CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP028263	Lactobacillus plantarum strain SRCM102737 plasmid unnamed2, complete sequence	0 crisprs	NA	0	6
NZ_CP028262	Lactobacillus plantarum strain SRCM102737 plasmid unnamed1, complete sequence	0 crisprs	csa3	0	0
NZ_CP028261	Lactobacillus plantarum strain SRCM102737 chromosome, complete genome	2 crisprs	DinG,DEDDh,cas3,csa3,WYL,cas1,cas2,csn2	14	9

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 2883

Cucumis_melo_alphaendornavirus(100.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_160257356.1\|697_1927_+	hypothetical protein	NA	NA	NA	NA
WP_160257357.1\|1923_2883_+	hypothetical protein	A0A1W5ZN14	Cucumis_melo_alphaendornavirus	1.8e-12	30.8

DBSCAN-SWA_2

6552 : 11461

Hokovirus(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_160257360.1\|6552_7005_+	glycerol-3-phosphate cytidylyltransferase	A0A1V0SGE7	Hokovirus	1.9e-20	41.5
WP_160257361.1\|7306_7786_-	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	8.3e-11	41.3
WP_160257362.1\|7860_8088_-	hypothetical protein	NA	NA	NA	NA
WP_160257363.1\|8313_8661_-	DUF5388 domain-containing protein	NA	NA	NA	NA
WP_027822916.1\|8662_9463_-	ParA family protein	F0PIG8	Enterococcus_phage	2.1e-67	50.6
WP_160257364.1\|10438_11461_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	7.4e-33	31.6

DBSCAN-SWA_3

15947 : 25637

Staphylococcus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_160257364.1\|15947_16970_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	7.4e-33	31.6
WP_063486243.1\|18066_18621_+	recombinase family protein	A0A1J1J8Z4	Escherichia_phage	4.4e-32	44.6
WP_063486242.1\|19221_20403_-\|transposase	IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	1.2e-26	28.6
WP_063486241.1\|20898_22935_-	KUP/HAK/KT family potassium transporter	M1HZV6	Acanthocystis_turfacea_Chlorella_virus	4.7e-63	33.2
WP_027823033.1\|23852_24755_+	YitT family protein	M1Q1P6	Streptococcus_phage	8.2e-52	40.3
WP_160257368.1\|24862_25637_+\|transposase	IS5-like element ISLpl3 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.6e-27	53.2

DBSCAN-SWA_4

29626 : 37869

Streptococcus_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_160257369.1\|29626_30853_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	3.3e-88	48.0
WP_064578693.1\|32144_32990_-	LysM peptidoglycan-binding domain-containing protein	K4ID66	Lactobacillus_phage	4.3e-10	55.7
WP_063484976.1\|33453_33717_-	hypothetical protein	NA	NA	NA	NA
WP_160257370.1\|33938_34868_-\|transposase	IS30-like element ISLpl1 family transposase	H7BW47	unidentified_phage	5.7e-24	33.7
WP_011222016.1\|36716_37067_-	DUF5388 domain-containing protein	NA	NA	NA	NA
WP_015639692.1\|37068_37869_-	AAA family ATPase	F0PIG8	Enterococcus_phage	2.9e-53	41.9

DBSCAN-SWA_5

46920 : 56899

Streptococcus_phage(40.0%)

holin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_160257373.1\|46920_49056_+	DNA topoisomerase III	A0A1X9I6W8	Streptococcus_phage	6.6e-108	46.2
WP_034528478.1\|49178_49394_+	hypothetical protein	NA	NA	NA	NA
WP_094339146.1\|49397_50522_+	hypothetical protein	NA	NA	NA	NA
WP_021353390.1\|50677_50767_-\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_003561746.1\|51078_52254_+\|transposase	IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	1.8e-27	29.2
WP_160257374.1\|52474_53701_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	6.0e-90	48.3
WP_160257380.1\|54167_55478_-\|transposase	transposase	NA	NA	NA	NA
WP_160257381.1\|55751_56642_-\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	1.1e-154	98.2
WP_016382199.1\|56647_56899_-\|transposase	IS3 family transposase	Q6J1X3	Lactobacillus_phage	2.7e-37	95.2

DBSCAN-SWA_6

61619 : 62552

Staphylococcus_prophage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_160257378.1\|61619_62552_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-38	36.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP028261

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP028261_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP028261_1

668118-668419

Orphan

Consensus_repeat	Method
GCTACTGCTAAGGCTCAAAGTACAGCTGACAATGCGTTTAGCCAAGC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP028261_1

>merge|NZ_CP028261|1|668118-668419|CRISPRCasFinder
AAGATTATCAATGCTCAAAATACGGCTGATAATGCGGCTAGCCAAGCAGGAAATGCTGATAGCGCTGCTTTAATTGCACAGTCTACAGCGAATGCCGCTAAATCAGCCGCAGATAGCAATTACAACTACGCCAATTCAGAAATAGCCGTCCAGTCTAATGCTACTGCTAAGGCTCAAAGTACAGCTGACAATGCGTTTAGCCAAGCTCAGGCAGTTGGTAGCCAAGCTAGTGCTGGGATAAGCAACAACTCTACAGCTACTGCTAAGGCTCAAAGTACAGCTGATAATGCGTTTAGCCAAGC

>NZ_CP028261|1|1|668118-668419|CRISPRCasFinder
AAGATTATCAATGCTCAAAATACGGCTGATAATGCGGCTAGCCAAGC	AGGAAATGCTGATAGCGCTGCTTTAATTGCACAGTCTACAGCGAATGCCGCTAAATCAGCCGCAGATAGCAATTACAACTACGCCAATTCAGAAATAGCCGTCCAGTCTAAT
GCTACTGCTAAGGCTCAAAGTACAGCTGACAATGCGTTTAGCCAAGC	TCAGGCAGTTGGTAGCCAAGCTAGTGCTGGGATAAGCAACAACTCTACA
GCTACTGCTAAGGCTCAAAGTACAGCTGATAATGCGTTTAGCCAAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP028261.1\|WP_016058335.1\|658346_658538_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028261.1\|WP_003645248.1\|677835_678195_-\|YisL-family-protein	unknown	unknown	gnl\|CDD\|237465
NZ_CP028261.1\|WP_016058333.1\|657126_657765_+\|major-tail-protein	unknown	unknown	gnl\|CDD\|309671
NZ_CP028261.1\|WP_069302499.1\|656305_656746_+\|phage-tail-protein	unknown	unknown	unknown
NZ_CP028261.1\|WP_160257275.1\|673908_674439_+\|holin	unknown	unknown	gnl\|CDD\|227833
NZ_CP028261.1\|WP_160257272.1\|671871_672450_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028261.1\|WP_011101374.1\|675505_675931_-\|lipoprotein	unknown	unknown	unknown
NZ_CP028261.1\|WP_160257271.1\|670827_671079_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028261.1\|WP_069302500.1\|656742_657126_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028261.1\|WP_046947715.1\|657966_658350_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028261.1\|WP_011101375.1\|677220_677736_+\|GtrA-family-protein	unknown	unknown	gnl\|CDD\|377229
NZ_CP028261.1\|WP_003644258.1\|676095_677166_-\|membrane-protein	unknown	unknown	unknown
NZ_CP028261.1\|WP_069302498.1\|655953_656316_+\|phage-head-closure-protein	unknown	unknown	gnl\|CDD\|273692
NZ_CP028261.1\|WP_160257273.1\|672461_673634_+\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|119377
NZ_CP028261.1\|WP_160257274.1\|673633_673897_+\|holin	unknown	unknown	gnl\|CDD\|371241
NZ_CP028261.1\|WP_069302497.1\|655631_655970_+\|phage-gp6-like-head-tail-connector-protein	unknown	unknown	gnl\|CDD\|153446
NZ_CP028261.1\|WP_069302502.1\|663844_665617_+\|phage-tail-protein	unknown	unknown	gnl\|CDD\|368574
NZ_CP028261.1\|WP_069302503.1\|665683_668053_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377677
NZ_CP028261.1\|WP_069302501.1\|658550_663773_+\|phage-tail-protein	unknown	unknown	gnl\|CDD\|380090
NZ_CP028261.1\|WP_003643144.1\|675943_676063_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP028261.1\|WP_011101375.1\|677220_677736_+\|GtrA-family-protein	gnl\|CDD\|377229	pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of undecaprenyl phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane. Another member of this family is a DTDP-glucose-4-keto-6-deoxy-D-glucose reductase, which catalyzes the conversion of dTDP-4-keto-6-deoxy-D-glucose to dTDP-D-fucose, which is involved in the biosynthesis of the serotype-specific polysaccharide antigen of Actinobacillus actinomycetemcomitans Y4 (serotype b). This family also includes the teichoic acid glycosylation protein, GtcA, which is a serotype-specific protein in some Listeria innocua and monocytogenes strains. Its exact function is not known, but it is essential for decoration of cell wall teichoic acids with glucose and galactose.	2.272e-15
NZ_CP028261.1\|WP_003645248.1\|677835_678195_-\|YisL-family-protein	gnl\|CDD\|237465	PRK13673, PRK13673, hypothetical protein; Provisional.	3.81516e-23
NZ_CP028261.1\|WP_016058333.1\|657126_657765_+\|major-tail-protein	gnl\|CDD\|309671	pfam04630, Phage_TTP_1, Phage tail tube protein. This is a family of phage tail tube proteins from Myoviridae.	6.73485e-69
NZ_CP028261.1\|WP_069302498.1\|655953_656316_+\|phage-head-closure-protein	gnl\|CDD\|273692	TIGR01563, hypothetical_protein_AGR_C_1752, phage head-tail adaptor, putative, SPP1 family. This family describes a small protein of about 100 amino acids found in bacteriophage and in bacterial prophage regions. Examples include gp9 of phage HK022 and gp16 of phage SPP1. This minor structural protein is suggested to be a head-tail adaptor protein (although the source of this annotation was not traced during construction of this model). [Mobile and extrachromosomal element functions, Prophage functions].	1.30979e-07
NZ_CP028261.1\|WP_160257273.1\|672461_673634_+\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|119377	cd06415, GH25_Cpl1-like, Cpl-1 lysin (also known as Cpl-9 lysozyme / muramidase) is a bacterial cell wall endolysin encoded by the pneumococcal bacteriophage Cp-1, which cleaves the glycosidic N-acetylmuramoyl-(beta1,4)-N-acetylglucosamine bonds of the pneumococcal glycan chain, thus acting as an enzymatic antimicrobial agent (an enzybiotic) against streptococcal infections. Cpl-1 belongs to the CP family of lysozymes (CPL lysozymes) which includes the Cpl-7 lysin. Cpl-1 has a glycosyl hydrolase family 25 (GH25) catalytic domain with an irregular (beta/alpha)5-beta3 barrel and a C-terminal cell wall-anchoring module formed by six similar choline-binding repeats (ChBr's). The ChBr's facilitate the anchoring of Cpl-1 to the choline-containing teichoic acid of the pneumococcal cell wall. Other members of this domain family have an N-terminal CHAP (cysteine, histidine-dependent amidohydrolases/peptidases) domain similar to that of the firmicute CHAP lysins and associated with endopeptidase activity. The Cpl-7 lysin is also included here as is LysB of Lactococcus phage, and the Mur lysin of Lactobacillus phage.	1.41744e-63
NZ_CP028261.1\|WP_160257275.1\|673908_674439_+\|holin	gnl\|CDD\|227833	COG5546, COG5546, Small integral membrane protein [Function unknown].	0.00102619
NZ_CP028261.1\|WP_069302503.1\|665683_668053_+\|hypothetical-protein	gnl\|CDD\|377677	pfam06605, Prophage_tail, Prophage endopeptidase tail. This family is of prophage tail proteins that are probably acting as endopeptidases.	2.71369e-13
NZ_CP028261.1\|WP_069302502.1\|663844_665617_+\|phage-tail-protein	gnl\|CDD\|368574	pfam05709, Sipho_tail, Phage tail protein. This family consists of several Siphovirus and other phage tail component proteins as well as some bacterial proteins of unknown function.	7.94224e-07
NZ_CP028261.1\|WP_069302497.1\|655631_655970_+\|phage-gp6-like-head-tail-connector-protein	gnl\|CDD\|153446	cd08054, gp6, Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins. The bacteriophage HK97 gp6 protein is critical in the assembly of the connector, a specialized structure that serves as an interface for head and tail attachment, as well as a point at which DNA exits the head during infection by the bacteriophage. It forms a dodecameric ring structure that comprises the middle ring of the connector, located between the portal protein (attached to the head) and the gp7 ring (attached to the tail). It is a component of the mature phage and the absence of HK97 gp6 results in defective head-tail joining and the absence of mature phage particles. Although the crystal structure of HK97 gp6 shows an unexpected 13-mer ring, the biological form present in the mature phage is believed to be a dodecamer.	7.85316e-20
NZ_CP028261.1\|WP_069302501.1\|658550_663773_+\|phage-tail-protein	gnl\|CDD\|380090	pfam18013, Phage_lysozyme2, Phage tail lysozyme. This domain has a lysozyme like fold. It is found in the tail protein of various phages probably giving them the ability to degrade the host cell wall peptidoglycan layer.	1.69997e-24
NZ_CP028261.1\|WP_160257274.1\|673633_673897_+\|holin	gnl\|CDD\|371241	pfam10779, XhlA, Haemolysin XhlA. XhlA is a cell-surface associated haemolysin that lyses the two most prevalent types of insect immune cells (granulocytes and plasmatocytes) as well as rabbit and horse erythrocytes. This family has had DUF1267, pfam06895, merged into it.	5.43654e-10

>NZ_CP028261.1|WP_069302503.1|665683_668053_+|hypothetical-protein
MALNNQYLILDPNLKRIGTLTVDGATKFSNDSVKIQLADADTTSTSYDDDVNVGTKDSYTGTINLNAQSKKFDHQGSLDVLQGQPDSDKVVAGNNLAYYDALSGHWYVMRIYSVEESNTAAVKHVTTANFTNLCLYNLAHHYPVAITASDSSIQTAFNQCFNATGWTLDYQTTNVMTPSIAIDGKTKASTLLQTLIQTYDVEIDPYVEIDSQGNITKKVCVITDQLNANVVYNEAIFGKNMTSLKRTTVSNPITKLIPYGANGNTIGLVNDGKSYIVDDEANQTYNPDWQSGLYYEGVVTANSIEDPAGLKAWAEEMLQLYNHPRTYYEVNVTSKFNPPLGATIRFKDELIKPALDASGRVIQRTISFANPYGNTVGFGEYVTVPVATPAWMQGYQSAINSAIEKAKEDASSVKPVALTPDGNNFTDTTQTKRLILQAWEGNTNISAYIDNKGFIWHRYNTDGTLDTSFNQTGYLVQAAYNAVGTLHGTIETRYIQDEPEIKLKTSAIRSLGSFSPDNSTLGITEAAQYMCPLSNGQYITSRAINQSTTGDTMFVLHDTNFNPISKMIVSHGGHGSSFSIEEVDGTIYIWSATKPNLNVNEYAVSRIPYLANVTLGNDDDRITRFCTVDRYIRVSVDFKHGYVLCGYVNGKHDVLRLDEVKQGNYDVLYSFDVANYGFDESKQTYQSQGIDFPYVYFHSGDYNMKDPRMVYAVNVVHGGQEFASNYLLDMNLGLTDDVIEPETCNIIYSQTNQPELLVTFNCKYQGDSLERVFVIPIKERLPMNTISND
>NZ_CP028261.1|WP_069302502.1|663844_665617_+|phage-tail-protein
MSVLNKNDFEYAGLNSRDDLQAIMGAVTLPSAPAMAEQATDIPAMYGNQFNGMDYTSRTISIPITIIARGSQDKYNQIMHNLSGLLLSDDPSDNGKEYPLVFGFEPKVTYWGHITAISDPQFINQGTWDATLTITFVQSDPRATLPQVEKPLNNGLNTITVDGTARTEPVIQVIPKRDLKYIGFSLNGGQFGLGPESPGDQATAVQPYTKVVDDPLGTMAMWTNDANAISNMKTGEAYTYQGHSEIKTTTNVMRPAVTSAGYDFGTIPTTGEDRWYGPAYRYTGMTNSLTDWRVRTGIHQFKYSGTHNGRAMGRVEVLLLDPNGNTIGRFGMRDMAYGAKPMARLQICEPGSTLEYGDHYTDLYYGSGPAGSFTNKPDQKIQIKTGTTTKTVTKYGRSKSGKVTKKTVNETVDTYTTVVNKEEDSALAGAWLVLDITKRGQVFTWSITQYSTKTGRPFLDPNIHMLVHGTYVDTQNKYQTALGGIGSVFLKHPITEDKYKIAYRNPFMSMTDLQIWQVNKVDTTKPTYIANAGEEIVMDCESDTVTVNGKLVPPVWSTDFPKLKPGVNGLSMIGDLDDAQITLKYLPRIL
>NZ_CP028261.1|WP_069302501.1|658550_663773_+|phage-tail-protein
MATEKIQGYEFAINMDDGGMTRTLREIKNEAKLLKSGMQANFAEIRSGEGIMAAYAGKVKDAGRAIEAQRLVIERLKNEQNGLDQTTQKGREAYVKYENQINAAKRSIASLEGQQERAQKSLDLQKSGVLQLKDATEISAKVTDSYVAKLKAEGHEFEANKVKASGLHQSYNELNKQLEAEQSRLNKIASASGNSSKEFKEQQIRVNELGTKIAQTRVKMKELDEQLSKKPQSGLTSVISQLNRVNEHADKANHLFGKILGAHLVANGITSAFQSITSHIHEAISAGMEYEKEQQKMVATWLTLTGTVGKSNAMVKTINDLSVKTGQAVDVVNELEQGFYHLHSNKKESDELTKSMLNMSDAVGLDKQQIQAVTQDMVNGLSRGKANAGMLNQISQYFPMFREQLAKYESGLKKTGDTAASTGKGAAKAVSAYNKKMTLMFEGMHYGTNNSLSDLETYRQKGIVSAQQFTVFSKQIASGHKVTNAEIKQAIKVNSQYAAQQETNAQKTHTSSKVTVADLSEMAKEGKISAKDIENTFNQLGSGKYDKAADNMLHTMVGMERTIKARVPALIGDIEKPILTAQNPIYGAVSKWVSDKRTDKEFSKVGVAAEKGISTITKAFAKAFDVKSAPKAMNDAMDNLAKGVTKASNSIAKNAPEIVNFFKTVKNLGGLGFETLIESLKITNSILKPLLSMVGGHTETIAKFGAAWWLTSKAVKETSSVLSTFKKISDTVSWAEKVLGIKQETKALEEQNAVLKTNTELSMASEENIGTGYRRVKGRKAGNIGADLSSISVEAENTEKIAKSSKWSLLGGTIGTRIINGAGLAMTAWDAGSSIAKAVSSGKASDKYKATGKTAGTLIGGGIGAALGSVIPGAGTAAGAMLGASIGDGVGGTKTANTIVKRISDALKGKSIEAPKIKTESTKRSLSDLGKAYSSYYSKKQKQDLNDVNVLHKAGMLTDAEYKKQLASIKKNDSETNRFEKMSASDRNAIAKYYAQQKASIISKWNARERKTSSSWDAKIASDERRFGANSIIVQKDMSKKKTAIKAEENKKSAALDKLRIKSATETTAQEARLHTTLTGKIKSAANKQNDILRNLAKSKGKITREQANDAISQSNKEYKKTVSLANQEYKDRVSAAEKQHNKVIKAAERQASEAISQAKNQYSKTVDAAKNQYSGNSKYAEKQRAAIISKAKDQKQKSIDNALEQENKTEQHADRQYKHTTDDADKQRSQVVKHAKDQNSSVVDQAKSQSKGVLGHAVKQANGSMKAADKQGSGIHSIWKNITSFFSNLVKGFGIKPINVGAYPSGYTPVTMGAYASGGIVGTARALVGEGGVEAKIDRDNGKVSFLGMNGAEVVNVKPGDQILNAGDTAKLFNGGLGHTLPGYAKGTIDIASFLKKIKSGATSIFDSVSDKAMDALSKITHPLKTLKSMALKTFDPTKTPGVGSIGHDLGKGLVDRALKGFAKAISDLADNFGGGVGNIKLSGSVASRARELARAFKHGYPASNNGGIAGVLGNWVIESNLTPTAIDPLDHGTGLGQWTFTRETALRSWLRKHGYAWDSAAGQINYALNEPGESSLLKSVLRMTNPTEAAYKFFATWESGGAMNGTGGLRESQASAVYRYIKGFENGGFGNKAGVYKLFEGNLPEAIVPMDLSKRSRAYQIMQQIMAKFGAQDGANVINTGNDQIDSDEAFKQRVIASLDALVTGQGDVKAVVANSDVVNAVKSNTKKTSQYSQMMGY
>NZ_CP028261.1|WP_016058335.1|658346_658538_+|hypothetical-protein
MIWQLDNFIQDIDYIANQLISQGILPSDFYQSSFSEMQTALNAKSRKDRVQDPLELARQIGAL
>NZ_CP028261.1|WP_046947715.1|657966_658350_+|hypothetical-protein
MAKSVKFDGKKIGTGTQYTLIDSGQNVEKMAEAYKKFIKTTEETEDSITGVVELTPKLAKVVAETTCDLLELNASQKKRVMSMEFSVSDEYDLFNDCLKQFLGVELTSVGNSSDQEEEEDPKLPKPE
>NZ_CP028261.1|WP_016058333.1|657126_657765_+|major-tail-protein
MATLGLNMLYTGIKADDGSTVIDADKGLSAAGVYPIDTSKANGNLGTKTANITGLSGTVSKITGNNEVVDVSNPPSAPSVAIDSNEINFIVKQKLLGRVSDGKGGYSDTDKPVEAGLIIESRSPIFRTAIYYCFGRGIFNEAGQNIQTNTDTAETRDDDNLTFTALNYDGFGGQPYKVYAESDPKFDKQAMFDAVFPGQTFYKNASNGTSGQ
>NZ_CP028261.1|WP_069302500.1|656742_657126_+|hypothetical-protein
MTPVAFIKSIIVANINEIPELAVEHIHSFFIPINDTSSDEPIVVISGLPERSQDYGNGIPFQSTKQVQIQLYYPKDYLGDMDAIESGLKQVLLTNDIRCYSDAGQTLTPDSGSIMNTLKFNYIKEAI
>NZ_CP028261.1|WP_069302499.1|656305_656746_+|phage-tail-protein
MANEIKHADSFEHILDTMAEGFGREEKLKANAAGADQFIKIMKPKIPVGKLRKAHGHAEKVHLRDSLIAVDHPNGSVNVGFTAKGEKGYIARFQNDGWDVVDRNGSKHSHVSGKHFWETTQREAKGQVGKAVVEQLKTAMDKKVGK
>NZ_CP028261.1|WP_069302498.1|655953_656316_+|phage-head-closure-protein
MTKAINPARMNFRLEFGTQAATGKVNPNTGNPITDFVPQFSLYAGEWSLSFQQRLALNGDTSQQNAVYFVRHNRKIATGMQLRRNHQDVYQIDDVAYDDGLPPDGFDLITCHKVVIGRGE
>NZ_CP028261.1|WP_069302497.1|655631_655970_+|phage-gp6-like-head-tail-connector-protein
MAANLETLKSSLRIDDDDDDELLTGYLSAATSYIKQAIGDDNSVLGFYEMEGVSDLFETAVYALAGSYWTYRTSITAIAVNPVDLVVDSIIGQLRGLYSQKQYEAGTYDESN
>NZ_CP028261.1|WP_160257271.1|670827_671079_+|hypothetical-protein
MDSILITNYKPDYTNNIMTISVQINTLGISSQVSITMDEFNTAIAGGAGGADRVKLKVLNTLIDSLTALKPVTTTTTTTTQEA
>NZ_CP028261.1|WP_160257272.1|671871_672450_+|hypothetical-protein
MADITHGMWIKDGKAVDTVYQGGTKVYGRNLVAGTSEPFTMQYGIPNTVWNADKKRAEISLPITALSGEVLPKNNFNYTVTPGMSYTQSIYVSTDAPLTGTAVQVTWFTNGNGHNVAGTTNITSVSKNVYRITCTYTWPVNRTDNTPRLFDIMNLTYVFDFTKGTFLYFYQPKIEQGTIATPYSLAPEDVLN
>NZ_CP028261.1|WP_160257273.1|672461_673634_+|LysM-peptidoglycan-binding-domain-containing-protein
MNKHKLKALILMIGAIFMAFFMVNLNSQASTSRDQGVDWSKYNSNSGTFGYSTDKFVLSQAGGFYGGTNIPQTTYASQVKSAQQAGKRVHTYLWDGVGGNMTNGRAMMAYYLPRVKTPKGSIVALDYEDGASNNVTANTNVILAQMKMIKDAGYTPMLYSGKAYLNAHVNTSAIVKAYGTCLWLAEYPDYLVRTSPDYTWFPSMDGVAIFQFTSMYKAGGLDGNVDLTGITKSGYTTASKKQAQTNVKKAQAAKKATFKVVKYSQRGVFYPNRTLAVRYTDNDKVSQVATYYKGESVIYNAVIIEHDYVWARYTRSNGLYGFIKLGVTNGHDYGKRATGQLVSHTYYTVKSGDSWWTIAQRNGLSMTTLASQNGKSIYTTIYPGQRLVVR
>NZ_CP028261.1|WP_160257274.1|673633_673897_+|holin
MAQYDDTTKLLMDIQKDVAATKTKVDNIEEKLNRIDDIGDKADKALAKSIEASHQIDRVTTIQNWLIGVLVSGVLVTLVIYIAEKFL
>NZ_CP028261.1|WP_160257275.1|673908_674439_+|holin
MTKFLNVIQATLKANYKKPAYWAQIIGSVLIIGLAVATVFFGVKIDANAVVLVITAVGAILAFVGAITDNSILEDTGNTIKTKSSTLAYTEQTVVEALAEAQAKIEAANSAAASQAEAQASQAVVAAYSQAASAAAVGDTATASSAATLASSLAANLDTNAQPNAETTSESASQAS
>NZ_CP028261.1|WP_011101374.1|675505_675931_-|lipoprotein
MTRAILISFCALFLLAGCTSQAEPSISTKQANSVAAANRAEQTSRANAAADASAKKQSGDHYQATDDHITSATSAVAAVGQVLNDPKQQTFGVVPTANQDAHGHHYYQVDAYQKTANGGRGHYLNSYFVYLDGSITTKQAN
>NZ_CP028261.1|WP_003643144.1|675943_676063_-|hypothetical-protein
MKKLILVILLLLSIGVMTIVDSNIIRQAPYPSLSQEQTK
>NZ_CP028261.1|WP_003644258.1|676095_677166_-|membrane-protein
MGWSLILKLICNSFWSELFMRTYLFIAGLILACLILIIILIAVLVHLHHVNQAADKQAALLKSIRQRLVHQTLTNQEQDRQITKLQTQNNGFRNRLNQAVPHPVAVPQTRRINANSRAIFRSYVIGLDYYQKEFEAALADASARGYFKPYGGYNDSGLKADYLYAKKYRVDANANIGEIQLVEEVDGAERSVRVELKVAEHGYTIGYLPKKQVDEAFNVIDIYANSVMTLSSKTNLTGGEWKMAIDAVDEMQYLNDPNAQNRALPDYGAIDTPLKIKTGKKSYFLQFTLYEMEISNDEIPLYSLVDTVDGQRGSIVEVDAGPISYVIDVQAGPQTGSKITVIPEQIDRVIWVPNWK
>NZ_CP028261.1|WP_011101375.1|677220_677736_+|GtrA-family-protein
MLLYNIFELEETVANGVQWLIKIYHQYQYFWKYALFGFMAALVNVLVFWVLHSVLAEHYLFSNTIAWVLATLFSFFTNKAVVFQSKSQDFWHWCREFISFMLTRGLSYFFDTFLMFVGISLLFWAPLLVKIIDQVLVGLFNYGTSRLIFMESNQKMRMRQQIMKRLSDRNN
>NZ_CP028261.1|WP_003645248.1|677835_678195_-|YisL-family-protein
MYLLGHIIGWLWLMLTVAIGLSRHSVKSANRFLILSRIGYLLIIITGVALAIRTLSGNWWLTLLKVILGLGTIGLIEVAFARKQESHLNSGLVTLLVCGTLLTIICGIGLHWQLTGNLI

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Crispr_ID: NZ_CP028261_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP028261_2

2830435-2831952

TypeI-A,TypeII-A?

Consensus_repeat	Method
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	PILER-CR
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CRISPRCasFinder
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CRT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CRT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	PILER-CR
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	PILER-CR

41 spacers

csn2,cas2,cas1,csa3

The CRISPR arrays of NZ_CP028261_2

>merge|NZ_CP028261|2|2830435-2831952|PILER-CR,CRISPRCasFinder,CRT,CRT,PILER-CR,PILER-CR
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACAAAATGGATTTCTGAGCATTACTGTCCGACGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGACTATACCAATGAGGTCGAAGCATGGTTAGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGTTTTTAGCAGATTTAATGAATTCGTCATCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTAGGTTTACTCATGGTAAATCCTCCTATGTGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACAAAATAAATTTAAGGTTGCGCAACACAATGGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACAACTCATCATAAATGACGTCTTTTACCGAGGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACAAAATAGTTCGACGAAAAAGCCGAAAGAGAGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGCGGCCACGACCGCCATGGGTGTCAGCGCCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTCGGATAACTTAGCGGCGGCGTATCCCTGCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTACCGGGTGTTAAATCTGAATTAGAAGCGCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTCATCAACATTTTCATCAACGCGACTAGTTGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACATAGTGACAGCATCTGTTTTCGGACCAATCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGAGGCTTGCACTAGTGAGTTCAATCGTTATGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTGTCCATACGAGCAGCGTTGGCACTTATTCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGTATTATTATCAACGTCCCGCATTGCGTTAGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACAGGATATATGAAATTAGTACATGTACTAGTGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACACGTCTTTCAGCCCAGTAAACTGCTCAAGTGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTTGAATACCATTCCTTGTTTATACTCCATCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACCAATACCATAGTAGTCAATTATTACACGTCGTCTTGAATAGTAGTCAATTATTACACGTCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGTGACGTGCTCCCATGTGACCCGAATTGACGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACCGACTCTAATGGATATTTTCAATCATAGCAGTCTTGAATAGTAGTCATATCAAATAGGTTTAGAACGATGGTGCTGTTGCACGTGATCCCGCGCTTGTCTTGAATAGTAGTCATATCAAGCAGGTTTAGAAT

>NZ_CP028261|2|1|2830435-2831064|PILER-CR
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATGGATTTCTGAGCATTACTGTCCGAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GACTATACCAATGAGGTCGAAGCATGGTTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTTTTTAGCAGATTTAATGAATTCGTCATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TAGGTTTACTCATGGTAAATCCTCCTATGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATAAATTTAAGGTTGCGCAACACAATG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AACTCATCATAAATGACGTCTTTTACCGAG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATAGTTCGACGAAAAAGCCGAAAGAGA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GCGGCCACGACCGCCATGGGTGTCAGCGCC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TCGGATAACTTAGCGGCGGCGTATCCCTGC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTACCGGGTGTTAAATCTGAATTAGAAGCGCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTCATCAACATTTTCATCAACGCGACTAGTTGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACATAGTGACAGCATCTGTTTTCGGACCAATCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGAGGCTTGCACTAGTGAGTTCAATCGTTATGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTGTCCATACGAGCAGCGTTGGCACTTATTCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTATTATTATCAACGTCCCGCATTGCGTTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AGGATATATGAAATTAGTACATGTACTAGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ACGTCTTTCAGCCCAGTAAACTGCTCAAGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTTGAATACCATTCCTTGTTTATACTCCATCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACCAATACCATAGTAGTCAATTATTACACGTCGTCTTGAATAGTAGTCAATTATTACACGTCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGTGACGTGCTCCCATGTGACCCGAATTGACGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CGACTCTAATGGATATTTTCAATCATAGCA
GTCTTGAATAGTAGTCATATCAAATAGGTTTAGAAC	GATGGTGCTGTTGCACGTGATCCCGCGCTT


>NZ_CP028261|2|2|2830435-2831952|CRISPRCasFinder
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATGGATTTCTGAGCATTACTGTCCGAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GACTATACCAATGAGGTCGAAGCATGGTTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTTTTTAGCAGATTTAATGAATTCGTCATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TAGGTTTACTCATGGTAAATCCTCCTATGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATAAATTTAAGGTTGCGCAACACAATG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AACTCATCATAAATGACGTCTTTTACCGAG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATAGTTCGACGAAAAAGCCGAAAGAGA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GCGGCCACGACCGCCATGGGTGTCAGCGCC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TCGGATAACTTAGCGGCGGCGTATCCCTGC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TACCGGGTGTTAAATCTGAATTAGAAGCGC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TCATCAACATTTTCATCAACGCGACTAGTT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ATAGTGACAGCATCTGTTTTCGGACCAATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GAGGCTTGCACTAGTGAGTTCAATCGTTAT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TGTCCATACGAGCAGCGTTGGCACTTATTC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTATTATTATCAACGTCCCGCATTGCGTTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AGGATATATGAAATTAGTACATGTACTAGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ACGTCTTTCAGCCCAGTAAACTGCTCAAGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTGAATACCATTCCTTGTTTATACTCCATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CAATACCATAGTAGTCAATTATTACACGTCGTCTTGAATAGTAGTCAATTATTACACGTC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTGACGTGCTCCCATGTGACCCGAATTGAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CGACTCTAATGGATATTTTCAATCATAGCA
GTCTTGAATAGTAGTCATATCAAATAGGTTTAGAAC	GATGGTGCTGTTGCACGTGATCCCGCGCTT
GTCTTGAATAGTAGTCATATCAAGCAGGTTTAGAAT

>NZ_CP028261|2|1|2830435-2831724|CRT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATGGATTTCTGAGCATTACTGTCCGAC
	AAAATGGATTTCTGAGCATTACTGTCCGAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GACTATACCAATGAGGTCGAAGCATGGTTA
	GACTATACCAATGAGGTCGAAGCATGGTTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTTTTTAGCAGATTTAATGAATTCGTCATC
	GTTTTTAGCAGATTTAATGAATTCGTCATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TAGGTTTACTCATGGTAAATCCTCCTATGT
	TAGGTTTACTCATGGTAAATCCTCCTATGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATAAATTTAAGGTTGCGCAACACAATG
	AAAATAAATTTAAGGTTGCGCAACACAATG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AACTCATCATAAATGACGTCTTTTACCGAG
	AACTCATCATAAATGACGTCTTTTACCGAG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATAGTTCGACGAAAAAGCCGAAAGAGA
	AAAATAGTTCGACGAAAAAGCCGAAAGAGA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GCGGCCACGACCGCCATGGGTGTCAGCGCC
	GCGGCCACGACCGCCATGGGTGTCAGCGCC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TCGGATAACTTAGCGGCGGCGTATCCCTGC
	TCGGATAACTTAGCGGCGGCGTATCCCTGC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TACCGGGTGTTAAATCTGAATTAGAAGCGC
	TACCGGGTGTTAAATCTGAATTAGAAGCGC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TCATCAACATTTTCATCAACGCGACTAGTT
	TCATCAACATTTTCATCAACGCGACTAGTT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ATAGTGACAGCATCTGTTTTCGGACCAATC
	ATAGTGACAGCATCTGTTTTCGGACCAATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GAGGCTTGCACTAGTGAGTTCAATCGTTAT
	GAGGCTTGCACTAGTGAGTTCAATCGTTAT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TGTCCATACGAGCAGCGTTGGCACTTATTC
	TGTCCATACGAGCAGCGTTGGCACTTATTC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTATTATTATCAACGTCCCGCATTGCGTTA
	GTATTATTATCAACGTCCCGCATTGCGTTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AGGATATATGAAATTAGTACATGTACTAGT
	AGGATATATGAAATTAGTACATGTACTAGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ACGTCTTTCAGCCCAGTAAACTGCTCAAGT
	ACGTCTTTCAGCCCAGTAAACTGCTCAAGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTGAATACCATTCCTTGTTTATACTCCATC
	TTGAATACCATTCCTTGTTTATACTCCATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CAATACCATAGTAGTCAATTATTACACGTCGTCTTGAATAGTAGTCAATTATTACACGTC
	CAATACCATAGTAGTCAATTATTACACGTC
GTCTTGAATAGTAGTCAATTATTACACGTCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTGACGTGCTCCCATGTGACCCGAATTGAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CGACTCTAATGGATATTTTCAATCATAGCA
GTCTTGAATAGTAGTCATATCAAATAGGTTTAGAAC	GATGGTGCTGTTGCACGTGATCCCGCGCTT


>NZ_CP028261|2|2|2830435-2831952|CRT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATGGATTTCTGAGCATTACTGTCCGAC
	AAAATGGATTTCTGAGCATTACTGTCCGAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GACTATACCAATGAGGTCGAAGCATGGTTA
	GACTATACCAATGAGGTCGAAGCATGGTTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTTTTTAGCAGATTTAATGAATTCGTCATC
	GTTTTTAGCAGATTTAATGAATTCGTCATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TAGGTTTACTCATGGTAAATCCTCCTATGT
	TAGGTTTACTCATGGTAAATCCTCCTATGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATAAATTTAAGGTTGCGCAACACAATG
	AAAATAAATTTAAGGTTGCGCAACACAATG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AACTCATCATAAATGACGTCTTTTACCGAG
	AACTCATCATAAATGACGTCTTTTACCGAG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATAGTTCGACGAAAAAGCCGAAAGAGA
	AAAATAGTTCGACGAAAAAGCCGAAAGAGA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GCGGCCACGACCGCCATGGGTGTCAGCGCC
	GCGGCCACGACCGCCATGGGTGTCAGCGCC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TCGGATAACTTAGCGGCGGCGTATCCCTGC
	TCGGATAACTTAGCGGCGGCGTATCCCTGC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TACCGGGTGTTAAATCTGAATTAGAAGCGC
	TACCGGGTGTTAAATCTGAATTAGAAGCGC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TCATCAACATTTTCATCAACGCGACTAGTT
	TCATCAACATTTTCATCAACGCGACTAGTT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ATAGTGACAGCATCTGTTTTCGGACCAATC
	ATAGTGACAGCATCTGTTTTCGGACCAATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GAGGCTTGCACTAGTGAGTTCAATCGTTAT
	GAGGCTTGCACTAGTGAGTTCAATCGTTAT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TGTCCATACGAGCAGCGTTGGCACTTATTC
	TGTCCATACGAGCAGCGTTGGCACTTATTC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTATTATTATCAACGTCCCGCATTGCGTTA
	GTATTATTATCAACGTCCCGCATTGCGTTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AGGATATATGAAATTAGTACATGTACTAGT
	AGGATATATGAAATTAGTACATGTACTAGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ACGTCTTTCAGCCCAGTAAACTGCTCAAGT
	ACGTCTTTCAGCCCAGTAAACTGCTCAAGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TTGAATACCATTCCTTGTTTATACTCCATC
	TTGAATACCATTCCTTGTTTATACTCCATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CAATACCATAGTAGTCAATTATTACACGTCGTCTTGAATAGTAGTCAATTATTACACGTC
	CAATACCATAGTAGTCAATTATTACACGTC
GTCTTGAATAGTAGTCAATTATTACACGTCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTGACGTGCTCCCATGTGACCCGAATTGAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CGACTCTAATGGATATTTTCAATCATAGCA
GTCTTGAATAGTAGTCATATCAAATAGGTTTAGAAC	GATGGTGCTGTTGCACGTGATCCCGCGCTT
GTCTTGAATAGTAGTCATATCAAGCAGGTTTAGAAT

>NZ_CP028261|2|2|2831359-2831592|PILER-CR
	AAAATGGATTTCTGAGCATTACTGTCCGAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GACTATACCAATGAGGTCGAAGCATGGTTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTTTTTAGCAGATTTAATGAATTCGTCATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TAGGTTTACTCATGGTAAATCCTCCTATGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATAAATTTAAGGTTGCGCAACACAATG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AACTCATCATAAATGACGTCTTTTACCGAG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATAGTTCGACGAAAAAGCCGAAAGAGA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GCGGCCACGACCGCCATGGGTGTCAGCGCC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TCGGATAACTTAGCGGCGGCGTATCCCTGC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTACCGGGTGTTAAATCTGAATTAGAAGCGCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTCATCAACATTTTCATCAACGCGACTAGTTGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACATAGTGACAGCATCTGTTTTCGGACCAATCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGAGGCTTGCACTAGTGAGTTCAATCGTTATGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTGTCCATACGAGCAGCGTTGGCACTTATTCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTATTATTATCAACGTCCCGCATTGCGTTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AGGATATATGAAATTAGTACATGTACTAGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ACGTCTTTCAGCCCAGTAAACTGCTCAAGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTTGAATACCATTCCTTGTTTATACTCCATCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACCAATACCATAGTAGTCAATTATTACACGTCGTCTTGAATAGTAGTCAATTATTACACGTCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGTGACGTGCTCCCATGTGACCCGAATTGACGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CGACTCTAATGGATATTTTCAATCATAGCA
GTCTTGAATAGTAGTCATATCAAATAGGTTTAGAAC	GATGGTGCTGTTGCACGTGATCCCGCGCTT


>NZ_CP028261|2|3|2831785-2831952|PILER-CR
	AAAATGGATTTCTGAGCATTACTGTCCGAC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GACTATACCAATGAGGTCGAAGCATGGTTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTTTTTAGCAGATTTAATGAATTCGTCATC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TAGGTTTACTCATGGTAAATCCTCCTATGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATAAATTTAAGGTTGCGCAACACAATG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AACTCATCATAAATGACGTCTTTTACCGAG
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AAAATAGTTCGACGAAAAAGCCGAAAGAGA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GCGGCCACGACCGCCATGGGTGTCAGCGCC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	TCGGATAACTTAGCGGCGGCGTATCCCTGC
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTACCGGGTGTTAAATCTGAATTAGAAGCGCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTCATCAACATTTTCATCAACGCGACTAGTTGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACATAGTGACAGCATCTGTTTTCGGACCAATCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGAGGCTTGCACTAGTGAGTTCAATCGTTATGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTGTCCATACGAGCAGCGTTGGCACTTATTCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	GTATTATTATCAACGTCCCGCATTGCGTTA
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	AGGATATATGAAATTAGTACATGTACTAGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	ACGTCTTTCAGCCCAGTAAACTGCTCAAGT
GTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACTTGAATACCATTCCTTGTTTATACTCCATCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACCAATACCATAGTAGTCAATTATTACACGTCGTCTTGAATAGTAGTCAATTATTACACGTCGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAACGTGACGTGCTCCCATGTGACCCGAATTGACGTCTTGAATAGTAGTCATATCAAACAGGTTTAGAAC	CGACTCTAATGGATATTTTCAATCATAGCA
GTCTTGAATAGTAGTCATATCAAATAGGTTTAGAAC	GATGGTGCTGTTGCACGTGATCCCGCGCTT
GTCTTGAATAGTAGTCATATCAAGCAGGTTTAGAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP028261.1\|WP_003641724.1\|2818733_2819204_-\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|240033
NZ_CP028261.1\|WP_063722120.1\|2822683_2823391_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP028261.1\|WP_063721935.1\|2817025_2818618_+\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|214906
NZ_CP028261.1\|WP_003641725.1\|2819436_2820801_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|182694
NZ_CP028261.1\|WP_063722123.1\|2829430_2829736_+\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0206_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|226043
NZ_CP028261.1\|WP_063722125.1\|2835104_2835863_+\|nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|350158
NZ_CP028261.1\|WP_003641738.1\|2840732_2841926_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340897
NZ_CP028261.1\|WP_160257322.1\|2820758_2822453_-\|IS1182-family-transposase	unknown	unknown	gnl\|CDD\|376573
NZ_CP028261.1\|WP_003643664.1\|2840302_2840668_+\|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP028261.1\|WP_003641733.1\|2837500_2837923_+\|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl\|CDD\|107228
NZ_CP028261.1\|WP_003646321.1\|2836881_2837355_+\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP028261.1\|WP_063722121.1\|2823415_2824198_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP028261.1\|WP_063722126.1\|2836165_2836768_-\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|377026
NZ_CP028261.1\|WP_011100889.1\|2816042_2816783_+\|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|224982
NZ_CP028261.1\|WP_003641730.1\|2835905_2836100_-\|PspC-domain-containing-protein	unknown	unknown	gnl\|CDD\|377200
NZ_CP028261.1\|WP_063722124.1\|2829732_2830410_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd12218_csn2_CAS-II-A	gnl\|CDD\|213411
NZ_CP028261.1\|WP_063722127.1\|2842169_2843018_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381297
NZ_CP028261.1\|WP_003643663.1\|2839045_2840278_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340949
NZ_CP028261.1\|WP_045351420.1\|2832081_2834820_-\|cation-transporting-P-type-ATPase	unknown	unknown	gnl\|CDD\|319775
NZ_CP028261.1\|WP_060684251.1\|2828547_2829453_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851

Protein	Function_ID	Function_description	E-value
NZ_CP028261.1\|WP_003641724.1\|2818733_2819204_-\|NUDIX-hydrolase	gnl\|CDD\|240033	cd04677, Nudix_Hydrolase_18, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	8.22877e-58
NZ_CP028261.1\|WP_063721935.1\|2817025_2818618_+\|DNA-binding-protein	gnl\|CDD\|214906	smart00910, HIRAN, The HIRAN protein (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p. HIRAN is found as a standalone protein in several bacteria and prophages, or fused to other catalytic domains, such as a nuclease of the restriction endonuclease fold and TDP1-like DNA phosphoesterases, in the eukaryotes. It has been predicted that this protein functions as a DNA-binding domain that probably recognises features associated with damaged DNA or stalled replication forks.	2.11625e-17
NZ_CP028261.1\|WP_003641725.1\|2819436_2820801_+\|amino-acid-permease	gnl\|CDD\|182694	PRK10746, PRK10746, putative transport protein YifK; Provisional.	0
NZ_CP028261.1\|WP_063722123.1\|2829430_2829736_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.86227e-25
NZ_CP028261.1\|WP_063722125.1\|2835104_2835863_+\|nucleoside-phosphorylase	gnl\|CDD\|350158	cd09007, NP-I_spr0068, uncharacterized subfamily of the nucleoside phosphorylase-I family. This subfamily is composed of uncharacterized members including Streptococcus pneumoniae hypothetical protein spr0068. The nucleoside phosphorylase-I (NP-I) family members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases such as purine nucleoside phosphorylase (PNP, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases such as AMP nucleosidase (AMN, EC 3.2.2.4) and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). Members of the NP-I family display different physiologically relevant quaternary structures: hexameric (trimer-of-dimers arrangement of Shewanella oneidensis MR-1 UP); homotrimeric (human PNP and Escherichia coli PNPII or XapA); hexameric (with some evidence for co-existence of a trimeric form) such as E. coli PNPI (DeoD); or homodimeric such as human and Trypanosoma brucei UP. The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	1.48358e-89
NZ_CP028261.1\|WP_003641738.1\|2840732_2841926_+\|MFS-transporter	gnl\|CDD\|340897	cd17339, MFS_NIMT_CynX_like, 2-nitroimidazole and cyanate transporters and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Escherichia coli 2-nitroimidazole transporter (NIMT) and cyanate transport protein CynX, and similar proteins. NIMT, also called YeaN, confers resistance to 2-nitroimidazole, the antibacterial and antifungal antibiotic, by mediating the active efflux of this compound. CynX is part of an active transport system that transports exogenous cyanate into E. coli cells. The NIMT/CynX-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.6578e-118
NZ_CP028261.1\|WP_160257322.1\|2820758_2822453_-\|IS1182-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	1.02612e-14
NZ_CP028261.1\|WP_003643664.1\|2840302_2840668_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	7.3086e-14
NZ_CP028261.1\|WP_003641733.1\|2837500_2837923_+\|Hsp20/alpha-crystallin-family-protein	gnl\|CDD\|107228	cd06471, ACD_LpsHSP_like, Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and are generally active as large oligomers consisting of multiple subunits. Transcription of the genes encoding Lp HSP 18.5, 18.55 and 19.3 is regulated by a variety of stresses including heat, cold and ethanol. Early growing L. plantarum cells contain elevated levels of these mRNAs which rapidly fall of as the cells enter stationary phase. Also belonging to this group is Bifidobacterium breve (Bb) HSP20 and Oenococcus oenis (syn. Leuconostoc oenos) (Oo) HSP18. Transcription of the gene encoding BbHSP20 is strongly induced following heat or osmotic shock, and that of the gene encoding OoHSP18 following heat, ethanol or acid shock. OoHSP18 is peripherally associated with the cytoplasmic membrane.	2.47416e-43
NZ_CP028261.1\|WP_003646321.1\|2836881_2837355_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	0.000122978
NZ_CP028261.1\|WP_063722121.1\|2823415_2824198_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	2.17929e-25
NZ_CP028261.1\|WP_063722126.1\|2836165_2836768_-\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|377026	pfam03358, FMN_red, NADPH-dependent FMN reductase.	2.80954e-31
NZ_CP028261.1\|WP_011100889.1\|2816042_2816783_+\|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	gnl\|CDD\|224982	COG2071, COG2071, Predicted glutamine amidotransferases [General function prediction only].	7.45143e-88
NZ_CP028261.1\|WP_003641730.1\|2835905_2836100_-\|PspC-domain-containing-protein	gnl\|CDD\|377200	pfam04024, PspC, PspC domain. This family includes Phage shock protein C (PspC) that is thought to be a transcriptional regulator. The presumed domain is 60 amino acid residues in length.	2.12668e-17
NZ_CP028261.1\|WP_063722124.1\|2829732_2830410_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213411	cd12218, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	2.3635e-80
NZ_CP028261.1\|WP_063722127.1\|2842169_2843018_+\|aldo/keto-reductase	gnl\|CDD\|381297	cd19071, AKR_AKR1-5-like, AKR1/2/3/4/5 family of aldo-keto reductase (AKR) and similar proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. The family includes AKR1A/B/C/D/E/G/I, AKR2A/B/C/D/E, AKR3A/B/C/D/E/G, AKR4A/B/C, AKR5A/B/C/D/E/F/G/H, and similar proteins.	2.6134e-121
NZ_CP028261.1\|WP_003643663.1\|2839045_2840278_+\|MFS-transporter	gnl\|CDD\|340949	cd17391, MFS_MdtG_MDR_like, Multidrug resistance protein MdtG and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli multidrug resistance protein MdtG, Streptococcus pneumoniae multidrug resistance efflux pump PmrA, and similar multidrug resistance (MDR) transporters from bacteria. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtG confers resistance to fosfomycin and deoxycholate. PmrA serves as an efflux pump for various substrates and is associated with fluoroquinolone resistance. MdtG-like MDR transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.1962e-140
NZ_CP028261.1\|WP_045351420.1\|2832081_2834820_-\|cation-transporting-P-type-ATPase	gnl\|CDD\|319775	cd02080, P-type_ATPase_cation, P-type cation-transporting ATPase similar to Exiguobacterium aurantiacum Mna, an Na(+)-ATPase, and Synechocystis sp. PCC 6803 PMA1, a putative Ca(2+)-ATPase. This subfamily includes the P-type Na(+)-ATPase of an alkaliphilic bacterium Exiguobacterium aurantiacum Mna and cyanobacterium Synechocystis sp. PCC 6803 PMA1, a cation-transporting ATPase which may translocate calcium. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP028261.1\|WP_060684251.1\|2828547_2829453_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.76066e-89

>NZ_CP028261.1|WP_063722124.1|2829732_2830410_+|type-II-A-CRISPR-associated-protein-Csn2
MNITYYPFPPFKIDAGKVNVLDLGNSNMYAEVCQGFRDRIDSVRISNDDLELQTMSSQCNWYGDLMLSVDLNRLFLKKVQTQIIKLMADDRQVAVLDENRKVVSQVMEASFLLDLPLDVDESPSLEQILKFTGIHFPTELMNDPRAILEALVQTHVELGLKQKLVLTNISHYLDQKQWASFEQLVHDLGATVIVIEYSEINRMEKFKNSCYYYVDEDLVDWRDMN
>NZ_CP028261.1|WP_063722123.1|2829430_2829736_+|CRISPR-associated-endonuclease-Cas2
MRLIVMFDVPMDTSEERRAYRHFHKALVREGFLMMQYSTYVRVCVNKKAAEFVEKRIAPLAPKGGKVQTMTVTEKQYQAMHYIQGTPSNDVLNSAERTIVI
>NZ_CP028261.1|WP_060684251.1|2828547_2829453_+|type-II-CRISPR-associated-endonuclease-Cas1
MGWRNVIITQHAKVSYSMNRILVQTSSDKYAVPISDIQLLLVGTTQAVITSAALCALAEAHVKVIFTDHQGEPISETNDYYPTRRTADLVRQQVTWPEARIATLWTKNVGSKILNQIQVIDFVGGDTQTLVDELDKLELNDVTNREAVVANKYFSLLFGDQFYRRDFSPINAALNYGYAVLLSMVNREIVLNGYLTCIGIHHENNENEFNLGSDLMEPFRPIVDQWVSQQRFKDFTPDIKIGLVSLLDLEIGFNGHQTIVSHAITEYVAACLHYLSGETEELKIEVKLPDEVSSDAINSHV
>NZ_CP028261.1|WP_063722121.1|2823415_2824198_+|alpha/beta-hydrolase
MHFITSDHVQLDYTDEGQGQPIVILTGFGGAKDIWRAQIPVLIQAGYRVINLDGRCQGLSEHTAKGLRMSRRAVDAHELIEKLQLEQPILLGNSMGAATWFAYVSLYGDTGIKALIDVDQTPQMINTPHWQYGFKQVQWQDIPDYFRMPLGHSTFKHIDDATYARVKAVEAQAPFDAKLMFPLLVNHAVQDWRDVIRQLTVPFLIIAGAKSPFFNPDFAAVTAQMALRGQSVVIPEAGHIVMAEQSAAFNKALLEFLATC
>NZ_CP028261.1|WP_063722120.1|2822683_2823391_+|hypothetical-protein
MVKQGHYAKVSKQKRLRQLKQRRQAQEKRAIMPEMVSEFLQVRYHLTQAAKQRPAMRQMMQRFMAQWLAAGQAELSDNGQTTWSVVALTKQTLQTFNRQLPWQGYALVDQEMARWTAFLNKEVPAVPLSERITLTEALSPATWQACLSEQLAVNALLALTGDSRQLSQITTEQVRQLQTSIQTATGIDWEKVAQLLDSTVIAQNTLSEAEPDDKTRQWLEKLQKLTPQDFNNHVE
>NZ_CP028261.1|WP_160257322.1|2820758_2822453_-|IS1182-family-transposase
MQDYYNMNQTTLSIALDYQPEEHHPARYINQLVESLKLKYDYQFGRPREYNLGAMLKLVLLAYCYGIFSSRKIEQFARENKPAGWLIADQIPSYRTICRFRISDELATLTTDSLSQLTQYLRQNGMIDDVSFIDGTKILADANKYSFVWKKNTIRFDKMNREKLVDLLGELHEAKIVGEIPAGSELTPELLDIMISKVEDHLVVLNETVEATKQVSPNPAKQQRRTVKSQKRKLNKRRDKMREHQAQQAIYGQRNSYSKTDHDATFMRVKEDPMQNGQLKPAYNVQIATSNQFITGYRLFQNPTDTRTLQPFIERLKANNVLGHTIVADAGYGSESNYRYLEDEFGQHTVLIPYGTMLKENSRKWQSDDRKVMNWDYHEKDDYFINPQNVRFNFNAYRQRTDKYGFTRDFKEYIAEKYDENHQLIAAALTPKGYLKRISVNENWEYFKSKQRELLSAPETGQIYAQRKIDVEPVFGKMKASLHFNRFSVRGFDKVTKEAGIVILALNIMKLVTVGTNFKNQRRKQMGRETKIRFLVPFAYTEASYVTASLDYNVSSLLPAYLRK
>NZ_CP028261.1|WP_003641725.1|2819436_2820801_+|amino-acid-permease
MQRKLSTGQMQMIALGGTIGVGLFMGSSSTIKWTGPSVLIAYIVSGAFLYLIMRALGEMLYVDPNTGSFAKFASEYIHPVFGYLTAWSNIFQFVVVGMSEMIALGGYCRYWWPNLPDWIPGLIAIVFLCAANLISVKMFGTLETWFSLIKVVTIILMIIAGLGLIIFGIGNGGHPIGISNLWTHGGFFTGGVKGFVFALAIVLASYQGIELIGVTAGEAENPQSTIVKAIRSTVARILIFYVGAIFVIVSIYPWDKLSQIGSPFVQTFAKIGITAAASIINFVVITASLSGTNSGIYSASRMTYTLAESHQLPRKMTLLNRHGVPFYSVIAIATGILIGVVLNVVLPMFFKDASEIFVMVYSSSVLPGMVPWFVILVSQIAFRKQNAAKMANHPFKMPLSPYSNYLTLAFLALTLVFMFINPETRYSILVGVVFLVIMTLIYFRKYAGNKEETL
>NZ_CP028261.1|WP_003641724.1|2818733_2819204_-|NUDIX-hydrolase
MANYIKEIRALVGHKPIILNTAAGILVNDQQQVLLNLRTDTHNWSLPGGYLEYGETYATACVREYKEDSGIDVEVVDRIGIFDKGETAYPNGDVAQTISALFLVKPIGGHVLTQATDETLKLDYFDFDNLPPLLNQQNADMIHAAQEYLQTHSATK
>NZ_CP028261.1|WP_063721935.1|2817025_2818618_+|DNA-binding-protein
MERIEAGMSVMTLKKQTYRVIAVINQGQELLVRAHEPETADIEIIPVTTVVQVTEQNSTDDAAVALDTVTVVGERYVDDIVATLTTLRVGMAVLLQRESGNQYDDNAISVWTLQHAKLGYIARYQNQPYATLMDQGQRLYGIVTVLDQQKQHLELMLWRTTAVPSPIEALQIRQRLAKPRTNLGAVPTHSLQTPLGTIVMMCNGHPIKYQQVPLSPWLTPADELHVTKRYLLTPDWSQVPPDSLITCQVTAKADVVQRWQNEHISAAVLTNASSFYVVGISAQTKTGLNDNLVDDVAQPAVIYRVGQVSAHMQAGFMVSWAPFGDPRVQPALKLALHFSSQPLVLYHPVTPSRTNATFTQQELAALLVSALPNYQGGQRLEPSVTAITVEKLRQTLGDQTYHALANYQRHVQLVAGSTEGVNETLLQALIHAVTYHELTTMHYYQPTVGMVDQVIYPIQLFSTTTKDEDDAQLVGCLALYNYETFEIQQVPLTAIARIAIIADPEHPQTTPETESPDWLRIFLHGWNDDF
>NZ_CP028261.1|WP_011100889.1|2816042_2816783_+|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein
MVKPIIGIAPGVVTVNSQMFPGRVRDYVNRDYLKSVTDNGGVPLVLPVTTDATTIERYVGMIDGLLLCGGADVAPLTYGEEPQPKLGGVDPERDQYEIALIRATHAVGKPVLGICRGLQILNVCYGGNLYQDMSELPAGQGTLKHMQGQLAAYGMHHVKVVPGTTLAEYLGTTSDAIAINSFHHQAVKQVATGFQVVAQSADQVVEAIEATAGGLQLGVQWHPEMMQQVNSMQARLFAAFVRACVA
>NZ_CP028261.1|WP_045351420.1|2832081_2834820_-|cation-transporting-P-type-ATPase
MIKDDNQSLTSNEEQNDTQNPPDADNLWQLDESALAAKYATDPENGLSTAEAAERLQHNGRNELETKRTSRFVQFIKQFNNSIIYILAAAAVLTFFMHHYSDSIVIGLVIIANAIIGYVQERQAGNALERIREMLISKNFVIRDGKKLEIDARELVVGDLVNLEAGDAVPADMRLISADNFNVQESVLTGETNPVEKQEEPMTETTPALADRKNMVYASTAVTSGSAVGIVTATAEDTEIGHIQQSVSDVKQTTTPLMRNLNSLGFGLSIAIVVAAVLLFLLGMVMDTYSLPTLLIAVITMVVGSMPEGLPASTSVVLAMGTRQMTKKNVIVKSLPAVETLGAVDIVNTDKTGTLTKNEMTVTKVVTPEHTFDVTGVGYDDNGGVNFDGHLKLNGNKVDWHQDNAMEWLVKIAGQTTDAELHFENNRWELTGEPTDGALTTLYRKMTGHDPEVEEVDSLPFDSAFRFSARLADLDGQRLLMVKGSPATVLRLTDQANQTAYWDDAMDDLTADGLRVVALAYQEVDDDVTTIDAQAIGGLHLAGLVGIIDPPREEAATAIAELRQAGVQVKMITGDHPDTAMAIANKLNLAANVKAITGPEIDAMDDQQLQAHIDDYNVFARATPNNKLRIVRAQQANNHVVSMTGDGVNDAPALKQADIGVAMGIKGTEVAKESADMVLADDDFADIVAAVREGRHVFDNIRKTIRFLLPTSFAEGLVVIISILMGHELPLYPTQLLWINMVSALTIQFAFIFEPPEAGIMARGPRNVKSGLLSKLDYFEIGYVSFLISGLGIFAYNYLTALGLPNVVGSTMSLNIIIFGKIFYLFNLRNDHPVISKYFFQNKMAFYIIGILILLQLGIIYLPFMQSVFHTTSINFWYGWGIPIICGIVVLIVTEVGKFIRFRWMGKDGVID
>NZ_CP028261.1|WP_063722125.1|2835104_2835863_+|nucleoside-phosphorylase
MTDKLTLLQYDPNPTAMVGPDVDGRFTVPAKLLYIFSGDDYFQQFVTRYHGHRLGQFNTITKVSWVYQIGYRGQKLAVAQAPLGSPAATMYLEMLIDFGARTVIAVGSCGALTALPEEQLLIPTVALRDEGTSFHYLAAADWVPLDPRVIQVLGTTLTKACLPWQMVKTWTTDAFFRETVSKVKAARQQGCQVVEMECSALAACSAFRQVSFGQLLYTADTLAQLEHYDPRHWGAGGVLVAIELATESLAAY
>NZ_CP028261.1|WP_003641730.1|2835905_2836100_-|PspC-domain-containing-protein
MKIDIHRSATDRVIAGVIGGIAEHFNWNTNVTRLLFVVLAITPMFPGIIAYLILWLLMKDPIKD
>NZ_CP028261.1|WP_063722126.1|2836165_2836768_-|NAD(P)H-dependent-oxidoreductase
MFKIAIILGSTRSQANGRALFNHLKLIIDQLPTHSTIHYQFLDLANYQLPLFDEPEPPMANPHRELPANQQQWLTDMASADGYIILTPEYNHAMPAGLKNAFDFLAFEGARKPAKIISYSDNMRGGQFGAAALVPVLQRLGMVVLPKPTPIGNVPQTLQSNGHFIDNAPLSKRYDRALHQALTEITYYTTVLTTTPFPTD
>NZ_CP028261.1|WP_003646321.1|2836881_2837355_+|winged-helix-turn-helix-transcriptional-regulator
MTTPLVSQLMTELNQFLTQDSVDDQEKRWAMQQTTDPQLQAALKQLSTTDIKIIAYLGRRGASRAKSLPAPTELSQATISRGLTKLSRLKLATKYRDLTNNKEILVRLTTLGEAVADLHTQLDAAIAAKAQAIADDYSDAELRRFVSLMRRIREIKI
>NZ_CP028261.1|WP_003641733.1|2837500_2837923_+|Hsp20/alpha-crystallin-family-protein
MANTLMNRNDFGMLDPFERMARSFWAPLENMDQVLKTDINETDDQYQVKVDVPGIDKQDVKLDYRDNVLSIKVQKDSFVDHEDQDQNIVMNERHTGTLQRQYMLPNVAADKITASQADGVLTITLPKTQPSANDGQIEIQ
>NZ_CP028261.1|WP_003643663.1|2839045_2840278_+|MFS-transporter
MDDAERERGPWHRNLIVLWFCTFVAGMAFSEIMPFLSLFVSQLGDFTKAQITFYSGLAFAADYAISAISAPLWGIIADKKGRKIMLLRASLGMAVAMGLMGFVTNVWQLVALRALQGVFAGFISNAQALVASQTPRKYSGRALSTLITGAVSGQLFGPVIGGLLAQLFSIRNTFFITAGLLMVAFLLSLFFVQEHFKPVAHHREPGDSRNPLAAFQNPRLIIVMLCSTAIVQFGNASIAPIISLYVRELMHYRGPITVVAGIIAALPGISNIFSAPRLGRYGDQHGSGKVLLFGYIFAVIMYFPQGIVTSVVALGILRFAIGISDGALYPEIQTVLTKNTPVHLTSTIFSYNQSFQAIGNMFGALLGGLVAGWFNYNAVFIMTALLLLINLGLILWLVPDIWKNGKRAVS
>NZ_CP028261.1|WP_003643664.1|2840302_2840668_+|winged-helix-turn-helix-transcriptional-regulator
MASCLFCYLSLNMMLIQCIVSFMNIEISKQDQADQQRVAIFKALADANRLRIIRVLYQAQREMTCSEVGAQLNISKSTVSYHFKTLRLVGLTNTRRKAQTKYLSLQLATFDRFLPGFLATL
>NZ_CP028261.1|WP_003641738.1|2840732_2841926_+|MFS-transporter
MTTTHQHSRYLTLGMMLAATNMRLPITMMPGLISSLKRTLGLPSSMAGLLTTIPLLTFAIMSPLIAHWGRRFGNELTIYVMLIFLAVGSYLRVIPTIAALFIGTLLVGIGADGGNVLIPAIIKDNFPTKIPVATSQYTLSMLLVGSLGTGLSGVLAAHWSLPLTMAVLSVIGLINLVVWLPNLKYNHRAPTVAMTASDGQSTATHGSVWRRPLAWVVTAFFGLQALVYYSLLTWLPTVFVAHGFSLIVAGNLVTVMQLSGLPMSYLVPATSGHRRGVWAMIMVVGVGFIAGIGGILLSGTNFWVAALSCVLLGLGSGAAFSLAVVFFTQKTTNGFETADLSGMAQSAGYLLAAVGPVLFGWLGGQLGWGPVLWLAIILSALLALSGSIIFQHATIYE
>NZ_CP028261.1|WP_063722127.1|2842169_2843018_+|aldo/keto-reductase
MTVLTTMYQLANGVNIPKVAFGTWQIPGGEATYQAVRAALAAGYRHIDTALAYQNEASVGQAIRDSGIPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAPWPWGQVGRVYDEANLDVWQAMEAIYQSGRAKAIGVSNFAVRDLKNILNQATIPPMVNQIQYYLGFTEPKITKFSEEHAMLVEAYSPLATGGVLDNPQVQAYADKYGVSVAQLALRFVLQNGVLPLPKAVNPAHIEANTQLDFAISVADMQALNDLPDAAGSYMHNLTQG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP028261_2	2.17\|2831527\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT,PILER-CR	2831527-2831556	30	NC_004305	Lactobacillus phage phig1e, complete genome	33581-33610	0	1.0
NZ_CP028261_2	2.17\|2831527\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT,PILER-CR	2831527-2831556	30	X98106	Lactobacillus bacteriophage phig1e complete genomic DNA	33581-33610	0	1.0
NZ_CP028261_2	2.12\|2831197\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT	2831197-2831226	30	NZ_CP025993	Lactobacillus plantarum subsp. plantarum strain LB1-2 plasmid pLB1-2B, complete sequence	35085-35114	1	0.967
NZ_CP028261_2	2.18\|2831593\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT	2831593-2831622	30	JX486087	Lactobacillus phage ATCC 8014-B1, complete genome	30242-30271	3	0.9
NZ_CP028261_2	2.8\|2830933\|30\|NZ_CP028261\|PILER-CR,CRISPRCasFinder,CRT,CRT	2830933-2830962	30	JX486087	Lactobacillus phage ATCC 8014-B1, complete genome	8954-8983	4	0.867
NZ_CP028261_2	2.18\|2831593\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT	2831593-2831622	30	JN051154	Pediococcus phage clP1, complete genome	15025-15054	4	0.867
NZ_CP028261_2	2.17\|2831527\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT,PILER-CR	2831527-2831556	30	AY682195	Lactobacillus plantarum bacteriophage LP65, complete genome	7535-7564	5	0.833
NZ_CP028261_2	2.17\|2831527\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT,PILER-CR	2831527-2831556	30	NC_006565	Lactobacillus phage LP65, complete genome	7535-7564	5	0.833
NZ_CP028261_2	2.17\|2831527\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT,PILER-CR	2831527-2831556	30	NZ_CP014913	Lactobacillus paracollinoides strain TMW 1.1979 plasmid pL11979-1, complete sequence	43852-43881	5	0.833
NZ_CP028261_2	2.17\|2831527\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT,PILER-CR	2831527-2831556	30	NZ_CP014925	Lactobacillus paracollinoides strain TMW 1.1995 plasmid pL11995-1, complete sequence	1277-1306	5	0.833
NZ_CP028261_2	2.17\|2831527\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT,PILER-CR	2831527-2831556	30	KU052488	Lactobacillus phage SA-C12, complete genome	48107-48136	5	0.833
NZ_CP028261_2	2.13\|2831263\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT	2831263-2831292	30	MN119376	Streptomyces phage Geostin, complete genome	10843-10872	6	0.8
NZ_CP028261_2	2.13\|2831263\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT	2831263-2831292	30	MH155868	Streptomyces phage FlowerPower, complete genome	10843-10872	6	0.8
NZ_CP028261_2	2.13\|2831263\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT	2831263-2831292	30	MN284894	Streptomyces phage Fabian, complete genome	10843-10872	6	0.8
NZ_CP028261_2	2.1\|2830471\|30\|NZ_CP028261\|PILER-CR,CRISPRCasFinder,CRT,CRT	2830471-2830500	30	KX961630	Bacillus phage QCM8, complete genome	50060-50089	7	0.767
NZ_CP028261_2	2.4\|2830669\|30\|NZ_CP028261\|PILER-CR,CRISPRCasFinder,CRT,CRT	2830669-2830698	30	KX507046	Vibrio phage S4-7, complete genome	56857-56886	7	0.767
NZ_CP028261_2	2.10\|2831065\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT	2831065-2831094	30	MK560763	Virgibacillus phage Mimir87, complete genome	8629-8658	7	0.767
NZ_CP028261_2	2.16\|2831461\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT,PILER-CR	2831461-2831490	30	LR215721	Staphylococcus phage Stab22 genome assembly, chromosome: I	2364-2393	7	0.767
NZ_CP028261_2	2.16\|2831461\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT,PILER-CR	2831461-2831490	30	LR215721	Staphylococcus phage Stab22 genome assembly, chromosome: I	144638-144667	7	0.767
NZ_CP028261_2	2.22\|2831887\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,PILER-CR	2831887-2831916	30	NZ_CP015089	Pelagibaca abyssi strain JLT2014 plasmid pPABY5, complete sequence	37190-37219	7	0.767
NZ_CP028261_2	2.23\|2831659\|30\|NZ_CP028261\|CRT	2831659-2831688	30	NZ_CP024791	Nostoc flagelliforme CCNUN1 plasmid pNFSY06, complete sequence	197362-197391	7	0.767
NZ_CP028261_2	2.23\|2831659\|30\|NZ_CP028261\|CRT	2831659-2831688	30	NZ_CP015007	Aminobacter aminovorans strain KCTC 2477 plasmid pAA02, complete sequence	122733-122762	7	0.767
NZ_CP028261_2	2.1\|2830471\|30\|NZ_CP028261\|PILER-CR,CRISPRCasFinder,CRT,CRT	2830471-2830500	30	MN013089	Bacillus phage vB_BspM_MarvelLand, complete genome	137765-137794	8	0.733
NZ_CP028261_2	2.1\|2830471\|30\|NZ_CP028261\|PILER-CR,CRISPRCasFinder,CRT,CRT	2830471-2830500	30	MH688040	Salmonella phage Mooltan, complete genome	70183-70212	8	0.733
NZ_CP028261_2	2.1\|2830471\|30\|NZ_CP028261\|PILER-CR,CRISPRCasFinder,CRT,CRT	2830471-2830500	30	NC_025446	Escherichia phage ECML-4, complete genome	125647-125676	8	0.733
NZ_CP028261_2	2.1\|2830471\|30\|NZ_CP028261\|PILER-CR,CRISPRCasFinder,CRT,CRT	2830471-2830500	30	MN342150	Escherichia phage vB_EcoM_3HA11, complete genome	38164-38193	8	0.733
NZ_CP028261_2	2.1\|2830471\|30\|NZ_CP028261\|PILER-CR,CRISPRCasFinder,CRT,CRT	2830471-2830500	30	NC_023856	Salmonella phage vB_SalM_SJ2, complete genome	146281-146310	8	0.733
NZ_CP028261_2	2.1\|2830471\|30\|NZ_CP028261\|PILER-CR,CRISPRCasFinder,CRT,CRT	2830471-2830500	30	MH427377	Escherichia phage vB_EcoM Sa157lw, complete genome	38644-38673	8	0.733
NZ_CP028261_2	2.1\|2830471\|30\|NZ_CP028261\|PILER-CR,CRISPRCasFinder,CRT,CRT	2830471-2830500	30	FQ312032	Salmonella phage Vi01 complete sequence	90217-90246	8	0.733
NZ_CP028261_2	2.1\|2830471\|30\|NZ_CP028261\|PILER-CR,CRISPRCasFinder,CRT,CRT	2830471-2830500	30	NC_015296	Salmonella phage Vi01, complete genome	90217-90246	8	0.733
NZ_CP028261_2	2.1\|2830471\|30\|NZ_CP028261\|PILER-CR,CRISPRCasFinder,CRT,CRT	2830471-2830500	30	MN066127	Salmonella phage Matapan, complete genome	70171-70200	8	0.733
NZ_CP028261_2	2.2\|2830537\|30\|NZ_CP028261\|PILER-CR,CRISPRCasFinder,CRT,CRT	2830537-2830566	30	NC_004349	Shewanella oneidensis MR-1 megaplasmid, complete sequence	34495-34524	8	0.733
NZ_CP028261_2	2.8\|2830933\|30\|NZ_CP028261\|PILER-CR,CRISPRCasFinder,CRT,CRT	2830933-2830962	30	KM879463	Arthrobacter phage vB_ArtM-ArV1, complete genome	15860-15889	8	0.733
NZ_CP028261_2	2.11\|2831131\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT	2831131-2831160	30	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	984312-984341	8	0.733
NZ_CP028261_2	2.11\|2831131\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT	2831131-2831160	30	MK496767	Capybara microvirus Cap3_SP_332, complete genome	4672-4701	8	0.733
NZ_CP028261_2	2.17\|2831527\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT,PILER-CR	2831527-2831556	30	MT104467	Pseudomonas phage MR4, complete genome	6493-6522	8	0.733
NZ_CP028261_2	2.17\|2831527\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT,PILER-CR	2831527-2831556	30	NC_047802	Pectobacterium phage PP99, complete genome	9391-9420	8	0.733
NZ_CP028261_2	2.17\|2831527\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT,PILER-CR	2831527-2831556	30	KJ749827	Escherichia phage ECBP5, complete genome	7250-7279	8	0.733
NZ_CP028261_2	2.6\|2830801\|30\|NZ_CP028261\|PILER-CR,CRISPRCasFinder,CRT,CRT	2830801-2830830	30	MN693509	Marine virus AFVG_25M367, complete genome	54175-54204	9	0.7
NZ_CP028261_2	2.6\|2830801\|30\|NZ_CP028261\|PILER-CR,CRISPRCasFinder,CRT,CRT	2830801-2830830	30	NZ_CP012101	Bacillus thuringiensis strain HS18-1 plasmid pHS18-2, complete sequence	20801-20830	9	0.7
NZ_CP028261_2	2.10\|2831065\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT	2831065-2831094	30	NZ_CP029457	Bacillus cereus strain FORC087 plasmid pFORC087.3, complete sequence	66140-66169	9	0.7
NZ_CP028261_2	2.17\|2831527\|30\|NZ_CP028261\|CRISPRCasFinder,CRT,CRT,PILER-CR	2831527-2831556	30	NZ_CP032091	Pseudoalteromonas donghaensis strain HJ51 plasmid unnamed1, complete sequence	270177-270206	9	0.7

1. spacer 2.17|2831527|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT,PILER-CR matches to NC_004305 (Lactobacillus phage phig1e, complete genome) position: , mismatch: 0, identity: 1.0

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
acgtctttcagcccagtaaactgctcaagt	Protospacer
******************************

2. spacer 2.17|2831527|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT,PILER-CR matches to X98106 (Lactobacillus bacteriophage phig1e complete genomic DNA) position: , mismatch: 0, identity: 1.0

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
acgtctttcagcccagtaaactgctcaagt	Protospacer
******************************

3. spacer 2.12|2831197|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT matches to NZ_CP025993 (Lactobacillus plantarum subsp. plantarum strain LB1-2 plasmid pLB1-2B, complete sequence) position: , mismatch: 1, identity: 0.967

atagtgacagcatctgttttcggaccaatc	CRISPR spacer
atagtgacagcatctgtttttggaccaatc	Protospacer
********************.*********

4. spacer 2.18|2831593|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT matches to JX486087 (Lactobacillus phage ATCC 8014-B1, complete genome) position: , mismatch: 3, identity: 0.9

ttgaataccattccttgtttatactccatc	CRISPR spacer
gtgaataccataccttgtttataatccatc	Protospacer
 ********** *********** ******

5. spacer 2.8|2830933|30|NZ_CP028261|PILER-CR,CRISPRCasFinder,CRT,CRT matches to JX486087 (Lactobacillus phage ATCC 8014-B1, complete genome) position: , mismatch: 4, identity: 0.867

gcggccacgaccgccatgggtgtcagcgcc	CRISPR spacer
gcggccacgaccgctatgggtgtcagttca	Protospacer
**************.***********. *

6. spacer 2.18|2831593|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT matches to JN051154 (Pediococcus phage clP1, complete genome) position: , mismatch: 4, identity: 0.867

ttgaataccattccttgtttatactccatc	CRISPR spacer
gtaaataccataccttgtttataatccatc	Protospacer
 *.******** *********** ******

7. spacer 2.17|2831527|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT,PILER-CR matches to AY682195 (Lactobacillus plantarum bacteriophage LP65, complete genome) position: , mismatch: 5, identity: 0.833

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
ttgtctttcagcccagtaaactgttcaacg	Protospacer
 .*********************.****

8. spacer 2.17|2831527|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT,PILER-CR matches to NC_006565 (Lactobacillus phage LP65, complete genome) position: , mismatch: 5, identity: 0.833

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
ttgtctttcagcccagtaaactgttcaacg	Protospacer
 .*********************.****

9. spacer 2.17|2831527|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT,PILER-CR matches to NZ_CP014913 (Lactobacillus paracollinoides strain TMW 1.1979 plasmid pL11979-1, complete sequence) position: , mismatch: 5, identity: 0.833

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
acgtctttcaggccggtaaactgctccaaa	Protospacer
*********** **.*********** *.

10. spacer 2.17|2831527|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT,PILER-CR matches to NZ_CP014925 (Lactobacillus paracollinoides strain TMW 1.1995 plasmid pL11995-1, complete sequence) position: , mismatch: 5, identity: 0.833

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
acgtctttcaggccggtaaactgctccaaa	Protospacer
*********** **.*********** *.

11. spacer 2.17|2831527|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT,PILER-CR matches to KU052488 (Lactobacillus phage SA-C12, complete genome) position: , mismatch: 5, identity: 0.833

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
aagtctttcagtccagtaaactgttcaaca	Protospacer
* *********.***********.****

12. spacer 2.13|2831263|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT matches to MN119376 (Streptomyces phage Geostin, complete genome) position: , mismatch: 6, identity: 0.8

gaggcttgcactagtgagttcaatcgttat-	CRISPR spacer
gaggcttggactcgtgagttcaa-caagatg	Protospacer
******** *** ********** *.  **

13. spacer 2.13|2831263|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT matches to MH155868 (Streptomyces phage FlowerPower, complete genome) position: , mismatch: 6, identity: 0.8

gaggcttgcactagtgagttcaatcgttat-	CRISPR spacer
gaggcttggactcgtgagttcaa-caagatg	Protospacer
******** *** ********** *.  **

14. spacer 2.13|2831263|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT matches to MN284894 (Streptomyces phage Fabian, complete genome) position: , mismatch: 6, identity: 0.8

gaggcttgcactagtgagttcaatcgttat-	CRISPR spacer
gaggcttggactcgtgagttcaa-caagatg	Protospacer
******** *** ********** *.  **

15. spacer 2.1|2830471|30|NZ_CP028261|PILER-CR,CRISPRCasFinder,CRT,CRT matches to KX961630 (Bacillus phage QCM8, complete genome) position: , mismatch: 7, identity: 0.767

aaaatggatttctgagcattactgtccgac	CRISPR spacer
taaatggatttctgagcattactacggaaa	Protospacer
 **********************..  .*

16. spacer 2.4|2830669|30|NZ_CP028261|PILER-CR,CRISPRCasFinder,CRT,CRT matches to KX507046 (Vibrio phage S4-7, complete genome) position: , mismatch: 7, identity: 0.767

taggtttactcatggtaaatcctcctatgt	CRISPR spacer
caggtttccacatggtaaatcctctagtgg	Protospacer
.****** * **************. .**

17. spacer 2.10|2831065|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT matches to MK560763 (Virgibacillus phage Mimir87, complete genome) position: , mismatch: 7, identity: 0.767

taccgggtgttaaatctgaattagaagcgc	CRISPR spacer
tgaaagttgttaaatctgaatttgaagcga	Protospacer
*.  .* *************** ******

18. spacer 2.16|2831461|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT,PILER-CR matches to LR215721 (Staphylococcus phage Stab22 genome assembly, chromosome: I) position: , mismatch: 7, identity: 0.767

aggatatatgaaattagtacatgtactagt	CRISPR spacer
attttatatgaaattagtatatgaactcat	Protospacer
*   ***************.*** *** .*

19. spacer 2.16|2831461|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT,PILER-CR matches to LR215721 (Staphylococcus phage Stab22 genome assembly, chromosome: I) position: , mismatch: 7, identity: 0.767

aggatatatgaaattagtacatgtactagt	CRISPR spacer
attttatatgaaattagtatatgaactcat	Protospacer
*   ***************.*** *** .*

20. spacer 2.22|2831887|30|NZ_CP028261|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015089 (Pelagibaca abyssi strain JLT2014 plasmid pPABY5, complete sequence) position: , mismatch: 7, identity: 0.767

gatggtgctgttgcacgtgatcccgcgctt	CRISPR spacer
ctccgagctgttccaggtgatcccgcgctt	Protospacer
  . * ****** ** **************

21. spacer 2.23|2831659|30|NZ_CP028261|CRT matches to NZ_CP024791 (Nostoc flagelliforme CCNUN1 plasmid pNFSY06, complete sequence) position: , mismatch: 7, identity: 0.767

caataccatagtagtcaattattacacgtc	CRISPR spacer
ccataccatcgtattcaattattactttcc	Protospacer
* ******* *** *********** . .*

22. spacer 2.23|2831659|30|NZ_CP028261|CRT matches to NZ_CP015007 (Aminobacter aminovorans strain KCTC 2477 plasmid pAA02, complete sequence) position: , mismatch: 7, identity: 0.767

caataccatagtagtcaattattacacgtc	CRISPR spacer
aaataccatagtcgtcaattatcatatttt	Protospacer
 *********** *********.*.*. *.

23. spacer 2.1|2830471|30|NZ_CP028261|PILER-CR,CRISPRCasFinder,CRT,CRT matches to MN013089 (Bacillus phage vB_BspM_MarvelLand, complete genome) position: , mismatch: 8, identity: 0.733

aaaatggatttctgagcattactgtccgac	CRISPR spacer
taaatggatttccgagcattactacggaaa	Protospacer
 ***********.**********..  .*

24. spacer 2.1|2830471|30|NZ_CP028261|PILER-CR,CRISPRCasFinder,CRT,CRT matches to MH688040 (Salmonella phage Mooltan, complete genome) position: , mismatch: 8, identity: 0.733

aaaatggatttctgagcattactgtccgac	CRISPR spacer
aaaattgatttctgagtattactacatcag	Protospacer
***** **********.******.. . *

25. spacer 2.1|2830471|30|NZ_CP028261|PILER-CR,CRISPRCasFinder,CRT,CRT matches to NC_025446 (Escherichia phage ECML-4, complete genome) position: , mismatch: 8, identity: 0.733

aaaatggatttctgagcattactgtccgac	CRISPR spacer
aaaattgatttctgagtattactacatcag	Protospacer
***** **********.******.. . *

26. spacer 2.1|2830471|30|NZ_CP028261|PILER-CR,CRISPRCasFinder,CRT,CRT matches to MN342150 (Escherichia phage vB_EcoM_3HA11, complete genome) position: , mismatch: 8, identity: 0.733

aaaatggatttctgagcattactgtccgac	CRISPR spacer
aaaattgatttctgagtattactacatcag	Protospacer
***** **********.******.. . *

27. spacer 2.1|2830471|30|NZ_CP028261|PILER-CR,CRISPRCasFinder,CRT,CRT matches to NC_023856 (Salmonella phage vB_SalM_SJ2, complete genome) position: , mismatch: 8, identity: 0.733

aaaatggatttctgagcattactgtccgac	CRISPR spacer
aaaattgatttctgagtattactacatcag	Protospacer
***** **********.******.. . *

28. spacer 2.1|2830471|30|NZ_CP028261|PILER-CR,CRISPRCasFinder,CRT,CRT matches to MH427377 (Escherichia phage vB_EcoM Sa157lw, complete genome) position: , mismatch: 8, identity: 0.733

aaaatggatttctgagcattactgtccgac	CRISPR spacer
aaaattgatttctgagtattactacatcag	Protospacer
***** **********.******.. . *

29. spacer 2.1|2830471|30|NZ_CP028261|PILER-CR,CRISPRCasFinder,CRT,CRT matches to FQ312032 (Salmonella phage Vi01 complete sequence) position: , mismatch: 8, identity: 0.733

aaaatggatttctgagcattactgtccgac	CRISPR spacer
aaaattgatttctgagtattactacatcag	Protospacer
***** **********.******.. . *

30. spacer 2.1|2830471|30|NZ_CP028261|PILER-CR,CRISPRCasFinder,CRT,CRT matches to NC_015296 (Salmonella phage Vi01, complete genome) position: , mismatch: 8, identity: 0.733

aaaatggatttctgagcattactgtccgac	CRISPR spacer
aaaattgatttctgagtattactacatcag	Protospacer
***** **********.******.. . *

31. spacer 2.1|2830471|30|NZ_CP028261|PILER-CR,CRISPRCasFinder,CRT,CRT matches to MN066127 (Salmonella phage Matapan, complete genome) position: , mismatch: 8, identity: 0.733

aaaatggatttctgagcattactgtccgac	CRISPR spacer
aaaattgatttctgagtattactacatcag	Protospacer
***** **********.******.. . *

32. spacer 2.2|2830537|30|NZ_CP028261|PILER-CR,CRISPRCasFinder,CRT,CRT matches to NC_004349 (Shewanella oneidensis MR-1 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.733

gactataccaatgaggtcgaagcatggtta	CRISPR spacer
gactgtaccaatgaggtggaagcgccctgt	Protospacer
****.************ *****..  *

33. spacer 2.8|2830933|30|NZ_CP028261|PILER-CR,CRISPRCasFinder,CRT,CRT matches to KM879463 (Arthrobacter phage vB_ArtM-ArV1, complete genome) position: , mismatch: 8, identity: 0.733

gcggccacgaccgccatgggtgtcagcgcc	CRISPR spacer
ggtttccaaaccgccatgggtgtcagcacc	Protospacer
*   .*  .******************.**

34. spacer 2.11|2831131|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 8, identity: 0.733

tcatcaacattttcatcaacgcgactagtt	CRISPR spacer
tgaaattcattttcatcaacgccactaggc	Protospacer
* *    *************** ***** .

35. spacer 2.11|2831131|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT matches to MK496767 (Capybara microvirus Cap3_SP_332, complete genome) position: , mismatch: 8, identity: 0.733

tcatcaacattttcatcaacgcgactagtt	CRISPR spacer
atatcaaaattttcatcaacgcaacgatac	Protospacer
 .***** **************.** *  .

36. spacer 2.17|2831527|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT,PILER-CR matches to MT104467 (Pseudomonas phage MR4, complete genome) position: , mismatch: 8, identity: 0.733

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
agtgacttcagcccattgaactgctcaagc	Protospacer
*    .********* *.***********.

37. spacer 2.17|2831527|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT,PILER-CR matches to NC_047802 (Pectobacterium phage PP99, complete genome) position: , mismatch: 8, identity: 0.733

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
agtgacttcagcccattgaactgctcaagc	Protospacer
*    .********* *.***********.

38. spacer 2.17|2831527|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT,PILER-CR matches to KJ749827 (Escherichia phage ECBP5, complete genome) position: , mismatch: 8, identity: 0.733

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
agtgacttcagcccattgaactgctcaagc	Protospacer
*    .********* *.***********.

39. spacer 2.6|2830801|30|NZ_CP028261|PILER-CR,CRISPRCasFinder,CRT,CRT matches to MN693509 (Marine virus AFVG_25M367, complete genome) position: , mismatch: 9, identity: 0.7

aactcatcataaatgacgtcttttaccgag	CRISPR spacer
tcatcatcataaacgacttcttttactcct	Protospacer
   **********.*** ********.

40. spacer 2.6|2830801|30|NZ_CP028261|PILER-CR,CRISPRCasFinder,CRT,CRT matches to NZ_CP012101 (Bacillus thuringiensis strain HS18-1 plasmid pHS18-2, complete sequence) position: , mismatch: 9, identity: 0.7

aactcatcataaatgacgtcttttaccgag	CRISPR spacer
tcatcatcataaatggcgtcttttttttat	Protospacer
   ************.******** .. *

41. spacer 2.10|2831065|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT matches to NZ_CP029457 (Bacillus cereus strain FORC087 plasmid pFORC087.3, complete sequence) position: , mismatch: 9, identity: 0.7

taccgggtgttaaatctgaattagaagcgc	CRISPR spacer
ttgatggtgttaaatctcaattagaaaatt	Protospacer
*    ************ ********.  .

42. spacer 2.17|2831527|30|NZ_CP028261|CRISPRCasFinder,CRT,CRT,PILER-CR matches to NZ_CP032091 (Pseudoalteromonas donghaensis strain HJ51 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

acgtctttcagcccagtaaactgctcaagt	CRISPR spacer
ttaaataagagcccaggaaactgctcaagt	Protospacer
 ..  *   ******* *************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

154 : 55083

Lactobacillus_phage(87.88%)

lysis,terminase,portal,tRNA,capsid,protease,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085764169.1\|154_490_+	VRR-NUC domain-containing protein	A0A2P0ZLB6	Lactobacillus_phage	1.7e-58	96.4
WP_160257227.1\|740_899_+	hypothetical protein	A0A2P0ZLB5	Lactobacillus_phage	4.3e-17	88.5
WP_104795781.1\|901_1102_+	hypothetical protein	NA	NA	NA	NA
WP_160257228.1\|1135_1273_+	hypothetical protein	NA	NA	NA	NA
WP_160257229.1\|1275_1710_+	hypothetical protein	Q5ULU9	Lactobacillus_virus	1.1e-67	84.4
WP_160257230.1\|1706_2207_+	DUF1642 domain-containing protein	A0A2K9VC25	Lactobacillus_phage	5.4e-37	53.4
WP_160257231.1\|2333_2645_+	hypothetical protein	A0A2P0ZLD0	Lactobacillus_phage	2.2e-49	94.2
WP_160257232.1\|2656_3088_+	hypothetical protein	A0A2P0ZLC0	Lactobacillus_phage	1.3e-66	93.4
WP_069302382.1\|3257_3473_+	hypothetical protein	A0A2P0ZLC2	Lactobacillus_phage	3.0e-29	87.3
WP_160257233.1\|3456_3795_+	HNH endonuclease	A0A2P0ZLC6	Lactobacillus_phage	3.1e-60	94.6
WP_160257234.1\|3794_4037_+	hypothetical protein	A0A2P0ZLD3	Lactobacillus_phage	1.9e-32	83.8
WP_160257235.1\|4054_4297_+	hypothetical protein	A0A2P0ZLD2	Lactobacillus_phage	2.0e-37	93.8
WP_015380180.1\|4404_4692_+	hypothetical protein	A0A2P0ZLC8	Lactobacillus_phage	2.2e-43	96.8
WP_160257236.1\|4688_6368_+\|terminase	terminase large subunit	A0A2P0ZLE5	Lactobacillus_phage	0.0e+00	98.9
WP_160257237.1\|6386_7529_+\|portal	phage portal protein	A0A2P0ZLC9	Lactobacillus_phage	4.0e-213	97.6
WP_160257238.1\|7515_8268_+\|protease	Clp protease ClpP	A0A2P0ZLE3	Lactobacillus_phage	2.5e-131	97.6
WP_160257239.1\|8288_9467_+\|capsid	phage major capsid protein	A0A2P0ZLD6	Lactobacillus_phage	1.7e-219	99.7
WP_015380185.1\|9605_9911_+	hypothetical protein	A0A2P0ZLD5	Lactobacillus_phage	6.6e-46	94.1
WP_160257345.1\|9891_10281_+	hypothetical protein	A0A2P0ZLD1	Lactobacillus_phage	3.2e-61	86.0
WP_003643908.1\|10277_10685_+	hypothetical protein	A0A2P0ZLD7	Lactobacillus_phage	3.3e-69	97.8
WP_160257240.1\|10681_11104_+	hypothetical protein	A0A2P0ZLE4	Lactobacillus_phage	1.7e-71	97.1
WP_072534051.1\|11118_11730_+\|tail	phage tail protein	A0A2P0ZLF5	Lactobacillus_phage	1.9e-105	97.0
WP_021731063.1\|11822_12137_+	hypothetical protein	A0A2P0ZLF3	Lactobacillus_phage	2.4e-51	96.2
WP_160257241.1\|12400_16996_+\|tail	phage tail tape measure protein	A0A2P0ZLF1	Lactobacillus_phage	0.0e+00	92.5
WP_160257242.1\|16999_17821_+\|tail	phage tail protein	A0A2P0ZLE2	Lactobacillus_phage	1.8e-151	98.2
WP_160257346.1\|18605_22538_+	hypothetical protein	A0A2P0ZLE1	Lactobacillus_phage	1.8e-103	45.3
WP_160257243.1\|22540_22993_+	DUF1617 family protein	A0A2P0ZLE0	Lactobacillus_phage	1.4e-20	39.3
WP_160257244.1\|22992_23439_+	hypothetical protein	A0A2P0ZLE9	Lactobacillus_phage	3.2e-49	73.1
WP_160257245.1\|23443_23827_+	hypothetical protein	A0A2P0ZLF7	Lactobacillus_phage	2.5e-66	96.9
WP_021730687.1\|23829_24024_+	hypothetical protein	A0A2P0ZLG4	Lactobacillus_phage	1.0e-23	96.9
WP_054396940.1\|24023_24308_+\|lysis	lysis protein	A0A2P0ZLE8	Lactobacillus_phage	3.1e-42	98.9
WP_160257246.1\|24307_25240_+	lysin	A0A2P0ZLG2	Lactobacillus_phage	2.4e-171	92.9
WP_003643922.1\|25665_26520_+	hypothetical protein	NA	NA	NA	NA
WP_003640908.1\|26810_27785_+	PTS mannose transporter subunit IIAB	NA	NA	NA	NA
WP_003640909.1\|27820_28627_+	PTS mannose/fructose/sorbose transporter subunit IIC	NA	NA	NA	NA
WP_003640910.1\|28645_29578_+	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
WP_003640911.1\|29706_30093_+	DUF956 family protein	NA	NA	NA	NA
WP_047672753.1\|30399_33249_+	sigma-54-dependent transcriptional regulator	NA	NA	NA	NA
WP_063722271.1\|33319_33739_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_003640914.1\|33735_34254_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_063722272.1\|34417_35389_+	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_003640916.1\|35399_35801_+	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit	NA	NA	NA	NA
WP_015379847.1\|35803_37126_+	acetyl-CoA carboxylase biotin carboxylase subunit	NA	NA	NA	NA
WP_003644983.1\|37122_37926_+	acetyl-CoA carboxylase carboxyltransferase subunit beta	NA	NA	NA	NA
WP_003640919.1\|37918_38692_+	hypothetical protein	NA	NA	NA	NA
WP_003640920.1\|38759_39953_-	LytR family transcriptional regulator	NA	NA	NA	NA
WP_003643925.1\|40262_41225_+	AEC family transporter	NA	NA	NA	NA
WP_003643926.1\|41657_42683_+	EamA family transporter	NA	NA	NA	NA
WP_160257247.1\|42832_43510_+	2,3-diphosphoglycerate-dependent phosphoglycerate mutase	NA	NA	NA	NA
WP_003640924.1\|43928_44621_+\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_003643927.1\|44810_46142_-	C1 family peptidase	R4TV59	Phaeocystis_globosa_virus	5.4e-68	33.3
WP_003640926.1\|46217_46901_-	ribose-5-phosphate isomerase RpiA	NA	NA	NA	NA
WP_003640927.1\|46909_47206_-	N-acetyltransferase	NA	NA	NA	NA
WP_011101073.1\|47344_47881_+	dUTP diphosphatase	J9PV85	Bacillus_phage	1.1e-35	46.4
WP_003643928.1\|49006_50386_+	DNA repair protein RadA	NA	NA	NA	NA
WP_003640931.1\|50401_51577_+	PIN/TRAM domain-containing protein	NA	NA	NA	NA
WP_003640932.1\|51902_53393_+\|tRNA	glutamate--tRNA ligase	NA	NA	NA	NA
WP_160257248.1\|53670_55083_+\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	6.8e-45	29.8

DBSCAN-SWA_2

74604 : 83228

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003644909.1\|74604_76302_+	DNA polymerase III subunit gamma/tau	A0A1U9WR94	Streptococcus_virus	3.9e-55	37.0
WP_003640956.1\|76323_76632_+	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
WP_003637790.1\|76647_77247_+	recombination protein RecR	NA	NA	NA	NA
WP_003640957.1\|77261_77513_+	YaaL family protein	NA	NA	NA	NA
WP_011101140.1\|77910_78576_+	dTMP kinase	M1PSC7	Streptococcus_phage	1.4e-53	52.7
WP_003640965.1\|78572_78902_+	hypothetical protein	NA	NA	NA	NA
WP_063722355.1\|78918_79938_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.1e-32	33.5
WP_003640967.1\|79962_80310_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	2.4e-12	33.3
WP_003643942.1\|80408_81305_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	9.9e-82	55.7
WP_003640969.1\|81308_82094_+	acyl-ACP thioesterase	NA	NA	NA	NA
WP_013355240.1\|82232_83228_+	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	2.0e-51	38.5

DBSCAN-SWA_3

627636 : 696691

Lactobacillus_phage(81.63%)

terminase,integrase,head,portal,holin,tRNA,capsid,protease,tail

attL 633349:633365|attR 675168:675184

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_027822128.1\|627636_628302_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_003644254.1\|628994_629474_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_003643148.1\|629587_630100_-	hypothetical protein	NA	NA	NA	NA
WP_003643147.1\|630214_630502_+	hypothetical protein	NA	NA	NA	NA
WP_027822127.1\|630563_632834_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	8.8e-119	31.5
633349:633365	attL	NA	NA	NA	NA
WP_016058345.1\|633481_634618_-\|integrase	site-specific integrase	E9LUS1	Lactobacillus_phage	9.5e-215	100.0
WP_016058347.1\|635261_635576_-	hypothetical protein	E9LUS3	Lactobacillus_phage	7.7e-50	100.0
WP_016058348.1\|635568_635982_-	hypothetical protein	E9LUS4	Lactobacillus_phage	6.6e-73	100.0
WP_160257263.1\|636308_636509_-	hypothetical protein	E9LUS6	Lactobacillus_phage	6.5e-26	98.5
WP_160257264.1\|636514_637090_-	hypothetical protein	NA	NA	NA	NA
WP_160257265.1\|637214_637886_-	LexA family transcriptional regulator	D7RWL5	Brochothrix_phage	1.7e-41	55.0
WP_027821294.1\|638078_638294_+	helix-turn-helix transcriptional regulator	A0A2H4JBV7	uncultured_Caudovirales_phage	5.9e-17	71.0
WP_160257266.1\|638300_639044_+	hypothetical protein	A0A1P8BM06	Lactococcus_phage	2.0e-51	46.1
WP_160257267.1\|639055_639265_+	hypothetical protein	NA	NA	NA	NA
WP_016058354.1\|639380_639707_-	hypothetical protein	E9LUT2	Lactobacillus_phage	8.3e-55	100.0
WP_016058355.1\|639800_640130_+	DUF771 domain-containing protein	E9LUT3	Lactobacillus_phage	1.1e-59	100.0
WP_016058357.1\|640219_640399_+	helix-turn-helix domain-containing protein	E9LUT5	Lactobacillus_phage	2.2e-25	100.0
WP_016058358.1\|640432_640699_+	hypothetical protein	E9LUT6	Lactobacillus_phage	3.6e-40	100.0
WP_016058359.1\|640701_640902_+	hypothetical protein	E9LUT7	Lactobacillus_phage	1.6e-29	100.0
WP_016058360.1\|640913_641138_+	hypothetical protein	E9LUT8	Lactobacillus_phage	3.8e-35	100.0
WP_102124480.1\|641357_641663_+	hypothetical protein	NA	NA	NA	NA
WP_160257268.1\|641682_642375_+	hypothetical protein	E9LUU3	Lactobacillus_phage	8.9e-107	82.4
WP_160257269.1\|642635_643433_+	replication protein	Q9AZA0	Lactobacillus_prophage	4.2e-52	69.0
WP_064972042.1\|643432_644218_+	ATP-binding protein	E9LUN6	Lactobacillus_phage	1.1e-132	91.6
WP_064972043.1\|644353_644656_+	hypothetical protein	E9LUN7	Lactobacillus_phage	6.1e-44	91.0
WP_063487063.1\|644658_644970_+	hypothetical protein	A0A2P0ZLB4	Lactobacillus_phage	5.0e-49	91.3
WP_063487884.1\|644973_645168_+	hypothetical protein	A0A2P0ZLB7	Lactobacillus_phage	9.1e-17	72.4
WP_127064439.1\|645160_645319_+	hypothetical protein	A0A2P0ZLB5	Lactobacillus_phage	3.3e-17	88.5
WP_063487065.1\|645494_645824_+	hypothetical protein	NA	NA	NA	NA
WP_003644538.1\|646108_646534_+	transcriptional regulator	E9LUP5	Lactobacillus_phage	3.3e-59	77.3
WP_064972044.1\|646856_647768_+	DUF4868 domain-containing protein	A0A1Q1PW39	Staphylococcus_phage	5.4e-11	25.5
WP_080475182.1\|648655_649126_+	HNH endonuclease	E9LUP7	Lactobacillus_phage	1.6e-83	93.6
WP_064972047.1\|649131_649395_+	hypothetical protein	NA	NA	NA	NA
WP_063487069.1\|649412_649664_+	hypothetical protein	NA	NA	NA	NA
WP_044430993.1\|649851_650310_+\|terminase	phage terminase small subunit P27 family	E9LUP8	Lactobacillus_phage	8.0e-80	96.1
WP_044430990.1\|650312_652211_+\|terminase	terminase large subunit	E9LUP9	Lactobacillus_phage	0.0e+00	97.5
WP_044430989.1\|652200_652395_+	DUF1056 family protein	E9LUQ0	Lactobacillus_phage	2.8e-26	95.3
WP_069302494.1\|652397_653591_+\|portal	phage portal protein	E9LUQ1	Lactobacillus_phage	7.9e-220	97.2
WP_069302495.1\|653568_654327_+\|protease	Clp protease ClpP	E9LUQ2	Lactobacillus_phage	6.1e-125	93.3
WP_069302496.1\|654326_655559_+\|capsid	phage major capsid protein	E9LUQ3	Lactobacillus_phage	4.1e-211	92.9
WP_069302497.1\|655631_655970_+\|head,tail	phage gp6-like head-tail connector protein	E9LUQ4	Lactobacillus_phage	7.8e-48	88.4
WP_069302498.1\|655953_656316_+\|head	phage head closure protein	E9LUQ5	Lactobacillus_phage	3.7e-64	97.5
WP_069302499.1\|656305_656746_+\|tail	phage tail protein	E9LUQ6	Lactobacillus_phage	6.5e-79	99.3
WP_069302500.1\|656742_657126_+	hypothetical protein	E9LUQ7	Lactobacillus_phage	2.3e-64	96.9
WP_016058333.1\|657126_657765_+\|tail	major tail protein	E9LUQ8	Lactobacillus_phage	8.8e-117	100.0
WP_046947715.1\|657966_658350_+	hypothetical protein	E9LUQ9	Lactobacillus_phage	1.3e-62	98.4
WP_016058335.1\|658346_658538_+	hypothetical protein	E9LUR0	Lactobacillus_phage	1.5e-27	100.0
WP_069302501.1\|658550_663773_+\|tail	phage tail protein	E9LUR1	Lactobacillus_phage	0.0e+00	78.1
WP_069302502.1\|663844_665617_+\|tail	phage tail protein	E9LUR2	Lactobacillus_phage	0.0e+00	97.1
WP_069302503.1\|665683_668053_+	hypothetical protein	E9LUR3	Lactobacillus_phage	0.0e+00	93.2
WP_160257270.1\|668069_670835_+\|tail	phage tail protein	A0A2P0ZL34	Lactobacillus_phage	2.9e-193	49.7
WP_160257271.1\|670827_671079_+	hypothetical protein	A0A2K9VDF6	Lactobacillus_phage	4.2e-30	97.2
WP_160257272.1\|671871_672450_+	hypothetical protein	A0A2K9V5B0	Lactobacillus_phage	3.5e-16	33.8
WP_160257273.1\|672461_673634_+	LysM peptidoglycan-binding domain-containing protein	E9LUR8	Lactobacillus_phage	1.3e-198	91.8
WP_160257274.1\|673633_673897_+\|holin	holin	E9LUR9	Lactobacillus_phage	1.3e-37	96.6
WP_160257275.1\|673908_674439_+\|holin	holin	E9LUS0	Lactobacillus_phage	8.5e-41	98.9
WP_011101374.1\|675505_675931_-	lipoprotein	NA	NA	NA	NA
675168:675184	attR	NA	NA	NA	NA
WP_003643144.1\|675943_676063_-	hypothetical protein	NA	NA	NA	NA
WP_003644258.1\|676095_677166_-	membrane protein	NA	NA	NA	NA
WP_011101375.1\|677220_677736_+	GtrA family protein	NA	NA	NA	NA
WP_003645248.1\|677835_678195_-	YisL family protein	NA	NA	NA	NA
WP_063722307.1\|678267_680124_-	bifunctional homocysteine S-methyltransferase/methylenetetrahydrofolate reductase	NA	NA	NA	NA
WP_021356309.1\|680137_682444_-	5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase	NA	NA	NA	NA
WP_044430280.1\|684940_686116_+	sulfate adenylyltransferase	A0A2P1ELS9	Moumouvirus	3.8e-49	31.7
WP_003643136.1\|686118_686742_+	adenylyl-sulfate kinase	A0A2K9L4R9	Tupanvirus	6.3e-27	40.6
WP_160257276.1\|686710_687688_+	bifunctional oligoribonuclease/PAP phosphatase NrnA	NA	NA	NA	NA
WP_053566582.1\|687909_689649_+	aryl-sulfate sulfotransferase	NA	NA	NA	NA
WP_024272279.1\|690081_691857_+	SLC13 family permease	NA	NA	NA	NA
WP_003643131.1\|692131_693523_+	MATE family efflux transporter	NA	NA	NA	NA
WP_003643130.1\|693649_693895_+	hypothetical protein	NA	NA	NA	NA
WP_021356340.1\|694284_694731_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_011101383.1\|695002_696691_+\|tRNA	arginine--tRNA ligase	A0A2I2L3K1	Orpheovirus	1.2e-75	32.9

DBSCAN-SWA_4

725278 : 737244

Lactobacillus_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003643099.1\|725278_726226_-	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	2.7e-178	100.0
WP_003643097.1\|726569_727184_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	6.3e-112	100.0
WP_063720948.1\|727186_729625_+	flavocytochrome c	A0A2P0ZL82	Lactobacillus_phage	0.0e+00	99.8
WP_003643095.1\|729712_730273_+	hypothetical protein	A0A2P0ZL75	Lactobacillus_phage	2.7e-101	100.0
WP_003643094.1\|730343_730784_-	nucleoside 2-deoxyribosyltransferase	A0A2P0ZL88	Lactobacillus_phage	8.0e-77	99.3
WP_052098033.1\|731128_731596_+	hypothetical protein	A0A2P0ZL91	Lactobacillus_phage	6.1e-83	99.4
WP_053566592.1\|731570_732545_+	hypothetical protein	A0A2P0ZL95	Lactobacillus_phage	5.0e-31	90.7
WP_047673279.1\|732648_732858_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_003640226.1\|734970_737244_-	HAD-IC family P-type ATPase	M1HX51	Paramecium_bursaria_Chlorella_virus	1.3e-37	23.5

DBSCAN-SWA_5

1215436 : 1276786

Tupanvirus(12.5%)

tRNA,protease,transposase,integrase

attL 1257327:1257344|attR 1283609:1283626

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003644485.1\|1215436_1216591_+\|integrase	site-specific integrase	A0A0A8WIE1	Clostridium_phage	2.5e-98	44.7
WP_160257285.1\|1216707_1218543_-	elongation factor 4	E4ZFJ7	Streptococcus_phage	1.5e-23	26.1
WP_160257286.1\|1218706_1219984_-	D-alanyl-lipoteichoic acid biosynthesis protein DltD	NA	NA	NA	NA
WP_003640705.1\|1219980_1220223_-	D-alanine--poly(phosphoribitol) ligase subunit DltC	NA	NA	NA	NA
WP_003640706.1\|1220246_1221461_-	D-alanyl-lipoteichoic acid biosynthesis protein DltB	A0A125RNP0	Pseudomonas_phage	1.9e-27	30.5
WP_003640707.1\|1221457_1222984_-	D-alanine--poly(phosphoribitol) ligase subunit DltA	A0A2K9KZV5	Tupanvirus	7.6e-42	27.6
WP_003640708.1\|1223026_1223176_-	teichoic acid D-Ala incorporation-associated protein DltX	NA	NA	NA	NA
WP_003645971.1\|1223207_1224383_-	serine hydrolase	NA	NA	NA	NA
WP_003640710.1\|1224816_1225959_-	molecular chaperone DnaJ	A0A2K9L588	Tupanvirus	4.3e-21	32.0
WP_003640711.1\|1226060_1227929_-	molecular chaperone DnaK	A0A2P1EIW2	Megavirus	7.7e-137	47.2
WP_013355604.1\|1227972_1228572_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_003640713.1\|1228592_1229636_-	heat-inducible transcriptional repressor HrcA	NA	NA	NA	NA
WP_003640714.1\|1230026_1230737_-	acetolactate decarboxylase	NA	NA	NA	NA
WP_003640715.1\|1230737_1231739_-	riboflavin biosynthesis protein RibF	NA	NA	NA	NA
WP_003640716.1\|1231751_1232675_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_063722225.1\|1233152_1233674_-	shikimate kinase	NA	NA	NA	NA
WP_063722224.1\|1233676_1234774_-	prephenate dehydrogenase	NA	NA	NA	NA
WP_013355606.1\|1234776_1236075_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_003645964.1\|1236088_1236616_-	amino acid biosynthesis protein	NA	NA	NA	NA
WP_013355607.1\|1236624_1237794_-	chorismate synthase	NA	NA	NA	NA
WP_015825652.1\|1237786_1239241_-	MFS transporter	NA	NA	NA	NA
WP_003640723.1\|1239889_1240243_-	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_024002734.1\|1240265_1242842_-	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	9.6e-21	23.3
WP_063722223.1\|1242856_1243162_-	hypothetical protein	NA	NA	NA	NA
WP_024002733.1\|1243151_1243451_-	YlxR family protein	NA	NA	NA	NA
WP_024002732.1\|1243495_1244713_-	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_063722222.1\|1244733_1245210_-	ribosome maturation factor RimP	NA	NA	NA	NA
WP_003640729.1\|1245505_1249819_-	DNA polymerase III subunit alpha	A0A1X9SH08	Bradyrhizobium_phage	1.0e-14	34.0
WP_003640732.1\|1250312_1252022_-\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_003640733.1\|1252061_1253339_-\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_003640734.1\|1253376_1254162_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_046039550.1\|1254177_1254957_-	isoprenyl transferase	R9W0U9	Flavobacterium_phage	6.9e-23	42.3
WP_003640736.1\|1255076_1255640_-	ribosome recycling factor	NA	NA	NA	NA
WP_003640737.1\|1255641_1256364_-	UMP kinase	NA	NA	NA	NA
WP_003644498.1\|1256564_1257443_-	elongation factor Ts	NA	NA	NA	NA
1257327:1257344	attL	NA	NA	NA	NA
WP_003640739.1\|1257545_1258349_-	30S ribosomal protein S2	NA	NA	NA	NA
WP_003640740.1\|1258573_1259296_+	HAD family hydrolase	NA	NA	NA	NA
WP_003640741.1\|1259584_1260583_-	D-2-hydroxyacid dehydrogenase	M1HKI4	Acanthocystis_turfacea_Chlorella_virus	2.3e-47	34.9
WP_003640742.1\|1260667_1260973_-	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_003644499.1\|1260956_1261715_-\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
WP_003645630.1\|1261826_1262462_+	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_003640745.1\|1262518_1262755_-	YneF family protein	NA	NA	NA	NA
WP_003644501.1\|1262852_1263092_-	DUF896 domain-containing protein	NA	NA	NA	NA
WP_003640747.1\|1263243_1263876_+	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	2.3e-16	56.2
WP_157262971.1\|1263964_1264057_-	hypothetical protein	NA	NA	NA	NA
WP_003644502.1\|1264430_1265060_+	hypothetical protein	NA	NA	NA	NA
WP_063722221.1\|1265109_1266279_-	hydroxymethylglutaryl-CoA synthase	NA	NA	NA	NA
WP_063722220.1\|1266314_1266707_-	hypothetical protein	NA	NA	NA	NA
WP_003644503.1\|1266870_1267263_+	hypothetical protein	NA	NA	NA	NA
WP_003644504.1\|1267707_1268649_+	glycosyltransferase family 2 protein	V9QJB1	Oenococcus_phage	2.4e-78	49.0
WP_024002729.1\|1269406_1269658_+	DUF4428 domain-containing protein	NA	NA	NA	NA
WP_024002728.1\|1269975_1270263_+	SHOCT domain-containing protein	NA	NA	NA	NA
WP_071665389.1\|1270407_1272273_+	DUF4428 domain-containing protein	O48432	Lactobacillus_phage	3.9e-16	26.0
WP_050495869.1\|1272289_1272892_+	DUF4428 domain-containing protein	NA	NA	NA	NA
WP_079994877.1\|1273286_1273544_-\|transposase	IS3 family transposase	A0A0C5AEA5	Paenibacillus_phage	7.6e-11	42.7
WP_015825666.1\|1273675_1274092_-\|transposase	IS3 family transposase	A0A0C5AC89	Paenibacillus_phage	9.1e-06	35.0
WP_063722215.1\|1274151_1274619_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_077726998.1\|1274866_1275256_+\|transposase	transposase	NA	NA	NA	NA
WP_024003070.1\|1275622_1276786_+\|integrase	site-specific integrase	E9LUK6	Lactobacillus_phage	1.5e-61	38.2
1283609:1283626	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1569519 : 1616670

Lactobacillus_phage(40.0%)

terminase,portal,holin,protease,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003644665.1\|1569519_1571250_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.6e-46	27.6
WP_003641420.1\|1571473_1571866_-	YxeA family protein	NA	NA	NA	NA
WP_003644667.1\|1572088_1572940_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_027821350.1\|1573378_1574521_-	ImmA/IrrE family metallo-endopeptidase	A0A0A7RTT7	Clostridium_phage	3.5e-39	28.5
WP_063722063.1\|1574528_1575200_-	hypothetical protein	NA	NA	NA	NA
WP_080469071.1\|1575309_1575609_-	LysM peptidoglycan-binding domain-containing protein	A0A0P0HRN9	Lactobacillus_phage	2.6e-10	60.4
WP_054399728.1\|1576022_1576559_-\|holin	holin	E9LUS0	Lactobacillus_phage	6.4e-36	98.8
WP_003644510.1\|1576570_1576834_-\|holin	holin	E9LUR9	Lactobacillus_phage	2.0e-38	100.0
WP_060598983.1\|1576833_1578012_-	LysM peptidoglycan-binding domain-containing protein	E9LUR8	Lactobacillus_phage	1.1e-197	88.3
WP_003642832.1\|1578139_1578574_-	hypothetical protein	NA	NA	NA	NA
WP_046811036.1\|1578576_1579026_-	DUF1617 family protein	A0A2P0ZLE0	Lactobacillus_phage	2.8e-21	40.5
WP_160257291.1\|1579047_1584351_-	hypothetical protein	Q6SE68	Lactobacillus_prophage	9.8e-145	59.6
WP_099739626.1\|1584365_1584698_-	hypothetical protein	V5UQS8	Oenococcus_phage	2.2e-42	73.4
WP_160257292.1\|1584741_1590573_-\|tail	phage tail protein	V5URV5	Oenococcus_phage	9.8e-223	40.6
WP_063722082.1\|1590588_1590852_-	hypothetical protein	V9QKH3	Oenococcus_phage	2.0e-22	64.2
WP_033608825.1\|1590959_1591358_-	hypothetical protein	V9QJA0	Oenococcus_phage	6.6e-46	74.0
WP_099447638.1\|1591457_1591841_-\|tail	phage tail protein	V5USQ9	Oenococcus_phage	1.8e-37	58.4
WP_033608826.1\|1591942_1592308_-	hypothetical protein	V5UQS4	Oenococcus_phage	1.8e-29	54.2
WP_060417584.1\|1592307_1592859_-	HK97 gp10 family phage protein	V5URV0	Oenococcus_phage	6.7e-65	62.3
WP_003642822.1\|1592860_1593208_-	hypothetical protein	V5US85	Oenococcus_phage	3.2e-36	62.3
WP_013355731.1\|1593207_1593540_-	hypothetical protein	V9QJ97	Oenococcus_phage	1.8e-12	45.3
WP_003642820.1\|1593551_1593728_-	hypothetical protein	NA	NA	NA	NA
WP_003642819.1\|1593740_1594763_-	hypothetical protein	V5US24	Oenococcus_phage	3.7e-117	62.5
WP_003642818.1\|1594782_1595133_-	hypothetical protein	V5UTH9	Oenococcus_phage	5.8e-30	62.9
WP_046947685.1\|1595147_1595825_-	DUF4355 domain-containing protein	Q6SE80	Lactobacillus_prophage	2.7e-15	32.1
WP_003642816.1\|1595997_1596204_-	hypothetical protein	NA	NA	NA	NA
WP_003642815.1\|1596255_1596534_-	hypothetical protein	NA	NA	NA	NA
WP_013355737.1\|1598340_1598598_-\|protease	ribosomal-processing cysteine protease Prp	D2J003	Enterococcus_phage	2.1e-08	39.3
WP_096587783.1\|1598566_1600075_-\|portal	phage portal protein	V5US18	Oenococcus_phage	5.8e-135	51.6
WP_033098955.1\|1600086_1601325_-\|terminase	PBSX family phage terminase large subunit	M1PG09	Streptococcus_phage	1.9e-139	61.3
WP_013355739.1\|1601314_1601842_-\|terminase	terminase small subunit	O03926	Lactobacillus_phage	4.5e-58	75.7
WP_015380624.1\|1602268_1602466_-	hypothetical protein	NA	NA	NA	NA
WP_063096770.1\|1603529_1603991_-	transcriptional regulator	D6PSV8	Lactobacillus_phage	6.3e-40	57.0
WP_071665406.1\|1604201_1604582_-	endodeoxyribonuclease	NA	NA	NA	NA
WP_057138635.1\|1604578_1605097_-	hypothetical protein	O03915	Lactobacillus_phage	2.9e-54	69.1
WP_022638119.1\|1605093_1605381_-	hypothetical protein	NA	NA	NA	NA
WP_071665407.1\|1605377_1606286_-	DnaD domain protein	NA	NA	NA	NA
WP_076633665.1\|1606364_1607225_-	hypothetical protein	A0A0P0IZH9	Lactobacillus_phage	5.0e-75	50.6
WP_021732642.1\|1607148_1608036_-	recombinase RecT	E9LUM3	Lactobacillus_phage	1.6e-60	47.0
WP_021732643.1\|1608032_1608419_-	hypothetical protein	NA	NA	NA	NA
WP_011101090.1\|1608551_1608722_-	hypothetical protein	NA	NA	NA	NA
WP_033609664.1\|1608789_1609302_-	helix-turn-helix transcriptional regulator	D6PST4	Lactobacillus_phage	8.0e-28	43.5
WP_003642793.1\|1609369_1609675_-	DUF771 domain-containing protein	NA	NA	NA	NA
WP_003642791.1\|1609881_1610178_-	hypothetical protein	NA	NA	NA	NA
WP_003642790.1\|1610177_1610384_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003642789.1\|1610525_1610756_+	helix-turn-helix transcriptional regulator	A0A0K2CNE2	Brevibacillus_phage	8.5e-06	36.8
WP_003642788.1\|1610752_1611256_+	hypothetical protein	NA	NA	NA	NA
WP_060417570.1\|1611821_1612136_+	hypothetical protein	NA	NA	NA	NA
WP_071665408.1\|1612208_1612439_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011101082.1\|1612612_1612975_+	helix-turn-helix domain-containing protein	A0A0U4KKM4	Exiguobacterium_phage	2.6e-09	32.0
WP_003644968.1\|1612986_1613400_+	ImmA/IrrE family metallo-endopeptidase	A0A0M4RD70	Bacillus_phage	3.4e-05	31.3
WP_160257293.1\|1613425_1614772_+	DUF4041 domain-containing protein	A0A1B0Y697	Lactobacillus_phage	1.5e-81	52.4
WP_063489221.1\|1614821_1615523_+	DUF3862 domain-containing protein	A0A0P0IXE0	Lactobacillus_phage	2.0e-05	80.8
WP_128531308.1\|1616334_1616670_+	hypothetical protein	A0A1B0Y4P2	Lactobacillus_phage	3.2e-25	52.2

DBSCAN-SWA_7

1824347 : 1832861

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003642593.1\|1824347_1824926_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.9e-22	35.0
WP_003642592.1\|1824918_1825944_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	8.4e-61	41.7
WP_003642591.1\|1825940_1827395_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.5e-50	34.0
WP_021356102.1\|1827379_1829599_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	3.5e-144	39.1
WP_021356103.1\|1829591_1830272_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_003642588.1\|1830271_1830526_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_021356104.1\|1830527_1831259_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4SM18	Cyanophage	2.1e-37	37.3
WP_024521791.1\|1831261_1832392_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_003642585.1\|1832375_1832861_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.3e-16	41.0

DBSCAN-SWA_8

3043758 : 3093720

Bacillus_virus(50.0%)

bacteriocin,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003643762.1\|3043758_3044322_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_011100974.1\|3044515_3045184_+	ribose 5-phosphate isomerase A	NA	NA	NA	NA
WP_003641930.1\|3045333_3046839_+	multicopper oxidase domain-containing protein	NA	NA	NA	NA
WP_003643763.1\|3047103_3047472_+	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_003641932.1\|3047584_3048094_-	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_024521227.1\|3048124_3049321_-	DUF2075 domain-containing protein	NA	NA	NA	NA
WP_003646440.1\|3049430_3049901_+	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_003641935.1\|3049919_3050375_+	hypothetical protein	NA	NA	NA	NA
WP_003641936.1\|3050478_3051051_+	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit	NA	NA	NA	NA
WP_044428959.1\|3051216_3052137_-	ribonucleoside hydrolase RihC	NA	NA	NA	NA
WP_015825107.1\|3052273_3053173_+	oxidoreductase	NA	NA	NA	NA
WP_011100979.1\|3053612_3055493_+	hypothetical protein	NA	NA	NA	NA
WP_011100980.1\|3055664_3056111_-	ribonuclease H	NA	NA	NA	NA
WP_003643770.1\|3056348_3057875_+	ABC transporter permease/substrate-binding protein	NA	NA	NA	NA
WP_003641941.1\|3057875_3058847_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.7e-23	31.7
WP_003646444.1\|3058924_3060256_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_003643773.1\|3060721_3062239_+	glycerol kinase GlpK	NA	NA	NA	NA
WP_003643774.1\|3062253_3064083_+	type 1 glycerol-3-phosphate oxidase	NA	NA	NA	NA
WP_003641945.1\|3064097_3064820_+	aquaporin family protein	M1HWZ0	Paramecium_bursaria_Chlorella_virus	3.2e-30	31.9
WP_063722046.1\|3065406_3069102_+	MucBP domain-containing protein	NA	NA	NA	NA
WP_033608293.1\|3070913_3071306_+	hypothetical protein	NA	NA	NA	NA
WP_033608294.1\|3072989_3073262_+	hypothetical protein	NA	NA	NA	NA
WP_050495849.1\|3073643_3073844_+	hypothetical protein	NA	NA	NA	NA
WP_053566430.1\|3074101_3074335_+	hypothetical protein	NA	NA	NA	NA
WP_003643792.1\|3074463_3074883_+	hypothetical protein	NA	NA	NA	NA
WP_033608295.1\|3075174_3075639_+	hypothetical protein	NA	NA	NA	NA
WP_015379760.1\|3075917_3076535_-	sugar O-acetyltransferase	NA	NA	NA	NA
WP_063722044.1\|3076538_3077693_-	MFS transporter	NA	NA	NA	NA
WP_011100993.1\|3077696_3078488_-	HAD family hydrolase	NA	NA	NA	NA
WP_003641965.1\|3078558_3079431_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_053566435.1\|3079590_3080406_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_003643798.1\|3080931_3082308_+	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_033608300.1\|3082352_3083537_+	cation:proton antiporter	NA	NA	NA	NA
WP_003643800.1\|3084197_3084341_+	hypothetical protein	NA	NA	NA	NA
WP_071665317.1\|3084810_3085017_-	hypothetical protein	NA	NA	NA	NA
WP_080029873.1\|3084986_3085316_-	hypothetical protein	NA	NA	NA	NA
WP_117288141.1\|3085422_3085626_-	hypothetical protein	NA	NA	NA	NA
WP_003643802.1\|3085781_3086297_+	Na+/H+ antiporter	NA	NA	NA	NA
WP_003641969.1\|3086501_3086705_+	hypothetical protein	NA	NA	NA	NA
WP_003643803.1\|3086939_3087092_-	hypothetical protein	NA	NA	NA	NA
WP_003643805.1\|3087116_3087785_-	hypothetical protein	NA	NA	NA	NA
WP_003641972.1\|3087781_3087955_-\|bacteriocin	two-peptide bacteriocin plantaricin JK subunit PlnK	NA	NA	NA	NA
WP_003641973.1\|3087985_3088153_-\|bacteriocin	two-peptide bacteriocin plantaricin JK subunit PlnJ	NA	NA	NA	NA
WP_003643806.1\|3089259_3090006_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_003643807.1\|3090137_3090287_+	hypothetical protein	NA	NA	NA	NA
WP_003643808.1\|3090300_3091641_+	GHKL domain-containing protein	NA	NA	NA	NA
WP_003643809.1\|3091641_3092385_+	response regulator transcription factor	NA	NA	NA	NA
WP_003643810.1\|3092689_3093463_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_003643811.1\|3093561_3093720_-\|bacteriocin	two-peptide bacteriocin plantaricin EF subunit PlnF	NA	NA	NA	NA

DBSCAN-SWA_9

3237503 : 3249638

Lactobacillus_phage(100.0%)

integrase

attL 3226539:3226553|attR 3243116:3243130

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3226539:3226553	attL	NA	NA	NA	NA
WP_160257330.1\|3237503_3238661_-\|integrase	site-specific integrase	A0A2P0ZL94	Lactobacillus_phage	1.0e-216	97.7
WP_076633252.1\|3238832_3239195_-	hypothetical protein	E9LUS2	Lactobacillus_phage	1.4e-55	88.3
WP_160257331.1\|3239388_3239949_-	hypothetical protein	A0A2P0ZL99	Lactobacillus_phage	6.8e-97	98.9
WP_160257332.1\|3240041_3240473_-	hypothetical protein	A0A2P0ZLA0	Lactobacillus_phage	4.9e-79	99.3
WP_160257333.1\|3240482_3240863_-	helix-turn-helix transcriptional regulator	A0A2P0ZLA1	Lactobacillus_phage	1.1e-55	83.1
WP_064971845.1\|3241154_3241343_+	hypothetical protein	NA	NA	NA	NA
WP_160257334.1\|3241339_3241717_-	DUF2513 domain-containing protein	NA	NA	NA	NA
WP_135517522.1\|3241781_3241988_+	XRE family transcriptional regulator	A0A2P0ZL97	Lactobacillus_phage	5.4e-28	94.1
WP_160257335.1\|3242155_3242413_-	DUF1883 domain-containing protein	NA	NA	NA	NA
WP_160257336.1\|3242485_3242686_+	hypothetical protein	A0A2P0ZLA4	Lactobacillus_phage	3.3e-30	98.5
WP_021357721.1\|3242688_3242961_+	hypothetical protein	A0A2P0ZLA9	Lactobacillus_phage	1.2e-43	100.0
WP_160257337.1\|3243098_3243380_+	hypothetical protein	NA	NA	NA	NA
3243116:3243130	attR	NA	NA	NA	NA
WP_160257338.1\|3243687_3243858_+	hypothetical protein	A0A2P0ZLA6	Lactobacillus_phage	1.3e-24	92.9
WP_160257339.1\|3243860_3244178_+	hypothetical protein	A0A2P0ZLA7	Lactobacillus_phage	2.3e-57	97.1
WP_160257340.1\|3244281_3244761_+	siphovirus Gp157 family protein	A0A2P0ZLB3	Lactobacillus_phage	4.5e-73	88.7
WP_160257341.1\|3244912_3246172_+	DEAD/DEAH box helicase	A0A2P0ZLA5	Lactobacillus_phage	1.0e-233	97.9
WP_128703125.1\|3246168_3246885_+	AAA family ATPase	A0A2P0ZLB2	Lactobacillus_phage	1.3e-113	98.6
WP_160257342.1\|3246887_3247511_+	hypothetical protein	A0A2P0ZLB9	Lactobacillus_phage	4.6e-102	97.9
WP_160257343.1\|3247581_3248376_+	DNA primase	A0A2P0ZLB0	Lactobacillus_phage	1.4e-135	91.3
WP_160257344.1\|3248372_3249638_+	helicase	A0A2P0ZLC4	Lactobacillus_phage	6.6e-225	92.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP028263

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP028261

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection