CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP046057	Bacillus sp. N3536 chromosome, complete genome	3 crisprs	cas3,WYL,DinG,DEDDh,csa3	0	1	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046057_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046057_1

468449-468556

Orphan

Consensus_repeat	Method
CATTGCGGGAAATAAAAGAGTTGCGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP046057_1

>merge|NZ_CP046057|1|468449-468556|CRISPRCasFinder
CATTGCGGGAAATAAAAGAGTTGCGGGAAATAAGGAAAGTGTTGCAGAGAAGGAGCAAAGTGTTGCGCGAAAGAGAGGGAGCATTGCGGGAAGTAAAAGAGTTGCGGG

>NZ_CP046057|1|1|468449-468556|CRISPRCasFinder
CATTGCGGGAAATAAAAGAGTTGCGGG	AAATAAGGAAAGTGTTGCAGAGAAGGAGCAAAGTGTTGCGCGAAAGAGAGGGAG
CATTGCGGGAAGTAAAAGAGTTGCGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046057.1\|WP_144538786.1\|466934_468227_+\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP046057.1\|WP_154310108.1\|459928_460450_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|224511
NZ_CP046057.1\|WP_154310115.1\|468866_470381_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|271381
NZ_CP046057.1\|WP_144538794.1\|462268_463276_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|223135
NZ_CP046057.1\|WP_154310107.1\|459198_459951_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046057.1\|WP_154310113.1\|465393_466932_+\|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|235463
NZ_CP046057.1\|WP_144538804.1\|458349_458796_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP046057.1\|WP_154310121.1\|481748_482765_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046057.1\|WP_144538776.1\|474106_474574_+\|SsrA-binding-protein-SmpB	unknown	unknown	gnl\|CDD\|376590
NZ_CP046057.1\|WP_144538782.1\|470577_470805_+\|preprotein-translocase-subunit-SecG	unknown	unknown	gnl\|CDD\|235881
NZ_CP046057.1\|WP_154310109.1\|460846_461080_+\|glutaredoxin-family-protein	unknown	unknown	gnl\|CDD\|368604
NZ_CP046057.1\|WP_154312281.1\|476282_476420_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|197775
NZ_CP046057.1\|WP_154310116.1\|470952_471699_+\|abhydrolase-domain-containing-18	unknown	unknown	gnl\|CDD\|224561
NZ_CP046057.1\|WP_154310119.1\|477584_478415_+\|DUF1837-domain-containing-protein	unknown	unknown	gnl\|CDD\|378078
NZ_CP046057.1\|WP_154310117.1\|471742_474055_+\|ribonuclease-R	unknown	unknown	gnl\|CDD\|273947
NZ_CP046057.1\|WP_154310110.1\|461217_462255_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225263
NZ_CP046057.1\|WP_154310120.1\|478356_481371_+\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|224125
NZ_CP046057.1\|WP_154310112.1\|464639_465401_+\|triose-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
NZ_CP046057.1\|WP_154310111.1\|463438_464623_+\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
NZ_CP046057.1\|WP_154310118.1\|475185_476154_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271175

Protein	Function_ID	Function_description	E-value
NZ_CP046057.1\|WP_144538786.1\|466934_468227_+\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP046057.1\|WP_154310108.1\|459928_460450_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	4.04188e-32
NZ_CP046057.1\|WP_154310115.1\|468866_470381_-\|hypothetical-protein	gnl\|CDD\|271381	cd11490, SLC5sbd_SGLT6, Na(+)/chiro-inositol cotransporter SGLT6 and related proteins; solute-binding domain. Human SGLT6 (also called KST1, SMIT2) is a chiro-inositol transporter, which also transports myo-inositol. It is encoded by the SLC5A11 gene. Xenopus Na1-glucose cotransporter type 1 (SGLT-1)-like protein is predicted to contain 14 membrane-spanning regions. This subgroup belongs to the solute carrier 5 (SLC5) transporter family.	0.00145245
NZ_CP046057.1\|WP_144538794.1\|462268_463276_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|223135	COG0057, GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism].	0
NZ_CP046057.1\|WP_154310113.1\|465393_466932_+\|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	gnl\|CDD\|235463	PRK05434, PRK05434, 2,3-bisphosphoglycerate-independent phosphoglycerate mutase.	0
NZ_CP046057.1\|WP_144538804.1\|458349_458796_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.50574e-15
NZ_CP046057.1\|WP_144538776.1\|474106_474574_+\|SsrA-binding-protein-SmpB	gnl\|CDD\|376590	pfam01668, SmpB, SmpB protein.	1.10282e-91
NZ_CP046057.1\|WP_144538782.1\|470577_470805_+\|preprotein-translocase-subunit-SecG	gnl\|CDD\|235881	PRK06870, secG, preprotein translocase subunit SecG; Reviewed.	3.18606e-12
NZ_CP046057.1\|WP_154310109.1\|460846_461080_+\|glutaredoxin-family-protein	gnl\|CDD\|368604	pfam05768, DUF836, Glutaredoxin-like domain (DUF836). These proteins are related to the pfam00462 family.	2.50985e-13
NZ_CP046057.1\|WP_154312281.1\|476282_476420_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	3.75161e-09
NZ_CP046057.1\|WP_154310116.1\|470952_471699_+\|abhydrolase-domain-containing-18	gnl\|CDD\|224561	COG1647, COG1647, Esterase/lipase [General function prediction only].	2.18078e-121
NZ_CP046057.1\|WP_154310119.1\|477584_478415_+\|DUF1837-domain-containing-protein	gnl\|CDD\|378078	pfam08878, DUF1837, Domain of unknown function (DUF1837). This family of proteins are functionally uncharacterized.	3.05914e-05
NZ_CP046057.1\|WP_154310117.1\|471742_474055_+\|ribonuclease-R	gnl\|CDD\|273947	TIGR02063, Ribonuclease_R, ribonuclease R. This family consists of an exoribonuclease, ribonuclease R, also called VacB. It is one of the eight exoribonucleases reported in E. coli and is broadly distributed throughout the bacteria. In E. coli, double mutants of this protein and polynucleotide phosphorylase are not viable. Scoring between trusted and noise cutoffs to the model are shorter, divergent forms from the Chlamydiae, and divergent forms from the Campylobacterales (including Helicobacter pylori) and Leptospira interrogans. [Transcription, Degradation of RNA].	0
NZ_CP046057.1\|WP_154310110.1\|461217_462255_+\|hypothetical-protein	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	1.67655e-67
NZ_CP046057.1\|WP_154310120.1\|478356_481371_+\|DEAD/DEAH-box-helicase	gnl\|CDD\|224125	COG1204, COG1204, Superfamily II helicase [General function prediction only].	5.29672e-41
NZ_CP046057.1\|WP_154310112.1\|464639_465401_+\|triose-phosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	1.48473e-146
NZ_CP046057.1\|WP_154310111.1\|463438_464623_+\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NZ_CP046057.1\|WP_154310118.1\|475185_476154_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271175	cd00397, DNA_BRE_C, DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine based site-specific recombinases (integrases) that share the same fold in their catalytic domain containing conserved active site residues. The best-studied members of this diverse superfamily include Human topoisomerase I, the bacteriophage lambda integrase, the bacteriophage P1 Cre recombinase, the yeast Flp recombinase, and the bacterial XerD/C recombinases. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. The enzymes differ in that topoisomerases cleave and then rejoin the same 5' and 3' termini, whereas a site-specific recombinase transfers a 5' hydroxyl generated by recombinase cleavage to a new 3' phosphate partner located in a different duplex region. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	6.06477e-26

>NZ_CP046057.1|WP_144538786.1|466934_468227_+|phosphopyruvate-hydratase
MPIITQIQAREVLDSRGNPTVEVEVFTESGAYGRAIVPSGASTGEYEAVELRDGDKSRYLGKGVLKAVENVNNVIAAELEENFSVLDQVEIDHAMIELDGTENKGNLGANAILGVSIAVAHAAADYLDVPLYQYLGGFNAKQLPVPMMNIVNGGEHADNNVDIQEFMIMPVGAESFRHALRMGAEIFHSLKSVLKDAGLNTAVGDEGGFAPNLKSNEEALSTIMTAIEKAGYKPGEEILLAMDVASSELFNKEDGKYHLTGEGVVKTSEEMVDWYEELCNKYPIISIEDGLDENDWAGHKLLTERLGKKVQLVGDDLFVTNTKKLAQGIEQGVGNSILVKVNQIGTLTETFDAIEMAKRAGYTAVISHRSGESEDVTIADLAVATNAGQIKTGAPSRSDRVAKYNQLLRIEDQLYNTAQYLGKKTFYNLK
>NZ_CP046057.1|WP_154310113.1|465393_466932_+|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase
MSKSPVALIILDGFGLRPETYGNAVFHAKKPNFDRYWNEFPNATLIASGEAVGLPDGQMGNSEVGHLNIGAGRIVYQNLTRIHKSIRDEEFFKEQKLLAAIEHVKQTGGKLHLMGLLSDGGVHSHYSHLFALLKLAKAQGLNDVFVHGFLDGRDVGPRTAVGYVEETEKQMKDIGIGQFASISGRYYAMDRDRRWDRVVLAYKAMVDGDGKTAETATQGVLNSYEEDIADEFVVPFVIEKNGQPATTIDTGDAVIFFNFRPDRAIQLSMALNTPSFDSFPLSEKHPKNLKFVTFTHYSDEVVADVVFEKVNLSNTIGGVLAARDKRQLRIAETEKYPHVTFFMSGGREEPFPGEQRILINSPKVATYDLKPEMSAYEVTDALVGEIALDKFDAIILNFANPDMVGHSGMLEPTVKAIEAVDTCLGKVVDAILAKGGQAIITADHGNSDEVVTIEGNPMTAHTTNPVPVIVTEKGATLRTDGILADLAPTMLHLLGIEAPPEMTGKTLIETES
>NZ_CP046057.1|WP_154310112.1|464639_465401_+|triose-phosphate-isomerase
MRKQVIAGNWKMYKTLSEAKQFASELKAKQLDTTNVEAVICAPSLFLESLVNETKGSFISIGAQNMHEEKEGAFTGEVSGQQLQDIGVSYVVIGHSERRQYFNETDESVNKKAKAAFENNLTPIICVGESLEQRESNETESIVSAQTTAALEGLTEEQVKNTIIAYEPIWAIGTGKTATADDANDVCRAIRETILDGFGEEVASAVRIQYGGSVKPENIEELLSKEDIDGALVGGASLQVDSFVKLLEAGANV
>NZ_CP046057.1|WP_154310111.1|463438_464623_+|phosphoglycerate-kinase
MKEKQTMSDVTLKGKRVFCRVDFNVPMEDGAITDDTRIRAALPTIQHLIEQGAKVILASHMGRPKGEVKEELRLTKVGEHLAKLLNKPVTKLDESIGEKVEHTISEMNEGDVVLLENVRFHAGEEKNDPELAKAFASLADVYVNDAFGAAHRAHATTEGIAKLLPAVSGLLMQKELDVLGKALTTPERPFTAIIGGAKVKDKIGVIDHLLDKVDNILIGGGLSYTFTKAQGHEIGTSLLEEDKIDLAKSFLEKAKEKGVNFYLPIDVVVADEFSKDANTKVVPIDQIPSDWMGLDIGPETVKLYDQVIKDSKLIIWNGPMGVFEIDAFANGTKGVANAMAETSGYTIIGGGDSAAAVEKFDVADKMDHISTGGGASLEFMEGKDLPGVSALNDK
>NZ_CP046057.1|WP_144538794.1|462268_463276_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MTVKLAINGFGRIGRKVFREALEQKDLEVVAINDLTDAAMLAHLLKYDSVHGISNADITSEGEYLVVNGKNIQVFAEKDPSVLPWKDLGVDIVIESTGVFSTVEKAGKHLEAGAKKVILSAPAKDNMPTFVMGVNEEKYNPETDHVVSNASCTTNCLSPVAKVLQDNFGIKRGMMTTIHSFTNDQRILDLPHSDYRRARAASESMIPTTTGAAAAVAKVLPELKGKLDGMAVRVPTPNVSLVDFVAELDKEVTVEELNKVLREASENELKGILEYNELPLVSIDYNGNTASSTVDGQSTMVLGDNLVKVLAWYDNESGYSARCIDLALLMAKKGL
>NZ_CP046057.1|WP_154310110.1|461217_462255_+|hypothetical-protein
MDSFLGAQLKLMPEMSDLLQKRYRILQTIQLTKGIGRRVLGEQLSLTERETRKELDALRTQGLIEVSREGASITAEGNEVLTELKEVVRLWSGRSQMELMLKKYLNIKDVIIVPGNVDNDTNTSMLLSQEAAKYLESILLNEHIIAVTGGSTIASISHAMTESSRWKDLLFIAARGGVGKDVRLQANTIASLFASKMNGSYRTLYIPDRLSEEAYMTMKKEPFIQEMMDLYKRTNIIIHGIGDALEMAKRRNSSDEEIELLRSRGAVSESFGYYFNNQGEAVHHIRTIGVQLNQLQHIEHLLAVAGGAKKANALISYFKQAPLQTVLVTDEGAANEMMKVIPKNI
>NZ_CP046057.1|WP_154310109.1|460846_461080_+|glutaredoxin-family-protein
MIVHFYTRPGCHLCDDARMMLKLVQEDVPFQIEEHNIEEDDQLHEKYMLMIPVVEYQGEIIQYGNVDYVTLMEALEN
>NZ_CP046057.1|WP_154310108.1|459928_460450_-|sigma-70-family-RNA-polymerase-sigma-factor
MEMEQLYRDHSDRVYGYIYLLVRHRECAEDLTQETFYKAFKGVDSFNKQASTATWILKIARNVTYDYFRRKRVIQFFSFEKEHDLETKALSPEGSFEQKEQLTRMYDSLRLLKKDYQEVIILRKVQECSIQETAFILGWTEAKVKMKMMRALEALKKEFHQKGGYADGTVKGI
>NZ_CP046057.1|WP_154310107.1|459198_459951_-|hypothetical-protein
MEPSKEFDELFADMKNVERSNEARRNTWLAVKGRMEKKKRRVFPAIISLAIVAIASFLIITYLMPSEPEQTAKSLTNEEVIMAVLEREYNGPDEELERLMQEWFDLQSKTSAESQEEYDKLLDSKEYKDYMNYYYSSFSEYFTENELKQAINTVMVFKYNHFLLDNDISIHLEKVQIEQEKDHPNIYRPIVEISLTNSQGQKISHTLKEEFIFSKTEPGKIGRYNVIRDPDGAPLRDKIENFDAYVNTDK
>NZ_CP046057.1|WP_144538804.1|458349_458796_+|GNAT-family-N-acetyltransferase
MKLVEINKDNWRKIVFLSTNEDGKATIVEKFVASNALSIVQSVYETGWITRGIEVEDKLIGFTMYGLDEETSNYWLCRFMIDHQSQGKGYGRKAIELILNEIKQLDGCESIYLSTEPDNEAAIKLYESLGFQKTGKLNEGEAEFMLKV
>NZ_CP046057.1|WP_154310115.1|468866_470381_-|hypothetical-protein
MNKKLFAMTSIILLALIATVYWFTLKEETKLPSDNWSRTFLVDIPTSNYSNFQVLERENSYILALRNFKQQTIVSCDLDLSCKEARSLALTSTSTNAWSDETDSYYIKNYSLLHFNTKNGNQEIAQNVEDFVKSDDTLVYWTKDRQLTVLKDGQEQAYGMDEPIYDVKIFGNNIFAITKDTQGDRFTVYTLTNEPNQLFKFTSTASLVSSLNIIEQSKEEYMLLMDATIVSGGAKSKVIQQASFNLSPNQTIQLTKLKFEHEEDGRTLDDITQPTVLQQDGQTLVAFTATYAGNKNQVFMGPLTNGTIQATLLSKSGIRYERPVILDEQTVAFLEMNGSQRELVYTSSDPIKIEESKKISKEDYKQAAYTQFSKSFNGLMLVLFAFAWIILAFGISYLSTVILNRFKYERTYFLGFVIHVVSLLALQFFFLYRFTKVETIIANVPFITESWHFVGLLVVGAVLSVVPLFLARYNPEEEDYTYMILYATFMNLAIMFFLVGPYIF
>NZ_CP046057.1|WP_144538782.1|470577_470805_+|preprotein-translocase-subunit-SecG
MNTLLMTLLIIVSLALIVVVLLQSGKSAGLSGAISGGAEQLFGKQKARGMDLILHRATVVLAVLFFILTIAVTKF
>NZ_CP046057.1|WP_154310116.1|470952_471699_+|abhydrolase-domain-containing-18
MRITTPKPFFFEAGKRAVLLLHGFTGNSSDVRMLGRFLEKNGYTSLAPHYKGHGVPPEELLETGPKDWWKDVMKAYDRLKAAGYDEIAVAGLSLGGVFSLKLGYTVPVKGIVTMCSPMTMKTTDVMFEGVVKYAKEYKKYEGKSEEQIEEEVEEIRKNPMQTLGELREFVYEVRDHVDHIYAPLFVTQGKLDTVIDINSANYIYEQAESIEKKINWYEESGHVITLGPEKETLHEDILNFLESLDWNV
>NZ_CP046057.1|WP_154310117.1|471742_474055_+|ribonuclease-R
MENMKEQLLELMNSEEYKPMTTKELEDHFGLTEADDFKELVKTLVSMEDSGAVVRSRSNRYGVPSRMNLIVGSFIGHAKGFGFVTPEEAGMDDIFIPPTEINGAVNGDKVLVRVSKESSGDRREGTIIKITQRGISQVVGTFQDNKGFGFVIPDDKKVPMDVFVAKGDTLGAVDGHKVVVEITDWPNERKSATGIVTKILGHKNDPGVDILSIIYKHGITIDFPQEVIDQAEAVPDQIAEGDLEGRRDLRDEVIVTIDGADAKDLDDAVTVTKLPDGTYKLGVHIADVSHYVTEGSALDREAYDRGTSVYLTDRVIPMIPHRLSNGICSLNPQVDRLTLSCEMIINGSGMVTSHEIFQSVIRTTERMTYSDVYKILEEKDEALIERYKDLVPMFENMAELAAVLRKKREERGAIDFDFPEAKILVDEDGWPTDVAIRERTVAEKLIEEFMLAANETVAEHFKWMDVPFIYRIHEDPKPEKLQRFFGFLTNFGLVVKGTGNDIHPKALQEIIESIEGMPEEPVISTMLLRSLQQAKYYGECLGHFGLSTEFYTHFTSPIRRYPDLIVHRLIRTYLVNGDVSSATINHWGAIIDDIAEHTSKRERRAVDAERDTDALKKAQYMADKIGEEFEGIVSSVTNFGMFIELPNTIEGLVHVTNMTDDYYRFDDRQMMMIGERSGKQFRIGDEVTVRVSAVKPEEAAVDFEVVGMKKSFGRSTRKESPKVIHASKKGTGKDRKDKSQPGPKKGTNQKKKFYESVAKKSQKRKRPKKK
>NZ_CP046057.1|WP_144538776.1|474106_474574_+|SsrA-binding-protein-SmpB
MAKKHDDKPLAQNKKANHDYFIEETIEAGIVLQGTEIKSIRNGKVQLKDAFVRIRNNEAWISNMHISPYEQGNRFNHDPLRSRKLLLHKKQISSLIGETKREGYTIVPLKMYLKNGYAKVLIGIGKGKKDYDKRDTLKKKEAKRDIERAFKDAQR
>NZ_CP046057.1|WP_154310118.1|475185_476154_+|tyrosine-type-recombinase/integrase
MGRKHGIFSVKSEEVNISTKKKTVKRDGITIPQALETIYQQMRIAGNRIRTIESYDYIFNQFVQFNKLDYVEDITADSIYEYLGSLEVAQQTKLIRLKSIKAVLSKFHNNGWMKQKFWSTINIKIDKKIKKGAKASDIEKLIELIDQNTFIGFRDTVAVMTLFRTGIRIQTLGELKERHIDFENLYLNLDGSILKNHKFLKLPIDQELADLFKVLIKQNDKIRSYYNSENTNIIITQNGLPINNSKTSNNAISKQLNKYSKRFGLEDINAHAIRRGYAKKLLDAGASIAIISKALGHSDLGVTTQYLDLDVEEVASSLRDYL
>NZ_CP046057.1|WP_154312281.1|476282_476420_-|helix-turn-helix-domain-containing-protein
MKNNLKQIRKIKGITQKELAENLNVSKAMISMWENNSNEKMKNSP
>NZ_CP046057.1|WP_154310119.1|477584_478415_+|DUF1837-domain-containing-protein
MQLINHFDMEESEFCIYRIKETELQVLLNKLPREFRQCYVKNEDLEELVQLTGSSMQDILKDNYIPENKSVMSGEFGEIFSYFLLKERYLPISVDGPTKWIWKDDKDQAIQKTDVMLFKQEDIISANDLVVSAEIKAKATKSSNNQLENAVNDMKKDNISRLAVSLKWLKSKYLKDKDIDNSKKLDRFLNPSEFGTYQKDFKAIVVIDSDLLEEEIEKYKRVEDINFDHEIIIFALTGLKNCYETTYEKILFEGESFDDTSKPKEMDNSVTLLENI
>NZ_CP046057.1|WP_154310120.1|478356_481371_+|DEAD/DEAH-box-helicase
MIQVNLKKWITQSHSWKTFKEFQLPVENEANYTFLDRKDDFYISLFSTMMDLIEKKDFINNKSEILSVAKGLEIYSLKETKNHFDGINEEINLLYASALYYLAGYTSSAYILANLVSLNDSHNEFEIFLWEFLKKDLGEVFYSELLNGYLNSGENLRYLDTLMESIELEIVTALKNNPNDFITLLITKALIEEFIDNNVWTDLKENSNSIVDIRKIILNGLNNTPQIWSFFPSQRAAVKKGILTNNEISYSLQMPTSAGKTAICELIIYNFLNEYKSSRVLFLVPFRALAYELKNSLSEKLRNLNISVKSIYGGNTSNSSEEININDVDVLISTPEMIMALEGAIPNIYDEFSLVICDEGHLLDDINRGLDYELLLTKLRVSKKHGHFRKFVFLSAIIPNIEEINTWLGGNTSTVITSDYKPTQIDYAFLKENIDNFYLNVNPNLEEPDNYKLFKFLVKPEHQYINSETGRLNTYKLKNNIKRKSVATSLKATVTGTVALFTTTKKGKSGVYALAEETIHQINTLELPNPKDYANEIIINKLKEHFELVFGKSYILSDLCEKGVLFHHGDLPQDIREIIENAIRNSEIRMIICNNTLSEGVNLPIKTLVINSTHRTYMEGNKVIHKDMLVRELKNLIGRAGRAGKETKGTVIFVNPNSYDLFTQLIENNTEEVTGTLYEFIKTLAAVIEGQNEKIGNRFILDNETIEKFSEKYLKIIDSLDYSLVSLLTEEIEIDELELVINKFVSNTFAFYSTTEKQSETLENIFQLRGSILKDYIKTGEFIYLKRNNLSIRDYNRIFNLVDLNDDIWLKLESPVDEKWVTTIIDIITSFPSVSHSIEEFNKKNRNILNADILKNIIINWIKGTWYEDMAKYNSLEINDILSIQREVIDSLIEPYANKIINTVSMLLGDEIKQISLEAKNWVKYLAYGLSNRTQLDLVEIGLSDRSAIIKLDIFLKASNFHYTDKIKLIFFLKEKKHEIVSQLSTELTTVSLEKLITDIDTKL
>NZ_CP046057.1|WP_154310121.1|481748_482765_+|hypothetical-protein
MDKILYFPTINIPKSQWLMSALFYWDKVGSIVPLDFLERPHRLDKYMRELVHAELIEQVVPEQYLGSIPNLRKGFLDYIDNNPVFNHISGLGNMGLIGNGRLIQSTSLIHMGKLDDIGEELVRRGLATKQRGPWYSVESYTASNYMTYLATLLGTVTDYTPVTNSYKELSNFLEIPKKHNNRKALKEQLRARVLEKILPVPSVIDDPYDIFRFKEKHYDELRRFRNYIEDFILNLETFPDDLVDEKIKYFVSNSEDEIKYIKDRMHSFKWKDVNLTTICSVGSPTIFLMNEVVENSLMNTAGVTLGLLGAVSTALGKERLIDIKSKPLAYAAIIERNF

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Crispr_ID: NZ_CP046057_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046057_2

1806275-1806351

Orphan

Consensus_repeat	Method
CTATAATTACCTTCTTCAAAAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP046057_2

>merge|NZ_CP046057|2|1806275-1806351|CRISPRCasFinder
CTATAATTACCTTCTTCAAAAAATCGCCTCCAAATTTATTTATTCGCCATTTATCTATAATTACCTTCTTCAACAAA

>NZ_CP046057|2|2|1806275-1806351|CRISPRCasFinder
CTATAATTACCTTCTTCAAAAAA	TCGCCTCCAAATTTATTTATTCGCCATTTAT
CTATAATTACCTTCTTCAACAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046057.1\|WP_154311011.1\|1810707_1811025_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046057.1\|WP_154311010.1\|1809559_1809811_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046057.1\|WP_144542064.1\|1807392_1808631_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NZ_CP046057.1\|WP_154311009.1\|1808794_1809109_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046057.1\|WP_154311003.1\|1795037_1797617_-\|DNA-mismatch-repair-protein-MutS	unknown	unknown	gnl\|CDD\|235444
NZ_CP046057.1\|WP_154311015.1\|1814598_1815660_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372323
NZ_CP046057.1\|WP_154311002.1\|1793190_1795014_-\|DNA-mismatch-repair-endonuclease-MutL	unknown	unknown	gnl\|CDD\|234630
NZ_CP046057.1\|WP_154311012.1\|1813497_1813668_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046057.1\|WP_154311008.1\|1806498_1807059_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046057.1\|WP_144538216.1\|1816221_1816413_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227919
NZ_CP046057.1\|WP_154311004.1\|1798654_1799212_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377593
NZ_CP046057.1\|WP_144541791.1\|1803252_1803531_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046057.1\|WP_154311013.1\|1813793_1814063_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370161
NZ_CP046057.1\|WP_154311006.1\|1805652_1805844_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046057.1\|WP_144541795.1\|1800847_1801639_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP046057.1\|WP_154311005.1\|1799213_1800851_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046057.1\|WP_154311014.1\|1814083_1814278_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234688
NZ_CP046057.1\|WP_144541801.1\|1797978_1798518_-\|outer-spore-coat-protein-CotE	unknown	unknown	gnl\|CDD\|371168
NZ_CP046057.1\|WP_144541790.1\|1804091_1805147_-\|nitric-oxide-synthase	unknown	unknown	gnl\|CDD\|376957
NZ_CP046057.1\|WP_144541793.1\|1801883_1803101_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340897

Protein	Function_ID	Function_description	E-value
NZ_CP046057.1\|WP_154311004.1\|1798654_1799212_-\|hypothetical-protein	gnl\|CDD\|377593	pfam06042, NTP_transf_6, Nucleotidyltransferase. This family consists of several hypothetical bacterial proteins of unknown function. This family was recently identified as belonging to the nucleotidyltransferase superfamily.	8.08505e-75
NZ_CP046057.1\|WP_154311014.1\|1814083_1814278_-\|hypothetical-protein	gnl\|CDD\|234688	PRK00215, PRK00215, transcriptional repressor LexA.	5.30724e-18
NZ_CP046057.1\|WP_144542064.1\|1807392_1808631_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	2.91278e-31
NZ_CP046057.1\|WP_154311003.1\|1795037_1797617_-\|DNA-mismatch-repair-protein-MutS	gnl\|CDD\|235444	PRK05399, PRK05399, DNA mismatch repair protein MutS; Provisional.	0
NZ_CP046057.1\|WP_154311015.1\|1814598_1815660_-\|hypothetical-protein	gnl\|CDD\|372323	pfam12810, Gly_rich, Glycine rich protein. This family of proteins is greatly expanded in Trichomonas vaginalis. The proteins are composed of several glycine rich motifs interspersed through the sequence. Although many proteins have been annotated by similarity in the family these annotations given the biased composition of the sequences these are unlikely to be functionally relevant.	4.00361e-27
NZ_CP046057.1\|WP_154311002.1\|1793190_1795014_-\|DNA-mismatch-repair-endonuclease-MutL	gnl\|CDD\|234630	PRK00095, mutL, DNA mismatch repair endonuclease MutL.	0
NZ_CP046057.1\|WP_144538216.1\|1816221_1816413_-\|hypothetical-protein	gnl\|CDD\|227919	COG5632, COG5632, N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane].	0.000445973
NZ_CP046057.1\|WP_144541793.1\|1801883_1803101_+\|MFS-transporter	gnl\|CDD\|340897	cd17339, MFS_NIMT_CynX_like, 2-nitroimidazole and cyanate transporters and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Escherichia coli 2-nitroimidazole transporter (NIMT) and cyanate transport protein CynX, and similar proteins. NIMT, also called YeaN, confers resistance to 2-nitroimidazole, the antibacterial and antifungal antibiotic, by mediating the active efflux of this compound. CynX is part of an active transport system that transports exogenous cyanate into E. coli cells. The NIMT/CynX-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.19038e-144
NZ_CP046057.1\|WP_144541795.1\|1800847_1801639_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.45678e-83
NZ_CP046057.1\|WP_144541801.1\|1797978_1798518_-\|outer-spore-coat-protein-CotE	gnl\|CDD\|371168	pfam10628, CotE, Outer spore coat protein E (CotE). CotE is a morphogenic protein that is required for the assembly of the outer coat of the endospore and spore resistance to lysozyme. CotE also regulates the expression of cotA, cotB, cotC and other genes encoding spore outer coat proteins. The timing of cotE expression has been shown in Bacillus subtilis to affect spore coat morphology but not lysozyme resistance.	7.1232e-65
NZ_CP046057.1\|WP_144541790.1\|1804091_1805147_-\|nitric-oxide-synthase	gnl\|CDD\|376957	pfam02898, NO_synthase, Nitric oxide synthase, oxygenase domain.	0
NZ_CP046057.1\|WP_154311013.1\|1813793_1814063_-\|hypothetical-protein	gnl\|CDD\|370161	pfam08863, YolD, YolD-like protein. Members of this family are functionally uncharacterized. However it has been predicted that these proteins are functionally equivalent to the UmuD subunit of polymerase V from gram-negative bacteria. This family has been shown to belong to the WYL-like superfamily.	4.39424e-06

>NZ_CP046057.1|WP_154311006.1|1805652_1805844_-|hypothetical-protein
MITASLLIGGFLMPILCVIFCLNLVSILKKVKHEEKTTVNTFWLTISFTLIMWSIAILAAAGK
>NZ_CP046057.1|WP_144541790.1|1804091_1805147_-|nitric-oxide-synthase
MLNEAQDFMRLYYTETGKEEQELVARLKEIEEEINREGSYVHTAEELDFGAKVAWRNSNKCIGRLFWQSLTVIDKRDLHNEEDILKSLLDHIQYATNEGRIRPTISIFSPSDVRIWNHQLIRYAGYETEAGVIGDPDSLAFTKVCEELGWKGKGTKFDVLPLVIQVKDQPARFFDIPESYILEVSIRHPEMEWFQDLQLKWYAVPMISSMKLEIGGINYVAAPFNGWYMGTEIGARNLADDYRYNMLPSIAEKMGLNTKSNASLWKDRALVELNAAVLYSFKEDGVSIVDHHTAAHQFKKFEEIERDTGRDVSGNWTWLIPPMSPATTHIFHKPYNNEKLTPNYSYQPNPY
>NZ_CP046057.1|WP_144541791.1|1803252_1803531_-|hypothetical-protein
MTKDKMKGFVSLGALLSIFGLIMIFSSVHFGTSFADHWLSKEGGADTEIYLMRISGYTNNFLATGSILLGIGLVTIMYFYYKIINYNEKNNE
>NZ_CP046057.1|WP_144541793.1|1801883_1803101_+|MFS-transporter
MRREFELLTTPESNKKTITLLIIGIIFISSTLRAPLTAVGPIISYIREGLDISNVLAGFITTIPLLAFAIISPFAPRVARRLGMEMTLFLAILLLAVGIAIRSIGTPFFLLFGTALVGVAIAFANVLIPSFIKLKFPLQIGLLTGIFTVSMNLSAGIGAGISYPIAEGTSFGWQGALGFWSILAIVACLVWIPQIKKKQQLVTEGPDTNPVKAKSILKSPLTWSITLCMGFQSLIFYTTAAWIPEILQTQGMEAEKSGWMLSIMQFSQLPMTFLIPILAGRMKDQRILVAVYTICYLIGFTGLLYGSLSLAILWMVFLGLGGGASFGLVMMFFSLRSRTPMEAADLSGVAQSIGYLLAAIGPVFFGFVHDTTGSWNTPMILFIVTAILLFSAGMHAGRNRFVSEA
>NZ_CP046057.1|WP_144541795.1|1800847_1801639_-|ATP-binding-cassette-domain-containing-protein
MEPQKILSLVNVSKSFGNKQVLSGINLDVYEGQIIGYIGPNGAGKSTTVKLILGLIEGYSGMIEIFGENIQKSDYTYKKRIGYVPETAELYENLTAFEFLIFTGEMYGLTSEKAEEKAFSLMKEFGLEGAFHQRLSSFSKGMKQKVLIISSLLHDPDLLFYDEPLSGLDANSVMVIKEILAKLAEQGKTIFYSSHIMDVVEKISNRIVLLVNGEVVADGSFEELKQQSQEGSLEGIFNQLTGFTEHEEIAERFVQTVSEGKRL
>NZ_CP046057.1|WP_154311005.1|1799213_1800851_-|hypothetical-protein
MKDFASLRVLDRFRTVFLKLDIDYDMMRRILQLKLTMDSRRMPPIFNGSKVKKDGNQFLKSLWIYGLFGLILLTPFLFLGNSFLFSFTIMFSTLFLILMTSMISDFSAVLLDIRDKNILQPKPISNRTINAAKTMHILIYIVLLTGSFVAIPLVVSIFKFGILFALLFLLEIILISCLTVIFTAFVYLFILRFFSGEFLKDVINYVQIFLAIGMTVSYQLIARIFDIVNLDIGYSFAWWHLFLPPFWYAAPLELFFNGNDAFYTIVFSVLAIIIPIFAVLLYVRLMPAFENYLAKLQSDSNRRKKKARRLTTFWSKVLCRTSEEKVFYRFSSIMLKEERELKLKIYPMLGFAVVFPFIMLFNNLRFSSYEEVASGNSFMVIYFALIFVPSVIPMLEFSNYYKAHWIFYVAPIPTRATVYSATLKATIINYFMPILIPLSIVFLWIFSFRIWLDIIIALLVAVGLTIVSYWIFIKDPFPFSNTPKQAQDNSMIKVFGSMFLVGVMAFVHMIVTIVSLEWLYILVLIISISIGWKLTFYSRKQKVDA
>NZ_CP046057.1|WP_154311004.1|1798654_1799212_-|hypothetical-protein
MDIHTEQQITALIEADAWMMNLLRVVKNLKLPDWWICAGFVRSKVWDTLHNYEARTPLADIDVIYFDPTCLDEEMEKRIEQKLFAIRSDIPWSVKNQARMHEVNNLPPYKSATDGIANFPETVTALGVKLEGDKLILTAPHGVDDVLQMHVRPIPRFNASSDLKAIYERRMMNKNWKAIWPKVDV
>NZ_CP046057.1|WP_144541801.1|1797978_1798518_-|outer-spore-coat-protein-CotE
MKYLRHIVTKAVVAKGKKRTESCETLRPPNTPSSILGCWVINHTYQSKKHGKFVEVTGKFDINVWYAHHDHSKTSVFTETVNYKDRIKLSFRDKDSTGEEVHVRVIQQPNCTEAIIVNGQFQVTVERELLAEVVGETTVCIQVYDEDFEEEWSYEDESSSSSSSSSSSSSEDFHDSSSL
>NZ_CP046057.1|WP_154311003.1|1795037_1797617_-|DNA-mismatch-repair-protein-MutS
MTTITPMMQQYLKIKEDYIDAFLFFRLGDFYELFHDDAIKAASILEITLTSRKDGIPMCGVPHHAAQSYIETLITKGYKVAICEQVEDPKVAKGVVKREVVQLVTPGTLMEGKSLQNKTNYFIASADLLSTDEIVFSYLDVSTGDGFTTIIKGDEKEVVQQLLALQAKELIVSEQMYLVINELSSIHNFVLSIEQEELTGEEAEKYVKDHPVSTHRTVKRLLKYIQKTQKRSLLHIQPLTFQEREAFLAMDYHSKRNLELVSSIRNGDQKGTLLWLLDETVTAMGGRKLKQWIHQPLATKQAIESRLDIVTSFLDDFMLREEIKELFKEVYDLERLVGRIGFGSAGGRDLAQLRQSLSKIPQIKQLLLETQDETLQRLGEAIEDCQDIWRKLADAISDQPPISVKDGGVIKNGYNERLDQLRDASVNGKKWIAELEQREREITGAKNLKIGYNRVFGYYIELTKSNIHYADESRYVRKQTLANAERYITDELKEKESLILSAEDESLVLEYELFTELREEIKHYIPLVQKLAKQISELDVYISFAEVAEKHRLTRPVFHNSKAMIIKEGRHPVVEKMMNNQLYVPNDCVLTEEENMMLITGPNMSGKSTFMRQVAITVIMAQIGCYVPAKSAELPIVDKIFTRIGAADDLAGGQSTFMIEMMESQHAIVNATSNSLLLFDEIGRGTSTYDGMSLAQAMMEYIHNHIGANTLFSTHYHELTELEQTLSHLRNVHVAATEKDGKVVFLHKLQDGPADKSYGIHVAELAMLPEGIISRAREILDTFEQQDKKESKKENEANTQLSFFDELPTPSTATKIVEAKTSDNETTEKIVKRLKKVNISGTTPLEALQLLYELQNELD
>NZ_CP046057.1|WP_154311002.1|1793190_1795014_-|DNA-mismatch-repair-endonuclease-MutL
MGKIVVMEELLSNKIAAGEVVERPASVVKELVENAIDAESTSIEIMLQEAGLAEIQVTDNGKGMDEEDALRSFSRHATSKIMTEHDLFRIRTLGFRGEALASIASVSKILLWTSNGENIGTKVELEGGKIQSCTPAPIRRGTDIVVKQLFFNTPARLKYLKTIQTELGHTIDLINRLALSFPKIAFKLSHNDQTILQTSGRGDLRQVLASIYGVSNARKMIKFEAESSDFKISGYGTLPEVTRASKNYMTILVNGRWVKHYGLNNAIVEAYHTLLPIGRYPIVVLNIETDPMLTDVNVHPAKHQVRLSKEKELMELVKKTIRSVMHRSQQPPEIKEKPVRPKPQPSYQFDFFKQTYESVKPPQNEEQDTTIPIATSTPLGPEDTNWGGTPKVYEESSPLTEEVYPEEIIEQKEPFPDLHVVGQIHGTYIVAQSEDGFYLIDQHAAQERVKYEYYKEKVGEVDATERQALLLPLTFHYSLDESYRIKESLEELHKVGIFLEEFGSSSFVVRDHPAWFPKGHETKIIEGLIEQVLTNRKTDIKKLREEAAIMMSCKLSIKANHYLTLHDMEQLLVSLKNAKHPLTCPHGRPVIVHFSTYEIEKMFKRVM
>NZ_CP046057.1|WP_154311008.1|1806498_1807059_-|hypothetical-protein
MKTQYFVQYSNDSIINRFVIPKETFTSISIGIRNVGTDFIFPLVQNMFSFPIFFVLENDIFEQGKSIISERNIPSYKFSSNGFIIKIESVDTLEAICDISVDLALNGISVFIFFGQGLYDEDLVPLTQWNKPIEFKNLDFQKVETFIDVSEVGTTIFSRNNKFNSPRKVSYFISASYFLDIENSDI
>NZ_CP046057.1|WP_144542064.1|1807392_1808631_+|IS110-family-transposase
MNPVVGLDVAKGESQVQMFLDKKMPYKNSVKIQHTVEGLEELHAYLLDLERKTGLKPPVVLESTGHYHAPVVQFLEAQEYIVIIVNPLVSYRAKSSNLRKTKTDAIDAYHLGELYYKEDLEPQKKRGIQLLNLRHLTRQHENMTGIMVQTKLQFQAILDQVFPEYKGVYGDLYAEISLRTLQSFPTSESVLKAGVEEIAQFIDKHCKARSFNWAYERAEDLIAAAERNPFQSTLYQSLLVSLNMYIDLLQAYRQQLSTLEREMDQLAAQLEEYELIQSLPGIGEKIAATILSEIGEIERFNHPKKLVAFAGLDPSVFESGRFKGTKNHITKRGSARLRHTLYTAVRCSIRDSRKKKTTDETIARNKRLRSFYDLKRDEGKPYKVAVIACANKLLHWIYAILKTKTPFQETIK
>NZ_CP046057.1|WP_154311009.1|1808794_1809109_-|hypothetical-protein
MVFGILMIILGFSHLMKSDYFLSKKTRILLGEEKFQSYQKGLVFPNLFTGILIICMTIVEKLEILQTSTFIALYIILAIIPIILLIANNKINTGRYWFWVNDFK
>NZ_CP046057.1|WP_154311010.1|1809559_1809811_-|hypothetical-protein
MASYVLLLKEYEDDETVVYKFGPNEEFMGKIELNKITRKFSELESLPDQNIPSKFYFDRAAQRLAVCLVRENGIFPDKTAFES
>NZ_CP046057.1|WP_154311011.1|1810707_1811025_-|hypothetical-protein
MFIKYDEYDLLGLFQSEPVSITGNIDDGELLYTYKDETNFKVILTLDVYKQTSSLSITFNDSIVFTGDFNNVTNIKKDDKAFLIYVGEEARIKVKFYKQIGVELL
>NZ_CP046057.1|WP_154311012.1|1813497_1813668_-|hypothetical-protein
MDRTEELLNKLLDEHSLEVILGALEEMSRMNREELIINRAGSTEPEKAKNHKKTRF
>NZ_CP046057.1|WP_154311013.1|1813793_1814063_-|hypothetical-protein
MSIHDEFFEEIKKSKYPIDPRRNIKWGTSMMLTEHVVMLRDYHEEVKREPKPELTEYHYVTLSEAIELAYTTKGDTKIKRWKDGQFIYN
>NZ_CP046057.1|WP_154311014.1|1814083_1814278_-|hypothetical-protein
MKKRQQDIYDFIEEYISERHYSPTVREIAKAVGLSSTSSVNGHLNRMRRRGTLILLILVQGPYK
>NZ_CP046057.1|WP_154311015.1|1814598_1815660_-|hypothetical-protein
MLREEGQSSRKNSLFRTKRLPKYFIIFALTTISFVTGISNAFAATIVELDYTGHVQSWIAPKAGKYQLEVWGAQGGQSGWNGTEGMKGAYSSGSIELKEGESLEIYVGGAGNPGNYGNHSSGGWNGGGEGGLYHGGSGGGATDIRKDGISDNDRIIVAGGGGGAGQENDQGFSTDIGGNNSSTGEKGIYDNGGGGGGFLGGKSGTGGPDGQNSGTDDQGGSSGSSFFGILKDGVIQYYVREGNGYAKITLIELQQAVKEREIVDTTPPKTKIEINSSSLVEDLYNSDVTIYLSATDDLSGVNRIEYKIDGGEWITYNEVVILTKDGVTAFEYRSIDNEGNTEATNYVSINIKK
>NZ_CP046057.1|WP_144538216.1|1816221_1816413_-|hypothetical-protein
MVSLNYEVKHIKKHHTTRTGNKLLKVMADVIHFTANNGGTADNHFTYFNTTLPNANDKLPTDK

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Crispr_ID: NZ_CP046057_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046057_3

3821799-3821912

Orphan

Consensus_repeat	Method
TATTCATAATTTTCCAGAGGGGATTGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP046057_3

>merge|NZ_CP046057|3|3821799-3821912|CRISPRCasFinder
TATTCATAATTTTCCAGAGGGGATTGCCACTTTTGCTTCAGCATTACAGGATCCTAATCTTGGTATAGCAATTGCTATTGCGGTAGCTATTCATAATATTCCAGAGGGGATTGC

>NZ_CP046057|3|3|3821799-3821912|CRISPRCasFinder
TATTCATAATTTTCCAGAGGGGATTGC	CACTTTTGCTTCAGCATTACAGGATCCTAATCTTGGTATAGCAATTGCTATTGCGGTAGC
TATTCATAATATTCCAGAGGGGATTGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046057.1\|WP_154312177.1\|3810038_3811676_+\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|236236
NZ_CP046057.1\|WP_144539471.1\|3816042_3817530_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225646
NZ_CP046057.1\|WP_144539489.1\|3826717_3827989_+\|propionyl-CoA--succinate-CoA-transferase	unknown	unknown	gnl\|CDD\|188463
NZ_CP046057.1\|WP_151113835.1\|3820687_3821314_+\|uracil-DNA-glycosylase	unknown	unknown	gnl\|CDD\|381680
NZ_CP046057.1\|WP_154312180.1\|3817605_3818448_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046057.1\|WP_144539477.1\|3819998_3820616_+\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|239486
NZ_CP046057.1\|WP_154312185.1\|3828772_3829567_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|182263
NZ_CP046057.1\|WP_154312176.1\|3808702_3809872_-\|methyltransferase	unknown	unknown	gnl\|CDD\|379330
NZ_CP046057.1\|WP_154312183.1\|3823611_3824670_-\|threonine-synthase	unknown	unknown	gnl\|CDD\|236013
NZ_CP046057.1\|WP_151112403.1\|3814189_3815908_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP046057.1\|WP_154312178.1\|3811859_3812606_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
NZ_CP046057.1\|WP_154312181.1\|3818841_3819741_+\|FAD-binding-protein	unknown	unknown	gnl\|CDD\|223566
NZ_CP046057.1\|WP_154312179.1\|3812618_3813890_+\|GTPase-HflX	unknown	unknown	gnl\|CDD\|274455
NZ_CP046057.1\|WP_144539485.1\|3824843_3826073_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340874
NZ_CP046057.1\|WP_154312186.1\|3829726_3830914_-\|NO-inducible-flavohemoprotein	unknown	unknown	gnl\|CDD\|237337
NZ_CP046057.1\|WP_154312184.1\|3827990_3828575_+\|DNA-3-methyladenine-glycosylase	unknown	unknown	gnl\|CDD\|187726
NZ_CP046057.1\|WP_144539496.1\|3831121_3831571_+\|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224870
NZ_CP046057.1\|WP_151112411.1\|3826164_3826740_+\|DNA-topology-modulation-protein	unknown	unknown	gnl\|CDD\|181235
NZ_CP046057.1\|WP_154312182.1\|3822634_3823612_-\|homoserine-kinase	unknown	unknown	gnl\|CDD\|234920
NZ_CP046057.1\|WP_144539498.1\|3831610_3832540_+\|manganese-dependent-inorganic-pyrophosphatase	unknown	unknown	gnl\|CDD\|235458

Protein	Function_ID	Function_description	E-value
NZ_CP046057.1\|WP_154312179.1\|3812618_3813890_+\|GTPase-HflX	gnl\|CDD\|274455	TIGR03156, GTP_HflX, GTP-binding protein HflX. This protein family is one of a number of homologous small, well-conserved GTP-binding proteins with pleiotropic effects. Bacterial members are designated HflX, following the naming convention in Escherichia coli where HflX is encoded immediately downstream of the RNA chaperone Hfq, and immediately upstream of HflKC, a membrane-associated protease pair with an important housekeeping function. Over large numbers of other bacterial genomes, the pairing with hfq is more significant than with hflK and hlfC. The gene from Homo sapiens in this family has been named PGPL (pseudoautosomal GTP-binding protein-like). [Unknown function, General].	3.30887e-180
NZ_CP046057.1\|WP_144539471.1\|3816042_3817530_+\|MFS-transporter	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	6.67036e-170
NZ_CP046057.1\|WP_144539489.1\|3826717_3827989_+\|propionyl-CoA--succinate-CoA-transferase	gnl\|CDD\|188463	TIGR03948, hypothetical_protein_FAEPRAM212_02812, butyryl-CoA:acetate CoA-transferase. This enzyme represents one of at least two mechanisms for reclaiming CoA from butyryl-CoA at the end of butyrate biosynthesis (an important process performed by some colonic bacteria), namely transfer of CoA to acetate. An alternate mechanism transfers the butyrate onto inorganic phosphate, after which butyrate kinase transfers the phosphate onto ADP, creating ATP. [Energy metabolism, Fermentation].	7.95749e-93
NZ_CP046057.1\|WP_151113835.1\|3820687_3821314_+\|uracil-DNA-glycosylase	gnl\|CDD\|381680	cd10030, UDG-F4_TTUDGA_SPO1dp_like, Uracil DNA glycosylase family 4, includes Thermotoga maritima TTUDGA, Bacillus phage SPO1 DNA polymerase, and similar proteins. Uracil DNA glycosylase family 4 includes Thermotoga maritima TTUDGA, a robust uracil DNA glycosylase that shares narrow substrate specificity and high catalytic efficiency with family 1, acting on double-stranded and single-stranded uracil-containing DNA. Members of this family possess four conserved cysteine residues required to coordinate the [4Fe-4S] iron-sulfur cluster. This family also includes the N-terminal domain of Bacillus phage SPO1 DNA polymerase. Bacteriophage SPO1 is one of a group of large, lytic, tailed bacteriophages of Bacillus subtilis, and contains hydroxymethyluracil (hmUra) in place of thymine in their DNA. It has been speculated that this UDG domain may help discriminate between hmUra containing SPO1 DNA and thymine-containing host DNA. Uracil-DNA glycosylases (UDGs) initiate repair of uracils in DNA. Uracil in DNA can arise as a result of mis-incorporation of dUMP residues by DNA polymerase or via deamination of cytosine. Uracil in DNA mispaired with guanine is one of the major pro-mutagenic events, causing G:C->A:T mutations. Thus, UDG is an essential enzyme for maintaining the integrity of genetic information. UDGs have been classified into various families on the basis of their substrate specificity, conserved motifs, and structural similarities. Although these families demonstrate different substrate specificities, often the function of one enzyme can be complemented by the other.	9.27627e-62
NZ_CP046057.1\|WP_151112411.1\|3826164_3826740_+\|DNA-topology-modulation-protein	gnl\|CDD\|181235	PRK08118, PRK08118, DNA topology modulation protein.	5.66628e-77
NZ_CP046057.1\|WP_154312185.1\|3828772_3829567_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|182263	PRK10140, PRK10140, N-acetyltransferase.	5.94285e-16
NZ_CP046057.1\|WP_154312176.1\|3808702_3809872_-\|methyltransferase	gnl\|CDD\|379330	pfam13679, Methyltransf_32, Methyltransferase domain. This family appears to be a methyltransferase domain.	6.11868e-45
NZ_CP046057.1\|WP_154312183.1\|3823611_3824670_-\|threonine-synthase	gnl\|CDD\|236013	PRK07409, PRK07409, threonine synthase; Validated.	0
NZ_CP046057.1\|WP_151112403.1\|3814189_3815908_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NZ_CP046057.1\|WP_154312178.1\|3811859_3812606_+\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	1.56858e-37
NZ_CP046057.1\|WP_154312181.1\|3818841_3819741_+\|FAD-binding-protein	gnl\|CDD\|223566	COG0492, TrxB, Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones].	2.24506e-38
NZ_CP046057.1\|WP_154312182.1\|3822634_3823612_-\|homoserine-kinase	gnl\|CDD\|234920	PRK01212, PRK01212, homoserine kinase; Provisional.	1.45136e-104
NZ_CP046057.1\|WP_144539485.1\|3824843_3826073_+\|MFS-transporter	gnl\|CDD\|340874	cd17316, MFS_SV2_like, Metazoan Synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters of the Major Facilitator Superfamily. This family is composed of metazoan synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters including those that transport inorganic phosphate (Pht), aromatic compounds (PcaK and related proteins), proline/betaine (ProP), alpha-ketoglutarate (KgtP), citrate (CitA), shikimate (ShiA), and cis,cis-muconate (MucK), among others. SV2 is a transporter-like protein that serves as the receptor for botulinum neurotoxin A (BoNT/A), one of seven neurotoxins produced by the bacterium Clostridium botulinum. BoNT/A blocks neurotransmitter release by cleaving synaptosome-associated protein of 25 kD (SNAP-25) within presynaptic nerve terminals. Also included in this family is synaptic vesicle 2 (SV2)-related protein (SVOP) and similar proteins. SVOP is a transporter-like nucleotide binding protein that localizes to neurotransmitter-containing vesicles. The SV2-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.08466e-73
NZ_CP046057.1\|WP_154312186.1\|3829726_3830914_-\|NO-inducible-flavohemoprotein	gnl\|CDD\|237337	PRK13289, PRK13289, NO-inducible flavohemoprotein.	0
NZ_CP046057.1\|WP_154312184.1\|3827990_3828575_+\|DNA-3-methyladenine-glycosylase	gnl\|CDD\|187726	cd00540, AAG, Alkyladenine DNA glycosylase catalyzes the first step in base excision repair. Alkyladenine DNA glycosylase (AAG), also known as 3-methyladenine DNA glycosylase, catalyzes the first step in base excision repair (BER) by cleaving damaged DNA bases within double-stranded DNA to produce an abasic site. AAG bends DNA by intercalating between the base pairs, causing the damaged base to flip out of the double helix and into the enzyme active site for cleavage. Although AAG represents one of six DNA glycosylase classes, it lacks the helix-hairpin-helix active site motif associated with other BER glycosylases and is structurally distinct from them.	2.6353e-90
NZ_CP046057.1\|WP_144539496.1\|3831121_3831571_+\|Rrf2-family-transcriptional-regulator	gnl\|CDD\|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	1.84288e-46
NZ_CP046057.1\|WP_144539477.1\|3819998_3820616_+\|phosphatase-PAP2-family-protein	gnl\|CDD\|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	6.55103e-34
NZ_CP046057.1\|WP_144539498.1\|3831610_3832540_+\|manganese-dependent-inorganic-pyrophosphatase	gnl\|CDD\|235458	PRK05427, PRK05427, putative manganese-dependent inorganic pyrophosphatase; Provisional.	1.03143e-168
NZ_CP046057.1\|WP_154312177.1\|3810038_3811676_+\|AMP-binding-protein	gnl\|CDD\|236236	PRK08315, PRK08315, AMP-binding domain protein; Validated.	0

>NZ_CP046057.1|WP_151113835.1|3820687_3821314_+|uracil-DNA-glycosylase
MDLCIKRIEGYPVEGFVKGKGPRKPTLMLIGEAPGENEAIQGIPFIGRAGEELKKSLASIGLTREDVYMTSAVRSRPFVWREKKERNGEAVRKKYNRPPTQKEIIAHAPILDYEITNISPLLIVTLGNVGLQRLLGREATVSKLHGQLLQKPVQFLQSLNSSEFVWSTETYTIIPTYHPASVFYRPSNRDFLEEDWIKIGEYIKSQIL
>NZ_CP046057.1|WP_144539477.1|3819998_3820616_+|phosphatase-PAP2-family-protein
MKKWFYPLGLVTLLGFAMLYLNITKDEVVSLDHKMSNLLGGSQFITAFHYFGDTKFILLIALLIILLLWIRSHNYRGMLFVLFTVGVGNALNQLLKKVIQRERPDVSNQLETFSFPSGHAMVGLLYLFTIAYLATEHQTNKKISLTIWSGAILMTIMIGLSRIAESRHYASDVFAGWMAGYTWFILVAIWYELRKRNRKSKKNKL
>NZ_CP046057.1|WP_154312181.1|3818841_3819741_+|FAD-binding-protein
MYDCIIIGGGPAGLGAGLTLGRARRKVALFDDGTNRNRVTHESHGFITRDGIKPHEFKGIGLKELENYPNVSYFNKTIIEIGREGKEGNFIVRTRDNEEYVSEKLLLATGIQEMFTIESIRSFYGKSLFSCPYCDGWELRDKPLLILAEKEEHVLHMVKLIYNWSNDLMVLTNGKELSHEGMQELAKHNIEIKIEKIDELIGEAGYLKGVKLESGEIINRTQGFVAPTYYRPNYFAEKLGCEIDEKGRVMTDPRCRASQKNVYVAGETRKPIPSSLMIAAADGNKAAVSINTDLTEERF
>NZ_CP046057.1|WP_154312180.1|3817605_3818448_+|hypothetical-protein
MKKWKTLLAVTTLTFGLAACNETATPANKNVKETSEMTLEEVYNKSMAVSEELKSVSAKVDLAQKMHIPSEEMNVDISTAMDMNLIIEPMQIYQKGTTSMKSEDGSMNETMDTEIYFNDTDLYMYEGTTQQWMKLPQEAMGDVMAQTNSANPANSLAEIEEYLKDFKFEQDDKNYILTLDASGDKFNDLVQAQIDETMQSMAQAGEDVQLDVKINSINYLIHIDKESFQTTKYDVIVDMDMEAEGESINMKQDLKTDFSNFNGVDKIEIPQEVIDNAVAI
>NZ_CP046057.1|WP_144539471.1|3816042_3817530_+|MFS-transporter
MLSKEEIVKSVPQTGFFGQPKGLLSLFFTEFWERFSYYGMRAILIYYMYYEVTQGGLGLERSTANSIMAVYGSLVYMSGIIGGWIADRLFGTTRTVFYGGVLIMIGHIILAFPGGLTTLFLSMAFIIIGTGLLKTNISTIVGDLYSADDARRDSGFSLFYMGINMGAFVAPLIVGTIGLEYNFHLGFGLAAVGMAIGLVVFLTTKKKYLGLAGSYVPNPLSSEGKKKFFTRLAIGVVIIAALGFYLIQAGIMTIDVFTMTISILGILIPTLYFIVMYRSDKSTADEKSRLLAYIPLFVAAMMFWAIQEQGSNILAQYADERVDLTLGSFEISPAWFQSLNPLFIIALAPLFAWLWVKLGNRQPSTPRKFAYGLFFAGLSFVVMIFPAYFNGTDTLANPMWLVLSFFLVVLGELLLSPVGLSATTKLAPAAFAAQTMSLWFMTNASAQAINAQVVKLYKPETEIMYFGVIGAIAIGLGLILYVMTPLIQKYMRGIR
>NZ_CP046057.1|WP_151112403.1|3814189_3815908_-|ATP-binding-cassette-domain-containing-protein
MLKKFFSFYKPHKRLFIIDFSSAVFVAILELAFPVAVQWFIDDLLPTGNWATIVRVSIVLLFVYIISTVLQYVVSYLGHKLGINIETDMRQKLFNHVQRQSFRFFDNTKTGHIMSRITNDLFDIGELAHHGPEDLFIAIMTIIGAFTIMFNINPELAVIAIIMVPFLSIVATYGNIMMNKAWKNMYGKIADVNARVEDSVSGARVVQSFTNENFEISRFKEDNSQFRLAKLAAYKVMAGTHSSIYMMTRLVTLVVLVVGAWFSYQDYITSGELVSFILYVNVLIKPVDKITALLELYPKGMAGFKRFLELIEQEPEIVDKPNALQVQHLKGDISFDHVSFRYDDHQSVLKDINLSIQAGETVAFVGPSGAGKTTICSLIPRFYDVNEGAISIDGLNIQDLALHSLRSQIGIVQQDVFLFTGTIRENIAYGKRDATDEEIHSAAKKAHLESLIASLPDGYDTQIGERGLKLSGGQKQRLAIARMFLKNPPILILDEATSALDTETEKIIQQSLMELAENRTTLIIAHRLATIRDADRVIVVTEEGIAEDGSYNELVAKDGIFARLHNIQFQQI
>NZ_CP046057.1|WP_154312179.1|3812618_3813890_+|GTPase-HflX
MEELVEKAIVVAVKLQKDEHFDYELEELYNLAEALNVEVVGEMTQNLERVTSSHYVGTGKVEEIKNLFDAMDANLVIFNDELSPSQIRNLERDLECKVIDRTMLILDIFARRAKSNEAQMQVELAQLQYMLPRLVGLRASLGRQGGGTGGGFKNRGAGETKLELDRRKIEDQISKLKKELELIKDQRETQRKQRKKNNIPVVSLVGYTNAGKSTIMNQLLNKVGQEQSKQVFEKDMLFATLETSVRQIKLSDQKEFLLTDTVGFVSKLPHHLVKAFRSTLEEARDANLLLHVVDVSNEEHRYMMDVTNHTLLDVGVEDVPTIYVYNKSDLAELKYPYISGDNIWISAKEGKGLDELLEIIKKYIFSDYVQCNLLIPFDRGDIVSYLNENASVKSTSYEEEGTLVQVELKKSDYNRFEEYVYQL
>NZ_CP046057.1|WP_154312178.1|3811859_3812606_+|VOC-family-protein
MYLDHIVHFVEKNPLEIAEDWQQQGLHAVVGGQHINWGTYNALLYTKNSYIEWLSIEDEHIAQNTDHPLISLMLHDLKKSPGFGTICIRTSKIDVLKQELEEKGIETSGVLYAERKTTSGFVRKWKMLFIREEVSDQLPMPFFIEWQETDEDRYELLKKDGTIVESNLQLSIESCEFHVKKPREIIKKWEKYLNVEQYDDQTLLLPNTKLVFKQLEDGTKERLIRVQIKGDSRQEAIIYEQGEYRFKL
>NZ_CP046057.1|WP_154312177.1|3810038_3811676_+|AMP-binding-protein
MGLLNEKTIGEIVKEAASLFPNREAYVYPEHGIRKTYKEFDAETDELAKAFIGMGIQKGEHIAIWSDNKREWLLSQFATGKMGAVLVTVNTNYQEKELEYLLQQSDSTTLILCESFKSTSYLDIIRAICPEIITSEKGNIQSEKLPHFKRVIVMSENDYPGIYKWSEFVAFANKVSDEALEKSLEALHNDEVINIQYTSGTTGFPKGVMLSHKNIVNNGQLVGDYIHLTEHDRLCIPVPFFHCFGCVMGTIASVTHGTTMVIIEQFDAGKVLKMVQDEKCTALHGVPTMFIAELNHPDFKQFDLSSLRTGIMAGSICPIEVMKKVIEDMGASEITIAYGQTETSPVITQTKTDDAIEKRVSSVGKAHPGVEVKIIDPATGEDIPAGVPGELCTRGYLVMQGYYKNEEATNSTIDDNGWLHTGDIAVMDDEGYIDITGRIKDMVIRGGENIYPKEVEEFLYQHPSIQDVQVVGVPDQKYGEELMAWVILKSGENLTPEALREYCKGKISYHKIPKYIEFIDAYPMTASGKIQKFLLREMSKKRVEV
>NZ_CP046057.1|WP_154312176.1|3808702_3809872_-|methyltransferase
MEFLEMKEKVLDQILSKQLIQATVSQPRAKSNEIKRVKLKPIEIKNMYHIQLEYQYERILKHENILLEEFPAIWEKLLEDFRQFHADFLEEKLQIQLSKKNKVMFKAEKTASVKQVNLSHNRKKNYLLDEHTPYPFLIRLGVQTAEGKVKKQKYDKFKQINRFIEFIDDTLVYLPKDKTVRILDFGSGKSYLTFALYHYLKIEKGLDIRVTGLDLKKEVIEECSQIAKDLNYDQLEFLVGDINDYNEETAVDMVVTLHACDVATDMALARAVKWNASVILSVPCCQHELNKQLEAPNLDIMLKHGLIKERFSALATDSIRAEILNMVGYEAQLVEFIDLENTPKNILIRAYRTGHKPTSKQMEAYQQFKQMLNAQPFLENELKEYLKTN
>NZ_CP046057.1|WP_154312182.1|3822634_3823612_-|homoserine-kinase
MTWSISIPSSTANLGPGFDSIGIALDKYLELEVELASQLSIENLTENLPFVPNPADHLIVQSAVKTAAMHGLELPACTLKLKSEIPLARGMGSSASAIVAGIELANQLLELKLTAHDKLKIATMMEGHPDNAAASIFGGFTISSSTDNGEIHVFHSYHIEASFVLSIPQFELKTEKARNVLPDHYTRSIAAQASASANLLVAAFLSQSFEQAGIYMEEDLFHEPYRLGLIPQSKELKFAAKKAGAFGTCISGAGPTLLSLVQKGKEQEFISQMKDKFPSFDLVPVSINKTGIIATKNRINPSSSYAYSDTQIGKSEISDSQLSPI
>NZ_CP046057.1|WP_154312183.1|3823611_3824670_-|threonine-synthase
MAWQGLIEQYKEFLPVTENTPKLTLLEGNTPLIKLENLSNDLGIELYAKIEGVNPTGSFKDRGMVFAVAKAKEEGSKAVICASTGNTSAAAAAYAARAGMRAVIVIPEGKVAAGKLAQAYMYGAEVIQIEGNFDVALEMVRAISESSPITLVNSVNPYRIEGQKTASFEICDVLGSAPDYLAIPVGNAGNITAYWKGFKEYNEKKQTGLPKIYGFEAEGAAAIVQGKPIEFPETIATAIRIGNPASWDYAVAARDESQGLIEAVSDDEMLDAYKLIASREGIFAEPASCASIAGVIRSVKEGKIIPGSKVVAVLTGNGLKDPQTAIDVKVAPPHKIESNAPALSAFIEGVLA
>NZ_CP046057.1|WP_144539485.1|3824843_3826073_+|MFS-transporter
MTAVLEKNTKKVEKPLSKNKLLGIAGLAWMFDAMDVGILSFVIAALASEWALTPNEMGWIGSVNSIGMAVGALVFGVFADKVGRKKIFMITLILFSVASGLSALTTTLFAFMALRFLVGMGLGGELPVASTLVSESVAAKERGRVVVLLESFWAAGWIVSAVIAYFIIPEYGWRVALLITALPAFYAIYLRLKLPDSPQFTSKNTETRSIIQNMKDVWSKKFAKATLMLWIVWFTVVFSYYGMFLWLPSVMVMKGFSLIQSFEYVLIMTLAQLPGYFSAAWLIEKAGRKFVLVTYLLGTAASAFVFGSAESTAILIASGMLLSFFNLGAWGALYAYSPEQYPTVIRATGSGMAASVGRIGGILGPLLVGTLVTAGYEIGWIFGIFCIAIVIGVIAVIFLGTETKQIELE
>NZ_CP046057.1|WP_151112411.1|3826164_3826740_+|DNA-topology-modulation-protein
MERSRHKKVLIIGSSGAGKSTFSKQLAKKWNLPLIHLDSLYWNEGWVPTPKDEFIEIVKDKLEEEQWIMDGNFKSTLEWRTEYADLIIFLDFQRTLCTYRVLKRVWMHRGKTRDDMALGCNEKLDWEFLRFVWSFPKKVRPAILNVLEDASTQRDICILRNPKEVKAFLDTARTTNENIIGVHTNERQNIK
>NZ_CP046057.1|WP_144539489.1|3826717_3827989_+|propionyl-CoA--succinate-CoA-transferase
MKDKILSDRQIIEFIPPNADIILPLTNGEPHKLLDILEENANDLINVKVHQLLSLKQRPYMEGAFPDKLKHVSYFLSGATRKNFHQGLVDLVPNNFHEMPRILKTSTNLSMIMAVASPMDEFGYFSLGTQADIVSEFIGSVPFILEVNKHMPRTFGQNQIHISQILGYVENDRPLFEDVAPPIVEKDIKIAEYVTEMISNGDTLQIGIGSIPNAVVSLLKNHRHLGIHTEMFVDGIVDLVEAGAIDGTQKFTNKGKIVATFAHGSKKLYDFLDNNPSVEFLPVSVVNDPREIAKEERIVSINATTEVDLYGQCASETVAGKYYSSSGGQADFARGVRFSKEGKGFVCMTSTAKNDEISRIKLSLSPGSIVTTSKNDIDMIVTEYGVASMFGQPISKRAEQLIAIAHPKFREELTFEAKKMGFI
>NZ_CP046057.1|WP_154312184.1|3827990_3828575_+|DNA-3-methyladenine-glycosylase
MKPIEPSFFHQPTLELARDLIGKYIVHEHESGLLIGKIVETEAYMGAEDQAAHSFGNRRTKRTEVMFGEPGHIYTYQMHTHTLINVVSAPLGTPHAILIRAVEPVEGLEQMKENRRDLPMKQWTNGPGKLTKAMAITMEYYGHHWSKKPLYMTEGEKAISISTGPRIGIDNSGEAVHYPYRFWATDNPYVSKMR
>NZ_CP046057.1|WP_154312185.1|3828772_3829567_-|GNAT-family-N-acetyltransferase
MVKQFESKYIPLSNYFKKCIKKEFILTYEEIEAIIGQALPNAAYLSSSWWKKTKPPALHYFAWIDNGYSVKDVELGKSVIFHSSKELDDEEDDKEQDILVIREAELEDARPFINLQEAIFSETDFMLYGESDFQMTVQQIRKRMTSWKTSSNSILFLAIMNGQIAGFILLQGTHAPRARHRASLVVGVKKQFSRKGIATSLINRAFLWAKEVGVTKLELSVIKENAIAHKLYQKAGFEKEGTRKNSLLINGQYVDEYYMGRIIE
>NZ_CP046057.1|WP_154312186.1|3829726_3830914_-|NO-inducible-flavohemoprotein
MLSQKTIDIVKSTVPVLEVHGVAITTTFYRNLFEAHPELLNIFNHANQEKGRQQNALANTVYAAAVHIDNLAAIIPVVKQIGQKHVSLGIKPEHYPIVGQYLLEAIKEVLGDAATDEIINAWAEAYGVIADAFIGIEEEMYVAAETQEGGWRFFKDFIIIDKVKESNNITSFYLQPADGSVLPSYEPGQYITVRVNIPGEQYLLNRQYSLSQAADLKSFRISVKKDDENNPEGKVSVHLHQNLNIGDKVEVSAPAGEFTLSKERTTPVTFISGGVGITPMMSMLETVTKSQPERAVSFIYSARTKNLHPFDQDIRSLMESLENGTYKTLYSEEGDGYITKEIIQEYAHLDGDVYVCGPVGFMEAMINHLLDIGLAKDNIHYEFFGPALNLNLKEV
>NZ_CP046057.1|WP_144539496.1|3831121_3831571_+|Rrf2-family-transcriptional-regulator
MRMTMYTDFSLRVLIYLGAKDKGELSTIKDISEAYGISKNHLMKVTYDLGKLGYIETIRGRGGGIRLAMRPEDINIGQVVRKTEDDFHLVECFDCQANRCVITPACGLRRALNRALKAYLMVLDEYTLADFLNNKDVLANLLFNDRQDI
>NZ_CP046057.1|WP_144539498.1|3831610_3832540_+|manganese-dependent-inorganic-pyrophosphatase
MEKVLVFGHQNPDTDTITSAIVYAYLKNAIGVEAEAVRLGELNNETKYALEKFGFEAPRLIKNVETEATKVILVDHNEKQQSAIGIEEVQITEVIDHHRIANFETADPLYYRAEPVGCTATIINKIFKEKGVDIPSNIAGLMLSAIVSDTLLFKSPTCTEEDITAARELEKMAGVNVEEYGLAMLKAGADLSDKSLEDLLSLDAKEFSMGEHKVIIAQVNAVDVNDVMGRQGQLEELINLEIQEKELDLFFFVVTDILNNDSVALALGKMALKAETAFNVTFVNNVALLKGVVSRKKQVVPALTEALAE

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP046057_2	2.1\|1806298\|31\|NZ_CP046057\|CRISPRCasFinder	1806298-1806328	31	MN694380	Marine virus AFVG_250M409, complete genome	25861-25891	8	0.742
NZ_CP046057_2	2.1\|1806298\|31\|NZ_CP046057\|CRISPRCasFinder	1806298-1806328	31	NZ_CP043831	Bacillus sp. BS98 plasmid unnamed1	170052-170082	8	0.742
NZ_CP046057_2	2.1\|1806298\|31\|NZ_CP046057\|CRISPRCasFinder	1806298-1806328	31	NZ_CP034564	Flammeovirga pectinis strain L12M1 plasmid unnamed1, complete sequence	28792-28822	8	0.742
NZ_CP046057_2	2.1\|1806298\|31\|NZ_CP046057\|CRISPRCasFinder	1806298-1806328	31	NZ_CP043831	Bacillus sp. BS98 plasmid unnamed1	257184-257214	9	0.71

1. spacer 2.1|1806298|31|NZ_CP046057|CRISPRCasFinder matches to MN694380 (Marine virus AFVG_250M409, complete genome) position: , mismatch: 8, identity: 0.742

tcgcctccaaatttatttattcgccatttat	CRISPR spacer
cagcagtaaaatttattttttcgccatttac	Protospacer
. **  . ********** ***********.

2. spacer 2.1|1806298|31|NZ_CP046057|CRISPRCasFinder matches to NZ_CP043831 (Bacillus sp. BS98 plasmid unnamed1) position: , mismatch: 8, identity: 0.742

tcgcctccaaatttatttattcgccatttat	CRISPR spacer
tcccctccaaattaatttattcgataagagt	Protospacer
** ********** ********* .*   .*

3. spacer 2.1|1806298|31|NZ_CP046057|CRISPRCasFinder matches to NZ_CP034564 (Flammeovirga pectinis strain L12M1 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

tcgcctccaaatttatttattcgccatttat	CRISPR spacer
tttacatgaaatttatttatccaccatttat	Protospacer
*.  * . ************.*.********

4. spacer 2.1|1806298|31|NZ_CP046057|CRISPRCasFinder matches to NZ_CP043831 (Bacillus sp. BS98 plasmid unnamed1) position: , mismatch: 9, identity: 0.71

tcgcctccaaatttatttattcgccatttat	CRISPR spacer
tcccctccaaattaatttattcgataagagc	Protospacer
** ********** ********* .*   ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

93925 : 102170

Synechococcus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_154309950.1\|93925_95224_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.2e-16	30.9
WP_144541596.1\|95271_95988_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3FUQ7	Synechococcus_phage	3.7e-47	43.8
WP_144541598.1\|95984_96239_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_154309951.1\|96235_96922_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_154309952.1\|96905_99137_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.6e-160	40.9
WP_154309953.1\|99112_100534_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.1e-54	33.3
WP_154309954.1\|100545_101601_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SR00	Cyanophage	4.1e-63	41.0
WP_154309955.1\|101600_102170_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	5.0e-23	37.0

DBSCAN-SWA_2

1776184 : 1783497

uncultured_Caudovirales_phage(28.57%)

holin,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_154310984.1\|1776184_1776853_-	hypothetical protein	A0A2H4J4U2	uncultured_Caudovirales_phage	1.9e-45	55.6
WP_154310985.1\|1776853_1777114_-\|holin	phage holin	A0A1Q1PW49	Staphylococcus_phage	5.3e-20	56.1
WP_154310986.1\|1777126_1777324_-	hypothetical protein	NA	NA	NA	NA
WP_154310987.1\|1777624_1778233_-	histidine phosphatase family protein	NA	NA	NA	NA
WP_154310988.1\|1778371_1778941_-	hypothetical protein	NA	NA	NA	NA
WP_154310989.1\|1778951_1779224_-	hypothetical protein	A8AT95	Listeria_phage	6.3e-16	52.3
WP_154310990.1\|1779445_1779790_-\|terminase	terminase	A0A2H4JBX8	uncultured_Caudovirales_phage	7.5e-06	36.2
WP_154312317.1\|1779946_1780225_-	HNH endonuclease	A8ATF8	Listeria_phage	3.4e-25	67.5
WP_154310991.1\|1780430_1781027_-	hypothetical protein	NA	NA	NA	NA
WP_154310992.1\|1781062_1781485_-	hypothetical protein	O64093	Bacillus_phage	6.2e-10	34.1
WP_154310993.1\|1781591_1781759_-	hypothetical protein	NA	NA	NA	NA
WP_154310994.1\|1781857_1782433_-	hypothetical protein	NA	NA	NA	NA
WP_154310995.1\|1782705_1782879_-	hypothetical protein	NA	NA	NA	NA
WP_144541825.1\|1783089_1783497_-	hypothetical protein	A0A288WG73	Bacillus_phage	3.3e-37	57.5

DBSCAN-SWA_3

3215933 : 3224732

Staphylococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_154311920.1\|3215933_3217373_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	7.7e-52	34.3
WP_144538323.1\|3217648_3217870_+	DUF2187 domain-containing protein	NA	NA	NA	NA
WP_154311921.1\|3217854_3219621_-	DNA helicase RecQ	A0A2K9L021	Tupanvirus	4.1e-79	35.9
WP_144538321.1\|3219661_3219907_-	hypothetical protein	NA	NA	NA	NA
WP_154311922.1\|3220184_3221378_+	RlmI/RlmK family 23S rRNA methyltransferase	W6LLI2	Streptococcus_phage	3.6e-79	42.7
WP_154311923.1\|3222075_3222501_-	hypothetical protein	A0A218KC79	Bacillus_phage	2.2e-07	34.0
WP_151111728.1\|3222641_3222977_+	metalloregulator ArsR/SmtB family transcription factor	NA	NA	NA	NA
WP_154311924.1\|3222995_3224291_+	arsenical efflux pump membrane protein ArsB	A0A2H4PQU3	Staphylococcus_phage	5.3e-161	67.1
WP_144538316.1\|3224312_3224732_+	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	8.5e-44	64.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP046057

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection