYVDGVYTLNDGVQKLGAGVGPLKSGVSQLSSGSSALNSGLSKLSDNSSSLNDGASSLASKATELSSSVSQLGTAANMATNQLNQLDLSSLSGLPSQVKALSAGLTQVSQGVDGISKYASDIQQRAKSGSTATPATSAAKTVTKTTTSGADSSSVTAAKDATSAAAATAASLKAAAAKEDNSEEVSALASKLASETAAANDKTGAISTSGTSTTEETKTTGSDSSSSSSSSSDANMTAIANDAAAIANASVQVTGGLGVINKQLATAISSLPDTGNLASQVAELKQFAGAVSQLNAAVNPSSGTSLSQGVDTLTNGVKTYTSGVDSAFNGSTTLNNGLNSLNLQVPTLSDGITQIMNGTAELAKNGKALKSGSSQVSSGAATLNSGLQTAAAGVNKLNANTGKLTAAGNKLNSSTGQLTAAGNKLNSSTGKLTAAGNKLNSSTGQLTAAGNKLNQASPQLTSGASQLAAGTAQLNSKVPTLTSGVNQLADGSAQLNENSPKLVAGAKKLNAGNGKLAKSLKSGADQINDQPLTNKTADMFSSPTKLAHKNYSYVPNYGHALAPYVLSVALYVGALVFNFAFPIRKVSLEGGSATGWFFSKVSIGAVEALAMAVIEPSLMMLGGLTVEHPGQLIILSIVFSEASMFIVMFLSMLLDNPGRFIAMVLLMLQLGGSGGTFPMEVTNHFYNVVHPFLPMTYSILGFRQAITDGMGSGVEWQAVMVLALFTVISLALLFPTMHWLQKKHLMGVSQLDDNQKLQAVEDPTSRRHS
>NZ_LT854705.1|WP_172825284.1|2214931_2216239_-|serine-hydrolase
MVGVVAAVTLLTGGLSTGAVTPTVTAHAATSTTSSTVNLKAKAGIAVDATTGQILYEKNGDQSLPVASMSKLLSIYLVLQAVHAGKLKWDQKITISKPIAKVAENTDLSNVPLRAGHSYTVKALYQASLIYSANGAIEALGSAVAGSPHAFVTQMKAQAKKLGMTNVKIYNACGLTNKQVGDLGYSNVAGKAENEWSAADQAKLAVALLDKYPEVLQTTKITKMWFEKGTKDATKMENWNWMLKGLTASYTKLHVDGLKTGTSDAAGANFTGTAHNNGNRIITVVLHAAHKSETDPSRFQQTQKMMSYVYNNFKTVTYHAGQSITGAKSVTTHDAKTKTAKTALASDVKLWIRNDQVASNITAKPQLKASLTKDNALEAPVAKNQQIGTANLSLKGDQLGFLGNTKTVKVPLKVTQSVEKANVFVRMWRWVVALF
>NZ_LT854705.1|WP_057733599.1|2216310_2217486_-|sensor-histidine-kinase
MKLTTREKSALFMEGVVTVILLLMLNLALLVLIVQAIESNPGLRDGIFIIKRSVVLGPHHYQLWSWENLFIGLMMVGDALVVWWRLIRRYKQMQLHHIIEELHYIANGHFDHRIPFRVSGDVQRVVDSVNALVDSVIHSMDEERAIEKSKDELITNVSHDIRTPLTSIIGYLGLIEDKQYHSETDLLKYTHTAFLKSKQMKSLVDDLFEYTKVRQTDTPLSLTKIDLGAMLEQLAASFELEAQKKGMDIGADVGDTPLMMEADPEKLVRIFNNLVSNALKYGDGGKHINLVAKRVSADELEVRVTNDGPKIPKKSLALIFERFYRVEESRSKETGGTGLGLAIAQSIVALHGGYIYVESDDALTSFVIHLPTVHAHPLAVPQRLKAAGTAN
>NZ_LT854705.1|WP_057733546.1|2217496_2218186_-|response-regulator-transcription-factor
MKILVVDDDKEIAQLLEIYIKNEGYEPLTAYNGKEALTKLHTTPDIALMILDVMMPEMSGIEVIKEVRKDSQIPILILSAKTGDMDKIQGLITGADDYVTKPFNPLEVMARVKSLLRRSQDQVTDDSPDVLDIGTLTINKDSHEVKTIAGKTVSLTALEFGILYLLASHPNRVFSADEIFERVWRQESIVSAKTVMVHVSHLRDKIEEATNGEKVIQTVWGVGYKIESH

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Crispr_ID: NZ_LT854705_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT854705_8

2209366-2209574

Orphan

I-E,II-B

Consensus_repeat	Method
CACCCCCACACGTGTGGGGAATAC	CRISPRCasFinder
CACCCCCACACGTGTGGGGAATACA	CRT

3 spacers

The CRISPR arrays of NZ_LT854705_8

>merge|NZ_LT854705|8|2209366-2209574|CRISPRCasFinder,CRT
ACCCTCCACACGTGTAGGAAATATAAGCCATGTACAACAAACATAGACCAATGATAAGGGTCCACCCCCACACGTGTGGGGAATACTCTGGTTGAAAATAAAACGTCAAGTAGGTACAAGAATCACCCCCACACGTGTGGGGAATACATTCGTTTTCATTGCCACTTGCTTAGACACACGGAATCACCCCCACACGTGTGGGGAATACA

>NZ_LT854705|8|8|2209366-2209573|CRISPRCasFinder
ACCCTCCACACGTGTAGGAAATAT	AAGCCATGTACAACAAACATAGACCAATGATAAGGGTC
CACCCCCACACGTGTGGGGAATAC	TCTGGTTGAAAATAAAACGTCAAGTAGGTACAAGAAT
CACCCCCACACGTGTGGGGAATAC	ATTCGTTTTCATTGCCACTTGCTTAGACACACGGAAT
CACCCCCACACGTGTGGGGAATAC

>NZ_LT854705|8|5|2209366-2209574|CRT
ACCCTCCACACGTGTAGGAAATATA	AGCCATGTACAACAAACATAGACCAATGATAAGGGTC
CACCCCCACACGTGTGGGGAATACT	CTGGTTGAAAATAAAACGTCAAGTAGGTACAAGAAT
CACCCCCACACGTGTGGGGAATACA	TTCGTTTTCATTGCCACTTGCTTAGACACACGGAAT
CACCCCCACACGTGTGGGGAATACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT854705.1\|WP_057733546.1\|2217496_2218186_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_LT854705.1\|WP_057733561.1\|2203848_2204955_-\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NZ_LT854705.1\|WP_057733554.1\|2209772_2210117_-\|AzlD-domain-containing-protein	unknown	unknown	gnl\|CDD\|377512
NZ_LT854705.1\|WP_057733556.1\|2208005_2209199_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|225139
NZ_LT854705.1\|WP_087742458.1\|2200754_2200973_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_087742456.1\|2198485_2198797_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_087742459.1\|2205197_2206382_-\|ROK-family-protein	unknown	unknown	gnl\|CDD\|224851
NZ_LT854705.1\|WP_087742464.1\|2218880_2219447_+\|matrixin-family-metalloprotease	unknown	unknown	gnl\|CDD\|239796
NZ_LT854705.1\|WP_057733599.1\|2216310_2217486_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|227335
NZ_LT854705.1\|WP_057733542.1\|2219601_2220741_-\|IMP-dehydrogenase	unknown	unknown	gnl\|CDD\|235507
NZ_LT854705.1\|WP_087742462.1\|2211179_2214491_-\|YhgE/Pip-domain-containing-protein	unknown	unknown	gnl\|CDD\|274414
NZ_LT854705.1\|WP_087742465.1\|2221002_2222712_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227904
NZ_LT854705.1\|WP_157667882.1\|2202093_2203656_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|223039
NZ_LT854705.1\|WP_087742466.1\|2222749_2224402_-\|glycosyltransferase-family-39-protein	unknown	unknown	gnl\|CDD\|379080
NZ_LT854705.1\|WP_087742461.1\|2210135_2210939_-\|AzlC-family-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224215
NZ_LT854705.1\|WP_087742460.1\|2206882_2207809_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|115579
NZ_LT854705.1\|WP_057733565.1\|2201235_2201928_-\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|172606
NZ_LT854705.1\|WP_172825284.1\|2214931_2216239_-\|serine-hydrolase	unknown	unknown	gnl\|CDD\|224600
NZ_LT854705.1\|WP_045808046.1\|2200455_2200707_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_087741887.1\|2198880_2199897_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382

Protein	Function_ID	Function_description	E-value
NZ_LT854705.1\|WP_087742462.1\|2211179_2214491_-\|YhgE/Pip-domain-containing-protein	gnl\|CDD\|274414	TIGR03062, hypothetical_protein_lp_1332, YhgE/Pip C-terminal domain. This family contains the C-terminal domain of a family of multiple membrane-spanning proteins of Gram-positive bacteria. One member was shown to be a host protein essential for phage infection, so many members of this family are called "phage infection protein". A separate model, TIGR03061, represents the conserved N-terminal domain. The domains are separated by regions highly variable in both length and sequence, often containing extended heptad repeats as described in model TIGR03057.	8.3452e-78
NZ_LT854705.1\|WP_057733554.1\|2209772_2210117_-\|AzlD-domain-containing-protein	gnl\|CDD\|377512	pfam05437, AzlD, Branched-chain amino acid transport protein (AzlD). This family consists of a number of bacterial and archaeal branched-chain amino acid transport proteins. AzlD is known to be involved in conferring resistance to 4-azaleucine although its exact role is uncertain.	1.38148e-17
NZ_LT854705.1\|WP_057733556.1\|2208005_2209199_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|225139	COG2230, Cfa, Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane].	8.04171e-112
NZ_LT854705.1\|WP_157667882.1\|2202093_2203656_-\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|223039	PHA03307, PHA03307, transcriptional regulator ICP4; Provisional.	2.28054e-11
NZ_LT854705.1\|WP_172825284.1\|2214931_2216239_-\|serine-hydrolase	gnl\|CDD\|224600	COG1686, DacC, D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane].	3.13771e-83
NZ_LT854705.1\|WP_087742459.1\|2205197_2206382_-\|ROK-family-protein	gnl\|CDD\|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	4.61816e-33
NZ_LT854705.1\|WP_087742464.1\|2218880_2219447_+\|matrixin-family-metalloprotease	gnl\|CDD\|239796	cd04268, ZnMc_MMP_like, Zinc-dependent metalloprotease, MMP_like subfamily. This group contains matrix metalloproteinases (MMPs), serralysins, and the astacin_like family of proteases.	2.09175e-13
NZ_LT854705.1\|WP_057733599.1\|2216310_2217486_-\|sensor-histidine-kinase	gnl\|CDD\|227335	COG5002, VicK, Signal transduction histidine kinase [Signal transduction mechanisms].	5.5099e-49
NZ_LT854705.1\|WP_057733542.1\|2219601_2220741_-\|IMP-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
NZ_LT854705.1\|WP_057733561.1\|2203848_2204955_-\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	2.49754e-41
NZ_LT854705.1\|WP_087742465.1\|2221002_2222712_-\|hypothetical-protein	gnl\|CDD\|227904	COG5617, COG5617, Predicted integral membrane protein [Function unknown].	0.000593781
NZ_LT854705.1\|WP_057733546.1\|2217496_2218186_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.24876e-88
NZ_LT854705.1\|WP_087742466.1\|2222749_2224402_-\|glycosyltransferase-family-39-protein	gnl\|CDD\|379080	pfam13231, PMT_2, Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.	0.000328654
NZ_LT854705.1\|WP_087742461.1\|2210135_2210939_-\|AzlC-family-ABC-transporter-permease	gnl\|CDD\|224215	COG1296, AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism].	1.65544e-33
NZ_LT854705.1\|WP_087742460.1\|2206882_2207809_-\|hypothetical-protein	gnl\|CDD\|115579	pfam06933, SSP160, Special lobe-specific silk protein SSP160. This family consists of several special lobe-specific silk protein SSP160 sequences which appear to be specific to Chironomus (Midge) species.	0.00269558
NZ_LT854705.1\|WP_057733565.1\|2201235_2201928_-\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	gnl\|CDD\|172606	PRK14116, gpmA, 2,3-diphosphoglycerate-dependent phosphoglycerate mutase.	1.52082e-168
NZ_LT854705.1\|WP_087741887.1\|2198880_2199897_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	8.09877e-67

>NZ_LT854705.1|WP_057733556.1|2208005_2209199_+|class-I-SAM-dependent-methyltransferase
MLEKTFYKTFLSHTFNIPVRVNYWDGTSDVYGTGTPANTITIHQAIPVKEISRNASIALGEAIMDGTIEIDGSIEDLLTAAYENADSFFHNKKYIHFLPKQKHTEKESKADVQNHYDIGNNFYQLWLDSTMTYSCAYFETPDDDLETAQVNKVHHIIKKLNPQPGKTLLDIGCGWGTLMLTAAKEYGLHVTGITLSQEQYDYVTQRINDEGLQDVAEVRLEDYRELGNEQWDYITSVGMFEHVGAENLGEYFNCVQKYLMNDGVALIHGITRQQGGANNGWLNKWIFPGGYVPGLVENTTHIIENGLQIDDMEPLRRHYQKTVEIWDQNFNQHREEVAKMFDDKFVRMWDLYLQACAASFKSGNIDVIQYLISKGPSARMLPMTRDYMYAETDKVTD
>NZ_LT854705.1|WP_087742460.1|2206882_2207809_-|hypothetical-protein
MKKWVWVVATIVVALLIGGYAYSNHHATAKEYQAAMTNGRTALKNKDYTQAESYFQNALKRRLNDRTAQTYLTQTQRFVSGENAMDARKFGHAQARYQTVKTTKNGSTVLVNRATKRLKQVKVIRANVAQFKQLLSKAQDQNQALNYGTSNTTLDELFNNSKFQQVYYKNLYAQALALRKANNAGQTSVVTNSSSAATSTTGSGTTTSSSSATTGTTSNSSSNGASLTSSESAAAQNYQGSNEYTVTKKQKELNGKVITAGQISSARQTINAAGGQADAMSDQDVRVALQQANKKGLSLTKYTQQYLK
>NZ_LT854705.1|WP_087742459.1|2205197_2206382_-|ROK-family-protein
MIINKHIMRTTNEKQVLQQIVNAGPISRSQISRNLSLNKVTVSDIYSELLHEGLIREVGHGVSTRNGGRKPVMALLNVDYGYVISINLLRQRFTMLACRLDGKSEDYTSVSTRNVDLTSVLDMIEEHIRQMMGDRDTRLLGLSFGLDGVIYENQILNAGLNGLKDFDLAKYFGDKFNVPVVLENLANEAAIFERDFSGEGVYENLISVTIRDQVSAGIITNGHLYRGHRGEAGVIGKCPLADRYQEQNHETVNHYVSETSVLKRIMAYQKLDRVDVNRIRRDYLGHQPELLAILDEFSYYLAKVLANISSSFAPDAILLNVPILELLPELMDDVRGYVDKLAIPRKAPLLLTKNAKEASLMGGASAIIHRVLALDDLQLTFRNERPVVLEQIES
>NZ_LT854705.1|WP_057733561.1|2203848_2204955_-|AI-2E-family-transporter
MNLWERFTTNIRLRRFVVLAFIILILWLVRSEMNTILLTFIFTFLVLQLVKFVRRHVKIPTQLIVVLTYVIILGGLYWAVTTYLPQIVTSSVHGIEKLYKFYQNPDNDTNQIARWVTNYISTSDLLGQVQNGAKVVLNYVSTIGSFGLTVFMSMILSFFFTIESKQMTAFSQRFLTSTYGWVFQDIKFFADKFINTFGVVLEAQFFIAMCNTVITTAILAIMKMPQLPTLAIMIFILSLVPVAGVIVSVIPLAVLGYSVGGYRYIVYILVMIVVVHALEAYVLNPKFMSSRTELPIFYTFVVLLAGEQLFGVWGLIVGVPIFTFFLDILGVRPVHGLHPGVDVEKLRQYRQTHGKRRHHHDDDQDHSE
>NZ_LT854705.1|WP_157667882.1|2202093_2203656_-|LPXTG-cell-wall-anchor-domain-containing-protein
MRRLRQIIMTSLSAMIMGIIPLAIPVTTQAATTPTANWSVDVNGNITGRDVNNYPNQLTWNVGFNSTGQDLGSASLVNTLSPGQAYVPGSVTATTGTFNADGSFSSTGGHELTPTVTVNGTTTLGQQLTVAFSDVNAPIAVYYRTTPQVSGLNGNWMATAEVAGHASTSQINWDGLTDPDPVKTPTSSSTASSSSSSSSSSSSAPAKAPASSTVTSHATTTVTVGGSGMTDGAGGGVDEDSSSSEPMTDGAGGDVDEDSSNEVDSSSSSHMTDGAGGGVDEDSSNEIDSSSSSHMTDGAGGGVDDSSDESAESSSEPSASSSATMPSEPSVSSSSSSSSSSSSSSVISSSQSSQSSSAPVTVPSESSSQASSTPSVTVPGTSSSSATSSSAVSSMPGISSSAASSSVASSGQGVLAPGMSSSSSAQSSQPVTGGQSATVPANNGTVAGLPQSGTQAAIVGSQSVTQSNAMTSGSAVNAALPVTATGRLPQTNDATNYAGVVFGGLMIIGLGLAFVSRKQP
>NZ_LT854705.1|WP_057733565.1|2201235_2201928_-|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase
MAKLVLIRHGQSEWNLSNQFTGWVDVDLSEKGVEEAKAAGKKVKEAGLEFDYAYTSVLKRAIKTLHYVLEESDQLWVPETKTWRLNERHYGALQGLNKKETAEKYGDDQVHIWRRSYDVLPPLLSADDEGSAVNDRRYADLDPNIIPGGENLKVTLERVMPFWEDQIAPKLLDGKNVIIAAHGNSLRALSKYIERISDDDIMDLEMATGEPVVYDFDDKLNMTNKVKLGK
>NZ_LT854705.1|WP_087742458.1|2200754_2200973_-|hypothetical-protein
MYDVDELLEAKRQIDSTLHKIREVVKTFEAKENPSRYKSQLTLAKRRLKAFGIANQLIEDKLAELENDHGKR
>NZ_LT854705.1|WP_045808046.1|2200455_2200707_-|hypothetical-protein
MATKEVTQVEMMKIIALFRKEGFKGEYEDFQRVSGTDREFFVVMSNEQGIKALFRASLMLNAVQFQYVLDDKHTFVQEDADAS
>NZ_LT854705.1|WP_087741887.1|2198880_2199897_+|IS30-family-transposase
MTHSQINTHKHYQQLSLSDRATIQALRATGDTATVIAQKLHRSKATISREITRGSVTQLDSKRHSHQVYLAETAQAIHDRKRDRTGHHAFLKTGRAFFKALTKELTRKPRVHSVDSFVHFYRDQGKSCPSTTTVYRYIDAGLLELDNMTLPKKLRRRVKGYKNAHKRKNKKIYGDSIELRPAAVNDRTGVGHWEGDLVKGIRSADEPALMTLTERYSRTEIIVKIPDYHADTCLKALQDTINDYGAKEFESITFDNGSEFAKLSEIVGTQIYFAHPYSPWERGTNENTNGLLREYFPKGKSLRDVTLVEVQAVQSALNHRPRRILNYLRPCDYYRRMA
>NZ_LT854705.1|WP_087742456.1|2198485_2198797_-|hypothetical-protein
MNCKLGHFYYGKSWKESIPIANQIDLQKILLVATATFETTDVADAILRNGFDVTALLRINFVGILDLGFKSLQVLRSTVVKSKKIDKLDKDLQDEWDRVYQTI
>NZ_LT854705.1|WP_057733554.1|2209772_2210117_-|AzlD-domain-containing-protein
MSTVNTWTSTQHFWLIILGFFVAFLPRFIPLMLFTKREIPEWFNEWMKFVPVSLFTALVVKDVFIDSKSYQLMFTQVPEMLAAVIVIIIAYRTRSMALSVITGLIGVFLLSMVI
>NZ_LT854705.1|WP_087742461.1|2210135_2210939_-|AzlC-family-ABC-transporter-permease
MNKRRPNPKRVPDPNEPLWRSTLRVAMPLNLSYIPIGLACGILLHAAGFNTLLTGLVSLLIFSGGAQFLIATMLTINSPLLSIVLMLFFLELRYALLSSSLSPYLKGQSNRFLFIFAISLNDENYAINYLKFATDKKWTGKEALMVEHYSLLFWAMSNVIGSLIGSALKIDLGIVNFALTALFLYMIVMQIKNRLTVVICLISGVLAAVCMMITKSTLGLVISTIISSLIGFGLETTLRKRLPDSHWLWKLRGPGAKQSAVESSDGK
>NZ_LT854705.1|WP_087742462.1|2211179_2214491_-|YhgE/Pip-domain-containing-protein
MKMVKGEWSYIRHNRLILISVLAIMFIPFLYSIFFLRSVWDPYGETSELPVAVVNLDKPVTYQGQKLNVGDQTVTNLKKNHQLGWKFVSKQQAAQGLKDRKYYTVITIPKNFSAHAATALDEHPKKMTLTYNTNASANYIAEVMSQVGATKLQNEISAKVTKAYAQATFKLVYQVGKGMDKAATGSAQLKDGTTTLTDGLNTYTTGVKKLDNGLQQMKTSVKPLATGIQQLNDGAATLKSGLTQYTSGVSQYTAGVGQYTSGVGQYSAGVNQYTSGVGQYSAGVNQYTAGVGQYTSGVNQFTSGVSQLSAGMPKLTAGTKQLSTGASSLNSGVYKYVDGVYTLNDGVQKLGAGVGPLKSGVSQLSSGSSALNSGLSKLSDNSSSLNDGASSLASKATELSSSVSQLGTAANMATNQLNQLDLSSLSGLPSQVKALSAGLTQVSQGVDGISKYASDIQQRAKSGSTATPATSAAKTVTKTTTSGADSSSVTAAKDATSAAAATAASLKAAAAKEDNSEEVSALASKLASETAAANDKTGAISTSGTSTTEETKTTGSDSSSSSSSSSDANMTAIANDAAAIANASVQVTGGLGVINKQLATAISSLPDTGNLASQVAELKQFAGAVSQLNAAVNPSSGTSLSQGVDTLTNGVKTYTSGVDSAFNGSTTLNNGLNSLNLQVPTLSDGITQIMNGTAELAKNGKALKSGSSQVSSGAATLNSGLQTAAAGVNKLNANTGKLTAAGNKLNSSTGQLTAAGNKLNSSTGKLTAAGNKLNSSTGQLTAAGNKLNQASPQLTSGASQLAAGTAQLNSKVPTLTSGVNQLADGSAQLNENSPKLVAGAKKLNAGNGKLAKSLKSGADQINDQPLTNKTADMFSSPTKLAHKNYSYVPNYGHALAPYVLSVALYVGALVFNFAFPIRKVSLEGGSATGWFFSKVSIGAVEALAMAVIEPSLMMLGGLTVEHPGQLIILSIVFSEASMFIVMFLSMLLDNPGRFIAMVLLMLQLGGSGGTFPMEVTNHFYNVVHPFLPMTYSILGFRQAITDGMGSGVEWQAVMVLALFTVISLALLFPTMHWLQKKHLMGVSQLDDNQKLQAVEDPTSRRHS
>NZ_LT854705.1|WP_172825284.1|2214931_2216239_-|serine-hydrolase
MVGVVAAVTLLTGGLSTGAVTPTVTAHAATSTTSSTVNLKAKAGIAVDATTGQILYEKNGDQSLPVASMSKLLSIYLVLQAVHAGKLKWDQKITISKPIAKVAENTDLSNVPLRAGHSYTVKALYQASLIYSANGAIEALGSAVAGSPHAFVTQMKAQAKKLGMTNVKIYNACGLTNKQVGDLGYSNVAGKAENEWSAADQAKLAVALLDKYPEVLQTTKITKMWFEKGTKDATKMENWNWMLKGLTASYTKLHVDGLKTGTSDAAGANFTGTAHNNGNRIITVVLHAAHKSETDPSRFQQTQKMMSYVYNNFKTVTYHAGQSITGAKSVTTHDAKTKTAKTALASDVKLWIRNDQVASNITAKPQLKASLTKDNALEAPVAKNQQIGTANLSLKGDQLGFLGNTKTVKVPLKVTQSVEKANVFVRMWRWVVALF
>NZ_LT854705.1|WP_057733599.1|2216310_2217486_-|sensor-histidine-kinase
MKLTTREKSALFMEGVVTVILLLMLNLALLVLIVQAIESNPGLRDGIFIIKRSVVLGPHHYQLWSWENLFIGLMMVGDALVVWWRLIRRYKQMQLHHIIEELHYIANGHFDHRIPFRVSGDVQRVVDSVNALVDSVIHSMDEERAIEKSKDELITNVSHDIRTPLTSIIGYLGLIEDKQYHSETDLLKYTHTAFLKSKQMKSLVDDLFEYTKVRQTDTPLSLTKIDLGAMLEQLAASFELEAQKKGMDIGADVGDTPLMMEADPEKLVRIFNNLVSNALKYGDGGKHINLVAKRVSADELEVRVTNDGPKIPKKSLALIFERFYRVEESRSKETGGTGLGLAIAQSIVALHGGYIYVESDDALTSFVIHLPTVHAHPLAVPQRLKAAGTAN
>NZ_LT854705.1|WP_057733546.1|2217496_2218186_-|response-regulator-transcription-factor
MKILVVDDDKEIAQLLEIYIKNEGYEPLTAYNGKEALTKLHTTPDIALMILDVMMPEMSGIEVIKEVRKDSQIPILILSAKTGDMDKIQGLITGADDYVTKPFNPLEVMARVKSLLRRSQDQVTDDSPDVLDIGTLTINKDSHEVKTIAGKTVSLTALEFGILYLLASHPNRVFSADEIFERVWRQESIVSAKTVMVHVSHLRDKIEEATNGEKVIQTVWGVGYKIESH
>NZ_LT854705.1|WP_087742464.1|2218880_2219447_+|matrixin-family-metalloprotease
MFKQIIKQIAIVSATCALAFTTLGGSVNAAENAKTPTWGAWKTTTITYKTNVSSKYYKGVWKNAVKSWNKVGVVELVPAKSGEKADITLTSSNSLKTKGDDLAGYTNYSYYQKSDNNEIVSATSTLNKKLLNKYNYTKTQRTNVATHEIGHALGLSHSKSEASVMYASERYASIDQQDKVALEQAYNN
>NZ_LT854705.1|WP_057733542.1|2219601_2220741_-|IMP-dehydrogenase
MSNWDTKFAKEGITFDDVLLIPAESHVLPDEVDLSVQLAPNLKLNIPFLSASMDTVTETKMATAMAYNGGLGVIHKNMTTDRQAQMVADVKAIENDAAKHPNAAVDANNHLLVAAAVGVTSDTSERAHALLAAGADAIIIDTAHGHSAGVLRKVAQIREELPDATLIAGNVATGEGTRALFEAGVDVVKVGIGPGSICTTRVVAGVGVPQITAVYDAASVAREFGKPIIADGGMKYSGDIVKAMAAGGNAVMFGSMFAGTDEAPGDVIEDGGKKYKTYRGMGSLAAMEKGSKDRYFQGSVNEANKLVPEGIEARVAYKGSVNDIIFQMIGGLRSGMGYTGSANIQALIDNAQFVKISNAGLRESHPHDVQITKAAPNYK
>NZ_LT854705.1|WP_087742465.1|2221002_2222712_-|hypothetical-protein
MTQLMRRVVTKYWWQLELLSFVVLSLIWILPWGFSGKIYLGDDLGFHLNRIQGLAKDIQLSGNWWQIPAVSTADFSGWGYPINLFYPAAALLPAAWLQTIASGVGGYYVFLVLLNVLTLWVAATVAARLLPSRSQAFLAAVIYGFAQYRFLDFFVRGSLAEGIVFAFLPLIFYGVYSIAAGDYHKWPWLAVGMALIALTHVISLVLSSVGVVIMLSLWGLRRKELRARGLRFGAAAGLAVFLSLSFLGPLVVQLRHVGKLGIAQYTLADSATHLGDLLWNSLNDAVASNAINFGVLLLVTSVLAIIVWRQLRPFDHYCLVLGGIFVFLATNLFPWPLFQGLLGTIQFPWRFLALADFPLALVGARAVMVIARAKTFQRALIVVPVVTAIAVGLSFSASTALYRSVGPNNAKVVTNATYLANATQDTTTDYVAQRGLVSMAAVRTHSIPVMNTQPNGQQPASLQQLAVRPVTNGLVYTLKSTTAQEIKLPQLDYYGYHVFVNGREQMPRLDSNGVVHIHVNAGTSQIRYVYQRTTVQYLTSGLTWLAWLSLIGIGCWRWLQRQRRLTAET
>NZ_LT854705.1|WP_087742466.1|2222749_2224402_-|glycosyltransferase-family-39-protein
MLAKLKAKLNNREYQYLALFALLGFFIMLICSYTSPAFYFDYSPDNNAFFTVGKAMAHGQVLYKDIFEQKGPYIYLLHIIAYLVAQRSFVFIYFYESLTLIASMYLTYRIAKLVLTTPQALLVGILSPALFLYHPYYDYGDTAEFFALPLILSLIYLIMLLVVHHLRVSPRWFFAQGLFVGIEFFSKYTLLGGWIAFYLFMGVYLLRRKKWQMLQRLILWSGAGFLLATVPWLVYFAVVHGLKSFIAVYFLFNTQVYMTSSVSFFANLVQSASLLSQFFLSSVVFFMLGLVGTLAITFRTDILPGAFAKSLYLLVFLGNDIFALYGYSSGNVFQYYQLVYFPFFVLPLIYFCKFFFDRQTIRSDDDALTILATILVSLFLVLGVNNNFTSSRLFPNNASVTDRHTKVPQAPAQTEFGDLMRAQTTGKMTLLNYGSIDMGFYTASGAVPTQYYFQNYNIPAKSDPTILNSQVNAIRHKQVEWVVFNTPAGKSPQAWKGLSYKPGQITDGNLNPGTAQMSKILYRNYRYVAQHTQSFENMNVTYWLFQRKGN

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Crispr_ID: NZ_LT854705_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT854705_9

2359273-2359361

Orphan

Consensus_repeat	Method
CAATGCAGATAAATGCAGATAAA	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of NZ_LT854705_9

>merge|NZ_LT854705|9|2359273-2359361|CRISPRCasFinder
CAATGCAGATAAATGCAGATAAATAACAACACAAAATCCCTACACTGCAACGTTTATCTGCATTACCAATGCAGATAAATGCAGATAAA

>NZ_LT854705|9|9|2359273-2359361|CRISPRCasFinder
CAATGCAGATAAATGCAGATAAA	TAACAACACAAAATCCCTACACTGCAACGTTTATCTGCATTAC
CAATGCAGATAAATGCAGATAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT854705.1\|WP_087742544.1\|2354373_2354901_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_087742546.1\|2357778_2358021_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|377306
NZ_LT854705.1\|WP_015473476.1\|2358048_2358978_-\|IS30-like-element-ISLpl1-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_LT854705.1\|WP_087742543.1\|2352777_2354016_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_157667887.1\|2354203_2354377_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_087742549.1\|2361311_2362682_-\|branched-chain-amino-acid-transport-system-II-carrier-protein	unknown	unknown	gnl\|CDD\|283235
NZ_LT854705.1\|WP_057734492.1\|2365405_2366053_+\|NAD(P)H-hydrate-epimerase	unknown	unknown	gnl\|CDD\|223140
NZ_LT854705.1\|WP_087742553.1\|2370029_2371151_-\|NAD(P)-dependent-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|176239
NZ_LT854705.1\|WP_057734490.1\|2364430_2364757_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_087742548.1\|2359860_2360970_+\|glycerol-dehydrogenase	unknown	unknown	gnl\|CDD\|341449
NZ_LT854705.1\|WP_087741887.1\|2356732_2357749_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_LT854705.1\|WP_191982778.1\|2352047_2352641_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_087742550.1\|2363080_2364406_-\|replication-associated-recombination-protein-A	unknown	unknown	gnl\|CDD\|237355
NZ_LT854705.1\|WP_087742551.1\|2366160_2366712_+\|M15-family-metallopeptidase	unknown	unknown	gnl\|CDD\|350617
NZ_LT854705.1\|WP_087742542.1\|2350702_2351650_-\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NZ_LT854705.1\|WP_057734491.1\|2364916_2365372_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_LT854705.1\|WP_087742552.1\|2368503_2369979_-\|aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143407
NZ_LT854705.1\|WP_087742541.1\|2349495_2350551_-\|zinc-dependent-alcohol-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|176258
NZ_LT854705.1\|WP_087742818.1\|2367200_2368127_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|377396
NZ_LT854705.1\|WP_087742545.1\|2355080_2356388_+\|DNA/RNA-non-specific-endonuclease	unknown	unknown	gnl\|CDD\|164869

Protein	Function_ID	Function_description	E-value
NZ_LT854705.1\|WP_087742542.1\|2350702_2351650_-\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	1.848e-18
NZ_LT854705.1\|WP_015473476.1\|2358048_2358978_-\|IS30-like-element-ISLpl1-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	3.5414e-69
NZ_LT854705.1\|WP_087742550.1\|2363080_2364406_-\|replication-associated-recombination-protein-A	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NZ_LT854705.1\|WP_087742549.1\|2361311_2362682_-\|branched-chain-amino-acid-transport-system-II-carrier-protein	gnl\|CDD\|283235	pfam05525, Branch_AA_trans, Branched-chain amino acid transport protein. This family consists of several bacterial branched-chain amino acid transport proteins which are responsible for the transport of leucine, isoleucine and valine via proton motive force.	1.63639e-120
NZ_LT854705.1\|WP_057734492.1\|2365405_2366053_+\|NAD(P)H-hydrate-epimerase	gnl\|CDD\|223140	COG0062, COG0062, Uncharacterized conserved protein [Function unknown].	1.02672e-49
NZ_LT854705.1\|WP_087742548.1\|2359860_2360970_+\|glycerol-dehydrogenase	gnl\|CDD\|341449	cd08170, GlyDH, Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation. Glycerol dehydrogenases (GlyDH) is a key enzyme in the glycerol dissimilation pathway. In anaerobic conditions, many microorganisms utilize glycerol as a source of carbon through coupled oxidative and reductive pathways. One of the pathways involves the oxidation of glycerol to dihydroxyacetone with the reduction of NAD+ to NADH catalyzed by glycerol dehydrogenases. Dihydroxyacetone is then phosphorylated by dihydroxyacetone kinase and enters the glycolytic pathway for further degradation. The activity of GlyDH is zinc-dependent; the zinc ion plays a role in stabilizing an alkoxide intermediate at the active site.	5.17972e-176
NZ_LT854705.1\|WP_087741887.1\|2356732_2357749_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	8.09877e-67
NZ_LT854705.1\|WP_087742551.1\|2366160_2366712_+\|M15-family-metallopeptidase	gnl\|CDD\|350617	cd14840, D-Ala-D-Ala_dipeptidase_Aad, D-Ala-D-Ala dipeptidase (includes Lactobacillus plantarum Aad peptidase). D-Ala-D-Ala dipeptidase (also known as D-alanyl-D-alanine dipeptidase vanX; VanX; EC 3.4.13.22) is a Zn2+-dependent enzyme that mediates resistance to the antibiotic vancomycin in Enterococci and other bacteria (both Gram-positive and Gram-negative). It is part of a gene cluster that affects cell-wall biosynthesis. The operon triggers the termination of peptidoglycan precursors by D-Ala-(R)-lactate instead of D-Ala-D-Ala dipeptides. The enzyme is stereospecific, as L-Ala-L-Ala, D-Ala-L-Ala and L-Ala-D-Ala are not substrates. This subfamily includes Lactobacillus Aad peptidase and belongs in the MEROPS peptidase family M15, subfamily D.	7.63167e-76
NZ_LT854705.1\|WP_087742553.1\|2370029_2371151_-\|NAD(P)-dependent-alcohol-dehydrogenase	gnl\|CDD\|176239	cd08278, benzyl_alcohol_DH, Benzyl alcohol dehydrogenase. Benzyl alcohol dehydrogenase is similar to liver alcohol dehydrogenase, but has some amino acid substitutions near the active site, which may determine the enzyme's specificity of oxidizing aromatic substrates. Also known as aryl-alcohol dehydrogenases, they catalyze the conversion of an aromatic alcohol + NAD+ to an aromatic aldehyde + NADH + H+. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	0
NZ_LT854705.1\|WP_087742546.1\|2357778_2358021_-\|ATP-binding-protein	gnl\|CDD\|377306	pfam04326, AlbA_2, Putative DNA-binding domain. This family belongs to the AlbA clan of DNA-binding domains.	4.96588e-10
NZ_LT854705.1\|WP_057734491.1\|2364916_2365372_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.83311e-11
NZ_LT854705.1\|WP_087742552.1\|2368503_2369979_-\|aldehyde-dehydrogenase	gnl\|CDD\|143407	cd07088, ALDH_LactADH-AldA, Escherichia coli lactaldehyde dehydrogenase AldA-like. Lactaldehyde dehydrogenase from Escherichia coli (AldA, LactADH, EC=1.2.1.22), an NAD(+)-dependent enzyme involved in the metabolism of L-fucose and L-rhamnose, and other similar sequences are present in this CD.	0
NZ_LT854705.1\|WP_087742541.1\|2349495_2350551_-\|zinc-dependent-alcohol-dehydrogenase-family-protein	gnl\|CDD\|176258	cd08298, CAD2, Cinnamyl alcohol dehydrogenases (CAD). These alcohol dehydrogenases are related to the cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Cinnamyl alcohol dehydrogenases (CAD) reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0
NZ_LT854705.1\|WP_087742818.1\|2367200_2368127_+\|DMT-family-transporter	gnl\|CDD\|377396	pfam04657, DMT_YdcZ, Putative inner membrane exporter, YdcZ. DMT_YdcZ is a family of putative inner membrane exporters from both Gram-positive and Gram-negative bacteria.	2.87171e-33
NZ_LT854705.1\|WP_087742545.1\|2355080_2356388_+\|DNA/RNA-non-specific-endonuclease	gnl\|CDD\|164869	PHA01790, PHA01790, streptodornase.	8.84092e-11

>NZ_LT854705.1|WP_015473476.1|2358048_2358978_-|IS30-like-element-ISLpl1-family-transposase
MSSITYSERIKIETFCELGLSNIQMGVRLNRSPSTISYELSRCQPYQAELAQTDAEYKRSRCGRKTKLSDELKQKILNHLRLSWSPGMIAHEFKLATKSIYNWLNQGRIDFSLNDLPEHGVRQRRNVDQRSKYNQSLGRSIEQRPMMINQRNRIGDFELDTVVGPRGHSKAVLLTLIDRKSRFLWAYRLKDRTTATVNEALTKFLTTFNGPVHSFTVDRGTEFSGLVSLESQYGIKTYYCHAYTPAERGSNERFNRNLRYFYPKGTRFEHISAQDLTTTLLQINQRPLKILDWQTPYQVMLTNLSKNSD
>NZ_LT854705.1|WP_087742546.1|2357778_2358021_-|ATP-binding-protein
MVDYLKQLPIENEHREYKKNKSKLTKDLWETISAFENTDGGVIVLGITEKEGEKSFEITGVQNPQQVLDDCPQFSSQVQR
>NZ_LT854705.1|WP_087741887.1|2356732_2357749_+|IS30-family-transposase
MTHSQINTHKHYQQLSLSDRATIQALRATGDTATVIAQKLHRSKATISREITRGSVTQLDSKRHSHQVYLAETAQAIHDRKRDRTGHHAFLKTGRAFFKALTKELTRKPRVHSVDSFVHFYRDQGKSCPSTTTVYRYIDAGLLELDNMTLPKKLRRRVKGYKNAHKRKNKKIYGDSIELRPAAVNDRTGVGHWEGDLVKGIRSADEPALMTLTERYSRTEIIVKIPDYHADTCLKALQDTINDYGAKEFESITFDNGSEFAKLSEIVGTQIYFAHPYSPWERGTNENTNGLLREYFPKGKSLRDVTLVEVQAVQSALNHRPRRILNYLRPCDYYRRMA
>NZ_LT854705.1|WP_087742545.1|2355080_2356388_+|DNA/RNA-non-specific-endonuclease
MATFITFLGVLSLLIAIGLGGLWTVKKIGHRRTNHQGRNALIALVVAFIFIGMGGGGASTTRTASDKANLDNSSSDSTATTTKFSSAKSSSAKPVKQSAAKPKTAAKEQATTSRNSQVLTKLVSYTKAESAGPTQNYYWKLGKAHTTGFKNLKAGDYHFASDSQGRAGSARAVLTYGEYADSRGSRQGDPLEPGGWPTSNPKVAISYVFTGRTYHGYLYNRSHSIGDSLLGAKSYTSANNFTTGTRPQNVGADQNGGMRYAEETAEDYWKANPNTSHTIQYQTTPLYYHSETIPRGSIVDIHSSDGQLNTAIAVINSAEGIKIDYNTGSNNAKPITTAPRRSSHTTSASAGTHDGNGTGNSGASHQTSTTTHSTAQSGTKSGQWTTAPAGQVYVSESNKYYSQVKNPGNYTLKSESQAQADGATRATRGNQYARP
>NZ_LT854705.1|WP_087742544.1|2354373_2354901_-|hypothetical-protein
MYLNVTQKSRDLFRDYPVVRSIDVAQRAARANPIFSWHATAITARRQRFVLISHDASALCVVLNTADCATQRLADLFWAQLAAQWPQYGLAAADLTTYRHVAGDWQINQLLDHQRVRRLNEQGMYVDFLWQQAITSPLELALLVAQTPPLGRQQPRHQVATIARDLTPTRFRWHP
>NZ_LT854705.1|WP_157667887.1|2354203_2354377_+|hypothetical-protein
MAKLAMTVKAVIVLGLSCILGLLIYNLVTDFQSTVLICLGIAVALWFGHHVWPRRSH
>NZ_LT854705.1|WP_087742543.1|2352777_2354016_-|hypothetical-protein
MTEAQPDLNQYLQEKELGANLLIYRYSPMDIIRPGGTVTLLSPEQRRLTAPVARYQLYEMTGQLYADKVDLVDLQTTIDRLFAGEDLPFVTDTDPDLPATAELIRGASQQGLQVIGTHQTGVGRWDVDDDETRLVKGLTVGGSLDIMTSSDGMYQEIVNQEQAVVATSNGEVKPDEHPYMWTTEFFEIVDATGESLLDQVPLSALGAVLFALQRGLSAATVKRLLLWPRLSREDLAGAQLVLGSNGCSKACLIESVDDLQRVANLPAGEESPENAAFLQFVAEDGRVPLSWPINLADGGDLLHQVAHGMSVDVDQQGRQLSTILSQLADSLGVQIRRYDRQLTDICDIKHFKVAADGHQIEDFQANSRKYKEYHRVETVFDVLNPTTEHLLCYDLTFNELVTFLSRLAQGNN
>NZ_LT854705.1|WP_191982778.1|2352047_2352641_+|hypothetical-protein
MTTLPFTKVDSFAFWRIPANADQAADNQARETLFKTHYVPDDFPTDQLPTDLTAYLAQMPYVLVGMNPGNGLADQPDQSFTNFHGARKSQDYKLAAALYGTALWGAFMTDLSETVDSNPQHVAFNQQVVADLENYLDALGIPADATLIAVGQGAHYQNLVKFAHRPVKTIPHYSPSNNGHWTADNSRQKVLAAINQH
>NZ_LT854705.1|WP_087742542.1|2350702_2351650_-|WYL-domain-containing-protein
MTSQERIVQLLFRLLDGESINFRAEARDYGCSERTMTRDQAVIADALVHETEFEMGYKANTHQHYLDREDQILQAEALALIKLVIGTRALSRAEMQRVTHHLLNMLSLKTQKAVKKTIATTMAAYIPVGADQKILPRLAKFSDYIIDKQAIKFSYQSSVPQGNHPQFQVGRPLSLYFADYYFYVVMYLEDNNRSVVFRLDRFDKVKSLNRQLEVPADKKTDEGALRQKTYLLNGGYELHYRFRYWGYPQTALDKLPKSQVTHRHDDGSVTIEGDLFSQGALLWVLGQGALIKVLAPQTLINDVKATLQKTLAYYD
>NZ_LT854705.1|WP_087742541.1|2349495_2350551_-|zinc-dependent-alcohol-dehydrogenase-family-protein
MTEQAEMMAHLPTQMKAWQVTTPGPIDGPQSPLELVTKPVPQPGPGETLVRILACGVCHTDLHVSEGDLPVHHAHVTPGHEIIGEVVGNGPQTNRFKLGERIGVPWLRWTCGVCRYCRSGRENLCPHSLYTGWDHDGGYAQYVTVPEGFAYQIPERFDSVTAAPLLCAGIIGYRAFERANVPAGGTLGLYGFGGSAHITAQIAIDQGIQVHVFTRGKDAQKFGLQLGAASAQGAYDPSPVKLDSAIMFAPVGDMVPNELANLAKGGTLALAGIHLSDIPALNYQDHIFHEKNLTSVESNTRRDGEEFLTLADRLDIYPATTPYAFEKADEALRFVKQGDIKGACVLKIGED
>NZ_LT854705.1|WP_087742548.1|2359860_2360970_+|glycerol-dehydrogenase
MTTAFASPSTYVQGDQLLEHAAPYITPFGDHGLLLADDIVWQLIGQKFYDNLTTANLTIEHVQFNGESSPEEIDRIKAIGQRTDAKFVIALGGGKTNDTTKAVGDALGIPVVIVPTLASNDSPCTRLSVLYSADGEFLKYLFYDKNPDLVLVDSAVIAGAPVRFLIDGIADALSTNVESQSVSWARETTLLPLNTQQTAAGIALAEKCEEILFKYTDQAVAAASDHVVTPALEHIIEANILLSGVGAESSGLAAAHSFQNGLTALSGDVHKLSHGQKVAFGTLVNLVLEGASDARFRKYLDFEVALGLPTTFADLHLGDATDADLLKVAELATQEGETIHNMGFPVDARTLLAAMKGADALSRNFQHLN
>NZ_LT854705.1|WP_087742549.1|2361311_2362682_-|branched-chain-amino-acid-transport-system-II-carrier-protein
MEQTDKRHNFWQLLVVSSLIFGMFFGSGNLIFPVHLGQMAGQNWFTAALGFAVSGSLFPLLAILAVVVTKSDGLYDLAKPVSAKYAAVFLVLVHLTIGPFFGTPRTAATAYQMAAEPFLPKQWTTLGQWLFTAAFFALAYVLATHQNSLVKVVGKYLNAGFLALLAVVFVVAFLKPMGNVAHTPTVAYQTNASISGLLEGYNTIDAVALLALSVTFVHAVRGLGYRDKELTRLTAKSGTLSIVLEVLVYFGLVLLGTLSLGQLKLSDNGGVALSQIVGHYFSNFGTAFLGVLVTLGVFTTALGLVTSFAQDFHKLFPKVSYLAWLRVTTVASFLVANAGLDNIIAWSLPVLMLLYPMSLALILVSLTVAKKPYASVVYKTTIAVTAVPAVLDMLANAPAVVATFGPVAAVLHAYHTYVPFASLGLGWLVPTGLAFFLSLAWGHFRLVAQESAERAR
>NZ_LT854705.1|WP_087742550.1|2363080_2364406_-|replication-associated-recombination-protein-A
MEQESLFDNPQQMPLANRVRPETLDDFVGQRHLLGPGKILRELIENDQVSSMIFWGPPGVGKTTLAEIIAQQTQAKFIRFSAVDSSIRKIKQVMQLAEGDREIGERTLVFVDEIHRFNKAQQDAFLPYVERGSIILIGATTENPSFELNSALLSRCKVFVLKALETSDIEQLLTNALKNPAGFPDLTVQVGPDELRAIAEFANGDARTALNTLEMAVLNGQKTDQRVTVTMDDLKQLITQKFVLYDKSGEEHYNIISALHKSMRNSDADAAIYWLSRMLEGGEDPLYIARRLVRFASEDIGLADTNALNVAVNVFQACQFLGMPECDVHLTEAVTYLALAPKSNAIYKARLAAKKDVKETRDEPVPLQIRNAPTKLMADLDYGKDYQYAHDTPDKLTTMQSLPDALVGHEYYHPTDQGREDLFKKRLDYVKKWRREHSSKS
>NZ_LT854705.1|WP_057734490.1|2364430_2364757_-|hypothetical-protein
MFIQIPTDMDEVQLRQLQLKKLGEDVSEDDVIRQGVLDTFQTFLDQIEDGHYDTAKWQDEQLIVIDILGKQTATVAPMSDSFLSDFRTNAEATQQYLEQQAERAAGGR
>NZ_LT854705.1|WP_057734491.1|2364916_2365372_+|MarR-family-transcriptional-regulator
MEDYILDFTTNLAILHRQFQRDMNQILEADKVPINITEFYLLVLVSETSPINQRMAARTIAVDEGLMTRMVRHLVALDFLQKTDDPTDRRNKQLTLTATGEQLVQRAIQVLHHWWQNVTPTDTTVNFQAMTEQLQRLSMRVLQFDHPLENL
>NZ_LT854705.1|WP_057734492.1|2365405_2366053_+|NAD(P)H-hydrate-epimerase
MSKAITIAQAQSYDAHTINEIGIPAMVLMERAALATFNNLLNDDYDLTRVVVVAATGNNGGDGIAVARLLKVRNIDVAIYLLGDPTKATDQTAQQLKIANYYHIPFTTDLNDVINATTIIDAIFGVGLSRPITGKFAEAVNAINATDASTVAIDVPSGINADSGETLGVAVMADSTTTMAYKKVGMLTANGKQHTGILHVADIGIYGADHVETIK
>NZ_LT854705.1|WP_087742551.1|2366160_2366712_+|M15-family-metallopeptidase
MSKLTGFSNIQTLDPTLLVDLRYATPNNFTGQVIYDFTTAIARTGTAQKLVAANAALRQQGYRLKVWDAYRPVTAQRRLFDVYPDPNFVAQPDSNFSHQKGVTFDLTLCDAAGHELEMQSAFDDFSERAHREYPRTAEQEHNYQLLNQAMLAAGFVGYINEWWDYRDADQNTYAPLAANPNDF
>NZ_LT854705.1|WP_087742818.1|2367200_2368127_+|DMT-family-transporter
MGVIIGLILPLQTSINSRLRRSVGSPFVASLISFTIGTLFLAVVTLGVDHQLFFSPHLFSQQPAWLWIGGFFGVVYLTCNILLFPQLGSVQTVILPMFGQILMGLLIDNFGLFHAKVSPLTPIRLAGAILVLIGVVVTVALSTWLFNRHEARTTSTQAARGLWLWRLLGIFAGMLGAAQSAINGHLGLVLHSSLNAAFISFFVGTLALIVINLVLRSPRQLIEPDHRPNPWWMWLGGVIGALFVLGNVYLVPILGTGLTVVIVLVGLMGGSLLIDNFGWLDSKRNPVTLVQIVGLLIMIGGVALIHLA
>NZ_LT854705.1|WP_087742552.1|2368503_2369979_-|aldehyde-dehydrogenase
MPATETGLKHYQMYVNGEFKDSTSGKLLTVINPSTGEKISTVPSATREETQEAINDAYEAEKTWKFVPAATRGQYLHDVATEVRNQADHLIALLQEEQGKIKSLATTEIMFSADYFDYMAAAARTYEGEILQSDNKHENIMIAKQPIGVAAGILPWNFPFFLIARKMGPALVTGNTIVMKPSSDTPNLALEFAKIVDKVGIPKGVVNFVTGPGSVVGDELSRNKKIGIISLTGSVDSGKRVMAAASTHMAKVSLELGGKAPAIVCSDADLDLAAQAIIDSRIDNNGQLCNNCERIYVQEDVADEFTKKLTAKMAAVKVANPITDKDSGMGPLINQAALDKVDGMVQRAVKAGGKITTGGHKVTIENGFYYEPTVITNVKQDSEIVQDEIFGPVLPIVTYKTLDDAINMANDSDFGLTSSIFTQNLDNAARAANELEDGETYINRFNFEAMNGSHSGWKESGIGGDDGRHGIEEYLNTHVIYLQGHPEKAQG
>NZ_LT854705.1|WP_087742553.1|2370029_2371151_-|NAD(P)-dependent-alcohol-dehydrogenase
MRIKAAVVDKKGGSFEIKDDVELAPMQADDLQVHMVATGICHSDEALRKGDAEIGYPIILGHEGSGIVEKVGPEVKDFKPGDHVILSFYGCGNCTNCLKGMPTQCLNYAANNLSGVRPDGSAHFTENGHDVADMFDQSSFTTTTAVRERNAVKVPKDLDLRKLGPLGCGYVTGSGTVLNTLKPKPGDTIAVFGTGAVGLAAMMAGKISGCTTVIAVDVVDSRLALAKELGATDTINSKTENAVEAIKKLTDGHGVDWAVDTTGVKQVMEDSIQALAQGGTTATIAVTPHHIDLDTWNDLCVSDRKVVGVNMGDSVPQIDIPRLIRFYRAGMFDFDKTEKFYRFDQINEANADSGSGKTIKPVLVIDPDYVPGK

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Crispr_ID: NZ_LT854705_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT854705_10

2420171-2420255

Orphan

Consensus_repeat	Method
CCAATCTTCTGGTGCCGAAACGTGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LT854705_10

>merge|NZ_LT854705|10|2420171-2420255|CRISPRCasFinder
CCAATCTTCTGGTGCCGAAACGTGTTCGCCCAGGCAGCCAGTTGCGCTTAACCCCACGCACCAATCTTCTGGTGCCGAAACGTGT

>NZ_LT854705|10|10|2420171-2420255|CRISPRCasFinder
CCAATCTTCTGGTGCCGAAACGTGT	TCGCCCAGGCAGCCAGTTGCGCTTAACCCCACGCA
CCAATCTTCTGGTGCCGAAACGTGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT854705.1\|WP_087742819.1\|2417932_2418688_+\|YdcF-family-protein	unknown	unknown	gnl\|CDD\|99750
NZ_LT854705.1\|WP_087742589.1\|2423904_2424903_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|234672
NZ_LT854705.1\|WP_057731725.1\|2408122_2410510_-\|phosphoketolase-family-protein	unknown	unknown	gnl\|CDD\|235379
NZ_LT854705.1\|WP_087741887.1\|2420973_2421990_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_LT854705.1\|WP_087742592.1\|2426452_2427454_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NZ_LT854705.1\|WP_021355909.1\|2422709_2423900_-\|NarK/NasA-family-nitrate-transporter	unknown	unknown	gnl\|CDD\|340899
NZ_LT854705.1\|WP_057731719.1\|2412089_2412593_+\|Cys-tRNA(Pro)-deacylase	unknown	unknown	gnl\|CDD\|237976
NZ_LT854705.1\|WP_087742582.1\|2412596_2413403_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_087742590.1\|2425194_2425596_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|238385
NZ_LT854705.1\|WP_011101425.1\|2424946_2425192_-\|MoaD/ThiS-family-protein	unknown	unknown	gnl\|CDD\|340452
NZ_LT854705.1\|WP_087742591.1\|2425993_2426449_+\|flavodoxin	unknown	unknown	gnl\|CDD\|180922
NZ_LT854705.1\|WP_087742594.1\|2428337_2429408_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238562
NZ_LT854705.1\|WP_087742584.1\|2414321_2415527_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340874
NZ_LT854705.1\|WP_087742587.1\|2418736_2419981_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227245
NZ_LT854705.1\|WP_087742586.1\|2417531_2417780_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT854705.1\|WP_003640267.1\|2429424_2430831_-\|Fe-S-cluster-assembly-protein-SufB	unknown	unknown	gnl\|CDD\|131035
NZ_LT854705.1\|WP_087742585.1\|2415498_2416332_+\|carboxylating-nicotinate-nucleotide-diphosphorylase	unknown	unknown	gnl\|CDD\|238806
NZ_LT854705.1\|WP_087742593.1\|2427450_2428221_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224045
NZ_LT854705.1\|WP_057731722.1\|2411185_2411911_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_LT854705.1\|WP_087742583.1\|2413454_2414216_+\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|223979

Protein	Function_ID	Function_description	E-value
NZ_LT854705.1\|WP_087742819.1\|2417932_2418688_+\|YdcF-family-protein	gnl\|CDD\|99750	cd06259, YdcF-like, YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been idenitified. The family also includes Escherichia coli sanA and Salmonella typhimurium sfiX, which are involved in vancomycin resistance; sfiX may also be involved in murein synthesis.	2.76149e-09
NZ_LT854705.1\|WP_087742589.1\|2423904_2424903_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|234672	PRK00164, moaA, GTP 3',8-cyclase MoaA.	3.51763e-155
NZ_LT854705.1\|WP_003640267.1\|2429424_2430831_-\|Fe-S-cluster-assembly-protein-SufB	gnl\|CDD\|131035	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB. This protein, SufB, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_LT854705.1\|WP_087741887.1\|2420973_2421990_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	8.09877e-67
NZ_LT854705.1\|WP_087742592.1\|2426452_2427454_+\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	4.96594e-67
NZ_LT854705.1\|WP_021355909.1\|2422709_2423900_-\|NarK/NasA-family-nitrate-transporter	gnl\|CDD\|340899	cd17341, MFS_NRT2_like, Plant Nitrate transporter NRT2 family and Bacterial Nitrate/Nitrite transporters of the Major Facilitator Superfamily. This family is composed of plant NRT2 family high-affinity nitrate transporters as well as nitrate and nitrite transporters from bacteria including Bacillus subtilis nitrate transporter NasA and nitrite extrusion protein NarK, Staphylococcus aureus NarT, Synechococcus sp. nitrate permease NapA, Mycobacterium tuberculosis NarK2 and nitrite extrusion protein NarU. NRT2 family proteins are involved in the uptake of nitrate by plant roots from the soil through the high-affinity transport system (HATS). There are seven Arabidopsis thaliana NRT2 proteins, called AtNRT2:1 to AtNRT2:7. The NRT2-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.66874e-102
NZ_LT854705.1\|WP_057731719.1\|2412089_2412593_+\|Cys-tRNA(Pro)-deacylase	gnl\|CDD\|237976	cd00002, YbaK_deacylase, This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS) inserted (INS) editing domain. The bacterial amino acid trans-editing enzyme YbaK is a deacylase that hydrolyzes cysteinyl-tRNA(Pro)'s mischarged by prolyl-tRNA synthetase. YbaK also hydrolyzes glycyl-tRNA's, alanyl-tRNA's, seryl-tRNA's, and prolyl-tRNA's. YbaK is homologous to the INS domain of prolyl-tRNA synthetase (ProRS) as well as the trans-editing enzyme ProX of Aeropyrum pernix which hydrolyzes alanyl-tRNA's and glycyl-tRNA's.	2.1299e-58
NZ_LT854705.1\|WP_057731725.1\|2408122_2410510_-\|phosphoketolase-family-protein	gnl\|CDD\|235379	PRK05261, PRK05261, phosphoketolase.	0
NZ_LT854705.1\|WP_087742590.1\|2425194_2425596_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|238385	cd00756, MoaE, MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. Moco contains a tricyclic pyranopterin, termed molybdopterin (MPT), which carries the cis-dithiolene group responsible for molybdenum ligation. This dithiolene group is generated by MPT synthase in the second major step in Moco biosynthesis. MPT synthase is a heterotetramer consisting of two large (MoaE) and two small (MoaD) subunits.	2.29021e-50
NZ_LT854705.1\|WP_011101425.1\|2424946_2425192_-\|MoaD/ThiS-family-protein	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	1.9187e-20
NZ_LT854705.1\|WP_087742591.1\|2425993_2426449_+\|flavodoxin	gnl\|CDD\|180922	PRK07308, PRK07308, flavodoxin; Validated.	1.04338e-43
NZ_LT854705.1\|WP_087742594.1\|2428337_2429408_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238562	cd01142, TroA_e, Periplasmic binding protein TroA_e. These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind their ligands in the cleft between these domains.	5.09878e-101
NZ_LT854705.1\|WP_087742584.1\|2414321_2415527_+\|MFS-transporter	gnl\|CDD\|340874	cd17316, MFS_SV2_like, Metazoan Synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters of the Major Facilitator Superfamily. This family is composed of metazoan synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters including those that transport inorganic phosphate (Pht), aromatic compounds (PcaK and related proteins), proline/betaine (ProP), alpha-ketoglutarate (KgtP), citrate (CitA), shikimate (ShiA), and cis,cis-muconate (MucK), among others. SV2 is a transporter-like protein that serves as the receptor for botulinum neurotoxin A (BoNT/A), one of seven neurotoxins produced by the bacterium Clostridium botulinum. BoNT/A blocks neurotransmitter release by cleaving synaptosome-associated protein of 25 kD (SNAP-25) within presynaptic nerve terminals. Also included in this family is synaptic vesicle 2 (SV2)-related protein (SVOP) and similar proteins. SVOP is a transporter-like nucleotide binding protein that localizes to neurotransmitter-containing vesicles. The SV2-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.91315e-67
NZ_LT854705.1\|WP_087742587.1\|2418736_2419981_-\|hypothetical-protein	gnl\|CDD\|227245	COG4908, COG4908, Uncharacterized protein containing a NRPS condensation (elongation) domain [General function prediction only].	3.2491e-21
NZ_LT854705.1\|WP_087742585.1\|2415498_2416332_+\|carboxylating-nicotinate-nucleotide-diphosphorylase	gnl\|CDD\|238806	cd01572, QPRTase, Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with 5-phosphoribosyl-1-pyrophosphate (PRPP) in the presence of Mg2+ to produce nicotinic acid mononucleotide (NAMN), pyrophosphate and carbon dioxide. QPRTase functions as a homodimer with two active sites, each formed by the C-terminal region of one subunit and the N-terminal region of the other.	1.45244e-117
NZ_LT854705.1\|WP_087742593.1\|2427450_2428221_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	5.21711e-77
NZ_LT854705.1\|WP_057731722.1\|2411185_2411911_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.40205e-58
NZ_LT854705.1\|WP_087742583.1\|2413454_2414216_+\|NUDIX-hydrolase	gnl\|CDD\|223979	COG1051, COG1051, ADP-ribose pyrophosphatase [Nucleotide transport and metabolism].	9.83211e-13

>NZ_LT854705.1|WP_087742587.1|2418736_2419981_-|hypothetical-protein
MNQNPLNILHTIGLKELYPIIRCQIKLTGPFDIDRFRRAVTLSAKVVPELFCKYNLADNSWTPVVDDATTMVTVVDQLTPGLDSNPDWFRQPQLRVFIEPGTTTTLVLTMSHILTDGSGFKQYLYLLSDCYNRGVAAVKDVHNTVELDWLKDLLKTHPAPQQKKDVDHPAHALGLPRLADESAQREAHVSGVRLSAVLTKQLIHATHDQHVTVNDVLMATFGKTIQAYDPEVADIAIACPTDMRQSIDHDQAQFRIANHTARYNPSIPAPLAEPIRESVQKMHAGMAALKGQDQFLDSVRSLMAQYQHESIDQLQQIVEANYHVRPIGYTNFGIIDDQRLRLDDTDITDVLMTGSFRFAPMYQIACSTFKGQLSLGFNMVGTDQEVQFGRDLAQTMAGRIEDFIDPQTASTQTL
>NZ_LT854705.1|WP_087742819.1|2417932_2418688_+|YdcF-family-protein
MADALNVLADYLGPRDVPELTRAALNEPLDAIILFGGSILAGDSVFHEAMAHQAANHYLIAGGRGHTTPTLRAQLSKRGFDFLGDPSEALMHQRYLEYTYVDHIRLLETESTNCGSNVANSLAILQAHDIPVKRLGIIQDATMQRRMAACFHKVAPETQLVNFAAYQVHVQVWNGQLGFTKPIFGMWSMHDYITLLMGELPRLTDDAHGYGPHGQNYIAHVDIPEPVQAAYAFLQAHLDITGRPADPAFKS
>NZ_LT854705.1|WP_087742586.1|2417531_2417780_+|hypothetical-protein
MFTLTNVENTELKKVKAIELKGHVYKMRLSKVIALIVVAVVVSGAFVSTQAFAASNSNPATANHSFSSAYTALVQKQSQALK
>NZ_LT854705.1|WP_087742585.1|2415498_2416332_+|carboxylating-nicotinate-nucleotide-diphosphorylase
MTLSPKRLTERLATFLEEDLATGDLSTSALPPQVVHGDFTAKRAGILVGQCIPAAVYQLLSSQATYTPTVPDGTLVSAGTVVGHATGPATTLLAGERVVLNLMQRMSGIATATHLAVDALNDPSIGILDTRKTAPGLRLFDKYAVQCGGGLNHRMGLYDAVMLKDNHLRLITDLPATVQRLRQLIGPTKLIEVEVETLNQLQLAITSRVDMIMFDNQSPTTVREWRQLVPPTIQVEASGGITPAKLPSYAGTGVDFISLGYLTNSVQALDISFNLTD
>NZ_LT854705.1|WP_087742584.1|2414321_2415527_+|MFS-transporter
MSKSKYHLLFVVGTAWLFDAMDVAILSFIMPLLKTEWQLSPVQLGTVGAATSVGMIIGALVCGYLADRIGRKRVLIYTLALFSCGNLALTLAPNVTIFILIRFITGIGLGGELPVAATLIADSYRGTQRSRMLVMADSFWAIGWILASVLAFGAMPVIGWRWTVLITALTVLYALPLRKHLPDTPVKPMVKPSYKVLWQPEHRQQTLLLSALWFIVMLTYYGMFLWLPSILVLRGFPIIHSFNYTLLMSLAQLPGYYLAAYLMGRLRQKTVLLIYLCGTIVSVLAFSMATSNSAILVSGAWLSFFDLGAWGTLIALTPGQFPQAIRGTGMGTAQSIGRVGATIGPYLVGLLIQLKFSISTVLGLFVVLLVFGALLLAVGVVDSTVPSKEAADHDAKSETTH
>NZ_LT854705.1|WP_087742583.1|2413454_2414216_+|NUDIX-hydrolase
MTAPTITITNLIWSFDRTTQHVNLLLLKRDQAPFKAYWALPTTTMRDDESADAAALRLVREKIGLALDRLHTEQLATFTQPQRTPGPRGVALAYMTFLPEMPPLTPGYGASAAKWFQFADTPTAYQLQNGTAAFITPTSDQATYYATPAARTTTPLTQLAFDHDWMIAVASQRIRNKLDYQPNILLTLGPTFTLREARTVFATFLRCPLNALDNSNFKKNHRQLFTAVGTTTAKRAGRPATLYRLNYLPLTNA
>NZ_LT854705.1|WP_087742582.1|2412596_2413403_+|hypothetical-protein
MTVDYALLVKNLALIVFWLLVLPGAFIALLTGVNRNTKQYLANGFGINSELYLGFIGIFFHELSHLIVALLFGHHITQFRLLKRPHPHQRTANGEKDLALGYVNHTWNQSSWYQSTGNLFIGIAPIFGCSLVLLGLTAWLLPDLFSGLVTVVSQPLNLHWEGLREVVVGAHDPWWHWLLMGLLAMNISVGGFDLSSADFANSQRGLIGFIILIMVVTAGWTLIDGATGWLRGVAVVMTLLTVVLTCSLLISLVTNFFVRIVLHVKWHH
>NZ_LT854705.1|WP_057731719.1|2412089_2412593_+|Cys-tRNA(Pro)-deacylase
MSKKKKAKRLHKTLVEQILDKNKIAYQQYEFATHMAGDTAQMEVDHAAVDEHHIYKTLVLSGNVTGPLVGVLPIDEHLDEKKLAKASGNKKVDMIPLKNLVKTTGYEHGANTPVGIWEKKQFPIFIDNTAHEQGQILVSSGQIGRSVEVNADELAGLVHGTFTDLLE
>NZ_LT854705.1|WP_057731722.1|2411185_2411911_-|GntR-family-transcriptional-regulator
MADLVYRQVMRDLKRRIHQNEFPNKRLPDERSLSEAYGVSRSSVKRALSILANQGIIFKKRGSGTFINPLYMKNQTIFQYEGSNLGITDSMKSAGNTPGIRLLGFNVVPASKEIQQDLFLSPGDFVYEIKRLRLFNDQPFMIETGYIPIKIAPNLSQQTVASSIFNYLESQGKVVTKSFMSIQAAPSTADDQDLLKLKPVEPVGIMEGIFFLDDGTPFEVSNMRLHYRYLNYNTFVSLDEE
>NZ_LT854705.1|WP_057731725.1|2408122_2410510_-|phosphoketolase-family-protein
MAANTNFDSKAYLEGVDKYWRAANYLSVGQLFLRDNPLLKRDLTSDDVKIKPIGHWGTIVSQNFIYAHLNRVIQKYNLNMFYIEGSGHGGQVMVSNSYLDGSYSEIYPNISQDEEGLKRLFKQFSFPGGVASHAAPETPGSIHEGGELGYSLSHGTGAILDNPDVIAAVEIGDGESETGPLAASWFSDKFINPIKDGAVLPIINMNGFKISNPTILSRMSDKELTEYFTGMGWEPHFVEIDENDTDYMRVTEDMAKTMDEAIEKIKAIQKNARENNDETLPQWPMIVFRSPKGWTGPKHDLDGNPIEGSFRAHQVPIPVAAGDMEHADLLVNWLKSYKPEELFNEDGSVKAEIRDMAPKGDQRMAMNPITNGGIKPEPLKMPDYKKFAVDVKEHGKTIAQDMLVWSDYLAEMMKLNPNNFRGFGPDETKSNRLYAALDYGKRQWMEDIHEPNDENMAHEGRIIDSQLSEHQAEGWLEGYVLTGRHGFFATYESFGRVVDSMLTQHMKWLRKAGEQSWRHDYPSLNFVDTSTVFQQDHNGYTHQDPGMLTHLAEKKPELIREYLPADANTLLAVGNVAFQSRSKINLIVTSKHPRPQWFTIDEATNLVNNGLGYIDWASTDQGQEPDIVFAAAGTEPTWESLAAISLLHDEFPEMKIRFINVVDILKLRSPKLDPRAISDEEFDRLFTTDKPIIFAWHGFEDMIKGLFFDRHNHNLHVHGYRENGDITTPFDMRVLNQLDRFDLAKEAVNDIPEYAVKGAYFVQRMDDMVAKHTAYIREVGTDLPEVNNWEWKPLK
>NZ_LT854705.1|WP_087741887.1|2420973_2421990_+|IS30-family-transposase
MTHSQINTHKHYQQLSLSDRATIQALRATGDTATVIAQKLHRSKATISREITRGSVTQLDSKRHSHQVYLAETAQAIHDRKRDRTGHHAFLKTGRAFFKALTKELTRKPRVHSVDSFVHFYRDQGKSCPSTTTVYRYIDAGLLELDNMTLPKKLRRRVKGYKNAHKRKNKKIYGDSIELRPAAVNDRTGVGHWEGDLVKGIRSADEPALMTLTERYSRTEIIVKIPDYHADTCLKALQDTINDYGAKEFESITFDNGSEFAKLSEIVGTQIYFAHPYSPWERGTNENTNGLLREYFPKGKSLRDVTLVEVQAVQSALNHRPRRILNYLRPCDYYRRMA
>NZ_LT854705.1|WP_021355909.1|2422709_2423900_-|NarK/NasA-family-nitrate-transporter
MTVEDAQTSTRWRAYLALGLATVAMIVCFMSWSNFAPLAGELAIKFHLSVSQRTLLLATPVLLGSIMRIPVGILSDRYGGKKVYLILMAFILIPLLMITKVHTYGMLLVAALLVGMAGTSFAVGVSYASVWFPPEKQGLALGIVSMGNMGNAVAALTLPSISTSYGFNMVYYFLMVLTVILAVLFAIFCREMPVDKTKTVTGALAVAKESSTWYLSLFYFLTFGLFVSFTNLTPLFLEDIFRVPQVTAGLYAALFAGLCTVVRPIGGAAADKWRPMQMLQWIFIGITVFAVIITLTFSNQSLFIFGIVGAGLIAGFGNGVIFKMVPYVSQGNTGAVTGFVGALGGLGGFFPPLLVGWIHTWTGSYRLGIVLLALTGLVCWYALWRRFIHGDVHIVK
>NZ_LT854705.1|WP_087742589.1|2423904_2424903_-|GTP-3',8-cyclase-MoaA
MEKLYDSYDRLHDYVRLSITDRCNLRCVYCMPKEGLPFFPTDRVLSQDEIVQLIENFAAMGVSKVRITGGEPLLRTDVVEIVRRIKAVDGINDVSITTNGLFLAKLAKPLKESGLDRLNISLDTFKADRYKKITRGGNIQQVLDGIAVASKLHFKKIKLNIVLIKGQNDDEVLDFLHYTKDHDVNARFIEFMPIGNSLKTWQKEYVGLKNVFDTCKDNGLAYHPIVLRGNGPSDNYQIEGYEGSFGLIHPISSKFCENCNRLRITADGYVKACLYWNEEIDIRSAIGDPVAFRKLIQKALDNKPLNHEMAMSETDRIIDKAPTWRHMSQIGG
>NZ_LT854705.1|WP_011101425.1|2424946_2425192_-|MoaD/ThiS-family-protein
MELTIKLFAMLAEQIGPTVTVTVSTPATAAMVKPALSQRTPALKAVINNARIAVNQEFIADDRQVLQSTDEIALIPPVSGG
>NZ_LT854705.1|WP_087742590.1|2425194_2425596_-|molybdenum-cofactor-biosynthesis-protein-MoaE
MAMIKLSATPLDVNALYQVLKAPEYGGIVTFVGTVRQWTGPIETQSIDYSAYAEMAISQLNKLAAPIEAKGARVVIVHRIGHLDLMDEAVFVGVAAAHRADAFEWCQYLIDTLKKEVPIWKKEFDTDKVRWGD
>NZ_LT854705.1|WP_087742591.1|2425993_2426449_+|flavodoxin
MKAEIIYASLTGNNEEIAEIIQNQLREHHVDTNLTEIGQADAFDLPVADLIVIVPYTYGEGDLPEEGLDFFDDLQDVDLSGTVFGVAGSGDRWYAEDYCKAVVKFDHQLETTGATRGVQPLFIDLHPEDADEQRLDDFTTSLIKTATQLGV
>NZ_LT854705.1|WP_087742592.1|2426452_2427454_+|iron-ABC-transporter-permease
MIKTRRRGYGILLLTTLALIGLMLVALSLGRYQLSLSDLIATLTGQASVSPVIHNIVFSLRLPRILAAAAIGAALAISGTAYQSIFQNPLVSPDLLGISNGAAVGAALAILLGWHTVGTQILAFALGLIAVLLSVGIPRLIHQSSTLALVLAGIVISGLMQAILGLLKYLADPESQLQDIVYWQLGSLAKVNLNSLGDVLPLLIVGMVILLTMRWRLTVLALGNQVAFAQGINVRLERGLVILSATMLTASAVCLSGTIGWIGLIVPHMARIIIGENTKWSLPLSGLIGAIFLLVVDTLARTLSAGEIPLSILTGFIGTPIFIAILLSKKVAL
>NZ_LT854705.1|WP_087742593.1|2427450_2428221_+|ABC-transporter-ATP-binding-protein
MTALLSAEHLAFHYPKQADLFTDLQLQLHHGEILTLLGPNGIGKSTLLECLLGLLTPTAGTLTLNGQPLATLTPKQRARIIAYVPQTIPTTTSLSVRDYLLTGRTPYLNFAQSPGATDVALADRILKTLQLSELTAHTINTLSGGQAQLVTIARALMQEPELIILDEPTAALDFGRQQQLLSLVQQLAGQNIAVILTTHNPNHALILKQRVGLFGASGHFDYGGIELLTEPRLRATYQTKLRLLYVPELGRTICEF
>NZ_LT854705.1|WP_087742594.1|2428337_2429408_-|ABC-transporter-substrate-binding-protein
MKKTRRILLGLALIIGLSVGAGCRSTASKSKTANASQSATTRTVTDMAVTKVKIPTKVTRVADLWHANNQVVLLLGGQKKLVATTQMIKQSPWFKTIDLGISKVTAPFAGDDLQTEELLKAKPDVVIAADTAQVKQARKAKIPTINAMYQTFAGLRQSVNLTAKVLGGTAPKIAKAYQKTLTTNLNDVKTRLKDVTSKPKVLHFVNATNLNQVDGTGTIVNEWIKAAGGQNALKQKGNMISVTTETLAKSDPDVIIVGSATTAEARAALKKNAVLSKLTAVKKNRVYGNPQGTFPWDRYSAEEALQVLWAAKKLHPDQFQDLNMVAKTKAFYQQFYHYQLSTAQANRLLNGASSPK
>NZ_LT854705.1|WP_003640267.1|2429424_2430831_-|Fe-S-cluster-assembly-protein-SufB
MSEVPDVVKNDRDYEYGFHDDVKPAYSTGRGLTEATVREISAAKHEPQWMLDYRLNAYHEYLKMPMPKFGPDLTKLDLKDMLYYQKMTDKKFRDWKEVPADLKRTFDRLGVPEAERKYLAGSSAQYESEVVYHNMRKDFEKLGIIFTDTDTALHDYPELFKKWFGKLVKPTDNKFAALNAAVWSGGSFIYVPKGVQTKTPIQSYFRLNAENSGQFERTLIIVEDGASVDYVEGCTAPNYSSDSLHAAVVEVNVEPNAYCRYTTIQNWSDNVYSLETKRAAAAENATMEWVDGNLGSKVTMKYPSVYLNGEGARGTMLSIAVASNGIHQDSGARMIHNAKNTSSSIVSKSIAKTGGATDYRGTVRFAKHSDGSKAHVECDTIIMDDQSSSNTIPYNEIDSANVAMEHEAKVSKISEEQLYYLMSRGISEAKATEMIIMGFVEPFTKQLPMEYAVELNRLISFEMEGSIG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LT854705_6	6.2\|1224855\|31\|NZ_LT854705\|PILER-CR,CRT	1224855-1224885	31	MW147367	Synechococcus phage S-H9-2, complete genome	135509-135539	4	0.871
NZ_LT854705_1	1.1\|185914\|30\|NZ_LT854705\|PILER-CR,CRT	185914-185943	30	NZ_LT604075	Lactobacillus salivarius isolate LPM01 plasmid II	193086-193115	6	0.8
NZ_LT854705_3	3.3\|816700\|33\|NZ_LT854705\|CRISPRCasFinder	816700-816732	33	CP054927	Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence	194478-194510	6	0.818
NZ_LT854705_1	1.4\|186112\|30\|NZ_LT854705\|PILER-CR,CRT	186112-186141	30	NZ_CP021457	Lactobacillus brevis strain ZLB004 plasmid p1, complete sequence	53307-53336	7	0.767
NZ_LT854705_1	1.4\|186112\|30\|NZ_LT854705\|PILER-CR,CRT	186112-186141	30	NZ_CP012290	Pediococcus damnosus strain TMW 2.1535 plasmid pL21535-2, complete sequence	48506-48535	7	0.767
NZ_LT854705_5	5.2\|901695\|33\|NZ_LT854705\|CRT	901695-901727	33	NC_008573	Shewanella sp. ANA-3 plasmid unnamed1, complete sequence	157156-157188	8	0.758
NZ_LT854705_6	6.1\|1224794\|31\|NZ_LT854705\|PILER-CR,CRT	1224794-1224824	31	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	551771-551801	8	0.742
NZ_LT854705_6	6.2\|1224855\|31\|NZ_LT854705\|PILER-CR,CRT	1224855-1224885	31	MK170160	Acinetobacter phage TAC1, complete genome	28253-28283	8	0.742
NZ_LT854705_6	6.2\|1224855\|31\|NZ_LT854705\|PILER-CR,CRT	1224855-1224885	31	NZ_KY349138	Mycolicibacterium sp. CBMA 213 plasmid pCBMA213_2, complete sequence	7184-7214	8	0.742
NZ_LT854705_1	1.1\|185914\|30\|NZ_LT854705\|PILER-CR,CRT	185914-185943	30	NZ_CP024792	Nostoc flagelliforme CCNUN1 plasmid pNFSY07, complete sequence	231780-231809	9	0.7
NZ_LT854705_2	2.1\|378159\|33\|NZ_LT854705\|PILER-CR,CRISPRCasFinder,CRT	378159-378191	33	KT716399	Pseudomonas phage POR1, complete genome	42017-42049	9	0.727
NZ_LT854705_4	4.1\|845400\|34\|NZ_LT854705\|CRISPRCasFinder	845400-845433	34	NZ_CP029234	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436d, complete sequence	50148-50181	9	0.735
NZ_LT854705_6	6.1\|1224794\|31\|NZ_LT854705\|PILER-CR,CRT	1224794-1224824	31	NZ_CP054613	Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence	1930959-1930989	9	0.71
NZ_LT854705_8	8.3\|2209513\|37\|NZ_LT854705\|CRISPRCasFinder	2209513-2209549	37	CP024783	Lactobacillus johnsonii pf01 plasmid pLJPF01S, complete sequence	13091-13127	9	0.757
NZ_LT854705_8	8.6\|2209514\|36\|NZ_LT854705\|CRT	2209514-2209549	36	CP024783	Lactobacillus johnsonii pf01 plasmid pLJPF01S, complete sequence	13092-13127	9	0.75
NZ_LT854705_2	2.4\|378342\|33\|NZ_LT854705\|PILER-CR,CRISPRCasFinder,CRT	378342-378374	33	NZ_CP016287	Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence	956731-956763	10	0.697
NZ_LT854705_5	5.11\|901697\|33\|NZ_LT854705\|CRISPRCasFinder	901697-901729	33	NC_008573	Shewanella sp. ANA-3 plasmid unnamed1, complete sequence	157158-157190	10	0.697
NZ_LT854705_4	4.2\|845462\|33\|NZ_LT854705\|CRISPRCasFinder	845462-845494	33	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	271069-271101	11	0.667

1. spacer 6.2|1224855|31|NZ_LT854705|PILER-CR,CRT matches to MW147367 (Synechococcus phage S-H9-2, complete genome) position: , mismatch: 4, identity: 0.871

tggtaaaattgctggttcagttcgtcggtaa-	CRISPR spacer
tggtaaaattggtggttcagtt-gacgttaat	Protospacer
*********** ********** * ** ***

2. spacer 1.1|185914|30|NZ_LT854705|PILER-CR,CRT matches to NZ_LT604075 (Lactobacillus salivarius isolate LPM01 plasmid II) position: , mismatch: 6, identity: 0.8

acaaccttaaataaaccagcaaggttctta	CRISPR spacer
actacctaaaataaaccagcaagttatata	Protospacer
** **** *************** * . **

3. spacer 3.3|816700|33|NZ_LT854705|CRISPRCasFinder matches to CP054927 (Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.818

ccagctcggcgccagatgctatctggctaactg---	CRISPR spacer
cgagctcggcgccagaggcgatctgg---actggtc	Protospacer
* ************** ** ******   ****

4. spacer 1.4|186112|30|NZ_LT854705|PILER-CR,CRT matches to NZ_CP021457 (Lactobacillus brevis strain ZLB004 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.767

ccaaaaaaggggcgattgctctctttgcta	CRISPR spacer
caaaaaaaggggccattgcgctcttcagca	Protospacer
* *********** ***** *****.. .*

5. spacer 1.4|186112|30|NZ_LT854705|PILER-CR,CRT matches to NZ_CP012290 (Pediococcus damnosus strain TMW 2.1535 plasmid pL21535-2, complete sequence) position: , mismatch: 7, identity: 0.767

ccaaaaaaggggcgattgctctctttgcta	CRISPR spacer
caaaaaaaggggccattgcgctcttcagca	Protospacer
* *********** ***** *****.. .*

6. spacer 5.2|901695|33|NZ_LT854705|CRT matches to NC_008573 (Shewanella sp. ANA-3 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

tatcatcagccatttctaaccattgagttgttc	CRISPR spacer
tatttgcagccatttctaaaaattgagttgaag	Protospacer
***.  *************  *********

7. spacer 6.1|1224794|31|NZ_LT854705|PILER-CR,CRT matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 8, identity: 0.742

acgcgaccagcggcccgcacgaagaagctat	CRISPR spacer
acgcgacccgcggccggcacgaaaccgcggc	Protospacer
******** ****** *******.  ** ..

8. spacer 6.2|1224855|31|NZ_LT854705|PILER-CR,CRT matches to MK170160 (Acinetobacter phage TAC1, complete genome) position: , mismatch: 8, identity: 0.742

tggtaaaattgctggttcagttcgtcggtaa	CRISPR spacer
tggtaaaactgctggtacagttcagttctta	Protospacer
********.******* ******. .  * *

9. spacer 6.2|1224855|31|NZ_LT854705|PILER-CR,CRT matches to NZ_KY349138 (Mycolicibacterium sp. CBMA 213 plasmid pCBMA213_2, complete sequence) position: , mismatch: 8, identity: 0.742

tggtaaaattgctggttcagttcgtcggtaa	CRISPR spacer
ccgtaaaattgctggtcaagttcgttattca	Protospacer
. **************. *******.. * *

10. spacer 1.1|185914|30|NZ_LT854705|PILER-CR,CRT matches to NZ_CP024792 (Nostoc flagelliforme CCNUN1 plasmid pNFSY07, complete sequence) position: , mismatch: 9, identity: 0.7

acaaccttaaataaaccagcaaggttctta	CRISPR spacer
gcaaccttaattaaaccagcaatgccagag	Protospacer
.********* *********** *..   .

11. spacer 2.1|378159|33|NZ_LT854705|PILER-CR,CRISPRCasFinder,CRT matches to KT716399 (Pseudomonas phage POR1, complete genome) position: , mismatch: 9, identity: 0.727

tacccccgtcgacttcgtcaaacgccttatctg	CRISPR spacer
tttcgccgttgacttcctcaaacgccttacgga	Protospacer
* .* ****.****** ************.  .

12. spacer 4.1|845400|34|NZ_LT854705|CRISPRCasFinder matches to NZ_CP029234 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436d, complete sequence) position: , mismatch: 9, identity: 0.735

tccccggccttaattgccttgaccgcttgactga	CRISPR spacer
ctctggcttttaattgccttgacagcttggctga	Protospacer
..*. * ..************** *****.****

13. spacer 6.1|1224794|31|NZ_LT854705|PILER-CR,CRT matches to NZ_CP054613 (Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence) position: , mismatch: 9, identity: 0.71

acgcgaccagcggcccgcacgaagaagctat	CRISPR spacer
ctccagccagcggcccgcactaagcagctcc	Protospacer
 . *..************** *** **** .

14. spacer 8.3|2209513|37|NZ_LT854705|CRISPRCasFinder matches to CP024783 (Lactobacillus johnsonii pf01 plasmid pLJPF01S, complete sequence) position: , mismatch: 9, identity: 0.757

attcgttttcattgccacttgcttagacacacggaat	CRISPR spacer
attaagttccattgtcacttgcttagacacacttatg	Protospacer
*** . **.*****.*****************  *

15. spacer 8.6|2209514|36|NZ_LT854705|CRT matches to CP024783 (Lactobacillus johnsonii pf01 plasmid pLJPF01S, complete sequence) position: , mismatch: 9, identity: 0.75

ttcgttttcattgccacttgcttagacacacggaat	CRISPR spacer
ttaagttccattgtcacttgcttagacacacttatg	Protospacer
** . **.*****.*****************  *

16. spacer 2.4|378342|33|NZ_LT854705|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016287 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.697

cgatgcgcagaccggcccccgtcaggaacttgt	CRISPR spacer
cgatcggcagaccggcccccgtcaacatagccc	Protospacer
****  ******************. *   . .

17. spacer 5.11|901697|33|NZ_LT854705|CRISPRCasFinder matches to NC_008573 (Shewanella sp. ANA-3 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.697

tcatcagccatttctaaccattgagttgttcgt	CRISPR spacer
tttgcagccatttctaaaaattgagttgaagtg	Protospacer
*.  *************  *********

18. spacer 4.2|845462|33|NZ_LT854705|CRISPRCasFinder matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 11, identity: 0.667

tatccccgtcttctgggtcttctgtttccatgt	CRISPR spacer
gggatccgtcttctccgtcttctgtttccggac	Protospacer
 .  .*********  *************. ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

24294 : 53325

unidentified_phage(23.08%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087741233.1\|24294_24750_+\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	5.1e-18	37.0
WP_087741234.1\|24906_26382_-	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_087741235.1\|26498_27107_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_087741236.1\|27346_28741_+	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	1.2e-129	54.4
WP_087741238.1\|28912_29872_+\|transposase	IS30 family transposase	H7BW61	unidentified_phage	2.0e-19	33.5
WP_087741239.1\|30021_31791_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.8e-101	40.1
WP_087741240.1\|32347_33610_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	3.7e-50	33.2
WP_015473476.1\|33886_34816_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_087741241.1\|34857_35337_-	methylated-DNA--[protein]-cysteine S-methyltransferase	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	3.6e-14	38.8
WP_087741242.1\|36104_37280_+	MFS transporter	NA	NA	NA	NA
WP_057732921.1\|37344_37620_+	hypothetical protein	NA	NA	NA	NA
WP_087741243.1\|38078_39701_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_087741244.1\|40774_41491_+	response regulator transcription factor	W8CYM9	Bacillus_phage	6.1e-42	40.1
WP_087741245.1\|41535_43392_+	cell wall metabolism sensor histidine kinase WalK	W8CYF6	Bacillus_phage	6.0e-33	34.1
WP_087741246.1\|43378_44671_+	hypothetical protein	NA	NA	NA	NA
WP_057732910.1\|44695_45550_+	two-component system regulatory protein YycI	NA	NA	NA	NA
WP_057732908.1\|45956_46772_+	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	1.1e-34	35.7
WP_083485311.1\|47005_48349_+	trypsin-like peptidase domain-containing protein	W5SAB9	Pithovirus	1.6e-06	26.2
WP_087741247.1\|49377_49857_+	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_087741248.1\|49952_50753_+	abortive infection family protein	NA	NA	NA	NA
WP_015473476.1\|51223_52153_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_010620880.1\|52299_53325_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	2.3e-42	36.1

DBSCAN-SWA_2

85936 : 145947

unidentified_phage(25.0%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015473476.1\|85936_86866_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_057730357.1\|86943_87261_-	multidrug efflux SMR transporter	NA	NA	NA	NA
WP_087741280.1\|87526_89134_+	sodium:proton antiporter	NA	NA	NA	NA
WP_087741281.1\|89272_89938_+	type 1 glutamine amidotransferase	NA	NA	NA	NA
WP_087741282.1\|89991_90222_-	PLDc N-terminal domain-containing protein	NA	NA	NA	NA
WP_087741283.1\|90387_91743_+	threonine/serine exporter family protein	NA	NA	NA	NA
WP_087741284.1\|91834_92674_+	metallophosphoesterase family protein	NA	NA	NA	NA
WP_087741285.1\|92804_93176_+	cupredoxin domain-containing protein	NA	NA	NA	NA
WP_087741286.1\|93190_93454_+	cupredoxin domain-containing protein	NA	NA	NA	NA
WP_087741287.1\|93450_95376_+	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	8.3e-102	39.2
WP_057730341.1\|95517_96408_+	DMT family transporter	NA	NA	NA	NA
WP_087741288.1\|97277_97841_+\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_087741289.1\|98203_99598_+\|tRNA	asparagine--tRNA ligase	M1PB22	Moumouvirus	3.9e-77	36.2
WP_087741290.1\|99709_101119_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_087741291.1\|101815_102625_+	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_087741292.1\|102596_103127_+	ECF transporter S component	NA	NA	NA	NA
WP_087741293.1\|103123_103681_+	TIGR01440 family protein	NA	NA	NA	NA
WP_157667830.1\|104087_104225_+	hypothetical protein	NA	NA	NA	NA
WP_157667831.1\|104258_104417_+	hypothetical protein	NA	NA	NA	NA
WP_172825233.1\|104444_104708_+	hypothetical protein	NA	NA	NA	NA
WP_087741295.1\|104984_105233_+	hypothetical protein	NA	NA	NA	NA
WP_087741296.1\|105409_106666_+\|tRNA	tyrosine--tRNA ligase	A0A1L2CUL7	Pectobacterium_phage	2.4e-81	41.1
WP_087741297.1\|106865_108752_+	tyrosine decarboxylase	NA	NA	NA	NA
WP_087741298.1\|109090_110491_+	amino acid permease	NA	NA	NA	NA
WP_015473476.1\|110585_111515_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_087741299.1\|111790_113236_+	Na+/H+ antiporter NhaC	NA	NA	NA	NA
WP_087741300.1\|113525_115616_+	hypothetical protein	NA	NA	NA	NA
WP_087741301.1\|115870_116710_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_087741302.1\|116910_117591_-\|protease	matrixin family metalloprotease	G9I094	Helicoverpa_zea_nudivirus	1.5e-05	52.2
WP_087742762.1\|119874_120567_+	VTT domain-containing protein	NA	NA	NA	NA
WP_087741303.1\|120605_121400_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_087741304.1\|121502_122180_-	type 1 glutamine amidotransferase domain-containing protein	NA	NA	NA	NA
WP_087741305.1\|122344_123859_+	LytTR family transcriptional regulator	D0R0A3	Streptococcus_phage	9.9e-34	28.0
WP_087741306.1\|123855_124299_+	hypothetical protein	NA	NA	NA	NA
WP_087741307.1\|124467_125988_+	MFS transporter	NA	NA	NA	NA
WP_172825234.1\|126452_130145_+	MucBP domain-containing protein	NA	NA	NA	NA
WP_015473476.1\|131749_132679_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_087741309.1\|132791_133517_-	hypothetical protein	NA	NA	NA	NA
WP_087741310.1\|133984_134737_+	hypothetical protein	NA	NA	NA	NA
WP_087741311.1\|134832_135933_-	family 20 glycosylhydrolase	NA	NA	NA	NA
WP_087741312.1\|136112_137144_-	aldehyde reductase	NA	NA	NA	NA
WP_087741313.1\|137281_137839_+	TetR/AcrR family transcriptional regulator	A0A1X9I6A2	Streptococcus_phage	9.3e-06	35.4
WP_057734503.1\|138185_138887_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.1e-31	35.5
WP_087741314.1\|138897_141471_+	ABC transporter permease	NA	NA	NA	NA
WP_087741315.1\|141577_142555_+	aldo/keto reductase	NA	NA	NA	NA
WP_087741316.1\|142619_143414_-	type I methionyl aminopeptidase	A0A1V0SIN6	Klosneuvirus	6.6e-05	26.9
WP_087741317.1\|143644_143926_+	hypothetical protein	NA	NA	NA	NA
WP_087741318.1\|144264_145947_-\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.3e-103	40.2

DBSCAN-SWA_3

153155 : 206730

unidentified_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015473476.1\|153155_154085_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_157667832.1\|154094_154478_-	hypothetical protein	NA	NA	NA	NA
WP_157667833.1\|155074_155530_+	hypothetical protein	NA	NA	NA	NA
WP_057734532.1\|155595_156969_-	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_015473476.1\|157318_158248_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_087741328.1\|158347_159292_-	3-hydroxyacyl-CoA dehydrogenase family protein	NA	NA	NA	NA
WP_087741329.1\|159429_160323_-	hypothetical protein	NA	NA	NA	NA
WP_087741330.1\|160471_161695_-	MFS transporter	NA	NA	NA	NA
WP_087741331.1\|161957_162668_+	orotidine-5'-phosphate decarboxylase	NA	NA	NA	NA
WP_087741332.1\|162671_163313_+	orotate phosphoribosyltransferase	S4VS55	Pandoravirus	1.6e-33	39.6
WP_087741333.1\|163405_164185_-	hypothetical protein	NA	NA	NA	NA
WP_087741334.1\|164299_164725_-	hypothetical protein	NA	NA	NA	NA
WP_087741335.1\|164898_165828_+\|transposase	IS30 family transposase	H7BW61	unidentified_phage	5.0e-20	29.9
WP_057734576.1\|166037_166778_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_087741336.1\|166796_167228_-	HIT domain-containing protein	NA	NA	NA	NA
WP_087741337.1\|167241_168555_-	MFS transporter	NA	NA	NA	NA
WP_087741338.1\|168712_169588_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_057734585.1\|169601_170120_+	hypothetical protein	NA	NA	NA	NA
WP_087741339.1\|170220_171597_+	FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	2.2e-11	26.1
WP_057734589.1\|171836_173738_+	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_087742763.1\|174128_174794_-	aquaporin family protein	NA	NA	NA	NA
WP_087741887.1\|175085_176102_-\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	1.4e-36	32.8
WP_087741342.1\|176672_178565_+	beta-galactosidase	L0N6M2	Herpes_simplex_virus	9.0e-101	35.7
WP_087741343.1\|178545_179511_+	beta-galactosidase	NA	NA	NA	NA
WP_087741344.1\|179730_183783_+	type II CRISPR RNA-guided endonuclease Cas9	NA	NA	NA	NA
WP_087741345.1\|183991_184897_+	type II CRISPR-associated endonuclease Cas1	NA	NA	NA	NA
WP_087741346.1\|184874_185180_+	CRISPR-associated endonuclease Cas2	NA	NA	NA	NA
WP_157667834.1\|185176_185842_+	type II-A CRISPR-associated protein Csn2	NA	NA	NA	NA
WP_087741348.1\|186401_187325_-	ribokinase	NA	NA	NA	NA
WP_157667835.1\|187439_187799_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_087741350.1\|187907_188885_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_157667836.1\|189023_189857_-\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_087741352.1\|190120_191284_+\|transposase	transposase	Q5ULQ4	Lactobacillus_virus	2.1e-145	65.6
WP_087741353.1\|191616_192045_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_087742764.1\|192098_192686_+	hypothetical protein	NA	NA	NA	NA
WP_087741354.1\|192993_193314_+	hypothetical protein	NA	NA	NA	NA
WP_087741355.1\|193414_194131_+	class I SAM-dependent methyltransferase	A0A097BYE1	Leuconostoc_phage	5.5e-43	38.5
WP_087741356.1\|194212_195145_+	pyrimidine-specific ribonucleoside hydrolase RihA	NA	NA	NA	NA
WP_157667836.1\|196883_197717_+\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_147007841.1\|198026_199757_-	aryl-sulfate sulfotransferase	NA	NA	NA	NA
WP_087742765.1\|200139_201315_+	acyltransferase	NA	NA	NA	NA
WP_057734630.1\|201250_202759_+	AMP-binding protein	Q75ZG1	Hepacivirus	1.9e-29	28.9
WP_087741357.1\|202782_203910_+	glycerate kinase	W6LM47	Streptococcus_phage	2.8e-25	36.3
WP_157667836.1\|204341_205175_+\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_087741358.1\|205313_205769_-	hypothetical protein	NA	NA	NA	NA
WP_015473476.1\|205800_206730_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9

DBSCAN-SWA_4

326846 : 385400

unidentified_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015473476.1\|326846_327776_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_157667899.1\|328278_329175_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	1.4e-19	28.1
WP_087741439.1\|329706_330273_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_087741440.1\|330566_331985_+	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_057731662.1\|332126_332876_+	glucose 1-dehydrogenase	NA	NA	NA	NA
WP_087741441.1\|333027_335334_+	DUF4968 domain-containing protein	NA	NA	NA	NA
WP_083485270.1\|335441_336821_-	Nramp family divalent metal transporter	NA	NA	NA	NA
WP_087741442.1\|337310_338165_+	DegV family protein	NA	NA	NA	NA
WP_087741443.1\|338830_340573_+\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.4e-103	40.2
WP_087741444.1\|340572_341472_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_057731684.1\|342016_343423_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_057731687.1\|343551_343878_+	thioredoxin	A0A1J0GW78	Streptomyces_phage	5.3e-17	43.0
WP_057731690.1\|343877_344141_+	metal-sensitive transcriptional regulator	NA	NA	NA	NA
WP_087741445.1\|344339_345143_+	hypothetical protein	NA	NA	NA	NA
WP_087741446.1\|345196_346192_-	LCP family protein	NA	NA	NA	NA
WP_057731694.1\|346393_346867_+	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_087741447.1\|347083_348187_+	hypothetical protein	NA	NA	NA	NA
WP_087741448.1\|348336_349698_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_057733806.1\|349687_350581_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_087741449.1\|350593_351451_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_057733802.1\|351797_352643_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_057733800.1\|352642_353020_+	DUF1634 domain-containing protein	NA	NA	NA	NA
WP_087741450.1\|353229_354441_+	MFS transporter	NA	NA	NA	NA
WP_057733796.1\|354452_355145_+	GTP pyrophosphokinase family protein	NA	NA	NA	NA
WP_087741451.1\|355193_356108_-	AEC family transporter	NA	NA	NA	NA
WP_087741452.1\|356326_356527_-	YjzD family protein	NA	NA	NA	NA
WP_057733786.1\|356781_357975_+	cation:proton antiporter	NA	NA	NA	NA
WP_057733784.1\|358194_358374_+	hypothetical protein	NA	NA	NA	NA
WP_087741453.1\|358538_361259_-	YfhO family protein	NA	NA	NA	NA
WP_057733781.1\|362162_362855_+	response regulator transcription factor	NA	NA	NA	NA
WP_087741454.1\|362844_364155_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_087741240.1\|364202_365465_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	3.7e-50	33.2
WP_087741455.1\|365722_366688_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_087741456.1\|367235_368606_+	SLC45 family MFS transporter	NA	NA	NA	NA
WP_087741457.1\|368733_371007_+	glycoside hydrolase family 65 protein	NA	NA	NA	NA
WP_087741458.1\|371066_371579_-	hypothetical protein	NA	NA	NA	NA
WP_057733768.1\|371807_372077_-	30S ribosomal protein S14	NA	NA	NA	NA
WP_087741459.1\|372205_373237_-	galactose mutarotase	NA	NA	NA	NA
WP_087741460.1\|373528_374344_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_087741461.1\|374380_375199_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_057733759.1\|375453_375837_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_087741462.1\|375986_377834_+	SH3-like domain-containing protein	NA	NA	NA	NA
WP_057733755.1\|379027_379456_+	Spx/MgsR family RNA polymerase-binding regulatory protein	NA	NA	NA	NA
WP_087741463.1\|379511_380288_-	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	5.3e-15	41.3
WP_087741464.1\|380772_383058_+	MucBP domain-containing protein	NA	NA	NA	NA
WP_087742768.1\|383267_384284_+\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	4.2e-36	32.5
WP_015473476.1\|384470_385400_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9

DBSCAN-SWA_5

388967 : 438807

Staphylococcus_phage(18.18%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087741468.1\|388967_389966_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.5e-51	38.1
WP_057733746.1\|390108_391038_+	L(+)-tartrate dehydratase subunit alpha	NA	NA	NA	NA
WP_087741469.1\|391037_391649_+	L(+)-tartrate dehydratase subunit beta	NA	NA	NA	NA
WP_057733742.1\|391862_393281_+	anion permease	NA	NA	NA	NA
WP_087741470.1\|393380_394100_+	SDR family oxidoreductase	A0A0M4JSW6	Mollivirus	4.6e-05	36.7
WP_087741471.1\|394187_394934_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_087741472.1\|395162_396020_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_087741473.1\|396026_396476_+	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_087741474.1\|396663_402771_+	KxYKxGKxW signal peptide domain-containing protein	NA	NA	NA	NA
WP_087741475.1\|402937_403279_+	hypothetical protein	NA	NA	NA	NA
WP_087741476.1\|403377_404334_-	Dyp-type peroxidase	S4VXK8	Pandoravirus	1.7e-18	29.0
WP_015473476.1\|404447_405377_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_057733722.1\|405493_405862_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_087741478.1\|405908_406559_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_087742769.1\|406662_406935_-	hypothetical protein	NA	NA	NA	NA
WP_087741479.1\|407315_409175_+	KxYKxGKxW signal peptide domain-containing protein	NA	NA	NA	NA
WP_172825235.1\|409892_416786_+	hypothetical protein	NA	NA	NA	NA
WP_087741481.1\|417007_417824_+\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	2.0e-25	49.5
WP_087741482.1\|418184_420047_-	tannase	NA	NA	NA	NA
WP_087742770.1\|420335_421352_+\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	6.4e-37	33.6
WP_087741483.1\|421533_422487_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	3.7e-10	22.3
WP_057733713.1\|422674_423430_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.2e-33	37.9
WP_087741484.1\|423444_425268_+	ABC transporter permease	NA	NA	NA	NA
WP_057733709.1\|425298_425667_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_087741485.1\|425945_426350_+	iron-sulfur cluster biosynthesis family protein	NA	NA	NA	NA
WP_087742771.1\|426544_427876_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_057733705.1\|428040_429576_+	multicopper oxidase domain-containing protein	NA	NA	NA	NA
WP_087741486.1\|430056_430743_+	hypothetical protein	NA	NA	NA	NA
WP_057733701.1\|430987_431884_-	DMT family transporter	NA	NA	NA	NA
WP_087741487.1\|432120_432690_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_087741488.1\|432824_433265_-\|transposase	IS200/IS605 family transposase	A0A0P0IQC6	Lactobacillus_phage	2.6e-35	55.9
WP_087741489.1\|433358_434621_+\|transposase	transposase	A0A286QQE5	Streptococcus_phage	1.9e-54	35.8
WP_172825236.1\|435097_435253_+	hypothetical protein	NA	NA	NA	NA
WP_087741490.1\|435370_435559_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_087741491.1\|435562_436090_+	DUF3278 domain-containing protein	NA	NA	NA	NA
WP_057733690.1\|436138_436663_+	DUF3278 domain-containing protein	NA	NA	NA	NA
WP_057733688.1\|436715_437747_-	putative sulfate exporter family transporter	NA	NA	NA	NA
WP_015473476.1\|437877_438807_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9

DBSCAN-SWA_6

582190 : 637904

unidentified_phage(20.0%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087741580.1\|582190_583120_+\|transposase	IS30 family transposase	H7BW61	unidentified_phage	6.5e-20	29.9
WP_087741581.1\|583213_584239_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	3.0e-42	36.1
WP_087741582.1\|584922_585465_+	bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR	NA	NA	NA	NA
WP_087741583.1\|585628_586570_+	aspartate carbamoyltransferase catalytic subunit	M1I6M4	Paramecium_bursaria_Chlorella_virus	1.5e-27	31.5
WP_087741584.1\|586566_587844_+	dihydroorotase	NA	NA	NA	NA
WP_087741585.1\|587845_588931_+	carbamoyl phosphate synthase small subunit	R4TGJ8	Halovirus	1.4e-53	34.9
WP_087741586.1\|588930_592107_+	carbamoyl-phosphate synthase large subunit	NA	NA	NA	NA
WP_087741587.1\|592502_593420_+	dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_057731265.1\|593549_594257_+	class A sortase	NA	NA	NA	NA
WP_087741588.1\|594735_595161_+	hypothetical protein	NA	NA	NA	NA
WP_157667836.1\|595211_596045_-\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_087741589.1\|596228_596954_+	WxL domain-containing protein	NA	NA	NA	NA
WP_087741590.1\|597021_597738_+	WxL domain-containing protein	NA	NA	NA	NA
WP_087741591.1\|597875_598907_+	DUF916 and DUF3324 domain-containing protein	NA	NA	NA	NA
WP_057731253.1\|598995_599607_-	LysE family transporter	NA	NA	NA	NA
WP_087741592.1\|599816_600275_-	low molecular weight phosphotyrosine protein phosphatase	NA	NA	NA	NA
WP_057731248.1\|600382_600961_+	LemA family protein	NA	NA	NA	NA
WP_087741593.1\|600969_601863_+\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
WP_057731243.1\|601938_602724_+	hypothetical protein	NA	NA	NA	NA
WP_087741594.1\|602989_604402_+	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase	NA	NA	NA	NA
WP_087741595.1\|604576_606142_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	6.6e-73	39.7
WP_087741596.1\|606426_606999_+	hypothetical protein	NA	NA	NA	NA
WP_087741597.1\|607271_608273_-	diaminopimelate epimerase	NA	NA	NA	NA
WP_087741598.1\|608269_609646_-	aspartate kinase	NA	NA	NA	NA
WP_087741599.1\|610111_611413_+	diaminopimelate decarboxylase	NA	NA	NA	NA
WP_087741600.1\|611428_612133_+	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase	NA	NA	NA	NA
WP_057731221.1\|612129_613278_+	N-acetyldiaminopimelate deacetylase	NA	NA	NA	NA
WP_057731218.1\|613291_614182_+	4-hydroxy-tetrahydrodipicolinate synthase	NA	NA	NA	NA
WP_087741601.1\|614178_614955_+	4-hydroxy-tetrahydrodipicolinate reductase	NA	NA	NA	NA
WP_087741602.1\|615137_616334_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_057731208.1\|616373_617426_+	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_057731207.1\|617633_618350_-	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	A0A2P9FI75	Pseudomonas_phage	1.1e-06	43.1
WP_087741603.1\|618636_618999_+	holo-ACP synthase	NA	NA	NA	NA
WP_087741604.1\|618998_620126_+	alanine racemase	NA	NA	NA	NA
WP_057731202.1\|620208_620436_+	hypothetical protein	NA	NA	NA	NA
WP_057731200.1\|620462_620879_+	type II toxin-antitoxin system PemK/MazF family toxin	A0A291I9M9	Lactobacillus_phage	6.7e-09	35.1
WP_057731199.1\|620959_621601_-	CBS domain-containing protein	NA	NA	NA	NA
WP_015473476.1\|621696_622626_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_087741606.1\|622871_624260_-	peptidoglycan binding domain-containing protein	NA	NA	NA	NA
WP_087741607.1\|624783_625749_-	L-lactate dehydrogenase	NA	NA	NA	NA
WP_057731194.1\|626047_626605_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_087741608.1\|626622_630180_+	transcription-repair coupling factor	NA	NA	NA	NA
WP_087741609.1\|630313_631894_+	polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_057731190.1\|631895_632168_+	RNA-binding S4 domain-containing protein	NA	NA	NA	NA
WP_057731189.1\|632330_632747_+	septum formation initiator family protein	NA	NA	NA	NA
WP_057731187.1\|633086_633647_+	RNA-binding protein S1	NA	NA	NA	NA
WP_087741610.1\|633733_635119_+\|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA
WP_057731184.1\|635111_635654_+	hypoxanthine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	4.5e-13	29.7
WP_087741611.1\|635765_637904_+\|protease	ATP-dependent zinc metalloprotease FtsH	C7U047	Ostreococcus_tauri_virus	6.2e-106	48.2

DBSCAN-SWA_7

684812 : 745842

Streptococcus_phage(21.05%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_057732384.1\|684812_686303_+\|tRNA	glutamate--tRNA ligase	NA	NA	NA	NA
WP_087741640.1\|686835_688251_+\|tRNA	cysteine--tRNA ligase	A0A2K9L6B7	Tupanvirus	3.8e-43	33.1
WP_057732380.1\|688247_688652_+	Mini-ribonuclease 3	NA	NA	NA	NA
WP_057732378.1\|688651_689404_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_057732377.1\|689428_689995_+	NYN domain-containing protein	NA	NA	NA	NA
WP_057732375.1\|690066_690630_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_083485291.1\|690702_690852_+	50S ribosomal protein L33	NA	NA	NA	NA
WP_057732373.1\|690883_691060_+	preprotein translocase subunit SecE	NA	NA	NA	NA
WP_057732371.1\|691173_691725_+	transcription termination/antitermination protein NusG	NA	NA	NA	NA
WP_057732369.1\|691976_692402_+	50S ribosomal protein L11	NA	NA	NA	NA
WP_057732367.1\|692500_693199_+	50S ribosomal protein L1	NA	NA	NA	NA
WP_057732366.1\|693421_693928_+	50S ribosomal protein L10	NA	NA	NA	NA
WP_024747613.1\|693989_694355_+	50S ribosomal protein L7/L12	NA	NA	NA	NA
WP_172825266.1\|694650_697269_+	bifunctional lysylphosphatidylglycerol flippase/synthetase MprF	NA	NA	NA	NA
WP_087741641.1\|697405_697945_+	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_087741642.1\|697990_698569_-	TIGR00730 family Rossman fold protein	A0A1G5S9X4	Enterococcus_phage	1.3e-21	35.7
WP_057732360.1\|698631_699570_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_087741643.1\|699711_701973_+	5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase	NA	NA	NA	NA
WP_087741644.1\|701976_702840_+	methylenetetrahydrofolate reductase [NAD(P)H]	NA	NA	NA	NA
WP_087741240.1\|702984_704247_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	3.7e-50	33.2
WP_087742776.1\|704353_705352_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	3.4e-115	63.2
WP_057732354.1\|705382_707548_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	2.5e-256	61.2
WP_087741645.1\|707642_707870_-	redoxin NrdH	A0A0M7REK7	Lactobacillus_phage	5.6e-10	43.4
WP_087741646.1\|708069_708675_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_057732348.1\|708701_709241_+	nucleoside deaminase	NA	NA	NA	NA
WP_087741647.1\|709583_710759_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_087741648.1\|710923_712723_+	beta-glucuronidase	B9U1V4	Vaccinia_virus	1.4e-135	45.6
WP_087741649.1\|713224_715039_+	DNA polymerase III subunit gamma/tau	A0A1U9WR94	Streptococcus_virus	9.6e-60	39.5
WP_172825267.1\|715060_715387_+	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
WP_057800811.1\|715420_716020_+	recombination protein RecR	NA	NA	NA	NA
WP_087741650.1\|716034_716298_+	YaaL family protein	NA	NA	NA	NA
WP_157667846.1\|716474_716750_+	hypothetical protein	NA	NA	NA	NA
WP_087509149.1\|717091_717867_-\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.9e-25	49.5
WP_191982780.1\|718601_719513_+	glycosyl hydrolase family 8	NA	NA	NA	NA
WP_087741653.1\|719530_720811_+	hypothetical protein	NA	NA	NA	NA
WP_172825238.1\|720823_721030_+	hypothetical protein	NA	NA	NA	NA
WP_157667847.1\|721022_722594_+	hypothetical protein	NA	NA	NA	NA
WP_087741656.1\|722626_723880_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_087741657.1\|723818_725975_+	cellulose biosynthesis cyclic di-GMP-binding regulatory protein BcsB	NA	NA	NA	NA
WP_057732329.1\|725967_726825_+	hypothetical protein	NA	NA	NA	NA
WP_087741658.1\|727012_727669_+	dTMP kinase	M1PSC7	Streptococcus_phage	1.3e-51	55.3
WP_057732325.1\|727682_728012_+	cyclic-di-AMP receptor	NA	NA	NA	NA
WP_087741659.1\|728021_729041_+	DNA polymerase III subunit delta'	A0A1U9WR94	Streptococcus_virus	4.4e-09	26.3
WP_057732321.1\|729066_729408_+	DNA replication initiation control protein YabA	NA	NA	NA	NA
WP_087741660.1\|729424_730327_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	6.4e-81	57.7
WP_057732318.1\|730316_731057_+	acyl-ACP thioesterase	NA	NA	NA	NA
WP_057732316.1\|731266_731989_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_057732314.1\|731972_732593_+	ribosomal protein S18-alanine N-acetyltransferase	NA	NA	NA	NA
WP_087741661.1\|732644_733688_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	6.3e-56	39.9
WP_087741662.1\|733765_735718_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	2.4e-56	30.8
WP_057732308.1\|736086_736725_+	redox-sensing transcriptional repressor Rex	NA	NA	NA	NA
WP_057732305.1\|737324_737609_+	co-chaperone GroES	A0A221S2L4	uncultured_virus	5.1e-08	45.9
WP_087741663.1\|737674_739300_+	chaperonin GroEL	A0A240F766	uncultured_virus	3.5e-154	54.4
WP_087741240.1\|739526_740789_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	3.7e-50	33.2
WP_157667836.1\|740886_741720_-\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_087741665.1\|741871_742822_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.7e-20	29.9
WP_087741666.1\|742998_744834_+	APC family permease	NA	NA	NA	NA
WP_015473476.1\|744912_745842_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9

DBSCAN-SWA_8

804790 : 876757

Bacillus_phage(16.67%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087741240.1\|804790_806053_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	3.7e-50	33.2
WP_057731083.1\|806927_807641_+	uracil-DNA glycosylase	V5NWU7	Chelonid_alphaherpesvirus	1.9e-43	44.1
WP_087741699.1\|807688_808666_+	phosphate acetyltransferase	NA	NA	NA	NA
WP_087741700.1\|808858_809335_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_057731078.1\|809327_809861_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_087741701.1\|809886_811584_-\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.3e-103	40.2
WP_057731076.1\|811812_812349_-	3'-5' exonuclease	A0A0A8WJ41	Clostridium_phage	1.6e-07	26.4
WP_057731075.1\|812370_813135_-	exodeoxyribonuclease III	E3T4M6	Cafeteria_roenbergensis_virus	6.1e-56	45.5
WP_057731073.1\|813413_814325_+	UDP-N-acetylmuramate dehydrogenase	NA	NA	NA	NA
WP_057731071.1\|814340_816473_+	sodium:proton antiporter	NA	NA	NA	NA
WP_057731069.1\|816819_817473_-	DUF1361 domain-containing protein	NA	NA	NA	NA
WP_057731068.1\|817760_818609_+	TIGR00159 family protein	NA	NA	NA	NA
WP_087741702.1\|818608_819571_+	cell surface protein	NA	NA	NA	NA
WP_087741703.1\|819609_820968_+	phosphoglucosamine mutase	A0A127AWJ1	Bacillus_phage	4.7e-19	24.6
WP_087741704.1\|821309_823124_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	M1H1Z3	Paramecium_bursaria_Chlorella_virus	1.4e-95	37.0
WP_087741233.1\|823342_823798_+\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	5.1e-18	37.0
WP_087741705.1\|824342_827666_+	SEC10/PgrA surface exclusion domain-containing protein	NA	NA	NA	NA
WP_172825269.1\|828132_828837_+	6-phosphogluconolactonase	NA	NA	NA	NA
WP_087741707.1\|828933_830364_+	glucosaminidase domain-containing protein	Q9ZXE4	Bacillus_phage	3.7e-14	36.7
WP_057732069.1\|830567_831653_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_057732067.1\|832033_832342_+	hypothetical protein	NA	NA	NA	NA
WP_087741708.1\|832468_833824_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_087741709.1\|834891_835536_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_087741710.1\|835592_836153_+	sugar O-acetyltransferase	NA	NA	NA	NA
WP_057732060.1\|836247_837174_-	exopolyphosphatase	NA	NA	NA	NA
WP_057732058.1\|837170_839339_-	RNA degradosome polyphosphate kinase	NA	NA	NA	NA
WP_057732056.1\|839335_840868_-	exopolyphosphatase	NA	NA	NA	NA
WP_087741711.1\|841080_841422_-	LicD family protein	NA	NA	NA	NA
WP_087741887.1\|841505_842522_-\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	1.4e-36	32.8
WP_087741712.1\|843320_843773_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_170218388.1\|843802_843976_+	hypothetical protein	NA	NA	NA	NA
WP_087741713.1\|844020_844479_-	OsmC family protein	NA	NA	NA	NA
WP_087741714.1\|844848_845031_+	hypothetical protein	NA	NA	NA	NA
WP_057732046.1\|845952_846324_-	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_087741715.1\|846535_847030_+	alcohol dehydrogenase	M4SQJ2	Pseudoalteromonas_phage	4.4e-07	43.1
WP_057732043.1\|847183_847558_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_087741716.1\|847645_848671_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	5.7e-41	35.5
WP_087741717.1\|848766_849486_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.7e-13	25.2
WP_087741718.1\|849472_850258_+	hypothetical protein	NA	NA	NA	NA
WP_087741719.1\|850312_850996_-	LysM peptidoglycan-binding domain-containing C40 family peptidase	D2KRB9	Lactobacillus_phage	7.7e-10	38.5
WP_087741720.1\|852018_852942_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_087741721.1\|853052_854312_+	3-isopropylmalate dehydratase large subunit	NA	NA	NA	NA
WP_087741722.1\|854311_854830_+	3-isopropylmalate dehydratase	NA	NA	NA	NA
WP_087741723.1\|854831_856241_+	anion permease	NA	NA	NA	NA
WP_087741724.1\|856384_857248_+	metallophosphoesterase	NA	NA	NA	NA
WP_087741725.1\|857611_858793_+	hypothetical protein	NA	NA	NA	NA
WP_087741726.1\|858795_859065_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_087741727.1\|859143_860109_-	hypothetical protein	NA	NA	NA	NA
WP_057732007.1\|861069_861798_+	response regulator transcription factor	W8CYM9	Bacillus_phage	7.3e-35	36.0
WP_087741728.1\|861800_863267_+	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	2.5e-21	30.5
WP_087741729.1\|863642_864794_+	class I SAM-dependent rRNA methyltransferase	NA	NA	NA	NA
WP_087741730.1\|864976_865846_+	glucose transporter GlcU	NA	NA	NA	NA
WP_057731999.1\|865990_867337_+	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_087741731.1\|867477_868119_+	hypothetical protein	NA	NA	NA	NA
WP_087741732.1\|868143_868764_+	hypothetical protein	NA	NA	NA	NA
WP_087741733.1\|868779_869556_+	hypothetical protein	NA	NA	NA	NA
WP_172825240.1\|869988_873801_+	AAA family ATPase	V5UQM2	Mycobacterium_phage	1.6e-40	37.0
WP_087741735.1\|874338_875733_+	hypothetical protein	NA	NA	NA	NA
WP_087741736.1\|875827_876757_+\|transposase	IS30 family transposase	H7BW61	unidentified_phage	5.0e-20	30.2

DBSCAN-SWA_9

888817 : 939652

Staphylococcus_phage(23.08%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_057731926.1\|888817_889123_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_057731924.1\|889130_890600_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_057731922.1\|890599_892021_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_087741742.1\|892043_893048_+	diacylglycerol kinase	A0A1V0SBJ0	Catovirus	1.1e-15	27.1
WP_087741743.1\|893142_894513_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	1.5e-129	51.9
WP_087741744.1\|894749_894941_+	histidine kinase	NA	NA	NA	NA
WP_010620880.1\|895021_896047_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	2.3e-42	36.1
WP_087741745.1\|896174_897104_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	1.9e-19	33.5
WP_087741746.1\|897791_898838_-	NADPH dehydrogenase	NA	NA	NA	NA
WP_087741747.1\|898987_899356_+	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
WP_031263932.1\|899535_900273_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	2.5e-59	50.4
WP_087741748.1\|900282_901503_-\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	1.2e-103	49.1
WP_087741749.1\|902299_903622_+	S-layer protein	NA	NA	NA	NA
WP_087741750.1\|903960_904830_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_087741751.1\|904947_905814_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	2.1e-52	42.4
WP_087741752.1\|905831_906695_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	8.7e-51	38.2
WP_057731898.1\|907049_907739_+	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_057731896.1\|907772_908960_+	phosphopentomutase	NA	NA	NA	NA
WP_057731894.1\|908985_909690_+	purine-nucleoside phosphorylase	NA	NA	NA	NA
WP_057731892.1\|909752_910703_+	sugar-binding transcriptional regulator	NA	NA	NA	NA
WP_087741753.1\|910815_912114_+	pyrimidine-nucleoside phosphorylase	A0A0H3UZD4	Geobacillus_virus	3.3e-118	51.1
WP_057731888.1\|912669_914097_+	gamma-glutamylcysteine synthetase	NA	NA	NA	NA
WP_087741754.1\|914115_914997_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_087741755.1\|915144_915684_+	flavodoxin	NA	NA	NA	NA
WP_087741756.1\|915687_916431_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_087741757.1\|916450_916867_+	cupin domain-containing protein	NA	NA	NA	NA
WP_087741758.1\|916868_917186_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_172825241.1\|917260_918160_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_087741760.1\|918278_919766_+	FAD-binding protein	NA	NA	NA	NA
WP_172825270.1\|919839_921165_-	amino acid permease	NA	NA	NA	NA
WP_087741762.1\|921240_923013_-\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.4e-103	40.2
WP_057731873.1\|923200_924559_-	gluconate permease	NA	NA	NA	NA
WP_087741763.1\|924730_926284_-	gluconokinase	NA	NA	NA	NA
WP_057731869.1\|926594_927464_+	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_087741764.1\|927516_928284_+	Lyzozyme M1 (1,4-beta-N-acetylmuramidase)	NA	NA	NA	NA
WP_057731865.1\|928382_928763_-	DUF4828 domain-containing protein	NA	NA	NA	NA
WP_087741765.1\|928984_929986_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_087741766.1\|930004_931381_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	2.5e-36	28.8
WP_157667852.1\|931882_932098_+	hypothetical protein	NA	NA	NA	NA
WP_087741768.1\|932185_933115_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	3.8e-20	29.9
WP_087741769.1\|933146_933662_+	DUF2335 domain-containing protein	NA	NA	NA	NA
WP_157667836.1\|934061_934895_+\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_057731859.1\|934997_935339_+	hypothetical protein	NA	NA	NA	NA
WP_087741770.1\|935765_937778_+	transketolase	NA	NA	NA	NA
WP_015473476.1\|938722_939652_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9

DBSCAN-SWA_10

970629 : 1016533

Streptococcus_phage(16.67%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087741788.1\|970629_972846_-\|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	1.1e-126	40.3
WP_057731802.1\|973134_973332_+	hypothetical protein	NA	NA	NA	NA
WP_057731799.1\|973941_974208_+	phosphocarrier protein HPr	NA	NA	NA	NA
WP_087741789.1\|974207_975938_+	phosphoenolpyruvate--protein phosphotransferase	NA	NA	NA	NA
WP_087741790.1\|976118_977297_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_087741791.1\|977309_978332_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_057731791.1\|978336_979371_+	flippase-like domain-containing protein	NA	NA	NA	NA
WP_057731789.1\|979446_979683_+	YkuJ family protein	NA	NA	NA	NA
WP_057731786.1\|979820_981884_+	LTA synthase family protein	W6LM83	Streptococcus_phage	2.6e-154	46.7
WP_087741240.1\|983591_984854_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	3.7e-50	33.2
WP_087741793.1\|985384_985708_-	heavy metal-binding domain-containing protein	M4STD1	Rhodobacter_phage	4.6e-05	34.6
WP_157667853.1\|986122_986608_+	hypothetical protein	NA	NA	NA	NA
WP_087741795.1\|986655_987003_-	hypothetical protein	NA	NA	NA	NA
WP_087741796.1\|987135_987843_-	hypothetical protein	NA	NA	NA	NA
WP_057734414.1\|988090_989278_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.2e-154	71.0
WP_057734416.1\|989746_991375_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_087741797.1\|991398_992754_+	M20/M25/M40 family metallo-hydrolase	NA	NA	NA	NA
WP_087742779.1\|992948_994430_+	MFS transporter	NA	NA	NA	NA
WP_057734418.1\|994503_994830_+	DUF960 domain-containing protein	NA	NA	NA	NA
WP_057734421.1\|994923_995565_-	deoxynucleoside kinase	C1KFI3	Lactobacillus_virus	9.0e-45	45.5
WP_087741798.1\|995722_996493_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_057730258.1\|996567_997239_-	beta-phosphoglucomutase	NA	NA	NA	NA
WP_087741799.1\|997259_999977_-	glycoside hydrolase family 65 protein	NA	NA	NA	NA
WP_087741800.1\|1000318_1000570_+	hypothetical protein	NA	NA	NA	NA
WP_015473476.1\|1000856_1001786_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_087741802.1\|1001835_1002522_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_057730265.1\|1002603_1003083_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_087741803.1\|1004062_1004572_+	VanZ family protein	NA	NA	NA	NA
WP_057730269.1\|1004678_1004966_+	heavy metal-binding domain-containing protein	NA	NA	NA	NA
WP_087741804.1\|1005227_1005689_-	hypothetical protein	NA	NA	NA	NA
WP_087741805.1\|1006053_1006251_+	type II toxin-antitoxin system HicA family toxin	D6PSW1	Lactobacillus_phage	8.3e-26	87.7
WP_087741806.1\|1006353_1006737_+	type II toxin-antitoxin system HicB family antitoxin	D6PSW2	Lactobacillus_phage	5.1e-19	81.8
WP_087509149.1\|1007265_1008041_-\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.9e-25	49.5
WP_087741809.1\|1008766_1009099_-	hypothetical protein	NA	NA	NA	NA
WP_057730272.1\|1009300_1010629_-	amino acid permease	NA	NA	NA	NA
WP_087741810.1\|1010997_1013514_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	7.9e-137	32.1
WP_012695418.1\|1013761_1014787_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	5.7e-41	35.5
WP_087741811.1\|1014999_1015209_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_157667836.1\|1015378_1016212_+\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_082605156.1\|1016320_1016533_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_11

1042587 : 1103826

Streptococcus_phage(21.43%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087741823.1\|1042587_1043235_+\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_087741824.1\|1043337_1044408_+	competence protein	NA	NA	NA	NA
WP_087741825.1\|1044488_1046300_+	oligoendopeptidase F	NA	NA	NA	NA
WP_087741826.1\|1046357_1047218_-	DegV family protein	NA	NA	NA	NA
WP_057730131.1\|1047346_1047991_-	DsbA family protein	NA	NA	NA	NA
WP_057730129.1\|1048315_1048969_+	GTP pyrophosphokinase family protein	NA	NA	NA	NA
WP_057730127.1\|1048971_1049775_+	NAD kinase	NA	NA	NA	NA
WP_087741827.1\|1049771_1050671_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_087741828.1\|1051378_1052308_-\|transposase	IS30 family transposase	H7BW61	unidentified_phage	1.2e-18	29.5
WP_087741830.1\|1052453_1053911_+	accessory Sec system glycosyltransferase Asp1	NA	NA	NA	NA
WP_087741831.1\|1053924_1055478_+	glycosyltransferase	NA	NA	NA	NA
WP_057730116.1\|1055512_1055908_+	hypothetical protein	A0A2K9L0P7	Tupanvirus	2.3e-14	35.3
WP_087741832.1\|1055904_1057551_+	hypothetical protein	E5E464	Acinetobacter_phage	8.0e-05	29.6
WP_087741833.1\|1057553_1058279_+	NTP transferase domain-containing protein	M1H491	Acanthocystis_turfacea_Chlorella_virus	1.2e-26	32.3
WP_087741834.1\|1058428_1060216_+	CapA family protein	NA	NA	NA	NA
WP_157667854.1\|1060231_1062112_+	hypothetical protein	NA	NA	NA	NA
WP_057732297.1\|1063109_1063733_-	copper resistance protein	NA	NA	NA	NA
WP_087742783.1\|1063953_1064817_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_057732295.1\|1065068_1065581_+\|tRNA	tRNA (cytidine(34)-2'-O)-methyltransferase	NA	NA	NA	NA
WP_087741836.1\|1065609_1067964_+	cell division protein FtsK	A0A218M9A2	Mycobacterium_phage	6.6e-85	49.3
WP_087741837.1\|1068170_1068776_+\|transposase	transposase family protein	A0A1S5SBP9	Streptococcus_phage	2.2e-21	34.7
WP_087741838.1\|1068785_1069715_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_083484143.1\|1069902_1070022_-	DUF4044 domain-containing protein	NA	NA	NA	NA
WP_057732291.1\|1070192_1070546_+	DUF3397 family protein	NA	NA	NA	NA
WP_057732289.1\|1070747_1071179_+	division/cell wall cluster transcriptional repressor MraZ	NA	NA	NA	NA
WP_057732286.1\|1071206_1072148_+	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	NA	NA	NA	NA
WP_087741840.1\|1072198_1072600_+	cell division protein FtsL	NA	NA	NA	NA
WP_087741841.1\|1072599_1074756_+	penicillin-binding protein	NA	NA	NA	NA
WP_087741842.1\|1074778_1075750_+	phospho-N-acetylmuramoyl-pentapeptide- transferase	NA	NA	NA	NA
WP_087741843.1\|1075954_1077334_+	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	NA	NA	NA	NA
WP_057732275.1\|1077334_1078429_+	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase	NA	NA	NA	NA
WP_087741844.1\|1078462_1079326_+	FtsQ-type POTRA domain-containing protein	NA	NA	NA	NA
WP_087741845.1\|1079392_1080418_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	5.7e-41	35.5
WP_087741846.1\|1080685_1082023_+	cell division protein FtsA	NA	NA	NA	NA
WP_087741847.1\|1082044_1083325_+	cell division protein FtsZ	NA	NA	NA	NA
WP_087741848.1\|1083362_1083806_+	cell division protein SepF	NA	NA	NA	NA
WP_083485253.1\|1083853_1084126_+	YggT family protein	NA	NA	NA	NA
WP_087741849.1\|1084149_1084929_+	RNA-binding protein	NA	NA	NA	NA
WP_087741850.1\|1084948_1085656_+	DivIVA domain-containing protein	NA	NA	NA	NA
WP_087741851.1\|1086010_1088821_+\|tRNA	isoleucine--tRNA ligase	A0A2P1ELB8	Moumouvirus	8.4e-87	27.4
WP_057730548.1\|1088978_1089200_+	cold shock domain-containing protein	NA	NA	NA	NA
WP_057730550.1\|1089203_1089746_+	NUDIX hydrolase	NA	NA	NA	NA
WP_057730552.1\|1089754_1090069_+	hypothetical protein	NA	NA	NA	NA
WP_087741852.1\|1090086_1090779_+	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_087741853.1\|1090804_1091971_+	cysteine desulfurase	A0A1X7QGF3	Faustovirus	3.0e-30	30.1
WP_057730557.1\|1091972_1092314_+	DUF1831 domain-containing protein	NA	NA	NA	NA
WP_087741854.1\|1092388_1093246_+	metallophosphoesterase family protein	NA	NA	NA	NA
WP_087741855.1\|1093381_1094512_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_087741240.1\|1094745_1096008_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	3.7e-50	33.2
WP_087741856.1\|1096201_1096858_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_087741857.1\|1096871_1097555_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_087741858.1\|1097561_1100075_+	ATP-dependent RecD-like DNA helicase	A0A0K2FLP8	Brevibacillus_phage	3.6e-57	26.7
WP_087741859.1\|1100165_1101152_+	ribose-phosphate diphosphokinase	A0A1V0SHF7	Hokovirus	4.3e-38	34.0
WP_087741860.1\|1101218_1102274_+	acyltransferase	NA	NA	NA	NA
WP_087741240.1\|1102563_1103826_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	3.7e-50	33.2

DBSCAN-SWA_12

1112501 : 1172408

Staphylococcus_virus(10.53%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087741865.1\|1112501_1114196_+\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.3e-103	40.2
WP_087741866.1\|1114250_1115141_+	C40 family peptidase	A0A0A8WIF2	Clostridium_phage	1.6e-15	41.4
WP_087741867.1\|1115244_1116285_+	DUF1002 domain-containing protein	NA	NA	NA	NA
WP_087741233.1\|1116494_1116950_+\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	5.1e-18	37.0
WP_087741868.1\|1117537_1119211_+	LysM peptidoglycan-binding domain-containing protein	D2KRB9	Lactobacillus_phage	4.8e-13	45.7
WP_057730586.1\|1119389_1119596_+	hypothetical protein	NA	NA	NA	NA
WP_087742784.1\|1119659_1120619_-	diacylglycerol kinase family lipid kinase	NA	NA	NA	NA
WP_087742785.1\|1120749_1121766_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	7.1e-36	33.4
WP_087741869.1\|1121965_1123645_-	ribonuclease J	NA	NA	NA	NA
WP_057730590.1\|1123641_1123860_-	DNA-dependent RNA polymerase auxiliary subunit epsilon family protein	NA	NA	NA	NA
WP_057730592.1\|1124060_1124558_+	hypothetical protein	NA	NA	NA	NA
WP_057730594.1\|1124652_1125213_-	peptide deformylase	A0A2I7S809	Vibrio_phage	7.4e-11	41.2
WP_057730596.1\|1125490_1126606_+	pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha	NA	NA	NA	NA
WP_057730597.1\|1126608_1127586_+	alpha-ketoacid dehydrogenase subunit beta	NA	NA	NA	NA
WP_087741870.1\|1127663_1128980_+	2-oxo acid dehydrogenase subunit E2	NA	NA	NA	NA
WP_057730601.1\|1128987_1130415_+	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	3.4e-44	27.3
WP_087741871.1\|1130583_1131489_+	lactate dehydrogenase	NA	NA	NA	NA
WP_087741872.1\|1131489_1131789_+	UPF0223 family protein	NA	NA	NA	NA
WP_057730607.1\|1131788_1132580_+	inositol monophosphatase family protein	NA	NA	NA	NA
WP_057730611.1\|1132716_1134561_+	translational GTPase TypA	NA	NA	NA	NA
WP_087741873.1\|1134983_1136138_+	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_057730614.1\|1136159_1136444_+	YlbG family protein	NA	NA	NA	NA
WP_057730615.1\|1136440_1136998_+	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	NA	NA	NA	NA
WP_087741874.1\|1137000_1137489_+	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	5.4e-26	41.5
WP_087741875.1\|1137485_1138547_+	PDZ domain-containing protein	NA	NA	NA	NA
WP_087741468.1\|1138605_1139604_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.5e-51	38.1
WP_087741876.1\|1139773_1140493_+	helix-hairpin-helix domain-containing protein	NA	NA	NA	NA
WP_087741877.1\|1140540_1141023_+	ComE operon protein 2	A7KUY9	Bacillus_phage	5.4e-34	55.8
WP_087742786.1\|1141073_1143278_+	DNA internalization-related competence protein ComEC/Rec2	Q332C0	Clostridium_botulinum_C_phage	2.2e-26	31.7
WP_087741878.1\|1143280_1144315_+	DNA polymerase III subunit delta	NA	NA	NA	NA
WP_045807966.1\|1144393_1144648_-	30S ribosomal protein S20	NA	NA	NA	NA
WP_057730626.1\|1144925_1145195_+	30S ribosomal protein S15	NA	NA	NA	NA
WP_087741879.1\|1145403_1147269_+	ribonuclease J	NA	NA	NA	NA
WP_087741880.1\|1147335_1148265_+	hypothetical protein	NA	NA	NA	NA
WP_057730629.1\|1148438_1149629_+	elongation factor Tu	A0A1V0SGC3	Hokovirus	4.7e-31	29.5
WP_172825242.1\|1149958_1151191_+	argininosuccinate synthase	NA	NA	NA	NA
WP_087741881.1\|1151187_1152591_+	argininosuccinate lyase	NA	NA	NA	NA
WP_087741882.1\|1152887_1154195_+	trigger factor	NA	NA	NA	NA
WP_087741883.1\|1154415_1155666_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	3.0e-137	59.1
WP_057730637.1\|1155870_1156464_+	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_057730639.1\|1156466_1156766_+	nucleoside triphosphate pyrophosphohydrolase family protein	A0A1S7FYY8	Listeria_phage	3.1e-24	49.5
WP_057730641.1\|1156825_1157008_-	hypothetical protein	NA	NA	NA	NA
WP_057730643.1\|1157164_1158982_+	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_087741884.1\|1159068_1160361_+	GTPase ObgE	NA	NA	NA	NA
WP_087741885.1\|1160419_1161187_-	hypothetical protein	NA	NA	NA	NA
WP_057730648.1\|1161200_1161473_-	hypothetical protein	NA	NA	NA	NA
WP_057730650.1\|1161633_1162584_+	ribonuclease Z	NA	NA	NA	NA
WP_057730652.1\|1162580_1162967_+	DUF1049 domain-containing protein	NA	NA	NA	NA
WP_087741886.1\|1163035_1165357_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.3e-69	30.1
WP_057730657.1\|1165373_1165892_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	1.7e-25	42.8
WP_057730659.1\|1167472_1168549_+	YdcF family protein	NA	NA	NA	NA
WP_057730661.1\|1168874_1169273_-	TIR domain-containing protein	A0A1J0MFJ5	Staphylococcus_phage	1.9e-08	26.6
WP_087741887.1\|1169539_1170556_+\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	1.4e-36	32.8
WP_087741888.1\|1170710_1172408_-\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.3e-103	40.2

DBSCAN-SWA_13

1271211 : 1337056

Bacillus_virus(12.5%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087741946.1\|1271211_1271919_+\|tRNA	tRNA (adenine(22)-N(1))-methyltransferase TrmK	NA	NA	NA	NA
WP_087741947.1\|1271905_1272712_+	Nif3-like dinuclear metal center hexameric protein	NA	NA	NA	NA
WP_057730835.1\|1272767_1274009_+	peptidase T	NA	NA	NA	NA
WP_087741948.1\|1274148_1276758_+	ATP-dependent chaperone ClpB	A0A2I7SAX5	Vibrio_phage	1.6e-124	34.1
WP_087741949.1\|1276900_1280242_+	DNA polymerase III subunit alpha	A0A291AWR1	Streptomyces_phage	7.5e-143	32.5
WP_087741950.1\|1280335_1281052_+	transaldolase	A0A127KMN5	Cyanophage	2.6e-16	29.2
WP_087741951.1\|1281314_1283072_+	pyruvate kinase	NA	NA	NA	NA
WP_057730842.1\|1283256_1284147_+	DNA-binding protein	NA	NA	NA	NA
WP_087741952.1\|1284166_1285063_+	site-specific tyrosine recombinase XerD	A0A0K2CP59	Brevibacillus_phage	3.7e-36	30.7
WP_057731045.1\|1285120_1285516_+	hypothetical protein	NA	NA	NA	NA
WP_087741953.1\|1285469_1286249_+	segregation/condensation protein A	NA	NA	NA	NA
WP_057730847.1\|1286226_1286841_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	3.9e-13	45.0
WP_057730849.1\|1286816_1287542_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_087741954.1\|1288662_1289727_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_087741955.1\|1289704_1291135_+	ATP-dependent DNA helicase RecQ	F2NZ48	Diadromus_pulchellus_ascovirus	2.1e-49	36.1
WP_087741956.1\|1291549_1292170_+	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_087741957.1\|1292208_1292913_+	(d)CMP kinase	NA	NA	NA	NA
WP_087741887.1\|1292942_1293959_-\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	1.4e-36	32.8
WP_087741958.1\|1294159_1295473_+	30S ribosomal protein S1	NA	NA	NA	NA
WP_057730857.1\|1295590_1296898_+	ribosome biogenesis GTPase Der	NA	NA	NA	NA
WP_011667553.1\|1297138_1297414_+	HU family DNA-binding protein	A0A0H3UZA0	Geobacillus_virus	3.1e-26	68.5
WP_087741959.1\|1297525_1298788_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_087741960.1\|1298956_1299850_-	YitT family protein	M1Q1P6	Streptococcus_phage	9.6e-53	40.1
WP_087741961.1\|1300086_1301295_+\|tRNA	CCA tRNA nucleotidyltransferase	G3MAR3	Bacillus_virus	3.0e-33	41.5
WP_057730863.1\|1301315_1303211_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	1.2e-47	29.0
WP_087741962.1\|1303226_1304177_+	thymidylate synthase	A0A0N9SH48	Staphylococcus_phage	5.0e-116	61.8
WP_087741963.1\|1304188_1304680_+	dihydrofolate reductase	M4M9C1	Vibrio_phage	1.5e-12	32.7
WP_057730868.1\|1304726_1305368_-	hemolysin III family protein	NA	NA	NA	NA
WP_057730870.1\|1305507_1306359_+	DegV family protein	A0A0N9SI50	Staphylococcus_phage	1.3e-14	32.8
WP_087742792.1\|1306440_1307358_+	lysophospholipase	NA	NA	NA	NA
WP_057730871.1\|1307373_1307994_+	YpmS family protein	NA	NA	NA	NA
WP_057730873.1\|1308004_1308226_+	YozE family protein	NA	NA	NA	NA
WP_087741539.1\|1308820_1309846_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	3.9e-42	36.1
WP_157667855.1\|1309891_1311802_+	SEC10/PgrA surface exclusion domain-containing protein	NA	NA	NA	NA
WP_087741965.1\|1311753_1312572_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_157667856.1\|1312762_1313347_+	zinc-ribbon domain-containing protein	NA	NA	NA	NA
WP_087741968.1\|1313391_1313907_+	zinc ribbon domain-containing protein	NA	NA	NA	NA
WP_087741969.1\|1313934_1314990_+	hypothetical protein	NA	NA	NA	NA
WP_087741887.1\|1315115_1316132_-\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	1.4e-36	32.8
WP_087741970.1\|1316625_1317504_+	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_087741971.1\|1317496_1318297_+	ribonuclease HII	G4YAY0	Emiliania_huxleyi_virus	4.2e-23	37.2
WP_087741972.1\|1318339_1319233_+	DNA-protecting protein DprA	NA	NA	NA	NA
WP_087741973.1\|1319367_1321479_+	type I DNA topoisomerase	A0A1V0SCS0	Indivirus	6.1e-98	35.0
WP_087741974.1\|1321584_1322520_+	tyrosine recombinase XerC	A0A1I9SC88	Mycobacterium_phage	6.4e-15	27.7
WP_057730879.1\|1322541_1323084_+	HslU--HslV peptidase proteolytic subunit	NA	NA	NA	NA
WP_057730882.1\|1323101_1324517_+\|protease	ATP-dependent protease ATPase subunit HslU	A0A1B2IFI0	Erwinia_phage	2.8e-30	26.0
WP_087741975.1\|1324602_1325478_+	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_057730885.1\|1325527_1326154_-	glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_087741976.1\|1326413_1328384_+	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	7.6e-119	42.7
WP_087741977.1\|1328404_1330855_+	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	2.7e-97	31.7
WP_087741402.1\|1330889_1331819_-\|transposase	IS30 family transposase	H7BW61	unidentified_phage	1.1e-19	29.5
WP_087741979.1\|1332039_1332999_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_087741980.1\|1333037_1333973_+	manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
WP_057730893.1\|1334142_1334400_+	hypothetical protein	NA	NA	NA	NA
WP_087741981.1\|1334454_1335342_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_087741982.1\|1335468_1335846_-	hypothetical protein	NA	NA	NA	NA
WP_015473476.1\|1336126_1337056_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9

DBSCAN-SWA_14

1342550 : 1384161

Staphylococcus_phage(22.22%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_074030222.1\|1342550_1343471_+\|transposase	IS30-like element ISLsa1 family transposase	Q9MBM9	Staphylococcus_prophage	1.6e-50	38.2
WP_157667858.1\|1343400_1343934_-	hypothetical protein	NA	NA	NA	NA
WP_012695418.1\|1344131_1345157_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	5.7e-41	35.5
WP_087741990.1\|1345490_1346726_+	MFS transporter	NA	NA	NA	NA
WP_087741991.1\|1346756_1347974_+	MFS transporter	NA	NA	NA	NA
WP_087741992.1\|1348024_1348693_-	chloramphenicol acetyltransferase	NA	NA	NA	NA
WP_087741993.1\|1349080_1349809_-	DUF2087 domain-containing protein	NA	NA	NA	NA
WP_057730922.1\|1350029_1350608_+\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_087741994.1\|1350735_1351209_+	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_087741995.1\|1351201_1351729_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_087741996.1\|1351765_1352215_+	NUDIX domain-containing protein	D0R7J3	Paenibacillus_phage	7.5e-22	38.3
WP_015473476.1\|1353659_1354589_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_157667859.1\|1354705_1356001_-	hypothetical protein	NA	NA	NA	NA
WP_087741998.1\|1356133_1357150_-\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	1.4e-36	32.8
WP_015473476.1\|1357339_1358269_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_011101435.1\|1358404_1358842_-	GAF domain-containing protein	NA	NA	NA	NA
WP_087741999.1\|1358934_1359195_-	hypothetical protein	NA	NA	NA	NA
WP_087742000.1\|1359184_1359754_-	molybdenum cofactor guanylyltransferase	NA	NA	NA	NA
WP_087742001.1\|1359770_1360262_-	cyclic pyranopterin monophosphate synthase MoaC	NA	NA	NA	NA
WP_087742002.1\|1360254_1360752_-	molybdopterin-guanine dinucleotide biosynthesis protein B	NA	NA	NA	NA
WP_063852938.1\|1360730_1361945_-	molybdopterin molybdotransferase MoeA	NA	NA	NA	NA
WP_063852937.1\|1361965_1362433_-	MogA/MoaB family molybdenum cofactor biosynthesis protein	NA	NA	NA	NA
WP_087742003.1\|1362429_1363464_-	HesA/MoeB/ThiF family protein	NA	NA	NA	NA
WP_087742004.1\|1363701_1367373_+	nitrate reductase subunit alpha	NA	NA	NA	NA
WP_087742005.1\|1367362_1368922_+	nitrate reductase subunit beta	A0A077SL61	Escherichia_phage	7.8e-18	45.1
WP_087742006.1\|1368914_1369487_+	nitrate reductase molybdenum cofactor assembly chaperone	NA	NA	NA	NA
WP_021356451.1\|1369483_1370173_+	respiratory nitrate reductase subunit gamma	NA	NA	NA	NA
WP_087742007.1\|1370272_1370755_+\|transposase	transposase	NA	NA	NA	NA
WP_157667901.1\|1370727_1371621_+\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.7e-33	42.7
WP_087742008.1\|1371712_1372567_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.4e-53	41.7
WP_087742009.1\|1372584_1373187_-	NAD(P)H-binding protein	NA	NA	NA	NA
WP_087742010.1\|1373188_1373632_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_087742011.1\|1373752_1375207_-	MFS transporter	NA	NA	NA	NA
WP_087742012.1\|1375220_1375598_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_087742013.1\|1375778_1376363_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_087742014.1\|1376588_1376855_+	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_087742015.1\|1376856_1377114_+	Txe/YoeB family addiction module toxin	NA	NA	NA	NA
WP_087742016.1\|1377226_1378054_-	NmrA family NAD(P)-binding protein	NA	NA	NA	NA
WP_087742017.1\|1378185_1378743_+	TetR/AcrR family transcriptional regulator C-terminal domain-containing protein	NA	NA	NA	NA
WP_087742018.1\|1378814_1379345_-	serine hydrolase	NA	NA	NA	NA
WP_087742019.1\|1379344_1380226_-	hypothetical protein	NA	NA	NA	NA
WP_087742020.1\|1380630_1382820_-	RNA-binding transcriptional accessory protein	NA	NA	NA	NA
WP_087742793.1\|1383076_1383295_-	Txe/YoeB family addiction module toxin	NA	NA	NA	NA
WP_087742021.1\|1383705_1384161_+\|tRNA	prolyl-tRNA editing protein	NA	NA	NA	NA

DBSCAN-SWA_15

1394937 : 1439713

unidentified_phage(50.0%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015473476.1\|1394937_1395867_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_087742034.1\|1395990_1396416_+	hypothetical protein	NA	NA	NA	NA
WP_087742035.1\|1396551_1397289_-	ATP-binding protein	NA	NA	NA	NA
WP_087742036.1\|1397434_1397689_-	hypothetical protein	NA	NA	NA	NA
WP_087742037.1\|1397810_1399091_-	homoserine dehydrogenase	NA	NA	NA	NA
WP_087742038.1\|1399107_1400394_-	O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase	A0A0B5JD48	Pandoravirus	1.0e-07	23.7
WP_087742039.1\|1400396_1401266_-	homoserine O-succinyltransferase	NA	NA	NA	NA
WP_087742040.1\|1401835_1402702_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_087742041.1\|1402845_1403652_-	aldo/keto reductase	NA	NA	NA	NA
WP_087742795.1\|1403673_1404525_-	sugar transporter	NA	NA	NA	NA
WP_087742042.1\|1404786_1405569_+	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_087742043.1\|1405561_1406176_+	NUDIX hydrolase N-terminal domain-containing protein	NA	NA	NA	NA
WP_087742044.1\|1406381_1406903_+	VanZ family protein	NA	NA	NA	NA
WP_087742045.1\|1407031_1408084_+	AI-2E family transporter	NA	NA	NA	NA
WP_057731024.1\|1408155_1408587_-	GtrA family protein	NA	NA	NA	NA
WP_080487858.1\|1408780_1409568_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_057731025.1\|1409799_1410339_-	folate family ECF transporter S component	NA	NA	NA	NA
WP_157667862.1\|1410768_1411080_+	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_087742047.1\|1411605_1411998_-	hypothetical protein	NA	NA	NA	NA
WP_087509149.1\|1412117_1412893_-\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.9e-25	49.5
WP_087742048.1\|1412958_1413345_-	hypothetical protein	NA	NA	NA	NA
WP_172825247.1\|1413535_1413709_+	hypothetical protein	NA	NA	NA	NA
WP_057730015.1\|1413705_1414572_-	DegV family protein	A0A0N9SI50	Staphylococcus_phage	1.7e-17	44.7
WP_015473476.1\|1415061_1415991_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_087742050.1\|1416914_1418183_-	alkaline phosphatase family protein	NA	NA	NA	NA
WP_057730021.1\|1418232_1418664_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_087742051.1\|1418957_1420676_+	fibronectin/fibrinogen-binding protein	M1IFC6	Paramecium_bursaria_Chlorella_virus	1.7e-05	37.0
WP_057730024.1\|1420743_1423317_-	carbamoyl phosphate synthase	NA	NA	NA	NA
WP_057730027.1\|1423319_1424393_-	carbamoyl phosphate synthase small subunit	NA	NA	NA	NA
WP_057730029.1\|1424424_1424958_-	bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR	NA	NA	NA	NA
WP_087742052.1\|1425090_1426014_-	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_087742053.1\|1426016_1426484_-	signal peptidase II	NA	NA	NA	NA
WP_087742054.1\|1426847_1427489_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_087742055.1\|1427560_1428844_-	amino acid permease	NA	NA	NA	NA
WP_087742056.1\|1428923_1429745_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_087742057.1\|1429842_1430772_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_087742058.1\|1430813_1431710_-\|transposase	IS30 family transposase	H7BW61	unidentified_phage	1.3e-17	31.0
WP_087742060.1\|1432014_1433370_+	adenylosuccinate lyase	NA	NA	NA	NA
WP_087742061.1\|1433434_1435099_-	formate--tetrahydrofolate ligase	NA	NA	NA	NA
WP_057730047.1\|1435098_1435518_-	hypothetical protein	NA	NA	NA	NA
WP_057730049.1\|1435552_1435960_+	ribonuclease HI family protein	NA	NA	NA	NA
WP_087742062.1\|1435935_1437060_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_057730052.1\|1437347_1437560_+	hypothetical protein	NA	NA	NA	NA
WP_087742063.1\|1437628_1438231_-	nitroreductase family protein	NA	NA	NA	NA
WP_087742064.1\|1438334_1438859_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_087742065.1\|1439047_1439713_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_16

1525647 : 1572525

Staphylococcus_virus(18.18%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087742115.1\|1525647_1527342_-\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.3e-103	40.2
WP_087742116.1\|1527514_1528186_-	thiamine diphosphokinase	NA	NA	NA	NA
WP_057734306.1\|1528185_1528839_-	ribulose-phosphate 3-epimerase	NA	NA	NA	NA
WP_087742117.1\|1528851_1529745_-	ribosome small subunit-dependent GTPase A	NA	NA	NA	NA
WP_087742118.1\|1529822_1531871_-	Stk1 family PASTA domain-containing Ser/Thr kinase	A0A1V0SDC3	Indivirus	1.1e-22	33.1
WP_087742119.1\|1531870_1532614_-	Stp1/IreP family PP2C-type Ser/Thr phosphatase	NA	NA	NA	NA
WP_087742120.1\|1532626_1533967_-	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	NA	NA	NA	NA
WP_057734296.1\|1533966_1534911_-\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	4.3e-11	32.7
WP_087742121.1\|1534941_1537350_-	primosomal protein N'	NA	NA	NA	NA
WP_087742122.1\|1537360_1538578_-	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	8.2e-39	33.5
WP_020089007.1\|1538650_1538866_-	DNA-directed RNA polymerase subunit omega	NA	NA	NA	NA
WP_057734291.1\|1538869_1539484_-	guanylate kinase	K4JYM5	Abalone_herpesvirus	1.6e-22	33.9
WP_087742123.1\|1539705_1540035_+	hypothetical protein	NA	NA	NA	NA
WP_087742124.1\|1540113_1542135_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_087742125.1\|1542295_1544005_-	DNA repair protein RecN	NA	NA	NA	NA
WP_057734284.1\|1544082_1544538_-	ArgR family transcriptional regulator	NA	NA	NA	NA
WP_057734282.1\|1544631_1545447_-	TlyA family RNA methyltransferase	NA	NA	NA	NA
WP_087742126.1\|1545443_1546355_-	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_057734278.1\|1546344_1546590_-	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_087742127.1\|1546582_1547935_-	exodeoxyribonuclease VII large subunit	A0A160DEV2	Gordonia_phage	3.6e-27	32.0
WP_087742128.1\|1547921_1548788_-	hypothetical protein	A0A249XZQ2	Enterococcus_phage	5.0e-30	38.0
WP_057734272.1\|1549105_1549552_-	transcription antitermination factor NusB	NA	NA	NA	NA
WP_057734269.1\|1549548_1549989_-	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_057734267.1\|1550037_1550598_-	elongation factor P	NA	NA	NA	NA
WP_087742129.1\|1550675_1551740_-	aminopeptidase P family protein	NA	NA	NA	NA
WP_172757596.1\|1551835_1552132_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_057734263.1\|1552154_1552493_-\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_057734261.1\|1552523_1552832_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_087742130.1\|1553096_1553639_-	dUTP diphosphatase	A0A1L2JY27	Aeribacillus_phage	2.3e-09	31.7
WP_057734257.1\|1553650_1554592_-	hypothetical protein	NA	NA	NA	NA
WP_057734255.1\|1554584_1555463_-	hypothetical protein	NA	NA	NA	NA
WP_057734253.1\|1555685_1557026_-	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_057734251.1\|1557070_1557457_-	MerR family transcriptional regulator	Q9EYF2	Enterobacteria_phage	9.3e-05	34.2
WP_087742131.1\|1557578_1558496_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_057734247.1\|1558677_1558857_+	DUF3042 family protein	NA	NA	NA	NA
WP_087741240.1\|1559060_1560323_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	3.7e-50	33.2
WP_057734245.1\|1560370_1560805_-	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_172825273.1\|1560812_1561787_-	ROK family glucokinase	NA	NA	NA	NA
WP_087742132.1\|1561788_1562019_-	YqgQ family protein	NA	NA	NA	NA
WP_172825274.1\|1562062_1562671_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_087742134.1\|1562759_1563299_-	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_081721478.1\|1563515_1563665_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_057734236.1\|1563791_1565903_-	penicillin-binding protein 2	NA	NA	NA	NA
WP_087742135.1\|1566369_1569003_+	YfhO family protein	NA	NA	NA	NA
WP_087742136.1\|1569197_1571000_+\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.4e-103	40.2
WP_087742137.1\|1571310_1572525_-\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_17

1599666 : 1658611

Staphylococcus_phage(21.43%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087742150.1\|1599666_1601655_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	3.6e-100	33.8
WP_087742151.1\|1601998_1602925_-	primosomal protein DnaI	S5MU12	Brevibacillus_phage	1.4e-25	35.9
WP_087742152.1\|1602924_1604313_-	DnaD domain protein	NA	NA	NA	NA
WP_057734176.1\|1604316_1604823_-	transcriptional repressor NrdR	NA	NA	NA	NA
WP_087742153.1\|1604858_1605458_-	dephospho-CoA kinase	NA	NA	NA	NA
WP_087742154.1\|1605450_1606311_-	bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase	G3MA33	Bacillus_virus	3.9e-27	33.6
WP_087742155.1\|1606330_1608988_-	DNA polymerase I	A0A2H4J6W7	uncultured_Caudovirales_phage	1.6e-50	27.9
WP_057734167.1\|1609148_1609844_-	Bax inhibitor-1/YccA family protein	NA	NA	NA	NA
WP_057734165.1\|1610135_1611467_-	UDP-N-acetylmuramate--L-alanine ligase	NA	NA	NA	NA
WP_087742156.1\|1611605_1614335_-	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	8.7e-89	44.3
WP_087742157.1\|1614542_1615184_-\|tRNA	DUF4479 and tRNA-binding domain-containing protein	NA	NA	NA	NA
WP_057734159.1\|1615206_1615539_-	thioredoxin family protein	NA	NA	NA	NA
WP_057734157.1\|1615877_1616204_+	hypothetical protein	NA	NA	NA	NA
WP_087742158.1\|1616322_1616826_-	universal stress protein	NA	NA	NA	NA
WP_087742159.1\|1616845_1618246_-	dipeptidase PepV	NA	NA	NA	NA
WP_087742160.1\|1618387_1619215_+	NAD(P)H-hydrate dehydratase	NA	NA	NA	NA
WP_087742161.1\|1619285_1619987_-	16S rRNA pseudouridylate synthase	NA	NA	NA	NA
WP_087742162.1\|1619999_1621643_-	polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_057734144.1\|1621916_1622240_+	hypothetical protein	NA	NA	NA	NA
WP_087742798.1\|1622396_1623161_+	flavodoxin family protein	NA	NA	NA	NA
WP_057734141.1\|1623971_1626407_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	66.1
WP_087742163.1\|1626809_1627448_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_057734138.1\|1627447_1628014_+	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	5.0e-31	41.8
WP_087742137.1\|1628506_1629721_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_087742164.1\|1629968_1630403_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_087742165.1\|1630509_1632177_+	acetolactate synthase AlsS	NA	NA	NA	NA
WP_087742166.1\|1632196_1632910_+	acetolactate decarboxylase	NA	NA	NA	NA
WP_087742167.1\|1633045_1634308_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	1.1e-49	33.2
WP_087742168.1\|1634459_1635317_+	sialate O-acetylesterase	NA	NA	NA	NA
WP_087742169.1\|1635313_1635823_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_087742170.1\|1635889_1636348_+	nitroreductase family protein	NA	NA	NA	NA
WP_087742171.1\|1636393_1637731_-	glycosyltransferase	NA	NA	NA	NA
WP_087742799.1\|1637735_1638266_-	hypothetical protein	NA	NA	NA	NA
WP_087742172.1\|1638249_1639098_-	EAL domain-containing protein	NA	NA	NA	NA
WP_157667868.1\|1639387_1639864_+	hypothetical protein	NA	NA	NA	NA
WP_087741240.1\|1640119_1641382_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	3.7e-50	33.2
WP_087742174.1\|1641620_1642358_-	adaptor protein MecA	NA	NA	NA	NA
WP_057734432.1\|1642509_1642911_-	transcriptional regulator Spx	NA	NA	NA	NA
WP_087742175.1\|1643012_1643753_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_057734428.1\|1643875_1644379_+	monooxygenase	NA	NA	NA	NA
WP_087742176.1\|1644462_1645686_+	DUF2075 domain-containing protein	NA	NA	NA	NA
WP_057733399.1\|1652824_1653214_-	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_057733396.1\|1653252_1653840_-	peptidylprolyl isomerase	A0A1V0SCU1	Indivirus	6.6e-26	42.6
WP_087742177.1\|1653960_1654470_+	phosphatidylglycerophosphatase A	G3MBC5	Bacillus_virus	3.5e-36	50.0
WP_087742178.1\|1655370_1656633_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	3.7e-50	33.2
WP_082619714.1\|1656714_1657659_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	8.9e-41	36.2
WP_015473476.1\|1657681_1658611_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9

DBSCAN-SWA_18

1757336 : 1811683

Streptococcus_phage(18.75%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087742237.1\|1757336_1758599_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	5.7e-51	33.4
WP_057733232.1\|1758818_1759676_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_087742238.1\|1760002_1761646_-	hypothetical protein	M1HE48	Acanthocystis_turfacea_Chlorella_virus	5.0e-07	43.2
WP_087742239.1\|1761653_1762793_-	D-alanine--D-alanine ligase	NA	NA	NA	NA
WP_015473476.1\|1762970_1763900_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_057733226.1\|1763914_1764889_-	DUF2785 domain-containing protein	NA	NA	NA	NA
WP_087742805.1\|1764922_1765777_-	hypothetical protein	NA	NA	NA	NA
WP_057733222.1\|1765920_1766223_-	glycine cleavage system protein H	NA	NA	NA	NA
WP_057733221.1\|1766239_1767445_-	rod shape-determining protein RodA	NA	NA	NA	NA
WP_057733219.1\|1767541_1767766_-	DUF2969 domain-containing protein	NA	NA	NA	NA
WP_057733217.1\|1767779_1768079_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.9e-20	59.4
WP_087742240.1\|1768102_1769107_-	rod shape-determining protein	NA	NA	NA	NA
WP_087742241.1\|1769232_1770546_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_057733211.1\|1770572_1770803_-	DUF1146 domain-containing protein	NA	NA	NA	NA
WP_087742242.1\|1771025_1771445_-	F0F1 ATP synthase subunit epsilon	NA	NA	NA	NA
WP_087742243.1\|1771458_1772874_-	F0F1 ATP synthase subunit beta	NA	NA	NA	NA
WP_057733207.1\|1772896_1773796_-	F0F1 ATP synthase subunit gamma	NA	NA	NA	NA
WP_087742244.1\|1773826_1775371_-	F0F1 ATP synthase subunit alpha	NA	NA	NA	NA
WP_057733203.1\|1775401_1775944_-	F0F1 ATP synthase subunit delta	NA	NA	NA	NA
WP_057733201.1\|1775933_1776449_-	F0F1 ATP synthase subunit B	NA	NA	NA	NA
WP_024746921.1\|1776495_1776708_-	F0F1 ATP synthase subunit C	NA	NA	NA	NA
WP_057733199.1\|1776744_1777461_-	F0F1 ATP synthase subunit A	NA	NA	NA	NA
WP_087741240.1\|1777848_1779111_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	3.7e-50	33.2
WP_057804547.1\|1779262_1779892_-	uracil phosphoribosyltransferase	NA	NA	NA	NA
WP_087742245.1\|1779986_1781228_-	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	3.2e-91	50.9
WP_087742247.1\|1781387_1782404_-	threonylcarbamoyl-AMP synthase	S4VW33	Pandoravirus	5.6e-49	40.0
WP_087742248.1\|1782416_1783265_-	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_057733190.1\|1783257_1784343_-	peptide chain release factor 1	NA	NA	NA	NA
WP_057733188.1\|1784363_1784948_-	thymidine kinase	A0A1W6JJU6	Lactococcus_phage	5.5e-49	51.0
WP_057733186.1\|1785192_1786542_+	Mur ligase family protein	NA	NA	NA	NA
WP_057733184.1\|1786538_1787243_+	glutamine amidotransferase	NA	NA	NA	NA
WP_087742249.1\|1787381_1788401_-	serine hydrolase	NA	NA	NA	NA
WP_087742806.1\|1788472_1789906_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_172825254.1\|1790012_1791929_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	1.8e-56	31.3
WP_087742251.1\|1791846_1793580_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.3e-41	26.7
WP_057733175.1\|1794006_1794336_+	hypothetical protein	NA	NA	NA	NA
WP_057733173.1\|1794390_1794594_-	hypothetical protein	NA	NA	NA	NA
WP_087742252.1\|1794682_1795807_-	diguanylate cyclase	A0A127AWB9	Bacillus_phage	1.0e-19	34.5
WP_087742253.1\|1796110_1796785_+	EAL domain-containing protein	NA	NA	NA	NA
WP_087742254.1\|1796917_1798177_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	1.1e-49	33.3
WP_087509149.1\|1798206_1798981_+\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.9e-25	49.5
WP_087742255.1\|1799179_1800223_-	LCP family protein	NA	NA	NA	NA
WP_087742256.1\|1800355_1801786_-	amino acid permease	NA	NA	NA	NA
WP_057733165.1\|1801934_1802597_-	TrkA family potassium uptake protein	NA	NA	NA	NA
WP_057733163.1\|1802609_1803965_-	ATP synthase subunit J	NA	NA	NA	NA
WP_087742257.1\|1804144_1805062_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	2.1e-63	46.8
WP_087742258.1\|1805227_1806460_-	MFS transporter	NA	NA	NA	NA
WP_087742259.1\|1806577_1807399_-	ATP-dependent sacrificial sulfur transferase LarE	NA	NA	NA	NA
WP_087742260.1\|1807410_1808655_-	nickel pincer cofactor biosynthesis protein LarC	NA	NA	NA	NA
WP_087742261.1\|1808667_1809420_-	nickel pincer cofactor biosynthesis protein LarB	A0A288TYA6	Enterococcus_phage	2.5e-17	43.1
WP_087742262.1\|1809416_1810580_-	nickel-dependent lactate racemase	NA	NA	NA	NA
WP_087742263.1\|1810657_1811683_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	2.0e-38	34.8

DBSCAN-SWA_19

1846004 : 1897458

Lactococcus_phage(18.18%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_057733083.1\|1846004_1848491_-\|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	3.2e-122	38.9
WP_057733081.1\|1848508_1848976_-	CtsR family transcriptional regulator	NA	NA	NA	NA
WP_057733080.1\|1850495_1851767_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	2.3e-84	48.4
WP_087742272.1\|1852052_1852685_-	deoxynucleoside kinase	C1KFI3	Lactobacillus_virus	1.2e-49	45.5
WP_057733408.1\|1852910_1854404_-	amino acid permease	NA	NA	NA	NA
WP_157667869.1\|1854769_1855303_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_087742275.1\|1855413_1856205_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_087742276.1\|1856275_1856944_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_057733069.1\|1857052_1857502_-	threonine/serine exporter family protein	NA	NA	NA	NA
WP_087742277.1\|1857514_1858276_-	threonine/serine exporter family protein	NA	NA	NA	NA
WP_057733064.1\|1858432_1859080_-	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_057733062.1\|1859132_1860032_-	cation transporter	NA	NA	NA	NA
WP_087742278.1\|1860205_1860766_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_087742808.1\|1861285_1861714_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_012695418.1\|1861995_1863021_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	5.7e-41	35.5
WP_057733057.1\|1863151_1864639_+	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_087742279.1\|1864638_1865361_+	DUF4811 domain-containing protein	NA	NA	NA	NA
WP_057733053.1\|1865529_1865769_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_087742280.1\|1865988_1866693_+	AzlC family ABC transporter permease	NA	NA	NA	NA
WP_057733049.1\|1866683_1867016_+	AzlD domain-containing protein	NA	NA	NA	NA
WP_057733047.1\|1867123_1867519_-	hypothetical protein	NA	NA	NA	NA
WP_172825279.1\|1867756_1868296_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_057733043.1\|1868533_1869274_-	DUF1003 domain-containing protein	NA	NA	NA	NA
WP_087742282.1\|1869287_1870172_-	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_057733039.1\|1870190_1870508_-	glycine cleavage system H protein (lipoate-binding)	NA	NA	NA	NA
WP_057733037.1\|1870639_1870828_+	hypothetical protein	NA	NA	NA	NA
WP_057733406.1\|1871278_1871842_-	sugar O-acetyltransferase	NA	NA	NA	NA
WP_087742284.1\|1871951_1873376_-	L-arabinose isomerase	NA	NA	NA	NA
WP_057733033.1\|1873427_1874156_-	L-ribulose-5-phosphate 4-epimerase	NA	NA	NA	NA
WP_087742285.1\|1874173_1875775_-	FGGY-family carbohydrate kinase	NA	NA	NA	NA
WP_087742286.1\|1875811_1877209_-	sugar porter family MFS transporter	NA	NA	NA	NA
WP_057733028.1\|1877617_1878718_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_083485315.1\|1878947_1879544_-	sugar O-acetyltransferase	NA	NA	NA	NA
WP_087742287.1\|1879663_1881439_-	DNA helicase RecQ	A0A2K9L021	Tupanvirus	1.6e-75	36.2
WP_087742288.1\|1881584_1883288_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_087742289.1\|1883475_1884882_+	C69 family dipeptidase	NA	NA	NA	NA
WP_087742290.1\|1884961_1885792_-	tyrosine-protein phosphatase	NA	NA	NA	NA
WP_191982776.1\|1885840_1886341_-	hypothetical protein	NA	NA	NA	NA
WP_057733016.1\|1886561_1886873_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_087742291.1\|1887047_1888970_+\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.5e-103	40.2
WP_172825280.1\|1888911_1889565_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_057732841.1\|1889582_1890221_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_057732839.1\|1890217_1891054_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_172825281.1\|1891072_1891804_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.5e-35	38.2
WP_015473476.1\|1891951_1892881_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_087741887.1\|1893521_1894538_-\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	1.4e-36	32.8
WP_157667870.1\|1895329_1895479_+	hypothetical protein	NA	NA	NA	NA
WP_031263932.1\|1895490_1896228_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	2.5e-59	50.4
WP_087741748.1\|1896237_1897458_-\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	1.2e-103	49.1

DBSCAN-SWA_20

1912757 : 1956337

Planktothrix_phage(37.5%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157667871.1\|1912757_1913591_-\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_157667872.1\|1913732_1913906_-	hypothetical protein	NA	NA	NA	NA
WP_087742304.1\|1913918_1915262_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_087741233.1\|1915580_1916036_-\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	5.1e-18	37.0
WP_087742305.1\|1916370_1917996_-	NAD-dependent malic enzyme	NA	NA	NA	NA
WP_087742306.1\|1918127_1919012_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_087742307.1\|1919106_1919538_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_087742308.1\|1919610_1920120_+	DUF2798 domain-containing protein	NA	NA	NA	NA
WP_157667836.1\|1920478_1921312_-\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_087742137.1\|1921516_1922731_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_083485307.1\|1923213_1924173_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.0e-19	34.0
WP_057732903.1\|1924172_1925273_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-17	29.1
WP_057732856.1\|1925286_1926315_-	ABC transporter permease	NA	NA	NA	NA
WP_057732854.1\|1926326_1927256_-	ABC transporter permease	NA	NA	NA	NA
WP_087742309.1\|1927459_1929091_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_087742310.1\|1929406_1931044_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_087742311.1\|1931664_1933293_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_087742312.1\|1933491_1935132_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_087742313.1\|1935306_1936599_+	GTPase HflX	NA	NA	NA	NA
WP_087742314.1\|1936792_1938715_+\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.5e-103	40.2
WP_172825280.1\|1938656_1939310_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_057732841.1\|1939327_1939966_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_057732839.1\|1939962_1940799_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_172825281.1\|1940817_1941549_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.5e-35	38.2
WP_015473476.1\|1941696_1942626_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_087742316.1\|1942889_1943852_-	hypothetical protein	NA	NA	NA	NA
WP_087742317.1\|1943872_1944424_-	hypothetical protein	NA	NA	NA	NA
WP_087742318.1\|1944498_1944957_-	transcriptional repressor	NA	NA	NA	NA
WP_057732829.1\|1945041_1945602_-	guanylate kinase	A0A143DIC6	Abalone_herpesvirus	4.6e-13	32.6
WP_087742319.1\|1945598_1946018_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_057732825.1\|1946319_1947714_+	amino acid permease	NA	NA	NA	NA
WP_087742320.1\|1947821_1950260_+	Xaa-Pro dipeptidyl-peptidase	NA	NA	NA	NA
WP_087742321.1\|1950333_1951242_+	proline-specific peptidase family protein	NA	NA	NA	NA
WP_057732819.1\|1951304_1951922_-	sugar O-acetyltransferase	NA	NA	NA	NA
WP_057732814.1\|1952098_1952707_-	L,D-transpeptidase	NA	NA	NA	NA
WP_087742322.1\|1952910_1953459_-	L,D-transpeptidase	NA	NA	NA	NA
WP_057732810.1\|1953483_1955037_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L0W2	Tupanvirus	2.9e-49	28.0
WP_087742323.1\|1955230_1955614_+	VOC family protein	NA	NA	NA	NA
WP_087742324.1\|1955641_1956337_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_21

1977208 : 2034194

unidentified_phage(23.08%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087742336.1\|1977208_1978138_+\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_087742337.1\|1978224_1979217_-	NAD(P)/FAD-dependent oxidoreductase	G3MA85	Bacillus_virus	9.7e-22	30.5
WP_087742338.1\|1979264_1980023_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_057732771.1\|1980007_1981051_-\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_057732769.1\|1981242_1982199_+	nucleoside hydrolase	NA	NA	NA	NA
WP_015473476.1\|1982312_1983242_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_087742339.1\|1983367_1984024_-	hypothetical protein	NA	NA	NA	NA
WP_087742340.1\|1984100_1984916_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_157667873.1\|1985773_1987075_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_087742342.1\|1987150_1987975_-	HAD family phosphatase	NA	NA	NA	NA
WP_087509149.1\|1988145_1988921_-\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.9e-25	49.5
WP_087742343.1\|1988960_1990148_-	D-alanyl-D-alanine carboxypeptidase	NA	NA	NA	NA
WP_087742344.1\|1990396_1991572_-	D-alanyl-D-alanine carboxypeptidase	NA	NA	NA	NA
WP_057732753.1\|1992008_1992575_+	ECF transporter S component	NA	NA	NA	NA
WP_087742345.1\|1992591_1994001_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	9.9e-12	27.5
WP_087742346.1\|1993997_1994651_+	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_087742347.1\|1994669_1995320_+	thiaminase II	NA	NA	NA	NA
WP_057732745.1\|1995400_1995763_+	hypothetical protein	NA	NA	NA	NA
WP_157058827.1\|1996088_1996262_-	hypothetical protein	NA	NA	NA	NA
WP_057732743.1\|1996553_1996748_+	hypothetical protein	NA	NA	NA	NA
WP_157667874.1\|1997339_1997594_-	zinc ribbon domain-containing protein	NA	NA	NA	NA
WP_087742348.1\|1997583_1997946_-	hypothetical protein	NA	NA	NA	NA
WP_087742349.1\|1997964_1999128_-	hypothetical protein	NA	NA	NA	NA
WP_057732735.1\|1999215_2000190_-	asparaginase	NA	NA	NA	NA
WP_087742350.1\|2000721_2002110_+	purine permease	Q9KX94	Enterobacteria_phage	9.1e-34	30.9
WP_057732731.1\|2002278_2003175_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	2.6e-18	29.4
WP_087742351.1\|2003167_2004379_+	ABC transporter permease	NA	NA	NA	NA
WP_087742352.1\|2004393_2004765_+	hypothetical protein	NA	NA	NA	NA
WP_087742353.1\|2005015_2005441_+\|transposase	transposase family protein	A0A1S5SBP9	Streptococcus_phage	6.6e-12	33.8
WP_087742354.1\|2005437_2006367_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	1.1e-19	29.9
WP_087742294.1\|2007457_2009014_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.1e-14	27.3
WP_087742295.1\|2009082_2009676_-	hypothetical protein	NA	NA	NA	NA
WP_057732886.1\|2009688_2010612_-	type I pantothenate kinase	A0A1B1ISL9	uncultured_Mediterranean_phage	1.1e-27	33.6
WP_087742296.1\|2010762_2013075_-	AAA family ATPase	NA	NA	NA	NA
WP_087742297.1\|2013245_2015102_+	monovalent cation:proton antiporter family protein	NA	NA	NA	NA
WP_087742298.1\|2015150_2015816_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_087742299.1\|2015915_2017973_-	alpha-glucosidase	NA	NA	NA	NA
WP_087742300.1\|2017974_2019312_-	hypothetical protein	NA	NA	NA	NA
WP_087742301.1\|2019315_2019984_-	hypothetical protein	H8ZMU3	Synechococcus_phage	8.2e-33	37.3
WP_087742302.1\|2020029_2021313_-	MFS transporter	NA	NA	NA	NA
WP_157667836.1\|2021352_2022186_-\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_172825255.1\|2022355_2022577_-	hypothetical protein	NA	NA	NA	NA
WP_087742356.1\|2022671_2024210_-	hypothetical protein	NA	NA	NA	NA
WP_057732717.1\|2024481_2025207_-	nicotinamide mononucleotide transporter	NA	NA	NA	NA
WP_087742357.1\|2025209_2025944_-	nucleoside phosphorylase	NA	NA	NA	NA
WP_057732898.1\|2025948_2026614_-	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_087742358.1\|2026908_2028282_-	DUF2252 domain-containing protein	NA	NA	NA	NA
WP_087742359.1\|2028468_2029032_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_087742360.1\|2029046_2030924_+	asparagine synthase (glutamine-hydrolyzing)	R4TIC1	Phaeocystis_globosa_virus	5.5e-26	26.4
WP_157667876.1\|2030993_2031362_-	hypothetical protein	NA	NA	NA	NA
WP_157667877.1\|2031443_2032034_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_087742362.1\|2032408_2032909_-	N-acetyltransferase	NA	NA	NA	NA
WP_015473476.1\|2033264_2034194_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9

DBSCAN-SWA_22

2049672 : 2099014

Paenibacillus_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087509149.1\|2049672_2050447_+\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.9e-25	49.5
WP_057732674.1\|2050548_2050998_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_087742375.1\|2051137_2051578_+	hypothetical protein	NA	NA	NA	NA
WP_087742376.1\|2051528_2053262_-\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.4e-103	40.2
WP_057732896.1\|2053431_2055006_-	APC family permease	NA	NA	NA	NA
WP_087742377.1\|2055300_2056011_-	VIT family protein	NA	NA	NA	NA
WP_087742378.1\|2056027_2056714_-	VIT family protein	NA	NA	NA	NA
WP_057732665.1\|2056989_2057499_+	transcriptional repressor	NA	NA	NA	NA
WP_012695418.1\|2058118_2059144_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	5.7e-41	35.5
WP_087742812.1\|2060009_2061131_+	N-acetylmuramoyl-L-alanine amidase	J3RJW9	Listeria_phage	2.2e-14	32.0
WP_057732664.1\|2061242_2062010_-	YibE/F family protein	NA	NA	NA	NA
WP_087742380.1\|2062006_2063122_-	YibE/F family protein	NA	NA	NA	NA
WP_087742381.1\|2063511_2063937_-	universal stress protein	NA	NA	NA	NA
WP_087742382.1\|2064155_2065037_+	hypothetical protein	NA	NA	NA	NA
WP_057732656.1\|2065258_2065756_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_087742383.1\|2065917_2067873_+	peptidase M13	A0A1V0SHG2	Klosneuvirus	1.1e-72	28.4
WP_087742384.1\|2068244_2069252_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_087742385.1\|2069287_2070751_-	UDP-glucose--hexose-1-phosphate uridylyltransferase	NA	NA	NA	NA
WP_057732650.1\|2070750_2071755_-	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	4.7e-56	39.4
WP_087742386.1\|2072180_2073350_-	galactokinase	NA	NA	NA	NA
WP_087742813.1\|2073500_2074517_-	MFS transporter	NA	NA	NA	NA
WP_087742387.1\|2074567_2075488_-\|transposase	IS30 family transposase	H7BW61	unidentified_phage	8.4e-20	29.9
WP_087509149.1\|2075507_2076283_-\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.9e-25	49.5
WP_157667878.1\|2076393_2076828_-	MFS transporter	NA	NA	NA	NA
WP_057732644.1\|2076880_2077120_-	hypothetical protein	NA	NA	NA	NA
WP_087742388.1\|2077403_2077643_-	hypothetical protein	NA	NA	NA	NA
WP_087742389.1\|2077844_2079575_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	2.5e-174	52.9
WP_087742390.1\|2079652_2080672_-	galactose mutarotase	NA	NA	NA	NA
WP_057732636.1\|2080916_2081138_-	hypothetical protein	NA	NA	NA	NA
WP_087742391.1\|2081156_2082878_-	hypothetical protein	NA	NA	NA	NA
WP_087742392.1\|2083127_2083949_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_087742393.1\|2084373_2085228_+	hypothetical protein	NA	NA	NA	NA
WP_057732626.1\|2085396_2086818_-	MFS transporter	NA	NA	NA	NA
WP_057732624.1\|2087058_2087238_+	hypothetical protein	NA	NA	NA	NA
WP_057732621.1\|2087373_2088165_+	type I methionyl aminopeptidase	NA	NA	NA	NA
WP_087742394.1\|2088183_2088906_+	demethylmenaquinone methyltransferase	NA	NA	NA	NA
WP_057732618.1\|2089266_2090124_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_057732616.1\|2090167_2090812_-	DNA-3-methyladenine glycosylase	NA	NA	NA	NA
WP_087742395.1\|2090934_2091327_+	DUF488 family protein	NA	NA	NA	NA
WP_087742396.1\|2091265_2091952_-	beta-phosphoglucomutase family hydrolase	NA	NA	NA	NA
WP_057732610.1\|2092074_2092533_-	universal stress protein	NA	NA	NA	NA
WP_057732895.1\|2092699_2094289_-	BCCT family transporter	NA	NA	NA	NA
WP_087742397.1\|2095215_2095818_-	sugar O-acetyltransferase	A0A191KBJ5	Streptococcus_virus	7.7e-06	30.3
WP_083485301.1\|2095938_2096403_-	glyoxalase/bleomycin resistance/extradiol dioxygenase family protein	NA	NA	NA	NA
WP_087742398.1\|2096441_2097323_-	viroplasmin family protein	C1KFJ1	Lactobacillus_virus	2.0e-31	37.6
WP_087742399.1\|2097604_2098078_+	hypothetical protein	NA	NA	NA	NA
WP_087742400.1\|2098239_2099014_+\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.9e-25	49.5

DBSCAN-SWA_23

2102058 : 2228932

115

Bacillus_phage(15.15%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087742137.1\|2102058_2103273_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_087742402.1\|2103523_2103703_-	hypothetical protein	NA	NA	NA	NA
WP_087742403.1\|2103695_2104388_-	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_170218382.1\|2104484_2104634_-	hypothetical protein	NA	NA	NA	NA
WP_087742404.1\|2104733_2105039_-	hypothetical protein	NA	NA	NA	NA
WP_057730439.1\|2105289_2105871_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_087742405.1\|2106034_2107825_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	1.1e-60	27.7
WP_087742406.1\|2108005_2108422_+	hypothetical protein	NA	NA	NA	NA
WP_087741233.1\|2108640_2109096_-\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	5.1e-18	37.0
WP_024746588.1\|2109312_2109516_-	cold-shock protein	Q9AZD3	Lactococcus_phage	1.2e-19	68.8
WP_087742407.1\|2109704_2110313_-	hypothetical protein	NA	NA	NA	NA
WP_057730430.1\|2110324_2110645_-	hypothetical protein	NA	NA	NA	NA
WP_087742408.1\|2110658_2111789_-	A/G-specific adenine glycosylase	NA	NA	NA	NA
WP_087742409.1\|2113653_2113977_-	hypothetical protein	NA	NA	NA	NA
WP_087742410.1\|2113979_2115014_-	lipoate--protein ligase	A0A2H4UVX5	Bodo_saltans_virus	4.9e-08	28.6
WP_057730423.1\|2115186_2115570_+	glycine cleavage system protein H	NA	NA	NA	NA
WP_057730421.1\|2115703_2115919_+	hypothetical protein	NA	NA	NA	NA
WP_015473476.1\|2116304_2117234_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_172825282.1\|2117230_2118013_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_087742411.1\|2118246_2118915_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_087742412.1\|2119084_2120464_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_152318961.1\|2120475_2121171_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.8e-31	34.8
WP_087742413.1\|2121315_2121945_-	histidine phosphatase family protein	NA	NA	NA	NA
WP_057732515.1\|2121961_2122876_-	EamA family transporter	NA	NA	NA	NA
WP_015473476.1\|2123415_2124345_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_010620880.1\|2124552_2125578_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	2.3e-42	36.1
WP_172825283.1\|2125724_2126369_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_083485298.1\|2126408_2127473_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	1.0e-32	35.8
WP_057732518.1\|2127531_2128335_-	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_087742415.1\|2128881_2129430_-	DNA-3-methyladenine glycosylase I	NA	NA	NA	NA
WP_087742416.1\|2129544_2131185_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_087742417.1\|2131596_2133849_+	glycoside hydrolase family 3 C-terminal domain-containing protein	NA	NA	NA	NA
WP_157667901.1\|2133911_2134805_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.7e-33	42.7
WP_087742418.1\|2135337_2135787_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_087742419.1\|2135800_2136784_-	choloylglycine hydrolase family protein	M1HWD6	Paramecium_bursaria_Chlorella_virus	1.0e-23	29.7
WP_087742420.1\|2136946_2140114_-	SMC family ATPase	NA	NA	NA	NA
WP_087742421.1\|2140113_2141244_-	exonuclease SbcCD subunit D	A0A142F1G8	Bacillus_phage	1.8e-08	25.2
WP_172825256.1\|2141247_2141823_-	DNA-3-methyladenine glycosylase I	NA	NA	NA	NA
WP_087742423.1\|2142042_2142975_+\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_057732537.1\|2143117_2144068_+	1,4-beta-N-acetylmuramidase	A0A160LKP9	Bacillus_phage	7.6e-24	36.2
WP_087742424.1\|2144181_2145303_-	endoglucanase	NA	NA	NA	NA
WP_087742425.1\|2145323_2145983_-	hypothetical protein	NA	NA	NA	NA
WP_087742426.1\|2146214_2146841_+	response regulator transcription factor	NA	NA	NA	NA
WP_057734466.1\|2146913_2147240_-	metal-sulfur cluster assembly factor	NA	NA	NA	NA
WP_057734464.1\|2147526_2147721_-	hypothetical protein	NA	NA	NA	NA
WP_087742427.1\|2148087_2148426_+	hypothetical protein	NA	NA	NA	NA
WP_057734460.1\|2148482_2149211_-	PAS domain-containing protein	NA	NA	NA	NA
WP_087742429.1\|2149664_2150840_+\|transposase	IS256 family transposase	NA	NA	NA	NA
WP_087742430.1\|2150856_2151252_+\|transposase	transposase	A0A1X9I619	Streptococcus_phage	2.4e-16	45.1
WP_057733530.1\|2151485_2151686_-	hypothetical protein	NA	NA	NA	NA
WP_087742431.1\|2151951_2152452_-	hypothetical protein	NA	NA	NA	NA
WP_057733527.1\|2152743_2153481_-	DUF1129 domain-containing protein	NA	NA	NA	NA
WP_057734458.1\|2154864_2155758_-	L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha	NA	NA	NA	NA
WP_057734456.1\|2155771_2156431_-	L-serine ammonia-lyase, iron-sulfur-dependent, subunit beta	NA	NA	NA	NA
WP_087742432.1\|2156500_2157172_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_087742433.1\|2157229_2157712_+\|transposase	transposase	NA	NA	NA	NA
WP_157667901.1\|2157684_2158578_+\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.7e-33	42.7
WP_087742434.1\|2158566_2158992_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_057734678.1\|2159324_2160596_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	2.2e-95	44.3
WP_087741233.1\|2161358_2161814_-\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	5.1e-18	37.0
WP_057734676.1\|2162074_2163343_-	NAD(P)H-dependent oxidoreductase	A0A2P0ZL82	Lactobacillus_phage	8.8e-60	61.3
WP_087742435.1\|2163360_2163969_-	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	1.7e-56	55.0
WP_057734673.1\|2164057_2164969_-	FAD:protein FMN transferase	NA	NA	NA	NA
WP_057734671.1\|2165188_2165728_+	hypothetical protein	NA	NA	NA	NA
WP_087742436.1\|2165856_2167710_+	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	1.4e-85	35.1
WP_057734668.1\|2167746_2168067_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_087742437.1\|2168429_2169911_+	MFS transporter	NA	NA	NA	NA
WP_087742438.1\|2170299_2170821_-	hypothetical protein	NA	NA	NA	NA
WP_087742439.1\|2170941_2171967_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	3.6e-35	34.5
WP_057734661.1\|2172502_2174083_-	FGGY-family carbohydrate kinase	NA	NA	NA	NA
WP_057734659.1\|2174240_2175017_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_087742440.1\|2175242_2176349_+	ROK family transcriptional regulator	NA	NA	NA	NA
WP_087742441.1\|2176413_2177766_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_087742442.1\|2178161_2178809_+	DNA-3-methyladenine glycosylase 2 family protein	NA	NA	NA	NA
WP_087742443.1\|2178944_2179817_+	DegV family protein	NA	NA	NA	NA
WP_087742444.1\|2179893_2180511_-	NAD(P)H-binding protein	NA	NA	NA	NA
WP_087742445.1\|2180603_2181167_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_087742446.1\|2181356_2182106_+	DUF4811 domain-containing protein	NA	NA	NA	NA
WP_057734644.1\|2182282_2183698_-	NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta	NA	NA	NA	NA
WP_057734642.1\|2183694_2184009_-	NAD(P) transhydrogenase subunit alpha	NA	NA	NA	NA
WP_057734640.1\|2184011_2185244_-	NAD(P) transhydrogenase subunit alpha	NA	NA	NA	NA
WP_157667881.1\|2185636_2186095_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_087509149.1\|2186207_2186983_-\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.9e-25	49.5
WP_087742448.1\|2187022_2188402_-	hypothetical protein	A0A2P0ZL91	Lactobacillus_phage	1.8e-18	40.3
WP_087742449.1\|2188842_2189388_+	LysM peptidoglycan-binding domain-containing protein	A0A2K9V574	Lactobacillus_phage	4.8e-15	60.6
WP_087742450.1\|2189716_2190118_+	transglycosylase	A0A0E3XCL7	Enterococcus_phage	9.3e-16	58.6
WP_087742451.1\|2190959_2192306_-	APC family permease	NA	NA	NA	NA
WP_087742452.1\|2192533_2193913_+	DHA2 family efflux MFS transporter permease subunit	A0A0M3UL24	Mycobacterium_phage	2.2e-11	22.3
WP_087742453.1\|2194078_2195095_-	adenosine deaminase	NA	NA	NA	NA
WP_087742454.1\|2195264_2196614_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	7.9e-51	34.3
WP_087742455.1\|2196623_2198393_+	adenine deaminase	NA	NA	NA	NA
WP_087742456.1\|2198485_2198797_-	hypothetical protein	NA	NA	NA	NA
WP_087741887.1\|2198880_2199897_+\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	1.4e-36	32.8
WP_045808046.1\|2200455_2200707_-	hypothetical protein	NA	NA	NA	NA
WP_087742458.1\|2200754_2200973_-	hypothetical protein	NA	NA	NA	NA
WP_057733565.1\|2201235_2201928_-	2,3-diphosphoglycerate-dependent phosphoglycerate mutase	NA	NA	NA	NA
WP_157667882.1\|2202093_2203656_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_057733561.1\|2203848_2204955_-	AI-2E family transporter	NA	NA	NA	NA
WP_087742459.1\|2205197_2206382_-	ROK family protein	NA	NA	NA	NA
WP_087742460.1\|2206882_2207809_-	hypothetical protein	NA	NA	NA	NA
WP_057733556.1\|2208005_2209199_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_057733554.1\|2209772_2210117_-	AzlD domain-containing protein	NA	NA	NA	NA
WP_087742461.1\|2210135_2210939_-	AzlC family ABC transporter permease	NA	NA	NA	NA
WP_087742462.1\|2211179_2214491_-	YhgE/Pip domain-containing protein	NA	NA	NA	NA
WP_172825284.1\|2214931_2216239_-	serine hydrolase	B6DZZ7	Stx2-converting_phage	4.0e-15	26.6
WP_057733599.1\|2216310_2217486_-	sensor histidine kinase	W8CYF6	Bacillus_phage	9.1e-27	29.9
WP_057733546.1\|2217496_2218186_-	response regulator transcription factor	W8CYM9	Bacillus_phage	9.7e-37	36.7
WP_087742464.1\|2218880_2219447_+\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_057733542.1\|2219601_2220741_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	2.3e-59	33.1
WP_087742465.1\|2221002_2222712_-	hypothetical protein	NA	NA	NA	NA
WP_087742466.1\|2222749_2224402_-	glycosyltransferase family 39 protein	NA	NA	NA	NA
WP_087742467.1\|2224569_2224953_-	hypothetical protein	NA	NA	NA	NA
WP_157667883.1\|2225142_2225715_-	hypothetical protein	NA	NA	NA	NA
WP_057733533.1\|2226066_2226441_-	hypothetical protein	NA	NA	NA	NA
WP_087742430.1\|2228536_2228932_+\|transposase	transposase	A0A1X9I619	Streptococcus_phage	2.4e-16	45.1

DBSCAN-SWA_24

2241931 : 2293308

unidentified_phage(20.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087742475.1\|2241931_2243107_+\|transposase	IS256 family transposase	NA	NA	NA	NA
WP_087742476.1\|2243138_2243984_-	hypothetical protein	NA	NA	NA	NA
WP_057733504.1\|2246049_2246316_-	hypothetical protein	NA	NA	NA	NA
WP_087742477.1\|2246643_2247213_+	hypothetical protein	NA	NA	NA	NA
WP_057733500.1\|2247344_2247605_+	hypothetical protein	NA	NA	NA	NA
WP_057733498.1\|2247672_2248062_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_087742478.1\|2248268_2249081_-	hypothetical protein	NA	NA	NA	NA
WP_172825257.1\|2249431_2250064_+	hypothetical protein	NA	NA	NA	NA
WP_172825258.1\|2250122_2250872_-	MucBP domain-containing protein	NA	NA	NA	NA
WP_087742481.1\|2251121_2252486_-	hypothetical protein	NA	NA	NA	NA
WP_087509149.1\|2252641_2253416_+\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.9e-25	49.5
WP_087742482.1\|2253516_2254920_-	S-layer protein	NA	NA	NA	NA
WP_157667884.1\|2255089_2256325_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	2.6e-48	33.0
WP_012695418.1\|2256478_2257504_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	5.7e-41	35.5
WP_015473476.1\|2257818_2258748_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_087742485.1\|2259262_2259493_+	hypothetical protein	NA	NA	NA	NA
WP_087742486.1\|2259841_2260750_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_087742487.1\|2260829_2261054_-	DUF2922 domain-containing protein	NA	NA	NA	NA
WP_087742488.1\|2261087_2261285_-	hypothetical protein	NA	NA	NA	NA
WP_057733478.1\|2261377_2261944_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_087742489.1\|2262233_2263286_+	hypothetical protein	NA	NA	NA	NA
WP_087742490.1\|2263808_2265983_-	cell wall anchor protein	NA	NA	NA	NA
WP_087742491.1\|2266429_2268355_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	4.8e-33	40.0
WP_087742492.1\|2268417_2269080_-	thiamine phosphate synthase	NA	NA	NA	NA
WP_087742493.1\|2269079_2269895_-	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_057733468.1\|2269915_2270704_-	hydroxyethylthiazole kinase	NA	NA	NA	NA
WP_087742494.1\|2270982_2271819_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_083485330.1\|2272194_2273640_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	6.7e-80	35.6
WP_057733464.1\|2273711_2274152_+	DUF2628 domain-containing protein	NA	NA	NA	NA
WP_087742495.1\|2274247_2274997_-	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	2.3e-23	32.9
WP_087742496.1\|2275005_2276016_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_087742497.1\|2276012_2276792_-	ABC transporter permease	G3M9Y4	Bacillus_virus	4.6e-19	27.6
WP_087742498.1\|2276979_2278683_-	FAD-dependent oxidoreductase	E4WM79	Ostreococcus_tauri_virus	5.2e-07	30.7
WP_087742816.1\|2278702_2279980_-	YeeE/YedE family protein	NA	NA	NA	NA
WP_087742499.1\|2280181_2281111_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_087742500.1\|2281580_2282435_+	DUF368 domain-containing protein	NA	NA	NA	NA
WP_087742501.1\|2282529_2282799_-	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_057733444.1\|2285443_2285689_-	hypothetical protein	NA	NA	NA	NA
WP_087742502.1\|2285872_2286529_+	hypothetical protein	NA	NA	NA	NA
WP_087742503.1\|2286601_2286889_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_087742504.1\|2287201_2288065_-	hypothetical protein	NA	NA	NA	NA
WP_087742505.1\|2288229_2289123_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_087742506.1\|2289289_2290084_+	tyrosine-protein phosphatase	NA	NA	NA	NA
WP_087742507.1\|2290199_2291012_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_087742508.1\|2291364_2291901_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_015473476.1\|2292378_2293308_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9

DBSCAN-SWA_25

2331302 : 2395937

unidentified_phage(33.33%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015473476.1\|2331302_2332232_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_087742533.1\|2332524_2334036_-	xylulokinase	NA	NA	NA	NA
WP_057732435.1\|2334250_2335600_-	xylose isomerase	NA	NA	NA	NA
WP_087742534.1\|2335827_2337015_-	ROK family protein	NA	NA	NA	NA
WP_087742535.1\|2337331_2338444_-	hypothetical protein	NA	NA	NA	NA
WP_057734470.1\|2338606_2339524_-	SPFH/Band 7/PHB domain protein	NA	NA	NA	NA
WP_087742536.1\|2339525_2339732_-	hypothetical protein	NA	NA	NA	NA
WP_087742537.1\|2339842_2340055_+	hypothetical protein	NA	NA	NA	NA
WP_087742538.1\|2340043_2340571_-	hypothetical protein	NA	NA	NA	NA
WP_087742539.1\|2341128_2344899_+	MucBP domain-containing protein	NA	NA	NA	NA
WP_087742540.1\|2345463_2349417_+	MucBP domain-containing protein	NA	NA	NA	NA
WP_087742541.1\|2349495_2350551_-	zinc-dependent alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_087742542.1\|2350702_2351650_-	WYL domain-containing protein	NA	NA	NA	NA
WP_191982778.1\|2352047_2352641_+	hypothetical protein	NA	NA	NA	NA
WP_087742543.1\|2352777_2354016_-	hypothetical protein	NA	NA	NA	NA
WP_157667887.1\|2354203_2354377_+	hypothetical protein	NA	NA	NA	NA
WP_087742544.1\|2354373_2354901_-	hypothetical protein	NA	NA	NA	NA
WP_087742545.1\|2355080_2356388_+	DNA/RNA non-specific endonuclease	NA	NA	NA	NA
WP_087741887.1\|2356732_2357749_+\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	1.4e-36	32.8
WP_087742546.1\|2357778_2358021_-	ATP-binding protein	NA	NA	NA	NA
WP_015473476.1\|2358048_2358978_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_087742548.1\|2359860_2360970_+	glycerol dehydrogenase	NA	NA	NA	NA
WP_087742549.1\|2361311_2362682_-	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_087742550.1\|2363080_2364406_-	replication-associated recombination protein A	G3MBE0	Bacillus_virus	1.8e-92	41.5
WP_057734490.1\|2364430_2364757_-	hypothetical protein	NA	NA	NA	NA
WP_057734491.1\|2364916_2365372_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_057734492.1\|2365405_2366053_+	NAD(P)H-hydrate epimerase	NA	NA	NA	NA
WP_087742551.1\|2366160_2366712_+	M15 family metallopeptidase	NA	NA	NA	NA
WP_087742818.1\|2367200_2368127_+	DMT family transporter	NA	NA	NA	NA
WP_087742552.1\|2368503_2369979_-	aldehyde dehydrogenase	NA	NA	NA	NA
WP_087742553.1\|2370029_2371151_-	NAD(P)-dependent alcohol dehydrogenase	E3SJ82	Synechococcus_phage	2.1e-20	26.0
WP_087742554.1\|2371595_2372222_-	DUF2975 domain-containing protein	NA	NA	NA	NA
WP_087742555.1\|2372381_2373338_+	linear amide C-N hydrolase	M1I9Z8	Acanthocystis_turfacea_Chlorella_virus	1.1e-11	29.3
WP_087742556.1\|2373491_2373974_+	C40 family peptidase	A0A217EQL1	Bacillus_phage	3.9e-08	39.2
WP_087742557.1\|2374109_2374451_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_087742558.1\|2374668_2376642_-	S9 family peptidase	NA	NA	NA	NA
WP_087742559.1\|2376834_2377764_+	2-dehydropantoate 2-reductase	NA	NA	NA	NA
WP_057733834.1\|2377951_2378227_+	hypothetical protein	NA	NA	NA	NA
WP_057733836.1\|2378396_2378795_-	transcriptional regulator Spx	NA	NA	NA	NA
WP_087742560.1\|2379730_2381752_+	sodium:proton antiporter	NA	NA	NA	NA
WP_015473476.1\|2381841_2382771_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_087742562.1\|2383210_2384791_+	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_157667888.1\|2384872_2385658_-	hypothetical protein	NA	NA	NA	NA
WP_057733844.1\|2385784_2387389_-	ribonuclease Y	NA	NA	NA	NA
WP_087742564.1\|2387488_2388175_-	DUF1275 domain-containing protein	NA	NA	NA	NA
WP_087742565.1\|2388190_2389135_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_087742566.1\|2389285_2391109_+	M3 family oligoendopeptidase	NA	NA	NA	NA
WP_057733851.1\|2391179_2391602_+	helix-turn-helix transcriptional regulator	A0A2R2ZGJ3	Clostridioides_phage	7.8e-05	43.4
WP_087742567.1\|2391748_2392600_+	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_057733855.1\|2392722_2392995_+	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_083485341.1\|2392994_2393375_+	replication associated protein	NA	NA	NA	NA
WP_087742568.1\|2393476_2393785_-	hypothetical protein	NA	NA	NA	NA
WP_057733858.1\|2393943_2394162_-	hypothetical protein	NA	NA	NA	NA
WP_087742569.1\|2394190_2394964_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_087742570.1\|2395160_2395937_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_26

2406986 : 2448641

unidentified_phage(18.18%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015473476.1\|2406986_2407916_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_057731725.1\|2408122_2410510_-	phosphoketolase family protein	NA	NA	NA	NA
WP_057731722.1\|2411185_2411911_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_057731719.1\|2412089_2412593_+\|tRNA	Cys-tRNA(Pro) deacylase	NA	NA	NA	NA
WP_087742582.1\|2412596_2413403_+	hypothetical protein	NA	NA	NA	NA
WP_087742583.1\|2413454_2414216_+	NUDIX hydrolase	NA	NA	NA	NA
WP_087742584.1\|2414321_2415527_+	MFS transporter	NA	NA	NA	NA
WP_087742585.1\|2415498_2416332_+	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_087742586.1\|2417531_2417780_+	hypothetical protein	NA	NA	NA	NA
WP_087742819.1\|2417932_2418688_+	YdcF family protein	NA	NA	NA	NA
WP_087742587.1\|2418736_2419981_-	hypothetical protein	NA	NA	NA	NA
WP_087741887.1\|2420973_2421990_+\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	1.4e-36	32.8
WP_021355909.1\|2422709_2423900_-	NarK/NasA family nitrate transporter	NA	NA	NA	NA
WP_087742589.1\|2423904_2424903_-	GTP 3',8-cyclase MoaA	NA	NA	NA	NA
WP_011101425.1\|2424946_2425192_-	MoaD/ThiS family protein	NA	NA	NA	NA
WP_087742590.1\|2425194_2425596_-	molybdenum cofactor biosynthesis protein MoaE	NA	NA	NA	NA
WP_087742591.1\|2425993_2426449_+	flavodoxin	NA	NA	NA	NA
WP_087742592.1\|2426452_2427454_+	iron ABC transporter permease	NA	NA	NA	NA
WP_087742593.1\|2427450_2428221_+	ABC transporter ATP-binding protein	A0A1V0SGN0	Hokovirus	3.2e-12	31.0
WP_087742594.1\|2428337_2429408_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003640267.1\|2429424_2430831_-	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
WP_087742595.1\|2430827_2431295_-	SUF system NifU family Fe-S cluster assembly protein	NA	NA	NA	NA
WP_087742596.1\|2431281_2432520_-	cysteine desulfurase	Q2XUY6	environmental_halophage	2.1e-106	46.4
WP_003645199.1\|2432503_2433805_-	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
WP_003640263.1\|2433817_2434615_-	Fe-S cluster assembly ATPase SufC	A0A285PWH2	Cedratvirus	1.8e-10	25.5
WP_003640262.1\|2434870_2435095_+	ferrous iron transport protein A	NA	NA	NA	NA
WP_087742597.1\|2435096_2437085_+	ferrous iron transport protein B	NA	NA	NA	NA
WP_011101416.1\|2437101_2437266_+	FeoB-associated Cys-rich membrane protein	NA	NA	NA	NA
WP_087742598.1\|2437505_2439197_-\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.3e-103	40.2
WP_087742820.1\|2439619_2440822_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_087741748.1\|2440994_2442215_+\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	1.2e-103	49.1
WP_031263932.1\|2442224_2442962_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	2.5e-59	50.4
WP_087742599.1\|2443120_2444374_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	2.1e-50	32.4
WP_087742601.1\|2444569_2445499_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	2.5e-19	29.5
WP_172825260.1\|2445646_2446057_-	hypothetical protein	NA	NA	NA	NA
WP_087742603.1\|2446071_2447037_-	hypothetical protein	NA	NA	NA	NA
WP_157667901.1\|2447292_2448186_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.7e-33	42.7
WP_087742433.1\|2448158_2448641_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_27

2460644 : 2514976

unidentified_phage(41.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015473476.1\|2460644_2461574_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_087742604.1\|2462643_2463297_+	response regulator transcription factor	NA	NA	NA	NA
WP_011101432.1\|2463614_2463923_+	hypothetical protein	NA	NA	NA	NA
WP_087742605.1\|2463932_2464910_+	hypothetical protein	NA	NA	NA	NA
WP_087742606.1\|2464924_2465824_+	hypothetical protein	NA	NA	NA	NA
WP_087742607.1\|2466024_2466903_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_087742608.1\|2466932_2467271_-	metal-sulfur cluster assembly factor	NA	NA	NA	NA
WP_010620880.1\|2467421_2468447_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	2.3e-42	36.1
WP_015473476.1\|2468554_2469484_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_087742609.1\|2469584_2470988_-	MFS transporter	NA	NA	NA	NA
WP_057734085.1\|2471146_2471803_-	HD domain-containing protein	S4W232	Pandoravirus	4.0e-16	36.1
WP_087742610.1\|2471795_2472446_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_015473476.1\|2472759_2473689_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_087742612.1\|2473710_2475393_+	family 43 glycosylhydrolase	NA	NA	NA	NA
WP_087742613.1\|2475394_2476627_+	MFS transporter	NA	NA	NA	NA
WP_087742614.1\|2476712_2477222_-	hypothetical protein	NA	NA	NA	NA
WP_087742615.1\|2477384_2478575_-	acetate kinase	NA	NA	NA	NA
WP_087742616.1\|2478757_2479114_-	aggregation promoting factor surface protein	A0A249XZV3	Enterococcus_phage	2.0e-14	52.9
WP_087742617.1\|2479355_2480036_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_057734063.1\|2480362_2480605_-	hypothetical protein	NA	NA	NA	NA
WP_057734060.1\|2480822_2481443_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_057734058.1\|2482017_2484633_-	bifunctional acetaldehyde-CoA/alcohol dehydrogenase	NA	NA	NA	NA
WP_087742618.1\|2485039_2486833_+	glycerophosphoryl diester phosphodiesterase membrane domain-containing protein	A0A220BYK6	Staphylococcus_phage	5.5e-07	24.9
WP_087742619.1\|2486956_2487607_-	nitroreductase family protein	NA	NA	NA	NA
WP_087742620.1\|2487619_2488513_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_087742621.1\|2488658_2489084_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_087742622.1\|2489321_2489777_-\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	2.3e-18	37.7
WP_087742623.1\|2489974_2490502_-	DUF1836 domain-containing protein	NA	NA	NA	NA
WP_087742624.1\|2490592_2492947_-	cation-translocating P-type ATPase	A0A1J0FA34	Only_Syngen_Nebraska_virus	5.1e-29	24.2
WP_170218393.1\|2493123_2493282_+	hypothetical protein	NA	NA	NA	NA
WP_087742625.1\|2493686_2494535_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	2.5e-58	43.4
WP_087742626.1\|2494609_2495038_-	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
WP_057734040.1\|2495283_2496342_-	sugar transferase	NA	NA	NA	NA
WP_157667889.1\|2496705_2496846_-	hypothetical protein	NA	NA	NA	NA
WP_087742627.1\|2496970_2499337_+	accessory Sec system translocase SecA2	NA	NA	NA	NA
WP_015473476.1\|2499346_2500276_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_057734038.1\|2500404_2501640_+	hypothetical protein	NA	NA	NA	NA
WP_087742629.1\|2501652_2503194_+	accessory Sec system protein Asp1	NA	NA	NA	NA
WP_087742630.1\|2503177_2504761_+	accessory Sec system protein Asp2	NA	NA	NA	NA
WP_057734033.1\|2504757_2505510_+	accessory Sec system protein Asp3	NA	NA	NA	NA
WP_087742631.1\|2505506_2506955_+	glycosyltransferase	NA	NA	NA	NA
WP_057734029.1\|2506944_2507811_+	hypothetical protein	NA	NA	NA	NA
WP_157667890.1\|2508079_2513995_-	accessory Sec-dependent LPXTG-anchored adhesin	NA	NA	NA	NA
WP_015473476.1\|2514046_2514976_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9

DBSCAN-SWA_28

2603622 : 2653037

Lactobacillus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087742674.1\|2603622_2604063_-\|transposase	IS200/IS605 family transposase	A0A0P0IQC6	Lactobacillus_phage	3.4e-35	56.7
WP_087742675.1\|2604156_2605419_+\|transposase	transposase	A0A286QQE5	Streptococcus_phage	4.4e-51	35.3
WP_057732150.1\|2605839_2606205_-	hypothetical protein	NA	NA	NA	NA
WP_057732148.1\|2606304_2606907_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_057732146.1\|2607063_2608047_+	aldo/keto reductase	NA	NA	NA	NA
WP_172825285.1\|2608311_2609613_+	NCS2 family permease	NA	NA	NA	NA
WP_087742676.1\|2609672_2610080_-	hypothetical protein	NA	NA	NA	NA
WP_087742677.1\|2610076_2610484_-	hypothetical protein	NA	NA	NA	NA
WP_087742678.1\|2610492_2610732_-	hypothetical protein	NA	NA	NA	NA
WP_087742679.1\|2610760_2611171_-	hypothetical protein	NA	NA	NA	NA
WP_087742680.1\|2611236_2611827_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_087742681.1\|2611951_2612839_+	NAD(P)H-binding protein	NA	NA	NA	NA
WP_087742682.1\|2612988_2613774_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_057732121.1\|2613770_2614715_-	citrate lyase	NA	NA	NA	NA
WP_087742683.1\|2614870_2616025_+	NADP-dependent malic enzyme	NA	NA	NA	NA
WP_087742684.1\|2616635_2617691_+	[citrate (pro-3S)-lyase] ligase	NA	NA	NA	NA
WP_087742685.1\|2617708_2618266_+	citrate lyase holo-[acyl-carrier protein] synthase	NA	NA	NA	NA
WP_087742686.1\|2618265_2619117_+	triphosphoribosyl-dephospho-CoA synthase CitG	NA	NA	NA	NA
WP_087742687.1\|2619178_2619472_-	hypothetical protein	NA	NA	NA	NA
WP_087742688.1\|2619797_2620061_-	hypothetical protein	NA	NA	NA	NA
WP_087742689.1\|2620358_2621252_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_057732105.1\|2621282_2622821_-	citrate lyase subunit alpha	NA	NA	NA	NA
WP_087742690.1\|2622810_2623725_-	citrate (pro-3S)-lyase subunit beta	NA	NA	NA	NA
WP_057732101.1\|2623727_2624021_-	citrate lyase acyl carrier protein	NA	NA	NA	NA
WP_087742691.1\|2624580_2625999_-	anion permease	NA	NA	NA	NA
WP_087742692.1\|2626067_2627462_-	flavocytochrome c	A0A2P0ZL82	Lactobacillus_phage	2.9e-56	32.1
WP_057732096.1\|2627487_2628054_-	NAD(P)H-dependent oxidoreductase	A0A2P0ZL82	Lactobacillus_phage	1.9e-46	50.6
WP_057732094.1\|2628163_2629546_-	class II fumarate hydratase	NA	NA	NA	NA
WP_087742693.1\|2630025_2630886_-	FAD synthetase family protein	NA	NA	NA	NA
WP_057732090.1\|2630958_2632704_-	pyruvate oxidase	NA	NA	NA	NA
WP_087742694.1\|2634191_2635145_-	L-lactate dehydrogenase	NA	NA	NA	NA
WP_087742695.1\|2635367_2635973_-	pyroglutamyl-peptidase I	NA	NA	NA	NA
WP_087742696.1\|2636056_2639155_-	YfhO family protein	NA	NA	NA	NA
WP_057730529.1\|2639355_2639877_+	QueT transporter family protein	E7DN70	Pneumococcus_phage	1.0e-06	30.5
WP_087742697.1\|2639923_2641735_-	DUF2207 domain-containing protein	NA	NA	NA	NA
WP_087742698.1\|2641977_2643672_+\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.3e-103	40.2
WP_057730532.1\|2643796_2645281_-	cardiolipin synthase	NA	NA	NA	NA
WP_157058824.1\|2645367_2645523_+	hypothetical protein	NA	NA	NA	NA
WP_087742699.1\|2645600_2646413_-	DNA/RNA non-specific endonuclease	NA	NA	NA	NA
WP_087742700.1\|2646634_2647174_+	hypothetical protein	NA	NA	NA	NA
WP_057730521.1\|2647286_2647547_+	hypothetical protein	NA	NA	NA	NA
WP_057730520.1\|2647906_2648302_+	D-ribose pyranase	NA	NA	NA	NA
WP_057730518.1\|2648360_2649722_+	L-fucose:H+ symporter permease	NA	NA	NA	NA
WP_015473476.1\|2649954_2650884_+\|transposase	IS30-like element ISLpl1 family transposase	H7BW61	unidentified_phage	8.5e-20	29.9
WP_087742822.1\|2651013_2652030_+\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	1.0e-34	31.0
WP_087742702.1\|2652107_2653037_-\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	8.0e-26	29.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LT854705

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection