CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP046266	Bacillus sp. DSL-17 chromosome, complete genome	3 crisprs	cas3,DinG,PD-DExK,DEDDh,csa3,RT,WYL	1	0	6	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046266_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046266_1

3074735-3074833

Orphan

Consensus_repeat	Method
TTTGTTAGATTTTCAAAACTTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP046266_1

>merge|NZ_CP046266|1|3074735-3074833|CRISPRCasFinder
TTTGTTAGATTTTCAAAACTTTTCTCTCTTATATAACTGTAAGGGTAATAAGTTAGTGATAATTACTTAGTTTAAATTTGTTAGATTTTCAAAAGTTTT

>NZ_CP046266|1|1|3074735-3074833|CRISPRCasFinder
TTTGTTAGATTTTCAAAACTTTT	CTCTCTTATATAACTGTAAGGGTAATAAGTTAGTGATAATTACTTAGTTTAAA
TTTGTTAGATTTTCAAAAGTTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046266.1\|WP_136354762.1\|3084043_3085030_+\|TIGR03943-family-protein	unknown	unknown	gnl\|CDD\|274870
NZ_CP046266.1\|WP_136354741.1\|3071009_3071459_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046266.1\|WP_136354753.1\|3076554_3077490_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|274042
NZ_CP046266.1\|WP_136354764.1\|3085204_3085750_+\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223508
NZ_CP046266.1\|WP_136354760.1\|3083032_3084031_+\|permease	unknown	unknown	gnl\|CDD\|223773
NZ_CP046266.1\|WP_136354738.1\|3070461_3070626_-\|sporulation-histidine-kinase-inhibitor-Sda	unknown	unknown	gnl\|CDD\|370219
NZ_CP046266.1\|WP_136354756.1\|3079695_3080145_+\|damage-inducible-protein-DinB	unknown	unknown	gnl\|CDD\|368313
NZ_CP046266.1\|WP_136354736.1\|3069686_3070130_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046266.1\|WP_136354754.1\|3079003_3079441_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319898
NZ_CP046266.1\|WP_136354766.1\|3085819_3087394_-\|benzoate-CoA-ligase-family-protein	unknown	unknown	gnl\|CDD\|341269
NZ_CP046266.1\|WP_136354747.1\|3072712_3072919_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046266.1\|WP_136354745.1\|3072011_3072710_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046266.1\|WP_136354871.1\|3077898_3078852_-\|D-2-hydroxyacid-dehydrogenase	unknown	unknown	gnl\|CDD\|240625
NZ_CP046266.1\|WP_136354739.1\|3070734_3070980_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046266.1\|WP_136354758.1\|3080247_3082392_-\|DNA-topoisomerase-III	unknown	unknown	gnl\|CDD\|236078
NZ_CP046266.1\|WP_136354749.1\|3073616_3074375_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046266.1\|WP_136354743.1\|3071448_3071964_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046266.1\|WP_136354751.1\|3076032_3076419_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375187
NZ_CP046266.1\|WP_136354734.1\|3068087_3069092_-\|DUF3231-family-protein	unknown	unknown	gnl\|CDD\|371599
NZ_CP046266.1\|WP_155443902.1\|3070304_3070445_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP046266.1\|WP_136354762.1\|3084043_3085030_+\|TIGR03943-family-protein	gnl\|CDD\|274870	TIGR03943, TIGR03943, TIGR03943 family protein. Members of this occur in gene pairs with members of pfam03773. The N-terminal region contains several predicted transmembrane helix regions while the few invariant residues (G, CxxD, and W) occur in the C-terminal region.	5.57355e-55
NZ_CP046266.1\|WP_136354738.1\|3070461_3070626_-\|sporulation-histidine-kinase-inhibitor-Sda	gnl\|CDD\|370219	pfam08970, Sda, Sporulation inhibitor A. Members of this protein family contain two antiparallel alpha helices that are linked by a highly structured inter-helix loop to form a helical hairpin; the structure is stabilized by numerous hydrophobic and electrostatic interactions. These sporulation inhibitors are antikinases that bind to the histidine kinase KinA phosphotransfer domain and act as a molecular barricade that inhibit productive interaction between the ATP binding site and the phosphorylatable KinA His residue. This results in the inhibition of sporulation (by preventing phosphorylation of spo0A).	1.4745e-05
NZ_CP046266.1\|WP_136354760.1\|3083032_3084031_+\|permease	gnl\|CDD\|223773	COG0701, COG0701, Predicted permeases [General function prediction only].	7.24356e-66
NZ_CP046266.1\|WP_136354753.1\|3076554_3077490_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|274042	TIGR02224, Tyrosine_recombinase_XerC, tyrosine recombinase XerC. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerC, one of two closely related chromosomal proteins along with XerD (TIGR02225). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and homologs of XerC on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerC, as some apparent XerC examples score in the gray zone between trusted (450) and noise (410) cutoffs, along with some XerD examples. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	8.49166e-44
NZ_CP046266.1\|WP_136354756.1\|3079695_3080145_+\|damage-inducible-protein-DinB	gnl\|CDD\|368313	pfam05163, DinB, DinB family. DNA damage-inducible (din) genes in Bacillus subtilis are coordinately regulated and together compose a global regulatory network that has been termed the SOS-like or SOB regulon. This family includes DinB from B. subtilis.	2.07205e-14
NZ_CP046266.1\|WP_136354758.1\|3080247_3082392_-\|DNA-topoisomerase-III	gnl\|CDD\|236078	PRK07726, PRK07726, DNA topoisomerase 3.	0
NZ_CP046266.1\|WP_136354754.1\|3079003_3079441_-\|VOC-family-protein	gnl\|CDD\|319898	cd06587, VOC, vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). Type I extradiol dioxygenases catalyze the incorporation of both atoms of molecular oxygen into aromatic substrates, which results in the cleavage of aromatic rings. They are key enzymes in the degradation of aromatic compounds. Type I extradiol dioxygenases include class I and class II enzymes. Class I and II enzymes show sequence similarity; the two-domain class II enzymes evolved from a class I enzyme through gene duplication. Glyoxylase I catalyzes the glutathione-dependent inactivation of toxic methylglyoxal, requiring zinc or nickel ions for activity. The antibiotic resistance proteins in this family use a variety of mechanisms to block the function of antibiotics. Bleomycin resistance protein (BLMA) sequesters bleomycin's activity by directly binding to it. Whereas, three types of fosfomycin resistance proteins employ different mechanisms to render fosfomycin inactive by modifying the fosfomycin molecule. Although the proteins in this superfamily are functionally distinct, their structures are similar. The difference among the three dimensional structures of the three types of proteins in this superfamily is interesting from an evolutionary perspective. Both glyoxalase I and BLMA show domain swapping between subunits. However, there is no domain swapping for type 1 extradiol dioxygenases.	9.08144e-14
NZ_CP046266.1\|WP_136354766.1\|3085819_3087394_-\|benzoate-CoA-ligase-family-protein	gnl\|CDD\|341269	cd05959, BCL_4HBCL, Benzoate CoA ligase (BCL) and 4-Hydroxybenzoate-Coenzyme A Ligase (4-HBA-CoA ligase). Benzoate CoA ligase and 4-hydroxybenzoate-coenzyme A ligase catalyze the first activating step for benzoate and 4-hydroxybenzoate catabolic pathways, respectively. Although these two enzymes share very high sequence homology, they have their own substrate preference. The reaction proceeds via a two-step process; the first ATP-dependent step forms the substrate-AMP intermediate, while the second step forms the acyl-CoA ester, releasing the AMP. Aromatic compounds represent the second most abundant class of organic carbon compounds after carbohydrates. Some bacteria can use benzoic acid or benzenoid compounds as the sole source of carbon and energy through degradation. Benzoate CoA ligase and 4-hydroxybenzoate-Coenzyme A ligase are key enzymes of this process.	0
NZ_CP046266.1\|WP_136354871.1\|3077898_3078852_-\|D-2-hydroxyacid-dehydrogenase	gnl\|CDD\|240625	cd05300, 2-Hacid_dh_1, Putative D-isomer specific 2-hydroxyacid dehydrogenase. 2-Hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomains but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric. Formate dehydrogenase (FDH) catalyzes the NAD+-dependent oxidation of formate ion to carbon dioxide with the concomitant reduction of NAD+ to NADH. FDHs of this family contain no metal ions or prosthetic groups. Catalysis occurs though direct transfer of the hydride ion to NAD+ without the stages of acid-base catalysis typically found in related dehydrogenases. FDHs are found in all methylotrophic microorganisms in energy production and in the stress responses of plants.	6.16375e-102
NZ_CP046266.1\|WP_136354764.1\|3085204_3085750_+\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|223508	COG0431, COG0431, Predicted flavoprotein [General function prediction only].	8.12918e-44
NZ_CP046266.1\|WP_136354734.1\|3068087_3069092_-\|DUF3231-family-protein	gnl\|CDD\|371599	pfam11553, DUF3231, Protein of unknown function (DUF3231). This bacterial family of proteins has no known function.	1.73078e-48
NZ_CP046266.1\|WP_136354751.1\|3076032_3076419_-\|hypothetical-protein	gnl\|CDD\|375187	pfam17428, DUF5412, Family of unknown function (DUF5412). This is a family of unknown function found in Bacteria. Members of this family have one or two predicted trans-membrane regions.	3.27448e-06

>NZ_CP046266.1|WP_136354749.1|3073616_3074375_-|hypothetical-protein
MTMLTEAEGKIINKVVQRKLNQVILSNNWKVAKVKGKWNGGHWKAQEVESYLMEKATVRAIRFINRPENERTTELENWLNRGMEWIVKDFYKHMKTQDVLNLGDSYTEKLSVKRASMDNKVKGNGNQDNNLTLHEMVGNDNSQKTDKVTTDNTIIELVDEVLMLLEDKVSVNKYEKFTIVLEGIAFADKWTMKDDKLVKTGSVKDNGTIHLEGLGEELGMHPSTITRLLKEIAKLLENDKKSLRKFAKTVRF
>NZ_CP046266.1|WP_136354747.1|3072712_3072919_-|hypothetical-protein
METNQLLEDTVTVLSVENEKLKRKYFFATKENHQLKQDLKKAIEEIDKLELEYRRLTKMLALYDRGRK
>NZ_CP046266.1|WP_136354745.1|3072011_3072710_-|hypothetical-protein
MNMEAQLKAMNSFINSPVGRQMKLMAEQNLKSQKSLMAQKVQELSKLKEMGNPTITLASNAGEKRFVKVDGIVSYYTVSQNGKVSDIKPVTAKTYEGLDDLSKANFNSTFKAEAMALEYGSFDQKPSMDYYNKVVVANGMDSHLFELELNRPKVEHDMDFHKVPEVYNAYDSYEDYTKGITKEMKAYQQATSIEGRQERKAKIEELETEIKSLEREVGMSSSYVQFEGGNGE
>NZ_CP046266.1|WP_136354743.1|3071448_3071964_-|hypothetical-protein
MEKRTKSKLDGLTDKQRSFAIAYAGTGVIKQASEQVGIHVKTGEKYMKNELVKAYIQELSTVNTEVMTGLQMQEELSKMILNGKDEVVNYQTGEIVKVAMPNRDKIKAIELLAKMTGNLLAPDNLHIHLTEKPKEIIDLEKRWDSINRKEVYAPSEEDLNNIFGSGEDNGE
>NZ_CP046266.1|WP_136354741.1|3071009_3071459_-|hypothetical-protein
MENSISSYRLEDDGTIIIDLHGEIWDGEEEISSGQMVGKFKYAELLAVNKVYHRMKKKENLAYGLHSNHYQTMKLPKESNWVKAIEKYPIGKVIQLRKVKFEIFKVEVNLPVEAFGKGKDITKVEDFYIDVHFRLEGTKIDPSIIQIVL
>NZ_CP046266.1|WP_136354739.1|3070734_3070980_-|hypothetical-protein
MFIDSFEGLQNRKLYFITDANGTVHLLDNIVSRAWLKKNHPLHVQQTSFISKYMQSHTRIIDCTGLGLTGNEENNLTLEDF
>NZ_CP046266.1|WP_136354738.1|3070461_3070626_-|sporulation-histidine-kinase-inhibitor-Sda
MSYSWFYVEDELLINIYRKSVEQNLDKEFIEFVFTEIKGRDLVSEKPVHLLRIK
>NZ_CP046266.1|WP_155443902.1|3070304_3070445_+|hypothetical-protein
MVESELLYRELKRLTDDYSKCNNPSIQKLLQSDIELLTKALLLRKS
>NZ_CP046266.1|WP_136354736.1|3069686_3070130_+|hypothetical-protein
MNSAKEKLLWSIALPGFGQFLNGKVVKGVVILFLEFLVNVQANFNEAIISSFHRDIEKAIEQVDYQWLMFYPCLYFFAMWDAFKDAGGGKEKYAFLPFVFSAYFVTVGCIYSSSFRIFGVLFGPVWLPMLFVIPGLVVGLLIKKILS
>NZ_CP046266.1|WP_136354734.1|3068087_3069092_-|DUF3231-family-protein
MEENKLKLTSSEIGTLWGEYVNGTMTDVVNRYMVSIIEDESIKAIFEDAIKTFGKQKEQIVTFMENEGFPVPIGFTESDLFKGKPRLFTDIFCLNYLHIMTLHGLLGHSTAFAVSVRKDLRDFYDSCDNDAKKMYHQTIELLLEKGNFQRDPLFYPAKNPEFITSQDFTDGFFGKGRRLTATEIISISFNLKKSIMAKTLSIAFSQVTQIKEVRKFLEDSEKTSDGQIQALAKIMHKDNLPVPKSWETEVTTSTDSPFSDKLMLYHIGFLFQAAQAYHGTGLASAMRTDLVTTFESTILQNLMVTKKWFDLMVQNKWLEQPPLAPNRKEIAKEV
>NZ_CP046266.1|WP_136354751.1|3076032_3076419_-|hypothetical-protein
MTKRLKTLLMKLIIILFVFMAGNYLLDFLFEDLCGNDIKQKIPSPNGENVAYIFERSCGATTGFSPQLSILNKDDDFQNESGNTFRSDKDFSVEWIDEKNLKVIYDKSSETCEMDKKVNGINIEYVDE
>NZ_CP046266.1|WP_136354753.1|3076554_3077490_-|tyrosine-type-recombinase/integrase
MNLSLEDYITEIEIQNYSKSTVKNKKAILIQFERWLWESFQIELEDATTRHIKRWIKHLLDESIKANTINTKLKTLNNFYKFCIKEKILKDNPLNDIELLKEEKVMIKPFSIDDIQKMIDFYCGSNYMDVRNKTILTCLFETGIRSAELSNIMLTDVFDDALLIRGKGNKQRLVPVSLHLKRQLNKYRRVREKYLKGEECPFLFVCTRAKGGGLVMKDVNSIGRMGHDAVLNVVKRSGKACGVDVKLLVHSCRRSYAQISLGHTDLYTVSRLLGHNQLATTERYIQSMEDKTVLERGRNASPLTTLRKKYS
>NZ_CP046266.1|WP_136354871.1|3077898_3078852_-|D-2-hydroxyacid-dehydrogenase
MKSTQPTILVYSPDRAKAYAECVRNHGFNHIKVAATSEEAKKHLPGTEIILGWKFPTHLLNKPSASSVSWYQSMGAGVDDLMADATIPNNITITRIVDQFGTYISEYVFTFLLYMLKDVARMKQSQRENRWDPFIPELLAGKTIGVAGLGSIGAEIVQKARAFQMNVHGLSFNGKQAHIVDRHFSPEQWVAFVKDLDYLVLTLPLTDATKHIINHDILLAMKTNATIMNVGRGALINETDLVSVMRKGHLKAAILDVFETEPLPVDHPLYTLSNVHITSHLSGPSTTDGVCSFFVNNIQRYVNDQPLQGLVNRQRGY
>NZ_CP046266.1|WP_136354754.1|3079003_3079441_-|VOC-family-protein
MSNVWSKKLPVTQFRIARPTNQLQKIIEFYRDGIGLEIIGHFEQHSGYDGVMFGLPNAAYHLEFTQYIDAEACPPPSEDHLLVFYIPDRNARDKIVHRLAAMGYPEVAPENPYWKKNGVTIEDPDGWRIVLQNAYTQNGGETNKM
>NZ_CP046266.1|WP_136354756.1|3079695_3080145_+|damage-inducible-protein-DinB
MQTIYKMFEHLHWANEQILAVLQNSEDKMNEEKRLFSHILLTEEVWLNRIIGLENQASLIWTELGIEECSKQINQNKQKYEQFFASLPDQHADKLITYRNSTGQEFTTSIRDILTHIALHGHYHRGQINQKLRLDGFEPVGTDFITFVR
>NZ_CP046266.1|WP_136354758.1|3080247_3082392_-|DNA-topoisomerase-III
MKLIIAEKPDQASTLCAQFQRVKKDGYFEVKPNELFPNGAFCTWAIGHLTQLSAPEAYKDEWKKWSISMLPIIPDKFKYEVTKSKAKQFNIVKQLIKNPAVNEIIHAGDAGREGELIIRNIIQLSGVKKPLKRLWISSLTPASILEGFRHLLDDEKTRNLYYEAYSRACADWLVGMNASRVYSLLLKEKGMNDVFSAGRVQTPTLALIVKREKEIDAFKPEPFWEIVATFQVNGKKYQGKWQKDHQTRVMDVELANKIAAFCKDKPAEINEIITERKEYQPPLLFNLSSLQATANKAYKFSPKKTLDIVQSLYQKGIVSYPRSDSTYVTKGEAELFPEILAKLSAFDDYKDLFPLPKSSIIDNSRYVNEKKVTDHYAIIPTEQVKDPKRLSADEQKMYDMIVRRLIAAHYDKAIFDYSTLTTLVDGRAEFITKGKQQIQEGWRKVIFQEEKEKDQLLPNVSKGDRGQVHKVETKESKTQPPKRYTEGQLITLMKTAGKYLENDELEKVLSRVEGLGTEATRAGIITMLKDRKYIDVKKNQVFATDKGKVLIEAIGDQILASPEMTAKWEQRLSEIGEGQASPSVFMELTKKLSSKIVQDAITVAPNWSFEGLEVEAIQRKSSRFKVSKKLGKCKLCDGDIVDKGEFYGCANYKTNKCTFTISKKILGKKITQANVQKLLKDGSSDQIKGFKKGEKAFDAKLEWKDGKIGFLFET
>NZ_CP046266.1|WP_136354760.1|3083032_3084031_+|permease
MNRIIRGNIIDITGILIIALALFLVSLSSGVKVSSDFPPSLLNLNTIFLSILIEALPFVLIGVLIAGMIQIFVTEEHIQRWIPKNKIMAVIMSCVVGALFPACECGIVPIVRRLVSKGVPIYAAMGFMLTGPLINPIVIASTYMAFGNDIKIAGLRMGLGFIIAIIVAMIVSMLFKGNQFKASLHLSHSHEQVKDETFMNRFWSMLTHSIDEFFDMAKYLIMGAFLAAFVQTYMPAKSLLEAGSGPVSSLLVMMGLAYVLSLCSEADAFIGASFSNLFPTPSILGFLIFGPMIDLKNTLMMLSVFRFKFVFGVLSIVASIIFITLMLLKGFI
>NZ_CP046266.1|WP_136354762.1|3084043_3085030_+|TIGR03943-family-protein
MIFNFQQAIRALILLAFTILIFHLHFTGDITKFINPKYVGLSQSASIIFLLLFFIQITRIWTNRENHHDRCHHNHDDHNCEHHHDHGNTPFTVKKLFSYLIIISPLLSGFLLPAKILDAAIAEKKGGMAILTNQKQMADAGLNNGSSENNNKTGTEERYVDDNTEENEIDENLLIHENADPNDLEQNTITKDEYEQLTQELLQNSNIVMDEAMFATYYDEISMNIDKYKGKNIELTGFVYKEAGLKQEQLVISRYLISHCVADASIIGFLTELPEASSIKEDTWIKAKGILDVTTYNGTVLPYIKITNWEKVSEPKEPYLYPLNIKVL
>NZ_CP046266.1|WP_136354764.1|3085204_3085750_+|NAD(P)H-dependent-oxidoreductase
MKIVAIVGSIRKDSYNLKLAKFIQSRYTEQFDLEILSIRELPFYDQDIENDPPQVVKDFKNKVANSDAVLWVTPEYNATIPGVLGNAIDWLSRVEKVMIGKPSWIVGASMGNLGTVKAQLHLRDILFAMGLSSPLLPGNEVYVGAVHEKFNDKGELIHEPTVQFLDKVVDNFINWFNHQNR
>NZ_CP046266.1|WP_136354766.1|3085819_3087394_-|benzoate-CoA-ligase-family-protein
MIETTLNLKGVKSHYNAASRFIEENVRNGLGNKVAIISDDKTMTYNELLTDVNKFGSALKTIGVENENRMLLITYDSPEFVVSFYGAIKVGAVPIPINTMFQPNDYEYVLNNSRAKVLLIHEDFWVKLKDQRERYIYLKHVIVISDQVVQDADVTDYKEFINRGSEELEPFYTTAEDTGFWLYSSGSTGNPKGVIHYQKNMEASFKNYAQNILKMTENDVTFSASKLFFAYGLGNAMYFPFGAGGTTVLLKDRPTPDKIYETLEKTKPTIFFGVPTLYGSMINYVEKTGKIPDLSSVRICVSAGEALPSTFIQKWRELFNLDILDGIGSTEVAHIYLSNRIGDIKPGSTGKIVPGYEARILNDQSIEVGPNETGDLLIKGESITGGYWCNIEENQRKFYGKWMHTGDKYYQDDEGYFWYAGRSDDMLKVGGIWVSPIEIESLLFQHDKVLEVAVIGKKKENNLVYPKAYIVLKDGVSPSEELSQELKDYVKTNLAPYKYPREIEFLDELPKTATGKVQRFRLRV

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP046266_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046266_2

4370866-4370942

Orphan

Consensus_repeat	Method
ATAGCTTTGATGAAGGACGTCTTCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP046266_2

>merge|NZ_CP046266|2|4370866-4370942|CRISPRCasFinder
ATAGCTTTGATGAAGGACGTCTTCCTCGATGCTCACCATACTTTTGCCCTGCATAGCTTTGATGAAGAACGTCTTCC

>NZ_CP046266|2|2|4370866-4370942|CRISPRCasFinder
ATAGCTTTGATGAAGGACGTCTTCC	TCGATGCTCACCATACTTTTGCCCTGC
ATAGCTTTGATGAAGAACGTCTTCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046266.1\|WP_136352040.1\|4361814_4362270_-\|sporulation-protein-YtfJ	unknown	unknown	gnl\|CDD\|131921
NZ_CP046266.1\|WP_136352045.1\|4366030_4367614_-\|acyl--CoA-ligase	unknown	unknown	gnl\|CDD\|341276
NZ_CP046266.1\|WP_136352051.1\|4373982_4374633_-\|forespore-capture-DNA-binding-protein-RefZ	unknown	unknown	gnl\|CDD\|224228
NZ_CP046266.1\|WP_136352048.1\|4369364_4370510_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
NZ_CP046266.1\|WP_136352058.1\|4383513_4385226_-\|acetate--CoA-ligase	unknown	unknown	gnl\|CDD\|235279
NZ_CP046266.1\|WP_136352043.1\|4363948_4364953_-\|signal-peptide-peptidase-SppA	unknown	unknown	gnl\|CDD\|132934
NZ_CP046266.1\|WP_136352055.1\|4378425_4378719_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|181104
NZ_CP046266.1\|WP_136352041.1\|4362342_4363026_-\|DUF2953-domain-containing-protein	unknown	unknown	gnl\|CDD\|378578
NZ_CP046266.1\|WP_136352057.1\|4380574_4383409_+\|penicillin-binding-protein	unknown	unknown	gnl\|CDD\|223815
NZ_CP046266.1\|WP_136352056.1\|4378895_4380155_-\|tyrosine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235645
NZ_CP046266.1\|WP_136352050.1\|4373190_4373997_+\|histidinol-phosphatase-HisJ	unknown	unknown	gnl\|CDD\|236155
NZ_CP046266.1\|WP_136352046.1\|4367870_4368074_-\|alpha/beta-type-small-acid-soluble-spore-protein	unknown	unknown	gnl\|CDD\|365990
NZ_CP046266.1\|WP_155443929.1\|4375277_4377080_-\|diguanylate-cyclase	unknown	unknown	gnl\|CDD\|143635
NZ_CP046266.1\|WP_136352049.1\|4371097_4372795_-\|septation-ring-formation-regulator-EzrA	unknown	unknown	gnl\|CDD\|179877
NZ_CP046266.1\|WP_136352052.1\|4374756_4375236_+\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|224867
NZ_CP046266.1\|WP_136352054.1\|4377433_4378036_+\|30S-ribosomal-protein-S4	unknown	unknown	gnl\|CDD\|235411
NZ_CP046266.1\|WP_136352047.1\|4368160_4369360_-\|tRNA-4-thiouridine(8)-synthase-ThiI	unknown	unknown	gnl\|CDD\|234960
NZ_CP046266.1\|WP_136352039.1\|4361074_4361575_-\|thiol-peroxidase	unknown	unknown	gnl\|CDD\|179055
NZ_CP046266.1\|WP_136352044.1\|4365116_4365917_+\|NAD-kinase	unknown	unknown	gnl\|CDD\|179584
NZ_CP046266.1\|WP_136352042.1\|4363405_4363936_-\|RDD-family-protein	unknown	unknown	gnl\|CDD\|377640

Protein	Function_ID	Function_description	E-value
NZ_CP046266.1\|WP_136352040.1\|4361814_4362270_-\|sporulation-protein-YtfJ	gnl\|CDD\|131921	TIGR02874, conserved_hypothetical_protein, sporulation protein YtfJ. Members of this protein family, exemplified by YtfJ of Bacillus subtilis, are encoded by bacterial genomes if and only if the species is capable of endospore formation. YtfJ was confirmed in spores of Bacillus subtilis; it appears to be expressed in the forespore under control of SigF (see ). [Cellular processes, Sporulation and germination].	6.98963e-65
NZ_CP046266.1\|WP_136352045.1\|4366030_4367614_-\|acyl--CoA-ligase	gnl\|CDD\|341276	cd05972, MACS_like, Medium-chain acyl-CoA synthetase (MACS or ACSM). MACS catalyzes the two-step activation of medium chain fatty acids (containing 4-12 carbons). The carboxylate substrate first reacts with ATP to form an acyl-adenylate intermediate, which then reacts with CoA to produce an acyl-CoA ester. The acyl-CoA is a key intermediate in many important biosynthetic and catabolic processes.	0
NZ_CP046266.1\|WP_136352051.1\|4373982_4374633_-\|forespore-capture-DNA-binding-protein-RefZ	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.74795e-14
NZ_CP046266.1\|WP_136352048.1\|4369364_4370510_-\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	3.65761e-177
NZ_CP046266.1\|WP_136352058.1\|4383513_4385226_-\|acetate--CoA-ligase	gnl\|CDD\|235279	PRK04319, PRK04319, acetyl-CoA synthetase; Provisional.	0
NZ_CP046266.1\|WP_136352043.1\|4363948_4364953_-\|signal-peptide-peptidase-SppA	gnl\|CDD\|132934	cd07023, S49_Sppa_N_C, Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad. Signal peptide peptidase A (SppA; Peptidase S49; Protease IV): SppA is found in all three domains of life and is involved in the cleavage of signal peptides after their removal from the precursor proteins by signal peptidases. This subfamily contains members with either a single domain (sometimes referred to as 36K type), such as sohB peptidase, protein C and archaeal signal peptide peptidase, or an amino-terminal domain in addition to the carboxyl-terminal protease domain that is conserved in all the S49 family members (sometimes referred to as 67K type), similar to E. coli and Arabidopsis thaliana SppA peptidases. Site-directed mutagenesis and sequence analysis have shown these SppAs to be serine proteases. The predicted active site serine for members in this family occurs in a transmembrane domain. Mutagenesis studies also suggest that the catalytic center comprises a Ser-Lys dyad and not the usual Ser-His-Asp catalytic triad found in the majority of serine proteases. Interestingly, the single membrane spanning E. coli SppA carries out catalysis using a Ser-Lys dyad with the serine located in the conserved carboxy-terminal protease domain and the lysine in the non-conserved amino-terminal domain.	3.42485e-101
NZ_CP046266.1\|WP_136352055.1\|4378425_4378719_+\|hypothetical-protein	gnl\|CDD\|181104	PRK07758, PRK07758, hypothetical protein; Provisional.	2.27836e-48
NZ_CP046266.1\|WP_136352041.1\|4362342_4363026_-\|DUF2953-domain-containing-protein	gnl\|CDD\|378578	pfam11167, DUF2953, Protein of unknown function (DUF2953). This family of proteins has no known function.	5.74497e-11
NZ_CP046266.1\|WP_136352057.1\|4380574_4383409_+\|penicillin-binding-protein	gnl\|CDD\|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	6.49668e-167
NZ_CP046266.1\|WP_136352056.1\|4378895_4380155_-\|tyrosine--tRNA-ligase	gnl\|CDD\|235645	PRK05912, PRK05912, tyrosyl-tRNA synthetase; Validated.	0
NZ_CP046266.1\|WP_136352050.1\|4373190_4373997_+\|histidinol-phosphatase-HisJ	gnl\|CDD\|236155	PRK08123, PRK08123, histidinol-phosphatase HisJ.	4.86267e-143
NZ_CP046266.1\|WP_136352046.1\|4367870_4368074_-\|alpha/beta-type-small-acid-soluble-spore-protein	gnl\|CDD\|365990	pfam00269, SASP, Small, acid-soluble spore proteins, alpha/beta type.	2.69052e-22
NZ_CP046266.1\|WP_155443929.1\|4375277_4377080_-\|diguanylate-cyclase	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	3.3279e-54
NZ_CP046266.1\|WP_136352049.1\|4371097_4372795_-\|septation-ring-formation-regulator-EzrA	gnl\|CDD\|179877	PRK04778, PRK04778, septation ring formation regulator EzrA; Provisional.	9.76297e-179
NZ_CP046266.1\|WP_136352052.1\|4374756_4375236_+\|GAF-domain-containing-protein	gnl\|CDD\|224867	COG1956, COG1956, GAF domain-containing protein [Signal transduction mechanisms].	6.36362e-89
NZ_CP046266.1\|WP_136352054.1\|4377433_4378036_+\|30S-ribosomal-protein-S4	gnl\|CDD\|235411	PRK05327, rpsD, 30S ribosomal protein S4; Validated.	5.55561e-132
NZ_CP046266.1\|WP_136352047.1\|4368160_4369360_-\|tRNA-4-thiouridine(8)-synthase-ThiI	gnl\|CDD\|234960	PRK01565, PRK01565, thiamine biosynthesis protein ThiI; Provisional.	0
NZ_CP046266.1\|WP_136352039.1\|4361074_4361575_-\|thiol-peroxidase	gnl\|CDD\|179055	PRK00522, tpx, thiol peroxidase.	2.98294e-100
NZ_CP046266.1\|WP_136352044.1\|4365116_4365917_+\|NAD-kinase	gnl\|CDD\|179584	PRK03501, ppnK, NAD kinase.	1.74111e-177
NZ_CP046266.1\|WP_136352042.1\|4363405_4363936_-\|RDD-family-protein	gnl\|CDD\|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	1.06527e-22

>NZ_CP046266.1|WP_136352048.1|4369364_4370510_-|cysteine-desulfurase
MLYLDNSATTKPYPEVLSTYLKVTEDYFANPSSLHKLGSEAEMLLNQSRKQVATLLGVQQGEIIFTSGGTEGNNLAIKGAALANKHKGRHIITSSIEHPSVLESFKQLEEFHGFNVTYLPVNGEGIVSLEHLEKAIRDDTILISIMHVNNEVGTIQPIAEIGQMLKNNQNILFHVDNVQGITKVPLDLKNANIDLCTISGHKFHGLNGSGVLFKRSGVDLLPLFSGGSQELQMRSGTESLAGNVALAKALRMATEKAAKRGQHLENLHKQLRVKLMNIEGVVINTPLKNAAPHIINFSVPAVKAEVLIHFLGEHDIYVSTTSACSSRSKTNSQTLLAMNKPQDIAKSAIRVSLSYESNEEMILTFIDTLSKGIEKLMKVMR
>NZ_CP046266.1|WP_136352047.1|4368160_4369360_-|tRNA-4-thiouridine(8)-synthase-ThiI
MKFDHILIRFGEISTKGRNRRKFVDRLKQNIKVVLPEYTNLEYEGTRDRLYIHLHGEDHEGIVNKLQHIFGIQSFSLAIKCESDLSKIKESALEAVKGLYKPNDTFKVTAKRANKQFPLDTNELNYQIGSHILINTEGLTVDVKNPTINVRVEVRSEATFITCFDYKGAGGLPVGSSGKGMLLLSGGIDSPVAGYLSLKRGVELEIIHFFSPPYTSERAKQKVIDLTRELTAFGGKINLHIVPFTAIQEKIQQQVPENYTMTSTRRMMLKIADKLREKKQALALITGESLGQVASQTLESMVAINDVTNTPIIRPLITMDKTEIIAISKNIGTHDISIRPYEDCCTIFTPASPKTKPKLEKVSRFESFVDFEELINDAIENIESIEVSQEQKDEFSSLF
>NZ_CP046266.1|WP_136352046.1|4367870_4368074_-|alpha/beta-type-small-acid-soluble-spore-protein
MAQNNNSNQLVVPGAQQAIDQMKYEIASEFGVNLGAETTSRANGSVGGEITKRLVSFAQQQMGGSFK
>NZ_CP046266.1|WP_136352045.1|4366030_4367614_-|acyl--CoA-ligase
MVREELLAPLNYNLVEEIEKHAKDATRIALKWENEQGERSEITYRSLLDKVNRIGNALLNQGLEVGDKVLVIIPRLIDAYAVYLGALKAGLVVIPSSEMLRTKDIQYRITHGDVKAVICYGLYTNEFKEIREYENLIKIVVNGSEADWLSLEELMTKQSTEMDIAKTKSDSMAFLSYTSGTTGNPKGVVHTHGWAFAHLKTAAKNWLSIEEKDVVWATAGPGWQKWIWSPFLSVLGSGATGLIYNGKFNPEKYLQLLDEYKVNVLCCTPTEYRIMAKVDNLENYSLSALHSAVSAGEPLNREVIETFQHYFDVKVRDGYGQTENTLLVGVMKDMEIRAGSMGKPTPGNDVIIINEEGLPCSIDEVGDIAVHKDTPALFKEYYKDHERTAKQYRGDYYITGDRAKMDKDGYFWFEGRSDDIIISSGYTIGPFEVEDALVKHPLVKECAVVASPDKVRGNIVKAYIVLKDHSKHVDREIIPLLQEYVKNQTAPYKYPREIEFIEELPKTSSGKIRRIELRQREEELKLG
>NZ_CP046266.1|WP_136352044.1|4365116_4365917_+|NAD-kinase
MSDRRNVYFYYKKEEGLLEKINSIIEFAKNHDFNVVEDPALANIIVSIGGDGAFLQAVRKTNFRSDCLYAGIGIDETISLYCDFHIDDQDKMITAITESQIEVRKYPVIEVKIDDSTTFKCLNECSIRSSIIKTFVIDVFIDALHFETFRGDGMLIATPTGSTAYNKSVNGAVVDPMIPCIQVSEIASLNNNLYRTLGSSFILSDKRKLLLKIVQDGNDYPIIGMDNEALSIRNVKQLEYTLSDQPIKTVKLKDNSYWEKVKRTFL
>NZ_CP046266.1|WP_136352043.1|4363948_4364953_-|signal-peptide-peptidase-SppA
MNGKRWGAIAIASCLFVFSIITSSTMMFIKNSEMFSDPFAANASFTEEIMEEGSPDNKILVLNINGVIQDTGEDVTSFFSSPGYHHQTFLDMIEAAGEDKNVKGVILRVNSPGGGVVESAEIHKKLIELKENSKKPLYVSMGTTAASGGYYIATPADKIFAAPDTMTGSLGVIMQSINYSKLAEEFGVKFETIKSGPYKDIFSPAREMTEDERKILQTMVNDSYNGFVNVIMEGRSLPEAEVRKLADGRIYDGRQAKENKLIDELGYFDDTVAAMKKDLGIKNAQVVEYGESLGLDSFLSMGASKVFNEEMELNNLYKMLSQPNSPRLMYLYSE
>NZ_CP046266.1|WP_136352042.1|4363405_4363936_-|RDD-family-protein
MDATFENVENSEAAYDQVEKIKSNDYNHLLAGFWIRLWAYLIDLLVVSSVNRILIYPLFELMGLNNNKSFIFSPVSIATALIFFAYFVLMTKYLNQTLGKMIFGIKVISIKEENISWGTILFREFIGRYISKTIWIGYLIVAFTPKKQALHDIFADTQVIHEKLYILKHNQVKSAE
>NZ_CP046266.1|WP_136352041.1|4362342_4363026_-|DUF2953-domain-containing-protein
MFWFIVILLFLLFLFIMIILTKITVTLDLNHSGDNDHFKIKFRAWYGLIRYTIDIPFVKVDDTGPNLIVKQKQKLGSDSEHNKGKNKEEKVTPDEVMNSLSDVKEITQHIVGLHKIVKRFLKKVKVKKLEWHSQLGIGDAAHTGLLTGAAWAIKGSVIGIISQYMKLLITPVVTITPEFNRLCSKTKLQCIIQFRIGQAMLAGIRFIKYWKGGRPKLKNNPFSFFTN
>NZ_CP046266.1|WP_136352040.1|4361814_4362270_-|sporulation-protein-YtfJ
MSDHPIQGLMKTAMENLKQMIDVNTIVGDPVETPDGSVILTVSKVGFGFAAGGSEFNATSPEEGDSQKTPKLPFGGGSGGGVSITPIAFLIVSSTGVKMLHLDESTHLYEKILEAAPQTVEKIQNMFKKNKESNSAATGNVQNQQKQDLDF
>NZ_CP046266.1|WP_136352039.1|4361074_4361575_-|thiol-peroxidase
MASVTFKNNPITLVGNEVKVGDTAPDFTVLANDMSPVTLADSKGKVRLISVVPSIDTGVCDAQTRRFNEDASKLNNVEVLTISVDLPFAQKRWCAANGLENVKTLSDYKDLSFGEAYGVHMKELRLLARAVFVVDANDKVTYVEYVSEGTNHPNYEAAIEAAKTAQ
>NZ_CP046266.1|WP_136352049.1|4371097_4372795_-|septation-ring-formation-regulator-EzrA
MEVIVGLILLLCILFGVGYIYRRRIYKDVDRLEAWKIQIMNRSIIDELSKVKELKMVGQAEELFDQWRNEWDEIITTQLPEVEELLFDAEDHSDKYRFKKARNVLGHIEKVLTTVDENIDKIIEEINELVSSEEKNKVESEEIKQQVKKVKKTLLAHSYQFGKAHGKLEEKLAEVSEVLKQFDSETEEGNYLAAREILLKVKKELEHLQVKTNDIPKLLTECNITLPNLLNELEEGYKEMVGNGYYLEHIQVEIEIDKINKQIEGYRKQLENAEIDDVAESLQAIQESIDTIYDLLEKEVESNQFVKQAKETINHKLIELSEQNIATIEETNLVKQSYQLSNTELDRQKQIEKQLSQIVKKFEHINQNLQNDHVAHSIIKDELGEIDKQISQLLDDHNEYRDMLQTLRKDELQARESLNNLKRVLLEASRAVHQSNIPGLPVDFVELIDKARIEVQKVTLKLDEIPLNMIVVNQLLEDAVQTVESLKQYADEIIEQVTLVEKVIQYGNRYRSRNSQLATKFREAEELFRNYEYRKSLEAAAAALEQIEPGSLSKIQEIINEQKLK
>NZ_CP046266.1|WP_136352050.1|4373190_4373997_+|histidinol-phosphatase-HisJ
MDKKDGHIHTPYCPHGTKDKLEAYIEQAMKEEFNCITFTEHAPLPKTFTDPTPMKDSAMKLEDIEEYIRDIEALKVKYRNKITINIGLEVDYIKDYEAETKQFLNQYGKFLDDSILSVHFLKFNQSYYCMDYDEKTFGKMIDIAGSIQNLHLSYYQEVLHSIHSNLGKYKPKRIGHITLVNKFQKLYPSPFSTEESIKGILQAIKEKGLEIDYNVAGLRKEFCGETYPSEWIAKMARQQKIPLIYGSDAHSARDVGKHYIYYERLANS
>NZ_CP046266.1|WP_136352051.1|4373982_4374633_-|forespore-capture-DNA-binding-protein-RefZ
MTQQSLRDTKQKILHAAMYLFNSKGYNGTSVREIASRANVNVAHISYYFKGKGGLLEYLISQYYEGYLEVIEKNHSQLNFGNAHNILSKMILDILNYQHENRQLSRLVYREVTLDSVLIREVMTTYLTKEKYFIKSVIDQGIQEGYYRKGIVSHMIIQLRSLLHMPYLQPQYMSEVLHIQPHEAYFVHQYYKELKFWLNTLRVENHSLDGKLLAIR
>NZ_CP046266.1|WP_136352052.1|4374756_4375236_+|GAF-domain-containing-protein
MFHVEKYNGNKVEQYQLVIKQLQALLEGENDQTANLANASALLNQFLNDINWVGFYLLKKNQLVLGPFQGLPACVRIPLGRGVCGTAAANQKTERIADVHQFPGHIACDAASNSEIVIPLVKEDQLIGVLDIDSPSKNRFDELDQTYLEEFVKVLIQYI
>NZ_CP046266.1|WP_155443929.1|4375277_4377080_-|diguanylate-cyclase
MGGQSVDSVVKSKLYELLSNQLYRYSINEIIEKLIDVLKSGLNISHAVFYTYNKQLDYLTPFNERCPIKSLPQDLHEGKLSSFGEFDYIPLFQNETIFALIELKGLDRSRFPSASLDEIVKACTFFHACISQFLLITQKGRKFEQLYLLTEKFHSLMNKDHVLAELITTLKTMYSDYLFYLFLSHDNDNQGDLPIKDLGFDDQEGNEIAMEAFVTGNVQLSFDKKNLQTLFYFPIKGKQGVYGVLQVVINHNTELDEENKGYITMLANAAGTALENAQLYEQSKRLIKDLQLINEISHRLNKNLKFTDTMTYLSSKIMDSFDAEEVGFFYINQYGMIQFFPGSTKFFSTEEINVYIEYLREKIEKDLEGLFIGDIKSYIHDATYSSVMAVPMVQSNNLKGCALVLHKEPYHFSFDMFKLLQSLIHHTTLALTNSLLREELETLVKTDHLTQLFSRSYFNERIEQSINKDRQGTFVLIDIDDFKRINDTYGHQTGDEVLVQVANIIKNNIREDDVAARWGGEEISVYLPQVDLKTGIIIAERIVKCVRENTSPVITISCGVSYWNAKNHENANKLFSRADKALYIAKNMGKNQVIIQEEVT
>NZ_CP046266.1|WP_136352054.1|4377433_4378036_+|30S-ribosomal-protein-S4
MARYTGSSWKLSRRLGISLSGTGKELEKRPYAPGQHGPGQRKKLSEYGLQLQEKQKLRHMYGVNERQFRNLFDKAGKIAGKHGENFMVLLESRLDNVVYRLGLARTRRQARQIVNHGHILVDGGRVDIPSYQVKPGQTITLREKSRNLDIVKEAIEVNNFVPDYLTFDADKLEGTFTRLPERSELPAEINEALIVEFYSR
>NZ_CP046266.1|WP_136352055.1|4378425_4378719_+|hypothetical-protein
MTTSEKNLKTCNKGHKYYKSSDCPTCPTCEQKRKPENGFLSLLSAPARRALEHNGITSLHLLSTYSEKEILKLHGMGPAFLPKLRTALKENGLSFKS
>NZ_CP046266.1|WP_136352056.1|4378895_4380155_-|tyrosine--tRNA-ligase
MSELLNDLQFRGLVNQVTDEEGLTKILEEEKIKLYAGFDPTADSLHIGHLLPILTLKRFQLHGHHPIALVGGATGLIGDPSGKKAERTLNTADIVQEWSNRIKGQLSRFLDFDAEVNPAIIANNFDWIGSLDVISFLRDVGKNFGINYMLAKDSVKTRIDSGISFTEFSYMILQSFDFLKLYQNNGCKLQIGGSDQWGNITSGLELIRKSEENSKAYGLTIPLVTKADGTKFGKTEGGAIWLDRDKTSPYEFYQFWINTDDRDVIKYLKYFTFLSQQEIEQFEQEVSSAPEKRLAQKALAEEMTKLVHGEESLQQAIKITAALFSGDIKELTGNEILEGFKDVPSTKIEEAEIGLIDLLIQAKIAPSKRQAREDITNGAIYINGERVQDLEKVIANQDKIDGQFTVIRRGKKKYFLIRF
>NZ_CP046266.1|WP_136352057.1|4380574_4383409_+|penicillin-binding-protein
MKKKEEKLRRFSPFNKDIIRGFRISYSVIGSLLLLFFIIGLIGLCFAGGVGAGYFASLVKDEPIRSYNVMKNDIYNYEETSQVFFANNVLLGKINADIEREEVKLEDVSQHVIHAVIATEDELFYEHDGVVPKAIMRALFQEFTNAAVKTGGSTLTQQLIKNQILTNEVSFDRKAKEILLALRLEKFFEKDEIIEAYLNVTDFGRNSNGRNIAGVQAAAKGIFGVEAKDLNIPQSAFIAGLPQSPFGYTPFSNKGGAVKENLDPGINRMKTVLKRMYSGGYITEEEYKAALTYDIRANLTDKKPSSIDQYPYLTYEIEDRAKQIIMLQLATEDGYTEDELDKDDVLYNQYRALADNEIRHNGYRIHTTIHKDIYDKMQDVVAQYEYYGSDKPEQIKDPDTGETITIQEPVEAGGVLIENSTGKIISFVGGRDFERENLNHATNAVRQNGSTMKPLLVYAPALELGLVQPGSVIADVPYTINGYSPKNSGGSYHGLTSARTALKYSYNIPAVKTFMSVINKNPASYLEKMGISQIPDSLYPSHSLGSSGVTVEENVNAFATFANKGKFVDAYMIEKIENSDGKVIYQHEKTATDVFSAQTAYLTIDMMRDVIRGGTAASLNGFLSFSADWSGKTGTTQDYGDAWFVATNPNVTFGTWIGYDTPKPLERNYKGMSYSKRNILLWAKLMNVSHDVNPELIAPKERFEMPGGIVERSYCALTGELPSDLCRSAGLVTSDLFNAKYVPTKVDDSLTHGKFVVVKNQAYKVPSSAPSEFVQQGVMLKKDILKKHGISSIGDLKKLLPNTAKFGNLVVTENKEISDNGASPKQVSGVSVNGPKISWGANPDNDVIGYRVYAAANQTTNFKKVASVHASSTSANVGTAPAAYYVVAVDVAGKESAPSAIIKVGNYAKEKSKPVATETVKPKTPPAAPAKPAKPAVTPPSEAI
>NZ_CP046266.1|WP_136352058.1|4383513_4385226_-|acetate--CoA-ligase
MKLEALSPTKGNFNLQDYDAVYESFDWSEVEKNFTWSETGRVNAAYEAIDKHAESFRKNKIALYYRDPERDEKYTFKEMKELSNKAANVLKKTADLEKGDRLFVFMPRTPELYFVLLGAIKLGAIVGPLFEAFMEGAVKDRLEDSDAKVIVTTPELLDRIPVSELPALKHVVVVGESVDSKYIDFLAEMKTASKELNIEWVEKTDGLLLHYTSGSTGKPKGVLHVHQAMVQHYQTGQWVLDLQEDDVYWCTADPGWVTGTVYGIFSPWLSGATNVIVGGRFKPEAWYKTIEDYGVTVWYSAPTAFRMLMSAGDELVKQFDTSSLRHVLSVGEPLNPEVVRWGVKVFHKRIHDTWWMTETGAQLICNYPCMEIRPGSMGKPIPGVKAAIVDDQGNELPPYRMGNLAIKKGWPSMMYTIWNNKEKFESYFMPGDWYVSGDSAYMDEDGYFWFQGRIDDVIMTSGERVGPFEVESKLVEHPAIAEAGVIGKPDPVRGEIIKAFVALREGYEPSDELKEEIRTFVKKGLAAHAAPREIDFRDKLPKTRSGKIMRRVLKAWELDLPTGDLSTMED

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP046266_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046266_3

4809136-4809476

Orphan

Consensus_repeat	Method
TCATTNCCTTGATGAAGGACCTTTTCCACTTA	CRT

6 spacers

The CRISPR arrays of NZ_CP046266_3

>merge|NZ_CP046266|3|4809136-4809476|CRT
TCATTACATCGATGAAGGACGATTTTTACTTAAATTTCATTAGAACTGTCCTTCATTTCCTTGATGAAGGACCTTTTCCACTTATTTTGCATCAGATCAGTCCTTCATTTCCTTGATGAAGGACCTTTTCCACTTATTTCGCATCAAAACCGTCCTTCATTTCCTTAATGAAGGACCTTTTCCACTTACATCACAGCAAAAAGACCTTCATACCTTGATGAAAGACCTTTTCCAATTATTTCGCATCTGAAAAGTCCTTCATTTCCTTGATGAAGGACCTTTTCCACTTACATCACAGCAGAAAAGTCCTTCATACCTTGATGAAGGACTTTTCTCTAATT

>NZ_CP046266|3|1|4809136-4809476|CRT
TCATTACATCGATGAAGGACGATTTTTACTTA	AATTTCATTAGAACTGTCCT
TCATTTCCTTGATGAAGGACCTTTTCCACTTA	TTTTGCATCAGATCAGTCCT
TCATTTCCTTGATGAAGGACCTTTTCCACTTA	TTTCGCATCAAAACCGTCCT
TCATTTCCTTAATGAAGGACCTTTTCCACTTA	CATCACAGCAAAAAGACC
TTCATACCTTGATGAAAGACCTTTTCCAATTA	TTTCGCATCTGAAAAGTCCT
TCATTTCCTTGATGAAGGACCTTTTCCACTTA	CATCACAGCAGAAAAGTCC
TTCATACCTTGATGAAGGACTTTTCTCTAATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046266.1\|WP_136352541.1\|4815222_4816020_-\|DUF2935-domain-containing-protein	unknown	unknown	gnl\|CDD\|378573
NZ_CP046266.1\|WP_046512441.1\|4811654_4811825_-\|twin-arginine-translocase-TatA/TatE-family-subunit	unknown	unknown	gnl\|CDD\|237837
NZ_CP046266.1\|WP_136352545.1\|4813294_4813882_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP046266.1\|WP_136352540.1\|4816210_4816315_-\|YjcZ-family-sporulation-protein	unknown	unknown	unknown
NZ_CP046266.1\|WP_136352546.1\|4809758_4811609_-\|M3-family-oligoendopeptidase	unknown	unknown	gnl\|CDD\|341070
NZ_CP046266.1\|WP_136352555.1\|4801950_4802232_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046266.1\|WP_136352549.1\|4806062_4807067_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NZ_CP046266.1\|WP_136352542.1\|4814692_4815007_+\|EamA-family-transporter	unknown	unknown	unknown
NZ_CP046266.1\|WP_136352547.1\|4808377_4809103_+\|ZIP-family-metal-transporter	unknown	unknown	gnl\|CDD\|223505
NZ_CP046266.1\|WP_136352556.1\|4800826_4801744_-\|proline-dehydrogenase	unknown	unknown	gnl\|CDD\|223580
NZ_CP046266.1\|WP_136352551.1\|4803844_4804663_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224045
NZ_CP046266.1\|WP_136352552.1\|4803108_4803852_-\|iron-reductase	unknown	unknown	gnl\|CDD\|226599
NZ_CP046266.1\|WP_136352543.1\|4814266_4814584_+\|multidrug-efflux-SMR-transporter	unknown	unknown	gnl\|CDD\|224987
NZ_CP046266.1\|WP_136352550.1\|4805010_4806066_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NZ_CP046266.1\|WP_136352553.1\|4802823_4803081_-\|YusU-family-protein	unknown	unknown	gnl\|CDD\|313925
NZ_CP046266.1\|WP_136352750.1\|4811926_4813045_-\|D-alanyl-D-alanine-carboxypeptidase	unknown	unknown	gnl\|CDD\|224600
NZ_CP046266.1\|WP_136352539.1\|4816545_4816728_-\|DUF4025-domain-containing-protein	unknown	unknown	gnl\|CDD\|315803
NZ_CP046266.1\|WP_136352548.1\|4807234_4808239_+\|iron-siderophore-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238566
NZ_CP046266.1\|WP_136352544.1\|4813921_4814263_+\|multidrug-efflux-SMR-transporter	unknown	unknown	gnl\|CDD\|224987
NZ_CP046266.1\|WP_136352554.1\|4802243_4802585_+\|spore-coat-protein	unknown	unknown	gnl\|CDD\|377935

Protein	Function_ID	Function_description	E-value
NZ_CP046266.1\|WP_136352541.1\|4815222_4816020_-\|DUF2935-domain-containing-protein	gnl\|CDD\|378573	pfam11155, DUF2935, Domain of unknown function (DUF2935). This family of proteins with unknown function appears to be restricted to Firmicutes. The structure of this protein has been solved and each domain is composed of four alpha helices. A metal cluster composed of iron and magnesium lies between the two domains.	1.29007e-37
NZ_CP046266.1\|WP_046512441.1\|4811654_4811825_-\|twin-arginine-translocase-TatA/TatE-family-subunit	gnl\|CDD\|237837	PRK14861, tatA, twin arginine translocase protein A; Provisional.	3.57434e-24
NZ_CP046266.1\|WP_136352545.1\|4813294_4813882_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	4.54885e-13
NZ_CP046266.1\|WP_136352546.1\|4809758_4811609_-\|M3-family-oligoendopeptidase	gnl\|CDD\|341070	cd09607, M3B_PepF, Peptidase family M3B, oligopeptidase F (PepF). Peptidase family M3B Oligopeptidase F (PepF; Pz-peptidase B; EC 3.4.24.-) is mostly bacterial and is similar to oligoendopeptidase F from Lactococcus lactis. This enzyme hydrolyzes peptides containing between 7 and 17 amino acids with fairly broad specificity. The PepF gene is duplicated in L. lactis on the plasmid that bears it, while a shortened second copy is found in Bacillus subtilis. Most bacterial PepFs are cytoplasmic endopeptidases; however, the Bacillus amyloliquefaciens PepF oligopeptidase is a secreted protein and may facilitate the process of sporulation. Specifically, the yjbG gene encoding the homolog of the PepF1 and PepF2 oligoendopeptidases of Lactococcus lactis has been identified in Bacillus subtilis as an inhibitor of sporulation initiation when over-expressed from a multicopy plasmid.	0
NZ_CP046266.1\|WP_136352549.1\|4806062_4807067_-\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	5.63279e-87
NZ_CP046266.1\|WP_136352547.1\|4808377_4809103_+\|ZIP-family-metal-transporter	gnl\|CDD\|223505	COG0428, COG0428, Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism].	1.23669e-16
NZ_CP046266.1\|WP_136352556.1\|4800826_4801744_-\|proline-dehydrogenase	gnl\|CDD\|223580	COG0506, PutA, Proline dehydrogenase [Amino acid transport and metabolism].	5.94667e-75
NZ_CP046266.1\|WP_136352551.1\|4803844_4804663_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	7.33685e-133
NZ_CP046266.1\|WP_136352552.1\|4803108_4803852_-\|iron-reductase	gnl\|CDD\|226599	COG4114, FhuF, Uncharacterized Fe-S protein [General function prediction only].	7.98635e-16
NZ_CP046266.1\|WP_136352543.1\|4814266_4814584_+\|multidrug-efflux-SMR-transporter	gnl\|CDD\|224987	COG2076, EmrE, Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism].	1.02778e-23
NZ_CP046266.1\|WP_136352550.1\|4805010_4806066_-\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	1.18891e-83
NZ_CP046266.1\|WP_136352553.1\|4802823_4803081_-\|YusU-family-protein	gnl\|CDD\|313925	pfam10835, DUF2573, Protein of unknown function (DUF2573). Some members in this bacterial family of proteins are annotated as YusU however no function is currently known. This family of proteins appears to be restricted to Bacillus spp.	1.30776e-34
NZ_CP046266.1\|WP_136352750.1\|4811926_4813045_-\|D-alanyl-D-alanine-carboxypeptidase	gnl\|CDD\|224600	COG1686, DacC, D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane].	7.85742e-89
NZ_CP046266.1\|WP_136352539.1\|4816545_4816728_-\|DUF4025-domain-containing-protein	gnl\|CDD\|315803	pfam13217, DUF4025, Protein of unknown function (DUF4025). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 60 amino acids in length. There is a conserved EGT sequence motif.	2.22003e-12
NZ_CP046266.1\|WP_136352548.1\|4807234_4808239_+\|iron-siderophore-ABC-transporter-substrate-binding-protein	gnl\|CDD\|238566	cd01146, FhuD, Fe3+-siderophore binding domain FhuD. These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA-like protein is comprised of two globular subdomains connected by a long alpha helix and binds its specific ligands in the cleft between these domains.	3.73529e-88
NZ_CP046266.1\|WP_136352544.1\|4813921_4814263_+\|multidrug-efflux-SMR-transporter	gnl\|CDD\|224987	COG2076, EmrE, Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism].	2.01565e-22
NZ_CP046266.1\|WP_136352554.1\|4802243_4802585_+\|spore-coat-protein	gnl\|CDD\|377935	pfam07875, Coat_F, Coat F domain. The Coat F proteins, which contribute to the Bacillales spore coat. It occurs multiple times in the genomes it is found in.	4.19398e-20

>NZ_CP046266.1|WP_136352547.1|4808377_4809103_+|ZIP-family-metal-transporter
MLQSAFWGALAGSSILIGALIGLYTDLPKKVTGLIMSFGTGVLIGAASFELLTESIREDGVLTTSIGFLSGAFVFTISELFITKKGGNERKRTKKRSDNHSGLSIFIGTIIDAIPESVIIGVSLLEQGTVSYLMVIAVFLSNFPEGLSSTVGLKKDGYSKKTLLIMWLIVVLLASLSSLLGFSLLQDASTTLLSFISAFAAGGIMAMVASTMMPEAFEEGGAIVGLISSFGLLCSLILSQF
>NZ_CP046266.1|WP_136352548.1|4807234_4808239_+|iron-siderophore-ABC-transporter-substrate-binding-protein
MQTTYKKSWLSLFLLSIIMLVLAACGNKAEEGTETEGAEGNNDSKAEETYTIEHAMGTTEITGTPKKVVILTNEGTEALLSLGVKPVGAVQSWLGEPWYEHIASDMKDVEVVGTESEINIEAIAALKPDLIIGNKMRQEKSYEQLKAIAPTVFSETLRGDWQENFKLYAKALNLEEDGQKVIDDFEARITEFKETAGDKLNQEVSVVRFMAGLTRVYYTDTFSGVIFDKLGLKHSSSVQELFADNKDDLFVREVGKEVIPKMDADILFYFTYAPPGDTEATKTEEEWTNDPLWKNLEVVKAGKAYKVDDAIWNTAGGVLAANKLLDDLEEIIMK
>NZ_CP046266.1|WP_136352549.1|4806062_4807067_-|iron-ABC-transporter-permease
MVLKSNQLKIFGLIIGIILLIVLMFGSLILGYTDTSWKLAYEAFTSFDGSNEHIIIQNVRLPRSLIGAVVGACLAVAGALMQALTKNPLASPDVFGISAGAGFFLVIGVSIFYVDSLQAFTWIAFAGAAFTAFVVYFIGSFGREGLTPMKLTLAGAAMAGLFASLTQGLLVVNESALDQVLFWLAGSVQGRKLESLHTILPYVIPALIISMIMAQKINVLTMGEAVAKGLGQRTGFVKILAALIIIVLGGGAVAVAGPISFIGIVIPHFARFLVGHDHRWIIPYSAVLGGALLVIADILARFIIMPEEVPVGVMTALIGTPVFVYIARRGFGQK
>NZ_CP046266.1|WP_136352550.1|4805010_4806066_-|iron-ABC-transporter-permease
MKKYFRLRLGSDKISFLIDKKALITSLILLVIVLTIFIFSTSIGEVIISPLNVVKTFFGYGNEMENLFVYSFRLPRIIIALLVGICLAVAGAILQGLIRNPLASPDIIGITGGGSVAVVVFLMLFSNKNNALTVSIEWMPVAAFIGTTIIGLLVYLLSWKNGSSSIRLVLIGIGLSMLTQSLTTLFMIKGPIYQAAQANVWITGTVYASTWEHVRVLLPVVIILLLVSLISVRRVNIQELGDELATGVGSAVQKNRLFLLILSTALTGSAVAFAGAIGFVGLMAPHIARRLVGSSFGALLPVSALIGAILVMVADLIGRTLFSPLEVPAGVFTAAIGAPYFIYLLYKSRNN
>NZ_CP046266.1|WP_136352551.1|4803844_4804663_-|ABC-transporter-ATP-binding-protein
MHAIETDALTLSYGDTIIINELNVKIPKGEITVFIGSNGCGKSTLLRSIARLLKPKEGTVLLEGSSIAKLPTKEVAKQLAILPQGPVAPEGLTVLQLVKQGRYPYQSWLKQWTEEDEAAVNSALEATGMQDFAERAVDSLSGGQRQRAWIAMTLAQKTDIILLDEPTTYLDLTHQIEILDLLFELNERENRTIVMVLHDLNLACRYAHNLVALKDQKIFAQGRPEDVITCSLVQNVFQMNCDVTVDPLFGTPLCIPHGKGRCIVKEVGVMNG
>NZ_CP046266.1|WP_136352552.1|4803108_4803852_-|iron-reductase
MAELTKTEINSLSKYRLSTEHSVKDHTFYGSDLLNPVKLKELFEGSLQHKLNTNNQHVIGSMLVKRYAFLAALVLNAMSLFNKGINCSLHNMFMQTDEKDPLWLPNFYFEDKEVTTPEMNRAQWRTSVVQTLFLENIEKVITTISKQAKVSKVILWENIAIYIFWMYETVLQDPNLSDEVAAIVQEDFHYVVMEAPPLLFGTKARNPLTQFYQPKQNDIRMRKTCCLFYLTSKNHDRCQTCPIECKK
>NZ_CP046266.1|WP_136352553.1|4802823_4803081_-|YusU-family-protein
MENEFRKQFDGLLEKYTELLVGDDSEEVIEKVKIWALYSHISKSMPPLAKHWNATYPDAKNEIKEMISEIKQLNEKHRQITKKEE
>NZ_CP046266.1|WP_136352554.1|4802243_4802585_+|spore-coat-protein
MNNNQPQKIANPETQIQKGPQMNDRDFVNDLLATEKYMTDSYSTALNEASHQALYQDILTIFNETQQAERDLYNYMFQNGWYSLEAAETQKLQQSYQQFSNYLQQQSPYGMTQ
>NZ_CP046266.1|WP_136352555.1|4801950_4802232_+|hypothetical-protein
MQQQNMQQQQTMMQQPPSIVTTKDQLYLTDMLSWNLLAMKKAHFFASQCQNQDVKNQLEKVGQMHHQHYQRILSHLQTQQQQQQQQATGSQLQ
>NZ_CP046266.1|WP_136352556.1|4800826_4801744_-|proline-dehydrogenase
MEKLLRNSFMYLSKNKMLTKLAKKYGLRFGASRFVAGDTIERATKVIKDLNKQGLVVTLDFLGEFIEDEQEAYEMATNSIKAIEAIGNNDLQSQLSLKLTSMGLDISDEVVMKNMRRIMTVAKQQNVFVTIDMEDYSRCQRTIDIFKELKKEFNNIGTVLQAYLYRTVKDIEELNEFSPNLRLVKGAYKESPKVAFPEKKDVDENYKKIIKMHLLNGNFTAVATHDDAMIDYTKKLVKEHHIPKDQFEFQMLYGIRPEKQLELVKEGYSMRVYVPYGTDWYGYFMRRLAERPANVAFVLKGIMKR
>NZ_CP046266.1|WP_136352546.1|4809758_4811609_-|M3-family-oligoendopeptidase
MSLFLCDKNKKRIGGVKLNTPIFKETWDLETFFNGGSHSSEFKTYLQEIDQLVNDLEQDMRKWPGTFSQNDINILLMSIKKISFITIKLEQANSFVGCLQAQDTSDGQANLLRSKLTSMSSAFTKVMLTFEQLLGDIEEDVWAALLKDSQLIEITYVLNEMRNRTKERLSVEKEQLIQDLSVDGYFGWEQLYDLLVAKIQIPFEENNEIKHLSVGQASNKFSDHDRNVRKSLFEKWETAWGSQADVFAETLNRLAGFRLKVYKERGWDDPLKEPLEINRMKKETLETMWQVISENKQPLVDYMKRKAKMLGVPKLSWYDVEAPVGEASSAMTYQEGAQFILKQFEQFGPLLTKFTKTAFEQQWIEAEDRPGKAPGGFCTSFPESDQSRIFMTFSGTPSNVSTLAHELGHAFHSYAMKDVHPLNCDYAMNVAETASTFAEMIVADAAVKQAKDKTERLALLEDKLQRSVALLMNIHARFLFETAFYEERKLGVVPSERLSELMVKAQKEAYCDSLEEYHPHFWASKLHFFITDVPFYNFPYTFGYLFSLGIYAKALEEGKAFEKKYIDLLKDTGAMTVEELAAKHLSVDLTKRDFWENAVAIAVSDVEDFMKLTNES
>NZ_CP046266.1|WP_046512441.1|4811654_4811825_-|twin-arginine-translocase-TatA/TatE-family-subunit
MNLGFGEIMLIVFVALLLFGPKKLPELGKAAGKTLREFKRATKGLMDDEDDTSVKK
>NZ_CP046266.1|WP_136352750.1|4811926_4813045_-|D-alanyl-D-alanine-carboxypeptidase
MISATSENNELQLNSEAVILIDAQSGQVLYEKNSDEKLPPASITKIATAIYAIEKGNLNDIVSISENATKAEGTLVYLEAGEQVPLKKLIQGLLINSGNDAGVAIAEHLSGTVEQFVIDFNQYLQEEIGVEDTHFTNPHGLYNPEHLTTAEDMAKITQYAIQNELFREIFDTQELKWDGETWDTTLINHHLMVRDQSYEGITGGKNGFVTEAGFTLVTSAEREKLSLIAVTLNSKTDEQSYQDTTALFNYGFQHFETEKIESNEQFVDAWKNKYETDEEIVYVKKIGETVEKDILPTGELLIKGEDDRTIKQEMLEELKSNDKNEQLKSKIVEPPVSEEQINAEKHLHILVPFAIFISFCISGIFYLQIRKI
>NZ_CP046266.1|WP_136352545.1|4813294_4813882_+|TetR/AcrR-family-transcriptional-regulator
MMKMSSNEIKKAGLFHFANSGYDGTSLSAIAGEVGIKKQSIYAHFANKDELFLTILNEVLATERTYIQDFFTKDHLNLKVALFEFLQGFSKRYEMYDNTKFLLRMGFLPPTHLYQQVMDKVYLFYDDIEKVLIDVFEQNRDSLTEPVNDVVTAFIGLYDTVLVELLYSGNDRFQKRLHASWKIFWKGITLHAEAP
>NZ_CP046266.1|WP_136352544.1|4813921_4814263_+|multidrug-efflux-SMR-transporter
MNKHWVIVYFAAIFEVSWVTGLKHAGSSFEWAGTILAIMISFYLLIKATNHLPISTVYAVFTGLGAAGTVLVEILFFSTSISLLKIGLCTLLISGVIGLKLVTNDRNTSKREV
>NZ_CP046266.1|WP_136352543.1|4814266_4814584_+|multidrug-efflux-SMR-transporter
MAWVYLILAGFCEVAGVAAISKFNKKKSILNMFYLIAGFTLSFSLLSQAMESISMGTAYAVWTGIGTVGSALIGILFLGESASFKRIFFITVIITSTIGLKFIPH
>NZ_CP046266.1|WP_136352542.1|4814692_4815007_+|EamA-family-transporter
MTLGDMLFLLIFLSPNFIVNGSLGEGLWKFGSILGFFGVLLPVLLFSIGTLKIGPGLATLLGAAELPAAIIASIVVLHESVSCTKVFGVLLILFGSAVPHNSYY
>NZ_CP046266.1|WP_136352541.1|4815222_4816020_-|DUF2935-domain-containing-protein
MNTFEEAASFEHQFWLQVLGDHARFILDSLAESQKADIEKAKYFRQVFDTLLKKAREKTDLVSLTLEAEEYALEFREFKLSIIRRHVAGHIKIHLTPTFINHMVNELEEYLLVLTYLKKKEKPPIFHELHHHLVWLIDAAGHAGAISDTLDASEKQLKLKSDLFTKQFEDFYLKAVELSGYLRANIDSFPALTRMNKEVKLEIELFRGFLSEIEEMGLTKQMLSTFSPLMADHMLREECYYLMKVAQSTNTNKPDCDPTKPRLEK
>NZ_CP046266.1|WP_136352540.1|4816210_4816315_-|YjcZ-family-sporulation-protein
MGQEGGGYAGGFALIVVLFILLIIVGAAYVGGGY
>NZ_CP046266.1|WP_136352539.1|4816545_4816728_-|DUF4025-domain-containing-protein
MEKKTKLDSKQIAGRAYEVEDYNRQDELSSGLATTHEQASDDYMEGTIDAKLSNQDESRS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP046266_3	3.1\|4809168\|20\|NZ_CP046266\|CRT	4809168-4809187	20	NZ_CP046266.1	5150543-5150562	2	0.9

1. spacer 3.1|4809168|20|NZ_CP046266|CRT matches to position: 5150543-5150562, mismatch: 2, identity: 0.9

aatttcattagaactgtcct	CRISPR spacer
aatttcatttgcactgtcct	Protospacer
********* * ********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

320935 : 330913

Synechococcus_phage(37.5%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_136355695.1\|320935_322228_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	1.0e-18	24.9
WP_136355697.1\|322361_323081_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	E3SPA9	Prochlorococcus_phage	2.3e-49	42.2
WP_136355699.1\|323080_323335_+	phosphoribosylformylglycinamidine synthase subunit PurS	A0A0E3FKD5	Synechococcus_phage	5.5e-06	36.1
WP_136355701.1\|323331_324015_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_136355703.1\|323998_326227_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.7e-162	40.8
WP_136355705.1\|326202_327618_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.8e-53	33.5
WP_136355707.1\|327752_328793_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	1.6e-67	44.0
WP_136355709.1\|328789_329356_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.0e-27	37.7
WP_136355711.1\|329374_330913_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	5.3e-75	50.0

DBSCAN-SWA_2

1174300 : 1212184

Wolbachia_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_136359328.1\|1174300_1175661_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.1e-89	61.9
WP_136358910.1\|1176021_1176789_-	IclR family transcriptional regulator	NA	NA	NA	NA
WP_136358914.1\|1177001_1177286_-	hypothetical protein	NA	NA	NA	NA
WP_136358908.1\|1177421_1178495_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_136358906.1\|1178834_1180187_+	aromatic acid/H+ symport family MFS transporter	NA	NA	NA	NA
WP_136358904.1\|1180283_1180787_+	flavin reductase family protein	NA	NA	NA	NA
WP_136358902.1\|1180891_1181299_+	hypothetical protein	NA	NA	NA	NA
WP_136358900.1\|1182318_1183047_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_136358898.1\|1183727_1185038_+	amidohydrolase family protein	NA	NA	NA	NA
WP_136358896.1\|1185131_1185950_+	purine-nucleoside phosphorylase	Q5YBA4	Grouper_iridovirus	6.7e-61	47.1
WP_136358894.1\|1186108_1187395_+	NCS2 family permease	NA	NA	NA	NA
WP_136358892.1\|1187559_1188741_+	pyrimidine nucleoside transporter NupC	NA	NA	NA	NA
WP_155443841.1\|1189160_1189436_+	hypothetical protein	NA	NA	NA	NA
WP_136358888.1\|1189535_1190813_+	MFS transporter	NA	NA	NA	NA
WP_136358912.1\|1191219_1191444_+	helix-turn-helix domain-containing protein	S5MBY6	Brevibacillus_phage	3.0e-11	41.9
WP_136358886.1\|1191456_1191672_+	hypothetical protein	NA	NA	NA	NA
WP_136358884.1\|1191875_1192073_-	hypothetical protein	NA	NA	NA	NA
WP_136358882.1\|1192581_1192758_+	DUF2187 domain-containing protein	NA	NA	NA	NA
WP_136358880.1\|1193122_1194115_+	LacI family transcriptional regulator	NA	NA	NA	NA
WP_136358878.1\|1194496_1196188_+	alpha-glucosidase	NA	NA	NA	NA
WP_136358876.1\|1196180_1197626_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_136358874.1\|1198893_1199154_-	hypothetical protein	NA	NA	NA	NA
WP_136358872.1\|1199279_1199918_+	TVP38/TMEM64 family protein	NA	NA	NA	NA
WP_136359330.1\|1201461_1202685_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	3.8e-44	28.6
WP_136359330.1\|1203067_1204291_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	3.8e-44	28.6
WP_136359318.1\|1204840_1205983_-	YdcF family protein	NA	NA	NA	NA
WP_155443842.1\|1206362_1207598_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_136359332.1\|1208057_1208888_-	mechanosensitive ion channel family protein	NA	NA	NA	NA
WP_155443843.1\|1209258_1210476_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	7.7e-45	29.8
WP_136359322.1\|1210981_1212184_+\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

2393108 : 2430323

Wolbachia_phage(50.0%)

tail,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_136359322.1\|2393108_2394311_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_136359083.1\|2394678_2395068_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_136359085.1\|2395161_2395830_+	RCC1 repeat protein	NA	NA	NA	NA
WP_136359087.1\|2396047_2396530_+	hypothetical protein	NA	NA	NA	NA
WP_136359089.1\|2396810_2396978_+	DUF1540 domain-containing protein	NA	NA	NA	NA
WP_136359091.1\|2397135_2397291_+	DUF1540 domain-containing protein	NA	NA	NA	NA
WP_136359093.1\|2397463_2397712_-	hypothetical protein	NA	NA	NA	NA
WP_136359122.1\|2398118_2398676_+	hypothetical protein	NA	NA	NA	NA
WP_136359095.1\|2399247_2400210_-	HTH domain-containing protein	NA	NA	NA	NA
WP_136359097.1\|2400320_2400800_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_136359099.1\|2400822_2401287_+\|tail	phage tail protein	NA	NA	NA	NA
WP_136359101.1\|2401739_2402243_+	DUF664 domain-containing protein	NA	NA	NA	NA
WP_136359124.1\|2402382_2402805_+	metallothiol transferase FosB	Q2LI91	Bacillus_phage	1.8e-41	63.4
WP_136359103.1\|2402991_2403342_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_136359105.1\|2403490_2404075_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_136359107.1\|2404780_2404987_+	DUF2750 domain-containing protein	NA	NA	NA	NA
WP_136359109.1\|2405952_2407527_+	spore germination protein	NA	NA	NA	NA
WP_136359111.1\|2407554_2408658_+	GerAB/ArcD/ProY family transporter	NA	NA	NA	NA
WP_136359113.1\|2408641_2409853_+	Ger(x)C family spore germination protein	NA	NA	NA	NA
WP_136359115.1\|2410065_2410980_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_136359117.1\|2411004_2412027_-	iron ABC transporter permease	NA	NA	NA	NA
WP_136359118.1\|2412026_2413061_-	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	2.0e-14	25.0
WP_136359120.1\|2413584_2414001_+	hypothetical protein	NA	NA	NA	NA
WP_155443882.1\|2414108_2415326_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	7.7e-45	29.8
WP_155443883.1\|2418195_2418459_-	hypothetical protein	NA	NA	NA	NA
WP_136359271.1\|2420519_2420999_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_136359267.1\|2421154_2421328_+	spore germination protein	NA	NA	NA	NA
WP_136359265.1\|2421495_2422281_+	PhzF family phenazine biosynthesis protein	NA	NA	NA	NA
WP_136359264.1\|2422369_2422867_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_155443884.1\|2423142_2424345_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_136359312.1\|2424578_2424812_-	hypothetical protein	NA	NA	NA	NA
WP_136359310.1\|2425224_2425653_+	DUF4395 domain-containing protein	NA	NA	NA	NA
WP_136359308.1\|2425861_2426422_+	hypothetical protein	NA	NA	NA	NA
WP_155443882.1\|2426561_2427779_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	7.7e-45	29.8
WP_136359340.1\|2428220_2428685_+	DUF3291 domain-containing protein	NA	NA	NA	NA
WP_155443885.1\|2429087_2430323_-\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

2841180 : 2850272

Brazilian_cedratvirus(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_136354320.1\|2841180_2841948_+	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	2.0e-11	27.2
WP_136354321.1\|2841947_2842676_+	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	2.2e-10	27.2
WP_136354323.1\|2843242_2844205_-	D-2-hydroxyacid dehydrogenase	M1I636	Acanthocystis_turfacea_Chlorella_virus	2.1e-13	37.5
WP_136354325.1\|2844425_2846213_+	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	4.9e-48	23.9
WP_136354375.1\|2846523_2847963_-	vanadium-dependent haloperoxidase	A0A1V0SD32	Indivirus	4.7e-94	42.9
WP_155443893.1\|2848404_2848542_+	hypothetical protein	NA	NA	NA	NA
WP_136359330.1\|2849048_2850272_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	3.8e-44	28.6

DBSCAN-SWA_5

2964408 : 2971857

Bacillus_virus(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_136354560.1\|2964408_2965188_+	NUDIX hydrolase	G3MA14	Bacillus_virus	5.6e-33	39.4
WP_136354562.1\|2965203_2965752_+	cysteine hydrolase	G3MA16	Bacillus_virus	1.1e-35	44.4
WP_136354564.1\|2965820_2967299_+	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	6.5e-115	47.4
WP_136354566.1\|2967379_2967994_+	nicotinate (nicotinamide) nucleotide adenylyltransferase	G3MA22	Bacillus_virus	2.0e-49	46.9
WP_136354568.1\|2968006_2968825_+	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	1.2e-97	64.4
WP_136354570.1\|2968946_2969453_+	acyl-CoA thioesterase	NA	NA	NA	NA
WP_136354572.1\|2969676_2970138_-	hypothetical protein	NA	NA	NA	NA
WP_136354574.1\|2970402_2971857_-	catalase	A0A2K9L0T1	Tupanvirus	3.5e-113	42.2

DBSCAN-SWA_6

3516400 : 3525896

Staphylococcus_phage(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_136351135.1\|3516400_3517552_-	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	2.0e-18	27.0
WP_136351136.1\|3517761_3518358_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	9.0e-15	37.2
WP_136351137.1\|3518362_3519121_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	4.7e-08	27.1
WP_136351138.1\|3519290_3519386_+	YjcZ family sporulation protein	NA	NA	NA	NA
WP_136351460.1\|3519631_3520162_+	DUF309 domain-containing protein	NA	NA	NA	NA
WP_136351139.1\|3520304_3520658_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_136351140.1\|3520817_3521285_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.5e-49	67.3
WP_136351141.1\|3521387_3522002_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	4.9e-56	54.8
WP_136351142.1\|3522045_3522693_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	9.4e-42	46.2
WP_136351143.1\|3523261_3523696_-	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.1e-17	45.1
WP_136351144.1\|3523988_3524879_+	DUF1002 domain-containing protein	NA	NA	NA	NA
WP_136351145.1\|3524990_3525896_-	chemotaxis protein CheV	Q56AR1	Bacillus_thuringiensis_phage	1.5e-48	34.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP046266

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection