CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP046751	Photobacterium damselae strain 9046-81 chromosome 2, complete sequence	2 crisprs	cas3,cas2,csa3,PD-DExK,RT,DEDDh,cas6f,cas7f,cas5f,WYL	0	10	0	0
NZ_CP046752	Photobacterium damselae strain 9046-81 chromosome 1, complete sequence	5 crisprs	DEDDh,csx1,cas3,WYL,RT,csa3,cas7f,cas6f,DinG	0	0	1	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046751_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046751_1

328391-329318

Orphan

I-F

Consensus_repeat	Method
CTTCACTGCCGAGTAGGCAGCTTAGAAA	PILER-CR
CTTCACTGCCGAGTAGGCAGCTTAGAAA	CRISPRCasFinder
CTTCACTGCCGAGTAGGCAGCTTAGAAA	CRT

15 spacers

The CRISPR arrays of NZ_CP046751_1

>merge|NZ_CP046751|1|328391-329318|PILER-CR,CRISPRCasFinder,CRT
CTTCACTGCCGAGTAGGCAGCTTAGAAAAATTCAAACAGCAAAAGATGAAAACGGTAAACCTTCACTGCCGAGTAGGCAGCTTAGAAAAACATTATAGGGATTAATTTAAGCAAGTCAACCTTCACTGCCGAGTAGGCAGCTTAGAAATATATGGAGACAAAACAAGCGAGTTATACATTCTTCACTGCCGAGTAGGCAGCTTAGAAAAAGAGGAAGCTGCCGCAGTAATTAGTATTGGACTTCACTGCCGAGTAGGCAGCTTAGAAAATTATATAGATGTCTTAAATTGAGTAAACAAACTTCACTGCCGAGTAGGCAGCTTAGAAAACTGGCGTTACTTATAGTTTACCTAAAATTAACTTCACTGCCGAGTAGGCAGCTTAGAAAATTTGGCTTTATCGGTAATCGGCACAATTCTGCTTCACTGCCGAGTAGGCAGCTTAGAAAAGTCGCTATAATGGGACGGGTAAACAAGGTTCCTTCACTGCCGAGTAGGCAGCTTAGAAATTGTTGGTATGGGAGCCATTATATAGAAGTCTCTTCACTGCCGAGTAGGCAGCTTAGAAATGATAGTCTTGGGATTATTCTTTAATAATACCCTTCACTGCCGAGTAGGCAGCTTAGAAACATTCTTTATCAGTTGTACACCTTATAGCTGTCTTCACTGCCGAGTAGGCAGCTTAGAAAACATACCACGGCGGTTTATAGGTTGTTAGACCCTTCACTGCCGAGTAGGCAGCTTAGAAATCCAAAATTACTCGGAGTTCATGCTATGTTTACTTCACTGCCGAGTAGGCAGCTTAGAAAACTATCAGTGGTATAACTCTGCAACTGTTGGTCTTCACTGCCGAGTAGGCAGCTTAGAAAAGAAACACTATCAATACTTTTAGTACCCGAAGCTTCACTGCCGCATAGGCAGCCATACTA

>NZ_CP046751|1|1|328391-329258|PILER-CR
CTTCACTGCCGAGTAGGCAGCTTAGAAA	AATTCAAACAGCAAAAGATGAAAACGGTAAAC
CTTCACTGCCGAGTAGGCAGCTTAGAAA	AACATTATAGGGATTAATTTAAGCAAGTCAAC
CTTCACTGCCGAGTAGGCAGCTTAGAAA	TATATGGAGACAAAACAAGCGAGTTATACATT
CTTCACTGCCGAGTAGGCAGCTTAGAAA	AAGAGGAAGCTGCCGCAGTAATTAGTATTGGA
CTTCACTGCCGAGTAGGCAGCTTAGAAA	ATTATATAGATGTCTTAAATTGAGTAAACAAA
CTTCACTGCCGAGTAGGCAGCTTAGAAA	ACTGGCGTTACTTATAGTTTACCTAAAATTAA
CTTCACTGCCGAGTAGGCAGCTTAGAAA	ATTTGGCTTTATCGGTAATCGGCACAATTCTG
CTTCACTGCCGAGTAGGCAGCTTAGAAA	AGTCGCTATAATGGGACGGGTAAACAAGGTTC
CTTCACTGCCGAGTAGGCAGCTTAGAAA	TTGTTGGTATGGGAGCCATTATATAGAAGTCT
CTTCACTGCCGAGTAGGCAGCTTAGAAA	TGATAGTCTTGGGATTATTCTTTAATAATACC
CTTCACTGCCGAGTAGGCAGCTTAGAAA	CATTCTTTATCAGTTGTACACCTTATAGCTGT
CTTCACTGCCGAGTAGGCAGCTTAGAAA	ACATACCACGGCGGTTTATAGGTTGTTAGACC
CTTCACTGCCGAGTAGGCAGCTTAGAAA	TCCAAAATTACTCGGAGTTCATGCTATGTTTA
CTTCACTGCCGAGTAGGCAGCTTAGAAA	ACTATCAGTGGTATAACTCTGCAACTGTTGGT
CTTCACTGCCGAGTAGGCAGCTTAGAAA

>NZ_CP046751|1|1|328391-329318|CRISPRCasFinder
CTTCACTGCCGAGTAGGCAGCTTAGAAA	AATTCAAACAGCAAAAGATGAAAACGGTAAAC
CTTCACTGCCGAGTAGGCAGCTTAGAAA	AACATTATAGGGATTAATTTAAGCAAGTCAAC
CTTCACTGCCGAGTAGGCAGCTTAGAAA	TATATGGAGACAAAACAAGCGAGTTATACATT
CTTCACTGCCGAGTAGGCAGCTTAGAAA	AAGAGGAAGCTGCCGCAGTAATTAGTATTGGA
CTTCACTGCCGAGTAGGCAGCTTAGAAA	ATTATATAGATGTCTTAAATTGAGTAAACAAA
CTTCACTGCCGAGTAGGCAGCTTAGAAA	ACTGGCGTTACTTATAGTTTACCTAAAATTAA
CTTCACTGCCGAGTAGGCAGCTTAGAAA	ATTTGGCTTTATCGGTAATCGGCACAATTCTG
CTTCACTGCCGAGTAGGCAGCTTAGAAA	AGTCGCTATAATGGGACGGGTAAACAAGGTTC
CTTCACTGCCGAGTAGGCAGCTTAGAAA	TTGTTGGTATGGGAGCCATTATATAGAAGTCT
CTTCACTGCCGAGTAGGCAGCTTAGAAA	TGATAGTCTTGGGATTATTCTTTAATAATACC
CTTCACTGCCGAGTAGGCAGCTTAGAAA	CATTCTTTATCAGTTGTACACCTTATAGCTGT
CTTCACTGCCGAGTAGGCAGCTTAGAAA	ACATACCACGGCGGTTTATAGGTTGTTAGACC
CTTCACTGCCGAGTAGGCAGCTTAGAAA	TCCAAAATTACTCGGAGTTCATGCTATGTTTA
CTTCACTGCCGAGTAGGCAGCTTAGAAA	ACTATCAGTGGTATAACTCTGCAACTGTTGGT
CTTCACTGCCGAGTAGGCAGCTTAGAAA	AGAAACACTATCAATACTTTTAGTACCCGAAG
CTTCACTGCCGCATAGGCAGCCATACTA

>NZ_CP046751|1|1|328391-329318|CRT
CTTCACTGCCGAGTAGGCAGCTTAGAAA	AATTCAAACAGCAAAAGATGAAAACGGTAAAC
CTTCACTGCCGAGTAGGCAGCTTAGAAA	AACATTATAGGGATTAATTTAAGCAAGTCAAC
CTTCACTGCCGAGTAGGCAGCTTAGAAA	TATATGGAGACAAAACAAGCGAGTTATACATT
CTTCACTGCCGAGTAGGCAGCTTAGAAA	AAGAGGAAGCTGCCGCAGTAATTAGTATTGGA
CTTCACTGCCGAGTAGGCAGCTTAGAAA	ATTATATAGATGTCTTAAATTGAGTAAACAAA
CTTCACTGCCGAGTAGGCAGCTTAGAAA	ACTGGCGTTACTTATAGTTTACCTAAAATTAA
CTTCACTGCCGAGTAGGCAGCTTAGAAA	ATTTGGCTTTATCGGTAATCGGCACAATTCTG
CTTCACTGCCGAGTAGGCAGCTTAGAAA	AGTCGCTATAATGGGACGGGTAAACAAGGTTC
CTTCACTGCCGAGTAGGCAGCTTAGAAA	TTGTTGGTATGGGAGCCATTATATAGAAGTCT
CTTCACTGCCGAGTAGGCAGCTTAGAAA	TGATAGTCTTGGGATTATTCTTTAATAATACC
CTTCACTGCCGAGTAGGCAGCTTAGAAA	CATTCTTTATCAGTTGTACACCTTATAGCTGT
CTTCACTGCCGAGTAGGCAGCTTAGAAA	ACATACCACGGCGGTTTATAGGTTGTTAGACC
CTTCACTGCCGAGTAGGCAGCTTAGAAA	TCCAAAATTACTCGGAGTTCATGCTATGTTTA
CTTCACTGCCGAGTAGGCAGCTTAGAAA	ACTATCAGTGGTATAACTCTGCAACTGTTGGT
CTTCACTGCCGAGTAGGCAGCTTAGAAA	AGAAACACTATCAATACTTTTAGTACCCGAAG
CTTCACTGCCGCATAGGCAGCCATACTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046751.1\|WP_044180089.1\|331324_331534_-\|YnbE-family-lipoprotein	unknown	unknown	gnl\|CDD\|379294
NZ_CP046751.1\|WP_106340692.1\|340126_340681_+\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
NZ_CP046751.1\|WP_141705671.1\|324600_325893_+\|DUF4113-domain-containing-protein	unknown	unknown	gnl\|CDD\|176454
NZ_CP046751.1\|WP_158134035.1\|335851_338551_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|223972
NZ_CP046751.1\|WP_005304966.1\|327091_327571_-\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|182339
NZ_CP046751.1\|WP_158134037.1\|339362_339950_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225805
NZ_CP046751.1\|WP_158134031.1\|331615_334906_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378703
NZ_CP046751.1\|WP_036765604.1\|338673_339183_-\|membrane-protein	unknown	unknown	gnl\|CDD\|227700
NZ_CP046751.1\|WP_158134033.1\|335157_335487_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046751.1\|WP_158134029.1\|327754_328261_+\|ClbS/DfsB-family-four-helix-bundle-protein	unknown	unknown	gnl\|CDD\|377957
NZ_CP046751.1\|WP_036765607.1\|329404_329818_+\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|181730
NZ_CP046751.1\|WP_036766006.1\|324201_324585_+\|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit	unknown	unknown	gnl\|CDD\|182350
NZ_CP046751.1\|WP_158134023.1\|321898_323263_+\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|240536
NZ_CP046751.1\|WP_158134027.1\|326198_326993_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225117
NZ_CP046751.1\|WP_157132372.1\|326008_326158_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046751.1\|WP_036765606.1\|330983_331307_-\|YdbL-family-protein	unknown	unknown	gnl\|CDD\|377762
NZ_CP046751.1\|WP_158134708.1\|329870_330821_-\|putative-sulfate-exporter-family-transporter	unknown	unknown	gnl\|CDD\|225411
NZ_CP046751.1\|WP_068969369.1\|319156_320173_+\|UDP-glucose-4-epimerase-GalE	unknown	unknown	gnl\|CDD\|177883
NZ_CP046751.1\|WP_158134025.1\|323353_323896_-\|SPOR-domain-containing-protein	unknown	unknown	gnl\|CDD\|225805
NZ_CP046751.1\|WP_036765612.1\|320395_321742_+\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|223587

Protein	Function_ID	Function_description	E-value
NZ_CP046751.1\|WP_044180089.1\|331324_331534_-\|YnbE-family-lipoprotein	gnl\|CDD\|379294	pfam13617, Lipoprotein_19, YnbE-like lipoprotein. This family includes lipoproteins similar to E. coli YnbE. Protein in this family are typically 60 amino acids in length and contain an N-terminal lipid attachment site, which has been included in the alignment to increase sensitivity. The specific function of these proteins is unknown.	2.21493e-11
NZ_CP046751.1\|WP_106340692.1\|340126_340681_+\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	4.21555e-77
NZ_CP046751.1\|WP_141705671.1\|324600_325893_+\|DUF4113-domain-containing-protein	gnl\|CDD\|176454	cd01700, PolY_Pol_V_umuC, umuC subunit of DNA Polymerase V. umuC subunit of Pol V. Pol V is a bacterial translesion synthesis (TLS) polymerase that consists of the heterotrimer of one umuC and two umuD subunits. Translesion synthesis is a process that allows the bypass of a variety of DNA lesions. TLS polymerases lack proofreading activity and have low fidelity and low processivity. They use damaged DNA as templates and insert nucleotides opposite the lesions. Pol V, RecA, single stranded DNA-binding protein, beta sliding clamp, and gamma clamp loading complex are responsible for inducing the SOS response in bacteria to repair UV-induced DNA damage.	3.60377e-154
NZ_CP046751.1\|WP_005304966.1\|327091_327571_-\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|182339	PRK10257, PRK10257, putative kinase inhibitor protein; Provisional.	6.61408e-64
NZ_CP046751.1\|WP_158134037.1\|339362_339950_+\|hypothetical-protein	gnl\|CDD\|225805	COG3266, DamX, Uncharacterized protein conserved in bacteria [Function unknown].	1.71621e-12
NZ_CP046751.1\|WP_158134031.1\|331615_334906_-\|hypothetical-protein	gnl\|CDD\|378703	pfam11739, DctA-YdbH, Dicarboxylate transport. In certain bacterial families this protein is expressed from the ydbH gene, and there is a suggestion that this is a form of DctA or dicarboxylate transport protein. Dicarboxylate transport proteins are found in aerobic bacteria which grow on succinate or other C4-dicarboxylates.	2.66856e-40
NZ_CP046751.1\|WP_036765604.1\|338673_339183_-\|membrane-protein	gnl\|CDD\|227700	COG5413, COG5413, Uncharacterized integral membrane protein [Function unknown].	5.26985e-31
NZ_CP046751.1\|WP_158134029.1\|327754_328261_+\|ClbS/DfsB-family-four-helix-bundle-protein	gnl\|CDD\|377957	pfam08020, DUF1706, Protein of unknown function (DUF1706). This family contains many hypothetical proteins from bacteria and yeast.	1.94533e-64
NZ_CP046751.1\|WP_036765607.1\|329404_329818_+\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|181730	PRK09256, PRK09256, aminoacyl-tRNA hydrolase.	1.20033e-71
NZ_CP046751.1\|WP_036766006.1\|324201_324585_+\|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit	gnl\|CDD\|182350	PRK10276, PRK10276, translesion error-prone DNA polymerase V autoproteolytic subunit.	1.44356e-31
NZ_CP046751.1\|WP_158134708.1\|329870_330821_-\|putative-sulfate-exporter-family-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	2.49221e-52
NZ_CP046751.1\|WP_158134027.1\|326198_326993_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	4.56274e-20
NZ_CP046751.1\|WP_068969369.1\|319156_320173_+\|UDP-glucose-4-epimerase-GalE	gnl\|CDD\|177883	PLN02240, PLN02240, UDP-glucose 4-epimerase.	0
NZ_CP046751.1\|WP_036765606.1\|330983_331307_-\|YdbL-family-protein	gnl\|CDD\|377762	pfam07027, DUF1318, Protein of unknown function (DUF1318). This family consists of several bacterial proteins of around 100 residues in length and is often known as YdbL. The function of this family is unknown.	2.05577e-32
NZ_CP046751.1\|WP_158134023.1\|321898_323263_+\|MATE-family-efflux-transporter	gnl\|CDD\|240536	cd13131, MATE_NorM_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Vibrio cholerae NorM and functions most likely as a multidrug efflux pump, removing xenobiotics from the interior of the cell. The pump utilizes a cation gradient across the membrane to facilitate the export process. NorM appears to bind monovalent cations in an outward-facing conformation and may subsequently cycle through an inward-facing and outward-facing conformation to capture and release its substrate.	2.72236e-87
NZ_CP046751.1\|WP_158134035.1\|335851_338551_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|223972	COG1042, COG1042, Acyl-CoA synthetase (NDP forming) [Energy production and conversion].	0
NZ_CP046751.1\|WP_158134025.1\|323353_323896_-\|SPOR-domain-containing-protein	gnl\|CDD\|225805	COG3266, DamX, Uncharacterized protein conserved in bacteria [Function unknown].	9.27459e-21
NZ_CP046751.1\|WP_036765612.1\|320395_321742_+\|DEAD/DEAH-box-helicase	gnl\|CDD\|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	3.10777e-132

>NZ_CP046751.1|WP_158134029.1|327754_328261_+|ClbS/DfsB-family-four-helix-bundle-protein
MSSIPTTKEELEKAINDSFSKLLIDLKVIPESESRRCEIEGNSKGCFISVCDSVAYLIGWQKLVLKWYYRKTQNLAVDFPETGYKWNQLGLLAQSFYVEYRDWTYSELLSEFESNMEQILVIVASLSNHQLYQEPWYEKWTLGRMIQFNTSSPMKNVRTKVRRFKRGM
>NZ_CP046751.1|WP_005304966.1|327091_327571_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MSNFTLTSNDIFEGQLKDKQFAFNGFGHDGDNISPQLAWENAPEGTKSFAVTCFDPDAPTGCGFWHWQVINIPAETTELEQGASGKLAAGLEMRNDYGFNGFGGACPPEGHGMHRYQFTVWALPVEKLDVPDDASCALVSFMLHGMSLAKSTITTTYVR
>NZ_CP046751.1|WP_158134027.1|326198_326993_-|helix-turn-helix-domain-containing-protein
MATSAIVITQYQGQQAQNLRNVPILLPSIVAVEQGEKQFQWHGRWIRFHKKNWLLIPAHSRITFVNNPHQTQFRSTQISFLIPPTAEMIQLSQQNADTVSNHLDSPEFIVDDEGRYLWQLLLSMPKELSQAIQQQLVNGLYQYFAEKGQLHLLYAPQEISWTEKLTQFFSQDPSQNYTIEQVCQQFGLSKATLMRRLNDESTQFREVLAQVRMGHALSLLQEKSQTVLELAQQCGYQSEVRFTQRFQKQFGLSPKQYQKTLHPM
>NZ_CP046751.1|WP_157132372.1|326008_326158_+|hypothetical-protein
MEKSKDSRKLLIISALLLVTVSLFVKGLTGALLDLIAFTLILFAVYRLR
>NZ_CP046751.1|WP_141705671.1|324600_325893_+|DUF4113-domain-containing-protein
MITRSKEVWALVDAKNFYCSCEQLFDPSLVGKPLVVLSNNDGCCVAISQQAKALGIVRGAPWFKIQREAIQQGVQVRSSNYTLYADMSRRFIEELSRFSPHVEQYSIDEAFIRLDGFQLNELADYGREIRTTILKNIGLPVRVGIGATPTLAKLGNHAAKVYEKQVRGVIQIDTEHRRQWLLERTPIQDIWGIGAKTATRLRTAGIQNGWQLAQQDSIDIRRLWNVTLARTVLELQQISCISPGDVEEKRKQILSSRTFGQGINQLDELNAALAFHCQRAGEKLRKQQSQTGVVGVFLRTNKHKNLPQHHRSAVMPLISATQDTYRILEVAQALLNEIYRGGYEYYKVGVILEQLTDVTDDAIQLDMFDSSALYESKRRELMAVADRVNARYKNGIKPASIISSTNWHMRQAHRSNRWTTRLDELPIARC
>NZ_CP046751.1|WP_036766006.1|324201_324585_+|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit
MLKVILYTESVSCGFPSPAEGHQETLELEDYLIRHPNATFFLRACGESMVGAGIYDGDLLVVDRAEEIKPGRIVIARIYDEFTCKRLVRYDESWWLQPENPTLQAFPMPEDSEIFGVVTRNIHNLLN
>NZ_CP046751.1|WP_158134025.1|323353_323896_-|SPOR-domain-containing-protein
MKLLSRKTVPALLASILLAGCSSADNPCDTGYLMPSKINGDNFQCQQPETTAPETDYNDQTTDNTVTEEPAITEDNSVSSDEAYGSFDPSHYTVQVLALKRESDLHNYISLLPTNEPVWVNWNRVEGQSWFVVIMGDYPSREAARQAIGYLPSQVQAQGPFIRSFANVQADKETNVVRMR
>NZ_CP046751.1|WP_158134023.1|321898_323263_+|MATE-family-efflux-transporter
MKTLIKLAVPLIISQLIAQMLIFTDVWMMAKLSIVAIAGGGLGAAVYSFVFIIASSTVGCVANLIAIAYGKQLRQPEKGEHDVRLALKGGILLAVLLTLSLQPLFYLMKGWLLKAGQDPEAVDLAITYLHAMKWSMLPTLILLVLRSLVSAFSETRSIMVMSLITVILNVPLSYLLAFTLKMGIAGLGYGTSLAAFIVMIGYGYWVFSRPKYRRYMPFRDFHEYRLGIMKPLMVLGIPIMIATMLEHALFSGAALLAGTLGAVSLAIHQIAMQCLNFSWNLAFGLSQAASILVSQHFGKDEPDMVRQYAKLGLGLVTATSAVIGILLSIWPEFLTHVFSIEGDALAEQLVAQLPGVMIMVALCFVVDAWQLSAISILRGMKVVVGPTISTVIGYWFVGLPAAYFLMKWAGLEGIWGGLAIGLAATGVMLVVLLFKNLSAFDKSVAEKAIVAEKA
>NZ_CP046751.1|WP_036765612.1|320395_321742_+|DEAD/DEAH-box-helicase
MHFKDLGLDPRLLKKLSHLAFDQATEIQRTAIPVAILGKDILASSKTGSGKTLAFLLPAMQRMYRSKPFTRRDPRVLILTPTRELAKQVFAQLKPLNAGTPYDAALIVGGENFNDQVKALRKDPMFVVATPGRLADHLEHRSTYLDGLEMLILDEADRMLDLGFEKELRRIHEAASHRRRQTLMFSATLDHPEVVEMAHEMLNAPKRISIGHSAEEHKDITQRFILCDNLTHKEALLNKILETEDYNQMIIFTATRADTDRLTKELNDRKLKAVALSGNLNQTQRNSIMSQFERFCHKILVTTDIASRGLDISNVSHVINFDLPKHAEEYVHRVGRTGRAGNKGDAISFVGPKDWKSFKNIEAFLQQSIEFTAIDGLKAKFKGFKIEQKKKFNKKPTEQNNQKKKTQAAKPKRHIDKRFYDNQAVGHEVFMPKKKPRNVAAEIDKDQE
>NZ_CP046751.1|WP_068969369.1|319156_320173_+|UDP-glucose-4-epimerase-GalE
MRVLVTGGMGYIGSHTCVQMIEAGMTPIILDNLYNSKETVLERVENLTGVRPAFYKGDIRDRAFLDSVFAENEIDAVIHFAGLKAVGESVEKPLEYYDNNVHGTLVLVEAMRAAGVKSLIFSSSATVYGDPASVPITEDFPTSATNPYGRSKLMVEECLTDIQHAYPEMSITLLRYFNPVGSHKSGTMGEDPQGIPNNLMPFISQVAVGRREFLSVFGDDYPTVDGTGVRDYIHVVDLADGHIAALKYKGSEAGLHIYNLGTGNGNSVLQMVSAFEKASGAKVAYKIAPRRPGDIAECWADPAKAKRELHWEATHTIEDMTADTWRWQSTNPNGYPDA
>NZ_CP046751.1|WP_036765607.1|329404_329818_+|aminoacyl-tRNA-hydrolase
MLTISNNVTISDWEIELNAIRSAGNGGQNVNKVATAIHLRFDIKKSSLPAIYKEKLLKLSDSRISSDGVIIIKSQQYRTQLQNKEAALERLKELILSAMVVQKARRPTKPTKNSQRRRLESKTKRGTTKTMRKKVDY
>NZ_CP046751.1|WP_158134708.1|329870_330821_-|putative-sulfate-exporter-family-transporter
MSFKKIFSRLQPSDALFFIAALFCLLPFVSSPIALILGFSLASLGLVPTQFNIAAATKKLLSYSIIGLGFGIHLNEAIEASKQGLGLIVCSIFFTLILGWVVTRLMGLDKKTGHLIASGTAICGGSAIAAVAPAINAKDDEISLALATVFVLNAIALFIFPVIGHLLDMSQHAFGTWAAIAIHDTSSVVGAAGSYGDEALKTATTLKLARALWIIPVAFISALLFKGNSKKISVPFFIVFYCLAIVFAHFVPSLQPAYDMIFAFSKRLLVMCLFLIGSGITINKLRNAGAKPLLLGVILWLAIGGASLAYIEATMV
>NZ_CP046751.1|WP_036765606.1|330983_331307_-|YdbL-family-protein
MKRITLFLCALLFSVNAFAISLQQAKSQGLVGEANNGYIAIVTGSPSAEVKRLVQQVNQQRKSKYQSIGSSHGLSVNEVARLAYKKAVSKTPRGQYYQSTTGQWVKK
>NZ_CP046751.1|WP_044180089.1|331324_331534_-|YnbE-family-lipoprotein
MQQSVVIHKLTVLGAAVLITFALIGCTPTVQVATSDKPIEVNLNVKIEHEIRIKVDKEIDNLFKDEAVF
>NZ_CP046751.1|WP_158134031.1|331615_334906_-|hypothetical-protein
MTLDSYPKKIPASSHSSPDQATNHTSNHKKKWLRRLGFLLAALLGLSLASVYTLLKLLAQHEVQIHRISGIQLFSAPHIEKLAVVYQGVPIEMNHISINTSPLTIKIQQVQSQIPKKDQEPLQPYQFSSLQLEQLEMHSPSWRLDQMFTAKINKATVGLTINQEPAHIYQQQIHQLYIEIDPNNNGDSTNNYSNNSYAIAAKIHDIDVTVPVQTKVEDQPDVEIIQYRANLKQLSAKLQIAKNNPMQQPIPLSVAIDTIKPSWQSLEEIEQTIQNIHIDTDLTHWKSNTTIKINQAHLIQPQYLPLDIKKSDSEYQGFHIGQAIANLAQLPVNFSINQLTYLPLIYNAEVFLQQPSLDNLVTDQEQPQRPHFYFSGHVLSQQPYKMDLSLFYQDLKNMTVTAGLVGKKGNSIFCDSVISADLPLPKRLDCQLNLKQTKDITDNWQMTDAPNAILNKPITLQARQINHLIPNEVKNDDIKSAHYHVDLTLPQKINIQLPEAWSWDLLNIPRQVQVTNDGKLSIELRYAEKFLQLSLRGKQESLGVSVQNKKQHIIKTNLDINKLKCFPSKLQCHGNGVISNHLSSLLFSSLPQQIDTSSPLILQTQSHWQLTYKDQQFIGQLTDNQLSLPSFRLQQPSYSLELSNNQLAVPQWVILANNLANTHQWQWYIPKDKDITFTSNAEATVAIETNSQASHPVQKITSPLKITMGSFWVDKQSKQSIKIKSHIHSQLSPILNGQALPKLDLNTQLQLAKGEISLENRIHSLLPNQQSVPLADIKIRHNLNQQSGLLDVRLSPWQFDSKRRLSKYYLPEIPTGIELVSGKLEGHLVTRYRQFQPISSQVSLYTKELSGIFFNIPFHNANIQLELQQDQQGIQTRSPAIVDIEKIKLGIPLTNIRLSGHYQDYAYKLNHGYIELLDGFITTTPTQSRQPWQQLSLPISIHGINLAALMSQIDQQDIELTGILDGKLTLALHKGLFDIHNGKLIARYPGGLFRYKQGSTIDNQVEAMDDNNPIVVSKLLKNYHYRTLVVDIDYSNKGILKAKSQFKGYNPDFQNGRPIHLNLNIEDNVPALIKTLSLLNSSDVERYLQEQFGKQE
>NZ_CP046751.1|WP_158134033.1|335157_335487_-|hypothetical-protein
MKSAPHSLNQTIQALKSVTTQMMAAESLTGEVMSAHMIQQITAIERTELEIASQQIMVIEKALIQALVALEREDLVATREAIFNALYELNHQSPSIPKLMYENDPVLAG
>NZ_CP046751.1|WP_158134035.1|335851_338551_-|GNAT-family-N-acetyltransferase
MATTPLSALLNPKSIAVIGASNQTHRTGFVIINNLLQSHFNGPIFPVTPKYDSVAGILAYPTISDLPRTPDIAIVCTHASKTVKIIKELGEKGVKSAVILAAGTSTLKDETGTTVADYLQQLAKRYQIRLLGPNSMGIILPWLNLNASFAPTPANKGNIAFISQSAAVCTTILDWARNKNIGFSTFISLGDGLDINFAELLDALSRDGKTEAILLYLDSVNNAREFLSAARAAARNRRILVVKGGRTLAGSEAVKHHTGSNLGADIVYEAAIRRAGLLRVKNTHELFAAVETLAHSVPLRGERLAIITNGGGPAIMAVDSLSERGGKLAQFSSTTLHQLKKQLPNYWPASNPIDLLGDATIERYEHAINTLLDSDEADALLIMHTPSAIAPSQQTAERLVQTLKQHPNIKKFNVLSNWTGEYEGQVARDIFAQAGFPAYRTPESAVSAFMYLVEYRRNQKLLRETPKTLEPIATSNDNFSPQQAQAIIQELLNHQITQLETHEVQPILKGYGFKTLPTWLANDAVEAIHIAEQIGYPVAVKLRSPDIEHKSEVHGVMLHLRDAQEVESAAQAMLERVNIDYPTAQIDGLLVQRMANRAGAQELRVAVRNDPIFGPVIFLGEELMNWNCYQDSAVGLPPLNMALARYMIIDALKSQKIKQRSTLVPIDIDALCSLLVTVSQLIIDCPNIESLDIHPLLANGPELTIIDASMTLNADTNQIPRLAIRPYPKELEQWVELKSGKTILLRPILPEDEPEHKSFISHVTQEDLYKRFFSDVGEFNHEAMSNFTQIDYDREMAFIAVFENKGHTEILGVVRALSDPDNMDAEFAILIRSDLKGLGLGRIMMEKIIHYCQHKGLQRITGMTMPNNRSMIMLAQKMGFHVDIQMEDGVVEMELNLIK
>NZ_CP046751.1|WP_036765604.1|338673_339183_-|membrane-protein
MADPHIQCELDGLDKLTVLLYRSSLTFAAGVMSIIAWEFNFGTVAIIIAALLASTTVHIYDKRFRWLIQGAGLFASVWYMTGLWSPLAQGAALFVFSALAVKEYFCFQLKVLLVTPLALAGFWFCQVFGQAQISILFSMASAILLAVAAFSKWRMPLHFDIGDKSRYQI
>NZ_CP046751.1|WP_158134037.1|339362_339950_+|hypothetical-protein
MKKIAIVILASLLTGCVTSPQHSAPVQALNTPPTPEVKPQPQTVVVEPAQFSSDGLGFNEESLTGKPVEVPNHVKEVVKLSPPVTEPEVEPTTKPTYQYSELNKTAYAIQLVASGSKDQLASYAKQLPKGEALWISKTDRNGQPWYALLYGQYDSRDAAHEAIVTLPLTVQQNGAFIKNLQSLKESKNTQVSSFN
>NZ_CP046751.1|WP_106340692.1|340126_340681_+|sugar-O-acetyltransferase
MKTEFEKMISGEIYHGMDPEIDTLRTEVEKQLIPLNQTTIREQRPLLESLLGKFGSDSVIRMPFSCEYGKNIFIGDQTFVNAGAVWLDNAPITIGSHVLIGPNSQLFTPTHSLDYRSRRNWETWCLPITIEDDVWIGGNVCICQGVTIGARSVVAAGSVVTSDVPPDTLVGGTPAKVIKALNND

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP046751_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046751_2

1198265-1198412

Unclear

Consensus_repeat	Method
ATTATCAGCTACCTATTCGGCAGTTCAC	CRISPRCasFinder

2 spacers

cas6f,cas7f,cas5f,WYL

The CRISPR arrays of NZ_CP046751_2

>merge|NZ_CP046751|2|1198265-1198412|CRISPRCasFinder
AAAAAGATCTACTTATTCAGCAGTTAATTGTTCTTGAGCACGAATAAATGTGGTTCGTTTATTATCAGCTACCTATTCGGCAGTTCACTCTGAATTAACAAAGATCTCTCTAGTCATTCAATTATCAGCTACCTATTCGGCAGTTCAC

>NZ_CP046751|2|2|1198265-1198412|CRISPRCasFinder
AAAAAGATCTACTTATTCAGCAGTTAAT	TGTTCTTGAGCACGAATAAATGTGGTTCGTTT
ATTATCAGCTACCTATTCGGCAGTTCAC	TCTGAATTAACAAAGATCTCTCTAGTCATTCA
ATTATCAGCTACCTATTCGGCAGTTCAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046751.1\|WP_158134675.1\|1208055_1209468_+\|DUF262-domain-containing-protein	unknown	unknown	gnl\|CDD\|224396
NZ_CP046751.1\|WP_138222356.1\|1194788_1195274_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319968
NZ_CP046751.1\|WP_158134676.1\|1209460_1211452_+\|DUF262-domain-containing-protein	unknown	unknown	gnl\|CDD\|377008
NZ_CP046751.1\|WP_005305828.1\|1193965_1194538_-\|DUF2913-family-protein	unknown	unknown	gnl\|CDD\|371392
NZ_CP046751.1\|WP_158134671.1\|1202096_1203281_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377670
NZ_CP046751.1\|WP_158134667.1\|1199142_1200189_-\|type-I-F-CRISPR-associated-protein-Csy3	cas7f	cd09677_cas7f_CAS-I-F	gnl\|CDD\|274205
NZ_CP046751.1\|WP_036765828.1\|1191102_1192263_+\|galactokinase	unknown	unknown	gnl\|CDD\|179937
NZ_CP046751.1\|WP_158134663.1\|1197073_1198027_-\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP046751.1\|WP_158134662.1\|1196503_1196680_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046751.1\|WP_158134669.1\|1200194_1202096_-\|hypothetical-protein	cas5f	cd09736_cas5f_CAS-I-F	gnl\|CDD\|187867
NZ_CP046751.1\|WP_158134674.1\|1206714_1208055_+\|restriction-endonuclease-subunit-S	unknown	unknown	gnl\|CDD\|223804
NZ_CP046751.1\|WP_069532933.1\|1193437_1193782_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046751.1\|WP_065171326.1\|1189951_1191004_+\|UDP-glucose--hexose-1-phosphate-uridylyltransferase	unknown	unknown	gnl\|CDD\|236963
NZ_CP046751.1\|WP_158134744.1\|1203402_1204275_+\|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NZ_CP046751.1\|WP_158134661.1\|1188853_1189873_+\|UDP-glucose-4-epimerase-GalE	unknown	unknown	gnl\|CDD\|182639
NZ_CP046751.1\|WP_158134673.1\|1204328_1206710_+\|N-6-DNA-methylase	unknown	unknown	gnl\|CDD\|223363
NZ_CP046751.1\|WP_107183722.1\|1192305_1193337_+\|galactose-1-epimerase	unknown	unknown	gnl\|CDD\|182931
NZ_CP046751.1\|WP_005305843.1\|1186959_1188624_+\|BCCT-family-transporter	unknown	unknown	gnl\|CDD\|376718
NZ_CP046751.1\|WP_158134665.1\|1198540_1199140_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	cas6f	cd09674_cas6f_CAS-I-F	gnl\|CDD\|187805
NZ_CP046751.1\|WP_158134677.1\|1211479_1214560_+\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|223683

Protein	Function_ID	Function_description	E-value
NZ_CP046751.1\|WP_158134675.1\|1208055_1209468_+\|DUF262-domain-containing-protein	gnl\|CDD\|224396	COG1479, COG1479, Uncharacterized conserved protein [Function unknown].	2.47372e-33
NZ_CP046751.1\|WP_138222356.1\|1194788_1195274_-\|VOC-family-protein	gnl\|CDD\|319968	cd16361, VOC_ShValD_like, vicinal oxygen chelate (VOC) family protein similar to Streptomyces hygroscopicus ValD protein. This subfamily of vicinal oxygen chelate (VOC) family protein includes Streptomyces hygroscopicus ValD protein and similar proteins. ValD protein functions in validamycin biosynthetic pathway. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.46617e-63
NZ_CP046751.1\|WP_107183722.1\|1192305_1193337_+\|galactose-1-epimerase	gnl\|CDD\|182931	PRK11055, galM, galactose-1-epimerase; Provisional.	0
NZ_CP046751.1\|WP_158134671.1\|1202096_1203281_-\|hypothetical-protein	gnl\|CDD\|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	1.84687e-17
NZ_CP046751.1\|WP_036765828.1\|1191102_1192263_+\|galactokinase	gnl\|CDD\|179937	PRK05101, PRK05101, galactokinase; Provisional.	0
NZ_CP046751.1\|WP_158134663.1\|1197073_1198027_-\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	8.34469e-89
NZ_CP046751.1\|WP_158134669.1\|1200194_1202096_-\|hypothetical-protein	gnl\|CDD\|187867	cd09736, Csy2_I-F, CRISPR/Cas system-associated RAMP superfamily protein Csy2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; predicted Cas5 ortholog.	9.57329e-48
NZ_CP046751.1\|WP_158134674.1\|1206714_1208055_+\|restriction-endonuclease-subunit-S	gnl\|CDD\|223804	COG0732, HsdS, Restriction endonuclease S subunits [Defense mechanisms].	7.94663e-29
NZ_CP046751.1\|WP_158134676.1\|1209460_1211452_+\|DUF262-domain-containing-protein	gnl\|CDD\|377008	pfam03235, DUF262, Protein of unknown function DUF262.	7.11939e-24
NZ_CP046751.1\|WP_065171326.1\|1189951_1191004_+\|UDP-glucose--hexose-1-phosphate-uridylyltransferase	gnl\|CDD\|236963	PRK11720, PRK11720, UDP-glucose--hexose-1-phosphate uridylyltransferase.	0
NZ_CP046751.1\|WP_158134744.1\|1203402_1204275_+\|WYL-domain-containing-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	6.48435e-14
NZ_CP046751.1\|WP_158134661.1\|1188853_1189873_+\|UDP-glucose-4-epimerase-GalE	gnl\|CDD\|182639	PRK10675, PRK10675, UDP-galactose-4-epimerase; Provisional.	0
NZ_CP046751.1\|WP_158134673.1\|1204328_1206710_+\|N-6-DNA-methylase	gnl\|CDD\|223363	COG0286, HsdM, Type I restriction-modification system methyltransferase subunit [Defense mechanisms].	2.50279e-82
NZ_CP046751.1\|WP_005305828.1\|1193965_1194538_-\|DUF2913-family-protein	gnl\|CDD\|371392	pfam11140, DUF2913, Protein of unknown function (DUF2913). This family of proteins with unknown function appear to be restricted to Gammaproteobacteria.	2.24614e-21
NZ_CP046751.1\|WP_005305843.1\|1186959_1188624_+\|BCCT-family-transporter	gnl\|CDD\|376718	pfam02028, BCCT, BCCT, betaine/carnitine/choline family transporter.	0
NZ_CP046751.1\|WP_158134667.1\|1199142_1200189_-\|type-I-F-CRISPR-associated-protein-Csy3	gnl\|CDD\|274205	TIGR02566, conserved_hypothetical_protein, CRISPR type I-F/YPEST-associated protein Csy3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2463 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. This family is designated Csy3, for CRISPR/Cas Subtype Ypest protein 3.	2.07496e-96
NZ_CP046751.1\|WP_158134665.1\|1198540_1199140_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	gnl\|CDD\|187805	cd09674, Cas6_I-F, CRISPR/Cas system-associated RAMP superfamily protein Cas6f. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6f is an endoribonuclease that generates crRNA; This family is specific for CRISPR/Cas system I-F subtype; Possesses RRM fold; also known as Csy4 family.	2.58206e-38
NZ_CP046751.1\|WP_158134677.1\|1211479_1214560_+\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|223683	COG0610, COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms].	4.39834e-174

>NZ_CP046751.1|WP_158134663.1|1197073_1198027_-|IS30-family-transposase
MSYQQLTEGKRYQISALLELGISISEIANKIKCHRATIYRELKRNQSCNHYYPRYAHLSSTSRRKAASKYRIPAERIEFIRLLLCADWSPEQIANVLTKAGASVSHEWIYRYVALDKCQGGKLYRHLRQGHKRYRKGGNVKAPTIKNAISIDERALIVNSRERFGDWEIDTVLGKHGRGAIVTILERKSRFYLAKKVSSKSAEEVTKATIEMLMPYKEHVHTITADNGREFAGHQEISDALETKFYFAHPYSSWERGANENANGLLRQYVKTGTDLKTVTDEDIQFAQSRINNRPKKCLGFKQPAVIFKQMAMATWY
>NZ_CP046751.1|WP_158134662.1|1196503_1196680_+|hypothetical-protein
MMDARLERMQAMAKRFNANGSIDQLTIRRIDALVISAKRKEMAIARIKKFENRVHINQ
>NZ_CP046751.1|WP_138222356.1|1194788_1195274_-|VOC-family-protein
MKMNHVGIMVGDMDKAVEFYTKALGLNVVMGNTKVIEERETAIGRMCIAVFGEGFKGFNIAHLVTTDGIGVELFEMKERQERHEVDFSRLGIFHFCLQTDDFETAIKKIEQYGGKARMDIMRYHPEDDNKPAQMIYMEDPFGNLFELYSHTYEETYASDYE
>NZ_CP046751.1|WP_005305828.1|1193965_1194538_-|DUF2913-family-protein
MNQSQQLLDVTTNALLHLEFKKLEKTLSLAERNTLLIHFLKRIVKSNQYRGAKKPARQWLSLGRQSGADLETILVQHHESLLQTCSSDLYRFVDLIQKIEANLETKVQYSQAHRIDLNARYGRVLVCVVDEDLTSSFDEDGLMIKSTQILFIGQAADKELFSQFVEESTYFQSVVAYEDEMHLRVELFRM
>NZ_CP046751.1|WP_069532933.1|1193437_1193782_-|hypothetical-protein
MKISVDGGSFKVAIETEYEGLVGEATAIFHETLKQAKSNDKAILRFLQIIIEHRDEDDAIGYAVLGLLGWYNEAINPVTNHDIELNLPKIIPHLINPSGDLTATSATETNTFKH
>NZ_CP046751.1|WP_107183722.1|1192305_1193337_+|galactose-1-epimerase
MAQSPSFDGQPAKLVHLTNASGMTASFMDIGATWLSCTVPMPEGAREVLLRSANMDEHMKQTAYFGSIVGRFANRIAKGQFSVDGVDYQLDINNGENALHGGLVGFDKRRWAIEKQTDNQVCFALRSVDGDQGYPGNLDVMVTYTLDEENQLTILYQAHCDASCPVNLTNHAYFNLAGEGSAFNALEHSLQIKAPYYLPADATAIPTGDYKPVVGNSFDFTSLKLIGSEFLQDEDQKLAAGYDHSFVFSEEIVDGKTPVAKLVSPNHDLTMIVKTTKPAMQVYTGNYLLGSIGASKAYQNHDGVALETQYFPDSPNKEQWQQLCPLLLPEQTYHHQTCYQFEF
>NZ_CP046751.1|WP_036765828.1|1191102_1192263_+|galactokinase
MSDLIQNVTHSFNQVLGYAPTHIIQAPGRVNLIGEHTDYNDGFVLPCAINYQTMVAAAKRDDNIVRVVSVDYDNAVDEFDITQEITFQQDKMWANYIRGVVKYLLARGYQFTGADISVSGNVPQGAGLSSSAALEVVIGQTFKVLFNLEISQADIALNGQQAENQFVGCNCGIMDQMISAEGRENHAMLLDCRSLETEAVSMPEDMAVVIINSNKKRGLVDSEYNTRRQQCEEAARIFGVKALRDVTIEQFNEKVSELDELVAKRARHVITENDRTVEAAQALRAHDMKRMGELMAESHASMRDDFEITVKEIDTLVDIVKQVIGEQGGVRMTGGGFGGCIVSLVPPSLVEDVKAAVESQYEAATGLKESIYVCQAKNGAGLVDAL
>NZ_CP046751.1|WP_065171326.1|1189951_1191004_+|UDP-glucose--hexose-1-phosphate-uridylyltransferase
MSNVEFNPVDHPHRRYNPLTGQWILVSPHRAKRPWSGADEKPATEQLPSYDGKCFLCPTNERISGDVNPDYKGTYVFTNDFAALMVDSPDAPKSDNPLFQTQGVRGLSRVICFSPDHSKTLPELPVEKIRGVIDTWNDQIEELGKDYIWVQAFENKGEAMGCSQPHPHGQIWANSFLPNEIERKEHNLKAYYLENGRNLLVDYVQAELKDGSRIVVETEHWVALVPYWAAWPFETMLLPKTHIRRMSELTEEQRDDLALAIKKLTSRYDNLFQCSFPYSMGWHYAPFFEQGTNVDHWQLHALFYPPLLRSATVRKFMVGYEMLAESQRDLTAEQAAQRLRDLSDIHYKEQ
>NZ_CP046751.1|WP_158134661.1|1188853_1189873_+|UDP-glucose-4-epimerase-GalE
MEILVTGGMGYIGSHTCVQMIEAGITPIIVDNLCNAKEEVLTRIEALTGIRPIFHRGDIRDEAFLDTVFSQHRIEAVIHFAGLKAVGESVAKPLEYYDNNVTGTLVLARSMRKAGVKSIVFSSSATVYGDPDVVPITEDSPTGATTNPYGTSKHMVEQCLSDLFKAEDNWSITLLRYFNPVGAHPSGSMGEDPQGIPNNLMPFIAQVAVGRREKLAVFGNDYPTPDGTGVRDYIHVMDLADGHIAALTAVGKKAGLHIYNLGTGKGSSVLEMVEAFSQACGKAVPFEISPRRAGDIAECWASTTKAERDLGWKATRTVAEMTADTWRWQSENPQGYSPV
>NZ_CP046751.1|WP_005305843.1|1186959_1188624_+|BCCT-family-transporter
MSNDNNGGIQRPDGKVKAIDTDYQIGQDNIALKVGPFGLDIHNRVFAISGMFIILFVVFTLLFREQVEPFFSGLRNWLTSNMDWFFLSAGNIFVLVCLGLIVTPLGRVRIGGTEATPDYSYAGWLAMLFAAGMGIGLVFFGVSEPMSHFSSALGGVTVENGVRTDWAPLMGAEGNTEAAAALGMAATIYHWALHPWSVYALLALGLAIFSFNKGLPLTMRSIFYPLFGERVWGWVGHIIDILAVVATVFGLATSLGYGASQAATGLNFLFGVPMTDTTQIVLIVIITALALISVVAGLDSGVKRLSEINMGLAALLLLFVIVVGPTLAIFTGFFDNIVSYLKNLPALSVPFAREDVNYSQGWTAFYWAWWISWSPFVGMFIARVSRGRSVREFIVCVILIPSTVCVLWMTAFGGTAISQYVTTGYQAVFDADLPLKLFAMLDIMPFATITSIIGIVLVVVFFITSADSGSLVIDTIAAGGKVDAPVPQRVFWCTFEGLVAIALLLGGGLAAAQAMAVTTGLPFTFVLLVATVSLIKGLMSEPRPARKSRKTATQ
>NZ_CP046751.1|WP_158134665.1|1198540_1199140_-|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4
MSWFYKTVTFLPERCDNEVLAAKCLSILHGFNYKYDTRSIGVSFPDWCDETIGKKISFISTNRIELDLLLKHQYFTQMRKLSYFDISTTNQVPDDCEYVSFIRNQLIDKSTPAGQIRKQKRLKKRAIARQELFSMSHIQQRESIVLHHYHSIEINSRSKSSFFRLNIQMKVENSLEGSSTFSSYGLSNSENSYQPVPLI
>NZ_CP046751.1|WP_158134667.1|1199142_1200189_-|type-I-F-CRISPR-associated-protein-Csy3
MELPTNLAYERSINPSDVCFFVVWPDGTKEPLRYTSRIALGQMETASLAYDSQGNIKETATAGKLAHGNPHAGDFCSVPFGSSHIECFFSVSFSSELRKPYKCNSKEVKDTIIKLIELYEKRIGWEELVSRYLINVCNGSWLWKNTKRAYRLDVELSPWPWSEKPVLFENIRTEYREESAFKAHQQWSAIRQLVIDAFSQSDGLAIFEVKATLVLPTNSEIYPSQAFTENENKSTGSKARTFQNTQIENVRSPVIGIYKVGAAIATIDDWYPNALEPLRVSRFGAHKGDVTCYRHPSTQKDLFSIIQNADKYVEHLSASGKLSQELTNDLHYLVANLIKGGMFQHKGD
>NZ_CP046751.1|WP_158134669.1|1200194_1202096_-|hypothetical-protein
MESLKELLQSRPDDLNVELKRAFRPLTPHINIDGKELDALTVLVNLTDKTADQKDLTDRAKCKEKLRDQKWWGLCLNTIEYIQSHNLKFPDIRADGVIRASTLGSLPEHLLSSSKLPQHYWAYSHDSKYVNKSAFLTSEFCWNDSISCLAIFLQDDSHILWTKLLTLGCYKKTKKAVIKQLQNFDKEEIDVTLTGNYLTQLSLPDDEDSYISISPVASQSMQSHCYQALDNEYRYTALTRYSRSTNMGVLPMTSGGALRMFTSVPNFSSTHHHKLNSNEHWLSRESIQSLKDYLQLNRLLIPENQKQAQRKLVTDNILIMIRAWLSRQDTGIDAKTLTEHLNYDLSKVKATKRFSYIPKLTRLFHSLLKQELNSPLPHPRVDGPSSNSGLFLLLPNITVSGATALSSSVTIGIPSLTAFYGYVHAFERKLRELHAATNIESFAICIHQLHLDKRGLTKEFVKKANSTISPPSTHDDWQCNFTFSFILKFSHKLNIPNDSIIKALPKRLARGATKISIADFHRIQPFDSLTSAVKYVPIQTGKWLSLYNGHLNSFDDLIASVREKRWLTPSCVGFHLLERPVEKKDALRGYKHAFSEPIIGLINPIIFRETTDPNKILWRYKYHQNHIALQTEA
>NZ_CP046751.1|WP_158134671.1|1202096_1203281_-|hypothetical-protein
MFLQRPKPYGDESLESFFIRVANKNGYSDVHRFLEATKRFLQGIDHHGYQTFPTDIEKINPCSAKNSSSARTASLLKLAQLTFNEPTELLGLAINRTNLKYSPSTSAVIRGSEVFPRSLLRTKSIPCCPLCLQENGYASYLWHFEGYDHCHIHNVPLVNRCTCGTEYDYRVSGLKGNCSNCKEPIAIKNPEISNKAIFSVANWLAGNESKNLPDVPRSYRWGLVHWWSHINDNEFDHFSFVQFFSNWPSSFHSMIDSEIEFNLEHAIVGKKELRVKDLIGRILFSSIRLPERNLKSNIILGELLQHVETNLWDNGGLLANLRMNALEATVFLNCSLDEIASMVEQRILKPNRKTKPNMPLAVNDYLFYFGDIFCLWLAAFQTDEFNRSFYVSRW
>NZ_CP046751.1|WP_158134744.1|1203402_1204275_+|WYL-domain-containing-protein
MTHESIDKLNYAQRERLVFIDFCLEYYGAVARADLVQQFQTGLASCSRDLTLYRELAPDNAELVHQTKQYVRTDSFTPLFAHDADQALNQLMQRHGASLQGNGSQVCFDAVRLTQPKQSIVAALMRAIHNSQAIQCRYHSLSSGAGNRTIVPHAIINNGHRWHVRAFDRKTNSFRDFVCSRFTKIENSETPPKTSECSSFDDAWNTIINLEIGAHPQIKHPKAIELDYEMIQGKLKIEVRSALVGYLLTQWNVDCSENGSLNAAQYQLHLKNTDVLSGLESTELLPGFNQ
>NZ_CP046751.1|WP_158134673.1|1204328_1206710_+|N-6-DNA-methylase
MDHSVHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDTLLEPSKEAVLEEVRFQKEEMKETELDDAPLCAASSYVFYNTSKWTLQTLFNTATNNQQILLANFEDYLNGFSDNVKEIVECFNLKAQIRHMAAKDVLLDVVEKFVSPNINLTPTVKEDPDGYKLPALTNLGMGYVFEELIRKFNEENNEEAGEHFTPREVIELMTRLVFDPIKDNLPLSITVYDPACGSGGMLTETQNFVEDKYPASNRDIYLFGKEINDETYAICKSDMMIKGNNPENIRVGSTLSTDEFSSERFDFMLSNPPYGKSWASEQKHIKDGKDVIDGRFKVTLKDYWGVESEQDAIPRSSDGQLLFLMEMVTKMKSPKVSPLGSRIASVHNGSSLFTGDAGSGESNIRRFIIENDLLDAIVQLPNNLFYNTGITTYIWLLNNNKPESRQGKVQLIDASLLFRKLRKNLGNKNCEFSPEHIAEIVSTYLDYQSVERAIDEKGDSIGIAAKVFKNQDFGYHKVNIERPDRRSAQFRADLIEPLRFEKSLREVMEYLYVEHGENVYEAGFVKGIENEITKWCEENDISLNKAAKTKLLDTKNWIKQRTLVNAASQLHSKIGDEVYNDFNQFKERVDAELKSLGLKLSAPEKKAILDAVSWYDEKAEKVIKKIAKLKQDKLDDLLENYECELQDLPDFGYYPTGNHNEFVTYESSSDLRDSESVPLEQSIYQYFLDEVKPHVDEAWVNLESVKIGYEISFNKYFYRHKPLRSMDEVAKDIIALEQKAEGLIADILGISVAKVQG
>NZ_CP046751.1|WP_158134674.1|1206714_1208055_+|restriction-endonuclease-subunit-S
MSNTMIKKMPKYESYKDSCEQWIGDIPAHWEVYRLKSAVYECSNGIWGSDPNGRDEIVVLRVADFDDHKLKISDEKLTYRSIPAKERQGRLLKNGDLLIEKSGGGDKTLVGRVVLFDKQYPAVTSNFVAKMTPKEWVISGFLKYVFSALYNNGVNYLSIKQTTGIQNLDASSYLNEKFCIPQKEEQYEIAKFLDNKTTQINEAIAIKQKQIELLKERKQIIIQQAVTQGLNPNVPKKDSGVDWIGTIPEHWSVKRAKYLLDEINERSETGLEELLSVSHMTGVTPRSEKNVTMFMAEDYTGSKLCHSGDLVINIMWAWMGALGVSDRTGIVSPSYGVFREQREGTFVPKYLEMLLKSTKYVEYYNKVSTGLHSSRLRFYGHMLFDMAMGFPPYEEQTQIVDYISRECSKVDKAITVQAEQVSKLTEYKTTLINSAVTGKIKVTELA
>NZ_CP046751.1|WP_158134675.1|1208055_1209468_+|DUF262-domain-containing-protein
MAVVVASCTLDKLFSGVPILASDGKVEKDVHGMLAIPEYQRPYRWNEEQITRLLNDFKLHQQELSGKPEAEHCPFYLGSVILHQQGGKLNVIDGQQRLTTMALMSYLANKHADLKLVYESPESQQQIKHNLGWLYKHDASLADIDFTQINITLVVTDSEDEAYRFFETQNTGGVRLAGPDIIKAHHLRAVDERDKSAVNTFATRWEALGDLNPVVDILLRGRYWQYLNFRDYPLHNQTQQVRNSIVTELAEQTGKGDDIAFGRIARTYMPNGGESLAQPQVGYELRQPLNSGANTIHYLQYFEQLRQTYLLNNAAQGELAGFYEFYQKLVCKLDGCGYLKQLYDACLLLYISQHGQQSLEVAAKKLFRVVYSRRVENQKAVKEKSVPAFVKETPVLDWIAMSYTPEQCFAQLDGFKLSVDKSGFDKNSVKKRFVEKVSQYFGLDIDRQDYANQFGPTFSQHISALGAKHG
>NZ_CP046751.1|WP_158134676.1|1209460_1211452_+|DUF262-domain-containing-protein
MGDHSSVQTELLTLEKIYTDNYQFSIPSYQRPYVWSDDDVLLLFRDIKEACRLKEPNYFIGTILSSRIEQDEERIYELIDGQQRTTTLMLMTIAFKYAGIKSDLAGLAVYTSNNGEDKPRLQFSIREQVQQLLGGLAGLKNYQVPSKEMVADNAYLKQMGVALDVLTKEVEKLKSDDVVSAEAMGDYLYRQVQWVNNIVPTQMDLNRLFATMNTAGIQLEQADILKAKLFKHIHTNKAQYDAMWVACEHLENYFERNVRKVFPNADWYHIEPEHLASFDAERFAAKDETSEALPGLSIAQLASQVKASSIPDNTKQGKFETYDLDVETVYCRPIIKFPLLLIHAYRVYLALNDHQDIVPRLHSDRLLEIFEPLINDDEHSVKLFIETLWQVRYQFDRWVVKWVERDDATDAQLGLTYQSRSKSNDTYYINRTQKELTDIVLLQSVRNFTGERSAQYWLTPFLSGLIRSSIKQDSEALELLENIDNKMSLSIDTQKEASFALAEGIEPNCQSWQSQSTYFEQSLGTSFEHYWFQKLEYLIWKQMKASESSLSSEELNKFKKYRITSKNSVEHVHPQNDEYNSRLDCKTLDSFGNLVLLSPGENSSYSNQDVDKKRIDFDRKSHFDALKLREMFVVKGQGLWGKQQIGDHLEDMMAVFAQHYKHQ
>NZ_CP046751.1|WP_158134677.1|1211479_1214560_+|DEAD/DEAH-box-helicase-family-protein
MVFMVSKTNEQALEAAIEKGLAGICREELVLGEAPLNYNNELYLIGSPSDFDKQYALDTRLFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIKRHGVLRLLKKGLDVDDAFLTLMYPAPLASSSDKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNHWTGQNAAYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKKTFFLPFNKGFNLGKGNPTNPYGHKTAYLWQEVFRKESIANIIQHFVRLDGSSKKQLDKRTLFFPRYHQMDVVRRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEVPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPFIIDGIADLSDKRFAVIIDEAHSSQSGSAHDNMNRAMGKKEVEELEDAQDKILQAMRSRKMRGNASYFAFTATPKNTTLEKFGQRQADGTYAPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSIQDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVINGKKLKGKGKGMVVTQNIESAIRYYRALTRQLDKIGNPFKVAIAFSGTKEVDGIEYTEADLNGFPEGDTKDYFDVNYKRKESDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLTSVLCVQALSRLNRSAPKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDINVLHELKDEMDDTGVYEWFEVEEFNKRFFEGRDAQDLSPIIDIAAARFNHELELENESKVDFKVKAKQFVKIYGQMASIMPYEVVHWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDDSETELDPQNPNPRGAHGTETEKDPLDEIIQIFNERWFQGWSATPEEQRVKFVNIAESIRNHPDFEAKYQNNADPHTRDLAFEKMLKEIMLQRRKDELELYKLFAQDTAFKASWTQSMQRMVGM

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP046751_2	2.2\|1198353\|32\|NZ_CP046751\|CRISPRCasFinder	1198353-1198384	32	NZ_CP018299	Photobacterium damselae strain Phdp Wu-1 plasmid plas1, complete sequence	193058-193089	1	0.969
NZ_CP046751_1	1.2\|328479\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328479-328510	32	NZ_CP025693	Lactobacillus plantarum strain IRG1 plasmid pIRG103, complete sequence	1576-1607	6	0.812
NZ_CP046751_1	1.2\|328479\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328479-328510	32	NZ_CP024062	Lactobacillus plantarum strain KACC 92189 plasmid unnamed4	7795-7826	6	0.812
NZ_CP046751_1	1.2\|328479\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328479-328510	32	NZ_CP024062	Lactobacillus plantarum strain KACC 92189 plasmid unnamed4	20286-20317	6	0.812
NZ_CP046751_1	1.1\|328419\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328419-328450	32	NZ_CP018777	Staphylococcus condimenti strain StO 2014-01 plasmid pStO2014-01, complete sequence	26185-26216	7	0.781
NZ_CP046751_1	1.5\|328659\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328659-328690	32	NZ_CP010090	Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB426, complete sequence	5859-5890	7	0.781
NZ_CP046751_1	1.7\|328779\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328779-328810	32	NZ_CP040096	Pantoea sp. SO10 plasmid unnamed1, complete sequence	8133-8164	7	0.781
NZ_CP046751_1	1.9\|328899\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328899-328930	32	MK816297	Pseudomonas virus PBPA162, complete genome	42413-42444	7	0.781
NZ_CP046751_1	1.9\|328899\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328899-328930	32	MF158038	Shigella phage Sf11 SMD-2017, complete genome	10478-10509	7	0.781
NZ_CP046751_1	1.1\|328419\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328419-328450	32	NC_022551	Blattabacterium sp. (Nauphoeta cinerea) plasmid unnamed, complete sequence	1516-1547	8	0.75
NZ_CP046751_1	1.1\|328419\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328419-328450	32	NZ_CP018877	Bacillus megaterium strain JX285 plasmid 4, complete sequence	73851-73882	8	0.75
NZ_CP046751_1	1.2\|328479\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328479-328510	32	NZ_CP022991	Paraburkholderia aromaticivorans strain BN5 plasmid pBN1, complete sequence	361967-361998	8	0.75
NZ_CP046751_1	1.3\|328539\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328539-328570	32	NZ_AP017296	Nostoc sp. NIES-3756 plasmid pNOS3756_1, complete sequence	395622-395653	8	0.75
NZ_CP046751_1	1.3\|328539\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328539-328570	32	MG592671	Vibrio phage 2.275.O._10N.286.54.E11, partial genome	17055-17086	8	0.75
NZ_CP046751_1	1.8\|328839\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328839-328870	32	NZ_CP031474	Vibrio coralliilyticus strain RE22 plasmid p337, complete sequence	59909-59940	9	0.719
NZ_CP046751_1	1.8\|328839\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328839-328870	32	NZ_CP009266	Vibrio coralliilyticus strain OCN014 plasmid pOCN014, complete sequence	261742-261773	9	0.719
NZ_CP046751_1	1.1\|328419\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328419-328450	32	NC_011416	Escherichia coli SE11 plasmid pSE11-3, complete sequence	55793-55824	10	0.688
NZ_CP046751_1	1.1\|328419\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328419-328450	32	NZ_CP010201	Escherichia coli strain M10 plasmid A, complete sequence	87491-87522	10	0.688
NZ_CP046751_1	1.1\|328419\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328419-328450	32	AP014380	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S43-C70, * SEQUENCING IN PROGRESS *	30818-30849	10	0.688
NZ_CP046751_1	1.2\|328479\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328479-328510	32	KY554775	Lactococcus phage AM11, complete genome	38752-38783	10	0.688
NZ_CP046751_1	1.2\|328479\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328479-328510	32	KY554773	Lactococcus phage AM8, complete genome	38751-38782	10	0.688
NZ_CP046751_1	1.2\|328479\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328479-328510	32	KY554768	Lactococcus phage AM1, complete genome	38983-39014	10	0.688
NZ_CP046751_1	1.2\|328479\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328479-328510	32	KY554769	Lactococcus phage AM2, complete genome	38751-38782	10	0.688
NZ_CP046751_1	1.2\|328479\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328479-328510	32	KY554770	Lactococcus phage AM3, complete genome	39353-39384	10	0.688
NZ_CP046751_1	1.2\|328479\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328479-328510	32	KY554776	Lactococcus phage AM12, complete genome	38733-38764	10	0.688
NZ_CP046751_1	1.2\|328479\|32\|NZ_CP046751\|PILER-CR,CRISPRCasFinder,CRT	328479-328510	32	KY554774	Lactococcus phage AM9, complete genome	38750-38781	10	0.688
NZ_CP046751_2	2.1\|1198293\|32\|NZ_CP046751\|CRISPRCasFinder	1198293-1198324	32	NZ_CP015595	Acinetobacter sp. NCu2D-2 plasmid unnamed, complete sequence	33195-33226	10	0.688
NZ_CP046751_1	1.15\|329259\|32\|NZ_CP046751\|CRISPRCasFinder,CRT	329259-329290	32	MN047793	Xanthomonas phage Xoo-sp13, complete genome	128602-128633	11	0.656

1. spacer 2.2|1198353|32|NZ_CP046751|CRISPRCasFinder matches to NZ_CP018299 (Photobacterium damselae strain Phdp Wu-1 plasmid plas1, complete sequence) position: , mismatch: 1, identity: 0.969

tctgaattaacaaagatctctctagtcattca	CRISPR spacer
tctgaattaacaaagacctctctagtcattca	Protospacer
****************.***************

2. spacer 1.2|328479|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025693 (Lactobacillus plantarum strain IRG1 plasmid pIRG103, complete sequence) position: , mismatch: 6, identity: 0.812

aacat-tatagggattaatttaagcaagtcaac	CRISPR spacer
-atatatgtagggattaatttaatcatgtcaat	Protospacer
 *.** *.*************** ** *****.

3. spacer 1.2|328479|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024062 (Lactobacillus plantarum strain KACC 92189 plasmid unnamed4) position: , mismatch: 6, identity: 0.812

aacat-tatagggattaatttaagcaagtcaac	CRISPR spacer
-atatatgtagggattaatttaatcatgtcaat	Protospacer
 *.** *.*************** ** *****.

4. spacer 1.2|328479|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024062 (Lactobacillus plantarum strain KACC 92189 plasmid unnamed4) position: , mismatch: 6, identity: 0.812

aacat-tatagggattaatttaagcaagtcaac	CRISPR spacer
-atatatgtagggattaatttaatcatgtcaat	Protospacer
 *.** *.*************** ** *****.

5. spacer 1.1|328419|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018777 (Staphylococcus condimenti strain StO 2014-01 plasmid pStO2014-01, complete sequence) position: , mismatch: 7, identity: 0.781

--aattcaaacagcaaaagatgaaaacggtaaac	CRISPR spacer
acaagtc--acagcaaaagataaaaatggtaatg	Protospacer
  ** **  ************.****.*****

6. spacer 1.5|328659|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010090 (Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB426, complete sequence) position: , mismatch: 7, identity: 0.781

attatatagatgtcttaaattgag-taaacaaa	CRISPR spacer
tttatatagatgtctcaaatagagattaatat-	Protospacer
 **************.**** *** * **.*

7. spacer 1.7|328779|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040096 (Pantoea sp. SO10 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

atttggctttatcggtaatcggcacaattctg	CRISPR spacer
ttttggctttaccggcaatcggcaccacgcgg	Protospacer
 **********.***.********* *. * *

8. spacer 1.9|328899|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to MK816297 (Pseudomonas virus PBPA162, complete genome) position: , mismatch: 7, identity: 0.781

ttgttggtatgggagccattatatagaagtct	CRISPR spacer
tggttggtatgggagccattgtacaggcgtta	Protospacer
* ******************.**.**. **.

9. spacer 1.9|328899|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to MF158038 (Shigella phage Sf11 SMD-2017, complete genome) position: , mismatch: 7, identity: 0.781

ttgttggtatgggagccattatatagaagtct	CRISPR spacer
ttgttggtacggtagccattataataaatgct	Protospacer
*********.** **********  .**  **

10. spacer 1.1|328419|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to NC_022551 (Blattabacterium sp. (Nauphoeta cinerea) plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

aattcaaacagcaaaagatgaaaacggtaaac	CRISPR spacer
aagtaaaacagcaaaagatgaaaacaattgta	Protospacer
** * ********************..* .

11. spacer 1.1|328419|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018877 (Bacillus megaterium strain JX285 plasmid 4, complete sequence) position: , mismatch: 8, identity: 0.75

aattcaaacagcaaaagatgaaaacggtaaac--	CRISPR spacer
tattcaaagagcaaaagataaaaa--ataattag	Protospacer
 ******* **********.****  .*** .

12. spacer 1.2|328479|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022991 (Paraburkholderia aromaticivorans strain BN5 plasmid pBN1, complete sequence) position: , mismatch: 8, identity: 0.75

aacattatagggattaatttaagcaagtcaac	CRISPR spacer
tcaaatttagggattaatttaaccacgtcaag	Protospacer
   * * *************** ** *****

13. spacer 1.3|328539|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP017296 (Nostoc sp. NIES-3756 plasmid pNOS3756_1, complete sequence) position: , mismatch: 8, identity: 0.75

tatatggagacaaaacaagcgagttatacatt---	CRISPR spacer
cgtatgatgacaaaacaagcgagtt---tattaaa	Protospacer
..****. *****************   .***

14. spacer 1.3|328539|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to MG592671 (Vibrio phage 2.275.O._10N.286.54.E11, partial genome) position: , mismatch: 8, identity: 0.75

tatatggagacaaaacaagcgagttatacatt	CRISPR spacer
gtaatggagacaaaacatgcgaattacagaat	Protospacer
   ************** ****.***.* * *

15. spacer 1.8|328839|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031474 (Vibrio coralliilyticus strain RE22 plasmid p337, complete sequence) position: , mismatch: 9, identity: 0.719

agtcgctataatgggacgggtaaacaaggttc	CRISPR spacer
aaatgtgatcataggacgggtaaacaaggtca	Protospacer
*. .*. ** **.*****************.

16. spacer 1.8|328839|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009266 (Vibrio coralliilyticus strain OCN014 plasmid pOCN014, complete sequence) position: , mismatch: 9, identity: 0.719

agtcgctataatgggacgggtaaacaaggttc	CRISPR spacer
aaatgtgatcataggacgggtaaacaaggtca	Protospacer
*. .*. ** **.*****************.

17. spacer 1.1|328419|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to NC_011416 (Escherichia coli SE11 plasmid pSE11-3, complete sequence) position: , mismatch: 10, identity: 0.688

aattcaaacagcaaaagatgaaaacggtaaac	CRISPR spacer
gttatcaaaaacaaaagatgaaaacggtatta	Protospacer
. * . ** *.******************

18. spacer 1.1|328419|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010201 (Escherichia coli strain M10 plasmid A, complete sequence) position: , mismatch: 10, identity: 0.688

aattcaaacagcaaaagatgaaaacggtaaac	CRISPR spacer
gttatcaaaaacaaaagatgaaaacggtatta	Protospacer
. * . ** *.******************

19. spacer 1.1|328419|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to AP014380 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S43-C70, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 10, identity: 0.688

aattcaaacagcaaaagatgaaaacggtaaac	CRISPR spacer
aatgaaaacagcaaaagatgaaagaaaagcaa	Protospacer
***  ******************. .. . *

20. spacer 1.2|328479|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to KY554775 (Lactococcus phage AM11, complete genome) position: , mismatch: 10, identity: 0.688

aacattatagggattaatttaagcaagtcaac	CRISPR spacer
tccataatagggattaatttaatcattggatt	Protospacer
  *** **************** **    * .

21. spacer 1.2|328479|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to KY554773 (Lactococcus phage AM8, complete genome) position: , mismatch: 10, identity: 0.688

aacattatagggattaatttaagcaagtcaac	CRISPR spacer
tccataatagggattaatttaatcattggatt	Protospacer
  *** **************** **    * .

22. spacer 1.2|328479|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to KY554768 (Lactococcus phage AM1, complete genome) position: , mismatch: 10, identity: 0.688

aacattatagggattaatttaagcaagtcaac	CRISPR spacer
tccataatagggattaatttaatcattggatt	Protospacer
  *** **************** **    * .

23. spacer 1.2|328479|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to KY554769 (Lactococcus phage AM2, complete genome) position: , mismatch: 10, identity: 0.688

aacattatagggattaatttaagcaagtcaac	CRISPR spacer
tccataatagggattaatttaatcattggatt	Protospacer
  *** **************** **    * .

24. spacer 1.2|328479|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to KY554770 (Lactococcus phage AM3, complete genome) position: , mismatch: 10, identity: 0.688

aacattatagggattaatttaagcaagtcaac	CRISPR spacer
tccataatagggattaatttaatcattggatt	Protospacer
  *** **************** **    * .

25. spacer 1.2|328479|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to KY554776 (Lactococcus phage AM12, complete genome) position: , mismatch: 10, identity: 0.688

aacattatagggattaatttaagcaagtcaac	CRISPR spacer
tccataatagggattaatttaatcattggatt	Protospacer
  *** **************** **    * .

26. spacer 1.2|328479|32|NZ_CP046751|PILER-CR,CRISPRCasFinder,CRT matches to KY554774 (Lactococcus phage AM9, complete genome) position: , mismatch: 10, identity: 0.688

aacattatagggattaatttaagcaagtcaac	CRISPR spacer
tccataatagggattaatttaatcattggatt	Protospacer
  *** **************** **    * .

27. spacer 2.1|1198293|32|NZ_CP046751|CRISPRCasFinder matches to NZ_CP015595 (Acinetobacter sp. NCu2D-2 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

tgttcttgagcacgaataaatgtggttcgttt	CRISPR spacer
ctcgcttgagcacgactaaatatggtttcgat	Protospacer
. . *********** *****.*****.   *

28. spacer 1.15|329259|32|NZ_CP046751|CRISPRCasFinder,CRT matches to MN047793 (Xanthomonas phage Xoo-sp13, complete genome) position: , mismatch: 11, identity: 0.656

agaaacactatcaatacttttagtacccgaag	CRISPR spacer
ttctacactatcaatactttgattaccaatgt	Protospacer
    **************** * **** . .

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP046752

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046752_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046752_1

633081-633178

Orphan

Consensus_repeat	Method
TTCCCCTGCTCTTCCTAAAACCTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP046752_1

>merge|NZ_CP046752|1|633081-633178|CRISPRCasFinder
TTTTCCATCTCTTCCTAAGACCTTATTTTCCCCGCTATTCCCCTGCTCTTCCTAAAACCTTTTTTTCCCCGCTCTTCCCCTGCTCTTACTAAAACCTT

>NZ_CP046752|1|1|633081-633178|CRISPRCasFinder
TTTTCCATCTCTTCCTAAGACCTT	ATTTTCCCCGCTATTCCCCTGCTCTTCCTAAAACCTTTTTTTCCCCGCTC
TTCCCCTGCTCTTACTAAAACCTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046752.1\|WP_158135102.1\|642322_643489_-\|nucleotide-sugar-dehydrogenase	unknown	unknown	gnl\|CDD\|185017
NZ_CP046752.1\|WP_158135090.1\|629891_631076_-\|DUF3410-domain-containing-protein	unknown	unknown	gnl\|CDD\|240635
NZ_CP046752.1\|WP_158135096.1\|639649_640261_+\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|119407
NZ_CP046752.1\|WP_158135080.1\|622858_623263_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371551
NZ_CP046752.1\|WP_158135084.1\|623936_624197_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371551
NZ_CP046752.1\|WP_158135094.1\|637079_637433_-\|four-helix-bundle-protein	unknown	unknown	gnl\|CDD\|183395
NZ_CP046752.1\|WP_158135106.1\|644647_645181_-\|acyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_CP046752.1\|WP_106224600.1\|631242_632409_-\|nucleotide-sugar-dehydrogenase	unknown	unknown	gnl\|CDD\|185017
NZ_CP046752.1\|WP_158135082.1\|623265_623949_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371551
NZ_CP046752.1\|WP_005298228.1\|628894_629908_-\|aspartate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|237845
NZ_CP046752.1\|WP_112162650.1\|621900_622686_-\|tRNA-pseudouridine(38-40)-synthase-TruA	unknown	unknown	gnl\|CDD\|234577
NZ_CP046752.1\|WP_158135098.1\|640360_641230_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046752.1\|WP_158135100.1\|641423_642317_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|184021
NZ_CP046752.1\|WP_158135086.1\|624193_624388_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046752.1\|WP_158135104.1\|643503_644634_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340837
NZ_CP046752.1\|WP_158136375.1\|637583_638996_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|224157
NZ_CP046752.1\|WP_158135088.1\|624668_628661_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274615
NZ_CP046752.1\|WP_005298224.1\|633322_634537_-\|beta-ketoacyl-ACP-synthase-I	unknown	unknown	gnl\|CDD\|181184
NZ_CP046752.1\|WP_158135092.1\|634726_636964_+\|FAD-dependent-5-carboxymethylaminomethyl-2-thiouridine(34)-oxidoreductase-MnmC	unknown	unknown	gnl\|CDD\|234978
NZ_CP046752.1\|WP_154140320.1\|620559_621486_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	unknown	unknown	gnl\|CDD\|235547

Protein	Function_ID	Function_description	E-value
NZ_CP046752.1\|WP_158135090.1\|629891_631076_-\|DUF3410-domain-containing-protein	gnl\|CDD\|240635	cd12158, ErythrP_dh, D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains. D-Erythronate-4-phosphate Dehydrogenase (E. coli gene PdxB), a D-specific 2-hydroxyacid dehydrogenase family member, catalyzes the NAD-dependent oxidation of erythronate-4-phosphate, which is followed by transamination to form 4-hydroxy-L-threonine-4-phosphate within the de novo biosynthesis pathway of vitamin B6. D-Erythronate-4-phosphate dehydrogenase has the common architecture shared with D-isomer specific 2-hydroxyacid dehydrogenases but contains an additional C-terminal dimerization domain in addition to an NAD-binding domain and the "lid" domain. The lid domain corresponds to the catalytic domain of phosphoglycerate dehydrogenase and other proteins of the D-isomer specific 2-hydroxyacid dehydrogenase family, which include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence.	1.39791e-179
NZ_CP046752.1\|WP_158135096.1\|639649_640261_+\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|119407	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.	7.72928e-30
NZ_CP046752.1\|WP_158135080.1\|622858_623263_-\|hypothetical-protein	gnl\|CDD\|371551	pfam11477, PM0188, Sialyltransferase PMO188. PMO188 is a sialyltransferase from P.multocida. It transfers sialic acid from cytidine 5'-monophosphonuraminic acid to an acceptor sugar. It has important catalytic residues such as Asp141, His311, Glu338, Ser355 and Ser356.	1.05073e-31
NZ_CP046752.1\|WP_158135084.1\|623936_624197_-\|hypothetical-protein	gnl\|CDD\|371551	pfam11477, PM0188, Sialyltransferase PMO188. PMO188 is a sialyltransferase from P.multocida. It transfers sialic acid from cytidine 5'-monophosphonuraminic acid to an acceptor sugar. It has important catalytic residues such as Asp141, His311, Glu338, Ser355 and Ser356.	0.00414452
NZ_CP046752.1\|WP_158135094.1\|637079_637433_-\|four-helix-bundle-protein	gnl\|CDD\|183395	PRK12275, PRK12275, hypothetical protein; Reviewed.	1.09786e-42
NZ_CP046752.1\|WP_106224600.1\|631242_632409_-\|nucleotide-sugar-dehydrogenase	gnl\|CDD\|185017	PRK15057, PRK15057, UDP-glucose 6-dehydrogenase; Provisional.	0
NZ_CP046752.1\|WP_158135082.1\|623265_623949_-\|hypothetical-protein	gnl\|CDD\|371551	pfam11477, PM0188, Sialyltransferase PMO188. PMO188 is a sialyltransferase from P.multocida. It transfers sialic acid from cytidine 5'-monophosphonuraminic acid to an acceptor sugar. It has important catalytic residues such as Asp141, His311, Glu338, Ser355 and Ser356.	3.79108e-22
NZ_CP046752.1\|WP_005298228.1\|628894_629908_-\|aspartate-semialdehyde-dehydrogenase	gnl\|CDD\|237845	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional.	0
NZ_CP046752.1\|WP_112162650.1\|621900_622686_-\|tRNA-pseudouridine(38-40)-synthase-TruA	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	7.02713e-149
NZ_CP046752.1\|WP_158135100.1\|641423_642317_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|184021	PRK13389, PRK13389, UTP--glucose-1-phosphate uridylyltransferase GalU.	3.18655e-179
NZ_CP046752.1\|WP_158135102.1\|642322_643489_-\|nucleotide-sugar-dehydrogenase	gnl\|CDD\|185017	PRK15057, PRK15057, UDP-glucose 6-dehydrogenase; Provisional.	0
NZ_CP046752.1\|WP_158135106.1\|644647_645181_-\|acyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.60536e-28
NZ_CP046752.1\|WP_158135104.1\|643503_644634_-\|glycosyltransferase	gnl\|CDD\|340837	cd03808, GT4_CapM-like, capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.	1.18365e-100
NZ_CP046752.1\|WP_158136375.1\|637583_638996_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|224157	COG1236, YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis].	1.66439e-96
NZ_CP046752.1\|WP_158135088.1\|624668_628661_-\|hypothetical-protein	gnl\|CDD\|274615	TIGR03505, FimV_core, FimV N-terminal domain. This region is found at, or about 200 amino acids from, the N-terminus of FimV from Pseudomonas aeruginosa, TspA of Neisseria meningitidis, and related proteins. Disruption of FimV blocks twitching motility from type IV pili; Semmler, et al. suggest a role for this family in peptidoglycan layer remodelling required by type IV fimbrial systems. Most but not all members of this protein family have a C-terminal region recognized by TIGR03504. In between is a highly variable, often repeat-filled region rich in the negatively charged amino acids Asp and Glu.	9.67947e-25
NZ_CP046752.1\|WP_005298224.1\|633322_634537_-\|beta-ketoacyl-ACP-synthase-I	gnl\|CDD\|181184	PRK07967, PRK07967, beta-ketoacyl-ACP synthase I.	0
NZ_CP046752.1\|WP_158135092.1\|634726_636964_+\|FAD-dependent-5-carboxymethylaminomethyl-2-thiouridine(34)-oxidoreductase-MnmC	gnl\|CDD\|234978	PRK01747, mnmC, bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC.	0
NZ_CP046752.1\|WP_154140320.1\|620559_621486_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	gnl\|CDD\|235547	PRK05654, PRK05654, acetyl-CoA carboxylase carboxyltransferase subunit beta.	0

>NZ_CP046752.1|WP_106224600.1|631242_632409_-|nucleotide-sugar-dehydrogenase
MKITVVGTGYVGLSNAVLLAQNHQVVALDIIQEKVDLINNKLSPIVDAEIEQYLREKPLNLVATTDSETAYDGADFVIIATPTDYDTATNYFNTGSVEAVIKDVMVKNPTATMVIKSTIPVGYTQRIKQELGCENLIFSPEFLREGRALYDNLYPSRIIVGEQSERAQVFAHLLAEGAIKDDIPMLFTNSTEAEAVKLFSNTYLAMRVAYFNELDTYAATNGLDARQIIEGVGLDPRIGNHYNNPSFGYGGYCLPKDTKQLRANYCDVPNNIIGAIVDANTTRKDFIADSIIAKQPKVVGVYRLIMKSGSDNFRASSIQGIMKRIKAKGIEVVVYEPVLKEDDFFNSKVIRDLDTFKAMSDVIVSNRMAQELADVADKVYTRDLFGAD
>NZ_CP046752.1|WP_158135090.1|629891_631076_-|DUF3410-domain-containing-protein
MKILIDENMPYAHELFSQLGEVIAKPGRSLTPADLVDIDALMIRSVTKVNRELLTQANKLKFVGTATAGDDHVDQALLAEKGITFTAAPGCNKVGVAEYVISSLMVLGQQHGFSIFDKTIGIIGAGNVGTYLAQCLDALGIRYLLNDPLKQEQGDPRQFHTVDEILAQCDVVTLHTPITRTGLYPTHHLVDSAFLAKMQNNAILINAARGPVVDNQALKQALIDSQQGEKTLTAVLDVFEQEPLVDLELLPLLAFATPHIAGYGLEGKARGTTMVFNAFCQFIGSQLYADAKELLPVAPIPYVQLSRIWDEASLFNLTQLIYDVRKDDGIFRFEMFKTGDDSSQMASAFDQMRKNYWDRREYSAITVAGEAAFAVESLAKLGFTVVEETHESGI
>NZ_CP046752.1|WP_005298228.1|628894_629908_-|aspartate-semialdehyde-dehydrogenase
MSQEFDIAILGATGAVGEAMVEVLEERQFPVRNLYLLASDRSAGKVLRFKGKSARVTDVEDFDWSQVQIALFSAGAEASERWAPIAADEGVIVIDNTSRFRYDYDVPLVIPEVNPEAIAEYRNRNIIANPNCSTIQMLVALKPIHDAYGIERINVATYQSVSGSGKKGVDELAGQTAKLLNGLPVETNAYPKQIAFNCLPHIDQFMDNGYTKEEMKMVWETQKIFCDPNIRVNPTCVRVPVFYGHAEAVHVETAQPVNIEEALQLLENAEGIELFHGAEYPTQVSDATGKDHVMVARVREDISHPCGLNMWVVADNVRKGAATNAVQIAEKLISDYI
>NZ_CP046752.1|WP_158135088.1|624668_628661_-|hypothetical-protein
MSELSQALKRILLPVALATAFGGIAPAYANTVRIVGPENEDPNAWVQHSEQMRSSSFDYVKTPNKPYTNMRRYGPTSAKETLWSIASRHRPNNSVSVYQVIGAIKHINPQAFENNNIHGLIPGSYLVMPTLAQVKREDTQLVRRVLEQDKLREPYASKNKKTATSKPSAKKTVVKKAPVKHAAPASQTRSQTKAQPKPQTKPAVNPAKSTSTTVESADHFTIPAKPTVPANKVSPSTNTATKAALATVATATVLGPMAVDAGEPITEQSSATKVNTEQSKAITSAPAQVTSSATEGDNTGANTVSSQSNTASVQRDGAIPPKPQDVSANVAASLPQDVSNPLNASDEQLTQLIESNHMLKVRLAEMQQEMASLREQVGDDDEFRNEVINFIRQQRQQEQAVPEENKTSWLNQLADNPTALIAAGLIPGGLLAGLLAFFLYRRGKKEEQEEQAEKNSQLPLIDDASSSEPNLDSEDKLDELDDLLFDDDLFADGNDKLEQSLDRDLKQSEKTGLSESELSEVKLSESKPSESETSQSDPAPEPNFFLDDFDLNDDFDVDMSSKSVSVNGEEAALGLEEMERAIDQMDSSHSDEDLAAQWERSLQQEKVDIDSNDFDLAEGLDESFEPLEPKSEQELLDQSMLDDLLVDIDSQLEEPVTSEAASDVVSNDRASLEPQLEQEPFTSPTVEDSVQKTIDELDISSEELAEESANPTSNLSAESQTIPEVETAISESSTQLLDELITDEDDLLGADLDIDLDENSVQLLDELIPDEDDEIVLEQPLDLEENSTALLDELVDDWGEKPTEAIDATVEQSQEIEPLQTQVAEEDIDDILDQFLDQELEQHTLADEDQESSSHDYLAPEAKPLTVEELERELDRQEAEEKQSLAQAIDEFPIFDEQAALDELGGREPNSHAIPETKAQSESHIEAFEFDDLPEFDEQSALNDPEAESLLDEELALSDEDQQRALDNVVRQLQEAVEASERYQQAPELLDSIDTKLSESKETPPQELTSSEEITKESISEPSMTDASSEPSAFDEHKKKDYDFAHYDPASLPEFNEDEALQASFEEQYELEQYEREKGFSTQRPPHPIQDDYVANSAQPLPSEFDHELVESAGLDMAALLTDPDLGLADAERDGLLAHVHNDTQDDDGLDSDEQALWHQVSQDPSLENEDWSQQPSLAKDDIDSVIESIEHELEPAQEKGAYKAFQQAEELTLPEAGSELISVAQDPKPHSFISIDELMKETQGDGSALAQELDAQPLKLDVGLDEFPDVLTNIAHTDVDDHSELASKLDLAKAYLEMNDKEGAIELLEEVTAKADGAVKAEAEKLLNN
>NZ_CP046752.1|WP_158135086.1|624193_624388_-|hypothetical-protein
MKKILTVLSIFILSACNSDNDSLKETVSSNSADVVETETYQLTPVDAPSSFLSHSWSKHVAHLS
>NZ_CP046752.1|WP_158135084.1|623936_624197_-|hypothetical-protein
MNESDKQAISFNFVAPELKQDEKYCFTFKGITGDHRYITNTTLTVVAPTLEVYVDHASLPSLQQLVHIIQAKDEYPSNQRFVSWGV
>NZ_CP046752.1|WP_158135082.1|623265_623949_-|hypothetical-protein
MGRVTVDANNASKLNIHTYPLKGNNTSPEMVAAIGEYAQNKNRLNIEIYTNTTHALNNLAPIIQPLYNNENIKISHISLYDDGSAEYVNLYQWKDTPNKVDALENEVTLLADYLAGTSPDAPKWMGNRYNWHKLYDTDYYFLRKDYLDVEANLHDFRNYLGPAAKQMPWDEFAKLSDSQQALFLDIVGFDKEQLQQQYSQSPLPNFIFTGTTTWAGGKRKSIMLSNK
>NZ_CP046752.1|WP_158135080.1|622858_623263_-|hypothetical-protein
MINNAINETSPYYLGEDYDLFFKGHPAGGVINDIILGSFPEMINIPAKISFEVLMMTDMLPDTVAGIASSLYFTIPADKVNFIVFTSSDTITDREEALKSPLVQVMLTLGIVKEKDVLFWADLPDCSSGVCIDK
>NZ_CP046752.1|WP_112162650.1|621900_622686_-|tRNA-pseudouridine(38-40)-synthase-TruA
MRIALGIEYDGAKYFGWQRQREVDSVQERLEKALAKIANEPVDVFCAGRTDAGVHGTGQVVHFDVNVNRKMAAWTMGVNAHLPSDIAVRWATEVSDDFHARFTATARRYRYVIYNHALRPAILSSGVSHYHGDLDEKKMHEAGQYLLGENDFTSFRAVHCQSRSPWRNLMHLNVSRQGNYVIIDIKANAFVHHMVRNITGSLIKVGRGEEKPEWIKWLLEQKDRTLAGATAKAEGLYLVDVDYPQEFNLPRVPLGPLFLAD
>NZ_CP046752.1|WP_154140320.1|620559_621486_-|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta
MSWLEKILTKSNIVTSRKASIPEGVWTKCTSCEQVLYHADLERNLEVCPKCNHHMRMKARRRLETFLDAEGQVEIAAELEPMDKLKFRDSKKYKDRLSAAQKSSGEKDALIVMKGTVHNLPIVASAFEFSFMGGSMGSVVGAKFVRAVDEAIANNCALICFSASGGARMQEALMSLMQMAKTSAALERLSAKGLPFISVLTDPTMGGVSASLAMLGDINIGEPKALIGFAGQRVIEQTVREKLPEGFQRSEFLLEHGAIDMIVDRREMRERVAGLVAKLTNQPALDSQNHQPELTAEEEAVIKADEQE
>NZ_CP046752.1|WP_005298224.1|633322_634537_-|beta-ketoacyl-ACP-synthase-I
MKRAVITGMGIISSIGNNVEEVLESLKAGKSGINFSEQFAEMKLRSQVWGDLKINPAEHIDRKQMRFMGNAAAYAFLSMEQAIADSGLTEDQVSNERTGLVAGSGGASSMNQVAAVDILREKGVKRVGPYMVPRTMSSTVSACLATPFKIRGVNYTMSSACATSAHCIGHAVELIQLGKQDVVFAGGGEELDWSLTMMFDAMGALSTKYNDDPSKASRTYDADRDGFVISGGGGMVVIEELEHALARGAKIYGEVVGYGATSDGYDMVAPSGEGAVRCMKMAMQDLDAPVDYINTHGTSTPVGDVKELGAIQELFSENCPAISATKAMTGHALGAAGVHEAIYSTLMLDNNFVAPSINIENLDEAAQGLDIVTEMREQELKTVMSNSFGFGGTNATLVIKKFEG
>NZ_CP046752.1|WP_158135092.1|634726_636964_+|FAD-dependent-5-carboxymethylaminomethyl-2-thiouridine(34)-oxidoreductase-MnmC
MSTQDTNQHPAKIENAVLDWNELGTPVSNDFDDVYFSNANGLEETRYVFLQQNGLPDRWNDFSRRRFVVAETGFGTGLNFLALWQQFKAFRAENPDAIVKELHFISFEKFPVTLDDLKKAHLSWPELSDLAQQLHAHYPPAVADCHRIILEDGLITLDLWFGDIQDCMPQVWTGDEGIVDAWFLDGFAPSKNLAMWNLDVYKGMRNLARSGCTLATFTAAGFVRRELIEAGFEMKKAKGFGHKREMLTGTIGERSAPSNTKPWYHISARAENDTAQTLNDIAIIGGGVASAATALSLVRRGQTVTLYCKDEKPAQGASGNKQGAVYPLLNGNHNALSRFFAPAFIFARQFVEQAAQNSQFDHDWCGVVQLAFGEKMGEEGNIGREGKEGKKGGEGKAGTEGKEGEDTSLLVSSDESKERQEEGIKGGEKGADMRNKQRIKLDKMLAGGFPNELICALDYQQTRKITGVETGFDGVNYPLGGWLCPKELTRALIKQAQATGLLTLHTQSEVCKLQQESDQRWQLQFSDGQSKQHACVVIANGHRFTDFEQTANIPAYSVRGQVSHIPTNEQISKLKTVLCYDGYLTPENPHSHTHCIGASYDRNSVDLTFSEQNQHDNRQRLIDCLPQAEWAKSVDVSDNQARVGVRCATRDHLPFMGNVCRYDELLTQYENLKETQASADKVPVYNNLFALIGLGSRGLSSAPLVGEIMASQICGDPLPMPLSVLEALHPGRMWVRKLVKGRKGK
>NZ_CP046752.1|WP_158135094.1|637079_637433_-|four-helix-bundle-protein
MRCKDLEIWKRSYQLSVSVNMLMKDCRDFGLKDQICRASVSIPSNISEGAERGSNRDFIRFLYFSKGSCAELYTQLMMVRDFKYADECIVLPLLEEATRVNKMIGSYIHYLKKVEQR
>NZ_CP046752.1|WP_158136375.1|637583_638996_-|MBL-fold-metallo-hydrolase
MDIIHHGAKDGVTGSCHQLQIEQDGFTSSLLIDCGLFQGRESRPNLDIEFDISTVEALLITHCHIDHIGRIPWLLAKGFTGPIFTTEASAALLPLMLEDSLKLQLGLNKKQCQKFIERIEKQIKPVPYHCWIQQRLASFDSVSIRFSPAGHILGSAFIEIKLPNRQVVVFSGDLGPTNTPLLVDPQSPYQADILVLESTYGYKSTHGVKERALHLFDIIHRSLLDGGVILIPAFSVGRTQELLFDIENIIADTIYRCGLKEPIPINWQSLPVILDSPLAQKITEQYQQFQHLWAKEAKDKVYHGRHPLSFSQCITIEDHSDHLALINRLQKSGEPAIVVAASGMCTGGRIMNYLKALLPDSRTDVIFAGYQAEGTLGRELLDGALEVSIDKKSVEVNACIHQMSGYSAHAAQQDLLAFVDGIEHKPKRIHVIHGEEAAQRALADKLMILYPEIEVVCGVDMGGDSGKEGK
>NZ_CP046752.1|WP_158135096.1|639649_640261_+|N-acetylmuramoyl-L-alanine-amidase
MKQPLFILDAGHGGIINGQYQTAGKRSPIWSDGSQLFEGEFNRAVVAGISQQLTQRNIKHHILVPEQRDIHLRDRVRRANRLAKHYLRYQCILISVHANAGGGSGFEVFTSKGKTRSDDIADHFALAFKDVFPNKPLRADLRDGDYDKDRSFYILRYTSMPAILTENFFMDNEQECKEILMTSIGREKIVKYHVKGIRRILGA
>NZ_CP046752.1|WP_158135098.1|640360_641230_+|hypothetical-protein
MNKHYIAIHGRSNKPPAHILEDSWLRAINDGRKQTNQSLINKSQFSMAYYADVFYQQPLYFDPEPYLPSLPFLPYLPDIPSNHPPIPLAVDEDHLSEMMEQNKWRLDNLFFEPLLSEFGVYRALNYLSKPLLRYWLTDVYHYFHDPAFALEIEKPLIRLLQQYRHHSITLISHSLGTVIAYNVLQKLAAQRTTQDITIDKWITLGSPLGLASVKAQLERNLQGSLAVPDNVSAWHNYSDKRDIVCIDGDLADDFARNNAGVSVQDFQIVNAYPGNPHKSYGYLRVASSE
>NZ_CP046752.1|WP_158135100.1|641423_642317_-|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKSHIKKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQFIVNECVNAGIKEIVLVTHSSKNAIENHFDTSFELEATLEARVKRQLLDEVQNICPKDVTVMHVRQGHAKGLGHAVLCAKPLVGDAPFAVVLPDVILDEYTADQSKENLAAMLQRYEETGASQIMVEPVPMSDVSKYGVVDCNGTELVAGESCPMTRMVEKPAVEDAPSNLAVVGRYVLSHKIWDKLAITPPGAGDEIQLTDAIDMLMAEETVEAFHMSGKSHDCGDKLGYLKAFVEYGMRHKDLGEDFKAYLKASN
>NZ_CP046752.1|WP_158135102.1|642322_643489_-|nucleotide-sugar-dehydrogenase
MKITIAGTGYVGLSNAMLLAQHHEVIAVDIIKEKVKLLNDKISPIVDKEIEDFLQNKELNFTATLDKELAYKDAEYVVIATPTDYDTENNYFNTSSVEAVIKDVMAINPNAVMVIKSTIPVGYTKQIKEQFGCENIIFSPEFLREGRALYDNLYPSRIIVGERSTRAEIFANLLVEGAIKQDIPVLFTDSTEAEAVKLFSNTYLAMRVAYFNELDTYAATNGLDARQIIEGVGLDPRIGNHYNNPSFGYGGYCLPKDTKQLRANYRDVPNNIIGAIVDANTTRKDFIADSIIAKNPKCVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGIEVVVHEPVLKEKEFFHSLVINDLNEFKQSCDVIVSNRMSDELSDVADKVYTRDLFGAD
>NZ_CP046752.1|WP_158135104.1|643503_644634_-|glycosyltransferase
MKNKKIAHIQLLPLLTGVQRVSLDELTRLNRNDFTPYMICQQSGPMTDECEKNNINCLYIPTLVREISPLKDFLAFWNLYRLCKKHKFDIVHTHSSKTGVIGRLAAKLAGVPMVVHTVHGYAFPAAKNKLEKNIFLAMEWLGTKCSDKVICLHDADKKIAEEKLGAKASQIMVLANGVNLSKFNPPTLLQKQDIRSELGLPVNATVVGMVGRLWEQKNPKDLLTAAIDILKTRSDVHFVFAGDGELRAELEHRTNYHGVSSNIHFLGWRNDTESVLKAFDIFVLPSLWEGMPLAILEAQATGLPCVVSNIQGNNHLVYNEKNGYLFELNNNEQLIHSILALVDKSHRRDQMGTFALNKIKQDNDIERRIIILSSHY
>NZ_CP046752.1|WP_158135106.1|644647_645181_-|acyltransferase
MFFLLKITMLLLPFLSKNEFFLKVYSKYEVESYLKKGCVIGNKTRLYRVTLSSSFKGDKFFIGDNCTLTNCILLGHDASPSLYIKDLINNNNYYLPGARSSYRNPIVIGNNVFVGYGSIILPGVKIGDNVVIAAGSVVINDIPSSGVYGGNPARFIKPLDSFLDKYRMLLKENPELF

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP046752_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046752_2

637448-637583

Orphan

Consensus_repeat	Method
TTTCCCTATCAATCCCTTCATTCCCGCTCTTCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP046752_2

>merge|NZ_CP046752|2|637448-637583|CRISPRCasFinder
TTTTTCTTTCCTTCCACTCATCCCCTATTTTCCCTATCAATCCCTTCATTCCCGCTCTTCCCCTTCTTTTCCTATCTATCCCTTACTCCCGCTCTACCCCTCTTTCCCTATCAATCCCTTCATTCCCGCTCTTCCC

>NZ_CP046752|2|2|637448-637583|CRISPRCasFinder
TTTTTCTTTCCTTCCACTCATCCCCTATTTTCCC	TATCAATCCCTTCATTCCCGCTCTTCCCCTTCTTTTCCTATCTATCCCTTACTCCCGCTCTACCCCTC
TTTCCCTATCAATCCCTTCATTCCCGCTCTTCCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046752.1\|WP_158135112.1\|647416_648430_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379716
NZ_CP046752.1\|WP_158135090.1\|629891_631076_-\|DUF3410-domain-containing-protein	unknown	unknown	gnl\|CDD\|240635
NZ_CP046752.1\|WP_158135096.1\|639649_640261_+\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|119407
NZ_CP046752.1\|WP_158135092.1\|634726_636964_+\|FAD-dependent-5-carboxymethylaminomethyl-2-thiouridine(34)-oxidoreductase-MnmC	unknown	unknown	gnl\|CDD\|234978
NZ_CP046752.1\|WP_158135084.1\|623936_624197_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371551
NZ_CP046752.1\|WP_158135094.1\|637079_637433_-\|four-helix-bundle-protein	unknown	unknown	gnl\|CDD\|183395
NZ_CP046752.1\|WP_158135106.1\|644647_645181_-\|acyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_CP046752.1\|WP_106224600.1\|631242_632409_-\|nucleotide-sugar-dehydrogenase	unknown	unknown	gnl\|CDD\|185017
NZ_CP046752.1\|WP_158135082.1\|623265_623949_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371551
NZ_CP046752.1\|WP_005298228.1\|628894_629908_-\|aspartate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|237845
NZ_CP046752.1\|WP_158135100.1\|641423_642317_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|184021
NZ_CP046752.1\|WP_158135102.1\|642322_643489_-\|nucleotide-sugar-dehydrogenase	unknown	unknown	gnl\|CDD\|185017
NZ_CP046752.1\|WP_005298224.1\|633322_634537_-\|beta-ketoacyl-ACP-synthase-I	unknown	unknown	gnl\|CDD\|181184
NZ_CP046752.1\|WP_158135104.1\|643503_644634_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340837
NZ_CP046752.1\|WP_158135108.1\|645712_646882_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340831
NZ_CP046752.1\|WP_158135088.1\|624668_628661_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274615
NZ_CP046752.1\|WP_158135086.1\|624193_624388_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046752.1\|WP_158135098.1\|640360_641230_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046752.1\|WP_158136377.1\|645182_645692_-\|serine-acetyltransferase	unknown	unknown	gnl\|CDD\|223975
NZ_CP046752.1\|WP_158135110.1\|646874_647417_-\|serine-acetyltransferase	unknown	unknown	gnl\|CDD\|223975

Protein	Function_ID	Function_description	E-value
NZ_CP046752.1\|WP_158135112.1\|647416_648430_-\|hypothetical-protein	gnl\|CDD\|379716	pfam14897, EpsG, EpsG family. This family of proteins are related to the EpsG protein from B. subtilis. These proteins are likely glycosyl transferases belonging to the membrane protein GT-C clan.	5.06922e-11
NZ_CP046752.1\|WP_158135090.1\|629891_631076_-\|DUF3410-domain-containing-protein	gnl\|CDD\|240635	cd12158, ErythrP_dh, D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains. D-Erythronate-4-phosphate Dehydrogenase (E. coli gene PdxB), a D-specific 2-hydroxyacid dehydrogenase family member, catalyzes the NAD-dependent oxidation of erythronate-4-phosphate, which is followed by transamination to form 4-hydroxy-L-threonine-4-phosphate within the de novo biosynthesis pathway of vitamin B6. D-Erythronate-4-phosphate dehydrogenase has the common architecture shared with D-isomer specific 2-hydroxyacid dehydrogenases but contains an additional C-terminal dimerization domain in addition to an NAD-binding domain and the "lid" domain. The lid domain corresponds to the catalytic domain of phosphoglycerate dehydrogenase and other proteins of the D-isomer specific 2-hydroxyacid dehydrogenase family, which include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence.	1.39791e-179
NZ_CP046752.1\|WP_158135096.1\|639649_640261_+\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|119407	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.	7.72928e-30
NZ_CP046752.1\|WP_158135092.1\|634726_636964_+\|FAD-dependent-5-carboxymethylaminomethyl-2-thiouridine(34)-oxidoreductase-MnmC	gnl\|CDD\|234978	PRK01747, mnmC, bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC.	0
NZ_CP046752.1\|WP_158135084.1\|623936_624197_-\|hypothetical-protein	gnl\|CDD\|371551	pfam11477, PM0188, Sialyltransferase PMO188. PMO188 is a sialyltransferase from P.multocida. It transfers sialic acid from cytidine 5'-monophosphonuraminic acid to an acceptor sugar. It has important catalytic residues such as Asp141, His311, Glu338, Ser355 and Ser356.	0.00414452
NZ_CP046752.1\|WP_158135094.1\|637079_637433_-\|four-helix-bundle-protein	gnl\|CDD\|183395	PRK12275, PRK12275, hypothetical protein; Reviewed.	1.09786e-42
NZ_CP046752.1\|WP_106224600.1\|631242_632409_-\|nucleotide-sugar-dehydrogenase	gnl\|CDD\|185017	PRK15057, PRK15057, UDP-glucose 6-dehydrogenase; Provisional.	0
NZ_CP046752.1\|WP_158135082.1\|623265_623949_-\|hypothetical-protein	gnl\|CDD\|371551	pfam11477, PM0188, Sialyltransferase PMO188. PMO188 is a sialyltransferase from P.multocida. It transfers sialic acid from cytidine 5'-monophosphonuraminic acid to an acceptor sugar. It has important catalytic residues such as Asp141, His311, Glu338, Ser355 and Ser356.	3.79108e-22
NZ_CP046752.1\|WP_005298228.1\|628894_629908_-\|aspartate-semialdehyde-dehydrogenase	gnl\|CDD\|237845	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional.	0
NZ_CP046752.1\|WP_158135100.1\|641423_642317_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|184021	PRK13389, PRK13389, UTP--glucose-1-phosphate uridylyltransferase GalU.	3.18655e-179
NZ_CP046752.1\|WP_158135102.1\|642322_643489_-\|nucleotide-sugar-dehydrogenase	gnl\|CDD\|185017	PRK15057, PRK15057, UDP-glucose 6-dehydrogenase; Provisional.	0
NZ_CP046752.1\|WP_158135106.1\|644647_645181_-\|acyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.60536e-28
NZ_CP046752.1\|WP_158135104.1\|643503_644634_-\|glycosyltransferase	gnl\|CDD\|340837	cd03808, GT4_CapM-like, capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.	1.18365e-100
NZ_CP046752.1\|WP_158135108.1\|645712_646882_-\|glycosyltransferase	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	9.39626e-26
NZ_CP046752.1\|WP_158135088.1\|624668_628661_-\|hypothetical-protein	gnl\|CDD\|274615	TIGR03505, FimV_core, FimV N-terminal domain. This region is found at, or about 200 amino acids from, the N-terminus of FimV from Pseudomonas aeruginosa, TspA of Neisseria meningitidis, and related proteins. Disruption of FimV blocks twitching motility from type IV pili; Semmler, et al. suggest a role for this family in peptidoglycan layer remodelling required by type IV fimbrial systems. Most but not all members of this protein family have a C-terminal region recognized by TIGR03504. In between is a highly variable, often repeat-filled region rich in the negatively charged amino acids Asp and Glu.	9.67947e-25
NZ_CP046752.1\|WP_005298224.1\|633322_634537_-\|beta-ketoacyl-ACP-synthase-I	gnl\|CDD\|181184	PRK07967, PRK07967, beta-ketoacyl-ACP synthase I.	0
NZ_CP046752.1\|WP_158136377.1\|645182_645692_-\|serine-acetyltransferase	gnl\|CDD\|223975	COG1045, CysE, Serine acetyltransferase [Amino acid transport and metabolism].	2.75419e-28
NZ_CP046752.1\|WP_158135110.1\|646874_647417_-\|serine-acetyltransferase	gnl\|CDD\|223975	COG1045, CysE, Serine acetyltransferase [Amino acid transport and metabolism].	4.09916e-39

>NZ_CP046752.1|WP_158135094.1|637079_637433_-|four-helix-bundle-protein
MRCKDLEIWKRSYQLSVSVNMLMKDCRDFGLKDQICRASVSIPSNISEGAERGSNRDFIRFLYFSKGSCAELYTQLMMVRDFKYADECIVLPLLEEATRVNKMIGSYIHYLKKVEQR
>NZ_CP046752.1|WP_158135092.1|634726_636964_+|FAD-dependent-5-carboxymethylaminomethyl-2-thiouridine(34)-oxidoreductase-MnmC
MSTQDTNQHPAKIENAVLDWNELGTPVSNDFDDVYFSNANGLEETRYVFLQQNGLPDRWNDFSRRRFVVAETGFGTGLNFLALWQQFKAFRAENPDAIVKELHFISFEKFPVTLDDLKKAHLSWPELSDLAQQLHAHYPPAVADCHRIILEDGLITLDLWFGDIQDCMPQVWTGDEGIVDAWFLDGFAPSKNLAMWNLDVYKGMRNLARSGCTLATFTAAGFVRRELIEAGFEMKKAKGFGHKREMLTGTIGERSAPSNTKPWYHISARAENDTAQTLNDIAIIGGGVASAATALSLVRRGQTVTLYCKDEKPAQGASGNKQGAVYPLLNGNHNALSRFFAPAFIFARQFVEQAAQNSQFDHDWCGVVQLAFGEKMGEEGNIGREGKEGKKGGEGKAGTEGKEGEDTSLLVSSDESKERQEEGIKGGEKGADMRNKQRIKLDKMLAGGFPNELICALDYQQTRKITGVETGFDGVNYPLGGWLCPKELTRALIKQAQATGLLTLHTQSEVCKLQQESDQRWQLQFSDGQSKQHACVVIANGHRFTDFEQTANIPAYSVRGQVSHIPTNEQISKLKTVLCYDGYLTPENPHSHTHCIGASYDRNSVDLTFSEQNQHDNRQRLIDCLPQAEWAKSVDVSDNQARVGVRCATRDHLPFMGNVCRYDELLTQYENLKETQASADKVPVYNNLFALIGLGSRGLSSAPLVGEIMASQICGDPLPMPLSVLEALHPGRMWVRKLVKGRKGK
>NZ_CP046752.1|WP_005298224.1|633322_634537_-|beta-ketoacyl-ACP-synthase-I
MKRAVITGMGIISSIGNNVEEVLESLKAGKSGINFSEQFAEMKLRSQVWGDLKINPAEHIDRKQMRFMGNAAAYAFLSMEQAIADSGLTEDQVSNERTGLVAGSGGASSMNQVAAVDILREKGVKRVGPYMVPRTMSSTVSACLATPFKIRGVNYTMSSACATSAHCIGHAVELIQLGKQDVVFAGGGEELDWSLTMMFDAMGALSTKYNDDPSKASRTYDADRDGFVISGGGGMVVIEELEHALARGAKIYGEVVGYGATSDGYDMVAPSGEGAVRCMKMAMQDLDAPVDYINTHGTSTPVGDVKELGAIQELFSENCPAISATKAMTGHALGAAGVHEAIYSTLMLDNNFVAPSINIENLDEAAQGLDIVTEMREQELKTVMSNSFGFGGTNATLVIKKFEG
>NZ_CP046752.1|WP_106224600.1|631242_632409_-|nucleotide-sugar-dehydrogenase
MKITVVGTGYVGLSNAVLLAQNHQVVALDIIQEKVDLINNKLSPIVDAEIEQYLREKPLNLVATTDSETAYDGADFVIIATPTDYDTATNYFNTGSVEAVIKDVMVKNPTATMVIKSTIPVGYTQRIKQELGCENLIFSPEFLREGRALYDNLYPSRIIVGEQSERAQVFAHLLAEGAIKDDIPMLFTNSTEAEAVKLFSNTYLAMRVAYFNELDTYAATNGLDARQIIEGVGLDPRIGNHYNNPSFGYGGYCLPKDTKQLRANYCDVPNNIIGAIVDANTTRKDFIADSIIAKQPKVVGVYRLIMKSGSDNFRASSIQGIMKRIKAKGIEVVVYEPVLKEDDFFNSKVIRDLDTFKAMSDVIVSNRMAQELADVADKVYTRDLFGAD
>NZ_CP046752.1|WP_158135090.1|629891_631076_-|DUF3410-domain-containing-protein
MKILIDENMPYAHELFSQLGEVIAKPGRSLTPADLVDIDALMIRSVTKVNRELLTQANKLKFVGTATAGDDHVDQALLAEKGITFTAAPGCNKVGVAEYVISSLMVLGQQHGFSIFDKTIGIIGAGNVGTYLAQCLDALGIRYLLNDPLKQEQGDPRQFHTVDEILAQCDVVTLHTPITRTGLYPTHHLVDSAFLAKMQNNAILINAARGPVVDNQALKQALIDSQQGEKTLTAVLDVFEQEPLVDLELLPLLAFATPHIAGYGLEGKARGTTMVFNAFCQFIGSQLYADAKELLPVAPIPYVQLSRIWDEASLFNLTQLIYDVRKDDGIFRFEMFKTGDDSSQMASAFDQMRKNYWDRREYSAITVAGEAAFAVESLAKLGFTVVEETHESGI
>NZ_CP046752.1|WP_005298228.1|628894_629908_-|aspartate-semialdehyde-dehydrogenase
MSQEFDIAILGATGAVGEAMVEVLEERQFPVRNLYLLASDRSAGKVLRFKGKSARVTDVEDFDWSQVQIALFSAGAEASERWAPIAADEGVIVIDNTSRFRYDYDVPLVIPEVNPEAIAEYRNRNIIANPNCSTIQMLVALKPIHDAYGIERINVATYQSVSGSGKKGVDELAGQTAKLLNGLPVETNAYPKQIAFNCLPHIDQFMDNGYTKEEMKMVWETQKIFCDPNIRVNPTCVRVPVFYGHAEAVHVETAQPVNIEEALQLLENAEGIELFHGAEYPTQVSDATGKDHVMVARVREDISHPCGLNMWVVADNVRKGAATNAVQIAEKLISDYI
>NZ_CP046752.1|WP_158135088.1|624668_628661_-|hypothetical-protein
MSELSQALKRILLPVALATAFGGIAPAYANTVRIVGPENEDPNAWVQHSEQMRSSSFDYVKTPNKPYTNMRRYGPTSAKETLWSIASRHRPNNSVSVYQVIGAIKHINPQAFENNNIHGLIPGSYLVMPTLAQVKREDTQLVRRVLEQDKLREPYASKNKKTATSKPSAKKTVVKKAPVKHAAPASQTRSQTKAQPKPQTKPAVNPAKSTSTTVESADHFTIPAKPTVPANKVSPSTNTATKAALATVATATVLGPMAVDAGEPITEQSSATKVNTEQSKAITSAPAQVTSSATEGDNTGANTVSSQSNTASVQRDGAIPPKPQDVSANVAASLPQDVSNPLNASDEQLTQLIESNHMLKVRLAEMQQEMASLREQVGDDDEFRNEVINFIRQQRQQEQAVPEENKTSWLNQLADNPTALIAAGLIPGGLLAGLLAFFLYRRGKKEEQEEQAEKNSQLPLIDDASSSEPNLDSEDKLDELDDLLFDDDLFADGNDKLEQSLDRDLKQSEKTGLSESELSEVKLSESKPSESETSQSDPAPEPNFFLDDFDLNDDFDVDMSSKSVSVNGEEAALGLEEMERAIDQMDSSHSDEDLAAQWERSLQQEKVDIDSNDFDLAEGLDESFEPLEPKSEQELLDQSMLDDLLVDIDSQLEEPVTSEAASDVVSNDRASLEPQLEQEPFTSPTVEDSVQKTIDELDISSEELAEESANPTSNLSAESQTIPEVETAISESSTQLLDELITDEDDLLGADLDIDLDENSVQLLDELIPDEDDEIVLEQPLDLEENSTALLDELVDDWGEKPTEAIDATVEQSQEIEPLQTQVAEEDIDDILDQFLDQELEQHTLADEDQESSSHDYLAPEAKPLTVEELERELDRQEAEEKQSLAQAIDEFPIFDEQAALDELGGREPNSHAIPETKAQSESHIEAFEFDDLPEFDEQSALNDPEAESLLDEELALSDEDQQRALDNVVRQLQEAVEASERYQQAPELLDSIDTKLSESKETPPQELTSSEEITKESISEPSMTDASSEPSAFDEHKKKDYDFAHYDPASLPEFNEDEALQASFEEQYELEQYEREKGFSTQRPPHPIQDDYVANSAQPLPSEFDHELVESAGLDMAALLTDPDLGLADAERDGLLAHVHNDTQDDDGLDSDEQALWHQVSQDPSLENEDWSQQPSLAKDDIDSVIESIEHELEPAQEKGAYKAFQQAEELTLPEAGSELISVAQDPKPHSFISIDELMKETQGDGSALAQELDAQPLKLDVGLDEFPDVLTNIAHTDVDDHSELASKLDLAKAYLEMNDKEGAIELLEEVTAKADGAVKAEAEKLLNN
>NZ_CP046752.1|WP_158135086.1|624193_624388_-|hypothetical-protein
MKKILTVLSIFILSACNSDNDSLKETVSSNSADVVETETYQLTPVDAPSSFLSHSWSKHVAHLS
>NZ_CP046752.1|WP_158135084.1|623936_624197_-|hypothetical-protein
MNESDKQAISFNFVAPELKQDEKYCFTFKGITGDHRYITNTTLTVVAPTLEVYVDHASLPSLQQLVHIIQAKDEYPSNQRFVSWGV
>NZ_CP046752.1|WP_158135082.1|623265_623949_-|hypothetical-protein
MGRVTVDANNASKLNIHTYPLKGNNTSPEMVAAIGEYAQNKNRLNIEIYTNTTHALNNLAPIIQPLYNNENIKISHISLYDDGSAEYVNLYQWKDTPNKVDALENEVTLLADYLAGTSPDAPKWMGNRYNWHKLYDTDYYFLRKDYLDVEANLHDFRNYLGPAAKQMPWDEFAKLSDSQQALFLDIVGFDKEQLQQQYSQSPLPNFIFTGTTTWAGGKRKSIMLSNK
>NZ_CP046752.1|WP_158135096.1|639649_640261_+|N-acetylmuramoyl-L-alanine-amidase
MKQPLFILDAGHGGIINGQYQTAGKRSPIWSDGSQLFEGEFNRAVVAGISQQLTQRNIKHHILVPEQRDIHLRDRVRRANRLAKHYLRYQCILISVHANAGGGSGFEVFTSKGKTRSDDIADHFALAFKDVFPNKPLRADLRDGDYDKDRSFYILRYTSMPAILTENFFMDNEQECKEILMTSIGREKIVKYHVKGIRRILGA
>NZ_CP046752.1|WP_158135098.1|640360_641230_+|hypothetical-protein
MNKHYIAIHGRSNKPPAHILEDSWLRAINDGRKQTNQSLINKSQFSMAYYADVFYQQPLYFDPEPYLPSLPFLPYLPDIPSNHPPIPLAVDEDHLSEMMEQNKWRLDNLFFEPLLSEFGVYRALNYLSKPLLRYWLTDVYHYFHDPAFALEIEKPLIRLLQQYRHHSITLISHSLGTVIAYNVLQKLAAQRTTQDITIDKWITLGSPLGLASVKAQLERNLQGSLAVPDNVSAWHNYSDKRDIVCIDGDLADDFARNNAGVSVQDFQIVNAYPGNPHKSYGYLRVASSE
>NZ_CP046752.1|WP_158135100.1|641423_642317_-|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKSHIKKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQFIVNECVNAGIKEIVLVTHSSKNAIENHFDTSFELEATLEARVKRQLLDEVQNICPKDVTVMHVRQGHAKGLGHAVLCAKPLVGDAPFAVVLPDVILDEYTADQSKENLAAMLQRYEETGASQIMVEPVPMSDVSKYGVVDCNGTELVAGESCPMTRMVEKPAVEDAPSNLAVVGRYVLSHKIWDKLAITPPGAGDEIQLTDAIDMLMAEETVEAFHMSGKSHDCGDKLGYLKAFVEYGMRHKDLGEDFKAYLKASN
>NZ_CP046752.1|WP_158135102.1|642322_643489_-|nucleotide-sugar-dehydrogenase
MKITIAGTGYVGLSNAMLLAQHHEVIAVDIIKEKVKLLNDKISPIVDKEIEDFLQNKELNFTATLDKELAYKDAEYVVIATPTDYDTENNYFNTSSVEAVIKDVMAINPNAVMVIKSTIPVGYTKQIKEQFGCENIIFSPEFLREGRALYDNLYPSRIIVGERSTRAEIFANLLVEGAIKQDIPVLFTDSTEAEAVKLFSNTYLAMRVAYFNELDTYAATNGLDARQIIEGVGLDPRIGNHYNNPSFGYGGYCLPKDTKQLRANYRDVPNNIIGAIVDANTTRKDFIADSIIAKNPKCVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGIEVVVHEPVLKEKEFFHSLVINDLNEFKQSCDVIVSNRMSDELSDVADKVYTRDLFGAD
>NZ_CP046752.1|WP_158135104.1|643503_644634_-|glycosyltransferase
MKNKKIAHIQLLPLLTGVQRVSLDELTRLNRNDFTPYMICQQSGPMTDECEKNNINCLYIPTLVREISPLKDFLAFWNLYRLCKKHKFDIVHTHSSKTGVIGRLAAKLAGVPMVVHTVHGYAFPAAKNKLEKNIFLAMEWLGTKCSDKVICLHDADKKIAEEKLGAKASQIMVLANGVNLSKFNPPTLLQKQDIRSELGLPVNATVVGMVGRLWEQKNPKDLLTAAIDILKTRSDVHFVFAGDGELRAELEHRTNYHGVSSNIHFLGWRNDTESVLKAFDIFVLPSLWEGMPLAILEAQATGLPCVVSNIQGNNHLVYNEKNGYLFELNNNEQLIHSILALVDKSHRRDQMGTFALNKIKQDNDIERRIIILSSHY
>NZ_CP046752.1|WP_158135106.1|644647_645181_-|acyltransferase
MFFLLKITMLLLPFLSKNEFFLKVYSKYEVESYLKKGCVIGNKTRLYRVTLSSSFKGDKFFIGDNCTLTNCILLGHDASPSLYIKDLINNNNYYLPGARSSYRNPIVIGNNVFVGYGSIILPGVKIGDNVVIAAGSVVINDIPSSGVYGGNPARFIKPLDSFLDKYRMLLKENPELF
>NZ_CP046752.1|WP_158136377.1|645182_645692_-|serine-acetyltransferase
MIDSIKKDMAAHKINNLLYILLPNDKANILQFQIYMRLLEFIVNFRYLMPLYLIFKFLYLKKSEQLGFSIPINTFGAGLWIVHKGTIVVSSDAKIGSNCRIHVCVNIGKNPLGNDNAPKIGDNCYIGPGAKIYGDIYISDNTIIGANSVVNKSFYQPGKLLGIPAKRYD
>NZ_CP046752.1|WP_158135108.1|645712_646882_-|glycosyltransferase
MNDKSKLFITSKFFFPNIGGVENSLKEISKSLSDEYDVYIYTTNINNVSDDSLLLSEEFDGYNIKRIDCNHKNKYIRELLFYIKMIWSLRKEAKKSINSVIIARDHFSVINAWFAGFREISYLVPGVVKYQNNKVNHGAGKSLLFLKIENIIQKISFRLSKRIFVFSKNMMKQVTDVDNKSEVKIYLCKPGVNFNRFKIATFEEKKTLRKKYNIPSDKYIILGLARFVKAKGYENLILSMKYLSDDFYLILVGSGPEYDNYNQIISDENIKNIKIFPPTSTPNEFYKLSDVFAMTSIYEPLGQTILESQVSGLPNLYHLPSKDVITAVDEIIYKEYSFPIKENNPLSISESIVNAKLSTSNILSRKMRASIKEKFSWYKLGVLLTCKEK
>NZ_CP046752.1|WP_158135110.1|646874_647417_-|serine-acetyltransferase
MVCKYIKSDYFRYSGVEDFKLFVFLKMYFCENGFKFQFWLRLCKSRNLMIRAISYLQWFRFSRKYSLYINPKTKIGYGLYLGHGLSIVINSTAEIGNNVNIGHFTTIGSNKGKAAIIGNNVYIAPNVSIVEDVTIGNNIIIGTGSIVLSNISDGCTCAGVPSRVINKISVNKFIKNMYYE
>NZ_CP046752.1|WP_158135112.1|647416_648430_-|hypothetical-protein
MIVYYIANLFLFPVGYGYKKSNSQLRLLILFLLSTVYSLFFGLRYQVGVDWKNYITAFEFYNSNQDYFSLEVGYKILNIISYNLGYDIQFIIIITTLIVFFLSFYSLYFIKINPCYYIGVVFPYFIVMGAMNYTRQGVALSFFLLALSFLFNNKRVLFVIFLLFGCTFHVSLIIFLPLLFYRMKKSYLISIFLVLAIPFILLVNFQYSMYIQADFDSKGLLLRSAFVILSSVVLFLNRRVWDNSKYSNIYYVSMLSPVFVFTVSIVSTTMADRISYYFILLSALCCFLLCQFNGIHFKKYIVPLLFICSLTVFIIWSNFSSYIPYYEFKSQVFSGIL

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP046752_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046752_3

639325-639428

Orphan

Consensus_repeat	Method
AATGGAAGCTATGGTAAGGGGAAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP046752_3

>merge|NZ_CP046752|3|639325-639428|CRISPRCasFinder
AATGGAAGCTATGGTAAGGGGAAGAGGGAAAAGAGGTGATAAAGAAAATAGGGAGTAATGGGAAGATAAGGAGGAGAAAAAAGGGAAGCTATGGTAAGGGGAAG

>NZ_CP046752|3|3|639325-639428|CRISPRCasFinder
AATGGAAGCTATGGTAAGGGGAAG	AGGGAAAAGAGGTGATAAAGAAAATAGGGAGTAATGGGAAGATAAGGAGGAGAAAA
AAGGGAAGCTATGGTAAGGGGAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046752.1\|WP_158135112.1\|647416_648430_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379716
NZ_CP046752.1\|WP_158135090.1\|629891_631076_-\|DUF3410-domain-containing-protein	unknown	unknown	gnl\|CDD\|240635
NZ_CP046752.1\|WP_158135096.1\|639649_640261_+\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|119407
NZ_CP046752.1\|WP_158135092.1\|634726_636964_+\|FAD-dependent-5-carboxymethylaminomethyl-2-thiouridine(34)-oxidoreductase-MnmC	unknown	unknown	gnl\|CDD\|234978
NZ_CP046752.1\|WP_158135084.1\|623936_624197_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371551
NZ_CP046752.1\|WP_158135094.1\|637079_637433_-\|four-helix-bundle-protein	unknown	unknown	gnl\|CDD\|183395
NZ_CP046752.1\|WP_158135106.1\|644647_645181_-\|acyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_CP046752.1\|WP_106224600.1\|631242_632409_-\|nucleotide-sugar-dehydrogenase	unknown	unknown	gnl\|CDD\|185017
NZ_CP046752.1\|WP_005298228.1\|628894_629908_-\|aspartate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|237845
NZ_CP046752.1\|WP_158135100.1\|641423_642317_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|184021
NZ_CP046752.1\|WP_158135102.1\|642322_643489_-\|nucleotide-sugar-dehydrogenase	unknown	unknown	gnl\|CDD\|185017
NZ_CP046752.1\|WP_005298224.1\|633322_634537_-\|beta-ketoacyl-ACP-synthase-I	unknown	unknown	gnl\|CDD\|181184
NZ_CP046752.1\|WP_158135104.1\|643503_644634_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340837
NZ_CP046752.1\|WP_158136375.1\|637583_638996_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|224157
NZ_CP046752.1\|WP_158135108.1\|645712_646882_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340831
NZ_CP046752.1\|WP_158135088.1\|624668_628661_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274615
NZ_CP046752.1\|WP_158135086.1\|624193_624388_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046752.1\|WP_158135098.1\|640360_641230_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046752.1\|WP_158136377.1\|645182_645692_-\|serine-acetyltransferase	unknown	unknown	gnl\|CDD\|223975
NZ_CP046752.1\|WP_158135110.1\|646874_647417_-\|serine-acetyltransferase	unknown	unknown	gnl\|CDD\|223975

Protein	Function_ID	Function_description	E-value
NZ_CP046752.1\|WP_158135112.1\|647416_648430_-\|hypothetical-protein	gnl\|CDD\|379716	pfam14897, EpsG, EpsG family. This family of proteins are related to the EpsG protein from B. subtilis. These proteins are likely glycosyl transferases belonging to the membrane protein GT-C clan.	5.06922e-11
NZ_CP046752.1\|WP_158135090.1\|629891_631076_-\|DUF3410-domain-containing-protein	gnl\|CDD\|240635	cd12158, ErythrP_dh, D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains. D-Erythronate-4-phosphate Dehydrogenase (E. coli gene PdxB), a D-specific 2-hydroxyacid dehydrogenase family member, catalyzes the NAD-dependent oxidation of erythronate-4-phosphate, which is followed by transamination to form 4-hydroxy-L-threonine-4-phosphate within the de novo biosynthesis pathway of vitamin B6. D-Erythronate-4-phosphate dehydrogenase has the common architecture shared with D-isomer specific 2-hydroxyacid dehydrogenases but contains an additional C-terminal dimerization domain in addition to an NAD-binding domain and the "lid" domain. The lid domain corresponds to the catalytic domain of phosphoglycerate dehydrogenase and other proteins of the D-isomer specific 2-hydroxyacid dehydrogenase family, which include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence.	1.39791e-179
NZ_CP046752.1\|WP_158135096.1\|639649_640261_+\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|119407	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.	7.72928e-30
NZ_CP046752.1\|WP_158135092.1\|634726_636964_+\|FAD-dependent-5-carboxymethylaminomethyl-2-thiouridine(34)-oxidoreductase-MnmC	gnl\|CDD\|234978	PRK01747, mnmC, bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC.	0
NZ_CP046752.1\|WP_158135084.1\|623936_624197_-\|hypothetical-protein	gnl\|CDD\|371551	pfam11477, PM0188, Sialyltransferase PMO188. PMO188 is a sialyltransferase from P.multocida. It transfers sialic acid from cytidine 5'-monophosphonuraminic acid to an acceptor sugar. It has important catalytic residues such as Asp141, His311, Glu338, Ser355 and Ser356.	0.00414452
NZ_CP046752.1\|WP_158135094.1\|637079_637433_-\|four-helix-bundle-protein	gnl\|CDD\|183395	PRK12275, PRK12275, hypothetical protein; Reviewed.	1.09786e-42
NZ_CP046752.1\|WP_106224600.1\|631242_632409_-\|nucleotide-sugar-dehydrogenase	gnl\|CDD\|185017	PRK15057, PRK15057, UDP-glucose 6-dehydrogenase; Provisional.	0
NZ_CP046752.1\|WP_005298228.1\|628894_629908_-\|aspartate-semialdehyde-dehydrogenase	gnl\|CDD\|237845	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional.	0
NZ_CP046752.1\|WP_158135100.1\|641423_642317_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|184021	PRK13389, PRK13389, UTP--glucose-1-phosphate uridylyltransferase GalU.	3.18655e-179
NZ_CP046752.1\|WP_158135102.1\|642322_643489_-\|nucleotide-sugar-dehydrogenase	gnl\|CDD\|185017	PRK15057, PRK15057, UDP-glucose 6-dehydrogenase; Provisional.	0
NZ_CP046752.1\|WP_158135106.1\|644647_645181_-\|acyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.60536e-28
NZ_CP046752.1\|WP_158135104.1\|643503_644634_-\|glycosyltransferase	gnl\|CDD\|340837	cd03808, GT4_CapM-like, capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.	1.18365e-100
NZ_CP046752.1\|WP_158136375.1\|637583_638996_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|224157	COG1236, YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis].	1.66439e-96
NZ_CP046752.1\|WP_158135108.1\|645712_646882_-\|glycosyltransferase	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	9.39626e-26
NZ_CP046752.1\|WP_158135088.1\|624668_628661_-\|hypothetical-protein	gnl\|CDD\|274615	TIGR03505, FimV_core, FimV N-terminal domain. This region is found at, or about 200 amino acids from, the N-terminus of FimV from Pseudomonas aeruginosa, TspA of Neisseria meningitidis, and related proteins. Disruption of FimV blocks twitching motility from type IV pili; Semmler, et al. suggest a role for this family in peptidoglycan layer remodelling required by type IV fimbrial systems. Most but not all members of this protein family have a C-terminal region recognized by TIGR03504. In between is a highly variable, often repeat-filled region rich in the negatively charged amino acids Asp and Glu.	9.67947e-25
NZ_CP046752.1\|WP_005298224.1\|633322_634537_-\|beta-ketoacyl-ACP-synthase-I	gnl\|CDD\|181184	PRK07967, PRK07967, beta-ketoacyl-ACP synthase I.	0
NZ_CP046752.1\|WP_158136377.1\|645182_645692_-\|serine-acetyltransferase	gnl\|CDD\|223975	COG1045, CysE, Serine acetyltransferase [Amino acid transport and metabolism].	2.75419e-28
NZ_CP046752.1\|WP_158135110.1\|646874_647417_-\|serine-acetyltransferase	gnl\|CDD\|223975	COG1045, CysE, Serine acetyltransferase [Amino acid transport and metabolism].	4.09916e-39

>NZ_CP046752.1|WP_158136375.1|637583_638996_-|MBL-fold-metallo-hydrolase
MDIIHHGAKDGVTGSCHQLQIEQDGFTSSLLIDCGLFQGRESRPNLDIEFDISTVEALLITHCHIDHIGRIPWLLAKGFTGPIFTTEASAALLPLMLEDSLKLQLGLNKKQCQKFIERIEKQIKPVPYHCWIQQRLASFDSVSIRFSPAGHILGSAFIEIKLPNRQVVVFSGDLGPTNTPLLVDPQSPYQADILVLESTYGYKSTHGVKERALHLFDIIHRSLLDGGVILIPAFSVGRTQELLFDIENIIADTIYRCGLKEPIPINWQSLPVILDSPLAQKITEQYQQFQHLWAKEAKDKVYHGRHPLSFSQCITIEDHSDHLALINRLQKSGEPAIVVAASGMCTGGRIMNYLKALLPDSRTDVIFAGYQAEGTLGRELLDGALEVSIDKKSVEVNACIHQMSGYSAHAAQQDLLAFVDGIEHKPKRIHVIHGEEAAQRALADKLMILYPEIEVVCGVDMGGDSGKEGK
>NZ_CP046752.1|WP_158135094.1|637079_637433_-|four-helix-bundle-protein
MRCKDLEIWKRSYQLSVSVNMLMKDCRDFGLKDQICRASVSIPSNISEGAERGSNRDFIRFLYFSKGSCAELYTQLMMVRDFKYADECIVLPLLEEATRVNKMIGSYIHYLKKVEQR
>NZ_CP046752.1|WP_158135092.1|634726_636964_+|FAD-dependent-5-carboxymethylaminomethyl-2-thiouridine(34)-oxidoreductase-MnmC
MSTQDTNQHPAKIENAVLDWNELGTPVSNDFDDVYFSNANGLEETRYVFLQQNGLPDRWNDFSRRRFVVAETGFGTGLNFLALWQQFKAFRAENPDAIVKELHFISFEKFPVTLDDLKKAHLSWPELSDLAQQLHAHYPPAVADCHRIILEDGLITLDLWFGDIQDCMPQVWTGDEGIVDAWFLDGFAPSKNLAMWNLDVYKGMRNLARSGCTLATFTAAGFVRRELIEAGFEMKKAKGFGHKREMLTGTIGERSAPSNTKPWYHISARAENDTAQTLNDIAIIGGGVASAATALSLVRRGQTVTLYCKDEKPAQGASGNKQGAVYPLLNGNHNALSRFFAPAFIFARQFVEQAAQNSQFDHDWCGVVQLAFGEKMGEEGNIGREGKEGKKGGEGKAGTEGKEGEDTSLLVSSDESKERQEEGIKGGEKGADMRNKQRIKLDKMLAGGFPNELICALDYQQTRKITGVETGFDGVNYPLGGWLCPKELTRALIKQAQATGLLTLHTQSEVCKLQQESDQRWQLQFSDGQSKQHACVVIANGHRFTDFEQTANIPAYSVRGQVSHIPTNEQISKLKTVLCYDGYLTPENPHSHTHCIGASYDRNSVDLTFSEQNQHDNRQRLIDCLPQAEWAKSVDVSDNQARVGVRCATRDHLPFMGNVCRYDELLTQYENLKETQASADKVPVYNNLFALIGLGSRGLSSAPLVGEIMASQICGDPLPMPLSVLEALHPGRMWVRKLVKGRKGK
>NZ_CP046752.1|WP_005298224.1|633322_634537_-|beta-ketoacyl-ACP-synthase-I
MKRAVITGMGIISSIGNNVEEVLESLKAGKSGINFSEQFAEMKLRSQVWGDLKINPAEHIDRKQMRFMGNAAAYAFLSMEQAIADSGLTEDQVSNERTGLVAGSGGASSMNQVAAVDILREKGVKRVGPYMVPRTMSSTVSACLATPFKIRGVNYTMSSACATSAHCIGHAVELIQLGKQDVVFAGGGEELDWSLTMMFDAMGALSTKYNDDPSKASRTYDADRDGFVISGGGGMVVIEELEHALARGAKIYGEVVGYGATSDGYDMVAPSGEGAVRCMKMAMQDLDAPVDYINTHGTSTPVGDVKELGAIQELFSENCPAISATKAMTGHALGAAGVHEAIYSTLMLDNNFVAPSINIENLDEAAQGLDIVTEMREQELKTVMSNSFGFGGTNATLVIKKFEG
>NZ_CP046752.1|WP_106224600.1|631242_632409_-|nucleotide-sugar-dehydrogenase
MKITVVGTGYVGLSNAVLLAQNHQVVALDIIQEKVDLINNKLSPIVDAEIEQYLREKPLNLVATTDSETAYDGADFVIIATPTDYDTATNYFNTGSVEAVIKDVMVKNPTATMVIKSTIPVGYTQRIKQELGCENLIFSPEFLREGRALYDNLYPSRIIVGEQSERAQVFAHLLAEGAIKDDIPMLFTNSTEAEAVKLFSNTYLAMRVAYFNELDTYAATNGLDARQIIEGVGLDPRIGNHYNNPSFGYGGYCLPKDTKQLRANYCDVPNNIIGAIVDANTTRKDFIADSIIAKQPKVVGVYRLIMKSGSDNFRASSIQGIMKRIKAKGIEVVVYEPVLKEDDFFNSKVIRDLDTFKAMSDVIVSNRMAQELADVADKVYTRDLFGAD
>NZ_CP046752.1|WP_158135090.1|629891_631076_-|DUF3410-domain-containing-protein
MKILIDENMPYAHELFSQLGEVIAKPGRSLTPADLVDIDALMIRSVTKVNRELLTQANKLKFVGTATAGDDHVDQALLAEKGITFTAAPGCNKVGVAEYVISSLMVLGQQHGFSIFDKTIGIIGAGNVGTYLAQCLDALGIRYLLNDPLKQEQGDPRQFHTVDEILAQCDVVTLHTPITRTGLYPTHHLVDSAFLAKMQNNAILINAARGPVVDNQALKQALIDSQQGEKTLTAVLDVFEQEPLVDLELLPLLAFATPHIAGYGLEGKARGTTMVFNAFCQFIGSQLYADAKELLPVAPIPYVQLSRIWDEASLFNLTQLIYDVRKDDGIFRFEMFKTGDDSSQMASAFDQMRKNYWDRREYSAITVAGEAAFAVESLAKLGFTVVEETHESGI
>NZ_CP046752.1|WP_005298228.1|628894_629908_-|aspartate-semialdehyde-dehydrogenase
MSQEFDIAILGATGAVGEAMVEVLEERQFPVRNLYLLASDRSAGKVLRFKGKSARVTDVEDFDWSQVQIALFSAGAEASERWAPIAADEGVIVIDNTSRFRYDYDVPLVIPEVNPEAIAEYRNRNIIANPNCSTIQMLVALKPIHDAYGIERINVATYQSVSGSGKKGVDELAGQTAKLLNGLPVETNAYPKQIAFNCLPHIDQFMDNGYTKEEMKMVWETQKIFCDPNIRVNPTCVRVPVFYGHAEAVHVETAQPVNIEEALQLLENAEGIELFHGAEYPTQVSDATGKDHVMVARVREDISHPCGLNMWVVADNVRKGAATNAVQIAEKLISDYI
>NZ_CP046752.1|WP_158135088.1|624668_628661_-|hypothetical-protein
MSELSQALKRILLPVALATAFGGIAPAYANTVRIVGPENEDPNAWVQHSEQMRSSSFDYVKTPNKPYTNMRRYGPTSAKETLWSIASRHRPNNSVSVYQVIGAIKHINPQAFENNNIHGLIPGSYLVMPTLAQVKREDTQLVRRVLEQDKLREPYASKNKKTATSKPSAKKTVVKKAPVKHAAPASQTRSQTKAQPKPQTKPAVNPAKSTSTTVESADHFTIPAKPTVPANKVSPSTNTATKAALATVATATVLGPMAVDAGEPITEQSSATKVNTEQSKAITSAPAQVTSSATEGDNTGANTVSSQSNTASVQRDGAIPPKPQDVSANVAASLPQDVSNPLNASDEQLTQLIESNHMLKVRLAEMQQEMASLREQVGDDDEFRNEVINFIRQQRQQEQAVPEENKTSWLNQLADNPTALIAAGLIPGGLLAGLLAFFLYRRGKKEEQEEQAEKNSQLPLIDDASSSEPNLDSEDKLDELDDLLFDDDLFADGNDKLEQSLDRDLKQSEKTGLSESELSEVKLSESKPSESETSQSDPAPEPNFFLDDFDLNDDFDVDMSSKSVSVNGEEAALGLEEMERAIDQMDSSHSDEDLAAQWERSLQQEKVDIDSNDFDLAEGLDESFEPLEPKSEQELLDQSMLDDLLVDIDSQLEEPVTSEAASDVVSNDRASLEPQLEQEPFTSPTVEDSVQKTIDELDISSEELAEESANPTSNLSAESQTIPEVETAISESSTQLLDELITDEDDLLGADLDIDLDENSVQLLDELIPDEDDEIVLEQPLDLEENSTALLDELVDDWGEKPTEAIDATVEQSQEIEPLQTQVAEEDIDDILDQFLDQELEQHTLADEDQESSSHDYLAPEAKPLTVEELERELDRQEAEEKQSLAQAIDEFPIFDEQAALDELGGREPNSHAIPETKAQSESHIEAFEFDDLPEFDEQSALNDPEAESLLDEELALSDEDQQRALDNVVRQLQEAVEASERYQQAPELLDSIDTKLSESKETPPQELTSSEEITKESISEPSMTDASSEPSAFDEHKKKDYDFAHYDPASLPEFNEDEALQASFEEQYELEQYEREKGFSTQRPPHPIQDDYVANSAQPLPSEFDHELVESAGLDMAALLTDPDLGLADAERDGLLAHVHNDTQDDDGLDSDEQALWHQVSQDPSLENEDWSQQPSLAKDDIDSVIESIEHELEPAQEKGAYKAFQQAEELTLPEAGSELISVAQDPKPHSFISIDELMKETQGDGSALAQELDAQPLKLDVGLDEFPDVLTNIAHTDVDDHSELASKLDLAKAYLEMNDKEGAIELLEEVTAKADGAVKAEAEKLLNN
>NZ_CP046752.1|WP_158135086.1|624193_624388_-|hypothetical-protein
MKKILTVLSIFILSACNSDNDSLKETVSSNSADVVETETYQLTPVDAPSSFLSHSWSKHVAHLS
>NZ_CP046752.1|WP_158135084.1|623936_624197_-|hypothetical-protein
MNESDKQAISFNFVAPELKQDEKYCFTFKGITGDHRYITNTTLTVVAPTLEVYVDHASLPSLQQLVHIIQAKDEYPSNQRFVSWGV
>NZ_CP046752.1|WP_158135096.1|639649_640261_+|N-acetylmuramoyl-L-alanine-amidase
MKQPLFILDAGHGGIINGQYQTAGKRSPIWSDGSQLFEGEFNRAVVAGISQQLTQRNIKHHILVPEQRDIHLRDRVRRANRLAKHYLRYQCILISVHANAGGGSGFEVFTSKGKTRSDDIADHFALAFKDVFPNKPLRADLRDGDYDKDRSFYILRYTSMPAILTENFFMDNEQECKEILMTSIGREKIVKYHVKGIRRILGA
>NZ_CP046752.1|WP_158135098.1|640360_641230_+|hypothetical-protein
MNKHYIAIHGRSNKPPAHILEDSWLRAINDGRKQTNQSLINKSQFSMAYYADVFYQQPLYFDPEPYLPSLPFLPYLPDIPSNHPPIPLAVDEDHLSEMMEQNKWRLDNLFFEPLLSEFGVYRALNYLSKPLLRYWLTDVYHYFHDPAFALEIEKPLIRLLQQYRHHSITLISHSLGTVIAYNVLQKLAAQRTTQDITIDKWITLGSPLGLASVKAQLERNLQGSLAVPDNVSAWHNYSDKRDIVCIDGDLADDFARNNAGVSVQDFQIVNAYPGNPHKSYGYLRVASSE
>NZ_CP046752.1|WP_158135100.1|641423_642317_-|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKSHIKKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQFIVNECVNAGIKEIVLVTHSSKNAIENHFDTSFELEATLEARVKRQLLDEVQNICPKDVTVMHVRQGHAKGLGHAVLCAKPLVGDAPFAVVLPDVILDEYTADQSKENLAAMLQRYEETGASQIMVEPVPMSDVSKYGVVDCNGTELVAGESCPMTRMVEKPAVEDAPSNLAVVGRYVLSHKIWDKLAITPPGAGDEIQLTDAIDMLMAEETVEAFHMSGKSHDCGDKLGYLKAFVEYGMRHKDLGEDFKAYLKASN
>NZ_CP046752.1|WP_158135102.1|642322_643489_-|nucleotide-sugar-dehydrogenase
MKITIAGTGYVGLSNAMLLAQHHEVIAVDIIKEKVKLLNDKISPIVDKEIEDFLQNKELNFTATLDKELAYKDAEYVVIATPTDYDTENNYFNTSSVEAVIKDVMAINPNAVMVIKSTIPVGYTKQIKEQFGCENIIFSPEFLREGRALYDNLYPSRIIVGERSTRAEIFANLLVEGAIKQDIPVLFTDSTEAEAVKLFSNTYLAMRVAYFNELDTYAATNGLDARQIIEGVGLDPRIGNHYNNPSFGYGGYCLPKDTKQLRANYRDVPNNIIGAIVDANTTRKDFIADSIIAKNPKCVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGIEVVVHEPVLKEKEFFHSLVINDLNEFKQSCDVIVSNRMSDELSDVADKVYTRDLFGAD
>NZ_CP046752.1|WP_158135104.1|643503_644634_-|glycosyltransferase
MKNKKIAHIQLLPLLTGVQRVSLDELTRLNRNDFTPYMICQQSGPMTDECEKNNINCLYIPTLVREISPLKDFLAFWNLYRLCKKHKFDIVHTHSSKTGVIGRLAAKLAGVPMVVHTVHGYAFPAAKNKLEKNIFLAMEWLGTKCSDKVICLHDADKKIAEEKLGAKASQIMVLANGVNLSKFNPPTLLQKQDIRSELGLPVNATVVGMVGRLWEQKNPKDLLTAAIDILKTRSDVHFVFAGDGELRAELEHRTNYHGVSSNIHFLGWRNDTESVLKAFDIFVLPSLWEGMPLAILEAQATGLPCVVSNIQGNNHLVYNEKNGYLFELNNNEQLIHSILALVDKSHRRDQMGTFALNKIKQDNDIERRIIILSSHY
>NZ_CP046752.1|WP_158135106.1|644647_645181_-|acyltransferase
MFFLLKITMLLLPFLSKNEFFLKVYSKYEVESYLKKGCVIGNKTRLYRVTLSSSFKGDKFFIGDNCTLTNCILLGHDASPSLYIKDLINNNNYYLPGARSSYRNPIVIGNNVFVGYGSIILPGVKIGDNVVIAAGSVVINDIPSSGVYGGNPARFIKPLDSFLDKYRMLLKENPELF
>NZ_CP046752.1|WP_158136377.1|645182_645692_-|serine-acetyltransferase
MIDSIKKDMAAHKINNLLYILLPNDKANILQFQIYMRLLEFIVNFRYLMPLYLIFKFLYLKKSEQLGFSIPINTFGAGLWIVHKGTIVVSSDAKIGSNCRIHVCVNIGKNPLGNDNAPKIGDNCYIGPGAKIYGDIYISDNTIIGANSVVNKSFYQPGKLLGIPAKRYD
>NZ_CP046752.1|WP_158135108.1|645712_646882_-|glycosyltransferase
MNDKSKLFITSKFFFPNIGGVENSLKEISKSLSDEYDVYIYTTNINNVSDDSLLLSEEFDGYNIKRIDCNHKNKYIRELLFYIKMIWSLRKEAKKSINSVIIARDHFSVINAWFAGFREISYLVPGVVKYQNNKVNHGAGKSLLFLKIENIIQKISFRLSKRIFVFSKNMMKQVTDVDNKSEVKIYLCKPGVNFNRFKIATFEEKKTLRKKYNIPSDKYIILGLARFVKAKGYENLILSMKYLSDDFYLILVGSGPEYDNYNQIISDENIKNIKIFPPTSTPNEFYKLSDVFAMTSIYEPLGQTILESQVSGLPNLYHLPSKDVITAVDEIIYKEYSFPIKENNPLSISESIVNAKLSTSNILSRKMRASIKEKFSWYKLGVLLTCKEK
>NZ_CP046752.1|WP_158135110.1|646874_647417_-|serine-acetyltransferase
MVCKYIKSDYFRYSGVEDFKLFVFLKMYFCENGFKFQFWLRLCKSRNLMIRAISYLQWFRFSRKYSLYINPKTKIGYGLYLGHGLSIVINSTAEIGNNVNIGHFTTIGSNKGKAAIIGNNVYIAPNVSIVEDVTIGNNIIIGTGSIVLSNISDGCTCAGVPSRVINKISVNKFIKNMYYE
>NZ_CP046752.1|WP_158135112.1|647416_648430_-|hypothetical-protein
MIVYYIANLFLFPVGYGYKKSNSQLRLLILFLLSTVYSLFFGLRYQVGVDWKNYITAFEFYNSNQDYFSLEVGYKILNIISYNLGYDIQFIIIITTLIVFFLSFYSLYFIKINPCYYIGVVFPYFIVMGAMNYTRQGVALSFFLLALSFLFNNKRVLFVIFLLFGCTFHVSLIIFLPLLFYRMKKSYLISIFLVLAIPFILLVNFQYSMYIQADFDSKGLLLRSAFVILSSVVLFLNRRVWDNSKYSNIYYVSMLSPVFVFTVSIVSTTMADRISYYFILLSALCCFLLCQFNGIHFKKYIVPLLFICSLTVFIIWSNFSSYIPYYEFKSQVFSGIL

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP046752_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046752_4

945492-946386

Orphan

Consensus_repeat	Method
CGGGAGGATTCGAACCTCCGACCGCCTGGTTCGTAGCCAGGTACTCTATCCAGCTGAGCTACG	PILER-CR

7 spacers

The CRISPR arrays of NZ_CP046752_4

>merge|NZ_CP046752|4|945492-946386|PILER-CR
CGGGAGGATTCGAACCTCCGACCGCCTGGTTCGTAGCCAGGTACTCTATCCAGCTGAGCTACGAGCGCGCAGGGTTGTTTGACAATTTTATCTTCATCAAACTTGAAGAATGGCGCGTCCGGGAGGATTCGAACCTCCGACCGCCTGGTTCGTAGCCAGGTACTCTATCCAGCTGAGCTACGGACGCGCAGGCTAATATCAATCGGTTAGATCAATACTATTTAAATTATGGCGCGCTCGGGAGGATTCGAACCTCCGACCGCCTGGTTCGTAGCCAGGTACTCTATCCAGCTGAGCTACGAGCGCGCAGGGTTGTTTGATAATTTTATCTTCATCAAACTTGAAGAATGGCGCGTCCGGGAGGATTCGAACCTCCGACCGCCTGGTTCGTAGCCAGGTACTCTATCCAGCTGAGCTACGGACGCGCAGGCTAATATCAATCGGTTAGATCAATACTATTTAAATTATGGCGCGCTCGGGAGGATTCGAACCTCCGACCGCCTGGTTCGTAGCCAGGTACTCTATCCAGCTGAGCTACGAGCGCGCAGAGTTGTTTGATAATTTTATCTTCATCAAACTTGAAGAATGGCGCGTCCGGGAGGATTCGAACCTCCGACCGCCTGGTTCGTAGCCAGGTACTCTATCCAGCTGAGCTACGGACGCGCAGGCTAATATCAATCGGTTAGATCAATACTATTTAAATTATGGCGCGCTCGGAGGATTCGAACCTCCGACCGCCTGGTTCGTAGCCAGGTACTCTATCCAGCTGAGCTACGAGCGCGCAGGGTTGTTTGATAATTTTATCTTCATCAAACTTGAAGAATGGCGCGTCCGGGAGGATTCGAACCTCCGACCGCCTGGTTCGTAGCCAGGTACTCTATCCAGCTGAGCTACG

>NZ_CP046752|4|1|945492-946386|PILER-CR
CGGGAGGATTCGAACCTCCGACCGCCTGGTTCGTAGCCAGGTACTCTATCCAGCTGAGCTACG	AGCGCGCAGGGTTGTTTGACAATTTTATCTTCATCAAACTTGAAGAATGGCGCGTC
CGGGAGGATTCGAACCTCCGACCGCCTGGTTCGTAGCCAGGTACTCTATCCAGCTGAGCTACG	GACGCGCAGGCTAATATCAATCGGTTAGATCAATACTATTTAAATTATGGCGCGCT
CGGGAGGATTCGAACCTCCGACCGCCTGGTTCGTAGCCAGGTACTCTATCCAGCTGAGCTACG	AGCGCGCAGGGTTGTTTGATAATTTTATCTTCATCAAACTTGAAGAATGGCGCGTC
CGGGAGGATTCGAACCTCCGACCGCCTGGTTCGTAGCCAGGTACTCTATCCAGCTGAGCTACG	GACGCGCAGGCTAATATCAATCGGTTAGATCAATACTATTTAAATTATGGCGCGCT
CGGGAGGATTCGAACCTCCGACCGCCTGGTTCGTAGCCAGGTACTCTATCCAGCTGAGCTACG	AGCGCGCAGAGTTGTTTGATAATTTTATCTTCATCAAACTTGAAGAATGGCGCGTC
CGGGAGGATTCGAACCTCCGACCGCCTGGTTCGTAGCCAGGTACTCTATCCAGCTGAGCTACG	GACGCGCAGGCTAATATCAATCGGTTAGATCAATACTATTTAAATTATGGCGCGC
TCGGAGGATTCGAACCTCCGACCGCCTGGTTCGTAGCCAGGTACTCTATCCAGCTGAGCTACG	AGCGCGCAGGGTTGTTTGATAATTTTATCTTCATCAAACTTGAAGAATGGCGCGTC
CGGGAGGATTCGAACCTCCGACCGCCTGGTTCGTAGCCAGGTACTCTATCCAGCTGAGCTACG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046752.1\|WP_106142318.1\|959277_960114_-\|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl\|CDD\|236782
NZ_CP046752.1\|WP_158135279.1\|940807_943654_-\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NZ_CP046752.1\|WP_158135275.1\|936417_937695_+\|DUF21-domain-containing-protein	unknown	unknown	gnl\|CDD\|236933
NZ_CP046752.1\|WP_069532064.1\|937799_938315_-\|S-ribosylhomocysteine-lyase	unknown	unknown	gnl\|CDD\|179399
NZ_CP046752.1\|WP_158136388.1\|955502_958073_+\|DNA-mismatch-repair-protein-MutS	unknown	unknown	gnl\|CDD\|235444
NZ_CP046752.1\|WP_069532057.1\|935577_936375_+\|inner-membrane-protein-YpjD	unknown	unknown	gnl\|CDD\|226621
NZ_CP046752.1\|WP_154139485.1\|953575_954631_-\|recombinase-RecA	unknown	unknown	gnl\|CDD\|236476
NZ_CP046752.1\|WP_005297846.1\|933585_933837_-\|30S-ribosomal-protein-S16	unknown	unknown	gnl\|CDD\|234588
NZ_CP046752.1\|WP_112163704.1\|952154_953387_-\|voltage-gated-potassium-channel-protein	unknown	unknown	gnl\|CDD\|236711
NZ_CP046752.1\|WP_005297770.1\|960117_960747_-\|protein-L-isoaspartate(D-aspartate)-O-methyltransferase	unknown	unknown	gnl\|CDD\|178974
NZ_CP046752.1\|WP_106338530.1\|944133_945087_-\|NADP-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|176191
NZ_CP046752.1\|WP_158135277.1\|939087_940653_-\|glutamate--cysteine-ligase	unknown	unknown	gnl\|CDD\|235001
NZ_CP046752.1\|WP_005297826.1\|947722_947920_-\|carbon-storage-regulator-CsrA	unknown	unknown	gnl\|CDD\|234973
NZ_CP046752.1\|WP_005297844.1\|934008_935376_-\|signal-recognition-particle-protein	unknown	unknown	gnl\|CDD\|236780
NZ_CP046752.1\|WP_158135281.1\|954768_955257_-\|nicotinamide-nucleotide-amidase	unknown	unknown	gnl\|CDD\|179627
NZ_CP046752.1\|WP_109374756.1\|949256_951878_-\|alanine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234701
NZ_CP046752.1\|WP_036763274.1\|933025_933559_-\|ribosome-maturation-factor-RimM	unknown	unknown	gnl\|CDD\|234650
NZ_CP046752.1\|WP_036763265.1\|943666_944113_-\|DedA-family-protein	unknown	unknown	gnl\|CDD\|224159
NZ_CP046752.1\|WP_158136389.1\|960863_961907_-\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP046752.1\|WP_068968307.1\|958222_959224_-\|RNA-polymerase-sigma-factor-RpoS	unknown	unknown	gnl\|CDD\|235548

Protein	Function_ID	Function_description	E-value
NZ_CP046752.1\|WP_106142318.1\|959277_960114_-\|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl\|CDD\|236782	PRK10871, nlpD, murein hydrolase activator NlpD.	1.01536e-94
NZ_CP046752.1\|WP_158135279.1\|940807_943654_-\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	1.58117e-78
NZ_CP046752.1\|WP_158135275.1\|936417_937695_+\|DUF21-domain-containing-protein	gnl\|CDD\|236933	PRK11573, PRK11573, hypothetical protein; Provisional.	0
NZ_CP046752.1\|WP_069532064.1\|937799_938315_-\|S-ribosylhomocysteine-lyase	gnl\|CDD\|179399	PRK02260, PRK02260, S-ribosylhomocysteine lyase.	2.90691e-103
NZ_CP046752.1\|WP_158136388.1\|955502_958073_+\|DNA-mismatch-repair-protein-MutS	gnl\|CDD\|235444	PRK05399, PRK05399, DNA mismatch repair protein MutS; Provisional.	0
NZ_CP046752.1\|WP_069532057.1\|935577_936375_+\|inner-membrane-protein-YpjD	gnl\|CDD\|226621	COG4137, COG4137, ABC-type uncharacterized transport system, permease component [General function prediction only].	2.24037e-91
NZ_CP046752.1\|WP_154139485.1\|953575_954631_-\|recombinase-RecA	gnl\|CDD\|236476	PRK09354, recA, recombinase A; Provisional.	0
NZ_CP046752.1\|WP_005297846.1\|933585_933837_-\|30S-ribosomal-protein-S16	gnl\|CDD\|234588	PRK00040, rpsP, 30S ribosomal protein S16; Reviewed.	7.76102e-42
NZ_CP046752.1\|WP_112163704.1\|952154_953387_-\|voltage-gated-potassium-channel-protein	gnl\|CDD\|236711	PRK10537, PRK10537, voltage-gated potassium channel protein.	1.13849e-146
NZ_CP046752.1\|WP_005297770.1\|960117_960747_-\|protein-L-isoaspartate(D-aspartate)-O-methyltransferase	gnl\|CDD\|178974	PRK00312, pcm, protein-L-isoaspartate(D-aspartate) O-methyltransferase.	1.11401e-121
NZ_CP046752.1\|WP_106338530.1\|944133_945087_-\|NADP-dependent-oxidoreductase	gnl\|CDD\|176191	cd05289, MDR_like_2, alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases. Members identified as zinc-dependent alcohol dehydrogenases and quinone oxidoreductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	8.95334e-96
NZ_CP046752.1\|WP_158135277.1\|939087_940653_-\|glutamate--cysteine-ligase	gnl\|CDD\|235001	PRK02107, PRK02107, glutamate--cysteine ligase; Provisional.	0
NZ_CP046752.1\|WP_005297826.1\|947722_947920_-\|carbon-storage-regulator-CsrA	gnl\|CDD\|234973	PRK01712, PRK01712, carbon storage regulator CsrA.	2.67995e-35
NZ_CP046752.1\|WP_005297844.1\|934008_935376_-\|signal-recognition-particle-protein	gnl\|CDD\|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0
NZ_CP046752.1\|WP_158135281.1\|954768_955257_-\|nicotinamide-nucleotide-amidase	gnl\|CDD\|179627	PRK03661, PRK03661, nicotinamide-nucleotide amidase.	4.43136e-70
NZ_CP046752.1\|WP_109374756.1\|949256_951878_-\|alanine--tRNA-ligase	gnl\|CDD\|234701	PRK00252, alaS, alanyl-tRNA synthetase; Reviewed.	0
NZ_CP046752.1\|WP_036763274.1\|933025_933559_-\|ribosome-maturation-factor-RimM	gnl\|CDD\|234650	PRK00122, rimM, 16S rRNA-processing protein RimM; Provisional.	3.37038e-75
NZ_CP046752.1\|WP_036763265.1\|943666_944113_-\|DedA-family-protein	gnl\|CDD\|224159	COG1238, COG1238, Predicted membrane protein [Function unknown].	7.26568e-36
NZ_CP046752.1\|WP_158136389.1\|960863_961907_-\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	8.15265e-157
NZ_CP046752.1\|WP_068968307.1\|958222_959224_-\|RNA-polymerase-sigma-factor-RpoS	gnl\|CDD\|235548	PRK05657, PRK05657, RNA polymerase sigma factor RpoS; Validated.	0

>NZ_CP046752.1|WP_106338530.1|944133_945087_-|NADP-dependent-oxidoreductase
MSTYQQVVISQFGGVDVLQCQLTELPTVLEPHQVLVKVDYCAVNPIDAKIRQGSNFVAQQIQNALPWGLGYDIAGKVVSVGSTISALKTGQRVAGLIGFPLQGGGYSQYCVVDWQALSVLPEQVDLRQAAAVPLAGLTAMQAIELADIQPQERVLVLAGSGGVGHLALQLLKALPCQVLATGSSTNQAFIASLGAEAIDYDKVDFVSLEPVDVIIDLVGGKTGLAALAALKPSGRIITVPTVTQAEIIAQAQDLGFYAQGMVVQPDKIQQDMLLQLIAEKKLRVHIDQQFDFSSVAQAHQHIESGRTRGKLVLATLS
>NZ_CP046752.1|WP_036763265.1|943666_944113_-|DedA-family-protein
MLDLVNGQSGLWVLFSTGFLSATLLPGGSEANLIASLNLGDNAPWLLVLVATLGNSLGGMTNYWLGRLIPDKTSQEKHGHKAIRWVKKYGYWSLFFSWLPIIGDPLCLAAGWLRLRPWLSFVIIVVGKAARYSVLAVIVLGLFPTFSH
>NZ_CP046752.1|WP_158135279.1|940807_943654_-|insulinase-family-protein
MQKWILPLALLSVTNTTWAAKQSDVPLPKGVSFIEQVKPEPGKAVIPFRKYELSNGLTVILHQDKSDPLVHVDMTYHVGSAREEVGKSGFAHFFEHMMFQGSKHVGDQEHFRLITEAGGTLNGSTNRDRTNYYETVPANQLEKVLWLESDRMGFLLDAVSQKKFEIQRSTVKNERAERYENRPYGLVYERMGEALFPRDHPYSWQTIGYVADLDRVDVNDLKAFFLRWYGPNNATLTIGGDIDIAQTLDWVEKYFGSIPRGPEVNNAPKQPVTLKADRYITLEDKVQQPMLMMGWPTSYRGAKDEASLDMLAQIIGDGTNSLLYQKLVKTGQVVDAGAFNDCAELACTMYVYAIGPSGEKGNLKSIRGKVMEIVNSLEKQGVKQQAVDEIKGVAESSAIFGLQSVSGKVAQLAAYQTFYGDPNHLGVELDNIRKVSPSSIEAAYNQYIYQHPNVTLSVVPQGKLDLVAAKTNFTPEPRKIPEHQKINDDQLTLRTAKDNFDRSVMPQPSKPVEAMMPSLYNVTLANGIKILGTQYDETPTVELQLVVPAGRRYEAEGKAGLAQLTAAMMNEATTKASAEHIASELDKLGSSVSFDAGLYGTTITLSSLAKNLKPTLAILEQRLFHPAFAQADFDRLKKLALEGLVYEHQRPEWLAGQATRDVMFKGTVFSQAPEGTKASIESITLADVKDFYQRYYTPNGADMVVVGDIKPQILQQDLASLGQWKGQAAPTYHTPKLPSIEKPAIWMVDKPGAPQTIIRLVRQGLPYDATGELYKTQLANFNLAGNFNSRINLNLREDKGYTYGAGGYLTGGKELGLATFYAQVRADASLAATKEFLAELKKMSQGGLTDKEMKFMRLAVGQQDALKYETPAKKAQLLGQMLTYSLPKDFVEQRNKIAATISKSELDKLAKKWFNPQDYQIIVVGDVAKLKPQFATLGLPIHVIKPQQ
>NZ_CP046752.1|WP_158135277.1|939087_940653_-|glutamate--cysteine-ligase
MDFSQRLQQVSANKDALKKFGRGLEREALRITTDHQLSDQPHPVQLGSALTNKWITTDFAESLLEFITPVSRSVDDLLAQLSDIHQFTYSKMNGERLWPMSMPCFVGDQDDITLAQYGSSNVGRMKTLYREGLKRRYGSVMQIISGVHFNFSFPDEFWDQLFGPQNEQERQESRSAAYFGLIRNYYRFGWLIPYLFGSSPALCGSFLQGKPIKDKFSKIGQGTYYLEKATALRLSDLGYTNNAQSGLKIGFNSLEQYLDGLNKAIRTPSAEFADIGVKVGDEYRQLNSNVLQIENELYAPIRPKRVAKSGEKPSEALKRAGVEYIEVRSLDVNPFSPIGVVEDQIRFLDIFLTWAVLSPSSDMTDCELGCWRENWSKVILDGRNPDLVLTIGCHGEQLTLKEWGSRVFADFAQVAKMLDEANGTTAYQETCERLLGWIEHPERTLSAQLLEQIKQFDGIGKVGDELAKQHAEFMAHRQYQFYNEAQFETEAKESIAKQQQIEANDTVSFDDYLAAYFADIK
>NZ_CP046752.1|WP_069532064.1|937799_938315_-|S-ribosylhomocysteine-lyase
MPLLDSFTVDHTKMQAPAVRVAKTMQTPKGDTITVFDLRFCRPNNEILSERGIHTLEHLFAGFMRQHLNSDTVEIIDISPMGCRTGFYMSLIGEPQETVVAQAWLDAMQDVLLVDSQDKIPELNEYQCGTYAMHSLAEAQAIAQSIITAGVGVNQNDDLALPAEMLVQLKV
>NZ_CP046752.1|WP_158135275.1|936417_937695_+|DUF21-domain-containing-protein
MEDISTGVLFALLILMLVLSAYFSGSETGMMALNRYKLRHLANQGHKGAQRVEKLLARPERLIGLILIGNNLVNILASAIATILGMRLYGDAGVAIATGALTLVVLVCSEVTPKTLAAQYPERISYASSILLNALMKVLYPLVWIVNGITASFLFLFGLRNKNGGGNPLTSEELRTVVNEAGSLIPRRHQDMLLSILDLENVTVVDVMIPRNEIAAININDDWKSIARQLSHSAHGRIVLYRDTIDEVVGMLRVREAYRMMLDKNEFSKENLLRAADEVYFIPEGTPLNIQLLKFQRNKERIGLIVDEYGDIQGLITLEDILEEIVGEFTTSIAPTLAEEITPQSDGSLLIEGSANIRDLNKSLKWKLPTDGPRTLNGLILEYLEYIPDSPISFRIGNKKMEVVEVSDNMIKLVKVLPMNRKNDK
>NZ_CP046752.1|WP_069532057.1|935577_936375_+|inner-membrane-protein-YpjD
MDILIAVAAIGCYIAALAFIIPGLSNSNGIKTRPVFISALLAIALHILLLKDLILGVHGQNLSILNVASLISVIIAIITTFAMLKMRIWFVLPVVYSFAAINLAAATLLPGAFITHLEANPQVLLHISLALFSYSTLMIATLYAIQLAWLDNKLKSKKSLQLNPNIPPLMMVERQLFKLILVGNGLLTVTLLTGLLFLQDMFAQGKTHKAVLSILAWLVYSVLLWGHYRQGWRGRRVIWISLVGAFLLTLAYFGSRFVKEIIIGG
>NZ_CP046752.1|WP_005297844.1|934008_935376_-|signal-recognition-particle-protein
MFENLTERLSRTLKNVSGRGRLTDDNIKDTLREVRMALLEADVALPVVREFVNRVKERAVGTEVSKSLTPGQEFIKIVQAELEAVMGEQNEELNLASQPPAVILMAGLQGAGKTTSVGKLSKVLKERNKKKVLVVSADVYRPAAIKQLETLATDLGVDFFPSTPDQKPVDIAKAAVAHAKLKFYDVLIVDTAGRLHVDSEMMDEIKDVHQVLNPVETLFVVDAMTGQDAANTAKAFNDALPLTGVILTKVDGDARGGAALSVRHITGKPIKFLGVGEKTDALEPFHPDRVASRILGMGDVLSLIEDIERNVDKDEAEKLAKKFKEKKGFDLEDFRSQLQQMKKMGGMMGMLDKLPGMSQLPGDVKDKVDDKIFVQMEAIINSMTPGERERPDLIKGSRKKRIAAGSGTQVQDVNRLLKQFTQMQKMMKKMQKGGIKNMMRQMKGMMPGGGMFPGR
>NZ_CP046752.1|WP_005297846.1|933585_933837_-|30S-ribosomal-protein-S16
MVTIRLARHGAKKRPFYHIVVADARVSREGRSIEKLGFFNPLAKGQEEALRLDLDRVNHWVGQGAAVSDRVAKLIKDAAKAAA
>NZ_CP046752.1|WP_036763274.1|933025_933559_-|ribosome-maturation-factor-RimM
MSTDNQDIIVVGKLGASYGIKGWLKVFSYTEQSENIFAYSPWLIKVKGEWQAFNVESWKRHGQGMVVKLEGLDVREDAQIFTNAEVAVQAEQLPALSDDEFYWRELYGMSVVTTEGYDLGVVTEILETGSNDVLVVKANLKDAFGQKERLIPFLDEQVIKSIDRTAQRIEVDWDPGF
>NZ_CP046752.1|WP_005297826.1|947722_947920_-|carbon-storage-regulator-CsrA
MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYMRIQAEKETGTPSTGNY
>NZ_CP046752.1|WP_109374756.1|949256_951878_-|alanine--tRNA-ligase
MYMSTDEIRRAYLAFFESKGHQIVESSSLVPANDPTLLFTNAGMNQFKDVFLGLEKRSYTRATTAQRCVRAGGKHNDLENVGFTARHHTFFEMLGNFSFGDYFKHDAIKYAWEFLTTVLELPEDRLLVTIYESDDEAFEIWNKEVGIPADRIVRIGDNKGAPFASDNFWQMGDTGPCGPCTEIFFDHGDHIWGGRPGTPEEDGDRFIEIWNNVFMQYNRQADGTMEPLPKPSVDTGMGIERIAAIMQGVHSNYEIDIFKTLIKDAADIIGYDDLSNQSLRVVADHIRSCAYLIADGVMPSNEGRGYVLRRIIRRAVRHGNKLGAKGAFFYKLVGPLADVMGTAGSELKKQQEMVEKVLKIEEENFGRTLDRGLTILNEALDNLDGSILDGETVFKLYDTYGFPADLTNDVARERGFTIDEEGFEAAMEEQRQRARDAGQFGVDYNNVIKVDADTEFKGYDATDGEGVIVAIYRDGEEVDALAAGEEAIIVLDQTPFYAESGGQCGDTGALAAAGVAFTVADTQKFGHAIGHKGTLTEGALKVGDKLAATVDHVRRGAISLNHSATHLMHAALRKLLGEHVAQKGSLVKPDSLRFDFSHLEAVKPEQLREVERMVNDQIRLNHAIDTEIMDIEAAKEKGAMALFGEKYDDQVRVLSMGDFSTELCGGIHAKRTGDIGLFKIVSEGGIAAGIRRIEAVTGAAAIEALHAQDEQLAKAARLVKSDTASVVNKVEALVSHSKQLEKEIQQLKDKLAAQEGAGLINQAQEINGVKVLIAKLDGADNKALRGMVDELKNQLSSGIVVLGNVSDDKVGLIAGVTKDLIGKVKAGELVNMVAQQVGGKGGGRPDMAQAGGTDASALPAALESAKAWIEERL
>NZ_CP046752.1|WP_112163704.1|952154_953387_-|voltage-gated-potassium-channel-protein
MSSCRTFWHRCWRFIQGSFTTLYAIRHIFIALLVLGNSAFILHVIYGLPIDLVSIFNVKNYEDLNLTFLINAPYFMLGVFIAMSTIGLFFRARISWVICFTLLIINAFYAMQLRPSEEYNFHYSLFTIAVLFLNRKYFSKSSVAAGTIFALISMISLMLTSTYGALYFGDGYKPPINDLSTALYYAIETMTTVGYGDIVPVSEPARLFTISVIIAGITVFATSLTSVLGPAVQSGYERLTKGKTKKMKRKNHFIICGLSSLALNTIQQLIQRKQLVTVIVSPRTQQAAKDLLEELDVVVGDYSDGSVLKQAGVMDAKALLALSDDDADNAFIVLSAIELKTDAHNVALVNDSKNINKVKSVNPDIVISPQQFASDILARVLNGETIDSESIVSSLLNSVQGLNEKQISKD
>NZ_CP046752.1|WP_154139485.1|953575_954631_-|recombinase-RecA
MDENKQKALAAALGQIEKQFGKGSIMKLGDNRTMDIETVSTGSLALDIALGAGGLPMGRIVEIFGPESSGKTTLTLETIASAQRQGKTCAFIDAEHALDPIYAKKLGVDIDQLLVSQPDTGEQALEICDALARSGAVDLIVVDSVAALTPKAEIEGEMGDSHMGLQARMLSQAMRKLTGNLKQSNCMCIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGSIKDGEEVVGNETRIKVVKNKIAAPFKQAETQILYGQGFNRVGELIDLGVKQKLIEKAGAWYSYKGDKIGQGKANAGKYLTENPAIADEIEKQIRELLLTLPQEDTTEDASLDAIEAGEDKAF
>NZ_CP046752.1|WP_158135281.1|954768_955257_-|nicotinamide-nucleotide-amidase
MEHIQALANQLGEALAKQQWVATTAESCTGGGVATAITDIAGSSQWFDRAFITYSNEAKMQMLEVQAETLANYGAVSEPVVEQMAEGALTNSLADISVAISGIAGPTGGTEEKPVGTVWFAWADKQGWRKTMVCQFSGNRNQVRYQAITQAILGMLHHLAEL
>NZ_CP046752.1|WP_158136388.1|955502_958073_+|DNA-mismatch-repair-protein-MutS
MMQQYLKIKAENPDVLLFYRMGDFYELFYDDAKQASQLLDISLTKRGASNGQPIPMAGVPHHAAEGYLAKLVQQGVSVAICEQIGDPATSKGPVERQVVRIVTPGTVSDEALLNERRDNLIAAIFAYNDGFGYATLDITSGRFMLTEPSTEEEMQAELQRTMPAELLYPEDFTYLHLIESFKGKRRRPVWEFELSTARQQLTMQFGTRDLVGFGVEHAERGLCAAGCLLQYVKDTQRTALPHIRAITLDTKDHAVILDAATRRNLELTQNLAGGFDNTLASVLDQTATPMGSRLLKRWLHQPIRDPKQLNGRYNAIGAFKDSGLYSELAGVLRHMGDLERILARLALRSARPRDLARMRIALQNLPELADLLAEVSDPRINELAALAAPMDEVCQLLEHAIIENPPVIIRDGGVLAPGYNAELDEWRDLADGATKYLEELEARERERHDIDSLKVGFNQVHGFYIQVSRGQSHLVPSHYIRRQTLKNAERYIIPELKEHEDKVLNSKSKALALEKKLWDELFDLLMPNLEQLQNMANSLSELDVLANLAERADTLNYCRPQLMDETGIEIEAGRHPVVEQVLSEPFIANPISLNHDRRMLIITGPNMGGKSTYMRQTALIALLAHVGSFVPADSLKIGPLDRIFTRIGASDDLASGRSTFMVEMTETANILHNATQHSLVLMDEIGRGTSTYDGLSLAWASAEWLADKIAAMTLFATHYFELTELPTLMSGLANVHLDAVEHGDEIAFMHAVQEGAASKSYGLAVASLAGVPKSVIKRAKIKLQQLEASGHQQASDVPNPTTTDTPASAKAVRQEHQLSLIPESSEVEEAVARLNPDNMTPREALDELYRLKALLN
>NZ_CP046752.1|WP_068968307.1|958222_959224_-|RNA-polymerase-sigma-factor-RpoS
MSKSSTVTNLDSFDFDDEIELDTGDAVNTKNTAAADDDSAEELSSGSNNQAQKVLDATQLYLGEIGFSPLLTAEEEVLYARRALRGDDVARKRMIESNLRLVVKISRRYSNRGLALLDLVEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMNQTRTIRLPIHVVKELNVYLRTARELAQKLDHEPTAEDIAIQLEKPVDDVNRMLRLNERVSSVDNPISGDADKALLDIIPDEKGGTPEVSTQTDDIKSSIVDWLDELNPKQREVLARRFGLLGYEASTLEDVGREIGLTRERVRQIQVEGLRRLRDMLTHEGLSIESLFDPDEN
>NZ_CP046752.1|WP_106142318.1|959277_960114_-|peptidoglycan-DD-metalloendopeptidase-family-protein
MSVIQKIVKPVGLIALSSVIFGCSSHTPAPVTSLTKDYSQLARGSFHGSDYVVQKGDTLYFISYIAGQDVKDLIAYNNLTPPYTIYPGQRLNVRGSNSYSTASRSTSTTVTKPVTQTKPAEQKTNNKKVDQNQAKEYSQKATDNKPVTKPTPKPVAPAVTGWLWPAKGKVISRFSSTNKGIDIAGSRGEAVNATAAGKVVYAGNALRGYGNLVIIKHNDDYLSAYAHNDKLLVKEQQQVTAGQKIALMGDTGADSVKLHFEIRYKGKSVDPLRYLPRQ
>NZ_CP046752.1|WP_005297770.1|960117_960747_-|protein-L-isoaspartate(D-aspartate)-O-methyltransferase
MRYLSERHSLVAFLRNKGIDNERVLHAIAAVPRERFVDEAFSYQAYENNALPIGHGQTISQPYMVARMTSLLELEPSSSVLEIGTGSGYQTAVLAHLVDHVCSVERIKVLQWQAKRRLKSLDLHNVSTKHGDGWQGWANRGPFDAIIVTAAPECVPSDLLAQLADGGRLVLPVGEDSQVLKKIVRIGDRFVHHSIEAVRFVPLIAGELA
>NZ_CP046752.1|WP_158136389.1|960863_961907_-|tRNA-pseudouridine(13)-synthase-TruD
MDSFAYLYGKPEAKGLLKAQDSDFEVVEQLGYDFAGHGEHFMVLIRKSGENTKYVVNELAKACGVKSRDVSWAGLKDRHAVTEQWLSVQLPGKSDPDLTDFVAEHPGIEVLATARHDKKLRPGDLQGNRFTLRITELENCDELNARLEQIAQGGVPNYFGEQRFGHNGNNVVKARAWGNDEFRVRDKSKRSFYLSAARSWMFNQVLSQRIEQGKVSQLMLGDCLLAANDSRPMVVTEITPELEQQVASGELAISAPLLGDNELPTKADAQAFELAIVEQEPALVKLVRDNRMRHERRELLLVPEQMTWQFDENTLTLSFSLPAGAFATAVVRELLDAREPEREFPHD

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP046752_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046752_5

2465238-2465381

Unclear

Consensus_repeat	Method
GTATCCTGCCGAATAGGCAGCTAA	CRISPRCasFinder

2 spacers

cas6f,cas7f

The CRISPR arrays of NZ_CP046752_5

>merge|NZ_CP046752|5|2465238-2465381|CRISPRCasFinder
GTATCCTGCCGAATAGGCAGCTAAAAATATCATTCAAGTGATAGGCTTGAAAATAAAACTGTATCCTGCCGAATAGGCAGCTAAAAATCATTCTAGTTGAGAAAATTTGTCCGTAATCTCGTATCCTGCCGAATAGGCAGCTAA

>NZ_CP046752|5|4|2465238-2465381|CRISPRCasFinder
GTATCCTGCCGAATAGGCAGCTAA	AAATATCATTCAAGTGATAGGCTTGAAAATAAAACT
GTATCCTGCCGAATAGGCAGCTAA	AAATCATTCTAGTTGAGAAAATTTGTCCGTAATCTC
GTATCCTGCCGAATAGGCAGCTAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046752.1\|WP_068945988.1\|2471328_2471604_+\|nitrogen-fixation-protein-NifW	unknown	unknown	gnl\|CDD\|377005
NZ_CP046752.1\|WP_158135889.1\|2450149_2450971_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046752.1\|WP_158135898.1\|2457610_2459836_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|372509
NZ_CP046752.1\|WP_005300301.1\|2471624_2472653_-\|HoxN/HupN/NixA-family-nickel/cobalt-transporter	unknown	unknown	gnl\|CDD\|225911
NZ_CP046752.1\|WP_158135906.1\|2467443_2468217_+\|nuclease	unknown	unknown	gnl\|CDD\|377990
NZ_CP046752.1\|WP_158135912.1\|2474284_2474938_+\|oxygen-insensitive-NAD(P)H-nitroreductase	unknown	unknown	gnl\|CDD\|182929
NZ_CP046752.1\|WP_158135910.1\|2470582_2471221_+\|AcfA-family-outer-membrane-beta-barrel-protein	unknown	unknown	gnl\|CDD\|379226
NZ_CP046752.1\|WP_158135904.1\|2465903_2466332_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046752.1\|WP_115427032.1\|2475013_2475952_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NZ_CP046752.1\|WP_158135891.1\|2451384_2452014_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046752.1\|WP_065170188.1\|2469963_2470431_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379083
NZ_CP046752.1\|WP_158135893.1\|2452684_2453833_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046752.1\|WP_158135908.1\|2468496_2469267_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046752.1\|WP_068945986.1\|2472840_2473878_-\|FUSC-family-protein	unknown	unknown	gnl\|CDD\|224208
NZ_CP046752.1\|WP_158135900.1\|2463463_2464495_+\|type-I-F-CRISPR-associated-protein-Csy3	cas7f	cd09737_cas7f_CAS-I-F	gnl\|CDD\|187868
NZ_CP046752.1\|WP_158135894.1\|2453838_2456088_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379614
NZ_CP046752.1\|WP_158135887.1\|2448481_2449864_+\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|223989
NZ_CP046752.1\|WP_158135896.1\|2456080_2457301_+\|patatin-like-phospholipase-family-protein	unknown	unknown	gnl\|CDD\|366777
NZ_CP046752.1\|WP_158135885.1\|2447942_2448488_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046752.1\|WP_158135902.1\|2464503_2465142_+\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	cas6f	cd09739_cas6f_CAS-I-F:CAS-IV	gnl\|CDD\|187870

Protein	Function_ID	Function_description	E-value
NZ_CP046752.1\|WP_068945988.1\|2471328_2471604_+\|nitrogen-fixation-protein-NifW	gnl\|CDD\|377005	pfam03206, NifW, Nitrogen fixation protein NifW. Nitrogenase is a complex metalloenzyme composed of two proteins designated the Fe-protein and the MoFe-protein. Apart from these two proteins, a number of accessory proteins are essential for the maturation and assembly of nitrogenase. Even though experimental evidence suggests that these accessory proteins are required for nitrogenase activity, the exact roles played by many of these proteins in the functions of nitrogenase are unclear. Using yeast two-hybrid screening it has been shown that NifW can interact with itself as well as NifZ.	1.49398e-05
NZ_CP046752.1\|WP_158135912.1\|2474284_2474938_+\|oxygen-insensitive-NAD(P)H-nitroreductase	gnl\|CDD\|182929	PRK11053, PRK11053, oxygen-insensitive NAD(P)H nitroreductase.	1.90709e-139
NZ_CP046752.1\|WP_158135894.1\|2453838_2456088_+\|hypothetical-protein	gnl\|CDD\|379614	pfam14457, Prok-E2_A, Prokaryotic E2 family A. A member of the E2/UBC superfamily of proteins found in several bacteria. The active site residues are very similar to the eukaryotic E2 proteins. Members of this family are usually fused to E1 and JAB domains C-terminal to the E2 domain. The protein is usually in the gene neighborhood of a gene encoding a distinct metallobetalactamase family protein.	2.88878e-22
NZ_CP046752.1\|WP_005300301.1\|2471624_2472653_-\|HoxN/HupN/NixA-family-nickel/cobalt-transporter	gnl\|CDD\|225911	COG3376, HoxN, High-affinity nickel permease [Inorganic ion transport and metabolism].	3.77321e-137
NZ_CP046752.1\|WP_115427032.1\|2475013_2475952_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.26325e-67
NZ_CP046752.1\|WP_158135910.1\|2470582_2471221_+\|AcfA-family-outer-membrane-beta-barrel-protein	gnl\|CDD\|379226	pfam13505, OMP_b-brl, Outer membrane protein beta-barrel domain. This domain is found in a wide range of outer membrane proteins. This domain assumes a membrane bound beta-barrel fold.	1.25132e-06
NZ_CP046752.1\|WP_158135906.1\|2467443_2468217_+\|nuclease	gnl\|CDD\|377990	pfam08378, NERD, Nuclease-related domain. The nuclease-related domain (NERD) is found in a range of bacterial as well as archaeal and plant proteins. It has distant similarity to endonucleases (hence its name) and its predicted secondary structure is helix - sheet - sheet - sheet - sheet - weak sheet/long loop - helix - sheet - sheet. The majority of NERD-containing proteins are single-domain, but in several cases proteins containing NERD have additional domains which in 75% of cases are involved in DNA processing.	4.49298e-32
NZ_CP046752.1\|WP_158135898.1\|2457610_2459836_+\|AAA-family-ATPase	gnl\|CDD\|372509	pfam13166, AAA_13, AAA domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.	5.08484e-107
NZ_CP046752.1\|WP_068945986.1\|2472840_2473878_-\|FUSC-family-protein	gnl\|CDD\|224208	COG1289, COG1289, Predicted membrane protein [Function unknown].	2.61609e-20
NZ_CP046752.1\|WP_065170188.1\|2469963_2470431_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379083	pfam13239, 2TM, 2TM domain. This short region contains two transmembrane alpha helices that are found associated with a wide range of other domains. This domain may be involved in cell lysis or peptidoglycan turnover.	1.72916e-26
NZ_CP046752.1\|WP_158135887.1\|2448481_2449864_+\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	1.64079e-29
NZ_CP046752.1\|WP_158135896.1\|2456080_2457301_+\|patatin-like-phospholipase-family-protein	gnl\|CDD\|366777	pfam01734, Patatin, Patatin-like phospholipase. This family consists of various patatin glycoproteins from plants. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein but it also has the enzymatic activity of lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have been found also in vertebrates.	9.71901e-13
NZ_CP046752.1\|WP_158135902.1\|2464503_2465142_+\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	gnl\|CDD\|187870	cd09739, Cas6_I-F, CRISPR/Cas system-associated RAMP superfamily protein Cas6f. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6f is an endoribonuclease that generates crRNA; This family is specific for CRISPR/Cas system I-F subtype; Possesses RRM fold; also known as Csy4 family.	6.83575e-48
NZ_CP046752.1\|WP_158135900.1\|2463463_2464495_+\|type-I-F-CRISPR-associated-protein-Csy3	gnl\|CDD\|187868	cd09737, Csy3_I-F, CRISPR/Cas system-associated RAMP superfamily protein Csy3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; predicted Cas7 ortholog.	3.04282e-145

>NZ_CP046752.1|WP_158135902.1|2464503_2465142_+|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4
MTKRYYFLIRFIPAQADYELLAGRCISQMHLFMVNNRQAMNKIGVSFPDWSDATVGQTIAFVAEDKEMMIGLSFQPYFSLMINEGLFEISSICEVSVNALEVRFVRNQTIGKSFLGSKKRRIKRSMARSELFGAGTSLSVTNEERVIDSFHRIPVSSGSSAQDYILFVQKELVGEHVTANFNSYGLATNQERRGTVPELRFCPFFKSYFLEK
>NZ_CP046752.1|WP_158135900.1|2463463_2464495_+|type-I-F-CRISPR-associated-protein-Csy3
MELCTQLNYVRSLSAGKAYFYYLSKSGEMCPLEIDRTRLRAPKGGYAEAYKGGKFVEKNVALQDLAYSNPQFIEECYIKPGVDDIYCAFSLRIRANSLNPDSCNDDEVRSKLSLLAKTYNELNGYQELALRYAKNILLGTWLWRNRACRKLSIEVVTSDSQNLTVENVTRLSWYGHWDKASAECLEKLTAYLMRALSDPTEYFYMDVKAKIGVGWGDEVYPSQEFLDEREGGVPTKQLATVELLTGDETVAFHGQKIGAAIQTIDDWWHEDADKPLRVNEYGADREYVIARRHVAYGNDFYQLVRNTENWIETMAASQTIPNDVHFIMSVLIKGGLFNCSKAK
>NZ_CP046752.1|WP_158135898.1|2457610_2459836_+|AAA-family-ATPase
MFKSIKSIKNFGIFKNTKMNGGQPFLQFNLIYGFNYSGKTTLSRIFRAMQQGYVHEDFATASFAVDRYEQAPVSSDALIPIANLRVFNSDYIKDNVNFVDSSVNPVLIVGERNIELEDELKQLEEVLIPAEKEAWELLKNLAENKDKEKNQRLQNVAKLVNTLSVLGNSKFDIRGVRTLLPQVSSESLKTDKERLQLEETARLQKSDLISNPTISVPNTSALLDQIQTILAESVTRTTIEELEANVGLRKWVEDGVKHHGEATTCQFCKNPLEQVRLDELNAYFSDSYKALSAKINAAIKQVATIKLTYSVPKTTSLYSDLIINFEQLMEKIPQLEEQVEQVKQRLLEVLEDKRNRMEEVVPFSQSDYLMPITSDLIEQLNILIGEHNRRSREHSKEQTAARDAIKRHFVYVETMEYNHAKASEEVVALQKQQGESEGELRRLNDRVMEIKAALRNVKQGADNLNDNLRLYFGKTDIEIQPVGETYQFMREGRPAKHLSDGERTAIAFAYFITELDDESLKDTKPIVYLDDPICSLDSNHIYNVLGIIKDKLNHDKVEQLFISTHNFEFFNLVKTWFDYYKMVKRGDDVKPKRAEFYLVNRKQNASTVEQLPKNLKDHKSEYAYLIAKIKEAVRNPEQFDAVSVQAYVRKILEVYFTFRFNKPFRANNNSFLEQHLLKDIENASTKATTLYEFINERSHAQSISFGVELPDALQAQLQGVWHIIDEAIRTNDKPHYEAYYV
>NZ_CP046752.1|WP_158135896.1|2456080_2457301_+|patatin-like-phospholipase-family-protein
MNRELKKGLALSGGGFRATLYALGSLWRMNEDGLLTELDTITSVSGGSIAAGLLMSKWEELTFEEIDASKGRYRATNFKEVIADPLLTFCSKTITNKSRIILHTLNPKTTAVTEVRKKYETLLFGDSRLCEIPDHDLAPEFIFYGTNLDTGASVRISKREIRDYHIGSASGHDITLAQAVSISSGFPPFLAPIRLCGRNWTWNDSSYSRIPAEQISHFRERLDLCDGGLYDNMGLEMIWKHGKDKEYESVFCCDAGALLPVPWGGWLKAVKSKFGLSLRMTDIMINQQRALRKRTLMRNYFSGEYDGGYWSISSQVKNFKTITPLLSSSEAEQYSHLSKLGTQLESFSDIDNQMLVNLGFCHSDMSIRLNYDKTLTCPSLPFDINNDKDNAIDAVSETNKESPIGI
>NZ_CP046752.1|WP_158135894.1|2453838_2456088_+|hypothetical-protein
MADFFPIEADEIDQNKVKLVGSTAMIKAINKDRNTTLIDVRARVNSSKRAEFISVDICNDDVPSRNSFGICYRERIVYIFTKESELPLTFALRKGFPITMHQNSPSEDAAKSLCLYLEPTDVVAASWTAEKHLKRTNWWLTQAALGKLHHDDQGIEPLFFNPLSTIILPYDYDHELNHGKQLNAVAYNKKDTIEEGAFIVTDWKKKSHSQHGALINVVNITTPSVVHGVVNRNVNTILKFNELLKPLGIEIIDLIRQQLFEIISSSSYRLDVNTTVFILTFPMQRSPDSPVETRQTMAIIAFQSLAELAVMFDVTDETTEYLRINAYGELLPVCSDNIDLKIEFMECLKETSAKDRRLQSGLIKPFGKGALIGAGALGGALVDFWAKAGWGSWTIVDNDSFRPHNFTRHVIPSSAVGQNKAKIVAAHYSYYFQDCNFTGINIDAKNFTLPTVKEYLNNSDLIIDASASLSYPRAISLNRYAPRHMSAFFTPSGSGAVLLVEDKRRRVRLASLEAQYYRVLINEPIGENHLVNTSDQFRSGVSCRDNSFVMSHSRVMACSSLLSEQIIKASCQDAPMIMIWHDDIETGERSSYRAIAHNDVMDNNHSLNKFKVHWDEGIEERIRELRSQNLPNETGGILIGYHDMIQKSVYIVDALPAPDDSVGTPTSFQRGTNGVVAALEEIANRTANNVGYIGEWHSHPKGFSARMSNLDIKQLEELAISLSEDGLPAYQMIVGENETKVYEKVLDSE
>NZ_CP046752.1|WP_158135893.1|2452684_2453833_+|hypothetical-protein
MATVKFYPVGNGDTSLITLKNGKHILMDYRQHSSATDSTTPQFDIASDIKKTLVDAKKDSLEVLAFTHADKDHIEGSTEFFHLEYADKYQGNGRIKIDQLWVPAAMLLESVDQHNLSSELAIWRSEARYRLKNKIGIRVFSQPDELVKLIETWQMNIDDLSDLIVDAGTIVDTFSLENDNVEFFVHSPFMKHCEEAGKEVKKVRNQASLIFNIRFNEGGEVFDFLAIGDSEWEVLEDIVSITKYYKNEDRLRWDLLNIPHHCSYLALSDEKGDNETEPKEKVAELLLLGNKDAYMICSSNSFGESTSEALKSTQPPHLQAKRCYERYLRDVNGRSLIVTMENESKTKPEPVIIEFTSSGLSKRSYRMTAALATAAATPARAG
>NZ_CP046752.1|WP_158135891.1|2451384_2452014_-|hypothetical-protein
MAFNLTYRPLQYPWNNVYFHRALKDPELFAPEKGGDCFLVVQSVCGLHETVNLAAQSLEESWRENDEYIKSGCVGTPPLACHPIYLISIGDGEEEKIVYIGKTSSNSSRFSSGHAAISKLHAPEYDGLSKRLYLCGIVFLKSAKEIPVEWVKPFSRAESLLKSFEANLIYWTQPELNTQHKNFEPIFEYGQVHAQNVTGSTSFWHDKFI
>NZ_CP046752.1|WP_158135889.1|2450149_2450971_-|hypothetical-protein
MRKAFIPVAIIFFLYAYSMVLDPYLKGGFLFMMSTWHEWQTFNAGMIALAAAAISACVMIQVDRNTHRRHNELIDSNKRIAEEQRVRNFVAAKSFLPHALTDIYNYVEECSKILIDIYVMFNHKQIQLIEDENKKDFTNYFKYLNKPENYQMAFKECISLGNEEQSKQLSEILITLQIFISRMRRLENGENISRSYSIEMLVNSVYFGLRLNGLYDFARSGERIHHPQNKSENYYTRISTLSDNFHFEPDNDEEIDKYIGVYSRKDGCDNSQK
>NZ_CP046752.1|WP_158135887.1|2448481_2449864_+|DEAD/DEAH-box-helicase-family-protein
MLRVWQAECVDLAINKFLSNRRPHFFCQATPGAGKTVMAAEVAKRLFQEGMIDLVLCFSPSLSVAEGMKKTFSWKLECSFNGGLGSLGGSYTYQSIRFLDENFWSNVSKYRALVVFDEIHHCSFDEDGRSNSWGLEIVTKIQDFARYTLALSGTPWRSDRLPIVMAEYSDPDGKVVCDYQYGLQQAVVDGVCRQPKIVLIDNEHLSIQTGNSNQHFASILECLKQSDVSYQSVIHNEDAINYILNSGCQKLAQIRQLSPNAGGLVVAASIKHAKHIQKRLVEHFNQSACIVTYHHDNPLNEIESFRHSNVQWIVSVGMISEGTDIPRLQVCCHMSSVKTELYFRQVLGRILRVNDSPNQEAWLYTFAEESLIGFAERIEQDIPDSCMYIKQVNNVPSDIDEKRLSPSTVSESVQSNRPQQSLLSWREISDVINQNNAGCTLALDELRLGQFKQRVIAAFT
>NZ_CP046752.1|WP_158135885.1|2447942_2448488_+|hypothetical-protein
MNKVTRINPDMFNLLIENEMDNFSVIEARDALLNGTSTFPSRDDARKYVYRQLLSFEEKGWLSVTGTRRDKIFHQTNKFKSLTIEPRTSRKRKASYGPMTGQVLDYSLNTLEQEKKQHEGELAITLGEIEEYQSLLIRFPNSKQDIQPLFNIARERSAKLLGRINALTNWMKVAQSKSLQC
>NZ_CP046752.1|WP_158135904.1|2465903_2466332_+|hypothetical-protein
MTASQNHKYNQLKWLYSALSGFCAAYFLAFFSGSQSIEQSPYLLISTLLFSVCLPIFTAFAIAHVYMSESDLAVEQCDRALNLRWVKWLTIWAFSLLYFAVWFLAAFFSFWVVVAFTIASASCFFIFVFFIRRLHSLSMAKS
>NZ_CP046752.1|WP_158135906.1|2467443_2468217_+|nuclease
MNIFEVFINILEQVWYLLPLLLIVSVFKSRWLKGIFGEYLVNRLLSKLPESDYTLIKDVTLPTSNGTTQVDHIVVSKYGIFVVETKNMKGWIFGSARQKLWTQKIYRHSSKFQNPLHQNYKHIKALETLLGCSADYLHSVIVFIGDSTFKTEMPPNVTYARGSIRYIQQFNKVVFSDKDYARLTDSINQIKLKRGVITDLKHRNHVKEIVASKVSSNQCPRCCSEMVLRETKRGENIGKQFWGCSTFPKCRVVKQLN
>NZ_CP046752.1|WP_158135908.1|2468496_2469267_-|hypothetical-protein
MKNQYILKLVIYCLLLSIVGIATLYVFSVYVEDQIFSEIGKAVSISLITAAFFTIVINFFQRNHFEEKLSDVLEHHVPFMNKLNKVGITSFERSFPLQSDEYETSFIESNTITLVFNDGKRFYQNNSTLFRKRFSQSGKTTRFVFMDPKASDSIAVLTRKNGHKGNYYSDKISQFIDYLKEESKEEDHNIEIYVHDLFTTMSVVLTEQYAMFSLYRIAPGQEAVPHITVQKNSFELCEYDKIAKDVQKLVEHSTKA
>NZ_CP046752.1|WP_065170188.1|2469963_2470431_+|helix-turn-helix-domain-containing-protein
MIIRKLRLQRGWSQEQLSQLSGVSVRTIQRIEKGQNAGLESLKSLAAVFEVNVEHLQKEPEMNSDSLLTLEEKQVLAQVQEIKSFYQNLLSYVCVIAMLFAINLWTDPSYIWAWWPAMGWGIGIVIHGINAFKVFNLFSPEWERKQVEKRLGRKL
>NZ_CP046752.1|WP_158135910.1|2470582_2471221_+|AcfA-family-outer-membrane-beta-barrel-protein
MKKHLLAALLCTSSSAMAAPYVGLDLGLSTFSHDYQTYFSADNKAVSPDDSGMVLNGYVGYRWDAFGLELGYRHFDELDGSSSQFMGNVDGFRHEREWDADLKVSQITLKPVYFYALTDRVELKTGLGLTYTQYDYRSDSSDEYELITNDDIEHNVNRAGGENKKNNEFGVIASVGVDYRIWQQLHIGAGVDYYADSQANAATFMLTSRYQF
>NZ_CP046752.1|WP_068945988.1|2471328_2471604_+|nitrogen-fixation-protein-NifW
MSQTDIQQKIASFTSIEQALEYFEIEFDSRFIDEYRIPLMKRFNGYLLIQKPDDWFSARRALKNAYCKIQRGRLDPHTRSACRGCTSCQRR
>NZ_CP046752.1|WP_005300301.1|2471624_2472653_-|HoxN/HupN/NixA-family-nickel/cobalt-transporter
MKISHTTQKHAIWLISSLIVVNVVVWITAIFAFYQRPGMLGMSLLAWSLGLRHAVDADHIAAIDTTTRKMMEQGKEPIAIGTFFSLGHSTIVMLAATAIAVTVGTFKDKIPYISNIGGTIGTSVSILFLLIMAYINLTIFISVYKKFNLYKKNQQIDKTELDIQLSGPLNKLFHFSFKFINKSWHMYFVGFLFGLGFDTATEITLLALSATNASQGMDIWLIMIFPILFTAGMSLIDTLDNLVMVGAYGWAFSKPSRKLYYNMTITGVSVIVALMIGGLEALSALASSLQLQGPIWDSINNMTDHFGMVGIAVVITFIACWLISIANYKIKGYDKLDAPLAE
>NZ_CP046752.1|WP_068945986.1|2472840_2473878_-|FUSC-family-protein
MKNLNKTIIKNIRLFNMLRILISCVIAYTIAMFFHIPYIAWAPITIIVVMAANYSGAISHKASQRISGTFLGALLGLSLYLLPETDKILHYTLLLSMLAVTLFFTLGKYSYGAILASVTLVLVAGNGPGDLTIALWRTVNVLWGGLLAILASKFLFPARASYHFKILSGDYLEQFHLVYSQHNQLAHQQEEHEPINLAPLNATLKQLSGLEGSIKHETPNQGNCTKKLIQCYERMFSLLENITQTPWSHQYGHRKIQELDGLFEAKEQLSSCIETLAEHISSEAVLPYVLQQKDLEILALFPTIAGSKEPRTDISFYSYLWLNRELARKLVMVTEYIEAESKLSK
>NZ_CP046752.1|WP_158135912.1|2474284_2474938_+|oxygen-insensitive-NAD(P)H-nitroreductase
MSIVSAAEARYSTKAFDASRKLTDKQVADLKELVRVSASSVNSQPWHFILASTDEGKAKIAKSMQGPYVFNERKALDASHVLVFCAKTDIDEQYLLELLDSEDKAGRFANEEAKQGMHTGRSFFVNMHLEQLHDVQAWMEKQVYLNVGTLLLGAAAMDIDAVPIEGFDADVLDAEFGLKEKGFKSLVVVPLGFHSEEDFNAKLPKSRWEETRVFTEC
>NZ_CP046752.1|WP_115427032.1|2475013_2475952_-|LysR-family-transcriptional-regulator
MKALNDLQVFIEASRMGSFSKVANSMGITPAAVSAAIKRLEEQVGFPLFIRSTRHLRLTNEGEIFCDKASMAVNILQDGLDQIANDRNAFSGKLHITAPSDFGRNLLLTWIAEFQEIYPDITIKLELSDKVADIYSQPVDIAIRYGQPADSNLVAISLCQLNEGITCATPEYIAANPTITEPMDLLAHNCLCFMVADTLYNKWQFSCDNRSEIVHVSGNMTGNDSDMIHRLALKGKGIIHTSLMDLSEDIIAGRLVPIFPQWRGFSAPLYMVCADRRLLNPTIRKFQEFIKEKCCQQRQRVLTALGNEQVTD

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

2808298 : 2875833

Vibrio_phage(20.0%)

transposase,protease,tRNA,holin

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_158136068.1\|2808298_2809699_-\|tRNA	asparagine--tRNA ligase	A0A2K9V902	Bandra_megavirus	1.9e-87	38.4
WP_005299831.1\|2809922_2810591_-	7-carboxy-7-deazaguanine synthase QueE	A0A1B0Z0A9	Vibrio_phage	8.0e-12	30.1
WP_158136070.1\|2810820_2812035_+	ROK family protein	NA	NA	NA	NA
WP_158136072.1\|2812452_2813856_+	AAA family ATPase	NA	NA	NA	NA
WP_158136074.1\|2813848_2814403_+	hypothetical protein	NA	NA	NA	NA
WP_068945851.1\|2814504_2815407_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_005299826.1\|2815632_2816382_-	lactate utilization protein C	NA	NA	NA	NA
WP_036764035.1\|2816396_2817812_-	iron-sulfur cluster-binding protein	NA	NA	NA	NA
WP_036764032.1\|2817823_2818543_-	(Fe-S)-binding protein	NA	NA	NA	NA
WP_158136076.1\|2818724_2820308_-	L-lactate permease	NA	NA	NA	NA
WP_005299820.1\|2820997_2821564_-\|protease	ATP-dependent protease	NA	NA	NA	NA
WP_109375107.1\|2821635_2822913_-	adenosylmethionine--8-amino-7-oxononanoate transaminase	A0A1V0SKB7	Klosneuvirus	3.0e-23	29.1
WP_158136078.1\|2823096_2824149_+	biotin synthase BioB	NA	NA	NA	NA
WP_158136080.1\|2824132_2825326_+	8-amino-7-oxononanoate synthase	NA	NA	NA	NA
WP_158136434.1\|2825327_2826185_+	malonyl-ACP O-methyltransferase BioC	A0A1X9I669	Streptococcus_phage	1.7e-06	21.1
WP_005299809.1\|2826177_2826861_+	ATP-dependent dethiobiotin synthetase BioD	NA	NA	NA	NA
WP_158136082.1\|2827555_2828437_+\|protease	protease HtpX	NA	NA	NA	NA
WP_005299805.1\|2828600_2829815_-	MFS transporter	NA	NA	NA	NA
WP_044175811.1\|2829814_2829994_-	hypothetical protein	NA	NA	NA	NA
WP_050787766.1\|2830263_2830662_-	hypothetical protein	NA	NA	NA	NA
WP_158136084.1\|2831015_2832917_+	MFS transporter	NA	NA	NA	NA
WP_158136086.1\|2833060_2834020_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_158136088.1\|2834012_2834939_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	7.2e-19	27.7
WP_005299795.1\|2834938_2836036_+	ABC transporter permease	NA	NA	NA	NA
WP_106142497.1\|2836505_2837360_+	hypothetical protein	NA	NA	NA	NA
WP_044175803.1\|2837439_2837973_-	dihydrofolate reductase	NA	NA	NA	NA
WP_158136090.1\|2838310_2839240_-	nucleotide-binding protein	NA	NA	NA	NA
WP_158136092.1\|2839817_2840675_+	DUF2806 domain-containing protein	NA	NA	NA	NA
WP_158136094.1\|2840741_2841353_+	hypothetical protein	NA	NA	NA	NA
WP_106338650.1\|2841488_2842064_+	hypothetical protein	NA	NA	NA	NA
WP_158136096.1\|2842108_2842966_+	DUF2971 domain-containing protein	J9Q7Y9	Salmonella_phage	1.6e-12	28.3
WP_081327331.1\|2843104_2844139_+\|transposase	IS630 family transposase	M4M9P8	Vibrio_phage	6.0e-14	78.3
WP_065172387.1\|2844318_2844567_-	DUF3297 family protein	NA	NA	NA	NA
WP_158136098.1\|2844692_2845865_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_068969545.1\|2845961_2846975_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_158136100.1\|2847363_2849304_+	FUSC family protein	NA	NA	NA	NA
WP_106261705.1\|2849385_2850228_-	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_158136102.1\|2850227_2851925_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	5.2e-15	26.2
WP_005299771.1\|2851927_2852479_-	ECF-type riboflavin transporter substrate-binding protein	NA	NA	NA	NA
WP_005299769.1\|2853220_2853865_+	UvrY/SirA/GacA family response regulator transcription factor	NA	NA	NA	NA
WP_081313193.1\|2853864_2855718_+	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_036764014.1\|2855834_2856395_+	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_158136104.1\|2858483_2858807_-\|transposase	transposase	NA	NA	NA	NA
WP_158136106.1\|2859061_2859484_-\|transposase	transposase	NA	NA	NA	NA
WP_158136108.1\|2860374_2861637_+	hypothetical protein	NA	NA	NA	NA
WP_106260080.1\|2861640_2862123_+	hypothetical protein	NA	NA	NA	NA
WP_158136110.1\|2862119_2864081_+	DUF3732 domain-containing protein	NA	NA	NA	NA
WP_158136112.1\|2864927_2865830_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_158136114.1\|2865970_2867605_+	MFS transporter	NA	NA	NA	NA
WP_068946788.1\|2867620_2868742_+	linear amide C-N hydrolase	NA	NA	NA	NA
WP_158136116.1\|2868962_2869484_+	hypothetical protein	NA	NA	NA	NA
WP_158136118.1\|2869540_2870350_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_136039755.1\|2870540_2871260_+	hypothetical protein	NA	NA	NA	NA
WP_158136120.1\|2871910_2873593_+	wax ester/triacylglycerol synthase family O-acyltransferase	NA	NA	NA	NA
WP_044175524.1\|2873726_2873993_-	acyl-CoA-binding protein	A0A0M3SGU0	Mollivirus	3.4e-06	46.6
WP_158136122.1\|2874201_2875833_+\|holin	choline dehydrogenase	A0A1V0SI18	Klosneuvirus	5.8e-72	35.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP046751

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP046752

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection