CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP040605	Saccharopolyspora sp. ASAGF58 chromosome, complete genome	24 crisprs	c2c9_V-U4,WYL,cas4,casR,csa3,cas3,RT,Cas14u_CAS-V,DinG,DEDDh,Cas9_archaeal,cas14j	13	20	15	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP040605_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_1

24003-24083

Orphan

Consensus_repeat	Method
GCGGTGGTGGTGTGCCCGGCCGGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040605_1

>merge|NZ_CP040605|1|24003-24083|CRISPRCasFinder
GCGGTGGTGGTGTGCCCGGCCGGTCCGGGTCAACACCCGGTACCCCACCGGAATACGCGGGTGGTGGTGTGCCCGGCCGGT

>NZ_CP040605|1|1|24003-24083|CRISPRCasFinder
GCGGTGGTGGTGTGCCCGGCCGGT	CCGGGTCAACACCCGGTACCCCACCGGAATACG
CGGGTGGTGGTGTGCCCGGCCGGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168584070.1\|25821_26067_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168584157.1\|40444_42019_-\|PfaD-family-polyunsaturated-fatty-acid/polyketide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|240093
NZ_CP040605.1\|WP_168584153.1\|26603_26777_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168584161.1\|49597_51442_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235136
NZ_CP040605.1\|WP_168584154.1\|27065_27683_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP040605.1\|WP_168584160.1\|47949_49464_+\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224983
NZ_CP040605.1\|WP_168584155.1\|27928_34402_-\|beta-keto-acyl-synthase	unknown	unknown	gnl\|CDD\|238429
NZ_CP040605.1\|WP_168584152.1\|1380_2715_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168584156.1\|34407_40371_-\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274311
NZ_CP040605.1\|WP_168584158.1\|42018_45543_-\|NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|163707
NZ_CP040605.1\|WP_168584159.1\|45535_47335_-\|fatty-acyl-AMP-ligase	unknown	unknown	gnl\|CDD\|341254

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168584154.1\|27065_27683_+\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	9.09729e-23
NZ_CP040605.1\|WP_168584161.1\|49597_51442_-\|hypothetical-protein	gnl\|CDD\|235136	PRK03598, PRK03598, putative efflux pump membrane fusion protein; Provisional.	0.00477921
NZ_CP040605.1\|WP_168584159.1\|45535_47335_-\|fatty-acyl-AMP-ligase	gnl\|CDD\|341254	cd05931, FAAL, Fatty acyl-AMP ligase (FAAL). FAAL belongs to the class I adenylate forming enzyme family and is homologous to fatty acyl-coenzyme A (CoA) ligases (FACLs). However, FAALs produce only the acyl adenylate and are unable to perform the thioester-forming reaction, while FACLs perform a two-step catalytic reaction; AMP ligation followed by CoA ligation using ATP and CoA as cofactors. FAALs have insertion motifs between the N-terminal and C-terminal subdomains that distinguish them from the FACLs. This insertion motif precludes the binding of CoA, thus preventing CoA ligation. It has been suggested that the acyl adenylates serve as substrates for multifunctional polyketide synthases to permit synthesis of complex lipids such as phthiocerol dimycocerosate, sulfolipids, mycolic acids, and mycobactin.	0
NZ_CP040605.1\|WP_168584160.1\|47949_49464_+\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224983	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism].	4.49762e-95
NZ_CP040605.1\|WP_168584155.1\|27928_34402_-\|beta-keto-acyl-synthase	gnl\|CDD\|238429	cd00833, PKS, polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or more large multifunctional proteins and iterative type II PKSs, complexes of several monofunctional subunits.	1.23708e-117
NZ_CP040605.1\|WP_168584157.1\|40444_42019_-\|PfaD-family-polyunsaturated-fatty-acid/polyketide-biosynthesis-protein	gnl\|CDD\|240093	cd04742, NPD_FabD, 2-Nitropropane dioxygenase (NPD)-like domain, associated with the (acyl-carrier-protein) S-malonyltransferase FabD. NPD is part of the nitroalkaneoxidizing enzyme family, that catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDPs are members of the NAD(P)H-dependent flavin oxidoreductase family that reduce a range of alternative electron acceptors. Most use FAD/FMN as a cofactor and NAD(P)H as electron donor. Some contain 4Fe-4S cluster to transfer electron from FAD to FMN.	0
NZ_CP040605.1\|WP_168584156.1\|34407_40371_-\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|274311	TIGR02813, omega-3_polyunsaturated_fatty_acid_synthase_PfaA, polyketide-type polyunsaturated fatty acid synthase PfaA. Members of the seed for this alignment are involved in omega-3 polyunsaturated fatty acid biosynthesis, such as the protein PfaA from the eicosapentaenoic acid biosynthesis operon in Photobacterium profundum strain SS9. PfaA is encoded together with PfaB, PfaC, and PfaD, and the functions of the individual polypeptides have not yet been described. More distant homologs of PfaA, also included with the reach of this model, appear to be involved in polyketide-like biosynthetic mechanisms of polyunsaturated fatty acid biosynthesis, an alternative to the more familiar iterated mechanism of chain extension and desaturation, and in most cases are encoded near genes for homologs of PfaB, PfaC, and/or PfaD.	0
NZ_CP040605.1\|WP_168584158.1\|42018_45543_-\|NAD(P)-binding-protein	gnl\|CDD\|163707	cd08151, AOS, Allene oxide synthase. Allene oxide synthase converts a fatty acid hydroperoxide to an allene oxide, which is an unstable epoxide. In corals, the enzyme is part of a eiconaosid synthesis pathway that is initiated by a lipoxygenase, which generates the fatty acid hydroperoxides in the first step. The structure of allene oxide synthase closely resembles that of catalase, but allene oxide synthase does not have catalase activity.	3.53452e-49

>NZ_CP040605.1|WP_168584152.1|1380_2715_-|hypothetical-protein
MPLRDVVALVEAKYHDLGPEHRDQVMEFSRALADMLRTRRSEPVIHAGAGPAQPSSVEPAPASVPFGELKPLRDPVDAWGSEPRGGDAEDGRDGSRGSLPDVVDDRPVLGAGDLAGVSEEVRAALAAFQAATGVAAAPRLADVDGHNVLAHLRVLGWLGVVDRAVVVKKTTWRASMGQSSDPDAPVLVKESIDAWYVMGEHAPGARPDIAMRPEDLRSPLSQRAPDRSVKFFVHVVDPAGVRVEYGLADPGLWRRGREVEWGGLFAAVQDEGRPAELMNRVNPAVRESRYLAQALGVDEATAQVWRMWSHLPEGHAEALRRAIIGSTVSTYGGREAVKALVEELVPPGERTGERLQVLGQFMVRLADRRRRLGRWARKGVPHRVSPAARLSTATNCGMRWTGSVAWTRWCVPGAGPTSGCRCRCSRVRHRSVPVSQAGSPASGS
>NZ_CP040605.1|WP_168584070.1|25821_26067_+|hypothetical-protein
MQALADPPGVGTAETVRRWVRHSETDTAARAGVASEKSAESQRLRRENTEVKRDNAILKRDNAILTAASAFFAAEIDRPHR
>NZ_CP040605.1|WP_168584153.1|26603_26777_+|hypothetical-protein
MALHVGSPTAQAGDLHLPAHHTGHRLAFSRSRGVAVGPAAAAELRSAGTVVETVKRL
>NZ_CP040605.1|WP_168584154.1|27065_27683_+|response-regulator-transcription-factor
MDQVRVAVQAADPITVAGLTSYLKSRSELLLVPSPAEADVIVFAADPVNSKVLAELRKSAQQVPVPRVLVTNELDPSNVLRVVEARVVAVLPRTAATGTRLVNSVIAAARGGAVMPPDLLGELLKQVDHLQREVLTPKGLNASGLTNREADVLRLMAGGLDTAEIAQKLCYSERTVKNVIYGLTSRLNLRNRPHAVAFAMRAGAI
>NZ_CP040605.1|WP_168584155.1|27928_34402_-|beta-keto-acyl-synthase
MFEPIAIVGRGCVLPGALDPDTFWDNIIERRVSLTRVPEGRWRLPAGDVPLGISSDIGGYVSGFAGVFDPDGLQVDAARIGVLDESYRWVLHGVRQALGEAGVGQPRERAGLVLGNLSLPTDGMVRFAESVWLSDQTPAVRAVLSGLLDGPEPSALNRFSSGIPAHFAAAALGLGAGAFALDAACASSLYAIKLACDRLHDGTADLMVAGAVNRTDDLAIHQAFSALSALSPTGRSRPFHRDADGLVPAEGAAFVALMRLSDALAAGVRIRGVIRGVGLSNDGRSKGILVPTEEGQVRALQQAYADAEISPESVSLLECHATGTSLGDAVEVRSTSRAFAGARDLPIGSAKSNTGHLITAAGAAGVLKVLAAMDAGIRPPTLGADEPVEALRDTPLRLLHEAEAWEGLRRAGISAFGFGGNNAHLVLEQWTGDNVVVSAKTASGPSSHSRPDEVAIVGIGARVADCADFDEFRDALLRGTPRLSPAVDYAVAVPELRVPPADLQKALGQQVSILEAAREAVRDVSLVRDRTMVLVGMGCDAEVARYPTRTRVASNLGESDLRERYPDAFAPVLDASAVVGTMPNVVANRINAQLDLAGPSFTVSAEEASGLVALEIGERALRTREADAVLVGAVDLSHEQVHRKALADLNIDVPPGDAAVVLVLKRLDDARGDGDDILAVLTDPQPDVSLVVGDGAISMEIGDSISIEIADQQNQVTHRCRESFDPAGVFGVPHAAKGLLAVACAAVAVRHGAIPRIDQPADPRVDQSAGPRVDHPADPSVGRRSAAVAVSTLGSQERHLGLRADSAVAWIADDVGRLHVFSGADAATALAAARAGRETDTGPARLVVLASDQTQLHDRIGAAERWLAGQGLQPEGVAFRNEPIAGETAFVFSNGSASYPRMGREVMLALPDIRQRVEQRCGSLTELIGWAYAGTAPRALDQIWGASVLGQLHTEITRGLLGVKPTAVIGYSSGESSALVAMGAWRDVPRLVAEAEDSVVLTSALAGEFAAVRRAWRRHGVTGEKWAAYIVSASAEAVREAVAGEPAVHLMAMNAPGVSVLGGESEGCQRVLRRLGQPNALRLDYDIAAHVPEVDEVRREYWELHRRPTFDLPDVRFYSCATTEPYVVTAQNAADAVTAQAVGTIDFIGTVERAWRDGVRVFIEHGPRGLCTGWIQRILGDREHVAVALDSADGRSLRQLTRAVAELVAAGVIVDHERLLGALATGRPAPRPVVEAFATAAHPPPIVLPEPHPEQRMHPAPVLPSVGEMLAPVPDPAGEPLLPVRTPAPVRTPAPVQAPAPVRTPVERAALHADGEWHRIVASTHQEFLESHAQVHQQYLALLEKSRMVLMRRPGTPGRGEVQGTVDQARWSEAPLTQHPTGQLSGPVFGREQLVQLASGRISEVFGPEFRAQDGFRRQVRMPQPPMLLADRVTAIDAPRGRLGTGTIWTQTDVAADAWYLDPAGRMPAGLVIEAGQADLLLISWMGVDLLNRGERVYRLLGCELTFHGSPPMPGEMLDFDIHIDGHGDHGGMRLFFFHYDCRVDGELRLSVRGGQAGFFSDHELADTSGVLWDPAGETPEPARWLDEPQVVCSARSFAAEQVAAFAAGRPDDCFGPEWLCTQAHVRTPRIAGGKMQLLREVTEFDPAGGPWKRGYLRAETPVSAADWFFEGHFKDDPCMPGTLMYEGCLQAMAFYLAALGYTVDADGWRFEPVTGEPVAMRCRGQVTPDSRSITYEVFVTEVSAGPVPTLIADVLCTVDGVKAFHARRAGLRLVPDWPLATLVPVQDAEVGSGIFGRSGLLASAWGKPTDAFGPAFAPFDGVRRSARLPGPPYHFISRIVSVDAPQGAMTAGGQAVAEYDLPADAWYWAENGYPVMPLAVLMEVALQPCGWFASYAGCTLSSEEDLLFRNLDGSATILGEVDRSVQTLHTTVTLLDISRYSGTIIVSFAVDVEADGQRLLHASSVFGFFPTQAFAEQIGLPSASSERLSGDSCRELVPCDGHGSLRLAGPMLLVLDRITGYWPDGGKAGLGRVVAEKDVRPGEWYFKAHFFQDPVQPGSLGVEAMCQLLRFYMIDRGLGDGLTDPRFSLVTDRPLTWKYRGQVTPANQTVTVELDVLELGEDPDGRFAVADASLWVDGARIYHVPELALRVVEQNP
>NZ_CP040605.1|WP_168584156.1|34407_40371_-|SDR-family-NAD(P)-dependent-oxidoreductase
MPEARTRTMPPVAIVGVSALLPGSSDPGGFWRTVVTGEDQVTEVPATHWLVEDHYDPDPAAPDKTYAHRGAFLSPVPFDPLAHGIPPKVLEATDTSQLLALVAAEQLLSGLPGLSGVDRERVSVILGTSSLELLTTMGSRIQRPVWLKALRDSGIAEDQAQAICDRIAASYVPWQEASLPGLLSNVVAGRIANRFDLHGSNYTTDAACASSLAALSSGANELATGQADLVITGGVDTLNDPVMYTCFSKTPALSPTGDCRPFSDQADGMVLGEGIVLFAIRRLEDAERDGDRIHAVIRGIGTASDGRGSSIYAPVPEGQARALRRAYDSAGYGPETVELVEAHGTGTAAGDAAEFAGLRAVFGAAGRSDSQWCALGSVKSQIGHTKNAAGAAGLLKATLALSQKALPPTIKVDRPNPALGFAGSPFYLNTQARPWISDGSHPRRAAVSSFGFGGTDFHVTLEEYRPSPGSESRAPDLTRAASSELVLFSADSPQALVSACRASTGVSRPLAAIARETQGAFDHTAQSRLAIVATTEADLTAKLAETADRIEADPETALSAPRGVYYAPRRTDPGKLGLLFSGQGSQYVGMGAEVAMLHPAARSAWDSAAGISFDGVALHRLVFPPPAFTEDERAAQDRLLTRTEWAQPALAVQSLALLEVLRTLGVSPDAVAGHSFGELVALHVAGCYDAETLIRLARKRGELMRDAAASQGAMLAVAGSIDDVRSVVADLDDQLWVANHNAPKQVVVSGTTEAIDRLAKWLAEAGRAARKLNTAAAFHSPLMDSARAPLREFLTAVDVEPPRIDAYSNAEADRYPPDPDPIRDRLADHLQRPVRFVDQIETMHANGVRTFVEVGAGATLARLTSDILAGREHLSVSLDHARTDGVTALHEGLAQLAVRGIPLNFEALWCPFTPIEEPRMDEKPGMTVDLLGANYGKPYPPPGGAHELPPPNPPQQAKITTPVPEPVDEPVVQGHRPPPDWVPGEGHPSPSNLVRSAPHPVSDPWLDALRETQRQASEAHATYQRVMAETHLAFLRMSEAALGGLSSGGVPEAASGGFSSASVPEAAAVQPAVPPWGHAGYTVPQTPSPPPEPVGVPVPAADSVAPSYDAYDAYPASVENPVENPAAEPESSRVDVGLVLEVVAEKTGYPLSVLDAGMELESDLGIDSIKRVEILSAVRERVPGLAEVDPALLGAAGTLGEVAELLGAGDSGVVHVAAEPAVPQEIAPSDKPTELTRLAISARRAPAAGFALSGLIGASIAITEDGTGVAEPLAAELVEHGVRAFVTADVQGDTDGVIFLGGLRSGSADEAIGVNRDALRVARAMVAGRPETPRVFVTVQDTGGDFGLSGSAPERVWLGGVAALARTAAKEWPGTAVKAIDCERGGRSGVELARAIARELLTGGGVTDVGLTADGARTVLHHADAPFGDPWTDVIGPESVIVISGGARGVTAMAARALAAARKPKVVLLGRTPLAEEPSYLRGVSGEAAVREAVAEHLRTSGESTAPQRIRSETARVLSCREIRATLDALESCGSPARYLPVDVRDSAALTEALAEVRAQWGPITGVVHGAGVLADKTIKDKTDEQLDYVFGTKVGGLRTLLDVTADDPLDLLCVFSSVAACYGNAGQSDYAMANEVITQIAAAERAKRPGCLVRTIAWGPWDGGMVDASLADRLRASGVQLIPIEAGAKAFVDEVLGAREPVHVVCAAGGFPKAEPSAAGEIVVTDRSHPYLADHSVAGTTVVPVAMVLEWFTAAAHLAGTCETAALRDLDVLRKITLDHFAGDGDIVRITCEPGGSLVLHGTGELPHYRAKLDCGRTAVSTETTIERVVGAPRRWDIPARLHAFGDRPIYDGYLLFHGPAFQALRGVDGVSAAGAVGTVVGARVLGWPDEHRYTDPAAVDGGIQLATLWAQRALGTAALPMGVGEFRLHRPGMLDGAGTSIIRAGEVHSAHAECDLQLCAADGTPVAELHGLRLVARPDGAPSGR
>NZ_CP040605.1|WP_168584157.1|40444_42019_-|PfaD-family-polyunsaturated-fatty-acid/polyketide-biosynthesis-protein
MKMSSTTVPSVVQPGAQEPLADVVARIREEVRIVATPGNGIGAIVGDPRGRRVLATLPPLYPEWLGDRSFNEVHGTRFPYVAGEMANGIATAELVIAMARADMLGFFGAAGIPVPKVTATVQNLREALPDRQNWGVNVIHAPQNPAWERHLVDMLLREQVPAVSASAFMDLTPTVVQLAASGLRTDRSGRIVRGTRVFAKISRPEVAEKFIAPAPQRLLDELVVNGRITADEAELAKRVPVAEDITVEADSGGHTDNRPLASLLPRIMELRDALSTRFRHGRNVRIGAAGGLGTPHGVASALAAGAAYVLTGSVNQTCLEAGISAEAKEMLAAADIADVMMAPASDMFELGAKVQVLRKGTMFGPRANQLYQIYRQYRSFDEMPDREAEKLERSVLGATIADVWAETRRYWLERDPDELSRAEADPKHRMALVCRWYLGRSSWWAIHGETTRRADYQLWCGPATGAFNRWAAGSFLADPANRSVVQVARNLLEGAAVVTRAHQLRTYGVPVPATAFRFTPRRLT
>NZ_CP040605.1|WP_168584158.1|42018_45543_-|NAD(P)-binding-protein
MSSELLAPALRICTGPDDPRLHDVDADFTALLRKFQTAVTSTGKRLFHGAGACVRGHVEFVDGTGIAVHPFFAAGKRYPLIARYSNGESPDDIAPGTRGVSLLWLDPDGSRESPFSLTLNTGRALFAGNVAAFVRFLLGSDQDRQDMVEANPRAGELLWEQVRDPVSFMRYHYHSQAPRVHVDATGRPWLARYRLVPAEDSSDCGRHVAGHRVFPPVPPHFLPRSAADMRPPTALRDELVEQVSNGGFGALLQIQLHPVTDSTDGNQAALDPSVVWSAGYHTIARVRFDAVLDTETAKDLVFDPAQAPEGLGIALARSPFEAASVNHARALIYRTMHAARTAPVAARVAARVEGTVEARGTRDQVTGSRGPLTSTVCVVGAGPSGLTVARELERLGHTVVVLEREPVVGGKAVSIDVDGRAYDLGAHICTPRYERFAELAAEFGVDTEEATATYEYDADRWFRRSPGAAFFRRSEFSRYTQLREQSFPGIATAGLAHSAGTLVQPISEWVVGNDLLGMTDSLGSGYTASGYGYPHDDIPALYFVKHVEMTGLVSLGPRTTGHAGPFTVSGGFGRLWQRVADSLSDVRTGTRITSIERASGGVVVHTDSGPVHADSLVLSVPLDQVVDVLDATADERDIASRVRTIDYYTVLCRISGLPRAGMYLVRSKEAAPPPGHCVAYHNRYANTDVYTCYSYGARGLDTADIVRRLRADVAAMGGQVTEVLVAGRWPFMPHFSAADLKDGVLDRLERMQGDRQTYHVGSLLGFELIETNVAYAQDLARRYFAAPVADDSRGRGRLGAPRYQVRSGAELLEWLTRQLAAELGRPVAEIDPQAPLDDYGLDSLTATGLQAELSDWLGFRVPPTLLLEHPTLEAVARQLVMLMDGEHADTLDVERKPVLAVALTPPRPFFCVGGAVGAAHQLQALADDLGPGYPFYGLQAPGYDGGEPALKTVEELADRYLEDIYAVQPRGPYVIGGYSFGGLVAYEIGCRLRRDGAEVAGVVGIDSYLPRGGQTAPVWDERAALEELVAVHRAMSGAQGDALKVDPALTFAQCRELVIRELQIMGAAAADRLLDRLLPVFQSNLEANIAYRPQPSDLSMTLLRAVEPFPPVFGEARRPAITVGDPHNGWASVQMARLRVHEVPGNHFTIIGGADLRGLAATLRKVLDETLLEK
>NZ_CP040605.1|WP_168584159.1|45535_47335_-|fatty-acyl-AMP-ligase
MHLEVEPDPNPAPSLGAGTILAAFIDLHERDMDRELFVFVDDDGRDAESMTVRRLAHDAQRVMSLLAREGVRRGDRALLVYLPSLHFISAFLGCLACGVIPVPVAPPNPLKLAQDTGALAAVATSSGARVVLTHDAYQGAIDAALRARPLPPEAPQMPGIPWLATDSRHGGEVDVVEPRHWYNPADPDEPAFLQYTSGSTGFPKGVIVSHRNIGRELQFLAADLGLGDDTVAVTWVPHFHDLGLISFLLNTIAGHSGRTYVMSPLSFLQRPSVWFDVMSRVRATHTSAPNFAYDLMVRKTTPEQRAEWDLSSVRILGSSGEMVLPETMERFWNAFLPTGLRPAVFHPGYGMAEHTLSLSMGSGGQLWVDKRELEKGRVEPVEAGSTRDAAGFYGSGWVTKQDANVRIVDPGTGKPCDPGQVGEIWVDSPTKALGYWGLADETRETFRARVSDGDPREYLRTGDLGFFHNGELFVTGRLKELIIIRGDNYYPQDIEESVRRCHPLIRPGGVAAFSVPSAGSGQGERLIVFVETADGEPATGTAREVTQVVRRTVRDSYGIACDKVVVGAPGLVLKTTSGKVRRAACRTQYLQRLEEQPDE
>NZ_CP040605.1|WP_168584160.1|47949_49464_+|NAD(P)/FAD-dependent-oxidoreductase
MKQYLKVVIVGTGFGGLGQAIQLEKAGIRDYLVLEKADDVGGTWRDNSYPGCECDVESHLYSLSYEQKPDWSRNFAARSEIFAYLSNIADKHRLRSKIRFGVGLTAATWEPDRCRWRLNTTTGEELWCQFLISAVGGLHVPRLPELPGIETFTGPVWHSSQWNHDFDFAGKRVAVIGTGASGIQLVPPIAADAAKLYVFQRTPHWVLPKRNRDVPGWQRVLFKYIPGVQRVYRNRIYWRREMRALAFNGRLELWKGPESIAKQHIARHIKDSALREKLTPKYTMGCKRVLFSNDYYPALARDNVELITDSVADVRAGSVVDASGVEREIDAIIYATGFRITDALDYLHIIGTDRRFLAEEWATGGMRAHLGTTVAGFPNMFFLLGPNTAVTHTSVIFMLEAQARYVVNAIRLVDNSGAAALDVRRDVQEGFQTTIQQKLVKGVWTRGGCTNIYHDAAGVNRAIWPGFTWQFWLATRRVRREDYRLLHRAPQDRRLEASESTPAR
>NZ_CP040605.1|WP_168584161.1|49597_51442_-|hypothetical-protein
MSQDALSEVGLRNPGGDAQALYRSAQGWADLSAYLCEHSARVAEITGVGLQKWTGDAADAFTDRMRGVVHRAERMAQTTEVVAAQQEQHARKHVRVTQIIVELAVLIAATLAFYAAAAMFPALLAWAQAWLAYLVSTGVRVLQLLAQALRVLVDFLVRTRTWIAEVSQLTWKSERLSVGYGRILVEGVRDMGIDLAANLTASGLLGKKIDPAQVFISAGVSGLGGAFVGGLEKSGISKVLDGAGNARRGSDGLPEFVTFESQAKNFVMKIGPAPKQKPPNPPPSESERLLDNVKTAYDNAANLGIKDTPDAGRRLADELTLARNNHRNAVAEHTIAVDELSRAVTDVATRERAVLVHREAVDQAMQRVGAASTRLDLYRASGNPEWIQDGVQQLDAARRALAEASGGLREAQNALDTSRQGLLEWQRNVQTARDAVARSEAAHDLARFRADAWDQLDAARIAARDQTTFRQRLAFVRNNNAWGASFGSRNSWQEILFYDVPKDAINGMTSGAVKSGIEVARGNGQPGDMWKGVLLQGATGALRGGVNSAASNTAFPRSGVGETLWKTGSKTADIHARSSIEANTYGKASAGHHRKDVSRMPRPQGGEEARSTSA

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Crispr_ID: NZ_CP040605_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_2

86082-86221

Orphan

Consensus_repeat	Method
TCACGAGCCAGATAATCGGCCATTTCCCCCCGCACCGCCTC	CRISPRCasFinder

1 spacers

c2c9_V-U4

The CRISPR arrays of NZ_CP040605_2

>merge|NZ_CP040605|2|86082-86221|CRISPRCasFinder
TCACGAGCCAGATAATCGGCCATTTCCCCCCGCACCGCCTCGATCTCGTCGTGAGGCAGACCACTCACCACGACGCCAAGGTCACCAAGGTCACCAAGGTCACGGGCCAGATAATCGGCCATTTCCCCCCGCACCGCCTC

>NZ_CP040605|2|2|86082-86221|CRISPRCasFinder
TCACGAGCCAGATAATCGGCCATTTCCCCCCGCACCGCCTC	GATCTCGTCGTGAGGCAGACCACTCACCACGACGCCAAGGTCACCAAGGTCACCAAGG
TCACGGGCCAGATAATCGGCCATTTCCCCCCGCACCGCCTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168584073.1\|112739_112985_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168584165.1\|53734_54154_-\|cold-shock-domain-containing-protein	unknown	unknown	gnl\|CDD\|239905
NZ_CP040605.1\|WP_168584168.1\|56547_56811_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168584167.1\|55137_55755_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP040605.1\|WP_168584179.1\|119534_120752_+\|transposase	c2c9_V-U4	-	gnl\|CDD\|223747
NZ_CP040605.1\|WP_168584176.1\|116539_116995_-\|SsgA-family-sporulation/cell-division-regulator	unknown	unknown	gnl\|CDD\|377399
NZ_CP040605.1\|WP_168584174.1\|114077_114575_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|234711
NZ_CP040605.1\|WP_168584169.1\|57225_59295_+\|acetolactate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|236098
NZ_CP040605.1\|WP_168589696.1\|59335_60391_+\|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl\|CDD\|176245
NZ_CP040605.1\|WP_168584177.1\|117579_117723_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168584173.1\|71479_74416_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168584175.1\|116257_116455_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168584171.1\|61747_61987_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168589697.1\|118002_118641_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NZ_CP040605.1\|WP_168584178.1\|119131_119530_+\|IS200/IS605-family-transposase	unknown	unknown	gnl\|CDD\|376616
NZ_CP040605.1\|WP_168584072.1\|101159_112553_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223039
NZ_CP040605.1\|WP_168584180.1\|121738_123898_-\|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	unknown	unknown	gnl\|CDD\|224446
NZ_CP040605.1\|WP_168584170.1\|60399_61404_+\|3-oxoacyl-ACP-synthase	unknown	unknown	gnl\|CDD\|238426
NZ_CP040605.1\|WP_168584172.1\|62845_63493_-\|amino-acid-adenylation-domain-containing-protein	unknown	unknown	gnl\|CDD\|341253
NZ_CP040605.1\|WP_168584166.1\|54848_55043_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168584165.1\|53734_54154_-\|cold-shock-domain-containing-protein	gnl\|CDD\|239905	cd04458, CSP_CDS, Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. CSP expression is up-regulated by an abrupt drop in growth temperature. CSP's are also expressed under normal condition at lower level. The function of cold-shock proteins is not fully understood. They preferentially bind poly-pyrimidine region of single-stranded RNA and DNA. CSP's are thought to bind mRNA and regulate ribosomal translation, mRNA degradation, and the rate of transcription termination. The human Y-box protein, which contains a CSD, regulates transcription and translation of genes that contain the Y-box sequence in their promoters. This specific ssDNA-binding properties of CSD are required for the binding of Y-box protein to the promoter's Y-box sequence, thereby regulating transcription.	2.33441e-19
NZ_CP040605.1\|WP_168584176.1\|116539_116995_-\|SsgA-family-sporulation/cell-division-regulator	gnl\|CDD\|377399	pfam04686, SsgA, Streptomyces sporulation and cell division protein, SsgA. The precise function of SsgA is unknown. It has been found to be essential for spore formation, and to stimulate cell division.	1.29896e-27
NZ_CP040605.1\|WP_168584172.1\|62845_63493_-\|amino-acid-adenylation-domain-containing-protein	gnl\|CDD\|341253	cd05930, A_NRPS, The adenylation domain of nonribosomal peptide synthetases (NRPS). The adenylation (A) domain of NRPS recognizes a specific amino acid or hydroxy acid and activates it as an (amino) acyl adenylate by hydrolysis of ATP. The activated acyl moiety then forms a thioester bond to the enzyme-bound cofactor phosphopantetheine of a peptidyl carrier protein domain. NRPSs are large multifunctional enzymes which synthesize many therapeutically useful peptides in bacteria and fungi via a template-directed, nucleic acid independent nonribosomal mechanism. These natural products include antibiotics, immunosuppressants, plant and animal toxins, and enzyme inhibitors. NRPS has a distinct modular structure in which each module is responsible for the recognition, activation, and in some cases, modification of a single amino acid residue of the final peptide product. The modules can be subdivided into domains that catalyze specific biochemical reactions.	5.5511e-22
NZ_CP040605.1\|WP_168584179.1\|119534_120752_+\|transposase	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.78887e-33
NZ_CP040605.1\|WP_168584169.1\|57225_59295_+\|acetolactate-synthase-large-subunit	gnl\|CDD\|236098	PRK07789, PRK07789, acetolactate synthase 1 catalytic subunit; Validated.	0
NZ_CP040605.1\|WP_168584174.1\|114077_114575_+\|AAA-family-ATPase	gnl\|CDD\|234711	PRK00279, adk, adenylate kinase; Reviewed.	1.13686e-44
NZ_CP040605.1\|WP_168584167.1\|55137_55755_+\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	3.84598e-22
NZ_CP040605.1\|WP_168584180.1\|121738_123898_-\|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	gnl\|CDD\|224446	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion].	2.72953e-179
NZ_CP040605.1\|WP_168589697.1\|118002_118641_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	1.74747e-06
NZ_CP040605.1\|WP_168584178.1\|119131_119530_+\|IS200/IS605-family-transposase	gnl\|CDD\|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	4.56073e-54
NZ_CP040605.1\|WP_168589696.1\|59335_60391_+\|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl\|CDD\|176245	cd08285, NADP_ADH, NADP(H)-dependent alcohol dehydrogenases. This group is predominated by atypical alcohol dehydrogenases; they exist as tetramers and exhibit specificity for NADP(H) as a cofactor in the interconversion of alcohols and aldehydes, or ketones. Like other zinc-dependent alcohol dehydrogenases (ADH) of the medium chain alcohol dehydrogenase/reductase family (MDR), tetrameric ADHs have a catalytic zinc that resides between the catalytic and NAD(H)binding domains; however, they do not have and a structural zinc in a lobe of the catalytic domain. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit.	8.7448e-146
NZ_CP040605.1\|WP_168584170.1\|60399_61404_+\|3-oxoacyl-ACP-synthase	gnl\|CDD\|238426	cd00830, KAS_III, Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP. KASIII initiates this process by specifically using acetyl-CoA over acyl-CoA.	4.01406e-22
NZ_CP040605.1\|WP_168584072.1\|101159_112553_-\|hypothetical-protein	gnl\|CDD\|223039	PHA03307, PHA03307, transcriptional regulator ICP4; Provisional.	1.32537e-07

>NZ_CP040605.1|WP_168584173.1|71479_74416_-|hypothetical-protein
MAELARPFVGEGGDGWEGLAREVGLDVGRDDFREALKSLAELAWDVGFDGRKSAPVYVSRMKLLRVLIDAGFEDGRQGAAFYDRTVGDLRELVADLAEPVFNHVTGQREKPRPENVSDDEIRRWIEPMELVHYVGGYRKLVGEIGADLVSGRRLLRVVRVAYELYDENPDMATLRSLAWLASQLDPVSSNISLSSLAKMVARFERRDGGAFDSEVRDLVKLAGRARDVLGRLDSVQVDADADGDQQVRAEKALEAMWKADKRWRRVEGRLAGFAIPGPARDEQTVQWARGLAGFEDARAVVVREPAESQALLDAVVLTPFVTGIAEWFGGDWGAVAAEVGLGDVTNLPADYRESLLNLAALHWDTQPILLRNAVPVMRRLRLLIDAGLDDGREGAARYARTVDDLRALVAELPVFDPQTGRQLRLRSTRAVGDVEIYLWLDRMDVVHDLGGVGAVVGAVGADLVGGRRFFPVITLAQQLYGQNPDMATLRSLAWLASQLDPVSSNISWLYLAKMVARFEGRGGRAFPSEVRDLVSLAERARLVLGRLDSVQADADAYADGDQQVGPEKALEAMWKADKRWRRVEGRLATLAIPGPGRDEQTVRWARGLLAGFEDARAVVVREPAESQARLNAVVLTPFVTRIAEGFGGDWRAVAAEVGLGDVTNLPADYRESLLNLAALYWETEPILFDNAVPVMRRLRLLIDAGLSDGREGAARYARTVDELRSLVADLRVFELQAGRQQHLRSPGPVTGEEIRSWLWRMDLVHDLGGVGAVVGAVGADLVGGRRFLPVIALAQQLYNARRPGMATLRGLAWLASRLDPVSSNISPASLARMAADFEGREDWHGSLPEMHRLVELAGIAREDGGQVDGDPVQALKAMWNADKPWQRIGYKLAALAHPESRREEQTVQWARGLLIEFEEARSVVVREPAESQARLNAVVLTPFVTRIAEGFGGDWGAVAAEVGLGTYLICRLITGSPC
>NZ_CP040605.1|WP_168584172.1|62845_63493_-|amino-acid-adenylation-domain-containing-protein
MSTEWSRSADGNRVEPEEVEANLARNPSVRQVTALAPHDEQGQRYLLAFVVSVVGSRLSESDLRATAEVSLPDWMVPARFVLRDTLPVTDTGTRHLPQPTRPGRRVLGVLSTPGLVIEHGKRSGREQRADAAHPCAGPSPLHLRTRSGQGLHQRGGPGAGLAVEEGFDDGHSVPGNGIVQLPRLMLWWQRASILPPGPKPGNPSRGGTQPSARVS
>NZ_CP040605.1|WP_168584171.1|61747_61987_+|hypothetical-protein
MVDRFDTGGFAVRATPAPYPDALPGPEQIGSQVSVQNKDLSGCGPWHVRARPRFPLKLRRLSTGIGVSGSDTPTVRKFH
>NZ_CP040605.1|WP_168584170.1|60399_61404_+|3-oxoacyl-ACP-synthase
MTQTAGILGAGYSVPNGVRRNDDPAYASLNQNRNAQGVIEAAVFRGLDRRRVLAKGERIEDHVVKAADAALGKAGLEPADIDRLYGYITVPEYLTPNSLYHVHHLLGLPPEVMVVPINSEYSNFLLGVVHAAEAVEAGRTRNSLVACGANWTGHMDYTKGHAVSIGDAAGAAVVGPSDRFVVVDHLTQTASSQYHGLTMTMRTLHLNGLTLLPTDPVTGLPTPTYDMTQTGIEDLGGLVKDAVAVVALDLLKRNDVDPNQVTLMTHQGSRILMDHWNERIKPRDYLDTLAEHGNMTVATYPVNLAYYLDEITTEYTLIVAVACGLHVTALLLRN
>NZ_CP040605.1|WP_168589696.1|59335_60391_+|alcohol-dehydrogenase-catalytic-domain-containing-protein
MKALTLVAHNEVALAERPVPHPGPRDVVVRTTASMMCASDVHNLSGAMAVPVGRILGHESVGIVSRVGDAVTRVREGERVAVTSVTPCGCCDFCQSGAPQQCGGGVGGYKFTTQQDGSLAEYFVVPDADFNVARIPDELTDEQALYATDSMSTGLAAAEQANIPLGGTVAVFAQGAVGLSVTAGARLLGAGTVITTATRPLNARLSAQFGSDLVINPRHEDAINAIRDVVGQHGVDCAIEALGTHQTFEQAVRATKAGGTVVNAGYHGWQSTGHLPIPLVAFGFGMGGKTIRAMLCPGGSERLQRLFRLMVNKRIDPTPMTTHRFGFADAAKAFDLLASRADGIIKPLITY
>NZ_CP040605.1|WP_168584169.1|57225_59295_+|acetolactate-synthase-large-subunit
MTIPSPRHAGQITGAQALVQSLELIGAEVIFGLPGGAILPAYDALVDSKRLRHVLVRHEQCAGHAARGYAQATGNVGVCLVTSGPGATNLVTPLADAHRDSIPLVAITGQVPSTAIGTDAFQEIDVLGITLPITKHGFAVTNAEQIPAAIADAFRIARTGRPGPVVVDVCKDALLAATPFTKPRAPTPQAPAMCDEGLLRSALKLLRSASRPVLYVGGGAVLGEAAPELLRFAEHAGIPVVTTLMGLGVFPDSHPLHMGMPGMHGSVAAVGALQQADLLIAVGVRFDDRVTGQLSTFAPGAKVVHIDIDATEISRVRHADVPLVGDCKQVLGELHRLSAAEALRYDFTAWTSVLQRYQKTYRPAYEQPADGLSAPHVLRRLSELAAPDAVYVTGVGQHQMWTAQCIGFERPRSLITSGGLGTMGVAVPAAMGAKLALPEREVWAIDGDGCFQMTHQELATCVAERIPIKIAVINNGSYGMVRQWQNLFYDERYSHSELNAVGAAPDFVRLAEAYGCVGLRCTKADEIDEVVRDALEITDVPAVIDFQVPANELVWPMVGPGASNDDISIARGISPRWDTSTVREEVIARNASTELAGAPPRAVFVVARDTPYVVPRVTATVRRCGLTIDRMSLENHGGQQYLELSLGPSGVRGESLVDSLRDLADVLECKATVQEESDEYERLGHNAIG
>NZ_CP040605.1|WP_168584168.1|56547_56811_-|hypothetical-protein
MTIRTVSQPDGIGKAGLGWSRPLWWQDSAAVGGDVLRRTGDLGDVGQAKQAECGVAQSGKAWEPGSGVRVLVVFAVDGVAKPSAFCS
>NZ_CP040605.1|WP_168584167.1|55137_55755_+|response-regulator-transcription-factor
MDRVRVAVLAEDPITVAGLASCLKSREELFVAPNPAEADVIVFAADRVNAKVLAELRLSAQQVSAPRVLVTNEVNPADVLSVVESRVVAVLPRTSATGTRLTNSVVAAAKGAGTMPPDLLGELLKQVDHLQREVLTPRGLNASGLTNREVDVLRLMADGMDTAEIAQKLCYSERTVKNVIYGVTSRLNLRNRPHAVAYAMRAGAI
>NZ_CP040605.1|WP_168584166.1|54848_55043_+|hypothetical-protein
MEKVDLPEDAVSVLRQLETEMSEAREYVVRCRAAGNEEAAHLHDVWIDLLLEEWGRCRLFTQPT
>NZ_CP040605.1|WP_168584165.1|53734_54154_-|cold-shock-domain-containing-protein
MKTGTIVKYDGTRGFGFIEPDAGGEDVFLHASILDEQLKQVLQGGMRVQFEAASSNQGTKAVAVRLLGAVSQTPAPQILPVKQQERDDEELCEVLSAAEFSQKITDVLIEAAPSMTGGQILQVRSQLVAFAQRNGWVEA
>NZ_CP040605.1|WP_168584072.1|101159_112553_-|hypothetical-protein
MFSSIMVPEGVRRLFQVLTGEDMTDADEGVLFAVADALESGAAELGEVRALVAELVGKVRTEFSGKAADRFADGLGIFDGLLSSGQAGLLDLAAFVRKTSQQVRYLKLVTIYSLQLLWIEMAWAMQFAGATAGASLLWLAARMAVMRFLLTTWWGQLFMRLAMMAAGGVVFNVLPDVPAQLQMLGEESAEKWDRTLTEQAAGMGAFSALVALPLSAVGGLVSNMLTKVLVKGLGDDVDAAILEAAAKKAVAEHAELYPVSAMAKFADAVGKSLDDYAGMSVGTMWWARFGHSVGEAVENALSEFFGEAGYLAATGQEVTWNPFSLTAGLFETVFSGVGNLAGLALRGKLHPEGPSPYLEGTGGGGDGSDDGGGSGGEKTPLPGAGSGSQPGDIPGSPDKDSTFIPSDASQSDASDASQSDGWVGSGSGAGSDSSSVSDVDSVFSDTGSVDSAAVSVPSDDGLVVPASAVVSAVVVGGTDGKDGKDGTDGTDGKRGADGSVPGRDAAGDVPVAPGAGQHRPGTPPPAYSGGVPGVDPDRPGTPLPAHSGGVSGVGPDRPGTPPPPYSPVAGGDQAVPGKRPLEVSASKTPDSPTVIPHASDVPADPPRPETGRPGSVVESGSGVPAGHQVSETAGSRSVVGSGSGVPGDPSRPGTVGSGSAADAGSGVPAGHQGASGGVTGRDGDPGVDSVAGRRDAHRQDEAVVSPDSVTLPGEGAPAAPSLHRDPAAVLPAGLPADTVQVPVTAEVAAGGRLAEFVQGAAGSTGGPVLLVSDSDPNASVVVPSGQGSALAQEIRRNVVAMTPGQAGREPQLTVFPADGSPPKPLAGPGATVLAAGRSGGVAGLADASATVPAAGGKTVARGKAPAAGTTSAQQRSVAGEGQPTATTPDAGTGTVRDTSRIPVGQWTPSELASAIAEAKKLVLSSEEKDAARQIAWRAHDGAALARGDAVVPLEDVVALVAAKYHDLGDDHRDQVVEFSGALADLLRTRRSGPVIQAGAGPARLSGVEPAPVPFGELKPLKPPVDGRSEPRGGDAEDGRDGSRGSLPDVVDDQRGVLSADDLAGLSEEGRAALDAFQAATGVPAAPRLADVDGHNVLAYLRMWLDWLGVADRAVVVRKRKTTWRVHSWSSDLDGRELVEEGIDAWYVMGEYAPGARPDGAMRPEDLWGPLTEGAPDQATVPEHLDPNREFSSDDADLENIGESFEFFVHVVDPAGGRVEYGLADPGLWRRGREVEWGGLFAALQEEGPAELMDMVNPGVRESRYLAQVLGVDEATARVWRMWSHVPEGHAEALRRAIIGSTVSTYGGREEVKALVEDLVPAGARYQERLSALGQFMVGLADRRRLLGRSGAERRAQPGVPRSAAQYHAELRREVDRLGGLDRVVLEGPGPQRAGVSGRQPSRRELNVLRELVHALDGREFDYLPRFFGTDGLVTEAIGDDEWRRGGDRAVMRGVLLDTFLAAFGGPEGAVALADRLRELSLGPLKQLGLEMALQGELDPRRGMQVASQRLPDPQTAKTVLFLLMDDLLPWTLGDLVEFVAGGAVPAGVPDGELVSRLGTARAALATGVVESTAQRWLDGSQQPEPEYLQRMREAARLPSSELVRYLGPSRALEVTDTVWLGSDESGVWQWLMGFVEPRAGEAGKLRQGALRAIRDGLVPPAPSRRLGWSVSWILEAERRLAWADATKGGEFPSEAWEQWKKVKDSVRSLRPESRKVIDGLGESLRASVNYIVVQVLLGNEIAKAMVAGSGIVIPDPGPKAATELLEQIADSVRAADGMLHSGVLRRVVGGAASKEFQAATGGVVPQPRLTGGPDAVREFMEQWAGDDVHFLVLRMPPATPWRETSQDVPQAVYVNGNGPNTFPSGDFFEGGPAHYFLHAVRGDGRRIDPASTLSLGVMAAAGDALAWWAVPGRLRAPAADSDGDGSAAPVSQGEGSPPTAADVILGGPVQAWLDGRLPRVLHLTESVRRERLGNLAGLAEVAELAGWMEQHLKAMRPGFDPGGEHASNLEAAKRMLRKGAWTSTDLQTVADSLPGLREAEKAWKDLASRAREATGERKRRTSADPADPADSAGVKRRRLSWPGVVPGEATSASAAGGEPGGAGPERADPGGFGGPTPGRISSSPTRQPDPDPDAIETAPPLQPALVPAASGGTTVAGGEASATGTGSAQARSEAAGEEQPASTTPGAGAGTVRDTSEIPVGQWTQEDLVRAIAEAKKLDLSSDEKAKAAQIVRRAHDVVALARRDAVVPLEDVVALVAARYHDLGREHWAEVVEFSGELADLLRTRRSEPVIHAGAGPAQLSDVDSRRVPFGELKPLVEGGSELRGGEGSLPDVVDGRRVVLGAEDLAGVSGEGQAALEAFVEATGVAARPRLAGVDGHAEVDGHHVLASLEMLGWWGVVDRAVVVKKRTTTWRARKLLSDVDGRELVEEGVDVWYVMGENAPGRPDGANRPDDLWAPLTQGAPEVLRRVPPRLDPNGELPEGTSLENIGESVEFFVHVVDPAGVRVEYGLADQGLLRRGREVEWEGLFAALNDEGPAGLMGMVNPGVYRDLYLAQALGVDETTAWVWRMWSHLPEGWHAEALRRAIIGSVVSTYGGREEVKTLVEDLLPDGQRTKERLRALGELMMTLADRRRRLERWGEVTIDTPSADEYRDELRRKVDGLGGLDQVVLAASKPDSQVKRDLGGPARQSAGEPGRRPSPRELNVLHELAQTLDGDELGYLKRFLGDFWDIAYAVGVSAGDVQEWRRGRPSDRAVMRGIVLDTILAVFGGPEGAVAVEDRLRELTRLRRVRLFAHGQPERAATAADKVFGLPTTQGWWDWTLPGVVDYVAGAAVPADVSDEEVVRDLGAARAAKVTGVDDSTLQAWLDGSSQPLPFQQRLMREAARLPGSELVRYLGPGRALEVTDSGVVSEPVVWGWLTDVGEPSAELAGKLHQGALRAITDGVMQWPQPLRRVVWSESGIREAERRLAWADATKGDEFPSGALEQWQEVNNSLRSLRPEYREVIDGLGKSLRASVNYIVVQVLLGNAYARAMVEGSGIVIPAPGSEAAATELLEQIADHVRAAKGLLHSGVLRRVVGGAASAEFQGATGGVVPQLRLTGGRDAVRGFMEQSAGGGVHFLVLRVPLAASQDVPSATPQDVPSATPQDVPSATPQDVPSATPQDVPRAVYVKGDDATAFLASGDFFEDESAHYFVDAVQGDDRKIDPESVSSEVVAGAGDDVAWWAEHGGLGGPELVAWLDGRLPRVAGSLDAPESESVRLDRNLAGIAELAGIAELAKLAGWMQRHLTVMRPGFDPGGEHASNLEAAKRMLRKGAWTSTDLQTVADSLPGLREAEKAWKDLASRAREATGEGKRRTSADSADPADSAGVKRRRLSWPGVGPGEATSASAAGGEPGGAGQERADPGGFGGPVSGRISSSLTGQPGPDPAAIETAPSLQPALVPAASGGETVAGGEASATGTGSAQARSEAAGEGQPASTTPGAGAGTVRDTSRIPVGQWTQEDLVRAIAEAKELELDLSSDEKETAGQIVWIAHDVAALARGVAVVPLEDVVALVAARYHDLGREHWAEVVEFSGALADMLRTRRSEPVIQAGAGPARLSGVDSSRVPFGELKPLAPLTPSVEGGSEPRAGDAEYGRDGSRGSLPDVVDGRSVLGAGELAGVSEEGRAALEAFQAATGVPAEPRLADVDGHNVLAHLRMRLDWLGVADRAVVVRKWKTKWETRGRGQSSDPTVLVEEVIDAWNVMGEYASPGARPDSATRLEDLWGLLPPKVGQHNGGWCRRIWIRTGFCRRVPGW
>NZ_CP040605.1|WP_168584073.1|112739_112985_+|hypothetical-protein
MQALADPPGVGTAETVRRWVRHSETDTAARAGVASEKSAESQRLRRENTEVKRDNAILKRDNAILTAASAFFATEIAPPHR
>NZ_CP040605.1|WP_168584174.1|114077_114575_+|AAA-family-ATPase
MILIRPPGAGKGTQAHTLATQLGVAHISTGDLFRRHVGSRTVLGERLKRSWSGGELVADEITLETVRDCLTKATPPVTSWSTTSPAPSSWPCSCNSSSGNREPTIDAVLEMHVGEDEIVRHLGRRTCRECGRSWHVEFNPPHVEGSCDACGSALARDQRCRHSRP
>NZ_CP040605.1|WP_168584175.1|116257_116455_+|hypothetical-protein
MNAGLPHSRPRSAGAAATVVALARLVTVVRYHHLDAEIRTQVRGGFIVLCGRCVALSWVHAGAKN
>NZ_CP040605.1|WP_168584176.1|116539_116995_-|SsgA-family-sporulation/cell-division-regulator
MVRNHRLIIRFGTIFDLATPPVASTPIQLELRYDTRDPYAVGMIFNPGRNSRAHWMIARDLLSAGLVSRSGEGNVRISPRPDNPELVVIALTTPSVQGVFETRADVLARFLNDTYAVIASGDEHRWLSVDDVLSKVLLNDQRNDRSPAEHD
>NZ_CP040605.1|WP_168584177.1|117579_117723_-|hypothetical-protein
MTDRAYRIPMSGVTGRMGYRLAQALSMKCGIGTAARHRATRSAPQRQ
>NZ_CP040605.1|WP_168589697.1|118002_118641_+|TetR-family-transcriptional-regulator
MAATAAQVTSHARRLTAERGLSGFTVEEVCEQVDISRRTFFNYFASKDDAVLGVPARGNDDDALKAGFVASGDPTSGDPTSGDPANTGLSPTLLDDLAELAVQRWERSDITAESIREVLTAFEREPRLFTRIIEKLLRDEQSDVELVEQREGLAAGDLRAGAAVQLIRTLARATAREFLTRTNTDTFAEILARRLAAARALFAPNPDPERKS
>NZ_CP040605.1|WP_168584178.1|119131_119530_+|IS200/IS605-family-transposase
MAVTLRSNANITFQCAFHVVWCPKYRRRVIGGRMEERLKQLIREVVEEKGAWLVELETMPDHVHLLVEVDPQYGVHKLVKAIKGRSSRVLREEFPWLRSKLPTLWTNSYFVATVGGAPLSVIKRYVEQQKAR
>NZ_CP040605.1|WP_168584179.1|119534_120752_+|transposase
MLTGRRYRLKLTTAQAAQCEEFGNICRAVWNTALEQRREYRRRGAWMNYNEQAGQLADAKTEHDWLQTVPSHILQQALKDLDRACRDHGTFRVKWRGKQRWNPSLRFPMGKLIEVERLNKRWGRAKLPKLGWVQFRMTRQLGGAVRSATVSRDGQDWFVSFLVDDGAITPERHAAPHSGVGVDRGVAAAVATSDGKLIDRDFVSPGEDERYRGLQQKLSRQKRGSANRKKTLGKMRRLKRRERDRRADFCSQVAAELTDRNALVVLEDLRTRNMTRSASGTAGEPGRNVAQKSGLNRAILDKGWHKLELALGNAARYTGSEIVKVPAAYTSQTCAVCRAVDPESRESQAVFRCTQCGHTAHADVNAAKNILAAGRAVTACGDLAVRRSVKQEPQPALALVGIPRL
>NZ_CP040605.1|WP_168584180.1|121738_123898_-|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit
MTSRLDGPLKVTGQAKYGADNNFPGMVYGYVVLSTIAHGEIEAMDVTAAKSAPGVLGVYTPFDPLELRKPSSPVFGETWVPLQDREVTYYGQPIGFVVAGTFEQARDAALLIEVTYHARPALTSLQDGLASAEPAPSNEDITVLADDVESIEDALGASPVVVEATYRTATQNHAAMEPHSAVAVWDSAGLTVYSGNQGSDLQAGELAAALGLEGSSVRALNPFVGGAFGGKARTSAPAFLAAAAAKALGRPVKAALTREQVFTATATRAATVQKISLGADAGGTLIALRHDSWCSTPADRSFVEPTSHGTSREWYATQNLSISQKIVPLNIPPTTFMRAPGEAPGSFALESAIDELAVALNMDPIELRLRNNSLAPPGNDLQWSSKHLDECFQVGAQRFGWANRSPRGRADGDWLVGMGVATAMFPALRFPATVEITLREDDTAVVATSGADPGTGLLTVLALVGAESLAIPADRITPKLGDSALPSGGMSGGSTGTASAGSAVMIAATEVIDALLALTSSPGAPFEGAELSYEDGRVLADDGRAMTFGEVLRALGRSSISATGSSAPGEELAKHSFSSFGAQFCEVRVHKWTRETRLSRMLGVFDCGRIINEKAARSQAIGGMIWGVSAALHEALEIEESGRLANADFAGYLVPVNADIPDVDVHFVKYPDTLHNAVGAKGLGEIGTVGMAAAVANAVYHATGIRVRHIPITIEDLLD

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Crispr_ID: NZ_CP040605_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_3

460892-461035

Orphan

Consensus_repeat	Method
TCGACCTCGCCCCGCTGCGC	PILER-CR

2 spacers

WYL

The CRISPR arrays of NZ_CP040605_3

>merge|NZ_CP040605|3|460892-461035|PILER-CR
GACCTCTCCCCGCTGCGCTCCGCGCCGGTGGAGGTGCTGACCGCCGACCTGGACCGCATCGACCTCGCCCCGCTGGCCGAACACCCGACGCTGCGGCTGCTGAAGCTGGCCACCGGCGAACCGGTCGACCTCGCCCCGCTGCGC

>NZ_CP040605|3|1|460892-461035|PILER-CR
GACCTCTCCCCGCTGCGCTC	CGCGCCGGTGGAGGTGCTGACCGCCGACCTGGACCGCATC
GACCTCGCCCCGCTGGCCGA	ACACCCGACGCTGCGGCTGCTGAAGCTGGCCACCGGCGAACCGGTCGAC
CTCGCCCCGCTGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168589727.1\|448738_449656_+\|5'-3'-exonuclease	unknown	unknown	gnl\|CDD\|214682
NZ_CP040605.1\|WP_168584441.1\|472405_472942_+\|DUF3558-domain-containing-protein	unknown	unknown	gnl\|CDD\|378803
NZ_CP040605.1\|WP_168584434.1\|458375_459371_-\|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NZ_CP040605.1\|WP_168584440.1\|471995_472409_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168584432.1\|457188_457389_-\|bacteriophage-holin	unknown	unknown	unknown
NZ_CP040605.1\|WP_168584429.1\|451961_452543_-\|DUF4333-domain-containing-protein	unknown	unknown	gnl\|CDD\|379513
NZ_CP040605.1\|WP_168584439.1\|465249_466365_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168584442.1\|473236_473527_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168584444.1\|473954_474812_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379262
NZ_CP040605.1\|WP_168584436.1\|461376_462735_-\|Pup--protein-ligase	unknown	unknown	gnl\|CDD\|274725
NZ_CP040605.1\|WP_168584438.1\|464728_465253_+\|DUF4365-domain-containing-protein	unknown	unknown	gnl\|CDD\|379535
NZ_CP040605.1\|WP_168589729.1\|466336_468127_-\|DUF1998-domain-containing-protein	unknown	unknown	gnl\|CDD\|378167
NZ_CP040605.1\|WP_168584433.1\|457407_458379_-\|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NZ_CP040605.1\|WP_168589728.1\|455860_456802_-\|twin-arginine-translocase-subunit-TatC	unknown	unknown	gnl\|CDD\|376413
NZ_CP040605.1\|WP_168584428.1\|450721_451918_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|234945
NZ_CP040605.1\|WP_168584430.1\|452640_455418_-\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|226947
NZ_CP040605.1\|WP_168584443.1\|473570_473783_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168584427.1\|449669_450512_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293828
NZ_CP040605.1\|WP_168584431.1\|456837_457110_-\|Sec-independent-protein-translocase-subunit-TatA	unknown	unknown	gnl\|CDD\|234797
NZ_CP040605.1\|WP_168584437.1\|462929_464408_+\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|224513

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168589727.1\|448738_449656_+\|5'-3'-exonuclease	gnl\|CDD\|214682	smart00475, 53EXOc, 5'-3' exonuclease.	8.41897e-80
NZ_CP040605.1\|WP_168584434.1\|458375_459371_-\|WYL-domain-containing-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	3.17516e-36
NZ_CP040605.1\|WP_168589728.1\|455860_456802_-\|twin-arginine-translocase-subunit-TatC	gnl\|CDD\|376413	pfam00902, TatC, Sec-independent protein translocase protein (TatC). The bacterial Tat system has a remarkable ability to transport folded proteins even enzyme complexes across the cytoplasmic membrane. It is structurally and mechanistically similar to the Delta pH-driven thylakoidal protein import pathway. A functional Tat system or Delta pH-dependent pathway requires three integral membrane proteins: TatA/Tha4, TatB/Hcf106 and TatC/cpTatC. The TatC protein is essential for the function of both pathways. It might be involved in twin-arginine signal peptide recognition, protein translocation and proton translocation. Sequence analysis predicts that TatC contains six transmembrane helices (TMHs), and experimental data confirmed that N- and C-termini of TatC or cpTatC are exposed to the cytoplasmic or stromal face of the membrane. The cytoplasmic N-terminus and the first cytoplasmic loop region of the Escherichia coli TatC protein are essential for protein export. At least two TatC molecules co-exist within each Tat translocon.	1.26342e-68
NZ_CP040605.1\|WP_168584438.1\|464728_465253_+\|DUF4365-domain-containing-protein	gnl\|CDD\|379535	pfam14280, DUF4365, Domain of unknown function (DUF4365). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, eukaryotes and viruses. Proteins in this family are typically between 182 and 530 amino acids in length. There is a single completely conserved residue D that may be functionally important.	3.82922e-17
NZ_CP040605.1\|WP_168584429.1\|451961_452543_-\|DUF4333-domain-containing-protein	gnl\|CDD\|379513	pfam14230, DUF4333, Domain of unknown function (DUF4333). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 140 and 255 amino acids in length. There are two completely conserved C residues that may be functionally important.	5.07189e-24
NZ_CP040605.1\|WP_168584444.1\|473954_474812_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	1.20602e-08
NZ_CP040605.1\|WP_168584436.1\|461376_462735_-\|Pup--protein-ligase	gnl\|CDD\|274725	TIGR03686, pupylate_PafA, Pup--protein ligase. Members of this family are the Pup--protein ligase PafA (proteasome accessory factor A), a protein shown to regulate steady-state levels of certain proteasome targets in Mycobacterium tuberculosis. Iyer, et al (2008) first suggested that PafA is the ligase for Pup, a ubiquitin analog attached to an epsilon-amino group of a Lys side-chain to direct the target to the proteasome. [Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_CP040605.1\|WP_168589729.1\|466336_468127_-\|DUF1998-domain-containing-protein	gnl\|CDD\|378167	pfam09369, DUF1998, Domain of unknown function (DUF1998). This family of proteins are functionally uncharacterized. They are mainly found in helicase proteins so could be RNA binding. This family includes a probable zinc binding motif at its C-terminus.	1.85025e-12
NZ_CP040605.1\|WP_168584433.1\|457407_458379_-\|WYL-domain-containing-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	1.33092e-43
NZ_CP040605.1\|WP_168584437.1\|462929_464408_+\|phosphatase-PAP2-family-protein	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	7.34964e-22
NZ_CP040605.1\|WP_168584428.1\|450721_451918_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|234945	PRK01346, PRK01346, enhanced intracellular survival protein Eis.	7.57578e-118
NZ_CP040605.1\|WP_168584430.1\|452640_455418_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|226947	COG4581, COG4581, Superfamily II RNA helicase [DNA replication, recombination, and repair].	0
NZ_CP040605.1\|WP_168584427.1\|449669_450512_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293828	cd07742, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	4.35788e-118
NZ_CP040605.1\|WP_168584431.1\|456837_457110_-\|Sec-independent-protein-translocase-subunit-TatA	gnl\|CDD\|234797	PRK00575, tatA, Sec-independent protein translocase subunit TatA.	1.48001e-19
NZ_CP040605.1\|WP_168584441.1\|472405_472942_+\|DUF3558-domain-containing-protein	gnl\|CDD\|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	4.53037e-14

>NZ_CP040605.1|WP_168584434.1|458375_459371_-|WYL-domain-containing-protein
MATVRAERLVNLVLCLLSTRQYLTAERIRAIVPGYAGAPTGEAFFRTFERDKAELRDLGIPLETGRNSAFDSADGYRIARRDYELGDIDLEPDEAAAVALAVRLWDSPEFTSAARGALLKLRAAGVDVDERSSAAVEPKVRTSEPAFASLLAAVQAGRVVEFDYRRPSSPDVHRRTVEPWGVVSWRGRWYLVGHDRDRQAPRCFRLSRILGQAKTVGPAGQVQRPPDTDLLRLVAGEQREPPPSTLARMWVAAGRAQGLRRRATVVEQMELGGDPGDVLELDLLFPESAASWLAGYGPDVAVLEPDTLRKTVHEIHLDVVDQERGFDQEGR
>NZ_CP040605.1|WP_168584433.1|457407_458379_-|WYL-domain-containing-protein
MTSATARLPRLLALVPYLLSRPGIPIADAAGDFGVTEQQLRKDLELLWMCGLPGYGPGDLIDLSFESDSITVTYDAGMRRPLRLTASEATALLVALRALADTPGIADTDAVQRTLAKVEDAVGQARPAGVVVGLEGREGAVRPGVRSAVQDATTRRRALRMRYYTASRDDISERIVDPMRLLLIDGRSYLEAWCRSAAGVRMFRLDRIDDVQVLDEVAQPPSEAEPTDLSAGLFRPAPDQLVAELELEPDARWVAEYYPVDELVELPRGRARVRMRYSDRSWMARLLLGLGGQVRVLSPDELACDVRQRAKDALARARHLPST
>NZ_CP040605.1|WP_168584432.1|457188_457389_-|bacteriophage-holin
MPYTWSLVLLAAGLILLALLLIRLFRELRRFKAVQRQVFHDFGDRSGLVKARVAGLKVAFAQRRDR
>NZ_CP040605.1|WP_168584431.1|456837_457110_-|Sec-independent-protein-translocase-subunit-TatA
MGLPGGWELILIVLVLVLLFGATKLPQMARSLGQSARVFKAEARGMKADEEAAKKEKAEREPKPELTSGESGAPPVTSALDEKQRNDSKN
>NZ_CP040605.1|WP_168589728.1|455860_456802_-|twin-arginine-translocase-subunit-TatC
MGRLNPFRKDRRRWGRRHNPDGTMTLVDHLYELRYRLGVAIVAVVVGAIFGIWWFSNSVFGLPTLSDVLLEPYCQLPVTQRLSPNGTCQLLQTEPFEIFMLTLKVGVSIGAVLFSPVWLYQLWAFITPGLYAKERKFARLFVSCATVLFVAGAVLAYYILPTALGFMSGFGGNAFFTALTGGKYISFMLLLLVIFGVSFELPLILVMLNLAGIVSYAKLKSWWRGLVFALFVFAAIATPGQDPFSMLALAAALSVLFAIAMLICRVNDKRRARKLEGQGLEGLSPDEASKIDFRASGLDSTPSPSPKQHDDVT
>NZ_CP040605.1|WP_168584430.1|452640_455418_-|DEAD/DEAH-box-helicase
MAASRSYPTKPSPADAFSAHARRSAHPKLAEFAGELSFELDPFQRTACQALEAGHGVLVCAPTGAGKTVVGEFAVHLALKEGRKCFYTTPIKALSNQKYADLCERHGSDAVGLLTGDTSINGEAQVVVMTTEVLRNMLYAGSRSLDQLGYVVMDEVHYLADRFRGAVWEEVILHLPEYVQVASLSATVSNAEEFGEWLQEVRGDTTVVVDEHRPVPLWQHMLVGPRMFDLFGGETADRELQINPNLVRHTQQLARVHLPYGGRRGGPNTRGKGPRPPRFYPPSRVETLTGLDAAGLLPAIVFIFSRNGCDQAVSQCMRAGLRLTTDAEIDEIREVIDEHTANLPESDLAVLGFWEWREALERGLAAHHAGLLPAFKETVEELFVRGLVKAVFATETLALGINMPARTVVLERLVKFNGESHVDLSPGEYTQLTGRAGRRGIDVEGHAVVVWQPGVDPKQVAGLASTRTYPLRSSFRPGYNMAVNLVQRVGQDAARELLEQSFAQFQADRSVVGLSRRVDRNNEALTGYSEAMHCHLGDFDEYFELRRRISEREKHLARQNRQSRRAEAAKSLEKLRKGDVIAVPGGRRSGLAVVIDPGLEPMGEPRPLVVTEDRWSGRLSVADFTSPVEPLGKIKLPKHVDTRSPKSRRDLASTLRNTGLEAPGGRGRRRSDATDDAELATLRRALKAHPCHGCDERESHARWAERYERLRGENENLRRKVAATTHSLARSFDRIVALLTERDYLPVAGSSEGEVTQHGRRLSRLYSESDLLAAECLRVEAWRGLGPAELAAVVSSLVYESRREGLAPQVPAGAVSDALAATWRLWAELEDDERRHKLDRTREPDAGFAWPVFRWARGESLEKVLTAAASSGHELSAGDFVRWCRQVIDLLDQIREVVGAADPVGSSAVKAVTAIRRGVVAAGAL
>NZ_CP040605.1|WP_168584429.1|451961_452543_-|DUF4333-domain-containing-protein
MSSPYGPPGGYPQWGQQPQGPGMQPAAPGYPQPGGFAPQRPPQQPPQQPQPPQQQPYGYGRPQYPQGGQYPAPGGYGRFDQFERPKKKRSALPWVLGGIGAVLVVGVVLVLGFVTPGWFVRPVFDAASVEKGVTQTLKGSYGLQGVGNVSCPSGQPVAVGQRFDCKVSIDSATKTVTVTVKNEKGVYEVGHPK
>NZ_CP040605.1|WP_168584428.1|450721_451918_-|GNAT-family-N-acetyltransferase
MSQHEVRALSESEFRGANDLFRHALLWQPSSDEEWAGNAALHEPGRVLGAFVDGELAGTTRTITNMLAVPGGRRLPAGAVAGVGVRADQTRRGVLTSLMRAQLEEVRERGEAVAMLRASEAVIYERFGYGVATRCRSVELDRARVAVRAEMPRGGRVRLVDQAKAEPLLPAIYERCGLDRPGRIGRADAWWSAQWSMLGKGLTVAVHADEDGVDDGFLIYEPKTDDNRFNTVRVVDVSAADATATAELWRFLFDLDLGDRLVAGIRPVDEPLEWWLTDRRQCRITTVEDDLWVRLVDVLAALRARTFGAADPVVVEVRDAFLPENEGRYRVGPDGVDRCSGEPQLSLDVATLAALYLGDQSASALVAAGRVQAHDPAAVPAADSLFATVVPPWCGTSF
>NZ_CP040605.1|WP_168584427.1|449669_450512_-|MBL-fold-metallo-hydrolase
MRVHHLNCGTMRPFGGRLVNEGGGLLGPARMVCHCLLVETERGLVLVDSGLGVPDVTTHVEHLERSWLRLTRPVLDVAETAAAQIKRLGYRTEDVQHIVLTHLDRDHAGGLPDFPQAQVHVHDVEYQAMLRSPEPSRYLGHQWRHGPKWNVHGSSGGERWFGFEAVRDVPGLPPEILLVPLVGHTRGHAGVAVRRPDGRWLLHAGDAYFYHGEMADSPHCTPVLRHFQNRAQEDGPQRRRNQDRLRDLVTAHRSEIDVFCAHDPVEFERHLRAESTVDRC
>NZ_CP040605.1|WP_168589727.1|448738_449656_+|5'-3'-exonuclease
MLVDSAGLWFRSYYALPDSLTAPDGTPVNSVRGFCDMLAKLISDRRPSRLVACLDNDWRPQFRVDALPSYKAHRVAEDDPAAEEVPDTLSPQIPVILEVLDAAGIATAEAEGYEADDVIGALADREDRDPVEVVTGDRDLFQLVRTQPTAVRVIYVGAGLAKAQDYGPAELAEKYALSADRAGDDYAEMAMLRGDPSDGLPGVAGIGEKTAAKLIIQFGSLEALLAAAGSGDSRLTPRIRGKLAEAADYLAAAPSVVRVARDAPVVQDRPDALPQSPVDIDRLRELQRIWGLGASIDRLIAALTP
>NZ_CP040605.1|WP_168584436.1|461376_462735_-|Pup--protein-ligase
MQRRIFGIETEFGVTCTFHGQRRLSPDEVARYLFRRVVSWGRSSNVFLRNGARLYLDVGSHPEYATAECDDLVQLVTHDKSGERILEDLLIDAERRLSDEGIGGDIFLFKNNTDSAGNSYGCHENYLVGRSGEFSRIADVLLPFLVTRQLICGAGKVLQTPRGAVYCLSQRAEHIWEGVSSATTRSRPIINTRDEPHADAERYRRLHVIVGDSNMSEVTTLLKVGSANLVLEMIEQGVQFRDFSLDNPIRAIREISHDLTGRRTVRLAGGREASALDIQREYFGRAVDHVARRGSDPMTERILELWGRALDAIEQQDFSLIDREIDWAIKHRLLERYRGRHGLELSSPRIAQLDLAYHDIRRGRGLFDMLQRKDLVDRATEDGEIEAAKDTPPQSTRAKLRGDFIAAAQAAGRDFTVDWVHLKLNDQAQRTVLCKDPFRAVDERVERLISSL
>NZ_CP040605.1|WP_168584437.1|462929_464408_+|phosphatase-PAP2-family-protein
MRGRLRHTINAVDGELARRSARLPASVADRRLKTLSTAANHSVLWLSIAAVLACRKGAPRRAALRGVVAIAGASATTNLIGKPLFPRRRPAAELMSQHRRLNDPPTSSSFPSGHAASAAAFATAAAMESPVTGAAIAPVAAAVAYSRVHTGVHWPTDVVCGAALGAGVAWATRRWWPVRPDTPAAGSHPAGLPALEDGDGMLALVNPGSGNGQPAPEQWVGEQWPKAVVVHPGPDADLVDGLREQLARGGDSVRALGVAGGDGTVAAVATVASEHGLPLAVVSAGTLNHFARDIGVGDPAAVAESVSTGSGATVDLGAVAIDDVPACRFVNTASLGGYPDMVRFREKWEPRWGKWPAAAMALIRVLHESRPLDVQIDGERHRVWVLFVGNGTYAPRGFAPAWRPGLDNGTLDVRMVRADRRFSRLRFALAAMTGALHRSRTYVERQVSRMDVVVRGTPVALATDGEVHRPGRRFSFTTHENALNIYRPNTVD
>NZ_CP040605.1|WP_168584438.1|464728_465253_+|DUF4365-domain-containing-protein
MSMALDPNQHQGVFGEAFVAVLATAAGLTVSRPYPDVTGEDFTLGHKGRLVGRRHPKIDVQVKSWSRSQATWRDGVWKYRMQANHFNDLADSALPLRRYLFLVIVPADATQYAVGGEGQLILSHAAYWVHLQGRDLVDPSVQATVSVDVPATNLLTVDSLRDLIEGKDDEEVRR
>NZ_CP040605.1|WP_168584439.1|465249_466365_+|hypothetical-protein
MTSYPDADLLVAVKPEDIATYLRASGWYEADHYNQATIWTHGPAGNETDVLAPPNNTFRDYPRRMIELLATVADVEQREPADVLQDLLSVQVDVQYIRTMPDSPSGTTPLHHGYQAVKGVHDLFLSAAASAHLPEPMAVLPSQKPPEAWDFIGGVRLGQTAPGSYIFRVETPLTGAGSPAGSPSRRVLDHLHLAMNSAHRAAADTDLPDGSRPFAEHIASGVSANLCEALSSIGALGNSAFEIKFAWAATLPMERPTPDLHFDTESISRIKKAGQYLRDLPAHREAQIEGRVVELRSYRPDKQGVVVIAGVLTTPQGRSTERVLVVLPNRYYELAHESHPGRKRVRAVGLVKTSGRQPELSAVTEFEVLED
>NZ_CP040605.1|WP_168589729.1|466336_468127_-|DUF1998-domain-containing-protein
MADLPNLSVVMLGLDYWNLERSRTVPEERLLAAVRAKLGNQVDTLRLPPYLPETWDPFAEWTRVGVPVGLFPGWLRCTNCGRLGRVGDGLFYRLDNVVRPEQTRFVHDCRGKGYGRPVAVPARFVLACEDGHLDDFPWLYFVHRGGEPGPGHSLKMSETGSTGEAADVFVTCDQDGCASRPMSEAFGEAAEQNLPACRGRHPHLGTFSECARQTRTLVLGATNSWFPMQLRAITLPRAKNPIDHLVAEYAEQLQLLAALDAATAKRLMPTQTCWPQLEPYGPDAVWQALKRHADTDGSAEDAVEDLRTPEWKAFTDAETVNLPDFTTKHEGVPQTARKWLDRVVLVPRLREVAALYGFTRIDAPEWDVQDTPSDRSAPLSSADPSWVPCAEMRGEGIFLRFNEERVATWERNSEALKRERTVLIPAFKKWCQQRRLPDNDWPGLRYVLLHTVAHVLIRELALESGYSAAGIGERIYATDGPAPMAGILLYTAAPDSEGTLGGLVSLGSKERLGQLIERALDAATRCSSDPLCSEHDPTTHGRLHGAACHACLFASETSCERGNHFLDRALLVDTLAHSGLAFFTGAAVSPRAPRTR
>NZ_CP040605.1|WP_168584440.1|471995_472409_+|hypothetical-protein
MTEAADIAFTGAQEGLRAIAAQTQWINQQVGAGKLTLDPEAAEKAAKRCEDESNGLRTLFDEARAIARVEGLGNYPDGQQLAKRFEDKANDPQAGAFALIRQMQAELKKQADAFRAAARDYRATDEQNADDLRRGMQ
>NZ_CP040605.1|WP_168584441.1|472405_472942_+|DUF3558-domain-containing-protein
MSVFSRSLIAGAAGLALVGLAACSNGNRSDGDTQKTSTSPAPERALASFDPCTFFKADELTSWGLPTQSETFSPLSFEPGCRWEGKEMSLTLQKNADETVASYRENGSWDFYNDKTFGGRTGALAAEAGVSGTGGCTVLVDAGGGVAIYMVSGAMQDSVDACAEAEKIANQTASRFPK
>NZ_CP040605.1|WP_168584442.1|473236_473527_-|hypothetical-protein
MFWLQLSTLVLINLLIVALIASSSTLRSPLFTRVQYVGADEGAYNVWDLIAQVEAERDAEREAEQDCLVERPYRPEPPRFPQFDPDEPTGRHHLRP
>NZ_CP040605.1|WP_168584443.1|473570_473783_-|hypothetical-protein
MNEYLTYIWRPVAGGRHAFPIAAKKTPAGERVAAYCGAEADSAELHDRTEVDWIREDSCMKCWRIIADRN
>NZ_CP040605.1|WP_168584444.1|473954_474812_+|helix-turn-helix-domain-containing-protein
MEERVSPTVRLRKLTRGIRRWRAEAGLRQDDVVAALDWSKAKLSRFENAEKGAGPAEVIALATVYGVPEAERDQYVALALQARQKGWWQRYGQDTLASNFEEYVGLESEATEVREFAAELIPGLLQTECYATELIRAWIPTADEVVMKERADLRAQRQARLREADPLTLRTVIHESALRQLVGGPEVMREQLRHLVTSAKLPNVAVQVLPFSAGAIPALGAPFILLSFPDHDDPDVAYADYLTGCLYLEDPTEVETYNLNYSALRAKALSQKESIAFLNRLAREL

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Crispr_ID: NZ_CP040605_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_4

583687-583830

Orphan

Consensus_repeat	Method
CAATTTCAATGGAAATTGCGGACCT	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP040605_4

>merge|NZ_CP040605|4|583687-583830|CRISPRCasFinder
CAATTTCCATTGAAATCGAAGGTCCAATTTCCATTGAAATCGAAGGTCCAATTTCAATGGAAATTGCGGACCTTCGGCGTGTCGAGCCACGACACGCCGAAGGGTGTGGACAACTTCCGCAATTTCAATGGAAATTGCGGACCT

>NZ_CP040605|4|3|583687-583830|CRISPRCasFinder
CAATTTCCATTGAAATCGAAGGTCC	AATTTCCATTGAAATCGAAGGTC
CAATTTCAATGGAAATTGCGGACCT	TCGGCGTGTCGAGCCACGACACGCCGAAGGGTGTGGACAACTTCCG
CAATTTCAATGGAAATTGCGGACCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168584525.1\|586319_586766_-\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|371225
NZ_CP040605.1\|WP_168584518.1\|573657_574644_-\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NZ_CP040605.1\|WP_168584520.1\|578965_580045_-\|DUF2961-domain-containing-protein	unknown	unknown	gnl\|CDD\|378582
NZ_CP040605.1\|WP_168584530.1\|590323_591004_-\|ribulose-phosphate-3-epimerase	unknown	unknown	gnl\|CDD\|235515
NZ_CP040605.1\|WP_168584528.1\|588554_589202_-\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|236455
NZ_CP040605.1\|WP_168589743.1\|584634_584925_-\|branched-chain-amino-acid-aminotransferase	unknown	unknown	gnl\|CDD\|235841
NZ_CP040605.1\|WP_168589742.1\|580551_581568_-\|dihydroorotate-dehydrogenase	unknown	unknown	gnl\|CDD\|240091
NZ_CP040605.1\|WP_168584517.1\|572310_573321_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|223135
NZ_CP040605.1\|WP_010310747.1\|575599_576478_-\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|235450
NZ_CP040605.1\|WP_168589741.1\|574634_575591_-\|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK	unknown	unknown	gnl\|CDD\|211689
NZ_CP040605.1\|WP_168584521.1\|581709_582465_+\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
NZ_CP040605.1\|WP_168584523.1\|584096_584465_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168584522.1\|582457_583615_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340951
NZ_CP040605.1\|WP_168584519.1\|576470_578513_-\|excinuclease-ABC-subunit-UvrC	unknown	unknown	gnl\|CDD\|234792
NZ_CP040605.1\|WP_168584524.1\|585030_585405_+\|FKBP-type-peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl\|CDD\|223619
NZ_CP040605.1\|WP_168584075.1\|585521_585680_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168584526.1\|586762_587260_-\|6,7-dimethyl-8-ribityllumazine-synthase	unknown	unknown	gnl\|CDD\|234606
NZ_CP040605.1\|WP_168584516.1\|570771_571989_-\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
NZ_CP040605.1\|WP_168584527.1\|587256_588555_-\|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase/GTP-cyclohydrolase-II	unknown	unknown	gnl\|CDD\|181774
NZ_CP040605.1\|WP_168584529.1\|589225_590248_-\|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD	unknown	unknown	gnl\|CDD\|273015

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168584525.1\|586319_586766_-\|PH-domain-containing-protein	gnl\|CDD\|371225	pfam10756, bPH_6, Bacterial PH domain. This domain has a bacterial type PH domain structure. This domain was previously known as DUF2581. This family is conserved in the Actinomycetales. Although several members are annotated as RbiX homologs, RbiX being a putative regulator of riboflavin biosynthesis, the function could not be confirmed.	1.70809e-16
NZ_CP040605.1\|WP_168584518.1\|573657_574644_-\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	1.41386e-126
NZ_CP040605.1\|WP_168584520.1\|578965_580045_-\|DUF2961-domain-containing-protein	gnl\|CDD\|378582	pfam11175, DUF2961, Protein of unknown function (DUF2961). This family of proteins has no known function.	3.99774e-115
NZ_CP040605.1\|WP_168584528.1\|588554_589202_-\|riboflavin-synthase	gnl\|CDD\|236455	PRK09289, PRK09289, riboflavin synthase.	1.32896e-102
NZ_CP040605.1\|WP_168589743.1\|584634_584925_-\|branched-chain-amino-acid-aminotransferase	gnl\|CDD\|235841	PRK06606, PRK06606, branched-chain amino acid transaminase.	1.58696e-40
NZ_CP040605.1\|WP_168589742.1\|580551_581568_-\|dihydroorotate-dehydrogenase	gnl\|CDD\|240091	cd04740, DHOD_1B_like, Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires FMN as co-factor. DHOD divides into class 1 and class 2 based on their amino acid sequences and cellular location. Members of class 1 are cytosolic enzymes and multimers while class 2 enzymes are membrane associated and monomeric. The class 1 enzymes can be further divided into subtypes 1A and 1B which are homodimers and heterotetrameric proteins, respectively.	2.12116e-72
NZ_CP040605.1\|WP_168584517.1\|572310_573321_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|223135	COG0057, GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism].	0
NZ_CP040605.1\|WP_168584530.1\|590323_591004_-\|ribulose-phosphate-3-epimerase	gnl\|CDD\|235515	PRK05581, PRK05581, ribulose-phosphate 3-epimerase; Validated.	1.87556e-126
NZ_CP040605.1\|WP_168589741.1\|574634_575591_-\|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	1.17857e-100
NZ_CP040605.1\|WP_168584521.1\|581709_582465_+\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	5.49811e-70
NZ_CP040605.1\|WP_010310747.1\|575599_576478_-\|RNase-adapter-RapZ	gnl\|CDD\|235450	PRK05416, PRK05416, RNase adapter RapZ.	1.39528e-162
NZ_CP040605.1\|WP_168584522.1\|582457_583615_+\|MFS-transporter	gnl\|CDD\|340951	cd17393, MFS_MosC_like, Membrane protein MosC and similar proteins of the Major Facilitator Superfamily of transporters. The gene encoding Sinorhizobium meliloti membrane protein MosC is part of the mos locus, which encodes the biosynthesis of the rhizopine 3-O-methyl-scyllo-inosamine. MosC belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.0548e-93
NZ_CP040605.1\|WP_168584519.1\|576470_578513_-\|excinuclease-ABC-subunit-UvrC	gnl\|CDD\|234792	PRK00558, uvrC, excinuclease ABC subunit UvrC.	0
NZ_CP040605.1\|WP_168584524.1\|585030_585405_+\|FKBP-type-peptidyl-prolyl-cis-trans-isomerase	gnl\|CDD\|223619	COG0545, FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones].	4.30567e-38
NZ_CP040605.1\|WP_168584526.1\|586762_587260_-\|6,7-dimethyl-8-ribityllumazine-synthase	gnl\|CDD\|234606	PRK00061, ribH, 6,7-dimethyl-8-ribityllumazine synthase; Provisional.	8.98586e-63
NZ_CP040605.1\|WP_168584516.1\|570771_571989_-\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NZ_CP040605.1\|WP_168584527.1\|587256_588555_-\|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase/GTP-cyclohydrolase-II	gnl\|CDD\|181774	PRK09311, PRK09311, bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II.	0
NZ_CP040605.1\|WP_168584529.1\|589225_590248_-\|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD	gnl\|CDD\|273015	TIGR00326, eubact_ribD, riboflavin biosynthesis protein RibD. This model describes the ribD protein as found in Escherichia coli. The N-terminal domain includes the conserved zinc-binding site region captured in the model dCMP_cyt_deam and shared by proteins such as cytosine deaminase, mammalian apolipoprotein B mRNA editing protein, blasticidin-S deaminase, and Bacillus subtilis competence protein comEB. The C-terminal domain is homologous to the full length of yeast HTP reductase, a protein required for riboflavin biosynthesis. A number of archaeal proteins believed related to riboflavin biosynthesis contain only this C-terminal domain and are not found as full-length matches to this model. [Biosynthesis of cofactors, prosthetic groups, and carriers, Riboflavin, FMN, and FAD].	4.59323e-109

>NZ_CP040605.1|WP_168584522.1|582457_583615_+|MFS-transporter
MSETTEKTVAVPRQARWAVTVYFVITGAALGTWTARIPAIKQDLGLDDAQVTLALFAVAAGSVLAMQVVGHLSDRLGSARVLGPAGIAMAASLLLPGFAGSLPVLVIGLLVFGVGHGTVDVAMNTHSLQVQRRYGRPIVSTFHAMFSVGGLLGAGVGALAAHAEIGVGAHFALVAAALGVVSVIARRGLLPPEERVPGSSVRQRGISPGIVFLGVLAFFCSLGEGSMADWSPLYLHDVLLTSPAVAATGYAVFSAMMATFRFLGDFLVARLGPVVLVRGCGAVAGVGLGGALLLQHPVAAIIGFALFGIGLSCIIPQVFNAAGNRDPSRSGRDLAQVSTLGYGGLLAGPVAIGLISSWTDLTIGLAVPALLAIFVALSARALRPR
>NZ_CP040605.1|WP_168584521.1|581709_582465_+|DeoR/GlpR-transcriptional-regulator
MESSERTLLIIERLRQAERVTVAELAEATRSSEMTIRRDLDQLAEQGVLRRVRGGAVSFLRGHSAPFPVRERDEAELKGRLAVAVEELIADCESVIIDSGTTTLEVAKRLAHRRITAIPLDLHSANALSNASQVDLLMPGGRAKPGELSFTGHLTEASLRALRVDTAILGVCGLSAKHGLTAHDLEEVPVKQAAVSGAQRVVAVCHGAKFARTGLGFVCPITDLDVVVTDRSAPADARAELAAAGVEVRVV
>NZ_CP040605.1|WP_168589742.1|580551_581568_-|dihydroorotate-dehydrogenase
MAQERNLRLVRDVPSELGVRLGDIRLRNRLVTSSSLLGYGVANTKLVPYGMSPISQFVPLARFGAVTTRTVTVEPREGHFTTRDVWPLHELPSLIKRYGQALRQVDGGWLNAFGWCNVGIDAYLRDYYPRTREQNTIISVGGFSAEEFVTLVDKVNAAVPVGEIAAVEFNVSCHNVNFDFNQIIESVLAEAVPRSNHPVILKLSPDYDYLGHARLAARHGVSALTAINTVKGLRLDPNTGQPLLKNGFGGLSGRAIKPIGLRVVKELRDAGVTLPIIATGGIRSFDDCREYFWAGADAVSLGSASWFASYPGYALSPLYAARIWNLLRRIENYTPPER
>NZ_CP040605.1|WP_168584520.1|578965_580045_-|DUF2961-domain-containing-protein
MSGYGEFGSSLRDLPRLRQTRRGRVSSWDRTGGNTDNMRVEPGETRELADIAGPGVITHIWCTVAVDHVGKPAELEGDYLRRLVLKITWDDSPHPAVLVPLGDFFGMGHGRSGNFASAPLQMSPQDGKGFNCWFAMPFAGRARFELISEMSVKPVTFYYYVDYETYGEADPELGYFHAQWRRQNPTDGVEQGDQSNEEFLFGGTNTDGAGNYVLLEAEGRGHYVGTVLNVHNLRQTTDWNWYGEGDDMFFIDGEPWPPRLHGTGTEDYFNTAWCPTQQYQAPYHGLTMPGGPNWSGQVSYYRFHVEDPVVFEKSIKATIEHGHANKRSDDVSSVAYWYQTLPALPVTLAPVTDRLVRPL
>NZ_CP040605.1|WP_168584519.1|576470_578513_-|excinuclease-ABC-subunit-UvrC
MADPSTYRPAPGTIPDAPGVYRFHDADGRVIYVGKAKSLRSRLSSYFADLAGLHPRTRQMVTTATGVRWTVVGTEVEALQLEYSWIKEYDPKFNVRYRDDKSYPVLAVTLHEEFPRLHVYRGPRRKGVRYFGPYAHAWAIRETLDLLLRVFPARTCSGGVFKRHSQIGRPCLLGYIGKCSAPCVGRVSADEHRSIVGDFCDFLAGHTDQLMRKLDKEMQAASAELEFERAARLRDDLEALRRAMEKQAVVLGDGTDADVVAFAEDELAAAVQIFHIRGGRVRGQRGWVIDKVANADGTETGTSELTSQFLTQFYGEQASLADQADAGGSPVPREVLVPQLPDEGDAIAGWLSELRGSRVSLRVPQRGDKRALMETVERNAKESFQQYKLRRAGDLTARSAALQELQEALALDTAPLRIECIDVSHVQGSDVVASLVVFEDGVPRKSEYRRFEVREGAEGGDVGSIDEVVRRRFHRYLSETAKSGTPAEPTGSGPVGAAIDPETGRPRKFAYPPNLLVIDGGAPQANAAADALTELGITDVAVIGLAKRLEEVWLPADPDPVILARTSEALYLLQRVRDEAHRFAISYHRQKRAKRMTSSTLDAIPGLGETRRAALLKHFGSVRKLRQAEVHEIAAVPGIGRRTAETVHSALAAGAETGRRPVPDDRAAPGADNAEGESSD
>NZ_CP040605.1|WP_010310747.1|575599_576478_-|RNase-adapter-RapZ
MTEEQSGIEVAVVSGLSGAGRSTAAKCLEDLGWFVVDNLPPELIATMVELGARSSGAVTRVAVVMDVRSRAFTEDLGAVIKDLDARGYKPKVLFLEATDEVLIRRFEQVRRGHPLQGEGRLADGIAAERSLLSKLRSEADLVLDTTSLSVHQLRSKIEDAFGTEASTRTRLTVLSFGYKYGLPMDADLVMDCRFLPNPFWIPELREFNGLDDEVRNYVLGQEGAEEFLQSYQQLLRLVGAGYHREGKRYLTLALGCTGGKHRSVALAEELARRLAEDDGMMVKTVHRDLGRE
>NZ_CP040605.1|WP_168589741.1|574634_575591_-|uridine-diphosphate-N-acetylglucosamine-binding-protein-YvcK
MRAVALGGGHGLHATLSALSLITPDVTAVVTVADDGGSSGRLRRELGMLPPGDLRKALAALAATDADGQLWSTVFEHRFGGSGALAGHAVGNLVLAGLLEVLGDPVEVLDHACRLLGVRGRVLPMSTVPLDMAADVVGLDSDPEAVRTIRGQVAIASTPGRVKQVRLHANGNEEPAACPQAVRAVLDADLVLLGPGSWFTSVLPHLLVPELHEALVTTPARRVVVLNLVPQPGETAGFSPEQHLDVLSQHAPRLRVDAVLADADSVPTPDRLRAAGAGMGAQTLLDKIAAPAVPGRHDPGALAASLRAALKRRTDRWR
>NZ_CP040605.1|WP_168584518.1|573657_574644_-|DNA-binding-protein-WhiA
MAMTAAVKDELSRLSVTKTCCRRAEVSSLLRFAGGLHIVAGRVVIEAELDSGSTARRLRKEIHELFGHTSDVHMITSGGLRKGTRYVVRVVKDGEGLARQTGLLDPRGRPVRGLPTHVVSGGACDSEAAWRGAFLAHGSLTEPGRSSSMEVTCPGPEAALALVGAARRIGVAAKSREVRGADRVVVRDGDAIGAMLTRLGAHASVLAWEERRMRREVRATANRLANFDDANLRRSARAAVAAAARVGRALELLGPTAPDHLTVAGRLRLAHRQASLEELGQLADPPMTKDAVAGRIRRLLAMADKRARELGVPDTESAVTAEMLEAEA
>NZ_CP040605.1|WP_168584517.1|572310_573321_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MTVRVGINGFGRIGRNFWRAATASEHDIEIVAANDLGDVATMAHLLKYDSILGRLGQEVKVTGEGIEVGGKLIKILAERDPGKLPWGDLGVDVVVESTGFFTNAADARKHVDEGGAKKVIISAPAKGEDLTVVLGVNDDKYDGSQTIISNASCTTNCLAPMVKVLNDTFGIEQGLMTTVHAYTADQNLQDGPHKDLRRARAAAVNVVPTSTGAAKAIGLVLPELNGKLDGYAMRVPVPTGSVTDLTATVRQDVSADSVNEAFKTAAADGKLKGILKYNEDPIVSSDIVTDPHSTIFDAPLTKVIGNQVKIVGWYDNEWGYSNRLADLVDLVAKKLA
>NZ_CP040605.1|WP_168584516.1|570771_571989_-|phosphoglycerate-kinase
MRGADVKNLDDLLSEGVRGRRVLVRADLNVPLDGEKITDDGRVRASLPTVRKLTEAGAQVVLTAHLGRPKGEPDPKFSLAPVARRLGELLGADVALATDLVGDSAKSVVAGLTDGSVALLENVRFDARETSKDDAERGALADELAALVGPDAAFVSDGFGVVHRKQASVYDVAKRLPAYAGGLVLAEVEVLRTLTGDAKRPYVVVLGGSKVSDKLAVIKALLPKVDKLLIGGGMAYTFLAAQGHNVGNSLLQEDQIESTKQLLADHGDKLVLPVDVVAADRFAADAEKQVVAADAIPADWMGLDIGPRSVELFAGILRDTATVFWNGPAGVFEFPAFADGTRGVAQAIVDSDAFSVVGGGDSAAAVRTLGLPEDGFSHISTGGGASLEYLEGKELPGVAVLEGER
>NZ_CP040605.1|WP_168584523.1|584096_584465_-|hypothetical-protein
MLLTIVTIEFGGWFLTKIVRGQVPMTEFQRNFARAGHAHAGVLVTLALVCLVLADATQLTGALGWVARLGVPVAAVLMSLGFFVSSAGRDVHRPNGLIALLWLGALSLAAGVVTLGIGLLVA
>NZ_CP040605.1|WP_168589743.1|584634_584925_-|branched-chain-amino-acid-aminotransferase
MSECAESGQGITQDSVAALAADLGVTVRRVNLLRSDLYAADEMFLCGTAAEVTPVRSVDNREIGEPGPVTRKIQDAFTAAVTGADERYRHWLTHVG
>NZ_CP040605.1|WP_168584524.1|585030_585405_+|FKBP-type-peptidyl-prolyl-cis-trans-isomerase
MSIEKPKVERPTGNPPADLQIEDITVGDGQQAVEGTVVDVHYVGVSHSTGAEFDASWNRGQPLRVQLGKGQVIAGWDTGLQGMKVGGRRKLTIPPHLAYGDRGAGNVIKPGETLVFVCDLVAAS
>NZ_CP040605.1|WP_168584075.1|585521_585680_-|hypothetical-protein
MALTIATLGWRWAFTGLTSSFVLPLLIVGEVALTGAAVYAFPLPPVRRLRMG
>NZ_CP040605.1|WP_168584525.1|586319_586766_-|PH-domain-containing-protein
MSAERVEVRPRKVRRVAIPIAVALVLVFAVAGVLLRNTPTGAFFSVSDQVSMVLLGVLLGAGVLLLTRPRLRADADGVEVRNIIGTQRYSWPLVQAFSFPDGASWARLELPEDEYVPIMAIQAADGEQAITAMRRLRELRRQAGSAAN
>NZ_CP040605.1|WP_168584526.1|586762_587260_-|6,7-dimethyl-8-ribityllumazine-synthase
MSGEGRPRISVPKAGDLRLGIAAIRWHERLVEQMLSRALAAAKEAGIAEPTVVRVPGSIELPVVCQQLAHQHDAVVALGAVIRGGTPHFEYVCDSVTQGLTRVALDESTAIGNGVLTCDTMRQAEERAGFDDSVEDKGFEATAAALETALVLRELRGWDGERGFL
>NZ_CP040605.1|WP_168584527.1|587256_588555_-|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase/GTP-cyclohydrolase-II
MNPEDEVANTVSTNKFDSIERALADIVAGRPVVVVDDEDRENEGDLIFAAEKATPELVAFMVRYTSGYICVGLPGEDCDRLDLPPMYYWNQDRKGTAYTVTVDAAEGVSTGISAADRAKTLRVLAEEASTAKDLTRPGHVVPLRARDGGVLRRPGHTEAAVDLSRLAGLRPAGALCEIVSQKSEGDMARRDELEVFAEEHDLALITIADLISYRRRFEKQVVRVAEARIPTGHGTFRTFGYDSTIDGIEHLALVYGEIGDGEDILVRVHSECLTGDVLGSLRCDCGPQLDAAMAKVAEAGRGVVLYMRGHEGRGIGLIHKLQAYQLQDDGADTVDANVALGMPVDSRDYGQGAQILCDLGVKSMRLLTNNPAKRVGLEGYGLRIVDRVPLPIRPNPENIRYLRTKRDRMGHVLDNLDDGEDSSINGETGVTA
>NZ_CP040605.1|WP_168584528.1|588554_589202_-|riboflavin-synthase
MFTGIVEELGTIEAVEPLADGSRLTIAGPVVTEDAKHGDSIAVNGVCLTVVTVGDGRFTVDVVAETLRRSSMQGIAPGDRVNLERAMALGDRLGGHIVQGHVDGTAVLRGTDADGLTRFDLPQRLSRYLVEKGSITVDGVSLTVVDAGETGFSIALIPTTKELTTLGRREPGDEVNIEVDVLAKHLERLAAAQLVHQDHGAQARSGDNGGVRETR
>NZ_CP040605.1|WP_168584529.1|589225_590248_-|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD
MVARAEEQAMRTAIAASEQVRGTTSPNPPVGCVVLDAGGEVAGVGATRPPGGPHAEVVALRAAGERAAGGTAVVTLEPCSHTGRTPPCTDALRAAGIVRVVHAVSDPNPQAAGGADVLRAAGIDVHSGLLAGEVERGPLRAWLHSARTGRPHVTWKYAATLDGRSAAADGTSKWISSAESRAEVHRMRAQMDAIVAGTGTVLADDPHLTARAPDGTLPARQPLRVVVGDREIPRGAKVFDDAAETIQLPGGDPAAVLAALADRGIVDVLLEGGPRLAGAFVAAGCLDRVLAYIAPLLLGAGPAALGEAGVGSISEAWRLHVEETTMSGPDVRVSAVPLDR
>NZ_CP040605.1|WP_168584530.1|590323_591004_-|ribulose-phosphate-3-epimerase
MIAPSILSADFARLADEMAAVNGAPGQRADWLHVDVMDAHFVPNLTLGLPVVESLLKATDIPIDCHLMIEDPDRWAIGYAEAGAHNVTVHVEAAKDPIAIAKDLRAAGAKAGLSVKPNTPLDPYVEVLKHYDTLLVMSVEPGFGGQSFMAEVLDKARKARELVDTGHLNLLVEIDGGINADTIEQAAEAGVDCFVAGSAVYNADDPAKAVEALRAKAAPNFAHARQ

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Crispr_ID: NZ_CP040605_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_5

1451341-1451523

Orphan

Consensus_repeat	Method
TAGCAAGGGAACCTTCCTGTCACC	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP040605_5

>merge|NZ_CP040605|5|1451341-1451523|CRISPRCasFinder
TAGCAAGGGAACCTTCCTGTCACCCGCGTGCCAATAGCTCCCGGCGTTTCCGCTGCAAGGGAACCTTCCTGTCACCTAACGCCTGCCAGCACGCCTTTCGTGCCGTTGCAGCATGGGAACCTTCCTGTCATCCACACCGGACGCCGTCCCGCGTTTCCGGAGCATGGGAACCTTTCTGCCATC

>NZ_CP040605|5|4|1451341-1451523|CRISPRCasFinder
TAGCAAGGGAACCTTCCTGTCACC	CGCGTGCCAATAGCTCCCGGCGTTTCCG
CTGCAAGGGAACCTTCCTGTCACC	TAACGCCTGCCAGCACGCCTTTCGTGCCGTTG
CAGCATGGGAACCTTCCTGTCATC	CACACCGGACGCCGTCCCGCGTTTCCG
GAGCATGGGAACCTTTCTGCCATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168585170.1\|1461633_1461960_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168585166.1\|1453585_1455802_-\|3-hydroxyacyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|236864
NZ_CP040605.1\|WP_168585164.1\|1451756_1452590_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168585165.1\|1452824_1453103_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168585160.1\|1441278_1442235_-\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP040605.1\|WP_168585161.1\|1444962_1445343_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168589852.1\|1439199_1439634_-\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|181730
NZ_CP040605.1\|WP_168589853.1\|1442580_1444671_-\|penicillin-binding-protein	unknown	unknown	gnl\|CDD\|223815
NZ_CP040605.1\|WP_168585172.1\|1463148_1463913_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168585168.1\|1457122_1458445_-\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|236890
NZ_CP040605.1\|WP_168585159.1\|1439803_1441162_-\|beta-lactamase-family-protein	unknown	unknown	gnl\|CDD\|365903
NZ_CP040605.1\|WP_168585169.1\|1459700_1461185_-\|FAD-binding-protein	unknown	unknown	gnl\|CDD\|183043
NZ_CP040605.1\|WP_168585162.1\|1445335_1445755_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226944
NZ_CP040605.1\|WP_168585158.1\|1438192_1439137_-\|patatin-like-phospholipase-family-protein	unknown	unknown	gnl\|CDD\|132848
NZ_CP040605.1\|WP_168585163.1\|1449209_1449941_-\|cell-wall-anchor-protein	unknown	unknown	gnl\|CDD\|237030
NZ_CP040605.1\|WP_168585171.1\|1461956_1463126_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168589855.1\|1458444_1459662_-\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NZ_CP040605.1\|WP_168585167.1\|1455816_1457031_-\|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl\|CDD\|236197
NZ_CP040605.1\|WP_168589854.1\|1446093_1447236_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NZ_CP040605.1\|WP_168585157.1\|1436649_1438128_+\|sodium:solute-symporter-family-protein	unknown	unknown	gnl\|CDD\|271357

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168585166.1\|1453585_1455802_-\|3-hydroxyacyl-CoA-dehydrogenase	gnl\|CDD\|236864	PRK11154, fadJ, fatty acid oxidation complex subunit alpha FadJ.	2.42079e-152
NZ_CP040605.1\|WP_168585160.1\|1441278_1442235_-\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	9.78804e-11
NZ_CP040605.1\|WP_168589852.1\|1439199_1439634_-\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|181730	PRK09256, PRK09256, aminoacyl-tRNA hydrolase.	3.01129e-56
NZ_CP040605.1\|WP_168589853.1\|1442580_1444671_-\|penicillin-binding-protein	gnl\|CDD\|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	1.19742e-111
NZ_CP040605.1\|WP_168585168.1\|1457122_1458445_-\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|236890	PRK11274, glcF, glycolate oxidase subunit GlcF.	1.84121e-109
NZ_CP040605.1\|WP_168585159.1\|1439803_1441162_-\|beta-lactamase-family-protein	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	1.96057e-50
NZ_CP040605.1\|WP_168585169.1\|1459700_1461185_-\|FAD-binding-protein	gnl\|CDD\|183043	PRK11230, PRK11230, glycolate oxidase subunit GlcD; Provisional.	0
NZ_CP040605.1\|WP_168585162.1\|1445335_1445755_-\|hypothetical-protein	gnl\|CDD\|226944	COG4578, GutM, Glucitol operon activator [Transcription].	1.56879e-10
NZ_CP040605.1\|WP_168585158.1\|1438192_1439137_-\|patatin-like-phospholipase-family-protein	gnl\|CDD\|132848	cd07209, Pat_hypo_Ecoli_Z1214_like, Hypothetical patatin similar to Z1214 protein of Escherichia coli. Patatin-like phospholipase similar to Z1214 protein of Escherichia coli. This family predominantly consists of bacterial patatin glycoproteins and some representatives from eukaryotes and archaea. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein, but it also has the enzymatic activity of a lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have also been found in vertebrates.	8.69931e-49
NZ_CP040605.1\|WP_168585163.1\|1449209_1449941_-\|cell-wall-anchor-protein	gnl\|CDD\|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	6.28241e-07
NZ_CP040605.1\|WP_168589855.1\|1458444_1459662_-\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	5.45303e-44
NZ_CP040605.1\|WP_168585167.1\|1455816_1457031_-\|acetyl-CoA-C-acetyltransferase	gnl\|CDD\|236197	PRK08242, PRK08242, acetyl-CoA C-acetyltransferase.	0
NZ_CP040605.1\|WP_168589854.1\|1446093_1447236_-\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.57882e-49
NZ_CP040605.1\|WP_168585157.1\|1436649_1438128_+\|sodium:solute-symporter-family-protein	gnl\|CDD\|271357	cd10322, SLC5sbd, Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain. This family represents the solute-binding domain of SLC5 proteins (also called the sodium/glucose cotransporter family or solute sodium symporter family) that co-transport Na+ with sugars, amino acids, inorganic ions or vitamins. Family members include: the human glucose (SGLT1, 2, 4, 5), chiro-inositol (SGLT5), myo-inositol (SMIT), choline (CHT), iodide (NIS), multivitamin (SMVT), and monocarboxylate (SMCT) cotransporters, as well as Vibrio parahaemolyticus glucose/galactose (vSGLT), and Escherichia coli proline (PutP) and pantothenate (PutF) cotransporters. Vibrio parahaemolyticus Na(+)/galactose cotransporter (vSGLT) has 13 transmembrane helices (TMs): TM-1, an inverted topology repeat: TMs1-5 and TMs6-10, and TMs 11-12 (TMs numbered to conform to the solute carrier 6 family Aquifex aeolicus LeuT). One member of this family, human SGLT3, has been characterized as a glucose sensor and not a transporter. Members of this family are important in human physiology and disease.	1.82616e-54

>NZ_CP040605.1|WP_168585163.1|1449209_1449941_-|cell-wall-anchor-protein
MSPLSSDELRELREDLSTGTTPTVWFTGSAVGVPEGRSGKVVALGEPAEGDFIQVRPAGSRDVLSFSATEVTKVKPPRKKAAPPEPPAKSAAKPRTADAPPAKPPVGRAKPTAEQAKPAAPAKPRAAAASAPAGASTSAKPAGDAAPRRKPRQAKPIGGATVTLTADQDGQWSVEVSTGKKRVVRPTPVAANAVAQAAKALHDDVAAAVEPLVDAAREQQRARVEQLRAELAAAQAALDELGS
>NZ_CP040605.1|WP_168589854.1|1446093_1447236_-|MFS-transporter
MPEEPRVKDTTALQHRSFRHLLVATVGGFAGYVLLLPVVPLWAVTGGAGEVAAGATNAVFMLVTVLTQLGMPWLLKRIDHRVAFASGTMLIGLPTPLYALSSDLWLLLGVSSMRGVGFGLLTVTGAALVVELVPAAQRGRAAGLYGLSVGLPNVLFLSAGVWLTQQIGFGPLFWIAGALPVAATAAVLGMSRVRAKPAQHSDAPAFPLALLPPWTVMTAAAVAAGGLTAFLPLAVAGSVAPAALMVFGASTMLGRWAAGQFGDRLGQHRVLVPAVLLAGLGTGLLAVAAWGADPLALLGAAAFGAGFGAVQNITLVVMFERTESGPASTAWNIAYDAGHGLGAIGFGALVTLSGYPTTFAVAAILITICIPLTTARRRRS
>NZ_CP040605.1|WP_168585162.1|1445335_1445755_-|hypothetical-protein
MYRSLLTPRWLLLHALFVVATVATGFLAVWQWDRAHEAGGSFQNLGYALQWPLFGVFTIFLWIRLTRMEVHRGDEAEPEAAFQEEAVGPEVTEEAPPVMRRKRPLVPPPAPPVDAGGDPELAAYNQYLAELNETDRRAS
>NZ_CP040605.1|WP_168585161.1|1444962_1445343_+|hypothetical-protein
MTDPFLDSLATALAGQVATALGKAGSQALVKVRELVRRRSQNDPETQAALEAAEQESAGKPQIKALAERLDQVCGEDAAFAEQLRAEGAEVHKAISAADDGVVNVNHGEVNNLIQAREIKGNITFS
>NZ_CP040605.1|WP_168589853.1|1442580_1444671_-|penicillin-binding-protein
MRSGVLLKMFGLCVLAGVLVAALLLPMATGAGAMVNQTSDAMSRMSGSLARRDMPQVTTVTDKDGAPIAYFFKDYRIETPPDQISDTMKAAITAVEDKRFWDHGGVDWHGTMRALATNVSSGSAAQGASTITQQYVKNYLVHVAANNAVEAEKAKESTVARKLREAKIAVELEHTMTKEEILTGYLNVVPFGNQTFGVGAAAQTYFGTTSDKLTIAQAALLAAIVNQPGSLNPNSNPQDAMQRRNLVIDLMADPNNNIRITKEDAEIAKKEPLGVMSPLGRPPNGCVGVGDGATDGFFCTYLVDYLDRLGIDSDKLKSGGYTIRTTLDRKATDAAKAAAEAQVPTQTEGIANAMAMVEPGKDKHKVRALVANRDYGNDASKGQTAYDIVSRVQPFGAGSIYKVFTAASAIEQGMSIYDTLDVPPSYTSRVYKNGTAPYTVSNADGVQPGPRTLQMALATSPNTAFVALQERAGLNNVVDMAARLGLRNGMTAVNTSGQGLKPDGSNGPSQADAIKKGNRGAFTLGYTPTSVLELSNVAATIMSDGVYCPPTPIEEIKDRHGNPVQLNEPGCEQAVSPQVAAALAQGMSKDDTDGTSRAAAQSVGWNRPMIGKTGTTQLHQSAGFLAATPQMAGAVLTYADGNSPQGICDGGGDAPPYLCGKNGGNIYGGKVPARTWFAAMTKVHEGLPAAPLPGTP
>NZ_CP040605.1|WP_168585160.1|1441278_1442235_-|CPBP-family-intramembrane-metalloprotease
MSTEHDRVDVRGVVSFVAITYVPAWLLTLPLWLTGKGLSWNWAPLFLAVMMFMPAVAALVVNKWISPRPKLLRSLGITNPGGIKKWWPYVLIAWVGPPLVMALALLVGYLLGVYQADWTGFSGLAEQAGPTVVGSAPQTPPGVIALIQIAMVFGLGWLQIIPALGEELGWRGYLTQALLPLGQPGAFLTTGVLWGLWHVPVLILGYNYPTLPIVVAVIMMVCFCTLVGTLLGWLRLVSRSVWPPTIAHGFLNAAAGLGTVFSMAGHPVDNASVGLLGWTGWIVLVLLILVLAMLGKLPVQFPAEMVGITRGVNRRSRR
>NZ_CP040605.1|WP_168585159.1|1439803_1441162_-|beta-lactamase-family-protein
MTSLLPSTQRALLRRLAVEQSENRVPSLIAGLIRDGETIWVDTRGQVGGRPSTTDTQYRVGSITKTFVAVLVMRLRDEGRLDLADKLDEYVPGTSIGKQSIGQILSHSSGLTAEPAGQWWERTPGGSADELLSTIDEHARRPTPRHGFHYSNVGFGVLGELVSRLRGAPWGEVLQREILEPLGMKRTTLSPVAPHAEGFAVHPWADVVLPEPAEDAGAMAPAGQLWSTFEDMASWARFVSGDTGEVLHPATVAEMRLPGSVDDGPEWRGGYGLGLQLMRYRGRRLAGHTGSMPGFLATVWTDPAEATGVIFMANTTAGVTGALATDLLDLLAEHEPRIPAAWEPRGDVDLQLLELTGQWYWGPTPYALRVLRDGLLDLSPWQGRGRASRFRANPDGTWTGLDGYYAGEILRVGRDESGVPTHLDLNTFIFTRTPYDSDAPVPGGVAGWRPAR
>NZ_CP040605.1|WP_168589852.1|1439199_1439634_-|aminoacyl-tRNA-hydrolase
MPADLPVTSRWTIPAAELSERFSRSSGPGGQGVNTTDSRVELSFDLARSASVPELLRQRSMERLAHRLVNGVITIAASEYRAQLANREAARERLAKLLAESVAPPAPKRRRTKPTKGSQQRRLAGKKRRGEVKRQRRRGDPGDG
>NZ_CP040605.1|WP_168585158.1|1438192_1439137_-|patatin-like-phospholipase-family-protein
MRTAWVLPGGSTFGAIQAGLVTALFEAGVEPDLLVGTSAGSLNAAWFAGDPTPRGAAKLRELWMSMRRTDVFPIQPTRIFAGKLGLSNHVMGNHGLARWLHNNLPFRRLEDAQISVTVTATDLDTGEPVYFESGPALPPLVASCSIPGMFPPVKVGDRWLVDGGPAAFMPISRAVERGAERVFVLPCGGTEPFEFNRRRRGIGSIATWPPPKTPPRSVGGVNGAALGAAMVSAARLDMQLNATRCELYVVPAPSVVGLSPYSFAHAGALIDASWEIAKRWYPTAKPVPSGPVDIGGNPSTSGRFGVSESAPNAQ
>NZ_CP040605.1|WP_168585157.1|1436649_1438128_+|sodium:solute-symporter-family-protein
MSTSAAVSVGIFAVFMLAAVALGLLSLRGRDRANLAEWSIGGRSLGVALIFVLMAGETYTSFSYLGAAGWSYNYGMPVFYLLAYLAIGFAVGYVIGPILWHYAHRNKLHNITDITTYRFDSPWFGAAVAILTTVFLLPYIQLQITGMGVVVSTISYGTISLGTGYLIAFVVTEAFIIFSGLRGSAWVSILKDSLVIITLLVVFICVPVEYFGGLGPMLDRLVAERPEWLVLPGQGTESLGMLWFATTGLLNGVVYTIFPTTVAGYLGAKNPGVLRRNAIIMPFYQVLLFVPILLGLAAVFVVPGLEDSNLAMFKLVVDSMPAWLVGLVGVAGALSSIVPMAVFMLVIGTMWGRSVLGVHPRTAPHQKQLSQLVTFLVGLVAFVFTFISPSTLVQLSVLSYQGLAQLLPVVLISLLWKRMSTAGAASGLAAGVVVVAVLVVTGNDPWLGINVGLLGLAVNILVNLAVTLARPATAPPERLAVDELSEAVSPRA
>NZ_CP040605.1|WP_168585164.1|1451756_1452590_+|hypothetical-protein
MRPWTTRTVKAAVVAAGFAAVGTGATAAAESTALPKPDLSPVPDQIGVLAPLNACQLQDGPGYGPTKAPCADTELHVNTPNLVKKVGADITTTAHGMGGELRDGRPLLAPGKPNQVLGHVFAETTRVEQMTKTRPAVGGSVVPNHLGVVTERIPNAALLDTEVGPREPGHQGTSALDTAIDLTAAQGYETEPLANPVGAVAPVLQNDLRPGAPVALPQAARLLPAVGKLPVTSELNGGLGPAANDLTQQATGLLPQAPVHRITGQLPTIDSVTRPLR
>NZ_CP040605.1|WP_168585165.1|1452824_1453103_+|hypothetical-protein
MFSHLRRSTVRIGAAIAGVATTAAAMMAIASPAFADSANNHGVNLLDDNNASAVPVQACGNNVAVLGAVVSLLSPQINNCVNAPIVDHPKMG
>NZ_CP040605.1|WP_168585166.1|1453585_1455802_-|3-hydroxyacyl-CoA-dehydrogenase
MSEQNTIRWESDADGIVVLTLDDPQQQANTMNERYQRSMAETVQRLEDERDNITGVVLTSAKSTFFAGGDLRELVQARPGDAERVAETITGVKRQLRRLETLGVPVVAALGGTALGGGLEIALACHHRIALKNPKASFGFPEVTLGLLPGAGGVVRTVRLLGIADALLNVLLQGQRLRPEKAAEIGIVDQLVDTPEQLLTAAKEWIKANPDAAQPWDRPGHKIPGGTPSNPKFAANLPAFPANLRKQLKGAPLPAPRNILAAAVEGAQVDFDTALTIEGRYFVELVCGQTAKNMSKAFFFDLQHINSGGSRPAGEPEWRAQKVAVLGGGMMGAGIAYVCAKAGMEVVLKDISLAAAGKGKDYSAKLLEKAIAKGRSTQAKADELLARITPTDQLEPLAGCDLVIEAVFEDPKIKHQVYAEVQDVVEGDALIASNTSTLPITGLAEGVRRREDFIGLHFFSPVDKMPLVEIICGEHTSERALARAFDVVQQINKTPIVVNDSRGFFTSRVIGTFVNEGVSMLAEGVHPASIEQASAQAGFPAPVLQLFDELTLTLPRKIRDETKRAVEAAGGIWTPHPAEQVLDRMVDEFDRKGRSSGAGFYDYVDGKRVGLWPGLVEHFGTAERDPAEVSLTDLTERMLFVEALETVKCLDEGVLRSVPDANIGSILGIGFPAWTGGVVQYMNGYPDGLAGFVARARELAERYGQRFEPPASLVHRAEAGEPFDLGEPDPAIVAATAA
>NZ_CP040605.1|WP_168585167.1|1455816_1457031_-|acetyl-CoA-C-acetyltransferase
MSEAFVYDAIRTPRGRGKKTGSLHGVKPISLVVGLIQELQRRHPQLDPALIDDIVLGVVSPVADQGGDIAKAAALAAGLPDTVSGVQLNRFCASGLEAVNIAAQKVRSGWEDAVLAGGVESMSRVPMGSDGGAWAMDPETNFATSFVPQGIGADLIATIEGFDRTTVDAYAAESQNRAAKAWADGRFARSVVPVTDRNGSTVLDRDEHIRANTTVDSLGGLKPSFADIGELGGFDAVALQKYHWVERIDHVHTAGNSSGIVDGAALALIGGEALGERTGLRPRARIVAAALSGADPTIMLTGPGPAVRKALGKADLSIDQIDLIEINEAFAAVPLKFMKEFGVSHDNVNVNGGAIAMGHPLGATGAMILGTLIDELERRNLRYGLATLCIGGGMGIATVVERIG
>NZ_CP040605.1|WP_168585168.1|1457122_1458445_-|4Fe-4S-dicluster-domain-containing-protein
MTETPARPGAFDALHPPQRELVDDCVHCGFCLPSCPTYDLWGEEMDSPRGRIYLMKEGLEGEPMTDTMVGHFDACLGCMACVTACPSGVQYGTLITETRAQVERNHQRGRWERLLRTAIFTLFPYPRRLKAMRGPLALYQRLGIGNLLKRSGLQALLPDGLQVMESLVPPIGRAPKLGHRIPARGKRRATVGMITGCVQSAFFPDVNAATARILAAEGCDVVIPPAQGCCGALSEHSGREEEAIKFARDLLDTFEESGVDYVVINSAGCGSTLKEYPRLLQDDPEYAERAERFSARVRDIAELLVELGPVAKRHPLPVQIAYHDACHLAHGQGIRSQPRELLRAIPELELKEINRGELCCGSAGVYNLLQPEPARELGDRKAENVLATGAKLLVTANPGCSMQIRTALERRGEHLAMAHTVQVLDASIRGQGVETLLPRV
>NZ_CP040605.1|WP_168589855.1|1458444_1459662_-|FAD-binding-oxidoreductase
MAALGSECVRDATNTDVVSGVRPHWVATVDGTERTSVAMKVAAEHGLRMVPKGSGSKLDWGSAPEAVDLLLDVSAAKGIVDHAAGDLVVHALAGTPIAEVNNTVRAAGQQLAIDQPLPTATLGGIIATGTAGPCRHLFGGVRDLLIGITVVRADGTVTTAGGKVVKNVAGYDLGKLYTGSFGTLGVITEAVFRLHPVAAEHRWITVTTDAPATAATAADIVRHSQAMPTAIELDRPEPAGPITICAQLEGRPNATHDRAVELAAAIGHGAEVLDKAPSWWGRYPFDPVGGIGLRLGAEPTALPRVLSGAQEAAAASGLPLAIRGAAGLGVLNAGLPGDTDPAAVVELVKALRTGCDYAVLVRAPKDAAIDPWGPIAPGLLALMRRTKDQFDPEHRLGPGRFVGGI
>NZ_CP040605.1|WP_168585169.1|1459700_1461185_-|FAD-binding-protein
MQSTSTEAEQALDQVVQRFRAALPPNAVITDPQRLRTYECDGLASYRVVPAVAVLPETAEQVRQIVRICAEHQVPFVARGSGTGLSGGALPHASGVLVVTSKMRRILEIDLANERAVVEPGVINLDVTKAVAAQGYYFAPDPSSQQVCSVGGNVAENSGGAHCLKYGFTTNHILDLEVVTPDGDIVELGGDAREAPGYDLLGAFIGSEGTLGVVTKITVRLLRKPEAVQTLLAGFPSTDEAGAAVSAIIADAVTPAAIEMMDALAIEAAEQAVQCGYPEGAGAVLVVELDGPAAEVAHTFAEVKRHCEAHGAFEIRVAADDGERAMIWKGRKSAFAAVGRISPDYIVQDGVIPRTALPEVLGRIARLSAESGVRVANVFHAGDGNLHPLVLFDDAEPGANDRAEAVSSAILDLCIEHGGSITGEHGVGADKVKYMGRMFTADDLDTMQRVRCAFDPVGICNPGKVFPTPRLCGEVPGPRRGAHPLTEAGLADQF
>NZ_CP040605.1|WP_168585170.1|1461633_1461960_+|hypothetical-protein
MGGELRMTPGTLSGHGGGCESLADKFGQLAQLLEQARTDDQCFGPIGNAVGISDKYFETLQGCQEMAQKAQQFLVETKQSLDDTVKDYNDTEQQIIELLNKAGEGLAG
>NZ_CP040605.1|WP_168585171.1|1461956_1463126_+|hypothetical-protein
MTGPGTFTELNQGDSTRKNWAEQTLTRGSSAANAAYGLRDAAVNTDGGSFADGSAAPEWTSAVISARQEQMELLQNPGQALLDNGLGFLVSIVMTPLIEIAEQAIGDPEQMRATGKGWEEVAKWLDSVGEQEPKRAEATAASWVGQDGDAFRNQMNEFGEGTKALAQDVRGLKETLDGIADMFDMFVELVINILTELIISLIIQWLAALAASWITAGASVGAASATTTASVGITGGRIAAQVAKIQAQLYKWLKKLEELLNKIRESGRLGRLLTRQLSKGKIEQVKDPNTGEVLREFATSKTSNVFMKSQGLHKTGEEALAANLAGKVIGGALGGKASLGGAAVSGVMETAEGQAVKEIPKAMYDETNQRISGQLTPEESKSAQEKGFS
>NZ_CP040605.1|WP_168585172.1|1463148_1463913_+|hypothetical-protein
MTLDHLILSARSWWCEPGEPIVWAFPDPYHIPLFEVDGLDEHGKRRRNILTRAAFQVGSLPFRINSLMTWGDEPADQRNLPTAVVAARGADATAVRMTGTQGEASPGELPGVLVATPGRLALLELTEIPEGSKDWFDKGLEKIKKATGPAYQLADDFAGTMGSTINNKGRYFDHDGQTRTPQVVERANVGTEQISGYGVVPREFRGHDYDKDNRSSSYLRINFADGSRLELRIPAGTDPNRVLGLVRGNGVGSW

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Crispr_ID: NZ_CP040605_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_6

1506932-1507063

Orphan

Consensus_repeat	Method
CGACGTGAGCATGGGAACCTTCCTGCCA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP040605_6

>merge|NZ_CP040605|6|1506932-1507063|CRISPRCasFinder
CGACGTGAGCATGGGAACCTTCCTGCCATCGCCCAACCATCGGAGAGGTCCAGCGACGTGAGCATGGGAACCTTCCTGCCACTCCGGGCACTGGCCACGCCTGGCGTTGCGAGGAAGGGAACCTTCCTGCCA

>NZ_CP040605|6|5|1506932-1507063|CRISPRCasFinder
CGACGTGAGCATGGGAACCTTCCTGCCA	TCGCCCAACCATCGGAGAGGTCCAG
CGACGTGAGCATGGGAACCTTCCTGCCA	CTCCGGGCACTGGCCACGCCTGG
CGTTGCGAGGAAGGGAACCTTCCTGCCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168585205.1\|1500965_1502522_+\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379258
NZ_CP040605.1\|WP_168585207.1\|1504412_1504640_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168585214.1\|1519293_1520208_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176115
NZ_CP040605.1\|WP_168585204.1\|1500226_1500598_-\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_CP040605.1\|WP_168585215.1\|1520614_1521772_-\|imidazolonepropionase	unknown	unknown	gnl\|CDD\|237604
NZ_CP040605.1\|WP_168585211.1\|1511656_1515334_+\|multifunctional-oxoglutarate-decarboxylase/oxoglutarate-dehydrogenase-thiamine-pyrophosphate-binding-subunit/dihydrolipoyllysine-residue-succinyltransferase-subunit	unknown	unknown	gnl\|CDD\|237030
NZ_CP040605.1\|WP_168585210.1\|1507289_1510964_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP040605.1\|WP_168585206.1\|1502837_1503953_+\|alanine-dehydrogenase	unknown	unknown	gnl\|CDD\|240630
NZ_CP040605.1\|WP_168585213.1\|1518109_1519297_+\|glycine-C-acetyltransferase	unknown	unknown	gnl\|CDD\|235893
NZ_CP040605.1\|WP_168585201.1\|1496870_1497722_+\|NmrA-family-NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|187578
NZ_CP040605.1\|WP_168585212.1\|1517069_1518110_+\|L-threonine-3-dehydrogenase	unknown	unknown	gnl\|CDD\|180054
NZ_CP040605.1\|WP_168585208.1\|1505102_1506071_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213235
NZ_CP040605.1\|WP_010304877.1\|1515668_1515845_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168585216.1\|1521807_1523124_-\|formimidoylglutamate-deiminase	unknown	unknown	gnl\|CDD\|236420
NZ_CP040605.1\|WP_168589856.1\|1523129_1524311_-\|allantoate-amidohydrolase	unknown	unknown	gnl\|CDD\|236456
NZ_CP040605.1\|WP_168585200.1\|1495758_1496874_+\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223737
NZ_CP040605.1\|WP_168585209.1\|1506070_1506925_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|372253
NZ_CP040605.1\|WP_168585202.1\|1497738_1498614_+\|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223528
NZ_CP040605.1\|WP_168584080.1\|1516609_1516915_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239487
NZ_CP040605.1\|WP_168585203.1\|1498843_1500199_-\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|273233

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168585205.1\|1500965_1502522_+\|PucR-family-transcriptional-regulator	gnl\|CDD\|379258	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain. This helix-turn-helix domain is often found at the C-terminus of PucR-like transcriptional regulators such as Bacillus subtilis pucR and is likely to be DNA-binding.	9.45118e-16
NZ_CP040605.1\|WP_168585214.1\|1519293_1520208_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176115	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.27803e-55
NZ_CP040605.1\|WP_168585204.1\|1500226_1500598_-\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	5.71611e-58
NZ_CP040605.1\|WP_168585215.1\|1520614_1521772_-\|imidazolonepropionase	gnl\|CDD\|237604	PRK14085, PRK14085, imidazolonepropionase; Provisional.	0
NZ_CP040605.1\|WP_168585213.1\|1518109_1519297_+\|glycine-C-acetyltransferase	gnl\|CDD\|235893	PRK06939, PRK06939, 2-amino-3-ketobutyrate coenzyme A ligase; Provisional.	0
NZ_CP040605.1\|WP_168585210.1\|1507289_1510964_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.3807e-157
NZ_CP040605.1\|WP_168585211.1\|1511656_1515334_+\|multifunctional-oxoglutarate-decarboxylase/oxoglutarate-dehydrogenase-thiamine-pyrophosphate-binding-subunit/dihydrolipoyllysine-residue-succinyltransferase-subunit	gnl\|CDD\|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0
NZ_CP040605.1\|WP_168585201.1\|1496870_1497722_+\|NmrA-family-NAD(P)-binding-protein	gnl\|CDD\|187578	cd05269, TMR_SDR_a, triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs. TMR is an atypical NADP-binding protein of the SDR family. It lacks the active site residues of the SDRs but has a glycine rich NAD(P)-binding motif that matches the extended SDRs. Proteins in this subgroup however, are more similar in length to the classical SDRs. TMR was identified as a reducer of triphenylmethane dyes, important environmental pollutants. This subgroup also includes Escherichia coli NADPH-dependent quinine oxidoreductase (QOR2), which catalyzes two-electron reduction of quinone; but is unlikely to play a major role in protecting against quinone cytotoxicity. Atypical SDRs are distinct from classical SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.82545e-70
NZ_CP040605.1\|WP_168585212.1\|1517069_1518110_+\|L-threonine-3-dehydrogenase	gnl\|CDD\|180054	PRK05396, tdh, L-threonine 3-dehydrogenase; Validated.	0
NZ_CP040605.1\|WP_168585208.1\|1505102_1506071_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213235	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter. The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.	3.77938e-92
NZ_CP040605.1\|WP_168585216.1\|1521807_1523124_-\|formimidoylglutamate-deiminase	gnl\|CDD\|236420	PRK09229, PRK09229, N-formimino-L-glutamate deiminase; Validated.	2.15187e-169
NZ_CP040605.1\|WP_168589856.1\|1523129_1524311_-\|allantoate-amidohydrolase	gnl\|CDD\|236456	PRK09290, PRK09290, allantoate amidohydrolase; Reviewed.	2.59561e-164
NZ_CP040605.1\|WP_168585200.1\|1495758_1496874_+\|FAD-binding-oxidoreductase	gnl\|CDD\|223737	COG0665, DadA, Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism].	4.71013e-16
NZ_CP040605.1\|WP_168585209.1\|1506070_1506925_+\|ABC-transporter-permease-subunit	gnl\|CDD\|372253	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family.	9.79724e-06
NZ_CP040605.1\|WP_168584080.1\|1516609_1516915_+\|hypothetical-protein	gnl\|CDD\|239487	cd03393, PAP2_like_3, PAP2_like_3 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria and archaea, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	0.00232224
NZ_CP040605.1\|WP_168585202.1\|1497738_1498614_+\|NAD(P)-dependent-oxidoreductase	gnl\|CDD\|223528	COG0451, WcaG, Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	2.69285e-23
NZ_CP040605.1\|WP_168585206.1\|1502837_1503953_+\|alanine-dehydrogenase	gnl\|CDD\|240630	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains. Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.	0
NZ_CP040605.1\|WP_168585203.1\|1498843_1500199_-\|L-serine-ammonia-lyase	gnl\|CDD\|273233	TIGR00720, hypothetical_protein_NEICINOT_00681, L-serine dehydratase, iron-sulfur-dependent, single chain form. This enzyme is also called serine deaminase and L-serine dehydratase 1. L-serine ammonia-lyase converts serine into pyruvate in the gluconeogenesis pathway from serine. This enzyme is comprised of a single chain in Escherichia coli, Mycobacterium tuberculosis, and several other species, but has separate alpha and beta chains in Bacillus subtilis and related species. The beta and alpha chains are homologous to the N-terminal and C-terminal regions, respectively, but are rather deeply branched in a UPGMA tree. This enzyme requires iron and dithiothreitol for activation in vitro, and is a predicted 4Fe-4S protein. Escherichia coli Pseudomonas aeruginosa have two copies of this protein. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	0

>NZ_CP040605.1|WP_168585209.1|1506070_1506925_+|ABC-transporter-permease-subunit
MGGLVKAEFRKIFSTSLWWALLIPVALLGFGAGWLGSSIVALIDAVEQFDRAVPLGLLSVSMSTNFSTIFAALFGAMAFAGEFRNKSITTTYLTSNPRSAVLAAKLIACSGVGLIYGLANVLFASVGGLVGAGRDFGGFGSLGDWLSVGAAAVLAMVLWTLLGVGFGALVANAVLAIIVPLVYKFMVEFILSLSLIESPAAGISPYLPGTAGNGIVANLAVPLFVTAVAGPDEPNTPRAAFEFLHLFFGGSYGHPWWASLLTFLGYAAVFIAGGWLVSRRRDIS
>NZ_CP040605.1|WP_168585208.1|1505102_1506071_+|ABC-transporter-ATP-binding-protein
MHDGSGRLIVQGLSKSFGPVNAVQDLNFTVRPGSVTGFLGPNGSGKTTTLRMLLGLVTPTAGTATINGLPFHQLPNPATVVGAVLDAQSFHPGRTARQHLRCYAAAMNVPDAQVDRALELVGLSAAAKRKAGTFSLGMRQRLALATALLGDPQVLVLDEPANGLDPEGIAWLRNFLKAFAASGRTVLMSSHFLREIEHTVDQLVIISRGRCVFDGHLDQLRAAQRSRALVQAADPSKLVDKLQEAGYSIEYLPDGRIAVTGSDSRAVADLALEAGIALYGMQDERIGLEQLFFQLTNGQYNGVQQHGAQWSAPGGQGFGGNA
>NZ_CP040605.1|WP_168585207.1|1504412_1504640_+|hypothetical-protein
MRRAVLDQLDGVDLTTADDTPEVLLPLARTQLYLLTSYYLLTSAPCSTNTIRTRPAGAAPARARRAAGRGRAPCG
>NZ_CP040605.1|WP_168585206.1|1502837_1503953_+|alanine-dehydrogenase
MKIAVPREIKNNEYRVAITPAGVHELTTRGHDVFVETNAGAGSSIPDEDYLAAGAKVLPTAEEVWAEGQLVLKVKEPIAEEYPRLRRDQVLFTYLHLAASAELTDAMLKSGVTGIAYETVQTANGSLPLLAPMSEVAGRLAPQVGAYSLMRPSGGRGVLPGGVPGVHPARVVVIGGGVAGLNAARVAMGMGADVELLDTNVDKLREIDRDFHGQIRTVTSNRYSVEQAVRAADLVIGAVLIPGAKAPKLVSNHLVSEMKQGSVLVDIAIDQGGCFADSRPTTHDDPTYRVHNSVFYCVANMPGAVPNTSTHALTNVTLPYVLRIADQGWQQACRADAALAGGLNTHDCKLVNEPVAEAHGLTSTPLSSVLG
>NZ_CP040605.1|WP_168585205.1|1500965_1502522_+|PucR-family-transcriptional-regulator
MLDIRALVERVGPTLLRTVVAPEPRVCVGDVVIAEPDEPPTAAGGDLVLGVAIPDREHAVALTRDCGAKGAAAVLLKPPISADDAVAAAARDAGVALVEVRPGTAWAQLVWLIRAALAGTDIEEADAPSTGVGDLFRLADAVADVVDAPVTIEDARSQVLAYSARQDLTDPARVSTIMGRRQPDDVLAKFRARGTFRQLSKGSSAIFVPAQQDGTLPRLVVPIRMGGELLGSMWAVVPGEVSEERSTAFADTAPLVALQLLRWRAVADAERRRSAEQVRLLLEGGEGWRAAANELAVPAEAHRVVAIEMPPSASPAEGHRLAMWEWITRGIGRRPLVTEIGTMLYALVPDRGRAGGWPDLRAALTSHDVSPRPLIAVGTAVAVAELPQSRSQAEELISLLRTGQLQQRVAVYEENWHLLVLSRMAGAATDAGIGALGPLPVLREHDRTQGTEYLATLHAWLRHPGDPRQASRELRVHPNTFRYRMKRLTQLVDVDLEDPNVRSALFAQLLADRWAQHG
>NZ_CP040605.1|WP_168585204.1|1500226_1500598_-|glycine-cleavage-system-protein-GcvH
MSLPAHLRYSEEHEWIEDRDELVRIGITQHAADALGDIVYVQLPEVGDKIEAGQACGELESTKSVSDLFAPVTGEVVALNESVVDDPALLNAEPFGDGWLLEVRPTSTGSLLTAEQYAELIAE
>NZ_CP040605.1|WP_168585203.1|1498843_1500199_-|L-serine-ammonia-lyase
MAISVFDLFSVGIGPSSSHTVGPMRAARLFVQRLHSAGRLPQVERIKAELFGSLGATGHGHGSPKAVLLGLEGHSPETVDPAAVEGRVTEIRDSGRLRLDGVQQIRFIVDRDLVMHRRKSLPLHPNGMRFAAFGADDAELDSAVFYSVGGGFVVDEDATGTDRIKPDETAVRYPFRTGVELLARTEQSGLPISGVMLANELSWRGEDAVHKELLGIWQVMRECVDNGCRNSGELPGGLKVRRRAAELAASLTERDDPLEWVTLFALAVNEENAAGGRVVTAPTNGAAGIVPAVLHYYTRFAPGADDAGVVRFLLAAGAVGVLFKENASISGAEVGCQGEVGSACSMAAAGLAEVLGGTPRQVENAAEIAMEHNLGLTCDPIGGLVQIPCIERNAVASVKAITAARMALRGDGSHFVSLDKVIKTMRETGRDMKVKYKETARGGLAVNVIEC
>NZ_CP040605.1|WP_168585202.1|1497738_1498614_+|NAD(P)-dependent-oxidoreductase
MHVFAIGASGVLGRHLVPMLLRRGHDVTVMAPDRLDRLPGEARRVRASLLDPAAERLLAAEFKEVDAVVNAATAVPAMPTAPGGWARNTALRSTGTAVVTGALQEAEVRRFVQMSITMVYADGGDDKLTEAAPLDHRPERATLVDPVLAMETAVRKLPADEIAWSILRGGRFVGPGTVQDQQRARLRAEDLPIPGAGREWVSMVHARDYADAVVAALERGCAGKTLNVADQPVRVADYYRDLARADDSPPPRHDPNAAAEPSHRVSSEAARQLLGWAPVHGIWPLGDDEDR
>NZ_CP040605.1|WP_168585201.1|1496870_1497722_+|NmrA-family-NAD(P)-binding-protein
MTLTVAGASGVVGRAVTRELVRLGHRPRVLVRPGSPNRDLSPDATVVECDLTDRAATLRALHGSERLFLLTPFHSEQLVLQRNLIAASAEAGVKRVVKLSALGARPGAESSIHHQHGVGDDELRASGLPHAVLRPNAFMQNALQWLPTIRRRDAIVLPVGAARVSMIDVGDIGLAAVTLLTSDAVGDYDLTGPEALSYREVASILSEVAGRRIRHVDAEPAEVAAAMRSAGVPDWAVAARLQLYATYRAGDAEVVTTAINDITGRPPRDYRSFAAGLAEQLRN
>NZ_CP040605.1|WP_168585200.1|1495758_1496874_+|FAD-binding-oxidoreductase
MAEHKRELDIAVIGAGVLGLSTTDALLRRGADVKCFDGRRPGAGQSGGLSRTFRHRHDDPHIVDLAVRGLAGYREWERRSGVEMVGTEGCAYLGTTADDTLGLKAHQVPHHYVPEADREQVFGALGPIGGPLLVDPTAGALRVNHVIETLTGWVGGHIVANDIHSLLVLDNGKVEFQTADAIYHARHVVLCAGVDTPRLAARLGWDIPLDCALHARPHYRIREELRGAPTPCWVDKSGEFGEMVYGSVIPYTDQYVLGLIGDGVDVPFDARGALTGEEGMEDHVRRVTGYVERALPGLIPEPVGVRVCIMSKLPAGSDALRAWHAPGVTAIAGHNLFKFAPELGELLADSAVDDGLPADLELAGARALGAA
>NZ_CP040605.1|WP_168585210.1|1507289_1510964_+|ABC-transporter-ATP-binding-protein
MGASVTAVGLEALVPLLTKAAVDDAVAHSTDRLLWIVIALLTLGVFRFASAFVRRYSAGRLALDVQHDLRRAVFAAMQRLDGGKQDALRTGQVVSRSISDLQMVNSLLSMLPLAAGTAVLALFAIVVMLWLSPLLTVVSLVVAPLIAVVSARSKKSLFPATWSAQQRAADIAQHVEETVTGVRVVKGFGQEDREVGRLERRARRLFGERLRAARMTSMPAASLAALPSAGQVGVLGLGGWMVLQDQVSLGTFVAFAGYVAMLAGPARMLSSVMIQAQLARAGVERIHELIDSQPEVQEKPGAATLPEGPLQVRLDDASFGYTRDQPVLCNASLQVRPGETVALVGPAGSGKSTVSLLLPRFYDLHSGSIKIGPADDGSVSHDIRDLRLDSLRAAVGLVFEEAFLFSDTIRGNIAYGRPDASEADVIAAAKAAEAHEFISTLPDGYDTTVGERGLTLSGGQRQRVALARALLSNPRILVLDDATSAVDPATEAAIHDTLRLVTAQRTTLLIAHRRSTLALADRIAVLDEGHVVDIGTEDELNQRCELFRSLLAGPGELIDNRCDGRVVPGSEGITPELWPPEDDAEPAVTGNAATTPGSRGMGGMTMPPTPELIEGIRKLPPATDQPDLRGEDPTAPDPDFKLPRLLRPIRWGLLLTALLVAGDALTSIALPSLVRQGIDGGVSAGDLDALWIATGLGAVIVAGGWLVVKLQTVITSRTGETLLYLLRLRSFAHLQRLGLDYYERELAGRIMTRMTTDVDALSTFLQTGLATFVVSVLTLFGIAGALLITDVSLALVAMAVLPVLLVATLIFRKVSATAYAEARERVSTVNADLQENVAGMRVAQAHRREGHAAKVFAQRSDAYRRSRLRAQRYIATYFPFVALLSEIAQAVVLGVGAARVASGDLTAGVLVAFLLYLGLFFSPVQQLSGVFDGYQQAKVGLRRIGELLRTPTSVPAATDPTPVPERFEGGIELRSVSFRYPGTDQFALRDIALRVRPGETVALVGATGAGKSTLIKLIARFYDATDGAVLVDGQDIRSYDLAAFHRRLAVVPQEGHLFTGDIATNIAYARPDADPAEVEAAARAVGALPGIAMLPRGFRQQVGERGRGLSAGQRQLVALARAELVDPDVLLLDEATAALDPATESMVVAASDQVAAQRTTFVVAHRLATAARADRIVVVDGGRIVEQGSHAELLADNSYYARLWRAADGAPSEETPEIGETNIA
>NZ_CP040605.1|WP_168585211.1|1511656_1515334_+|multifunctional-oxoglutarate-decarboxylase/oxoglutarate-dehydrogenase-thiamine-pyrophosphate-binding-subunit/dihydrolipoyllysine-residue-succinyltransferase-subunit
MSSSPASQFGPNEWLIEEMYEQFLQDPTSVDSAWHEFFADYKPGQAAIENTAAAAAAAAAPTTTATVTRPSETNGQAPPAAATTAPPASKPAPKPSPQQAARAAPVKEPQAGGDVKTLRGAAAAIAKNMDQSLTVPTATSVRAVPAKLLFDNRIVINNHLKRNKGGKVSFTHLIGYALVRAVRDFPNMNRHYGEDAKGKPAAVTPEHINLGLAIDLPAKDGSRNLVVASIKGCEDMTFHQFWQAYEDIIRKARGNALTADDFAGTTISLTNPGPSGTNHSVPRLTKGQSAIIGVGAMDYPAEFQGASEKTLVDMGISKIVTLTSTYDHRVIQGAESGDFLRKMHQLLLGEDGFFDDIFASLRIPYEPVRWTQDIPEGAVDKTARVLELIDAYRTRGHLMADIDPLNYRQRRHEDLDVLSHSLTLWDLDREFAVGGFAGKEHLKLRDVLGVLRDSYCRTVGVEYMHILEPDEREWLQQRVEKPHTKPEPSEQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAETVVPLLDAVLDTSAAHELDEVVIGMPHRGRLNVLANIVGKPISQIFREFEGNLDPGQAHGSGDVKYHLGAEGKYFRMFGDGETKVSLTSNPSHLEAVDPVLEGIVRAKQDILDKGQEGFTVLPVLLHGDAAFAGQGVVAETLNLSLLRGYRTGGTVHVIVNNQVGYTTAPEHSRSSKYCTDVAKMIGAPVFHVNGDDPEACVWVAKLAVAYRQAFGKDVVIDMVCYRRRGHNEGDDPSMTQPKIYDAIDKMRSVRKVYTEALIGRGDITVEEAEKALKDYAAQLEHVFNEVRELEKHPPAPSPSVESEQQVPRGLTTAIPRETVERIADSHINLPEGFTPHPRVKPVLERRAKMGREGGIDWAFGELLAFGSLVMEGRQVRLTGQDSRRGTFVQRHSVLIDRKDNSEFTPLQNLSDDQAKFLVYDSALSEFAAVGFEYGYSVGNPDSLVLWEAQFGDFFNGAQSIIDEFISSGEAKWGQRSDVVMLLPHGHEGQGPDHTSGRIERWLQLCAEGSMTVAMPSTPANYFHLLRRHALDGIHRPLVVFTPKSMLRLKAATSPVEDFTEGKFTSVIDDLAQPDPAAVRNVVLCTGKLYYELAAHRDKHGITDTAIVRLEQLYPLPHRKLGALFERYPNATSIRWTQEEPANQGAWPFLGLALPELFPQLVGKLQRVSRRPMAAPATGLAKVHEVEQAEVVQNAFA
>NZ_CP040605.1|WP_010304877.1|1515668_1515845_+|hypothetical-protein
MYFTDRGIEELEDRRGDDEVTLAWVADRMRAFVDLNPDFEDATERLATFLARDDADDE
>NZ_CP040605.1|WP_168584080.1|1516609_1516915_+|hypothetical-protein
MRRLLAGALLTGLAVLGAAGTAAASDAPRPSTPDQILAEIAGAVGGPQGPTKHGQVSVNEQHKYQKTQQHHTQSSTQHGQQHSRSSTQQAQTLQGGSSWKG
>NZ_CP040605.1|WP_168585212.1|1517069_1518110_+|L-threonine-3-dehydrogenase
MRALVKTTPAPGLELTELPDPAPGPDEVVVRVMRTGICGTDLHIASWDEWAARTVPTPLVVGHEFAGEVVATGAAVTRAAVGDFVSGEGHLVCGRCRNCLAGRRHLCAHTEGLGVHRNGAFAEFAVLPEQNVWVHRGEVDPDVAAIFDPFGNAVHTALSFPVVGEDVLITGAGPIGLMAASVARHAGARHVVITDVSEHRLELARRVGVDLAVDVSQARVADAHQQLGLSEGFDVAMEVSGKPEALREVVANMAHGGRIAMLGLPAEDFSLDWSAVVFKMLTVKGIYGREMFATWYSMSVLLESGLDLMPVITHRFPYTEHAEAFETARSGRCGKVILDWTTKGSA
>NZ_CP040605.1|WP_168585213.1|1518109_1519297_+|glycine-C-acetyltransferase
MYTIADDVRAELAEIRAAGLYKDERVLDSPQSARVGVGGAELLNFCANNYLGLADHPALLAAAEEALAKWGFGMASVRFICGTQAPHKELERRLSGFLGTDDTILYSSCFDANGGVFETLLDDRDAVISDELNHASIIDGIRLSKARRGRYRNRDMADLERLLQENTDARRKLVVTDGVFSMDGYLAPLDEICALAEKYGALVMVDDSHAVGFTGPTGAGTPELFGVSDRVDVVTGTLGKALGGASGGYVSGRAEIVELLRQRSRPYLFSNSLAPSIVAASLAALDLVAAQPELRERLRHNSALFRRRMAEEGFDLLPGEHPIIPVMIGDAAEAARMADLLLGEGVYVIGFSYPVVPVGKARIRTQMSAAHRADDVESAVSAFVAARERMGIIAR
>NZ_CP040605.1|WP_168585214.1|1519293_1520208_+|LysR-family-transcriptional-regulator
MIDPRRLLVLRALADHGTVRAAAEKLYLTPSAVSQQLTALENEVGQSLLARQGRRVRLTAAGELLVEHAKAVLAELERAEASLAACAAGTVGTVEVASFASAITQVVAPSIVVLRQRAPDVRVLVRDAEAHNSLMMLLAGEIDIAISMEYTSTLQADARRVSRFPLYTEPFDVVLPPQHRLSAADAVALDELRDDDWIAPLPGNPCRAVAQVCCENAGFVPNITHTSDDFHAVVALVAAGTGVALVPRTAIAGDQGVVALPVAGRPPTRRVFAAVQCGREDHPLVRVVLDALLANKERGTIRPS
>NZ_CP040605.1|WP_168585215.1|1520614_1521772_-|imidazolonepropionase
MTGTVITGIGELVTNDDELGTLTDAALVIDRDRVVWAGPAASAPDADERFHAAGRAVLPGWVDSHTHLVFAGDRTAEFAARMAGKPYQAGGIAVTVGATRGATDEELAANLRKHIAEAAAQGTTCMETKTGYGLTVADELRSAKIAAEADEVTFLGAHLVPPGEDADAYVDLVCGKMLDAVAPHVGWCDVFCEKGAFDVDQSTRILEAAKERGLGLRVHGNQLAPGPGVRLAVEMGAASVDHCTYLAESDVDALAGSETVATLLPACDLSTRQPLPDARALIDAGATVALASNCNPGSSYTSSMAFCVTTAVLQMRMSIEEAVRAATWGGARALRRESGDGAVGVLRPGARADVHILDAPSTTWLAYRPGVPLTHAVWRRGNRIR
>NZ_CP040605.1|WP_168585216.1|1521807_1523124_-|formimidoylglutamate-deiminase
MATYWCEWAWLPGGPERGVLFEVDGGRISAAGPARTPPEHSERLPGMTLPGLANAHSHAFHRALRGRHNGARGTFWTWRDQMYQVAAVLDPDSYYRLARGVYAEMALAGITCVGEFHYVHHAASGTRYDDPNAMGHALVQAAQDAGIRLTLLDTCYLAGGFGRPLDGVQRRFSDGAATSWSDRIDQYIMDRDRVRLGAALHSVRAVPAEEIPEVAGWARKSEAPLHLHLSERRAENEACLAAHGCTPTQLLESHGALGADVTAVHATHLAASDVALLGGSGTGVCLCPTTEADLADGIGPAAALRVAGSTLAIGSDGHSVIDPFAEAQAVESYSRLNTETRGHFAADELLEMATTAGHRSLGWPDAGWLGVGARADFVAVDLGSTRLAGVAPEAVPAVARADDVRVVIADGRRIVQDGRHQAIDAAGELHDAISALRA
>NZ_CP040605.1|WP_168589856.1|1523129_1524311_-|allantoate-amidohydrolase
MAAIADVGADRRRGGYSRHVFDDAERELREWFVEQAEARDLRVTTDRNANIWAWWGEPGDDAVVTGSHLDSVPGGGAFDGPLGVVSSLSSVDLLRAKGFTPRKPLAVVVFAEEEGGRFGVPCLGSSLLAGTIDADRARALRDPNGVTFAEAMSSFGADPARLGRDEEALRRIGQFVELHVEQGRGLIDLGRPVAVASSILAHGRWRFRFGGQGNHAGATLIADRHDPMLPASRLILEARRIAEGVDGGRATVGRLVPNPGGSNVIASTVDVWLDARSPDDRSTRSIVEDLSGAAGEFAAAEGCQVEVVEESYGDNVHFDTAFRDQLSGLLDDAPALPTGAGHDAGILAAEVPTAMLFVRNPTGISHAPEEHAEPDDCDSGAHALARVLENLAG

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Crispr_ID: NZ_CP040605_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_7

1510971-1511212

Orphan

Consensus_repeat	Method
GTGAGCAAGGGAACCTTCCTGTCAT	CRISPRCasFinder
GAGGAAGGGAACCTTCCTGTCA	PILER-CR
AAGGGAACCTTCCTGTCA	CRT

4 spacers

The CRISPR arrays of NZ_CP040605_7

>merge|NZ_CP040605|7|1510971-1511212|CRISPRCasFinder,PILER-CR,CRT
GTGAGCAAGGGAACCTTCCTGTCATCCACCGCATCTGCCGGGCCCATGTGATGTGAGGAAGGGAACCTTCCTGTCATTCCACGCCCCAGCGGCTCGGCGTGGTGCCGGAGTGGAGCAAGGGAACCTTCCTGTCACCGACGGGGCGCGCGAGCATGGGTCCTGACGTGAGGAAGGGAACCTTCCTGTCATCCGCAGCCCGGCACAGGCGTTGCTGGGGTGGTGGAAGGGAACCTTCCTGTCAC

>NZ_CP040605|7|6|1510971-1511212|CRISPRCasFinder
GTGAGCAAGGGAACCTTCCTGTCAT	CCACCGCATCTGCCGGGCCCATGTGAT
GTGAGGAAGGGAACCTTCCTGTCAT	TCCACGCCCCAGCGGCTCGGCGTGGTGCCGGAG
TGGAGCAAGGGAACCTTCCTGTCAC	CGACGGGGCGCGCGAGCATGGGTCCTGAC
GTGAGGAAGGGAACCTTCCTGTCAT	CCGCAGCCCGGCACAGGCGTTGCTGGGG
TGGTGGAAGGGAACCTTCCTGTCAC

>NZ_CP040605|7|2|1510973-1511211|PILER-CR
GAGCAAGGGAACCTTCCTGTCA	TCCACCGCATCTGCCGGGCCCATGTGATGT
GAGGAAGGGAACCTTCCTGTCA	TTCCACGCCCCAGCGGCTCGGCGTGGTGCCGGAGTG
GAGCAAGGGAACCTTCCTGTCA	CCGACGGGGCGCGCGAGCATGGGTCCTGACGT
GAGGAAGGGAACCTTCCTGTCA	TCCGCAGCCCGGCACAGGCGTTGCTGGGGTG
GTGGAAGGGAACCTTCCTGTCA

>NZ_CP040605|7|1|1510977-1511211|CRT
AAGGGAACCTTCCTGTCA	TCCACCGCATCTGCCGGGCCCATGTGATGTGAGG
AAGGGAACCTTCCTGTCA	TTCCACGCCCCAGCGGCTCGGCGTGGTGCCGGAGTGGAGC
AAGGGAACCTTCCTGTCA	CCGACGGGGCGCGCGAGCATGGGTCCTGACGTGAGG
AAGGGAACCTTCCTGTCA	TCCGCAGCCCGGCACAGGCGTTGCTGGGGTGGTGG
AAGGGAACCTTCCTGTCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168585205.1\|1500965_1502522_+\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379258
NZ_CP040605.1\|WP_168585217.1\|1524442_1526095_-\|urocanate-hydratase	unknown	unknown	gnl\|CDD\|235448
NZ_CP040605.1\|WP_168585207.1\|1504412_1504640_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168585214.1\|1519293_1520208_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176115
NZ_CP040605.1\|WP_168585204.1\|1500226_1500598_-\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_CP040605.1\|WP_168585215.1\|1520614_1521772_-\|imidazolonepropionase	unknown	unknown	gnl\|CDD\|237604
NZ_CP040605.1\|WP_168585213.1\|1518109_1519297_+\|glycine-C-acetyltransferase	unknown	unknown	gnl\|CDD\|235893
NZ_CP040605.1\|WP_168585210.1\|1507289_1510964_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP040605.1\|WP_168585211.1\|1511656_1515334_+\|multifunctional-oxoglutarate-decarboxylase/oxoglutarate-dehydrogenase-thiamine-pyrophosphate-binding-subunit/dihydrolipoyllysine-residue-succinyltransferase-subunit	unknown	unknown	gnl\|CDD\|237030
NZ_CP040605.1\|WP_168585201.1\|1496870_1497722_+\|NmrA-family-NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|187578
NZ_CP040605.1\|WP_168585212.1\|1517069_1518110_+\|L-threonine-3-dehydrogenase	unknown	unknown	gnl\|CDD\|180054
NZ_CP040605.1\|WP_168585208.1\|1505102_1506071_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213235
NZ_CP040605.1\|WP_010304877.1\|1515668_1515845_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168585216.1\|1521807_1523124_-\|formimidoylglutamate-deiminase	unknown	unknown	gnl\|CDD\|236420
NZ_CP040605.1\|WP_168589856.1\|1523129_1524311_-\|allantoate-amidohydrolase	unknown	unknown	gnl\|CDD\|236456
NZ_CP040605.1\|WP_168585209.1\|1506070_1506925_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|372253
NZ_CP040605.1\|WP_168584080.1\|1516609_1516915_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239487
NZ_CP040605.1\|WP_168585202.1\|1497738_1498614_+\|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223528
NZ_CP040605.1\|WP_168585206.1\|1502837_1503953_+\|alanine-dehydrogenase	unknown	unknown	gnl\|CDD\|240630
NZ_CP040605.1\|WP_168585203.1\|1498843_1500199_-\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|273233

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168585205.1\|1500965_1502522_+\|PucR-family-transcriptional-regulator	gnl\|CDD\|379258	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain. This helix-turn-helix domain is often found at the C-terminus of PucR-like transcriptional regulators such as Bacillus subtilis pucR and is likely to be DNA-binding.	9.45118e-16
NZ_CP040605.1\|WP_168585217.1\|1524442_1526095_-\|urocanate-hydratase	gnl\|CDD\|235448	PRK05414, PRK05414, urocanate hydratase; Provisional.	0
NZ_CP040605.1\|WP_168585214.1\|1519293_1520208_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176115	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.27803e-55
NZ_CP040605.1\|WP_168585204.1\|1500226_1500598_-\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	5.71611e-58
NZ_CP040605.1\|WP_168585215.1\|1520614_1521772_-\|imidazolonepropionase	gnl\|CDD\|237604	PRK14085, PRK14085, imidazolonepropionase; Provisional.	0
NZ_CP040605.1\|WP_168585213.1\|1518109_1519297_+\|glycine-C-acetyltransferase	gnl\|CDD\|235893	PRK06939, PRK06939, 2-amino-3-ketobutyrate coenzyme A ligase; Provisional.	0
NZ_CP040605.1\|WP_168584080.1\|1516609_1516915_+\|hypothetical-protein	gnl\|CDD\|239487	cd03393, PAP2_like_3, PAP2_like_3 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria and archaea, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	0.00232224
NZ_CP040605.1\|WP_168585211.1\|1511656_1515334_+\|multifunctional-oxoglutarate-decarboxylase/oxoglutarate-dehydrogenase-thiamine-pyrophosphate-binding-subunit/dihydrolipoyllysine-residue-succinyltransferase-subunit	gnl\|CDD\|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0
NZ_CP040605.1\|WP_168585201.1\|1496870_1497722_+\|NmrA-family-NAD(P)-binding-protein	gnl\|CDD\|187578	cd05269, TMR_SDR_a, triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs. TMR is an atypical NADP-binding protein of the SDR family. It lacks the active site residues of the SDRs but has a glycine rich NAD(P)-binding motif that matches the extended SDRs. Proteins in this subgroup however, are more similar in length to the classical SDRs. TMR was identified as a reducer of triphenylmethane dyes, important environmental pollutants. This subgroup also includes Escherichia coli NADPH-dependent quinine oxidoreductase (QOR2), which catalyzes two-electron reduction of quinone; but is unlikely to play a major role in protecting against quinone cytotoxicity. Atypical SDRs are distinct from classical SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.82545e-70
NZ_CP040605.1\|WP_168585212.1\|1517069_1518110_+\|L-threonine-3-dehydrogenase	gnl\|CDD\|180054	PRK05396, tdh, L-threonine 3-dehydrogenase; Validated.	0
NZ_CP040605.1\|WP_168585208.1\|1505102_1506071_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213235	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter. The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.	3.77938e-92
NZ_CP040605.1\|WP_168585216.1\|1521807_1523124_-\|formimidoylglutamate-deiminase	gnl\|CDD\|236420	PRK09229, PRK09229, N-formimino-L-glutamate deiminase; Validated.	2.15187e-169
NZ_CP040605.1\|WP_168589856.1\|1523129_1524311_-\|allantoate-amidohydrolase	gnl\|CDD\|236456	PRK09290, PRK09290, allantoate amidohydrolase; Reviewed.	2.59561e-164
NZ_CP040605.1\|WP_168585210.1\|1507289_1510964_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.3807e-157
NZ_CP040605.1\|WP_168585209.1\|1506070_1506925_+\|ABC-transporter-permease-subunit	gnl\|CDD\|372253	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family.	9.79724e-06
NZ_CP040605.1\|WP_168585202.1\|1497738_1498614_+\|NAD(P)-dependent-oxidoreductase	gnl\|CDD\|223528	COG0451, WcaG, Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	2.69285e-23
NZ_CP040605.1\|WP_168585206.1\|1502837_1503953_+\|alanine-dehydrogenase	gnl\|CDD\|240630	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains. Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.	0
NZ_CP040605.1\|WP_168585203.1\|1498843_1500199_-\|L-serine-ammonia-lyase	gnl\|CDD\|273233	TIGR00720, hypothetical_protein_NEICINOT_00681, L-serine dehydratase, iron-sulfur-dependent, single chain form. This enzyme is also called serine deaminase and L-serine dehydratase 1. L-serine ammonia-lyase converts serine into pyruvate in the gluconeogenesis pathway from serine. This enzyme is comprised of a single chain in Escherichia coli, Mycobacterium tuberculosis, and several other species, but has separate alpha and beta chains in Bacillus subtilis and related species. The beta and alpha chains are homologous to the N-terminal and C-terminal regions, respectively, but are rather deeply branched in a UPGMA tree. This enzyme requires iron and dithiothreitol for activation in vitro, and is a predicted 4Fe-4S protein. Escherichia coli Pseudomonas aeruginosa have two copies of this protein. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	0

>NZ_CP040605.1|WP_168585210.1|1507289_1510964_+|ABC-transporter-ATP-binding-protein
MGASVTAVGLEALVPLLTKAAVDDAVAHSTDRLLWIVIALLTLGVFRFASAFVRRYSAGRLALDVQHDLRRAVFAAMQRLDGGKQDALRTGQVVSRSISDLQMVNSLLSMLPLAAGTAVLALFAIVVMLWLSPLLTVVSLVVAPLIAVVSARSKKSLFPATWSAQQRAADIAQHVEETVTGVRVVKGFGQEDREVGRLERRARRLFGERLRAARMTSMPAASLAALPSAGQVGVLGLGGWMVLQDQVSLGTFVAFAGYVAMLAGPARMLSSVMIQAQLARAGVERIHELIDSQPEVQEKPGAATLPEGPLQVRLDDASFGYTRDQPVLCNASLQVRPGETVALVGPAGSGKSTVSLLLPRFYDLHSGSIKIGPADDGSVSHDIRDLRLDSLRAAVGLVFEEAFLFSDTIRGNIAYGRPDASEADVIAAAKAAEAHEFISTLPDGYDTTVGERGLTLSGGQRQRVALARALLSNPRILVLDDATSAVDPATEAAIHDTLRLVTAQRTTLLIAHRRSTLALADRIAVLDEGHVVDIGTEDELNQRCELFRSLLAGPGELIDNRCDGRVVPGSEGITPELWPPEDDAEPAVTGNAATTPGSRGMGGMTMPPTPELIEGIRKLPPATDQPDLRGEDPTAPDPDFKLPRLLRPIRWGLLLTALLVAGDALTSIALPSLVRQGIDGGVSAGDLDALWIATGLGAVIVAGGWLVVKLQTVITSRTGETLLYLLRLRSFAHLQRLGLDYYERELAGRIMTRMTTDVDALSTFLQTGLATFVVSVLTLFGIAGALLITDVSLALVAMAVLPVLLVATLIFRKVSATAYAEARERVSTVNADLQENVAGMRVAQAHRREGHAAKVFAQRSDAYRRSRLRAQRYIATYFPFVALLSEIAQAVVLGVGAARVASGDLTAGVLVAFLLYLGLFFSPVQQLSGVFDGYQQAKVGLRRIGELLRTPTSVPAATDPTPVPERFEGGIELRSVSFRYPGTDQFALRDIALRVRPGETVALVGATGAGKSTLIKLIARFYDATDGAVLVDGQDIRSYDLAAFHRRLAVVPQEGHLFTGDIATNIAYARPDADPAEVEAAARAVGALPGIAMLPRGFRQQVGERGRGLSAGQRQLVALARAELVDPDVLLLDEATAALDPATESMVVAASDQVAAQRTTFVVAHRLATAARADRIVVVDGGRIVEQGSHAELLADNSYYARLWRAADGAPSEETPEIGETNIA
>NZ_CP040605.1|WP_168585209.1|1506070_1506925_+|ABC-transporter-permease-subunit
MGGLVKAEFRKIFSTSLWWALLIPVALLGFGAGWLGSSIVALIDAVEQFDRAVPLGLLSVSMSTNFSTIFAALFGAMAFAGEFRNKSITTTYLTSNPRSAVLAAKLIACSGVGLIYGLANVLFASVGGLVGAGRDFGGFGSLGDWLSVGAAAVLAMVLWTLLGVGFGALVANAVLAIIVPLVYKFMVEFILSLSLIESPAAGISPYLPGTAGNGIVANLAVPLFVTAVAGPDEPNTPRAAFEFLHLFFGGSYGHPWWASLLTFLGYAAVFIAGGWLVSRRRDIS
>NZ_CP040605.1|WP_168585208.1|1505102_1506071_+|ABC-transporter-ATP-binding-protein
MHDGSGRLIVQGLSKSFGPVNAVQDLNFTVRPGSVTGFLGPNGSGKTTTLRMLLGLVTPTAGTATINGLPFHQLPNPATVVGAVLDAQSFHPGRTARQHLRCYAAAMNVPDAQVDRALELVGLSAAAKRKAGTFSLGMRQRLALATALLGDPQVLVLDEPANGLDPEGIAWLRNFLKAFAASGRTVLMSSHFLREIEHTVDQLVIISRGRCVFDGHLDQLRAAQRSRALVQAADPSKLVDKLQEAGYSIEYLPDGRIAVTGSDSRAVADLALEAGIALYGMQDERIGLEQLFFQLTNGQYNGVQQHGAQWSAPGGQGFGGNA
>NZ_CP040605.1|WP_168585207.1|1504412_1504640_+|hypothetical-protein
MRRAVLDQLDGVDLTTADDTPEVLLPLARTQLYLLTSYYLLTSAPCSTNTIRTRPAGAAPARARRAAGRGRAPCG
>NZ_CP040605.1|WP_168585206.1|1502837_1503953_+|alanine-dehydrogenase
MKIAVPREIKNNEYRVAITPAGVHELTTRGHDVFVETNAGAGSSIPDEDYLAAGAKVLPTAEEVWAEGQLVLKVKEPIAEEYPRLRRDQVLFTYLHLAASAELTDAMLKSGVTGIAYETVQTANGSLPLLAPMSEVAGRLAPQVGAYSLMRPSGGRGVLPGGVPGVHPARVVVIGGGVAGLNAARVAMGMGADVELLDTNVDKLREIDRDFHGQIRTVTSNRYSVEQAVRAADLVIGAVLIPGAKAPKLVSNHLVSEMKQGSVLVDIAIDQGGCFADSRPTTHDDPTYRVHNSVFYCVANMPGAVPNTSTHALTNVTLPYVLRIADQGWQQACRADAALAGGLNTHDCKLVNEPVAEAHGLTSTPLSSVLG
>NZ_CP040605.1|WP_168585205.1|1500965_1502522_+|PucR-family-transcriptional-regulator
MLDIRALVERVGPTLLRTVVAPEPRVCVGDVVIAEPDEPPTAAGGDLVLGVAIPDREHAVALTRDCGAKGAAAVLLKPPISADDAVAAAARDAGVALVEVRPGTAWAQLVWLIRAALAGTDIEEADAPSTGVGDLFRLADAVADVVDAPVTIEDARSQVLAYSARQDLTDPARVSTIMGRRQPDDVLAKFRARGTFRQLSKGSSAIFVPAQQDGTLPRLVVPIRMGGELLGSMWAVVPGEVSEERSTAFADTAPLVALQLLRWRAVADAERRRSAEQVRLLLEGGEGWRAAANELAVPAEAHRVVAIEMPPSASPAEGHRLAMWEWITRGIGRRPLVTEIGTMLYALVPDRGRAGGWPDLRAALTSHDVSPRPLIAVGTAVAVAELPQSRSQAEELISLLRTGQLQQRVAVYEENWHLLVLSRMAGAATDAGIGALGPLPVLREHDRTQGTEYLATLHAWLRHPGDPRQASRELRVHPNTFRYRMKRLTQLVDVDLEDPNVRSALFAQLLADRWAQHG
>NZ_CP040605.1|WP_168585204.1|1500226_1500598_-|glycine-cleavage-system-protein-GcvH
MSLPAHLRYSEEHEWIEDRDELVRIGITQHAADALGDIVYVQLPEVGDKIEAGQACGELESTKSVSDLFAPVTGEVVALNESVVDDPALLNAEPFGDGWLLEVRPTSTGSLLTAEQYAELIAE
>NZ_CP040605.1|WP_168585203.1|1498843_1500199_-|L-serine-ammonia-lyase
MAISVFDLFSVGIGPSSSHTVGPMRAARLFVQRLHSAGRLPQVERIKAELFGSLGATGHGHGSPKAVLLGLEGHSPETVDPAAVEGRVTEIRDSGRLRLDGVQQIRFIVDRDLVMHRRKSLPLHPNGMRFAAFGADDAELDSAVFYSVGGGFVVDEDATGTDRIKPDETAVRYPFRTGVELLARTEQSGLPISGVMLANELSWRGEDAVHKELLGIWQVMRECVDNGCRNSGELPGGLKVRRRAAELAASLTERDDPLEWVTLFALAVNEENAAGGRVVTAPTNGAAGIVPAVLHYYTRFAPGADDAGVVRFLLAAGAVGVLFKENASISGAEVGCQGEVGSACSMAAAGLAEVLGGTPRQVENAAEIAMEHNLGLTCDPIGGLVQIPCIERNAVASVKAITAARMALRGDGSHFVSLDKVIKTMRETGRDMKVKYKETARGGLAVNVIEC
>NZ_CP040605.1|WP_168585202.1|1497738_1498614_+|NAD(P)-dependent-oxidoreductase
MHVFAIGASGVLGRHLVPMLLRRGHDVTVMAPDRLDRLPGEARRVRASLLDPAAERLLAAEFKEVDAVVNAATAVPAMPTAPGGWARNTALRSTGTAVVTGALQEAEVRRFVQMSITMVYADGGDDKLTEAAPLDHRPERATLVDPVLAMETAVRKLPADEIAWSILRGGRFVGPGTVQDQQRARLRAEDLPIPGAGREWVSMVHARDYADAVVAALERGCAGKTLNVADQPVRVADYYRDLARADDSPPPRHDPNAAAEPSHRVSSEAARQLLGWAPVHGIWPLGDDEDR
>NZ_CP040605.1|WP_168585201.1|1496870_1497722_+|NmrA-family-NAD(P)-binding-protein
MTLTVAGASGVVGRAVTRELVRLGHRPRVLVRPGSPNRDLSPDATVVECDLTDRAATLRALHGSERLFLLTPFHSEQLVLQRNLIAASAEAGVKRVVKLSALGARPGAESSIHHQHGVGDDELRASGLPHAVLRPNAFMQNALQWLPTIRRRDAIVLPVGAARVSMIDVGDIGLAAVTLLTSDAVGDYDLTGPEALSYREVASILSEVAGRRIRHVDAEPAEVAAAMRSAGVPDWAVAARLQLYATYRAGDAEVVTTAINDITGRPPRDYRSFAAGLAEQLRN
>NZ_CP040605.1|WP_168585211.1|1511656_1515334_+|multifunctional-oxoglutarate-decarboxylase/oxoglutarate-dehydrogenase-thiamine-pyrophosphate-binding-subunit/dihydrolipoyllysine-residue-succinyltransferase-subunit
MSSSPASQFGPNEWLIEEMYEQFLQDPTSVDSAWHEFFADYKPGQAAIENTAAAAAAAAAPTTTATVTRPSETNGQAPPAAATTAPPASKPAPKPSPQQAARAAPVKEPQAGGDVKTLRGAAAAIAKNMDQSLTVPTATSVRAVPAKLLFDNRIVINNHLKRNKGGKVSFTHLIGYALVRAVRDFPNMNRHYGEDAKGKPAAVTPEHINLGLAIDLPAKDGSRNLVVASIKGCEDMTFHQFWQAYEDIIRKARGNALTADDFAGTTISLTNPGPSGTNHSVPRLTKGQSAIIGVGAMDYPAEFQGASEKTLVDMGISKIVTLTSTYDHRVIQGAESGDFLRKMHQLLLGEDGFFDDIFASLRIPYEPVRWTQDIPEGAVDKTARVLELIDAYRTRGHLMADIDPLNYRQRRHEDLDVLSHSLTLWDLDREFAVGGFAGKEHLKLRDVLGVLRDSYCRTVGVEYMHILEPDEREWLQQRVEKPHTKPEPSEQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAETVVPLLDAVLDTSAAHELDEVVIGMPHRGRLNVLANIVGKPISQIFREFEGNLDPGQAHGSGDVKYHLGAEGKYFRMFGDGETKVSLTSNPSHLEAVDPVLEGIVRAKQDILDKGQEGFTVLPVLLHGDAAFAGQGVVAETLNLSLLRGYRTGGTVHVIVNNQVGYTTAPEHSRSSKYCTDVAKMIGAPVFHVNGDDPEACVWVAKLAVAYRQAFGKDVVIDMVCYRRRGHNEGDDPSMTQPKIYDAIDKMRSVRKVYTEALIGRGDITVEEAEKALKDYAAQLEHVFNEVRELEKHPPAPSPSVESEQQVPRGLTTAIPRETVERIADSHINLPEGFTPHPRVKPVLERRAKMGREGGIDWAFGELLAFGSLVMEGRQVRLTGQDSRRGTFVQRHSVLIDRKDNSEFTPLQNLSDDQAKFLVYDSALSEFAAVGFEYGYSVGNPDSLVLWEAQFGDFFNGAQSIIDEFISSGEAKWGQRSDVVMLLPHGHEGQGPDHTSGRIERWLQLCAEGSMTVAMPSTPANYFHLLRRHALDGIHRPLVVFTPKSMLRLKAATSPVEDFTEGKFTSVIDDLAQPDPAAVRNVVLCTGKLYYELAAHRDKHGITDTAIVRLEQLYPLPHRKLGALFERYPNATSIRWTQEEPANQGAWPFLGLALPELFPQLVGKLQRVSRRPMAAPATGLAKVHEVEQAEVVQNAFA
>NZ_CP040605.1|WP_010304877.1|1515668_1515845_+|hypothetical-protein
MYFTDRGIEELEDRRGDDEVTLAWVADRMRAFVDLNPDFEDATERLATFLARDDADDE
>NZ_CP040605.1|WP_168584080.1|1516609_1516915_+|hypothetical-protein
MRRLLAGALLTGLAVLGAAGTAAASDAPRPSTPDQILAEIAGAVGGPQGPTKHGQVSVNEQHKYQKTQQHHTQSSTQHGQQHSRSSTQQAQTLQGGSSWKG
>NZ_CP040605.1|WP_168585212.1|1517069_1518110_+|L-threonine-3-dehydrogenase
MRALVKTTPAPGLELTELPDPAPGPDEVVVRVMRTGICGTDLHIASWDEWAARTVPTPLVVGHEFAGEVVATGAAVTRAAVGDFVSGEGHLVCGRCRNCLAGRRHLCAHTEGLGVHRNGAFAEFAVLPEQNVWVHRGEVDPDVAAIFDPFGNAVHTALSFPVVGEDVLITGAGPIGLMAASVARHAGARHVVITDVSEHRLELARRVGVDLAVDVSQARVADAHQQLGLSEGFDVAMEVSGKPEALREVVANMAHGGRIAMLGLPAEDFSLDWSAVVFKMLTVKGIYGREMFATWYSMSVLLESGLDLMPVITHRFPYTEHAEAFETARSGRCGKVILDWTTKGSA
>NZ_CP040605.1|WP_168585213.1|1518109_1519297_+|glycine-C-acetyltransferase
MYTIADDVRAELAEIRAAGLYKDERVLDSPQSARVGVGGAELLNFCANNYLGLADHPALLAAAEEALAKWGFGMASVRFICGTQAPHKELERRLSGFLGTDDTILYSSCFDANGGVFETLLDDRDAVISDELNHASIIDGIRLSKARRGRYRNRDMADLERLLQENTDARRKLVVTDGVFSMDGYLAPLDEICALAEKYGALVMVDDSHAVGFTGPTGAGTPELFGVSDRVDVVTGTLGKALGGASGGYVSGRAEIVELLRQRSRPYLFSNSLAPSIVAASLAALDLVAAQPELRERLRHNSALFRRRMAEEGFDLLPGEHPIIPVMIGDAAEAARMADLLLGEGVYVIGFSYPVVPVGKARIRTQMSAAHRADDVESAVSAFVAARERMGIIAR
>NZ_CP040605.1|WP_168585214.1|1519293_1520208_+|LysR-family-transcriptional-regulator
MIDPRRLLVLRALADHGTVRAAAEKLYLTPSAVSQQLTALENEVGQSLLARQGRRVRLTAAGELLVEHAKAVLAELERAEASLAACAAGTVGTVEVASFASAITQVVAPSIVVLRQRAPDVRVLVRDAEAHNSLMMLLAGEIDIAISMEYTSTLQADARRVSRFPLYTEPFDVVLPPQHRLSAADAVALDELRDDDWIAPLPGNPCRAVAQVCCENAGFVPNITHTSDDFHAVVALVAAGTGVALVPRTAIAGDQGVVALPVAGRPPTRRVFAAVQCGREDHPLVRVVLDALLANKERGTIRPS
>NZ_CP040605.1|WP_168585215.1|1520614_1521772_-|imidazolonepropionase
MTGTVITGIGELVTNDDELGTLTDAALVIDRDRVVWAGPAASAPDADERFHAAGRAVLPGWVDSHTHLVFAGDRTAEFAARMAGKPYQAGGIAVTVGATRGATDEELAANLRKHIAEAAAQGTTCMETKTGYGLTVADELRSAKIAAEADEVTFLGAHLVPPGEDADAYVDLVCGKMLDAVAPHVGWCDVFCEKGAFDVDQSTRILEAAKERGLGLRVHGNQLAPGPGVRLAVEMGAASVDHCTYLAESDVDALAGSETVATLLPACDLSTRQPLPDARALIDAGATVALASNCNPGSSYTSSMAFCVTTAVLQMRMSIEEAVRAATWGGARALRRESGDGAVGVLRPGARADVHILDAPSTTWLAYRPGVPLTHAVWRRGNRIR
>NZ_CP040605.1|WP_168585216.1|1521807_1523124_-|formimidoylglutamate-deiminase
MATYWCEWAWLPGGPERGVLFEVDGGRISAAGPARTPPEHSERLPGMTLPGLANAHSHAFHRALRGRHNGARGTFWTWRDQMYQVAAVLDPDSYYRLARGVYAEMALAGITCVGEFHYVHHAASGTRYDDPNAMGHALVQAAQDAGIRLTLLDTCYLAGGFGRPLDGVQRRFSDGAATSWSDRIDQYIMDRDRVRLGAALHSVRAVPAEEIPEVAGWARKSEAPLHLHLSERRAENEACLAAHGCTPTQLLESHGALGADVTAVHATHLAASDVALLGGSGTGVCLCPTTEADLADGIGPAAALRVAGSTLAIGSDGHSVIDPFAEAQAVESYSRLNTETRGHFAADELLEMATTAGHRSLGWPDAGWLGVGARADFVAVDLGSTRLAGVAPEAVPAVARADDVRVVIADGRRIVQDGRHQAIDAAGELHDAISALRA
>NZ_CP040605.1|WP_168589856.1|1523129_1524311_-|allantoate-amidohydrolase
MAAIADVGADRRRGGYSRHVFDDAERELREWFVEQAEARDLRVTTDRNANIWAWWGEPGDDAVVTGSHLDSVPGGGAFDGPLGVVSSLSSVDLLRAKGFTPRKPLAVVVFAEEEGGRFGVPCLGSSLLAGTIDADRARALRDPNGVTFAEAMSSFGADPARLGRDEEALRRIGQFVELHVEQGRGLIDLGRPVAVASSILAHGRWRFRFGGQGNHAGATLIADRHDPMLPASRLILEARRIAEGVDGGRATVGRLVPNPGGSNVIASTVDVWLDARSPDDRSTRSIVEDLSGAAGEFAAAEGCQVEVVEESYGDNVHFDTAFRDQLSGLLDDAPALPTGAGHDAGILAAEVPTAMLFVRNPTGISHAPEEHAEPDDCDSGAHALARVLENLAG
>NZ_CP040605.1|WP_168585217.1|1524442_1526095_-|urocanate-hydratase
MSEARPVRAPRGTTLTARSWSTEAPLRMLQNNLDPEVAERPDDLVVYGGTGKAARNWASFDAMVRELTTLREDETLLVQSGKPVGVLQTHEWAPRVLIANSNLVGDWANWTEFRRLDALGLMMYGQMTAGSWIYIGTQGILQGTYETFAAIAARRFGGSLAGTLTITAGLGGMGGAQPLAVTMNDGAALVVECDPERAHRRVRHGYLDEVAGDLDAAIEKAVAAKNDRRAYSVAVIGNAAELLPEMLRRGVPADIVTDQTSAHDPLSYLPLGVDLADWRDCAAKKPDEFTERARDSMAKHVEAMVGFLDGGAEVFDYGNSLRGEAELGGYERAFAYPGFVPAYIRPLFCEGKGPFRWAALSGDPADIAKTDRAILDLFGDDEHLARWIRLAGEKVSFQGLPARICWLGYGERAEAGLRFNEMVASGELEAPLVLGRDHLDCGSVASPYRETEAMADTSDAVADWPLLNALVNTASGATWVSLHHGGGVGMGRSLHAGQVTVADGTELAAQKLARVLTNDPGTGVIRHVDAGYERADEVAAERGIRTPLVG

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Crispr_ID: NZ_CP040605_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_8

1547766-1547896

Orphan

Consensus_repeat	Method
TTCCGCAATTTCAATGGAAATTGGACCTTCGATTTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040605_8

>merge|NZ_CP040605|8|1547766-1547896|CRISPRCasFinder
TTCCGCAATTTCAATGGAAATTGGACCTTCGATTTCAATGGAAATTGCGGATGATCGGCGTGTCGCACCACGACACGCCGACGCCTGTGGACAACTTCCGCAATTTCAATGGAAATTCGACCTTCGATTTC

>NZ_CP040605|8|7|1547766-1547896|CRISPRCasFinder
TTCCGCAATTTCAATGGAAATTGGACCTTCGATTTC	AATGGAAATTGCGGATGATCGGCGTGTCGCACCACGACACGCCGACGCCTGTGGACAAC
TTCCGCAATTTCAATGGAAATTCGACCTTCGATTTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168589860.1\|1546342_1546975_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|131992
NZ_CP040605.1\|WP_168585241.1\|1555381_1555555_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168585234.1\|1547274_1547751_+\|Cys-tRNA(Pro)-deacylase	unknown	unknown	gnl\|CDD\|237976
NZ_CP040605.1\|WP_168585231.1\|1543939_1545433_-\|PAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|378836
NZ_CP040605.1\|WP_010304783.1\|1543399_1543654_+\|WhiB-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|376791
NZ_CP040605.1\|WP_168585237.1\|1549293_1550058_-\|SOS-response-associated-peptidase	unknown	unknown	gnl\|CDD\|376837
NZ_CP040605.1\|WP_168584345.1\|1553739_1555179_+\|transposase	unknown	unknown	gnl\|CDD\|379252
NZ_CP040605.1\|WP_168585235.1\|1547930_1548542_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|226101
NZ_CP040605.1\|WP_168585232.1\|1545463_1545679_-\|biotin/lipoyl-binding-carrier-protein	unknown	unknown	gnl\|CDD\|180306
NZ_CP040605.1\|WP_168585229.1\|1540886_1541354_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP040605.1\|WP_168585239.1\|1551553_1552564_+\|ribosome-small-subunit-dependent-GTPase-A	unknown	unknown	gnl\|CDD\|224084
NZ_CP040605.1\|WP_168585230.1\|1542224_1543151_+\|diacylglycerol-kinase-family-lipid-kinase	unknown	unknown	gnl\|CDD\|224513
NZ_CP040605.1\|WP_168585233.1\|1546013_1546346_-\|mycothiol-system-anti-sigma-R-factor	unknown	unknown	gnl\|CDD\|274904
NZ_CP040605.1\|WP_168585238.1\|1550265_1551534_+\|3-phosphoshikimate-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|235037
NZ_CP040605.1\|WP_168585236.1\|1548538_1549255_-\|SOS-response-associated-peptidase	unknown	unknown	gnl\|CDD\|376837
NZ_CP040605.1\|WP_168585242.1\|1555647_1556151_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168585240.1\|1552722_1553583_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168589859.1\|1541363_1541795_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168585243.1\|1556147_1557581_-\|wax-ester/triacylglycerol-synthase-family-O-acyltransferase	unknown	unknown	gnl\|CDD\|274360
NZ_CP040605.1\|WP_168585228.1\|1540215_1540812_+\|acid-phosphatase	unknown	unknown	gnl\|CDD\|139587

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168589860.1\|1546342_1546975_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|131992	TIGR02947, putative_RNA_polymerase_sigma_factor, RNA polymerase sigma-70 factor, TIGR02947 family. This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building, bidirectional best hits and (with the exception of a paralog in Thermobifida fusca YX) one-to-a-genome distribution, to represent a conserved family. This family is restricted to the Actinobacteria and each gene examined is followed by an anti-sigma factor in an apparent operon.	1.3564e-106
NZ_CP040605.1\|WP_168585234.1\|1547274_1547751_+\|Cys-tRNA(Pro)-deacylase	gnl\|CDD\|237976	cd00002, YbaK_deacylase, This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS) inserted (INS) editing domain. The bacterial amino acid trans-editing enzyme YbaK is a deacylase that hydrolyzes cysteinyl-tRNA(Pro)'s mischarged by prolyl-tRNA synthetase. YbaK also hydrolyzes glycyl-tRNA's, alanyl-tRNA's, seryl-tRNA's, and prolyl-tRNA's. YbaK is homologous to the INS domain of prolyl-tRNA synthetase (ProRS) as well as the trans-editing enzyme ProX of Aeropyrum pernix which hydrolyzes alanyl-tRNA's and glycyl-tRNA's.	1.10784e-75
NZ_CP040605.1\|WP_168585231.1\|1543939_1545433_-\|PAS-domain-containing-protein	gnl\|CDD\|378836	pfam12282, H_kinase_N, Signal transduction histidine kinase. This domain is found in bacteria. This domain is about 150 amino acids in length. This domain is found associated with pfam07568, pfam08448, pfam02518. This domain has a single completely conserved residue P that may be functionally important. This family is mostly annotated as a histidine kinase involved in signal transduction but there is little published evidence to support this.	5.87985e-59
NZ_CP040605.1\|WP_010304783.1\|1543399_1543654_+\|WhiB-family-transcriptional-regulator	gnl\|CDD\|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	1.3626e-28
NZ_CP040605.1\|WP_168585237.1\|1549293_1550058_-\|SOS-response-associated-peptidase	gnl\|CDD\|376837	pfam02586, SRAP, SOS response associated peptidase (SRAP). The SRAP family functions as a DNA-associated autoproteolytic switch that recruits diverse repair enzymes onto DNA damage. We propose that the human protein Q96FZ2:UniProtKB, the eukaryotic member of the SRAP family, which has been recently shown to bind specifically to DNA with 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxycytosine, is a sensor for these oxidized bases generated by the TET (tetrahedral aminopeptidase of the M42 family) enzymes from methylcytosine. Hence, its autoproteolytic activity might help it act as a switch that recruits DNA repair enzymes to remove these oxidized methylcytosine species as part of the DNA demethylation pathway downstream of the TET enzymes.	4.29038e-97
NZ_CP040605.1\|WP_168584345.1\|1553739_1555179_+\|transposase	gnl\|CDD\|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	7.65887e-45
NZ_CP040605.1\|WP_168585235.1\|1547930_1548542_-\|alpha/beta-hydrolase	gnl\|CDD\|226101	COG3571, COG3571, Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only].	2.5976e-28
NZ_CP040605.1\|WP_168585232.1\|1545463_1545679_-\|biotin/lipoyl-binding-carrier-protein	gnl\|CDD\|180306	PRK05889, PRK05889, biotin/lipoyl-binding carrier protein.	5.47699e-20
NZ_CP040605.1\|WP_168585229.1\|1540886_1541354_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	8.06235e-17
NZ_CP040605.1\|WP_168585239.1\|1551553_1552564_+\|ribosome-small-subunit-dependent-GTPase-A	gnl\|CDD\|224084	COG1162, COG1162, Predicted GTPases [General function prediction only].	2.52344e-85
NZ_CP040605.1\|WP_168585230.1\|1542224_1543151_+\|diacylglycerol-kinase-family-lipid-kinase	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	4.18122e-53
NZ_CP040605.1\|WP_168585233.1\|1546013_1546346_-\|mycothiol-system-anti-sigma-R-factor	gnl\|CDD\|274904	TIGR03988, antisig_RsrA, mycothiol system anti-sigma-R factor. Members of this family are the anti-sigma-R factor RsrA, which contains a CXXC motif as a thiol-disulphide redox switch. It interacts with sigma-R. It regulates and is regulated by the mycothiol system, which occurs in many actinomycetes. [Transcription, Transcription factors].	8.99306e-29
NZ_CP040605.1\|WP_168585238.1\|1550265_1551534_+\|3-phosphoshikimate-1-carboxyvinyltransferase	gnl\|CDD\|235037	PRK02427, PRK02427, 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional.	1.49725e-173
NZ_CP040605.1\|WP_168585236.1\|1548538_1549255_-\|SOS-response-associated-peptidase	gnl\|CDD\|376837	pfam02586, SRAP, SOS response associated peptidase (SRAP). The SRAP family functions as a DNA-associated autoproteolytic switch that recruits diverse repair enzymes onto DNA damage. We propose that the human protein Q96FZ2:UniProtKB, the eukaryotic member of the SRAP family, which has been recently shown to bind specifically to DNA with 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxycytosine, is a sensor for these oxidized bases generated by the TET (tetrahedral aminopeptidase of the M42 family) enzymes from methylcytosine. Hence, its autoproteolytic activity might help it act as a switch that recruits DNA repair enzymes to remove these oxidized methylcytosine species as part of the DNA demethylation pathway downstream of the TET enzymes.	2.72188e-89
NZ_CP040605.1\|WP_168585243.1\|1556147_1557581_-\|wax-ester/triacylglycerol-synthase-family-O-acyltransferase	gnl\|CDD\|274360	TIGR02946, Putative_diacyglycerol_O-acyltransferase_Mb3115, acyltransferase, WS/DGAT/MGAT. This bacteria-specific protein family includes a characterized, homodimeric, broad specificity acyltransferase from Acinetobacter sp. strain ADP1, active as wax ester synthase, as acyl coenzyme A:diacylglycerol acyltransferase, and as acyl-CoA:monoacylglycerol acyltransferase. [Unknown function, Enzymes of unknown specificity].	2.53424e-149
NZ_CP040605.1\|WP_168585228.1\|1540215_1540812_+\|acid-phosphatase	gnl\|CDD\|139587	PRK13462, PRK13462, acid phosphatase; Provisional.	2.55565e-69

>NZ_CP040605.1|WP_168585234.1|1547274_1547751_+|Cys-tRNA(Pro)-deacylase
MAGKGTPATALLSKRRISHRVHAYEHDPRAESFGLEAAEALGQPPERIFKTLVAEVDGKLTVGVVPVTGQLDLKALAAAVGGKKAKMAEVADAERATGYVAGGISPLGQKKRLPVVIDRSATGFEMIYCSAGRRGLEIELAADDLVRLLDARIADIAS
>NZ_CP040605.1|WP_168589860.1|1546342_1546975_-|sigma-70-family-RNA-polymerase-sigma-factor
MEPTVNSSEVDRSEETDEQRAARFERDAMPLLDQLYGAALRMTRNAQDAEDLVQETYLRAFSAFKSFAQGTNLKAWLYRILTNTYINGYRKRQRQPQQQPTDEIADWQLAQAENHTSSGLRSAEVEALDRLPDTDVKAALQQLAEEFRMVVYLADVEGFAYKEIAEIMGTPIGTVMSRLHRGRRQLREMLTDVARDRGFLRETKREVSTK
>NZ_CP040605.1|WP_168585233.1|1546013_1546346_-|mycothiol-system-anti-sigma-R-factor
MNCGGPDGASCEDVLAEVWLFLDNECDQQRRAAVQQHLDGCGSCLEHFGIEEHIKALLHRKCGGEHAPTELKDRLRASIREAVLRKAEVTVERGPEGTSVEVRAKRTSAE
>NZ_CP040605.1|WP_168585232.1|1545463_1545679_-|biotin/lipoyl-binding-carrier-protein
MAEEIRAEMVANVMAVSVSEGDSVGDGDSLVLLESMKMEIPVLSEVAGTVSTMAVKPGDVVQEGDLIAVVE
>NZ_CP040605.1|WP_168585231.1|1543939_1545433_-|PAS-domain-containing-protein
MSTLSDLLAEHTGLSGTAADHLQLVVAEWQLLSDLSFADFLLWVPIGPQEAPESRFLCVAQARPTTAPTAHPEDVVGTEVTQEEHPQLRRAALEGRICREEDPRWHLGVPVRRETIPVKLGDEIVAVLSRDTNLAVPRVPSPLEISYLGSAADLCQMVADGTFPTPEPAPDVHTSPRVGDGLIRLDSSGTVVFASPNALSAYHRMGHAADLVGAQLAPLTRSLLNDPFDADEVAQRVRRAMSGQPSMRIEAEARGATVLFRALPLRPRGQQAGALVLVRDVTEVKRRDRALMSKDATIREIHHRVKNNLQTVAALLRLQGRRTVNNEARLALDESVRRVTSIALVHETLSMSVDERVDLDDVVDRVIPMMSDVAAAETGVKVRREGRFGVVSAELATPLVMVLTELVQNAFEHAFPEGQGGEVVVQAERSARWLDVVIFDDGRGLPKGFSLERAERLGLQIVRTLVESELRGSLSLRGRGRQPGTEAVLRVPLKYRR
>NZ_CP040605.1|WP_010304783.1|1543399_1543654_+|WhiB-family-transcriptional-regulator
MDWRHRAVCRDEDPELFFPVGNSGPAVLQIAEAKAVCRRCPVASECLAWALESGQDAGVWGGMSEDERRALKRRNARTRARTNA
>NZ_CP040605.1|WP_168585230.1|1542224_1543151_+|diacylglycerol-kinase-family-lipid-kinase
MRAVLVVNPQATSTTAAGRDVIAHALASELKLDVVETQYWGHASDTARAAVEDGVDLVIAHGGDGTVNEVVNGMFSAADPGDRVMPTLGVVPGGSANVFARALGLPKDPVEATHRLLRAVADGSGRMVGLGKADDRWFTFNAGVGWDAEVVAEVERQRSRGQNVTPALYARTALSCYFRMARRAPLISLQIGHEEPIHQLHSVFISNADPWTYLGSRPVRMSPDTSFDTGLGVFALHNMNAYPVLQHVAEMLRDRGKPHPRNSIQRADVGHLRVTCTEPLRLQVDGDCLGERSAIEFFSVPDALRVAV
>NZ_CP040605.1|WP_168589859.1|1541363_1541795_-|hypothetical-protein
MPTEVVPRTIRIAGVLTTLQGVAGLIFVVALLVRSTAPDLGGVGQFERGQMYGEAGYYTLLAGGVLAAGIGLWKGKHWARTPALLMQLLLLGTAWYAFGPSSQPVIALVIAVPAVAVLWFLFNREGRAWSFSSSTAPDADRDE
>NZ_CP040605.1|WP_168585229.1|1540886_1541354_+|GNAT-family-N-acetyltransferase
MIRRATRADVPAMVELVHELALYEKAPELCHLTEQQLRDALFGPAPALFGHVAEVDGAVAGLSLWFLNFSTWEGVHGIYLEDLYVRPEQRGSGLGKALLQTLAQECVQRGYARLEWSVLNWNEPSINFYKAAGAIPMDEWTAYRLTGDALRNFSA
>NZ_CP040605.1|WP_168585228.1|1540215_1540812_+|acid-phosphatase
MAQDEHRVYVLRHGTTEWSQTGQHTSRSDIPLTVEGELRARQAGQTLSALRPAGPVVVLASPRQRAQRTATLAGLADVGTEPLLAEWDYGDYEGLTAQQIREQVPDWTVWTHPCPGGETAADVTARADKLLTRIADTGSDVVLVGHGHFSRCLIARWLGLSATSGVRFALDPAGITVLGHERGVPQVERSNIPPWQQG
>NZ_CP040605.1|WP_168585235.1|1547930_1548542_-|alpha/beta-hydrolase
MTRVEVETPHGPARAELHCAEEGRAALLLGHGAGAGIAAPDLVAVTRAATEAGVHVALIEQPYRVAGRRAPAPAKQLDTAWLAVVEDLGERWFADLPLIFGGRSSGARVACRTAEAGAASAVLCLAFPVHPPGKPEKSRLGELEGVEAPVLVVQGERDAFGQPEPSHNREVVLVPGDHSLKADVDAVFRAAQEWLGRVLRLLD
>NZ_CP040605.1|WP_168585236.1|1548538_1549255_-|SOS-response-associated-peptidase
MCGRYAVGHDPAELAEEFAAVDRAAGAVGADFNVTPTKTVPIVVQRGAERSIRPVRWGLVPTWAKEIGSGPPMINARAESITTKPAFADSARRRRCLMPATGWYEWRPGDRRRQPYLCTRGSGASLAMAAVFSAWWAPDSTDQPLVTCAVVTTDAVGELADIHHRMPLVLPEHRWADWLDPRRTEIADLLEPEREVLDELAIHPVSTEVNSMRNNHPDLLERVEPLPEPAEQAALFES
>NZ_CP040605.1|WP_168585237.1|1549293_1550058_-|SOS-response-associated-peptidase
MCGRYASTKDPGKLAAEFAALDATGGAAPGADFNVAPTKNVFSVVRRHPRDDAGDRDLERTERTIRVMRWGLVPMWAKEKSIGSRMINAKSETVTTKPAFRSSIKRYRCLLPADGWYEWKREGGRKQPFFMTSPDGSSLAMAGIYASWRDPQAEDAPPLVTCSVLTTSAIGQLTDVHDRMPLLLPATAWEQWLDPDLPDVTDLLGPPPRELVDGLEIRPVSTAVNSVRNNGAKLLERVSLGEQPQAVGLDRDVK
>NZ_CP040605.1|WP_168585238.1|1550265_1551534_+|3-phosphoshikimate-1-carboxyvinyltransferase
MTQLWPAPVARGAVHATVPVPGSKSITNRALVLAALAEGPSTLRAPLRSRDTELMAGALRSLGVEVHDGPDGSWQVTPAEPHGPAEVDCGLAGTVMRFVPPVAALAVGRITFDGDPQARQRPLGTVLDALRELGAEIDGTALPFDVHGTGKLAGGTVTIDASASSQFVSGLLLSAPRFEQGVTVLHQGKPVPSLPHIEMTVSMLRAAGADVDDQEPNTWRVAPGKIHALDVDIEPDLSNATPFLAAAAVTGGTVTVPGWPAQTTQAGDAIREILRQIGAHVQRTEAGLTVTGPDELTPIDIDLHDVGELAPTVAALAALAPGRSQLRGIAHLRGHETDRLAALQNELNKLGGAVEQTEDGLLIEPRPLTGGNWHSYADHRMATAGAILGLRVPGVAVEDIATTAKTIPDFPGMWATMLGETA
>NZ_CP040605.1|WP_168585239.1|1551553_1552564_+|ribosome-small-subunit-dependent-GTPase-A
MRKRGWRDLDESDVRVRPGRRGSRPRSKQRPKHADAAAAMIVAVDRGRWTCALEGDPDQLVTAMRARELGRTPVVVGDRVDLVGDISGKPDTLARIVRVADRTSVLRRTADDTDPYERVVVANAEQLVIVTALADPPPRPGFIDRCLVAAYAGGLTPVLCLTKADLADPGEWIDTYSSLDMPITITRLDAEPEELRALLTDRVSALVGHSGVGKSTLVNRLVPAADRATGEVSGVGKGRHTSTSAVALPLPERGGWVVDTPGIRSFGLAHVTADDVIAAFEGFSEAAEECPPNCGHLGGSDDPECHLDTYASDGGNVEQLASLRRLLRSRAGLDEA
>NZ_CP040605.1|WP_168585240.1|1552722_1553583_+|hypothetical-protein
MPRASRTAVLSAGLALIAALSACGTEPLPQARALMATQPDARPAAGAMLSQVIGKINARGSVRSTVRGSLGMVGELAAEGAVRYRGPLADLAFSGQTRAPGDKPQHIELSIVDGVGYLQTPLTRPAPDKPWLKITPGGADFGAKLLSPALHQLHEAVDPRATFSGVETATRIQQSAPDTVDGKPTTRYDLRVITSQAADVAADPQQRAQFRQAAEDGEPELGYQLWLDESGLPARFAASHEVAQAGKVSLTSTYRDWGAATEIPVPPAGQVGVFEDLPRQAQQPPR
>NZ_CP040605.1|WP_168584345.1|1553739_1555179_+|transposase
MMSVHDTGQADALGELSGFRQRFYECLTGRADALFELTDAVLCSDGPVTSLAELSLAAEHRRGHGAGYDAINHGRVEVDRLRTTLARLPLPRAADGRITLAVDVSPWLRPDAACSPERLFCHVYGRSRSASQLIPGWPYSFVAALETGRTSWTAILDAVRLGPADDATAVTAAQLREVVGRIMDAGHWRPGDPRILIVTDAGYDVTRLAFVLADLPVELVGRIRSDRVLLRPAPPRPPGTVGRPRKHGGVFTLAEENSWHAPDHTTGTDTTRYGHAQARAWDRLHPRLTHRGAWLDHEGELPLVEGTLIRLQVDHLPGDRDPKPVWLWSSVTGASAELVDLLWQAFLRRFDLEHTFRLLKQTLGWTRPKLRAPGSADRWTWLIVVAHTQLRLARPIAEDLRRPWERPVTEARRLTPARVRRGFRNLHAKTGSPAAAPKPSRPGPGRPTGSRNTHRATRHDVGKTIKRDLTLEQHQNRKG
>NZ_CP040605.1|WP_168585241.1|1555381_1555555_+|hypothetical-protein
MWLDAEGLPIKANSTTPALNVAGQQIPESTMTVHYSDWGKPVQINVPPADQAQEKQQ
>NZ_CP040605.1|WP_168585242.1|1555647_1556151_-|hypothetical-protein
MRVYLPATVPMLRRLVEEKQLQPLGGTAFALTPALRESYASGDTEELEYAAMREAARASLRLIAGDLGAGEKVELRRVVISVDVEDVNLRPDLDHAVVKVAGPVQWRQLAAVHVDATEAEEAVRAAAEVIDAADLGDPDAEFTLGEAEDHELAWYAPQEVPFLLELM
>NZ_CP040605.1|WP_168585243.1|1556147_1557581_-|wax-ester/triacylglycerol-synthase-family-O-acyltransferase
MSDRLSAVDASFLYLEDYTTPMHVGGVAVFRRPRTGFDYDKVLALIDRRLGLVPRYRQRVMQVPGGLVRPVWVDDQDFDITYHVRRSALPKPGNDDQLHDLAARLMSRKLDHTRPLWEIYLVEGLSKNRVAVITKTHQAMVDGIGAIDIGQVILDVECDREVPDADELWMPRPEPSLAELLVEAMTDAVQRPGEVVENVRAAVADATATVQKVTRALGGVASALRTAVVPAPSGPLNAPTSTQRRFAVARAKLDDLRAVRRAHGSTVNDVVLAVVTGALRNWLLSRGEVVTPSMTVRAMVPVSVRSDDEARATYPETGSLPVGSVGGKVSAYLVDLPVGEGNTIVRLHQVSHAMRAHAESGQSVAASALVKVSGFAPPTLHALGARVANQFSDRLFNVLVTNVPGPQVPLYAAGARMMEMFPVVPLAKNQSLSVGVTSYDGGVYFGLNADRDAMPDVDVLAAMIGEAVDEMIGTVDA

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Crispr_ID: NZ_CP040605_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_9

1625815-1625917

Orphan

Consensus_repeat	Method
CTGCATGGCGGCCGATTGTTGCGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040605_9

>merge|NZ_CP040605|9|1625815-1625917|CRISPRCasFinder
CTGCATGGCGGCCGATTGTTGCGCATAAGCCTGATAGTGCTGCGCAGCAGCGATTTGCTGTTCGGGTCCAACCGGATACTGCATGGCGGCCGATTGTTGCGCA

>NZ_CP040605|9|8|1625815-1625917|CRISPRCasFinder
CTGCATGGCGGCCGATTGTTGCGCA	TAAGCCTGATAGTGCTGCGCAGCAGCGATTTGCTGTTCGGGTCCAACCGGATA
CTGCATGGCGGCCGATTGTTGCGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168585273.1\|1614846_1616031_-\|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl\|CDD\|235674
NZ_CP040605.1\|WP_168585279.1\|1623587_1623887_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168585277.1\|1621866_1622541_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP040605.1\|WP_168589873.1\|1624188_1625736_-\|DUF2339-domain-containing-protein	unknown	unknown	gnl\|CDD\|378390
NZ_CP040605.1\|WP_168585274.1\|1616205_1616979_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168585284.1\|1629604_1630069_-\|YbaB/EbfC-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|376829
NZ_CP040605.1\|WP_168585286.1\|1631436_1632402_-\|hydroxymethylglutaryl-CoA-lyase	unknown	unknown	gnl\|CDD\|163676
NZ_CP040605.1\|WP_168585278.1\|1622655_1623429_+\|histidinol-phosphatase	unknown	unknown	gnl\|CDD\|238819
NZ_CP040605.1\|WP_168585289.1\|1634634_1635270_+\|septum-formation-inhibitor-Maf	unknown	unknown	gnl\|CDD\|178901
NZ_CP040605.1\|WP_168585287.1\|1632401_1632923_-\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|367615
NZ_CP040605.1\|WP_168585288.1\|1632997_1633828_-\|biotin--[acetyl-CoA-carboxylase]-ligase	unknown	unknown	gnl\|CDD\|223417
NZ_CP040605.1\|WP_168585280.1\|1623879_1624065_+\|DUF397-domain-containing-protein	unknown	unknown	gnl\|CDD\|377231
NZ_CP040605.1\|WP_168585281.1\|1626503_1626809_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168585276.1\|1620585_1621860_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP040605.1\|WP_168585290.1\|1635883_1636228_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168585283.1\|1629281_1629611_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168585275.1\|1619749_1620277_+\|GtrA-family-protein	unknown	unknown	gnl\|CDD\|377229
NZ_CP040605.1\|WP_168585285.1\|1630786_1631440_-\|adenosylcobinamide-amidohydrolase	unknown	unknown	gnl\|CDD\|376682
NZ_CP040605.1\|WP_168585282.1\|1626805_1629274_-\|glycohydrolase-toxin-TNT-related-protein	unknown	unknown	gnl\|CDD\|379424
NZ_CP040605.1\|WP_168589872.1\|1614290_1614779_-\|5-(carboxyamino)imidazole-ribonucleotide-mutase	unknown	unknown	gnl\|CDD\|376377

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168585273.1\|1614846_1616031_-\|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl\|CDD\|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	5.97568e-172
NZ_CP040605.1\|WP_168585277.1\|1621866_1622541_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.6601e-76
NZ_CP040605.1\|WP_168589873.1\|1624188_1625736_-\|DUF2339-domain-containing-protein	gnl\|CDD\|378390	pfam10101, DUF2339, Predicted membrane protein (DUF2339). This domain, found in various hypothetical bacterial proteins, has no known function.	2.25294e-10
NZ_CP040605.1\|WP_168585284.1\|1629604_1630069_-\|YbaB/EbfC-family-DNA-binding-protein	gnl\|CDD\|376829	pfam02575, YbaB_DNA_bd, YbaB/EbfC DNA-binding family. This is a family of DNA-binding proteins. Members of this family form homodimers which bind DNA via a tweezer-like structure. The conformation of the DNA is changed when bound to these proteins. In bacteria, these proteins may play a role in DNA replication-recovery following DNA damage.	0.000906427
NZ_CP040605.1\|WP_168585286.1\|1631436_1632402_-\|hydroxymethylglutaryl-CoA-lyase	gnl\|CDD\|163676	cd07938, DRE_TIM_HMGL, 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain. 3-hydroxy-3-methylglutaryl-CoA lyase (HMGL) catalyzes the cleavage of HMG-CoA to acetyl-CoA and acetoacetate, one of the terminal steps in ketone body generation and leucine degradation, and is a key enzyme in the pathway that supplies metabolic fuel to extrahepatic tissues. Mutations in HMGL cause a human autosomal recessive disorder called primary metabolic aciduria that affects ketogenesis and leucine catabolism and can be fatal due to an inability to tolerate hypoglycemia. HMGL has a TIM barrel domain with a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. The cleavage of HMG-CoA requires the presence of a divalent cation like Mg2+ or Mn2+, and the reaction is thought to involve general acid/base catalysis. This family belongs to the DRE-TIM metallolyase superfamily. DRE-TIM metallolyases include 2-isopropylmalate synthase (IPMS), alpha-isopropylmalate synthase (LeuA), 3-hydroxy-3-methylglutaryl-CoA lyase, homocitrate synthase, citramalate synthase, 4-hydroxy-2-oxovalerate aldolase, re-citrate synthase, transcarboxylase 5S, pyruvate carboxylase, AksA, and FrbC. These members all share a conserved triose-phosphate isomerase (TIM) barrel domain consisting of a core beta(8)-alpha(8) motif with the eight parallel beta strands forming an enclosed barrel surrounded by eight alpha helices. The domain has a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. In addition, the catalytic site includes three invariant residues - an aspartate (D), an arginine (R), and a glutamate (E) - which is the basis for the domain name "DRE-TIM".	3.75607e-156
NZ_CP040605.1\|WP_168585278.1\|1622655_1623429_+\|histidinol-phosphatase	gnl\|CDD\|238819	cd01641, Bacterial_IMPase_like_1, Predominantly bacterial family of Mg++ dependend phosphatases, related to inositol monophosphatases. These enzymes may dephosphorylate fructose-1,6-bisphosphate, inositol monophospate, 3'-phosphoadenosine-5'-phosphate, or similar substrates.	2.42881e-90
NZ_CP040605.1\|WP_168585289.1\|1634634_1635270_+\|septum-formation-inhibitor-Maf	gnl\|CDD\|178901	PRK00148, PRK00148, Maf-like protein; Reviewed.	5.83251e-98
NZ_CP040605.1\|WP_168585287.1\|1632401_1632923_-\|PH-domain-containing-protein	gnl\|CDD\|367615	pfam03703, bPH_2, Bacterial PH domain. Domain found in uncharacterized family of membrane proteins. 1-3 copies found in each protein, with each copy flanked by transmembrane helices. Members of this family have a PH domain like structure.	3.07363e-18
NZ_CP040605.1\|WP_168585288.1\|1632997_1633828_-\|biotin--[acetyl-CoA-carboxylase]-ligase	gnl\|CDD\|223417	COG0340, BirA, Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism].	2.08535e-66
NZ_CP040605.1\|WP_168585280.1\|1623879_1624065_+\|DUF397-domain-containing-protein	gnl\|CDD\|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.17513e-17
NZ_CP040605.1\|WP_168589872.1\|1614290_1614779_-\|5-(carboxyamino)imidazole-ribonucleotide-mutase	gnl\|CDD\|376377	pfam00731, AIRC, AIR carboxylase. Members of this family catalyze the decarboxylation of 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR). This family catalyze the sixth step of de novo purine biosynthesis. Some members of this family contain two copies of this domain.	9.05318e-81
NZ_CP040605.1\|WP_168585275.1\|1619749_1620277_+\|GtrA-family-protein	gnl\|CDD\|377229	pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of undecaprenyl phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane. Another member of this family is a DTDP-glucose-4-keto-6-deoxy-D-glucose reductase, which catalyzes the conversion of dTDP-4-keto-6-deoxy-D-glucose to dTDP-D-fucose, which is involved in the biosynthesis of the serotype-specific polysaccharide antigen of Actinobacillus actinomycetemcomitans Y4 (serotype b). This family also includes the teichoic acid glycosylation protein, GtcA, which is a serotype-specific protein in some Listeria innocua and monocytogenes strains. Its exact function is not known, but it is essential for decoration of cell wall teichoic acids with glucose and galactose.	4.67446e-22
NZ_CP040605.1\|WP_168585285.1\|1630786_1631440_-\|adenosylcobinamide-amidohydrolase	gnl\|CDD\|376682	pfam01955, CbiZ, Adenosylcobinamide amidohydrolase. This prokaryotic protein family includes CbiZ which converts adenosylcobinamide (AdoCbi) to adenosylcobyric acid (AdoCby), an intermediate of the de novo coenzyme B12 biosynthetic route.	6.39056e-52
NZ_CP040605.1\|WP_168585282.1\|1626805_1629274_-\|glycohydrolase-toxin-TNT-related-protein	gnl\|CDD\|379424	pfam14021, TNT, Tuberculosis necrotizing toxin. This is the C-terminal domain secreted by Mycobacterium tuberculosis (Mtb). It induces necrosis of infected cells to evade immune responses. Mtb utilizes the protein CpnT to kill human macrophages by secreting its C-terminal domain (CTD), named tuberculosis necrotizing toxin (TNT) that induces necrosis. It acts as a NAD+ glycohydrolase which hydrolyzes the essential cellular coenzyme NAD+ in the cytosol of infected macrophages resulting in necrotic cell death. CpnT transports its toxic CTD from the cell surface of M. tuberculosis by proteolytic cleavage, where the toxin is cleaved to induce host cell death. Structural analysis determined that the TNT core contains only six beta-strands as opposed to seven found in all known NAD+-utilizing toxins, and is significantly smaller, with only two short alpha-helices and two 3/10 helices. Furthermore, the putative NAD+ binding pocket identified Q822, Y765 and R757 as residues possibly involved in NAD+-binding and hydrolysis based on similar positions of catalytic amino acids of ADP-ribosylating toxins. While glutamine 822 residue was detected to be highly conserved among TNT homologs.	3.07677e-30
NZ_CP040605.1\|WP_168585276.1\|1620585_1621860_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.50203e-35

>NZ_CP040605.1|WP_168589873.1|1624188_1625736_-|DUF2339-domain-containing-protein
MEPSRVLAWVGAGVTLLGVVFLLVLAVQQEWLGPGARVAGGAVLAALLVAAGWWMHCRSAADESGGAGRIAGFALATTGFGALFLDVVAATALYDYLPVPTGLGVGLAVSVAGLALADRWRAQPLALGVVLSSAICAPLITQTADSLLVGFVVLVQVAATPVQVRRGWAGLAVAAGVPTVLAALAASVRGIWIHDTALVVAIFAAAVLGVAVAAITAGARPDADGTAIGLLIAAPTPAFLTGPLMLERPAAGAIGTAMVVLLVGIWAAGRFTPAFRNRLSTRFVAAAGGMAAVAAVQTTLTFLDSSSWGTALLCEALLLGVGGFLLRSPGVLLGATCYATFGFLLAFFNELPITALLWHDGGTGIRGLLAGLLVALVAVALPVAATRIGKLAELPGSLPLWAASGLALLYATASATMAACLLVSDARESFLTGHILITLSWVVAAIALLLRGVRVKHLRIAGLVLIAVSLAKLLLFDLATLDGFARVIAFLCAGLILLAAGSAYARLLNRGKPTE
>NZ_CP040605.1|WP_168585280.1|1623879_1624065_+|DUF397-domain-containing-protein
MSELVWRKSSRSGSVHNCVEVAMTPDATAVRDSKDPDGGTLAFNIGRWHSFLSAIKADHYR
>NZ_CP040605.1|WP_168585279.1|1623587_1623887_+|hypothetical-protein
MREQLEHLLILQRRDNVSLRMVPLTATPHPALDGSFSLYELRDGTSHVFVEARYFAVALTEPADVEPFMKACQKLDHCALDKEESTCLIKDIVGRLGDE
>NZ_CP040605.1|WP_168585278.1|1622655_1623429_+|histidinol-phosphatase
MTRDLDLALHLADVADGITVGRFRARDLSVDRKPDRTPVTDADLAVEDAVREVLGAQRPDDVVAGEERGGAAGAGRAWVLDPIDGTKNFLRGIPVWATLIALVDDGRPVVGVISAPALGKRWWAAAGAGAWCRTGDAEPERIGVSGVRDLADAYVSTTHLGTWVEYHSRESYLRLIDACWENRAFGDFWHHCLVAEGVIDIAAEPIVNPWDVAAAQVLVEEAGGTFTDLSGNPRYDGGSALSTNGHLHSEALQLLQK
>NZ_CP040605.1|WP_168585277.1|1621866_1622541_-|response-regulator-transcription-factor
MSVVLLAEDDPAIAVPLSRALQREGYSVQVSEDGPSTLRAAASGGIDLLVLDLGLPEMDGLEVCRRLRAQGRGLPVLMLTARTDEVDFVVGLDAGADDYVAKPFRLAELMARIRALLRRGAPETLEASGVRLDLTARRVLVNEHEVQLANKEYELLRVLMQHAGQVVTREEILEEVWPESDRKGSKTLDMHISWLRRKLSDSNGRLDETRIATVRGVGFRFNAD
>NZ_CP040605.1|WP_168585276.1|1620585_1621860_-|HAMP-domain-containing-histidine-kinase
MRRRILQATLLAVAVTAVVLGLPLGFSALKLVQDLTAGDLTTRAQQIATLLDEQIASQRSIDLNAARLAVPDGARLIVRTQAHDYVYGPDPGQDPLVESVPMVQSGTVTIAAPSAPVRTQQLQVAALVLMLVVLSAGTGMIVATLTARRLADPLKHVAARAARLGAGDFRADPQRHQVPELDRVADALDASGAALSQLVQRERDLVGDVSHQLRSRLTALHLRLEALAAADDPEIAEEASAALEQAERLSGVLDDLLAAATAARARDAEPLDVSSLLTDVAGEWREPLKAAGRTLRLKVSEGLLARATPTRLRETIGVLLDNALRHGEGTVMLAARQGGGTVVVEVGDSGPGVPDALVPYLFERGFSGRGSTGVGLALARALVEADGGRLELSQARPAMFEVFLPIARADDILGVSWNRESTPR
>NZ_CP040605.1|WP_168585275.1|1619749_1620277_+|GtrA-family-protein
MSAVDSVLARIPQPYRSLAIRHRELLKFGVVGAITFFIDTGIFYALKLTILSPKPVTSKVIAVLVATIVSYVLNREWSFRTRGGRRRHYEATLYFVISGIGVGLYSAPLWISRYMLHLQTPFTSRLVEEIADFTSGQIIGLLVGMAFRWWAFRKWVFPAEQPDRRPSPRDRISAR
>NZ_CP040605.1|WP_168585274.1|1616205_1616979_-|hypothetical-protein
MTDEGRRRALRSRWRTASLAAGWPFPSDWASDAVDAVCSAVVAEEDLADPLADLGASRAEAGVGLAGTLQDLAALHAVSEGEHDGLVSADPDAVPAAMVRATALGWSDVVARMSVGREVEDPLTGLTTAGYLRTRLHEVYRAARVEGRAAGDGHALVTVSLAVNADDYPQMMAMVLIADALRIVFDGGETTSLLRSATAVVLASRDRLLPARCLQARWTIQHRLAADPALHGCGPLLLREELLPDDHDQACELLASL
>NZ_CP040605.1|WP_168585273.1|1614846_1616031_-|5-(carboxyamino)imidazole-ribonucleotide-synthase
MDHRTGTPVVGMIGGGQLARMTHQAAIPLGQSLKVLATSADDAAALVVPNVEIGHHADLDALKNFAQGCDVVTFDHEHVPGEHLRVLAAAGVSVQPGPDALLHAQDKLVMRRKLAELGLPVPPFAEVTEVADVLEFGAEHGWPCVLKTARGGYDGRGVWVLDTPDGAKHTVTELLGSGAQLLVEQRVPLRRELAALVARSPFGQGAAWPLVETVQEDGICVQVLAPAPNASAELVEQAQGLALKIAESLDVTGVLAVELFETDDGLVINELAMRPHNSGHWTIEGSRTSQFEQHLRAVLDYPLGSTEQTAPAVVMANLLGSPIELKMGVDERLHHLFARYPHAKVHLYGKSERPGRKLGHVTVLGDRMDEVREQARLAAHWLSHAEWLDGHQIH
>NZ_CP040605.1|WP_168589872.1|1614290_1614779_-|5-(carboxyamino)imidazole-ribonucleotide-mutase
MGSDSDWPVMQAAADALTEFDVPFEAGVYSAHRTPQRMLDYARTAADRGIRVIIAGAGGAAHLPGMVASATVLPVIGVPVPLKYLDGMDSLLSIVQMPAGVPVATVSVGGARNAGLLAVRTLAADSGELGARLRADMSKFQSDLEEMVLGKHAALQEKATQR
>NZ_CP040605.1|WP_168585281.1|1626503_1626809_-|hypothetical-protein
MNTESVLGWLVAMGVPEDLVSVGAEADDAWCLVRDEVDGAPAWEVFWREQGNRYDWARFTSEQVACFYLFGRLTWTQALRGAVGPVDVTSTPAKGTVAHRA
>NZ_CP040605.1|WP_168585282.1|1626805_1629274_-|glycohydrolase-toxin-TNT-related-protein
MGIELPAELKDVAARTGAKWPEADEDKMRESASAWRDAAKSIEALTSAADSTAQGALGAFDGEAAQAARRDWDKLVADDGVLPSSAKQCRAAADRLDHAAEQVGAAKVQLVRELVVLAKQTDAAEQAAAAGHPQALAALDSALNGAAANVAQVHNTLTSAVDLDSGVLVEPHGPQGLLSADGDALGAASSTVDAAVTHGADAVSGAAGAVGETAHGAVDGVGRVASETADGVGRVASETVGGAAEGIGRAAHETVGGAAGGVGRAAHDTVGDVGGAVEGVGRSAHGTVGGVAAGAHGAVEEVARTAGPWQGDAEHTGPVKVDPGGWAPGLADAHTGPIPVIGDSARSGWTPEGGDPASSTAPHAVHSAWASPQAPQPPLAGAAAPSQGFGPPPPAAQGGHFVAQPGAPGAPPVSAAPPPAAAARPPMPPVAPRGPIAFGSPGSQAPQAPQPQTHKPQAPQPQTHQPQTHQPMQRAPLRPLPAPAQPPAPVVPDAPQRPLRQGSRNADVVAFVLHQFPIGYMPVAASRASRQLPVPEAVEEDRPGLSFPPQDHPQSHLVDDSDALERARSAEVYAAAQRDRAERSEPEQLPAELTEGHEPLGELSEPEWERRFLARVGERSEYAWPPAAEFPEGGVEPAEPVVLEPDTVLDCLGSGDGRILFAAATPFAQRSLPAAYDERDYRRYRVMRPLPVWQAVAAPWFAQPGGGKRYRATYSLIDLVGLGYLVELTKAREVAEAATLRIAREDVSDGGAVVSTVDSPREEATSEDDGKTAVASTERITRDDVEVKAAEAGVASKLRIARDEADDGPATTDGATAQEAAK
>NZ_CP040605.1|WP_168585283.1|1629281_1629611_-|hypothetical-protein
MVTMSGFRSDLGQLTKHAGEFGGLAGQARRIADTLREALDVAGDCWGGDEIGASFARTHCGRAGQALDDLGAMSGRLHDMGEKFAATVATTGQADAGNADVLGRLAGRG
>NZ_CP040605.1|WP_168585284.1|1629604_1630069_-|YbaB/EbfC-family-DNA-binding-protein
MSTDHRAQVAELMADYRRSRERLAETHHDLSSIAETARSEDGSVQVVVGPQGVLREVVLSGDVYERQRPAQLAATIVQLTAAAAQAASRRAADVLAEVLPAGTDPELLLGGRADGASDSAPRNESRRIDDNVDDDDDDFSDASWLRQGPAERKW
>NZ_CP040605.1|WP_168585285.1|1630786_1631440_-|adenosylcobinamide-amidohydrolase
MSAPTAALHTLHGRPLLAWRCARQWLAISSATHGGGIGPRSWVLNATVVTDYDHPDPAAHVAEMADELGLSGGGVGLLTAVDVRHEVTSVDGGVQASVTTGVSHPIWAAAREPAAQAWTPGTINAVCWSPVRLSEAALVNAVATVTEAKAQALVESGVAGTGTVTDATVVLCPLDGEAEPYGGPRSRVGAGLARTVHAAVTAGLRVQHPRRREDPDR
>NZ_CP040605.1|WP_168585286.1|1631436_1632402_-|hydroxymethylglutaryl-CoA-lyase
MGPRELGLPMQMASPEPGELPTEVTIWEVGARDGLQNEKEVVPVEVKLEFLQRMADAGLGVLEATSFVRPEWVPQLADAAELLAGLQRAPGVRYPVLVPNARGLDRALESGVRDIAIFAAATETFTQRNLNRSLDEQFAMFDPVVQRAVGEGLAVRGYVSMCFGDPWEGAVPVEQVVSVGKRLLEMGCWQLSLGDTIGVATPGHVEALVRAFVAAGVRVDRLAVHFHDTYGQALANTYAALRLGVSTVDSSAGGLGGCPYAKSATGNLATEDLVWMLDGLGLKHGVDLGKLVETSVWMAERLGRPSPSRVVKALGTAASGS
>NZ_CP040605.1|WP_168585287.1|1632401_1632923_-|PH-domain-containing-protein
MTYPDGLLGADEHVVVHKHPHWKMLIVPVLVLFLVVGGGSYLAALAAPTSWHLPAWIGLGVVGAVLIIWFTLAPLVRWRTTHFVVTTHRLMVREGVFTRTGIDIPMSRINSVRFRHGLLDRILGCGTLVVESASDEPLEFDDIPQVERVHTLLYREVNDDPRDDWGYRTREDD
>NZ_CP040605.1|WP_168585288.1|1632997_1633828_-|biotin--[acetyl-CoA-carboxylase]-ligase
MGVPVLLDGERLRARLVDGGPFAALDVVTTTGSTNTDLVAAAGRGAADRTVLIAEEQHAGRGRMQRQWASHRGHGLFLSVLLRPKVPQAAIAWLPLIAGVALAETVDRATGVPATLKWPNDLLLGDGGEWSKGAGILAEAVAGPDGMAIVLGMGINVFQQREDLPRGAGGLPATSLAAEGAEVDREEFAVALLTSFAEVDDRWRGAAGDVVASGLLDRYRRLCSTLGQQVRVELGADDQLRGVATDIDETGRLVVRSADGGTTAVSAGDVVHLRRA
>NZ_CP040605.1|WP_168585289.1|1634634_1635270_+|septum-formation-inhibitor-Maf
MRFVLASASSARLSVLRSAGIEPLVQVSGVDEDAVAAALPDPSPAELVSALAQAKAEAVVADIAAAEPNAVIVGCDSMLLMAHGEIVGKPGTREAAAKRWAQNAGSSGELLTGHAIVRLQDGEISARAQGHLSTTVRFGEPTEAELDAYLETGEPLHVAGGFTLEGFGGWFIEGVDGDPSSVLGISLPLTRKLLAEVGVSVVTLWSSPNTE
>NZ_CP040605.1|WP_168585290.1|1635883_1636228_-|hypothetical-protein
MIAALVASGLLGVGGLALWATFYYAPAQHAGSGEGALTVAYLVARVEAETRGHGRHQLREPRTVQMRGDLADALAVEETRHLPLIESGLPVDDREAMARHPGMLRRLLAALQSL

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Crispr_ID: NZ_CP040605_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_10

1889833-1889907

Orphan

Consensus_repeat	Method
CTGCTGGGGCGGGTACTGCTACTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040605_10

>merge|NZ_CP040605|10|1889833-1889907|CRISPRCasFinder
CTGCTGCCGCGGAAACTGCTGGGGCGGGTACTGCTACTGCGGCGGGTACTGCTGCTGCGGCGGGTACTGCTGCTG

>NZ_CP040605|10|9|1889833-1889907|CRISPRCasFinder
CTGCTGCCGCGGAAACTGCTGGGG	CGGGTACTGCTACTGCGGCGGGTACTG
CTGCTGCGGCGGGTACTGCTGCTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168585467.1\|1881254_1882538_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238045
NZ_CP040605.1\|WP_168585475.1\|1890686_1890845_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168589912.1\|1892482_1892986_-\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888
NZ_CP040605.1\|WP_168585471.1\|1889341_1889647_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168585465.1\|1879519_1880008_-\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|239217
NZ_CP040605.1\|WP_168585468.1\|1883184_1885047_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP040605.1\|WP_168585473.1\|1890121_1890319_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168585476.1\|1893827_1894118_-\|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl\|CDD\|274862
NZ_CP040605.1\|WP_168585479.1\|1895048_1896878_-\|type-VII-secretion-associated-protein	unknown	unknown	gnl\|CDD\|212667
NZ_CP040605.1\|WP_168585474.1\|1890533_1890677_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168585463.1\|1876198_1877344_-\|alanine-racemase	unknown	unknown	gnl\|CDD\|143481
NZ_CP040605.1\|WP_168585470.1\|1886618_1889342_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236090
NZ_CP040605.1\|WP_168585478.1\|1894630_1894984_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_010316190.1\|1893012_1893459_-\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
NZ_CP040605.1\|WP_168584085.1\|1886187_1886622_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367150
NZ_CP040605.1\|WP_168585464.1\|1877664_1879182_-\|NAD(P)H-hydrate-dehydratase	unknown	unknown	gnl\|CDD\|238576
NZ_CP040605.1\|WP_168585477.1\|1894180_1894492_-\|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl\|CDD\|274862
NZ_CP040605.1\|WP_168589911.1\|1890896_1892231_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237672
NZ_CP040605.1\|WP_168585466.1\|1880004_1880982_-\|hydroxymethylbilane-synthase	unknown	unknown	gnl\|CDD\|234612
NZ_CP040605.1\|WP_168585469.1\|1885163_1886000_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|177659

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168585467.1\|1881254_1882538_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.12851e-06
NZ_CP040605.1\|WP_168585479.1\|1895048_1896878_-\|type-VII-secretion-associated-protein	gnl\|CDD\|212667	cd10170, HSP70_NBD, Nucleotide-binding domain of the HSP70 family. HSP70 (70-kDa heat shock protein) family chaperones assist in protein folding and assembly and can direct incompetent "client" proteins towards degradation. Typically, HSP70s have a nucleotide-binding domain (NBD) and a substrate-binding domain (SBD). The nucleotide sits in a deep cleft formed between the two lobes of the NBD. The two subdomains of each lobe change conformation between ATP-bound, ADP-bound, and nucleotide-free states. ATP binding opens up the substrate-binding site; substrate-binding increases the rate of ATP hydrolysis. HSP70 chaperone activity is regulated by various co-chaperones: J-domain proteins and nucleotide exchange factors (NEFs). Some HSP70 family members are not chaperones but instead, function as NEFs to remove ADP from their HSP70 chaperone partners during the ATP hydrolysis cycle, some may function as both chaperones and NEFs.	2.64816e-86
NZ_CP040605.1\|WP_168589912.1\|1892482_1892986_-\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	3.46392e-76
NZ_CP040605.1\|WP_168589911.1\|1890896_1892231_-\|phosphoglucosamine-mutase	gnl\|CDD\|237672	PRK14318, glmM, phosphoglucosamine mutase; Provisional.	0
NZ_CP040605.1\|WP_168585468.1\|1883184_1885047_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP040605.1\|WP_168585476.1\|1893827_1894118_-\|WXG100-family-type-VII-secretion-target	gnl\|CDD\|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	1.81131e-11
NZ_CP040605.1\|WP_168585463.1\|1876198_1877344_-\|alanine-racemase	gnl\|CDD\|143481	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase. This family includes predominantly bacterial alanine racemases (AR), some serine racemases (SerRac), and putative bifunctional enzymes containing N-terminal UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase (murF) and C-terminal AR domains. These proteins are fold type III PLP-dependent enzymes that play essential roles in peptidoglycan biosynthesis. AR catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. SerRac converts L-serine into its D-enantiomer (D-serine) for peptidoglycan synthesis. murF catalyzes the addition of D-Ala-D-Ala to UDPMurNAc-tripeptide, the final step in the synthesis of the cytoplasmic precursor of bacterial cell wall peptidoglycan. Members of this family contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. AR and other members of this family require dimer formation and the presence of the PLP cofactor for catalytic activity. Fungal ARs and eukaryotic serine racemases, which are fold types I and II PLP-dependent enzymes respectively, are excluded from this family.	1.10486e-152
NZ_CP040605.1\|WP_168585470.1\|1886618_1889342_-\|hypothetical-protein	gnl\|CDD\|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	3.44369e-06
NZ_CP040605.1\|WP_010316190.1\|1893012_1893459_-\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	8.28499e-103
NZ_CP040605.1\|WP_168584085.1\|1886187_1886622_-\|hypothetical-protein	gnl\|CDD\|367150	pfam02711, Pap_E4, E4 protein. This is is a family of Papillomavirus proteins, E4, coded for by ORF4. A splice variant, E1--E4, exists but neither the function of E4 or E1--E4 is known.	3.26787e-06
NZ_CP040605.1\|WP_168585464.1\|1877664_1879182_-\|NAD(P)H-hydrate-dehydratase	gnl\|CDD\|238576	cd01171, YXKO-related, B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily.	1.73468e-62
NZ_CP040605.1\|WP_168585477.1\|1894180_1894492_-\|WXG100-family-type-VII-secretion-target	gnl\|CDD\|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	3.45442e-08
NZ_CP040605.1\|WP_168585466.1\|1880004_1880982_-\|hydroxymethylbilane-synthase	gnl\|CDD\|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	1.14685e-105
NZ_CP040605.1\|WP_168585469.1\|1885163_1886000_+\|alpha/beta-hydrolase	gnl\|CDD\|177659	PLN00021, PLN00021, chlorophyllase.	5.08773e-06
NZ_CP040605.1\|WP_168585465.1\|1879519_1880008_-\|NUDIX-hydrolase	gnl\|CDD\|239217	cd02883, Nudix_Hydrolase, Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ for their activity. Members of this family are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site. Substrates of nudix hydrolase include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and "house-cleaning" enzymes. Substrate specificity is used to define child families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required. This superfamily consists of at least nine families: IPP (isopentenyl diphosphate) isomerase, ADP ribose pyrophosphatase, mutT pyrophosphohydrolase, coenzyme-A pyrophosphatase, MTH1-7,8-dihydro-8-oxoguanine-triphosphatase, diadenosine tetraphosphate hydrolase, NADH pyrophosphatase, GDP-mannose hydrolase and the c-terminal portion of the mutY adenine glycosylase.	1.47768e-17

>NZ_CP040605.1|WP_168585471.1|1889341_1889647_-|hypothetical-protein
MSGAQTSGSDVGKAANAFSDGSGAIKEQAKAATDTKLTAEKFGKKFHEAGKAYKDALDKLGKNIESFAEHGSKLSESFSESAKEYQARDESGAQEVGKVQA
>NZ_CP040605.1|WP_168585470.1|1886618_1889342_-|hypothetical-protein
MADENKQEEESSFGEDVGSVVGGIQGGVTGLVLGPAGAAAGAKIGSEIGGAIGGAAQDAGEWLGETASDAGTWLVDNAGSIADTAMSVVNPIGGKLFESLTDGGFSALQEKAKAAEERKGKFEDAKGKLEGGGAVNTSDELLDEGKMGLDFFEKFLPLYQDWAGKGPDFKGEVVQEYDQLREIDFGAFRADAERLGGVQKALLDQNDSMGQAFRGAKQTWKGSAADAAESKVGSYSMAGTTVTNETENMAGAITPAADGIQQTVREYAKFVLELGKEIKCAGKDPDDTKDEIRKARGDINLEDLKDIGIDDIFSGAWSIIKDQAIGLILGGPIGGLIGQFFGAKDACDQIRQGLIDDAKKWLDESFKPEMEQKYQSFKDQSKATQDAVQAAYDQMLQAAKVSDDPFKGLEDGKGGGGDDQGGGNNTGGGGNNTGGGGSGTGGGGSGTGGGGSGTGGGGGEPEMPKTPEMPKTPEMPEMPEAPGAGGGLGEQGEQEKVTLGEGDDAVTVQKPGPDGKTQVELIGPDGKPKTYEVDFGPAGGAGAPGTEGIQTMPAPGQASGGVGGPPGGQGPIPVQAGEDGKAVIREGDRTITLERTPDGQVKVSVDNGGGQPPLNQTIDFGSDQAKPIDGADRITTMPAEAQPGEVPRPSDATTMPAPAPGFAVPDVGTMPAPDPVAPMPAPDPGFAAPDVGTMPAPDPGFAAPDYGSGVGTMPAADPGFGSPAYGVGSTMPSYDTSGEVPAGSEPAAAGTPASTAPQSAGMSVFSSMSDGVQNSFGSASGQLFGGPDQPGVPGGSDQHGSTGLASLGDSAGGSPQGATGLSSLGGDQSSGSAQGAHAGQSANQSSAMGGAMMGGMGAMGGGHGGQQGGEQERSNSSPWRTQGQLFDDGVDSSNMRFRSVLGEDRER
>NZ_CP040605.1|WP_168584085.1|1886187_1886622_-|hypothetical-protein
MSAVVLINQKVADEIATLVARHRYGVEDSMDAVRAAEAASAKKNEEIKAAADERKQELVEKAANAQPPEDKPRNDWAGKRNEDSNEISLGADDEEERPQQPARPTPPPPPPPPPPPPPAAPKPAPRRRVAFDDDDDYENQSWLR
>NZ_CP040605.1|WP_168585469.1|1885163_1886000_+|alpha/beta-hydrolase
MARTAKKAPSAKNAFEELSRRGPHDVLHGDLALVGLPGIVCTPRSGLGLPAVAFGHGWLQPPRRYLGLLRHLASWGIVVAAPGTQRGVFASHRLYAADLRTALDVCVGVRLGEGGISVDEKRLGVAGHAMGGGCAVLAAAEDQRIRSVATLAAAETMPSAFETASRVEVPGLHIAAGRDLLTPPVANAEPIARAWGGPVQLRTVKKASHLGFTEGRHWTQLVLHGKPEYATQRVTKALLTAFFLCTLGGDRRGEALLSADIGGSHIDNEHSRGDLTAA
>NZ_CP040605.1|WP_168585468.1|1883184_1885047_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYVGHRQALEVVLGGLRRLEYRGYDSAGVALLDGEGGLAVERAAGALSNLEKRLAEVDGGKFAGHSGMGHTRWATHGAPTDRNAHPHRDASGQVAVVHNGIIENFAVLRAELEAAGIEMASDTDTETTAHLVAAAYVDGPTAGDLTASVCAVARRLEGAFTLVVTHAAEPGKIVAARRSSPLVVGVGEGEHFLASDVAAFIEHTRDAVELGQDQVVTITRDGYRVTDFFAEDVEAKPFSVDWDLSAAEKGGHDYFMLKEIEEQPEALENTLRGHFAGGGIILDELRLTEQDLRDIDKVFVVACGTAYHSGLLAKYAIEHWCRVPVEVELASEFRYRDPVLGRDTLVVAISQSGETADTLEAVRHARTQRARVLAICNTNGAQIPRESDAVLYTHAGPEIGVAATKTFLAQVAANYLVGLALAQARGTKYSDEVAREFAELSAMPEAVRSTLSTVDQVRQLGQELADAKAVLFLGRHVGYPVALEGALKLKELAYMHAEGFAAGELKHGPIALIEEGLPVVVVMPSPKGRALLHSKLVSNIREIQARGARTIVIAEEGDDEVRPFADELITIPAVPTLLQPLVSTVPLQVLAAEIARARGYDVDKPRNLAKSVTVE
>NZ_CP040605.1|WP_168585467.1|1881254_1882538_+|helix-turn-helix-domain-containing-protein
MARQSETVVDLRRALGAMLAKQRESARIRQSELARKTHYSRTSISHIEAGRQFPARDFWKKADEICKCNGVLLAEYDAAVAEEASNKVADLFSQQNSASICEQSWFSNVSSDDGDQIEAVELVRRASASDVTSETLDMLEAAFDDLASSYTTTPPNVLIQRVRQHLRYVHKLLDGRMSLADHRRLLVIGGWLSLLGATVHVDLQQDAAATARLRTAASLAREVNHAEIRAWCYETEAWRVLTQGDFARASDLARSAVQLAPGGSSVAIQATAQIGRANARLGQAEETYESIKSVHQMVSPMQRPERPEHHYRYDPDKSLAYTATTLAWLGDSAAEEYAREVIKRLGPTSDSSKWPRRVAAANLDLALALLASDRLDEACATAMRAIASGRVVPSNHWRALEVVKAVESRQLPEARDLREAYEALPRG
>NZ_CP040605.1|WP_168585466.1|1880004_1880982_-|hydroxymethylbilane-synthase
MTDDLRERFADEPLRIGTRTTPLAKAQTQRVVRSIGDCVPGLAIETVGIETSADLWTGDLSLLGGKGNFTKEIDRSLISGKIDIAVHSMKDVPGDVPLPKGTEFGAYLPRGDVHDVVIAREGRQLADLPAGAKVGTSAVRRRAQLTLYRSDLIIERVRGSVNSRIKKMDDGEYDAILLARTGLERVGLDHRITEILPTTWVDGKTPAMVPAVGAAVIGVQARTGDEPVMRLLEELNDPETARHIATERTMLHMLRGHCNSPIAGHAHTTADEQLSLFGMVFNRDGSQWVRSHGWGPIDDPASLGAWVAGDLLRQGARRLITATRK
>NZ_CP040605.1|WP_168585465.1|1879519_1880008_-|NUDIX-hydrolase
MSRTPPAHPGTARGLIRDHDGRWLIVRPVNDLRWHLPGGLIEQNEPPTAACRREVREELGLDLTPGPLYAVGWNAPRRAGSRARYTFIFNMGTHSEDELAQQIRLQQSEIEDWQWSRPDYAAILLHPDMAERLNHARATYPSGYHETAAIRLPKPTTGTSHL
>NZ_CP040605.1|WP_168585464.1|1877664_1879182_-|NAD(P)H-hydrate-dehydratase
MHGVWTPDQIRAAEQRLFARTPEPAVMRRAAYAVSVHTARVLAEVTGGVAGRHVTLLVGAGNNGGDALWAGAFLRRRGVGVTAVLLAPEKAHAAGLAALRRAGGRAVPAEGSSPDTAGIGAEAADAVERADVVIDGIVGLSARGSLRPTAAELVRRVDVPIVAVDLPSGVDPVTGAVNGPAVLADVTVTFGGRKPCHVLGAGAAHSGDVEVIDIGVADELPEPELYLLQAAEIGAGWPVPGPADDKYSQGVVGVAAGSATYPGAAALASGAAVQATAGMVRYAGPAADVVRMRWPEVVATGSVTDAGRVQAWAVGPGIGTGASGRDVLRHVLESGLPVCADADSITLFADDDTLWDARDPDAPLVLTPHAGEFARLSGAELGEDRVSAAREVAERFDAVVLLKGNTTVVAAPDGRVLVNDSRHAWPATAGSGDVLTGLIGALLASGVEPWLACGYAAHVHARAADLAAHGAPTRTPSEVGAPIGASALLAAVPTAIRAIREAALP
>NZ_CP040605.1|WP_168585463.1|1876198_1877344_-|alanine-racemase
MSDQPAYRADLRIDVGAIRHNVKVLSARARSSGARTMAIVKSDGYGHGAVTVAAAALESGADGIGVASIGEALQLRAAGITAPVLCWLYVEDDDFAPAVAADIELSASSQTSLGRIAAAAEQQGRVARVHLKIDTGLCRNGCPAELWPALVEAAAKAEADGHVEVMAVWSHLACADELDHPSIDRQAERFQRAYEQAREAGLNPIRHLANSAAVLTRPDLHFELVRPGIAVYGLDPVPQHGDHDLRPAMTFRSSVALTKRIAAGEAVSYGQSWTAERPTNLALVPVGYADGVPRTLSGRISVWLAGKRRPVVGRVCMDQLVVDCGDDEVREGDEVLLFGPGDRGEPTAAEWADEIGTIHYEIVTGMYRPRVTRTVVDAEAS
>NZ_CP040605.1|WP_168585473.1|1890121_1890319_-|hypothetical-protein
MIFQILIVIVVSALAGAGGGALVAMIAKNKAPAQPPLQQFPPPQQGFSPPPQQGFGPPPQGPYQQ
>NZ_CP040605.1|WP_168585474.1|1890533_1890677_-|hypothetical-protein
MRGRVFGDLLIVLVVPLVLMVLGAFVLAVVLAQGWGLHLIFEGGGLY
>NZ_CP040605.1|WP_168585475.1|1890686_1890845_-|hypothetical-protein
MGAIVVAMVVGLVAVGLVVAIVIFSALALAGMKAVNAAHESRSWFVNRRGRS
>NZ_CP040605.1|WP_168589911.1|1890896_1892231_-|phosphoglucosamine-mutase
MARLFGTDGVRGLANADLTPELVMSVAAAAARVLYDRDDSQRRVALVGRDPRASGEMLEAAVTAGLTSAGAHVLRVGVLPTPAVAHLVAELGAHLGVMISASHNPMPDNGVKLFGAGGHKLPDAVEDEIEARLTEQVDRPTAAHVGRVRDVPDAVRRYVDHLLTAAPQSLEGLKVVVDCANGAASVAAPEAYRRAGAEVIAINAEPDGININDGVGSTHLGVLQAAVLEHGADLGIAHDGDADRCLAVDASGAAVDGDQIMAILAVAMHESGELTDNTLVATVMSNLGLHLAMREQGVELRTTAVGDRYVLKELRAGGFALGGEQSGHVVLPGHATTGDGLLTALRLMGRMSATGTPLASLAKVMRRLPQVLINVRVADKAAAVAAAEVASAVAAAEGELGDTGRILLRPSGTEQLVRVMVEAPSEETAQAVAERLAEIVAAIR
>NZ_CP040605.1|WP_168589912.1|1892482_1892986_-|30S-ribosomal-protein-S9
MTPEETAEVASEETVEVDETAGVEETAEAVAPAPIPVPTGRPVQTVGRRKEAVVRVRLVPGNGGFKLNGKSLEQYFPNKVHQQLIKEPLVTVERVESFDVLATLHGGGPSGQAGALRMAIARALVAYEAEDRPALKKAGMLTRDAREKERKKYGLKKARKAPQYSKR
>NZ_CP040605.1|WP_010316190.1|1893012_1893459_-|50S-ribosomal-protein-L13
MRTYSPKPGEVTRAWHVIDAEDVVLGRLATQAATLLRGKHKPTYAPHMDTGDFVVVVNAEKVALTGNKRTQAFQYRHSGYPGGLRKQSFGEVLEKHPERLLEKAIKGMLPKNKLGRAMGKKLKVYAGPEHPHQAQNPQPFEINAKVEK
>NZ_CP040605.1|WP_168585476.1|1893827_1894118_-|WXG100-family-type-VII-secretion-target
MSEIAVNFAELQQASDDLQAAAQKIQSELDDLEGKIQKLVSTWEGEAVAAYQDAQKSWDEEAARMQETAAKMGMAVAAANESFQAGEKKNAGRFGG
>NZ_CP040605.1|WP_168585477.1|1894180_1894492_-|WXG100-family-type-VII-secretion-target
MAGIGADVEAIEKASQDIDEARNAVEQALQQLSGQLEGPVANWKGAAADVFRKLMGSYEDSGKKILQKLDELGQNVQSSGADYAQVQEDQAQEISKISAMLDG
>NZ_CP040605.1|WP_168585478.1|1894630_1894984_-|hypothetical-protein
MADPADSVRRFRAELADAVGRSRRARDEAHHRAEVFQRHTTELAKNAATGSSAAESVQRAVAIDYRTRVGLEVPEYSAIESNVRPDTAANESAAGKSQEQTPSDGSDLDFSQAQIMR
>NZ_CP040605.1|WP_168585479.1|1895048_1896878_-|type-VII-secretion-associated-protein
MSLHVSIDFGTSSTCTVVSVGGAEPQVVVIDGQPLVPSAVFAAADGTLFVGHEAERQAAVDPARFEPHPKRRIDEGELLLGSSVLKVVDVIRAVLQRAVGEARRFAGGAAVDLLVLTHPADWGAMRTAELRKAATGLGKELVMVPEPVAAAVFHSAGHGLPDGGALAVIDLGGGTVDASVVRKQGSSFQVLATRGEPNFGGADIDQALLDHIGRLVSATDPEAWRRLVEGRDMADRRRRRVLRQDVRGAKETLSRHTYTDVPMPPPFSDAHVTRVDLEALIAGPLGKSADLVLATLREGKVQRQQLAGVFLVGGSSRIPMVARLIHERTGVVPTTLDQPETVVARGALRAVRLDPDRSGGLAPAGAWAGASTVRAYPVPGPPPVGSAGGSPVGPGVTAGDSLSGARTVVIGGSDQTMPVAHRPSRKKRKLPWLIGAGVAVVVAVGVVLTLVITSSGQPQAEPGGPTRRAAQYDYEFSYPGDWKQIGGDPNNWQTLIAPEDDAQDSVIAVNEGKLDFDTDTDRNRAVQQLLSDYQQKVAAGEPFSLFNPSTSFAGRDVVYYRQQMPDATVEWYVLHRRQFRVLVGCKYGSVGKDDVVRACEQVVGSIKVR

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Crispr_ID: NZ_CP040605_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_11

2607685-2607937

Orphan

Consensus_repeat	Method
CCTGCGGTTGTTGCTGCGGGAATCC	CRISPRCasFinder

4 spacers

The CRISPR arrays of NZ_CP040605_11

>merge|NZ_CP040605|11|2607685-2607937|CRISPRCasFinder
GTTGCGGCTGCTGCTGCGGGGTGGCCTGAGCGGCAGCGTCTGCCCAGCTGAACGCCGGCGGGAACGGGTTGGGCTGCTGCGGGAATCCGCCGGACTGCGGGCCTGCCTGCGGCTGCTGCTGCGGGAATCCGCCCGAGGAAGGCCCCACCTGCGGTTGTTGCTGCGGGAATCCACCGGGCGGCGGCCCCGCCTGCGGTTGCTGCGGAAACTCGCCGGATGGCGTGCTCGCCTGTGGTTGTTGCTGCGGGAATCC

>NZ_CP040605|11|10|2607685-2607937|CRISPRCasFinder
GTTGCGGCTGCTGCTGCGGGGTGGC	CTGAGCGGCAGCGTCTGCCCAGCTGAACGCCGGCGGGA
ACGGGTTGGGCTGCTGCGGGAATCC	GCCGGACTGCGGGCCTG
CCTGCGGCTGCTGCTGCGGGAATCC	GCCCGAGGAAGGCCCCA
CCTGCGGTTGTTGCTGCGGGAATCC	ACCGGGCGGCGGCCCCGCCTGCGGTTGCTGCGGAAACTCGCCGGATGGCGTGCTCG
CCTGTGGTTGTTGCTGCGGGAATCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168586001.1\|2593679_2595488_+\|gamma-glutamyltransferase-family-protein	unknown	unknown	gnl\|CDD\|223482
NZ_CP040605.1\|WP_168586008.1\|2608285_2610040_+\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224748
NZ_CP040605.1\|WP_168586014.1\|2613534_2613972_+\|DUF983-domain-containing-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586015.1\|2614343_2615498_-\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|275041
NZ_CP040605.1\|WP_168586010.1\|2610828_2611080_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586013.1\|2612758_2613349_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NZ_CP040605.1\|WP_168586009.1\|2610061_2610730_+\|peptide-methionine-(S)-S-oxide-reductase-MsrA	unknown	unknown	gnl\|CDD\|234604
NZ_CP040605.1\|WP_168586005.1\|2600676_2601576_-\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|273359
NZ_CP040605.1\|WP_168590004.1\|2602974_2603235_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133388
NZ_CP040605.1\|WP_168586002.1\|2597496_2598555_+\|sugar-nucleotide-binding-protein	unknown	unknown	gnl\|CDD\|187573
NZ_CP040605.1\|WP_168586016.1\|2616025_2616364_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586003.1\|2598551_2599835_+\|aspartate-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|227325
NZ_CP040605.1\|WP_168586000.1\|2591940_2593251_+\|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|223936
NZ_CP040605.1\|WP_168590002.1\|2595614_2597126_-\|flavin-monoamine-oxidase-family-protein	unknown	unknown	gnl\|CDD\|224152
NZ_CP040605.1\|WP_168586012.1\|2612235_2612646_-\|PPOX-class-F420-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274679
NZ_CP040605.1\|WP_168586011.1\|2611330_2611540_+\|dodecin-domain-containing-protein	unknown	unknown	gnl\|CDD\|377810
NZ_CP040605.1\|WP_168586006.1\|2603352_2606595_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133029
NZ_CP040605.1\|WP_168590003.1\|2601874_2602987_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376270
NZ_CP040605.1\|WP_168586017.1\|2616360_2616570_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586004.1\|2599836_2600334_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|176870

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168586001.1\|2593679_2595488_+\|gamma-glutamyltransferase-family-protein	gnl\|CDD\|223482	COG0405, Ggt, Gamma-glutamyltransferase [Amino acid transport and metabolism].	3.41201e-133
NZ_CP040605.1\|WP_168586008.1\|2608285_2610040_+\|acyltransferase-family-protein	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	5.59664e-26
NZ_CP040605.1\|WP_168586015.1\|2614343_2615498_-\|methyltransferase-domain-containing-protein	gnl\|CDD\|275041	TIGR04188, conserved_hypothetical_protein, methyltransferase, ATP-grasp peptide maturase system. Members of this protein family are predicted SAM-dependent methyltransferases that regularly occur in the context of a putative peptide modification ATP-grasp enzyme (TIGR04187, related to enzymes of microviridin maturation) and a putative ribosomal peptide modification target (TIGR04186).	2.90436e-121
NZ_CP040605.1\|WP_168586013.1\|2612758_2613349_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	2.35937e-17
NZ_CP040605.1\|WP_168586009.1\|2610061_2610730_+\|peptide-methionine-(S)-S-oxide-reductase-MsrA	gnl\|CDD\|234604	PRK00058, PRK00058, peptide-methionine (S)-S-oxide reductase MsrA.	3.63227e-143
NZ_CP040605.1\|WP_168586005.1\|2600676_2601576_-\|EamA-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	1.97326e-21
NZ_CP040605.1\|WP_168590004.1\|2602974_2603235_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133388	cd01282, HTH_MerR-like_sg3, Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily. Putative helix-turn-helix (HTH) MerR-like transcription regulators (subgroup 3). Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	2.64077e-11
NZ_CP040605.1\|WP_168586002.1\|2597496_2598555_+\|sugar-nucleotide-binding-protein	gnl\|CDD\|187573	cd05263, MupV_like_SDR_e, Pseudomonas fluorescens MupV-like, extended (e) SDRs. This subgroup of extended SDR family domains have the characteristic active site tetrad and a well-conserved NAD(P)-binding motif. This subgroup is not well characterized, its members are annotated as having a variety of putative functions. One characterized member is Pseudomonas fluorescens MupV a protein involved in the biosynthesis of Mupirocin, a polyketide-derived antibiotic. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.45446e-42
NZ_CP040605.1\|WP_168586003.1\|2598551_2599835_+\|aspartate-aminotransferase-family-protein	gnl\|CDD\|227325	COG4992, ArgD, Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism].	2.14373e-135
NZ_CP040605.1\|WP_168586000.1\|2591940_2593251_+\|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	gnl\|CDD\|223936	COG1004, Ugd, Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane].	0
NZ_CP040605.1\|WP_168590002.1\|2595614_2597126_-\|flavin-monoamine-oxidase-family-protein	gnl\|CDD\|224152	COG1231, COG1231, Monoamine oxidase [Amino acid transport and metabolism].	9.99662e-91
NZ_CP040605.1\|WP_168586012.1\|2612235_2612646_-\|PPOX-class-F420-dependent-oxidoreductase	gnl\|CDD\|274679	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomyces, make F420. The Partial Phylogenetic Profiling algorithm identifies this members of this protein family as high-scoring proteins to the F420 biosynthesis profile. A member of this family, Rv1155, was crytallized after expression in Escherichia coli, which does not synthesize F420; the crystal structure shown to resemble FMN-binding proteins, but with a recognizable empty cleft corresponding to, yet differing profounding from, the FMN site of pyridoxine 5'-phosphate oxidase. We propose that this protein family consists of F420-binding enzymes. [Unknown function, Enzymes of unknown specificity].	1.37117e-33
NZ_CP040605.1\|WP_168586011.1\|2611330_2611540_+\|dodecin-domain-containing-protein	gnl\|CDD\|377810	pfam07311, Dodecin, Dodecin. Dodecin is a flavin-binding protein,found in several bacteria and few archaea and represents a stand-alone version of the SHS2 domain. It most closely resembles the SHS2 domains of FtsA and Rpb7p, and represents a single domain small-molecule binding form.	2.061e-32
NZ_CP040605.1\|WP_168586006.1\|2603352_2606595_+\|glycosyltransferase	gnl\|CDD\|133029	cd04186, GT_2_like_c, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	5.42915e-49
NZ_CP040605.1\|WP_168590003.1\|2601874_2602987_+\|hypothetical-protein	gnl\|CDD\|376270	pfam18851, baeRF_family8, Bacterial archaeo-eukaryotic release factor family 8. Bacterial family of the archaeo-eukaryotic release factor superfamily. Likely to play roles in biological conflicts or regulation under stress conditions at the ribosome.	2.39321e-59
NZ_CP040605.1\|WP_168586004.1\|2599836_2600334_+\|hypothetical-protein	gnl\|CDD\|176870	cd08861, OtcD1_ARO-CYC_like, N-terminal and C-terminal aromatase/cyclase domains of Streptomyces rimosus OtcD1 and related domains. This family includes the N- and C- terminal aromatase/cyclase (ARO/CYC) domains of Streptomyces rimosus OtcD1 and related domains. It belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. ARO/CYC domains participate in the diversification of aromatic polyketides by promoting polyketide cyclization. They occur in two architectural forms, didomain and monodomain. Didomain aromatase/cyclases (ARO/CYCs), contain two ARO/CYC domains, and are associated with C7-C12 first ring cyclized polyketides. Streptomyces rimosus OtcD1 is a didomain ARO/CYC. The polyketide Oxytetracycline (OTC) is a broad spectrum antibiotic made by Streptomyces rimosus. The gene encoding OtcD1 is part of oxytetracycline (OTC) gene cluster. Disruption of this gene results in the production of novel polyketides having shorter chain lengths (by up to 10 carbons) than OTC. Monodomain ARO/CYCs have a single ARO/CYC domain, and are often associated with C9-C14 first ring cyclizations, these latter domains belong to a different subfamily in the SRPBCC superfamily.	3.79338e-13

>NZ_CP040605.1|WP_168586006.1|2603352_2606595_+|glycosyltransferase
MDKRLIDWTGERCVPWTDDVQVVYEHYHRYALAARFVRGKRVLDLACGEGYGAALLAAEGAEVVGVDIDPTTVEHAQHNYGSRDVSFQVGSITDPELLADAKPFDVIVCFEAIEHVEDHDAILSLVRSRLVQGGLFLSSTPDTAVYSHEHGNDNPYHVKELTAKQYETLLEDAFRHVAVLKQNVTVGSLLTPADHGDPDTAIEGVRLQTIEGRDGEWAVRQGVPHTYLLGIASDKHLPKLPAAALLTDADLTLIRRGGDVTPIIEQRDAAVADVAKLHELYQRSRVESEELKSTISRLEELRKAEEQRADQGVREQAKLRAELDRVGGELHESQQSAERDAARIEWLRDTVARLEGRVADAERQAAELGAANAELAAQNSALVQRAVAKYRKVVERVAPRGTARRDAYEIALGRKPGVPQAEEAVETGPLPVPHSDKPLVSVIVPVHGKWPYTRQCLRFLGGHVVSVPFEVIVVDDASPDDSAEKLAACEGVRLVRAERNLGFIGACNLGAEHARGEYLFFLNNDAEVTESWLDILMDTIRGDERIGLVGAKLVYPDGRLQECGGIVWSDGNGWNYGRNTEPGGAEFNVVRDVDYCSGAAILVRTNVFRQVGAFDTRYAPAYYEDTDLAFAVRAAGYRTVVQPKAVVVHHEGVSNGTDLSTGVKKHQELNRKVFVEKWADTLAAEHLPQASPRNLWLARQRGTRGHHGPIVLVKDHQVPRPDFDSGSVRIRRVLEQFVRLGCRVVFFPGNHARLEPYTTQLQQLGVTVLPEPELQQAFLHEAGSEISLALLSRPQVAWSLVEELRTCAPQAVIAYDTVDVHFLRLERQAEVAEQQGDPARAEALRRKAFASRQMELGLTRSCDVTLVVSEAERVLLRELVPDADVRVLSNVHEVDWSPAKPDGRKDLLFVGSFDHPPNVDAVRWAVREIMPLVREKCPDAVLHVVGSNPTDEVRELAGRGVQVHGWVADLEPQYAASRVTLAPLRFGAGVKGKVGESLSLGVPVVGTTVAIEGMHLVNGEHVLVADDAEGLAEAAVRLLTDDDAWQRLAEAGKAGIAAQFGPDVSRAALGDLLATTDYEA
>NZ_CP040605.1|WP_168590004.1|2602974_2603235_-|MerR-family-transcriptional-regulator
MSAKTGVSVRKLRYHDEQQPLASKRSPGGQRTYPESVVERDRINRQISGLVSTRDRLDDTIGRPPPPGARAALPPARPLNGAGQGR
>NZ_CP040605.1|WP_168590003.1|2601874_2602987_+|hypothetical-protein
MLHTDIPTRTQVDALLTAREPVSVSLYVPTGPASSGDAERIELKNLAGQAIEQLRRAGTAKEDIAGVTEHLADLADDEEFWRFQARSLALFATPKALTTFRLPNHLNAAVEVSDRFHLKPLLRSITFPQTALVLALAQNSVRLVEVVPEMDPVIVDVPGMPADVASSVGKESVTDRLPRRRFQGSEGQKLRMRQFARQVDRAMRPVLRGDVPLILAATEPLQSIFRSVSTASELAPVGLTGNPEESSDRELASVARDVLDDLHAERLRELHRLFERRTGQGRTVADIADVARHATMGAVDTVFVDIDNAVPGFIDEAGAVTFEEADDAVSYGVVDEIARRVWLTGGRVLAVRRDDIPGGGETAAILRYRP
>NZ_CP040605.1|WP_168586005.1|2600676_2601576_-|EamA-family-transporter
MSDQLLTAPARARSFLSGPLPVLLAAVLWGTTGTAASFAPAGASPLSIGAATMGIGGILLLAVAGRSALPVLRSGRTGLLVVGALAVAVYPLAFYSSMALAGVAIGTVVTLGSAPVFAAILERVVDGVRLDRRWALAAAVSVLGLLLITGGGEAGVGTDAVLGALLGLLGGAAYVVYSWAAARMMRGGHGSRAVMGAMFGTGAVVLLPVLAFTGGPLFGSASGLVVAGYLAVIPMGLAYVLFGAGLRRTSTSVATTLSLLEPVVAALLSVLVVGERLGVASWCGVGLIGVGLVLVSTRR
>NZ_CP040605.1|WP_168586004.1|2599836_2600334_+|hypothetical-protein
MPTVTVESLVPGAIGTDADTVFSVLCDTERFADQTDEVRSVTVTARQEGTQDSEWAVTFRNGILCWSERDQIDHSARTITFWQLDGDFERFDGEWAVDEFGSDTVVRFTAHFDLGMPSLAAIIDPIAEGALRASIKSILRGLLGEELVFLDTASYPVAPDAERPS
>NZ_CP040605.1|WP_168586003.1|2598551_2599835_+|aspartate-aminotransferase-family-protein
MSGHGTQHSGSRQTSERYRRHISRGRARLADMTGGLTEVSSHGSRVVDAAGKTHLNCGGYGVFLLGHAHPTVVEAVVEQVRRHPLTTRLMLEPTVASAAETLARVAPSGMDYVHFVNSGAEATEAAIKLARAHGHAHLISAVGGYHGKTMGALSITARELYQAPFRPLLPSVDHVPFGDAQALEEALAAAPPACVVVEPVQGEGGVVVPPSGYLRDVAQLCRKYGALFVLDEVQTGLGRLGHWWGADRESVTPDILLVGKNLSGGVVPVAAMVATAEAYSPFNRDPFLHTSTFAGSPIAAAAAEAAIRVVVAENLVTKASELGEYLLQELRRILLHHCGHLITDVRGLGLLIGVELVNEQVTGELLMELLDHGVLVNHSLNAHRVLRFTPPAVLTSEDVHWLLEAVTRAAETLARRCPPNAVLEGIP
>NZ_CP040605.1|WP_168586002.1|2597496_2598555_+|sugar-nucleotide-binding-protein
MSQPKFVLLTGASGVVGTALRPALAHHRVISLTHRAKIDSESVIGDVTQPFLGLDELTYQRLVSQVDTVVHCAAKTDFGAGAEAAHQLNVVGTKRVLEFAADAQARVIYVSTAFVARSELTRSAQGLMSEGAARPENYLDSKREAEELLRGSGVPVVIARPSVVVGDSVTGAMANFQGVHLVAAGILRSKFPLLPFAPEELVDVIPQDLLAAGLRALVDADVRGGEYWLTAGPHALTSRRFVDQCVAVAEESGIDVTPPRLVSPDMVDRLIRPVLTDVLSPSARKQFDDLLAMAALFAGAEPFPTSFGALPGNPAALTLPSAEWFESAFRTSVRFFARTKRLVPAAAAGATV
>NZ_CP040605.1|WP_168590002.1|2595614_2597126_-|flavin-monoamine-oxidase-family-protein
MNRFTRRGLLAGVAAAGTGALTAPGAPRAIAQSTPAAGRSETQVVVVGAGLAGLTAARELVAAGCEVLVVEARDRVGGRTVNQAVTAPGASPGTIVEVGGQWVGPTQDRVLGLIQQLGLETFKTYDAGDYADYHNGKLTRYGHVFPADPLNLGLNRIPPSDPVGAAEAAVAIQELDRMAAGVPLDAPWTAHDARTSDGQTFEDWMDHHLVQPGAKSLISLAINAVFSVEPRDVSLLHVLFYIASAGGLDRLLRTSDGAQDSRIIGGSQRISLEMARELGPRVLLNAPVTRIDQDSAGVSVHGDDFSVRAKRCVVTAPPALAARIRYAPLLPGTRDQLTQRMPMGSVIKVQCVYPTPFWRADGLAGQATSDTGLVRTTFDNSPPDASVGVLLGFIEGEQGRHADQMPAAQRRKGVIECFTRYFGERAADPLEYIEKNWLEEEWTRGGYGGVFAPGAWLDFGKALRAPVGHIHWAGTETATIWSGYMDGAVRSGERVAKEVTSSL
>NZ_CP040605.1|WP_168586001.1|2593679_2595488_+|gamma-glutamyltransferase-family-protein
MFTTRPELAGTHGMVAATHWLASAAGMAVLEDDGNAFDAAVAAGFVLQVVEPHLNGPGGEVPALFTTAGDQRPRALCGQGPAPAAATIGHYRDELGLDLVPGTGFLATTVPGAWDGWLLLLRDHGTKTLREVLKYAIGYARGGFPIVDRISTTIDTVRDMFAEHWPTSAQLWLTGGAAPKPGSVLKNPALADTWERLLAEGEAASPGREAQIDAARRAWSHGFVAEAVEKFVRTPHRDNSGRDHAGVITAQDMAEFEAGYEAPLTVDLPGGWTLAKFGIWSQGPALAQQLRILEGLADRINYVDGVADADTVHIAVEAAKLAFADREAWYGDSADPGVLDDLVSRDYAAARRALIGDRASLELHPGSPGGRNPILPAHVAEGRGVDGLKDPSGVGIGEPTVSPSGESRGDTVHVDVVDRWGNLISATPSGGWLQSSPVIPELGFCLGSRAQMFWLDRDLPNSLAPGKRPRITLSPSLALRGGVPTMAFGTPGGDQQDQWQLCFWLAHVHCGLNLQEAIDAPAWHTGAFPGSFYPRAWEPGRVVAESRLGAETLAELGRRGHDVLDAGPWALGRLSAVSRDPDTGLLRAAANARGAQGYAAGR
>NZ_CP040605.1|WP_168586000.1|2591940_2593251_+|UDP-glucose/GDP-mannose-dehydrogenase-family-protein
MFARRIVVVGTGYVGLTTGACLASLGHRVVCSDVNTAKVEQLSRGEVRIHEPGLAELVQEGIAAGRLEFVVGSAGAVAEAEVVFLCVPTPMGAGGEADLAVVEAVAHEVRELLPAGCVLVTKSTVPVGTSARLRELVGREDVPVVSNPEFLREGSAVHDFLNPDRIVVGSDSQDAAERVAALYARLGAPTVLTDAASAEMVKYAANCFLATKLSYVNAIAELCERLGADISDVTEGMGYDRRIGQSFLQPGPGWGGSCLPKDTAALLQVAEAVDFDFPLLQATISSNARQRERMVVKVVEACGGSLDGVRLGLLGLTFKAGTDDLRDSPALEVARLLAARGAELVAYDPGLRGDEPALPPEVELVDDPYQAAKEAAVLVLLTEWQEFRTLDWNRVAEALQGPVVVDTRNHLDPDVLRRAGLSWRGVGRTPVAGGPA
>NZ_CP040605.1|WP_168586008.1|2608285_2610040_+|acyltransferase-family-protein
MIWVGDVRVVHTHPEWFAEPNHGFAWIRMIGALAVIYGHSSPLAGTGDLFPADWPVQPDEGVLMGFFAMSGFQITESWIRDPHPFRFAAKRILRLWPPMLTVSLTMALIIGPMITTLSVGDYFAANGTWGYVVNNAGLLTLRHELPGVFVNNPWPNAVNGSLWTLPMELLAYAALYALLLLGAGKHKYRWLAVVALIGIITWDRYLEELPGSESAGSFLSVPVESLVAFLVAFAFGVVLNLYRVPLSPLAAGGGLVLLVLMPNSITGSFWMTFAVSYAVVVTGHFWPSRLTVPGVWVNGSYGVYVWSFPIQQLLAMAGIRNQWLMLICAAPLAYCVGTLSWKFIEEPTMKLRHYLTPASKKKEPERAEDGLDEPEDLDDSEDPDDFDDLEPEDRDERDDDRAARLDDPDEPRAARRATTMRRPPPRPPAPNRDGAAQEPPTKLTPVRPGADQTRPPRPLRRATTPPNGAPVDHNRVNGVPRHGSADGPNAARLNGLPMNGTGPPLGRPSARSRRSAEQWAVGPPAVPPEDSVLSKRLSGDLDFDRTPVDRQAVRRTGGRHARPEPPPTPEEETRPVRPKRQDRP
>NZ_CP040605.1|WP_168586009.1|2610061_2610730_+|peptide-methionine-(S)-S-oxide-reductase-MsrA
MALFGDKTRLIDPAEALPGRSNPLPVAESHAVFPDRRIMPPFPEGYATAVVGMGCFWGAERTFWRTEGVWSTAVGYAGGFTPNPTYEEVCSGLTGHTEAVLVVFGPAAISYQQVLKVFWENHDPTQGMRQGNDIGTQYRSAIYYADDQQKAEAEASAQAFQKALAEAGLGQVTTEIAPLKTFYYAETYHQQYLSEAKNPNGYCGLGGTGVSCPIGLGVPGER
>NZ_CP040605.1|WP_168586010.1|2610828_2611080_-|hypothetical-protein
MRRFIVGVLFTGLCGLGSAGIAAAEEVPFDPAPLLQQVTSQDATSGQNGTSEQGASASSSAHSDDGSPAQAHAQGQDAQGQDG
>NZ_CP040605.1|WP_168586011.1|2611330_2611540_+|dodecin-domain-containing-protein
MTDHVYRVTEVVGTSTKGVDDAIKKAIARASQTLRNIDWFEVENVRGHVEDNELAHYQVTLKIGFRLET
>NZ_CP040605.1|WP_168586012.1|2612235_2612646_-|PPOX-class-F420-dependent-oxidoreductase
MDLDEAREVIGNQHRAVLSTLRADGTPQMTPVLTTTDSAGHVTVSTVAGAAKVRNLRRDPRAWLCVLPDQFFGRWIQVEGIVEIVELPAALPLLEEYYRRISGEHEDWAAYRQAMQEEHRVLLRITPTRAVSSPTR
>NZ_CP040605.1|WP_168586013.1|2612758_2613349_+|sigma-70-family-RNA-polymerase-sigma-factor
MGEDVAGGPLPDDRVLLARLRAGDDLAYGDLYRRHAPVVRRFALSMPHPGIDVDDVVAEVFLRTLRAVRAGHGPRDAIRTYLSTVVRRVLWEWAAARRDELMNGDELGEHAARQRDHQSVQAEGELLARAFHRLPVRWREVLWWTEVEGHRPASLAGQLGLTPNATAVLAHRARRGLREAYQQAAELPVAGCLRRA
>NZ_CP040605.1|WP_168586014.1|2613534_2613972_+|DUF983-domain-containing-protein
MNRVVRGSDGREWTIKASLEWSNPIAADEFEHDVNGGSAPAILMGALFLFLVVMFVVWTPAEVYVPKWLILLLIVGVLFFPVRWVLRRPWTVTAATPGDHDENPPETWVGVVRGFFDVRQEISLVARHIELYAEPDMNGGLQPVE
>NZ_CP040605.1|WP_168586015.1|2614343_2615498_-|methyltransferase-domain-containing-protein
MTTTTETEALRAQLVAQLTDDGYLRDPAWISAFSETPRGLFVPYYFEPRSDRPGWRLLERTDEWRDGVYRNAAHVTQIGNNPDALNDARRGETVTGQPTSSSSAPSLMALMLEALDVHDGHRVLEIGTGSGYNAALLCHRLGSERVATVDVDPVLVDFARDRLAKLGHAPQLAAVDGRDGCPEHAPFDRIIATVGVKRIPAAWIDQTRPGGIILAPLTVGGLLAVLTVDHDGRAEGTFLPDAGMFMPTRDKQIPDATIPHRDAAATEPETTSLAVDVAAGREFEFFAALHTGPYSRIGFTSTDGSPPETWLIRPDGSWACHTTPEPGRHLVRQGGPARLWDTIEHAHQQWQALGSPARERFGLTIDAGKHHVWLDEPPNEVIDL
>NZ_CP040605.1|WP_168586016.1|2616025_2616364_-|hypothetical-protein
MIAAMVASGLLGVGGLALWATFYYAPARHAGSGEGALTVAYLVARVEAETCGHGRHRLREPVVMRGDLADALALEETRMLPLVETGLPLDDREAMARHPGMLRRLLAALQNL
>NZ_CP040605.1|WP_168586017.1|2616360_2616570_-|hypothetical-protein
MSAEHAHIGRMIRATVLMLGYAADDVERGRWSDDEIRQLGDQLAMVTAALRGDGKPPEPLVIDLSEAKR

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Crispr_ID: NZ_CP040605_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_12

3302147-3302279

Unclear

Consensus_repeat	Method
CCGCAAGTTCCATTGAAATCGAAGGTCCGATTTCCAT	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NZ_CP040605_12

>merge|NZ_CP040605|12|3302147-3302279|CRISPRCasFinder
CCGCAAGTTCCATTGAAATCGAAGGTCCGATTTCCATTTGAAATTGCGGAAGTTGTCCACAGCTGCCGGCGTGTCGGGGGCTGACGCGCCGGAGGGCCGCAAGTTCCATTGAAATCGAAGGTCCGATTTCCAT

>NZ_CP040605|12|11|3302147-3302279|CRISPRCasFinder
CCGCAAGTTCCATTGAAATCGAAGGTCCGATTTCCAT	TTGAAATTGCGGAAGTTGTCCACAGCTGCCGGCGTGTCGGGGGCTGACGCGCCGGAGGG
CCGCAAGTTCCATTGAAATCGAAGGTCCGATTTCCAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168586518.1\|3307395_3309087_+\|BCCT-family-transporter	unknown	unknown	gnl\|CDD\|376718
NZ_CP040605.1\|WP_168590089.1\|3302313_3303480_-\|PQQ-dependent-sugar-dehydrogenase	unknown	unknown	gnl\|CDD\|369642
NZ_CP040605.1\|WP_168586517.1\|3303665_3307256_+\|transcription-repair-coupling-factor	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|224118
NZ_CP040605.1\|WP_168586511.1\|3293620_3294256_+\|NAD(P)H-binding-protein	unknown	unknown	gnl\|CDD\|225462
NZ_CP040605.1\|WP_168586523.1\|3313402_3313780_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NZ_CP040605.1\|WP_168586512.1\|3294393_3295008_+\|malonic-semialdehyde-reductase	unknown	unknown	gnl\|CDD\|180040
NZ_CP040605.1\|WP_168590069.1\|3288309_3289014_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|366760
NZ_CP040605.1\|WP_168586520.1\|3309906_3310854_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372652
NZ_CP040605.1\|WP_168590088.1\|3298041_3299757_-\|diguanylate-cyclase	unknown	unknown	gnl\|CDD\|143635
NZ_CP040605.1\|WP_168586514.1\|3296170_3297688_-\|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	unknown	unknown	gnl\|CDD\|184641
NZ_CP040605.1\|WP_168586515.1\|3300367_3301336_+\|acyl-CoA-desaturase	unknown	unknown	gnl\|CDD\|224316
NZ_CP040605.1\|WP_168586524.1\|3314055_3315342_+\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP040605.1\|WP_168586509.1\|3291966_3292542_-\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|235457
NZ_CP040605.1\|WP_168586513.1\|3295160_3296147_-\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|179535
NZ_CP040605.1\|WP_168586525.1\|3315345_3315882_+\|septum-formation-initiator-family-protein	unknown	unknown	gnl\|CDD\|368217
NZ_CP040605.1\|WP_168586510.1\|3292630_3293233_-\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	unknown	unknown	gnl\|CDD\|235534
NZ_CP040605.1\|WP_168586522.1\|3312133_3312913_+\|murein-transglycosylase	unknown	unknown	gnl\|CDD\|225501
NZ_CP040605.1\|WP_168586521.1\|3310992_3312009_+\|MazG-family-protein	unknown	unknown	gnl\|CDD\|237065
NZ_CP040605.1\|WP_168586519.1\|3309268_3309814_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586516.1\|3301509_3302103_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168586518.1\|3307395_3309087_+\|BCCT-family-transporter	gnl\|CDD\|376718	pfam02028, BCCT, BCCT, betaine/carnitine/choline family transporter.	0
NZ_CP040605.1\|WP_168590089.1\|3302313_3303480_-\|PQQ-dependent-sugar-dehydrogenase	gnl\|CDD\|369642	pfam07995, GSDH, Glucose / Sorbosone dehydrogenase. Members of this family are glucose/sorbosone dehydrogenases that possess a beta-propeller fold.	4.15779e-86
NZ_CP040605.1\|WP_168586517.1\|3303665_3307256_+\|transcription-repair-coupling-factor	gnl\|CDD\|224118	COG1197, Mfd, Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription].	0
NZ_CP040605.1\|WP_168586511.1\|3293620_3294256_+\|NAD(P)H-binding-protein	gnl\|CDD\|225462	COG2910, COG2910, Putative NADH-flavin reductase [General function prediction only].	7.86875e-60
NZ_CP040605.1\|WP_168586523.1\|3313402_3313780_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	2.48876e-10
NZ_CP040605.1\|WP_168586512.1\|3294393_3295008_+\|malonic-semialdehyde-reductase	gnl\|CDD\|180040	PRK05365, PRK05365, malonic semialdehyde reductase; Provisional.	4.6477e-115
NZ_CP040605.1\|WP_168590069.1\|3288309_3289014_-\|ATP-binding-protein	gnl\|CDD\|366760	pfam01695, IstB_IS21, IstB-like ATP binding protein. This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.	9.00629e-35
NZ_CP040605.1\|WP_168586520.1\|3309906_3310854_+\|hypothetical-protein	gnl\|CDD\|372652	pfam13624, SurA_N_3, SurA N-terminal domain. This domain is found at the N-terminus of the chaperone SurA. It is a helical domain of unknown function. The C-terminus of the SurA protein folds back and forms part of this domain also but is not included in the current alignment.	8.62518e-07
NZ_CP040605.1\|WP_168590088.1\|3298041_3299757_-\|diguanylate-cyclase	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	7.88918e-51
NZ_CP040605.1\|WP_168586514.1\|3296170_3297688_-\|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	gnl\|CDD\|184641	PRK14352, glmU, bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU.	0
NZ_CP040605.1\|WP_168586515.1\|3300367_3301336_+\|acyl-CoA-desaturase	gnl\|CDD\|224316	COG1398, OLE1, Fatty-acid desaturase [Lipid metabolism].	8.94245e-64
NZ_CP040605.1\|WP_168586524.1\|3314055_3315342_+\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP040605.1\|WP_168586509.1\|3291966_3292542_-\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	9.14043e-98
NZ_CP040605.1\|WP_168586513.1\|3295160_3296147_-\|ribose-phosphate-diphosphokinase	gnl\|CDD\|179535	PRK03092, PRK03092, ribose-phosphate diphosphokinase.	0
NZ_CP040605.1\|WP_168586525.1\|3315345_3315882_+\|septum-formation-initiator-family-protein	gnl\|CDD\|368217	pfam04977, DivIC, Septum formation initiator. DivIC from B. subtilis is necessary for both vegetative and sporulation septum formation. These proteins are mainly composed of an amino terminal coiled-coil.	1.83857e-14
NZ_CP040605.1\|WP_168586510.1\|3292630_3293233_-\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	gnl\|CDD\|235534	PRK05618, PRK05618, 50S ribosomal protein L25/general stress protein Ctc; Reviewed.	2.10925e-67
NZ_CP040605.1\|WP_168586522.1\|3312133_3312913_+\|murein-transglycosylase	gnl\|CDD\|225501	COG2951, MltB, Membrane-bound lytic murein transglycosylase B [Cell envelope biogenesis, outer membrane].	1.61066e-28
NZ_CP040605.1\|WP_168586521.1\|3310992_3312009_+\|MazG-family-protein	gnl\|CDD\|237065	PRK12334, PRK12334, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	1.71895e-76
NZ_CP040605.1\|WP_168586516.1\|3301509_3302103_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.26237e-20

>NZ_CP040605.1|WP_168586516.1|3301509_3302103_+|TetR/AcrR-family-transcriptional-regulator
MTGKERRQQLLDVARALFAEKGFDGTSIEEIAHRAGVSKPVVYEHFGGKEGVYAVVVDREMRNLLDLVVSALSAGHPRKLLEQAARALLDYIDNNTDGFRVLVRDSPVASNSGTFSSLLNDIASQVEHILALQFSARGYDSKLAPLYSQALVGMVALTGQWWLEARKPKKEEVAAHLVNLAWNGLSHLEHKPRLSTK
>NZ_CP040605.1|WP_168586515.1|3300367_3301336_+|acyl-CoA-desaturase
MTAATERVAPTEARAESGPKPLTAGTRPWVAQLAVYVFVLVPFLALVLAVPAAWGWGLGWVDIGLALVFYVASGLGVTVGFHRYFTHGSFKAKHGVKIALAIFGMIAVQGPAITWVADHRRHHAFSDREGDPHSPWRFGSSPAALAKGFWHAHMGWLFERDLTNEDRFAPDLLKDEALVKVNRLFPLWTALSLVLPGVLGGLFTWSLWGAFTAFFWAGLVRVSFLHHVTWSVNSICHMIGERPFKSRDKAANFWPLAILSFGESWHNLHHADPTCARHGVLRGQIDISARVIWIFEKLGWAWNVRWSNEKRLARISVTEYKG
>NZ_CP040605.1|WP_168590088.1|3298041_3299757_-|diguanylate-cyclase
MRDDPVATLSEVSDAWLVGRARELNAVGQHSDTASQRGTIREADNLLAEAQRRGEPRIVGQLLRHCASMRLVTPGLVDSADPLLDELLTHTRRHGLDVLLADAHALRSRRALLGGSEDNALTEVAHGLAMLDDELVPDRTLGRRSWERLLATSLIDIGLVLTQLGVYETADEVMTRAHQRIRESGGPHEIAVHMINRCRMLLGWGLRLERIGQHAEATARFTTASAIAVAVEGPWRESLFPRVSDRPAAEQVPVLGAAHALAQPHVEHIKRLEVLRALDRAIHPREKIIVAIALSRCLTRADLGEEAVRVLSDTREETASDTSEPTLRISLAREYAQLIEVGTGGAHDALRDYALELETELWTMRQARLSTLVTRLENSRLIHRHDAITRQALQDPLTGLSNRRALDDRLETLLNAPDAQPLAVALVDLDGFKGVNDRCSHAEGDDVLRTVAMTLRDTLRTDDFVARYGGDEFVVLLPGAALGAAEAALQRTAEAVDRLPGERSRGVTLSIGVVAMRPQESAAQVLARADAAMYQAKRDGGNRVWAFSGVTNDPPDTPAEDHSVWIPPDAV
>NZ_CP040605.1|WP_168586514.1|3296170_3297688_-|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU
MLQGDTAQPSSRSDASPEIVSTIVLAAGEGTRMRSATPKVLHRLAGRPLVEHAVRAAAGVDPDALVVVLGHGRDAVAEHLKGLAGVLDRPIGTAVQEEQLGTGHAVSCGLSDLADGLTGTVLVSYGDVPLLDSDTLRALLAEHRDSGNAVTVLTAVVDEPTGYGRMLRDADGRVTGIVEQKDATPEQTEITEINSGVYAFDAEVLTDALKRLSTDNAQGELYLTDVLSIARDDGRPVGALVCADPWLVEGINDRVQLARLGAELNRRLLLRWMRAGVTIIDPNSVWLDCDVVLERDVLLEPGVQLRGGTTVGEGATVGPDTTLTGCVIHPGASVVRTQGEGAEIGPDAKVGPFAFLRPGTRLGTNGKIGTFVETKNAAIGDGTKVPHLSYVGDATIGEQSNIGAATVFVNYDGVAKHHTVIGSHARTGADNMFVAPVEIGDGAYTAAGSVITQDVPPGAMAVARGKQRNVEGWVARRRPGTAADQASQQALSKAEPTTNPTNDAR
>NZ_CP040605.1|WP_168586513.1|3295160_3296147_-|ribose-phosphate-diphosphokinase
MTVSAMSATPKKSLKLFSGSSHPELAEEVAKQLDVTVTPQSAYKFANGEIFVRYDESVRGCDAFVIQSHCNPLNDAIMEQLIMVDALKRASAKRITVVMPFYGYARQDKKHKGREPISARLMADLFKTAGADRIMAVDLHTDQIQGFFDGPVDHLMAQKLLASYIRDTYAGDQITVVSPDSGRVRVAEKWADDLGGTPLAFIHKTRDPSKPNQVVANRVVGDVEGRLCVLVDDMIDTGGTITKATEQLLAAGAKDVIIAATHAVLSGPAVERLSSCGAKEVVLTNTLPIPEERRFPNLTVLSIAPLVAEAIHQVFEDGSVTSLFDGRA
>NZ_CP040605.1|WP_168586512.1|3294393_3295008_+|malonic-semialdehyde-reductase
MTAIDQTEQLVLGADAQDLLFRDARTANSFSDEPVTDEQVQAIYDLVKWAPTSMNQQPLRIVLVRSEESRQRLLPHLMEGNRAKTEKAPLVAILAADTDFHEKLPQVFPHAEGVKDMFAANDELRLNHANLNASLQIAYFILGVRAAGLAAGPMTGFDAAGINAEFFPEGKRQSLVVVNIGKPGENPWFDRLPRLDYDEVVITI
>NZ_CP040605.1|WP_168586511.1|3293620_3294256_+|NAD(P)H-binding-protein
MRLVLFGATGFAGGKILREARQRGHEVVGVARHVESLAEPKEAGSLHDEKFVLDATAGADALIVAIPGRPMPDGTKLFDAVPTLFAAAARRGLRIGVVGGAGSLRVVDGGPRLIDTPEFPEEFKPEAGAHAEVLAALQEAPAGVDWFYVSPAANFGAHAPGERTGSYRLGGDVLVTDADGDSSISGDDYAIAFVDELERPTHRRQRFTVGY
>NZ_CP040605.1|WP_168586510.1|3292630_3293233_-|50S-ribosomal-protein-L25/general-stress-protein-Ctc
MSEVRIAVEQRTEFGKGAARRTRRAGKIPAVLYGHGSDPKHLSLPSVEFARAIRENGHNAVLTLDVSGGDSELALTKTITTHPIKNYIEHVDLLLVKRGEKVTVAVPVVLSGEAGPGGLVSQEITVVEIEAEALHIPEQLELSIAGAEIGTQFHASDIQLPAGVTLQADPEALVVNVTEAAAAMAEEAPAEAAEGEAEGA
>NZ_CP040605.1|WP_168586509.1|3291966_3292542_-|aminoacyl-tRNA-hydrolase
MSTPDSVALIVGLGNPGPRYAGNRHNIGFLVADELADRIGGKFKAHKAGAEVVEGRLAGARAVLVKPRSFMNLSGGPVAGAVKFYKAPPESLTVIHDELDLPFGTIRLKRGGGENGHNGLRSISKSLGTRDYVRVRFGIGRPPGRMDPADYVLKDFSGTERKELAYFIDVCADAVEAVVTKGLEAAQNQFH
>NZ_CP040605.1|WP_168590069.1|3288309_3289014_-|ATP-binding-protein
MLDTLPDRLSLARQQQFTHVDFLELVLADEVARRENTSAGLRARAAGLDPSMRLDTWEETGAVRYDRQLWNELVSLRFLDGPHGALVLGAVGVGKTHLATALGHIAVRRRRSVHMARADKLFKRLKAARLDNSLDAEIRKLAAVELLIIDDFALKRLDATETTDFYELCVERHQKASTVITSNRDASEWLAMMDDPLLAQSAVDRLTSTCHELVVEGESYRQRQRPRASGGDHA
>NZ_CP040605.1|WP_168590089.1|3302313_3303480_-|PQQ-dependent-sugar-dehydrogenase
MLLPLISGLIGCTGADSTDRPAPASTAAPAPSALRVEIVAAGLEHPWDIGFLPDGTTLVSQRPGRLALLADHRPGALVRPVRADFGDVLAEGEGGLMGLLVHPSFAANRRFLTCQTHQENGTPVDIRLITWRLSEDGSRADRVGNLLTGLPVNRSGRHSGCRLALAEDGALLVSTGDTARPAIAQDRGSLGGKVLRVNIDTGAPLPDNPFIASPNPSERLLYTYGHRNPQGVAPRPGGQVFVAEHGPDVDDEINLLRPGGNYGWDPSRGGTESSYDESVPMTDLRRFPDAVKAVWSSGDRTEAVCAATFLIGPQWKRFDGMLAVTALKGRKLLLFGVQPDGSVHQVEIPPELDDTHGRLRAARQGPDGALYITTSNGTDDKVLRITAS
>NZ_CP040605.1|WP_168586517.1|3303665_3307256_+|transcription-repair-coupling-factor
MSQAGPLRGLLEIVLRDPAIRRVVAAAGRPRLVLEGPPAARSLTAGSLAAEGGGGRPVLLVTATGREAEEAAAALSDLLGPARIEVFPSWETLPHERLSPRADTVGRRLSVLRRLAHPEEHAHGAIQVLVTTVRSLIQPIAPGLGELAPVRLAVGIEHDFQELVERLAELAYDRVDMVEKRGEFAVRGGIVDVFPPTEEHPLRVEFWGDEVTEIRPFAVADQRSLPDAPSTELFAPACRELLITEQVAERAAKLAEQHQTDTHLAEMLEKIASGAPVEGMEALIPALCEGEMRLLTDLVPAGTHVLLADPEKIHARAADLVRTGQEFLEASWMVAADGGKAPIDLGASAYRRLAEVAEHTVSIGLPWWPLTQLTSEEGEDDEVIRLVLKPVDAYHGEIERAFADLRAHTAAGGAAVLVVAGAGTAQRAVQQLREAELPARLAEDGLAAEPESGVVTVVRGGLEDGFAAPEVALVVLTEADLTGGRGGTSTKDMRRMPSRRRNAVDPLALKTGDFVVHEQHGIGKYVEMVQRTVGGATREYLVLEYAASKRGQPGDRLFVPTDQLDEVTRYVGGEVPTLNKLGGSDWKNTKAKARKAVKEIAAELVQLYAARQSSPGHAFGADTPWQRELEDAFPYTETGDQMAAIDEVKADMQRPVPMDRVICGDVGYGKTEIAVRAAFKAVQDGKQVAVLVPTTLLAQQHLNTFTDRMRSFPVTVKGLSRFTDQMESEETIQGLADGSVDIVIGTHRLLQTGIRYKDLGLVIVDEEQRFGVEHKEHIKALRTHVDVLTMSATPIPRTLEMSMAGIREMSTILTPPEERHPILTYVGAYDQKQVAAAIRRELLRDGQVFFVHNRVHDIEKVARQLRELVPEARIVTAHGQMNEDRLEKIIQGFWEREHDVLVCTTIVETGLDISNANTLIVDRSDLLGLAQLHQLRGRVGRARERGYAYFLYPPEKPLTDMAHDRLATIAQNSELGAGMAVAMKDLEIRGAGNILGAEQSGHIAGVGFDLYVRLVGEAVDAFRRHAGAEPGETEEELTEVRVDLPIDAHIPHDYVPGERLRLEAYRKLAAAVDVEALDAVRAELVDRYGPLPEPVERLLKVARFRQVCREHGVREATLQGASLRVAPLELPDSKQVRLKRLYPKALYKPAVRTVSVPRPTEGAAGGRMGAPPLRDEALLDWCAKFLEDLTTAPVKP
>NZ_CP040605.1|WP_168586518.1|3307395_3309087_+|BCCT-family-transporter
MNRKASEPEKAGIPQSPAAFAAEHSARTDFVIFGVTAAITIFFVCWGVFSTDSLARVSSAALSWLVTNIGWGFVLAATGFVVFALWLAISRYGAIPLGQDGEQPEFRTVSWIAMMFSAGMGIGLMFFGVAEPLAHFAEPPPGTVEPLSEAAVETAMATSLFHWTLHPWSIYAVVGLSIAYCSFRRGRKQLISAVFTPLIGKRGAEGPIGKLIDILALFATLFGSAASLGLGTLQIQSGMQSAGWINGAGNTVLVLIILVLTICFIFSAVSGVAKGIQWMSNINMVLAALLAIFVFVVGPTVFVLNLLPTSIGAYLRDFGEMASRSGATGGAAMNDWLSSWTIFYWAWWISWTPFVGMFIARISRGRTIRQFVAGVILVPSAVSLVWFAIFGGSSIRVQQSGVDVFRSGGEEAQTFRVLETLPLSVITTVLVMVLVAIFFVSGADAASVVMGTLSQRGSIEPKRWMVVFWGAATGAVAAIMLIIGGENALSGIQNLTFLASAPFAVVMVLLCVALMKDLREDPLMQRGEKGAQVLERAVIAGTDRHGGDFQLEVGPTAGDLKPY
>NZ_CP040605.1|WP_168586519.1|3309268_3309814_+|hypothetical-protein
MSMRTKLILATSSIALSALALTGCATGGPAPAPAPSAGGAVQSGAASNLTSSAAEPEIRAGVHGSEERVVFDFSKLPNASGLKVMKHELNETAPVWGGSGEPVEGMTGKVLLHVYVEIADQDRSTAGPEQFGQELAQSAVVNDNSHGTGELTIGLSEGVDYEVLVEGEKVIVNMAQGSLGR
>NZ_CP040605.1|WP_168586520.1|3309906_3310854_+|hypothetical-protein
MPRHGRLLASIAAAGLLLAGCGSGPSQVGAAAIVGDNRIPVSDVQSWFGEVLAKEPGLREKWQQQGQLDDLGRKLASQLVLQELVAQAARDEGLTVTDQQVADLINQVGGPQTATEGGINTPEGLRDVVRTYLLETELGRKYVDRLAITFDYSRASTRGEAEEKAKRMAQGPAEAAALVQEDAKAGVLAVLDQKLRPSDDPKLAPLFGAQPGTVLAFEPETNSGQWLIARIKERRTDAPPTASSGGMGDQMLQSLGIGLLGITADRVGVRLSPRYGVWDRVNLVAVPSEGETAGFRLSAPAPAPAPAPVPAPAAG
>NZ_CP040605.1|WP_168586521.1|3310992_3312009_+|MazG-family-protein
MSEVRVQEGSAVVVVDDRLGDVLPAAALPLLRSAAAVYAEPGLAPATRAALDAPAPPAAADLLAQAAREPVVLIVGALGCADADALRAAGARLIAAPAPAGIELLDAVTVMDRLRSPGGCPWDAEQDHDTLRKYLVEETYELLDAIEHRDREALREELGDVLLQVLFHARVATEDPADPFDIDAVAAGLVSKLVSRHPHVFADGPALLDAESQHARWEELKQQEKQRESIVDGVALGQPAVALAAKLVQRANRAGIPADAMPRGETPGEVLFDSAAQAKLAGHDPEDQLRAVALAFAERIRSAERRARESGREPAELSAADWRELVSDLPDPAGVRSE
>NZ_CP040605.1|WP_168586522.1|3312133_3312913_+|murein-transglycosylase
MPRRLWLLLAPVLTLLASCAPPVSSSRGSTEFTPPSAVAPPDPGVAPPMVELLAPGGPPIPPSARPQRQLAGWAESMADELNIPRAALQAYGYAQQAIEAKSPTCGLSWSLLAGIGAVESSHGRFGGARLDETGRPSKPIIGLPLDGSSGVKRIPDTDDGEFDGDTVWDRAVGPLQFIPSTWRAWAIDADGDGVRDPQDIDDAALAAGNYLCSVGGDLNDPERFWAALLAYNKSRSYGQEVLDYADYYGKASRALGVEG
>NZ_CP040605.1|WP_168586523.1|3313402_3313780_-|tetratricopeptide-repeat-protein
MTTEGTVEAFRRAEELLAQRRPLEAIRVLEPVLDIAADKPSVQLLLGRAYFFSAQLRRAERAFLRVLEFDPSDHYARLVLGRTLQRLGRLNEARAQIRLAATMHPVPAYQEALGEINAHIATRDI
>NZ_CP040605.1|WP_168586524.1|3314055_3315342_+|phosphopyruvate-hydratase
MAIIEQVGAREILDSRGNPTVEVEVALEDGTLSRAAVPSGASTGEHEAVELRDGDAARYGGKGVENAVAAVLDEIGPELTGLDATEQRVVDQKLVDLDGTPDKSRLGANAILGVSLAVAKAAAETSGLELFRYVGGPNAHVLPVPMMNILNGGAHADTGVDIQEFMIAPIGADTFSEALRWGTETYHALKTVLKAKGLATGLGDEGGFAPDLPNNREALDLIASAVEKAGYKLGRDIVLALDVAATEFFSEGAYNFEGSKRTADQMAAYYQELLGAYPLVSIEDPLAEDDWDGWTSLTEQVGDQVQLVGDDLFVTNPERLEDGISRGAANALLVKVNQIGTLSETLDAVSLATSCGYKSMMSHRSGETEDTTIADLAVATGCGQIKTGAPARSERVAKYNQLLRIEEGLGDAARYAGELAFPRFTPES
>NZ_CP040605.1|WP_168586525.1|3315345_3315882_+|septum-formation-initiator-family-protein
MPVGRASDPQRRNRRGESPAERRGERVRRDGTRTSGRRPGRQASTRSRPRSSTGGAFKLSSTRRAAGLAMLVCVMALSVSVPLRTYLSQRAELAQQEQQQAELTQQVRELEQRKAELSDPAQVEAEARARLGYVRPGETPYIVEVPTEPAAPPPPVAPAEDGAPWYEDLWNSVMGKGS

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Crispr_ID: NZ_CP040605_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_13

3319166-3319296

Unclear

Consensus_repeat	Method
CAGCCTGCGCCACCGCAGAGCTC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP040605_13

>merge|NZ_CP040605|13|3319166-3319296|CRISPRCasFinder
CAGCCTGCGCCGCCGTCGAGTTCGGGCCAACCGGGCCTGCCACCAAGCTTGGGCCAGCCTGCGCCACCGCAGAGCTCAAGCCAACCAGGTCCACCGCCGATTTCGGATCAGCCTGCGCCACCGCAGAACTC

>NZ_CP040605|13|12|3319166-3319296|CRISPRCasFinder
CAGCCTGCGCCGCCGTCGAGTTC	GGGCCAACCGGGCCTGCCACCAAGCTTGGGC
CAGCCTGCGCCACCGCAGAGCTC	AAGCCAACCAGGTCCACCGCCGATTTCGGAT
CAGCCTGCGCCACCGCAGAACTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168586521.1\|3310992_3312009_+\|MazG-family-protein	unknown	unknown	gnl\|CDD\|237065
NZ_CP040605.1\|WP_168590090.1\|3315884_3316385_+\|DUF501-domain-containing-protein	unknown	unknown	gnl\|CDD\|224424
NZ_CP040605.1\|WP_168584099.1\|3317509_3317815_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|173843
NZ_CP040605.1\|WP_168590092.1\|3324756_3325758_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223521
NZ_CP040605.1\|WP_168586529.1\|3323776_3324736_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224094
NZ_CP040605.1\|WP_168584616.1\|3316527_3317364_-\|transposase-family-protein	unknown	unknown	gnl\|CDD\|372577
NZ_CP040605.1\|WP_168586520.1\|3309906_3310854_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372652
NZ_CP040605.1\|WP_168586523.1\|3313402_3313780_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NZ_CP040605.1\|WP_168590091.1\|3321167_3322784_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173853
NZ_CP040605.1\|WP_168586534.1\|3328817_3329390_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NZ_CP040605.1\|WP_168586532.1\|3327100_3327982_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238045
NZ_CP040605.1\|WP_168586524.1\|3314055_3315342_+\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP040605.1\|WP_168586528.1\|3322857_3323784_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223674
NZ_CP040605.1\|WP_168586527.1\|3319992_3320946_+\|Ppx/GppA-family-phosphatase	unknown	unknown	gnl\|CDD\|223326
NZ_CP040605.1\|WP_168586533.1\|3328415_3328634_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586525.1\|3315345_3315882_+\|septum-formation-initiator-family-protein	unknown	unknown	gnl\|CDD\|368217
NZ_CP040605.1\|WP_168586519.1\|3309268_3309814_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586531.1\|3326835_3327084_-\|DUF397-domain-containing-protein	unknown	unknown	gnl\|CDD\|377231
NZ_CP040605.1\|WP_168586530.1\|3325750_3326752_+\|dipeptide-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|236898
NZ_CP040605.1\|WP_168586522.1\|3312133_3312913_+\|murein-transglycosylase	unknown	unknown	gnl\|CDD\|225501

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168586521.1\|3310992_3312009_+\|MazG-family-protein	gnl\|CDD\|237065	PRK12334, PRK12334, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	1.71895e-76
NZ_CP040605.1\|WP_168590090.1\|3315884_3316385_+\|DUF501-domain-containing-protein	gnl\|CDD\|224424	COG1507, COG1507, Uncharacterized conserved protein [Function unknown].	1.29453e-64
NZ_CP040605.1\|WP_168584099.1\|3317509_3317815_-\|hypothetical-protein	gnl\|CDD\|173843	cd01154, AidB, Proteins involved in DNA damage response, similar to the AidB gene product. AidB is one of several genes involved in the SOS adaptive response to DNA alkylation damage, whose expression is activated by the Ada protein. Its function has not been entirely elucidated; however, it is similar in sequence and function to acyl-CoA dehydrogenases. It has been proposed that aidB directly destroys DNA alkylating agents such as nitrosoguanidines (nitrosated amides) or their reaction intermediates.	5.09344e-18
NZ_CP040605.1\|WP_168590092.1\|3324756_3325758_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.98505e-176
NZ_CP040605.1\|WP_168586529.1\|3323776_3324736_+\|ABC-transporter-permease	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.45199e-87
NZ_CP040605.1\|WP_168584616.1\|3316527_3317364_-\|transposase-family-protein	gnl\|CDD\|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.95997e-24
NZ_CP040605.1\|WP_168586520.1\|3309906_3310854_+\|hypothetical-protein	gnl\|CDD\|372652	pfam13624, SurA_N_3, SurA N-terminal domain. This domain is found at the N-terminus of the chaperone SurA. It is a helical domain of unknown function. The C-terminus of the SurA protein folds back and forms part of this domain also but is not included in the current alignment.	8.62518e-07
NZ_CP040605.1\|WP_168586523.1\|3313402_3313780_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	2.48876e-10
NZ_CP040605.1\|WP_168590091.1\|3321167_3322784_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173853	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding domain of nickel/dipeptide/oligopeptide transport systems, which function in the import of nickel and peptides, and other closely related proteins. The oligopeptide-binding protein OppA is a periplasmic component of an ATP-binding cassette (ABC) transport system OppABCDEF consisting of five subunits: two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Similar to the ABC-type dipeptide and oligopeptide import systems, nickel transporter is comprised of five subunits NikABCDE: the two pore-forming integral inner membrane proteins NikB and NikC; the two inner membrane-associated proteins with ATPase activity NikD and NikE; and the periplasmic nickel binding NikA, which is the initial nickel receptor that controls the chemotactic response away from nickel. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand binding domains of ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	8.50282e-126
NZ_CP040605.1\|WP_168586534.1\|3328817_3329390_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	4.67913e-13
NZ_CP040605.1\|WP_168586532.1\|3327100_3327982_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	6.49831e-08
NZ_CP040605.1\|WP_168586524.1\|3314055_3315342_+\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP040605.1\|WP_168586528.1\|3322857_3323784_+\|ABC-transporter-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.0032e-90
NZ_CP040605.1\|WP_168586527.1\|3319992_3320946_+\|Ppx/GppA-family-phosphatase	gnl\|CDD\|223326	COG0248, GppA, Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism].	1.91753e-102
NZ_CP040605.1\|WP_168586525.1\|3315345_3315882_+\|septum-formation-initiator-family-protein	gnl\|CDD\|368217	pfam04977, DivIC, Septum formation initiator. DivIC from B. subtilis is necessary for both vegetative and sporulation septum formation. These proteins are mainly composed of an amino terminal coiled-coil.	1.83857e-14
NZ_CP040605.1\|WP_168586531.1\|3326835_3327084_-\|DUF397-domain-containing-protein	gnl\|CDD\|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.32471e-20
NZ_CP040605.1\|WP_168586530.1\|3325750_3326752_+\|dipeptide-ABC-transporter-ATP-binding-protein	gnl\|CDD\|236898	PRK11308, dppF, dipeptide transporter ATP-binding subunit; Provisional.	4.22142e-162
NZ_CP040605.1\|WP_168586522.1\|3312133_3312913_+\|murein-transglycosylase	gnl\|CDD\|225501	COG2951, MltB, Membrane-bound lytic murein transglycosylase B [Cell envelope biogenesis, outer membrane].	1.61066e-28

>NZ_CP040605.1|WP_168584099.1|3317509_3317815_-|hypothetical-protein
MALIDAPPSFSTHPGSRKPPPLARFDPLATATGSMKAPTVVAEALECLGGNGYVEESGMMLYREAPLSSIREGSGNVTALDLLRALDPPTQFPLKSKAQFQ
>NZ_CP040605.1|WP_168584616.1|3316527_3317364_-|transposase-family-protein
MVTYSAKLDVPRELVVFLSRLLAGERRRKGTRKGRRALTTFWQAVLVLRWFRDDTDITKLARDHGVARATGYRYVDEGIKALAAQAPDLHDALQRAKDNGDAYLILDGKNFSSDRLGEKTTSAKGAEIDLWYSGKTREQAGNIQALTDPDGFPLWASDVEPGSIHDITAAENHVLGALYWAYSQLNLPTLADGGYQGAGAGVLTPIKRPKTSKGRPLDVDNQTYNKLLRGLRALGERGFALLTGRWRVLRHFTTSPRKIGLIVKAALVLTQFEHGRLA
>NZ_CP040605.1|WP_168590090.1|3315884_3316385_+|DUF501-domain-containing-protein
MNLGVPTVSDADRECIRRQLGRPPRGLHAIAARDAAGEPTVVQTWPRLEDGTPFPTLYYLTAPQLVAHASTFEAEGLMREMAERLTTDPDLAERYRHAHESYLAERDALESLGTQVSAGGMPDRVKCLHVHIAHALAKGPGVNPFGDEAIDLIAERWPEHRYLLNR
>NZ_CP040605.1|WP_168586525.1|3315345_3315882_+|septum-formation-initiator-family-protein
MPVGRASDPQRRNRRGESPAERRGERVRRDGTRTSGRRPGRQASTRSRPRSSTGGAFKLSSTRRAAGLAMLVCVMALSVSVPLRTYLSQRAELAQQEQQQAELTQQVRELEQRKAELSDPAQVEAEARARLGYVRPGETPYIVEVPTEPAAPPPPVAPAEDGAPWYEDLWNSVMGKGS
>NZ_CP040605.1|WP_168586524.1|3314055_3315342_+|phosphopyruvate-hydratase
MAIIEQVGAREILDSRGNPTVEVEVALEDGTLSRAAVPSGASTGEHEAVELRDGDAARYGGKGVENAVAAVLDEIGPELTGLDATEQRVVDQKLVDLDGTPDKSRLGANAILGVSLAVAKAAAETSGLELFRYVGGPNAHVLPVPMMNILNGGAHADTGVDIQEFMIAPIGADTFSEALRWGTETYHALKTVLKAKGLATGLGDEGGFAPDLPNNREALDLIASAVEKAGYKLGRDIVLALDVAATEFFSEGAYNFEGSKRTADQMAAYYQELLGAYPLVSIEDPLAEDDWDGWTSLTEQVGDQVQLVGDDLFVTNPERLEDGISRGAANALLVKVNQIGTLSETLDAVSLATSCGYKSMMSHRSGETEDTTIADLAVATGCGQIKTGAPARSERVAKYNQLLRIEEGLGDAARYAGELAFPRFTPES
>NZ_CP040605.1|WP_168586523.1|3313402_3313780_-|tetratricopeptide-repeat-protein
MTTEGTVEAFRRAEELLAQRRPLEAIRVLEPVLDIAADKPSVQLLLGRAYFFSAQLRRAERAFLRVLEFDPSDHYARLVLGRTLQRLGRLNEARAQIRLAATMHPVPAYQEALGEINAHIATRDI
>NZ_CP040605.1|WP_168586522.1|3312133_3312913_+|murein-transglycosylase
MPRRLWLLLAPVLTLLASCAPPVSSSRGSTEFTPPSAVAPPDPGVAPPMVELLAPGGPPIPPSARPQRQLAGWAESMADELNIPRAALQAYGYAQQAIEAKSPTCGLSWSLLAGIGAVESSHGRFGGARLDETGRPSKPIIGLPLDGSSGVKRIPDTDDGEFDGDTVWDRAVGPLQFIPSTWRAWAIDADGDGVRDPQDIDDAALAAGNYLCSVGGDLNDPERFWAALLAYNKSRSYGQEVLDYADYYGKASRALGVEG
>NZ_CP040605.1|WP_168586521.1|3310992_3312009_+|MazG-family-protein
MSEVRVQEGSAVVVVDDRLGDVLPAAALPLLRSAAAVYAEPGLAPATRAALDAPAPPAAADLLAQAAREPVVLIVGALGCADADALRAAGARLIAAPAPAGIELLDAVTVMDRLRSPGGCPWDAEQDHDTLRKYLVEETYELLDAIEHRDREALREELGDVLLQVLFHARVATEDPADPFDIDAVAAGLVSKLVSRHPHVFADGPALLDAESQHARWEELKQQEKQRESIVDGVALGQPAVALAAKLVQRANRAGIPADAMPRGETPGEVLFDSAAQAKLAGHDPEDQLRAVALAFAERIRSAERRARESGREPAELSAADWRELVSDLPDPAGVRSE
>NZ_CP040605.1|WP_168586520.1|3309906_3310854_+|hypothetical-protein
MPRHGRLLASIAAAGLLLAGCGSGPSQVGAAAIVGDNRIPVSDVQSWFGEVLAKEPGLREKWQQQGQLDDLGRKLASQLVLQELVAQAARDEGLTVTDQQVADLINQVGGPQTATEGGINTPEGLRDVVRTYLLETELGRKYVDRLAITFDYSRASTRGEAEEKAKRMAQGPAEAAALVQEDAKAGVLAVLDQKLRPSDDPKLAPLFGAQPGTVLAFEPETNSGQWLIARIKERRTDAPPTASSGGMGDQMLQSLGIGLLGITADRVGVRLSPRYGVWDRVNLVAVPSEGETAGFRLSAPAPAPAPAPVPAPAAG
>NZ_CP040605.1|WP_168586519.1|3309268_3309814_+|hypothetical-protein
MSMRTKLILATSSIALSALALTGCATGGPAPAPAPSAGGAVQSGAASNLTSSAAEPEIRAGVHGSEERVVFDFSKLPNASGLKVMKHELNETAPVWGGSGEPVEGMTGKVLLHVYVEIADQDRSTAGPEQFGQELAQSAVVNDNSHGTGELTIGLSEGVDYEVLVEGEKVIVNMAQGSLGR
>NZ_CP040605.1|WP_168586527.1|3319992_3320946_+|Ppx/GppA-family-phosphatase
MSRVAAIDCGTNSIRLLVADVTAHDDGRRDLRDVYRGMRIVRLGQGVDATGRLADEALERTQAALAEYAAIAVRKGVERVRMVATSATRDASNREDFFAMVRETLGVDAEVITGDEEARLSFTGAVGDLDPEDGPFVVTDIGGGSTELVVGTWDGVRADITAAYSADVGCVRLTERCLHSDPPTDEEVREAEKVARQILDDAFAAVDCSGARTWVGVAGTVTTLSAIAQRLPEYDPAAIHLSHISQIRVEQISDDLFRMTHDERAAIGAMHPGRVDVIGGGALVVKVLADELAERAGISVMTVSEHDILDGIALSIS
>NZ_CP040605.1|WP_168590091.1|3321167_3322784_+|ABC-transporter-substrate-binding-protein
MAAMVAAPLAVAMIATGCGGGGSGSGDDGIVTLDWGEPENPLVPANTTEENGGFVVNALFTGLVDYRASDLKVENAVADSIESTDHQNYTIKLKPGWTFHDGTPVKAKNFVDAWNYNAYGPNGLQGASFFEQIDGYDQMQSEDPDGKDGPQQAPPPAAKELSGLKVVDDNTFTVRLKAPFTIFPVVLGYSAYMPLPDSFFKDPKAFEEHPIGNGPFKFESRVPNQELNVTAYENYAGANKPAIKGAKFKVYEQLDSAYQDLTAGNLDFLRAIPVSALIGDKWKQDLGEHAHQKPGLLTQTLGFPLYDPKFKNPLLRKAISMSIDRKTITQQVFAGGRDPADGFATAAVDGYHPNQCGEACEFNPEKAKQYLQQAGGFQGVLTVETNGDGGHNEWVQAVAASIKQNLGIETQFVPTPTFGEFRQKANGYKFSGLFRTGWKADYPNIETFLTQLYRTNASSNDYKYSNPAFDAALDKANAAPTIEAATAAYADAEKLLADDLPLIPLWTQPVQYGFSERIAEGEVKAYRELDLTTVRLKQ
>NZ_CP040605.1|WP_168586528.1|3322857_3323784_+|ABC-transporter-permease
MGRYLLRRLLQLIPVFIGTTLIIYLLVWAIPGDPFAGKCGDRGCPPAYIAEMHEKYNLDDPLIVQYFKYLGKLLTGDFGETYAGIQISTLIQNAYPTTIKLAVVALVIEGVIGLAAGILTGLRGRGFLDNLVLVSTLFLISLPVFVTGFVLQITLGSELGIIKPTVSANPSIGELIVPGFVLGSLSMAYVARLTRTAMMENRHADFVRTAVAKGLEPKRVVGVHLLRNSLIPVITFLGTDLGTLMGGAIVTEGVFNIHGIGGLVFKSILTKEGATVTGIVTLLVLVYLLMNLLVDILYAVLDPRIRYD
>NZ_CP040605.1|WP_168586529.1|3323776_3324736_+|ABC-transporter-permease
MTDQSVSSLVTGPAVGPEDPVPSTTGGKSQKPRGLWGDAWLELRRRPLFIAASLIILALLFITAFPGVFTSVDPSWTNLSKSRQPPSAEAWFGYDNLGRDIFARAIYGTRASIAVGVLATLLTVLFGGAVGIIAGFFGGWVDNLLSRFSEIFLGLPFVLGAIVILTTFNAEVAIPSATRIVAQVVLTIAVLSWPISMRIMRSAAISAKQQDYVKAARALGASAPRIILRHMLPNCLAPVLVYSTIALGGFIGAEATLSFLGIGLRDPVVSWGVMIAESRFYIQAAPHLLFFPAGFLVITVLAFVMLGDAVRDALDPKQR
>NZ_CP040605.1|WP_168590092.1|3324756_3325758_+|ABC-transporter-ATP-binding-protein
MDNKAPAERLLEVEDLHVEFRTRDGVAKVLNGVSYHVDAGETLAVLGESGSGKSVTAQTIMGILDIPPGAITGGAIRYQGEDLLTASDSRRRELRGDSMAMIFQDALSALNPVYTVGFQIAEQLRMRRGMSRKAAMARTVELLDQVKIPNAKQRVKEYPHQFSGGMRQRAMIAMSLALDPELLIADEPTTALDVTVQAQIMDLLDELRRELGMGLILITHDLGVVAEVADRIVVMYAGRIVESADAYSLYKQPGHPYTEGLMRSIPRLDLKGQELETIKGLPPNLLAVPPGCPFHPRCPRAQERCRQEVPTYHQLGLGRASACHFAEELMTRG
>NZ_CP040605.1|WP_168586530.1|3325750_3326752_+|dipeptide-ABC-transporter-ATP-binding-protein
MAEPILQVRDLVKHFPVTQGVLFKRTIGHVRAVDGVSFDLNRGETLGVVGESGCGKSTLAQVLMRLEKPTSGTALFEGRDMFKMRGAELRKLRRDLQIVLQDPYTSLNPRRTVGDIIGEPFEIHPEVAPKGERRRKVQELLEVVGLNPEHIQRYPHQFSGGQRQRIGIARALALRPKVIICDEPVSALDVSIQAQVMNLLGDLQHEFGLSYVFIAHDLGVVRHLSDRVAVMYLGKIVEIGSDEQIYEHPQHPYTQALLSSVPVPDPTLRGKREIIRLTGDVPSPANPPSGCRFRTRCWKAQDICAEKVPELEVRLGDHPSACHFAEERPRVIS
>NZ_CP040605.1|WP_168586531.1|3326835_3327084_-|DUF397-domain-containing-protein
MQRDEAILWRKSSYSQGQGTCVEVGWRKSSYSPHNDNCVEVGVGFDAVGIRDTKDRDGGHLAVTPARWQAFLRAVKDGALDA
>NZ_CP040605.1|WP_168586532.1|3327100_3327982_-|helix-turn-helix-domain-containing-protein
MLYGMPTPTVRRLLVGHLLRHAREQTGLDLDAAGKLIGKTNSTMSRIERGHTALPQHVLKKLANAYEQHAPNAIDLDELLDLARGSQDRGRWSGYRSVYSKYFRMAVDLEADAAAIFQYQTEIVPGLLQTEQYIRALFTTSQVQPSDQSTEDAVEARLERQSVLTKPKAPQVSFVLSESSLRRLVGDRELMENQLRHTAEIARLRNVQIQVLPFDAATAPRATHDFKLFRVPSPGNAGPLEFLYVEDFTDGRYLDRHDDVHAYTLLWQQLVAAALDPVESEKFILRVADEFAR
>NZ_CP040605.1|WP_168586533.1|3328415_3328634_+|hypothetical-protein
MFWLQVSTLVLVNVLIASMLLVRLPRAQHGGAGEGALNVWQLIEDIEAERQREAVATGRHHLDTETLARLRI
>NZ_CP040605.1|WP_168586534.1|3328817_3329390_-|TetR/AcrR-family-transcriptional-regulator
MTTKNASGKRLRADAQRNRERVLAAAQELFAAEGLAVPLDDIARRAGVGPGTVYRHFPTKEALFEAVVVERIQRMVEEARDHATADDPGRAFYDYFQRVIEHAALNKDICDALESTGQQPRTACPENDFNNAIGTLLERAQQAGAVRADVTTAELRSLIVGALTMYRRAVAEQRPAHELAVLYAGLRPAR

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Crispr_ID: NZ_CP040605_14

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_14

3393026-3393105

Orphan

Consensus_repeat	Method
ACCGGCCGGGCACACCACCACCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040605_14

>merge|NZ_CP040605|14|3393026-3393105|CRISPRCasFinder
ACCGGCCGGGCACACCACCACCGGCATATCCCGGTGGGGTACCGGGTGTTGGTCCGGACCGGCCGGGCACACCGCCACCG

>NZ_CP040605|14|13|3393026-3393105|CRISPRCasFinder
ACCGGCCGGGCACACCACCACCG	GCATATCCCGGTGGGGTACCGGGTGTTGGTCCGG
ACCGGCCGGGCACACCGCCACCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168586589.1\|3383441_3385028_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586591.1\|3386143_3387241_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586592.1\|3387228_3388335_-\|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl\|CDD\|379325
NZ_CP040605.1\|WP_168590101.1\|3403938_3404439_+\|phenazine-biosynthesis-protein	unknown	unknown	gnl\|CDD\|367435
NZ_CP040605.1\|WP_168586598.1\|3404455_3405298_-\|PhzF-family-phenazine-biosynthesis-protein	unknown	unknown	gnl\|CDD\|223461
NZ_CP040605.1\|WP_168586603.1\|3412472_3414788_+\|polyprenyl-synthetase	unknown	unknown	gnl\|CDD\|223220
NZ_CP040605.1\|WP_168590100.1\|3385236_3385887_-\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|238741
NZ_CP040605.1\|WP_168586594.1\|3389705_3390014_+\|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|376829
NZ_CP040605.1\|WP_168586600.1\|3406950_3408927_-\|phenazine-specific-anthranilate-synthase-component-I	unknown	unknown	gnl\|CDD\|223225
NZ_CP040605.1\|WP_168586599.1\|3405342_3406905_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|236111
NZ_CP040605.1\|WP_168586593.1\|3389468_3389669_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168590099.1\|3381551_3381908_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586595.1\|3390020_3390323_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586601.1\|3409978_3411487_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|197715
NZ_CP040605.1\|WP_168586604.1\|3414791_3415409_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP040605.1\|WP_168590102.1\|3409378_3410005_+\|isochorismatase-family-protein	unknown	unknown	gnl\|CDD\|238495
NZ_CP040605.1\|WP_168586590.1\|3385024_3385231_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586597.1\|3402726_3403254_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235401
NZ_CP040605.1\|WP_168586602.1\|3412052_3412304_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|187721
NZ_CP040605.1\|WP_168586588.1\|3383078_3383438_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168586598.1\|3404455_3405298_-\|PhzF-family-phenazine-biosynthesis-protein	gnl\|CDD\|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	1.06458e-83
NZ_CP040605.1\|WP_168586592.1\|3387228_3388335_-\|protein-phosphatase-2C-domain-containing-protein	gnl\|CDD\|379325	pfam13672, PP2C_2, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.	6.20137e-15
NZ_CP040605.1\|WP_168590101.1\|3403938_3404439_+\|phenazine-biosynthesis-protein	gnl\|CDD\|367435	pfam03284, PHZA_PHZB, Phenazine biosynthesis protein A/B.	3.90016e-84
NZ_CP040605.1\|WP_168586603.1\|3412472_3414788_+\|polyprenyl-synthetase	gnl\|CDD\|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	1.37422e-45
NZ_CP040605.1\|WP_168586597.1\|3402726_3403254_+\|hypothetical-protein	gnl\|CDD\|235401	PRK05306, infB, translation initiation factor IF-2; Validated.	0.00247461
NZ_CP040605.1\|WP_168586594.1\|3389705_3390014_+\|YbaB/EbfC-family-nucleoid-associated-protein	gnl\|CDD\|376829	pfam02575, YbaB_DNA_bd, YbaB/EbfC DNA-binding family. This is a family of DNA-binding proteins. Members of this family form homodimers which bind DNA via a tweezer-like structure. The conformation of the DNA is changed when bound to these proteins. In bacteria, these proteins may play a role in DNA replication-recovery following DNA damage.	3.17281e-08
NZ_CP040605.1\|WP_168586600.1\|3406950_3408927_-\|phenazine-specific-anthranilate-synthase-component-I	gnl\|CDD\|223225	COG0147, TrpE, Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism].	1.19941e-57
NZ_CP040605.1\|WP_168586599.1\|3405342_3406905_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|236111	PRK07843, PRK07843, 3-oxosteroid 1-dehydrogenase.	8.99114e-114
NZ_CP040605.1\|WP_168586601.1\|3409978_3411487_-\|hypothetical-protein	gnl\|CDD\|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	1.61508e-16
NZ_CP040605.1\|WP_168586604.1\|3414791_3415409_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	4.91258e-58
NZ_CP040605.1\|WP_168590102.1\|3409378_3410005_+\|isochorismatase-family-protein	gnl\|CDD\|238495	cd01013, isochorismatase, Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological systems. Isochorismatase is part of the phenazine biosynthesis pathway. Phenazines are antimicrobial compounds that provide the competitive advantage for certain bacteria.	1.43673e-103
NZ_CP040605.1\|WP_168590100.1\|3385236_3385887_-\|VWA-domain-containing-protein	gnl\|CDD\|238741	cd01464, vWA_subfamily, VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Members of this subgroup have no assigned function. This subfamily is typified by the presence of a conserved MIDAS motif.	3.46454e-18
NZ_CP040605.1\|WP_168586602.1\|3412052_3412304_+\|hypothetical-protein	gnl\|CDD\|187721	cd08653, FMT_core_like_3, Formyl transferase catalytic core domain found in a group of proteins with unknown functions. Formyl transferase catalytic core domain found in a group of proteins with unknown functions. Formyl transferase catalyzes the transfer of one-carbon groups, specifically the formyl- or hydroxymethyl- group. This domain contains a Rossmann fold and it is the catalytic domain of the enzyme.	0.00264426

>NZ_CP040605.1|WP_168586595.1|3390020_3390323_+|hypothetical-protein
MPKYASERIAEELVRAQDRYNQAVQQSQELGEKQVVVDLEDELGQLVLTAYGQVVDVRLRADELRNADGRHLAEVVMRRCNRSRLAASRLREPEESKGWL
>NZ_CP040605.1|WP_168586594.1|3389705_3390014_+|YbaB/EbfC-family-nucleoid-associated-protein
MSEIPDIEAMLAELDEKMNTVQALRDEAVASTYTGSSADQAVVARVDGLGAIQDLSIPDAELRSNHPSALGGKILEAINSARAQAVDDSNAKMIEALPGFGS
>NZ_CP040605.1|WP_168586593.1|3389468_3389669_+|hypothetical-protein
MGTAGAGQRGQSDEDQEHERKYIRNTDEHFGFSGEIDPNTGHAVAPPVIGDADADSDETPNEDDIA
>NZ_CP040605.1|WP_168586592.1|3387228_3388335_-|protein-phosphatase-2C-domain-containing-protein
MLVIVAALLELYFAPAQWLYRLVVDALALPGAIMGGLVLWGEPGEVPKSPEIVVRERIPPRPAAPVRERPPVRVEGVPVPPRFGRGSKAQALPWLLSAHTVYPGIAADEAQLGDLAVRAASVVGPGHRCEEPVVPRQDAYRLGRDDNGRYLIVAVADGVSSSRFAELGATVAVSAATNVLRDWLNAAPDLKNLAATEIFSGVAAQMADTATSRHLRDSDICAALVTAVIPACPAPGEREMWVAWVGDASVWTLRDGTWTFVAGDDKRTKEGMESNAVAHVLPDSPLAVTSRSIRLQNGTMVGLMTDGVGDALATLGEANGYFARKWANPPPSTSFVNDVSYDAERFIDDRTAVAIWVGADSREARWPR
>NZ_CP040605.1|WP_168586591.1|3386143_3387241_-|hypothetical-protein
MAEMTGTWPLPAVVTLDDLEPLKKTISAGAGQSTGIHPIEDRPGWLAKLYRTPGDHSEATRLDELIALPGGITADDSTTLGTSTSWPVARITKGDNPAHGCVIPAAPDRFRQDSAEGFREIDTLARTTDSFARQKLRVPSRSDRLRICRNLVLVAEVLERHKLVYSDWSYSNAFWCHDDASVFVIDIDGCGPGPVPNIVQPNWDDPLTQRPNKADACTDRFRVALLVTRCLTGQRDLAVALNDLAESDGLGNRGLREVLLDILLSEDRERRPSMAELGTVLAGGLYARFGSPPARSPIPARPPSVPSTSVVGGTPGKNVNWNTPATTSSAGNGEPGGPQRETVFIVAFFVIVVLLITIVLIANNV
>NZ_CP040605.1|WP_168590100.1|3385236_3385887_-|VWA-domain-containing-protein
MKQKCLPTYVVIDASYSMTPYQETLNQTLAQLHRKLAGSPRVSEFALMSIIAFSSSAQVVIEMTDMEKIPVMPDVVCNGQTDYRAAFDLVRQRIDVDVPALNAQGKAVLRPAMFFLTDGQPTEPGWEAAFRRLVDPAWNRHPHVITYGFGSVQSEVLSKVATKAAFYAEPGTRNDEALSQAINSLLNSLVASSRSEEMQIPTVAEGYRTIPVEYMD
>NZ_CP040605.1|WP_168586590.1|3385024_3385231_-|hypothetical-protein
MTSKRWDRSAVLLGAASLCVVAAAVASIAARVPGTEERPPVPGHEVRQHPPETPVDPRTSPNGPEVTR
>NZ_CP040605.1|WP_168586589.1|3383441_3385028_-|hypothetical-protein
MNCHHCGFDNEANFVLCAHCGRKRVIDLSGGAQTTITQPTPTATGLGTAPRVAPGTGFARDATRYLCAALQLDPGLNDKALQNILDEDYRAVASSPGVDLVTVLKYGLAARRRQLTRDVLIVLLGLIGLGVLASPQPGWALLVLFAGWAVMFIETLSTHYGILSAQLRRNAFDPANAPAPTRGRTAARLADIAARDRGNLTVFADYAPFAGYGITFGNWSFTLNVAKAEEGKDIVEFTVQELRDFVADSVRGIGLPGVLVEDRVFVSGLDLLHGFEPSVQQAILPNELAAPASRVDEAVLGRLHDDPNSRARPYLTVRVTGWSGELVVTMFLRFALSPQKDLLFVEANYSLLPPVKRRYQEVDRLLSSPTFRQLGRLAAMSLIRLVPAVFGGGQRVWAGLVSPLTRVLKSRREAREITQDRTFNYGATMSLREEAADNRYHRYFQQLDKEMYAKLAERRVMDALEEFLADHNVETSDLSERQTTILNNGIYVTGHGKLDAMSVAAGTNAIARTVTRAARTATPTKRQG
>NZ_CP040605.1|WP_168586588.1|3383078_3383438_-|hypothetical-protein
MRDNYGINISGSGSFNADAVAVGIGAQAVSAGGSQELRDLQEQVRELLAALRTARNGGEIDSDDVVADAEQLEEEINNDSPDKSRILGLLRKISSAVTQVGDLATAVQNAQDAVGSLLS
>NZ_CP040605.1|WP_168590099.1|3381551_3381908_-|hypothetical-protein
MSTTLSRDQCYSASSDYVPWSYTGSSGETATLCLDRVWVPRYCILAEKDDSDRMSIGTNTAVDCYATSIPSSYNTILVVSSVEENPSTSCSQSSSDPNTYWSMLADEGSSRVCFTYPT
>NZ_CP040605.1|WP_168586597.1|3402726_3403254_+|hypothetical-protein
MRVARLRESLKQAESDLASFEELLGWGAGLPAEVAGPPQRQRPGGPVAGTTRTREEAGEGSRAPKRPKVQGPAVEAGSGNHGGKGDGPAPTNPAAQQDPSAEKKPENRDSQAANREARKVEAARVEELKGKGEGQLNEKEKDELATLQRKVEQRKKKKQKNNANYRKLGKDVAAR
>NZ_CP040605.1|WP_168590101.1|3403938_3404439_+|phenazine-biosynthesis-protein
MTEAPQDAVAFGNEAELRRRNRATVEEYLRVTEGESRLQRHHLFTDDGTERGGLWTTDTGEPVFATGKDNLYSMAAWSLECFPDWKWINVEIYETQDPNRFWVECDGEGKILFPDYSPGHYKNHFIHSFLLENGKIKEIREFMNPCQQMRALGIEVPVIKRGGIPA
>NZ_CP040605.1|WP_168586598.1|3404455_3405298_-|PhzF-family-phenazine-biosynthesis-protein
MPNHAYVITDVFTATPLEGNPLAVFIDAASLSAEQMQRIAREMNLSETTFVLPAREVADARVRIFTPVNELPFAGHPTLGTAIVLGAELNQDTIRLETEVGVITFSFERANGKIVAARMLQPIPSWQPYEHADELLEGLGVAASELPVDAYRNGPRHVYVGLGSVAALEAIHPDLRVLAKFPDMAALCFAGAGTNWRLRMFSPAYGVAEDPATGSAAGPLAVHLARYGRIAFGSQITIRQGVEIGRPSTMYATVEGAGERIDQVEVVGAAVVVAHGTLVL
>NZ_CP040605.1|WP_168586599.1|3405342_3406905_-|FAD-dependent-oxidoreductase
MRPGVIVIGSGAAGLSAALAARAAGADVTVLEATSTLGGTTALSSGAVWVPNNHVEAAGRGRDCAEKAHRYLRSLAVGDVDPLLVNRFLDAGPRILRWLEGTSPLQWSPLPYPDCHSELPGGMEGGRSLEPCALQIEPILTHQLRPPLPWRLPAMLAELATGQVSLDVVNQRRRTGTVTGGQALVAALLIAARTAGVSFRTAARATRLVSDDGTVTGVDTRGQQLRGRVLLASGGFERDTGLVNAFLRMPVLRCVGAPGARGDGLRMAMSMGAALGNMSEAWWCPTTPDPDAEIDGEPLDRMLFAERARPGTLMVDRRGRRFINEAQNYNDVGRALHAFEPTEFCFERAPSWLIFDGIHRRDYTVGPVRRDASVPDWLPCGGTLAELADLIDVHAETLIQTVERFNAAAKDGLDPEFGRGTNAYDRAMGDPQATHPTLRPLTEPPFSALPVHAGLGGTKGGPRTDPHGRVLHVEGGVIRGLYAAGNVAASPFGFAYPGTGGTLGQALVFGALAGEAAAGD
>NZ_CP040605.1|WP_168586600.1|3406950_3408927_-|phenazine-specific-anthranilate-synthase-component-I
MAKRVVAGLKELLVSNPPPFAVLHRPEMGNRLEILLGEVTEVCSIEDLMIPPSSTGPARQELLVLVPYRQLTERGFECVDDGAPMLQMMVRSQGTVNVTEALGALPDEPVELKDARFDTDDETYAEVVRSVLRDEIGSGAGSNFVIRRSFTATLADFSPRDALSLFRRLLVAEQGTYWTFVVHTGSRTFVGASPEKHVSLDRGTVVMNPISGTYRYPPEGPSTQDVLRFLADRKEEDELHMVLDEELKMMARICDRGGTVVGPRLREMARLAHTEYLIEGQTKLDVRDILRETLFAPTVTGSPLESACRVIKRYEPSGRGYYSGAIALIGHDAAGYQTLDSAILIRTAEIERDGRLRAGVGATLVRHSDPGSEVAETRAKLAGMLAAFEGGVDAPHQRERGLSLDANPLVREALDGRNKSLARFWLRADRGHVPTVPGLVGRRVLVIDGEDTFTAMLGHQLTALGLTVSIRGYDESFEMDDDEFIVLGPGPGDPRVLDDPKIATLRRIARRLLHDRRRFLAVCLGHQVLCGLLGLEVVPEVVPNQGEQIDIDLLGERRTVAFYNTFVARSSSDRLYHRDLPGPVVISREPDSGRVHALSGPGFRSIQFHPESVLTIDGMSILGDLLGSLVPATESLPAQRGSSGVSGPARTGVRTSTG
>NZ_CP040605.1|WP_168590102.1|3409378_3410005_+|isochorismatase-family-protein
MPTADDVPRSSVDWTVSQYRAVLLIHDMQNYFLAKFPGDSPVLDLVRNIARLRECCADLGIPVAYTAQPGGMNSKQRGLLKDFWGPGMAANPADREIVAELAPAEHERVFTKWRYSAFHDSGLLDYLRDCGRDQLIVCGVYAHVGCLITSCDAFSHDIQPFLVCDAVADFSPEDHRMAVSYAAQRCAAVPTTDQVLAALTSTASVPTG
>NZ_CP040605.1|WP_168586601.1|3409978_3411487_-|hypothetical-protein
MRALLSKGWIESAVMLAEATLNDGVPEELAAELRCALIAPLITSGHTDEAIAIADQVLAVPDLSTTTFDDTAAGRMLALVLQGDFASDHASKVLQEPDGTCHGQARTAIALTGLAHLEWSAGNVAEALCWGRRAATCAASVKSADWRWYPPLMMAEMLGELGEFDDAEEMLRQARAEIDQFGLTMHAAQADLIRARLLLRAGRQTAARLTAEACLSSALELGTLRVVPSAESVLALIAFRSGDVALARSYLRRCRETSTYEQGSAARSARDEWIQLLVHTSKEDPSSIEALLHTNLLHRPALFVEEPGAAAWFVRVAMDVGDEKIAIKAIEAAHAVANANIGTPAVATGALHARSLFEPNLDGLLQVISEYGDAWARETAIKDLRALLGGGVLSSDRRDSRNVAESGRNDSTNAKNTDRPHGDAESIPPDLTKTERAIAELVGQGLTNRQIAHRIFLSPHTVNYHLRRIFRKLGINSRVELASRERYAVRREIRSSGRYGSS
>NZ_CP040605.1|WP_168586602.1|3412052_3412304_+|hypothetical-protein
MHTGDPRQRGLDVADWAVFGGRDAFGCALHLVDDCFGSPEESAGGGPFRFCRFELFFLYHDGQPVRGEDQERGAGNVRDVVAE
>NZ_CP040605.1|WP_168586603.1|3412472_3414788_+|polyprenyl-synthetase
MVRYLPGATIDPVVDDLPHLDCGMEWWYFHTHLTTEHGDDVGLFLVFTRHLATRAEGEPLRAHFAMIGRTDHTAGRHTSAVWVDRGWIDTVRTTITNDGVMDPGVRQALVELFDDGTPVAPDLLMGGEVMIAEQELDLRYGDVAALRKLADGSYHVTFDDETQSCDLVFTPVKPPIIQHDDAFQVRFQGPESQAFSYFAPRMAVQGRIGNATVSGSGWYEHTFGAEYLRPDGDQRYPDGTWNWTGIQLDNGWEISAATIDHIDVNSRQSVFAQRFATAYSPDCERVSCDVELVGDRPWTSLSSLNTYPTRWTLSAPALELDVVVEAELPQQEILTMVTHGSYLEACANVRGTMRGEPVSGRAFIEVMPANRVARIEEFLGRLRDVTHDEVRKLYPDSPSEALTMALAAREASGAPHAVVYDAMVRPLRYVSDTSGRGWRSFVTCAALELFGVRAEQYRQLLAVTELIHSGYLMVDDVEDDSPMRRGEPTAHLVFGAPTAINAGTASYFVLDRVLAEILPDERRRLRAYESYLRAMRGAHVGQGIDITGHHDAMNLAVASGDPTALLAGLRWAQRLKTGAYSRTLAEIGALTAGASDEQITAMGNYFEAVGLAYQITDDVMDLDGVTNRLPSGEVRATKHIGEDLRAGKVTMPLAQAVGRLPHDRMAAIWTAVRDGNADDVTVREVAAALVECGAVQACYDDAKAQVDAAWAPLDPLLPKSFAKAMVRALGFYASLREHEPAVGDHEAAAGERGTAAGHHEAAAGEYVNSGQ
>NZ_CP040605.1|WP_168586604.1|3414791_3415409_+|ABC-transporter-ATP-binding-protein
MVLRVNELYHRYGKRQVLRGVTFDVLPGSLVGVVGENGAGKTTLLRILCGELTPTTGTASVSGRLGYCPQHVVLNDAFTVAQHLAFFQVAYGLPDLSYAHELIDVLQFADFLDERVGVLSGGTRQKLNLTIALMHDPDVLLLDEPYQGFDWETYLRFWELAQRLRDRGRSVLVISHLAYDADRLDTLHRLAAGVLCEGTTSHGGR

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Crispr_ID: NZ_CP040605_15

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_15

3658903-3658992

Orphan

Consensus_repeat	Method
CCGGTAAGAACCGGCATTGTCACTCACGACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040605_15

>merge|NZ_CP040605|15|3658903-3658992|CRISPRCasFinder
CCGGTAAGAACCGGCATTGTCACTCACGACCGGACGGGCATCGGTCGTGAGTGGTTGTTCCGGTAAGAACCGGCATTGTCACTCACGACC

>NZ_CP040605|15|14|3658903-3658992|CRISPRCasFinder
CCGGTAAGAACCGGCATTGTCACTCACGACC	GGACGGGCATCGGTCGTGAGTGGTTGTT
CCGGTAAGAACCGGCATTGTCACTCACGACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168586775.1\|3657402_3658494_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|214891
NZ_CP040605.1\|WP_168586770.1\|3654166_3654481_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586784.1\|3664941_3665700_+\|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl\|CDD\|379325
NZ_CP040605.1\|WP_168586785.1\|3665689_3666181_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168584103.1\|3654681_3654924_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586768.1\|3653413_3653620_-\|DUF397-domain-containing-protein	unknown	unknown	gnl\|CDD\|377231
NZ_CP040605.1\|WP_168586771.1\|3654926_3655307_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379162
NZ_CP040605.1\|WP_168586772.1\|3655713_3655983_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586774.1\|3656885_3657152_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586776.1\|3658501_3658696_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586783.1\|3664479_3664935_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP040605.1\|WP_168586779.1\|3661155_3661581_+\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|223806
NZ_CP040605.1\|WP_168586777.1\|3659252_3659762_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586780.1\|3661615_3663079_+\|catalase	unknown	unknown	gnl\|CDD\|163712
NZ_CP040605.1\|WP_168590144.1\|3660073_3660469_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_CP040605.1\|WP_168586773.1\|3656304_3656775_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586781.1\|3663194_3663581_+\|ankyrin-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|222984
NZ_CP040605.1\|WP_168586778.1\|3660504_3660969_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319924
NZ_CP040605.1\|WP_168586769.1\|3653645_3653957_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586782.1\|3663899_3664334_+\|YbjN-domain-containing-protein	unknown	unknown	gnl\|CDD\|341119

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168586775.1\|3657402_3658494_+\|hypothetical-protein	gnl\|CDD\|214891	smart00894, Excalibur, Excalibur calcium-binding domain. Extracellular Ca2+-dependent nuclease YokF from Bacillus subtilis and several other surface-exposed proteins from diverse bacteria are encoded in the genomes in two paralogous forms that differ by a ~45 amino acid fragment, which comprises a novel conserved domain. Sequence analysis of this domain revealed a conserved DxDxDGxxCE motif, which is strikingly similar to the Ca2+-binding loop of the calmodulin-like EF-hand domains, suggesting an evolutionary relationship between them. Functions of many of the other proteins in which the novel domain, named Excalibur (extracellular calcium-binding region), is found, as well as a structural model of its conserved motif are consistent with the notion that the Excalibur domain binds calcium. This domain is but one more example of the diversity of structural contexts surrounding the EF-hand-like calcium-binding loop in bacteria. This loop is thus more widespread than hitherto recognised and the evolution of EF-hand-like domains is probably more complex than previously appreciated.	2.12586e-17
NZ_CP040605.1\|WP_168586784.1\|3664941_3665700_+\|protein-phosphatase-2C-domain-containing-protein	gnl\|CDD\|379325	pfam13672, PP2C_2, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.	0.00663098
NZ_CP040605.1\|WP_168586779.1\|3661155_3661581_+\|transcriptional-repressor	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	2.83903e-35
NZ_CP040605.1\|WP_168586781.1\|3663194_3663581_+\|ankyrin-repeat-domain-containing-protein	gnl\|CDD\|222984	PHA03100, PHA03100, ankyrin repeat protein; Provisional.	2.44834e-12
NZ_CP040605.1\|WP_168586780.1\|3661615_3663079_+\|catalase	gnl\|CDD\|163712	cd08156, catalase_clade_3, Clade 3 of the heme-binding enzyme catalase. Catalase is a ubiquitous enzyme found in both prokaryotes and eukaryotes, which is involved in the protection of cells from the toxic effects of peroxides. It catalyzes the conversion of hydrogen peroxide to water and molecular oxygen. Catalases also utilize hydrogen peroxide to oxidize various substrates such as alcohol or phenols. Clade 3 catalases are the most abundant subfamily and are found in all three kingdoms of life; they have a relatively small subunit size of 43 to 75 kDa, and bind a protoheme IX (heme b) group buried deep inside the structure. Clade 3 catalases also bind NADPH as a second redox-active cofactor. They form tetramers, and in eukaryotic cells, catalases are located in peroxisomes.	0
NZ_CP040605.1\|WP_168590144.1\|3660073_3660469_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	6.81974e-29
NZ_CP040605.1\|WP_168586768.1\|3653413_3653620_-\|DUF397-domain-containing-protein	gnl\|CDD\|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.81436e-12
NZ_CP040605.1\|WP_168586771.1\|3654926_3655307_+\|hypothetical-protein	gnl\|CDD\|379162	pfam13397, RbpA, RNA polymerase-binding protein. RbpA is a family bacterial RNA polymerase-binding proteins. RbpA acts as a transcription factor by binding to the sigma subunit of RNA polymerase.	4.4497e-22
NZ_CP040605.1\|WP_168586778.1\|3660504_3660969_+\|VOC-family-protein	gnl\|CDD\|319924	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	8.84529e-38
NZ_CP040605.1\|WP_168586783.1\|3664479_3664935_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.43288e-13
NZ_CP040605.1\|WP_168586782.1\|3663899_3664334_+\|YbjN-domain-containing-protein	gnl\|CDD\|341119	cd17036, T3SC_YbjN-like_1, T110839 is structurally similar to type III secretion system chaperones and YbjN family proteins. This family includes protein T110839 from Synechococcus elongatus that is structurally similar to type III secretion system (T3SS) chaperones (T3SC) that bind effector proteins, and is homologous to YbjN, a putative sensory transduction regulator protein found in Proteobacteria.	0.00873743

>NZ_CP040605.1|WP_168586776.1|3658501_3658696_-|hypothetical-protein
MLRGDTDSQIGSFDVGADVRVVLPPSEFHRRGIDTRMRQINLALEPGEDTEKTTGTLAGFPDVA
>NZ_CP040605.1|WP_168586775.1|3657402_3658494_+|hypothetical-protein
MIAGIIMLVGMAATVAMSIILWQQKAPGRSMWPWLVVGLLTMCLWPISLWVAIGLWWYWRGTPVLPAAGPYPQVVPGQAPPVRRGARGPLISVACVLGSLITIVVFSALVPPAPAQTNQATPARSTVPPSTSQPHPATSQTPRAQLPPEAVVLGVLDADRIRVQITGQAAQEIRIVGVDSPAAGADPECWGTEAKAFTEKTLLGQTVRVQLDAAWQPGTPDEQASAIFLSGGANYSRLALEQGFARLSVDAPAALIGELSQAETNARNAQVGLWGAPCFGATRLAPPPPPPAPEPQPEPQPEPQPEPEPEPEPSPDSDSRQSPVAYYPTCKAAKAAGAAPLYRGDPGYSSKLDRDGDGVACES
>NZ_CP040605.1|WP_168586774.1|3656885_3657152_-|hypothetical-protein
MCELVGVVVADGDAGSQDVVRRPWRDPVAGELAGEQGESGVAALAAVVQADRQSVDVLRSEAAHMPGSRGGAGCVPVPPPRSRAHATP
>NZ_CP040605.1|WP_168586773.1|3656304_3656775_+|hypothetical-protein
MQDLGAYFFQESKGIFAFLHYAMGAQNANLNALAAYDVARRPRIASRAAFGLLAECSRRDGETVEGYYRWVVSRKHDLGRYRGGSSGFDDEARSFAAAHFRSTGIPASPQEVLVCCGGAKGGIMAMLAAVMCRHENEKVHRMPGRVLAPAGYYVPG
>NZ_CP040605.1|WP_168586772.1|3655713_3655983_+|hypothetical-protein
MTAKKRKRDRFLPMAWRVERVAPDEVYTFRWGRGAGYFTVHRGDIGSSHGNERLVETVHIVRDWVDESDVAAQARSWLNTRAQSQRRPA
>NZ_CP040605.1|WP_168586771.1|3654926_3655307_+|hypothetical-protein
MEAYVPGRSVPRIPTSYQRPEDYEPVERFVERYVCPRGDEFAVVFAVDSVAPELWDCRRHGVVAVRADLSAGVMAVYGTCSGVERAQLGSPSRTHLEYVLERRSPGELQTLLDERLSELVAARERS
>NZ_CP040605.1|WP_168584103.1|3654681_3654924_+|hypothetical-protein
MSSLLMFLAGFMPGLVLLVLVGWRMHLAEPAGQHAGAGEGALTVAHLRDRVEREASGAESTGRHALREDVAARIAAIVGV
>NZ_CP040605.1|WP_168586770.1|3654166_3654481_+|hypothetical-protein
MLAGFRFVHPRKVDSLLAVQGFRIRDSAIDMFIAHSAFDAVAARVRVEEMRFEGPSPALWERRGAVADVVMELVALPPHGAPNAPKLARARSLDLLWVPGNAMS
>NZ_CP040605.1|WP_168586769.1|3653645_3653957_-|hypothetical-protein
MRCQLEHLAKLAEQPNIHLHVAPFRCRAVAALAYPFIRFRVPAANANTPALEFVFVEQLTNGDYLDSPNEVEEYSVLWSGLLGAALDPVESRELLLFIAAEFE
>NZ_CP040605.1|WP_168586768.1|3653413_3653620_-|DUF397-domain-containing-protein
MTPTRRFNGWHKAQASSGTGNGCVEVGYAPGYRGVRDSKLGEASPVMAFDHRNWSAFLTAVKAGELDG
>NZ_CP040605.1|WP_168586777.1|3659252_3659762_-|hypothetical-protein
MTETSSDEIATDSESGSEKLQDLLKEELSRGDAALGRTETKTGILLAVFSPILTIGVAVLPRAATSLAAILLFWSALTLLAVALLLLLWNVRPRLRGSGFVAIESMTDAELAQHLASAANDPLRWRREQLLVIARLGAKKFRILRAATTLVMTALLLAIAAAIASTVAT
>NZ_CP040605.1|WP_168590144.1|3660073_3660469_+|helix-turn-helix-transcriptional-regulator
MSPQEDQNRRLLRARDAMDRDFARPLDVAALAGIALMSPTHFTRSFRSTFGETPHRYLQRRRIERAMALLRSPSVTVTEVAGQVGFGSLGTFSRTFRAIVGVSPTEYRTSARPLGVPVCFVKAWARPSRFG
>NZ_CP040605.1|WP_168586778.1|3660504_3660969_+|VOC-family-protein
MFTRISIHSVTVLDQQEALDFYVGKLGFEVVSDVDMGFMRWLTIALPSDPERQLLLEVPGPPSLSEAVAAQVRDLVTKGAMGVAAILTTDDCQQTYETLSAKGVEFTEVPTRQPYGIDCALRDPFGNHIRITQLAAQPAEITEADIARWRPEAE
>NZ_CP040605.1|WP_168586779.1|3661155_3661581_+|transcriptional-repressor
MPSIDAAAILRGAALRVTRPRAAVLTMVSDNPHADTDTIATAVRRELGSVSTQAVYDVLRALTEAGLVRRIEPAGSPARFETRVGDNHHHLVCRDCGAIADVNCAVGEAPCLHAEDPHGFVLDEAEVTFWGSCPDCLSGAE
>NZ_CP040605.1|WP_168586780.1|3661615_3663079_+|catalase
MPENNQKPLTTVAGAPVPDNQNSLTAGARGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSGAFGTFTVTNDITQYTSAKIFSEVGKKTDLFVRFSTVAGERGAADAERDIRGFALKFYTDEGNWDIVGNNTPVFFFRDPLKFPDLNHAVKRDPRTNLRNPENNWDFWTNLPEALHQVTIVMSDRGIPASYRHMHGFGSHTYSFINAEGERFWVKFHHRTQQGIKNLTDAEAEALVGKDRESHQRDLFEAIENGDFPKWKLYVQIMPEADADTYKYHPFDLTKVWSKKDYPLIEVGEWELNRNPDNYFADVEQAAFTPANVVPGISFSPDKMLQGRLFSYGDAQRYRLGVNHHQIPVNKPKNPVNSYHRDGAMRVDGNQGATPGIEPNSYGRWQEQPAYRDPAQAVGAVADRFNYREDDDNYFEQPGILFRNMSPEQQQVLFENTARAIDGASQATIERHLANCTKADPAYGEGVRKAIEALAASKG
>NZ_CP040605.1|WP_168586781.1|3663194_3663581_+|ankyrin-repeat-domain-containing-protein
MSHGGLTPEQTERVVALAMDLAREGETVQLAEFVDHGLPVDVADQGGNTLLMLAAYHGHAETVRALLDRGANPDLRNERDQAPIAGALFKGADKVVAALRKAGADLDAGTPTARAAATMFGREHLLAD
>NZ_CP040605.1|WP_168586782.1|3663899_3664334_+|YbjN-domain-containing-protein
MATWEDLIAFVRNEYRLVIGEVEDGEPEYQIIEDSGDEVRILVEYDDDRSQIVIVCRELLDGREDWVQVVSVIGRAEGVDLRKLLEELGQTSVVCGAVIIGEHVVLRHSLPLLNLDINEFTDPLNFVAETADHLEEVFFRNDDY
>NZ_CP040605.1|WP_168586783.1|3664479_3664935_+|MarR-family-transcriptional-regulator
MGSVDDAVEIRAHGRRTLAALHGTLETTLEKALQAEHGLSVVEYTTLDALGRQDGRHMRTQQLARATELSGSATTRLVNRLDDRQLLTRVLCKDDRRGIYTELTGSGRALLEKARPTYDEALEKALAEAEQVPELTPLVAALHNLPQRPGG
>NZ_CP040605.1|WP_168586784.1|3664941_3665700_+|protein-phosphatase-2C-domain-containing-protein
MQVNHATIATPGRANEDYLATGPDWALVLDGATQPSGVDSGCAHDVPWLVRRLGGELALRLAVSGGTAADVLADAIQATCAAHADTCDLQNPSSPSATAALLRLRGDDLEYLVLADSPIVLDVAGETRPIIDDRLEHLPSYTVEAVRDQRNRPGGFWVASTKPEAAHEAVHGVVPAADVGRAVLLTDGASRYVERFGLGDWSDLLDLVEHTGPAELLRRVRAAEAAETPDERRRHRGKPQDDATAVFLRFSA
>NZ_CP040605.1|WP_168586785.1|3665689_3666181_-|hypothetical-protein
MTATEDAWKALQHSNDLIKVADTKAATMFAAGGVLGGILLRALPTQQLWLADWLHVGLLLISTGSVSASILFALWVFVPRLRTEASRSVLFFDNVARQYSKAVDFVPTYRTTLGDAARLEESLAAQFWATSRIAQRKFRNVTPAIWLFGIALITALLAGIVMR

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Crispr_ID: NZ_CP040605_16

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_16

3837671-3837750

Orphan

Consensus_repeat	Method
ACCGGCCGGGCACACCACCACCG	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NZ_CP040605_16

>merge|NZ_CP040605|16|3837671-3837750|CRISPRCasFinder
ACCGGCCGGGCACACCACCACCGGCATATCCCGGTGGGGTACCGGGTGTTGACCCGGACCGGCCGGGCACACCGCCACCG

>NZ_CP040605|16|15|3837671-3837750|CRISPRCasFinder
ACCGGCCGGGCACACCACCACCG	GCATATCCCGGTGGGGTACCGGGTGTTGACCCGG
ACCGGCCGGGCACACCGCCACCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168586914.1\|3833700_3834297_+\|GTP-cyclohydrolase-I-FolE	unknown	unknown	gnl\|CDD\|376498
NZ_CP040605.1\|WP_168586919.1\|3848444_3848606_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586922.1\|3852621_3854298_+\|energy-dependent-translational-throttle-protein-EttA	unknown	unknown	gnl\|CDD\|236992
NZ_CP040605.1\|WP_168586910.1\|3829330_3830659_-\|2-hydroxycarboxylate-transporter-family-protein	unknown	unknown	gnl\|CDD\|377030
NZ_CP040605.1\|WP_168586921.1\|3852069_3852480_+\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|236092
NZ_CP040605.1\|WP_168586924.1\|3862665_3863097_+\|acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|223894
NZ_CP040605.1\|WP_168586916.1\|3835309_3835582_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586925.1\|3863089_3863731_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168590159.1\|3834298_3834679_-\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168
NZ_CP040605.1\|WP_168586915.1\|3835137_3835311_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586912.1\|3831530_3832766_+\|sodium:proton-exchanger	unknown	unknown	gnl\|CDD\|223604
NZ_CP040605.1\|WP_168586918.1\|3847935_3848205_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168586923.1\|3854405_3857327_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236766
NZ_CP040605.1\|WP_168590160.1\|3849246_3849795_-\|DUF3558-domain-containing-protein	unknown	unknown	gnl\|CDD\|378803
NZ_CP040605.1\|WP_168586920.1\|3849925_3851947_+\|bifunctional-copper-resistance-protein-CopD/cytochrome-c-oxidase-assembly-protein	unknown	unknown	gnl\|CDD\|378238
NZ_CP040605.1\|WP_168586911.1\|3830885_3831263_-\|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|197713
NZ_CP040605.1\|WP_168586909.1\|3828140_3829316_-\|CoA-transferase	unknown	unknown	gnl\|CDD\|224717
NZ_CP040605.1\|WP_168586908.1\|3827349_3828141_-\|CoA-ester-lyase	unknown	unknown	gnl\|CDD\|225184
NZ_CP040605.1\|WP_168590161.1\|3857720_3862601_+\|NAD-glutamate-dehydrogenase	unknown	unknown	gnl\|CDD\|377452
NZ_CP040605.1\|WP_168586913.1\|3832825_3833530_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|225222

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168586914.1\|3833700_3834297_+\|GTP-cyclohydrolase-I-FolE	gnl\|CDD\|376498	pfam01227, GTP_cyclohydroI, GTP cyclohydrolase I. This family includes GTP cyclohydrolase enzymes and a family of related bacterial proteins.	2.04099e-86
NZ_CP040605.1\|WP_168586922.1\|3852621_3854298_+\|energy-dependent-translational-throttle-protein-EttA	gnl\|CDD\|236992	PRK11819, PRK11819, putative ABC transporter ATP-binding protein; Reviewed.	0
NZ_CP040605.1\|WP_168586921.1\|3852069_3852480_+\|single-stranded-DNA-binding-protein	gnl\|CDD\|236092	PRK07772, PRK07772, single-stranded DNA-binding protein; Provisional.	1.13124e-31
NZ_CP040605.1\|WP_168586924.1\|3862665_3863097_+\|acyl-CoA-thioesterase	gnl\|CDD\|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	3.03724e-23
NZ_CP040605.1\|WP_168590159.1\|3834298_3834679_-\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	2.87497e-10
NZ_CP040605.1\|WP_168586910.1\|3829330_3830659_-\|2-hydroxycarboxylate-transporter-family-protein	gnl\|CDD\|377030	pfam03390, 2HCT, 2-hydroxycarboxylate transporter family. The 2-hydroxycarboxylate transporter family is a family of secondary transporters found exclusively in the bacterial kingdom. They function in the metabolism of the di- and tricarboxylates malate and citrate, mostly in fermentative pathways involving decarboxylation of malate or oxaloacetate.	7.09603e-153
NZ_CP040605.1\|WP_168586912.1\|3831530_3832766_+\|sodium:proton-exchanger	gnl\|CDD\|223604	COG0530, ECM27, Ca2+/Na+ antiporter [Inorganic ion transport and metabolism].	2.72462e-20
NZ_CP040605.1\|WP_168586911.1\|3830885_3831263_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197713	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.	2.31999e-16
NZ_CP040605.1\|WP_168586923.1\|3854405_3857327_+\|hypothetical-protein	gnl\|CDD\|236766	PRK10811, rne, ribonuclease E; Reviewed.	5.46581e-06
NZ_CP040605.1\|WP_168586920.1\|3849925_3851947_+\|bifunctional-copper-resistance-protein-CopD/cytochrome-c-oxidase-assembly-protein	gnl\|CDD\|378238	pfam09678, Caa3_CtaG, Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG). Members of this family are the CtaG protein required for assembly of active cytochrome c oxidase of the caa3 type, as found in Bacillus subtilis.	6.90862e-88
NZ_CP040605.1\|WP_168590160.1\|3849246_3849795_-\|DUF3558-domain-containing-protein	gnl\|CDD\|378803	pfam12079, DUF3558, Protein of unknown function (DUF3558). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 177 to 195 amino acids in length.	1.19382e-05
NZ_CP040605.1\|WP_168586909.1\|3828140_3829316_-\|CoA-transferase	gnl\|CDD\|224717	COG1804, CaiB, Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion].	5.86095e-142
NZ_CP040605.1\|WP_168586908.1\|3827349_3828141_-\|CoA-ester-lyase	gnl\|CDD\|225184	COG2301, CitE, Citrate lyase beta subunit [Carbohydrate transport and metabolism].	2.35909e-70
NZ_CP040605.1\|WP_168590161.1\|3857720_3862601_+\|NAD-glutamate-dehydrogenase	gnl\|CDD\|377452	pfam05088, Bac_GDH, Bacterial NAD-glutamate dehydrogenase. This family consists of several bacterial proteins which are closely related to NAD-glutamate dehydrogenase found in Streptomyces clavuligerus. Glutamate dehydrogenases (GDHs) are a broadly distributed group of enzymes that catalyze the reversible oxidative deamination of glutamate to ketoglutarate and ammonia.	0
NZ_CP040605.1\|WP_168586913.1\|3832825_3833530_-\|transcriptional-regulator	gnl\|CDD\|225222	COG2345, COG2345, Predicted transcriptional regulator [Transcription].	9.23399e-16

>NZ_CP040605.1|WP_168586916.1|3835309_3835582_+|hypothetical-protein
MRSDRAAAWLGSPFGCNAGDGQAEFGQQSADDAEPKVGASVETGCGELVATDPERYAAGETAAETGDPFGRLFGGDVKATAEIHRVSACD
>NZ_CP040605.1|WP_168586915.1|3835137_3835311_-|hypothetical-protein
MQPLWELFRRHHGACALCPQPNTWYSSTAQPARPPRGLDPDVRQEVAAALEALDVWA
>NZ_CP040605.1|WP_168590159.1|3834298_3834679_-|DoxX-family-protein
MTRIVVSFLFIQHGVAGLFGVLGAPYPVPLFAWPSWWAGLIQVVGGALVLLGLFTRPAALVCSGAMAFAYFTVHQPRGLLPILNGGVPAVLYSWFFLLLAILGAGPFALDALLRQARQAPAPTQAG
>NZ_CP040605.1|WP_168586914.1|3833700_3834297_+|GTP-cyclohydrolase-I-FolE
MSAPALHVAHQPDGEIDLAAAEKAAGDLLRALGISTDSESLSGTPGRMARAYAELFTPRPFDLTTFPNEEQYDELVLARAIPVRSVCEHHLLPFVGTAHVGYLPGDRILGLSKLARVVEHFACRPQVQERLTKQVADWLCEQLKPKGVGVVIEAEHTCMTLRGVQATGSNTVTSTLLGTLRQDARSRQEFFALTGVNA
>NZ_CP040605.1|WP_168586913.1|3832825_3833530_-|transcriptional-regulator
MVSSDESAAGSMAAVAVLADDLRRGMFEFIRRARRPVGRDEAAAAVGISRKLAAFHLDKLVDAGLLCARFEPVGGIRKVGRTPKVYEPTDAHIRVSIPPRRPDLLADILLDAVLTEGERETAIESAMRTARERGHLLGAEERLRSRPGRLGAERALTRTEEVLTRYGFEPDRETPTCVRLRNCPFHPLTARSPELVCGLNHAFLQGFLAGLQAWSVEAALDPRPGECCVALRST
>NZ_CP040605.1|WP_168586912.1|3831530_3832766_+|sodium:proton-exchanger
MSTKLLRPLALCGALAVPALVLRFSGLAPSPVLGLLLSGMAVVASSFVLAWAAEAAQVDISGGLAIAILAVIAVLPEYAVDLYFAYTAGSNPEYVAYAAANMTGSNRLLLGLGWSLVVVVALALVKRRTGKSVRELTLESGNRVELGFLAIASMIAFLVPATGQISLLLGFVLLGFFVFYLWKVSRAEAEEPDLVGTAATIGGLPKHVRRPLVIALFVFAAAVIVVCAEPFAHSLIETGTQLGIDQFLLVQWLAPLASEAPEFIVAILFAVRGKGADAIGTLISAKVNQWTLLVGSLPVAYLLGGGGTALQLDARQVEEFLLTATQTVLGVAAVLALRFPRWTAWTLLGLFAAQFALPGQTARYVLCGSYAVIAIAALIRNRHHILPTLAAPFRRQGDDSTAAREPTSAVR
>NZ_CP040605.1|WP_168586911.1|3830885_3831263_-|helix-turn-helix-transcriptional-regulator
MPKNRTPHAAESDLSRRDAEPTGAQLTAAAATFALLASPPRLHLVWLITHGSYDVGTLAKRVGISIATVSQHLSKLRLAGVITARRDGRRHLYSVDDPHVVALVEQIFEHIAPDGTLAPDPPQTR
>NZ_CP040605.1|WP_168586910.1|3829330_3830659_-|2-hydroxycarboxylate-transporter-family-protein
MASPPDAVSAEQVAPTEQPRSFWSVRIGVIPLPFYALLVVVLAVLAWQDDLAADIPTMAALLGVCSYTCYEVGRRIPGFRSIGGPVILVTFLPAFLVAAQWIPADLAKHISTFYKSTNFLYVFIAGIIVGSILSMNRTVLIRGFLKIFGPLAAGSAAALVVGSLVGWAITGDLHRTVFFIVVPVMGGGLGEGAIPLTLGYAQSGAGQAETLLAQVLPVVLLANVCAIVFSSVLSMIGQRFPQTTGFGKIQPAEDEELGLADRGHVAFDIRQLAAAGFMAVALYLLGEATHALFGWPAPIVMLVAAILLKLSRWLPRSLEHHSGLVYDFMSTAVTYPLLFAIGVSSTPWNELFKAFTVGTVITIVATVVTMMATAFVVGRWMGMYPVDTAIVVGTHTGMGGTGDVAILSATRRMALMPFAQIATRIGGAITVTIALIAHANLY
>NZ_CP040605.1|WP_168586909.1|3828140_3829316_-|CoA-transferase
MRPLRGVTVVALEQAIAAPYATRQLADLGARVIKVERPGAGDFARQYDSRVNGLSSHFVWVNRSKESLTLDIKDPRGMAVLRQLLGTADVFIQNLAPGAAARMGLGAEELQAGNPGLVVCDISGYGRGGPYESMKAYDLMVQSEAGLLSVTGSGDDMAKVGISVSDISAGMYAYSSILAALLERANTGKGAHIDVSMLESTVEWMGFPLYYTYDGAEPPPRAGAAHATIYPYGPFTAGDGKVIMMSIQNEREWRAFCDRFLGQPELAEHPDYAGNANRNANREVLGRIIAARFADLTGDEATALLTSVPVACARVNTLADVWEHPQLAARGRWHEVQTPRGPVPALAPPGPVNPEPRMDPVPDVGEHTRKILAELGRGESDVDDLIRDGVV
>NZ_CP040605.1|WP_168586908.1|3827349_3828141_-|CoA-ester-lyase
MQNAVTWLFVPGSRPERFAKAAGAGADVVIVDLEDAVPADAKAAARKNLRSAWPIGSSVAVRINGRSSPEFDDDVALCRKLGPAAVVLPKTESAQDVAVTAEATGSPVLGLVETARGFINLGEICTAPGLVRLVFGSIDLALDLGVTVDAALDTSRSDLVRWSAACGLPAPLDGVTPSINDTEAVERDSRRAKDWGFGGKLCIHPAQLPVVRDAMRPSPEELAWARRVVEADEQALGAAVSLDGAMIDRPVVERARRLLRAAE
>NZ_CP040605.1|WP_168586918.1|3847935_3848205_+|hypothetical-protein
MQLCQRVGDNALSAEMLAGVSHQAAHAHDGAVSVGLARAARDTAAGTGFAALESETAVMEAHGLALVRDKRGSMWRSGPLRTRSAERTR
>NZ_CP040605.1|WP_168586919.1|3848444_3848606_-|hypothetical-protein
MPLLLRSPRSTCWRNVEADPHRGQFFAKLGHHRHGWMPVKALGEVLQVEPGTR
>NZ_CP040605.1|WP_168590160.1|3849246_3849795_-|DUF3558-domain-containing-protein
MLLLCTVTGCASKIPGEPIPAAGFHENHPAEPAQPRSTVAAQARIAIPRNFDGIDPCTLLTPADLAVVGGPAGPPHPDNPIAGTCSQALASGPENTAAAGFYEPYEVASGRQPRGVQLDIEGHSAWLYCELVDSHQTCTAATAIRSDRTLLTMLSMHGAAAADTAEQLGKLTAAALHKLPPT
>NZ_CP040605.1|WP_168586920.1|3849925_3851947_+|bifunctional-copper-resistance-protein-CopD/cytochrome-c-oxidase-assembly-protein
MPSETPAPAPERRTSSTVGVLVITAGVLAALIAAVLTALSAGASYVLLGLPDPGPITQYGLPVVRVVAESGAVVCIGSLLLAAFGIPAKRSGPLAADGYATVRTASWAAAVWCVGAALMVPFIAAEAAGRPVGDVLSVDVLFGLVDALEEAKAWALTALIAFVVALVCRVVLSWGWTVVAFVLGLAGLFPVIATGHSASGGAHDIATNSLLVHLFGAVLWVGGLVALLAHAARRGAHLPLVARRFSQIALVCWIAMALSGVINSLVRVSPADLFTSTYGFLLVLKVVGLVALGAFGYFQRRGVVRRLDDGPGAAALLRLGAAEVLIMFATIGVAVALGRTPPPEGSKAVPGRTELLIGYPLDAPPTLFRLLFDMRFDLIYGTFAIALAGLYLWGVYRLRKRGDAWPVGRTIAWLCGCATIFMATSSGIGKYAPAMFSVHMGQHMLMSMLAPVFLVLAGPTSLALRVFKPAGKTQPPGPREWLLAFVHSPVARVLTNPFVALALFVGSFYALYFSGLFDVALTQHWAHLAMNAHFLLVGYIFYWPVIGIDPAPRPLPSLGKVGLVFASMPFHAFFGIVLMMSQTVIGASFYRGLDLPWMTDLLADQRLGGGLAWASGEVPLVVVMLALLIQWSRADSRVARRIDRKADADGGADLAAYNEMLRQLAEKDTPRRK
>NZ_CP040605.1|WP_168586921.1|3852069_3852480_+|single-stranded-DNA-binding-protein
MFETQVTVVGYVLTDPVVRETQNGHRVVNFRVVAASRRLDRDTGEWVDGDRFYATVNCWKRLADGVASALGKGDPVVATGRLRTRDYESGGQWRTVVELEANAIGLDLARGAPPEVPGMSRPRPGSERGLVSVPGG
>NZ_CP040605.1|WP_168586922.1|3852621_3854298_+|energy-dependent-translational-throttle-protein-EttA
MAEFIYTMKNVRKTHGDKVILDNATIQFYPGAKIGVVGPNGAGKSTVLRIMAGLDQPNNGEAFLTPGYTVGIQQQEPPLNEEKTVLGNVEEGVGEIKQKLNRFNEIAELLATDYSDELMEEMGKLQEDLDHADAWELDSQLEQAMDALRCPPPDAEVKNLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVLWLEQHLATYPGAVLAVTHDRYFLDNVAGWILELDRGRTFPYEGNYSTYLEKKAERLAVQGKRDAKLQKRLKDELEWVRSNAKARQTKSRSRLSRYEEMAAEAEKTRKLDFEEIQIPPGPRLGNVVVDVENLKKGFDDNLLIDGLSFTLPRNGIVGVIGPNGVGKTTLFKTIVGLEQPDSGTVKVGDTVKLSYVDQNRANIDPNKNVWQVVSDGLDYIQVGQVEMPSRAYVSAFGFKGPDQQKPAGVLSGGERNRLNLALTLKEGGNLILLDEPTNDLDVETLSSLENALEQFPGCAVVISHDRWFLDRVATHILAWEGDDEDPAKWFWFEGNFGGYEENKLERLGPDAARPHRVTHRKLTRG
>NZ_CP040605.1|WP_168586923.1|3854405_3857327_+|hypothetical-protein
MLSDRAVALARHAGDRAIRLRAEALALFASNRLGRGVAASGRALAAVRDAVAAGDAEVEAELRVELAWCASSAGSGEVAVRVLNPVLEQDRIAPEVRAHALLALAASLPAHGQDGDRSEALDEAEWLYEACGLSRDTARLLNARVRAARAAHRRRLGEFDEAIAVADAGLALLGQLGDPAADSGEMRARLVLERVLSLLELGRRPEAVQATESVLAQPVRAAAAGPVGWLGLAMATRVHLPDGNHGAAVRTLNDTAAISERHKLDGLLAETLNTLSHVHERGAEFPEALRALRGAYSADRRWRATVHTARVRLLAEYPVHSGGVEVPRQSSASPDPGPAGPEAAVLGLVGTRAAEPEQPEPAAPQPRRPEKGLREQGFPEQGFPEPSEPEQATSRHRSGYEETHDAARRLMETLTNRAAELREGGHRRQEPPEPRTAEEPEATEGAASQTVVFDSWALESQAAGIGQQDWQAAAEPADAQNARTIQVPEVEAVAFAEPADQGFPSHEPVSEEHAEPVATTAQASWWPSENPEQPQNAERTVPEVPVTHEPQPAESQQRLSVEFRPAESPSVEPLPSTAVLAAAADDIYRPVPAADDDHGAMDATAILPVIGGPAGSAEPVDLPGTGSAARNRPEESSPEGLHPRESRYGLSQYGRDLPGNDLPAIEQPGNYQVHDAPQDEPAHGSRETEPAAETPTGGTPAAEVTPASGTSVSEAPPGGTQRRQGGRRSRGKSLAEIRASLQLSAEPRSRRRARHADLAEPVESSDARETSDPAVAPPTPAAEVLGRHRQDWATEPNLLVVERHRTEELVGDGEAAEPPAAEPSAAEPPAAEPPAAEPPAAEPPAAEPPAVEASIVVPLAAELATAEQPGEEAPAAEPAAESAGEDAGPQGKIGLAELLTEALMAYESGRRAQPEAEETAPSGRHSEARVSGITGLPQVSHATHLSTSDDRGSGLAARHRRPAIDSTAVDPLF
>NZ_CP040605.1|WP_168590161.1|3857720_3862601_+|NAD-glutamate-dehydrogenase
MAKRRLLDRAVEFAPELAELLHAYYRHVPAEELVDDEPTDLVGALRSHYRLASTRVAGRPLVQISNPERTDDGWQSQATVVQIVTDDMPFLVDSVIAELGRDGAEVQRIIHPIFVVRRDVAGELQEVLPGADPAEPPADAIAESWMFVEVDRVVDEERLSVLQHGLTDVLNDVREVVEDTERMHATAKALADELERTPPRLPGEDVHDGVELLRWLAEGHFTFLGYRHYELVDGSGPALQAVLASGLGVLRSDSVAARSLTAGPDGRANALSKDLLVLTQASAPSTVHRPVHPFYVGVKTFDESGQVNGEHRFLGLFNTAALHEDVLDIPFIQRRVREIIHRAGFPMESYSGQRMLEEIQNYPRTELFSTDPDTLQETITGVLALAERRKLKPFLRRDPYGRFYSCLVYLPRDRYTTSSRLAMQEVLLEELHGTGLEYSTRVGESTLARVHFVVHTDPENQVEPDLARIQRRLDEAIHTWDDQMIEEVDAEQSGAGRDGHATRSLSEAISQIGQSCASSFPESYKEDFTAAEGLADLRRLESLSDPRDLKMSFYAPRDASAGQRRFKLYVGGRVTLSRVLPVLQSMGVEVVDERPYEVIVGDTDQQYWIYDFGLRLDPSLLDSATSGGLLDTLRQRFEDAFRAAWLGDAEVDRFNALVLRAGLNWRQASVLRAYAKYLRQVGIAYSQDYIEDAILAHRTTTTTLVRLFETRFDPALGADDRASREADLTEDVTKLIDEVTSLDADRILRSYLRLIRATLRTNYFAGDEQRERSYLALKLEPREIPGLPEPRPQFEIFVYSPWVEGVHLRFGSVARGGLRWSDRREDFRTEILGLVKAQAVKNAVIVPVGAKGGFVVKRPPTPTGDPAVDRKATLDEGIACYRMFISGLLDLTDNLVGGEVAPPRDVVRHDGDDTYLVVAADKGTAKFSDIANDVAKSYGFWLGDAFASGGSVGYDHKAMGITAKGAWESVKRHFCELDVDTQSEDFTVVGIGDMAGDVFGNGMLLSEHIKLVAAFNHMHVFIDPAPDPAVSFAERRRLFELPRSTWDDYDRTKISAGGGVWSRSLKSIPLNPQIRQALGIDESVRQLAPAELIKRILLAPTDLLWNGGIGTYVKAATETHAEVGDKANDPVRVNGADLRVKVVGEGGNLGLTQLGRIEFARAGGKVNTDALDNSAGVDCSDHEVNIKILLDHLVADGKLTGEQRNELLADMTDEVGELVLADNHSQNAVLGISRAHAAPMVSVHARQVTALEKTTGLDRKLEALPTSKEFRDREKAGEGLSSPELATLMAHVKLSLKRDVLASGLPDAEAFSGRLPEYFPKPLREQYGDAIAAHPLRREIITTLLVNEMVDGAGISYAYRLSEEISASTTDAVRAFAVVTNVFGLRELWAQIDALGGSMPSSVADELVLESRRLLDRAARWMLTNRPQPLAIGAEISRFQPVVAELSDSVRGLLRGRAAEGATEMIDHCVAAGVPEDLAERVGVLLDSFALLDIREIAELAERDAGVAAERSPRESADLYYSLAEHLDVERMLLAVNELERGNRWHSLARLALRDDFYATLRAITIDVLRTSDPEDNPEEKIARWESTNESRLARANSSLEQIKNSGRLDLATLSVAARQLRSMVR
>NZ_CP040605.1|WP_168586924.1|3862665_3863097_+|acyl-CoA-thioesterase
MGAFVAEVALRWSDMDAFGHVNHARTITLLEEARAELLFTEAERQGLLGMAEGMVVARVVVDYHSPLLYRARSLQVRMSVRELKAASFIVDYTAYAQEAVATAETLMVPYDLRAGRPRRLTSEERDFLAEWQLEPAKSELGRA
>NZ_CP040605.1|WP_168586925.1|3863089_3863731_+|hypothetical-protein
MPELRMPDPVEREDLGAFVARAVRLDGQALVRLRNRPGAGRVDVWAATPFDALSTRSVEGEVEPSDVTVSGSGLLAALTVAGAPVMDPGPPRDLMWRSELPPFEGWHRVDDLPAKLVGEVAERGIDVAKDNVGPKGTPPASLLDQEVFTVSGSGFEVKVPLRCLFVLSGMGFLVPKPAESEIVRVSATDAWLRLDSRYGAVVRRRHALLPLLI

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Crispr_ID: NZ_CP040605_17

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_17

5328933-5329012

Orphan

Consensus_repeat	Method
ACCGGCCGGGCACACCGCCACCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040605_17

>merge|NZ_CP040605|17|5328933-5329012|CRISPRCasFinder
ACCGGCCGGGCACACCGCCACCGGCATATCCCGGTGAGGTGCCGGGTGTTGGTCTGGACCGGCCGGGCACACCGCCGCCG

>NZ_CP040605|17|16|5328933-5329012|CRISPRCasFinder
ACCGGCCGGGCACACCGCCACCG	GCATATCCCGGTGAGGTGCCGGGTGTTGGTCTGG
ACCGGCCGGGCACACCGCCGCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168587885.1\|5303929_5304232_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|181235
NZ_CP040605.1\|WP_168587890.1\|5333441_5334089_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168587893.1\|5338440_5339214_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212491
NZ_CP040605.1\|WP_168587896.1\|5341182_5341938_+\|IclR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224332
NZ_CP040605.1\|WP_168587887.1\|5306031_5306448_+\|DUF4442-domain-containing-protein	unknown	unknown	gnl\|CDD\|373120
NZ_CP040605.1\|WP_168587891.1\|5336047_5337265_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239443
NZ_CP040605.1\|WP_168587888.1\|5319445_5325646_+\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|225858
NZ_CP040605.1\|WP_168587897.1\|5341927_5342542_+\|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase	unknown	unknown	gnl\|CDD\|188632
NZ_CP040605.1\|WP_168587898.1\|5342717_5344085_+\|MHS-family-MFS-transporter	unknown	unknown	gnl\|CDD\|340927
NZ_CP040605.1\|WP_168587895.1\|5340202_5341198_+\|sugar-kinase	unknown	unknown	gnl\|CDD\|238571
NZ_CP040605.1\|WP_168584373.1\|5332335_5333226_-\|IS982-family-transposase	unknown	unknown	gnl\|CDD\|376573
NZ_CP040605.1\|WP_168584616.1\|5306482_5307319_-\|transposase-family-protein	unknown	unknown	gnl\|CDD\|372577
NZ_CP040605.1\|WP_168587882.1\|5300943_5301150_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168587886.1\|5304569_5304731_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168587894.1\|5339216_5340206_+\|hydroxyacid-dehydrogenase	unknown	unknown	gnl\|CDD\|240642
NZ_CP040605.1\|WP_168587884.1\|5301902_5303102_-\|metallophosphoesterase-family-protein	unknown	unknown	gnl\|CDD\|277329
NZ_CP040605.1\|WP_168584597.1\|5325783_5326182_+\|IS200/IS605-family-transposase	unknown	unknown	gnl\|CDD\|376616
NZ_CP040605.1\|WP_168590336.1\|5303292_5303667_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366359
NZ_CP040605.1\|WP_168587883.1\|5301146_5301692_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168587892.1\|5337397_5338444_+\|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl\|CDD\|176195

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168587885.1\|5303929_5304232_+\|hypothetical-protein	gnl\|CDD\|181235	PRK08118, PRK08118, DNA topology modulation protein.	9.7961e-22
NZ_CP040605.1\|WP_168587898.1\|5342717_5344085_+\|MHS-family-MFS-transporter	gnl\|CDD\|340927	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli shikimate transporter (ShiA), inner membrane metabolite transport protein YhjE, and other putative metabolite transporters. ShiA is involved in the uptake of shikimate, an aromatic compound involved in siderophore biosynthesis. It has been suggested that YhjE may mediate the uptake of osmoprotectants. The ShiA-like subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.43348e-146
NZ_CP040605.1\|WP_168587893.1\|5338440_5339214_+\|SDR-family-oxidoreductase	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.61696e-54
NZ_CP040605.1\|WP_168587896.1\|5341182_5341938_+\|IclR-family-transcriptional-regulator	gnl\|CDD\|224332	COG1414, IclR, Transcriptional regulator [Transcription].	6.53433e-63
NZ_CP040605.1\|WP_168587887.1\|5306031_5306448_+\|DUF4442-domain-containing-protein	gnl\|CDD\|373120	pfam14539, DUF4442, Domain of unknown function (DUF4442). This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 139 and 165 amino acids in length. There is a conserved PYF sequence motif. There is a single completely conserved residue N that may be functionally important.	2.20361e-07
NZ_CP040605.1\|WP_168587891.1\|5336047_5337265_-\|hypothetical-protein	gnl\|CDD\|239443	cd03327, MR_like_2, Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues, a Lys-X-Lys motif and a conserved histidine-aspartate dyad. This subgroup's function is unknown.	3.27785e-122
NZ_CP040605.1\|WP_168587888.1\|5319445_5325646_+\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
NZ_CP040605.1\|WP_168587897.1\|5341927_5342542_+\|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase	gnl\|CDD\|188632	cd00452, KDPG_aldolase, KDPG and KHG aldolase. KDPG and KHG aldolase. This family belongs to the class I adolases whose reaction mechanism involves Schiff base formation between a substrate carbonyl and lysine residue in the active site. 2-keto-3-deoxy-6-phosphogluconate (KDPG) aldolase, is best known for its role in the Entner-Doudoroff pathway of bacteria, where it catalyzes the reversible cleavage of KDPG to pyruvate and glyceraldehyde-3-phosphate. 2-keto-4-hydroxyglutarate (KHG) aldolase, which has enzymatic specificity toward glyoxylate, forming KHG in the presence of pyruvate, and is capable of regulating glyoxylate levels in the glyoxylate bypass, an alternate pathway when bacteria are grown on acetate carbon sources.	8.71416e-50
NZ_CP040605.1\|WP_168584373.1\|5332335_5333226_-\|IS982-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	2.38215e-05
NZ_CP040605.1\|WP_168584616.1\|5306482_5307319_-\|transposase-family-protein	gnl\|CDD\|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.95997e-24
NZ_CP040605.1\|WP_168587895.1\|5340202_5341198_+\|sugar-kinase	gnl\|CDD\|238571	cd01166, KdgK, 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources.	9.51259e-81
NZ_CP040605.1\|WP_168587894.1\|5339216_5340206_+\|hydroxyacid-dehydrogenase	gnl\|CDD\|240642	cd12165, 2-Hacid_dh_6, Putative D-isomer specific 2-hydroxyacid dehydrogenases. 2-Hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	2.31779e-96
NZ_CP040605.1\|WP_168587884.1\|5301902_5303102_-\|metallophosphoesterase-family-protein	gnl\|CDD\|277329	cd07383, MPP_Dcr2, Saccharomyces cerevisiae DCR2 phosphatase and related proteins, metallophosphatase domain. DCR2 phosphatase (Dosage-dependent Cell Cycle Regulator 2) functions together with DCR1 (Gid8) in a common pathway to accelerate initiation of DNA replication in Saccharomyces cerevisiae. Genetic analysis suggests that DCR1 functions upstream of DCR2. DCR2 interacts with and dephosphorylates Sic1, an inhibitor of mitotic cyclin/cyclin-dependent kinase complexes, which may serve to trigger the initiation of cell division. DCR2 belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	5.9933e-32
NZ_CP040605.1\|WP_168584597.1\|5325783_5326182_+\|IS200/IS605-family-transposase	gnl\|CDD\|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	8.82524e-52
NZ_CP040605.1\|WP_168590336.1\|5303292_5303667_-\|hypothetical-protein	gnl\|CDD\|366359	pfam00891, Methyltransf_2, O-methyltransferase. This family includes a range of O-methyltransferases. These enzymes utilize S-adenosyl methionine.	1.06985e-18
NZ_CP040605.1\|WP_168587892.1\|5337397_5338444_+\|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl\|CDD\|176195	cd08233, butanediol_DH_like, (2R,3R)-2,3-butanediol dehydrogenase. (2R,3R)-2,3-butanediol dehydrogenase, a zinc-dependent medium chain alcohol dehydrogenase, catalyzes the NAD(+)-dependent oxidation of (2R,3R)-2,3-butanediol and meso-butanediol to acetoin. BDH functions as a homodimer. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. The medium chain alcohol dehydrogenase family (MDR) have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Sorbitol and aldose reductase are NAD(+) binding proteins of the polyol pathway, which interconverts glucose and fructose. Sorbitol dehydrogenase is tetrameric and has a single catalytic zinc per subunit.	2.00674e-81

>NZ_CP040605.1|WP_168584597.1|5325783_5326182_+|IS200/IS605-family-transposase
MVVTLRSNANITFQCAFRVVWCPKYRRRVIGGRMEERLKQLIREVVEEKGAWLVELETMPDHVHVLVEVDPQYGVHKLVKAIKGRSSRVLREEFPWLRSKLPTLWTNSYFVATVGGAPLSVIKRYVEQQKAR
>NZ_CP040605.1|WP_168587888.1|5319445_5325646_+|SDR-family-NAD(P)-dependent-oxidoreductase
MNENDKLSEYLRRVTAELYDVRGRLAETETRLHEPIAIVGMACRYPGGVNSPEDLWSLVADGRDVISGFPEDRGWDLEHLYHPDPDNHGTSLTDQGGFLYDAAMFDAEFFGISPREALAMDPQQRLMLEVSWEALERAGIDPVSARGSNTGVFTGVAHNDYGGRFMAGGADGGELEGYFGSGSAHSVVCGRISYVLGLEGPAVTVDTACSSSLVAMHWAASALRAQECDLALAGGVTVMSTPSVFVEFSRQHALSPDGRCKSFSSTADGTGWSEGAGVLVLERLSRARKLGHRVWGLLRGSAVNQDGASNGLTAPSGPAQERLIRAACADASVSGVDVVEAHGTGTRLGDPIEAQALLATYGRDRGDRDPVWLGSVKSNIGHTQAAAGVAGVIKMIMAMQQGTVPPSLHVDEPSREVDWTAGAVRVATKTVPWPTTGDRRRAGVSSFGVGGTNAHVIVEEAPETPAESQLGSQPEPSGTLVPWVLSGASEQAVRSQAGRLRAMLEQTPGWSLTDVGWSLHTTRALLDSRAVVFAADPEEARRGLAALATGRALPGVIEPASEAPTRSGVGFVFSGQGAQRLGMGHELAARFPVFASAWDEVCRSLAEFGGVPGVEEVLWGTADAATVDDTLYAQTGLFAFEVALTRLLESWGVRPDYVMGHSLGEVTAAYVAGTWSLADACRVVGARARWMRQAPSGGAMVALEARPEDVADVLAGTPVVVAAVNGPQAVVVAGPDDAVRKVADRFAALGRRTKRLRTSHAFHSPDMDSVLPGFQAEIEAVTFHTPDIPVISNVTGELADPDSLTRPSYWAEHIRATVRFGQGARALLDTGVGQVLEVGPDASLNGLVGDLTRQGQRAFAAMRAGRPETAELLTSVAQLFAHGVAVDWSWCWADAAPRRVDLPTYPFQGRRYWMDVPPATAGDMTTAGLEGGGHPLLGARLDLAGDGTTLFTSRWSVADQPWLADHQVSGRVVVPGTTFVELALHAARLTGCESVRELVHHVPLILEPDEAVSVQVRLDAADEDGTRPIGVSSRPESADEQDAWVLNTTGVLAGSTPGDLGKFAFAAAWPPSGAVQLDLDGLYEEHALTAGFDYGPTFQGVSAVWHLGDDIYAEITSPEVLDTLGYCLHPALLDATLHPGLIASEQLGLRAAGLPFVWADITVHRHGATRLRARVRRHDDHRISIDVATAEGAPVVAVDSLTLRPHQLATRDRAGTRSVLRLTWSAAPVEVHSRTFTWQVATKDSFALESSLAAVGVVCIGTSTESGDLHAQVTVACVDGTVDQSPHDCAARTLTIVQQWLSSVSDPHARLIVVTRGAVATRSTEAAIDLAAATARGLLRSAQTENPGRITLVDIDEGNGIGEALLFAAETDEPEVAVRAGRILVPRLAIETPSGRTAAAGEAGNAINPAGTLLVTGGTGTLGGILVKHLVSAHGVRHLVLTSRRGLDTPGSAQLCEELRELGAEVTVVACDTADREALRVLIDSIPTGRPLAGVIHLAGITDDSVVTALGKEQLQRVLRPKVDGAWNLHELTKDKDLSVFVLFSSASAILGGAGQGNYAAANAFLDALAGHRRQQGLAAVALAWGLWAKHSEITAKLSESDRARLADSGMLPLDDDEAMALFDAAMRSSESLLAPIAFDAAATRKNLDTSPAPILNTVAGTRKRVVTAKSKAGKPALLGRLAGLSDSERVSAVAQAVRAEVASVLGHADTDEIKDTAMFRDLGFDSLASVDLRNRLSTLMGLRLPATVVFDYPNVQALADYLVSRIETIGDEPGGPVLEQGADTRAHPHAEQEDTVSALFRSAVGEGRAAEALQLIGAVAALRPMFGGTDTRATSPLKPASLSQGGRGPELICLPSLGAMSGIQQYFRLAEALGATRALSSFSVPGYLTGEELPDSLDTLASLLATSVKRHLDRSKEYVLLGHSSGGWIAHLAAERLAREGMPPVGLALLDTYLPGSDETAAILPELIADMVESPAGTAPLEQVRLTAMGWYFRIFANWEPTSLPAPTLFARPSDPFREHLREAGWQATWPLEHSSAHVAGNHFTMVGEEVVETAQAVSTWLDSL
>NZ_CP040605.1|WP_168584616.1|5306482_5307319_-|transposase-family-protein
MVTYSAKLDVPRELVVFLSRLLAGERRRKGTRKGRRALTTFWQAVLVLRWFRDDTDITKLARDHGVARATGYRYVDEGIKALAAQAPDLHDALQRAKDNGDAYLILDGKNFSSDRLGEKTTSAKGAEIDLWYSGKTREQAGNIQALTDPDGFPLWASDVEPGSIHDITAAENHVLGALYWAYSQLNLPTLADGGYQGAGAGVLTPIKRPKTSKGRPLDVDNQTYNKLLRGLRALGERGFALLTGRWRVLRHFTTSPRKIGLIVKAALVLTQFEHGRLA
>NZ_CP040605.1|WP_168587887.1|5306031_5306448_+|DUF4442-domain-containing-protein
MTVLGSPTKVRLRLNLWSPFLFLAFGLSDIAEGWSKVNVVHGVGRFDRNANGSAFGGALFVMVDTFFPLMMMHHLGRGYRVWSRAATVDFVAPGRGNGGLRCLLNRLRWSAFECRLMLTNSRARGIARKFVRLAEGWP
>NZ_CP040605.1|WP_168587886.1|5304569_5304731_-|hypothetical-protein
MEKQYSSAGASESGSADLLVGDALQHRPQQLDEGDLALAVDHHVHGDVARQHP
>NZ_CP040605.1|WP_168587885.1|5303929_5304232_+|hypothetical-protein
MLTARPEWIIDGNYAGTMPIRLAAADTVIFLDIHPLLCLWGILQRRLQHLSAGLGVRSWSGAPSGWAFARVLALRCVALVGHGDFDQALSGSTERIRKFH
>NZ_CP040605.1|WP_168590336.1|5303292_5303667_-|hypothetical-protein
MPTQSRGILFDRPEVVEQARQAFIGQGLASRVRFVGGSFLEAVPDGGDLYLLKNVLCDWDDENCAQILSRCRDAVDADTPLVFVDWRSARHRRQNRRSNEPTENAALRTDHFANRRCSGTPTYT
>NZ_CP040605.1|WP_168587884.1|5301902_5303102_-|metallophosphoesterase-family-protein
MNEQSDLSATPESTEAGVGRRQFMALGGLGAATVALGATTPAASAAPAPSAQTANLRFRADGTYKIVQFNDTQDDERIDRRTLELMNAVLDDQRPDLVILNGDNITSGCDTELEMRQAMNNIVQPMEERKIPWAITYGNHDEDSTAKGGLDESEMLEFYRSYAYNVNELGPRGVTGTGNMNLFVHGSRGNDPKFNLWLLDSGRYAPGNIAGQNFAGYPTWDWLRMDQVAWYFQRSVEIERQVGRKVPGLMFIHIPLWEYRFMWFGSVDGRTDADHARGVARHGIVGERNEAECPGPFNSGMFNAILTRGDVKGVFCGHDHINTYHGNYYGVLLGYAGSTGFGTYGLSGAERNRLRGARVYTLNENTENVLDSTYMVFAKDYGIDLTANDQSIDPMPLPS
>NZ_CP040605.1|WP_168587883.1|5301146_5301692_-|hypothetical-protein
MRTIRRLENNSSGNPRIGTVQLLAKALELGPEDYQRLLATTGSAPPPVEAEAPPEAQPPRPQLRPQPPVRRTARQPALDEAAEQLAQAVERRWQREEEHRRVHDPFQLPVRFQPVADGLIDPRPGAAQQLTGGIGDLADSYRRIPSGHLVVLGRPGSGKTILALRSCWTTCAVAKPTSPSR
>NZ_CP040605.1|WP_168587882.1|5300943_5301150_-|hypothetical-protein
MIFDIGSWDPIATALRDCLGLGGEVPVVVQMLATDDGGLTEFGEAVPAVIPECVQRSARSIGGVTPSV
>NZ_CP040605.1|WP_168584373.1|5332335_5333226_-|IS982-family-transposase
MTKELNTLLTALYVLIDDHVVPARTGRGRRPLFTDSELLTLAVAQVLLRYNGERRWMRHVHSNPELLAMFPHVPRQPGYNKRLRNAQPLLCKAIITLAACCPSWFDDLWITDATPVPCGMSRETVKRSDLAGHANYGYCASHSRWYWGLKLYLVCTGDGMPVMWCLADPKIGEREVLAALLDNNHYLIRNGQILLADKGFSGKEFKKLTESKQLRLLRPDRKDETYACGNLGGVRQWIESVNQTLKSQLGLEQHGGRTPAGVFTRVAQRLLAMAAGIWHNWETGATSKRSLIAFDH
>NZ_CP040605.1|WP_168587890.1|5333441_5334089_+|hypothetical-protein
MVSPDSVTQSGEGSRAAPSVDRDPVAVLPEGLPADTVRAPVSAEVVAGGGLAKFVQGVADSTGGPVLLVSPSNPTAGVVVTPDQGSALAQDMGRNVVAMTTPGQAGREPRWTVFAADGSARPLARPVAEVLADGRGVAGLADASAAVPAASGGKRVARGTENLTARVELSASCTVILVAQGVDLDDLVPVTHRQQAQHRERVGHIQVGQSQQHSR
>NZ_CP040605.1|WP_168587891.1|5336047_5337265_-|hypothetical-protein
MEITRVEARHVARSMWGNFWQQQKSVRGPNPMSQFPQRGNGWSWYTWPQGIVAVRVTLADGTTGIGYAEDGIGAATTMVTDHLGRIATGLDARATEQIWEQLYRSSIVYGRKGAAIEAISAIDIAIWDALGKTLGQPVYQLLGGYHGKTVRAYASKVQPDDDLSEVRRMARDYTERGYTGVKANWPYGPADGRRGLLANLRYIEAIRDEIGDDIELMSDAYMGWDRAFATDMLRGVAEFDLRWVEEPLIPDDVEGHAALRGLGLVPIATGEHEFTRYGFQHLIDAGAADVLQPDVHRVGGITELRRVCQMASGASIDVIPHVYSAATLHVVLSQPNCTWIEHLTNPSYWGVDQRVEPLFLGEPAVINGHPEFPTEPGIGLHINDKVMPELADWATDEEKLTPSGI
>NZ_CP040605.1|WP_168587892.1|5337397_5338444_+|alcohol-dehydrogenase-catalytic-domain-containing-protein
MRAVSWAGVDRLEQRMVPIPGLGPGEALIKVSRVGICGSDLAIFRGQHARAQPGVIIGHEFCGTVADSNAPGAPPVGSQVAVRPLIVCADRGTVPMCRACASGNSHVCAALGLYGVDEPGGLAEYVAVRADALQPVSPDVAPELTALAEPLAVAVHAVSRSGLRSGDSVAVYGAGPIGLLTALVARYRGAGDVVLVEPNTWRRGVAERYGFTVLPFGAETPAEIRRRSAGNGADIVFDSAGHPAVALQLTETARIQGTIMIVGVYKSPPAVDLRTVNFAEHHVIGTRVYGRADFAAATELIETDALSLSDLPTTTFPLDAATDAFAAAARGEGCVKVLIDPSQNRGIA
>NZ_CP040605.1|WP_168587893.1|5338440_5339214_+|SDR-family-oxidoreductase
MTNTAPARGAWVIGGGSGIGRAIALRLARDGYHVIVSGRREEHLAETVKEITEAGGHADPVPVDVTDDDSVTAAHRTVEERLGTLEVLVCSAGTNVTNRWWSQLSSKDFSRVVDTNLNAVTRCVLTVLPGFRTAGFGQVIVVSSWAGWRYMSAAGAAYSASKTALGALVETLNDQEGRHGIRATHLCPGEVDTPILQTRPVPPPTEEVERMLSPGDVAEVVGSVVALPANVCVNELVVTPVWNRMYVDTSAYTPTGA
>NZ_CP040605.1|WP_168587894.1|5339216_5340206_+|hydroxyacid-dehydrogenase
MRVAVTDENVWPWLRGSTALANRPIELEYLPGTDRAAVRDRLSGATAYVGVFFDAELARAVGPDFRFLQVTAAGTDHIAIDELPTSVAVCNAYGHGRSIAEHVLMVLLAARRHLLWRDAELRQGRWRTRMVDPTAPVFRTLRDSTVGIIGFGHIGRSIAQLCRAVGMRPIAVRKSASSRDVSDPDAGWVAGLDALGDLLDESDVLVVACPLTDETRGLIAASELKRLGSAATVVNVGRGAVFNESDLYDALRQGTIANAALDVWTTPASADVAPPSPFPFAELDNVVMTPHFSATADDTYSERAEEVVENLVHLLDGTALRNVVREASP
>NZ_CP040605.1|WP_168587895.1|5340202_5341198_+|sugar-kinase
MTTADELDLVAVGETMVMVTPEPGGRLDTRSSFILRPGGAESNVAALLAKLGHRSAWASAVGTDPLGDIIMEFLNGQGVDVDLVRRDERRPTAVYFKDPAPSGTKVYYYRTGSAASAMNTSDVAAWTRRPARIVHISGITAAISADGMDVARHVVSDRPFGPALVSFDVNHRPNLWTNGAAELRALAQRSDIVFVGRDEAEALWGTSDVDSVRDLLDEPTSLIVKDGATEAVAFTPAGVFREPSIRTDVVDAVGAGDAFAAGWLSGLLDDRDEVTRLRLGHYVASRVLASPSDFAELLPAREIVGMLDSLFDEPNGEAADDPRSDDLCRRP
>NZ_CP040605.1|WP_168587896.1|5341182_5341938_+|IclR-family-transcriptional-regulator
MSQTVARAIDIIGFVSRQHRSLGEIAEHLGVHKSTALRLLQTLEEGGFVRRVSEGYGMGFQLIALGQLALDQVEARSLAHPVLQELSEQYGHTVHLGELVGHQIVYVDKIDGRGSVAMGSRIGLPALVHTAGVAKIITAYQVHDTRARILDGATFERYTPTTITDRADLEKDLDATRDRGWAEDNGEREDYINCIALPVFDARGKVTHGISITALRAVAPLEELRGHIDRFRAAAHRISKSLGWRGDQYGH
>NZ_CP040605.1|WP_168587897.1|5341927_5342542_+|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase
MDTDTFFKRRLDRNPVLGIFRNLSPGQTVAMCERAWDFGVELVEVPVQSPDALPALRAALAAAKPRGKPIGAGTVTAVDQLAAVHDLGVEFTVAPGTHPDVIAESRRRGLPHLPGVATATEISTALAGGLIWLKAFPAAQLGPDWISAQLAPFPDIRFVATGGVDASNAARFLAAGCRGVAVGSALSDPDALPELRRALAKTER
>NZ_CP040605.1|WP_168587898.1|5342717_5344085_+|MHS-family-MFS-transporter
MTPSPTSAAALDSRGTRRVVIASSIGTVIEWYDFALYGAASALVFGPLFFPEQSAIGGALASFAVFAVAFFVRPIGGMIAAHIGDRIGRKPILIFTVTLMGAATVAVGLLPTYEAIGMWAPILLVLTRMLQGIGAGAEFAGAVTAVAEYAPQNKRAFYTSFAQASVGLAFVLSTGFFAVLAAIPRDALLNGAWRIPFLASVVIFGVAIFIRRRVEETPEFTQARSEISKATTEPTKIPLLQAIKASPRELIVGILCGSGLNVAGYLVNTFSLSYIKTTLEMSATVATLGVVAATGSSVIAVPLFGIFADRIGRWPVLLGGAIFTAIYMPFYFMLLDTRQPGIVVAAMVIAYGVGQSAMLGSQSAFLSELFETRYRFTAIAASREINVMVLGGTTPFIATALVGATNGSPWPVVLFVVASQFLTIVSVLLARRARRIPGTGPSNSPARETESQPLT

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Crispr_ID: NZ_CP040605_18

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_18

5642231-5642333

Orphan

Consensus_repeat	Method
GCGCTTGGTTCGGAGTTGCGGACGGCGGTCAACGACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040605_18

>merge|NZ_CP040605|18|5642231-5642333|CRISPRCasFinder
GCGCTTGGTTCGGAGTTGCGGACGGCGGTCAACGACTTCCACCGTGATCGCGGCAGGCAGGTGGAGGCGCGTGGTTCGGAGTTGCGGACGGCGGTCAACGACT

>NZ_CP040605|18|17|5642231-5642333|CRISPRCasFinder
GCGCTTGGTTCGGAGTTGCGGACGGCGGTCAACGACT	TCCACCGTGATCGCGGCAGGCAGGTGGAG
GCGCGTGGTTCGGAGTTGCGGACGGCGGTCAACGACT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168588071.1\|5624062_5624701_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373064
NZ_CP040605.1\|WP_168588081.1\|5655502_5656759_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168588079.1\|5644404_5651397_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274009
NZ_CP040605.1\|WP_168588077.1\|5630095_5633440_+\|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|239160
NZ_CP040605.1\|WP_168590367.1\|5633708_5634983_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379730
NZ_CP040605.1\|WP_168588072.1\|5625628_5625796_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168588076.1\|5628582_5629956_+\|phenylacetate--CoA-ligase-family-protein	unknown	unknown	gnl\|CDD\|274074
NZ_CP040605.1\|WP_168588083.1\|5669058_5670090_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168588080.1\|5651798_5655542_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274009
NZ_CP040605.1\|WP_168588074.1\|5626231_5626444_-\|winged-helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379282
NZ_CP040605.1\|WP_168590368.1\|5672391_5674242_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NZ_CP040605.1\|WP_168588075.1\|5627911_5628577_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|188483
NZ_CP040605.1\|WP_168588082.1\|5658834_5668980_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274009
NZ_CP040605.1\|WP_168588084.1\|5670686_5671520_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|252734
NZ_CP040605.1\|WP_168588085.1\|5674530_5675889_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|365860
NZ_CP040605.1\|WP_168588070.1\|5621847_5622444_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168584616.1\|5622528_5623365_+\|transposase-family-protein	unknown	unknown	gnl\|CDD\|372577
NZ_CP040605.1\|WP_168588087.1\|5678240_5678414_-\|DUF397-domain-containing-protein	unknown	unknown	gnl\|CDD\|377231
NZ_CP040605.1\|WP_168588073.1\|5625782_5626289_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|315923
NZ_CP040605.1\|WP_168588086.1\|5675899_5677939_+\|NADH:flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240085

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168588071.1\|5624062_5624701_+\|hypothetical-protein	gnl\|CDD\|373064	pfam14430, Imm1, Immunity protein Imm1. A predicted immunity protein, with an alpha+beta fold and a conserved C-terminal tryptophan residue. The protein is present in a wide range of bacteria in polymorphic toxin systems as an immediate gene neighbor of the toxin gene.	6.48968e-05
NZ_CP040605.1\|WP_168588079.1\|5644404_5651397_+\|hypothetical-protein	gnl\|CDD\|274009	TIGR02169, chromosome_segregation_protein_related_ptotein, chromosome segregation protein SMC, primarily archaeal type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	3.20901e-10
NZ_CP040605.1\|WP_168588077.1\|5630095_5633440_+\|molybdopterin-dependent-oxidoreductase	gnl\|CDD\|239160	cd02759, MopB_Acetylene-hydratase, The MopB_Acetylene-hydratase CD contains acetylene hydratase (Ahy) and other related proteins. The acetylene hydratase of Pelobacter acetylenicus is a tungsten iron-sulfur protein involved in the fermentation of acetylene to ethanol and acetate. Members of this CD belong to the molybdopterin_binding (MopB) superfamily of proteins.	1.64659e-91
NZ_CP040605.1\|WP_168590367.1\|5633708_5634983_+\|hypothetical-protein	gnl\|CDD\|379730	pfam15567, Imm35, Immunity protein 35. A predicted immunity protein with an alpha+beta fold and a conserved tryptophan residue. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, usually containing a protease domain such as Tox-PL1 and Ntox40. In some instances, it is also fused to a papain-like toxin, ADP-ribosyl glycohydrolase and a S8-like peptidase. Based on these associations the domain is likely to be a protease inhibitor.	8.58851e-19
NZ_CP040605.1\|WP_168588076.1\|5628582_5629956_+\|phenylacetate--CoA-ligase-family-protein	gnl\|CDD\|274074	TIGR02304, conserved_hypothetical_protein, putative adenylate-forming enzyme. Members of this family form a distinct clade within a larger family of proteins that also includes coenzyme F390 synthetase, an enzyme known in Methanobacterium thermoautotrophicum and a few other methanogenic archaea. That enzyme adenylates coenzyme F420 to F390, a reversible process, during oxygen stress. Other informative homologies include domains of the non-ribosomal peptide synthetases involved in activation by adenylation. The family defined by this model is likely to be of an adenylate-forming enzyme related to but distinct from coenzyme F390 synthetase.	2.58311e-30
NZ_CP040605.1\|WP_168588080.1\|5651798_5655542_+\|hypothetical-protein	gnl\|CDD\|274009	TIGR02169, chromosome_segregation_protein_related_ptotein, chromosome segregation protein SMC, primarily archaeal type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	9.06884e-10
NZ_CP040605.1\|WP_168588074.1\|5626231_5626444_-\|winged-helix-turn-helix-domain-containing-protein	gnl\|CDD\|379282	pfam13592, HTH_33, Winged helix-turn helix. This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.	4.79709e-13
NZ_CP040605.1\|WP_168590368.1\|5672391_5674242_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	3.43658e-35
NZ_CP040605.1\|WP_168588075.1\|5627911_5628577_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	3.59278e-19
NZ_CP040605.1\|WP_168588082.1\|5658834_5668980_+\|hypothetical-protein	gnl\|CDD\|274009	TIGR02169, chromosome_segregation_protein_related_ptotein, chromosome segregation protein SMC, primarily archaeal type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	2.34826e-14
NZ_CP040605.1\|WP_168588084.1\|5670686_5671520_-\|hypothetical-protein	gnl\|CDD\|252734	pfam04672, Methyltransf_19, S-adenosyl methyltransferase. This family contains a SAM (S-adenosyl methyltransferase) domain, with a central beta sheet with 3 alpha-helices on both sides. Crystal packing analysis of the structure Structure 3giw suggests that a monomer is the solution state oligomeric form. An unidentified ligand (UNL, cyan) was found at the putative active site surrounded by the residues His57, His170, Phe171, Tyr216 and Met22. The UNL is likely to be a phenylalanine or phenylalanine-like molecule. (details derived from TOPSAN).	9.6299e-95
NZ_CP040605.1\|WP_168588085.1\|5674530_5675889_+\|MFS-transporter	gnl\|CDD\|365860	pfam00083, Sugar_tr, Sugar (and other) transporter.	1.20054e-43
NZ_CP040605.1\|WP_168584616.1\|5622528_5623365_+\|transposase-family-protein	gnl\|CDD\|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.95997e-24
NZ_CP040605.1\|WP_168588087.1\|5678240_5678414_-\|DUF397-domain-containing-protein	gnl\|CDD\|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.31648e-15
NZ_CP040605.1\|WP_168588073.1\|5625782_5626289_-\|hypothetical-protein	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.93763e-18
NZ_CP040605.1\|WP_168588086.1\|5675899_5677939_+\|NADH:flavin-oxidoreductase	gnl\|CDD\|240085	cd04734, OYE_like_3_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 3. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase. One member of this subgroup, the Sinorhizobium meliloti stachydrine utilization protein stcD, has been idenified as a putative N-methylproline demethylase.	9.56665e-168

>NZ_CP040605.1|WP_168590367.1|5633708_5634983_+|hypothetical-protein
MNELAERARTWLHDTYGQRVVLRDEEAILSTERVAFFGCRYVESDEPMLAATICVPRDGADPFPASNAGPLDEALNVSRSEPRAWRWRVNARNCVIATDAAVNCWPASALPWDPAGETPGWWDRMLAAYFPDAEVLICSTWADASRAIVDGGVGTRAVVWLRRQLGGRELAGHLLYADYADDAVVFLDGLRGTVAEQNDAEVAELVVARFRRRQDESVGGLLPSEAAADEFAGAVEKAQAWLAYRYDGEVELVGPDPADETERGWLFACTTRSFQRSGDWRDQMLDAAVVVPKAAGEQPFGLPNRDPWTWLDDWNAGKPGLMPPPEPAQAAWFGPMVAELGPVVGSSVHEHWFGVLEEIASFPARTQALVWLRRRDPRGRESVGHLLVAVNETEGVQLFDPMDGRAQPLIETVPFEFRVMRFDS
>NZ_CP040605.1|WP_168588077.1|5630095_5633440_+|molybdopterin-dependent-oxidoreductase
MSEEVRGFCTLCRSRCGAVYTVDAGALTSVRPDPEHPTGAALCPKGRAAPEIVRSPRRLTQPLRRTRPKTEPDPGWQAIGWDEAMREIAEQLARIRDASGPEAVAFAVTSPSATPMSDSIDWVERFIRLFGSPNICYATEICNWHKDFAHAFTFGCALPTPDYAGADLAVLWGHNPAKSWLAQSAALAEARARGTSVAVVDPRRSTSALQADHWLRVLPGTDAALALGLANELIRTKAYDEGFVREWSNGPLLVRTDNGRFLRAEELDPELDGFVVWDEEIGSAVTYDTQRAAAHPERFALLGRRRVATRHGDVECVPAFERYAAACAAWPLERTSATTGVEVRALHEFARDLANAGSVAYYGWTGVGQHANATQTDRAIATLYSLTGSFDAPGGNVVLPKLPVNQVTTPGQLTAEQREKALGASEFPLGPPTQGWVSARALCESVLSGQPYRVRALVGFGSNLLVSQPNPGRTAEALRSLEFQVHLDLFANPTADFADIVLPVNSPWEREAIRAGFDITQRAQEHVQLRPRLVEPVGQSRSDTDVVFDLAQRLGMGEQFFDGDITAAWNHQLAPLGVTVDELRRRPGGMQIPLDTRYRKYADVGDDGQVLGFGTPTRRVEMYSEQLADHGYSPVPEHVTPPGTDTAPLVLTCAKNGYFCHSQHRGISSLRKRSPEPVVDISPQAAAERVISDGQWVSIVTDNGTVRMRARIDPALHPRVVVAEYGWWQDAPDLGLPGSDPLQQGGHNYNLLISDDVHDPISGSIPMRSFGCDVRPEPTAAWPGLRSFTVADIAAETDGVRALRLRPSDGGVLPDFRPGQHITLNHLDTTRSYSLIGAARVDERDAYTVAVRHVPDGDFSTFVHERLRPGAEVSVAAPAGSFVIPAEIDLPVVLLAAGIGITPFLSYLETLAATGGTVPKVVLHFGNRNQHSHPFGDRIRELQRAIPQLTVIDHYSRPAGEGSAFRSGRLHAGQVDAELIRQRARFYLCGPEEMLRDLSTGLVARGVPRFEIFAEKFHAAAREVAIPDDAAAEVHFARTGKTLRWRKADGPLLQFAEDGGIPLPSGCRLGQCESCAVTVLNGRVAHLVAPTDDLSEDACLTCQAVPVSDLTLDA
>NZ_CP040605.1|WP_168588076.1|5628582_5629956_+|phenylacetate--CoA-ligase-family-protein
MGDSVRELARDARQAVREGPVGIARHQRAHLTDLVAHARANSPYYRELYRDLPDGVDDPTVLPVTSKKELMARFDDWVTDREVTREKAEAFVADPDAVGKRFLDKYLVATTSGTSGLRGLFLLDERSMNMEGALGTRASGVLGAGDAIRMLARGGRTAIVTAPGGHFFTVAGTARFQRDHPRLGRRLRVFSIHRPLPELVEELNRFNPAVLSGFLGMLTLLAGEQEAGRLRIRPALIIPGGETLTTGLGKRLATAFGAKVRAAYAATECSFLSMGCAHGWYHVSSDWAVLEPVDADYRPTPPGELSHTVLLSNLANRVQPFLRYDLGDSILLRPDPCPCGSVFPAIQVQGRAADLLTFPAEDGEPVTMSPMLFGTVLDRVTGIGQYQVVQTASSTLRVRLRPADSAAAEQVWQTVRGEITHLLKEHEVADVTLERADEAPQQEPGGKFRRIIPQTKP
>NZ_CP040605.1|WP_168588075.1|5627911_5628577_+|TetR-family-transcriptional-regulator
MYVRGVEESRRERKKRLTRQRIVLAAIRLFDKQGYEETTVTQVAEAADVDPKTFFNYFRTKDEVLFNELDLEFDVLLAAIRDRRSEESPGEVLRRAVQEYAAHRRPNVPRREPAEVSAAARLALTTPALQAKGAYLLLDLQQRIAAELLNAFPGELDPVTAAAMTGSVLGAIQQASLASAKLGRSQQELWEAAEHALDIATNGLLSVRPRTRDQKQTEERI
>NZ_CP040605.1|WP_168588074.1|5626231_5626444_-|winged-helix-turn-helix-domain-containing-protein
MWTRKAVAELIRVRHGVVLSLRTVGDSLRCWGVSPQRPIRRAYERDPEAVCWWLEEAIRPSPPAPAARAR
>NZ_CP040605.1|WP_168588073.1|5625782_5626289_-|hypothetical-protein
MAGGGYPAIAARARREGAVILWLDQTGIRSDAAVGRTWAPAARTPVVGKTGETVQRDHLDRQVQVIVDGHPVHRRKTVRKWVDDHAAAIEMHFLPGYNPELNPDEIRGADLKRTMSTGTAQKIRDESKQAVRSFLHRLHKSPDQVRSYLGKPDVRYARLTSHNCPTNQ
>NZ_CP040605.1|WP_168588072.1|5625628_5625796_+|hypothetical-protein
MEEQELLVISVRQRSVVQDRLNLVHGDPSKSGGGDGHGEQGGDGLNIPEWPVIDS
>NZ_CP040605.1|WP_168588071.1|5624062_5624701_+|hypothetical-protein
MTVHGTTTTAGRSPRSTGGKHERFWADVLNDQEVLLTPTMDIEEIIRGLAEHDQECQRPEAGLAWFLLHEPDEDAPTLTLGVRGTIGSLMWFDATSALVPADGTNAGYVGYFTMDGHMMVMSPHAELPIARVHEALREFARTQQLPSPCCFGTGWQVSTVLPRGDVAVRAGFSELAGVGGYHFVGGTPSEATVGHGGGDQEFGQVVADGRRR
>NZ_CP040605.1|WP_168584616.1|5622528_5623365_+|transposase-family-protein
MVTYSAKLDVPRELVVFLSRLLAGERRRKGTRKGRRALTTFWQAVLVLRWFRDDTDITKLARDHGVARATGYRYVDEGIKALAAQAPDLHDALQRAKDNGDAYLILDGKNFSSDRLGEKTTSAKGAEIDLWYSGKTREQAGNIQALTDPDGFPLWASDVEPGSIHDITAAENHVLGALYWAYSQLNLPTLADGGYQGAGAGVLTPIKRPKTSKGRPLDVDNQTYNKLLRGLRALGERGFALLTGRWRVLRHFTTSPRKIGLIVKAALVLTQFEHGRLA
>NZ_CP040605.1|WP_168588070.1|5621847_5622444_+|hypothetical-protein
MSSLGEVVSCLYLFLGKCDHAQTWLTKAQELAEEAHELTAHALTGSVASDVVDGLGALAAAPFTVADAAKIIWKTQSTVQGYLASIGAGFTSSATSAAVPTPPEPGTWLRRTAAVHAEETGRDIGRRPNSRSTRNHVREVASREELDALFTALSVSGKELDKPAYPGRMVKLPDDTNIEVISVRSLWRAACRNGCVIG
>NZ_CP040605.1|WP_168588079.1|5644404_5651397_+|hypothetical-protein
MFETPEAFAARVLRDERFVPGVPVAFLACGALRQPPGGGDSFAKLFEDASGVEWMWATEADVWQTADGLIHATETVVTQDGRIFPVFDNNKGTGQWSLRNRGTEVGALGSELRTAVNDFHRDRGRQVEARGSELRTAVNDSAVPRHPEGAHSAPVFKWAGTPGPSGTSRTAGNEERNERKRTRWARDKEKQAALVADGRALLEKLTTRQAELKALPELDAEQAEEWNALPGRIAEVQANVAAVEQKEADRKAKNAAAEKRRYERTKRGTNELVEGGTVLLEELMVQRAPLAVLAELTVLDTDQRAELEELDASIEEVRNELATIANEEQDRKARHAESMKKQRDRKKRGQADALASLAAARAGRAKLEELPGFKEVLQLDPDMLPEFYKEPRRQWEALQREEAAALEVLHEHERMHNQVNAQMRKFKDRYKDEWAQESKSLRELMARQAKLEVLTARDETETRGEELAELEGLPGRIAEVQAKLPAIAKLEAERKAKNAEKEEKRRARKKANTLLATFRTRREELVESGAGQVTELEKVQGSIAALEAELAAIENDDMGSGATARGNGGADREPPAGVVELVGLVGRVEGHLSVLPKNFRPDVHEQVEQAWAMAKKGSWTRADPARIDSKLGRMRDLERWLSEVVRSPGVVELEGLVGRLEGHLSMVPADVLLDVRAGVVKAKAMARQGSWTPKDRAWIDSKLAGMRKGEQWLAEVVSSPGVVEFVGLVERLEGHLSVLSAGFRPDVRAGVAQAKAMAQKGNWTPEELSLIASNLGRMRKLERWLRLEPVVFGVHPDVVKLASGLRGVQVVGVHVTPDGQAQSADDVLETPEDFAERVLRDERFVPGVPVAFLACGALRQPPGGKDSFAKRFEDASGVELMLATEADVWQTADGLIHATETVVTQDGRIFPVFDNNKGTGYWSLREGGREVGALGSELRAAVNDFHRDRGRQVEVRGSELRTAVNDSAVPSDSEGAPPAPVFKWAGTPGPSGTSRTAENEERNNRKGTRWARYKEKQAALVADGRALLEKLTTRQAELKKALPGLDEEQVKEWDALPGRIAEVQANVAAVEQKEADRKARNAASEKRRYKRTKREQDELVDARKVLLEQLMVKRAPLAVLAELTVLDTDQRAELEKLDASIEEVRNELATIANEEQDRKEKNAERVRKQRARKKRGQADALASLAAAEAGRAKLKELPGFTEVLQADPATLPEFDREDRRRWEAWQREEAAALEVLHDHERMRKRNRGAARMRKSEDRYKDEWAQESKSLRELMARQAQLETLMARDETWGEELAELAGLPGRIAEVQAKLPAIAKLEAERKAKNAEKEKKSQARRKANTLLATLKAQRAKLVESDSVQGPEWEEVQGSIAALEAELAAIENDDTGSGATARGNGGADREAPAGVVELVGLVGRVEGHLSVLPAGFRPDLHVQVEEAWAMAKKGSWTRADPARIDSQLERMWKIERWLGAVVSSPGVVELEGLVGRAEEHLSMVPADVLLDVRAGVVKAKAMARQGSWTPKDRAWIDSKLAGMRKGERWLAEVVSSPGVVEFVGLVERLEGHLSVLPADFRPDVRAGVVQAKAMAKKGNWTPEELSLIASNLGRMRKLERWLRLEPVVFGVHPDVVKLASGLRGVQVVGVHVTPDGQAQSADDVLETPEDFAARVLSDERFVPGVPVAFLGCGALRQPPGGGDSFAKRFEDASGVKLMLATEADVWHTDDGLIHATETGVTQDGRIFPVFDNNKGTGYWSLREGGREVGALGSELRAAVNDFHRDRGRQVEARGSELRTAVNDSAVPRHPEGAPPAPVFKWAGSPGPSGTSRTAGNEERNARDRKRRARKKAEEAALVADGRALLEKLTTRQAELKALPGLDEEQAEEWNALPGRIAEVQANVAAVEQKEADQKARNLASQKRRYKRTKREQDELVDARKELLEQLMVQRAPLAELAELTVLDTNQRAELEELDASIEEVRNELATIANEEKDRKEKNAENMRRYRDRKNRGLADARASLAAARAGRAKLEELPGFTEVLQLDPDTLPEFYKEPRRQWEALQREEAAALELLHEHERMRNQGVARMRKFEDRYKDEWAQESKSLRELMARQAQLETLMARNETRGRSWRSWRGCRGVSRRCKRSCPRLRNWRRSGRQRMRKTTRRIGPARRRIRRWRRSRLSGRSWWSRLTFTGQSGRRCRGVSRPWRRSWPRLRTTIRAAAQRPGETGVRIGRRRLGLLSWWGWLGVWRGICRCCRRVSVRICMATLRKRGRWRRRGAGPRRIGPGLIRSWRGCGSSSGGWVRLSGRLGLLSWRGWSGVRRNICRWCRRMSFWMCVPVL
>NZ_CP040605.1|WP_168588080.1|5651798_5655542_+|hypothetical-protein
MTPDGQAQSADDVLETPEDFAARVLSDERFVPGVPVAFLGCGALRQPPGGEDSFAKRFEDASGVKLMLATEADVWHTDDGLIHATETAVTQDGRIFPVFDNNKGTGYWSLRNRGREVGALGSELRTAVNDFHRDRGRQVEARGSELRTAVNDTPVPRHPEGAPPAPVFKWAGTPGPSRSRTAENEEGNARGRTRWARDKEKQAALVADGRALLEQLTTRQAELKALPGLDAEQAEEWNALPGRIAEVQANVAAVEQKEADRKARNLASHKRKYGRTKRETNELVELLEQLMVQRAPLAVLAELTVLDTDQRAELEEWDASIEEVRNELATIANEEQDRKEKNAERMRKQRARKKRGQADARASLAAAEAGRAKLEELPGFTEVLQADPATLPDFYKEPRRQWEALQREEAAALEVLHDHERMRDQVAVRKRKFRDRYKDEWAQESKSLRELMARQAQLETLTARDETRGEELAELAGLPGRIAEVQAKLSAIAKLEAERKANNAEKVKKHRARKKANTSLATLRTQRAKLVESVDVHGEEWEKVQGSIEAVEAELAAIENDDTGSGATARGNGGADREPPAGVVELVGLVGRVEGHLSVLPTGFRPDLHGHVEEAWAMAEQGSWTPEDRAWIDSQLERMRDLERWLGEVVRSPGVVELEGLVGRVEGHLSMVPADVLLDVRAGVVKAKAMARQGSWTPKDRAWIDSKLAGMRKGEQWLAEVVSSPGVVEFVGLVERLEGHLSVLSAGFRPDVRAGVVQAKAMAKKGNWTPEELSLIASNLGRMRKLERWLRLEPVVFGVHPDVVKLASGLRGVQVVGVHVTPDDGQAELAAGVSETPEDFAERVLGDERFVPGVPVAFLGCGALRQPPGGEGSFAKRFEDASGVELMLATEADVWQTADGLIHATETVVTQDGRIFPVFDNNKGTGYWSLRNRGTEVGALGSELRTAVNDFHRYRGRQVDARGSELRTAVNDSAVPRHPEGAPPAPVYKWAGTRGRSRTIRPAKNEERNEKERARRARNKEEEKKEAARVAELEAFVERANSGQASLAASQEPDATEPRQWGELQREVQDAQAELKKIADDRTARRAKRAGYQKSYEERKKRKVADAEELLAAARAGRTKLEELPGFTAVLEANPVRLPESLKKSRSKWEALLEDEAASQEVLQKHERTRNQRNARNTRSNKRYQDEWAQESQSLRELMARQAELEALTARNETRGRSWRSWRSCRGVSRRCKQSCPRLRNWRRSGR
>NZ_CP040605.1|WP_168588081.1|5655502_5656759_+|hypothetical-protein
MPAIAKLEAERKVKNAEIEKKNKARMKANTLLATLMTQRAKLEESGAVPGTEWEKVEGSIAAVEAELAAIENDDMGSGATARGNEGADREAPAGVVELVGLVGRVEGHLSLFPEDFRPDLHDQVEKAWAMAKKGSWTRGDPPRIDSKLAGIRELERWLSEVVRSPGVVELVGLVGRLEGHLSKLPAGFRPDVRAMVAQARAMAQQGSWTPEDRRLAGMRKVERWLAEVVSSPGVVEFVGLVGRLEGHLSKLPAGFRPDVRAGVAQAKAMAQKGNWTPEELLLINSQLERMRERERWLDEVVRSSGVVELGGLVERVEGHLSVLPADVLLDVRAMVVQARAMAQQGSWTPEDRRLAGMRKVERWLAEVVSSPGVVEFVGLVERLEGHLSVLSAGFRPDVRAGVVQARAMAQKGNWTRRS
>NZ_CP040605.1|WP_168588082.1|5658834_5668980_+|hypothetical-protein
MPTPSADDARAETDEDMQSEFDEDYNVRDSDEQRSEVPERFPSSVSGQVLGAGVEEIPAGIMVSPSDLGEDLVAVARALPVEDGVLAVVAKGDGHGGVLLGGKSVDAQRLASLIQGGLRGKRKIRLYACEVSEEFATALDGASGVEVIWTRGLVWFGPDTKGFSSMVGGWYLDEYFTLRPDLTEEVPWVTTRPEAWPPGQSPSDVSLPPGRRGLSPRWVHLRAETARFRTGPQPDLAWLRESGQTAKVVQARSAITAADDRLTQVYSMVDAPVPEEPATTVTAAGSAETDVLVKAATDVTTSAAASVERAARQAGKWTAAQQELTAATQRQGEVRAELKAAAQDLGAAQKDLVQKQAEERVARERVKLLGNEDEDQGVVREKLRAQHAAAAARVKTAEAALTAVQERVDRLARADREAGEHIAVAVARVESERGFTVDAARTATKAVAQARIAADRADVTVRQVDLPSYTGDGAMGSGKIWRPGEIDPEQVLAALPVGVREGARAVVEELFSEAKIGDTLRRLADEGIRVEVDSRELHVKFERTAATPVQVPKGEGFTEWGIRSADASRTITREGGPQYSLPAGIPNMLGAATEGVARSWLLHPSVRPSWGTNEQRNLVSTTEFSRGINSRPAERHSIQVPERHFVVDGRFVIDVRVGEEPPRTYRSDVIRDVALVRFYGEDVPPATINPGPGGPVLPVPASALHEVFVVPQAAAVRRIRQRVLAGLPLPKVGVEVRDAVSRELAEDAAIVKFGEITGGGYRSSPLRLPGATLNTLSLEVSAALRSVRRVDDRVVPDVNLRQIAGGDTKSDTSVAQSASAEASASVGPALVTELKEQRRGLGAYTVITPFTVSGAAESGETLTQVVGTSSGKKTVASIEGDSVLVEATLDMRVQRYSTDPALEGSDTVAEKVFLWMPVEEFARLEEISAAHSALRVAEEHDGPHEPPAVPERLRQSQNFRDLVDRVRPEVTRTPAETETEAVTEAVTEAVTEAVTEAVTEAEAVTEAEAGGGDARLGNDRAEQLALSILADYGKRPEITIPVGGRRQPDMLAAGKSTGGGVVDRAPGIERVLPEVRRLLRESVGEELASLDHDLRSVVESLLSSAFGAPGLFREFSGELRGATETIRVGDRLVTIEVRPRLGALVGTGRVEKANVDVTARNAIRGEGKAKAGTKQRIGVESGATVGTKRKDFWRTLGFLATGSVQFSHSYTGTVGQSHKVHRRARFVGPAVTFDRRVTWSISVSTKTIPAETGQPEPSQTGQPEPQAGQPEPSQAGQQGSQAGQSGSWYRGLGLLGGWGRRSDEADSGGIELDTLSGDTVTAGSDSDSVGSFGGASASSSATTVSGSTVDGWTRVLVPEPLAPITEQGDLRNLGTVIRDFDYDDQDGNPFQVHVEFVMPQGVATPSTVLGEPIEAILEDRAGGQRQDLTTAGENSPDSLEAQFDQLVSPGGVVIAGSRVRLRLFDVHPVGTAAKKLNLEVGTEGGLKLDGQEMRGRGFEGRLRGSAWMLFGGKSSRAYVAPSLTGRGRFGEEEGATFGRGTQRRRVGRTTGATHLYRAHGVFEITSYGESGAAGSTETVVVGGGVEFLLSDIVAQRLRTHPVREPAAQGRPPRTRHLELPAGVEPKPAPVTEVRYPPEFVFSGAALGPTLVTEISNAHEVAPLIKSMISEHAPGFRSGRWLEVPTGIAGSVDTLASVNALAARFGQEATSGVPLLAARPYRGGTETIEFVIRARYAPDAVATPDKDTKSDTSFLHSEKRVHTVARSRAVGGGASVLVAGKGRGNLRRGGAHPQVGYDNESSRIQRDSESDTFKSRVLGTEAISYSYTWPTWFQVEMYRTWTPNAMLNTLLLNKPRQGIEMWAAMREDTRTPLQRGFTSEGTARYIIPGGLTTTTPPLPRPVRIGGRLVPAGGAQRLGPLPQDLRGVDVIPLALPGSERLFPWLAAVLAHPAPEPADDADPQTSEGSMRAPAGNGWVRPATLPAQMLWQLGGEEGLTAMMPDLLADPVVFPAMVETGMVWDDEHGLAVRLRFTGIEYVDSFTATGELTQEQKTEQELVQSEGGKTSAAVIGQATVDSGGPGASGEHGKLTGDMLFPGETSTLDPSVGLSATWSDPRVQKFTGGTTREVTTERRGLYHVYRAAEAVYTITGLTKRRVFSAALPGKTAEVEVTITNGGYFAVESTQAAAKNLPGPPPKPTTPATAPAPAAALGPAALPAVWTPHTGDEHAAGLLPKIRGHLVVGLTASGGTLTVPELAARIEQLPGWARRPIVLVGTDGSFDLADAARLRDTLGVDVIAADHEVWHAADGRVVTGNLSFVRGGAPTWSERAEAILGGEVRSATAGHWHLLSAAGGTRRLPGADLVAALASTGTPAQAGTAPRSDFRWGARSAPVALAIHGATDTADYTTWTRSPYHAAARPEGSKPLLVLGHDDTIIPNTEVTTLRDHTGADVLARVNRGRGPKWMLHRADGSRPRPVDPPTEVTPTPRPQPLLFAGPEDSPATIAQAARSAPHLPADIQPVGVHVTPDGLAVLPDDRKVTPEAFADEVRQHPRFVPGLTIALLGCAANRPPEPGQPTFAQRFARALRTWVWTTTDDVVQTTDKRVHATQVTVAGDGTLLPQFKNGQGTGHWDLLDPEGQPLRTAGPDLAAAVTPDGTAPPRYPEGTHPTPVIRWTGRNGKRSYVKTAEQKEKYSATERQRYAADPSFREKKAQVRRDRTVLLRERDELVLGAEVLLGAAQARLAALPVGDGARQAVLGRIGDLQGVLDDLRKETSAQILRDEEAARASAAQTEEEREQRRKETKTENQRLRRGRLSAAQREKERERAREYDKRYRAGLGDAQREDQQRNNREMTRLKRERDKLIDEAEKLLGEAEARLAEVEARLAALPWSDKTRQEELERARQEELRCIEDLQGVLDDLRKEEIPVIRRKEAELWAIEEDSGSSDVASVGGRVAASVPDAAQMTESGAREKAASDEQARASLADWVAQVRASLKGIKSRQDWFALQDRDFVLQWGQELPTLDEAMRDEREELQRQLDEITGDVVVELKRLVGLLDGHLAALPADSLPKVRAQFALAKAAAEQGSWPLEQVYKIASKLGGMLEMEQSLRNYRLGLARDGDSRRAIDEGGARTAQDGSRPWPVDPPIEVTHPPRPQPLLFAGPGDSAETIAQAERSAPDLPGTQPVGVHVTPDGLAVLPDGRKVTPEAFADEVRQDPRFVPGLTIALLGCAANRELEPGELTFAQRFARALRTWVWTTTDDVVQTKDKRVHATQVTVTGDGTLLPRFENGLGTGHWDLLGSEGESLWTAGPDLGAAVTLGGSAPPRYPDGTHPTPVIRWTGRPKLTDEQRQRKTANQRLRRGRLSDAPSAQPDDTAPDAMDRNP
>NZ_CP040605.1|WP_168588083.1|5669058_5670090_+|hypothetical-protein
MTTPDQKADVRAALHEVLLRQAGFAPDELVTQARAWLADDRFDEVARAVVSTVARYVLPLTVEDLDVLVTVSEAEGVSLDVLESIEPTIDDPPLVWRFSAQPPDSVDSTDDSAVAALIDVLGEEPAAHGMWRAWRMVPDGAPYPPPRPVYVVEADDDDLPALTARLQEALVAAGEAAPQVEVTPAVGPVPTYQQAARAYGALLWAATEAPEITVARVFDAVDPISGPSFAPDHPRMDNEAERGQILDYLRAGTALMITTATLEDVVDPTRGAVVPMSFRTDGTWIWPDTIAYYLEHHHLAPDPDLLAHIRDAGLLPPELDTVAIHRAMDVLRRPPETEPVWTR
>NZ_CP040605.1|WP_168588084.1|5670686_5671520_-|hypothetical-protein
MKRPSWAPLDVDMNQPSIARIWDWFLGGAHNFAVDRQVAEEMLQLMPEGPQMAHINRMFLRRVVQLCVAEGVTQFLDIGSGIPTVGNVHETAQQADPECRVVYVDIDPVAVAHTRRLLADNPRCAVIQADLREPEEILAAPELRDLLDLDRPVALLMIAVLHFVHDEEDPLGLIARYRDALAGGSFFAIAHGSRSTERMPSEHLYAARSKYERSVAQVSLRSQPEVEAMFAGFDLVSPSVVWLPVWRPANGETPEDSAAPNAGYGGVGRKPRTNRPQ
>NZ_CP040605.1|WP_168590368.1|5672391_5674242_-|GntR-family-transcriptional-regulator
MVGRPRNAVVLTDTERAALLKWTRSRTCSRALALRAQIVLCCEHERTNTAVAQSLGISRGVVGKWRSRFLDQRLDGLHEQPRPGRPRAVDDDAVATVLIRTLAPAPGARHAWSTRSMAAETGLSQTTVNRIWRAHRIHPAAGSSPRRADQASLLPAEIHDVVGLFLDPPVRVLAVSATPHRTPLRDRRPAGRGADRRSAETRNLFAVANAFASLRGMTAGMSGEGVPLRAFLGHLDRTVAASMNVHLLAGGLDEPALRTVDEWLHSQPRFRCHSAPDQSSWIDEIDFLLANNPLPGHENLFGFAASLTKVRNDVRAWCRTWTPRTSPYSWAKSPRALWSGDAANRRLNNDSKSASETTPEQPGRDLEPTSAIPDDPATASGTTDRVVHLVREALAAGQYHAGERVKEAPLAARLGVSRGPIREALRILAEEGTLERLPNRGAAVPDVSATNILDLYAVRASLGALVMRRVAVLGQAHLQPVNTALAEVRAAARNSDDVRIGEADLCFQDAIARTANLPQASSFFERLTMRLRMFISVLRLGYAEAGDLIARENAAIFDALRNGDGNEAARLWRVKVERSVRYMVAQLPRDHFDPDLWITIAGKPNPRPSDPRNLPR
>NZ_CP040605.1|WP_168588085.1|5674530_5675889_+|MFS-transporter
MSSSIIDDQPYGRFHRKLFFLSAGGPFLDGYILSVIGVAITGATRELGLTSFAEGLVGAAALVGVLLGGFVFGWVTDRVGRQVMYTIDLIALVAASALSLFVTEAWQLVLLRFVAGVAVGADYPIATSLLAEWLPAHRRGRTMGALVAAWFVGASASYAVGYLVAAAGGEDLWRWVLASAAVPGLIILLARIGTPESPRWLLRHDRPQDAAEAIRTALGRYPTEQELARLAETEPAKSSRLSDVFTGGYLRRTLFVGGFWLCQVAPAFAIWTFYPVILGAYGFEAGDTALLWSMVVSLVTLAGCVPCIRWVETYGRRPVIIWTFVGVTVSLAALGSFPGMAAALAILMFVVNALAQGGGNILQWIYPTELFPTDIRASAVGVASAISRIGAAAGTYLLPVGLEAIGLGPTMLVGAGLSVIGTAMCVAWAPETKGQALHESAAVPQQSEARAG
>NZ_CP040605.1|WP_168588086.1|5675899_5677939_+|NADH:flavin-oxidoreductase
MSVTRDPLLTPFRIKNLVLRNRIVSTSHEPGYGEDGMPTERYRAYHVEKARGGVGLTMIGGSSVVSVDSPPSFGNLHLYSDEIVPWLRQLSDEVHAEGAAVMCQITHLGHRTSNYTESWLPTVSVGNLREPAHRAFTKQAEIADLERIAADYAAAAARCEAGGLDGIEIQAYGHLLDSFWSPALNNRTDDFGGSFDNRMRFPLQVIAAIRAAVSDEFVVGIRMAVDEQLPGGVDEDEGLAIAAVVVDAGIDFISVIRGHIATESGLSDVIPPMGEASAPHLDLAARVKRKIDVPIMHAAKIADVATARHAIDEGLLDLVGMTRALMADPHLVAKIEAGQEERIRPCVGASLCIDAAYIGEPAYCIHNPSTGRELRLPHRISAAPQAKNAVVVGAGPAGLEAARVLAERGHHVTVFEAAPEPGGQLRLASRVQRRRDLIGIVDWRVAECTRAGVRFKFNHLVEADELRGLAPEVMIIATGGVPNTDFLDFGADLVHDTWDIISGAVLPTGSVLVYDDHGGHPGLDVVELLAGSVAQVEWASPERTVAVDVGSVNAPPYLRTMLNHDVRISLMHRLVGVQRDGDALLATFTSDPTRRSFTRRFDHVVVEHGTLPNAELYEQLKPHSTNEGEIDYAKLLDRSPQDRLRNEDGRFQLFRIGDAVSSRSVHAAVLDAFRLCSAV
>NZ_CP040605.1|WP_168588087.1|5678240_5678414_-|DUF397-domain-containing-protein
MLTQQWIKSSYSSANGDCVELTTTLDAIRDSKDPHGPTLSVDVSTFVRAVQQGRFDR

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Crispr_ID: NZ_CP040605_19

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_19

5644723-5644825

Orphan

Consensus_repeat	Method
GCGCTTGGTTCGGAGTTGCGGACGGCGGTCAACGACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040605_19

>merge|NZ_CP040605|19|5644723-5644825|CRISPRCasFinder
GCGCTTGGTTCGGAGTTGCGGACGGCGGTCAACGACTTCCACCGTGATCGCGGCAGGCAGGTGGAGGCGCGTGGTTCGGAGTTGCGGACGGCGGTCAACGACT

>NZ_CP040605|19|18|5644723-5644825|CRISPRCasFinder
GCGCTTGGTTCGGAGTTGCGGACGGCGGTCAACGACT	TCCACCGTGATCGCGGCAGGCAGGTGGAG
GCGCGTGGTTCGGAGTTGCGGACGGCGGTCAACGACT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168588071.1\|5624062_5624701_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373064
NZ_CP040605.1\|WP_168588081.1\|5655502_5656759_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168588077.1\|5630095_5633440_+\|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|239160
NZ_CP040605.1\|WP_168590367.1\|5633708_5634983_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379730
NZ_CP040605.1\|WP_168588072.1\|5625628_5625796_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168588076.1\|5628582_5629956_+\|phenylacetate--CoA-ligase-family-protein	unknown	unknown	gnl\|CDD\|274074
NZ_CP040605.1\|WP_168588083.1\|5669058_5670090_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168588075.1\|5627911_5628577_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|188483
NZ_CP040605.1\|WP_168588073.1\|5625782_5626289_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|315923
NZ_CP040605.1\|WP_168588074.1\|5626231_5626444_-\|winged-helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379282
NZ_CP040605.1\|WP_168590368.1\|5672391_5674242_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NZ_CP040605.1\|WP_168588078.1\|5635270_5644372_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223496
NZ_CP040605.1\|WP_168588082.1\|5658834_5668980_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274009
NZ_CP040605.1\|WP_168588084.1\|5670686_5671520_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|252734
NZ_CP040605.1\|WP_168588085.1\|5674530_5675889_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|365860
NZ_CP040605.1\|WP_168584616.1\|5622528_5623365_+\|transposase-family-protein	unknown	unknown	gnl\|CDD\|372577
NZ_CP040605.1\|WP_168588088.1\|5678492_5678666_-\|DUF397-domain-containing-protein	unknown	unknown	gnl\|CDD\|377231
NZ_CP040605.1\|WP_168588087.1\|5678240_5678414_-\|DUF397-domain-containing-protein	unknown	unknown	gnl\|CDD\|377231
NZ_CP040605.1\|WP_168588080.1\|5651798_5655542_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274009
NZ_CP040605.1\|WP_168588086.1\|5675899_5677939_+\|NADH:flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240085

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168588071.1\|5624062_5624701_+\|hypothetical-protein	gnl\|CDD\|373064	pfam14430, Imm1, Immunity protein Imm1. A predicted immunity protein, with an alpha+beta fold and a conserved C-terminal tryptophan residue. The protein is present in a wide range of bacteria in polymorphic toxin systems as an immediate gene neighbor of the toxin gene.	6.48968e-05
NZ_CP040605.1\|WP_168588077.1\|5630095_5633440_+\|molybdopterin-dependent-oxidoreductase	gnl\|CDD\|239160	cd02759, MopB_Acetylene-hydratase, The MopB_Acetylene-hydratase CD contains acetylene hydratase (Ahy) and other related proteins. The acetylene hydratase of Pelobacter acetylenicus is a tungsten iron-sulfur protein involved in the fermentation of acetylene to ethanol and acetate. Members of this CD belong to the molybdopterin_binding (MopB) superfamily of proteins.	1.64659e-91
NZ_CP040605.1\|WP_168590367.1\|5633708_5634983_+\|hypothetical-protein	gnl\|CDD\|379730	pfam15567, Imm35, Immunity protein 35. A predicted immunity protein with an alpha+beta fold and a conserved tryptophan residue. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, usually containing a protease domain such as Tox-PL1 and Ntox40. In some instances, it is also fused to a papain-like toxin, ADP-ribosyl glycohydrolase and a S8-like peptidase. Based on these associations the domain is likely to be a protease inhibitor.	8.58851e-19
NZ_CP040605.1\|WP_168588076.1\|5628582_5629956_+\|phenylacetate--CoA-ligase-family-protein	gnl\|CDD\|274074	TIGR02304, conserved_hypothetical_protein, putative adenylate-forming enzyme. Members of this family form a distinct clade within a larger family of proteins that also includes coenzyme F390 synthetase, an enzyme known in Methanobacterium thermoautotrophicum and a few other methanogenic archaea. That enzyme adenylates coenzyme F420 to F390, a reversible process, during oxygen stress. Other informative homologies include domains of the non-ribosomal peptide synthetases involved in activation by adenylation. The family defined by this model is likely to be of an adenylate-forming enzyme related to but distinct from coenzyme F390 synthetase.	2.58311e-30
NZ_CP040605.1\|WP_168588075.1\|5627911_5628577_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	3.59278e-19
NZ_CP040605.1\|WP_168588073.1\|5625782_5626289_-\|hypothetical-protein	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.93763e-18
NZ_CP040605.1\|WP_168588074.1\|5626231_5626444_-\|winged-helix-turn-helix-domain-containing-protein	gnl\|CDD\|379282	pfam13592, HTH_33, Winged helix-turn helix. This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.	4.79709e-13
NZ_CP040605.1\|WP_168590368.1\|5672391_5674242_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	3.43658e-35
NZ_CP040605.1\|WP_168588078.1\|5635270_5644372_+\|hypothetical-protein	gnl\|CDD\|223496	COG0419, SbcC, ATPase involved in DNA repair [DNA replication, recombination, and repair].	2.7316e-13
NZ_CP040605.1\|WP_168588082.1\|5658834_5668980_+\|hypothetical-protein	gnl\|CDD\|274009	TIGR02169, chromosome_segregation_protein_related_ptotein, chromosome segregation protein SMC, primarily archaeal type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	2.34826e-14
NZ_CP040605.1\|WP_168588084.1\|5670686_5671520_-\|hypothetical-protein	gnl\|CDD\|252734	pfam04672, Methyltransf_19, S-adenosyl methyltransferase. This family contains a SAM (S-adenosyl methyltransferase) domain, with a central beta sheet with 3 alpha-helices on both sides. Crystal packing analysis of the structure Structure 3giw suggests that a monomer is the solution state oligomeric form. An unidentified ligand (UNL, cyan) was found at the putative active site surrounded by the residues His57, His170, Phe171, Tyr216 and Met22. The UNL is likely to be a phenylalanine or phenylalanine-like molecule. (details derived from TOPSAN).	9.6299e-95
NZ_CP040605.1\|WP_168588085.1\|5674530_5675889_+\|MFS-transporter	gnl\|CDD\|365860	pfam00083, Sugar_tr, Sugar (and other) transporter.	1.20054e-43
NZ_CP040605.1\|WP_168584616.1\|5622528_5623365_+\|transposase-family-protein	gnl\|CDD\|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.95997e-24
NZ_CP040605.1\|WP_168588088.1\|5678492_5678666_-\|DUF397-domain-containing-protein	gnl\|CDD\|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	5.09896e-16
NZ_CP040605.1\|WP_168588087.1\|5678240_5678414_-\|DUF397-domain-containing-protein	gnl\|CDD\|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.31648e-15
NZ_CP040605.1\|WP_168588080.1\|5651798_5655542_+\|hypothetical-protein	gnl\|CDD\|274009	TIGR02169, chromosome_segregation_protein_related_ptotein, chromosome segregation protein SMC, primarily archaeal type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	9.06884e-10
NZ_CP040605.1\|WP_168588086.1\|5675899_5677939_+\|NADH:flavin-oxidoreductase	gnl\|CDD\|240085	cd04734, OYE_like_3_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 3. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase. One member of this subgroup, the Sinorhizobium meliloti stachydrine utilization protein stcD, has been idenified as a putative N-methylproline demethylase.	9.56665e-168

>NZ_CP040605.1|WP_168588078.1|5635270_5644372_+|hypothetical-protein
MFSSIMVPEGVRRLFQVLTGEDMTDADEGALFAVADVLESGAAGLGEVRALVAELVGKVRTEFSGKAADRFADGLGIFDGLLSSGQAGLLDLAAFVRKTSQQVRYLKLVTIYGLELLAVEMSWAMQFAGATAGATLAWLAARMAVMRFLLTSWWRQLFMRLAMMAAGGVVFNVLPDVQAQLTMRGEESAEKWDRTLTEQAAGMGAFSALVALPMSAVGGLVSNTLTKVLVKGLGDDVDAAILEAAAKKAVAEHAELYPVSAMAKFADAVGKSLDNYAGMSVGAMWLARFGHSVGEALAGSLSEFFGEALYAAATGQKVTWNPFSLTAGFFETVFSGVGNLAGLALRGKLHPEGPSPYLEGTGGGGGGSDDGGGSGGEKTPLPGAGSGSQTGDIPGSPDKDSVFIPSDASDSSDGSRSDRWAGSDSGAGSDSSSVSDVDSVFSDTGSVDSAAVSVPSGDGLVVPGSAVVSAVVVGGTDGKDGTDGTDGKRGADGSVPGRDAAGDVPVVPGSGQHRPGTPPPAYSSGVPGVDPDRPGTPLPAHFGGVPGVGPDRPGTPPPPYSPGPGGDQAVPGKRPLEVSASKTPDSPTVTPHASDVPADAARPETGKPGSVVGPDGRVPAGHPASETVGSGSAADSGSGVSGGHPESPSGVTGRDGDPGADSVAGRGDAHRQDGAVVSPDSATLPGEGSPAAPSLHRDPAAVLPAGLPADTVRVPVPANVVAGDRLGLAEFVRSHGADSPGGPVLLVSPSDPNAGVVVTRGQGLALARDLGRNVVAMMPGQAGREPQFMVFPADRSRPKSLAGPGAAVLAGGRSGGVAGLADASATVPAASGGKTRGEAPAAGTGSAQARSVAGEVQPASTTPGAGAGMVRDTSGIPVGQWTQEELVRAIARARELGLSSDEKDAAAQIVWLAHDVQVLARGDAVVPLEDVVALVAAKYHDLGKDHRDQVVKFSRALADWLGTRRSKPVIHAGAGPEGHTADGGPSGSSSAAVPRNVEGHRRRAETATAKRRTKIAELEDLLKPLRDEQASLEASLGRDEADAGSRTRGEELQGRIARWQAVLDGLKTKDQQVRARGAERTNKWRERQQRKSRAARLGAGGPSPAGRSDQIAGRSEEPSAAAELSELITNANAGLDSMRQQELPVDQLIDAVKPHMESFGGHDGLRDVMAHHMLRYPGDSEETRKFERKLHKLTTVRNWDEWYERDATRLDKWAGIVGRDAVDRLLADADMVLGSLRVSLRFRTVLAQWLGEHPGDRRGAQAVRGIMAGYLAGDPDLGVAVSGLTLDEFETAKAEEARWQEDRAANPAEAAAPMVRGFADDPALDVISRISSIQHKFEDVGQELRQWARTEDQDAVDLLYDQADQVLGPLKESEPFRDVMAHELLMRRNNLRDDQQLQRFMTNPQDDPQLRQLRWELARYLAGDLTGGADPDTADNLLSAGMGPLPEDIRSRGKLMYNRRLTIGKALSGLQDDAVNEVLRNAALEDLRRGKYSHDTLGKRFYRSGPWGGTVFVIRDLQDAVGSLRQVLAEAETNTDRRDEYEPKIAEWLNLRGFLDPTAIRSRATEVADAVRLLRQENANREPTQDGRMLPVFDNGEGTGQWYLRSRDGELEARGSELRTAVNDSAVPTDPEGAPPAPVFRWAGTPGPSRTRTAGNEERKARGRERWHREKAVEAARVAELEAFLKRANSGQDSWAASQESDAANPRQRGDLQREVRDAQAELKKIADDRTAKKAKHAADQKSSEERKRRVVADARASLAAARAGRAELEELPGFDREDRRRWEALQREEAAALEVLHDHELMRDQVAVRKRKLEDRYKDEWAQESKSLRELMARQAKLEVLTARDETETRGEELAELEGLPGRIAEVQAKLPGIAKLEAERKANHAEKEKKNKARRKANTLLATFRTRREELVESDAVQGPEWEEVQGSIAALEAELAAIANDDMGSGATARGNGGADREMPAGVVELVGLVGRVEGHLSVLPAGFRRDLHDQVEEAWAMAKKGSWIRGDPARIDSQLERMRDLERWLGEVVRSPGVVELEGLVGRVEGHLSMVPADVLLDVRAGVVKAKAMARQGSWTPKDRAWIDSKLAGMRKGERWLAEVVSSPGVVEFVGLVERLEGHLSVLPADFRPDVRAGVVQARVMARKGNWTREDLSLIDSELGRMRKLERWLRLEPVVFGVDPGVVKLASGLRGVQVVGVHVTPDGQAQSADDVLETPEDFAARVLSDERFVPGVPVAFLGCGALRQPPGGEDSFAKRFEDASGVKLMLATEADVWHTDDGLIHATETAVTQDGRIFPVFDNNKGTGYWSLRNRGREVGALGSELRTAVNDFHRDRGRQVEARGSELRTAVNDSAVPRHPEGAHSAPVFKWAGTPGPSRTSRTAENEEKKASTTEWRHRKKAEEAALVADGRALLEKLTTRQAELKALPGLDEEQTEEWNALLGRIAEVQANVAAVEQKGADRRARDAASERRRYERTKREKNGLVDARKVLLEQLMVQRAPLAVLAELTVLDTNQRAELEELDASIEEVRNELATIANEEQARKAQHAERMRKQRARKKRGQADALASLAAARAGRAKLKELPGFTEVLQADPATLPEFYKEPRRQWEALQREEAAALELLHEHERMRNQGVARMRKSEDRYKDEWAQESKSLRELMARQAQLETLMARNETRGEELAELAGLPGRIAEVQAKLPAIAKLEAERKANNAENDKKNRARKKANTLLATLKAQRAKLVESDSVQGPEWEEVQGSIAALEAELAAIENDDTGSGATARGNGGADREAPAGVVELVGLVGRVEGHLSVLPAGFRPDLHGHVEEAWAMAKKGSWTPADRARIDSQLAGMRELERWLGAVVRSPGVVELVGLVGRVEGHLSMVPADVLLDVRAGVVKAKAMARQGSWTPEDRAWIDSKLAGMRKGERWLAEVVSSPEVVEFVGLVERLEGHLSVLPADFRPDVRAGVVQAKAMAQKGNWTPEELSLIASNLGRMRKFERWLRLEPVVFGGEMMISGWLRGRWSWPAVCGVCRWWVCM
>NZ_CP040605.1|WP_168590367.1|5633708_5634983_+|hypothetical-protein
MNELAERARTWLHDTYGQRVVLRDEEAILSTERVAFFGCRYVESDEPMLAATICVPRDGADPFPASNAGPLDEALNVSRSEPRAWRWRVNARNCVIATDAAVNCWPASALPWDPAGETPGWWDRMLAAYFPDAEVLICSTWADASRAIVDGGVGTRAVVWLRRQLGGRELAGHLLYADYADDAVVFLDGLRGTVAEQNDAEVAELVVARFRRRQDESVGGLLPSEAAADEFAGAVEKAQAWLAYRYDGEVELVGPDPADETERGWLFACTTRSFQRSGDWRDQMLDAAVVVPKAAGEQPFGLPNRDPWTWLDDWNAGKPGLMPPPEPAQAAWFGPMVAELGPVVGSSVHEHWFGVLEEIASFPARTQALVWLRRRDPRGRESVGHLLVAVNETEGVQLFDPMDGRAQPLIETVPFEFRVMRFDS
>NZ_CP040605.1|WP_168588077.1|5630095_5633440_+|molybdopterin-dependent-oxidoreductase
MSEEVRGFCTLCRSRCGAVYTVDAGALTSVRPDPEHPTGAALCPKGRAAPEIVRSPRRLTQPLRRTRPKTEPDPGWQAIGWDEAMREIAEQLARIRDASGPEAVAFAVTSPSATPMSDSIDWVERFIRLFGSPNICYATEICNWHKDFAHAFTFGCALPTPDYAGADLAVLWGHNPAKSWLAQSAALAEARARGTSVAVVDPRRSTSALQADHWLRVLPGTDAALALGLANELIRTKAYDEGFVREWSNGPLLVRTDNGRFLRAEELDPELDGFVVWDEEIGSAVTYDTQRAAAHPERFALLGRRRVATRHGDVECVPAFERYAAACAAWPLERTSATTGVEVRALHEFARDLANAGSVAYYGWTGVGQHANATQTDRAIATLYSLTGSFDAPGGNVVLPKLPVNQVTTPGQLTAEQREKALGASEFPLGPPTQGWVSARALCESVLSGQPYRVRALVGFGSNLLVSQPNPGRTAEALRSLEFQVHLDLFANPTADFADIVLPVNSPWEREAIRAGFDITQRAQEHVQLRPRLVEPVGQSRSDTDVVFDLAQRLGMGEQFFDGDITAAWNHQLAPLGVTVDELRRRPGGMQIPLDTRYRKYADVGDDGQVLGFGTPTRRVEMYSEQLADHGYSPVPEHVTPPGTDTAPLVLTCAKNGYFCHSQHRGISSLRKRSPEPVVDISPQAAAERVISDGQWVSIVTDNGTVRMRARIDPALHPRVVVAEYGWWQDAPDLGLPGSDPLQQGGHNYNLLISDDVHDPISGSIPMRSFGCDVRPEPTAAWPGLRSFTVADIAAETDGVRALRLRPSDGGVLPDFRPGQHITLNHLDTTRSYSLIGAARVDERDAYTVAVRHVPDGDFSTFVHERLRPGAEVSVAAPAGSFVIPAEIDLPVVLLAAGIGITPFLSYLETLAATGGTVPKVVLHFGNRNQHSHPFGDRIRELQRAIPQLTVIDHYSRPAGEGSAFRSGRLHAGQVDAELIRQRARFYLCGPEEMLRDLSTGLVARGVPRFEIFAEKFHAAAREVAIPDDAAAEVHFARTGKTLRWRKADGPLLQFAEDGGIPLPSGCRLGQCESCAVTVLNGRVAHLVAPTDDLSEDACLTCQAVPVSDLTLDA
>NZ_CP040605.1|WP_168588076.1|5628582_5629956_+|phenylacetate--CoA-ligase-family-protein
MGDSVRELARDARQAVREGPVGIARHQRAHLTDLVAHARANSPYYRELYRDLPDGVDDPTVLPVTSKKELMARFDDWVTDREVTREKAEAFVADPDAVGKRFLDKYLVATTSGTSGLRGLFLLDERSMNMEGALGTRASGVLGAGDAIRMLARGGRTAIVTAPGGHFFTVAGTARFQRDHPRLGRRLRVFSIHRPLPELVEELNRFNPAVLSGFLGMLTLLAGEQEAGRLRIRPALIIPGGETLTTGLGKRLATAFGAKVRAAYAATECSFLSMGCAHGWYHVSSDWAVLEPVDADYRPTPPGELSHTVLLSNLANRVQPFLRYDLGDSILLRPDPCPCGSVFPAIQVQGRAADLLTFPAEDGEPVTMSPMLFGTVLDRVTGIGQYQVVQTASSTLRVRLRPADSAAAEQVWQTVRGEITHLLKEHEVADVTLERADEAPQQEPGGKFRRIIPQTKP
>NZ_CP040605.1|WP_168588075.1|5627911_5628577_+|TetR-family-transcriptional-regulator
MYVRGVEESRRERKKRLTRQRIVLAAIRLFDKQGYEETTVTQVAEAADVDPKTFFNYFRTKDEVLFNELDLEFDVLLAAIRDRRSEESPGEVLRRAVQEYAAHRRPNVPRREPAEVSAAARLALTTPALQAKGAYLLLDLQQRIAAELLNAFPGELDPVTAAAMTGSVLGAIQQASLASAKLGRSQQELWEAAEHALDIATNGLLSVRPRTRDQKQTEERI
>NZ_CP040605.1|WP_168588074.1|5626231_5626444_-|winged-helix-turn-helix-domain-containing-protein
MWTRKAVAELIRVRHGVVLSLRTVGDSLRCWGVSPQRPIRRAYERDPEAVCWWLEEAIRPSPPAPAARAR
>NZ_CP040605.1|WP_168588073.1|5625782_5626289_-|hypothetical-protein
MAGGGYPAIAARARREGAVILWLDQTGIRSDAAVGRTWAPAARTPVVGKTGETVQRDHLDRQVQVIVDGHPVHRRKTVRKWVDDHAAAIEMHFLPGYNPELNPDEIRGADLKRTMSTGTAQKIRDESKQAVRSFLHRLHKSPDQVRSYLGKPDVRYARLTSHNCPTNQ
>NZ_CP040605.1|WP_168588072.1|5625628_5625796_+|hypothetical-protein
MEEQELLVISVRQRSVVQDRLNLVHGDPSKSGGGDGHGEQGGDGLNIPEWPVIDS
>NZ_CP040605.1|WP_168588071.1|5624062_5624701_+|hypothetical-protein
MTVHGTTTTAGRSPRSTGGKHERFWADVLNDQEVLLTPTMDIEEIIRGLAEHDQECQRPEAGLAWFLLHEPDEDAPTLTLGVRGTIGSLMWFDATSALVPADGTNAGYVGYFTMDGHMMVMSPHAELPIARVHEALREFARTQQLPSPCCFGTGWQVSTVLPRGDVAVRAGFSELAGVGGYHFVGGTPSEATVGHGGGDQEFGQVVADGRRR
>NZ_CP040605.1|WP_168584616.1|5622528_5623365_+|transposase-family-protein
MVTYSAKLDVPRELVVFLSRLLAGERRRKGTRKGRRALTTFWQAVLVLRWFRDDTDITKLARDHGVARATGYRYVDEGIKALAAQAPDLHDALQRAKDNGDAYLILDGKNFSSDRLGEKTTSAKGAEIDLWYSGKTREQAGNIQALTDPDGFPLWASDVEPGSIHDITAAENHVLGALYWAYSQLNLPTLADGGYQGAGAGVLTPIKRPKTSKGRPLDVDNQTYNKLLRGLRALGERGFALLTGRWRVLRHFTTSPRKIGLIVKAALVLTQFEHGRLA
>NZ_CP040605.1|WP_168588080.1|5651798_5655542_+|hypothetical-protein
MTPDGQAQSADDVLETPEDFAARVLSDERFVPGVPVAFLGCGALRQPPGGEDSFAKRFEDASGVKLMLATEADVWHTDDGLIHATETAVTQDGRIFPVFDNNKGTGYWSLRNRGREVGALGSELRTAVNDFHRDRGRQVEARGSELRTAVNDTPVPRHPEGAPPAPVFKWAGTPGPSRSRTAENEEGNARGRTRWARDKEKQAALVADGRALLEQLTTRQAELKALPGLDAEQAEEWNALPGRIAEVQANVAAVEQKEADRKARNLASHKRKYGRTKRETNELVELLEQLMVQRAPLAVLAELTVLDTDQRAELEEWDASIEEVRNELATIANEEQDRKEKNAERMRKQRARKKRGQADARASLAAAEAGRAKLEELPGFTEVLQADPATLPDFYKEPRRQWEALQREEAAALEVLHDHERMRDQVAVRKRKFRDRYKDEWAQESKSLRELMARQAQLETLTARDETRGEELAELAGLPGRIAEVQAKLSAIAKLEAERKANNAEKVKKHRARKKANTSLATLRTQRAKLVESVDVHGEEWEKVQGSIEAVEAELAAIENDDTGSGATARGNGGADREPPAGVVELVGLVGRVEGHLSVLPTGFRPDLHGHVEEAWAMAEQGSWTPEDRAWIDSQLERMRDLERWLGEVVRSPGVVELEGLVGRVEGHLSMVPADVLLDVRAGVVKAKAMARQGSWTPKDRAWIDSKLAGMRKGEQWLAEVVSSPGVVEFVGLVERLEGHLSVLSAGFRPDVRAGVVQAKAMAKKGNWTPEELSLIASNLGRMRKLERWLRLEPVVFGVHPDVVKLASGLRGVQVVGVHVTPDDGQAELAAGVSETPEDFAERVLGDERFVPGVPVAFLGCGALRQPPGGEGSFAKRFEDASGVELMLATEADVWQTADGLIHATETVVTQDGRIFPVFDNNKGTGYWSLRNRGTEVGALGSELRTAVNDFHRYRGRQVDARGSELRTAVNDSAVPRHPEGAPPAPVYKWAGTRGRSRTIRPAKNEERNEKERARRARNKEEEKKEAARVAELEAFVERANSGQASLAASQEPDATEPRQWGELQREVQDAQAELKKIADDRTARRAKRAGYQKSYEERKKRKVADAEELLAAARAGRTKLEELPGFTAVLEANPVRLPESLKKSRSKWEALLEDEAASQEVLQKHERTRNQRNARNTRSNKRYQDEWAQESQSLRELMARQAELEALTARNETRGRSWRSWRSCRGVSRRCKQSCPRLRNWRRSGR
>NZ_CP040605.1|WP_168588081.1|5655502_5656759_+|hypothetical-protein
MPAIAKLEAERKVKNAEIEKKNKARMKANTLLATLMTQRAKLEESGAVPGTEWEKVEGSIAAVEAELAAIENDDMGSGATARGNEGADREAPAGVVELVGLVGRVEGHLSLFPEDFRPDLHDQVEKAWAMAKKGSWTRGDPPRIDSKLAGIRELERWLSEVVRSPGVVELVGLVGRLEGHLSKLPAGFRPDVRAMVAQARAMAQQGSWTPEDRRLAGMRKVERWLAEVVSSPGVVEFVGLVGRLEGHLSKLPAGFRPDVRAGVAQAKAMAQKGNWTPEELLLINSQLERMRERERWLDEVVRSSGVVELGGLVERVEGHLSVLPADVLLDVRAMVVQARAMAQQGSWTPEDRRLAGMRKVERWLAEVVSSPGVVEFVGLVERLEGHLSVLSAGFRPDVRAGVVQARAMAQKGNWTRRS
>NZ_CP040605.1|WP_168588082.1|5658834_5668980_+|hypothetical-protein
MPTPSADDARAETDEDMQSEFDEDYNVRDSDEQRSEVPERFPSSVSGQVLGAGVEEIPAGIMVSPSDLGEDLVAVARALPVEDGVLAVVAKGDGHGGVLLGGKSVDAQRLASLIQGGLRGKRKIRLYACEVSEEFATALDGASGVEVIWTRGLVWFGPDTKGFSSMVGGWYLDEYFTLRPDLTEEVPWVTTRPEAWPPGQSPSDVSLPPGRRGLSPRWVHLRAETARFRTGPQPDLAWLRESGQTAKVVQARSAITAADDRLTQVYSMVDAPVPEEPATTVTAAGSAETDVLVKAATDVTTSAAASVERAARQAGKWTAAQQELTAATQRQGEVRAELKAAAQDLGAAQKDLVQKQAEERVARERVKLLGNEDEDQGVVREKLRAQHAAAAARVKTAEAALTAVQERVDRLARADREAGEHIAVAVARVESERGFTVDAARTATKAVAQARIAADRADVTVRQVDLPSYTGDGAMGSGKIWRPGEIDPEQVLAALPVGVREGARAVVEELFSEAKIGDTLRRLADEGIRVEVDSRELHVKFERTAATPVQVPKGEGFTEWGIRSADASRTITREGGPQYSLPAGIPNMLGAATEGVARSWLLHPSVRPSWGTNEQRNLVSTTEFSRGINSRPAERHSIQVPERHFVVDGRFVIDVRVGEEPPRTYRSDVIRDVALVRFYGEDVPPATINPGPGGPVLPVPASALHEVFVVPQAAAVRRIRQRVLAGLPLPKVGVEVRDAVSRELAEDAAIVKFGEITGGGYRSSPLRLPGATLNTLSLEVSAALRSVRRVDDRVVPDVNLRQIAGGDTKSDTSVAQSASAEASASVGPALVTELKEQRRGLGAYTVITPFTVSGAAESGETLTQVVGTSSGKKTVASIEGDSVLVEATLDMRVQRYSTDPALEGSDTVAEKVFLWMPVEEFARLEEISAAHSALRVAEEHDGPHEPPAVPERLRQSQNFRDLVDRVRPEVTRTPAETETEAVTEAVTEAVTEAVTEAVTEAEAVTEAEAGGGDARLGNDRAEQLALSILADYGKRPEITIPVGGRRQPDMLAAGKSTGGGVVDRAPGIERVLPEVRRLLRESVGEELASLDHDLRSVVESLLSSAFGAPGLFREFSGELRGATETIRVGDRLVTIEVRPRLGALVGTGRVEKANVDVTARNAIRGEGKAKAGTKQRIGVESGATVGTKRKDFWRTLGFLATGSVQFSHSYTGTVGQSHKVHRRARFVGPAVTFDRRVTWSISVSTKTIPAETGQPEPSQTGQPEPQAGQPEPSQAGQQGSQAGQSGSWYRGLGLLGGWGRRSDEADSGGIELDTLSGDTVTAGSDSDSVGSFGGASASSSATTVSGSTVDGWTRVLVPEPLAPITEQGDLRNLGTVIRDFDYDDQDGNPFQVHVEFVMPQGVATPSTVLGEPIEAILEDRAGGQRQDLTTAGENSPDSLEAQFDQLVSPGGVVIAGSRVRLRLFDVHPVGTAAKKLNLEVGTEGGLKLDGQEMRGRGFEGRLRGSAWMLFGGKSSRAYVAPSLTGRGRFGEEEGATFGRGTQRRRVGRTTGATHLYRAHGVFEITSYGESGAAGSTETVVVGGGVEFLLSDIVAQRLRTHPVREPAAQGRPPRTRHLELPAGVEPKPAPVTEVRYPPEFVFSGAALGPTLVTEISNAHEVAPLIKSMISEHAPGFRSGRWLEVPTGIAGSVDTLASVNALAARFGQEATSGVPLLAARPYRGGTETIEFVIRARYAPDAVATPDKDTKSDTSFLHSEKRVHTVARSRAVGGGASVLVAGKGRGNLRRGGAHPQVGYDNESSRIQRDSESDTFKSRVLGTEAISYSYTWPTWFQVEMYRTWTPNAMLNTLLLNKPRQGIEMWAAMREDTRTPLQRGFTSEGTARYIIPGGLTTTTPPLPRPVRIGGRLVPAGGAQRLGPLPQDLRGVDVIPLALPGSERLFPWLAAVLAHPAPEPADDADPQTSEGSMRAPAGNGWVRPATLPAQMLWQLGGEEGLTAMMPDLLADPVVFPAMVETGMVWDDEHGLAVRLRFTGIEYVDSFTATGELTQEQKTEQELVQSEGGKTSAAVIGQATVDSGGPGASGEHGKLTGDMLFPGETSTLDPSVGLSATWSDPRVQKFTGGTTREVTTERRGLYHVYRAAEAVYTITGLTKRRVFSAALPGKTAEVEVTITNGGYFAVESTQAAAKNLPGPPPKPTTPATAPAPAAALGPAALPAVWTPHTGDEHAAGLLPKIRGHLVVGLTASGGTLTVPELAARIEQLPGWARRPIVLVGTDGSFDLADAARLRDTLGVDVIAADHEVWHAADGRVVTGNLSFVRGGAPTWSERAEAILGGEVRSATAGHWHLLSAAGGTRRLPGADLVAALASTGTPAQAGTAPRSDFRWGARSAPVALAIHGATDTADYTTWTRSPYHAAARPEGSKPLLVLGHDDTIIPNTEVTTLRDHTGADVLARVNRGRGPKWMLHRADGSRPRPVDPPTEVTPTPRPQPLLFAGPEDSPATIAQAARSAPHLPADIQPVGVHVTPDGLAVLPDDRKVTPEAFADEVRQHPRFVPGLTIALLGCAANRPPEPGQPTFAQRFARALRTWVWTTTDDVVQTTDKRVHATQVTVAGDGTLLPQFKNGQGTGHWDLLDPEGQPLRTAGPDLAAAVTPDGTAPPRYPEGTHPTPVIRWTGRNGKRSYVKTAEQKEKYSATERQRYAADPSFREKKAQVRRDRTVLLRERDELVLGAEVLLGAAQARLAALPVGDGARQAVLGRIGDLQGVLDDLRKETSAQILRDEEAARASAAQTEEEREQRRKETKTENQRLRRGRLSAAQREKERERAREYDKRYRAGLGDAQREDQQRNNREMTRLKRERDKLIDEAEKLLGEAEARLAEVEARLAALPWSDKTRQEELERARQEELRCIEDLQGVLDDLRKEEIPVIRRKEAELWAIEEDSGSSDVASVGGRVAASVPDAAQMTESGAREKAASDEQARASLADWVAQVRASLKGIKSRQDWFALQDRDFVLQWGQELPTLDEAMRDEREELQRQLDEITGDVVVELKRLVGLLDGHLAALPADSLPKVRAQFALAKAAAEQGSWPLEQVYKIASKLGGMLEMEQSLRNYRLGLARDGDSRRAIDEGGARTAQDGSRPWPVDPPIEVTHPPRPQPLLFAGPGDSAETIAQAERSAPDLPGTQPVGVHVTPDGLAVLPDGRKVTPEAFADEVRQDPRFVPGLTIALLGCAANRELEPGELTFAQRFARALRTWVWTTTDDVVQTKDKRVHATQVTVTGDGTLLPRFENGLGTGHWDLLGSEGESLWTAGPDLGAAVTLGGSAPPRYPDGTHPTPVIRWTGRPKLTDEQRQRKTANQRLRRGRLSDAPSAQPDDTAPDAMDRNP
>NZ_CP040605.1|WP_168588083.1|5669058_5670090_+|hypothetical-protein
MTTPDQKADVRAALHEVLLRQAGFAPDELVTQARAWLADDRFDEVARAVVSTVARYVLPLTVEDLDVLVTVSEAEGVSLDVLESIEPTIDDPPLVWRFSAQPPDSVDSTDDSAVAALIDVLGEEPAAHGMWRAWRMVPDGAPYPPPRPVYVVEADDDDLPALTARLQEALVAAGEAAPQVEVTPAVGPVPTYQQAARAYGALLWAATEAPEITVARVFDAVDPISGPSFAPDHPRMDNEAERGQILDYLRAGTALMITTATLEDVVDPTRGAVVPMSFRTDGTWIWPDTIAYYLEHHHLAPDPDLLAHIRDAGLLPPELDTVAIHRAMDVLRRPPETEPVWTR
>NZ_CP040605.1|WP_168588084.1|5670686_5671520_-|hypothetical-protein
MKRPSWAPLDVDMNQPSIARIWDWFLGGAHNFAVDRQVAEEMLQLMPEGPQMAHINRMFLRRVVQLCVAEGVTQFLDIGSGIPTVGNVHETAQQADPECRVVYVDIDPVAVAHTRRLLADNPRCAVIQADLREPEEILAAPELRDLLDLDRPVALLMIAVLHFVHDEEDPLGLIARYRDALAGGSFFAIAHGSRSTERMPSEHLYAARSKYERSVAQVSLRSQPEVEAMFAGFDLVSPSVVWLPVWRPANGETPEDSAAPNAGYGGVGRKPRTNRPQ
>NZ_CP040605.1|WP_168590368.1|5672391_5674242_-|GntR-family-transcriptional-regulator
MVGRPRNAVVLTDTERAALLKWTRSRTCSRALALRAQIVLCCEHERTNTAVAQSLGISRGVVGKWRSRFLDQRLDGLHEQPRPGRPRAVDDDAVATVLIRTLAPAPGARHAWSTRSMAAETGLSQTTVNRIWRAHRIHPAAGSSPRRADQASLLPAEIHDVVGLFLDPPVRVLAVSATPHRTPLRDRRPAGRGADRRSAETRNLFAVANAFASLRGMTAGMSGEGVPLRAFLGHLDRTVAASMNVHLLAGGLDEPALRTVDEWLHSQPRFRCHSAPDQSSWIDEIDFLLANNPLPGHENLFGFAASLTKVRNDVRAWCRTWTPRTSPYSWAKSPRALWSGDAANRRLNNDSKSASETTPEQPGRDLEPTSAIPDDPATASGTTDRVVHLVREALAAGQYHAGERVKEAPLAARLGVSRGPIREALRILAEEGTLERLPNRGAAVPDVSATNILDLYAVRASLGALVMRRVAVLGQAHLQPVNTALAEVRAAARNSDDVRIGEADLCFQDAIARTANLPQASSFFERLTMRLRMFISVLRLGYAEAGDLIARENAAIFDALRNGDGNEAARLWRVKVERSVRYMVAQLPRDHFDPDLWITIAGKPNPRPSDPRNLPR
>NZ_CP040605.1|WP_168588085.1|5674530_5675889_+|MFS-transporter
MSSSIIDDQPYGRFHRKLFFLSAGGPFLDGYILSVIGVAITGATRELGLTSFAEGLVGAAALVGVLLGGFVFGWVTDRVGRQVMYTIDLIALVAASALSLFVTEAWQLVLLRFVAGVAVGADYPIATSLLAEWLPAHRRGRTMGALVAAWFVGASASYAVGYLVAAAGGEDLWRWVLASAAVPGLIILLARIGTPESPRWLLRHDRPQDAAEAIRTALGRYPTEQELARLAETEPAKSSRLSDVFTGGYLRRTLFVGGFWLCQVAPAFAIWTFYPVILGAYGFEAGDTALLWSMVVSLVTLAGCVPCIRWVETYGRRPVIIWTFVGVTVSLAALGSFPGMAAALAILMFVVNALAQGGGNILQWIYPTELFPTDIRASAVGVASAISRIGAAAGTYLLPVGLEAIGLGPTMLVGAGLSVIGTAMCVAWAPETKGQALHESAAVPQQSEARAG
>NZ_CP040605.1|WP_168588086.1|5675899_5677939_+|NADH:flavin-oxidoreductase
MSVTRDPLLTPFRIKNLVLRNRIVSTSHEPGYGEDGMPTERYRAYHVEKARGGVGLTMIGGSSVVSVDSPPSFGNLHLYSDEIVPWLRQLSDEVHAEGAAVMCQITHLGHRTSNYTESWLPTVSVGNLREPAHRAFTKQAEIADLERIAADYAAAAARCEAGGLDGIEIQAYGHLLDSFWSPALNNRTDDFGGSFDNRMRFPLQVIAAIRAAVSDEFVVGIRMAVDEQLPGGVDEDEGLAIAAVVVDAGIDFISVIRGHIATESGLSDVIPPMGEASAPHLDLAARVKRKIDVPIMHAAKIADVATARHAIDEGLLDLVGMTRALMADPHLVAKIEAGQEERIRPCVGASLCIDAAYIGEPAYCIHNPSTGRELRLPHRISAAPQAKNAVVVGAGPAGLEAARVLAERGHHVTVFEAAPEPGGQLRLASRVQRRRDLIGIVDWRVAECTRAGVRFKFNHLVEADELRGLAPEVMIIATGGVPNTDFLDFGADLVHDTWDIISGAVLPTGSVLVYDDHGGHPGLDVVELLAGSVAQVEWASPERTVAVDVGSVNAPPYLRTMLNHDVRISLMHRLVGVQRDGDALLATFTSDPTRRSFTRRFDHVVVEHGTLPNAELYEQLKPHSTNEGEIDYAKLLDRSPQDRLRNEDGRFQLFRIGDAVSSRSVHAAVLDAFRLCSAV
>NZ_CP040605.1|WP_168588087.1|5678240_5678414_-|DUF397-domain-containing-protein
MLTQQWIKSSYSSANGDCVELTTTLDAIRDSKDPHGPTLSVDVSTFVRAVQQGRFDR
>NZ_CP040605.1|WP_168588088.1|5678492_5678666_-|DUF397-domain-containing-protein
MNPKYWRKSSYSNVNGNCVELTTTLDAIRDSKDPHGPTLSVNVSTFVRAVQQGRFDR

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Crispr_ID: NZ_CP040605_20

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_20

5647206-5647303

Orphan

Consensus_repeat	Method
TGGTTCGGAGTTGCGGGCGGCGGTCAACGACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040605_20

>merge|NZ_CP040605|20|5647206-5647303|CRISPRCasFinder
TGGTTCGGAGTTGCGGGCGGCGGTCAACGACTTCCACCGTGATCGCGGCAGGCAGGTGGAGGTGCGTGGTTCGGAGTTGCGGACGGCGGTCAACGACT

>NZ_CP040605|20|19|5647206-5647303|CRISPRCasFinder
TGGTTCGGAGTTGCGGGCGGCGGTCAACGACT	TCCACCGTGATCGCGGCAGGCAGGTGGAGGTGCG
TGGTTCGGAGTTGCGGACGGCGGTCAACGACT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168588071.1\|5624062_5624701_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373064
NZ_CP040605.1\|WP_168588081.1\|5655502_5656759_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168588077.1\|5630095_5633440_+\|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|239160
NZ_CP040605.1\|WP_168590367.1\|5633708_5634983_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379730
NZ_CP040605.1\|WP_168588072.1\|5625628_5625796_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168588076.1\|5628582_5629956_+\|phenylacetate--CoA-ligase-family-protein	unknown	unknown	gnl\|CDD\|274074
NZ_CP040605.1\|WP_168588083.1\|5669058_5670090_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168588075.1\|5627911_5628577_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|188483
NZ_CP040605.1\|WP_168588073.1\|5625782_5626289_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|315923
NZ_CP040605.1\|WP_168588074.1\|5626231_5626444_-\|winged-helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379282
NZ_CP040605.1\|WP_168590368.1\|5672391_5674242_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NZ_CP040605.1\|WP_168588078.1\|5635270_5644372_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223496
NZ_CP040605.1\|WP_168588082.1\|5658834_5668980_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274009
NZ_CP040605.1\|WP_168588084.1\|5670686_5671520_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|252734
NZ_CP040605.1\|WP_168588085.1\|5674530_5675889_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|365860
NZ_CP040605.1\|WP_168584616.1\|5622528_5623365_+\|transposase-family-protein	unknown	unknown	gnl\|CDD\|372577
NZ_CP040605.1\|WP_168588088.1\|5678492_5678666_-\|DUF397-domain-containing-protein	unknown	unknown	gnl\|CDD\|377231
NZ_CP040605.1\|WP_168588087.1\|5678240_5678414_-\|DUF397-domain-containing-protein	unknown	unknown	gnl\|CDD\|377231
NZ_CP040605.1\|WP_168588080.1\|5651798_5655542_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274009
NZ_CP040605.1\|WP_168588086.1\|5675899_5677939_+\|NADH:flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240085

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168588071.1\|5624062_5624701_+\|hypothetical-protein	gnl\|CDD\|373064	pfam14430, Imm1, Immunity protein Imm1. A predicted immunity protein, with an alpha+beta fold and a conserved C-terminal tryptophan residue. The protein is present in a wide range of bacteria in polymorphic toxin systems as an immediate gene neighbor of the toxin gene.	6.48968e-05
NZ_CP040605.1\|WP_168588077.1\|5630095_5633440_+\|molybdopterin-dependent-oxidoreductase	gnl\|CDD\|239160	cd02759, MopB_Acetylene-hydratase, The MopB_Acetylene-hydratase CD contains acetylene hydratase (Ahy) and other related proteins. The acetylene hydratase of Pelobacter acetylenicus is a tungsten iron-sulfur protein involved in the fermentation of acetylene to ethanol and acetate. Members of this CD belong to the molybdopterin_binding (MopB) superfamily of proteins.	1.64659e-91
NZ_CP040605.1\|WP_168590367.1\|5633708_5634983_+\|hypothetical-protein	gnl\|CDD\|379730	pfam15567, Imm35, Immunity protein 35. A predicted immunity protein with an alpha+beta fold and a conserved tryptophan residue. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, usually containing a protease domain such as Tox-PL1 and Ntox40. In some instances, it is also fused to a papain-like toxin, ADP-ribosyl glycohydrolase and a S8-like peptidase. Based on these associations the domain is likely to be a protease inhibitor.	8.58851e-19
NZ_CP040605.1\|WP_168588076.1\|5628582_5629956_+\|phenylacetate--CoA-ligase-family-protein	gnl\|CDD\|274074	TIGR02304, conserved_hypothetical_protein, putative adenylate-forming enzyme. Members of this family form a distinct clade within a larger family of proteins that also includes coenzyme F390 synthetase, an enzyme known in Methanobacterium thermoautotrophicum and a few other methanogenic archaea. That enzyme adenylates coenzyme F420 to F390, a reversible process, during oxygen stress. Other informative homologies include domains of the non-ribosomal peptide synthetases involved in activation by adenylation. The family defined by this model is likely to be of an adenylate-forming enzyme related to but distinct from coenzyme F390 synthetase.	2.58311e-30
NZ_CP040605.1\|WP_168588075.1\|5627911_5628577_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	3.59278e-19
NZ_CP040605.1\|WP_168588073.1\|5625782_5626289_-\|hypothetical-protein	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.93763e-18
NZ_CP040605.1\|WP_168588074.1\|5626231_5626444_-\|winged-helix-turn-helix-domain-containing-protein	gnl\|CDD\|379282	pfam13592, HTH_33, Winged helix-turn helix. This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.	4.79709e-13
NZ_CP040605.1\|WP_168590368.1\|5672391_5674242_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	3.43658e-35
NZ_CP040605.1\|WP_168588078.1\|5635270_5644372_+\|hypothetical-protein	gnl\|CDD\|223496	COG0419, SbcC, ATPase involved in DNA repair [DNA replication, recombination, and repair].	2.7316e-13
NZ_CP040605.1\|WP_168588082.1\|5658834_5668980_+\|hypothetical-protein	gnl\|CDD\|274009	TIGR02169, chromosome_segregation_protein_related_ptotein, chromosome segregation protein SMC, primarily archaeal type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	2.34826e-14
NZ_CP040605.1\|WP_168588084.1\|5670686_5671520_-\|hypothetical-protein	gnl\|CDD\|252734	pfam04672, Methyltransf_19, S-adenosyl methyltransferase. This family contains a SAM (S-adenosyl methyltransferase) domain, with a central beta sheet with 3 alpha-helices on both sides. Crystal packing analysis of the structure Structure 3giw suggests that a monomer is the solution state oligomeric form. An unidentified ligand (UNL, cyan) was found at the putative active site surrounded by the residues His57, His170, Phe171, Tyr216 and Met22. The UNL is likely to be a phenylalanine or phenylalanine-like molecule. (details derived from TOPSAN).	9.6299e-95
NZ_CP040605.1\|WP_168588085.1\|5674530_5675889_+\|MFS-transporter	gnl\|CDD\|365860	pfam00083, Sugar_tr, Sugar (and other) transporter.	1.20054e-43
NZ_CP040605.1\|WP_168584616.1\|5622528_5623365_+\|transposase-family-protein	gnl\|CDD\|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.95997e-24
NZ_CP040605.1\|WP_168588088.1\|5678492_5678666_-\|DUF397-domain-containing-protein	gnl\|CDD\|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	5.09896e-16
NZ_CP040605.1\|WP_168588087.1\|5678240_5678414_-\|DUF397-domain-containing-protein	gnl\|CDD\|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.31648e-15
NZ_CP040605.1\|WP_168588080.1\|5651798_5655542_+\|hypothetical-protein	gnl\|CDD\|274009	TIGR02169, chromosome_segregation_protein_related_ptotein, chromosome segregation protein SMC, primarily archaeal type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	9.06884e-10
NZ_CP040605.1\|WP_168588086.1\|5675899_5677939_+\|NADH:flavin-oxidoreductase	gnl\|CDD\|240085	cd04734, OYE_like_3_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 3. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase. One member of this subgroup, the Sinorhizobium meliloti stachydrine utilization protein stcD, has been idenified as a putative N-methylproline demethylase.	9.56665e-168

>NZ_CP040605.1|WP_168588078.1|5635270_5644372_+|hypothetical-protein
MFSSIMVPEGVRRLFQVLTGEDMTDADEGALFAVADVLESGAAGLGEVRALVAELVGKVRTEFSGKAADRFADGLGIFDGLLSSGQAGLLDLAAFVRKTSQQVRYLKLVTIYGLELLAVEMSWAMQFAGATAGATLAWLAARMAVMRFLLTSWWRQLFMRLAMMAAGGVVFNVLPDVQAQLTMRGEESAEKWDRTLTEQAAGMGAFSALVALPMSAVGGLVSNTLTKVLVKGLGDDVDAAILEAAAKKAVAEHAELYPVSAMAKFADAVGKSLDNYAGMSVGAMWLARFGHSVGEALAGSLSEFFGEALYAAATGQKVTWNPFSLTAGFFETVFSGVGNLAGLALRGKLHPEGPSPYLEGTGGGGGGSDDGGGSGGEKTPLPGAGSGSQTGDIPGSPDKDSVFIPSDASDSSDGSRSDRWAGSDSGAGSDSSSVSDVDSVFSDTGSVDSAAVSVPSGDGLVVPGSAVVSAVVVGGTDGKDGTDGTDGKRGADGSVPGRDAAGDVPVVPGSGQHRPGTPPPAYSSGVPGVDPDRPGTPLPAHFGGVPGVGPDRPGTPPPPYSPGPGGDQAVPGKRPLEVSASKTPDSPTVTPHASDVPADAARPETGKPGSVVGPDGRVPAGHPASETVGSGSAADSGSGVSGGHPESPSGVTGRDGDPGADSVAGRGDAHRQDGAVVSPDSATLPGEGSPAAPSLHRDPAAVLPAGLPADTVRVPVPANVVAGDRLGLAEFVRSHGADSPGGPVLLVSPSDPNAGVVVTRGQGLALARDLGRNVVAMMPGQAGREPQFMVFPADRSRPKSLAGPGAAVLAGGRSGGVAGLADASATVPAASGGKTRGEAPAAGTGSAQARSVAGEVQPASTTPGAGAGMVRDTSGIPVGQWTQEELVRAIARARELGLSSDEKDAAAQIVWLAHDVQVLARGDAVVPLEDVVALVAAKYHDLGKDHRDQVVKFSRALADWLGTRRSKPVIHAGAGPEGHTADGGPSGSSSAAVPRNVEGHRRRAETATAKRRTKIAELEDLLKPLRDEQASLEASLGRDEADAGSRTRGEELQGRIARWQAVLDGLKTKDQQVRARGAERTNKWRERQQRKSRAARLGAGGPSPAGRSDQIAGRSEEPSAAAELSELITNANAGLDSMRQQELPVDQLIDAVKPHMESFGGHDGLRDVMAHHMLRYPGDSEETRKFERKLHKLTTVRNWDEWYERDATRLDKWAGIVGRDAVDRLLADADMVLGSLRVSLRFRTVLAQWLGEHPGDRRGAQAVRGIMAGYLAGDPDLGVAVSGLTLDEFETAKAEEARWQEDRAANPAEAAAPMVRGFADDPALDVISRISSIQHKFEDVGQELRQWARTEDQDAVDLLYDQADQVLGPLKESEPFRDVMAHELLMRRNNLRDDQQLQRFMTNPQDDPQLRQLRWELARYLAGDLTGGADPDTADNLLSAGMGPLPEDIRSRGKLMYNRRLTIGKALSGLQDDAVNEVLRNAALEDLRRGKYSHDTLGKRFYRSGPWGGTVFVIRDLQDAVGSLRQVLAEAETNTDRRDEYEPKIAEWLNLRGFLDPTAIRSRATEVADAVRLLRQENANREPTQDGRMLPVFDNGEGTGQWYLRSRDGELEARGSELRTAVNDSAVPTDPEGAPPAPVFRWAGTPGPSRTRTAGNEERKARGRERWHREKAVEAARVAELEAFLKRANSGQDSWAASQESDAANPRQRGDLQREVRDAQAELKKIADDRTAKKAKHAADQKSSEERKRRVVADARASLAAARAGRAELEELPGFDREDRRRWEALQREEAAALEVLHDHELMRDQVAVRKRKLEDRYKDEWAQESKSLRELMARQAKLEVLTARDETETRGEELAELEGLPGRIAEVQAKLPGIAKLEAERKANHAEKEKKNKARRKANTLLATFRTRREELVESDAVQGPEWEEVQGSIAALEAELAAIANDDMGSGATARGNGGADREMPAGVVELVGLVGRVEGHLSVLPAGFRRDLHDQVEEAWAMAKKGSWIRGDPARIDSQLERMRDLERWLGEVVRSPGVVELEGLVGRVEGHLSMVPADVLLDVRAGVVKAKAMARQGSWTPKDRAWIDSKLAGMRKGERWLAEVVSSPGVVEFVGLVERLEGHLSVLPADFRPDVRAGVVQARVMARKGNWTREDLSLIDSELGRMRKLERWLRLEPVVFGVDPGVVKLASGLRGVQVVGVHVTPDGQAQSADDVLETPEDFAARVLSDERFVPGVPVAFLGCGALRQPPGGEDSFAKRFEDASGVKLMLATEADVWHTDDGLIHATETAVTQDGRIFPVFDNNKGTGYWSLRNRGREVGALGSELRTAVNDFHRDRGRQVEARGSELRTAVNDSAVPRHPEGAHSAPVFKWAGTPGPSRTSRTAENEEKKASTTEWRHRKKAEEAALVADGRALLEKLTTRQAELKALPGLDEEQTEEWNALLGRIAEVQANVAAVEQKGADRRARDAASERRRYERTKREKNGLVDARKVLLEQLMVQRAPLAVLAELTVLDTNQRAELEELDASIEEVRNELATIANEEQARKAQHAERMRKQRARKKRGQADALASLAAARAGRAKLKELPGFTEVLQADPATLPEFYKEPRRQWEALQREEAAALELLHEHERMRNQGVARMRKSEDRYKDEWAQESKSLRELMARQAQLETLMARNETRGEELAELAGLPGRIAEVQAKLPAIAKLEAERKANNAENDKKNRARKKANTLLATLKAQRAKLVESDSVQGPEWEEVQGSIAALEAELAAIENDDTGSGATARGNGGADREAPAGVVELVGLVGRVEGHLSVLPAGFRPDLHGHVEEAWAMAKKGSWTPADRARIDSQLAGMRELERWLGAVVRSPGVVELVGLVGRVEGHLSMVPADVLLDVRAGVVKAKAMARQGSWTPEDRAWIDSKLAGMRKGERWLAEVVSSPEVVEFVGLVERLEGHLSVLPADFRPDVRAGVVQAKAMAQKGNWTPEELSLIASNLGRMRKFERWLRLEPVVFGGEMMISGWLRGRWSWPAVCGVCRWWVCM
>NZ_CP040605.1|WP_168590367.1|5633708_5634983_+|hypothetical-protein
MNELAERARTWLHDTYGQRVVLRDEEAILSTERVAFFGCRYVESDEPMLAATICVPRDGADPFPASNAGPLDEALNVSRSEPRAWRWRVNARNCVIATDAAVNCWPASALPWDPAGETPGWWDRMLAAYFPDAEVLICSTWADASRAIVDGGVGTRAVVWLRRQLGGRELAGHLLYADYADDAVVFLDGLRGTVAEQNDAEVAELVVARFRRRQDESVGGLLPSEAAADEFAGAVEKAQAWLAYRYDGEVELVGPDPADETERGWLFACTTRSFQRSGDWRDQMLDAAVVVPKAAGEQPFGLPNRDPWTWLDDWNAGKPGLMPPPEPAQAAWFGPMVAELGPVVGSSVHEHWFGVLEEIASFPARTQALVWLRRRDPRGRESVGHLLVAVNETEGVQLFDPMDGRAQPLIETVPFEFRVMRFDS
>NZ_CP040605.1|WP_168588077.1|5630095_5633440_+|molybdopterin-dependent-oxidoreductase
MSEEVRGFCTLCRSRCGAVYTVDAGALTSVRPDPEHPTGAALCPKGRAAPEIVRSPRRLTQPLRRTRPKTEPDPGWQAIGWDEAMREIAEQLARIRDASGPEAVAFAVTSPSATPMSDSIDWVERFIRLFGSPNICYATEICNWHKDFAHAFTFGCALPTPDYAGADLAVLWGHNPAKSWLAQSAALAEARARGTSVAVVDPRRSTSALQADHWLRVLPGTDAALALGLANELIRTKAYDEGFVREWSNGPLLVRTDNGRFLRAEELDPELDGFVVWDEEIGSAVTYDTQRAAAHPERFALLGRRRVATRHGDVECVPAFERYAAACAAWPLERTSATTGVEVRALHEFARDLANAGSVAYYGWTGVGQHANATQTDRAIATLYSLTGSFDAPGGNVVLPKLPVNQVTTPGQLTAEQREKALGASEFPLGPPTQGWVSARALCESVLSGQPYRVRALVGFGSNLLVSQPNPGRTAEALRSLEFQVHLDLFANPTADFADIVLPVNSPWEREAIRAGFDITQRAQEHVQLRPRLVEPVGQSRSDTDVVFDLAQRLGMGEQFFDGDITAAWNHQLAPLGVTVDELRRRPGGMQIPLDTRYRKYADVGDDGQVLGFGTPTRRVEMYSEQLADHGYSPVPEHVTPPGTDTAPLVLTCAKNGYFCHSQHRGISSLRKRSPEPVVDISPQAAAERVISDGQWVSIVTDNGTVRMRARIDPALHPRVVVAEYGWWQDAPDLGLPGSDPLQQGGHNYNLLISDDVHDPISGSIPMRSFGCDVRPEPTAAWPGLRSFTVADIAAETDGVRALRLRPSDGGVLPDFRPGQHITLNHLDTTRSYSLIGAARVDERDAYTVAVRHVPDGDFSTFVHERLRPGAEVSVAAPAGSFVIPAEIDLPVVLLAAGIGITPFLSYLETLAATGGTVPKVVLHFGNRNQHSHPFGDRIRELQRAIPQLTVIDHYSRPAGEGSAFRSGRLHAGQVDAELIRQRARFYLCGPEEMLRDLSTGLVARGVPRFEIFAEKFHAAAREVAIPDDAAAEVHFARTGKTLRWRKADGPLLQFAEDGGIPLPSGCRLGQCESCAVTVLNGRVAHLVAPTDDLSEDACLTCQAVPVSDLTLDA
>NZ_CP040605.1|WP_168588076.1|5628582_5629956_+|phenylacetate--CoA-ligase-family-protein
MGDSVRELARDARQAVREGPVGIARHQRAHLTDLVAHARANSPYYRELYRDLPDGVDDPTVLPVTSKKELMARFDDWVTDREVTREKAEAFVADPDAVGKRFLDKYLVATTSGTSGLRGLFLLDERSMNMEGALGTRASGVLGAGDAIRMLARGGRTAIVTAPGGHFFTVAGTARFQRDHPRLGRRLRVFSIHRPLPELVEELNRFNPAVLSGFLGMLTLLAGEQEAGRLRIRPALIIPGGETLTTGLGKRLATAFGAKVRAAYAATECSFLSMGCAHGWYHVSSDWAVLEPVDADYRPTPPGELSHTVLLSNLANRVQPFLRYDLGDSILLRPDPCPCGSVFPAIQVQGRAADLLTFPAEDGEPVTMSPMLFGTVLDRVTGIGQYQVVQTASSTLRVRLRPADSAAAEQVWQTVRGEITHLLKEHEVADVTLERADEAPQQEPGGKFRRIIPQTKP
>NZ_CP040605.1|WP_168588075.1|5627911_5628577_+|TetR-family-transcriptional-regulator
MYVRGVEESRRERKKRLTRQRIVLAAIRLFDKQGYEETTVTQVAEAADVDPKTFFNYFRTKDEVLFNELDLEFDVLLAAIRDRRSEESPGEVLRRAVQEYAAHRRPNVPRREPAEVSAAARLALTTPALQAKGAYLLLDLQQRIAAELLNAFPGELDPVTAAAMTGSVLGAIQQASLASAKLGRSQQELWEAAEHALDIATNGLLSVRPRTRDQKQTEERI
>NZ_CP040605.1|WP_168588074.1|5626231_5626444_-|winged-helix-turn-helix-domain-containing-protein
MWTRKAVAELIRVRHGVVLSLRTVGDSLRCWGVSPQRPIRRAYERDPEAVCWWLEEAIRPSPPAPAARAR
>NZ_CP040605.1|WP_168588073.1|5625782_5626289_-|hypothetical-protein
MAGGGYPAIAARARREGAVILWLDQTGIRSDAAVGRTWAPAARTPVVGKTGETVQRDHLDRQVQVIVDGHPVHRRKTVRKWVDDHAAAIEMHFLPGYNPELNPDEIRGADLKRTMSTGTAQKIRDESKQAVRSFLHRLHKSPDQVRSYLGKPDVRYARLTSHNCPTNQ
>NZ_CP040605.1|WP_168588072.1|5625628_5625796_+|hypothetical-protein
MEEQELLVISVRQRSVVQDRLNLVHGDPSKSGGGDGHGEQGGDGLNIPEWPVIDS
>NZ_CP040605.1|WP_168588071.1|5624062_5624701_+|hypothetical-protein
MTVHGTTTTAGRSPRSTGGKHERFWADVLNDQEVLLTPTMDIEEIIRGLAEHDQECQRPEAGLAWFLLHEPDEDAPTLTLGVRGTIGSLMWFDATSALVPADGTNAGYVGYFTMDGHMMVMSPHAELPIARVHEALREFARTQQLPSPCCFGTGWQVSTVLPRGDVAVRAGFSELAGVGGYHFVGGTPSEATVGHGGGDQEFGQVVADGRRR
>NZ_CP040605.1|WP_168584616.1|5622528_5623365_+|transposase-family-protein
MVTYSAKLDVPRELVVFLSRLLAGERRRKGTRKGRRALTTFWQAVLVLRWFRDDTDITKLARDHGVARATGYRYVDEGIKALAAQAPDLHDALQRAKDNGDAYLILDGKNFSSDRLGEKTTSAKGAEIDLWYSGKTREQAGNIQALTDPDGFPLWASDVEPGSIHDITAAENHVLGALYWAYSQLNLPTLADGGYQGAGAGVLTPIKRPKTSKGRPLDVDNQTYNKLLRGLRALGERGFALLTGRWRVLRHFTTSPRKIGLIVKAALVLTQFEHGRLA
>NZ_CP040605.1|WP_168588080.1|5651798_5655542_+|hypothetical-protein
MTPDGQAQSADDVLETPEDFAARVLSDERFVPGVPVAFLGCGALRQPPGGEDSFAKRFEDASGVKLMLATEADVWHTDDGLIHATETAVTQDGRIFPVFDNNKGTGYWSLRNRGREVGALGSELRTAVNDFHRDRGRQVEARGSELRTAVNDTPVPRHPEGAPPAPVFKWAGTPGPSRSRTAENEEGNARGRTRWARDKEKQAALVADGRALLEQLTTRQAELKALPGLDAEQAEEWNALPGRIAEVQANVAAVEQKEADRKARNLASHKRKYGRTKRETNELVELLEQLMVQRAPLAVLAELTVLDTDQRAELEEWDASIEEVRNELATIANEEQDRKEKNAERMRKQRARKKRGQADARASLAAAEAGRAKLEELPGFTEVLQADPATLPDFYKEPRRQWEALQREEAAALEVLHDHERMRDQVAVRKRKFRDRYKDEWAQESKSLRELMARQAQLETLTARDETRGEELAELAGLPGRIAEVQAKLSAIAKLEAERKANNAEKVKKHRARKKANTSLATLRTQRAKLVESVDVHGEEWEKVQGSIEAVEAELAAIENDDTGSGATARGNGGADREPPAGVVELVGLVGRVEGHLSVLPTGFRPDLHGHVEEAWAMAEQGSWTPEDRAWIDSQLERMRDLERWLGEVVRSPGVVELEGLVGRVEGHLSMVPADVLLDVRAGVVKAKAMARQGSWTPKDRAWIDSKLAGMRKGEQWLAEVVSSPGVVEFVGLVERLEGHLSVLSAGFRPDVRAGVVQAKAMAKKGNWTPEELSLIASNLGRMRKLERWLRLEPVVFGVHPDVVKLASGLRGVQVVGVHVTPDDGQAELAAGVSETPEDFAERVLGDERFVPGVPVAFLGCGALRQPPGGEGSFAKRFEDASGVELMLATEADVWQTADGLIHATETVVTQDGRIFPVFDNNKGTGYWSLRNRGTEVGALGSELRTAVNDFHRYRGRQVDARGSELRTAVNDSAVPRHPEGAPPAPVYKWAGTRGRSRTIRPAKNEERNEKERARRARNKEEEKKEAARVAELEAFVERANSGQASLAASQEPDATEPRQWGELQREVQDAQAELKKIADDRTARRAKRAGYQKSYEERKKRKVADAEELLAAARAGRTKLEELPGFTAVLEANPVRLPESLKKSRSKWEALLEDEAASQEVLQKHERTRNQRNARNTRSNKRYQDEWAQESQSLRELMARQAELEALTARNETRGRSWRSWRSCRGVSRRCKQSCPRLRNWRRSGR
>NZ_CP040605.1|WP_168588081.1|5655502_5656759_+|hypothetical-protein
MPAIAKLEAERKVKNAEIEKKNKARMKANTLLATLMTQRAKLEESGAVPGTEWEKVEGSIAAVEAELAAIENDDMGSGATARGNEGADREAPAGVVELVGLVGRVEGHLSLFPEDFRPDLHDQVEKAWAMAKKGSWTRGDPPRIDSKLAGIRELERWLSEVVRSPGVVELVGLVGRLEGHLSKLPAGFRPDVRAMVAQARAMAQQGSWTPEDRRLAGMRKVERWLAEVVSSPGVVEFVGLVGRLEGHLSKLPAGFRPDVRAGVAQAKAMAQKGNWTPEELLLINSQLERMRERERWLDEVVRSSGVVELGGLVERVEGHLSVLPADVLLDVRAMVVQARAMAQQGSWTPEDRRLAGMRKVERWLAEVVSSPGVVEFVGLVERLEGHLSVLSAGFRPDVRAGVVQARAMAQKGNWTRRS
>NZ_CP040605.1|WP_168588082.1|5658834_5668980_+|hypothetical-protein
MPTPSADDARAETDEDMQSEFDEDYNVRDSDEQRSEVPERFPSSVSGQVLGAGVEEIPAGIMVSPSDLGEDLVAVARALPVEDGVLAVVAKGDGHGGVLLGGKSVDAQRLASLIQGGLRGKRKIRLYACEVSEEFATALDGASGVEVIWTRGLVWFGPDTKGFSSMVGGWYLDEYFTLRPDLTEEVPWVTTRPEAWPPGQSPSDVSLPPGRRGLSPRWVHLRAETARFRTGPQPDLAWLRESGQTAKVVQARSAITAADDRLTQVYSMVDAPVPEEPATTVTAAGSAETDVLVKAATDVTTSAAASVERAARQAGKWTAAQQELTAATQRQGEVRAELKAAAQDLGAAQKDLVQKQAEERVARERVKLLGNEDEDQGVVREKLRAQHAAAAARVKTAEAALTAVQERVDRLARADREAGEHIAVAVARVESERGFTVDAARTATKAVAQARIAADRADVTVRQVDLPSYTGDGAMGSGKIWRPGEIDPEQVLAALPVGVREGARAVVEELFSEAKIGDTLRRLADEGIRVEVDSRELHVKFERTAATPVQVPKGEGFTEWGIRSADASRTITREGGPQYSLPAGIPNMLGAATEGVARSWLLHPSVRPSWGTNEQRNLVSTTEFSRGINSRPAERHSIQVPERHFVVDGRFVIDVRVGEEPPRTYRSDVIRDVALVRFYGEDVPPATINPGPGGPVLPVPASALHEVFVVPQAAAVRRIRQRVLAGLPLPKVGVEVRDAVSRELAEDAAIVKFGEITGGGYRSSPLRLPGATLNTLSLEVSAALRSVRRVDDRVVPDVNLRQIAGGDTKSDTSVAQSASAEASASVGPALVTELKEQRRGLGAYTVITPFTVSGAAESGETLTQVVGTSSGKKTVASIEGDSVLVEATLDMRVQRYSTDPALEGSDTVAEKVFLWMPVEEFARLEEISAAHSALRVAEEHDGPHEPPAVPERLRQSQNFRDLVDRVRPEVTRTPAETETEAVTEAVTEAVTEAVTEAVTEAEAVTEAEAGGGDARLGNDRAEQLALSILADYGKRPEITIPVGGRRQPDMLAAGKSTGGGVVDRAPGIERVLPEVRRLLRESVGEELASLDHDLRSVVESLLSSAFGAPGLFREFSGELRGATETIRVGDRLVTIEVRPRLGALVGTGRVEKANVDVTARNAIRGEGKAKAGTKQRIGVESGATVGTKRKDFWRTLGFLATGSVQFSHSYTGTVGQSHKVHRRARFVGPAVTFDRRVTWSISVSTKTIPAETGQPEPSQTGQPEPQAGQPEPSQAGQQGSQAGQSGSWYRGLGLLGGWGRRSDEADSGGIELDTLSGDTVTAGSDSDSVGSFGGASASSSATTVSGSTVDGWTRVLVPEPLAPITEQGDLRNLGTVIRDFDYDDQDGNPFQVHVEFVMPQGVATPSTVLGEPIEAILEDRAGGQRQDLTTAGENSPDSLEAQFDQLVSPGGVVIAGSRVRLRLFDVHPVGTAAKKLNLEVGTEGGLKLDGQEMRGRGFEGRLRGSAWMLFGGKSSRAYVAPSLTGRGRFGEEEGATFGRGTQRRRVGRTTGATHLYRAHGVFEITSYGESGAAGSTETVVVGGGVEFLLSDIVAQRLRTHPVREPAAQGRPPRTRHLELPAGVEPKPAPVTEVRYPPEFVFSGAALGPTLVTEISNAHEVAPLIKSMISEHAPGFRSGRWLEVPTGIAGSVDTLASVNALAARFGQEATSGVPLLAARPYRGGTETIEFVIRARYAPDAVATPDKDTKSDTSFLHSEKRVHTVARSRAVGGGASVLVAGKGRGNLRRGGAHPQVGYDNESSRIQRDSESDTFKSRVLGTEAISYSYTWPTWFQVEMYRTWTPNAMLNTLLLNKPRQGIEMWAAMREDTRTPLQRGFTSEGTARYIIPGGLTTTTPPLPRPVRIGGRLVPAGGAQRLGPLPQDLRGVDVIPLALPGSERLFPWLAAVLAHPAPEPADDADPQTSEGSMRAPAGNGWVRPATLPAQMLWQLGGEEGLTAMMPDLLADPVVFPAMVETGMVWDDEHGLAVRLRFTGIEYVDSFTATGELTQEQKTEQELVQSEGGKTSAAVIGQATVDSGGPGASGEHGKLTGDMLFPGETSTLDPSVGLSATWSDPRVQKFTGGTTREVTTERRGLYHVYRAAEAVYTITGLTKRRVFSAALPGKTAEVEVTITNGGYFAVESTQAAAKNLPGPPPKPTTPATAPAPAAALGPAALPAVWTPHTGDEHAAGLLPKIRGHLVVGLTASGGTLTVPELAARIEQLPGWARRPIVLVGTDGSFDLADAARLRDTLGVDVIAADHEVWHAADGRVVTGNLSFVRGGAPTWSERAEAILGGEVRSATAGHWHLLSAAGGTRRLPGADLVAALASTGTPAQAGTAPRSDFRWGARSAPVALAIHGATDTADYTTWTRSPYHAAARPEGSKPLLVLGHDDTIIPNTEVTTLRDHTGADVLARVNRGRGPKWMLHRADGSRPRPVDPPTEVTPTPRPQPLLFAGPEDSPATIAQAARSAPHLPADIQPVGVHVTPDGLAVLPDDRKVTPEAFADEVRQHPRFVPGLTIALLGCAANRPPEPGQPTFAQRFARALRTWVWTTTDDVVQTTDKRVHATQVTVAGDGTLLPQFKNGQGTGHWDLLDPEGQPLRTAGPDLAAAVTPDGTAPPRYPEGTHPTPVIRWTGRNGKRSYVKTAEQKEKYSATERQRYAADPSFREKKAQVRRDRTVLLRERDELVLGAEVLLGAAQARLAALPVGDGARQAVLGRIGDLQGVLDDLRKETSAQILRDEEAARASAAQTEEEREQRRKETKTENQRLRRGRLSAAQREKERERAREYDKRYRAGLGDAQREDQQRNNREMTRLKRERDKLIDEAEKLLGEAEARLAEVEARLAALPWSDKTRQEELERARQEELRCIEDLQGVLDDLRKEEIPVIRRKEAELWAIEEDSGSSDVASVGGRVAASVPDAAQMTESGAREKAASDEQARASLADWVAQVRASLKGIKSRQDWFALQDRDFVLQWGQELPTLDEAMRDEREELQRQLDEITGDVVVELKRLVGLLDGHLAALPADSLPKVRAQFALAKAAAEQGSWPLEQVYKIASKLGGMLEMEQSLRNYRLGLARDGDSRRAIDEGGARTAQDGSRPWPVDPPIEVTHPPRPQPLLFAGPGDSAETIAQAERSAPDLPGTQPVGVHVTPDGLAVLPDGRKVTPEAFADEVRQDPRFVPGLTIALLGCAANRELEPGELTFAQRFARALRTWVWTTTDDVVQTKDKRVHATQVTVTGDGTLLPRFENGLGTGHWDLLGSEGESLWTAGPDLGAAVTLGGSAPPRYPDGTHPTPVIRWTGRPKLTDEQRQRKTANQRLRRGRLSDAPSAQPDDTAPDAMDRNP
>NZ_CP040605.1|WP_168588083.1|5669058_5670090_+|hypothetical-protein
MTTPDQKADVRAALHEVLLRQAGFAPDELVTQARAWLADDRFDEVARAVVSTVARYVLPLTVEDLDVLVTVSEAEGVSLDVLESIEPTIDDPPLVWRFSAQPPDSVDSTDDSAVAALIDVLGEEPAAHGMWRAWRMVPDGAPYPPPRPVYVVEADDDDLPALTARLQEALVAAGEAAPQVEVTPAVGPVPTYQQAARAYGALLWAATEAPEITVARVFDAVDPISGPSFAPDHPRMDNEAERGQILDYLRAGTALMITTATLEDVVDPTRGAVVPMSFRTDGTWIWPDTIAYYLEHHHLAPDPDLLAHIRDAGLLPPELDTVAIHRAMDVLRRPPETEPVWTR
>NZ_CP040605.1|WP_168588084.1|5670686_5671520_-|hypothetical-protein
MKRPSWAPLDVDMNQPSIARIWDWFLGGAHNFAVDRQVAEEMLQLMPEGPQMAHINRMFLRRVVQLCVAEGVTQFLDIGSGIPTVGNVHETAQQADPECRVVYVDIDPVAVAHTRRLLADNPRCAVIQADLREPEEILAAPELRDLLDLDRPVALLMIAVLHFVHDEEDPLGLIARYRDALAGGSFFAIAHGSRSTERMPSEHLYAARSKYERSVAQVSLRSQPEVEAMFAGFDLVSPSVVWLPVWRPANGETPEDSAAPNAGYGGVGRKPRTNRPQ
>NZ_CP040605.1|WP_168590368.1|5672391_5674242_-|GntR-family-transcriptional-regulator
MVGRPRNAVVLTDTERAALLKWTRSRTCSRALALRAQIVLCCEHERTNTAVAQSLGISRGVVGKWRSRFLDQRLDGLHEQPRPGRPRAVDDDAVATVLIRTLAPAPGARHAWSTRSMAAETGLSQTTVNRIWRAHRIHPAAGSSPRRADQASLLPAEIHDVVGLFLDPPVRVLAVSATPHRTPLRDRRPAGRGADRRSAETRNLFAVANAFASLRGMTAGMSGEGVPLRAFLGHLDRTVAASMNVHLLAGGLDEPALRTVDEWLHSQPRFRCHSAPDQSSWIDEIDFLLANNPLPGHENLFGFAASLTKVRNDVRAWCRTWTPRTSPYSWAKSPRALWSGDAANRRLNNDSKSASETTPEQPGRDLEPTSAIPDDPATASGTTDRVVHLVREALAAGQYHAGERVKEAPLAARLGVSRGPIREALRILAEEGTLERLPNRGAAVPDVSATNILDLYAVRASLGALVMRRVAVLGQAHLQPVNTALAEVRAAARNSDDVRIGEADLCFQDAIARTANLPQASSFFERLTMRLRMFISVLRLGYAEAGDLIARENAAIFDALRNGDGNEAARLWRVKVERSVRYMVAQLPRDHFDPDLWITIAGKPNPRPSDPRNLPR
>NZ_CP040605.1|WP_168588085.1|5674530_5675889_+|MFS-transporter
MSSSIIDDQPYGRFHRKLFFLSAGGPFLDGYILSVIGVAITGATRELGLTSFAEGLVGAAALVGVLLGGFVFGWVTDRVGRQVMYTIDLIALVAASALSLFVTEAWQLVLLRFVAGVAVGADYPIATSLLAEWLPAHRRGRTMGALVAAWFVGASASYAVGYLVAAAGGEDLWRWVLASAAVPGLIILLARIGTPESPRWLLRHDRPQDAAEAIRTALGRYPTEQELARLAETEPAKSSRLSDVFTGGYLRRTLFVGGFWLCQVAPAFAIWTFYPVILGAYGFEAGDTALLWSMVVSLVTLAGCVPCIRWVETYGRRPVIIWTFVGVTVSLAALGSFPGMAAALAILMFVVNALAQGGGNILQWIYPTELFPTDIRASAVGVASAISRIGAAAGTYLLPVGLEAIGLGPTMLVGAGLSVIGTAMCVAWAPETKGQALHESAAVPQQSEARAG
>NZ_CP040605.1|WP_168588086.1|5675899_5677939_+|NADH:flavin-oxidoreductase
MSVTRDPLLTPFRIKNLVLRNRIVSTSHEPGYGEDGMPTERYRAYHVEKARGGVGLTMIGGSSVVSVDSPPSFGNLHLYSDEIVPWLRQLSDEVHAEGAAVMCQITHLGHRTSNYTESWLPTVSVGNLREPAHRAFTKQAEIADLERIAADYAAAAARCEAGGLDGIEIQAYGHLLDSFWSPALNNRTDDFGGSFDNRMRFPLQVIAAIRAAVSDEFVVGIRMAVDEQLPGGVDEDEGLAIAAVVVDAGIDFISVIRGHIATESGLSDVIPPMGEASAPHLDLAARVKRKIDVPIMHAAKIADVATARHAIDEGLLDLVGMTRALMADPHLVAKIEAGQEERIRPCVGASLCIDAAYIGEPAYCIHNPSTGRELRLPHRISAAPQAKNAVVVGAGPAGLEAARVLAERGHHVTVFEAAPEPGGQLRLASRVQRRRDLIGIVDWRVAECTRAGVRFKFNHLVEADELRGLAPEVMIIATGGVPNTDFLDFGADLVHDTWDIISGAVLPTGSVLVYDDHGGHPGLDVVELLAGSVAQVEWASPERTVAVDVGSVNAPPYLRTMLNHDVRISLMHRLVGVQRDGDALLATFTSDPTRRSFTRRFDHVVVEHGTLPNAELYEQLKPHSTNEGEIDYAKLLDRSPQDRLRNEDGRFQLFRIGDAVSSRSVHAAVLDAFRLCSAV
>NZ_CP040605.1|WP_168588087.1|5678240_5678414_-|DUF397-domain-containing-protein
MLTQQWIKSSYSSANGDCVELTTTLDAIRDSKDPHGPTLSVDVSTFVRAVQQGRFDR
>NZ_CP040605.1|WP_168588088.1|5678492_5678666_-|DUF397-domain-containing-protein
MNPKYWRKSSYSNVNGNCVELTTTLDAIRDSKDPHGPTLSVNVSTFVRAVQQGRFDR

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Crispr_ID: NZ_CP040605_21

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_21

5649687-5649784

Orphan

Consensus_repeat	Method
TGGTTCGGAGTTGCGGGCGGCGGTCAACGACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040605_21

>merge|NZ_CP040605|21|5649687-5649784|CRISPRCasFinder
TGGTTCGGAGTTGCGGGCGGCGGTCAACGACTTCCACCGTGATCGCGGCAGGCAGGTGGAGGCGCGTGGTTCGGAGTTGCGGACGGCGGTCAACGACT

>NZ_CP040605|21|20|5649687-5649784|CRISPRCasFinder
TGGTTCGGAGTTGCGGGCGGCGGTCAACGACT	TCCACCGTGATCGCGGCAGGCAGGTGGAGGCGCG
TGGTTCGGAGTTGCGGACGGCGGTCAACGACT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168588071.1\|5624062_5624701_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373064
NZ_CP040605.1\|WP_168588081.1\|5655502_5656759_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168588077.1\|5630095_5633440_+\|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|239160
NZ_CP040605.1\|WP_168590367.1\|5633708_5634983_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379730
NZ_CP040605.1\|WP_168588072.1\|5625628_5625796_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168588076.1\|5628582_5629956_+\|phenylacetate--CoA-ligase-family-protein	unknown	unknown	gnl\|CDD\|274074
NZ_CP040605.1\|WP_168588083.1\|5669058_5670090_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168588075.1\|5627911_5628577_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|188483
NZ_CP040605.1\|WP_168588073.1\|5625782_5626289_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|315923
NZ_CP040605.1\|WP_168588074.1\|5626231_5626444_-\|winged-helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379282
NZ_CP040605.1\|WP_168590368.1\|5672391_5674242_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NZ_CP040605.1\|WP_168588078.1\|5635270_5644372_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223496
NZ_CP040605.1\|WP_168588082.1\|5658834_5668980_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274009
NZ_CP040605.1\|WP_168588084.1\|5670686_5671520_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|252734
NZ_CP040605.1\|WP_168588085.1\|5674530_5675889_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|365860
NZ_CP040605.1\|WP_168584616.1\|5622528_5623365_+\|transposase-family-protein	unknown	unknown	gnl\|CDD\|372577
NZ_CP040605.1\|WP_168588088.1\|5678492_5678666_-\|DUF397-domain-containing-protein	unknown	unknown	gnl\|CDD\|377231
NZ_CP040605.1\|WP_168588087.1\|5678240_5678414_-\|DUF397-domain-containing-protein	unknown	unknown	gnl\|CDD\|377231
NZ_CP040605.1\|WP_168588080.1\|5651798_5655542_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274009
NZ_CP040605.1\|WP_168588086.1\|5675899_5677939_+\|NADH:flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240085

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168588071.1\|5624062_5624701_+\|hypothetical-protein	gnl\|CDD\|373064	pfam14430, Imm1, Immunity protein Imm1. A predicted immunity protein, with an alpha+beta fold and a conserved C-terminal tryptophan residue. The protein is present in a wide range of bacteria in polymorphic toxin systems as an immediate gene neighbor of the toxin gene.	6.48968e-05
NZ_CP040605.1\|WP_168588077.1\|5630095_5633440_+\|molybdopterin-dependent-oxidoreductase	gnl\|CDD\|239160	cd02759, MopB_Acetylene-hydratase, The MopB_Acetylene-hydratase CD contains acetylene hydratase (Ahy) and other related proteins. The acetylene hydratase of Pelobacter acetylenicus is a tungsten iron-sulfur protein involved in the fermentation of acetylene to ethanol and acetate. Members of this CD belong to the molybdopterin_binding (MopB) superfamily of proteins.	1.64659e-91
NZ_CP040605.1\|WP_168590367.1\|5633708_5634983_+\|hypothetical-protein	gnl\|CDD\|379730	pfam15567, Imm35, Immunity protein 35. A predicted immunity protein with an alpha+beta fold and a conserved tryptophan residue. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, usually containing a protease domain such as Tox-PL1 and Ntox40. In some instances, it is also fused to a papain-like toxin, ADP-ribosyl glycohydrolase and a S8-like peptidase. Based on these associations the domain is likely to be a protease inhibitor.	8.58851e-19
NZ_CP040605.1\|WP_168588076.1\|5628582_5629956_+\|phenylacetate--CoA-ligase-family-protein	gnl\|CDD\|274074	TIGR02304, conserved_hypothetical_protein, putative adenylate-forming enzyme. Members of this family form a distinct clade within a larger family of proteins that also includes coenzyme F390 synthetase, an enzyme known in Methanobacterium thermoautotrophicum and a few other methanogenic archaea. That enzyme adenylates coenzyme F420 to F390, a reversible process, during oxygen stress. Other informative homologies include domains of the non-ribosomal peptide synthetases involved in activation by adenylation. The family defined by this model is likely to be of an adenylate-forming enzyme related to but distinct from coenzyme F390 synthetase.	2.58311e-30
NZ_CP040605.1\|WP_168588075.1\|5627911_5628577_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	3.59278e-19
NZ_CP040605.1\|WP_168588073.1\|5625782_5626289_-\|hypothetical-protein	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.93763e-18
NZ_CP040605.1\|WP_168588074.1\|5626231_5626444_-\|winged-helix-turn-helix-domain-containing-protein	gnl\|CDD\|379282	pfam13592, HTH_33, Winged helix-turn helix. This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.	4.79709e-13
NZ_CP040605.1\|WP_168590368.1\|5672391_5674242_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	3.43658e-35
NZ_CP040605.1\|WP_168588078.1\|5635270_5644372_+\|hypothetical-protein	gnl\|CDD\|223496	COG0419, SbcC, ATPase involved in DNA repair [DNA replication, recombination, and repair].	2.7316e-13
NZ_CP040605.1\|WP_168588082.1\|5658834_5668980_+\|hypothetical-protein	gnl\|CDD\|274009	TIGR02169, chromosome_segregation_protein_related_ptotein, chromosome segregation protein SMC, primarily archaeal type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	2.34826e-14
NZ_CP040605.1\|WP_168588084.1\|5670686_5671520_-\|hypothetical-protein	gnl\|CDD\|252734	pfam04672, Methyltransf_19, S-adenosyl methyltransferase. This family contains a SAM (S-adenosyl methyltransferase) domain, with a central beta sheet with 3 alpha-helices on both sides. Crystal packing analysis of the structure Structure 3giw suggests that a monomer is the solution state oligomeric form. An unidentified ligand (UNL, cyan) was found at the putative active site surrounded by the residues His57, His170, Phe171, Tyr216 and Met22. The UNL is likely to be a phenylalanine or phenylalanine-like molecule. (details derived from TOPSAN).	9.6299e-95
NZ_CP040605.1\|WP_168588085.1\|5674530_5675889_+\|MFS-transporter	gnl\|CDD\|365860	pfam00083, Sugar_tr, Sugar (and other) transporter.	1.20054e-43
NZ_CP040605.1\|WP_168584616.1\|5622528_5623365_+\|transposase-family-protein	gnl\|CDD\|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.95997e-24
NZ_CP040605.1\|WP_168588088.1\|5678492_5678666_-\|DUF397-domain-containing-protein	gnl\|CDD\|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	5.09896e-16
NZ_CP040605.1\|WP_168588087.1\|5678240_5678414_-\|DUF397-domain-containing-protein	gnl\|CDD\|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	1.31648e-15
NZ_CP040605.1\|WP_168588080.1\|5651798_5655542_+\|hypothetical-protein	gnl\|CDD\|274009	TIGR02169, chromosome_segregation_protein_related_ptotein, chromosome segregation protein SMC, primarily archaeal type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	9.06884e-10
NZ_CP040605.1\|WP_168588086.1\|5675899_5677939_+\|NADH:flavin-oxidoreductase	gnl\|CDD\|240085	cd04734, OYE_like_3_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 3. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase. One member of this subgroup, the Sinorhizobium meliloti stachydrine utilization protein stcD, has been idenified as a putative N-methylproline demethylase.	9.56665e-168

>NZ_CP040605.1|WP_168588078.1|5635270_5644372_+|hypothetical-protein
MFSSIMVPEGVRRLFQVLTGEDMTDADEGALFAVADVLESGAAGLGEVRALVAELVGKVRTEFSGKAADRFADGLGIFDGLLSSGQAGLLDLAAFVRKTSQQVRYLKLVTIYGLELLAVEMSWAMQFAGATAGATLAWLAARMAVMRFLLTSWWRQLFMRLAMMAAGGVVFNVLPDVQAQLTMRGEESAEKWDRTLTEQAAGMGAFSALVALPMSAVGGLVSNTLTKVLVKGLGDDVDAAILEAAAKKAVAEHAELYPVSAMAKFADAVGKSLDNYAGMSVGAMWLARFGHSVGEALAGSLSEFFGEALYAAATGQKVTWNPFSLTAGFFETVFSGVGNLAGLALRGKLHPEGPSPYLEGTGGGGGGSDDGGGSGGEKTPLPGAGSGSQTGDIPGSPDKDSVFIPSDASDSSDGSRSDRWAGSDSGAGSDSSSVSDVDSVFSDTGSVDSAAVSVPSGDGLVVPGSAVVSAVVVGGTDGKDGTDGTDGKRGADGSVPGRDAAGDVPVVPGSGQHRPGTPPPAYSSGVPGVDPDRPGTPLPAHFGGVPGVGPDRPGTPPPPYSPGPGGDQAVPGKRPLEVSASKTPDSPTVTPHASDVPADAARPETGKPGSVVGPDGRVPAGHPASETVGSGSAADSGSGVSGGHPESPSGVTGRDGDPGADSVAGRGDAHRQDGAVVSPDSATLPGEGSPAAPSLHRDPAAVLPAGLPADTVRVPVPANVVAGDRLGLAEFVRSHGADSPGGPVLLVSPSDPNAGVVVTRGQGLALARDLGRNVVAMMPGQAGREPQFMVFPADRSRPKSLAGPGAAVLAGGRSGGVAGLADASATVPAASGGKTRGEAPAAGTGSAQARSVAGEVQPASTTPGAGAGMVRDTSGIPVGQWTQEELVRAIARARELGLSSDEKDAAAQIVWLAHDVQVLARGDAVVPLEDVVALVAAKYHDLGKDHRDQVVKFSRALADWLGTRRSKPVIHAGAGPEGHTADGGPSGSSSAAVPRNVEGHRRRAETATAKRRTKIAELEDLLKPLRDEQASLEASLGRDEADAGSRTRGEELQGRIARWQAVLDGLKTKDQQVRARGAERTNKWRERQQRKSRAARLGAGGPSPAGRSDQIAGRSEEPSAAAELSELITNANAGLDSMRQQELPVDQLIDAVKPHMESFGGHDGLRDVMAHHMLRYPGDSEETRKFERKLHKLTTVRNWDEWYERDATRLDKWAGIVGRDAVDRLLADADMVLGSLRVSLRFRTVLAQWLGEHPGDRRGAQAVRGIMAGYLAGDPDLGVAVSGLTLDEFETAKAEEARWQEDRAANPAEAAAPMVRGFADDPALDVISRISSIQHKFEDVGQELRQWARTEDQDAVDLLYDQADQVLGPLKESEPFRDVMAHELLMRRNNLRDDQQLQRFMTNPQDDPQLRQLRWELARYLAGDLTGGADPDTADNLLSAGMGPLPEDIRSRGKLMYNRRLTIGKALSGLQDDAVNEVLRNAALEDLRRGKYSHDTLGKRFYRSGPWGGTVFVIRDLQDAVGSLRQVLAEAETNTDRRDEYEPKIAEWLNLRGFLDPTAIRSRATEVADAVRLLRQENANREPTQDGRMLPVFDNGEGTGQWYLRSRDGELEARGSELRTAVNDSAVPTDPEGAPPAPVFRWAGTPGPSRTRTAGNEERKARGRERWHREKAVEAARVAELEAFLKRANSGQDSWAASQESDAANPRQRGDLQREVRDAQAELKKIADDRTAKKAKHAADQKSSEERKRRVVADARASLAAARAGRAELEELPGFDREDRRRWEALQREEAAALEVLHDHELMRDQVAVRKRKLEDRYKDEWAQESKSLRELMARQAKLEVLTARDETETRGEELAELEGLPGRIAEVQAKLPGIAKLEAERKANHAEKEKKNKARRKANTLLATFRTRREELVESDAVQGPEWEEVQGSIAALEAELAAIANDDMGSGATARGNGGADREMPAGVVELVGLVGRVEGHLSVLPAGFRRDLHDQVEEAWAMAKKGSWIRGDPARIDSQLERMRDLERWLGEVVRSPGVVELEGLVGRVEGHLSMVPADVLLDVRAGVVKAKAMARQGSWTPKDRAWIDSKLAGMRKGERWLAEVVSSPGVVEFVGLVERLEGHLSVLPADFRPDVRAGVVQARVMARKGNWTREDLSLIDSELGRMRKLERWLRLEPVVFGVDPGVVKLASGLRGVQVVGVHVTPDGQAQSADDVLETPEDFAARVLSDERFVPGVPVAFLGCGALRQPPGGEDSFAKRFEDASGVKLMLATEADVWHTDDGLIHATETAVTQDGRIFPVFDNNKGTGYWSLRNRGREVGALGSELRTAVNDFHRDRGRQVEARGSELRTAVNDSAVPRHPEGAHSAPVFKWAGTPGPSRTSRTAENEEKKASTTEWRHRKKAEEAALVADGRALLEKLTTRQAELKALPGLDEEQTEEWNALLGRIAEVQANVAAVEQKGADRRARDAASERRRYERTKREKNGLVDARKVLLEQLMVQRAPLAVLAELTVLDTNQRAELEELDASIEEVRNELATIANEEQARKAQHAERMRKQRARKKRGQADALASLAAARAGRAKLKELPGFTEVLQADPATLPEFYKEPRRQWEALQREEAAALELLHEHERMRNQGVARMRKSEDRYKDEWAQESKSLRELMARQAQLETLMARNETRGEELAELAGLPGRIAEVQAKLPAIAKLEAERKANNAENDKKNRARKKANTLLATLKAQRAKLVESDSVQGPEWEEVQGSIAALEAELAAIENDDTGSGATARGNGGADREAPAGVVELVGLVGRVEGHLSVLPAGFRPDLHGHVEEAWAMAKKGSWTPADRARIDSQLAGMRELERWLGAVVRSPGVVELVGLVGRVEGHLSMVPADVLLDVRAGVVKAKAMARQGSWTPEDRAWIDSKLAGMRKGERWLAEVVSSPEVVEFVGLVERLEGHLSVLPADFRPDVRAGVVQAKAMAQKGNWTPEELSLIASNLGRMRKFERWLRLEPVVFGGEMMISGWLRGRWSWPAVCGVCRWWVCM
>NZ_CP040605.1|WP_168590367.1|5633708_5634983_+|hypothetical-protein
MNELAERARTWLHDTYGQRVVLRDEEAILSTERVAFFGCRYVESDEPMLAATICVPRDGADPFPASNAGPLDEALNVSRSEPRAWRWRVNARNCVIATDAAVNCWPASALPWDPAGETPGWWDRMLAAYFPDAEVLICSTWADASRAIVDGGVGTRAVVWLRRQLGGRELAGHLLYADYADDAVVFLDGLRGTVAEQNDAEVAELVVARFRRRQDESVGGLLPSEAAADEFAGAVEKAQAWLAYRYDGEVELVGPDPADETERGWLFACTTRSFQRSGDWRDQMLDAAVVVPKAAGEQPFGLPNRDPWTWLDDWNAGKPGLMPPPEPAQAAWFGPMVAELGPVVGSSVHEHWFGVLEEIASFPARTQALVWLRRRDPRGRESVGHLLVAVNETEGVQLFDPMDGRAQPLIETVPFEFRVMRFDS
>NZ_CP040605.1|WP_168588077.1|5630095_5633440_+|molybdopterin-dependent-oxidoreductase
MSEEVRGFCTLCRSRCGAVYTVDAGALTSVRPDPEHPTGAALCPKGRAAPEIVRSPRRLTQPLRRTRPKTEPDPGWQAIGWDEAMREIAEQLARIRDASGPEAVAFAVTSPSATPMSDSIDWVERFIRLFGSPNICYATEICNWHKDFAHAFTFGCALPTPDYAGADLAVLWGHNPAKSWLAQSAALAEARARGTSVAVVDPRRSTSALQADHWLRVLPGTDAALALGLANELIRTKAYDEGFVREWSNGPLLVRTDNGRFLRAEELDPELDGFVVWDEEIGSAVTYDTQRAAAHPERFALLGRRRVATRHGDVECVPAFERYAAACAAWPLERTSATTGVEVRALHEFARDLANAGSVAYYGWTGVGQHANATQTDRAIATLYSLTGSFDAPGGNVVLPKLPVNQVTTPGQLTAEQREKALGASEFPLGPPTQGWVSARALCESVLSGQPYRVRALVGFGSNLLVSQPNPGRTAEALRSLEFQVHLDLFANPTADFADIVLPVNSPWEREAIRAGFDITQRAQEHVQLRPRLVEPVGQSRSDTDVVFDLAQRLGMGEQFFDGDITAAWNHQLAPLGVTVDELRRRPGGMQIPLDTRYRKYADVGDDGQVLGFGTPTRRVEMYSEQLADHGYSPVPEHVTPPGTDTAPLVLTCAKNGYFCHSQHRGISSLRKRSPEPVVDISPQAAAERVISDGQWVSIVTDNGTVRMRARIDPALHPRVVVAEYGWWQDAPDLGLPGSDPLQQGGHNYNLLISDDVHDPISGSIPMRSFGCDVRPEPTAAWPGLRSFTVADIAAETDGVRALRLRPSDGGVLPDFRPGQHITLNHLDTTRSYSLIGAARVDERDAYTVAVRHVPDGDFSTFVHERLRPGAEVSVAAPAGSFVIPAEIDLPVVLLAAGIGITPFLSYLETLAATGGTVPKVVLHFGNRNQHSHPFGDRIRELQRAIPQLTVIDHYSRPAGEGSAFRSGRLHAGQVDAELIRQRARFYLCGPEEMLRDLSTGLVARGVPRFEIFAEKFHAAAREVAIPDDAAAEVHFARTGKTLRWRKADGPLLQFAEDGGIPLPSGCRLGQCESCAVTVLNGRVAHLVAPTDDLSEDACLTCQAVPVSDLTLDA
>NZ_CP040605.1|WP_168588076.1|5628582_5629956_+|phenylacetate--CoA-ligase-family-protein
MGDSVRELARDARQAVREGPVGIARHQRAHLTDLVAHARANSPYYRELYRDLPDGVDDPTVLPVTSKKELMARFDDWVTDREVTREKAEAFVADPDAVGKRFLDKYLVATTSGTSGLRGLFLLDERSMNMEGALGTRASGVLGAGDAIRMLARGGRTAIVTAPGGHFFTVAGTARFQRDHPRLGRRLRVFSIHRPLPELVEELNRFNPAVLSGFLGMLTLLAGEQEAGRLRIRPALIIPGGETLTTGLGKRLATAFGAKVRAAYAATECSFLSMGCAHGWYHVSSDWAVLEPVDADYRPTPPGELSHTVLLSNLANRVQPFLRYDLGDSILLRPDPCPCGSVFPAIQVQGRAADLLTFPAEDGEPVTMSPMLFGTVLDRVTGIGQYQVVQTASSTLRVRLRPADSAAAEQVWQTVRGEITHLLKEHEVADVTLERADEAPQQEPGGKFRRIIPQTKP
>NZ_CP040605.1|WP_168588075.1|5627911_5628577_+|TetR-family-transcriptional-regulator
MYVRGVEESRRERKKRLTRQRIVLAAIRLFDKQGYEETTVTQVAEAADVDPKTFFNYFRTKDEVLFNELDLEFDVLLAAIRDRRSEESPGEVLRRAVQEYAAHRRPNVPRREPAEVSAAARLALTTPALQAKGAYLLLDLQQRIAAELLNAFPGELDPVTAAAMTGSVLGAIQQASLASAKLGRSQQELWEAAEHALDIATNGLLSVRPRTRDQKQTEERI
>NZ_CP040605.1|WP_168588074.1|5626231_5626444_-|winged-helix-turn-helix-domain-containing-protein
MWTRKAVAELIRVRHGVVLSLRTVGDSLRCWGVSPQRPIRRAYERDPEAVCWWLEEAIRPSPPAPAARAR
>NZ_CP040605.1|WP_168588073.1|5625782_5626289_-|hypothetical-protein
MAGGGYPAIAARARREGAVILWLDQTGIRSDAAVGRTWAPAARTPVVGKTGETVQRDHLDRQVQVIVDGHPVHRRKTVRKWVDDHAAAIEMHFLPGYNPELNPDEIRGADLKRTMSTGTAQKIRDESKQAVRSFLHRLHKSPDQVRSYLGKPDVRYARLTSHNCPTNQ
>NZ_CP040605.1|WP_168588072.1|5625628_5625796_+|hypothetical-protein
MEEQELLVISVRQRSVVQDRLNLVHGDPSKSGGGDGHGEQGGDGLNIPEWPVIDS
>NZ_CP040605.1|WP_168588071.1|5624062_5624701_+|hypothetical-protein
MTVHGTTTTAGRSPRSTGGKHERFWADVLNDQEVLLTPTMDIEEIIRGLAEHDQECQRPEAGLAWFLLHEPDEDAPTLTLGVRGTIGSLMWFDATSALVPADGTNAGYVGYFTMDGHMMVMSPHAELPIARVHEALREFARTQQLPSPCCFGTGWQVSTVLPRGDVAVRAGFSELAGVGGYHFVGGTPSEATVGHGGGDQEFGQVVADGRRR
>NZ_CP040605.1|WP_168584616.1|5622528_5623365_+|transposase-family-protein
MVTYSAKLDVPRELVVFLSRLLAGERRRKGTRKGRRALTTFWQAVLVLRWFRDDTDITKLARDHGVARATGYRYVDEGIKALAAQAPDLHDALQRAKDNGDAYLILDGKNFSSDRLGEKTTSAKGAEIDLWYSGKTREQAGNIQALTDPDGFPLWASDVEPGSIHDITAAENHVLGALYWAYSQLNLPTLADGGYQGAGAGVLTPIKRPKTSKGRPLDVDNQTYNKLLRGLRALGERGFALLTGRWRVLRHFTTSPRKIGLIVKAALVLTQFEHGRLA
>NZ_CP040605.1|WP_168588080.1|5651798_5655542_+|hypothetical-protein
MTPDGQAQSADDVLETPEDFAARVLSDERFVPGVPVAFLGCGALRQPPGGEDSFAKRFEDASGVKLMLATEADVWHTDDGLIHATETAVTQDGRIFPVFDNNKGTGYWSLRNRGREVGALGSELRTAVNDFHRDRGRQVEARGSELRTAVNDTPVPRHPEGAPPAPVFKWAGTPGPSRSRTAENEEGNARGRTRWARDKEKQAALVADGRALLEQLTTRQAELKALPGLDAEQAEEWNALPGRIAEVQANVAAVEQKEADRKARNLASHKRKYGRTKRETNELVELLEQLMVQRAPLAVLAELTVLDTDQRAELEEWDASIEEVRNELATIANEEQDRKEKNAERMRKQRARKKRGQADARASLAAAEAGRAKLEELPGFTEVLQADPATLPDFYKEPRRQWEALQREEAAALEVLHDHERMRDQVAVRKRKFRDRYKDEWAQESKSLRELMARQAQLETLTARDETRGEELAELAGLPGRIAEVQAKLSAIAKLEAERKANNAEKVKKHRARKKANTSLATLRTQRAKLVESVDVHGEEWEKVQGSIEAVEAELAAIENDDTGSGATARGNGGADREPPAGVVELVGLVGRVEGHLSVLPTGFRPDLHGHVEEAWAMAEQGSWTPEDRAWIDSQLERMRDLERWLGEVVRSPGVVELEGLVGRVEGHLSMVPADVLLDVRAGVVKAKAMARQGSWTPKDRAWIDSKLAGMRKGEQWLAEVVSSPGVVEFVGLVERLEGHLSVLSAGFRPDVRAGVVQAKAMAKKGNWTPEELSLIASNLGRMRKLERWLRLEPVVFGVHPDVVKLASGLRGVQVVGVHVTPDDGQAELAAGVSETPEDFAERVLGDERFVPGVPVAFLGCGALRQPPGGEGSFAKRFEDASGVELMLATEADVWQTADGLIHATETVVTQDGRIFPVFDNNKGTGYWSLRNRGTEVGALGSELRTAVNDFHRYRGRQVDARGSELRTAVNDSAVPRHPEGAPPAPVYKWAGTRGRSRTIRPAKNEERNEKERARRARNKEEEKKEAARVAELEAFVERANSGQASLAASQEPDATEPRQWGELQREVQDAQAELKKIADDRTARRAKRAGYQKSYEERKKRKVADAEELLAAARAGRTKLEELPGFTAVLEANPVRLPESLKKSRSKWEALLEDEAASQEVLQKHERTRNQRNARNTRSNKRYQDEWAQESQSLRELMARQAELEALTARNETRGRSWRSWRSCRGVSRRCKQSCPRLRNWRRSGR
>NZ_CP040605.1|WP_168588081.1|5655502_5656759_+|hypothetical-protein
MPAIAKLEAERKVKNAEIEKKNKARMKANTLLATLMTQRAKLEESGAVPGTEWEKVEGSIAAVEAELAAIENDDMGSGATARGNEGADREAPAGVVELVGLVGRVEGHLSLFPEDFRPDLHDQVEKAWAMAKKGSWTRGDPPRIDSKLAGIRELERWLSEVVRSPGVVELVGLVGRLEGHLSKLPAGFRPDVRAMVAQARAMAQQGSWTPEDRRLAGMRKVERWLAEVVSSPGVVEFVGLVGRLEGHLSKLPAGFRPDVRAGVAQAKAMAQKGNWTPEELLLINSQLERMRERERWLDEVVRSSGVVELGGLVERVEGHLSVLPADVLLDVRAMVVQARAMAQQGSWTPEDRRLAGMRKVERWLAEVVSSPGVVEFVGLVERLEGHLSVLSAGFRPDVRAGVVQARAMAQKGNWTRRS
>NZ_CP040605.1|WP_168588082.1|5658834_5668980_+|hypothetical-protein
MPTPSADDARAETDEDMQSEFDEDYNVRDSDEQRSEVPERFPSSVSGQVLGAGVEEIPAGIMVSPSDLGEDLVAVARALPVEDGVLAVVAKGDGHGGVLLGGKSVDAQRLASLIQGGLRGKRKIRLYACEVSEEFATALDGASGVEVIWTRGLVWFGPDTKGFSSMVGGWYLDEYFTLRPDLTEEVPWVTTRPEAWPPGQSPSDVSLPPGRRGLSPRWVHLRAETARFRTGPQPDLAWLRESGQTAKVVQARSAITAADDRLTQVYSMVDAPVPEEPATTVTAAGSAETDVLVKAATDVTTSAAASVERAARQAGKWTAAQQELTAATQRQGEVRAELKAAAQDLGAAQKDLVQKQAEERVARERVKLLGNEDEDQGVVREKLRAQHAAAAARVKTAEAALTAVQERVDRLARADREAGEHIAVAVARVESERGFTVDAARTATKAVAQARIAADRADVTVRQVDLPSYTGDGAMGSGKIWRPGEIDPEQVLAALPVGVREGARAVVEELFSEAKIGDTLRRLADEGIRVEVDSRELHVKFERTAATPVQVPKGEGFTEWGIRSADASRTITREGGPQYSLPAGIPNMLGAATEGVARSWLLHPSVRPSWGTNEQRNLVSTTEFSRGINSRPAERHSIQVPERHFVVDGRFVIDVRVGEEPPRTYRSDVIRDVALVRFYGEDVPPATINPGPGGPVLPVPASALHEVFVVPQAAAVRRIRQRVLAGLPLPKVGVEVRDAVSRELAEDAAIVKFGEITGGGYRSSPLRLPGATLNTLSLEVSAALRSVRRVDDRVVPDVNLRQIAGGDTKSDTSVAQSASAEASASVGPALVTELKEQRRGLGAYTVITPFTVSGAAESGETLTQVVGTSSGKKTVASIEGDSVLVEATLDMRVQRYSTDPALEGSDTVAEKVFLWMPVEEFARLEEISAAHSALRVAEEHDGPHEPPAVPERLRQSQNFRDLVDRVRPEVTRTPAETETEAVTEAVTEAVTEAVTEAVTEAEAVTEAEAGGGDARLGNDRAEQLALSILADYGKRPEITIPVGGRRQPDMLAAGKSTGGGVVDRAPGIERVLPEVRRLLRESVGEELASLDHDLRSVVESLLSSAFGAPGLFREFSGELRGATETIRVGDRLVTIEVRPRLGALVGTGRVEKANVDVTARNAIRGEGKAKAGTKQRIGVESGATVGTKRKDFWRTLGFLATGSVQFSHSYTGTVGQSHKVHRRARFVGPAVTFDRRVTWSISVSTKTIPAETGQPEPSQTGQPEPQAGQPEPSQAGQQGSQAGQSGSWYRGLGLLGGWGRRSDEADSGGIELDTLSGDTVTAGSDSDSVGSFGGASASSSATTVSGSTVDGWTRVLVPEPLAPITEQGDLRNLGTVIRDFDYDDQDGNPFQVHVEFVMPQGVATPSTVLGEPIEAILEDRAGGQRQDLTTAGENSPDSLEAQFDQLVSPGGVVIAGSRVRLRLFDVHPVGTAAKKLNLEVGTEGGLKLDGQEMRGRGFEGRLRGSAWMLFGGKSSRAYVAPSLTGRGRFGEEEGATFGRGTQRRRVGRTTGATHLYRAHGVFEITSYGESGAAGSTETVVVGGGVEFLLSDIVAQRLRTHPVREPAAQGRPPRTRHLELPAGVEPKPAPVTEVRYPPEFVFSGAALGPTLVTEISNAHEVAPLIKSMISEHAPGFRSGRWLEVPTGIAGSVDTLASVNALAARFGQEATSGVPLLAARPYRGGTETIEFVIRARYAPDAVATPDKDTKSDTSFLHSEKRVHTVARSRAVGGGASVLVAGKGRGNLRRGGAHPQVGYDNESSRIQRDSESDTFKSRVLGTEAISYSYTWPTWFQVEMYRTWTPNAMLNTLLLNKPRQGIEMWAAMREDTRTPLQRGFTSEGTARYIIPGGLTTTTPPLPRPVRIGGRLVPAGGAQRLGPLPQDLRGVDVIPLALPGSERLFPWLAAVLAHPAPEPADDADPQTSEGSMRAPAGNGWVRPATLPAQMLWQLGGEEGLTAMMPDLLADPVVFPAMVETGMVWDDEHGLAVRLRFTGIEYVDSFTATGELTQEQKTEQELVQSEGGKTSAAVIGQATVDSGGPGASGEHGKLTGDMLFPGETSTLDPSVGLSATWSDPRVQKFTGGTTREVTTERRGLYHVYRAAEAVYTITGLTKRRVFSAALPGKTAEVEVTITNGGYFAVESTQAAAKNLPGPPPKPTTPATAPAPAAALGPAALPAVWTPHTGDEHAAGLLPKIRGHLVVGLTASGGTLTVPELAARIEQLPGWARRPIVLVGTDGSFDLADAARLRDTLGVDVIAADHEVWHAADGRVVTGNLSFVRGGAPTWSERAEAILGGEVRSATAGHWHLLSAAGGTRRLPGADLVAALASTGTPAQAGTAPRSDFRWGARSAPVALAIHGATDTADYTTWTRSPYHAAARPEGSKPLLVLGHDDTIIPNTEVTTLRDHTGADVLARVNRGRGPKWMLHRADGSRPRPVDPPTEVTPTPRPQPLLFAGPEDSPATIAQAARSAPHLPADIQPVGVHVTPDGLAVLPDDRKVTPEAFADEVRQHPRFVPGLTIALLGCAANRPPEPGQPTFAQRFARALRTWVWTTTDDVVQTTDKRVHATQVTVAGDGTLLPQFKNGQGTGHWDLLDPEGQPLRTAGPDLAAAVTPDGTAPPRYPEGTHPTPVIRWTGRNGKRSYVKTAEQKEKYSATERQRYAADPSFREKKAQVRRDRTVLLRERDELVLGAEVLLGAAQARLAALPVGDGARQAVLGRIGDLQGVLDDLRKETSAQILRDEEAARASAAQTEEEREQRRKETKTENQRLRRGRLSAAQREKERERAREYDKRYRAGLGDAQREDQQRNNREMTRLKRERDKLIDEAEKLLGEAEARLAEVEARLAALPWSDKTRQEELERARQEELRCIEDLQGVLDDLRKEEIPVIRRKEAELWAIEEDSGSSDVASVGGRVAASVPDAAQMTESGAREKAASDEQARASLADWVAQVRASLKGIKSRQDWFALQDRDFVLQWGQELPTLDEAMRDEREELQRQLDEITGDVVVELKRLVGLLDGHLAALPADSLPKVRAQFALAKAAAEQGSWPLEQVYKIASKLGGMLEMEQSLRNYRLGLARDGDSRRAIDEGGARTAQDGSRPWPVDPPIEVTHPPRPQPLLFAGPGDSAETIAQAERSAPDLPGTQPVGVHVTPDGLAVLPDGRKVTPEAFADEVRQDPRFVPGLTIALLGCAANRELEPGELTFAQRFARALRTWVWTTTDDVVQTKDKRVHATQVTVTGDGTLLPRFENGLGTGHWDLLGSEGESLWTAGPDLGAAVTLGGSAPPRYPDGTHPTPVIRWTGRPKLTDEQRQRKTANQRLRRGRLSDAPSAQPDDTAPDAMDRNP
>NZ_CP040605.1|WP_168588083.1|5669058_5670090_+|hypothetical-protein
MTTPDQKADVRAALHEVLLRQAGFAPDELVTQARAWLADDRFDEVARAVVSTVARYVLPLTVEDLDVLVTVSEAEGVSLDVLESIEPTIDDPPLVWRFSAQPPDSVDSTDDSAVAALIDVLGEEPAAHGMWRAWRMVPDGAPYPPPRPVYVVEADDDDLPALTARLQEALVAAGEAAPQVEVTPAVGPVPTYQQAARAYGALLWAATEAPEITVARVFDAVDPISGPSFAPDHPRMDNEAERGQILDYLRAGTALMITTATLEDVVDPTRGAVVPMSFRTDGTWIWPDTIAYYLEHHHLAPDPDLLAHIRDAGLLPPELDTVAIHRAMDVLRRPPETEPVWTR
>NZ_CP040605.1|WP_168588084.1|5670686_5671520_-|hypothetical-protein
MKRPSWAPLDVDMNQPSIARIWDWFLGGAHNFAVDRQVAEEMLQLMPEGPQMAHINRMFLRRVVQLCVAEGVTQFLDIGSGIPTVGNVHETAQQADPECRVVYVDIDPVAVAHTRRLLADNPRCAVIQADLREPEEILAAPELRDLLDLDRPVALLMIAVLHFVHDEEDPLGLIARYRDALAGGSFFAIAHGSRSTERMPSEHLYAARSKYERSVAQVSLRSQPEVEAMFAGFDLVSPSVVWLPVWRPANGETPEDSAAPNAGYGGVGRKPRTNRPQ
>NZ_CP040605.1|WP_168590368.1|5672391_5674242_-|GntR-family-transcriptional-regulator
MVGRPRNAVVLTDTERAALLKWTRSRTCSRALALRAQIVLCCEHERTNTAVAQSLGISRGVVGKWRSRFLDQRLDGLHEQPRPGRPRAVDDDAVATVLIRTLAPAPGARHAWSTRSMAAETGLSQTTVNRIWRAHRIHPAAGSSPRRADQASLLPAEIHDVVGLFLDPPVRVLAVSATPHRTPLRDRRPAGRGADRRSAETRNLFAVANAFASLRGMTAGMSGEGVPLRAFLGHLDRTVAASMNVHLLAGGLDEPALRTVDEWLHSQPRFRCHSAPDQSSWIDEIDFLLANNPLPGHENLFGFAASLTKVRNDVRAWCRTWTPRTSPYSWAKSPRALWSGDAANRRLNNDSKSASETTPEQPGRDLEPTSAIPDDPATASGTTDRVVHLVREALAAGQYHAGERVKEAPLAARLGVSRGPIREALRILAEEGTLERLPNRGAAVPDVSATNILDLYAVRASLGALVMRRVAVLGQAHLQPVNTALAEVRAAARNSDDVRIGEADLCFQDAIARTANLPQASSFFERLTMRLRMFISVLRLGYAEAGDLIARENAAIFDALRNGDGNEAARLWRVKVERSVRYMVAQLPRDHFDPDLWITIAGKPNPRPSDPRNLPR
>NZ_CP040605.1|WP_168588085.1|5674530_5675889_+|MFS-transporter
MSSSIIDDQPYGRFHRKLFFLSAGGPFLDGYILSVIGVAITGATRELGLTSFAEGLVGAAALVGVLLGGFVFGWVTDRVGRQVMYTIDLIALVAASALSLFVTEAWQLVLLRFVAGVAVGADYPIATSLLAEWLPAHRRGRTMGALVAAWFVGASASYAVGYLVAAAGGEDLWRWVLASAAVPGLIILLARIGTPESPRWLLRHDRPQDAAEAIRTALGRYPTEQELARLAETEPAKSSRLSDVFTGGYLRRTLFVGGFWLCQVAPAFAIWTFYPVILGAYGFEAGDTALLWSMVVSLVTLAGCVPCIRWVETYGRRPVIIWTFVGVTVSLAALGSFPGMAAALAILMFVVNALAQGGGNILQWIYPTELFPTDIRASAVGVASAISRIGAAAGTYLLPVGLEAIGLGPTMLVGAGLSVIGTAMCVAWAPETKGQALHESAAVPQQSEARAG
>NZ_CP040605.1|WP_168588086.1|5675899_5677939_+|NADH:flavin-oxidoreductase
MSVTRDPLLTPFRIKNLVLRNRIVSTSHEPGYGEDGMPTERYRAYHVEKARGGVGLTMIGGSSVVSVDSPPSFGNLHLYSDEIVPWLRQLSDEVHAEGAAVMCQITHLGHRTSNYTESWLPTVSVGNLREPAHRAFTKQAEIADLERIAADYAAAAARCEAGGLDGIEIQAYGHLLDSFWSPALNNRTDDFGGSFDNRMRFPLQVIAAIRAAVSDEFVVGIRMAVDEQLPGGVDEDEGLAIAAVVVDAGIDFISVIRGHIATESGLSDVIPPMGEASAPHLDLAARVKRKIDVPIMHAAKIADVATARHAIDEGLLDLVGMTRALMADPHLVAKIEAGQEERIRPCVGASLCIDAAYIGEPAYCIHNPSTGRELRLPHRISAAPQAKNAVVVGAGPAGLEAARVLAERGHHVTVFEAAPEPGGQLRLASRVQRRRDLIGIVDWRVAECTRAGVRFKFNHLVEADELRGLAPEVMIIATGGVPNTDFLDFGADLVHDTWDIISGAVLPTGSVLVYDDHGGHPGLDVVELLAGSVAQVEWASPERTVAVDVGSVNAPPYLRTMLNHDVRISLMHRLVGVQRDGDALLATFTSDPTRRSFTRRFDHVVVEHGTLPNAELYEQLKPHSTNEGEIDYAKLLDRSPQDRLRNEDGRFQLFRIGDAVSSRSVHAAVLDAFRLCSAV
>NZ_CP040605.1|WP_168588087.1|5678240_5678414_-|DUF397-domain-containing-protein
MLTQQWIKSSYSSANGDCVELTTTLDAIRDSKDPHGPTLSVDVSTFVRAVQQGRFDR
>NZ_CP040605.1|WP_168588088.1|5678492_5678666_-|DUF397-domain-containing-protein
MNPKYWRKSSYSNVNGNCVELTTTLDAIRDSKDPHGPTLSVNVSTFVRAVQQGRFDR

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Crispr_ID: NZ_CP040605_22

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_22

5907275-5907440

Orphan

Consensus_repeat	Method
GAGGAGGGCGAGTACGGCGACGAAG	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP040605_22

>merge|NZ_CP040605|22|5907275-5907440|CRISPRCasFinder
TCCGAGGGCGAGTACGGCGAAGCCGAAGAGGGCAGTGAGGAGGGCGAGTACGGCGACGAAGGGGAGGAAGAAGCCGAGGAATACGGAGAGGAAGAGGAGGGCGAGTACGGCGACGAAGAGAACGAGAGGGGCGAAGAGTCGGAAGCCGAGGAGTACGAGGATGAAG

>NZ_CP040605|22|21|5907275-5907440|CRISPRCasFinder
TCCGAGGGCGAGTACGGCGAAGCCG	AAGAGGGCAGTGAGGAGGGC
GAGTACGGCGACGAAGGGGAGGAAG	AAGCCGAGGAATACGGAGAGGAA
GAGGAGGGCGAGTACGGCGACGAAG	AGAACGAGAGGGGCGAAGAGTCG
GAAGCCGAGGAGTACGAGGATGAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168590390.1\|5905658_5906351_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223044
NZ_CP040605.1\|WP_168588235.1\|5896206_5896344_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168588244.1\|5910934_5911258_+\|gas-vesicle-protein-K	unknown	unknown	gnl\|CDD\|377462
NZ_CP040605.1\|WP_168588236.1\|5897055_5901390_+\|cation-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|223550
NZ_CP040605.1\|WP_168588238.1\|5904758_5905187_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168588240.1\|5907539_5907962_+\|gas-vesicle-structural-protein-GvpA	unknown	unknown	gnl\|CDD\|236485
NZ_CP040605.1\|WP_168588245.1\|5911321_5911585_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|182475
NZ_CP040605.1\|WP_168588241.1\|5908767_5909019_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|310007
NZ_CP040605.1\|WP_168588242.1\|5909469_5909934_+\|gas-vesicle-protein	unknown	unknown	gnl\|CDD\|376379
NZ_CP040605.1\|WP_168590391.1\|5908036_5908765_+\|GvpL/GvpF-family-gas-vesicle-protein	unknown	unknown	gnl\|CDD\|377652
NZ_CP040605.1\|WP_168584374.1\|5912151_5912916_+\|transposase	unknown	unknown	gnl\|CDD\|372577
NZ_CP040605.1\|WP_168584131.1\|5895754_5896210_+\|MHS-family-MFS-transporter	unknown	unknown	gnl\|CDD\|340927
NZ_CP040605.1\|WP_168588237.1\|5904105_5904531_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168590393.1\|5910732_5910942_+\|gas-vesicle-protein	unknown	unknown	gnl\|CDD\|376379
NZ_CP040605.1\|WP_168588243.1\|5909926_5910709_+\|GvpL/GvpF-family-gas-vesicle-protein	unknown	unknown	gnl\|CDD\|377652
NZ_CP040605.1\|WP_168590392.1\|5909020_5909473_+\|gas-vesicle-protein	unknown	unknown	gnl\|CDD\|368618
NZ_CP040605.1\|WP_168588234.1\|5894140_5895295_-\|dihydrolipoyllysine-succinyltransferase	unknown	unknown	gnl\|CDD\|237001
NZ_CP040605.1\|WP_168588232.1\|5891622_5893077_-\|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl\|CDD\|319844
NZ_CP040605.1\|WP_168588233.1\|5893504_5893912_-\|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl\|CDD\|107221
NZ_CP040605.1\|WP_168588231.1\|5891162_5891429_+\|DUF3040-domain-containing-protein	unknown	unknown	gnl\|CDD\|378610

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168590390.1\|5905658_5906351_+\|hypothetical-protein	gnl\|CDD\|223044	PHA03325, PHA03325, nuclear-egress-membrane-like protein; Provisional.	0.00410063
NZ_CP040605.1\|WP_168588244.1\|5910934_5911258_+\|gas-vesicle-protein-K	gnl\|CDD\|377462	pfam05121, GvpK, Gas vesicle protein K. These proteins are involved in the formation of gas vesicles.	8.99924e-31
NZ_CP040605.1\|WP_168588241.1\|5908767_5909019_+\|hypothetical-protein	gnl\|CDD\|310007	pfam05120, GvpG, Gas vesicle protein G. These proteins are involved in the formation of gas vesicles.	1.86424e-14
NZ_CP040605.1\|WP_168588240.1\|5907539_5907962_+\|gas-vesicle-structural-protein-GvpA	gnl\|CDD\|236485	PRK09368, PRK09368, gas vesicle structural protein GvpA.	1.06828e-46
NZ_CP040605.1\|WP_168588245.1\|5911321_5911585_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|182475	PRK10457, PRK10457, hypothetical protein; Provisional.	3.88288e-17
NZ_CP040605.1\|WP_168588236.1\|5897055_5901390_+\|cation-translocating-P-type-ATPase	gnl\|CDD\|223550	COG0474, MgtA, Cation transport ATPase [Inorganic ion transport and metabolism].	0
NZ_CP040605.1\|WP_168588242.1\|5909469_5909934_+\|gas-vesicle-protein	gnl\|CDD\|376379	pfam00741, Gas_vesicle, Gas vesicle protein.	4.12759e-16
NZ_CP040605.1\|WP_168590391.1\|5908036_5908765_+\|GvpL/GvpF-family-gas-vesicle-protein	gnl\|CDD\|377652	pfam06386, GvpL_GvpF, Gas vesicle synthesis protein GvpL/GvpF. This family consists of several bacterial and archaeal gas vesicle synthesis protein (GvpL/GvpF) sequences. The exact function of this family is unknown.	8.03225e-60
NZ_CP040605.1\|WP_168584374.1\|5912151_5912916_+\|transposase	gnl\|CDD\|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.14619e-22
NZ_CP040605.1\|WP_168584131.1\|5895754_5896210_+\|MHS-family-MFS-transporter	gnl\|CDD\|340927	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli shikimate transporter (ShiA), inner membrane metabolite transport protein YhjE, and other putative metabolite transporters. ShiA is involved in the uptake of shikimate, an aromatic compound involved in siderophore biosynthesis. It has been suggested that YhjE may mediate the uptake of osmoprotectants. The ShiA-like subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.26523e-23
NZ_CP040605.1\|WP_168590393.1\|5910732_5910942_+\|gas-vesicle-protein	gnl\|CDD\|376379	pfam00741, Gas_vesicle, Gas vesicle protein.	1.77458e-08
NZ_CP040605.1\|WP_168588243.1\|5909926_5910709_+\|GvpL/GvpF-family-gas-vesicle-protein	gnl\|CDD\|377652	pfam06386, GvpL_GvpF, Gas vesicle synthesis protein GvpL/GvpF. This family consists of several bacterial and archaeal gas vesicle synthesis protein (GvpL/GvpF) sequences. The exact function of this family is unknown.	9.48466e-56
NZ_CP040605.1\|WP_168590392.1\|5909020_5909473_+\|gas-vesicle-protein	gnl\|CDD\|368618	pfam05800, GvpO, Gas vesicle synthesis protein GvpO. This family consists of archaeal GvpO proteins which are required for gas vesicle synthesis. The family also contains two related sequences from Streptomyces coelicolor.	1.59061e-28
NZ_CP040605.1\|WP_168588234.1\|5894140_5895295_-\|dihydrolipoyllysine-succinyltransferase	gnl\|CDD\|237001	PRK11856, PRK11856, branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed.	3.47018e-124
NZ_CP040605.1\|WP_168588232.1\|5891622_5893077_-\|HAD-IC-family-P-type-ATPase	gnl\|CDD\|319844	cd07544, P-type_ATPase_HM, P-type heavy metal-transporting ATPase; uncharacterized subfamily. Uncharacterized subfamily of the heavy metal-transporting ATPases (Type IB ATPases) which transport heavy metal ions (Cu(+), Cu(2+), Zn(2+), Cd(2+), Co(2+), etc.) across biological membranes. The characteristic N-terminal heavy metal associated (HMA) domain of this group is essential for the binding of metal ions. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	1.09086e-168
NZ_CP040605.1\|WP_168588233.1\|5893504_5893912_-\|Hsp20/alpha-crystallin-family-protein	gnl\|CDD\|107221	cd06464, ACD_sHsps-like, Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are generally active as large oligomers consisting of multiple subunits, and are believed to be ATP-independent chaperones that prevent aggregation and are important in refolding in combination with other Hsps.	1.6244e-26
NZ_CP040605.1\|WP_168588231.1\|5891162_5891429_+\|DUF3040-domain-containing-protein	gnl\|CDD\|378610	pfam11239, DUF3040, Protein of unknown function (DUF3040). Some members in this family of proteins with unknown function are annotated as membrane proteins however this cannot be confirmed.	3.0662e-11

>NZ_CP040605.1|WP_168590390.1|5905658_5906351_+|hypothetical-protein
MAVAVGYALGRSRKMKLAITAAGMLAGRRFADPKELLAKGGKLLGASPEVQKLTGQARERLLDAAKSAVLAAATSKIESLGDSLTERAAGLRTVNVEGAGEQLSGAGKEVTSLSKKAMRRRANSEEPPAADEDEIESGGDGEEQAAEQSSDGRTERHRTPEHSTPLSGRLARSATEAKETVRTSQSSAQGKSSSGASGRAGSRSGGSAGQGQRKQAATPRSKPSVPRKTS
>NZ_CP040605.1|WP_168588238.1|5904758_5905187_+|hypothetical-protein
MLVRIKVYLAAFVGYLLGRWRMGKAALRLARLLARKKLSSMPARRRAASNHRRLRLQRAGVTAASVMAGAGAAYAAYRMTRSVALESSEAEQPSGEGTPGEGAASLGESRDETIVPPEGAIPAAREAPKTKAKKAAKKGAQR
>NZ_CP040605.1|WP_168588237.1|5904105_5904531_+|hypothetical-protein
MASLDKAGARPRKFLARLAGWLREAAGRIVRDLLVKGSEVLHREVPAWLDKLANSASSSPSVQSGLAGLSAAIRGKHPLWPAVKAAVAGLSVKVKVLLVVGLALVLLLGPVLLVLLLLFLIVVAVIRTMRVRRTEELFTLW
>NZ_CP040605.1|WP_168588236.1|5897055_5901390_+|cation-translocating-P-type-ATPase
MLRTLGALASQIVAPVAAAARSIAGLESGRRAWASDGRAHVEVRGVHQPGSEDAGERVVRRLEKVPGVAWVEINAAVGRVVIGHDPDLVGIAGLVGAVEDAEAETGLDGEPFATVSADHPDNPVKVFAEVAMLGANLAGAAITMGAELLPLPALPPSVPALVSTGESASRVRGPLETRLGKTATDVLFGIGSAVANTLAQRRSSLLAESAYRFFLLRETQAAQRSWARWEAGVGRHPASHRSKPVAVVARPVPLPDGPVERAANGSALAGPAAFAGMLGVTRSFQRAQAMLVAGAPRAALVGRGAFAAQLGYGLSERTTLVFEPRVLRRLDRVDTVVIDAGVVRTGVRLVHDVIPAEGDHAAVELWERAHHLVGVTKADGTRREGWSLSSVARSRLPSDVRGAAGPGIEVFALRHDSRRVAWVLAAEELDPLAEELVAAARGVGSVVVAGDGGRLAARIGVDRVVAGGVRLASVVREMQREGSVVAVVSSQARAALAAADVGFGVTRDGVVPWGAHLIAGASLGEPCALLRNVSTARQVSRRSAQLSLIGSVGGAALAAFGPAIGSQARAGIPVAVCAAIALGAGTWWGMQAAWRPVPRAVPRTAWHAMAPGTVLELLDSSPEGLTDDSARQRFPDHDEGADFRRMGVLRASLEELASPLTPALAGGAAISASIGAVADATIILGVLGMNALIGGVQRITADRALNKLLAASVVRVVVRRKENVTQLPADQLVLGDVVELVAGDAVPADCRLLEADGLELDESSLTGESMLVTKTVTATPAVPVADRTCMIYRGTAVAAGRGVGVVVATGADTEAGSAIGPEVRRGADGVAARLQTLAKVTVPICLGAGGILLVTDILRGRRLGTSLGRAVSLAVAAVPEGLPFVATVAELAAARRLSKRGALVRNSATIEALGRAQVLCFDKTGTLTEGRIALRRVSDGASSRWLENISTVQRRVLAGALRASPLVDNGELLPHPTDRAVVDGARGAGVHPAEGKQGWVPIDEMPFEPSRGYHAVLGTFSDGNLLSVKGAPEIVLAQCTRWRRPDGDVPLEGTAGRDVERVAENLARQGYRVLAVAERAASDRSDLDESRIRDLRLIGFVALADPVRPTAAAAVAQLQQAGVEVVMVTGDHPSTAEAIAAELNALNERRVMTGTELDTLDDDQLAAEVATVAVFARVSPAQKARIVDALQRNDRVVAVTGDGANDAPAIRLADIGIALGQRATPAAREAADLVVTDDRIETIVDAIVEGRAMWASVRDSLAILLGGNLGEIGFTVVTGLINGGGSLNARQLLLVNLLTDILPAMAIAVRPPPTITAEMLLAEGPEASLGAALTHDIYRRAAVTAGAAICAWILGRATGSLRQANTVALVALVAAQLGQTLVVRGRTPLVVGCALVSFVALAAVVQTPGLSQFFGSSPLLPHGWMIAAGMATAATAISLLLQQW
>NZ_CP040605.1|WP_168588235.1|5896206_5896344_+|hypothetical-protein
MTLTVPSMAEVTDTPAQRPPDKLAASRYAVASGVDPERYLPHGTF
>NZ_CP040605.1|WP_168584131.1|5895754_5896210_+|MHS-family-MFS-transporter
MGALADRVGARRLSVYGLVGLAIGVAAFFPLLNTGQPTLAILVVALTNGIAGKAFWAPYAGIMSTLFSTEMRYSGMSFSFQLAGILGGGIAPFVAASLLELTDSWVPIMLYGLVAIAVSIGCVIAVRPHDRPASGIRAGVESASVGEEAKQ
>NZ_CP040605.1|WP_168588234.1|5894140_5895295_-|dihydrolipoyllysine-succinyltransferase
MTLGERRPMSTHVTMPALGENVTEAFITRWLKRAGDTVAADEPLLEVATDKVDTEVPAPFAGTIHELLAKENDTVAVGEPLAIVEPAGAGPASHSDAPPAPEPVTPPAVPTVTEPAPAPAVTATAPAVTATAPAVTATAPAVTATAPADDARVEKMSRLRQTIATRMVASLQGSAQLTTVLEADVTTLARLRARTKDAFEARTGTRLSFLPFFAKGAIEALREHPMLNASVSDDNTTATYHSACHLGIAVDTPRGLMVPVIRDADRLDVEGLAVAIADVAGRTRDGRISPDELAGGTFTITNTGSRGALFDTPILNPPQTGILGTGAIVERVVPRPDGTGGHTIAVRSMAYLSVSYDHRLVDGADAARFLSTIKNHIERADFSI
>NZ_CP040605.1|WP_168588233.1|5893504_5893912_-|Hsp20/alpha-crystallin-family-protein
MTSLQPRPSLGLPDIFQMFETEWPFGERHAMRVETYTEKDEFVVRCELPGVDPEKDIHINVEGNQLKITAERKHEERTDRHSEFYYGSFSRTLLLPTSCNTEDINAEYEAGILTIHMPRREAETRKEIPVMRKGK
>NZ_CP040605.1|WP_168588232.1|5891622_5893077_-|HAD-IC-family-P-type-ATPase
MSEPRSVPRWPNAARRVRLWFEPTLLAVTAGALLLGVIAWAVGATSTADAAWVAGTAVAIVPALTWMAHALWRGRTGVDLIAVLSLGGTLVVHEYLAGSLIAVMLASGQALDAAAQRRASHDLRALLEHAPRFAHRYADGALETVVVDQVSVGDLLLVNPGEVVPVDGQVGSTAAVLDESVLTGEPAHVERTAGEPVRSGVVNAGSAFDLRASATAEESTYTGIVRLAQDAGAERAPVVRLADRYATWFLPLALLLAGGAWLITGSPVGAVAVLVVATPCPLLLAVPVAIVSGMSRASRIGVIIRDGAALENLGHATTVIVDKTGTLTAGRPTVVDVIAAPTVDASEVLRMAASLDQASPHVLADAIVAHARKQHLALLPPRDATEQPGRGMSGIVDGKRVEVGRLALPENRPRWADAVLNRAMLDATAIAWVSCESELHGALLLRDPLRRDAPRTLRRLRNAGLHRPRGYRQRATCSGRQSPR
>NZ_CP040605.1|WP_168588231.1|5891162_5891429_+|DUF3040-domain-containing-protein
MLRRYERRLLEEIERQLCSEDPEFAQRMTHVRPFMKVLGWLTVRRALGIVTAFLALLCVVFNEGTGFFVAGALAAALFMSESWQIQTE
>NZ_CP040605.1|WP_168588240.1|5907539_5907962_+|gas-vesicle-structural-protein-GvpA
MTVASMQGGGGSPVQRGSSGDLAEVVELILDKGLVIDVFVRVSLVGIEIATVDARVVVASVDTYLRFAEVTNRLDLEQKGGKDLPELMEGMTQSGVEGKTKGVIDAAKDKFDEFRGSEQAERREKQPVKRREPRSRERER
>NZ_CP040605.1|WP_168590391.1|5908036_5908765_+|GvpL/GvpF-family-gas-vesicle-protein
MYVYGIIGRREELPDELPSVGGDEAKVVLASRGELSALISEVRLVRPLGTREDLLAHERVLDTLAAETTVIPMRFGSVVTTEKAVVEELLDPHHDHFEAMLTELEGLVQFTVRGRYAESAHLREIVADVPEVRQLREDLSGLPEDAGYAERLRLGELVSNAVAQKRESDAETLIASLEPSSAASLSHAVAAEDDAVHVTFLVDREEIPQFEQAVDELGERWAGRIDLRLIGPLAPYDFLPGA
>NZ_CP040605.1|WP_168588241.1|5908767_5909019_+|hypothetical-protein
MGLITGLLTLPLAPVRGVVWVAEQVKQHAEQQYYDPALIQRQIADVDDAYAAGALSDSERDRLHEDLLNRLFEAQRRRRGEEM
>NZ_CP040605.1|WP_168590392.1|5909020_5909473_+|gas-vesicle-protein
MVATVRREGSGDREPPAERRRRNPPRQPASRTPTTKSSPEQGRNPERARQKHDSDDDKGRAQEQHSLKAAQVARLAVRQVHELTGRQPEGVTSLERSETGWVVGVEVVESRRVPDTADVLAVYEAELDDDGDLVSYRRVDRYARGRGNER
>NZ_CP040605.1|WP_168588242.1|5909469_5909934_+|gas-vesicle-protein
MNGYDGSDRATAPAVRGGGARAPTWYGERATSAQPQSANLADILERVLDKGIVIAGDIQVNLLDIELLTIKLRLVVASVERAREMGIDWWEHDPTLSSGHRDLVEENRSLRSQVRELESGRSTTEAALEEGADEPFPEPHREVRERSTEEQDRG
>NZ_CP040605.1|WP_168588243.1|5909926_5910709_+|GvpL/GvpF-family-gas-vesicle-protein
MAETLSYVYAILRAGVDISVRVAGIAGSEVRLVTSGGLAALVSTVDAGEFGEQGLRKNLEDMGWLETTVRAHSRVVEAAISAAPVAPLALATVYYSDDRVRAALAERGPAFADILELISGHAEWGVKAFADVSKREQREPTASGPGGSQERPGQAYLGKLRERRKGQAEAERDALQQAEEVHAALSDLSHANRVHPPQNRDLAGYQGLMVLNGAYLVDDARTEEFIAAVESIAAESALRIELTGPWAPYSFAMVEGADQR
>NZ_CP040605.1|WP_168590393.1|5910732_5910942_+|gas-vesicle-protein
MSPLTVRDSREIALVDLLDRLLAGGVVLAGDVTISLAGVDLVRVSLRAIITSIHEVTVDADSWEQVDDG
>NZ_CP040605.1|WP_168588244.1|5910934_5911258_+|gas-vesicle-protein-K
MGESSRDHRPERQRGLPHRIETDAESVQRDLVRLVLTIVELLRQLMERQALRRVDAGGLDEDQVEELGLALMKLEEAMAELRDRFGFAVEDLNLDLGPLGPLLPRDD
>NZ_CP040605.1|WP_168588245.1|5911321_5911585_-|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MGILSWILFGLIAGAIAKFILPGRDPGGIIVTILIGIVGGLLGGWISTRVMGGAGVSGFNVMSFVWAIIGSLILLLIYRLIIHRTHA
>NZ_CP040605.1|WP_168584374.1|5912151_5912916_+|transposase
MRYQSTTGLAADQIEELVVRIWQIVQCRGKQPWPLTVGLYRAVVITLVYVRQNLNQAAVGDLFGLSQPTVSRIYRGILPLIGEALCLHIPDLKDAIRGRLVLVDGTDVPTGNRAGHEVNYSGKRRRAGLNIQIAADTDGDLLGISAPMRGSMHDRKAFDECGWEDRLSDTPTIADPAYQGTHAITPRKKPKGGELSTNDKSNNKTISSIRSAVERCIAHVKNWKILATGYRGRLAELPTIIRIIAALEFYRLGW

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Crispr_ID: NZ_CP040605_23

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_23

7947931-7948021

Orphan

Consensus_repeat	Method
CGACCAGTGCCCGTCCGGTCGTGAGTGGCAAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040605_23

>merge|NZ_CP040605|23|7947931-7948021|CRISPRCasFinder
CGACCAGTGCCCGTCCGGTCGTGAGTGGCAATGCCGGTTCTTACCGGAACCACCACTCACGACCAGTGCCCGTCCGGTCGTGAGTGACAAT

>NZ_CP040605|23|22|7947931-7948021|CRISPRCasFinder
CGACCAGTGCCCGTCCGGTCGTGAGTGGCAAT	GCCGGTTCTTACCGGAACCACCACTCA
CGACCAGTGCCCGTCCGGTCGTGAGTGACAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168589647.1\|7948117_7948525_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168589652.1\|7955394_7955535_+\|SapB/AmfS-family-lantipeptide	unknown	unknown	gnl\|CDD\|380211
NZ_CP040605.1\|WP_168590635.1\|7939882_7940848_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|179559
NZ_CP040605.1\|WP_168589655.1\|7959756_7961217_-\|beta-glucosidase	unknown	unknown	gnl\|CDD\|274539
NZ_CP040605.1\|WP_168589649.1\|7949833_7950799_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168589648.1\|7949251_7949590_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168589645.1\|7945781_7946783_-\|SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|366359
NZ_CP040605.1\|WP_168589642.1\|7935301_7936489_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168589643.1\|7942867_7944529_+\|prenyltransferase	unknown	unknown	gnl\|CDD\|239219
NZ_CP040605.1\|WP_168584127.1\|7937264_7937447_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168589644.1\|7944525_7945773_+\|FAD-dependent-monooxygenase	unknown	unknown	gnl\|CDD\|223727
NZ_CP040605.1\|WP_168590636.1\|7941914_7942871_+\|UbiA-family-prenyltransferase	unknown	unknown	gnl\|CDD\|260119
NZ_CP040605.1\|WP_168590637.1\|7961224_7962046_-\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_CP040605.1\|WP_168589653.1\|7955627_7957286_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP040605.1\|WP_168589650.1\|7951328_7951793_+\|Lsr2-family-protein	unknown	unknown	gnl\|CDD\|378714
NZ_CP040605.1\|WP_168584149.1\|7939471_7939954_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168589654.1\|7957282_7959028_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP040605.1\|WP_168587112.1\|7937770_7939039_+\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|379017
NZ_CP040605.1\|WP_168589646.1\|7946948_7947788_+\|taurine-dioxygenase	unknown	unknown	gnl\|CDD\|181947
NZ_CP040605.1\|WP_168589651.1\|7952792_7955327_+\|protein-kinase/lanthionine-synthetase-C-family-protein	unknown	unknown	gnl\|CDD\|271199

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168589643.1\|7942867_7944529_+\|prenyltransferase	gnl\|CDD\|239219	cd02889, SQCY, Squalene cyclase (SQCY) domain; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY) and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization cascade converting linear triterpenes to fused ring compounds. Bacterial SQCY catalyzes the convertion of squalene to hopene or diplopterol. Eukaryotic OSQCY transforms the 2,3-epoxide of squalene to compounds such as, lanosterol (a metabolic precursor of cholesterol and steroid hormones) in mammals and fungi or, cycloartenol in plants. Deletion of a single glycine residue of Alicyclobacillus acidocaldarius SQCY alters its substrate specificity into that of eukaryotic OSQCY. Both enzymes have a second minor domain, which forms an alpha-alpha barrel that is inserted into the major domain. This group also contains SQCY-like archael sequences and some bacterial SQCY's which lack this minor domain.	2.71828e-26
NZ_CP040605.1\|WP_168589655.1\|7959756_7961217_-\|beta-glucosidase	gnl\|CDD\|274539	TIGR03356, BGL, beta-galactosidase.	0
NZ_CP040605.1\|WP_168590637.1\|7961224_7962046_-\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	3.56471e-69
NZ_CP040605.1\|WP_168589645.1\|7945781_7946783_-\|SAM-dependent-methyltransferase	gnl\|CDD\|366359	pfam00891, Methyltransf_2, O-methyltransferase. This family includes a range of O-methyltransferases. These enzymes utilize S-adenosyl methionine.	3.22415e-36
NZ_CP040605.1\|WP_168590635.1\|7939882_7940848_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|179559	PRK03321, PRK03321, putative aminotransferase; Provisional.	2.37852e-115
NZ_CP040605.1\|WP_168589650.1\|7951328_7951793_+\|Lsr2-family-protein	gnl\|CDD\|378714	pfam11774, Lsr2, Lsr2. Lsr2 is a small, basic DNA-bridging protein present in Mycobacterium and related actinomycetes. It is a functional homolog of the H-NS-like proteins. H-NS proteins play a role in nucleoid organisation and also function as a pleiotropic regulator of gene expression.	9.3334e-26
NZ_CP040605.1\|WP_168589644.1\|7944525_7945773_+\|FAD-dependent-monooxygenase	gnl\|CDD\|223727	COG0654, UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion].	6.48784e-43
NZ_CP040605.1\|WP_168590636.1\|7941914_7942871_+\|UbiA-family-prenyltransferase	gnl\|CDD\|260119	cd13956, PT_UbiA, UbiA family of prenyltransferases (PTases). Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.	2.41966e-37
NZ_CP040605.1\|WP_168589653.1\|7955627_7957286_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.31977e-79
NZ_CP040605.1\|WP_168589652.1\|7955394_7955535_+\|SapB/AmfS-family-lantipeptide	gnl\|CDD\|380211	NF033212, SapB_AmfS_lanti, SapB/AmfS family lantipeptide. Members of this family are class III lantipeptide precursors. These typically are short peptides, encoded next to the gene for the lantipeptide synthetase that creates the characteristic lanthionine (or beta-methyl lanthionine) bridges for which these natural products are named. Members of this family include SapB and AmfS, which are considered morphogens rather than antibiotics. Members also include labionin-containing peptides such labyrinthopeptins A1 and A2.	0.000191918
NZ_CP040605.1\|WP_168589654.1\|7957282_7959028_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	9.7955e-68
NZ_CP040605.1\|WP_168587112.1\|7937770_7939039_+\|IS4-family-transposase	gnl\|CDD\|379017	pfam13006, Nterm_IS4, Insertion element 4 transposase N-terminal. This family represents the N-terminal region of proteins carrying the transposase enzyme, DDE_Tnp_1 (that was Transposase_11), pfam01609, at the C-terminus. The full-length members are Insertion Element 4, IS4. Within the collection of E.coli strains, ECOR, the number of IS4 elements varies from zero to 14, with an average of 5 copies/strain.	3.0491e-31
NZ_CP040605.1\|WP_168589646.1\|7946948_7947788_+\|taurine-dioxygenase	gnl\|CDD\|181947	PRK09553, tauD, taurine dioxygenase; Reviewed.	5.71883e-88
NZ_CP040605.1\|WP_168589651.1\|7952792_7955327_+\|protein-kinase/lanthionine-synthetase-C-family-protein	gnl\|CDD\|271199	cd04791, LanC_SerThrkinase, Lanthionine synthetase C-like domain associated with serine/threonine kinases. Some members of this subgroup lack the zinc binding site and the active site residues, and therefore are most likely inactive. The function of this domain is unknown.	1.05775e-101

>NZ_CP040605.1|WP_168589646.1|7946948_7947788_+|taurine-dioxygenase
MTENRFDVRPVSGALGAEVRGVPLDALTDSDFTALRELLLNHLVLFFPDAAGLEPEAHKAFGRRFGELEVHPFLPKLPGHDELVVLDSDQGARADVWHTDVTFSPSPPIASVLQLVECPPAGGDTMWSNQYLAFEALSAPVRDLLEGLTAVHVFEHPNGSFRSEAEHPVVRTHPETGRRSLYVNRMFTRRIPQLTSGESDALLNHLFEVSESPQRVCRYRWIPGAVAVWDNRATQHYAVNDYTGRRVGRRVTVLGDKPVGEPARWPHHEEGVLSASTSK
>NZ_CP040605.1|WP_168589645.1|7945781_7946783_-|SAM-dependent-methyltransferase
MPHDAAAELARLVDLATPFAIRTAVALRLPELVEAGTTGLAELAAASECDEDSLARLLRHLVSVGLFAETAPGAYGLTPLSRELLGEDHRWQRGWLDIGGPGTKMDLAYTGMLHSVRTGESAYGRVHDVEFWADYQRDERLRLFFGAIMAAHAWQTGPAVAAEYDWSGVRRVLDVGGGTGALLSEVLLKHQHLTGAVLDLPPVRPEAEQAFAEAGLSERAEFVGGSFFDPLPAGYDVLLVSRVLTDWNDENATKILRRCGEAAGPDGRVAIVEVLAGEEHAKNNSSFDLQSLTLLGGRERSVNDFHALAAAAGLSVHATHRWPSGLVVVECTG
>NZ_CP040605.1|WP_168589644.1|7944525_7945773_+|FAD-dependent-monooxygenase
MSYDVVVCGAGVAGLAAACALGRLGRRVLLVDKQERVRPVAKGEVFQPGALAILHEWGVALRLEAAGALRLGKLVARDAEGRAQMALDYARLPVQRNWLLAHDYPAILEALAKSLPDNVEFCRGELVTGLIFTGGRVTGVRIGDDVVEAALVVAADGVSSRLRREAGIEIRRDDYPHRLVALELHDAPEVEPDFSAYVTPRGLRLRYPLPAGRIRLYAQTGAHEMRGLNAGGLDRWATDLVRETPALAPLEASIRTHLAARQLLPVPRFLAPSLAVPGLALVGESGHTVHPMAAQGMNSAIADAHELATMLRQGGSLAPAAVDHALARYSAARRENLAHIGRTSHNAARMITDLSWVGRFAGRRALRGTGGNDRIRYTVMHTMSGLGVHPLTPLDRLHQLGLLPDPRARRLPSWA
>NZ_CP040605.1|WP_168589643.1|7942867_7944529_+|prenyltransferase
MTFPRSDQITEAITEGAEALFAAQREDGVFDYGGASLTSTLGTVGAVCALHFADPGGAADLIEAGVGWLKRTQAADGGWAMVPGEASEAGPTAVASAVLHLTDPRGNAAAVGAGQEWMREFGGLEAIPHAEVVAWCRQFYGFAGWLDAREMRRFPLELALLPGLYRRLFDLRAPMVSALGLAQARHKPLTRLQRSLAKLAEPNALAVIRQVYEHEGSTGGWCEDAWVTGLICAGLARAGLGGDMVDGAVGWFRRMAAPDGSWSSGPLDLTWSMYATAGLLEAGYAADPRLAAVKELFLRLQQDQPFTAFGCAPGFWGWSGTRGWPATLETGEILSALNHLPGTDQADAVRRGVTWLTLQQDTRGSWGLCVRNTKVANSGPCPHMTAQAVDGLLDSGVPAEDRRVRRALRWLGKAQKPDGSFESVWYRMHTAGTSAVLQTFVKAGAAEGEPARRARAWLERTRLADGSWGTGDGEPGTVEETGWAVSALLAAGAEPDSARSGVDWLLAHRLPAGGWPAANVNEYVRHVCRYPNPALAHGLALKALARYRKAVAG
>NZ_CP040605.1|WP_168590636.1|7941914_7942871_+|UbiA-family-prenyltransferase
MQTWRPYTSCYPALLGLAGTAVAGGAGRADALVVAALAPTLGWLSGHYLGDYFDRNLDAIGKPHRPIPSGRLSTEAALCGGLACAALSAVLVVWANWRIVPLFVVAVAGIVGYSKVFKSRGIAGNVTRGALTALALVIGAMVAAPWPPWPLLPVAAGFLLHDTASNLVGTVRDVDGDRAGGYRSVPVRRGVRHAVRHALRLYSGGVALVVFGAVWATTDPAAQLAITAVAAVIGARAFTPLVRAGDVVGARTALRAHELLVAERLALAAAVIAGATGSRFALALVLPVLLFSLLTQALMRARHEFPPAPTVAGRKDPA
>NZ_CP040605.1|WP_168590635.1|7939882_7940848_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MNENTSRPLPGVLEAAESSLGRMHLTLDALATGLTNAIAERFAIAPERVVAGAGSGALLQQFLTAHSGAGTSVVHAWPSFELYPLLIRNALAEPVAVPSDGDCQDLAALAAAVTPQTKIVLLCNPNNPTGEVLGRAELADFLAALPPHVLVLIDEAYREFADPAHIADGLALAAADDRVAVVRTFSKSHGLLGLRVGYLVAAEPVAAALRPMLPFYRVPTVAQAAALAALDAEDAMRERCRVVAAERDRVRTGLLDLGWDVPPSGGNFLWLRLGDRNKSFVDHLAARGVVVREIAGAGVRVSTGTPEANDALLVLAKEFAR
>NZ_CP040605.1|WP_168584149.1|7939471_7939954_-|hypothetical-protein
MHAAEAAFGRFEHAGQWSGSVFVQGQLMNDLSHVNEGLSVAAHGISNACHHILDQSLRQIAGSRDHCQAAESIVHQTKIGNRVCFPGTVTGISGTIQDGESTVGRQFRSIACAMSTLRFPGRDESVSVGGSAKAARSSVSTSKPGASRTCRARSAAHPKH
>NZ_CP040605.1|WP_168587112.1|7937770_7939039_+|IS4-family-transposase
MISGVVDDGVVAGARLTDLVSLGVLASSVPRDVVDEVIVAAGRQAKRSDGKLPPHVMVYFVMAMALFATEDYEEVAARLTDTLAAWGCWDQQWSLPTSGGITQARQRLGAEPLAELFARVAVPVAGELTRGAFLGPWRLMAIDGFEWDAPDTKANGAEFGYGGSGESRSAFPKVRVVSVSECGSHAMVDAEIGGVTGKGSGEQTLARRLYGRLQPGWLLIADRNFYTWQDWCTAADTGAELLWRVKSNTRLPVLGSLYDGSYRSVLIEAKIRGRARQALIDAAARGEDLPPDQARIVRVVEYTVPDRDGNGKGELIRLITTITDPTAAPAAALAESYHHRWEHETANGQIKTVLRGPGRVLRSKSPDMVRQELYGYLLTHYAISALICRAATEADIDPDRVKFTRTVRIVRRRIADPAAFSP
>NZ_CP040605.1|WP_168584127.1|7937264_7937447_-|hypothetical-protein
MTALLLMLRRSVAKAEDEVRGELLTDLLTSPDRNRGALLACRGRRRPASPPNCDPSWTSR
>NZ_CP040605.1|WP_168589642.1|7935301_7936489_-|hypothetical-protein
MLRLEPSPQTAGVPVPWCATAVGKVQLTERFTLHSSAPECKSLRRARRGLEHLLSVLGARDVALGGAAVEESSPAGGSWFVALGEENDRHWVRAAGLSQLRARQVAVDEVVLSSGLCLWGTGALCAVGAAGAVELTRAPQPEQVRTLHTLRADAELSAYETTTSAALAGLAGALARWAAIRVPSTMDWDIPRLHYLAALLDEQGAPMLAPELWQYWQDLVRQRNAQVHALVERRCLVEGLHAVGVEGLAGIADIARGRLPGTTPRQALRFLADADPVWRRIAATEQVTSYSELVRLAYVVQVLRAGCPELHGRSGRLLICVEDPAESRILSAARTVAERAGLDLQAVGLHPLGTLLPSTGGSLHACGLPKPRRETDRHKGDAGANPFRWTRKVPL
>NZ_CP040605.1|WP_168589647.1|7948117_7948525_-|hypothetical-protein
MGVKNAVKRVVVGLGATGLLSGALLTGTVATASASTIPKGHIQICAQGNYSAYVEVHPAELGGGMTTVGMSSTVQRPGNCWIHRLSTHGVDAPVDVWGIRPDGSTFHVGAASYNSKDGLGLGAQGTVSRPTMAKW
>NZ_CP040605.1|WP_168589648.1|7949251_7949590_-|hypothetical-protein
MRSTANWRATAAVFLMAFSAITALGPAAAANPVADSGIAPMETTAPKCMLDKEKKGKIYTTVWVTNSCKRNYRVQLIMARGADSRCFSITPGQTRSHTSRGISPYLDRIILC
>NZ_CP040605.1|WP_168589649.1|7949833_7950799_+|helix-turn-helix-domain-containing-protein
MEILGVKPRDAVEFVALMRRLKQESQLTYRQLEERAAARGEILARSTLADVLGGKRLPRPELLTAFVHACGRGSEATAWLDALDVIARGEALEHGLDKADPAPTEPAEAAPTEPVRHGQPSDKRFKGHLLPLTMAAAFGAVTASVAWMLIPFGRPAGDVQHTESTTSGIWSTLPRGWVRLRPVTALHLCLTDGRVQNYRYVPLVAVQRPCDEVAPQTTLLEPTGEGNYRIQWHHPDYGRGCLKALSEGPGAGLLEPRDDCEQGSSFEIEPSGLYGSGQYVLRVKGQGCVGIVGSSTAEGTEAEMEPCVGKGGQVFVIDLLP
>NZ_CP040605.1|WP_168589650.1|7951328_7951793_+|Lsr2-family-protein
MAERIQVELVDDIDGSLANHTVTFALDGVTYEIDLNDEHAQRLRAVLDRYIKAARAPKPEPARSTRQQEREEEQVRQANKQLTEQIRGAAQRTREHLSKKAAEPVKPQPVKPETVKQPEPVEETLFNTTPAEEPKPGAARVPAVSMPQFSSAVD
>NZ_CP040605.1|WP_168589651.1|7952792_7955327_+|protein-kinase/lanthionine-synthetase-C-family-protein
MDLRYEAFCFADPLFFDEQHRPSGLHDDYATLLSAPAEDWIESNLGTWRMLRPHDVDLPDQGWKVHVSATLDNAERVLSTVHEYCLRERVAFKHLRSPKVLLSRNAKYAPRSASGKFVTIYPLDEHQLELVLEELSQQLRGEAGPYILSDLRYGPGPLYVRYGGFVERSVELDGTRVLAIQGPDGALVPDKRGTSFSVPDWVNVPDCLSASLDARKSGDRAALPYRVTSSLHFSNGGGVYRAVRDADGEQVVLKEARPHAGLDRDGTDAVARLHRENDILRRLADIDGIPTAHELFQVWEHTFLAMDLVPGVPLGSWLARRYPLTRQHPDEHEIADYTDRAVDLLEKVERLLDRVHERGVVFGDLHALNVLVDEDGGVSFIDFEMASADDDAPRPALGAPGFRAPKGRTGFAIDRYALAALKLWMFLPLNPLLELSPGKLSGFVEVIERRFPLPNGYGDSIRNELAPADVVSATELDQPNPDWGVVRKGLAEAILCSATPERDDRLFPGDIEQFRLGGTGFAYGAAGVLHALDVAGTGRYPEHERWLVDAVRRTPPARPGFFDGAHGIAYVLENLGHHDEADALLAGAELLVTQTRDHGFAAGLSGIALNLLHFAGSREDREFREHAHNLGDHLADALTRALPPGEVGRAGLLDGWSGPALLFTHLYNDTGDRGWLELADRALSRDLDECVTTDDGVLQVRDGHARTLPYLAVGSAGIALVAEELAARHPDASCLRRQSDLLRGCVGEFVIHPGLLFGRCGLLAALAAAHRRSPDPILAEAIARHLSALGWHAIPYGDGGIAIPGNQLLRLSMDLGTGGAGVLTTVAATLDGHGRVLPFFGALT
>NZ_CP040605.1|WP_168589652.1|7955394_7955535_+|SapB/AmfS-family-lantipeptide
MGTILELQELDAQNDLGYGDSNYGGASNLSLLAACAQSTVSLLTCQ
>NZ_CP040605.1|WP_168589653.1|7955627_7957286_+|ABC-transporter-ATP-binding-protein
MAGVGDRVLRSVVEQDRGAAALLVLTALLTATAGLLLPSALAGAVDAVITGDGGPARVMWLVSLGSVQIIGEVMGVALTARLTASATARLRVRLVAGLIRGGNRSVLANGDAVSRISSDCTGAGQITANVVQLGTALVLSAGAVTALALLDWRIAVVFLCATPLAALLARSHLRHTATDLLAYQENSSELGARLLDAVGGLRTIAAAGVADQETARVLRPLPRLSAAGAGVWRTQARMMWRAGLLLPCVQVAVLGTAGVGVLTGDISVGDVLAALGYTTLGLGLVRQIPLFTALARARSCATRIAEVVDGDPEPAPHRLLPRGPGRLELRGVGVDGALSDVDLVVPGGDTVAVVGRSGSGKSVLAELLGGLRRPDRGHVLLDGLATHVVARSAIGYGFERPTLLGDTVGAAVAYGTGADADDVRSACRLADVHGLINRLPARYRTPLAQAPLSGGEAQRIGLARALVRRPRLLVLDDATASLDTVTEARVEAAISTALPDLTRIVVTHRAGTARRADAVLWLEDGRVRAIAPHDVLWIDPAYRAVFTEEGQP
>NZ_CP040605.1|WP_168589654.1|7957282_7959028_+|ABC-transporter-ATP-binding-protein
MTVTAGYWRALSGHWRDWSVLLACSALEALPAFLSGGLVQRAVDEGFAAGRVAVGFAWLAAFAAAAVAGAVGVRLVWQRLGTIVEPLRDTLVRTVVQGVLHETAPPRGGPDAAGVARITQHVEIVRDATAGLLVQARGLVVMVVGALAGVATMSGPLIWLIGPPIVGAVGVFLCLLPALARRQRGVAMADEHTATTAGAVLAGTRDVVACGAQNIADATVRAAITAQANASVLMSNAAALRTAVVAVGSFLPIVLVLAAAPGMNTDGRLSAGAVVGVLVYLTGTLQPALHGFAATMSTVVLRLLVTLNRLGEAQPPVRRTGGAEPGDGTITVRGLTHRWGGHAEPVLRDFELQLRPGDHLAVVGPSGIGKSTLAGLLTGTITPCQGEVLLGGVPINAVDPAHRARIIAFTPQETYLFAGSVRENLALLAPDADDTHLLTAVNAVGAAGLVERLGGLSGALAHGGVGLSSGERQVLALARVYASPARIIVLDEATTHLDGAAEARAERAFAERGGILVIIAHRLASARRARQVLVMDGRQALLGEHDDLLVRSSHYGELMQAWTGMPKTAAAKSYPAPGKLR
>NZ_CP040605.1|WP_168589655.1|7959756_7961217_-|beta-glucosidase
MTNGQELAFPPGFAWGVATASYQIEGGAKEDGRGASIWDTFTAREGTVVNGDTGETACDHFHRYPEDVALIAELGFPTYRFSVSWPRVMPDGRTLQPSGIAFYDRLVDELLSHGINPMVTLYHWDLPQALEDTGGWRVRDTAARFADYAATVYSALGDRVQEWTTLNEPFCSAFLGYGNGVHAPGIVDPGTALVAGHHLLLAHGWAMDVLRTAASPGQRFSIVLNFSPVLVDVDDEPHREAARKFDGMHNRLFLDPVLGRGYPEDVLGDVAHLQALEPAIHEGDLTTIAAPIDWLGVNYYAPTRVAPLPDPTEPSNCGLPGLRGFNVLPPRGPLTSFGWEQTPESLTDLLLWLHRHCPDLPLVVAENGAAFPDAVDFDGRIRDGERIRYFAEHLRAVHRAIEQGADVRGYLAWSLLDNFEWAMGYSQRFGLVHVDFDTQQRTIKDSARFYSHVVAANAIPDGVSNAILDGASNAIPDGASVDRVAD
>NZ_CP040605.1|WP_168590637.1|7961224_7962046_-|carbohydrate-ABC-transporter-permease
MDRRPGVLVYGFLFAVVATSVFPLYWSFVVASSDGSAIGEVTPPLIPGGYFLDNVRRVFDTVDFWLAIQNSLIVSGTVMVSTVVLSSFAGFAFARLRFPGRNTLFLVVLGTVMVPAQLGVVPLYMVVGNFGWYGRLEAVIVPGLINAFSVFWMRQACEEAVHVELVDAARVDGCSLWGTFWHVAVPAIRPQAAVLGMVTFMAAWNDFFWPLIVLDPNESPTVQVALSRLASGYFLDYSLMLTGTTLGVLPVIIVFVLLARQIVNGITRASVNG

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Crispr_ID: NZ_CP040605_24

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040605_24

8037671-8037751

Orphan

Consensus_repeat	Method
CAACACCCGGTACCCCACCGAAAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040605_24

>merge|NZ_CP040605|24|8037671-8037751|CRISPRCasFinder
CAACACCCGGTACCCCACCGAAATGTGCGGGTAGCGGTGTGCCCGGCCGGTCCGGGTCAACACCCGGTACCCCACCGGAAT

>NZ_CP040605|24|23|8037671-8037751|CRISPRCasFinder
CAACACCCGGTACCCCACCGAAAT	GTGCGGGTAGCGGTGTGCCCGGCCGGTCCGGGT
CAACACCCGGTACCCCACCGGAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040605.1\|WP_168589684.1\|8005268_8008691_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|163057
NZ_CP040605.1\|WP_168589690.1\|8033614_8033992_-\|DUF397-domain-containing-protein	unknown	unknown	gnl\|CDD\|377231
NZ_CP040605.1\|WP_168589693.1\|8041258_8042047_-\|IS630-family-transposase	unknown	unknown	gnl\|CDD\|315923
NZ_CP040605.1\|WP_168589695.1\|8045101_8045842_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274008
NZ_CP040605.1\|WP_168590641.1\|8016751_8017288_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238430
NZ_CP040605.1\|WP_168589691.1\|8034013_8034217_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168589686.1\|8009679_8013234_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223021
NZ_CP040605.1\|WP_168589685.1\|8008675_8009683_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168589689.1\|8028408_8031738_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236090
NZ_CP040605.1\|WP_168589688.1\|8015404_8016679_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379730
NZ_CP040605.1\|WP_168584151.1\|8026989_8027358_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168589687.1\|8014107_8014677_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168590642.1\|8042046_8043861_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040605.1\|WP_168589694.1\|8044271_8045108_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369417

Protein	Function_ID	Function_description	E-value
NZ_CP040605.1\|WP_168589686.1\|8009679_8013234_-\|hypothetical-protein	gnl\|CDD\|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	7.57828e-17
NZ_CP040605.1\|WP_168589690.1\|8033614_8033992_-\|DUF397-domain-containing-protein	gnl\|CDD\|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	9.25888e-06
NZ_CP040605.1\|WP_168589689.1\|8028408_8031738_-\|hypothetical-protein	gnl\|CDD\|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0.00108415
NZ_CP040605.1\|WP_168589688.1\|8015404_8016679_-\|hypothetical-protein	gnl\|CDD\|379730	pfam15567, Imm35, Immunity protein 35. A predicted immunity protein with an alpha+beta fold and a conserved tryptophan residue. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, usually containing a protease domain such as Tox-PL1 and Ntox40. In some instances, it is also fused to a papain-like toxin, ADP-ribosyl glycohydrolase and a S8-like peptidase. Based on these associations the domain is likely to be a protease inhibitor.	3.75762e-19
NZ_CP040605.1\|WP_168589693.1\|8041258_8042047_-\|IS630-family-transposase	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.73093e-33
NZ_CP040605.1\|WP_168589684.1\|8005268_8008691_-\|AAA-family-ATPase	gnl\|CDD\|163057	TIGR02881, Stage_V_sporulation_protein_K, stage V sporulation protein K. Members of this protein family are the stage V sporulation protein K (SpoVK), a close homolog of the Rubisco expression protein CbbX (TIGR02880) and a members of the ATPase family associated with various cellular activities (pfam00004). Members are strictly limited to bacterial endospore-forming species, but are not universal in this group and are missing from the Clostridium group. [Cellular processes, Sporulation and germination].	3.7565e-81
NZ_CP040605.1\|WP_168589695.1\|8045101_8045842_-\|hypothetical-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	2.78969e-05
NZ_CP040605.1\|WP_168589694.1\|8044271_8045108_-\|hypothetical-protein	gnl\|CDD\|369417	pfam07544, Med9, RNA polymerase II transcription mediator complex subunit 9. This family of Med9 proteins is conserved in yeasts. It forms part of the middle region of Mediator. Med9 has two functional domains. The species-specific amino-terminal half (aa 1-63) plays a regulatory role in transcriptional regulation, whereas this well-conserved carboxy-terminal half (aa 64-149) has a more fundamental function involved in direct binding to the amino-terminal portions of Med4 and Med7 and the assembly of Med9 into the Middle module. Also, some unidentified factor(s) in med9 extracts may impact the binding of TFIID to the promoter.	0.000788492
NZ_CP040605.1\|WP_168590641.1\|8016751_8017288_-\|hypothetical-protein	gnl\|CDD\|238430	cd00834, KAS_I_II, Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.	4.00154e-45

>NZ_CP040605.1|WP_168589691.1|8034013_8034217_-|hypothetical-protein
MLLRVPSPGQAGPLELAYVEGVAEIRYIDDKKALAAHVTAWARLSAAALNFAETRKFLAQVAREFKE
>NZ_CP040605.1|WP_168589690.1|8033614_8033992_-|DUF397-domain-containing-protein
MNTTPPLFAEGEFRKAARSQPDLSCVCVARRDGWVELRDDKTVFGGPDDHWLVFTAEEFDAFLAGAREGCAEGLCLEVTRRDADGMYVFRRRGWAAVELVFTDAELLAFQDGVINHEFDAIAYTA
>NZ_CP040605.1|WP_168589689.1|8028408_8031738_-|hypothetical-protein
MRTGFSGKAADRFADGLGIFDGLLSSGQGSLLDLAVFVRKTSQQVRYLKLMTIYSLELLWLEMAWAMRFAGATGGATLLWLAARMAAMRVWLTTWWGQLFMRLAMMAAGGVAFNVVPDVQAQAQMLGEKSARKWDGTLTEQAAGMGAFSALVALPLSAVGGLVSNTLTKVLVKGLGDDVDAAILEAAAKKAVAEHAELYPVSAMAKFADVVAEHLDDYAGMSVRAMWLARFGSGLGDALAGSLSELFGEVAYAAAAGLPLTWNPYSLTAGGFETVFSGLGTLAGLALRGKLHPQGPSPYLEGTGRGGDGSDDGGGSGEEKTPPPGIGSGSQTGNIPGSPDKDDSTFVPSDASRSDGSRSDRWTGSDFSNVSDVDSVFSDTGSVDSAAVPVPSGKDLVVSAVVDGKDSKDVQDGTHVKGGKEGAGGGGKGGADDGTPGETPARGVPAVPGSGQHQPGTPPPAYSGEVTGFGPDRPGTPPPPYSPGPGDDQAVPGLHGVTGKSDVDVPGMIGVSSVDASSVDVSGVDGSGVSGGRSLDVLASQTTDSAGERSSAGIRPGSGVSSDAVFPETVTPGAGPGVGADPDGGAGSGGRESLPGAVTGEGGSFGVDVDVVVGRGDSHRQGGVVVSEGSAVLPVEGVVRSRGRRRGRAQAVSSLRKDGVAAWPEGLPVDAVRVLVPAEVVAGGGLAEFVQGVADSPGGPVLLVSQGDPTAGVVVTRGQGSALARDLGRHVVAMMPGQAGREPRWTVFPADGSRPKPLAGPGAAVLAGGRSGGVAGLADASATVLASAGGETVAGGEASAAQRASAQARSVVGYPRPGATTHAGQAGTGLPGPRSASWREQDLRRVDATAVEEESGDSGAVPWSADPVAVAQVAGMSSGADSAGVVERGLESMAGQLQRSSPVRGAGWSGGAGPGGAVVQPRRGGSRVAEQPGRASPGGEATGEGARRTSADPAAGVGRRRAWPGGVSANQARPAGNEPGGAGPKRAPEHVVGPDVVGPDAVGRDSGVWGVSDPVAEGGWVGSGYRFLSGVNQANYRCGDEGFRVNCLEAVVAFHNSVKFGRQFVAGPAVGDRDPARLEVAFGARARPVAGVAGVEWYVRVGWWVWLCR
>NZ_CP040605.1|WP_168584151.1|8026989_8027358_-|hypothetical-protein
MVKAAADRVAELEEREQLTDEQEKELAALRPKAQQWQKHKERDANRYRVGKAAADRVAELEELEELEEREQLTEGQAAELTVLRPKAQQWQNIRNIPRSISGWERLLPIVLRSWRSWRSGSS
>NZ_CP040605.1|WP_168590641.1|8016751_8017288_-|hypothetical-protein
MSSDAFHVTSPPPNGEGLARAMTMALEDAGVCPEDVDYVNGHGTGTPANDTAELAVMGAVFGASAPPFSSSKPQLGHTLGAAGVVETAIIALTVRDQVVGRGTSCRHFPVGARPAAWGSPVSTSRSRNTPYVLVIHQLFRVVRSWSPVGHRRLYGQASLTYTIGKTVVRTGRLCLTFG
>NZ_CP040605.1|WP_168589688.1|8015404_8016679_-|hypothetical-protein
MNEVAERARTWLHDTYGQRVVLRDEEAILSTERVAFFGCRYVESDEPMLAATICVPLDGADPFPASNAGPLDEALNVSRREPGAWRWRVNARNCVIATDAAVNCWPASALPWDPAGETPGWWDRMLAAYFPDAEVLICSTWADASRAIVDGGVGTRAVVWLRRQLGGRELAGHLLYADYADDAVVFLDGLRGAVAEQNDAEVAELVVARFRRRQDESVGGLLPWEVAADEFAGAVEKAEAWLGYRYDGEVELVGPDPADETERGWLFACTTRSFQDSGDWRDQMLDAAVVVPKSAGEEPFGLPNRDPWTWLDDWNAGKPGLMPPPEPAQAAWFGPMVAQLGPVVGVSVHEHWFGVLEEIASLPAQTQVLVWLRRRDTRGRESVGHLLVAVNDTDGVRLFDPMDGRAQPLIETAPFEFRVMRFDS
>NZ_CP040605.1|WP_168589687.1|8014107_8014677_-|hypothetical-protein
MLWTKTREPTCSGPGRPSGYGAGAARTVQLSISPENFTSPENFTAGIETVHYLTNLPPTFASPAGPAELVQGHWGTTNRLHLMRDVAFDEDRHRARTGYAPPNLAVLRNTAITLHRQAGATGIQTPLRAGNRRPERLPGPTARNDLNRTGRPCARHELAAAVDVDTSKQGAGGQQEMAKRATMRRSVSA
>NZ_CP040605.1|WP_168589686.1|8009679_8013234_-|hypothetical-protein
MAAIVVERAGASVLVRAGGARDPRLAFADKVAAEDHRKAVVVDQMGYAALHAHDSEVLTDLSGALSRGRGRRRDNVRLVASGSGRANPDGTPPLAARLARQLGVEVIAPDGELVILRGGELFSAGPGAGWVRFRRGRMTKRDGPRFPAPPWESELPEDFAAQTTDRTSVVAIPAGLWVRTANTRPAPLFDSGFGVPPDDRLRIVVGAPGEKVPDVADVARIVESLPVSVRHNFVLTVYGPEPVGPVPFAQQLAAYLGVPVRASHGMPYYAEAGARGMVAINRAGYPTWRPFLHESMYLPHGAPTPCSGVAPAPGLHGAGPGRYWLTEGWLVDLIPCGFLVRPATATPEAVATRLPVDPDHVNLIVTAVTRASDEVPARALAAIEKFARSLPEDAQQRLRLVASHWVHPGSLVGLGGALRVPMHVLTPAGPKPHRATSEKAGAPQKAGAPQNAAAPEKAAAPQNAAAPPETGAPQNAAAPPETGAPQKAAAPPEAALPQKAAVPPEAAVPPEAGAPPEAAAPQKAAVPPEAAAATIRLDQLSPAKTDRPADHQVPSGPELPATAEPEAQRSTSPLPQGSPAVGRPKAVGGGPDAAVPTRGRPTAGGARDVRSPQPPAHRDPAPVTVDHRGRIRPVGTSWQRRRRSGSGTPDPVTSESPLPAESSRFSPADDSPVPPASLPPAPSVSGLALSSSTFAIPPVARPDHDAQQDSQAPVSANAAGGSPADTGRTEPRLGRYIAPEMHALRDFDDGPTLVLPIAPSVRAASAAGSAAVEPPLPTTEAWAAPVAPQEPMPPVAPESAAAAPTKSGAAAQAAQPVSDQKNATPIPDLSSVPEASPVPDLSSASDVQPETDLSSQPDPSPAPAPGPAEPEAAAVPAEQDPSPETAEPEAAAEPAEQAPSPEPAEHDPSPEPVEQDAAPEPAPAATPLLLADHVSTDEERRKFRASLGWRFDAATQMVTRMLAERPGMRAGGGTTEALTTELAAAQIFASSEQTEVVEAIRSGGGQIERSYLHCLAGGLRRLPSLQGVVVRGGPSDAAAVDDYVVGAELLEPAPMVARADPAVAVPGAVEVLIWSITSRRLAGLVEGARQTDVVFLPGTVFQVVDVDRTAAKPRVLLAEVTPGWDPTSESGERRASRIRKKLEAAAAARDGVREAEPDAEEEARFAALPGMPRTPVAVGAWSAS
>NZ_CP040605.1|WP_168589685.1|8008675_8009683_-|hypothetical-protein
MTDATSVVERKDLYELVLCFAGRVPDDGLAIMRTCLADGEEDQVVALLVTAVTTRGLALVQHEMELIQTLAAQHGVRTAELEKAALLAELPLPVAEFSTPPSDQDGMDQQDAIVVEAASRVGGLLGLWRVVRRSEDSEVRLYLGEVEPSSDVVELAAEAQHSLVESGVEPRIELFTEGTELTPYHEAALEKAELVWTAVPPPRLRLARTFDGADPARGPYFKPDHPRLPDADAARALSFLRAGETVLSSEARMDDVMEPGQAAPVPVSFRSDGTWIWSDSVIYYLERYQLSPEPDLVDHALTSTTPPSVLSHLTYHHVLAELFAPAPQESMWQAS
>NZ_CP040605.1|WP_168589684.1|8005268_8008691_-|AAA-family-ATPase
MAGKLINGGSTRSMLTVSATGPDCYRTIGDAVAAARAGDVISIQPGTYRESVVLHRDVTLSAAGPAGAVRIESSVDPAVQMTAESAALSGIVVVHSGTETSAIDVPSGRLRLDECTVEAESAAAVFVRGQAEVLAHACTFVNPGGAGLIVVERGGGSFDKCAWREMKNAAVVFRTAATPLLLDCTITDVNGSAVLAAERSRGTVRDCRIVRAGNPAVVIESGSTLQVTGTSIVETDGVGVLVASGATPLLEDCSIDDAAAQGIVLMQQAAPEMRRVQVRRPVGYGIHVLDGSAGAFTECEVSGSNDVGVFVGESHTEFNELRVEGSGATGILVSDSAKPSFSDIQIVSSGGCGIEVRGGASARLFGAVIEASAADGVLATERGRLSAEDLAVTGSEAVGVRASDGGHLDLRGVTVSGSTEVNILVADSEATLHGCDLSGAGQQGMLISSGSSVELTQTRAAASEGSGIEWAAGTTGSMSQCEASGNGGDGVVVASTEPINIRECLFESNGGAGLRISVRRDNLQLNGIESKRNKDPQSDTTGGGDSRLSEQLKQSGSTRSTKTLGKTADQEGKPESASRKFEGPLGGLLDELNSLVGLADVKREVEILTRLEQMAERRAAVGLPMPPMSRHLVFTGAPGTGKTTVARLYGKILAELGVLRTGQLVEVGRADLVASIVGGTALKTTECFEKALGGVLFIDEAYALSAGSGGGADFGREAIDTLVKLMEDHRDDVVVIVAGYTVEMRKFLASNPGLGSRFSRTIEFADYSSADLVTIVEGLCRANDFRLEFETREAALNYFEKLPRDEAFGNGRTARKVFEEMIGRQAYRLADVPDANAVEMTRLLPEDIGPLPGSGIGAGAAAADTEKVDALLNKLQQMVGLAEVKSEVSNMVDLLASARQRQAAGLPVPSLSRHLIFGGPPGTGKTTVARLYGEILASLGVLQRGQVIEVGRANLVGEYVGHTAQRTTDAFERARGGVLFIDEAYTLSSQRGSGNDFGREAIDTLVKLMEDHRDEVVVVAAGYEEQMEDFLAANPGLSSRFSHRVRFADYTNDELVTIVTQHAASAGYECTGPTVAALRAHFVAVPRGTSFGNGRYARQVMDEAVTRHAKRLRLTASPTLEDLCVLLPEDIPGLAEIVGT
>NZ_CP040605.1|WP_168589693.1|8041258_8042047_-|IS630-family-transposase
MFDEPGVVPGEGRNVSVGDERLVGLHGVLLGLTGRVSDEFLATARWQLAEGGIGRVAESVCQELAAGGVALTFRQMGVLAEFLADSATSMFSRIPTGDEQRVLAWHFTGSPAGSAGVGKTGKRFSVNAMCAIGNKGELYFTVYTGSFNGKVFLRFLDRLTRHLDRKVHLIVDGHPVHRRKTIQQWITKHAEAIEMHFLPGYSPELNPDEILNADLKRTMSTSTAPKTRDELKQAVRSFLHRLQKLPDRVRSYFGKPEVRYAA
>NZ_CP040605.1|WP_168590642.1|8042046_8043861_-|hypothetical-protein
MERHLRTMPPEYNPNGVREKTEAAKNLVWQGPWTPAQVQKVEEELPGVEAAVRVLRDARRAKVHEVYMQAKQAKAQRRVPITYFKDGVPGGVSSRPDARLGLEVEFKLPGENFDERVNSLGAELEREELVDWRTAHGSKLLPWMEDYEEILLDGRWALQEEAERFEVEATSPILRNDPKRPVSEQLWPSMEKLLSAVQRQGGYGSESGGHINVSFDWSLTPRQYVRVAQVVKVFEALLFRLGNVAGGDESKQRKVRNAGPISLPSDPYAVDDDTGDDGHESLPDPTERFRAVRFDVLGYEDDRLEFRVWAGDAGELTRNPALWQVRAELSAAIMLAGTDPAIYRELDRLMGDPDLLGYDDQTRDEGVWLEKLVEFLELLPLSEAGQAQVVQLFAWTRPWKLGDLEEGHLALVVSLPQQSLLFPAPDASKVQVIAEAYSYQLYKDASLVVARMTSDRSGIPLPNGKVIDLRLFARLLQTYYLGYGSYSEETWTLLAIPRASGALLAEVLRSVKGPVLATMSDVYRTPDGRLLTGVYERLKDGHVRFRPAREGWIEFTKNKDDPSQIDSRSTGKADVGDALMESSTRLYDKPAEVYRYWPTRGSGS
>NZ_CP040605.1|WP_168589694.1|8044271_8045108_-|hypothetical-protein
MLTPEEEGELDLRREIEAYTKKKNDLQKQARERNRAIADIKELEALPQSAEIKDRLERLREQVLGLPDVAESLKETKGRLAEKKEKLDGLGWIAGVGASGQQGEQDAMVLSGVSESAGAGREASPVGSDLGEWLAWANADLGVSGVAGSAESAGAGREASPDGGVEPFPEAVLEEDSAGVPAAPGAVPVGRWSDADVREEIKGARKLGLSSEEKDAVRLTVQSTHDPQKLRGAVSVDDVMALVAARGRGLDGDWARWRRFPGSWRSGWARSRRRAVAG
>NZ_CP040605.1|WP_168589695.1|8045101_8045842_-|hypothetical-protein
MGSRASKRRKAATTVAAGIDSGNQGGEGDGSAPTHQAEKDARIAERKRKKQEDNAKQLEAYKEAMARVAELKAERDKKRESGEELDSEEEEELAELEAKVEKRRQQWRKSSAELAQARKARKARVAELKAERERKRERGEELDSEEEKELAKLEPRVEKRQQQLRESGGRFNEKRTADNARVRQLTGKRERGEELDSEEEKELAERKLRVNKRQRQGRESKERNKKKARDEAAGLRSWRIGRSCGC

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP040605_1	1.1\|24027\|33\|NZ_CP040605\|CRISPRCasFinder	24027-24059	33	NZ_CP040605.1	110945-110977	0	1.0
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	250031-250053	0	1.0
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	1272835-1272857	0	1.0
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	1487183-1487205	0	1.0
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	1696258-1696280	0	1.0
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	1869624-1869646	0	1.0
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	2276732-2276754	0	1.0
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	2352172-2352194	0	1.0
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	2496433-2496455	0	1.0
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	2572400-2572422	0	1.0
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	2606643-2606665	0	1.0
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	3109751-3109773	0	1.0
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	3144996-3145018	0	1.0
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	3295039-3295061	0	1.0
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	3722403-3722425	0	1.0
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	4116640-4116662	0	1.0
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	5761872-5761894	0	1.0
NZ_CP040605_18	18.1\|5642268\|29\|NZ_CP040605\|CRISPRCasFinder	5642268-5642296	29	NZ_CP040605.1	5652190-5652218	0	1.0
NZ_CP040605_19	19.1\|5644760\|29\|NZ_CP040605\|CRISPRCasFinder	5644760-5644788	29	NZ_CP040605.1	5652190-5652218	0	1.0
NZ_CP040605_21	21.1\|5649719\|34\|NZ_CP040605\|CRISPRCasFinder	5649719-5649752	34	NZ_CP040605.1	5652190-5652223	0	1.0
NZ_CP040605_23	23.1\|7947963\|27\|NZ_CP040605\|CRISPRCasFinder	7947963-7947989	27	NZ_CP040605.1	53254-53280	0	1.0
NZ_CP040605_24	24.1\|8037695\|33\|NZ_CP040605\|CRISPRCasFinder	8037695-8037727	33	NZ_CP040605.1	110918-110950	0	1.0
NZ_CP040605_24	24.1\|8037695\|33\|NZ_CP040605\|CRISPRCasFinder	8037695-8037727	33	NZ_CP040605.1	5636859-5636891	0	1.0
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	288502-288524	1	0.957
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	746846-746868	1	0.957
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	811038-811060	1	0.957
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	1002280-1002302	1	0.957
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	1055082-1055104	1	0.957
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	2199775-2199797	1	0.957
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	2680802-2680824	1	0.957
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	2842642-2842664	1	0.957
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	2929973-2929995	1	0.957
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	3027072-3027094	1	0.957
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	3052764-3052786	1	0.957
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	3492264-3492286	1	0.957
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	4521911-4521933	1	0.957
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	4529854-4529876	1	0.957
NZ_CP040605_14	14.1\|3393049\|34\|NZ_CP040605\|CRISPRCasFinder	3393049-3393082	34	NZ_CP040605.1	7453356-7453389	1	0.971
NZ_CP040605_15	15.1\|3658934\|28\|NZ_CP040605\|CRISPRCasFinder	3658934-3658961	28	NZ_CP040605.1	53269-53296	1	0.964
NZ_CP040605_16	16.1\|3837694\|34\|NZ_CP040605\|CRISPRCasFinder	3837694-3837727	34	NZ_CP040605.1	8037722-8037755	1	0.971
NZ_CP040605_20	20.1\|5647238\|34\|NZ_CP040605\|CRISPRCasFinder	5647238-5647271	34	NZ_CP040605.1	5652190-5652223	1	0.971
NZ_CP040605_23	23.1\|7947963\|27\|NZ_CP040605\|CRISPRCasFinder	7947963-7947989	27	NZ_CP040605.1	4172960-4172986	1	0.963
NZ_CP040605_23	23.1\|7947963\|27\|NZ_CP040605\|CRISPRCasFinder	7947963-7947989	27	NZ_CP040605.1	4173019-4173045	1	0.963
NZ_CP040605_23	23.1\|7947963\|27\|NZ_CP040605\|CRISPRCasFinder	7947963-7947989	27	NZ_CP040605.1	7050379-7050405	1	0.963
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	621843-621865	2	0.913
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	794913-794935	2	0.913
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	902784-902806	2	0.913
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	934928-934950	2	0.913
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	978603-978625	2	0.913
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	1108768-1108790	2	0.913
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	1139699-1139721	2	0.913
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	1197057-1197079	2	0.913
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	2075240-2075262	2	0.913
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	2185000-2185022	2	0.913
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	2510901-2510923	2	0.913
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	2837128-2837150	2	0.913
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	3437411-3437433	2	0.913
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	3692342-3692364	2	0.913
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	3867287-3867309	2	0.913
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	4358604-4358626	2	0.913
NZ_CP040605_8	8.1\|1547802\|59\|NZ_CP040605\|CRISPRCasFinder	1547802-1547860	59	NZ_CP040605.1	2496446-2496504	2	0.966
NZ_CP040605_10	10.1\|1889857\|27\|NZ_CP040605\|CRISPRCasFinder	1889857-1889883	27	NZ_CP040605.1	1889893-1889919	2	0.926
NZ_CP040605_16	16.1\|3837694\|34\|NZ_CP040605\|CRISPRCasFinder	3837694-3837727	34	NZ_CP040605.1	5636831-5636864	2	0.941
NZ_CP040605_16	16.1\|3837694\|34\|NZ_CP040605\|CRISPRCasFinder	3837694-3837727	34	NZ_CP040605.1	110945-110978	2	0.941
NZ_CP040605_21	21.1\|5649719\|34\|NZ_CP040605\|CRISPRCasFinder	5649719-5649752	34	NZ_CP040605.1	5654650-5654683	2	0.941
NZ_CP040605_23	23.1\|7947963\|27\|NZ_CP040605\|CRISPRCasFinder	7947963-7947989	27	NZ_CP040605.1	249740-249766	2	0.926
NZ_CP040605_23	23.1\|7947963\|27\|NZ_CP040605\|CRISPRCasFinder	7947963-7947989	27	NZ_CP040605.1	249799-249825	2	0.926
NZ_CP040605_23	23.1\|7947963\|27\|NZ_CP040605\|CRISPRCasFinder	7947963-7947989	27	NZ_CP040605.1	633427-633453	2	0.926
NZ_CP040605_23	23.1\|7947963\|27\|NZ_CP040605\|CRISPRCasFinder	7947963-7947989	27	NZ_CP040605.1	693083-693109	2	0.926
NZ_CP040605_23	23.1\|7947963\|27\|NZ_CP040605\|CRISPRCasFinder	7947963-7947989	27	NZ_CP040605.1	2959834-2959860	2	0.926
NZ_CP040605_23	23.1\|7947963\|27\|NZ_CP040605\|CRISPRCasFinder	7947963-7947989	27	NZ_CP040605.1	2959893-2959919	2	0.926
NZ_CP040605_23	23.1\|7947963\|27\|NZ_CP040605\|CRISPRCasFinder	7947963-7947989	27	NZ_CP040605.1	5681081-5681107	2	0.926
NZ_CP040605_23	23.1\|7947963\|27\|NZ_CP040605\|CRISPRCasFinder	7947963-7947989	27	NZ_CP040605.1	5681140-5681166	2	0.926
NZ_CP040605_23	23.1\|7947963\|27\|NZ_CP040605\|CRISPRCasFinder	7947963-7947989	27	NZ_CP040605.1	7500272-7500298	2	0.926
NZ_CP040605_23	23.1\|7947963\|27\|NZ_CP040605\|CRISPRCasFinder	7947963-7947989	27	NZ_CP040605.1	7500331-7500357	2	0.926
NZ_CP040605_23	23.1\|7947963\|27\|NZ_CP040605\|CRISPRCasFinder	7947963-7947989	27	NZ_CP040605.1	7500390-7500416	2	0.926
NZ_CP040605_23	23.1\|7947963\|27\|NZ_CP040605\|CRISPRCasFinder	7947963-7947989	27	NZ_CP040605.1	7582367-7582393	2	0.926
NZ_CP040605_23	23.1\|7947963\|27\|NZ_CP040605\|CRISPRCasFinder	7947963-7947989	27	NZ_CP040605.1	7687371-7687397	2	0.926
NZ_CP040605_23	23.1\|7947963\|27\|NZ_CP040605\|CRISPRCasFinder	7947963-7947989	27	NZ_CP040605.1	7687430-7687456	2	0.926
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	573628-573650	9	0.609
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	1547884-1547906	9	0.609
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	1713588-1713610	9	0.609
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	1919711-1919733	9	0.609
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	2960112-2960134	9	0.609
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	3096769-3096791	9	0.609
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	4050159-4050181	9	0.609
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP040605.1	4263746-4263768	9	0.609

1. spacer 1.1|24027|33|NZ_CP040605|CRISPRCasFinder matches to position: 110945-110977, mismatch: 0, identity: 1.0

ccgggtcaacacccggtaccccaccggaatacg	CRISPR spacer
ccgggtcaacacccggtaccccaccggaatacg	Protospacer
*********************************

2. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 250031-250053, mismatch: 0, identity: 1.0

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaatcgaaggtc	Protospacer
***********************

3. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 1272835-1272857, mismatch: 0, identity: 1.0

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaatcgaaggtc	Protospacer
***********************

4. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 1487183-1487205, mismatch: 0, identity: 1.0

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaatcgaaggtc	Protospacer
***********************

5. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 1696258-1696280, mismatch: 0, identity: 1.0

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaatcgaaggtc	Protospacer
***********************

6. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 1869624-1869646, mismatch: 0, identity: 1.0

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaatcgaaggtc	Protospacer
***********************

7. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 2276732-2276754, mismatch: 0, identity: 1.0

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaatcgaaggtc	Protospacer
***********************

8. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 2352172-2352194, mismatch: 0, identity: 1.0

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaatcgaaggtc	Protospacer
***********************

9. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 2496433-2496455, mismatch: 0, identity: 1.0

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaatcgaaggtc	Protospacer
***********************

10. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 2572400-2572422, mismatch: 0, identity: 1.0

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaatcgaaggtc	Protospacer
***********************

11. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 2606643-2606665, mismatch: 0, identity: 1.0

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaatcgaaggtc	Protospacer
***********************

12. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 3109751-3109773, mismatch: 0, identity: 1.0

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaatcgaaggtc	Protospacer
***********************

13. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 3144996-3145018, mismatch: 0, identity: 1.0

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaatcgaaggtc	Protospacer
***********************

14. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 3295039-3295061, mismatch: 0, identity: 1.0

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaatcgaaggtc	Protospacer
***********************

15. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 3722403-3722425, mismatch: 0, identity: 1.0

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaatcgaaggtc	Protospacer
***********************

16. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 4116640-4116662, mismatch: 0, identity: 1.0

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaatcgaaggtc	Protospacer
***********************

17. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 5761872-5761894, mismatch: 0, identity: 1.0

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaatcgaaggtc	Protospacer
***********************

18. spacer 18.1|5642268|29|NZ_CP040605|CRISPRCasFinder matches to position: 5652190-5652218, mismatch: 0, identity: 1.0

tccaccgtgatcgcggcaggcaggtggag	CRISPR spacer
tccaccgtgatcgcggcaggcaggtggag	Protospacer
*****************************

19. spacer 19.1|5644760|29|NZ_CP040605|CRISPRCasFinder matches to position: 5652190-5652218, mismatch: 0, identity: 1.0

tccaccgtgatcgcggcaggcaggtggag	CRISPR spacer
tccaccgtgatcgcggcaggcaggtggag	Protospacer
*****************************

20. spacer 21.1|5649719|34|NZ_CP040605|CRISPRCasFinder matches to position: 5652190-5652223, mismatch: 0, identity: 1.0

tccaccgtgatcgcggcaggcaggtggaggcgcg	CRISPR spacer
tccaccgtgatcgcggcaggcaggtggaggcgcg	Protospacer
**********************************

21. spacer 23.1|7947963|27|NZ_CP040605|CRISPRCasFinder matches to position: 53254-53280, mismatch: 0, identity: 1.0

gccggttcttaccggaaccaccactca	CRISPR spacer
gccggttcttaccggaaccaccactca	Protospacer
***************************

22. spacer 24.1|8037695|33|NZ_CP040605|CRISPRCasFinder matches to position: 110918-110950, mismatch: 0, identity: 1.0

gtgcgggtagcggtgtgcccggccggtccgggt	CRISPR spacer
gtgcgggtagcggtgtgcccggccggtccgggt	Protospacer
*********************************

23. spacer 24.1|8037695|33|NZ_CP040605|CRISPRCasFinder matches to position: 5636859-5636891, mismatch: 0, identity: 1.0

gtgcgggtagcggtgtgcccggccggtccgggt	CRISPR spacer
gtgcgggtagcggtgtgcccggccggtccgggt	Protospacer
*********************************

24. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 288502-288524, mismatch: 1, identity: 0.957

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaatcgaagctc	Protospacer
******************** **

25. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 746846-746868, mismatch: 1, identity: 0.957

aatttccattgaaatcgaaggtc	CRISPR spacer
aagttccattgaaatcgaaggtc	Protospacer
** ********************

26. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 811038-811060, mismatch: 1, identity: 0.957

aatttccattgaaatcgaaggtc	CRISPR spacer
aagttccattgaaatcgaaggtc	Protospacer
** ********************

27. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 1002280-1002302, mismatch: 1, identity: 0.957

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccatggaaatcgaaggtc	Protospacer
********* *************

28. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 1055082-1055104, mismatch: 1, identity: 0.957

aatttccattgaaatcgaaggtc	CRISPR spacer
aagttccattgaaatcgaaggtc	Protospacer
** ********************

29. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 2199775-2199797, mismatch: 1, identity: 0.957

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaattgaaggtc	Protospacer
***************.*******

30. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 2680802-2680824, mismatch: 1, identity: 0.957

aatttccattgaaatcgaaggtc	CRISPR spacer
aagttccattgaaatcgaaggtc	Protospacer
** ********************

31. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 2842642-2842664, mismatch: 1, identity: 0.957

aatttccattgaaatcgaaggtc	CRISPR spacer
aagttccattgaaatcgaaggtc	Protospacer
** ********************

32. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 2929973-2929995, mismatch: 1, identity: 0.957

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaatcgaagatc	Protospacer
********************.**

33. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 3027072-3027094, mismatch: 1, identity: 0.957

aatttccattgaaatcgaaggtc	CRISPR spacer
aagttccattgaaatcgaaggtc	Protospacer
** ********************

34. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 3052764-3052786, mismatch: 1, identity: 0.957

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccatggaaatcgaaggtc	Protospacer
********* *************

35. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 3492264-3492286, mismatch: 1, identity: 0.957

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaatcgaatgtc	Protospacer
******************* ***

36. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 4521911-4521933, mismatch: 1, identity: 0.957

aatttccattgaaatcgaaggtc	CRISPR spacer
aacttccattgaaatcgaaggtc	Protospacer
**.********************

37. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 4529854-4529876, mismatch: 1, identity: 0.957

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaatcgaatgtc	Protospacer
******************* ***

38. spacer 14.1|3393049|34|NZ_CP040605|CRISPRCasFinder matches to position: 7453356-7453389, mismatch: 1, identity: 0.971

gcatatcccggtggggtaccgggtgttggtccgg	CRISPR spacer
gcatattccggtggggtaccgggtgttggtccgg	Protospacer
******.***************************

39. spacer 15.1|3658934|28|NZ_CP040605|CRISPRCasFinder matches to position: 53269-53296, mismatch: 1, identity: 0.964

ggacgggcatcggtcgtgagtggttgtt	CRISPR spacer
ggacgggcatcggtcgtgagtggtggtt	Protospacer
************************ ***

40. spacer 16.1|3837694|34|NZ_CP040605|CRISPRCasFinder matches to position: 8037722-8037755, mismatch: 1, identity: 0.971

gcatatcccggtggggtaccgggtgttgacccgg	CRISPR spacer
gcatattccggtggggtaccgggtgttgacccgg	Protospacer
******.***************************

41. spacer 20.1|5647238|34|NZ_CP040605|CRISPRCasFinder matches to position: 5652190-5652223, mismatch: 1, identity: 0.971

tccaccgtgatcgcggcaggcaggtggaggtgcg	CRISPR spacer
tccaccgtgatcgcggcaggcaggtggaggcgcg	Protospacer
******************************.***

42. spacer 23.1|7947963|27|NZ_CP040605|CRISPRCasFinder matches to position: 4172960-4172986, mismatch: 1, identity: 0.963

gccggttcttaccggaaccaccactca	CRISPR spacer
gccggctcttaccggaaccaccactca	Protospacer
*****.*********************

43. spacer 23.1|7947963|27|NZ_CP040605|CRISPRCasFinder matches to position: 4173019-4173045, mismatch: 1, identity: 0.963

gccggttcttaccggaaccaccactca	CRISPR spacer
gccggctcttaccggaaccaccactca	Protospacer
*****.*********************

44. spacer 23.1|7947963|27|NZ_CP040605|CRISPRCasFinder matches to position: 7050379-7050405, mismatch: 1, identity: 0.963

gccggttcttaccggaaccaccactca	CRISPR spacer
gccggttcttaccggaaccatcactca	Protospacer
********************.******

45. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 621843-621865, mismatch: 2, identity: 0.913

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttcaatggaaatcgaaggtc	Protospacer
****** ** *************

46. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 794913-794935, mismatch: 2, identity: 0.913

aatttccattgaaatcgaaggtc	CRISPR spacer
aagttccattgaaatcgaagatc	Protospacer
** *****************.**

47. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 902784-902806, mismatch: 2, identity: 0.913

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttcaatggaaatcgaaggtc	Protospacer
****** ** *************

48. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 934928-934950, mismatch: 2, identity: 0.913

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttcaatggaaatcgaaggtc	Protospacer
****** ** *************

49. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 978603-978625, mismatch: 2, identity: 0.913

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttcaatggaaatcgaaggtc	Protospacer
****** ** *************

50. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 1108768-1108790, mismatch: 2, identity: 0.913

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaattgaagctc	Protospacer
***************.**** **

51. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 1139699-1139721, mismatch: 2, identity: 0.913

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttcaatggaaatcgaaggtc	Protospacer
****** ** *************

52. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 1197057-1197079, mismatch: 2, identity: 0.913

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttcaatggaaatcgaaggtc	Protospacer
****** ** *************

53. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 2075240-2075262, mismatch: 2, identity: 0.913

aatttccattgaaatcgaaggtc	CRISPR spacer
aagttccattgaaatcgaatgtc	Protospacer
** **************** ***

54. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 2185000-2185022, mismatch: 2, identity: 0.913

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttcaatggaaatcgaaggtc	Protospacer
****** ** *************

55. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 2510901-2510923, mismatch: 2, identity: 0.913

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttcaatggaaatcgaaggtc	Protospacer
****** ** *************

56. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 2837128-2837150, mismatch: 2, identity: 0.913

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttcaattgaaatcggaggtc	Protospacer
****** **********.*****

57. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 3437411-3437433, mismatch: 2, identity: 0.913

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttcaatggaaatcgaaggtc	Protospacer
****** ** *************

58. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 3692342-3692364, mismatch: 2, identity: 0.913

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccatggaaatcggaggtc	Protospacer
********* *******.*****

59. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 3867287-3867309, mismatch: 2, identity: 0.913

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccattgaaatcagaggtc	Protospacer
****************..*****

60. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 4358604-4358626, mismatch: 2, identity: 0.913

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttcaatggaaatcgaaggtc	Protospacer
****** ** *************

61. spacer 8.1|1547802|59|NZ_CP040605|CRISPRCasFinder matches to position: 2496446-2496504, mismatch: 2, identity: 0.966

aatggaaattgcggatgatcggcgtgtcgcaccacgacacgccgacgcctgtggacaac	CRISPR spacer
aatggaaattgcggatgatcggcgtgtcgcaccccgacacgccgacggctgtggacaac	Protospacer
********************************* ************* ***********

62. spacer 10.1|1889857|27|NZ_CP040605|CRISPRCasFinder matches to position: 1889893-1889919, mismatch: 2, identity: 0.926

cgggtactgctactgcggcgggtactg	CRISPR spacer
cgggtactgctgctggggcgggtactg	Protospacer
***********.*** ***********

63. spacer 16.1|3837694|34|NZ_CP040605|CRISPRCasFinder matches to position: 5636831-5636864, mismatch: 2, identity: 0.941

gcatatcccggtggggtaccgggtgttgacccgg	CRISPR spacer
gcatattccagtggggtaccgggtgttgacccgg	Protospacer
******.**.************************

64. spacer 16.1|3837694|34|NZ_CP040605|CRISPRCasFinder matches to position: 110945-110978, mismatch: 2, identity: 0.941

gcatatcccggtggggtaccgggtgttgacccgg	CRISPR spacer
gcgtattccggtggggtaccgggtgttgacccgg	Protospacer
**.***.***************************

65. spacer 21.1|5649719|34|NZ_CP040605|CRISPRCasFinder matches to position: 5654650-5654683, mismatch: 2, identity: 0.941

tccaccgtgatcgcggcaggcaggtggaggcgcg	CRISPR spacer
tccaccgttatcgcggcaggcaggtggatgcgcg	Protospacer
******** ******************* *****

66. spacer 23.1|7947963|27|NZ_CP040605|CRISPRCasFinder matches to position: 249740-249766, mismatch: 2, identity: 0.926

gccggttcttaccggaaccaccactca	CRISPR spacer
gccggttcttaccggaacaaacactca	Protospacer
****************** * ******

67. spacer 23.1|7947963|27|NZ_CP040605|CRISPRCasFinder matches to position: 249799-249825, mismatch: 2, identity: 0.926

gccggttcttaccggaaccaccactca	CRISPR spacer
gccggttcttaccggaacaaacactca	Protospacer
****************** * ******

68. spacer 23.1|7947963|27|NZ_CP040605|CRISPRCasFinder matches to position: 633427-633453, mismatch: 2, identity: 0.926

gccggttcttaccggaaccaccactca	CRISPR spacer
gccggttcttaccggaacgagcactca	Protospacer
****************** * ******

69. spacer 23.1|7947963|27|NZ_CP040605|CRISPRCasFinder matches to position: 693083-693109, mismatch: 2, identity: 0.926

gccggttcttaccggaaccaccactca	CRISPR spacer
gccggttcttaccggaacgaacactca	Protospacer
****************** * ******

70. spacer 23.1|7947963|27|NZ_CP040605|CRISPRCasFinder matches to position: 2959834-2959860, mismatch: 2, identity: 0.926

gccggttcttaccggaaccaccactca	CRISPR spacer
gccggttcttaccggaacaatcactca	Protospacer
****************** *.******

71. spacer 23.1|7947963|27|NZ_CP040605|CRISPRCasFinder matches to position: 2959893-2959919, mismatch: 2, identity: 0.926

gccggttcttaccggaaccaccactca	CRISPR spacer
gccggttcttaccggaacaatcactca	Protospacer
****************** *.******

72. spacer 23.1|7947963|27|NZ_CP040605|CRISPRCasFinder matches to position: 5681081-5681107, mismatch: 2, identity: 0.926

gccggttcttaccggaaccaccactca	CRISPR spacer
gccggttcttaccggaacaatcactca	Protospacer
****************** *.******

73. spacer 23.1|7947963|27|NZ_CP040605|CRISPRCasFinder matches to position: 5681140-5681166, mismatch: 2, identity: 0.926

gccggttcttaccggaaccaccactca	CRISPR spacer
gccggttcttaccggaacaatcactca	Protospacer
****************** *.******

74. spacer 23.1|7947963|27|NZ_CP040605|CRISPRCasFinder matches to position: 7500272-7500298, mismatch: 2, identity: 0.926

gccggttcttaccggaaccaccactca	CRISPR spacer
gccggttcttaccggaacaatcactca	Protospacer
****************** *.******

75. spacer 23.1|7947963|27|NZ_CP040605|CRISPRCasFinder matches to position: 7500331-7500357, mismatch: 2, identity: 0.926

gccggttcttaccggaaccaccactca	CRISPR spacer
gccggttcttaccggaacaatcactca	Protospacer
****************** *.******

76. spacer 23.1|7947963|27|NZ_CP040605|CRISPRCasFinder matches to position: 7500390-7500416, mismatch: 2, identity: 0.926

gccggttcttaccggaaccaccactca	CRISPR spacer
gccggttcttaccggaacagccactca	Protospacer
****************** .*******

77. spacer 23.1|7947963|27|NZ_CP040605|CRISPRCasFinder matches to position: 7582367-7582393, mismatch: 2, identity: 0.926

gccggttcttaccggaaccaccactca	CRISPR spacer
gccggttcttaccggaacagccactca	Protospacer
****************** .*******

78. spacer 23.1|7947963|27|NZ_CP040605|CRISPRCasFinder matches to position: 7687371-7687397, mismatch: 2, identity: 0.926

gccggttcttaccggaaccaccactca	CRISPR spacer
gccggctcttaccggaaccatcactca	Protospacer
*****.**************.******

79. spacer 23.1|7947963|27|NZ_CP040605|CRISPRCasFinder matches to position: 7687430-7687456, mismatch: 2, identity: 0.926

gccggttcttaccggaaccaccactca	CRISPR spacer
gccggctcttaccggaaccatcactca	Protospacer
*****.**************.******

80. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 573628-573650, mismatch: 9, identity: 0.609

-------aatttccattgaaatcgaaggtc	CRISPR spacer
gaccttcgatttccattgaaatt-------	Protospacer
       .**************.

81. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 1547884-1547906, mismatch: 9, identity: 0.609

-------aatttccattgaaatcgaaggtc	CRISPR spacer
gaccttcgatttccattgaaatt-------	Protospacer
       .**************.

82. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 1713588-1713610, mismatch: 9, identity: 0.609

-------aatttccattgaaatcgaaggtc	CRISPR spacer
gaccttcgatttccattgaaatt-------	Protospacer
       .**************.

83. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 1919711-1919733, mismatch: 9, identity: 0.609

-------aatttccattgaaatcgaaggtc	CRISPR spacer
gaccttcgatttccattgaaatt-------	Protospacer
       .**************.

84. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 2960112-2960134, mismatch: 9, identity: 0.609

-------aatttccattgaaatcgaaggtc	CRISPR spacer
gaccttcgatttccattgaaatt-------	Protospacer
       .**************.

85. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 3096769-3096791, mismatch: 9, identity: 0.609

-------aatttccattgaaatcgaaggtc	CRISPR spacer
gaccttcgatttccattgaaatt-------	Protospacer
       .**************.

86. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 4050159-4050181, mismatch: 9, identity: 0.609

-------aatttccattgaaatcgaaggtc	CRISPR spacer
gaccttcgatttccattgaaatt-------	Protospacer
       .**************.

87. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to position: 4263746-4263768, mismatch: 9, identity: 0.609

-------aatttccattgaaatcgaaggtc	CRISPR spacer
gaccttcgatttccattgaaatt-------	Protospacer
       .**************.

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP040605_4	4.1\|583712\|23\|NZ_CP040605\|CRISPRCasFinder	583712-583734	23	NZ_CP009649	Bacillus pseudomycoides strain BTZ plasmid pBTZ_2, complete sequence	22227-22249	2	0.913
NZ_CP040605_22	22.2\|5907345\|23\|NZ_CP040605\|CRISPRCasFinder	5907345-5907367	23	NZ_CP020447	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed7, complete sequence	143103-143125	2	0.913
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_MF133496	Klebsiella pneumoniae strain 675920 plasmid p675920-2, complete sequence	40-62	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_CP033957	Klebsiella pneumoniae strain L39_2 plasmid p4_L39, complete sequence	74218-74240	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_CP024461	Klebsiella pneumoniae strain QS17-0161 plasmid pMR0617tem, complete sequence	17786-17808	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	AP022370	Klebsiella pneumoniae E328 plasmid pE328_IMP6 DNA, complete sequence	52241-52263	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_CP028480	Klebsiella pneumoniae strain 2e plasmid unnamed2	37301-37323	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_CP035208	Klebsiella quasipneumoniae strain TH114 plasmid pTH114-3, complete sequence	51401-51423	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_CP035213	Klebsiella pneumoniae strain TH164 plasmid pTH164-3, complete sequence	51530-51552	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_CP054747	Klebsiella pneumoniae strain KP20194c4 plasmid pKP20194c4-p3, complete sequence	38143-38165	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_CP054723	Klebsiella pneumoniae strain KP20194f plasmid pKP20194f-p3, complete sequence	27578-27600	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	CP050279	Klebsiella pneumoniae strain 10553 plasmid unnamed4, complete sequence	57989-58011	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_CP023985	Klebsiella variicola strain X39 plasmid pX39-8, complete sequence	64287-64309	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_MF190368	Klebsiella pneumoniae strain 205880 plasmid p205880-qnrS, complete sequence	40-62	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_MG288684	Klebsiella aerogenes strain E20 plasmid pE20-qnrS, complete sequence	75517-75539	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	MT035876	Klebsiella pneumoniae strain KP18-3-8 plasmid pKP18-3-8-IncFII, complete sequence	48708-48730	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	MT090960	Klebsiella pneumoniae strain KP18-2079 plasmid pKP18-2079_tetA, complete sequence	13915-13937	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_CP033775	Klebsiella pneumoniae strain FDAARGOS_531 plasmid unnamed2, complete sequence	35056-35078	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_CP031261	Klebsiella quasipneumoniae strain L22 plasmid pL22-4, complete sequence	13075-13097	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_CP041095	Klebsiella pneumoniae subsp. pneumoniae strain KPCTRSRTH01 plasmid unnamed3, complete sequence	4926-4948	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_CP041376	Klebsiella pneumoniae strain KP58 plasmid pKP58-3, complete sequence	68090-68112	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_CP032243	Klebsiella pneumoniae strain XJ-K2 plasmid unnamed3, complete sequence	16231-16253	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_CP047195	Klebsiella pneumoniae strain Kp36 plasmid unnamed3, complete sequence	32711-32733	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_CP029382	Klebsiella pneumoniae subsp. pneumoniae strain SCKP020079 plasmid pQnrS1_020079, complete sequence	19168-19190	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_CP034126	Klebsiella pneumoniae strain BJCFK909 plasmid p3s1, complete sequence	16832-16854	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_CP018341	Klebsiella pneumoniae isolate Kp_Goe_154414 plasmid pKp_Goe_414-4, complete sequence	61774-61796	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	CP050283	Klebsiella pneumoniae strain 9949 plasmid unnamed3, complete sequence	42291-42313	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_CP054765	Klebsiella pneumoniae strain KP20194b2 plasmid pKP20194b2-p3, complete sequence	17070-17092	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_CP054735	Klebsiella pneumoniae strain KP20194d plasmid pKP20194d-p3, complete sequence	57525-57547	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	CP050288	Klebsiella pneumoniae strain 9630 plasmid unnamed3, complete sequence	75142-75164	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_MH341574	Klebsiella pneumoniae strain MYKLB95 plasmid MYKLB95-1, complete sequence	1774-1796	3	0.87
NZ_CP040605_6	6.2\|1507013\|23\|NZ_CP040605\|CRISPRCasFinder	1507013-1507035	23	NZ_CP035205	Klebsiella pneumoniae strain LH94 plasmid pLH94-3, complete sequence	1944-1966	3	0.87
NZ_CP040605_5	5.3\|1451473\|27\|NZ_CP040605\|CRISPRCasFinder	1451473-1451499	27	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	162778-162804	5	0.815
NZ_CP040605_5	5.3\|1451473\|27\|NZ_CP040605\|CRISPRCasFinder	1451473-1451499	27	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	633226-633252	5	0.815
NZ_CP040605_7	7.1\|1510996\|27\|NZ_CP040605\|CRISPRCasFinder	1510996-1511022	27	NZ_CP020613	Paracoccus contaminans strain RKI 16-01929T=LMG 29738T=CCM 8701T=CIP 111112T plasmid unnamed, complete sequence	55293-55319	5	0.815
NZ_CP040605_7	7.4\|1511160\|28\|NZ_CP040605\|CRISPRCasFinder	1511160-1511187	28	NZ_CP020539	Sphingobium herbicidovorans strain MH plasmid pMSHV, complete sequence	26491-26518	5	0.821
NZ_CP040605_10	10.1\|1889857\|27\|NZ_CP040605\|CRISPRCasFinder	1889857-1889883	27	NZ_AP019741	Acinetobacter radioresistens DSM 6976 = NBRC 102413 = CIP 103788 strain NBRC 102413 plasmid pARA1, complete sequence	128428-128454	5	0.815
NZ_CP040605_10	10.1\|1889857\|27\|NZ_CP040605\|CRISPRCasFinder	1889857-1889883	27	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	722237-722263	5	0.815
NZ_CP040605_7	7.1\|1510996\|27\|NZ_CP040605\|CRISPRCasFinder	1510996-1511022	27	NZ_CP040763	Paracoccus sp. 2251 plasmid unnamed4, complete sequence	175516-175542	6	0.778
NZ_CP040605_7	7.1\|1510996\|27\|NZ_CP040605\|CRISPRCasFinder	1510996-1511022	27	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	529439-529465	6	0.778
NZ_CP040605_7	7.4\|1511160\|28\|NZ_CP040605\|CRISPRCasFinder	1511160-1511187	28	NZ_CP023440	Thauera sp. K11 plasmid pTX1, complete sequence	106180-106207	6	0.786
NZ_CP040605_7	7.9\|1510995\|34\|NZ_CP040605\|CRT	1510995-1511028	34	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	529438-529471	6	0.824
NZ_CP040605_18	18.1\|5642268\|29\|NZ_CP040605\|CRISPRCasFinder	5642268-5642296	29	NZ_CP021409	Celeribacter manganoxidans strain DY25 plasmid pDY25-E, complete sequence	58698-58726	6	0.793
NZ_CP040605_18	18.1\|5642268\|29\|NZ_CP040605\|CRISPRCasFinder	5642268-5642296	29	NZ_CP020471	Rhodobacter blasticus strain 28/5 plasmid pRsa, complete sequence	3368-3396	6	0.793
NZ_CP040605_19	19.1\|5644760\|29\|NZ_CP040605\|CRISPRCasFinder	5644760-5644788	29	NZ_CP021409	Celeribacter manganoxidans strain DY25 plasmid pDY25-E, complete sequence	58698-58726	6	0.793
NZ_CP040605_19	19.1\|5644760\|29\|NZ_CP040605\|CRISPRCasFinder	5644760-5644788	29	NZ_CP020471	Rhodobacter blasticus strain 28/5 plasmid pRsa, complete sequence	3368-3396	6	0.793
NZ_CP040605_7	7.2\|1511048\|33\|NZ_CP040605\|CRISPRCasFinder	1511048-1511080	33	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	738714-738746	7	0.788
NZ_CP040605_7	7.2\|1511048\|33\|NZ_CP040605\|CRISPRCasFinder	1511048-1511080	33	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1643674-1643706	7	0.788
NZ_CP040605_7	7.3\|1511106\|29\|NZ_CP040605\|CRISPRCasFinder	1511106-1511134	29	NC_015727	Cupriavidus necator N-1 plasmid pBB1, complete sequence	120181-120209	7	0.759
NZ_CP040605_7	7.5\|1510995\|30\|NZ_CP040605\|PILER-CR	1510995-1511024	30	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	529438-529467	7	0.767
NZ_CP040605_7	7.5\|1510995\|30\|NZ_CP040605\|PILER-CR	1510995-1511024	30	NZ_CP020613	Paracoccus contaminans strain RKI 16-01929T=LMG 29738T=CCM 8701T=CIP 111112T plasmid unnamed, complete sequence	55292-55321	7	0.767
NZ_CP040605_7	7.8\|1511159\|31\|NZ_CP040605\|PILER-CR	1511159-1511189	31	NZ_CP020539	Sphingobium herbicidovorans strain MH plasmid pMSHV, complete sequence	26490-26520	7	0.774
NZ_CP040605_18	18.1\|5642268\|29\|NZ_CP040605\|CRISPRCasFinder	5642268-5642296	29	NZ_CP024924	Sphingomonas sp. Cra20 plasmid unnamed, complete sequence	61531-61559	7	0.759
NZ_CP040605_19	19.1\|5644760\|29\|NZ_CP040605\|CRISPRCasFinder	5644760-5644788	29	NZ_CP024924	Sphingomonas sp. Cra20 plasmid unnamed, complete sequence	61531-61559	7	0.759
NZ_CP040605_7	7.2\|1511048\|33\|NZ_CP040605\|CRISPRCasFinder	1511048-1511080	33	NZ_CP053906	Hymenobacter sp. BRD67 plasmid unnamed2, complete sequence	86921-86953	8	0.758
NZ_CP040605_7	7.2\|1511048\|33\|NZ_CP040605\|CRISPRCasFinder	1511048-1511080	33	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	1213082-1213114	8	0.758
NZ_CP040605_7	7.8\|1511159\|31\|NZ_CP040605\|PILER-CR	1511159-1511189	31	NZ_CP023440	Thauera sp. K11 plasmid pTX1, complete sequence	106178-106208	8	0.742
NZ_CP040605_13	13.2\|3319243\|31\|NZ_CP040605\|CRISPRCasFinder	3319243-3319273	31	NC_009620	Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence	1331418-1331448	8	0.742
NZ_CP040605_18	18.1\|5642268\|29\|NZ_CP040605\|CRISPRCasFinder	5642268-5642296	29	NC_002679	Mesorhizobium japonicum MAFF 303099 plasmid pMLa, complete sequence	68287-68315	8	0.724
NZ_CP040605_19	19.1\|5644760\|29\|NZ_CP040605\|CRISPRCasFinder	5644760-5644788	29	NC_002679	Mesorhizobium japonicum MAFF 303099 plasmid pMLa, complete sequence	68287-68315	8	0.724
NZ_CP040605_20	20.1\|5647238\|34\|NZ_CP040605\|CRISPRCasFinder	5647238-5647271	34	NZ_CP021409	Celeribacter manganoxidans strain DY25 plasmid pDY25-E, complete sequence	58698-58731	8	0.765
NZ_CP040605_5	5.2\|1451417\|32\|NZ_CP040605\|CRISPRCasFinder	1451417-1451448	32	NC_016000	Sphingobium chungbukense strain DJ77 plasmid pSY2, complete sequence	8859-8890	9	0.719
NZ_CP040605_7	7.2\|1511048\|33\|NZ_CP040605\|CRISPRCasFinder	1511048-1511080	33	NZ_CP047175	Rathayibacter sp. VKM Ac-2760 plasmid unnamed2, complete sequence	62717-62749	9	0.727
NZ_CP040605_7	7.2\|1511048\|33\|NZ_CP040605\|CRISPRCasFinder	1511048-1511080	33	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	1222561-1222593	9	0.727
NZ_CP040605_7	7.2\|1511048\|33\|NZ_CP040605\|CRISPRCasFinder	1511048-1511080	33	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	864779-864811	9	0.727
NZ_CP040605_7	7.5\|1510995\|30\|NZ_CP040605\|PILER-CR	1510995-1511024	30	NZ_CP040763	Paracoccus sp. 2251 plasmid unnamed4, complete sequence	175514-175543	9	0.7
NZ_CP040605_7	7.7\|1511105\|32\|NZ_CP040605\|PILER-CR	1511105-1511136	32	NC_015727	Cupriavidus necator N-1 plasmid pBB1, complete sequence	120179-120210	9	0.719
NZ_CP040605_21	21.1\|5649719\|34\|NZ_CP040605\|CRISPRCasFinder	5649719-5649752	34	NZ_CP020471	Rhodobacter blasticus strain 28/5 plasmid pRsa, complete sequence	3368-3401	9	0.735
NZ_CP040605_24	24.1\|8037695\|33\|NZ_CP040605\|CRISPRCasFinder	8037695-8037727	33	NC_004934	Streptomyces violaceoruber strain SANK95570 plasmid pSV2, complete sequence	30873-30905	9	0.727
NZ_CP040605_20	20.1\|5647238\|34\|NZ_CP040605\|CRISPRCasFinder	5647238-5647271	34	NZ_CP020471	Rhodobacter blasticus strain 28/5 plasmid pRsa, complete sequence	3368-3401	10	0.706

1. spacer 4.1|583712|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP009649 (Bacillus pseudomycoides strain BTZ plasmid pBTZ_2, complete sequence) position: , mismatch: 2, identity: 0.913

aatttccattgaaatcgaaggtc	CRISPR spacer
aatttccactgaaatcgaaggtg	Protospacer
********.*************

2. spacer 22.2|5907345|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP020447 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed7, complete sequence) position: , mismatch: 2, identity: 0.913

aagccgaggaatacggagaggaa	CRISPR spacer
aagccgaggaataccgcgaggaa	Protospacer
************** * ******

3. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_MF133496 (Klebsiella pneumoniae strain 675920 plasmid p675920-2, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

4. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP033957 (Klebsiella pneumoniae strain L39_2 plasmid p4_L39, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

5. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP024461 (Klebsiella pneumoniae strain QS17-0161 plasmid pMR0617tem, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

6. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to AP022370 (Klebsiella pneumoniae E328 plasmid pE328_IMP6 DNA, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

7. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP028480 (Klebsiella pneumoniae strain 2e plasmid unnamed2) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

8. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP035208 (Klebsiella quasipneumoniae strain TH114 plasmid pTH114-3, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

9. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP035213 (Klebsiella pneumoniae strain TH164 plasmid pTH164-3, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

10. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP054747 (Klebsiella pneumoniae strain KP20194c4 plasmid pKP20194c4-p3, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

11. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP054723 (Klebsiella pneumoniae strain KP20194f plasmid pKP20194f-p3, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

12. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to CP050279 (Klebsiella pneumoniae strain 10553 plasmid unnamed4, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

13. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP023985 (Klebsiella variicola strain X39 plasmid pX39-8, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

14. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_MF190368 (Klebsiella pneumoniae strain 205880 plasmid p205880-qnrS, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

15. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_MG288684 (Klebsiella aerogenes strain E20 plasmid pE20-qnrS, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

16. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to MT035876 (Klebsiella pneumoniae strain KP18-3-8 plasmid pKP18-3-8-IncFII, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

17. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to MT090960 (Klebsiella pneumoniae strain KP18-2079 plasmid pKP18-2079_tetA, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

18. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP033775 (Klebsiella pneumoniae strain FDAARGOS_531 plasmid unnamed2, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

19. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP031261 (Klebsiella quasipneumoniae strain L22 plasmid pL22-4, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

20. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP041095 (Klebsiella pneumoniae subsp. pneumoniae strain KPCTRSRTH01 plasmid unnamed3, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

21. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP041376 (Klebsiella pneumoniae strain KP58 plasmid pKP58-3, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

22. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP032243 (Klebsiella pneumoniae strain XJ-K2 plasmid unnamed3, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

23. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP047195 (Klebsiella pneumoniae strain Kp36 plasmid unnamed3, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

24. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP029382 (Klebsiella pneumoniae subsp. pneumoniae strain SCKP020079 plasmid pQnrS1_020079, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

25. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP034126 (Klebsiella pneumoniae strain BJCFK909 plasmid p3s1, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

26. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP018341 (Klebsiella pneumoniae isolate Kp_Goe_154414 plasmid pKp_Goe_414-4, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

27. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to CP050283 (Klebsiella pneumoniae strain 9949 plasmid unnamed3, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

28. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP054765 (Klebsiella pneumoniae strain KP20194b2 plasmid pKP20194b2-p3, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

29. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP054735 (Klebsiella pneumoniae strain KP20194d plasmid pKP20194d-p3, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

30. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to CP050288 (Klebsiella pneumoniae strain 9630 plasmid unnamed3, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

31. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_MH341574 (Klebsiella pneumoniae strain MYKLB95 plasmid MYKLB95-1, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

32. spacer 6.2|1507013|23|NZ_CP040605|CRISPRCasFinder matches to NZ_CP035205 (Klebsiella pneumoniae strain LH94 plasmid pLH94-3, complete sequence) position: , mismatch: 3, identity: 0.87

ctccgggcactggccacgcctgg	CRISPR spacer
atccggtcactggccacgcctgc	Protospacer
 ***** ***************

33. spacer 5.3|1451473|27|NZ_CP040605|CRISPRCasFinder matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.815

cacaccggacgccgtcccgcgtttccg---	CRISPR spacer
cacaccggacgccgtcccg---gtgcgggt	Protospacer
*******************    * **

34. spacer 5.3|1451473|27|NZ_CP040605|CRISPRCasFinder matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.815

cacaccggacgccgtcccgcgtttccg	CRISPR spacer
cggtccggacgccgtaccgcgttcccg	Protospacer
*.  *********** *******.***

35. spacer 7.1|1510996|27|NZ_CP040605|CRISPRCasFinder matches to NZ_CP020613 (Paracoccus contaminans strain RKI 16-01929T=LMG 29738T=CCM 8701T=CIP 111112T plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

ccaccgcatctgccgggcccatgtgat	CRISPR spacer
cgaccgcatctgccgggccgatgaggg	Protospacer
* ***************** *** *.

36. spacer 7.4|1511160|28|NZ_CP040605|CRISPRCasFinder matches to NZ_CP020539 (Sphingobium herbicidovorans strain MH plasmid pMSHV, complete sequence) position: , mismatch: 5, identity: 0.821

ccgcagcccggcacaggcgttgctgggg	CRISPR spacer
acacagcctggaacaggcgttgctggga	Protospacer
 *.*****.** ***************.

37. spacer 10.1|1889857|27|NZ_CP040605|CRISPRCasFinder matches to NZ_AP019741 (Acinetobacter radioresistens DSM 6976 = NBRC 102413 = CIP 103788 strain NBRC 102413 plasmid pARA1, complete sequence) position: , mismatch: 5, identity: 0.815

cgggtactgctactgcggcgggtactg	CRISPR spacer
aagacattgctactgcggcgggtactg	Protospacer
 .*..*.********************

38. spacer 10.1|1889857|27|NZ_CP040605|CRISPRCasFinder matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

cgggtactgctactgcggcgggtactg	CRISPR spacer
cgggtactgctgctgcggctggttggg	Protospacer
***********.******* ***   *

39. spacer 7.1|1510996|27|NZ_CP040605|CRISPRCasFinder matches to NZ_CP040763 (Paracoccus sp. 2251 plasmid unnamed4, complete sequence) position: , mismatch: 6, identity: 0.778

ccaccgcatctgccgggcccatgtgat	CRISPR spacer
ctaccgcatctgccgggccgatgacca	Protospacer
*.***************** ***

40. spacer 7.1|1510996|27|NZ_CP040605|CRISPRCasFinder matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

ccaccgcatctgccgggcccatgtgat	CRISPR spacer
ccaccgcatcgtccgggcccatggctg	Protospacer
**********  ***********

41. spacer 7.4|1511160|28|NZ_CP040605|CRISPRCasFinder matches to NZ_CP023440 (Thauera sp. K11 plasmid pTX1, complete sequence) position: , mismatch: 6, identity: 0.786

ccgcagcccggcacaggcgttgctgggg	CRISPR spacer
gagcagcccggcaccggcgttgctcctg	Protospacer
  ************ *********   *

42. spacer 7.9|1510995|34|NZ_CP040605|CRT matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.824

tccaccgcatctgccgggcccatgtgatgtgagg-	CRISPR spacer
tccaccgcatcgtccgggcccatg-gctgggagac	Protospacer
***********  *********** * ** ***.

43. spacer 18.1|5642268|29|NZ_CP040605|CRISPRCasFinder matches to NZ_CP021409 (Celeribacter manganoxidans strain DY25 plasmid pDY25-E, complete sequence) position: , mismatch: 6, identity: 0.793

tccaccgtgatcgcggcaggcaggtggag	CRISPR spacer
agttcggtgatcgcggcaggcaggtggcg	Protospacer
  . * ********************* *

44. spacer 18.1|5642268|29|NZ_CP040605|CRISPRCasFinder matches to NZ_CP020471 (Rhodobacter blasticus strain 28/5 plasmid pRsa, complete sequence) position: , mismatch: 6, identity: 0.793

tccaccgtgatcgcggcaggcaggtggag	CRISPR spacer
gccaccgtgatcgcggcacggaggtttaa	Protospacer
 ***************** * ****  *.

45. spacer 19.1|5644760|29|NZ_CP040605|CRISPRCasFinder matches to NZ_CP021409 (Celeribacter manganoxidans strain DY25 plasmid pDY25-E, complete sequence) position: , mismatch: 6, identity: 0.793

tccaccgtgatcgcggcaggcaggtggag	CRISPR spacer
agttcggtgatcgcggcaggcaggtggcg	Protospacer
  . * ********************* *

46. spacer 19.1|5644760|29|NZ_CP040605|CRISPRCasFinder matches to NZ_CP020471 (Rhodobacter blasticus strain 28/5 plasmid pRsa, complete sequence) position: , mismatch: 6, identity: 0.793

tccaccgtgatcgcggcaggcaggtggag	CRISPR spacer
gccaccgtgatcgcggcacggaggtttaa	Protospacer
 ***************** * ****  *.

47. spacer 7.2|1511048|33|NZ_CP040605|CRISPRCasFinder matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 7, identity: 0.788

tccacgccccagcggctcggcgtggtgccggag	CRISPR spacer
gccctggcgcagcggctcggcgtggcgctggag	Protospacer
 ** .* * ****************.**.****

48. spacer 7.2|1511048|33|NZ_CP040605|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.788

tccacgccccagcggctcggcgtggtgccggag	CRISPR spacer
accatcctgcagcggctgggcgtggtgccgcag	Protospacer
 ***. *. ******** ************ **

49. spacer 7.3|1511106|29|NZ_CP040605|CRISPRCasFinder matches to NC_015727 (Cupriavidus necator N-1 plasmid pBB1, complete sequence) position: , mismatch: 7, identity: 0.759

cgacggggcgcgcgagcatgggtcctgac	CRISPR spacer
agacgcggcgcgcgagcattggtctggta	Protospacer
 **** ************* ****. *

50. spacer 7.5|1510995|30|NZ_CP040605|PILER-CR matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

tccaccgcatctgccgggcccatgtgatgt	CRISPR spacer
tccaccgcatcgtccgggcccatggctggg	Protospacer
***********  ***********    *

51. spacer 7.5|1510995|30|NZ_CP040605|PILER-CR matches to NZ_CP020613 (Paracoccus contaminans strain RKI 16-01929T=LMG 29738T=CCM 8701T=CIP 111112T plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

tccaccgcatctgccgggcccatgtgatgt	CRISPR spacer
ccgaccgcatctgccgggccgatgagggga	Protospacer
.* ***************** *** *. *

52. spacer 7.8|1511159|31|NZ_CP040605|PILER-CR matches to NZ_CP020539 (Sphingobium herbicidovorans strain MH plasmid pMSHV, complete sequence) position: , mismatch: 7, identity: 0.774

tccgcagcccggcacaggcgttgctggggtg	CRISPR spacer
aacacagcctggaacaggcgttgctgggatc	Protospacer
  *.*****.** ***************.*

53. spacer 18.1|5642268|29|NZ_CP040605|CRISPRCasFinder matches to NZ_CP024924 (Sphingomonas sp. Cra20 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

tccaccgtgatcgcggcaggcaggtggag	CRISPR spacer
cccaccatgatcgcgacaggcaggattac	Protospacer
.*****.********.********   *

54. spacer 19.1|5644760|29|NZ_CP040605|CRISPRCasFinder matches to NZ_CP024924 (Sphingomonas sp. Cra20 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

tccaccgtgatcgcggcaggcaggtggag	CRISPR spacer
cccaccatgatcgcgacaggcaggattac	Protospacer
.*****.********.********   *

55. spacer 7.2|1511048|33|NZ_CP040605|CRISPRCasFinder matches to NZ_CP053906 (Hymenobacter sp. BRD67 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.758

tccacgccccagcggctcggcgtggtgccggag	CRISPR spacer
cgcttacaccagcagctaggcgtggtgccggag	Protospacer
. * ..* *****.*** ***************

56. spacer 7.2|1511048|33|NZ_CP040605|CRISPRCasFinder matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 8, identity: 0.758

tccacgccccagcggctcggcgtggtgccggag	CRISPR spacer
ctgccgagccaacgtctcggcgtggtgccggag	Protospacer
..  **  ***.** ******************

57. spacer 7.8|1511159|31|NZ_CP040605|PILER-CR matches to NZ_CP023440 (Thauera sp. K11 plasmid pTX1, complete sequence) position: , mismatch: 8, identity: 0.742

tccgcagcccggcacaggcgttgctggggtg	CRISPR spacer
cgagcagcccggcaccggcgttgctcctggg	Protospacer
.  ************ *********   * *

58. spacer 13.2|3319243|31|NZ_CP040605|CRISPRCasFinder matches to NC_009620 (Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence) position: , mismatch: 8, identity: 0.742

aagccaaccaggtccaccgccgatttcggat	CRISPR spacer
gcagccgccaggtccagcgccgatgtcggat	Protospacer
. . * .********* ******* ******

59. spacer 18.1|5642268|29|NZ_CP040605|CRISPRCasFinder matches to NC_002679 (Mesorhizobium japonicum MAFF 303099 plasmid pMLa, complete sequence) position: , mismatch: 8, identity: 0.724

tccaccgtgatcgcggcaggcaggtggag	CRISPR spacer
ggttctctgatcgcggctggcaggtggaa	Protospacer
  . *. ********** **********.

60. spacer 19.1|5644760|29|NZ_CP040605|CRISPRCasFinder matches to NC_002679 (Mesorhizobium japonicum MAFF 303099 plasmid pMLa, complete sequence) position: , mismatch: 8, identity: 0.724

tccaccgtgatcgcggcaggcaggtggag	CRISPR spacer
ggttctctgatcgcggctggcaggtggaa	Protospacer
  . *. ********** **********.

61. spacer 20.1|5647238|34|NZ_CP040605|CRISPRCasFinder matches to NZ_CP021409 (Celeribacter manganoxidans strain DY25 plasmid pDY25-E, complete sequence) position: , mismatch: 8, identity: 0.765

tccaccgtgatcgcggcaggcaggtggaggtgcg	CRISPR spacer
agttcggtgatcgcggcaggcaggtggcgctggg	Protospacer
  . * ********************* * ** *

62. spacer 5.2|1451417|32|NZ_CP040605|CRISPRCasFinder matches to NC_016000 (Sphingobium chungbukense strain DJ77 plasmid pSY2, complete sequence) position: , mismatch: 9, identity: 0.719

taacgcctgccagcacgcctttcgtgccgttg	CRISPR spacer
taacgcccgccagcacgccttgcgctagatca	Protospacer
*******.************* **.   .*..

63. spacer 7.2|1511048|33|NZ_CP040605|CRISPRCasFinder matches to NZ_CP047175 (Rathayibacter sp. VKM Ac-2760 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.727

tccacgccccagcggctcggcgtggtgccggag	CRISPR spacer
gtgtcgcgccagcggctcggcgtcgtgcctgcc	Protospacer
 .  *** *************** ***** *

64. spacer 7.2|1511048|33|NZ_CP040605|CRISPRCasFinder matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 9, identity: 0.727

tccacgccccagcggctcggcgtggtgccggag	CRISPR spacer
ctgccgagccaacgtctcggcgtggtgccggaa	Protospacer
..  **  ***.** *****************.

65. spacer 7.2|1511048|33|NZ_CP040605|CRISPRCasFinder matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 9, identity: 0.727

tccacgccccagcggctcggcgtggtgccggag	CRISPR spacer
ctgccgagccaacgtctcggcgtggtgccggaa	Protospacer
..  **  ***.** *****************.

66. spacer 7.5|1510995|30|NZ_CP040605|PILER-CR matches to NZ_CP040763 (Paracoccus sp. 2251 plasmid unnamed4, complete sequence) position: , mismatch: 9, identity: 0.7

tccaccgcatctgccgggcccatgtgatgt	CRISPR spacer
actaccgcatctgccgggccgatgaccaag	Protospacer
 *.***************** ***    .

67. spacer 7.7|1511105|32|NZ_CP040605|PILER-CR matches to NC_015727 (Cupriavidus necator N-1 plasmid pBB1, complete sequence) position: , mismatch: 9, identity: 0.719

ccgacggggcgcgcgagcatgggtcctgacgt	CRISPR spacer
cagacgcggcgcgcgagcattggtctggtacc	Protospacer
* **** ************* ****. *   .

68. spacer 21.1|5649719|34|NZ_CP040605|CRISPRCasFinder matches to NZ_CP020471 (Rhodobacter blasticus strain 28/5 plasmid pRsa, complete sequence) position: , mismatch: 9, identity: 0.735

tccaccgtgatcgcggcaggcaggtggaggcgcg	CRISPR spacer
gccaccgtgatcgcggcacggaggtttaagccat	Protospacer
 ***************** * ****  *.**

69. spacer 24.1|8037695|33|NZ_CP040605|CRISPRCasFinder matches to NC_004934 (Streptomyces violaceoruber strain SANK95570 plasmid pSV2, complete sequence) position: , mismatch: 9, identity: 0.727

gtgcgggtagcggtgtgcccggccggtccgggt	CRISPR spacer
cggcgcgtagcggtgtgcccgcccggcggtggc	Protospacer
  *** *************** ****.   **.

70. spacer 20.1|5647238|34|NZ_CP040605|CRISPRCasFinder matches to NZ_CP020471 (Rhodobacter blasticus strain 28/5 plasmid pRsa, complete sequence) position: , mismatch: 10, identity: 0.706

tccaccgtgatcgcggcaggcaggtggaggtgcg	CRISPR spacer
gccaccgtgatcgcggcacggaggtttaagccat	Protospacer
 ***************** * ****  *.*.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

778831 : 825223

Mycobacterium_phage(20.0%)

transposase,integrase,holin

attL 811440:811459|attR 831279:831298

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168584662.1\|778831_779221_-\|holin	phage holin family protein	NA	NA	NA	NA
WP_168584663.1\|779336_780302_-	exopolyphosphatase	NA	NA	NA	NA
WP_168584664.1\|780553_781600_+	LLM class F420-dependent oxidoreductase	NA	NA	NA	NA
WP_168584665.1\|781818_782598_+	DUF952 domain-containing protein	A0A291AU44	Pandoravirus	2.1e-11	37.7
WP_168584666.1\|782545_782956_-	hypothetical protein	NA	NA	NA	NA
WP_168584667.1\|783360_783768_+	hypothetical protein	NA	NA	NA	NA
WP_168584668.1\|784202_785702_+	amino acid permease	NA	NA	NA	NA
WP_168584669.1\|785972_786242_-	UBP-type zinc finger domain-containing protein	NA	NA	NA	NA
WP_168584670.1\|786346_787912_+	Na+/H+ antiporter	A0A2H4J178	uncultured_Caudovirales_phage	4.6e-10	28.8
WP_168584671.1\|788003_788747_-	IclR family transcriptional regulator	NA	NA	NA	NA
WP_168584672.1\|788966_790154_+	oxidoreductase	NA	NA	NA	NA
WP_168584673.1\|790164_790992_-	alpha/beta hydrolase	A0A249XMC3	Mycobacterium_phage	1.9e-18	30.0
WP_168584674.1\|791161_791812_-	sarcosine oxidase subunit gamma	NA	NA	NA	NA
WP_168584675.1\|791777_794612_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_168584676.1\|794608_794875_-	sarcosine oxidase subunit delta	NA	NA	NA	NA
WP_168584677.1\|795108_796332_-	sarcosine oxidase subunit beta family protein	NA	NA	NA	NA
WP_168584678.1\|796418_797075_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_168584679.1\|797299_799771_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_168584680.1\|799987_801184_+	glycine cleavage system protein T	NA	NA	NA	NA
WP_168589772.1\|801220_802063_+	5,10-methylenetetrahydrofolate reductase	NA	NA	NA	NA
WP_168584681.1\|802059_803757_+	formate--tetrahydrofolate ligase	NA	NA	NA	NA
WP_168584682.1\|803806_803968_-	DUF397 domain-containing protein	NA	NA	NA	NA
WP_168584683.1\|804133_804751_-	helix-turn-helix domain-containing protein	A0A1J0MCL6	Streptomyces_phage	9.3e-23	36.8
WP_168584684.1\|804806_805151_+	hypothetical protein	NA	NA	NA	NA
WP_168584685.1\|805382_805913_+	hypothetical protein	NA	NA	NA	NA
WP_168584686.1\|806025_806361_+	YnfA family protein	NA	NA	NA	NA
WP_168584687.1\|806370_806715_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_168584688.1\|806814_808713_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	3.2e-98	36.8
WP_168584689.1\|808916_809768_+	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_168589773.1\|809998_810589_-	DUF1349 domain-containing protein	NA	NA	NA	NA
WP_168584690.1\|811173_813702_-	DUF3516 domain-containing protein	M1HP49	Acanthocystis_turfacea_Chlorella_virus	6.1e-44	32.8
811440:811459	attL	NA	NA	NA	NA
WP_168584691.1\|813859_814060_+	hypothetical protein	NA	NA	NA	NA
WP_168584692.1\|814106_814388_+	type II toxin-antitoxin system prevent-host-death family antitoxin	NA	NA	NA	NA
WP_168584693.1\|814384_814645_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A2P1N333	Gordonia_phage	1.5e-14	46.3
WP_168584694.1\|816783_819003_+	methylmalonyl-CoA mutase	NA	NA	NA	NA
WP_168584695.1\|819005_819992_+	methylmalonyl Co-A mutase-associated GTPase MeaB	NA	NA	NA	NA
WP_168584696.1\|820016_820373_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_168584697.1\|820628_820826_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	6.0e-08	45.0
WP_168584698.1\|820889_821189_-	hypothetical protein	NA	NA	NA	NA
WP_168584699.1\|821185_823105_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_168584700.1\|823064_824156_-\|integrase	tyrosine-type recombinase/integrase	A0A2L1ISS9	Mycobacterium_phage	1.4e-10	29.6
WP_168589774.1\|824240_824960_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_168584701.1\|824935_825223_-\|transposase	transposase	Q6H9S4	Enterobacteria_phage	3.1e-13	44.4
831279:831298	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1409350 : 1475257

Trichoplusia_ni_ascovirus(25.0%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168589851.1\|1409350_1411012_-\|tRNA	arginine--tRNA ligase	NA	NA	NA	NA
WP_168585139.1\|1411224_1412010_+	DUF3105 domain-containing protein	NA	NA	NA	NA
WP_168585140.1\|1412013_1412685_+	DUF305 domain-containing protein	NA	NA	NA	NA
WP_168585141.1\|1412724_1413642_-	cation transporter	NA	NA	NA	NA
WP_168585142.1\|1414424_1415147_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	1.2e-08	28.3
WP_168585143.1\|1415201_1415759_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_168585144.1\|1415991_1416744_-	FadR family transcriptional regulator	NA	NA	NA	NA
WP_168585145.1\|1418433_1418985_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_168585146.1\|1421562_1421901_+	hypothetical protein	NA	NA	NA	NA
WP_168585147.1\|1422143_1425098_+	ATP-binding protein	NA	NA	NA	NA
WP_168585148.1\|1425149_1425590_+	roadblock/LC7 domain-containing protein	NA	NA	NA	NA
WP_168585149.1\|1425597_1426197_+	DUF742 domain-containing protein	NA	NA	NA	NA
WP_168585150.1\|1426274_1426880_+	ATP-binding protein	NA	NA	NA	NA
WP_168585151.1\|1426936_1427584_-	PDZ domain-containing protein	A0A1B1IT49	uncultured_Mediterranean_phage	4.7e-09	28.6
WP_168585152.1\|1427690_1429052_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_168585153.1\|1429074_1429569_-\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_168585154.1\|1429850_1430891_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_168585154.1\|1431439_1432480_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_168585155.1\|1432571_1432961_+	hypothetical protein	NA	NA	NA	NA
WP_168585156.1\|1436425_1436653_+	DUF3311 domain-containing protein	NA	NA	NA	NA
WP_168585157.1\|1436649_1438128_+	sodium:solute symporter family protein	NA	NA	NA	NA
WP_168585158.1\|1438192_1439137_-	patatin-like phospholipase family protein	NA	NA	NA	NA
WP_168589852.1\|1439199_1439634_-\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_168585159.1\|1439803_1441162_-	beta-lactamase family protein	A0A2P1CHE9	Mycobacterium_phage	1.1e-15	27.2
WP_168585160.1\|1441278_1442235_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_168589853.1\|1442580_1444671_-	penicillin-binding protein	NA	NA	NA	NA
WP_168585161.1\|1444962_1445343_+	hypothetical protein	NA	NA	NA	NA
WP_168585162.1\|1445335_1445755_-	hypothetical protein	NA	NA	NA	NA
WP_168589854.1\|1446093_1447236_-	MFS transporter	NA	NA	NA	NA
WP_168585163.1\|1449209_1449941_-	cell wall anchor protein	NA	NA	NA	NA
WP_168585164.1\|1451756_1452590_+	hypothetical protein	NA	NA	NA	NA
WP_168585165.1\|1452824_1453103_+	hypothetical protein	NA	NA	NA	NA
WP_168585166.1\|1453585_1455802_-	3-hydroxyacyl-CoA dehydrogenase	NA	NA	NA	NA
WP_168585167.1\|1455816_1457031_-	acetyl-CoA C-acetyltransferase	NA	NA	NA	NA
WP_168585168.1\|1457122_1458445_-	4Fe-4S dicluster domain-containing protein	NA	NA	NA	NA
WP_168589855.1\|1458444_1459662_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_168585169.1\|1459700_1461185_-	FAD-binding protein	NA	NA	NA	NA
WP_168585170.1\|1461633_1461960_+	hypothetical protein	NA	NA	NA	NA
WP_168585171.1\|1461956_1463126_+	hypothetical protein	NA	NA	NA	NA
WP_168585172.1\|1463148_1463913_+	hypothetical protein	NA	NA	NA	NA
WP_168585173.1\|1463936_1464452_+	hypothetical protein	NA	NA	NA	NA
WP_168585174.1\|1464762_1465155_-	hypothetical protein	NA	NA	NA	NA
WP_168585175.1\|1465138_1465624_-	hypothetical protein	NA	NA	NA	NA
WP_168585176.1\|1465630_1466794_-	alkaline phosphatase family protein	NA	NA	NA	NA
WP_168585177.1\|1466836_1468015_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_168585178.1\|1468235_1469369_-	CoA transferase	NA	NA	NA	NA
WP_168585179.1\|1470488_1471205_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_168585180.1\|1471322_1472645_+	AMP-binding protein	A0A1V0SBX8	Catovirus	3.1e-31	24.0
WP_168585181.1\|1473245_1474562_-	MHS family MFS transporter	NA	NA	NA	NA
WP_168585182.1\|1474759_1475257_+\|protease	protease inhibitor	NA	NA	NA	NA

DBSCAN-SWA_3

3333884 : 3376153

Mycobacterium_phage(22.22%)

transposase,integrase

attL 3336309:3336324|attR 3375757:3375772

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168586541.1\|3333884_3334286_+\|transposase	IS200/IS605 family transposase	I4AZI8	Saccharomonospora_phage	4.2e-32	50.4
WP_168586542.1\|3334282_3335290_+\|transposase	transposase	A0A068A1P5	Thermus_phage	5.9e-43	38.6
WP_168586543.1\|3335671_3335959_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_168586544.1\|3336257_3336497_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
3336309:3336324	attL	NA	NA	NA	NA
WP_168586545.1\|3336514_3337351_-	ABC transporter permease	NA	NA	NA	NA
WP_168586546.1\|3337347_3338322_-	ABC transporter ATP-binding protein	A0A2R8FFL6	Cedratvirus	8.6e-15	30.5
WP_168586547.1\|3338910_3339411_+	hypothetical protein	NA	NA	NA	NA
WP_168586548.1\|3339731_3341201_-	peptidase S10	NA	NA	NA	NA
WP_168590093.1\|3341325_3342045_+	uracil-DNA glycosylase	NA	NA	NA	NA
WP_168590094.1\|3342063_3342261_+	ribbon-helix-helix protein, CopG family	NA	NA	NA	NA
WP_168586549.1\|3342257_3342635_+	type II toxin-antitoxin system death-on-curing family toxin	A0A1B3AYM0	Gordonia_phage	3.0e-16	52.5
WP_168586550.1\|3343366_3343957_-	hypothetical protein	NA	NA	NA	NA
WP_168586551.1\|3344206_3344392_-	hypothetical protein	NA	NA	NA	NA
WP_168586552.1\|3344388_3344700_-	hypothetical protein	NA	NA	NA	NA
WP_168586553.1\|3344717_3345404_-	hypothetical protein	NA	NA	NA	NA
WP_168586554.1\|3345498_3346473_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_168586555.1\|3346605_3346941_-	hypothetical protein	NA	NA	NA	NA
WP_168586556.1\|3347218_3347551_-	hypothetical protein	NA	NA	NA	NA
WP_168586557.1\|3347811_3348366_-	hypothetical protein	NA	NA	NA	NA
WP_168586558.1\|3348530_3348878_+	hypothetical protein	NA	NA	NA	NA
WP_168586559.1\|3349042_3349552_-	hypothetical protein	G3MA75	Bacillus_virus	2.2e-17	37.7
WP_168586560.1\|3349548_3350001_-	HIT domain-containing protein	S5VWB9	Mycobacterium_phage	9.2e-20	51.8
WP_168586561.1\|3350215_3350632_-	hypothetical protein	NA	NA	NA	NA
WP_168586562.1\|3350628_3350844_-	hypothetical protein	NA	NA	NA	NA
WP_168584100.1\|3351311_3351734_-	hypothetical protein	NA	NA	NA	NA
WP_168586563.1\|3352151_3353474_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_168590095.1\|3353870_3354926_+	hypothetical protein	NA	NA	NA	NA
WP_168590096.1\|3355384_3355978_-	hypothetical protein	NA	NA	NA	NA
WP_168586564.1\|3356292_3357105_+	ESX secretion-associated protein EspG	NA	NA	NA	NA
WP_168590097.1\|3357238_3357592_+	PE domain-containing protein	NA	NA	NA	NA
WP_168586565.1\|3357588_3358161_+	DUF3558 domain-containing protein	NA	NA	NA	NA
WP_168586566.1\|3358173_3359400_+	PPE domain-containing protein	NA	NA	NA	NA
WP_168586567.1\|3359441_3359750_+	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
WP_168586568.1\|3359752_3360046_+	hypothetical protein	NA	NA	NA	NA
WP_168586569.1\|3360049_3360358_+	hypothetical protein	NA	NA	NA	NA
WP_168586570.1\|3360379_3361045_+	hypothetical protein	NA	NA	NA	NA
WP_168586571.1\|3361041_3361641_+	hypothetical protein	NA	NA	NA	NA
WP_168586572.1\|3361672_3361906_-	hypothetical protein	NA	NA	NA	NA
WP_168586573.1\|3362034_3362265_-	hypothetical protein	NA	NA	NA	NA
WP_168586574.1\|3362264_3362507_-	hypothetical protein	NA	NA	NA	NA
WP_168586575.1\|3362859_3363714_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_168586576.1\|3363737_3363935_+	DUF397 domain-containing protein	NA	NA	NA	NA
WP_168586577.1\|3364151_3368921_+	DEAD/DEAH box helicase	A0A2H4UVA3	Bodo_saltans_virus	8.2e-34	24.1
WP_168586578.1\|3369466_3369979_+	hypothetical protein	NA	NA	NA	NA
WP_168586579.1\|3369975_3371259_-\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	3.9e-180	73.9
WP_168590098.1\|3372003_3373683_+	maturase	A0A0U4J920	Pseudomonas_phage	1.1e-20	27.2
WP_168586580.1\|3374509_3376153_+\|transposase	ISAzo13 family transposase	NA	NA	NA	NA
3375757:3375772	attR	NA	NA	NA	NA

DBSCAN-SWA_4

3912832 : 3977814

Saccharomonospora_phage(21.43%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168586968.1\|3912832_3913459_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	5.0e-40	50.6
WP_168586969.1\|3913497_3914130_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A248SJ97	Salicola_phage	2.1e-30	38.9
WP_168586970.1\|3914340_3914517_-	hypothetical protein	NA	NA	NA	NA
WP_168586971.1\|3914618_3915899_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	7.9e-141	59.4
WP_168586972.1\|3916157_3916796_+	serine hydrolase family protein	NA	NA	NA	NA
WP_168586973.1\|3916801_3917677_-	esterase family protein	NA	NA	NA	NA
WP_168586974.1\|3917750_3918587_-	formate dehydrogenase accessory sulfurtransferase FdhD	NA	NA	NA	NA
WP_168586975.1\|3918692_3920030_+	OFA family MFS transporter	NA	NA	NA	NA
WP_168586976.1\|3920575_3921184_+	DUF1963 domain-containing protein	NA	NA	NA	NA
WP_168586977.1\|3921415_3923713_-	FdhF/YdeP family oxidoreductase	NA	NA	NA	NA
WP_168586978.1\|3923840_3926546_+\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	5.2e-142	38.8
WP_168586979.1\|3926886_3928254_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_168590170.1\|3928316_3928733_+	DUF4233 domain-containing protein	NA	NA	NA	NA
WP_168586980.1\|3928793_3929648_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_168586981.1\|3929759_3930665_+	DMT family transporter	NA	NA	NA	NA
WP_168586982.1\|3930688_3931789_-	zinc-binding dehydrogenase	NA	NA	NA	NA
WP_168586983.1\|3931972_3933511_+	alkaline phosphatase	NA	NA	NA	NA
WP_168586984.1\|3933571_3933802_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_168590171.1\|3933851_3934220_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_168586985.1\|3934325_3934736_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	6.8e-30	50.0
WP_168586986.1\|3934988_3936953_+	TIGR03960 family B12-binding radical SAM protein	NA	NA	NA	NA
WP_168586987.1\|3937243_3938038_+	DUF2344 domain-containing protein	NA	NA	NA	NA
WP_168586988.1\|3938205_3941055_+	Rne/Rng family ribonuclease	NA	NA	NA	NA
WP_168586989.1\|3941119_3942028_+	hypothetical protein	NA	NA	NA	NA
WP_168586990.1\|3942079_3942688_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_168586991.1\|3944502_3945249_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_168585152.1\|3945669_3947031_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_168586992.1\|3947571_3947784_-	hypothetical protein	NA	NA	NA	NA
WP_168590172.1\|3947783_3947990_-	hypothetical protein	A0A2P1JSH5	Gordonia_phage	1.6e-08	50.0
WP_168586993.1\|3948021_3948165_-	hypothetical protein	NA	NA	NA	NA
WP_168586994.1\|3948456_3948906_-	hypothetical protein	NA	NA	NA	NA
WP_168590173.1\|3949418_3952616_-	arabinosyltransferase	NA	NA	NA	NA
WP_168586995.1\|3952791_3953778_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_168586996.1\|3953774_3955475_-	hypothetical protein	NA	NA	NA	NA
WP_010695780.1\|3955894_3956203_+	50S ribosomal protein L21	NA	NA	NA	NA
WP_010695777.1\|3956217_3956475_+	50S ribosomal protein L27	NA	NA	NA	NA
WP_168590174.1\|3956689_3958180_+	GTPase ObgE	NA	NA	NA	NA
WP_168586997.1\|3958176_3959298_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	3.5e-52	39.4
WP_168586998.1\|3959443_3960718_-	MFS transporter	Q6JIH2	Burkholderia_virus	6.6e-47	31.9
WP_168586999.1\|3960838_3961078_-	hypothetical protein	NA	NA	NA	NA
WP_168587000.1\|3961303_3961801_+	helix-turn-helix domain-containing protein	I4AZQ1	Saccharomonospora_phage	4.7e-17	42.1
WP_168587001.1\|3962449_3964570_-	ATP-dependent DNA helicase RecQ	Q9DSV4	Diadromus_pulchellus_ascovirus	9.0e-41	33.0
WP_168587002.1\|3964690_3966010_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.1e-102	51.9
WP_168587003.1\|3966398_3966620_+	ferredoxin	NA	NA	NA	NA
WP_168587004.1\|3966955_3967576_+	nicotinate-nucleotide adenylyltransferase	NA	NA	NA	NA
WP_168587005.1\|3967918_3968317_+	ribosome silencing factor	NA	NA	NA	NA
WP_168587006.1\|3968313_3968934_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_168587007.1\|3968968_3969829_+	DegV family protein	NA	NA	NA	NA
WP_168590175.1\|3970156_3970738_+	ComEA family DNA-binding protein	NA	NA	NA	NA
WP_168590176.1\|3970758_3973086_+	DUF4131 domain-containing protein	Q0H255	Geobacillus_phage	7.8e-22	29.6
WP_168590177.1\|3973606_3973813_-	DUF397 domain-containing protein	NA	NA	NA	NA
WP_168587008.1\|3973889_3974279_-	hypothetical protein	NA	NA	NA	NA
WP_168587009.1\|3974367_3975111_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_168587010.1\|3975710_3976046_+	hypothetical protein	NA	NA	NA	NA
WP_168587011.1\|3976193_3976592_+\|transposase	IS200/IS605 family transposase	I4AZI8	Saccharomonospora_phage	3.1e-64	89.2
WP_168584596.1\|3976596_3977814_+\|transposase	transposase	I4AZI9	Saccharomonospora_phage	1.3e-196	84.9

DBSCAN-SWA_5

3982351 : 4001941

Saccharomonospora_phage(60.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168587011.1\|3982351_3982750_+\|transposase	IS200/IS605 family transposase	I4AZI8	Saccharomonospora_phage	3.1e-64	89.2
WP_168584596.1\|3982754_3983972_+\|transposase	transposase	I4AZI9	Saccharomonospora_phage	1.3e-196	84.9
WP_168587015.1\|3983952_3984630_+	TSUP family transporter	NA	NA	NA	NA
WP_168587016.1\|3984819_3985149_+	hypothetical protein	NA	NA	NA	NA
WP_168584373.1\|3985165_3986056_-\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_168587017.1\|3987571_3987958_+	VOC family protein	NA	NA	NA	NA
WP_168587018.1\|3987995_3988277_-	DUF397 domain-containing protein	NA	NA	NA	NA
WP_168587019.1\|3988415_3989000_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_168587020.1\|3989130_3990981_+	elongation factor 4	A0A2K9L6L3	Tupanvirus	1.8e-21	39.8
WP_168587021.1\|3991116_3991362_+	hypothetical protein	NA	NA	NA	NA
WP_168587022.1\|3992303_3993128_-	NAD(P)H-binding protein	NA	NA	NA	NA
WP_168590178.1\|3993257_3993626_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_168587023.1\|3993552_3993864_-	hypothetical protein	NA	NA	NA	NA
WP_168584106.1\|3993876_3994296_-	hypothetical protein	NA	NA	NA	NA
WP_168590080.1\|3994839_3996336_+\|transposase	IS1380 family transposase	A0A222ZN33	Mycobacterium_phage	5.9e-71	38.9
WP_168587024.1\|3996479_3996731_-	hypothetical protein	NA	NA	NA	NA
WP_168584374.1\|3996787_3997552_-\|transposase	transposase	NA	NA	NA	NA
WP_168590179.1\|3998834_3999665_+	helix-turn-helix transcriptional regulator	I4AZQ1	Saccharomonospora_phage	6.8e-45	40.2
WP_168587025.1\|3999633_3999810_+	DUF397 domain-containing protein	NA	NA	NA	NA
WP_168587026.1\|4000067_4000229_-	hypothetical protein	NA	NA	NA	NA
WP_168587027.1\|4000264_4000597_-	hypothetical protein	NA	NA	NA	NA
WP_168587028.1\|4001032_4001941_+\|transposase	ISL3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_6

4818181 : 4888308

Mycobacterium_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168585154.1\|4818181_4819222_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_168587607.1\|4819345_4819762_+	WhiB family transcriptional regulator	NA	NA	NA	NA
WP_168587608.1\|4820048_4820528_-	hypothetical protein	NA	NA	NA	NA
WP_168584118.1\|4821035_4821392_-	hypothetical protein	NA	NA	NA	NA
WP_168587609.1\|4821538_4821847_-	hypothetical protein	NA	NA	NA	NA
WP_168590289.1\|4822344_4822560_+	hypothetical protein	NA	NA	NA	NA
WP_168587610.1\|4823281_4824310_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_168587611.1\|4824394_4824736_-	hypothetical protein	NA	NA	NA	NA
WP_168587612.1\|4824868_4825453_-	adenylate cyclase	NA	NA	NA	NA
WP_168587613.1\|4825647_4825908_-	hypothetical protein	NA	NA	NA	NA
WP_168587614.1\|4826071_4826440_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_168587615.1\|4826666_4826984_-	hypothetical protein	NA	NA	NA	NA
WP_168587616.1\|4827752_4828070_-	hypothetical protein	NA	NA	NA	NA
WP_168587617.1\|4828066_4828600_-	hypothetical protein	NA	NA	NA	NA
WP_168587618.1\|4829000_4830167_+	XRE family transcriptional regulator	NA	NA	NA	NA
WP_168587619.1\|4830171_4831068_+	aminoglycoside phosphotransferase family protein	NA	NA	NA	NA
WP_168587620.1\|4831269_4831950_+	hypothetical protein	NA	NA	NA	NA
WP_168587621.1\|4831946_4832507_+	hypothetical protein	NA	NA	NA	NA
WP_168587622.1\|4832503_4832974_+	hypothetical protein	NA	NA	NA	NA
WP_168587623.1\|4832970_4833222_+	hypothetical protein	NA	NA	NA	NA
WP_168584119.1\|4833807_4834047_-	hypothetical protein	NA	NA	NA	NA
WP_168587624.1\|4834839_4835277_-	HAD family hydrolase	NA	NA	NA	NA
WP_168590290.1\|4835591_4836476_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_168587625.1\|4836475_4836694_+	DUF397 domain-containing protein	NA	NA	NA	NA
WP_168587626.1\|4836738_4837731_+	aminoglycoside phosphotransferase family protein	NA	NA	NA	NA
WP_168587627.1\|4837740_4838730_-	hypothetical protein	NA	NA	NA	NA
WP_168587628.1\|4838737_4840012_-	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_168587629.1\|4840008_4841157_-	glycine amidinotransferase	NA	NA	NA	NA
WP_168587630.1\|4841207_4842194_-	aspartyl/asparaginyl beta-hydroxylase domain-containing protein	NA	NA	NA	NA
WP_168587631.1\|4842247_4843630_-	hypothetical protein	NA	NA	NA	NA
WP_168587632.1\|4843693_4844731_-	cytochrome P450	NA	NA	NA	NA
WP_168587633.1\|4846203_4848984_-	RNAseH domain-containing protein	NA	NA	NA	NA
WP_168587634.1\|4849012_4852444_-	signal recognition particle	NA	NA	NA	NA
WP_168587635.1\|4852436_4853630_-	hypothetical protein	NA	NA	NA	NA
WP_168587636.1\|4853571_4855230_-	PD-(D/E)XK nuclease family protein	NA	NA	NA	NA
WP_168587637.1\|4855448_4855826_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_168587638.1\|4856016_4859091_+	hypothetical protein	NA	NA	NA	NA
WP_168587639.1\|4859087_4859576_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_168587640.1\|4859833_4862755_-	AAA family ATPase	NA	NA	NA	NA
WP_168587641.1\|4862751_4863897_-	exonuclease SbcCD subunit D	NA	NA	NA	NA
WP_168587642.1\|4863887_4865183_-	DUF2399 domain-containing protein	NA	NA	NA	NA
WP_168587643.1\|4865179_4868029_-	hypothetical protein	NA	NA	NA	NA
WP_168587644.1\|4868298_4868961_-	hypothetical protein	NA	NA	NA	NA
WP_168587645.1\|4868957_4869497_-	hypothetical protein	NA	NA	NA	NA
WP_168587646.1\|4869489_4870725_-	hypothetical protein	NA	NA	NA	NA
WP_168590080.1\|4871174_4872671_+\|transposase	IS1380 family transposase	A0A222ZN33	Mycobacterium_phage	5.9e-71	38.9
WP_168587647.1\|4873912_4876366_-	hypothetical protein	NA	NA	NA	NA
WP_168590291.1\|4876709_4876937_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_168590292.1\|4878215_4879154_-	cyclase family protein	NA	NA	NA	NA
WP_168587648.1\|4879385_4879559_-	hypothetical protein	NA	NA	NA	NA
WP_168587649.1\|4880935_4881259_+	hypothetical protein	NA	NA	NA	NA
WP_168590293.1\|4882233_4882698_-	hypothetical protein	NA	NA	NA	NA
WP_168587650.1\|4883368_4884370_-\|transposase	transposase	NA	NA	NA	NA
WP_168587651.1\|4884544_4884862_+	hypothetical protein	NA	NA	NA	NA
WP_168590294.1\|4885182_4885500_+\|transposase	transposase family protein	NA	NA	NA	NA
WP_168587652.1\|4885656_4885983_+	hypothetical protein	NA	NA	NA	NA
WP_168587653.1\|4886072_4887599_+\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_168587654.1\|4888011_4888308_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_7

4912950 : 5038178

Staphylococcus_phage(50.0%)

transposase,integrase

attL 4903982:4903999|attR 5021742:5021758

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4903982:4903999	attL	NA	NA	NA	NA
WP_168587669.1\|4912950_4913181_+\|transposase	transposase	NA	NA	NA	NA
4903982:4903999	attL	NA	NA	NA	NA
WP_168587670.1\|4913183_4914191_+\|transposase	transposase	NA	NA	NA	NA
WP_168587671.1\|4914268_4915771_-	formate hydrogenase	NA	NA	NA	NA
WP_168587672.1\|4915770_4917249_-	hydrogenase	NA	NA	NA	NA
WP_168587673.1\|4917248_4917911_-	hypothetical protein	NA	NA	NA	NA
WP_168587674.1\|4917926_4918874_-	formate hydrogenlyase	NA	NA	NA	NA
WP_168587675.1\|4918870_4920886_-	hydrogenase 4 subunit B	NA	NA	NA	NA
WP_168590298.1\|4920882_4921365_-	NADH-quinone oxidoreductase subunit B family protein	NA	NA	NA	NA
WP_168587676.1\|4921468_4921846_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_168587677.1\|4922040_4922211_+	CBS domain-containing protein	NA	NA	NA	NA
WP_168587678.1\|4924477_4924804_+	hypothetical protein	NA	NA	NA	NA
WP_168587679.1\|4925318_4926407_+	hypothetical protein	NA	NA	NA	NA
WP_168587680.1\|4927338_4927665_-	hypothetical protein	NA	NA	NA	NA
WP_168587681.1\|4927925_4928147_+	hypothetical protein	NA	NA	NA	NA
WP_168590299.1\|4928237_4929440_+\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_168587682.1\|4929523_4930402_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_168587683.1\|4931436_4932663_+	hypothetical protein	NA	NA	NA	NA
WP_168587684.1\|4933043_4934051_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_168587685.1\|4934043_4936512_+	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	2.8e-25	23.7
WP_168587686.1\|4936569_4937721_+	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_168587687.1\|4937723_4939277_+	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.5e-08	24.4
WP_168587688.1\|4939273_4940323_+	ABC transporter permease	NA	NA	NA	NA
WP_168587689.1\|4942241_4943036_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_168587690.1\|4943543_4944896_-	MHS family MFS transporter	Q6JIH2	Burkholderia_virus	4.1e-47	31.6
WP_168587691.1\|4945054_4945672_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_168587692.1\|4945824_4946736_+	hypothetical protein	NA	NA	NA	NA
WP_168587693.1\|4946732_4947554_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_168587694.1\|4947550_4949200_+	AMP-binding protein	NA	NA	NA	NA
WP_168590300.1\|4949205_4950423_+	acetyl-CoA C-acetyltransferase	NA	NA	NA	NA
WP_168587695.1\|4950419_4951193_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_168587696.1\|4951265_4952450_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_168587697.1\|4952442_4953408_+	CoA ester lyase	NA	NA	NA	NA
WP_168587698.1\|4953407_4953908_+	MaoC family dehydratase	NA	NA	NA	NA
WP_168587699.1\|4953992_4954880_-	hypothetical protein	NA	NA	NA	NA
WP_168587700.1\|4954935_4955688_-	hypothetical protein	NA	NA	NA	NA
WP_168587701.1\|4955684_4956596_-	hypothetical protein	NA	NA	NA	NA
WP_168587702.1\|4956861_4957659_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_168590301.1\|4957825_4959133_+	MFS transporter	NA	NA	NA	NA
WP_168587703.1\|4959129_4959507_+	hypothetical protein	NA	NA	NA	NA
4959342:4959359	attR	NA	NA	NA	NA
WP_168587704.1\|4959873_4960383_-\|transposase	transposase family protein	NA	NA	NA	NA
4959342:4959359	attR	NA	NA	NA	NA
WP_168587705.1\|4960620_4961055_-\|transposase	transposase	NA	NA	NA	NA
WP_168584120.1\|4961038_4969759_-	hypothetical protein	NA	NA	NA	NA
WP_168587706.1\|4971044_4971500_+\|transposase	transposase	NA	NA	NA	NA
WP_168587707.1\|4972761_4974129_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_168587708.1\|4974154_4975624_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_168587709.1\|4975710_4977561_+	hypothetical protein	NA	NA	NA	NA
WP_168590302.1\|4978508_4979720_+	hypothetical protein	NA	NA	NA	NA
WP_168587710.1\|4979729_4980179_+	hypothetical protein	NA	NA	NA	NA
WP_168590303.1\|4981381_4981804_+	SsgA family sporulation/cell division regulator	NA	NA	NA	NA
WP_168587711.1\|4983854_4984406_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_168587712.1\|4984402_4985107_+	anti-sigma factor	NA	NA	NA	NA
WP_168587713.1\|4985198_4986185_+	DUF1996 domain-containing protein	NA	NA	NA	NA
WP_168587714.1\|4986266_4987187_-	hypothetical protein	NA	NA	NA	NA
WP_168587715.1\|4988131_4988521_+	hypothetical protein	NA	NA	NA	NA
WP_168587716.1\|4988517_4989561_+	AAA family ATPase	A0A059VHA6	Mycobacterium_phage	2.6e-33	35.3
WP_168590304.1\|4990101_4992360_-	LuxR family transcriptional regulator	NA	NA	NA	NA
WP_168587717.1\|4993489_4994521_+	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_168587718.1\|4994581_4996099_+	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.8e-18	29.9
WP_168587719.1\|4996251_4996914_+	FadR family transcriptional regulator	NA	NA	NA	NA
WP_168587720.1\|4997371_4998223_-	xanthine dehydrogenase family protein subunit M	NA	NA	NA	NA
WP_168587721.1\|4998405_4999431_+	ABC transporter permease	NA	NA	NA	NA
WP_168587722.1\|4999427_5000825_+	dihydropyrimidinase	NA	NA	NA	NA
WP_168587723.1\|5000817_5001699_+	carbon-nitrogen hydrolase family protein	NA	NA	NA	NA
WP_168587724.1\|5001718_5003407_+	thiamine pyrophosphate-binding protein	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	1.7e-29	26.1
WP_168587725.1\|5003429_5003906_+	(2Fe-2S)-binding protein	A0A0P0IVM8	Acinetobacter_phage	7.7e-17	34.8
WP_168587726.1\|5003902_5006272_+	xanthine dehydrogenase family protein	NA	NA	NA	NA
WP_168587727.1\|5006268_5006931_+	SRPBCC family protein	NA	NA	NA	NA
WP_168587728.1\|5006927_5007509_+	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_168590305.1\|5007821_5008187_+	hypothetical protein	NA	NA	NA	NA
WP_168587729.1\|5008376_5009057_-\|transposase	transposase	NA	NA	NA	NA
WP_168587730.1\|5009047_5009326_-\|transposase	transposase	NA	NA	NA	NA
WP_168590306.1\|5009945_5012252_-	LuxR family transcriptional regulator	NA	NA	NA	NA
WP_168587731.1\|5012333_5012570_-	hypothetical protein	NA	NA	NA	NA
WP_168587732.1\|5013754_5014765_-	Rieske 2Fe-2S domain-containing protein	NA	NA	NA	NA
WP_168587733.1\|5014769_5016326_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_168587734.1\|5016322_5017060_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_168587735.1\|5017056_5017380_-	lycopene cyclase domain-containing protein	NA	NA	NA	NA
WP_168587736.1\|5017376_5017712_-	lycopene cyclase domain-containing protein	NA	NA	NA	NA
WP_168587737.1\|5017711_5018683_-	phytoene/squalene synthase family protein	NA	NA	NA	NA
WP_168587738.1\|5018679_5020197_-	phytoene desaturase	NA	NA	NA	NA
WP_168587739.1\|5020711_5021881_+	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_168590307.1\|5023042_5024107_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_168587740.1\|5025432_5026161_-	hypothetical protein	NA	NA	NA	NA
WP_168587741.1\|5026210_5027302_-	hypothetical protein	NA	NA	NA	NA
WP_168587742.1\|5028085_5028508_-	hypothetical protein	NA	NA	NA	NA
WP_168587743.1\|5028753_5029035_-	hypothetical protein	NA	NA	NA	NA
WP_168587744.1\|5029084_5029960_-	hypothetical protein	NA	NA	NA	NA
WP_168587745.1\|5030152_5031355_-	PucR family transcriptional regulator	NA	NA	NA	NA
WP_168587746.1\|5031513_5032491_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_168587747.1\|5032504_5034046_+	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	4.1e-27	28.9
WP_168587748.1\|5034042_5034894_+	enoyl-CoA hydratase	NA	NA	NA	NA
WP_168587749.1\|5034929_5036474_+	AMP-binding protein	A0A2H4PQU7	Staphylococcus_phage	1.5e-69	36.7
WP_168587750.1\|5036521_5037286_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_168587751.1\|5037881_5038178_+\|transposase	transposase	A9YX41	Burkholderia_phage	2.0e-07	32.6

DBSCAN-SWA_8

5128486 : 5199499

Bacillus_phage(16.67%)

transposase,integrase,bacteriocin

attL 5151716:5151732|attR 5203656:5203672

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168590312.1\|5128486_5128660_-\|transposase	transposase	NA	NA	NA	NA
WP_168590313.1\|5129011_5129425_+	hypothetical protein	NA	NA	NA	NA
WP_168587776.1\|5129490_5131080_-	PucR family transcriptional regulator	NA	NA	NA	NA
WP_168590314.1\|5131216_5132722_+	CoA-acylating methylmalonate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_168587777.1\|5132734_5134096_+	aspartate aminotransferase family protein	A0A1V0SKB7	Klosneuvirus	7.8e-14	22.3
WP_168587778.1\|5134440_5134791_+	hypothetical protein	NA	NA	NA	NA
WP_168587779.1\|5134860_5136171_-	MHS family MFS transporter	Q6JIH2	Burkholderia_virus	5.6e-33	30.4
WP_168587780.1\|5136206_5136902_-	VOC family protein	NA	NA	NA	NA
WP_168587781.1\|5137158_5138256_-	NADH:flavin oxidoreductase/NADH oxidase	NA	NA	NA	NA
WP_168587782.1\|5138252_5139224_-	amidohydrolase	NA	NA	NA	NA
WP_168587783.1\|5139220_5139661_-	hypothetical protein	NA	NA	NA	NA
WP_168587784.1\|5139702_5140893_-	NAD(P)-binding protein	NA	NA	NA	NA
WP_168590315.1\|5140892_5142194_-	MFS transporter	NA	NA	NA	NA
WP_168590316.1\|5142318_5143746_-	aldehyde dehydrogenase	NA	NA	NA	NA
WP_168590317.1\|5143935_5145696_+	GAF domain-containing protein	NA	NA	NA	NA
WP_168587785.1\|5148749_5148938_+	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_168584121.1\|5148919_5149177_+	hypothetical protein	NA	NA	NA	NA
WP_168590318.1\|5149188_5149518_+	hypothetical protein	S5VXX4	Leptospira_phage	4.1e-09	38.0
WP_168587786.1\|5149654_5149783_-	hypothetical protein	NA	NA	NA	NA
WP_168587787.1\|5149779_5149959_-	hypothetical protein	NA	NA	NA	NA
WP_168587788.1\|5150003_5150285_-	hypothetical protein	NA	NA	NA	NA
WP_168587789.1\|5150741_5152454_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.2e-22	24.6
5151716:5151732	attL	NA	NA	NA	NA
WP_168587790.1\|5152450_5154208_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.1e-27	26.1
WP_168587791.1\|5154204_5160672_-	amino acid adenylation domain-containing protein	A0A2K9KZV5	Tupanvirus	1.8e-47	26.3
WP_168587792.1\|5160668_5160860_-	hypothetical protein	NA	NA	NA	NA
WP_168587793.1\|5160870_5162115_-	DegT/DnrJ/EryC1/StrS family aminotransferase	A0A0P0YLZ6	Yellowstone_lake_phycodnavirus	7.9e-13	27.4
WP_168587794.1\|5162383_5163460_+	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_168587795.1\|5163461_5164613_+	N-methyl-L-tryptophan oxidase	NA	NA	NA	NA
WP_168587796.1\|5164621_5166226_-	(2,3-dihydroxybenzoyl)adenylate synthase	NA	NA	NA	NA
WP_168587797.1\|5166425_5171873_+	amino acid adenylation domain-containing protein	A0A2K9L3I8	Tupanvirus	4.4e-39	27.6
WP_168590319.1\|5171890_5172979_+	NAD(P)H-binding protein	NA	NA	NA	NA
WP_168587798.1\|5175124_5176324_+	cytochrome P450	NA	NA	NA	NA
WP_168587799.1\|5176329_5177112_+	thioesterase	NA	NA	NA	NA
WP_168590320.1\|5177129_5177861_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_168587800.1\|5177857_5179375_+	MFS transporter	NA	NA	NA	NA
WP_168587801.1\|5180029_5181532_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.3e-13	29.7
WP_168587802.1\|5181528_5182332_-	ABC transporter permease	NA	NA	NA	NA
WP_168590321.1\|5182494_5182863_+\|transposase	IS200/IS605 family transposase	I4AZI8	Saccharomonospora_phage	3.2e-31	51.3
WP_168587803.1\|5182859_5183318_+\|transposase	transposase	A0A068A1P5	Thermus_phage	9.4e-12	37.3
WP_168587804.1\|5183362_5184313_-	ABC transporter permease	NA	NA	NA	NA
WP_168587805.1\|5184309_5185860_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_168587806.1\|5185893_5186100_-	ferredoxin	NA	NA	NA	NA
WP_168587807.1\|5186486_5187035_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_168587808.1\|5187047_5188409_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_168587809.1\|5188799_5189006_+	hypothetical protein	NA	NA	NA	NA
WP_168587810.1\|5189002_5189191_+	hypothetical protein	NA	NA	NA	NA
WP_168587811.1\|5189187_5189700_+	hypothetical protein	NA	NA	NA	NA
WP_168587812.1\|5189696_5190023_+	RNA polymerase-binding protein RbpA	NA	NA	NA	NA
WP_168587813.1\|5190082_5190298_+	hypothetical protein	NA	NA	NA	NA
WP_168587814.1\|5190297_5190972_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_168587815.1\|5191007_5191616_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_168587816.1\|5191794_5191980_+	hypothetical protein	NA	NA	NA	NA
WP_168587817.1\|5192539_5192833_+	hypothetical protein	NA	NA	NA	NA
WP_168587818.1\|5193282_5193891_-	hypothetical protein	NA	NA	NA	NA
WP_168587819.1\|5194871_5195648_-\|bacteriocin	bacteriocin biosynthesis protein	NA	NA	NA	NA
WP_168590322.1\|5195665_5196337_-	hypothetical protein	NA	NA	NA	NA
WP_168590323.1\|5196377_5197505_+\|integrase	tyrosine-type recombinase/integrase	A0A220NQQ9	Corynebacterium_phage	1.9e-05	25.6
WP_168587820.1\|5197780_5199499_+\|integrase	site-specific integrase	NA	NA	NA	NA
5203656:5203672	attR	NA	NA	NA	NA

DBSCAN-SWA_9

5912151 : 5925979

Enterobacteria_phage(33.33%)

transposase,integrase

attL 5909399:5909414|attR 5935584:5935599

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
5909399:5909414	attL	NA	NA	NA	NA
WP_168584374.1\|5912151_5912916_+\|transposase	transposase	NA	NA	NA	NA
WP_168588246.1\|5912975_5913173_-	hypothetical protein	NA	NA	NA	NA
WP_168588247.1\|5913206_5913683_-	hypothetical protein	NA	NA	NA	NA
WP_168588248.1\|5914257_5914596_+	hypothetical protein	NA	NA	NA	NA
WP_168588249.1\|5914827_5916624_+	thiamine pyrophosphate-requiring protein	NA	NA	NA	NA
WP_168588250.1\|5918889_5919294_+	hypothetical protein	NA	NA	NA	NA
WP_168588251.1\|5919375_5919933_-	DUF1440 domain-containing protein	NA	NA	NA	NA
WP_168584701.1\|5921384_5921672_+\|transposase	transposase	Q6H9S4	Enterobacteria_phage	3.1e-13	44.4
WP_168590394.1\|5921647_5922367_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_168584700.1\|5922451_5923543_+\|integrase	tyrosine-type recombinase/integrase	A0A2L1ISS9	Mycobacterium_phage	1.4e-10	29.6
WP_168588252.1\|5923502_5925422_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_168584698.1\|5925418_5925718_+	hypothetical protein	NA	NA	NA	NA
WP_168584697.1\|5925781_5925979_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	6.0e-08	45.0
5935584:5935599	attR	NA	NA	NA	NA

DBSCAN-SWA_10

6088270 : 6178876

Mycobacterium_phage(23.08%)

transposase,integrase

attL 6119453:6119473|attR 6125480:6125500

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168590411.1\|6088270_6089929_+\|transposase	IS1182 family transposase	NA	NA	NA	NA
WP_168588369.1\|6090437_6091331_+	dihydrodipicolinate synthase family protein	NA	NA	NA	NA
WP_168588370.1\|6091483_6092176_+	HAD hydrolase-like protein	NA	NA	NA	NA
WP_168585067.1\|6092737_6093688_+	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
WP_168590412.1\|6093918_6094293_-	DUF2075 domain-containing protein	NA	NA	NA	NA
WP_168588371.1\|6094418_6095216_+\|transposase	IS630 family transposase	S5VXX4	Leptospira_phage	6.8e-42	38.3
WP_168588372.1\|6095652_6096660_+	DUF3644 domain-containing protein	NA	NA	NA	NA
WP_168588373.1\|6097168_6097510_-	Lsr2 family protein	A0A218M8U0	Mycobacterium_phage	4.4e-14	44.9
WP_168588374.1\|6097824_6098199_+	Lsr2 family protein	NA	NA	NA	NA
WP_168588375.1\|6098346_6098736_-	hypothetical protein	NA	NA	NA	NA
WP_168584132.1\|6098891_6099305_-	hypothetical protein	NA	NA	NA	NA
WP_168590413.1\|6101033_6101357_-\|transposase	transposase	NA	NA	NA	NA
WP_168588376.1\|6101427_6102513_+\|transposase	transposase	NA	NA	NA	NA
WP_168588377.1\|6102858_6105159_+	LuxR family transcriptional regulator	NA	NA	NA	NA
WP_168590414.1\|6105194_6106925_-\|transposase	IS1182 family transposase	NA	NA	NA	NA
WP_168588378.1\|6107294_6108059_+\|transposase	transposase	NA	NA	NA	NA
WP_168588379.1\|6108360_6109887_-\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_168587652.1\|6109976_6110303_-	hypothetical protein	NA	NA	NA	NA
WP_168590287.1\|6110915_6112145_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	1.8e-33	35.4
WP_168588380.1\|6112870_6113914_-	membrane dipeptidase	NA	NA	NA	NA
WP_168590415.1\|6114059_6115322_-	MFS transporter	NA	NA	NA	NA
WP_168588381.1\|6115569_6117186_-	hydantoinase B/oxoprolinase family protein	NA	NA	NA	NA
WP_168588382.1\|6117182_6119261_-	hydantoinase/oxoprolinase family protein	NA	NA	NA	NA
6119453:6119473	attL	NA	NA	NA	NA
WP_168588383.1\|6120342_6121704_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_168588384.1\|6122899_6125230_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_168588385.1\|6125728_6127030_+	FAD-binding oxidoreductase	NA	NA	NA	NA
6125480:6125500	attR	NA	NA	NA	NA
WP_168588386.1\|6127153_6128371_+	PucR family transcriptional regulator	NA	NA	NA	NA
WP_168588387.1\|6128816_6130202_-\|transposase	IS1380 family transposase	NA	NA	NA	NA
WP_168588388.1\|6130248_6130998_-	hypothetical protein	NA	NA	NA	NA
WP_168588389.1\|6131267_6132215_-	hypothetical protein	A0A2P1N0G0	Streptomyces_phage	3.0e-12	39.6
WP_168588390.1\|6132261_6132459_-	hypothetical protein	NA	NA	NA	NA
WP_168588391.1\|6132445_6132910_-	hypothetical protein	NA	NA	NA	NA
WP_168588392.1\|6132906_6133467_-	hypothetical protein	NA	NA	NA	NA
WP_168588393.1\|6134097_6134481_-	hypothetical protein	NA	NA	NA	NA
WP_168588394.1\|6135112_6135742_-	hypothetical protein	NA	NA	NA	NA
WP_168588395.1\|6135886_6136471_-	hypothetical protein	NA	NA	NA	NA
WP_168588396.1\|6136616_6137657_-\|transposase	IS630 family transposase	S5VXX4	Leptospira_phage	2.8e-56	35.4
WP_168588397.1\|6137693_6137921_-	hypothetical protein	NA	NA	NA	NA
WP_168588398.1\|6138089_6138632_-	hypothetical protein	NA	NA	NA	NA
WP_168588399.1\|6138731_6139322_-	hypothetical protein	NA	NA	NA	NA
WP_168590416.1\|6140117_6141038_+	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_168590397.1\|6144998_6145703_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	1.8e-22	31.8
WP_168589887.1\|6145911_6147495_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_168588400.1\|6148073_6148400_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_168588401.1\|6149532_6151158_+	GMC oxidoreductase	A0A1V0S9J5	Catovirus	1.5e-48	28.0
WP_168590080.1\|6151218_6152715_+\|transposase	IS1380 family transposase	A0A222ZN33	Mycobacterium_phage	5.9e-71	38.9
WP_168590417.1\|6153017_6153728_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	1.8e-06	28.3
WP_168588402.1\|6153818_6155942_+	alpha-galactosidase	NA	NA	NA	NA
WP_168590418.1\|6156097_6157060_+	methyltransferase	NA	NA	NA	NA
WP_168588403.1\|6157097_6158210_-	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_168588404.1\|6159016_6160174_-	3-deoxy-7-phosphoheptulonate synthase	NA	NA	NA	NA
WP_168588405.1\|6160170_6161058_-	glycosyltransferase family 8 protein	NA	NA	NA	NA
WP_168588406.1\|6161198_6161456_-	acyl carrier protein	NA	NA	NA	NA
WP_168588407.1\|6161430_6162891_-	hypothetical protein	NA	NA	NA	NA
WP_168588408.1\|6162925_6164053_-	inositol-3-phosphate synthase	A0A0H4IPK5	Stenotrophomonas_phage	3.6e-73	43.1
WP_168588409.1\|6164635_6165985_+	long-chain fatty acid--CoA ligase	NA	NA	NA	NA
WP_168588410.1\|6166158_6167364_+	cytochrome P450	NA	NA	NA	NA
WP_168588411.1\|6167457_6168438_+	reactive intermediate/imine deaminase	NA	NA	NA	NA
WP_168588412.1\|6168506_6169007_-	hypothetical protein	NA	NA	NA	NA
WP_168588413.1\|6170132_6170528_+	methyltransferase domain-containing protein	A0A1J0MC50	Streptomyces_phage	3.0e-22	49.2
WP_168588414.1\|6170596_6171133_+	hypothetical protein	A0A1J0MC50	Streptomyces_phage	4.0e-22	36.6
WP_168588415.1\|6172573_6174109_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_168588416.1\|6174230_6174791_+	MOSC domain-containing protein	NA	NA	NA	NA
WP_168588417.1\|6175091_6175709_+	iron-sulfur cluster-binding domain-containing protein	NA	NA	NA	NA
WP_168585803.1\|6175908_6177177_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_168590080.1\|6177379_6178876_-\|transposase	IS1380 family transposase	A0A222ZN33	Mycobacterium_phage	5.9e-71	38.9

DBSCAN-SWA_11

6189195 : 6262379

Acinetobacter_phage(12.5%)

transposase,integrase

attL 6220529:6220548|attR 6226682:6226701

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168588427.1\|6189195_6190251_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_168590420.1\|6190247_6190442_-	hypothetical protein	NA	NA	NA	NA
WP_168588428.1\|6191231_6192239_+	DUF3644 domain-containing protein	NA	NA	NA	NA
WP_168588429.1\|6192439_6193957_+	SAM-dependent DNA methyltransferase	J7I0U9	Acinetobacter_phage	2.8e-36	32.6
WP_168588430.1\|6193953_6195156_+	hypothetical protein	NA	NA	NA	NA
WP_168588431.1\|6195190_6198631_+	DEAD/DEAH box helicase family protein	Q6NDX2	Leptospira_phage	1.1e-14	26.5
WP_168588432.1\|6198949_6199486_-	hypothetical protein	NA	NA	NA	NA
WP_168588433.1\|6199775_6199982_-	hypothetical protein	NA	NA	NA	NA
WP_168588434.1\|6199978_6200455_-	hypothetical protein	NA	NA	NA	NA
WP_168588435.1\|6202377_6202749_-	signal peptidase I	NA	NA	NA	NA
WP_168590421.1\|6202733_6204320_-	transcriptional regulator	NA	NA	NA	NA
WP_168588436.1\|6204470_6204854_-	XRE family transcriptional regulator	NA	NA	NA	NA
WP_168588437.1\|6205036_6205249_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_168588438.1\|6205248_6205599_+	WhiB family transcriptional regulator	NA	NA	NA	NA
WP_168588439.1\|6205595_6205928_+	hypothetical protein	NA	NA	NA	NA
WP_168590422.1\|6205960_6206659_+	hypothetical protein	NA	NA	NA	NA
WP_168588440.1\|6206648_6208793_+	cell division protein FtsK	NA	NA	NA	NA
WP_168588441.1\|6208943_6210761_+	recombinase family protein	A0A2K5B2B2	Erysipelothrix_phage	7.5e-12	22.9
WP_168588442.1\|6211152_6211809_-\|transposase	transposase	NA	NA	NA	NA
WP_168588443.1\|6212625_6213390_+	DUF1837 domain-containing protein	NA	NA	NA	NA
WP_168588444.1\|6213397_6216934_+	DEAD/DEAH box helicase	NA	NA	NA	NA
WP_168588445.1\|6217167_6218178_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_168588446.1\|6218913_6219348_-	hypothetical protein	NA	NA	NA	NA
WP_168588447.1\|6219349_6221551_-\|integrase	integrase	NA	NA	NA	NA
6220529:6220548	attL	NA	NA	NA	NA
WP_168588448.1\|6221547_6223635_-	hypothetical protein	NA	NA	NA	NA
WP_168590423.1\|6223634_6225086_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_168590424.1\|6227535_6227934_-	hypothetical protein	NA	NA	NA	NA
6226682:6226701	attR	NA	NA	NA	NA
WP_168590425.1\|6229091_6229967_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_168590426.1\|6230065_6230383_+	hypothetical protein	NA	NA	NA	NA
WP_168590427.1\|6230665_6231379_+	hypothetical protein	NA	NA	NA	NA
WP_168588449.1\|6231406_6232462_+	hypothetical protein	NA	NA	NA	NA
WP_168590428.1\|6232491_6234540_-	recombinase family protein	NA	NA	NA	NA
WP_168588450.1\|6234691_6234943_-	hypothetical protein	NA	NA	NA	NA
WP_168588451.1\|6234945_6236058_+	PrgI family protein	NA	NA	NA	NA
WP_168588452.1\|6236054_6237944_+	DUF87 domain-containing protein	G3MBM1	Bacillus_virus	5.4e-21	25.5
WP_168588453.1\|6237993_6240483_+	type IV secretion system DNA-binding domain-containing protein	NA	NA	NA	NA
WP_168588454.1\|6240570_6241602_+	hypothetical protein	NA	NA	NA	NA
WP_168588455.1\|6241629_6242565_+	M23 family metallopeptidase	A0A2L1IVP0	Streptomyces_phage	1.1e-48	44.5
WP_168588456.1\|6242782_6243541_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_168588457.1\|6245778_6246216_-	hypothetical protein	NA	NA	NA	NA
WP_168588458.1\|6246411_6246765_-	hypothetical protein	NA	NA	NA	NA
WP_168588459.1\|6246881_6248639_-	VWA domain-containing protein	NA	NA	NA	NA
WP_168590429.1\|6248679_6249897_-	AAA domain-containing protein	A0A0K0N7E9	Gordonia_phage	2.6e-45	41.0
WP_168588460.1\|6250596_6250938_-	Lsr2 family protein	Q854K3	Mycobacterium_phage	4.4e-14	44.3
WP_168590430.1\|6251253_6251634_+	Lsr2 family protein	NA	NA	NA	NA
WP_168588461.1\|6251778_6252168_-	hypothetical protein	NA	NA	NA	NA
WP_168588462.1\|6252391_6255337_-	LysM peptidoglycan-binding domain-containing protein	A0A076YP46	Citrobacter_phage	1.0e-05	47.2
WP_168588463.1\|6255333_6255753_-	hypothetical protein	NA	NA	NA	NA
WP_168588464.1\|6255749_6256184_-	pilus assembly protein TadE	NA	NA	NA	NA
WP_168588465.1\|6256180_6256600_-	pilus assembly protein TadE	NA	NA	NA	NA
WP_168588466.1\|6256618_6256852_-	hypothetical protein	NA	NA	NA	NA
WP_168588467.1\|6256900_6257794_-	pilus assembly protein TadB	NA	NA	NA	NA
WP_168588468.1\|6257790_6258639_-	pilus assembly protein TadB	NA	NA	NA	NA
WP_168588469.1\|6258635_6260021_-	CpaF family protein	NA	NA	NA	NA
WP_168588470.1\|6260017_6260830_-	hypothetical protein	NA	NA	NA	NA
WP_168588471.1\|6260865_6261462_-	hypothetical protein	NA	NA	NA	NA
WP_168588472.1\|6261614_6262379_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_12

6283541 : 6320898

Pneumococcus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168588472.1\|6283541_6284306_+\|transposase	transposase	NA	NA	NA	NA
WP_168588493.1\|6285530_6285866_+	hypothetical protein	NA	NA	NA	NA
WP_168588494.1\|6286685_6286880_+	hypothetical protein	NA	NA	NA	NA
WP_168588495.1\|6287010_6288222_+	hypothetical protein	NA	NA	NA	NA
WP_168588496.1\|6288202_6288907_+	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	4.5e-29	39.7
WP_168588497.1\|6288903_6289323_+	6-carboxytetrahydropterin synthase QueD	NA	NA	NA	NA
WP_168588498.1\|6289319_6290075_+	7-carboxy-7-deazaguanine synthase QueE	A0A2P1JXY9	Rhodococcus_phage	1.0e-47	43.5
WP_168588499.1\|6290011_6290578_+	purine phosphoribosyltransferase	NA	NA	NA	NA
WP_168588500.1\|6290561_6291389_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_168590433.1\|6291370_6292108_+	thymidylate kinase	NA	NA	NA	NA
WP_168588501.1\|6292097_6293135_+	radical SAM protein	NA	NA	NA	NA
WP_168588502.1\|6293131_6294244_+	aminotransferase	A0A2K9L0G1	Tupanvirus	1.1e-16	27.6
WP_168588503.1\|6294231_6295104_+	thymidylate kinase	NA	NA	NA	NA
WP_168588504.1\|6295100_6295916_+	HAD family phosphatase	NA	NA	NA	NA
WP_168588505.1\|6295944_6296907_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	NA	NA	NA	NA
WP_168588506.1\|6297021_6297696_+	3'-5' exonuclease	NA	NA	NA	NA
WP_168590434.1\|6297755_6298388_+	DsbA family protein	NA	NA	NA	NA
WP_168588507.1\|6298539_6299100_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_168588508.1\|6299335_6299629_-	hypothetical protein	NA	NA	NA	NA
WP_168588509.1\|6300192_6300378_-	hypothetical protein	NA	NA	NA	NA
WP_168588510.1\|6300551_6301175_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_168588511.1\|6301311_6301671_-	RNA polymerase-binding protein RbpA	NA	NA	NA	NA
WP_168588512.1\|6301667_6302180_-	hypothetical protein	NA	NA	NA	NA
WP_168588513.1\|6302304_6302514_-	hypothetical protein	NA	NA	NA	NA
WP_168588514.1\|6302622_6303036_-	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
WP_168588515.1\|6303322_6304681_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_168588516.1\|6304819_6305335_-\|transposase	transposase	NA	NA	NA	NA
WP_168588517.1\|6305432_6305621_-\|transposase	transposase	NA	NA	NA	NA
WP_168588518.1\|6305984_6306623_-	mycofactocin system transcriptional regulator	NA	NA	NA	NA
WP_168588519.1\|6306701_6306809_+	mycofactocin precursor	NA	NA	NA	NA
WP_168588520.1\|6306808_6307081_+	mycofactocin biosynthesis chaperone MftB	NA	NA	NA	NA
WP_168588521.1\|6307110_6308304_+	mycofactocin radical SAM maturase	NA	NA	NA	NA
WP_168588522.1\|6308330_6309506_+	mycofactocin biosynthesis FMN-dependent deaminase MftD	NA	NA	NA	NA
WP_168590435.1\|6309528_6310299_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_168588523.1\|6310372_6310645_+	creatininase family protein	NA	NA	NA	NA
WP_168588524.1\|6310691_6311933_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_168588525.1\|6312177_6312618_+	creatininase family protein	NA	NA	NA	NA
WP_168590436.1\|6313695_6313932_-	hypothetical protein	NA	NA	NA	NA
WP_168588526.1\|6313957_6314161_-	hypothetical protein	NA	NA	NA	NA
WP_168590437.1\|6314233_6314575_+	response regulator transcription factor	NA	NA	NA	NA
WP_168588527.1\|6314706_6316245_+\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_168588528.1\|6316310_6316790_-	hypothetical protein	NA	NA	NA	NA
WP_168588529.1\|6317087_6317522_-	hypothetical protein	NA	NA	NA	NA
WP_168588530.1\|6317707_6320023_-	AAA family ATPase	NA	NA	NA	NA
WP_168588531.1\|6320658_6320898_+\|transposase	transposase family protein	NA	NA	NA	NA

DBSCAN-SWA_13

6447943 : 6463507

Leptospira_phage(33.33%)

transposase,integrase

attL 6449397:6449413|attR 6467697:6467713

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168588639.1\|6447943_6448798_-\|transposase	IS630 family transposase	S5VXX4	Leptospira_phage	2.3e-51	39.6
WP_168588640.1\|6449301_6449577_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
6449397:6449413	attL	NA	NA	NA	NA
WP_168588641.1\|6450088_6450319_-	hypothetical protein	NA	NA	NA	NA
WP_168588642.1\|6450959_6451478_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_168588643.1\|6451410_6452007_-\|transposase	transposase family protein	NA	NA	NA	NA
WP_168590352.1\|6452356_6453586_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	4.0e-33	34.9
WP_168590453.1\|6454394_6454916_+	RNA polymerase sigma factor	NA	NA	NA	NA
WP_168588644.1\|6454912_6455545_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_168588645.1\|6455754_6456255_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_168588646.1\|6456251_6456590_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_168588647.1\|6456592_6456781_+	hypothetical protein	NA	NA	NA	NA
WP_168588648.1\|6456777_6457254_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_168588649.1\|6457250_6457796_+	hypothetical protein	NA	NA	NA	NA
WP_168588650.1\|6457795_6458368_+	alkaline shock response membrane anchor protein AmaP	NA	NA	NA	NA
WP_168590454.1\|6458720_6458918_-	hypothetical protein	NA	NA	NA	NA
WP_168588651.1\|6459839_6461021_+\|integrase	tyrosine-type recombinase/integrase	A0A0C5AN64	Paenibacillus_phage	9.8e-05	24.2
WP_168590455.1\|6462397_6463507_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
6467697:6467713	attR	NA	NA	NA	NA

DBSCAN-SWA_14

6601952 : 6627153

Paenibacillus_phage(50.0%)

transposase,integrase

attL 6607919:6607936|attR 6630299:6630316

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168590470.1\|6601952_6604883_+\|transposase	Tn3 family transposase	NA	NA	NA	NA
WP_168588764.1\|6604928_6605339_-	RidA family protein	NA	NA	NA	NA
WP_168588765.1\|6606838_6607261_-	hypothetical protein	NA	NA	NA	NA
WP_168588766.1\|6607257_6609177_-\|integrase	integrase	NA	NA	NA	NA
6607919:6607936	attL	NA	NA	NA	NA
WP_168587152.1\|6609596_6610166_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_168588767.1\|6610203_6610392_+	hypothetical protein	NA	NA	NA	NA
WP_168588768.1\|6610905_6613197_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_168590471.1\|6613241_6614417_-\|integrase	site-specific integrase	A0A0C5AN64	Paenibacillus_phage	1.5e-08	24.0
WP_168588769.1\|6614571_6614709_-	hypothetical protein	NA	NA	NA	NA
WP_168588770.1\|6614856_6615297_-	hypothetical protein	NA	NA	NA	NA
WP_168588771.1\|6615293_6616388_-	hypothetical protein	NA	NA	NA	NA
WP_168588772.1\|6616403_6616823_+	recombinase family protein	NA	NA	NA	NA
WP_168588773.1\|6616819_6617137_+	hypothetical protein	NA	NA	NA	NA
WP_132485213.1\|6617336_6618620_+	DUF2236 domain-containing protein	NA	NA	NA	NA
WP_168588774.1\|6618866_6619226_+	hypothetical protein	NA	NA	NA	NA
WP_168588775.1\|6619284_6622404_-\|transposase	Tn3 family transposase	Q1MVP5	Enterobacteria_phage	5.9e-198	40.3
WP_168590472.1\|6622691_6623225_+	hypothetical protein	NA	NA	NA	NA
WP_168588776.1\|6623458_6624034_-	hypothetical protein	NA	NA	NA	NA
WP_168590473.1\|6624445_6624874_-	hypothetical protein	NA	NA	NA	NA
WP_168588777.1\|6625159_6625747_-	G/U mismatch-specific DNA glycosylase	NA	NA	NA	NA
WP_168588778.1\|6626109_6627153_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
6630299:6630316	attR	NA	NA	NA	NA

DBSCAN-SWA_15

7085208 : 7224327

104

Enterobacteria_phage(18.18%)

transposase,integrase,tRNA

attL 7184352:7184372|attR 7223632:7223652

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168589097.1\|7085208_7085787_-\|transposase	transposase	NA	NA	NA	NA
WP_168589098.1\|7086570_7087530_-	PDZ domain-containing protein	NA	NA	NA	NA
WP_168589099.1\|7087771_7088452_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_168589100.1\|7088771_7089605_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_168589101.1\|7089900_7090467_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_168590540.1\|7090479_7090908_+	hypothetical protein	NA	NA	NA	NA
WP_168589102.1\|7091208_7095180_-	HAMP domain-containing protein	A0A1V0SGX0	Hokovirus	7.8e-30	36.9
WP_168589103.1\|7095198_7095855_-	response regulator transcription factor	NA	NA	NA	NA
WP_168589104.1\|7095998_7096418_-	CBS domain-containing protein	A0A2I6B2H4	Macacine_betaherpesvirus	5.3e-38	53.3
WP_168589105.1\|7097077_7097476_-	gas vesicle structural protein GvpA	NA	NA	NA	NA
WP_168589106.1\|7097609_7098134_-	hypothetical protein	NA	NA	NA	NA
WP_168589107.1\|7099829_7100204_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_168589108.1\|7100906_7101779_-	hypothetical protein	NA	NA	NA	NA
WP_168590541.1\|7101969_7102923_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_168589109.1\|7103003_7103516_+	hypothetical protein	NA	NA	NA	NA
WP_168589110.1\|7103499_7104879_+	glutamine synthetase	NA	NA	NA	NA
WP_168589111.1\|7104890_7105811_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_168589112.1\|7105819_7105984_+	DUF2437 domain-containing protein	NA	NA	NA	NA
WP_168589113.1\|7106084_7106573_+	MFS transporter	NA	NA	NA	NA
WP_168589114.1\|7106715_7107375_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_168589115.1\|7107371_7109057_+	hydantoinase B/oxoprolinase family protein	NA	NA	NA	NA
WP_168589116.1\|7109053_7111150_+	hydantoinase/oxoprolinase family protein	NA	NA	NA	NA
WP_168589117.1\|7111388_7111676_+\|transposase	transposase	Q6H9S4	Enterobacteria_phage	1.4e-13	44.4
WP_168589118.1\|7111693_7112005_-	hypothetical protein	NA	NA	NA	NA
WP_168589119.1\|7112001_7112391_-	hypothetical protein	NA	NA	NA	NA
WP_168589120.1\|7112507_7112732_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_168589121.1\|7114488_7115814_-	MHS family MFS transporter	Q6JIH2	Burkholderia_virus	8.9e-55	33.8
WP_168589122.1\|7115936_7117550_-	acyl-CoA synthetase	A0A2H4PQU7	Staphylococcus_phage	8.3e-71	35.1
WP_168589123.1\|7117584_7118388_-	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_168589124.1\|7118561_7119479_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_168589125.1\|7123268_7123415_+	hypothetical protein	NA	NA	NA	NA
WP_168589126.1\|7123944_7124277_-	hypothetical protein	NA	NA	NA	NA
WP_168590542.1\|7124625_7125087_+	SsgA family sporulation/cell division regulator	NA	NA	NA	NA
WP_168589127.1\|7127108_7129607_-	hypothetical protein	NA	NA	NA	NA
WP_168589128.1\|7130192_7131293_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_168589129.1\|7132841_7133672_+\|transposase	transposase family protein	NA	NA	NA	NA
WP_168589130.1\|7135158_7137498_+	LuxR family transcriptional regulator	NA	NA	NA	NA
WP_168589131.1\|7137761_7139288_-\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_168589132.1\|7139377_7139704_-	hypothetical protein	NA	NA	NA	NA
WP_168587152.1\|7141472_7142042_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_168589133.1\|7142079_7142232_+	hypothetical protein	NA	NA	NA	NA
WP_168589134.1\|7142306_7142594_+	hypothetical protein	NA	NA	NA	NA
WP_168589135.1\|7142756_7142945_+	hypothetical protein	NA	NA	NA	NA
WP_168589136.1\|7143962_7144190_-	hypothetical protein	NA	NA	NA	NA
WP_168590543.1\|7144197_7144650_-	UDP-N-acetyl glucosamine 2-epimerase	NA	NA	NA	NA
WP_168589137.1\|7144701_7145121_-	hypothetical protein	NA	NA	NA	NA
WP_168589138.1\|7145143_7146442_+\|transposase	transposase	NA	NA	NA	NA
WP_168589139.1\|7146657_7147587_-\|transposase	IS1380 family transposase	NA	NA	NA	NA
WP_168588383.1\|7147641_7149003_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_168589140.1\|7149009_7149531_-	hypothetical protein	NA	NA	NA	NA
WP_168589141.1\|7149618_7150365_-	hypothetical protein	NA	NA	NA	NA
WP_168589142.1\|7151056_7151845_+	DUF1698 domain-containing protein	NA	NA	NA	NA
WP_168589143.1\|7153752_7154019_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_168589144.1\|7153922_7154318_+	hypothetical protein	NA	NA	NA	NA
WP_168589145.1\|7155047_7155839_-	M15 family metallopeptidase	NA	NA	NA	NA
WP_168589146.1\|7155835_7156933_-	DUF917 domain-containing protein	NA	NA	NA	NA
WP_168589147.1\|7156935_7158498_-	hydantoinase/oxoprolinase family protein	NA	NA	NA	NA
WP_168589148.1\|7158548_7159904_-	cytosine permease	NA	NA	NA	NA
WP_168589149.1\|7160032_7161112_+	DUF917 domain-containing protein	NA	NA	NA	NA
WP_168589150.1\|7161108_7162656_+	hypothetical protein	NA	NA	NA	NA
WP_168589151.1\|7162772_7165322_-	hypothetical protein	NA	NA	NA	NA
WP_168589152.1\|7165450_7166749_+	amidohydrolase family protein	NA	NA	NA	NA
WP_168589153.1\|7166745_7167240_+	tripartite tricarboxylate transporter TctB family protein	NA	NA	NA	NA
WP_168589154.1\|7167245_7168742_+	tripartite tricarboxylate transporter permease	NA	NA	NA	NA
WP_168589155.1\|7168789_7169785_+	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_168589156.1\|7169781_7169973_+	hypothetical protein	NA	NA	NA	NA
WP_168589157.1\|7169959_7171387_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_168589158.1\|7171373_7172792_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_168589159.1\|7174739_7175033_-	muconolactone delta-isomerase	NA	NA	NA	NA
WP_168590544.1\|7175029_7176595_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_168590545.1\|7176603_7177593_-	dipeptidase	NA	NA	NA	NA
WP_168590546.1\|7177667_7179113_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_168589160.1\|7179261_7180920_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.5e-19	31.6
WP_168589161.1\|7180916_7181996_-	LacI family transcriptional regulator	C6ZCU4	Enterobacteria_phage	4.2e-18	23.8
WP_168589162.1\|7182078_7183029_-	ABC transporter permease	NA	NA	NA	NA
WP_168590547.1\|7183039_7183834_-	ABC transporter permease	NA	NA	NA	NA
WP_168589163.1\|7183957_7184680_-	decarboxylase	NA	NA	NA	NA
7184352:7184372	attL	NA	NA	NA	NA
WP_168589164.1\|7185201_7186776_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_168590548.1\|7186983_7187679_+	hypothetical protein	NA	NA	NA	NA
WP_168589165.1\|7187590_7188457_-	hypothetical protein	NA	NA	NA	NA
WP_168589166.1\|7188507_7188831_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_168589167.1\|7190518_7191322_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_168588765.1\|7192019_7192442_-	hypothetical protein	NA	NA	NA	NA
WP_168590549.1\|7192438_7192855_-	hypothetical protein	NA	NA	NA	NA
WP_168589168.1\|7194480_7195533_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_168589169.1\|7196225_7196747_-	hypothetical protein	NA	NA	NA	NA
WP_168590550.1\|7196803_7197913_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_168588651.1\|7199288_7200470_-\|integrase	tyrosine-type recombinase/integrase	A0A0C5AN64	Paenibacillus_phage	9.8e-05	24.2
WP_168590551.1\|7201165_7203355_+\|integrase	phage integrase family protein	A0A1P8DJJ6	Virus_Rctr41k	4.3e-06	24.9
WP_168589170.1\|7204272_7205097_+	hypothetical protein	NA	NA	NA	NA
WP_168589171.1\|7205909_7207181_-	hydantoinase/carbamoylase family amidase	NA	NA	NA	NA
WP_168589172.1\|7207177_7208311_-	diaminopropionate ammonia-lyase	NA	NA	NA	NA
WP_168589173.1\|7208450_7208666_+	hypothetical protein	NA	NA	NA	NA
WP_168589174.1\|7208671_7210111_-	sodium:solute symporter family protein	NA	NA	NA	NA
WP_168589175.1\|7210138_7211290_-	YgeY family selenium metabolism-linked hydrolase	NA	NA	NA	NA
WP_168589176.1\|7211291_7212869_-	amidohydrolase family protein	NA	NA	NA	NA
WP_168589177.1\|7213724_7214450_-	hypothetical protein	NA	NA	NA	NA
WP_168589178.1\|7214737_7215526_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_168589179.1\|7215941_7216547_-	aspartate/glutamate racemase family protein	NA	NA	NA	NA
WP_168589180.1\|7216597_7217995_-	dihydropyrimidinase	NA	NA	NA	NA
WP_168589181.1\|7218481_7219984_-	NCS1 family nucleobase:cation symporter-1	NA	NA	NA	NA
WP_168589182.1\|7220930_7222211_-	GNAT family N-acetyltransferase	R4TQL5	Phaeocystis_globosa_virus	3.0e-15	30.4
WP_168589183.1\|7222465_7223038_-	alkaline shock response membrane anchor protein AmaP	NA	NA	NA	NA
WP_168590287.1\|7223097_7224327_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	1.8e-33	35.4
7223632:7223652	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP040605

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection