CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP049333	Sphingobacterium sp. DR205 chromosome, complete genome	4 crisprs	c2c10_CAS-V-U3,WYL,cas3,PD-DExK,DEDDh,csa3	2	7	2	0

1. NZ_CP049333

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP049333_1

• CRISPR_ID: NZ_CP049333_1
• CRISPR_location: 1516542-1516971
• CRISPR_type: TypeV-U3
• Repeat_type: NA
• Spacer_info: 6 spacers
• Cas_protein_info: c2c10_CAS-V-U3

Consensus repeat of NZ_CP049333_1

Consensus_repeat	Method
GATGTTGATGACCTCAAAAAGTAGGGTATA	CRISPRCasFinder
NATGTTGATGATCTCAAAATGTAGGGTATACACAAC	CRT

spacers of NZ_CP049333_1

>1.1|1516572|36|NZ_CP049333|CRISPRCasFinder
CACAGCAATATCCTCCTTATACAACAACCCCTTCTC
>1.2|1516638|35|NZ_CP049333|CRISPRCasFinder
TACAACTGGAATGCTTATGATATCAGCACTTGCAA
>1.3|1516703|37|NZ_CP049333|CRISPRCasFinder
CACAACTTAAATAATTGGGATATACAACTTCTTCAAG
>1.4|1516770|36|NZ_CP049333|CRISPRCasFinder
CACAACACGAGCATTCGATATATTTAATCTGAGTTT
>1.5|1516836|35|NZ_CP049333|CRISPRCasFinder
CACAACTGGAATGCTTATGATATCAGCACTTGCAA
>1.6|1516578|31|NZ_CP049333|CRT
AATATCCTCCTTATACAACAACCCCTTCTCC
>1.7|1516644|30|NZ_CP049333|CRT
TGGAATGCTTATGATATCAGCACTTGCAAG
>1.8|1516709|32|NZ_CP049333|CRT
TTAAATAATTGGGATATACAACTTCTTCAAGG
>1.9|1516776|31|NZ_CP049333|CRT
ACGAGCATTCGATATATTTAATCTGAGTTTG
>1.10|1516842|30|NZ_CP049333|CRT
TGGAATGCTTATGATATCAGCACTTGCAAG
>1.11|1516907|30|NZ_CP049333|CRT
AAATATCATTCACATTATCTTTATTGGATT

CRISPR arrays and Neighbor proteins around NZ_CP049333_1

CRISPR arrays

The CRISPR arrays of NZ_CP049333_1

>merge|NZ_CP049333|1|1516542-1516971|CRISPRCasFinder,CRT
GATGTTGATGATCTCGAAATGTAGGGTATACACAGCAATATCCTCCTTATACAACAACCCCTTCTCCATGTTGATGACCTCAAAAAGTGGGGTATATACAACTGGAATGCTTATGATATCAGCACTTGCAAGATGTTGATGATCCCAAAATGTAGGGTATACACAACTTAAATAATTGGGATATACAACTTCTTCAAGGATGTTGATGATCTCAAAATGTAGGGTATACACAACACGAGCATTCGATATATTTAATCTGAGTTTGATGTTGATGACCTCAAAAAGTAGGGTATACACAACTGGAATGCTTATGATATCAGCACTTGCAAGATGTTGATGATCTCAAAATGTTGGGTATACACAACAAATATCATTCACATTATCTTTATTGGATTGATGTTAAAGATCTCAAATGTAGTGTATATGCAAC

>NZ_CP049333|1|1|1516542-1516901|CRISPRCasFinder
GATGTTGATGATCTCGAAATGTAGGGTATA	CACAGCAATATCCTCCTTATACAACAACCCCTTCTC
CATGTTGATGACCTCAAAAAGTGGGGTATA	TACAACTGGAATGCTTATGATATCAGCACTTGCAA
GATGTTGATGATCCCAAAATGTAGGGTATA	CACAACTTAAATAATTGGGATATACAACTTCTTCAAG
GATGTTGATGATCTCAAAATGTAGGGTATA	CACAACACGAGCATTCGATATATTTAATCTGAGTTT
GATGTTGATGACCTCAAAAAGTAGGGTATA	CACAACTGGAATGCTTATGATATCAGCACTTGCAA
GATGTTGATGATCTCAAAATGTTGGGTATAC

>NZ_CP049333|1|1|1516543-1516971|CRT
ATGTTGATGATCTCGAAATGTAGGGTATACACAGC	AATATCCTCCTTATACAACAACCCCTTCTCC
ATGTTGATGACCTCAAAAAGTGGGGTATATACAAC	TGGAATGCTTATGATATCAGCACTTGCAAG
ATGTTGATGATCCCAAAATGTAGGGTATACACAAC	TTAAATAATTGGGATATACAACTTCTTCAAGG
ATGTTGATGATCTCAAAATGTAGGGTATACACAAC	ACGAGCATTCGATATATTTAATCTGAGTTTG
ATGTTGATGACCTCAAAAAGTAGGGTATACACAAC	TGGAATGCTTATGATATCAGCACTTGCAAG
ATGTTGATGATCTCAAAATGTTGGGTATACACAAC	AAATATCATTCACATTATCTTTATTGGATT
GATGTTAAAGATCTCAAATGTAGTGTATATGCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049333.1|WP_165305843.1|1510531_1512076_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl|CDD|185760
NZ_CP049333.1|WP_165305841.1|1505011_1507147_+|DUF5110-domain-containing-protein	unknown	unknown	gnl|CDD|376446
NZ_CP049333.1|WP_165305845.1|1514734_1515238_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NZ_CP049333.1|WP_165305848.1|1519391_1520486_+|hypothetical-protein	c2c10_CAS-V-U3	-	gnl|CDD|273793
NZ_CP049333.1|WP_165305844.1|1512894_1514358_+|alginate-lyase	unknown	unknown	gnl|CDD|271210
NZ_CP049333.1|WP_108637014.1|1512100_1512868_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP049333.1|WP_165305849.1|1520487_1521057_-|hypothetical-protein	unknown	unknown	gnl|CDD|372659
NZ_CP049333.1|WP_165305838.1|1501827_1502586_+|LamB/YcsF-family-protein	unknown	unknown	gnl|CDD|377121
NZ_CP049333.1|WP_165305842.1|1507420_1510519_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|274948
NZ_CP049333.1|WP_165305840.1|1503881_1505006_+|glycosyl-hydrolase	unknown	unknown	gnl|CDD|369381
NZ_CP049333.1|WP_165305851.1|1526526_1528464_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl|CDD|369630
NZ_CP049333.1|WP_108632869.1|1521278_1521584_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP049333.1|WP_165305850.1|1523327_1526501_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|274948
NZ_CP049333.1|WP_165305852.1|1528478_1529705_+|DUF4959-domain-containing-protein	unknown	unknown	gnl|CDD|379822
NZ_CP049333.1|WP_165305837.1|1500878_1501835_+|biotin-dependent-carboxyltransferase-family-protein	unknown	unknown	gnl|CDD|224895
NZ_CP049333.1|WP_165305847.1|1518562_1519375_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NZ_CP049333.1|WP_165305854.1|1531007_1533035_+|alpha-galactosidase	unknown	unknown	gnl|CDD|269892
NZ_CP049333.1|WP_165305855.1|1533044_1534085_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|153418
NZ_CP049333.1|WP_165305839.1|1502582_1503752_+|divalent-metal-cation-transporter	unknown	unknown	gnl|CDD|224826
NZ_CP049333.1|WP_165305853.1|1529729_1530929_+|hypothetical-protein	unknown	unknown	gnl|CDD|379841

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP049333.1|WP_165305848.1|1519391_1520486_+|hypothetical-protein	c2c10_CAS-V-U3	-	9.9e-54	177.5	12.5

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP049333.1|WP_165305843.1|1510531_1512076_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl|CDD|185760	cd08977, SusD, starch binding outer membrane protein SusD. SusD-like proteins from Bacteroidetes, members of the human distal gut microbiota, are part of the starch utilization system (Sus). Sus is one of the large clusters of glycosyl hydrolases, called polysaccharide utilization loci (PULs), which play an important role in polysaccharide recognition and uptake, and it is needed for growth on amylose, amylopectin, pullulan, and maltooligosaccharides. SusD, together with SusC, a predicted beta-barrel porin, forms the minimum outer-membrane starch-binding complex. The adult human distal gut microbiota is essential for digestion of a large variety of dietary polysaccharides, for which humans lack the necessary glycosyl hydrolases.	1.40785e-34
NZ_CP049333.1|WP_165305841.1|1505011_1507147_+|DUF5110-domain-containing-protein	gnl|CDD|376446	pfam01055, Glyco_hydro_31, Glycosyl hydrolases family 31. Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases.	3.59352e-89
NZ_CP049333.1|WP_165305845.1|1514734_1515238_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.58351e-06
NZ_CP049333.1|WP_165305848.1|1519391_1520486_+|hypothetical-protein	gnl|CDD|273793	TIGR01766, Putative_transposase_MJ0751, transposase, IS605 OrfB family, central region. This model represents a region of a sequence similarity between a family of putative transposases of Thermoanaerobacter tengcongensis, smaller related proteins from Bacillus anthracis, putative transposes described by pfam01385, and other proteins. [Mobile and extrachromosomal element functions, Transposon functions].	0.00203156
NZ_CP049333.1|WP_165305844.1|1512894_1514358_+|alginate-lyase	gnl|CDD|271210	cd14251, PL-6, Polysaccharide Lyase Family 6. Polysaccharide Lyase Family 6 is a family of beta-helical polysaccharide lyases. Members include alginate lyase (EC 4.2.2.3) and chondroitinase B (EC 4.2.2.19). Chondroitinase B is an enzyme that only cleaves the beta-(1,4)-linkage of dermatan sulfate (DS), leading to 4,5-unsaturated dermatan sulfate disaccharides as the product. DS is a highly sulfated, unbranched polysaccharide belonging to a family of glycosaminoglycans (GAGs) composed of alternating hexosamine (gluco- or galactosamine) and uronic acid (D-glucuronic or L-iduronic acid) moieties. DS contains alternating 1,4-beta-D-galactosamine (GalNac) and 1,3-alpha-L-iduronic acid units. The related chondroitin sulfate (CS) contains alternating GalNac and 1,3-beta-D-glucuronic acid units. Alginate lyases (known as either mannuronate (EC 4.2.2.3) or guluronate lyases (EC 4.2.2.11) catalyze the degradation of alginate, a copolymer of alpha-L-guluronate and its C5 epimer beta-D-mannuronate.	1.88279e-154
NZ_CP049333.1|WP_165305837.1|1500878_1501835_+|biotin-dependent-carboxyltransferase-family-protein	gnl|CDD|224895	COG1984, DUR1, Allophanate hydrolase subunit 2 [Amino acid transport and metabolism].	1.15976e-131
NZ_CP049333.1|WP_165305849.1|1520487_1521057_-|hypothetical-protein	gnl|CDD|372659	pfam13644, DKNYY, DKNYY family. This family represents a group of proteins found enriched in fusobacteria. These proteins contain many repeats of a DKNXXYY motif. The repeats are spaced at about 35 amino acid residues intervals. These proteins are likely to be associated with the membrane. The specific function of these proteins is unknown.	1.69329e-19
NZ_CP049333.1|WP_165305838.1|1501827_1502586_+|LamB/YcsF-family-protein	gnl|CDD|377121	pfam03746, LamB_YcsF, LamB/YcsF family. This family includes LamB. The lam locus of Aspergillus nidulans consists of two divergently transcribed genes, lamA and lamB, involved in the utilisation of lactams such as 2-pyrrolidinone. Both genes are under the control of the positive regulatory gene amdR and are subject to carbon and nitrogen metabolite repression. The exact molecular function of the proteins in this family is unknown.	3.51543e-148
NZ_CP049333.1|WP_165305842.1|1507420_1510519_+|TonB-dependent-receptor	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0
NZ_CP049333.1|WP_165305840.1|1503881_1505006_+|glycosyl-hydrolase	gnl|CDD|369381	pfam07470, Glyco_hydro_88, Glycosyl Hydrolase Family 88. Unsaturated glucuronyl hydrolase catalyzes the hydrolytic release of unsaturated glucuronic acids from oligosaccharides (EC:3.2.1.-) produced by the reactions of polysaccharide lyases.	7.73875e-50
NZ_CP049333.1|WP_165305851.1|1526526_1528464_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl|CDD|369630	pfam07980, SusD_RagB, SusD family. This domain is found in bacterial cell surface proteins such SusD and SusD-like proteins, as as well RagB, outer membrane surface receptor antigen. Bacteroidetes, one of the two dominant bacterial phyla in the human gut, are Gram-negative saccharolytic microorganisms that utilize a diverse array of glycans. Hence, they express starch-utilization system (Sus) for glycan uptake. SusD has 551 amino acids, and is almost entirely alpha-helical, with 22 alpha-helices, eight of which form 4 tetra-trico peptide repeats (TPRs: helix-turn-helix motifs involved in protein-protein interactions). The four TPRs pack together to create a right-handed super-helix. This is predicted to mediate the formation of SusD and SusC porin complex at the cell surface. The interaction between SusC and TPR1/TPR2 region of SusD is predicted to be of functional importance since it allows SusD to be in position for oligosaccharide capture from other Sus lipoproteins and delivery of these glycans to the SusC porin. The non-TPR containing portion of SusD is where starch binding occurs. The binding site is a shallow surface cavity located on top of TPR1. SusD homologs such as SusD-like proteins have a critical role in carbohydrate acquisition. Both SusD and its homologs, contain about 15-20 residues at the N-terminus that might be a flexible linker region, anchoring the protein to the membrane and the glycan-binding domain. Other homologs to SusD have been examined in Porphyromonas gingivalis such as RagB, an immunodominant outer-membrane surface receptor antigen. Structural characterization of RagB shows substantial similarity with Bacteroides thetaiotaomicron SusD (i.e alpha-helices and TPR regions). Based on this structural similarity, functional studies suggest that, RagB binding of glycans occurs at pockets on the molecular surface that are distinct from those of SusD.	2.50181e-46
NZ_CP049333.1|WP_165305850.1|1523327_1526501_+|TonB-dependent-receptor	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0
NZ_CP049333.1|WP_165305852.1|1528478_1529705_+|DUF4959-domain-containing-protein	gnl|CDD|379822	pfam16323, DUF4959, Domain of unknown function (DUF4959). This family consists of uncharacterized proteins around 400 residues in length and is mainly found in various Bacteroides, Pedobacter and Parabacteroides species. Several proteins are annotated as Galactose-binding like proteins, but the specific function of this protein is unknown.	4.21279e-38
NZ_CP049333.1|WP_165305847.1|1518562_1519375_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	0.00620894
NZ_CP049333.1|WP_165305854.1|1531007_1533035_+|alpha-galactosidase	gnl|CDD|269892	cd14791, GH36, glycosyl hydrolase family 36 (GH36). GH36 enzymes occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-galactosidase, alpha-N-acetylgalactosaminidase, stachyose synthase, and raffinose synthase. All GH36 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH36 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.	2.00903e-10
NZ_CP049333.1|WP_165305855.1|1533044_1534085_+|GntR-family-transcriptional-regulator	gnl|CDD|153418	cd07377, WHTH_GntR, Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators. This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.	3.56462e-10
NZ_CP049333.1|WP_165305839.1|1502582_1503752_+|divalent-metal-cation-transporter	gnl|CDD|224826	COG1914, MntH, Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism].	1.05695e-61
NZ_CP049333.1|WP_165305853.1|1529729_1530929_+|hypothetical-protein	gnl|CDD|379841	pfam16389, DUF4998, Domain of unknown function. This family around 200 residues locates in the N-terminal of some uncharacterized proteins in various Bacteroides and Parabacteroides species. The function of this family remains unknown.	5.42893e-48

Protein sequences

>NZ_CP049333.1|WP_165305845.1|1514734_1515238_-|helix-turn-helix-transcriptional-regulator
MGDINEQILEEIGEQLRIQREKIYYTLKDVANMTGLTTNTIAAVERGKGASLNNFILICRALNIQPHTIFKKEIDLTPLYNIPPESKRRIEMTKELDDLVYNSNFFEIPRRVSDIIQQLNANKEQSNKFSVYLSSYCQEGTLEYEKHGNYKEYRKKHSPKPVKKYSK
>NZ_CP049333.1|WP_165305844.1|1512894_1514358_+|alginate-lyase
MNAKKMVFASLSLLLVIGSSCEKPVMINMQLNGVACVQCHTIQSAADLQALSLHPGDTVIMKSGQWTDQELTFAAQGTSQQPIVLMAEQPGTVILKGMSSVSITGKWLVVSGLVFQNGYTSGKNVIDFTSSSSNCRLTNSAIVDYNPPTATTDYRWVSINGSNHRVDHCYLKGKSHQGPTMVVWGTNKTMKHRIDHNFFGKRAELANNGGETIRIGTSDWSMTNAYTTIEDNIFQRCNGEMEIISNKMGADTIRNNFFHESQGTLCLRHGNGSAVYGNYFVGNGNSAAGGIRIIGEDHIVYNNYFQHMSGTGQKAPLVLMDGVPNSPLSGYYQVKRVKVVANTMIKCKQSFDIGSGKGGSSRTLPPTDGHIANNVVSQVATSTMLTFTDQPINFTYQGNIVYDVPTSQQLPAGFTRQNPQYTLTAEGIYEPTGNSPVLGAFVGNYPFAAAADAGAPKLDNKHRDLLKAQNIGPGFMTGLGNSLVINP
>NZ_CP049333.1|WP_108637014.1|1512100_1512868_+|hypothetical-protein
MKRNFNIKWIQVGVMLLTLLTTGCSLFDMELQENYDYEHKTLDPNIGISARKFLENRSYGTPENPTDTAFKWMRMGLEYAGIDLNELEKADRTFIFLHNDAIKIWDVKTKKVTGGLFLDFPIVTGVDGTGKPLTKPAAKWEDYSKEDVRNYFLYLILQGKYNFADLSIDNVKAKTLLPANTVASKGSLLGYLNEGKGFDQEGAMYLKLVNNSDLAPIQINNKTTNRSGGYGVTNGVVHVYGVKGNTTVYPFISLQ
>NZ_CP049333.1|WP_165305843.1|1510531_1512076_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MYKIKILAALLFLGTLGGCNKFLDEKPLADGTLDQHYKNMYDVQAAMAGMYSAFQLEMVGKEQYTEKYLYWGEYRSDNFDRFISYTKDYVDEIVLNSITPSNDFSDWSGLYTTIGRANNNIKYIPQAAQLDSRITMAMQNDYLAQSYALRAMSYFYIVRVWGDAPIWLEPYEDVQQPAERAREPKEKLLKDVIIPDLEKAYSLITKDARSPLWTIGEAGICAIMADVYMWQGDHENAIKWIEKLFLAKSPTNVTYAGLNETNLQDAATWKTIFTNPSSSKETIWSIHWDYLKNGCACMQTSWTSNNKQVIVDEGIWTSWFLPQTTSTPSPDIRPKQTLDVYFGMPSNKRDRFIKWYPTEANPTKADPWPATNQLLPVYLTMYRLSDIYLLYAEALNARGDREKAIKYLNFVRKRAQLPAYDVSAPELATPYALETAILNERQLELFGEGKRWFDLVRTNRVKVVMDPILKRRQEDAGNLEMPGFLDPKNRAYWPLNRNVLNSNSLLVQNPGYTD
>NZ_CP049333.1|WP_165305842.1|1507420_1510519_+|TonB-dependent-receptor
MMKSITKMGCFVLCLFLLMGSMGLPLFAQQNIRISGKVSNSKGDALQGVSVRIKGKSQGTSTDAAGKYQLEAAPTNILVFSQVGMKEEERAIGSQRQIDVQLVESDNALDEIVVTGYGSVAKKRDLTGAISSVSAKKIQERQPINLFDALQGQAAGVLIVNDGGGAPGATGSIQVRGTSTLNGGNGPLYLVDGVINPDGANINPTDIENIEVLKDAASASIYGSRAANGVILITTKRGAEGKPLINVNYNHLFGRLAHYIPVSNSAEVREFRNIQGQNSNIDSLNPSFNADNDLQKLLLGNLAQKKEIKLSIGGGQKNLRYYSSLNYLDDKSIILNSYAKRLQSRINVEYQASSKLRYSNNISFAWQKGNSIPIANTVRVVMDRPAYSLIYYPDGSLTSYVGSKRNPVANALYEQNIDETYSGQFNNQLDYQLTNDLKLTTLFNARLDNLQNTGFSPRFLSANKDQNNGSNEFTKTFSWEFQAFANYNKTFAQDHNVYALLGFSADRRRFDRFHSEYLNSVNEEVLVTFPDYLTSSKTYTSATANATASLFSRVGYNYKSRYLLQASYRRDGSSRFGPSNKWGNFFSGSAAWRFSDENFMKWAKPALQDAKLRYSFGQLGNDKIGDYESYAKVAFGGNYNGVGGASMTPTLGNYLIKWEMTTQNNVGLDLTFLNGRLGFTADYYVKTTTDLLYPRELPKETGYTKLQVNVGSIRTRGMEFVVNARPIVQSNFTWEINGNISFERGKVVKLADGIPFFPGNKWYLEEGGRIGNFYGWRNLGVYAWDESNAYNDNWDKLTLVLDDQGKPLYRDGKPVYTSDGQNYEGPVHHLYAPDGKLKGGDAEWFNNKRDSLINDDDRMILGNPTPDFYFGFMQTFTYKRFSLNVLFNGAIGGEVYNALLQRQNYPSNTGAGSPDMVYNVWRKPGDEAKYPYYPERNNRGNMKTNQNSLYIEDASFIRLASARLAYTFSPNLANKLKMKGLTTYIYGTNLLTWTNYRGYDPEFSTTNPLTPGEDDGRYPRRREFGFGVNVNF
>NZ_CP049333.1|WP_165305841.1|1505011_1507147_+|DUF5110-domain-containing-protein
MEKILIILLLLLCSHAKAQPIQWKEQYPGVWKGTFGQPEKYTLLGAAGIEPRASTLEQLQSTDFPLPKMEVHAELIDGKTYVRMPLTKNEQIYGLGLNFQTVHQRGKILNLHVDHYGGKDNGRTHAPVPFYVSSKGYGVLVNSAQYLTYYVGTAVRKDAKEPAEAKDRNTDKSWNSRPYSDAVEIYIPAAGVEIYVFAGINPLDAIKRYNLFCGGGTLPPRWGLGFTQRIQKLYTAEEVLHEADQFEEHGFPLDFIGLEPGWQSRAYPCTFEWDKGRFPDPASLIRKLATKGIRLNLWTNPYISPEAGISKAIEPYTGSHTVWNGTVPDLNHPEAKKILAKQFMDAQLNIGVSGYKMDEVDGYDYYLWPDMAKFPSGISGIQMRQTYGVLAQKLTDSLYRSQNKRTYGLVRASNAGANNLPYVIYNDYYSHQDFITALVNSGFCGVLWTPEVRGSKTGQEWLRRFQSVVFSPMAMINAWSSGTKPWSFPEVADQVKYYAQLRMELMPYLYSEFAKYHFEGTPPFRAMVLEEGFQGQSKAVLGNQDLETNPYLEAVSREVKDQYMCGEYILVAPLFVGESSRKVLLPKGNWYDFYTGKYVGNGEEIVASPDMDRIPVYVKDGGIIPMMCSRLHAPLSNEKVDLTIRHYGEKEGSYRLYDDDGVSFDYEKGSYAWRRVLVKKNEKGSLSGEISKPQQGKPNTFGRVQFEFMTK
>NZ_CP049333.1|WP_165305840.1|1503881_1505006_+|glycosyl-hydrolase
MRSILSGIAVSLALYAPAQNIDLKNWPEAANPMTVGRLVAQRFVESPHNSFKPPAPPKSITYPEVCTWYGALKFAEISQDKALLDKLTQRFMPFFDTEKHLVPRPWHVDFAVFGTVPLELFRQTKNKTFREMGMRFADAQWSIPIDSPQTVKDSYQKFLDKGLTWQTRYWIDDMYMITMLQSKAFQVTGKRKYIDRAAHEMLVYLDTIQKENGLFYHAPDAPFFWGRGNGWMAAGMSELLSALPKDNLNRPAILASYKKMMASLKKYQREDGLWGQLIDRPESWAETSGSAMFTYALITGVRNGWLDASEYTPIARKAWLALVGYINKEGDIANVCEGTNRKNDYQYYLDRKQKTGDMHGQAPILWCIYALLKK
>NZ_CP049333.1|WP_165305839.1|1502582_1503752_+|divalent-metal-cation-transporter
MKQKNTSALIGAALLMATSAIGPGFLTQTTVFTKSLGASFGFVILVSILIDIGVQLNIWRVIAVSEMRAQDIANKLLPGLGGFISLLIILGGLAFNIGNIAGAGLGLEALFGVHVMTGACISALIAIAVFINKQIGKAMDRFTQFMGAIMILAFIYITLISSPPLGEAVLRTVAPAKIDFVSIITLVGGTVGGYITFAGGHRLIDAGVKGFNALPTVNRSAIMGISVASLVRVCLFLAALGVLSQGLLIEDGNPTASVFRLAAGNFGYRLFGLVMFAASITSIIGSAYTSVSFIKTFSARIAKNENWVIIAFILISTIIFVSVGKPVHLLIIAGAVNGIILPVSLTVMLIAAYKPAIVGVYKQPLILTLIGVTIVVLMAFMSLRVMMDL
>NZ_CP049333.1|WP_165305838.1|1501827_1502586_+|LamB/YcsF-family-protein
MNKQLTVDLNCDLGESFGSWKMGDDEAILPYVSAVNIACGFHAGDPATMMRTVQLALKYKVKIGAHPGFPDLVGFGRREMQLSAREVYELVVYQVGALAACAKVQQTTLQHVKPHGALYNMAARKLELADAIAAAIYDIDPGLILYGLSGSELIRAGRAKGLNVYSEVFADRTYQQDGTLTARSDKHALIHDPERAAEQVVGMIKTGKVISLQGTAVDIRADTICLHGDGEEAVQFAKTINQTLKDKQILIR
>NZ_CP049333.1|WP_165305837.1|1500878_1501835_+|biotin-dependent-carboxyltransferase-family-protein
MGIKIVKAGMLTTIQDLGRYGLQRYGMAVSGAMDSYALRLGNNLLGNPDNEAAIECTVLGPIIYFEQAQLICLTGADLSPMIDGNPLPMWRPVPIEAGSLLSFGRPHLGCRAYICFQGGLDIPEILGSRSTYSKGGLGGWQGRALHEGDRIAFRHHYTGKDSLFHWSMDPGLYPDLTTEVIRVLDGPQFACFESNAQKSFFSDVFNISNNSDRMGYRLTSKPLRLTEQKELLSTAVTFGSIQVPPDGNAIILMADHPTTGGYPVIAQVATIDLPLLAQKGPNDRISFERVSLDEAHGLLKKQHTQLKKLKSAIALKYE
>NZ_CP049333.1|WP_165305847.1|1518562_1519375_+|sigma-70-family-RNA-polymerase-sigma-factor
MKLLLLNKDIKTAIEHLHNGHEKGLKFFYQKFYEHFFFRAHRATDDECAGESIAQEAFLRLWLFRENVHSESEVFEFLKVQVKSAIQAFYQKSRNRFHRSLLRLDSIEDYQEFMLGYELEEESEADLLYIEQLELEKKKKMDQINAILPNLNSDQQLFIRLCLKYSFNYERIAYYMGNISDYEVGLHMEKTIEYLRSIIHSEEKMQLMAKPVEFKLNDEMTEEEAEVFRMRYELQYSFDKISEALQLDGGQVRTLFINAHAKIKSAKKTA
>NZ_CP049333.1|WP_165305848.1|1519391_1520486_+|hypothetical-protein
MAADTMVLTRKIQVFVDCDDKEKRSGYFKQLFEWQDLVFRGANMVITHQYVQENLKDLIYLQEDVKIKLADQAKDPEGVLNTSRMNTTYRLLSSYFKGRIPTDILSQINTALIKYFQADRLSYWKGEKSLRNYKKDMPIPFSGRQINLSKDENNRDFKFTLFKIPFRTYLGKDRSDKKVLLQRALVGQIKICSSAIKIVKGKIFLLLALELPKKIQELKDNVIAEASLSIEHPIAVTIGKESFQIGNKEEFTYRRMAIQAARHRLQKAAAFDKGGRGRKRKMKSLEHYNEKEKNYVDTKLHLYSRRLIELCVKAQAGTLLLVNQSNKEEMAKGDEFLLRNWSYYGLIEKIKYKAKMVGINIIIE
>NZ_CP049333.1|WP_165305849.1|1520487_1521057_-|hypothetical-protein
MEKSIAQHIGDNKRPTSQTTFRHDRENDYVSIGNRIFYRDKMVEDVDAGSFKDLGNAYARDNWNAYYRGIKIKDVSPHSFQSLGWGYAKDSWNAYYRGVKIKDVSAPSFKVLDEGYAKDSWNVYYRGNQIKDVSAPSFVLLGDGYSKDSWKVYYFGREIKDATAFTFEYLGKGYAKDSWNEYYRGKKLE
>NZ_CP049333.1|WP_108632869.1|1521278_1521584_+|hypothetical-protein
MSFKEKLENWRTSINRAGSGEELYILLLNYKKFINKNWMDDFGDPGNWKSELNQVISKVRKKVDVADIRNCEDLSSYQDDARQTAHSLNNTLKYHHSLTKG
>NZ_CP049333.1|WP_165305850.1|1523327_1526501_+|TonB-dependent-receptor
MTKGYAQEQLRKLSGTVVDTLGAGIAGVSIVATEGRAGATKTDAQGKFQLDVSTGNVLKFSIVGYQQQFLTVQPNQLTVTIHMKSTSNEIGEVVVTAMGQKQRREAIVGAVTSVRPGDLKVPASNLTNALAGKVAGVIAFQPSGQPGQDNSNFFIRGVTTFGYKKDPLILIDNVEMTSSDLARLQVDDIESFSILKDASSTALYGARGGNGVILVKTKEGKSGRAKIDVRLERSASESVKNLQLADPITYMKLYNEATLTRNPSAVPLYTPNKIMNTQASMEGAPGSNPFVYPAVNWMDMLFKKRTSTERANLNVSGGGGVARYYIAGSYSNDAGILKTDIRNNNNNNVSFKNYQLRSNVNIDLTKSTELVVRLSGNFNEYRGPMTNDPSFATDLYNIAMHTSPVDFPAFYEPDAANAGVQHILFGNNTDATVLPDGSTLPSSSTDVKNINPYAALLRGNRRFSESRMLAQLELNQKLDFITKGLNFRSIFSTNRYARFESELAYAPYFYNVKSYDKASNQYTLNWINNKPDQAREYLNYYAGASTLNTFLYLQGVLDYAADLNENHNISAALIGTQQQQLNANAKTLFTSLPYRNLGLSGRATYAYKSRYFLEFNFGYNGSERFSENHRYGFFPTMGASWIISDEKFYGHFSNVINRMKLRGSYGLVGNDAISDRRFFYLSDVNLNGGNPAYFGINNGYSHNGVTINNYENRDVTWEISRQINLGLELTFLKNIKLITEVYKNYKSDILQDRANIPTTMGLEAGINANIGKVESQGIEFSLDGKHNFSNDLWISSIANFTFAKNKYTQYEEPDYNEKYRLHTGVAINRNYGYIAERLFVDDTEAQNSPTQIFSSNGIAPRGGDIKYRDLNGDGVVDGKDQTWFGNPTVPEIVYGFGLSSGYKNFDLSVFFQGQARVSFVIDPARTSPFIKSPDSWLPGNTQVIQQYADDHWSEDNQNLYALYPRLGTNGAEIENNRQNSTWWLRDGSFIRMKSLEFGYRFPTKLLNRIKVRNLRVYFSGLNLLTWSPFKMWDPELGGNGFAYPLQKVYNLGINLGI
>NZ_CP049333.1|WP_165305851.1|1526526_1528464_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKTSYSKFLYMAVLIISTVSCKKYLNVTPDNVGTIDYAFRNRNEAENYLFTCYSTLQQMNTPWLDAGFSTSGEIIYPAPNEINDNQGLNPVGFNIMRGTQNAGKPGLNYWDGTEGGQAIFKAIRRCNTMLENIDKPIDLGESEKKRWIAETKFLKAYYHFYLFRMYGPIPIIDVNLPINSSIEDVKVKRAPVDSVVNYMVRLIDEAIPNLPIQIQNPQLELGRITGLIALSVKAQILTTAASPLFNGNPDYIGFSNKDGQPLFNQAKDNTKWDRAAQACSEALNACLANGLRLHTFTPTAAMPANLPKELKDVLTMQTAITEKWELNTELIWGLNPVFGFGLQERFIPRLSAASATNLSSAQGTLSVPIAQQELFYTANGLPIEEDKTWDYRNRYALKTATATDQYHVHNGYETVAAHFKREPRFYAAIAFDGGVWYGNGELNNPTNAFYVQAKGTTSYAGPKDQSHTNITGYWVKKLVNYLTVYGTQMTYENFHFPLMRLSDLYLMYAEVLNEQGKNYSEVLPYIDIVRARANIPAIEDAYTPALSTNPSKYTTQSGLRQIIHQERRIELAFECVPGWDLRRWKELQGVMSKPIQGWNIYNEQSVNYYRPLTLFVPVFSAKNYLWPINSDNFPVNNNLVQNPLW
>NZ_CP049333.1|WP_165305852.1|1528478_1529705_+|DUF4959-domain-containing-protein
MINIKKYTLPLFLLIMVSIISSCKKNNGFNAVISEDTSKPLPVSNVKVDNFTGGANITYNLPNSPNILYVLAKYRVNDNLVRETKSSYYKDTVVVEGFAKEQPYEVTLYTVTRANIMSDPVTVTVNPKIPAYLETRPSLVLSPDFSGVNITGNNPSGKQISIVLLSFNKNTGLMEIEDQFVTKNTKIDHSVFGFNAVERRFAVYVADRWGNLSDTLQTSLTPLFEEAMDKNKFSTLNLSTDTPIDFNWQVQNLWDGRADGSGWHTKFGEPLPYSCSFGIGKTYKLSRFVLFERTGSQYTYKYANPKEFSLWGTNAAIPDNVKLPVRADEGTVIGNWVNLGNFVFPDPPSGNAPANSTAADEDFVKQGVSFRVPFGAPPVKYLRIAVSTVWGREAGAHLMEVTPYGTPE
>NZ_CP049333.1|WP_165305853.1|1529729_1530929_+|hypothetical-protein
MKNNLTTLICCLLALLASCSKQQTDFRDLLGGHEIVYTGLVGQVIEKPGNLRTILTWKKSSDPSIVKYVIFYNQKDSVVVDVTDKKDSVSATITNLEEAVYTFTIYSYDAKGNKSVPKLLNAKIYGPIYQASLLNRPYNGDVPYVAFDNGKVELNFNKPDTVNVTTTVKYTTTANTIKEADLAPTDSILYLNDYKPGTEITYRSFYKPTRNAIDVFSTTSDAVFPQIYFNILCDKSLFRELSLPNDVGTLAESPLRNLWDGSVGPQGYPNIYHSQGNVPLPHTISFDMGKIYNNLSILEETGRNCCHNPDQFEVWGIADISNAATTLPANDAGWKDEAIRKGWTLLLDAVRTDDGSAAKKFELIKNPPPVRYIRIRVKHNANGDTNQSNMSELSFWNGQ
>NZ_CP049333.1|WP_165305854.1|1531007_1533035_+|alpha-galactosidase
MKYFFGILLLLAASMTLSGQTLQIKKNRITFNYNKAKGTYSIGSERQLFINQAVSYLRLANGQKISTDKLTGTRSVTEKPVQDNLGKGIQYTISVKAQQGITLLQHFYFYDTIDGVILEMEVRGKNIASNELVPIWSNASITGLGKSLYQLAVPFDNDTFISYENNVLAMNNKSSSAEVGVVYDKYSGKGLLIGSLDQSVWKSGIAIKGDQGQYTHLAAQAGFTDVNITRDSMAHGAVKGDVIRSPKYLVSYDKDWRIGLENYAKIHRKLSPAYVKSWQGATPVGWNSWGVIQEKLNFQNATGTADYFAKDIPYFRNADGEAFIDLDSFWDNMTPGGMSGDYTQLKQFVLYCDSLGLKPGVYWAPFTDWGHGSGPDRKAEGSQFTFGQLWTKTQKGYHNLDGGRALDPTHPGTLARMDVILGKLVDCGFRMIKVDFLSHAAIESTGFYDKKIQTGMQAYAVGMKHLVDVLQGKMLIYAAISPSLATAQFAHMRRIACDAWKTIDQTQYTLNSVSYGWWQTYLYDFIDADHLVFHDESPEVNKARLLSGVVTGTIILGDDLSKKENWQPKMNQYLQDPEILKIIADGKSFRPAGFVEGKAANTYYYKKIGTALYVAVFNYNTAPAAINIDFKQIGLAPNTTYKAVELFEKAAQEFSAEKSIAFEQAGAKLFKVALF
>NZ_CP049333.1|WP_165305855.1|1533044_1534085_+|GntR-family-transcriptional-regulator
MKKSKEEHFKVLIDRIKRLEALNTLSKHECIVQGVLDAIDANELEVHASLPSVNNLIQYLGYARETFAKAYRDLIAHGVVESKNRKGYFVVSNNTQMKQKVAVLLYAYDTFQDTLVNELRTNLPEEVTVDLFFHHNNMETFEDIFNRIQGRYTVYIVAPIENKDSELLLRSIPASKLLIIDRLVDLGEDYSYVSQEFEEATYAVFQELYPKIKKYKEVIFYFRENTAEPNEIKDAFLRFLKEYKVKGRIEKQYHVGDLKKGKLYFTIHNPELYQMLKEVLQKGWTLGEDLGILSHNDDVIKEIISGGITTFSTSFARIGSQAAKFVLERTLIKEVVPTTLADRNSV

Crispr_ID: NZ_CP049333_2

• CRISPR_ID: NZ_CP049333_2
• CRISPR_location: 1517237-1517467
• CRISPR_type: TypeV-U3
• Repeat_type: NA
• Spacer_info: 3 spacers
• Cas_protein_info: c2c10_CAS-V-U3

Consensus repeat of NZ_CP049333_2

Consensus_repeat	Method
GATGTTGATGACCTCAAAAAGTAGGGTATACACAAC	PILER-CR
GATGTTGATGACCTCAAAAAGTAGGGTATA	CRISPRCasFinder
GATGTTGATGACCTCAAAAAGTAGGGTATACACAACN	CRT

spacers of NZ_CP049333_2

>2.1|1517273|29|NZ_CP049333|PILER-CR,CRT
TTAACGCTAACCTTTATCATTTAATTGGT
>2.2|1517338|29|NZ_CP049333|PILER-CR,CRT
TTAGGGGCTAGATTATTCGGTATAATTTT
>2.3|1517403|29|NZ_CP049333|PILER-CR,CRT
AGTGCTCTATTCAAGCGTTCACAACTTAA
>2.4|1517267|35|NZ_CP049333|CRISPRCasFinder
CACAACTTAACGCTAACCTTTATCATTTAATTGGT
>2.5|1517332|35|NZ_CP049333|CRISPRCasFinder
CACAACTTAGGGGCTAGATTATTCGGTATAATTTT
>2.6|1517397|35|NZ_CP049333|CRISPRCasFinder
CACAACAGTGCTCTATTCAAGCGTTCACAACTTAA

CRISPR arrays and Neighbor proteins around NZ_CP049333_2

CRISPR arrays

The CRISPR arrays of NZ_CP049333_2

>merge|NZ_CP049333|2|1517237-1517467|PILER-CR,CRISPRCasFinder,CRT
GATGTTGATGACCTCAAAAAGTAGGGTATACACAACTTAACGCTAACCTTTATCATTTAATTGGTGATGTTGATGACCTCAAAAAGTAGGGTATACACAACTTAGGGGCTAGATTATTCGGTATAATTTTGATGTTGATGACCTCAAAAAGTAGGGTATACACAACAGTGCTCTATTCAAGCGTTCACAACTTAAGATGTTGATGACCTCAAAAAGAGGGTATAAACAACT

>NZ_CP049333|2|1|1517237-1517466|PILER-CR
GATGTTGATGACCTCAAAAAGTAGGGTATACACAAC	TTAACGCTAACCTTTATCATTTAATTGGT
GATGTTGATGACCTCAAAAAGTAGGGTATACACAAC	TTAGGGGCTAGATTATTCGGTATAATTTT
GATGTTGATGACCTCAAAAAGTAGGGTATACACAAC	AGTGCTCTATTCAAGCGTTCACAACTTAA
GATGTTGATGACCTCAAAAAGAGGGTATAAACAAC

>NZ_CP049333|2|2|1517237-1517462|CRISPRCasFinder
GATGTTGATGACCTCAAAAAGTAGGGTATA	CACAACTTAACGCTAACCTTTATCATTTAATTGGT
GATGTTGATGACCTCAAAAAGTAGGGTATA	CACAACTTAGGGGCTAGATTATTCGGTATAATTTT
GATGTTGATGACCTCAAAAAGTAGGGTATA	CACAACAGTGCTCTATTCAAGCGTTCACAACTTAA
GATGTTGATGACCTCAAAAAGAGGGTATAAA

>NZ_CP049333|2|2|1517237-1517467|CRT
GATGTTGATGACCTCAAAAAGTAGGGTATACACAAC	TTAACGCTAACCTTTATCATTTAATTGGT
GATGTTGATGACCTCAAAAAGTAGGGTATACACAAC	TTAGGGGCTAGATTATTCGGTATAATTTT
GATGTTGATGACCTCAAAAAGTAGGGTATACACAAC	AGTGCTCTATTCAAGCGTTCACAACTTAA
GATGTTGATGACCTCAAAAAGAGGGTATAAACAACT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049333.1|WP_165305843.1|1510531_1512076_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl|CDD|185760
NZ_CP049333.1|WP_165305841.1|1505011_1507147_+|DUF5110-domain-containing-protein	unknown	unknown	gnl|CDD|376446
NZ_CP049333.1|WP_165305845.1|1514734_1515238_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NZ_CP049333.1|WP_165305853.1|1529729_1530929_+|hypothetical-protein	unknown	unknown	gnl|CDD|379841
NZ_CP049333.1|WP_165305848.1|1519391_1520486_+|hypothetical-protein	c2c10_CAS-V-U3	-	gnl|CDD|273793
NZ_CP049333.1|WP_165305846.1|1516328_1516838_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP049333.1|WP_108637014.1|1512100_1512868_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP049333.1|WP_165305849.1|1520487_1521057_-|hypothetical-protein	unknown	unknown	gnl|CDD|372659
NZ_CP049333.1|WP_165305838.1|1501827_1502586_+|LamB/YcsF-family-protein	unknown	unknown	gnl|CDD|377121
NZ_CP049333.1|WP_165305842.1|1507420_1510519_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|274948
NZ_CP049333.1|WP_165305840.1|1503881_1505006_+|glycosyl-hydrolase	unknown	unknown	gnl|CDD|369381
NZ_CP049333.1|WP_165305851.1|1526526_1528464_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl|CDD|369630
NZ_CP049333.1|WP_108632869.1|1521278_1521584_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP049333.1|WP_165305850.1|1523327_1526501_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|274948
NZ_CP049333.1|WP_165305852.1|1528478_1529705_+|DUF4959-domain-containing-protein	unknown	unknown	gnl|CDD|379822
NZ_CP049333.1|WP_165305847.1|1518562_1519375_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NZ_CP049333.1|WP_165305854.1|1531007_1533035_+|alpha-galactosidase	unknown	unknown	gnl|CDD|269892
NZ_CP049333.1|WP_165305855.1|1533044_1534085_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|153418
NZ_CP049333.1|WP_165305839.1|1502582_1503752_+|divalent-metal-cation-transporter	unknown	unknown	gnl|CDD|224826
NZ_CP049333.1|WP_165305844.1|1512894_1514358_+|alginate-lyase	unknown	unknown	gnl|CDD|271210

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP049333.1|WP_165305848.1|1519391_1520486_+|hypothetical-protein	c2c10_CAS-V-U3	-	9.9e-54	177.5	12.5

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP049333.1|WP_165305843.1|1510531_1512076_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl|CDD|185760	cd08977, SusD, starch binding outer membrane protein SusD. SusD-like proteins from Bacteroidetes, members of the human distal gut microbiota, are part of the starch utilization system (Sus). Sus is one of the large clusters of glycosyl hydrolases, called polysaccharide utilization loci (PULs), which play an important role in polysaccharide recognition and uptake, and it is needed for growth on amylose, amylopectin, pullulan, and maltooligosaccharides. SusD, together with SusC, a predicted beta-barrel porin, forms the minimum outer-membrane starch-binding complex. The adult human distal gut microbiota is essential for digestion of a large variety of dietary polysaccharides, for which humans lack the necessary glycosyl hydrolases.	1.40785e-34
NZ_CP049333.1|WP_165305841.1|1505011_1507147_+|DUF5110-domain-containing-protein	gnl|CDD|376446	pfam01055, Glyco_hydro_31, Glycosyl hydrolases family 31. Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases.	3.59352e-89
NZ_CP049333.1|WP_165305845.1|1514734_1515238_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.58351e-06
NZ_CP049333.1|WP_165305848.1|1519391_1520486_+|hypothetical-protein	gnl|CDD|273793	TIGR01766, Putative_transposase_MJ0751, transposase, IS605 OrfB family, central region. This model represents a region of a sequence similarity between a family of putative transposases of Thermoanaerobacter tengcongensis, smaller related proteins from Bacillus anthracis, putative transposes described by pfam01385, and other proteins. [Mobile and extrachromosomal element functions, Transposon functions].	0.00203156
NZ_CP049333.1|WP_165305844.1|1512894_1514358_+|alginate-lyase	gnl|CDD|271210	cd14251, PL-6, Polysaccharide Lyase Family 6. Polysaccharide Lyase Family 6 is a family of beta-helical polysaccharide lyases. Members include alginate lyase (EC 4.2.2.3) and chondroitinase B (EC 4.2.2.19). Chondroitinase B is an enzyme that only cleaves the beta-(1,4)-linkage of dermatan sulfate (DS), leading to 4,5-unsaturated dermatan sulfate disaccharides as the product. DS is a highly sulfated, unbranched polysaccharide belonging to a family of glycosaminoglycans (GAGs) composed of alternating hexosamine (gluco- or galactosamine) and uronic acid (D-glucuronic or L-iduronic acid) moieties. DS contains alternating 1,4-beta-D-galactosamine (GalNac) and 1,3-alpha-L-iduronic acid units. The related chondroitin sulfate (CS) contains alternating GalNac and 1,3-beta-D-glucuronic acid units. Alginate lyases (known as either mannuronate (EC 4.2.2.3) or guluronate lyases (EC 4.2.2.11) catalyze the degradation of alginate, a copolymer of alpha-L-guluronate and its C5 epimer beta-D-mannuronate.	1.88279e-154
NZ_CP049333.1|WP_165305849.1|1520487_1521057_-|hypothetical-protein	gnl|CDD|372659	pfam13644, DKNYY, DKNYY family. This family represents a group of proteins found enriched in fusobacteria. These proteins contain many repeats of a DKNXXYY motif. The repeats are spaced at about 35 amino acid residues intervals. These proteins are likely to be associated with the membrane. The specific function of these proteins is unknown.	1.69329e-19
NZ_CP049333.1|WP_165305838.1|1501827_1502586_+|LamB/YcsF-family-protein	gnl|CDD|377121	pfam03746, LamB_YcsF, LamB/YcsF family. This family includes LamB. The lam locus of Aspergillus nidulans consists of two divergently transcribed genes, lamA and lamB, involved in the utilisation of lactams such as 2-pyrrolidinone. Both genes are under the control of the positive regulatory gene amdR and are subject to carbon and nitrogen metabolite repression. The exact molecular function of the proteins in this family is unknown.	3.51543e-148
NZ_CP049333.1|WP_165305842.1|1507420_1510519_+|TonB-dependent-receptor	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0
NZ_CP049333.1|WP_165305840.1|1503881_1505006_+|glycosyl-hydrolase	gnl|CDD|369381	pfam07470, Glyco_hydro_88, Glycosyl Hydrolase Family 88. Unsaturated glucuronyl hydrolase catalyzes the hydrolytic release of unsaturated glucuronic acids from oligosaccharides (EC:3.2.1.-) produced by the reactions of polysaccharide lyases.	7.73875e-50
NZ_CP049333.1|WP_165305851.1|1526526_1528464_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl|CDD|369630	pfam07980, SusD_RagB, SusD family. This domain is found in bacterial cell surface proteins such SusD and SusD-like proteins, as as well RagB, outer membrane surface receptor antigen. Bacteroidetes, one of the two dominant bacterial phyla in the human gut, are Gram-negative saccharolytic microorganisms that utilize a diverse array of glycans. Hence, they express starch-utilization system (Sus) for glycan uptake. SusD has 551 amino acids, and is almost entirely alpha-helical, with 22 alpha-helices, eight of which form 4 tetra-trico peptide repeats (TPRs: helix-turn-helix motifs involved in protein-protein interactions). The four TPRs pack together to create a right-handed super-helix. This is predicted to mediate the formation of SusD and SusC porin complex at the cell surface. The interaction between SusC and TPR1/TPR2 region of SusD is predicted to be of functional importance since it allows SusD to be in position for oligosaccharide capture from other Sus lipoproteins and delivery of these glycans to the SusC porin. The non-TPR containing portion of SusD is where starch binding occurs. The binding site is a shallow surface cavity located on top of TPR1. SusD homologs such as SusD-like proteins have a critical role in carbohydrate acquisition. Both SusD and its homologs, contain about 15-20 residues at the N-terminus that might be a flexible linker region, anchoring the protein to the membrane and the glycan-binding domain. Other homologs to SusD have been examined in Porphyromonas gingivalis such as RagB, an immunodominant outer-membrane surface receptor antigen. Structural characterization of RagB shows substantial similarity with Bacteroides thetaiotaomicron SusD (i.e alpha-helices and TPR regions). Based on this structural similarity, functional studies suggest that, RagB binding of glycans occurs at pockets on the molecular surface that are distinct from those of SusD.	2.50181e-46
NZ_CP049333.1|WP_165305850.1|1523327_1526501_+|TonB-dependent-receptor	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0
NZ_CP049333.1|WP_165305852.1|1528478_1529705_+|DUF4959-domain-containing-protein	gnl|CDD|379822	pfam16323, DUF4959, Domain of unknown function (DUF4959). This family consists of uncharacterized proteins around 400 residues in length and is mainly found in various Bacteroides, Pedobacter and Parabacteroides species. Several proteins are annotated as Galactose-binding like proteins, but the specific function of this protein is unknown.	4.21279e-38
NZ_CP049333.1|WP_165305847.1|1518562_1519375_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	0.00620894
NZ_CP049333.1|WP_165305854.1|1531007_1533035_+|alpha-galactosidase	gnl|CDD|269892	cd14791, GH36, glycosyl hydrolase family 36 (GH36). GH36 enzymes occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-galactosidase, alpha-N-acetylgalactosaminidase, stachyose synthase, and raffinose synthase. All GH36 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH36 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.	2.00903e-10
NZ_CP049333.1|WP_165305855.1|1533044_1534085_+|GntR-family-transcriptional-regulator	gnl|CDD|153418	cd07377, WHTH_GntR, Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators. This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.	3.56462e-10
NZ_CP049333.1|WP_165305839.1|1502582_1503752_+|divalent-metal-cation-transporter	gnl|CDD|224826	COG1914, MntH, Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism].	1.05695e-61
NZ_CP049333.1|WP_165305853.1|1529729_1530929_+|hypothetical-protein	gnl|CDD|379841	pfam16389, DUF4998, Domain of unknown function. This family around 200 residues locates in the N-terminal of some uncharacterized proteins in various Bacteroides and Parabacteroides species. The function of this family remains unknown.	5.42893e-48

Protein sequences

>NZ_CP049333.1|WP_165305846.1|1516328_1516838_-|hypothetical-protein
MYTLLFEVINIKLRLNISNARVVYTLHFEIINILEEVVYPNYLSCVYPTFWDHQHLASADIISIPVVYTPLFEVINMEKGLLYKEDIAVYTLHFEIINIIWISATAGLFSPTSQWQQLSTYKEAILPKNACALYRIKGMMAYLRIVLLQLAIEMPRTVYKLRQIAAILA
>NZ_CP049333.1|WP_165305845.1|1514734_1515238_-|helix-turn-helix-transcriptional-regulator
MGDINEQILEEIGEQLRIQREKIYYTLKDVANMTGLTTNTIAAVERGKGASLNNFILICRALNIQPHTIFKKEIDLTPLYNIPPESKRRIEMTKELDDLVYNSNFFEIPRRVSDIIQQLNANKEQSNKFSVYLSSYCQEGTLEYEKHGNYKEYRKKHSPKPVKKYSK
>NZ_CP049333.1|WP_165305844.1|1512894_1514358_+|alginate-lyase
MNAKKMVFASLSLLLVIGSSCEKPVMINMQLNGVACVQCHTIQSAADLQALSLHPGDTVIMKSGQWTDQELTFAAQGTSQQPIVLMAEQPGTVILKGMSSVSITGKWLVVSGLVFQNGYTSGKNVIDFTSSSSNCRLTNSAIVDYNPPTATTDYRWVSINGSNHRVDHCYLKGKSHQGPTMVVWGTNKTMKHRIDHNFFGKRAELANNGGETIRIGTSDWSMTNAYTTIEDNIFQRCNGEMEIISNKMGADTIRNNFFHESQGTLCLRHGNGSAVYGNYFVGNGNSAAGGIRIIGEDHIVYNNYFQHMSGTGQKAPLVLMDGVPNSPLSGYYQVKRVKVVANTMIKCKQSFDIGSGKGGSSRTLPPTDGHIANNVVSQVATSTMLTFTDQPINFTYQGNIVYDVPTSQQLPAGFTRQNPQYTLTAEGIYEPTGNSPVLGAFVGNYPFAAAADAGAPKLDNKHRDLLKAQNIGPGFMTGLGNSLVINP
>NZ_CP049333.1|WP_108637014.1|1512100_1512868_+|hypothetical-protein
MKRNFNIKWIQVGVMLLTLLTTGCSLFDMELQENYDYEHKTLDPNIGISARKFLENRSYGTPENPTDTAFKWMRMGLEYAGIDLNELEKADRTFIFLHNDAIKIWDVKTKKVTGGLFLDFPIVTGVDGTGKPLTKPAAKWEDYSKEDVRNYFLYLILQGKYNFADLSIDNVKAKTLLPANTVASKGSLLGYLNEGKGFDQEGAMYLKLVNNSDLAPIQINNKTTNRSGGYGVTNGVVHVYGVKGNTTVYPFISLQ
>NZ_CP049333.1|WP_165305843.1|1510531_1512076_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MYKIKILAALLFLGTLGGCNKFLDEKPLADGTLDQHYKNMYDVQAAMAGMYSAFQLEMVGKEQYTEKYLYWGEYRSDNFDRFISYTKDYVDEIVLNSITPSNDFSDWSGLYTTIGRANNNIKYIPQAAQLDSRITMAMQNDYLAQSYALRAMSYFYIVRVWGDAPIWLEPYEDVQQPAERAREPKEKLLKDVIIPDLEKAYSLITKDARSPLWTIGEAGICAIMADVYMWQGDHENAIKWIEKLFLAKSPTNVTYAGLNETNLQDAATWKTIFTNPSSSKETIWSIHWDYLKNGCACMQTSWTSNNKQVIVDEGIWTSWFLPQTTSTPSPDIRPKQTLDVYFGMPSNKRDRFIKWYPTEANPTKADPWPATNQLLPVYLTMYRLSDIYLLYAEALNARGDREKAIKYLNFVRKRAQLPAYDVSAPELATPYALETAILNERQLELFGEGKRWFDLVRTNRVKVVMDPILKRRQEDAGNLEMPGFLDPKNRAYWPLNRNVLNSNSLLVQNPGYTD
>NZ_CP049333.1|WP_165305842.1|1507420_1510519_+|TonB-dependent-receptor
MMKSITKMGCFVLCLFLLMGSMGLPLFAQQNIRISGKVSNSKGDALQGVSVRIKGKSQGTSTDAAGKYQLEAAPTNILVFSQVGMKEEERAIGSQRQIDVQLVESDNALDEIVVTGYGSVAKKRDLTGAISSVSAKKIQERQPINLFDALQGQAAGVLIVNDGGGAPGATGSIQVRGTSTLNGGNGPLYLVDGVINPDGANINPTDIENIEVLKDAASASIYGSRAANGVILITTKRGAEGKPLINVNYNHLFGRLAHYIPVSNSAEVREFRNIQGQNSNIDSLNPSFNADNDLQKLLLGNLAQKKEIKLSIGGGQKNLRYYSSLNYLDDKSIILNSYAKRLQSRINVEYQASSKLRYSNNISFAWQKGNSIPIANTVRVVMDRPAYSLIYYPDGSLTSYVGSKRNPVANALYEQNIDETYSGQFNNQLDYQLTNDLKLTTLFNARLDNLQNTGFSPRFLSANKDQNNGSNEFTKTFSWEFQAFANYNKTFAQDHNVYALLGFSADRRRFDRFHSEYLNSVNEEVLVTFPDYLTSSKTYTSATANATASLFSRVGYNYKSRYLLQASYRRDGSSRFGPSNKWGNFFSGSAAWRFSDENFMKWAKPALQDAKLRYSFGQLGNDKIGDYESYAKVAFGGNYNGVGGASMTPTLGNYLIKWEMTTQNNVGLDLTFLNGRLGFTADYYVKTTTDLLYPRELPKETGYTKLQVNVGSIRTRGMEFVVNARPIVQSNFTWEINGNISFERGKVVKLADGIPFFPGNKWYLEEGGRIGNFYGWRNLGVYAWDESNAYNDNWDKLTLVLDDQGKPLYRDGKPVYTSDGQNYEGPVHHLYAPDGKLKGGDAEWFNNKRDSLINDDDRMILGNPTPDFYFGFMQTFTYKRFSLNVLFNGAIGGEVYNALLQRQNYPSNTGAGSPDMVYNVWRKPGDEAKYPYYPERNNRGNMKTNQNSLYIEDASFIRLASARLAYTFSPNLANKLKMKGLTTYIYGTNLLTWTNYRGYDPEFSTTNPLTPGEDDGRYPRRREFGFGVNVNF
>NZ_CP049333.1|WP_165305841.1|1505011_1507147_+|DUF5110-domain-containing-protein
MEKILIILLLLLCSHAKAQPIQWKEQYPGVWKGTFGQPEKYTLLGAAGIEPRASTLEQLQSTDFPLPKMEVHAELIDGKTYVRMPLTKNEQIYGLGLNFQTVHQRGKILNLHVDHYGGKDNGRTHAPVPFYVSSKGYGVLVNSAQYLTYYVGTAVRKDAKEPAEAKDRNTDKSWNSRPYSDAVEIYIPAAGVEIYVFAGINPLDAIKRYNLFCGGGTLPPRWGLGFTQRIQKLYTAEEVLHEADQFEEHGFPLDFIGLEPGWQSRAYPCTFEWDKGRFPDPASLIRKLATKGIRLNLWTNPYISPEAGISKAIEPYTGSHTVWNGTVPDLNHPEAKKILAKQFMDAQLNIGVSGYKMDEVDGYDYYLWPDMAKFPSGISGIQMRQTYGVLAQKLTDSLYRSQNKRTYGLVRASNAGANNLPYVIYNDYYSHQDFITALVNSGFCGVLWTPEVRGSKTGQEWLRRFQSVVFSPMAMINAWSSGTKPWSFPEVADQVKYYAQLRMELMPYLYSEFAKYHFEGTPPFRAMVLEEGFQGQSKAVLGNQDLETNPYLEAVSREVKDQYMCGEYILVAPLFVGESSRKVLLPKGNWYDFYTGKYVGNGEEIVASPDMDRIPVYVKDGGIIPMMCSRLHAPLSNEKVDLTIRHYGEKEGSYRLYDDDGVSFDYEKGSYAWRRVLVKKNEKGSLSGEISKPQQGKPNTFGRVQFEFMTK
>NZ_CP049333.1|WP_165305840.1|1503881_1505006_+|glycosyl-hydrolase
MRSILSGIAVSLALYAPAQNIDLKNWPEAANPMTVGRLVAQRFVESPHNSFKPPAPPKSITYPEVCTWYGALKFAEISQDKALLDKLTQRFMPFFDTEKHLVPRPWHVDFAVFGTVPLELFRQTKNKTFREMGMRFADAQWSIPIDSPQTVKDSYQKFLDKGLTWQTRYWIDDMYMITMLQSKAFQVTGKRKYIDRAAHEMLVYLDTIQKENGLFYHAPDAPFFWGRGNGWMAAGMSELLSALPKDNLNRPAILASYKKMMASLKKYQREDGLWGQLIDRPESWAETSGSAMFTYALITGVRNGWLDASEYTPIARKAWLALVGYINKEGDIANVCEGTNRKNDYQYYLDRKQKTGDMHGQAPILWCIYALLKK
>NZ_CP049333.1|WP_165305839.1|1502582_1503752_+|divalent-metal-cation-transporter
MKQKNTSALIGAALLMATSAIGPGFLTQTTVFTKSLGASFGFVILVSILIDIGVQLNIWRVIAVSEMRAQDIANKLLPGLGGFISLLIILGGLAFNIGNIAGAGLGLEALFGVHVMTGACISALIAIAVFINKQIGKAMDRFTQFMGAIMILAFIYITLISSPPLGEAVLRTVAPAKIDFVSIITLVGGTVGGYITFAGGHRLIDAGVKGFNALPTVNRSAIMGISVASLVRVCLFLAALGVLSQGLLIEDGNPTASVFRLAAGNFGYRLFGLVMFAASITSIIGSAYTSVSFIKTFSARIAKNENWVIIAFILISTIIFVSVGKPVHLLIIAGAVNGIILPVSLTVMLIAAYKPAIVGVYKQPLILTLIGVTIVVLMAFMSLRVMMDL
>NZ_CP049333.1|WP_165305838.1|1501827_1502586_+|LamB/YcsF-family-protein
MNKQLTVDLNCDLGESFGSWKMGDDEAILPYVSAVNIACGFHAGDPATMMRTVQLALKYKVKIGAHPGFPDLVGFGRREMQLSAREVYELVVYQVGALAACAKVQQTTLQHVKPHGALYNMAARKLELADAIAAAIYDIDPGLILYGLSGSELIRAGRAKGLNVYSEVFADRTYQQDGTLTARSDKHALIHDPERAAEQVVGMIKTGKVISLQGTAVDIRADTICLHGDGEEAVQFAKTINQTLKDKQILIR
>NZ_CP049333.1|WP_165305847.1|1518562_1519375_+|sigma-70-family-RNA-polymerase-sigma-factor
MKLLLLNKDIKTAIEHLHNGHEKGLKFFYQKFYEHFFFRAHRATDDECAGESIAQEAFLRLWLFRENVHSESEVFEFLKVQVKSAIQAFYQKSRNRFHRSLLRLDSIEDYQEFMLGYELEEESEADLLYIEQLELEKKKKMDQINAILPNLNSDQQLFIRLCLKYSFNYERIAYYMGNISDYEVGLHMEKTIEYLRSIIHSEEKMQLMAKPVEFKLNDEMTEEEAEVFRMRYELQYSFDKISEALQLDGGQVRTLFINAHAKIKSAKKTA
>NZ_CP049333.1|WP_165305848.1|1519391_1520486_+|hypothetical-protein
MAADTMVLTRKIQVFVDCDDKEKRSGYFKQLFEWQDLVFRGANMVITHQYVQENLKDLIYLQEDVKIKLADQAKDPEGVLNTSRMNTTYRLLSSYFKGRIPTDILSQINTALIKYFQADRLSYWKGEKSLRNYKKDMPIPFSGRQINLSKDENNRDFKFTLFKIPFRTYLGKDRSDKKVLLQRALVGQIKICSSAIKIVKGKIFLLLALELPKKIQELKDNVIAEASLSIEHPIAVTIGKESFQIGNKEEFTYRRMAIQAARHRLQKAAAFDKGGRGRKRKMKSLEHYNEKEKNYVDTKLHLYSRRLIELCVKAQAGTLLLVNQSNKEEMAKGDEFLLRNWSYYGLIEKIKYKAKMVGINIIIE
>NZ_CP049333.1|WP_165305849.1|1520487_1521057_-|hypothetical-protein
MEKSIAQHIGDNKRPTSQTTFRHDRENDYVSIGNRIFYRDKMVEDVDAGSFKDLGNAYARDNWNAYYRGIKIKDVSPHSFQSLGWGYAKDSWNAYYRGVKIKDVSAPSFKVLDEGYAKDSWNVYYRGNQIKDVSAPSFVLLGDGYSKDSWKVYYFGREIKDATAFTFEYLGKGYAKDSWNEYYRGKKLE
>NZ_CP049333.1|WP_108632869.1|1521278_1521584_+|hypothetical-protein
MSFKEKLENWRTSINRAGSGEELYILLLNYKKFINKNWMDDFGDPGNWKSELNQVISKVRKKVDVADIRNCEDLSSYQDDARQTAHSLNNTLKYHHSLTKG
>NZ_CP049333.1|WP_165305850.1|1523327_1526501_+|TonB-dependent-receptor
MTKGYAQEQLRKLSGTVVDTLGAGIAGVSIVATEGRAGATKTDAQGKFQLDVSTGNVLKFSIVGYQQQFLTVQPNQLTVTIHMKSTSNEIGEVVVTAMGQKQRREAIVGAVTSVRPGDLKVPASNLTNALAGKVAGVIAFQPSGQPGQDNSNFFIRGVTTFGYKKDPLILIDNVEMTSSDLARLQVDDIESFSILKDASSTALYGARGGNGVILVKTKEGKSGRAKIDVRLERSASESVKNLQLADPITYMKLYNEATLTRNPSAVPLYTPNKIMNTQASMEGAPGSNPFVYPAVNWMDMLFKKRTSTERANLNVSGGGGVARYYIAGSYSNDAGILKTDIRNNNNNNVSFKNYQLRSNVNIDLTKSTELVVRLSGNFNEYRGPMTNDPSFATDLYNIAMHTSPVDFPAFYEPDAANAGVQHILFGNNTDATVLPDGSTLPSSSTDVKNINPYAALLRGNRRFSESRMLAQLELNQKLDFITKGLNFRSIFSTNRYARFESELAYAPYFYNVKSYDKASNQYTLNWINNKPDQAREYLNYYAGASTLNTFLYLQGVLDYAADLNENHNISAALIGTQQQQLNANAKTLFTSLPYRNLGLSGRATYAYKSRYFLEFNFGYNGSERFSENHRYGFFPTMGASWIISDEKFYGHFSNVINRMKLRGSYGLVGNDAISDRRFFYLSDVNLNGGNPAYFGINNGYSHNGVTINNYENRDVTWEISRQINLGLELTFLKNIKLITEVYKNYKSDILQDRANIPTTMGLEAGINANIGKVESQGIEFSLDGKHNFSNDLWISSIANFTFAKNKYTQYEEPDYNEKYRLHTGVAINRNYGYIAERLFVDDTEAQNSPTQIFSSNGIAPRGGDIKYRDLNGDGVVDGKDQTWFGNPTVPEIVYGFGLSSGYKNFDLSVFFQGQARVSFVIDPARTSPFIKSPDSWLPGNTQVIQQYADDHWSEDNQNLYALYPRLGTNGAEIENNRQNSTWWLRDGSFIRMKSLEFGYRFPTKLLNRIKVRNLRVYFSGLNLLTWSPFKMWDPELGGNGFAYPLQKVYNLGINLGI
>NZ_CP049333.1|WP_165305851.1|1526526_1528464_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKTSYSKFLYMAVLIISTVSCKKYLNVTPDNVGTIDYAFRNRNEAENYLFTCYSTLQQMNTPWLDAGFSTSGEIIYPAPNEINDNQGLNPVGFNIMRGTQNAGKPGLNYWDGTEGGQAIFKAIRRCNTMLENIDKPIDLGESEKKRWIAETKFLKAYYHFYLFRMYGPIPIIDVNLPINSSIEDVKVKRAPVDSVVNYMVRLIDEAIPNLPIQIQNPQLELGRITGLIALSVKAQILTTAASPLFNGNPDYIGFSNKDGQPLFNQAKDNTKWDRAAQACSEALNACLANGLRLHTFTPTAAMPANLPKELKDVLTMQTAITEKWELNTELIWGLNPVFGFGLQERFIPRLSAASATNLSSAQGTLSVPIAQQELFYTANGLPIEEDKTWDYRNRYALKTATATDQYHVHNGYETVAAHFKREPRFYAAIAFDGGVWYGNGELNNPTNAFYVQAKGTTSYAGPKDQSHTNITGYWVKKLVNYLTVYGTQMTYENFHFPLMRLSDLYLMYAEVLNEQGKNYSEVLPYIDIVRARANIPAIEDAYTPALSTNPSKYTTQSGLRQIIHQERRIELAFECVPGWDLRRWKELQGVMSKPIQGWNIYNEQSVNYYRPLTLFVPVFSAKNYLWPINSDNFPVNNNLVQNPLW
>NZ_CP049333.1|WP_165305852.1|1528478_1529705_+|DUF4959-domain-containing-protein
MINIKKYTLPLFLLIMVSIISSCKKNNGFNAVISEDTSKPLPVSNVKVDNFTGGANITYNLPNSPNILYVLAKYRVNDNLVRETKSSYYKDTVVVEGFAKEQPYEVTLYTVTRANIMSDPVTVTVNPKIPAYLETRPSLVLSPDFSGVNITGNNPSGKQISIVLLSFNKNTGLMEIEDQFVTKNTKIDHSVFGFNAVERRFAVYVADRWGNLSDTLQTSLTPLFEEAMDKNKFSTLNLSTDTPIDFNWQVQNLWDGRADGSGWHTKFGEPLPYSCSFGIGKTYKLSRFVLFERTGSQYTYKYANPKEFSLWGTNAAIPDNVKLPVRADEGTVIGNWVNLGNFVFPDPPSGNAPANSTAADEDFVKQGVSFRVPFGAPPVKYLRIAVSTVWGREAGAHLMEVTPYGTPE
>NZ_CP049333.1|WP_165305853.1|1529729_1530929_+|hypothetical-protein
MKNNLTTLICCLLALLASCSKQQTDFRDLLGGHEIVYTGLVGQVIEKPGNLRTILTWKKSSDPSIVKYVIFYNQKDSVVVDVTDKKDSVSATITNLEEAVYTFTIYSYDAKGNKSVPKLLNAKIYGPIYQASLLNRPYNGDVPYVAFDNGKVELNFNKPDTVNVTTTVKYTTTANTIKEADLAPTDSILYLNDYKPGTEITYRSFYKPTRNAIDVFSTTSDAVFPQIYFNILCDKSLFRELSLPNDVGTLAESPLRNLWDGSVGPQGYPNIYHSQGNVPLPHTISFDMGKIYNNLSILEETGRNCCHNPDQFEVWGIADISNAATTLPANDAGWKDEAIRKGWTLLLDAVRTDDGSAAKKFELIKNPPPVRYIRIRVKHNANGDTNQSNMSELSFWNGQ
>NZ_CP049333.1|WP_165305854.1|1531007_1533035_+|alpha-galactosidase
MKYFFGILLLLAASMTLSGQTLQIKKNRITFNYNKAKGTYSIGSERQLFINQAVSYLRLANGQKISTDKLTGTRSVTEKPVQDNLGKGIQYTISVKAQQGITLLQHFYFYDTIDGVILEMEVRGKNIASNELVPIWSNASITGLGKSLYQLAVPFDNDTFISYENNVLAMNNKSSSAEVGVVYDKYSGKGLLIGSLDQSVWKSGIAIKGDQGQYTHLAAQAGFTDVNITRDSMAHGAVKGDVIRSPKYLVSYDKDWRIGLENYAKIHRKLSPAYVKSWQGATPVGWNSWGVIQEKLNFQNATGTADYFAKDIPYFRNADGEAFIDLDSFWDNMTPGGMSGDYTQLKQFVLYCDSLGLKPGVYWAPFTDWGHGSGPDRKAEGSQFTFGQLWTKTQKGYHNLDGGRALDPTHPGTLARMDVILGKLVDCGFRMIKVDFLSHAAIESTGFYDKKIQTGMQAYAVGMKHLVDVLQGKMLIYAAISPSLATAQFAHMRRIACDAWKTIDQTQYTLNSVSYGWWQTYLYDFIDADHLVFHDESPEVNKARLLSGVVTGTIILGDDLSKKENWQPKMNQYLQDPEILKIIADGKSFRPAGFVEGKAANTYYYKKIGTALYVAVFNYNTAPAAINIDFKQIGLAPNTTYKAVELFEKAAQEFSAEKSIAFEQAGAKLFKVALF
>NZ_CP049333.1|WP_165305855.1|1533044_1534085_+|GntR-family-transcriptional-regulator
MKKSKEEHFKVLIDRIKRLEALNTLSKHECIVQGVLDAIDANELEVHASLPSVNNLIQYLGYARETFAKAYRDLIAHGVVESKNRKGYFVVSNNTQMKQKVAVLLYAYDTFQDTLVNELRTNLPEEVTVDLFFHHNNMETFEDIFNRIQGRYTVYIVAPIENKDSELLLRSIPASKLLIIDRLVDLGEDYSYVSQEFEEATYAVFQELYPKIKKYKEVIFYFRENTAEPNEIKDAFLRFLKEYKVKGRIEKQYHVGDLKKGKLYFTIHNPELYQMLKEVLQKGWTLGEDLGILSHNDDVIKEIISGGITTFSTSFARIGSQAAKFVLERTLIKEVVPTTLADRNSV

Crispr_ID: NZ_CP049333_3

• CRISPR_ID: NZ_CP049333_3
• CRISPR_location: 1517710-1517806
• CRISPR_type: TypeV-U3
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: c2c10_CAS-V-U3

Consensus repeat of NZ_CP049333_3

Consensus_repeat	Method
GATGTTGATGACCTCAAAAAGTAGGGTATA	CRISPRCasFinder

spacers of NZ_CP049333_3

>3.1|1517740|36|NZ_CP049333|CRISPRCasFinder
CACAATTCCCACCAATAATCACGTAGTTTCTCATTT

CRISPR arrays and Neighbor proteins around NZ_CP049333_3

CRISPR arrays

The CRISPR arrays of NZ_CP049333_3

>merge|NZ_CP049333|3|1517710-1517806|CRISPRCasFinder
GATGTTGATGACCTCAAAAAGTAGGGTATACACAATTCCCACCAATAATCACGTAGTTTCTCATTTGATGTTGATGATCTCAAAGTGTGGGGTATAC

>NZ_CP049333|3|3|1517710-1517806|CRISPRCasFinder
GATGTTGATGACCTCAAAAAGTAGGGTATA	CACAATTCCCACCAATAATCACGTAGTTTCTCATTT
GATGTTGATGATCTCAAAGTGTGGGGTATAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049333.1|WP_165305843.1|1510531_1512076_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl|CDD|185760
NZ_CP049333.1|WP_165305841.1|1505011_1507147_+|DUF5110-domain-containing-protein	unknown	unknown	gnl|CDD|376446
NZ_CP049333.1|WP_165305845.1|1514734_1515238_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NZ_CP049333.1|WP_165305853.1|1529729_1530929_+|hypothetical-protein	unknown	unknown	gnl|CDD|379841
NZ_CP049333.1|WP_165305848.1|1519391_1520486_+|hypothetical-protein	c2c10_CAS-V-U3	-	gnl|CDD|273793
NZ_CP049333.1|WP_165305846.1|1516328_1516838_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP049333.1|WP_108637014.1|1512100_1512868_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP049333.1|WP_165305849.1|1520487_1521057_-|hypothetical-protein	unknown	unknown	gnl|CDD|372659
NZ_CP049333.1|WP_165305838.1|1501827_1502586_+|LamB/YcsF-family-protein	unknown	unknown	gnl|CDD|377121
NZ_CP049333.1|WP_165305842.1|1507420_1510519_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|274948
NZ_CP049333.1|WP_165305840.1|1503881_1505006_+|glycosyl-hydrolase	unknown	unknown	gnl|CDD|369381
NZ_CP049333.1|WP_165305851.1|1526526_1528464_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl|CDD|369630
NZ_CP049333.1|WP_108632869.1|1521278_1521584_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP049333.1|WP_165305850.1|1523327_1526501_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|274948
NZ_CP049333.1|WP_165305852.1|1528478_1529705_+|DUF4959-domain-containing-protein	unknown	unknown	gnl|CDD|379822
NZ_CP049333.1|WP_165305847.1|1518562_1519375_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NZ_CP049333.1|WP_165305854.1|1531007_1533035_+|alpha-galactosidase	unknown	unknown	gnl|CDD|269892
NZ_CP049333.1|WP_165305855.1|1533044_1534085_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|153418
NZ_CP049333.1|WP_165305839.1|1502582_1503752_+|divalent-metal-cation-transporter	unknown	unknown	gnl|CDD|224826
NZ_CP049333.1|WP_165305844.1|1512894_1514358_+|alginate-lyase	unknown	unknown	gnl|CDD|271210

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP049333.1|WP_165305848.1|1519391_1520486_+|hypothetical-protein	c2c10_CAS-V-U3	-	9.9e-54	177.5	12.5

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP049333.1|WP_165305843.1|1510531_1512076_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl|CDD|185760	cd08977, SusD, starch binding outer membrane protein SusD. SusD-like proteins from Bacteroidetes, members of the human distal gut microbiota, are part of the starch utilization system (Sus). Sus is one of the large clusters of glycosyl hydrolases, called polysaccharide utilization loci (PULs), which play an important role in polysaccharide recognition and uptake, and it is needed for growth on amylose, amylopectin, pullulan, and maltooligosaccharides. SusD, together with SusC, a predicted beta-barrel porin, forms the minimum outer-membrane starch-binding complex. The adult human distal gut microbiota is essential for digestion of a large variety of dietary polysaccharides, for which humans lack the necessary glycosyl hydrolases.	1.40785e-34
NZ_CP049333.1|WP_165305841.1|1505011_1507147_+|DUF5110-domain-containing-protein	gnl|CDD|376446	pfam01055, Glyco_hydro_31, Glycosyl hydrolases family 31. Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases.	3.59352e-89
NZ_CP049333.1|WP_165305845.1|1514734_1515238_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.58351e-06
NZ_CP049333.1|WP_165305848.1|1519391_1520486_+|hypothetical-protein	gnl|CDD|273793	TIGR01766, Putative_transposase_MJ0751, transposase, IS605 OrfB family, central region. This model represents a region of a sequence similarity between a family of putative transposases of Thermoanaerobacter tengcongensis, smaller related proteins from Bacillus anthracis, putative transposes described by pfam01385, and other proteins. [Mobile and extrachromosomal element functions, Transposon functions].	0.00203156
NZ_CP049333.1|WP_165305844.1|1512894_1514358_+|alginate-lyase	gnl|CDD|271210	cd14251, PL-6, Polysaccharide Lyase Family 6. Polysaccharide Lyase Family 6 is a family of beta-helical polysaccharide lyases. Members include alginate lyase (EC 4.2.2.3) and chondroitinase B (EC 4.2.2.19). Chondroitinase B is an enzyme that only cleaves the beta-(1,4)-linkage of dermatan sulfate (DS), leading to 4,5-unsaturated dermatan sulfate disaccharides as the product. DS is a highly sulfated, unbranched polysaccharide belonging to a family of glycosaminoglycans (GAGs) composed of alternating hexosamine (gluco- or galactosamine) and uronic acid (D-glucuronic or L-iduronic acid) moieties. DS contains alternating 1,4-beta-D-galactosamine (GalNac) and 1,3-alpha-L-iduronic acid units. The related chondroitin sulfate (CS) contains alternating GalNac and 1,3-beta-D-glucuronic acid units. Alginate lyases (known as either mannuronate (EC 4.2.2.3) or guluronate lyases (EC 4.2.2.11) catalyze the degradation of alginate, a copolymer of alpha-L-guluronate and its C5 epimer beta-D-mannuronate.	1.88279e-154
NZ_CP049333.1|WP_165305849.1|1520487_1521057_-|hypothetical-protein	gnl|CDD|372659	pfam13644, DKNYY, DKNYY family. This family represents a group of proteins found enriched in fusobacteria. These proteins contain many repeats of a DKNXXYY motif. The repeats are spaced at about 35 amino acid residues intervals. These proteins are likely to be associated with the membrane. The specific function of these proteins is unknown.	1.69329e-19
NZ_CP049333.1|WP_165305838.1|1501827_1502586_+|LamB/YcsF-family-protein	gnl|CDD|377121	pfam03746, LamB_YcsF, LamB/YcsF family. This family includes LamB. The lam locus of Aspergillus nidulans consists of two divergently transcribed genes, lamA and lamB, involved in the utilisation of lactams such as 2-pyrrolidinone. Both genes are under the control of the positive regulatory gene amdR and are subject to carbon and nitrogen metabolite repression. The exact molecular function of the proteins in this family is unknown.	3.51543e-148
NZ_CP049333.1|WP_165305842.1|1507420_1510519_+|TonB-dependent-receptor	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0
NZ_CP049333.1|WP_165305840.1|1503881_1505006_+|glycosyl-hydrolase	gnl|CDD|369381	pfam07470, Glyco_hydro_88, Glycosyl Hydrolase Family 88. Unsaturated glucuronyl hydrolase catalyzes the hydrolytic release of unsaturated glucuronic acids from oligosaccharides (EC:3.2.1.-) produced by the reactions of polysaccharide lyases.	7.73875e-50
NZ_CP049333.1|WP_165305851.1|1526526_1528464_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl|CDD|369630	pfam07980, SusD_RagB, SusD family. This domain is found in bacterial cell surface proteins such SusD and SusD-like proteins, as as well RagB, outer membrane surface receptor antigen. Bacteroidetes, one of the two dominant bacterial phyla in the human gut, are Gram-negative saccharolytic microorganisms that utilize a diverse array of glycans. Hence, they express starch-utilization system (Sus) for glycan uptake. SusD has 551 amino acids, and is almost entirely alpha-helical, with 22 alpha-helices, eight of which form 4 tetra-trico peptide repeats (TPRs: helix-turn-helix motifs involved in protein-protein interactions). The four TPRs pack together to create a right-handed super-helix. This is predicted to mediate the formation of SusD and SusC porin complex at the cell surface. The interaction between SusC and TPR1/TPR2 region of SusD is predicted to be of functional importance since it allows SusD to be in position for oligosaccharide capture from other Sus lipoproteins and delivery of these glycans to the SusC porin. The non-TPR containing portion of SusD is where starch binding occurs. The binding site is a shallow surface cavity located on top of TPR1. SusD homologs such as SusD-like proteins have a critical role in carbohydrate acquisition. Both SusD and its homologs, contain about 15-20 residues at the N-terminus that might be a flexible linker region, anchoring the protein to the membrane and the glycan-binding domain. Other homologs to SusD have been examined in Porphyromonas gingivalis such as RagB, an immunodominant outer-membrane surface receptor antigen. Structural characterization of RagB shows substantial similarity with Bacteroides thetaiotaomicron SusD (i.e alpha-helices and TPR regions). Based on this structural similarity, functional studies suggest that, RagB binding of glycans occurs at pockets on the molecular surface that are distinct from those of SusD.	2.50181e-46
NZ_CP049333.1|WP_165305850.1|1523327_1526501_+|TonB-dependent-receptor	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0
NZ_CP049333.1|WP_165305852.1|1528478_1529705_+|DUF4959-domain-containing-protein	gnl|CDD|379822	pfam16323, DUF4959, Domain of unknown function (DUF4959). This family consists of uncharacterized proteins around 400 residues in length and is mainly found in various Bacteroides, Pedobacter and Parabacteroides species. Several proteins are annotated as Galactose-binding like proteins, but the specific function of this protein is unknown.	4.21279e-38
NZ_CP049333.1|WP_165305847.1|1518562_1519375_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	0.00620894
NZ_CP049333.1|WP_165305854.1|1531007_1533035_+|alpha-galactosidase	gnl|CDD|269892	cd14791, GH36, glycosyl hydrolase family 36 (GH36). GH36 enzymes occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-galactosidase, alpha-N-acetylgalactosaminidase, stachyose synthase, and raffinose synthase. All GH36 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH36 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.	2.00903e-10
NZ_CP049333.1|WP_165305855.1|1533044_1534085_+|GntR-family-transcriptional-regulator	gnl|CDD|153418	cd07377, WHTH_GntR, Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators. This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.	3.56462e-10
NZ_CP049333.1|WP_165305839.1|1502582_1503752_+|divalent-metal-cation-transporter	gnl|CDD|224826	COG1914, MntH, Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism].	1.05695e-61
NZ_CP049333.1|WP_165305853.1|1529729_1530929_+|hypothetical-protein	gnl|CDD|379841	pfam16389, DUF4998, Domain of unknown function. This family around 200 residues locates in the N-terminal of some uncharacterized proteins in various Bacteroides and Parabacteroides species. The function of this family remains unknown.	5.42893e-48

Protein sequences

>NZ_CP049333.1|WP_165305846.1|1516328_1516838_-|hypothetical-protein
MYTLLFEVINIKLRLNISNARVVYTLHFEIINILEEVVYPNYLSCVYPTFWDHQHLASADIISIPVVYTPLFEVINMEKGLLYKEDIAVYTLHFEIINIIWISATAGLFSPTSQWQQLSTYKEAILPKNACALYRIKGMMAYLRIVLLQLAIEMPRTVYKLRQIAAILA
>NZ_CP049333.1|WP_165305845.1|1514734_1515238_-|helix-turn-helix-transcriptional-regulator
MGDINEQILEEIGEQLRIQREKIYYTLKDVANMTGLTTNTIAAVERGKGASLNNFILICRALNIQPHTIFKKEIDLTPLYNIPPESKRRIEMTKELDDLVYNSNFFEIPRRVSDIIQQLNANKEQSNKFSVYLSSYCQEGTLEYEKHGNYKEYRKKHSPKPVKKYSK
>NZ_CP049333.1|WP_165305844.1|1512894_1514358_+|alginate-lyase
MNAKKMVFASLSLLLVIGSSCEKPVMINMQLNGVACVQCHTIQSAADLQALSLHPGDTVIMKSGQWTDQELTFAAQGTSQQPIVLMAEQPGTVILKGMSSVSITGKWLVVSGLVFQNGYTSGKNVIDFTSSSSNCRLTNSAIVDYNPPTATTDYRWVSINGSNHRVDHCYLKGKSHQGPTMVVWGTNKTMKHRIDHNFFGKRAELANNGGETIRIGTSDWSMTNAYTTIEDNIFQRCNGEMEIISNKMGADTIRNNFFHESQGTLCLRHGNGSAVYGNYFVGNGNSAAGGIRIIGEDHIVYNNYFQHMSGTGQKAPLVLMDGVPNSPLSGYYQVKRVKVVANTMIKCKQSFDIGSGKGGSSRTLPPTDGHIANNVVSQVATSTMLTFTDQPINFTYQGNIVYDVPTSQQLPAGFTRQNPQYTLTAEGIYEPTGNSPVLGAFVGNYPFAAAADAGAPKLDNKHRDLLKAQNIGPGFMTGLGNSLVINP
>NZ_CP049333.1|WP_108637014.1|1512100_1512868_+|hypothetical-protein
MKRNFNIKWIQVGVMLLTLLTTGCSLFDMELQENYDYEHKTLDPNIGISARKFLENRSYGTPENPTDTAFKWMRMGLEYAGIDLNELEKADRTFIFLHNDAIKIWDVKTKKVTGGLFLDFPIVTGVDGTGKPLTKPAAKWEDYSKEDVRNYFLYLILQGKYNFADLSIDNVKAKTLLPANTVASKGSLLGYLNEGKGFDQEGAMYLKLVNNSDLAPIQINNKTTNRSGGYGVTNGVVHVYGVKGNTTVYPFISLQ
>NZ_CP049333.1|WP_165305843.1|1510531_1512076_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MYKIKILAALLFLGTLGGCNKFLDEKPLADGTLDQHYKNMYDVQAAMAGMYSAFQLEMVGKEQYTEKYLYWGEYRSDNFDRFISYTKDYVDEIVLNSITPSNDFSDWSGLYTTIGRANNNIKYIPQAAQLDSRITMAMQNDYLAQSYALRAMSYFYIVRVWGDAPIWLEPYEDVQQPAERAREPKEKLLKDVIIPDLEKAYSLITKDARSPLWTIGEAGICAIMADVYMWQGDHENAIKWIEKLFLAKSPTNVTYAGLNETNLQDAATWKTIFTNPSSSKETIWSIHWDYLKNGCACMQTSWTSNNKQVIVDEGIWTSWFLPQTTSTPSPDIRPKQTLDVYFGMPSNKRDRFIKWYPTEANPTKADPWPATNQLLPVYLTMYRLSDIYLLYAEALNARGDREKAIKYLNFVRKRAQLPAYDVSAPELATPYALETAILNERQLELFGEGKRWFDLVRTNRVKVVMDPILKRRQEDAGNLEMPGFLDPKNRAYWPLNRNVLNSNSLLVQNPGYTD
>NZ_CP049333.1|WP_165305842.1|1507420_1510519_+|TonB-dependent-receptor
MMKSITKMGCFVLCLFLLMGSMGLPLFAQQNIRISGKVSNSKGDALQGVSVRIKGKSQGTSTDAAGKYQLEAAPTNILVFSQVGMKEEERAIGSQRQIDVQLVESDNALDEIVVTGYGSVAKKRDLTGAISSVSAKKIQERQPINLFDALQGQAAGVLIVNDGGGAPGATGSIQVRGTSTLNGGNGPLYLVDGVINPDGANINPTDIENIEVLKDAASASIYGSRAANGVILITTKRGAEGKPLINVNYNHLFGRLAHYIPVSNSAEVREFRNIQGQNSNIDSLNPSFNADNDLQKLLLGNLAQKKEIKLSIGGGQKNLRYYSSLNYLDDKSIILNSYAKRLQSRINVEYQASSKLRYSNNISFAWQKGNSIPIANTVRVVMDRPAYSLIYYPDGSLTSYVGSKRNPVANALYEQNIDETYSGQFNNQLDYQLTNDLKLTTLFNARLDNLQNTGFSPRFLSANKDQNNGSNEFTKTFSWEFQAFANYNKTFAQDHNVYALLGFSADRRRFDRFHSEYLNSVNEEVLVTFPDYLTSSKTYTSATANATASLFSRVGYNYKSRYLLQASYRRDGSSRFGPSNKWGNFFSGSAAWRFSDENFMKWAKPALQDAKLRYSFGQLGNDKIGDYESYAKVAFGGNYNGVGGASMTPTLGNYLIKWEMTTQNNVGLDLTFLNGRLGFTADYYVKTTTDLLYPRELPKETGYTKLQVNVGSIRTRGMEFVVNARPIVQSNFTWEINGNISFERGKVVKLADGIPFFPGNKWYLEEGGRIGNFYGWRNLGVYAWDESNAYNDNWDKLTLVLDDQGKPLYRDGKPVYTSDGQNYEGPVHHLYAPDGKLKGGDAEWFNNKRDSLINDDDRMILGNPTPDFYFGFMQTFTYKRFSLNVLFNGAIGGEVYNALLQRQNYPSNTGAGSPDMVYNVWRKPGDEAKYPYYPERNNRGNMKTNQNSLYIEDASFIRLASARLAYTFSPNLANKLKMKGLTTYIYGTNLLTWTNYRGYDPEFSTTNPLTPGEDDGRYPRRREFGFGVNVNF
>NZ_CP049333.1|WP_165305841.1|1505011_1507147_+|DUF5110-domain-containing-protein
MEKILIILLLLLCSHAKAQPIQWKEQYPGVWKGTFGQPEKYTLLGAAGIEPRASTLEQLQSTDFPLPKMEVHAELIDGKTYVRMPLTKNEQIYGLGLNFQTVHQRGKILNLHVDHYGGKDNGRTHAPVPFYVSSKGYGVLVNSAQYLTYYVGTAVRKDAKEPAEAKDRNTDKSWNSRPYSDAVEIYIPAAGVEIYVFAGINPLDAIKRYNLFCGGGTLPPRWGLGFTQRIQKLYTAEEVLHEADQFEEHGFPLDFIGLEPGWQSRAYPCTFEWDKGRFPDPASLIRKLATKGIRLNLWTNPYISPEAGISKAIEPYTGSHTVWNGTVPDLNHPEAKKILAKQFMDAQLNIGVSGYKMDEVDGYDYYLWPDMAKFPSGISGIQMRQTYGVLAQKLTDSLYRSQNKRTYGLVRASNAGANNLPYVIYNDYYSHQDFITALVNSGFCGVLWTPEVRGSKTGQEWLRRFQSVVFSPMAMINAWSSGTKPWSFPEVADQVKYYAQLRMELMPYLYSEFAKYHFEGTPPFRAMVLEEGFQGQSKAVLGNQDLETNPYLEAVSREVKDQYMCGEYILVAPLFVGESSRKVLLPKGNWYDFYTGKYVGNGEEIVASPDMDRIPVYVKDGGIIPMMCSRLHAPLSNEKVDLTIRHYGEKEGSYRLYDDDGVSFDYEKGSYAWRRVLVKKNEKGSLSGEISKPQQGKPNTFGRVQFEFMTK
>NZ_CP049333.1|WP_165305840.1|1503881_1505006_+|glycosyl-hydrolase
MRSILSGIAVSLALYAPAQNIDLKNWPEAANPMTVGRLVAQRFVESPHNSFKPPAPPKSITYPEVCTWYGALKFAEISQDKALLDKLTQRFMPFFDTEKHLVPRPWHVDFAVFGTVPLELFRQTKNKTFREMGMRFADAQWSIPIDSPQTVKDSYQKFLDKGLTWQTRYWIDDMYMITMLQSKAFQVTGKRKYIDRAAHEMLVYLDTIQKENGLFYHAPDAPFFWGRGNGWMAAGMSELLSALPKDNLNRPAILASYKKMMASLKKYQREDGLWGQLIDRPESWAETSGSAMFTYALITGVRNGWLDASEYTPIARKAWLALVGYINKEGDIANVCEGTNRKNDYQYYLDRKQKTGDMHGQAPILWCIYALLKK
>NZ_CP049333.1|WP_165305839.1|1502582_1503752_+|divalent-metal-cation-transporter
MKQKNTSALIGAALLMATSAIGPGFLTQTTVFTKSLGASFGFVILVSILIDIGVQLNIWRVIAVSEMRAQDIANKLLPGLGGFISLLIILGGLAFNIGNIAGAGLGLEALFGVHVMTGACISALIAIAVFINKQIGKAMDRFTQFMGAIMILAFIYITLISSPPLGEAVLRTVAPAKIDFVSIITLVGGTVGGYITFAGGHRLIDAGVKGFNALPTVNRSAIMGISVASLVRVCLFLAALGVLSQGLLIEDGNPTASVFRLAAGNFGYRLFGLVMFAASITSIIGSAYTSVSFIKTFSARIAKNENWVIIAFILISTIIFVSVGKPVHLLIIAGAVNGIILPVSLTVMLIAAYKPAIVGVYKQPLILTLIGVTIVVLMAFMSLRVMMDL
>NZ_CP049333.1|WP_165305838.1|1501827_1502586_+|LamB/YcsF-family-protein
MNKQLTVDLNCDLGESFGSWKMGDDEAILPYVSAVNIACGFHAGDPATMMRTVQLALKYKVKIGAHPGFPDLVGFGRREMQLSAREVYELVVYQVGALAACAKVQQTTLQHVKPHGALYNMAARKLELADAIAAAIYDIDPGLILYGLSGSELIRAGRAKGLNVYSEVFADRTYQQDGTLTARSDKHALIHDPERAAEQVVGMIKTGKVISLQGTAVDIRADTICLHGDGEEAVQFAKTINQTLKDKQILIR
>NZ_CP049333.1|WP_165305847.1|1518562_1519375_+|sigma-70-family-RNA-polymerase-sigma-factor
MKLLLLNKDIKTAIEHLHNGHEKGLKFFYQKFYEHFFFRAHRATDDECAGESIAQEAFLRLWLFRENVHSESEVFEFLKVQVKSAIQAFYQKSRNRFHRSLLRLDSIEDYQEFMLGYELEEESEADLLYIEQLELEKKKKMDQINAILPNLNSDQQLFIRLCLKYSFNYERIAYYMGNISDYEVGLHMEKTIEYLRSIIHSEEKMQLMAKPVEFKLNDEMTEEEAEVFRMRYELQYSFDKISEALQLDGGQVRTLFINAHAKIKSAKKTA
>NZ_CP049333.1|WP_165305848.1|1519391_1520486_+|hypothetical-protein
MAADTMVLTRKIQVFVDCDDKEKRSGYFKQLFEWQDLVFRGANMVITHQYVQENLKDLIYLQEDVKIKLADQAKDPEGVLNTSRMNTTYRLLSSYFKGRIPTDILSQINTALIKYFQADRLSYWKGEKSLRNYKKDMPIPFSGRQINLSKDENNRDFKFTLFKIPFRTYLGKDRSDKKVLLQRALVGQIKICSSAIKIVKGKIFLLLALELPKKIQELKDNVIAEASLSIEHPIAVTIGKESFQIGNKEEFTYRRMAIQAARHRLQKAAAFDKGGRGRKRKMKSLEHYNEKEKNYVDTKLHLYSRRLIELCVKAQAGTLLLVNQSNKEEMAKGDEFLLRNWSYYGLIEKIKYKAKMVGINIIIE
>NZ_CP049333.1|WP_165305849.1|1520487_1521057_-|hypothetical-protein
MEKSIAQHIGDNKRPTSQTTFRHDRENDYVSIGNRIFYRDKMVEDVDAGSFKDLGNAYARDNWNAYYRGIKIKDVSPHSFQSLGWGYAKDSWNAYYRGVKIKDVSAPSFKVLDEGYAKDSWNVYYRGNQIKDVSAPSFVLLGDGYSKDSWKVYYFGREIKDATAFTFEYLGKGYAKDSWNEYYRGKKLE
>NZ_CP049333.1|WP_108632869.1|1521278_1521584_+|hypothetical-protein
MSFKEKLENWRTSINRAGSGEELYILLLNYKKFINKNWMDDFGDPGNWKSELNQVISKVRKKVDVADIRNCEDLSSYQDDARQTAHSLNNTLKYHHSLTKG
>NZ_CP049333.1|WP_165305850.1|1523327_1526501_+|TonB-dependent-receptor
MTKGYAQEQLRKLSGTVVDTLGAGIAGVSIVATEGRAGATKTDAQGKFQLDVSTGNVLKFSIVGYQQQFLTVQPNQLTVTIHMKSTSNEIGEVVVTAMGQKQRREAIVGAVTSVRPGDLKVPASNLTNALAGKVAGVIAFQPSGQPGQDNSNFFIRGVTTFGYKKDPLILIDNVEMTSSDLARLQVDDIESFSILKDASSTALYGARGGNGVILVKTKEGKSGRAKIDVRLERSASESVKNLQLADPITYMKLYNEATLTRNPSAVPLYTPNKIMNTQASMEGAPGSNPFVYPAVNWMDMLFKKRTSTERANLNVSGGGGVARYYIAGSYSNDAGILKTDIRNNNNNNVSFKNYQLRSNVNIDLTKSTELVVRLSGNFNEYRGPMTNDPSFATDLYNIAMHTSPVDFPAFYEPDAANAGVQHILFGNNTDATVLPDGSTLPSSSTDVKNINPYAALLRGNRRFSESRMLAQLELNQKLDFITKGLNFRSIFSTNRYARFESELAYAPYFYNVKSYDKASNQYTLNWINNKPDQAREYLNYYAGASTLNTFLYLQGVLDYAADLNENHNISAALIGTQQQQLNANAKTLFTSLPYRNLGLSGRATYAYKSRYFLEFNFGYNGSERFSENHRYGFFPTMGASWIISDEKFYGHFSNVINRMKLRGSYGLVGNDAISDRRFFYLSDVNLNGGNPAYFGINNGYSHNGVTINNYENRDVTWEISRQINLGLELTFLKNIKLITEVYKNYKSDILQDRANIPTTMGLEAGINANIGKVESQGIEFSLDGKHNFSNDLWISSIANFTFAKNKYTQYEEPDYNEKYRLHTGVAINRNYGYIAERLFVDDTEAQNSPTQIFSSNGIAPRGGDIKYRDLNGDGVVDGKDQTWFGNPTVPEIVYGFGLSSGYKNFDLSVFFQGQARVSFVIDPARTSPFIKSPDSWLPGNTQVIQQYADDHWSEDNQNLYALYPRLGTNGAEIENNRQNSTWWLRDGSFIRMKSLEFGYRFPTKLLNRIKVRNLRVYFSGLNLLTWSPFKMWDPELGGNGFAYPLQKVYNLGINLGI
>NZ_CP049333.1|WP_165305851.1|1526526_1528464_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKTSYSKFLYMAVLIISTVSCKKYLNVTPDNVGTIDYAFRNRNEAENYLFTCYSTLQQMNTPWLDAGFSTSGEIIYPAPNEINDNQGLNPVGFNIMRGTQNAGKPGLNYWDGTEGGQAIFKAIRRCNTMLENIDKPIDLGESEKKRWIAETKFLKAYYHFYLFRMYGPIPIIDVNLPINSSIEDVKVKRAPVDSVVNYMVRLIDEAIPNLPIQIQNPQLELGRITGLIALSVKAQILTTAASPLFNGNPDYIGFSNKDGQPLFNQAKDNTKWDRAAQACSEALNACLANGLRLHTFTPTAAMPANLPKELKDVLTMQTAITEKWELNTELIWGLNPVFGFGLQERFIPRLSAASATNLSSAQGTLSVPIAQQELFYTANGLPIEEDKTWDYRNRYALKTATATDQYHVHNGYETVAAHFKREPRFYAAIAFDGGVWYGNGELNNPTNAFYVQAKGTTSYAGPKDQSHTNITGYWVKKLVNYLTVYGTQMTYENFHFPLMRLSDLYLMYAEVLNEQGKNYSEVLPYIDIVRARANIPAIEDAYTPALSTNPSKYTTQSGLRQIIHQERRIELAFECVPGWDLRRWKELQGVMSKPIQGWNIYNEQSVNYYRPLTLFVPVFSAKNYLWPINSDNFPVNNNLVQNPLW
>NZ_CP049333.1|WP_165305852.1|1528478_1529705_+|DUF4959-domain-containing-protein
MINIKKYTLPLFLLIMVSIISSCKKNNGFNAVISEDTSKPLPVSNVKVDNFTGGANITYNLPNSPNILYVLAKYRVNDNLVRETKSSYYKDTVVVEGFAKEQPYEVTLYTVTRANIMSDPVTVTVNPKIPAYLETRPSLVLSPDFSGVNITGNNPSGKQISIVLLSFNKNTGLMEIEDQFVTKNTKIDHSVFGFNAVERRFAVYVADRWGNLSDTLQTSLTPLFEEAMDKNKFSTLNLSTDTPIDFNWQVQNLWDGRADGSGWHTKFGEPLPYSCSFGIGKTYKLSRFVLFERTGSQYTYKYANPKEFSLWGTNAAIPDNVKLPVRADEGTVIGNWVNLGNFVFPDPPSGNAPANSTAADEDFVKQGVSFRVPFGAPPVKYLRIAVSTVWGREAGAHLMEVTPYGTPE
>NZ_CP049333.1|WP_165305853.1|1529729_1530929_+|hypothetical-protein
MKNNLTTLICCLLALLASCSKQQTDFRDLLGGHEIVYTGLVGQVIEKPGNLRTILTWKKSSDPSIVKYVIFYNQKDSVVVDVTDKKDSVSATITNLEEAVYTFTIYSYDAKGNKSVPKLLNAKIYGPIYQASLLNRPYNGDVPYVAFDNGKVELNFNKPDTVNVTTTVKYTTTANTIKEADLAPTDSILYLNDYKPGTEITYRSFYKPTRNAIDVFSTTSDAVFPQIYFNILCDKSLFRELSLPNDVGTLAESPLRNLWDGSVGPQGYPNIYHSQGNVPLPHTISFDMGKIYNNLSILEETGRNCCHNPDQFEVWGIADISNAATTLPANDAGWKDEAIRKGWTLLLDAVRTDDGSAAKKFELIKNPPPVRYIRIRVKHNANGDTNQSNMSELSFWNGQ
>NZ_CP049333.1|WP_165305854.1|1531007_1533035_+|alpha-galactosidase
MKYFFGILLLLAASMTLSGQTLQIKKNRITFNYNKAKGTYSIGSERQLFINQAVSYLRLANGQKISTDKLTGTRSVTEKPVQDNLGKGIQYTISVKAQQGITLLQHFYFYDTIDGVILEMEVRGKNIASNELVPIWSNASITGLGKSLYQLAVPFDNDTFISYENNVLAMNNKSSSAEVGVVYDKYSGKGLLIGSLDQSVWKSGIAIKGDQGQYTHLAAQAGFTDVNITRDSMAHGAVKGDVIRSPKYLVSYDKDWRIGLENYAKIHRKLSPAYVKSWQGATPVGWNSWGVIQEKLNFQNATGTADYFAKDIPYFRNADGEAFIDLDSFWDNMTPGGMSGDYTQLKQFVLYCDSLGLKPGVYWAPFTDWGHGSGPDRKAEGSQFTFGQLWTKTQKGYHNLDGGRALDPTHPGTLARMDVILGKLVDCGFRMIKVDFLSHAAIESTGFYDKKIQTGMQAYAVGMKHLVDVLQGKMLIYAAISPSLATAQFAHMRRIACDAWKTIDQTQYTLNSVSYGWWQTYLYDFIDADHLVFHDESPEVNKARLLSGVVTGTIILGDDLSKKENWQPKMNQYLQDPEILKIIADGKSFRPAGFVEGKAANTYYYKKIGTALYVAVFNYNTAPAAINIDFKQIGLAPNTTYKAVELFEKAAQEFSAEKSIAFEQAGAKLFKVALF
>NZ_CP049333.1|WP_165305855.1|1533044_1534085_+|GntR-family-transcriptional-regulator
MKKSKEEHFKVLIDRIKRLEALNTLSKHECIVQGVLDAIDANELEVHASLPSVNNLIQYLGYARETFAKAYRDLIAHGVVESKNRKGYFVVSNNTQMKQKVAVLLYAYDTFQDTLVNELRTNLPEEVTVDLFFHHNNMETFEDIFNRIQGRYTVYIVAPIENKDSELLLRSIPASKLLIIDRLVDLGEDYSYVSQEFEEATYAVFQELYPKIKKYKEVIFYFRENTAEPNEIKDAFLRFLKEYKVKGRIEKQYHVGDLKKGKLYFTIHNPELYQMLKEVLQKGWTLGEDLGILSHNDDVIKEIISGGITTFSTSFARIGSQAAKFVLERTLIKEVVPTTLADRNSV

Crispr_ID: NZ_CP049333_4

• CRISPR_ID: NZ_CP049333_4
• CRISPR_location: 1517992-1518351
• CRISPR_type: TypeV-U3
• Repeat_type: NA
• Spacer_info: 5 spacers
• Cas_protein_info: c2c10_CAS-V-U3

Consensus repeat of NZ_CP049333_4

Consensus_repeat	Method
GATGTTGATGATCTCAAAAAGTAGGGTATACACAAC	PILER-CR
GATGTTGATGACCTCAAAAAGTAGGGTATA	CRISPRCasFinder
CTCAAAANGTAGGGTATANACAAC	CRT
GATGTTGATGACCTCAAAAAGTAGGGTATA	CRISPRCasFinder

spacers of NZ_CP049333_4

>4.1|1518028|26|NZ_CP049333|PILER-CR
GGTTAATAATAAATTTAATTGCTCTA
>4.2|1518090|30|NZ_CP049333|PILER-CR
TGTCCCTGTAGTATGTATTAAGGAATTCTG
>4.3|1518156|30|NZ_CP049333|PILER-CR
TCCAAGCTTTTGAAACCAAATATTTTCTTT
>4.4|1518222|30|NZ_CP049333|PILER-CR
ATTATAAATTCTATCAAATCTTTTTGAGAA
>4.5|1518288|29|NZ_CP049333|PILER-CR
GAGTTTAGAAATCTTAAGATAAACTGTCC
>4.6|1518022|32|NZ_CP049333|CRISPRCasFinder
TACAGCGGTTAATAATAAATTTAATTGCTCTA
>4.7|1518084|36|NZ_CP049333|CRISPRCasFinder
CACAACTGTCCCTGTAGTATGTATTAAGGAATTCTG
>4.8|1518028|38|NZ_CP049333|CRT
GGTTAATAATAAATTTAATTGCTCTAGATGTTGACGAT
>4.9|1518090|42|NZ_CP049333|CRT
TGTCCCTGTAGTATGTATTAAGGAATTCTGGATGTTGATGAT
>4.10|1518156|41|NZ_CP049333|CRT
TCCAAGCTTTTGAAACCAAATATTTTCTTTGATGTTGATGA
>4.11|1518221|42|NZ_CP049333|CRT
ATTATAAATTCTATCAAATCTTTTTGAGAAGATGTTGATGAC
>4.12|1518287|41|NZ_CP049333|CRT
GAGTTTAGAAATCTTAAGATAAACTGTCCGATGTTGATGAT
>4.13|1518281|35|NZ_CP049333|CRISPRCasFinder
CACAACGAGTTTAGAAATCTTAAGATAAACTGTCC

CRISPR arrays and Neighbor proteins around NZ_CP049333_4

CRISPR arrays

The CRISPR arrays of NZ_CP049333_4

>merge|NZ_CP049333|4|1517992-1518351|PILER-CR,CRISPRCasFinder,CRT,CRISPRCasFinder
GATGTTGATGACCTCAAAAAGTAGGGTATATACAGCGGTTAATAATAAATTTAATTGCTCTAGATGTTGACGATCTCAAAAAGTAGGGTATACACAACTGTCCCTGTAGTATGTATTAAGGAATTCTGGATGTTGATGATCTCAAAAAGTAGGGTATACACAACTCCAAGCTTTTGAAACCAAATATTTTCTTTGATGTTGATGATCTAAAATGTAGGGTATACACAACATTATAAATTCTATCAAATCTTTTTGAGAAGATGTTGATGACCTCAAAAAGTAGGGTATACACAACGAGTTTAGAAATCTTAAGATAAACTGTCCGATGTTGATGATCTCAAAATGTAGGGTATATACAAT

>NZ_CP049333|4|2|1517992-1518351|PILER-CR
GATGTTGATGACCTCAAAAAGTAGGGTATATACAGC	GGTTAATAATAAATTTAATTGCTCTA
GATGTTGACGATCTCAAAAAGTAGGGTATACACAAC	TGTCCCTGTAGTATGTATTAAGGAATTCTG
GATGTTGATGATCTCAAAAAGTAGGGTATACACAAC	TCCAAGCTTTTGAAACCAAATATTTTCTTT
GATGTTGATGATCTAAAATGTAGGGTATACACAACA	TTATAAATTCTATCAAATCTTTTTGAGAAG
ATGTTGATGACCTCAAAAAGTAGGGTATACACAACG	AGTTTAGAAATCTTAAGATAAACTGTCCG
ATGTTGATGATCTCAAAATGTAGGGTATATACAAT

>NZ_CP049333|4|4|1517992-1518150|CRISPRCasFinder
GATGTTGATGACCTCAAAAAGTAGGGTATA	TACAGCGGTTAATAATAAATTTAATTGCTCTA
GATGTTGACGATCTCAAAAAGTAGGGTATA	CACAACTGTCCCTGTAGTATGTATTAAGGAATTCTG
GATGTTGATGATCTCAAAAAGTAGGGTATACACAACTCCAAGCTTTTGAAACCAAATATTTTCTTTGATGTTGATGATCTAAAATGTAGGGTATACACAACATTATAAATTCTATCAAATCTTTTTGAGAAGATGTTGATGACCTCAAAAAGTAGGGTATA	CACAACGAGTTTAGAAATCTTAAGATAAACTGTCC


>NZ_CP049333|4|3|1518004-1518351|CRT
CTCAAAAAGTAGGGTATATACAGC	GGTTAATAATAAATTTAATTGCTCTAGATGTTGACGAT
CTCAAAAAGTAGGGTATACACAAC	TGTCCCTGTAGTATGTATTAAGGAATTCTGGATGTTGATGAT
CTCAAAAAGTAGGGTATACACAAC	TCCAAGCTTTTGAAACCAAATATTTTCTTTGATGTTGATGA
TCTAAAATGTAGGGTATACACAAC	ATTATAAATTCTATCAAATCTTTTTGAGAAGATGTTGATGAC
CTCAAAAAGTAGGGTATACACAAC	GAGTTTAGAAATCTTAAGATAAACTGTCCGATGTTGATGAT
CTCAAAATGTAGGGTATATACAAT

>NZ_CP049333|4|5|1518251-1518345|CRISPRCasFinder
	TACAGCGGTTAATAATAAATTTAATTGCTCTA
GATGTTGACGATCTCAAAAAGTAGGGTATA	CACAACTGTCCCTGTAGTATGTATTAAGGAATTCTG
GATGTTGATGATCTCAAAAAGTAGGGTATACACAACTCCAAGCTTTTGAAACCAAATATTTTCTTTGATGTTGATGATCTAAAATGTAGGGTATACACAACATTATAAATTCTATCAAATCTTTTTGAGAAGATGTTGATGACCTCAAAAAGTAGGGTATA	CACAACGAGTTTAGAAATCTTAAGATAAACTGTCC
GATGTTGATGATCTCAAAATGTAGGGTATA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049333.1|WP_165305843.1|1510531_1512076_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl|CDD|185760
NZ_CP049333.1|WP_165305841.1|1505011_1507147_+|DUF5110-domain-containing-protein	unknown	unknown	gnl|CDD|376446
NZ_CP049333.1|WP_165305845.1|1514734_1515238_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NZ_CP049333.1|WP_165305853.1|1529729_1530929_+|hypothetical-protein	unknown	unknown	gnl|CDD|379841
NZ_CP049333.1|WP_165305848.1|1519391_1520486_+|hypothetical-protein	c2c10_CAS-V-U3	-	gnl|CDD|273793
NZ_CP049333.1|WP_165305846.1|1516328_1516838_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP049333.1|WP_108637014.1|1512100_1512868_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP049333.1|WP_165305849.1|1520487_1521057_-|hypothetical-protein	unknown	unknown	gnl|CDD|372659
NZ_CP049333.1|WP_165305838.1|1501827_1502586_+|LamB/YcsF-family-protein	unknown	unknown	gnl|CDD|377121
NZ_CP049333.1|WP_165305842.1|1507420_1510519_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|274948
NZ_CP049333.1|WP_165305840.1|1503881_1505006_+|glycosyl-hydrolase	unknown	unknown	gnl|CDD|369381
NZ_CP049333.1|WP_165305851.1|1526526_1528464_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl|CDD|369630
NZ_CP049333.1|WP_108632869.1|1521278_1521584_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP049333.1|WP_165305850.1|1523327_1526501_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|274948
NZ_CP049333.1|WP_165305852.1|1528478_1529705_+|DUF4959-domain-containing-protein	unknown	unknown	gnl|CDD|379822
NZ_CP049333.1|WP_165305847.1|1518562_1519375_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NZ_CP049333.1|WP_165305854.1|1531007_1533035_+|alpha-galactosidase	unknown	unknown	gnl|CDD|269892
NZ_CP049333.1|WP_165305855.1|1533044_1534085_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|153418
NZ_CP049333.1|WP_165305839.1|1502582_1503752_+|divalent-metal-cation-transporter	unknown	unknown	gnl|CDD|224826
NZ_CP049333.1|WP_165305844.1|1512894_1514358_+|alginate-lyase	unknown	unknown	gnl|CDD|271210

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP049333.1|WP_165305848.1|1519391_1520486_+|hypothetical-protein	c2c10_CAS-V-U3	-	9.9e-54	177.5	12.5

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP049333.1|WP_165305843.1|1510531_1512076_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl|CDD|185760	cd08977, SusD, starch binding outer membrane protein SusD. SusD-like proteins from Bacteroidetes, members of the human distal gut microbiota, are part of the starch utilization system (Sus). Sus is one of the large clusters of glycosyl hydrolases, called polysaccharide utilization loci (PULs), which play an important role in polysaccharide recognition and uptake, and it is needed for growth on amylose, amylopectin, pullulan, and maltooligosaccharides. SusD, together with SusC, a predicted beta-barrel porin, forms the minimum outer-membrane starch-binding complex. The adult human distal gut microbiota is essential for digestion of a large variety of dietary polysaccharides, for which humans lack the necessary glycosyl hydrolases.	1.40785e-34
NZ_CP049333.1|WP_165305841.1|1505011_1507147_+|DUF5110-domain-containing-protein	gnl|CDD|376446	pfam01055, Glyco_hydro_31, Glycosyl hydrolases family 31. Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases.	3.59352e-89
NZ_CP049333.1|WP_165305845.1|1514734_1515238_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.58351e-06
NZ_CP049333.1|WP_165305848.1|1519391_1520486_+|hypothetical-protein	gnl|CDD|273793	TIGR01766, Putative_transposase_MJ0751, transposase, IS605 OrfB family, central region. This model represents a region of a sequence similarity between a family of putative transposases of Thermoanaerobacter tengcongensis, smaller related proteins from Bacillus anthracis, putative transposes described by pfam01385, and other proteins. [Mobile and extrachromosomal element functions, Transposon functions].	0.00203156
NZ_CP049333.1|WP_165305844.1|1512894_1514358_+|alginate-lyase	gnl|CDD|271210	cd14251, PL-6, Polysaccharide Lyase Family 6. Polysaccharide Lyase Family 6 is a family of beta-helical polysaccharide lyases. Members include alginate lyase (EC 4.2.2.3) and chondroitinase B (EC 4.2.2.19). Chondroitinase B is an enzyme that only cleaves the beta-(1,4)-linkage of dermatan sulfate (DS), leading to 4,5-unsaturated dermatan sulfate disaccharides as the product. DS is a highly sulfated, unbranched polysaccharide belonging to a family of glycosaminoglycans (GAGs) composed of alternating hexosamine (gluco- or galactosamine) and uronic acid (D-glucuronic or L-iduronic acid) moieties. DS contains alternating 1,4-beta-D-galactosamine (GalNac) and 1,3-alpha-L-iduronic acid units. The related chondroitin sulfate (CS) contains alternating GalNac and 1,3-beta-D-glucuronic acid units. Alginate lyases (known as either mannuronate (EC 4.2.2.3) or guluronate lyases (EC 4.2.2.11) catalyze the degradation of alginate, a copolymer of alpha-L-guluronate and its C5 epimer beta-D-mannuronate.	1.88279e-154
NZ_CP049333.1|WP_165305849.1|1520487_1521057_-|hypothetical-protein	gnl|CDD|372659	pfam13644, DKNYY, DKNYY family. This family represents a group of proteins found enriched in fusobacteria. These proteins contain many repeats of a DKNXXYY motif. The repeats are spaced at about 35 amino acid residues intervals. These proteins are likely to be associated with the membrane. The specific function of these proteins is unknown.	1.69329e-19
NZ_CP049333.1|WP_165305838.1|1501827_1502586_+|LamB/YcsF-family-protein	gnl|CDD|377121	pfam03746, LamB_YcsF, LamB/YcsF family. This family includes LamB. The lam locus of Aspergillus nidulans consists of two divergently transcribed genes, lamA and lamB, involved in the utilisation of lactams such as 2-pyrrolidinone. Both genes are under the control of the positive regulatory gene amdR and are subject to carbon and nitrogen metabolite repression. The exact molecular function of the proteins in this family is unknown.	3.51543e-148
NZ_CP049333.1|WP_165305842.1|1507420_1510519_+|TonB-dependent-receptor	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0
NZ_CP049333.1|WP_165305840.1|1503881_1505006_+|glycosyl-hydrolase	gnl|CDD|369381	pfam07470, Glyco_hydro_88, Glycosyl Hydrolase Family 88. Unsaturated glucuronyl hydrolase catalyzes the hydrolytic release of unsaturated glucuronic acids from oligosaccharides (EC:3.2.1.-) produced by the reactions of polysaccharide lyases.	7.73875e-50
NZ_CP049333.1|WP_165305851.1|1526526_1528464_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl|CDD|369630	pfam07980, SusD_RagB, SusD family. This domain is found in bacterial cell surface proteins such SusD and SusD-like proteins, as as well RagB, outer membrane surface receptor antigen. Bacteroidetes, one of the two dominant bacterial phyla in the human gut, are Gram-negative saccharolytic microorganisms that utilize a diverse array of glycans. Hence, they express starch-utilization system (Sus) for glycan uptake. SusD has 551 amino acids, and is almost entirely alpha-helical, with 22 alpha-helices, eight of which form 4 tetra-trico peptide repeats (TPRs: helix-turn-helix motifs involved in protein-protein interactions). The four TPRs pack together to create a right-handed super-helix. This is predicted to mediate the formation of SusD and SusC porin complex at the cell surface. The interaction between SusC and TPR1/TPR2 region of SusD is predicted to be of functional importance since it allows SusD to be in position for oligosaccharide capture from other Sus lipoproteins and delivery of these glycans to the SusC porin. The non-TPR containing portion of SusD is where starch binding occurs. The binding site is a shallow surface cavity located on top of TPR1. SusD homologs such as SusD-like proteins have a critical role in carbohydrate acquisition. Both SusD and its homologs, contain about 15-20 residues at the N-terminus that might be a flexible linker region, anchoring the protein to the membrane and the glycan-binding domain. Other homologs to SusD have been examined in Porphyromonas gingivalis such as RagB, an immunodominant outer-membrane surface receptor antigen. Structural characterization of RagB shows substantial similarity with Bacteroides thetaiotaomicron SusD (i.e alpha-helices and TPR regions). Based on this structural similarity, functional studies suggest that, RagB binding of glycans occurs at pockets on the molecular surface that are distinct from those of SusD.	2.50181e-46
NZ_CP049333.1|WP_165305850.1|1523327_1526501_+|TonB-dependent-receptor	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0
NZ_CP049333.1|WP_165305852.1|1528478_1529705_+|DUF4959-domain-containing-protein	gnl|CDD|379822	pfam16323, DUF4959, Domain of unknown function (DUF4959). This family consists of uncharacterized proteins around 400 residues in length and is mainly found in various Bacteroides, Pedobacter and Parabacteroides species. Several proteins are annotated as Galactose-binding like proteins, but the specific function of this protein is unknown.	4.21279e-38
NZ_CP049333.1|WP_165305847.1|1518562_1519375_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	0.00620894
NZ_CP049333.1|WP_165305854.1|1531007_1533035_+|alpha-galactosidase	gnl|CDD|269892	cd14791, GH36, glycosyl hydrolase family 36 (GH36). GH36 enzymes occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-galactosidase, alpha-N-acetylgalactosaminidase, stachyose synthase, and raffinose synthase. All GH36 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH36 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.	2.00903e-10
NZ_CP049333.1|WP_165305855.1|1533044_1534085_+|GntR-family-transcriptional-regulator	gnl|CDD|153418	cd07377, WHTH_GntR, Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators. This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.	3.56462e-10
NZ_CP049333.1|WP_165305839.1|1502582_1503752_+|divalent-metal-cation-transporter	gnl|CDD|224826	COG1914, MntH, Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism].	1.05695e-61
NZ_CP049333.1|WP_165305853.1|1529729_1530929_+|hypothetical-protein	gnl|CDD|379841	pfam16389, DUF4998, Domain of unknown function. This family around 200 residues locates in the N-terminal of some uncharacterized proteins in various Bacteroides and Parabacteroides species. The function of this family remains unknown.	5.42893e-48

Protein sequences

>NZ_CP049333.1|WP_165305846.1|1516328_1516838_-|hypothetical-protein
MYTLLFEVINIKLRLNISNARVVYTLHFEIINILEEVVYPNYLSCVYPTFWDHQHLASADIISIPVVYTPLFEVINMEKGLLYKEDIAVYTLHFEIINIIWISATAGLFSPTSQWQQLSTYKEAILPKNACALYRIKGMMAYLRIVLLQLAIEMPRTVYKLRQIAAILA
>NZ_CP049333.1|WP_165305845.1|1514734_1515238_-|helix-turn-helix-transcriptional-regulator
MGDINEQILEEIGEQLRIQREKIYYTLKDVANMTGLTTNTIAAVERGKGASLNNFILICRALNIQPHTIFKKEIDLTPLYNIPPESKRRIEMTKELDDLVYNSNFFEIPRRVSDIIQQLNANKEQSNKFSVYLSSYCQEGTLEYEKHGNYKEYRKKHSPKPVKKYSK
>NZ_CP049333.1|WP_165305844.1|1512894_1514358_+|alginate-lyase
MNAKKMVFASLSLLLVIGSSCEKPVMINMQLNGVACVQCHTIQSAADLQALSLHPGDTVIMKSGQWTDQELTFAAQGTSQQPIVLMAEQPGTVILKGMSSVSITGKWLVVSGLVFQNGYTSGKNVIDFTSSSSNCRLTNSAIVDYNPPTATTDYRWVSINGSNHRVDHCYLKGKSHQGPTMVVWGTNKTMKHRIDHNFFGKRAELANNGGETIRIGTSDWSMTNAYTTIEDNIFQRCNGEMEIISNKMGADTIRNNFFHESQGTLCLRHGNGSAVYGNYFVGNGNSAAGGIRIIGEDHIVYNNYFQHMSGTGQKAPLVLMDGVPNSPLSGYYQVKRVKVVANTMIKCKQSFDIGSGKGGSSRTLPPTDGHIANNVVSQVATSTMLTFTDQPINFTYQGNIVYDVPTSQQLPAGFTRQNPQYTLTAEGIYEPTGNSPVLGAFVGNYPFAAAADAGAPKLDNKHRDLLKAQNIGPGFMTGLGNSLVINP
>NZ_CP049333.1|WP_108637014.1|1512100_1512868_+|hypothetical-protein
MKRNFNIKWIQVGVMLLTLLTTGCSLFDMELQENYDYEHKTLDPNIGISARKFLENRSYGTPENPTDTAFKWMRMGLEYAGIDLNELEKADRTFIFLHNDAIKIWDVKTKKVTGGLFLDFPIVTGVDGTGKPLTKPAAKWEDYSKEDVRNYFLYLILQGKYNFADLSIDNVKAKTLLPANTVASKGSLLGYLNEGKGFDQEGAMYLKLVNNSDLAPIQINNKTTNRSGGYGVTNGVVHVYGVKGNTTVYPFISLQ
>NZ_CP049333.1|WP_165305843.1|1510531_1512076_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MYKIKILAALLFLGTLGGCNKFLDEKPLADGTLDQHYKNMYDVQAAMAGMYSAFQLEMVGKEQYTEKYLYWGEYRSDNFDRFISYTKDYVDEIVLNSITPSNDFSDWSGLYTTIGRANNNIKYIPQAAQLDSRITMAMQNDYLAQSYALRAMSYFYIVRVWGDAPIWLEPYEDVQQPAERAREPKEKLLKDVIIPDLEKAYSLITKDARSPLWTIGEAGICAIMADVYMWQGDHENAIKWIEKLFLAKSPTNVTYAGLNETNLQDAATWKTIFTNPSSSKETIWSIHWDYLKNGCACMQTSWTSNNKQVIVDEGIWTSWFLPQTTSTPSPDIRPKQTLDVYFGMPSNKRDRFIKWYPTEANPTKADPWPATNQLLPVYLTMYRLSDIYLLYAEALNARGDREKAIKYLNFVRKRAQLPAYDVSAPELATPYALETAILNERQLELFGEGKRWFDLVRTNRVKVVMDPILKRRQEDAGNLEMPGFLDPKNRAYWPLNRNVLNSNSLLVQNPGYTD
>NZ_CP049333.1|WP_165305842.1|1507420_1510519_+|TonB-dependent-receptor
MMKSITKMGCFVLCLFLLMGSMGLPLFAQQNIRISGKVSNSKGDALQGVSVRIKGKSQGTSTDAAGKYQLEAAPTNILVFSQVGMKEEERAIGSQRQIDVQLVESDNALDEIVVTGYGSVAKKRDLTGAISSVSAKKIQERQPINLFDALQGQAAGVLIVNDGGGAPGATGSIQVRGTSTLNGGNGPLYLVDGVINPDGANINPTDIENIEVLKDAASASIYGSRAANGVILITTKRGAEGKPLINVNYNHLFGRLAHYIPVSNSAEVREFRNIQGQNSNIDSLNPSFNADNDLQKLLLGNLAQKKEIKLSIGGGQKNLRYYSSLNYLDDKSIILNSYAKRLQSRINVEYQASSKLRYSNNISFAWQKGNSIPIANTVRVVMDRPAYSLIYYPDGSLTSYVGSKRNPVANALYEQNIDETYSGQFNNQLDYQLTNDLKLTTLFNARLDNLQNTGFSPRFLSANKDQNNGSNEFTKTFSWEFQAFANYNKTFAQDHNVYALLGFSADRRRFDRFHSEYLNSVNEEVLVTFPDYLTSSKTYTSATANATASLFSRVGYNYKSRYLLQASYRRDGSSRFGPSNKWGNFFSGSAAWRFSDENFMKWAKPALQDAKLRYSFGQLGNDKIGDYESYAKVAFGGNYNGVGGASMTPTLGNYLIKWEMTTQNNVGLDLTFLNGRLGFTADYYVKTTTDLLYPRELPKETGYTKLQVNVGSIRTRGMEFVVNARPIVQSNFTWEINGNISFERGKVVKLADGIPFFPGNKWYLEEGGRIGNFYGWRNLGVYAWDESNAYNDNWDKLTLVLDDQGKPLYRDGKPVYTSDGQNYEGPVHHLYAPDGKLKGGDAEWFNNKRDSLINDDDRMILGNPTPDFYFGFMQTFTYKRFSLNVLFNGAIGGEVYNALLQRQNYPSNTGAGSPDMVYNVWRKPGDEAKYPYYPERNNRGNMKTNQNSLYIEDASFIRLASARLAYTFSPNLANKLKMKGLTTYIYGTNLLTWTNYRGYDPEFSTTNPLTPGEDDGRYPRRREFGFGVNVNF
>NZ_CP049333.1|WP_165305841.1|1505011_1507147_+|DUF5110-domain-containing-protein
MEKILIILLLLLCSHAKAQPIQWKEQYPGVWKGTFGQPEKYTLLGAAGIEPRASTLEQLQSTDFPLPKMEVHAELIDGKTYVRMPLTKNEQIYGLGLNFQTVHQRGKILNLHVDHYGGKDNGRTHAPVPFYVSSKGYGVLVNSAQYLTYYVGTAVRKDAKEPAEAKDRNTDKSWNSRPYSDAVEIYIPAAGVEIYVFAGINPLDAIKRYNLFCGGGTLPPRWGLGFTQRIQKLYTAEEVLHEADQFEEHGFPLDFIGLEPGWQSRAYPCTFEWDKGRFPDPASLIRKLATKGIRLNLWTNPYISPEAGISKAIEPYTGSHTVWNGTVPDLNHPEAKKILAKQFMDAQLNIGVSGYKMDEVDGYDYYLWPDMAKFPSGISGIQMRQTYGVLAQKLTDSLYRSQNKRTYGLVRASNAGANNLPYVIYNDYYSHQDFITALVNSGFCGVLWTPEVRGSKTGQEWLRRFQSVVFSPMAMINAWSSGTKPWSFPEVADQVKYYAQLRMELMPYLYSEFAKYHFEGTPPFRAMVLEEGFQGQSKAVLGNQDLETNPYLEAVSREVKDQYMCGEYILVAPLFVGESSRKVLLPKGNWYDFYTGKYVGNGEEIVASPDMDRIPVYVKDGGIIPMMCSRLHAPLSNEKVDLTIRHYGEKEGSYRLYDDDGVSFDYEKGSYAWRRVLVKKNEKGSLSGEISKPQQGKPNTFGRVQFEFMTK
>NZ_CP049333.1|WP_165305840.1|1503881_1505006_+|glycosyl-hydrolase
MRSILSGIAVSLALYAPAQNIDLKNWPEAANPMTVGRLVAQRFVESPHNSFKPPAPPKSITYPEVCTWYGALKFAEISQDKALLDKLTQRFMPFFDTEKHLVPRPWHVDFAVFGTVPLELFRQTKNKTFREMGMRFADAQWSIPIDSPQTVKDSYQKFLDKGLTWQTRYWIDDMYMITMLQSKAFQVTGKRKYIDRAAHEMLVYLDTIQKENGLFYHAPDAPFFWGRGNGWMAAGMSELLSALPKDNLNRPAILASYKKMMASLKKYQREDGLWGQLIDRPESWAETSGSAMFTYALITGVRNGWLDASEYTPIARKAWLALVGYINKEGDIANVCEGTNRKNDYQYYLDRKQKTGDMHGQAPILWCIYALLKK
>NZ_CP049333.1|WP_165305839.1|1502582_1503752_+|divalent-metal-cation-transporter
MKQKNTSALIGAALLMATSAIGPGFLTQTTVFTKSLGASFGFVILVSILIDIGVQLNIWRVIAVSEMRAQDIANKLLPGLGGFISLLIILGGLAFNIGNIAGAGLGLEALFGVHVMTGACISALIAIAVFINKQIGKAMDRFTQFMGAIMILAFIYITLISSPPLGEAVLRTVAPAKIDFVSIITLVGGTVGGYITFAGGHRLIDAGVKGFNALPTVNRSAIMGISVASLVRVCLFLAALGVLSQGLLIEDGNPTASVFRLAAGNFGYRLFGLVMFAASITSIIGSAYTSVSFIKTFSARIAKNENWVIIAFILISTIIFVSVGKPVHLLIIAGAVNGIILPVSLTVMLIAAYKPAIVGVYKQPLILTLIGVTIVVLMAFMSLRVMMDL
>NZ_CP049333.1|WP_165305838.1|1501827_1502586_+|LamB/YcsF-family-protein
MNKQLTVDLNCDLGESFGSWKMGDDEAILPYVSAVNIACGFHAGDPATMMRTVQLALKYKVKIGAHPGFPDLVGFGRREMQLSAREVYELVVYQVGALAACAKVQQTTLQHVKPHGALYNMAARKLELADAIAAAIYDIDPGLILYGLSGSELIRAGRAKGLNVYSEVFADRTYQQDGTLTARSDKHALIHDPERAAEQVVGMIKTGKVISLQGTAVDIRADTICLHGDGEEAVQFAKTINQTLKDKQILIR
>NZ_CP049333.1|WP_165305847.1|1518562_1519375_+|sigma-70-family-RNA-polymerase-sigma-factor
MKLLLLNKDIKTAIEHLHNGHEKGLKFFYQKFYEHFFFRAHRATDDECAGESIAQEAFLRLWLFRENVHSESEVFEFLKVQVKSAIQAFYQKSRNRFHRSLLRLDSIEDYQEFMLGYELEEESEADLLYIEQLELEKKKKMDQINAILPNLNSDQQLFIRLCLKYSFNYERIAYYMGNISDYEVGLHMEKTIEYLRSIIHSEEKMQLMAKPVEFKLNDEMTEEEAEVFRMRYELQYSFDKISEALQLDGGQVRTLFINAHAKIKSAKKTA
>NZ_CP049333.1|WP_165305848.1|1519391_1520486_+|hypothetical-protein
MAADTMVLTRKIQVFVDCDDKEKRSGYFKQLFEWQDLVFRGANMVITHQYVQENLKDLIYLQEDVKIKLADQAKDPEGVLNTSRMNTTYRLLSSYFKGRIPTDILSQINTALIKYFQADRLSYWKGEKSLRNYKKDMPIPFSGRQINLSKDENNRDFKFTLFKIPFRTYLGKDRSDKKVLLQRALVGQIKICSSAIKIVKGKIFLLLALELPKKIQELKDNVIAEASLSIEHPIAVTIGKESFQIGNKEEFTYRRMAIQAARHRLQKAAAFDKGGRGRKRKMKSLEHYNEKEKNYVDTKLHLYSRRLIELCVKAQAGTLLLVNQSNKEEMAKGDEFLLRNWSYYGLIEKIKYKAKMVGINIIIE
>NZ_CP049333.1|WP_165305849.1|1520487_1521057_-|hypothetical-protein
MEKSIAQHIGDNKRPTSQTTFRHDRENDYVSIGNRIFYRDKMVEDVDAGSFKDLGNAYARDNWNAYYRGIKIKDVSPHSFQSLGWGYAKDSWNAYYRGVKIKDVSAPSFKVLDEGYAKDSWNVYYRGNQIKDVSAPSFVLLGDGYSKDSWKVYYFGREIKDATAFTFEYLGKGYAKDSWNEYYRGKKLE
>NZ_CP049333.1|WP_108632869.1|1521278_1521584_+|hypothetical-protein
MSFKEKLENWRTSINRAGSGEELYILLLNYKKFINKNWMDDFGDPGNWKSELNQVISKVRKKVDVADIRNCEDLSSYQDDARQTAHSLNNTLKYHHSLTKG
>NZ_CP049333.1|WP_165305850.1|1523327_1526501_+|TonB-dependent-receptor
MTKGYAQEQLRKLSGTVVDTLGAGIAGVSIVATEGRAGATKTDAQGKFQLDVSTGNVLKFSIVGYQQQFLTVQPNQLTVTIHMKSTSNEIGEVVVTAMGQKQRREAIVGAVTSVRPGDLKVPASNLTNALAGKVAGVIAFQPSGQPGQDNSNFFIRGVTTFGYKKDPLILIDNVEMTSSDLARLQVDDIESFSILKDASSTALYGARGGNGVILVKTKEGKSGRAKIDVRLERSASESVKNLQLADPITYMKLYNEATLTRNPSAVPLYTPNKIMNTQASMEGAPGSNPFVYPAVNWMDMLFKKRTSTERANLNVSGGGGVARYYIAGSYSNDAGILKTDIRNNNNNNVSFKNYQLRSNVNIDLTKSTELVVRLSGNFNEYRGPMTNDPSFATDLYNIAMHTSPVDFPAFYEPDAANAGVQHILFGNNTDATVLPDGSTLPSSSTDVKNINPYAALLRGNRRFSESRMLAQLELNQKLDFITKGLNFRSIFSTNRYARFESELAYAPYFYNVKSYDKASNQYTLNWINNKPDQAREYLNYYAGASTLNTFLYLQGVLDYAADLNENHNISAALIGTQQQQLNANAKTLFTSLPYRNLGLSGRATYAYKSRYFLEFNFGYNGSERFSENHRYGFFPTMGASWIISDEKFYGHFSNVINRMKLRGSYGLVGNDAISDRRFFYLSDVNLNGGNPAYFGINNGYSHNGVTINNYENRDVTWEISRQINLGLELTFLKNIKLITEVYKNYKSDILQDRANIPTTMGLEAGINANIGKVESQGIEFSLDGKHNFSNDLWISSIANFTFAKNKYTQYEEPDYNEKYRLHTGVAINRNYGYIAERLFVDDTEAQNSPTQIFSSNGIAPRGGDIKYRDLNGDGVVDGKDQTWFGNPTVPEIVYGFGLSSGYKNFDLSVFFQGQARVSFVIDPARTSPFIKSPDSWLPGNTQVIQQYADDHWSEDNQNLYALYPRLGTNGAEIENNRQNSTWWLRDGSFIRMKSLEFGYRFPTKLLNRIKVRNLRVYFSGLNLLTWSPFKMWDPELGGNGFAYPLQKVYNLGINLGI
>NZ_CP049333.1|WP_165305851.1|1526526_1528464_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKTSYSKFLYMAVLIISTVSCKKYLNVTPDNVGTIDYAFRNRNEAENYLFTCYSTLQQMNTPWLDAGFSTSGEIIYPAPNEINDNQGLNPVGFNIMRGTQNAGKPGLNYWDGTEGGQAIFKAIRRCNTMLENIDKPIDLGESEKKRWIAETKFLKAYYHFYLFRMYGPIPIIDVNLPINSSIEDVKVKRAPVDSVVNYMVRLIDEAIPNLPIQIQNPQLELGRITGLIALSVKAQILTTAASPLFNGNPDYIGFSNKDGQPLFNQAKDNTKWDRAAQACSEALNACLANGLRLHTFTPTAAMPANLPKELKDVLTMQTAITEKWELNTELIWGLNPVFGFGLQERFIPRLSAASATNLSSAQGTLSVPIAQQELFYTANGLPIEEDKTWDYRNRYALKTATATDQYHVHNGYETVAAHFKREPRFYAAIAFDGGVWYGNGELNNPTNAFYVQAKGTTSYAGPKDQSHTNITGYWVKKLVNYLTVYGTQMTYENFHFPLMRLSDLYLMYAEVLNEQGKNYSEVLPYIDIVRARANIPAIEDAYTPALSTNPSKYTTQSGLRQIIHQERRIELAFECVPGWDLRRWKELQGVMSKPIQGWNIYNEQSVNYYRPLTLFVPVFSAKNYLWPINSDNFPVNNNLVQNPLW
>NZ_CP049333.1|WP_165305852.1|1528478_1529705_+|DUF4959-domain-containing-protein
MINIKKYTLPLFLLIMVSIISSCKKNNGFNAVISEDTSKPLPVSNVKVDNFTGGANITYNLPNSPNILYVLAKYRVNDNLVRETKSSYYKDTVVVEGFAKEQPYEVTLYTVTRANIMSDPVTVTVNPKIPAYLETRPSLVLSPDFSGVNITGNNPSGKQISIVLLSFNKNTGLMEIEDQFVTKNTKIDHSVFGFNAVERRFAVYVADRWGNLSDTLQTSLTPLFEEAMDKNKFSTLNLSTDTPIDFNWQVQNLWDGRADGSGWHTKFGEPLPYSCSFGIGKTYKLSRFVLFERTGSQYTYKYANPKEFSLWGTNAAIPDNVKLPVRADEGTVIGNWVNLGNFVFPDPPSGNAPANSTAADEDFVKQGVSFRVPFGAPPVKYLRIAVSTVWGREAGAHLMEVTPYGTPE
>NZ_CP049333.1|WP_165305853.1|1529729_1530929_+|hypothetical-protein
MKNNLTTLICCLLALLASCSKQQTDFRDLLGGHEIVYTGLVGQVIEKPGNLRTILTWKKSSDPSIVKYVIFYNQKDSVVVDVTDKKDSVSATITNLEEAVYTFTIYSYDAKGNKSVPKLLNAKIYGPIYQASLLNRPYNGDVPYVAFDNGKVELNFNKPDTVNVTTTVKYTTTANTIKEADLAPTDSILYLNDYKPGTEITYRSFYKPTRNAIDVFSTTSDAVFPQIYFNILCDKSLFRELSLPNDVGTLAESPLRNLWDGSVGPQGYPNIYHSQGNVPLPHTISFDMGKIYNNLSILEETGRNCCHNPDQFEVWGIADISNAATTLPANDAGWKDEAIRKGWTLLLDAVRTDDGSAAKKFELIKNPPPVRYIRIRVKHNANGDTNQSNMSELSFWNGQ
>NZ_CP049333.1|WP_165305854.1|1531007_1533035_+|alpha-galactosidase
MKYFFGILLLLAASMTLSGQTLQIKKNRITFNYNKAKGTYSIGSERQLFINQAVSYLRLANGQKISTDKLTGTRSVTEKPVQDNLGKGIQYTISVKAQQGITLLQHFYFYDTIDGVILEMEVRGKNIASNELVPIWSNASITGLGKSLYQLAVPFDNDTFISYENNVLAMNNKSSSAEVGVVYDKYSGKGLLIGSLDQSVWKSGIAIKGDQGQYTHLAAQAGFTDVNITRDSMAHGAVKGDVIRSPKYLVSYDKDWRIGLENYAKIHRKLSPAYVKSWQGATPVGWNSWGVIQEKLNFQNATGTADYFAKDIPYFRNADGEAFIDLDSFWDNMTPGGMSGDYTQLKQFVLYCDSLGLKPGVYWAPFTDWGHGSGPDRKAEGSQFTFGQLWTKTQKGYHNLDGGRALDPTHPGTLARMDVILGKLVDCGFRMIKVDFLSHAAIESTGFYDKKIQTGMQAYAVGMKHLVDVLQGKMLIYAAISPSLATAQFAHMRRIACDAWKTIDQTQYTLNSVSYGWWQTYLYDFIDADHLVFHDESPEVNKARLLSGVVTGTIILGDDLSKKENWQPKMNQYLQDPEILKIIADGKSFRPAGFVEGKAANTYYYKKIGTALYVAVFNYNTAPAAINIDFKQIGLAPNTTYKAVELFEKAAQEFSAEKSIAFEQAGAKLFKVALF
>NZ_CP049333.1|WP_165305855.1|1533044_1534085_+|GntR-family-transcriptional-regulator
MKKSKEEHFKVLIDRIKRLEALNTLSKHECIVQGVLDAIDANELEVHASLPSVNNLIQYLGYARETFAKAYRDLIAHGVVESKNRKGYFVVSNNTQMKQKVAVLLYAYDTFQDTLVNELRTNLPEEVTVDLFFHHNNMETFEDIFNRIQGRYTVYIVAPIENKDSELLLRSIPASKLLIIDRLVDLGEDYSYVSQEFEEATYAVFQELYPKIKKYKEVIFYFRENTAEPNEIKDAFLRFLKEYKVKGRIEKQYHVGDLKKGKLYFTIHNPELYQMLKEVLQKGWTLGEDLGILSHNDDVIKEIISGGITTFSTSFARIGSQAAKFVLERTLIKEVVPTTLADRNSV

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	NZ_CP049333.1	3186422-3186451	0	1.0
NZ_CP049333_2	2.2|1517338|29|NZ_CP049333|PILER-CR,CRT	1517338-1517366	29	NZ_CP049333.1	5576043-5576071	0	1.0

1. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to position: 3186422-3186451, mismatch: 0, identity: 1.0

aaatatcattcacattatctttattggatt	CRISPR spacer
aaatatcattcacattatctttattggatt	Protospacer
******************************

2. spacer 2.2|1517338|29|NZ_CP049333|PILER-CR,CRT matches to position: 5576043-5576071, mismatch: 0, identity: 1.0

ttaggggctagattattcggtataatttt	CRISPR spacer
ttaggggctagattattcggtataatttt	Protospacer
*****************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP049333_4	4.1|1518028|26|NZ_CP049333|PILER-CR	1518028-1518053	26	NC_017234	Borreliella afzelii PKo plasmid lp28-4, complete sequence	2532-2557	3	0.885
NZ_CP049333_4	4.1|1518028|26|NZ_CP049333|PILER-CR	1518028-1518053	26	NZ_CP009065	Borreliella afzelii K78 plasmid lp28-4, complete sequence	20904-20929	3	0.885
NZ_CP049333_4	4.1|1518028|26|NZ_CP049333|PILER-CR	1518028-1518053	26	LR721753	Aliivibrio wodanis 06/09/160 plasmid 2 complete sequence	31798-31823	4	0.846
NZ_CP049333_4	4.1|1518028|26|NZ_CP049333|PILER-CR	1518028-1518053	26	NZ_CP032091	Pseudoalteromonas donghaensis strain HJ51 plasmid unnamed1, complete sequence	244004-244029	5	0.808
NZ_CP049333_4	4.1|1518028|26|NZ_CP049333|PILER-CR	1518028-1518053	26	NC_012040	Campylobacter lari RM2100 plasmid pCL2100, complete sequence	12838-12863	5	0.808
NZ_CP049333_4	4.1|1518028|26|NZ_CP049333|PILER-CR	1518028-1518053	26	NZ_CP007767	Campylobacter peloridis LMG 23910 plasmid pPEL1, complete sequence	41864-41889	5	0.808
NZ_CP049333_4	4.1|1518028|26|NZ_CP049333|PILER-CR	1518028-1518053	26	MN657067	Psychrobacter sp. strain ANT_P28 plasmid pA28P3, complete sequence	4207-4232	5	0.808
NZ_CP049333_4	4.1|1518028|26|NZ_CP049333|PILER-CR	1518028-1518053	26	NZ_CP044261	Campylobacter armoricus strain CA639 plasmid pCA639-1, complete sequence	43227-43252	5	0.808
NZ_CP049333_4	4.1|1518028|26|NZ_CP049333|PILER-CR	1518028-1518053	26	MK250024	Prevotella phage Lak-B5, complete genome	256503-256528	5	0.808
NZ_CP049333_4	4.1|1518028|26|NZ_CP049333|PILER-CR	1518028-1518053	26	MK250023	Prevotella phage Lak-B4, complete genome	262377-262402	5	0.808
NZ_CP049333_4	4.1|1518028|26|NZ_CP049333|PILER-CR	1518028-1518053	26	MK250027	Prevotella phage Lak-B8, complete genome	261117-261142	5	0.808
NZ_CP049333_4	4.1|1518028|26|NZ_CP049333|PILER-CR	1518028-1518053	26	MK250026	Prevotella phage Lak-B7, complete genome	260175-260200	5	0.808
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	NZ_CP043858	Arcobacter cibarius strain H743 plasmid pACIB, complete sequence	58253-58282	6	0.8
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	MK250029	Prevotella phage Lak-C1, complete genome	521318-521347	6	0.8
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	MK250016	Prevotella phage Lak-A1, complete genome	13866-13895	6	0.8
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	MK250019	Prevotella phage Lak-A2, complete genome	472971-473000	6	0.8
NZ_CP049333_2	2.1|1517273|29|NZ_CP049333|PILER-CR,CRT	1517273-1517301	29	NZ_LR134433	Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 24	6271-6299	6	0.793
NZ_CP049333_4	4.1|1518028|26|NZ_CP049333|PILER-CR	1518028-1518053	26	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	219479-219504	6	0.769
NZ_CP049333_4	4.1|1518028|26|NZ_CP049333|PILER-CR	1518028-1518053	26	NZ_CP029545	Lactobacillus helsingborgensis strain ESL0183 plasmid unnamed	7614-7639	6	0.769
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NZ_CP043858	Arcobacter cibarius strain H743 plasmid pACIB, complete sequence	106827-106856	6	0.8
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NC_011777	Bacillus cereus AH820 plasmid pAH820_272, complete sequence	199283-199312	6	0.8
NZ_CP049333_4	4.5|1518288|29|NZ_CP049333|PILER-CR	1518288-1518316	29	NZ_LR215000	Mycoplasma conjunctivae strain NCTC10147 plasmid 4	14347-14375	6	0.793
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	AP013771	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C37-MedDCM-OCT-S46-C116, *** SEQUENCING IN PROGRESS ***	2380-2409	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	AP013491	Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C37-MedDCM-OCT-S26-C78	3377-3406	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	AP013492	Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C37-MedDCM-OCT-S29-C71	3374-3403	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	AP013493	Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C37-MedDCM-OCT-S32-C82	10876-10905	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	AP013494	Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C37-MedDCM-OCT-S44-C73	30303-30332	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	NZ_LR134422	Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 13	77135-77164	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KX349325	Cyanophage S-RIM12 isolate W1_24_0910, complete genome	118772-118801	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KX349326	Cyanophage S-RIM12 isolate WH_05_0310, complete genome	118936-118965	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KX349327	Cyanophage S-RIM12 isolate WH_07_0310, complete genome	118025-118054	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KX349322	Cyanophage S-RIM12 isolate Sn_31_0910, complete genome	118780-118809	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KX349320	Cyanophage S-RIM12 isolate RW_29_1109, complete genome	119330-119359	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KX349310	Cyanophage S-RIM12 isolate RW_01_0310, complete genome	119305-119334	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KX349321	Cyanophage S-RIM12 isolate Sn_07_0910, complete genome	118988-119017	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KX349324	Cyanophage S-RIM12 isolate W1_12_0610, complete genome	118384-118413	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KX349314	Cyanophage S-RIM12 isolate RW_07_1112, complete genome	119331-119360	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KX349308	Cyanophage S-RIM12 isolate Np_15_0310, complete genome	118936-118965	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KX349316	Cyanophage S-RIM12 isolate RW_22_0110, complete genome	119333-119362	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KX349312	Cyanophage S-RIM12 isolate RW_04_0709, complete genome	119015-119044	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KX349315	Cyanophage S-RIM12 isolate RW_14_0101, complete genome	119025-119054	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KX349317	Cyanophage S-RIM12 isolate RW_25_0210, complete genome	119173-119202	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KX349311	Cyanophage S-RIM12 isolate RW_04_0310, complete genome	118933-118962	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KX349323	Cyanophage S-RIM12 isolate W1_08_0910, complete genome	117884-117913	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KX349313	Cyanophage S-RIM12 isolate RW_06_0310, complete genome	117882-117911	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	NC_015285	Prochlorococcus phage Syn33, complete genome	119325-119354	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KX349309	Cyanophage S-RIM12 isolate Np_22_1112, complete genome	119168-119197	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KX349319	Cyanophage S-RIM12 isolate RW_28_1109, complete genome	118044-118073	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KX349307	Cyanophage S-RIM12 isolate Np_14_0310, complete genome	118050-118079	7	0.767
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KX349318	Cyanophage S-RIM12 isolate RW_27_0310, complete genome	119076-119105	7	0.767
NZ_CP049333_4	4.1|1518028|26|NZ_CP049333|PILER-CR	1518028-1518053	26	NZ_CP022446	Bacillus cereus C1L plasmid pC1L1, complete sequence	100716-100741	7	0.731
NZ_CP049333_4	4.1|1518028|26|NZ_CP049333|PILER-CR	1518028-1518053	26	NZ_CP007513	Bacillus bombysepticus plasmid pBb, complete genome	399284-399309	7	0.731
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NZ_CP047086	Bacillus paranthracis strain BC307 plasmid pCE1, complete sequence	39195-39224	7	0.767
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NC_005707	Bacillus cereus ATCC 10987 plasmid pBc10987, complete sequence	191611-191640	7	0.767
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NZ_CP040343	Bacillus cereus strain DLOU-Weihai plasmid unnamed1, complete sequence	48516-48545	7	0.767
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NZ_CP033789	Bacillus sp. FDAARGOS_527 plasmid unnamed2, complete sequence	53555-53584	7	0.767
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NZ_KY940428	UNVERIFIED: Bacillus sp. (in: Bacteria) strain PUMK-07 plasmid pMK-07, complete sequence	145015-145044	7	0.767
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NZ_CP041978	Bacillus pacificus strain NCCP 15909 plasmid unnamed1, complete sequence	61633-61662	7	0.767
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NC_011655	Bacillus cereus AH187 plasmid pAH187_270, complete sequence	124347-124376	7	0.767
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NZ_CP045534	Bacillaceae bacterium C02 plasmid unnamed1, complete sequence	102600-102629	7	0.767
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NC_010924	Bacillus cereus strain AH187 plasmid pCER270, complete sequence	180756-180785	7	0.767
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	CP045776	Bacillus paranthracis strain CFSAN068816 plasmid p1CFSAN068816, complete sequence	171732-171761	7	0.767
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	CP041980	Bacillus paranthracis strain NCCP 15910 plasmid unnamed, complete sequence	46026-46055	7	0.767
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NC_016792	Bacillus cereus NC7401 plasmid pNCcld, complete sequence	179625-179654	7	0.767
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NZ_KT897276	Clostridium botulinum strain INGR16-02E1 plasmid pINGR16-02E1, complete sequence	118978-119007	7	0.767
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NZ_KT897280	Clostridium botulinum strain FI1111E1 plasmid pFI1111E1, complete sequence	128704-128733	7	0.767
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NZ_KT897277	Clostridium botulinum strain ST0210E1 plasmid pST0210E1, complete sequence	118978-119007	7	0.767
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NZ_KT897278	Clostridium botulinum strain FWSKR40E1 plasmid pFWSKR40E1, complete sequence	126129-126158	7	0.767
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NZ_KT897279	Clostridium botulinum strain SWKR38E2 plasmid pSWKR38E2, complete sequence	127265-127294	7	0.767
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	KF114877	Leptospira phage LnoZ_CZ214, complete genome	43121-43150	7	0.767
NZ_CP049333_4	4.6|1518022|32|NZ_CP049333|CRISPRCasFinder	1518022-1518053	32	NZ_CP007767	Campylobacter peloridis LMG 23910 plasmid pPEL1, complete sequence	41858-41889	7	0.781
NZ_CP049333_4	4.6|1518022|32|NZ_CP049333|CRISPRCasFinder	1518022-1518053	32	NZ_CP044261	Campylobacter armoricus strain CA639 plasmid pCA639-1, complete sequence	43221-43252	7	0.781
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	NZ_CP053689	Arthrobacter citreus strain NEB 577 plasmid unnamed1, complete sequence	207692-207721	8	0.733
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	NZ_CP011627	Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-14, complete sequence	196-225	8	0.733
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	MK504445	Lactobacillus phage ATCCB, complete genome	34337-34366	8	0.733
NZ_CP049333_4	4.3|1518156|30|NZ_CP049333|PILER-CR	1518156-1518185	30	AP013702	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C113A-MedDCM-OCT-S33-C15, *** SEQUENCING IN PROGRESS ***	5255-5284	8	0.733
NZ_CP049333_4	4.3|1518156|30|NZ_CP049333|PILER-CR	1518156-1518185	30	AP013438	Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-C113A-MedDCM-OCT-S35-C17	39056-39085	8	0.733
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NZ_CP040341	Bacillus cereus strain DLOU-Tangshan plasmid unnamed1, complete sequence	74519-74548	8	0.733
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NZ_CP018028	Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence	291457-291486	8	0.733
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NZ_CP018025	Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence	291598-291627	8	0.733
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NZ_CP042928	Bacillus cereus strain G1-1 plasmid unnamed, complete sequence	228732-228761	8	0.733
NZ_CP049333_4	4.6|1518022|32|NZ_CP049333|CRISPRCasFinder	1518022-1518053	32	NZ_CP009065	Borreliella afzelii K78 plasmid lp28-4, complete sequence	20898-20929	8	0.75
NZ_CP049333_4	4.6|1518022|32|NZ_CP049333|CRISPRCasFinder	1518022-1518053	32	NC_017234	Borreliella afzelii PKo plasmid lp28-4, complete sequence	2532-2563	8	0.75
NZ_CP049333_4	4.6|1518022|32|NZ_CP049333|CRISPRCasFinder	1518022-1518053	32	LR721753	Aliivibrio wodanis 06/09/160 plasmid 2 complete sequence	31798-31829	8	0.75
NZ_CP049333_4	4.6|1518022|32|NZ_CP049333|CRISPRCasFinder	1518022-1518053	32	NC_012040	Campylobacter lari RM2100 plasmid pCL2100, complete sequence	12838-12869	8	0.75
NZ_CP049333_4	4.6|1518022|32|NZ_CP049333|CRISPRCasFinder	1518022-1518053	32	MN657067	Psychrobacter sp. strain ANT_P28 plasmid pA28P3, complete sequence	4201-4232	8	0.75
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KY653120	Staphylococcus phage IME1348_01, complete genome	33554-33583	9	0.7
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	JN192400	Staphylococcus phage vB_SepiS-phiIPLA5, complete genome	17900-17929	9	0.7
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	KU598975	Staphylococcus phage CNPx, complete genome	17954-17983	9	0.7
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	JN192401	Staphylococcus phage vB_SepiS-phiIPLA7, complete genome	17498-17527	9	0.7
NZ_CP049333_1	1.11|1516907|30|NZ_CP049333|CRT	1516907-1516936	30	DQ831957	Staphylococcus phage CNPH82, complete genome	17954-17983	9	0.7
NZ_CP049333_4	4.3|1518156|30|NZ_CP049333|PILER-CR	1518156-1518185	30	NC_013793	Bacillus pseudofirmus OF4 plasmid pBpOF4-02, complete sequence	54388-54417	9	0.7
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	MT774389	CrAssphage cr116_1, complete genome	61834-61863	9	0.7
NZ_CP049333_4	4.3|1518156|30|NZ_CP049333|PILER-CR	1518156-1518185	30	NZ_LR214999	Mycoplasma conjunctivae strain NCTC10147 plasmid 3	59476-59505	10	0.667
NZ_CP049333_4	4.3|1518156|30|NZ_CP049333|PILER-CR	1518156-1518185	30	LR214965	Mycoplasma fermentans strain NCTC10117 genome assembly, plasmid: 11	49068-49097	10	0.667
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	KX160215	Lactococcus phage 98104, complete genome	12348-12377	10	0.667
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	KX160205	Lactococcus phage 49801, complete genome	13124-13153	10	0.667
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	AF208055	Bacteriophage phi31.1 Orf238 (orf238), Orf92 (orf92), Orf78 (orf78), Orf57 (orf57), Orf245 (orf245), Orf364 (orf364), Orf269 (orf269), Orf73 (orf73), Orf139a (orf139a), Orf79 (orf79), Orf85 (orf85), Orf68 (orf68), Orf63 (orf63), Orf75 (orf75), Orf139b (orf139b), Orf118 (orf118), Orf64 (orf64), Orf120 (orf120), Orf230 (orf230), Orf80 (orf80), Orf66 (orf66), Orf61a (orf61a), and Orf61b (orf61b) genes, complete cds	7652-7681	10	0.667
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	AF212846	Lactococcus lactis bacteriophage ul36.1 ORF111a (ORF111a), ORF78b (ORF78b), ORF61b (ORF61b), ORF245 (ORF245), ORF364 (ORF364), ORF235 (ORF235), ORF73 (ORF73), ORF109 (ORF109), ORF79b (ORF79b), ORF174 (ORF174), ORF68c (ORF68c), ORF184 (ORF184), putative dUTPase (ORF139b), ORF118a (ORF118a), and ORF65 (ORF65) genes, complete cds; and ORF120a gene, complete sequence	7572-7601	10	0.667
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	KX160212	Lactococcus phage 98101, complete genome	12124-12153	10	0.667
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	AF212845	Lactococcus lactis bacteriophage ul36 ORF111a (ORF111a), ORF78a (ORF78a), ORF61a (ORF61a), ORF131 (ORF131), ORF252 (ORF252), putative single stranded binding protein (ORF141), putative replisome organizer (ORF255), ORF241 (ORF241), ORF129 (ORF129), ORF129 (ORF79a), ORF68a (ORF68a), ORF56 (ORF56), ORF68b (ORF68b), ORF237 (ORF237), putative dUTPase (ORF139a), ORF118a (ORF118a), ORF65 (ORF65), and ORF120a (ORF120a) genes, complete cds	7826-7855	10	0.667
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	MN534316	Lactococcus phage proPhi2, complete genome	12954-12983	10	0.667
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	DQ394806	Lactococcus phage ul36.k1, complete genome	13690-13719	10	0.667
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	KX160214	Lactococcus phage 98103, complete genome	12989-13018	10	0.667
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	MN534317	Lactococcus phage proPhi4, complete genome	12954-12983	10	0.667
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	KX160213	Lactococcus phage 98102, complete genome	12054-12083	10	0.667
NZ_CP049333_4	4.4|1518222|30|NZ_CP049333|PILER-CR	1518222-1518251	30	NC_004066	Lactococcus phage ul36, complete genome	13357-13386	10	0.667

1. spacer 4.1|1518028|26|NZ_CP049333|PILER-CR matches to NC_017234 (Borreliella afzelii PKo plasmid lp28-4, complete sequence) position: , mismatch: 3, identity: 0.885

ggttaataataaatttaattgctcta	CRISPR spacer
agtaaataataaatttaattactcta	Protospacer
.** ****************.*****

2. spacer 4.1|1518028|26|NZ_CP049333|PILER-CR matches to NZ_CP009065 (Borreliella afzelii K78 plasmid lp28-4, complete sequence) position: , mismatch: 3, identity: 0.885

ggttaataataaatttaattgctcta	CRISPR spacer
agtaaataataaatttaattactcta	Protospacer
.** ****************.*****

3. spacer 4.1|1518028|26|NZ_CP049333|PILER-CR matches to LR721753 (Aliivibrio wodanis 06/09/160 plasmid 2 complete sequence) position: , mismatch: 4, identity: 0.846

ggttaataataaatttaattgctcta	CRISPR spacer
acttaataataaatttaatcgttcta	Protospacer
. *****************.*.****

4. spacer 4.1|1518028|26|NZ_CP049333|PILER-CR matches to NZ_CP032091 (Pseudoalteromonas donghaensis strain HJ51 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.808

ggttaataataaatttaattgctcta	CRISPR spacer
ttttaataataaagttaattgctcag	Protospacer
  *********** ********** .

5. spacer 4.1|1518028|26|NZ_CP049333|PILER-CR matches to NC_012040 (Campylobacter lari RM2100 plasmid pCL2100, complete sequence) position: , mismatch: 5, identity: 0.808

ggttaataataaatttaattgctcta	CRISPR spacer
atctaatgctaaatttaattgctcta	Protospacer
. .****. *****************

6. spacer 4.1|1518028|26|NZ_CP049333|PILER-CR matches to NZ_CP007767 (Campylobacter peloridis LMG 23910 plasmid pPEL1, complete sequence) position: , mismatch: 5, identity: 0.808

ggttaataataaatttaattgctcta	CRISPR spacer
atctaatgctaaatttaattgctcta	Protospacer
. .****. *****************

7. spacer 4.1|1518028|26|NZ_CP049333|PILER-CR matches to MN657067 (Psychrobacter sp. strain ANT_P28 plasmid pA28P3, complete sequence) position: , mismatch: 5, identity: 0.808

ggttaataataaatttaattgctcta	CRISPR spacer
ttctaatattaaatttacttgctcta	Protospacer
  .***** ******** ********

8. spacer 4.1|1518028|26|NZ_CP049333|PILER-CR matches to NZ_CP044261 (Campylobacter armoricus strain CA639 plasmid pCA639-1, complete sequence) position: , mismatch: 5, identity: 0.808

ggttaataataaatttaattgctcta	CRISPR spacer
atctaatgctaaatttaattgctcta	Protospacer
. .****. *****************

9. spacer 4.1|1518028|26|NZ_CP049333|PILER-CR matches to MK250024 (Prevotella phage Lak-B5, complete genome) position: , mismatch: 5, identity: 0.808

ggttaataataaatttaattgctcta	CRISPR spacer
ttttaataataaatttaaatgctaaa	Protospacer
  **************** ****  *

10. spacer 4.1|1518028|26|NZ_CP049333|PILER-CR matches to MK250023 (Prevotella phage Lak-B4, complete genome) position: , mismatch: 5, identity: 0.808

ggttaataataaatttaattgctcta	CRISPR spacer
ttttaataataaatttaaatgctaaa	Protospacer
  **************** ****  *

11. spacer 4.1|1518028|26|NZ_CP049333|PILER-CR matches to MK250027 (Prevotella phage Lak-B8, complete genome) position: , mismatch: 5, identity: 0.808

ggttaataataaatttaattgctcta	CRISPR spacer
ttttaataataaatttaaatgctaaa	Protospacer
  **************** ****  *

12. spacer 4.1|1518028|26|NZ_CP049333|PILER-CR matches to MK250026 (Prevotella phage Lak-B7, complete genome) position: , mismatch: 5, identity: 0.808

ggttaataataaatttaattgctcta	CRISPR spacer
ttttaataataaatttaaatgctaaa	Protospacer
  **************** ****  *

13. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to NZ_CP043858 (Arcobacter cibarius strain H743 plasmid pACIB, complete sequence) position: , mismatch: 6, identity: 0.8

aaatatcattcacattatctttattggatt	CRISPR spacer
aaatatcattcacattattttcatttatat	Protospacer
******************.**.*** .  *

14. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to MK250029 (Prevotella phage Lak-C1, complete genome) position: , mismatch: 6, identity: 0.8

aaatatcattcacattatctttattggatt	CRISPR spacer
caatatcatttatattatctttattaaata	Protospacer
 *********.*.************..** 

15. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to MK250016 (Prevotella phage Lak-A1, complete genome) position: , mismatch: 6, identity: 0.8

aaatatcattcacattatctttattggatt	CRISPR spacer
caatatcatttatattatctttattaaata	Protospacer
 *********.*.************..** 

16. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to MK250019 (Prevotella phage Lak-A2, complete genome) position: , mismatch: 6, identity: 0.8

aaatatcattcacattatctttattggatt	CRISPR spacer
caatatcatttatattatctttattaaata	Protospacer
 *********.*.************..** 

17. spacer 2.1|1517273|29|NZ_CP049333|PILER-CR,CRT matches to NZ_LR134433 (Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 24) position: , mismatch: 6, identity: 0.793

ttaacgctaacctttatcatttaattggt	CRISPR spacer
tggaatctaacatttatcatttaattgga	Protospacer
* .*  ***** **************** 

18. spacer 4.1|1518028|26|NZ_CP049333|PILER-CR matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 6, identity: 0.769

ggttaataataaatttaattgctcta	CRISPR spacer
atattttaataaatttaattgctctt	Protospacer
.  *  ******************* 

19. spacer 4.1|1518028|26|NZ_CP049333|PILER-CR matches to NZ_CP029545 (Lactobacillus helsingborgensis strain ESL0183 plasmid unnamed) position: , mismatch: 6, identity: 0.769

ggttaataataaatttaattgctcta	CRISPR spacer
ttgtaataataattttaattgctcat	Protospacer
   ********* ***********  

20. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NZ_CP043858 (Arcobacter cibarius strain H743 plasmid pACIB, complete sequence) position: , mismatch: 6, identity: 0.8

attataaattctatcaaatctttttgagaa	CRISPR spacer
ttaataaattctatcatatcttgttgatat	Protospacer
 * ************* ***** **** * 

21. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NC_011777 (Bacillus cereus AH820 plasmid pAH820_272, complete sequence) position: , mismatch: 6, identity: 0.8

attataaattctatcaaatctttttgagaa	CRISPR spacer
gtcacaaattctttcaaatctttttgaata	Protospacer
.*.*.******* **************. *

22. spacer 4.5|1518288|29|NZ_CP049333|PILER-CR matches to NZ_LR215000 (Mycoplasma conjunctivae strain NCTC10147 plasmid 4) position: , mismatch: 6, identity: 0.793

gagtttagaaatcttaagataaactgtcc	CRISPR spacer
tattttataaatcttaagataaaatgctc	Protospacer
 * **** *************** **..*

23. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to AP013771 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C37-MedDCM-OCT-S46-C116, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
aaacatcattaacattatctttatcaggag	Protospacer
***.****** *************..*.  

24. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to AP013491 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C37-MedDCM-OCT-S26-C78) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
aaacatcattaacattatctttatcaggag	Protospacer
***.****** *************..*.  

25. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to AP013492 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C37-MedDCM-OCT-S29-C71) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
aaacatcattaacattatctttatcaggag	Protospacer
***.****** *************..*.  

26. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to AP013493 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C37-MedDCM-OCT-S32-C82) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
aaacatcattaacattatctttatcaggag	Protospacer
***.****** *************..*.  

27. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to AP013494 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G19, isolate: uvMED-CGR-C37-MedDCM-OCT-S44-C73) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
aaacatcattaacattatctttatcaggag	Protospacer
***.****** *************..*.  

28. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to NZ_LR134422 (Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 13) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
gtatatcattccaattatctttattttttt	Protospacer
. *********  ************   **

29. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KX349325 (Cyanophage S-RIM12 isolate W1_24_0910, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

30. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KX349326 (Cyanophage S-RIM12 isolate WH_05_0310, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

31. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KX349327 (Cyanophage S-RIM12 isolate WH_07_0310, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

32. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KX349322 (Cyanophage S-RIM12 isolate Sn_31_0910, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

33. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KX349320 (Cyanophage S-RIM12 isolate RW_29_1109, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

34. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KX349310 (Cyanophage S-RIM12 isolate RW_01_0310, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

35. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KX349321 (Cyanophage S-RIM12 isolate Sn_07_0910, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

36. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KX349324 (Cyanophage S-RIM12 isolate W1_12_0610, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

37. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KX349314 (Cyanophage S-RIM12 isolate RW_07_1112, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

38. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KX349308 (Cyanophage S-RIM12 isolate Np_15_0310, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

39. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KX349316 (Cyanophage S-RIM12 isolate RW_22_0110, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

40. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KX349312 (Cyanophage S-RIM12 isolate RW_04_0709, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

41. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KX349315 (Cyanophage S-RIM12 isolate RW_14_0101, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

42. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KX349317 (Cyanophage S-RIM12 isolate RW_25_0210, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

43. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KX349311 (Cyanophage S-RIM12 isolate RW_04_0310, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

44. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KX349323 (Cyanophage S-RIM12 isolate W1_08_0910, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

45. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KX349313 (Cyanophage S-RIM12 isolate RW_06_0310, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

46. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to NC_015285 (Prochlorococcus phage Syn33, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

47. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KX349309 (Cyanophage S-RIM12 isolate Np_22_1112, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

48. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KX349319 (Cyanophage S-RIM12 isolate RW_28_1109, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

49. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KX349307 (Cyanophage S-RIM12 isolate Np_14_0310, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

50. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KX349318 (Cyanophage S-RIM12 isolate RW_27_0310, complete genome) position: , mismatch: 7, identity: 0.767

aaatatcattcacattatctttattggatt	CRISPR spacer
ccaagtaatacacattacctttattggatt	Protospacer
  * .* ** *******.************

51. spacer 4.1|1518028|26|NZ_CP049333|PILER-CR matches to NZ_CP022446 (Bacillus cereus C1L plasmid pC1L1, complete sequence) position: , mismatch: 7, identity: 0.731

ggttaataataaatttaattgctcta	CRISPR spacer
atttaataataaatttaattgggaag	Protospacer
. *******************    .

52. spacer 4.1|1518028|26|NZ_CP049333|PILER-CR matches to NZ_CP007513 (Bacillus bombysepticus plasmid pBb, complete genome) position: , mismatch: 7, identity: 0.731

ggttaataataaatttaattgctcta	CRISPR spacer
atttaataataaatttaattgggaag	Protospacer
. *******************    .

53. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NZ_CP047086 (Bacillus paranthracis strain BC307 plasmid pCE1, complete sequence) position: , mismatch: 7, identity: 0.767

attataaattctatcaaatctttttgagaa	CRISPR spacer
gccacaaattctttcaaatctttttgaata	Protospacer
...*.******* **************. *

54. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NC_005707 (Bacillus cereus ATCC 10987 plasmid pBc10987, complete sequence) position: , mismatch: 7, identity: 0.767

attataaattctatcaaatctttttgagaa	CRISPR spacer
gccacaaattctttcaaatctttttgaata	Protospacer
...*.******* **************. *

55. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NZ_CP040343 (Bacillus cereus strain DLOU-Weihai plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

attataaattctatcaaatctttttgagaa	CRISPR spacer
gccacaaattctttcaaatctttttgaata	Protospacer
...*.******* **************. *

56. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NZ_CP033789 (Bacillus sp. FDAARGOS_527 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

attataaattctatcaaatctttttgagaa	CRISPR spacer
gccacaaattctttcaaatctttttgaata	Protospacer
...*.******* **************. *

57. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NZ_KY940428 (UNVERIFIED: Bacillus sp. (in: Bacteria) strain PUMK-07 plasmid pMK-07, complete sequence) position: , mismatch: 7, identity: 0.767

attataaattctatcaaatctttttgagaa	CRISPR spacer
gccacaaattctttcaaatctttttgaata	Protospacer
...*.******* **************. *

58. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NZ_CP041978 (Bacillus pacificus strain NCCP 15909 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

attataaattctatcaaatctttttgagaa	CRISPR spacer
gccacaaattctttcaaatctttttgaata	Protospacer
...*.******* **************. *

59. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NC_011655 (Bacillus cereus AH187 plasmid pAH187_270, complete sequence) position: , mismatch: 7, identity: 0.767

attataaattctatcaaatctttttgagaa	CRISPR spacer
gccacaaattctttcaaatctttttgaata	Protospacer
...*.******* **************. *

60. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NZ_CP045534 (Bacillaceae bacterium C02 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

attataaattctatcaaatctttttgagaa	CRISPR spacer
gccacaaattctttcaaatctttttgaata	Protospacer
...*.******* **************. *

61. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NC_010924 (Bacillus cereus strain AH187 plasmid pCER270, complete sequence) position: , mismatch: 7, identity: 0.767

attataaattctatcaaatctttttgagaa	CRISPR spacer
gccacaaattctttcaaatctttttgaata	Protospacer
...*.******* **************. *

62. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to CP045776 (Bacillus paranthracis strain CFSAN068816 plasmid p1CFSAN068816, complete sequence) position: , mismatch: 7, identity: 0.767

attataaattctatcaaatctttttgagaa	CRISPR spacer
gccacaaattctttcaaatctttttgaata	Protospacer
...*.******* **************. *

63. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to CP041980 (Bacillus paranthracis strain NCCP 15910 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

attataaattctatcaaatctttttgagaa	CRISPR spacer
gccacaaattctttcaaatctttttgaata	Protospacer
...*.******* **************. *

64. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NC_016792 (Bacillus cereus NC7401 plasmid pNCcld, complete sequence) position: , mismatch: 7, identity: 0.767

attataaattctatcaaatctttttgagaa	CRISPR spacer
gccacaaattctttcaaatctttttgaata	Protospacer
...*.******* **************. *

65. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NZ_KT897276 (Clostridium botulinum strain INGR16-02E1 plasmid pINGR16-02E1, complete sequence) position: , mismatch: 7, identity: 0.767

attataaattctatcaaatc-----tttttgagaa	CRISPR spacer
attataaatttcatcaaatctttgattttt-----	Protospacer
**********..********     *****     

66. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NZ_KT897280 (Clostridium botulinum strain FI1111E1 plasmid pFI1111E1, complete sequence) position: , mismatch: 7, identity: 0.767

attataaattctatcaaatctttttgagaa----	CRISPR spacer
attataaatttcatcaaatcttt----gattttc	Protospacer
**********..***********    **     

67. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NZ_KT897277 (Clostridium botulinum strain ST0210E1 plasmid pST0210E1, complete sequence) position: , mismatch: 7, identity: 0.767

attataaattctatcaaatc-----tttttgagaa	CRISPR spacer
attataaatttcatcaaatctttgattttt-----	Protospacer
**********..********     *****     

68. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NZ_KT897278 (Clostridium botulinum strain FWSKR40E1 plasmid pFWSKR40E1, complete sequence) position: , mismatch: 7, identity: 0.767

attataaattctatcaaatctttttgagaa----	CRISPR spacer
attataaatttcatcaaatcttt----gattttc	Protospacer
**********..***********    **     

69. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NZ_KT897279 (Clostridium botulinum strain SWKR38E2 plasmid pSWKR38E2, complete sequence) position: , mismatch: 7, identity: 0.767

attataaattctatcaaatctttttgagaa----	CRISPR spacer
attataaatttcatcaaatcttt----gattttc	Protospacer
**********..***********    **     

70. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to KF114877 (Leptospira phage LnoZ_CZ214, complete genome) position: , mismatch: 7, identity: 0.767

attataaattctatcaaatctttttgagaa	CRISPR spacer
ttttctaattctataaaatctttttcagat	Protospacer
 ** . ******** ********** *** 

71. spacer 4.6|1518022|32|NZ_CP049333|CRISPRCasFinder matches to NZ_CP007767 (Campylobacter peloridis LMG 23910 plasmid pPEL1, complete sequence) position: , mismatch: 7, identity: 0.781

tacagcggttaataataaatttaattgctcta	CRISPR spacer
taaatcatctaatgctaaatttaattgctcta	Protospacer
** * *. .****. *****************

72. spacer 4.6|1518022|32|NZ_CP049333|CRISPRCasFinder matches to NZ_CP044261 (Campylobacter armoricus strain CA639 plasmid pCA639-1, complete sequence) position: , mismatch: 7, identity: 0.781

tacagcggttaataataaatttaattgctcta	CRISPR spacer
taaatcatctaatgctaaatttaattgctcta	Protospacer
** * *. .****. *****************

73. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to NZ_CP053689 (Arthrobacter citreus strain NEB 577 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aaatatcattcacattatctttattggatt	CRISPR spacer
ttatatcaatgacattatctttattcacat	Protospacer
  ****** * ************** .  *

74. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to NZ_CP011627 (Klebsiella oxytoca strain CAV1374 plasmid pCAV1374-14, complete sequence) position: , mismatch: 8, identity: 0.733

aaatatcattcacattatctttattggatt	CRISPR spacer
gaatatcattcaccttacctttatacaagg	Protospacer
.************ ***.******  .*  

75. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to MK504445 (Lactobacillus phage ATCCB, complete genome) position: , mismatch: 8, identity: 0.733

aaatatcattcacattatctttattggatt	CRISPR spacer
aaatatcattcatattatcttctttaatca	Protospacer
************.********. **.. . 

76. spacer 4.3|1518156|30|NZ_CP049333|PILER-CR matches to AP013702 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C113A-MedDCM-OCT-S33-C15, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 8, identity: 0.733

tccaagcttttgaaaccaaatattttcttt	CRISPR spacer
atttaaattttgaatccatatattttcttt	Protospacer
 .. *. ******* *** ***********

77. spacer 4.3|1518156|30|NZ_CP049333|PILER-CR matches to AP013438 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-C113A-MedDCM-OCT-S35-C17) position: , mismatch: 8, identity: 0.733

tccaagcttttgaaaccaaatattttcttt	CRISPR spacer
atttaaattttgaatccatatattttcttt	Protospacer
 .. *. ******* *** ***********

78. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NZ_CP040341 (Bacillus cereus strain DLOU-Tangshan plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

attataaattctatcaaatctttttgagaa	CRISPR spacer
gccacgaattctttcaaatctttttgaata	Protospacer
...*..****** **************. *

79. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NZ_CP018028 (Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence) position: , mismatch: 8, identity: 0.733

attataaattctatcaaatctttttgagaa	CRISPR spacer
attataaattctatctattctttatttcgt	Protospacer
*************** * ***** *   . 

80. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NZ_CP018025 (Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence) position: , mismatch: 8, identity: 0.733

attataaattctatcaaatctttttgagaa	CRISPR spacer
attataaattctatctattctttatttcgt	Protospacer
*************** * ***** *   . 

81. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NZ_CP042928 (Bacillus cereus strain G1-1 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

attataaattctatcaaatctttttgagaa	CRISPR spacer
gccacgaattctttcaaatctttttgaata	Protospacer
...*..****** **************. *

82. spacer 4.6|1518022|32|NZ_CP049333|CRISPRCasFinder matches to NZ_CP009065 (Borreliella afzelii K78 plasmid lp28-4, complete sequence) position: , mismatch: 8, identity: 0.75

tacagcggttaataataaatttaattgctcta	CRISPR spacer
gtctttagtaaataataaatttaattactcta	Protospacer
  *  ..** ****************.*****

83. spacer 4.6|1518022|32|NZ_CP049333|CRISPRCasFinder matches to NC_017234 (Borreliella afzelii PKo plasmid lp28-4, complete sequence) position: , mismatch: 8, identity: 0.75

tacagcggttaataataaatttaattgctcta	CRISPR spacer
gtctttagtaaataataaatttaattactcta	Protospacer
  *  ..** ****************.*****

84. spacer 4.6|1518022|32|NZ_CP049333|CRISPRCasFinder matches to LR721753 (Aliivibrio wodanis 06/09/160 plasmid 2 complete sequence) position: , mismatch: 8, identity: 0.75

tacagcggttaataataaatttaattgctcta	CRISPR spacer
tccctaacttaataataaatttaatcgttcta	Protospacer
* *   . *****************.*.****

85. spacer 4.6|1518022|32|NZ_CP049333|CRISPRCasFinder matches to NC_012040 (Campylobacter lari RM2100 plasmid pCL2100, complete sequence) position: , mismatch: 8, identity: 0.75

tacagcggttaataataaatttaattgctcta	CRISPR spacer
taaattatctaatgctaaatttaattgctcta	Protospacer
** * .. .****. *****************

86. spacer 4.6|1518022|32|NZ_CP049333|CRISPRCasFinder matches to MN657067 (Psychrobacter sp. strain ANT_P28 plasmid pA28P3, complete sequence) position: , mismatch: 8, identity: 0.75

tacagcggt--taataataaatttaattgctcta	CRISPR spacer
--caataattctaatattaaatttacttgctcta	Protospacer
  **....*  ***** ******** ********

87. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KY653120 (Staphylococcus phage IME1348_01, complete genome) position: , mismatch: 9, identity: 0.7

aaatatcattcacattatctttattggatt	CRISPR spacer
ctttaccattcacattatctttatatccta	Protospacer
   **.******************    * 

88. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to JN192400 (Staphylococcus phage vB_SepiS-phiIPLA5, complete genome) position: , mismatch: 9, identity: 0.7

aaatatcattcacattatctttattggatt	CRISPR spacer
ctttaccattcacattatctttatatccta	Protospacer
   **.******************    * 

89. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to KU598975 (Staphylococcus phage CNPx, complete genome) position: , mismatch: 9, identity: 0.7

aaatatcattcacattatctttattggatt	CRISPR spacer
ctttaccattcacattatctttatatccta	Protospacer
   **.******************    * 

90. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to JN192401 (Staphylococcus phage vB_SepiS-phiIPLA7, complete genome) position: , mismatch: 9, identity: 0.7

aaatatcattcacattatctttattggatt	CRISPR spacer
ctttaccattcacattatctttatatccta	Protospacer
   **.******************    * 

91. spacer 1.11|1516907|30|NZ_CP049333|CRT matches to DQ831957 (Staphylococcus phage CNPH82, complete genome) position: , mismatch: 9, identity: 0.7

aaatatcattcacattatctttattggatt	CRISPR spacer
ctttaccattcacattatctttatatccta	Protospacer
   **.******************    * 

92. spacer 4.3|1518156|30|NZ_CP049333|PILER-CR matches to NC_013793 (Bacillus pseudofirmus OF4 plasmid pBpOF4-02, complete sequence) position: , mismatch: 9, identity: 0.7

tccaagcttttgaaaccaaatattttcttt	CRISPR spacer
cagatttctttgaaactaaatattttcttc	Protospacer
.  *  ..********.************.

93. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to MT774389 (CrAssphage cr116_1, complete genome) position: , mismatch: 9, identity: 0.7

attataaattctatcaaatctttttgagaa	CRISPR spacer
gttataaattctttcaaatattttattatt	Protospacer
.*********** ****** ****   .  

94. spacer 4.3|1518156|30|NZ_CP049333|PILER-CR matches to NZ_LR214999 (Mycoplasma conjunctivae strain NCTC10147 plasmid 3) position: , mismatch: 10, identity: 0.667

tccaagcttttgaaaccaaatattttcttt	CRISPR spacer
gtttgtactttgaaaccaaatattttttta	Protospacer
 .. .  .******************.** 

95. spacer 4.3|1518156|30|NZ_CP049333|PILER-CR matches to LR214965 (Mycoplasma fermentans strain NCTC10117 genome assembly, plasmid: 11) position: , mismatch: 10, identity: 0.667

tccaagcttttgaaaccaaatattttcttt	CRISPR spacer
gtttgtactttgaaaccaaatattttttta	Protospacer
 .. .  .******************.** 

96. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to KX160215 (Lactococcus phage 98104, complete genome) position: , mismatch: 10, identity: 0.667

attataaattctatcaaatctttttgagaa	CRISPR spacer
tggataaattctataaaatcttttacctgt	Protospacer
   *********** *********    . 

97. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to KX160205 (Lactococcus phage 49801, complete genome) position: , mismatch: 10, identity: 0.667

attataaattctatcaaatctttttgagaa	CRISPR spacer
tggataaattctataaaatcttttacctgt	Protospacer
   *********** *********    . 

98. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to AF208055 (Bacteriophage phi31.1 Orf238 (orf238), Orf92 (orf92), Orf78 (orf78), Orf57 (orf57), Orf245 (orf245), Orf364 (orf364), Orf269 (orf269), Orf73 (orf73), Orf139a (orf139a), Orf79 (orf79), Orf85 (orf85), Orf68 (orf68), Orf63 (orf63), Orf75 (orf75), Orf139b (orf139b), Orf118 (orf118), Orf64 (orf64), Orf120 (orf120), Orf230 (orf230), Orf80 (orf80), Orf66 (orf66), Orf61a (orf61a), and Orf61b (orf61b) genes, complete cds) position: , mismatch: 10, identity: 0.667

attataaattctatcaaatctttttgagaa	CRISPR spacer
tggataaattctataaaatcttttacctgt	Protospacer
   *********** *********    . 

99. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to AF212846 (Lactococcus lactis bacteriophage ul36.1 ORF111a (ORF111a), ORF78b (ORF78b), ORF61b (ORF61b), ORF245 (ORF245), ORF364 (ORF364), ORF235 (ORF235), ORF73 (ORF73), ORF109 (ORF109), ORF79b (ORF79b), ORF174 (ORF174), ORF68c (ORF68c), ORF184 (ORF184), putative dUTPase (ORF139b), ORF118a (ORF118a), and ORF65 (ORF65) genes, complete cds; and ORF120a gene, complete sequence) position: , mismatch: 10, identity: 0.667

attataaattctatcaaatctttttgagaa	CRISPR spacer
tggataaattctataaaatcttttacctgt	Protospacer
   *********** *********    . 

100. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to KX160212 (Lactococcus phage 98101, complete genome) position: , mismatch: 10, identity: 0.667

attataaattctatcaaatctttttgagaa	CRISPR spacer
tggataaattctataaaatcttttacctgt	Protospacer
   *********** *********    . 

101. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to AF212845 (Lactococcus lactis bacteriophage ul36 ORF111a (ORF111a), ORF78a (ORF78a), ORF61a (ORF61a), ORF131 (ORF131), ORF252 (ORF252), putative single stranded binding protein (ORF141), putative replisome organizer (ORF255), ORF241 (ORF241), ORF129 (ORF129), ORF129 (ORF79a), ORF68a (ORF68a), ORF56 (ORF56), ORF68b (ORF68b), ORF237 (ORF237), putative dUTPase (ORF139a), ORF118a (ORF118a), ORF65 (ORF65), and ORF120a (ORF120a) genes, complete cds) position: , mismatch: 10, identity: 0.667

attataaattctatcaaatctttttgagaa	CRISPR spacer
tggataaattctataaaatcttttacctgt	Protospacer
   *********** *********    . 

102. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to MN534316 (Lactococcus phage proPhi2, complete genome) position: , mismatch: 10, identity: 0.667

attataaattctatcaaatctttttgagaa	CRISPR spacer
tggataaattctataaaatcttttacctgt	Protospacer
   *********** *********    . 

103. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to DQ394806 (Lactococcus phage ul36.k1, complete genome) position: , mismatch: 10, identity: 0.667

attataaattctatcaaatctttttgagaa	CRISPR spacer
tggataaattctataaaatcttttacctgt	Protospacer
   *********** *********    . 

104. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to KX160214 (Lactococcus phage 98103, complete genome) position: , mismatch: 10, identity: 0.667

attataaattctatcaaatctttttgagaa	CRISPR spacer
tggataaattctataaaatcttttacctgt	Protospacer
   *********** *********    . 

105. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to MN534317 (Lactococcus phage proPhi4, complete genome) position: , mismatch: 10, identity: 0.667

attataaattctatcaaatctttttgagaa	CRISPR spacer
tggataaattctataaaatcttttacctgt	Protospacer
   *********** *********    . 

106. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to KX160213 (Lactococcus phage 98102, complete genome) position: , mismatch: 10, identity: 0.667

attataaattctatcaaatctttttgagaa	CRISPR spacer
tggataaattctataaaatcttttacctgt	Protospacer
   *********** *********    . 

107. spacer 4.4|1518222|30|NZ_CP049333|PILER-CR matches to NC_004066 (Lactococcus phage ul36, complete genome) position: , mismatch: 10, identity: 0.667

attataaattctatcaaatctttttgagaa	CRISPR spacer
tggataaattctataaaatcttttacctgt	Protospacer
   *********** *********    . 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	209997 : 216318	8	uncultured_virus(33.33%)	NA	NA
DBSCAN-SWA_2	1117571 : 1194056	51	Planktothrix_phage(33.33%)	protease,transposase	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP049333|209997:216318|DBSCAN-SWA
CATGCAATCAGGATTAAGTTTTACAGCAATAGATTTCGAGACAGCTACGGCCAACCAAAATTCCGCCTGTGCCATTGGGCTGGTGGTGGTGGAGCGGGGTATTATCGTTGATGAATTTTATTCGCTGATCCGGCCTCCTCAGAATCAATATATGTGGCAGACAACACGTGTCCACGGTATCAGACCAAAGGATACGGCTGAAGCGCCGACATTTAAAGAATTATTTCCTCGTATTCTTCCATTGATCAATAACCGGATTATGGTTGCGCACAACGAGCTATTTGATAGGGGAGTTTTGCGCAAGACCATGAACTATTATAATCTAGCTTATGATAGTTTGGGTCTCATGGATAAATGGGAGTGTACCTTCAAGATCTATCAGGAGAAGGGTTTTAAGCCAGCACGGCTTAATGCCTGTTGTGAAGTTTTAGGAATTGAGCTTAACCACCATGAGGCACTTTCCGATGCGCGTGCCTGTGCCAATCTATACCTTAGACATGCCGATGTCCCCTCTTTGGCATGATTTTTCGTTAAATCTTCGTATAAAGAAGGTAGCATCATGTTTTAATTTTTATCTTTGGTATAGGTGTACTGCCGTTTTATTATAAATTTTTAATATTCAATTAGACTATGATTACTATTCCAGCCAAGGGCATGCGTATCGGGATTACTTTCAGTGCGTTTGACCTCTTGCACGCGGGGCATATCAAAATGCTTGAAGATGCCAAACGCCAATGCGACTTTTTGATCTGTGGCCTACAGACCGACCCAACATTGGACCGGCCGGAGAAAAACAAGCCGGCACAGACCGTGGTCGAGCGTTACATCCAGCTTAAAGGCTGTAAATATGTGGATCAGATTGTGCCATACGCTACAGAGCAAGATCTGGAGGATGTACTCCGTTCTTTTAATATTGATGTACGTATCGTTGGGGACGAATACCGGGAGAAAAACTTTACCGGGAGGGCATATTGTGAGGAAAAGGGGATTGAGTTATATTTTAATAGCCGGGATCACCGTTTTTCGAGCTCGGGTCTACGCAAGATTGTGGCCAATGCCAATTTGGAAGAGGAATCCATTTTAAAATCAGACCTTTCATCAACAATTTAAAGAAGATAACGAAATGAAGATAGGAATAACTTTCGGTGTATTTGATTTGTTGCACGCCGGCCATATTATGATGTTAGAAGAAGCAAAACGCCATTGTGATTATTTAATCGTTGGCCTGAATACCGATCCTTCGGAGGTGTCTCCGGAAAAAGCGAAGCCTACGCAGACCATCGTAGAACGTTATATCCAATTGGAGGGCTGTCGTTATGTGGATGAGATTATACCCTATGAGACAGAGCAGGATCTTATTGATATGATCAAGGCTTTGCCAATCCATATGCGTATTATTGGCGAGGAGTATCGAGATAAAGATTTTTCTGGCCGTCTGTATTGTGTGGAAGAAAATATCGAGATCTATTATAACAAACGTACACATCGTTTTTCGAGTACGGGACTGCGTAAGGTCGTAGCCGATAAGGAAGCTGAGAAAAAATAATATTATGAGTACAGTTATCCATGTGGTATTAACAGGTGGGGTAGGGAGTCGTTTATGGCCACTTTCACGCAAGAGTTATCCCAAACAATATCTCTCTTTATTCAAAGAGGGTTCCTTGTTTGAAATGACCATTAAGCGCAATCAGTCCTTGTGCGGTCAGGTCATTGTCGTAGGCAATCGTGATAATCATGGTCTGAGCCGGGAGGTGATGGAAAACAATAAGATAGACTATATTGATATTGTTGAAGCTACACCACGTAATACCGCTGCGGCAATTGCCTTTGCAGCCTTTGCAGCTCAGCCGGATGATATTTTGATTGTAACGCCCTCTGATCATGTTATTGTTGGGGAGAAGGAATATGCAGAAGCGATAAAAGCTGGTATTGAAAAAGCGAATAAAGGCTATATCGTTACTTTCGGTATCCATCCGACTCGACCGGAAACGGGTTATGGCTATATTGAATACAAAGATGATAAGGTGTTATCTTTTCGGGAGAAGCCCAATCAGGATACCGCAGAGGATTTTATAGAGCGAGGCAACTTTCTCTGGAATTCAGGGATGTTCTGTTTCCGTGCAGACACTTTTCTAAGTGAATTACAGAATTTCGAACCCAGGGTCTATGCAACGGCATTTAATGCCTGGCAGCATCGCCAGGATGGGGAGCTTGATCTAGCCTTGTCCAAAGAGATCCCATCGATTTCGATTGACTATGCCGTTATGGAGCGATCGAAGAAAATTCGCGTAGTCGCTACGAGTTTTCAATGGTCTGATCTGGGCTCCTTTGAATCCATGTACGATTATCTAAAGCAGACTGGCCATCCAGTTGACGAGAATGGAAATATGGTGATCGGTACGGATGTTTATACTGCTTTTGTCGGCTTACGGGATAGCATTCTGGTGCATACGAAGGATGCCATACTGGTTCTGCAAAAAGAAAAATCTCAGGATGTCAAAAAAATATACAATACATTAGAACGTCATCAGTCCAAGCTGATTGACTAGATTTAAAGAGAAATAAAGACGCCTGATCATTTTTTTGGTCAGGCTGTTTTATTTTCAGGTTGTCCTTGTTATTAAATCTTGTTTTCATAAAACAGCGTTGTTAACACAAAGTTAACGTCTGTATACTGTTGTTTTGAAGGATATTCTCAAATGTCCCCTATTTGTCTCTGGTTGATTTAATGTTGAATTAATAGTAATATCAGATATTTGGTTTTGTTTATTAGCACCTTTGTGTGCAACATCTTAGTCATTTAATTTTAACCAACATATTGATATGGTGATCATAGTTATACTTATTTTTTTATTTTTAGGCGGGTATCTTTTTTGGAGGAAAAGACAGCTGGAACAACGATTTAACCGATGCGTCGGAATGACTGTGAGTTATATGTTTCAGGAGCGTCCCGGGCAATACAGTGGAGATAGAAATGCCAGAAGCGGGGTGTTTGTTTTCAAGGCTGAGCGGAACGATGAGAAACTAAAAAATATTGTTATTCGAAAGGTGAAGCCCTTACATTCGGCTTTGGATGTCAATCTGGAGCAGATTTTAGTGATCCCATTTGAACACAAGGAGATGTCTAATTCGGATGTTTCGGTACGATTTAAAGTGATCAAACGGGGTGCACGGATTGAAGACTTAAAAGGTAAGCGTGTGAGTATTTCTGGCGTATTAAATTATGAACAACGCAGGGCTGAGCCTTTTACTGCCACGTTGCCAATAATGGATTTGTATCAACAAGTTCGGACGGATTAAGGGTGAGCTCTTCGTTTTTATATAATTATAAGTGGGCACTTTGTTACAAAATGTCCACATTTTTGTCTTTAAAAGTAGATGTTCCACGTGAATTTTCATGTTTTAGTCTTGCTAACTAGGTGTTTAGGATAACTTATGTTTATTTGTCTAGGTGAAGGTAATATTAACAATTTCTTTATTTGCGGAAATAAATTGTATTGAGTACTTTTGTTACTCAATTTAGGCTAAACCATGCTGGATTCGTTGATTACTTCCAAAACCCGACTCAAATTGCTGATCAAATTTTTTGTTTCGGCAAGTAATCGTGGTTATTTACGTGGATTAGCTGATGAATTTAAAGAATCCACGAATTCTATTCGCAAAGAGCTCAATCAATTGACTGAAGCCGGTTATCTTATACGTGAAGAAAGTGATAATAAAATATTCTATCGGGTGAATGTTCACCACTCATTATTTTCCTCTCTCAGCGGATTAATTCATAAATTCTTGGGAATCGAGGTTTTTGTTGATAAAGTTCTAGAAAGAGCAGGTGATGTTGAGGAAGTAGCATTGTTAGGAGATTATGCACAGGGGATAGATTCTGGCCATATTGAGGTATTGATAAAAGGGAATAATCTTGATAAAGGTTATTTAGAGCAAGCCTCTATTAAAGCTGGCACTATAGTTGATAAAAAGGTCACCGTATATACAAATTGTTCAAATACTGTTCATGGGAAAATTGTGCTTTATCAAAAAAAAGAAGTACTATGAATTTATATAAATGAAATGTTGATTTTTTTGATCGAATGAATTTAGAATAAACAAAAGATTATAAAATAAAAAATATGTTGCAAAATAAATCTATTTTAATAACCGGAGGTACTGGTTCTTTGGGTAAAGCGTTAACCAAGCATATACTTGAAAACTACAAAGATGTCAAAAGATTGGTGATCTTTTCAAGAGATGAGCAGAAACAATTTCAAATGGCTCAAGACTATCCTGCTGACAGGTTTCCCCAAATCCGTTTTTTTATCGGTGATGTTCGAGATAGAGAGCGTCTTATCAGAGCAATGAAAGGTATTGATTATGTCATCCATGCTGCTGCAATGAAACATGTGCCGATTGCCGAGTATAATCCTGATGAGTGCGTTAAGACTAATATACACGGTGCACAAAATGTAATTGATGCTTGTTTCGCTACTGAAGTAGAGAGAGTTGTCGCACTATCTACAGACAAAGCCTGTGCGCCGATTAACCTATATGGTGCAACTAAATTAGCTTCAGACAAACTGTTCGTTGCAGCAAATAACATTCGTGGAAATAATCCTATTCGCTTTTCAGTTGTGAGGTATGGAAACGTTATGGGGTCAAATGGTTCAGTTATTCCTTTTTTTATTAAAAAGAAAAAGGAAGGCAAATTGCCTATTACAGACTCCAATATGACTCGATTCAATATTAGTTTACAGGGCGGGGTAGATATGGTTATGCATGCGTTATTTAACGCTTGGGGAGGAGAGATTTTTATTCCCAAAATACCTTCTTATAAAATTACAGATGTTGCTACTGCAATAGGTCCAGAATGTGAACATCTTGTTATAGGAATCAGACCAGGTGAAAAAGTACATGAAGAGATGATTACTCCTTCCGATTCATTTTATACTTATGATTTAGGAAAGTATTATACAATTTTACCTTCAACACCAAAATGGGATCTAAATACGTTCCTATCAGAGTTTAATGGTTCGAAAGTGGCGGAAGGATTTGCTTATAATTCGGGAGACAATACAGATTGGGAAACTGTGGAGAGTCTTAGGACATTAATTAAGGAACATGTTGATTCAACCTTTGAAGTATAACGATGGAAAACAAGATTATTCCTTACGGAAAACAAAATATAACAGAAGAGGATATTGAGGTTGTGATTGAGACATTGAAATCCGATTACTTAACACAGGGGCCCAAAATTAAAGAGTTTGAAGATAATTTTGCTAAATATGTGAACGCAAAATATGCAGTGGCGCTTGCAAATGGCACTGCAGCGCTCCATCTATGTGCGCTAGCTTTGGACGTACAACCTGGTGATAAAGTTATTACTACTCCCATTACTTTTGCTGCTTCGGCAAACTGTATTAGGTATTGTGGAGGAGAGGTTGTATTTGGTGATATTGATCCTGATACCTATCTCTTGGATATCAATTCGGTGCGTTCTCTGCTTGAGGCTGCTCCAAAAGGGACTTATAAAGGTATAATTCCTGTTGATTTTGCTGGGAGAGCTGTTAATTTAGAGGAATTCAAAGCGTTGGCAAAAGAATATGATCTTTGGATTATAGAGGATGCTTGTCACGCACCTGGAGGATATTTCATCGATAGCAAGGGTGAGCAGCAATATTGTGGCAATGGACAATTTGCGGAACTAGCCATTTTTTCTTTCCATCCTGTCAAACATATAGCTTCTGGAGAAGGCGGTATGATTACAACAAATAATGAAGAGTTATATAAAAGGCTTCTGAAATTACGAACACATGGAATAGTGAAACAAGATGATTTGTACACAAATTCTATAGAATTTGCTGGAGGTATAGAATCATATCCATTATGGTATATGGAAATGCAAGCATTAGGATATAATTATAGAATTACTGATTTTCAGGCAGCTTTAGGTAATAATCAATTAAAGAGAGCGGATAGCGGTCTTGAAACCAGAAGATCTATTGCAAGTCGTTATAAGCAAGCATTTTCTGGTAAGAGTTATGTCAAGGGTCAATCAGGAGTGGTAGATGGACATGCTTATCACCTATATATTTTAGAAGTAGATGATCGTTTAGGCCTTTATAATTATTTGAGAACAAAAAATATTTTCGCTCAAATACATTATATTCCCTGTCATTTAATGCCATACTATCGCGAATTTGGTTGGAAGGAAGGAGATAGAGTAGCTTCTGAAACGTATTATAAGCACTGCATTAGCTTACCGATGTATCCGACATTACCAAAGGAAGAATTGGATTATGTAATCGAAGCTATTGATGAATATTACAAATAA

Protein sequences of DBSCAN-SWA_1

>NZ_CP049333|209997:216318|209997_210519_+|WP_165305250.1|DBSCAN-SWA
MQSGLSFTAIDFETATANQNSACAIGLVVVERGIIVDEFYSLIRPPQNQYMWQTTRVHGIRPKDTAEAPTFKELFPRILPLINNRIMVAHNELFDRGVLRKTMNYYNLAYDSLGLMDKWECTFKIYQEKGFKPARLNACCEVLGIELNHHEALSDARACANLYLRHADVPSLA
>NZ_CP049333|209997:216318|214120_215131_+|WP_165305254.1|DBSCAN-SWA
MLQNKSILITGGTGSLGKALTKHILENYKDVKRLVIFSRDEQKQFQMAQDYPADRFPQIRFFIGDVRDRERLIRAMKGIDYVIHAAAMKHVPIAEYNPDECVKTNIHGAQNVIDACFATEVERVVALSTDKACAPINLYGATKLASDKLFVAANNIRGNNPIRFSVVRYGNVMGSNGSVIPFFIKKKKEGKLPITDSNMTRFNISLQGGVDMVMHALFNAWGGEIFIPKIPSYKITDVATAIGPECEHLVIGIRPGEKVHEEMITPSDSFYTYDLGKYYTILPSTPKWDLNTFLSEFNGSKVAEGFAYNSGDNTDWETVESLRTLIKEHVDSTFEV
>NZ_CP049333|209997:216318|215133_216318_+|WP_165305255.1|DBSCAN-SWA
MENKIIPYGKQNITEEDIEVVIETLKSDYLTQGPKIKEFEDNFAKYVNAKYAVALANGTAALHLCALALDVQPGDKVITTPITFAASANCIRYCGGEVVFGDIDPDTYLLDINSVRSLLEAAPKGTYKGIIPVDFAGRAVNLEEFKALAKEYDLWIIEDACHAPGGYFIDSKGEQQYCGNGQFAELAIFSFHPVKHIASGEGGMITTNNEELYKRLLKLRTHGIVKQDDLYTNSIEFAGGIESYPLWYMEMQALGYNYRITDFQAALGNNQLKRADSGLETRRSIASRYKQAFSGKSYVKGQSGVVDGHAYHLYILEVDDRLGLYNYLRTKNIFAQIHYIPCHLMPYYREFGWKEGDRVASETYYKHCISLPMYPTLPKEELDYVIEAIDEYYK
>NZ_CP049333|209997:216318|210650_211106_+|WP_108635496.1|DBSCAN-SWA
MRIGITFSAFDLLHAGHIKMLEDAKRQCDFLICGLQTDPTLDRPEKNKPAQTVVERYIQLKGCKYVDQIVPYATEQDLEDVLRSFNIDVRIVGDEYREKNFTGRAYCEEKGIELYFNSRDHRFSSSGLRKIVANANLEEESILKSDLSSTI
>NZ_CP049333|209997:216318|211119_211542_+|WP_121127107.1|DBSCAN-SWA
MKIGITFGVFDLLHAGHIMMLEEAKRHCDYLIVGLNTDPSEVSPEKAKPTQTIVERYIQLEGCRYVDEIIPYETEQDLIDMIKALPIHMRIIGEEYRDKDFSGRLYCVEENIEIYYNKRTHRFSSTGLRKVVADKEAEKK
>NZ_CP049333|209997:216318|211546_212545_+|WP_165305251.1|DBSCAN-SWA
MSTVIHVVLTGGVGSRLWPLSRKSYPKQYLSLFKEGSLFEMTIKRNQSLCGQVIVVGNRDNHGLSREVMENNKIDYIDIVEATPRNTAAAIAFAAFAAQPDDILIVTPSDHVIVGEKEYAEAIKAGIEKANKGYIVTFGIHPTRPETGYGYIEYKDDKVLSFREKPNQDTAEDFIERGNFLWNSGMFCFRADTFLSELQNFEPRVYATAFNAWQHRQDGELDLALSKEIPSISIDYAVMERSKKIRVVATSFQWSDLGSFESMYDYLKQTGHPVDENGNMVIGTDVYTAFVGLRDSILVHTKDAILVLQKEKSQDVKKIYNTLERHQSKLID
>NZ_CP049333|209997:216318|213527_214046_+|WP_165305253.1|DBSCAN-SWA
MLDSLITSKTRLKLLIKFFVSASNRGYLRGLADEFKESTNSIRKELNQLTEAGYLIREESDNKIFYRVNVHHSLFSSLSGLIHKFLGIEVFVDKVLERAGDVEEVALLGDYAQGIDSGHIEVLIKGNNLDKGYLEQASIKAGTIVDKKVTVYTNCSNTVHGKIVLYQKKEVL
>NZ_CP049333|209997:216318|212915_213296_+|WP_165305252.1|DBSCAN-SWA
MTVSYMFQERPGQYSGDRNARSGVFVFKAERNDEKLKNIVIRKVKPLHSALDVNLEQILVIPFEHKEMSNSDVSVRFKVIKRGARIEDLKGKRVSISGVLNYEQRRAEPFTATLPIMDLYQQVRTD

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_165305250.1|209997_210519_+	3'-5' exonuclease	M1PFD8	Streptococcus_phage	1.0e-22	38.9
WP_108635496.1|210650_211106_+	adenylyltransferase/cytidyltransferase family protein	A0A218MN49	uncultured_virus	2.2e-37	54.9
WP_121127107.1|211119_211542_+	adenylyltransferase/cytidyltransferase family protein	A0A218MN49	uncultured_virus	2.1e-34	48.2
WP_165305251.1|211546_212545_+	NTP transferase domain-containing protein	A0A1V0SH58	Hokovirus	5.2e-31	31.0
WP_165305252.1|212915_213296_+	hypothetical protein	NA	NA	NA	NA
WP_165305253.1|213527_214046_+	ArsR family transcriptional regulator	NA	NA	NA	NA
WP_165305254.1|214120_215131_+	UDP-N-acetylglucosamine 4,6-dehydratase (inverting)	A0A1V0SAI8	Catovirus	2.7e-43	37.2
WP_165305255.1|215133_216318_+	UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine transaminase	A0A2K9L0G1	Tupanvirus	5.9e-34	30.3

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP049333|1117571:1194056|DBSCAN-SWA
TATCATCAACGATGTTCCGCCGGAAAATAATGCCTCCGAAAGAGCTATCCGTAATATAAAAGTGAAACAAAAGATCTCAGGAATGTTTAAATCTGCTAAAGGAGCACAGAATTATGCAATCATTCATTCTATTACTGACACCTGCAACAAAAATCAGCAGAACATCTTAAATGCGTTCCGGACTATTGAAGCGACATAACCTGAGTGGTTACGACCTGAGTTACAAATAGAAAATGGAAATTTTCATTAATGATAATGTTTTAGGTTGTTTTCATATTGAGAAAATGCTACACTTTTGTGTAGTATTTTTCTGTTTTTATTTGGTAAAATTAAAAAAATAACTATATTGATTTTAATTAAATTATACAATCTCAACTTAAAGGGATTTTTTTTAAATTTAAATGCGTACTAATTATAAATAACTATTTATTTTACTTACTTATAAGGACCAGCATGAGGCTATTTATATTTTTAGTGTTTTAAAATAAATTATTGTCTAGTTTCTTAATTTGTGTGCTAAATATCTTTTGGATAATATAGAATTTTTTTATGACTTATATTTAGGGTTAAAATATAAATCGTTTTCAATTATATATAATTAGTGTAAAACGATAATAAGATTTTTATAGAAAATCTTCGATCGATTGCAAACGAATTGAGGAAACAGCATGCTCGCTGTCAAAACTGTAGCCTCCAATCTATATCCTGGAGTGTAAGGATATTATAAACTTAAATAACACAAAAATGAAAAAGATCACGTTAAAATCAATTAAAAATCAGGAAATCCTCTCTCGTGATGAATTGAAAAAAATAACCGGTGGAAGTGATGGCAGTGGTGCAGTTGGATGCGCTGGCAAAAGAGAATGGGATTCTTGTACACAATCTAACGGAAATATAGGGAAATGTCAATACTTGCCCTTCAATTCTGGCTTAGTTTGTTTTAGAAATTAGTTTATACTAAAAGTATAGCCAATAGTTTTCTATTGGCTATACAAATTAAGAATAGGATGAAAAATGCAATTCGTATTCAAGTAATTTTATGGTCTTTAATTTGCTTCGTTATCGTTAACGTAAATGCCCAAAATAATTTGGAGAACATTGCCGAGAGTTTTGGAGATTCTTATTTTAGGTTTGAAGTAAGGGACAATGCAAATAAAAAAGCTTTATCGCTCAAGTTGACCCTAACGAGTAATTTGACGAGCTATTATGATATAAATATTCCCATTCAGGGAAATTTAGATACCCTTTTAAAAATACCGTCATTTAAGATGACCTCAGCAATTTTGAAAATAGACAGTATCGAGAGGTATATATTTTTCTTTCCAAATGACACTACTAAAGTAATTTTTAAATTCGATTCCAACGAAAGTTCTGATATCCAATATAAAGGCCCTTACGAAACGATATTTCGTGAAACAAAAGCCATCCAAAACTTATTTACCAACTTATTCAATGGGGGAATATCGTCTAATGACTATGTATTCGAACCCAACGCTTATCGTGATCGCGCATTGATATCAATGAAAGAAAAGATAGATAAGATTAAAAATACAACATTATCGATGGATTCAAAAATATGCCTAGATAGAACATTTGCAGCAGTATATGCAAAAATGTTCTTATTAGATCCGAATAATGGAATGTATATTGATAATGTTGATGCTGGGATGGACAAAGAGAGGGCTAAAATAAAAAATAGGATTAATTTAGATTATTACACTTTTTTAAAAGATTTAGATCTCAATAATAAAGATTATCTACTATCAAACTATTATAATGAATTAACAAAATCTTTATTGGCCGATAGTGTGCTAGACTTACCCAAAACAGATCAAATTTCATCAAAAGATTGGATGAAGACAGCAACGACAATACTCGCGCCGCTGTTGGGATATTCTGAGGGCTATTTTTATAATATTATGTTGGCAAATGCTTATTTGGATCAAATCGCTAGAGGTAAATTACTTTCAGATCGACAATCTAAAGATATTGTTGGATATTTTAATGATAAATCATTTTCTGATTATTTATTATATCAAAATAATATAAATAAAATTAGGATTACAAATGATAAAGGACGAGTTTATGATTGGTCTAATCTAGACAAGATTAACATACTCTCAGAAATCATACAAAAATATCCTTCTAAAACTGTAGCCATAGACTTTTGGGCAACCTGGTGCGCGCCCTGTTTAACCGCCATGGATGAAATTAAGCCAATAAAGGAAAAATATACTGATGTCGTTTTTGTCTATATTACAGATATGTCATCTTCTAGAACTTTGTGGAATAATCAAGTCAAAAATATAGCAGGTGATCATTTTTATCTTTCATCTAAACAAATGGAGGAGCTTCAAAGGCAAATGAATTTTTCATCGATCCCAACTTATTTAATTTACAATACGAAAGGTGAATTGATGAATCAAATGACAGGGTTTCCTGGGGTAAAAAAATTTGAAGAAATTCTGAGGGATACACAAAAGTAAACTTAATTAACATCTGATTGACAGTTTTGTAGTTTATTACTTAGTAATTTATGGAGAAAAAGTATGACTTATTTATCTAAGTATATGACAAAAAATTAAATATCCTCAATTCCATCATATTAAAACCGGTTAAAAGGAATCTAGATAAATAATCCAAACCATATTTGAATACACTAACAGACCTTCTGCCATGTGTTTTATTTTTTATCTTTTCAGTATTCTCGTCAATAAAATCGCCCATGCGATAGCACCAGACGAATGCGATCATGGTTAAAAGAAACAATTTTTCCAGTCTTTCCAAATCGGCCGCATTCATATCTTCTCTAAAATGGCCTCGTAAAACCGTTAACAATCCTGTATCTTTATCGCTTGGACTGGTCTTTATTTATAAGTAATTATCTCAAAAAAAATTTATTAACATAATGAATGTCAGTTTATTATACAAATTTAAAACCACTAACTTTTACTGCTTTATTCCTCTATCTCTTTCAGTTCGAGATGTCCGCAGAGTTCGAGCATCATTTTTGCCGGATCCGTGTCGATGGCCAAGGCAATCAAGTACATTTCATCCAAACGTAATTTAGCGGTCTCGGTCATGGTTAATTCATTGATCCTTGCCTTACTTAATCCTGTTTTGCGGGCAATCTGAGATTTATTTACAGATTTCTTCGCTAAAAATTCGCCTAATTTTGTCATCCTTTTTTTTAATAATCTGTCCTTTTGTATAGATAAATATATACAATGTTATTTTTATTTATACAAATGTTTTTGTTTTTAGAATATATTCTGTTCTTTTGTATTGATAATCTATATAAATGTTATGAGTGATAAATTTAAACCTAGCACGAAAGTGTATAAAAGGAAATGTCAAGAGATAGAAATATTGATATTTTACCGGATGATATTGCACCGTATCTCGCGGCATTTGTCGCCTGAGGAAGTTTCTTTTTTAATGGGTAAGCCATTGGATTTTATGACTAAAATTGAGACATTCAGGATTAAGCAAATTTCTATGCACGATGTATTTGTCATGAATGATGTATTGGCTATAAATAACCTAGATACTATGGTGCATATGGGTGTTAAAATATCGTCAGCGGAGAAAAGATACGAATTGCATATGACAAAACTGGCTGACCGGGTTATTTACCGGCTATATAAAGTTGATGAGGAGCAAGATCAGCGAGTAATCGAATTTAAATTAATAGACATTCGTCACGATATTGATCCTTATGAAAGTTCTACAGCGGATGAAGTGGAAAAGATAGCGGCTTTTTTGGAGGAGACAATTGATGCTGGATATTTTAACGAGGAAAAACAACCTGACGAGGTGCATAAGTTATGTTGCGAGAAGTTGGAGAGCTATGTACGACCTAAAAATCTGATGAAGGTGCTCAATGATCTGCTCAGTCTGTCTGGCGAACGCAAAATTGTTCAGAAAGAATCTCCATATGGGTTTGCCTATGTTTTAGCGGCTCACACGGAATCGACTGAAAAGAAATAAGCAATTTTTAACTGTTCACATCGAACAGCTAAAAATTGTTACAAAGATCCTAAGCCGTAGGTACACCAATTATAACTTCCATTCCCTTTAGCTTAATAACAGTTTGCACTATTTAAACTTCGCACACCTACGGCTTATTTATTCGTCCCGTAAACTATTGACGGGATTGATGCGGGCTGTCCGGAATATCCGGACAGCAATAATCGCTAAAGTTGTCAAACCGATAAACAATCCCGTGAAAACAAATAGGGCAATCGGAACATCAATATGGTAGTAGAAATTTTCCAACCATTTGTGCGTAAACCACCATGCTGTGGGAAAAGCAATTAGAATAGCGATCAGCAGGAGCACGATAAAGGATCTGGAAATCATATAGGTGATCGTATTTACTGAAGCCCCCAATACTTTACGGATACCGATTTCTTTTACCCGTCGTTCTAGCGTATAAATGGCAATGGCTACGATCCCTAAGATAGCAATCAGCATACTGGCCCCCGTAAAAAGTGCCAATTGCTGGTACTGTTTTTTCTCTTTGTTATATTGATGCTGTACCTGATCTTCCTGCCAGTTGATCTGCGCGATCCGGTTAGGGAAAAATTTGTTCCAGGTACTGTTTACCAAGGCTAAAGCTTCCTTTTTCTTGCCTTCTTCTACGCGGATAAGCATGCAGCCGCCTTCCCATTCCTTTTGTGCCTTAATCGCAAAAGGGCCGATCGGAAACTTTAAACTTGCTCCGTTAAACTCTTTAAATACGCCCACCGGTGTATTTTTTAGAGGCTCGTTGCTCCTATTGAGTTTTAAAGATAGCCGCTGGGCGGTGCCTTCGGAAATGAGCATGTTTGTAAAGACCGGTTGTCCATTGTGTACCGAATCCGTAAATGGTCTGTCCATTGCATAGTCCGCACTCAAAGGCCGGCCGTCAAGAAGCTTTATGCCCATTGTTTTGATGTAATCATAGTCCGCATAAACAAATACAACCGCGAGATCTTCGTTCGGATTATCGGGGTCTTTTACTGTTTTAAAATCCACACTCCCACTAAAGGGAGTCCAACCTGTGAGGCTGACCGATGAGATGTATGAATTTTTTAATAGCTCCTGTTTGAAAGCCTGATCCTTTCCTTCCCAGGAGGTATAGTTGATGGCCAAAAGATTTTTAGGTTCGTAGCCAAGATCTTTGCTGTACAGGTAATTCAATTGCGCCCGCATGGACATCATACAGATCGCTACGACAATGGCAATGGCAAACTGGATAACAACCAGTACTTTGGTAAATGCCATATTGAGCGGAAGTCTGAAGAAAGAAAGCTGCCTCCGAAGTTCCAATGATGGCTGCGTTTTTGATAGAGACAATGCCGTAGGTAAGCTGCACAGCCAGCCCAGAAGGATCCAGGTGGATAATAATCCAACAAACATTAATAAGGAATGCTGGTAGCTCATCGTCAATGGATGTTCTAAATAATGTTCAAATGCCGGGCTGATAAGCACATAACCAAAAAATGCAATCAGAAAAGAGCCGGCAAAGAGTATGGTACTCTCCAGGCCCATTTGCATAATCAGATTCTTTCGGCTTGCACCCAATACTTTGCGGATTCCTATCTGCTGTGCGCGTTTTAAGGCATGGGCAAAGCTCAGGTTGATGTAATTGATACTGACCAATACAAGGATCAAGAGCGCTATTCCAGCCAGCAGATAAATATCCTGCATCGGATTCTCCCATCCTGTAATACTTAGTAAGTGTATGTCTTTGATGGGCTCAATGATAAGATTGTGTCCTTTCGCCCAGTCATTCAGTTTCTGTGCATTGTACCATTTGTTTATTTTAGTTGAAAAGCTGTTAATGTCAGTTGTGCTTTTGAGTAATAGAAGCTGTGTTTGCAATGAACCAGTCTCTGCCGGATTGAATTCATTGACCTTAGGCATCAGCACGAGGGCTTCTGCCTGAAAGGAAGAATTATGGGGCATATCCTCAATAATGGCATTGACATAATAAGCTTCGGGCTCCCCTTCTTGTGGTTTATTGTAGAATGTGCTGCCGAGCACGTCTTTTCCGCCGAAGTGTTTTTGTACAGCGGAGGCTGTCAATGTGATATTTTTTGCTCCGGCAATGACTTGTTTCGGATTTCCAGCGATTATTTTTGCGTCAAAAAGATTGAAAAAACCACTGTCAATTTCCAGCGTATTGATTTCGGCTAGTCGCTTCGAGCGCTTGTTTATGGTTAATTTTGGTGAAAATGAATTGATTGAAGTATAGCCAAGCACCTCTGGAAAATTAGCTTTTAATGTGGCCGAGATACCTTCGGGAGCTCCTGAAATATTGTTTGTGACACCTTCCTTTGTTTCTTTGGGCACTATTCGCATTCGGTAAAGCTCATTGGAGTTGCTCCATTGTCTGTCGTAAGAAAGTTCATCAACGACAAGTGAACTGATCAACATAAATACGAACAAAGCAATGGTTAACCCAACGAGGTTTGATAGCGAATAGATCCGATTGTGTGTCAATGTCCGCCAGGCGGTTTTAAGATGGTTCTTTATCATACTGTTTATATGGATTGGTTTATGATATTATTCATCCCTTAATTTTTCGACCGGATTAAACCGGGTGGCCCGAAATACGATGAAGCCCACCAGCAGACCCAGCATGCTCAGCAGTATGCCCAGTGGCAACAGGTAGGTGAATGCATTGATTTCTATTCGGATGATATAGTTCTGTAGCCAGTGTTGCATCAGCATATAGCTTGATGGGACTGTTACCAAAATCGCCAACAAAAATATGCCATAGTACTCTTTCGAAAATAACAGCATCAAATGTGCTAAGGAGGCGCCCAGCACTTTGCGGATGCCTACTTCCTTGTTACGGAGATGAATCGATAGGGAGATCAGGCCGGTTAATCCCAACACGACGATCAAAAGTGAAACCGCGCTCGCGATCTGCGCCGCCCGGTGCAGTTGCAGTTCCGTTTCGTATAAACCTTTGATGCGGTCATCCATAAATTGATATTTAAATGGCGCATCCGGCATCAATTGTTTCCATTTCTTTTCCAGTCCTTGCACGGCGCTGGACAGTTGACCCGGTTTTAAACGGATACTTAGGTATCGGTATTGGAAACTTTCACGGATATCTGTCCAGGCGATCGCCGGAGATGCCTGATGGAGAGAATTTGCGACAAAGTTGTCGGTAACCCCTACAATGGTCATCTTATCTTTTGGATCATTTAGTGCGATCTGCTGACCGATCGTACTTTGAGCATCACTGAAACCAAAATCTTCCATGGCTTTTTTGTTGATAACAACGGGTCGATTAGTGGTACCGGTCACCGCATTTTTCGGTAAAAAGGTGCCGGCCAATAAGGGGATTTCATAGGTTTCCAGAAAATAACCGTCACTGGTAATGCGTTGTACCTGTACGTCCGTGTCGTTGTTATTGCCAAAAGCCGGTTGCATATTGAAGCCTAATAACCCAGGGGTTTCATAGGAAAGACTCACGGACTTAACCGCTGATTCCTGCAGCAGCTCATGCCGGATGGTCTCCATTTTCCGGATACCATTTTCAGACCAGTCCCTTGGTGCCTGTACCGTCAATAGATAATCCTTGTTGTATCCTAAATTACTGTTTATGAATAGATTGACCTGTTTGGAGATAATCAGGGTACAGACCAGGAGGAGCAGGGCAACGGCAAACTGAAAGAACAGTAGCACTTTTCGAATCAATTGCTTGTCACCCAATGCGGAGAACTGATTTTTTACCGAGGGAAGTATCTTGATATTGGACAGTTTAATTGCCGGATATAGTCCCGCCAGCATACCGACCACTATAGTCAACAGGCCTAATAAACCAAAAAAATAGCCCGGTAAATTGATCAGAGACGGCAGCTCGCGCATCAGCACATGTGCAAACAAAGGGTGTACCATGCAATACATGGGTAGACTGATCAAGGCTGCAATAGCTACGATAAGAATATACTCTGTCAGCAATTGTCTTACCAATTGTAATCTGGAAGAACCCATAATCTTGCGCACACCGATTTCCTTCAATCGTGTAATATGCTGTGCAATACTAAAATTGATAAAGTTGATGATGGCCATGACCAGGATAAAAATGGCTATCCAGATTAACGTCTGAATCATCTTGCGGACAGCGCCCTGATTATCATCTAAATAATAGCTTTTCAACGGCTTTAGGTCGGGGCTGTATTGGCTGGCGAATTCCTGATCGGTGTTTTTATGCACCAGCGTTTGAATCGCCGCATCCAGTTGTTGTGTCGTCACCCCGGCTTTCAATTCGAGGTAACCTGCAATGTAAGGATTATTCCAGTTATCCACGGATCTGCCGAAGTATTGTTCGTTGGCAATGGGCAGGAAGATATCGGAATGCATATCCTTTGTTAGATCCATGACCGCATTTTGTACGGTAGTTTTTATAATGGCAGTAATTTCAAAATCATGTTTTTCGCCTTTGAAATTTTTAATCTGCAAGGTTTTTCCCAGAACATTTATGTTTCCAAAATATTTTAAGGCGGCCCGGTCAGTGATCACGACAGAAAAGGGGTTGTTCAGCGCGGTCTTGGGATTGCCCGCTAAAAGCTCAAAACCAAACATGGTCAAAAGGCTAGGATCTCCGAGTGCCATTCCTTCTTCATGGATCGTAGCACCATTGGCGATAATACCTGTCAATCCATCGATACGATAATAGTTGGCCACCAAATCCGGATAGTCTTCATAGAGGGCTTTGGGTAGTGCTCCAATCGTGGTCAAATTGATTCCAAAACCTTCCTTCTTATACTTGCTCTGTAATAAAAATTGCTGATCTATATTTTTGATTTTACTATTTACCCGATGAACATCCCACATATAGGCCCCGACCAGCAGTAAAAAGGTAATGCCAAGAGTCAATCCGATCAGGTTGATCAGGTTTTGAATTTTCTTCTTTCGAATATTCCGCCAGGCAATCTTGAAGTTTGTAAAAGTCATTGTCACTTGTATAAGGGTTATTTCCGTCACCGCATAAAGACCGGATGCCAGCTTCGGTTTTCGCTAGTTTTTGTATCCTAATACAAATCCTTAGCCAAATAGGTATGTTGTTGTGAGTGAATGTATTAATATGCTTTCAGTTGAAGGGACTGTTCGATTTCGGACAGTCATTGTACAGCGGTGAACACCTTGATATCGTTGATTTTCTGGACGAATAACAAATAATAAAATAGGTGAACAGGAAAAACTCATTGGAAAAATTCAATAGCAGAGAAGCGATCGGCGGTATCGGATGAACAGTTTCATTTTATAGATTAGACACTGTAATTTTCAATCGTGAAAAAGCTTTTTACCAGTGTGTTATTTCCAGTCCTCAATTTGAAAAGTGACCTTGCTCATTAGGAAGAGGAATAGGAAAACGAAATGTTCGGTTCTCTCAATTTGATTTGTGCTATGCCTAATTTGGAAGCGCCGATCGCTTATTGGATTTGCAGAAACGCTATTTGAATATGCTATTTGTTTAATTAGCGAAACGCAGTATCTTCATCGCATTCAGCTTCCGCTCCATTGAAAAATTGAATACCCAATATGTAATTGGCAGCCGCTCAATTGCTTTCTGTTTTTTCGGGTCAAGACTTTGCGCAGTTTCAAGTGTATTTTTCAAAATATAATATGTTTTTTGATTTTTCAAATTATCCTAGGGCGGCTGATACAGGATCTTTCTATTTCGGAAAAGGATGTTTATCGGTCCATAACGCAATATTTACTACAGATTGCTGTTCGAAATCAACTAAAATAAGGGGTAAAATTGTCCCAAAATCTTTTTTGTACTTCCTGCATTTTGGGACAATTTTACCCCTGTCTCCGAGCCTCCTGACTGTATCTTTGCTTATGGAAATAATTTTATCTGAAACATTTAATTTTAAAAAAGATGAGTCAAGTTACACTTAATGAAAGAGGGCATAAAGATGCCGGGTTAATGCAGGTGGCGGAACAGGTGTTGAGCAAAATGGCTGCTGAAACCGAACTGTTTGCAGCCCCTGTACCCGCATTGTCAATTTTGGAGGAAGCGCTCGTTGCATTCCGGAATGCCGCAACGGAAGCCTATTATCGCGACACACGTGCTATACTGATCCGTAATCAAAAAAGAGCTGAACTGGCGTACGTATTGAAAGAACTGGCTAAATATGTAGATACGATCGCCAATGCTGATCCGACGATTATTTTAGCTGCCGGTTATGCTGTCAGAAAATCCAAAACTTCTTATGGAGGAGTGGTTCCCAAAGTGGAGCGACTAATCGCCCGTCCCGAAGAGGTGGGTAGTGGACGCGTGAAGCTAAAAACACAACGATGGCGGGGGGCACGCATGTATCAGTATCAGTTCCGCATCAAAGGTCAAAATGTAGACTGGAGCACACAGCTCTGTTCTAAAAGCAGCTGTATTATCGATGGGTTGGAGTCCTTTCGTGAATATGAATTTAGGGTCTCCTATATCGGAATAGACCCGACTCCAAATTATAGTGATATCATCAGCAGTTATGTACTTTAGACAAACCTTATTCGAATACGGAGCATCGGAAAGGAGTGTCTGTTCAAATCCCAGCATTTTCGCTGTAATTTGTTGACAGCTTCCTTTCCTATTCGTCCCGTAAACTATCAACAGGATTGGATGTGGCCGCTTTTATTGCTTGGAGGGATACCACGGCAATCGTTAACATAAGTCCAACACAGAAAGCGGATGCAAAGATCCACCAGCCCATACTGATCCGAAAAGGGAAATTGTCCAGCCAGCGGTTCATAAGATAATACGCAAGTGGTGTAGCAAGTAAAAAAGCAATTGTTATCCATTTAAAGAAATCTTGTGACAACAATACAATAATACCTGTTACCGAAGAACCTAACACTTTTCGGATTCCGATTTCTTTTGTCCGTTTTAGGATGTTAATGGAGAGCAGTCCCAAAAAACCGAGCATACTGATGCTTATCGCGACGATAACGGCGATCCAGATTAGTTTTTCCAGTAATACTTCTTTCTTGTAGAGCTGAGCAATCTGCTGATCATAGAATTTGTATTGGAACACTTCATCGGGATACCAATTTTTCCATTGTTGCTCCAGATCTTTCACGAGCAGTTGGTGATCGGTACCCTTCAGTTTAATCGCTACATTTTTTAACCGCGTTTCATTATACCCAATTACGGTAGGGGAGATGGGCTCGTTCAGCGAATTGGTGCTAAAGTCCGCAACAACTCCTACAATTGTTCCTACTTGTTCTTCGTTCAGCCCACCGGCGTTTAAAGACTTGCCGATAATATCATTAGGATCTTTATAGCCCAATGCGGTAGCCATATTTTGATTGATCAGAAATTCAGGTTTCTGGGGATTGTCGTTGAAATTTTTTCCTGCCAATAATTTGATGTTAAAAGTGCTGATATAAGCAGAATCCCCGATAGCGTATCGGGCAGGCCATTTTTCCCATTCTGTTCTGTTGTCAAACTGGATGGTTCCGCCCCATACCTTTTCAGATGAAGGTGGATTATCGCTAAAAGTGTACGATTGAACATCGGTTCTATTGCTGATGAAATGAGCGATTTTCGCTTTTGATTGGATCATTTTTTTTGTGAACGGAAGCAGGATAACCTGCTCCCTGCTGAATCCAATATCTGTGTTTTTGAGGTGATTTACCTGTAAGACAATAACAAAAGTGGCGATCAGCAGCGTCATGGCGATCATATTCTGAAAAACAATAAGCGTTTTGCGACTAAAGTTCCAGGGGCCTATGGTCAGCTTTTTCAATGCCTGCTGGATGTCCATCTTATTGACAAAAATGAGGGGATAGATGGAGGTCAACAGGCTCGTTAAAACCCAGATGATACCAATGATAGCTATAAATGACCGAGGATGGACAATCTGTACAGGTTCATGTGGAAAAAGAGCCTGGTTTGCCCAATTGGAAAAGATCAGCAATAAAACTAAAGCGAAGATAATAGCAGCAGCGGTCAGGATCAGGGTTTCGATCAGAAACTGAATGTAGAGTTGCCTTTTGGAACAACCCAGTACCTTTCTCACGCCCATTTCTACACTGCGGTTCATTTGTCTGGCAAAGGTGATGTTGCTGTAATTGACCAATGCCATGATACTGACTCCGATGGCAATTGCGACCAGGATACTCAGAAGTGTACGTTGTGTTCCCTTTCCGTAATCTGTGTCAAAATGGTAACTTGTTAAGGGCAGGAGTTTATAACTGAATGTCTGTAGTACATCTTTGTGCCAGTACTTGGCAACCAGCGCATGTATGGCTTGCTCGACTGTATTTTTATCGGCGGCGTTTTTTAAGGTGACAAGGATATTATTGCTTGAGTTGGAGTAGCCCCAATTATTAAAGAACCCGTCGTTTTGAGGGATTTGCCATAAAGTAGAAACAGAACTTTGCGAAAAATAGATTTCTGAACGGAAGTCTGAATTTTTGTTACGGTCATCTATGATACCCACAACTTTCACTGGAAATTTGCTGTCGACCAAGATCGTTTTGCCCAAGGGGTTATCGTTATTAAAATAAGTTTTGGCCATTGTTTTGGTCAACGCGACGGTATTGGGCTGATCCAGATCTTTTGGGGATCCCGCTAACCAGGGGAAATTTAAGGTGTTGAAATATTCCGATGAAACAAAAGCGGCTTTGCCCTCCGTTTTATACAACTGATCCGCTATCCGTAGCGTAAGGTCTTTATTATCCATATACAATGCTGTTCGTTCCACTTGTGGAATTTCACGTGAAATAGCATTGTACATGGCATAGGATCCGCCTTTGCTATGTTCGACCTGCTCTAGTTTCAGATCCTGTACGACTAGAAAGGTAAGTTCTTTATCGGTATGAAACTGATCAAAACTATATTGGAAGCTATTATAGCTATAGATAAATAAACTACATGCAATTGCCAGACCTAAACCAGCAATTGTTAAAAAGGTATAGTAGCTATGTTTCAATAGTTGTCGTAGCGCTGATCTGAAATATGTTTTAATCATAATTTTATTGTGTTGCGTTTACAATATCATTGTTTTTGTCGTATAGGAGATTATTCCTCCCGCAGACTGTCAACCGGATTTGCCACAGCCGCCTTGATGGCTTGCAAACTCACTGTCAGCAGTGCGATCAATACAGCGATTAGTCCTGCAACGGCAAACATCCACCATTGCATTTCAATGCGGTAAGCAAAATTTTCCAGCCATTTGTACATCGCCCACCAGGCTATCGGTGAAGAAATCACGATGGCGATCAGGACAAGTTTGATAAATTCTGCTGAAAGCATCCCTGTAATACCGGGAACAGAGGCGCCGATGACTTTACGTATACCTATTTCTTTCCGGCGCTGATTTGCCGTAAAAATAGCTAATCCAAATAAACCCAGACAGGCGACGAAAATCGTCAGTCCGGCGAATATGCTTAACAATTTTCCTGTTTTGACTTCGGCCTGATAGGTCTGGGCATAGCGATCATCGAGGAAAGAATAGTTGAATGGAATATCGGAAGGGAACGAGTCGTAGACAGCTTTCAATTTTTTAATCAGGGCCTCGGTATCTTTTGTCTGTGTTTTGACAATCAGGCTCCCAGCTTGATCGCTCAGTACCATCACCAGTGGTGAAATGGGTTCGTGCAGCGATTTAAAGTGGAAATCTTTGACGACACCCACGACACGATAGGTTTTGTTATCCTTATTGGTCAATGTATGGCCAAGGCTTTTCCCTTTCCAGCCCAGATCTTTTGCTGCGGTTTCATTCACGATAATGGATAAGGTATCGTTCCCAAAAGCTTTCGAAAAATTTCGCCCCTCGTTAAGCTGCATACCCATCGCAGCAATATATTCCTCATCTATGTCATAACGCAGTGTTTTCACCCATTTTTCTGTATTTCCGTCCGGATAGACAAAGAAGTTATTGTTGTTAGTTTCTCCAGCGGGCAGGTACGATGAGCGGGAGATATGTTTTACGCGGCTATCTTCGGATAGCAGCTTGACGTAAGTTTTTTCATTTTTGCCCAAGGGCCAGCTCTGGATCACAATGACATTCTCCTTTTCATAGCCTAATTTGATATTCCGCATATAATCGAGCTGTCGGATGACAACCACGGTGCAGAAAATGAGTCCCACGGAAATCATAAACTGAAAGACCACAAGGCTGCTCCTGAGATTGAATCGTTTTGTAGATCGCAACAAACGCCCTTTTAATACGGTCAAAGGATTGAAAGCAGCTAGATATAGAGCCGAATAAGTACTCGAAAATAGACCGACCAATAATCCGAATGCGAGCAGGAGGGGGATTATGCGGGCAAAATCGAGCTGTTGAATGGCAATGGACTTACCCGATAATTGATTAAATAGGGGAAGGGCCAATAAAACAATGCCGACTGCCAGAAACAGAGCTAGATAGGTCAGCAGGATGCCTTCGAAGAGGAACTGACGGATCAGGCTTTGCCTGTCGGCGCCGAGTACTTTCCGTACACCTACTTCCCGACTTCTCCGGAAACCACTGGCTGTAGATAAGTTCATAAAATTGATCGTCGCAATCAACAGCATAAACAATGCTATGGCACTAAAAATATAAATATATCGGATATCACCCGATGGACTGAGATCGTAGCCAAAATTGGAGTGCAGATGGATATCGGTCAGGGGCTGCAAATAGAGACCTATTGTATTGCCTGATTTTTTGTAATCCTCGTAACTCATTCCGAACCCGGCCATAAATTGAGCACCGACATGTTTGTCAAATAGGGTCGCTAAGTTTTTTTCCAGATTTTTTAATGAGGTATTTTCTGCAAGCAGTGCATAGGTATAATATTCGGATGTCATCCAGGAGTTTGAACGGGAGTCCTCCAGCGCCGTCATTGAGGTGAAAATATCAAAATGGAAGTGCGAGTTGCTGGGGATATCCTTCATTACTCCGGTAATTTTTAGCCTATTTTGGTCGCCTTTTATGGTGAGATCCCTACCTACGACATCTGTCGTTCCAAAATATTTGCGTGCCATGGATTCAGATATGACCGCAGTATAGGGCATCTTCACTGCTGTATTAGCATCACCTTTGATAAGGGGCAGGGTAAATATTTTAAAGAAAGAGGCATCAACATAGGCCATCTGTTCATCACGAAAAATCTTATCACCAACCAAAAATAAGGGAGCCCCACCTTGCCTCAAACGTGCTGTCTCCTGTACTTCGGTTAGTTCAGCTTTCATTGTGGCCGCCACCGGGGGCATGACATGAGCCTCATTCATCGTTCCCCCTTTTACCGTACCGCGGAAGACCACGCGTACAATTCGATCCGCATTTGTATTGAAACGGTCAAAACTGAACTCATCAGCAACATATAGGCTTATCAGCAAACAGATTGCAATACCCAAGGCTAACCCAGTGATATTGATGATCGAGGTGGAAGAATTTCTTCTTAGATTCCGCCACGCTATTTTTAGATTATTCTTTATCATAATCGGGCTGTGTTGGTTATTACTATTTATTTTATTCGTCCCTTAAACTATCCACCGGATTGCTAAGCGCTGCTTTAATGGCTTGATAACTTATGGTTGCCATGCTGATTAATATTGCCATTAATCCTGCAATAGCAAAATAATGCCATTGGATCTGGATACGGTAACTGTAATCCTGCAACCATTTGTCCATGGCCCACCAGGCTATTGGTGAAGCAATCAGAATAGCAATTATCACCAATTTAATAAAGTCCACGGACAGCAAAGAGGTTACTTGTGCAACACTTGCGCCGAGCACTTTGCGCACGGCAATTTCTTTCATCCGGGTTTCGGCCATATATGCGATCAATGCGAGAAGACCGAGACAGGAAATAAAGATAGTCAATCCTGCAAATACCATAGAAAGCGTGCCGATTGCTTTTGTTTCTTTAAATTTCTGCTCATAAGTTTTGTCGATAAACTGGTATTCAAAAGGATAGTCCGGATTGAATTTTTTAAAGATTGATTCAATTGTTTTCAAATTTTCTGCAATGCCGCGATTCGTATTCAAACGATAATGAATCGTGGTAAACCAGGCCTGTGGTCCTAAGATCACCATGGGTTTATTATCGCCAAATGGAGAGCCCATTATAAAATCTTTCACGACGCCGACAACGGTCCATTTTGTGCCGTCGCCATCTACAATGCTGTTTATCGGGTTTTTAAGATGCAGGCTTTTTACTGCAGATTCATTTAAAATCAAAGCGGTACTATCGGTCGCAAATTTATAGATATCGATATCGCGACCTTGGATGAGGGTAAGACCAAGGTTTTTTACAGCATCAGCATCGGTACTAAAACGGTTGTAAGAAATTCGTTTGTCTTCTTCGGTTGGTGTACCGGATGTGAATCCCCAACCATTGCTGTACATATCTGTAACAGGGGACATATTTTTTGATACGGAAACAACCGCATTGCTAGCTAACAATTCGTCCCGCAGGAGTTTATAATTCTTTTCCAAATCTCCTTTCAGACTGGAATATAATAAACCGTTTTCATTATAGCCGCGTTCGCGTTGTTTTGTGTATTGAATTTGTTTGGTAACCACTACCGTAGCGATAATTAATACAATGGCTAGACTAAATTGAATTACGACCAAGATCGAACGAACGCTAAGTCCTTTGGTTTTGGAAATAAATTTACCTTTTAATGTCTTGATAGGTTGAAAAGAGGAAAGGAAAAAAGCAGGATAAATGCCAGCAAGTATTCCAGTGAATACCGCAAATCCGATCAGAAATAACCAAGTCCACAAGTTTAATAAGGATAAGTTGAGCTGCTTTCCGACGAGTTCGTTAAAGAAAGGTAGCACAATAAAAACAAGTACTGTGGCTAGTATCATTCCGATCATACTAATCAGTATGCTTTCCGTCAGAAATTGAATTATTAATCCCATTTTATTTGCACCAACTACCTTTCGTACCCCTACTTCCTTCGCACGACGCTCTGAACGGGCAGTGCTTAAGTTCATAAAATTGATGCTGGCAACCAACAATATAAAAATACCGATCCATACAAAGAGCCTGACAATATCAATACGTCCGGAAGTGTAATTACCTCCTTTTCCGCTATTATAAAGGAAAGAGTCCTTGAAAGGAAATGCAAAAATCTCTCCGGTATACTTTGCAGATTGGTTACCTTCGGCTCTGTTGACTGTGTTAATATGATCTCTCGAATATGTCCTGATCTTGGTATTGAAATCTGAAAGCGAGCTTCCTTTTTTTAATAAAATATAAGTGCTTATCGAATTATTACCCCAATTGTCATCAACGTAACCGATTGTTTTTGCATATGCAAAAGGAAGCAGTATGTCAAACTTGAAACTTGAATTGCTGGGTAAATCTTTGAGTACCGCCTGTACGGTGACTTGGTTGACAGAATCGATTTTCACTGATTTTCCAATGGGTTCTTCATCTCCAAATAAAGCTTTAGCATAACTTTCTGTGAGAACAAGACCTTTAGGACCGTCAAACTGAATATTATTGGATCCTTTGACGAGGGGTAATGAAAACATGTTAAAAAATCCGGGATCGACAAACACTGTCTTCGCAATTATTTTTTTGTCACCGAATGTGGTCAAGAATTGATTGCCTTCATCATATCGTGTAAATGCTTCAATATCCGGGAAATCAGTTGCCATTGATGGGGCCATTATCTTGGGGGTGTATGCCCATGCTGATTTTTCACCCTGAAATTCATCCCGATTACTAATAATATAAAGACGGTCACTTTTCTCATGGAACCGGTCCATGCCTAACATGTTCTGTAACCACAGTGCGATAAGTAAAGCACCTGCCATACCAATAGCCAAACCGAGAATATTAATTGCCGAAAAAGCTTTGTTTTTTAACAAATTCCGCCACGCGATTTTGATGTATGTCTTGATCATGTTGTTTCTGCTAAATATAATAACGGATAATTATTCGTCCCTTAAACTATCCACCGGATTGCTAAGCGCTGCTTTAATGGCTTGATAACTTATGGTTGCCATGCTGATTAATATCGCCATTAATCCTGCAATAACAAAGTAATGCCATTGGATCTGGATACGGTAACTGTAATCCTGCAACCATTTGTCCATGGCCCACCAGGCTATTGGTGAAGCAATCAGAATAGCAATTATCACCAATTTAATAAAGTCCACGGACAGCAAAGAGGTTACTTGTGCAACACTTGCGCCGAGCACTTTGCGCACGGCAATTTCTTTCATCCGGGTTTCGGCCATATATGCGATCAATGCGAGAAGACCGAGACAGGAAATAAAGATGGTCAATCCTGAAAATAGCATTGAAATCGTCCCAATAGACTGCGTCTCCTTGAATTTAGCCTCAAAATTTTCGTCGATAAAATTATATTCAAATGGATATTCCGGATTGAATTTTTTAAAGATTGCTTCGATGGTTTTTAAATTTGCTGCAGTACTGTTGTTTGGATTTAAGCGATAGTGGATATTTGTAAAAAAAGATTTAGGCCCAAAGACGACCATTGGATAACTTGCTGCAAATGGAGATTCCGTAATAAAATCTTTGATTACCCCAACGACGACCCAATCCTGACCGTCACCGTTTATTGTTTGCCCAATGGGATGCTGTAAACGCATCTGTTTGACCGCTGTTTCGGTCAGTAGCATGGCATTGCTATCTGTTGGATATTTGTATATATCTATATCTCGTCCAGCAACAAGTTTAAATCCCAGCGTTTTCACGGCACCGGCATCGGTACTGAAACGGTCAAAGGAGATTTTTTTATCGCTCTCTGTGCTTCCTTGCCAAGAAAAGCCCCAGCCATTGCTATAACGATCCGTGACCGGGGACATGTTTTTGGACACTGATATCACCGCATTGCTGGCCAACAATTCATTTCGAAGGGTTTGGTAGATCTTTCCGTTGTTAAGTTTGCCTGTAAATCGGGTCGCAGCAAGCCCATTGTCATTATAACCGCGGTCCCGATCCTTGGTATGCTGGATCTGTTGCGAAACGATGACGGTCGCTATGACCAAGATAATTGCAAGGCTGAATTGGACGACAACTAGGATAGAGCGGACACTGAGCCCTTTGTTGTACGTATTCAATTTCCCTTTTAATGTTTTCAAGGGTTTAAAGGAGGAGAGAAAAAAAGCAGGGTAACTTCCCGCCAATACACCAGTTAAAAAGGTGAAGCCAATTAAGAACAGCCAGGTATTAACAGAAAGGATGGAGATCGTGAGGTTTTTTTCAACCAGATTATTAAAAGCCGGAAGAACCAACACGATAGCTACGAGCGCGAGTATCGTTGCGCCAATACTGATAAGGATACTCTCGACAATAAATTGTAGAATAAGACTTTTTCTTTGTGCACCGACTACTTTACGTACGCCGACCTCTTTGGCTCTTCTCTCGGAGCGGGCGGTACTGAGATTCATGAAATTGATACAGGCAACAAGTAAAATAAAAGCACCGATCCAGGTAAATAAATGAACTAACTGGATCCGCCCGGCAGTGTAAGCGCCATTTTCACTTTTGTTATAGAGGTAAGTGTCTTTGTATGGAAATGCAAAGATTTCGTTTGTCGACTTGATTTCGTTATCCCCTACATTGATATGGTTCTGGCTGAAAAGTCTAATTTTAGAATTTAAGTTTTCCAATGTTACCCCTTCCCGTAGCAGCACATAGGTATAGGTTGAATTGTTAGACCAATTTTCATCTACGAAGCCCATTTTCTTGGCCAGATCCCATGATAGCAAATAATCAAACTGTATACTGCTGTAGCTGGAAGGATCTTTTACGATCGCTTGGACGGTTACCAAATACTTTGATTCTATTTTGATCGTTTTTCCTATTGGATCATGGTCACCAAAAAGAGCCTTCGCATATTGCTCCGTAATGACAACTGAATTCGCATCTTTAAGTAGATTGGTTTTATTCCCTTTAAGTAATGGATAGCTGAACATATTGAAAAAGCCGGGATCGACAAAGCTGGCGCTTGAAACTAAATTTTTATCACCGTAGCTCGTTAGAAATTTATCATCTTGCTCGATACGCGTAAAACTTTCGATTTCAGGGAAATCACTTTTCAGTGTAGGTCCCATTATTTTAGGTGTATTTGTCCAGGCTTGTAATTCGCCTTGGTAAATGTCTCTATTACTAATAACATAAAGACGGTCACTTTTCTCATGGAACCGGTCCATGCCTAACATGTTCTGTAACCACAGTGCGATAAGTAAAGCACCTGCCATACCAATAGCCAATCCGAGAATATTAATTGCCGAAAAAGCTTTGTTTTTTAACAAATTTCGCCACGCGATTTTGATGTATGTCTTGATCATGTTGTTTATCTTGAAATAATTATTCGTCCCTTAATGTATTCACCGGATTGTGATTTGCCGCTCTAATGGCTTGTGAACTTACTGTCACGAAGGCGACAGCCAAGCCTGCTAATGCAAAAATCCACCACTGTATTTCTATTCGGTAAGAGAAATCCTGCAGCCATTTATTCATTGCCCACCATGCAATAGGTGAAGCAATTAGAATAGAAATAATAACAAGCTTGACAAAATCTTTGGATAGCATCGCCGTAATTCCGCTTACTGAGGCGCCCAGTACTTTACGAATACCAATTTCTTTGGTCCTCAGCTCGGCGATATATGATGCTAATCCAAATAAACCTAGACAGGAAATAAAGATCGCTAGCCCCGAAAAGATGAAAGCGAGCTGGGCTGTTTGTTGTTGGTCTTTGAATTTAGTGGCAAATTTTTGATCGACAAATTGATACTCGAAGGGATACGCGGGATTGAATTTTTTAATAATTTGTTCGATTTTTTTGAGCTGGTCGCTCATCGAAGCATTGGGATTTGTACGGATAACCAAATTGAATAGTGCTGTCTTATTCGCGTATATAAGCATGGGTTTTACCGGATTATAAGGAGAACCGCTGATATAGTCGTTTATTACGCCCACGATGGTATAGTTTCTGTCTCCCCATTTGAGATAACTTCCGATTGGATTTTCCAACTTCATTTCTTTGACGGCAGCTTCATTCAGCAGTGCAGCGGTACTATCTGCGGCTAATCTTGCATAATCGATATCACGTCCTGCTATGAGCTTTAATCCGAGTGTTTTGACAAAGTCACTTTCCGCTCTTCCCAGATCAAATCCCATTTTTTTCTCTTGCTCAGGAGTAGCTCCTGCCCAGGAAAAACCACCCCAGGAATTTCCAGAACTACCAGTGATGGACAATCCTATCCTTGTGACGGCTGTAGCCACTCCATTATTGATCAATTCTGATCTGATCGCCTCATAGTTTTTCCCTAAATCACCTTCCATTCCGATTTCGAGCAATTGAGCGGTATTATAACCAATATCTCGTTGTCCGGCATATTCAATTTGCCGCCTGACGACAATGGTAGCAATTATCAGGATAACAGCTATGCTAAATTGAAAAACAACCAATAATTCCCGAAAACTTAATGAAAACTTTTTTGACCGCGCAAATATTTTTAATGATTTAATGGGTTTGAAAGCGGACAGTACAAATGCCGGATATAATCCAGCCAATAGTCCCGTTATGAGGATAAAGCCTATCAACGACAGCCATATTGTTGTATCTGAGAACGAAAAGGTTAACGGTCTATCTAAAATCTTATTAAATAACGGGAGCGTAAGCTTAGTCAATACTATCGCGCTTAAGCCTGATATAAATGCTAGCAGGACTGATTCTGTAAGAAATTGGACAATTAAATTGAGACGTCTGGCTCCTACAACTTTACGTACAGCAACTTCCTTTGCTCTTTTTTGGCTGCGGGCGGTACTAAGATTAATAAAATTAATGCAGGCAATCAATAATATCAATAGACCAATTCCTGCAACCAGTTTAACCTGATCAATCTTTCCCCCAACTGGAATACCTTGTTCGAATCTGGAATACAGATGCATTTTGGACATTGGATACAGAAACAGCGATCCTTTTAGCTCCTTGTTGGATTTTTTTTCGATAATATTGATGAGCTTATTATTGAAAGCCTCAATATTGGTTCCCGATTTTAATTGCACGTAGGTTGAGAACGTAATTGTATTCCAATTTGGTGAATATTTACTAGCATCAGCTAACGGGATCAGATAATTAAAATCGAAATTGGTATTACTTGGCAAATCTTGCATAACAGCAGAAACTTTATAAGGTTCCTTATTGTCGAGCGTAATGGTTTTATCCAATGGATCGATATTACCAAATATACTTTTTGCTAAGCTTTCTGTTAAAATGATATTCTTTGTTTCTGCTAGGGCCTGATGATTATTTCCCCGTCGAAGTTTGAAATCAAATAGCTGTAGAAATGACGGGTCTACCTCGTTTCCTTTTGATTTGATTTTTTTATCATCAAACGACAGTAGTCTGTTTGTACTAAAATACATGCGAGCTGCGCGTTCTACTTCCGGATAATCTTCTAATAGGGCAGGAGCTGCTCGCCCTGAGGTGACGTCCATTAGACTTATTTTTCCCTCATCATTTTGATATTTATTCCAAAGTTTATACAGGCGATCTTTATTGCTGTAAAAATTATCGAATTGCAACTGGTTTTGCACCCATATGCCAATAATCAGTACAGCAGCCATACCAATGGAAAGCCCAATGATGTTGATTGCAGAGTAGCCTTTGCTTTTCCACAAGTTTCGCCATGCAATTTTAAGGTAATTCTTTATCATCGAATTGATATTTTGAATTTTTCATAATTTACTAGTCCATAATCCATTTATCCAAATGGATAGCTGTATTCATGGTCGTGCACAATAGAAAATGGTTAATTCAATTCGTTTGCCATAAATGTAATCTTTTGATTTTTAGGGTTTTGTTCTGGTTTTTTTTAAACCTAAATGTTCGGAAACGGACAGTTTGGTGTCCGTCCCCGAACAAATTGGTCTTATTCGCTTCTTAATGTTTTCACGGGGTTTGCCCAGGTTGCTTTGATCGCTTGATAACTAACTGTCAACAAGGTAATGACTAAGGCTGTTAAGCCTGTAACCGCAAATACAGTCCAGGTAATTGATATACGATAGACATAATTTTCAAGCCAAGATTCCATTAGGAGATAAGCCAAGGGGGCAGCAACAAGAAATCCGATCAATGTTAACCAGATGTATTCGGTACATAATAATCTCCATAAACCAAGTTCTGATGCGCCAAGAACCTTACGGATACCAATTTCTTTTTCACGTTGCTCGGTTAGAAATGCCACCAGAGCATATAGTCCAAGACAGGAGATCAGTATGGCGAGCCCCGTAAAAATACTGGTCAGGCTTTTGATCATTTCCATTTGCTCAAATTGCTTGGCGTATTCTTTATCTGTGAATGCATAATCAAAGATGAGATCTGGATCAAAGCGATTGAATTGTTGTGCGATTGCTTTCATTGTCTGACTGATATCTTGCTGTTCATTCAGTCTGAGTGTTATTTTATTTTTTGGTAGAAAATCAAGAAAATAGGCTGTTGGCGTAATCGACTTAAATGGGGATTCAGATAAGGTATTCTGTATAATACCGATAATTGTGTAGTTAATCCCTCTTTTAGACAATTGTTTGCTTGTCAGATCTGTAACCCCCATAAATTTGGCCGCAGCTTCATTGATGATTACTCCCGTGGAATCTGTCTTAAAATCCTTGGAGAAATTTCTTCCCTTCAAAAAATTCCATTGTACAGTGTTGGCAAAGTTTTCATCTACGGTGAAAATGCCCATAATGGATCCTTCCTTTGTTTCATTCCCCTGCCAGTTAAAACCACCGCCAGTTAAAGTGAGCTTATTGACAAAACTCGAAGTGAGTGATGCCTCCTGAATCAGGCCTTGATCAATCAATTCTTTTCTTAGGATCTCAAAGTTTTTGGAAATTAACTGACTGCTGCTAGTAACGTTTACTAAGTTTGAACTTTTATAACCGATCGGACGGTCTTTTGTATAGTGCAATTGTTTGATCACCAGATAGGTTGCAATCATCAAAAAGATGGAAATCGCAAATTGTACAACAACCATTCCCTTTCTGGCATTGAATCCTCTTTTGCCGATGTTCATCTTTCCTTTGAGCGCAAGGATCGGATTAAAAGAGGATAAGAATAGCGCAGGGTAAATTCCAGCCAGGATTCCAACAGAGAAAATCCCCAAAAAGGAGTATAGGTAGAATTGAATACTCGTAAATGGAATAGCTAATGTGGTTTTGGTAATGGCATTTATCCACGGAAGAAGCAAAGTGCTTATTATAAGCGCTATCAGAAAAGCACAGGATACGGACAGGATGGATTCAACTAAAAATCCGGTAATCAGTTGCCGGCGGTTGACACCGACCGATTTTAAAATACCAATTTCCTTTCCTCTTTTTAAACTTCGGGCCGTACTGAGGTTAATAAAATTGATACTGGCCAACAAAAGAATAAACACACTGATCCAGGCAAACATCCAGACATATTGAATCTGTCCACCGACATTTTTACCATTTTTGAAAGCGTCATAGAGATGCCATTTGGACATGGGGTGCAACAGAATCTCGGGGTTGATATCCGTCAGATTTGTTCTAAAGATGCTGGTTAGTTTATGCTCTATCCCGGGGATATTTTGCGGGTTTTCGATTCTACCAAAGGTACTAAAGAAGCAGTTTGACCATTTTTCGTCTATGCCTTCATTTTTACGGAGGTAATCTACAAACGGCAAAATATACTGCAACCCGTGAAAAGTGTTGTTTTCAGGTATATCTTTATAAACTCCTTGTATCGTATATTGTTCCTTCCCGTTGAGCTGAATAGTTTTCCCGATCACATCAGCCGATCCCATTAGAGCGTTGGCCAATGATTCGGAGATAATGATGCTGGAGGTTGCCGTTGGAGTGAGCGTATTTCCCAGTACAGATTCGAACGAAAATAGTTCTGAAAATTTGCCCATTGCATAAAAGCCAGAGGCATTCAGTTTCTTGTCACCGACTTTGATCGTATTACTTTCCATATCGGTGACCAATGCTAAATCTTGAATTTCATCGGTGAAATCTGATGCAATAACCTTAGCTAACGGAATGGGCGTGGAAGTCCCATCCGTAGATTTTTCACCATTGAAAGTTCCCGTCATCATCATCTGATAAATACTATCATGGTTTTCATAATGCTTGTTGAAGGAAAACTGTTTCGAGATCCACAGTGTACTTACCAATGCGACTGTAATTCCAAGGGATAATCCAAGAATATTGATTGCCGTATTTAGCGGGTTGCGTTTTAAATTTCTAAGTGCTGTTTTTAGGAATAATCGAATCATTTTATGGTGTTGTTTTTGGTCCTTAGATATAAGCTATTCATCGTGCAGACTTTTTACGGGATTGGCGTAAGCAGCTTTGATGGATTGGAAACTAACGGTAAATAATGCAATAGCAATTGTTATCCCACCTGCATATAAAAATATAGTCATGGGGAGTGTCGTTCTAAAGGCAAAGCCATTGAGCCAGTTTATGCTGAAATACAAAGCGATCGGTATAGCGATGACATTGGCCAGAATTACTAAGACTAAAAATTCCTTGTTTAATAGTTTTATAATGTTGAATACGGTGGCTCCAAGAACCTTTCTGATCCCAATCTCCTTGGTTTTGACCTGTGCGGTATAGGTACATAATCCCAGGAGTCCTAGACAGGAGATCAGGATAGCGATCAGTGCGAAGAAATTGAATAAGGTACCTTGTTTCTGTTCATTCGTATATTGCTTTTGGTAGCTTTCATCAAGGAAACTATAGTTCATAGGCATATCATCATAATAGTTTTTCCAGATCTGTTGCATTGAGTTCAAAGCAGATTTGGCTCCGGAAGCTGTTGTTTTGATATAAAGCTGCCAGCAATCTTTGGGGCTGTATTGGAATACCATCGGCTCAATTTTCTGCCTCGCGCTTGCATAATTAAAGTCCTTTACCACACCGATAATTGTTCCGGGAACAGTTCGAATCCGTAGGCGTGTGCCAATGGGATCTTTTAGTCCCATTTCGCGTACTGCCGTTTCATTGACAATAAAATGTGTTGAATCTGCTGTTGAGCCCGTAAAATTACGACCTTGCGTAAGTTTTATCTGAAAAAAGCTAAGCGCAGACTGGTCCGAATACGTAATATTGAACCAGAGATTTGATTTGCTGGGCTTTCCATCCCAATCGTTGTCTCCAGTGGAACCACCCCCATAGACCATATCCCGACCAAGACGGATAACGGCATCAATATCCTTGTTTTTTAGAAGTTCACTTTTGACTGCATCAAAATGCTTAGACATCTTTGGTGCCATGCCAATAGAAATAATATGATCTTTTTCATAGCCTAAATTTTGATGTTTTATGTAATCCAATTGGCGACCGATAACAATTGTCAGGGTAATCAGGATAATAGAGACTGTAAACTGCAAGACAACAAGTATTTTCCGTGCGCTGGAATTTTTTAGGGCAAACCGGCCTTTCAATACCTTAATCGGATCAAATTTCGATAAAAGGAGGGCGGGATATATACTGGTGAGCAGCAATGTACCGATGAGCATGGTCAATATGCTTGTCCATAGCGTAGGATTGCTGAGCTGCAGCGAAATATGTTTTCCGGAGAAGTTATTAAACAAAGGAAGGCAACTAAAAACGATTGCTAATGCCAGGGTTGAGGCAATGGTAAAGAGCAGAGTTGTTTCCAATATAAATTGGAAGAAAAGTTCCTTTTTTCCGGCCCCAATAATTTTACGAATACCCACTTCTTTGGCGCGGGACAAAGAACGTGCAGTAGAAAGATTGATATAATTGATGCTTGCGATGACAAGGATCATGATGGCTACGCCTATAAAAATTCGAACAGTGCCTATCCCCCCATCACTACCGTCCATCTGGTACAGATGTACCTTTGCCAGCGCTTGTGTAACATATGGTACAGGGGCATCTTCGGGTTTATTCCGTTCGTGTATGGATTGTAATTTTTGCGCGATAGTTGCCGGGTTGGCATCTGGTCTCAACTGTAGATAAGTTTCAAACGAAAAATTGGACCAATCTTCATCCATGGAGGATAGAAAGGTTTTATTGTCATAGGTCGTTTTGTTTTTGATATAAGCGTGTTCATTGAATCGCGATATCGGCAGTAAGACCTGAAATTGAAAGGTAGAGTTTTCCGGATAATCGGCAATGACGCCAGAGACAACACAGAGATCTTCAATGCCCAATATTACCGTTTTTCCAATAGGATTTTCATTGCCAAAATAGCGGTGTGCCGTACTTTGGGTGATCACAACGGAATTGTTATCGGGGAAAGGTCGCTTTGGGTCGCCTTGCATTAAAGAAAAGTCAAAAACACTAAAATAGCTAGGGTCCACAAATGCAAGGTTTTTTTCATTGAATCTTTTTTCCTTGTATTTTAGGGCGGCATCACCGATTTTAAATATGCGTACAGCATCTTGGACTTCAGGAATCTCCTTCTTAGCGGAGCTTCCGACAGGAGCAATGATGGACCCAGAGATCCGTTTTGATATGCCGGTGCCACCTTCTATACCAATTTTATAAATGGATCGATGATGTTTATGGAAGCGGTCATAGGATAGTTCATCCTGAATCCAAAGCAATAAGAATATCCCTACAACTAATCCTGCTGTTAACCCTAAAATATTAATGGCGCTATAAAACTTGTTGGAAAAAATACTACGCCATGCGGTTTTTATAAAGTTCTTTATCATTGTTTTAGGATTTAAGTCTTTAATTCATGTTATAAATGAAAGTTCAACTTGATCTATTCGTCTCTCAAACTATTTACCGGGTTAGCTTTTGCCGCCATAATACTTTTGGCTGATAGAACAACGCTTGCGAAAGCAATCAAGCTCAGGGCAGAAAAACCAAAAATCCACGGATTTATTGTAGTGCGATACACGAAATCATTTAACCAATTATGCATAAAATAATAAGCGATGGGAAAGGCAACCAAACAGGCTATGGCAACCAGGGAAAGTAAGTTTCGAAGCAGTAAAAATGTGATCTGGAAAACAGAAGCACCTAAAACTTTACGTATACCAATCTCTTTTGTCCTTTGATTGGCTGTAAATATCGCTAGCCCAAATAAACCTAATCCTGCAATAAATACAGAGAGCCCCACAGCCCAAGATAAGAGCTTAGAGAGCTGTTTCTCTTGTGTATAAAAGTTTTGAATAACCTCATTCAAAAAGCGCAGATCCAGTTCGTCATCAGGGAAAACCGATTTATAACTTAAAGTGATCTTGTCGATCGTGTTTTTCCAGTTTTCAGGATGCGATTGGTCCAATGCGATATGGAGTACATATCCTGTCTTGCTGCCTGTATACAGGACCGGTTTAACCCCTTGTCGTGCAGAAGCCAAATCAAAATCTTCCATTACACCAACGATGATATTTTGTCCATTTTCGAAGGTTTTACCGATGGCATCCTGAGGATTCTTGATATGCAGTAACTCCAGTCCTTTTCTATTGATCAACATTTCACTTGTTGAATCCCGTAAACGGACATTTCTTCCTGCTATAAGTGGAATTTTATAAACATCTAAATAGTTCTCATCACCCGACCGGCCATCGAAGGTCAGAGATTCCTTGTTTGGCGATTGATCGTAAGCGATTGCGGTAGTCATCCAGCCGTTCATTGCAGGGGCGATATTCCCAAAGCTGATGGCCTTGATATCTGTTAGCTTTTTGAGCTCGTTTTTAAGGATGACACCTTTCGCAGAGTTTTGGAAGGCCCCTGGGATGTAGATATTGACAATAGCGTCTTTCTGAAAGCCCATATCTTTATGGGTGACATAGTTGATTTGGCGAACGACAATAAGCACACAAATGAGAAAAGCCTGGGCCATGACAAACTGAAAGATGGTCAGTGCTTTGCGTAGCCACGAGCTGCGGGAAAGATTGGTGTTTTTTCCGAGCTGGTTTTTGAGCGCCAGTACCGGTGCATATCCTGTCAGTACCCAAGCAGGATAAAATCCGGCTAGTAAGGTCACTAAGATCAATTGCCCGAACAGAAAGAAAGCAATAACTGTTTTGTCCAAACGATCCAAATTTAAGTTTTTGGGAATAAATCCTTCAAAGACATGTAAGAATAAAGGAAGCAATAGTACAGCAAGTATCGTTGCGGATAAGGTAATAAGGAATGTTTCCAGTAGGAATTGTTTGATCAATGTCGCCTTAGAACTACCCAGTGTTTTGCGGATGCCAACTTCCTTGGCCCGTTCAATAGACTGAGCTGTGGATAGGTTGATGAAATTCACGGCTCCCAAAGCGAGGAGGAAAAAGGCCAGCAGGATCAGATTGCGAAGCGTTCCCGGGTGAGTAGCGTCATAGTTGAATCTCGTGTCAAAATGCACATCTGCCAACGCTTGTAACTCAAGTTTATCATTGATTTTCTCTCCTTCTTTATATTTATATTTTTGAAGGAGATTAGCGATATTGCGTTCCAGTAGATGAGGATTAGGTTGTGCTTTTGTTTTAATGAGCACCTGATGCGTGTCGGATATACTATTCCATGCGTCCCAGCTATACATATCTTTCAGACTATTGTTTTGTGGGATCGTTGATTCGGCAATGAAGCTGTCAAAATTAAAATCCGAATTATGTTGCGGGTTTTCAATTACTCCGGCCACTTGCAATGGAATACTATCTGCATAGATGACTGTCCTACCGATTACATCTGAGGGGGATTCCTTACCGTAAAATTTTTCTAAAGCCTTTTTTGTAAGCACAATATGGCCAGCTGTATTTAAGGTCTGGGCATTTCCAGCTAACCATTTATAGGGAAAAATATCGAAATATTGACTATTCGTAAAAACGATCTGTTGCTCTTTTGGAAAAACCTGAAATTTGTCTGTCGCCAAAGAAACCTTAAGTTTTTGTACATGGCTACGATAAATAGGAGCTACTGCTTCCAAGTTGGGCAACTCAGCCTGCATGGTGCGTACTAATGGTACATAAACACCGGCGTTTTTGAATTCACCGTTACTGACAACGCGATAGACCTGTTTTTGATTGGAAACATGTTTGTCAAAACTATAATCGTATTGGATCATTAAGAAAATAACAAGAGTCGCCGTAATACCAATCGCGAGACTCGTGATGTTGATGAACGTAATCAACTTATGTTTTTTTAAAAAACGGTAAGCTGTTTTAAGTGAATTTGCAATCATTGTTACTTCGTTTTTTGTTAATCAACGAGCAGCATCGCCGTTAGTTCAATCAGGAGGATTGGTATCAGGTGTTGCTATGCAAAGAGCTAGATCAATTCGTTTGCCATAAGTGTAATGTGTTGTATATGAGTGCTTAATTTTATTTTTAGCACATGTTGGGTTGTTCGAAAATGGACAGTATGTTGTTCGCTTCCGAACAAATAAGGAGTTGTTTTTATAGCTTTTGGCGCGATATGTTTTTTTTATATTGCGCCAAAACTCTGTTTTTTTATAGCTTTTGGCGTGATATGATTTTTTATATTGCGCCAAAACTCTTTTTTTTATTACTTTTAGCATAATATAACTTTGTTTTTATGGGTATTGTTATAGGTAGGTTAGAGGAAATTAGTCTGCTACGTAAAATAGAGCGGTCGGGTGATGCAGAGCTTGTCGCTGTTTATGGACGCCGTAGAGTAGGTAAGACTTATCTCATCAGGAACGGATTTAGTCGACCGTTGGATTTTGAATTTTCAGGTTCTCATCATGCTACATTGAAACAGCATTTGGAGAGTTTTAGCATGGCTCTTGGCAAAACCATGGGCAATATTCCATTGGCAGTGCCAAGTAACTGGCTACAGGCTTTGATATGCTCGAAAACTATTTTGCTCCATTAATAAAAAAGCGGCGATGTATTATTTTTTTTGATGAGTTTCCTTGGATAAATACCGCTAGGTCGGGCTTTATGCCTGCGTTTGAAAATTTTTGGAATAGGTGGGCTTCGCAACAAAAAAACTTGATTGTGGTGATCTGTGGTTCTGCTGCGGCTTGGATGATCAAGAATGTAGTCCGCAACCGGGGAGGCCTCCATAACCGGGTTAGTCGTCGGATACGTCTGCTTCCGTTCAATCTTTCTGAAACCGAAGCATTTCTAAAAAGCAGGAAAGTTACCCTTGATAGGTTTCAACTGATACAGCTCTATATGGCATTGGGTGGTATTCCGCAATATCTTAAAGAAATTGAACCGGGTGAAAGTACAGCACAGGTGATAGATCGTTTATGTTTTCAAAAGGATGGTTTACTACAGGAGGAGTTCAACAACTTGTATCGATCATTGTTTGATGATGCGGTAAACCACATGGACATCATTCGCGCATTGGCAAAAACGAGTGCGGGAATGACGCGTAAGGAAATTATCAAAACCTGTGACTTAACTTCTGGCGGACACGCGACCAAGTTGCTGGAAGAGCTTGCGGAATCAGGTTTTATTCAGCCTTACATCCCTTTCGGCAAGCAATCAAAAGATAGTATTTATAAGCTAACGGACGAGTATTCACTGTTTTACCTTCATTTTATAGCAAACAGTCGGACTAGAACTGCAGGCTCATGGATGAAGCTTGCTGACAAGTCCACTTGGAAAATTTGGAGCGGTTATGCTTTTGAATCGATTTGTTTTAAACATATAGATCAGTTGAAACAGGCGCTGGGAATTGAGGGAATATATACGGAGGTTTCTGCTTGGCGGCAGCGCGGATGGAAGGATGGTGTAGGTGTACAGATTGACTTACTGATTGATAGGCAGGATTTATGTATCAATGTGTGCGAAATGAAATTTTCTGTCAATCCATTTCAATTGACAAAATCTTATGCAGAACAGCTTGGTCAAAAACTTCGTATATTCAAGGAACAATCCAATACACGAAAGACGCTCTTTCTTACCATGGTGACGTCCTTTGGTGTTAGTAATTTGGAACAATATTCAGGCTTGGTACAGAAGTCGTTCACTATGGATGTCCTTTTTGATCGTTGATTATTTTGAACAAATCCACAATCCAATTGCGGATTTGTCCAAAATGGAAAGCTATTTCCGGATCATCATTCGTCCCTTAAACTATTTACCGGATTCAATAGTGCGGCTTTAAATGTCTGGAAGCCTATTGTGATAAATGCGACCAGCGCGACTGATATTATCGCAATCAGGTATGCCCACCAAGGCATCTCGATATGATATACAAAATCATTTAACCAATTACTGAAGAGGTAATAAGCAATCGGCCCAGCAATAAGAAAAGAAAGAATGATTAGTTTGATATAATTTGATGAAAGTAAGTGAATAATGCTCGGAACACTTGCGCCCAGCACTTTTCGGATACCGATCTCTTTGCTTCGTGCCTCGGTTGTATAGGCTGCTAAGCCCAACAAACCCAGGCAGGCTATAAAAAGGGTAAGAAATGAAAACAGGCTCATGACATTGGATGACCGAATTTCATTTTCATATTGATTTTGTACGTGCTGATCTAAAAACGAAAAATCGAATGCAGCTTCGGGTGCAATGGCCATATATATCTTCTTTACCTGTTCAATATATCCGCTAACATCTGTTGTTTTATAACGGATCAGTAAGTTTCGTGCCGATTCGGAAGGATCGTTCATGGTATAATAGCTGTAACCTCCAATTTCTGATTTAAGGTTTGAATAATTGAAATCCTGGACGACACCAGTGATGATAGAATTGGTCGGGCTCATCTCGGTAACAATATGTTTTCCGATGGCCTCCCCGGGAGATTTATACCCTAAAAATTTCAGTACCTTTTCGTTAATCAACACGTAGCACGTAGAGTCTGGACGTCCCCAGATATCGGGCAAATCCGTTCCCGCAAGTAATTTTAATCCAAGCGTATTTACGGTCTTTCCATAGGTAACGCAGCTTAACGTCGGCAGACCTTGCTTGTCCGTTGTTAATTTATAGGTTGTTTTTCCACTTTCGTTACTTCCTGGTATGGACTGTGCGAACGTGGTGGATAGCGTATTTGATAAGCTTTGGACCTGTTGGTTCAGTGTATTGAGTTTTTCATGGCTCCGGAAAGAACGGATAGGGATAGATACCACCTGTTCAGGTTGATAACCCAGATCTTTGTTCCGAATAAAATTCATCTGTGTAAGCATTACACTGATGCCTATGATCAGAATAATGGAAATGGTAAATTGACATATCACCAAAATTTGCCTGACCAAAACTGTTTTGCCCTGTTTGTTATAGCCCTTATTCATCAAGGCTATCGATTTGATTTTCGATAAAAATAAGGCTGGATAGCTGCCGGCAACAAGTGTGATAACAAACCAAGATATGGCTAATATTCCGAGCATATCCCAATTCAGAAGTTGTCGGATAGTAATGTTTGTGCTGCCTATGGTATTAAACAGCGGAATCAGAATAACAGACAGCAGCACGCCAAGGATCATAGCAAAAAGGCTAATCGTTGCGGTTTCAACAAAGAAACGGACAACGAGCTGGCTGCGGGTAGCACCAAGTACTTTGTTTACGCCTACTTCTTTCGCATTTTTTTGTGATTTAGCGGTAGCCAGGTTCATGTAATTGATGCAGGCAATCACGATAACAAGAAACGCAAGGATAGATAGCGTGCGAATGGTATCAATATTTCCCATACGCTTGGTGACGCCCTCCCCGAGATTTGATGAGTAAAGATGTACCTTTAATAATGGTTGTAGGAAAAATTCGGTAAAATATCGGTGATCTTTTTCGACATATTTGTCAATGAGTTTAGTTGCTTCTTGCGCAACAATTGCTGGATCAGCTCCTTTTTTTAGTAATATATAAGTCTCATAACTGGCATTACTCCAATAGACATTTTGCCCCATCCATGAATCCATAATATTCATGACCATATTACAGTCCAGGGTGCTGTTGGCAGGGAGATCCTTGAATACTCCGGTTACCTGTACAGTATCCCTTTGGTTAATGGAAATGAGTTTGCCGAGTGCTTCACTGTTTCCGAACAACTTCTCTTTTGTTGATTGGGAAAGCACAATACTCTTTTTGTTCAGGAACGCTGTATGTACACTACCTTCAATAAATTGGAAGTCAAAGATGGAGAATAGTGTGGAATCTGCAAGGTATAATTGTCTCTCATTAAAATTTTCCTCACCGGCGCGGATGGAAGCCGTTGCTCCAAAGCCATCTTTTACCAACCGTACCATATTATCGACCTGTGCAATATCTGATTTCAATGCGGGGCCCACTGCATTGGGCAGGTTGATCATCTTCTCCCGATTGTATTCCGCCGACAGCTGCATGTGCAACCGGTATATATTATTGGATTTTGTATACATGGTATCAAAACTCAGTTCCTGACGAATAAAGGCAAATAAAAGGAGTGAAACACAGATGCCAATAGCTAATCCGCTAATATTAAGGATGCTGAAAAATCGGTTGGCTCTGATACTCCGCCATGCAGTCTTTATGTAGTTCTTGATCATGATCGTATATGATTGTGTCGTGCTATATATAGTCGGTTTTTGTATTATGTTACTTACTCATCTCTCAGACTGTCTACTGGATTAGCTTTAGCGGCTTTAAATGTTTGATAGCTAACGGTGATCAGGGCAATGAATACAGCTGACAATCCGGCAAAAGCAAACATCCACCATTTTGGTTCAATATGGTACGCAAAATTGTCCAGCCATTTGTTCATCGCTATCCACGATAATGGTGTGGCGATACAGATTGCGATGACCAATAGTCGGATAAAATCGGAAGAAAGCAATAGCACTAAATTATAGATGGATGCACCGAGAACTTTCCGCACCCCGATTTCTTTGGTGCGCTGTTGCGCCGTATAAGTCACAAGTCCAAGTAAACCTAAGCAAGCAATGAAAAGGGCAAGGCTTGAAAATGCGGTAAAGAGTCTTCTAAAATTATAATCGGCTTCGTATTGACGGTTAAAATTATCGTCTAAGAAACTGTACAAAAAGGGACGATGGGGAGCGAGTTCAGCCCATAATTTACCGATTCTGTCGATCGTTTGCTGATTGACATGTTGTAAATTAACGGCTAGATAACGGCTGCTACCCGGTTCAAGACGCAAGGTTAGGGGTTCAATTTTACGATGTAAAGAAAGGTAGTTGAAATCTTTTACAACACCGATGACCGTACCTTCTTTGCCCCATTGTCTGAATTGTTTTCCAATAATGTCCTGTGGGTTTGAGTAGCCCCATAATTTGGCCGCAGATTCGTTGATAACGAGTGAATGAGCGGTATCTGCTGGGAAATCACGTGAATAGGCTCTTCCCGCAACCATCTTGATGCCCATATTGGGGATAAAGTCTATATCTACCTCATATAGGGATGGAGCGAAATCGGTCATTTTGCCATCTGTCGACATAATCTCTGTTCCGGCATTTGGAAAAAATGCTCCCGGTACGGTGCGTGAAGCTGTCACCGACTGCACATCTTTATCTTTTGCAAGTGTATTTTTGATTGCCTCTAAATTGTTGTTGACTTTTTCGTCAAAATTATAGTCGATGATTAGTCGTTGTGCTTTTTGAAATCCAAGATCCTGCTGTTGCAGTTGATTCAATTGCGAAAATACGATTACGGTACCAGCAATCAGTGCGATGGAGAGACAGAATTGGAAGACGACAAGACCCCGACGTAACAATGTCCCGCCCTTACTGCTGCTAAAAGCTCCTTTAAGGACTTTAATTGGTTGAAAGCTTGCCAGGATCAATGCTGGGTAACTTGCCGCTAAAAGTCCGGTGACAGTTGTTGCCAAAAGAAATATTGACCAAGTAGTACCGTTCATTAATGATGAATAAGTCAGGTGTTTTCCAGAAAATGCTTCTAAAAAAGGGAGAAAAGCAAGTACTAGAACAATTGCCAATAATCCACTGAAAAAGACAAGAGCCAGCGATTCGGACATAAATTGGAGAATCAGATTACTTTTATTAGCGCCGATTGCTTTTCGGACACCAACTTCCTTGGCACGTTCCATGGATCTGGAAGTAGCCAGATTCATAAAATTCACACAGGCAATCAGTAGAATAAACCCGCCGATGATCGTAAAAATATACAAATTTTGATAGCTGCCAGTTGCTCCGGGTTGACGATCTGCCGTAGAATGCATATAAGCCTGAAGCATGGGTTCGAGATGGAAATTGTATCTAGAATTGGCATTTTCTTGCACCGGGATATGTCGCTTGAGAAAATCAGGTATTTTTTGATTGAATTTTACGGGATCAAAGTCTTTTGAGGCGAGAAAATAGGTGTAAAAGTCCACATAGCCCCAGCCTTCTTTTTCAAAGACATCTGGTCTTGCTTTTCGGAATGTACTCATTGAGAGCAGAGCATCGAAGGTAAAGTGTGAGTTGGCCGGCACATCTGCCATCACAGCAGTTACGGTATATAAACCTGCATCTGCGCGGCCAGCAGCGAGCCCACCTTCAATGGTTTTGCCGATAGGGTTCTGGTCGCCGAAATATTTTTTAGCGGTGCTTTCTGTTAATACAACGGAATATGCATTTTTTAGTGCTGTATGTGGATTTCCGGCAAGGACTTTCCAGCTGAATACATCAAAGGCCGTTGAATCCATGAAAAATACATTTTCTTCCTGGAACCTATTTTCTCCTTTTTTGAGTAGGATGGACGTTTGCCCAGAGAATTGAACGATCTTGTCTATCTCTGGGAAGTCAGCTTTCAGCGCCTCACCAATTGGGGCATTCCCCCAGATCTGCTGCTGCGATGTGCTACCGACTTCTTTATAGTCATGTACGACACGATAAATGCGGTCTTTGTTGAGATGATATTTATCGTACGAGAGTTCATGCTGTACATAAATAACGATTAGTAAACAACAAGAAAGGCCAATGGCAAGGCCTATGATATTTATGGTGGCATACCCTCTATTCTTGAGAATATTGCGCCAGGCTATTTTAATATAATTTTGTATCATGGTTGCTGTTTTTTGATTTATTCAGTTATGTATGTTATTTGTTTTTAGTAAGATTGCCTTATGAGCTCTTCATTATTTTATGTAATCATCTTTTAAACTATGTATGAGGTTGGCCAATGCCTCTTGTTTGTTAATGAAATAATCGTGTAGAGATCGTAATGGGATCATTTCTGATACCCATCACTTTCTCTGATCACTATTGAGCTTCTTTTATTCATCTCTTAGACTATCTACTGGGTTGCTCAAAGCTGCGCGAACGGCCTGATAACTAACGGTGATAATTGCGATCAGCAAGGCCAAAATACTTCCCAGGACAAACGTTTGTACGTCCAGATCTGTTTTATAGGCAAAATTGCTCAACCATTGTTTCATCAGGTAAACTGCGATAGGGCATGCTATCAGAATGGCAATGGAAACGAGGATCACGAAATTTTTGCCCAGTAGTCTGACGACACCAAAGGTGCTTGCTCCGAGTACTTTGCGGATTCCGATTTCCTTTATGCGCATTTGTGCTTCGTGAGTTGCCAGTGCAAACAGACCCAAAGCGGATATAAAAATTGCGATGCCCGCAAAAATGTTGAATAACAGGCCAGTGCGGCGCTCCGATTTATACAAATTGTCAAACTGCTGATCGATGAATGTATAGTTAAATGGAGCATCGGAAGGATAACGGTTATAAATTTTTTCTAATGCCTTAATCGCCTCAGGAGCTTTTGTCGTACTTGTTTTGACATATAAAGTACCTGCTCCATAACGCGTCCAAAAGACCATCGGTCCTATTCTGTCTTTGATGGATTTGAAGTGAAAGTCTTTTACCACACCGATAATTTGTCCCGGAACATCATGAAAACTCATGTTGGATCCCACGTAAGGCGGTTTTAAGCCCATTTGTTTCGCTAAGGTCTCATTGATGACATATCCAGACGAATCAGCCGGCATACCGGTAAAGTTTTCTCCTTCCAGAAATTGAATACCCATCAATGGAATAAAATTCTTATCAATGGTTGCCTGAGCAACAATCAGTTTGTTGTCTTTGGACTTGCCTGGCCAGTCTATATCTCCGGTTGCATTTCCGAAATCCGTCATATTGTAAACGCCGGACAAGGAGACAGCCTGAATAGCGTTGTTGTTTTTGAGTTCGGTCCGTATCGCATCCATATGTTTATAGGCTTCTTCCGGAAGACCAAGAGTCATGACATGATCTCTGTCATAGCCGAGATTGATCTTTTGGATAAAAGCCAATTGGTTTCGGATCACCAGTGTGCATACAATCAGTGTCACGGAGAGTGTAAATTGGAAAACCACCAATATTTTACGCATCGTATTTGAAGAAACCCCTTTTACGGATTTTCCTTTTAACGAATGGATTGGATTAAATGATGAAAGTTGTATCGCAGGATATATGCTGGACAGACCCAGTGTCCCTATAATTGCGATTCCAATGTATAGCCATATTGCCGTATTACGGAAGGAAAAGCTGATTGATTTTTGTGCGATCTGATTATATCCTGTATGAAGGATGAATATAAGGATAAAAGCTATCAGCAGCGAGCAAAGGAATACAACGATTGTTTCCGTGATGAATTGTAAGAATAGGTGGAGACGGTTGGCACCGATTATTTTGCGGATACCAACATCTTTCGCCCGATCCAATGCTCTTGCGGTGCTCAGATTGACATAATTTACCGCACCGATGACCAGCAGCAATACGGCAATAATCCCAAAAATCTGCACCATGCGAAGCGTTGATTTATTACCGTCAGGAGCAATTAAATGCATGGTTTTTAACGGGTCTAAAACAAATACAGTCGAATTTTCGCCGTTACGGGCTTTGGTATAGGAGTCTGTGATAGATTTTCCGATAAGTGCTGCAGAAGTGTTGGGTTTGACTTTAACATAGGTTGAAAAACTGTAATTGCCCATGTCTTCATCTATTGTTTTCCATTTGCCATTACCGCCCCAGTTTGTAAATCGCTGTGCATGATAACCTAGCGGGATAACGACGTCGAACTGAATTGAGGAGTTTTGCGGGAGATCTTTTAGGATACCCGCCACGGTAAAGAGATCTTTCTGATAACGGAAAGTTTTTCCGATAGCCTGCTGGGTACTAAAAAGTTTTTCGGCTGTCGATGGGGTGATAAGCGCTTGTTTATAATTTGCCTGAAAACCTGAAAGGGAGCCCTCTTGCAACGGAAAATGAAACATGTTGAAAAAATTACTGTCAACATAGTAGATGTTCATATCCGTTACGGGACGTTTTAGCTTATCATTGACCAGCGTCGTATTGTGGTCCTGTGAAATACGCGTTGCATAGTCTACCTCGGGTATATTTTGTGCATAATTTCCGATCGGACCAGGAGAATTTTCCCATATAGAACCATTATGCTCGGGATCTAAATGAGAATTGACTTTGTAGATATGCTCATAGTCTGGATGGAATTTATCAAAACTTTGTTCATCCTGTACCCAGAGAATAATTAATATCGAGGCAGTAAGACTGACCGACAAACCTAATATATTGATAGCGGTATAGAATTTTCTTTTCCTTAATTCCCTGATTGCTGTTATTAAATAATTCTTTATCATAGAGATAGGTGTTTATTGTATTGATTACTATTGAGCTTCTTTACTGTTTTATTCATCCCTTAAACTATCCACCGGATTTGCGCGGGCAGCCCGCAATGATTGGAAACTTAATGTCATAAATGCGATCATTATCGTGAGTATTGCCGGGATAAAAAATAACCACCATTGTATTTCAATTTTAAATGGAATATCACGTAACCATTCGTTCATGGCCCACCAGGCAATTGGTGTTGATACCAATATTGAAATGATGATTAGTTTTATGTAATCTTTGGACAGTAAGCCAATAATACCGGTAACCGAACTTCCCAATACTTTCCGGATTCCAATTTCTTTTGTGCGTTGTACAGTTGTTATCGTGACTAGACCAACGAGGCCGAGGCAGCTCAGCAATAAGGTGATCGCTGTTGCCAGATTGATAATCTTAGACAATCGCATGTCAGTCTCGTAGAGAGACTTGATCTCCTGGTCGTAAAAACGGTAGCTGAATTTTGCATGTGGATAGATATTTTTCCATTCTTTTTCGAGGTTTGCCAATGCAGTTGGCCATTTTTTAGGATCATTGTCCAAGCGAACGTTAATATGTCCGAGTGGGCTTCTATTGGTCGAAACCTCCATCACAATGGGATTCAATTGTTGGTGGAGATCTTTGCTGTGAAAATTGGCTATGATACCAACAATTTTAACGTTTTTGTCGCGGGATACAACAGCCTGTCCAATTGCTTCGTCAGCGTTTTTAAATCCTAATTCTTTCATGGCTTTTTCATTAATTACAATACCCGAACTTGTGTCGGACATCGACAGTTTACGACCGGCGAGTAACCTAATATGGTAAAGGTCAATGTAATCCTGATCCACAAATTTGTATTGCATAAACTGATTTTTACTTTCCTCTTCGCCATATTTGCGAATCGGATTGCCCCAATAACTATTGTCCATAGGAAAATGCCCCAAGGAAACACGGCTGATTTCGGGATATTTAGCTAATGCCTGCTTGAAAACAAATGGATCTGTTGTCGCTTTATCAGCATTTCTATTTGGAATTGATATGGTGACAATTGCATCTTGATTAAAGCCTAAATCACTTTTGAGCATATGTTTGATCTGAATGCTGATCACGAAAGTGCCAATAAGGAAAATCTGTGCAATTACAAATTGAAAGATAATCAGACCTTTACGGAGAAATACCCCTTTGTTAGAATTGTTTGACAGTGATTTTATTTTCATCACGTCGATCAATCTTACTTTGTTGATCAGTATCGATGGATATATTCCTGCAAATAATGTAATTAAGACGAGCAATCCGATGATGAATAACAACAGATTGAACTGGTCGTTGTAGTTGTTGAGGTCTGGAGGAATAAAATCACTGAACAGCAATTCCATCATTTTTGTCAATGGCCAGGAAAGAAATAATGCGAATAGCGCGATCAAAAAAGTCTCTGTCAAAAAGCTTCTGGTCAGGTAAATTTCCCGTTCACCCAGTGTTTTTCGGATACCGATAGCGCGTGCGCGCATAGGTACCATCGCCGTACTTAGATTGATGTAATTGATAGCAGCTAATACAAGTAGGAAAGCAGCTATTCCGATAAGTCCATAAAGCACCTTGATATTGCTGTGATTTTGTATAATAGGGTTAAAATGAAGCTCAGATAATGCCGAAAAACGAACGGTTTGTTTGTAGTTCTCTTTTTTATATTCTTCGCCATTCATCTGCAATACTTTTTGATCGATGGTATGGGCTAGATTTTTGAGATGATCGGTGGATTTGACTTTGACGAATAGCTGATAATAGTTCATCAGCATCATCCAATTGTTTAGGTTCGGATCCTGATCAGGTATTTTGATAAACTCCTTACCAATAAAAGTACTTGGATAACTCAGGTCTTCTACAATACCAGATACAATAAACTGTGTCGTATCATAAGAAATGGTCTTGCCTATAATATCCTGATTTTGCAGCTTGGGAAAATAGGCTTTCGCGCGTGATGCGGTAAGAACGACCTCATTTTGGAGTTTGAAAAGCTGATGCGGACTTCCGGCAAGCCACTTATAGGGTACCATCTTAAAATAGTCGGCAGTTGTTGCAAAAATCTTTTCCTGTCCGGAAAATTCTGTGGGCGTTTCACTTTTGGAAGCCGGTGTTACGACTTCAAAATAACGATTATAATAAGGTACAACCAATTCGACATCTTGCGAGTTCTCTTTCAGGTAATAAGGAAGGGGAAATGGTACTGCGTCAAAATCCCCGCTTTCATTCTCCTGTTGTGTATGCGAATATACTTTGTAAATCTGCTCTTTGTCTGGATGTTGTTGGTCAAAACTAAATTCATAATTGACAATACGAAAAATAAACCAACAGGCGCTTATACCAATGGCAAGTCCCAATACATTCAGAAATGTAAAAAGACGATGTCGCCAGAGTTGTCTAAAAATCAATTTCACGTTACTCATTACAATTCAGTTTTTATTCTTTATAAAATGCTTTTTATTCATCCCTTAAACTATCCACCGGATTTGCGCGGGCAGCACTGATGGATTGATAGCTCATGGCTAAAAATGCTACGCCAATAGTTACTATCGCCGGAACAATAAACATCCACCAGCTGAGCTCTATTTTAAAAGCAAAGTCTGTTAACCATTTGTCAATCGCCAGCCAGGCAATCGGCGTGGCGATGAGTATTGAAATTATAATAAGTTTGATATAATCTTTGGATAACAATAACACGATCCCACTGATCGTGCTGCCCAGAATTTTCCGTATACCGATTTCTTTTGTCCGCTGATGCGTAGTAAGTGTCACTAATCCGATCAATCCCAGGCAACTTAGCAAAATGGTAATGGATGTTGACAAATTGATTATTTTATAAAAGCGATAATCTTTCTCATACAGCTCTTTGATCCGCTGATCATAAAATTGGTAGGCAAATGGTGCATTTGGATATACGTTTTCCCATTCGGTCTTTATAGATGCAATCGCCTGGTGCCATTTTTTAGGGTCTCCATTTAATTTGATATTAATATTCTGCAGCGTGCCCTTGTTGGTTGAGATTTGCATAGCAAGGGGTTCTAATGGAGCATGGAGATTAAAGTTGTGGAAATCGGCCAGTATGCCTACAATTGTGGTTGGACGATCGTTTACAGTTACGGTTTTTCCGAGTGCTTCCACCGGAGTTTTAAATCCAAACTTACTAATGGCCTTTTGATTGATCAGTATTCCTGATGTTGTATCCGAAAGTTTGAGGGGCCGCCCGGCCAGTAATTTCATTTGGAATACATCCAGGTAATTTTCTTCAATATATTTAAAAGGCATATTGACCAAGATCTGACCGGTATCGCTCTGCATCATGATATTATTTCCCCATTGGTCGTTATTCATTGGGAGGTGTCCTAGCGAAACCTGGTCGATTTCAGGATATTTTTGGAGAAGTTCTTTCAAAAGAAACGGACTTTTGCCTGAATCTTCTGCTTTTTTATAGGGCAGTTTGAGGGTAATAACAGCATCATCCTGAAAGCCAACATCACTGTGTAAAGCATGCTGTAACTGTAAACCCATGATCACTGTCAGTACGACAAAAGCCTGGGCGATCACAAATTGAAATACAATGAGAATCTTGCGGAGTGAAATACCACCAAAGGAAATTTTATCGGTTGCATGTATTTTTATGGCTTCGACGACATGGACTTTATTAATAAGGTAGGCTGGATACAGACTGGAAATCAACGTAAGTAGGATAATAAGACCCAATAGAAAGATAAAAACAGATAAACCATCTGAATAGGCATTTATATTTTGCGGGAGATATGAACTAAAGGTAAGTTCAAATATCTTGACCAATGGCCAGGAGAATAATAGCCCAAATAGACAGGTAAAAAATGTTTCTTTGATAAAAGACAATGTCAGGTGCCGGGGTTGCTCACCCAATGTTTTTCGGATGCCGATTTCCCTGGCCCTGGCGGGAACACGGGCTGTCGTCAAGTTGATGTAATTAATGCTGGCCAGTATGAGCAAAAATGCCGCAATGCCAATAAGTCCATACATGACCTGCTTGTCACTGCTGTTTAAGACGAATTTATTGAAATGTAATTCAGTAAGCGGAGCTAATTCGTAACCAGCCGTTATATTGTACTGTTTGAATTTTTCTCCGACCATCTCATTGAACTTTTTGGTTGCAGCGCCAATTACTTGCGCGGGACTTCCGGTTTCAGTTAATTTAACATAAACATGGAAATTTGAACTTGAATTTTCCCAATTCTCTGCTTCCTGAGGATTGGGGTTTACACGGATAAATTCTTTGGAGATAAAACTGCTCGGGTAGTCTAAGTCGGCGACAACTCCGGTCACGGTAAGGAGCTGATCATCGTATTGCATTGTCTTGCCGAGAAGGGATTTTAAGTCTGCATCGGGGAAATATTGTTTTGCACGTGAGGCCGTCAGGATGATCTCATTGTTGTTTTTGAGTGCGGTATTCGGATTACCAACAATCCATTTGTAGGGAACAAGTTTAAAATAGTCCGCAGTAGCAGAAATAATTTGGTCCTGCTCATTGAACTCCAAGGTTTCATTGTTGGAACGCTTAACCTTGATGCTTTCAAATGATCGATTAGCGATCGGTGCAACCAATTCCAATCCGGTCAGATCTTTCTTTAAATTATTCCCGAGGTAAGTACCAAGCGGGTAGGGAGTCCCATCAAAACGATGGATATTTTCACCTTCCTTAAAGGCGGAGTAAAGCTTATAAATCCGTTCCTTGCCGGGATGATTCTGGTTAAAACTGAATTCGTAGTTGACAATCCGAAATACAATCCAGCTTGCGCTGATCCCGATCGCTAGACCGATGATATTAAGGAAGGTAAACAGACGGTTACGTCCCCATTGTCTTAAAATTAATTTTAAACCTTTCATCGTTTTATAACTTTAAACTCGTTTAATAGCTCTTGATCCTGTATTGGTAAGCGCTTTAGATCTTTAAGAACATTTCTTGTCCTTAAAATGGGCCGCTAGCTTTACTAGGATCCTAATGATGTTGTTTCCATAATAACCTGTCCATCCAGCATGCGAATGACACGATCCGAAAATTTGGCGTCGTGCTCACTGTGGGTTACCATCACGATGGTTGTGCCGGCTTCGTTCAATTCGGTTAAGAGTTGCATCACTTCATTACCGTTGTTGGAATCCAGGTTACCGGTAGGCTCATCGGCAAGAATTAATTTCGGATTATTGACGACCGCACGGGCAACGGCCACACGCTGTTGCTGTCCCCCGGAAAGCTGTTGCGGAAAGTGGTTGCGACGGTGCATGATCTGTACTTTTTCCAATACTTCCTCGACACGTTTCTTGCGTTCTGCAGCAGGTACGTTGGTATAGACAAGAGGAAGTTCCACGTTTTCAAATACGGTCAGCTCATCAATCAGATTAAAACTCTGAAATACAAAACCAATATTGTGCTTACGCAAATCCGAACGGCCACGTTCCTTGAATTTGGCGACTTCAATCTCGTTGAACAGGTAGCTTCCCTCATCCAAATCATCCAATAAACCGATAATATTCAGCAGGGTGGATTTGCCGCAACCAGATGGACCCATCACGGCGACAAATTCACCCTCTTTTACGTGAATGTTCAAATTGTTCAATGCCACAGTCTCCACTTCTTCCGTGCGGTAATACTTTTGAAGATTGGTTATTTTAATCATATTTTTTGCGCTCATGGTTTTATGTTTTGGGCCCTTGGCAGCAGCTTTGGGCAGTTATTATTCTGTTTAAAAATATTCTTTATAGTGTTTATTTTTCTGTTTATTCGTCTCGGAGTGTTTTGGTAGGATTGGCAATTGCAGCTTTAAAGGCCTGTGAACTGATCGTCAATAAAGCTATTACTATTGCGGCTAGTCCGCTCAATACAAAAACTGTCCAGGAAATTGTGATATGATGCGCGTAGTCTGCCAGCCATTTGTGCATAAAAATCCAGGCAATTGGAAAAGCAATAATACAGGAGATACCAATAAGGATAATAAATTCGCGATTGAGCATCTGGATAAGCCCAGAAACTGACGCTCCTAGTACTTTGCGGATACTGATTTCCTTGGCACGTTGTTCTGTAGCAAAGGCGGCTAAACCAAATAGGCCTAAGCATGAAATAATAATAGATATGATGGCAAATACGCTGGATAGCTGTTGTATAAAAAGTTCAGCCTGAAATTTGCTATTGAAGGTTTCATCCAAAAATTTGTAATCGAAAGGAAATCCGGGATTATTTTTTACAATAATCTTTTCAATTTGCTGAATAGCTTGTGGTAGATCAATTCCGGCTTTTGTCCGGATATTTAATAGGCCGCTCTCTCTGACCAAGGGAATAAATAACATCGGATCTGGATCGGCATATACGTTGTTATAAACAAAGTTTTTGACGACTCCGGCAATAGTATAATTTTCTTCGCCGTAATTAAGGATACTACCCACAACATGACCATCTTTGCGGATTAATTTAGCCAGAGTTTCATTAATAAGAACCGAAGTGCTGTCTCCTAGTAAGTTGGCATGGAAGTTTCTTCCATCAAACATTTTAAGATCTAATGCTGGTACTAATCCTTCATCTGCGCGCAACATGCCGATCAGAATACTCTTGTTGGGATCTTTTCCTTCCCAATTGAAACCAGAGGTATTATTGTAAATGTTGAGAATACTCACATCACTGACACCGACCTGCTCCACTAGTCCAGTTGCGATGAGTTGGTTTTTGATTAGGGGAAGATGTTTGGCCATGTCCCCTTGCAATGCGGTGGTCAGTACCTGGCTCTTGTCAAAACCCAGGTCTTTATTTTTGTTGTGTTGTATTTGCTGATAAATGATGATTGTACAAATGATCAGTACAACTGATGCGGTATACTGTAGCACAACTAATCCCTTGCGGATAAGACTTCCGGTCCCGGCTTTCTGCTTTGCTCCTTTGATCGTAGACAGTGGTTTAAAAGCGGACAGAAAGAATGCGGGATAGCTTCCTGCAAATAGTCCGCATATTAAAGTAATTGTGATAACAAAGGCAAGATGCATCGGTTTTAATAAATCGACCTGAAGGTCTTGGCCAATCATGGTATTAAATGGCCGAATACAGATATAGACCAATAAAATAGCGACTAAAGAGGAGATAGAGGCTAGGACCAATGATTCTGCGAGAAATTGACCGATCAACGATTGACGGCTTGCGCCAACAACTTTGCGCATACCGACTTCTTTTGCTCTTTTTTCGGATCTGGCAGTAGCGAGATTCATAAAATTGATACAGGCAATCAGCAAAACGATCCACGCAATAATGGTGAATAGACGAATATTTTTTAAGCTTCCTTCTATTTCATTTCCACTGTTATCAAAACGGTTATGCGTAATCCATCTTTCCATTGGATAGAGGAAGTTTTGTGAAAAAGTAACCTCACCATTGGTTCTGTTTTTGACATAGTTCATTAGCTGTTTGTTGATTTGATCAACATTTGCATTGTCTTCAACCTGAATTAAAGTCTGGATGCCATTATTGTCCCATCTGGTCAGCCAGTCTTGGGTAGATTCAAATTTTTTGAATGGAATTAACCATTGAAATTCGTAACTACTATTTTTAGGAAGGTCCTTTGTAATGGCTGAAACGATGTAAAGGTCTTTGTTATTAGTCTTCACTGTTTTGCCTAGAGCAGGTTGATTACCAAATAATTTTTTCGCACCAGATTCCGATAAAATGATGTTATCTACTTTGTCAAATGCGGTCTTACGATCTCCCTCCGTAAATTCAAGGGAAAGCAAGTCCGCAACGGAGGCGTCAGCATATAACCCATTTTGAAATAAATTGTTGTCACCAACAGAGAATAACATTGGGTTAATCCATGTCATACGTACAGCATGTTTAATGCCCGGAATCTCTTTCGCTATATTTTGCGCCAGGGGACCTGGGGTTGATTCGAACACAAAGGTTGCGCCATCATAGGTCTGTTTTGACTTAACGATGTAAATATCCTTTTTATTGGGAAAGTTATCATTATAACTCAACTGATTTTCTACCCATAAAAATATCAGTGCTGCCGCAGCAATGCCAATTGCTAACCCAAAAATGTTGAGGAAGCTATAACCTTTGGTTTTCCAAAGGTTACGAAAGGCTGTTTTTATAAAGTTCTTTATCATCGTGTATCTTGTATTATTATTTGTTCTGTATTTTTCTATTCGTCCCTTAAAATCTTCGTTGGATTAATCATTGCCGCTTTCAGAGAAACAGATCCTGCTGTAAGGACCACCAATAAAATAGTTATTAGGCTTGCCAGTAAAAAAATCCAAGGATCTATTGAAGTGCGGTAAACAAAATTGTTAAGCCAGTTTGAAATGATAAGCCAAGAAATGGGAAATGCAATAAGAAAAGAAAGTATCACGGGAACCATATAATCTTTCCCGATCATCATGACAATATCTTGTTTGGATGCGCCTAAGGTTTTGCGGATTCCGATCTCTTTAAGTTTAGCTTCTGTACTGAACAATACAAGTCCCGACAGACCAATACATGAAAGCAAGATCGTAATGGCGGCAAATAGTTGGACAAGTTTTCCATGAACAACATCTTTTTTATACATTTTATCAAAAGATTCGTCCATAAAAGAATAATTGAATGCTGATTCGGGATTATATTTATTCCATAATTTTTGGACAGCACTCAACGCTTGCTTTTCCTGCCCTGGGCTTGTTTTGACATACATGCCACCGAGTGCATAACCCATGCCTGAAAAAAATATGCAAGGTTTTATCGCTGTTTTAAGATCATTAAAATTAAAATCTTTCATAATCCCCACAATAGTCAATTGTTTACCCTGAAAAGTGATGGTTTGTCCAATTGGATTCTTTAGCCCCATTTGTTTAACTGCTGTTTCATTGAGCAAAGCATGGCTGCTATCTGAAGGGTTGTTTTTAAAACCATTTCCTTCGGTTAATTTGATATCCAATACGGACGTGAAATTTGGAGCTATTGCAACTCGGCTGATAAAGAAATTGGATTGCATGCGGTTTTTTCCATTCCAATCGATATCTGCGGTTTCGGAGCCGATGTTACTGATATCATTGCTGGCGGCCGTTACACCTAAAATACCCTGCTGTTTCTGTAATTCGTTACGGACAGCCTCATAATGCGTTAAAAAGTTTTTCTGCTCAAATAGAAAGACATTCTCTTTGTCGTAGCCCAAGTCTTTGTTGCGCATGTAGCGGAGCTGTTTTTCGAAAATAAAAGTGGTAACAATAAGTATCACGGTGCAACAGAACTGTAAGACAACAAGACCTTTTCGAAGATTATTTTTATTACCAAATAAGGTATTGTTATTTTTTAATTGACTCAAAAGCTTGCTGCTTGAAAAAAGTACTGCAGGATAGATTCCTGCGATAAATACAGTTGCTATAAAAGTGAGCAGAAAGATATACCATAATTCAGAAGAAAGTAGGCTGAATTGAATATTCTTTTCCGCTATTGTATTAAAAAACGGAATACTTAAATAAGCAATCGCTGTTGCTATAAATAGTGAAATCAGAAATAATACAGCAGATTCAATAAGGTATTGAAGAAATAAGTGACTTCTATTGGCTCCGATAATTTTGCGTATACTGATTTCTTTTGTTCTTTTTGTAGCTCTAGCAGTAACTAAATTGACGTAATTAATACAGGCAACCAGCAGTATGACAAAGGCAATGATCGCGAATATATAAATGGACTGTATACCGTTATTGTCACCCTTAGGGGTGTATAAATTTAACTGTGTTATTTTTTGTAGAAAGAAAGCGAATTTGCTATACAATGGGTTTCCTTGGAAATTGCTTTTTTGAATCGCAGTCAATTGCTCCGCTACTTGGGCTGATTTGCTATCTTGTTTTAACAGAAAATAGATATAATATTGAAAATTGCCCCATTTCTCATCCAATGGTTCTTTGGAAAGGCTGTTCAATAATTCAAAAGGCAATAGGTAATCAGCCTTAAGTGAACTATTACTTGGAAAGTTGTTGACTACAGCAGTGATTAAAAAGGGTTGTTTACCTGTTTTCAGAATAGGATCGACTTCTAAATAGAGCGTCTTTCCCAAAGGGTTTTCATTTTTAAAGTATTTATTAGCAATCTTCTCTGTAATGACTATGGACTGTTTCCCTTGGAATAACTTATTAGGCTCCAATAACTTTATAGAACTATCAAATACCTTGTTAAAGGTACTATCAACATACACACCATATTCCGAGGTCATGAGTTCGTTTTTATTGAACTGTATATTCCGCCCCCCGCTTATACGACAGATTTCTTCAATAGCTGGAATTTTTGATTTGCCATAAATAGCAATCGGTGGTGGGCCAGCATGCACAAATTGATCATTTTCTTTATCAAAGTTTGCGGAAAGTTCATACACCCGGTTCGAATTATTAAAGACCTTGTTAAAGGATAGCTCATCCGTAATCCAAAGAGCAATGATAATAACGACCGCCAGACTAATACTTAGTCCAGCAATATTCAAAAGTGTAAACTTTTTGTTTGTCAGTAAGGAACGAATTCCAGTTTTGATCGCGTTCTTTATCATTTTTCTTATGCTCTTATAATAGCGGATATTGAAAGGATTGGATGTCTCTTCTATTTCAATTTTTTAATGACCGCTATGCGATTTTATCTTTTAATACTTAATTCCTGTACCTTGTCATATGTTTCGTAACTTGATACGACAACCTTGTCTCCAGGTTGCAATCCTTTGATCACCTCATAATATTCGGGGTTCTGTCTGCCCAGTTGGATATCCACACGATAGGCTGTGCCTCCATTTTTATCCAATTTGAAGATCCAGTTGCCACCAGTCTGCTGATAGAAACCACCTTTAGCTAATAATAATGCTTTCGTTTCATCACTTAAGGCAAGACGGATCTGTAAAGTCTGTCCGCGGCGGATTCCTTTGGGAACGTCATTGATAAATTCCATATCGACTTGAAAACGACCGTTGGTTACCTGTGTATAAACCTTTTTAATGCGAAGTTTGTAGGTCTTGTCACCAATGGAAAACTCACCTTGGAGATCTGGAAAAATGCGGTTAATATAATGCTCGTCGATATCAGCACGCACTTTAAATCCGGTCAAAACGTCAATTTGACCTAAACGCTCGCCAGCATTTTTATTCTGTCCGATTTCGGCATCAAAAGCTGTTAACTGGCCATCGACAGGTGCCCGGACAATCAGGTCACCAATTTTTCTTTTCATTAACTCCAATGCACTCTGTGTACGCTGGTAAGTCTGCTTGTCCTGATTGGTCTTTTGCGCATTGGAGATCTCGTCCTGTTTTAGGATCTGTTTGGTCAAGTGGACACGTTCCTTTTGATAATTATATTCGTTCTTCGATTTCTCGAATTCTTGTGTACCTATCGCTTTTTCTGCAAGTAATTTTTTATTCAGATTATAGACACGTTCAGCTTCTCGATAGGCCTGTTCTACATCAGCCATTTGATTACGATTGTTGATAGATGCCTGTTGCGCATTCGTCTGGGCGATTTGCGACTGTGTTAATAGGTTCAATACCTGAGTTTCCTGTTGAACTAATGTGAGCTCTTGATCTGTATTGGATAGACGCATAATCGGGTCGCCTTTTTTTAAGACAGTACCATCCTCAACAAATTTTTCCTCCACACGACCACCCACAGAAGCATCAAGATAGATGCTGCTGATCGGAAGCACTGTACCATTTATCGGAATGAATTCCTGAAAATTACCATTTTTTATTTCGACTATGGAGATGCGGTCAGCCTCTACATTGAGTTTGCTTTTGCCCGAGGTAAAATAAAAGCTAGCACCGATTAATCCAACGATGCCAGCAACCCCTACGATGGTCAGTATACGTTTGCTATTCCACTTCTTCTTTTCTAAAGGTCTGTCCATAATTTAATATCAATTTGCTATCTAACTATGAAAGCTGTGCCAATAATTTAACATGTTGATTTGTAGTTGTTTATTTTGTTTTCCTTTGCGTTCGGTGTTCGATAGCGGACACTTCTTGTACGGAGACGTACAGCCTACAGTTTTTTACCGCTAGGATAGCGGGATTTTATTAATATAACCACAGGTTGTGGCAGGACTCGTTTTGTTTTAATAATTTTGTGGATCAACATTGATAGATGATTCCGTTACGGAATTTTTAACTTTCCCGATCTTATCAATTTTGATTAATTTTATCCGTTTAAATAATTAATTATTGACTGTTATGATAAAGAAAGTTTGTTTTTTTCTCCTGTTACTATGTAGTGCTTTTTTGGCTAGCGCTCAATTTAACAATACAAATTCTTTGCTATGGGAAATAAAGAAAAAAGGAAATGTTGAAAGTTCATATTTTGTATTAGTCACGGGAGATCTGTGTGATATTCCACAGTCTTTACTGGATAGGATTCTTGGTTTACGTTCCAATATCCACACATATTATATGGAGTCAGCATTATCAAATAAGAAATCTGATAGTCGAAGTGCCGAAGTAATGTTTTTGAAAAAAAAAGAGCCATCTATTCGCGGATTTTTAACGGATAAGGAATATGATCGACTGCGGGAGCGAATGCGTGAAATGAATATCGATGAAAAAACGTTGAATAAGATGACTCCTGTATTTATCGAAAACTTATTGAAAAGAAAAGCCGCGGGCGACTGTAATAAAACTAATGTAATTGCAAAAACCTTTAGTGAATATGCGGGGCAGTATGGGATTGAGGTGAAAGAATTAGTCGATTTTGAACATTCGGTTGCCAACTTGTTGGGTGTTCCCAATGAATGGAGAGTTGAGCGGATTAAATATTTTCTCGCTAATGAAACAGAATTGAAGGCAGATTTAGCGAAGAAGGCTGCCTGTTATGAACAAGAGGATACAAAAGGTATTATTGACCTTTATTCATTGAGCAGGTTTTTGCGGCCCAGTGAAACAGATATGCTTCGGGCAAAGGAACTATGTCCCCTAATTGAAGCGGCGGATAAAGGCGGTGTACTATTTACTGTTGATCTAATAAACTTGGCAGACAATAAGAATAATTTATTTGATCTGTTGCAACAGCGTGGATATCAGATGTCTCCGATTAATTGATCCCCGATCGTGCTACTGACAGTTATTCTTATTGGGTGTTGCCTGATATTGTCCAACTACGCACACCGACTGTTCATTAATGAACATTTTTGAAAATACTTTTTTTGTATCTATTTGATATATAGTCTTTTCGTTATTTGGCATGGCGATGGTCTGTTTGGAAACAAAAAGTGGATATGAAGAGAATCTATATATATAGTACATTGTGTTTTTTGCTGGCTTACGCGAAAGTGGACGCACAACAAAGTGAGCAGGGAATAGAAGAGAAGGCTGTCTTCAACAAGGAATCAACCGTCAATAGTGAAAATCAGCGACCAAAACGTAGTTTGACTGAATGTATCCAATTGGCAATAAAAGCCAATCCAACTTTATTACAGAATGAATTAGCTGTTAAACGTGCAGAAGTGAATCTTTCGCAAGCAAAGGCTAACCGATTACCTGATTTAAATGGACGATTAGGTCACAGTCTTACCTCCGGACGTTCGGTTGATAACTCCACAAATCAGTACATTACCAGAAATAACTCTTCTGGAAATTTCTCGTTAGATGCTAGCGTGCCGGTATTTAACGGATTTCGGATTTTAAATGATATCCGGATGCGAGCTGATGCGAAGACGGCCGGAAAACTTGAATTTGATTCTCAGGTTAATGCTTTGAAACTTGATGTTATTACAGCTTACATCCAGGTACTGACCGCACAAGATGTTTTGAAGCAATCTGAATTGCAGACTGAGGTGACACGTGAACAGGTGCGTCGTGCCGAAGCAATGCAAAGGGAAGGCGCCATTAATCCCGGAGATTATTATGATCTGAAGGGGCAACTTGCCAATGATATCAATTCTATCGAAAACAATAAACAGATTCTTTATATGAATCGTGTTAAAATGGCGGGTTTTTTAAATATTGACGAAGCACAGCTGGGCGATCTACAAGCATTGGAATTGACAACTGACGCGCAAAAAGTAGATGCTACAACACTTTATAAATTGGCTACGGAAAACCTGCCGGATATTCCGGCACTGGATTGGAAAATTAAAGCAGCCGAAAAGAATATCAAAATAGCACAATCATCCTATTGGCCTTCTTTATCATTAAGTGGTGGATTGAATTCGAATTATTCCAAAAATGGAATGGAAGGGGATTATTGGTACCAAATGAAAAACAACGTTGGGAAATACGTTTCGCTCAATCTTTCAATCCCTGTATTCAATAGATTTAAAGTAAGGAATGATGTTAAATTAGCTAAACTAGATTTAGAATCAACTAAATTCCAACGGGAGATTGCCCTAAATAATTTAAGAGCTGAAACATCAAATGCGGTTTTTAATCTTAAGAATGCCAGTAATAATATTGTGCAATTGCATGAGCAGAACACAAACTTTGCCGAATCATTTCGCATTGCCAAAGTTGTATTCGAACTGGGGAACAGCAATTCCGTTATATTTTTAACGGCGAAGACCAAGTATGATAATAGCCAGATCCAGTTGGTTGTCAAGCAGTATGAATGGTTGCTACAAAAATATATCAATGATTATTACGCAGGCTCGTTAAATTTATAGTTATCTTAGTGTCTGAAAGAAGCCAGGGAATATGAAAAAAGCATCTATTTTAGTTGTCGACGATGACCAAGATTTACTCACAGCAGCAAGGATTTTGCTAAAACCTAAAGTTAACCATGTTCAAGTCGAATCTAATCCAGAAAACCTGATTGGACATTTGGAGAAAATGCCTTATGACCTTGTGCTTCTGGATATGAATTTCAAAAGTACCATCAATACCGGAAATGAAGGATTATATTGGTTGTCGCGGATCAAGGAAAAGTTTCCACAGGTTCATGTGATTATGATCACAGCTTATGGCGCCGTAGATCTGGCCGTAAAATCGCTGAAACAGGGAGCCGCTGATTTTGTGGTCAAGCCCTGGGAAAATGAGCAGTTGCTGGCCACAATTGAAAGCGTGCTGGCGGAATCGAAAAATAGAGAGAAGAAAAATAAAAATTCGCTTTTACGTTCAAGCAATACTCCGGATCTGATCGGTAACTCCCCGGTCATGGACGAACTGCAATATAAGCTGGAGAAAATAGCGCCAACGGACGCCAATATCTTGATTTTGGGTGAAAACGGTACAGGTAAGGATTTGATTGCTCAGGCGATTCAACGGCGCTCGTTACGCTCGGATCAGGTGTATGTGAAAGTTGATGTGGGAGCGCTGACAGAAACGTTATTTGAAAGTGAGCTTTTCGGTTATAAAAAAGGGGCGTTCACAGATGCTCGGGAGGATCGTCAGGGACGTTTCGAAGCTGCAAATGGCGGCACATTGTTCCTGGATGAAATTGGAAATATTTCTTTGCAGCAACAGGCCAAACTATTGACTGTATTGCAAAATCGACAGGTTACACCGCTGGGTTCTTACCAACCGATCCCTGTGGATATACGACTCATTTCGGCGACAAATGTATCCCTGAAACACCTGGCTGACGAAAGTCGTTTTCGAAAGGATTTGATTTATCGGATCAATACCGTGGAGATTCAGGTGCCACCATTACGTGAAAGAGGAGAAGATATTAGACTATTGGCCATACATTTTCTGGATATCTATGCCAAAAAATATAATAAGCGGATCGAGGGGTTTGAACCTGATGCCATAAAAAAGCTTTTTGCTTACCATTTTCCGGGAAATGTTCGTGAGTTACAATATAGTATCGAACGGGCGGTCATTATGGCTGATCAGGTAAGCATTGCAGGAAATGATCTATTTTTCTCACCCATTGAACAACAGGTGGAGCAGGTCGCTGTTGAATCCGTATCCAGTAGCCAAAATCTGGAAGAATTGGAACGGAAAGCCATCAAATCAGCCATCGAACGTTATAACGGCAATATCAGCAAAGCCGCAAAGGAGCTGGGGCTAACACGTGCCGCACTCTACAGACGTTTGGAGAAATACGATATCTAGTCTATGAGACATGGAAAAGTTTTAAATGTAATTAAGATTATTTTGCTTTTGGCGGCTTCGGTTGTCGGTGCCTACCTGTTGATGAAGCATGAGTACGTGCAGGCTGCATTGATCTTTTGCATAATGCTGTATCTTGGTTTCAATCTGTATGCCCAATATAATTTTTTGGAAAGGCAGCTTGTGGAATTTGCCGAAGCAGTCAAATATCGTGACTTCACACGACGTTTTTTGGTTAAAAATCCAAAATCGGTAGAAGGGCAGCTTTTCCGCGCTTTTAATCAGATTAACGAAACGTATAAGGAAATTAGCATTAAGCAGGAAATACAGCATCAGTACCTCGATCGTGTCATCAATATGCTTAACTCGGCCATTATCTTCTATGAAATGGACACGGGAAAAGTAATGTGGGTGAACGATGCCTTTAAACAGCTGTTTCATCTGCCACACCTCGGGAATATCGCCGGGTTAAAAAAGAAGAATCCTGACCTCTATGAAAAAACGATGCTGCTGGACAATGGCCAACAGCAGATGGAACCCATTCAGTCAAGCAAAGGAAAGATAAAATTGTTGATCCAGAGCTCTAGTTTTGAGACCCAGGATGCCGTATTCCGTATTGTCGTTTATCAAAATATCAATGAAGCTATCGACGAGACCGAGACAAAAGCCTGGCATAAATTATTACGTGTGCTTACGCACGAGATCATGAATTCTATTGCGCCGATCAGTTCGTTGGCCGAAACGCTCAATGGGCGTTTGGATCATTTTAGAGGACATGAGGATATTGAAGATCTAAAAACAGGTATATCCACCATCAAACGTCGGAGTGAAGGACTGCTGCATTTTGCAAAAAGCTACCGCATGATCAACAAAGTGGATCAGCCACAGCTGGCACCAATTCAGGTTTCCCAGCTATTTGAACATATCTATCAGCTGCTCGAGCCGACATTGATTCAAAAAAATATTGATGTCGATATTATCTTAAAGAATACGCGTTTGATACTTTATGCTGATGTCAATCTGATTGAACAAGTTATTATCAATTTGATGCTGAATGCCATCGATGCGGTAAAGACCAGGGAAGACGCATACATTAGTTTGTCCGCATTGGAAATAGACGGCAAGGTGCAGGTTCGCATCGAAGATAATGGTTCGGGAATTCCCGCTGATCTCCAGGAACAGATATTCACCCCCTTTTTTACGACAAAGAAAACAGGTACTGGGGTTGGCCTAACGCTGAGTAAGCAAATTATGTTGCTACATAAGGGCACCATTTTTCTTAACAGTGTGGAGGGAGAAGGCAGTGCCTTTATACTTCAATTTTAACGTACTATCACAAATACAATATATTCTTACCTGTAAAATTTTCCTGTGCTCCAGGTGGGGCTTAAATGGCTTGTTTCTGTCTTTGTAATTGAATGTTCCATGTGAAATAATTCGTAAAAGCGAAATTGCTATATGTAAAACTACGATCAACTATTGCCGGAATTTGAATCCGAAAAGTGCTTTTATAAGGCTGTAGATGATGAAATGTGTGGTATAGCGCACGAATTAAATTGTATATCAACGTAAATTTTTCGATGTTTGCAGCCAATGAACTACCACTTGAAGTACTGGCGCCATTATTTCATATCCCATAGCCGTCATGGGACACATTCTCCGTTTGTTTATAAATTGGTGGATGAAGTAATTTATCAGCAGGATGATCCTGATAGGATCTTAAACTTGCCCCGTGAGGTCAGCATGGGGGGGAAGGTGGAGATAAAAAAATATCTGCTGGTCGACCGTCTACTAAAAACTTTTGCCTATGATCAGTTTATGTTTTTGACTGATGAGCCTCCAGCGAGTTATGAGGAGCTATTTAAACAGAAGGCCGGAAGTTATTCTTTTAGGAAGATCTATTATATTGACCAAACAAACCTTGATCTGGATTTTCTGGCTGTTGTCGGTGAACGCGATATGCTGATTGTAAACGAGCCCCATTTGTCGGTCGAACGGGAAGAGTATTGGAACAAACTTAGGGATGATGATCGCGTGGTTGTCACGATAGATCTGTATCGAATTGGTTTGGTCTTTTTTAGGGCCGGACAACGAAAGGAAAATTTTCTGATCAGGTTTTAGTTTGTTCTCTTTACTTCCGACAAGCTTTGCGTAAAGTTTATTAGGTCTCTGAAGTTTTCCGCTTCGTTTTATGACCGGAATGCGGACATCTTATCAGCATAATACGCTCACTTAAAAAGGCGGACTTTACCTGGGGTCAAACTTATTGTGGTCACAGAACGAAAATAGCATCAATCAGATGCTTTTATTGCTATTTATGAAAAGGGAGGCGGTCTAAAGAGGGAGGCCATCAGCTGAGGCTCCCCCGTTTTTAATTAAAAAGCTTCGCTTAAAGATAGATAAAAACCAGACTGTCTTTTCTCACCCGTCCTCTGTTCACCATAGGAATAATCAAATCGGATACTGCTATTGTGCTCTAAGCTAAAGAAGTAGCGCAAGCCACCACCGTAACTCGGTACATATCTGCTGCTGTTTTCTTTTGAAAAGGTTGATCCAATTCCCGAAAAACCGACAATACCAAAACGAGGATGAAAGCGGTAACGTAATTCCGCTTGGGAAGCAAGGTAATTTTTGTCACGATAACGACCGAGGTAATACCCGCGCATCATCATGTCGCCACCCAGTTCACGGTAATTATAGAAAGGAACTGTTTTCCCGAATGTCGAGCGAAAGATCCCCTGAAGTGCCAGTGTGACTTTTTTATGCAATGGAATAAAGCCGCGAAGGTCTATGTCCAAGTTTGCCCCGTTGAAGTCTGTGCTGGTCCATAACTTAGGCGCGTAAGCAAGTCGCAATTTGGCATAATAACCACGGGTGCTATAGGAAACATTGTCTCGGTTGTCAAATAATTGAGATACGCCAAGCAGCAATTGTTGACCGCCCTCTTTTCCGATAAGACCCGATTGATTGAATATATGGTCGCTGCTATCGCTACGGATTGAAAAATTATCGTACTGTATATTGATGCCCGAATAAAGATGGTTGCCGACTTTTTTCTCAGCTTCCAGTTTTAATCGAAATAGCTTTTGATCAACCCTTTCTTCATCCTTCTTCCAGGTATCCATGCCGATGCCATAGTAATTAAATGGCCAGTTGCGGTATCGGATTTCACTGACGAAATGGTAATCGTTATTTTTTGTCCAAAGATCAGTTTGAAATTTAAAATTTGACTGATGTTTGGATGTAAACGTCCCCATGAGCGTCATTGTGGAGGTACGGATATGGGGATCAGACTTGTCCAGGTAAAAGTTGTATGAACTCGCTAATCCATATTCTACTCCCGTTTCCTGGGCGTAACCAACGGCCGGTAAAACCATAAAACTGCCTGATCGGGTGGAGTCTTTTTCAGCCGAAAGAAATTTTTTACTCAATTTTTGAATAATATTTTGAGCTTTCAAATCGCCTTTACCAGCTACAAATAGTGCAAGTAGCGCTGTATAGCGGGTAAGTTTTGAAAGTGATTGCGGTAAAATTTGCATGCCCAAAGATAGCACATTAGGCAAATAACCAAAATAGGCAAATAGTCAATTAAAAATTATTGTGCTGCATATCAGTATAATTGACAAAAAGTGTTGTTTTTTTTTGACAATTATTTTTGTAAAGTGAGTTTTGTGTCTATCTTTGCATCAGCAAACAAGGGAACAACGGTTCATAATAACGAAGTTTGCTTAGTTCTTTAAATGAAAAAAAAGTAAAAAATAAACTTGCAAAAATCAAAAGTAAATTCGATATTTGCACTCGCTGAAAAGATAAAGTTATCGGATTGGCGTTGATAGAACGTAAGTTATTTTAAAAATATTAGAAGCCTCTTTAGCTCAGCTGGTAGAGCAACTGACTTGTAATCAGTAGGTCATTGGTTCGATCCCGATAAGAGGCTCTAAATGTAACGAAAGTTACAGGTCTGGAGGGGTTCCAGAGCGGTCAAATGGGACGGACTGTAAATCCGTTGCTTCGGCTTCGAAGGTTCGAATCCTTCTCCCTCCACACTTTTTTTAATTGGAGTTTAGATTTACTCTAGTTTCTAGTTATTAAGCGGAAGTAGCTCAGTTGGTAGAGCGATAGCCTTCCAAGCTATAGGTCGCGAGTTCGAACCTCGTCTTCCGCTCAAATTTTTCAAGTATTAAATTTAGTCTCTATCTTCTTTGATAATAATGTATCTAAAGGTGGGGGCATTAATACGTAAATAAGGTTTTTTAGTAAGCCGAAGTAGCTCAGGGGTAGAGCACTTCCTTGGTAAGGAAGAGGTCGTGGGTTCAAATCCCATCTTTGGCTCGTACTTGTGTAAAAGTTAAGCAAGAGTATATAACAAATAGAAATAATTTATAATTACTAATTCGCATAAACATGGCAAAAGAGAAATTTGACCGTAGTAAACCACACTTAAACATTGGTACTATCGGTCACGTTGACCACGGTAAAACTACAACTACAGCTGCTATCACTAAAGTGTTGGCTGATAAAGGTTTGTCAGAAGCTCGTTCATTTGATTCAATTGACTCTGCTCCTGAAGAAAAAGAGCGTGGTATCACAATCAATACTGCACACGTAGAATATTCTACAGCTAACCGTCACTATGCACACGTTGACTGTCCGGGTCACGCTGACTACGTTAAGAACATGGTAACTGGTGCTGCTCAAATGGACGGTGCTATCATCGTAGTTGCTGCGACTGATGGTCCTATGCCTCAAACTCGTGAGCACATCTTGTTGGCTCGCCAGGTAGGTGTTCCTGCGTTAGTAGTATTCATGAACAAAACTGACTTAGTTGACGACCCTGAGTTGTTAGACTTAGTAGAAATGGAAGTTCGTGAGTTATTATCATTCTACGAATTCCCAGGTGATGATATCCCTGTAATCAAAGGATCTGCTTTAGGTGCATTGAACGGTGAGCCTGAGTGGGTTGAGAAAATCATGGAATTAATGGATGCTGTAGATAACTACATTCCAATTCCTCCACGTTTGACTGATTTACCTTTCTTGATGCCTATCGAGGACGTATTCTCAATCACTGGTCGTGGTACAGTTGCTACAGGTCGTATCGAAAGAGGTGTAATCAACTCTGGTGATCCAGTTGAGATCTTAGGTATGGGTGCTGAGAACTTGAAATCTACAGTAACAGGTGTTGAGATGTTCCGTAAAATCTTAGATTACGGTGAAGCTGGTGATAACGTAGGTTTATTGTTACGTGGTATTGAGAAAACTGATATCAAACGTGGTATGGTTATCTGTAAACCAGGTTCAGTAACTCCTCACGATCATTTCAAAGCTGAGGTTTACGTATTGTCAAAAGCTGAAGGTGGTCGTCACACACCATTCTTCAACAAATACCGTCCTCAATTCTATTTCCGTACAACTGACGTAACTGGAGAAATCTCTTTACCAGAAGGTACTGAAATGGTTATGCCAGGTGATAACGTTACGATCTCTGTTAAATTGATCTCTCCTATCGCTATGGAAAAAGGTCTACGTTTCGCTATCCGTGAGGGTGGTCGTACAGTAGGTGCTGGTCAGGTAACTGAAATCATCTAGTCTTTCATAAAGATCTAGAATCACATAGAATAAGCTAATCAACTGCTGTTGATTAGCTTATTTTTTCGATAAGCGATTTATCGGATTAAAATAAAAAAAAGTAAAAAAAGATTTGCAGAAAGTGGTTTAAAACACTATATTTGCATCACAAAATAAGAAATACACGGGCATAGTTTAAAGGTAGAACGAAGGTCTCCAAAACCTTTGGTCTGGGTTCGAGTCCTGGTGCCCGTGCTTATAAAAACAGATAAACTAAAATGGCAAAAGTACTTGATTTTTTTAAAGACTCTTACGTGGAGATCACTGAGAAAGTGACTTGGCCTACGTGGTCTCAGTTACAAAGTTCAGCTGTTATTGTGCTTGTTGCGTCTCTTCTTATTGCATTGGTTGTCTTTGTAATGGATAAAGCTTCAAGTGTAGGGTTAGAATTCTTGTACGGTATTGCTTCTTAATTTTTCAATCGTATTTATTTATGGCAGATCAAGGTTTAAAGTGGTACGTAGTTCGTGCTGTAAGTGGTAAAGAAAAGAAAGTAAAGCAATATATTGATGCCGAGGTTAGTCGTTTAGGTATTGAACACTTGGTTCCTCAAGTGTTAATTCCAATGGAGAAATACTACTTAATGCGCGATGGCAAGAAGGTTGCTAAAGAACGTAACTACTATCCTGGTTATGTTTTATTGGAAGCCGCTCTTGACGGAGAGTTAGAACACGTCATCAAAAATATCAATAGCGTAATTGGTTTCTTGGGAGACAAAGCTGGTAATGCTGTTCCTTTGCGCCAAGCAGAAGTAAATCGTATTCTAGGTAAGGTAGATGAAATGGCCGAGCAAGGTGAAACCATTAATGTTCCTTACTATGTGGGCGAAACAGTGAAAGTAAACGATGGCCCTTTCAATGGATTTACTGGTGAGATCGAAGAAGTTCATGAAGATAAGAAGAAATTGATCGTCATGGTGAAAGTCTTCGGTCGTAAGACTCCGCTGGAGTTAAACTACATGCAAGTAGAAAAAGAGTAAGATTAGTAATTAACGATAGAGAAAAGCTTTACATGAAAATGTAAGGCTTTTTTTTTATTTTTTCCTCTTTTATGTTATCTCGGACTGATGACTGCTTCATCAGCACCGTTCTTTGTAAAGAAAATGTTAAAAGCGGTATCTGTTTTTTTTTGTAAATTGAACTGCCGGTCATATGTTCCCAGAACCTTTTATAAAAATTATGAACTATGAAACCAACAAAAAGTCGATTTTTTTGTAGAGAGGCACAACGTTCAAAAATGCTTTTCGAATCGCAGAAAAAGGCCGAAAACTTTATGCAATATAATAACAAAGAAATTCTGAACGAGTCAGGCTATGCTCCCGTAAGATCTTATCATTGTATCGCATGTGATGGTTGGCATCTGACGAGCAGACGCGAGGAACTGGACCTTCCTAGCAAAACAGAATTAGTGCTGGAAGCCTACAAGGAAGTGACGGATGAGAAAGATAAGGCAAAAGAACTTCGTGCCAACGGACGGCAAGAAAAGGAAGCTCCATCAGCAAACGCTCTTGAGGGGCTGCGAAAGAAAATTGAGCTAATAAGACGTTCTCTAAAGAATAAAGGAAGTAAAACTATAATAATCAAATTAATAGAGGGAGCTTCTAGGAGCTTGAAAGACCTTGAGGTTACAGGCCAGCTCAAAAAATCGAAAGGAGAACTGGAAGTTCACTTAGGCAGGCTTGAATCCCGAGCCATGTTATTACCTGATGACGAGGAGGCTGGTATCCAGACACAGATCCGCGTGATAGAACGTTTATTTGATAATGAAAGCAATCGCATATTAATACGTAATCTGATTTATGAAGCATTGCGGACATTGCGGAATATGGATGGTGCTATGCTGCAGCAGGATTCAAAGAAGGCGCTTGAAAAAAAGCTAAAGAATCTTGCGCTCCGCTGTGATCATTTGCGCAATAATACATCCGGGTAATACGGATGCTTTGTACATGGAATTGTTCATTTCGGAATTTCGTCCGAAAACCGTCCGATTTCATCGATTACTTTTTTCGTTTTTGGCTAAGTAGGCTAGATTGGTAAAAAACTTTTGAAGCAAGTTTTAACCAAATTTGTTAGCCTATGCTAAAGAGCCAAAAAAATAGACCTTATTACATCGTATGGGAAGATGGAAAATGTCACGCCATGGAGCCGAGCTACACCACCTATCGCTATGATTTACACTTTGCTACTGGTAATACTATTCAGCTTGCGGATGATGAAGCTGGTAGGCTGATGAGCCAGTATTATTTTTACGATTCATTCTTTGTCGATCTTATTCAGGTTGAAGCCCTTGTACCCTTCCGTTTTAATCTTAATGTACCCGAGCGATTTCTGTATTTATTTTTTATGCTGGAGGGCGAGTGCAGCTATGGCGGAATTGATAAAATAATATCGGTCACTGCAAATTCGGTGACGCTAGAACATGTCAATCATAAAATTCCGATAGGCCCGATATACGCTGAGGCCTTTCTGGCACATATCGCATTTTTTGGATAAACTAGGCTTCATGAATATCGGTATTCTTTTTCTTAAATTGCTTTTTTGTTTTTTTCCATGCAATCATGATATAATTAAAGAGCAGCCCGAATATATTTTCTCCGGTTATATCGCTTGCTAGGGCAGGCGGCAACAATTCATAGATCGTAATGCCAAAATAGTCAGCTATCTTGTAAACTTGCTCCACTTTTAGTTTAGTCTCATTTCGTTCAATTTTTGAATACGCTGCCTGTGACATGTTCAAAATAAACGCAACAGCCTCTTGTGATATCTTGAGGCTCTCTCTTTTCTGTCTGATAATAGTTCCGATTTCCTCTTTTGCCATTCTTTTCAATACCCAAATAAGAAGGCCTAATTTAATAAATATAACTTGAAGTTGTAAGTTTTTCTATGATAAAACTGGTGGTTATAGGATATAACCTCAGGTTGTGGTACCTAAACTGCTTTTCTGTGAATTTTGAAAAAATAAAAATCAGATATCATGGAAAAAAAATTAAAAGAAATTAACGTAAGAGAATTAGATGAAAAAGAAGTGGTGGAAATTGAGGGGGGAACTGAAAGGGAAAATTCTAAAGATGTAAGTTGGTTTGAGTCAATATTGAACTATTTTAAACCTTAAAAAGCATCTTTCAACTCGAATGTATAAGGGCTGATTATGAGTGCTAATATAGAGCCAAGGATAAATGCGACTAAGTGTAATGGTCTATTTATTCTAGAAATCTTGATGAATGAAAGTAGAAAAGATATTAATAACATATATAGCCAATAATGTGTGGCATTATGAATCCAAGGTATAAATAAATGATTGATTTTTTGCAAAGGGAAAAATAGTGTGGAAAAACCGAATAGTGCAGAGGAAAGGCCTGATGCACCAACAGCCGTAAACCTGAAGTCTTTCTTTTTAAAAAGTGTTTGAACGAAATTAGGTACTATTATAAAAAGAAGAAAAATCAATATTGTGAACACCTGTGCAATGATAATACTATATGCTTGATTTAAGACGGCAAACATATCATACCCTAATCCAAAAATTACAATACAATTAAACAATAGGTGAATCCCGTTGCGATGAACTAATGCGGAGGTAAGCAAGGTATGAATACGCTTACCTCTTGCTATTTCGTAGGGGTGCAGGATCAGTGCATGGAAAAATGGTTTGTGATAAAATCCAATCATGCTGCAGGCCAATATAATCGGAACGACGATATAGGAATATGGAGCTTCGGAAAAAGTTGGAAATATATCAAAAAATTTCATCAACGGCCATTAATTGTGCTTCCGAAGATAATTAATAAATTTTAAAATACAACCTCAGGTTGTGGTGGGTGTTCGGGCTATTGATCAATTTTGTATCGTTGATCAAAACCAAGATGAAAAGAACAAATATCATATACTTACTGCTGATAGCGGCTATAGTGATAGGGCTGATATTATTGCCGTTAATCAAGGTGCCGATCTCAATTTCGGCACAGGGGATCATTAGGCCCAAGATGGAGAATGCAAAAATACTCTCTTTGGTCAGTGGTCGCATCATTGACAATCGTATCGTGGGCAACAATCAGCAGGTAAAGGAAGGGGACACTTTACTGATTGTCGTCTCTGAAGATCTGGAAAATAAGCTGTCCTTAAATAAGGATTTGATGGCAGACTATTCACGACAGATTGCTGACCTGAAACTCATTCTCGCGGGAGACGCAAAAAACGTGCAAGGTGGACAATACCAGTTGGAATATCTATCGATGGAGCAGCGGATGTCCGAAATCCAGTCGCAACTTACATTAGCACGCCGCGAACTGGAGCGTAATAATAAACTATATAGCCAGGGGGTGGTGTCTCAAGCTGAGCTCGATAAGACCAAATATTCCTTTGAACAACTGGAAAATCAGTTTCTAACAATACGCAAACAACAGATGGCGCAATGGAGTGCTAAGCTGGTCGAATTGCAACAAAAGGCGCAATCGCTGTCGTCTGAGAAAAAGTCTATCTTGATTGATGGTCAAAACTATATTGTTCGGGCACCTATCACTGGGACCGTGGTCAATTTTAAAGGGTATCAAAAAGGAGGACAGCTGGTACAGGGTCAGGATATCCTCGAAATTTCACCAGAAGATCAGCTTATAGCCGAATGTATGGTGCCTACCAAATCCATTGGCTACATCAAAAACGGTCAATCGGTAAAGTTTCAGATGGATACGTATAATTATAACCAATGGGGATTTCTGTCGGGTACAGTGCATGATATCGACTACAATTTGGTGACGGATCAGCAGCAGGGATCTTTTTTTAGGGTCAGGTGCCGCATGGATCAAAATTTTCTGGGCTTACCCAATGGTAATAAGGTCTTTGTAGGAAAGGGGAATACATTCAATGCCCGATTTTATCTCTTGGACCGTACCTTATGGCAGCTCCTGTTTGATCGGGCTGATGACCTGTTCAATCCAAACCTTGGCGCTAAAACGAGCGCATTATAAAAACTTCTCTATTATCTGACAATAATAATTTGTACGAATGAAAAAATCACCTGTTTGTATCAAACAGCACGATATCCGTGACTGTGGAGCGGCTTGTCTGGCTTCTATTGCAGGCTATTATGGCACGCATATTCCCATCGCCAAGATCAGACAGTATTGCCATACCGACACGCGTGGTACCAATGTATTGGGGATGGTGCAAGGACTGCAGCAGATGGGTTTTAATGCCAAAGGTGTCAAGGGCGCAATGGATGCTATTCCGCAGATCCCGCTTCCGGCAATTGCTCATGTTGTACTTAAAGAGCAGCTCCAGCATTATGTGGTGATCTATCAGGTTGAAAAAGATAAAATTACGGTGATGGATCCCGGACTGGGAAAAGTGGAAAAATACACATTTGAGGCCTTTCAGAAGATCTGGACCGGGGTACTGATATTAATGGAACCTAATGAGTACTTTGAACAGAAAAATGAAAAGACCGCCGTTTATAAAAGATTTTGGAATCTGATCAAGCCGCATCGCTCGGTCATTGTTCAGGCGCTGGTCGGCGCTGCGGTGTATACGCTGCTGGGACTTTCAACATCATTTTACATTGAAAAAATTACCGACTATGTGCTGGTGGATGGCAATGTACGCCTACTGAACCTGCTTTCTATCGGTATGCTGGTCATTCTGGTTTTTCAGCTGCTCATTGGTACATTGAAAAGCGTGATGGTCTTACAGACGGGACAAAGGATCGACAAGTATCTTATTTTAGGCTATTATAAACACTTGCTGAGCCTTCCGCAGCGCTTCTTTGATACAATGAAAGTCGGCGAGATTATATCGCGGGTCAATGATGCGGTCAAAATTCGTGCTTTTATCAATGATGTGGCCATACAGGCTGTGGTCAATGTGCTGATCGTGGTATTTTCCTTTGCGCTCATGTTTACTTATTTCTGGAAACTGGCGTTGATAATGCTGCTCGTTATCCCCTTTTATCTGGGGGTATATTGGCTTTCCAATAAACTAAACAAAAAAGTAGAGCGGCGGATGATGGAAGAGGGAGCCGAACTGGAATCGCATCTGGTCGAATCGCTCAATTCGGTCAAGACTATCAAGCAGTTTGGTATCGAAACTTATTTCAATAGCGGTACAGACAACAGGTTTTCGCATTTGTTGAAAACAATCTATGCCTCGGTGATGAATGGATTGTTTTCCAGCACCTCTGGTGAATTGTTGTCGCGGCTCTTTACCATTATCCTCTTATGGGCAGGCTCTTATTATGTGATCGAACGTACGATCACACCGGGCGAACTCTTATCCTTTTATGCGTTGATCGGATATTTTACCGGGCCGGTGACACAATTGATCGGAATGAACAAAACCTTGCAGAATGCATTGATCGCTGCAGATCGGTTGTTTGAAATCATGGATCTGGAGCGTGAGGAATCCGAAGAAAAATTACAGCTGACATCGGATCTGGTTGGTGATATCGTATTCGATAATGTCCGTTTTTCCTATGGATCGCGGGTGGAGGTATTCCGCAATTTTAGCTGCCGAATAGAGCAGGGGAAAATGACAGCTGTGATCGGGGAGAGTGGCAGCGGTAAGACCACTCTCGGAGCACTTATCCAAAAACTGTACCCGCTACAGGAGGGCAAGATCTCCATTGGACAGTACGATCTGAATTATATCTCAAAGAGTTCACTTCGGGAACGCATCGCCATAGTACCCCAGCAGATTGATTTATTTTCGGGTAACGTCATTAGTAACATAGTCGTCGGGGAGGATATCCCTAATTTTCAGCGTCTATTGCAGGTGGTCAATGAATTGGACATGATGTCTTTTATCGAAAAGCTACCTGCTGGTTTTGAGACACAGCTGGGTGAAAACGGGTCTATGTTATCGGGTGGACAGCGGCAACGTATTGCCATTGCGCGTGCGCTATATCGTGATCCGGATATTCTCATTTTAGACGAAGCGACTTCGGCCTTGGATACATCAACGGAACAGGTGATTCAACGGGCTTTTCGCCGCTTCAAAGATTCGGGTAAGACGATGATCGTCATTGCACATCGGCTGAGCACCATTGCGGAAGCGGATACGATCCTTGTGCTTAAAGACGGTGTACTTATCGAACAGGGGGAACATAAGCAGCTACTGGCGCAGGAGTCGGTTTATAAGGATATGTGGAAAAAGCAATCGATCGTGTTAAACTAATCTAGCCTATTATTCAATGATGAACATTTATCGAAGGGAGAGTATAAAGTATTGTCTTATTCTTATATGGGTAATGCTGTCTGTGGATGTGCTGGCACAACAAACCTGGACTTTGCAAGACTGTATCGATTATGCGGTGGAGCATAATCTGCCGATCAAGCAGCAGGAAATTAAGGCTGCGATAAAGGTGTTGGATCAGGAAATGGCACTCCGTGAGCGTTTGCCAAGTGTCAATGGCTATGCGAACGGTTATACCACTTTTGGATCATCACAGGATGTGTTCGGTACGATCCGGCGTAATGATAACTTGAATAGCAATATGGGGATCAACGCGGAACTAACCCTTTACCAGTATAATTATTTTCGCAATCAGGCCAAAAAAGCAGCTTCTGAAGCGGAGCAGGAACGTATCGAGAAAGAAATATTGAAAAGAAATCTTACCGTTCAGCTGATGGAAGCCTATCTGCAGACTTTGCTGGCTCAGGCGCTATTGGTATCACAGGATTCGGCCATGCAGTTTTCAAAGCAGTTATTGGATAAAGCCGAGAAAAGTACGGCGGTGGGAGCAACAGCTGTGTCGGTAGTTGCAGAAGCAAAAGCCAATCTGGCACGGGAAAGGCAGCAATATCAGCAGTATCACAAAGATAGACAACAGTCCTTGCTCAAATTGGCTCAATTGATGAACCATCCAGATTACAGTAGTTTGCGATTGGCGGTCCCGATAACTGCGCAAGATCCGCAGCATGACAGTACTTTTTCGGAAATATCGAACTTGCGGGAAGAAGCCTATTTACATAATCCAGTATTTGCTAAACTCCAAAATCAAAAGGATGGACTTGACCTCGAATCCAAGCTAATTAAAGCAGCACTATTTCCGACAGTAAAAGGATCTGCTGGTTTGGGGAGTACATATTTCAATGCGTTTAAAGCAGAGAATACGCGGTCTTTTTTTGTGCAGAGCAAAGATAATTTTGCCCAGCAGCTCGCCGTAACGGTTTCGGTACCCATATTTAACAAGGGGAAAACAAAACGGCAGTTGAAGCAGATCGAATTTAACAAGCAAAATATCCAATTGTCGGCCGACAATGAAAGGCTCGCTCAGCAACATATCCTAGACAAGCTATTGCTTGAATTGGACGAGAACAGAAAGCAATATGGTATTGCGGTAGAAGCGAGCACGGCAACGGAGCAATCTTTGGATTACACCTTGCGGAGTTTTGAGGCAGGCAAGGCATCTATTTACGACATCAATACCAGTAAAAGTAATTTGATCAAGGCGGAGTCGGAAAAGATCCGCAGCAAATATAATGTGGTGTTCAATCAGCTGCTGCTACGCTACCAGATTTATGGAACGATAAATTAAATTATATGAAGTTATTCCAATATATAGACCGGATTAATTTGTTGGACAAGTTGATCAGGCGGAGAAGGACGGGGACTCAGTCGGAACTAGCGATTCGACTTGGGCTTTCTGTATCGCGATTGGCCCGTATTATTGAATATCTCAAGGATATAGGTGCTCCAATTGCTTTTGATAGATCGCTTAATACGTATTATTATGAAAAAGAATACTCAATACAAATCAAGGTAGAAGTTCAGCAAGAAAATATCCATTTGCTAGATCTAAATCAAATGAGGCAAGCAAATGCGGGTGACAACTTTATTTCAATTCATTTATTGAATGCTTTTTTTGTGCATTGAGGAAAAGTAATTTAGTAGTATTAAATAACAAAGCAGGAATCCGAAAAGGCTTAAAATAGAGTAGGAGCTAATTTTTTATAAATCAAAAAAATGAATACATTAGATTTAAAAGGTTTCGGTGTTCAAGAGATGAATGCTAAGGAAATGATGGAAATTGATGGTGGACAGCAGACACGCGTAGGTAAATGGTTGAAGGCAGCTGGGGAGCTAGCTGTTTGGGTTGCGGAAACTTTTTTATAATAGTTATCTAATTTGGTGTGGCATTGACTTTATTTGAGTAGATGCCATACCATTCGTTTAATGGTTTGTATGAAATATATATTATTTCCTGTTATTAAAATACATAAAAAATATAATTTTTTATTTTTTTTGCTGTTTTTTTTTATAGATACTATTCTAAGTTACGGTTTTACGCAGATCATTAATTATTTTACATTTGATTTTGGTGCTGTAGAGTCAGTCGCTAATGTTCCTAAGTGGCTTTTATTTGTAATCATGGTAATATTTGCTCCACTATTTGAAACAATAGTGTTCCAATTTGTCGCGCTGGAGTTACTATTAAAGCTAAAGATTTCGCCCAGTATAGCTATTGTTGTTAGTACCGTTATCTTTGCATTATTTCACAATTATAATATTCCATATATGGGTTATATTTTATTGACGGGTTGGATATTACCGTATTACTATATGGCTCTACGGGATCAAGGGAAAAGCAATAAAATAGTATTTGTTTTTATGCTTCATTTGATAGGGAATTTTATTTCATTTTTTGATTATATATAAGATGGGTAATTTAGTACTTTCAAAATAAAAACTATTTTACGTAAGAACCTAAGTACTTTACTACTTAGGTTCTTCCTAAGTTTGATTTATTGAAACAGAAAATAGAACTTTTAATATTTGGTACCTTACAATCAAGTATTATTTTGATTGTGTTTTTTCTATTGTTTGGCTTGGATATAGCTTCCAACACTATTACCATGTCTGATCAATTTAATATTTTTCTAATATGTATCTGTTCAGCTTTTTTTGAAGAGATCATATTTAGATATTATTTGATTAAAGGTTTAGGGAAATCTTTCAGTAGAAAAAAATCAATAGTAATTTCCAGTTTGTTATTTGCTATTTGTCATTTGGCAAATTCTAATTTCACTGCCATTGCTTTTTTTTCCCATTTTTTAGGCGGTATTATTTATGCCTATGCTTATATGCAGACAAAATATATATATTACCCGATAGGATTGCACTTCGGATGGAATTATGCTCAATGGTTATTTTCGCTCCCAATGAGTGGAACGATAAAGGAAGGTTGGTTTAATCTTACTTTTCCAACCGTCAATTATTGGTTTGGAGGAGCCTATGGAATAGAAGGGGGGCTTGCAAGCCTAATTGTTCGGGGGCTTTTGTTATGCCTTGTTGTATTTACTGTTTCTCGCTATGATAAGAAATCTATTAATGACAATTTGTAAATAAAAATGCTAAATATTCTGTTAAAATATTTCAAAATACAACTTCTGGTTATAGTTTGTACGGGAGGTGTTGCCTATTTTTGGAATAGTAAATCAAATCTAAATCATCAAGTCAAATTTTCATTCTTCTGCATTCATCAATCGATTAATATCGAGAAAACATAATGATTATCTGGAGCAAAAATAAACTTATGAATGAAATAAAGAATTATTCTGGGTTTGTTGTAGAACCGAGATTGATTAAAAAAATTAAGCTTAATACGCTTAGTTTTTGAATATAATAATAACCGTGTTGGAAGATAGCGAATCGATTTACATTTTATATCACATTGATAAAAGCTTAGATGAGAAGAGCGAGAATTTTTTAAGAGTTTTCTGGAAATTATTCCATTTGTTTATTGCAAAAATCGATCAATATTTTTATTTTTAGATTCCTAAGTTTCTAATTCATTATCAATGTATGGAGAAGTTTTATTTGTTTTTTGTGTCTCACAAGAATTTTTGCTTTTTAGCACTCGCTTTCATATTTATTCTTTATAGGCTGGGTTACGTTCTAGGCGGAATGTTATTCAAATACTTTCCTATATAAAATGAGTGAAGGAACAAAAAAAATATGGAAAAATGTGCTAACTGTTGTAGCCATTGCTATATTAGTGTATTTGCTCCAAATTGATATTGATAATTTGATAGTGAAGATCAAAGAGCTGTGTCGATAGCATGCGTATTTGAAGGAGAGCATAAAAATCACAAGAATAAATTGATAAGAAAGAAATGAGGTGATTGATAGGGAATGCTGAGTTTGCTTTAGGATATGAAATAGGGGGAAGTGCAAGCCAGTAAAAATATTGAGGATCTTCACCTATAAATAAAAGTGGTATGCGAACGATTCCCGATATTTCATAAAAAACGCAAATAGAGAGTATATTGGTGAACAAAAACATTCTTCAATTAAGTGTAAAACGTAAATATGTGGATGCATTTATATGCTTTGGTTTTCTATTGTTAATAGCTTTTTATATAGGTTATAGAATAGGGAAAAATACTGCTGAACGACAGCGTATTGAAATAGCAAATTGAATATTCATATATAGCGCTTTTTATTTTTTCTAAAAGTGCATGTTTTCAAAAGGCACCGAGAACTTTTTTCATGGAGTTTTTTCTTTATTATCGGCATTCAAGAGCTCATCCGACAAAATTCGGGTTCGGTTCATGGCTGTTGGTTTTTTTATTGGAGCTGAAATTCGTATGTATGTTGCTAGTTAATTCGTAATAATATGAAAATTGAAAATATGTCATTGGTTCCACTTACAGAAGTGGAAATGCAGGAACTTGATGGTGGAGGTATACCTCTGTTGATTCTAATGATTTGTTGCGGGGTTGGCGATAGGTTTAGCGTTAACTTAACATGAATTTTAGATAGCATTGTTGGTATTATCTAAAAAATATAAACAATGCTATCTTTCTTGATTTATAATGCATCGTTATAGAGCAAACAAGTACTATTGAAAAGCAGTTGTTATATTTGGTGATTTAATGATGAACATCTTGATTAAATTAAGTCCACACTGTGGCGGTGTTGGTTTTAGATAATAATAAGCAGATGTAAAGCTAGAAATTTATGAGTGAAATAGAGAATTATCCAGGATATGTCGTAGAGCCACGATTAATTAATTTGTATAAAGCCAATGTAGTTGGTTTTTTGTTCTTTGCTATTTTTATTTTATTATATGGACTGCCTTTTTATTTGTTATGGGATATAAAGGAAAGTTTTTCTATAATGAAAAATAATATTTATGATAAGGATTCTAATGTATGGTGGGTTTATGTAATTATTATTGTTTCGGGTATCGTTATTCATGAATTGATTCATGGTATTGTATTTGCATTTTTCGCCAAAGAGGGTTTTAAATCGATAAAATTTGGTGTTTTATGGAAGATGCTCACGCCCTATGCTCATTGTAAAGAACCCCTACAAGTTAGGGCTTATATGCTTGCTCTTGTTATGCCTTTTATTATAGTTGGTTTATTGCCAGGTATTTATTCAATTTTTACGGGGAATTTGCCACTATTACTTTTTGCAATTTTTTTCTCAGGTGCAGCATCAGGTGATTTCATGATTTTAAATTTAATTTATAAAGAGAATAAAGATAACCTGGTACTTGATCATCCTACTGAGGGAGGGTGTTTTGTTTTGAAAAAGGTTATGTAATTTAGCGGATTTCTGATTACGAAGAATATCCTATCTGAAGGGCTGGTCTAAATACCATGTAGCTAGTTCTTAATTTCTTCCAATGCCTCCAACCCAACTATTGTAATAAGAGATGCCTTGATCCCGTATATTAATACGCCATTTTGCTACTTATTTGCCAAAAAAAGAAATTTATTGCAATACAACCACAGGTTGTGGTACAAATATATCGTAATGTTTATTTTTGGTACATAAACTAAAATCTAAATCATCATGAAAATTAAAACACTTTTAAAATTTGTAGGTATAATAGCTGTTTTGGCATTTTGTGTATACCTTCTATCTAATGTTGGCGAACTTATTCGAGGATTTGAAGATGGTTTGAATGCGGCCAGAAATAAATAATAATCTTATATTAATATACATGAAAAAATATTTTATTCTCCTAATACTCTTCTTTTTTGTCACTTCTGGTGGCTTTGCGCAAAGTAATTCGATGCTATGGAAAATCTCGGGAAATGGCCTGAAACACGATTCCTATTTGTTTGGTACGATCCACATGTTGTGTCCTGACGATTTTGAAATCAAACAGAAATGCCTGGATGCGCTTAACTCAAGTGAGAAAGTCGTGTTTGAAGTTGATCTGACGAAGCCTGAAAATCTACAGATCATGCAGGCTTTCGCCGCTCCGCAGCCTGATTTTATAAAAAAATTTACTGAAAGTGATATAAAAAGTATGGATAGCATCTTGGTGCCTCAGCAGCTTTCCATTAAACTATTGGATTATGTATCGCCTGTCACGGCCATGTCCTTATTTGCAATGAAAGGTTTTAACTGTCCGGATCCAACCAAGATCAAATCATTTGAGGCCGAATTGGCAGAGATCGCAAGAATAAAGGGAAAGTCAATTGGCGAACTTGAAACTCCCGATTTTCAATTCAATCTATTAAAAGATTTGATTACGCCAAAGTTATTTATGGAGTCAGTGTTTCAGTTGGATAAGTATCCTGAGCTGACAGCTAAGATGGTAGCCGCCTATAAGAATGAAAACTTAACCGAGTTAACGGAATTGATTCAGGATCCGACTTGGATGACAGCTGAACAGAAAGAAAAGCTCTTGGCAGGACGGAATGTAAACTGGACAACGATTATTCCGAATTTAGTCAAGGAGCAGAGCTGCTTCGTTGCTGTAGGAGCTGGACACCTGTCTGGTGAAAAGGGGTTGATCTCATTACTTAGAGAAAAGGGTTATAGCCTGACGGCAATTAATTAAGGTGTTATTTTTTAGATATAAAGTAAGTAGTACGTTGATAGGGGGGGGAGACTAAATTATGTTGTTGGCAAGGAATCAAATGCTGCTTCGTAATTTAATGATGTTAGCTGTATAAAATGAGCGATATTTTTAAAGTAATAGCAATACCTAAGCATAGAAATCTGTATTTTTTTCTGGTATTCTTTTTAATTGAAGAAATGACAAATTGGGGTGCGTATTATCTTTTTGATCATTTCTCGCCAGGTTTTGCTGATATTGAGGAATATCATAAACAGGGATTGACATTTACATTTGTGTTATTGGTGATTGTGGCGCCGATCTTGGAAACTTTTTTTGCACAATTTTTTATATTGGAAGTATTACGTAAATTAAAAGTTTCCGCTTCAATTAGCGTTGTTATTGCAGCTATTGTTTTTGGTTTATTTCATTATTATAATATATGGTATATACTTGCAACTATTATTTCAGGGTTTGTATTTGCTTATTATTATATGGCATTACGTCCACAAGGAAAATGGAATAAAATTTTATTGCTGATTGCACTACATGCCATGGCCAATATAGTTGCTTTTTTTAGTACTTATGCTTAGTCGAAGCTTCTCTACAATATGGGAATAAGGTTTATTATTATTCTGATTTGTCTGCTCGCAAATCTACAATCCAAGGCTCAGATACAGTTTGTAGACGAGCAGAAAAAATTGCCCATCCCGTCGGTAAATGTCTATGATGGAACAGTAACTAAAATCTAAAGTAGCATGAAAATTAAAACACTTTTAAAATTGGGGGCTATAATAGCATTGATAGCATTCATTGTTTATGTTTTTTCTAATAGCAGCGCGCTTATCGAAGCGTTTAATGAGGGATACAATTCAACAAGGAATAAGTAATGTTGGCTGATTCCTAATATGACTATTGTTATGTTTAACGTTCAGCCATGTTAACAAAAGATAAAATAAAGTTAGTTGGTTATTTGTATCTGCTATTTATGGGAATTGGCATGGTACTCATGTTAATCATTAAATCTGTTGATACTTTTTTGGTAGTTGATTATTATAAATTGCCAAGTCTGTTGAATCATGATGTGTTTAGATCGATCAGGGCTTTAGCGCATAATAATAGCTTTTATATAATTTTATTGGCTGCTTTCTTTGCCCCGTTAGTGGAGGAGACTATGTTTCGTCTGTGGCTGTCTTTTGATCCACGGCATATAGCGATATCTCTTTCTGTTATTTTAATCTATTCCCTGTTAGGCTTTAAGAATTTATTTAAGATGAATTTAATGACCTTGGCCATCGTTTCATCTTTTTTGCTGATCTGTTTGTTGACCTATCAAATACTGAAGGGTATGAATATTGAACAATTTCTAATGAGGATTGTTTCAATAAAGGTTCTGGGCTCAATAAGTGCCATTTCATTTGGATTAGTGCACATAGCAAATTTTGCCCCTATTAATACGAGTATTTGGTTTCTTTATCCTATTTATGTACTTCCACAGATCATCCTTGGATATTTGACAGTTTTTCTAAGGGTAAGGTATGGATTTATATATGGGGTGGTGCTGCATGTGTTGGTGAATTTTGTTGCTGTTCTTGTGAAAATTTAA

Protein sequences of DBSCAN-SWA_2

>NZ_CP049333|1117571:1194056|1149530_1151933_-|WP_108635866.1|DBSCAN-SWA
MIKNYIKTAWRSIRANRFFSILNISGLAIGICVSLLLFAFIRQELSFDTMYTKSNNIYRLHMQLSAEYNREKMINLPNAVGPALKSDIAQVDNMVRLVKDGFGATASIRAGEENFNERQLYLADSTLFSIFDFQFIEGSVHTAFLNKKSIVLSQSTKEKLFGNSEALGKLISINQRDTVQVTGVFKDLPANSTLDCNMVMNIMDSWMGQNVYWSNASYETYILLKKGADPAIVAQEATKLIDKYVEKDHRYFTEFFLQPLLKVHLYSSNLGEGVTKRMGNIDTIRTLSILAFLVIVIACINYMNLATAKSQKNAKEVGVNKVLGATRSQLVVRFFVETATISLFAMILGVLLSVILIPLFNTIGSTNITIRQLLNWDMLGILAISWFVITLVAGSYPALFLSKIKSIALMNKGYNKQGKTVLVRQILVICQFTISIILIIGISVMLTQMNFIRNKDLGYQPEQVVSIPIRSFRSHEKLNTLNQQVQSLSNTLSTTFAQSIPGSNESGKTTYKLTTDKQGLPTLSCVTYGKTVNTLGLKLLAGTDLPDIWGRPDSTCYVLINEKVLKFLGYKSPGEAIGKHIVTEMSPTNSIITGVVQDFNYSNLKSEIGGYSYYTMNDPSESARNLLIRYKTTDVSGYIEQVKKIYMAIAPEAAFDFSFLDQHVQNQYENEIRSSNVMSLFSFLTLFIACLGLLGLAAYTTEARSKEIGIRKVLGASVPSIIHLLSSNYIKLIILSFLIAGPIAYYLFSNWLNDFVYHIEMPWWAYLIAIISVALVAFITIGFQTFKAALLNPVNSLRDE
>NZ_CP049333|1117571:1194056|1127459_1128077_+|WP_108635874.1|DBSCAN-SWA
MSQVTLNERGHKDAGLMQVAEQVLSKMAAETELFAAPVPALSILEEALVAFRNAATEAYYRDTRAILIRNQKRAELAYVLKELAKYVDTIANADPTIILAAGYAVRKSKTSYGGVVPKVERLIARPEEVGSGRVKLKTQRWRGARMYQYQFRIKGQNVDWSTQLCSKSSCIIDGLESFREYEFRVSYIGIDPTPNYSDIISSYVL
>NZ_CP049333|1117571:1194056|1118314_1118521_+|WP_165305672.1|DBSCAN-SWA
MKKITLKSIKNQEILSRDELKKITGGSDGSGAVGCAGKREWDSCTQSNGNIGKCQYLPFNSGLVCFRN
>NZ_CP049333|1117571:1194056|1187613_1187763_+|WP_165305682.1|DBSCAN-SWA
MNTLDLKGFGVQEMNAKEMMEIDGGQQTRVGKWLKAAGELAVWVAETFL
>NZ_CP049333|1117571:1194056|1118577_1120056_+|WP_165305673.1|DBSCAN-SWA
MKNAIRIQVILWSLICFVIVNVNAQNNLENIAESFGDSYFRFEVRDNANKKALSLKLTLTSNLTSYYDINIPIQGNLDTLLKIPSFKMTSAILKIDSIERYIFFFPNDTTKVIFKFDSNESSDIQYKGPYETIFRETKAIQNLFTNLFNGGISSNDYVFEPNAYRDRALISMKEKIDKIKNTTLSMDSKICLDRTFAAVYAKMFLLDPNNGMYIDNVDAGMDKERAKIKNRINLDYYTFLKDLDLNNKDYLLSNYYNELTKSLLADSVLDLPKTDQISSKDWMKTATTILAPLLGYSEGYFYNIMLANAYLDQIARGKLLSDRQSKDIVGYFNDKSFSDYLLYQNNINKIRITNDKGRVYDWSNLDKINILSEIIQKYPSKTVAIDFWATWCAPCLTAMDEIKPIKEKYTDVVFVYITDMSSSRTLWNNQVKNIAGDHFYLSSKQMEELQRQMNFSSIPTYLIYNTKGELMNQMTGFPGVKKFEEILRDTQK
>NZ_CP049333|1117571:1194056|1181632_1181770_+|WP_165305681.1|DBSCAN-SWA
MEKKLKEINVRELDEKEVVEIEGGTERENSKDVSWFESILNYFKP
>NZ_CP049333|1117571:1194056|1181152_1181476_-|WP_108635850.1|DBSCAN-SWA
MAKEEIGTIIRQKRESLKISQEAVAFILNMSQAAYSKIERNETKLKVEQVYKIADYFGITIYELLPPALASDITGENIFGLLFNYIMIAWKKTKKQFKKKNTDIHEA
>NZ_CP049333|1117571:1194056|1187190_1187523_+|WP_108635846.1|DBSCAN-SWA
MKLFQYIDRINLLDKLIRRRRTGTQSELAIRLGLSVSRLARIIEYLKDIGAPIAFDRSLNTYYYEKEYSIQIKVEVQQENIHLLDLNQMRQANAGDNFISIHLLNAFFVH
>NZ_CP049333|1117571:1194056|1188395_1188992_+|WP_108635844.1|protease|DBSCAN-SWA
MKQKIELLIFGTLQSSIILIVFFLLFGLDIASNTITMSDQFNIFLICICSAFFEEIIFRYYLIKGLGKSFSRKKSIVISSLLFAICHLANSNFTAIAFFSHFLGGIIYAYAYMQTKYIYYPIGLHFGWNYAQWLFSLPMSGTIKEGWFNLTFPTVNYWFGGAYGIEGGLASLIVRGLLLCLVVFTVSRYDKKSINDNL
>NZ_CP049333|1117571:1194056|1133037_1135431_-|WP_165305677.1|DBSCAN-SWA
MIKTYIKIAWRNLLKNKAFSAINILGLAIGMAGALLIALWLQNMLGMDRFHEKSDRLYIISNRDEFQGEKSAWAYTPKIMAPSMATDFPDIEAFTRYDEGNQFLTTFGDKKIIAKTVFVDPGFFNMFSLPLVKGSNNIQFDGPKGLVLTESYAKALFGDEEPIGKSVKIDSVNQVTVQAVLKDLPSNSSFKFDILLPFAYAKTIGYVDDNWGNNSISTYILLKKGSSLSDFNTKIRTYSRDHINTVNRAEGNQSAKYTGEIFAFPFKDSFLYNSGKGGNYTSGRIDIVRLFVWIGIFILLVASINFMNLSTARSERRAKEVGVRKVVGANKMGLIIQFLTESILISMIGMILATVLVFIVLPFFNELVGKQLNLSLLNLWTWLFLIGFAVFTGILAGIYPAFFLSSFQPIKTLKGKFISKTKGLSVRSILVVIQFSLAIVLIIATVVVTKQIQYTKQRERGYNENGLLYSSLKGDLEKNYKLLRDELLASNAVVSVSKNMSPVTDMYSNGWGFTSGTPTEEDKRISYNRFSTDADAVKNLGLTLIQGRDIDIYKFATDSTALILNESAVKSLHLKNPINSIVDGDGTKWTVVGVVKDFIMGSPFGDNKPMVILGPQAWFTTIHYRLNTNRGIAENLKTIESIFKKFNPDYPFEYQFIDKTYEQKFKETKAIGTLSMVFAGLTIFISCLGLLALIAYMAETRMKEIAVRKVLGASVAQVTSLLSVDFIKLVIIAILIASPIAWWAMDKWLQDYSYRIQIQWHYFAIAGLMAILISMATISYQAIKAALSNPVDSLRDE
>NZ_CP049333|1117571:1194056|1171672_1173034_+|WP_108635856.1|DBSCAN-SWA
MKKASILVVDDDQDLLTAARILLKPKVNHVQVESNPENLIGHLEKMPYDLVLLDMNFKSTINTGNEGLYWLSRIKEKFPQVHVIMITAYGAVDLAVKSLKQGAADFVVKPWENEQLLATIESVLAESKNREKKNKNSLLRSSNTPDLIGNSPVMDELQYKLEKIAPTDANILILGENGTGKDLIAQAIQRRSLRSDQVYVKVDVGALTETLFESELFGYKKGAFTDAREDRQGRFEAANGGTLFLDEIGNISLQQQAKLLTVLQNRQVTPLGSYQPIPVDIRLISATNVSLKHLADESRFRKDLIYRINTVEIQVPPLRERGEDIRLLAIHFLDIYAKKYNKRIEGFEPDAIKKLFAYHFPGNVRELQYSIERAVIMADQVSIAGNDLFFSPIEQQVEQVAVESVSSSQNLEELERKAIKSAIERYNGNISKAAKELGLTRAALYRRLEKYDI
>NZ_CP049333|1117571:1194056|1147724_1148015_-|WP_146191114.1|DBSCAN-SWA
MLKVIKKRVLAQYKKSYHAKSYKKTEFWRNIKKTYRAKSYKNNSLFVRKRTTYCPFSNNPTCAKNKIKHSYTTHYTYGKRIDLALCIATPDTNPPD
>NZ_CP049333|1117571:1194056|1190610_1191201_+|WP_165305684.1|DBSCAN-SWA
MSEIENYPGYVVEPRLINLYKANVVGFLFFAIFILLYGLPFYLLWDIKESFSIMKNNIYDKDSNVWWVYVIIIVSGIVIHELIHGIVFAFFAKEGFKSIKFGVLWKMLTPYAHCKEPLQVRAYMLALVMPFIIVGLLPGIYSIFTGNLPLLLFAIFFSGAASGDFMILNLIYKENKDNLVLDHPTEGGCFVLKKVM
>NZ_CP049333|1117571:1194056|1183659_1185822_+|WP_108635848.1|DBSCAN-SWA
MKKSPVCIKQHDIRDCGAACLASIAGYYGTHIPIAKIRQYCHTDTRGTNVLGMVQGLQQMGFNAKGVKGAMDAIPQIPLPAIAHVVLKEQLQHYVVIYQVEKDKITVMDPGLGKVEKYTFEAFQKIWTGVLILMEPNEYFEQKNEKTAVYKRFWNLIKPHRSVIVQALVGAAVYTLLGLSTSFYIEKITDYVLVDGNVRLLNLLSIGMLVILVFQLLIGTLKSVMVLQTGQRIDKYLILGYYKHLLSLPQRFFDTMKVGEIISRVNDAVKIRAFINDVAIQAVVNVLIVVFSFALMFTYFWKLALIMLLVIPFYLGVYWLSNKLNKKVERRMMEEGAELESHLVESLNSVKTIKQFGIETYFNSGTDNRFSHLLKTIYASVMNGLFSSTSGELLSRLFTIILLWAGSYYVIERTITPGELLSFYALIGYFTGPVTQLIGMNKTLQNALIAADRLFEIMDLEREESEEKLQLTSDLVGDIVFDNVRFSYGSRVEVFRNFSCRIEQGKMTAVIGESGSGKTTLGALIQKLYPLQEGKISIGQYDLNYISKSSLRERIAIVPQQIDLFSGNVISNIVVGEDIPNFQRLLQVVNELDMMSFIEKLPAGFETQLGENGSMLSGGQRQRIAIARALYRDPDILILDEATSALDTSTEQVIQRAFRRFKDSGKTMIVIAHRLSTIAEADTILVLKDGVLIEQGEHKQLLAQESVYKDMWKKQSIVLN
>NZ_CP049333|1117571:1194056|1157038_1159444_-|WP_108635863.1|DBSCAN-SWA
MSNVKLIFRQLWRHRLFTFLNVLGLAIGISACWFIFRIVNYEFSFDQQHPDKEQIYKVYSHTQQENESGDFDAVPFPLPYYLKENSQDVELVVPYYNRYFEVVTPASKSETPTEFSGQEKIFATTADYFKMVPYKWLAGSPHQLFKLQNEVVLTASRAKAYFPKLQNQDIIGKTISYDTTQFIVSGIVEDLSYPSTFIGKEFIKIPDQDPNLNNWMMLMNYYQLFVKVKSTDHLKNLAHTIDQKVLQMNGEEYKKENYKQTVRFSALSELHFNPIIQNHSNIKVLYGLIGIAAFLLVLAAINYINLSTAMVPMRARAIGIRKTLGEREIYLTRSFLTETFLIALFALFLSWPLTKMMELLFSDFIPPDLNNYNDQFNLLLFIIGLLVLITLFAGIYPSILINKVRLIDVMKIKSLSNNSNKGVFLRKGLIIFQFVIAQIFLIGTFVISIQIKHMLKSDLGFNQDAIVTISIPNRNADKATTDPFVFKQALAKYPEISRVSLGHFPMDNSYWGNPIRKYGEEESKNQFMQYKFVDQDYIDLYHIRLLAGRKLSMSDTSSGIVINEKAMKELGFKNADEAIGQAVVSRDKNVKIVGIIANFHSKDLHQQLNPIVMEVSTNRSPLGHINVRLDNDPKKWPTALANLEKEWKNIYPHAKFSYRFYDQEIKSLYETDMRLSKIINLATAITLLLSCLGLVGLVTITTVQRTKEIGIRKVLGSSVTGIIGLLSKDYIKLIIISILVSTPIAWWAMNEWLRDIPFKIEIQWWLFFIPAILTIMIAFMTLSFQSLRAARANPVDSLRDE
>NZ_CP049333|1117571:1194056|1145270_1147679_-|WP_108635867.1|DBSCAN-SWA
MIANSLKTAYRFLKKHKLITFINITSLAIGITATLVIFLMIQYDYSFDKHVSNQKQVYRVVSNGEFKNAGVYVPLVRTMQAELPNLEAVAPIYRSHVQKLKVSLATDKFQVFPKEQQIVFTNSQYFDIFPYKWLAGNAQTLNTAGHIVLTKKALEKFYGKESPSDVIGRTVIYADSIPLQVAGVIENPQHNSDFNFDSFIAESTIPQNNSLKDMYSWDAWNSISDTHQVLIKTKAQPNPHLLERNIANLLQKYKYKEGEKINDKLELQALADVHFDTRFNYDATHPGTLRNLILLAFFLLALGAVNFINLSTAQSIERAKEVGIRKTLGSSKATLIKQFLLETFLITLSATILAVLLLPLFLHVFEGFIPKNLNLDRLDKTVIAFFLFGQLILVTLLAGFYPAWVLTGYAPVLALKNQLGKNTNLSRSSWLRKALTIFQFVMAQAFLICVLIVVRQINYVTHKDMGFQKDAIVNIYIPGAFQNSAKGVILKNELKKLTDIKAISFGNIAPAMNGWMTTAIAYDQSPNKESLTFDGRSGDENYLDVYKIPLIAGRNVRLRDSTSEMLINRKGLELLHIKNPQDAIGKTFENGQNIIVGVMEDFDLASARQGVKPVLYTGSKTGYVLHIALDQSHPENWKNTIDKITLSYKSVFPDDELDLRFLNEVIQNFYTQEKQLSKLLSWAVGLSVFIAGLGLFGLAIFTANQRTKEIGIRKVLGASVFQITFLLLRNLLSLVAIACLVAFPIAYYFMHNWLNDFVYRTTINPWIFGFSALSLIAFASVVLSAKSIMAAKANPVNSLRDE
>NZ_CP049333|1117571:1194056|1117571_1117769_+|WP_165309558.1|transposase|DBSCAN-SWA
MINDVPPENNASERAIRNIKVKQKISGMFKSAKGAQNYAIIHSITDTCNKNQQNILNAFRTIEAT
>NZ_CP049333|1117571:1194056|1135461_1137846_-|WP_165305678.1|DBSCAN-SWA
MIKTYIKIAWRNLLKNKAFSAINILGLAIGMAGALLIALWLQNMLGMDRFHEKSDRLYVISNRDIYQGELQAWTNTPKIMGPTLKSDFPEIESFTRIEQDDKFLTSYGDKNLVSSASFVDPGFFNMFSYPLLKGNKTNLLKDANSVVITEQYAKALFGDHDPIGKTIKIESKYLVTVQAIVKDPSSYSSIQFDYLLSWDLAKKMGFVDENWSNNSTYTYVLLREGVTLENLNSKIRLFSQNHINVGDNEIKSTNEIFAFPYKDTYLYNKSENGAYTAGRIQLVHLFTWIGAFILLVACINFMNLSTARSERRAKEVGVRKVVGAQRKSLILQFIVESILISIGATILALVAIVLVLPAFNNLVEKNLTISILSVNTWLFLIGFTFLTGVLAGSYPAFFLSSFKPLKTLKGKLNTYNKGLSVRSILVVVQFSLAIILVIATVIVSQQIQHTKDRDRGYNDNGLAATRFTGKLNNGKIYQTLRNELLASNAVISVSKNMSPVTDRYSNGWGFSWQGSTESDKKISFDRFSTDAGAVKTLGFKLVAGRDIDIYKYPTDSNAMLLTETAVKQMRLQHPIGQTINGDGQDWVVVGVIKDFITESPFAASYPMVVFGPKSFFTNIHYRLNPNNSTAANLKTIEAIFKKFNPEYPFEYNFIDENFEAKFKETQSIGTISMLFSGLTIFISCLGLLALIAYMAETRMKEIAVRKVLGASVAQVTSLLSVDFIKLVIIAILIASPIAWWAMDKWLQDYSYRIQIQWHYFVIAGLMAILISMATISYQAIKAALSNPVDSLRDE
>NZ_CP049333|1117571:1194056|1193387_1194056_+|WP_108635840.1|protease|DBSCAN-SWA
MLTKDKIKLVGYLYLLFMGIGMVLMLIIKSVDTFLVVDYYKLPSLLNHDVFRSIRALAHNNSFYIILLAAFFAPLVEETMFRLWLSFDPRHIAISLSVILIYSLLGFKNLFKMNLMTLAIVSSFLLICLLTYQILKGMNIEQFLMRIVSIKVLGSISAISFGLVHIANFAPINTSIWFLYPIYVLPQIILGYLTVFLRVRYGFIYGVVLHVLVNFVAVLVKI
>NZ_CP049333|1117571:1194056|1162784_1165151_-|WP_108635861.1|DBSCAN-SWA
MIKNFIKTAFRNLWKTKGYSFLNIFGLAIGIAAAALIFLWVENQLSYNDNFPNKKDIYIVKSKQTYDGATFVFESTPGPLAQNIAKEIPGIKHAVRMTWINPMLFSVGDNNLFQNGLYADASVADLLSLEFTEGDRKTAFDKVDNIILSESGAKKLFGNQPALGKTVKTNNKDLYIVSAITKDLPKNSSYEFQWLIPFKKFESTQDWLTRWDNNGIQTLIQVEDNANVDQINKQLMNYVKNRTNGEVTFSQNFLYPMERWITHNRFDNSGNEIEGSLKNIRLFTIIAWIVLLIACINFMNLATARSEKRAKEVGMRKVVGASRQSLIGQFLAESLVLASISSLVAILLVYICIRPFNTMIGQDLQVDLLKPMHLAFVITITLICGLFAGSYPAFFLSAFKPLSTIKGAKQKAGTGSLIRKGLVVLQYTASVVLIICTIIIYQQIQHNKNKDLGFDKSQVLTTALQGDMAKHLPLIKNQLIATGLVEQVGVSDVSILNIYNNTSGFNWEGKDPNKSILIGMLRADEGLVPALDLKMFDGRNFHANLLGDSTSVLINETLAKLIRKDGHVVGSILNYGEENYTIAGVVKNFVYNNVYADPDPMLFIPLVRESGLLNIRTKAGIDLPQAIQQIEKIIVKNNPGFPFDYKFLDETFNSKFQAELFIQQLSSVFAIISIIISCLGLFGLAAFATEQRAKEISIRKVLGASVSGLIQMLNREFIILIGISCIIAFPIAWIFMHKWLADYAHHITISWTVFVLSGLAAIVIALLTISSQAFKAAIANPTKTLRDE
>NZ_CP049333|1117571:1194056|1169221_1170082_+|WP_165305680.1|DBSCAN-SWA
MIKKVCFFLLLLCSAFLASAQFNNTNSLLWEIKKKGNVESSYFVLVTGDLCDIPQSLLDRILGLRSNIHTYYMESALSNKKSDSRSAEVMFLKKKEPSIRGFLTDKEYDRLRERMREMNIDEKTLNKMTPVFIENLLKRKAAGDCNKTNVIAKTFSEYAGQYGIEVKELVDFEHSVANLLGVPNEWRVERIKYFLANETELKADLAKKAACYEQEDTKGIIDLYSLSRFLRPSETDMLRAKELCPLIEAADKGGVLFTVDLINLADNKNNLFDLLQQRGYQMSPIN
>NZ_CP049333|1117571:1194056|1121698_1124095_-|WP_108635876.1|DBSCAN-SWA
MIKNHLKTAWRTLTHNRIYSLSNLVGLTIALFVFMLISSLVVDELSYDRQWSNSNELYRMRIVPKETKEGVTNNISGAPEGISATLKANFPEVLGYTSINSFSPKLTINKRSKRLAEINTLEIDSGFFNLFDAKIIAGNPKQVIAGAKNITLTASAVQKHFGGKDVLGSTFYNKPQEGEPEAYYVNAIIEDMPHNSSFQAEALVLMPKVNEFNPAETGSLQTQLLLLKSTTDINSFSTKINKWYNAQKLNDWAKGHNLIIEPIKDIHLLSITGWENPMQDIYLLAGIALLILVLVSINYINLSFAHALKRAQQIGIRKVLGASRKNLIMQMGLESTILFAGSFLIAFFGYVLISPAFEHYLEHPLTMSYQHSLLMFVGLLSTWILLGWLCSLPTALSLSKTQPSLELRRQLSFFRLPLNMAFTKVLVVIQFAIAIVVAICMMSMRAQLNYLYSKDLGYEPKNLLAINYTSWEGKDQAFKQELLKNSYISSVSLTGWTPFSGSVDFKTVKDPDNPNEDLAVVFVYADYDYIKTMGIKLLDGRPLSADYAMDRPFTDSVHNGQPVFTNMLISEGTAQRLSLKLNRSNEPLKNTPVGVFKEFNGASLKFPIGPFAIKAQKEWEGGCMLIRVEEGKKKEALALVNSTWNKFFPNRIAQINWQEDQVQHQYNKEKKQYQQLALFTGASMLIAILGIVAIAIYTLERRVKEIGIRKVLGASVNTITYMISRSFIVLLLIAILIAFPTAWWFTHKWLENFYYHIDVPIALFVFTGLFIGLTTLAIIAVRIFRTARINPVNSLRDE
>NZ_CP049333|1117571:1194056|1185838_1187185_+|WP_108635847.1|DBSCAN-SWA
MMNIYRRESIKYCLILIWVMLSVDVLAQQTWTLQDCIDYAVEHNLPIKQQEIKAAIKVLDQEMALRERLPSVNGYANGYTTFGSSQDVFGTIRRNDNLNSNMGINAELTLYQYNYFRNQAKKAASEAEQERIEKEILKRNLTVQLMEAYLQTLLAQALLVSQDSAMQFSKQLLDKAEKSTAVGATAVSVVAEAKANLARERQQYQQYHKDRQQSLLKLAQLMNHPDYSSLRLAVPITAQDPQHDSTFSEISNLREEAYLHNPVFAKLQNQKDGLDLESKLIKAALFPTVKGSAGLGSTYFNAFKAENTRSFFVQSKDNFAQQLAVTVSVPIFNKGKTKRQLKQIEFNKQNIQLSADNERLAQQHILDKLLLELDENRKQYGIAVEASTATEQSLDYTLRSFEAGKASIYDINTSKSNLIKAESEKIRSKYNVVFNQLLLRYQIYGTIN
>NZ_CP049333|1117571:1194056|1182521_1183622_+|WP_108636102.1|DBSCAN-SWA
MKRTNIIYLLLIAAIVIGLILLPLIKVPISISAQGIIRPKMENAKILSLVSGRIIDNRIVGNNQQVKEGDTLLIVVSEDLENKLSLNKDLMADYSRQIADLKLILAGDAKNVQGGQYQLEYLSMEQRMSEIQSQLTLARRELERNNKLYSQGVVSQAELDKTKYSFEQLENQFLTIRKQQMAQWSAKLVELQQKAQSLSSEKKSILIDGQNYIVRAPITGTVVNFKGYQKGGQLVQGQDILEISPEDQLIAECMVPTKSIGYIKNGQSVKFQMDTYNYNQWGFLSGTVHDIDYNLVTDQQQGSFFRVRCRMDQNFLGLPNGNKVFVGKGNTFNARFYLLDRTLWQLLFDRADDLFNPNLGAKTSAL
>NZ_CP049333|1117571:1194056|1162000_1162684_-|WP_104385115.1|DBSCAN-SWA
MIKITNLQKYYRTEEVETVALNNLNIHVKEGEFVAVMGPSGCGKSTLLNIIGLLDDLDEGSYLFNEIEVAKFKERGRSDLRKHNIGFVFQSFNLIDELTVFENVELPLVYTNVPAAERKKRVEEVLEKVQIMHRRNHFPQQLSGGQQQRVAVARAVVNNPKLILADEPTGNLDSNNGNEVMQLLTELNEAGTTIVMVTHSEHDAKFSDRVIRMLDGQVIMETTSLGS
>NZ_CP049333|1117571:1194056|1137865_1140220_-|WP_165305679.1|DBSCAN-SWA
MIKNYLKIAWRNLWKSKGYSAINIIGLSIGMAAVLIIGIWVQNQLQFDNFYSNKDRLYKLWNKYQNDEGKISLMDVTSGRAAPALLEDYPEVERAARMYFSTNRLLSFDDKKIKSKGNEVDPSFLQLFDFKLRRGNNHQALAETKNIILTESLAKSIFGNIDPLDKTITLDNKEPYKVSAVMQDLPSNTNFDFNYLIPLADASKYSPNWNTITFSTYVQLKSGTNIEAFNNKLINIIEKKSNKELKGSLFLYPMSKMHLYSRFEQGIPVGGKIDQVKLVAGIGLLILLIACINFINLSTARSQKRAKEVAVRKVVGARRLNLIVQFLTESVLLAFISGLSAIVLTKLTLPLFNKILDRPLTFSFSDTTIWLSLIGFILITGLLAGLYPAFVLSAFKPIKSLKIFARSKKFSLSFRELLVVFQFSIAVILIIATIVVRRQIEYAGQRDIGYNTAQLLEIGMEGDLGKNYEAIRSELINNGVATAVTRIGLSITGSSGNSWGGFSWAGATPEQEKKMGFDLGRAESDFVKTLGLKLIAGRDIDYARLAADSTAALLNEAAVKEMKLENPIGSYLKWGDRNYTIVGVINDYISGSPYNPVKPMLIYANKTALFNLVIRTNPNASMSDQLKKIEQIIKKFNPAYPFEYQFVDQKFATKFKDQQQTAQLAFIFSGLAIFISCLGLFGLASYIAELRTKEIGIRKVLGASVSGITAMLSKDFVKLVIISILIASPIAWWAMNKWLQDFSYRIEIQWWIFALAGLAVAFVTVSSQAIRAANHNPVNTLRDE
>NZ_CP049333|1117571:1194056|1165186_1167562_-|WP_108635860.1|DBSCAN-SWA
MIKNAIKTGIRSLLTNKKFTLLNIAGLSISLAVVIIIALWITDELSFNKVFNNSNRVYELSANFDKENDQFVHAGPPPIAIYGKSKIPAIEEICRISGGRNIQFNKNELMTSEYGVYVDSTFNKVFDSSIKLLEPNKLFQGKQSIVITEKIANKYFKNENPLGKTLYLEVDPILKTGKQPFLITAVVNNFPSNSSLKADYLLPFELLNSLSKEPLDEKWGNFQYYIYFLLKQDSKSAQVAEQLTAIQKSNFQGNPLYSKFAFFLQKITQLNLYTPKGDNNGIQSIYIFAIIAFVILLVACINYVNLVTARATKRTKEISIRKIIGANRSHLFLQYLIESAVLFLISLFIATAIAYLSIPFFNTIAEKNIQFSLLSSELWYIFLLTFIATVFIAGIYPAVLFSSSKLLSQLKNNNTLFGNKNNLRKGLVVLQFCCTVILIVTTFIFEKQLRYMRNKDLGYDKENVFLFEQKNFLTHYEAVRNELQKQQGILGVTAASNDISNIGSETADIDWNGKNRMQSNFFISRVAIAPNFTSVLDIKLTEGNGFKNNPSDSSHALLNETAVKQMGLKNPIGQTITFQGKQLTIVGIMKDFNFNDLKTAIKPCIFFSGMGYALGGMYVKTSPGQEKQALSAVQKLWNKYNPESAFNYSFMDESFDKMYKKDVVHGKLVQLFAAITILLSCIGLSGLVLFSTEAKLKEIGIRKTLGASKQDIVMMIGKDYMVPVILSFLIAFPISWLIISNWLNNFVYRTSIDPWIFLLASLITILLVVLTAGSVSLKAAMINPTKILRDE
>NZ_CP049333|1117571:1194056|1154614_1156990_-|WP_108635864.1|DBSCAN-SWA
MIKNYLITAIRELRKRKFYTAINILGLSVSLTASILIILWVQDEQSFDKFHPDYEHIYKVNSHLDPEHNGSIWENSPGPIGNYAQNIPEVDYATRISQDHNTTLVNDKLKRPVTDMNIYYVDSNFFNMFHFPLQEGSLSGFQANYKQALITPSTAEKLFSTQQAIGKTFRYQKDLFTVAGILKDLPQNSSIQFDVVIPLGYHAQRFTNWGGNGKWKTIDEDMGNYSFSTYVKVKPNTSAALIGKSITDSYTKARNGENSTVFVLDPLKTMHLIAPDGNKSTLRMVQIFGIIAVLLLVIGAVNYVNLSTARALDRAKDVGIRKIIGANRLHLFLQFITETIVVFLCSLLIAFILIFILHTGYNQIAQKSISFSFRNTAIWLYIGIAIIGTLGLSSIYPAIQLSSFNPIHSLKGKSVKGVSSNTMRKILVVFQFTLSVTLIVCTLVIRNQLAFIQKINLGYDRDHVMTLGLPEEAYKHMDAIRTELKNNNAIQAVSLSGVYNMTDFGNATGDIDWPGKSKDNKLIVAQATIDKNFIPLMGIQFLEGENFTGMPADSSGYVINETLAKQMGLKPPYVGSNMSFHDVPGQIIGVVKDFHFKSIKDRIGPMVFWTRYGAGTLYVKTSTTKAPEAIKALEKIYNRYPSDAPFNYTFIDQQFDNLYKSERRTGLLFNIFAGIAIFISALGLFALATHEAQMRIKEIGIRKVLGASTFGVVRLLGKNFVILVSIAILIACPIAVYLMKQWLSNFAYKTDLDVQTFVLGSILALLIAIITVSYQAVRAALSNPVDSLRDE
>NZ_CP049333|1117571:1194056|1130600_1133006_-|WP_165305676.1|DBSCAN-SWA
MIKNNLKIAWRNLRRNSSTSIINITGLALGIAICLLISLYVADEFSFDRFNTNADRIVRVVFRGTVKGGTMNEAHVMPPVAATMKAELTEVQETARLRQGGAPLFLVGDKIFRDEQMAYVDASFFKIFTLPLIKGDANTAVKMPYTAVISESMARKYFGTTDVVGRDLTIKGDQNRLKITGVMKDIPSNSHFHFDIFTSMTALEDSRSNSWMTSEYYTYALLAENTSLKNLEKNLATLFDKHVGAQFMAGFGMSYEDYKKSGNTIGLYLQPLTDIHLHSNFGYDLSPSGDIRYIYIFSAIALFMLLIATINFMNLSTASGFRRSREVGVRKVLGADRQSLIRQFLFEGILLTYLALFLAVGIVLLALPLFNQLSGKSIAIQQLDFARIIPLLLAFGLLVGLFSSTYSALYLAAFNPLTVLKGRLLRSTKRFNLRSSLVVFQFMISVGLIFCTVVVIRQLDYMRNIKLGYEKENVIVIQSWPLGKNEKTYVKLLSEDSRVKHISRSSYLPAGETNNNNFFVYPDGNTEKWVKTLRYDIDEEYIAAMGMQLNEGRNFSKAFGNDTLSIIVNETAAKDLGWKGKSLGHTLTNKDNKTYRVVGVVKDFHFKSLHEPISPLVMVLSDQAGSLIVKTQTKDTEALIKKLKAVYDSFPSDIPFNYSFLDDRYAQTYQAEVKTGKLLSIFAGLTIFVACLGLFGLAIFTANQRRKEIGIRKVIGASVPGITGMLSAEFIKLVLIAIVISSPIAWWAMYKWLENFAYRIEMQWWMFAVAGLIAVLIALLTVSLQAIKAAVANPVDSLREE
>NZ_CP049333|1117571:1194056|1179092_1179638_+|WP_104384853.1|DBSCAN-SWA
MADQGLKWYVVRAVSGKEKKVKQYIDAEVSRLGIEHLVPQVLIPMEKYYLMRDGKKVAKERNYYPGYVLLEAALDGELEHVIKNINSVIGFLGDKAGNAVPLRQAEVNRILGKVDEMAEQGETINVPYYVGETVKVNDGPFNGFTGEIEEVHEDKKKLIVMVKVFGRKTPLELNYMQVEKE
>NZ_CP049333|1117571:1194056|1142835_1145217_-|WP_108635868.1|DBSCAN-SWA
MIKNFIKTAWRSIFSNKFYSAINILGLTAGLVVGIFLLLWIQDELSYDRFHKHHRSIYKIGIEGGTGISKRISGSIIAPVGSSAKKEIPEVQDAVRIFKIGDAALKYKEKRFNEKNLAFVDPSYFSVFDFSLMQGDPKRPFPDNNSVVITQSTAHRYFGNENPIGKTVILGIEDLCVVSGVIADYPENSTFQFQVLLPISRFNEHAYIKNKTTYDNKTFLSSMDEDWSNFSFETYLQLRPDANPATIAQKLQSIHERNKPEDAPVPYVTQALAKVHLYQMDGSDGGIGTVRIFIGVAIMILVIASINYINLSTARSLSRAKEVGIRKIIGAGKKELFFQFILETTLLFTIASTLALAIVFSCLPLFNNFSGKHISLQLSNPTLWTSILTMLIGTLLLTSIYPALLLSKFDPIKVLKGRFALKNSSARKILVVLQFTVSIILITLTIVIGRQLDYIKHQNLGYEKDHIISIGMAPKMSKHFDAVKSELLKNKDIDAVIRLGRDMVYGGGSTGDNDWDGKPSKSNLWFNITYSDQSALSFFQIKLTQGRNFTGSTADSTHFIVNETAVREMGLKDPIGTRLRIRTVPGTIIGVVKDFNYASARQKIEPMVFQYSPKDCWQLYIKTTASGAKSALNSMQQIWKNYYDDMPMNYSFLDESYQKQYTNEQKQGTLFNFFALIAILISCLGLLGLCTYTAQVKTKEIGIRKVLGATVFNIIKLLNKEFLVLVILANVIAIPIALYFSINWLNGFAFRTTLPMTIFLYAGGITIAIALFTVSFQSIKAAYANPVKSLHDE
>NZ_CP049333|1117571:1194056|1177435_1178620_+|WP_077437774.1|DBSCAN-SWA
MAKEKFDRSKPHLNIGTIGHVDHGKTTTTAAITKVLADKGLSEARSFDSIDSAPEEKERGITINTAHVEYSTANRHYAHVDCPGHADYVKNMVTGAAQMDGAIIVVAATDGPMPQTREHILLARQVGVPALVVFMNKTDLVDDPELLDLVEMEVRELLSFYEFPGDDIPVIKGSALGALNGEPEWVEKIMELMDAVDNYIPIPPRLTDLPFLMPIEDVFSITGRGTVATGRIERGVINSGDPVEILGMGAENLKSTVTGVEMFRKILDYGEAGDNVGLLLRGIEKTDIKRGMVICKPGSVTPHDHFKAEVYVLSKAEGGRHTPFFNKYRPQFYFRTTDVTGEISLPEGTEMVMPGDNVTISVKLISPIAMEKGLRFAIREGGRTVGAGQVTEII
>NZ_CP049333|1117571:1194056|1180734_1181151_+|WP_108635851.1|DBSCAN-SWA
MLKSQKNRPYYIVWEDGKCHAMEPSYTTYRYDLHFATGNTIQLADDEAGRLMSQYYFYDSFFVDLIQVEALVPFRFNLNVPERFLYLFFMLEGECSYGGIDKIISVTANSVTLEHVNHKIPIGPIYAEAFLAHIAFFG
>NZ_CP049333|1117571:1194056|1124122_1126528_-|WP_108635875.1|DBSCAN-SWA
MTFTNFKIAWRNIRKKKIQNLINLIGLTLGITFLLLVGAYMWDVHRVNSKIKNIDQQFLLQSKYKKEGFGINLTTIGALPKALYEDYPDLVANYYRIDGLTGIIANGATIHEEGMALGDPSLLTMFGFELLAGNPKTALNNPFSVVITDRAALKYFGNINVLGKTLQIKNFKGEKHDFEITAIIKTTVQNAVMDLTKDMHSDIFLPIANEQYFGRSVDNWNNPYIAGYLELKAGVTTQQLDAAIQTLVHKNTDQEFASQYSPDLKPLKSYYLDDNQGAVRKMIQTLIWIAIFILVMAIINFINFSIAQHITRLKEIGVRKIMGSSRLQLVRQLLTEYILIVAIAALISLPMYCMVHPLFAHVLMRELPSLINLPGYFFGLLGLLTIVVGMLAGLYPAIKLSNIKILPSVKNQFSALGDKQLIRKVLLFFQFAVALLLLVCTLIISKQVNLFINSNLGYNKDYLLTVQAPRDWSENGIRKMETIRHELLQESAVKSVSLSYETPGLLGFNMQPAFGNNNDTDVQVQRITSDGYFLETYEIPLLAGTFLPKNAVTGTTNRPVVINKKAMEDFGFSDAQSTIGQQIALNDPKDKMTIVGVTDNFVANSLHQASPAIAWTDIRESFQYRYLSIRLKPGQLSSAVQGLEKKWKQLMPDAPFKYQFMDDRIKGLYETELQLHRAAQIASAVSLLIVVLGLTGLISLSIHLRNKEVGIRKVLGASLAHLMLLFSKEYYGIFLLAILVTVPSSYMLMQHWLQNYIIRIEINAFTYLLPLGILLSMLGLLVGFIVFRATRFNPVEKLRDE
>NZ_CP049333|1117571:1194056|1159478_1161896_-|WP_108635862.1|DBSCAN-SWA
MKGLKLILRQWGRNRLFTFLNIIGLAIGISASWIVFRIVNYEFSFNQNHPGKERIYKLYSAFKEGENIHRFDGTPYPLGTYLGNNLKKDLTGLELVAPIANRSFESIKVKRSNNETLEFNEQDQIISATADYFKLVPYKWIVGNPNTALKNNNEIILTASRAKQYFPDADLKSLLGKTMQYDDQLLTVTGVVADLDYPSSFISKEFIRVNPNPQEAENWENSSSNFHVYVKLTETGSPAQVIGAATKKFNEMVGEKFKQYNITAGYELAPLTELHFNKFVLNSSDKQVMYGLIGIAAFLLILASINYINLTTARVPARAREIGIRKTLGEQPRHLTLSFIKETFFTCLFGLLFSWPLVKIFELTFSSYLPQNINAYSDGLSVFIFLLGLIILLTLISSLYPAYLINKVHVVEAIKIHATDKISFGGISLRKILIVFQFVIAQAFVVLTVIMGLQLQHALHSDVGFQDDAVITLKLPYKKAEDSGKSPFLLKELLQKYPEIDQVSLGHLPMNNDQWGNNIMMQSDTGQILVNMPFKYIEENYLDVFQMKLLAGRPLKLSDTTSGILINQKAISKFGFKTPVEALGKTVTVNDRPTTIVGILADFHNFNLHAPLEPLAMQISTNKGTLQNINIKLNGDPKKWHQAIASIKTEWENVYPNAPFAYQFYDQRIKELYEKDYRFYKIINLSTSITILLSCLGLIGLVTLTTHQRTKEIGIRKILGSTISGIVLLLSKDYIKLIIISILIATPIAWLAIDKWLTDFAFKIELSWWMFIVPAIVTIGVAFLAMSYQSISAARANPVDSLRDE
>NZ_CP049333|1117571:1194056|1120527_1120752_-|WP_165305674.1|DBSCAN-SWA
MTKLGEFLAKKSVNKSQIARKTGLSKARINELTMTETAKLRLDEMYLIALAIDTDPAKMMLELCGHLELKEIEE
>NZ_CP049333|1117571:1194056|1167645_1168899_-|WP_108635859.1|DBSCAN-SWA
MDRPLEKKKWNSKRILTIVGVAGIVGLIGASFYFTSGKSKLNVEADRISIVEIKNGNFQEFIPINGTVLPISSIYLDASVGGRVEEKFVEDGTVLKKGDPIMRLSNTDQELTLVQQETQVLNLLTQSQIAQTNAQQASINNRNQMADVEQAYREAERVYNLNKKLLAEKAIGTQEFEKSKNEYNYQKERVHLTKQILKQDEISNAQKTNQDKQTYQRTQSALELMKRKIGDLIVRAPVDGQLTAFDAEIGQNKNAGERLGQIDVLTGFKVRADIDEHYINRIFPDLQGEFSIGDKTYKLRIKKVYTQVTNGRFQVDMEFINDVPKGIRRGQTLQIRLALSDETKALLLAKGGFYQQTGGNWIFKLDKNGGTAYRVDIQLGRQNPEYYEVIKGLQPGDKVVVSSYETYDKVQELSIKR
>NZ_CP049333|1117571:1194056|1120876_1121560_+|WP_165305675.1|DBSCAN-SWA
MSDKFKPSTKVYKRKCQEIEILIFYRMILHRISRHLSPEEVSFLMGKPLDFMTKIETFRIKQISMHDVFVMNDVLAINNLDTMVHMGVKISSAEKRYELHMTKLADRVIYRLYKVDEEQDQRVIEFKLIDIRHDIDPYESSTADEVEKIAAFLEETIDAGYFNEEKQPDEVHKLCCEKLESYVRPKNLMKVLNDLLSLSGERKIVQKESPYGFAYVLAAHTESTEKK
>NZ_CP049333|1117571:1194056|1128165_1130550_-|WP_108635873.1|DBSCAN-SWA
MIKTYFRSALRQLLKHSYYTFLTIAGLGLAIACSLFIYSYNSFQYSFDQFHTDKELTFLVVQDLKLEQVEHSKGGSYAMYNAISREIPQVERTALYMDNKDLTLRIADQLYKTEGKAAFVSSEYFNTLNFPWLAGSPKDLDQPNTVALTKTMAKTYFNNDNPLGKTILVDSKFPVKVVGIIDDRNKNSDFRSEIYFSQSSVSTLWQIPQNDGFFNNWGYSNSSNNILVTLKNAADKNTVEQAIHALVAKYWHKDVLQTFSYKLLPLTSYHFDTDYGKGTQRTLLSILVAIAIGVSIMALVNYSNITFARQMNRSVEMGVRKVLGCSKRQLYIQFLIETLILTAAAIIFALVLLLIFSNWANQALFPHEPVQIVHPRSFIAIIGIIWVLTSLLTSIYPLIFVNKMDIQQALKKLTIGPWNFSRKTLIVFQNMIAMTLLIATFVIVLQVNHLKNTDIGFSREQVILLPFTKKMIQSKAKIAHFISNRTDVQSYTFSDNPPSSEKVWGGTIQFDNRTEWEKWPARYAIGDSAYISTFNIKLLAGKNFNDNPQKPEFLINQNMATALGYKDPNDIIGKSLNAGGLNEEQVGTIVGVVADFSTNSLNEPISPTVIGYNETRLKNVAIKLKGTDHQLLVKDLEQQWKNWYPDEVFQYKFYDQQIAQLYKKEVLLEKLIWIAVIVAISISMLGFLGLLSINILKRTKEIGIRKVLGSSVTGIIVLLSQDFFKWITIAFLLATPLAYYLMNRWLDNFPFRISMGWWIFASAFCVGLMLTIAVVSLQAIKAATSNPVDSLRDE
>NZ_CP049333|1117571:1194056|1178877_1179072_+|WP_028072657.1|DBSCAN-SWA
MAKVLDFFKDSYVEITEKVTWPTWSQLQSSAVIVLVASLLIALVVFVMDKASSVGLEFLYGIAS
>NZ_CP049333|1117571:1194056|1174624_1175152_+|WP_108635854.1|DBSCAN-SWA
MNYHLKYWRHYFISHSRHGTHSPFVYKLVDEVIYQQDDPDRILNLPREVSMGGKVEIKKYLLVDRLLKTFAYDQFMFLTDEPPASYEELFKQKAGSYSFRKIYYIDQTNLDLDFLAVVGERDMLIVNEPHLSVEREEYWNKLRDDDRVVVTIDLYRIGLVFFRAGQRKENFLIRF
>NZ_CP049333|1117571:1194056|1170258_1171641_+|WP_146191113.1|DBSCAN-SWA
MKRIYIYSTLCFLLAYAKVDAQQSEQGIEEKAVFNKESTVNSENQRPKRSLTECIQLAIKANPTLLQNELAVKRAEVNLSQAKANRLPDLNGRLGHSLTSGRSVDNSTNQYITRNNSSGNFSLDASVPVFNGFRILNDIRMRADAKTAGKLEFDSQVNALKLDVITAYIQVLTAQDVLKQSELQTEVTREQVRRAEAMQREGAINPGDYYDLKGQLANDINSIENNKQILYMNRVKMAGFLNIDEAQLGDLQALELTTDAQKVDATTLYKLATENLPDIPALDWKIKAAEKNIKIAQSSYWPSLSLSGGLNSNYSKNGMEGDYWYQMKNNVGKYVSLNLSIPVFNRFKVRNDVKLAKLDLESTKFQREIALNNLRAETSNAVFNLKNASNNIVQLHEQNTNFAESFRIAKVVFELGNSNSVIFLTAKTKYDNSQIQLVVKQYEWLLQKYINDYYAGSLNL
>NZ_CP049333|1117571:1194056|1140435_1142802_-|WP_108635869.1|DBSCAN-SWA
MIRLFLKTALRNLKRNPLNTAINILGLSLGITVALVSTLWISKQFSFNKHYENHDSIYQMMMTGTFNGEKSTDGTSTPIPLAKVIASDFTDEIQDLALVTDMESNTIKVGDKKLNASGFYAMGKFSELFSFESVLGNTLTPTATSSIIISESLANALMGSADVIGKTIQLNGKEQYTIQGVYKDIPENNTFHGLQYILPFVDYLRKNEGIDEKWSNCFFSTFGRIENPQNIPGIEHKLTSIFRTNLTDINPEILLHPMSKWHLYDAFKNGKNVGGQIQYVWMFAWISVFILLLASINFINLSTARSLKRGKEIGILKSVGVNRRQLITGFLVESILSVSCAFLIALIISTLLLPWINAITKTTLAIPFTSIQFYLYSFLGIFSVGILAGIYPALFLSSFNPILALKGKMNIGKRGFNARKGMVVVQFAISIFLMIATYLVIKQLHYTKDRPIGYKSSNLVNVTSSSQLISKNFEILRKELIDQGLIQEASLTSSFVNKLTLTGGGFNWQGNETKEGSIMGIFTVDENFANTVQWNFLKGRNFSKDFKTDSTGVIINEAAAKFMGVTDLTSKQLSKRGINYTIIGIIQNTLSESPFKSITPTAYFLDFLPKNKITLRLNEQQDISQTMKAIAQQFNRFDPDLIFDYAFTDKEYAKQFEQMEMIKSLTSIFTGLAILISCLGLYALVAFLTEQREKEIGIRKVLGASELGLWRLLCTEYIWLTLIGFLVAAPLAYLLMESWLENYVYRISITWTVFAVTGLTALVITLLTVSYQAIKATWANPVKTLRSE
>NZ_CP049333|1117571:1194056|1192569_1193043_+|WP_108635841.1|protease|DBSCAN-SWA
MSDIFKVIAIPKHRNLYFFLVFFLIEEMTNWGAYYLFDHFSPGFADIEEYHKQGLTFTFVLLVIVAPILETFFAQFFILEVLRKLKVSASISVVIAAIVFGLFHYYNIWYILATIISGFVFAYYYMALRPQGKWNKILLLIALHAMANIVAFFSTYA
>NZ_CP049333|1117571:1194056|1151986_1154404_-|WP_108635865.1|DBSCAN-SWA
MIQNYIKIAWRNILKNRGYATINIIGLAIGLSCCLLIVIYVQHELSYDKYHLNKDRIYRVVHDYKEVGSTSQQQIWGNAPIGEALKADFPEIDKIVQFSGQTSILLKKGENRFQEENVFFMDSTAFDVFSWKVLAGNPHTALKNAYSVVLTESTAKKYFGDQNPIGKTIEGGLAAGRADAGLYTVTAVMADVPANSHFTFDALLSMSTFRKARPDVFEKEGWGYVDFYTYFLASKDFDPVKFNQKIPDFLKRHIPVQENANSRYNFHLEPMLQAYMHSTADRQPGATGSYQNLYIFTIIGGFILLIACVNFMNLATSRSMERAKEVGVRKAIGANKSNLILQFMSESLALVFFSGLLAIVLVLAFLPFLEAFSGKHLTYSSLMNGTTWSIFLLATTVTGLLAASYPALILASFQPIKVLKGAFSSSKGGTLLRRGLVVFQFCLSIALIAGTVIVFSQLNQLQQQDLGFQKAQRLIIDYNFDEKVNNNLEAIKNTLAKDKDVQSVTASRTVPGAFFPNAGTEIMSTDGKMTDFAPSLYEVDIDFIPNMGIKMVAGRAYSRDFPADTAHSLVINESAAKLWGYSNPQDIIGKQFRQWGKEGTVIGVVKDFNYLSLHRKIEPLTLRLEPGSSRYLAVNLQHVNQQTIDRIGKLWAELAPHRPFLYSFLDDNFNRQYEADYNFRRLFTAFSSLALFIACLGLLGLVTYTAQQRTKEIGVRKVLGASIYNLVLLLSSDFIRLLVIAICIATPLSWIAMNKWLDNFAYHIEPKWWMFAFAGLSAVFIALITVSYQTFKAAKANPVDSLRDE
>NZ_CP049333|1117571:1194056|1179844_1180588_+|WP_146191112.1|DBSCAN-SWA
MKPTKSRFFCREAQRSKMLFESQKKAENFMQYNNKEILNESGYAPVRSYHCIACDGWHLTSRREELDLPSKTELVLEAYKEVTDEKDKAKELRANGRQEKEAPSANALEGLRKKIELIRRSLKNKGSKTIIIKLIEGASRSLKDLEVTGQLKKSKGELEVHLGRLESRAMLLPDDEEAGIQTQIRVIERLFDNESNRILIRNLIYEALRTLRNMDGAMLQQDSKKALEKKLKNLALRCDHLRNNTSG
>NZ_CP049333|1117571:1194056|1191604_1192453_+|WP_165305685.1|DBSCAN-SWA
MKKYFILLILFFFVTSGGFAQSNSMLWKISGNGLKHDSYLFGTIHMLCPDDFEIKQKCLDALNSSEKVVFEVDLTKPENLQIMQAFAAPQPDFIKKFTESDIKSMDSILVPQQLSIKLLDYVSPVTAMSLFAMKGFNCPDPTKIKSFEAELAEIARIKGKSIGELETPDFQFNLLKDLITPKLFMESVFQLDKYPELTAKMVAAYKNENLTELTELIQDPTWMTAEQKEKLLAGRNVNWTTIIPNLVKEQSCFVAVGAGHLSGEKGLISLLREKGYSLTAIN
>NZ_CP049333|1117571:1194056|1181766_1182408_-|WP_108635849.1|protease|DBSCAN-SWA
MKFFDIFPTFSEAPYSYIVVPIILACSMIGFYHKPFFHALILHPYEIARGKRIHTLLTSALVHRNGIHLLFNCIVIFGLGYDMFAVLNQAYSIIIAQVFTILIFLLFIIVPNFVQTLFKKKDFRFTAVGASGLSSALFGFSTLFFPLQKINHLFIPWIHNATHYWLYMLLISFLLSFIKISRINRPLHLVAFILGSILALIISPYTFELKDAF
>NZ_CP049333|1117571:1194056|1175406_1176570_-|WP_108635853.1|DBSCAN-SWA
MQILPQSLSKLTRYTALLALFVAGKGDLKAQNIIQKLSKKFLSAEKDSTRSGSFMVLPAVGYAQETGVEYGLASSYNFYLDKSDPHIRTSTMTLMGTFTSKHQSNFKFQTDLWTKNNDYHFVSEIRYRNWPFNYYGIGMDTWKKDEERVDQKLFRLKLEAEKKVGNHLYSGINIQYDNFSIRSDSSDHIFNQSGLIGKEGGQQLLLGVSQLFDNRDNVSYSTRGYYAKLRLAYAPKLWTSTDFNGANLDIDLRGFIPLHKKVTLALQGIFRSTFGKTVPFYNYRELGGDMMMRGYYLGRYRDKNYLASQAELRYRFHPRFGIVGFSGIGSTFSKENSSRYVPSYGGGLRYFFSLEHNSSIRFDYSYGEQRTGEKRQSGFYLSLSEAF
>NZ_CP049333|1117571:1194056|1187832_1188306_+|WP_165305683.1|protease|DBSCAN-SWA
MKYILFPVIKIHKKYNFLFFLLFFFIDTILSYGFTQIINYFTFDFGAVESVANVPKWLLFVIMVIFAPLFETIVFQFVALELLLKLKISPSIAIVVSTVIFALFHNYNIPYMGYILLTGWILPYYYMALRDQGKSNKIVFVFMLHLIGNFISFFDYI
>NZ_CP049333|1117571:1194056|1173037_1174357_+|WP_108635855.1|DBSCAN-SWA
MRHGKVLNVIKIILLLAASVVGAYLLMKHEYVQAALIFCIMLYLGFNLYAQYNFLERQLVEFAEAVKYRDFTRRFLVKNPKSVEGQLFRAFNQINETYKEISIKQEIQHQYLDRVINMLNSAIIFYEMDTGKVMWVNDAFKQLFHLPHLGNIAGLKKKNPDLYEKTMLLDNGQQQMEPIQSSKGKIKLLIQSSSFETQDAVFRIVVYQNINEAIDETETKAWHKLLRVLTHEIMNSIAPISSLAETLNGRLDHFRGHEDIEDLKTGISTIKRRSEGLLHFAKSYRMINKVDQPQLAPIQVSQLFEHIYQLLEPTLIQKNIDVDIILKNTRLILYADVNLIEQVIINLMLNAIDAVKTREDAYISLSALEIDGKVQVRIEDNGSGIPADLQEQIFTPFFTTKKTGTGVGLTLSKQIMLLHKGTIFLNSVEGEGSAFILQF

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_165309558.1|1117571_1117769_+|transposase	transposase	NA	NA	NA	NA
WP_165305672.1|1118314_1118521_+	hypothetical protein	NA	NA	NA	NA
WP_165305673.1|1118577_1120056_+	thioredoxin family protein	NA	NA	NA	NA
WP_165305674.1|1120527_1120752_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_165305675.1|1120876_1121560_+	hypothetical protein	NA	NA	NA	NA
WP_108635876.1|1121698_1124095_-	ABC transporter permease	NA	NA	NA	NA
WP_108635875.1|1124122_1126528_-	ABC transporter permease	NA	NA	NA	NA
WP_108635874.1|1127459_1128077_+	hypothetical protein	NA	NA	NA	NA
WP_108635873.1|1128165_1130550_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_165305676.1|1130600_1133006_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_165305677.1|1133037_1135431_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_165305678.1|1135461_1137846_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_165305679.1|1137865_1140220_-	ABC transporter permease	NA	NA	NA	NA
WP_108635869.1|1140435_1142802_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_108635868.1|1142835_1145217_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_108635867.1|1145270_1147679_-	ABC transporter permease	NA	NA	NA	NA
WP_146191114.1|1147724_1148015_-	hypothetical protein	NA	NA	NA	NA
WP_108635866.1|1149530_1151933_-	ABC transporter permease	NA	NA	NA	NA
WP_108635865.1|1151986_1154404_-	ABC transporter permease	NA	NA	NA	NA
WP_108635864.1|1154614_1156990_-	ABC transporter permease	NA	NA	NA	NA
WP_108635863.1|1157038_1159444_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_108635862.1|1159478_1161896_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_104385115.1|1162000_1162684_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	9.0e-35	39.2
WP_108635861.1|1162784_1165151_-	ABC transporter permease	NA	NA	NA	NA
WP_108635860.1|1165186_1167562_-	ABC transporter permease	NA	NA	NA	NA
WP_108635859.1|1167645_1168899_-	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_165305680.1|1169221_1170082_+	TraB/GumN family protein	NA	NA	NA	NA
WP_146191113.1|1170258_1171641_+	TolC family protein	NA	NA	NA	NA
WP_108635856.1|1171672_1173034_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_108635855.1|1173037_1174357_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_108635854.1|1174624_1175152_+	hypothetical protein	NA	NA	NA	NA
WP_108635853.1|1175406_1176570_-	polymerase	NA	NA	NA	NA
WP_077437774.1|1177435_1178620_+	elongation factor Tu	V5L5J1	Insectomime_virus	2.0e-18	27.5
WP_028072657.1|1178877_1179072_+	preprotein translocase subunit SecE	NA	NA	NA	NA
WP_104384853.1|1179092_1179638_+	transcription termination/antitermination factor NusG	NA	NA	NA	NA
WP_146191112.1|1179844_1180588_+	hypothetical protein	NA	NA	NA	NA
WP_108635851.1|1180734_1181151_+	hypothetical protein	NA	NA	NA	NA
WP_108635850.1|1181152_1181476_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_165305681.1|1181632_1181770_+	hypothetical protein	NA	NA	NA	NA
WP_108635849.1|1181766_1182408_-|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_108636102.1|1182521_1183622_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_108635848.1|1183659_1185822_+	peptidase domain-containing ABC transporter	W8CYL7	Bacillus_phage	1.7e-47	30.7
WP_108635847.1|1185838_1187185_+	TolC family protein	NA	NA	NA	NA
WP_108635846.1|1187190_1187523_+	hypothetical protein	NA	NA	NA	NA
WP_165305682.1|1187613_1187763_+	hypothetical protein	NA	NA	NA	NA
WP_165305683.1|1187832_1188306_+|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_108635844.1|1188395_1188992_+|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_165305684.1|1190610_1191201_+	DUF3267 domain-containing protein	NA	NA	NA	NA
WP_165305685.1|1191604_1192453_+	TraB/GumN family protein	NA	NA	NA	NA
WP_108635841.1|1192569_1193043_+|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_108635840.1|1193387_1194056_+|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA