CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP046815	Vibrio cincinnatiensis strain 1398-82 chromosome 1, complete sequence	1 crisprs	DEDDh,cas6f,cas7f,cas5f,cas8f,cas3-cas2,cas1,DinG,csa3,cas3,csx1	0	7	3	0
NZ_CP046816	Vibrio cincinnatiensis strain 1398-82 chromosome 2, complete sequence	4 crisprs	DEDDh,RT	0	14	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046815_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046815_1

374560-375787

TypeI-F

I-F

Consensus_repeat	Method
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CRISPRCasFinder
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CRT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	PILER-CR

20 spacers

cas6f,cas7f,cas5f,cas8f,cas3-cas2,cas1

The CRISPR arrays of NZ_CP046815_1

>merge|NZ_CP046815|1|374560-375787|CRISPRCasFinder,CRT,PILER-CR
TTTAGGTGCACAATATACGGCAGTGAACGATATCGTCCACGCCATCAACGTGCTGGCGATTTTCTAAGCTGCCTATGCGGCAGTGAACCTGTCATTCATCAAGGGGCGCGTGGGCCGCAATTTCTAAGCTGCCTATGCGGCAGTGAACCGATACTCACACTGTTTCGAATACCCCTTTAATTTCTAAGCTGCCTATGCGGCAGTGAACACTTAGTTAAGGAGGCCGCCCCAGTGCTTATCTTTCTAAGCTGCCTATGCGGCAGTGAACCTGTCCAAGGAAATGGCAATTTGTACTCAGTATTTCTAAGCTGCCTATGCGGCAGTGAACCCCGATGTATTGTTATTCGTAGTGTTGCTTGATTTCTAAGCTGCCTATGCGGCAGTGAACGTAATATGTGCTGCGTGCAGCCTGTTCTACAGTTTCTAAGCTGCCTATGCGGCAGTGAACATTGTTCCAGGGGTAAAGCGCCCTCGCGCATATTTCTAAGCTGCCTATGCGGCAGTGAACGACTCAATCGGACGCCCCCAAACATCTACAATTTTCTAAGCTGCCTATGCGGCAGTGAACAGGGACGAAATCGGTGATCAGCACCTCTTCATTTTCTAAGCTGCCTATGCGGCAGTGAACCGTAGCTTTTTCGCGGTTGGTGGCTCCTTCGGTTTCTAAGCTGCCTATGCGGCAGTGAACAAAATTCTTCTATTTTACTCAAGGCGCTTACTTTTCTAAGCTGCCTATGCGGCAGTGAACCTCAACTCAGACCAAGCCTACTACGTGTTAGATTTCTAAGCTGCCTATGCGGCAGTGAACCAAACCAGACAATAACCCCTCAGTGGCGAGTTTTTCTAAGCTGCCTATGCGGCAGTGAACGGGGGATGCTGCTCTACATCTTTATCTTCGAATTTCTAAGCTGCCTATGCGGCAGTGAACGGAAATACGTTGACCACCGAAAGAGCGTGAGCTTTCTAAGCTGCCTATGCGGCAGTGAACTTTCATATAACCCCCGATGGTTACTTAGTTAATTTCTAAGCTGCCTATGCGGCAGTGAACGCCGATTTTAAATAGATATATTGACCGTCTAATTTCTAAGCTGCCTATGCGGCAGTGAACCTGGTGATTTGCCTGTTCTTAAATTTTCACTATTTCTAAGCTGCCTATGCGGCAGTGAACCTCTACGTGACTACTTTGCAAACAATGATTATTTTCTAAGCTGCCTATGCGGCAGTGAAC

>NZ_CP046815|1|1|374560-375787|CRISPRCasFinder
TTTAGGTGCACAATATACGGCAGTGAAC	GATATCGTCCACGCCATCAACGTGCTGGCGAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CTGTCATTCATCAAGGGGCGCGTGGGCCGCAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CGATACTCACACTGTTTCGAATACCCCTTTAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ACTTAGTTAAGGAGGCCGCCCCAGTGCTTATC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CTGTCCAAGGAAATGGCAATTTGTACTCAGTA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CCCGATGTATTGTTATTCGTAGTGTTGCTTGA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GTAATATGTGCTGCGTGCAGCCTGTTCTACAG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ATTGTTCCAGGGGTAAAGCGCCCTCGCGCATA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GACTCAATCGGACGCCCCCAAACATCTACAAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AGGGACGAAATCGGTGATCAGCACCTCTTCAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CGTAGCTTTTTCGCGGTTGGTGGCTCCTTCGG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AAAATTCTTCTATTTTACTCAAGGCGCTTACT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CTCAACTCAGACCAAGCCTACTACGTGTTAGA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CAAACCAGACAATAACCCCTCAGTGGCGAGTT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GGGGGATGCTGCTCTACATCTTTATCTTCGAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GGAAATACGTTGACCACCGAAAGAGCGTGAGC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TTTCATATAACCCCCGATGGTTACTTAGTTAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GCCGATTTTAAATAGATATATTGACCGTCTAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CTGGTGATTTGCCTGTTCTTAAATTTTCACTA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CTCTACGTGACTACTTTGCAAACAATGATTAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC

>NZ_CP046815|1|1|374560-375787|CRT
TTTAGGTGCACAATATACGGCAGTGAAC	GATATCGTCCACGCCATCAACGTGCTGGCGAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CTGTCATTCATCAAGGGGCGCGTGGGCCGCAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CGATACTCACACTGTTTCGAATACCCCTTTAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ACTTAGTTAAGGAGGCCGCCCCAGTGCTTATC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CTGTCCAAGGAAATGGCAATTTGTACTCAGTA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CCCGATGTATTGTTATTCGTAGTGTTGCTTGA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GTAATATGTGCTGCGTGCAGCCTGTTCTACAG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ATTGTTCCAGGGGTAAAGCGCCCTCGCGCATA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GACTCAATCGGACGCCCCCAAACATCTACAAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AGGGACGAAATCGGTGATCAGCACCTCTTCAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CGTAGCTTTTTCGCGGTTGGTGGCTCCTTCGG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AAAATTCTTCTATTTTACTCAAGGCGCTTACT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CTCAACTCAGACCAAGCCTACTACGTGTTAGA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CAAACCAGACAATAACCCCTCAGTGGCGAGTT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GGGGGATGCTGCTCTACATCTTTATCTTCGAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GGAAATACGTTGACCACCGAAAGAGCGTGAGC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TTTCATATAACCCCCGATGGTTACTTAGTTAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GCCGATTTTAAATAGATATATTGACCGTCTAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CTGGTGATTTGCCTGTTCTTAAATTTTCACTA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CTCTACGTGACTACTTTGCAAACAATGATTAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC

>NZ_CP046815|1|1|374620-375787|PILER-CR
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CTGTCATTCATCAAGGGGCGCGTGGGCCGCAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CGATACTCACACTGTTTCGAATACCCCTTTAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ACTTAGTTAAGGAGGCCGCCCCAGTGCTTATC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CTGTCCAAGGAAATGGCAATTTGTACTCAGTA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CCCGATGTATTGTTATTCGTAGTGTTGCTTGA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GTAATATGTGCTGCGTGCAGCCTGTTCTACAG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ATTGTTCCAGGGGTAAAGCGCCCTCGCGCATA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GACTCAATCGGACGCCCCCAAACATCTACAAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AGGGACGAAATCGGTGATCAGCACCTCTTCAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CGTAGCTTTTTCGCGGTTGGTGGCTCCTTCGG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AAAATTCTTCTATTTTACTCAAGGCGCTTACT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CTCAACTCAGACCAAGCCTACTACGTGTTAGA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CAAACCAGACAATAACCCCTCAGTGGCGAGTT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GGGGGATGCTGCTCTACATCTTTATCTTCGAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GGAAATACGTTGACCACCGAAAGAGCGTGAGC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TTTCATATAACCCCCGATGGTTACTTAGTTAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GCCGATTTTAAATAGATATATTGACCGTCTAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CTGGTGATTTGCCTGTTCTTAAATTTTCACTA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CTCTACGTGACTACTTTGCAAACAATGATTAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046815.1\|WP_078924976.1\|377572_378748_-\|type-I-F-CRISPR-associated-protein-Csy2	cas5f	cd09736_cas5f_CAS-I-F	gnl\|CDD\|378221
NZ_CP046815.1\|WP_078924975.1\|376591_377554_-\|type-I-F-CRISPR-associated-protein-Csy3	cas7f	pfam09615_cas7f_CAS-I-F	gnl\|CDD\|378222
NZ_CP046815.1\|WP_158117196.1\|367469_368474_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|234672
NZ_CP046815.1\|WP_078924977.1\|378744_380229_-\|type-I-F-CRISPR-associated-protein-Csy1	cas8f	pfam09611_cas8f_CAS-I-F	gnl\|CDD\|187866
NZ_CP046815.1\|WP_078924968.1\|366172_366418_-\|molybdopterin-synthase-sulfur-carrier-subunit	unknown	unknown	gnl\|CDD\|182985
NZ_CP046815.1\|WP_078924974.1\|375942_376581_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	cas6f	pfam09618_cas6f_CAS-I-F	gnl\|CDD\|187870
NZ_CP046815.1\|WP_078924979.1\|383604_384594_-\|type-I-F-CRISPR-associated-endonuclease-Cas1	cas1	cd09718_cas1_CAS-I-F	gnl\|CDD\|132676
NZ_CP046815.1\|WP_078924966.1\|365147_365564_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341392
NZ_CP046815.1\|WP_078925225.1\|389688_390894_-\|NupC/NupG-family-nucleoside-CNT-transporter	unknown	unknown	gnl\|CDD\|224883
NZ_CP046815.1\|WP_078924973.1\|371685_373716_-\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
NZ_CP046815.1\|WP_078927663.1\|387077_388112_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|226077
NZ_CP046815.1\|WP_078924978.1\|380218_383608_-\|type-I-F-CRISPR-associated-helicase-Cas3	cas3-cas2	cas3-cas2-CAS-I-F	gnl\|CDD\|274201
NZ_CP046815.1\|WP_078924971.1\|368762_369653_+\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NZ_CP046815.1\|WP_078924970.1\|366904_367417_-\|molybdenum-cofactor-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|131715
NZ_CP046815.1\|WP_078927663.1\|384981_386016_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|226077
NZ_CP046815.1\|WP_078924969.1\|366414_366894_-\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NZ_CP046815.1\|WP_078924967.1\|365717_366167_-\|molybdopterin-synthase-catalytic-subunit-MoaE	unknown	unknown	gnl\|CDD\|182642
NZ_CP046815.1\|WP_115174053.1\|369990_371355_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NZ_CP046815.1\|WP_078925224.1\|388743_389613_+\|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD	unknown	unknown	gnl\|CDD\|236760
NZ_CP046815.1\|WP_078924991.1\|369645_369984_-\|Hpt-domain-containing-protein	unknown	unknown	gnl\|CDD\|366732

Protein	Function_ID	Function_description	E-value
NZ_CP046815.1\|WP_078924976.1\|377572_378748_-\|type-I-F-CRISPR-associated-protein-Csy2	gnl\|CDD\|378221	pfam09614, Cas_Csy2, CRISPR-associated protein (Cas_Csy2). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2464 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy2, for CRISPR/Cas Subtype Ypest protein 2.	7.9907e-91
NZ_CP046815.1\|WP_078924975.1\|376591_377554_-\|type-I-F-CRISPR-associated-protein-Csy3	gnl\|CDD\|378222	pfam09615, Cas_Csy3, CRISPR-associated protein (Cas_Csy3). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2463 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy3, for CRISPR/Cas Subtype Ypest protein 3.	6.48838e-130
NZ_CP046815.1\|WP_158117196.1\|367469_368474_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|234672	PRK00164, moaA, GTP 3',8-cyclase MoaA.	0
NZ_CP046815.1\|WP_078924977.1\|378744_380229_-\|type-I-F-CRISPR-associated-protein-Csy1	gnl\|CDD\|187866	cd09735, Csy1_I-F, CRISPR/Cas system-associated protein Csy1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins; Predicted subunit of the Cascade complex; signature gene for I-F subtype; also known as Csy1 family.	8.09707e-53
NZ_CP046815.1\|WP_078924968.1\|366172_366418_-\|molybdopterin-synthase-sulfur-carrier-subunit	gnl\|CDD\|182985	PRK11130, moaD, molybdopterin synthase small subunit; Provisional.	4.94061e-49
NZ_CP046815.1\|WP_078924974.1\|375942_376581_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	gnl\|CDD\|187870	cd09739, Cas6_I-F, CRISPR/Cas system-associated RAMP superfamily protein Cas6f. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6f is an endoribonuclease that generates crRNA; This family is specific for CRISPR/Cas system I-F subtype; Possesses RRM fold; also known as Csy4 family.	2.80004e-57
NZ_CP046815.1\|WP_078924979.1\|383604_384594_-\|type-I-F-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|132676	TIGR03637, cas1_YPEST, CRISPR-associated endonuclease Cas1, subtype I-F/YPEST. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the YPEST subtype of CRISPR/Cas system.	6.66989e-170
NZ_CP046815.1\|WP_078924966.1\|365147_365564_-\|CBS-domain-containing-protein	gnl\|CDD\|341392	cd04629, CBS_pair_bac, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains present in bacteria. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	9.55027e-54
NZ_CP046815.1\|WP_078925225.1\|389688_390894_-\|NupC/NupG-family-nucleoside-CNT-transporter	gnl\|CDD\|224883	COG1972, NupC, Nucleoside permease [Nucleotide transport and metabolism].	3.11634e-170
NZ_CP046815.1\|WP_078924973.1\|371685_373716_-\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP046815.1\|WP_078927663.1\|387077_388112_-\|IS110-family-transposase	gnl\|CDD\|226077	COG3547, COG3547, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.0419e-36
NZ_CP046815.1\|WP_078924978.1\|380218_383608_-\|type-I-F-CRISPR-associated-helicase-Cas3	gnl\|CDD\|274201	TIGR02562, conserved_hypothetical_protein, CRISPR-associated helicase Cas3, subtype I-F/YPEST. The helicase in many CRISPR-associated (cas) gene clusters is designated Cas3, and most Cas3 proteins are described by model TIGR01587. Members of this family are considerably larger, show a number of motifs in common with TIGR01587 sequences, and replace Cas3 in some CRISPR/cas loci in a number of Proteobacteria, including Yersinia pestis, Chromobacterium violaceum, Erwinia carotovora subsp. atroseptica SCRI1043, Photorhabdus luminescens subsp. laumondii TTO1, Legionella pneumophila, etc.	0
NZ_CP046815.1\|WP_078924971.1\|368762_369653_+\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	3.63252e-134
NZ_CP046815.1\|WP_078924970.1\|366904_367417_-\|molybdenum-cofactor-biosynthesis-protein-B	gnl\|CDD\|131715	TIGR02667, Molybdenum_cofactor_biosynthesis_protein_B., molybdenum cofactor biosynthesis protein B, proteobacterial. This model represents the MoaB protein molybdopterin biosynthesis regions in Proteobacteria. This crystallized but incompletely characterized protein is thought to be involved in, though not required for, early steps in molybdopterin biosynthesis. It may bind a molybdopterin precursor. A distinctive conserved motif PCN near the C-terminus helps distinguish this clade from other homologs, including sets of proteins designated MogA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.35313e-105
NZ_CP046815.1\|WP_078927663.1\|384981_386016_+\|IS110-family-transposase	gnl\|CDD\|226077	COG3547, COG3547, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.0419e-36
NZ_CP046815.1\|WP_078924969.1\|366414_366894_-\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	1.86762e-102
NZ_CP046815.1\|WP_078924967.1\|365717_366167_-\|molybdopterin-synthase-catalytic-subunit-MoaE	gnl\|CDD\|182642	PRK10678, moaE, molybdopterin synthase catalytic subunit MoaE.	1.47833e-81
NZ_CP046815.1\|WP_115174053.1\|369990_371355_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	0
NZ_CP046815.1\|WP_078925224.1\|388743_389613_+\|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD	gnl\|CDD\|236760	PRK10792, PRK10792, bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD.	0
NZ_CP046815.1\|WP_078924991.1\|369645_369984_-\|Hpt-domain-containing-protein	gnl\|CDD\|366732	pfam01627, Hpt, Hpt domain. The histidine-containing phosphotransfer (HPt) domain is a novel protein module with an active histidine residue that mediates phosphotransfer reactions in the two-component signaling systems. A multistep phosphorelay involving the HPt domain has been suggested for these signaling pathways. The crystal structure of the HPt domain of the anaerobic sensor kinase ArcB has been determined. The domain consists of six alpha helices containing a four-helix bundle-folding. The pattern of sequence similarity of the HPt domains of ArcB and components in other signaling systems can be interpreted in light of the three-dimensional structure and supports the conclusion that the HPt domains have a common structural motif both in prokaryotes and eukaryotes. In S. cerevisiae ypd1p this domain has been shown to contain a binding surface for Ssk1p (response regulator receiver domain containing protein pfam00072).	2.16965e-07

>NZ_CP046815.1|WP_078924973.1|371685_373716_-|excinuclease-ABC-subunit-UvrB
MNKAFELVSHYQPSGDQPDAIQRLLDGIDAGLAHQTLLGVTGSGKTFTLANVIAKAQRPTILLAPNKTLAAQLYGEMKSFFPHNAVEYFVSYYDYYQPEAYVPTTDTFIEKDASVNAHIEQMRLSATKALLERKDAIIVASVSAIYGLGDPDSYLKMMLHLRRGDVLNQRDMLRRLAELQYTRNEMAFERGQFRVRGEVIDIFPAESEQEAVRVEMFDDEVECISLFDPLTGAVKQRDLARYTIYPKTHYVTPRERILEAIELIKQELQLRRQYLLENNKLLEEQRISQRTQFDIEMMNELGFCSGIENYSRYLSGRSEGEPPPTLFDYLPHDGLLVIDESHVTVPQIGAMYKGDRSRKETLVEFGFRLPSALDNRPLKFDEFEALAPQTIFVSATPSHYELEKSAGEVVEQVVRPTGLLDPELEVRPVATQVDDLLSEIRLRSVKDERVLVTTLTKRMAEDLTEYLHEHGVKVRYLHSDIDTVERVEIIRDLRLGVFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARHLEGKAILYADTVTKSMQKAMDETERRREKQHAYNEKMGIQPQALKRNINDIMELGDATKARKQKASRIVPLSKVAEEGAGYANLTPQQLEKEILKLETQMYKHAQELEFEQAAAKRDQIETLRQQFIVNS
>NZ_CP046815.1|WP_115174053.1|369990_371355_-|sigma-54-dependent-Fis-family-transcriptional-regulator
MVEDTASVAALYRSYLTPLEIDITIVGTGRAAIESLNRRKPDLILLDLRLPDMTGMDVLHAVKERSADVPIIFMTAHGSIDTAVEAMRYGAQDFLIKPCEADRLRVTVNNAIRKASKLKNNPSHSTNSNYQGFIGSSQTMQAVYRTIDSAASSKASIFITGESGTGKEVCAEAIHAASKRGEKPFIAINCAAIPKDLIESELFGHVKGAFTGAAVDRQGAAELADGGTLFLDELCEMDLDLQTKLLRFIQTGTFQKVGSSKMHSVDVRFVCATNRDPWKEVQAGRFREDLYYRLYVIPLHLPPLRERGEDVIEIAYSLLGHMSKEEGKEFVRLSPEVIERFKHYEWPGNVRQLQNVLRNVVVLNNGQEITLPMLPPPLNLPRIQERSVAPQPVDTGLSVHDIFPLWMTEKQAIEKAIEACDGNIPRAASYLDVSPSTIYRKLQAWNEKEQEKEQ
>NZ_CP046815.1|WP_078924991.1|369645_369984_-|Hpt-domain-containing-protein
MEWMNQYKIDHLSQEIGAENIPMLIEIFLGELEAYQKNLTSESVDSHLDYLAEISHALKSSAASFGADRLYAKAQMLDSLFKQGEAMDEATEVASMIDELNHTAKHYYRLIN
>NZ_CP046815.1|WP_078924971.1|368762_369653_+|YvcK-family-protein
MSLYEHKKVVAIGGGHGLGRMLAALKVFGANATGIVTTTDNGGSTGRIRHCQGGIAWGDTRNCINQLITEPSISSMMFEYRFKGAGELNGHNLGNLMLTALDHLSVRPLDAINLIRNMLKVDVNIVPMSEHPSDLTALSTGGKWVTGETNVDEMKQDLLRLDLDPEVPATREGVHAIDQADAIILGPGSFLTSVMPPLLLPEVGQAIANNVRAKLIFVENLSPEYGPAGRMSLEQKLEWCERACQARQIDVIIGAEPHPDLADKWNCVTRDLASPNRDWRHDRVKLRQAIEEQLIN
>NZ_CP046815.1|WP_158117196.1|367469_368474_-|GTP-3',8-cyclase-MoaA
MERCSVAQQFEDRFQRKFYYLRLSITDVCNFKCTYCLPEGYQPAGKKNSSFLTLSEIQRIVRAFAHCGTSKVRITGGEPSLRKDFTEIIHTVANEKGIEKIATTTNGYRMAKDVGQWKQAGLTHINVSVDSLDPRMFQQITGENRFYQVMQGIDRAFEVGFEQVKVNVVLMKDLNAQALPQFLAWIQHRPIQLRFIELMQTGEMDSLFTQHHVSGIALRNQLMADGWVLKARAHNDGPAQVYVHADYQGEIGLIMPYEKNFCHSCNRLRISALGKLHLCLFGEQGIQLRDLLQEDEQQAALIERIQTQLQNKSESHFLHDGNTGMTPHLASIGG
>NZ_CP046815.1|WP_078924970.1|366904_367417_-|molybdenum-cofactor-biosynthesis-protein-B
MGHAESKFQPANIAVLTVSDTRTEDNDTSGRYLADQLIEAGHTLADKQIVIDDRYKIRAIVSQWIADEQVQVVLITGGTGFTSRDSTPEALKPLFDKEVEGFGELFRMVSYEEIGTSTIQSRAVAGFANHTVVFAMPGSTGACRTGWTKIIKQQLDASHRPCNFMPHLSV
>NZ_CP046815.1|WP_078924969.1|366414_366894_-|cyclic-pyranopterin-monophosphate-synthase-MoaC
MNQFSHINASGEANMVDVSAKLDTVREARAEAYVRMTPETLKLIVSGQHHKGDVFATARIAGIQAAKKTWDLIPLCHPLLLSKVEVNLEALEHESRVRIESVCKLAGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIEQVRLLEKVGGKSGHFKAEQ
>NZ_CP046815.1|WP_078924968.1|366172_366418_-|molybdopterin-synthase-sulfur-carrier-subunit
MIKVLFFAQTRELLGCDHIELEACFETVEMLRQHLSQQEGKWSLALQADKLLAAVNQSIVSMAHPLQAGDEVAFFPPVTGG
>NZ_CP046815.1|WP_078924967.1|365717_366167_-|molybdopterin-synthase-catalytic-subunit-MoaE
MDSRVSVQHHDFSVADEYTALAQGSGAGAIVTFVGKVRDMNLGDDVVGLHLEHYPGMTEKALLTICDEAQSRWPLQKVRVIHRIGDMDAGEQIVFVGVTSAHRNASFEACEFIMDTLKTRAPFWKKERTTESTRWVESRDSDHQAAQRW
>NZ_CP046815.1|WP_078924966.1|365147_365564_-|CBS-domain-containing-protein
MDSLKVRDYMTVQAVTFTPEMPLSAALDRVMHSHHLGGPVIDEHKRVIGFLSEQDLLDKLVKVSYFCQDSHIVSDCMHKEVLFVSPDMSIIELADMMKVGKPKVYPVVEQGRLVGIITRRDVLLAIAKNLTACFKHPV
>NZ_CP046815.1|WP_078924974.1|375942_376581_-|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4
MNYYQEITLLPEAEIPLAFLWQNVFQQVHIALVEHKVGSNQSLVAVGFPDYRQAKFPLGSKLRLFAKDQATLENLDIHHWLTRLEDYVHIKGIKPVPNDVNYVSFVRKQVKSPERIERDMQQKAALWAAKSGKPLVECLADLQQSKPTALCSLPFIYLHSQQTKQRSPEKSSKFPLFIQMQQQSTSQDGSFDCYGLSSKASGQSALATVPHF
>NZ_CP046815.1|WP_078924975.1|376591_377554_-|type-I-F-CRISPR-associated-protein-Csy3
MTKKITLPSMLAFERKLEPSDALMTAGDWNNKDKAWDGIKISVLPRTLRGTKSQFNLDKGGREDNNISEGDDAYLPNDLDTLKVSFSLRVIGDLGAPFGCNDPDFSRSIKERVLAYKPEGLKELAYRYAHNIAAGRFLWRNRVAAEQLYIQITVNDQDAIVFNGYDFSLKTFEKQRDNADLMKVANAIFEGLNSDEQFICLTVDAFVKLGKGQHVFPSQEMNMGEKKKVLFKLDNCAAMHSVKIGNAIRTIDDWYDNAELPIAIEPFGAVTQQGHAYRKTKTDLYTLMMKWVNDEEVSENDKNFVLANLIRGGVFGGKAE
>NZ_CP046815.1|WP_078924976.1|377572_378748_-|type-I-F-CRISPR-associated-protein-Csy2
MTQYLLLNRIKVQNANAVAGFTWGFPAITHFLGFTHNLSRKLARSKYQGVSLKGCAVVAHEHHVHTFGKYNDRFLQSKTPAYLLGDVNKVVQGGAPSIVEEGKMNMTVSLVIEFDGFIGREVGELLSWVKRQCLMQRLAGGSILTIGDVKLLDGNNQQDIFKLKRVLLPGFVLMDRSNYLAEHYQNCLSKNSEAEQLDAWLDFIVLKQQARPISTLISKHLQGMDDSTLYDIWLEHLEQPYSNNIPQELSEYFSKLEESKKTKLLLKQWEEYMNPTGKTDADWQYLSKPKVGYLVPIMTGYKAISSVYDNCDIANTRDSETPVCFVEAVHSVGEWLGVNRLKNGEDIASCLWTYQYDDGWYLCQQIIQKEIEESDIEQQVLALFDPIDDLV
>NZ_CP046815.1|WP_078924977.1|378744_380229_-|type-I-F-CRISPR-associated-protein-Csy1
MVNEIKQSSWKNVIESYIKSLEEYSKQSDYRNELLAIFVSKKLLSLVSGEDEAEIKKFLIYIRKIPVTAKNKDKLIAAYQTAIDKGWIKSISDEIEKISRKSNFINIWIARSVEISEGVLPATHCAKLTHSSSSGSSILDASSNSRSEYVSTSSMQERTIDGTYLNAVFSKQVKFLMLKFNDSYLFEEIQKGNGSALVDFAEDDEELNYWIKSYQAILNEKPKADILLKQLYFPVDKNYHLLVMLQSSSLAQNLYERCFDKEARKKQGQYTKARNSSKFTPDMQQNFVGVSKLLITQSQHQNATVFNGKRGGIQRLFNTQPPTWVVQTKPPINQKSWFYNGIPNSAIKTDIDYLRDFLLRNEQLSLSTRNPQKRKWLIKWGQSLTDTVLFHAQQIRLLPAGWSGLESIKLKLSQQYFLDPYRDDETFQAARKTIDWQSEVSKDFAKWVNGKLIGKDKRFTPQAEHTKLWALLMSNALREITIVPERVKNMGETV
>NZ_CP046815.1|WP_078924978.1|380218_383608_-|type-I-F-CRISPR-associated-helicase-Cas3
MMVTFVSQCEKNALKKTRRVLDAFANRIGDNTWQTLITEEGLVTVKKMLRQTASRSTAVSCHWIRSRSRSQFLWVVGNKKKFNSEGYVPVNYTEKEMTGFYDSASWKTLDAIASAAAIAGLFHDFGKANVLFQKKLDPNVKTENSEPYRHEWISLRLFQAFVGSHDDVKWLEKLAEQQFENIPDCFKDGVEHGFGAHPILSLPPFAQLVAWIIVSHHKLPLCPAWQDSINAPALKDIDKWLINSFDANWNSYQCNAVEQKHRVQENWSFSEGALPYHSKKWCSHASNVASIALANLLSREYFEQDYINDHVFTSHLARLAMMLADRYYSSQLEVTPEWRSSKYYTHANTYDKSAGKTGLKQQLDEHLIGVAIHSKDIVRALPKLKFSLPKLEDATSLSELIRNSDKEFEKYGWQNSAQKLASKLGRESTNNGFFAINMASTGKGKTITNAKIMYAIGEQTGNKRFSVALGLRTLTLQTGREFKDSIGLNDEQLAIAVGGSAVKQLFENEQNKENGTNERSCGSESAEENLNEEIYTHYDGNTVHSLSQWTAHDKNIDKLLSAPVLVCTIDHLISATEGTKGGRQTAAMLRLLSSDLVLDEPDDFGLSDLPALCRLVHWAGMLGSRVLLSTATMPPALAFALFESYRTGWQQYAKANLTDWSGNICCAWFDENTVSDAEKSQIADLTSFKSEHGKFVNKRLSFLHSEQSKAKRIGKIVEIERSDGDSPLQAIARTIYNQFSQLHRKHHTSQNGKTVSIGLVRMANINPLVNVAQNLIAFDAPVIEQNNDCCIHFCIYHSRYPLAVRSEIENKLDTALKRKHANKIFDSSHPVGRVIKNFPQKHHIFVVLASPVAEVGRDHDYDWAIVEPSSMRSIIQLAGRVLRHRDKSIIEPNIVLLNQNYKALNGREICFARPGFEMKSSTESLLLDKTLNLKGLLRKDTYEIINAIPRITLPDKEQYLPNKDGFYIDLNGLEHKALAWQLFSGDRNAKVWWNAEKQQMPYWCAEVQRQQQFRKSHQDEAYYLMFDGEFGKPYWCWLNENVHPVKFGEVTEIGITTVPRVPLGENSYFWLDQSVESVYQALANDLNMDICEIGKRFGELRITEFDNSSNREYCYHNNFGLYQEVDNGE
>NZ_CP046815.1|WP_078924979.1|383604_384594_-|type-I-F-CRISPR-associated-endonuclease-Cas1
MDDLSPSDLKVILHSKRANMYYLEYCRVMQKDGRVLYLTEADKENLYFNIPIANTTVLMLGNGTSITQAAMRMLSQAGVLVGFCGGGGTPLHMACEVEWFTPQSEYRPTEYLQGWLSFWFDDQKRLAAAKQFQNARIDYLQRVWRSDRELTLEKFNVQDEVIQQSLATFHQRTDAASKQSDLLLTEAQLTKALYKYAANNTGKDGFTRQHQPDKKSTDKANDFLNHGNYLAYGLAASCLWVLGIPHGFAVMHGKTRRGALVFDVADLIKDAIVLPWAFVYAKENATEQEFRQQILQSFIEHKALDFMFDTVKQVALQGKGEEESEAREL
>NZ_CP046815.1|WP_078927663.1|384981_386016_+|IS110-family-transposase
MSIKVVGIDIAKNLFQVCVLGTNGQILSNRKVKRDKLLDTVRQLPEQTALAMESCATSHHWGRIFQELGYTVALIPAQHVKPFVGRQKNDANDARAICEAYSRPNLHFVPVKSVEQQDLKAIRSVRKRLVENRTALANQIRGLAAEYGVVFPLSIKALRSHLPLALEDAENALSPVMRNLLQTLYCDFVSLSEEIDEMTQSVTILSQQNPKYEAIRNIPGFGPILTAALISEVGVGNQFQNGRQFSAWCGLVPKQNSTGGKSSLGSLSKNGNRELRALLIHGARAVLRCGANKTDAMGAWLRGLIARRGKAKAIVALANKLGRVAWHILAKNSEYDINQAFKPV
>NZ_CP046815.1|WP_078927663.1|387077_388112_-|IS110-family-transposase
MSIKVVGIDIAKNLFQVCVLGTNGQILSNRKVKRDKLLDTVRQLPEQTALAMESCATSHHWGRIFQELGYTVALIPAQHVKPFVGRQKNDANDARAICEAYSRPNLHFVPVKSVEQQDLKAIRSVRKRLVENRTALANQIRGLAAEYGVVFPLSIKALRSHLPLALEDAENALSPVMRNLLQTLYCDFVSLSEEIDEMTQSVTILSQQNPKYEAIRNIPGFGPILTAALISEVGVGNQFQNGRQFSAWCGLVPKQNSTGGKSSLGSLSKNGNRELRALLIHGARAVLRCGANKTDAMGAWLRGLIARRGKAKAIVALANKLGRVAWHILAKNSEYDINQAFKPV
>NZ_CP046815.1|WP_078925224.1|388743_389613_+|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD
MTAQNIDGKLISQTVRSEVAARVKARIDAGRRAPGLAVVLVGEDPASQVYVGSKRRACEEVGFVSQSYDLPANTSEAELLALIDNLNADTSIDGILVQLPLPAGIDTTQVLERILPDKDVDGFHPYNVGRLAQRIPTLRSCTPKGIITLLERYNIPLRGKHAVIVGASNIVGRPMTLELLLAGCTTTTCHRFTKDLEQHVRQADVLVVAVGKPHFIPGAWVKEGAVVIDVGINRLDTGKLVGDVDYEVASTRASFITPVPGGVGPMTVASLIENTLMACEQFHTLDRHQ
>NZ_CP046815.1|WP_078925225.1|389688_390894_-|NupC/NupG-family-nucleoside-CNT-transporter
MSSLLGVAAILCIAWLLSTNRKNIQLKTVIPAFLLQVGFALLVLYVPMGKEVLNKVTGAVSHLIDYGQEGISFIFGGLASSNIGFVFAINVLGIIIFFSALISGLYHLGIMPKVINIIGGGIQKCLGTGRAESLSATANIFVGMIEAPLVVKPYLKHMSDSQFFAVMTCGLASVAGGTLVGYASLGVNLNYLIAAAFMSAPAGLLMAKMLVPETEPHTLQQADDEVDIPKATNVVEAVADGAMSGLRIAAAVGATLLAFVSVIALLNGLLGWAGSVVGIELSFELILGYLFAPIAWLLGIPWNEAITAGALIGNKIIVNEFVAFIQLMNVQSQLSEHSQAIVTFALCGFANISTMAVLIGGLGSLVPERRSFISQYGFRAISAGVLANLMSAALAGVILSL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP046815_1	1.2\|374648\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	374648-374679	32	NC_010113	Vibrio sp. 0908 plasmid p0908, complete sequence	79202-79233	0	1.0
NZ_CP046815_1	1.2\|374648\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	374648-374679	32	NZ_CP046830	Vibrio parahaemolyticus strain 2012AW-0224 plasmid unnamed1, complete sequence	26681-26712	0	1.0
NZ_CP046815_1	1.1\|374588\|32\|NZ_CP046815\|CRISPRCasFinder,CRT	374588-374619	32	MH338234	Mycobacterium phage Crucio, complete genome	5846-5877	6	0.812
NZ_CP046815_1	1.1\|374588\|32\|NZ_CP046815\|CRISPRCasFinder,CRT	374588-374619	32	MH697591	Mycobacterium phage QueenBeesly, complete genome	5846-5877	6	0.812
NZ_CP046815_1	1.1\|374588\|32\|NZ_CP046815\|CRISPRCasFinder,CRT	374588-374619	32	MT498060	Mycobacterium Phage FiringLine, complete genome	5846-5877	6	0.812
NZ_CP046815_1	1.1\|374588\|32\|NZ_CP046815\|CRISPRCasFinder,CRT	374588-374619	32	KM463009	Mycobacterium phage Power, complete genome	5846-5877	6	0.812
NZ_CP046815_1	1.1\|374588\|32\|NZ_CP046815\|CRISPRCasFinder,CRT	374588-374619	32	MT498066	Mycobacterium phage Georgie2, complete genome	5847-5878	6	0.812
NZ_CP046815_1	1.1\|374588\|32\|NZ_CP046815\|CRISPRCasFinder,CRT	374588-374619	32	MN234203	Mycobacterium phage SemperFi, complete genome	6274-6305	6	0.812
NZ_CP046815_1	1.1\|374588\|32\|NZ_CP046815\|CRISPRCasFinder,CRT	374588-374619	32	MF919531	Mycobacterium phage SnapTap, complete genome	5846-5877	6	0.812
NZ_CP046815_1	1.1\|374588\|32\|NZ_CP046815\|CRISPRCasFinder,CRT	374588-374619	32	NC_029043	Mycobacterium phage SweetiePie, complete genome	5846-5877	6	0.812
NZ_CP046815_1	1.1\|374588\|32\|NZ_CP046815\|CRISPRCasFinder,CRT	374588-374619	32	NZ_HG938356	Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence	986087-986118	7	0.781
NZ_CP046815_1	1.1\|374588\|32\|NZ_CP046815\|CRISPRCasFinder,CRT	374588-374619	32	NZ_CP031193	Humibacter sp. BT305 plasmid unnamed1	94005-94036	8	0.75
NZ_CP046815_1	1.11\|375188\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	375188-375219	32	KP010268	Enterobacteria phage SfMu, complete genome	15693-15724	8	0.75
NZ_CP046815_1	1.1\|374588\|32\|NZ_CP046815\|CRISPRCasFinder,CRT	374588-374619	32	NZ_CP050096	Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b3, complete sequence	103342-103373	9	0.719
NZ_CP046815_1	1.1\|374588\|32\|NZ_CP046815\|CRISPRCasFinder,CRT	374588-374619	32	NZ_CP033227	Sphingobium yanoikuyae strain SJTF8 plasmid pF1, complete sequence	476815-476846	9	0.719
NZ_CP046815_1	1.15\|375428\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	375428-375459	32	MH412654	Synechococcus phage S-T4, complete genome	103296-103327	9	0.719
NZ_CP046815_1	1.15\|375428\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	375428-375459	32	NC_001901	Bacteriophage N15, complete genome	36964-36995	9	0.719
NZ_CP046815_1	1.16\|375488\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	375488-375519	32	NZ_CP040897	Enterococcus faecalis strain HA-1 plasmid punnamed	13623-13654	9	0.719
NZ_CP046815_1	1.16\|375488\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	375488-375519	32	NZ_CP046109	Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence	55074-55105	9	0.719
NZ_CP046815_1	1.16\|375488\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	375488-375519	32	NC_011642	Enterococcus faecalis plasmid pMG2200, complete sequence	65367-65398	9	0.719
NZ_CP046815_1	1.16\|375488\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	375488-375519	32	NZ_CP028284	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence	28964-28995	9	0.719
NZ_CP046815_1	1.18\|375608\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	375608-375639	32	NZ_CP042875	Bacillus cereus strain 09 plasmid unnamed1, complete sequence	343999-344030	9	0.719
NZ_CP046815_1	1.19\|375668\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	375668-375699	32	NZ_CP024238	Escherichia coli O15:H11 strain 90-9272 plasmid unnamed	167086-167117	9	0.719
NZ_CP046815_1	1.19\|375668\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	375668-375699	32	NC_013507	Escherichia coli ETEC H10407 plasmid pEntH10407, complete sequence	39023-39054	9	0.719
NZ_CP046815_1	1.19\|375668\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	375668-375699	32	NZ_CP024249	Escherichia coli O182:H21 strain D181 plasmid unnamed1, complete sequence	6880-6911	9	0.719
NZ_CP046815_1	1.19\|375668\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	375668-375699	32	NC_017722	Escherichia coli ETEC H10407 plasmid p666, complete sequence	65951-65982	9	0.719
NZ_CP046815_1	1.1\|374588\|32\|NZ_CP046815\|CRISPRCasFinder,CRT	374588-374619	32	NZ_CP020040	Streptomyces sp. 3211 isolate 3 plasmid p3211-1, complete sequence	489892-489923	10	0.688
NZ_CP046815_1	1.11\|375188\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	375188-375219	32	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	893528-893559	10	0.688
NZ_CP046815_1	1.16\|375488\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	375488-375519	32	NZ_KY362373	Pseudomonas syringae pv. syringae strain 7B44 plasmid pPs7B44, complete sequence	26487-26518	10	0.688
NZ_CP046815_1	1.16\|375488\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	375488-375519	32	NZ_KY362372	Pseudomonas syringae pv. syringae strain UMAF0170 plasmid pPs0170, complete sequence	21500-21531	10	0.688
NZ_CP046815_1	1.16\|375488\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	375488-375519	32	NZ_CP026559	Pseudomonas amygdali pv. morsprunorum strain R15244 plasmid p2_tig3, complete sequence	114243-114274	10	0.688
NZ_CP046815_1	1.16\|375488\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	375488-375519	32	NZ_LT963406	Pseudomonas syringae pv. avii isolate CFBP3846 plasmid PP4, complete sequence	4854-4885	10	0.688
NZ_CP046815_1	1.16\|375488\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	375488-375519	32	CP027480	Pseudomonas koreensis strain P19E3 plasmid p3, complete sequence	174768-174799	10	0.688
NZ_CP046815_1	1.16\|375488\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	375488-375519	32	NZ_CP026564	Pseudomonas avellanae strain R2leaf plasmid p2_tig5, complete sequence	68517-68548	10	0.688
NZ_CP046815_1	1.19\|375668\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	375668-375699	32	AY212251	Streptococcus virus C1, complete genome	10386-10417	10	0.688
NZ_CP046815_1	1.19\|375668\|32\|NZ_CP046815\|CRISPRCasFinder,CRT,PILER-CR	375668-375699	32	NC_004814	Streptococcus phage C1, complete genome	10386-10417	10	0.688

1. spacer 1.2|374648|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to NC_010113 (Vibrio sp. 0908 plasmid p0908, complete sequence) position: , mismatch: 0, identity: 1.0

ctgtcattcatcaaggggcgcgtgggccgcaa	CRISPR spacer
ctgtcattcatcaaggggcgcgtgggccgcaa	Protospacer
********************************

2. spacer 1.2|374648|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP046830 (Vibrio parahaemolyticus strain 2012AW-0224 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

ctgtcattcatcaaggggcgcgtgggccgcaa	CRISPR spacer
ctgtcattcatcaaggggcgcgtgggccgcaa	Protospacer
********************************

3. spacer 1.1|374588|32|NZ_CP046815|CRISPRCasFinder,CRT matches to MH338234 (Mycobacterium phage Crucio, complete genome) position: , mismatch: 6, identity: 0.812

gatatcgtccacgccatcaacgtgctg-gcgat	CRISPR spacer
gccgtcgaccacgcgatcaacgtgctgagcga-	Protospacer
* ..*** ****** ************ ****

4. spacer 1.1|374588|32|NZ_CP046815|CRISPRCasFinder,CRT matches to MH697591 (Mycobacterium phage QueenBeesly, complete genome) position: , mismatch: 6, identity: 0.812

gatatcgtccacgccatcaacgtgctg-gcgat	CRISPR spacer
gccgtcgaccacgcgatcaacgtgctgagcga-	Protospacer
* ..*** ****** ************ ****

5. spacer 1.1|374588|32|NZ_CP046815|CRISPRCasFinder,CRT matches to MT498060 (Mycobacterium Phage FiringLine, complete genome) position: , mismatch: 6, identity: 0.812

gatatcgtccacgccatcaacgtgctg-gcgat	CRISPR spacer
gccgtcgaccacgcgatcaacgtgctgagcga-	Protospacer
* ..*** ****** ************ ****

6. spacer 1.1|374588|32|NZ_CP046815|CRISPRCasFinder,CRT matches to KM463009 (Mycobacterium phage Power, complete genome) position: , mismatch: 6, identity: 0.812

gatatcgtccacgccatcaacgtgctg-gcgat	CRISPR spacer
gccgtcgaccacgcgatcaacgtgctgagcga-	Protospacer
* ..*** ****** ************ ****

7. spacer 1.1|374588|32|NZ_CP046815|CRISPRCasFinder,CRT matches to MT498066 (Mycobacterium phage Georgie2, complete genome) position: , mismatch: 6, identity: 0.812

gatatcgtccacgccatcaacgtgctg-gcgat	CRISPR spacer
gccgtcgaccacgcgatcaacgtgctgagcga-	Protospacer
* ..*** ****** ************ ****

8. spacer 1.1|374588|32|NZ_CP046815|CRISPRCasFinder,CRT matches to MN234203 (Mycobacterium phage SemperFi, complete genome) position: , mismatch: 6, identity: 0.812

gatatcgtccacgccatcaacgtgctg-gcgat	CRISPR spacer
gccgtcgaccacgcgatcaacgtgctgagcga-	Protospacer
* ..*** ****** ************ ****

9. spacer 1.1|374588|32|NZ_CP046815|CRISPRCasFinder,CRT matches to MF919531 (Mycobacterium phage SnapTap, complete genome) position: , mismatch: 6, identity: 0.812

gatatcgtccacgccatcaacgtgctg-gcgat	CRISPR spacer
gccgtcgaccacgcgatcaacgtgctgagcga-	Protospacer
* ..*** ****** ************ ****

10. spacer 1.1|374588|32|NZ_CP046815|CRISPRCasFinder,CRT matches to NC_029043 (Mycobacterium phage SweetiePie, complete genome) position: , mismatch: 6, identity: 0.812

gatatcgtccacgccatcaacgtgctg-gcgat	CRISPR spacer
gccgtcgaccacgcgatcaacgtgctgagcga-	Protospacer
* ..*** ****** ************ ****

11. spacer 1.1|374588|32|NZ_CP046815|CRISPRCasFinder,CRT matches to NZ_HG938356 (Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence) position: , mismatch: 7, identity: 0.781

gatatcgtccacgccatcaacgtgctggcgat	CRISPR spacer
ggtctccgccacgccatgaacttgctggcgac	Protospacer
*.* **  ********* *** *********.

12. spacer 1.1|374588|32|NZ_CP046815|CRISPRCasFinder,CRT matches to NZ_CP031193 (Humibacter sp. BT305 plasmid unnamed1) position: , mismatch: 8, identity: 0.75

gatatcgtccacgccatcaacgtgctggcgat	CRISPR spacer
ggcgctctcctcgccatcatcgtgctggcgat	Protospacer
*..... *** ******** ************

13. spacer 1.11|375188|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to KP010268 (Enterobacteria phage SfMu, complete genome) position: , mismatch: 8, identity: 0.75

cgtagctttttcgcggttggtggctccttcgg	CRISPR spacer
cgtggctttttcgcggtttgtggagccggtcg	Protospacer
***.************** ****  **  . *

14. spacer 1.1|374588|32|NZ_CP046815|CRISPRCasFinder,CRT matches to NZ_CP050096 (Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b3, complete sequence) position: , mismatch: 9, identity: 0.719

gatatcgtccacgccatcaacgtgctggcgat	CRISPR spacer
tgcgccgtccgcaccatcaacgtgctgggcat	Protospacer
 ....*****.*.***************  **

15. spacer 1.1|374588|32|NZ_CP046815|CRISPRCasFinder,CRT matches to NZ_CP033227 (Sphingobium yanoikuyae strain SJTF8 plasmid pF1, complete sequence) position: , mismatch: 9, identity: 0.719

gatatcgtccacgccatcaacgtgctggcgat	CRISPR spacer
cggatcgtgctcgccatcaacgtgctctccac	Protospacer
 . ***** * ***************  * *.

16. spacer 1.15|375428|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to MH412654 (Synechococcus phage S-T4, complete genome) position: , mismatch: 9, identity: 0.719

gggggatgctgctctacatctttatcttcgaa	CRISPR spacer
agccattgctgatcaacatctttatcttctag	Protospacer
.*  . ***** ** ************** *.

17. spacer 1.15|375428|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to NC_001901 (Bacteriophage N15, complete genome) position: , mismatch: 9, identity: 0.719

gggggatgctgctctacatctttatcttcgaa	CRISPR spacer
gcttcgagctgctctacatctgaatcttcgta	Protospacer
*    . **************  ******* *

18. spacer 1.16|375488|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP040897 (Enterococcus faecalis strain HA-1 plasmid punnamed) position: , mismatch: 9, identity: 0.719

ggaaatacgttgaccaccgaaagagcgtgagc	CRISPR spacer
agaaagactttgaccaccgaaagagagaataa	Protospacer
.**** ** **************** * . .

19. spacer 1.16|375488|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP046109 (Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence) position: , mismatch: 9, identity: 0.719

ggaaatacgttgaccaccgaaagagcgtgagc	CRISPR spacer
agaaagactttgaccaccgaaagagagaataa	Protospacer
.**** ** **************** * . .

20. spacer 1.16|375488|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to NC_011642 (Enterococcus faecalis plasmid pMG2200, complete sequence) position: , mismatch: 9, identity: 0.719

ggaaatacgttgaccaccgaaagagcgtgagc	CRISPR spacer
agaaagactttgaccaccgaaagagagaataa	Protospacer
.**** ** **************** * . .

21. spacer 1.16|375488|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP028284 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

ggaaatacgttgaccaccgaaagagcgtgagc	CRISPR spacer
agaaagactttgaccaccgaaagagagaataa	Protospacer
.**** ** **************** * . .

22. spacer 1.18|375608|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP042875 (Bacillus cereus strain 09 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

gccgattttaaatagatatattgaccgtctaa	CRISPR spacer
tataaataaaaaaagatatattgaccgtttaa	Protospacer
  ..* *  *** ***************.***

23. spacer 1.19|375668|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024238 (Escherichia coli O15:H11 strain 90-9272 plasmid unnamed) position: , mismatch: 9, identity: 0.719

ctggtgatttgcctgttcttaaattttcacta	CRISPR spacer
caaatgatttgactgctcttaaattttttatt	Protospacer
* ..******* ***.***********.  *

24. spacer 1.19|375668|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to NC_013507 (Escherichia coli ETEC H10407 plasmid pEntH10407, complete sequence) position: , mismatch: 9, identity: 0.719

ctggtgatttgcctgttcttaaattttcacta	CRISPR spacer
caaatgatttgactgctcttaaattttttatt	Protospacer
* ..******* ***.***********.  *

25. spacer 1.19|375668|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024249 (Escherichia coli O182:H21 strain D181 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

ctggtgatttgcctgttcttaaattttcacta	CRISPR spacer
caaatgatttgactgctcttaaattttttatt	Protospacer
* ..******* ***.***********.  *

26. spacer 1.19|375668|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to NC_017722 (Escherichia coli ETEC H10407 plasmid p666, complete sequence) position: , mismatch: 9, identity: 0.719

ctggtgatttgcctgttcttaaattttcacta	CRISPR spacer
caaatgatttgactgctcttaaattttttatt	Protospacer
* ..******* ***.***********.  *

27. spacer 1.1|374588|32|NZ_CP046815|CRISPRCasFinder,CRT matches to NZ_CP020040 (Streptomyces sp. 3211 isolate 3 plasmid p3211-1, complete sequence) position: , mismatch: 10, identity: 0.688

gatatcgtccacgccatcaacgtgctggcgat	CRISPR spacer
ggccacgtccacgctctcaacgtgctgggtgg	Protospacer
*..  *********. ************  .

28. spacer 1.11|375188|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 10, identity: 0.688

cgtagctttttcgcggttggtggctccttcgg	CRISPR spacer
ctcggctttttcgcggtgggtggttcccgttc	Protospacer
* ..************* *****.***. .

29. spacer 1.16|375488|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KY362373 (Pseudomonas syringae pv. syringae strain 7B44 plasmid pPs7B44, complete sequence) position: , mismatch: 10, identity: 0.688

ggaaatacgttgaccaccgaaagagcgtgagc	CRISPR spacer
aggtgcttcttgaccaccgaaagcgcgtcagc	Protospacer
.*. .. . ************** **** ***

30. spacer 1.16|375488|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KY362372 (Pseudomonas syringae pv. syringae strain UMAF0170 plasmid pPs0170, complete sequence) position: , mismatch: 10, identity: 0.688

ggaaatacgttgaccaccgaaagagcgtgagc	CRISPR spacer
aggtgcttcttgaccaccgaaagcgcgtcagc	Protospacer
.*. .. . ************** **** ***

31. spacer 1.16|375488|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026559 (Pseudomonas amygdali pv. morsprunorum strain R15244 plasmid p2_tig3, complete sequence) position: , mismatch: 10, identity: 0.688

ggaaatacgttgaccaccgaaagagcgtgagc	CRISPR spacer
aggtgcttcttgaccaccgaaagcgcgtcagc	Protospacer
.*. .. . ************** **** ***

32. spacer 1.16|375488|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LT963406 (Pseudomonas syringae pv. avii isolate CFBP3846 plasmid PP4, complete sequence) position: , mismatch: 10, identity: 0.688

ggaaatacgttgaccaccgaaagagcgtgagc	CRISPR spacer
aggtgcttcttgaccaccgaaagcgcgtcagc	Protospacer
.*. .. . ************** **** ***

33. spacer 1.16|375488|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to CP027480 (Pseudomonas koreensis strain P19E3 plasmid p3, complete sequence) position: , mismatch: 10, identity: 0.688

ggaaatacgttgaccaccgaaagagcgtgagc	CRISPR spacer
aggtgcttcttgaccaccgaaagcgcgtcagc	Protospacer
.*. .. . ************** **** ***

34. spacer 1.16|375488|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026564 (Pseudomonas avellanae strain R2leaf plasmid p2_tig5, complete sequence) position: , mismatch: 10, identity: 0.688

ggaaatacgttgaccaccgaaagagcgtgagc	CRISPR spacer
aggtgcttcttgaccaccgaaagcgcgtcagc	Protospacer
.*. .. . ************** **** ***

35. spacer 1.19|375668|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to AY212251 (Streptococcus virus C1, complete genome) position: , mismatch: 10, identity: 0.688

ctggtgatttgcctgttcttaaattttcacta	CRISPR spacer
gtggtgatttgtctgttcgtaaattaggtaag	Protospacer
 **********.****** ******      .

36. spacer 1.19|375668|32|NZ_CP046815|CRISPRCasFinder,CRT,PILER-CR matches to NC_004814 (Streptococcus phage C1, complete genome) position: , mismatch: 10, identity: 0.688

ctggtgatttgcctgttcttaaattttcacta	CRISPR spacer
gtggtgatttgtctgttcgtaaattaggtaag	Protospacer
 **********.****** ******      .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

651181 : 657770

Staphylococcus_phage(66.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_078925467.1\|651181_651652_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	2.9e-32	48.7
WP_078925468.1\|651842_652952_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	2.0e-60	39.0
WP_078925469.1\|653009_653666_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	2.2e-30	36.1
WP_078925471.1\|653677_654778_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	2.6e-44	33.8
WP_078925473.1\|654792_655242_-	transcriptional regulator NrdR	NA	NA	NA	NA
WP_078925475.1\|655374_656625_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.7e-95	48.5
WP_115174046.1\|656636_657770_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.5e-66	42.9

DBSCAN-SWA_2

1748558 : 1809229

Staphylococcus_phage(22.22%)

transposase,integrase

attL 1782971:1782986|attR 1809561:1809576

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_115174026.1\|1748558_1749355_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_078926586.1\|1749426_1750161_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_078926587.1\|1750395_1751982_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_078926588.1\|1752047_1753373_+	6-phospho-alpha-glucosidase	NA	NA	NA	NA
WP_078926589.1\|1753590_1754733_+	glycerate kinase	W6LM47	Streptococcus_phage	2.0e-42	37.7
WP_000273139.1\|1755517_1755739_+	hypothetical protein	NA	NA	NA	NA
WP_078926590.1\|1755900_1756128_-	hypothetical protein	NA	NA	NA	NA
WP_078926591.1\|1756175_1756544_-	hypothetical protein	NA	NA	NA	NA
WP_078926592.1\|1756573_1757308_-	transcriptional regulator	NA	NA	NA	NA
WP_115174025.1\|1757446_1757623_-	hypothetical protein	NA	NA	NA	NA
WP_078926593.1\|1757875_1760881_-\|transposase	Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	68.5
WP_016151372.1\|1760964_1761264_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_016151373.1\|1761256_1761499_-	type II toxin-antitoxin system ParD family antitoxin	NA	NA	NA	NA
WP_078926594.1\|1761694_1762330_+	serine recombinase	NA	NA	NA	NA
WP_078926595.1\|1762834_1763494_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_078926596.1\|1763490_1764807_+	HlyD family secretion protein	NA	NA	NA	NA
WP_078926597.1\|1764803_1767905_+	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_078926598.1\|1768273_1769797_-\|transposase	ISNCY family transposase	A0A0M3LS26	Mannheimia_phage	5.5e-08	31.0
WP_078926599.1\|1770156_1770462_-	monooxygenase	NA	NA	NA	NA
WP_078926600.1\|1770611_1771505_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_078926601.1\|1771743_1772130_-	RidA family protein	NA	NA	NA	NA
WP_078926602.1\|1772191_1773523_-	D-serine ammonia-lyase	NA	NA	NA	NA
WP_078926603.1\|1773535_1774873_-	D-serine transporter DsdX	NA	NA	NA	NA
WP_078926604.1\|1775094_1776030_+	DNA-binding transcriptional regulator DsdC	NA	NA	NA	NA
WP_115174024.1\|1777002_1777446_-	DUF2787 domain-containing protein	NA	NA	NA	NA
WP_031852557.1\|1777436_1777910_-	DNA repair protein RadC	NA	NA	NA	NA
WP_078926607.1\|1778115_1779138_-	DUF4238 domain-containing protein	NA	NA	NA	NA
WP_032468702.1\|1779480_1779939_+\|transposase	IS200/IS605 family transposase	I4AZI8	Saccharomonospora_phage	2.0e-14	33.1
WP_078927315.1\|1780048_1780993_-	hypothetical protein	NA	NA	NA	NA
WP_078927316.1\|1781600_1784210_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	3.1e-91	40.9
1782971:1782986	attL	NA	NA	NA	NA
WP_078927317.1\|1784211_1785495_+	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	6.1e-08	24.0
WP_078927318.1\|1785507_1789344_+	type I restriction endonuclease subunit R	NA	NA	NA	NA
WP_078927319.1\|1789493_1790498_-	hypothetical protein	A0A0R6PIZ6	Moraxella_phage	9.1e-44	33.3
WP_078927320.1\|1790845_1792087_-\|integrase	tyrosine-type recombinase/integrase	A0A1V0E8G8	Vibrio_phage	2.0e-109	47.3
WP_078927321.1\|1792617_1794441_-	AAA family ATPase	NA	NA	NA	NA
WP_139364791.1\|1794430_1794877_-	hypothetical protein	NA	NA	NA	NA
WP_078927323.1\|1794873_1795941_-	hypothetical protein	NA	NA	NA	NA
WP_078927324.1\|1796889_1797552_-	hypothetical protein	NA	NA	NA	NA
WP_060658345.1\|1797720_1797966_-	hypothetical protein	NA	NA	NA	NA
WP_078927325.1\|1798066_1799158_-	P-type conjugative transfer protein TrbL	NA	NA	NA	NA
WP_078927327.1\|1799351_1800128_-	P-type conjugative transfer protein TrbJ	NA	NA	NA	NA
WP_078927328.1\|1800157_1801930_-	relaxase/mobilization nuclease domain-containing protein	NA	NA	NA	NA
WP_078927329.1\|1801935_1802298_-	conjugal transfer transcriptional regulator TraJ	NA	NA	NA	NA
WP_078927330.1\|1802638_1802983_-	TraK family protein	NA	NA	NA	NA
WP_078927331.1\|1802984_1803224_-	plasmid-related protein	NA	NA	NA	NA
WP_078927332.1\|1804161_1805115_+	toll/interleukin-1 receptor domain-containing protein	NA	NA	NA	NA
WP_078927333.1\|1805201_1806032_+	hypothetical protein	NA	NA	NA	NA
WP_078927334.1\|1806079_1807126_-	HipA domain-containing protein	NA	NA	NA	NA
WP_078927335.1\|1807109_1807436_-	hypothetical protein	NA	NA	NA	NA
WP_078927336.1\|1807420_1807741_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_078927337.1\|1808137_1809229_-\|integrase	site-specific integrase	W6MYA3	Pseudomonas_phage	7.4e-47	38.2
1809561:1809576	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1820560 : 1827710

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_078927348.1\|1820560_1821316_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	2.4e-65	51.4
WP_078927349.1\|1821320_1821947_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	1.5e-36	49.7
WP_078927350.1\|1821946_1822894_+	murein hydrolase activator NlpD	I2E8W3	Clostridium_phage	6.2e-10	33.1
WP_078927351.1\|1822960_1823950_+	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	1.5e-35	34.6
WP_078927352.1\|1824013_1826596_-	DNA mismatch repair protein MutS	A0A1V0SJ67	Klosneuvirus	7.9e-31	25.4
WP_078927353.1\|1826819_1827710_-	cysteine synthase CysM	A0A1X9I5F1	Streptococcus_phage	4.0e-59	42.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP046816

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046816_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046816_1

164907-165052

Orphan

Consensus_repeat	Method
AATGACAATAAAGTTTGAAACTTTT	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP046816_1

>merge|NZ_CP046816|1|164907-165052|PILER-CR
AAGGACATTAAAGTTTGAAACTTTTCTATCCTGTAAGGTTTAATACCAAGTAGCTCTAGATACAAAAAGTGACAATAAAGTTTGAAACTAAATTGATCAATAACCTTCTGTACAACAGAATTATGACAGTAAAGTTTGAAACTTTT

>NZ_CP046816|1|1|164907-165052|PILER-CR
AAGGACATTAAAGTTTGAAACTTTT	CTATCCTGTAAGGTTTAATACCAAGTAGCTCTAGATACAAAA
AGTGACAATAAAGTTTGAAACTAAA	TTGATCAATAACCTTCTGTACAACAGAATTAT
GACAGTAAAGTTTGAAACTTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046816.1\|WP_078925062.1\|159696_160425_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP046816.1\|WP_078925065.1\|156523_157705_-\|amidase	unknown	unknown	gnl\|CDD\|181375
NZ_CP046816.1\|WP_139364770.1\|165693_166254_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225418
NZ_CP046816.1\|WP_139364769.1\|173228_173639_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_115173913.1\|170021_171755_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|379862
NZ_CP046816.1\|WP_078925061.1\|160411_161062_-\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_CP046816.1\|WP_078925067.1\|152411_153647_-\|allantoate-amidohydrolase	unknown	unknown	gnl\|CDD\|349880
NZ_CP046816.1\|WP_078925066.1\|154919_156512_-\|gamma-glutamyltransferase-family-protein	unknown	unknown	gnl\|CDD\|223482
NZ_CP046816.1\|WP_078925060.1\|161074_161743_-\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_CP046816.1\|WP_078925064.1\|157803_158817_-\|bile-acid:sodium-symporter	unknown	unknown	gnl\|CDD\|372642
NZ_CP046816.1\|WP_078925063.1\|158858_159677_-\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
NZ_CP046816.1\|WP_078925053.1\|171744_173136_-\|TolC-family-protein	unknown	unknown	gnl\|CDD\|224455
NZ_CP046816.1\|WP_078925052.1\|173716_175036_-\|heavy-metal-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|273593
NZ_CP046816.1\|WP_078925058.1\|163227_164448_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|170049
NZ_CP046816.1\|WP_078925050.1\|175746_176088_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_078925051.1\|175032_175716_-\|heavy-metal-response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|130454
NZ_CP046816.1\|WP_078925059.1\|162656_162932_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_078925055.1\|166896_170022_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|226220
NZ_CP046816.1\|WP_074374971.1\|165233_165674_-\|CopG-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225564
NZ_CP046816.1\|WP_078925056.1\|166272_166827_-\|copper-binding-protein	unknown	unknown	gnl\|CDD\|259873

Protein	Function_ID	Function_description	E-value
NZ_CP046816.1\|WP_078925062.1\|159696_160425_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	4.27715e-148
NZ_CP046816.1\|WP_078925065.1\|156523_157705_-\|amidase	gnl\|CDD\|181375	PRK08310, PRK08310, amidase; Provisional.	7.56951e-124
NZ_CP046816.1\|WP_139364770.1\|165693_166254_-\|hypothetical-protein	gnl\|CDD\|225418	COG2863, COG2863, Cytochrome c553 [Energy production and conversion].	1.1619e-05
NZ_CP046816.1\|WP_115173913.1\|170021_171755_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|379862	pfam16576, HlyD_D23, Barrel-sandwich domain of CusB or HlyD membrane-fusion. HlyD_D23 is the combined domains 2 and 3 of the membrane-fusion proteins CusB and HlyD, which forms a barrel-sandwich. CusB and HlyD proteins are membrane fusion proteins of the CusCFBA copper efflux system in E.coli and related bacteria. The whole molecule hinges between D2 and D3. Efflux systems of this resistance-nodulation-division group - RND - have been developed to excrete poisonous metal ions, and in E.coli the only one that deals with silver and copper is the CusA transporter. The transporter CusA works in conjunction with a periplasmic component that is a membrane fusion protein, eg CusB, and an outer-membrane channel component CusC in a CusABC complex driven by import of protons.	2.84075e-100
NZ_CP046816.1\|WP_078925061.1\|160411_161062_-\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	3.48184e-72
NZ_CP046816.1\|WP_078925067.1\|152411_153647_-\|allantoate-amidohydrolase	gnl\|CDD\|349880	cd03884, M20_bAS, M20 Peptidase beta-alanine synthase, an amidohydrolase. Peptidase M20 family, beta-alanine synthase (bAS; N-carbamoyl-beta-alanine amidohydrolase and beta-ureidopropionase; EC 3.5.1.6) subfamily. bAS is an amidohydrolase and is the final enzyme in the pyrimidine catabolic pathway, which is involved in the regulation of the cellular pyrimidine pool. bAS catalyzes the irreversible hydrolysis of the N-carbamylated beta-amino acids to beta-alanine or aminoisobutyrate with the release of carbon dioxide and ammonia. Also included in this subfamily is allantoate amidohydrolase (allantoate deiminase), which catalyzes the conversion of allantoate to (S)-ureidoglycolate, one of the crucial alternate steps in purine metabolism. It is possible that these two enzymes arose from the same ancestral peptidase that evolved into two structurally related enzymes with distinct catalytic properties and biochemical roles within the cell. Downstream enzyme (S)-ureidoglycolate amidohydrolase (UAH) is homologous in structure and sequence with AAH and catalyzes the conversion of (S)-ureidoglycolate into glyoxylate, releasing two molecules of ammonia as by-products. Yeast requires beta-alanine as a precursor of pantothenate and coenzyme A biosynthesis, but generates it mostly via degradation of spermine. Disorders in pyrimidine degradation and beta-alanine metabolism caused by beta-ureidopropionase deficiency (UPB1 gene) in humans are normally associated with neurological disorders.	6.49667e-161
NZ_CP046816.1\|WP_078925066.1\|154919_156512_-\|gamma-glutamyltransferase-family-protein	gnl\|CDD\|223482	COG0405, Ggt, Gamma-glutamyltransferase [Amino acid transport and metabolism].	2.11084e-149
NZ_CP046816.1\|WP_078925060.1\|161074_161743_-\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	5.92404e-72
NZ_CP046816.1\|WP_078925064.1\|157803_158817_-\|bile-acid:sodium-symporter	gnl\|CDD\|372642	pfam13593, SBF_like, SBF-like CPA transporter family (DUF4137). These family members are 7TM putative membrane transporter proteins. The family is similar to the SBF family of bile-acid symporters, pfam01758.	5.44413e-107
NZ_CP046816.1\|WP_078925063.1\|158858_159677_-\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	8.07308e-39
NZ_CP046816.1\|WP_078925053.1\|171744_173136_-\|TolC-family-protein	gnl\|CDD\|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	1.56506e-17
NZ_CP046816.1\|WP_078925052.1\|173716_175036_-\|heavy-metal-sensor-histidine-kinase	gnl\|CDD\|273593	TIGR01386, Probable_sensor_protein_PcoS, heavy metal sensor kinase. Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.	2.1902e-105
NZ_CP046816.1\|WP_078925058.1\|163227_164448_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|170049	PRK09692, PRK09692, integrase; Provisional.	7.93225e-115
NZ_CP046816.1\|WP_078925051.1\|175032_175716_-\|heavy-metal-response-regulator-transcription-factor	gnl\|CDD\|130454	TIGR01387, Transcriptional_regulatory_protein_PcoR, heavy metal response regulator. Members of this family contain a response regulator receiver domain (pfam00072) and an associated transcriptional regulatory region (pfam00486). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc. Most members encoded by genes adjacent to genes for encoding a member of the heavy metal sensor histidine kinase family (TIGRFAMs:TIGR01386), its partner in the two-component response regulator system. [Regulatory functions, DNA interactions].	1.12259e-97
NZ_CP046816.1\|WP_078925055.1\|166896_170022_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|226220	COG3696, COG3696, Putative silver efflux pump [Inorganic ion transport and metabolism].	0
NZ_CP046816.1\|WP_074374971.1\|165233_165674_-\|CopG-family-transcriptional-regulator	gnl\|CDD\|225564	COG3019, COG3019, Predicted metal-binding protein [General function prediction only].	2.8091e-47
NZ_CP046816.1\|WP_078925056.1\|166272_166827_-\|copper-binding-protein	gnl\|CDD\|259873	cd04211, Cupredoxin_like_2, Uncharacterized Cupredoxin-like subfamily. Cupredoxins contain type I copper centers and are involved in inter-molecular electron transfer reactions. Cupredoxins are blue copper proteins because they have an intense blue color due to the presence of a mononuclear type 1 (T1) copper site. Structurally, the cupredoxin-like fold consists of a beta-sandwich with 7 strands in 2 beta-sheets, which is arranged in a Greek-key beta-barrel. Some of these proteins have lost the ability to bind copper. Majority of family members contain multiple cupredoxin domain repeats; ceruloplasmin and coagulation factors V/VIII have six repeats; Laccase, ascorbate oxidase, and spore coat protein A, and multicopper oxidase CueO contain three repeats; and nitrite reductase has two repeats. Others are mono-domain cupredoxins, such as plastocyanin, pseudoazurin, plantacyanin, azurin, rusticyanin, stellacyanin, quinol oxidase and the periplasmic domain of cytochrome c oxidase subunit II.	3.56255e-47

>NZ_CP046816.1|WP_078925058.1|163227_164448_+|tyrosine-type-recombinase/integrase
MAKRITDTTIKALVIKDKEYTYTVEEGLQLRIRPKRSDKGTGTKAWQFKYRHPVTRKITKIPMGTYPSLRLAAAKLEAAEYRKQIAEGIDPKRFKEDKRIEELRKHNDNFLEVSTMWFDRKRKSVSSFHAERIWRTLEKYVFDSLGDLPVSNITRRDAIEMLRPLEKDGKLSTIKRICQSLNQIMEYAVASDVINANPLTKMINSFEKHKVENMPTIRPELLGEFMTRLRQNENIQDKTKLLLLWQLHTISRPKEAARTRWKDIDFNKQCWTIPAEEMKRRREHRVPLTKQAIDILEKIKVQSIGKEFVFPSERNPDSHVSVYTANAALKRSLGFKDELVAHGLRAIASTALHEQGFDTLHIEACLSHMDKNVTRASYNRSDFFEQRKEIMSWWSEFITKAKAQDS
>NZ_CP046816.1|WP_078925059.1|162656_162932_-|hypothetical-protein
MNLIGEPYQISHNDSRSYSVHFSIFIMVRESACFNVSTIKLGGDLPSDGQLYTEAVISINETGTIAPTLVISAPKVSQGQSSVRWGNYDWL
>NZ_CP046816.1|WP_078925060.1|161074_161743_-|amino-acid-ABC-transporter-permease
MSYQLNFSGLTPYLPQFVAGLGTTVELTVISTFGGLLLGTLCASAKTSQAKWLKFVCTCYIEVIRNTPFIVQLFFIFFGLPALGIKFSAWQAGVIAMVINLGAYSAEIIRAGIEATPKGQWEAGKTLGLTRMQIFTRIVISPAYQRVYPAIVSQCIIVMLGSAVVSQISVEDLTFAANFVQSRSFLSFESYMLTAAIYLVLAIVMRQVFALIKHVVFKNPSL
>NZ_CP046816.1|WP_078925061.1|160411_161062_-|amino-acid-ABC-transporter-permease
MMQFTDWDIFRSLLMAARWTVALSLIAFVSGGLLGLFITLLRSTRHSVFTGLIKLYVELFQGTPLLMQLFLAFFGLSLAGVEVSAWTAAVLSLTLFSSAFFHDIWRGCIESLPKGQWEACRTLGLTHMQTMRYIIAPQAARLAIAPTVGFSVQIVKGTALASIIGFVELTKAGTMLNNATFQPFKVFALVALLYFVICFPLSALARYLEARNHVTR
>NZ_CP046816.1|WP_078925062.1|159696_160425_-|amino-acid-ABC-transporter-ATP-binding-protein
MSLVSVEQVHKYYGENHVLKGIDLKINPGEVVSIIGRSGSGKSTLLRCMNGLEDYQDGVIIVDNQAVENDDYKLRLLSRSVGMVFQNFNLFPHLTVGENVMLAPKLVLKKSAKECEALARELLEKVGLADKFDAYPTNLSGGQQQRVAIARSLAMNPKVLLCDEITSALDPELVGEVLRVLEQLKAEGMTLILVTHEMNFARDVGDRVVFMNQGKVWESGPSESVFISPQTPELQSFLSAVR
>NZ_CP046816.1|WP_078925063.1|158858_159677_-|MurR/RpiR-family-transcriptional-regulator
MTNNHHSLSERITQQYSRLTESSRRIADYLQLNPEKILMLSTAEIAESCSVSKTSVSRFIRQLGYDDHVALRQELMQEREKGIPVLTSHIEDLDIQHDMRALEQLCLQLATLDVTELVDAMVKAKRVKIIGYRNSYPLAMHFRQQLMQCRANVELLPLPGQTLGEDLVSITDDDFVIVIGIRRRISQFEKIIHHLNGKPSLLITDQSGQKYAGLVKHFLVCHMNNQAPLDSYAVPMSLVSYLVNKVYRHLGEKATKLSRHISKNYAQLNEVE
>NZ_CP046816.1|WP_078925064.1|157803_158817_-|bile-acid:sodium-symporter
MNVLAKLKKEWFLVGMLIAIVLATVTSEFGRSDGVIHLDQLTGVGIAIVFFLHGLGLSPQAIKAGVTNWRLHVYIQMATFVVYPILWVIFGETFLAYMPSALAFGFCYLLVLPSTISSSVAMTSVGKGNVPGAIFNASLSSILGVFITPLLIQLFMGFEGVQLDLLDSVVSISELLLVPMIAGQIMRPYLVTWVERHKALVNKVDKYVILLIVYNAFCDSVVNGIWSEFSVGLLATSILICTVILLVMVHLIQWGARFTKFALPDEVAAVFCGTKKTLAAGIPMAKVIFGADPALGMVLLPIMLYHPIQIFYCALLANRYARQSESLKTVTHSSAPN
>NZ_CP046816.1|WP_078925065.1|156523_157705_-|amidase
MSKDTRIYCSQGPDTLPAMAQGTLSGTRFVFKDLFDVKGYATGAGNPIWLKSHELATATSPLITALLRQGAECVGRVQTDELAYSLNGQNVHYGTPINPRATECIPGGSSSGSAVAVAAGDCDFSIGTDTGGSVRVPASYCGLFGLRPTLGALDLSHCFELAKSFDTAGIFTRDLRLMRDVWSVLAARSQFGERVTRVYLDAQCQTVMSSARFERFTQQCQGAGIEIVQSHFLAESGWQLAELSLLFRTIQGFEIIVHHDAWLTLYGDSLDPAIWERVQWARTITYEQYQHAKAQQQDFQQQLLTHLKQQHCLWAIPTAPSGPPSLMMPADELAAYRSQLVGLTSIAGLSGLPQLHLPMEALLEGPCGISLMGLPHQEESLLVTGEAVYSGQC
>NZ_CP046816.1|WP_078925066.1|154919_156512_-|gamma-glutamyltransferase-family-protein
MKHQTAFTAPHFKATQVGQQILDAGGTASEAMVAAAAMIAVQYPHMNSIGGDSFWLIAKAGQTPIAIDGCGAAALNVEVEHYRALGDELPFSGGESAITMAGTISAWQKALEVDAGTLTLKTLLQPAMDAARKGIEVTQSLASASEKTFDRLASQQAFAQNFLKQGKTLNIGDTLVNEALANTLQQLAEHGLDAFYRGEIADLVAKELQSAGSPLTLDDFHNHQAKVMAPLTVNTSKGRLYNFGAPTQGVASLLILAIYDRLASQAKSEVDHIHLLVEATKQAFIIRDREVCDEELLSLPLQEWLSDSVIEQCVQNVSMRKASPWPYQAKPGDTVWMGASDQYGTMVSFIQSVYWEFGSGVFLPETGILWNIRSKSFSLDARHHNVLAPGKKPFHTLNPAYAELIDGRRMSYGTMGGEGQPQTQACLFSRYHYQNFSLSNAIAAPRWLLGRTWGNNTNNLRLEQSLYDQYGDALKQRGHEVTFVADCNELMGHAGAIILDSHGKACATSDPRSDGTCLLGEYHDHPKRII
>NZ_CP046816.1|WP_078925067.1|152411_153647_-|allantoate-amidohydrolase
MTVEKDTMARQAKKLMDQADTLAQFSADEDAITRAYLTPQHRAAHDQLAQWMREAGLETWQDSVGNQWGRKVSANPIQSTLILGSHSDTVTNAGKYDGNLGVILAIETLALLVDEAFPFHIDVVAFADEEGTRFNTTLIGSSGVAGCFNPQWLDVKDADGISMAAAMRSFGLDPSLAGSDARTPEETLAYLEVHIEQGPVLEAENLPVGVVTGIAGAKRFQCQVKGIAGHAGTVTLDLRHDALCGAAEMIMAIETFAQQNGIVATVGKCEVLPGAVNVIPGETHFTIDIRSLSQVTLEQCSVELLAQLADIAHRRNLSFDYENIYQAEAVLCSDQLQRQWAEVVESVTQNSPRFLPSGAGHDGLAMTNLTEIGMLFVRCEKGISHNPREQVMEADVLVALNCFVQMVKSFR
>NZ_CP046816.1|WP_074374971.1|165233_165674_-|CopG-family-transcriptional-regulator
MSKNLRLIALSSLILSFNVFAKPVIELYKSPTCGCCKEWAAIMEKKGYEVNVNHARDWSDVKQEFGMPNQLMSCHTAVIGGYMIEGHVPESDIKRLLEERLENISGIAAPGMPQHSPGMARPGQEYKGFNVVSFDKTGHMKLYNKY
>NZ_CP046816.1|WP_139364770.1|165693_166254_-|hypothetical-protein
MMLKRLFMLAGMFSVSLFTYASEDSISAGESTFRTVGGYGCIACHGLYGQGGGNVGGNIRGNSLNDLKYSLEHEQTMKLLGDALSEQDKINLAEYMEYLGTFQLVDWMYEGTKGALLSVSIDSGKKSQLVVLNKMFESMSIDLSPLAGKHLTLRVEPYETQYFEWLPEKGVYELSYGDEAVSINVK
>NZ_CP046816.1|WP_078925056.1|166272_166827_-|copper-binding-protein
MKKVLLATLFSVTSMSVMAGMDHSNMDHGSMNHADMDSSNMNHGDMDHSQMSNSMMSMEGMSDVGMPATGAKPDKVVHVVLADDMTIKFKKEVQIEPNDVVQFVVMNVGKIDHEFTIGSAKEQLEHREMMKKMPHHMHDSGNAVTVKPGKAKQLIWHFHGDSKVEFACNIPGHAEAGMIKKVSL
>NZ_CP046816.1|WP_078925055.1|166896_170022_-|efflux-RND-transporter-permease-subunit
MIGAIIRWSINNRFLVLVATFALVFGGLYSVKNTPVDALPDLSDVQVIIKTSYPGQAPQVVEDQVTYPLTTAMLAVPGAETVRGYSFFGDSYVYIIFNDKTDMYWARSRVLEYLSQVAPNLPPSAKPTLGPDATGVGWIYNYVLQDKTGKHDLAELRSLQDWFLKYELQTVDGVSEVATVGGMVKQYQVQIDPAKLRAYDLTLQQVNMAIQNGNQESGASVVEVAEAEHMVRTTGYLSSIDDIKALPLKVSKKGTPLLLGDVADIDLGPQMRRGISELNGEGEAVGGVIVMRFGENASEVINNVKDKLNELQGSLPDGVEIVATYDRSTLINAAVENLWKKLAEEFIVVAIVCALFLFHIRSSLVIALSLPVGILGAFIVMHWQGINANIMSLGGIAIAIGAMVDGAIVMIENVHKHIERTPLTDKNRWQVIGDAAQEVGAPLFFSLLIITLSFVPVFALEGQEGKMFSPLAFTKTYAMAAAAGLAITLVPVLMGYLVRGKILPENKNPINKGLIALYKPLLNISLKHPKSMIVLAIALMGSAYYPTMKLGSEFIPPLDEGDLMYMPTTYPGISIGKARELLQQTNKLIKTVPEVQTTWGKVGRADTATDPAPLTMIETVIQLKPRDQWREGVTTESLRKEFDDLIQFPGLTNAWVMPIKTRIDMLSTGIKTPIGIKIAGSDLAEIEKIGAQLEPILNNITGTASVYAERVAGGRYVTIDINRKAAARYALSIKEIQQVVSTAVGGMNIGETIEGLERYPINVRYPQGYRDSVVKLQQLPLVTPSGARIALVDVADIRYEDGPPMIKTENARPNGWVFVDIDGRDLGSYVQEAKQAVAEQLDMPAGYSLAWSGQYEYMERAKERLGVVVPITIAIIMLLLYFSFRRVGEVMIIMLTLPLAMVGGLWLMHYLGYNFSIAVGVGFIALAGVAVEIGVIMLVYLNQAWHYTKLDAKEQNKSLSEDDLSHSIQEGAGLRVRPVMMTVLTVIIGLIPIMYGEGTGSEVMQRIAAPMIGGMASALLLTLLVLPAIFKLWKIRELKRN
>NZ_CP046816.1|WP_115173913.1|170021_171755_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MNNNKGIKMSTFKVASLALLIGSALGYGANIYLSGMNYNMVGMTASESKSSDEPLYWVAPMDPNYQRDKPGKSPMGMDLIPVYADDLNGSNDKPGTVKIDPAVENNLGVKTDTVKQEVLAPRIETVGYVAFDESQLWQTNVRVSGWVEKLYINAVGEKVNQGDTLFTLYSPELVKAQEELISAYKTQRKGMIQGATDRLITLGVDRNQIKSIARRGKASQSIEIKAPADGVIASLNIREGGYLSPAQAVISAGPLNQVWVDAEVFERQSHWIKQGSQASMTLDALPGGEWNGEVDYVYPILDPSTRTLRVRLRFDNPQGELKPNMFANVALKPVSSDEVLTIPRSSVIRSGGMTRVVLAEGDGKYRSARIEVGRESADKIEVLKGLQQGERVVTSAHFMLDSESSQSADLSRINGVEPTAETAWATGEITDVMAGHRMLTINHKPVPEWDWPRMTMNFMVSENVEMDQLSKGQTIDFEMQKSESGQYEVVDYKVKELSIDTELWVDGNISMLMADFGMVTLNHLPVADWSWDAGELNFSVGGDFELSGFQEGDKVRFLVEKQGSDYLLKELVKSEDK
>NZ_CP046816.1|WP_078925053.1|171744_173136_-|TolC-family-protein
MSIELNGFRAFKSLSLGVAIALYAMPALSHSGSNATPQTIAASTQQLNALIEAALANDTSRSQYAAQSQAMRETGVASSTLMDPKLKVGFGGLPVDSFKFDEDPMTNISVGLMQQFERGATLDLNQRKANQQADGMAYQVQVREREVANSITQLWLELGYLQYAETLIESNQRLMVEMEQYIQTNYSIGKSEAQDLLNTQLQVNKLDEKLQSNQQMQNRVVAQLSEWLGSEWLNRRSIDSNQAGYQLDWSHLNALLDQQTSDTQYYMLLNQHPMSQIAEANILANRTQVEVVEQAYTPQFGVEVMYAYRQANNMMGEPASDLLSAYLTMDIPLFTDNRQDKNLAAAQYQVGAAQYQKDTLLAQMNAQVVALMTDRENLAERIERYRSRLIPQSKARIEAVERGYQNNTAQFGDVITASTDELALQMELARLITDMNQVNSKLSMLLGGFEYKVSAPNTQYNEQ
>NZ_CP046816.1|WP_139364769.1|173228_173639_-|hypothetical-protein
MTNSLRQTSILIISILAMLMSSYVSSMPMMDMSPISTSSVQPSNHDSMEMSETTASHYAMIGCPSMEVTKSDSSIHCDSSSTSGGDCCKSVCTSVFFPLSSSRLISTSESDLALRHPIKIGVTVTRIQSLLRPPSV
>NZ_CP046816.1|WP_078925052.1|173716_175036_-|heavy-metal-sensor-histidine-kinase
MKELLNQSIARKLVFMFVTASFVVLVVFALTIQNAIKSHFNEQDYSHLETKLRPLTGTIEQDLDLFNSLDISAWILNNRQVVKTNNETIDFPPELIGDSSFEWSVDNKHYQAFKFDYPDTEGGAIVLAMDVTHHKLFFDKLNTILLWTLVLTVILSGAYALIIVRNGLLPLKTLKGYIERVNTSNLSIRIPSNSLPNELSSLIISQNEMLDRLQEGFLRLSEFSSDIAHELRTPLNNIMTQTQVTLGLERSIEEYQDILVSNLEELGRFNKTISDTLYLAKSENKLLHKIEEMLDLKEVITPLLEYYEVLAEEKNVRFTFDGSSILLGDKDMLQRAFGNVLSNALRHCFHNTEISVVITESETTNTVTISNIGEPISTGSLPYIFKRFYRSDKSRVHNGSVGAGLGLPIAKAIMKAHNGDILVNAKDERSEFVFIFNNL
>NZ_CP046816.1|WP_078925051.1|175032_175716_-|heavy-metal-response-regulator-transcription-factor
MKLLVVEDEEKAGAYLKKGLIESGYTVDLSTDGVDALYLATTNDYDLIVLDIMLPKLNGWQLLQTLRSSEIPTPVIILSAKDQVEDRVKGLELGANDYLVKPFAFVELLARVKNALRHQTTTVKTESVLCIADLSLDLLKRKATRNNDTIPLTAKEFSLLEYLFTKRGQVVTRTQIASAVWDMNFDSDTNVIDAAVKRLRSKIDKPYQKKLILTVRGMGYKLDDAVE
>NZ_CP046816.1|WP_078925050.1|175746_176088_-|hypothetical-protein
MIDKISVIFQDQKLEDIESVLAEEGVRNFTIYQVQGRGSYANLIDTHALNTHYQLDVFIGHSHTQILVGALLDTLCVSQEGNGVTSVIENVLLFDNNTKNQISNPSYNHKLDV

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Crispr_ID: NZ_CP046816_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046816_2

289657-290705

Orphan

I-F

Consensus_repeat	Method
TTTCTAAGCTGCCTATGCGGCAGTGAAC	PILER-CR
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CRISPRCasFinder
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CRT

17 spacers

The CRISPR arrays of NZ_CP046816_2

>merge|NZ_CP046816|2|289657-290705|PILER-CR,CRISPRCasFinder,CRT
TTTCTAAGCTGCCTATGCGGCAGTGAACATCAAAAAAACGAGGTCACGTTCCCAGTTCCCTTTCTAAGCTGCCTATGCGGCAGTGAACTACGATGCCGTCCAAGAGGGAATCTTGATGTTTTTCTAAGCTGCCTATGCGGCAGTGAACGCCGCGCTTCATGTAACGCATTGACTAATCTATTTCTAAGCTGCCTATGCGGCAGTGAACCGGCGCGAAAAAAGTTTCGAGAGGGCTTAAACTTTCTAAGCTGCCTATGCGGCAGTGAACTTGTTGCTAATCGCATAAGGCGCTTGCATTCCTTTCTAAGCTGCCTATGCGGCAGTGAACTCTACTGAGTGAGTGACGACTTCTTCGGTAATTTTCTAAGCTGCCTATGCGGCAGTGAACTATTCACTCATGCTGGCTTCGTTGCCCAAGACTTTCTAAGCTGCCTATGCGGCAGTGAACATCGAGTGGCGAATTTATCGCTATTGCCGAGCTTTCTAAGCTGCCTATGCGGCAGTGAACAAGGCATTGCGGAGTATTTGCTTGTTGGTGAGTTTCTAAGCTGCCTATGCGGCAGTGAACAAAGCCATAATTAAAACCACCCTTCTTTTTTATTTTCTAAGCTGCCTATGCGGCAGTGAACGTGACGTTCAAAATAAACCGGACGTTTTTTAGTTTCTAAGCTGCCTATGCGGCAGTGAACTCACCACGGTAATCACTATCAATCACACCAATTTTCTAAGCTGCCTATGCGGCAGTGAACAAGCAATATCAACACGAGTAATTTTAACCGAATTTCTAAGCTGCCTATGCGGCAGTGAACATACTAAATATGGTCAAACTATTGCCCTTGCTTTTCTAAGCTGCCTATGCGGCAGTGAACGATATGGGTTATCACGCGAGCTTGGCGAATCGTTTCTAAGCTGCCTATGCGGCAGTGAACAAAATGGTAGCGGCTCCGCTTCGTTTGCTTTTTTTCTAAGCTGCCTATGCGGCAGTGAACCAGAAGTTGTTGCTCCGCACTTGCGCGGTGGATTTCTAAGCTGCCTATGCGGCAGTGAAC

>NZ_CP046816|2|2|289657-290705|PILER-CR
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ATCAAAAAAACGAGGTCACGTTCCCAGTTCCC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TACGATGCCGTCCAAGAGGGAATCTTGATGTT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GCCGCGCTTCATGTAACGCATTGACTAATCTA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CGGCGCGAAAAAAGTTTCGAGAGGGCTTAAAC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TTGTTGCTAATCGCATAAGGCGCTTGCATTCC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TCTACTGAGTGAGTGACGACTTCTTCGGTAAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TATTCACTCATGCTGGCTTCGTTGCCCAAGAC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ATCGAGTGGCGAATTTATCGCTATTGCCGAGC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AAGGCATTGCGGAGTATTTGCTTGTTGGTGAG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AAAGCCATAATTAAAACCACCCTTCTTTTTTAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GTGACGTTCAAAATAAACCGGACGTTTTTTAG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TCACCACGGTAATCACTATCAATCACACCAAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AAGCAATATCAACACGAGTAATTTTAACCGAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ATACTAAATATGGTCAAACTATTGCCCTTGCT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GATATGGGTTATCACGCGAGCTTGGCGAATCG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AAAATGGTAGCGGCTCCGCTTCGTTTGCTTTT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CAGAAGTTGTTGCTCCGCACTTGCGCGGTGGA
TTTCTAAGCTGCCTATGCGGCAGTGAAC

>NZ_CP046816|2|1|289657-290705|CRISPRCasFinder
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ATCAAAAAAACGAGGTCACGTTCCCAGTTCCC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TACGATGCCGTCCAAGAGGGAATCTTGATGTT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GCCGCGCTTCATGTAACGCATTGACTAATCTA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CGGCGCGAAAAAAGTTTCGAGAGGGCTTAAAC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TTGTTGCTAATCGCATAAGGCGCTTGCATTCC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TCTACTGAGTGAGTGACGACTTCTTCGGTAAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TATTCACTCATGCTGGCTTCGTTGCCCAAGAC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ATCGAGTGGCGAATTTATCGCTATTGCCGAGC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AAGGCATTGCGGAGTATTTGCTTGTTGGTGAG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AAAGCCATAATTAAAACCACCCTTCTTTTTTAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GTGACGTTCAAAATAAACCGGACGTTTTTTAG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TCACCACGGTAATCACTATCAATCACACCAAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AAGCAATATCAACACGAGTAATTTTAACCGAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ATACTAAATATGGTCAAACTATTGCCCTTGCT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GATATGGGTTATCACGCGAGCTTGGCGAATCG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AAAATGGTAGCGGCTCCGCTTCGTTTGCTTTT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CAGAAGTTGTTGCTCCGCACTTGCGCGGTGGA
TTTCTAAGCTGCCTATGCGGCAGTGAAC

>NZ_CP046816|2|1|289657-290705|CRT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ATCAAAAAAACGAGGTCACGTTCCCAGTTCCC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TACGATGCCGTCCAAGAGGGAATCTTGATGTT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GCCGCGCTTCATGTAACGCATTGACTAATCTA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CGGCGCGAAAAAAGTTTCGAGAGGGCTTAAAC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TTGTTGCTAATCGCATAAGGCGCTTGCATTCC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TCTACTGAGTGAGTGACGACTTCTTCGGTAAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TATTCACTCATGCTGGCTTCGTTGCCCAAGAC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ATCGAGTGGCGAATTTATCGCTATTGCCGAGC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AAGGCATTGCGGAGTATTTGCTTGTTGGTGAG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AAAGCCATAATTAAAACCACCCTTCTTTTTTAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GTGACGTTCAAAATAAACCGGACGTTTTTTAG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TCACCACGGTAATCACTATCAATCACACCAAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AAGCAATATCAACACGAGTAATTTTAACCGAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ATACTAAATATGGTCAAACTATTGCCCTTGCT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GATATGGGTTATCACGCGAGCTTGGCGAATCG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AAAATGGTAGCGGCTCCGCTTCGTTTGCTTTT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CAGAAGTTGTTGCTCCGCACTTGCGCGGTGGA
TTTCTAAGCTGCCTATGCGGCAGTGAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046816.1\|WP_078927563.1\|301089_302229_-\|ISAs1-family-transposase	unknown	unknown	gnl\|CDD\|379382
NZ_CP046816.1\|WP_078927570.1\|292156_292729_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_078927570.1\|279244_279817_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_078927568.1\|282707_283193_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_078927578.1\|287633_288839_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271177
NZ_CP046816.1\|WP_078927571.1\|278540_279248_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379603
NZ_CP046816.1\|WP_115173907.1\|284187_285756_-\|replication-endonuclease	unknown	unknown	gnl\|CDD\|336220
NZ_CP046816.1\|WP_078927569.1\|280114_282265_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_115173905.1\|286311_287283_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_078927575.1\|298588_298825_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378935
NZ_CP046816.1\|WP_078927576.1\|283192_284071_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_115173903.1\|295507_296407_-\|DUF1837-domain-containing-protein	unknown	unknown	gnl\|CDD\|378078
NZ_CP046816.1\|WP_078927564.1\|300248_301109_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271177
NZ_CP046816.1\|WP_115173901.1\|298344_298596_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_078927575.1\|285996_286233_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378935
NZ_CP046816.1\|WP_078927571.1\|291452_292160_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379603
NZ_CP046816.1\|WP_115173902.1\|296800_298348_-\|replication-endonuclease	unknown	unknown	gnl\|CDD\|336220
NZ_CP046816.1\|WP_115173906.1\|285752_286004_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_078927565.1\|298915_299887_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_115173904.1\|293192_295541_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224125

Protein	Function_ID	Function_description	E-value
NZ_CP046816.1\|WP_115173902.1\|296800_298348_-\|replication-endonuclease	gnl\|CDD\|336220	pfam05840, Phage_GPA, Bacteriophage replication gene A protein (GPA). This family consists of a group of bacteriophage replication gene A protein (GPA) like sequences from both viruses and bacteria. The members of this family are likely to be endonucleases.	2.24345e-90
NZ_CP046816.1\|WP_078927571.1\|291452_292160_+\|hypothetical-protein	gnl\|CDD\|379603	pfam14412, AHH, A nuclease family of the HNH/ENDO VII superfamily with conserved AHH. AHH is a predicted nuclease of the HNH/ENDO VII superfamily of the treble clef fold. The name is derived from the conserved motif, AHH. It is found in bacterial polymorphic toxin systems and functions as a toxin module. Like WHH and LHH, the AHH nuclease contains 4 conserved histidines of which, the first one is predicted to bind a metal-ion and the other three ones are involved in activation of a water molecule for hydrolysis.	4.21495e-09
NZ_CP046816.1\|WP_078927575.1\|298588_298825_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	1.2484e-05
NZ_CP046816.1\|WP_078927564.1\|300248_301109_-\|site-specific-integrase	gnl\|CDD\|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	9.77001e-43
NZ_CP046816.1\|WP_078927578.1\|287633_288839_-\|site-specific-integrase	gnl\|CDD\|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.94103e-39
NZ_CP046816.1\|WP_078927571.1\|278540_279248_+\|hypothetical-protein	gnl\|CDD\|379603	pfam14412, AHH, A nuclease family of the HNH/ENDO VII superfamily with conserved AHH. AHH is a predicted nuclease of the HNH/ENDO VII superfamily of the treble clef fold. The name is derived from the conserved motif, AHH. It is found in bacterial polymorphic toxin systems and functions as a toxin module. Like WHH and LHH, the AHH nuclease contains 4 conserved histidines of which, the first one is predicted to bind a metal-ion and the other three ones are involved in activation of a water molecule for hydrolysis.	4.21495e-09
NZ_CP046816.1\|WP_115173907.1\|284187_285756_-\|replication-endonuclease	gnl\|CDD\|336220	pfam05840, Phage_GPA, Bacteriophage replication gene A protein (GPA). This family consists of a group of bacteriophage replication gene A protein (GPA) like sequences from both viruses and bacteria. The members of this family are likely to be endonucleases.	7.64193e-91
NZ_CP046816.1\|WP_078927575.1\|285996_286233_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	1.2484e-05
NZ_CP046816.1\|WP_078927563.1\|301089_302229_-\|ISAs1-family-transposase	gnl\|CDD\|379382	pfam13808, DDE_Tnp_1_assoc, DDE_Tnp_1-associated. This domain is frequently found N-terminal to the transposase, IS family DDE_Tnp_1, pfam01609 and its relatives.	1.7284e-33
NZ_CP046816.1\|WP_115173904.1\|293192_295541_-\|hypothetical-protein	gnl\|CDD\|224125	COG1204, COG1204, Superfamily II helicase [General function prediction only].	7.1705e-12
NZ_CP046816.1\|WP_115173903.1\|295507_296407_-\|DUF1837-domain-containing-protein	gnl\|CDD\|378078	pfam08878, DUF1837, Domain of unknown function (DUF1837). This family of proteins are functionally uncharacterized.	2.16735e-20

>NZ_CP046816.1|WP_078927578.1|287633_288839_-|site-specific-integrase
MAIKQKITATSIKNLTVEQERLNDTEISGFHARISPKGAIKYYFYYRLKGKQRNYLIGSAEALTPAQARDIAKEKAGLVAKGEDVQASRHEAKKREMRKSLTLGRYLEEHYKAYLVAMNPNSARKAYLCIANSFKHLAHKPLDDITAWDIQQWISERRKLGRAPATITYAVNRLRAAFNRAVEWEFIDSHNLAKVKVIHQDNTRIRYLSKEEEKTLLAALSSRDAQLRESQPVRGHQAATAHAGRYVDYLEPLIVMAMNTGLRRGELLTLRWEHISLPNRYLTIRSENAKSKKRRAVPLNDTVFHLLEAWRVQNPNADVVFVHRGQPVSFFSYQWRNLLKEAKIEQFRFHDLRHHFASKLVMAGVDLNTVRELLGHADLKMTLRYAHLAPEHKAAAVNLIG
>NZ_CP046816.1|WP_115173905.1|286311_287283_-|hypothetical-protein
MSQMQRQYLRLEEITEKTRLTQGDVWEAVEQEKLSLCANIAASRLGAYAQDGKTIMAIFDYQGMVQLEASVAKAFALSLEPQTCQRMTILQPEWVNQWQTVSAAFPKVTQAGFAYQNQPISPPLHAFLASGKMTASLTQSSLIGHAGETMNAIFSQLSDTLSDSVAEKQKAFAEKYPAKDEERLSIQAITINPTHLRVAVSDLVAVFGEQVLMMAEHGTSQEKGASVRCHVANQPVLTHPIAQIAYRVLESNPNAKANKIWNLIRSEVNQNGAQRVFDTDAIIDEMTLDHVTWFGRGDADNAMQYNSFRMNILPKVRRALNGQ
>NZ_CP046816.1|WP_078927575.1|285996_286233_-|helix-turn-helix-domain-containing-protein
MTTPIKRAFTEQETAHYIGMSRSFLRQARMEGHRHNRTIAPPFIKIGRAVRYLKDDLDQWLDSHARLDHLSQGGQYHA
>NZ_CP046816.1|WP_115173906.1|285752_286004_-|hypothetical-protein
MLNLTQKQKELLTWMREEKTVEVCSDYCTKNGEAVGKSRLPIRVFRSTINKLYQEGLITYQPKLHYGLRWDVFTLTEKGEALA
>NZ_CP046816.1|WP_115173907.1|284187_285756_-|replication-endonuclease
MKEIDYNLIERDDQAFVRQRLSCFPLSIQWLLFKEYQNQPTKFERNTYLRLTTDQLAEKLSIPLDQLALNLSEDELRQKAKEYAKATLAMRRYYLNDEEALSTVHHFVQSQGVTVCRDGAYSLNGELSRYSDHQWWLRQLRKALRRNIEVVQHHLNQVNKKKSLYCSPLTLQARRQQKAYQQAYLENTFAVNEQGDRFSLLELSQKGVADPKIRKGELMVRARGFEDMANELGHVATFITFTCPSKYHRSYSQSGQVNPKWAGYTPLDGQHYLNALWQLIRSKLNRLGIRFYGFRVAEPQHDGTPHWHLLLFVEPEHYQAMVTIMRDYALKEDGDEQGAQAHRFTEVKIDPSKGSATGYIAKYISKNIDGNHLDSGVYGEDPLEAAARVDAWAACWGIRQFQQLGGCSVTVWRELRRLKTLLGLNERQQSIVEAADKGDWKTFTAQMGGVFSTRKEQVFKPYYELSVETSTGVVKTSQYCENERVKALKGVVSAGREFITRVFQWRLEALVTTIPSTRLCHY
>NZ_CP046816.1|WP_078927576.1|283192_284071_-|hypothetical-protein
MLSVQEKKQLKHMIEANQHEIFIVSMEEMDAIVRSSPKGNLPHIKNSWQQLKGKAEIGVGYYASADDLRTLSKLIGDLGGVTTKAYVKSYGGKPHIILKGNPRLRYFLTGTKYGINNPKVITIGLGKAGAIHAAKSGGILSIVLLSSYRVVDYFLTDNATLTQLVGSLATDVVKIGITTGASIAAASGFVALGFTVAIGPIAAVVFVGVLTSVALSFLDEHYGITQSIIAGLDEISQNVSRRAEKTKGAFYKKIGTFADSVFDYAVDSAKGILINTAKHTMDKFFSAKPRFQ
>NZ_CP046816.1|WP_078927568.1|282707_283193_-|hypothetical-protein
MNDQPQASLLVRLLSLAFFMLLTFGAFSWFSVSSVNLISTLRAESQVIGFDKGAMYTLGCGLGLLVITVGGLMQGILKLKLTEKQHSFFLRSIVVSLLLMVIYPQVAHYTVDNYLKSKRYSICEEVSYQWLIYSKLYYTKDNIACSNLIREKSIASSENEF
>NZ_CP046816.1|WP_078927569.1|280114_282265_-|hypothetical-protein
MRFNLGNSSIINIFVMPDQDDGTMNSPFQGFLVDVFSDDYYQTMTKVLSYPINATEVFMSQQELIEYRCEFGYPNLFLLNIRSLVETLPFFLNHPFVCITCIGDELKFVKTLDLQLKYSPLIIGVEPEVDLDISRFNMFMLDDFIIKRTNEALNNGDLPREFSKYIDNRQPREKQANILKTPTRTHSVTHPNELVLMSVGFDFEYVNTLRGSGDKNVFINAIIDSSRNLQSILNYRRDDSKSDLIVYSPSIFTHLYNFKDHFWNQINRELKNKSAKSFIMNGVFKNPSYSGMDLDKSMIKDMSKVLDNKAFQAIMGTRQFELAYTTLAMNSLAIANMCPAVRVPNAINFHNGMLRDIESLSNIDDKKAKVNFQKKIRNLTNSMKEEIGDKLINFISDSESITLCTDTPLEWVIFNKVPLMFTHEVSKIHTTPGNQLLKISTNFSNFTFKHDELLRITVFRSFRETDPLKHTLEHGLKHFAQIDNKVTIKIVDVENEQELIEALNKVDTPILIFDCHGNHGGSDEHGWLCIGNDRVDVWNLPCNGKIPPIVILSACLTSAIGGSHASVANGLLRHGAITVLGTLLPVDAVKSSVFVGRIIYRLSGYLSALKSLGVDYLTWRKFLSSFFRMSFCTDVLTELRDIYGWLDRKQYEQVHFEANKVINMGRPDWFYVIVDKLTFETGKTRKEVEDAIDEIGFVETMNYSQLGRPENVIIRL
>NZ_CP046816.1|WP_078927570.1|279244_279817_+|hypothetical-protein
MSIYQLKPDFERFKTFELDVVTLAEQLGNVELIDTLMEAPATSESLKTIWNDGVSFDFYGDSAQKNEPDITTWDVSFLVMNKQAYEVVRSELEKVGEFLPIEIGNKPFFVFHCLSFGLEDTGLTEMEYQGGYPIGLKSLAFVEPDIRFKAVFKSKLQGAGKLFATERLKKLCDENRLQGLRFDTDLVDPF
>NZ_CP046816.1|WP_078927571.1|278540_279248_+|hypothetical-protein
MKKVILSKSPIQSIPARPSNPTPLELAINRFQREAVRVRQNLQQEPKPDGMALKKIKEDLAFLDRELIRISTQSSLQSNLSEYRESNKQKKSHELVKEPHHPTKQLASHLYAVAEPQPSKNHQAHHIVMGKGNARMMRTRLQMHLYGIGINDPVNGVWLPRSTAFEGHFTTPKAPPHSRIHSHNYQTWISDSLVNIRKSETQFVNKLRIIKLDIKNGTHPTKILEKKDINWSPSK
>NZ_CP046816.1|WP_078927571.1|291452_292160_+|hypothetical-protein
MKKVILSKSPIQSIPARPSNPTPLELAINRFQREAVRVRQNLQQEPKPDGMALKKIKEDLAFLDRELIRISTQSSLQSNLSEYRESNKQKKSHELVKEPHHPTKQLASHLYAVAEPQPSKNHQAHHIVMGKGNARMMRTRLQMHLYGIGINDPVNGVWLPRSTAFEGHFTTPKAPPHSRIHSHNYQTWISDSLVNIRKSETQFVNKLRIIKLDIKNGTHPTKILEKKDINWSPSK
>NZ_CP046816.1|WP_078927570.1|292156_292729_+|hypothetical-protein
MSIYQLKPDFERFKTFELDVVTLAEQLGNVELIDTLMEAPATSESLKTIWNDGVSFDFYGDSAQKNEPDITTWDVSFLVMNKQAYEVVRSELEKVGEFLPIEIGNKPFFVFHCLSFGLEDTGLTEMEYQGGYPIGLKSLAFVEPDIRFKAVFKSKLQGAGKLFATERLKKLCDENRLQGLRFDTDLVDPF
>NZ_CP046816.1|WP_115173904.1|293192_295541_-|hypothetical-protein
MDRFKEASFIIKSVNEYQLGTMDEPSFIKAICGYFDCIKKQNLTKSDLKFLKYISNMCGIPHYYDLMVGKFGHEDRINDFDLNTLSSSIYESTLYVDDQVKLHKYQKQVINLFNKDCNNRYFLSATTSFGKTFLIYEIIKKLEYKNVALIFPTIALLSENYERLFTNDSYRFFYDEFNIHTLSDVDDLDDDNKNIFIYTPERYLSFVDKYPDIKIDFVFVDEIYKIDNEYLIDTSNNENERDTAYRVALQNILSKTPDILLVGPYIKFPDKTSVTVNQSFNTFLNNNFFQIIDYNNYEIVNKSINVLHGRNNEIDSQLSIDLYGWGKNIGLKISKVYQDILNINENAIVYTRGAGTAEGYVKKSILAHVNNDNDKSDLLVKFINHLKSEFSFSDSWVIIEALENRVGIHHGLVPKYIQKEIINFFNQGDLDLLVSTTTITEGVNTSAKNLIVTNSRKGNKPLKTFDAKNIAGRAGRFLHHFSGRVIVLDKKFKDILDGNDDVIKHKNYDAEVEKDEIDYFITDEAFLSREDIERKRSILMEQQKRAIPDEIMAMYKVISHSHKIVVYDNIIKFSPMHHQTIRKLIKAINSQMFLDFDGFQVVLNSFRPIVTSDKLQRLIDYKAAAKGKNAGRQYSVIVFMLNSYLKSGFHGSVQYIVENKTKQTKKGERPYTIDEAIRESSDFIFSTLKYQLVKYLGVFNLMYKYAISSNNNVDIGEVAGIDRLLLKLEYNATTEKGRLASDYGVPSKLLDYYEDGENESDLKKLDQFELEKFIQIEAIFNK
>NZ_CP046816.1|WP_115173903.1|295507_296407_-|DUF1837-domain-containing-protein
MRRSLQELLKKTIFLKFRLPHSELDLDSIQLSTVEDEVFECTSDNALSEIIYNSIIEYSFNEFDLQDCELDSLLSVALKTKIKYKEYQTQETKIKYGFYGEVLLYLMLCQFYNSSPLISRGYFYNPLENSETKGYDSYHLIEGEEKIELWFGEVKFRTTLDSGAKSAIEGLEKAFSDGYLEDNILAIVNHRNNLGVKGSKLESVIDSWVKNPTINIIDEVKKYNMKLVYPVFLIYPSDCSDLESQIKKTVKYINDKFSKKSYSLSIDYELFFMLMPVGNVKNIKEEVIAWIDSKKPLLS
>NZ_CP046816.1|WP_115173902.1|296800_298348_-|replication-endonuclease
MKEIDYNLLERDDQAFVRQRLSCFPLSIQWLLFKEYQNQPTKFERNTYLRLTTDQLAEKLSIPLDQLALNLSEDELRQKAKEYAKATLAMRRYYLNDEEALSNVHHFVQSHGVTICRDGAYSLNGELSRYSDHQWWLRQLRKALRRNIEVVQHHLNQVNNKKSLYCSPLTLQARRQQKAYQQAYLENTFAVNEQGDRFSLLELSQKGVADPKIRKGELMVRARGFEEMANELGHVATFITFTCPSKYHRSYSQSGQVNPKWAGYTPLDGQHYLNAIWQFIRSKLNRRGIRFYGFRVAEPQHDGTPHWHLLLFVEPEHYQAMVAIMRDYALKEDGDEQGAQAHRFTEVKIDPSKGSATGYIAKYISKNIDGNHLDSGVYGEDPLEAAARVDAWAACWGIRQFQQLGGCSVTVWRELRRLKTLLGLNERQQSIVEAADKGDWKTFTAQMGGVFCTRKEQVFKPYYELSVETSTGVVKTSLYCENERVKALKGVVSAGREFITRVFQWRLEFQVRHAF
>NZ_CP046816.1|WP_115173901.1|298344_298596_-|hypothetical-protein
MLNLTQKQKELLTWMREEKTVEVCSDYCTKNGEVAGKSRLPIRVHRPTINKLYQEGLITYQAKLHYGLRWDVFTLTEKGEALA
>NZ_CP046816.1|WP_078927575.1|298588_298825_-|helix-turn-helix-domain-containing-protein
MTTPIKRAFTEQETAHYIGMSRSFLRQARMEGHRHNRTIAPPFIKIGRAVRYLKDDLDQWLDSHARLDHLSQGGQYHA
>NZ_CP046816.1|WP_078927565.1|298915_299887_-|hypothetical-protein
MSQMQRQYLRLEDITEKTRLTQGDVWEAVEQETLPLCASIAASRLGAYAQDGKTIMAIFDYQGMVQLEASVAKAFALSLEPKTCQRMTILQPEWVNQWQTVSAAFPKVTQAGFAYQNQPISPPLHAFLASGKMIASLTQSSLIGQAGETMNAIFSQLSGTLSDSVAEKQKAFAEKYPAKDEERLSIQAITITPTHLRVAVSDLVAVFGEQVLMMAEHGTSQAKGASVRFHVANQPVLTHPIAQIAYRVLESNPKAKANKIWNLIRREVNQSGAQRVFDTDAIIDEMTLDHVTWFGRSDADNTMQYDSFRMNILPKVRRALNGQ
>NZ_CP046816.1|WP_078927564.1|300248_301109_-|site-specific-integrase
MYGNVHDFSVPNSARKAYLCIANSFKHLAHKPLDDITAWDIQQWISERRKLGRAPATITYAVNRLRAAFNRAVEWEFIDSHTLGKVKVIHQDNTRVRYLSKEEEKALLAALTSRDARLRESLASTAQAGRYVDYLEPLIVMAMHTGLRRGELLTLRWEHISLPNRYLTIRSENAKSKKRRTVPLNDTVFHLLDAWRAQNPSADFVFVHRGQPVSFFSYQWRNLLKEAKIEQFRFHDLRHHFASKLVMAGVDLNTVRELLGHADLKMTLRYAHLAPEHKAAAVNLIG
>NZ_CP046816.1|WP_078927563.1|301089_302229_-|ISAs1-family-transposase
MSNQHPFMHFDVIPDYRQQGKVEHKLTDIILLTICAVLSGQDDWKAIHLYGTRWLDFLKRFGDFSHGVPSTITIARVMGMINATRLQKCFIEWMKSCCELTDGEVIAIDGKTVRGSYDDSRGLGAIHMVNAFATENGVCLGQHKVYEKSNEITAIPELLQLLDISGCLVTIDAMGCQKKIAQKILEKNADYLLAVKGNQGRLEEAFDNYFDMSMLQKHDGDSYSTQEKSRGRQETRLALVNEDLRVLGDLELDWPGLKTMGIVVSIRQESAVAQESEVTVRYYISSKALSAKELLNASRSHWLVESMHWMLDTEFGEDACRKRAEERAENFARIRQMCLNMLKSETTLKASIKHKRAMCAMDPEYLLKALGSLYLRECS

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Crispr_ID: NZ_CP046816_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046816_3

316704-317198

Orphan

I-F

Consensus_repeat	Method
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CRISPRCasFinder
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CRT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	PILER-CR

8 spacers

The CRISPR arrays of NZ_CP046816_3

>merge|NZ_CP046816|3|316704-317198|CRISPRCasFinder,CRT,PILER-CR
TTTCTAAGCTGCCTATGCGGCAGTGAACCTGCTATGTTTAAATCAATTTCTAAGCTGCCTATGCGGCAGTGAACAGGGATAATATTATTTCCTGTTATTTTCTCTTTTTCTAAGCTGCCTATGCGGCAGTGAACTGCTTGATTGCCCCAGTTCACGCCCTCTACAGTTTCTAAGCTGCCTATGCGGCAGTGAACGTTGCGTGTGATATTTTAGCTGCCTCATTTTGTTTCTAAGCTGCCTATGCGGCAGTGAACAGTTGAAAGGTATCCCGTAAATCTTGCCATTATTTCTAAGCTGCCTATGCGGCAGTGAACTTGGGCCTACTAATCGCTGGGGGATGCTTGACTTTCTAAGCTGCCTATGCGGCAGTGAACAATTTCAACGATGTCACGCTGTGACTCCATGATTTTCTAAGCTGCCTATGCGGCAGTGAACTCAGGGAGCAAACGCGCAACTGCAATTCATTGTTTCTAAGCTGCCTATGCGGCAGTGAAC

>NZ_CP046816|3|2|316704-317198|CRISPRCasFinder
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CTGCTATGTTTAAATCAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AGGGATAATATTATTTCCTGTTATTTTCTCTT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TGCTTGATTGCCCCAGTTCACGCCCTCTACAG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GTTGCGTGTGATATTTTAGCTGCCTCATTTTG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AGTTGAAAGGTATCCCGTAAATCTTGCCATTA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TTGGGCCTACTAATCGCTGGGGGATGCTTGAC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AATTTCAACGATGTCACGCTGTGACTCCATGAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TCAGGGAGCAAACGCGCAACTGCAATTCATTG
TTTCTAAGCTGCCTATGCGGCAGTGAAC

>NZ_CP046816|3|2|316704-317198|CRT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CTGCTATGTTTAAATCAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AGGGATAATATTATTTCCTGTTATTTTCTCTT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TGCTTGATTGCCCCAGTTCACGCCCTCTACAG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GTTGCGTGTGATATTTTAGCTGCCTCATTTTG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AGTTGAAAGGTATCCCGTAAATCTTGCCATTA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TTGGGCCTACTAATCGCTGGGGGATGCTTGAC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AATTTCAACGATGTCACGCTGTGACTCCATGAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TCAGGGAGCAAACGCGCAACTGCAATTCATTG
TTTCTAAGCTGCCTATGCGGCAGTGAAC

>NZ_CP046816|3|3|316750-317198|PILER-CR
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AGGGATAATATTATTTCCTGTTATTTTCTCTT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TGCTTGATTGCCCCAGTTCACGCCCTCTACAG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GTTGCGTGTGATATTTTAGCTGCCTCATTTTG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AGTTGAAAGGTATCCCGTAAATCTTGCCATTA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TTGGGCCTACTAATCGCTGGGGGATGCTTGAC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AATTTCAACGATGTCACGCTGTGACTCCATGAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TCAGGGAGCAAACGCGCAACTGCAATTCATTG
TTTCTAAGCTGCCTATGCGGCAGTGAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046816.1\|WP_115173899.1\|310310_311144_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_072668974.1\|317355_317466_-\|DUF3265-domain-containing-protein	unknown	unknown	gnl\|CDD\|288509
NZ_CP046816.1\|WP_115173898.1\|314539_314953_-\|GFA-family-protein	unknown	unknown	gnl\|CDD\|226314
NZ_CP046816.1\|WP_115173894.1\|315619_316033_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224011
NZ_CP046816.1\|WP_139364804.1\|317911_318007_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|293766
NZ_CP046816.1\|WP_004394087.1\|309434_309707_+\|DUF1778-domain-containing-protein	unknown	unknown	gnl\|CDD\|226860
NZ_CP046816.1\|WP_113594551.1\|322132_322249_-\|DUF3265-domain-containing-protein	unknown	unknown	gnl\|CDD\|288509
NZ_CP046816.1\|WP_115173897.1\|315459_315582_-\|DUF3265-domain-containing-protein	unknown	unknown	gnl\|CDD\|288509
NZ_CP046816.1\|WP_115173900.1\|310221_310362_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_158142139.1\|322548_322704_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_078927600.1\|309703_310201_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
NZ_CP046816.1\|WP_078927598.1\|312160_313135_-\|FRG-domain-containing-protein	unknown	unknown	gnl\|CDD\|214898
NZ_CP046816.1\|WP_115173896.1\|323285_323492_-\|transposase	unknown	unknown	gnl\|CDD\|366690
NZ_CP046816.1\|WP_158116599.1\|313183_314035_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP046816.1\|WP_078927646.1\|318429_318729_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_158116599.1\|319395_320247_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP046816.1\|WP_113594550.1\|322245_322548_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_025590728.1\|322864_323284_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_078927644.1\|317462_317897_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP046816.1\|WP_078927599.1\|311143_311989_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|340998

Protein	Function_ID	Function_description	E-value
NZ_CP046816.1\|WP_072668974.1\|317355_317466_-\|DUF3265-domain-containing-protein	gnl\|CDD\|288509	pfam11665, DUF3265, Protein of unknown function (DUF3265). This family of proteins with unknown function appear to be restricted to Vibrio.	0.000269016
NZ_CP046816.1\|WP_115173898.1\|314539_314953_-\|GFA-family-protein	gnl\|CDD\|226314	COG3791, COG3791, Uncharacterized conserved protein [Function unknown].	4.96957e-26
NZ_CP046816.1\|WP_115173894.1\|315619_316033_-\|hypothetical-protein	gnl\|CDD\|224011	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	0.000996416
NZ_CP046816.1\|WP_139364804.1\|317911_318007_-\|hypothetical-protein	gnl\|CDD\|293766	cd16147, G6S, glucosamine (N-acetyl)-6-sulfatase(G6S, GNS) AND sulfatase 1(SULF1). N-acetylglucosamine-6-sulfatase also known as glucosamine (N-acetyl)-6-sulfatase hydrolyzes of the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate. Deficient of N-acetylglucosamine-6-sulfatase results in disease of Sanfilippo Syndrome type IIId or Mucopolysaccharidosis III (MPS-III), a rare autosomal recessive lysosomal storage disease. SULF1 encodes an extracellular heparan sulfate endosulfatase, that removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs).	0.00458478
NZ_CP046816.1\|WP_004394087.1\|309434_309707_+\|DUF1778-domain-containing-protein	gnl\|CDD\|226860	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown].	3.76486e-19
NZ_CP046816.1\|WP_113594551.1\|322132_322249_-\|DUF3265-domain-containing-protein	gnl\|CDD\|288509	pfam11665, DUF3265, Protein of unknown function (DUF3265). This family of proteins with unknown function appear to be restricted to Vibrio.	3.98105e-05
NZ_CP046816.1\|WP_115173897.1\|315459_315582_-\|DUF3265-domain-containing-protein	gnl\|CDD\|288509	pfam11665, DUF3265, Protein of unknown function (DUF3265). This family of proteins with unknown function appear to be restricted to Vibrio.	5.71977e-06
NZ_CP046816.1\|WP_078927600.1\|309703_310201_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	3.07883e-06
NZ_CP046816.1\|WP_078927598.1\|312160_313135_-\|FRG-domain-containing-protein	gnl\|CDD\|214898	smart00901, FRG, This domain contains a conserved N-terminal (F/Y)RG motif. It is functionally uncharacterised.	5.8248e-14
NZ_CP046816.1\|WP_115173896.1\|323285_323492_-\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	2.35e-08
NZ_CP046816.1\|WP_158116599.1\|313183_314035_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.33291e-69
NZ_CP046816.1\|WP_158116599.1\|319395_320247_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.33291e-69
NZ_CP046816.1\|WP_078927644.1\|317462_317897_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.42776e-09
NZ_CP046816.1\|WP_078927599.1\|311143_311989_-\|hypothetical-protein	gnl\|CDD\|340998	cd17440, MFS_SV2C, Synaptic vesicle glycoprotein 2C of the Major Facilitator Superfamily of transporters. Synaptic vesicle glycoprotein 2 (SV2) is a transporter-like integral membrane glycoprotein, with 12 transmembrane regions, expressed in vertebrates and is localized to synaptic and endocrine secretory vesicles. Three isoforms have been identified, SV2A, SV2B, and SV2C. SV2A and SV2B are widely expressed in the brain, while SV2C is more restricted to evolutionarily older brain. SV2 isoforms have been shown to be critical for the proper function of the central nervous system. SV2 serves as the receptor for botulinum neurotoxin A (BoNT/A), one of seven neurotoxins produced by the bacterium Clostridium botulinum. BoNT/A blocks neurotransmitter release by cleaving synaptosome-associated protein of 25 kD (SNAP-25) within presynaptic nerve terminals. SV2C exhibits enriched expression in several basal ganglia nuclei, and has been found to be involved in normal operation of the basal ganglia network and could be also be involved in system adaptation in basal ganglia pathological conditions. SV2C belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.82398e-05

>NZ_CP046816.1|WP_115173894.1|315619_316033_-|hypothetical-protein
MGLVIAPVVVFWIVSFFFSWRMGYYLLMDKPFFPYILTIIFVALLSALTYVLFGLFTFKGRSEIWVFEIPWFFLLNKYAIVSFLLSLMAYLFGSNFFNSDISKAAIFIIAFSITLGSLIGCFSSSAFMQKYNISVMY
>NZ_CP046816.1|WP_115173897.1|315459_315582_-|DUF3265-domain-containing-protein
MAFLVCGDFCGESGLRKAGLCGTHPLTRRYVTIEKKIAIY
>NZ_CP046816.1|WP_115173898.1|314539_314953_-|GFA-family-protein
MKGHAKCLCGSVALEVEYASNEVAACHCSICRNWGGGPMLAIDCADSVKISGEESVTRYSSSEWADRGFCNKCGTHLFYYLKPANQYHLPVGLLQGDDNFQFTHQIFVDEKPEYYDFKNETQNMTGAEVFAHFEAEG
>NZ_CP046816.1|WP_158116599.1|313183_314035_-|IS3-family-transposase
MKYEYIESYVGEYKVTHMCRALDVSPSGYYKWLNREPSERSKRRCRFEQLVMCTFAKHRARYGSVRIAEALNESGYTCCVNYIADIMKEKGIKARNGIGFKYTKDVAAMTNVADNLLRRDFEAKRPNQKWVTDITYIWVKSRWLYLATVLDLHSRRIVGWSLDTTMTVQLITNALKMAFKSRKPAKGVIIHSDRGVQYRAHDYQDFMRKHGGVPSMSRKGNCWDNAVMESFYSRLKVELIYAEDYQTIEEARMGIFEYIEIYYNRNRKHSALGYVSPVEFESV
>NZ_CP046816.1|WP_078927598.1|312160_313135_-|FRG-domain-containing-protein
MKKFRSLSDLINYLKDNDIKNSLFPQIVDGPSFEWIDKGNGGSAIIPSLNKMSSVYVYRGQSKRFSPCVSSLLRGVVRHEDIFAYKIKLAEFKSILDNPRQQLAKEIGLELNLEALAQHYGLKTTHLDVTHSLSVAAFFACCECTDNVWTPVEKGVGVMYRLPFIPGYTCDLVGAQVYPRPKEQMAQSVLVDVNQDFEKMPFVEIYEFEHSYDESEKYFRMFNEGKDLFPFDLLAEKANLVVNDSSLSIETVLRVMEEDDLADEIREDKLNEVKTKLANSGKYSISHRKEYVFSQSELEILANTLDEVKESLLADTGFRFVFAK
>NZ_CP046816.1|WP_078927599.1|311143_311989_-|hypothetical-protein
MNNFFKLNDGYVEILNADDFKSRLHTSKHLCNLAFMPDEMENEKIESITFEEFSFSKTHLKNIMFKNCIFKNCLFIGSNFEDCSIHGCEFIDCNFFRCKIKNTYAKPQQFRRAITKREYANVAVSLFNELRNQYKEDSQREFKSEAEYYFHKWKRIESVNAAKKDNQKWIKYTPRRVFSYLHYTLFGFGYRLRNLTLTTVVALFIMILVNYQYSSLIFVESPKNMSLIKSTYFTITTMATLGASGFSEFTEFGYIVVIANVLVGISLLTFTANSILKRVVR
>NZ_CP046816.1|WP_115173899.1|310310_311144_-|hypothetical-protein
MLVAEFGSRHNGYASCYSDRDLLIVSSDWSRINFAKNYYSNIGFSVTSFHTSKAKYLAKNGSLFFKHVIDESVLISDSSGIYRELNDSWEPQSNYNREIESNIDLLEMINYMPKSKYTANYVVDMLVISVRNILIRLIAETGRYIFDWETLARVAFEYGYISYSDIALISYSRKVKNRYRMGVYDNVSHHVINGLISILNSVQNESFKLRFLSNKSILSLPERFDNGSYKQLKALEAICCLYSFDPSLMPYMELVKDPNYACATSALTNASRGTVNA
>NZ_CP046816.1|WP_115173900.1|310221_310362_-|hypothetical-protein
MCYKRLNKRFKRDCQRVAFPVLISRSGYGCCALVWCKCVASPLSGR
>NZ_CP046816.1|WP_078927600.1|309703_310201_+|GNAT-family-N-acetyltransferase
MMKTVLLDKDKHDRNRFNCGIDALNNYLKVMASQQAKKDNTRTFVLEDENNTSLIIGFYTLTMTPIDLKALPDKLQKKHQSSTSGGLIARLAIDERYKGKGFGEWLLIDALRKLLAASDSVAFPVVIVDAKDGAKLFYERYGFKSFQDAENKLFITISDIRASLG
>NZ_CP046816.1|WP_004394087.1|309434_309707_+|DUF1778-domain-containing-protein
MATTLPRITARVDVDTQNLLTKAAALAGMSSINSFVLNAAIEKAKQVIEREQTLKLSQADAILLMEALDKPTTLNQKLKTAAERYETKNQ
>NZ_CP046816.1|WP_072668974.1|317355_317466_-|DUF3265-domain-containing-protein
MTNASRGTANAWHFYYALVFVITVLCGELVVALSAP
>NZ_CP046816.1|WP_078927644.1|317462_317897_-|GNAT-family-N-acetyltransferase
MEVKLKSGSDSLFAESLTKTNMAIYYQTRGIIWDHNQFVSSWTQLDNYEVHLEQTRVGIVRFSYSGDATFLRDFQILPEFQGIGIGSKCLDLVVRYALDRQSIRLVLRVFSENPAINLYESKGFVRTSEVNGLVEMEFPLNSNT
>NZ_CP046816.1|WP_139364804.1|317911_318007_-|hypothetical-protein
MAFLLCVGFCDYGVMRKVSSSVCCPLSGRYV
>NZ_CP046816.1|WP_078927646.1|318429_318729_-|hypothetical-protein
MLAEAGKLVWSAGSTIVGVFVEKSKAEELYRFIVPDIQQDLRNGKSFESEKVVSGIKILEKLPPIGARRRNFSRRYLKSKTDFLALPQDPDALSIAYWW
>NZ_CP046816.1|WP_158116599.1|319395_320247_-|IS3-family-transposase
MKYEYIESYVGEYKVTHMCRALDVSPSGYYKWLNREPSERSKRRCRFEQLVMCTFAKHRARYGSVRIAEALNESGYTCCVNYIADIMKEKGIKARNGIGFKYTKDVAAMTNVADNLLRRDFEAKRPNQKWVTDITYIWVKSRWLYLATVLDLHSRRIVGWSLDTTMTVQLITNALKMAFKSRKPAKGVIIHSDRGVQYRAHDYQDFMRKHGGVPSMSRKGNCWDNAVMESFYSRLKVELIYAEDYQTIEEARMGIFEYIEIYYNRNRKHSALGYVSPVEFESV
>NZ_CP046816.1|WP_113594551.1|322132_322249_-|DUF3265-domain-containing-protein
MGITNGSRGTTNAWHFYYALVFVVTVLCGKLVVALVAP
>NZ_CP046816.1|WP_113594550.1|322245_322548_-|hypothetical-protein
MKNLKEFLRASSEASHSQELAFKNASTEIAASALSIGLVSAESKADKFAEEVTKLASSDEVISKLSNDVGVPFPNESEDEFVSRAKKSFKKILMTKLAGK
>NZ_CP046816.1|WP_158142139.1|322548_322704_-|hypothetical-protein
MINKILGFFSWLLSFWKGLSDEDKEKIVDIVVHSMTQIFKTYYRSSKKSEG
>NZ_CP046816.1|WP_025590728.1|322864_323284_-|hypothetical-protein
MERFAYLDTWDKLTPEVFKAVFHYAVNIAKDNNKELTLVVNNVAQCSDFISKFLDQTATNKLAKGTTLQFQGVAVNLKSPFSIKSYQSYGVFCAFHPSDKALDSMESSTSPVAIVILGEQEEHFTSWLREKGGKLLAQG
>NZ_CP046816.1|WP_115173896.1|323285_323492_-|transposase
MAKHRNPAYTEEFRKEAVRLASLPGRTAVSVARELGISAQQIRNWKRQFTRLSDKQFNTLAGRYTKRR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP046816_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046816_4

371755-372443

Orphan

I-F

Consensus_repeat	Method
TTTCTAAGCTGCCTATGCGGCAGTGAAC	PILER-CR
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CRISPRCasFinder
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CRT

11 spacers

The CRISPR arrays of NZ_CP046816_4

>merge|NZ_CP046816|4|371755-372443|PILER-CR,CRISPRCasFinder,CRT
TTTCTAAACTGCCTATGCGGCAGTGAACTTTCTGGGACATTTGAAGCTGAAAAGATGATCTTTCTAAGCTGCCTATGCGGCAGTGAACACAAACGCGGTACGCTTATTTCCATCATTAAATTTCTAAGCTGCCTATGCGGCAGTGAACTAAAATGGTTTTATTGTGCTCTTCGGCAACTTTTTCTAAGCTGCCTATGCGGCAGTGAACATAATTGTCTCTTGAGTTCTGTCGCTCAGTCGTTTCTAAGCTGCCTATGCGGCAGTGAACGTTCTCGTGGTTTTGCTCCTAAAGTGCGTAATTTTCTAAGCTGCCTATGCGGCAGTGAACCCTTTTTGGCTCACTCAGTGGTACTGCCAAATTTTCTAAGCTGCCTATGCGGCAGTGAACTCAAGTTTCGAATTGTAATCCGCACGCCGGAATTTCTAAGCTGCCTATGCGGCAGTGAACTTGACCCAGTGACTCAAACGACCACCCTTTTTTTTCTAAGCTGCCTATGCGGCAGTGAACCTTTCTCCAACTCAAGCTCTGGTTCTGGTTTATTTCTAAGCTGCCTATGCGGCAGTGAACGTGCGCGCAATTAATGCAATCACGGCAGCGATTTTCTAAGCTGCCTATGCGGCAGTGAACAGACGGGCTAAAATCAAATCCATTTGTTGAAATTTTCTAAGCTGCCTATGCGGCAGTGAAC

>NZ_CP046816|4|4|371755-372443|PILER-CR
TTTCTAAACTGCCTATGCGGCAGTGAAC	TTTCTGGGACATTTGAAGCTGAAAAGATGATC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ACAAACGCGGTACGCTTATTTCCATCATTAAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TAAAATGGTTTTATTGTGCTCTTCGGCAACTT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ATAATTGTCTCTTGAGTTCTGTCGCTCAGTCG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GTTCTCGTGGTTTTGCTCCTAAAGTGCGTAAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CCTTTTTGGCTCACTCAGTGGTACTGCCAAAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TCAAGTTTCGAATTGTAATCCGCACGCCGGAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TTGACCCAGTGACTCAAACGACCACCCTTTTT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CTTTCTCCAACTCAAGCTCTGGTTCTGGTTTA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GTGCGCGCAATTAATGCAATCACGGCAGCGAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AGACGGGCTAAAATCAAATCCATTTGTTGAAAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC

>NZ_CP046816|4|3|371755-372443|CRISPRCasFinder
TTTCTAAACTGCCTATGCGGCAGTGAAC	TTTCTGGGACATTTGAAGCTGAAAAGATGATC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ACAAACGCGGTACGCTTATTTCCATCATTAAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TAAAATGGTTTTATTGTGCTCTTCGGCAACTT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ATAATTGTCTCTTGAGTTCTGTCGCTCAGTCG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GTTCTCGTGGTTTTGCTCCTAAAGTGCGTAAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CCTTTTTGGCTCACTCAGTGGTACTGCCAAAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TCAAGTTTCGAATTGTAATCCGCACGCCGGAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TTGACCCAGTGACTCAAACGACCACCCTTTTT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CTTTCTCCAACTCAAGCTCTGGTTCTGGTTTA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GTGCGCGCAATTAATGCAATCACGGCAGCGAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AGACGGGCTAAAATCAAATCCATTTGTTGAAAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC

>NZ_CP046816|4|3|371755-372443|CRT
TTTCTAAACTGCCTATGCGGCAGTGAAC	TTTCTGGGACATTTGAAGCTGAAAAGATGATC
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ACAAACGCGGTACGCTTATTTCCATCATTAAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TAAAATGGTTTTATTGTGCTCTTCGGCAACTT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	ATAATTGTCTCTTGAGTTCTGTCGCTCAGTCG
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GTTCTCGTGGTTTTGCTCCTAAAGTGCGTAAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CCTTTTTGGCTCACTCAGTGGTACTGCCAAAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TCAAGTTTCGAATTGTAATCCGCACGCCGGAA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	TTGACCCAGTGACTCAAACGACCACCCTTTTT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	CTTTCTCCAACTCAAGCTCTGGTTCTGGTTTA
TTTCTAAGCTGCCTATGCGGCAGTGAAC	GTGCGCGCAATTAATGCAATCACGGCAGCGAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC	AGACGGGCTAAAATCAAATCCATTTGTTGAAAT
TTTCTAAGCTGCCTATGCGGCAGTGAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046816.1\|WP_078927628.1\|379786_380899_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368573
NZ_CP046816.1\|WP_078927626.1\|377908_378283_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_078927662.1\|360705_361839_-\|ISAs1-family-transposase	unknown	unknown	gnl\|CDD\|379382
NZ_CP046816.1\|WP_158116599.1\|367637_368489_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP046816.1\|WP_078927669.1\|369472_370072_-\|pentapeptide-repeat-containing-protein	unknown	unknown	gnl\|CDD\|224276
NZ_CP046816.1\|WP_078927637.1\|365149_365857_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274058
NZ_CP046816.1\|WP_078927627.1\|378440_379643_-\|DUF3644-domain-containing-protein	unknown	unknown	gnl\|CDD\|376163
NZ_CP046816.1\|WP_158116599.1\|376037_376889_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP046816.1\|WP_002033296.1\|364745_365015_+\|type-II-toxin-antitoxin-system-YafQ-family-toxin	unknown	unknown	gnl\|CDD\|225583
NZ_CP046816.1\|WP_032480862.1\|364474_364753_+\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	unknown	unknown	gnl\|CDD\|367879
NZ_CP046816.1\|WP_115173886.1\|377735_377912_-\|DUF3265-domain-containing-protein	unknown	unknown	gnl\|CDD\|288509
NZ_CP046816.1\|WP_115173889.1\|372589_372679_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_078927636.1\|366042_366600_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_115173888.1\|373549_374578_-\|IS630-family-transposase	unknown	unknown	gnl\|CDD\|315923
NZ_CP046816.1\|WP_139364809.1\|359896_360664_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_115173883.1\|362073_363399_-\|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NZ_CP046816.1\|WP_078927655.1\|372883_373306_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376074
NZ_CP046816.1\|WP_078927661.1\|374627_375011_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046816.1\|WP_078927660.1\|375157_375988_-\|DUF4238-domain-containing-protein	unknown	unknown	gnl\|CDD\|379425
NZ_CP046816.1\|WP_139364803.1\|366723_366912_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP046816.1\|WP_078927628.1\|379786_380899_-\|hypothetical-protein	gnl\|CDD\|368573	pfam05708, Peptidase_C92, Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family. Amidase_YiiX is a family of permuted papain-like amidases. It has amidase specificity for the amide bond between a lipid and an amino acid (or peptide). From the structure, a tetramer, each monomer is made up of a layered alpha-beta fold with a central, 6-stranded, antiparallel beta-sheet that is protected by helices on either side. The catalytic Cys154 in UniProtKB:Q74NK7, Structure 3kw0, is located on the N-terminus of helix alphaF. The two additional helices located above Cys154 contribute to the formation of the active site, where the lysine ligand is bound.	9.24466e-12
NZ_CP046816.1\|WP_078927662.1\|360705_361839_-\|ISAs1-family-transposase	gnl\|CDD\|379382	pfam13808, DDE_Tnp_1_assoc, DDE_Tnp_1-associated. This domain is frequently found N-terminal to the transposase, IS family DDE_Tnp_1, pfam01609 and its relatives.	1.05113e-34
NZ_CP046816.1\|WP_158116599.1\|367637_368489_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.33291e-69
NZ_CP046816.1\|WP_078927669.1\|369472_370072_-\|pentapeptide-repeat-containing-protein	gnl\|CDD\|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	2.69669e-13
NZ_CP046816.1\|WP_078927637.1\|365149_365857_-\|hypothetical-protein	gnl\|CDD\|274058	TIGR02258, UPF0097_protein_AF_2157, 2'-5' RNA ligase. This protein family consists of bacterial and archaeal proteins with two tandem copies of Pfam domain pfam02834. Members for which activity has been measured perform a reversible, ATP-independent 2'-5'-ligation of what is presumably a non-phyiological substrate: half-tRNA splice intermediates from an intron-containing yeast tRNA. The physiological substrate(s) in prokaryotes may include small 2'-5'-link-containing oligonucleotides, perhaps with regulatory or biosynthetic roles. [Transcription, RNA processing].	0.00825538
NZ_CP046816.1\|WP_078927627.1\|378440_379643_-\|DUF3644-domain-containing-protein	gnl\|CDD\|376163	pfam18740, EC042_2821, EC042_2821-lke REase. REase Fold Fused to HEPN (EC042_2821) and an N-terminal wHTH in some.	4.69461e-22
NZ_CP046816.1\|WP_158116599.1\|376037_376889_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.33291e-69
NZ_CP046816.1\|WP_115173886.1\|377735_377912_-\|DUF3265-domain-containing-protein	gnl\|CDD\|288509	pfam11665, DUF3265, Protein of unknown function (DUF3265). This family of proteins with unknown function appear to be restricted to Vibrio.	0.000665331
NZ_CP046816.1\|WP_032480862.1\|364474_364753_+\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	gnl\|CDD\|367879	pfam04221, RelB, RelB antitoxin. RelE and RelB form a toxin-antitoxin system. RelE represses translation, probably through binding ribosomes. RelB stably binds RelE, presumably deactivating it.	1.04059e-30
NZ_CP046816.1\|WP_115173888.1\|373549_374578_-\|IS630-family-transposase	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	5.68367e-38
NZ_CP046816.1\|WP_002033296.1\|364745_365015_+\|type-II-toxin-antitoxin-system-YafQ-family-toxin	gnl\|CDD\|225583	COG3041, COG3041, Uncharacterized protein conserved in bacteria [Function unknown].	7.0156e-39
NZ_CP046816.1\|WP_115173883.1\|362073_363399_-\|group-II-intron-reverse-transcriptase/maturase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	5.15716e-167
NZ_CP046816.1\|WP_078927655.1\|372883_373306_-\|hypothetical-protein	gnl\|CDD\|376074	pfam18648, ADPRTs_Tse2, Tse2 ADP-ribosyltransferase toxins. Tse2 from P. aeruginosa has structural features similar to ADP-ribosylating toxins. It is a cytoactive toxin secreted by a type six secretion apparatus of Pseudomonas aeruginosa and found mostly in gamma proteobacteria. It naturally attacks a target in the cytoplasm of bacterial cells. Structural analysis shows similarity between Tse2 and nicotinamide adenine dinucleotide (NAD)-dependent enzymes from bacteria, notably the mono-ADP-ribosyltransferase toxins (ADPRTs). Furthermore, it revealed that the Tse2 active site is occluded upon binding the cognate immunity protein Tsi2. The abrogation of toxicity for the R14A, S80A, and H122A mutant Tse2 proteins indicates the importance of these amino acids in the mechanism of Tse2 toxicity and, given their conservation with NAD-reactive enzymes, also supports their assignment as being involved in a catalytic reaction.	2.97559e-06
NZ_CP046816.1\|WP_078927660.1\|375157_375988_-\|DUF4238-domain-containing-protein	gnl\|CDD\|379425	pfam14022, DUF4238, Protein of unknown function (DUF4238). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 274 and 374 amino acids in length.	2.8356e-18

>NZ_CP046816.1|WP_078927669.1|369472_370072_-|pentapeptide-repeat-containing-protein
MTDLKNNEHYFDVSFEKLSSLDGQYSGIEFEDCQFSDCDFSAVKFRKCKFTNCIFERCNLSLVDFSNSKLFELKFQDSKLVGVDWTKAMWAVYHSDFELSFKRCILNDSSFFGLTLNELVFDECKLHDVDFREGNFRGSTMTYSDFSHSLFMRTNLQGVDFSESIAYAIDVLENNVQKAKFSRYEALNLLESLGIELVD
>NZ_CP046816.1|WP_158116599.1|367637_368489_-|IS3-family-transposase
MKYEYIESYVGEYKVTHMCRALDVSPSGYYKWLNREPSERSKRRCRFEQLVMCTFAKHRARYGSVRIAEALNESGYTCCVNYIADIMKEKGIKARNGIGFKYTKDVAAMTNVADNLLRRDFEAKRPNQKWVTDITYIWVKSRWLYLATVLDLHSRRIVGWSLDTTMTVQLITNALKMAFKSRKPAKGVIIHSDRGVQYRAHDYQDFMRKHGGVPSMSRKGNCWDNAVMESFYSRLKVELIYAEDYQTIEEARMGIFEYIEIYYNRNRKHSALGYVSPVEFESV
>NZ_CP046816.1|WP_139364803.1|366723_366912_+|hypothetical-protein
MQHLPNYSKYYQRTALANILKLTRKVSIDPIEKRWQQRKPFDSADHDYRQAEHKPILPLSAE
>NZ_CP046816.1|WP_078927636.1|366042_366600_+|hypothetical-protein
MIKIIMVITTTVTLLIYAIYIAFTGSGYAALGLMFTAILLVWTALIGIESLWESSFSHCLKLAILTCSIANAYYTNNLSKPGYVEKNLDLFYESINIKYCSSQDQPNEEMRVLFNKNKNKLLSKCALQSHLDLQKLNIDLAKARYLDPATGAIDTIYSSLTEPDSLSCQEFAETLNRLCPNKLRL
>NZ_CP046816.1|WP_078927637.1|365149_365857_-|hypothetical-protein
MIQSIYDQMWQRFEQATVQNDYELDAHLLDTTSDTRRGITALAYLKQGNSAVLNEIIKFQQAVREIEPNQYYHPLDELHLTVLSVISCVPKFDLNEINIQAYADIFISVLKTTQLIEIKYHGVSASPNCIVLQGFPTSNALEQFRNNLRTQLSDAGLRVTFDSRYKLVTAHSSLIRFKLPISDGQQLLALCQQYRNYDFGSFVLKDFELVFNNWYQNLVVTKCLAKGSVADQPRV
>NZ_CP046816.1|WP_002033296.1|364745_365015_+|type-II-toxin-antitoxin-system-YafQ-family-toxin
MYSLEYSTQFKKDFKKITKMPISDIIEVGNIISKLQRGEKLDPKNVDHPLTGGWVGFRDCHVKPDLVLIYRIFDDQLQLARIGSHSDLF
>NZ_CP046816.1|WP_032480862.1|364474_364753_+|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin
MRTEMLSTRIDHDTKVAFTSICDEMGLSTSQAIKIFAKAVINHGGIPFDLRVPQPNETTISAMNELVQGHGHKAESVDAMLTELTEGKVKNV
>NZ_CP046816.1|WP_115173883.1|362073_363399_-|group-II-intron-reverse-transcriptase/maturase
MNTERRGNVKPSPSQFNCDKQEETSLEETKPFQINKWQVAEAYKLVKANRGSAGVDNQSLQDFEQNLKGNLYKIWNRLSSGSYVPPPVKGVAIPKKSGGERLLGIPTVSDRVAQMTVLLSFEHKVERHFLDDSYGYRPKKSALDAIAVTRKRCWRYDWCLEFDIKGLFDNIPHELLLKAVDKHVTEKWVRLYIRRWLVAPMQMPNGELQERSKGTPQGGIVSPVLANLFLHYVFDKWLSKHYPRVPWCRYADDGLLHCNSLLEAQDMLEVLKLRFNACGLDLHPTKTKIVYCKDTSRKGGYKTTSFDFLGYTFRARRVKGKIRNNLFMSFSPAVSKSALKTMRYRIRKLRVRCRTEMSINEIAKWLNPIIQGWIYYYGRFHRSALTAIGRHINLTLIRWARRKYKRLRKHKINACKFIGNLIEQAPHLFAHWRAGLGTALA
>NZ_CP046816.1|WP_078927662.1|360705_361839_-|ISAs1-family-transposase
MSELINPFMHFQIIKDYRQESKVEHKLSDIILLTICGVLSGQDGWDGIIDFGNARLDFLKRYGHFEAGIPSADTLSRVMGMINPVALQRSFIAWMKDCHTLTDGEVIAIDGKTLRSSYDRSKGKGTIHMVNAFATANGMSIGQLKVDSKSNEITAIPKLLDLLDVKGCLITIDAMGCQKKIAQKILDKEADYLLAVKGNQGMLEQAFDDYFRMSMLQDFDGSSYSTQEKSHGRIETRVALVNRDLSVLGDIEHEWPGLKSMGIVASIRQESAVATEQDVSIRYYICSKELEAQTLLEATRSHWGVEVMHWSLDTAFCEDNSRIRADDRAEAFARIRQICLNLLKSETTFKGGIKRKRMNCAMDENYLSKVLESLTGQ
>NZ_CP046816.1|WP_139364809.1|359896_360664_-|hypothetical-protein
MAFFGLGGYLRLRQASLSAVVCVACPLMRRYAFGGNMWNIRELKYHLDLLGEQPEHYIEYLDSVCRIIKIFEFHKVEAFSLISRLDSDDPEMAMRLVFSMGSERTDVENEVISAQAHLHAALQNVRSMYDILAQLLNALLVHEPIPIHSCDICKVCKSLPNGKVKTELEKILASFEYQYVNSFVNTIKHRNLVQFNRQLDLLESRASIRIKPFSYAGCFYEQKWAIDVLKYGLDVKNQLIEIGQLLNSECGVRNA
>NZ_CP046816.1|WP_115173889.1|372589_372679_-|hypothetical-protein
MAFLLCVGFCGYGVMRKVGSSVGCPLSGR
>NZ_CP046816.1|WP_078927655.1|372883_373306_-|hypothetical-protein
MHTPIKFYITLPFDLFRLGRKSKAKFDYIRTSPPRDMDEVWDLKIYSKNGVEFVDCKSGGLSLFNYRNPRFGTLWWKIPQNTKMPNGLHVSLDDGGSNGKHHFTIRPLQDMPLSLYLIKLQQLESSARPCFINSPNSQVG
>NZ_CP046816.1|WP_115173888.1|373549_374578_-|IS630-family-transposase
MKIILTSQQKQQLEQMHDSTRDGRVRDRIKAVLLASEGWSQAMISQALRIHESTVARHLSDYVLSEKLKPENGGSQSRLSAGQTMQLIEHLAEKMYFHTHQIVSYVQAEFGIRYTVAGMNKWLHHHGFSYKKPKGVPHKFNPERQQAFIEHYNETLRNSEDPVLFMDAVHPTQSTKLSYGWIRKGQDKVIETTGSRTRLNIIGALPLQNIGATVTDTYDTINSESIVRFFWKLKKEHYPLEQQVHLVLDGAAYHQSELVRNAAKVLNIELHYLPPYSPNLNPIERLWKVMNEHVRNNIYFRSKAEFTTAINEFFNVTLPKVAGSLVSRISDNFQILKPASSS
>NZ_CP046816.1|WP_078927661.1|374627_375011_-|hypothetical-protein
MIEFLVNVFLSVLSGIYAGLVVARFVKFEEIRTRIKKVIYNIDFINDGPNGEYILIDRGNSNDLLLYISELLYLQHKSAANIVGGLMTSINHSKANPHQLTGDINDFYPKWQEIARKLKPNIWVLYP
>NZ_CP046816.1|WP_078927660.1|375157_375988_-|DUF4238-domain-containing-protein
MSKLSEKHHFIPVFYQKGFLSSKSELFAYKKKFGSIKNWSPSQIMYEKNLHTISIGGEKTVMLEEFYSQMEGLFNEYISLISDNINNKNLLAELTNDGDFQRLAKLMVAIQFWRTPCRRQQAIDYAPKLVSLYDSADEEIKEIFDNDRKFIRFLSKRAKKNYSLKVIQFLLLPLLTFDLSTKVIKLNLFKASKDMKFISSDRPVVFDAIEDLFNFKSFLFPFSKELLLVGTEKDVKVINIEKVNFMIANKASEVVISGSKEQLEHLKDRLNQPATV
>NZ_CP046816.1|WP_158116599.1|376037_376889_-|IS3-family-transposase
MKYEYIESYVGEYKVTHMCRALDVSPSGYYKWLNREPSERSKRRCRFEQLVMCTFAKHRARYGSVRIAEALNESGYTCCVNYIADIMKEKGIKARNGIGFKYTKDVAAMTNVADNLLRRDFEAKRPNQKWVTDITYIWVKSRWLYLATVLDLHSRRIVGWSLDTTMTVQLITNALKMAFKSRKPAKGVIIHSDRGVQYRAHDYQDFMRKHGGVPSMSRKGNCWDNAVMESFYSRLKVELIYAEDYQTIEEARMGIFEYIEIYYNRNRKHSALGYVSPVEFESV
>NZ_CP046816.1|WP_115173886.1|377735_377912_-|DUF3265-domain-containing-protein
MKSFSRKANKRFKRDNQRVAFLLCVGFCGYGVMRKLGSGVGCPLTGRYVTVEKKTTMY
>NZ_CP046816.1|WP_078927626.1|377908_378283_-|hypothetical-protein
MEELDWSRLIPMSLSALAACVSVFYASKARRAQIKQVENKFEIEQLNDLIEKLKIANAIETHPYDYDDDTFVNGRNLDDVPSKIAKLMQNSLISEALTKTEWELPITNLQSKIDQLCAVRKKLL
>NZ_CP046816.1|WP_078927627.1|378440_379643_-|DUF3644-domain-containing-protein
MVRQDKRILLLEFFREQENKSASFTFQQAADATGYNPKSVGKYISEKLNGTYIFKSDKGGWVSEGLSQVSNDDFIRLMSQSTSARKLTPNEKMYQKLIKCSLDAFILALEVYNRPSLSNRVEAFTIMMVNAWELFLKAEILDALGSEKVFYKNGRSISISDALPLRLKNNDPVRLNIETLIQLRDQATHLLIPELQPQLSRLFQANVLNYQERYRNQMGNSPLAGQSVGMLSLVLDGPEPEIGVIKECYGDITASEVASFLKQFETNAKEINSDKYSISIEYKLALTKNPSNADLTLSVGYNGQQAVIITQAKDLNTTHPHTTNEAINKINSILGSKKINRHSFQAICYKHKIKQDNNSTHHNFTDIHRYSEAFVTWVVKNITEQKGWLESALECYKNRK
>NZ_CP046816.1|WP_078927628.1|379786_380899_-|hypothetical-protein
MGKKLILDVPSLKLGDVILTSEKGFASIGVRAATLSKYSHAAIYVGGTMIEATLGGVFSKNPQRLLFDSEKQVAVYRYRAELDETQIKNVCDYARSKTASLYTISEAVTLRIREILNKPESRKQFCSRLVALSYSDNGINLGNIRNPAYCTPKQLSLCKVFYKVNNIVREAEEHEIAFAKTDDPNILHQKDTIAWVNKVRELVKIEGLSKDFDIQSITDVDEFLKLNHQYDELVVSYMNSGGYLTHYNFDTKRNPYRYNLTLLDSVVKERNDKHAFFNEQLSKELDIINLYSENLNRYLNYYVHNNLSYYREHCLLYMNLLTGIYVRAKFLHQVSKKYRNYDVAYASSEVLRIAAVNCGKGKEILGVQGA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP046816_4	4.7\|372143\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	372143-372174	32	NZ_CP040822	Paraoceanicella profunda strain D4M1 plasmid pD4M1D, complete sequence	131424-131455	6	0.812
NZ_CP046816_2	2.13\|290406\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290406-290437	32	MH649021	Inoviridae sp. isolate ctii000, complete genome	5505-5536	7	0.781
NZ_CP046816_2	2.13\|290406\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290406-290437	32	MN693995	Marine virus AFVG_250M873, complete genome	36158-36189	7	0.781
NZ_CP046816_2	2.13\|290406\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290406-290437	32	MN693748	Marine virus AFVG_250M1092, complete genome	36102-36133	7	0.781
NZ_CP046816_2	2.13\|290406\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290406-290437	32	MN693610	Marine virus AFVG_250M347, complete genome	17608-17639	7	0.781
NZ_CP046816_2	2.13\|290406\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290406-290437	32	MN693983	Marine virus AFVG_250M348, complete genome	36143-36174	7	0.781
NZ_CP046816_2	2.13\|290406\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290406-290437	32	MN694187	Marine virus AFVG_250M1090, complete genome	18289-18320	7	0.781
NZ_CP046816_2	2.13\|290406\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290406-290437	32	MN694702	Marine virus AFVG_250M1088, complete genome	36114-36145	7	0.781
NZ_CP046816_2	2.13\|290406\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290406-290437	32	MN693937	Marine virus AFVG_250M350, complete genome	36087-36118	7	0.781
NZ_CP046816_2	2.13\|290406\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290406-290437	32	MN693780	Marine virus AFVG_250M1089, complete genome	35658-35689	7	0.781
NZ_CP046816_2	2.13\|290406\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290406-290437	32	MN694535	Marine virus AFVG_250M1087, complete genome	35647-35678	7	0.781
NZ_CP046816_2	2.13\|290406\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290406-290437	32	MN694384	Marine virus AFVG_250M349, complete genome	35898-35929	7	0.781
NZ_CP046816_2	2.13\|290406\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290406-290437	32	MN694622	Marine virus AFVG_250M1091, complete genome	36285-36316	7	0.781
NZ_CP046816_3	3.2\|316778\|32\|NZ_CP046816\|CRISPRCasFinder,CRT,PILER-CR	316778-316809	32	NZ_KT897276	Clostridium botulinum strain INGR16-02E1 plasmid pINGR16-02E1, complete sequence	27358-27389	7	0.781
NZ_CP046816_3	3.2\|316778\|32\|NZ_CP046816\|CRISPRCasFinder,CRT,PILER-CR	316778-316809	32	NZ_KT897280	Clostridium botulinum strain FI1111E1 plasmid pFI1111E1, complete sequence	26271-26302	7	0.781
NZ_CP046816_3	3.2\|316778\|32\|NZ_CP046816\|CRISPRCasFinder,CRT,PILER-CR	316778-316809	32	NZ_KT897277	Clostridium botulinum strain ST0210E1 plasmid pST0210E1, complete sequence	27358-27389	7	0.781
NZ_CP046816_3	3.2\|316778\|32\|NZ_CP046816\|CRISPRCasFinder,CRT,PILER-CR	316778-316809	32	NZ_KT897278	Clostridium botulinum strain FWSKR40E1 plasmid pFWSKR40E1, complete sequence	26271-26302	7	0.781
NZ_CP046816_3	3.2\|316778\|32\|NZ_CP046816\|CRISPRCasFinder,CRT,PILER-CR	316778-316809	32	NZ_KT897279	Clostridium botulinum strain SWKR38E2 plasmid pSWKR38E2, complete sequence	26271-26302	7	0.781
NZ_CP046816_4	4.5\|372023\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	372023-372054	32	CP033531	Acinetobacter pittii strain 2014S07-126 plasmid p2014S07-126-1, complete sequence	124253-124284	7	0.781
NZ_CP046816_4	4.5\|372023\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	372023-372054	32	NZ_CP029396	Acinetobacter defluvii strain WCHA30 plasmid pOXA58_010030, complete sequence	348411-348442	7	0.781
NZ_CP046816_4	4.5\|372023\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	372023-372054	32	NZ_CP032285	Acinetobacter sp. WCHA55 plasmid pOXA58_010055, complete sequence	291877-291908	7	0.781
NZ_CP046816_4	4.5\|372023\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	372023-372054	32	NZ_CP043309	Acinetobacter johnsonii strain Acsw19 plasmid pAcsw19-2, complete sequence	345622-345653	7	0.781
NZ_CP046816_4	4.9\|372263\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	372263-372294	32	MN856087	Bacteriophage sp. isolate 245, complete genome	4612-4643	7	0.781
NZ_CP046816_2	2.12\|290346\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290346-290377	32	MN694138	Marine virus AFVG_250M1080, complete genome	11918-11949	8	0.75
NZ_CP046816_2	2.12\|290346\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290346-290377	32	MT774411	CrAssphage cr273_1, complete genome	24566-24597	8	0.75
NZ_CP046816_2	2.12\|290346\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290346-290377	32	MN694327	Marine virus AFVG_250M339, complete genome	31149-31180	8	0.75
NZ_CP046816_2	2.12\|290346\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290346-290377	32	MT774410	CrAssphage cr272_1, complete genome	12948-12979	8	0.75
NZ_CP046816_2	2.13\|290406\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290406-290437	32	AP014254	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S23-C71, * SEQUENCING IN PROGRESS *	13924-13955	8	0.75
NZ_CP046816_3	3.2\|316778\|32\|NZ_CP046816\|CRISPRCasFinder,CRT,PILER-CR	316778-316809	32	NZ_KT897275	Clostridium botulinum strain IFR 12/29 plasmid p12/29, complete sequence	27393-27424	8	0.75
NZ_CP046816_3	3.2\|316778\|32\|NZ_CP046816\|CRISPRCasFinder,CRT,PILER-CR	316778-316809	32	KX190833	Bacillus phage vB_BtS_BMBtp14, complete genome	42682-42713	8	0.75
NZ_CP046816_4	4.1\|371783\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	371783-371814	32	NZ_CP015331	Borrelia hermsii HS1 isolate Browne Mountain plasmid lpN31, complete sequence	4858-4889	8	0.75
NZ_CP046816_2	2.2\|289745\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	289745-289776	32	NC_009621	Sinorhizobium medicae WSM419 plasmid pSMED02, complete sequence	102575-102606	9	0.719
NZ_CP046816_2	2.8\|290105\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290105-290136	32	NZ_CP032091	Pseudoalteromonas donghaensis strain HJ51 plasmid unnamed1, complete sequence	641567-641598	9	0.719
NZ_CP046816_2	2.9\|290165\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290165-290196	32	LR134125	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5	319532-319563	9	0.719
NZ_CP046816_2	2.13\|290406\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290406-290437	32	MT701590	Klebsiella phage Miami, complete genome	108528-108559	9	0.719
NZ_CP046816_2	2.15\|290526\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290526-290557	32	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	1250301-1250332	9	0.719
NZ_CP046816_3	3.2\|316778\|32\|NZ_CP046816\|CRISPRCasFinder,CRT,PILER-CR	316778-316809	32	NZ_CP031650	Pantoea agglomerans strain TH81 plasmid unnamed1, complete sequence	232114-232145	9	0.719
NZ_CP046816_3	3.4\|316898\|32\|NZ_CP046816\|CRISPRCasFinder,CRT,PILER-CR	316898-316929	32	LC487410	Vibrio phage KIT04 DNA, complete genome	89731-89762	9	0.719
NZ_CP046816_4	4.7\|372143\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	372143-372174	32	NC_010392	Phage Gifsy-1, complete genome	15319-15350	9	0.719
NZ_CP046816_4	4.9\|372263\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	372263-372294	32	NZ_CP017244	Rhizobium etli 8C-3 plasmid pRsp8C3c, complete sequence	36021-36052	9	0.719
NZ_CP046816_2	2.11\|290286\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290286-290317	32	MK448721	Streptococcus phage Javan263, complete genome	15416-15447	10	0.688
NZ_CP046816_3	3.2\|316778\|32\|NZ_CP046816\|CRISPRCasFinder,CRT,PILER-CR	316778-316809	32	NZ_CP017941	Phyllobacterium zundukense strain Tri-48 plasmid unnamed1, complete sequence	14479-14510	10	0.688
NZ_CP046816_3	3.4\|316898\|32\|NZ_CP046816\|CRISPRCasFinder,CRT,PILER-CR	316898-316929	32	AP014333	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S36-C55, * SEQUENCING IN PROGRESS *	17832-17863	10	0.688
NZ_CP046816_4	4.4\|371963\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	371963-371994	32	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	1882764-1882795	10	0.688
NZ_CP046816_4	4.4\|371963\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	371963-371994	32	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1886431-1886462	10	0.688
NZ_CP046816_4	4.4\|371963\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	371963-371994	32	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	120428-120459	10	0.688
NZ_CP046816_4	4.4\|371963\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	371963-371994	32	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	120426-120457	10	0.688
NZ_CP046816_4	4.4\|371963\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	371963-371994	32	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	1859282-1859313	10	0.688
NZ_CP046816_2	2.8\|290105\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290105-290136	32	NZ_CP025861	Escherichia coli strain 504239 plasmid p504239_155, complete sequence	40928-40959	11	0.656
NZ_CP046816_2	2.8\|290105\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290105-290136	32	NZ_CP025905	Escherichia coli strain 300709 plasmid p300709_60, complete sequence	56539-56570	11	0.656
NZ_CP046816_2	2.8\|290105\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290105-290136	32	NZ_CP013192	Escherichia coli strain FORC_031 plasmid pFORC31.2, complete sequence	31541-31572	11	0.656
NZ_CP046816_2	2.8\|290105\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290105-290136	32	NZ_EF595770	Escherichia coli strain E9034A plasmid pE9034A, complete sequence	3616-3647	11	0.656
NZ_CP046816_2	2.8\|290105\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290105-290136	32	NC_014233	Escherichia coli ETEC 1392/75 plasmid p557, complete sequence	37720-37751	11	0.656
NZ_CP046816_2	2.8\|290105\|32\|NZ_CP046816\|PILER-CR,CRISPRCasFinder,CRT	290105-290136	32	NZ_CP024235	Escherichia coli O6:H16 strain 2014EL-1346-6 plasmid unnamed3, complete sequence	32103-32134	11	0.656

1. spacer 4.7|372143|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040822 (Paraoceanicella profunda strain D4M1 plasmid pD4M1D, complete sequence) position: , mismatch: 6, identity: 0.812

tcaagtttcgaattgtaatccgc-acgccggaa	CRISPR spacer
acacgcttcgaattgtaatccgcaacacccga-	Protospacer
 ** *.***************** **.** **

2. spacer 2.13|290406|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to MH649021 (Inoviridae sp. isolate ctii000, complete genome) position: , mismatch: 7, identity: 0.781

aagcaatatcaacacgagtaattttaaccgaa	CRISPR spacer
aagcaatatcaacacgggtaattttggtgtca	Protospacer
****************.********...   *

3. spacer 2.13|290406|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to MN693995 (Marine virus AFVG_250M873, complete genome) position: , mismatch: 7, identity: 0.781

aagcaatatcaacacgagtaattttaaccgaa	CRISPR spacer
aagcaatatcaataagagtaatttcatcacca	Protospacer
************.* *********.* *   *

4. spacer 2.13|290406|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to MN693748 (Marine virus AFVG_250M1092, complete genome) position: , mismatch: 7, identity: 0.781

aagcaatatcaacacgagtaattttaaccgaa	CRISPR spacer
aagcaatatcaataagagtaatttcatcacca	Protospacer
************.* *********.* *   *

5. spacer 2.13|290406|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to MN693610 (Marine virus AFVG_250M347, complete genome) position: , mismatch: 7, identity: 0.781

aagcaatatcaacacgagtaattttaaccgaa	CRISPR spacer
aagcaatatcaataagagtaatttcatcacca	Protospacer
************.* *********.* *   *

6. spacer 2.13|290406|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to MN693983 (Marine virus AFVG_250M348, complete genome) position: , mismatch: 7, identity: 0.781

aagcaatatcaacacgagtaattttaaccgaa	CRISPR spacer
aagcaatatcaataagagtaatttcatcacca	Protospacer
************.* *********.* *   *

7. spacer 2.13|290406|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to MN694187 (Marine virus AFVG_250M1090, complete genome) position: , mismatch: 7, identity: 0.781

aagcaatatcaacacgagtaattttaaccgaa	CRISPR spacer
aagcaatatcaataagagtaatttcatcacca	Protospacer
************.* *********.* *   *

8. spacer 2.13|290406|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to MN694702 (Marine virus AFVG_250M1088, complete genome) position: , mismatch: 7, identity: 0.781

aagcaatatcaacacgagtaattttaaccgaa	CRISPR spacer
aagcaatatcaataagagtaatttcatcacca	Protospacer
************.* *********.* *   *

9. spacer 2.13|290406|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to MN693937 (Marine virus AFVG_250M350, complete genome) position: , mismatch: 7, identity: 0.781

aagcaatatcaacacgagtaattttaaccgaa	CRISPR spacer
aagcaatatcaataagagtaatttcatcacca	Protospacer
************.* *********.* *   *

10. spacer 2.13|290406|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to MN693780 (Marine virus AFVG_250M1089, complete genome) position: , mismatch: 7, identity: 0.781

aagcaatatcaacacgagtaattttaaccgaa	CRISPR spacer
aagcaatatcaataagagtaatttcatcacca	Protospacer
************.* *********.* *   *

11. spacer 2.13|290406|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to MN694535 (Marine virus AFVG_250M1087, complete genome) position: , mismatch: 7, identity: 0.781

aagcaatatcaacacgagtaattttaaccgaa	CRISPR spacer
aagcaatatcaataagagtaatttcatcacca	Protospacer
************.* *********.* *   *

12. spacer 2.13|290406|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to MN694384 (Marine virus AFVG_250M349, complete genome) position: , mismatch: 7, identity: 0.781

aagcaatatcaacacgagtaattttaaccgaa	CRISPR spacer
aagcaatatcaataagagtaatttcatcacca	Protospacer
************.* *********.* *   *

13. spacer 2.13|290406|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to MN694622 (Marine virus AFVG_250M1091, complete genome) position: , mismatch: 7, identity: 0.781

aagcaatatcaacacgagtaattttaaccgaa	CRISPR spacer
aagcaatatcaataagagtaatttcatcacca	Protospacer
************.* *********.* *   *

14. spacer 3.2|316778|32|NZ_CP046816|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KT897276 (Clostridium botulinum strain INGR16-02E1 plasmid pINGR16-02E1, complete sequence) position: , mismatch: 7, identity: 0.781

agggataatattatttcctgttattttctctt	CRISPR spacer
agaaataataatatttcctgatatttttccta	Protospacer
**..****** ********* ******..**

15. spacer 3.2|316778|32|NZ_CP046816|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KT897280 (Clostridium botulinum strain FI1111E1 plasmid pFI1111E1, complete sequence) position: , mismatch: 7, identity: 0.781

agggataatattatttcctgttattttctctt	CRISPR spacer
agaaataataatatttcctgatatttttccta	Protospacer
**..****** ********* ******..**

16. spacer 3.2|316778|32|NZ_CP046816|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KT897277 (Clostridium botulinum strain ST0210E1 plasmid pST0210E1, complete sequence) position: , mismatch: 7, identity: 0.781

agggataatattatttcctgttattttctctt	CRISPR spacer
agaaataataatatttcctgatatttttccta	Protospacer
**..****** ********* ******..**

17. spacer 3.2|316778|32|NZ_CP046816|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KT897278 (Clostridium botulinum strain FWSKR40E1 plasmid pFWSKR40E1, complete sequence) position: , mismatch: 7, identity: 0.781

agggataatattatttcctgttattttctctt	CRISPR spacer
agaaataataatatttcctgatatttttccta	Protospacer
**..****** ********* ******..**

18. spacer 3.2|316778|32|NZ_CP046816|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KT897279 (Clostridium botulinum strain SWKR38E2 plasmid pSWKR38E2, complete sequence) position: , mismatch: 7, identity: 0.781

agggataatattatttcctgttattttctctt	CRISPR spacer
agaaataataatatttcctgatatttttccta	Protospacer
**..****** ********* ******..**

19. spacer 4.5|372023|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to CP033531 (Acinetobacter pittii strain 2014S07-126 plasmid p2014S07-126-1, complete sequence) position: , mismatch: 7, identity: 0.781

gttctcgtggttttgctcctaaagtgcgtaat	CRISPR spacer
gggatcagggtgttgctcctagagtgcgtaat	Protospacer
*   **. *** *********.**********

20. spacer 4.5|372023|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029396 (Acinetobacter defluvii strain WCHA30 plasmid pOXA58_010030, complete sequence) position: , mismatch: 7, identity: 0.781

gttctcgtggttttgctcctaaagtgcgtaat	CRISPR spacer
gggatcagggtgttgctcctagagtgcgtaat	Protospacer
*   **. *** *********.**********

21. spacer 4.5|372023|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032285 (Acinetobacter sp. WCHA55 plasmid pOXA58_010055, complete sequence) position: , mismatch: 7, identity: 0.781

gttctcgtggttttgctcctaaagtgcgtaat	CRISPR spacer
gggatcagggtgttgctcctagagtgcgtaat	Protospacer
*   **. *** *********.**********

22. spacer 4.5|372023|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043309 (Acinetobacter johnsonii strain Acsw19 plasmid pAcsw19-2, complete sequence) position: , mismatch: 7, identity: 0.781

gttctcgtggttttgctcctaaagtgcgtaat	CRISPR spacer
gggatcagggtgttgctcctagagtgcgtaat	Protospacer
*   **. *** *********.**********

23. spacer 4.9|372263|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to MN856087 (Bacteriophage sp. isolate 245, complete genome) position: , mismatch: 7, identity: 0.781

ctttctccaactcaagctctggttctggttta	CRISPR spacer
ggtcatccaactcaagctctggttctgattgg	Protospacer
  *. **********************.** .

24. spacer 2.12|290346|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to MN694138 (Marine virus AFVG_250M1080, complete genome) position: , mismatch: 8, identity: 0.75

tcaccacggtaatcactatcaatcacaccaat	CRISPR spacer
gcagctttgtaatcactatcaattccaccaag	Protospacer
 ** * . ***************. ******

25. spacer 2.12|290346|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to MT774411 (CrAssphage cr273_1, complete genome) position: , mismatch: 8, identity: 0.75

tcaccacggtaatcactatcaatcacaccaat	CRISPR spacer
tcaccacgataatcactatcgattgtagacat	Protospacer
********.***********.**...*   **

26. spacer 2.12|290346|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to MN694327 (Marine virus AFVG_250M339, complete genome) position: , mismatch: 8, identity: 0.75

tcaccacggtaatcactatcaatcacaccaat	CRISPR spacer
gcagctttgtaatcactatcaattccaccaag	Protospacer
 ** * . ***************. ******

27. spacer 2.12|290346|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to MT774410 (CrAssphage cr272_1, complete genome) position: , mismatch: 8, identity: 0.75

tcaccacggtaatcactatcaatcacaccaat	CRISPR spacer
tcaccacgataatcactatcgattgtagacat	Protospacer
********.***********.**...*   **

28. spacer 2.13|290406|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to AP014254 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S23-C71, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 8, identity: 0.75

aagcaatatcaacacgagtaattttaaccgaa	CRISPR spacer
atacaatatcaacactagtaactttaccaaat	Protospacer
* .************ *****.**** * .*

29. spacer 3.2|316778|32|NZ_CP046816|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KT897275 (Clostridium botulinum strain IFR 12/29 plasmid p12/29, complete sequence) position: , mismatch: 8, identity: 0.75

agggataatattatttcctgttattttctctt	CRISPR spacer
ataaataataatatttcctgatatttttccta	Protospacer
* ..****** ********* ******..**

30. spacer 3.2|316778|32|NZ_CP046816|CRISPRCasFinder,CRT,PILER-CR matches to KX190833 (Bacillus phage vB_BtS_BMBtp14, complete genome) position: , mismatch: 8, identity: 0.75

agggataatattatttcctgttattttctctt	CRISPR spacer
atctaaactaatatttcctgttattttttctc	Protospacer
*   * * ** ****************.***.

31. spacer 4.1|371783|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015331 (Borrelia hermsii HS1 isolate Browne Mountain plasmid lpN31, complete sequence) position: , mismatch: 8, identity: 0.75

tttctgggacatttgaagctgaaaa--gatgatc	CRISPR spacer
aatctggtacagttgaagctgaaaaacattga--	Protospacer
  ***** *** *************  . ***

32. spacer 2.2|289745|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to NC_009621 (Sinorhizobium medicae WSM419 plasmid pSMED02, complete sequence) position: , mismatch: 9, identity: 0.719

tacgatgccgtccaagagggaatct-tgatgtt	CRISPR spacer
gtcgatgccgtccaagagcggatctccggcgc-	Protospacer
  **************** *.**** .*..*.

33. spacer 2.8|290105|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032091 (Pseudoalteromonas donghaensis strain HJ51 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

atcgagtggcgaatttatcgctattgccgagc	CRISPR spacer
gtcaccaaacgaatttatcgccattgcagagc	Protospacer
.**.   ..************.***** ****

34. spacer 2.9|290165|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to LR134125 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5) position: , mismatch: 9, identity: 0.719

aaggcattgcggagtatttgcttgttggtgag	CRISPR spacer
ataatttgccggagtatttgcttgttagtcag	Protospacer
* ... *  *****************.** **

35. spacer 2.13|290406|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to MT701590 (Klebsiella phage Miami, complete genome) position: , mismatch: 9, identity: 0.719

aagcaatatcaacacgagtaattttaaccgaa	CRISPR spacer
ataaaatctcatcacgagtaattttaatatac	Protospacer
* . *** *** ***************.  *

36. spacer 2.15|290526|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 9, identity: 0.719

gatatgggttatcacgcgagcttggcgaatcg	CRISPR spacer
ctcgcgggttatcacgcgagctcggcaaatac	Protospacer
  ...*****************.***.***

37. spacer 3.2|316778|32|NZ_CP046816|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031650 (Pantoea agglomerans strain TH81 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

agggataatattatttcctgttattttctctt	CRISPR spacer
ttatataatatagtttcctgttattttttatc	Protospacer
  . ******* .**************.* *.

38. spacer 3.4|316898|32|NZ_CP046816|CRISPRCasFinder,CRT,PILER-CR matches to LC487410 (Vibrio phage KIT04 DNA, complete genome) position: , mismatch: 9, identity: 0.719

gttgcgtgtgatattttagctgcctcattttg	CRISPR spacer
gctgcttgtgatgttttagctgccttttcaga	Protospacer
*.*** ******.************. *.  .

39. spacer 4.7|372143|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to NC_010392 (Phage Gifsy-1, complete genome) position: , mismatch: 9, identity: 0.719

tcaagtttcgaattgtaatccgcacgccggaa	CRISPR spacer
tcaactttcgcattgtaatccgcccactcagc	Protospacer
**** ***** ************ *.*. ..

40. spacer 4.9|372263|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017244 (Rhizobium etli 8C-3 plasmid pRsp8C3c, complete sequence) position: , mismatch: 9, identity: 0.719

ctttctccaactcaagctctggttctggttta	CRISPR spacer
gcttctccaactcatgatctggttcaatttgg	Protospacer
 .************ * ******** . ** .

41. spacer 2.11|290286|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to MK448721 (Streptococcus phage Javan263, complete genome) position: , mismatch: 10, identity: 0.688

gtgacgttcaaaataaaccggacgttttttag	CRISPR spacer
tttttaatcaaaataacccggacgtctttttc	Protospacer
 *  .. ********* ********.****

42. spacer 3.2|316778|32|NZ_CP046816|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017941 (Phyllobacterium zundukense strain Tri-48 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

agggataatattatttcctgttattttctctt	CRISPR spacer
taacatcataatatttcctgttattttgctta	Protospacer
 .. ** *** **************** ..*

43. spacer 3.4|316898|32|NZ_CP046816|CRISPRCasFinder,CRT,PILER-CR matches to AP014333 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S36-C55, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 10, identity: 0.688

gttgcgtgtgatattttagctgcctcattttg	CRISPR spacer
gttgcgtctaatattttagctgcaatcgtaaa	Protospacer
******* *.*************  .  *  .

44. spacer 4.4|371963|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

ataattgtctcttgagttctgtcgctcagtcg	CRISPR spacer
ttggcgaaatctttagtcctgtcgctcagtcg	Protospacer
 *... .  **** ***.**************

45. spacer 4.4|371963|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

ataattgtctcttgagttctgtcgctcagtcg	CRISPR spacer
ttggcgaaatctttagtcctgtcgctcagtcg	Protospacer
 *... .  **** ***.**************

46. spacer 4.4|371963|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 10, identity: 0.688

ataattgtctcttgagttctgtcgctcagtcg	CRISPR spacer
ttggcgaaatctttagtcctgtcgctcagtcg	Protospacer
 *... .  **** ***.**************

47. spacer 4.4|371963|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

ataattgtctcttgagttctgtcgctcagtcg	CRISPR spacer
ttggcgaaatctttagtcctgtcgctcagtcg	Protospacer
 *... .  **** ***.**************

48. spacer 4.4|371963|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 10, identity: 0.688

ataattgtctcttgagttctgtcgctcagtcg	CRISPR spacer
ttggcgaaatctttagtcctgtcgctcagtcg	Protospacer
 *... .  **** ***.**************

49. spacer 2.8|290105|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025861 (Escherichia coli strain 504239 plasmid p504239_155, complete sequence) position: , mismatch: 11, identity: 0.656

atcgagtggcgaatttatcgctattgccgagc	CRISPR spacer
catttctggcgactttatcgctattggcggtg	Protospacer
  .   ****** ************* **.

50. spacer 2.8|290105|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025905 (Escherichia coli strain 300709 plasmid p300709_60, complete sequence) position: , mismatch: 11, identity: 0.656

atcgagtggcgaatttatcgctattgccgagc	CRISPR spacer
catttctggcgactttatcgctattggcggtg	Protospacer
  .   ****** ************* **.

51. spacer 2.8|290105|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013192 (Escherichia coli strain FORC_031 plasmid pFORC31.2, complete sequence) position: , mismatch: 11, identity: 0.656

atcgagtggcgaatttatcgctattgccgagc	CRISPR spacer
catttctggcgactttatcgctattggcggtg	Protospacer
  .   ****** ************* **.

52. spacer 2.8|290105|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to NZ_EF595770 (Escherichia coli strain E9034A plasmid pE9034A, complete sequence) position: , mismatch: 11, identity: 0.656

atcgagtggcgaatttatcgctattgccgagc	CRISPR spacer
catttctggcgactttatcgctattggcggtg	Protospacer
  .   ****** ************* **.

53. spacer 2.8|290105|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to NC_014233 (Escherichia coli ETEC 1392/75 plasmid p557, complete sequence) position: , mismatch: 11, identity: 0.656

atcgagtggcgaatttatcgctattgccgagc	CRISPR spacer
catttctggcgactttatcgctattggcggtg	Protospacer
  .   ****** ************* **.

54. spacer 2.8|290105|32|NZ_CP046816|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024235 (Escherichia coli O6:H16 strain 2014EL-1346-6 plasmid unnamed3, complete sequence) position: , mismatch: 11, identity: 0.656

atcgagtggcgaatttatcgctattgccgagc	CRISPR spacer
catttctggcgactttatcgctattggcggtg	Protospacer
  .   ****** ************* **.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

253360 : 288839

Pseudomonas_phage(54.55%)

transposase,integrase

attL 258106:258125|attR 289008:289027

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_078927662.1\|253360_254494_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_115173883.1\|254728_256054_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	2.0e-30	31.3
WP_115173912.1\|256577_256859_-	hypothetical protein	NA	NA	NA	NA
WP_115173888.1\|256883_257912_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_115173911.1\|257823_258096_-	hypothetical protein	NA	NA	NA	NA
258106:258125	attL	NA	NA	NA	NA
WP_115173891.1\|258214_258730_-	hypothetical protein	NA	NA	NA	NA
WP_158142138.1\|259327_260179_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	8.3e-54	42.4
WP_078927561.1\|261161_261404_-	hypothetical protein	NA	NA	NA	NA
WP_078927560.1\|261407_261959_-	hypothetical protein	NA	NA	NA	NA
WP_078927559.1\|263688_264360_-	helix-turn-helix transcriptional regulator	A0A2R2ZGJ3	Clostridioides_phage	1.5e-05	32.7
WP_078927558.1\|264431_264650_+	hypothetical protein	NA	NA	NA	NA
WP_078927557.1\|264667_265018_+	hypothetical protein	NA	NA	NA	NA
WP_078927556.1\|265004_265337_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_078927555.1\|265338_266310_+	MarR family transcriptional regulator	J9SW46	Pseudomonas_phage	9.8e-19	35.0
WP_078927554.1\|266316_268074_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	Q5ZR04	Pseudomonas_phage	5.3e-87	33.2
WP_115173908.1\|268003_269158_+	AAA family ATPase	J9SNL1	Pseudomonas_phage	5.4e-48	37.8
WP_078927552.1\|269160_269619_+	hypothetical protein	NA	NA	NA	NA
WP_078927551.1\|270092_270359_+	hypothetical protein	NA	NA	NA	NA
WP_078927550.1\|270355_270766_+	hypothetical protein	NA	NA	NA	NA
WP_078927549.1\|271011_271359_+	hypothetical protein	NA	NA	NA	NA
WP_078927548.1\|271372_271951_+	hypothetical protein	NA	NA	NA	NA
WP_139364796.1\|271989_272325_+	hypothetical protein	NA	NA	NA	NA
WP_078927546.1\|272404_275293_+	hypothetical protein	A0A0H5AWE4	Pseudomonas_phage	3.3e-46	32.5
WP_158116599.1\|275508_276360_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	4.4e-55	42.7
WP_078927572.1\|276861_277431_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_078927571.1\|278540_279248_+	hypothetical protein	NA	NA	NA	NA
WP_078927570.1\|279244_279817_+	hypothetical protein	NA	NA	NA	NA
WP_078927569.1\|280114_282265_-	hypothetical protein	A5LH58	Enterobacteria_phage	2.2e-103	32.8
WP_078927568.1\|282707_283193_-	hypothetical protein	NA	NA	NA	NA
WP_078927576.1\|283192_284071_-	hypothetical protein	NA	NA	NA	NA
WP_115173907.1\|284187_285756_-	replication endonuclease	F1BUS0	Erwinia_phage	5.7e-77	42.1
WP_115173906.1\|285752_286004_-	hypothetical protein	NA	NA	NA	NA
WP_078927575.1\|285996_286233_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_115173905.1\|286311_287283_-	hypothetical protein	NA	NA	NA	NA
WP_078927578.1\|287633_288839_-\|integrase	site-specific integrase	A0A0S2SYQ7	Pseudomonas_phage	1.4e-27	32.8
289008:289027	attR	NA	NA	NA	NA

DBSCAN-SWA_2

300248 : 337925

Shigella_phage(40.0%)

integrase,transposase

attL 290074:290105|attR 317047:317078

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
290074:290105	attL	NA	NA	NA	NA
WP_078927564.1\|300248_301109_-\|integrase	site-specific integrase	A0A0S2SYQ7	Pseudomonas_phage	4.6e-28	33.2
WP_078927563.1\|301089_302229_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_115173883.1\|304437_305763_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	2.0e-30	31.3
WP_078927605.1\|306905_307715_-	hypothetical protein	NA	NA	NA	NA
WP_078927604.1\|307704_308148_-	hypothetical protein	NA	NA	NA	NA
WP_078927603.1\|308175_308301_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_078927602.1\|308282_308714_-	hypothetical protein	NA	NA	NA	NA
WP_078927601.1\|308868_309192_-	hypothetical protein	NA	NA	NA	NA
WP_115173940.1\|309233_309356_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_004394087.1\|309434_309707_+	DUF1778 domain-containing protein	NA	NA	NA	NA
WP_078927600.1\|309703_310201_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_115173900.1\|310221_310362_-	hypothetical protein	NA	NA	NA	NA
WP_115173899.1\|310310_311144_-	hypothetical protein	NA	NA	NA	NA
WP_078927599.1\|311143_311989_-	hypothetical protein	NA	NA	NA	NA
WP_078927598.1\|312160_313135_-	FRG domain-containing protein	NA	NA	NA	NA
WP_158116599.1\|313183_314035_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	4.4e-55	42.7
WP_115173898.1\|314539_314953_-	GFA family protein	NA	NA	NA	NA
WP_115173897.1\|315459_315582_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_115173894.1\|315619_316033_-	hypothetical protein	NA	NA	NA	NA
WP_072668974.1\|317355_317466_-	DUF3265 domain-containing protein	NA	NA	NA	NA
317047:317078	attR	NA	NA	NA	NA
WP_078927644.1\|317462_317897_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_139364804.1\|317911_318007_-	hypothetical protein	NA	NA	NA	NA
WP_078927646.1\|318429_318729_-	hypothetical protein	NA	NA	NA	NA
WP_158116599.1\|319395_320247_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	4.4e-55	42.7
WP_113594551.1\|322132_322249_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_113594550.1\|322245_322548_-	hypothetical protein	NA	NA	NA	NA
WP_158142139.1\|322548_322704_-	hypothetical protein	NA	NA	NA	NA
WP_025590728.1\|322864_323284_-	hypothetical protein	NA	NA	NA	NA
WP_115173896.1\|323285_323492_-\|transposase	transposase	NA	NA	NA	NA
WP_038970004.1\|324682_325342_-	hypothetical protein	NA	NA	NA	NA
WP_078927623.1\|325477_325993_-	peptide deformylase	E3SLL2	Synechococcus_phage	6.0e-15	38.4
WP_078927624.1\|326147_326744_-	glutathione S-transferase family protein	NA	NA	NA	NA
WP_000351249.1\|326900_327302_-	type II toxin-antitoxin system death-on-curing family toxin	A0A222YZ88	Escherichia_phage	7.2e-08	29.8
WP_001080654.1\|327301_327472_-	hypothetical protein	NA	NA	NA	NA
WP_115173939.1\|327542_327668_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_078927625.1\|327649_328636_-	DUF3644 domain-containing protein	NA	NA	NA	NA
WP_158142140.1\|328701_329553_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	1.5e-55	42.7
WP_001071517.1\|331050_331410_-	VOC family protein	NA	NA	NA	NA
WP_115173938.1\|332448_332565_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_078927613.1\|332627_333026_-	aegerolysin	NA	NA	NA	NA
WP_115173937.1\|333151_333268_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_062907537.1\|333264_333702_-	helix-turn-helix domain-containing protein	A0A0P0IRJ4	Acinetobacter_phage	2.1e-21	38.3
WP_078927615.1\|333712_334054_-	DUF4258 domain-containing protein	NA	NA	NA	NA
WP_045570037.1\|335351_335567_-	hypothetical protein	NA	NA	NA	NA
WP_078927617.1\|335704_336202_-	hypothetical protein	NA	NA	NA	NA
WP_078927618.1\|336188_336902_-	hypothetical protein	C9DG53	Deftia_phage	1.0e-20	38.6
WP_158116599.1\|337073_337925_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	4.4e-55	42.7

DBSCAN-SWA_3

343054 : 399563

Shigella_phage(25.0%)

transposase,integrase,tRNA

attL 342019:342033|attR 391983:391997

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
342019:342033	attL	NA	NA	NA	NA
WP_158116599.1\|343054_343906_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	4.4e-55	42.7
WP_078927665.1\|344792_344903_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_078927664.1\|344982_345213_+	secretion protein	NA	NA	NA	NA
WP_080115560.1\|346288_346399_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_115173892.1\|346454_346745_-	hypothetical protein	NA	NA	NA	NA
WP_108315877.1\|347272_347389_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_078927658.1\|347379_347844_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_078927656.1\|347991_348744_-	SDR family oxidoreductase	F2NZ40	Diadromus_pulchellus_ascovirus	1.6e-21	32.0
WP_078927662.1\|348835_349969_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_115173883.1\|350203_351529_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	2.0e-30	31.3
WP_078927652.1\|353381_354044_-	Vat family streptogramin A O-acetyltransferase	A0A2R8FE91	Brazilian_cedratvirus	2.5e-26	39.6
WP_078927653.1\|354162_354615_-	hypothetical protein	NA	NA	NA	NA
WP_115173891.1\|355382_355898_-	hypothetical protein	NA	NA	NA	NA
WP_078927642.1\|355974_356064_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_078927640.1\|356867_357155_-	hypothetical protein	NA	NA	NA	NA
WP_078927641.1\|357400_357703_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_000861987.1\|357690_357948_-	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_001012254.1\|358213_358492_-	hypothetical protein	NA	NA	NA	NA
WP_158116599.1\|358550_359402_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	4.4e-55	42.7
WP_139364809.1\|359896_360664_-	hypothetical protein	NA	NA	NA	NA
WP_078927662.1\|360705_361839_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_115173883.1\|362073_363399_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	2.0e-30	31.3
WP_032480862.1\|364474_364753_+	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_002033296.1\|364745_365015_+	type II toxin-antitoxin system YafQ family toxin	NA	NA	NA	NA
WP_078927637.1\|365149_365857_-	hypothetical protein	NA	NA	NA	NA
WP_078927636.1\|366042_366600_+	hypothetical protein	NA	NA	NA	NA
WP_139364803.1\|366723_366912_+	hypothetical protein	NA	NA	NA	NA
WP_158116599.1\|367637_368489_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	4.4e-55	42.7
WP_078927669.1\|369472_370072_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_115173889.1\|372589_372679_-	hypothetical protein	NA	NA	NA	NA
WP_078927655.1\|372883_373306_-	hypothetical protein	NA	NA	NA	NA
WP_115173888.1\|373549_374578_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_078927661.1\|374627_375011_-	hypothetical protein	NA	NA	NA	NA
WP_078927660.1\|375157_375988_-	DUF4238 domain-containing protein	NA	NA	NA	NA
WP_158116599.1\|376037_376889_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	4.4e-55	42.7
WP_115173886.1\|377735_377912_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_078927626.1\|377908_378283_-	hypothetical protein	NA	NA	NA	NA
WP_078927627.1\|378440_379643_-	DUF3644 domain-containing protein	A0A0N9RUA4	Staphylococcus_phage	9.3e-27	27.1
WP_078927628.1\|379786_380899_-	hypothetical protein	NA	NA	NA	NA
WP_078927629.1\|381112_381295_-	DUF645 family protein	NA	NA	NA	NA
WP_078927648.1\|382633_382822_+	hypothetical protein	NA	NA	NA	NA
WP_078927649.1\|383133_383610_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_115173931.1\|384587_384698_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_000126952.1\|384754_385003_+	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_000221349.1\|384992_385283_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A2H4JBF4	uncultured_Caudovirales_phage	9.1e-21	57.4
WP_113594551.1\|385331_385448_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_113594550.1\|385444_385747_-	hypothetical protein	NA	NA	NA	NA
WP_158142139.1\|385747_385903_-	hypothetical protein	NA	NA	NA	NA
WP_115173884.1\|386448_386562_-	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_078927668.1\|386654_386897_+	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_039428516.1\|386905_387205_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_078927662.1\|387326_388460_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_115173883.1\|388694_390020_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	2.0e-30	31.3
WP_078925954.1\|390682_391645_+\|integrase	integron integrase	A0A1P8DJJ6	Virus_Rctr41k	2.0e-56	41.6
WP_040992521.1\|391691_392045_-	50S ribosomal protein L20	NA	NA	NA	NA
391983:391997	attR	NA	NA	NA	NA
WP_004727973.1\|392086_392281_-	50S ribosomal protein L35	NA	NA	NA	NA
WP_078925953.1\|392380_392932_-	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	2.4e-14	35.8
WP_078925952.1\|392935_394864_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	1.4e-128	37.6
WP_078925966.1\|395070_396969_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	8.6e-51	34.8
WP_078925951.1\|397562_399563_+	exoribonuclease II	Q0GXV6	Lactococcus_phage	2.0e-29	23.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP046815

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP046816

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection