CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP040883	Staphylococcus epidermidis strain O47 chromosome, complete genome	4 crisprs	csa3,WYL,DEDDh,cas3,DinG	1	2	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP040883_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040883_1

446430-446513

Orphan

Consensus_repeat	Method
GAAATTCTACGGACAAGGCAAGTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040883_1

>merge|NZ_CP040883|1|446430-446513|CRISPRCasFinder
GAAATTCTACGGACAAGGCAAGTTGGGGTTCGGGGCCCCAACAAAGAGAATTTCACCGAGAAATTCCACGGACAAGGCAAGTTG

>NZ_CP040883|1|1|446430-446513|CRISPRCasFinder
GAAATTCTACGGACAAGGCAAGTTG	GGGTTCGGGGCCCCAACAAAGAGAATTTCACCGA
GAAATTCCACGGACAAGGCAAGTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040883.1\|WP_001831506.1\|458037_458805_-\|thiazole-synthase	unknown	unknown	gnl\|CDD\|234687
NZ_CP040883.1\|WP_001831584.1\|456315_456930_-\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP040883.1\|WP_162139016.1\|438642_438780_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040883.1\|WP_001831616.1\|457037_458036_-\|thiazole-biosynthesis-adenylyltransferase-ThiF	unknown	unknown	gnl\|CDD\|274094
NZ_CP040883.1\|WP_002456688.1\|444253_445747_+\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143435
NZ_CP040883.1\|WP_001831599.1\|440023_440635_+\|class-A-sortase-SrtA	unknown	unknown	gnl\|CDD\|130148
NZ_CP040883.1\|WP_002484424.1\|441974_442967_-\|D-lactate-dehydrogenase	unknown	unknown	gnl\|CDD\|183550
NZ_CP040883.1\|WP_001831463.1\|439363_439858_-\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|224168
NZ_CP040883.1\|WP_001831461.1\|448073_449021_+\|zinc-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238499
NZ_CP040883.1\|WP_126534841.1\|437234_438413_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376773
NZ_CP040883.1\|WP_001832363.1\|435953_436853_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	unknown	unknown	gnl\|CDD\|129801
NZ_CP040883.1\|WP_002438139.1\|439123_439300_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040883.1\|WP_001831535.1\|447625_447907_-\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|379642
NZ_CP040883.1\|WP_002468280.1\|443213_443876_+\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380324
NZ_CP040883.1\|WP_002484434.1\|446575_447364_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|225312
NZ_CP040883.1\|WP_002484437.1\|450764_451814_-\|membrane-protein	unknown	unknown	gnl\|CDD\|226458
NZ_CP040883.1\|WP_001832881.1\|454177_456142_-\|fructose-1,6-bisphosphatase	unknown	unknown	gnl\|CDD\|226373
NZ_CP040883.1\|WP_001831423.1\|452161_453949_+\|sodium:proton-antiporter	unknown	unknown	gnl\|CDD\|223104
NZ_CP040883.1\|WP_001831422.1\|440978_441788_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|369792
NZ_CP040883.1\|WP_174168247.1\|449091_450516_-\|aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143407

Protein	Function_ID	Function_description	E-value
NZ_CP040883.1\|WP_001831506.1\|458037_458805_-\|thiazole-synthase	gnl\|CDD\|234687	PRK00208, thiG, thiazole synthase; Reviewed.	3.65912e-146
NZ_CP040883.1\|WP_001831584.1\|456315_456930_-\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	3.68558e-44
NZ_CP040883.1\|WP_174168247.1\|449091_450516_-\|aldehyde-dehydrogenase	gnl\|CDD\|143407	cd07088, ALDH_LactADH-AldA, Escherichia coli lactaldehyde dehydrogenase AldA-like. Lactaldehyde dehydrogenase from Escherichia coli (AldA, LactADH, EC=1.2.1.22), an NAD(+)-dependent enzyme involved in the metabolism of L-fucose and L-rhamnose, and other similar sequences are present in this CD.	0
NZ_CP040883.1\|WP_001831616.1\|457037_458036_-\|thiazole-biosynthesis-adenylyltransferase-ThiF	gnl\|CDD\|274094	TIGR02356, molybdopterin_biosynthesis_protein_moeB, thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily. Members of the HesA/MoeB/ThiF family of proteins (pfam00899) include a number of members encoded in the midst of thiamine biosynthetic operons. This mix of known and putative ThiF proteins shows a deep split in phylogenetic trees, with the Escherichia. coli ThiF and the E. coli MoeB proteins seemingly more closely related than E. coli ThiF and Campylobacter (for example) ThiF. This model represents the more widely distributed clade of ThiF proteins such found in E. coli. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	3.34753e-109
NZ_CP040883.1\|WP_002456688.1\|444253_445747_+\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143435	cd07117, ALDH_StaphAldA1, Uncharacterized Staphylococcus aureus AldA1 (SACOL0154) aldehyde dehydrogenase-like. Uncharacterized aldehyde dehydrogenase from Staphylococcus aureus (AldA1, locus SACOL0154) and other similar sequences are present in this CD.	0
NZ_CP040883.1\|WP_001831599.1\|440023_440635_+\|class-A-sortase-SrtA	gnl\|CDD\|130148	TIGR01076, Uncharacterized_protein_YhcS, LPXTG-site transpeptidase (sortase) family protein. This family includes Staphylococcus aureus sortase, a transpeptidase that attaches surface proteins by the Thr of an LPXTG motif to the cell wall. It also includes a protein required for correct assembly of an LPXTG-containing fimbrial protein, a set of homologous proteins from Streptococcus pneumoniae, in which LPXTG proteins are common. However, related proteins are found in Bacillus subtilis and Methanobacterium thermoautotrophicum, in which LPXTG-mediated cell wall attachment is not known. [Cell envelope, Other, Protein fate, Protein and peptide secretion and trafficking].	1.43034e-42
NZ_CP040883.1\|WP_002484424.1\|441974_442967_-\|D-lactate-dehydrogenase	gnl\|CDD\|183550	PRK12480, PRK12480, D-lactate dehydrogenase; Provisional.	0
NZ_CP040883.1\|WP_001831463.1\|439363_439858_-\|N-acetyltransferase	gnl\|CDD\|224168	COG1247, COG1247, Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane].	8.8583e-62
NZ_CP040883.1\|WP_001831461.1\|448073_449021_+\|zinc-ABC-transporter-substrate-binding-protein	gnl\|CDD\|238499	cd01017, AdcA, Metal binding protein AdcA. These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AdcA proteins belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. They are comprised of two globular subdomains connected by a long alpha helix and they bind their ligand in the cleft between these domains. In addition, many of these proteins have a low complexity region containing metal binding histidine-rich motif (repetitive HDH sequence).	1.52754e-112
NZ_CP040883.1\|WP_126534841.1\|437234_438413_+\|IS110-family-transposase	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	3.09501e-19
NZ_CP040883.1\|WP_001832363.1\|435953_436853_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	gnl\|CDD\|129801	TIGR00718, Probable_L-serine_dehydratase_alpha_chain, L-serine dehydratase, iron-sulfur-dependent, alpha subunit. This enzyme is also called serine deaminase. L-serine dehydratase converts serine into pyruvate in the gluconeogenesis pathway from serine. This model describes the alpha chain of an iron-sulfur-dependent L-serine dehydratase, found in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of alpha chains from the homologous region of single chain forms such as found in Escherichia coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	8.36299e-108
NZ_CP040883.1\|WP_002484437.1\|450764_451814_-\|membrane-protein	gnl\|CDD\|226458	COG3949, COG3949, Uncharacterized membrane protein [Function unknown].	9.57735e-87
NZ_CP040883.1\|WP_002468280.1\|443213_443876_+\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|380324	cd02149, NfsB-like, nitroreductase similar to Escherichia coli NfsB. NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family includes FRase I in Vibrio fischeri, wihich reduces FMN into FMNH2 as part of the bioluminescent reaction. The family also includes oxygen-insensitive nitroreductases that use NADH or NADPH as an electron donor in the ping pong bi bi mechanism. This type of nitroreductase can be used in cancer chemotherapy to activate a range of prodrugs.	5.61762e-76
NZ_CP040883.1\|WP_001831535.1\|447625_447907_-\|N-acetyltransferase	gnl\|CDD\|379642	pfam14542, Acetyltransf_CG, GCN5-related N-acetyl-transferase. This family of GCN5-related N-acetyl-transferases bind both CoA and acetyl-CoA. They are characterized by highly conserved glycine, a cysteine residue in the acetyl-CoA binding site near the acetyl group, their small size compared with other GNATs and a lack of of an obvious substrate-binding site. It is proposed that they transfer an acetyl group from acetyl-CoA to one or more unidentified aliphatic amines via an acetyl (cysteine) enzyme intermediate. The substrate might be another macromolecule.	1.79195e-31
NZ_CP040883.1\|WP_002484434.1\|446575_447364_-\|VOC-family-protein	gnl\|CDD\|225312	COG2514, COG2514, Predicted ring-cleavage extradiol dioxygenase [General function prediction only].	2.27772e-97
NZ_CP040883.1\|WP_001832881.1\|454177_456142_-\|fructose-1,6-bisphosphatase	gnl\|CDD\|226373	COG3855, Fbp, Uncharacterized protein conserved in bacteria [Carbohydrate transport and metabolism].	0
NZ_CP040883.1\|WP_001831423.1\|452161_453949_+\|sodium:proton-antiporter	gnl\|CDD\|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	1.72739e-43
NZ_CP040883.1\|WP_001831422.1\|440978_441788_+\|HAD-family-hydrolase	gnl\|CDD\|369792	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase. This family contains haloacid dehalogenase-like hydrolase enzymes.	2.03989e-48

>NZ_CP040883.1|WP_002456688.1|444253_445747_+|aldehyde-dehydrogenase-family-protein
MTNINVRNYIDESYGLFINNEFQASDSGETLTVSNPANGEDLAKVARAGKKDVDKAVQAAHDAFDSWSKISKEERADYLLEISRRIHEKTEHLATVESLQNGKPYRETSTIDVPQAANQFKYFASVLTTDEGSVNEIDQNTMSLVVNEPVGVVGAVVAWNFPILLASWKLGPALAAGNTVVIQPSSSTPLSLIELAKIFQEVLPKGVVNVLTGKGSESGDAIFHHEGVDKLSFTGSTDVGYGVAQAGAERIVPTTLELGGKSANIIFDDANLEQVIEGVQLGILFNQGEVCSAGSRLLVQSSIYNELLPKLKEAFENIKVGDPFDEDTKMSAQTGPEQLDKIESYIKIAEEDDKANILTGGHRITDNGLDKGYFFEPTIIEINDNKHQLAQEEIFGPVVVVEKFDDEQEAIEIANDSEYGLAGGIFTTDIHRALNVAKAMRTGRIWINTYNQIPAGAPFGGYKKSGIGREVYKDAIKNYQQVKNIFIDTSNQTKGLY
>NZ_CP040883.1|WP_002468280.1|443213_443876_+|NAD(P)H-dependent-oxidoreductase
MNQMNQTIIDAFHFRHATKEFDPTKKISDEDFNTILETGRLSPSSLGLEPWHFVVVQNKELREKLKAYSWGAQKQLDTASHFVLIFARKNVTAHTDYVQHLLRGVKKYEESTIPAVENKFDDFQESFHIADNERTLYDWASKQTYIALANMMTSAALLGIDSCPIEGFDLDKVTEILSDEGVLDTEQFGISVMVGFGYRAQEPKHGKVRQNEDDIISWIE
>NZ_CP040883.1|WP_002484424.1|441974_442967_-|D-lactate-dehydrogenase
MTKIMFFGTRAYEKDMALRWGKKNNIDVTTSKELLSVDTVDQLKDYDGVTTMQFGKLESEVYPKLESYGIKQIAQRTAGFDMYDLELAKKHGIIISNIPSYSPETIAEYSVSIALQLVRKFPTIEKRVQAHNFTWASPIMSRPVKNMTVAIIGTGRIGAATGKIYAGFGAKVVGYDAYPNHSLSFLEYKETVEDAIKDADIISLHVPANKDSFHLFDNNMFKKVKKGAVLVNAARGAVINTPDLIEAVNNGTLSGAAIDTYENEANYFTFDWSNQTIEDPILLELIRNENILVTPHIAFFSDEAVQNLVEGGLNAALSVINTGTCDTRLN
>NZ_CP040883.1|WP_001831422.1|440978_441788_+|HAD-family-hydrolase
MIKAIAVDMDGTFLDTNKQFDRNRFETIFKELIDKNIKFVAASGNQFAKLKSIFGDREMFFISENGAVIYKGNQLYNYRSFDQYIFQKVVNYLNLNQKINNLIICGVKSAYILKETSEAFKQDARTYYHQLIEIDSLQTLPDDDYVKIAFNINRQTHPDLDEKLALKFKEDIKLVSSGRDSIDVIMPNMTKGQALSRLLKEWQMPASHLMAFGDANNDKDMLELAEHSYVMANSEDKSLFNIARHVAPSNDEQGVLSTIENVVLGYSNK
>NZ_CP040883.1|WP_001831599.1|440023_440635_+|class-A-sortase-SrtA
MKQWMNRLITLIGVLLIILAIYLFSKPYIDNYLHEKDNDHKIENYDKKEKEQTKTSKSTPKIPSDKSKMAGYIEVPDAQIKEPVYPGPATPEQLNRGVSFAEGDESLNQQNISIAGHTFTDRSHYQFTNLKSAKIGSKVYFKTGNQTRKYKITKIRDVKPTEVKVLDEHPNKKNQLTLITCDDYNEETGVWETRKIFIATQIN
>NZ_CP040883.1|WP_001831463.1|439363_439858_-|N-acetyltransferase
MIRFARLEDLQDILTIYNDAILNTTAVYTYKPQQLDERLQWYQSKAKINEPIWVYEKEGKVVGFATYGSFRQWPAYLYTIEHSIYVHQQYRGLGIASQLLENLIRYAKEQSYRTIVAGIDASNMDSIALHKKFDFSHAGTIKNVGYKFGRWLDLSFYQYDLSDS
>NZ_CP040883.1|WP_002438139.1|439123_439300_+|hypothetical-protein
MLRLFLIFIAFIINTTITYLWTIEGTWPNLLFKSLSLSMIIVFMFYYIRFVIENKKED
>NZ_CP040883.1|WP_162139016.1|438642_438780_-|hypothetical-protein
MTQHTLPMESSVLIPTNNISRHVNDIAETIPDTEFDEFRHYRGLI
>NZ_CP040883.1|WP_126534841.1|437234_438413_+|IS110-family-transposase
MSKRSSVVAHYKNGKFQKEFFIQNNKNGYNYLLKYLNDLHHPQLIFESTGIYSRGMERFCCVNQINYIQMNPLEAKFKTSALRSWKTDQADAHKLACLGPTLKQTGNLPIHELIFFELRERVRFHLEIENEQNRLKFQILELLHQTFPGLERLFSSRYSIIALNIAEIFTHPDMVLDIDKDVLITHIFNSTDKGMSMDKATKYALQLRVIAQESYPNVDRHSFLVEKLRLLIQQLKQSIHHLKQLDDAMIQLAQQLDYFENIHSIPGIGKLSTAMIIGEIGDIKRFKSNKQLNTFVGIDIKRYQSGHTHCRDTINKRGNKKARKLLFWVIMNIIRGQHHYDNHVVDYYYKLRKQPNEKPHKTAIIACINRLLKTIHYLVMNHKLYDYQMSPH
>NZ_CP040883.1|WP_001832363.1|435953_436853_+|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha
MFDSIRETIDYSVENNISFADMMINDEMEREGKSREEVRDLMRQNLNVMREAVEKGTTGDGVESVTGYTGHDAAKLRDYNENNHALSGHEMIDAVKGAVATNEVNAAMGIICATPTAGSSGTIPGVIFKLEKTHNITEDQMIDFLFTSALFGRVVANNASVAGATGGCQAEVGSASAMAAAAAVSIFNGSPEQSGHAMALAISNLLGLVCDPVAGLVEIPCVMRNAIGSGNALISADLALAGVESQIPVDEVIGAMDRVGRNLPASLRETGLGGLAGTPTGEEIKRKIFGEADNMVKNK
>NZ_CP040883.1|WP_002484434.1|446575_447364_-|VOC-family-protein
MTNFHSIDATQVTNVTLNVKDLNKSTDFYSNVLGFSIEKQTNQQTVFNIGNLGYTLTLNELNNGRQPEFREAGLFHVAYLLPTRSDLADFLYHANNLNIAMGGGDHLVSEALYFTDPEGNGIEVYHDRPSEDWVWRDGFVKMDTLEVNVNDLMAQRSNEGWPEEGKIGHLHLKTHNLESAYEFYVEKLGFEHISNFPQALFMSTQKYHHHIATNTWQSNKIRTQNEQTYGLCHFDIYQPNANTTHVTSPEGFDITIHGNETK
>NZ_CP040883.1|WP_001831535.1|447625_447907_-|N-acetyltransferase
MAAEIKQGDHKFYVGNDENNPKAVITFKEVDNNEIDIDHTGVSDELGGQGLGKKLVNRVVEHARENNLKIIASCPFAKNVLEKDDHAQDVYLG
>NZ_CP040883.1|WP_001831461.1|448073_449021_+|zinc-ABC-transporter-substrate-binding-protein
MKKLIIVSIIILMLSGCSSFDHRKRESINDKNKMKVYTTVYAFQSLTQQIGGKYVDAQSIYPAGADLHSYEPTQKDMIDIAKSDLFVYSSHQLDPVAAKITNSMTNNSMKLALAEGLKQSDFIHSKDHDENHEHHSHHEESNQDPHVWLDPVLNQKFAFMIKEKLIEKDPKHQAYYNKNYKIVNKDIVHIDQQLQSITKHYKRDKVVISHDSLGYLAHRYGFKEQGVKGMNDEEPSQKEILNIVKDIQHSHAPYVLYEQNITSKITDVIKKETDTKPLSFHNLAVLTKEEQNDDSISYQSLMKKNIYVLNRALNN
>NZ_CP040883.1|WP_174168247.1|449091_450516_-|aldehyde-dehydrogenase
MTNQLFINNEFIESQSKETMDVINPSTGEAFDTITLATEEEVNDAIEKSQQAQLEWERVPQPTRAEHVKLLIPLLEKNRDQIAQLYVKEQGKTLAQAYGEIDKSISFIDYMTSLSMSDKGRVLQNSIANETIQIINKPIGVTAGIVPWNAPILVLMRKVIPAIVTGCSVVIKPSEETTLLTLRLAELFRASTIPAGLIQIVPGTGETVGTQLASHKDIQLISLTGSMRAGKSVYENAAQTVKKVNLELGGNAPVIVTSNADLDKAVNYIVTARINNAGQVCTCPERIFVHEDVHDDFLNKVTSKMKSLTVGDPFDENTDYGAIINQKQLDSIHEKVQDAIKNGATLMTGGHQLKRHGFFYAPTVLDNVRKDYNVFKDEIFGPVLAITTYRDFEQVIEDANDTNAGLSSYIFSENLTEVMTATERLKFGEVYANCEAEEVVNGYHAGWRESGLGGADGIHGFEEYYNTTVSYIRY
>NZ_CP040883.1|WP_002484437.1|450764_451814_-|membrane-protein
MSNVKESIIVAFAFVGVVVGAGFATGQEIFQFFTSHGIYSIGGIFITGLIITLGGIFVLNTGFRLRSQNHSESIRYYLHPTIAKLFDIILTVFLFSLAIIMTAGGASTINESFGLPFWLSSLILVILILLTLFLKFDRLIAVLGGVTPFLVAVVVMIAVYYFITGDLNFSDVSQYSNQNKSISPGWWFDAINYASLQIAAAFSFLTVMGGKLRYQSSTIYGGLIGGIIVTLLLLLINFGLVTEFNQIKEVALPSLLLAKQISPSIGIIMSVIMVLVIYNTVVGLMYAFASRFSRPFTKRYYILIVMMAIITFACTFVGFISLIGKVFPIMGLFGFILLIPVIYKGILRK
>NZ_CP040883.1|WP_001831423.1|452161_453949_+|sodium:proton-antiporter
MSLELPVMLTIVLFLALGIFSQWLASRIKWPSIVVMAIVGLLVGPIFGLANPKEALGPEAFSSIVSLAVAIILFEGSSNLDFRELKGISKAVIRIITIGAGIAWILGAIALHVTMNFPLSISFVIGGLFLITGPTVIQPLLKQAKVKRNVDSVLRWESIILDPIGPIIALTAFYVFQIFEEGIGFVVIILFILKLLAAILIGFGAAFLFNWLIGQDKIPQSLMPPIQFVFILLTFSICDEILSESGLLAVTIFGLMMARKKRHDLIFKESDHFIDNASSILVSTVFILITSSLTKDVLLNVLSWQLILFSLVMIVLVRPISVLLSTLGTEITKKERAVVALMAPRGIVVLTVAQFFSSLFMDDKIPMAQYITPVTFGLVFITVVIYGFGFTPLSKLFGVASTEPPGVIIVGESEFSFHLGINLRDHGIPVMMFNLFENTSEKAHEAGFEVFKGNLLSSNDRIYSDLLRYNKCILMTQSFIFNSLAFNELVPEFGLNNVDMMPVSFNDEQARNNLNGPIRNHILFDENHTPRWFNQFITQHNIVEVPAEDYEKITENDMLIYHINEDKEVTFKRSNRDIPEHETGVYGILKNAYLT
>NZ_CP040883.1|WP_001832881.1|454177_456142_-|fructose-1,6-bisphosphatase
MTHITESEMKQKYLDLLSQKFDSAEKLATEIINLESILELPKGTEHFVSDLHGEYESFQHVLRNGSGNVRAKINDIFKDKLSQQEINDLAALVYYPEEKLKLVKNNFDSIGTLNIWYITTIQRLIDLITYCSSKYTRSKLRKALPEQYVYIIEELLYKSNEFHNKKPYYETLVNQIIELEQSDDLIIGLSYTVQRLVVDHLHVVGDIYDRGPKPDKIMDTLINYHSVDIQWGNHDVLWIGAYAGSKVCLANLLRICARYDNLDIIEDAYGINLRPLLTLAEKYYDAENPAFKPKKRPDKDVSLTKREESQITKIHQAIAMIQFKLEMPIIKRRPSFEMEERLVLEKIDYDNNEITIYNKTYPLKDTCFQTVNPNNPAELLAEEKEVMDKLLLSFQQSEKLRRHMSFLMRKGKLYLPYNGNLLIHGCIPVDENGEMESFEIEGERLSGRELLDVFEYHVRKAFDHKESTEDISTDLVWYLWTGKYSSLFGKRAMTTFERYFIEDKASHKEEKNPYYYLREDVDMIRKMLKDFGLNPDEGRIINGHTPVKEIDGEDPIKANGKMLVIDGGFSKAYQSTTGIAGYTLLYNSFGMQLVAHKEFNRKEKVLSMGADELSVKRVVDEELQRKKIRDTNIGKQLQDQIDILKILMHDRYLT
>NZ_CP040883.1|WP_001831584.1|456315_456930_-|DedA-family-protein
MEQIITDFISKWGYTAIFILILLENVLPVVPSEIILTFAGLLSVKSHLSIWTLLIIATIASFIGLLILYYICRLISEEKLYRFVDRHGKWMKLKSKDLKRANDWFKKYGAWAVFLCRFVPVLRVLITIPAGINRMNVIQFTTLSLIGTTIWNFALILLGRLLSDSFDALMNGIHTYSRIMYVIIIIAVIYFVIRYLMKRRRSVK
>NZ_CP040883.1|WP_001831616.1|457037_458036_-|thiazole-biosynthesis-adenylyltransferase-ThiF
MSRYERQTRFAPFGEEGQQKLSSSQILIFGAGALGSHIVDQLARMGAHHIAIVDMDIVEISNLHRQTLFDEEDAHTLISKVEAIKHKVNQININVNLTTYDLEVTSSNIENLIKNVEPDIIIDGMDNFKIRYLINEVCHKYQIPWVYGAAVGSKGSVYGIDHQGPCLKCLLQTIPDTGESCAINGVIPPVISMIASYEVAEAVRYLSGKGFSKQLITIDAFNINYKSMNVDALKNKDCPVCEKHEYTLLESQQERTIEDLCGNAYLFRFPPKAFKHAAHFPGNMVKSTSFAKLIQYQTYEFTLFKDGRMNAYGIHNDEEAHHLYNTLLKSIR
>NZ_CP040883.1|WP_001831506.1|458037_458805_-|thiazole-synthase
MFKIGNLELQSRLLLGTGKFENEEVQSKAIEASETNVLTFAVRRMNLYDRNLPNPLANVNLKDFITFPNTAGAKTAQEAIRIAEIANHAGVCDMIKVEVIGDDETLLPDPFETYEACKVLLEKGYTVCPYISNDLVLAQRLEELGVHAVMPLASPIGTGRGINNPLNLSYIIENASVPVIVDAGIGSPKDACHAMELGADGILLNTAISAAKDPVKMAEAMKLGINAGRLSYEAGRIPVKYTAQASSPSEGLGFL

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Crispr_ID: NZ_CP040883_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040883_2

1722459-1722560

Unclear

Consensus_repeat	Method
CACTTAATACATAGGTATTTAGTGTTTTTTATACATGA	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NZ_CP040883_2

>merge|NZ_CP040883|2|1722459-1722560|CRISPRCasFinder
CACTTAATACATAGGTATTTAGTGTTTTTTATACATGAACCTCAAGCTCATGTGTTCCTCTTTTCACTTAATACATAGGTATTTAGTGTTTCTTATACATGA

>NZ_CP040883|2|2|1722459-1722560|CRISPRCasFinder
CACTTAATACATAGGTATTTAGTGTTTTTTATACATGA	ACCTCAAGCTCATGTGTTCCTCTTTT
CACTTAATACATAGGTATTTAGTGTTTCTTATACATGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040883.1\|WP_002456579.1\|1725951_1728000_-\|ATP-dependent-DNA-helicase-RecG	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|236794
NZ_CP040883.1\|WP_001830161.1\|1722598_1723333_-\|3-oxoacyl-[acyl-carrier-protein]-reductase	unknown	unknown	gnl\|CDD\|235500
NZ_CP040883.1\|WP_001830113.1\|1714634_1716002_-\|signal-recognition-particle-protein	unknown	unknown	gnl\|CDD\|236780
NZ_CP040883.1\|WP_001830164.1\|1730879_1731515_-\|thiamine-diphosphokinase	unknown	unknown	gnl\|CDD\|273588
NZ_CP040883.1\|WP_001830156.1\|1729876_1730251_-\|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl\|CDD\|224221
NZ_CP040883.1\|WP_001830184.1\|1722137_1722371_-\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|179197
NZ_CP040883.1\|WP_001832559.1\|1713421_1713925_-\|ribosome-maturation-factor-RimM	unknown	unknown	gnl\|CDD\|234650
NZ_CP040883.1\|WP_002439483.1\|1714051_1714327_-\|30S-ribosomal-protein-S16	unknown	unknown	gnl\|CDD\|223306
NZ_CP040883.1\|WP_001830099.1\|1725232_1725793_-\|transcription-factor-FapR	unknown	unknown	gnl\|CDD\|179847
NZ_CP040883.1\|WP_002469385.1\|1723325_1724252_-\|ACP-S-malonyltransferase	unknown	unknown	gnl\|CDD\|223408
NZ_CP040883.1\|WP_001830173.1\|1731519_1732164_-\|ribulose-phosphate-3-epimerase	unknown	unknown	gnl\|CDD\|238244
NZ_CP040883.1\|WP_002456575.1\|1721285_1722023_-\|ribonuclease-III	unknown	unknown	gnl\|CDD\|234633
NZ_CP040883.1\|WP_002469384.1\|1724253_1725231_-\|phosphate-acyltransferase-PlsX	unknown	unknown	gnl\|CDD\|235414
NZ_CP040883.1\|WP_002456573.1\|1716366_1717593_-\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
NZ_CP040883.1\|WP_001829466.1\|1712684_1713422_-\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	unknown	unknown	gnl\|CDD\|234581
NZ_CP040883.1\|WP_002484841.1\|1717589_1721159_-\|chromosome-segregation-protein-SMC	unknown	unknown	gnl\|CDD\|224117
NZ_CP040883.1\|WP_002457379.1\|1716032_1716365_-\|putative-DNA-binding-protein	unknown	unknown	gnl\|CDD\|234647
NZ_CP040883.1\|WP_002436293.1\|1712228_1712579_-\|50S-ribosomal-protein-L19	unknown	unknown	gnl\|CDD\|235418
NZ_CP040883.1\|WP_001830107.1\|1730608_1730797_+\|50S-ribosomal-protein-L28	unknown	unknown	gnl\|CDD\|234736
NZ_CP040883.1\|WP_002456580.1\|1728203_1729862_-\|DAK2-domain-containing-protein	unknown	unknown	gnl\|CDD\|274671

Protein	Function_ID	Function_description	E-value
NZ_CP040883.1\|WP_002456579.1\|1725951_1728000_-\|ATP-dependent-DNA-helicase-RecG	gnl\|CDD\|236794	PRK10917, PRK10917, ATP-dependent DNA helicase RecG; Provisional.	0
NZ_CP040883.1\|WP_001830161.1\|1722598_1723333_-\|3-oxoacyl-[acyl-carrier-protein]-reductase	gnl\|CDD\|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	8.64489e-139
NZ_CP040883.1\|WP_001830113.1\|1714634_1716002_-\|signal-recognition-particle-protein	gnl\|CDD\|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0
NZ_CP040883.1\|WP_001830164.1\|1730879_1731515_-\|thiamine-diphosphokinase	gnl\|CDD\|273588	TIGR01378, Thiamine_pyrophosphokinase, thiamine pyrophosphokinase. This model has been revised. Originally, it described strictly eukaryotic thiamine pyrophosphokinase. However, it is now expanded to include also homologous enzymes, apparently functionally equivalent, from species that rely on thiamine pyrophosphokinase rather than thiamine-monophosphate kinase (TIGR01379) to produce the active TPP cofactor. This includes the thiamine pyrophosphokinase from Bacillus subtilis, previously designated YloS. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	5.23977e-73
NZ_CP040883.1\|WP_001830156.1\|1729876_1730251_-\|Asp23/Gls24-family-envelope-stress-response-protein	gnl\|CDD\|224221	COG1302, COG1302, Uncharacterized protein conserved in bacteria [Function unknown].	1.7844e-34
NZ_CP040883.1\|WP_001830184.1\|1722137_1722371_-\|acyl-carrier-protein	gnl\|CDD\|179197	PRK00982, acpP, acyl carrier protein; Provisional.	1.2999e-31
NZ_CP040883.1\|WP_001832559.1\|1713421_1713925_-\|ribosome-maturation-factor-RimM	gnl\|CDD\|234650	PRK00122, rimM, 16S rRNA-processing protein RimM; Provisional.	1.61565e-69
NZ_CP040883.1\|WP_002439483.1\|1714051_1714327_-\|30S-ribosomal-protein-S16	gnl\|CDD\|223306	COG0228, RpsP, Ribosomal protein S16 [Translation, ribosomal structure and biogenesis].	4.31598e-41
NZ_CP040883.1\|WP_001830099.1\|1725232_1725793_-\|transcription-factor-FapR	gnl\|CDD\|179847	PRK04424, PRK04424, transcription factor FapR.	1.79193e-99
NZ_CP040883.1\|WP_002469385.1\|1723325_1724252_-\|ACP-S-malonyltransferase	gnl\|CDD\|223408	COG0331, FabD, (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism].	1.85618e-127
NZ_CP040883.1\|WP_001830173.1\|1731519_1732164_-\|ribulose-phosphate-3-epimerase	gnl\|CDD\|238244	cd00429, RPE, Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose phosphate pathway. In the Calvin cycle Ru5P is phosphorylated by phosphoribulose kinase to ribulose-1,5-bisphosphate, which in turn is used by RubisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase) to incorporate CO2 as the central step in carbohydrate synthesis.	3.21388e-115
NZ_CP040883.1\|WP_002456575.1\|1721285_1722023_-\|ribonuclease-III	gnl\|CDD\|234633	PRK00102, rnc, ribonuclease III; Reviewed.	2.98269e-117
NZ_CP040883.1\|WP_002469384.1\|1724253_1725231_-\|phosphate-acyltransferase-PlsX	gnl\|CDD\|235414	PRK05331, PRK05331, phosphate acyltransferase PlsX.	1.20323e-175
NZ_CP040883.1\|WP_002456573.1\|1716366_1717593_-\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	0
NZ_CP040883.1\|WP_001829466.1\|1712684_1713422_-\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	gnl\|CDD\|234581	PRK00026, trmD, tRNA (guanine-N(1)-)-methyltransferase; Reviewed.	7.08021e-168
NZ_CP040883.1\|WP_002484841.1\|1717589_1721159_-\|chromosome-segregation-protein-SMC	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	0
NZ_CP040883.1\|WP_002457379.1\|1716032_1716365_-\|putative-DNA-binding-protein	gnl\|CDD\|234647	PRK00118, PRK00118, putative DNA-binding protein; Validated.	2.69203e-43
NZ_CP040883.1\|WP_002436293.1\|1712228_1712579_-\|50S-ribosomal-protein-L19	gnl\|CDD\|235418	PRK05338, rplS, 50S ribosomal protein L19; Provisional.	4.1359e-69
NZ_CP040883.1\|WP_001830107.1\|1730608_1730797_+\|50S-ribosomal-protein-L28	gnl\|CDD\|234736	PRK00359, rpmB, 50S ribosomal protein L28; Reviewed.	1.3072e-18
NZ_CP040883.1\|WP_002456580.1\|1728203_1729862_-\|DAK2-domain-containing-protein	gnl\|CDD\|274671	TIGR03599, YloV, DAK2 domain fusion protein YloV. This model describes a protein family that contains an N-terminal DAK2 domain (pfam02734), so named because of similarity to the dihydroxyacetone kinase family family. The GTP-binding protein CgtA (a member of the obg family) is a bacterial GTPase associated with ribosome biogenesis, and it has a characteristic extension (TIGR03595) in certain lineages. This protein family described here was found, by the method of partial phylognetic profiling, to have a phylogenetic distribution strongly correlated to that of TIGR03595. This correlation implies some form of functional coupling.	0

>NZ_CP040883.1|WP_001830184.1|1722137_1722371_-|acyl-carrier-protein
MENFDKVKDIIVDRLGVDADKVTEDASFKDDLGADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKYINSLEK
>NZ_CP040883.1|WP_002456575.1|1721285_1722023_-|ribonuclease-III
MANQKKKEMVHDFQQKFTDKMKSLGLHFKNIDLYQQAFSHSSFINDFNMNRLEHNERLEFLGDAVLELTVSRYLFDRHPHLPEGNLTKMRATIVCEPSLVIFANKIKLNELILLGKGEEKTGGRTRPSLISDAFEAFVGALYLDQGLDSVWTFAEKVIFPYVEDDELVGVVDFKTQFQEYVHSQNKGDVTYQLIKEEGPAHHRLFTSEVILENKAVAEGKGKTKKESEQKAAEQAYKLMKNKKSL
>NZ_CP040883.1|WP_002484841.1|1717589_1721159_-|chromosome-segregation-protein-SMC
MVYLKSIDAIGFKSFADHTNVQFDKGVTAIVGPNGSGKSNITDAIKWVLGEQSAKSLRGAKMEDIIFSGAEHRKAQNFAEVKLKLDNHSQKLQIDSEELVVTRRLYRSGESEYYLNNDRARLKDIIDLFLDSGLGKEAFSIISQGRVDEILNAKPINRRQIIEESAGVLKYKKRKAESIQKLDHTEDNLNRVEDILYDLEGRVEPLKEEAAIAKEYKQLSKEMEQSDVIVTVSDIDHYTEDNQRLDERLNHLKSQQAEKEGQQAQINQLLQKYKGKRQQNDYDIEKLNYELVKATENYEQLSGKLNVLEERKKNQSETNARYEEELDNLESQIDSIKNEKAQNEKLLADLKNKQKQLNKEVQELESLLYISDEQHDEKLEEIKNSYYTLMSEQSVVNNDIRFLEHTINENEAKKSRLDSRLVEAFNQLKDIQQNITQTQKEYQSSKKSMEKVEQNIQQLEQQLTDSKRLLSEYENKLYQAYRYNEKLKSRIDSLATQEEDYTYFFNGVKHILKAKDKELRGIHGAVAEVINVPSEMTQAIETALGASLQHVIVDNEKDGRQAIQYLKQRGLGRATFLPLNVIQPRHVAADIKDVARGSQGFINIASDAINVSAKYQNIIENLLGNTIIVENLKHANELARAIRYRTRIVTLEGDVVNPGGSMTGGGARKTKSILSQKDELSTMRNQLEDYQRQTAEFERQFKEQKTQAEQLSEQYFSASQQYNNLKEQVHHHELELDRLKTQEAHLKNEHEEFEFEKNDGYQSDKSKETLKEKQNHLIEIQQQLKQLESDIERYTQLSKEGKASTHQTQQQLHQKQSDLAVVKERIKSQKQVYERLDKQLSDSERQKIEVNEKIKLFNSDEMMGKDAFEKLKEQIQQQENVRQNLNQQLSEIKQQRKDLNEKIEINESQLQKCHQDILFIENHYQDIKAKQSKLDVLINHAIDHLNDTYQLTVERARMEYDSDETIDNLRKKVKLTKMSIDELGPVNLNAIEQFEELNERYTFLNEQRTDLREAKETLEQIIHEMDKEVEGRFKTTFHAVQDHFTTVFKQLFGGGQAELRLTEDDYLSAGVDIIVQPPGKKLQHLSLLSGGERALSAIALLFAILKVRSAPFVILDEVEAALDEANVIRYAQYLNELSTETQFIVITHRKGTMEFSDRLYGVTMQESGVSKLVSVNLNTIDEVMKEEQA
>NZ_CP040883.1|WP_002456573.1|1716366_1717593_-|signal-recognition-particle-docking-protein-FtsY
MSFFKRLKDKFSSKSEDDIQKDLDETVDSNANSDSDSMDPNDSDEQVKPKKKPKKLSEADFDEDGLISIEDFEEIEAQKIGAKFKAGLEKSRQNFQEQLNNLIARYRKVDEDFFEALEEMLITADVGFNTVMKLTDELRTEAQRRNIQETEDLREVIVEKIVEIYHQEDDYSEAMNIEDGRLNVILMVGVNGVGKTTTIGKLAYRYQQEGKKVMLAAGDTFRAGAIQQLNVWGERVGVEVVSQNEGSDPAAVVYDAINAAKNKGVDILICDTAGRLQNKSNLMQELDKMKRVINRAIPDAPHEALLCLDATTGQNALSQARSFKEVTNVSGIVLTKLDGTAKGGIVLAIRNELHIPVKYVGLGEKMDDLQPFNPESYVYGLFADMIEQNEDIPEEISRNSSVESEEGN
>NZ_CP040883.1|WP_002457379.1|1716032_1716365_-|putative-DNA-binding-protein
MGQNDLVKTLRMNYLFDFYQSLLTNKQKNYLELFYLQDYSLSEIADTFEVSRQAVYDNIRRTGDLVEDYESKLRLYQRFEKRRELYNLMKQSLNQPELLKQYITQLEELE
>NZ_CP040883.1|WP_001830113.1|1714634_1716002_-|signal-recognition-particle-protein
MAFEGLSDRLQATMQKMRGKGKVTEADIKTMMREVRLALLEADVNFKVVKEFVKTVSERALGSDVMQSLTPGQQVIKIVQEELTSLMGGENTSIKMANKPPTVVMMVGLQGAGKTTTAGKLALLMRKKYNKKPLLVAGDIYRPAAIDQLQTVGKQIDIPVYSEGDQVSPQQIVENALKHAKEEHLDFVIIDTAGRLHIDEALMNELQEVKEISKPDEIMLVVDAMTGQDAVNVAQSFDEQLDVSGVTLTKLDGDTRGGAALSIRSVTQKPIKFVGMSEKLDGLELFHPERMASRILGMGDVLSLIEKAQQDVDQEKAKDLEKKMRESSFTLDDFLEQLDQVKNLGPLDDIMKMIPGMNKMKGLDKLNMSDKQIDHIKAIIQSMTPKERSNPETLNVSRKKRIAKGSGRSLQEVNRLMKQFNDMKKMMKQFTGGGKGKKAKRNQMQNMLKGMNLPF
>NZ_CP040883.1|WP_002439483.1|1714051_1714327_-|30S-ribosomal-protein-S16
MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQLGTYNPAHVNAPEVKIDEELALKWLHDGAKPTDTVHNILSREGILKKFDEQKNAK
>NZ_CP040883.1|WP_001832559.1|1713421_1713925_-|ribosome-maturation-factor-RimM
MEVEVGQIVNTHGIKGEVKVKSNSDFTETRFQPGEQLLVKHNNTEIVYTVASYRIHKGFHMLRFEGINNINEIEHLKGDYIYQERDHQDIELGEHEYYYSDIIGCTVFKDDDTPIGRVINIFETGANDVWVVKGEKEYLIPYIEDVVKDIDIETKTIKITPMEGLLD
>NZ_CP040883.1|WP_001829466.1|1712684_1713422_-|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD
MKIDYLTLFPEMFEGVLNHSILKRAQDKGIINVNTINFRDYSINKHNQVDDYPFGGGQGMVLKPEPVFNAMEDINHNEHTRVILMCPQGRPFTQEIAQELSEAKHIVFICGHYEGYDERIRKHLVTDEISMGDYVLTGGELPAMTMTDAIVRLIPGVLGNQASHQDDSFSDGLLEFPQYTRPREYKNMSVPEVLLSGNHAHIDQWRHEQKLIRTYEKRPDLLEQYPLTEKDREILETYKKKLKND
>NZ_CP040883.1|WP_002436293.1|1712228_1712579_-|50S-ribosomal-protein-L19
MSNHKLIEAVTKSQLRTDLPTFRSGDTLRVHVRIVEGSRERIQVFEGVVIKRRGGGISETFTVRKISSGVGVERTFPLHTPKIEKIEVKRRGKVRRAKLYYLRSLRGKAARIQEIR
>NZ_CP040883.1|WP_001830161.1|1722598_1723333_-|3-oxoacyl-[acyl-carrier-protein]-reductase
MNKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKDKAEAVVEEIKAKGVESFAIQANVAKGDEVKEMIKEVVSQFGSVDVLVNNAGITKDNLLMRMKEQEWDDVIDTNLKGVFNCIQKVTPQMLRQRSGAIINLTSIVGAMGNPGQANYVATKAGVIGLTKTAARELASRGITVNAVAPGFIVSDMTNALSDDLKDQMLEQIPLKRFGEDTDIANTVAFLASDKAKYITGQTIHVNGGMYM
>NZ_CP040883.1|WP_002469385.1|1723325_1724252_-|ACP-S-malonyltransferase
MGKIAVVFPGQGAQKVGMASDLYNEEERSTRVLNLAQETVDFDLLETMFTDNDGKLGETENTQPALLTHSVALLESLNHLKVDYTMGHSLGEYSSLVSSGVLSFEDAVRIVRKRGQLMAQAFPNGVGGMAAVLGLDYDDVDKICQTLSTKEQLIEPANINSPGQIVVSGHKSLIDELVEKGKELGAKRVLPLAVSGPFHSSMMKVIEEDFANFINQFEWHNANYPVVQNVNAKGETDAEVIKRNMVKQLYSPVQFIQSTEWLINQGVDHFIEIGPGKVLSGLIKKINRDVKITSIQTLEDVKGWNNHE
>NZ_CP040883.1|WP_002469384.1|1724253_1725231_-|phosphate-acyltransferase-PlsX
MVKIAVDMMGGDDAPGIVLDAVKKAVEDFKDLEIILFGDESQYNLSHERIEFRHCTEKIEMEDEPVRAIKRKKDSSMVKMAEAVKSGEADGCVSAGNTGALMSAGLFIVGRIKGVARPALVVTLPTTDGKGFVFLDVGANADAKAEHLLQYAQLGNIYAQKIRGIQNPSVSLLNIGTEAAKGNSLTKKAYDLFEKNQSFNFTGNIEAKTLMDGNVDVVVTDGYTGNMVLKNLEGTAKSIGKMLKETIMSSFKNKLAGAVLKKDLETFAKKMDYSEYGGSVLLGLDGTVVKAHGSSNAKAFYSAIRQAKIAGEENIVQIMKDTVGE
>NZ_CP040883.1|WP_001830099.1|1725232_1725793_-|transcription-factor-FapR
MKLKKNDRRVAIKEAIELNPFITDYELCEKFDVSIQTIRLDRTHLNIPELRKRIKLVAEQNYGRIKSIEANEIIGDLIQVNPDVSAQSLIEITIDSVFAKSEIARGHVLFAQANSLCVALIHKPIVLTHESQVEFKEKVKLNDTVRADARVIDITDKHYIIEVNSYVSDMLVFKGKFKMYYTSEDE
>NZ_CP040883.1|WP_002456579.1|1725951_1728000_-|ATP-dependent-DNA-helicase-RecG
MSKVHLIESPYALDKIKGIGPKRLALLEELNIKSVEDLVLYLPTRYEDNTVIDLNQADDQATVTVQGEVYSSPTVAFFGRNKSKLTVHLMINHIAVKCVFFNQPYLKKKLELNSIVTIKGKWNRNKQEINGNRIFFKDQKNQEDTHLEPIYRIKEGIKQKQLRDNIRQALSDVTIHEWLTDDLREKYKLETLAYTIQTLHHPINKQNLLRARRTYAFTELFMFELRMQWLNRLEKTSDEAIEINYDINKVKQFIDSLPFELTDAQKVSVNEIFRDLKAPIRMHRLLQGDVGSGKTVVAAICMYALKTAGYQSALMVPTEILAEQHAESLIQLFGNTMNVALLTGSVKGKKRRLLLEQLENGTIDCLIGTHALIQDDVVFNNVGLVITDEQHRFGVNQRQILREKGAMTNVLFMTATPIPRTLAISVFGEMDVSSIKQLPKGRKPIKTSWAKHEQYDQVLAQMSNELKKGRQAYVICPLIESSEHLEDVQNVVALYESLQSDYGNEKVGLLHGKMSAEDKDQVMQKFSEHEIDILVSTTVVEVGVNVPNATFMMIYDADRFGLSTLHQLRGRVGRSEHQSYCVLIASPKTETGIERMTIMTQTTDGFELSERDLEMRGPGDFFGVKQSGLPDFLVANVVEDYRMLEVARDEAAELIQSGQFFEQQYSHLREFIKQNLRHIRFD
>NZ_CP040883.1|WP_002456580.1|1728203_1729862_-|DAK2-domain-containing-protein
MISKINGKLFADMIIQGAQNLSNNADLVDSLNVYPVPDGDTGTNMNLTITSGREEVENNLSQNIGELGKTFSKGLLMGARGNSGVILSQLFRGFCKNIEEEKEISVQQFAESFQAGVETAYKAVMKPVEGTILTVAKDAAKAAMDYVDQAEDCVDLMAHLIEAASESLDNTPNLLAVLKEVGVVDSGGKGLLCVYEGFLKGLKGEKIEAQAPKLDTESFVNDDHDFHGVINTEDIVYGYCTEMMVRFGKNKKAFDEQEFRNDMSEFGDSLLVINDDEIVKVHVHTEHPGDVFNYGQKYGELIKLKVENMREQHREVIRKEQDGLQSKEANESKTVETAIVTISVGDGIAELFKSMGATHIISGGQTMNPSTEDIVKVIEQSQCKRAIILPNNKNIMMASEQAASIVEAETVVIPTKSIPQGISALFQYDLESSLEDNKRHMSDALETVQSGSITFAVRDTKIDGIEIKKDEFMGLAEDKIVTSDVNQFHAVKGLLSKLLNEDSEILTMISGEDADNSITNQIINWIESEYPDVEVEQHEGGQPIYQYFFAVE
>NZ_CP040883.1|WP_001830156.1|1729876_1730251_-|Asp23/Gls24-family-envelope-stress-response-protein
MTLEISNDYGKIDISNDVIASVVGGKAVESYGIVGMASRQQVRDGIAEILGHDNYAKGIKVREDNGIIDVDMYIIVSYGVKISEVASNLQSTVKYTLEKTLNVKVNSINIFVQGVRVNETVKKV
>NZ_CP040883.1|WP_001830107.1|1730608_1730797_+|50S-ribosomal-protein-L28
MGKQCFVTGRKASTGNHRSHALNANKRRWNANLQKVRILVDGKPKKVWVSARALKSGKVTRV
>NZ_CP040883.1|WP_001830164.1|1730879_1731515_-|thiamine-diphosphokinase
MKINLLCSQRLLPNHIFEKEKDSNWAGIDRGALILVKQGIQPIFSVGDFDSVNNEERLMLMKNLQIEPVEAEKDDTDLALGVAQAVERGYTEITIYGATGGRLDHFMGVLQILQKPQYLHQSIKIKVIDQQNHIQLLNEGKYVINRDSTYPYISFIPLNDKTILTLQGFKYNLNQEHLNLGSTLTISNEVKVNEAIIRVEQGTVLKIRSRD
>NZ_CP040883.1|WP_001830173.1|1731519_1732164_-|ribulose-phosphate-3-epimerase
MVKILPSLLSIDFLNLKEELQLLETAKVDGLHFDVMDGKFVPNISIGIPILDAVRQQSHLPIDVHLMIEQPENYINLFAEHGADMISVHVESTTHIHRAIEQIKQLGKKAGVVINPGTSVETILPILSIVDYVLVMTVNPGFGGQTFIEQCVTKIEQLNQLKHENHLTFDIEVDGGINDQTSKRCVEQGATMLVTGSYFFKQEDYAKVTSLLKE

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Crispr_ID: NZ_CP040883_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040883_3

2034010-2034105

Orphan

Consensus_repeat	Method
CACTGCAATTTTTAATTGCTTGTGTCACTTATG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040883_3

>merge|NZ_CP040883|3|2034010-2034105|CRISPRCasFinder
CACTGCAATTTTTAATTGCTTGTGTCACTTATGCTTGAGCTTTGCTCAGGCGTTCCTCTTTTTCACTGCAATTTTTAATTGCTAGTGTCACTTATG

>NZ_CP040883|3|3|2034010-2034105|CRISPRCasFinder
CACTGCAATTTTTAATTGCTTGTGTCACTTATG	CTTGAGCTTTGCTCAGGCGTTCCTCTTTTT
CACTGCAATTTTTAATTGCTAGTGTCACTTATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040883.1\|WP_002438990.1\|2030456_2031269_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_CP040883.1\|WP_001831907.1\|2035240_2035564_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP040883.1\|WP_001829623.1\|2038593_2039094_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
NZ_CP040883.1\|WP_002484545.1\|2031977_2033003_-\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NZ_CP040883.1\|WP_002457221.1\|2037246_2037669_+\|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
NZ_CP040883.1\|WP_002438979.1\|2034190_2034571_-\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_CP040883.1\|WP_001831939.1\|2028736_2029597_+\|DUF368-domain-containing-protein	unknown	unknown	gnl\|CDD\|224946
NZ_CP040883.1\|WP_001831967.1\|2029662_2029854_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_CP040883.1\|WP_162161215.1\|2037852_2037990_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040883.1\|WP_001831898.1\|2026251_2027559_-\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NZ_CP040883.1\|WP_001831968.1\|2033544_2033931_-\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
NZ_CP040883.1\|WP_001829615.1\|2039364_2039952_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|366010
NZ_CP040883.1\|WP_001831936.1\|2033255_2033552_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP040883.1\|WP_001831893.1\|2030028_2030187_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040883.1\|WP_001831944.1\|2027653_2028415_-\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NZ_CP040883.1\|WP_001831974.1\|2036369_2037086_-\|type-I-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
NZ_CP040883.1\|WP_001831981.1\|2035746_2036289_-\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
NZ_CP040883.1\|WP_001831965.1\|2034744_2035098_-\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
NZ_CP040883.1\|WP_001831910.1\|2031289_2031985_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NZ_CP040883.1\|WP_002457224.1\|2040165_2040402_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP040883.1\|WP_002438990.1\|2030456_2031269_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	1.91141e-110
NZ_CP040883.1\|WP_001831907.1\|2035240_2035564_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	1.68543e-25
NZ_CP040883.1\|WP_001829623.1\|2038593_2039094_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	1.80445e-49
NZ_CP040883.1\|WP_002484545.1\|2031977_2033003_-\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	1.2337e-166
NZ_CP040883.1\|WP_002438979.1\|2034190_2034571_-\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	1.44293e-69
NZ_CP040883.1\|WP_001831939.1\|2028736_2029597_+\|DUF368-domain-containing-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	5.03423e-64
NZ_CP040883.1\|WP_001831967.1\|2029662_2029854_-\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	0.000312009
NZ_CP040883.1\|WP_001831898.1\|2026251_2027559_-\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	4.59041e-133
NZ_CP040883.1\|WP_001831981.1\|2035746_2036289_-\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	7.82596e-53
NZ_CP040883.1\|WP_001829615.1\|2039364_2039952_-\|histidine-phosphatase-family-protein	gnl\|CDD\|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	1.38205e-50
NZ_CP040883.1\|WP_001831936.1\|2033255_2033552_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	1.51609e-11
NZ_CP040883.1\|WP_001831968.1\|2033544_2033931_-\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	1.04994e-30
NZ_CP040883.1\|WP_001831944.1\|2027653_2028415_-\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.04582e-150
NZ_CP040883.1\|WP_001831974.1\|2036369_2037086_-\|type-I-3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	1.58421e-151
NZ_CP040883.1\|WP_002457221.1\|2037246_2037669_+\|organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	2.58332e-60
NZ_CP040883.1\|WP_001831965.1\|2034744_2035098_-\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.66742e-56
NZ_CP040883.1\|WP_001831910.1\|2031289_2031985_-\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	8.39327e-99

>NZ_CP040883.1|WP_001831968.1|2033544_2033931_-|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPANIICTHGTMSIDKIDNMIETLYDKQVYVLADSDDEGEKIRKWFKRYLSESEHIYVDKTFCEVAKCPKNYLAHVLSRYGFNVKKEKKLMNNLKTERLVLVNE
>NZ_CP040883.1|WP_001831936.1|2033255_2033552_-|thioredoxin-family-protein
MNKLKDIEDITVNFNKEKHLIFGYTPMCGTCKISERMLDIANEILQLPIKKIDLNFYPEWSKEKQIMSVPVLLLMRREEEIKRIYAFQSVTYLLENLK
>NZ_CP040883.1|WP_002484545.1|2031977_2033003_-|methionine-ABC-transporter-ATP-binding-protein
MIKLNQIVKRYHTKDKDVLAVDHVDLNIESGSIFGVIGFSGAGKSTLIRMFNNLESPTSGEIIIDGNNISQLSKSQLRKKRQKVSMIFQHFNLLWSRSVLKNVTFPLEIAGVPSGLAKQKALELIELVGLKGRESAYPSELSGGQKQRVGIARALANDPDVLLCDEATSALDPQTTDEILDLLLKVREQQNLTIVLITHEMHVIRRICDEVAVMENGKVIEQGAVSKVFENPQHEVTKRFVKDDLNDDFEDSLEYLEPLDHDAYIVRLNFTGENTTEPIISYMTKTHNIDVNILEADIKNTKNGSLGFLVIHIPHISEEHFKQFKHNLHEQHVNVEVLKHG
>NZ_CP040883.1|WP_001831910.1|2031289_2031985_-|ABC-transporter-permease
MGKSYGEIFHEMVTMPNVQWPEVWQAILETLYMTVVSTLFAFVFGLILGVLLFLSAKSNSLAAKIFYTIVSFIVNLFRAIPFIILILLLIPFTSILLGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTSIVVRKVLLPEAMPALVSGITVTAIALVGSTAIAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFLGDWLTNKIDKR
>NZ_CP040883.1|WP_002438990.1|2030456_2031269_-|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGIILVLALTIALAACGGGKDKEKTITVGASPAPHAEILEKAKPLLKKKGYDLKIKPINDYTTPNKLLDKGEIDANFFQHTPYLNTESKEKGYKIESAGNVELEPMAVYSKKYKSLKDLPKGATVYVSNNPAEQGRFLKFFVDEGLIKLKKGVKIENAKFDDITENKKDIKFNNKQSAEYLPKIYQNQDADAVIINSNYAIDQKLSPKKDSIALESPKDNPYANLIAVKKGHKDDKNIKVLMEVLQSKEIQDYIKDKYDGAVVPAK
>NZ_CP040883.1|WP_001831893.1|2030028_2030187_+|hypothetical-protein
MKFITIKAITEKGLDKKVNQFLKSHPQIEIIKFDYQMGYSGVSVGILYRDNI
>NZ_CP040883.1|WP_001831967.1|2029662_2029854_-|CsbD-family-protein
MAEDKFEQAKGNIKETVGNATDNKELEKDGKGDKASGKAKEAVENVKEKANDVIDKFKGNKGD
>NZ_CP040883.1|WP_001831939.1|2028736_2029597_+|DUF368-domain-containing-protein
MKKFKWINIFKGFGMGTSDLVPGVSGGTIALLLGIYDDFISSISGLFSRRFWPSLKFLLPILVGMLIAIGLLSQLFNYLLSQHHIPTMLFFTGLILGIIPYLLTISNFKKNFSIIHYFILLLGIAIIVVFALLNHGDKHSGETLTLSFSLIIKYFIAGVFASSAMLLPGISGSFMLLVFGVYGTLMYAISELLHFNLNALPIILIVGFGIVTGFMISSRLIQYCLHQHPTMTFALIIGFVIGSLYAVFPGFPKDLIQWIISFFLLITGFLVSYVLGKITAKNEASF
>NZ_CP040883.1|WP_001831944.1|2027653_2028415_-|Fe-S-cluster-assembly-ATPase-SufC
MSSTLEIKDLHVSIEDKEILKGVNLTINTGEIHAIMGPNGTGKSTLSSAIMGHPSYEVTQGEVLLDGVNILELDVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKQMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGEEFGALMITHYQRLLNYITPDKVHVMYGGKVVKSGGPELAKRLEEEGYEWVKEEFGAAE
>NZ_CP040883.1|WP_001831898.1|2026251_2027559_-|Fe-S-cluster-assembly-protein-SufD
MTTKTLNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDTFKQHHTTGDAYTQLTDLPKSVKEIIDVENSENLIIQHNNELAYTQVSDQAKHDGVIIEGLSEALVNHSDLVQKYFMTKAVDVDEHRLTALHTALVNGGIFVYVPKNTVVEHPIQYVVLHDDEQASFYNHVIIVTEESAEVTYVENYLSTTSGEDNQLNIVSEVIAGANSNVTYGSVDYLDKGFTGHIIRRGSADADASINWALGLMNEGSQIIDNTTNLNGDRSTSALKSVVVGTGDQKINLTSKIVQYGKETDGYILKHGVMKENASSVFNGIGYIKHGGTKSIANQESRVLMLSENARGDANPILLIDEDDVEAGHAASVGRVDPEQLYYLMSRGISRAEAERLVIHGFLDPVVRELPIDDVKRQLREVIERKVSK
>NZ_CP040883.1|WP_002438979.1|2034190_2034571_-|glycine-cleavage-system-protein-GcvH
MAVPSEFKYSKEHEWVKIENNVATIGITEYAQNELGDIVFVELPETDDELNEGDTFGSVESVKTVSELYAPISGKIVEVNEELEDSPEFVNESPYEKAWMVKIEISDDSQLEELLSADQYSEMIGE
>NZ_CP040883.1|WP_001831965.1|2034744_2035098_-|arsenate-reductase-family-protein
MIKFYQYPKCTTCKKAAKFLDEHDVNYESIDIVQHTPTKKEFKNIVDKTGVNINKLFNTHGIKYRELNLKEKLKNMSDDEKLELLASDGMLVKRPLAISGNHLTLGFKENEYQHQWL
>NZ_CP040883.1|WP_001831907.1|2035240_2035564_+|thioredoxin-family-protein
MKNIHQTEEFNSTIGSTDPVIIKFEADWCPDCKAMDMWIDPIVEKYNNYQWYVVDRDELEDVTTENDVMGIPSILIFQNGKKLAHLHSANAKSPEQVESFLTEHLDQ
>NZ_CP040883.1|WP_001831981.1|2035746_2036289_-|nitroreductase
MELQEAISNRRSVKKFKHDMVVDDQTVYDAIYKATDAPNHGMREPWRLVHISKDKLGDFSRDITRFAFPDSPDKREDHFHAVTNLGGMLLLILKDDPRQRQSRENYFAFGAFAQNLMLLLYEAGIGTCWKSPQYIFDPKIRKALGVKDNEILAGFLYLTDLEEVPTKAKRKNKNLITEFE
>NZ_CP040883.1|WP_001831974.1|2036369_2037086_-|type-I-3-dehydroquinate-dehydratase
MTHVDIAATIAPEDKLSKTLLKDIKVNEESIDIIELRIDQWPSFNKALLNEVIKQLKIFHLKILVTYRTSVQGGKGAVNEQEYLNILGELIECPQFDMIDIEWSSAVKIEKYTHLVQRAQQKGLEVVLSHHNFQETPALDELKFIYFKMQKLNPEYLKLAVMPKCQEDVLHLLEAMSLTAKHTTCRIVGISMSSLGKVSRIAQGVFGGTLSYGCIEEPQAPGQIHVSKLKSMVSFYED
>NZ_CP040883.1|WP_002457221.1|2037246_2037669_+|organic-hydroperoxide-resistance-protein
MAVQYETKATNVGGRKGHVHTDDNAINVDVLPPQQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAEPEVTLTVRLEDDPDAESPKLSVDIHAKVKNVLSQEDAEKYLQDAHDFCPYSKATRGNIDVNLNVEVVE
>NZ_CP040883.1|WP_162161215.1|2037852_2037990_-|hypothetical-protein
MTQHTLPMETSVLIPTNDISRHVNDIVETIPDTEFDEFRHHCGLI
>NZ_CP040883.1|WP_001829623.1|2038593_2039094_+|GNAT-family-N-acetyltransferase
MNNIRLLNQNDLDSYIELMKFGHHNYEWDRYYLENVSIDRLKTILSNHTDYWNIFGAFEDDELVATCTLKQMNYVGKCHKAILENNFVKNNDEIVNRELINHIIQYAKEQNIETLMIAIASNNISAKVFFSSIGFENLAFEKNASKIGNEYFDENWLIYSTTESSD
>NZ_CP040883.1|WP_001829615.1|2039364_2039952_-|histidine-phosphatase-family-protein
MVKTLYLMRHGQTVFNLKGKIQGASDSPLTALGVQQANAAQQYFKTKNIHFDYLYSSPQQRACDTLENAVPNQQYWCVKDLKEWGFGLFEGESIELLRAIKQPRYLYGDAVVPFGGESRSEVEHRVYRALYEMMDTTDGETILAVSHGSTIGLFVRNILGYDKGSKFEIGNCNIVKFEYDGEEFIFKDLINPIKK
>NZ_CP040883.1|WP_002457224.1|2040165_2040402_+|hypothetical-protein
MSTHSQCNYVNPNSISLDWECLIISKTDMLLDGVPKELINTWLDQNVIEPFCVRNNEINFKTKDVWNALKTHNWYYSN

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Crispr_ID: NZ_CP040883_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040883_4

2185718-2185808

Orphan

Consensus_repeat	Method
TGTTGAATTTCCCGGTGAAATTCTCTATGTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040883_4

>merge|NZ_CP040883|4|2185718-2185808|CRISPRCasFinder
TGTTGAATTTCCCGGTGAAATTCTCTATGTTGGGGCCCCGAACCCCAACTTGCTTTGCCTGTTGAATTTCTCGGTGAAATTCTCTATGTTG

>NZ_CP040883|4|4|2185718-2185808|CRISPRCasFinder
TGTTGAATTTCCCGGTGAAATTCTCTATGTTG	GGGCCCCGAACCCCAACTTGCTTTGCC
TGTTGAATTTCTCGGTGAAATTCTCTATGTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040883.1\|WP_001832056.1\|2179092_2179782_+\|DUF1129-family-protein	unknown	unknown	gnl\|CDD\|368981
NZ_CP040883.1\|WP_001832143.1\|2183620_2184766_-\|nitric-oxide-dioxygenase	unknown	unknown	gnl\|CDD\|237337
NZ_CP040883.1\|WP_001832064.1\|2183415_2183601_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040883.1\|WP_001832142.1\|2178231_2178654_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|130141
NZ_CP040883.1\|WP_002484678.1\|2187841_2190016_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
NZ_CP040883.1\|WP_001832093.1\|2180332_2181541_-\|sugar-efflux-transporter	unknown	unknown	gnl\|CDD\|341024
NZ_CP040883.1\|WP_002455993.1\|2187367_2187727_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|130944
NZ_CP040883.1\|WP_001832022.1\|2194507_2196397_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376899
NZ_CP040883.1\|WP_001832101.1\|2184937_2185612_+\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	unknown	unknown	gnl\|CDD\|183940
NZ_CP040883.1\|WP_001832140.1\|2182533_2183127_-\|DUF402-domain-containing-protein	unknown	unknown	gnl\|CDD\|225188
NZ_CP040883.1\|WP_001832058.1\|2185922_2186399_-\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380376
NZ_CP040883.1\|WP_002457534.1\|2193368_2193986_-\|DUF47-domain-containing-protein	unknown	unknown	gnl\|CDD\|224310
NZ_CP040883.1\|WP_001832176.1\|2190280_2190940_-\|Bax-inhibitor-1-family-protein	unknown	unknown	gnl\|CDD\|223742
NZ_CP040883.1\|WP_001832028.1\|2179837_2180326_-\|DUF456-domain-containing-protein	unknown	unknown	gnl\|CDD\|225395
NZ_CP040883.1\|WP_001832120.1\|2186398_2187115_-\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|237084
NZ_CP040883.1\|WP_001832178.1\|2177803_2178100_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040883.1\|WP_001833013.1\|2196386_2197148_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_CP040883.1\|WP_001832086.1\|2191350_2192151_+\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP040883.1\|WP_001832044.1\|2181598_2182453_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP040883.1\|WP_001832181.1\|2192343_2193354_-\|inorganic-phosphate-transporter	unknown	unknown	gnl\|CDD\|376541

Protein	Function_ID	Function_description	E-value
NZ_CP040883.1\|WP_001832056.1\|2179092_2179782_+\|DUF1129-family-protein	gnl\|CDD\|368981	pfam06570, DUF1129, Protein of unknown function (DUF1129). This family consists of several hypothetical bacterial proteins of unknown function.	0.00246668
NZ_CP040883.1\|WP_001832143.1\|2183620_2184766_-\|nitric-oxide-dioxygenase	gnl\|CDD\|237337	PRK13289, PRK13289, NO-inducible flavohemoprotein.	2.15135e-120
NZ_CP040883.1\|WP_001832142.1\|2178231_2178654_-\|hypothetical-protein	gnl\|CDD\|130141	TIGR01069, Endonuclease_MutS2, MutS2 family protein. Function of MutS2 is unknown. It should not be considered a DNA mismatch repair protein. It is likely a DNA mismatch binding protein of unknown cellular function. [DNA metabolism, Other].	0.00156082
NZ_CP040883.1\|WP_002484678.1\|2187841_2190016_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	5.21095e-20
NZ_CP040883.1\|WP_001832093.1\|2180332_2181541_-\|sugar-efflux-transporter	gnl\|CDD\|341024	cd17471, MFS_Set, Sugar efflux transporter (Set) family of the Major Facilitator Superfamily of transporters. This family is composed of sugar transporters such as Escherichia coli Sugar efflux transporter SetA, SetB, SetC and other sugar transporters. SetA, SetB, and SetC are involved in the efflux of sugars such as lactose, glucose, IPTG, and substituted glucosides or galactosides. They may be involved in the detoxification of non-metabolizable sugar analogs. The Set family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.79377e-100
NZ_CP040883.1\|WP_002455993.1\|2187367_2187727_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.52342e-15
NZ_CP040883.1\|WP_001832022.1\|2194507_2196397_-\|ABC-transporter-permease	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	3.76486e-06
NZ_CP040883.1\|WP_001832101.1\|2184937_2185612_+\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	gnl\|CDD\|183940	PRK13276, PRK13276, iron-sulfur cluster repair di-iron protein ScdA.	3.23993e-150
NZ_CP040883.1\|WP_001832140.1\|2182533_2183127_-\|DUF402-domain-containing-protein	gnl\|CDD\|225188	COG2306, COG2306, Predicted RNA-binding protein, associated with RNAses E/G family [General function prediction only].	6.47504e-72
NZ_CP040883.1\|WP_001832058.1\|2185922_2186399_-\|cupin-domain-containing-protein	gnl\|CDD\|380376	cd06121, cupin_YML079wp, Saccharomyces cerevisiae YML079wp and related proteins, cupin domain. This family includes eukaryotic, bacterial, and archaeal proteins homologous to YML079wp, a Saccharomyces cerevisiae cupin-like protein of unknown function that structurally resembles plant seed storage and ligand-binding proteins (canavalin, glycinin, auxin binding protein) as well as the bacterial RmlC epimerase. YML079wp is non-essential in yeast and localizes to the nucleus and cytoplasm. The presence of a hydrophobic ligand within a well-conserved binding pocket inside the cupin beta-barrel and sequence similarity with bacterial epimerases suggests a possible biochemical function for YML079wp and its homologs. Also included in this family are Shewanella oneidensis So0799, Agrobacterium fabrum Atu3615 and Branchiostoma belcheri Bbduf985. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold and forms a homodimer.	5.85126e-71
NZ_CP040883.1\|WP_002457534.1\|2193368_2193986_-\|DUF47-domain-containing-protein	gnl\|CDD\|224310	COG1392, COG1392, Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism].	4.24041e-54
NZ_CP040883.1\|WP_001832176.1\|2190280_2190940_-\|Bax-inhibitor-1-family-protein	gnl\|CDD\|223742	COG0670, COG0670, Integral membrane protein, interacts with FtsH [General function prediction only].	3.08106e-29
NZ_CP040883.1\|WP_001832028.1\|2179837_2180326_-\|DUF456-domain-containing-protein	gnl\|CDD\|225395	COG2839, COG2839, Uncharacterized protein conserved in bacteria [Function unknown].	2.3208e-34
NZ_CP040883.1\|WP_001832120.1\|2186398_2187115_-\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|237084	PRK12378, PRK12378, YebC/PmpR family DNA-binding transcriptional regulator.	2.97069e-139
NZ_CP040883.1\|WP_001833013.1\|2196386_2197148_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	1.35373e-102
NZ_CP040883.1\|WP_001832086.1\|2191350_2192151_+\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	2.45079e-38
NZ_CP040883.1\|WP_001832044.1\|2181598_2182453_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	4.11693e-40
NZ_CP040883.1\|WP_001832181.1\|2192343_2193354_-\|inorganic-phosphate-transporter	gnl\|CDD\|376541	pfam01384, PHO4, Phosphate transporter family. This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.	3.05703e-103

>NZ_CP040883.1|WP_001832101.1|2184937_2185612_+|iron-sulfur-cluster-repair-di-iron-protein-ScdA
MITKEDIVADVVTDYPKSADIFRNAGIDFCCGGQESIASAVNHKPNIDLNSLLNKLNHIDNTEGNSTINPKFLNVESLIQYIQSAYHETLKEEFKNLTPYMTKLAKVHGPSHPYLLKLQDLYREFRDSMLDHIRKEDEEDFPKLIQYSQGQDVQNIKIILEDLINDHEDTGQLLNVMNQLTSDYQTPEEACGTWKLVYQRLQNIERQTHQHVHLENHVLFKKVS
>NZ_CP040883.1|WP_001832143.1|2183620_2184766_-|nitric-oxide-dioxygenase
MLTEKEQDIIKQTVPLLQDKGTEITSIFYPKMFEANPELLNMFNQTNQKKGMQSAALAQAVLAAAMNINNLGAIKPAIMPVAHKHCALQVYPEHYPIVGENLLAAIQDVTGLESDDPVIQTWAKAYGEIADVFIKLEQEIYNHMLWKGFKPFKITNITQETSDIKSFTVESEEYDLSQFEPGQYITVDVSSEKLPYRAKRHYSIIDGDENHLVFGVKRDVTTEHEGEVSTILHDEISEGDMINLSAPVGGFSIENTERPQLFIGSGVGMTPLVSMFKKAASLNVPTQMIQAVVTEDERPFAQKLDSITDNYEQAQLHLHVKDKEGYLEAKELEQYLSEQPEIYICGGTKFLHSIINSLKELNYDMNHVHFETFIPRLSVQV
>NZ_CP040883.1|WP_001832064.1|2183415_2183601_-|hypothetical-protein
MKMNPRYVKVFFLYLVSTFISNRLTTNKSLCKTLMQGILGYGLFALGLKYLTIKKKQHQAQ
>NZ_CP040883.1|WP_001832140.1|2182533_2183127_-|DUF402-domain-containing-protein
MKVKYIDKRHWRRLVEREYTEVKVNNNRFKGIIGLVTMKKVREPLEVTVVGQNIIVADDNYKWLQILPDKKRYSMTVMFDNKGNPLEYYFDINIKNITQKGNARTIDLCLDVLVLPNGEYELVDEDDLMYALQNKQISKKQYHEAYIIAHQLMIEIEDNFSEIQDKVMRCYHKINHKAQKMKHKRPYKAKKKSHRRH
>NZ_CP040883.1|WP_001832044.1|2181598_2182453_-|LysR-family-transcriptional-regulator
MKIDDYRLLITLDETKTLRKAAEILYISQPAVTQRLKAIEAAFGVEIFIRTKKQLITTTEGSMIIEHARDMLKRERLFFDKIQAHIGEVNGTISIGCSSLIGQTLLPEVLSLYNSQFPNVEIQVQVGSTEQIKAHHRDYHVMITRGNKVMNLSNTHLFNDEHYFIYPKDRKEDVTKLPFIEFQADPIYINQIKQWYNDHLGHDYHATITVDQVATCKEMLLSGVGVTILPKIMMKNIDKNMFEFEKVTIDKKPLIRSTYMSYDASMLQLPQVDAFVNLMLNFIR
>NZ_CP040883.1|WP_001832093.1|2180332_2181541_-|sugar-efflux-transporter
MFTALLQIKNYKLFVVNMLLLGMGIAVTVPYLILFATKDLGMTTTQYGLLLALAAISQFIVNSIIARFSDTHHLNRKILIITALFMGAVSFSIYFYVHQIWLFIVLYALFQGLFAPAMPQLYASARESINASSSRDRAKFANTVLRSMFSLGFLFGPFIGAQLIELKGYSGLFGGTIAIILFTLILQVFFYKNLPVKNQISEQQHIEKIAPNMFKDKSLFIPFIAFILLHIGQWMYTMNMPLFVTDYLNEKERYVGYLASLCAGLEVPFMVILGILSAKLPTRTLLIIGSVFGGAFYFSIGVFKNFHMMLVGQICLAIFLAILLGLGISYFQDILPDFPGYASTLFANAMVIGQLGGNLLGGVMSHWVGLENVFFVSASSIFVGMILILFTKDQKITIEDVE
>NZ_CP040883.1|WP_001832028.1|2179837_2180326_-|DUF456-domain-containing-protein
MTAILWILIIIAFALAFIGLIKPVIPSLLMLWIGFLIYQFGFHEGRLSWIFYVAMIIFTIMILVADFVMNKYFVNRFGGSKIGEYTALIGVIVGCFVFPPFGIIIIPFVAVFIVELVQGFNFQQAIKVSFGSVIAFLASTIAQGLIMIVMVIWFFLDVFLIN
>NZ_CP040883.1|WP_001832056.1|2179092_2179782_+|DUF1129-family-protein
MKSTAQLTKENNVKALRLNNTDREIFENYMTYVRADLRVNPHDSELMLNRTLKHLIRAGDTGMLAMEFFNHDPKAHAKKEIRELPNETFKNIFKYISHNFILLIGIFCFLKGLIGFFIGGDSNLLYLYTFPLTVIIGLVIIFLFIWMNFKTVQLQCFNNSYWTWWLTYGVIALLLITLFYVFFIPQSFLAFGPYIKVSNWTFIIIAIIIIPISFYVNHHFYNKEANTRI
>NZ_CP040883.1|WP_001832142.1|2178231_2178654_-|hypothetical-protein
MRKWLTLLLITTLVLTACGKSNEKASLEKSIDQLKKENKDLKKQKKKLQEQKDKLKHKQDSLQEDVNDLPAKSTSRDKKNKDNHDAKEKSSDNQSTSANHDDQTNKIKSNQDEHDSQSSKPHTQQKPSQNDRKNNHRQER
>NZ_CP040883.1|WP_001832178.1|2177803_2178100_-|hypothetical-protein
MHEQDFNILEGKKMTLVELGRELENLTGRTIKDTTSDIKRVIAHLPNFESDTDTFVATYHLNHQNDFIDATFVAPKNQSDRLKEIPVHIKLISYISKN
>NZ_CP040883.1|WP_001832058.1|2185922_2186399_-|cupin-domain-containing-protein
MMTANDWIDRLELISHPEGGYFKETMRGDGKGRASFSSIYFLLTQRDISHFHRIDADEVWYYHAGQTLKIHMITPKGEYHTVKLGRDIDCGECLQYCVPKGTIFASTLDSAEGYSLVGCMCQPGFEYEHFELLTQEYLIRQYPQYESIIKRLAISQED
>NZ_CP040883.1|WP_001832120.1|2186398_2187115_-|YebC/PmpR-family-DNA-binding-transcriptional-regulator
MGRKWNNIKEKKAQKDKNTSRIYAKFGKEIYVAAKSGEPNPESNQTLRLVLERAKTYSVPNHIIDRAIDKAKGAGDENYDHLRYEGFGPNGSMLIVDALTNNVNRTASDVRAAFGKNGGNMGVSGSVAYMFDHTATFGVEGKSVDEVLETLMEQDIDVRDVIDDNGLTIVYAEPDQFAQVQDALREAGVEEFKVAEFEMLPQTDIELSEEDQAIFEKLIDALEDLEDVQNVFHNVDLK
>NZ_CP040883.1|WP_002455993.1|2187367_2187727_-|MarR-family-transcriptional-regulator
MNEQKLIKLLEFYKQYKALSGYIDKKYKLTLNDLAVLYLAKKYCLDERILMQTFLKLATGELDISRTKILMSIRRLIDKEKLNKVRSNRDERKIFLYMDENNMSEFDALFEDVEKFLSY
>NZ_CP040883.1|WP_002484678.1|2187841_2190016_-|AraC-family-transcriptional-regulator
MANSCLHILSKKEYTATRCQDGILLFWPIEGSMHFQQFMKERILSDELYIVNNMDVFSISDNGITLEVYISSDWFTELGYSFFNYHYISDLIQSKNEIKELVAQLTLNFLDNDVDKEQDIINKIVHILANEAIIDKKIAEDQYMYDYYGELKDELNYIYNHIEERLTLKDISNKLYVSKSNLSTQFHLLLGMGFKKYIDTLKISKSIEMLLTTTKTISQISETLGFSNVSTYSRQFKNYLSVTPNAYRAMKKYDKYNGCSDDDVSEHLKSRVQSLICSKMPTNELDNYDEIVIDQYPISNVSTFYSVVQINSIDEIKMLFLQGIHKKIGYEGSNIIFCIMPNLCQYKNSFSQEEMNDIIKIIIEYRLHVAFSIDKIEQIYELNQLFTYQYENLKIMNKCSVSDYNVQFIFNLNEKSIREIYRNILKIQNIELEYKIGLDISCMFNDTAQFKSLASQIKRLKFDYLYIDNARLKSPYLLDNEEGLLLKNILQFKHLIDDLKQFDFSSENLIFLNLYNHQLLNNNEIDLSNSAPLLFKTISKLKKHFKGYGLNVFSNPKVFNAVHLFDENGFKTTFGLIFNHLSWMTNQNQIEQRFYNIIENADQYYLYLYDWRVIESESNESDFKDVDIWINFEDEALIDEYICVIAKVDDEGGNINHMISQNLRHKYVWSTPFLMRVEENFRPYMHIMEHDFKKGPLKIRMKYNAVYLVEIYKKDKINKRRSTT
>NZ_CP040883.1|WP_001832176.1|2190280_2190940_-|Bax-inhibitor-1-family-protein
MSQSTHQSTDHKRQSQDKNQTHAYAKVWLYFMYYWMIFGIGCYFGQYLPMSWRKPLSLGLLILILATLFIKRARKYGLVISHIYAIIVGLLSYALFTTYLQNLGAEVFYKNIILAIGAFIAFGIIGYFLIKDASSMGKYLFVTLIALIIAGIIGIFINNPIFHTVITIVSLLLFLLYTLYDFNRMKRGQFSPREMGFNLFINLLNIIEDILSLANRFKN
>NZ_CP040883.1|WP_001832086.1|2191350_2192151_+|LysM-peptidoglycan-binding-domain-containing-protein
MKKLAFAITAASGAAAVLSHHDAEASTQHKVQSGESLWTIAQQYNTSVESIKQNNNLSNNMVFPGQVINVGGSASQNTSSNTSSSSASSHTVVAGESLNIIANKYGVSVDALMQANHLNGYLIMPNQILTIPNGGSGSGSGGTATQTSGNYTSPSFNHQNLYTEGQCTWYVFDKRSQAGKPISTYWSDAKYWASNAANDGYQVDNTPSVGAIMQSTPGPYGHVAYVERINGDGSILISEMNYANGPYNMNYRTIPASEVSSYAFIH
>NZ_CP040883.1|WP_001832181.1|2192343_2193354_-|inorganic-phosphate-transporter
MSYILIVTIAIVIFSLIFDFINGFHDTANAVATAVSTRALTPRRAILLAAVMNFIGALTFTGVAGTITKDIVDPFKLQHGLVVVLAAIIAAIIWNLITWLYGIPSSSSHALIGSIAGAAIASQGSFAVLHYQGFTKIIIVLIISPIIAFCVGYMMYTIVKIVFKNSNLTRTNRNFRFFQIFTAALQSFSHGTNDAQKSMGIITLALIVGNLQDGSNVEPQVWVKVACATAMGLGTAVGGWKIIKTVGGNIMKIRPANGAAADISSALTIFVASSLHFPLSTTHVVSSSILGVGASNRAKGVKWSTAQRMVVTWVITLPISAVLAAIIYFIIHLFLK
>NZ_CP040883.1|WP_002457534.1|2193368_2193986_-|DUF47-domain-containing-protein
MFSKKKDKFMVQLEEMVFNLDRAAIEFGKMDFNTHLDLKAYSDNIKTYESHGDELMHQVISDLNQTFITPIEREDILSLCNAIDDVLDAMEETSAMFEMYSIEYTDEYMAEFVENIQKAVAEMKLAVGLLVDKKLSHMRIHSINIKEFETNCDGILRQSMKHIFNSETDPITLIKIKDIYQSMEEIADKCQAVANNFETIIMKNS
>NZ_CP040883.1|WP_001832022.1|2194507_2196397_-|ABC-transporter-permease
MSFNEIIFKNFKQNVTHYAIYLLSLVISVVLYFSFVTLKYAHHLHGNQSFPAIKEGSQVGSYFLFIIIVVFLLYANFLFLKRRGRELSLLQIIGLTKKDIMKMIMLEQLMTFMMTTIVGIILGIFGSKILLMIVLRLLGINVSVSIIFNYHAILETLLLIAVSYVLIVFQSYVYLLKRSIKELASDVNKKEFSHTRTTLGEVVLGLLGIIMIVSGYIMSTKLVDNVETIIQPFAILFLTVIGSYFFFRSTVSLIFKAIQRLRNGTVSVTDVMFTSPIIYRVKKNAFSLTVMTVVSAITVSVLCFAALSRSTLTNEVLLSSPHDVTLKNQKQANELAFKLNNRNIEHYYNYKEVVYAKVYKDHLFSEGVYRPKEITVTSDKYIPNVSTKKGQTDIIIPRGSLKDVVKTDKKRTAYVGSKKFRLKVSLRKGINKVYFMSDVDRGRPTLILNDEDYQKIREHIKEKNIVSQYGFDLKNKNDLPELEKLVSSINEDIETRSEAASEISSLTGILLFVTSFLGITFLIAAGCIIYIKQIDETEDELENYTILRKLGFTHQDMSKGLKLKVIFNFGLPLIIALLHAYFASLAYMHLMNVTNQIPIFIVMAVYTATYAVFAIIAYNHSKRTIKHSI
>NZ_CP040883.1|WP_001833013.1|2196386_2197148_-|ABC-transporter-ATP-binding-protein
MSILEVRQLSKVYGDKQAFQEVLKEINLDVDEGEFISIMGPSGSGKTTLLNVLSSIDYMTKGSITINGKQLEKLSNKQLSDIRKKDIGFIFQDYNILNTLTVKENIMLPLSVQKLDKQIMHERYQRIVEALNISDISDKYPSELSGGQRQRTSAARAFINLPSIIFADEPTGALDSKSTLDLLKRLKYMNEEFNTTILMVTHDPVAASFSNRVVMLKDGQIFTELYQGDDDKQTFYKEIIRTQSVLGGINYEL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP040883_1	1.1\|446455\|34\|NZ_CP040883\|CRISPRCasFinder	446455-446488	34	NZ_CP040883.1	1224905-1224938	2	0.941
NZ_CP040883_1	1.1\|446455\|34\|NZ_CP040883\|CRISPRCasFinder	446455-446488	34	NZ_CP040883.1	1224964-1224997	2	0.941

1. spacer 1.1|446455|34|NZ_CP040883|CRISPRCasFinder matches to position: 1224905-1224938, mismatch: 2, identity: 0.941

gggttcggggccccaacaaagagaatttcaccga	CRISPR spacer
gggttcggggccccaacaaaaagaatttcactga	Protospacer
********************.**********.**

2. spacer 1.1|446455|34|NZ_CP040883|CRISPRCasFinder matches to position: 1224964-1224997, mismatch: 2, identity: 0.941

gggttcggggccccaacaaagagaatttcaccga	CRISPR spacer
gggttcggggccccaacaaaaagaatttcactga	Protospacer
********************.**********.**

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP040883_2	2.1\|1722497\|26\|NZ_CP040883\|CRISPRCasFinder	1722497-1722522	26	MN369743	Streptomyces phage Tribute, complete genome	80738-80763	4	0.846
NZ_CP040883_2	2.1\|1722497\|26\|NZ_CP040883\|CRISPRCasFinder	1722497-1722522	26	MT310865	Streptomyces phage Bmoc, complete genome	78515-78540	4	0.846
NZ_CP040883_2	2.1\|1722497\|26\|NZ_CP040883\|CRISPRCasFinder	1722497-1722522	26	MH576968	Streptomyces phage Wofford, complete genome	80704-80729	4	0.846
NZ_CP040883_2	2.1\|1722497\|26\|NZ_CP040883\|CRISPRCasFinder	1722497-1722522	26	MF358542	Streptomyces phage Sushi23, complete genome	80852-80877	4	0.846
NZ_CP040883_2	2.1\|1722497\|26\|NZ_CP040883\|CRISPRCasFinder	1722497-1722522	26	MK494112	Streptomyces phage EGole, complete genome	81544-81569	4	0.846
NZ_CP040883_2	2.1\|1722497\|26\|NZ_CP040883\|CRISPRCasFinder	1722497-1722522	26	MF347639	Streptomyces phage Samisti12, complete genome	81875-81900	4	0.846
NZ_CP040883_2	2.1\|1722497\|26\|NZ_CP040883\|CRISPRCasFinder	1722497-1722522	26	NC_042011	Streptomyces phage Peebs, complete genome	80496-80521	4	0.846
NZ_CP040883_2	2.1\|1722497\|26\|NZ_CP040883\|CRISPRCasFinder	1722497-1722522	26	NZ_CP020749	Bacillus mycoides strain Gnyt1 plasmid unnamed6, complete sequence	9314-9339	5	0.808
NZ_CP040883_2	2.1\|1722497\|26\|NZ_CP040883\|CRISPRCasFinder	1722497-1722522	26	CP024687	Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-3-257K, complete sequence	200447-200472	5	0.808
NZ_CP040883_2	2.1\|1722497\|26\|NZ_CP040883\|CRISPRCasFinder	1722497-1722522	26	MF358541	Streptomyces phage Warpy, complete genome	80974-80999	5	0.808
NZ_CP040883_3	3.1\|2034043\|30\|NZ_CP040883\|CRISPRCasFinder	2034043-2034072	30	NZ_CP054613	Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence	1051845-1051874	6	0.8

1. spacer 2.1|1722497|26|NZ_CP040883|CRISPRCasFinder matches to MN369743 (Streptomyces phage Tribute, complete genome) position: , mismatch: 4, identity: 0.846

acctcaagctcatgtgttcctctttt	CRISPR spacer
ggctcaagctcctgtgttcctctctt	Protospacer
. ********* ***********.**

2. spacer 2.1|1722497|26|NZ_CP040883|CRISPRCasFinder matches to MT310865 (Streptomyces phage Bmoc, complete genome) position: , mismatch: 4, identity: 0.846

acctcaagctcatgtgttcctctttt	CRISPR spacer
cgctcaagctcctgtgttcctctctt	Protospacer
  ********* ***********.**

3. spacer 2.1|1722497|26|NZ_CP040883|CRISPRCasFinder matches to MH576968 (Streptomyces phage Wofford, complete genome) position: , mismatch: 4, identity: 0.846

acctcaagctcatgtgttcctctttt	CRISPR spacer
tgctcaagctcctgtgttcctcattt	Protospacer
  ********* ********** ***

4. spacer 2.1|1722497|26|NZ_CP040883|CRISPRCasFinder matches to MF358542 (Streptomyces phage Sushi23, complete genome) position: , mismatch: 4, identity: 0.846

acctcaagctcatgtgttcctctttt	CRISPR spacer
ggctcaagctcctgtgttcctctctt	Protospacer
. ********* ***********.**

5. spacer 2.1|1722497|26|NZ_CP040883|CRISPRCasFinder matches to MK494112 (Streptomyces phage EGole, complete genome) position: , mismatch: 4, identity: 0.846

acctcaagctcatgtgttcctctttt	CRISPR spacer
ggctcaagctcctgtgttcctctctt	Protospacer
. ********* ***********.**

6. spacer 2.1|1722497|26|NZ_CP040883|CRISPRCasFinder matches to MF347639 (Streptomyces phage Samisti12, complete genome) position: , mismatch: 4, identity: 0.846

acctcaagctcatgtgttcctctttt	CRISPR spacer
ggctcaagctcctgtgttcctctctt	Protospacer
. ********* ***********.**

7. spacer 2.1|1722497|26|NZ_CP040883|CRISPRCasFinder matches to NC_042011 (Streptomyces phage Peebs, complete genome) position: , mismatch: 4, identity: 0.846

acctcaagctcatgtgttcctctttt	CRISPR spacer
ggctcaagctcctgtgttcctctctt	Protospacer
. ********* ***********.**

8. spacer 2.1|1722497|26|NZ_CP040883|CRISPRCasFinder matches to NZ_CP020749 (Bacillus mycoides strain Gnyt1 plasmid unnamed6, complete sequence) position: , mismatch: 5, identity: 0.808

acctcaagctcatgtgttcctctttt	CRISPR spacer
acctcaagctcatgagttccttgata	Protospacer
************** ******.  *

9. spacer 2.1|1722497|26|NZ_CP040883|CRISPRCasFinder matches to CP024687 (Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-3-257K, complete sequence) position: , mismatch: 5, identity: 0.808

acctcaagctcatgtgttcctctttt	CRISPR spacer
acctcaagctcatgagttccttgata	Protospacer
************** ******.  *

10. spacer 2.1|1722497|26|NZ_CP040883|CRISPRCasFinder matches to MF358541 (Streptomyces phage Warpy, complete genome) position: , mismatch: 5, identity: 0.808

acctcaagctcatgtgttcctctttt	CRISPR spacer
ggttcaagctcctgtgttcctcattt	Protospacer
. .******** ********** ***

11. spacer 3.1|2034043|30|NZ_CP040883|CRISPRCasFinder matches to NZ_CP054613 (Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed4, complete sequence) position: , mismatch: 6, identity: 0.8

cttgagctttgctcaggcgttcctcttttt	CRISPR spacer
tttgctttttgctcaggcgttcctgttgtt	Protospacer
.***  .***************** ** **

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

968733 : 1041103

Staphylococcus_phage(28.57%)

terminase,protease,head,holin,portal,capsid,tRNA,tail,integrase

attL 958449:958465|attR 1042555:1042571

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
958449:958465	attL	NA	NA	NA	NA
WP_002484510.1\|968733_969780_-\|integrase	tyrosine-type recombinase/integrase	A0A1J0MFS3	Staphylococcus_phage	5.0e-53	36.3
WP_012088039.1\|969825_970557_-	hypothetical protein	NA	NA	NA	NA
WP_002446812.1\|970597_970972_-	hypothetical protein	NA	NA	NA	NA
WP_002446811.1\|971127_971463_-	helix-turn-helix transcriptional regulator	A0A2I6PEN2	Staphylococcus_phage	1.4e-28	58.9
WP_002446810.1\|971623_971815_+	helix-turn-helix transcriptional regulator	A0A2I6PEL6	Staphylococcus_phage	3.1e-17	66.7
WP_002446809.1\|971868_972192_+	DUF771 domain-containing protein	NA	NA	NA	NA
WP_002446808.1\|972207_972402_+	hypothetical protein	NA	NA	NA	NA
WP_002446807.1\|972549_973791_+	DEAD/DEAH box helicase family protein	A0A1B1P7L4	Bacillus_phage	6.9e-134	57.2
WP_002484586.1\|973793_974111_+	hypothetical protein	A0A2P0ZLA7	Lactobacillus_phage	3.7e-23	46.5
WP_002484599.1\|974103_974400_+	hypothetical protein	A0A1B1P7M6	Bacillus_phage	3.6e-25	58.2
WP_002495697.1\|974399_976211_+	AAA family ATPase	A0A1B1P7N0	Bacillus_phage	1.1e-164	57.4
WP_002484592.1\|976229_976436_+	hypothetical protein	NA	NA	NA	NA
WP_002484600.1\|976487_976970_+	DUF669 domain-containing protein	A0A2H4J1S8	uncultured_Caudovirales_phage	8.9e-21	38.4
WP_002484609.1\|977019_978738_+	hypothetical protein	A0A1B1P7M5	Bacillus_phage	1.3e-207	63.5
WP_002484590.1\|978751_979102_+	helix-turn-helix transcriptional regulator	A0A2H4IYG5	uncultured_Caudovirales_phage	4.8e-16	38.8
WP_002484612.1\|979132_979351_+	DUF3310 domain-containing protein	Q4ZC12	Staphylococcus_virus	1.9e-26	78.6
WP_002484605.1\|979357_980089_+	hypothetical protein	H9A0T0	Staphylococcus_phage	5.4e-62	49.2
WP_002484596.1\|980153_980474_+	phosphoribosyl-ATP diphosphatase	A0A2H4J2H9	uncultured_Caudovirales_phage	4.6e-42	81.6
WP_002484581.1\|980501_980969_-	hypothetical protein	A0A1W6JPR4	Staphylococcus_phage	3.5e-22	41.5
WP_002484606.1\|981036_981282_+	hypothetical protein	NA	NA	NA	NA
WP_002484603.1\|981359_981554_+	hypothetical protein	NA	NA	NA	NA
WP_002484601.1\|981583_983458_+	DNA primase	A0A1B1P7L5	Bacillus_phage	1.2e-211	58.0
WP_002484607.1\|983781_984273_+	DNA-directed RNA polymerase sigma-70 factor	S5MAA9	Brevibacillus_phage	2.6e-07	28.0
WP_002484574.1\|984476_985094_+	hypothetical protein	NA	NA	NA	NA
WP_002446790.1\|985375_985666_+	HNH endonuclease	D2XR61	Bacillus_phage	3.2e-18	42.2
WP_002491654.1\|985988_986327_+	hypothetical protein	D2XR14	Bacillus_phage	5.8e-11	39.4
WP_002484595.1\|986310_987945_+\|terminase	terminase large subunit	A0A0U4B089	Bacillus_phage	1.8e-182	56.6
WP_002484608.1\|987960_989097_+\|portal	phage portal protein	A0A0U4IIQ9	Bacillus_phage	4.0e-88	43.8
WP_002484598.1\|989096_989843_+\|protease	Clp protease ClpP	A0A2H4J8Y7	uncultured_Caudovirales_phage	6.4e-42	47.4
WP_002484575.1\|989867_991025_+\|capsid	phage major capsid protein	A0A0U4JIF4	Bacillus_phage	2.2e-97	51.7
WP_002484579.1\|991051_991360_+\|head,tail	phage head-tail connector protein	A0A2H4JF26	uncultured_Caudovirales_phage	1.5e-10	39.1
WP_002446783.1\|991331_991661_+\|head	phage head closure protein	NA	NA	NA	NA
WP_002446782.1\|991660_991999_+	hypothetical protein	NA	NA	NA	NA
WP_002484584.1\|991998_992436_+	hypothetical protein	NA	NA	NA	NA
WP_002484613.1\|992441_993146_+	hypothetical protein	NA	NA	NA	NA
WP_002446779.1\|993169_993520_+	hypothetical protein	NA	NA	NA	NA
WP_002446778.1\|993567_993780_+	hypothetical protein	NA	NA	NA	NA
WP_002504620.1\|993843_998025_+\|tail	phage tail tape measure protein	A0A2P0ZLF1	Lactobacillus_phage	1.9e-63	42.6
WP_002484577.1\|998027_998798_+	hypothetical protein	NA	NA	NA	NA
WP_002484585.1\|998794_1002250_+\|tail	phage tail protein	M1PRQ3	Streptococcus_phage	1.7e-20	24.0
WP_002484576.1\|1002270_1002681_+	hypothetical protein	A0A1I9KKA6	Lactobacillus_phage	4.3e-08	31.3
WP_002484582.1\|1002715_1002997_+	hypothetical protein	NA	NA	NA	NA
WP_002484580.1\|1002998_1003385_+\|holin	phage holin family protein	D7RWK5	Brochothrix_phage	9.3e-13	33.9
WP_002484578.1\|1003438_1004356_+	N-acetylmuramoyl-L-alanine amidase	A0A1W6JNM6	Staphylococcus_phage	4.9e-68	63.4
WP_012112670.1\|1004468_1005071_+	hypothetical protein	NA	NA	NA	NA
WP_002484587.1\|1005415_1005733_+	hypothetical protein	NA	NA	NA	NA
WP_001829860.1\|1006184_1007033_+\|protease	serine protease	A0A2H4PQN3	Staphylococcus_phage	3.5e-20	31.9
WP_002456347.1\|1007258_1008317_+	PTS transporter subunit IIC	NA	NA	NA	NA
WP_002440300.1\|1008555_1010013_+	ABC transporter substrate-binding protein/permease	NA	NA	NA	NA
WP_001829838.1\|1010005_1010728_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.6e-34	41.5
WP_064783702.1\|1011242_1011380_+	hypothetical protein	A0A146ICT8	Staphylococcus_phage	9.8e-10	73.8
WP_001829814.1\|1011589_1012720_+\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_001829836.1\|1012716_1013187_+\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
WP_002456349.1\|1013344_1013944_+	glucosamine-6-phosphate isomerase	NA	NA	NA	NA
WP_002468490.1\|1013967_1014147_+	hypothetical protein	NA	NA	NA	NA
WP_001829818.1\|1014302_1014707_+	hypothetical protein	NA	NA	NA	NA
WP_001829862.1\|1014891_1016277_+	class II fumarate hydratase	NA	NA	NA	NA
WP_001829804.1\|1016637_1017462_-	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_001829819.1\|1017620_1018754_+	GAF domain-containing sensor histidine kinase	NA	NA	NA	NA
WP_001829810.1\|1018746_1019370_+	response regulator transcription factor	A0A1V0SGR9	Hokovirus	5.2e-05	28.2
WP_001829807.1\|1019640_1020105_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002485606.1\|1020286_1021417_+	DUF445 domain-containing protein	NA	NA	NA	NA
WP_001829805.1\|1021489_1021834_+	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	5.8e-06	30.6
WP_001829843.1\|1022104_1023301_+	DNA repair exonuclease	NA	NA	NA	NA
WP_002456350.1\|1023290_1026230_+	AAA family ATPase	NA	NA	NA	NA
WP_002456351.1\|1026226_1027168_+	3'-5' exoribonuclease YhaM	NA	NA	NA	NA
WP_161375074.1\|1027342_1027444_+	type I toxin-antitoxin system Fst family toxin	NA	NA	NA	NA
WP_002456352.1\|1027593_1028571_-	foldase	NA	NA	NA	NA
WP_001829837.1\|1028772_1029333_-	DUF3267 domain-containing protein	NA	NA	NA	NA
WP_002456353.1\|1029498_1029870_-	YtxH domain-containing protein	NA	NA	NA	NA
WP_001829828.1\|1029946_1030372_-	HIT family protein	NA	NA	NA	NA
WP_001829855.1\|1030501_1031242_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	7.0e-25	28.4
WP_002456354.1\|1031234_1032458_+	ABC transporter permease	NA	NA	NA	NA
WP_001829861.1\|1032516_1033134_+	CadD family cadmium resistance transporter	NA	NA	NA	NA
WP_001829811.1\|1033695_1034199_-	signal transduction protein TRAP	NA	NA	NA	NA
WP_002456355.1\|1034491_1035553_+	uroporphyrinogen decarboxylase	NA	NA	NA	NA
WP_001829846.1\|1035629_1036553_+	ferrochelatase	NA	NA	NA	NA
WP_002469574.1\|1036696_1038094_+	protoporphyrinogen oxidase	NA	NA	NA	NA
WP_002456357.1\|1038229_1038784_+	serine hydrolase family protein	NA	NA	NA	NA
WP_002484688.1\|1040032_1041103_-\|integrase	site-specific integrase	A0A1J0MFS3	Staphylococcus_phage	1.6e-70	42.1
1042555:1042571	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1078445 : 1126668

Staphylococcus_phage(81.25%)

integrase,transposase,tRNA

attL 1067212:1067228|attR 1080018:1080034

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1067212:1067228	attL	NA	NA	NA	NA
WP_174168253.1\|1078445_1078940_-\|integrase	site-specific integrase	B7T092	Staphylococcus_virus	6.4e-67	76.1
WP_002456423.1\|1079098_1079311_+	hypothetical protein	A0A2H4JCA1	uncultured_Caudovirales_phage	7.3e-20	72.9
WP_002456424.1\|1079690_1080425_-	hypothetical protein	NA	NA	NA	NA
1080018:1080034	attR	NA	NA	NA	NA
WP_002456426.1\|1080951_1081239_-	hypothetical protein	A0A2H4JGN1	uncultured_Caudovirales_phage	5.5e-18	50.0
WP_002456427.1\|1081400_1082066_-	Ltp family lipoprotein	A0A2H4J5B8	uncultured_Caudovirales_phage	7.0e-08	41.8
WP_002456429.1\|1083316_1084741_+	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	6.6e-173	63.9
WP_001829851.1\|1084730_1085732_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	6.9e-92	50.2
WP_002457867.1\|1085728_1085977_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	6.5e-36	83.1
WP_002456430.1\|1086047_1086515_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	5.5e-44	57.4
WP_002456431.1\|1086501_1087287_+	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	2.0e-99	71.3
WP_002469572.1\|1087517_1089110_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	1.6e-268	83.6
WP_001829830.1\|1089479_1090679_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	4.1e-192	85.4
WP_002456434.1\|1090781_1091690_+	hypothetical protein	A0A2H4PQQ8	Staphylococcus_phage	1.8e-102	80.6
WP_002456435.1\|1091869_1092706_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	6.1e-110	68.6
WP_049385659.1\|1093008_1093146_+	hypothetical protein	A0A146ICT8	Staphylococcus_phage	1.8e-11	79.1
WP_104832471.1\|1093375_1094554_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	3.7e-60	37.0
WP_002484462.1\|1095032_1095386_-	CrcB family protein	NA	NA	NA	NA
WP_001830726.1\|1095382_1095748_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	4.1e-34	57.0
WP_002446728.1\|1095784_1096093_-	hypothetical protein	NA	NA	NA	NA
WP_002484454.1\|1096369_1097083_+	transaldolase	M1PR54	Cyanophage	7.0e-22	37.4
WP_002467846.1\|1097222_1097666_+	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	4.1e-20	43.5
WP_001830734.1\|1097652_1098096_-	competence protein ComK	NA	NA	NA	NA
WP_002484457.1\|1098101_1098581_-	sigma-70 family RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	9.1e-26	42.9
WP_002456441.1\|1098788_1099004_+	hypothetical protein	NA	NA	NA	NA
WP_001830727.1\|1099381_1100233_+	glucosaminidase domain-containing protein	A0A1J0MFB0	Staphylococcus_phage	1.0e-32	35.6
WP_002484471.1\|1100580_1102065_+	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	2.5e-13	65.6
WP_002494782.1\|1102500_1103544_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	8.9e-135	66.8
WP_002467848.1\|1103550_1104183_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.1e-87	77.6
WP_002484458.1\|1104195_1105377_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	5.7e-178	75.8
WP_002456446.1\|1105389_1105851_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.2e-59	84.2
WP_002484452.1\|1106108_1107110_-	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	5.8e-131	69.7
WP_002484455.1\|1107352_1108180_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_002484465.1\|1108669_1109086_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_001830894.1\|1109307_1109871_-	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	1.9e-67	66.5
WP_001830802.1\|1109867_1110821_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	3.3e-67	84.7
WP_001830884.1\|1110927_1112142_+	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	4.6e-183	83.7
WP_002484468.1\|1112430_1114848_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	87.3
WP_001830891.1\|1114873_1115185_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	4.1e-35	71.8
WP_002484464.1\|1115589_1126668_+	YSIRK signal domain/LPXTG anchor domain surface protein	A0A2H4PQU6	Staphylococcus_phage	3.2e-28	26.2

DBSCAN-SWA_3

1596096 : 1648751

Staphylococcus_phage(48.48%)

terminase,protease,head,holin,portal,capsid,tRNA,tail,plate,integrase

attL 1597334:1597393|attR 1628371:1628493

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002456552.1\|1596096_1596450_-	hypothetical protein	A0A1J0MF61	Staphylococcus_phage	2.2e-21	47.0
1597334:1597393	attL	NA	NA	NA	NA
WP_002457563.1\|1597642_1597855_-	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	6.4e-16	62.3
WP_002484791.1\|1598244_1598976_-	hypothetical protein	NA	NA	NA	NA
WP_002458418.1\|1598982_1599756_-	hypothetical protein	Q4ZAU0	Staphylococcus_virus	2.8e-48	41.4
WP_002458419.1\|1599934_1600852_-	N-acetylmuramoyl-L-alanine amidase	A0A1W6JNM6	Staphylococcus_phage	5.0e-65	56.1
WP_002484783.1\|1600891_1601287_-\|holin	phage holin family protein	A0A1S6KVE0	Staphylococcus_phage	1.7e-17	37.9
WP_002484785.1\|1601310_1602588_-\|plate	BppU family phage baseplate upper protein	A0A1J0MFQ3	Staphylococcus_phage	1.8e-124	52.2
WP_002458423.1\|1602605_1603622_-	SGNH/GDSL hydrolase family protein	A0A1J0MFI8	Staphylococcus_phage	1.9e-97	56.0
WP_002458424.1\|1603634_1604231_-	hypothetical protein	A0A1J0MFD6	Staphylococcus_phage	5.8e-54	49.1
WP_002484790.1\|1604214_1604436_-	hypothetical protein	A0A1J0MF94	Staphylococcus_phage	9.7e-07	64.1
WP_002458425.1\|1604422_1605601_-\|tail	phage tail protein	A0A1W6JQ67	Staphylococcus_phage	2.2e-60	32.1
WP_002458426.1\|1605613_1606438_-\|tail	phage tail family protein	A0A1D6Z283	Staphylococcus_phage	2.1e-46	37.6
WP_002484786.1\|1606439_1610930_-\|tail	phage tail tape measure protein	A0A075M036	Staphylococcus_phage	4.8e-217	46.8
WP_002484788.1\|1611102_1611453_-	hypothetical protein	NA	NA	NA	NA
WP_002458430.1\|1611476_1612136_-\|tail	tail protein	A0A059T7Y4	Listeria_phage	5.6e-26	39.6
WP_002484779.1\|1612147_1612537_-	hypothetical protein	Q4ZCL5	Staphylococcus_virus	9.1e-16	38.4
WP_002484776.1\|1612533_1612947_-	hypothetical protein	A0A059T5F3	Listeria_phage	7.9e-18	39.8
WP_002458432.1\|1612946_1613243_-\|head	phage head closure protein	G4KNQ4	Staphylococcus_phage	1.8e-08	32.2
WP_002458433.1\|1613295_1613634_-\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_002458434.1\|1613643_1613931_-	hypothetical protein	NA	NA	NA	NA
WP_002458435.1\|1613944_1615195_-\|capsid	phage major capsid protein	R9TQG7	Paenibacillus_phage	2.5e-67	37.8
WP_002484782.1\|1615187_1615832_-\|head,protease	HK97 family phage prohead protease	V5USG3	Enterococcus_phage	9.1e-21	38.5
WP_002458436.1\|1615821_1617048_-\|portal	phage portal protein	A0A290G4I4	Caldibacillus_phage	1.6e-58	40.1
WP_002458437.1\|1617062_1618778_-\|terminase	terminase large subunit	A0A290GJW3	Caldibacillus_phage	1.7e-207	60.1
WP_002458438.1\|1618770_1619172_-	hypothetical protein	R9TQ46	Paenibacillus_phage	1.4e-27	59.3
WP_002458439.1\|1619292_1619649_-	HNH endonuclease	A0A2K9VBV6	Staphylococcus_phage	1.3e-21	53.6
WP_002458440.1\|1619703_1620546_-	hypothetical protein	NA	NA	NA	NA
WP_002484781.1\|1620573_1621074_-	positive control factor	A0A0S2MVE1	Bacillus_phage	3.5e-12	31.2
WP_002457319.1\|1621248_1621473_+	hypothetical protein	NA	NA	NA	NA
WP_002457320.1\|1622143_1622443_-	hypothetical protein	NA	NA	NA	NA
WP_002504544.1\|1622493_1622841_-	hypothetical protein	NA	NA	NA	NA
WP_002457322.1\|1622846_1623749_-	DnaD domain protein	A0A1P8L6F0	Staphylococcus_phage	2.5e-53	52.8
WP_002457323.1\|1623778_1624174_-	single-stranded DNA-binding protein	Q4ZAD5	Staphylococcus_virus	4.1e-32	51.4
WP_002457324.1\|1624187_1624454_-	hypothetical protein	A0A2H4JAK6	uncultured_Caudovirales_phage	6.2e-16	57.1
WP_002457325.1\|1624516_1624708_-	DUF1270 family protein	NA	NA	NA	NA
WP_002457326.1\|1624722_1624932_-	hypothetical protein	A0A2H4JFX1	uncultured_Caudovirales_phage	1.3e-21	68.1
WP_002457327.1\|1624997_1625201_+	hypothetical protein	NA	NA	NA	NA
WP_002457328.1\|1625189_1625354_-	hypothetical protein	NA	NA	NA	NA
WP_002457329.1\|1625353_1625509_-	hypothetical protein	NA	NA	NA	NA
WP_002457330.1\|1625530_1625809_-	hypothetical protein	NA	NA	NA	NA
WP_002457331.1\|1625836_1626073_-	DUF739 family protein	A0A2I6PDH8	Staphylococcus_phage	8.7e-30	83.3
WP_002457332.1\|1626237_1626588_+	helix-turn-helix domain-containing protein	R9QTP6	Staphylococcus_phage	3.4e-22	50.0
WP_002457333.1\|1626757_1627129_+	hypothetical protein	NA	NA	NA	NA
WP_002457334.1\|1627171_1628296_+\|integrase	site-specific integrase	A0A0C5AN64	Paenibacillus_phage	1.9e-34	29.0
WP_001829492.1\|1628440_1629781_-	type I glutamate--ammonia ligase	NA	NA	NA	NA
1628371:1628493	attR	NA	NA	NA	NA
WP_001829488.1\|1629799_1630165_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_002456554.1\|1630645_1631884_-	methionine gamma-lyase family protein	NA	NA	NA	NA
WP_002456555.1\|1631899_1633150_-	GTPase HflX	NA	NA	NA	NA
WP_002456556.1\|1633250_1633727_+	glutathione peroxidase	Q70H87	Fowlpox_virus	1.1e-26	43.7
WP_001829517.1\|1633948_1634188_-	RNA chaperone Hfq	NA	NA	NA	NA
WP_002504492.1\|1634141_1635140_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_002456557.1\|1635151_1636078_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001832566.1\|1636301_1637975_-	glycerol-3-phosphate dehydrogenase/oxidase	NA	NA	NA	NA
WP_001829522.1\|1638151_1639651_-	glycerol kinase GlpK	NA	NA	NA	NA
WP_001829504.1\|1639804_1640629_-	aquaporin family protein	NA	NA	NA	NA
WP_002504493.1\|1641003_1641537_-	glycerol-3-phosphate responsive antiterminator	NA	NA	NA	NA
WP_002456559.1\|1641550_1643488_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	1.1e-61	30.6
WP_001832553.1\|1643502_1646124_-	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	3.8e-41	23.3
WP_001829480.1\|1646321_1646816_-	energy coupling factor transporter S component ThiW	NA	NA	NA	NA
WP_001829463.1\|1646839_1647205_-	YlbF family regulator	NA	NA	NA	NA
WP_002439565.1\|1647206_1648751_-\|tRNA	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	NA	NA	NA	NA

DBSCAN-SWA_4

1866223 : 1874693

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001831672.1\|1866223_1866790_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.0
WP_002504799.1\|1866789_1867821_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	2.8e-64	43.4
WP_001831721.1\|1867813_1869298_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	9.4e-45	31.9
WP_001831715.1\|1869276_1871466_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	8.7e-140	40.4
WP_001831727.1\|1871458_1872130_-	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_001831728.1\|1872131_1872392_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_001831723.1\|1872391_1873096_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	H8ZMN3	Synechococcus_phage	1.6e-47	42.5
WP_001831674.1\|1873096_1874224_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_001831735.1\|1874210_1874693_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	5.2e-21	43.3

DBSCAN-SWA_5

2109791 : 2120225

uncultured_Caudovirales_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001829596.1\|2109791_2110571_-	ATP-binding cassette domain-containing protein	W6JKT0	Anomala_cuprea_entomopoxvirus	5.1e-18	33.6
WP_002438903.1\|2110567_2111527_-	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	4.1e-17	100.0
WP_002438902.1\|2111510_2112485_-	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	5.9e-165	99.7
WP_002456931.1\|2112500_2112764_-	hypothetical protein	A0A2H4IYB4	uncultured_Caudovirales_phage	5.5e-17	100.0
WP_001829597.1\|2112738_2113707_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	3.9e-185	100.0
WP_001829582.1\|2113825_2115931_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	100.0
WP_001829589.1\|2115893_2116292_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	2.0e-71	100.0
WP_001829684.1\|2117046_2117922_+	DMT family transporter	NA	NA	NA	NA
WP_001832596.1\|2117935_2118436_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	1.1e-50	70.1
WP_002438897.1\|2118719_2120225_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	5.5e-61	34.0

DBSCAN-SWA_6

2141653 : 2152189

Staphylococcus_phage(22.22%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001830323.1\|2141653_2142805_-	anthranilate synthase component I family protein	A0A0B5J984	Pandoravirus	7.5e-26	39.6
WP_001830349.1\|2142794_2143382_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
WP_001830328.1\|2143678_2144350_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	4.1e-64	55.7
WP_001830341.1\|2144354_2144774_+	6-carboxytetrahydropterin synthase QueD	NA	NA	NA	NA
WP_001830330.1\|2144774_2145488_+	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	1.6e-55	44.8
WP_001830331.1\|2145590_2146190_+	hypothetical protein	NA	NA	NA	NA
WP_049361804.1\|2146557_2146695_+	hypothetical protein	A0A146ICT8	Staphylococcus_phage	2.3e-11	76.7
WP_001830329.1\|2147290_2147728_+	DM13 domain-containing protein	NA	NA	NA	NA
WP_001830332.1\|2147778_2148252_+	DoxX family protein	NA	NA	NA	NA
WP_001830352.1\|2148226_2148916_+	response regulator transcription factor	W8CYM9	Bacillus_phage	3.4e-34	35.2
WP_025987135.1\|2148918_2149971_+	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	2.0e-17	30.6
WP_001830351.1\|2150040_2151147_-	glycosyltransferase family 2 protein	A8CG95	Salmonella_phage	6.3e-62	43.2
WP_001830355.1\|2151349_2152189_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.2e-60	43.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP040883

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection