CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_AP022642	Pseudomonas otitidis strain MrB4	1 crisprs	csa3,DEDDh,DinG,cas3,WYL	0	0	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_AP022642_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP022642_1

4836960-4837061

Orphan

Consensus_repeat	Method
CCCAGGGAAATGGTGCGGGGCAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP022642_1

>merge|NZ_AP022642|1|4836960-4837061|CRISPRCasFinder
CCCAGGGAAATGGTGCGGGGCATCCCGGACTGAAGTCCGGGCTACAGGCAGCACCCTGCCCCCGTAGCCTGGGCTTCAGCCCAGGGAAATGGCGCGGGGCAT

>NZ_AP022642|1|1|4836960-4837061|CRISPRCasFinder
CCCAGGGAAATGGTGCGGGGCAT	CCCGGACTGAAGTCCGGGCTACAGGCAGCACCCTGCCCCCGTAGCCTGGGCTTCAG
CCCAGGGAAATGGCGCGGGGCAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP022642.1\|WP_172434524.1\|4843734_4844898_+\|PepSY-domain-containing-protein	unknown	unknown	gnl\|CDD\|225723
NZ_AP022642.1\|WP_107331293.1\|4833340_4833802_-\|response-regulator	unknown	unknown	gnl\|CDD\|381108
NZ_AP022642.1\|WP_139233625.1\|4827481_4827964_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP022642.1\|WP_139233626.1\|4826491_4826776_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP022642.1\|WP_172434522.1\|4840482_4841907_-\|cytosine-permease	unknown	unknown	gnl\|CDD\|224374
NZ_AP022642.1\|WP_172435139.1\|4826844_4827468_+\|DUF4241-domain-containing-protein	unknown	unknown	gnl\|CDD\|379427
NZ_AP022642.1\|WP_107331290.1\|4838356_4839388_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270307
NZ_AP022642.1\|WP_172434519.1\|4836300_4836660_-\|DUF3509-domain-containing-protein	unknown	unknown	gnl\|CDD\|338217
NZ_AP022642.1\|WP_074970958.1\|4845421_4845730_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375438
NZ_AP022642.1\|WP_172434516.1\|4830332_4830920_-\|biliverdin-producing-heme-oxygenase	unknown	unknown	gnl\|CDD\|350857
NZ_AP022642.1\|WP_172434526.1\|4845754_4847470_-\|single-stranded-DNA-specific-exonuclease-RecJ	unknown	unknown	gnl\|CDD\|182944
NZ_AP022642.1\|WP_172434517.1\|4830916_4833304_-\|response-regulator	unknown	unknown	gnl\|CDD\|237425
NZ_AP022642.1\|WP_044400048.1\|4843222_4843525_+\|DUF1883-domain-containing-protein	unknown	unknown	gnl\|CDD\|378107
NZ_AP022642.1\|WP_172434515.1\|4828634_4829873_+\|NADH:flavin-oxidoreductase/NADH-oxidase-family-protein	unknown	unknown	gnl\|CDD\|240084
NZ_AP022642.1\|WP_172434525.1\|4844894_4845425_+\|thiamine-pyrophosphate-binding-protein	unknown	unknown	unknown
NZ_AP022642.1\|WP_172434521.1\|4839649_4840486_-\|carbon-nitrogen-hydrolase	unknown	unknown	gnl\|CDD\|143604
NZ_AP022642.1\|WP_172434514.1\|4828108_4828534_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133413
NZ_AP022642.1\|WP_172434520.1\|4837101_4838208_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223652
NZ_AP022642.1\|WP_172434523.1\|4842143_4842980_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|336409
NZ_AP022642.1\|WP_172434518.1\|4833808_4836076_-\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|226702

Protein	Function_ID	Function_description	E-value
NZ_AP022642.1\|WP_172434524.1\|4843734_4844898_+\|PepSY-domain-containing-protein	gnl\|CDD\|225723	COG3182, PiuB, Uncharacterized iron-regulated membrane protein [Function unknown].	1.48715e-73
NZ_AP022642.1\|WP_107331293.1\|4833340_4833802_-\|response-regulator	gnl\|CDD\|381108	cd17557, REC_Rcp-like, phosphoacceptor receiver (REC) domain of cyanobacterial phytochrome response regulator Rcp and similar domains. This family is composed of response regulators (RRs) that are members of phytochrome-associated, light-sensing two-component signal transduction pathways such as Synechocystis sp. Rcp1, Tolypothrix sp. RcpA, and Agrobacterium tumefaciens bacteriophytochrome response regulator AtBRR. They are stand-alone RRs containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. Also included in this family us Methanosaeta harundinacea methanogenesis regulatory protein FilR2, also a stand-alone RR. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	6.46952e-60
NZ_AP022642.1\|WP_172434521.1\|4839649_4840486_-\|carbon-nitrogen-hydrolase	gnl\|CDD\|143604	cd07580, nitrilase_2, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	2.08552e-117
NZ_AP022642.1\|WP_172434522.1\|4840482_4841907_-\|cytosine-permease	gnl\|CDD\|224374	COG1457, CodB, Purine-cytosine permease and related proteins [Nucleotide transport and metabolism].	6.77473e-100
NZ_AP022642.1\|WP_172435139.1\|4826844_4827468_+\|DUF4241-domain-containing-protein	gnl\|CDD\|379427	pfam14025, DUF4241, Protein of unknown function (DUF4241). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 205 and 315 amino acids in length. There is a conserved GDG sequence motif at the C-terminus.	6.11048e-56
NZ_AP022642.1\|WP_107331290.1\|4838356_4839388_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270307	cd13589, PBP2_polyamine_RpCGA009, The periplasmic-binding component of an uncharacterized ABC transport system from Rhodopseudomonas palustris CGA009 and related proteins; contains the type 2 periplasmic-binding fold. This group represents the periplasmic binding domain that serves as the primary high-affinity receptor of an uncharacterized ABC-type polyamine transporter from Rhodopseudomonas palustris Cga009 and related proteins from other bacteria. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.10247e-79
NZ_AP022642.1\|WP_172434519.1\|4836300_4836660_-\|DUF3509-domain-containing-protein	gnl\|CDD\|338217	pfam12021, DUF3509, Protein of unknown function (DUF3509). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 92 to 110 amino acids in length. This protein has two completely conserved residues (G and R) that may be functionally important.	3.29995e-05
NZ_AP022642.1\|WP_074970958.1\|4845421_4845730_+\|hypothetical-protein	gnl\|CDD\|375438	pfam17936, Big_6, Bacterial Ig domain. This domain is found in a wide variety of extracellular bacterial proteins often in multiple tandem copies.	0.00730987
NZ_AP022642.1\|WP_172434516.1\|4830332_4830920_-\|biliverdin-producing-heme-oxygenase	gnl\|CDD\|350857	cd19166, HemeO-bac, heme oxygenase found in pathogenic bacteria. This subfamily contains bacterial heme oxygenase (HO, EC 1.14.14.18), where HO is part of a pathway for iron acquisition from host heme and heme products. Most of these proteins have yet to be characterized. HO catalyzes the rate limiting step in the degradation of heme to biliverdin in a multi-step reaction. HO is essential for recycling of iron from heme which is used as a substrate and cofactor for its own degradation to biliverdin, iron, and carbon monoxide. This family includes heme oxygenase (pa-HO) from Pseudomonas aeruginosa, an opportunistic pathogen that causes a variety of systemic infections, particularly in those afflicted with cystic fibrosis, as well as cancer and AIDS patients who are immunosuppressed. Pa-HO, expressed by the PigA gene, is critical for the acquisition of host iron since there is essentially no free iron in mammals, and is unusual since it hydroxylates heme predominantly at the delta-meso heme carbon, while all other well-studied HOs hydroxylate the alpha-meso carbon. Also included in this family is Neisseria meningitidis HO which is substantially different from the human HO, with the reaction product being ferric biliverdin IXalpha rather than reduced iron and free biliverdin IXalpha. HO shares tertiary structure similarity to methane monooxygenase (EC 1.14.13.25), ribonucleotide reductase (EC 1.17.4.1) and thiaminase II (EC 3.5.99.2), but shares little sequence homology.	4.99386e-37
NZ_AP022642.1\|WP_172434526.1\|4845754_4847470_-\|single-stranded-DNA-specific-exonuclease-RecJ	gnl\|CDD\|182944	PRK11070, PRK11070, single-stranded-DNA-specific exonuclease RecJ.	0
NZ_AP022642.1\|WP_172434517.1\|4830916_4833304_-\|response-regulator	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	3.63338e-120
NZ_AP022642.1\|WP_044400048.1\|4843222_4843525_+\|DUF1883-domain-containing-protein	gnl\|CDD\|378107	pfam08980, DUF1883, Domain of unknown function (DUF1883). This domain is found in a set of hypothetical bacterial proteins.	1.01477e-41
NZ_AP022642.1\|WP_172434515.1\|4828634_4829873_+\|NADH:flavin-oxidoreductase/NADH-oxidase-family-protein	gnl\|CDD\|240084	cd04733, OYE_like_2_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 2. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0
NZ_AP022642.1\|WP_172434514.1\|4828108_4828534_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133413	cd04786, HTH_MerR-like_sg7, Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily. Putative helix-turn-helix (HTH) MerR-like transcription regulators (subgroup 7) with a conserved cysteine present in the C-terminal portion of the protein. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	3.22167e-51
NZ_AP022642.1\|WP_172434520.1\|4837101_4838208_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|223652	COG0579, COG0579, Predicted dehydrogenase [General function prediction only].	4.7764e-108
NZ_AP022642.1\|WP_172434523.1\|4842143_4842980_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|336409	pfam06445, GyrI-like, GyrI-like small molecule binding domain. This family contains the small molecule binding domain of a number of different bacterial transcription activators. This family also contains DNA gyrase inhibitors. The GyrI superfamily contains a diad of the SHS2 module, adapted for small-molecule binding. The GyrI superfamily includes a family of secreted forms that is found only in animals and the bacterial pathogen Leptospira.	8.74732e-36
NZ_AP022642.1\|WP_172434518.1\|4833808_4836076_-\|GAF-domain-containing-protein	gnl\|CDD\|226702	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms].	0

>NZ_AP022642.1|WP_172434519.1|4836300_4836660_-|DUF3509-domain-containing-protein
MQIAIKEFFDAFPGYEVSIRPRPDGMLLLTLGKDGEEPLRKAIPSDAVFCTERVRGVIREMQREMKLASGEVTWKGEGDTWLDRELPTFSGGPIHMTAAKTLVERRRLELLNARRAVAS
>NZ_AP022642.1|WP_172434518.1|4833808_4836076_-|GAF-domain-containing-protein
MTPIDSTEDLAAATEACAKEPIHIPGSIQPHGFMLVFDEGRGCVVQASENVQDWLGLPASELIGLPFERLFEHAAVLQGRLQGLALEDPNPFHLGDVRFAIGQERSLPVAMMVHRHDQVLIAEFEPASDAIAAYGNFYPLVRSFVARLQDADNVDELCRHAVQEMKCITGFGRVKAYRFDAEGNGLVLAEEADEGYPRYLGLCFPASDIPPQARALYRANRIRVIEDAHYTPSPLYPAQNPLTGRPLDLSFAALRSVSPVHLQYMRNMGTLASMSVSIVVRGELWGLISCHDLHPRGVGFQTRTACEMLGSVLSLQIESREAHDRTEHLLSLRQHIVQMLSAMADRDSISGGLLAQPETFLGFAKASGAAIISAARCDLVGETPPQAQVTALVHWLARRPGINVFHSDNVGRDIDELPELARHAAGVLAVAISQIHSHYLVWFKPEQARTVEWAGRPEKSVDPSGGLSPRHSFERWQQTVRGYSSPWDPLEIEGVWELRTAVLGIVLRKAEEMAALASELKKSNKELEAFSYSVSHDLRAPLRHIAGYAELLGEFEGSRLSERGLRFLDHIGESARFAGTLVDNLLSFSQMGRAALRFSDVDLQALVDAILKEMEPDLVGRNIQWHIAGLPTLIADAAFLHLAMRNLLANAVKYSRDRDPAVIEVSARTEGDEVVVTVSDNGVGFDMAYAGKLFGVFQRLHRMEEFEGTGIGLASVRRIIERHDGRVWAEGRVGEGARFHFALPLRAQHSQLPTE
>NZ_AP022642.1|WP_107331293.1|4833340_4833802_-|response-regulator
MLKPILLVEDNPHDLELTLVALERSQLANDVVVMRDGADALDYLLRRNHYAQRDDGNPAVLLLDLKLPKVDGLEVLKAVRETPELRSIPTVMLTSSREEPDLQRAYELGVNAYVVKPVEFKEFVTAISDLGVFWAVLNEPPPGSLRLQRRPGS
>NZ_AP022642.1|WP_172434517.1|4830916_4833304_-|response-regulator
MPQTPLKLLLVEDSPRDAELALLILERSGLEVDSTLVYHHAGVEQALAAATFDLILCDFILPGSSGAQALEVARRLAPKTPFIFLSGVFGEEHAVEMMRQGAVDYVLKQNLSLLPKAVGRALAEVRERERRRRAEEALMEVEVRARLAIDAARMGMWDYNPQTGRLLWDERCKALYELPRDAEVDLVTFFDRCHPKDRPLLERKVQEALAVDSGNEYQAEYRVQLPGGRERWVLTSGRAFFEAGRCVRFIGVLQDISEQKYATEALQRLNEMLGERVERRTRERDRTWELSRELLAVMRFDMTPIALNPAWEDTLGLTREQLTRVQLWQLIHPDDIEATLRETESVADGNVSTRFVNRMRHTDGDYRWLSWTIVPDEGLMYAAVRDITGERAVLDELAATNQRLREQIRERERIEATLQQMQRLEAIGQLTAGVAHDFNNLLTVILTSATFLERDVERGNHERILGRLHNIREAGERGAKLTGQLLAFSRRQRLEPVPVNLNDTLQGLLELLQRTLGGGIWVETHTAPDLWRALVDPTQTEMIILNLAINARDAMPQGGTLRLVTANEVVQAAAQRPEDPEPGPYVVLSIEDTGVGMTEEVLAKAFEPFFTTKEVGKGSGLGLAQVFGFAKQSGGGVSIHTEPGRGTRVKVYLPCIHDDSGEACAERPAAVPVPGPSSTARTILLVDDDPRVREVTAALLESLGYRVLEVGSGSEALQRLEQGVDLLLTDYAMPGMNGAELANLAQQQRPDLPVIFITGYAELGGLDLPDQVVVQKPFREADIAAKLRAALEERP
>NZ_AP022642.1|WP_172434516.1|4830332_4830920_-|biliverdin-producing-heme-oxygenase
MRVREHLRQAGAPWHEAVDAAFSRFDLSQADGYRAFLRAHARALPGLEQALEQAGIAQLVPDWPARRRRHALLADLADLGLSPPPTAAPCLDAKPGLLWGLAYVLEGSRLGGRLLARQVTGAQADLPVRYLGHGQDQPLWPDFLRQLEAHAHDLPEADLEQGVILGFRHFLNAAEPPAEQSAGCAELGEPHRIPA
>NZ_AP022642.1|WP_172434515.1|4828634_4829873_+|NADH:flavin-oxidoreductase/NADH-oxidase-family-protein
MSPFQPLSLPNGTTLPNRIAKASMEENLADPLQAPSDALMRLYAAWAEGGVGLLLSGNVMVDARAMTGPGGVVLEDDRQLPRFREWATVGKAHGAQFWLQLNHPGRQMQANLGQATVAPSAVALEMGSLSRMFPTPRALEEQDIAALIERFATSAVLAEQAGFDGVQIHAAHGYLLSQFLSPLTNRRQDRWGGSLENRARLLLEVVKAVRARVSPRFGVGVKLNSADFQRGGFEPQDARQVLLWLNDLPVDLVELSGGSYEAPAMQGDARDGRTLAREAYFLEFARELATEARMPVMVTGGIRRLPVVEQVLASGVSLAGIATALALDPALPRRWREGDNAASAELPPIRWRNKSLAALAYMSAVKYQMRRLGDGQSPRPGVSPLRALLKEQWHTLHRTRHYRRLMAERSEG
>NZ_AP022642.1|WP_172434514.1|4828108_4828534_-|MerR-family-transcriptional-regulator
MKIGELARRSGLTASRIRFYEASGLIAAQRLGNGYRDYPEQALAVLELIACGQQAGFSLEEMRHLLPSPGQVHGNHERMLEGLRRKVAEIEAMQARLVVARERLLQVIDSIEDKPEGMGCQENAERVLGRLRSGTQPLPQR
>NZ_AP022642.1|WP_139233625.1|4827481_4827964_-|hypothetical-protein
MALSTGAAWAGALPDPQASGAAAKAPAVLEHYAGALGCSFSMPVKTLVPFTVVEPATLEEHPLYLALFQVDEGCVGDASAVRTHIAALQPARNGGLYVVPGYSQTSPYLPQRIDRLFVEGEALRYTGQASLDPANPEPQAGQLSQEGGRWIDANLEPLGD
>NZ_AP022642.1|WP_172435139.1|4826844_4827468_+|DUF4241-domain-containing-protein
MNHPPFDAAFAEGYQVKVEGIDYRFYTQPIGELELPTGQLVACDPLVSCDAPFTQAVPKGRFPLQLAIARIGEDERIAFARIVFAPGAATRWEMALVDGQDPSTLGPDEFFGYGVDSGTGGFMDAAALRRYEAQREQEGEAFDERLLAELDTTYRHTRSWTLLPTEAGNVALFSSGYGDGAYPSYFGYDASGRLVAVVTDFLLLPWH
>NZ_AP022642.1|WP_139233626.1|4826491_4826776_+|hypothetical-protein
MPSDQALAHLVARFGSMAPDHPWSEEPSLWVLDAGEQPIKVFALLRLAAQLTPAQARERMQTGRFRVLNASSYELKRWHELFTAAGAHLEYRCE
>NZ_AP022642.1|WP_172434520.1|4837101_4838208_-|NAD(P)/FAD-dependent-oxidoreductase
MAVDIECVVVGAGVVGLAVARALAQAGREVVIVEAADAIGTGISSRNSEVIHAGIYYPAGSLKARLCVDGRHRLLAFCRSHGVAVQQLGKLIVATDDAQVAPLQALLARGLANGVDDLRLLSRDQALALEPDLHCVAALHSPSTGIVDSHGLMLALLGDAEAAGAALALGSPLLSAQVQGDGFQLTVGGASPTTLGCRLLVNAAGLGAPGLAGRIDGLPAAHVPRGYLCKGHYFSLAGRAPFSRLVYPAPEAAGLGVHMTLDLGGQARFGPDVQWTDTEDYQVDPRRADGFYAAIRRYWPGLPDGALQPDYAGIRPKISSPDEPAADFRISGPEDHGIVGLVNLFGIESPGLTSSLAIADVVRQALER
>NZ_AP022642.1|WP_107331290.1|4838356_4839388_-|ABC-transporter-substrate-binding-protein
MVVAVRRALGLALAVTCLPASADFVTVITFGGANKDVQKEAFFKPFKASTGDAVVHGSYNGDLDKLKSMIDISHVTWDVVEVEAPELARGCEEGLFEKIDPALVGNPSDFVAGALQPCGVGIFVWSTVLAYDSARIKDAPRGWADFWDLRKYPGKRGLRHGAKYNLEFALMADGVAPNEVYQVLDTPAGVDRAFRKLDEIKSSVVWWKSGAEPVRALQDGKVAMSSAYNGRIATAQKETRSLAMAWGGNIYDFDYWALPKGSWKGELAKKFVHFVSQPDQQKAFAEGISYSPVNNKAIAMINPAIAATLPTAPQNIRDALPMNVTFWAAHADLEARFENWVKN
>NZ_AP022642.1|WP_172434521.1|4839649_4840486_-|carbon-nitrogen-hydrolase
MNTRPVAPVKVACCQVAPRIGELAHNRALAEGAIRRAALEGAHIIVLPELVQSGYLFRDKAEALALSEPLDGPAVSHWQALARELGVVIAAGFCERRDDGELANSAVLVDPDGLRAHYRKAHLWDAEKALFIPGDAAPPVVDTVHGRLGLMICYDLEFPEWVRLPALAGAQLLCAPVNWPLGPRPQGERPAEVVRVQANAAVNRMFIAACDRHGHERGQDWVQGSVIVDADGFPLASPVEGGERLLLATLDLAQADDKRISARNDVHGDRRPALYQAP
>NZ_AP022642.1|WP_172434522.1|4840482_4841907_-|cytosine-permease
MTQQHDARPMIEVRSIDYVPRHERHGKVWHQGPFWFTGNFVLTTLVTGFTGPALGLGALGSILAILIGVCIGTFFMAFHANQGPRMGLPQMIQSRPQFGVRGAVVPFLAVVFVYIGFNVFNVILATDAINTVLPGARTPWYVLLVGLAVLLAIVGHDLLHAVQRWLTWLMIAVFGALTLFAVTQLSADAALQGSGFSWSAFLVQLSAAAGYQISYSVYVSDYSRYLPEETPAGKVIFWTYLGAGASALWLMSLGAFLASALPAPDAIGSVRELGNQLHDGFGTLIVLVAVPSLVGIMAVNCYGAMLTGLSALDAFSRVRPTLGVRVAGISVVALVILLVARMIPESYLGSFNTFVLLMLYFLVPWTAVNLVDFYLVRKGRYAIAEIFNPEGVYRGWSRPGLVAYGLGLLAMVPFMSLSFWSGPFATALGGADIAFAIGLPVAGLAYWLQCRHQDRSEEERLAALDPQRLEDPRP
>NZ_AP022642.1|WP_172434523.1|4842143_4842980_-|AraC-family-transcriptional-regulator
MKPETLAHYARRIDPVLRWLAAHPDADPDLHHLAELACLSPYHFHRVYRAMLGETVNATAQRLRMHRAAVALAGTGDSLERVGRRAGYSSHAAFNRAFGAHFGLPPGRYRETRARPLAPQELAMYPIAIETFPGAVLATLPHQGSYQGIGPLFGRAFMLAMGQGLLGPDCLMYGVYFDDPAQVPEARLRSLAGISVSPQAVIGGELERYEIPAGRCAMLTYTGPYNEMGKAYDWLYSRWLPESGLEPGDCPMFEQYLNDPRSTPPAQLQTRICMMLAG
>NZ_AP022642.1|WP_044400048.1|4843222_4843525_+|DUF1883-domain-containing-protein
MKFIHQREHLNEGDLVVIECSQVCNIRLMSDANFRSFKNGGRHTYHGGAFDRFPARITVPSTGFWNITIDTVTRRAISVTRKPTLKHSIKFVRRSSSHMG
>NZ_AP022642.1|WP_172434524.1|4843734_4844898_+|PepSY-domain-containing-protein
MSKKSRSRTWFLVHSWLALPIWFFVFLVCATGTLAVLSEEIIWLANPDVRATRPADDAQPLGFDQVVAAIARQQPDAAIEWLAKPEEDHFALTAAVSYPDTRTATLYVNPYTGVIQGSSPLFDFRQFTRALHGWWLVPFTNGYSWGWYLVSLLALPMLASLVTGLVVYKRFWRGFLRPTLRIRQGARIFWGDFHRLVGIWSIWFIAVIAVTGTWFLIRAVLYDNHISISSEGPPTLIAREALPRPEPGQPVPRIGVDQAVEVATRTIPGFEVSFVIFPADAFTPLEVGGRGWYPLMFQTAEVNPYDGTLLGSHLLGDRNALEFVTESMRPLHTGDFGGIWVKLLWFVFGLLLTMMVLSGLLIWSKRTVLATAKAMKRPPRPATEVTE
>NZ_AP022642.1|WP_172434525.1|4844894_4845425_+|thiamine-pyrophosphate-binding-protein
MNAPVRSRPARLWLRWRFHLSALLVLIPLGYMPAYFHEASLERGLQGLGERSIGELAVGPWRVRLAEWERGEPVREGKAGYMKDFSLAFCRECDAAIKAAYLRVGKPRYLRAAGALASGSPYRRLAEVRIPEDAPADAELWLTVEGWDGSVHQAALPLAQASPDVVAWLGKRGGGR
>NZ_AP022642.1|WP_074970958.1|4845421_4845730_+|hypothetical-protein
MKRWLGALLLLAGGNAWGHGIYCECQALDATQVRCVGGLSDGTATPGATLDVLDDEGQVLIHGTLGEDSSFTFERPSGAFHVLLELGPGHTAEVEPEAIRPR
>NZ_AP022642.1|WP_172434526.1|4845754_4847470_-|single-stranded-DNA-specific-exonuclease-RecJ
MRIEPRPLPATLPDLGNLPPLLTRLYAARGVSCAEELDKGLARLIPYTQMKGIDAAVTLLVEALEQRQRILFVGDFDADGATASCVGVLGLRMLGAAHVDYLVPNRFEYGYGLTPEIVAVALQREPQLLVTVDNGISSVDGVAAAKAAGLKVLVTDHHLPGPELPAADAIVNPNQPGCEFPSKSMAGVGVIFYVLLALRARLRELDWFARRGMAEPNLAELLDLVALGSVADVVPLDANNRILVHQGLARIRAGRARPGLKALLEVAGRPAARITSTDLGFILGPRLNAAGRLDDMSLGIECLLCEDHALAQDMAVELDQLNQDRKQIEQGMQREALAQLKDLPLEDLPFGLCLFEPDWHQGVIGILASRLKERYHRPTIAFADAGDGLLKGSARSVPGFHIRDALDAVAARHPGLISKFGGHAMAAGLSLPVEHFGAFASAFDAEVRRQLTEDDLTGRLLSDGQLSLQEFHLELARALRQAGPWGQHFPEPLFHGVFQIAQQRLVGERHLKLVLKSECGSLQLDGIAFNIDRDVWPNPTVRWAELAYRLDVNEFRGQESVQLMVVHIAPR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

442825 : 515926

Vibrio_phage(25.0%)

transposase,holin

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_172432384.1\|442825_443275_-\|transposase	transposase	NA	NA	NA	NA
WP_172432385.1\|443438_445631_-	TIGR01666 family membrane protein	NA	NA	NA	NA
WP_172432386.1\|445871_446606_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_172432387.1\|446636_447869_-	diguanylate cyclase	NA	NA	NA	NA
WP_044409275.1\|447944_449324_-	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	7.1e-47	30.3
WP_172432388.1\|449411_450824_-	multidrug transporter subunit MdtD	NA	NA	NA	NA
WP_172432389.1\|450947_451979_+	TMAO reductase system periplasmic protein TorT	NA	NA	NA	NA
WP_172432390.1\|452014_453700_-\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	3.9e-55	30.7
WP_172432391.1\|453801_455274_-	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_044409272.1\|455637_457173_+	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	1.1e-19	27.3
WP_172432392.1\|457264_457855_-	transcriptional regulator BetI	NA	NA	NA	NA
WP_044409239.1\|458072_458930_-	glycine betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_074967283.1\|459051_459996_-\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_074967285.1\|460031_460928_-	proline/glycine betaine ABC transporter permease	NA	NA	NA	NA
WP_172432393.1\|460929_462126_-	glycine betaine/L-proline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	5.2e-30	38.7
WP_107329260.1\|462795_463734_-\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_074967287.1\|464001_465378_+	L-serine ammonia-lyase	NA	NA	NA	NA
WP_044409222.1\|465796_466891_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_044409219.1\|467715_467961_-	hypothetical protein	NA	NA	NA	NA
WP_044409216.1\|467986_468766_-	electron transfer flavoprotein subunit beta	NA	NA	NA	NA
WP_172432394.1\|468755_469988_-	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
WP_172432395.1\|470025_471984_-	dimethylglycine demethylation protein DgcB	NA	NA	NA	NA
WP_044409207.1\|472076_474137_-	dimethylglycine demethylation protein DgcA	NA	NA	NA	NA
WP_074967296.1\|474152_474683_-	hydrocarbon binding protein	NA	NA	NA	NA
WP_044409203.1\|474890_475868_-	membrane dipeptidase	NA	NA	NA	NA
WP_044409202.1\|476322_476805_+	formate dehydrogenase subunit gamma	NA	NA	NA	NA
WP_172432396.1\|476798_478355_+	formate dehydrogenase	NA	NA	NA	NA
WP_172432397.1\|478351_481228_+	formate dehydrogenase subunit alpha	NA	NA	NA	NA
WP_044409197.1\|481224_481446_+	formate dehydrogenase subunit delta	NA	NA	NA	NA
WP_172432398.1\|481977_482934_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_044409191.1\|483189_484125_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_044409188.1\|484197_485085_+	3-keto-5-aminohexanoate cleavage protein	NA	NA	NA	NA
WP_172432399.1\|485164_486130_+	L-carnitine dehydrogenase	NA	NA	NA	NA
WP_172432400.1\|486164_486644_+	thioesterase family protein	NA	NA	NA	NA
WP_044409178.1\|486684_487317_-	response regulator transcription factor	NA	NA	NA	NA
WP_172435029.1\|487881_491400_+	transporter substrate-binding domain-containing protein	A0A1V0SGX0	Hokovirus	1.9e-40	32.7
WP_074967311.1\|491393_492584_-	EAL domain-containing response regulator	NA	NA	NA	NA
WP_160481645.1\|492748_493381_+	response regulator	NA	NA	NA	NA
WP_172432401.1\|493668_494196_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_172432402.1\|494250_494982_+	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_172432403.1\|495055_497710_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_172432404.1\|497790_498102_-	hypothetical protein	NA	NA	NA	NA
WP_044409161.1\|498652_499945_-	glycine-betaine demethylase subunit GbcA	NA	NA	NA	NA
WP_044409158.1\|500305_501406_+	glycine-betaine demethylase subunit GbcB	NA	NA	NA	NA
WP_044409155.1\|502124_503168_-	low specificity L-threonine aldolase	NA	NA	NA	NA
WP_044409151.1\|503383_503683_+	hypothetical protein	NA	NA	NA	NA
WP_107331324.1\|503867_504173_-	NIPSNAP family protein	NA	NA	NA	NA
WP_172432405.1\|504900_506154_+	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	2.6e-104	54.8
WP_044409143.1\|506169_507420_+	sarcosine oxidase subunit beta family protein	NA	NA	NA	NA
WP_044409140.1\|507431_507758_+	sarcosine oxidase subunit delta	NA	NA	NA	NA
WP_172432406.1\|507754_510775_+	sarcosine oxidase subunit alpha	NA	NA	NA	NA
WP_044409134.1\|510767_511397_+	sarcosine oxidase subunit gamma	NA	NA	NA	NA
WP_172432407.1\|511507_512365_+	formyltetrahydrofolate deformylase	NA	NA	NA	NA
WP_172432408.1\|512552_513752_+	formaldehyde dehydrogenase, glutathione-independent	A0A2K9L7I1	Tupanvirus	2.9e-12	29.3
WP_152644507.1\|513880_515926_-\|holin	choline BCCT transporter BetT	A0A2I7QNT1	Vibrio_phage	1.0e-20	26.9

DBSCAN-SWA_2

1182797 : 1190798

Acanthamoeba_polyphaga_mimivirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044403764.1\|1182797_1183562_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	1.2e-14	29.4
WP_172432738.1\|1183631_1185344_+	GMC family oxidoreductase	A0A1V0S9M4	Catovirus	1.0e-39	27.0
WP_172432739.1\|1185400_1186147_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_172432740.1\|1186174_1187425_+	acyltransferase	B5WZU0	Pseudomonas_phage	4.4e-11	26.5
WP_172432741.1\|1187492_1187783_-	metal-binding protein	NA	NA	NA	NA
WP_172432742.1\|1187772_1188429_-	2OG-Fe(II) oxygenase	NA	NA	NA	NA
WP_172432743.1\|1188404_1189526_-	bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	5.1e-19	53.3
WP_107331219.1\|1189608_1190244_-	DNA-3-methyladenine glycosylase 2 family protein	S4VP92	Pandoravirus	5.1e-08	29.3
WP_172432744.1\|1190246_1190798_-	methylated-DNA--[protein]-cysteine S-methyltransferase	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	4.3e-19	48.1

DBSCAN-SWA_3

2507113 : 2564563

Pseudomonas_phage(37.78%)

terminase,portal,tRNA,protease,integrase,tail,holin

attL 2491726:2491743|attR 2533716:2533733

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2491726:2491743	attL	NA	NA	NA	NA
WP_074972570.1\|2507113_2508229_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_044406298.1\|2508290_2508737_-	NUDIX hydrolase	NA	NA	NA	NA
WP_172433314.1\|2508832_2511061_-	NADP-dependent isocitrate dehydrogenase	NA	NA	NA	NA
WP_044406307.1\|2511426_2512683_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	1.4e-17	81.5
WP_074972708.1\|2512751_2513021_-	cold shock domain-containing protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	4.1e-15	58.2
WP_044406310.1\|2513248_2513611_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	2.5e-12	44.4
WP_172433315.1\|2513639_2515910_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	2.6e-163	42.6
WP_002553999.1\|2515963_2516182_-	translation initiation factor IF-1	NA	NA	NA	NA
WP_044406323.1\|2516281_2516989_-	arginyltransferase	NA	NA	NA	NA
WP_172435074.1\|2517042_2517726_-\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_172433316.1\|2517762_2518716_-	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	2.9e-63	43.9
WP_139233688.1\|2518916_2521346_+	DNA translocase FtsK	G1D482	Mycobacterium_virus	3.3e-87	51.1
WP_074972582.1\|2521375_2522002_+	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_172433317.1\|2522020_2523343_+	replication-associated recombination protein A	G3MBE0	Bacillus_virus	6.8e-79	38.3
WP_044406340.1\|2523339_2523720_+	fluoride efflux transporter CrcB	A0A2H4J148	uncultured_Caudovirales_phage	6.1e-09	42.2
WP_172433318.1\|2523736_2525017_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	4.7e-101	54.5
WP_172433319.1\|2525115_2526507_+	uroporphyrinogen-III C-methyltransferase	NA	NA	NA	NA
WP_172433320.1\|2526494_2527496_-	glutathione S-transferase family protein	NA	NA	NA	NA
WP_172433321.1\|2527570_2528566_-	glycosyl transferase family protein	A0A2H4JBY5	uncultured_Caudovirales_phage	6.8e-132	70.9
WP_069564794.1\|2528562_2528898_-	TusE/DsrC/DsvC family sulfur relay protein	A0A2H4J8B6	uncultured_Caudovirales_phage	3.5e-40	72.1
WP_160481811.1\|2528894_2529197_-	sulfurtransferase complex subunit TusB	A0A2H4JG28	uncultured_Caudovirales_phage	3.4e-26	62.0
WP_172433322.1\|2529196_2529556_-	sulfurtransferase complex subunit TusC	A0A2H4J8C0	uncultured_Caudovirales_phage	9.8e-33	60.8
WP_172433323.1\|2529555_2529948_-	sulfurtransferase complex subunit TusD	A0A2H4JA39	uncultured_Caudovirales_phage	4.3e-50	76.7
WP_044406370.1\|2530051_2530720_-	Bax inhibitor-1/YccA family protein	A0A2H4JFM9	uncultured_Caudovirales_phage	4.7e-97	84.8
WP_069561063.1\|2531060_2532110_-\|integrase	tyrosine-type recombinase/integrase	A0A2H4JDJ8	uncultured_Caudovirales_phage	2.0e-102	54.9
WP_069561062.1\|2532111_2532354_-	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_172433324.1\|2532405_2533170_-	hypothetical protein	Q5QF32	Pseudomonas_virus	1.4e-89	66.5
WP_172433325.1\|2533159_2533492_-	hypothetical protein	NA	NA	NA	NA
WP_172433326.1\|2533488_2534106_-	hypothetical protein	A0A0U1SZL2	Pseudomonas_phage	1.9e-63	59.7
2533716:2533733	attR	NA	NA	NA	NA
WP_172433327.1\|2534098_2534446_-	DUF4406 domain-containing protein	A0A2K8I958	Pseudomonas_phage	1.6e-27	54.8
WP_172433328.1\|2534501_2535524_-	DNA cytosine methyltransferase	Q6J1P4	Burkholderia_virus	2.8e-104	60.5
WP_172433329.1\|2535542_2535749_-	hypothetical protein	A0A1B0Z069	Pseudomonas_phage	8.4e-13	61.3
WP_172433330.1\|2536014_2536329_-	hypothetical protein	A0A2H4JAQ1	uncultured_Caudovirales_phage	3.5e-18	52.4
WP_172433331.1\|2536288_2536696_-	hypothetical protein	NA	NA	NA	NA
WP_172433332.1\|2536698_2536860_-	hypothetical protein	NA	NA	NA	NA
WP_165676937.1\|2537073_2537250_-	carbon storage regulator	NA	NA	NA	NA
WP_172433333.1\|2537337_2537889_-	hypothetical protein	A0A059VFZ8	Pseudomonas_phage	1.9e-27	42.1
WP_172433334.1\|2538539_2538854_+	DUF1654 domain-containing protein	A0A0S2SYC9	Pseudomonas_phage	6.4e-28	60.6
WP_172433335.1\|2538855_2539380_-	hypothetical protein	NA	NA	NA	NA
WP_172433336.1\|2539445_2540114_-	SOS response-associated peptidase	A0A2H4J991	uncultured_Caudovirales_phage	4.2e-69	58.0
WP_172433337.1\|2540217_2540436_+	hypothetical protein	NA	NA	NA	NA
WP_172433338.1\|2540477_2541482_-	hypothetical protein	A0A0R6PIZ6	Moraxella_phage	1.8e-39	32.6
WP_172433339.1\|2541666_2542500_-	S24 family peptidase	H2BD63	Pseudomonas_phage	2.4e-50	45.4
WP_172433340.1\|2542616_2542868_+	hypothetical protein	NA	NA	NA	NA
WP_172433341.1\|2542902_2543511_+	hypothetical protein	NA	NA	NA	NA
WP_172433342.1\|2543507_2544386_+	helix-turn-helix domain-containing protein	A0A1B0YZZ0	Pseudomonas_phage	2.1e-44	48.4
WP_172433343.1\|2544372_2545152_+	hypothetical protein	A0A1B0VMD9	Pseudomonas_phage	1.8e-55	48.2
WP_172433344.1\|2545144_2545357_+	hypothetical protein	NA	NA	NA	NA
WP_172435075.1\|2545356_2545713_+	recombinase	NA	NA	NA	NA
WP_172433345.1\|2545721_2546012_+	hypothetical protein	NA	NA	NA	NA
WP_160480320.1\|2546001_2546343_+	DUF1064 domain-containing protein	T1SA23	Salmonella_phage	8.4e-42	74.3
WP_172433346.1\|2546342_2546657_+	hypothetical protein	NA	NA	NA	NA
WP_172433347.1\|2546670_2547003_+	antitermination protein Q	A0A2D1GNB4	Pseudomonas_phage	9.4e-30	61.1
WP_160482062.1\|2547196_2547586_+	hypothetical protein	H2BD73	Pseudomonas_phage	3.4e-31	55.8
WP_172433348.1\|2547578_2547920_+\|holin	phage holin family protein	A0A0U4J8T9	Pseudomonas_phage	6.1e-16	50.0
WP_172433349.1\|2547921_2548710_+	hypothetical protein	A0A1W6JTE1	Pseudomonas_phage	1.3e-61	51.9
WP_172433350.1\|2548852_2549398_+\|terminase	terminase small subunit	A0A1B0Z033	Pseudomonas_phage	2.4e-70	73.5
WP_172433351.1\|2549369_2551319_+\|terminase	phage terminase large subunit family protein	A0A1B0Z2K0	Pseudomonas_phage	5.9e-273	70.6
WP_172433352.1\|2551318_2551522_+	hypothetical protein	B7SYD5	Stenotrophomonas_phage	3.7e-05	45.8
WP_172433353.1\|2551523_2553032_+\|portal	phage portal protein	Q75QM9	Wolbachia_phage	2.6e-74	36.2
WP_172433354.1\|2553039_2554989_+	hypothetical protein	A0A2I7QRU0	Vibrio_phage	7.6e-87	33.3
WP_172433355.1\|2555063_2555417_+	DUF2190 family protein	NA	NA	NA	NA
WP_172433356.1\|2555420_2555738_+	hypothetical protein	NA	NA	NA	NA
WP_172433357.1\|2555734_2556205_+	hypothetical protein	A0A1W6JT75	Pseudomonas_phage	9.6e-28	44.1
WP_172433358.1\|2556201_2556375_+	hypothetical protein	NA	NA	NA	NA
WP_172433359.1\|2556382_2557159_+	hypothetical protein	A0A1W6JT83	Pseudomonas_phage	3.7e-85	65.6
WP_172433360.1\|2557204_2557699_-	Arc family DNA-binding protein	A0A0H5AWD9	Pseudomonas_phage	4.7e-09	74.4
WP_172433361.1\|2557763_2557910_+	Arc family DNA-binding protein	NA	NA	NA	NA
WP_172433362.1\|2557978_2558884_+	Bro-N domain-containing protein	A0A2H4JG39	uncultured_Caudovirales_phage	7.9e-71	70.1
WP_172433363.1\|2558880_2559615_+	Rha family transcriptional regulator	A0A2H4IZE1	uncultured_Caudovirales_phage	1.6e-42	59.1
WP_172432196.1\|2559706_2560507_+	hypothetical protein	NA	NA	NA	NA
WP_172433364.1\|2560561_2561029_+	hypothetical protein	NA	NA	NA	NA
WP_160480340.1\|2561064_2561202_+	hypothetical protein	NA	NA	NA	NA
WP_172433365.1\|2561212_2564563_+\|tail	phage tail tape measure protein	Q75QK7	Wolbachia_phage	3.4e-50	30.6

DBSCAN-SWA_4

2569755 : 2575235

Pseudomonas_phage(50.0%)

head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_172433370.1\|2569755_2570346_+	hypothetical protein	A0A1B0Z051	Pseudomonas_phage	3.6e-40	44.0
WP_172433371.1\|2570335_2570662_+	hypothetical protein	NA	NA	NA	NA
WP_172433372.1\|2570671_2571394_+\|head	head decoration protein	A0A2D1ADT9	Rhodococcus_phage	6.1e-50	48.5
WP_172433373.1\|2571393_2572284_+	hypothetical protein	NA	NA	NA	NA
WP_172433374.1\|2572271_2572727_+	hypothetical protein	NA	NA	NA	NA
WP_172433375.1\|2572769_2573411_+	glycoside hydrolase family 19 protein	A0A125RNP1	Pseudomonas_phage	1.7e-67	63.4
WP_172433376.1\|2573407_2573773_+	hypothetical protein	J7HXL1	Pseudomonas_phage	3.6e-14	45.6
WP_172433377.1\|2573769_2574036_+	hypothetical protein	H2BDD7	Pseudomonas_virus	2.4e-20	63.1
WP_172433378.1\|2574110_2574551_+	PAS domain-containing protein	NA	NA	NA	NA
WP_172433379.1\|2575022_2575235_+	cold shock domain-containing protein	Q9AZD3	Lactococcus_phage	6.6e-13	50.0

DBSCAN-SWA_5

3303978 : 3360391

Ralstonia_phage(40.0%)

transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_074971463.1\|3303978_3305313_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_172433787.1\|3305329_3305809_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_172433788.1\|3305891_3307637_-	type VI secretion system-associated FHA domain protein TagH	NA	NA	NA	NA
WP_172435095.1\|3308040_3309072_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_044407521.1\|3309158_3309674_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_107329446.1\|3309686_3311183_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_044407523.1\|3311257_3311746_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_044407525.1\|3311818_3312250_+	hypothetical protein	NA	NA	NA	NA
WP_172433789.1\|3312246_3312675_+	hypothetical protein	NA	NA	NA	NA
WP_074971468.1\|3312729_3313515_+	virulence protein SciE type	NA	NA	NA	NA
WP_074971469.1\|3313517_3314033_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_142008862.1\|3314029_3315889_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_074971471.1\|3315852_3316893_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_044407541.1\|3316895_3319592_+	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	2.3e-86	32.0
WP_172433790.1\|3319694_3321632_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	2.1e-44	26.4
WP_044407547.1\|3321906_3322299_+	VOC family protein	NA	NA	NA	NA
WP_044407550.1\|3322356_3322914_+	gluconate 2-dehydrogenase subunit 3 family protein	NA	NA	NA	NA
WP_172433791.1\|3322926_3324495_+	GMC family oxidoreductase	NA	NA	NA	NA
WP_069566640.1\|3324610_3324895_-	hypothetical protein	NA	NA	NA	NA
WP_074971474.1\|3324891_3326187_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_044407562.1\|3326229_3326664_-	DcrB-related protein	NA	NA	NA	NA
WP_172433792.1\|3326931_3328053_+	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_172433793.1\|3328068_3328578_-	hypothetical protein	NA	NA	NA	NA
WP_172433794.1\|3328574_3328859_-	hypothetical protein	NA	NA	NA	NA
WP_172433795.1\|3328855_3329119_-	hypothetical protein	NA	NA	NA	NA
WP_044407571.1\|3329115_3329544_-	GTP pyrophosphokinase	A0A141E1X8	Streptococcus_phage	3.2e-22	38.9
WP_142008836.1\|3329874_3332097_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	6.1e-48	28.3
WP_172433796.1\|3332120_3332567_+	hypothetical protein	NA	NA	NA	NA
WP_172433797.1\|3332580_3333696_+	DUF2169 domain-containing protein	NA	NA	NA	NA
WP_172433798.1\|3333692_3334730_+	hypothetical protein	NA	NA	NA	NA
WP_172433799.1\|3334729_3335893_+	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_172435096.1\|3336138_3336843_+	hypothetical protein	NA	NA	NA	NA
WP_172433800.1\|3336885_3338127_+	TIGR02270 family protein	NA	NA	NA	NA
WP_172435097.1\|3338413_3339118_+	hypothetical protein	NA	NA	NA	NA
WP_172433801.1\|3339307_3340207_+	hypothetical protein	NA	NA	NA	NA
WP_172433802.1\|3340316_3341210_+	hypothetical protein	NA	NA	NA	NA
WP_172433803.1\|3341404_3341848_+	type II 3-dehydroquinate dehydratase	NA	NA	NA	NA
WP_172433804.1\|3341853_3342711_+	shikimate dehydrogenase	NA	NA	NA	NA
WP_069563412.1\|3342759_3343431_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_172433805.1\|3343521_3345432_-	TIM barrel protein	NA	NA	NA	NA
WP_074971489.1\|3346001_3347375_+	MHS family MFS transporter	NA	NA	NA	NA
WP_172433806.1\|3347449_3348412_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_172433807.1\|3348502_3349465_-	peptidylprolyl isomerase	NA	NA	NA	NA
WP_172433808.1\|3349468_3349954_-	YbjN domain-containing protein	NA	NA	NA	NA
WP_172433809.1\|3350005_3350641_-	DNA repair protein	NA	NA	NA	NA
WP_172433810.1\|3350664_3352359_-	putative porin	NA	NA	NA	NA
WP_172433811.1\|3352398_3353124_-	energy transducer TonB	NA	NA	NA	NA
WP_044407744.1\|3353127_3353550_-	biopolymer transporter ExbD	NA	NA	NA	NA
WP_172433812.1\|3353560_3355411_-	DUF2341 domain-containing protein	NA	NA	NA	NA
WP_172433813.1\|3355429_3357133_-	ShlB/FhaC/HecB family hemolysin secretion/activation protein	NA	NA	NA	NA
WP_044407810.1\|3357155_3357755_-\|transposase	transposase	NA	NA	NA	NA
WP_074971811.1\|3358103_3358385_-	hypothetical protein	NA	NA	NA	NA
WP_165673818.1\|3358700_3358844_-	hypothetical protein	NA	NA	NA	NA
WP_172433814.1\|3359100_3359433_-	hypothetical protein	NA	NA	NA	NA
WP_172433815.1\|3359541_3360391_+\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	9.8e-23	45.0

DBSCAN-SWA_6

4526039 : 4546891

Haemophilus_phage(43.48%)

plate,tail,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044411587.1\|4526039_4526366_+	Arc family DNA-binding protein	A0A1Y0SXL4	Pseudomonas_phage	2.2e-15	63.2
WP_044411585.1\|4526465_4527908_-	magnesium transporter	NA	NA	NA	NA
WP_172434378.1\|4528223_4528730_+	DUF4124 domain-containing protein	A0A1B0Z2K9	Pseudomonas_phage	3.0e-11	31.4
WP_172434379.1\|4528838_4529093_-	hypothetical protein	A0A248XCT8	Klebsiella_phage	1.4e-12	59.2
WP_172434380.1\|4529089_4529470_-	hypothetical protein	NA	NA	NA	NA
WP_172434381.1\|4529466_4530108_-	glycoside hydrolase family 19 protein	A0A125RNP1	Pseudomonas_phage	3.0e-64	61.1
WP_172434382.1\|4530098_4530605_-	hypothetical protein	B5TK78	Pseudomonas_phage	4.6e-28	38.6
WP_172434383.1\|4530601_4531975_-	hypothetical protein	B5TK77	Pseudomonas_phage	7.8e-62	41.3
WP_172434384.1\|4532230_4532728_-	DUF4376 domain-containing protein	A0A2H4JF49	uncultured_Caudovirales_phage	1.3e-27	55.2
WP_172434385.1\|4532727_4534992_-\|tail	tail fiber protein	A9DEL7	Yersinia_phage	2.9e-69	37.4
WP_069563013.1\|4534988_4535627_-	DUF2612 domain-containing protein	D0UIH4	Aggregatibacter_phage	1.1e-45	49.5
WP_160481213.1\|4535623_4536769_-\|plate	baseplate J/gp47 family protein	Q7Y5S4	Haemophilus_phage	3.9e-99	51.3
WP_044411559.1\|4536831_4537185_-	hypothetical protein	Q7Y5S5	Haemophilus_phage	2.0e-30	56.6
WP_172434386.1\|4537195_4537837_-	hypothetical protein	D0UIH7	Aggregatibacter_phage	2.7e-41	41.2
WP_069564431.1\|4537829_4538687_-	hypothetical protein	Q7Y5S8	Haemophilus_phage	1.8e-69	48.4
WP_044411556.1\|4538683_4539001_-	hypothetical protein	Q7Y5S9	Haemophilus_phage	1.9e-24	50.5
WP_044411553.1\|4538997_4539759_-	hypothetical protein	Q7Y5T0	Haemophilus_phage	3.7e-29	34.4
WP_172434387.1\|4539768_4541520_-	hypothetical protein	Q7Y5T2	Haemophilus_phage	3.2e-20	30.9
WP_160158626.1\|4541509_4541674_-	hypothetical protein	Q776V6	Haemophilus_phage	1.1e-07	52.4
WP_069563008.1\|4541670_4542078_-	hypothetical protein	Q776V6	Haemophilus_phage	3.0e-22	42.9
WP_044411548.1\|4542080_4542512_-	DUF3277 family protein	Q7Y5T4	Haemophilus_phage	6.1e-37	52.1
WP_172434388.1\|4542574_4544074_-	DUF3383 domain-containing protein	Q7Y5T5	Haemophilus_phage	1.2e-140	53.1
WP_044411543.1\|4544699_4544975_-\|holin	phage holin family protein	H2BD74	Pseudomonas_phage	7.8e-14	49.5
WP_044411540.1\|4544967_4545342_-	hypothetical protein	H2BD73	Pseudomonas_phage	8.7e-24	52.9
WP_044411537.1\|4545502_4546033_-	hypothetical protein	NA	NA	NA	NA
WP_172434389.1\|4546180_4546891_+	helix-turn-helix transcriptional regulator	A0A1B0VRI7	Pseudomonas_phage	6.0e-58	48.6

DBSCAN-SWA_7

4792388 : 4800567

Pseudomonas_phage(87.5%)

integrase,capsid

attL 4792336:4792355|attR 4806553:4806572

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4792336:4792355	attL	NA	NA	NA	NA
WP_172434487.1\|4792388_4793384_-\|integrase	tyrosine-type recombinase/integrase	Q56VN7	Pseudomonas_phage	4.7e-93	51.4
WP_172434488.1\|4793383_4794661_-	hypothetical protein	Q56VN8	Pseudomonas_phage	5.6e-131	54.5
WP_172434489.1\|4794807_4796097_-	hypothetical protein	Q56VN9	Pseudomonas_phage	9.6e-147	64.9
WP_172434490.1\|4796099_4796456_-	DUF2523 domain-containing protein	Q56VP0	Pseudomonas_phage	5.3e-31	56.8
WP_172434491.1\|4796458_4797379_-	hypothetical protein	NA	NA	NA	NA
WP_172434492.1\|4797854_4798076_-\|capsid	major capsid protein	Q56VP2	Pseudomonas_phage	1.1e-07	49.3
WP_069563383.1\|4798084_4798318_-	hypothetical protein	NA	NA	NA	NA
WP_069563382.1\|4798475_4798835_-	hypothetical protein	NA	NA	NA	NA
WP_172434493.1\|4799082_4799295_-	hypothetical protein	NA	NA	NA	NA
WP_172434494.1\|4799298_4799934_-	DNA cytosine methyltransferase	Q6UJ20	Burkholderia_virus	7.8e-65	66.9
WP_172435136.1\|4799937_4800222_-	DUF5447 family protein	Q56VP7	Pseudomonas_phage	2.1e-22	58.0
WP_107331557.1\|4800366_4800567_-	hypothetical protein	Q56VP9	Pseudomonas_phage	2.1e-16	57.1
4806553:4806572	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage