CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP040335	Bacillus cereus strain DLOU-Changhai plasmid unnamed1, complete sequence	2 crisprs	NA	0	5	2	0
NZ_CP040334	Bacillus cereus strain DLOU-Changhai chromosome, complete genome	3 crisprs	WYL,csa3,cas3,DEDDh,cas14j,DinG,cas14k,c2c10_CAS-V-U3	1	13	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP040335_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040335_1

8704-8952

Orphan

Consensus_repeat	Method
CAGGGGATTCAAGGTAATCCGGG	CRISPRCasFinder

4 spacers

The CRISPR arrays of NZ_CP040335_1

>merge|NZ_CP040335|1|8704-8952|CRISPRCasFinder
ACTGGAATTCAAGGTAGCCTGGGACCTACTGGGCCTCAAGGTATTTCTGGACCTCAAGGGATTCCTGGGATTTCTGGATCTATTGGTCCAACTGGACCTTCTGGAATTCAAGGTATCCAAGGTATCCAAGGCATTCCTGGCATTCAAGGTCCTATTGGACCCACTGGAATAACAGGGGGCACTGGAATTCAAGGGATTCCTGGCATTCAAGGGATTCAAGGGATTCAAGGGATTCAAGGGATTCCTGGT

>NZ_CP040335|1|1|8704-8952|CRISPRCasFinder
ACTGGAATTCAAGGTAGCCTGGG	ACCTACTGGGCCTCAAGGTATTTCTGGACCT
CAAGGGATTCCTGGGATTTCTGG	ATCTATTGGTCCAACTGGACCTTCTGGAATT
CAAGGTATCCAAGGTATCCAAGG	CATTCCTGGCATTCAAGGTCCTATTGGACCCACTGGAATAACAGGGGGC
ACTGGAATTCAAGGGATTCCTGG	CATTCAAGGGATTCAAGGGATT
CAAGGGATTCAAGGGATTCCTGGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040335.1\|WP_053564381.1\|5503_6046_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271192
NZ_CP040335.1\|WP_001013578.1\|6826_7015_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040335.1\|WP_157418287.1\|12716_13172_-\|nucleotide-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|212148
NZ_CP040335.1\|WP_053564380.1\|4339_5290_-\|nucleoside-hydrolase	unknown	unknown	gnl\|CDD\|238257
NZ_CP040335.1\|WP_157418288.1\|13654_14014_-\|cell-division-protein-SepF	unknown	unknown	unknown
NZ_CP040335.1\|WP_157418285.1\|2358_3528_-\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NZ_CP040335.1\|WP_157418282.1\|392_719_-\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|366837
NZ_CP040335.1\|WP_000854271.1\|15887_16079_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP040335.1\|WP_157418283.1\|722_872_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182255
NZ_CP040335.1\|WP_000109490.1\|13191_13443_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040335.1\|WP_157418289.1\|14006_14285_-\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|131898
NZ_CP040335.1\|WP_098205548.1\|10713_11169_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040335.1\|WP_157418284.1\|1250_2021_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040335.1\|WP_000166175.1\|6045_6528_-\|ArpU-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|273725
NZ_CP040335.1\|WP_000522030.1\|15565_15832_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378935
NZ_CP040335.1\|WP_000717829.1\|13468_13636_-\|DUF3954-domain-containing-protein	unknown	unknown	gnl\|CDD\|315731
NZ_CP040335.1\|WP_000130745.1\|7035_7158_-\|DUF3983-domain-containing-protein	unknown	unknown	gnl\|CDD\|289882
NZ_CP040335.1\|WP_065228892.1\|12076_12484_+\|DUF4870-domain-containing-protein	unknown	unknown	unknown
NZ_CP040335.1\|WP_157418290.1\|14288_15344_-\|DnaD-domain-protein	unknown	unknown	gnl\|CDD\|273630
NZ_CP040335.1\|WP_098683955.1\|7187_7370_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP040335.1\|WP_053564381.1\|5503_6046_-\|site-specific-integrase	gnl\|CDD\|271192	cd01192, INT_C_like_3, Uncharacterized site-specific tyrosine recombinase, C-terminal catalytic domain. Tyrosine recombinase (integrase) belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain contains six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	6.77036e-66
NZ_CP040335.1\|WP_157418287.1\|12716_13172_-\|nucleotide-pyrophosphohydrolase	gnl\|CDD\|212148	cd11541, NTP-PPase_u4, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea. This family corresponds to a group of uncharacterized hypothetical proteins from bacteria, showing a high sequence similarity to the dimeric 2-deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTP pyrophosphatase or dUTPase) and NTP-PPase MazG proteins. However, unlike typical tandem-domain MazG proteins, members in this family consist of a single MazG-like domain that contains a well conserved divalent ion-binding motif EXX[E/D].	2.4166e-32
NZ_CP040335.1\|WP_053564380.1\|4339_5290_-\|nucleoside-hydrolase	gnl\|CDD\|238257	cd00455, nuc_hydro, nuc_hydro: Nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes vary in their substrate specificity. This group contains eukaryotic, bacterial and archeal proteins similar to the inosine-uridine preferring nucleoside hydrolase from Crithidia fasciculata, the xanthosine-inosine-uridine-adenosine-preferring nucleoside hydrolase RihC from Salmonella enterica serovar Typhimurium, the purine-specific inosine-adenosine-guanosine-preferring nucleoside hydrolase from Trypanosoma vivax and, pyrimidine-specific uridine-cytidine preferring nucleoside hydrolases such as URH1 from Saccharomyces cerevisiae, RihA and RihB from Escherichia coli. Nucleoside hydrolases are of interest as a target for antiprotozoan drugs as, no nucleoside hydrolase activity or genes encoding these enzymes have been detected in humans and, parasitic protozoans lack de novo purine synthesis relying on nucleoside hydrolase to scavenge purine and/or pyrimidines from the environment. .	1.9181e-116
NZ_CP040335.1\|WP_157418285.1\|2358_3528_-\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	8.93307e-72
NZ_CP040335.1\|WP_157418282.1\|392_719_-\|HNH-endonuclease	gnl\|CDD\|366837	pfam01844, HNH, HNH endonuclease. His-Asn-His (HNH) proteins are a very common family of small nucleic acid-binding proteins that are generally associated with endonuclease activity.	9.46754e-08
NZ_CP040335.1\|WP_157418283.1\|722_872_-\|hypothetical-protein	gnl\|CDD\|182255	PRK10125, PRK10125, colanic acid biosynthesis glycosyltransferase WcaC.	9.27195e-05
NZ_CP040335.1\|WP_000854271.1\|15887_16079_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.16346e-12
NZ_CP040335.1\|WP_157418289.1\|14006_14285_-\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl\|CDD\|131898	TIGR02851, stage_V_sporulation_protein_T, stage V sporulation protein T. Members of this protein family are the stage V sporulation protein T (SpoVT), a protein of the sporulation/germination program in Bacillus subtilis and related species. The amino-terminal 50 amino acids are nearly perfectly conserved across all endospore-forming bacteria. SpoVT is a DNA-binding transcriptional regulator related to AbrB (See pfam04014). [Regulatory functions, DNA interactions, Cellular processes, Sporulation and germination].	7.68309e-11
NZ_CP040335.1\|WP_157418290.1\|14288_15344_-\|DnaD-domain-protein	gnl\|CDD\|273630	TIGR01446, replication_protein, DnaD and phage-associated domain. This model represents the conserved domain of DnaD, part of Bacillus subtilis replication restart primosome, and of a number of phage-associated proteins. Members, both chromosomal or phage-associated, are found in the Bacillus/Clostridium group of Gram-positive bacteria. [DNA metabolism, DNA replication, recombination, and repair, Mobile and extrachromosomal element functions, Prophage functions].	3.19097e-11
NZ_CP040335.1\|WP_000166175.1\|6045_6528_-\|ArpU-family-transcriptional-regulator	gnl\|CDD\|273725	TIGR01637, Putative_autolysin_regulatory_protein_ArpU, phage transcriptional regulator, ArpU family. This model represents a family of phage proteins, including ArpU, called a putative autolysin regulatory protein. ArpU was described as a regulator of cellular muramidase-2 of Enterococcus hirae but appears to have been cloned from a prophage. This family appears related to the RinA family of bacteriophage transcriptional activators and to some sporulation-specific sigma factors. We propose that this is a phage transcriptional activator family. [Mobile and extrachromosomal element functions, Prophage functions, Regulatory functions, DNA interactions].	3.05821e-16
NZ_CP040335.1\|WP_000522030.1\|15565_15832_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	1.86891e-08
NZ_CP040335.1\|WP_000717829.1\|13468_13636_-\|DUF3954-domain-containing-protein	gnl\|CDD\|315731	pfam13128, DUF3954, Protein of unknown function (DUF3954). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and viruses. Proteins in this family are approximately 60 amino acids in length.	3.77667e-15
NZ_CP040335.1\|WP_000130745.1\|7035_7158_-\|DUF3983-domain-containing-protein	gnl\|CDD\|289882	pfam13137, DUF3983, Protein of unknown function (DUF3983). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and viruses. Proteins in this family are approximately 40 amino acids in length. There is a conserved AWRN sequence motif.	1.50628e-05

>NZ_CP040335.1|WP_098683955.1|7187_7370_-|hypothetical-protein
MEGKTEPKMVPMASYGSNKEKQCVEFQLLINEEIYVMPVHERDVKGMETWFLLKKHNLIK
>NZ_CP040335.1|WP_000130745.1|7035_7158_-|DUF3983-domain-containing-protein
MTDLKKRKIRKAIARRTKAVEKYQVDNAWRNIFVKAGIIK
>NZ_CP040335.1|WP_001013578.1|6826_7015_-|hypothetical-protein
MNGKQFFGMYWALYLIIMFVTFSNAKSFIQAGIILVLVILISEVDHKYGFYKGSKKAKSNQI
>NZ_CP040335.1|WP_000166175.1|6045_6528_-|ArpU-family-transcriptional-regulator
MTKQLSFLPKIDRTATQEELEGVLESVRIHRQFGMMRKEMKVTPSYEIREHGPTHAVGKPLEDVAIANIQQSKREEWLEKMSLSIDQFLNRLGNGRAGSIQRDIIYKRYLEEEDVCDYMVYNEIGMSERTYRRWKSKAFYKLAFALGLEVYETEETGGNK
>NZ_CP040335.1|WP_053564381.1|5503_6046_-|site-specific-integrase
MNFVQPIRDSEQIQQIKEYLKEKNERNYILFVIGINTGLRISDILKLKVGDLNGSHISMREMKTGKQKRIHITAALRRELKWYIEDMEDYEYIIKSRQGKNRPIGRSMAYKILSTTAAKFGLEEIGTHTLRKTFGYHMYMQTKNIALLMEIFNHSSERVTLRYIGVNQDAMDKAMTRFKI
>NZ_CP040335.1|WP_053564380.1|4339_5290_-|nucleoside-hydrolase
MQKKVLLFTDLGIDDAFAILYTFFRKDIQLVGIVADYGNVSRENVIRNINYLKYIAGREEIPVFLGASVPLTGILIQYFPEVHGKVGLGPIIPPEISYPVYPLNDIYQIIESNLEDLTIINLGRLSSLATTFVLNLETMRNVRECICMGGAFFYPGNVTAVAEANFHADPYAANLILQHAKNLTIIPLNVTQHAIVTTEMVEQIDAFHRNTQDLAGLIIKPMLDYYYNFYSKSNPGISGSPMHDFVTVWYLLNREAVSLSRVPIKVIPDQGEGFGQSIADFRFVTNPGYKTHNVAFQFDYERFRKDIMETFLKKRV
>NZ_CP040335.1|WP_157418285.1|2358_3528_-|serine-hydrolase
MKIRSQITCASLALLIAGSSLLYTTPTSIVKAEPTQNVSSSLQTNTQRDRTSVKQAMRDTLQFGYPGILAKTSEGGKTWGYAAGIADLRTKKPMKTDFRFRIGSVTKTFTATVVLQLVGENRLKLDDHIEDWLPGVIQGNGYDGNKITIREILNHTSGIAEYSRSKDVDFTDTKKSYTAEELVKMGISLPPDFAPGKGWSYSNTGYVLLGILIEKVTGNSYAEEVENRIIEPLELSNTFLPGNSSVIPGTNHARGYVQPEGASELKDVTYYNPSAGSSAGDMISTADDLNKFFSYLLGGKLLKEQQLKQMLTTVPTGKEGIDGYGLGIYETKLPSGVSIWGHTGGILGFTTLVGGKLGGKHTLVVNWNSLGRTDSPNPFKQILLAEFSK
>NZ_CP040335.1|WP_157418284.1|1250_2021_-|hypothetical-protein
MYEEHLCFKLPEGRKKIWRYMDFTKFMDMLDKESIFFTRSDKFQDKFEGVYPKMNRELRPKNYKEELEKLPPEARENFFKSLDSIEIFAEFLKRFTLINCWHMNEYESAALWDLYLKSNEGIAIQSSVERLVKCFKGNKEKFYIGEVEYIDYKKTIIPEGNFFYPFTFKRKSFEHERELRVVHLLELPAVDDAIDYKAPSPLEFGMPIKCDIKELIERVYVSPTAPEWVFELVCSMCQKFNLDVEVIKSELSELPY
>NZ_CP040335.1|WP_157418283.1|722_872_-|hypothetical-protein
MKMPLTKHWCMDKRCGFEETSHKIRDGWKCPKCNGLMMYQIVKKDKRRG
>NZ_CP040335.1|WP_157418282.1|392_719_-|HNH-endonuclease
MQPLTIQEINKLYEQDNIIKFYKHPYWRKHIRILALERDNSECQECKRKGKYSKGRNVHHIKELRDRPDLAYTLSNLETLCIQCHNKEHCKEKNIVKKRCTIVDEERW
>NZ_CP040335.1|WP_098205548.1|10713_11169_+|hypothetical-protein
MNYQNDNNSKPCNCPSPTSNSLNVVQTTPSIVSVNSAIPLDTVVNSNGTAISFTPPTTVLLEGGRTYLAIYEVQVIIQPGGNSAGVTMYLNNNPIIGSGTSLGYTAGFTSVSAPAIFTTPPGIASTLTVNVGPYSNSLNTLGLTLAVVALT
>NZ_CP040335.1|WP_065228892.1|12076_12484_+|DUF4870-domain-containing-protein
MIPTQEKNIKLIMHFLTLLSFFILIFFSVTIFYIPLIFYFVYKSQNIQKNILEAMFYQLFIWIITVIWNLFIIRILMLSLSNLDLASNNALIIFGIAPLYLILFLLLIFGPIKGILYVLQEKDFHYPIISKWINK
>NZ_CP040335.1|WP_157418287.1|12716_13172_-|nucleotide-pyrophosphohydrolase
MKEMKNGVLEVTKLISKSKEGQALMNNNQICGLDQYQEAALRTWNTNQDFGGRVLNAALGLSVEAGEVADVVKKAIFHGHGFDPAHCPGEEEGNTHKIALELGDILYYISIMSHEMGYTLEDIAQMNISKLATRYPDGFSREASQNRVDMK
>NZ_CP040335.1|WP_000109490.1|13191_13443_-|hypothetical-protein
MSVARNHEAMKESRLKIYIALEEANFIWDERDVVRFREMWSQGMSLPKMAKALRRHQAEVALLVIDQADKYLIENRPIGLGIC
>NZ_CP040335.1|WP_000717829.1|13468_13636_-|DUF3954-domain-containing-protein
MKKIEIDVSSNKLYIVKDGNVTAVNPPISGFGEQVAVWVNGKVDRVDTKFTEKIK
>NZ_CP040335.1|WP_157418288.1|13654_14014_-|cell-division-protein-SepF
MSKQLNIFDVEPAICEFDVMKANVKKGNGRVTYADVRVQVPNNAKSTDELPRTTKQDDRYDIFEQYVMAIWRFQRAVDKFFNWDTAEELCKAARDKKEIIPVRIYLGSGFKPDVVEYMR
>NZ_CP040335.1|WP_157418289.1|14006_14285_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MKNTGIARKVDELGRVVIPVELRRTLGIVEGTALDFHVEGENIVLRKYEKSCFVTGEVSETNIELLGGRMFLSKEGAIELLDLIQKSGMAHV
>NZ_CP040335.1|WP_157418290.1|14288_15344_-|DnaD-domain-protein
MNNKVLQIGQINFRGNVIDHGWFKTLTLDNGKPNIVAITILGEIVYWYKPTEVRSEESSQVQYKQKFKADTLQKSYQQLADSFGFTKRQVKEACDFLKERGLIKIEFRTILVNGTRCNNVMYVEPVPEMIQKISIIYWRNGNPPTLKSNSPITLESKRVLHSKAIPSYDETEESLTLERKTNTEITTKITTNINDDDATSSQKLIDQEFKTSYNFLLEKGIPLSEIAIQELGEFCDRFGNELVIHAVNKAIDENVPKWRYIRSILSSWEKEKVKTLNDVATLDTRFEMSKKNNKRTGKGYSKRTEVVPDWLRKQEEQEPIQQPQQTQSDNLEDNKKRLDEILNKYKNTKGE
>NZ_CP040335.1|WP_000522030.1|15565_15832_-|helix-turn-helix-domain-containing-protein
MGLDQIIKESIREVVREEIQAALASFQQQSQPNKVMRVKEAAAYLNIAVCRMYELANHPHFPVIREGRKLLFLQKDLEAWLEAQKEVI
>NZ_CP040335.1|WP_000854271.1|15887_16079_-|helix-turn-helix-transcriptional-regulator
MKTLKQLRVEQGYTCREVAEAVGITEVYYWYIENGKRRPYYDLIVKIAEFFKVKLDAIKIFCP

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Crispr_ID: NZ_CP040335_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040335_2

9142-9209

Orphan

Consensus_repeat	Method
CAGGGGATTCAAGGTAATCCGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040335_2

>merge|NZ_CP040335|2|9142-9209|CRISPRCasFinder
CAAGGTATTCAAGGTATCCAAGGGATTCCTGGCCCCACTGGACCTCAAGGAAGTCAAGGGATTCAGGG

>NZ_CP040335|2|2|9142-9209|CRISPRCasFinder
CAAGGTATTCAAGGTATCCAAGG	GATTCCTGGCCCCACTGGACCT
CAAGGAAGTCAAGGGATTCAGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040335.1\|WP_053564381.1\|5503_6046_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271192
NZ_CP040335.1\|WP_001013578.1\|6826_7015_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040335.1\|WP_157418287.1\|12716_13172_-\|nucleotide-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|212148
NZ_CP040335.1\|WP_053564380.1\|4339_5290_-\|nucleoside-hydrolase	unknown	unknown	gnl\|CDD\|238257
NZ_CP040335.1\|WP_157418288.1\|13654_14014_-\|cell-division-protein-SepF	unknown	unknown	unknown
NZ_CP040335.1\|WP_157418285.1\|2358_3528_-\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NZ_CP040335.1\|WP_157418282.1\|392_719_-\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|366837
NZ_CP040335.1\|WP_000854271.1\|15887_16079_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP040335.1\|WP_157418283.1\|722_872_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182255
NZ_CP040335.1\|WP_000109490.1\|13191_13443_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040335.1\|WP_157418289.1\|14006_14285_-\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|131898
NZ_CP040335.1\|WP_098205548.1\|10713_11169_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040335.1\|WP_157418284.1\|1250_2021_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040335.1\|WP_000166175.1\|6045_6528_-\|ArpU-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|273725
NZ_CP040335.1\|WP_000522030.1\|15565_15832_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378935
NZ_CP040335.1\|WP_000717829.1\|13468_13636_-\|DUF3954-domain-containing-protein	unknown	unknown	gnl\|CDD\|315731
NZ_CP040335.1\|WP_000130745.1\|7035_7158_-\|DUF3983-domain-containing-protein	unknown	unknown	gnl\|CDD\|289882
NZ_CP040335.1\|WP_065228892.1\|12076_12484_+\|DUF4870-domain-containing-protein	unknown	unknown	unknown
NZ_CP040335.1\|WP_157418290.1\|14288_15344_-\|DnaD-domain-protein	unknown	unknown	gnl\|CDD\|273630
NZ_CP040335.1\|WP_098683955.1\|7187_7370_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP040335.1\|WP_053564381.1\|5503_6046_-\|site-specific-integrase	gnl\|CDD\|271192	cd01192, INT_C_like_3, Uncharacterized site-specific tyrosine recombinase, C-terminal catalytic domain. Tyrosine recombinase (integrase) belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain contains six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	6.77036e-66
NZ_CP040335.1\|WP_157418287.1\|12716_13172_-\|nucleotide-pyrophosphohydrolase	gnl\|CDD\|212148	cd11541, NTP-PPase_u4, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea. This family corresponds to a group of uncharacterized hypothetical proteins from bacteria, showing a high sequence similarity to the dimeric 2-deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTP pyrophosphatase or dUTPase) and NTP-PPase MazG proteins. However, unlike typical tandem-domain MazG proteins, members in this family consist of a single MazG-like domain that contains a well conserved divalent ion-binding motif EXX[E/D].	2.4166e-32
NZ_CP040335.1\|WP_053564380.1\|4339_5290_-\|nucleoside-hydrolase	gnl\|CDD\|238257	cd00455, nuc_hydro, nuc_hydro: Nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes vary in their substrate specificity. This group contains eukaryotic, bacterial and archeal proteins similar to the inosine-uridine preferring nucleoside hydrolase from Crithidia fasciculata, the xanthosine-inosine-uridine-adenosine-preferring nucleoside hydrolase RihC from Salmonella enterica serovar Typhimurium, the purine-specific inosine-adenosine-guanosine-preferring nucleoside hydrolase from Trypanosoma vivax and, pyrimidine-specific uridine-cytidine preferring nucleoside hydrolases such as URH1 from Saccharomyces cerevisiae, RihA and RihB from Escherichia coli. Nucleoside hydrolases are of interest as a target for antiprotozoan drugs as, no nucleoside hydrolase activity or genes encoding these enzymes have been detected in humans and, parasitic protozoans lack de novo purine synthesis relying on nucleoside hydrolase to scavenge purine and/or pyrimidines from the environment. .	1.9181e-116
NZ_CP040335.1\|WP_157418285.1\|2358_3528_-\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	8.93307e-72
NZ_CP040335.1\|WP_157418282.1\|392_719_-\|HNH-endonuclease	gnl\|CDD\|366837	pfam01844, HNH, HNH endonuclease. His-Asn-His (HNH) proteins are a very common family of small nucleic acid-binding proteins that are generally associated with endonuclease activity.	9.46754e-08
NZ_CP040335.1\|WP_157418283.1\|722_872_-\|hypothetical-protein	gnl\|CDD\|182255	PRK10125, PRK10125, colanic acid biosynthesis glycosyltransferase WcaC.	9.27195e-05
NZ_CP040335.1\|WP_000854271.1\|15887_16079_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.16346e-12
NZ_CP040335.1\|WP_157418289.1\|14006_14285_-\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl\|CDD\|131898	TIGR02851, stage_V_sporulation_protein_T, stage V sporulation protein T. Members of this protein family are the stage V sporulation protein T (SpoVT), a protein of the sporulation/germination program in Bacillus subtilis and related species. The amino-terminal 50 amino acids are nearly perfectly conserved across all endospore-forming bacteria. SpoVT is a DNA-binding transcriptional regulator related to AbrB (See pfam04014). [Regulatory functions, DNA interactions, Cellular processes, Sporulation and germination].	7.68309e-11
NZ_CP040335.1\|WP_157418290.1\|14288_15344_-\|DnaD-domain-protein	gnl\|CDD\|273630	TIGR01446, replication_protein, DnaD and phage-associated domain. This model represents the conserved domain of DnaD, part of Bacillus subtilis replication restart primosome, and of a number of phage-associated proteins. Members, both chromosomal or phage-associated, are found in the Bacillus/Clostridium group of Gram-positive bacteria. [DNA metabolism, DNA replication, recombination, and repair, Mobile and extrachromosomal element functions, Prophage functions].	3.19097e-11
NZ_CP040335.1\|WP_000166175.1\|6045_6528_-\|ArpU-family-transcriptional-regulator	gnl\|CDD\|273725	TIGR01637, Putative_autolysin_regulatory_protein_ArpU, phage transcriptional regulator, ArpU family. This model represents a family of phage proteins, including ArpU, called a putative autolysin regulatory protein. ArpU was described as a regulator of cellular muramidase-2 of Enterococcus hirae but appears to have been cloned from a prophage. This family appears related to the RinA family of bacteriophage transcriptional activators and to some sporulation-specific sigma factors. We propose that this is a phage transcriptional activator family. [Mobile and extrachromosomal element functions, Prophage functions, Regulatory functions, DNA interactions].	3.05821e-16
NZ_CP040335.1\|WP_000522030.1\|15565_15832_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	1.86891e-08
NZ_CP040335.1\|WP_000717829.1\|13468_13636_-\|DUF3954-domain-containing-protein	gnl\|CDD\|315731	pfam13128, DUF3954, Protein of unknown function (DUF3954). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and viruses. Proteins in this family are approximately 60 amino acids in length.	3.77667e-15
NZ_CP040335.1\|WP_000130745.1\|7035_7158_-\|DUF3983-domain-containing-protein	gnl\|CDD\|289882	pfam13137, DUF3983, Protein of unknown function (DUF3983). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and viruses. Proteins in this family are approximately 40 amino acids in length. There is a conserved AWRN sequence motif.	1.50628e-05

>NZ_CP040335.1|WP_098683955.1|7187_7370_-|hypothetical-protein
MEGKTEPKMVPMASYGSNKEKQCVEFQLLINEEIYVMPVHERDVKGMETWFLLKKHNLIK
>NZ_CP040335.1|WP_000130745.1|7035_7158_-|DUF3983-domain-containing-protein
MTDLKKRKIRKAIARRTKAVEKYQVDNAWRNIFVKAGIIK
>NZ_CP040335.1|WP_001013578.1|6826_7015_-|hypothetical-protein
MNGKQFFGMYWALYLIIMFVTFSNAKSFIQAGIILVLVILISEVDHKYGFYKGSKKAKSNQI
>NZ_CP040335.1|WP_000166175.1|6045_6528_-|ArpU-family-transcriptional-regulator
MTKQLSFLPKIDRTATQEELEGVLESVRIHRQFGMMRKEMKVTPSYEIREHGPTHAVGKPLEDVAIANIQQSKREEWLEKMSLSIDQFLNRLGNGRAGSIQRDIIYKRYLEEEDVCDYMVYNEIGMSERTYRRWKSKAFYKLAFALGLEVYETEETGGNK
>NZ_CP040335.1|WP_053564381.1|5503_6046_-|site-specific-integrase
MNFVQPIRDSEQIQQIKEYLKEKNERNYILFVIGINTGLRISDILKLKVGDLNGSHISMREMKTGKQKRIHITAALRRELKWYIEDMEDYEYIIKSRQGKNRPIGRSMAYKILSTTAAKFGLEEIGTHTLRKTFGYHMYMQTKNIALLMEIFNHSSERVTLRYIGVNQDAMDKAMTRFKI
>NZ_CP040335.1|WP_053564380.1|4339_5290_-|nucleoside-hydrolase
MQKKVLLFTDLGIDDAFAILYTFFRKDIQLVGIVADYGNVSRENVIRNINYLKYIAGREEIPVFLGASVPLTGILIQYFPEVHGKVGLGPIIPPEISYPVYPLNDIYQIIESNLEDLTIINLGRLSSLATTFVLNLETMRNVRECICMGGAFFYPGNVTAVAEANFHADPYAANLILQHAKNLTIIPLNVTQHAIVTTEMVEQIDAFHRNTQDLAGLIIKPMLDYYYNFYSKSNPGISGSPMHDFVTVWYLLNREAVSLSRVPIKVIPDQGEGFGQSIADFRFVTNPGYKTHNVAFQFDYERFRKDIMETFLKKRV
>NZ_CP040335.1|WP_157418285.1|2358_3528_-|serine-hydrolase
MKIRSQITCASLALLIAGSSLLYTTPTSIVKAEPTQNVSSSLQTNTQRDRTSVKQAMRDTLQFGYPGILAKTSEGGKTWGYAAGIADLRTKKPMKTDFRFRIGSVTKTFTATVVLQLVGENRLKLDDHIEDWLPGVIQGNGYDGNKITIREILNHTSGIAEYSRSKDVDFTDTKKSYTAEELVKMGISLPPDFAPGKGWSYSNTGYVLLGILIEKVTGNSYAEEVENRIIEPLELSNTFLPGNSSVIPGTNHARGYVQPEGASELKDVTYYNPSAGSSAGDMISTADDLNKFFSYLLGGKLLKEQQLKQMLTTVPTGKEGIDGYGLGIYETKLPSGVSIWGHTGGILGFTTLVGGKLGGKHTLVVNWNSLGRTDSPNPFKQILLAEFSK
>NZ_CP040335.1|WP_157418284.1|1250_2021_-|hypothetical-protein
MYEEHLCFKLPEGRKKIWRYMDFTKFMDMLDKESIFFTRSDKFQDKFEGVYPKMNRELRPKNYKEELEKLPPEARENFFKSLDSIEIFAEFLKRFTLINCWHMNEYESAALWDLYLKSNEGIAIQSSVERLVKCFKGNKEKFYIGEVEYIDYKKTIIPEGNFFYPFTFKRKSFEHERELRVVHLLELPAVDDAIDYKAPSPLEFGMPIKCDIKELIERVYVSPTAPEWVFELVCSMCQKFNLDVEVIKSELSELPY
>NZ_CP040335.1|WP_157418283.1|722_872_-|hypothetical-protein
MKMPLTKHWCMDKRCGFEETSHKIRDGWKCPKCNGLMMYQIVKKDKRRG
>NZ_CP040335.1|WP_157418282.1|392_719_-|HNH-endonuclease
MQPLTIQEINKLYEQDNIIKFYKHPYWRKHIRILALERDNSECQECKRKGKYSKGRNVHHIKELRDRPDLAYTLSNLETLCIQCHNKEHCKEKNIVKKRCTIVDEERW
>NZ_CP040335.1|WP_098205548.1|10713_11169_+|hypothetical-protein
MNYQNDNNSKPCNCPSPTSNSLNVVQTTPSIVSVNSAIPLDTVVNSNGTAISFTPPTTVLLEGGRTYLAIYEVQVIIQPGGNSAGVTMYLNNNPIIGSGTSLGYTAGFTSVSAPAIFTTPPGIASTLTVNVGPYSNSLNTLGLTLAVVALT
>NZ_CP040335.1|WP_065228892.1|12076_12484_+|DUF4870-domain-containing-protein
MIPTQEKNIKLIMHFLTLLSFFILIFFSVTIFYIPLIFYFVYKSQNIQKNILEAMFYQLFIWIITVIWNLFIIRILMLSLSNLDLASNNALIIFGIAPLYLILFLLLIFGPIKGILYVLQEKDFHYPIISKWINK
>NZ_CP040335.1|WP_157418287.1|12716_13172_-|nucleotide-pyrophosphohydrolase
MKEMKNGVLEVTKLISKSKEGQALMNNNQICGLDQYQEAALRTWNTNQDFGGRVLNAALGLSVEAGEVADVVKKAIFHGHGFDPAHCPGEEEGNTHKIALELGDILYYISIMSHEMGYTLEDIAQMNISKLATRYPDGFSREASQNRVDMK
>NZ_CP040335.1|WP_000109490.1|13191_13443_-|hypothetical-protein
MSVARNHEAMKESRLKIYIALEEANFIWDERDVVRFREMWSQGMSLPKMAKALRRHQAEVALLVIDQADKYLIENRPIGLGIC
>NZ_CP040335.1|WP_000717829.1|13468_13636_-|DUF3954-domain-containing-protein
MKKIEIDVSSNKLYIVKDGNVTAVNPPISGFGEQVAVWVNGKVDRVDTKFTEKIK
>NZ_CP040335.1|WP_157418288.1|13654_14014_-|cell-division-protein-SepF
MSKQLNIFDVEPAICEFDVMKANVKKGNGRVTYADVRVQVPNNAKSTDELPRTTKQDDRYDIFEQYVMAIWRFQRAVDKFFNWDTAEELCKAARDKKEIIPVRIYLGSGFKPDVVEYMR
>NZ_CP040335.1|WP_157418289.1|14006_14285_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MKNTGIARKVDELGRVVIPVELRRTLGIVEGTALDFHVEGENIVLRKYEKSCFVTGEVSETNIELLGGRMFLSKEGAIELLDLIQKSGMAHV
>NZ_CP040335.1|WP_157418290.1|14288_15344_-|DnaD-domain-protein
MNNKVLQIGQINFRGNVIDHGWFKTLTLDNGKPNIVAITILGEIVYWYKPTEVRSEESSQVQYKQKFKADTLQKSYQQLADSFGFTKRQVKEACDFLKERGLIKIEFRTILVNGTRCNNVMYVEPVPEMIQKISIIYWRNGNPPTLKSNSPITLESKRVLHSKAIPSYDETEESLTLERKTNTEITTKITTNINDDDATSSQKLIDQEFKTSYNFLLEKGIPLSEIAIQELGEFCDRFGNELVIHAVNKAIDENVPKWRYIRSILSSWEKEKVKTLNDVATLDTRFEMSKKNNKRTGKGYSKRTEVVPDWLRKQEEQEPIQQPQQTQSDNLEDNKKRLDEILNKYKNTKGE
>NZ_CP040335.1|WP_000522030.1|15565_15832_-|helix-turn-helix-domain-containing-protein
MGLDQIIKESIREVVREEIQAALASFQQQSQPNKVMRVKEAAAYLNIAVCRMYELANHPHFPVIREGRKLLFLQKDLEAWLEAQKEVI
>NZ_CP040335.1|WP_000854271.1|15887_16079_-|helix-turn-helix-transcriptional-regulator
MKTLKQLRVEQGYTCREVAEAVGITEVYYWYIENGKRRPYYDLIVKIAEFFKVKLDAIKIFCP

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP040335_1	1.1\|8727\|31\|NZ_CP040335\|CRISPRCasFinder	8727-8757	31	NZ_CP040335	Bacillus cereus strain DLOU-Changhai plasmid unnamed1, complete sequence	8727-8757	0	1.0
NZ_CP040335_1	1.2\|8781\|31\|NZ_CP040335\|CRISPRCasFinder	8781-8811	31	NZ_CP040335	Bacillus cereus strain DLOU-Changhai plasmid unnamed1, complete sequence	8781-8811	0	1.0
NZ_CP040335_1	1.3\|8835\|49\|NZ_CP040335\|CRISPRCasFinder	8835-8883	49	NZ_CP040335	Bacillus cereus strain DLOU-Changhai plasmid unnamed1, complete sequence	8835-8883	0	1.0
NZ_CP040335_1	1.4\|8907\|22\|NZ_CP040335\|CRISPRCasFinder	8907-8928	22	NZ_CP040335	Bacillus cereus strain DLOU-Changhai plasmid unnamed1, complete sequence	8907-8928	0	1.0
NZ_CP040335_2	2.1\|9165\|22\|NZ_CP040335\|CRISPRCasFinder	9165-9186	22	NZ_CP040335	Bacillus cereus strain DLOU-Changhai plasmid unnamed1, complete sequence	9165-9186	0	1.0
NZ_CP040335_1	1.4\|8907\|22\|NZ_CP040335\|CRISPRCasFinder	8907-8928	22	NZ_CP040335	Bacillus cereus strain DLOU-Changhai plasmid unnamed1, complete sequence	8916-8937	1	0.955
NZ_CP040335_1	1.4\|8907\|22\|NZ_CP040335\|CRISPRCasFinder	8907-8928	22	NZ_CP040335	Bacillus cereus strain DLOU-Changhai plasmid unnamed1, complete sequence	8925-8946	1	0.955
NZ_CP040335_1	1.2\|8781\|31\|NZ_CP040335\|CRISPRCasFinder	8781-8811	31	NZ_CP040335	Bacillus cereus strain DLOU-Changhai plasmid unnamed1, complete sequence	8988-9018	5	0.839
NZ_CP040335_1	1.1\|8727\|31\|NZ_CP040335\|CRISPRCasFinder	8727-8757	31	NZ_CP044980	Bacillus thuringiensis strain BT62 plasmid pBT62B, complete sequence	4012-4042	6	0.806
NZ_CP040335_1	1.1\|8727\|31\|NZ_CP040335\|CRISPRCasFinder	8727-8757	31	NZ_CP044980	Bacillus thuringiensis strain BT62 plasmid pBT62B, complete sequence	3902-3932	7	0.774
NZ_CP040335_1	1.1\|8727\|31\|NZ_CP040335\|CRISPRCasFinder	8727-8757	31	NZ_CP044980	Bacillus thuringiensis strain BT62 plasmid pBT62B, complete sequence	3794-3824	8	0.742
NZ_CP040335_1	1.1\|8727\|31\|NZ_CP040335\|CRISPRCasFinder	8727-8757	31	NZ_CP044980	Bacillus thuringiensis strain BT62 plasmid pBT62B, complete sequence	3848-3878	8	0.742
NZ_CP040335_1	1.1\|8727\|31\|NZ_CP040335\|CRISPRCasFinder	8727-8757	31	NZ_CP044980	Bacillus thuringiensis strain BT62 plasmid pBT62B, complete sequence	3957-3987	8	0.742
NZ_CP040335_1	1.2\|8781\|31\|NZ_CP040335\|CRISPRCasFinder	8781-8811	31	KC294142	Pseudomonas phage PaP4	6887-6917	8	0.742
NZ_CP040335_1	1.2\|8781\|31\|NZ_CP040335\|CRISPRCasFinder	8781-8811	31	NC_042343	Pseudomonas phage PaP4, complete genome	6887-6917	8	0.742
NZ_CP040335_1	1.2\|8781\|31\|NZ_CP040335\|CRISPRCasFinder	8781-8811	31	MT119371	Pseudomonas phage oldone, complete genome	7617-7647	8	0.742
NZ_CP040335_1	1.2\|8781\|31\|NZ_CP040335\|CRISPRCasFinder	8781-8811	31	MG589385	Pseudomonas phage phiPA01_302, complete genome	7618-7648	8	0.742
NZ_CP040335_1	1.1\|8727\|31\|NZ_CP040335\|CRISPRCasFinder	8727-8757	31	NZ_CP042479	Citrobacter freundii strain C50 plasmid pC50_001, complete sequence	108070-108100	9	0.71
NZ_CP040335_1	1.1\|8727\|31\|NZ_CP040335\|CRISPRCasFinder	8727-8757	31	CP049311	Salmonella enterica subsp. enterica serovar Heidelberg strain CVM N53023 plasmid pN53023, complete sequence	100769-100799	9	0.71
NZ_CP040335_1	1.1\|8727\|31\|NZ_CP040335\|CRISPRCasFinder	8727-8757	31	NZ_CP026208	Escherichia coli strain ECONIH5 plasmid pECO-109b, complete sequence	187403-187433	9	0.71
NZ_CP040335_1	1.1\|8727\|31\|NZ_CP040335\|CRISPRCasFinder	8727-8757	31	NZ_CP010360	Enterobacter roggenkampii strain 35734 plasmid p35734-141.404kb, complete sequence	58874-58904	9	0.71
NZ_CP040335_1	1.1\|8727\|31\|NZ_CP040335\|CRISPRCasFinder	8727-8757	31	CP049307	Salmonella enterica subsp. enterica serovar Heidelberg strain CVM N58631 plasmid p58631, complete sequence	289799-289829	9	0.71
NZ_CP040335_1	1.1\|8727\|31\|NZ_CP040335\|CRISPRCasFinder	8727-8757	31	NZ_KY494864	Pseudomonas aeruginosa strain FFUP_PS_37 plasmid pJB37, complete sequence	411118-411148	9	0.71
NZ_CP040335_1	1.1\|8727\|31\|NZ_CP040335\|CRISPRCasFinder	8727-8757	31	NZ_KT935446	Klebsiella pneumoniae strain Kp2964 plasmid 2964TF, complete sequence	45341-45371	9	0.71
NZ_CP040335_1	1.1\|8727\|31\|NZ_CP040335\|CRISPRCasFinder	8727-8757	31	NZ_CP010380	Enterobacter hormaechei subsp. hormaechei strain 34983 plasmid p34983-328.905kb, complete sequence	294872-294902	9	0.71
NZ_CP040335_1	1.1\|8727\|31\|NZ_CP040335\|CRISPRCasFinder	8727-8757	31	NZ_CP012168	Enterobacter hormaechei subsp. steigerwaltii strain 34998 plasmid p34998-239.973kb, complete sequence	42968-42998	9	0.71
NZ_CP040335_1	1.1\|8727\|31\|NZ_CP040335\|CRISPRCasFinder	8727-8757	31	NZ_CP032179	Citrobacter freundii strain AR_0116 plasmid unnamed1, complete sequence	188496-188526	9	0.71
NZ_CP040335_1	1.1\|8727\|31\|NZ_CP040335\|CRISPRCasFinder	8727-8757	31	NZ_CP017294	Pseudomonas aeruginosa strain PA83 plasmid unnamed1, complete sequence	191784-191814	9	0.71
NZ_CP040335_1	1.1\|8727\|31\|NZ_CP040335\|CRISPRCasFinder	8727-8757	31	NZ_CP031135	Escherichia coli strain CFSAN064035 plasmid pGMI17-003_1, complete sequence	221911-221941	9	0.71
NZ_CP040335_1	1.2\|8781\|31\|NZ_CP040335\|CRISPRCasFinder	8781-8811	31	AP013580	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C16-MedDCM-OCT-S43-C44, * SEQUENCING IN PROGRESS *	11062-11092	9	0.71

1. spacer 1.1|8727|31|NZ_CP040335|CRISPRCasFinder matches to NZ_CP040335 (Bacillus cereus strain DLOU-Changhai plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

acctactgggcctcaaggtatttctggacct	CRISPR spacer
acctactgggcctcaaggtatttctggacct	Protospacer
*******************************

2. spacer 1.2|8781|31|NZ_CP040335|CRISPRCasFinder matches to NZ_CP040335 (Bacillus cereus strain DLOU-Changhai plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

atctattggtccaactggaccttctggaatt	CRISPR spacer
atctattggtccaactggaccttctggaatt	Protospacer
*******************************

3. spacer 1.3|8835|49|NZ_CP040335|CRISPRCasFinder matches to NZ_CP040335 (Bacillus cereus strain DLOU-Changhai plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

cattcctggcattcaaggtcctattggacccactggaataacagggggc	CRISPR spacer
cattcctggcattcaaggtcctattggacccactggaataacagggggc	Protospacer
*************************************************

4. spacer 1.4|8907|22|NZ_CP040335|CRISPRCasFinder matches to NZ_CP040335 (Bacillus cereus strain DLOU-Changhai plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

cattcaagggattcaagggatt	CRISPR spacer
cattcaagggattcaagggatt	Protospacer
**********************

5. spacer 2.1|9165|22|NZ_CP040335|CRISPRCasFinder matches to NZ_CP040335 (Bacillus cereus strain DLOU-Changhai plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gattcctggccccactggacct	CRISPR spacer
gattcctggccccactggacct	Protospacer
**********************

6. spacer 1.4|8907|22|NZ_CP040335|CRISPRCasFinder matches to NZ_CP040335 (Bacillus cereus strain DLOU-Changhai plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.955

cattcaagggattcaagggatt	CRISPR spacer
gattcaagggattcaagggatt	Protospacer
 *********************

7. spacer 1.4|8907|22|NZ_CP040335|CRISPRCasFinder matches to NZ_CP040335 (Bacillus cereus strain DLOU-Changhai plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.955

cattcaagggattcaagggatt	CRISPR spacer
gattcaagggattcaagggatt	Protospacer
 *********************

8. spacer 1.2|8781|31|NZ_CP040335|CRISPRCasFinder matches to NZ_CP040335 (Bacillus cereus strain DLOU-Changhai plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.839

atctattggtccaactggaccttctggaatt	CRISPR spacer
ttctgtaggtccaactggaccttctggagct	Protospacer
 ***.* *********************..*

9. spacer 1.1|8727|31|NZ_CP040335|CRISPRCasFinder matches to NZ_CP044980 (Bacillus thuringiensis strain BT62 plasmid pBT62B, complete sequence) position: , mismatch: 6, identity: 0.806

acctactgggcctcaaggtatttctggacct	CRISPR spacer
acctactgggccacaaggtattcagggaatt	Protospacer
************ *********.  *** .*

10. spacer 1.1|8727|31|NZ_CP040335|CRISPRCasFinder matches to NZ_CP044980 (Bacillus thuringiensis strain BT62 plasmid pBT62B, complete sequence) position: , mismatch: 7, identity: 0.774

acctactgggcctcaaggtatttctggacct	CRISPR spacer
acctactgggccacaaggtattcaggggaat	Protospacer
************ *********.  **.  *

11. spacer 1.1|8727|31|NZ_CP040335|CRISPRCasFinder matches to NZ_CP044980 (Bacillus thuringiensis strain BT62 plasmid pBT62B, complete sequence) position: , mismatch: 8, identity: 0.742

acctactgggcctcaaggtatttctggacct	CRISPR spacer
acctactgggccacaaggtattcaagggatc	Protospacer
************ *********.  **. ..

12. spacer 1.1|8727|31|NZ_CP040335|CRISPRCasFinder matches to NZ_CP044980 (Bacillus thuringiensis strain BT62 plasmid pBT62B, complete sequence) position: , mismatch: 8, identity: 0.742

acctactgggcctcaaggtatttctggacct	CRISPR spacer
acctactgggccacaaggtattcaagggatc	Protospacer
************ *********.  **. ..

13. spacer 1.1|8727|31|NZ_CP040335|CRISPRCasFinder matches to NZ_CP044980 (Bacillus thuringiensis strain BT62 plasmid pBT62B, complete sequence) position: , mismatch: 8, identity: 0.742

acctactgggcctcaaggtatttctggacct	CRISPR spacer
acctactgggccacaaggtattcaagggatc	Protospacer
************ *********.  **. ..

14. spacer 1.2|8781|31|NZ_CP040335|CRISPRCasFinder matches to KC294142 (Pseudomonas phage PaP4) position: , mismatch: 8, identity: 0.742

atctattggtccaactggaccttctggaatt	CRISPR spacer
tccaccttgtccaactggatcttcaggaatt	Protospacer
 .*  .* ***********.**** ******

15. spacer 1.2|8781|31|NZ_CP040335|CRISPRCasFinder matches to NC_042343 (Pseudomonas phage PaP4, complete genome) position: , mismatch: 8, identity: 0.742

atctattggtccaactggaccttctggaatt	CRISPR spacer
tccaccttgtccaactggatcttcaggaatt	Protospacer
 .*  .* ***********.**** ******

16. spacer 1.2|8781|31|NZ_CP040335|CRISPRCasFinder matches to MT119371 (Pseudomonas phage oldone, complete genome) position: , mismatch: 8, identity: 0.742

atctattggtccaactggaccttctggaatt	CRISPR spacer
tccaccttgtccaactgaaccttcaggaatt	Protospacer
 .*  .* *********.****** ******

17. spacer 1.2|8781|31|NZ_CP040335|CRISPRCasFinder matches to MG589385 (Pseudomonas phage phiPA01_302, complete genome) position: , mismatch: 8, identity: 0.742

atctattggtccaactggaccttctggaatt	CRISPR spacer
tccaccttgtccaactggatcttcaggaatt	Protospacer
 .*  .* ***********.**** ******

18. spacer 1.1|8727|31|NZ_CP040335|CRISPRCasFinder matches to NZ_CP042479 (Citrobacter freundii strain C50 plasmid pC50_001, complete sequence) position: , mismatch: 9, identity: 0.71

acctactgggcctcaaggtatttctggacct	CRISPR spacer
atgcactgggcctcacggtgtttctggtaac	Protospacer
*. .*********** ***.*******   .

19. spacer 1.1|8727|31|NZ_CP040335|CRISPRCasFinder matches to CP049311 (Salmonella enterica subsp. enterica serovar Heidelberg strain CVM N53023 plasmid pN53023, complete sequence) position: , mismatch: 9, identity: 0.71

acctactgggcctcaaggtatttctggacct	CRISPR spacer
atgcactgggcctcacggtgtttctggtaac	Protospacer
*. .*********** ***.*******   .

20. spacer 1.1|8727|31|NZ_CP040335|CRISPRCasFinder matches to NZ_CP026208 (Escherichia coli strain ECONIH5 plasmid pECO-109b, complete sequence) position: , mismatch: 9, identity: 0.71

acctactgggcctcaaggtatttctggacct	CRISPR spacer
atgcactgggcctcacggtgtttctggtaac	Protospacer
*. .*********** ***.*******   .

21. spacer 1.1|8727|31|NZ_CP040335|CRISPRCasFinder matches to NZ_CP010360 (Enterobacter roggenkampii strain 35734 plasmid p35734-141.404kb, complete sequence) position: , mismatch: 9, identity: 0.71

acctactgggcctcaaggtatttctggacct	CRISPR spacer
atgcactgggcctcacggtgtttctggtaac	Protospacer
*. .*********** ***.*******   .

22. spacer 1.1|8727|31|NZ_CP040335|CRISPRCasFinder matches to CP049307 (Salmonella enterica subsp. enterica serovar Heidelberg strain CVM N58631 plasmid p58631, complete sequence) position: , mismatch: 9, identity: 0.71

acctactgggcctcaaggtatttctggacct	CRISPR spacer
atgcactgggcctcacggtgtttctggtaac	Protospacer
*. .*********** ***.*******   .

23. spacer 1.1|8727|31|NZ_CP040335|CRISPRCasFinder matches to NZ_KY494864 (Pseudomonas aeruginosa strain FFUP_PS_37 plasmid pJB37, complete sequence) position: , mismatch: 9, identity: 0.71

acctactgggcctcaaggtatttctggacct	CRISPR spacer
atgcactgggcctcacggtgtttctggtaac	Protospacer
*. .*********** ***.*******   .

24. spacer 1.1|8727|31|NZ_CP040335|CRISPRCasFinder matches to NZ_KT935446 (Klebsiella pneumoniae strain Kp2964 plasmid 2964TF, complete sequence) position: , mismatch: 9, identity: 0.71

acctactgggcctcaaggtatttctggacct	CRISPR spacer
atgcactgggcctcacggtgtttctggtaac	Protospacer
*. .*********** ***.*******   .

25. spacer 1.1|8727|31|NZ_CP040335|CRISPRCasFinder matches to NZ_CP010380 (Enterobacter hormaechei subsp. hormaechei strain 34983 plasmid p34983-328.905kb, complete sequence) position: , mismatch: 9, identity: 0.71

acctactgggcctcaaggtatttctggacct	CRISPR spacer
atgcactgggcctcacggtgtttctggtaac	Protospacer
*. .*********** ***.*******   .

26. spacer 1.1|8727|31|NZ_CP040335|CRISPRCasFinder matches to NZ_CP012168 (Enterobacter hormaechei subsp. steigerwaltii strain 34998 plasmid p34998-239.973kb, complete sequence) position: , mismatch: 9, identity: 0.71

acctactgggcctcaaggtatttctggacct	CRISPR spacer
atgcactgggcctcacggtgtttctggtaac	Protospacer
*. .*********** ***.*******   .

27. spacer 1.1|8727|31|NZ_CP040335|CRISPRCasFinder matches to NZ_CP032179 (Citrobacter freundii strain AR_0116 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.71

acctactgggcctcaaggtatttctggacct	CRISPR spacer
atgcactgggcctcacggtgtttctggtaac	Protospacer
*. .*********** ***.*******   .

28. spacer 1.1|8727|31|NZ_CP040335|CRISPRCasFinder matches to NZ_CP017294 (Pseudomonas aeruginosa strain PA83 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.71

acctactgggcctcaaggtatttctggacct	CRISPR spacer
atgcactgggcctcacggtgtttctggtaac	Protospacer
*. .*********** ***.*******   .

29. spacer 1.1|8727|31|NZ_CP040335|CRISPRCasFinder matches to NZ_CP031135 (Escherichia coli strain CFSAN064035 plasmid pGMI17-003_1, complete sequence) position: , mismatch: 9, identity: 0.71

acctactgggcctcaaggtatttctggacct	CRISPR spacer
atgcactgggcctcacggtgtttctggtaac	Protospacer
*. .*********** ***.*******   .

30. spacer 1.2|8781|31|NZ_CP040335|CRISPRCasFinder matches to AP013580 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C16-MedDCM-OCT-S43-C44, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.71

atctattggtccaactggaccttctggaatt	CRISPR spacer
ttctattggaccaactggaacttcaacacca	Protospacer
 ******** ********* **** . * .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

8550 : 19946

Bacillus_phage(83.33%)

integrase

attL 14706:14720|attR 20989:21003

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157418286.1\|8550_9858_+	collagen-like protein	A0A285PWR0	Cedratvirus	2.6e-38	62.6
WP_098205548.1\|10713_11169_+	hypothetical protein	NA	NA	NA	NA
WP_065228892.1\|12076_12484_+	DUF4870 domain-containing protein	NA	NA	NA	NA
WP_157418287.1\|12716_13172_-	nucleotide pyrophosphohydrolase	A0A0U4IBD0	Bacillus_phage	4.2e-20	47.4
WP_000109490.1\|13191_13443_-	hypothetical protein	A0A1B1P7W1	Bacillus_phage	3.4e-16	50.0
WP_000717829.1\|13468_13636_-	DUF3954 domain-containing protein	A0A1B0T6B8	Bacillus_phage	9.5e-15	64.2
WP_157418288.1\|13654_14014_-	cell division protein SepF	A0A1B1P7A1	Bacillus_phage	2.9e-32	54.2
WP_157418289.1\|14006_14285_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A2I7SC16	Paenibacillus_phage	7.9e-14	64.4
WP_157418290.1\|14288_15344_-	DnaD domain protein	H0USU2	Bacillus_phage	6.2e-59	43.5
14706:14720	attL	NA	NA	NA	NA
WP_000522030.1\|15565_15832_-	helix-turn-helix domain-containing protein	A0A0U3ULL9	Bacillus_phage	2.9e-37	94.1
WP_000854271.1\|15887_16079_-	helix-turn-helix transcriptional regulator	A0A0U3SLC2	Bacillus_phage	8.3e-23	85.2
WP_000491236.1\|16279_16633_+	helix-turn-helix transcriptional regulator	A0A0U3SD25	Bacillus_phage	2.1e-48	86.2
WP_033695148.1\|16670_16868_-	hypothetical protein	NA	NA	NA	NA
WP_000720921.1\|16954_17101_-	hypothetical protein	NA	NA	NA	NA
WP_025709561.1\|17138_18290_-	hypothetical protein	A0A0S2MVK2	Bacillus_phage	1.9e-53	34.4
WP_157418291.1\|18836_19946_+\|integrase	tyrosine-type recombinase/integrase	A0A0U3U8Y8	Bacillus_phage	3.7e-147	79.1
20989:21003	attR	NA	NA	NA	NA

DBSCAN-SWA_2

24517 : 39583

Bacillus_phage(58.33%)

terminase,protease,tail,capsid,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157418295.1\|24517_27247_-	endopeptidase	A0A1B1P770	Bacillus_phage	2.8e-236	50.2
WP_000227695.1\|27243_27930_-	hypothetical protein	A0A2H4J851	uncultured_Caudovirales_phage	2.4e-80	63.7
WP_157418296.1\|27922_31771_-\|tail	phage tail tape measure protein	B4XYQ3	Lactobacillus_phage	6.6e-50	29.7
WP_000159510.1\|31953_32304_-	hypothetical protein	A0A1S7FZ84	Listeria_phage	1.5e-09	36.5
WP_001145608.1\|32365_32935_-	hypothetical protein	A0A1B1P778	Bacillus_phage	2.7e-40	45.0
WP_001111193.1\|32936_33347_-	hypothetical protein	Q8W600	Listeria_phage	7.1e-11	33.1
WP_157418297.1\|33336_33717_-	hypothetical protein	NA	NA	NA	NA
WP_000963758.1\|33703_34060_-	hypothetical protein	NA	NA	NA	NA
WP_001282872.1\|34049_34373_-	hypothetical protein	A0A1B1P751	Bacillus_phage	5.4e-14	41.9
WP_000588590.1\|34386_35511_-\|capsid	phage major capsid protein	A0A1B1P752	Bacillus_phage	7.2e-98	50.0
WP_157418300.1\|35524_36157_-\|protease	Clp protease ClpP	D2XR17	Bacillus_phage	1.4e-34	45.5
WP_000512881.1\|36173_37418_-\|portal	phage portal protein	A0A1B1P754	Bacillus_phage	5.2e-73	37.5
WP_157418298.1\|37434_39111_-\|terminase	terminase large subunit	A0A1B1P766	Bacillus_phage	1.7e-180	57.8
WP_157418299.1\|39085_39583_-	RNA polymerase subunit sigma-70	E2ELI1	Clostridium_phage	3.7e-22	43.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP040334

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP040334_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040334_1

1215012-1215145

Orphan

Consensus_repeat	Method
GACAAATCTCAAAAAGAAGAGAA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP040334_1

>merge|NZ_CP040334|1|1215012-1215145|CRISPRCasFinder
GACAAATCTCAAAAAGAAGAGAAGTCAACGAGCACGAAACCAGAAAATAAAACAGAAGACAAGTCTCAAAAAGAAGAGAAATCAACAAGCGGTTCAACTAGTGACAAAAAAGAAGAACCGAAGAAAGAAGAAAA

>NZ_CP040334|1|1|1215012-1215145|CRISPRCasFinder
GACAAATCTCAAAAAGAAGAGAA	GTCAACGAGCACGAAACCAGAAAATAAAACAGAA
GACAAGTCTCAAAAAGAAGAGAA	ATCAACAAGCGGTTCAACTAGTGACAAAAAA
GAAGAACCGAAGAAAGAAGAAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040334.1\|WP_157417284.1\|1204504_1206007_+\|NADH-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl\|CDD\|235622
NZ_CP040334.1\|WP_000008903.1\|1215337_1215472_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040334.1\|WP_065485936.1\|1213425_1214130_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|372253
NZ_CP040334.1\|WP_053563324.1\|1220094_1220796_+\|CpsD/CapB-family-tyrosine-protein-kinase	unknown	unknown	gnl\|CDD\|349772
NZ_CP040334.1\|WP_145959727.1\|1218423_1219101_+\|polysaccharide-biosynthesis-tyrosine-autokinase	unknown	unknown	gnl\|CDD\|349772
NZ_CP040334.1\|WP_000544012.1\|1215780_1216053_+\|sporulation-transcriptional-regulator-SpoIIID	unknown	unknown	gnl\|CDD\|378813
NZ_CP040334.1\|WP_157417282.1\|1202645_1204508_+\|NADH-quinone-oxidoreductase-subunit-L	unknown	unknown	gnl\|CDD\|235836
NZ_CP040334.1\|WP_157417290.1\|1212583_1213426_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP040334.1\|WP_000411275.1\|1208763_1210068_+\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|236486
NZ_CP040334.1\|WP_106823501.1\|1220906_1221674_+\|tyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|226870
NZ_CP040334.1\|WP_000057889.1\|1207731_1207968_+\|DUF1146-domain-containing-protein	unknown	unknown	gnl\|CDD\|227173
NZ_CP040334.1\|WP_106823503.1\|1222856_1224665_+\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|224011
NZ_CP040334.1\|WP_157417288.1\|1211394_1212402_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP040334.1\|WP_157417286.1\|1208013_1208724_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370056
NZ_CP040334.1\|WP_081366379.1\|1206008_1207529_+\|NADH-quinone-oxidoreductase-subunit-NuoN	unknown	unknown	gnl\|CDD\|235603
NZ_CP040334.1\|WP_000457978.1\|1216213_1217215_+\|rod-shape-determining-protein	unknown	unknown	gnl\|CDD\|237563
NZ_CP040334.1\|WP_000931959.1\|1217643_1218078_+\|3-hydroxyacyl-ACP-dehydratase-FabZ	unknown	unknown	gnl\|CDD\|234568
NZ_CP040334.1\|WP_053563326.1\|1221914_1222796_+\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|224131
NZ_CP040334.1\|WP_000672651.1\|1210275_1211295_+\|stage-II-sporulation-protein-D	unknown	unknown	gnl\|CDD\|274332
NZ_CP040334.1\|WP_053563323.1\|1219361_1220105_+\|capsular-biosynthesis-protein	unknown	unknown	gnl\|CDD\|226453

Protein	Function_ID	Function_description	E-value
NZ_CP040334.1\|WP_157417284.1\|1204504_1206007_+\|NADH-quinone-oxidoreductase-subunit-M	gnl\|CDD\|235622	PRK05846, PRK05846, NADH:ubiquinone oxidoreductase subunit M; Reviewed.	1.02382e-177
NZ_CP040334.1\|WP_053563323.1\|1219361_1220105_+\|capsular-biosynthesis-protein	gnl\|CDD\|226453	COG3944, COG3944, Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane].	2.81282e-83
NZ_CP040334.1\|WP_065485936.1\|1213425_1214130_+\|ABC-transporter-permease	gnl\|CDD\|372253	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family.	0.0010504
NZ_CP040334.1\|WP_053563324.1\|1220094_1220796_+\|CpsD/CapB-family-tyrosine-protein-kinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	2.81833e-83
NZ_CP040334.1\|WP_145959727.1\|1218423_1219101_+\|polysaccharide-biosynthesis-tyrosine-autokinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	9.54406e-82
NZ_CP040334.1\|WP_000544012.1\|1215780_1216053_+\|sporulation-transcriptional-regulator-SpoIIID	gnl\|CDD\|378813	pfam12116, SpoIIID, Stage III sporulation protein D. This stage III sporulation protein is a small DNA-binding family that is essential for gene expression of the mother-cell compartment during sporulation. The domain is found in bacteria and viruses, and is about 40 amino acids in length. It has a conserved RGG sequence motif.	1.17272e-38
NZ_CP040334.1\|WP_157417282.1\|1202645_1204508_+\|NADH-quinone-oxidoreductase-subunit-L	gnl\|CDD\|235836	PRK06590, PRK06590, NADH:ubiquinone oxidoreductase subunit L; Reviewed.	0
NZ_CP040334.1\|WP_157417290.1\|1212583_1213426_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.10668e-90
NZ_CP040334.1\|WP_000411275.1\|1208763_1210068_+\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl\|CDD\|236486	PRK09369, PRK09369, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated.	0
NZ_CP040334.1\|WP_106823501.1\|1220906_1221674_+\|tyrosine-protein-phosphatase	gnl\|CDD\|226870	COG4464, CapC, Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	7.61927e-107
NZ_CP040334.1\|WP_000057889.1\|1207731_1207968_+\|DUF1146-domain-containing-protein	gnl\|CDD\|227173	COG4836, COG4836, Predicted membrane protein [Function unknown].	1.23409e-23
NZ_CP040334.1\|WP_106823503.1\|1222856_1224665_+\|polysaccharide-biosynthesis-protein	gnl\|CDD\|224011	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	0
NZ_CP040334.1\|WP_157417288.1\|1211394_1212402_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	3.98911e-32
NZ_CP040334.1\|WP_157417286.1\|1208013_1208724_+\|hypothetical-protein	gnl\|CDD\|370056	pfam08680, DUF1779, TATA-box binding. TATA-box_bdg is a family of bacterial proteins. YwmB from Bacillus subtilis contains a circularly permuted TATA-box binding protein-like fold. Jian-Xiang Liu, Qi Xie, Jun Lin. Protein Structural Data Mining and Evolutionary Bioinformatic Analysis on Domains of TATA-box Binding Protein-like Fold. Life Science Journal 2014; 11(2): 298-302 (not yet in PubMed 27-02-2014).	1.34246e-33
NZ_CP040334.1\|WP_081366379.1\|1206008_1207529_+\|NADH-quinone-oxidoreductase-subunit-NuoN	gnl\|CDD\|235603	PRK05777, PRK05777, NADH-quinone oxidoreductase subunit NuoN.	1.12288e-150
NZ_CP040334.1\|WP_000457978.1\|1216213_1217215_+\|rod-shape-determining-protein	gnl\|CDD\|237563	PRK13928, PRK13928, rod shape-determining protein Mbl; Provisional.	0
NZ_CP040334.1\|WP_000931959.1\|1217643_1218078_+\|3-hydroxyacyl-ACP-dehydratase-FabZ	gnl\|CDD\|234568	PRK00006, fabZ, 3-hydroxyacyl-ACP dehydratase FabZ.	5.26499e-95
NZ_CP040334.1\|WP_000672651.1\|1210275_1211295_+\|stage-II-sporulation-protein-D	gnl\|CDD\|274332	TIGR02870, Stage_II_sporulation_protein_D, stage II sporulation protein D. Stage II sporulation protein D (SpoIID) is a protein of the endospore formation program in a number of lineages in the Firmicutes (low-GC Gram-positive bacteria). It is expressed in the mother cell compartment, under control of Sigma-E. SpoIID, along with SpoIIM and SpoIIP, is one of three major proteins involved in engulfment of the forespore by the mother cell. [Cellular processes, Sporulation and germination].	5.30147e-135
NZ_CP040334.1\|WP_053563326.1\|1221914_1222796_+\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	0

>NZ_CP040334.1|WP_065485936.1|1213425_1214130_+|ABC-transporter-permease
MTFSMKRVSAIFRKEVQDFKTNSQVLLMAFLPIILSFLFSRFGVGKEMLGITTITAFLFVAGFVQSMVIAEEKEKHTLRVLMLSPASSVEVLFGKSILTACLTLGICIVNLFILDQFSGNLLLLGFIFLCGTILFIVIGTMIGLLAASVPQTSIIGMPILMTMYLAVQFEPMVENKVIKTMIGYLPTSHIVKALNSLVGGAGFSSISGHVLNVGVWLIIALIACLIVYKKKQMD
>NZ_CP040334.1|WP_157417290.1|1212583_1213426_+|ATP-binding-cassette-domain-containing-protein
MTLAIEMKDVMKSFSGKTALRNVNIEVKQGEIFGFLGPSGSGKTTTVKILTSQLLHSVGTVRVLGKDITGPSSIDYKRIGILTDNSGLYERLSVYDNLLLFCDLYDCKKERINEVLAQVNLLDDKKTPVKKLSKGMKQRVTLARAILHKPDILFLDEPTSALDPVNVQNIHKILKDLNEEGTTIFLTTHNMDEAETLCNRIAFLCSGEIVALDTPENLRLQYAKDQIEVVLKDKQKAVVQKDELGAKRISEWMNKGELLSIHSHEPTLGDIFIEVTGRGL
>NZ_CP040334.1|WP_157417288.1|1211394_1212402_+|ATP-binding-cassette-domain-containing-protein
MALLELKQLGKTNQLPAIELKVEKGQCVVLQCNNHTAKVLHRIIIGEEEASTGNVLFEGEAIGKKNYSRIGFCFLKDEAYDRLKVKEYFKFLLGLYESKISIEEVVQSVGLLDKLNVKIEKLSFSEKRRLHIGRVMIHNPDLVILEEPEQNVDIESTVIIRKAIMKMKEQGKAIFITSSFLSDALSLTEDVYILNNDGVKKIEIEQEEVEEVDEEKVIQMIPQMKLERIPAKVNDKIILLDPMEVHFIETQNGVTHIHVREGDFVCALTLSELEARLTGFGFFRCHRSYLVNLQRVREVITWTRNSFSLILDDERKSSIPLSKGRMDELKGVIGL
>NZ_CP040334.1|WP_000672651.1|1210275_1211295_+|stage-II-sporulation-protein-D
MKFSKPLFITVALLIALVIIVPAALVIPFAKAKVGEETASKTPPAIESIPAPGKVDTAVQVAVYREKQKKVESLPMEEYVTGVVASEMNASFEIEALKAQALAARTFVVQRMLSGGKKNNADVTDTVKDQVYKSKDELKKQWGNNYENNLKKIEEAVSKTAGQVLTYDGKPISASFFSTSNGRTENAADYWGNDYPYLKSVDSPWDQASPKFTSEQTFTVADFQKRLGVKVLADGKVGNIKDLTEGKRVKDVAFQGKTLTGKEVREKLDLRSSDFTWKQQGDKIIVTTKGFGHGVGMSQYGANGMAAEGKKYTDIVAHYYKGVEIKTMNDYEGKLMVKK
>NZ_CP040334.1|WP_000411275.1|1208763_1210068_+|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDSSKELNIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYLDFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGANHSIIPDRIEAGTFMVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQADGTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVGATDLRAAAALILAGLVSEGYTRVTELKHLDRGYVDFHKKLAALGATIERVNEKVEEVKEQEVSDLHA
>NZ_CP040334.1|WP_157417286.1|1208013_1208724_+|hypothetical-protein
MKLKLKAILIVALSIVLFLVGYREMKPISDEQKMESMIKALEKNDAKVEKWSWLARETKTISNIHTFQKLLNDVKDKANIQKWEVEQSPDGYKATSYKKFASHEERVVVTWSKENTKENTFIIFEVSGAKWDPKYVQKVNKIFSEKPIIYTCVQGVLNDKIEGVLQNKTNQVLKDLSARAIEQVEERAFVSVSAYNKKWDDALSTNREKINVQIAIRSTDNKDTIVVGTPIITSEY
>NZ_CP040334.1|WP_000057889.1|1207731_1207968_+|DUF1146-domain-containing-protein
MAQLLGQQALIAIVSHLLFITITWWALQGIHIERLMKSGKVLQTRVLLILITIAIGTSVSNFFLDYLGYSKSLTYLVK
>NZ_CP040334.1|WP_081366379.1|1206008_1207529_+|NADH-quinone-oxidoreductase-subunit-NuoN
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAIVLAIVSLITLYSEPAGDILNGSFVLDGFSKGFKTLLLGASALVLCIAMSDDKKNPIEDKGEYYYLFLMALLGAMFMASSVDFITLFVGLELLSLSSYILVGIRKKNRASNEAAMKYVISGGIGTAITLFGMSYLYGITGSTNIVDMQKVLTGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYEGATTPVTAFLGTISKIAGFLLIIRLFLMVFASVLIQGDMQSLYGHMSIYIAVLASITMIVGNVVALKQYNVKRLFAYSGIAHAGYLLVPLVALSPFTLDSMWFYMLAYMLMNIGAFAIIHGLILQNDKENITIFTGLYKKSPFAAIMMTIFILSLAGIPGTAGFIGKINIFLGALHVEPAHYVLASIMMGTTVVSFVYYFRILQQMFFRTGETEERIRLPLNIKVVMSLCAISIVILGIMPMIGYNFFYEYFPLMKDFFFLGNVVQ
>NZ_CP040334.1|WP_157417284.1|1204504_1206007_+|NADH-quinone-oxidoreductase-subunit-M
MNDLLLTFFIFSPLLGILLLVLTPKKELRTVRALGLFGTALPFGIAIVLACTYASGKSLSLFDEKVKWIKFGDFTAVDKRWFSIYYELGIDGLSLVMMVLTALLAMLAAIAAFSIKRNLKVFYMLLLMLEIGMLGVFAAQNLMLFFIFFEITLPPMFLLIGKWGKLSSEKAAYSYLIYNGIGSAILLIVFSILFAKTGTTNIVELKEILRSVSAEGELIIPSSLQLGVFISIMIAFAIKLPVFPLHRWMVNVHIEAHPAVVMLHAGVLLKIGAYGIIRFGKGLFPEYFHDVATLIAILGVINLLYGAFLALIQTDFRKVLAYSSISHMGIVLMGLASLNAPGTQGALFQVVSHGLIAALLFFLLGVIEQRFGTSEITALGGLAKSVPVLSGFFLAGGMASLGLPGMSGFVSEFLAFLGLFQGEPVIAAVGVIGIILTAVYVLRATLQVTFGKKEWEAKSDIHGWEYVPVLLLIFCIIAIGVMPEILGDPLQNTLKTLGVK
>NZ_CP040334.1|WP_157417282.1|1202645_1204508_+|NADH-quinone-oxidoreductase-subunit-L
MIDYAWLIPLFPLVSFLLLIIFGKKIREGSSILSIFFVFLSFILAVLVLIERFSEASVKHKWVWLRAGDVDISFGFEVTALGALMLFIVTLVSLLVHVYSKGYMKGDERLPTFYAYLGLFTFAMLGLVISTNLLQLYIFWELVGLGSFLLIGFYFFKEEAKAAAKKAFIMTRIGDVGLFIGMILIFWYAGSFEYDAIFRAIYTGDLPPYMITITAILIFIGAMGKSGQFPLHTWLPDAMEGPTPVSALIHAATMVAAGVYLVATMFPLFSASTLAMQTVAIVGAFTAIFAASIGLVQTDIKRVLAYSTVSQLGYMMLALGSAGYVAGVFHLTTHAFFKALLFLAAGSVIHAVHTQNINKMGGLQKKMKVTGTLFLIGTLAISGVPLLSGFFSKDEILAATWMNGNYVLFTLAVIAAFLTAFYMFRLYFLVFTGETKTKEDVHESPRVMTYPMIVLGVLAVVAGYINTPWFGTFLGDWLTKDVGFKVEEAHGPVWIMIVATLVSFAGIALAYFIYGKKSISRDWAGGTETSLYNLLKEKYYVDELYNMTVIPITKGIAHVLRLFEVYVVEGIAVLIGSVVKGTSNLGSKLQNGNVQVYGTVTAVSLAVLVIILLYTGGDLR
>NZ_CP040334.1|WP_000008903.1|1215337_1215472_+|hypothetical-protein
MSFLFVLSTAIILLFVLFTLYYYIAGKKEVPHHQLLEEELEREE
>NZ_CP040334.1|WP_000544012.1|1215780_1216053_+|sporulation-transcriptional-regulator-SpoIIID
MHDYIKERTIKIGKYIVETRKTVRVIAKEFGVSKSTVHKDLTERLPEINPELANEVKEILDYHKSIRHLRGGEATKQKYRKEDVEKPVRQ
>NZ_CP040334.1|WP_000457978.1|1216213_1217215_+|rod-shape-determining-protein
MFARDIGIDLGTANVLIHVKGKGIVLNEPSVVAIDRNSGKVLAVGEEARSMVGRTPGNIVAIRPLKDGVIADFEITEAMLKYFINKLDVKSFFSKPRILICCPTNITSVEQKAIREAAERSGGKTVFLEEEPKVAAVGAGMEIFQPSGNMVVDIGGGTTDIAVLSMGDIVTSSSIKMAGDKFDMEILNYIKRKYKLLIGERTSEDIKIKVGTVFPGARSEELEIRGRDMVTGLPRTITVCSEEITEALKENAAVIVQAAKGVLERTPPELSADIIDRGVILTGGGALLHGIDMLLAEELKVPVLIAENPMHCVAVGTGIMLENIDRLPKRALR
>NZ_CP040334.1|WP_000931959.1|1217643_1218078_+|3-hydroxyacyl-ACP-dehydratase-FabZ
MLNIEQIKEIIPHRYPFLLVDKILEVDEGKRAVGIKNVSANEEFFNGHFPDYAVMPGVLIVEALAQVGAVAVLKKEENRGRLAFFAGIDNCRFKKQVRPGDQLRLEVEMTRVRGPIGKGKAIATVDGEVACEAEITFAIGDKKE
>NZ_CP040334.1|WP_145959727.1|1218423_1219101_+|polysaccharide-biosynthesis-tyrosine-autokinase
MFGRKKRKPLRQLITHKEPKSRITEQYRNIRTNIEFTSVDNHVRSIIVTSADPGDGKTTTIANLAVVFGQQGKKVLLIGADLRKPTIQNLFAIHSSNGLTNLLSGQAKLMQCIQKTDIENVYLMAAGPIPPNPAELLGSRTMDEALLEAYNMFDIILIDTPPVLAVTDAQILANKCDGIVLVVRSEKTEKDKIVKAKQILDKAAGKILGVVLNDKREEKEQYGYY
>NZ_CP040334.1|WP_053563323.1|1219361_1220105_+|capsular-biosynthesis-protein
MEETISLKELFHILKKRLAMILVIAFGAAIVSAIISFFFMTPIYQSSTQILVNQKKQEGAAIQLGEIQSNIQLTNTYKVIIKSPVILDQVNEKLNLNMTAQTLTKKINIANEKDSQVISVTAEDKDPKLARDIANATADVFKDEVAKIMNVDNVTVLSKAEVAENLSPIKPRPMLNVAIAFVVGLMASVGLAFLLEYLDNTVKKEEDVENLLGLPVLGIVARMDEETMNVKSHAPSSRKVRGQTIGS
>NZ_CP040334.1|WP_053563324.1|1220094_1220796_+|CpsD/CapB-family-tyrosine-protein-kinase
MALNLFKKKKNHRQRRQLIAHQQPKSPISEQYRNIRTNIEFAAVDMNLHSLLVTSANPSEGKTTTTANMAVVFAQQGKKVLLIDADMRKPAMHQMFQVDNIFGLTNVLTHSERLEKCVQRTSIDNLSFLACGPIPPNPAELLGSKSMKELLGQAYSMYDLVIFDMPPILAVTDAQIMANVCDASILVVRSESTEKENAVKAKGLLESAKGKLLGVVLNDREREQGLYYYYGAN
>NZ_CP040334.1|WP_106823501.1|1220906_1221674_+|tyrosine-protein-phosphatase
MIDLHCHILPGIDDGAQTVTDSLAMAQQAVAEGIHTIVATPHHQNGKYVNERTPIIHHVKQLNDELQQHNIPLTILPGQEVRLYGDLLEDYEAGKIVTLNETNKYIFIEFPSNHVPRYAEQLLYELRVKGMIPIIVHPERNAELIERPDKLYNLVNKGALTQVTAGSLLGKFGKKIKKFSLQLVEHNLTHMIASDAHNTTSRGFHLAESYELIEKEFGMSVMSDLKENPYLLISGKAIYKEDPEQIRRKKLFGIF
>NZ_CP040334.1|WP_053563326.1|1221914_1222796_+|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIVEEAIESGIEDIIIVTGKGKRAIEDHFDHSFELEQSLLEKGKHEMLEKVQASSKINIHYIRQKEPKGLGHAVWCARKFIGNEPFAVLLGDDIVQAETPCLRQLMDQYEGTQSSVIGVQTVPENETHRYGIIDPIEQSDRRYQVRQFVEKPAQGTAPSSLAIMGRYVLTPEIFMFLENQQTGAGGEIQLTDAIQRLNEVQRVFAYDFEGTRYDVGEKFGFIKTTIEMALQNEELNVELMKYMKEILKKEEVHS
>NZ_CP040334.1|WP_106823503.1|1222856_1224665_+|polysaccharide-biosynthesis-protein
MSYRRRLSLLILLDSFIVLTAVYLSYWFIHPNVLNKIPMTVVISSITLLCSHHVFAAIYKLYNKAWEYASIGELKQIFKAITLSILVTAIVQQIINHDIYVRILAIAWMLHLLLIGGSRFVWRMFRDTYISKATDKKRTLIIGAGSAGTMVVRQLQHNKEADLYPIAFVDDDRNKQKLEIYNVPVIGTTNHIQEIVEDNDIEHIIIAIPSLNRGQINEVFEKCRKTKAKTQIVPMLEDLLDGKVSVNEFRDVQVEDLLGREPVQLDDKGIGEKIKGKTVLITGAGGSIGSEICRQILKYKPAKMVLLGHGENSIYHIEMELRTKYKEQAEFVTEIADIQDRNKIFEIMKKHKPFVVYHAAAHKHVPLMERNPEEAVKNNIIGTKNVAEAADTFGINTFVMVSTDKAVNPTNVMGATKRVAEMVVQHMAMISQTRFVAVRFGNVLGSRGSVIPLFKKQIQSGGPVTVTHPDITRYFMTIPEASRLVIQAGSLARGGELFVLDMGEPVKIADLAKNLIQLSGYSVEEIGIEYSGLRPGEKMYEELLNDNEIYKEQVFPKIHIGKAVLKDFESIQQFIDEFEQMSQENIRKTLLDFANNKVEVNS

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Crispr_ID: NZ_CP040334_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040334_2

2694295-2696607

Orphan

Consensus_repeat	Method
NCCTTGAGGTCCAGTAGC	CRT

34 spacers

The CRISPR arrays of NZ_CP040334_2

>merge|NZ_CP040334|2|2694295-2696607|CRT
GCCTTGAGGTCCGGTAGCACCCGTGTTACCTTGAACGCCTTGAGGTCCAGTAGCACCAGTAGCACCAGTAGCACCTGTGTTACCTTGAGGTCCCTGAGGTCCAGTAGGTCCAGGAGGCCCGCCAGAAGGTCCGGTAGGTCCGGTAACTCCTATACCAGTAGCGCCAGTGGCACCGGTAGCACCTGTGTTACCTTGAACACCTTGAGGTCCAGTAGCACCAGTAGCGCCGGTAGCACCAGTAGCACCTGTGTTACCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCTGTGTTACCTTGAACACCTTGAGGTCCAGTAGCACCAGTAGCACCTGTGTTACCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCTGTGTTACCTTGAACGCCTTGAGGTCCAGTTGCACCGGTAGCACCTGTGTTACCTTGAACGCCTTGAGGTCCAGTAGCACCCGTGTTACCTTGAACACCCTGAGGTCCAGTGGCACCGGTAGCACCTGTGTTACCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCAGTAGCACCTGTGTTACCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCAGTAGCACCTGTGTTACCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCAGTAGCACCTGTGTTACCTTGAACGCCTTGAGGTCCAGTGGCACCAGCAGGTCCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCTGTGTTACCTTGAACACCTTGAGGTCCAGTAGCACCCGTGTTACCTTGAACGCCTTGAGGTCCAGTGGCACCAGTAGCACCCGTGTTACCTTGAACGCCCTGAGGTCCAGTAGCGCCGGTAGCACCAGTAGCACCTGTGTTACCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCTGTGTTACCTTGAACACCTTGAGGTCCAGTAGCACCCGTGTTACCTTGAACGCCTTGAGGTCCAGTGGCACCAGTAGCACCCGTGTTACCTTGAACGCCCTGAGGTCCAGTAGCGCCGGTAGCACCTGTGTTACCTTGAACACCTTGAGGTCCAGTGGCACCAGTAGCACCTGTGTTACCTTGAACGCCTTGAGGTCCAGTGGCACCAGTAGCACCTGTGTTACCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCTGTGTTACCTTGAACACCTTGAGGTCCAGTAGCACCAGTAGCACCTGTGTTACCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCTGTGTTACCTTGAACGCCTTGAGGTCCAGTGGCACCGGTAGCACCTGTGTTACCTTGAACGCCTTGAGGTCCAGTAGCACCCGTGTTACCTTGAACACCCTGAGGTCCAGTGGCACCGGTAGCACCTGTGTTACCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCAGTAGCACCTGTGTTACCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCAGTAGCACCTGTGTTACCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCAGTAGCACCTGTGTTACCTTGAACGCCTTGAGGTCCAGTGGCACCAGCAGGTCCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCTGTGTTACCTTGAACGCCTTGAGGTCCAGTGGCACCAGCAGGTCCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCTGTGTTACCTTGAACACCTTGAGGTCCAGTAGCACCAGTAGCACCTGTGTTACCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCTGTGTTACCTTGAACACCTTGAGGTCCAGTAGCACCCGTGTTACCTTGAACACCTTGAGGTCCAGTGGCACCAGTAGCACCTGTGTTACCTTGAACGCCTTGAGGTCCAGTGGCACCAGTAGCACCTGTGTTACCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCTGTGTTACCTTGAACACCTTGAGGTCCAGTAGCACCAGTAGCACCTGTGTTACCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCTGTGTTACCTTGAACGCCTTGAGGTCCAGTGGCACCAGCAGGTCCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCTGTGTTACCTTGAACACCTTGAGGTCCAGTAGCACCCGTGTTACCTTGAACGCCTTGAGGTCCAGTGGCACCGGTAGCGCCCGTGTTACCTTGAACACCTTGAGGTCCAGTAGCGCCGGTAGCACCTGTGTTACCTTGAGGTCCGGTAGC

>NZ_CP040334|2|1|2694295-2696607|CRT
GCCTTGAGGTCCGGTAGC	ACCCGTGTTACCTTGAACGCCTTGAGGTCCAGTAGCACCAGTAGCACCAGTAGCACCTGTGTTACCTTGAGG
TCCCTGAGGTCCAGTAGG	TCCAGGAGGCCCGCCAGAAGGTCCGGTAGGTCCGGTAACTCCTATACCAGTAGCGCCAGTGGCACCGGTAGCACCTGTGTTACCTTGAAC
ACCTTGAGGTCCAGTAGC	ACCAGTAGCGCCGGTAGCACCAGTAGCACCTGTGTTACCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCTGTGTTACCTTGAAC
ACCTTGAGGTCCAGTAGC	ACCAGTAGCACCTGTGTTACCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCTGTGTTACCTTGAACGCCTTGAGGTCCAGTTGCACCGGTAGCACCTGTGTTACCTTGAAC
GCCTTGAGGTCCAGTAGC	ACCCGTGTTACCTTGAACACCCTGAGGTCCAGTGGCACCGGTAGCACCTGTGTTACCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCAGTAGCACCTGTGTTACCTTGAGC
ACCTTGAGGTCCAGTAGC	GCCGGTAGCACCAGTAGCACCTGTGTTACCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCAGTAGCACCTGTGTTACCTTGAAC
GCCTTGAGGTCCAGTGGC	ACCAGCAGGTCCTTGAGCACCTTGAGGTCCAGTAGCGCCGGTAGCACCTGTGTTACCTTGAACACCTTGAGGTCCAGTAGCACCCGTGTTACCTTGAAC
GCCTTGAGGTCCAGTGGC	ACCAGTAGCACCCGTGTTACCTTGAACGCCCTGAGGTCCAGTAGCGCCGGTAGCACCAGTAGCACCTGTGTTACCTTGAGC
ACCTTGAGGTCCAGTAGC	GCCGGTAGCACCTGTGTTACCTTGAACACCTTGAGGTCCAGTAGCACCCGTGTTACCTTGAAC
GCCTTGAGGTCCAGTGGC	ACCAGTAGCACCCGTGTTACCTTGAACGCCCTGAGGTCCAGTAGCGCCGGTAGCACCTGTGTTACCTTGAAC
ACCTTGAGGTCCAGTGGC	ACCAGTAGCACCTGTGTTACCTTGAACGCCTTGAGGTCCAGTGGCACCAGTAGCACCTGTGTTACCTTGAGC
ACCTTGAGGTCCAGTAGC	GCCGGTAGCACCTGTGTTACCTTGAACACCTTGAGGTCCAGTAGCACCAGTAGCACCTGTGTTACCTTGAGC
ACCTTGAGGTCCAGTAGC	GCCGGTAGCACCTGTGTTACCTTGAACGCCTTGAGGTCCAGTGGCACCGGTAGCACCTGTGTTACCTTGAAC
GCCTTGAGGTCCAGTAGC	ACCCGTGTTACCTTGAACACCCTGAGGTCCAGTGGCACCGGTAGCACCTGTGTTACCTTGAGC
ACCTTGAGGTCCAGTAGC	GCCGGTAGCACCAGTAGCACCTGTGTTACCTTGAGC
ACCTTGAGGTCCAGTAGC	GCCGGTAGCACCAGTAGCACCTGTGTTACCTTGAGC
ACCTTGAGGTCCAGTAGC	GCCGGTAGCACCAGTAGCACCTGTGTTACCTTGAAC
GCCTTGAGGTCCAGTGGC	ACCAGCAGGTCCTTGAGC
ACCTTGAGGTCCAGTAGC	GCCGGTAGCACCTGTGTTACCTTGAAC
GCCTTGAGGTCCAGTGGC	ACCAGCAGGTCCTTGAGC
ACCTTGAGGTCCAGTAGC	GCCGGTAGCACCTGTGTTACCTTGAAC
ACCTTGAGGTCCAGTAGC	ACCAGTAGCACCTGTGTT
ACCTTGAGCACCTTGAGG	TCCAGTAGCGCCGGTAGCACCTGTGTTACCTTGAAC
ACCTTGAGGTCCAGTAGC	ACCCGTGTTACCTTGAAC
ACCTTGAGGTCCAGTGGC	ACCAGTAGCACCTGTGTTACCTTGAAC
GCCTTGAGGTCCAGTGGC	ACCAGTAGCACCTGTGTTACCTTGAGC
ACCTTGAGGTCCAGTAGC	GCCGGTAGCACCTGTGTTACCTTGAAC
ACCTTGAGGTCCAGTAGC	ACCAGTAGCACCTGTGTTACCTTGAGC
ACCTTGAGGTCCAGTAGC	GCCGGTAGCACCTGTGTTACCTTGAAC
GCCTTGAGGTCCAGTGGC	ACCAGCAGGTCCTTGAGC
ACCTTGAGGTCCAGTAGC	GCCGGTAGCACCTGTGTTACCTTGAAC
ACCTTGAGGTCCAGTAGC	ACCCGTGTTACCTTGAAC
GCCTTGAGGTCCAGTGGC	ACCGGTAGCGCCCGTGTTACCTTGAAC
ACCTTGAGGTCCAGTAGC	GCCGGTAGCACCTGTGTT
ACCTTGAGGTCCGGTAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040334.1\|WP_106824344.1\|2702055_2703327_+\|methionine-gamma-lyase-family-protein	unknown	unknown	gnl\|CDD\|311036
NZ_CP040334.1\|WP_023522791.1\|2706208_2706751_+\|DUF1700-domain-containing-protein	unknown	unknown	gnl\|CDD\|285278
NZ_CP040334.1\|WP_000438177.1\|2698847_2699804_+\|stage-V-sporulation-protein-K	unknown	unknown	gnl\|CDD\|163057
NZ_CP040334.1\|WP_043924696.1\|2700788_2702063_+\|GTPase-HflX	unknown	unknown	gnl\|CDD\|274455
NZ_CP040334.1\|WP_000228315.1\|2685271_2685814_+\|DUF420-domain-containing-protein	unknown	unknown	gnl\|CDD\|225204
NZ_CP040334.1\|WP_023522800.1\|2688001_2688913_+\|1-phosphofructokinase	unknown	unknown	gnl\|CDD\|238570
NZ_CP040334.1\|WP_001102628.1\|2705892_2706216_+\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609
NZ_CP040334.1\|WP_000393491.1\|2684641_2684953_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040334.1\|WP_000814431.1\|2692128_2692374_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040334.1\|WP_000450330.1\|2697617_2698583_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271175
NZ_CP040334.1\|WP_000504953.1\|2692554_2693508_+\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	unknown	unknown	gnl\|CDD\|234626
NZ_CP040334.1\|WP_016512432.1\|2688927_2690784_+\|PTS-transporter-subunit-EIIA	unknown	unknown	gnl\|CDD\|236740
NZ_CP040334.1\|WP_106824340.1\|2691133_2692066_+\|SH3-domain-containing-protein	unknown	unknown	gnl\|CDD\|226112
NZ_CP040334.1\|WP_106824338.1\|2687252_2688005_+\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
NZ_CP040334.1\|WP_001179068.1\|2685929_2687093_+\|iron-containing-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|341466
NZ_CP040334.1\|WP_000092763.1\|2703939_2705274_+\|type-I-glutamate--ammonia-ligase	unknown	unknown	gnl\|CDD\|273198
NZ_CP040334.1\|WP_106824346.1\|2706751_2707555_+\|DUF4097-family-beta-strand-repeat-protein	unknown	unknown	gnl\|CDD\|372574
NZ_CP040334.1\|WP_000656783.1\|2703501_2703891_+\|transcriptional-repressor-GlnR	unknown	unknown	gnl\|CDD\|133380
NZ_CP040334.1\|WP_000312267.1\|2700072_2700696_-\|trimeric-intracellular-cation-channel-family-protein	unknown	unknown	gnl\|CDD\|225415
NZ_CP040334.1\|WP_000813896.1\|2693529_2693754_+\|RNA-chaperone-Hfq	unknown	unknown	gnl\|CDD\|179001

Protein	Function_ID	Function_description	E-value
NZ_CP040334.1\|WP_106824344.1\|2702055_2703327_+\|methionine-gamma-lyase-family-protein	gnl\|CDD\|311036	pfam06838, Met_gamma_lyase, Methionine gamma-lyase. This is a putative pyridoxal 5'-phosphate-dependent methionine gamma-lyase enzyme involved in methionine catabolism.	0
NZ_CP040334.1\|WP_023522791.1\|2706208_2706751_+\|DUF1700-domain-containing-protein	gnl\|CDD\|285278	pfam08006, DUF1700, Protein of unknown function (DUF1700). This family contains many hypothetical bacterial proteins and putative membrane proteins.	6.5772e-80
NZ_CP040334.1\|WP_001102628.1\|2705892_2706216_+\|PadR-family-transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	1.79312e-24
NZ_CP040334.1\|WP_043924696.1\|2700788_2702063_+\|GTPase-HflX	gnl\|CDD\|274455	TIGR03156, GTP_HflX, GTP-binding protein HflX. This protein family is one of a number of homologous small, well-conserved GTP-binding proteins with pleiotropic effects. Bacterial members are designated HflX, following the naming convention in Escherichia coli where HflX is encoded immediately downstream of the RNA chaperone Hfq, and immediately upstream of HflKC, a membrane-associated protease pair with an important housekeeping function. Over large numbers of other bacterial genomes, the pairing with hfq is more significant than with hflK and hlfC. The gene from Homo sapiens in this family has been named PGPL (pseudoautosomal GTP-binding protein-like). [Unknown function, General].	0
NZ_CP040334.1\|WP_000228315.1\|2685271_2685814_+\|DUF420-domain-containing-protein	gnl\|CDD\|225204	COG2322, COG2322, Predicted membrane protein [Function unknown].	9.14687e-57
NZ_CP040334.1\|WP_023522800.1\|2688001_2688913_+\|1-phosphofructokinase	gnl\|CDD\|238570	cd01164, FruK_PfkB_like, 1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose 6-phosphate pathway, which responsible for breakdown of the galactose moiety during lactose metabolism by bacteria such as L. lactis.	3.71729e-143
NZ_CP040334.1\|WP_106824346.1\|2706751_2707555_+\|DUF4097-family-beta-strand-repeat-protein	gnl\|CDD\|372574	pfam13349, DUF4097, Putative adhesin. This has a putative all-beta structure with a twenty-residue repeat with a highly conserved repeating GD, gly-asp, motif. It may form part of a bacterial adhesin.	2.61672e-19
NZ_CP040334.1\|WP_000438177.1\|2698847_2699804_+\|stage-V-sporulation-protein-K	gnl\|CDD\|163057	TIGR02881, Stage_V_sporulation_protein_K, stage V sporulation protein K. Members of this protein family are the stage V sporulation protein K (SpoVK), a close homolog of the Rubisco expression protein CbbX (TIGR02880) and a members of the ATPase family associated with various cellular activities (pfam00004). Members are strictly limited to bacterial endospore-forming species, but are not universal in this group and are missing from the Clostridium group. [Cellular processes, Sporulation and germination].	1.36822e-156
NZ_CP040334.1\|WP_000450330.1\|2697617_2698583_-\|site-specific-integrase	gnl\|CDD\|271175	cd00397, DNA_BRE_C, DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine based site-specific recombinases (integrases) that share the same fold in their catalytic domain containing conserved active site residues. The best-studied members of this diverse superfamily include Human topoisomerase I, the bacteriophage lambda integrase, the bacteriophage P1 Cre recombinase, the yeast Flp recombinase, and the bacterial XerD/C recombinases. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. The enzymes differ in that topoisomerases cleave and then rejoin the same 5' and 3' termini, whereas a site-specific recombinase transfers a 5' hydroxyl generated by recombinase cleavage to a new 3' phosphate partner located in a different duplex region. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	1.54948e-12
NZ_CP040334.1\|WP_000504953.1\|2692554_2693508_+\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	gnl\|CDD\|234626	PRK00091, miaA, tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed.	1.35751e-163
NZ_CP040334.1\|WP_016512432.1\|2688927_2690784_+\|PTS-transporter-subunit-EIIA	gnl\|CDD\|236740	PRK10712, PRK10712, PTS system fructose-specific transporter subunits IIBC; Provisional.	7.05725e-144
NZ_CP040334.1\|WP_106824340.1\|2691133_2692066_+\|SH3-domain-containing-protein	gnl\|CDD\|226112	COG3584, COG3584, Uncharacterized protein conserved in bacteria [Function unknown].	2.67404e-36
NZ_CP040334.1\|WP_106824338.1\|2687252_2688005_+\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	2.30093e-81
NZ_CP040334.1\|WP_001179068.1\|2685929_2687093_+\|iron-containing-alcohol-dehydrogenase	gnl\|CDD\|341466	cd08187, BDH, Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process. The butanol dehydrogenase (BDH) is involved in the final step of the butanol formation pathway in anaerobic micro-organism. Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process. Activity in the reverse direction is 50-fold lower than that in the forward direction. The NADH-BDH has higher activity with longer chained aldehydes and is inhibited by metabolites containing an adenine moiety. This protein family belongs to the so-called iron-containing alcohol dehydrogenase superfamily. Since members of this superfamily use different divalent ions, preferentially iron or zinc, it has been suggested to be renamed to family III metal-dependent polyol dehydrogenases. This family also includes E. coli YqhD enzyme, an NADP-dependent dehydrogenase whose activity measurements with several alcohols demonstrate preference for alcohols longer than C3. The active site of YqhD contains a Zn metal, and a modified NADPH cofactor bearing OH groups on the saturated C5 and C6 atoms, possibly due to oxygen stress on the enzyme, which would functionally work under anaerobic conditions.	0
NZ_CP040334.1\|WP_000092763.1\|2703939_2705274_+\|type-I-glutamate--ammonia-ligase	gnl\|CDD\|273198	TIGR00653, Glutamine_synthetase, glutamine synthetase, type I. Alternate name: glutamate--ammonia ligase. This model represents the dodecameric form, which can be subdivided into 1-alpha and 1-beta forms. The phylogeny of the 1-alpha and 1-beta forms appears polyphyletic. E. coli, Synechocystis PCC6803, Aquifex aeolicus, and the crenarcheon Sulfolobus acidocaldarius have form 1-beta, while Bacillus subtilis, Thermotoga maritima, and various euryarchaea has form 1-alpha. The 1-beta dodecamer from the crenarcheon Sulfolobus acidocaldarius differs from that in E. coli in that it is not regulated by adenylylation. [Amino acid biosynthesis, Glutamate family].	0
NZ_CP040334.1\|WP_000656783.1\|2703501_2703891_+\|transcriptional-repressor-GlnR	gnl\|CDD\|133380	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators. Helix-turn-helix (HTH) transcription regulator GlnR and related proteins, N-terminal domain. The GlnR and TnrA (also known as ScgR) proteins have been shown to regulate expression of glutamine synthetase as well as several genes involved in nitrogen metabolism. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	1.14369e-23
NZ_CP040334.1\|WP_000312267.1\|2700072_2700696_-\|trimeric-intracellular-cation-channel-family-protein	gnl\|CDD\|225415	COG2860, COG2860, Predicted membrane protein [Function unknown].	1.8015e-60
NZ_CP040334.1\|WP_000813896.1\|2693529_2693754_+\|RNA-chaperone-Hfq	gnl\|CDD\|179001	PRK00395, hfq, RNA-binding protein Hfq; Provisional.	3.4363e-41

>NZ_CP040334.1|WP_000813896.1|2693529_2693754_+|RNA-chaperone-Hfq
MKQSINIQDQFLNQLRKENTFVTLYLLNGFQLRGLIKGFDNFTVLLETEGKQQLIYKHAISTFVPQKNVSIELE
>NZ_CP040334.1|WP_000504953.1|2692554_2693508_+|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA
MGEVQREKVAVIIGPTAVGKTKLSIDLAKALNGEIISGDSMQIYRTMDIGTAKVTQAEMDGIPHYMVDIKNPEDSFSVAEFQERVRKHIREITERGKLPIIVGGTGLYIQSVLFDYQFTDDAGDVIYREQMEKLALERGVEYVHKKLQEVDPESAERIHANNVRRVIRALEIFHTTGEKMSDQIEKQEKELLYDVSLIGLTMDREMLYDRINLRVDLMMEQGLLEEVEGLYNRGIRDCQSIQAIGYKEIYDYFENRAPLEDAVSQLKTNSRRYAKRQLTWFRNKMDVTWFDVTDGEKTSEILRYIEGKLQVKSNNSK
>NZ_CP040334.1|WP_000814431.1|2692128_2692374_-|hypothetical-protein
MKQSTINFSSLTKDLILATSTKEQNCSQEELYFALNCLLRAFHSTLHETTSHPENKNTEYIQTQFCSAYKIITGKTIYPFQ
>NZ_CP040334.1|WP_106824340.1|2691133_2692066_+|SH3-domain-containing-protein
MKKLLSIATAAVFGLGIFAGSAKAETIVTTDVLNVRENPNVESKLVGKVLSGNTLDVINTENGWTKIKLNGKEAFVSADFTKSTYYVTAGVLNVRAGANTDSEILGKLNKNDVIETTNQVQNEWLQFDYNGKVGYVHVPFLTGTAPVIEKKEVVVQEEAPVKNNTAVKNKESVKSNDSIKNVESSKPVVKEKPAAKPVAKSTETSAPTSGREITVEATAYTADPSENGSYGGRVLTAMGHDLTANPNMKVIAVDPKVIPLGSKVWVEGYGEAIAGDTGGAIKGNRIDVLVGSDGSANSWGRKSVKVKVIQ
>NZ_CP040334.1|WP_016512432.1|2688927_2690784_+|PTS-transporter-subunit-EIIA
MKITELLKRDTVIMDLTASNKEAVIDELVEKLNGANRLNSKTEFKEAILKRESQSTTGIGEGIAIPHAKTKAVKQPSICFGRSVSGINYESLDGQPAYLFFMIAASEGANNTHLETLSRLSTLLMDEGFRKQLLEAKDESELLQLFDEKENEKEEEIEVAQPEGNEPYVLAVTACPTGIAHTYMAADSLKAKAAELGIAIKVETNGSTGIKNGLTKEDIERATAIIVAADKQVEMNRFAGKHVIQVPVADGIRKTEKLLNRAVKQDAPIFKGVKEDGKSESIEREKGLGIYKHLMSGVSNMLPFVVGGGILIALAFSFGGIKAEGPLAELFMSIGGGKTGAFLFLVPILAGFIASSIADRPGFMPGVVGGFLAANANAGFLGGLIAGFLAGYVVLGLKRLFSGLPVQLEGIKPVLLYPVFGLLITGVVMQKVVIPPVVALNEMLTGWLNGLNGTNAILLGLILGGMMAIDMGGPINKAAFTFGIAAIEAQNFGVHSAVMAGGMVPPLAIAFATTFFKSKFTEAERKSGLTNYIMGASFITEGAIPFAAADPVRVIVSCVVGSSIAGALSMLFQITLPAPHGGLFVIALVNKPLLYIFSILIGTIVSAIMLGVWKKKVQ
>NZ_CP040334.1|WP_023522800.1|2688001_2688913_+|1-phosphofructokinase
MIYTVTLNPSIDYVVQVPSFDLGTINRAEKDMKFPGGKGINVSRVLQRLGVKNIALGFTGGFTGQFIKEVLHDEGVTTNFVQVDEDTRINVKIKGKEETELNGQGPIVTKEQFEQLMKKIESMQPGDCVVLAGSVPVSIPSTFYESIAAFGAEKGIRVVVDASGSALQHVIKNKPFLIKPNHHELGELFGVELSTVEDILPYGRKLIEQGVKHVIVSMAGEGALLFTAEGIYEATVPKGVVINSVGAGDSLVAGFVGKYEQTKDIEKAFQYGVATGSATAFSADLCKKEKVEELLSQVIVAKR
>NZ_CP040334.1|WP_106824338.1|2687252_2688005_+|DeoR/GlpR-transcriptional-regulator
MLTPERHQMILQLVKEQKVVKLQQLVERTESSESTIRRDLAQLEKQRLLKRVHGGAAVLTGKGQEPTMVEKSSKNIQIKQQIANYAASVVEQGDCIYLDAGSTTFEMIPFLINKDVTVVTNGLMHIEALVENNIRAYLLGGMMKSRTKALIGAMAQESMQKYRFDKCFLGANGVHEQFGFTTPDPEEALLKQMALTLANEGYFLIDESKFSEVAFAKIANVEDANIITNHLEIDLEKYKKQTNVIEADKQ
>NZ_CP040334.1|WP_001179068.1|2685929_2687093_+|iron-containing-alcohol-dehydrogenase
MQNFVFRNPTKLIFGKDQLEQLKTEIPQFGKKVLLVYGGGSIKRNGIYDNVISILKDINAEVFELTGVEPNPRVSTVKKGIQICKDNGVEFILAVGGGSVIDCTKAIAAGSKYDGDVWDIVTKKAFASEALPFGTVLTLAATGSEMNAGSVITNWETNEKYGWGSPVTFPQFSILDPVHTASVPRDQTIYGMVDIMSHVLEQYFHHGTNTELQDRYCESVLKTVIETAPKLLSDLENYEHRETILYCGTMALNGILAMGVRGDWATHNIEHAVSAVHDIPHGGGLAILFPNWMKHVVDENVSRFKQFAIRVFEIETDGKTDKEVALEGIEALRQFWTSIEAPATLADYGIGENEIDIMANKAMAYGEFGNFKKLNKDDVLSIYKASL
>NZ_CP040334.1|WP_000228315.1|2685271_2685814_+|DUF420-domain-containing-protein
MVDQSTNQKSYAPIVITLSVIVNAIILFLFFGPVGYEGEVHFDVTILPMLNAIFNSFTFVFLLAALFSIIKKNVKMHRGFILAAFTTTLLFCVSYLSYHYLAPATHFGGEGFIKYVYFIILITHIILAAIIVPLALFALVFGFTNQLTRHRKIVRWTMPIWLYVSLSGVIVYLMISPYYQ
>NZ_CP040334.1|WP_000393491.1|2684641_2684953_+|hypothetical-protein
MEEYVLELYNLLYTTEWQDIVSFLGIVFCMKIVIVYMEEQGMFYSFSSPFDVQREPLLNYANVNYEQFPFVVFFMIRFITAIVKKKESDDEECHATCKVANVF
>NZ_CP040334.1|WP_000450330.1|2697617_2698583_-|site-specific-integrase
METTEFHDTIQAFSIFLLNKGRKPSTIKRYVYDVEDFGHWLEKNKKLPSSNIWATLCTKDYEDYFSDLKTNRHYSEKTMHRVFTVLNRMHHFLNIPNPLKNMEISIQPDRTLRNEDFISPDEEKRLKYIVTSLEGLSEKQLPVRPLLMDRNIAILNLLIDYGLSLQELTALTMHHVHFETNTLSIPATAGVERTITLAKEDKKQLYNYYKSIPEPVRPKYHSDDSLFVAFDFNRGTYRWVYENDAPKALTEIAIQKMIRLEVARANLRKGISGQHFRNTYILNLIKKETPESEIIKLAGFKSKISLKRYYQYAENRKNALL
>NZ_CP040334.1|WP_000438177.1|2698847_2699804_+|stage-V-sporulation-protein-K
MEQSMRKKNNNQINIVLNHRKKISLPAAENKTVISNETTIKHEMLQRIEEEMGKLVGMDDIKKIIKEIYAWIYVNKKRQEKGLKSEKQVLHMLFKGNPGTGKTTVARMIGKLLFEMNILSKGHLVEAERADLVGEYIGHTAQKTRDLIKKAMGGILFIDEAYSLARGGEKDFGKEAIDTLVKHMEDKQHGFVLILAGYSREMNHFLSLNPGLQSRFPFIIEFADYSVNQLLEIGKRMYEDREYQLSKEAEWKFRDHLHAVKYSSQITSFSNGRYVRNIVEKSIRTQAMRLLQEDTYDKNDLIGISSMDLMLEEETHST
>NZ_CP040334.1|WP_000312267.1|2700072_2700696_-|trimeric-intracellular-cation-channel-family-protein
MAWEIFSIIGTIAFALSGAIVAMEEDYDIFGVYILGMATAFGGGALRNLLIGYPIVAFWQQDMLFQIALLSMTIIFLFPNKLIRHWKKWENITDAIGLSAFAVQGALYAQKLNLPISATIVAAVLTGIGGGIIRDLLARRKPLVLRAEVYAFWTILAGFLIGAQIIVSDWALYILFILIVCFRMVSIHYKWHLPHRRIETKERSMHK
>NZ_CP040334.1|WP_043924696.1|2700788_2702063_+|GTPase-HflX
MEEKEKVILVGCQLPQDDDEKFMHSMKELASLAKTARAEVLVSTTQKRPKFHPATYIGKGKLEELTMLTEELEPDVIIFNNELTPSQIRNLSSVLDARVIDRTQLILDIFAQRAKSREGKLQVELAQLQYTMPRLMGQGLSLSRLGGGIGTRGPGETKLETDRRHIRSRIDEIKKQLAVVVEHRKRYRERRKDNKVFQISLIGYTNAGKSTLFNRLTEANTFEENLLFATLDPTTRKMPLPSGYTVLLTDTVGFIQDLPTSLIAAFRSTLEEAGEADVILHVVDSADPNYIGHEKTVKRLLSELEINHIPIITLYNKKDELHQNFIPFPKSDFLMTSAFEESDLLRIKEAIEMKMKKEMDRYRVEIPPSEGKLLTLLKTETLLAKMEFLEDKFVYDCAGYIFTHSSLNVQLKRFLVEEGENKNV
>NZ_CP040334.1|WP_106824344.1|2702055_2703327_+|methionine-gamma-lyase-family-protein
MFDRLKNGEKIAPIVKEVENQITEVHKRADEVIESNQFRVLESFRKHKISDSHFIPTTGYGYDDIGRDTLEKVYADVFGAEAGLVRPQIISGTHAISTALFGILRPGDELLYITGKPYDTLEEIVGVRGKGVGSFKEYNIGYNAVPLTEGGLVDFEAVAAAIHSNTKMIGIQRSKGYATRPSFTISQIKEMIAFVKEIKPDVVVFVDNCYGEFIEEQEPCHVGADLMAGSLIKNPGGGIVKTGGYIVGKEQHVEACAYRLTSPGIGAEAGASLYSLQEMYQGFFLAPHVAGQALKGAIFTAAFLEKLGMNTSPAWNAPRTDLIQSVQFDDKDRMVAFCQAIQYASPINSHFTPYANYMPGYEDDVIMAAGTFIQGASIELSADGPIRPPYVAYVQGGLTYSHVKIAICSAIDELIEKNLLTIS
>NZ_CP040334.1|WP_000656783.1|2703501_2703891_+|transcriptional-repressor-GlnR
MKEDRRSAPLFPIGIVMDLTQLSARQIRYYEEHNLVSPTRTKGNRRLFSFNDVDKLLEIKDLLDQGLNMAGIKQVLLMKENQTEAVKVKEETKEISKTELRKILRDELQHTGRFNRTSLRQGDISRFFH
>NZ_CP040334.1|WP_000092763.1|2703939_2705274_+|type-I-glutamate--ammonia-ligase
MSRYTKEDIFRLAKEENVKYIRLQFTDLLGVIKNVEIPVRQLTKALDNKMMFDGSSIEGFVRIEESDMYLYPDLDTWVIFPWTAEKGKVARLICDIYNADGTPFDGDPRNNLKRVLKEMEALGFSDFNLGPEPEFFLFKVDEKGNPTLELNDNGGYFDLAPMDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYANAIRSCDDIQTFKLVVKTIARKHGLHATFMPKPLYGVNGSGMHCNLSLFKNGENVFFDANGDLQLSDDARHFIAGILKHAPAFTAIANPTVNSYKRLVPGYEAPCYVAWSAQNRSPLVRIPASRGISTRVEVRSVDPAANPYLVMATLLAAGLDGIKNKLTPPAAVDRNIYVMTKEEREEAGIVDLPATLAQALVTLQSNEVVCGALGEHLLEHFIEAKEIEWDIFRTQVHQWERDQYMSLY
>NZ_CP040334.1|WP_001102628.1|2705892_2706216_+|PadR-family-transcriptional-regulator
MNVQFKKGVLELCVLALVKRKDSYGYELVQQISNKFLISEGSVYPLLRRLTKEGYFQTYLKESTEGPPRKYYQLTEQGETQFHLLVTEWRDFAKGVQEIIEGVEWDE
>NZ_CP040334.1|WP_023522791.1|2706208_2706751_+|DUF1700-domain-containing-protein
MSKEGFLKELLSYLRKLPEEERQDILLDYEEHFQFGLEEGKTESEIIQGLGSPKVIAKELLAMYRFDEMKKNPSTSNVTRAVMAAIGLSLFNFIIVLGPLVAIVAFIFSFWIGGIASVVTPFFVIGKVFMGTFIWLDLFVSITFVGVGLLLCIIAFYSTKWFKRLCVRYVIWNFKMIKGE
>NZ_CP040334.1|WP_106824346.1|2706751_2707555_+|DUF4097-family-beta-strand-repeat-protein
MMKKLFLIAIACIIIGVIGISQTYEKAVQTAEKGDKEDVIKNETLKNIEVKLDAGDIVIQKSPDSSFYVKQSGDVRKQEIRIAEDGDTLKIIGERKKGASFDFSFYDFRFQTSKLTLLVPERSYQDVKVNSSAGQIEMSDVKSDSVSVRTLAGEVELKQVTAKNVEGSTKAGEVNFKKVLGKVTAKTKSGEINIQDHDSKYNLEASSTAGDIDITLSEKPQDAVITGQSAAGDVTIFNEENNNVTIGNGSKKISGKTAAGDVTIETR

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Crispr_ID: NZ_CP040334_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP040334_3

5238665-5238757

Orphan

Consensus_repeat	Method
CCATCTACTAATTTTCCGATACCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP040334_3

>merge|NZ_CP040334|3|5238665-5238757|CRISPRCasFinder
CCATCTACTAATTTTCCGATACCTGCATTGCTATTTAATACATGTAAACCATCTGTTACTTTTCCTGATCCATCTACTAATTTCCCGATACCT

>NZ_CP040334|3|2|5238665-5238757|CRISPRCasFinder
CCATCTACTAATTTTCCGATACCT	GCATTGCTATTTAATACATGTAAACCATCTGTTACTTTTCCTGAT
CCATCTACTAATTTCCCGATACCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040334.1\|WP_106822860.1\|5247030_5248383_+\|DUF4026-domain-containing-protein	unknown	unknown	gnl\|CDD\|338635
NZ_CP040334.1\|WP_106822848.1\|5235124_5235634_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP040334.1\|WP_000726775.1\|5249880_5250816_-\|ferrochelatase	unknown	unknown	gnl\|CDD\|183526
NZ_CP040334.1\|WP_106822846.1\|5231243_5231672_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040334.1\|WP_157418232.1\|5244422_5246789_-\|endonuclease	unknown	unknown	gnl\|CDD\|225249
NZ_CP040334.1\|WP_106822852.1\|5236456_5236669_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040334.1\|WP_000184509.1\|5242425_5242827_-\|BlaI/MecI/CopY-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|367747
NZ_CP040334.1\|WP_001068222.1\|5235767_5236121_+\|PlcR-regulated-protein-PRP2	unknown	unknown	gnl\|CDD\|379617
NZ_CP040334.1\|WP_157418233.1\|5248439_5249861_-\|protoporphyrinogen-oxidase	unknown	unknown	gnl\|CDD\|237009
NZ_CP040334.1\|WP_106822854.1\|5240509_5242423_-\|M48-family-metalloprotease	unknown	unknown	gnl\|CDD\|310280
NZ_CP040334.1\|WP_000963381.1\|5239724_5240297_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP040334.1\|WP_106822850.1\|5236147_5236453_-\|DUF2087-domain-containing-protein	unknown	unknown	gnl\|CDD\|226378
NZ_CP040334.1\|WP_106822856.1\|5243996_5244296_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040334.1\|WP_000103715.1\|5233916_5234930_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NZ_CP040334.1\|WP_064532829.1\|5243056_5243911_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP040334.1\|WP_000784690.1\|5232810_5233545_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293802
NZ_CP040334.1\|WP_000567010.1\|5233748_5233877_+\|YhfH-family-protein	unknown	unknown	gnl\|CDD\|379490
NZ_CP040334.1\|WP_000252605.1\|5250830_5251877_-\|uroporphyrinogen-decarboxylase	unknown	unknown	gnl\|CDD\|234644
NZ_CP040334.1\|WP_000897273.1\|5231811_5232801_-\|lipoate--protein-ligase	unknown	unknown	gnl\|CDD\|161920
NZ_CP040334.1\|WP_001055178.1\|5229549_5231082_-\|fatty-acid--CoA-ligase-family-protein	unknown	unknown	gnl\|CDD\|236072

Protein	Function_ID	Function_description	E-value
NZ_CP040334.1\|WP_106822860.1\|5247030_5248383_+\|DUF4026-domain-containing-protein	gnl\|CDD\|338635	pfam13218, DUF4026, Protein of unknown function (DUF4026). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 450 amino acids in length. The family is found in association with pfam10077.	3.41396e-177
NZ_CP040334.1\|WP_106822848.1\|5235124_5235634_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	9.20273e-14
NZ_CP040334.1\|WP_000726775.1\|5249880_5250816_-\|ferrochelatase	gnl\|CDD\|183526	PRK12435, PRK12435, ferrochelatase; Provisional.	0
NZ_CP040334.1\|WP_157418233.1\|5248439_5249861_-\|protoporphyrinogen-oxidase	gnl\|CDD\|237009	PRK11883, PRK11883, protoporphyrinogen oxidase; Reviewed.	0
NZ_CP040334.1\|WP_000184509.1\|5242425_5242827_-\|BlaI/MecI/CopY-family-transcriptional-regulator	gnl\|CDD\|367747	pfam03965, Penicillinase_R, Penicillinase repressor. The penicillinase repressor negatively regulates expression of the penicillinase gene. The N-terminal region of this protein is involved in operator recognition, while the C-terminal is responsible for dimerization of the protein.	1.71375e-45
NZ_CP040334.1\|WP_001068222.1\|5235767_5236121_+\|PlcR-regulated-protein-PRP2	gnl\|CDD\|379617	pfam14470, bPH_3, Bacterial PH domain. Proteins in this family are distantly related to PH domains.	1.38357e-18
NZ_CP040334.1\|WP_106822854.1\|5240509_5242423_-\|M48-family-metalloprotease	gnl\|CDD\|310280	pfam05569, Peptidase_M56, BlaR1 peptidase M56. Production of beta-Lactamase and penicillin-binding protein 2a (which mediate staphylococcal resistance to beta-lactam antibiotics) is regulated by a signal-transducing integral membrane protein and a transcriptional repressor. The signal transducer is a fusion protein with penicillin-binding and zinc metalloprotease domains. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription. homologs to this peptidase domain, which corresponds to Merops family M56, are also found in a number of other bacterial genome sequences.	1.58476e-50
NZ_CP040334.1\|WP_000963381.1\|5239724_5240297_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.571e-14
NZ_CP040334.1\|WP_106822850.1\|5236147_5236453_-\|DUF2087-domain-containing-protein	gnl\|CDD\|226378	COG3860, COG3860, Uncharacterized protein conserved in bacteria [Function unknown].	8.64317e-24
NZ_CP040334.1\|WP_157418232.1\|5244422_5246789_-\|endonuclease	gnl\|CDD\|225249	COG2374, COG2374, Predicted extracellular nuclease [General function prediction only].	1.46685e-72
NZ_CP040334.1\|WP_000103715.1\|5233916_5234930_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	2.56346e-114
NZ_CP040334.1\|WP_000784690.1\|5232810_5233545_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293802	cd07716, RNaseZ_short-form-like_MBL-fold, uncharacterized bacterial subgroup of Ribonuclease Z, short form; MBL-fold metallo-hydrolase domain. The tRNA maturase RNase Z (also known as tRNase Z or 3' tRNase) catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors. Two forms of RNase Z exist in eukaryotes, one long (ELAC2) and one short form (ELAC1), the former may have resulted from a duplication of the shorter enzyme. Only the short form exists in bacteria. Members of this bacterial subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	3.54816e-86
NZ_CP040334.1\|WP_000567010.1\|5233748_5233877_+\|YhfH-family-protein	gnl\|CDD\|379490	pfam14149, YhfH, YhfH-like protein. The YhfH-like protein family includes the B. subtilis YhfH protein, which is functionally uncharacterized. Its expression is repressed by the Spx paralogue MgsR, which regulates genes involved in stress response. This family of proteins is found in bacteria. Proteins in this family are typically between 42 and 53 amino acids in length.	3.52581e-13
NZ_CP040334.1\|WP_000252605.1\|5250830_5251877_-\|uroporphyrinogen-decarboxylase	gnl\|CDD\|234644	PRK00115, hemE, uroporphyrinogen decarboxylase; Validated.	0
NZ_CP040334.1\|WP_000897273.1\|5231811_5232801_-\|lipoate--protein-ligase	gnl\|CDD\|161920	TIGR00545, Probable_lipoate-protein_ligase_A, lipoyltransferase and lipoate-protein ligase. One member of this group of proteins is bovine lipoyltransferase, which transfers the lipoyl group from lipoyl-AMP to the specific Lys of lipoate-dependent enzymes. However, it does not first activate lipoic acid with ATP to create lipoyl-AMP and pyrophosphate. Another member of this group, lipoate-protein ligase A from E. coli, catalyzes both the activation and the transfer of lipoate. Homology between the two is full-length, except for the bovine mitochondrial targeting signal, but is strongest toward the N-terminus. [Protein fate, Protein modification and repair].	7.43634e-139
NZ_CP040334.1\|WP_001055178.1\|5229549_5231082_-\|fatty-acid--CoA-ligase-family-protein	gnl\|CDD\|236072	PRK07656, PRK07656, long-chain-fatty-acid--CoA ligase; Validated.	0

>NZ_CP040334.1|WP_106822852.1|5236456_5236669_-|hypothetical-protein
MMRGNLTYYFIVNPLIIFLVYALSPILFDKEVYTSMKDAFGILTFYYVLMGGYYFIDILSEKIKKKTDGG
>NZ_CP040334.1|WP_106822850.1|5236147_5236453_-|DUF2087-domain-containing-protein
MTESEMKFRDMTIRNFFDKEDRLKSIPGQKKKKLVLLEHLISKLNAENQYTEKEINTFIKQYHDDFCTIRREFIVQGFMDREDNMYRINGREVWTKWEELK
>NZ_CP040334.1|WP_001068222.1|5235767_5236121_+|PlcR-regulated-protein-PRP2
MNPILTAAKQLLHKEEKILSTLKCSLTGYMITHKVPYRGMLLATNRRLLFFSQYKNTFIAEFDYEKILSVETKRRIFDKKIIFYYEDEYITLGYITSSNVEAFIDLLQRNSKTSTGL
>NZ_CP040334.1|WP_106822848.1|5235124_5235634_-|GNAT-family-N-acetyltransferase
MIRLVKETDAEAIMNIRKEIILSEITTKFFIVSPKKLPNDIDVEREKIRKSNEKGNLYIVYEVDYKVVGFLLFNRYELERLQHAGTMGMGIKEAYCNQGIGTKLIEFLISWAKGQKGLEKICLGVVSVNDRAIKVYKRMGFVEEGRQRKQIKYEDGSYGDDVLMGFYIE
>NZ_CP040334.1|WP_000103715.1|5233916_5234930_-|LacI-family-DNA-binding-transcriptional-regulator
MSTIEDVAKLAGLSRTTVSRVINNHPYVSDEKKKRVQLAMKHLGFVPNSAARRLRKQKTETIAVLVPRITNPFFSRFIEAIEIAASEHKYKLIICQTRYLPEKEMEYLQLLSTKQVDGIILCSLENPWEDVEPYLQHGPIVLCNEYIEEANIPTVKFDHAQGAYIAAKHVLDQGYRNLIFCRGNETKVVSQQRKMGFLRAITEKSRQVEAIDFLENAFSWEDGKRIFHEVLKDKKNPTAILAGGDEVAAGIISEAKRHNWSIPDDLAVIGFDNQILSQITEPGITTIEQPIDEMARKVVDLMMDKIHTKNYRKKELYEFELELLVKGSTMKDKMLLA
>NZ_CP040334.1|WP_000567010.1|5233748_5233877_+|YhfH-family-protein
MIDQPMEFFRNLPTKTCAHCGKEIDEQHEAYHNKCDDCVHEE
>NZ_CP040334.1|WP_000784690.1|5232810_5233545_-|MBL-fold-metallo-hydrolase
MKMTVVGFWGGFPEAGEATSGYLFEHDGFRLLVDCGSGVLAQLQKYITPSHIDAVVLSHYHHDHVADIGVLQYARLITSATTRQLPELPIYGHTFDENGFHSLTHEPHTKGIAYNPEETLQVGPFSISFLKTVHPVTCFAMRITAGDDAVVYSADSSYIPEFIPFTKDADLFICECNMYAHQEAAKAGHMNSTEVASIAKDANVKELLLTHLPHTGNPSDLVTEAKQIFSGHITLAHSGYVWNS
>NZ_CP040334.1|WP_000897273.1|5231811_5232801_-|lipoate--protein-ligase
MLFIDNKGITDPRINLAIEEYCVKNLDINETYLLFYINEPSIIIGKNQNTVEEINADYVKEKGIHVVRRLSGGGAVYHDLGNLNFSFITKDDGDSFSNFKKFTEPVTKALSKLGVKAELSGRNDILAEGRKISGNAQFSTKGRMFSHGTLLFDSEIDHVVSALKVKMDKIQSKGIKSIRSRVANITEFLNEEMTTEEFRQLLLETIFEGETEIPTYELTENDWKEIHKLSEERYQNWDWNYGKSPKFNLQHSHRFPVGQVDVRLEVKKGTVTECKIYGDFFGSLDVHDIEERLTGVQFDKDAFTAALEGVDIARYFGNITTEDFLHLFF
>NZ_CP040334.1|WP_106822846.1|5231243_5231672_-|hypothetical-protein
MKRVIHIVILLGFVIGIAACNSETSSSRTLLYIGKPAEDNVIYFTHTDNKRKIHNIQDMFQNKKWKRNETFSTVNKTPDVVLSIDENNKGLPTLYVTVYFHENGADVLNLYGEYTNLNKEELEKLKEKMSAYYPKMIFGLVL
>NZ_CP040334.1|WP_001055178.1|5229549_5231082_-|fatty-acid--CoA-ligase-family-protein
MNLVQSLAETAKKKGDKPAYIFMDQSVSYDQLNKMVTRFSSNLAEMGIGKGDNVALVVGNSPHFLVGLYGTMKAGATVIPVNPIYTADEMHYILQNGDVKTIIVLDVLLPVIQSLTTRLPSLENIIICETSSDFNHTETEKMKTFTSFVGTGDTTYEGPELDEEDVAVILYTSGTTGKPKGAMLTHKNLYSNASDVASYLQYTADDRVVAALPMFHVFCLTVAVNAPIVNGATILMLPKFSPKEVFRICRTYEPTIFAGVPTMYNYLYLFEEASAEDVKTLRLCISGGASMPVALLQNFEKRFNVIVSEGYGLSEASPVTCFNPLDRPRKPGSIGTNIWHVENKIVNELGEEVPVGAVGELIVRGPNVMKGYYNAPEDTAATLKDGWLYTGDLAKMDEEGYFYIVDRKKDIVLVGGYNVYPREVEEVLYTHESVAEVVVIGVPDENLGEAVRAYVVLKQTNVTEEELMHYCTLHLAKYKVPKSIEFLIELPKNTTGKLLRRALREKAMQV
>NZ_CP040334.1|WP_000963381.1|5239724_5240297_-|TetR/AcrR-family-transcriptional-regulator
MAIDRKRSIIEAATKSFSAFGYKATTMDQVAKLANVGKGTIYTFFKNKEELFGEIISNLITEMKQVAESAIRSDVSFFENVHRALYSILEFRKEHQLMIKLIQEERDMGTKEVQEVMQQVDVEIVSVIQSYLKIAIEKGEISKCDPEITAFIMLRLYVSLIFDWEKNHEPLEKEKIAELFELYLLKGLSN
>NZ_CP040334.1|WP_106822854.1|5240509_5242423_-|M48-family-metalloprotease
MINTLINVYLPHFFDWLIETSLMASILVGFILCIKVLFRNKLTPRWQYMLWIVLMIRLLLPWSPDSSYSIYSLLSYSSSVSEVIPKNMPSTENIVNIESDRKVELESNSETVTKNSEPEVNASSEQQTTLSLYKIALYVWLAGVIVLAVITFITNRRLYSYIKKQPDITDEQVATVFNRCKQSMKMKKAVSLRLAGKIASPTVFSFFRPKVLLSKKHMKVLNEQQLQYVFYHELAHIKRNDVAVNWIMYSLILLNWFNPILWYAYFCMREDQELACDAYALTFIDKEEQIAYGHTIITLLEHYSYQAPSLASLSRNKRTLKRRIVMIKKFQKKSYRLSLLGIIAIVAIASLSLFNARATEGKEKQEDKVEQSKDAFQNAVDTLFGTEEKARKEWGMSNWQYENRTAFLYHAEKALTKEEFENYVQLYKEVLQIEKKGLVRLNLPENFQGDIKEVKEERLSTEDREKLKEIRNKTTPYEDKVGKYLTYTVEEVQQHVDFQIKRPTYTIKGYTQKDERVNYYLKIKPEFTIELEYTNGKGNYTISQSQVFGESKDPFSHQFVVPENIEQYELEGNQIFYATHHSDSNLQGMKMIVPAKGKNSAYQIVIINHSLENQGEAVFDKNVNKEELEKIMLSMLK
>NZ_CP040334.1|WP_000184509.1|5242425_5242827_-|BlaI/MecI/CopY-family-transcriptional-regulator
MTNQLPKISEAELEIMKVLWSSSPQTANEIIEELEDAMDWKPKTIRTLINRLVQKEAVSYHQDKGRMYAYYPLVSQDNYLQVETKSLLKRFCGAAFKPLLVNFLKEEKLSSEDINELKRILDEKTEENKRKDR
>NZ_CP040334.1|WP_064532829.1|5243056_5243911_+|hypothetical-protein
MMRALRLNIKQAFCSRISFIMMLSGFVLICIYHYYYVIRYLGNAANGPISTDLKWIGFRDNEMDVYLLLMPVIASFPFSTSYNSDKSDGFKPFVSKGISIFPYSVAKYIVTFFCGGFLYTLPFILSLLFCKLTIPDGTPTVGSGIINADGMFANLYFDAPLTYIAVYIGINFLFAGLMALLGLAASVWSQKDYMAILFPFAAASIPYVLLNTILPSIGGAPFHLYDPKQPLQGMSPYILMTQCAFFLFVSLLMYIQGVKRDRKKYKRRLQKRERCRKAFQVISD
>NZ_CP040334.1|WP_106822856.1|5243996_5244296_-|hypothetical-protein
MQARINGKLMNQLAIFFSTIVMLQFVADITGLTSNLDITYNLINTTASYITFSLAVICTLIGARRELSKYAIILLCSVVGIKAIYFAVFVILWGLAGTP
>NZ_CP040334.1|WP_157418232.1|5244422_5246789_-|endonuclease
MAVKKLLSVFLSFLLLLSFTGTLAQAEETASMSVEKAIQVFKQQGKTKGIVEGYIVGYTQSSSKYAKDPAKFDDTNVAIADSPNETNPDKIMPVQLPKGDVRTAVNVKDHPENIGKKVSLTGTLELYFSNPGLKSVTAYKFQGEGQNRVSDVVASPNGGEVAKGTAVTLTTNTEGATIYYTLDGSNPTNKSVRYNGQIVISENSVVKAIAEKEGLTSSAISTFSFIIVNNEPVRIHDIQGKSHMSSYNGKKVNNVEGVVTALDKNGFYIEDNQPDNDPATSEGIYVYKKDANVAVGDLIQVDGVVEEYVGPGYAERFETDLTTTEIKASRVAVIAKDQSLPAPIVLGENGVKIPDQIIDNDAFGLFDPNEDAIDFYESIEGMRVTMPTPKIITPQKNGNLYVTVKNGGDKVVTQYGTPLLDENQLNPERLSVKVPRDYVAKVGDTFTGDITGVVGYDYGSFRISPITELPAVVDGGFKQVGANIQPRLDKLTVATYNIENFSANKKETTDEKVKALAYSIKYNLKMPDIIGVEEMQDNNGSINDGTTDASLSAKRIIDAVLEIRGPKYEYVEIAPNNNQDGGAPGANIRVGFFYNPSRVKLATVPKLLDKNVVRIGDENPLFESTRKPLAAEFTFQGQNIVVVANHLNSKLGDATPFGKVQPLVLKSEDKRIQLAQEVNHFVQGIQKKNTNAPVVVLGDMNDFEFSKPLKALEGTILKDMLNTVPKENRYTYIHEGNAQVLDHILVTNNIAPHTIVDPVHLNSNIMKEHGRVSDHDPVLAQIDLKKAS
>NZ_CP040334.1|WP_106822860.1|5247030_5248383_+|DUF4026-domain-containing-protein
MEVQTETYRAAMNGTLERHFSDMIAVIPTRITIEQLKQRLETIATKVDELKIVYSDETSLIVELHMGETVIPYELHIDEANDPEEYKMYNRQDSTIVDRNFEDAAFGTEIFTRTLFVGDVLDCFFQQLQFLWNLAPDLLFVIDSSAAMKVISRSYIEYHVENELLPDIPDLYVIHSVYEDDKDGEPTQYWFHTHGLLRAGLTEIELIIPNRISSYYGIGDLFQTFANNAVENGQVPMNEPIVIAHSQQGSIHTVAVPWEKGLSYIGHKTSMDQLSSIEDEEVKLQPIDAQNTFLGGMDARDEYHQSPSVLLFKFNTSEEYIESFFKEHEEATGLMFYKTNSETARMAYNAKNTFGYFSNIFHIEQSNEDFRFLAKFGVSYEEGKSEHMWFEMQNITEDFIQGILINEPYFIKDMSEGNSYHLDFDNLTEWVIYAGDAVIKPNNLYMFIGE
>NZ_CP040334.1|WP_157418233.1|5248439_5249861_-|protoporphyrinogen-oxidase
MRKKVVIVGGGITGLTAMYNLQKNIHEKNLPIDTLLIEASGKLGGKIQTVRKDGFTIERGPDSFLARKESAARLVKELGLGDELVNNQAGQSFILVKNRLHKMPNGSMMGIPTQITPFLFSGLFSPIGKLRAGFDLLMPRSKPVSDQSLGQFFRHRLGNEVVENLIEPLLSGIYAGEIDEMSLMSTFPQMYQIEQKHRSISLGMRTLTPKEEKAEPKKGMFQTVKTGLESIVKSLEVKMHEGTIIKGTRIEKVAKQGDGYTITLSNGKEIEADAIVVATSHKVLPSMFAQYKQFRFFRNIPSTSVANVALAFQKSAIQRDINGTGFVVSRNSDYTITACTWTHKKWPHTTPEGKTLLRCYVGRAGDEAVVEQTEEELVQLVLEDLRKTMDITEDPEFTIVSRWKEAMPQYTVGHNERMKKLTTFMEKELPGIYLAGSSYAGAGLPDCINQGEEAAKRVLSHLEKVIDAELIAQ
>NZ_CP040334.1|WP_000726775.1|5249880_5250816_-|ferrochelatase
MKKKIGLLVMAYGTPYKEEDIERYYTHIRRGRKPSPEMLEDLTERYRAIGGISPLATITLEQAKKLEKRLNEVQDEVEYHMYLGLKHIEPFIEDAVKDMHNDGIQDAIALVLAPHYSTFSVKSYVGRAQEEAEKLGNLTIHGIDSWYKEPKFIQYWVDAVKGIYNGMSDAEREKAVLIVSAHSLPEKIIAMGDPYPDQLNETADYIARGAEVANYAVGWQSAGNTPDPWIGPDVQDLTRELNEKHGYTSFVYAPVGFVAEHLEVLYDNDFECKVVTDEIGAKYYRPEMPNASDAFIDCLTDVVLKKKESVL
>NZ_CP040334.1|WP_000252605.1|5250830_5251877_-|uroporphyrinogen-decarboxylase
MVRTINETFLKACRGERTDYVPAWYMRQAGRSQPEYRKIKEKYSLFEITHNPELCAYVTKLPVDQYNVDAAILYKDIMSPLPAIGVDVEIKSGIGPVIDNPIRSLQDVEKLGEINPEDDVPYILDTIRLLTTEMLDVPLIGFSGAPFTLASYMIEGGPSRNYHNTKAFMYAEPKAWFALMDKLADMVITYLKAQINAGAKAVQIFDSWVGTVNVADYRVFIKPAMERIFAEVRKMGVPMIMHGVGAAHLVNEWHDLPLDVVGLDWRLPIEEARARGVHKAVQGNMDPSFLLAPWSVIEEHVKGILDQGMKQPGYIFNLGHGVFPEVNPDTLKRLTTFIHEYSKGQLAK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP040334_2	2.34\|2696572\|18\|NZ_CP040334\|CRT	2696572-2696589	18	NZ_CP040334.1	2696806-2696823	1	0.944
NZ_CP040334_2	2.34\|2696572\|18\|NZ_CP040334\|CRT	2696572-2696589	18	NZ_CP040334.1	2696887-2696904	1	0.944

1. spacer 2.34|2696572|18|NZ_CP040334|CRT matches to position: 2696806-2696823, mismatch: 1, identity: 0.944

gccggtagcacctgtgtt	CRISPR spacer
gccagtagcacctgtgtt	Protospacer
***.**************

2. spacer 2.34|2696572|18|NZ_CP040334|CRT matches to position: 2696887-2696904, mismatch: 1, identity: 0.944

gccggtagcacctgtgtt	CRISPR spacer
gccagtagcacctgtgtt	Protospacer
***.**************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	MN101228	Klebsiella phage KPN4, complete genome	27721-27747	3	0.889
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	MN434096	Klebsiella phage JIPh_Kp127, complete genome	81954-81980	3	0.889
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	MN163280	Klebsiella phage KpGranit, complete genome	83372-83398	3	0.889
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	MN163280	Klebsiella phage KpGranit, complete genome	84575-84601	3	0.889
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	MN101228	Klebsiella phage KPN4, complete genome	27721-27747	3	0.889
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	MN434096	Klebsiella phage JIPh_Kp127, complete genome	81954-81980	3	0.889
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	MN163280	Klebsiella phage KpGranit, complete genome	83372-83398	3	0.889
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	MN163280	Klebsiella phage KpGranit, complete genome	84575-84601	3	0.889
NZ_CP040334_2	2.19\|2695933\|27\|NZ_CP040334\|CRT	2695933-2695959	27	JQ691611	Cronobacter phage CR9, complete genome	9703-9729	4	0.852
NZ_CP040334_2	2.21\|2696014\|27\|NZ_CP040334\|CRT	2696014-2696040	27	JQ691611	Cronobacter phage CR9, complete genome	9703-9729	4	0.852
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	MN163280	Klebsiella phage KpGranit, complete genome	83372-83398	4	0.852
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	MN163280	Klebsiella phage KpGranit, complete genome	84575-84601	4	0.852
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	MN434096	Klebsiella phage JIPh_Kp127, complete genome	81954-81980	4	0.852
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	MN101228	Klebsiella phage KPN4, complete genome	27721-27747	4	0.852
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	NC_041979	Escherichia coli O157 typing phage 1, complete genome	75016-75042	4	0.852
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	MH571750	Escherichia phage vB_EcoM-Ro111lw, complete genome	39743-39769	4	0.852
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	NC_012749	Enterobacteria phage WV8, complete genome	54949-54975	4	0.852
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	KU886222	Erwinia phage vB_EamM_Special G, complete genome	255614-255640	4	0.852
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	EU877232	Enterobacteria phage WV8, complete sequence	54949-54975	4	0.852
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	KP869113	Escherichia coli O157 typing phage 15, partial genome	4246-4272	4	0.852
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	KP869106	Escherichia coli O157 typing phage 8, partial genome	73800-73826	4	0.852
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	KP869109	Escherichia coli O157 typing phage 11, complete genome	52980-53006	4	0.852
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	MK524176	Escherichia phage PHB11, complete genome	39303-39329	4	0.852
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	JX560968	Escherichia phage EC6, complete genome	40417-40443	4	0.852
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	NC_028872	Escherichia phage HY02, complete genome	53562-53588	4	0.852
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	KP869110	Escherichia coli O157 typing phage 12, complete genome	61247-61273	4	0.852
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	MN434096	Klebsiella phage JIPh_Kp127, complete genome	85221-85247	4	0.852
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	MN163280	Klebsiella phage KpGranit, complete genome	81269-81295	4	0.852
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	JQ691611	Cronobacter phage CR9, complete genome	9703-9729	4	0.852
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	AP013669	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C108A-MedDCM-OCT-S25-C43, * SEQUENCING IN PROGRESS *	3952-3978	4	0.852
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	AP013411	Uncultured Mediterranean phage uvMED DNA, complete genome, group G16, isolate: uvMED-CGR-C108A-MedDCM-OCT-S29-C43	29527-29553	4	0.852
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	MT380195	Klebsiella phage KP_LZD_B01, complete genome	76466-76492	4	0.852
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	MT380195	Klebsiella phage KP_LZD_B01, complete genome	78602-78628	4	0.852
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	MT380195	Klebsiella phage KP_LZD_B01, complete genome	79814-79840	4	0.852
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	KX845404	Klebsiella phage vB_Kpn_IME260, complete genome	80971-80997	4	0.852
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	KX845404	Klebsiella phage vB_Kpn_IME260, complete genome	83107-83133	4	0.852
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	KX845404	Klebsiella phage vB_Kpn_IME260, complete genome	84319-84345	4	0.852
NZ_CP040334_2	2.27\|2696275\|27\|NZ_CP040334\|CRT	2696275-2696301	27	JQ691611	Cronobacter phage CR9, complete genome	9703-9729	4	0.852
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	MN434096	Klebsiella phage JIPh_Kp127, complete genome	85221-85247	4	0.852
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	MN163280	Klebsiella phage KpGranit, complete genome	81269-81295	4	0.852
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	JQ691611	Cronobacter phage CR9, complete genome	9703-9729	4	0.852
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	AP013669	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C108A-MedDCM-OCT-S25-C43, * SEQUENCING IN PROGRESS *	3952-3978	4	0.852
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	AP013411	Uncultured Mediterranean phage uvMED DNA, complete genome, group G16, isolate: uvMED-CGR-C108A-MedDCM-OCT-S29-C43	29527-29553	4	0.852
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	MT380195	Klebsiella phage KP_LZD_B01, complete genome	76466-76492	4	0.852
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	MT380195	Klebsiella phage KP_LZD_B01, complete genome	78602-78628	4	0.852
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	MT380195	Klebsiella phage KP_LZD_B01, complete genome	79814-79840	4	0.852
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	KX845404	Klebsiella phage vB_Kpn_IME260, complete genome	80971-80997	4	0.852
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	KX845404	Klebsiella phage vB_Kpn_IME260, complete genome	83107-83133	4	0.852
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	KX845404	Klebsiella phage vB_Kpn_IME260, complete genome	84319-84345	4	0.852
NZ_CP040334_2	2.29\|2696365\|27\|NZ_CP040334\|CRT	2696365-2696391	27	JQ691611	Cronobacter phage CR9, complete genome	9703-9729	4	0.852
NZ_CP040334_2	2.31\|2696446\|27\|NZ_CP040334\|CRT	2696446-2696472	27	JQ691611	Cronobacter phage CR9, complete genome	9703-9729	4	0.852
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	MN163280	Klebsiella phage KpGranit, complete genome	81269-81295	5	0.815
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	MN434096	Klebsiella phage JIPh_Kp127, complete genome	85221-85247	5	0.815
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	AP013411	Uncultured Mediterranean phage uvMED DNA, complete genome, group G16, isolate: uvMED-CGR-C108A-MedDCM-OCT-S29-C43	29527-29553	5	0.815
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	JQ691611	Cronobacter phage CR9, complete genome	9703-9729	5	0.815
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	AP013669	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C108A-MedDCM-OCT-S25-C43, * SEQUENCING IN PROGRESS *	3952-3978	5	0.815
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	MT380195	Klebsiella phage KP_LZD_B01, complete genome	76466-76492	5	0.815
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	MT380195	Klebsiella phage KP_LZD_B01, complete genome	78602-78628	5	0.815
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	MT380195	Klebsiella phage KP_LZD_B01, complete genome	79814-79840	5	0.815
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	MT380195	Klebsiella phage KP_LZD_B01, complete genome	79769-79795	5	0.815
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	KX845404	Klebsiella phage vB_Kpn_IME260, complete genome	80971-80997	5	0.815
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	KX845404	Klebsiella phage vB_Kpn_IME260, complete genome	83107-83133	5	0.815
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	KX845404	Klebsiella phage vB_Kpn_IME260, complete genome	84319-84345	5	0.815
NZ_CP040334_2	2.25\|2696185\|27\|NZ_CP040334\|CRT	2696185-2696211	27	KX845404	Klebsiella phage vB_Kpn_IME260, complete genome	84274-84300	5	0.815
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	MT380195	Klebsiella phage KP_LZD_B01, complete genome	79769-79795	5	0.815
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	KX845404	Klebsiella phage vB_Kpn_IME260, complete genome	84274-84300	5	0.815
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	MH571750	Escherichia phage vB_EcoM-Ro111lw, complete genome	39743-39769	5	0.815
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	NC_012749	Enterobacteria phage WV8, complete genome	54949-54975	5	0.815
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	EU877232	Enterobacteria phage WV8, complete sequence	54949-54975	5	0.815
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	KP869106	Escherichia coli O157 typing phage 8, partial genome	73800-73826	5	0.815
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	KP869109	Escherichia coli O157 typing phage 11, complete genome	52980-53006	5	0.815
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	MK524176	Escherichia phage PHB11, complete genome	39303-39329	5	0.815
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	JX560968	Escherichia phage EC6, complete genome	40417-40443	5	0.815
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	NC_028872	Escherichia phage HY02, complete genome	53562-53588	5	0.815
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	NC_041979	Escherichia coli O157 typing phage 1, complete genome	75016-75042	5	0.815
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	KP869113	Escherichia coli O157 typing phage 15, partial genome	4246-4272	5	0.815
NZ_CP040334_2	2.26\|2696230\|27\|NZ_CP040334\|CRT	2696230-2696256	27	KP869110	Escherichia coli O157 typing phage 12, complete genome	61247-61273	5	0.815
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	MT380195	Klebsiella phage KP_LZD_B01, complete genome	79769-79795	5	0.815
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	KX845404	Klebsiella phage vB_Kpn_IME260, complete genome	84274-84300	5	0.815
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	MH571750	Escherichia phage vB_EcoM-Ro111lw, complete genome	39743-39769	5	0.815
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	NC_012749	Enterobacteria phage WV8, complete genome	54949-54975	5	0.815
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	EU877232	Enterobacteria phage WV8, complete sequence	54949-54975	5	0.815
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	KP869106	Escherichia coli O157 typing phage 8, partial genome	73800-73826	5	0.815
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	KP869109	Escherichia coli O157 typing phage 11, complete genome	52980-53006	5	0.815
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	MK524176	Escherichia phage PHB11, complete genome	39303-39329	5	0.815
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	JX560968	Escherichia phage EC6, complete genome	40417-40443	5	0.815
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	NC_028872	Escherichia phage HY02, complete genome	53562-53588	5	0.815
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	NC_041979	Escherichia coli O157 typing phage 1, complete genome	75016-75042	5	0.815
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	KP869113	Escherichia coli O157 typing phage 15, partial genome	4246-4272	5	0.815
NZ_CP040334_2	2.28\|2696320\|27\|NZ_CP040334\|CRT	2696320-2696346	27	KP869110	Escherichia coli O157 typing phage 12, complete genome	61247-61273	5	0.815
NZ_CP040334_2	2.33\|2696527\|27\|NZ_CP040334\|CRT	2696527-2696553	27	MK279903	Mycobacterium phage Zetzy, complete genome	2502-2528	5	0.815
NZ_CP040334_2	2.19\|2695933\|27\|NZ_CP040334\|CRT	2695933-2695959	27	MN163280	Klebsiella phage KpGranit, complete genome	83372-83398	6	0.778
NZ_CP040334_2	2.19\|2695933\|27\|NZ_CP040334\|CRT	2695933-2695959	27	MN163280	Klebsiella phage KpGranit, complete genome	84575-84601	6	0.778
NZ_CP040334_2	2.19\|2695933\|27\|NZ_CP040334\|CRT	2695933-2695959	27	MK798142	Pantoea phage vB_PagM_AAM22, complete genome	11047-11073	6	0.778
NZ_CP040334_2	2.21\|2696014\|27\|NZ_CP040334\|CRT	2696014-2696040	27	MN163280	Klebsiella phage KpGranit, complete genome	83372-83398	6	0.778
NZ_CP040334_2	2.21\|2696014\|27\|NZ_CP040334\|CRT	2696014-2696040	27	MN163280	Klebsiella phage KpGranit, complete genome	84575-84601	6	0.778
NZ_CP040334_2	2.21\|2696014\|27\|NZ_CP040334\|CRT	2696014-2696040	27	MK798142	Pantoea phage vB_PagM_AAM22, complete genome	11047-11073	6	0.778
NZ_CP040334_2	2.27\|2696275\|27\|NZ_CP040334\|CRT	2696275-2696301	27	MN163280	Klebsiella phage KpGranit, complete genome	83372-83398	6	0.778
NZ_CP040334_2	2.27\|2696275\|27\|NZ_CP040334\|CRT	2696275-2696301	27	MN163280	Klebsiella phage KpGranit, complete genome	84575-84601	6	0.778
NZ_CP040334_2	2.27\|2696275\|27\|NZ_CP040334\|CRT	2696275-2696301	27	MK798142	Pantoea phage vB_PagM_AAM22, complete genome	11047-11073	6	0.778
NZ_CP040334_2	2.29\|2696365\|27\|NZ_CP040334\|CRT	2696365-2696391	27	MN163280	Klebsiella phage KpGranit, complete genome	83372-83398	6	0.778
NZ_CP040334_2	2.29\|2696365\|27\|NZ_CP040334\|CRT	2696365-2696391	27	MN163280	Klebsiella phage KpGranit, complete genome	84575-84601	6	0.778
NZ_CP040334_2	2.29\|2696365\|27\|NZ_CP040334\|CRT	2696365-2696391	27	MK798142	Pantoea phage vB_PagM_AAM22, complete genome	11047-11073	6	0.778
NZ_CP040334_2	2.31\|2696446\|27\|NZ_CP040334\|CRT	2696446-2696472	27	MN163280	Klebsiella phage KpGranit, complete genome	83372-83398	6	0.778
NZ_CP040334_2	2.31\|2696446\|27\|NZ_CP040334\|CRT	2696446-2696472	27	MN163280	Klebsiella phage KpGranit, complete genome	84575-84601	6	0.778
NZ_CP040334_2	2.31\|2696446\|27\|NZ_CP040334\|CRT	2696446-2696472	27	MK798142	Pantoea phage vB_PagM_AAM22, complete genome	11047-11073	6	0.778
NZ_CP040334_2	2.33\|2696527\|27\|NZ_CP040334\|CRT	2696527-2696553	27	KU682439	Stenotrophomonas phage vB_SmaS-DLP_6, complete genome	61551-61577	6	0.778
NZ_CP040334_2	2.33\|2696527\|27\|NZ_CP040334\|CRT	2696527-2696553	27	MK450433	Streptomyces phage Sebastisaurus, complete genome	15056-15082	6	0.778
NZ_CP040334_1	1.2\|1215092\|31\|NZ_CP040334\|CRISPRCasFinder	1215092-1215122	31	JX238501	Bacillus phage phiAGATE, complete genome	124565-124595	8	0.742
NZ_CP040334_2	2.15\|2695735\|36\|NZ_CP040334\|CRT	2695735-2695770	36	MN163280	Klebsiella phage KpGranit, complete genome	83363-83398	8	0.778
NZ_CP040334_2	2.15\|2695735\|36\|NZ_CP040334\|CRT	2695735-2695770	36	MN163280	Klebsiella phage KpGranit, complete genome	84566-84601	8	0.778
NZ_CP040334_2	2.16\|2695789\|36\|NZ_CP040334\|CRT	2695789-2695824	36	MN163280	Klebsiella phage KpGranit, complete genome	83363-83398	8	0.778
NZ_CP040334_2	2.16\|2695789\|36\|NZ_CP040334\|CRT	2695789-2695824	36	MN163280	Klebsiella phage KpGranit, complete genome	84566-84601	8	0.778
NZ_CP040334_2	2.15\|2695735\|36\|NZ_CP040334\|CRT	2695735-2695770	36	MN434096	Klebsiella phage JIPh_Kp127, complete genome	81945-81980	9	0.75
NZ_CP040334_2	2.15\|2695735\|36\|NZ_CP040334\|CRT	2695735-2695770	36	MN101228	Klebsiella phage KPN4, complete genome	27721-27756	9	0.75
NZ_CP040334_2	2.16\|2695789\|36\|NZ_CP040334\|CRT	2695789-2695824	36	MN434096	Klebsiella phage JIPh_Kp127, complete genome	81945-81980	9	0.75
NZ_CP040334_2	2.16\|2695789\|36\|NZ_CP040334\|CRT	2695789-2695824	36	MN101228	Klebsiella phage KPN4, complete genome	27721-27756	9	0.75
NZ_CP040334_2	2.17\|2695843\|36\|NZ_CP040334\|CRT	2695843-2695878	36	MN163280	Klebsiella phage KpGranit, complete genome	83363-83398	9	0.75
NZ_CP040334_2	2.17\|2695843\|36\|NZ_CP040334\|CRT	2695843-2695878	36	MN163280	Klebsiella phage KpGranit, complete genome	84566-84601	9	0.75

1. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to MN101228 (Klebsiella phage KPN4, complete genome) position: , mismatch: 3, identity: 0.889

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcaccagtgttaccctgagg	Protospacer
************ ********.****

2. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to MN434096 (Klebsiella phage JIPh_Kp127, complete genome) position: , mismatch: 3, identity: 0.889

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcaccagtgttaccctgagg	Protospacer
************ ********.****

3. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 3, identity: 0.889

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcacctgtgttaccctgtgg	Protospacer
*********************.** *

4. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 3, identity: 0.889

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcacctgtgttaccctgtgg	Protospacer
*********************.** *

5. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to MN101228 (Klebsiella phage KPN4, complete genome) position: , mismatch: 3, identity: 0.889

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcaccagtgttaccctgagg	Protospacer
************ ********.****

6. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to MN434096 (Klebsiella phage JIPh_Kp127, complete genome) position: , mismatch: 3, identity: 0.889

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcaccagtgttaccctgagg	Protospacer
************ ********.****

7. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 3, identity: 0.889

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcacctgtgttaccctgtgg	Protospacer
*********************.** *

8. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 3, identity: 0.889

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcacctgtgttaccctgtgg	Protospacer
*********************.** *

9. spacer 2.19|2695933|27|NZ_CP040334|CRT matches to JQ691611 (Cronobacter phage CR9, complete genome) position: , mismatch: 4, identity: 0.852

gccggtagcacctgtgttaccttgaac	CRISPR spacer
cccggtaggacctgtgttaccttgagg	Protospacer
 ******* ****************.

10. spacer 2.21|2696014|27|NZ_CP040334|CRT matches to JQ691611 (Cronobacter phage CR9, complete genome) position: , mismatch: 4, identity: 0.852

gccggtagcacctgtgttaccttgaac	CRISPR spacer
cccggtaggacctgtgttaccttgagg	Protospacer
 ******* ****************.

11. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcacctgtgttaccctgtgg	Protospacer
*********************.** .

12. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcacctgtgttaccctgtgg	Protospacer
*********************.** .

13. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to MN434096 (Klebsiella phage JIPh_Kp127, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcaccagtgttaccctgagg	Protospacer
************ ********.***.

14. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to MN101228 (Klebsiella phage KPN4, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcaccagtgttaccctgagg	Protospacer
************ ********.***.

15. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to NC_041979 (Escherichia coli O157 typing phage 1, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . ***

16. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to MH571750 (Escherichia phage vB_EcoM-Ro111lw, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtaccacctgtgttaccactaac	Protospacer
******* ************* . ***

17. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to NC_012749 (Enterobacteria phage WV8, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . ***

18. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to KU886222 (Erwinia phage vB_EamM_Special G, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcaccggtgtcacctttagc	Protospacer
************ ****.***** *.*

19. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to EU877232 (Enterobacteria phage WV8, complete sequence) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . ***

20. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to KP869113 (Escherichia coli O157 typing phage 15, partial genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . ***

21. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to KP869106 (Escherichia coli O157 typing phage 8, partial genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . ***

22. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to KP869109 (Escherichia coli O157 typing phage 11, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . ***

23. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to MK524176 (Escherichia phage PHB11, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtaccacctgtgttaccactaac	Protospacer
******* ************* . ***

24. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to JX560968 (Escherichia phage EC6, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtaccacctgtgttaccactaac	Protospacer
******* ************* . ***

25. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to NC_028872 (Escherichia phage HY02, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . ***

26. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to KP869110 (Escherichia coli O157 typing phage 12, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . ***

27. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to MN434096 (Klebsiella phage JIPh_Kp127, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtatcacctttgttaccttgtgg	Protospacer
******* ***** ********** *

28. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcaccggtgttaccctgtgg	Protospacer
************ ********.** *

29. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to JQ691611 (Cronobacter phage CR9, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
cccggtaggacctgtgttaccttgagg	Protospacer
 **.**** *****************

30. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to AP013669 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C108A-MedDCM-OCT-S25-C43, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagctcctgtattaccttgtgg	Protospacer
********* *****.******** *

31. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to AP013411 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G16, isolate: uvMED-CGR-C108A-MedDCM-OCT-S29-C43) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagctcctgtattaccttgtgg	Protospacer
********* *****.******** *

32. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to MT380195 (Klebsiella phage KP_LZD_B01, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcaccagtgttaccctgtgg	Protospacer
************ ********.** *

33. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to MT380195 (Klebsiella phage KP_LZD_B01, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcaccagtgttaccctgtgg	Protospacer
************ ********.** *

34. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to MT380195 (Klebsiella phage KP_LZD_B01, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcaccagtgttaccctgcgg	Protospacer
************ ********.** *

35. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to KX845404 (Klebsiella phage vB_Kpn_IME260, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcaccagtgttaccctgtgg	Protospacer
************ ********.** *

36. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to KX845404 (Klebsiella phage vB_Kpn_IME260, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcaccagtgttaccctgtgg	Protospacer
************ ********.** *

37. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to KX845404 (Klebsiella phage vB_Kpn_IME260, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcaccagtgttaccctgcgg	Protospacer
************ ********.** *

38. spacer 2.27|2696275|27|NZ_CP040334|CRT matches to JQ691611 (Cronobacter phage CR9, complete genome) position: , mismatch: 4, identity: 0.852

gccggtagcacctgtgttaccttgaac	CRISPR spacer
cccggtaggacctgtgttaccttgagg	Protospacer
 ******* ****************.

39. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to MN434096 (Klebsiella phage JIPh_Kp127, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtatcacctttgttaccttgtgg	Protospacer
******* ***** ********** *

40. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcaccggtgttaccctgtgg	Protospacer
************ ********.** *

41. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to JQ691611 (Cronobacter phage CR9, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
cccggtaggacctgtgttaccttgagg	Protospacer
 **.**** *****************

42. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to AP013669 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C108A-MedDCM-OCT-S25-C43, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagctcctgtattaccttgtgg	Protospacer
********* *****.******** *

43. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to AP013411 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G16, isolate: uvMED-CGR-C108A-MedDCM-OCT-S29-C43) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagctcctgtattaccttgtgg	Protospacer
********* *****.******** *

44. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to MT380195 (Klebsiella phage KP_LZD_B01, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcaccagtgttaccctgtgg	Protospacer
************ ********.** *

45. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to MT380195 (Klebsiella phage KP_LZD_B01, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcaccagtgttaccctgtgg	Protospacer
************ ********.** *

46. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to MT380195 (Klebsiella phage KP_LZD_B01, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcaccagtgttaccctgcgg	Protospacer
************ ********.** *

47. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to KX845404 (Klebsiella phage vB_Kpn_IME260, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcaccagtgttaccctgtgg	Protospacer
************ ********.** *

48. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to KX845404 (Klebsiella phage vB_Kpn_IME260, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcaccagtgttaccctgtgg	Protospacer
************ ********.** *

49. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to KX845404 (Klebsiella phage vB_Kpn_IME260, complete genome) position: , mismatch: 4, identity: 0.852

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcaccagtgttaccctgcgg	Protospacer
************ ********.** *

50. spacer 2.29|2696365|27|NZ_CP040334|CRT matches to JQ691611 (Cronobacter phage CR9, complete genome) position: , mismatch: 4, identity: 0.852

gccggtagcacctgtgttaccttgaac	CRISPR spacer
cccggtaggacctgtgttaccttgagg	Protospacer
 ******* ****************.

51. spacer 2.31|2696446|27|NZ_CP040334|CRT matches to JQ691611 (Cronobacter phage CR9, complete genome) position: , mismatch: 4, identity: 0.852

gccggtagcacctgtgttaccttgaac	CRISPR spacer
cccggtaggacctgtgttaccttgagg	Protospacer
 ******* ****************.

52. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcaccggtgttaccctgtgg	Protospacer
************ ********.** .

53. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to MN434096 (Klebsiella phage JIPh_Kp127, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtatcacctttgttaccttgtgg	Protospacer
******* ***** ********** .

54. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to AP013411 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G16, isolate: uvMED-CGR-C108A-MedDCM-OCT-S29-C43) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtagctcctgtattaccttgtgg	Protospacer
********* *****.******** .

55. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to JQ691611 (Cronobacter phage CR9, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgaac	CRISPR spacer
cccggtaggacctgtgttaccttgagg	Protospacer
 **.**** ****************.

56. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to AP013669 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C108A-MedDCM-OCT-S25-C43, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtagctcctgtattaccttgtgg	Protospacer
********* *****.******** .

57. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to MT380195 (Klebsiella phage KP_LZD_B01, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcaccagtgttaccctgtgg	Protospacer
************ ********.** .

58. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to MT380195 (Klebsiella phage KP_LZD_B01, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcaccagtgttaccctgtgg	Protospacer
************ ********.** .

59. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to MT380195 (Klebsiella phage KP_LZD_B01, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcaccagtgttaccctgcgg	Protospacer
************ ********.** .

60. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to MT380195 (Klebsiella phage KP_LZD_B01, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcccctgtgtcacctttact	Protospacer
********* *******.***** * .

61. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to KX845404 (Klebsiella phage vB_Kpn_IME260, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcaccagtgttaccctgtgg	Protospacer
************ ********.** .

62. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to KX845404 (Klebsiella phage vB_Kpn_IME260, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcaccagtgttaccctgtgg	Protospacer
************ ********.** .

63. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to KX845404 (Klebsiella phage vB_Kpn_IME260, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcaccagtgttaccctgcgg	Protospacer
************ ********.** .

64. spacer 2.25|2696185|27|NZ_CP040334|CRT matches to KX845404 (Klebsiella phage vB_Kpn_IME260, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcccctgtgtcacctttact	Protospacer
********* *******.***** * .

65. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to MT380195 (Klebsiella phage KP_LZD_B01, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcccctgtgtcacctttact	Protospacer
********* *******.***** * .

66. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to KX845404 (Klebsiella phage vB_Kpn_IME260, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcccctgtgtcacctttact	Protospacer
********* *******.***** * .

67. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to MH571750 (Escherichia phage vB_EcoM-Ro111lw, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccactaac	Protospacer
******* ************* . *.*

68. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to NC_012749 (Enterobacteria phage WV8, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . *.*

69. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to EU877232 (Enterobacteria phage WV8, complete sequence) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . *.*

70. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to KP869106 (Escherichia coli O157 typing phage 8, partial genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . *.*

71. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to KP869109 (Escherichia coli O157 typing phage 11, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . *.*

72. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to MK524176 (Escherichia phage PHB11, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccactaac	Protospacer
******* ************* . *.*

73. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to JX560968 (Escherichia phage EC6, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccactaac	Protospacer
******* ************* . *.*

74. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to NC_028872 (Escherichia phage HY02, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . *.*

75. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to NC_041979 (Escherichia coli O157 typing phage 1, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . *.*

76. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to KP869113 (Escherichia coli O157 typing phage 15, partial genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . *.*

77. spacer 2.26|2696230|27|NZ_CP040334|CRT matches to KP869110 (Escherichia coli O157 typing phage 12, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . *.*

78. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to MT380195 (Klebsiella phage KP_LZD_B01, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcccctgtgtcacctttact	Protospacer
********* *******.***** * .

79. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to KX845404 (Klebsiella phage vB_Kpn_IME260, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtagcccctgtgtcacctttact	Protospacer
********* *******.***** * .

80. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to MH571750 (Escherichia phage vB_EcoM-Ro111lw, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccactaac	Protospacer
******* ************* . *.*

81. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to NC_012749 (Enterobacteria phage WV8, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . *.*

82. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to EU877232 (Enterobacteria phage WV8, complete sequence) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . *.*

83. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to KP869106 (Escherichia coli O157 typing phage 8, partial genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . *.*

84. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to KP869109 (Escherichia coli O157 typing phage 11, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . *.*

85. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to MK524176 (Escherichia phage PHB11, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccactaac	Protospacer
******* ************* . *.*

86. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to JX560968 (Escherichia phage EC6, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccactaac	Protospacer
******* ************* . *.*

87. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to NC_028872 (Escherichia phage HY02, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . *.*

88. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to NC_041979 (Escherichia coli O157 typing phage 1, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . *.*

89. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to KP869113 (Escherichia coli O157 typing phage 15, partial genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . *.*

90. spacer 2.28|2696320|27|NZ_CP040334|CRT matches to KP869110 (Escherichia coli O157 typing phage 12, complete genome) position: , mismatch: 5, identity: 0.815

accagtagcacctgtgttaccttgagc	CRISPR spacer
accagtaccacctgtgttaccgctaac	Protospacer
******* ************* . *.*

91. spacer 2.33|2696527|27|NZ_CP040334|CRT matches to MK279903 (Mycobacterium phage Zetzy, complete genome) position: , mismatch: 5, identity: 0.815

accggtagcgcccgtgttaccttgaac	CRISPR spacer
gccggtagcgcccgtgtcacctttgtc	Protospacer
.****************.***** . *

92. spacer 2.19|2695933|27|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 6, identity: 0.778

gccggtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcacctgtgttaccctgtgg	Protospacer
.**.*****************.** .

93. spacer 2.19|2695933|27|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 6, identity: 0.778

gccggtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcacctgtgttaccctgtgg	Protospacer
.**.*****************.** .

94. spacer 2.19|2695933|27|NZ_CP040334|CRT matches to MK798142 (Pantoea phage vB_PagM_AAM22, complete genome) position: , mismatch: 6, identity: 0.778

gccggtagcacctgtgttaccttgaac	CRISPR spacer
gcctgtatcacctgtgttaccttttgg	Protospacer
*** *** ***************  .

95. spacer 2.21|2696014|27|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 6, identity: 0.778

gccggtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcacctgtgttaccctgtgg	Protospacer
.**.*****************.** .

96. spacer 2.21|2696014|27|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 6, identity: 0.778

gccggtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcacctgtgttaccctgtgg	Protospacer
.**.*****************.** .

97. spacer 2.21|2696014|27|NZ_CP040334|CRT matches to MK798142 (Pantoea phage vB_PagM_AAM22, complete genome) position: , mismatch: 6, identity: 0.778

gccggtagcacctgtgttaccttgaac	CRISPR spacer
gcctgtatcacctgtgttaccttttgg	Protospacer
*** *** ***************  .

98. spacer 2.27|2696275|27|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 6, identity: 0.778

gccggtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcacctgtgttaccctgtgg	Protospacer
.**.*****************.** .

99. spacer 2.27|2696275|27|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 6, identity: 0.778

gccggtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcacctgtgttaccctgtgg	Protospacer
.**.*****************.** .

100. spacer 2.27|2696275|27|NZ_CP040334|CRT matches to MK798142 (Pantoea phage vB_PagM_AAM22, complete genome) position: , mismatch: 6, identity: 0.778

gccggtagcacctgtgttaccttgaac	CRISPR spacer
gcctgtatcacctgtgttaccttttgg	Protospacer
*** *** ***************  .

101. spacer 2.29|2696365|27|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 6, identity: 0.778

gccggtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcacctgtgttaccctgtgg	Protospacer
.**.*****************.** .

102. spacer 2.29|2696365|27|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 6, identity: 0.778

gccggtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcacctgtgttaccctgtgg	Protospacer
.**.*****************.** .

103. spacer 2.29|2696365|27|NZ_CP040334|CRT matches to MK798142 (Pantoea phage vB_PagM_AAM22, complete genome) position: , mismatch: 6, identity: 0.778

gccggtagcacctgtgttaccttgaac	CRISPR spacer
gcctgtatcacctgtgttaccttttgg	Protospacer
*** *** ***************  .

104. spacer 2.31|2696446|27|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 6, identity: 0.778

gccggtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcacctgtgttaccctgtgg	Protospacer
.**.*****************.** .

105. spacer 2.31|2696446|27|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 6, identity: 0.778

gccggtagcacctgtgttaccttgaac	CRISPR spacer
accagtagcacctgtgttaccctgtgg	Protospacer
.**.*****************.** .

106. spacer 2.31|2696446|27|NZ_CP040334|CRT matches to MK798142 (Pantoea phage vB_PagM_AAM22, complete genome) position: , mismatch: 6, identity: 0.778

gccggtagcacctgtgttaccttgaac	CRISPR spacer
gcctgtatcacctgtgttaccttttgg	Protospacer
*** *** ***************  .

107. spacer 2.33|2696527|27|NZ_CP040334|CRT matches to KU682439 (Stenotrophomonas phage vB_SmaS-DLP_6, complete genome) position: , mismatch: 6, identity: 0.778

accggtagcgcccgtgttaccttgaac	CRISPR spacer
accggtcgcgcccgtgttaccgcgcgg	Protospacer
****** ************** .* .

108. spacer 2.33|2696527|27|NZ_CP040334|CRT matches to MK450433 (Streptomyces phage Sebastisaurus, complete genome) position: , mismatch: 6, identity: 0.778

accggtagcgcccgtgttaccttgaac	CRISPR spacer
accggtagcgcccgtgtcacccttcgg	Protospacer
*****************.***.*  .

109. spacer 1.2|1215092|31|NZ_CP040334|CRISPRCasFinder matches to JX238501 (Bacillus phage phiAGATE, complete genome) position: , mismatch: 8, identity: 0.742

atcaacaagcggttcaactagtgacaaaaaa	CRISPR spacer
agtgaagggcggtttaactagtggcaaaaaa	Protospacer
* ..* ..******.********.*******

110. spacer 2.15|2695735|36|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 8, identity: 0.778

gccggtagcaccagtagcacctgtgttaccttgagc	CRISPR spacer
accctgaggaccagtagcacctgtgttaccctgtgg	Protospacer
.**   ** *********************.** *

111. spacer 2.15|2695735|36|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 8, identity: 0.778

gccggtagcaccagtagcacctgtgttaccttgagc	CRISPR spacer
accctgaggaccagtagcacctgtgttaccctgtgg	Protospacer
.**   ** *********************.** *

112. spacer 2.16|2695789|36|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 8, identity: 0.778

gccggtagcaccagtagcacctgtgttaccttgagc	CRISPR spacer
accctgaggaccagtagcacctgtgttaccctgtgg	Protospacer
.**   ** *********************.** *

113. spacer 2.16|2695789|36|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 8, identity: 0.778

gccggtagcaccagtagcacctgtgttaccttgagc	CRISPR spacer
accctgaggaccagtagcacctgtgttaccctgtgg	Protospacer
.**   ** *********************.** *

114. spacer 2.15|2695735|36|NZ_CP040334|CRT matches to MN434096 (Klebsiella phage JIPh_Kp127, complete genome) position: , mismatch: 9, identity: 0.75

gccggtagcaccagtagcacctgtgttaccttgagc	CRISPR spacer
accttgtggaccagtagcaccagtgttaccctgagg	Protospacer
.**    * ************ ********.****

115. spacer 2.15|2695735|36|NZ_CP040334|CRT matches to MN101228 (Klebsiella phage KPN4, complete genome) position: , mismatch: 9, identity: 0.75

gccggtagcaccagtagcacctgtgttaccttgagc	CRISPR spacer
accttgggaaccagtagcaccagtgttaccctgagg	Protospacer
.**   .* ************ ********.****

116. spacer 2.16|2695789|36|NZ_CP040334|CRT matches to MN434096 (Klebsiella phage JIPh_Kp127, complete genome) position: , mismatch: 9, identity: 0.75

gccggtagcaccagtagcacctgtgttaccttgagc	CRISPR spacer
accttgtggaccagtagcaccagtgttaccctgagg	Protospacer
.**    * ************ ********.****

117. spacer 2.16|2695789|36|NZ_CP040334|CRT matches to MN101228 (Klebsiella phage KPN4, complete genome) position: , mismatch: 9, identity: 0.75

gccggtagcaccagtagcacctgtgttaccttgagc	CRISPR spacer
accttgggaaccagtagcaccagtgttaccctgagg	Protospacer
.**   .* ************ ********.****

118. spacer 2.17|2695843|36|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 9, identity: 0.75

gccggtagcaccagtagcacctgtgttaccttgaac	CRISPR spacer
accctgaggaccagtagcacctgtgttaccctgtgg	Protospacer
.**   ** *********************.** .

119. spacer 2.17|2695843|36|NZ_CP040334|CRT matches to MN163280 (Klebsiella phage KpGranit, complete genome) position: , mismatch: 9, identity: 0.75

gccggtagcaccagtagcacctgtgttaccttgaac	CRISPR spacer
accctgaggaccagtagcacctgtgttaccctgtgg	Protospacer
.**   ** *********************.** .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

645790 : 654166

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_106823297.1\|645790_646378_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	9.1e-28	37.4
WP_001262441.1\|646374_647415_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	2.1e-67	45.9
WP_000879026.1\|647520_648936_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.3e-55	35.4
WP_000055560.1\|648920_651140_-	phosphoribosylformylglycinamidine synthase II	A6N228	Microbacterium_phage	2.0e-163	41.2
WP_000666785.1\|651123_651807_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_069354789.1\|651803_652058_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_001170544.1\|652050_652770_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	4.0e-49	44.3
WP_000625682.1\|652858_654166_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.9e-21	25.3

DBSCAN-SWA_2

963380 : 1036951

Bacillus_phage(15.0%)

protease,transposase,tRNA,integrase

attL 1010214:1010229|attR 1037232:1037247

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_075718925.1\|963380_964655_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	6.3e-98	52.9
WP_075718927.1\|964982_965573_-	pyridoxal 5'-phosphate synthase glutaminase subunit PdxT	NA	NA	NA	NA
WP_000186154.1\|965591_966479_-	pyridoxal 5'-phosphate synthase lyase subunit PdxS	NA	NA	NA	NA
WP_157418263.1\|966640_967948_-	D-alanyl-D-alanine carboxypeptidase DacA	B6DZZ7	Stx2-converting_phage	2.4e-20	28.0
WP_000264089.1\|968061_969525_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	2.2e-94	41.1
WP_075718931.1\|969640_970642_+	hypothetical protein	NA	NA	NA	NA
WP_001282866.1\|975929_978401_-	DNA gyrase subunit A	G3M9Z5	Bacillus_virus	1.4e-114	36.4
WP_106823395.1\|980449_981577_-	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_000680510.1\|981589_981802_-	S4 domain-containing protein YaaA	NA	NA	NA	NA
WP_001212886.1\|981929_983075_-	DNA polymerase III subunit beta	D0R7I4	Paenibacillus_phage	2.6e-18	37.7
WP_000428028.1\|983254_984595_-	chromosomal replication initiator protein DnaA	NA	NA	NA	NA
WP_000831901.1\|985159_985294_+	50S ribosomal protein L34	NA	NA	NA	NA
WP_000726621.1\|985370_985718_+	ribonuclease P protein component	NA	NA	NA	NA
WP_000727740.1\|985770_986538_+\|integrase	YidC family membrane integrase SpoIIIJ	NA	NA	NA	NA
WP_000022795.1\|986534_987152_+	protein jag	NA	NA	NA	NA
WP_063549245.1\|987378_988755_+\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE	NA	NA	NA	NA
WP_000541052.1\|988801_990691_+\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG	NA	NA	NA	NA
WP_157417221.1\|990713_991433_+	16S rRNA (guanine(527)-N(7))-methyltransferase RsmG	NA	NA	NA	NA
WP_000799016.1\|991538_992411_+	nucleoid occlusion protein	S5VTK0	Leptospira_phage	9.1e-16	36.4
WP_025966408.1\|993347_994205_+	stage 0 sporulation protein Spo0J	I3NLC2	Bifidobacterium_phage	1.9e-18	34.4
WP_061660971.1\|994225_994822_-\|protease	spore protease YyaC	A0A0A8WIQ6	Clostridium_phage	2.8e-24	39.4
WP_000365111.1\|995081_995963_+	mechanosensitive ion channel family protein	NA	NA	NA	NA
WP_000435486.1\|995983_996181_+	DUF951 domain-containing protein	NA	NA	NA	NA
WP_000524670.1\|996296_997397_+	redox-regulated ATPase YchF	NA	NA	NA	NA
WP_001233781.1\|997588_997879_+	30S ribosomal protein S6	NA	NA	NA	NA
WP_002094213.1\|997905_998427_+	single-stranded DNA-binding protein	A0A290GHL8	Caldibacillus_phage	4.0e-51	61.8
WP_000918873.1\|998472_998706_+	30S ribosomal protein S18	NA	NA	NA	NA
WP_053563260.1\|998786_999722_+	YybS family protein	NA	NA	NA	NA
WP_000864223.1\|1001769_1002216_+	50S ribosomal protein L9	NA	NA	NA	NA
WP_001286147.1\|1002243_1003593_+	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	2.5e-121	52.3
WP_000100230.1\|1003808_1005098_+	adenylosuccinate synthase	L7Y4J5	Megavirus	9.5e-70	36.2
WP_000971865.1\|1005892_1006600_+	cell wall metabolism DNA-binding response regulator WalR	W8CYM9	Bacillus_phage	7.6e-45	42.7
WP_000755367.1\|1006603_1008445_+	cell wall metabolism sensor histidine kinase WalK	W8CYF6	Bacillus_phage	8.9e-37	35.0
WP_000061569.1\|1008441_1009758_+	hypothetical protein	NA	NA	NA	NA
WP_106823399.1\|1009738_1010581_+	hypothetical protein	NA	NA	NA	NA
1010214:1010229	attL	NA	NA	NA	NA
WP_000522837.1\|1010564_1011359_+	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	6.1e-43	35.3
WP_000008032.1\|1011422_1012598_+\|protease	serine protease	W5SAB9	Pithovirus	7.7e-10	31.9
WP_001052833.1\|1012651_1012837_+	CxxH/CxxC protein	NA	NA	NA	NA
WP_001027003.1\|1012896_1013376_+	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_157417223.1\|1013455_1015474_+	GAF domain-containing protein	NA	NA	NA	NA
WP_000713633.1\|1015694_1016573_+	radical SAM protein	NA	NA	NA	NA
WP_157417224.1\|1016610_1018428_-	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	4.9e-120	38.5
WP_000432447.1\|1018565_1019549_-	GMP reductase	G3MBI2	Bacillus_virus	3.4e-160	84.7
WP_065486016.1\|1020004_1021450_+	ATP-dependent RNA helicase DbpA	A0A1V0SBR7	Catovirus	2.2e-59	34.4
WP_106823405.1\|1021693_1022932_+	hypothetical protein	NA	NA	NA	NA
WP_090978343.1\|1023080_1023641_-	DUF1836 domain-containing protein	NA	NA	NA	NA
WP_106823408.1\|1023805_1024453_+	hemolysin III family protein	NA	NA	NA	NA
WP_157417226.1\|1024772_1024955_+	hypothetical protein	NA	NA	NA	NA
WP_098509199.1\|1026789_1027455_+\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_100910529.1\|1027572_1027710_+	SapB/AmfS family lantipeptide	NA	NA	NA	NA
WP_157417228.1\|1027778_1030382_+	protein kinase	NA	NA	NA	NA
WP_098508022.1\|1031360_1033067_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	7.1e-81	37.4
WP_000993663.1\|1033369_1033723_+	PadR family transcriptional regulator	NA	NA	NA	NA
WP_086396668.1\|1033676_1034252_+	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_098508025.1\|1034248_1034848_+	NDxxF motif lipoprotein	NA	NA	NA	NA
WP_100910527.1\|1036461_1036641_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_100910526.1\|1036666_1036951_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A2I6AZV9	Macacine_betaherpesvirus	3.1e-05	31.2
1037232:1037247	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1470158 : 1515100

Bacillus_phage(12.5%)

protease,tail,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001232991.1\|1470158_1470872_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_001180555.1\|1471015_1471201_+	hypothetical protein	NA	NA	NA	NA
WP_001002982.1\|1471214_1471466_+\|coat	spore coat protein	NA	NA	NA	NA
WP_140155622.1\|1471462_1472659_+	L-lactate dehydrogenase	NA	NA	NA	NA
WP_000666168.1\|1472681_1473695_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_000713773.1\|1473760_1474408_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_000826910.1\|1474552_1475080_+	hypothetical protein	NA	NA	NA	NA
WP_088020178.1\|1475136_1475289_+\|tail	tail length tape measure protein	A0A1B1P873	Bacillus_phage	5.4e-09	60.0
WP_088020157.1\|1475639_1476488_+	WXG100 family type VII secretion target	NA	NA	NA	NA
WP_106823635.1\|1476503_1476695_+	hypothetical protein	NA	NA	NA	NA
WP_157417358.1\|1476709_1476982_+	DUF4176 domain-containing protein	NA	NA	NA	NA
WP_145959734.1\|1477088_1477478_+	hypothetical protein	NA	NA	NA	NA
WP_000218968.1\|1478228_1478594_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	5.1e-21	48.6
WP_000026896.1\|1478635_1479019_+	glycine cleavage system protein GcvH	NA	NA	NA	NA
WP_000640870.1\|1479455_1479800_+	hypothetical protein	NA	NA	NA	NA
WP_000568174.1\|1479812_1480112_+	thioredoxin family protein	NA	NA	NA	NA
WP_106823639.1\|1480264_1480609_+	hypothetical protein	NA	NA	NA	NA
WP_000601791.1\|1481019_1482045_+	methionine ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_000359401.1\|1482037_1482703_+	ABC transporter permease	NA	NA	NA	NA
WP_000735081.1\|1482726_1483539_+	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_098276845.1\|1483612_1484419_+	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000929163.1\|1484655_1485441_+	Fe-S cluster assembly ATPase SufC	A0A2R8FG22	Brazilian_cedratvirus	7.0e-07	26.1
WP_157417360.1\|1485456_1486749_+	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
WP_001020767.1\|1486748_1487969_+	cysteine desulfurase SufS	Q2XUY6	environmental_halophage	2.3e-118	47.6
WP_000009523.1\|1487958_1488390_+	iron-sulfur cluster assembly scaffold protein SufU	A0A0K1LS29	Mycobacterium_phage	1.5e-14	37.6
WP_001118824.1\|1488438_1489836_+	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
WP_157417362.1\|1490043_1490361_+	hypothetical protein	NA	NA	NA	NA
WP_157417365.1\|1490341_1491466_+	N-6 DNA methylase	Q8V6N5	Halorubrum_phage	1.5e-07	29.7
WP_157417367.1\|1491446_1492601_+	DUF262 domain-containing protein	A0A0R6PJX3	Moraxella_phage	1.3e-20	26.6
WP_098632279.1\|1492590_1493304_+	hypothetical protein	NA	NA	NA	NA
WP_157417369.1\|1493727_1495119_+	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_000248467.1\|1495184_1495487_+	DUF1805 domain-containing protein	NA	NA	NA	NA
WP_157417372.1\|1495541_1496273_+	sporulation protein YunB	NA	NA	NA	NA
WP_000944681.1\|1496346_1497330_-	M23 family metallopeptidase	NA	NA	NA	NA
WP_000166372.1\|1497519_1498416_+	lipoyl synthase	NA	NA	NA	NA
WP_106823644.1\|1498436_1498916_-	YbaK/EbsC family protein	NA	NA	NA	NA
WP_069356413.1\|1498990_1499545_-	histidine phosphatase family protein	NA	NA	NA	NA
WP_069356412.1\|1499678_1500110_+	hypothetical protein	NA	NA	NA	NA
WP_069356411.1\|1500135_1500951_-\|protease	YhfC family intramembrane metalloprotease	NA	NA	NA	NA
WP_106823646.1\|1501051_1501786_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_000744131.1\|1501820_1502399_-	hypothetical protein	NA	NA	NA	NA
WP_000435946.1\|1502517_1502826_+	YutD family protein	NA	NA	NA	NA
WP_001174588.1\|1502871_1503369_-	hypothetical protein	NA	NA	NA	NA
WP_000392613.1\|1503742_1504009_-	DUF3055 domain-containing protein	NA	NA	NA	NA
WP_000439090.1\|1504025_1504997_-	class II fructose-bisphosphatase	NA	NA	NA	NA
WP_000274010.1\|1505144_1505585_+	DUF86 domain-containing protein	NA	NA	NA	NA
WP_000503347.1\|1505665_1506298_+	transcriptional regulator	NA	NA	NA	NA
WP_000276470.1\|1506405_1507170_+	TIGR01457 family HAD-type hydrolase	NA	NA	NA	NA
WP_069356410.1\|1507358_1507940_-	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_000575380.1\|1508496_1509312_-	HAD hydrolase family protein	NA	NA	NA	NA
WP_000241506.1\|1509308_1510421_-\|protease	cysteine protease StiP family protein	NA	NA	NA	NA
WP_069356409.1\|1510426_1511773_-	adenine/guanine phosphoribosyltransferase	NA	NA	NA	NA
WP_157417374.1\|1511717_1512821_-	citrate lyase subunit beta	NA	NA	NA	NA
WP_157417377.1\|1512983_1513463_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000665102.1\|1513486_1513978_-	phosphatidylglycerophosphatase A	G3MBC5	Bacillus_virus	4.6e-41	54.5
WP_000614218.1\|1514098_1515100_+\|coat	spore coat protein CotS	NA	NA	NA	NA

DBSCAN-SWA_4

1904507 : 1912191

uncultured_Caudovirales_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001036841.1\|1904507_1905491_+	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.2e-17	26.9
WP_053563581.1\|1905480_1906251_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	5.8e-14	29.1
WP_157417504.1\|1906283_1907048_+	class B sortase	NA	NA	NA	NA
WP_000587818.1\|1907120_1907444_-	heme oxygenase	NA	NA	NA	NA
WP_053563583.1\|1907737_1908937_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	3.6e-71	41.0
WP_001014307.1\|1908975_1909170_-	YwbE family protein	NA	NA	NA	NA
WP_000018029.1\|1909512_1910205_+	response regulator transcription factor	B5LWA6	Feldmannia_species_virus	1.4e-06	28.8
WP_071731439.1\|1910206_1911142_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.2e-21	24.7
WP_071731440.1\|1911267_1912191_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.5e-45	43.5

DBSCAN-SWA_5

3953367 : 3957648

Bacillus_phage(50.0%)

integrase

attL 3945744:3945759|attR 3958511:3958526

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3945744:3945759	attL	NA	NA	NA	NA
WP_106825075.1\|3953367_3953877_-	dUTPase	A0A1L2JY27	Aeribacillus_phage	6.7e-27	45.1
WP_076876551.1\|3953896_3954148_-	helix-turn-helix domain containing protein	A0A0K2CNP4	Brevibacillus_phage	1.6e-05	40.6
WP_106825076.1\|3954355_3954715_-	cell division protein SepF	A0A1B1P7A1	Bacillus_phage	3.2e-31	51.7
WP_106825077.1\|3954707_3954986_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A2I7SC16	Paenibacillus_phage	1.9e-12	59.3
WP_076876548.1\|3955002_3955197_-	hypothetical protein	A0A1B1P7U7	Bacillus_phage	3.4e-24	82.8
WP_106825078.1\|3955847_3956312_-	hypothetical protein	NA	NA	NA	NA
WP_157418096.1\|3956544_3957648_+\|integrase	tyrosine-type recombinase/integrase	A0A0U3U8Y8	Bacillus_phage	5.5e-143	77.8
3958511:3958526	attR	NA	NA	NA	NA

DBSCAN-SWA_6

4418557 : 4427331

Bacillus_phage(71.43%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001258527.1\|4418557_4419430_-	aminoglycoside 6-adenylyltransferase	A0A1X9I6F2	Streptococcus_phage	4.0e-64	44.4
WP_106825142.1\|4419563_4420235_-	O-methyltransferase	W8CYT3	Bacillus_phage	7.7e-63	89.8
WP_000818985.1\|4420382_4421102_-	3-ketoacyl-ACP reductase	W8CYX9	Bacillus_phage	5.9e-61	100.0
WP_053564724.1\|4421391_4422465_-	HAMP domain-containing sensor histidine kinase	W8CYF6	Bacillus_phage	6.1e-187	98.0
WP_106825144.1\|4422461_4423139_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.3e-121	97.8
WP_098033672.1\|4423179_4424940_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	8.2e-274	98.4
WP_106822319.1\|4425180_4425945_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_069355432.1\|4426044_4427331_-	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	3.8e-10	30.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP040335

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP040334

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection