CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_AP023189	Pseudomonas sp. TUM18999	2 crisprs	csa3,DEDDh,DinG,cas3,WYL,PD-DExK	0	0	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_AP023189_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP023189_1

4514367-4514541

Orphan

Consensus_repeat	Method
TCGCGAATGAATTCGCTCCCAC	PILER-CR

2 spacers

The CRISPR arrays of NZ_AP023189_1

>merge|NZ_AP023189|1|4514367-4514541|PILER-CR
TCGCGAATGAATTCGCTCCCACCAAGGAGGGTTTGTGCCGGGTGGGATGCGGGTGTGCACCGGTGGCCTGGCTGGGCGAATGAATTCGCCCCTACGCGGGTTGTACCCGCCCTACCGGTTCGGCGTGAAACCCGGCACATCGGCGCCGGGATTTCGCGAATGAATTCGCTCCCAC

>NZ_AP023189|1|1|4514367-4514541|PILER-CR
TCGCGAATGAATTCGCTCCCAC	CAAGGAGGGTTTGTGCCGGGTGGGATGCGGGTGTGCACCGGTGGCCTGGCT
GGGCGAATGAATTCGCCCCTAC	GCGGGTTGTACCCGCCCTACCGGTTCGGCGTGAAACCCGGCACATCGGCGCCGGGATTTCGCGA
ATGAATTCGCTCCCAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP023189.1\|WP_173178904.1\|4500855_4502586_-\|bifunctional-isocitrate-dehydrogenase-kinase/phosphatase	unknown	unknown	gnl\|CDD\|235089
NZ_AP023189.1\|WP_173178889.1\|4521850_4522360_+\|phage-antirepressor	unknown	unknown	gnl\|CDD\|226144
NZ_AP023189.1\|WP_173178887.1\|4523269_4524175_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|184959
NZ_AP023189.1\|WP_173178905.1\|4499822_4500842_-\|AraC-family-transcriptional-regulator-ligand-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|378890
NZ_AP023189.1\|WP_173178895.1\|4514584_4515559_-\|cysteine-synthase-A	unknown	unknown	gnl\|CDD\|273465
NZ_AP023189.1\|WP_173178891.1\|4518377_4519556_+\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|226346
NZ_AP023189.1\|WP_173178888.1\|4522586_4523189_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP023189.1\|WP_173178896.1\|4512418_4514083_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|283599
NZ_AP023189.1\|WP_173178894.1\|4515689_4516769_+\|DUF748-domain-containing-protein	unknown	unknown	gnl\|CDD\|377502
NZ_AP023189.1\|WP_173178902.1\|4503721_4505464_+\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|224490
NZ_AP023189.1\|WP_175384276.1\|4524331_4524961_+\|hydrolase	unknown	unknown	gnl\|CDD\|238494
NZ_AP023189.1\|WP_173178900.1\|4506860_4507775_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NZ_AP023189.1\|WP_173178893.1\|4517054_4517900_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NZ_AP023189.1\|WP_173178903.1\|4502701_4503616_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NZ_AP023189.1\|WP_173178890.1\|4519657_4521523_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379114
NZ_AP023189.1\|WP_173178892.1\|4517956_4518352_+\|GFA-family-protein	unknown	unknown	gnl\|CDD\|226314
NZ_AP023189.1\|WP_173178898.1\|4509994_4510903_+\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|273359
NZ_AP023189.1\|WP_173178899.1\|4507882_4509625_+\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|224490
NZ_AP023189.1\|WP_173178897.1\|4511085_4512171_-\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270377
NZ_AP023189.1\|WP_173178901.1\|4505564_4506308_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273922

Protein	Function_ID	Function_description	E-value
NZ_AP023189.1\|WP_173178904.1\|4500855_4502586_-\|bifunctional-isocitrate-dehydrogenase-kinase/phosphatase	gnl\|CDD\|235089	PRK02946, aceK, bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated.	0
NZ_AP023189.1\|WP_173178889.1\|4521850_4522360_+\|phage-antirepressor	gnl\|CDD\|226144	COG3617, COG3617, Prophage antirepressor [Transcription].	2.12297e-20
NZ_AP023189.1\|WP_173178887.1\|4523269_4524175_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|184959	PRK14997, PRK14997, LysR family transcriptional regulator; Provisional.	1.02516e-120
NZ_AP023189.1\|WP_173178905.1\|4499822_4500842_-\|AraC-family-transcriptional-regulator-ligand-binding-domain-containing-protein	gnl\|CDD\|378890	pfam12625, Arabinose_bd, Arabinose-binding domain of AraC transcription regulator, N-term. AraC is a bacterial transcriptional regulatory protein with a DNA-binding domain at the C-terminus, HTH_AraC, pfam00165, and this dimerization domain which harbours the arabinose-binding pocket at the N-terminus. AraC positively and negatively regulates expression of the proteins required for the uptake and catabolism of the sugar L-arabinose 1,2,3].	4.21977e-41
NZ_AP023189.1\|WP_173178895.1\|4514584_4515559_-\|cysteine-synthase-A	gnl\|CDD\|273465	TIGR01139, Cysteine_synthase, cysteine synthase A. This model distinguishes cysteine synthase A (CysK) from cysteine synthase B (CysM). CysM differs in having a broader specificity that also allows the use of thiosulfate to produce cysteine thiosulfonate. [Amino acid biosynthesis, Serine family].	6.04818e-165
NZ_AP023189.1\|WP_173178891.1\|4518377_4519556_+\|VWA-domain-containing-protein	gnl\|CDD\|226346	COG3825, COG3825, Uncharacterized protein conserved in bacteria [Function unknown].	0
NZ_AP023189.1\|WP_173178896.1\|4512418_4514083_+\|MFS-transporter	gnl\|CDD\|283599	pfam05977, MFS_3, Transmembrane secretion effector. This is a family of transport proteins. Members of this family include a protein responsible for the secretion of the ferric chelator, enterobactin, and a protein involved in antibiotic resistance.	0
NZ_AP023189.1\|WP_173178894.1\|4515689_4516769_+\|DUF748-domain-containing-protein	gnl\|CDD\|377502	pfam05359, DUF748, Domain of Unknown Function (DUF748).	1.5387e-10
NZ_AP023189.1\|WP_173178902.1\|4503721_4505464_+\|amidohydrolase-family-protein	gnl\|CDD\|224490	COG1574, COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only].	9.72787e-156
NZ_AP023189.1\|WP_175384276.1\|4524331_4524961_+\|hydrolase	gnl\|CDD\|238494	cd01012, YcaC_related, YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them. Multimerisation interface seems not to be conserved in all members.	7.34392e-71
NZ_AP023189.1\|WP_173178900.1\|4506860_4507775_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	9.49093e-63
NZ_AP023189.1\|WP_173178893.1\|4517054_4517900_+\|AAA-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	6.21487e-52
NZ_AP023189.1\|WP_173178903.1\|4502701_4503616_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.81231e-62
NZ_AP023189.1\|WP_173178890.1\|4519657_4521523_+\|AAA-family-ATPase	gnl\|CDD\|379114	pfam13304, AAA_21, AAA domain, putative AbiEii toxin, Type IV TA system. Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.	1.36685e-15
NZ_AP023189.1\|WP_173178892.1\|4517956_4518352_+\|GFA-family-protein	gnl\|CDD\|226314	COG3791, COG3791, Uncharacterized conserved protein [Function unknown].	3.09181e-39
NZ_AP023189.1\|WP_173178898.1\|4509994_4510903_+\|EamA-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	3.60093e-17
NZ_AP023189.1\|WP_173178899.1\|4507882_4509625_+\|amidohydrolase-family-protein	gnl\|CDD\|224490	COG1574, COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only].	1.38462e-157
NZ_AP023189.1\|WP_173178897.1\|4511085_4512171_-\|extracellular-solute-binding-protein	gnl\|CDD\|270377	cd13659, PBP2_PotF, The periplasmic substrate-binding component of an ABC putrescine transport system and related proteins; contains the type 2 periplasmic-binding fold. This group represents the periplasmic substrate-binding domain that serves as the primary polyamine receptor of ABC-type putrescine-preferential transporter from gram-negative bacteria. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.0262e-176
NZ_AP023189.1\|WP_173178901.1\|4505564_4506308_+\|hypothetical-protein	gnl\|CDD\|273922	TIGR02001, gcw_chp, conserved hypothetical protein, proteobacterial. This model represents a conserved hypothetical protein about 240 residues in length found so far in Proteobacteria including Shewanella oneidensis, Ralstonia solanacearum, and Colwellia psychrerythraea, usually as part of a paralogous family. The function is unknown.	3.26584e-37

>NZ_AP023189.1|WP_173178896.1|4512418_4514083_+|MFS-transporter
MLQSVSPKNDLPRTPESEEPPKSGLFSPFTITAFRIIWIANLFANLGTWAQSVAAAWVVTEAHASPPTVAMIQVAAALPLVLLSIMSGVLADNHDRRKIMMAGLAFEMSGATFLTAMAFFGYLDPLLLIVSILWISIGGSITIPAWQAAVNEQVPAKMVGDAVLLNSVNYNVARAAGPAIGGLMLSAVGPAWVFLFNCLCYLGLIWAIWRWRRELPVRSLPPERLMEGVVAALRFTQYSSVTRLVMLRSFSFGISASAVWALLPLLAHRNPDGDAAVYGYMLGALGVGAILGSLGVNLARRGVGTSRLISFAGLLLGLVLLALGSLDSLWVIFPALVLGGACWIAAVASYNSAVQILVPDWVKARALALYQTALYGGLALGSFLWGHLAETMGVKGALFAAGCLMIACAFLLYQSRLPELDATSIAHAVTTLPGQPTFVFNPGRGSVLVTIEYRIPVERTRDFVRAMQILRRLRLRNGADRWALYRDTSDQENWQEILLVDNWLQHLRMLDRLTIADKAIIDNVTMLHEGEEPPRVRHGVSYESGSYEAKAAGS
>NZ_AP023189.1|WP_173178897.1|4511085_4512171_-|extracellular-solute-binding-protein
MRSSFAPLLLTLAVSGAAQAADTVKIYNWTDYIAPDTVATFSKETGIQATYDVYDSNETLDGKLMTGKSGYDIVVPSNHYMAKQIQAGALKKLDKSQLPNWKNLNPALLKALEVNDPGNEHGFPYLWGSTGIGYNPAKVKEVLGDNAPLDSWDLIFKPENMEKLAKCGVAILDNGPELLPITLNYLGLPHHSKKPEDYKTAEAALLKVRPFVRYFHSSKYVGDLANGEICVAVGFSGDILQAATRAKEAGNGVEIKYSTPKEGSPMWFDMIAMPVDAPDEKAGYAFMNYLLRPEVIAGVSNYVHYANGNNAAEPLVEAEIKADPAIYPPADVMAKLFALESMPLKIDRVRTRTWNTVKTGK
>NZ_AP023189.1|WP_173178898.1|4509994_4510903_+|EamA-family-transporter
MKPADLVRLLSLAAIWGASFLFMRVLVPVIGALPTAFFRVAISAIGLVAILALLRVTWDFRGKLGKILLIGVVSSGIPAAMYALAAEVLPAGYSAIFNATTPLMGVLIGGLFFGEKLTLPKAAGVLLGLAGVAVLTGAGPVAFDADLLRGALACLMATTCYGFAGFFTKRWINDAGGLDSGLSAFGAQAGATLCLLPIFLASSHAMPLAPLAEPGIWLALAGLGLLCTSFAYVIYFRLIANVGPVKTMTVTFLIPLFGVFWGALLLDESLSWAHLQGGVLIALALWLVLRPTVAAVGVERAS
>NZ_AP023189.1|WP_173178899.1|4507882_4509625_+|amidohydrolase-family-protein
MKRLALTLLATALICASMESMAAVDLILHNAKVYTAEPGQPLQQAVAVEDGKIRAVGSDADMLRLKEAGTRVVDLGGKVLMPGFVDSHSHAVMGGLELAAANIDTQLLPMDELERRLRQWRDDGKARQGDILSVGGLPSAYWSQVAEFERRFNQGEWKDVPIAFIGWDQHTGWVNQAMLKRAGIDADTVRALKGEQLATVGHHEDMRPNGFLADAGLDPVLAQYPTATPEQLLEAGRAALRYNLSLGITAWMDPAANAAPGEPLFDFKPTAQTLGILPVYKAMAEKGELTAHVAALLVAHPKSRPADLETLEQVRRQFQGVPNLSLPGIKIFADGVPEYPAQTAALLEPYKNSKKYGELLIDPSHFGELVSAADARGWLVHVHAIGDRAVRESLNGIEQARRDRHSGIPHSITHLQMVNPKEFARFKPLDVIASMQLYWASADDATLDLVQPYISAMAFQYQYPARSLLKNGATLAGASDWPVTTPQPWKAIYQAVSRKGPKGVLNPSEEIDRETMFQAYTLNAARTIGLDQQIGSLAPGKQADLILLDRDVFQVEPEALRDTRVLKTWFAGREVFEAAL
>NZ_AP023189.1|WP_173178900.1|4506860_4507775_-|LysR-family-transcriptional-regulator
MDKLSALSMFIATAEHGSFSRAAEHLGKTPSALTKAVGHLESELGVRLFERTTRRMALTEAGHIYLEGTRQALMQLQLAGEEVDQLQHELRGTLRLTAPPSFGPAFLNEVCCRYMDAHPQVRLEVDLNDAFVDLIDGGYDLALRDGPTDLPGLIARPLADNRVYLCCTPGYLERKGMGVTLENFQQHDWLIFQHPMLNRHFWWLRLGEERIRLAHPVAHLASDNYDFLLACLLRGHGLQPLPRWSAKPYLASGQLVRVMPEYLLEPDVFGPWVHVLYLSHRRRTRKVRAFIEMLEAYMQEQGIA
>NZ_AP023189.1|WP_173178901.1|4505564_4506308_+|hypothetical-protein
MKRSTTLLLAGLALAPLCSQAALPITDDFAVAVDLNLASDYRTRGISQTQGDPAIQAGATLLHASGLYAGAWNSNVDFGFGLKTRQEVDYYAGWFWQATDDVSLDLGVIKYAYPKESQFNQSEVYAILSAYGFKAAAYYSDDAPNIIGEDQDTLYTWVGYETQLPLEVGLELRYGRMDFKDPLFWSRNGTGSESYREWEAKLTRDFLGVTWGLAYVDTDLSESQCASNYGFTDTCSATVVASVSKSF
>NZ_AP023189.1|WP_173178902.1|4503721_4505464_+|amidohydrolase-family-protein
MKNFVPRLLAAAVAFASMEAMAGADMVLFNGKVFTADKARPMVQAIAVENGKVLAVGSDAEIKALADASTQRIDLGGKALMPGLIDTHSHAIFGGLEMSTANMGDEQVSLDELEKRLRTWRDDGTARHGDTLYVGGMTSAYWAQAEAMGQRFDQGEWAGVPIVFVGSDHHTAWANAAMRKRAGIDAKLVESLPEAERGTIGLGKDGAPNGFLVDAGWDRVAAVLPPMDPALLLRAGENAVRTNNSLGITAWMDPAANGAPGEPLFALKPTEKSVGVLPVYKALAEKGELTAHVAALLVAHPKSRPADLDTLEKVRQQFQGIDNLSLPGIKIFADGVLEYPAQSAALIDPYSNSHKQGELLIDPAHFGELVSAADARGWLVHIHAIGDRAVREALNGIEQARRDRQSGITHSITHLQLVNPKEFARFKPLDVIASMQLLWAAGDDYTLDMVKPYVSAFAFRYQYPAHSLLQQGATIAGASDWPVSSPNPWAAMAQAVTREGEKGVLNAEERLDRDTMFYAYTLNAARTIGQEQHIGSLAAGKQADFILLDRDVFTVDAKALAETQVLKTWFGGREVYTAAR
>NZ_AP023189.1|WP_173178903.1|4502701_4503616_-|LysR-family-transcriptional-regulator
MDKLGAIAMFVATAEQGSFSRAAEQLGKTPSALTKAVSHLEAELGARLFERSTRRIVLTEAGRLYLETARQLLQRLHDVGEEIGQLQHGLQGSLRMTAPLAFSRAFLDEVCAGFLAAYPQISLRVDLCDAFVDLVEAGYDLALREGQSDLPGLIARVVGRNRLALCASPAYLARKGVPTLADLDRHDWLAYRHPALSRQYWWVECDGQRTRLAQPAAPRLESDNYDLLLANALAGVGVLHTPLWSAAPYIADGRLVRLLADHEIDPDAFGDQILAVYPSHRRATGKVLAFIDYLAAFLEARGLA
>NZ_AP023189.1|WP_173178904.1|4500855_4502586_-|bifunctional-isocitrate-dehydrogenase-kinase/phosphatase
MAQQWPAADIARLILDGFDDYREHFRQITDGARARFEQAQWQEIQQAAAARIALYEEKVSEVGERLRAAFDEEVLLDVQLWPLVKSAYIKLIDLRFDDELSETWFNSIFCGLFSHDLISDGCMFIHTTRPSLRPHERAPQTRSYHPRGDLKAALLQILDDYRFAVPFDDLERDLDRLVAQLRDSLPDWVIKDPELCVELFSSTLYRNKGAYLVGRIYTRDEQWPLVIPLLHREGKGIQVDALITDEADVSIIFSFTRSYFMVDVPVPAEFVGFLKRILPGKHIAELYTSIGFYKHGKSEFYRALINHLANTDDRFIMAPGVRGMVMSVFTLPGFNTVFKIIKDRFSPSKNVDRNTVIEKYRLVKSVDRVGRMADTQEFADFRFPKAKFEPECLAELLEVAPSTVELEGDTVLIRHCWTERRMTPLNIYLESASEPQVREALDDYGLAIKQLAAANIFPGDMLLKNFGVTRHGRVVFYDYDEISYLTEVNFRFIPPPRYPEDEMSSEPWYSVAPHDVFPEEFPRFLFADIGQRKLFNQLHGDLYDADYWKSLQDAIRAGKVIDVFPYRRKERPDAIQ
>NZ_AP023189.1|WP_173178905.1|4499822_4500842_-|AraC-family-transcriptional-regulator-ligand-binding-domain-containing-protein
MGDPLFSRATWLNSLHMSTLTVACLGERGIDAASLLEGSGITEDDLRALQRLINPGQEQQVFANALRLADTPALGLELGQRTRISAYGLLGYALLSAPTLGEALRIGLGYPVLLGTYFHLRLVEEGDLAWLLASGYGEREALKPFNTELCLGSLRVICADLLGQPLPVAALELDYPEPPGAAPLYRQAFDRAPRFGRARSGLGFPRQWLERPLPLADPVTHREMLEQCRRQNAEFATRRAWLERVREQLAQRLASPPGLEELARAMNCSARSLRRHLAQQQTSYQQLLDDLRFARAKELLQQGELPIYRIAEELGFSETASLRHAFQRWSGQPPSQFRG
>NZ_AP023189.1|WP_173178895.1|4514584_4515559_-|cysteine-synthase-A
MTRIYADNSKAIGNTPLVMVNRLGPKGVTILAKVEGRNPAYSVKCRIGANMIWDAEEHGRLRPGMTLVEPTSGNTGIGLAFVAAARGYKLILTMPSSMSLERRKVLKALGAELVLTEPAKGMKGAIEKAAEIAAGNPEQYLLLQQFENPANPAIHEKTTGPEIWNDTDGAVDVLVAGVGTGGTITGVSRYIKQQCNKPILSVAVEPVTSPVISQTLAGEEVKPSPHKIQGIGAGFVPKNLDLSIVDRVEQITDDESKAMALRLMREEGILCGISGGAAMAVAVRLAEKPEMQGKTLVVILPDSGERYLSTMLFDGLFTEQELQQ
>NZ_AP023189.1|WP_173178894.1|4515689_4516769_+|DUF748-domain-containing-protein
MKRRYSLPLGALLTLVLLLVVAHFALPWLIRDYLNGKLADMGEYRGHIADVDLAWWRGAYRINGLSIVKADGAIPVPLLDAPGIDLAVSWHSLWYDHSVVARVIFEAPEVNFVDGGKNKQDSQTGAGTDWRDQLNKLLPITLDEVRVVNGRIAFHNFSSTPKVDIDASEVNASLYNLTNVADDSGERVARFEGRAQLLGHAPLEVEARFDPFKNFEDFELRLRARDVDLPRLNDFSRAYGKFDFKAGSGDLVIEARADNAQLSGYIKPLLRNVDVFDWEQDVENDDKGFLRSLWEVLVGGGETVLKNQQRDQFATRVELSGNVHRQDISAFQAFLSILRNAFIEAFTTRFERPPPEKND
>NZ_AP023189.1|WP_173178893.1|4517054_4517900_+|AAA-family-ATPase
MKFEGTQSYVATDDLKLAVNAAITLQRPLLVKGEPGTGKTMLAEQLAESFGARLITWHIKSTTKAHQGLYEYDAVSRLRDSQLNSEKVHDVRNYIKKGKLWEAFESEERVILLIDEIDKADIEFPNDLLQELDKMEFYVYETNETIKAKQRPIIIITSNNEKELPDAFLRRCFFHYIAFPDRETLQKIVDVHYPNIKKDLVAEALDVFFDVRKVPGLKKKPSTSELVDWLKLLMADNIGEAVLRERDPTKAIPPLAGALVKNEQDVQLLERLAFMSRRASR
>NZ_AP023189.1|WP_173178892.1|4517956_4518352_+|GFA-family-protein
MHNGSCLCGAVKYQVDAPIESATHCHCSQCRKGHGAAFATYGNVRWSSFRWTAGEDLVTRYHSSPGVTRSFCRQCGATLQWYSDKAHPNWVSIALGTLDSPLGEIPQKHIYPESKADWYAIADGLPREPRS
>NZ_AP023189.1|WP_173178891.1|4518377_4519556_+|VWA-domain-containing-protein
MLLNLFNEMRAAKVPVSVRELLDLINALKHNVVFADMDEFYFLSRTILVKDERHFDKFDRAFGAYFKGLENLNQHIEALIPEEWLRKEFERMLTDEERAQIQSLGGLDKLIEEFKKRLEEQKERHAGGNKWIGTGGTSPFGSGGFNPEGIRVGDAGKRQGKAAKVWDQREYKNLDDQVELGTRNIKVALRRLRKFARQGAQDELDLDGTIDHTARDAGLLNIQMRPERRNSVKLLLLLDIGGSMDAHVKVCEELFSACKTEFKHLEYFYFHNCVYESVWKNNLRRTSERTSTLDLLHKYGPDYKVVFVGDAAMAPYEITQAGGSVEHWNEEPGYVWIKRFMEKYKKLIWINPYPKDTWNYTASTNIMRELIEDQMYPLTLSGLEEGMKFLSK
>NZ_AP023189.1|WP_173178890.1|4519657_4521523_+|AAA-family-ATPase
MKGIRLEKIIIENFKKIERQTISVKPITAIVGGNASGKSSILQAAQLYTAICQASFKSVKRTGTVDVFKTLANEDIIYRPTATILDLRYKEPASQTKSFKLGFECTITTEDEKEKTSQLSVHISRGKNANLALDHEGDLSLMPGIGNQKKPFSILTPGLSGIPIKEEWRTKGALDAAAMHGDANLYLRTLLDHLFTQDLDENNIEKWNNESIDLDGLPEKSSWKLFSKLLDECYSGARLYITHNKNRDRYININVYYLDSYFTLDMASTGMLQVIQILAYACFYNPPLLLLDEPDAHLHADSQTRLHSALKALTDNTNTRILLATHSPQLIQLLQHDENASVVWLSEGKEVKVNPGQQPAIPILMELGALNLGAEAFYPRNKIILLTEDKDTRLVKLLAAANTKENIAAISYNGCNNLQGARQLALILRTLRPDAKIVIHRDRDFRTDSEIKFEKLIFDAWLKSEETDSIHEIFTHGNDIEHSFIDPRHLETALKKIANPEIIEKATTEALALSRDDIIGKIRSARAVIKERLYDSDRMKNKKSLRKGAGIPDIPPSDKHFLPKDGRTPLSIQQCHGKSAFRSLMSEIHKLVKGDSKAIEKAVTCNSPHLQNKDWTDALRL
>NZ_AP023189.1|WP_173178889.1|4521850_4522360_+|phage-antirepressor
MHDAYTPIVFQRHNLFLRTVMIDNQPWLVAIDFARLIGALRPNRMPRLVDPHQRRAVVLRHASGGSEEVIAISEAGAYRLLYRFAHPEHRCISRWLSEEVVPALYDRHRDAEATPRRAHMSWANQRIGILKWQGDIWIARQDLPVFLASRDDPALSDEPSWKRMPFTDW
>NZ_AP023189.1|WP_173178888.1|4522586_4523189_+|hypothetical-protein
MDTLRDGIDAYNQTYLEINGEEDELYTEGPASEEDIEQLAALTGPLPAELQGFYRTLGALKNQTESESHCFWIPAPAELADWLREQGGSAGIIDVIRAHWGGDRPEFDAGRHFGAEEIAALNERFIGYGWYRVADILEGAHFLFFDRDGRFGSLYYHQDDFASASQALKAMLRDGIPGEPLEQLLGNALEEVRASMEEFG
>NZ_AP023189.1|WP_173178887.1|4523269_4524175_-|LysR-family-transcriptional-regulator
MEDLNTLYYFTQVVEHGGFAPAGRALDMPKSKLSRRIAQLEERLGVRLIHRTSRHCSLTEIGQEYYQRCVAMRVEAEGAAEVIERNRCEPRGLVRIACPTTLLNSWVGPMLTRYMLKYPLVELFIESTNRRVDLLHEGFDIALRVRFPPLENTDMVIKVLADSTQCLVGRPDFLTRLPAGFAPEELGRLPSLHWGGAQRDYQWELFGPDGARLTIPHRPRMVTDDLLALRNGVLGGVGIAHLPRVAVREDLANGTLVEMLPGFSPKCGIVHAIFPSRRGLLPSVRSLIDFLGEEFAGSDMA
>NZ_AP023189.1|WP_175384276.1|4524331_4524961_+|hydrolase
MTHFTYNRLDKDNAVVLLVDHQAGLLSLVRDIEPDKFKNNVLALADLAKFFKLPTILTTSFETGPNGPLVPELKALFPDVPYIARPGQINAWDNEDFVKAIKATGKKQLIIAGVVTEVCVAFPALSALEEGFEVFVVTDASGTFNEITRDAAWNRMSQAGAQLMNWFGVACELHRDWRNDVEGLAALCSNHIPDYRNLMTSYAALTGNK

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Crispr_ID: NZ_AP023189_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP023189_2

5123833-5123940

Orphan

Consensus_repeat	Method
GTGGGGTGCAGCTCCTGCGGGGGT	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_AP023189_2

>merge|NZ_AP023189|2|5123833-5123940|CRISPRCasFinder
TCTGGGTGCAGCTGCTGCGGGGGTGGGGTGCAGTATCTGCGGGGGTGGGGTGCAGCTCCTGCGGGGGTAGACCCGCACCATATGCGGGGGTGCATTTGCTGCGGGGGT

>NZ_AP023189|2|1|5123833-5123940|CRISPRCasFinder
TCTGGGTGCAGCTGCTGCGGGGGT	GGGGTGCAGTATCTGCGGGG
GTGGGGTGCAGCTCCTGCGGGGGT	AGACCCGCACCATATG
CGGGGGTGCATTTGCTGCGGGGGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP023189.1\|WP_173176277.1\|5122352_5122568_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP023189.1\|WP_173176246.1\|5125942_5126821_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP023189.1\|WP_173176244.1\|5127086_5127470_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP023189.1\|WP_173176257.1\|5121279_5121708_-\|VRR-NUC-domain-containing-protein	unknown	unknown	gnl\|CDD\|370112
NZ_AP023189.1\|WP_173176263.1\|5119319_5119553_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP023189.1\|WP_111261794.1\|5120366_5120942_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP023189.1\|WP_173176261.1\|5119555_5119849_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP023189.1\|WP_173176250.1\|5124213_5124828_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP023189.1\|WP_173176275.1\|5125216_5125900_+\|repressor-protein-c2	unknown	unknown	gnl\|CDD\|224885
NZ_AP023189.1\|WP_173176234.1\|5129519_5129765_+\|DUF1654-domain-containing-protein	unknown	unknown	gnl\|CDD\|311699
NZ_AP023189.1\|WP_173176254.1\|5121697_5122000_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP023189.1\|WP_173176248.1\|5124894_5125131_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374243
NZ_AP023189.1\|WP_173176238.1\|5128501_5128741_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP023189.1\|WP_111261792.1\|5122572_5123352_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP023189.1\|WP_173176236.1\|5128878_5129412_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP023189.1\|WP_173176240.1\|5127833_5128505_+\|SOS-response-associated-peptidase-family-protein	unknown	unknown	gnl\|CDD\|376837
NZ_AP023189.1\|WP_173176279.1\|5121996_5122353_-\|recombinase	unknown	unknown	gnl\|CDD\|374800
NZ_AP023189.1\|WP_173176259.1\|5120953_5121250_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP023189.1\|WP_021217129.1\|5119851_5120160_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP023189.1\|WP_173176242.1\|5127511_5127703_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_AP023189.1\|WP_173176248.1\|5124894_5125131_-\|hypothetical-protein	gnl\|CDD\|374243	pfam15943, YdaS_antitoxin, Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT. YdaS_antitoxin is a family of putative bacterial antitoxins, neutralising the toxin YdaT, family pfam06254.	0.000868564
NZ_AP023189.1\|WP_173176257.1\|5121279_5121708_-\|VRR-NUC-domain-containing-protein	gnl\|CDD\|370112	pfam08774, VRR_NUC, VRR-NUC domain.	5.31638e-09
NZ_AP023189.1\|WP_173176240.1\|5127833_5128505_+\|SOS-response-associated-peptidase-family-protein	gnl\|CDD\|376837	pfam02586, SRAP, SOS response associated peptidase (SRAP). The SRAP family functions as a DNA-associated autoproteolytic switch that recruits diverse repair enzymes onto DNA damage. We propose that the human protein Q96FZ2:UniProtKB, the eukaryotic member of the SRAP family, which has been recently shown to bind specifically to DNA with 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxycytosine, is a sensor for these oxidized bases generated by the TET (tetrahedral aminopeptidase of the M42 family) enzymes from methylcytosine. Hence, its autoproteolytic activity might help it act as a switch that recruits DNA repair enzymes to remove these oxidized methylcytosine species as part of the DNA demethylation pathway downstream of the TET enzymes.	1.36966e-65
NZ_AP023189.1\|WP_173176279.1\|5121996_5122353_-\|recombinase	gnl\|CDD\|374800	pfam16786, RecA_dep_nuc, Recombination enhancement, RecA-dependent nuclease. REF is a family of P1-like phage RecA-dependent nucleases. It does not appear to act as a positive RecA regulator. It is a new kind of enzyme, a RecA-dependent nuclease.	1.48973e-18
NZ_AP023189.1\|WP_173176275.1\|5125216_5125900_+\|repressor-protein-c2	gnl\|CDD\|224885	COG1974, LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms].	1.49849e-32
NZ_AP023189.1\|WP_173176234.1\|5129519_5129765_+\|DUF1654-domain-containing-protein	gnl\|CDD\|311699	pfam07867, DUF1654, Protein of unknown function (DUF1654). This family consists of proteins from the Pseudomonadaceae.	5.91066e-16

>NZ_AP023189.1|WP_111261792.1|5122572_5123352_-|hypothetical-protein
MLTPDQEDQLLVSLFATAEAMGQELTQAAGLMMIDDLKGYPEPVVVAALQACRRELTGKLTIGAILQRVQAADGRPGRDEAWSIALAASDEFESVMLTEEILAALQVAKPSLDMRDKVGARMSFLSAYDRLVETARREGKPVKWSLSIGYDLQRRALAVEQAVLLQRLPAPVGQQLLADLREQGVPVSQDGAAIAGLLTGRTGNPSPQLRERLLELKKSLAEQKGARARARREELNQYDERLKARHAARMAEAQGADHG
>NZ_AP023189.1|WP_173176277.1|5122352_5122568_-|hypothetical-protein
MRWRQKRDRDHKLINDCWVTECGYTIAICRLPNNRYTITAPGGSAPFAYTNERDDITPLILAHKEAQAVPA
>NZ_AP023189.1|WP_173176279.1|5121996_5122353_-|recombinase
MQGRAVTAEQKRWHDKLVSEVGCIACRADGRLGNTHCSIHHIGGRTKRGAHWNVIPLCGPHHQTGGEGVALHHNKARFVARYGREDDLLAECAKILATEGHDIPAGFLAWLDGDEVMA
>NZ_AP023189.1|WP_173176254.1|5121697_5122000_-|hypothetical-protein
MRRGRGISPLTHKRHPDGYTVNLKMHDPELVAMGWVRVEQYRHEKGGHAVIAEFGTQDGFPCWMYRTRMADGRSFGVFPTAIGAAKWIERELAREVAHVG
>NZ_AP023189.1|WP_173176257.1|5121279_5121708_-|VRR-NUC-domain-containing-protein
MSGKRLVSTHAFRRPSVDYEGKEQASLFKWLALQHPQAFKLAYHVPNGGHRVKAVAAKLKGQGVKAGVSDIVLPMARGGYFGLYIEFKATPPHDSPVTESQQSYLMSVELQGYMALVCRGINEAIEVINGYMAMPPTQAVKG
>NZ_AP023189.1|WP_173176259.1|5120953_5121250_-|hypothetical-protein
MEVIDLAACPDCAGQGWTKGLFHDLQCNTCGASGMVSKETGEALPAEVLVLQLRLRLNQRDRRLAQLEGTQQSKGGPHDDYRGKRNPAGIGGGNWTGD
>NZ_AP023189.1|WP_111261794.1|5120366_5120942_-|hypothetical-protein
MVYASVLAAVVSALAAETIDNTAKQAWQKLYRPGHEDGHDFATLMGTDGAGLNRTDVDCWVFARLHSQLKPRHWDVLAARYGTHKGRKVAAIGRLCPLIPSHAPKLFVQKAVTAWAIPQMKGVDGKRSCDMIVLPKSFYDMNTWDLDARPEQTRRRWRGDVRKRLDEMVEEALIAAGEILEAEGVLFTEAA
>NZ_AP023189.1|WP_021217129.1|5119851_5120160_-|hypothetical-protein
MEPTSTAAGAVFAKYGVAIAGFAGAVLSLSFLKGLTRKEAGLAVLTGFGSAVFTTHFVINYFGLPADADSRNGVAFLIGLLAMNIIPAIKAAAERFTPTRGT
>NZ_AP023189.1|WP_173176261.1|5119555_5119849_-|hypothetical-protein
MINSLLIGLAALLCILVVLAALDYLRAVSVYEHPVLCLSFYLVAIGAFGGLVVTIKTWHFDPYSALVHSGLLLFAFVKRRHIFRDEWGWTGAERRRS
>NZ_AP023189.1|WP_173176263.1|5119319_5119553_-|hypothetical-protein
MLGYMTAQEAKRLGFTHHGKYYGIPVWVGDPHGNCMVATKWAPLELLMSLWHHVEGLCHAMRGTEPTFMFLVGREIE
>NZ_AP023189.1|WP_173176250.1|5124213_5124828_-|hypothetical-protein
MTLSNERHGCSRDQVLVAHANEMITRTGFKSPKFAHRLNRLVVEALGAQAQDRKVPDLESIAGGDGAEFLKQADTWLKRVQRWLDGSVDFPSWLEEPWVDALEPEYRERCTNELAARHGLVAVRQQSGDACPVMAFGQLVGHLGSTVEACGVVLADGKIDALDHQHLPQMVESLLAAESRCAELRRVAENVIADLRQANLKVVS
>NZ_AP023189.1|WP_173176248.1|5124894_5125131_-|hypothetical-protein
MSELKNAINKAGGPAAAAKACGKSARAIYKWLAAGALPRTDFSGETDYAGCLAAAAAARGEPFEREWLLKNAKPAKAA
>NZ_AP023189.1|WP_173176275.1|5125216_5125900_+|repressor-protein-c2
MVQTEDLRAGFAERLKKAMADKGLPEWGAGARLAKITGVTPKATSKWLNGEAVPGPANLLAIAEELCVRREWLEYGEGLPQAIDNAELVPQPSRYYRFPVVSSVVAGGWGDAIQAYEPGAEDRFEKTDTKVKGPAFWLEVEGDSMTSLSGPSIPEGMLILVDTGIEPQPGHLVVAKLDTEEKATFKKLVQDGGKLYLKPLNTGYNPIEINGNCRIIGVVREAKMKLL
>NZ_AP023189.1|WP_173176246.1|5125942_5126821_+|hypothetical-protein
MEVQKQPDIQETVFTISYDAKGDLASHTIDARDLGMAIIGMNDLITKAADIVSNGSSEADLKVVAPAKEGSLEIVFALLADPVTTVAVLKSIGIGAGAIVAGAASAIGIMDRVKDKKIDRVIIDKATNTATVYVGDEQIQTSDKVAQLVASREIRQALHNVIQAPLAGREDASIKFEAEGVTVKLDDQEIRNFTPIRADIVDKEEKREFQKVVQFTKINFRGRRGWQVLSNDGQEYGVTIRDADFLNKISSNEEQFQKDKSYTVQIEQTDITTVSGTSTRYAIVRVINEFNP
>NZ_AP023189.1|WP_173176244.1|5127086_5127470_+|hypothetical-protein
MKNNMFMALATSSLNALAVVIGTFIESPKASQALLAAVSLLSPFLAIYLLRFYIKIAHPAELIRQISALEASIAICKSHLKDKNASDEFKQKTRRQMEKFQTQLQNIRSTFEAGRTHVTTSIDSNSE
>NZ_AP023189.1|WP_173176242.1|5127511_5127703_-|hypothetical-protein
MRLSLSAAAAWKEVHDFMAKDPDMGDVKNQDLLFRLQSAADQAAWAYWENVDEEDANAEPDEV
>NZ_AP023189.1|WP_173176240.1|5127833_5128505_+|SOS-response-associated-peptidase-family-protein
MCGRVAQFMSWAEIYHLLNIHNLPPGAPLEPRYNVAPTTQVQVVLPLEDDARVAPARWGWRPHWAQDRAAPINARAEKVAHGPFFRSIWPNRMLCPVSGWFEWVDEGEKRKQPYFIRRRDGTPTLCASIGQVHDEPQDSDGFVIITADALGGMVDVHDRRPVAFSPALAREWLDPATPRERAEEMLAAGEGPDVFEWYRVDRAVGNVRNQGPQLVDPLPAQLI
>NZ_AP023189.1|WP_173176238.1|5128501_5128741_-|hypothetical-protein
MIRNLAELHPDERAAMEHEKAQSYLFWQQNLERAKGEAAKIRGEKDRKKGKWAEWARAEIAALQPDQYRSMVEREVNRP
>NZ_AP023189.1|WP_173176236.1|5128878_5129412_+|hypothetical-protein
MNKRHLEERRRFLLDQWNGALDDDHTFRYSPDAHYQALLEIIDEFYHSGVIGLGHRQELVTRALGAYSFHVEEGIAADVYFNPNFYYELLDGDQLLGTVLEGYITGLTYNRLGVIWHDWVDGAWHYQMKDADLNVVGRVEKLQVIRPGLAPLTLRCVVPPKYEFRDWRETVLAPERD
>NZ_AP023189.1|WP_173176234.1|5129519_5129765_+|DUF1654-domain-containing-protein
MAEEALQRPEQSSYYHLTRRVQLLLSTPRAQVEHQAVIYREPSDSSSDWDRLLEEIRDTEGVALTHRPDGSIHVAWFSNHC

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

633772 : 702115

Vibrio_phage(25.0%)

holin,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_173174970.1\|633772_634258_-\|transposase	transposase	NA	NA	NA	NA
WP_173174968.1\|634451_636629_-	TIGR01666 family membrane protein	NA	NA	NA	NA
WP_173174966.1\|636784_637963_-	aminoacetone oxidase family FAD-binding enzyme	NA	NA	NA	NA
WP_173174964.1\|638116_638851_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_173174962.1\|638847_640086_-	diguanylate cyclase	NA	NA	NA	NA
WP_173174953.1\|640156_641539_-	ATP-dependent RNA helicase DbpA	E3T5E1	Cafeteria_roenbergensis_virus	2.1e-46	31.8
WP_173174951.1\|641622_643038_-	multidrug transporter subunit MdtD	NA	NA	NA	NA
WP_173174949.1\|643165_644197_+	TMAO reductase system periplasmic protein TorT	NA	NA	NA	NA
WP_173174947.1\|644254_645946_-\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	5.3e-52	30.4
WP_173174938.1\|646023_647496_-	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_173175261.1\|647858_649394_+	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	8.3e-20	27.4
WP_173174936.1\|649509_650112_-	transcriptional regulator BetI	NA	NA	NA	NA
WP_173174934.1\|650316_651174_-	glycine betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_111259628.1\|651306_652251_-\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_021218174.1\|652302_653187_-	proline/glycine betaine ABC transporter permease	NA	NA	NA	NA
WP_111259626.1\|653189_654386_-	glycine betaine/L-proline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.4e-30	38.7
WP_173174932.1\|655058_655997_-\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_173174929.1\|656266_657643_+	L-serine ammonia-lyase	NA	NA	NA	NA
WP_111259623.1\|658058_659159_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_111259622.1\|659456_659702_-	hypothetical protein	NA	NA	NA	NA
WP_173174927.1\|659733_660513_-	electron transfer flavoprotein subunit beta	NA	NA	NA	NA
WP_173174925.1\|660502_661735_-	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
WP_173174923.1\|661781_663746_-	dimethylglycine demethylation protein DgcB	NA	NA	NA	NA
WP_173174921.1\|663857_665918_-	dimethylglycine demethylation protein DgcA	NA	NA	NA	NA
WP_111259617.1\|665934_666465_-	hydrocarbon binding protein	NA	NA	NA	NA
WP_111259616.1\|666674_667652_-	membrane dipeptidase	NA	NA	NA	NA
WP_173174919.1\|667870_668881_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_173174917.1\|669121_670060_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_173174915.1\|670151_671039_+	3-keto-5-aminohexanoate cleavage protein	NA	NA	NA	NA
WP_173174913.1\|671103_672069_+	L-carnitine dehydrogenase	NA	NA	NA	NA
WP_173174911.1\|672143_672623_+	thioesterase family protein	NA	NA	NA	NA
WP_173174909.1\|672638_673265_-	response regulator	NA	NA	NA	NA
WP_173174907.1\|673795_677380_+	transporter substrate-binding domain-containing protein	A0A1V0SGX0	Hokovirus	3.2e-38	34.6
WP_173174904.1\|677393_678602_-	EAL domain-containing protein	NA	NA	NA	NA
WP_173174902.1\|678769_679405_+	response regulator	NA	NA	NA	NA
WP_173174900.1\|679707_680442_+	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_173174898.1\|680519_683162_+	fimbria/pilus outer membrane usher protein	NA	NA	NA	NA
WP_173174896.1\|683516_683825_-	hypothetical protein	NA	NA	NA	NA
WP_173174894.1\|684357_684735_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_173174892.1\|684986_686276_-	glycine-betaine demethylase subunit GbcA	NA	NA	NA	NA
WP_173174890.1\|686623_687727_+	glycine-betaine demethylase subunit GbcB	NA	NA	NA	NA
WP_173174888.1\|688535_689579_-	low specificity L-threonine aldolase	NA	NA	NA	NA
WP_173174886.1\|689812_690112_+	hypothetical protein	NA	NA	NA	NA
WP_173174884.1\|690281_690587_-	NIPSNAP family protein	NA	NA	NA	NA
WP_175384236.1\|691090_692344_+	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	1.4e-102	53.8
WP_173177467.1\|692359_693610_+	sarcosine oxidase subunit beta family protein	NA	NA	NA	NA
WP_173177469.1\|693621_693948_+	sarcosine oxidase subunit delta family protein	NA	NA	NA	NA
WP_173177471.1\|693944_696965_+	sarcosine oxidase subunit alpha family protein	NA	NA	NA	NA
WP_173177473.1\|697022_697664_+	sarcosine oxidase subunit gamma family protein	NA	NA	NA	NA
WP_173177475.1\|697773_698631_+	formyltetrahydrofolate deformylase	NA	NA	NA	NA
WP_173177477.1\|698808_700008_+	formaldehyde dehydrogenase, glutathione-independent	A0A2K9L7I1	Tupanvirus	6.5e-12	28.9
WP_173177661.1\|700156_702115_-\|holin	choline BCCT transporter BetT	A0A2I7QNT1	Vibrio_phage	1.1e-19	27.3

DBSCAN-SWA_2

1110397 : 1170674

uncultured_virus(14.29%)

integrase,transposase,coat

attL 1103987:1104002|attR 1128150:1128165

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1103987:1104002	attL	NA	NA	NA	NA
WP_175384242.1\|1110397_1111924_+\|transposase	IS66 family transposase	A0A218MNE7	uncultured_virus	1.7e-121	46.8
WP_170050745.1\|1111925_1112912_-	hypothetical protein	NA	NA	NA	NA
WP_021219117.1\|1113322_1114015_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_021219116.1\|1114227_1115454_+	sterol desaturase family protein	NA	NA	NA	NA
WP_021219115.1\|1115450_1116023_+	hypothetical protein	NA	NA	NA	NA
WP_003090707.1\|1116104_1116812_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_173180457.1\|1117138_1118361_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	1.1e-115	75.1
WP_173180334.1\|1118486_1121003_+	ATP-dependent helicase HrpB	A0A2H4UU36	Bodo_saltans_virus	2.9e-30	25.3
WP_173180335.1\|1121128_1121950_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_173180333.1\|1122594_1123203_-	hypothetical protein	NA	NA	NA	NA
WP_173180332.1\|1123203_1125300_-\|integrase	integrase	NA	NA	NA	NA
WP_173180331.1\|1125289_1127251_-	hypothetical protein	NA	NA	NA	NA
WP_111261477.1\|1129822_1130263_-	hypothetical protein	NA	NA	NA	NA
1128150:1128165	attR	NA	NA	NA	NA
WP_173180330.1\|1130638_1131721_-	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_173180329.1\|1131973_1132777_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_173180328.1\|1132770_1133202_-	VOC family protein	NA	NA	NA	NA
WP_173180327.1\|1133248_1133911_-	hypothetical protein	NA	NA	NA	NA
WP_173180326.1\|1133993_1134566_-	isochorismatase family protein	NA	NA	NA	NA
WP_111261471.1\|1134786_1135260_+	NYN domain-containing protein	NA	NA	NA	NA
WP_173180325.1\|1135294_1135897_+	3'-5' exonuclease	A0A0A7RWA3	Clostridium_phage	8.0e-19	35.4
WP_111261469.1\|1136655_1137129_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_173173583.1\|1137288_1138194_+	drug/metabolite exporter YedA	NA	NA	NA	NA
WP_173173580.1\|1138283_1139609_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.1e-55	33.9
WP_173173609.1\|1139817_1140648_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_173173578.1\|1141309_1142428_+	polyamine ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.9e-30	37.2
WP_173173576.1\|1142514_1143654_+	extracellular solute-binding protein	NA	NA	NA	NA
WP_173173574.1\|1143763_1144675_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_173173572.1\|1144676_1145489_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_173173570.1\|1145507_1146977_+	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_173173567.1\|1147281_1147749_-	PAS domain-containing protein	NA	NA	NA	NA
WP_173173565.1\|1147752_1148760_-	response regulator	NA	NA	NA	NA
WP_173173563.1\|1148847_1149213_-	VOC family protein	NA	NA	NA	NA
WP_173173561.1\|1149497_1150100_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_173173559.1\|1150221_1151598_-	amidohydrolase family protein	NA	NA	NA	NA
WP_173173557.1\|1151619_1152960_-	purine/pyrimidine permease	NA	NA	NA	NA
WP_173173555.1\|1153063_1154116_-	GTP-binding protein	NA	NA	NA	NA
WP_173173553.1\|1154112_1154733_-	UbiX family flavin prenyltransferase	NA	NA	NA	NA
WP_173173551.1\|1154729_1156127_-	UbiD family decarboxylase	NA	NA	NA	NA
WP_043245036.1\|1156245_1157151_-	amidohydrolase	NA	NA	NA	NA
WP_021217540.1\|1157155_1158085_-	amidohydrolase	NA	NA	NA	NA
WP_173173549.1\|1158579_1159479_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_173173547.1\|1159602_1160070_+	2Fe-2S iron-sulfur cluster binding domain-containing protein	NA	NA	NA	NA
WP_173173545.1\|1160066_1162277_+	molybdopterin-dependent oxidoreductase	NA	NA	NA	NA
WP_043245042.1\|1162309_1163221_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_173173543.1\|1163222_1164455_-	TIGR03862 family flavoprotein	NA	NA	NA	NA
WP_173173541.1\|1165274_1166195_-	histone deacetylase	A0A1V0SJS0	Klosneuvirus	8.5e-12	32.8
WP_173173539.1\|1166288_1166846_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_173173537.1\|1167092_1167962_+	acyl-CoA thioesterase II	NA	NA	NA	NA
WP_173173535.1\|1168336_1168819_-	Bro-N domain-containing protein	NA	NA	NA	NA
WP_173173533.1\|1169530_1170070_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_173173531.1\|1170146_1170674_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA

DBSCAN-SWA_3

2890088 : 2897095

uncultured_Caudovirales_phage(85.71%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_173174257.1\|2890088_2891369_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	5.1e-100	55.1
WP_173174255.1\|2891485_2892880_+	uroporphyrinogen-III C-methyltransferase	NA	NA	NA	NA
WP_173174253.1\|2892867_2893869_-	glutathione S-transferase C-terminal domain-containing protein	NA	NA	NA	NA
WP_173174251.1\|2893956_2894940_-	glycosyl transferase family protein	A0A2H4JBY5	uncultured_Caudovirales_phage	6.2e-138	73.6
WP_173174249.1\|2894936_2895272_-	TusE/DsrC/DsvC family sulfur relay protein	A0A2H4J8B6	uncultured_Caudovirales_phage	9.1e-41	75.7
WP_173174247.1\|2895268_2895571_-	sulfurtransferase complex subunit TusB	A0A2H4JG28	uncultured_Caudovirales_phage	4.5e-23	53.0
WP_173174245.1\|2895570_2895930_-	sulfurtransferase complex subunit TusC	A0A2H4J8C0	uncultured_Caudovirales_phage	2.2e-32	58.3
WP_173174243.1\|2895930_2896323_-	sulfurtransferase complex subunit TusD	A0A2H4JA39	uncultured_Caudovirales_phage	7.9e-52	78.3
WP_111262163.1\|2896426_2897095_-	Bax inhibitor-1/YccA family protein	A0A2H4JFM9	uncultured_Caudovirales_phage	1.8e-96	84.3

DBSCAN-SWA_4

4689364 : 4713948

Haemophilus_phage(37.5%)

tail,holin,plate,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_173172363.1\|4689364_4689625_-	hypothetical protein	A0A248XCT8	Klebsiella_phage	3.4e-11	47.7
WP_173172361.1\|4689621_4690005_-	hypothetical protein	NA	NA	NA	NA
WP_173172359.1\|4690001_4690631_-	glycoside hydrolase family 19 protein	A0A125RNP1	Pseudomonas_phage	1.7e-64	60.8
WP_173172357.1\|4690738_4692046_-	hypothetical protein	A0A077K818	Ralstonia_phage	4.0e-39	53.7
WP_173172355.1\|4692304_4692802_-	DUF4376 domain-containing protein	A0A2H4JF49	uncultured_Caudovirales_phage	6.6e-27	53.9
WP_173172353.1\|4692801_4694769_-\|tail	tail fiber protein	A0A1L7DQU7	Yersinia_phage	2.4e-48	46.7
WP_173172351.1\|4695009_4695507_-	DUF4376 domain-containing protein	A0A2H4JF49	uncultured_Caudovirales_phage	2.4e-29	54.3
WP_173172349.1\|4695506_4697147_-\|tail	tail fiber protein	A9DEL7	Yersinia_phage	1.2e-37	38.4
WP_173172347.1\|4697143_4697782_-	DUF2612 domain-containing protein	D0UIH4	Aggregatibacter_phage	2.8e-46	50.0
WP_173172345.1\|4697778_4698924_-\|plate	baseplate J/gp47 family protein	Q7Y5S4	Haemophilus_phage	4.3e-98	52.1
WP_173172343.1\|4698989_4699343_-	hypothetical protein	Q7Y5S5	Haemophilus_phage	1.2e-30	58.0
WP_173172340.1\|4699353_4699995_-	hypothetical protein	D0UIH7	Aggregatibacter_phage	1.3e-40	41.7
WP_173172338.1\|4699987_4700848_-	hypothetical protein	D0UIH8	Aggregatibacter_phage	3.6e-65	47.3
WP_173172336.1\|4700844_4701162_-	hypothetical protein	Q7Y5S9	Haemophilus_phage	2.5e-24	49.5
WP_173172333.1\|4701158_4701911_-	hypothetical protein	Q7Y5T0	Haemophilus_phage	2.7e-32	37.3
WP_173172331.1\|4701926_4703345_-	hypothetical protein	Q7Y5T2	Haemophilus_phage	1.3e-19	28.7
WP_173171722.1\|4703361_4703526_-	hypothetical protein	Q776V6	Haemophilus_phage	1.1e-07	52.4
WP_173172329.1\|4703522_4703930_-	hypothetical protein	Q776V6	Haemophilus_phage	1.0e-22	44.4
WP_173172327.1\|4703932_4704364_-	DUF3277 family protein	Q7Y5T4	Haemophilus_phage	1.4e-33	47.9
WP_173172325.1\|4704426_4705926_-	DUF3383 family protein	Q7Y5T5	Haemophilus_phage	2.3e-139	53.5
WP_175384278.1\|4705927_4706461_-	hypothetical protein	NA	NA	NA	NA
WP_173172323.1\|4706561_4706837_-\|holin	phage holin family protein	H2BD74	Pseudomonas_phage	1.0e-13	46.2
WP_111261889.1\|4706829_4707204_-	hypothetical protein	A0A0S2SYH4	Pseudomonas_phage	5.4e-26	51.6
WP_173172321.1\|4707373_4707904_-	hypothetical protein	NA	NA	NA	NA
WP_173172318.1\|4708095_4708806_+	helix-turn-helix domain-containing protein	A0A1B0VRI7	Pseudomonas_phage	1.0e-57	49.0
WP_003283978.1\|4709616_4709802_-	carbon storage regulator CsrA	A0A2I7RT00	Vibrio_phage	9.9e-13	68.6
WP_111261886.1\|4709989_4711225_-	aspartate kinase	NA	NA	NA	NA
WP_173172316.1\|4711326_4713948_-\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	1.8e-75	38.7

DBSCAN-SWA_5

5060600 : 5129412

Pseudomonas_phage(48.57%)

protease,head,terminase,portal,tRNA,lysis

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_173171761.1\|5060600_5061659_-\|tRNA	tRNA pseudouridine(13) synthase TruD	NA	NA	NA	NA
WP_173171759.1\|5061655_5062129_-	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	NA	NA	NA	NA
WP_173171757.1\|5062242_5063088_-	S-formylglutathione hydrolase	NA	NA	NA	NA
WP_111261651.1\|5063162_5064275_-	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase	E3SJ82	Synechococcus_phage	2.8e-33	29.3
WP_173171755.1\|5064379_5065291_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_173171753.1\|5065266_5065977_-	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_111261654.1\|5065973_5066255_-	cell division protein FtsB	NA	NA	NA	NA
WP_111261655.1\|5066315_5067605_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	2.6e-136	58.3
WP_173171751.1\|5067752_5068598_-	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	1.6e-49	41.6
WP_173171748.1\|5068601_5070233_-	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	1.4e-155	53.1
WP_173171746.1\|5070398_5071772_-\|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA
WP_111261658.1\|5071758_5072709_-	acetyl-CoA carboxylase carboxyl transferase subunit alpha	NA	NA	NA	NA
WP_173171744.1\|5072818_5076343_-	DNA polymerase III subunit alpha	A0A291AVA6	Streptomyces_phage	1.7e-198	36.6
WP_173171742.1\|5076484_5077087_-	ribonuclease HII	R4THQ2	Phaeocystis_globosa_virus	6.7e-18	35.3
WP_173171740.1\|5077086_5078220_-	lipid-A-disaccharide synthase	NA	NA	NA	NA
WP_111261662.1\|5078224_5079001_-	acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase	NA	NA	NA	NA
WP_031287666.1\|5078997_5079438_-	3-hydroxyacyl-ACP dehydratase FabZ	NA	NA	NA	NA
WP_173171738.1\|5079486_5080545_-	UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase	NA	NA	NA	NA
WP_031287668.1\|5080546_5081050_-	OmpH family outer membrane protein	NA	NA	NA	NA
WP_111261664.1\|5081093_5083445_-	outer membrane protein assembly factor BamA	NA	NA	NA	NA
WP_173171736.1\|5083519_5084869_-\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_173171734.1\|5084884_5086075_-	1-deoxy-D-xylulose-5-phosphate reductoisomerase	NA	NA	NA	NA
WP_173171732.1\|5086071_5086887_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_111261668.1\|5086889_5087636_-	di-trans,poly-cis-decaprenylcistransferase	R9W0U9	Flavobacterium_phage	4.4e-19	38.1
WP_111261669.1\|5087648_5088206_-	ribosome recycling factor	NA	NA	NA	NA
WP_111261670.1\|5088202_5088946_-	UMP kinase	NA	NA	NA	NA
WP_173171730.1\|5089147_5090017_-	elongation factor Ts	NA	NA	NA	NA
WP_111261672.1\|5090143_5090887_-	30S ribosomal protein S2	NA	NA	NA	NA
WP_111261673.1\|5091155_5091938_+	type I methionyl aminopeptidase	NA	NA	NA	NA
WP_173171728.1\|5091976_5094679_+	[protein-PII] uridylyltransferase	NA	NA	NA	NA
WP_173171726.1\|5094719_5095913_+	succinyldiaminopimelate transaminase	NA	NA	NA	NA
WP_173171724.1\|5096233_5096746_-\|lysis	lysis protein	Q8W6S5	Burkholderia_virus	8.6e-06	33.1
WP_173180447.1\|5096742_5097219_-	hypothetical protein	A0A2H4JFP9	uncultured_Caudovirales_phage	2.0e-41	57.0
WP_173180446.1\|5097260_5097554_-	hypothetical protein	NA	NA	NA	NA
WP_173180445.1\|5097676_5098294_-	hypothetical protein	NA	NA	NA	NA
WP_173180444.1\|5098293_5099016_-\|head	head decoration protein	A0A2D1ADT9	Rhodococcus_phage	1.3e-47	47.7
WP_173180443.1\|5099025_5099349_-	hypothetical protein	A0A1B1IQ35	uncultured_Mediterranean_phage	7.5e-08	47.5
WP_175384279.1\|5099341_5099926_-	hypothetical protein	A0A0U4B0K9	Pseudomonas_phage	6.3e-37	39.4
WP_175384280.1\|5099952_5100915_-	hypothetical protein	NA	NA	NA	NA
WP_173180435.1\|5100905_5102279_-	hypothetical protein	NA	NA	NA	NA
WP_173180448.1\|5102275_5102683_-	hypothetical protein	NA	NA	NA	NA
WP_173180449.1\|5102683_5104444_-	hypothetical protein	A0A0U4JP39	Pseudomonas_phage	2.7e-107	39.8
WP_175384281.1\|5104443_5104950_-	hypothetical protein	A0A1W6JT98	Pseudomonas_phage	6.2e-41	48.8
WP_173180426.1\|5104959_5108112_-	tape measure protein	A0A0U3TH20	Pseudomonas_phage	3.6e-94	39.7
WP_173180425.1\|5108212_5108515_-	hypothetical protein	NA	NA	NA	NA
WP_173180424.1\|5108569_5108998_-	hypothetical protein	NA	NA	NA	NA
WP_173180423.1\|5109145_5109757_+	hypothetical protein	NA	NA	NA	NA
WP_173180422.1\|5109830_5110610_-	hypothetical protein	A0A1W6JT83	Pseudomonas_phage	5.2e-87	66.4
WP_173180421.1\|5110613_5110802_-	hypothetical protein	NA	NA	NA	NA
WP_173180410.1\|5110798_5111284_-	hypothetical protein	A0A1W6JT75	Pseudomonas_phage	1.5e-23	38.9
WP_173180409.1\|5111280_5111598_-	hypothetical protein	NA	NA	NA	NA
WP_173180408.1\|5111601_5111955_-	DUF2190 family protein	NA	NA	NA	NA
WP_173180407.1\|5111987_5112218_-	hypothetical protein	A0A1S6UB66	Serratia_phage	3.5e-15	56.3
WP_173180406.1\|5112275_5114225_-\|head	Mu-like prophage major head subunit gpT family protein	A0A2I7QRU0	Vibrio_phage	1.5e-90	33.8
WP_173180405.1\|5114232_5115738_-\|portal	phage portal protein	Q75QM9	Wolbachia_phage	2.0e-74	36.1
WP_173180404.1\|5115739_5115943_-	hypothetical protein	NA	NA	NA	NA
WP_173180403.1\|5115942_5117898_-\|terminase	phage terminase large subunit family protein	A0A1B0Z2K0	Pseudomonas_phage	1.7e-280	69.3
WP_173180402.1\|5117869_5118415_-\|terminase	terminase small subunit	A0A1B0Z033	Pseudomonas_phage	1.4e-54	66.3
WP_173176265.1\|5118527_5119316_-	hypothetical protein	A0A1W6JTE1	Pseudomonas_phage	1.1e-65	52.7
WP_173176263.1\|5119319_5119553_-	hypothetical protein	A0A0H5AWC3	Pseudomonas_phage	1.6e-12	44.3
WP_173176261.1\|5119555_5119849_-	hypothetical protein	A0A125RNL4	Pseudomonas_phage	9.8e-15	50.6
WP_021217129.1\|5119851_5120160_-	hypothetical protein	A0A1B0VME9	Pseudomonas_phage	1.7e-17	51.9
WP_111261794.1\|5120366_5120942_-	hypothetical protein	H2BDI9	Pseudomonas_virus	1.0e-63	62.5
WP_173176259.1\|5120953_5121250_-	hypothetical protein	A0A2D1GNG3	Pseudomonas_phage	1.5e-15	50.5
WP_173176257.1\|5121279_5121708_-	VRR-NUC domain-containing protein	A0A2D1GNH3	Pseudomonas_phage	3.8e-39	63.0
WP_173176254.1\|5121697_5122000_-	hypothetical protein	NA	NA	NA	NA
WP_173176279.1\|5121996_5122353_-	recombinase	NA	NA	NA	NA
WP_173176277.1\|5122352_5122568_-	hypothetical protein	NA	NA	NA	NA
WP_111261792.1\|5122572_5123352_-	hypothetical protein	A0A1B0VMD9	Pseudomonas_phage	1.5e-57	51.1
WP_173176252.1\|5123338_5124217_-	helix-turn-helix domain-containing protein	A0A0U4IBP5	Pseudomonas_phage	9.4e-45	51.2
WP_173176250.1\|5124213_5124828_-	hypothetical protein	NA	NA	NA	NA
WP_173176248.1\|5124894_5125131_-	hypothetical protein	A0A2H4J0V8	uncultured_Caudovirales_phage	1.8e-14	55.1
WP_173176275.1\|5125216_5125900_+	repressor protein c2	A5VW98	Enterobacteria_phage	1.2e-39	46.4
WP_173176246.1\|5125942_5126821_+	hypothetical protein	NA	NA	NA	NA
WP_173176244.1\|5127086_5127470_+	hypothetical protein	NA	NA	NA	NA
WP_173176242.1\|5127511_5127703_-	hypothetical protein	NA	NA	NA	NA
WP_173176240.1\|5127833_5128505_+	SOS response-associated peptidase family protein	A0A2H4J991	uncultured_Caudovirales_phage	2.3e-75	60.2
WP_173176238.1\|5128501_5128741_-	hypothetical protein	NA	NA	NA	NA
WP_173176236.1\|5128878_5129412_+	hypothetical protein	A0A2K8HVM8	Pseudomonas_phage	2.1e-10	31.4

DBSCAN-SWA_6

5132471 : 5142693

Pseudomonas_phage(50.0%)

integrase

attL 5129607:5129622|attR 5140230:5140245

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
5129607:5129622	attL	NA	NA	NA	NA
WP_173176220.1\|5132471_5133326_+	phosphoadenosine phosphosulfate reductase family protein	A0A1P8VV89	Erythrobacter_phage	2.3e-40	37.9
WP_173176218.1\|5133328_5134771_+	DNA cytosine methyltransferase	A0A2I7R2G4	Vibrio_phage	2.8e-110	48.1
WP_173176216.1\|5134820_5135399_+	DUF4406 domain-containing protein	V5JVS6	Pseudomonas_phage	4.2e-33	68.1
WP_173176214.1\|5135395_5135830_+	hypothetical protein	NA	NA	NA	NA
WP_173176212.1\|5135833_5136037_+	hypothetical protein	NA	NA	NA	NA
WP_173176210.1\|5136033_5137335_+	Lar family restriction alleviation protein	H2BD37	Pseudomonas_phage	1.6e-08	52.9
WP_173176273.1\|5137325_5137634_+	hypothetical protein	A0A0S2SY28	Pseudomonas_phage	3.1e-35	68.8
WP_173176208.1\|5137630_5138158_+	hypothetical protein	NA	NA	NA	NA
WP_173176206.1\|5138157_5138487_+	hypothetical protein	A0A088C3G3	Shewanella_sp._phage	8.2e-18	55.8
WP_173176204.1\|5138553_5138793_+	excisionase	NA	NA	NA	NA
WP_173176202.1\|5138773_5139883_+\|integrase	phage integrase Arm DNA-binding domain-containing protein	A0A0U4JIT5	Pseudomonas_phage	1.4e-130	64.6
WP_173176200.1\|5139951_5140299_+	ArsC family reductase	NA	NA	NA	NA
5140230:5140245	attR	NA	NA	NA	NA
WP_173176198.1\|5140377_5141412_+	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	NA	NA	NA	NA
WP_173176196.1\|5141487_5142693_+	aminotransferase class V-fold PLP-dependent enzyme	Q2XUY6	environmental_halophage	1.0e-73	38.3

DBSCAN-SWA_7

6277507 : 6311303

Pseudomonas_phage(71.43%)

head,holin,terminase,integrase,portal,tail,lysis

attL 6263597:6263613|attR 6308413:6308429

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
6263597:6263613	attL	NA	NA	NA	NA
WP_173170934.1\|6277507_6278047_-\|lysis	lysis protein	NA	NA	NA	NA
WP_173180447.1\|6278043_6278520_-	hypothetical protein	A0A2H4JFP9	uncultured_Caudovirales_phage	2.0e-41	57.0
WP_173180446.1\|6278561_6278855_-	hypothetical protein	NA	NA	NA	NA
WP_173180445.1\|6278977_6279595_-	hypothetical protein	NA	NA	NA	NA
WP_173180444.1\|6279594_6280317_-\|head	head decoration protein	A0A2D1ADT9	Rhodococcus_phage	1.3e-47	47.7
WP_173180443.1\|6280326_6280650_-	hypothetical protein	A0A1B1IQ35	uncultured_Mediterranean_phage	7.5e-08	47.5
WP_175384285.1\|6280642_6281227_-	hypothetical protein	A0A1B0Z051	Pseudomonas_phage	4.8e-37	40.9
WP_175384286.1\|6281253_6282216_-	hypothetical protein	NA	NA	NA	NA
WP_173180435.1\|6282206_6283580_-	hypothetical protein	NA	NA	NA	NA
WP_173180436.1\|6283576_6283984_-	hypothetical protein	NA	NA	NA	NA
WP_173180437.1\|6283984_6285745_-	hypothetical protein	A0A0U4JP39	Pseudomonas_phage	6.4e-109	40.4
WP_175384287.1\|6285744_6286251_-	hypothetical protein	A0A1W6JT98	Pseudomonas_phage	6.9e-40	48.3
WP_173180420.1\|6286260_6289554_-\|tail	phage tail tape measure protein	K4ICR4	Acidithiobacillus_phage	2.1e-44	34.4
WP_173180419.1\|6289576_6289714_-	hypothetical protein	NA	NA	NA	NA
WP_173180418.1\|6289749_6290220_-	hypothetical protein	NA	NA	NA	NA
WP_173180417.1\|6290254_6290743_-	hypothetical protein	NA	NA	NA	NA
WP_021217429.1\|6290849_6291101_-	hypothetical protein	NA	NA	NA	NA
WP_111261777.1\|6291188_6291968_-	hypothetical protein	A0A1W6JT83	Pseudomonas_phage	2.8e-80	62.6
WP_021216891.1\|6291971_6292160_-	hypothetical protein	NA	NA	NA	NA
WP_173180410.1\|6292156_6292642_-	hypothetical protein	A0A1W6JT75	Pseudomonas_phage	1.5e-23	38.9
WP_173180409.1\|6292638_6292956_-	hypothetical protein	NA	NA	NA	NA
WP_173180408.1\|6292959_6293313_-	DUF2190 family protein	NA	NA	NA	NA
WP_173180407.1\|6293345_6293576_-	hypothetical protein	A0A1S6UB66	Serratia_phage	3.5e-15	56.3
WP_173180406.1\|6293633_6295583_-\|head	Mu-like prophage major head subunit gpT family protein	A0A2I7QRU0	Vibrio_phage	1.5e-90	33.8
WP_173180405.1\|6295590_6297096_-\|portal	phage portal protein	Q75QM9	Wolbachia_phage	2.0e-74	36.1
WP_173180404.1\|6297097_6297301_-	hypothetical protein	NA	NA	NA	NA
WP_173180403.1\|6297300_6299256_-\|terminase	phage terminase large subunit family protein	A0A1B0Z2K0	Pseudomonas_phage	1.7e-280	69.3
WP_173180402.1\|6299227_6299773_-\|terminase	terminase small subunit	A0A1B0Z033	Pseudomonas_phage	1.4e-54	66.3
WP_173178645.1\|6299903_6300692_-	hypothetical protein	A0A1W6JTE1	Pseudomonas_phage	1.3e-56	48.6
WP_173178644.1\|6300688_6301018_-\|holin	phage holin family protein	A0A0U4J8T9	Pseudomonas_phage	7.2e-14	49.5
WP_021217629.1\|6301010_6301382_-	membrane protein	Q9MC43	Pseudomonas_phage	3.4e-20	47.1
WP_173178643.1\|6301573_6302119_-	hypothetical protein	A0A0A0YRV6	Pseudomonas_phage	1.4e-51	68.6
WP_173178642.1\|6302115_6302322_-	hypothetical protein	NA	NA	NA	NA
WP_173178641.1\|6302318_6302615_-	hypothetical protein	A0A1W6JTC1	Pseudomonas_phage	1.9e-21	62.0
WP_173178640.1\|6302614_6303934_-\|integrase	tyrosine-type recombinase/integrase	A0A2D1GND4	Pseudomonas_phage	9.3e-105	46.2
WP_173178639.1\|6303930_6304329_-	hypothetical protein	A0A0A0YQ44	Pseudomonas_phage	4.3e-21	58.2
WP_173178638.1\|6304325_6305729_-	AAA family ATPase	A0A2H4J8N1	uncultured_Caudovirales_phage	1.0e-117	50.6
WP_173178637.1\|6305725_6306535_-	ATP-binding protein	A0A1W6JTD8	Pseudomonas_phage	5.3e-58	46.6
WP_173178636.1\|6306521_6306767_-	hypothetical protein	A0A0A0YR83	Pseudomonas_phage	1.9e-11	60.7
WP_173178635.1\|6307288_6307588_-	hypothetical protein	NA	NA	NA	NA
WP_173178634.1\|6308399_6308660_-	hypothetical protein	NA	NA	NA	NA
6308413:6308429	attR	NA	NA	NA	NA
WP_173178633.1\|6308656_6308899_-	hypothetical protein	A0A0A0YRU7	Pseudomonas_phage	1.6e-10	48.6
WP_173178632.1\|6308891_6309215_-	hypothetical protein	NA	NA	NA	NA
WP_173178631.1\|6309805_6310567_+	helix-turn-helix domain-containing protein	W6MVG5	Pseudomonas_phage	7.6e-51	49.5
WP_173178630.1\|6310696_6311068_+	response regulator transcription factor	A0A1W6JTA9	Pseudomonas_phage	1.6e-14	44.0
WP_173178629.1\|6311069_6311303_+	hypothetical protein	A0A0A0YQ28	Pseudomonas_phage	1.2e-15	55.8

DBSCAN-SWA_8

6315894 : 6323914

Enterobacteria_phage(50.0%)

integrase

attL 6314204:6314219|attR 6331360:6331375

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
6314204:6314219	attL	NA	NA	NA	NA
WP_173178618.1\|6315894_6317046_+\|integrase	integrase	V9IQN0	Stenotrophomonas_phage	8.0e-76	41.4
WP_173178617.1\|6317345_6318410_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	5.6e-100	54.2
WP_173178616.1\|6318406_6319279_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	6.0e-108	66.7
WP_173178615.1\|6319275_6319821_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	1.4e-51	56.4
WP_173178614.1\|6319817_6320684_+	dTDP-4-dehydrorhamnose reductase	A0A1D7XFA3	Escherichia_phage	9.4e-29	34.4
WP_173178613.1\|6320732_6322544_+	GHKL domain-containing protein	NA	NA	NA	NA
WP_173178612.1\|6322540_6323914_+	sigma 54-interacting transcriptional regulator	W8CYM9	Bacillus_phage	8.5e-08	30.4
6331360:6331375	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_AP023189

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection