CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP053337	Lactobacillus paraplantarum strain CK401 chromosome, complete genome	3 crisprs	DinG,cas3,DEDDh,csa3,WYL	1	6
NZ_CP053341	Lactobacillus paraplantarum strain CK401 plasmid pCK401D, complete sequence	0 crisprs	NA	0	0
NZ_CP053339	Lactobacillus paraplantarum strain CK401 plasmid pCK401B, complete sequence	0 crisprs	NA	0	0
NZ_CP053342	Lactobacillus paraplantarum strain CK401 plasmid pCK401E, complete sequence	0 crisprs	NA	0	1
NZ_CP053338	Lactobacillus paraplantarum strain CK401 plasmid pCK401A, complete sequence	0 crisprs	NA	0	0
NZ_CP053340	Lactobacillus paraplantarum strain CK401 plasmid pCK401C, complete sequence	0 crisprs	NA	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP053337_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053337_1

488335-488421

Orphan

Consensus_repeat	Method
CTGTTCCCCGTGTATGCGGGGGTGAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP053337_1

>merge|NZ_CP053337|1|488335-488421|CRISPRCasFinder
CTGTTCCCCGTGTATGCGGGGGTGATCCCGTCATACCAGCCCTTAGCGCACATCAATTTCCCTGTTTCCCGTGTATGCGGGGGTGAT

>NZ_CP053337|1|1|488335-488421|CRISPRCasFinder
CTGTTCCCCGTGTATGCGGGGGTGAT	CCCGTCATACCAGCCCTTAGCGCACATCAATTTCC
CTGTTTCCCGTGTATGCGGGGGTGAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053337.1\|WP_033609479.1\|484820_485144_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053337.1\|WP_021731729.1\|490692_491049_-\|50S-ribosomal-protein-L20	unknown	unknown	gnl\|CDD\|179959
NZ_CP053337.1\|WP_003640278.1\|491301_491802_-\|translation-initiation-factor-IF-3	unknown	unknown	gnl\|CDD\|234582
NZ_CP053337.1\|WP_021731718.1\|479462_480098_-\|nicotinate-nucleotide-adenylyltransferase	unknown	unknown	gnl\|CDD\|234611
NZ_CP053337.1\|WP_003640274.1\|496705_497221_-\|transcriptional-repressor-NrdR	unknown	unknown	gnl\|CDD\|234774
NZ_CP053337.1\|WP_021731719.1\|480110_480425_-\|ribosome-assembly-RNA-binding-protein-YhbY	unknown	unknown	gnl\|CDD\|198171
NZ_CP053337.1\|WP_033609480.1\|486575_486923_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647
NZ_CP053337.1\|WP_033609485.1\|482765_483230_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053337.1\|WP_021731724.1\|485430_486180_-\|amino-acid-racemase	unknown	unknown	gnl\|CDD\|213495
NZ_CP053337.1\|WP_021731728.1\|490125_490437_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053337.1\|WP_003638526.1\|491085_491280_-\|50S-ribosomal-protein-L35	unknown	unknown	gnl\|CDD\|234676
NZ_CP053337.1\|WP_021731726.1\|487084_488152_+\|zinc-binding-alcohol-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|176214
NZ_CP053337.1\|WP_021731733.1\|497262_497856_-\|dephospho-CoA-kinase	unknown	unknown	gnl\|CDD\|234620
NZ_CP053337.1\|WP_021731723.1\|483233_484547_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|236882
NZ_CP053337.1\|WP_021731727.1\|488692_489955_+\|replication-associated-recombination-protein-A	unknown	unknown	gnl\|CDD\|237355
NZ_CP053337.1\|WP_021731732.1\|495280_496684_-\|DnaD-domain-protein	unknown	unknown	gnl\|CDD\|226138
NZ_CP053337.1\|WP_021731720.1\|480504_481641_-\|ribosome-biogenesis-GTPase-YqeH	unknown	unknown	gnl\|CDD\|237511
NZ_CP053337.1\|WP_021731721.1\|481637_482168_-\|YqeG-family-HAD-IIIA-type-phosphatase	unknown	unknown	gnl\|CDD\|225090
NZ_CP053337.1\|WP_021731731.1\|494341_495277_-\|primosomal-protein-DnaI	unknown	unknown	gnl\|CDD\|236353
NZ_CP053337.1\|WP_056988310.1\|492045_494010_-\|threonine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234752

Protein	Function_ID	Function_description	E-value
NZ_CP053337.1\|WP_056988310.1\|492045_494010_-\|threonine--tRNA-ligase	gnl\|CDD\|234752	PRK00413, thrS, threonyl-tRNA synthetase; Reviewed.	0
NZ_CP053337.1\|WP_003640278.1\|491301_491802_-\|translation-initiation-factor-IF-3	gnl\|CDD\|234582	PRK00028, infC, translation initiation factor IF-3; Reviewed.	1.53157e-90
NZ_CP053337.1\|WP_021731718.1\|479462_480098_-\|nicotinate-nucleotide-adenylyltransferase	gnl\|CDD\|234611	PRK00071, nadD, nicotinate-nucleotide adenylyltransferase.	2.61183e-89
NZ_CP053337.1\|WP_021731729.1\|490692_491049_-\|50S-ribosomal-protein-L20	gnl\|CDD\|179959	PRK05185, rplT, 50S ribosomal protein L20; Provisional.	5.89656e-62
NZ_CP053337.1\|WP_021731719.1\|480110_480425_-\|ribosome-assembly-RNA-binding-protein-YhbY	gnl\|CDD\|198171	smart01103, CRS1_YhbY, Escherichia coli YhbY is associated with pre-50S ribosomal subunits, which implies a function in ribosome assembly. GFP fused to a single-domain CRM protein from maize localises to the nucleolus, suggesting that an analogous activity may have been retained in plants. A CRM domain containing protein in plant chloroplasts has been shown to function in group I and II intron splicing. In vitro experiments with an isolated maize CRM domain have shown it to have RNA binding activity. These and other results suggest that the CRM domain evolved in the context of ribosome function prior to the divergence of Archaea and Bacteria, that this function has been maintained in extant prokaryotes, and that the domain was recruited to serve as an RNA binding module during the evolution of plant genomes. YhbY has a fold similar to that of the C-terminal domain of translation initiation factor 3 (IF3C), which binds to 16S rRNA in the 30S ribosome.	8.74273e-30
NZ_CP053337.1\|WP_021731720.1\|480504_481641_-\|ribosome-biogenesis-GTPase-YqeH	gnl\|CDD\|237511	PRK13796, PRK13796, GTPase YqeH; Provisional.	0
NZ_CP053337.1\|WP_021731724.1\|485430_486180_-\|amino-acid-racemase	gnl\|CDD\|213495	TIGR00035, Aspartate_racemase, aspartate racemase. Asparate racemases and some close homologs of unknown function are related to the more common glutamate racemases, but form a distinct evolutionary branch. This model identifies members of the aspartate racemase-related subset of amino acid racemases. [Energy metabolism, Amino acids and amines].	3.14122e-61
NZ_CP053337.1\|WP_021731732.1\|495280_496684_-\|DnaD-domain-protein	gnl\|CDD\|226138	COG3611, DnaB, Replication initiation/membrane attachment protein [DNA replication, recombination, and repair].	6.79263e-45
NZ_CP053337.1\|WP_003638526.1\|491085_491280_-\|50S-ribosomal-protein-L35	gnl\|CDD\|234676	PRK00172, rpmI, 50S ribosomal protein L35; Reviewed.	1.32915e-16
NZ_CP053337.1\|WP_021731726.1\|487084_488152_+\|zinc-binding-alcohol-dehydrogenase-family-protein	gnl\|CDD\|176214	cd08252, AL_MDR, Arginate lyase and other MDR family members. This group contains a structure identified as an arginate lyase. Other members are identified quinone reductases, alginate lyases, and other proteins related to the zinc-dependent dehydrogenases/reductases. QOR catalyzes the conversion of a quinone and NAD(P)H to a hydroquinone and NAD(P+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR acts in the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	0
NZ_CP053337.1\|WP_021731733.1\|497262_497856_-\|dephospho-CoA-kinase	gnl\|CDD\|234620	PRK00081, coaE, dephospho-CoA kinase; Reviewed.	5.15386e-83
NZ_CP053337.1\|WP_021731723.1\|483233_484547_+\|glycosyltransferase	gnl\|CDD\|236882	PRK11204, PRK11204, N-glycosyltransferase; Provisional.	3.63544e-107
NZ_CP053337.1\|WP_021731727.1\|488692_489955_+\|replication-associated-recombination-protein-A	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	1.13158e-179
NZ_CP053337.1\|WP_033609480.1\|486575_486923_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	5.62301e-40
NZ_CP053337.1\|WP_021731721.1\|481637_482168_-\|YqeG-family-HAD-IIIA-type-phosphatase	gnl\|CDD\|225090	COG2179, COG2179, Predicted hydrolase of the HAD superfamily [General function prediction only].	8.71681e-67
NZ_CP053337.1\|WP_021731731.1\|494341_495277_-\|primosomal-protein-DnaI	gnl\|CDD\|236353	PRK08939, PRK08939, primosomal protein DnaI; Reviewed.	2.33305e-168
NZ_CP053337.1\|WP_003640274.1\|496705_497221_-\|transcriptional-repressor-NrdR	gnl\|CDD\|234774	PRK00464, nrdR, transcriptional repressor NrdR.	4.13817e-88

>NZ_CP053337.1|WP_021731726.1|487084_488152_+|zinc-binding-alcohol-dehydrogenase-family-protein
MHAIGFTDHLPIENPASLQDVTITKPTPHGHDILVQIQAVAVNPVDVGVRKAGHEHLTRPKILGWDATGIVTAVGKAVTLFQPGDWVFYAGSFNRPGCDSAYHLVDERLVGHAPKTLTPAACAAMPLTSLTAYEALFEQLHISFDPAKPNSQKHNQTILIINGAGGVGSIATQLAKLTGLTVISSASRPESITWTQQHGADLVVNHRHDLVREVHALGIKDVDYILGLSDLNSHWDEMCALIKPGGHIASITENRRPIDLKKLTKKRRTFAWEWMYSKSYYHTADMISQHYILDTIANLLDHDLLKSTLSQTLQPINALNLRQAHQLIEQRHMIGKVVIEGWNDLTPYCGSGNLL
>NZ_CP053337.1|WP_033609480.1|486575_486923_-|helix-turn-helix-transcriptional-regulator
MQRQIYDCAAGCPVESTLQVIAGKWKSVILYHLLTTGTCRFSTLQKRLPGCSRRMLARQLQEMLQDGVIAKRVYPVVPPKTEYWVTPFGQTLKPVIMAMEAWGRQYNSVNGNIIS
>NZ_CP053337.1|WP_021731724.1|485430_486180_-|amino-acid-racemase
MENCFGIIGGMGTMATEDFVHTVNRLTVTHRDQDYLNYVVLNDAQIPDRTAYILDHNCTNPLPSLKADVRLLNRLGAKFIVMTCNTAHYFIPALTAITNVPILNMPALAVEAACQLQQPRPLRIGILATTGTLKSQLYQQLIRSNGHMPVVPTEQQQAQVMALIYEDIKQHDYVDRVKFHGLIDQLLNAADCDAVILGCTELSVAQDAVPYGSERVIDAQYELARVTVQCAQAAKPTMILQRQQSMNGY
>NZ_CP053337.1|WP_033609479.1|484820_485144_+|hypothetical-protein
MKCPTIVRHIHGRNAPFPAHTGDPYFNKESGQPLIALLDANLAGPVEPFATYIEDVTSYKIYIEKGEKMFELLEAIINIIKYLGMAIVFGFLAYALIYIMIGVFTMN
>NZ_CP053337.1|WP_021731723.1|483233_484547_+|glycosyltransferase
MEIMQTLKPFESIWNFVLLLLVSYPILGAFAWFVGVLCYQLIYRHRHTDDVEFKELAPAEQPLITIMIPAHNEEVMIEHTIDYLMTSLNYTNYEVLVTDDGSTDKTPEILARLQDKYAKLRVVTIRKNQGKAHAFNVGVGFARGEFILSNDADSIPEPDALWKYMSYFMGEEHANTAAVTANMDVQNRSTIIAKSQTVEFSSIVGVIKRSQVSALGNMYAYSGANTMYRRDALIDVGLFRQDRATEDISIAWDHQLNGWTTVFSPDILFYMNVPETLKALYHQRKRWAKGGTEVLLTNFRRVMSHPGKYLKQWAFITDQTLSIIWSLFFFVSTLIFLFSLISFFFTGNYERVYHMFCMAFIFVTFEMFAGLLQLLSALIVDDRGKKFKYLIFMPLYMLVYWQVNALALVMTLIPAVKTILGYGSGTWVSPVRKHHME
>NZ_CP053337.1|WP_033609485.1|482765_483230_+|hypothetical-protein
MQQYVTDKYFTKGHWWTKIWQTLVAIIGWICVAIPVYWTISSTLLANNPRFIHAWKYEEGKTLFYFFDRFFIFAFILIAIIVIISTIHNNHRVKQHISKERQYDEEQLAIRKRRLNNFYTTRFGQETFRQHVKHYTVDPEQNLDVHEIHKLYED
>NZ_CP053337.1|WP_021731721.1|481637_482168_-|YqeG-family-HAD-IIIA-type-phosphatase
MIKQFKPTWMIPAIYNVTPAQLRAQGIKAVFTDLDNTLIAWNNPDGTPELKKWLHALQDAGIPLVVVSNNSEDRIAKALTSLELPFVSRSLKPLPIGITKARRDLGLQPNEVVMVGDQYITDMWAAHLAGVSSILVKPIVTTDAWNTRINRFFERFIKLRLAHVYPEMHFQEDLNK
>NZ_CP053337.1|WP_021731720.1|480504_481641_-|ribosome-biogenesis-GTPase-YqeH
MSETSEETLYCIGCGAAIQTTDPKAAGYTPNSALQKSLASDVQDLYCQRCFRLRHYNEIVPVGLTDDDFRHLLATIRDANALVVYVVDIFDLNGSIIPGLQRFVGDNPVLLVGNKEDVLPRQLRRTKLREWMNQQVRAQGIKPVDVALTSAKKGHSIDELLAMIEKYRRGRDVYVVGVTNVGKSTLINRIIANNTGLKDLITTSRFPGTTLDKIEIPLDDGHMMVDTPGIIHPEQMAHVLSGDDLKLVSPQREIRPKGFQLGNGQTLFLGGVARLDIVDTMKPTGTVYVDNNLTLHRTRTENADNFYTKHVGELITPPTGDAVADFPALVRHEFKVTEISDIVFEGLGWVTVAADTRVAAWAPQGVAVLTRPAMINKR
>NZ_CP053337.1|WP_021731719.1|480110_480425_-|ribosome-assembly-RNA-binding-protein-YhbY
MENLRGKQKHYLRGEAHHMRPLFAVGKNGLTDDWLMQLTGALDKRELIKVNILQNADVTTAEVKAAIEQHTAITVVQTIGRVLVLYLPASHEEDRHYSLEVAKL
>NZ_CP053337.1|WP_021731718.1|479462_480098_-|nicotinate-nucleotide-adenylyltransferase
MQTVNQTATKVLTETVTAIPHRRVGILGGTFNPPHLGHLIMAQQVGDQLGLDEVRFMPDAQPPHVDEKKTIAIEDRANMVQEAIVDNPLFRLETAEITRGGKSYTYETMKLLKAQHPDTQYYFIIGGDMVDYLHTWYHIDDLVKLVTFVGIKRTGYPTTSQYPVIWVDAPLIDISSTQIRQKISHGHSVRYLVPETVAAYIKEHHLYEQND
>NZ_CP053337.1|WP_021731727.1|488692_489955_+|replication-associated-recombination-protein-A
MAFKTPLADQMRPQSLDQMVGQQDLLKSGQPLRQIIDQHVNIPLILWGPPGTGKTSLAQIIASQDDYPFVAFNASTENKAQLTKAIAQYPNQSFVLLIDEIHRMTKTLQDFLLPYLENGHVMLIGSTTENPIMSIVPAIRSRCQIFEFQPLSDTDIEIALRRAVTDIYELTDDQVDTQALNLIAISADGDLRIALNILETLHATDQHQITVAAVQNFAKQQHFSYDRKATKHYDYLSAYSDSMAGSDTDAALYYLTILLKNDDLPSVVRRLREIPYTYIGLANPEQVTQIVVAANQAEKIGMPKAKYPLMFATMLMCISPKSGSFDQSWEKLDQDTQNPSQHPMPRGLRDMHYKHSEEITGGGLINNPFQMPHQIAQQNYMPKGLAGRRYYFPKDNENERKLGAQYLKLHRFIYDEDYHE
>NZ_CP053337.1|WP_021731728.1|490125_490437_-|hypothetical-protein
MATVLPKAVKVWMGANILQIEFDNGEFRYLRTHFIDDYISAWSPKKGKGKRRNLWLMPSWEWLGANARIEPDGTVVLFEKDVYTAQELWHNSVMRIDLVSGVH
>NZ_CP053337.1|WP_021731729.1|490692_491049_-|50S-ribosomal-protein-L20
MARVKGGTVTRKRRKRILKLAKGYRGAKHIQFKVAKDQVMKSYEYAFRDRRRRKSDFRRLWIARINAAARINDISYSQLMHGLKLANVDVNRKMLADLAVNDADAFKALVDTAKKALA
>NZ_CP053337.1|WP_003638526.1|491085_491280_-|50S-ribosomal-protein-L35
MPKQKTNRAAAKRFKVTAKGKIKSANAFTSHRFHGKTKKQRRQLRGTAIIEKPMVKTYHKLLQK
>NZ_CP053337.1|WP_003640278.1|491301_491802_-|translation-initiation-factor-IF-3
MVNDGIRAREVRLIASDGEQLGVKSRQEAMQIAEDASLDLVLVAPKAKPPVARIMDYGKYRFEQQKKDREARKKQKVVSIKEVRLSPAIDTNDFNTKLKHAEKFLSKGDKVRVSIRFKGRAITHKDIGRQVLNRMIEATKEFSTVEAYPKMDGRSMFLVLAPKTDK
>NZ_CP053337.1|WP_056988310.1|492045_494010_-|threonine--tRNA-ligase
MASINVKFPDGAEKQFDAGVTTEAIAKSISPSLAKRSVAGKFNDQIVDYRQPLTTDGSIEIIAADSEDGLNVLRQTAAQVLANAVKQLFPNIHFGSGEGNANGFFFDTDNPDEDGKQVSEDDLEAISDKMAAIIKQDLPIEREVLSKADALALVGDNPYQQDLVNERAAANNDQVVVYKQGDFVDLSDGAQLASTGKVKVFKLLSVAGAYWQGKSSNPMLQRIYGTAFLKQKDLDADLKRRQEARERDHRVIGNELDLFFVDPKVGNGLPYWMPNGATIRRQIERYIIDKEVANGYQHVYTPVLANLDVYKQSGHWEHYREDMFPPMDMGDGEQLELRPMNCPSHIQIYNHHIRSYRELPLRIAELGMMHRYEKSGALTGLSRVREMTLNDGHTFVAMDQIEEEFKKILSLMVEVYEDFDISDYRFRLSYRDPENKEKYFDDDAMWERSQKMLKSAMDDMGLDYFEAEGEAAFYGPKLDVQTKTALGGEETLSTIQLDFLLPERFDLKYVGADGEEHRPVMIHRGLVSTMERFVAYLTEIYKGAFPTWLAPKQVTIIPVNNGAHGAYAETVRRRLAAEGVRVSIDDRNEKMGYKIRESQTKKVPYLLVVGDQEVANGSVSVRKYGEERTESEAVDMFIGAITQEIKHYSRGASK
>NZ_CP053337.1|WP_021731731.1|494341_495277_-|primosomal-protein-DnaI
MENISETLRTLMNRKNLNHRYEALMTAVYQDPDVRQFLAAHQNELSSDALERSAAKLYEFCEEKRKIARHEPTQAPGYQPALVMSNHLIDIAYQPTPQLQKQQAAHELQQRVRSISMPKNIQTADLKTYDQDGDRATALMAALDFIDAYTQAPKRFHRGLYLYGSFGVGKTYLLGGMANALAAKGFNTTLIHFPSFAVEMKRSISNNTSADKVDAIKRAPILMIDDIGADSSSTWIRDDVLGVILEYRMQEELPTCFSSNFSMQELQDGYLTLSQKGDEEPVKAQRIMQRVRYLASEIEMVGRNRRLNPDA
>NZ_CP053337.1|WP_021731732.1|495280_496684_-|DnaD-domain-protein
MPNDKPLTPKTGLVVPQAPALSAAQQAVLAELYLPLMGPLAYSLYAALRSLQSSENELSNRRSHAELLGILNVDLPAVLAARRKLEATGLLRSYYQQDELGVVYIYQLQAPLLALQFFADDLLSVLLLDTVGELRYQQLASDFSAQPIDLTAAKDVTANILDVFHVDSQKVTTPPLSVQKVRAQLAANEPAEDHSPVLSDDDFDWQLLGQILKQNYVDLKQVASSRQLIITESRVYGISEIEMAKLISEVASLTTGQFDENQLKLLIARRYERPAVPSQQVATEVSVATSAIKDTKTSAQLSTAEQQLVTYAKQVAPYEFLTALKQEKHGFVTSGENRLVHDLIGRGVLPNAVINMVIYYLLQNRELAALNRNLLETVANDWQQHGITTPEAALIYLRQRKQPKSTPTRRKNNRPTRKEIMPRWAQQQQQTERGKQPAQTGKQITAAQRKQLADRLAKLETNSEKED
>NZ_CP053337.1|WP_003640274.1|496705_497221_-|transcriptional-repressor-NrdR
MQCPHCHHNGSRVVDSRPTDDGRVIRRRRECENCGFRFTTFERVEATPLLVIKKNGAREEFNREKVLRGIIRSAEKRPVSMETMTGVVDDVENKVRSLGENEISSQVIGEYVMEQLADIDEISYIRFASVYRQFKDMHVFLNELQDMMERDKVKLAKPSAKTTHAPKRKKD
>NZ_CP053337.1|WP_021731733.1|497262_497856_-|dephospho-CoA-kinase
MTKLIGLTGGIATGKSTVSKLLAAKLPIVDADKIAWQVEGPGQPTTQKIAAYFGQQAVLADGQLNRPWLGQLVFNDPQALQALTAITRLPIQYAMFEAIVAANQHQPAAIILDIPLLFESGWQHICDQVLVVTAPPTVVLQRLMARNHLSQQAAQARIDSQMPLAQKVAQADVVIDNGANIDKTEAAVLKWLKTITN

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Crispr_ID: NZ_CP053337_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053337_2

2272126-2272304

Orphan

Consensus_repeat	Method
TTTCAAAATTGTTCTAAGGTGAC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP053337_2

>merge|NZ_CP053337|2|2272126-2272304|CRISPRCasFinder
TTTCAAAATTGTTCTAAGGTGACGACCTTAGATGTTAGTAATTGGACTGTTCCAGTAATTACTAGTTTAGCCAGCACCTTTCAGAATTGTTCTAAGGTGACAACACTGAATCTTAGTGGTTGGGATACGTCCGACGTCACTACCCTAGCTAATACCTTTCAGAATTGTTCAAGTCTCAC

>NZ_CP053337|2|2|2272126-2272304|CRISPRCasFinder
TTTCAAAATTGTTCTAAGGTGAC	GACCTTAGATGTTAGTAATTGGACTGTTCCAGTAATTACTAGTTTAGCCAGCACC
TTTCAGAATTGTTCTAAGGTGAC	AACACTGAATCTTAGTGGTTGGGATACGTCCGACGTCACTACCCTAGCTAATACC
TTTCAGAATTGTTCAAGTCTCAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053337.1\|WP_021729951.1\|2263411_2264050_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP053337.1\|WP_021729962.1\|2275674_2281773_+\|KxYKxGKxW-signal-peptide-domain-containing-protein	unknown	unknown	gnl\|CDD\|375451
NZ_CP053337.1\|WP_021729961.1\|2274194_2275241_+\|DUF916-and-DUF3324-domain-containing-protein	unknown	unknown	gnl\|CDD\|371730
NZ_CP053337.1\|WP_021729965.1\|2282350_2282767_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133398
NZ_CP053337.1\|WP_021729970.1\|2287147_2288143_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NZ_CP053337.1\|WP_171284644.1\|2264148_2265159_+\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|187538
NZ_CP053337.1\|WP_021729947.1\|2256521_2260013_-\|MucBP-domain-containing-protein	unknown	unknown	gnl\|CDD\|380191
NZ_CP053337.1\|WP_021729960.1\|2273557_2274121_+\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
NZ_CP053337.1\|WP_021729967.1\|2283948_2285355_+\|6-phospho-beta-glucosidase	unknown	unknown	gnl\|CDD\|133432
NZ_CP053337.1\|WP_021729948.1\|2260481_2261945_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|180854
NZ_CP053337.1\|WP_021729964.1\|2282040_2282373_-\|YrdB-family-protein	unknown	unknown	gnl\|CDD\|378498
NZ_CP053337.1\|WP_021729966.1\|2282905_2283868_+\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380509
NZ_CP053337.1\|WP_021729954.1\|2266465_2268070_+\|sodium:proton-antiporter	unknown	unknown	gnl\|CDD\|223104
NZ_CP053337.1\|WP_021729953.1\|2265297_2266122_+\|NAD(+)-diphosphatase	unknown	unknown	gnl\|CDD\|234699
NZ_CP053337.1\|WP_171284646.1\|2285591_2286137_+\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
NZ_CP053337.1\|WP_021729956.1\|2268299_2269154_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP053337.1\|WP_021729957.1\|2269272_2270121_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|235135
NZ_CP053337.1\|WP_021729946.1\|2255837_2256305_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|153102
NZ_CP053337.1\|WP_103127203.1\|2270782_2270992_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053337.1\|WP_021729969.1\|2286162_2286852_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|226674

Protein	Function_ID	Function_description	E-value
NZ_CP053337.1\|WP_021729951.1\|2263411_2264050_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	6.5314e-08
NZ_CP053337.1\|WP_021729962.1\|2275674_2281773_+\|KxYKxGKxW-signal-peptide-domain-containing-protein	gnl\|CDD\|375451	pfam17966, Mub_B2, Mub B2-like domain. This entry corresponds to the Mub B2 domain. This domain is related to the Mub B1 domain pfam17965. This domain may be involved in mucin binding. This domain is often found associated with the related pfam17965 in bacterial cell surface proteins.	1.30315e-13
NZ_CP053337.1\|WP_021729957.1\|2269272_2270121_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|235135	PRK03592, PRK03592, haloalkane dehalogenase; Provisional.	2.44486e-25
NZ_CP053337.1\|WP_021729970.1\|2287147_2288143_-\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	3.28426e-78
NZ_CP053337.1\|WP_171284644.1\|2264148_2265159_+\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|187538	cd05227, AR_SDR_e, aldehyde reductase, extended (e) SDRs. This subgroup contains aldehyde reductase of the extended SDR-type and related proteins. Aldehyde reductase I (aka carbonyl reductase) is an NADP-binding SDR; it has an NADP-binding motif consensus that is slightly different from the canonical SDR form and lacks the Asn of the extended SDR active site tetrad. Aldehyde reductase I catalyzes the NADP-dependent reduction of ethyl 4-chloro-3-oxobutanoate to ethyl (R)-4-chloro-3-hydroxybutanoate. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	3.31513e-68
NZ_CP053337.1\|WP_021729947.1\|2256521_2260013_-\|MucBP-domain-containing-protein	gnl\|CDD\|380191	NF033187, internalin_J, class 1 internalin InlJ. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface-anchored proteins with an N-terminal signal peptide, leucine-rich repeats, and a C-terminal LPXTG processing and cell surface anchoring site. See PMID:17764999 for a general discussion of internalins. Members of this family are internalin J (InlJ).	1.40759e-43
NZ_CP053337.1\|WP_021729960.1\|2273557_2274121_+\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	1.44697e-12
NZ_CP053337.1\|WP_021729967.1\|2283948_2285355_+\|6-phospho-beta-glucosidase	gnl\|CDD\|133432	cd05296, GH4_P_beta_glucosidase, Glycoside Hydrolases Family 4; Phospho-beta-glucosidase. Some bacteria simultaneously translocate and phosphorylate disaccharides via the phosphoenolpyruvate-dependent phosphotransferase system (PEP-PTS). After translocation, these phospho-disaccharides may be hydrolyzed by the GH4 glycoside hydrolases such as the phospho-beta-glucosidases. Other organisms (such as archaea and Thermotoga maritima ) lack the PEP-PTS system, but have several enzymes normally associated with the PEP-PTS operon. The 6-phospho-beta-glucosidase from Thermotoga maritima hydrolylzes cellobiose 6-phosphate (6P) into glucose-6P and glucose, in an NAD+ and Mn2+ dependent fashion. The Escherichia coli 6-phospho-beta-glucosidase (also called celF) hydrolyzes a variety of phospho-beta-glucosides including cellobiose-6P, salicin-6P, arbutin-6P, and gentobiose-6P. Phospho-beta-glucosidases are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0
NZ_CP053337.1\|WP_021729948.1\|2260481_2261945_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|180854	PRK07121, PRK07121, FAD-binding protein.	1.13364e-63
NZ_CP053337.1\|WP_021729964.1\|2282040_2282373_-\|YrdB-family-protein	gnl\|CDD\|378498	pfam10823, DUF2568, Protein of unknown function (DUF2568). One member in this family is annotated as yrdB which is part of a four gene operon however currently no function is known.	7.39461e-08
NZ_CP053337.1\|WP_021729966.1\|2282905_2283868_+\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|380509	cd06286, PBP1_CcpB-like, ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species. This group includes the ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species. Catabolite control protein B (CcpB) is 30% identical in sequence to CcpA which functions as the major transcriptional regulator of carbon catabolite repression/regulation (CCR), a process in which enzymes necessary for the metabolism of alternative sugars are inhibited in the presence of glucose. Like CcpA, the DNA-binding protein CcpB exerts its catabolite-repressing effect by a mechanism dependent on the presence of HPr(Ser-P), the small phosphocarrier proteins of the phosphoenolpyruvate-sugar phosphotransferase system, but with a less significant degree.	7.32152e-76
NZ_CP053337.1\|WP_021729954.1\|2266465_2268070_+\|sodium:proton-antiporter	gnl\|CDD\|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	5.25301e-41
NZ_CP053337.1\|WP_021729961.1\|2274194_2275241_+\|DUF916-and-DUF3324-domain-containing-protein	gnl\|CDD\|371730	pfam11797, DUF3324, Protein of unknown function C-terminal (DUF3324). This family consists of several hypothetical bacterial proteins of unknown function.	8.20529e-46
NZ_CP053337.1\|WP_171284646.1\|2285591_2286137_+\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	1.45165e-52
NZ_CP053337.1\|WP_021729956.1\|2268299_2269154_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	5.27209e-53
NZ_CP053337.1\|WP_021729953.1\|2265297_2266122_+\|NAD(+)-diphosphatase	gnl\|CDD\|234699	PRK00241, nudC, NAD(+) diphosphatase.	1.55478e-56
NZ_CP053337.1\|WP_021729969.1\|2286162_2286852_+\|SDR-family-oxidoreductase	gnl\|CDD\|226674	COG4221, COG4221, Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only].	5.7911e-85
NZ_CP053337.1\|WP_021729946.1\|2255837_2256305_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|153102	cd01043, DPS, DPS protein, ferritin-like diiron-binding domain. DPS (DNA Protecting protein under Starved conditions) domain is a member of a broad superfamily of ferritin-like diiron-carboxylate proteins. Some DPS proteins nonspecifically bind DNA, protecting it from cleavage caused by reactive oxygen species such as the hydroxyl radicals produced during oxidation of Fe(II) by hydrogen peroxide. These proteins assemble into dodecameric structures, some form DPS-DNA co-crystalline complexes, and possess iron and H2O2 detoxification capabilities. Expression of DPS is induced by oxidative or nutritional stress, including metal ion starvation. Members of the DPS family are homopolymers formed by 12 four-helix bundle subunits that assemble with 23 symmetry into a hollow shell. The DPS ferroxidase site is unusual in that it is not located in a four-helix bundle as in ferritin, but is shared by 2-fold symmetry-related subunits providing the iron ligands. Many DPS sequences (e.g., E. coli) display an N-terminal extension of variable length that contains two or three positively charged lysine residues that extends into the solvent and is thought to play an important role in the stabilization of the complex with DNA. DPS Listeria Flp, Bacillus anthracis Dlp-1 and Dlp-2, and Helicobacter pylori HP-NAP which lack the N-terminal extension, do not bind DNA. DPS proteins from Helicobacter pylori, Treponema pallidum, and Borrelia burgdorferi are highly immunogenic.	2.71854e-46
NZ_CP053337.1\|WP_021729965.1\|2282350_2282767_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133398	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators. Helix-turn-helix (HTH) heavy metal resistance transcription regulators (HMRTR): MerR1 (mercury), CueR (copper), CadR (cadmium), PbrR (lead), ZntR (zinc), and other related proteins. These transcription regulators mediate responses to heavy metal stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	1.79405e-20

>NZ_CP053337.1|WP_103127203.1|2270782_2270992_+|hypothetical-protein
MSTRTSRAYRKNDRQTNQGSSWRGYLPQTDEQACRWLLVIMGLLLLILLLMAAYYGNKCERYQHSVLHE
>NZ_CP053337.1|WP_021729957.1|2269272_2270121_+|alpha/beta-fold-hydrolase
MKFATVKVQGLEMFYREAGSPDKPVFLLLHGFPTASHLFRNLMPMLAKDFHVIAPDFIGFGQSAAPAHDTFDYTFENLTNYVEVFLTVMNIDKFYMYVFDYGAPIGFGIAVKYPERILGIVSQNGNIYQEGLGAKWADREAYWQHPTPALRKSYQAAFKPATIIGQYKGGEQPNSVSPDGYSLDIFYTSLPDYAERQSDLIFDYQNNVKNYPVFQKYVRTYQPEIIAAWGKNDLSFVYQGAQAFAKDDPNVDVHLLNGGHFVLETHWQEIGQLILDKWGQKD
>NZ_CP053337.1|WP_021729956.1|2268299_2269154_-|LysR-family-transcriptional-regulator
MNTDTLKMFITIAQAGSISAAAQQLGYAQSNISTKLQQLERDLNTRLFYRNNRGIVLTATGQQLLQRASQIVQLTDRTITDIQHPNDVRGRLRLGTLQAAASTFLPPILSHYHQHYPKVTLTIQTGTTLTNTQAVLNYQVDGAIIGGTVNDDALISIPLMQEPLCLITATSSMADIHHTPILVFPVGCAYRKTLERWLDSQQITLHYPVEFDYLNAIIASVSAGLGMSILPTRVVQPYVDAGVLNAVTLPAPFATLPVTFIYRQDTVMSAPFDHFITAIRHYHD
>NZ_CP053337.1|WP_021729954.1|2266465_2268070_+|sodium:proton-antiporter
MALLISTAVLVVAALVSIVTNRQLLPRLSVNYVSMLIGALIAVVPFLNGLVEQFNSEVFIGLIVAPLLYFEGQNTRLNLVGRHVREIISLTVGMVVLCAVAAGIGTQLLAGVGLPLAFILAAISTPTDATATESVTMGRILPRREQTSLKLESLFNDASGIILLNMATLWYVNGYINYSQTLWDFVYAAGGGIVFGGAISGLIVYVRQKMLRSRLNFINNTYNNGTPLKIIYVMTPFVLYFGAEALGVSGIIAVVVAGLVHNAEGERSSLANPQLASDIHQLVGLMSDILNSIVFIVLGIMLLRTALDRSVSYDGSLIWIVIGIALYLANLFARYGYVRLVHHLARREAWIFALGGIHGAVTFALAFTVAETQVKTADFNLVLMSESLLIILSLLVPTIIFRWLLPSIPTDPTATVRIAGIRQQMIDAGVNRVQQMTIPQEFKDAVAFDLRSQNGHTSMRQFIAEWRRMVQHPEYTANQMRELMVIYRQVFQTERDYLQQQYDETHAISEDLFNQLYHEITMAEMVVLEYGVKD
>NZ_CP053337.1|WP_021729953.1|2265297_2266122_+|NAD(+)-diphosphatase
MFQDIQPHVLKNQNDQQRSPRPGDYVLIGRQQQVLLINGTLPKYEAVTADWAFTADQYQYLLAVDQAAFFWVDVEAEAKDQYTVGTTRDFRNLTPAWLAFSSATAAHLAWWYDTKRFCGHCGQPLHPGATERSLVCAACGQTIYPTIMPAIIVGVTNGDKILMTKFLSGYNHFSLISGYTEIGETFEDTVRREVFEEVGLEVHNIRYFGSQPWAPSHSLLAGYFADLNENVAIELETDELAKAQWFQRDQIPHNDTNTSLTWTMIEAFRHHQEK
>NZ_CP053337.1|WP_171284644.1|2264148_2265159_+|NAD-dependent-epimerase/dehydratase-family-protein
MKKVIVTGGTGFVAGWVIVEFLKAGYQVATSIRSTSKISQLTETFEKVVTPQELANLSFFEADLTQSAGWVENMRGAQGVIHVASPMGNGTQTVDELVSVAKNGALTVLRAAKKAGVKRIVMTSSQAASTPEHGSTAVLDESFWTDIHNPDLDPYRISKVESERAAWQYARANQLALTTILPGAIFGPILSSRAVSSDRILGQLLHGLPMIPHVPLEISDVRYLAHLHRLAFESDVAIDQRYLAASQTMSMADVARCYQNEFPEKKIKIRLLPNWGTKVVARFVPSMRSLVPMLNRQSRHTTRAAEHDLGWIQHRPEETVIDTAHSLIDFGLDQSV
>NZ_CP053337.1|WP_021729951.1|2263411_2264050_-|TetR/AcrR-family-transcriptional-regulator
MDPKKELIIKFNHIILIQGFTRFSMVDLAKMANISRAKLYIYFKNKDEIVAAVVERHLRFTQKYPVPSQAQADNLLPTMLNAWLLMGSTTTLFEQELQQTYPQLARRLNQAITKYFADVQQYYQQAQTANLIIDTVSTEYLMFQNKLNIRGILQQVQLGELTLEQGEHYLKESSTFQLQAMFVAPVPQPTPEVLALEKTIINEYYDTYSLTN
>NZ_CP053337.1|WP_021729948.1|2260481_2261945_-|FAD-dependent-oxidoreductase
MTLTEHTSYDIVVVGTGAAGTAAALEAAQHGATVLLLEKGRHTGGSSNYTEGLFAVDSYLQQAQNIHVSATDVLKEEVDYSKYRADSRIWRQYLDDSANTVQWLKDQGVEYEGVQAMGAGEATWHIYKGMGQAVLHDALQPKAQSLGVEMLTSTTVTALHQADDGTITGVTIQDAGTKETQAIATSAVILATGGYLNNPEMMASLTHYDTRRLIPVSSGKGTGDGLQLAWDAGAQKYGTGMAMLFGGYLKDPAEPSFKYMASQMETAAGQQPLLWLNEHGERFVDEAVVYNFSYAGNALYTQNQVFSILDQGVIDRMAQDGNFMGLGVYVRRGEKMTKLQSEIDAAVTAKKPFIFKADTIDELAAKMHLPVDQVTKSVQTYNQYCDNGQDADFGKNPDYLVKVATGPYYGFELNVGAFCTMGGLKVTTANEVLDTTGNTIQGLYAAGNDAAGLTGDTYGPNMPGTCVGYAFYSGRNSGRHAASYANH
>NZ_CP053337.1|WP_021729947.1|2256521_2260013_-|MucBP-domain-containing-protein
MNKQKIITNNPPKWHLITGIAATILAGVILTNQQAFAASEPSTLTMPTTNQLTTTSPLSGQQVVLATSANSQPTTSLVASDAQATSASSDNHTSVVTADQSNRPTSTASSANSTTSVTTTTASNAPSNATTATVAAGSNAGTASATTHTSDGPTNISPDLPTTIASTGQNSDGSTASPSTTLASPASISTTSSTVPAASSSTATAPINATISTSVAPASGATSVAGASNAAISSSAAADQPANTTSISTELVSAGSGTTHPATTNTAPSSSVPVTSAVNSATSSAMSATTNFITSAVNSIAASTVSEVASAASAESAATSSTSATAPASTGTPTTFQITSAVNSIAASTYSEYAAAASAEAASAGTVAETPATSVGTIIPTTAPSESIDTWMPNKHLQTAVLRELQALKLPDHQFNSVNDITKDDMQLLTKFYGNDTYIDGQTAYSLEGLQYATNLTTIWLNNGLNALGGYYNGDVTDISPLAGLTKLTVLNIQHNRVSDLSPIAHLTNLEELDVAYNHIADLSIFKDLPNLKTTTYVGQTILEPLVYVDQNTASATLKNYFYLPNGQQATFKSQAAILKPIQLTPDGQFYYRFYFNGAGKAVNGDLSNVVPDGQGGLTFNQLVPQIPGFTGDANGQFSVGGINVNVMPNERNFYLVAQGLDGTAPVFHVFQPYVLAAKAAPVTVQHLDRTGVALREPEELTGLVGEDYQSTPADIPNYTHVDTQGAPQGTFSAEPQTVAYVYEKTAGAPVTVSYQDEQGQTLKPDTTCNGFTGDAYTTDPLTIDGYDLVKTPTNATGTFTSEPQHVIYVYTKQIPQPVTASYQDETGQTLKPDITHTGEIGTAYQTEALVIPGYDLVKTTGDATGTFTKEPQHVVYVYTKQIPQPVTASYQDAAGQTLKPDITHTGEIGATYQTEALVIPGYDLVKTTGDATGTFTKEPQHVVYVYAKQSVLPVTVSYQDADGKPIHADVILAGDFGQNYQTEQLAIPGYVFSKVTGPISGTFGATAQHVIYAYTPEPSVPGTPAPKPEPEPQPVPEPIPQPGLTPVPKPQPSPVPVPTPGSTSNSSSAPQAKTPLPPDIAGLPDTKPASVPATTASEPIVPATASAQPNAKTPAQTNSTTAGQLPQTNEQSEHDATIWGLLAALFAGLGWLGLAAKFKKHE
>NZ_CP053337.1|WP_021729946.1|2255837_2256305_-|DNA-starvation/stationary-phase-protection-protein
MKYTKTKEVLNQLVADLSQMSMIIHQTHWYMRGPNFLKLHPLMDEFMAEIDSQLDVISERLIALDGSPYSTLKEMTENTKIQDWPGEWDKTTPERLAHLVDGYRYLENLYQHGIEVSDVEKDFSTQDIFIGLKTAIEKKIWMIQAELGAAPEIDK
>NZ_CP053337.1|WP_021729960.1|2273557_2274121_+|WxL-domain-containing-protein
MKKFVFGLMISAGLLGATTVVANADTSTGDVTFTGGTLSMSVDTTNLAFGSNAITSSNATLDTTTTPTVTVSDLRGTSAGWTLTVAQGQQFNTATDGTGSALTNAALTVAGTESDSAVTNGSTTLVPGTTETAGAAGTVASAKNGTGNGDSTVTFSDSKLVVPGETTKLATGYTTTLTWNLSVTPGN
>NZ_CP053337.1|WP_021729961.1|2274194_2275241_+|DUF916-and-DUF3324-domain-containing-protein
MQKRLQCILGILLAGVVSLLMMGQAAAADQGVGFEITPVQSSSQVDKRLSYFDLKLKPRQTQIVAVKIHNTASAPITINIGIAKATTNINGVVEYKHTNNRSANLPYDISKLVTTDEPQVKLAKGQIKTVKFQIKMPAQSYQGILAGGITFLKKATATDTKKAVAVNNQYAYTEAVILHGSKDLTTNQLTMNKIAVKQINGRNVINFPLVNHTAAYLNKVQTNIKIYHRGGSKVVYHQKLANGQMAPNSIYKLPLRTGEKALAAGKYTAVVKVTSKKQHWQFKQNFVITQGQADTLNKTAVLNQGPNWWLYIGIGLLLLLLIVLVIWYIRRKQKKIKALEKQLAEKDK
>NZ_CP053337.1|WP_021729962.1|2275674_2281773_+|KxYKxGKxW-signal-peptide-domain-containing-protein
MQKRRLQQARLVEKRTYKMYKKGRLWLVAGLSTLTIGTGLAQLQVKADTTSTATSQTETTEVTGTSATLTTKATVSTSTASTESDTATKQNDSSDGTQTTSTDSNNNVATTSANSVSVAAEGDASSTTSHANTATKSSVANASAATTASTAADATTSSSTKTSGVAISETNPDTTATLIKTRTKTNVAETVSVASFSAAIASPSSTSRAAVTTVATVNSATKTYDGKTDTPNRYTVTLADGTKAPADWAATSTANVYTVTDLADVDTAKFSSEIGTYTIALSTTGITKLSEANNSADITAANVVTGTLTIEQAPVPSAIITIGSASINYGDATPSAYTITVPSQYKVPSAWTLASSATDGTTNTYMIASDSGDIVVPTATESGTYQLTLSNQGLVALQQANPNDAITADAIITGQLVIAAHDLITMGATTVMVNKTLSVVQATINSRSLVVPADWTISYDDTQTDAIVYNVPIAYTTYSEVVNSGVVGKYTITLTDAAMTTLSDLNSTTFDSTTVGDGVVLVKTSTAVILSPANYGAQASVETPISVLTISHARTRGIDLSYGQALYLILPLLNISQSETAVNNLTEYIIVPSGFKVATTASNGAAQVATDPVSTLTAAIETMMTQNNVTYQGLVVTQLTDYNDRQTFQVHFDQTSVYNGGSFSTLKYTLLPVIAVQSSGVTSGLIGNQVSSPDSAVVYVTDDPNETDGSYSLSLQNYTNIDRVADALGIADAVTIGSGFTDYLYHYTLSAKTITDTYQLVGNDGAALGTVTYTGDSGATYVPMTKLPTTITQDGVTYYLNTNTVASTQNYSGDENTVYTVTYQRYVTTSTDATARITIAPASKVYDNDATTDPSSYTVYLPTEYVAPSNWTIDDTAVVVSGTTAYHVSTNYLDTTTIDQNVGTYAVTLNAAGMAALAAANPNLLIAGNVNVGGTLTITKRPVTIALPDTILWANGQEQNIIPVITGVVAGQTIGYTLTSGLTDPGTKMITVTLTSAAVNNNYEITNPASGELTVGAVTVVYNYGYQAADGTFKLTSTISGTATHGVNINATDYLNYTTSDTAAAHNKIGYTLQPGSTGYQADGTLTDVGGQVVYTYLANTEKITVVYVDQDQNNATLKRVPLSGSFSTSVNYTTANDIEAYEELGYVLVSDQVPTSIRFDQDTEQTYYVYLTHGTTTVTVDHPGSLTVSDLTTTSQRIINYVYADQTPTGLDNVIQTVGYTRTAIVDAVDGTLLSYGNWTTSATGGYPVVVSPIITGYTADTATVAAAMPASVGEVMTKTVIYTVNPETIKIQFIDETTGNQVLATVELRGNYGDSANYTATADIAKYEKLGYELASSDLPNQLTYNQDDPTYRITLVHRRVTVSVDHPGQPGQPIDTNYPGGPKYPADTGRDSLQQTVTRTIMYQYATGKLAAAAVNQSVTFERTATFDMVTGKQLIYSDWVVAPGQTASLAVVTSPTITGYQASAAEVGAITVTSQSELQPVVITYTAKPEVASIVFVDVTSGDTLATRLVTGDYDTVSDYSPASQIAAYKSLGYQLTSNNVPITGISFDQDDVMKVYTVKLTHQLTTVTPTKPGKPGQPIDPTNPDGPKYPVGTGIEDLTTRSKRIINYVYGDGQNAAPTVAQTVIFHRTATFDQVTKKVTYTDWDTAESIVTGAYATIDSPVITGYTPSAVRVDGITVKAGDADVQQTVVYQANIETAMVTYIDVTVGHQLGASVTLTGLFGTQADYQPASVIAQYVKAGYVLMSNDYPSMGAVFNQDGVVQRYTVYLAHNKLAITDQDQLTKTVTQTVHYQDQSGQMLQADTIRALTFTRSGIEDAVTGVATYRDWEPTVLNFTALTAPTIAKYYALTATTQAVTITADSVDDVQTLTYALDNLTPTEPTKPIEPTKPVEPLKPLKPVKPAKPTGADDLLKPAQSTTPAKLVHLLQPTKPTTIVKADHVTTSNQLSALEPSQMAITSRANAVKATPIIKAASEATVQTNKTRVATSRQLPQTSESRRSELMTEILGVTLATLLLGFGELKRKHYEK
>NZ_CP053337.1|WP_021729964.1|2282040_2282373_-|YrdB-family-protein
MIKLIHASIRCLLEMTTIILFLISGLRTASWQRITILLTLLLLILFWSRYMAPLSASRWPSHRRLLVECLLFGSTIILTYSLINPIWASVYAVIAIINTTSEHLITTPSL
>NZ_CP053337.1|WP_021729965.1|2282350_2282767_-|MerR-family-transcriptional-regulator
MNTAAFCHHVHTTRDTLRYYEQIHLLVPKRTNNRYRQYDAADQQTFQLIRQLQRAGLTLTEIKQVLSLRQQSVTPSCHDETLLFIQHKASEFYHQATFFQQLASLADQLADALEHDESLKFQQLLSHLGGTDDQTNSC
>NZ_CP053337.1|WP_021729966.1|2282905_2283868_+|LacI-family-DNA-binding-transcriptional-regulator
MATIFDVAKLAQTSKSTVSRVVSGHGYVSAPVRKRVLAAMHQVNYVPNQLARQLKAQRTKTIGFLVNEYAPVMGDLINYFTQIAQSDGYRVNMYQTTNAADELHVLNQLMTHELDAVYIAVRHNRWDKIEPYTKYGPIATWQRIDSNEIYSSYIDHYPLYLQILTYLVNQGYTRIGHVLNNKRASNTQARLHAIAAFKRKYPQIDQEWQQAHQHQQHAGEQAALTWLQTPNPPQVVVLYADYVAAEFIATLRLHGKRVPEDCRVFGFDNSEFGRLMAITTVDAQLQGQAQNAYTYLINRIQQTSRPYQQLTPRLIFRSSC
>NZ_CP053337.1|WP_021729967.1|2283948_2285355_+|6-phospho-beta-glucosidase
MSHDALKLVTIGGGSSYTPELIEGYIKRREQLPIKEIWLVDIEAGMEKLKIVGAMAQRMVKAAGLDWEVHLTLDRQAALKDADFVSTQFRVGRLPARIKDERIPNYYGLIGQETNGAGGIFKAFRTVPVILDIVADMKRLCPQAWLINFTNPSGMITEAIRTYGHWDRVIGLCNVPVMAMLSEPELIGKTLDQLTYKFAGIDHFHWHRVWDESGQEVTMTIIDKLFGDNDAGLPTNIFDVPFFKDQLAAMRMIPCGYHRYYYRQEEMTAHGLAEYRENKTRAQQVTQIEEELFELYRDPELDYKPKQLAERGGAHYSDAACEAIASIYRDKKTHMVVSTLNQGSVPDLPSDHVVEVSAQIGAAGAVPMAFGHFQPAERGWLQLMKNMELVIVEAAVTGDYGLALQAFTMNPLIPSGATAKRVLDELLIAHQAYLPQFADKIQALIAAGIMVQDTVAAELSEVTQVVSD
>NZ_CP053337.1|WP_171284646.1|2285591_2286137_+|sugar-O-acetyltransferase
MREGDIIKPKYLDQAYLQAIQPIVDANQQRIQQLNTTHQPSKMRQLLAAITGQSIDDSVEVRVPLWTDYGRNLKIGNRVFINDNVQITDLGGIELADDVLIGPGAMLLSVNHPLDPAKRHAVEVQPIHIGRNAWIGAGAKVLAGVTVGENAVVGAGAVVTKSVLANTVVAGVPAKVIKTID
>NZ_CP053337.1|WP_021729969.1|2286162_2286852_+|SDR-family-oxidoreductase
MSIDNKVVVITGASSGIGAATAKLLAAKGAKVVLGARREDRLQALSQTIGDNAFYQVTDVTDRQQVRALIDLAVAKFGRVDVLYNNAGTMPQGNLSDRDYDKWQMMLNVNIMGVLNGIGKVLPIMQKQHDGLIIATDSVAGHVVYPASAVYNGTKYAVRAIMEGLRQEEKGHGIRSTIVSPGAVRTELVNTIGNTQIQAGISELMNADDSQGLALNPEDIANAVLFAID
>NZ_CP053337.1|WP_021729970.1|2287147_2288143_-|iron-ABC-transporter-permease
MTIHRRVCTWSVCLAGCILVLALINLSTGTMAIGLPALFQIISGHGAATDTLVLFNFRLPRIILALVVGWALALAGNVLQTITNNPMADPSLLGINNGAGLAVMLLIISAGTNASLTFSLPIVALLGAWLSTALIFLLANQPQRGISSKRLLLVGVALSGCFSALMVLMTLKLSPDNYQFVMNWLAGSLWGTDWAYIGWALPWLVAGSIILLIQLPVLDAFTLGTTTAQTLGLNLKHQQLGLISVAAMLAGVSVAISGGISFIGLITPNLARRIVGSRQRYQLPLAGLLGSTLLLAADTLGKLITTTTELPAGVLVALIGAPYFIYLLVRG

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Crispr_ID: NZ_CP053337_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053337_3

2809442-2809530

Orphan

Consensus_repeat	Method
CCAACCACTGCACCTGGTACTGGTGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP053337_3

>merge|NZ_CP053337|3|2809442-2809530|CRISPRCasFinder
CCAACCACTGCACCTGGTACTGGTGACAATGGTAATAACGGTGGCGGAACCATCACGACGGCACCAACCACCGCACCTGGTACTGGTGA

>NZ_CP053337|3|3|2809442-2809530|CRISPRCasFinder
CCAACCACTGCACCTGGTACTGGTGA	CAATGGTAATAACGGTGGCGGAACCATCACGACGGCA
CCAACCACCGCACCTGGTACTGGTGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053337.1\|WP_021732654.1\|2812554_2812827_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053337.1\|WP_003642771.1\|2812020_2812506_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NZ_CP053337.1\|WP_171284656.1\|2817095_2818490_+\|virulence-protein	unknown	unknown	gnl\|CDD\|227832
NZ_CP053337.1\|WP_089197950.1\|2816295_2817096_+\|bifunctional-DNA-primase/polymerase	unknown	unknown	gnl\|CDD\|214927
NZ_CP053337.1\|WP_021732660.1\|2805391_2805532_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053337.1\|WP_021732666.1\|2796565_2797918_+\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
NZ_CP053337.1\|WP_171284655.1\|2813567_2814725_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP053337.1\|WP_021732667.1\|2795487_2796345_+\|sugar-uptake-protein	unknown	unknown	gnl\|CDD\|284268
NZ_CP053337.1\|WP_021732669.1\|2792264_2793788_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP053337.1\|WP_027822981.1\|2815600_2815783_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378935
NZ_CP053337.1\|WP_027823047.1\|2816051_2816282_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053337.1\|WP_021732653.1\|2812850_2813084_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053337.1\|WP_050480186.1\|2814774_2815425_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188
NZ_CP053337.1\|WP_021732663.1\|2801143_2802721_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340855
NZ_CP053337.1\|WP_021732659.1\|2805895_2806039_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053337.1\|WP_021732662.1\|2802692_2804456_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP053337.1\|WP_021732664.1\|2799131_2801126_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213222
NZ_CP053337.1\|WP_021732668.1\|2794070_2795252_+\|class-I-SAM-dependent-rRNA-methyltransferase	unknown	unknown	gnl\|CDD\|224017
NZ_CP053337.1\|WP_021732665.1\|2798257_2798449_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053337.1\|WP_021732655.1\|2809990_2811967_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274008

Protein	Function_ID	Function_description	E-value
NZ_CP053337.1\|WP_027822981.1\|2815600_2815783_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	0.000523229
NZ_CP053337.1\|WP_003642771.1\|2812020_2812506_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	2.33211e-10
NZ_CP053337.1\|WP_171284656.1\|2817095_2818490_+\|virulence-protein	gnl\|CDD\|227832	COG5545, COG5545, Predicted P-loop ATPase and inactivated derivatives [General function prediction only].	7.30066e-66
NZ_CP053337.1\|WP_089197950.1\|2816295_2817096_+\|bifunctional-DNA-primase/polymerase	gnl\|CDD\|214927	smart00943, Prim-Pol, Bifunctional DNA primase/polymerase, N-terminal. Members of this family adopt a structure consisting of a core of antiparallel beta sheets. They are found in various bacterial hypothetical proteins, and have been shown to harbour both primase and polymerase activities.	2.57303e-37
NZ_CP053337.1\|WP_021732666.1\|2796565_2797918_+\|glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
NZ_CP053337.1\|WP_171284655.1\|2813567_2814725_-\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	7.05412e-42
NZ_CP053337.1\|WP_021732667.1\|2795487_2796345_+\|sugar-uptake-protein	gnl\|CDD\|284268	pfam06800, Sugar_transport, Sugar transport protein. This is a family of bacterial sugar transporters approximately 300 residues long. Members include glucose uptake proteins, ribose transport proteins, and several putative and hypothetical membrane proteins probably involved in sugar transport across bacterial membranes. These members are transmembrane proteins which are usually 5+5 duplications. This model recognizes a set of five TMs,.	1.52302e-115
NZ_CP053337.1\|WP_021732669.1\|2792264_2793788_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.38526e-61
NZ_CP053337.1\|WP_050480186.1\|2814774_2815425_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	2.24654e-08
NZ_CP053337.1\|WP_021732663.1\|2801143_2802721_+\|glycosyltransferase	gnl\|CDD\|340855	cd04949, GT4_GtfA-like, accessory Sec system glycosyltransferase GtfA and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.	6.99409e-74
NZ_CP053337.1\|WP_021732662.1\|2802692_2804456_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	3.96927e-145
NZ_CP053337.1\|WP_021732664.1\|2799131_2801126_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	9.13162e-100
NZ_CP053337.1\|WP_021732668.1\|2794070_2795252_+\|class-I-SAM-dependent-rRNA-methyltransferase	gnl\|CDD\|224017	COG1092, COG1092, Predicted SAM-dependent methyltransferases [General function prediction only].	1.2666e-76
NZ_CP053337.1\|WP_021732655.1\|2809990_2811967_+\|hypothetical-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	8.33869e-10

>NZ_CP053337.1|WP_021732659.1|2805895_2806039_+|hypothetical-protein
MSFFNDFHVLPGTHTSSYTSSVSNDIFGGFHSFILNLIPAIKGLFSK
>NZ_CP053337.1|WP_021732660.1|2805391_2805532_+|hypothetical-protein
MSFFTDLHFLPGTHTSSYTSSVSNDIFGGFHSFILNLIPAIKSLFS
>NZ_CP053337.1|WP_021732662.1|2802692_2804456_+|ABC-transporter-ATP-binding-protein
METHITSSANQPHAKYGTRDLLRLIMTHAHPKKGLFIVGILLSFVATICSLGITLMLKEFIDAFNHGTSGQLLGRLAVVIVVQLFASVASSFLLSYTGVDAVSTLRSALWQHIVDLPIPYFDHNRTGELSSRVVNDTSTIFELISSQFSNAINGIISIIGSLTLMLLLNFRLTIIILIVVPLMAVIIVPMGQVLARISKAIQKETANLNSAAVQMIGQNRLVKAMVAEKALKQQGSDQVDRIKGFSVRQIKLISVLNPVLNIMLLAAIFIIIVYGGILVQTKALTIGSLVAFLMYAVQMISPLSSVTGLVTALQQTVGATERIDNILDSPEEDKRLSGETLTTIDTVDFDHVDFGYEHDKPVLKDVDLTIHRGERIALIGESGSGKTTLVSLLEAYYTPTRGDLDVNGQAMDSYTIPSIRNQIGYVSQEVDLMPGTIRDNLLLGSTQAVPDEQLSALLTQVGLADWLAELSAGLDTDVGERGLNVSGGQRQRLAIVRALVREPSLLILDEATASLDNQNQERVTQLLATLPADLTTITIVHRLNQIEAYPRILFMEDGCITGDGDHESLLATHERYRDFYRLQYQHG
>NZ_CP053337.1|WP_021732663.1|2801143_2802721_+|glycosyltransferase
MYFFITSKIDSTPSAIELAMIQRQKLFTKHRVPALIVTRNFVRDLHQNMHQIGYDDEFQVNMYDYFQGTTNYEGQPLTAANYPRVTGETLERVSANEFDVIQREQRQKALMLNAQGNIDYVDILNPQGAVSRRDYYDTRGFLTVAQYFDDKQNIVLEQHCNLQQQPVLETFFRPNEKQQPVATHQRLLNYHGHNYEFEDWDQLTAFFLDALNTEYGGHGTMIVDRSDAGMNPIVKMTTLARKYEFLHSNFTLDPLDVVNSPIVPYTQIGLDHANQMAGLIMSTQEECDDMTNHIHNVIPTLAIPVGSVSDEQLATRPVDFGDRTAGKVIAVARLSAEKNLEQLIKAVAYVHEKQSNVTLDIYGYGDSWTGFKEENRLRALVSSQHWQSFITFKGFERDLTPVYNQAQLMVLTSQYEGFNLGILEGLSHGVPVVAYDIKYGPATMINDGQNGRLITPNNLVELGKVILALLQNPKQLAQMSERAYGNSSRFSEAMIWQRWNDQVVQPDIQAMRGVTTNGNTYHVIG
>NZ_CP053337.1|WP_021732664.1|2799131_2801126_+|ATP-binding-cassette-domain-containing-protein
MSFLELHDIRKAYTLNHQENVILKGINLNFERGEFISILGESGGGKSTLMNIIGGLDHHYDGDVLLDGQSLRSMNVRQMDRYRRETIGFIFQNFNLVSYLTVLDNVMLSLKMTKMSRGQQVQQAQDLLKRVGLEQQTHQYPNELSGGQKQRVAIARALASDPDIIIADEPTGALDSENTQEVMDILYSIAAEGKLVITVTHSQEVADYGTRIVHLDDGQIHDELVIGAPFDVVDKQPTRYRTLGFRQMFRMSMQHMRRMWLRYLLIIFGSSIGISSIVVMLGLGSGIQNYMNHQITSQVNPTAVQVSKKTGKVSTSARKKATSAAAYKAAVNQEQVTAAKNAEVTTANAKQLAAIKHVKSAKLGYYTSTQANYQKTTVTASLQTDNPTILSKTIKNGSRPGTDQVLIGRKLAKKMMGKKHYQKALHKKLTVKLTTVNRKNQSVTVKQTLTVSGITGSDDTSVVVLPQTVKKMLAAKNVAYRPNFAIVQIDKLAHVKQVEHNIKAIKGTNKKQQYNYTGIGDLIDSLNTYIRLATNVLTGVAGIALLVSAIMIIVVLYVSVSERTREIGVLRALGARKRDISHLFFAEALTIGVLAAIMGLLFGEGWQFLGNMAIYSLIKYPIVRISGAAMLGGITVSVVISLLAALAPAHMAARLDPVESLSHE
>NZ_CP053337.1|WP_021732665.1|2798257_2798449_+|hypothetical-protein
MRKLNIIESIIIVVGLLVFWLGSEVTVINQQLPWLQFVGLIVVFVTGLADAIYRVVTKRSFFK
>NZ_CP053337.1|WP_021732666.1|2796565_2797918_+|glucose-6-phosphate-isomerase
MAHISFDSSNLTKFVHDNELGEMQAMVTAADKELREGTGAGNDFRGWLNLPTDYDKEEFARIKTAAKKIQGDSDVLVVIGIGGSYLGARAAIEFLHETFWSSLSREDRKFPQVVFAGNSISSSYVNDLIHLIGDRDFSVNIISKSGTTTEPSIAFRVFKERLIAKYGEEAAKGRIYATTDRKRGALKQEADAEGYETFVIPDDVGGRFTVLTPVGLLPIAVSGGDIDSLMKGAADAQNEYKDADLTKNEAYQYAAYRNILYRKGYTTEILENYEPNMAMFSEWWKQLMGESEGKDQKGIYPSSANFTTDLHSLGQYIQEGRRNLMETVVKVDNATSDVDIPKETENLDGLKYLEGKTMAQVNTKAFEGVIMAHVDGGVPNMVVNIPSQDAYTLGYTMFFFEAAVAISGYLNGINPFNQPGVEAYKNNMFALLGKPGYEELTKKLTARLSD
>NZ_CP053337.1|WP_021732667.1|2795487_2796345_+|sugar-uptake-protein
MGILIALIPAIAWGSIGLISGRMGGTARQQTLGMTMGALVFGLALWAVEQPTLTSKIWLIGIVSGLFWSIGQGQQFTSMKAVGISRTTPISTGMQLVANALAGVLLFNEWHGNMYWIGSVSVIVLIAGAVLTSLTDKTDPNRSASENWGVGIRALILSTIGYAGYTIVVHYGNVNAQAVVMPQAVGMLLGALIWSFKDKPWVVKATYRNIVTGLVWGVGNLFMFMAMAQIGQAVAYSLSQMGIVISTFGSIYLLGEHKTKREMVYVVIGSILVIVGGIALSLMKA
>NZ_CP053337.1|WP_021732668.1|2794070_2795252_+|class-I-SAM-dependent-rRNA-methyltransferase
MQRVQITGNSQRKVKDGYPLLVQDDLKDPSMKLTDGSFVALMASSQFMGYALIAKHRRQLGWVLSLDESETPTTDYFRKLFKQALVRRATSMDPQLPQRVFNADGDGLGGLAIDRYQDYYVFTWYAEGVYQQREMLYAAFEAATDHQFKGIYAKLRFNVEEANLKSQLVTGAAAPEPLLVTEGAVTYPLHLADDLTTGLLLDMRPIREWLAGAELQGKTVLNLFSQENGVTAAAAVAGAAKTISIETSKKGAKETADQLAVNNIDPDKQEIRAIEVNSYLDYAQKHRLSYDVVVVTAPTFARVKKQKFQVATDLTDLLTATLPVVRRDGQLVIATTANNFSMKKFKAAVTAAFVGSDRHFTLSETFRLPADFVTRKAYLASNYLKVLVLTLDK
>NZ_CP053337.1|WP_021732669.1|2792264_2793788_+|HAMP-domain-containing-histidine-kinase
MKLIYQQMLAFFAVIITVIVVLGFSFIRTTRTMLYQNSWQQLQQYAASIEKEAIRYNTKTNQVVGFNQQFLNDGTVILRDQHIHFSVYDANKTLVYPSGVGTSMDSTPGGSIYDPKISAKDWKKLKQNKIITQAPHVTFRSRNHNQPVNTPSLRTIDVLVPLFYKNGSTKKFVGAISIGSFEQTLQASEQQIEKNLFIALLVSGIAALLLSYILARYSVRRINRLRYATHSVANGDFDIQVDSNHKDEIDDLADDFNGMVNSLRASNEEIKRQEKRRREFMADAAHEMRTPLTTINGILEGLAYDAIPEEDKGHSIELMQNETKRLIRLVNENLDYEKIRTGQIALNKTNFDGAEVLHNLVEQLTKKAAAADDQFKLTVPEKLPVWADYDRFVQVLFNIMQNAIQFSQANVIEVTASRTDHATVVAIQDHGIGMTPDQVKNIWERYYKADPSRKNTKYGESGLGLAISHQLVQQHGGSIKVDSVENEGTCFTVTFPDEGFDKPIIDD
>NZ_CP053337.1|WP_021732655.1|2809990_2811967_+|hypothetical-protein
MKMFNKKRRDKNEDYRNHSERATATSTVAAQKPKPKATQSSTTPNVRSASGVRPTSSGVTASTSAPVKGQNRVNQRRATQTAAKNSAAIEREMADLNKQYQTLRGELKVQLVQDRKHEKQQYETLVAEQLNLEQQLKDAKITLSKQDKVVNTNDGERQGMVKTINASQKRYDDAKKALAKSDQTIKSLEKKITQSEQSLADLKQNEADMRKAIQGEQDLKKLFVLMKQQEKQAQDLYQKSDAINSELVKLQKREQTETRERSRKEHAITSAEKDLHTAQDALVAYDRKKKSAQDEQERSLNLINQKINRLQHDYDQNATIVKGLQQKVEGIDAKLKSDYGTTHLVSPVEFDQSAKYFLFSTDLIQSLSSEEKASMEMIMGLLKSEVKDNANVITVNYNDSLPDIWNNYQAAGLVDKRTGLYNMYYTIQAKVPGAVAKTKPELPDNPAWQYKRNADQQIVSIADDGGTPIMTLKYRKNGAIWYMTYFNGSLATRRDVYDAAGFLSVTQYLDRTNNSQVTLENFYRPDHSLAMVKQYGSNHELSIQLVNKEEAITNVFHSETQLLNWWLASVLQQQNSVLVMGINSPLFDQCLQATNESFHLLPIVSADDLDNQHVQDIISGKSKLSSLVVTDHDVQTAIEKQMTRDLEITVMPAAEVRA
>NZ_CP053337.1|WP_003642771.1|2812020_2812506_+|MarR-family-transcriptional-regulator
MMKTNTKKAKYDDAELFEKVLVGMSWLESHLREIIQTMVTDADVSFEQFLILYYLDHSTDHRITVKELAADRHVSSSAISRKLTYLINNDLIVLNIDPYDRRYRYLTLTAKGEKLARVIEKVNEERLGKFLDEFGRIRTSELTDELRMVSKVLVDTKEIKG
>NZ_CP053337.1|WP_021732654.1|2812554_2812827_-|hypothetical-protein
MRRYQPSPKSNGRVHHSISHNTNPYYGQRGADWVKNTNASLFNAQHERSQAKNHVERQVRHSMRQVLWVVVAIITMLLGGFILFSFAINI
>NZ_CP053337.1|WP_021732653.1|2812850_2813084_-|hypothetical-protein
MLLVYKDVFGIDHDDCHIVQTRHEFNRIFIIENEVGSRFTCIKDGAPLEKKMSGHWKYAKASDAPKNYAVPYKAQKN
>NZ_CP053337.1|WP_171284655.1|2813567_2814725_-|site-specific-integrase
MATIKKYQDKDGNTRYQFQVYLGVDPLTGKKKNTRRRGFKTKKEAQIVLSRLELDIYNHGLPTKNDNTIFKDIYQLWFTQYKQTVKESTWVTTQRLFRLHILPIFSDYRIAKISIKDCQKAINQWFNAGLVKYHTLMNYVAKVLDYAINIDLIGENPAKRVIVPVNKNDRSRKNLENYFDKAELQHFFECLNDDDNTPQANVFFRLAAFTGMRKSEMLCLEWSDIDFSNHTIRVNKTQSRGDGARLLVQAPKTARSNRTVYLDPTTIKILQHWQVDQKEWLLRFGFNINQGNHYVFANENNEMFQPSKPRKWLEHTLTKYDLKHVTVHAFRHTYATLAFEAHASIKSVQDQLGHSSYRTTLDIYTAVTAKQKNEATEKLANYLNF
>NZ_CP053337.1|WP_050480186.1|2814774_2815425_-|helix-turn-helix-transcriptional-regulator
MIRNRLAELLAERDLKISRVAAQLPNLSRNTITATASNTGKMIQLETVDTLCQFLHIEPTDFFEYLPFNIDFDITITKNDAFFTDVTRDTVHLRDEDIKFDIYIKVNNVSTQSKIFEYLGSNGNGFVGTDIPILLTRDENESTGFADFWHKKITPGFRSIVWDQLKNNLAQAISESLNERLAYEDVSFSLSPKNLILDTDFKSDLLNVDDFGELPF
>NZ_CP053337.1|WP_027822981.1|2815600_2815783_+|helix-turn-helix-domain-containing-protein
MKDDNKRYLTISQAMHYFNIKSRNTLKKNFIAKGLPIVIINGTKRIDQVDADKFMEAHKV
>NZ_CP053337.1|WP_027823047.1|2816051_2816282_+|hypothetical-protein
MTNSELIEQAKNLSVARDNLQMAIDYLDMVSASVNQGNVWAGRLFFADHRAGNVVENMQNVADSIMAVSNDICPED
>NZ_CP053337.1|WP_089197950.1|2816295_2817096_+|bifunctional-DNA-primase/polymerase
MNEFATLDKAIELAQKGYAVYPLIENTKKPPKGVAGYKDATNDQNTIFAWFKNSPYYNLGLRLDLSDLLVVDIDMHDPTKNGRTSLAQLFKQGFTLPSDTYIERTANGGLHYFLKYAGAKVRKIDVWPGVDLLSDFTVIAPSEINGKQYQPLDGRTLADIKPAPNWLVDELSTNNLNGAPEHAYATRQKKYTGRLLDEMVTGTAKGNRNAWLTKIAGRMFGVGASPKTVYNMLSVINDSFVDPALPSKEVNVIFQSILKRESKGVH
>NZ_CP053337.1|WP_171284656.1|2817095_2818490_+|virulence-protein
MGKAMDLPAETREAANNVIKMQRDADWQNDFKKNSDDGIKTQSLYNIRLIMEHDEMLKGLVVFDEFSEQIVKTPQADNSLFKKGFWNDSDDTLLRSYIEDHYNLLFSKENITDAVVTEARRKTINPVKARIEAVEWDGQPRAERYFIDYLGAEDNHYTRTITKKWLTGLIARAYVPGVKFEIVPILEGSQGLGKSTAGKNLYPDKFNDSLKGMGKQKDDYQQLQGSWIIEVAELSAMKKTDVEGIKNFISAQSDTYRNSYGRYALPHPRKCVFIGTTNQTDYLKDATGERRFYPIKCGVNKAKLDVWHPDENYILQVLAEATYWFRNGELLYLDQATVKEAKAYQMAAEAVDPMRDAIEEFLAMEVPTDWGKMSTSLKQSYVSDYGQQSKWLQDQVSNERKLLNQTTTREIMEVVFHKTVDRYLTGRTNSEAKRIKLLMDNMDGWKSQRIRMNGQRLHGYMREV

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP053337_1	1.1\|488361\|35\|NZ_CP053337\|CRISPRCasFinder	488361-488395	35	NC_004305	Lactobacillus phage phig1e, complete genome	34777-34811	5	0.857
NZ_CP053337_1	1.1\|488361\|35\|NZ_CP053337\|CRISPRCasFinder	488361-488395	35	X98106	Lactobacillus bacteriophage phig1e complete genomic DNA	34777-34811	5	0.857

1. spacer 1.1|488361|35|NZ_CP053337|CRISPRCasFinder matches to NC_004305 (Lactobacillus phage phig1e, complete genome) position: , mismatch: 5, identity: 0.857

cccgtcataccagcccttagcgcacatcaatttcc	CRISPR spacer
gacatcataccagcccttggcacacatcaatttcc	Protospacer
  *.**************.**.*************

2. spacer 1.1|488361|35|NZ_CP053337|CRISPRCasFinder matches to X98106 (Lactobacillus bacteriophage phig1e complete genomic DNA) position: , mismatch: 5, identity: 0.857

cccgtcataccagcccttagcgcacatcaatttcc	CRISPR spacer
gacatcataccagcccttggcacacatcaatttcc	Protospacer
  *.**************.**.*************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

902 : 50049

Lactobacillus_phage(46.43%)

lysis,transposase,portal,plate,protease,tail,capsid,tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_171284678.1\|902_2369_+\|portal	phage portal protein	X2CY64	Lactobacillus_phage	5.8e-140	56.1
WP_103127098.1\|2355_4026_+\|capsid	minor capsid protein	A9D9S7	Lactobacillus_prophage	1.5e-78	43.5
WP_056988255.1\|4012_4264_+	hypothetical protein	NA	NA	NA	NA
WP_056988256.1\|4411_4966_+	phage scaffolding protein	X2CYF9	Lactobacillus_phage	8.9e-49	56.8
WP_056988257.1\|4978_6019_+	hypothetical protein	Q20DD4	Lactobacillus_phage	2.4e-140	73.4
WP_056988258.1\|6032_6422_+	hypothetical protein	X2CXX4	Lactobacillus_phage	5.9e-23	42.6
WP_056988259.1\|6418_6814_+	hypothetical protein	A9D9T8	Lactobacillus_prophage	6.8e-35	63.3
WP_056988260.1\|6794_7193_+	HK97 gp10 family phage protein	A0A0A7RVN8	Clostridium_phage	8.1e-12	28.7
WP_056988261.1\|7202_7616_+	hypothetical protein	A9D9U4	Lactobacillus_prophage	6.9e-22	36.3
WP_056988262.1\|7608_7800_+	hypothetical protein	NA	NA	NA	NA
WP_171284585.1\|7800_9258_+\|tail	phage tail sheath subtilisin-like domain-containing protein	Q20DC8	Lactobacillus_phage	3.4e-100	46.2
WP_056944246.1\|9172_10093_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	7.1e-35	36.4
WP_056988264.1\|10227_10710_+\|tail	phage tail tube protein	Q20DC7	Lactobacillus_phage	3.0e-61	74.5
WP_056988265.1\|10723_11155_+	hypothetical protein	S6B9X5	Thermus_phage	4.5e-08	33.8
WP_056988266.1\|11386_15070_+	hypothetical protein	X2CYG3	Lactobacillus_phage	2.7e-08	35.9
WP_056988267.1\|15085_15778_+	hypothetical protein	L0P8M9	Lactobacillus_phage	1.1e-35	45.3
WP_056988268.1\|15781_16801_+	hypothetical protein	L0P6D8	Lactobacillus_phage	3.5e-59	41.2
WP_103127101.1\|16831_17107_+	DUF2577 domain-containing protein	A9D9W8	Lactobacillus_prophage	1.5e-12	35.2
WP_082618897.1\|17117_17549_+	DUF2634 domain-containing protein	A9D9X1	Lactobacillus_prophage	9.1e-25	51.3
WP_056988270.1\|17538_18687_+\|plate	baseplate J/gp47 family protein	L0P7C2	Lactobacillus_phage	8.1e-121	56.3
WP_056988271.1\|18679_19321_+	DUF2313 domain-containing protein	Q9AZ88	Lactobacillus_prophage	2.5e-26	42.1
WP_056988272.1\|19321_20155_+	hypothetical protein	NA	NA	NA	NA
WP_056988273.1\|20271_21099_+	hypothetical protein	NA	NA	NA	NA
WP_056988274.1\|21150_22110_+	hypothetical protein	A0A1B1IN44	Lactococcus_phage	6.5e-15	33.2
WP_146029293.1\|22111_22453_+	hypothetical protein	NA	NA	NA	NA
WP_120247159.1\|22452_22620_+	XkdX family protein	NA	NA	NA	NA
WP_056988276.1\|22711_23122_+	hypothetical protein	NA	NA	NA	NA
WP_056988277.1\|23135_23519_+	hypothetical protein	A0A2P0ZLF7	Lactobacillus_phage	2.1e-41	63.5
WP_056988279.1\|23729_24014_+\|lysis	lysis protein	A0A2P0ZLE8	Lactobacillus_phage	3.7e-19	54.3
WP_056988280.1\|24013_24922_+	SH3 domain-containing protein	A0A2P0ZLG2	Lactobacillus_phage	4.5e-98	76.9
WP_021732299.1\|25662_26874_+	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_021732298.1\|27352_29095_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_021732297.1\|29113_29905_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	7.0e-31	37.3
WP_080235726.1\|29885_31070_+	LCP family protein	NA	NA	NA	NA
WP_021732295.1\|31429_32371_-	glycosyltransferase family 2 protein	V9QJB1	Oenococcus_phage	3.1e-78	48.7
WP_021732294.1\|32847_33240_-	hypothetical protein	NA	NA	NA	NA
WP_021732293.1\|33404_33797_+	hypothetical protein	NA	NA	NA	NA
WP_021732292.1\|33832_35002_+	hydroxymethylglutaryl-CoA synthase	NA	NA	NA	NA
WP_021732291.1\|35048_35678_-	hypothetical protein	NA	NA	NA	NA
WP_021732290.1\|35777_36431_+	DNA alkylation repair protein	NA	NA	NA	NA
WP_003640747.1\|36530_37163_-	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	2.3e-16	56.2
WP_021732289.1\|37296_37554_+	DUF896 domain-containing protein	NA	NA	NA	NA
WP_080235722.1\|37651_37888_+	YneF family protein	NA	NA	NA	NA
WP_021730789.1\|37946_38585_-	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_021730790.1\|38697_39453_+\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
WP_021730791.1\|39439_39745_+	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_003640741.1\|39829_40828_+	D-2-hydroxyacid dehydrogenase	M1HKI4	Acanthocystis_turfacea_Chlorella_virus	2.3e-47	34.9
WP_021730792.1\|41067_41790_-	HAD family hydrolase	NA	NA	NA	NA
WP_021730793.1\|42013_42817_+	30S ribosomal protein S2	NA	NA	NA	NA
WP_021730794.1\|42919_43798_+	elongation factor Ts	NA	NA	NA	NA
WP_021730795.1\|43997_44720_+	UMP kinase	NA	NA	NA	NA
WP_021730796.1\|44721_45285_+	ribosome recycling factor	NA	NA	NA	NA
WP_021730797.1\|45404_46184_+	isoprenyl transferase	R9W0U9	Flavobacterium_phage	3.7e-24	43.8
WP_021730798.1\|46199_46985_+	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_021730799.1\|47022_48300_+\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_021730800.1\|48339_50049_+\|tRNA	proline--tRNA ligase	NA	NA	NA	NA

DBSCAN-SWA_2

581262 : 593081

Lactobacillus_phage(75.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021731391.1\|581262_582552_+	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	9.5e-102	49.6
WP_171284599.1\|582581_584864_+	HAD-IC family P-type ATPase	M1IAU8	Acanthocystis_turfacea_Chlorella_virus	3.3e-33	24.2
WP_021731388.1\|585273_587175_-	outer membrane protein	A0A2P0ZL91	Lactobacillus_phage	5.0e-59	76.6
WP_021731387.1\|587577_588018_+	nucleoside 2-deoxyribosyltransferase	A0A2P0ZL88	Lactobacillus_phage	6.3e-74	94.5
WP_021731386.1\|588086_588647_-	hypothetical protein	A0A2P0ZL75	Lactobacillus_phage	2.8e-95	93.0
WP_056988701.1\|588734_591173_-	flavocytochrome c	A0A2P0ZL82	Lactobacillus_phage	0.0e+00	96.7
WP_021731384.1\|591175_591790_-	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	1.3e-109	97.1
WP_021731383.1\|592133_593081_+	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	1.4e-171	95.9

DBSCAN-SWA_3

1184867 : 1193578

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021731227.1\|1184867_1185863_-	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	7.7e-51	37.9
WP_021731228.1\|1185996_1186782_-	oleoyl-[acyl-carrier protein] thioesterase	NA	NA	NA	NA
WP_021731229.1\|1186785_1187682_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	4.9e-81	55.3
WP_021731230.1\|1187781_1188129_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	5.4e-12	33.3
WP_021731231.1\|1188153_1189173_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	4.8e-32	33.2
WP_003640965.1\|1189189_1189519_-	cyclic-di-AMP receptor	NA	NA	NA	NA
WP_021731232.1\|1189515_1190181_-	dTMP kinase	M1PSC7	Streptococcus_phage	2.5e-53	52.2
WP_021731234.1\|1190669_1190921_-	YaaL family protein	NA	NA	NA	NA
WP_021731235.1\|1190935_1191535_-	recombination protein RecR	NA	NA	NA	NA
WP_003640956.1\|1191550_1191859_-	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
WP_021731236.1\|1191880_1193578_-	DNA polymerase III subunit gamma/tau	A0A1U9WR94	Streptococcus_virus	3.0e-55	37.0

DBSCAN-SWA_4

1327108 : 1433034

uncultured_Mediterranean_phage(15.38%)

bacteriocin,transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021731861.1\|1327108_1328407_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	2.2e-42	30.8
WP_003637671.1\|1328540_1328786_-	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_021731863.1\|1328912_1330205_-	transcription termination factor Rho	NA	NA	NA	NA
WP_003642050.1\|1330234_1331515_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_021731865.1\|1332972_1333167_-	hypothetical protein	NA	NA	NA	NA
WP_021731867.1\|1333998_1334727_-	PAS domain-containing protein	NA	NA	NA	NA
WP_021731868.1\|1334877_1335777_-	L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha	NA	NA	NA	NA
WP_021731869.1\|1335796_1336450_-	L-serine ammonia-lyase, iron-sulfur-dependent, subunit beta	NA	NA	NA	NA
WP_021731870.1\|1336801_1338082_-	serine transporter	NA	NA	NA	NA
WP_021731871.1\|1338433_1339705_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	2.9e-95	43.7
WP_021731872.1\|1340184_1341798_-	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	3.9e-145	49.4
WP_021731873.1\|1341971_1342580_-	DNA-directed RNA polymerase subunit delta	NA	NA	NA	NA
WP_021731874.1\|1342624_1343065_-	DUF1934 domain-containing protein	NA	NA	NA	NA
WP_021731876.1\|1343538_1344348_+	lipoate--protein ligase family protein	NA	NA	NA	NA
WP_171284682.1\|1344356_1345715_+	HD domain-containing protein	A0A1B1ISR1	uncultured_Mediterranean_phage	5.2e-26	32.9
WP_021731878.1\|1345735_1346545_+	sugar-phosphatase	NA	NA	NA	NA
WP_021731880.1\|1346927_1347914_-	hypothetical protein	NA	NA	NA	NA
WP_021731881.1\|1347996_1349019_-	YdcF family protein	NA	NA	NA	NA
WP_003643830.1\|1349308_1350289_-	ribose-phosphate diphosphokinase	A0A2K9L8D8	Tupanvirus	4.9e-42	36.3
WP_021731882.1\|1350678_1351503_-	serine hydrolase	NA	NA	NA	NA
WP_021731883.1\|1351672_1353055_-	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L140	Tupanvirus	3.7e-27	32.4
WP_021731884.1\|1353123_1353960_-	pur operon repressor	NA	NA	NA	NA
WP_033609531.1\|1354436_1355234_-	metal ABC transporter permease	NA	NA	NA	NA
WP_021731887.1\|1355226_1355925_-	ABC transporter ATP-binding protein	A0A1V0SGN0	Hokovirus	2.8e-15	26.5
WP_021731888.1\|1356217_1357162_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_021731889.1\|1357461_1358328_-	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase	NA	NA	NA	NA
WP_003642020.1\|1358459_1358711_-	Veg family protein	NA	NA	NA	NA
WP_033609513.1\|1358815_1359706_-	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	NA	NA	NA	NA
WP_033609514.1\|1359702_1360266_-	ribonuclease M5	NA	NA	NA	NA
WP_021731892.1\|1360252_1361029_-	TatD family hydrolase	NA	NA	NA	NA
WP_021731893.1\|1361171_1361912_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_021731894.1\|1362000_1362414_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_021731895.1\|1362482_1363664_-	multidrug effflux MFS transporter	NA	NA	NA	NA
WP_021731896.1\|1363899_1365951_-\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	1.8e-91	36.3
WP_021731897.1\|1366278_1367121_-	DUF72 domain-containing protein	NA	NA	NA	NA
WP_021731898.1\|1367120_1367825_-	NAD-dependent protein deacylase	NA	NA	NA	NA
WP_021731899.1\|1367846_1368806_-	hypothetical protein	NA	NA	NA	NA
WP_021731900.1\|1368798_1370073_-	hydroxymethylglutaryl-CoA reductase, degradative	NA	NA	NA	NA
WP_011101010.1\|1370100_1371018_-	Ppx/GppA family phosphatase	NA	NA	NA	NA
WP_021731901.1\|1371434_1372448_-\|tRNA	tRNA-dihydrouridine synthase family protein	NA	NA	NA	NA
WP_021731902.1\|1372560_1373307_-	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_021731903.1\|1373458_1374355_-	ROK family protein	NA	NA	NA	NA
WP_021731904.1\|1374475_1375912_-	6-phospho-beta-glucosidase	A0A0B5JD41	Pandoravirus	6.3e-30	25.5
WP_033609533.1\|1375929_1377285_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_003642000.1\|1377507_1377930_-	DUF3284 domain-containing protein	NA	NA	NA	NA
WP_003641999.1\|1377919_1378108_-	hypothetical protein	NA	NA	NA	NA
WP_021731906.1\|1378114_1379476_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_021731907.1\|1379548_1380259_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_021731908.1\|1380649_1381666_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_021731909.1\|1382103_1382880_-	carbon-nitrogen family hydrolase	NA	NA	NA	NA
WP_021731910.1\|1383138_1385448_+	ATP-binding domain-containing protein	NA	NA	NA	NA
WP_033609515.1\|1385540_1385744_-	hypothetical protein	NA	NA	NA	NA
WP_021731911.1\|1385899_1386586_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_033609516.1\|1386681_1387362_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_021731913.1\|1387449_1388118_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_021731914.1\|1388185_1388875_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_021731915.1\|1388965_1390342_-	HlyD family secretion protein	NA	NA	NA	NA
WP_021731916.1\|1390358_1392509_-	peptide cleavage/export ABC transporter	W8CYL7	Bacillus_phage	4.7e-45	27.9
WP_003641985.1\|1392774_1392945_+\|bacteriocin	two-peptide bacteriocin plantaricin EF subunit PlnE	NA	NA	NA	NA
WP_033609517.1\|1392969_1393128_+\|bacteriocin	two-peptide bacteriocin plantaricin EF subunit PlnF	NA	NA	NA	NA
WP_021731918.1\|1393221_1393995_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_021731919.1\|1394298_1395042_-	response regulator transcription factor	NA	NA	NA	NA
WP_021731920.1\|1395161_1395905_-	LytTR family transcriptional regulator DNA-binding domain-containing protein	NA	NA	NA	NA
WP_033609518.1\|1395905_1397234_-	GHKL domain-containing protein	NA	NA	NA	NA
WP_003641979.1\|1397424_1397571_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_021731922.1\|1398416_1398572_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_021731923.1\|1398595_1398754_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_021731924.1\|1400171_1400840_+	hypothetical protein	NA	NA	NA	NA
WP_021731925.1\|1402005_1403277_-	glycosyltransferase	A0A0P0YMN8	Yellowstone_lake_mimivirus	2.1e-05	27.1
WP_021731926.1\|1403361_1403523_-	hypothetical protein	NA	NA	NA	NA
WP_021731927.1\|1403563_1403848_-	hypothetical protein	NA	NA	NA	NA
WP_021731928.1\|1404368_1405553_-	cation:proton antiporter	NA	NA	NA	NA
WP_021731929.1\|1405597_1406974_-	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_021731930.1\|1407487_1408315_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_021731931.1\|1408474_1409347_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_021731932.1\|1409417_1410209_+	HAD family hydrolase	NA	NA	NA	NA
WP_021731933.1\|1410212_1411373_+	MFS transporter	NA	NA	NA	NA
WP_021731934.1\|1411376_1411994_+	sugar O-acetyltransferase	NA	NA	NA	NA
WP_021731935.1\|1412081_1412492_-	protein-export chaperone SecB	NA	NA	NA	NA
WP_021731936.1\|1412491_1413061_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003641945.1\|1413802_1414525_-	aquaporin family protein	M1HWZ0	Paramecium_bursaria_Chlorella_virus	3.2e-30	31.9
WP_021731938.1\|1414539_1416369_-	type 1 glycerol-3-phosphate oxidase	NA	NA	NA	NA
WP_021731939.1\|1416383_1417901_-	glycerol kinase GlpK	NA	NA	NA	NA
WP_021731940.1\|1418380_1419712_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_021731941.1\|1419790_1420762_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.1e-22	31.2
WP_056988338.1\|1420762_1422289_-	ABC transporter permease/substrate-binding protein	NA	NA	NA	NA
WP_021731943.1\|1422526_1422973_+	hypothetical protein	NA	NA	NA	NA
WP_021731944.1\|1423276_1424188_-	oxidoreductase	NA	NA	NA	NA
WP_021731945.1\|1424324_1425245_+	ribonucleoside hydrolase RihC	NA	NA	NA	NA
WP_021731946.1\|1425411_1425984_-	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit	NA	NA	NA	NA
WP_003646440.1\|1426561_1427032_-	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_021731948.1\|1427141_1428338_+	DUF2075 domain-containing protein	NA	NA	NA	NA
WP_003641932.1\|1428368_1428878_+	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_021731949.1\|1429007_1429376_-	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_021731950.1\|1429955_1431461_-	multicopper oxidase domain-containing protein	NA	NA	NA	NA
WP_021731951.1\|1431608_1432277_-	ribose 5-phosphate isomerase A	NA	NA	NA	NA
WP_021731952.1\|1432470_1433034_+\|protease	matrixin family metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_5

2813567 : 2872670

Lactobacillus_phage(37.21%)

integrase,holin,terminase,portal,protease,tail,capsid,head

attL 2813369:2813390|attR 2842577:2842592

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2813369:2813390	attL	NA	NA	NA	NA
WP_171284655.1\|2813567_2814725_-\|integrase	site-specific integrase	Q938N9	Temperate_phage	5.0e-54	34.8
2813369:2813390	attL	NA	NA	NA	NA
WP_050480186.1\|2814774_2815425_-	helix-turn-helix transcriptional regulator	A0A1W6JQE6	Staphylococcus_phage	4.7e-09	46.5
WP_027822981.1\|2815600_2815783_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_027823047.1\|2816051_2816282_+	hypothetical protein	NA	NA	NA	NA
WP_089197950.1\|2816295_2817096_+	bifunctional DNA primase/polymerase	NA	NA	NA	NA
WP_171284656.1\|2817095_2818490_+	virulence protein	Q4ZD27	Staphylococcus_phage	1.1e-68	36.0
WP_027822990.1\|2818636_2819056_+	hypothetical protein	NA	NA	NA	NA
WP_171284657.1\|2819079_2819391_+	hypothetical protein	NA	NA	NA	NA
WP_063489182.1\|2819377_2819719_+\|head	phage head closure protein	NA	NA	NA	NA
WP_171284658.1\|2819711_2820101_+	HNH endonuclease	A0A1J0MFT4	Staphylococcus_phage	2.1e-20	46.1
WP_021356979.1\|2820909_2821383_+\|terminase	phage terminase small subunit P27 family	NA	NA	NA	NA
WP_171284659.1\|2821379_2823083_+\|terminase	terminase large subunit	A0A2H4JBN3	uncultured_Caudovirales_phage	3.7e-122	40.7
WP_171284660.1\|2823237_2824338_+\|portal	phage portal protein	A0A2H4J9Q5	uncultured_Caudovirales_phage	2.1e-49	33.2
WP_171284661.1\|2824334_2825873_+\|capsid	phage major capsid protein	B8R651	Lactobacillus_phage	6.3e-44	25.4
WP_171284662.1\|2826069_2826339_+\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_171284663.1\|2826521_2826893_+	hypothetical protein	NA	NA	NA	NA
WP_171284664.1\|2826975_2827281_+	hypothetical protein	NA	NA	NA	NA
WP_021732652.1\|2827700_2827907_+	hypothetical protein	NA	NA	NA	NA
2827373:2827394	attR	NA	NA	NA	NA
WP_021732651.1\|2828256_2829378_-\|integrase	site-specific integrase	D6PSS4	Lactobacillus_phage	9.9e-47	32.7
2827373:2827394	attR	NA	NA	NA	NA
WP_021732650.1\|2829667_2830762_-	hypothetical protein	NA	NA	NA	NA
WP_003642778.1\|2830956_2831133_-	hypothetical protein	A0A2P0ZL93	Lactobacillus_phage	2.6e-10	51.7
WP_003642779.1\|2831407_2831689_-	hypothetical protein	NA	NA	NA	NA
WP_021732649.1\|2831910_2832630_-	hypothetical protein	NA	NA	NA	NA
WP_003642781.1\|2833235_2833604_-	hypothetical protein	NA	NA	NA	NA
WP_021732646.1\|2833947_2834883_-	hypothetical protein	NA	NA	NA	NA
WP_003644968.1\|2834905_2835319_-	ImmA/IrrE family metallo-endopeptidase	A0A0M4RD70	Bacillus_phage	3.4e-05	31.3
WP_011101082.1\|2835330_2835693_-	helix-turn-helix domain-containing protein	A0A0U4KKM4	Exiguobacterium_phage	2.6e-09	32.0
WP_011101083.1\|2835865_2836096_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003642787.1\|2836168_2836483_-	hypothetical protein	NA	NA	NA	NA
WP_021732645.1\|2836520_2837399_-	hypothetical protein	NA	NA	NA	NA
WP_033609666.1\|2837398_2837635_-	helix-turn-helix transcriptional regulator	A0A0K2CNE2	Brevibacillus_phage	7.4e-05	32.4
WP_033609665.1\|2837769_2837976_+	helix-turn-helix transcriptional regulator	A0A142F1D1	Bacillus_phage	8.5e-05	51.0
WP_003642791.1\|2837975_2838272_+	hypothetical protein	NA	NA	NA	NA
WP_003642792.1\|2838296_2838467_+	hypothetical protein	NA	NA	NA	NA
WP_003642793.1\|2838478_2838784_+	DUF771 domain-containing protein	NA	NA	NA	NA
WP_033609664.1\|2838851_2839364_+	helix-turn-helix transcriptional regulator	D6PST4	Lactobacillus_phage	8.0e-28	43.5
WP_021732643.1\|2839734_2840121_+	hypothetical protein	NA	NA	NA	NA
WP_021732642.1\|2840117_2841005_+	recombinase RecT	E9LUM3	Lactobacillus_phage	1.6e-60	47.0
WP_021732641.1\|2841036_2841789_+	PD-(D/E)XK nuclease-like domain-containing protein	A0A0P0IZH9	Lactobacillus_phage	7.0e-73	51.4
WP_021732640.1\|2841867_2842776_+	DnaD domain protein	NA	NA	NA	NA
WP_021732639.1\|2842772_2843060_+	hypothetical protein	NA	NA	NA	NA
WP_021732638.1\|2843056_2843590_+	hypothetical protein	O03915	Lactobacillus_phage	2.8e-39	54.3
WP_021732637.1\|2843582_2844002_+	RusA family crossover junction endodeoxyribonuclease	A8YQM5	Lactobacillus_phage	9.7e-24	42.3
WP_021732636.1\|2843998_2844229_+	hypothetical protein	O03916	Lactobacillus_phage	2.6e-23	63.2
WP_165570769.1\|2844308_2844470_+	hypothetical protein	NA	NA	NA	NA
WP_021732634.1\|2844500_2844680_+	hypothetical protein	K4HZV9	Lactobacillus_phage	1.9e-16	66.1
WP_003642805.1\|2844843_2845305_+	transcriptional regulator	D6PSV8	Lactobacillus_phage	1.1e-39	57.0
WP_021732633.1\|2846698_2846968_+	DUF2829 domain-containing protein	A0A0K2FLC4	Brevibacillus_phage	2.5e-12	45.5
WP_033609662.1\|2847009_2847537_+\|terminase	terminase small subunit	O03926	Lactobacillus_phage	5.0e-41	73.1
WP_003642809.1\|2847526_2848765_+\|terminase	PBSX family phage terminase large subunit	M1PG09	Streptococcus_phage	1.9e-139	61.3
WP_021732631.1\|2848776_2850285_+\|portal	phage portal protein	V5US18	Oenococcus_phage	5.3e-136	51.6
WP_033609661.1\|2850214_2850511_+\|protease	ribosomal-processing cysteine protease Prp	D2J003	Enterococcus_phage	1.1e-10	40.2
WP_003642814.1\|2850657_2852343_+\|capsid	minor capsid protein	V5US81	Oenococcus_phage	3.5e-120	58.5
WP_003642815.1\|2852317_2852596_+	hypothetical protein	NA	NA	NA	NA
WP_003642816.1\|2852647_2852854_+	hypothetical protein	NA	NA	NA	NA
WP_021732629.1\|2853026_2853704_+	DUF4355 domain-containing protein	Q6SE80	Lactobacillus_prophage	4.6e-15	32.1
WP_021732628.1\|2853718_2854069_+	hypothetical protein	V5UTH9	Oenococcus_phage	4.5e-30	63.8
WP_021732627.1\|2854088_2855111_+\|capsid	major capsid protein	V5US24	Oenococcus_phage	9.7e-118	62.8
WP_003642820.1\|2855123_2855300_+	hypothetical protein	NA	NA	NA	NA
WP_013355731.1\|2855311_2855644_+\|head,tail	phage head-tail connector protein	V9QJ97	Oenococcus_phage	1.8e-12	45.3
WP_003642822.1\|2855643_2855991_+	hypothetical protein	V5US85	Oenococcus_phage	3.2e-36	62.3
WP_021732626.1\|2855992_2856544_+	HK97 gp10 family phage protein	V5URV0	Oenococcus_phage	5.1e-65	62.8
WP_013355729.1\|2856543_2856909_+	hypothetical protein	V5UQS4	Oenococcus_phage	3.0e-29	53.4
WP_099447638.1\|2857010_2857394_+\|tail	phage tail protein	V5USQ9	Oenococcus_phage	1.8e-37	58.4
WP_003642826.1\|2857493_2857892_+	hypothetical protein	V9QJA0	Oenococcus_phage	3.0e-46	74.8
WP_031275283.1\|2857999_2858263_+	hypothetical protein	V9QKH3	Oenococcus_phage	2.3e-23	65.4
WP_021732625.1\|2858278_2864110_+\|tail	phage tail protein	V5URV5	Oenococcus_phage	8.6e-227	40.9
WP_099739626.1\|2864153_2864486_+	hypothetical protein	V5UQS8	Oenococcus_phage	2.2e-42	73.4
WP_021732623.1\|2869816_2870266_+	DUF1617 family protein	A0A2P0ZLE0	Lactobacillus_phage	7.5e-22	40.5
WP_021732622.1\|2870268_2870703_+	hypothetical protein	NA	NA	NA	NA
WP_114685360.1\|2870830_2872003_+	LysM peptidoglycan-binding domain-containing protein	E9LUR8	Lactobacillus_phage	7.1e-197	88.2
WP_021732620.1\|2872003_2872300_+	hypothetical protein	A0A1I9KK55	Lactobacillus_phage	9.9e-39	76.5
WP_024971558.1\|2872286_2872670_+\|holin	holin	A0A2H4PBB2	Lactobacillus_phage	4.4e-15	84.0

DBSCAN-SWA_6

3150606 : 3159867

Lactobacillus_phage(55.56%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_082618893.1\|3150606_3151011_-	helix-turn-helix transcriptional regulator	Q9T1J3	Lactobacillus_phage	3.5e-10	36.6
WP_056988234.1\|3151264_3151474_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_056988318.1\|3151489_3152218_+	ORF6C domain-containing protein	A0A1P8BM06	Lactococcus_phage	2.9e-47	43.3
WP_056988235.1\|3152238_3152499_+	hypothetical protein	NA	NA	NA	NA
WP_056988236.1\|3152669_3152927_+	hypothetical protein	NA	NA	NA	NA
WP_056988237.1\|3152913_3153114_+	hypothetical protein	NA	NA	NA	NA
WP_056988238.1\|3153463_3154222_+	ERF family protein	D7RWM8	Brochothrix_phage	3.7e-13	37.5
WP_056988239.1\|3154218_3154662_+	single-stranded DNA-binding protein	A0A1U9WQM3	Geobacillus_phage	1.8e-15	36.1
WP_056988241.1\|3155509_3156430_+	ATP-binding protein	A0A0P0I3L9	Lactobacillus_phage	1.2e-42	37.5
WP_171284672.1\|3156575_3156911_+	hypothetical protein	NA	NA	NA	NA
WP_171284673.1\|3156940_3157279_+	hypothetical protein	A0A0P0IXI3	Lactobacillus_phage	8.4e-18	48.2
WP_171284674.1\|3157265_3157727_+	hypothetical protein	NA	NA	NA	NA
WP_056988244.1\|3158014_3158467_+	pentapeptide repeat-containing protein	A8ASP3	Listeria_phage	1.9e-12	59.2
WP_082618895.1\|3158764_3159190_+	hypothetical protein	K4I239	Lactobacillus_phage	2.2e-63	79.3
WP_056988245.1\|3159543_3159867_+	DUF771 domain-containing protein	E9LUT3	Lactobacillus_phage	1.8e-25	50.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP053342

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

3593 : 15583

Enterococcus_phage(22.22%)

transposase,integrase

attL 5951:5965|attR 9984:9998

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_171284703.1\|3593_4769_-\|transposase	IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	1.8e-27	29.0
WP_021356783.1\|5128_6031_-	YitT family protein	M1Q1P6	Streptococcus_phage	1.1e-51	40.3
5951:5965	attL	NA	NA	NA	NA
WP_105450226.1\|6117_6750_-	recombinase family protein	A0A286S1P7	Klebsiella_phage	8.1e-14	33.2
WP_171284704.1\|6863_7676_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	Q716C2	Shigella_phage	2.7e-14	28.5
WP_105450228.1\|7804_8755_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	1.2e-98	54.6
WP_105450229.1\|8769_9696_-	ribonucleotide-diphosphate reductase subunit beta	A0A2H4P8A9	Corynebacterium_phage	2.2e-36	31.7
WP_082265534.1\|9802_11950_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	7.2e-256	60.5
9984:9998	attR	NA	NA	NA	NA
WP_071665479.1\|11977_12436_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	NA	NA	NA	NA
WP_057950377.1\|14435_14687_+\|transposase	IS3 family transposase	Q6J1X3	Lactobacillus_phage	2.1e-37	95.2
WP_171284705.1\|14740_15583_+\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	4.5e-153	97.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP053337

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP053342

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection