CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Prophage number
NZ_CP054435	Staphylococcus saprophyticus strain UTI-035 plasmid pUTI-035-1, complete sequence	0 crisprs	NA	0
NZ_CP054437	Staphylococcus saprophyticus strain UTI-035 plasmid pUTI-035-3, complete sequence	0 crisprs	NA	0
NZ_CP054434	Staphylococcus saprophyticus strain UTI-035 chromosome, complete genome	2 crisprs	csa3,WYL,DEDDh,cas3,DinG	7
NZ_CP054436	Staphylococcus saprophyticus strain UTI-035 plasmid pUTI-035-2, complete sequence	0 crisprs	csa3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP054434_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP054434_1

323247-323344

Orphan

Consensus_repeat	Method
TTGCATAAGAATCACTAAGGAAATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP054434_1

>merge|NZ_CP054434|1|323247-323344|CRISPRCasFinder
TTGCATAAGAATCACTAAGGAAATTCGTAACATTAATTTCCAAGTGAAATTAATGAATACAAAAGAAAATCTTTTGCATAAGAATCACTAAGGAAATT

>NZ_CP054434|1|1|323247-323344|CRISPRCasFinder
TTGCATAAGAATCACTAAGGAAATT	CGTAACATTAATTTCCAAGTGAAATTAATGAATACAAAAGAAAATCTT
TTGCATAAGAATCACTAAGGAAATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054434.1\|WP_011302240.1\|323351_324641_-\|homocysteine-synthase	unknown	unknown	gnl\|CDD\|225428
NZ_CP054434.1\|WP_011302236.1\|318818_319574_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP054434.1\|WP_061050467.1\|313618_313939_+\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99906
NZ_CP054434.1\|WP_002482214.1\|330058_330901_-\|urease-accessory-protein-UreD	unknown	unknown	gnl\|CDD\|223899
NZ_CP054434.1\|WP_011302246.1\|329765_329972_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP054434.1\|WP_011302242.1\|325760_326906_+\|bifunctional-cystathionine-gamma-lyase/homocysteine-desulfhydrase	unknown	unknown	gnl\|CDD\|181076
NZ_CP054434.1\|WP_002482211.1\|328389_328944_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP054434.1\|WP_061050468.1\|313982_314276_+\|PTS-lactose/cellobiose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|376749
NZ_CP054434.1\|WP_047504698.1\|324858_325764_+\|cysteine-synthase-family-protein	unknown	unknown	gnl\|CDD\|107204
NZ_CP054434.1\|WP_011302235.1\|317687_318605_-\|2-dehydropantoate-2-reductase	unknown	unknown	gnl\|CDD\|183829
NZ_CP054434.1\|WP_011302247.1\|330901_331516_-\|urease-accessory-protein-UreG	unknown	unknown	gnl\|CDD\|349776
NZ_CP054434.1\|WP_011302248.1\|331529_332219_-\|urease-accessory-protein-UreF	unknown	unknown	gnl\|CDD\|223900
NZ_CP054434.1\|WP_077461027.1\|321875_322946_+\|ROK-family-protein	unknown	unknown	gnl\|CDD\|224851
NZ_CP054434.1\|WP_011302232.1\|314509_315304_+\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270429
NZ_CP054434.1\|WP_011302237.1\|319915_320734_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_CP054434.1\|WP_011302245.1\|329117_329588_-\|acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|223894
NZ_CP054434.1\|WP_002482217.1\|332211_332664_-\|urease-accessory-protein-UreE	unknown	unknown	gnl\|CDD\|237322
NZ_CP054434.1\|WP_011302233.1\|315287_316007_+\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_CP054434.1\|WP_011302238.1\|320777_321710_+\|lactate-dehydrogenase	unknown	unknown	gnl\|CDD\|133426
NZ_CP054434.1\|WP_002482190.1\|316003_316735_+\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051

Protein	Function_ID	Function_description	E-value
NZ_CP054434.1\|WP_011302240.1\|323351_324641_-\|homocysteine-synthase	gnl\|CDD\|225428	COG2873, MET17, O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism].	0
NZ_CP054434.1\|WP_011302236.1\|318818_319574_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	3.72315e-10
NZ_CP054434.1\|WP_061050467.1\|313618_313939_+\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|99906	cd05564, PTS_IIB_chitobiose_lichenan, PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N,N-diacetylchitobiose-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain. In the chitobiose system, these subunits are expressed as separate proteins from chbA, chbB, and chbC of the chb operon (formerly the cel (cellulose) operon). In the lichenan system, these subunits are expressed from licA, licB, and licC of the lic operon. The lic operon of Bacillus subtilis is required for the transport and degradation of oligomeric beta-glucosides, which are produced by extracellular enzymes on substrates such as lichenan or barley glucan. The lic operon is transcribed from a gammaA-dependent promoter and is inducible by lichenan, lichenan hydrolysate, and cellobiose. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include chitobiose/lichenan, ascorbate, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	6.47715e-45
NZ_CP054434.1\|WP_002482214.1\|330058_330901_-\|urease-accessory-protein-UreD	gnl\|CDD\|223899	COG0829, UreH, Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones].	1.83725e-86
NZ_CP054434.1\|WP_002482217.1\|332211_332664_-\|urease-accessory-protein-UreE	gnl\|CDD\|237322	PRK13261, ureE, urease accessory protein UreE; Provisional.	1.37227e-59
NZ_CP054434.1\|WP_011302242.1\|325760_326906_+\|bifunctional-cystathionine-gamma-lyase/homocysteine-desulfhydrase	gnl\|CDD\|181076	PRK07671, PRK07671, bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase.	0
NZ_CP054434.1\|WP_002482211.1\|328389_328944_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	6.36006e-12
NZ_CP054434.1\|WP_061050468.1\|313982_314276_+\|PTS-lactose/cellobiose-transporter-subunit-IIA	gnl\|CDD\|376749	pfam02255, PTS_IIA, PTS system, Lactose/Cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The lactose/cellobiose-specific family are one of four structurally and functionally distinct group IIA PTS system enzymes. This family of proteins normally function as a homotrimer, stabilized by a centrally located metal ion. Separation into subunits is thought to occur after phosphorylation.	7.38632e-37
NZ_CP054434.1\|WP_047504698.1\|324858_325764_+\|cysteine-synthase-family-protein	gnl\|CDD\|107204	cd01561, CBS_like, CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. Deficiency of CBS leads to homocystinuria, an inherited disease of sulfur metabolism characterized by increased levels of the toxic metabolite homocysteine. Cysteine synthase on the other hand catalyzes the last step of cysteine biosynthesis. This subgroup also includes an O-Phosphoserine sulfhydrylase found in hyperthermophilic archaea which produces L-cysteine from sulfide and the more thermostable O-phospho-L-serine.	3.06093e-108
NZ_CP054434.1\|WP_011302235.1\|317687_318605_-\|2-dehydropantoate-2-reductase	gnl\|CDD\|183829	PRK12921, PRK12921, oxidoreductase.	1.47135e-125
NZ_CP054434.1\|WP_011302247.1\|330901_331516_-\|urease-accessory-protein-UreG	gnl\|CDD\|349776	cd05540, UreG, urease accessory protein UreG. UreG is one of the four accessory proteins of urease. Urease is an enzyme which catalyzes the decomposition of urea to form ammonia and carbon dioxide. Bacterial urease is a trimer of three subunits which are encoded by genes ureA, ureB, and ureC. Up to four accessory proteins (ureD, ureE, ureF, and ureG) are required for urease catalytical function. UreG may play an important role in nickel incorporation of the urease metallocenter. UreG is a member of the Fer4_NifH superfamily which contains an ATP-binding domain. Proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion.	1.54103e-117
NZ_CP054434.1\|WP_011302248.1\|331529_332219_-\|urease-accessory-protein-UreF	gnl\|CDD\|223900	COG0830, UreF, Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones].	1.45042e-91
NZ_CP054434.1\|WP_077461027.1\|321875_322946_+\|ROK-family-protein	gnl\|CDD\|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	8.29114e-23
NZ_CP054434.1\|WP_011302232.1\|314509_315304_+\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270429	cd13711, PBP2_Ngo0372_TcyA, Substrate binding domain of ABC transporters involved in cystine import; the type 2 periplasmic binding protein fold. This subgroup includes cystine-binding domain of periplasmic receptor-dependent ATP-binding cassette transporters from Neisseria gonorrhoeae and Bacillus subtilis and their related proteins. Cystine is an oxidized dimeric form of cysteine that is required for optimal bacterial growth. In Bacillus subtilis, three ABC transporters, TcyJKLMN (YtmJKLMN), TcyABC (YckKJI), and YxeMNO are involved in uptake of cystine. Likewise, three uptake systems were identified in Salmonella enterica serovar Typhimurium, while in Escherichia coli, two transport systems seem to be involved in cystine uptake. Moreover, L-cystine limitation was shown to prevent virulence of Neisseria gonorrhoeae; thus, its L-cystine solute receptor (Ngo0372) may be suited as target for an antimicrobial vaccine. The cystine receptor belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.32092e-109
NZ_CP054434.1\|WP_011302237.1\|319915_320734_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	6.23317e-97
NZ_CP054434.1\|WP_011302245.1\|329117_329588_-\|acyl-CoA-thioesterase	gnl\|CDD\|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	5.61813e-26
NZ_CP054434.1\|WP_011302233.1\|315287_316007_+\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	6.40669e-78
NZ_CP054434.1\|WP_011302238.1\|320777_321710_+\|lactate-dehydrogenase	gnl\|CDD\|133426	cd05290, LDH_3, A subgroup of L-lactate dehydrogenases. L-lactate dehydrogenases (LDH) are tetrameric enzymes catalyzing the last step of glycolysis in which pyruvate is converted to L-lactate. This subgroup is composed of some bacterial LDHs from firmicutes, gammaproteobacteria, and actinobacteria. Vertebrate LDHs are non-allosteric, but some bacterial LDHs are activated by an allosteric effector such as fructose-1,6-bisphosphate. LDHs are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenase, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	8.30515e-159
NZ_CP054434.1\|WP_002482190.1\|316003_316735_+\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	8.94086e-142

>NZ_CP054434.1|WP_077461027.1|321875_322946_+|ROK-family-protein
MLERHVKLIRLMLINRNQFLNADEIARYLNVSNRTARNDIQYINSEILDDLIVSVKGRGYKLNQSLYSMQQIETIVTDFTNKESELLIKLGYQLLMYQQPLTSEAIGKTFHLTKAEVTDYINKIKAWCISFDVNIQITKKKGITVNGSEMNIRNAILHLNQLSENVKTVDAFILAEHQYMKHQTEDFIYLTISTGVGMAYIRKGELVSGVNGNFGEIGHTIIKGDSDYQCPVCKQYVCVENEISGLAISRKASHILNKHVSTREAIEMYLHQAHSEITEMIDEVLILTQQLCTNLFSIFNINNIVLGGGVTQSKLPYKSSIENYAQKHYLIQNSTLNVTISNLEANVLTGLYHVNK
>NZ_CP054434.1|WP_011302238.1|320777_321710_+|lactate-dehydrogenase
MSKLGIIGLGKVGTQVLTDVQQLNLFSEIILIDDRADVASGEALDHIHSQGLINTAHIKIRSGVYQDLTDADFIVIAASEATDKNNGDRTLLAQGNHDIIKGIMSQIAEVTQEAVVILISNPVDSMVYFANQIDYPAHKIIGTGTALETSRFKTIIADHYQIDPNNVEAFVIGEHGQHAIPVWSKVHIHGMELSEFEALSDRPAIDKSHISSIINEVSMDVFYQKGWTNAAISKVTSFLIQSIALDQRTITPLTSLSSEYGLEDGAFSLPTLIDKKGIVQRFAITLDKEEERELKEAYEYIRQTIHTAQQ
>NZ_CP054434.1|WP_011302237.1|319915_320734_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MRKWFILGSLFVLTIILAACGKSNGEKEDKEITIAASPAPHGVVLEHAKEEMKKKGYDLKIKTVNDYKVPNKLLDKGDVDANAFQHTPYLKAEKKDHNYKIEEAGKVFTTPMGVYSKKYKDIKDIPKGSTIYVSNNPAEEGRFLSFFVDKGLIKIKKGVSIEDAKFDDIVENKKDLKFNNKQGAEFLPKTYNSKEGAAVIMNSNYAIDNGLTPHKDAIAIEGKSSPFANIVAVQEGHKNDKKFKELMKVLQSKEMKKFITDKYGQDVIPYEK
>NZ_CP054434.1|WP_011302236.1|318818_319574_+|CPBP-family-intramembrane-metalloprotease
MSFKNDHKYQWKDMQGKDFLLPFIYLIGNFCLSIVILTIMIGINETQGKNNANFNANFSGTPGILMEMIAFIIIFALWILFHRHSFRQSWKQGLQNIKQHWKLIVITFIVIIVFKEIYPYLVNAFAPEHWKFEETQNDKMVEEMFATPVSTILAFFSIVIIAPMTEEFLFRHLIIGELGKKLNFYVMSVISIIVFASLHVTEAKSPLEIVMYLAIAVGIVYVYMKSQRSLAVAIALHALNNLLAYIFMIIM
>NZ_CP054434.1|WP_011302235.1|317687_318605_-|2-dehydropantoate-2-reductase
MRILVLGAGGIGGYFGGRLAESGQNVTFLVRPKRKSFLERNGLAIHSEQGDYHFNPQLITKDDRVAPFDVILLSSKSYHLEQAMTDLKPFVDGHTAIIPLLNGVAHIPQLQSIFGKDKVMGGYCVIETTLDSMGEIIQTSPFDKLFFGELDGSKSERAQKIAQAFSETKAEFKLSTSIEQGMWHKYLMITVLSSITTLMHAPIGPIRDSDGGINFVRSLYNEVASIMRAHRAPLADDIVSQYMTSFNQLSYHFKTSMQRDMEKGLNIETGHLQGYLLNLADTYQIDAPLLKCVYQNHKVYKEMLK
>NZ_CP054434.1|WP_002482190.1|316003_316735_+|amino-acid-ABC-transporter-ATP-binding-protein
MIELKNIKKSFDDKEVIKGIDLNVNQGEVVTFIGRSGSGKTTLLRMINALELPTEGAVYVNGETYSNADKKSQIKVRKQSGMVFQSYNLFPHKTALENVMEGLITVKKTKKDEAKQQALALLEKVDLTAVKDQRPNALSGGQQQRVAIARALAMNPKVMLFDEPTSALDPELVNDVLRVIKDLANEGMTMIIVTHEMRFAKEVSNKIVFIHDGVIGESGPPEQIFNHPQSAELQRFLNMIREV
>NZ_CP054434.1|WP_011302233.1|315287_316007_+|amino-acid-ABC-transporter-permease
MFLNLNTEQQHALDAAGQAFAPMLEGLVKFSIPITLVTFLLGLVIALLTALMRISTSRILRGIARFYISIIRGTPMIVQLFIIFYGIPELGRLLTNNSENQWTLAPVIAAIIGLSLNVGAYASEIIRGGIMSIPKGQTEAAYSIGMNYRQTIQRIILPQAIRVSVPALGNTFLSLIKDTSLLGFILVAEMFRKAQEVASTTYEYLTIYLLVALMYWVVCFIISIAQNFYESYLERGYRS
>NZ_CP054434.1|WP_011302232.1|314509_315304_+|amino-acid-ABC-transporter-substrate-binding-protein
MKKILLGILTLLLVVGLAACGTSDKKDNDNKNKTASENKTFVVGTEGTYAPFSYHDKQDKLTGYDIDVMKAVAKEMGYKVKFKETQWDSMFAGLDSGRFNVIANQVGINDERKEKYKFSEPYTYSEAVLVVNKNNKDIKSFDDVKGKKLAQTFTSNYGKLAKSKGAELTKVDGFNQAMDLLQSNRVEGTFNDNISYLDYKKQKPNADVKIIEGNAEKSQSALTFSKKEDDATIEKVNKAMKKLKDNGELAKISKKWFGEDVSKS
>NZ_CP054434.1|WP_061050468.1|313982_314276_+|PTS-lactose/cellobiose-transporter-subunit-IIA
MSLIAYSGDAKSHAMEAIYAAKKNAFEEAEKKLKLAEVSLLEAHHIQTNMLTKEAQGDEIKMSLLTIHSQDHLMTAITFKDMAAEMIDLYKKMDSKA
>NZ_CP054434.1|WP_061050467.1|313618_313939_+|PTS-sugar-transporter-subunit-IIB
MAEKTIMLVCAAGMSTSMLVQKMQKEAEKQKLDRDIFAVSTSEADQKIESDNIDVLLLGPQVRFKKDEYTKKCSEKDIPVAVIEMRDYGTMNGENVLNTAEQLMKK
>NZ_CP054434.1|WP_011302240.1|323351_324641_-|homocysteine-synthase
MTQNPWHLDTLSIHGGQVVDDFSKARAVPIYQTSSYVFDNTEHARKLFALEEDGNIYTRIMNPTQNVFEERIAALEGGVGALATSSGQAAIHLALLNIVESGDEIVASSNLYGGTYNLLNITFKKLGIKVHFVDPSHPDNFKNAITDKTKAVYAETIGNPRIDVLDIEAVADIAHNHNIPLIVDNTFPTPYLLRPFEFGADIIVHSATKFIGGHGTSIGGVIVDSGKFNWDNGKFPGLVEPDESYHGISYAKDVGEAAYITKARVQLLRDLGSAVSPFNVHEFLIGLETLHLRLERHSENALRVAQYLEQHPKVTWVNYPGLKNNAYHQLAQKYLPDGQGAILTFGIDGTVDDIAKFVDGLNLFSHLANVGDSKSLIIHPASTTHLQLSPEDQKASGVVPELVRLSVGTENINDIIADLDNGFKESLGN
>NZ_CP054434.1|WP_047504698.1|324858_325764_+|cysteine-synthase-family-protein
MIAFDLIGNTPLVLLESFSNKDVQIYAKLEQYNLGGSVKDRLGKHLIETAIRENIIQKGDVVVEASAGNTGIGVAIAANHYGVSAVIFAPEGFSEEKISIIKALGAEVIRTDQTLGMAGAQKAARDYELQTGAYYLNQFESYRNPETYKSTIGKEITDKLKDIDYFVGGVGSGGTFTGVAEHLAATYHTESVIVEPEGSILSGGNAHSHDIEGIGSEKWPSFLPKALVSDIIKVSDDAAFQNVKLLARQEGLLVGSSSGAALQGALEIKKHINKGVIVTIFPDGSDRYMSKQILNYKETIK
>NZ_CP054434.1|WP_011302242.1|325760_326906_+|bifunctional-cystathionine-gamma-lyase/homocysteine-desulfhydrase
MNKKTQLIHGGQTTDPYTGAVTTPIYQTSTYMQDGIGDMRQGYEYSRSANPTRSALEGLIADLEQGESGFAFGSGMAAISAVIMLLDKGDHLLINSDVYGGTYRALTKVFNRFGIDAEFIDTTNIEAVEQYIKPETKMLYIETPSNPLLRVTDIKKSAEIAKKHHLISVVDNTFMTPYFQNPLTLGIDIVLHSATKYIGGHSDVVAGLVATSDAELAERLGFIQNSTGGVLGPQDSYLLIRGIKTLGLRMEQVQRNTLAIIDMLQQHSAVKQVFHPSISDHLNHDIHEAQSEGHTGVVAFEVADIESAKKVISESHYFTLAESLGAVESLISVPALMTHASIPKDIREKEGIADGLVRLSVGIEDTKDLVEDLEQSLNALG
>NZ_CP054434.1|WP_002482211.1|328389_328944_-|TetR/AcrR-family-transcriptional-regulator
MSQKKQDILSVAERLFYEYGFKGVGLKQIIQEANVATMTLYNHFESKDNLVAQVLKQRETRYWHYLDSHVEQHPEKPFISAVTAHCQWLNDYSYKGDMFMRAIEDYADTDNEIESTARGHKERLLHYLEKLADDAGIENGYDLAVQYTLLLEGTTSMTALLGSKDATSHAITMAKLLLNEAHNQ
>NZ_CP054434.1|WP_011302245.1|329117_329588_-|acyl-CoA-thioesterase
MTDEYIYKNTVQPSWIDNNNHMHDAQYYSIFSDAVVGFFESIDFSTDYRHSQDVTMFSVEAHISFLKELLLDESFYIKVHIYDYDAKRVHLFLTMYNSNDERNATYEAIMMGVGNETRRSMDFPKPIQEKIKHYFDQQNTFDVPKQLGHVIGIPKK
>NZ_CP054434.1|WP_011302246.1|329765_329972_+|hypothetical-protein
MVLVALILFIISIVFLIYSITLLMGKDGTMFSLFTKEEKALTKGQKLTIYLITIVLFVASLVWLLNLI
>NZ_CP054434.1|WP_002482214.1|330058_330901_-|urease-accessory-protein-UreD
MSNNKQAWTGQLDLSVFNNGKKSVARDVFFEKALKVMRPVYLNQSDIPTFYIVNVGGGYLDGDRYTMNFNIDSDAKVILTSQGATKIYKTLNDHVEQYQTFNIKNNGYAEYVGDPIIAFENAKFYQHNVFNLESTASLFYTDILTPGYSKSDKRFSYTYMHLLNEIYVDDALVTFDNMLLDPQKQNVDGLGYMEDYTHLGSCYFIHPSVNQKFIEQVYEEIKHFQHKYDCRFGITHLPTHGFSLRILSNKTQVIESIITAVQCYVVKQIFDRDVDFLRKY
>NZ_CP054434.1|WP_011302247.1|330901_331516_-|urease-accessory-protein-UreG
MTDTIKIGVGGPVGAGKTQLIEKIVKRLAKDMSIGVITNDIYTKEDEKILVNSGVLPEDRIIGVETGGCPHTAIREDASMNFAAIDELKERNDDIELIFIESGGDNLAATFSPELVDFSIYIIDVAQGEKIPRKGGQGMIKSDFFVINKTDLAPYVGASLDRMAEDTKVFRGNRPFTFTNLKTDEGLDEVIQWIEQDVFLKGLA
>NZ_CP054434.1|WP_011302248.1|331529_332219_-|urease-accessory-protein-UreF
MIDHAHLRLFQFCDSQFPTGAFSHSFGLETYIQRDTVHDEESFQQWLVLFLNEQLTYADGLTMRLVYDALNENDTKAILKLDRILFVQNLPKETRQGSKQMGNRMVKLASELYDSDWINWYHAQMKDKKASLHPAICFTMLGHHLGVDIETIIDYYLYQNVSSLTQNAVRAIPLGQTAGQRIVHKMIPIMKETRDHIMTIPASQLGITAPGLEINQMEHENVNVRIFIS
>NZ_CP054434.1|WP_002482217.1|332211_332664_-|urease-accessory-protein-UreE
MIIEEIVGNIANLSDSEKGKHMEKVYLENSDLVKRIQRVTTDHGNEIGIRLKQPIDLQYGDILYKDDKNMIVVDVNSEDLLVIKPRTLQEMGDIAHQLGNRHLPAQFTETEMLVQYDYLVESLLKDLGIPYEHEDRKVNKAFRHIGHSHD

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Crispr_ID: NZ_CP054434_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP054434_2

1434612-1434708

Orphan

Consensus_repeat	Method
CCCTTATCTCTTTATGAGATTAGGGGCTCTTAAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP054434_2

>merge|NZ_CP054434|2|1434612-1434708|CRISPRCasFinder
CCCTTATCTCTTTATGAGATTAGGGGCTCTTAATGCATGCGAAACCGCATGTATACCATTATACCCTTATCTCTTTATGAGATTAGGGGCGCTTAAT

>NZ_CP054434|2|2|1434612-1434708|CRISPRCasFinder
CCCTTATCTCTTTATGAGATTAGGGGCTCTTAAT	GCATGCGAAACCGCATGTATACCATTATA
CCCTTATCTCTTTATGAGATTAGGGGCGCTTAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054434.1\|WP_011303127.1\|1433239_1433509_-\|acylphosphatase	unknown	unknown	gnl\|CDD\|184677
NZ_CP054434.1\|WP_061050602.1\|1428184_1429528_+\|branched-chain-amino-acid-transport-system-II-carrier-protein	unknown	unknown	gnl\|CDD\|224039
NZ_CP054434.1\|WP_002483328.1\|1444699_1446304_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|237894
NZ_CP054434.1\|WP_047503746.1\|1438613_1439333_-\|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-acetyltransferase	unknown	unknown	gnl\|CDD\|132571
NZ_CP054434.1\|WP_011303124.1\|1429756_1431388_+\|BCCT-family-transporter	unknown	unknown	gnl\|CDD\|376718
NZ_CP054434.1\|WP_048787355.1\|1439355_1440078_-\|4-hydroxy-tetrahydrodipicolinate-reductase	unknown	unknown	gnl\|CDD\|234595
NZ_CP054434.1\|WP_048787356.1\|1437166_1438324_-\|amidohydrolase	unknown	unknown	gnl\|CDD\|349920
NZ_CP054434.1\|WP_001831260.1\|1434351_1434552_+\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
NZ_CP054434.1\|WP_047503755.1\|1432605_1433226_-\|5-bromo-4-chloroindolyl-phosphate-hydrolysis-family-protein	unknown	unknown	gnl\|CDD\|227252
NZ_CP054434.1\|WP_002483311.1\|1425365_1426157_+\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NZ_CP054434.1\|WP_047503752.1\|1434827_1436093_-\|diaminopimelate-decarboxylase	unknown	unknown	gnl\|CDD\|143501
NZ_CP054434.1\|WP_048787358.1\|1426169_1428062_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226921
NZ_CP054434.1\|WP_011303135.1\|1440963_1441953_-\|aspartate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|237845
NZ_CP054434.1\|WP_011303136.1\|1442003_1443212_-\|aspartate-kinase	unknown	unknown	gnl\|CDD\|235843
NZ_CP054434.1\|WP_011303134.1\|1440074_1440962_-\|4-hydroxy-tetrahydrodipicolinate-synthase	unknown	unknown	gnl\|CDD\|235107
NZ_CP054434.1\|WP_011303130.1\|1436096_1437170_-\|alanine-racemase	unknown	unknown	gnl\|CDD\|223858
NZ_CP054434.1\|WP_011303128.1\|1433855_1434164_+\|DUF1033-family-protein	unknown	unknown	gnl\|CDD\|227043
NZ_CP054434.1\|WP_047503758.1\|1431437_1432571_-\|toxic-anion-resistance-protein	unknown	unknown	gnl\|CDD\|377557
NZ_CP054434.1\|WP_047503768.1\|1425008_1425212_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP054434.1\|WP_011303137.1\|1443652_1444483_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381358

Protein	Function_ID	Function_description	E-value
NZ_CP054434.1\|WP_011303127.1\|1433239_1433509_-\|acylphosphatase	gnl\|CDD\|184677	PRK14431, PRK14431, acylphosphatase; Provisional.	4.01149e-54
NZ_CP054434.1\|WP_061050602.1\|1428184_1429528_+\|branched-chain-amino-acid-transport-system-II-carrier-protein	gnl\|CDD\|224039	COG1114, BrnQ, Branched-chain amino acid permeases [Amino acid transport and metabolism].	1.20551e-148
NZ_CP054434.1\|WP_002483328.1\|1444699_1446304_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|237894	PRK15064, PRK15064, ABC transporter ATP-binding protein; Provisional.	0
NZ_CP054434.1\|WP_047503746.1\|1438613_1439333_-\|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-acetyltransferase	gnl\|CDD\|132571	TIGR03532, DapD_Ac, 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase. This enzyme is part of the diaminopimelate pathway of lysine biosynthesis. Alternate name: tetrahydrodipicolinate N-acetyltransferase. Note that IUBMB lists this alternate name as the accepted name. Unfortunately, the related succinyl transferase acting on the same substrate (EC:2.3.1.117, TIGR00695) uses the opposite standard. We have decided to give these two enzymes names which more clearly indicated that they act on the same substrate.	4.04866e-128
NZ_CP054434.1\|WP_011303124.1\|1429756_1431388_+\|BCCT-family-transporter	gnl\|CDD\|376718	pfam02028, BCCT, BCCT, betaine/carnitine/choline family transporter.	5.75758e-159
NZ_CP054434.1\|WP_048787355.1\|1439355_1440078_-\|4-hydroxy-tetrahydrodipicolinate-reductase	gnl\|CDD\|234595	PRK00048, PRK00048, dihydrodipicolinate reductase; Provisional.	3.49108e-92
NZ_CP054434.1\|WP_048787356.1\|1437166_1438324_-\|amidohydrolase	gnl\|CDD\|349920	cd05670, M20_Acy1_YkuR-like, M20 Peptidase aminoacyclase-1 YkuR-like proteins, including YkuR and Ama/HipO/HyuC proteins. Peptidase M20 family, aminoacyclase-1 YkuR-like subfamily including YkuR and Ama/HipO/HyuC proteins, most of which have not been well characterized to date. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in the protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity; substrates include indoleacetic acid (IAA) N-conjugates of amino acids, N-acetyl-L-amino acids and aminobenzoylglutamate. ACY1 breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as in the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine). ACY1 appears to physically interact with Sphingosine kinase type 1 (SphK1) and may influence its physiological functions; SphK1 and its product sphingosine-1-phosphate have been shown to promote cell growth and inhibit apoptosis of tumor cells. Strong expression of the human gene and its mouse ortholog Acy1 in brain, liver, and kidney suggest a role of the enzyme in amino acid metabolism of these organs.	8.9551e-132
NZ_CP054434.1\|WP_011303130.1\|1436096_1437170_-\|alanine-racemase	gnl\|CDD\|223858	COG0787, Alr, Alanine racemase [Cell envelope biogenesis, outer membrane].	4.38828e-83
NZ_CP054434.1\|WP_047503755.1\|1432605_1433226_-\|5-bromo-4-chloroindolyl-phosphate-hydrolysis-family-protein	gnl\|CDD\|227252	COG4915, XpaC, 5-bromo-4-chloroindolyl phosphate hydrolysis protein [General function prediction only].	1.9189e-64
NZ_CP054434.1\|WP_002483311.1\|1425365_1426157_+\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	8.84495e-40
NZ_CP054434.1\|WP_047503752.1\|1434827_1436093_-\|diaminopimelate-decarboxylase	gnl\|CDD\|143501	cd06828, PLPDE_III_DapDC, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase. Diaminopimelate decarboxylase (DapDC, EC 4.1.1.20) participates in the last step of lysine biosynthesis. It converts meso-2,6-diaminoheptanedioate to L-lysine. It is a fold type III PLP-dependent enzyme that contains an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain, similar to bacterial alanine racemases. DapDC exists as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. Homodimer formation and the presence of the PLP cofactor are required for catalytic activity.	1.87416e-161
NZ_CP054434.1\|WP_048787358.1\|1426169_1428062_+\|hypothetical-protein	gnl\|CDD\|226921	COG4548, NorD, Nitric oxide reductase activation protein [Inorganic ion transport and metabolism].	0
NZ_CP054434.1\|WP_011303135.1\|1440963_1441953_-\|aspartate-semialdehyde-dehydrogenase	gnl\|CDD\|237845	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional.	4.95605e-151
NZ_CP054434.1\|WP_011303137.1\|1443652_1444483_-\|aldo/keto-reductase	gnl\|CDD\|381358	cd19132, AKR_AKR5D1_E1, AKR5D and AKR5E families of aldo-keto reductase (AKR). 2,5-diketo-D-gluconic acid reductase B (DkgB) from Corynebacterium sp. and 2,5-diketo-D-gluconic acid reductase Zymomonas mobilis are founding members of aldo-keto reductase family 5 member D1 (AKR5D1) and E1 (AKR5E1), respectively. DkgB (EC 1.1.1.274), also called 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming), or 2,5-DKG reductase B, or 2,5-DKGR B, or 25DKGR-B, catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).	1.86748e-153
NZ_CP054434.1\|WP_011303134.1\|1440074_1440962_-\|4-hydroxy-tetrahydrodipicolinate-synthase	gnl\|CDD\|235107	PRK03170, PRK03170, dihydrodipicolinate synthase; Provisional.	1.53604e-132
NZ_CP054434.1\|WP_001831260.1\|1434351_1434552_+\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	3.00557e-32
NZ_CP054434.1\|WP_011303128.1\|1433855_1434164_+\|DUF1033-family-protein	gnl\|CDD\|227043	COG4699, COG4699, Uncharacterized protein conserved in bacteria [Function unknown].	4.87771e-33
NZ_CP054434.1\|WP_047503758.1\|1431437_1432571_-\|toxic-anion-resistance-protein	gnl\|CDD\|377557	pfam05816, TelA, Toxic anion resistance protein (TelA). This family consists of several prokaryotic TelA like proteins. TelA and KlA are associated with tellurite resistance and plasmid fertility inhibition.	2.37294e-132
NZ_CP054434.1\|WP_011303136.1\|1442003_1443212_-\|aspartate-kinase	gnl\|CDD\|235843	PRK06635, PRK06635, aspartate kinase; Reviewed.	0

>NZ_CP054434.1|WP_001831260.1|1434351_1434552_+|cold-shock-protein
MKQGTVKWFNAEKGFGFIEVEGENDVFVHFSAINQEGYKSLEEGQSVEFEVVEGDRGPQAANVVKL
>NZ_CP054434.1|WP_011303128.1|1433855_1434164_+|DUF1033-family-protein
MWTVAKIRADYEGWWLFSDWTDQIVEQHNFETYDAMMAFYNALILKSKRHYDNYLVGKYNIHAFYNNCELGFCEDCDEDLQIFYSYIVLNNNEVYYNLPNIE
>NZ_CP054434.1|WP_011303127.1|1433239_1433509_-|acylphosphatase
MQRKHIKVFGMVQGVGFRYYTEKIAQKHNIVGTVENIDNYVDIYAQGDEPSLTEFINAVTEGASPASHVEDYTIEALDYDQSLKKFRTI
>NZ_CP054434.1|WP_047503755.1|1432605_1433226_-|5-bromo-4-chloroindolyl-phosphate-hydrolysis-family-protein
MRYNISRIFGTIIALPAAVIAWFASIFALDIYFIFDVLVAAATFIVFYFPTQRLTSRKYLREIGLSRRDYHFVNGQLNNAQDKIRRIFKTFVNVRSIKDFKQVNEIYRISRAIYFAVKQRPGSFFKVESFFYSHIDNALNLIEAYTRLSKSPKKSKEEKQKLEQTRITLDEVKRTLVADLRRINDEDYSQLDIEMELNKIEQKRNK
>NZ_CP054434.1|WP_047503758.1|1431437_1432571_-|toxic-anion-resistance-protein
MAREQDSINSHPLDKYIDENSANESEIIKSSSQFSHEDQQKIDKLSKQIKPMDNDGLLNYGTEAQSNMSQFSHRILNEVKTTDVGPVGDSLNGLMSKLKSVNPEELNPENQSKLKRIFKRTKASVNEIFSKMQSVGSQIDRISIELDKHKNNLKKDIDMLDELYDMNKDYFDELSIYIEAAKHKQYVLQQDEIPKLREQAKSTGNQMDVQAASDMEQFVDRLDKRIYDLQLSRQIAIQTAPQIRMIQNVNQALAEKIQSSILTSIPLWKNQMSIALTLMRQRNAVSAQKAVTDTTNDLLLKNSELLKQNALATTTENERGVVDIETLKTTQKDIIETIEQTLQIQEHGRTKRKQAESELNELETELQNQLLDMKENK
>NZ_CP054434.1|WP_011303124.1|1429756_1431388_+|BCCT-family-transporter
MKKKTRNIEESNNIKYSQWKEKLDWPVFLISGGILVLFVLMSSIFTKTTSTLVQKGFQLSITYFGAFWQVLLLATFAVGAFLAFSKYGRVRLGNASKPEMGYFRWAAIVITSGLGAGAIFWAAAEPMYYFIDVPPTMDPNIKNSSTQAIPAAMAQSFTSWGFTAWAVYGAVSGIIIMYAHYNKNMKMRPRTLLYPIFGSKIEKNKIGWMIDVFCILGAVAGTIGTIGFFGFQFSYWLHSIFGIPDNIITQILSVVGLMVVVTISATTGIDKGIQFLSKLNVWLALALAVFILLIGPGRFIIDTFISSYGVYLTHFLEISTFRGDDKWAGAWMLFFFGWFIGYGPLMGMLVARVSKGRTIREIFLLVSIVAAVVSHLWFSILGGSGLFYETKDSGAISNPLADNGLPAAVISIASHLPLGTALVIVLLLLTLIFVITTADTMSFSISMSVTGEGDPPKMIRLFWVVIMGVISIILINIGEGSINAIQSFIIITAVPISIIMLPAIWTAPKIAHKLAVEQKITTENKQDHTKDNILEERSSDNKH
>NZ_CP054434.1|WP_061050602.1|1428184_1429528_+|branched-chain-amino-acid-transport-system-II-carrier-protein
MNKNTWIIGFTLFAMFFGAGNLIFPPNLGFESGQYFWPSILAFALTGIGLPLLGVIVGALDKQGYIGSLNKISPKFSIIFLIIIYLTIGPLFAIPRTASTSFEMTVTPIANTNSNLALFIFTVIYFLIVLYLCINPSRMVDRIGSLLTPLLLITILAMIVKGFVDYGSNSHSQATDAFTSNFSGFSQGFTNGYLTMDAIAAIAFSMIVVNAVKATGVTHANKIFKQTLMAGIIAAVALMFIYISLGYIGNHMAVSQEKIASLTANDQNIGTYLLTTMASVGFGTFGKYLLGIIVALACLTTACGLVVAVSEYFHRIFPRISYKIYVIIFTLISFILANQGLNSVITMSVPVLSIVYPIAITSVLLILLARFVPTKPIAQQIPVAIVSIVSILSVIHTQGWIKLSFIDSLPLKSYSLEWFPIAIVTTIIGYIVAAMVKKQKPIVYEKE
>NZ_CP054434.1|WP_048787358.1|1426169_1428062_+|hypothetical-protein
MSDRFIKFNDEQLDAKQVMMLQDLARLLLKNDQTQVKIQKFPYYDPINNTLITSSFWSHRDIAIETTGLKTDVMLAAYGYQMMDEQIVNEVIHNTTFQHPKFFQQLFKLLEDQRILNAIARQRPSIQPAIQMRKEVRLNYTKTQIKVYKTKTTFTDLLFLHLEASFITENFYDIPQIHPHIDDILNNMYMYLHNFFYNQSSEDNMYLAERIMYQIDDILKEDMLNEYYHLPKKVYEAIEALKFEDLTRTDASNSDGKSEEQSDDNTVSEDMESNHQDSASQGGAYLEMELHEGENSEVMGDNDNAREGDASDDMTDMQTKKGNGLTNNQIDDDEGGSVGHNQAFALKGINERVEIKWNIPDIEPQYVQAYKNVESDVQFEIKGLIQIIQKTIDREHVDERHNLTKGRLQKNLLNWFIDDQYKLFYKKQDLSQSFDATFTLLIDASASMQDKMEETIKGVVLFHETLKSLNVKHEILAFNEDAFDADDANQPNIIDEIISYDHSTLEKDGPRIMALEPQDDNRDGVAIRVGSERLMRRSHNQRFLIVFSDGEPSAYNYSQDGILDTYEAVEMSRKMGIEVFNVFLSQEPITEDIEQTIHNIYGQYALFVEGVENLPAQLSPLLKKLLLKSF
>NZ_CP054434.1|WP_002483311.1|1425365_1426157_+|MoxR-family-ATPase
MANTNYINRDETVFNDAQSLMQLNKNILLKGPTGSGKTKLAETLSETMNRPMHQINCSVDLDAESLLGFKTIQTNENGSQEIVFIDGPVIKAMKEGHILYIDEINMAKPETLPILNGVLDYRRKLTNPFTGEVVNAAPGFNVIAAINVGYIGTLPMNEALKNRFVVIQVDYIDGDILSDVIKQQSQLSDDIMIQKIIKFNEDLRTMTKQGQISEEAASIRALIDLSDLATIMPIERAIQRTIIDKLEDEREQQAILNAVELNF
>NZ_CP054434.1|WP_047503768.1|1425008_1425212_+|hypothetical-protein
MLHETWKNNTPIKKVEVVHTDAQKFTVSDMLTIDKQYDVINETEEYYQIVDNSGLVGGYYKDYFKEV
>NZ_CP054434.1|WP_047503752.1|1434827_1436093_-|diaminopimelate-decarboxylase
MVVEYNSNGELTMGGTSLKTIAQSFGTPTFVYDEVQIRNQMRRYHEAFKQSGLAYNISYASKAFTCLQMVKLVQEEGLELDVVSEGELYTALEAGFDPKHIHFHGNNKTKHEIQYALESKVGYIVIDSLEEIDLIERYASEEIDVVLRLNPGVEAHTHEFIQTGQEDSKFGLSIKHGLAIQGIEKVRDTQKLNLKGVHFHVGSQIEGTEAMIETANIVINWLKANDIKVDLINLGGGFSIKYVEGDVSFPIEEGIAEITAAIKSIAEDADYPVPEIGIEPGRSIVGEAGITLYEVGTIKEIPQVNKYVSIDGGMSDHIRTALYDAKYEALLVNRNDPKDETVTIAGKLCESGDIIIKDAQLPSTVKRGDYLAILSTGAYHYSMASNYNQMQKPSVFFLKDGKAREVIKRQSLRQLIINDTK
>NZ_CP054434.1|WP_011303130.1|1436096_1437170_-|alanine-racemase
MTATWSVNRQLFKENAKNVKQDNQIMAVVKNNAYHYGLEFAVEQFLDIGINTFSTTSLKEAIRIRKLAPNATIFLMNAVYEFDKIRENQIQMTLPSLSFYYENINDLYDIQVHLEYENLLHRSGLKTLDEIKEVIHHHNQNKNEHKMHISGLWTHFGYADEFDVPDYNIERAAWLEIVDTLLDEGYEFEMIHAQNSASYYREQGVLPNHTHARIGIALYGSRPYSTINESDIQQSLTVKGNVIQVREVNAGEFCGYSFAFEATKNNTKLAVVDVGYGDGILKARAQHEALINHKRYPIRALMMSHMFVEVDDSVNAQDEVILYNNHIRVDEFTFKGVGANSEQLSAMNHDSLIKEYR
>NZ_CP054434.1|WP_048787356.1|1437166_1438324_-|amidohydrolase
MTELEFVTEHRRYLHKHPELSLHEYETTKYIAHFLDDLGVPYERPLDTGVIAYLSGNSTHTIAYRADIDALPIYEENNVSYRSEVDHVMHACGHDGHTTALMLFVKRCKNLADKGELPQNIVFIFQPAEETGGGANRLIRAGAFEKYPIEAVFGIHVMPFENEGRVVIRDEEITASATEYRFYLHGLSSHVADKEQGHSCGEALQHVLTQVGQIQQYHLNGLKRNIVHMGHFEAGEAINTVPSNGYLEGTIRTYDVKDLEIVKQQMTKISESVKLLFNVECEVKFEEGYPPTFNDPQLRKHVENGLVNAEFEVIDKPTPYLFGEDFSFYSQIAPSYFVFVGVRDEPKGYVTGLHTSHLNFNESILIRIADYYEQILKSYSEVQSQ
>NZ_CP054434.1|WP_047503746.1|1438613_1439333_-|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-acetyltransferase
MVQHLTAEEIIQYISDAKKSTPLKVYINGDFENITFPSDFKVFGSSDSKVIFCEADDWKPFYESNQSVIDEIEVEMDRRNSAIPLKDLTNTNARIEPGAFIREQAIIEDGAVIMMGATINIGAVVGEGTMVDMNATLGGRATTGKNVHVGAGSVLAGVIEPPSASPVVIEDDVLIGANAVILEGVCVGAGAIVAAGAIVTQDVPAGAVVAGTPAKVIKQTTEVEDSKREIVSALRKLND
>NZ_CP054434.1|WP_048787355.1|1439355_1440078_-|4-hydroxy-tetrahydrodipicolinate-reductase
MKILLIGYGAMNQRVARLAEEKNHEIVGVIVRNSEKHYPYPTFEHISEATEADVAIDFSNPELLLPLLEEDFNLPVVIATTGEKEQIIDKLKALSTDMPVFFSANMSYGVHALTKILEAAVPLLQDFDIELTEAHHNKKVDAPSGTLVKLYDVIESLRETTTPVYDRHETTEKRTQDEIGIHSIRGGTIVGEHDVVFAGTDETIEITHRAQSKDIFANGAIGAAEKLVQNKNGYYTFDNL
>NZ_CP054434.1|WP_011303134.1|1440074_1440962_-|4-hydroxy-tetrahydrodipicolinate-synthase
MGHIFEGVGVALATPFTHNEVDFDALRRHVKYLLDNNAKSIVVNGTTAENPTLTDEEKDQILEVVVNVVDGRVPVIAGTGTNNTQKSIQASVRAREIGADAIMLITPYYNKTNQRGLIAHFTTIADAVKLPVVLYNVPSRTNMTIDAETVETLSENEYIVALKDATNDFDYLEDLKQRLNLDEFALYSGNDDNIVDYFNQGGHGVISVVANVIPNAFQSLYDAKQNDENIQSQFQPIQTLLDALAVDVNPIPVKALTAVEGFGNYEVRLPLVTLEDSDRQKLEQAYEQFKVGGNS
>NZ_CP054434.1|WP_011303135.1|1440963_1441953_-|aspartate-semialdehyde-dehydrogenase
MTRLAIAGATGLVGRKMLETVDRKGIVFDELVLFSSARSAGEQIEFQGKTYTVRELTDEAASEPFDYVLMSAGGSTSEHYSPIFEQAGAIVIDNSSQWRMTEGIDLIVPEVNEPKLDRKIIANPNCSTIQSVVPLKPLQEAFGLKRVAYTTYQAVSGSGVKGKQDLAEGANGKAPEAYPHSIYNNVLPHIDTFLEDGYTKEEQKMIDETRKILQDDHLKVTATCVRVPVQDSHSVHMSVTLEKEATVSAIQELFEKDDRVVLVDNPQNNEYPLAIHSTGRDEIFVGRIRRDDSLDNTFHVWCTSDNLLKGAALNAVQILEQVMSLKGVK
>NZ_CP054434.1|WP_011303136.1|1442003_1443212_-|aspartate-kinase
MNLERSVLKFGGSSVSDFTKIKNIAEMLSLRIAQGEQLIVVVSAMGKTTDELMANVSTLTTSPKDQELALLLTTGEQQTVSYLSMVLNDIGVRAKAMTGYQAGIKTVGHHLKSRIAEINPETFEQAFEENDVLVVAGFQGINDDLEVTTLGRGGSDTTAVALAASNHTPCEIYTDVDGVYATDPRLYKDAKRLDYVSYEEMMEMSALGAGVLETRSVELANNYNIPLYLGRTLSNVKGTWIMPQTEILEKKAVTGVALDTHMMHVTISYPLPDNKLLTKLFSQLEDGSVNVDMISQIVNLEGLQMSFTIKDTDVAQISSILETLKEDFSALDFRINEEYVKISLIGSGMRDMSGVASKAFITLIENDISFYQTTTSEISISCVIDAENGERAVQTLYQAFDI
>NZ_CP054434.1|WP_011303137.1|1443652_1444483_-|aldo/keto-reductase
MKNLNMIDGQVLPQIGFGTYKLNGAHGAHAITNALNQGYRLLDTAYNYENEGTVGKAIDNSHVTRDQVIITSKLPGRYQDYDAAMVAIQESIYRLGVEYLDLYLIHWPNPKQGKYVEAWQAMIDAQKAGLIKSIGVCNFLPEHIETLEKETGVLPVVNQIELHPYFNQQDMIEYHNQKGIITQAWSPLGRASEVIKDKDVAVIAEKYNKTIPQIILKWHVQNGVVPIPKSTSIARQIQNKDIFDFTLEQQDIDKINSLTQQDGRLKGQDPASYEEF
>NZ_CP054434.1|WP_002483328.1|1444699_1446304_-|ATP-binding-cassette-domain-containing-protein
MLQVTDVSLRFGDRKLFEDVNIKFTDGNCYGLIGANGAGKSTFLKILSGELDAQTGHVSMGKNERLAVLKQDHFAFEDERVIDVVIKGHERLYAVMKEKDEIYMKPDFSDEDGIRAAELEGEFAEMDGWNAEADAGSLLSGLGIKADLQDKTMSELENNQKVKVLLAQSLFGKPDVLLLDEPTNGLDIPAISWLEDFLINFENTVIVVSHDRHFLNNVCTHIADLDYGKIKVYVGNYDFWYQSSELAMKMAQDQNKKKEEKIKELQDFVARFSANASKSKQATSRKKQLEKIELDDIQPSSRRYPFVKFTPEREIGNDLLFVENLSKTIDGVKVLDNISFTMDPNDKAVLIGDSEFAKSTLLKILAGEMEPDEGSVRWGVTTSRSYFPKDNSDYFEGVDMNLVDWLRQYAPEDEQTETFLRGFLGRMLFSGEEVKKKASVLSGGEKVRCMLSKMMLSSANVLLLDEPTNHLDLESITAVNDGLKNFKGSIIFTSYDFEFINTIANRVIDLNPAGAVSKEISYEAYLEETGVLAK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1048054 : 1062281

Staphylococcus_phage(92.31%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041784790.1\|1048054_1049437_+	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	5.3e-167	61.3
WP_011302825.1\|1049456_1050461_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	2.9e-90	49.4
WP_011302826.1\|1050450_1050702_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	4.2e-30	81.1
WP_011302827.1\|1050761_1051238_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	4.8e-43	53.5
WP_172439364.1\|1051221_1052013_+	prolyl oligopeptidase family serine peptidase	A0A2H4PQM6	Staphylococcus_phage	4.2e-100	71.4
WP_011302829.1\|1052108_1053698_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	8.5e-262	81.8
WP_011302830.1\|1054086_1055283_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.8e-195	86.6
WP_011302831.1\|1055381_1056290_+	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	1.1e-101	75.8
WP_011302832.1\|1056459_1057296_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	4.2e-111	68.2
WP_047504130.1\|1057566_1057923_-	CrcB family protein	NA	NA	NA	NA
WP_011302834.1\|1057919_1058285_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.3e-36	62.8
WP_011302835.1\|1058495_1058801_-	hypothetical protein	NA	NA	NA	NA
WP_011302836.1\|1059085_1059799_+	transaldolase	E3SKN5	Synechococcus_phage	2.9e-20	36.3
WP_011302838.1\|1060914_1061364_+	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	1.3e-21	47.5
WP_011302839.1\|1061371_1061797_-	competence protein ComK	NA	NA	NA	NA
WP_048787400.1\|1061810_1062281_-	sigma-70 family RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	2.2e-24	44.4

DBSCAN-SWA_2

1066727 : 1083815

Staphylococcus_phage(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048787170.1\|1066727_1068194_+	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	5.5e-13	58.6
WP_011302848.1\|1068735_1069779_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.0e-130	64.4
WP_011302849.1\|1069785_1070418_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	5.0e-72	64.8
WP_011302850.1\|1070429_1071611_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	4.2e-165	71.2
WP_002482978.1\|1071624_1072083_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	6.6e-58	76.3
WP_047504116.1\|1072347_1073349_-	proline dehydrogenase family protein	A0A2H4PQT6	Staphylococcus_phage	7.3e-126	68.5
WP_011302852.1\|1073615_1074440_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_011302853.1\|1074675_1075632_+	L-lactate dehydrogenase	NA	NA	NA	NA
WP_002482982.1\|1075783_1076185_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_011302854.1\|1076303_1076864_-	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	9.5e-67	63.8
WP_011302855.1\|1076860_1077814_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	7.3e-67	83.3
WP_011302856.1\|1077923_1079093_+	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	2.0e-167	77.4
WP_011302857.1\|1079621_1082036_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	85.6
WP_002482987.1\|1082054_1082366_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	4.5e-34	68.9
WP_011302858.1\|1082546_1083815_-	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	1.5e-38	77.2

DBSCAN-SWA_3

1205582 : 1214707

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047503974.1\|1205582_1206587_+	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.9
WP_047503971.1\|1206589_1207615_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_011302950.1\|1207635_1208781_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	2.5e-85	45.0
WP_011302951.1\|1208796_1209057_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	7.4e-06	44.1
WP_047503968.1\|1209438_1211715_+	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.7e-29	34.6
WP_174538726.1\|1211896_1214176_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	3.8e-69	29.4
WP_002483102.1\|1214188_1214707_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	6.6e-30	46.2

DBSCAN-SWA_4

1341008 : 1350975

uncultured_Mediterranean_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002483230.1\|1341008_1341896_+	site-specific tyrosine recombinase XerD	A0A0K2CP59	Brevibacillus_phage	5.1e-38	31.4
WP_011303058.1\|1341963_1342470_-	DUF309 domain-containing protein	NA	NA	NA	NA
WP_011303059.1\|1342561_1343296_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	1.4e-09	23.5
WP_047503875.1\|1343279_1343828_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	1.6e-10	31.4
WP_002483234.1\|1343820_1344558_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_011303060.1\|1344684_1345410_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.1e-46	42.6
WP_174538820.1\|1345390_1347157_+	HAMP domain-containing protein	A0A1V0SGX0	Hokovirus	1.7e-21	23.8
WP_037538408.1\|1347584_1348130_+	ECF transporter S component	NA	NA	NA	NA
WP_002483238.1\|1348285_1348534_-	ferredoxin	A0A127AYY7	Bacillus_phage	4.9e-15	48.0
WP_069822462.1\|1348643_1349603_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_064205480.1\|1349595_1350975_+	ATP-dependent DNA helicase RecQ	M1PGQ0	Moumouvirus	7.1e-55	32.4

DBSCAN-SWA_5

1680616 : 1772496

102

Staphylococcus_phage(41.51%)

head,tail,plate,terminase,integrase,holin,portal,transposase,tRNA

attL 1711808:1711829|attR 1753972:1753993

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011303319.1\|1680616_1683367_-\|tRNA	isoleucine--tRNA ligase	A0A1V0SJ93	Klosneuvirus	2.0e-88	27.8
WP_011303320.1\|1683609_1684212_-	DivIVA domain-containing protein	NA	NA	NA	NA
WP_104010417.1\|1684351_1685131_-	RNA-binding protein	NA	NA	NA	NA
WP_002483537.1\|1685238_1685529_-	YggT family protein	NA	NA	NA	NA
WP_047503516.1\|1685542_1686148_-	cell division protein SepF	NA	NA	NA	NA
WP_011303322.1\|1686153_1686828_-	YggS family pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_047503513.1\|1686845_1687634_-	peptidoglycan editing factor PgeF	NA	NA	NA	NA
WP_002483541.1\|1688080_1689253_-	cell division protein FtsZ	NA	NA	NA	NA
WP_047503508.1\|1689282_1690713_-	cell division protein FtsA	NA	NA	NA	NA
WP_052190972.1\|1690818_1691706_-	FtsQ-type POTRA domain-containing protein	NA	NA	NA	NA
WP_174538745.1\|1691721_1693071_-	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	NA	NA	NA	NA
WP_011303326.1\|1693072_1694038_-	phospho-N-acetylmuramoyl-pentapeptide- transferase	NA	NA	NA	NA
WP_174538746.1\|1694231_1696466_-	penicillin-binding protein	NA	NA	NA	NA
WP_011303328.1\|1696446_1696839_-	cell division protein FtsL	NA	NA	NA	NA
WP_011303329.1\|1696853_1697789_-	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	NA	NA	NA	NA
WP_011303330.1\|1697803_1698235_-	division/cell wall cluster transcriptional repressor MraZ	NA	NA	NA	NA
WP_048787295.1\|1698384_1699998_-	bacillithiol biosynthesis cysteine-adding enzyme BshC	NA	NA	NA	NA
WP_047503500.1\|1700260_1700701_+	N-acetyltransferase	NA	NA	NA	NA
WP_011303333.1\|1700815_1701499_-	noncanonical pyrimidine nucleotidase, YjjG family	NA	NA	NA	NA
WP_011303334.1\|1701638_1701773_-	beta-class phenol-soluble modulin	NA	NA	NA	NA
WP_048787296.1\|1701811_1701946_-	beta-class phenol-soluble modulin	NA	NA	NA	NA
WP_048787297.1\|1702562_1704446_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_011303339.1\|1705606_1706230_+	LysE family translocator	NA	NA	NA	NA
WP_103314661.1\|1706788_1709146_-	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	6.2e-160	44.9
WP_011303341.1\|1709338_1709653_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_081229140.1\|1709793_1710702_-\|transposase	IS3 family transposase	A0A0C5AEA5	Paenibacillus_phage	3.6e-47	43.5
WP_011303343.1\|1710662_1711346_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_115340783.1\|1711429_1711507_-	hypothetical protein	NA	NA	NA	NA
1711808:1711829	attL	NA	NA	NA	NA
WP_047503486.1\|1712582_1712993_-	YolD-like family protein	A0A2H4JEH6	uncultured_Caudovirales_phage	2.0e-69	91.9
WP_011303347.1\|1713002_1713194_-	hypothetical protein	A0A2H4JGI3	uncultured_Caudovirales_phage	7.0e-30	95.2
WP_047503483.1\|1713289_1713538_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_107523634.1\|1713726_1714140_-	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_061050616.1\|1714129_1714639_-	DUF4065 domain-containing protein	A8ATC0	Listeria_phage	6.0e-44	53.7
WP_174538821.1\|1715031_1715979_-	N-acetylmuramoyl-L-alanine amidase	A0A1P8CMK9	Staphylococcus_phage	1.2e-85	53.0
WP_041080397.1\|1716406_1716664_-\|holin	phage holin	A0A2I6PF56	Staphylococcus_phage	1.7e-10	51.9
WP_104013924.1\|1716717_1716816_+	hypothetical protein	NA	NA	NA	NA
WP_041080395.1\|1717064_1717352_-	hypothetical protein	NA	NA	NA	NA
WP_174538747.1\|1717386_1719273_-	glucosaminidase domain-containing protein	B7T0E8	Staphylococcus_virus	3.1e-194	53.6
WP_174538748.1\|1719328_1719661_-	DUF2977 domain-containing protein	NA	NA	NA	NA
WP_174538749.1\|1719660_1721526_-\|plate	BppU family phage baseplate upper protein	A0EWU3	Staphylococcus_virus	1.0e-125	40.1
WP_174538750.1\|1721525_1723433_-	hypothetical protein	A0A059T5B2	Staphylococcus_phage	5.9e-209	58.4
WP_174538751.1\|1723447_1725304_-\|tail	phage tail protein	Q4ZC57	Staphylococcus_virus	6.0e-182	53.4
WP_174538752.1\|1725314_1726241_-\|tail	phage tail family protein	Q4ZC58	Staphylococcus_virus	2.1e-79	51.3
WP_174538753.1\|1726252_1729342_-\|terminase	terminase	Q4ZCD8	Staphylococcus_virus	1.5e-158	56.5
WP_061050623.1\|1729344_1729653_-	hypothetical protein	A0A2H4JC15	uncultured_Caudovirales_phage	1.1e-27	62.7
WP_061050624.1\|1729715_1730210_-	hypothetical protein	A0A2H4JI48	uncultured_Caudovirales_phage	1.1e-61	72.0
WP_061050625.1\|1730262_1730808_-	hypothetical protein	A0A1W6JPA3	Staphylococcus_phage	1.0e-73	80.8
WP_174538754.1\|1730813_1731236_-	DUF3168 domain-containing protein	A1BU61	Staphylococcus_virus	1.2e-45	64.4
WP_174538755.1\|1731596_1732304_-	hypothetical protein	W5RA17	Staphylococcus_phage	5.3e-38	42.1
WP_174538756.1\|1732372_1732663_-	HK97 gp10 family phage protein	A0A0N9BAY5	Staphylococcus_phage	1.7e-30	75.3
WP_174538757.1\|1732649_1732985_-\|head,tail	phage head-tail adapter protein	Q4ZCE5	Staphylococcus_virus	2.3e-36	60.0
WP_061050629.1\|1732986_1733283_-\|head,tail	phage head-tail adapter protein	Q4ZC67	Staphylococcus_virus	4.9e-30	63.3
WP_061050630.1\|1733282_1733576_-	Rho termination factor N-terminal domain-containing protein	A0A1W6JQI6	Staphylococcus_phage	2.5e-26	65.3
WP_174538758.1\|1733589_1734522_-	sugar-binding protein	A0A1W6JPD7	Staphylococcus_phage	4.5e-138	78.6
WP_174538759.1\|1734534_1735059_-	phage scaffolding protein	Q4ZBR6	Staphylococcus_phage	1.0e-25	52.6
WP_174538760.1\|1735177_1735372_-	hypothetical protein	A0A059T624	Staphylococcus_phage	3.6e-05	41.3
WP_174538761.1\|1735371_1736328_-\|head	phage head morphogenesis protein	A0A2H4JC26	uncultured_Caudovirales_phage	1.6e-130	72.6
WP_174538762.1\|1736290_1737703_-\|portal	phage portal protein	Q4ZAA9	Staphylococcus_virus	4.0e-186	67.9
WP_174538763.1\|1737707_1738970_-\|terminase	PBSX family phage terminase large subunit	I6T7M4	Staphylococcus_virus	5.6e-224	88.8
WP_174538764.1\|1738956_1739448_-\|terminase	terminase small subunit	Q4ZAI5	Staphylococcus_virus	6.2e-54	68.7
WP_174538765.1\|1739527_1739809_-	hypothetical protein	NA	NA	NA	NA
WP_174538766.1\|1740070_1740493_-	DUF1492 domain-containing protein	A0A0F6N3E5	Staphylococcus_phage	5.0e-60	82.0
WP_174538767.1\|1740507_1740651_-	hypothetical protein	NA	NA	NA	NA
WP_174538768.1\|1740650_1740947_-	DUF5052 family protein	S4UCP8	Listeria_phage	5.4e-29	65.3
WP_174538769.1\|1741011_1741707_+	DUF4145 domain-containing protein	U3PE05	Staphylococcus_phage	4.2e-64	53.4
WP_174538770.1\|1741688_1741871_-	hypothetical protein	U3PJ54	Staphylococcus_phage	1.4e-19	78.3
WP_174538771.1\|1741871_1742183_-	hypothetical protein	NA	NA	NA	NA
WP_164972241.1\|1742184_1742547_-	hypothetical protein	Q4ZC91	Staphylococcus_virus	7.9e-06	31.0
WP_041080365.1\|1742546_1742732_-	hypothetical protein	NA	NA	NA	NA
WP_061050641.1\|1742744_1742951_-	hypothetical protein	A0A1W6JPS2	Staphylococcus_phage	2.3e-10	47.8
WP_174538772.1\|1742928_1743129_-	hypothetical protein	NA	NA	NA	NA
WP_174538822.1\|1743125_1743929_-	ATP-binding protein	A0A2I6PDV5	Staphylococcus_phage	1.0e-61	46.2
WP_174538773.1\|1744026_1744878_-	DnaD domain protein	A0A1Q1PVU4	Staphylococcus_phage	7.2e-50	43.7
WP_061050645.1\|1744919_1745735_-	recombinase RecT	S6AVW6	Thermus_phage	2.1e-59	48.9
WP_174538823.1\|1745746_1746658_-	YqaJ viral recombinase family protein	A6XMH8	Bacillus_virus	2.3e-78	50.5
WP_061050646.1\|1746702_1747002_-	hypothetical protein	NA	NA	NA	NA
WP_061050647.1\|1747076_1747256_-	hypothetical protein	NA	NA	NA	NA
WP_061050648.1\|1747261_1747567_-	DUF771 domain-containing protein	Q4ZD49	Staphylococcus_phage	8.4e-17	45.5
WP_174538774.1\|1747767_1748136_+	hypothetical protein	NA	NA	NA	NA
WP_174538824.1\|1748504_1748723_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_174538775.1\|1748907_1749666_+	helix-turn-helix domain-containing protein	Q8SDX2	Staphylococcus_phage	5.3e-44	40.1
WP_174538776.1\|1749829_1750330_+	PH domain-containing protein	A0A0D4DCT6	Staphylococcus_phage	1.2e-55	66.7
WP_174538825.1\|1750668_1751715_+	thermonuclease family protein	A0A1P8CWK6	Bacillus_phage	3.0e-45	57.3
WP_174538777.1\|1751784_1752222_+	DUF4231 domain-containing protein	A0A1J0MFR0	Staphylococcus_phage	4.4e-67	88.3
WP_174538778.1\|1752215_1752623_+	TIR domain-containing protein	A0A2H4J496	uncultured_Caudovirales_phage	2.4e-59	80.0
WP_081224922.1\|1752619_1752817_-	hypothetical protein	A0A2H4JBN9	uncultured_Caudovirales_phage	8.9e-28	90.8
WP_174538779.1\|1752914_1753958_+\|integrase	tyrosine-type recombinase/integrase	A0A0D4DCG3	Staphylococcus_phage	4.0e-119	63.4
WP_048787032.1\|1754452_1754962_-	metallophosphoesterase	NA	NA	NA	NA
1753972:1753993	attR	NA	NA	NA	NA
WP_011303379.1\|1754958_1755543_-	XTP/dITP diphosphatase	A0A0P0A2M4	Ugandan_cassava_brown_streak_virus	5.2e-15	30.5
WP_047503109.1\|1755545_1756355_-	glutamate racemase	NA	NA	NA	NA
WP_002483630.1\|1756564_1757386_-	succinate dehydrogenase iron-sulfur subunit	NA	NA	NA	NA
WP_048787031.1\|1757388_1759152_-	succinate dehydrogenase flavoprotein subunit	NA	NA	NA	NA
WP_011303381.1\|1759196_1759808_-	succinate dehydrogenase cytochrome b558 subunit	NA	NA	NA	NA
WP_069793621.1\|1760136_1761924_-	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_011303383.1\|1762129_1762444_-	thioredoxin	A0A1X9I9P5	Staphylococcus_phage	6.6e-25	47.6
WP_011303384.1\|1762525_1764874_-	endonuclease MutS2	F2QAF8	Phaeocystis_pouchetii_virus	3.0e-13	24.9
WP_069793622.1\|1764883_1766596_-	DNA polymerase/3'-5' exonuclease PolX	A0A2H4UV14	Bodo_saltans_virus	1.7e-18	26.8
WP_047503103.1\|1766707_1767229_-	CvpA family protein	NA	NA	NA	NA
WP_002483638.1\|1767225_1767495_-	cell division protein ZapA	NA	NA	NA	NA
WP_048787030.1\|1767803_1768736_+	ribonuclease HIII	NA	NA	NA	NA
WP_047503101.1\|1769035_1771438_-\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_002483641.1\|1771437_1772496_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2I2L4E3	Orpheovirus	1.9e-31	37.9

DBSCAN-SWA_6

2083131 : 2101867

uncultured_Caudovirales_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011303647.1\|2083131_2084100_-	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	2.6e-136	78.3
WP_002483928.1\|2084513_2085482_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	2.2e-175	94.4
WP_048787330.1\|2085605_2087711_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	90.0
WP_002483930.1\|2087673_2088072_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	8.6e-54	76.5
WP_011303649.1\|2088798_2089686_+	DMT family transporter	NA	NA	NA	NA
WP_002483932.1\|2089699_2090200_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	2.0e-52	72.3
WP_048787329.1\|2090382_2091897_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	3.3e-69	35.8
WP_011303651.1\|2092267_2093773_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	6.3e-65	32.2
WP_011303653.1\|2094244_2095192_+	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	1.5e-11	23.6
WP_002483937.1\|2095362_2095911_-	5'-3'-deoxyribonucleotidase	A0A0A0PKY7	Bacillus_phage	2.0e-29	39.0
WP_174538790.1\|2096088_2097144_-	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	3.9e-21	27.2
WP_002483939.1\|2097302_2098820_-	ABC transporter permease/substrate-binding protein	NA	NA	NA	NA
WP_048787328.1\|2098816_2099779_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.8e-26	32.5
WP_047502733.1\|2100088_2101867_-	DNA helicase RecQ	K7YHB4	Megavirus	2.2e-77	36.4

DBSCAN-SWA_7

2110170 : 2117720

Pandoravirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011303663.1\|2110170_2111313_-	aminodeoxychorismate synthase component I	S4VNU7	Pandoravirus	5.4e-24	36.7
WP_011303664.1\|2111296_2111890_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.9e-36	41.5
WP_002483950.1\|2112145_2112817_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	1.2e-63	54.9
WP_011303665.1\|2112818_2113244_+	6-carboxytetrahydropterin synthase QueD	NA	NA	NA	NA
WP_002483952.1\|2113236_2113953_+	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	2.5e-51	43.4
WP_011303666.1\|2114193_2114787_+	hypothetical protein	NA	NA	NA	NA
WP_002483954.1\|2114855_2115107_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_011303667.1\|2115324_2116386_-	glycosyltransferase family 2 protein	A0A192Y8W7	Salmonella_phage	8.7e-61	42.3
WP_002483956.1\|2116880_2117720_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.2e-52	40.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP054434

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection