CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP046628	Streptococcus equinus strain CNU 77-23 chromosome, complete genome	2 crisprs	cas3,DEDDh,WYL,csa3,DinG,cas9,cas1,cas2,csn2	0	20	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046628_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046628_1

1243451-1243952

TypeII

II-A:II-A,II-B

Consensus_repeat	Method
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	PILER-CR
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CRISPRCasFinder
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CRT

7 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP046628_1

>merge|NZ_CP046628|1|1243451-1243952|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACGAATTTGAAGAAGACCATTGTTATGCCGTCGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTTTAGGTACAGTCTCAATAGTAATCCAGCCGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACAATAAAGCAGAGTACCAAATAGATTACAGTGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTCACTTTATATGGATAAGCGTGCTCTAGATGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTAAATAGGAACGGTTTTTCTATTGACTTAAAGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTAAATAGGAACGGTTTTTCTATTGACTTAAAGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACCACCGCCATTGACATAGAAAAGGAGGCTCCAGTTTTAGAGCTGTGCTGTTTCGAAAAATTCTCTAACT

>NZ_CP046628|1|1|1243451-1243884|PILER-CR
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GAATTTGAAGAAGACCATTGTTATGCCGTC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TTTAGGTACAGTCTCAATAGTAATCCAGCC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AATAAAGCAGAGTACCAAATAGATTACAGT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TCACTTTATATGGATAAGCGTGCTCTAGAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TAAATAGGAACGGTTTTTCTATTGACTTAAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TAAATAGGAACGGTTTTTCTATTGACTTAAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC

>NZ_CP046628|1|1|1243451-1243952|CRISPRCasFinder
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GAATTTGAAGAAGACCATTGTTATGCCGTC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TTTAGGTACAGTCTCAATAGTAATCCAGCC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AATAAAGCAGAGTACCAAATAGATTACAGT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TCACTTTATATGGATAAGCGTGCTCTAGAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TAAATAGGAACGGTTTTTCTATTGACTTAAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TAAATAGGAACGGTTTTTCTATTGACTTAAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CACCGCCATTGACATAGAAAAGGAGGCTCCA
GTTTTAGAGCTGTGCTGTTTCGAAAAATTCTCTAACT

>NZ_CP046628|1|1|1243451-1243951|CRT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	GAATTTGAAGAAGACCATTGTTATGCCGTC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TTTAGGTACAGTCTCAATAGTAATCCAGCC
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	AATAAAGCAGAGTACCAAATAGATTACAGT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TCACTTTATATGGATAAGCGTGCTCTAGAT
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TAAATAGGAACGGTTTTTCTATTGACTTAAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TAAATAGGAACGGTTTTTCTATTGACTTAAA
GTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CACCGCCATTGACATAGAAAAGGAGGCTCCA
GTTTTAGAGCTGTGCTGTTTCGAAAAATTCTCTAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046628.1\|WP_021142653.1\|1249423_1249900_+\|shikimate-kinase	unknown	unknown	gnl\|CDD\|234654
NZ_CP046628.1\|WP_157339388.1\|1240772_1241639_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP046628.1\|WP_157339387.1\|1236639_1240773_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_CP046628.1\|WP_039691771.1\|1249896_1250721_+\|prephenate-dehydratase	unknown	unknown	gnl\|CDD\|237013
NZ_CP046628.1\|WP_157339389.1\|1241635_1241980_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP046628.1\|WP_004232469.1\|1244052_1244469_+\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|179085
NZ_CP046628.1\|WP_157339386.1\|1235550_1236210_+\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
NZ_CP046628.1\|WP_157339395.1\|1252453_1253824_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|225174
NZ_CP046628.1\|WP_157339392.1\|1246178_1248014_+\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_CP046628.1\|WP_157339391.1\|1242927_1243308_+\|HicB-family-protein	unknown	unknown	gnl\|CDD\|374224
NZ_CP046628.1\|WP_157339396.1\|1255429_1256608_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP046628.1\|WP_157339390.1\|1242728_1242914_+\|addiction-module-toxin,-HicA-family	unknown	unknown	gnl\|CDD\|377942
NZ_CP046628.1\|WP_033153705.1\|1254280_1255372_+\|transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP046628.1\|WP_157339397.1\|1256862_1257627_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP046628.1\|WP_027968563.1\|1234787_1235561_+\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_CP046628.1\|WP_157339393.1\|1248147_1249431_+\|3-phosphoshikimate-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|235037
NZ_CP046628.1\|WP_021142663.1\|1233986_1234715_+\|acyl-ACP-thioesterase	unknown	unknown	gnl\|CDD\|366738
NZ_CP046628.1\|WP_157339702.1\|1241969_1242632_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_CP046628.1\|WP_134775434.1\|1236206_1236377_+\|NADH-quinone-oxidoreductase-subunit-L	unknown	unknown	unknown
NZ_CP046628.1\|WP_157339394.1\|1250871_1252341_+\|LytR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224235

Protein	Function_ID	Function_description	E-value
NZ_CP046628.1\|WP_021142653.1\|1249423_1249900_+\|shikimate-kinase	gnl\|CDD\|234654	PRK00131, aroK, shikimate kinase; Reviewed.	1.13515e-61
NZ_CP046628.1\|WP_157339388.1\|1240772_1241639_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	9.32211e-129
NZ_CP046628.1\|WP_157339387.1\|1236639_1240773_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP046628.1\|WP_039691771.1\|1249896_1250721_+\|prephenate-dehydratase	gnl\|CDD\|237013	PRK11898, PRK11898, prephenate dehydratase; Provisional.	5.44614e-149
NZ_CP046628.1\|WP_004232469.1\|1244052_1244469_+\|nucleoside-diphosphate-kinase	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	5.89419e-80
NZ_CP046628.1\|WP_157339386.1\|1235550_1236210_+\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	9.62471e-60
NZ_CP046628.1\|WP_157339395.1\|1252453_1253824_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	0
NZ_CP046628.1\|WP_157339392.1\|1246178_1248014_+\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_CP046628.1\|WP_157339391.1\|1242927_1243308_+\|HicB-family-protein	gnl\|CDD\|374224	pfam15919, HicB_lk_antitox, HicB_like antitoxin of bacterial toxin-antitoxin system. This is a family of HicB-like antitoxins.	1.21448e-15
NZ_CP046628.1\|WP_157339396.1\|1255429_1256608_+\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.32284e-39
NZ_CP046628.1\|WP_157339390.1\|1242728_1242914_+\|addiction-module-toxin,-HicA-family	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	5.25785e-13
NZ_CP046628.1\|WP_033153705.1\|1254280_1255372_+\|transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.39325e-06
NZ_CP046628.1\|WP_157339397.1\|1256862_1257627_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	3.04115e-12
NZ_CP046628.1\|WP_027968563.1\|1234787_1235561_+\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.66444e-129
NZ_CP046628.1\|WP_157339393.1\|1248147_1249431_+\|3-phosphoshikimate-1-carboxyvinyltransferase	gnl\|CDD\|235037	PRK02427, PRK02427, 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional.	0
NZ_CP046628.1\|WP_021142663.1\|1233986_1234715_+\|acyl-ACP-thioesterase	gnl\|CDD\|366738	pfam01643, Acyl-ACP_TE, Acyl-ACP thioesterase. This family consists of various acyl-acyl carrier protein (ACP) thioesterases (TE) these terminate fatty acyl group extension via hydrolysing an acyl group on a fatty acid.	1.39377e-93
NZ_CP046628.1\|WP_157339702.1\|1241969_1242632_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	2.56242e-116
NZ_CP046628.1\|WP_157339389.1\|1241635_1241980_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	5.89226e-48
NZ_CP046628.1\|WP_157339394.1\|1250871_1252341_+\|LytR-family-transcriptional-regulator	gnl\|CDD\|224235	COG1316, LytR, Transcriptional regulator [Transcription].	7.43333e-54

>NZ_CP046628.1|WP_157339391.1|1242927_1243308_+|HicB-family-protein
MLKTYPAIFHKEEGGSFWVEFPGFGGGTEGKDIEEAMKNAREMLDSSLAAYLDEGLALPKVIDMSELTVDDGFITLIQADPSPYLKKTKAIRKNVTVPEWLVRLADREQVNYSEVLTKALEKKLQL
>NZ_CP046628.1|WP_157339390.1|1242728_1242914_+|addiction-module-toxin,-HicA-family
MPKTVKELAKIAISKGWKEVRVKGSHHQFKKDGKAYIVTIPIHGNKVVGAGLERKNLKDLD
>NZ_CP046628.1|WP_157339702.1|1241969_1242632_+|type-II-A-CRISPR-associated-protein-Csn2
MKINFPILDEPLEISGGTILAVENVAVFSNLVRQLYSYTEESELKLFDKKLKSLKESELLLVTDILGFDVNSSSMLKLIHADLESQLNEKPEVKSMIENLADTITELIAYECLENELDLEYDEITVLELIKALGVKIETQSDTIFEKCFEILQIYNYLSKKKLLIFVNSGAYLTQNEMERLMEYIKLSNQKVLFLEPRKLYDFPQYVLDNDYFLIAENMS
>NZ_CP046628.1|WP_157339389.1|1241635_1241980_+|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTETVEERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNNSANKAMIDRLQANNPKKGSITLLTVTEKQFARMIYLNGERDTSVANSDKRLVFLGEDYSDED
>NZ_CP046628.1|WP_157339388.1|1240772_1241639_+|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTVIVNEHSKLSYKNNHLIFKDAYHTEMIHLEEIDILLLETTNIVLTTMLIERLVDKNILIIFCDEKRLPTAMLTPYYGRHDSSLQLTNQIAWDDDVKCDVWTNIIAQKILNQSMYLGECSFFEKSQSIMDLYHGLEPFDPSNREGHSARIYFNTLFGNDFSREQDNDINAGLDYGYTLLLSMFARELVVCGCMTQLGLKHSNQFNQFNLASDIMEPFRPIVDRIVYENRNASFVKIKRELFTMFDETYSYNNKEMYLNNIVSDYTKKVVKALNHNGKGVPEFRI
>NZ_CP046628.1|WP_157339387.1|1236639_1240773_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKKSYSIGLDIGTNSVGWSVITDDYKVPAKKLKVLGNTDKKYIKKNLLGALLFDSGETAEATRLKRTARRRYTRRKNRLRYLQEIFGKEMAKVDESFFQRLEESFLTDDDKTFDSHPIFGNKVEEDAYHQEFPTIYHLRKHLADSPEKADLRLVYLALAHMIKFRGHFLIEGQLDAENTDVQKLFNDFVETYDKIADESHLSEVEVDASSILTNKISKSRRLENLIKQYPTEKKNTLFGNLVALALGLQPNFKTNFKLSEDAKLQFSKDTYDEDLEELLGKIGDDYADLFTAAKNLYDAILLSGILTVDDNSTKAPLSASMIKRYEEHHEDLEKLKTFIKVNNSDKYHEIFKDKSKNGYAGYIENGVKQDIFYKHLKSIISEKNGGQYFLDKIEREDFLRKQRTFDNGSIPHQIHLQEMRAILRRQGEYYPFLKENQAKIEKILTFRIPYYVGPLARKNSRFAWAKYHSDEPITPWNLDEVVDKEKSAEKFITRMTLNDLYLPEEKVLPKHSHVYETFAVYNELTKIKYVNEQGKSFFFDANMKQEIFDYVFKENRKVTKAKLLSYLNNEFEEFRINDLIGLDKDSKSFNASLGTYHDLKKILDKSFLDDKTNEQIIEDIVLTLTLFEDRDMIHERLQKYSEIFTSQQLKKLERRHYTGWGRLSYKLINGIRNKENNKTILDFLIDDGHANRNFMQLINDDSLSFKTIIQEAQVIGDVDDIEAVVHDLPGSPAIKKGILQSVKIVDELVKVMGHNPQNIVIEMARENQITGYGRNKSNQRLKRLQDSLKEFGSDILSKKKPSYIDSKVENSHLQNDRLFLYYIQNGKDMYTGEELDIDHLSDYDIDHIIPQAFIKDNSIDNRVLTSSAKNRGKSDDVPSIEIVRNRKSYWYKLYKSGLISKRKFDNLTKAERGGLTEADKAGFIKRQLVETRQITKHVAQILDARFNTKRDENDKVIRDVKVITLKSSLVSQFRKEFKFYKVREINDYHHAHDAYLNAVVGTALLKKYPKLAPEFVYGEYKKYDVRKLVAKSSDNHSELGKATAKYFFYSNLMNFFKTEVKYADGRVFERPDIETNADGEVVWNKRRDFDIVRKVLSYPQVNIVKKVEVQTGGFSKESILPKGDSDKLIPRKTKKFQWETQKYGGFDSPTVAYSVLVVADVEKGKTRKLKTVKELVGISIMERSSFEENPVSFLEKKEYHNVQEDKLIKLPKYSLFEFEGGRRRLLASAIELQKGNEVVLPQYMVNLLYHSQHVNNSHKPEHLNYVKQHKDEFKDIFNLIISIARINILKPKVVDNLINEFTEYGQEDISSLSESFINLLKFTSFGAPGAFKFLKLDVKQSNLRYQTVTEILNATLIHQSVTGLYETRIDLSKLGEE
>NZ_CP046628.1|WP_134775434.1|1236206_1236377_+|NADH-quinone-oxidoreductase-subunit-L
MTFAWYFWLLFAVAWIFAITFWVKSSNISQKWLRITYVICGIIAFLLPFFWGWLVS
>NZ_CP046628.1|WP_157339386.1|1235550_1236210_+|TIGR01906-family-membrane-protein
MKTKIWTFSTWLWLLSLAVLVAIYGAWLIYPLEIDWLKLSLQVTITKDELLKNFNILMTYLTNPLSHKLAMPDFSSSASGLKHFRDVKHLFHLAQAVFVILLYPSWRFLKNSRAKKSLFLHQRTFTFAAFLPIVIAVAGLLIGFDQFFTLFHEALFPGDSSWLFNPATDPIIWVLPEEYFMHCFIIFFVAYEVMMLSLVATARKQLNHRLKNNERKDEK
>NZ_CP046628.1|WP_027968563.1|1234787_1235561_+|TIGR01457-family-HAD-type-hydrolase
MTYKGYLIDLDGTIYKGKDRIPAGERFIQRLQERNIPYVLVTNNSTRTPEKVQEMLSTQFNVHTPLETIYTATMATIDYMNDLNRGKTVYVIGETGLKTAIAEAGYVEDTENPAYVVVGLDNDLTYEKLAVATLAIQKGAVFIGTNPDLNIPTERGLMPGAGAINKLLEAATRVQPVFIGKPNAIIMNKALDVLGVKREEAIMVGDNYLTDIMAGIQNDIATLLVTTGFTKPEEVPTLPVKPNHVLASLDEWNFDEN
>NZ_CP046628.1|WP_021142663.1|1233986_1234715_+|acyl-ACP-thioesterase
MGLSYREKYQVPFYESDINQNMKLSQLLSLVLQVSGKQSLSLGMSDEHIYKTYNLVWIITEYAIEIERLPKYTENIVIETVPTAYNKLFCYRDFNVYSESGEKLLTIHSTFVLMDYDTRKVHPVLDEIVEVYQVEKVKKFFRGPRYEGLENPEETLYHVRFFDLDLNGHVNNSKYLEWMYDVLDVKFLEEYIPHRINLKYVKEVHYGHDIKSRVERVGLTTKHEIVTQGAVRAQALIEWMEK
>NZ_CP046628.1|WP_004232469.1|1244052_1244469_+|nucleoside-diphosphate-kinase
MEKTFFMIKPDGVKRGLVGEVLKRIERRGFKIEKLEMRMATPELLEKHYEDLVDRPFFPLIVDFMTSGPVIAGVMSGEEVITSWRTMMGATNPKEALPGTIRGDFAQAPAEGAATFNIVHGSDSPESVEREIALWFGE
>NZ_CP046628.1|WP_157339392.1|1246178_1248014_+|elongation-factor-4
MDIQELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFSYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVIGLDASEAVLASAKAGIGIEEILEQIVEYVPAPAGDVEAPLQALIFDSVYDAYRGVILQVRIVNGMVKPGDTIQLMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYIAASIKTVADTRVGDTVTLAENPAEAPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGDMLEVSNPSEFPDPTKVASIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDENRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYEISEYRKSKLVKMDILLNGDKVDALSFIVHNEFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDESSKK
>NZ_CP046628.1|WP_157339393.1|1248147_1249431_+|3-phosphoshikimate-1-carboxyvinyltransferase
MKLLTNVSQLQGTLRVPGDKSISHRSIMFGSLAKGKTTVRDILRGEDVLSTMQVFRDLGVDIQDDGELVTITGVGFDGLKAPKNKLNMGNSGTSIRLISGVLAGQDFTVEMFGDDSLSKRPMDRVTIPLRQMGVEVSGQTERDLPPLTMHGSKALKPIHYQLPVASAQVKSALIFAALQADGESVIIEKEKTRNHTEDMIVQFGGKIDVNGKEIRIKGGQEFTGQDVVVPGDISSAAFWLVAGLIVPNAKVTLKNVGINETRTGILDVIKAMGGKMTISDVDDIAKSATIIVETSELHGTEIGGEIIPRLIDELPIIALLATQANGTTVIRDAEELKVKETDRIQVVADALNAMGADITPTDDGMIIKGKTPLHGAKINTFGDHRIGMMTAIAALLVSHGDVELERAEAINTSYPSFFNDLEVLSRG
>NZ_CP046628.1|WP_021142653.1|1249423_1249900_+|shikimate-kinase
MARIIIGFMGSGKSTISSLLDKDYVDMDALITERIGMSIADFFEKEGEAKFREIESQVLAELVNSEHVISTGGGVVINPINRDILAKNGETIYLKADFDTLYDRIKNDTKNVRPLFINNSKEAFKAIFDGRREMYESAANRIIEVAGKTPEEIVEEIG
>NZ_CP046628.1|WP_039691771.1|1249896_1250721_+|prephenate-dehydratase
MKVGYLGPSGSFTHNVAVKAFPDDERMPFANITEVIKSYEEGVVDYAIIPVENSIEGSVHETLDYLYHQANIEAVAEMIQPIKQQLLATSQDKKIEKIFSHPQAIAQGKKYIKAHYPNAQIEMTASTAYAARYIAENPDEPYAAIAPAAAAKEYGLVIIAKDIQEMDENYTRFWLLGRQKPVFDLPKSQQKLSLAITLQDNLPGALYKALSVFAWRGINLTKIESRPLKTALGEYFFIVDVDNSNEALVACALEELQLLGIDYKTLGNYDVYKL
>NZ_CP046628.1|WP_157339394.1|1250871_1252341_+|LytR-family-transcriptional-regulator
MANNRLSRHEELRYQYLLGNLEYLNAQQKEEFDYLYQKKLMSMQQPSNYSSSAYNETCDDQYDDYGYYDDYNNDYYDDYEDSAAYVDYDDYSGYDSYDDQVTSQGLPKYPKFEKVSRPKRKHQKKPKKSSYLDYYEGIDDKPVKKVKKSKKKKRKKRLKHFLQFFAMLIVLVMAGMIYMFFHGVKEVSSGETNYSAAVTEPFNGQDSKDGTNILILGSDKRISQGSSDARTDTIMVLNIGNKEGKVKLVSFMRDTLVNINGVSYNDYANDQKLNVAFNIGEQDESQGAELMRKTLKDNFDINIKYYVMVDFETFAEAINTLFPNGVDIDAKFGTVDGQEVSSVEVPDDLNMQPDGTVPNQTIEVGEQKMDGRTLLNYARFRKDDDGDYGRTQRQQQVISAIVSQIKDPSKLFTGSAAIGKIYALTSTNVSYPFLVKEGLGVVTSGKKGIEQKTIPEEGDWTDDYDMYGGLGISIDFNKYQEELKELGLR
>NZ_CP046628.1|WP_157339395.1|1252453_1253824_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MLEKNSIVEVEITDLSHEGAGVAKVDGFVFFVENALPGEKIKMRVLKVKKNIGFGKVEEYLTISEHRNQDLNVDYLRTGIADFGHLAYSEQLKFKRKQVADNLYKTAGISDVEVAETLGMEHPYAYRNKAQVPVRRVNGQLETGFFRKHSHDLMPISDFYIQNKEIDRLINFTRDLLRRFDLKPYDEKEQTGLIRNLVVRRGHYSGEMMLVFVTTRPKIFRIEQIIEKIVAEFPAVKSIVQNINDKNTNAIFGNDFRTLYGKDTIVDSMLGNQYEISARSFYQVNTEMAEKLYQTAIDFSDLTADDIVIDAYSGIGTIGLSFAKNVKAVYGVEVIEEAVEDAKRNAALNGITNAHYVADSAEHAMATWSKNGIKPSVILVDPPRKGLTENFIKASVAMQPEKVTYISCNPATMARDIKIYQELGYKLQKVQPVDLFPNTHHVEAVSLLVRATETAK
>NZ_CP046628.1|WP_033153705.1|1254280_1255372_+|transporter
MSKRIFNLYVMNIFLSGLPYYFVTMLLLKHLGFSFTEIASLSVITELCGSVFDIPLSVISSKFGYKKILVISNFLLILALSCLLFGKSNIIYISAISFGLSESLSSGVLNAYNFEIIDDEVVYKSFLKYLNTIKYVFIAIVTIISPYLLNRNFSYPIIISIVFVVLSQLSLIGLPEIRNTLNNDQKIFSIDNVKDIPWNLILLGVAFSTLIMISNSYAGIFLNEQGLSLDMLGIVLFMFNISMALGSYLKIKFKISLMLPILAIFMFFQTNLFIQIITFLLMRILNSSYNNHFYSKFNMSIEKNRAVSWSVYNLFISISFMVADFLGGIFADNFSIRSNYLIFGTVSLFCLVFFSFSNREKRT
>NZ_CP046628.1|WP_157339396.1|1255429_1256608_+|MFS-transporter
MSNSFIKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVPILIGISSFVASILVPLVTKRLALNKVLSLSQFGKTILLLILVGMFIVMKSVPPLVMYLFVVVISILDGFAAPVSYAIVPRYATDLGKANSALSMSGEATQLVGWGLGGLLFATIGLLSTTLIILLLYIISSFMMLFLPDAEVEVLESETNLDILVKGWKSVARDPRLRLFISANLFEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIITSGLIAFRLSEKFLAAKWKSILFPLVSIAIVTLAIILFPNAQMFLFFSALVGMLSQLKEVPESVFLQETVEENNLVNVYSVIEVISTLSFSVFVLLMSYITETFGITISFLLSAICLILEAILIYIRRDYLK
>NZ_CP046628.1|WP_157339397.1|1256862_1257627_+|alpha/beta-fold-hydrolase
MKVVEVGQENQDVIVLLHGGGLSWWQYQSQMELLCKNYHVVVPILDGHAGSNADFVSIEASAKQLLACIDKEYGGSVLLIAGLSLGGQILLEMLSLRKDICQYAIVESAAIIPDKLTAGLVAPLFSMSFPLIKKKWFAKMQFRYLGIRADLFEHYYEDTVKLSKQNLIAFTKASSLYQVKKNLKNSSARVRIIVGEKETRKMHASAKMLHAILPDSHLEIKSGLAHGQYSINHPDLYVKELLENFDSSTEQILK

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Crispr_ID: NZ_CP046628_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046628_2

1244559-1245919

TypeII

II-A,II-B

Consensus_repeat	Method
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	PILER-CR
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CRISPRCasFinder
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CRT

20 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP046628_2

>merge|NZ_CP046628|2|1244559-1245919|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACTGTGCAGCATTAGCTTTTGAGACAGCGCTGTGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACACTGCGTAGTTCGGATAAGCAGCCATCCATGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACGGTACATTCTTATATGGCGCTGAAACCTTTAGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACCCTTGTCTTGTAGGACCGATATGTCCTTACGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACCAGGGCCAAGGTCATGAATAACCTGCAAGTGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACCGACTTTAGCCGTTGCCATTGTCGGAATAAGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACAAATCGTCTTCGTTGATATCCATAGGGCTAGGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACAGCGAATGCTTGACGGTTATTTAAACCTGCGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACTTTGTCGGAAAAAATTGAAAAAATCGATAAAGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACAGAAAGGCAAAACCATGAAATTTAATGAATGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACAAACAGTAAATAAACGTCGAGCAATGTACGGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACAGCGTATTAGCGAGTTGGTTAAAACTGGTGGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACGCTGGGATGACGCAGGAAGAACTTGCGAATGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACCTTCCTAAGTTGTTATTCGATAGTTTGATTGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACGTTATCATCTCGATATGGGGTGTACCCTCTGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACTTGAAAATCTTTCTCTTTAATGCAATATCAGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACGAGGTATTTCAAGACAAGAACTGCTTACACGTTTCAGAGCTGTGTTGTTTCGAATGGTTCCAAAACAAAATACTCGTGCATTTCCTGATAAATATGAGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACGTTATCATCTCGATATGGGGTGTACCCTCTGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACTACTATTCTTAAGTTACTTCTACGGTTGTCGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC

>NZ_CP046628|2|2|1244559-1245919|PILER-CR
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TGTGCAGCATTAGCTTTTGAGACAGCGCTGT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	ACTGCGTAGTTCGGATAAGCAGCCATCCAT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GGTACATTCTTATATGGCGCTGAAACCTTTA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CCTTGTCTTGTAGGACCGATATGTCCTTAC
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CAGGGCCAAGGTCATGAATAACCTGCAAGT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CGACTTTAGCCGTTGCCATTGTCGGAATAA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AAATCGTCTTCGTTGATATCCATAGGGCTAG
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AGCGAATGCTTGACGGTTATTTAAACCTGC
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TTTGTCGGAAAAAATTGAAAAAATCGATAAA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AGAAAGGCAAAACCATGAAATTTAATGAAT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AAACAGTAAATAAACGTCGAGCAATGTACG
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AGCGTATTAGCGAGTTGGTTAAAACTGGTG
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GCTGGGATGACGCAGGAAGAACTTGCGAAT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CTTCCTAAGTTGTTATTCGATAGTTTGATT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GTTATCATCTCGATATGGGGTGTACCCTCT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TTGAAAATCTTTCTCTTTAATGCAATATCA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GAGGTATTTCAAGACAAGAACTGCTTACAC
GTTTCAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AAAATACTCGTGCATTTCCTGATAAATATGA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GTTATCATCTCGATATGGGGTGTACCCTCT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TACTATTCTTAAGTTACTTCTACGGTTGTC
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC

>NZ_CP046628|2|2|1244559-1245919|CRISPRCasFinder
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TGTGCAGCATTAGCTTTTGAGACAGCGCTGT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	ACTGCGTAGTTCGGATAAGCAGCCATCCAT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GGTACATTCTTATATGGCGCTGAAACCTTTA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CCTTGTCTTGTAGGACCGATATGTCCTTAC
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CAGGGCCAAGGTCATGAATAACCTGCAAGT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CGACTTTAGCCGTTGCCATTGTCGGAATAA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AAATCGTCTTCGTTGATATCCATAGGGCTAG
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AGCGAATGCTTGACGGTTATTTAAACCTGC
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TTTGTCGGAAAAAATTGAAAAAATCGATAAA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AGAAAGGCAAAACCATGAAATTTAATGAAT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AAACAGTAAATAAACGTCGAGCAATGTACG
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AGCGTATTAGCGAGTTGGTTAAAACTGGTG
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GCTGGGATGACGCAGGAAGAACTTGCGAAT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CTTCCTAAGTTGTTATTCGATAGTTTGATT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GTTATCATCTCGATATGGGGTGTACCCTCT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TTGAAAATCTTTCTCTTTAATGCAATATCA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GAGGTATTTCAAGACAAGAACTGCTTACAC
GTTTCAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AAAATACTCGTGCATTTCCTGATAAATATGA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GTTATCATCTCGATATGGGGTGTACCCTCT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TACTATTCTTAAGTTACTTCTACGGTTGTC
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC

>NZ_CP046628|2|2|1244559-1245919|CRT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TGTGCAGCATTAGCTTTTGAGACAGCGCTGT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	ACTGCGTAGTTCGGATAAGCAGCCATCCAT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GGTACATTCTTATATGGCGCTGAAACCTTTA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CCTTGTCTTGTAGGACCGATATGTCCTTAC
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CAGGGCCAAGGTCATGAATAACCTGCAAGT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CGACTTTAGCCGTTGCCATTGTCGGAATAA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AAATCGTCTTCGTTGATATCCATAGGGCTAG
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AGCGAATGCTTGACGGTTATTTAAACCTGC
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TTTGTCGGAAAAAATTGAAAAAATCGATAAA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AGAAAGGCAAAACCATGAAATTTAATGAAT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AAACAGTAAATAAACGTCGAGCAATGTACG
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AGCGTATTAGCGAGTTGGTTAAAACTGGTG
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GCTGGGATGACGCAGGAAGAACTTGCGAAT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CTTCCTAAGTTGTTATTCGATAGTTTGATT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GTTATCATCTCGATATGGGGTGTACCCTCT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TTGAAAATCTTTCTCTTTAATGCAATATCA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GAGGTATTTCAAGACAAGAACTGCTTACAC
GTTTCAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	AAAATACTCGTGCATTTCCTGATAAATATGA
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GTTATCATCTCGATATGGGGTGTACCCTCT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	TACTATTCTTAAGTTACTTCTACGGTTGTC
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046628.1\|WP_157339389.1\|1241635_1241980_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP046628.1\|WP_021142653.1\|1249423_1249900_+\|shikimate-kinase	unknown	unknown	gnl\|CDD\|234654
NZ_CP046628.1\|WP_157339388.1\|1240772_1241639_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP046628.1\|WP_157339387.1\|1236639_1240773_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_CP046628.1\|WP_039691771.1\|1249896_1250721_+\|prephenate-dehydratase	unknown	unknown	gnl\|CDD\|237013
NZ_CP046628.1\|WP_004232469.1\|1244052_1244469_+\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|179085
NZ_CP046628.1\|WP_157339386.1\|1235550_1236210_+\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
NZ_CP046628.1\|WP_157339395.1\|1252453_1253824_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|225174
NZ_CP046628.1\|WP_157339392.1\|1246178_1248014_+\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_CP046628.1\|WP_157339391.1\|1242927_1243308_+\|HicB-family-protein	unknown	unknown	gnl\|CDD\|374224
NZ_CP046628.1\|WP_157339396.1\|1255429_1256608_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP046628.1\|WP_157339390.1\|1242728_1242914_+\|addiction-module-toxin,-HicA-family	unknown	unknown	gnl\|CDD\|377942
NZ_CP046628.1\|WP_033153705.1\|1254280_1255372_+\|transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP046628.1\|WP_157339397.1\|1256862_1257627_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP046628.1\|WP_027968563.1\|1234787_1235561_+\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_CP046628.1\|WP_157339394.1\|1250871_1252341_+\|LytR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224235
NZ_CP046628.1\|WP_157339393.1\|1248147_1249431_+\|3-phosphoshikimate-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|235037
NZ_CP046628.1\|WP_157339702.1\|1241969_1242632_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_CP046628.1\|WP_157339398.1\|1257674_1258358_+\|response-regulator	unknown	unknown	gnl\|CDD\|223816
NZ_CP046628.1\|WP_134775434.1\|1236206_1236377_+\|NADH-quinone-oxidoreductase-subunit-L	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP046628.1\|WP_021142653.1\|1249423_1249900_+\|shikimate-kinase	gnl\|CDD\|234654	PRK00131, aroK, shikimate kinase; Reviewed.	1.13515e-61
NZ_CP046628.1\|WP_157339388.1\|1240772_1241639_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	9.32211e-129
NZ_CP046628.1\|WP_157339387.1\|1236639_1240773_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP046628.1\|WP_039691771.1\|1249896_1250721_+\|prephenate-dehydratase	gnl\|CDD\|237013	PRK11898, PRK11898, prephenate dehydratase; Provisional.	5.44614e-149
NZ_CP046628.1\|WP_157339389.1\|1241635_1241980_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	5.89226e-48
NZ_CP046628.1\|WP_157339386.1\|1235550_1236210_+\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	9.62471e-60
NZ_CP046628.1\|WP_157339395.1\|1252453_1253824_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	0
NZ_CP046628.1\|WP_157339392.1\|1246178_1248014_+\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_CP046628.1\|WP_157339391.1\|1242927_1243308_+\|HicB-family-protein	gnl\|CDD\|374224	pfam15919, HicB_lk_antitox, HicB_like antitoxin of bacterial toxin-antitoxin system. This is a family of HicB-like antitoxins.	1.21448e-15
NZ_CP046628.1\|WP_157339396.1\|1255429_1256608_+\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.32284e-39
NZ_CP046628.1\|WP_157339390.1\|1242728_1242914_+\|addiction-module-toxin,-HicA-family	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	5.25785e-13
NZ_CP046628.1\|WP_033153705.1\|1254280_1255372_+\|transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.39325e-06
NZ_CP046628.1\|WP_157339397.1\|1256862_1257627_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	3.04115e-12
NZ_CP046628.1\|WP_027968563.1\|1234787_1235561_+\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.66444e-129
NZ_CP046628.1\|WP_157339394.1\|1250871_1252341_+\|LytR-family-transcriptional-regulator	gnl\|CDD\|224235	COG1316, LytR, Transcriptional regulator [Transcription].	7.43333e-54
NZ_CP046628.1\|WP_157339393.1\|1248147_1249431_+\|3-phosphoshikimate-1-carboxyvinyltransferase	gnl\|CDD\|235037	PRK02427, PRK02427, 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional.	0
NZ_CP046628.1\|WP_157339702.1\|1241969_1242632_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	2.56242e-116
NZ_CP046628.1\|WP_157339398.1\|1257674_1258358_+\|response-regulator	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	6.26476e-65
NZ_CP046628.1\|WP_004232469.1\|1244052_1244469_+\|nucleoside-diphosphate-kinase	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	5.89419e-80

>NZ_CP046628.1|WP_004232469.1|1244052_1244469_+|nucleoside-diphosphate-kinase
MEKTFFMIKPDGVKRGLVGEVLKRIERRGFKIEKLEMRMATPELLEKHYEDLVDRPFFPLIVDFMTSGPVIAGVMSGEEVITSWRTMMGATNPKEALPGTIRGDFAQAPAEGAATFNIVHGSDSPESVEREIALWFGE
>NZ_CP046628.1|WP_157339391.1|1242927_1243308_+|HicB-family-protein
MLKTYPAIFHKEEGGSFWVEFPGFGGGTEGKDIEEAMKNAREMLDSSLAAYLDEGLALPKVIDMSELTVDDGFITLIQADPSPYLKKTKAIRKNVTVPEWLVRLADREQVNYSEVLTKALEKKLQL
>NZ_CP046628.1|WP_157339390.1|1242728_1242914_+|addiction-module-toxin,-HicA-family
MPKTVKELAKIAISKGWKEVRVKGSHHQFKKDGKAYIVTIPIHGNKVVGAGLERKNLKDLD
>NZ_CP046628.1|WP_157339702.1|1241969_1242632_+|type-II-A-CRISPR-associated-protein-Csn2
MKINFPILDEPLEISGGTILAVENVAVFSNLVRQLYSYTEESELKLFDKKLKSLKESELLLVTDILGFDVNSSSMLKLIHADLESQLNEKPEVKSMIENLADTITELIAYECLENELDLEYDEITVLELIKALGVKIETQSDTIFEKCFEILQIYNYLSKKKLLIFVNSGAYLTQNEMERLMEYIKLSNQKVLFLEPRKLYDFPQYVLDNDYFLIAENMS
>NZ_CP046628.1|WP_157339389.1|1241635_1241980_+|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTETVEERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNNSANKAMIDRLQANNPKKGSITLLTVTEKQFARMIYLNGERDTSVANSDKRLVFLGEDYSDED
>NZ_CP046628.1|WP_157339388.1|1240772_1241639_+|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTVIVNEHSKLSYKNNHLIFKDAYHTEMIHLEEIDILLLETTNIVLTTMLIERLVDKNILIIFCDEKRLPTAMLTPYYGRHDSSLQLTNQIAWDDDVKCDVWTNIIAQKILNQSMYLGECSFFEKSQSIMDLYHGLEPFDPSNREGHSARIYFNTLFGNDFSREQDNDINAGLDYGYTLLLSMFARELVVCGCMTQLGLKHSNQFNQFNLASDIMEPFRPIVDRIVYENRNASFVKIKRELFTMFDETYSYNNKEMYLNNIVSDYTKKVVKALNHNGKGVPEFRI
>NZ_CP046628.1|WP_157339387.1|1236639_1240773_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKKSYSIGLDIGTNSVGWSVITDDYKVPAKKLKVLGNTDKKYIKKNLLGALLFDSGETAEATRLKRTARRRYTRRKNRLRYLQEIFGKEMAKVDESFFQRLEESFLTDDDKTFDSHPIFGNKVEEDAYHQEFPTIYHLRKHLADSPEKADLRLVYLALAHMIKFRGHFLIEGQLDAENTDVQKLFNDFVETYDKIADESHLSEVEVDASSILTNKISKSRRLENLIKQYPTEKKNTLFGNLVALALGLQPNFKTNFKLSEDAKLQFSKDTYDEDLEELLGKIGDDYADLFTAAKNLYDAILLSGILTVDDNSTKAPLSASMIKRYEEHHEDLEKLKTFIKVNNSDKYHEIFKDKSKNGYAGYIENGVKQDIFYKHLKSIISEKNGGQYFLDKIEREDFLRKQRTFDNGSIPHQIHLQEMRAILRRQGEYYPFLKENQAKIEKILTFRIPYYVGPLARKNSRFAWAKYHSDEPITPWNLDEVVDKEKSAEKFITRMTLNDLYLPEEKVLPKHSHVYETFAVYNELTKIKYVNEQGKSFFFDANMKQEIFDYVFKENRKVTKAKLLSYLNNEFEEFRINDLIGLDKDSKSFNASLGTYHDLKKILDKSFLDDKTNEQIIEDIVLTLTLFEDRDMIHERLQKYSEIFTSQQLKKLERRHYTGWGRLSYKLINGIRNKENNKTILDFLIDDGHANRNFMQLINDDSLSFKTIIQEAQVIGDVDDIEAVVHDLPGSPAIKKGILQSVKIVDELVKVMGHNPQNIVIEMARENQITGYGRNKSNQRLKRLQDSLKEFGSDILSKKKPSYIDSKVENSHLQNDRLFLYYIQNGKDMYTGEELDIDHLSDYDIDHIIPQAFIKDNSIDNRVLTSSAKNRGKSDDVPSIEIVRNRKSYWYKLYKSGLISKRKFDNLTKAERGGLTEADKAGFIKRQLVETRQITKHVAQILDARFNTKRDENDKVIRDVKVITLKSSLVSQFRKEFKFYKVREINDYHHAHDAYLNAVVGTALLKKYPKLAPEFVYGEYKKYDVRKLVAKSSDNHSELGKATAKYFFYSNLMNFFKTEVKYADGRVFERPDIETNADGEVVWNKRRDFDIVRKVLSYPQVNIVKKVEVQTGGFSKESILPKGDSDKLIPRKTKKFQWETQKYGGFDSPTVAYSVLVVADVEKGKTRKLKTVKELVGISIMERSSFEENPVSFLEKKEYHNVQEDKLIKLPKYSLFEFEGGRRRLLASAIELQKGNEVVLPQYMVNLLYHSQHVNNSHKPEHLNYVKQHKDEFKDIFNLIISIARINILKPKVVDNLINEFTEYGQEDISSLSESFINLLKFTSFGAPGAFKFLKLDVKQSNLRYQTVTEILNATLIHQSVTGLYETRIDLSKLGEE
>NZ_CP046628.1|WP_134775434.1|1236206_1236377_+|NADH-quinone-oxidoreductase-subunit-L
MTFAWYFWLLFAVAWIFAITFWVKSSNISQKWLRITYVICGIIAFLLPFFWGWLVS
>NZ_CP046628.1|WP_157339386.1|1235550_1236210_+|TIGR01906-family-membrane-protein
MKTKIWTFSTWLWLLSLAVLVAIYGAWLIYPLEIDWLKLSLQVTITKDELLKNFNILMTYLTNPLSHKLAMPDFSSSASGLKHFRDVKHLFHLAQAVFVILLYPSWRFLKNSRAKKSLFLHQRTFTFAAFLPIVIAVAGLLIGFDQFFTLFHEALFPGDSSWLFNPATDPIIWVLPEEYFMHCFIIFFVAYEVMMLSLVATARKQLNHRLKNNERKDEK
>NZ_CP046628.1|WP_027968563.1|1234787_1235561_+|TIGR01457-family-HAD-type-hydrolase
MTYKGYLIDLDGTIYKGKDRIPAGERFIQRLQERNIPYVLVTNNSTRTPEKVQEMLSTQFNVHTPLETIYTATMATIDYMNDLNRGKTVYVIGETGLKTAIAEAGYVEDTENPAYVVVGLDNDLTYEKLAVATLAIQKGAVFIGTNPDLNIPTERGLMPGAGAINKLLEAATRVQPVFIGKPNAIIMNKALDVLGVKREEAIMVGDNYLTDIMAGIQNDIATLLVTTGFTKPEEVPTLPVKPNHVLASLDEWNFDEN
>NZ_CP046628.1|WP_157339392.1|1246178_1248014_+|elongation-factor-4
MDIQELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFSYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVIGLDASEAVLASAKAGIGIEEILEQIVEYVPAPAGDVEAPLQALIFDSVYDAYRGVILQVRIVNGMVKPGDTIQLMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYIAASIKTVADTRVGDTVTLAENPAEAPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGDMLEVSNPSEFPDPTKVASIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDENRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYEISEYRKSKLVKMDILLNGDKVDALSFIVHNEFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDESSKK
>NZ_CP046628.1|WP_157339393.1|1248147_1249431_+|3-phosphoshikimate-1-carboxyvinyltransferase
MKLLTNVSQLQGTLRVPGDKSISHRSIMFGSLAKGKTTVRDILRGEDVLSTMQVFRDLGVDIQDDGELVTITGVGFDGLKAPKNKLNMGNSGTSIRLISGVLAGQDFTVEMFGDDSLSKRPMDRVTIPLRQMGVEVSGQTERDLPPLTMHGSKALKPIHYQLPVASAQVKSALIFAALQADGESVIIEKEKTRNHTEDMIVQFGGKIDVNGKEIRIKGGQEFTGQDVVVPGDISSAAFWLVAGLIVPNAKVTLKNVGINETRTGILDVIKAMGGKMTISDVDDIAKSATIIVETSELHGTEIGGEIIPRLIDELPIIALLATQANGTTVIRDAEELKVKETDRIQVVADALNAMGADITPTDDGMIIKGKTPLHGAKINTFGDHRIGMMTAIAALLVSHGDVELERAEAINTSYPSFFNDLEVLSRG
>NZ_CP046628.1|WP_021142653.1|1249423_1249900_+|shikimate-kinase
MARIIIGFMGSGKSTISSLLDKDYVDMDALITERIGMSIADFFEKEGEAKFREIESQVLAELVNSEHVISTGGGVVINPINRDILAKNGETIYLKADFDTLYDRIKNDTKNVRPLFINNSKEAFKAIFDGRREMYESAANRIIEVAGKTPEEIVEEIG
>NZ_CP046628.1|WP_039691771.1|1249896_1250721_+|prephenate-dehydratase
MKVGYLGPSGSFTHNVAVKAFPDDERMPFANITEVIKSYEEGVVDYAIIPVENSIEGSVHETLDYLYHQANIEAVAEMIQPIKQQLLATSQDKKIEKIFSHPQAIAQGKKYIKAHYPNAQIEMTASTAYAARYIAENPDEPYAAIAPAAAAKEYGLVIIAKDIQEMDENYTRFWLLGRQKPVFDLPKSQQKLSLAITLQDNLPGALYKALSVFAWRGINLTKIESRPLKTALGEYFFIVDVDNSNEALVACALEELQLLGIDYKTLGNYDVYKL
>NZ_CP046628.1|WP_157339394.1|1250871_1252341_+|LytR-family-transcriptional-regulator
MANNRLSRHEELRYQYLLGNLEYLNAQQKEEFDYLYQKKLMSMQQPSNYSSSAYNETCDDQYDDYGYYDDYNNDYYDDYEDSAAYVDYDDYSGYDSYDDQVTSQGLPKYPKFEKVSRPKRKHQKKPKKSSYLDYYEGIDDKPVKKVKKSKKKKRKKRLKHFLQFFAMLIVLVMAGMIYMFFHGVKEVSSGETNYSAAVTEPFNGQDSKDGTNILILGSDKRISQGSSDARTDTIMVLNIGNKEGKVKLVSFMRDTLVNINGVSYNDYANDQKLNVAFNIGEQDESQGAELMRKTLKDNFDINIKYYVMVDFETFAEAINTLFPNGVDIDAKFGTVDGQEVSSVEVPDDLNMQPDGTVPNQTIEVGEQKMDGRTLLNYARFRKDDDGDYGRTQRQQQVISAIVSQIKDPSKLFTGSAAIGKIYALTSTNVSYPFLVKEGLGVVTSGKKGIEQKTIPEEGDWTDDYDMYGGLGISIDFNKYQEELKELGLR
>NZ_CP046628.1|WP_157339395.1|1252453_1253824_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MLEKNSIVEVEITDLSHEGAGVAKVDGFVFFVENALPGEKIKMRVLKVKKNIGFGKVEEYLTISEHRNQDLNVDYLRTGIADFGHLAYSEQLKFKRKQVADNLYKTAGISDVEVAETLGMEHPYAYRNKAQVPVRRVNGQLETGFFRKHSHDLMPISDFYIQNKEIDRLINFTRDLLRRFDLKPYDEKEQTGLIRNLVVRRGHYSGEMMLVFVTTRPKIFRIEQIIEKIVAEFPAVKSIVQNINDKNTNAIFGNDFRTLYGKDTIVDSMLGNQYEISARSFYQVNTEMAEKLYQTAIDFSDLTADDIVIDAYSGIGTIGLSFAKNVKAVYGVEVIEEAVEDAKRNAALNGITNAHYVADSAEHAMATWSKNGIKPSVILVDPPRKGLTENFIKASVAMQPEKVTYISCNPATMARDIKIYQELGYKLQKVQPVDLFPNTHHVEAVSLLVRATETAK
>NZ_CP046628.1|WP_033153705.1|1254280_1255372_+|transporter
MSKRIFNLYVMNIFLSGLPYYFVTMLLLKHLGFSFTEIASLSVITELCGSVFDIPLSVISSKFGYKKILVISNFLLILALSCLLFGKSNIIYISAISFGLSESLSSGVLNAYNFEIIDDEVVYKSFLKYLNTIKYVFIAIVTIISPYLLNRNFSYPIIISIVFVVLSQLSLIGLPEIRNTLNNDQKIFSIDNVKDIPWNLILLGVAFSTLIMISNSYAGIFLNEQGLSLDMLGIVLFMFNISMALGSYLKIKFKISLMLPILAIFMFFQTNLFIQIITFLLMRILNSSYNNHFYSKFNMSIEKNRAVSWSVYNLFISISFMVADFLGGIFADNFSIRSNYLIFGTVSLFCLVFFSFSNREKRT
>NZ_CP046628.1|WP_157339396.1|1255429_1256608_+|MFS-transporter
MSNSFIKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVPILIGISSFVASILVPLVTKRLALNKVLSLSQFGKTILLLILVGMFIVMKSVPPLVMYLFVVVISILDGFAAPVSYAIVPRYATDLGKANSALSMSGEATQLVGWGLGGLLFATIGLLSTTLIILLLYIISSFMMLFLPDAEVEVLESETNLDILVKGWKSVARDPRLRLFISANLFEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIITSGLIAFRLSEKFLAAKWKSILFPLVSIAIVTLAIILFPNAQMFLFFSALVGMLSQLKEVPESVFLQETVEENNLVNVYSVIEVISTLSFSVFVLLMSYITETFGITISFLLSAICLILEAILIYIRRDYLK
>NZ_CP046628.1|WP_157339397.1|1256862_1257627_+|alpha/beta-fold-hydrolase
MKVVEVGQENQDVIVLLHGGGLSWWQYQSQMELLCKNYHVVVPILDGHAGSNADFVSIEASAKQLLACIDKEYGGSVLLIAGLSLGGQILLEMLSLRKDICQYAIVESAAIIPDKLTAGLVAPLFSMSFPLIKKKWFAKMQFRYLGIRADLFEHYYEDTVKLSKQNLIAFTKASSLYQVKKNLKNSSARVRIIVGEKETRKMHASAKMLHAILPDSHLEIKSGLAHGQYSINHPDLYVKELLENFDSSTEQILK
>NZ_CP046628.1|WP_157339398.1|1257674_1258358_+|response-regulator
MYKILVVDDDFEILKLMRTILEMKNYDVTTYQGITLPLNSKDFQGFDLILLDVMMPDIDGLQVCRQIRDKMSAPIIFVSAKDEEDDIVTGLNLGGDDYITKPFSVKQLVAKVAAHLKREERFRQAESDEKIIRELLPITFYLQEKTVCVNGNIVPLTSREYDLLDLLSANRNKVFTREDIYSHIYDDEADALFRSISEYVYQIRVKFSVYDINPIKTVRGIGYKWYD

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP046628_2	2.6\|1244927\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244927-1244956	30	MK448712	Streptococcus phage Javan237, complete genome	14411-14440	0	1.0
NZ_CP046628_2	2.6\|1244927\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244927-1244956	30	MK448880	Streptococcus phage Javan238, complete genome	14411-14440	0	1.0
NZ_CP046628_2	2.7\|1244993\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244993-1245023	31	MK448875	Streptococcus phage Javan210, complete genome	9164-9194	0	1.0
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	KY705259	Streptococcus phage P5641, complete genome	21448-21478	0	1.0
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	CP029253	Streptococcus phage VS-2018a, complete genome	36967-36997	0	1.0
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	MH937467	Streptococcus phage CHPC877, complete genome	21682-21712	0	1.0
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	MH937465	Streptococcus phage CHPC873, complete genome	22225-22255	0	1.0
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	FJ965538	Streptococcus phage 5093, complete genome	28645-28675	0	1.0
NZ_CP046628_2	2.2\|1244662\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244662-1244691	30	MK448706	Streptococcus phage Javan221, complete genome	34475-34504	1	0.967
NZ_CP046628_2	2.4\|1244795\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244795-1244824	30	MK448703	Streptococcus phage Javan207, complete genome	41538-41567	1	0.967
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	KY705255	Streptococcus phage P0095, complete genome	18988-19018	1	0.968
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	MH892373	Streptococcus phage SW27, complete genome	19101-19131	1	0.968
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	KX879643	Streptococcus phage CHPC1151, complete genome	19632-19662	1	0.968
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	MK202161	Streptococcus phage CHPC1282, complete genome	18965-18995	1	0.968
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	KY705252	Streptococcus phage P0092, complete genome	19150-19180	1	0.968
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	KY705253	Streptococcus phage P0093, complete genome	19150-19180	1	0.968
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	MH892367	Streptococcus phage SW19, complete genome	19713-19743	1	0.968
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	MH892355	Streptococcus phage SW4, complete genome	19005-19035	1	0.968
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	KY705254	Streptococcus phage P0094, complete genome	19150-19180	1	0.968
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	MK202159	Streptococcus phage CHPC1198, complete genome	19049-19079	1	0.968
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	MK202160	Streptococcus phage CHPC1232, complete genome	19023-19053	1	0.968
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	MH973663	Streptococcus phage SW24, complete genome	19224-19254	1	0.968
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	MH937471	Streptococcus phage CHPC927, complete genome	22564-22594	1	0.968
NZ_CP046628_2	2.17\|1245655\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245655-1245684	30	MK448706	Streptococcus phage Javan221, complete genome	7630-7659	1	0.967
NZ_CP046628_2	2.17\|1245655\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245655-1245684	30	MK448878	Streptococcus phage Javan224, complete genome	8835-8864	1	0.967
NZ_CP046628_1	1.1\|1243487\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1243487-1243516	30	MK448873	Streptococcus phage Javan202, complete genome	5741-5770	2	0.933
NZ_CP046628_2	2.4\|1244795\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244795-1244824	30	MK448899	Streptococcus phage Javan288, complete genome	36029-36058	2	0.933
NZ_CP046628_2	2.4\|1244795\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244795-1244824	30	MH937498	Streptococcus phage CHPC1057, complete genome	23946-23975	2	0.933
NZ_CP046628_2	2.4\|1244795\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244795-1244824	30	NC_007019	Streptococcus phage 2972, complete genome	24268-24297	2	0.933
NZ_CP046628_2	2.4\|1244795\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244795-1244824	30	AY699705	Streptococcus thermophilus bacteriophage 2972, complete genome	24268-24297	2	0.933
NZ_CP046628_2	2.4\|1244795\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244795-1244824	30	MK448705	Streptococcus phage Javan215, complete genome	37954-37983	2	0.933
NZ_CP046628_2	2.4\|1244795\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244795-1244824	30	MH937484	Streptococcus phage CHPC1008, complete genome	23926-23955	2	0.933
NZ_CP046628_2	2.4\|1244795\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244795-1244824	30	MK448875	Streptococcus phage Javan210, complete genome	36429-36458	2	0.933
NZ_CP046628_2	2.8\|1245060\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245060-1245089	30	MK448899	Streptococcus phage Javan288, complete genome	26908-26937	2	0.933
NZ_CP046628_2	2.5\|1244861\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244861-1244890	30	MK448705	Streptococcus phage Javan215, complete genome	9309-9338	3	0.9
NZ_CP046628_2	2.4\|1244795\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244795-1244824	30	MK448873	Streptococcus phage Javan202, complete genome	38140-38169	4	0.867
NZ_CP046628_1	1.1\|1243487\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1243487-1243516	30	NZ_CP031600	Roseovarius indicus strain DSM 26383 plasmid pRIdsm_02, complete sequence	80931-80960	5	0.833
NZ_CP046628_2	2.5\|1244861\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244861-1244890	30	MK448721	Streptococcus phage Javan263, complete genome	12537-12566	5	0.833
NZ_CP046628_2	2.5\|1244861\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244861-1244890	30	MK448890	Streptococcus phage Javan264, complete genome	10588-10617	5	0.833
NZ_CP046628_2	2.16\|1245589\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245589-1245618	30	NZ_CP015592	Bacillus cereus strain AR156 plasmid pAR460, complete sequence	91392-91421	5	0.833
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	AP023037	Helicobacter suis NHP19-0020 plasmid pNHP190020_1 DNA, complete genome	38374-38404	6	0.806
NZ_CP046628_2	2.10\|1245193\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245193-1245222	30	MK448874	Streptococcus phage Javan206, complete genome	7418-7447	6	0.8
NZ_CP046628_2	2.10\|1245193\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245193-1245222	30	MK448875	Streptococcus phage Javan210, complete genome	7786-7815	6	0.8
NZ_CP046628_2	2.16\|1245589\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245589-1245618	30	NZ_KX258624	Bacillus thuringiensis strain INTA Fr7-4 plasmid pFR260, complete sequence	49636-49665	6	0.8
NZ_CP046628_1	1.7\|1243885\|31\|NZ_CP046628\|CRISPRCasFinder,CRT	1243885-1243915	31	NZ_CP016179	Vibrio breoganii strain FF50 plasmid unnamed1, complete sequence	141377-141407	7	0.774
NZ_CP046628_2	2.1\|1244595\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244595-1244625	31	AP013397	Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-U-MedDCM-OCT-S25-C46	24999-25029	7	0.774
NZ_CP046628_2	2.1\|1244595\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244595-1244625	31	NZ_CP013691	Myroides odoratimimus strain PR63039 plasmid p63039, complete sequence	12502-12532	7	0.774
NZ_CP046628_2	2.1\|1244595\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244595-1244625	31	NZ_CP013691	Myroides odoratimimus strain PR63039 plasmid p63039, complete sequence	84365-84395	7	0.774
NZ_CP046628_2	2.2\|1244662\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244662-1244691	30	MK448707	Streptococcus phage Javan227, complete genome	39552-39581	7	0.767
NZ_CP046628_2	2.2\|1244662\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244662-1244691	30	MK448879	Streptococcus phage Javan226, complete genome	34463-34492	7	0.767
NZ_CP046628_2	2.5\|1244861\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244861-1244890	30	MK448932	Streptococcus phage Javan42, complete genome	8032-8061	7	0.767
NZ_CP046628_2	2.5\|1244861\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244861-1244890	30	MK448669	Streptococcus phage Javan11, complete genome	8032-8061	7	0.767
NZ_CP046628_2	2.5\|1244861\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244861-1244890	30	MN694727	Marine virus AFVG_250M275, complete genome	27697-27726	7	0.767
NZ_CP046628_2	2.8\|1245060\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245060-1245089	30	NC_049510	Erwinia phage phiEaP-8, complete genome	45803-45832	7	0.767
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	NZ_CP040803	Streptococcus salivarius strain LAB813 plasmid pSAL813, complete sequence	64178-64208	7	0.774
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	MK448711	Streptococcus phage Javan235, complete genome	4855-4885	7	0.774
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	MN694457	Marine virus AFVG_250M832, complete genome	2948-2978	7	0.774
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	MN693808	Marine virus AFVG_250M831, complete genome	2946-2976	7	0.774
NZ_CP046628_2	2.10\|1245193\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245193-1245222	30	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	409143-409172	7	0.767
NZ_CP046628_2	2.10\|1245193\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245193-1245222	30	MK765588	Tortoise microvirus 38 isolate 38_SP_76, complete genome	1730-1759	7	0.767
NZ_CP046628_2	2.12\|1245325\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245325-1245354	30	GU071094	Synechococcus phage S-SM1, complete genome	112992-113021	7	0.767
NZ_CP046628_2	2.13\|1245391\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245391-1245420	30	HG818824	Citrobacter phage CR8 complete genome	17437-17466	7	0.767
NZ_CP046628_2	2.14\|1245457\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245457-1245486	30	KC954775	UNVERIFIED: Cronobacter phage S13, complete genome	106183-106212	7	0.767
NZ_CP046628_2	2.14\|1245457\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245457-1245486	30	NC_028773	Cronobacter phage S13, complete genome	106183-106212	7	0.767
NZ_CP046628_2	2.16\|1245589\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245589-1245618	30	NZ_CP014284	Bacillus thuringiensis strain Bt185 plasmid pBT1850294, complete sequence	150729-150758	7	0.767
NZ_CP046628_2	2.16\|1245589\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245589-1245618	30	NZ_CP011350	Bacillus thuringiensis strain YC-10 plasmid pYC1, complete sequence	703942-703971	7	0.767
NZ_CP046628_2	2.16\|1245589\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245589-1245618	30	NZ_CP013056	Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-1, complete sequence	23480-23509	7	0.767
NZ_CP046628_2	2.16\|1245589\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245589-1245618	30	NZ_CP032609	Bacillus thuringiensis strain QZL38 plasmid p.2, complete sequence	242630-242659	7	0.767
NZ_CP046628_2	2.16\|1245589\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245589-1245618	30	NZ_AP014866	Bacillus thuringiensis serovar tolworthi strain Pasteur Institute Standard strain plasmid pKK2, complete sequence	5835-5864	7	0.767
NZ_CP046628_2	2.16\|1245589\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245589-1245618	30	NZ_CP004876	Bacillus thuringiensis serovar kurstaki str. HD-1 plasmid pBMB299, complete sequence	144457-144486	7	0.767
NZ_CP046628_2	2.16\|1245589\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245589-1245618	30	NC_017203	Bacillus thuringiensis serovar chinensis CT-43 plasmid pCT281, complete sequence	176623-176652	7	0.767
NZ_CP046628_2	2.16\|1245589\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245589-1245618	30	NC_020384	Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-285, complete sequence	180848-180877	7	0.767
NZ_CP046628_2	2.16\|1245589\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245589-1245618	30	NZ_CP015152	Bacillus thuringiensis strain Bc601 plasmid pBTBC2, complete sequence	7921-7950	7	0.767
NZ_CP046628_2	2.16\|1245589\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245589-1245618	30	NZ_CP004861	Bacillus thuringiensis serovar kurstaki str. YBT-1520 plasmid pBMB293, complete sequence	141788-141817	7	0.767
NZ_CP046628_2	2.16\|1245589\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245589-1245618	30	NZ_CP010111	Bacillus thuringiensis serovar indiana strain HD521 plasmid pBTHD521-5, complete sequence	47351-47380	7	0.767
NZ_CP046628_2	2.16\|1245589\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245589-1245618	30	NZ_CP010091	Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB267, complete sequence	136520-136549	7	0.767
NZ_CP046628_1	1.1\|1243487\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1243487-1243516	30	MH363700	Vibrio phage VP-1, complete genome	28408-28437	8	0.733
NZ_CP046628_1	1.1\|1243487\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1243487-1243516	30	NC_048765	Vibrio phage VAP7, complete genome	52761-52790	8	0.733
NZ_CP046628_1	1.4\|1243685\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1243685-1243714	30	NZ_CP054718	Salmonella enterica strain 85-0120 plasmid unnamed2, complete sequence	24867-24896	8	0.733
NZ_CP046628_1	1.4\|1243685\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1243685-1243714	30	NZ_CP054718	Salmonella enterica strain 85-0120 plasmid unnamed2, complete sequence	24221-24250	8	0.733
NZ_CP046628_1	1.4\|1243685\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1243685-1243714	30	NC_049466	Escherichia phage vB_EcoM_4HA13, complete genome	48275-48304	8	0.733
NZ_CP046628_1	1.5\|1243751\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1243751-1243781	31	NZ_AP019532	Serratia symbiotica strain IS plasmid pSsyis1, complete sequence	46299-46329	8	0.742
NZ_CP046628_1	1.6\|1243818\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1243818-1243848	31	NZ_AP019532	Serratia symbiotica strain IS plasmid pSsyis1, complete sequence	46299-46329	8	0.742
NZ_CP046628_1	1.7\|1243885\|31\|NZ_CP046628\|CRISPRCasFinder,CRT	1243885-1243915	31	KF147891	Pseudomonas phage PaBG, complete genome	213439-213469	8	0.742
NZ_CP046628_2	2.7\|1244993\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244993-1245023	31	MN648195	Acinetobacter phage Konradin, complete genome	67977-68007	8	0.742
NZ_CP046628_2	2.7\|1244993\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244993-1245023	31	MT385367	Acinetobacter phage Abraxas, complete genome	69866-69896	8	0.742
NZ_CP046628_2	2.7\|1244993\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244993-1245023	31	MN662249	Acinetobacter phage Stupor, complete genome	67969-67999	8	0.742
NZ_CP046628_2	2.7\|1244993\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244993-1245023	31	NC_049493	Acinetobacter phage vB_AbaP_Lazarus, complete genome	68840-68870	8	0.742
NZ_CP046628_2	2.7\|1244993\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244993-1245023	31	MN782535	Acinetobacter phage Lazarus, complete genome	68840-68870	8	0.742
NZ_CP046628_2	2.7\|1244993\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244993-1245023	31	NC_049479	Acinetobacter phage vB_AbaP_Konradin, complete genome	67977-68007	8	0.742
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	NZ_CP024404	Borrelia miyamotoi strain Izh-4 plasmid pIzh4-lp13, complete sequence	1816-1846	8	0.742
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	NZ_CP024220	Borrelia miyamotoi strain Izh-5 plasmid pIzh5-12	11411-11441	8	0.742
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	NZ_CP024343	Borrelia miyamotoi strain Yekat-1 plasmid pYkt1-8	11410-11440	8	0.742
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	NZ_CP024365	Borrelia miyamotoi strain Izh-16 plasmid pIzh16-10	1833-1863	8	0.742
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	NZ_CP024386	Borrelia miyamotoi strain Izh-14 plasmid pIzh14-11	11450-11480	8	0.742
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	NC_014628	Paenibacillus polymyxa SC2 plasmid pSC2, complete sequence	426989-427019	8	0.742
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	MT430910	Streptococcus phage smHBZ8, complete genome	9288-9318	8	0.742
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	MN938931	Streptococcus phage D4446, complete genome	25206-25236	8	0.742
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	AP014365	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S41-C61, * SEQUENCING IN PROGRESS *	10421-10451	8	0.742
NZ_CP046628_2	2.13\|1245391\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245391-1245420	30	NZ_CP021525	Acetobacter ascendens strain SRCM101447 plasmid pAP1447-1	72958-72987	8	0.733
NZ_CP046628_2	2.13\|1245391\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245391-1245420	30	NZ_CP024882	Citrobacter freundii strain AR_0022 plasmid unitig_1_pilon, complete sequence	3582-3611	8	0.733
NZ_CP046628_2	2.13\|1245391\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245391-1245420	30	NZ_CP032180	Citrobacter freundii strain AR_0116 plasmid unnamed2, complete sequence	133340-133369	8	0.733
NZ_CP046628_2	2.13\|1245391\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245391-1245420	30	NZ_CP037863	Citrobacter sp. LY-1 plasmid unnamed2, complete sequence	102740-102769	8	0.733
NZ_CP046628_2	2.16\|1245589\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245589-1245618	30	NZ_CP020081	Vibrio campbellii strain 20130629003S01 plasmid pVCGX4, complete sequence	64797-64826	8	0.733
NZ_CP046628_2	2.16\|1245589\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245589-1245618	30	NZ_CP019297	Vibrio campbellii strain LMB29 plasmid pLMB99, complete sequence	6405-6434	8	0.733
NZ_CP046628_2	2.16\|1245589\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245589-1245618	30	NZ_CP019297	Vibrio campbellii strain LMB29 plasmid pLMB99, complete sequence	92347-92376	8	0.733
NZ_CP046628_2	2.17\|1245655\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245655-1245684	30	MN694111	Marine virus AFVG_250M218, complete genome	3255-3284	8	0.733
NZ_CP046628_1	1.3\|1243619\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1243619-1243648	30	NZ_CP023002	Bacillus anthracis strain 14RA5914 plasmid pX01, complete sequence	231-260	9	0.7
NZ_CP046628_2	2.6\|1244927\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244927-1244956	30	AP014011	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C79-MedDCM-OCT-S38-C32, * SEQUENCING IN PROGRESS *	8297-8326	9	0.7
NZ_CP046628_2	2.6\|1244927\|30\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1244927-1244956	30	AP013546	Uncultured phage_MedDCM-OCT-S37-C6 DNA, complete genome, group G9, isolate: uvMED-CGR-C79-MedDCM-OCT-S37-C6	17920-17949	9	0.7
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	MK448901	Streptococcus phage Javan306, complete genome	31434-31464	9	0.71
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	NZ_CP014152	Clostridium botulinum strain BrDura plasmid pRSJ20_1, complete sequence	40096-40126	9	0.71
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	NZ_CP024773	Bacillus thuringiensis LM1212 plasmid pLM2, complete sequence	66275-66305	9	0.71
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	NZ_CP013710	Clostridium botulinum strain F634 plasmid pRSJ2_3, complete sequence	239259-239289	9	0.71
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	NC_010418	Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence	168726-168756	9	0.71
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	NZ_CP042422	Leuconostoc lactis strain CBA3622 plasmid unnamed2, complete sequence	22821-22851	9	0.71
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	NZ_CP042423	Leuconostoc lactis strain CBA3622 plasmid unnamed3	112-142	9	0.71
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	NZ_CP042423	Leuconostoc lactis strain CBA3622 plasmid unnamed3	45166-45196	9	0.71
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	NZ_CP042423	Leuconostoc lactis strain CBA3622 plasmid unnamed3	51225-51255	9	0.71
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	NZ_CP041075	Bacillus tropicus strain LM1212-W3 plasmid p2, complete sequence	105068-105098	9	0.71
NZ_CP046628_2	2.9\|1245126\|31\|NZ_CP046628\|PILER-CR,CRISPRCasFinder,CRT	1245126-1245156	31	JN638751	Bacillus phage G, complete genome	466718-466748	9	0.71

1. spacer 2.6|1244927|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448712 (Streptococcus phage Javan237, complete genome) position: , mismatch: 0, identity: 1.0

cgactttagccgttgccattgtcggaataa	CRISPR spacer
cgactttagccgttgccattgtcggaataa	Protospacer
******************************

2. spacer 2.6|1244927|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448880 (Streptococcus phage Javan238, complete genome) position: , mismatch: 0, identity: 1.0

cgactttagccgttgccattgtcggaataa	CRISPR spacer
cgactttagccgttgccattgtcggaataa	Protospacer
******************************

3. spacer 2.7|1244993|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448875 (Streptococcus phage Javan210, complete genome) position: , mismatch: 0, identity: 1.0

aaatcgtcttcgttgatatccatagggctag	CRISPR spacer
aaatcgtcttcgttgatatccatagggctag	Protospacer
*******************************

4. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to KY705259 (Streptococcus phage P5641, complete genome) position: , mismatch: 0, identity: 1.0

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
tttgtcggaaaaaattgaaaaaatcgataaa	Protospacer
*******************************

5. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to CP029253 (Streptococcus phage VS-2018a, complete genome) position: , mismatch: 0, identity: 1.0

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
tttgtcggaaaaaattgaaaaaatcgataaa	Protospacer
*******************************

6. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MH937467 (Streptococcus phage CHPC877, complete genome) position: , mismatch: 0, identity: 1.0

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
tttgtcggaaaaaattgaaaaaatcgataaa	Protospacer
*******************************

7. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MH937465 (Streptococcus phage CHPC873, complete genome) position: , mismatch: 0, identity: 1.0

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
tttgtcggaaaaaattgaaaaaatcgataaa	Protospacer
*******************************

8. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to FJ965538 (Streptococcus phage 5093, complete genome) position: , mismatch: 0, identity: 1.0

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
tttgtcggaaaaaattgaaaaaatcgataaa	Protospacer
*******************************

9. spacer 2.2|1244662|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448706 (Streptococcus phage Javan221, complete genome) position: , mismatch: 1, identity: 0.967

actgcgtagttcggataagcagccatccat	CRISPR spacer
actgcgtagtttggataagcagccatccat	Protospacer
***********.******************

10. spacer 2.4|1244795|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448703 (Streptococcus phage Javan207, complete genome) position: , mismatch: 1, identity: 0.967

ccttgtcttgtaggaccgatatgtccttac	CRISPR spacer
ccttgtcttgtaggactgatatgtccttac	Protospacer
****************.*************

11. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to KY705255 (Streptococcus phage P0095, complete genome) position: , mismatch: 1, identity: 0.968

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
tttgtcggaaaaaattgaaaaaatcgataac	Protospacer
******************************

12. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MH892373 (Streptococcus phage SW27, complete genome) position: , mismatch: 1, identity: 0.968

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
tttgtcggaaaaaattgaaaaaatcgataac	Protospacer
******************************

13. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to KX879643 (Streptococcus phage CHPC1151, complete genome) position: , mismatch: 1, identity: 0.968

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
tttgtcggaaaaaattgaaaaaatcgataac	Protospacer
******************************

14. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK202161 (Streptococcus phage CHPC1282, complete genome) position: , mismatch: 1, identity: 0.968

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
tttgtcggaaaaaattgaaaaaatcgataac	Protospacer
******************************

15. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to KY705252 (Streptococcus phage P0092, complete genome) position: , mismatch: 1, identity: 0.968

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
tttgtcggaaaaaattgaaaaaatcgataac	Protospacer
******************************

16. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to KY705253 (Streptococcus phage P0093, complete genome) position: , mismatch: 1, identity: 0.968

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
tttgtcggaaaaaattgaaaaaatcgataac	Protospacer
******************************

17. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MH892367 (Streptococcus phage SW19, complete genome) position: , mismatch: 1, identity: 0.968

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
tttgtcggaaaaaattgaaaaaatcgataac	Protospacer
******************************

18. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MH892355 (Streptococcus phage SW4, complete genome) position: , mismatch: 1, identity: 0.968

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
tttgtcggaaaaaattgaaaaaatcgataac	Protospacer
******************************

19. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to KY705254 (Streptococcus phage P0094, complete genome) position: , mismatch: 1, identity: 0.968

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
tttgtcggaaaaaattgaaaaaatcgataac	Protospacer
******************************

20. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK202159 (Streptococcus phage CHPC1198, complete genome) position: , mismatch: 1, identity: 0.968

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
tttgtcggaaaaaattgaaaaaatcgataac	Protospacer
******************************

21. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK202160 (Streptococcus phage CHPC1232, complete genome) position: , mismatch: 1, identity: 0.968

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
tttgtcggaaaaaattgaaaaaatcgataac	Protospacer
******************************

22. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MH973663 (Streptococcus phage SW24, complete genome) position: , mismatch: 1, identity: 0.968

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
tttgtcggaaaaaattgaaaaaatcgataac	Protospacer
******************************

23. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MH937471 (Streptococcus phage CHPC927, complete genome) position: , mismatch: 1, identity: 0.968

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
tatgtcggaaaaaattgaaaaaatcgataaa	Protospacer
* *****************************

24. spacer 2.17|1245655|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448706 (Streptococcus phage Javan221, complete genome) position: , mismatch: 1, identity: 0.967

gaggtatttcaagacaagaactgcttacac	CRISPR spacer
gaggtatttcaagacaagaactacttacac	Protospacer
**********************.*******

25. spacer 2.17|1245655|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448878 (Streptococcus phage Javan224, complete genome) position: , mismatch: 1, identity: 0.967

gaggtatttcaagacaagaactgcttacac	CRISPR spacer
gaggtatttcaagacaagaactacttacac	Protospacer
**********************.*******

26. spacer 1.1|1243487|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448873 (Streptococcus phage Javan202, complete genome) position: , mismatch: 2, identity: 0.933

gaatttgaagaagaccattgttatgccgtc	CRISPR spacer
gaacttgaagaagaccattgttatgccgtt	Protospacer
***.*************************.

27. spacer 2.4|1244795|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448899 (Streptococcus phage Javan288, complete genome) position: , mismatch: 2, identity: 0.933

ccttgtcttgtaggaccgatatgtccttac	CRISPR spacer
ccttgttttgtaggaccgatatgtccttgc	Protospacer
******.*********************.*

28. spacer 2.4|1244795|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MH937498 (Streptococcus phage CHPC1057, complete genome) position: , mismatch: 2, identity: 0.933

ccttgtcttgtaggaccgatatgtccttac	CRISPR spacer
ccttgtcttgtaggaccgatatatcattac	Protospacer
**********************.** ****

29. spacer 2.4|1244795|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NC_007019 (Streptococcus phage 2972, complete genome) position: , mismatch: 2, identity: 0.933

ccttgtcttgtaggaccgatatgtccttac	CRISPR spacer
ccttgtcttgtaggaccgatatatcattac	Protospacer
**********************.** ****

30. spacer 2.4|1244795|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to AY699705 (Streptococcus thermophilus bacteriophage 2972, complete genome) position: , mismatch: 2, identity: 0.933

ccttgtcttgtaggaccgatatgtccttac	CRISPR spacer
ccttgtcttgtaggaccgatatatcattac	Protospacer
**********************.** ****

31. spacer 2.4|1244795|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448705 (Streptococcus phage Javan215, complete genome) position: , mismatch: 2, identity: 0.933

ccttgtcttgtaggaccgatatgtccttac	CRISPR spacer
ccttatcttgtaggaccgatatatccttac	Protospacer
****.*****************.*******

32. spacer 2.4|1244795|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MH937484 (Streptococcus phage CHPC1008, complete genome) position: , mismatch: 2, identity: 0.933

ccttgtcttgtaggaccgatatgtccttac	CRISPR spacer
ccttgtcttgtaggaccgatatatcattac	Protospacer
**********************.** ****

33. spacer 2.4|1244795|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448875 (Streptococcus phage Javan210, complete genome) position: , mismatch: 2, identity: 0.933

ccttgtcttgtaggaccgatatgtccttac	CRISPR spacer
ccttatcttgtaggactgatatgtccttac	Protospacer
****.***********.*************

34. spacer 2.8|1245060|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448899 (Streptococcus phage Javan288, complete genome) position: , mismatch: 2, identity: 0.933

agcgaatgcttgacggttatttaaacctgc	CRISPR spacer
ggcgaacgcttgacggttatttaaacctgc	Protospacer
.*****.***********************

35. spacer 2.5|1244861|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448705 (Streptococcus phage Javan215, complete genome) position: , mismatch: 3, identity: 0.9

cagggccaaggtcatgaataacctgcaagt	CRISPR spacer
cagggccaaggtcatgaatgacctgtaaat	Protospacer
*******************.*****.**.*

36. spacer 2.4|1244795|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448873 (Streptococcus phage Javan202, complete genome) position: , mismatch: 4, identity: 0.867

ccttgtcttgtaggaccgatatgtccttac	CRISPR spacer
ctttatcttgtaggactgatatgtccttgc	Protospacer
*.**.***********.***********.*

37. spacer 1.1|1243487|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031600 (Roseovarius indicus strain DSM 26383 plasmid pRIdsm_02, complete sequence) position: , mismatch: 5, identity: 0.833

gaatttgaagaagaccattgttat-gccgtc	CRISPR spacer
gaatttgaaggacaccattgttatcggtgt-	Protospacer
**********.* *********** * .**

38. spacer 2.5|1244861|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448721 (Streptococcus phage Javan263, complete genome) position: , mismatch: 5, identity: 0.833

cagggccaaggtcatgaataacctgcaagt	CRISPR spacer
cctgaccaaggtcatgaatgacctgtaagt	Protospacer
*  *.**************.*****.****

39. spacer 2.5|1244861|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448890 (Streptococcus phage Javan264, complete genome) position: , mismatch: 5, identity: 0.833

cagggccaaggtcatgaataacctgcaagt	CRISPR spacer
cctgaccaaggtcatgaatgacctgtaagt	Protospacer
*  *.**************.*****.****

40. spacer 2.16|1245589|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015592 (Bacillus cereus strain AR156 plasmid pAR460, complete sequence) position: , mismatch: 5, identity: 0.833

ttgaaaatctttctctttaatgc-aatatca	CRISPR spacer
gagaaaatctttatctttaattcaaatatc-	Protospacer
  ********** ******** * ******

41. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to AP023037 (Helicobacter suis NHP19-0020 plasmid pNHP190020_1 DNA, complete genome) position: , mismatch: 6, identity: 0.806

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
ttggaaggaaaaatttgaaaaaatcgttaac	Protospacer
** *  ******* ************ ***

42. spacer 2.10|1245193|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448874 (Streptococcus phage Javan206, complete genome) position: , mismatch: 6, identity: 0.8

agaaaggcaaaaccatgaaatttaatgaat	CRISPR spacer
aaaggtgaaaaacaatgaaatttaatgaat	Protospacer
*.*.. * ***** ****************

43. spacer 2.10|1245193|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448875 (Streptococcus phage Javan210, complete genome) position: , mismatch: 6, identity: 0.8

agaaaggcaaaaccatgaaatttaatgaat	CRISPR spacer
aaaggtggaaaacaatgaaatttaatgaat	Protospacer
*.*.. * ***** ****************

44. spacer 2.16|1245589|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KX258624 (Bacillus thuringiensis strain INTA Fr7-4 plasmid pFR260, complete sequence) position: , mismatch: 6, identity: 0.8

ttgaaaatctttctctttaatgcaatatca	CRISPR spacer
atgaaaatctttctctttaatgacatgttt	Protospacer
 *********************  **.*.

45. spacer 1.7|1243885|31|NZ_CP046628|CRISPRCasFinder,CRT matches to NZ_CP016179 (Vibrio breoganii strain FF50 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.774

caccgccattgacatagaaaaggaggctcca	CRISPR spacer
caaggcaattgtcatagaaaaggaggcttag	Protospacer
**  ** **** ****************. .

46. spacer 2.1|1244595|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to AP013397 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-U-MedDCM-OCT-S25-C46) position: , mismatch: 7, identity: 0.774

tgtgcagcattagcttttgagacagcgctgt	CRISPR spacer
tctgcagcattagcttttgatacaacattac	Protospacer
* ****************** ***.*..*..

47. spacer 2.1|1244595|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013691 (Myroides odoratimimus strain PR63039 plasmid p63039, complete sequence) position: , mismatch: 7, identity: 0.774

tgtgcagcattagcttttgagacagc-gctgt	CRISPR spacer
aaagcagcattagctgttaagacagctggtg-	Protospacer
 . ************ **.******* * **

48. spacer 2.1|1244595|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013691 (Myroides odoratimimus strain PR63039 plasmid p63039, complete sequence) position: , mismatch: 7, identity: 0.774

tgtgcagcattagcttttgagacagc-gctgt	CRISPR spacer
aaagcagcattagctgttaagacagctggtg-	Protospacer
 . ************ **.******* * **

49. spacer 2.2|1244662|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448707 (Streptococcus phage Javan227, complete genome) position: , mismatch: 7, identity: 0.767

actgcgtagttcggataagcagccatccat	CRISPR spacer
acattatagtctggataagcagccatccaa	Protospacer
**  ..****..*****************

50. spacer 2.2|1244662|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448879 (Streptococcus phage Javan226, complete genome) position: , mismatch: 7, identity: 0.767

actgcgtagttcggataagcagccatccat	CRISPR spacer
acattatagtctggataagcagccatccaa	Protospacer
**  ..****..*****************

51. spacer 2.5|1244861|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448932 (Streptococcus phage Javan42, complete genome) position: , mismatch: 7, identity: 0.767

cagggccaaggtcatgaataacctgcaagt	CRISPR spacer
catcacctaggtcatggataacctgcaaac	Protospacer
**  .** ********.***********..

52. spacer 2.5|1244861|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448669 (Streptococcus phage Javan11, complete genome) position: , mismatch: 7, identity: 0.767

cagggccaaggtcatgaataacctgcaagt	CRISPR spacer
catcacctaggtcatggataacctgcaaac	Protospacer
**  .** ********.***********..

53. spacer 2.5|1244861|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MN694727 (Marine virus AFVG_250M275, complete genome) position: , mismatch: 7, identity: 0.767

cagggccaaggtcatgaataacctgcaagt---	CRISPR spacer
cagggccaaggtcatggataa---acaaacctc	Protospacer
****************.****   .***..

54. spacer 2.8|1245060|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NC_049510 (Erwinia phage phiEaP-8, complete genome) position: , mismatch: 7, identity: 0.767

agcgaatgcttgacggttatttaaacctgc	CRISPR spacer
tacccatgcttgacggttagttaaccctgt	Protospacer
 .*  ************** **** ****.

55. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040803 (Streptococcus salivarius strain LAB813 plasmid pSAL813, complete sequence) position: , mismatch: 7, identity: 0.774

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
caatccggaaaatattgaaaaaatagataaa	Protospacer
.   .******* *********** ******

56. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448711 (Streptococcus phage Javan235, complete genome) position: , mismatch: 7, identity: 0.774

--tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
aactgat--gaacaaattgaaaaaatcgaaaaa	Protospacer
  .* .*  *** **************** ***

57. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MN694457 (Marine virus AFVG_250M832, complete genome) position: , mismatch: 7, identity: 0.774

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
tttaatcaaaaaaattgaagaaatcaataaa	Protospacer
***. . .***********.*****.*****

58. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MN693808 (Marine virus AFVG_250M831, complete genome) position: , mismatch: 7, identity: 0.774

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
tttaatcaaaaaaattgaagaaatcaataaa	Protospacer
***. . .***********.*****.*****

59. spacer 2.10|1245193|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 7, identity: 0.767

agaaaggcaaaaccatgaaatttaatgaat	CRISPR spacer
gtaaaggcaaaattatgaaatttaattgaa	Protospacer
. **********..************ .*

60. spacer 2.10|1245193|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK765588 (Tortoise microvirus 38 isolate 38_SP_76, complete genome) position: , mismatch: 7, identity: 0.767

agaaaggcaaaaccatgaaatttaatgaat	CRISPR spacer
cgaaaggcaaagccatgaaattcgatccgt	Protospacer
 **********.**********..**  .*

61. spacer 2.12|1245325|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to GU071094 (Synechococcus phage S-SM1, complete genome) position: , mismatch: 7, identity: 0.767

agcgtattagcgagttggttaaaactggtg	CRISPR spacer
agcgtattggcgagtttgttaaaatggaaa	Protospacer
********.******* *******. *. .

62. spacer 2.13|1245391|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to HG818824 (Citrobacter phage CR8 complete genome) position: , mismatch: 7, identity: 0.767

gctgggatgacgcaggaagaacttgcgaat	CRISPR spacer
gctgggatgactgaggaagaacttctggtc	Protospacer
***********  *********** .*. .

63. spacer 2.14|1245457|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to KC954775 (UNVERIFIED: Cronobacter phage S13, complete genome) position: , mismatch: 7, identity: 0.767

cttcctaagttgttattcgatagtttgatt	CRISPR spacer
tgaacgaagttgtccttcgatagtttgatt	Protospacer
.   * *******. ***************

64. spacer 2.14|1245457|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NC_028773 (Cronobacter phage S13, complete genome) position: , mismatch: 7, identity: 0.767

cttcctaagttgttattcgatagtttgatt	CRISPR spacer
tgaacgaagttgtccttcgatagtttgatt	Protospacer
.   * *******. ***************

65. spacer 2.16|1245589|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014284 (Bacillus thuringiensis strain Bt185 plasmid pBT1850294, complete sequence) position: , mismatch: 7, identity: 0.767

ttgaaaatctttctctttaatgcaatatca	CRISPR spacer
atgaaaatctttctctttcatgacatgttt	Protospacer
 ***************** ***  **.*.

66. spacer 2.16|1245589|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011350 (Bacillus thuringiensis strain YC-10 plasmid pYC1, complete sequence) position: , mismatch: 7, identity: 0.767

ttgaaaatctttctctttaatgcaatatca	CRISPR spacer
atgaaaatctttctctttcatgacatgttt	Protospacer
 ***************** ***  **.*.

67. spacer 2.16|1245589|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013056 (Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-1, complete sequence) position: , mismatch: 7, identity: 0.767

ttgaaaatctttctctttaatgcaatatca	CRISPR spacer
atgaaaatctttctctttcatgacatgttt	Protospacer
 ***************** ***  **.*.

68. spacer 2.16|1245589|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032609 (Bacillus thuringiensis strain QZL38 plasmid p.2, complete sequence) position: , mismatch: 7, identity: 0.767

ttgaaaatctttctctttaatgcaatatca	CRISPR spacer
atgaaaatctttctctttcatgacatgttt	Protospacer
 ***************** ***  **.*.

69. spacer 2.16|1245589|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014866 (Bacillus thuringiensis serovar tolworthi strain Pasteur Institute Standard strain plasmid pKK2, complete sequence) position: , mismatch: 7, identity: 0.767

ttgaaaatctttctctttaatgcaatatca	CRISPR spacer
atgaaaatctttctctttcatgacatgttt	Protospacer
 ***************** ***  **.*.

70. spacer 2.16|1245589|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP004876 (Bacillus thuringiensis serovar kurstaki str. HD-1 plasmid pBMB299, complete sequence) position: , mismatch: 7, identity: 0.767

ttgaaaatctttctctttaatgcaatatca	CRISPR spacer
atgaaaatctttctctttcatgacatgttt	Protospacer
 ***************** ***  **.*.

71. spacer 2.16|1245589|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NC_017203 (Bacillus thuringiensis serovar chinensis CT-43 plasmid pCT281, complete sequence) position: , mismatch: 7, identity: 0.767

ttgaaaatctttctctttaatgcaatatca	CRISPR spacer
atgaaaatctttctctttcatgacatgttt	Protospacer
 ***************** ***  **.*.

72. spacer 2.16|1245589|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NC_020384 (Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-285, complete sequence) position: , mismatch: 7, identity: 0.767

ttgaaaatctttctctttaatgcaatatca	CRISPR spacer
atgaaaatctttctctttcatgacatgttt	Protospacer
 ***************** ***  **.*.

73. spacer 2.16|1245589|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015152 (Bacillus thuringiensis strain Bc601 plasmid pBTBC2, complete sequence) position: , mismatch: 7, identity: 0.767

ttgaaaatctttctctttaatgcaatatca	CRISPR spacer
atgaaaatctttctctttcatgacatgttt	Protospacer
 ***************** ***  **.*.

74. spacer 2.16|1245589|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP004861 (Bacillus thuringiensis serovar kurstaki str. YBT-1520 plasmid pBMB293, complete sequence) position: , mismatch: 7, identity: 0.767

ttgaaaatctttctctttaatgcaatatca	CRISPR spacer
atgaaaatctttctctttcatgacatgttt	Protospacer
 ***************** ***  **.*.

75. spacer 2.16|1245589|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010111 (Bacillus thuringiensis serovar indiana strain HD521 plasmid pBTHD521-5, complete sequence) position: , mismatch: 7, identity: 0.767

ttgaaaatctttctctttaatgcaatatca	CRISPR spacer
atgaaaatctttctctttcatgacatgttt	Protospacer
 ***************** ***  **.*.

76. spacer 2.16|1245589|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010091 (Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB267, complete sequence) position: , mismatch: 7, identity: 0.767

ttgaaaatctttctctttaatgcaatatca	CRISPR spacer
atgaaaatctttctctttcatgacatgttt	Protospacer
 ***************** ***  **.*.

77. spacer 1.1|1243487|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MH363700 (Vibrio phage VP-1, complete genome) position: , mismatch: 8, identity: 0.733

gaatttgaagaagaccattgttatgccgtc--	CRISPR spacer
tgatttgaagacgaccattgtta--acaacaa	Protospacer
 .********* ***********   *. *

78. spacer 1.1|1243487|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NC_048765 (Vibrio phage VAP7, complete genome) position: , mismatch: 8, identity: 0.733

gaatttgaagaagaccattgttatgccgtc--	CRISPR spacer
tgatttgaagacgaccattgtta--acaacaa	Protospacer
 .********* ***********   *. *

79. spacer 1.4|1243685|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054718 (Salmonella enterica strain 85-0120 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

tcactttatatggataagcgtgctctagat-----	CRISPR spacer
tcactttacatggataagcg-----taagtatcgc	Protospacer
********.***********     **..*

80. spacer 1.4|1243685|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054718 (Salmonella enterica strain 85-0120 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

tcactttatatggataagcgtgctctagat-----	CRISPR spacer
tcactttacatggataagcg-----taagtatcgc	Protospacer
********.***********     **..*

81. spacer 1.4|1243685|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NC_049466 (Escherichia phage vB_EcoM_4HA13, complete genome) position: , mismatch: 8, identity: 0.733

tcactttatatggataagcgtgctctagat	CRISPR spacer
gaacttgatatcgataagcgtgctcatggc	Protospacer
  **** **** *************  *..

82. spacer 1.5|1243751|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019532 (Serratia symbiotica strain IS plasmid pSsyis1, complete sequence) position: , mismatch: 8, identity: 0.742

taaataggaacggtttttctattgacttaaa	CRISPR spacer
tcatacttaacggtttttacattgacttaaa	Protospacer
* *     ********** .***********

83. spacer 1.6|1243818|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019532 (Serratia symbiotica strain IS plasmid pSsyis1, complete sequence) position: , mismatch: 8, identity: 0.742

taaataggaacggtttttctattgacttaaa	CRISPR spacer
tcatacttaacggtttttacattgacttaaa	Protospacer
* *     ********** .***********

84. spacer 1.7|1243885|31|NZ_CP046628|CRISPRCasFinder,CRT matches to KF147891 (Pseudomonas phage PaBG, complete genome) position: , mismatch: 8, identity: 0.742

caccgccattgacatagaaaaggaggctcca	CRISPR spacer
caccgccattgacagagaacaggagctctgg	Protospacer
************** **** ***** ... .

85. spacer 2.7|1244993|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MN648195 (Acinetobacter phage Konradin, complete genome) position: , mismatch: 8, identity: 0.742

aaatcgtcttcgttgatatccatagggctag	CRISPR spacer
aaatcgtcttcgttgatattcaattacctca	Protospacer
*******************.**   . ** .

86. spacer 2.7|1244993|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MT385367 (Acinetobacter phage Abraxas, complete genome) position: , mismatch: 8, identity: 0.742

aaatcgtcttcgttgatatccatagggctag	CRISPR spacer
aaatcgtcttcgttgatattcaattacctca	Protospacer
*******************.**   . ** .

87. spacer 2.7|1244993|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MN662249 (Acinetobacter phage Stupor, complete genome) position: , mismatch: 8, identity: 0.742

aaatcgtcttcgttgatatccatagggctag	CRISPR spacer
aaatcgtcttcgttgatattcaattacctca	Protospacer
*******************.**   . ** .

88. spacer 2.7|1244993|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NC_049493 (Acinetobacter phage vB_AbaP_Lazarus, complete genome) position: , mismatch: 8, identity: 0.742

aaatcgtcttcgttgatatccatagggctag	CRISPR spacer
aaatcgtcttcgttgatattcaattacctca	Protospacer
*******************.**   . ** .

89. spacer 2.7|1244993|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MN782535 (Acinetobacter phage Lazarus, complete genome) position: , mismatch: 8, identity: 0.742

aaatcgtcttcgttgatatccatagggctag	CRISPR spacer
aaatcgtcttcgttgatattcaattacctca	Protospacer
*******************.**   . ** .

90. spacer 2.7|1244993|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NC_049479 (Acinetobacter phage vB_AbaP_Konradin, complete genome) position: , mismatch: 8, identity: 0.742

aaatcgtcttcgttgatatccatagggctag	CRISPR spacer
aaatcgtcttcgttgatattcaattacctca	Protospacer
*******************.**   . ** .

91. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024404 (Borrelia miyamotoi strain Izh-4 plasmid pIzh4-lp13, complete sequence) position: , mismatch: 8, identity: 0.742

-----tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
gaatcttc-----aaaaaattgaaaaaatcgacaag	Protospacer
     **.     *******************.**.

92. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024220 (Borrelia miyamotoi strain Izh-5 plasmid pIzh5-12) position: , mismatch: 8, identity: 0.742

-----tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
gaatcttc-----aaaaaattgaaaaaatcgacaag	Protospacer
     **.     *******************.**.

93. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024343 (Borrelia miyamotoi strain Yekat-1 plasmid pYkt1-8) position: , mismatch: 8, identity: 0.742

-----tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
gaatcttc-----aaaaaattgaaaaaatcgacaag	Protospacer
     **.     *******************.**.

94. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024365 (Borrelia miyamotoi strain Izh-16 plasmid pIzh16-10) position: , mismatch: 8, identity: 0.742

-----tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
gaatcttc-----aaaaaattgaaaaaatcgacaag	Protospacer
     **.     *******************.**.

95. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024386 (Borrelia miyamotoi strain Izh-14 plasmid pIzh14-11) position: , mismatch: 8, identity: 0.742

-----tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
gaatcttc-----aaaaaattgaaaaaatcgacaag	Protospacer
     **.     *******************.**.

96. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NC_014628 (Paenibacillus polymyxa SC2 plasmid pSC2, complete sequence) position: , mismatch: 8, identity: 0.742

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
attggcggaaaaaattgaagaaattattagt	Protospacer
 *** **************.****.. **.

97. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MT430910 (Streptococcus phage smHBZ8, complete genome) position: , mismatch: 8, identity: 0.742

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
gattacagaaataattgaaaaaatcgaaaac	Protospacer
  *  *.**** *************** **

98. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MN938931 (Streptococcus phage D4446, complete genome) position: , mismatch: 8, identity: 0.742

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
gaggttcgaagaaattgaaaaaatcgaaaac	Protospacer
   **. ***.**************** **

99. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to AP014365 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S41-C61, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 8, identity: 0.742

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
aaaatctaaaaaaattgaaaaattagataaa	Protospacer
   .** .************** * ******

100. spacer 2.13|1245391|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021525 (Acetobacter ascendens strain SRCM101447 plasmid pAP1447-1) position: , mismatch: 8, identity: 0.733

gctgggatgacgcaggaagaacttgcgaat	CRISPR spacer
cttgggctgacgcaggaagaaattgccttc	Protospacer
 .**** ************** ****   .

101. spacer 2.13|1245391|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024882 (Citrobacter freundii strain AR_0022 plasmid unitig_1_pilon, complete sequence) position: , mismatch: 8, identity: 0.733

gctgggatgacgcaggaagaacttgcgaat	CRISPR spacer
ggcttcatgacgcaggatgaacttgccaag	Protospacer
* .   *********** ******** **

102. spacer 2.13|1245391|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032180 (Citrobacter freundii strain AR_0116 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

gctgggatgacgcaggaagaacttgcgaat	CRISPR spacer
ggcttcatgacgcaggatgaacttgccaag	Protospacer
* .   *********** ******** **

103. spacer 2.13|1245391|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP037863 (Citrobacter sp. LY-1 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

gctgggatgacgcaggaagaacttgcgaat	CRISPR spacer
ggcttcatgacgcaggatgaacttgccaag	Protospacer
* .   *********** ******** **

104. spacer 2.16|1245589|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020081 (Vibrio campbellii strain 20130629003S01 plasmid pVCGX4, complete sequence) position: , mismatch: 8, identity: 0.733

ttgaaaatctttctctttaatgcaatatca	CRISPR spacer
taataaatctttctctttattgctataagg	Protospacer
* . *************** *** ***  .

105. spacer 2.16|1245589|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019297 (Vibrio campbellii strain LMB29 plasmid pLMB99, complete sequence) position: , mismatch: 8, identity: 0.733

ttgaaaatctttctctttaatgcaatatca	CRISPR spacer
taataaatctttctctttattgctataagg	Protospacer
* . *************** *** ***  .

106. spacer 2.16|1245589|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019297 (Vibrio campbellii strain LMB29 plasmid pLMB99, complete sequence) position: , mismatch: 8, identity: 0.733

ttgaaaatctttctctttaatgcaatatca	CRISPR spacer
taataaatctttctctttattgctataagg	Protospacer
* . *************** *** ***  .

107. spacer 2.17|1245655|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MN694111 (Marine virus AFVG_250M218, complete genome) position: , mismatch: 8, identity: 0.733

gaggtatttcaagacaagaactgcttacac	CRISPR spacer
taggtatatcaagaaaagaactgcacatgg	Protospacer
 ****** ****** ********* .*..

108. spacer 1.3|1243619|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023002 (Bacillus anthracis strain 14RA5914 plasmid pX01, complete sequence) position: , mismatch: 9, identity: 0.7

aataaagcagagtaccaaatagattacagt	CRISPR spacer
ttataagtagagtagcaaatagattactaa	Protospacer
    ***.****** ************ .

109. spacer 2.6|1244927|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to AP014011 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C79-MedDCM-OCT-S38-C32, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.7

cgactttagccgttgccattgtcggaataa	CRISPR spacer
atccttgagccgttgccattgccggaggtg	Protospacer
   *** **************.****.  .

110. spacer 2.6|1244927|30|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to AP013546 (Uncultured phage_MedDCM-OCT-S37-C6 DNA, complete genome, group G9, isolate: uvMED-CGR-C79-MedDCM-OCT-S37-C6) position: , mismatch: 9, identity: 0.7

cgactttagccgttgccattgtcggaataa	CRISPR spacer
atccttgagccgttgccattgccggaggtg	Protospacer
   *** **************.****.  .

111. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to MK448901 (Streptococcus phage Javan306, complete genome) position: , mismatch: 9, identity: 0.71

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
cgcttcggaaaaaattgaaaaattcaatttg	Protospacer
. . ****************** **.**  .

112. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014152 (Clostridium botulinum strain BrDura plasmid pRSJ20_1, complete sequence) position: , mismatch: 9, identity: 0.71

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
taatcttaaaaaaattgaaaaaatcaaaaaa	Protospacer
*   .. .*****************.* ***

113. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024773 (Bacillus thuringiensis LM1212 plasmid pLM2, complete sequence) position: , mismatch: 9, identity: 0.71

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
gaaaaagaaaaagattgaaaacatcgataaa	Protospacer
   .  *.****.******** *********

114. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013710 (Clostridium botulinum strain F634 plasmid pRSJ2_3, complete sequence) position: , mismatch: 9, identity: 0.71

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
taatcttaaaaaaattgaaaaaatcaaaaaa	Protospacer
*   .. .*****************.* ***

115. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NC_010418 (Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence) position: , mismatch: 9, identity: 0.71

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
taatcttaaaaaaattgaaaaaatcaaaaaa	Protospacer
*   .. .*****************.* ***

116. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042422 (Leuconostoc lactis strain CBA3622 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.71

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
cgttcgcaaaaatattgaagaaatcgataaa	Protospacer
. * .  .**** ******.***********

117. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042423 (Leuconostoc lactis strain CBA3622 plasmid unnamed3) position: , mismatch: 9, identity: 0.71

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
cgttcgcaaaaatattgaagaaatcgataaa	Protospacer
. * .  .**** ******.***********

118. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042423 (Leuconostoc lactis strain CBA3622 plasmid unnamed3) position: , mismatch: 9, identity: 0.71

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
cgttcgcaaaaatattgaagaaatcgataaa	Protospacer
. * .  .**** ******.***********

119. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042423 (Leuconostoc lactis strain CBA3622 plasmid unnamed3) position: , mismatch: 9, identity: 0.71

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
cgttcgcaaaaatattgaagaaatcgataaa	Protospacer
. * .  .**** ******.***********

120. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041075 (Bacillus tropicus strain LM1212-W3 plasmid p2, complete sequence) position: , mismatch: 9, identity: 0.71

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
gaaaaagaaaaagattgaaaacatcgataaa	Protospacer
   .  *.****.******** *********

121. spacer 2.9|1245126|31|NZ_CP046628|PILER-CR,CRISPRCasFinder,CRT matches to JN638751 (Bacillus phage G, complete genome) position: , mismatch: 9, identity: 0.71

tttgtcggaaaaaattgaaaaaatcgataaa	CRISPR spacer
agtaaatgaaaaaattgaaaaaattaataat	Protospacer
  *.   *****************..****

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

160069 : 169370

Bacillus_virus(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039691936.1\|160069_161407_-	aminopeptidase C	R4TV59	Phaeocystis_globosa_virus	1.7e-66	34.2
WP_039691935.1\|161660_162485_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	3.7e-75	56.4
WP_024344638.1\|162484_163945_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	8.5e-99	41.6
WP_003067371.1\|164172_165087_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	1.2e-87	53.7
WP_003067372.1\|165153_165378_-	DUF4059 family protein	NA	NA	NA	NA
WP_027968121.1\|165459_166203_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.1e-29	39.6
WP_045798190.1\|166202_167006_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_157339053.1\|167037_167862_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_157339054.1\|168026_169370_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	3.2e-44	29.7

DBSCAN-SWA_2

571083 : 583402

Erysipelothrix_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157339178.1\|571083_573798_-	AAA family ATPase	A0A2K5B264	Erysipelothrix_phage	1.5e-189	42.2
WP_021141392.1\|573907_575455_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	1.5e-48	53.9
WP_033152112.1\|575525_576077_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.9e-23	36.3
WP_157339179.1\|576076_577096_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	8.9e-63	43.9
WP_074451192.1\|577131_578076_-	orotidine-5'-phosphate decarboxylase	NA	NA	NA	NA
WP_039696059.1\|578103_579567_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.1e-56	34.7
WP_157339180.1\|579676_583402_-	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	2.4e-36	25.4

DBSCAN-SWA_3

634892 : 643014

Streptococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033153614.1\|634892_636137_+	insulinase family protein	A0A1X9I714	Streptococcus_phage	1.5e-91	43.4
WP_157339189.1\|636137_637427_+	insulinase family protein	K7Z7Q1	Megavirus	1.2e-19	28.5
WP_074639567.1\|637493_638423_+	hypothetical protein	NA	NA	NA	NA
WP_004233663.1\|638432_638987_+	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_024344467.1\|638983_639826_+	energy-coupling factor transporter ATPase	G9BWD6	Planktothrix_phage	2.9e-19	31.4
WP_074451154.1\|639801_640644_+	energy-coupling factor transporter ATPase	W6JKT0	Anomala_cuprea_entomopoxvirus	5.2e-16	29.0
WP_033153608.1\|640636_641434_+	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_024344464.1\|641571_642165_+	LysM peptidoglycan-binding domain-containing protein	A0A096XT26	Enterococcus_phage	2.8e-24	48.1
WP_024344463.1\|642378_643014_+	transglycosylase SLT domain-containing protein	Q4Z8Z7	Staphylococcus_phage	4.5e-20	76.6

DBSCAN-SWA_4

1018857 : 1028596

Streptococcus_phage(75.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021142936.1\|1018857_1019622_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.5e-17	24.8
WP_024343676.1\|1019621_1020332_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.4e-14	27.0
WP_027968438.1\|1020439_1021099_+	CBS domain-containing protein	M1NSC5	Streptococcus_phage	9.8e-71	62.8
WP_021142933.1\|1021188_1021821_+	dTMP kinase	M1PSC7	Streptococcus_phage	3.2e-71	65.7
WP_157327162.1\|1021834_1022710_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	8.2e-73	49.3
WP_033153166.1\|1022706_1023507_+	signal peptidase II	NA	NA	NA	NA
WP_004232930.1\|1023499_1023820_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	9.1e-30	62.3
WP_027968441.1\|1023832_1024696_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	2.1e-121	76.3
WP_021142928.1\|1025017_1026253_+	ammonium transporter	NA	NA	NA	NA
WP_024343682.1\|1026284_1026626_+	P-II family nitrogen regulator	NA	NA	NA	NA
WP_074639465.1\|1026739_1027369_-	copper homeostasis protein CutC	NA	NA	NA	NA
WP_024343683.1\|1027504_1028596_+	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	3.5e-174	82.0

DBSCAN-SWA_5

1092362 : 1115234

Streptococcus_phage(78.26%)

integrase

attL 1084226:1084240|attR 1116061:1116075

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1084226:1084240	attL	NA	NA	NA	NA
WP_024343734.1\|1092362_1093127_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.4e-39	43.8
WP_021142846.1\|1093434_1094145_+	response regulator transcription factor	W8CYM9	Bacillus_phage	2.2e-39	39.0
WP_024343735.1\|1094137_1095490_+	cell wall metabolism sensor histidine kinase VicK	W8CYF6	Bacillus_phage	2.5e-36	34.4
WP_157339348.1\|1095490_1096300_+	MBL fold metallo-hydrolase	A0A2H4J3R0	uncultured_Caudovirales_phage	7.4e-36	37.0
WP_001825268.1\|1096533_1096653_+	hypothetical protein	NA	NA	NA	NA
WP_000420682.1\|1096675_1096990_+	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
WP_157339349.1\|1097005_1097392_+	DUF961 domain-containing protein	A0A1S5SF96	Streptococcus_phage	1.2e-63	99.2
WP_000813488.1\|1097420_1098806_+	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000879507.1\|1098808_1098961_+	hypothetical protein	NA	NA	NA	NA
WP_000398284.1\|1098983_1100189_+	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
WP_001009056.1\|1100231_1100453_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000342539.1\|1100569_1101067_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
WP_000506270.1\|1101041_1101548_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_000331160.1\|1101531_1103979_+	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
WP_000804748.1\|1103981_1106159_+	membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
WP_000769868.1\|1106155_1107157_+	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
WP_157339350.1\|1107153_1108086_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	1.7e-156	91.3
WP_011058339.1\|1108360_1108447_+	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_157339351.1\|1108462_1110382_+	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	96.6
WP_011058338.1\|1110482_1110668_+	conjugal transfer protein	D0R0F6	Streptococcus_phage	3.9e-17	67.9
WP_001227347.1\|1110727_1111081_-	helix-turn-helix transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
WP_013670292.1\|1111285_1111357_+	hypothetical protein	NA	NA	NA	NA
WP_000804885.1\|1111585_1112008_+	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
WP_000857133.1\|1112004_1112235_+	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
WP_001845478.1\|1112460_1112712_-	hypothetical protein	NA	NA	NA	NA
WP_000814511.1\|1112695_1112899_+	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
WP_157339352.1\|1112980_1114198_+\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	6.4e-233	99.8
WP_021142842.1\|1114547_1115234_+	ribonuclease III	M4QMG4	Micromonas_pusilla_virus	8.5e-25	35.1
1116061:1116075	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1132704 : 1141008

Phage_TP(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039691683.1\|1132704_1133994_+	U32 family peptidase	Q6DW11	Phage_TP	5.6e-38	30.1
WP_142349230.1\|1134050_1134386_-	hypothetical protein	NA	NA	NA	NA
WP_004232736.1\|1134491_1134704_+	hypothetical protein	A0A223LEC3	Bacillus_phage	5.1e-13	53.1
WP_157339359.1\|1134822_1135575_+	HAD hydrolase-like protein	NA	NA	NA	NA
WP_157339360.1\|1135638_1136832_-	MFS transporter	A0A2K5B2B5	Erysipelothrix_phage	4.0e-06	23.3
WP_157339361.1\|1136974_1137514_-	TetR family transcriptional regulator	A0A1X9I6A2	Streptococcus_phage	3.4e-05	40.3
WP_157339362.1\|1137653_1139423_+	DHA2 family efflux MFS transporter permease subunit	A0A0M3UL24	Mycobacterium_phage	7.8e-22	24.8
WP_021142785.1\|1139517_1141008_-\|tRNA	lysine--tRNA ligase	A0A2K9KZX5	Tupanvirus	1.6e-89	40.2

DBSCAN-SWA_7

1392331 : 1404619

Bacillus_phage(22.22%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157339452.1\|1392331_1393537_+\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	5.4e-43	48.5
WP_157339453.1\|1393533_1395402_+	ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	7.9e-65	32.5
WP_027968630.1\|1395446_1397186_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.4e-12	29.8
WP_157339454.1\|1397188_1398958_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	2.3e-58	30.3
WP_004232125.1\|1399123_1399777_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	2.0e-60	53.5
WP_027968631.1\|1399776_1400223_+	6-carboxytetrahydropterin synthase QueD	J9PV91	Bacillus_phage	2.1e-45	58.2
WP_157339455.1\|1400215_1400929_+	7-carboxy-7-deazaguanine synthase QueE	E7DN68	Pneumococcus_phage	5.6e-64	48.4
WP_021142478.1\|1400943_1401435_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	7.4e-47	62.3
WP_157339456.1\|1401473_1401971_-	DUF308 domain-containing protein	NA	NA	NA	NA
WP_021142476.1\|1402200_1403550_+	NADP-specific glutamate dehydrogenase	NA	NA	NA	NA
WP_157339457.1\|1403702_1404206_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_157339458.1\|1404208_1404619_+	peptide deformylase	A0A2I7QLT9	Vibrio_phage	4.9e-12	38.9

DBSCAN-SWA_8

1599468 : 1613689

Streptococcus_phage(44.44%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039698256.1\|1599468_1600167_-	GntR family transcriptional regulator	A0A2H5BLU5	Streptomyces_phage	2.0e-05	36.7
WP_157339548.1\|1600260_1600824_-	hypothetical protein	NA	NA	NA	NA
WP_157339549.1\|1600835_1602230_-	AAA family ATPase	A0A2I7RNF1	Vibrio_phage	1.6e-17	22.4
WP_157339550.1\|1602230_1606598_-	DEAD/DEAH box helicase family protein	A0A1V0SII8	Klosneuvirus	4.9e-25	21.7
WP_033152588.1\|1606602_1607280_-	hypothetical protein	A0A2H4YF91	Aeromonas_phage	1.4e-08	34.0
WP_157339551.1\|1607593_1607953_-	hypothetical protein	E4ZFJ1	Streptococcus_phage	6.8e-18	48.7
WP_111698630.1\|1607954_1609370_-	Y-family DNA polymerase	M1Q231	Streptococcus_phage	1.3e-200	73.0
WP_157339552.1\|1609370_1609574_-	hypothetical protein	D0R0A4	Streptococcus_phage	6.0e-11	47.7
WP_033152584.1\|1609575_1610262_-	helix-turn-helix transcriptional regulator	E8ZDN4	Streptococcus_phage	1.5e-58	49.6
WP_157339553.1\|1610387_1610765_-	PTS-dependent dihydroxyacetone kinase phosphotransferase subunit DhaM	NA	NA	NA	NA
WP_126437822.1\|1610757_1611348_-	dihydroxyacetone kinase subunit L	NA	NA	NA	NA
WP_157339554.1\|1611497_1612823_-	MATE family efflux transporter	NA	NA	NA	NA
WP_157339555.1\|1613086_1613689_-	repressor LexA	E5DV74	Deep-sea_thermophilic_phage	5.3e-15	32.6

DBSCAN-SWA_9

1892632 : 1900454

Staphylococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039690988.1\|1892632_1892860_+	glutaredoxin-like protein NrdH	A0A0M7REK7	Lactobacillus_phage	5.1e-11	39.0
WP_157339676.1\|1892920_1895080_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	3.0e-262	61.5
WP_074450913.1\|1895306_1896269_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	1.8e-129	70.8
WP_021141953.1\|1896513_1897080_+	energy-coupled thiamine transporter ThiT	NA	NA	NA	NA
WP_039690990.1\|1897143_1897605_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	7.4e-41	53.3
WP_157339677.1\|1897617_1898796_-	GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.6e-103	50.8
WP_074483371.1\|1898796_1899399_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	3.1e-31	37.9
WP_157339678.1\|1899398_1900454_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	7.6e-41	32.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP046628

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection