CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP045971	Listeria monocytogenes strain AUSMDU00000235 plasmid pAUSMDU00000235, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP045970	Listeria monocytogenes strain AUSMDU00000235 chromosome, complete genome	4 crisprs	DinG,cas3,csa3,WYL,casR,cas6,cas8b2,cas7,cas5,cas2,DEDDh	1	11	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP045970_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045970_1

554553-555137

Orphan

Consensus_repeat	Method
GATGTAAGTNATTTTGATACNAGTTCAGTAACTNATATG	CRT

7 spacers

The CRISPR arrays of NZ_CP045970_1

>merge|NZ_CP045970|1|554553-555137|CRT
GATTTGAGTGGTCTTGATACTAGTGCGGTAACTACTATGTGGGATATGTTTAACAGCTGTAGGGCACTTGAGGAACTGGATGTAAGTCATTTTGATACAAGTTCAGTAACTAATATGTCTTACATGTTTTATGATAATAGAAATCTTGAGGTGCTGGATGTAAGCAACCTTGATACGAGTTCAGTAACTAATATGTATGCCATGTTTGAAGATTGTACTAGTCTTGAAGAGCTGGATGTAAGTCATTTTGATACGAGTTCAGTAACTGATATGTATAGAGTGTTTAATGGCTGTGAAAAACTGAAGAAACTAGATGTAAGTAATTTCGATACCAGTTCCGCTACTGCAATGGTTCAAATGTTTAGAAATTGTAGCGCCCTTGAGAAGTTGGATGTAAGTAATTTTAATACGAGCTTAGTAACTGATATGCGTGCCATGTTTGCTGGTTGTACTAGTCTTGAAGTGTTAGATGTAAGTAATTTTGATACGAGTTCAGTAACTAATATGGCTGCCATGTTTTCTGATAATGAAAAAGTGGAGAAGCTTGATTTAAGTACCTTTGATACCAGTTCAGTGACTAACATG

>NZ_CP045970|1|1|554553-555137|CRT
GATTTGAGTGGTCTTGATACTAGTGCGGTAACTACTATG	TGGGATATGTTTAACAGCTGTAGGGCACTTGAGGAACTG
GATGTAAGTCATTTTGATACAAGTTCAGTAACTAATATG	TCTTACATGTTTTATGATAATAGAAATCTTGAGGTGCTG
GATGTAAGCAACCTTGATACGAGTTCAGTAACTAATATG	TATGCCATGTTTGAAGATTGTACTAGTCTTGAAGAGCTG
GATGTAAGTCATTTTGATACGAGTTCAGTAACTGATATG	TATAGAGTGTTTAATGGCTGTGAAAAACTGAAGAAACTA
GATGTAAGTAATTTCGATACCAGTTCCGCTACTGCAATG	GTTCAAATGTTTAGAAATTGTAGCGCCCTTGAGAAGTTG
GATGTAAGTAATTTTAATACGAGCTTAGTAACTGATATG	CGTGCCATGTTTGCTGGTTGTACTAGTCTTGAAGTGTTA
GATGTAAGTAATTTTGATACGAGTTCAGTAACTAATATG	GCTGCCATGTTTTCTGATAATGAAAAAGTGGAGAAGCTT
GATTTAAGTACCTTTGATACCAGTTCAGTGACTAACATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045970.1\|WP_003721255.1\|557417_557684_+\|transposase	unknown	unknown	unknown
NZ_CP045970.1\|WP_003733213.1\|561323_561566_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045970.1\|WP_003721249.1\|549900_551439_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|368260
NZ_CP045970.1\|WP_009930717.1\|538139_538895_-\|DUF4866-domain-containing-protein	unknown	unknown	gnl\|CDD\|379782
NZ_CP045970.1\|WP_003721250.1\|551690_553760_+\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP045970.1\|WP_003721253.1\|556523_557009_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045970.1\|WP_010989473.1\|541168_542317_-\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635
NZ_CP045970.1\|WP_003721261.1\|560572_560920_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045970.1\|WP_003733941.1\|557036_557342_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|273478
NZ_CP045970.1\|WP_014601265.1\|558509_558878_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045970.1\|WP_003721244.1\|545153_546437_+\|cytosine-permease	unknown	unknown	gnl\|CDD\|271377
NZ_CP045970.1\|WP_010989475.1\|543424_545020_+\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225306
NZ_CP045970.1\|WP_003721262.1\|561648_562626_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
NZ_CP045970.1\|WP_003721252.1\|556030_556504_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045970.1\|WP_057171529.1\|547530_549081_+\|hydantoinase/oxoprolinase-family-protein	unknown	unknown	gnl\|CDD\|223223
NZ_CP045970.1\|WP_003721245.1\|546437_547538_+\|DUF917-domain-containing-protein	unknown	unknown	gnl\|CDD\|226065
NZ_CP045970.1\|WP_012581921.1\|542321_543269_-\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NZ_CP045970.1\|WP_057171530.1\|539012_541172_-\|transglutaminase	unknown	unknown	gnl\|CDD\|376628
NZ_CP045970.1\|WP_003721260.1\|560272_560545_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045970.1\|WP_003721256.1\|558224_558509_+\|DUF3130-family-protein	unknown	unknown	gnl\|CDD\|288220

Protein	Function_ID	Function_description	E-value
NZ_CP045970.1\|WP_003721249.1\|549900_551439_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|368260	pfam05043, Mga, Mga helix-turn-helix domain. M regulator protein trans-acting positive regulator (Mga) is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This domain is found in the centre of the Mga proteins. This family also contains a number of bacterial RofA transcriptional regulators that seem to be largely restricted to streptococci. These proteins have been shown to regulate the expression of important bacterial adhesins. This is presumably a DNA-binding domain.	1.08327e-19
NZ_CP045970.1\|WP_009930717.1\|538139_538895_-\|DUF4866-domain-containing-protein	gnl\|CDD\|379782	pfam16160, DUF4866, Domain of unknown function (DUF4866). This family consists of uncharacterized proteins around 250 residues in length and is mainly found in various human gut Firmicute species and abundant in human gut metagenomic datasets. The function of this family is unknown.	3.03926e-122
NZ_CP045970.1\|WP_003721250.1\|551690_553760_+\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	1.08206e-30
NZ_CP045970.1\|WP_010989473.1\|541168_542317_-\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	2.48336e-53
NZ_CP045970.1\|WP_003721244.1\|545153_546437_+\|cytosine-permease	gnl\|CDD\|271377	cd11484, SLC-NCS1sbd_CobB-like, nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain. This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).	6.12636e-95
NZ_CP045970.1\|WP_010989475.1\|543424_545020_+\|PucR-family-transcriptional-regulator	gnl\|CDD\|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	1.08474e-59
NZ_CP045970.1\|WP_003721262.1\|561648_562626_-\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	2.52144e-45
NZ_CP045970.1\|WP_057171529.1\|547530_549081_+\|hydantoinase/oxoprolinase-family-protein	gnl\|CDD\|223223	COG0145, HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	1.32348e-105
NZ_CP045970.1\|WP_003721245.1\|546437_547538_+\|DUF917-domain-containing-protein	gnl\|CDD\|226065	COG3535, COG3535, Uncharacterized conserved protein [Function unknown].	0
NZ_CP045970.1\|WP_003721256.1\|558224_558509_+\|DUF3130-family-protein	gnl\|CDD\|288220	pfam11328, DUF3130, Protein of unknown function (DUF3130. This bacterial family of proteins has no known function.	4.16867e-42
NZ_CP045970.1\|WP_012581921.1\|542321_543269_-\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	3.27176e-102
NZ_CP045970.1\|WP_003733941.1\|557036_557342_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|273478	TIGR01167, Zinc_metalloprotease_ZmpB, LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other].	4.04229e-05
NZ_CP045970.1\|WP_057171530.1\|539012_541172_-\|transglutaminase	gnl\|CDD\|376628	pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine, and aspartate residues that form the catalytic triad in the structurally characterized transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologs of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.	1.38784e-27

>NZ_CP045970.1|WP_003721250.1|551690_553760_+|BspA-family-leucine-rich-repeat-surface-protein
MKKLSMRVILIVTVIFIACGSANVSIAQEMDIANKLPEEELGSLDTSNVNTEGVPQDKSAEVENLEEIPITDDLEQNPDVLEQPVADSDDSDLTVVDSGAYWTIYHNTANGEYSLHMFGNVPSSKPTAWNSYLNSIKHIEIEEATLIGDFSSYFRSFFFTALESVRIERSNLSGVKSFALAFYSSGIEKVIIRDNDYSTAPSLLTTEGMFKNCSNLTELDLSGLDTSAVTTMRDMFYSCSALEELDVSHFDTSSVTNMSYLFYDNEKLEKLDVSNFDTSLVTNMYAMFANCTSLEELDVSNFDTSSATDIYRMFESCVKLKKLDVSNFDTSSVTDMAYMFRNCSTLEKLDVSNFNTSSVTSMRAMFAGCTSLEALDISNFDTSSVTDMASMFLTCTSLEELDLSTFDTSLVDFMGYMFKDCTNLKTLYLNNFTDAASTIDMFTGTTSLTYLFVSHNFKVFNGLEDTNWYDEKNWVQFETVWQLQTYHWRQSEPIGYRKGAFLSLTMDAMGGQFEDMEEQKVQNKVFGDYWEEMLPVKDGHYFDGWYLDQYFTSKFDFSLPADASITIYAKWIENYTVVIPASIFLNETSELKVEGINRGDKTLSVGLNRTATSISESNELTLANTADTTVQCLAPLSWDGSENNPKNAILTLAPGSEITEGDAVMEIESPENIQAGKYTGNLVFSINYE
>NZ_CP045970.1|WP_003721249.1|549900_551439_+|helix-turn-helix-domain-containing-protein
MREYLDSKSQKKVALLEKIFYAENHTSTQEELLNDLNITYPTLISTIKTINFDIERFGYKAFSIVHSAPNLSYTLKISDNCSIQLIINAYIRESPKFQILETLLLASFPNLQALAKKVHVSYSGIKKEIKELNEELRERNLSISTGNQVEITGDEFSLRIFYAFLFLVTYSGDRWPFSFVQYDEITDLLESCPKEIYRANSIDKGMMIHYYVAMHLLRDRMNCQIDTTRQFKVALYKACTEESKKSESAFIKKVAKQLPNRNYKEITYTTQIILSTIVAFGSYSSIEKMPSFFYMDEQLEEMGFMKLVDFASERVNDNLSIPFSEKEMELLRYSFASINYRYFLLDNLINRFNNIVPGYTDLDRNIRKIHKVNHLEPLISQLVNLKEMRLLKPFEERLASDYLIILDKRIDFSIHTLPIKVTILSTISNETAVFDFMRYFSSYYNLEIINQVDPVVDLYISDFSVSPEVLTSLRINQPIVYVNTRWLESDYVKINDNLAKIARKKFIANKKD
>NZ_CP045970.1|WP_057171529.1|547530_549081_+|hydantoinase/oxoprolinase-family-protein
MYKIGIDVGGTNTDAVILDENQQLIHSVKMPTSEDIETGITESLHRVLSETGIDRSKVTHAMLGTTQCTNAIVERKKLAKVGVLRLGYPATASVLPYTAWPEDMVGFLSGKYKLTGGGYEYDGQVLSEINEAEIRETLASWKGEVESVAVVGVFSSLKNDQELAVQKIIEEELGANIPVSISSSVGSVGLIERENATILNAALFKVIAATSDGFEKALEQEGIAHAEIYLCQNDGTLMSLNYARQFPILTIACGPTNSIRGASYLAGLKDAMVLDVGGTTSDIGVLTDGFPRESSLAVDVGGVRTNFRMPDIISIGLGGGSIVRENDGDITIGPDSVGYRISEEALVFGGKTMTTTDIAVRLGVAEIGNPELVAHIPTDFAEKAYKKIAEMTEDAIDKMKTSSGSVSLVLVGGGSVIIPDEISGVVQIFRDKNGPVANAIGASISQISGQYEQIYIYSQIEREEALQDAEQKAREQATLAGAVTDSIEVVEVEEIPLAYHPGNATRLRVKVVGNLV
>NZ_CP045970.1|WP_003721245.1|546437_547538_+|DUF917-domain-containing-protein
MRYLDEQAIENIAIGAAFLGTGGGGDPYIGKMMALTAIKKHGPIKLLSPEEIADDDYFIPAAMMGAPSVLIEKFPKGDEFVRVFEKLGRYVGKEVKGTFPMEAGGVNSMIPIVVAAQLGLPMVDCDGMGRAFPELQMVTFHLDGISATPMAITDEKGNIGIMETIDNKWTERLARVTTVEMGASSLVSLYPCNGAQIKQSSIKNIVTLSEEIGKVIRETSMDEAEKLQKLLDVTHGYHLFEGKITDVVRETRAGFNFGRVKIDGLNKDTNSEVIVHFQNENLVAEKNGEPIAITPDLICMVDLETLMPVTTEALKYGKRVRVMALPADDAWRTDKGIETVGPRYFGYDVDFEPLEELVKKEERRHV
>NZ_CP045970.1|WP_003721244.1|545153_546437_+|cytosine-permease
MTEKKTVEQAQSWQSLAFVWTGAMICVPSLLVGGTLISGMPLWEAILIALLGYGVIVVFMIYQGMQSSDLGIPAVSVASQVFGEQGSKKIISILLAIACLGWFGIQANVCGAAFSQFLGIYGINLPVPVSSLIWGVIMLLSAIYGIRILSILNYIAVPILLFVCIYGLVVSLNNGGLAVVENYKPAGSMSFMTGLAITIGSFALGAVIAGDYSQYTKSRKDVVKAAIVGILPSGVLMIAVGAILALTAGTADISVVFTNLGLPVLGIIGLILAAWTTNAVNAFSGGIAIINVFNISEKYHKVAVAIAGGLGTVLAVIGILNHFVPIMSVLSAMVPPVAGVMIASYWIVQKGDKSKWAPVPGVNWLGVTSWLVGAVIAGIPVILTFFPALPQLPNQPLIGIILSLAVYLVGAKVLSGKTNNVENLEGK
>NZ_CP045970.1|WP_010989475.1|543424_545020_+|PucR-family-transcriptional-regulator
MSVKLADLMKLPSLKEAKVVSGKSGLSKLVSSISVLEYTEVALLEDDLFDNDEFYGSEIVVSAFVNIRDDVEAQCRTIERLHKVGEVALILYYVGIFVPKMDQKLIDFANELDFTIIVMPENEMSLRYSEVIYEVVEAIVKQEMTDTNFVTESLEQISSVRPPQRNIDTTLKILSDRTHSSLVLTDNSFQVINSITWPRTRHWDFERVIETSKQIDEHELVQLHLDERDFYTARKPIFQDGMQAMHLFMMKEKGALTADVVMQITEVVQVFMNLWGRNYVEISTAELMKAILNDESVKMRRLGKILNVDVSSIKWMWLVKTEEIRNNEQVLAELKSFVASHFQVSLIDLFEDNIVVLLDNSVGQRDRTHTANEFAMMMKEHGIDLKITVCQGMEQTSDVQSAYSLVNEYKNAANAIYANKSIYSLQEIDFAAKCVEIVDRGELAIAEQMRPLKSLEDNDELIETLSVFLLEGESNYNQAAELLFLHKNTIKYRIQRINELLQYPATKIPESYNLYLAVAIRRLLGGNNNNK
>NZ_CP045970.1|WP_012581921.1|542321_543269_-|MoxR-family-ATPase
MSIEPSIKINEIINEVEKVIVGKRHVVKLSLTALLAGGHVLLEDVPGVGKTMMVRTLSKTIGVSFKRIQFTPDLLPADVTGVSIFNPETRDFEFRPGPVMGNIVLADEINRTAPRTQAALLEGMAENSVTVDGITRKLANPFFVMATQNPIEYEGTYALPEAQLDRFLLKINIGYPTVEEEMQLLTLKQYQDPLDQTQQVVTLSELLDLKNKAKQVFIDDVLKNYIIRLVDATRKHPSVALGISPRGSLAFMQAAQAFALIEGRDYVIPDDIQYLAPYIFTHRLILKSEAYYNEETAESIIASILKNTSVPVEKR
>NZ_CP045970.1|WP_010989473.1|541168_542317_-|DUF58-domain-containing-protein
MLKKRLLLASRWIIMLIIYAGLWTYTLFQGDTASWFLTYFFSFILLLLFLSSIYPLKAWKVNRSFVKNTYHDGDLIDMQVSFTRKSRYPVGYLLFQQKIPATFGKVRARQQVVYPLFKKQFTVTLAGFVGVRGIHSFPPVDVETSDAFGLLERSRQLSSEKSLTIYPTYFPNVLEKISEASPENERNAAYWTLKKNSNLHSLREFSSGDRISLIDWKSSAKSDQLMTREFENSATSRLSVIFYGASHPNFELSLRAAYSFIRKISEENGEIRVTLLGDQTSKFAPAKGTSRLQDISTAFAEIAPVDSLTLQESLDSNLHSGEKILLFTPCMDTMLMQKVTRLTDNKQLQIITFQSEHSKAMDAPAIFLEQASLLSRWERETK
>NZ_CP045970.1|WP_057171530.1|539012_541172_-|transglutaminase
MKRYLTLVMLFILSVLLISEWIYPFAELTELSTATWIILFITLSLGSFFLRLKYYWTIPLHVVMIIIVSGIYYAKGGILAGNWLGSFFQITFNGFRDMVQFRSSDISMDFILIVFLIALWLLSYITTYSILRKQRIMSVLVLTVAYLAVINTFTDYNSNWAIVRTVLEGFLLLHLALASRIAAPNRISADSLKRNGLFYHIFVILLLAVFVFSSLMLPKKAPIFPDPIPTIKNALGINTTRTVGYSEDDTTLGGALKKDNATVFTARAEKGHYWRVESKTVYTGTGWANANSGDVISFSSGDNFPIQLTEKTTGATNTAEISFASSSDYMPYPYGTQAVNGAVDSFSANLTIERVGPVDTIKNYTVQLKTPVYNIEKMQNADFSTLSNTFVSQYTQTPKDLPDRVTKLANKVTKDADSIYDKTKAIEHYLSASGTFTYSTDDAKETPRGADYVDQFLFETQIGYCDNFSTSMVVMLRTLGIPARWAKGYTPGEGEKKENDAKTTYTITNNNAHSWPEVFFPGTGWVPFEPTATFSNPENFQEPTTETANKPETPNDSTSTPETPNTPDKTPEQDNGSSSTGETPKKEEPKTETATSNVEIPSWVWWIPAGLVVALLALAIVFRRRIRGYLLLRSLRNSPEFGKTYHRLMKLLASYGYVRESSETLRHFSARVDADLTTSEFSRLTKMYETQLYSKNLTEKVIAAEETQLVQQIIARLTK
>NZ_CP045970.1|WP_009930717.1|538139_538895_-|DUF4866-domain-containing-protein
MTTIFPKEQNVTPLFEQILANPTACRRFKDVFLDNLESYQETRGFEKDDTLFAKIILSAYRQSDVSALLLGVCGRTLFELLRQAFLIPKKLTVDNPFFLTDKEGNFIAKKDDISNREQEKFQEIYQSDLHHSETTIFLVDDDDIVHSYEPDFSISTKRINKKRGILVLYSLPDTLKSGMTESEVYAFIWKTFLHIQEIIPSSRIFYGQETSENADELGVFLPIHHFEKKMLQNIEQVNELVDALREQMVNK
>NZ_CP045970.1|WP_003721252.1|556030_556504_+|hypothetical-protein
MKKKRVVIISLLLLLVSVIGISSYFLFKDKINLLDVDHSAVDWNGKKQKDTSGEENTIAIPGFEKVTLYANETKQAVNFHNPEINDCYFKISLIHPDGSVLWISDLIEPGKGMYSIELEKTLAVGEYENAVLKYECFSLNDQSPLNGSEINLKLVVV
>NZ_CP045970.1|WP_003721253.1|556523_557009_+|hypothetical-protein
MNKLVLSTLSVAAMGMVFFSGGTAYAADKEGNTVVEYSVEGDYTLVVPEKVNLSNDNATEMSVKTINRNLEPGKEVEVTLSSGLSADGEIELQRVGAISDVITSSFKSNNSVVPMANPVIGSFSGYAMEETEVSKIQIGNPQGDKKAGAYQTTLTFTAAFK
>NZ_CP045970.1|WP_003733941.1|557036_557342_+|LPXTG-cell-wall-anchor-domain-containing-protein
MKRKLVLAMVLISFCGMFLLSPERVQASQTVVEVFISEDDLDVSEENIQEIPKKELAASSDKDNKQHMLPKAGDTVTNYTLLGLVLVLIWLIMQRKRKKKE
>NZ_CP045970.1|WP_003721255.1|557417_557684_+|transposase
MARIEYGEEIQKSLLVLYSRGSTIDSICKEYGIPRYEFHKWMKLHDADKLETKEVKTLLQIRELKQQKNKLEEEILFLNEAINLLESP
>NZ_CP045970.1|WP_003721256.1|558224_558509_+|DUF3130-family-protein
MREIKVDERTFQQHATKLASESTGSYLPLKNGNMAYSRANSIDQLRSALIELVDVVEDFQHVTKKDASRLKKMGIAYAKQDQLMGQKINQLEVR
>NZ_CP045970.1|WP_014601265.1|558509_558878_+|hypothetical-protein
MDSAHSQLEQQLQQIKKAKITAETDADQTRRKQNEQDWLEEDSNQLTQEKRVLLDFLRSGWQGEEASGFHRYLEEQQHEESQAWRRDLQDKRADLDTELQENKDKLHTLETKQATLQKEWSK
>NZ_CP045970.1|WP_003721260.1|560272_560545_+|hypothetical-protein
MTKKEQLYFLLNGLDNGEIEINNFTNQFMKIFDLEIDYDELSKEEYTILGNVSDMAARFSDSEEDLKLPNVYYSEKQIREEVTRSLEALA
>NZ_CP045970.1|WP_003721261.1|560572_560920_+|hypothetical-protein
MQKDTYNGIRLSVIQLIDSKKENLKENNIKLTIIKNEKDGYVVELDNDKCMAEIVVEEPTYAPYRYISFEVVSLMDGKVKIIYSWYDDETSQWSDIEKELNKGIQFLNNFKTMEQ
>NZ_CP045970.1|WP_003733213.1|561323_561566_+|hypothetical-protein
MKRIILTSTLIVWTIVCIYMSISMVSNNTGIAFPIWLHIILLICFLATSIVNVKKKEYLWSTMLFEGELVVLLSLIIVLV
>NZ_CP045970.1|WP_003721262.1|561648_562626_-|HD-domain-containing-protein
MKMTDPLYGTFEIEPVLAELIQSPLVSRLAHVHQGGSSYLVNPLWDLSRLDHSIGVMLFIRKFGGSLEEQIAGLLHDVSHTAFSHVVDYALDFEEEDYHEQIFEDFVKTSTIPAILEKYGYSFEGIFEDISKWKILEQEAPELCADRIDYTLQDLYRHGKISLAEVEGFLQALVMVNGRLYLANISSAEWFVKQYYSEVIDYFYDPLNVYSYEILAEAMRIAFQQETITTDDLRLTDAELLAKLNANSDAREKIQLLASPHLEENEVDFTYHHKKKMRLINPSVLVDGRLIPADELSEKVREMNDWASERSKHGIYIKATKKSKQ

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Crispr_ID: NZ_CP045970_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045970_2

593627-593909

Unclear

I-A

Consensus_repeat	Method
GTTTTAGTTACTTATTTTGAAATGTAAAT	PILER-CR
GTTTTAGTTACTTATTTTGAAATGTAAAT	CRISPRCasFinder
GTTTTAGTTACTTATTTTGAAATGTAAAT	CRT

4 spacers

cas6,cas8b2

The CRISPR arrays of NZ_CP045970_2

>merge|NZ_CP045970|2|593627-593909|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGTTACTTATTTTGAAATGTAAATAAACAGAAATGAAAGATGGTGAAGAAGTCCTTACCGTTTTAGTTACTTATTTTGAAATGTAAATTTTTTTAAGGCAAGTGTCATCGTTTCTAATCCGCGTTTTAGTTACTTATTTTGAAATGTAAATCTAGAACAAAAGAAAAATCATGAGGGATATTTACGTTTTAGTTACTTATTTTGAAATGTAAATGGTTTTGAATGCTGGTGGTGATAGTCCTAATGAAGGTTTTAGTTACTTATTATGAAATGTAAAT

>NZ_CP045970|2|1|593627-593909|PILER-CR
GTTTTAGTTACTTATTTTGAAATGTAAAT	AAACAGAAATGAAAGATGGTGAAGAAGTCCTTACC
GTTTTAGTTACTTATTTTGAAATGTAAAT	TTTTTTAAGGCAAGTGTCATCGTTTCTAATCCGC
GTTTTAGTTACTTATTTTGAAATGTAAAT	CTAGAACAAAAGAAAAATCATGAGGGATATTTAC
GTTTTAGTTACTTATTTTGAAATGTAAAT	GGTTTTGAATGCTGGTGGTGATAGTCCTAATGAAG
GTTTTAGTTACTTATTATGAAATGTAAAT

>NZ_CP045970|2|1|593627-593909|CRISPRCasFinder
GTTTTAGTTACTTATTTTGAAATGTAAAT	AAACAGAAATGAAAGATGGTGAAGAAGTCCTTACC
GTTTTAGTTACTTATTTTGAAATGTAAAT	TTTTTTAAGGCAAGTGTCATCGTTTCTAATCCGC
GTTTTAGTTACTTATTTTGAAATGTAAAT	CTAGAACAAAAGAAAAATCATGAGGGATATTTAC
GTTTTAGTTACTTATTTTGAAATGTAAAT	GGTTTTGAATGCTGGTGGTGATAGTCCTAATGAAG
GTTTTAGTTACTTATTATGAAATGTAAAT

>NZ_CP045970|2|2|593627-593909|CRT
GTTTTAGTTACTTATTTTGAAATGTAAAT	AAACAGAAATGAAAGATGGTGAAGAAGTCCTTACC
GTTTTAGTTACTTATTTTGAAATGTAAAT	TTTTTTAAGGCAAGTGTCATCGTTTCTAATCCGC
GTTTTAGTTACTTATTTTGAAATGTAAAT	CTAGAACAAAAGAAAAATCATGAGGGATATTTAC
GTTTTAGTTACTTATTTTGAAATGTAAAT	GGTTTTGAATGCTGGTGGTGATAGTCCTAATGAAG
GTTTTAGTTACTTATTATGAAATGTAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045970.1\|WP_003721305.1\|602767_604456_+\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	cas8b2	cd09754_cas8b2_CAS-I-B	gnl\|CDD\|187884
NZ_CP045970.1\|WP_003721291.1\|589024_589675_+\|ribulose-phosphate-3-epimerase	unknown	unknown	gnl\|CDD\|223114
NZ_CP045970.1\|WP_003721292.1\|589671_590718_+\|galactitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|176198
NZ_CP045970.1\|WP_003721293.1\|590733_591027_+\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99908
NZ_CP045970.1\|WP_003721304.1\|602029_602752_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam01881_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
NZ_CP045970.1\|WP_003721290.1\|588615_589014_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045970.1\|WP_003721294.1\|591041_592313_+\|PTS-galactitol-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226298
NZ_CP045970.1\|WP_003721295.1\|592452_593388_+\|ribose-phosphate-pyrophosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_CP045970.1\|WP_003721302.1\|599311_600742_-\|CapA-family-protein	unknown	unknown	gnl\|CDD\|225399
NZ_CP045970.1\|WP_003721301.1\|598833_599265_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP045970.1\|WP_003721299.1\|596057_596516_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378956
NZ_CP045970.1\|WP_003721298.1\|595691_596051_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131113
NZ_CP045970.1\|WP_003721288.1\|587501_588104_+\|SIS-domain-containing-protein	unknown	unknown	gnl\|CDD\|223865
NZ_CP045970.1\|WP_003721297.1\|594986_595667_+\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|153212
NZ_CP045970.1\|WP_003721287.1\|585437_587498_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP045970.1\|WP_003721303.1\|600862_601678_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NZ_CP045970.1\|WP_003721300.1\|596897_598733_+\|lmo0514-family-class-1-internalin	unknown	unknown	gnl\|CDD\|380190
NZ_CP045970.1\|WP_003721286.1\|584678_585329_+\|transaldolase	unknown	unknown	gnl\|CDD\|223254
NZ_CP045970.1\|WP_009930754.1\|594300_594879_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045970.1\|WP_003721289.1\|588131_588599_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|238129

Protein	Function_ID	Function_description	E-value
NZ_CP045970.1\|WP_003721305.1\|602767_604456_+\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	gnl\|CDD\|187884	cd09754, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as CXXC_CXXC family.	5.75294e-26
NZ_CP045970.1\|WP_003721291.1\|589024_589675_+\|ribulose-phosphate-3-epimerase	gnl\|CDD\|223114	COG0036, Rpe, Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism].	4.74405e-108
NZ_CP045970.1\|WP_003721293.1\|590733_591027_+\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|99908	cd05566, PTS_IIB_galactitol, PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain that are expressed on three distinct polypeptide chains, in contrast to other PTS sugar transporters. The three genes encoding these subunits (gatA, gatB, and gatC) comprise the gatCBA operon. Galactitol PTS permease takes up exogenous galactitol, releasing the phosphate ester into the cytoplasm in preparation for oxidation and further metabolism via a modified glycolytic pathway called the tagatose-6-phosphate glycolytic pathway. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include galactitol, chitobiose/lichenan, ascorbate, lactose, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	3.06007e-27
NZ_CP045970.1\|WP_003721304.1\|602029_602752_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	2.75155e-33
NZ_CP045970.1\|WP_003721300.1\|596897_598733_+\|lmo0514-family-class-1-internalin	gnl\|CDD\|380190	NF033186, internalin_K, class 1 internalin InlK. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface-anchored proteins with an N-terminal signal peptide, leucine-rich repeats, and a C-terminal LPXTG processing and cell surface anchoring site. Members of this family are internalin K (InlK), a virulence factor. See articles PMID:17764999. for a general discussion of internalins, and PMID:21829365, PMID:22082958, and PMID:23958637 for more information about internalin K.	1.95498e-119
NZ_CP045970.1\|WP_003721299.1\|596057_596516_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|378956	pfam12802, MarR_2, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.	8.31646e-13
NZ_CP045970.1\|WP_003721298.1\|595691_596051_-\|hypothetical-protein	gnl\|CDD\|131113	TIGR02058, lin0512_fam, conserved hypothetical protein. This family consists of few members, broadly distributed. It occurs so far in several Firmicutes (twice in Oceanobacillus), one Cyanobacterium, one alpha Proteobacterium, and (with a long prefix) in plants. The function is unknown. The alignment includes a perfectly conserved motif GxGxDxHG near the N-terminus. [Hypothetical proteins, Conserved].	5.62162e-67
NZ_CP045970.1\|WP_003721295.1\|592452_593388_+\|ribose-phosphate-pyrophosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	2.38027e-153
NZ_CP045970.1\|WP_003721302.1\|599311_600742_-\|CapA-family-protein	gnl\|CDD\|225399	COG2843, PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) [Cell envelope biogenesis, outer membrane].	1.43469e-99
NZ_CP045970.1\|WP_003721301.1\|598833_599265_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	4.03126e-27
NZ_CP045970.1\|WP_003721288.1\|587501_588104_+\|SIS-domain-containing-protein	gnl\|CDD\|223865	COG0794, GutQ, Predicted sugar phosphate isomerase involved in capsule formation [Cell envelope biogenesis, outer membrane].	1.67992e-75
NZ_CP045970.1\|WP_003721297.1\|594986_595667_+\|type-1-glutamine-amidotransferase	gnl\|CDD\|153212	cd01741, GATase1_1, Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. This group contains a subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. GATase activity catalyses the transfer of ammonia from the amide side chain of glutamine to an acceptor substrate. Glutamine amidotransferases (GATase) includes the triad family of amidotransferases which have a conserved Cys-His-Glu catalytic triad in the glutaminase active site. In this subgroup this triad is conserved. GATase activity can be found in a range of biosynthetic enzymes, including: glutamine amidotransferase, formylglycinamide ribonucleotide, GMP synthetase , anthranilate synthase component II, glutamine-dependent carbamoyl phosphate synthase, cytidine triphosphate synthetase, gamma-glutamyl hydrolase, imidazole glycerol phosphate synthase and, cobyric acid synthase. Glutamine amidotransferase (GATase) domains can occur either as single polypeptides, as in glutamine amidotransferases, or as domains in a much larger multifunctional synthase protein, such as CPSase.	7.71833e-60
NZ_CP045970.1\|WP_003721287.1\|585437_587498_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	2.1337e-80
NZ_CP045970.1\|WP_003721303.1\|600862_601678_-\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	5.01016e-50
NZ_CP045970.1\|WP_003721294.1\|591041_592313_+\|PTS-galactitol-transporter-subunit-IIC	gnl\|CDD\|226298	COG3775, GatC, Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism].	7.01085e-178
NZ_CP045970.1\|WP_003721286.1\|584678_585329_+\|transaldolase	gnl\|CDD\|223254	COG0176, MipB, Transaldolase [Carbohydrate transport and metabolism].	1.40072e-62
NZ_CP045970.1\|WP_003721292.1\|589671_590718_+\|galactitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|176198	cd08236, sugar_DH, NAD(P)-dependent sugar dehydrogenases. This group contains proteins identified as sorbitol dehydrogenases and other sugar dehydrogenases of the medium-chain dehydrogenase/reductase family (MDR), which includes zinc-dependent alcohol dehydrogenase and related proteins. Sorbitol and aldose reductase are NAD(+) binding proteins of the polyol pathway, which interconverts glucose and fructose. Sorbitol dehydrogenase is tetrameric and has a single catalytic zinc per subunit. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Related proteins include threonine dehydrogenase, formaldehyde dehydrogenase, and butanediol dehydrogenase. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Horse liver alcohol dehydrogenase is a dimeric enzyme and each subunit has two domains. The NAD binding domain is in a Rossmann fold and the catalytic domain contains a zinc ion to which substrates bind. There is a cleft between the domains that closes upon formation of the ternary complex.	0
NZ_CP045970.1\|WP_003721289.1\|588131_588599_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	3.45565e-37

>NZ_CP045970.1|WP_003721295.1|592452_593388_+|ribose-phosphate-pyrophosphokinase
MAGKMKLFSVTSERPLATKIADYLDIPLCEVELQKFSDGEVKINIEESIRGTNAYVVQSMNSNVNERLMELLIMVDALKRASVHSINIIMPYYGYARQDRKARSREPITAKLMANLIQRAGANRLITVDLHAAQIQGFFNIPIDHLSAIPLIGDYLIENYGEKDVVVVAPDHSGVVRARRIADRLNAPIAILNRKPRPHEDEIMSVIGDVKGKVAIVVDDIIDTGVRATTSADILLEKGAVEVIACATHSVMAGNATERLQNSSIKEVITSDSIDLPEDKQFDKLTTISIGRILGRAIEGVQENRSLHPLF
>NZ_CP045970.1|WP_003721294.1|591041_592313_+|PTS-galactitol-transporter-subunit-IIC
MDIILDFFKYIIGLGVTVMMPIIITILGVIFRKKISVAFKAGLTVGVGFVGLGVITSLMLTTITPVTKALVENYNFKLTATDIGWGVGSSLAWGTEVVPFVFVAIIATNILMIAFKWTKTMDVDIWNYWQPLFIASALYLTTGSMIIAVLSSIINMAIIFKIADWTQKDVEDVLGLEGISLPQIQTTGWALVGYPMNWLLGKIPGVRKINWSTEKVQSRLGIFGEPMLMGLIIGGGLAAIAQMPLSQVLQTGVTIAASLVLIPRMVSLLMDGLTVISEAAHEFMEKRFPGRELFIGLDSAVGIGHPFVLSLGLLMIPITLILAFILPGNKVLPLADLTALPFYMIFAIVPSKGNLFRGIFTGIVIVIITLYLSGAAAPLMTELAGQIGYNIPKDAVEVTSLAVGTQWYTWIVYYGLHWFGGIL
>NZ_CP045970.1|WP_003721293.1|590733_591027_+|PTS-sugar-transporter-subunit-IIB
MKKKRIYVCCGTGIATSTVISKKVRAVLDEKRIPYEISQCTVQEVASKVSTSKPDIIVSSTTVTGDVGDVPVVIGRSFLTGLKKQETIDEILAILQD
>NZ_CP045970.1|WP_003721292.1|589671_590718_+|galactitol-1-phosphate-5-dehydrogenase
MKALKLYGKRDLRYEEADMPTIEEPDDVILKVKTVGICGSDISRYSKLGPYVPGMVWGHEFSGEVIEVGSEVTDIEIGDRAAGCPALYCGECEYCKKGEFARCRKLTVIGARHPGAYAEYIKLPAENVVKIPDELDYEAAALVEPSAVVVHGFYHTKLQAGDDVVVVGSGNIGLLAIQWAKVFGARRVIAIDVDDKKLALAKEVGADVVINSLKEDPLEVVAAHTDGLNADLVVEAAGSPITSAQVFAYAKKGGGVVFLGIPYADVTIERFYFEKIVRSELTVWGSWNAISAPFPGKEWQTTIHFLANKQINIEPMITHRLSLAEGPEVFERIYERNEFFGKVLFFPE
>NZ_CP045970.1|WP_003721291.1|589024_589675_+|ribulose-phosphate-3-epimerase
MAKIVPSVFGADIGRINEQLQVLEKNDIDLLHVDMMDGSFVPNIAFGPDQIKMMKKGTKLQFDVHMMVYEPDRYIPRLVEAGAHMITVHQEATTHLHRTIQLIKSYGVRAGVVLNPGTPPSTLEYVLDDIDCILLMTVNPGLGGQKFFQSSLEKIRKTKAYIGNRPIQIEVDGGVNDELAKECTLAGADLIVVGSYLFEGDIEANLEKLAKGVLTE
>NZ_CP045970.1|WP_003721290.1|588615_589014_+|hypothetical-protein
MGSFFASFVDWLIGSPGRFVVNLIEDNMLIFMVVVMIYATTILYAKWTLAYYLPKKMSQLAEMKTWELDELYAAWQTEKKALPWYILVPSRNEFWVKSARNAPESTKLLHFSQQKLKLSDKEKLQKIIEIQS
>NZ_CP045970.1|WP_003721289.1|588131_588599_+|PTS-sugar-transporter-subunit-IIA
MDVLEYFKEEMVRFSNEQDKEKLLTEMAEQLCEVGAVKPSYKDAVIKREKVFPTGLLTAHAGVAIPHTDSEHVIRPVVAVRILKKPVSFIEMASDNEAIDVRIVFMMALRSADEQLDMLQTLIQLIQDEEVMTTLLKAQETGDVLSAIEHFSKNN
>NZ_CP045970.1|WP_003721288.1|587501_588104_+|SIS-domain-containing-protein
MDKQAILNNIHQTWQEEANAISRLPEVTSEEALVKTVETIAECTGKIVVAGCGTSGVAAKKLVHSFNCIERPAVFLTPSDAVHGTLGVLQKEDILILISKGGNTGELLNLIPACKTKGSTLIGVTENPDSVIAKEADIFFPVSVSKEPDPFNMLATASTMAVIASFDAVIVCLMTYMNYTKEQFSVIHPGGAVGNKLLNK
>NZ_CP045970.1|WP_003721287.1|585437_587498_+|BglG-family-transcription-antiterminator
MYLDNRSKTLFQEVIKNPNITNKQLEVKYKLSRYQISYSFQKVNEWLKWKNYPEVKRSKNGRFILEPELTALFSEKETRDPSVEYLPSENERANLILLMLLTSKEELSLAHFTTKIQVSKNTILRDLKVAQKLLPKETTVTYSRASGYQLAGSEWELRKVLTQVVSSVKEMFRGEHYFLSYSGIEKVQLMEIRRTLEEAEAMMQIKFTYEQIELLPYLLSVMFLRIRDRRLIDTAFHIDEKSLSDTREYHITDILLEKTGPVPEQERLFITLQLLTTNIFSGEILTEKLTEDLEKVVLTCLDLFEKKALVSLKNKHILIEKLLLHLKPAYYRIKYQMNLEDTLYEKFNQEFEALNFIVKEAFDPLAKFIGREIPAGEIFFISLFIGSDMIPQNDIYHKQKRAIVLCPSGVTFSKIMENILVKLFPEIHFYPTISVREYAFFKAEVDIVFSSIPLKDGENVFVVQPFMNDIEKTQLRQHVLQNLFGMGNQLTSIDKIMEVVERNADINDSNAIRDGIIDILSANTATDENKRVKKVYLHDLITEDNIMICEDVKNYQEAIRLASQPLLLQQAITANYVKTMIDNHKFHDPYIIIGEDIAIPHAMPNAGVNRLAMSLLVVKNGVYFSETEQVHFVIVIAPVDKEQHIEALYQIVHLAENHQILDDLLENVTKEKIMQTINQLVIREDE
>NZ_CP045970.1|WP_003721286.1|584678_585329_+|transaldolase
MHLDSANLDDVKKIQASSIFKGITTNPSILVKEKCNRQTAINRILELTDKQVFVQTVGFTYEEILADARMLLTMFGKDKIAIKIPAHEAGTNVIDTLKKEDKTIQILGTAIYSADQAITAALAGADFVAPYVNRMSAANIDPFKEISQMRHFFDKKALKTQIMAASFKHSGQVMQAYESGADTVTIPYEIYSQMTNKVLAVEAIRVFNEDAVLYEK
>NZ_CP045970.1|WP_009930754.1|594300_594879_+|hypothetical-protein
MKKILVPILLLATILASCSSPNEKITKDTKISKTITIRADYKVPKDIKELEDDSANIVKVKFLQNKTIGKDGSTISEIEILTSYKGNLEKGSKVDISEPWYLSDGKYVAVENYIALDKEQEYTIFLGEKDKDTYPLSSLGYGKFGGSLKEDQAVLADFNILGEVQKFDFISENTEEVKNYQLIKEQVAGKYK
>NZ_CP045970.1|WP_003721297.1|594986_595667_+|type-1-glutamine-amidotransferase
MIIDVLQHVPHEGPGLIANWARENQHQLKIHSLFEENAHVPNDSDFLIVLGGPMGINDTAEFPWLKDERKLIKRLSEQHKPVFGVCLGAQQIAATFGSEITVNKEKEVGWFPVKRTSDKLLFFPESLNVFHWHQDTFALPTGSTRLFASEGCLNQAFLYGENIIGLQFHFEMEKAGIETILRIDEAFITPGKYVQSVEVMREKDVPEDNKQMLEAILDYLINPKTI
>NZ_CP045970.1|WP_003721298.1|595691_596051_-|hypothetical-protein
MEQILFIQTGFGVDVHGQNITKAAERAVRNAIFTNSMPGIQGLLPDGDLQNMVVNIKLALPCDADQLDEDTIRAIIPYGTVTIEKMAGGMMTTSGIFLEDKEDKNDLMYIVNASVETGY
>NZ_CP045970.1|WP_003721299.1|596057_596516_-|MarR-family-transcriptional-regulator
MNNEQNMNQQIALFYFGYKAFTETADLIIAKHSLKRLHHRILFFTARMPGLTINELLTFLEISKQALHQPLAELKERELLTIEQGRRDKRQRCIFLTSAGKELENELGDAQRKQMSEIFTNSADTDGMHFTEVMEGYAKNRPGAAFIKDFKE
>NZ_CP045970.1|WP_003721300.1|596897_598733_+|lmo0514-family-class-1-internalin
MKKALKLFLAMICMFIMIYPSTAAHAEETNIVNIPDANLKTYLNGLLKQASDAPITKTQMNTIQTVTLSGSTYTDLTGLEEAGNLVTLSLNNTNIQTLEPIKNQTSLTYLTVGGDNVKDSLFVDLNGLVNLQSLSINGSEVTHNVFKTFNKLPKLTYLYAQNSMKITDISALASLPALTTLFLQFDGIDDFRPLNDFESFKNGNLKALAAFGQNTGRTNPRITLKSGKLDYNETNQTLYLPFSMMPKPLTSFDGTVAPFSKSTSASNTYLGFNDVALPSARLSITEDGITVSGVTKEEFDNLDEIEYNARYDFPTGSYPTPPSMTSYTISSGTYDQYFDISHTLDLTADESFDYNQYDTTSEEQFLKDVHAETDDGTAVKSDFDQVVKLDVPGEYTVTLNAENAAGLKATPVTVKVTVHEKPVITSDSQISYKKETTKSVDEFLKEIHGSVTGNAVLTSDFDKVVDLNTPGEYTVTLNAINDRGQKADPVTVVVTVTTSDSGHVNPVPPTPEVKPTPQEETDQTIIPEPQSETTEDSVKEDQAKDGQAKSEEKADKTSLTTKENKVEKSEKTNQPKTKALPQTGDTNKTALPIAGVMLSLAALLIFRKSKS
>NZ_CP045970.1|WP_003721301.1|598833_599265_+|universal-stress-protein
MEKYHRILVAVDGSEPAKLAFEKGLELALKLDGVLGIASIVDLRAFSPNVSYDGSLEEKAELELKTSVNEYAEKARTAGVKQVETFVAKGNPKILLSTDIPAEFQADLIICGATGMNRVEKLVLGSVSSYIMAHAICDTLIAR
>NZ_CP045970.1|WP_003721302.1|599311_600742_-|CapA-family-protein
MKRRTYVIITGLVLIFIAGAFWITNSTNQSDQKATQTEPLKKTSPANVKTISSEAKKTLNSLASSGADKASISDLNQLIKELKSYPVEKNDSGAYLQNLTACLEAVKSYTTGKADEKTLGKVYPAFLASEQKLSAIEKTNQYDWFYAAAATNQQGLKEKGVVTLTMVGDNSFGTYPETPEHLKFDNVFQKNNGNNTYVYKNCLPWFKSDDYTIINAESAFTNATKAENKKWRIKSDPAHVAFLPASGVEAANLANNHTMDYFQVGYDDTLKAFKENNIPVFNTDAPLETTIKGMKTVLLGYDCRMSQQSPAYLERIVKDVKKYKKEDTLVIVNMHWGVEYRETPTDYQTQFGHAILDAGADIIMGSHPHRLESVEKYKDKYIVYSMGDFAFGADPTLLSRMTSMFQLRFTKEDNKIVLKDISIVPTYENSDGSTTENNYQPLPVFGDDAKKIVDELNRISKPIKGGVTEYTYFDPF
>NZ_CP045970.1|WP_003721303.1|600862_601678_-|histidine-phosphatase-family-protein
MKKNIFKLLMALCAVLLIAGCGNSTSADKKETKETKEDGTVTFYVVRHGKTMLNTTDRVQGWSDAVLTPAGEEVVKSAGKGLKDVDFSAAYSSDSGRAIQTANLILKESDKSADKEVQTDPRFREFNFGSYEGDLNENMWTDIAKSQGKTLEEWQKAGLSPKDFANSVAALDKTRVKEGENWPAEDYATIQARLKEGLTDVAKKESKNGDSNVLLVSHGLSIGALLDTIEPGYKLPAEGIKNASVTKITYKDGKFTIGDVNDLSYVEKGSK
>NZ_CP045970.1|WP_003721304.1|602029_602752_+|CRISPR-associated-endoribonuclease-Cas6
MRLKINCDFDSKIISKDFQSKVVSLFKAGIMKSSPERYENLFGGNKHKQYTFSVYLPKPQNKGAEIQLNEANCIINFSTGDAETGIIFYNALMSLRGSKVLFGAGNHITVKNIQIVPEKKIIGKRTILRTLSPVVSRDHNRETFKNWFYSFEDEEFEPTLKRNMLPYLMDAFGEQARYDLEKLKITPISMKKVVVYCHEIHIESSVGIFELEAEAYLQKYLVENGIGTMTGSGFGMIEQF
>NZ_CP045970.1|WP_003721305.1|602767_604456_+|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1
MRTEIEVRANDWLINAGLTGFLNIVGKENVRIDGQAIYFTADLLEDFETKYFNFFIQEYKETLSWYKIVSYKETMEQFRIDEFASFDEVALGNLNKYMKDVVKFYLKKANYIKVFPLIDPSANVTKWLEKLNTINLTKKQKWDEVKADIIEEVKQTYTQLDLIIDFCASEKGLQYLGAKNLIYSVINKGWSGVSFLLKQTKFIDPYLDYKTSFLDPVIDYLDTDLSKAKYNCFNCNQPIKNLKLDLSFMNDVGFDTARKTAHVWDFNNDVATCPICRLIYSCVPAGFTYVYGEGMFVNDSYGVEELHRVNERMRNSILRFNKDGINSTNTYRALVESITMEHENNRRYELADIQLVRYENEHYRFNLLSKKMLHIVNDSKGILKSLIRCGYKEGNLNVNLYKEVIQHLMNNENLFTLIHKLIYYKQTSVNGLYYNMGHVSGILDINTKFLKEMEVMTNISQNQLWFVQNCGKEFKEGYVKKKSENKISGITYKLLNSLKVNDKDGFMDTLLNSYSYLSMPIPDVFIKMFSNNEAFKSVGYAFMLGVGGEKTKKEDGGNTDEK

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Crispr_ID: NZ_CP045970_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045970_3

609105-611012

Unclear

I-A

Consensus_repeat	Method
GTTTTAACTACTTATTATGAAATGTAAAT	PILER-CR
GTTTTAACTACTTATTATGAAATGTAAAT	CRISPRCasFinder
GTTTTAACTACTTATTATGAAATGTAAAT	CRT

29 spacers

cas2,cas3,cas5,cas7,cas8b2,cas6

The CRISPR arrays of NZ_CP045970_3

>merge|NZ_CP045970|3|609105-611012|PILER-CR,CRISPRCasFinder,CRT
GTTTTAACTACTTATTATGAAATGTAAATAAAGACCTTCGATTTCATTCTCACTTTCCAGTTAATGTTTTAACTACTTATTATGAAATGTAAATTTTTTTGTAGCGGAGGTGTACAATGCCGAAAGTGACGTTTTAACTACTTATTATGAAATGTAAATGCTGGTAAATTTGGCGGAACTAATCGTACTGAAATAGTTTTAACTACTTATTATGAAATGTAAATACATATTAGCCCTTATATAGAAGCCCCGCCCCTACCAGTTTTAACTACTTATTATGAAATGTAAATTATAGTCCCCATATCCATCTGCTATTATCCTCCACGTTTTAACTACTTATTATGAAATGTAAATCGCTTCACGTTGGTTTTTCGTAGCCCAATTGCTAAAGTTTTAACTACTTATTATGAAATGTAAATACGTTGGACAACGAGGTGAGTATGATATGACTCAAATGTTTTAACTACTTATTATGAAATGTAAATGCGGAATGCGAAGTTGTTATATATAACTTATCTCGCGTTTTAACTACTTATTATGAAATGTAAATTCTTAAATGGTGTTTGCACATGTTAAGGGAGTCATGGTTTTAACTACTTATTATGAAATGTAAATGTGCATATCTCCTATATTCATGGCTGTATATGTGTGTTTTAACTACTTATTATGAAATGTAAATCTGGTTACTCAACTGGCGACAGTAATACACCTCAATGTTTTAACTACTTATTATGAAATGTAAATTTTGGATAGGTTGTTTCTGATAAATAGGTTCACGGTTTTAACTACTTATTATGAAATGTAAATAAGTCTACTTGGATTTAGCTCTACACCTGCAACATGAGTTTTAACTACTTATTATGAAATGTAAATAGAAAAAAAACATCTTTCCAATTTGTTGTTTTGCGTTTTAACTACTTATTATGAAATGTAAATAGAAGCGTTAGCGGCATTGTTCGAAAGTAATTTAGTTTTAACTACTTATTATGAAATGTAAATTATAAAATATTGCCCAATGTGCGGAAGGAGTTTGGAGTTTTAACTACTTATTATGAAATGTAAATCTCATAAGGATTTCGAGGCGGGTTAAACGACATGTAGTTTTAACTACTTATTATGAAATGTAAATGCTTTTTTCAACAATTTTATCACCAGATGTCATTAGTTTTAACTACTTATTATGAAATGTAAATTGAGCAGTGTCACCTGTTTCCGTATCTGCTTTTTTCGTTTTAACTACTTATTATGAAATGTAAATAAGAAATCCGGGAAGTTTTGTTCTACAGAGCGAACGGGTTTTAACTACTTATTATGAAATGTAAATGTCAATAACTAGACGAGCTAACGTTTGTCGCTGTTTGTTTTAACTACTTATTATGAAATGTAAATTGTTATCTCCTGTGATGTAAAATAACCCTTCTATCGTTTTAACTACTTATTATGAAATGTAAATTAATACAAAATATTCATAACTCCTACATCATTATATAGTTTTAACTACTTATTATGAAATGTAAATTTGCAAACCTAACTTATCTTTGTTTTTTTGCTTTTCGTTTTAACTACTTATTATGAAATGTAAATACGTTTGCGGTAGTTTTACCGGGCACGGTCAAATATGTTTTAACTACTTATTATGAAATGTAAATCAAAACAGAGAACGCGTGTTCATTATCGGACATCTTAGTTTTAACTACTTATTATGAAATGTAAATTTTTGAAATATGAGGACTTAGAAAATGAAAAAAATGTTTTAACTACTTATTATGAAATGTAAATAAAAACTATGCAATTAGCAAAGTGATTTTATGTAATTGTTTTAACTACTTATTATGAAATATAAATTAACGAGCCAATTAAACCATCTTCTTCTAGTAATGTTTTAACTACTTATTATGAAATCATAAA

>NZ_CP045970|3|2|609105-610949|PILER-CR
GTTTTAACTACTTATTATGAAATGTAAAT	AAAGACCTTCGATTTCATTCTCACTTTCCAGTTAAT
GTTTTAACTACTTATTATGAAATGTAAAT	TTTTTTGTAGCGGAGGTGTACAATGCCGAAAGTGAC
GTTTTAACTACTTATTATGAAATGTAAAT	GCTGGTAAATTTGGCGGAACTAATCGTACTGAAATA
GTTTTAACTACTTATTATGAAATGTAAAT	ACATATTAGCCCTTATATAGAAGCCCCGCCCCTACCA
GTTTTAACTACTTATTATGAAATGTAAAT	TATAGTCCCCATATCCATCTGCTATTATCCTCCAC
GTTTTAACTACTTATTATGAAATGTAAAT	CGCTTCACGTTGGTTTTTCGTAGCCCAATTGCTAAA
GTTTTAACTACTTATTATGAAATGTAAAT	ACGTTGGACAACGAGGTGAGTATGATATGACTCAAAT
GTTTTAACTACTTATTATGAAATGTAAAT	GCGGAATGCGAAGTTGTTATATATAACTTATCTCGC
GTTTTAACTACTTATTATGAAATGTAAAT	TCTTAAATGGTGTTTGCACATGTTAAGGGAGTCATG
GTTTTAACTACTTATTATGAAATGTAAAT	GTGCATATCTCCTATATTCATGGCTGTATATGTGT
GTTTTAACTACTTATTATGAAATGTAAAT	CTGGTTACTCAACTGGCGACAGTAATACACCTCAAT
GTTTTAACTACTTATTATGAAATGTAAAT	TTTGGATAGGTTGTTTCTGATAAATAGGTTCACG
GTTTTAACTACTTATTATGAAATGTAAAT	AAGTCTACTTGGATTTAGCTCTACACCTGCAACATGA
GTTTTAACTACTTATTATGAAATGTAAAT	AGAAAAAAAACATCTTTCCAATTTGTTGTTTTGC
GTTTTAACTACTTATTATGAAATGTAAAT	AGAAGCGTTAGCGGCATTGTTCGAAAGTAATTTA
GTTTTAACTACTTATTATGAAATGTAAAT	TATAAAATATTGCCCAATGTGCGGAAGGAGTTTGGA
GTTTTAACTACTTATTATGAAATGTAAAT	CTCATAAGGATTTCGAGGCGGGTTAAACGACATGTA
GTTTTAACTACTTATTATGAAATGTAAAT	GCTTTTTTCAACAATTTTATCACCAGATGTCATTA
GTTTTAACTACTTATTATGAAATGTAAAT	TGAGCAGTGTCACCTGTTTCCGTATCTGCTTTTTTC
GTTTTAACTACTTATTATGAAATGTAAAT	AAGAAATCCGGGAAGTTTTGTTCTACAGAGCGAACGG
GTTTTAACTACTTATTATGAAATGTAAAT	GTCAATAACTAGACGAGCTAACGTTTGTCGCTGTTT
GTTTTAACTACTTATTATGAAATGTAAAT	TGTTATCTCCTGTGATGTAAAATAACCCTTCTATC
GTTTTAACTACTTATTATGAAATGTAAAT	TAATACAAAATATTCATAACTCCTACATCATTATATA
GTTTTAACTACTTATTATGAAATGTAAAT	TTGCAAACCTAACTTATCTTTGTTTTTTTGCTTTTC
GTTTTAACTACTTATTATGAAATGTAAAT	ACGTTTGCGGTAGTTTTACCGGGCACGGTCAAATAT
GTTTTAACTACTTATTATGAAATGTAAAT	CAAAACAGAGAACGCGTGTTCATTATCGGACATCTTA
GTTTTAACTACTTATTATGAAATGTAAAT	TTTTGAAATATGAGGACTTAGAAAATGAAAAAAAT
GTTTTAACTACTTATTATGAAATGTAAAT	AAAAACTATGCAATTAGCAAAGTGATTTTATGTAATT
GTTTTAACTACTTATTATGAAATATAAAT

>NZ_CP045970|3|2|609105-611012|CRISPRCasFinder
GTTTTAACTACTTATTATGAAATGTAAAT	AAAGACCTTCGATTTCATTCTCACTTTCCAGTTAAT
GTTTTAACTACTTATTATGAAATGTAAAT	TTTTTTGTAGCGGAGGTGTACAATGCCGAAAGTGAC
GTTTTAACTACTTATTATGAAATGTAAAT	GCTGGTAAATTTGGCGGAACTAATCGTACTGAAATA
GTTTTAACTACTTATTATGAAATGTAAAT	ACATATTAGCCCTTATATAGAAGCCCCGCCCCTACCA
GTTTTAACTACTTATTATGAAATGTAAAT	TATAGTCCCCATATCCATCTGCTATTATCCTCCAC
GTTTTAACTACTTATTATGAAATGTAAAT	CGCTTCACGTTGGTTTTTCGTAGCCCAATTGCTAAA
GTTTTAACTACTTATTATGAAATGTAAAT	ACGTTGGACAACGAGGTGAGTATGATATGACTCAAAT
GTTTTAACTACTTATTATGAAATGTAAAT	GCGGAATGCGAAGTTGTTATATATAACTTATCTCGC
GTTTTAACTACTTATTATGAAATGTAAAT	TCTTAAATGGTGTTTGCACATGTTAAGGGAGTCATG
GTTTTAACTACTTATTATGAAATGTAAAT	GTGCATATCTCCTATATTCATGGCTGTATATGTGT
GTTTTAACTACTTATTATGAAATGTAAAT	CTGGTTACTCAACTGGCGACAGTAATACACCTCAAT
GTTTTAACTACTTATTATGAAATGTAAAT	TTTGGATAGGTTGTTTCTGATAAATAGGTTCACG
GTTTTAACTACTTATTATGAAATGTAAAT	AAGTCTACTTGGATTTAGCTCTACACCTGCAACATGA
GTTTTAACTACTTATTATGAAATGTAAAT	AGAAAAAAAACATCTTTCCAATTTGTTGTTTTGC
GTTTTAACTACTTATTATGAAATGTAAAT	AGAAGCGTTAGCGGCATTGTTCGAAAGTAATTTA
GTTTTAACTACTTATTATGAAATGTAAAT	TATAAAATATTGCCCAATGTGCGGAAGGAGTTTGGA
GTTTTAACTACTTATTATGAAATGTAAAT	CTCATAAGGATTTCGAGGCGGGTTAAACGACATGTA
GTTTTAACTACTTATTATGAAATGTAAAT	GCTTTTTTCAACAATTTTATCACCAGATGTCATTA
GTTTTAACTACTTATTATGAAATGTAAAT	TGAGCAGTGTCACCTGTTTCCGTATCTGCTTTTTTC
GTTTTAACTACTTATTATGAAATGTAAAT	AAGAAATCCGGGAAGTTTTGTTCTACAGAGCGAACGG
GTTTTAACTACTTATTATGAAATGTAAAT	GTCAATAACTAGACGAGCTAACGTTTGTCGCTGTTT
GTTTTAACTACTTATTATGAAATGTAAAT	TGTTATCTCCTGTGATGTAAAATAACCCTTCTATC
GTTTTAACTACTTATTATGAAATGTAAAT	TAATACAAAATATTCATAACTCCTACATCATTATATA
GTTTTAACTACTTATTATGAAATGTAAAT	TTGCAAACCTAACTTATCTTTGTTTTTTTGCTTTTC
GTTTTAACTACTTATTATGAAATGTAAAT	ACGTTTGCGGTAGTTTTACCGGGCACGGTCAAATAT
GTTTTAACTACTTATTATGAAATGTAAAT	CAAAACAGAGAACGCGTGTTCATTATCGGACATCTTA
GTTTTAACTACTTATTATGAAATGTAAAT	TTTTGAAATATGAGGACTTAGAAAATGAAAAAAAT
GTTTTAACTACTTATTATGAAATGTAAAT	AAAAACTATGCAATTAGCAAAGTGATTTTATGTAATT
GTTTTAACTACTTATTATGAAATATAAAT	TAACGAGCCAATTAAACCATCTTCTTCTAGTAAT
GTTTTAACTACTTATTATGAAATCATAAA

>NZ_CP045970|3|3|609105-611012|CRT
GTTTTAACTACTTATTATGAAATGTAAAT	AAAGACCTTCGATTTCATTCTCACTTTCCAGTTAAT
GTTTTAACTACTTATTATGAAATGTAAAT	TTTTTTGTAGCGGAGGTGTACAATGCCGAAAGTGAC
GTTTTAACTACTTATTATGAAATGTAAAT	GCTGGTAAATTTGGCGGAACTAATCGTACTGAAATA
GTTTTAACTACTTATTATGAAATGTAAAT	ACATATTAGCCCTTATATAGAAGCCCCGCCCCTACCA
GTTTTAACTACTTATTATGAAATGTAAAT	TATAGTCCCCATATCCATCTGCTATTATCCTCCAC
GTTTTAACTACTTATTATGAAATGTAAAT	CGCTTCACGTTGGTTTTTCGTAGCCCAATTGCTAAA
GTTTTAACTACTTATTATGAAATGTAAAT	ACGTTGGACAACGAGGTGAGTATGATATGACTCAAAT
GTTTTAACTACTTATTATGAAATGTAAAT	GCGGAATGCGAAGTTGTTATATATAACTTATCTCGC
GTTTTAACTACTTATTATGAAATGTAAAT	TCTTAAATGGTGTTTGCACATGTTAAGGGAGTCATG
GTTTTAACTACTTATTATGAAATGTAAAT	GTGCATATCTCCTATATTCATGGCTGTATATGTGT
GTTTTAACTACTTATTATGAAATGTAAAT	CTGGTTACTCAACTGGCGACAGTAATACACCTCAAT
GTTTTAACTACTTATTATGAAATGTAAAT	TTTGGATAGGTTGTTTCTGATAAATAGGTTCACG
GTTTTAACTACTTATTATGAAATGTAAAT	AAGTCTACTTGGATTTAGCTCTACACCTGCAACATGA
GTTTTAACTACTTATTATGAAATGTAAAT	AGAAAAAAAACATCTTTCCAATTTGTTGTTTTGC
GTTTTAACTACTTATTATGAAATGTAAAT	AGAAGCGTTAGCGGCATTGTTCGAAAGTAATTTA
GTTTTAACTACTTATTATGAAATGTAAAT	TATAAAATATTGCCCAATGTGCGGAAGGAGTTTGGA
GTTTTAACTACTTATTATGAAATGTAAAT	CTCATAAGGATTTCGAGGCGGGTTAAACGACATGTA
GTTTTAACTACTTATTATGAAATGTAAAT	GCTTTTTTCAACAATTTTATCACCAGATGTCATTA
GTTTTAACTACTTATTATGAAATGTAAAT	TGAGCAGTGTCACCTGTTTCCGTATCTGCTTTTTTC
GTTTTAACTACTTATTATGAAATGTAAAT	AAGAAATCCGGGAAGTTTTGTTCTACAGAGCGAACGG
GTTTTAACTACTTATTATGAAATGTAAAT	GTCAATAACTAGACGAGCTAACGTTTGTCGCTGTTT
GTTTTAACTACTTATTATGAAATGTAAAT	TGTTATCTCCTGTGATGTAAAATAACCCTTCTATC
GTTTTAACTACTTATTATGAAATGTAAAT	TAATACAAAATATTCATAACTCCTACATCATTATATA
GTTTTAACTACTTATTATGAAATGTAAAT	TTGCAAACCTAACTTATCTTTGTTTTTTTGCTTTTC
GTTTTAACTACTTATTATGAAATGTAAAT	ACGTTTGCGGTAGTTTTACCGGGCACGGTCAAATAT
GTTTTAACTACTTATTATGAAATGTAAAT	CAAAACAGAGAACGCGTGTTCATTATCGGACATCTTA
GTTTTAACTACTTATTATGAAATGTAAAT	TTTTGAAATATGAGGACTTAGAAAATGAAAAAAAT
GTTTTAACTACTTATTATGAAATGTAAAT	AAAAACTATGCAATTAGCAAAGTGATTTTATGTAATT
GTTTTAACTACTTATTATGAAATATAAAT	TAACGAGCCAATTAAACCATCTTCTTCTAGTAAT
GTTTTAACTACTTATTATGAAATCATAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045970.1\|WP_003721305.1\|602767_604456_+\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	cas8b2	cd09754_cas8b2_CAS-I-B	gnl\|CDD\|187884
NZ_CP045970.1\|WP_003721302.1\|599311_600742_-\|CapA-family-protein	unknown	unknown	gnl\|CDD\|225399
NZ_CP045970.1\|WP_003721316.1\|615700_616453_+\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
NZ_CP045970.1\|WP_003721304.1\|602029_602752_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam01881_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
NZ_CP045970.1\|WP_057171662.1\|611599_613015_+\|multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP045970.1\|WP_061112175.1\|621312_622788_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045970.1\|WP_003721303.1\|600862_601678_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NZ_CP045970.1\|WP_031668875.1\|606142_608326_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP045970.1\|WP_003721306.1\|604445_605315_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|274215
NZ_CP045970.1\|WP_003721310.1\|608628_608907_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP045970.1\|WP_003721307.1\|605292_606075_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|273860
NZ_CP045970.1\|WP_061112174.1\|618964_620296_+\|DUF1254-domain-containing-protein	unknown	unknown	gnl\|CDD\|227659
NZ_CP045970.1\|WP_003721311.1\|611084_611453_-\|DUF1304-domain-containing-protein	unknown	unknown	gnl\|CDD\|226282
NZ_CP045970.1\|WP_003721301.1\|598833_599265_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP045970.1\|WP_003721320.1\|620342_621083_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133381
NZ_CP045970.1\|WP_003721315.1\|614182_615499_-\|6-phospho-beta-glucosidase	unknown	unknown	gnl\|CDD\|133432
NZ_CP045970.1\|WP_003721314.1\|613146_614151_+\|ROK-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224851
NZ_CP045970.1\|WP_003721300.1\|596897_598733_+\|lmo0514-family-class-1-internalin	unknown	unknown	gnl\|CDD\|380190
NZ_CP045970.1\|WP_031671650.1\|617047_618709_-\|SulP-family-inorganic-anion-transporter	unknown	unknown	gnl\|CDD\|223732
NZ_CP045970.1\|WP_003721317.1\|616558_617002_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP045970.1\|WP_003721305.1\|602767_604456_+\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	gnl\|CDD\|187884	cd09754, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as CXXC_CXXC family.	5.75294e-26
NZ_CP045970.1\|WP_003721302.1\|599311_600742_-\|CapA-family-protein	gnl\|CDD\|225399	COG2843, PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) [Cell envelope biogenesis, outer membrane].	1.43469e-99
NZ_CP045970.1\|WP_003721316.1\|615700_616453_+\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	5.24308e-64
NZ_CP045970.1\|WP_003721304.1\|602029_602752_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	2.75155e-33
NZ_CP045970.1\|WP_057171662.1\|611599_613015_+\|multidrug-efflux-MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.87135e-79
NZ_CP045970.1\|WP_003721303.1\|600862_601678_-\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	5.01016e-50
NZ_CP045970.1\|WP_031668875.1\|606142_608326_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	5.29289e-60
NZ_CP045970.1\|WP_003721306.1\|604445_605315_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|274215	TIGR02585, conserved_protein, CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This clade is a member of the DevR family (TIGR01875) and includes the DevR protein of Myxococcus xanthus, a protein whose expression appears to be regulated through a number of means, including both location and autorepression; DevR mutants are incapable of fruiting body development.	1.33672e-55
NZ_CP045970.1\|WP_003721310.1\|608628_608907_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	5.1393e-30
NZ_CP045970.1\|WP_003721307.1\|605292_606075_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|273860	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family is represented by TM1800 from Thermotoga maritima. It is related to TIGR01868 (CRISPR-associated protein, CT1976 family).	1.37797e-23
NZ_CP045970.1\|WP_061112174.1\|618964_620296_+\|DUF1254-domain-containing-protein	gnl\|CDD\|227659	COG5361, COG5361, Uncharacterized conserved protein [Function unknown].	8.07616e-73
NZ_CP045970.1\|WP_003721311.1\|611084_611453_-\|DUF1304-domain-containing-protein	gnl\|CDD\|226282	COG3759, COG3759, Predicted membrane protein [Function unknown].	1.10012e-41
NZ_CP045970.1\|WP_003721301.1\|598833_599265_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	4.03126e-27
NZ_CP045970.1\|WP_003721320.1\|620342_621083_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133381	cd01106, HTH_TipAL-Mta, Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA. Helix-turn-helix (HTH) TipAL, Mta, and SkgA transcription regulators, and related proteins, N-terminal domain. TipAL regulates resistance to and activation by numerous cyclic thiopeptide antibiotics, such as thiostrepton. Mta is a global transcriptional regulator; the N-terminal DNA-binding domain of Mta interacts directly with the promoters of mta, bmr, blt, and ydfK, and induces transcription of these multidrug-efflux transport genes. SkgA has been shown to control stationary-phase expression of catalase-peroxidase in Caulobacter crescentus. These proteins are comprised of distinct domains that harbor an N-terminal active (DNA-binding) site and a regulatory (effector-binding) site. The conserved N-terminal domain of these transcription regulators contains winged HTH motifs that mediate DNA binding. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Unique to this family, is a TipAL-like, lineage specific Bacilli subgroup, which has five conserved cysteines in the C-terminus of the protein.	2.56491e-51
NZ_CP045970.1\|WP_003721315.1\|614182_615499_-\|6-phospho-beta-glucosidase	gnl\|CDD\|133432	cd05296, GH4_P_beta_glucosidase, Glycoside Hydrolases Family 4; Phospho-beta-glucosidase. Some bacteria simultaneously translocate and phosphorylate disaccharides via the phosphoenolpyruvate-dependent phosphotransferase system (PEP-PTS). After translocation, these phospho-disaccharides may be hydrolyzed by the GH4 glycoside hydrolases such as the phospho-beta-glucosidases. Other organisms (such as archaea and Thermotoga maritima ) lack the PEP-PTS system, but have several enzymes normally associated with the PEP-PTS operon. The 6-phospho-beta-glucosidase from Thermotoga maritima hydrolylzes cellobiose 6-phosphate (6P) into glucose-6P and glucose, in an NAD+ and Mn2+ dependent fashion. The Escherichia coli 6-phospho-beta-glucosidase (also called celF) hydrolyzes a variety of phospho-beta-glucosides including cellobiose-6P, salicin-6P, arbutin-6P, and gentobiose-6P. Phospho-beta-glucosidases are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0
NZ_CP045970.1\|WP_003721314.1\|613146_614151_+\|ROK-family-transcriptional-regulator	gnl\|CDD\|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	1.07552e-20
NZ_CP045970.1\|WP_003721300.1\|596897_598733_+\|lmo0514-family-class-1-internalin	gnl\|CDD\|380190	NF033186, internalin_K, class 1 internalin InlK. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface-anchored proteins with an N-terminal signal peptide, leucine-rich repeats, and a C-terminal LPXTG processing and cell surface anchoring site. Members of this family are internalin K (InlK), a virulence factor. See articles PMID:17764999. for a general discussion of internalins, and PMID:21829365, PMID:22082958, and PMID:23958637 for more information about internalin K.	1.95498e-119
NZ_CP045970.1\|WP_031671650.1\|617047_618709_-\|SulP-family-inorganic-anion-transporter	gnl\|CDD\|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	1.06019e-147

>NZ_CP045970.1|WP_003721310.1|608628_608907_+|CRISPR-associated-endonuclease-Cas2
MYVILIYDISIENGGAKVWRNVFKICKKYLTHVQKSVFEGEITPALLVKLRMELDKYIRDDQDSVIVFSSRQQRWLEKEFWGLTDEKTSNFF
>NZ_CP045970.1|WP_031668875.1|606142_608326_+|CRISPR-associated-helicase/endonuclease-Cas3
MHKYLAKSNPEETIQEHTDNLLKNYQRLKKLYPAVEIDWYLLELVCLLHDLGKMNLLFQTKLGNASGKGKEIPHGYLSVAFVPDSKLEEMGYSEDEIKVVYQAIARHHERKYDFSDSEWKKEIIKLEEQWAGFIYSQLGGNAEYSSEVEMLYFYPGSRIFEGNSAADAETFKKYVLLKGLLNRIDFAASGGIDVELENDFLMDSMEVQLAHFKAENPEADWNALQKYMMQHQNENIVVIAETGMGKTEAGLLWLGNNKGFFTLPLRAAINAIYERITKNIVTTNQAERVGLLHSETYSQYLLHEGNAEMDIDEYYTRTRQMSLPITICTLDQLFDFVFRYAGFEHKLATLSYSKVIIDEIQMYSPDLLAYLILGLSYIDKFGGKFCIMTATLPGIVTDLLLENGVDFVQPEEKFVSSRIRHSMEMVHTEIESEFIKPFFNNNRILVICNTISKAKKIYSELKEHFQGEEIHLIHSQFIKRDRSAKEKAIFKDGQKDSTKKCIWVATQVVEASLDIDFDLLFTELSDVNGLFQRMGRCYRNRALDVDTNVYVFDGGAKVCSGIGTFIDKLIFVNSKTILNEHAGVLTEEKKMELVEQVYSTEALSGSEFYNDLIDKLNYVKAFESYLMNKADVRMRFRNINSVSVIPEEVWQDNAEEINSYFVTLRKTSKEISTKEKIIARTNLAEFMVSIPDYLYKKGESVVREINRYESVIEFKCGYSSDVGVFMR
>NZ_CP045970.1|WP_003721307.1|605292_606075_+|type-I-B-CRISPR-associated-protein-Cas5
MLIMKAIRVRLWQDLVNFKKPTSFQLKETYPLPPYSTVIGMVHTLCGFTSYHEMKISIQGKYFSKVNDLATRYEFKNGMTYDASRHQIKVDKYGVSRGVSTVELLVDLELLLHIIPEDPSLVPIIEKAFREPIEFPSLGRREDIATIQKVEVVDVEKRQPKKSTEISDGYNAYVPISLTENNSVHFKSHESSVGRDKLLGTRYLLTEKYERVNHGTEKAPKFFRKWRKKDVIYSSRIFVSKKDVFFFDEDDYLVFIEEEE
>NZ_CP045970.1|WP_003721306.1|604445_605315_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MKNKGLAMTIIFQAESANYGESLGNISSLKKISRNNGDQYTYISRQAIRYNLMDQIGEKEAPVKAEGGGDKKVIQFLSEATITDFPELDFFGYLKTEKGSGGQKRSAKVRLSNAISLETFKGDLDFLTNKGQADKLNENMNIAQAEIHKSYYRYTITIDLDQIGIDGEIALDNKEKARRVKKLMDTVAFLYRDIRGRREDLKPLFVIGGVYDVKNPVFQNIVDVADNNIVIKNIKDLLTYEDIKENTRVGIIDGQFANSDEVKVELKAESVPAFFNDIKGKIDAYYESN
>NZ_CP045970.1|WP_003721305.1|602767_604456_+|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1
MRTEIEVRANDWLINAGLTGFLNIVGKENVRIDGQAIYFTADLLEDFETKYFNFFIQEYKETLSWYKIVSYKETMEQFRIDEFASFDEVALGNLNKYMKDVVKFYLKKANYIKVFPLIDPSANVTKWLEKLNTINLTKKQKWDEVKADIIEEVKQTYTQLDLIIDFCASEKGLQYLGAKNLIYSVINKGWSGVSFLLKQTKFIDPYLDYKTSFLDPVIDYLDTDLSKAKYNCFNCNQPIKNLKLDLSFMNDVGFDTARKTAHVWDFNNDVATCPICRLIYSCVPAGFTYVYGEGMFVNDSYGVEELHRVNERMRNSILRFNKDGINSTNTYRALVESITMEHENNRRYELADIQLVRYENEHYRFNLLSKKMLHIVNDSKGILKSLIRCGYKEGNLNVNLYKEVIQHLMNNENLFTLIHKLIYYKQTSVNGLYYNMGHVSGILDINTKFLKEMEVMTNISQNQLWFVQNCGKEFKEGYVKKKSENKISGITYKLLNSLKVNDKDGFMDTLLNSYSYLSMPIPDVFIKMFSNNEAFKSVGYAFMLGVGGEKTKKEDGGNTDEK
>NZ_CP045970.1|WP_003721304.1|602029_602752_+|CRISPR-associated-endoribonuclease-Cas6
MRLKINCDFDSKIISKDFQSKVVSLFKAGIMKSSPERYENLFGGNKHKQYTFSVYLPKPQNKGAEIQLNEANCIINFSTGDAETGIIFYNALMSLRGSKVLFGAGNHITVKNIQIVPEKKIIGKRTILRTLSPVVSRDHNRETFKNWFYSFEDEEFEPTLKRNMLPYLMDAFGEQARYDLEKLKITPISMKKVVVYCHEIHIESSVGIFELEAEAYLQKYLVENGIGTMTGSGFGMIEQF
>NZ_CP045970.1|WP_003721303.1|600862_601678_-|histidine-phosphatase-family-protein
MKKNIFKLLMALCAVLLIAGCGNSTSADKKETKETKEDGTVTFYVVRHGKTMLNTTDRVQGWSDAVLTPAGEEVVKSAGKGLKDVDFSAAYSSDSGRAIQTANLILKESDKSADKEVQTDPRFREFNFGSYEGDLNENMWTDIAKSQGKTLEEWQKAGLSPKDFANSVAALDKTRVKEGENWPAEDYATIQARLKEGLTDVAKKESKNGDSNVLLVSHGLSIGALLDTIEPGYKLPAEGIKNASVTKITYKDGKFTIGDVNDLSYVEKGSK
>NZ_CP045970.1|WP_003721302.1|599311_600742_-|CapA-family-protein
MKRRTYVIITGLVLIFIAGAFWITNSTNQSDQKATQTEPLKKTSPANVKTISSEAKKTLNSLASSGADKASISDLNQLIKELKSYPVEKNDSGAYLQNLTACLEAVKSYTTGKADEKTLGKVYPAFLASEQKLSAIEKTNQYDWFYAAAATNQQGLKEKGVVTLTMVGDNSFGTYPETPEHLKFDNVFQKNNGNNTYVYKNCLPWFKSDDYTIINAESAFTNATKAENKKWRIKSDPAHVAFLPASGVEAANLANNHTMDYFQVGYDDTLKAFKENNIPVFNTDAPLETTIKGMKTVLLGYDCRMSQQSPAYLERIVKDVKKYKKEDTLVIVNMHWGVEYRETPTDYQTQFGHAILDAGADIIMGSHPHRLESVEKYKDKYIVYSMGDFAFGADPTLLSRMTSMFQLRFTKEDNKIVLKDISIVPTYENSDGSTTENNYQPLPVFGDDAKKIVDELNRISKPIKGGVTEYTYFDPF
>NZ_CP045970.1|WP_003721301.1|598833_599265_+|universal-stress-protein
MEKYHRILVAVDGSEPAKLAFEKGLELALKLDGVLGIASIVDLRAFSPNVSYDGSLEEKAELELKTSVNEYAEKARTAGVKQVETFVAKGNPKILLSTDIPAEFQADLIICGATGMNRVEKLVLGSVSSYIMAHAICDTLIAR
>NZ_CP045970.1|WP_003721300.1|596897_598733_+|lmo0514-family-class-1-internalin
MKKALKLFLAMICMFIMIYPSTAAHAEETNIVNIPDANLKTYLNGLLKQASDAPITKTQMNTIQTVTLSGSTYTDLTGLEEAGNLVTLSLNNTNIQTLEPIKNQTSLTYLTVGGDNVKDSLFVDLNGLVNLQSLSINGSEVTHNVFKTFNKLPKLTYLYAQNSMKITDISALASLPALTTLFLQFDGIDDFRPLNDFESFKNGNLKALAAFGQNTGRTNPRITLKSGKLDYNETNQTLYLPFSMMPKPLTSFDGTVAPFSKSTSASNTYLGFNDVALPSARLSITEDGITVSGVTKEEFDNLDEIEYNARYDFPTGSYPTPPSMTSYTISSGTYDQYFDISHTLDLTADESFDYNQYDTTSEEQFLKDVHAETDDGTAVKSDFDQVVKLDVPGEYTVTLNAENAAGLKATPVTVKVTVHEKPVITSDSQISYKKETTKSVDEFLKEIHGSVTGNAVLTSDFDKVVDLNTPGEYTVTLNAINDRGQKADPVTVVVTVTTSDSGHVNPVPPTPEVKPTPQEETDQTIIPEPQSETTEDSVKEDQAKDGQAKSEEKADKTSLTTKENKVEKSEKTNQPKTKALPQTGDTNKTALPIAGVMLSLAALLIFRKSKS
>NZ_CP045970.1|WP_003721311.1|611084_611453_-|DUF1304-domain-containing-protein
MAILAFILTFIVMIEHIYIMILEMFFANTKLAAKTFGVEKELLANKKVQTLFANQGLYNGFLAAGLVWGLFFAGAGMAETVQIFFLSCVVVAALFGGATSSKGILVKQGLPAVLALVVVLLV
>NZ_CP045970.1|WP_057171662.1|611599_613015_+|multidrug-efflux-MFS-transporter
MQQEATGGQKIRPIPIIASFLMAGFIGLFSETALNMALSDLIQVFDISSATVQWLTTGYLLTLGILVPISGLLLQWFTTRGLFFTAVSFSIAGTLIAALSPTFAMLMIGRVVQAVGTALLLPLMFNTILLIFPEHKRGSAMGMIGLVIMFAPAVGPTISGLILENLTWNWIFWISLPFLIIALLFGMKFMQNVSVVTKPKIDILSIILSTLGFGGVVFAFSSAGENGWGSATVLVSIIVGGLALGLFVWRQLTMEKPLMDLKVFKYPMFTLGLILVFISFMMILSTMILLPLYLQNSLALAAFSAGLVLLPGGVLNGLMSPFTGRLFDAYGPRALVIPGFIVAVVALFFLTRIEVGTSALTIIVLHSVLMIGIPMVMMPAQTNGLNQLPRKLYPDGTAIMNTLQQVSGAIGTAVAITIMSAGQKAYMETAQGVGPEQMVASLTAGIQNAFVFGLIMACIGLLCSLFIRKAK
>NZ_CP045970.1|WP_003721314.1|613146_614151_+|ROK-family-transcriptional-regulator
MAIPRDLKELNKKNIKSILRQQGAMTKAEIAEVTGLSVVTVNKLIRDLVENEEILEQDNSVATGGRRAVSYEINPNFQQVLVISLQEKWKKITYSFSVYNLLGEPEFVEDMSGEDLDITALKRNTKDIICAFPKISCVVIGVPGIEIGGKLRAMDFPLLLNVQLRETLEAEVNLPVLVETDTNAAILGYKNRPVKEENIVGLYYPERFPPGAGLLMNGEILKGQNGLAGEIKHMPLQVDWDNFDFSVDEIKAHIRKMVLLTMSFYDPETIVLYTNFYFGQKDFMEELKEELKQVYPYAVLPEIVLSRKFTTDYRIGLLAFGIDYLENNMTDWRI
>NZ_CP045970.1|WP_003721315.1|614182_615499_-|6-phospho-beta-glucosidase
MTKGIKIATIGGGSSYTPELIEGFIKRQDELPVRELWLVDVEAGREKLEIVGNLAKRMVKKAGVNMEIHLTLDREEALKDADFVTTQLRVGLLDARVKDERIPNSYGVVGQETNGPGGMFKGLRTIPVILDICKDMERLCPDAWLINFANPAGMVTEAVLRYSNQKKVVGLCNGPIGIERNIAETLGVDVSEIYVEFVGLNHMVFAKTVYHNGKDVTKDVVFKMTEDEAGSSLKNINATGWDKTFLRTLNMIPIDYLRYYWQTKQQLEDQARAYAEHGTRAEVVKKVEAELFELYKQEELAEKPKQLEQRGGAYYSEAACNLINSIYNDKRDIQIVNTRNNGAILDIDPDSAVETNCVITRQGPIPLASGRLPIAINGIIQEIKTFERLTAEAAVTGDYDKALLAMTINPLTPSESVAREMLDELLEAHKEYLPNFFK
>NZ_CP045970.1|WP_003721316.1|615700_616453_+|MurR/RpiR-family-transcriptional-regulator
MLFLDKNLELNDTELDIYNYIVANLDKVVYMRIRDLATEAHVSTTTILRFCRKFGCNGFSEFRVKLQLYLEEQKLAQIDMADETTYIDFLKRTAQPEFKAQIQNAVEILRDRELVLFAGVGSSGVIAEYGAIYFSSLFTLALHIEDPLNHPFYHLSSKLSDKICMIAISVEGENEDIIRYIHQLKAQNCKVISITNSAKSTIARLSDANIAYYINKEMYQEANITSQLPALYTIENIAREIRTQLDKEKM
>NZ_CP045970.1|WP_003721317.1|616558_617002_+|hypothetical-protein
MYSNMKEKVVFTLIMCSLMILCMSSYNIFLENGIGTDSLLIVLKAFVPFLFIGFLLDFFVVGKIVYRLHALLVSEDASKFKKIIMMQLLMVTFMCVLMSTLSLIVNQGEWSHLGILILRNYFVALFLQIFIVSPFVRLISPRIFALL
>NZ_CP045970.1|WP_031671650.1|617047_618709_-|SulP-family-inorganic-anion-transporter
MFKHILLSLNGYKISYLRNDVISGVGVAALTIPVAMGYAQVAGLPPIYGLYASFLPVIAYVIFASSPQLIFGIDATASAITGSIILGTAGLAAGSKEAIALAPILAFFCAIFLVLFSVLKLGRFAKYISAPVLSGFISGLSVSIIMGQIPKIMGLKESGDSFFSSLGIIFGQFFQSNWISFAMGVVTVIIVITCKKVIPKIPMSLVVLVLGTMAAYFFKLDQYNVDIVGKIPVGFPSLALPDFGASSWALAIGGGLVCAIATFAGSLLPSESFAMRNKYTIDDNRELFAYGVSNFVAAFSGCSPASASVSRTAANEQFRGKTQMVSIVAATIIALIVAFLSGLLYYMPQPVLSGIVFAALVGIIDVDVLKGLFKVSRREATVWIVAALGTLLVGVIFGVLLGIFLSFINVVSRSMKTPIAILGVIEGRHGYFDLKRKPEAKPIPNVVIYRYSASLFFGNFNKFADGLKEAVQDDTKLVIFEASAIINIDTTATESMKDLLKWLDDKGIEYYFADLIDHLKTSFRKHDLGYLIDNGYTKKTVEDALDAYYAEHK
>NZ_CP045970.1|WP_061112174.1|618964_620296_+|DUF1254-domain-containing-protein
MATQKNLVDLATKAYIYGFPFIFNTQQIERYVTVGIGGTKQVPFNNFTHASRLAEPSDKFVSVNNDTIYSNAPIDVSAGPVVLSVPDTSGRYYVLQFVDAWSNNFAYVGKRATGTSAGKFLLTPPNWNGDVPADMIEIKFPTNIGIIIGRLACDGEADLPTVRELQEQLKITPLNEGKEVDGFPEYDRSLGKELAFFEQLRVYMAQFPPAERDLVKQESFAPIGLMEKGVSPYSNPSEELKNALIEGAKAGLANIKKATTNFKSENGWGLTQHLFDYNADFFEIGTKKSLDWVIEDREEAYIIRAVSAITALWGNHGYEAVYLMTWTDTDGKALNGKNKYTLELNPIPPVDSFWSITMYDLPEYFLCENPINRYSIGDRTPGIQYNDDGGITIVVSKDEPTDPKERANWLPAPDAEFRPMFRLYNPQQPLVDGSYHFSGFEKK
>NZ_CP045970.1|WP_003721320.1|620342_621083_-|MerR-family-transcriptional-regulator
MQIKELAELTGVSVRTLHHYDKIGLLVPQKDDWNGYRIYSEKDVDKLQQILFFKELDFPLKKIQQILDDPLFDKNVALDMQRHLLIEKKQRIETMLATLDLTIKNEKGEITMTNKEKFTGFDFSSNPYEEEARKLWGDKVVEKANEKVNNMSEKEQLTLKESFDAEFRHLASVRKLTPESEEAQLEIDHFFHYLNDTHGNIYSLEAFASLGEMYVNDERFTKNIDQFGDGLSQFLQEAMTIYAKNK
>NZ_CP045970.1|WP_061112175.1|621312_622788_+|hypothetical-protein
MIRKVKSISMWLWHHVTPQIFAVICVFIITIIALFMPPYIGMADNGDFFRIFSSNGLFVNNTNYDALQFGHFVKEFGIYQYFNENQVAIYSSQSIFIQMALLLNKLFWSTTVFDVRFLGGLQLALLLPAIYLLVAGLTAKMKGWPGYVVAALTVFIFADTAYTAYFNSFFSEGLILIMMLYISAGFLLLYQHKYNDYAMLGLIFVASLILITAKQQNAPIAVVIAVCGILVFFIRKNRAFRISAAATFLVIFLSGVVMYAFIPGEFVTINQYQTMTRGVLLDSENPEKSLEEMGMNSEFALLKGTNFYQKYKMIDLDSKLMEKEFYSNYNFVTVLSYYLENPKQFGKMLDLSAQNSFSIRPFEMGNFEKATGYKFKEKTHFFSAYSDVKEKFAPAKFTFLILWALVFLICYGVSAFKHFREKNIRGTLLFDLIVLLIGSGFAVILVTIVGDGEADLTKHNFLFNVCFDLTMLIGAASLLEVYLKKRGERNA

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Crispr_ID: NZ_CP045970_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045970_4

2569152-2569313

Orphan

Consensus_repeat	Method
TTTTTTTATGGAAACAACGCTCCACTTCGTTACGCCTTGTATTGGAGTTCTAGGG	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of NZ_CP045970_4

>merge|NZ_CP045970|4|2569152-2569313|CRISPRCasFinder
TTTTTTTATGGAAACAACGCTCCACTTCGTTACGCCTTGTATTGGAGTTCTAGGGGATTGGTTGAATTTAATAATTTGTGCTTCCTTTTTCGGGTTGTTCGTCCACTTTTTTTAATGGAAACAACGCTCCACTTCGTTACGCCTTGTATTGGAGTTCTAGGG

>NZ_CP045970|4|3|2569152-2569313|CRISPRCasFinder
TTTTTTTATGGAAACAACGCTCCACTTCGTTACGCCTTGTATTGGAGTTCTAGGG	GATTGGTTGAATTTAATAATTTGTGCTTCCTTTTTCGGGTTGTTCGTCCACT
TTTTTTAATGGAAACAACGCTCCACTTCGTTACGCCTTGTATTGGAGTTCTAGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045970.1\|WP_010989997.1\|2575537_2576728_-\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
NZ_CP045970.1\|WP_057171509.1\|2577904_2578951_-\|sugar-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225263
NZ_CP045970.1\|WP_003727923.1\|2571774_2573067_-\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP045970.1\|WP_003772391.1\|2571498_2571672_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045970.1\|WP_003723342.1\|2552312_2552696_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226231
NZ_CP045970.1\|WP_003723344.1\|2553691_2554261_-\|YdcF-family-protein	unknown	unknown	gnl\|CDD\|99750
NZ_CP045970.1\|WP_033918293.1\|2565862_2568244_-\|ribonuclease-R	unknown	unknown	gnl\|CDD\|273947
NZ_CP045970.1\|WP_003723349.1\|2564414_2565323_+\|Rgg/GadR/MutR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP045970.1\|WP_003723348.1\|2560756_2564032_-\|carbohydrate-binding-protein	unknown	unknown	gnl\|CDD\|224418
NZ_CP045970.1\|WP_003723346.1\|2559751_2560696_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275380
NZ_CP045970.1\|WP_003723352.1\|2568277_2569024_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|224561
NZ_CP045970.1\|WP_003732482.1\|2569720_2570464_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|224561
NZ_CP045970.1\|WP_003733912.1\|2554436_2554856_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP045970.1\|WP_003732485.1\|2576862_2577873_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|273675
NZ_CP045970.1\|WP_003723925.1\|2574736_2575492_-\|triose-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
NZ_CP045970.1\|WP_003723343.1\|2552750_2553647_-\|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NZ_CP045970.1\|WP_003727926.1\|2569387_2569621_-\|preprotein-translocase-subunit-SecG	unknown	unknown	gnl\|CDD\|224233
NZ_CP045970.1\|WP_003723350.1\|2565382_2565847_-\|SsrA-binding-protein-SmpB	unknown	unknown	gnl\|CDD\|376590
NZ_CP045970.1\|WP_009925021.1\|2570646_2571366_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP045970.1\|WP_003732483.1\|2573202_2574735_-\|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|235463

Protein	Function_ID	Function_description	E-value
NZ_CP045970.1\|WP_010989997.1\|2575537_2576728_-\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NZ_CP045970.1\|WP_003727923.1\|2571774_2573067_-\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP045970.1\|WP_003723342.1\|2552312_2552696_-\|hypothetical-protein	gnl\|CDD\|226231	COG3708, COG3708, Uncharacterized protein conserved in bacteria [Function unknown].	8.8134e-16
NZ_CP045970.1\|WP_003723344.1\|2553691_2554261_-\|YdcF-family-protein	gnl\|CDD\|99750	cd06259, YdcF-like, YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been idenitified. The family also includes Escherichia coli sanA and Salmonella typhimurium sfiX, which are involved in vancomycin resistance; sfiX may also be involved in murein synthesis.	2.8348e-39
NZ_CP045970.1\|WP_033918293.1\|2565862_2568244_-\|ribonuclease-R	gnl\|CDD\|273947	TIGR02063, Ribonuclease_R, ribonuclease R. This family consists of an exoribonuclease, ribonuclease R, also called VacB. It is one of the eight exoribonucleases reported in E. coli and is broadly distributed throughout the bacteria. In E. coli, double mutants of this protein and polynucleotide phosphorylase are not viable. Scoring between trusted and noise cutoffs to the model are shorter, divergent forms from the Chlamydiae, and divergent forms from the Campylobacterales (including Helicobacter pylori) and Leptospira interrogans. [Transcription, Degradation of RNA].	0
NZ_CP045970.1\|WP_003723349.1\|2564414_2565323_+\|Rgg/GadR/MutR-family-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.22542e-08
NZ_CP045970.1\|WP_003723348.1\|2560756_2564032_-\|carbohydrate-binding-protein	gnl\|CDD\|224418	COG1501, COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism].	0
NZ_CP045970.1\|WP_003723346.1\|2559751_2560696_-\|hypothetical-protein	gnl\|CDD\|275380	sd00033, LRR_RI, leucine-rich repeats, ribonuclease inhibitor (RI)-like subfamily. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.	4.02295e-06
NZ_CP045970.1\|WP_003723352.1\|2568277_2569024_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|224561	COG1647, COG1647, Esterase/lipase [General function prediction only].	3.8639e-136
NZ_CP045970.1\|WP_003732482.1\|2569720_2570464_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|224561	COG1647, COG1647, Esterase/lipase [General function prediction only].	1.94931e-122
NZ_CP045970.1\|WP_003723925.1\|2574736_2575492_-\|triose-phosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	7.345e-145
NZ_CP045970.1\|WP_003732485.1\|2576862_2577873_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	0
NZ_CP045970.1\|WP_057171509.1\|2577904_2578951_-\|sugar-binding-transcriptional-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	6.12803e-90
NZ_CP045970.1\|WP_003723343.1\|2552750_2553647_-\|YafY-family-transcriptional-regulator	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	1.6084e-71
NZ_CP045970.1\|WP_003727926.1\|2569387_2569621_-\|preprotein-translocase-subunit-SecG	gnl\|CDD\|224233	COG1314, SecG, Preprotein translocase subunit SecG [Intracellular trafficking and secretion].	6.04836e-13
NZ_CP045970.1\|WP_003723350.1\|2565382_2565847_-\|SsrA-binding-protein-SmpB	gnl\|CDD\|376590	pfam01668, SmpB, SmpB protein.	2.29197e-92
NZ_CP045970.1\|WP_009925021.1\|2570646_2571366_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	4.31126e-18
NZ_CP045970.1\|WP_003732483.1\|2573202_2574735_-\|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	gnl\|CDD\|235463	PRK05434, PRK05434, 2,3-bisphosphoglycerate-independent phosphoglycerate mutase.	0

>NZ_CP045970.1|WP_003723352.1|2568277_2569024_-|alpha/beta-fold-hydrolase
MKITPPQPFLFEKGKRAVLLLHGFTGSSADVRILGRFLQENNYTCYAPQYRGHGVSPDLLLKTGPNDWWEDVLEAYDHLKSLGYTEIAVAGLSLGGLFSLKLGFSRPLKGIIAMSTPTRMDSSSPIIQGFLDYVRNYKKLEGKTTEQIDAEMVAYKDAPMNTIAKLKDEISGVVAEIDMIYAPIMVVQGEKDDMVDVSGAQLIYDTVESTKKELHWFKESGHVITLDKERKEVNQAILTFLDSLDWQE
>NZ_CP045970.1|WP_033918293.1|2565862_2568244_-|ribonuclease-R
MEQKQMEEKIMNLLTSAPDKTFALEDLEIEIALNNADDFKLMVKALVKLEDSGTIVRSRKNRYALPEKMDLVKGTFRAHERGFGFVLPEEKEMDDIFIPPNEVKDAMNGDLVFATITKRKGDNLAEGTIKKIVERKTTQIVGTYMEDLAGIPIVMPDDKRLFGEVEIDLEDGLKPVDGHKVIVELTEYATGHARARGVVKSIIGHRNDPGVDILSIIHKHGISIGFPEEVMEQVSKAPDVVDDSDIGNRRDLRDQMIITIDGADAKDLDDAVTVKQLPNGNWKLGVHIADVTHYVTEGSPLDIEAQERGTSVYLVDRVIPMLPHKLSNGICSLNPQVDRFTMSCEMEIDQEGHVVNHEIFESIIKTTERMTYTDVNDILVEKDEALREKYAPIVPMLEAMQNLAEILRRKREKRGAIDFDFKEARVVVDEEGHPEAVVMRERSAGEHLIEEFMLAANETVAEHFHWMDVPFIYRIHEDPKEDKLARFFEFITNFGLIVKGTANDIHPAALQQVLEEVKGKPEEMVVSTVMLRSMQQAKYDTVSAGHFGLSTDFYTHFTSPIRRYPDLIVHRLIREYLINGDVRPETLEKRAEELPEIAEHSSKMERRAVEAERETDELKKTEFMVDKVGERFIGIISSVTNFGLFIELPTTIEGLVHVSAMKGDYFKFHQNQLAMIGERTGQIYRIGDEVEVEVTKVDVDAREIDFALRSEGKPGPVSDKQKRQREKPIDKTRNFKSSSKNNRNKRRTGKSEDVKPKTERKDDEWYTKPKKKKKKKPFYQGVAKESPKKKKRR
>NZ_CP045970.1|WP_003723350.1|2565382_2565847_-|SsrA-binding-protein-SmpB
MPKGDGKLVAQNKKARHDYAIEETFEAGIVLQGTEIKSVRNARVNLKDSYARIDKGEIFLHNMHISPYEQGNRYNHDPLRTRKLLLHKKQISRLIGETKESGYSIVPLKMYIKDGYAKVLIGVARGKKKYDKRQDLKQKEAKRDIERAFKERQQ
>NZ_CP045970.1|WP_003723349.1|2564414_2565323_+|Rgg/GadR/MutR-family-transcriptional-regulator
MQNVGDTLKFIRKSKNLTQQEACTGALSRSNYQKIENNKIMPSMDRFIQLLLNFNMTLEEFEFVKRDFTPSPKENILYLYSKIITSSETDILLDVISKCDEYLATQNDYFISDIKASLEGILLVEKEHDFELARQKVTYIWDRLSEADELFWNDILILRNIFFIFENETAQHIVNRLIKQLKKYRYLHPTLPIEISLHVNRATYLILDEKYELALHYIEQSIKIAKQNHYYLQFCMAIAKKGIVLYKLGQKQDGKRFMQRALRVAKFLEEERILNGIKNEIDYFLHDELPVLSLNEFTKIDI
>NZ_CP045970.1|WP_003723348.1|2560756_2564032_-|carbohydrate-binding-protein
MKRRTRKCSLVFILGILIFSCLSGFGTNVFAMDGEYHSPYGDDDLYSVQPTERSPRDPKAGEDVILNITTWPIEDGQNVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQKERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEAYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDINARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDLWNGGIHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLGAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFAHLTNVSTASDHAGYTGTGFVAGFDAEKEAVEFDVDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTADWDTWSTIEVPVTLQAGNNQVVFDFEADDTAGINFDHVVFKK
>NZ_CP045970.1|WP_003723346.1|2559751_2560696_-|hypothetical-protein
MKKIIGLAFIAFCCILFAPTIKAQADTVPLPAPIIEAFPVEAIAEAIAGELDKDSVNDTITQADLDTMTFIPLPSLGLTGEDLSVLNNEVFTNAIELAIWSNNIGELPDLSDALPALENIEANGANITLFPDANYPNLTNADLSQNNFGFNIPKFVGMEALESINISDAGLSGYVAEDIWMNMPNLDSLLLNENHLISIPEDIFLSEQLSTHSFANQTATYPHTTIKQGENLEVFVPFIYQALDFIAPSKHDLIIIKDNGRTLYEPPYPTYDGSYMYKIETAGLQPGEHLLEISLGYNSGEYTGWYDFPVTITE
>NZ_CP045970.1|WP_003733912.1|2554436_2554856_-|hypothetical-protein
MYRLLSIAFFGIAVICLLFPWMSSGIDAATFELVYEPAYKLIWMQPIIIVGYLGFLCTIFIPKFQRGKNRIVPFIGILILVLGLLNLAVRPLFGFDSFNFSIIDAYVSELVEPAFLIAVSASILSLIMYAIYLKKLENL
>NZ_CP045970.1|WP_003723344.1|2553691_2554261_-|YdcF-family-protein
MRSLRKIVIILIIIGFMYLLIVAAFMFSGSRTKPSENADTVLILGAKVKGNPAVPSLVLQERLDAAVAYLNEYPKAKVIVSGGQGADESATEASVMEEYLVNEGIARKRIETETKSKRTEENIKYSNAKFNLGKTVIVTSDYHMYRALMLAKRQGIDASGLPATSQTFAKYKGMMREVLSITYAWVFDH
>NZ_CP045970.1|WP_003723343.1|2552750_2553647_-|YafY-family-transcriptional-regulator
MKLERILAILVMILERKVLASELAEKFEVSTRTIYRDMDTLLYAGFPVVALPGKNGGFTMLDTYKLATFTFSEAEKQILLEALEARSEFMLNDSQEILREKITLLQTEKPTSKHIFFDSATQHRQQIEAEVKRKIAYIQKAFTTNKQLKITYIAMSGAETTREISPQKLNLMDGSWYLEAYCHKRAAIRHFKLTRITSLKEIDKAIMEVEEKEYQPAEMKRIVLEFPKNQLGKLLDYFLQEEMETGDDYVRVSFFYDLERNIIPFLLMFGSAVKILEPASLQKDYKSEVEKLYFNLNC
>NZ_CP045970.1|WP_003723342.1|2552312_2552696_-|hypothetical-protein
MILQENIEIFGKKIRVNNDNFSPIAELWGDVMVDKPAGDIFAVYSNYASDYKGDYDLLVGTKDWDEEKSVLIEVGDYLVFSVDNASHKGVEETWQKIWARDSELKRAYKTDFEWYHTSGEIDIYISI
>NZ_CP045970.1|WP_003727926.1|2569387_2569621_-|preprotein-translocase-subunit-SecG
MSTVLTVLLIIVSVLLITVIILQPGKSAGLSGAISGGAEQLFGKQKARGLELILHRTTIVLSVVFFAILIALAYFVQ
>NZ_CP045970.1|WP_003732482.1|2569720_2570464_-|alpha/beta-fold-hydrolase
MSADRSFTLKAGNRAVLLLHGFAGTTEDVRELGEILAENGYTVHAPNFRGHGDEPAIFLKTTPEMWYEDAVAGYRQLEKDGYDEIAIVGVAMGGVFALKMAESFSPKAIVPLCANVNRKMRYIPIENYLTKQLKKQGIVEQEADQMLKNYLPEIDVMTEARATFYKNVARDIEKIHVPTMIGQGCQDEEIDADNANYIFKHIHTNDKQLCFYAGSGHDIVNDCEKDILEEDLIYFLDDLVWLEEKVV
>NZ_CP045970.1|WP_009925021.1|2570646_2571366_-|alpha/beta-hydrolase
MIAEINGINLFYQIIGKGEPILLIHGNGQNHRSLKRMIDDLSTNHQVIAVDSRAHGKSEAGNTPLDFEVMALDMLSLLDYLKIDKYKVIGYSDGGIVALVMGKMQPNRQIASVVIGTNYHVNQIRFLPDLFCRVAYGAAFLLAPFSRFFERMKRQLALTIYHPHMSEADLQKISAPLLAVVGEYDLISSKDTRKMVHSVQHGEMVIVRNGLHYLPRQKPKQLLQLIHSFFSNLSAEIHK
>NZ_CP045970.1|WP_003772391.1|2571498_2571672_-|hypothetical-protein
MLMKVKNSQASKVLETPKIKDAVVHEKSHPLAEKHSVQKKIINADMPQQQFHRRLMK
>NZ_CP045970.1|WP_003727923.1|2571774_2573067_-|phosphopyruvate-hydratase
MSIITEVYAREVLDSRGNPTVEVEVYTEAGAFGRALVPSGASTGEYEAVELRDGDKARYLGKGVLKAVENVNDIIADKIIGFDVTDQIGIDKAMIELDGTPNKGKLGANAILGVSLAAARAAADELGVHLYEYLGGVNGKVLPVPMMNILNGGEHADNNVDVQEFMVMPVGAPNFKEALRMGAEILHALKAVLKGKGLNTGVGDEGGFAPNLKSNEEALETIMQAIKDAGYKPGEEVKLAMDAASSEFYNRETGKYELKGEGVTRTSEEMVTWYEEMITKYPIISIEDGLDENDWDGFKLLTERIGDRVQLVGDDLFVTNTTKLKEGIEKGIANSILIKVNQIGTLTETLDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPTRTDRVAKYNQLLRIEDNLADLAEYHGNDTFYNLKK
>NZ_CP045970.1|WP_003732483.1|2573202_2574735_-|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase
MSKSPVAIIILDGFGKRAETVGNAVAQANKPNFDRYWANFPHGELKAAGLDVGLPEGQMGNSEVGHTNIGAGRIVYQSLTRIDKAIEEGEFQENKALNNAFTHTKENNSDLHLFGLLSDGGVHSHINHLVALLETAKDKGVKNVYIHAFLDGRDVAPQSSLEYLETLEKAISDLNYGAIATVSGRFYAMDRDKRWERVEKAYKAIVSAEGEKFEDPIELVKASYANDKNDEFVVPAIITKDGKPVATVKDNDAVIFFNFRPDRAIQLSNAFTDKEWDHFDRGADHPKNIKFVTMTLYNPSVDAEVAFEPIEMKNVIGEVLSNEGLAQLRIAETEKYPHVTFFMNGGRNEEFPGESRILINSPKVETYDLQPEMSAYEVTDALVEDIKNDKHDAIILNFANPDMVGHSGMLEPTIKAIEAVDENLGRVVDLILEKGGSAIIFADHGNSETMSTPEGKPHTAHTTVPVPVIVTKKGVTLREGGRLADVAPTMLDLLGVKKPAEMTGESLIQK
>NZ_CP045970.1|WP_003723925.1|2574736_2575492_-|triose-phosphate-isomerase
MRKPIIAGNWKMNKTAAKAGQFAEDVKNNVPSSDAVESVVAAPALFLQELVRLTEGTNLRVSAQNCYFEDEGAFTGEISPFALADLGVSYVIIGHSERREYFHETDEDINKKAHAIFKHGMTPIICCGETLDQREAGQTDTWVRGQIRAALAGLTEEQVIKSVIAYEPIWAIGTGKSSTSADANETCAVIRAEVADAVSQKAADAVRIQYGGSVKPENIADYLAESDIDGALVGGASLEPASFLALLEAVK
>NZ_CP045970.1|WP_010989997.1|2575537_2576728_-|phosphoglycerate-kinase
MAKKVVTDLDLKDKKVLVRVDFNVPMKDGKITNDNRIVAALPTIEYILEQNGKAILFSHLGKVKTEEDKEGKSLRPVAVRLSELLGKEVKFVPTTRGPELEKAIDELKDGEVLLFENTRFEDIDGKKESKNDPELGKYWASLGDVFVNDAFGTAHRAHASNVGIASNLESAAGFLMEKEIKFIGGVVDNPARPLVAILGGAKVSDKIGVIENLLTKADKVLVGGGMTFTFMAAQGQEIGKSLLEADKVELAKGLLEKAGDKLVLPVDAVVSKEFSNDAPFHTVSADSIPADEMGLDIGQATIDLFTKELQGAKTVVWNGPMGVFELSNFAKGTIGVCEAIANLTDATTIIGGGDSAAAAMDLGFADKFTHISTGGGASLEYLEGKELPGVASISDK
>NZ_CP045970.1|WP_003732485.1|2576862_2577873_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MTVKVGINGFGRIGRLAFRRIQNVEGIEVVAINDLTDAKMLAHLLKYDTTQGRFDGEVEVHDGFFKVNGKEVKVLANRNPEELPWGDLGVDIVLECTGFFTAQDKAELHIKAGAKKVVISAPATGDMKTIVYNVNHETLDGTETVISGASCTTNCLAPMAKVLEDKFGVVEGLMTTIHAYTGDQNTLDAPHPKGDFRRARAAAENIIPNTTGAAKAIGEVLPTLKGKLDGAAQRVPVPTGSLTELVTVLDKKVTVDEVNAAMEAASDPETFGYTSDQVVSSDIKGMTFGSLFDETQTKVLTVGDQQLVKTVAWYDNEMSYTAQLVRTLEYFAKIAK
>NZ_CP045970.1|WP_057171509.1|2577904_2578951_-|sugar-binding-transcriptional-regulator
MSDLINIQKKLLPDVLLIMQKRYQILRSIYFSEPVGRRTLAGMLGMSERVLRGEVEFLKAQGLVEIASSGMTVTKEGLVVFRDLENVMNQLSGLHSMEEQLAKKLQIKKCLVVQGDSDDTPWVREEMGRVAVEQLDMALTEKRNIVAVMGGSTMATVAEMMTTDFAKGRELLFVPGRGGIGEDLDNQANTICDKMATKTNTKHRVLYVPEQLGEEAYRSLLKEPAIQEGLRLVQSANAIILGIGDALAMAKRRHTGEDVLGKIIHRKAVGEAFGYYFDEQGEVVHKVPTFGLQFEDLAQIPHIIAVAGGTSKAKAIKSYMKSAPKNTILITDEGAAKSLLKGSNTLLK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP045970_1	1.6\|554982\|39\|NZ_CP045970\|CRT	554982-555020	39	NZ_CP045970.1	552777-552815	2	0.949

1. spacer 1.6|554982|39|NZ_CP045970|CRT matches to position: 552777-552815, mismatch: 2, identity: 0.949

cgtgccatgtttgctggttgtactagtcttgaagtgtta	CRISPR spacer
cgtgccatgtttgctggctgtactagtcttgaagcgtta	Protospacer
*****************.****************.****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP045970_3	3.11\|609784\|36\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	609784-609819	36	NC_003216	Listeria phage A118, complete genome	18563-18598	0	1.0
NZ_CP045970_3	3.11\|609784\|36\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	609784-609819	36	AJ242593	Bacteriophage A118 complete genome	18563-18598	0	1.0
NZ_CP045970_3	3.15\|610041\|34\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610041-610074	34	NC_003216	Listeria phage A118, complete genome	19172-19205	0	1.0
NZ_CP045970_3	3.15\|610041\|34\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610041-610074	34	AJ242593	Bacteriophage A118 complete genome	19172-19205	0	1.0
NZ_CP045970_3	3.6\|609459\|36\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	609459-609494	36	NZ_CP011399	Listeria monocytogenes strain CFSAN008100 plasmid pCFSAN008100, complete sequence	60125-60160	1	0.972
NZ_CP045970_3	3.6\|609459\|36\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	609459-609494	36	NC_009812	Listeria phage B025, complete genome	27503-27538	1	0.972
NZ_CP045970_3	3.25\|610689\|36\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610689-610724	36	NC_021539	Listeria phage LP-030-2, complete genome	14044-14079	1	0.972
NZ_CP045970_3	3.25\|610689\|36\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610689-610724	36	AJ312240	Bacteriophage PSA complete genome	14022-14057	1	0.972
NZ_CP045970_3	3.26\|610754\|37\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610754-610790	37	KY705255	Streptococcus phage P0095, complete genome	33666-33702	1	0.973
NZ_CP045970_3	3.26\|610754\|37\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610754-610790	37	KY705251	Streptococcus phage P0091, complete genome	32778-32814	1	0.973
NZ_CP045970_3	3.26\|610754\|37\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610754-610790	37	KX879643	Streptococcus phage CHPC1151, complete genome	31697-31733	1	0.973
NZ_CP045970_3	3.26\|610754\|37\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610754-610790	37	MK202161	Streptococcus phage CHPC1282, complete genome	32484-32520	1	0.973
NZ_CP045970_3	3.26\|610754\|37\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610754-610790	37	KY705252	Streptococcus phage P0092, complete genome	31845-31881	1	0.973
NZ_CP045970_3	3.26\|610754\|37\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610754-610790	37	MH937506	Streptococcus phage CHPC1148, complete genome	35552-35588	1	0.973
NZ_CP045970_3	3.26\|610754\|37\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610754-610790	37	KY705253	Streptococcus phage P0093, complete genome	32631-32667	1	0.973
NZ_CP045970_3	3.26\|610754\|37\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610754-610790	37	KY705254	Streptococcus phage P0094, complete genome	31034-31070	1	0.973
NZ_CP045970_3	3.6\|609459\|36\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	609459-609494	36	KJ094023	Listeria phage LP-101, complete genome	27001-27036	2	0.944
NZ_CP045970_3	3.17\|610169\|36\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610169-610204	36	KP399678	Listeria phage vB_LmoS_293, complete genome	1049-1084	2	0.944
NZ_CP045970_3	3.26\|610754\|37\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610754-610790	37	MN689509	Lactococcus phage CHPC1175, complete genome	29544-29580	2	0.946
NZ_CP045970_3	3.26\|610754\|37\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610754-610790	37	MK448735	Streptococcus phage Javan349, complete genome	11483-11519	2	0.946
NZ_CP045970_3	3.1\|609134\|36\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	609134-609169	36	NZ_LR134403	Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence	228347-228382	3	0.917
NZ_CP045970_3	3.16\|610104\|36\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610104-610139	36	MH341453	Listeria phage PSU-VKH-LP041, complete genome	41996-42031	3	0.917
NZ_CP045970_3	3.16\|610104\|36\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610104-610139	36	KJ094023	Listeria phage LP-101, complete genome	32760-32795	5	0.861
NZ_CP045970_3	3.14\|609978\|34\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	609978-610011	34	NC_022111	Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence	1764851-1764884	6	0.824
NZ_CP045970_3	3.27\|610820\|35\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610820-610854	35	MN694189	Marine virus AFVG_250M578, complete genome	47879-47913	6	0.829
NZ_CP045970_3	3.14\|609978\|34\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	609978-610011	34	NZ_CP038863	Campylobacter jejuni strain SCJK2 plasmid unnamed1, complete sequence	39302-39335	9	0.735
NZ_CP045970_3	3.18\|610234\|35\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610234-610268	35	NC_014533	Gloeothece verrucosa PCC 7822 plasmid Cy782201, complete sequence	491525-491559	9	0.743
NZ_CP045970_3	3.27\|610820\|35\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610820-610854	35	MK448625	Streptococcus satellite phage Javan738, complete genome	5960-5994	9	0.743
NZ_CP045970_3	3.27\|610820\|35\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610820-610854	35	MK448449	Streptococcus satellite phage Javan356, complete genome	4490-4524	9	0.743
NZ_CP045970_3	3.27\|610820\|35\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610820-610854	35	MK448636	Streptococcus satellite phage Javan749, complete genome	6112-6146	9	0.743
NZ_CP045970_3	3.27\|610820\|35\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610820-610854	35	NZ_CP045037	Lactobacillus mali strain LM596 plasmid unnamed2, complete sequence	34734-34768	9	0.743
NZ_CP045970_3	3.27\|610820\|35\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610820-610854	35	NZ_CP018177	Lactobacillus hordei strain TMW 1.1822 plasmid pL11822-1, complete sequence	11325-11359	9	0.743
NZ_CP045970_3	3.27\|610820\|35\|NZ_CP045970\|PILER-CR,CRISPRCasFinder,CRT	610820-610854	35	NZ_CP018181	Lactobacillus nagelii strain TMW 1.1827 plasmid pL11827-1, complete sequence	63608-63642	9	0.743

1. spacer 3.11|609784|36|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to NC_003216 (Listeria phage A118, complete genome) position: , mismatch: 0, identity: 1.0

ctggttactcaactggcgacagtaatacacctcaat	CRISPR spacer
ctggttactcaactggcgacagtaatacacctcaat	Protospacer
************************************

2. spacer 3.11|609784|36|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to AJ242593 (Bacteriophage A118 complete genome) position: , mismatch: 0, identity: 1.0

ctggttactcaactggcgacagtaatacacctcaat	CRISPR spacer
ctggttactcaactggcgacagtaatacacctcaat	Protospacer
************************************

3. spacer 3.15|610041|34|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to NC_003216 (Listeria phage A118, complete genome) position: , mismatch: 0, identity: 1.0

agaagcgttagcggcattgttcgaaagtaattta	CRISPR spacer
agaagcgttagcggcattgttcgaaagtaattta	Protospacer
**********************************

4. spacer 3.15|610041|34|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to AJ242593 (Bacteriophage A118 complete genome) position: , mismatch: 0, identity: 1.0

agaagcgttagcggcattgttcgaaagtaattta	CRISPR spacer
agaagcgttagcggcattgttcgaaagtaattta	Protospacer
**********************************

5. spacer 3.6|609459|36|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011399 (Listeria monocytogenes strain CFSAN008100 plasmid pCFSAN008100, complete sequence) position: , mismatch: 1, identity: 0.972

cgcttcacgttggtttttcgtagcccaattgctaaa	CRISPR spacer
cgcttcacgttgatttttcgtagcccaattgctaaa	Protospacer
************.***********************

6. spacer 3.6|609459|36|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 1, identity: 0.972

cgcttcacgttggtttttcgtagcccaattgctaaa	CRISPR spacer
cgcttcacgttgatttttcgtagcccaattgctaaa	Protospacer
************.***********************

7. spacer 3.25|610689|36|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to NC_021539 (Listeria phage LP-030-2, complete genome) position: , mismatch: 1, identity: 0.972

acgtttgcggtagttttaccgggcacggtcaaatat	CRISPR spacer
acgttcgcggtagttttaccgggcacggtcaaatat	Protospacer
*****.******************************

8. spacer 3.25|610689|36|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to AJ312240 (Bacteriophage PSA complete genome) position: , mismatch: 1, identity: 0.972

acgtttgcggtagttttaccgggcacggtcaaatat	CRISPR spacer
acgttcgcggtagttttaccgggcacggtcaaatat	Protospacer
*****.******************************

9. spacer 3.26|610754|37|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to KY705255 (Streptococcus phage P0095, complete genome) position: , mismatch: 1, identity: 0.973

caaaacagagaacgcgtgttcattatcggacatctta	CRISPR spacer
caaaacagagaacgagtgttcattatcggacatctta	Protospacer
************** **********************

10. spacer 3.26|610754|37|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to KY705251 (Streptococcus phage P0091, complete genome) position: , mismatch: 1, identity: 0.973

caaaacagagaacgcgtgttcattatcggacatctta	CRISPR spacer
caaaacagagaacgagtgttcattatcggacatctta	Protospacer
************** **********************

11. spacer 3.26|610754|37|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to KX879643 (Streptococcus phage CHPC1151, complete genome) position: , mismatch: 1, identity: 0.973

caaaacagagaacgcgtgttcattatcggacatctta	CRISPR spacer
caaaacagagaacgagtgttcattatcggacatctta	Protospacer
************** **********************

12. spacer 3.26|610754|37|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to MK202161 (Streptococcus phage CHPC1282, complete genome) position: , mismatch: 1, identity: 0.973

caaaacagagaacgcgtgttcattatcggacatctta	CRISPR spacer
caaaacagagaacgagtgttcattatcggacatctta	Protospacer
************** **********************

13. spacer 3.26|610754|37|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to KY705252 (Streptococcus phage P0092, complete genome) position: , mismatch: 1, identity: 0.973

caaaacagagaacgcgtgttcattatcggacatctta	CRISPR spacer
caaaacagagaacgagtgttcattatcggacatctta	Protospacer
************** **********************

14. spacer 3.26|610754|37|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to MH937506 (Streptococcus phage CHPC1148, complete genome) position: , mismatch: 1, identity: 0.973

caaaacagagaacgcgtgttcattatcggacatctta	CRISPR spacer
caaaacagagaacgagtgttcattatcggacatctta	Protospacer
************** **********************

15. spacer 3.26|610754|37|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to KY705253 (Streptococcus phage P0093, complete genome) position: , mismatch: 1, identity: 0.973

caaaacagagaacgcgtgttcattatcggacatctta	CRISPR spacer
caaaacagagaacgagtgttcattatcggacatctta	Protospacer
************** **********************

16. spacer 3.26|610754|37|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to KY705254 (Streptococcus phage P0094, complete genome) position: , mismatch: 1, identity: 0.973

caaaacagagaacgcgtgttcattatcggacatctta	CRISPR spacer
caaaacagagaacgagtgttcattatcggacatctta	Protospacer
************** **********************

17. spacer 3.6|609459|36|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 2, identity: 0.944

cgcttcacgttggtttttcgtagcccaattgctaaa	CRISPR spacer
cgcttcacgttgattttttgtagcccaattgctaaa	Protospacer
************.*****.*****************

18. spacer 3.17|610169|36|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to KP399678 (Listeria phage vB_LmoS_293, complete genome) position: , mismatch: 2, identity: 0.944

ctcataaggatttcgaggcgggttaaacgacatgta	CRISPR spacer
ctcataaggattgcgaggcgggttaaatgacatgta	Protospacer
************ **************.********

19. spacer 3.26|610754|37|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to MN689509 (Lactococcus phage CHPC1175, complete genome) position: , mismatch: 2, identity: 0.946

caaaacagagaacgcgtgttcattatcggacatctta	CRISPR spacer
caaaaccgagaacgtgtgttcattatcggacatctta	Protospacer
****** *******.**********************

20. spacer 3.26|610754|37|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to MK448735 (Streptococcus phage Javan349, complete genome) position: , mismatch: 2, identity: 0.946

caaaacagagaacgcgtgttcattatcggacatctta	CRISPR spacer
caaaacagagaacgggtgttcattgtcggacatctta	Protospacer
************** *********.************

21. spacer 3.1|609134|36|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR134403 (Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence) position: , mismatch: 3, identity: 0.917

aaagaccttcgatttcattctcactttccagttaat	CRISPR spacer
gaaaaccttcgatttcattcttactttccagttaat	Protospacer
.**.*****************.**************

22. spacer 3.16|610104|36|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to MH341453 (Listeria phage PSU-VKH-LP041, complete genome) position: , mismatch: 3, identity: 0.917

tataaaatattgcccaatgtgcggaaggagtttgga	CRISPR spacer
tataaaatattgtccaatgtgtggaaggagtttggg	Protospacer
************.********.*************.

23. spacer 3.16|610104|36|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 5, identity: 0.861

tataaaatattgcccaatgtgcggaaggagtttgga	CRISPR spacer
cattgaattttgcccaatgtgcggaaggagcttgga	Protospacer
.** .*** *********************.*****

24. spacer 3.14|609978|34|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to NC_022111 (Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence) position: , mismatch: 6, identity: 0.824

agaaaaaaaacatctttccaatttgttgttttgc	CRISPR spacer
agcaaaaaaacatctttcctatttgttttatcac	Protospacer
** **************** ******* * *..*

25. spacer 3.27|610820|35|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to MN694189 (Marine virus AFVG_250M578, complete genome) position: , mismatch: 6, identity: 0.829

ttttgaaatatgaggacttagaaaatgaaaaaaat	CRISPR spacer
taataaaaaatgagggcttagaaaatgaaaaaatt	Protospacer
*  *.*** ******.***************** *

26. spacer 3.14|609978|34|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038863 (Campylobacter jejuni strain SCJK2 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.735

agaaaaaaaacatctttccaatttgttgttttgc-----	CRISPR spacer
aagaaaaaaacatatttccaatt-----ttttccaaaaa	Protospacer
*..********** *********     **** *

27. spacer 3.18|610234|35|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to NC_014533 (Gloeothece verrucosa PCC 7822 plasmid Cy782201, complete sequence) position: , mismatch: 9, identity: 0.743

gcttttttcaacaattttatcaccagatgtcatta	CRISPR spacer
agttttttcaacaattttatgaacagataattttt	Protospacer
. ****************** * *****. . **

28. spacer 3.27|610820|35|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to MK448625 (Streptococcus satellite phage Javan738, complete genome) position: , mismatch: 9, identity: 0.743

ttttgaaatatgaggacttagaaaatgaaaaaaat	CRISPR spacer
gtatgaactatgaggacttagaaagtgaagacctg	Protospacer
 * **** ****************.****.*

29. spacer 3.27|610820|35|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to MK448449 (Streptococcus satellite phage Javan356, complete genome) position: , mismatch: 9, identity: 0.743

ttttgaaatatgaggacttagaaaatgaaaaaaat	CRISPR spacer
gtatgaactatgaggacttagaaagtgaagacctg	Protospacer
 * **** ****************.****.*

30. spacer 3.27|610820|35|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to MK448636 (Streptococcus satellite phage Javan749, complete genome) position: , mismatch: 9, identity: 0.743

ttttgaaatatgaggacttagaaaatgaaaaaaat	CRISPR spacer
gtctgaactatgaggacttagaaagtgaagacctg	Protospacer
 *.**** ****************.****.*

31. spacer 3.27|610820|35|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045037 (Lactobacillus mali strain LM596 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.743

ttttgaaatatgaggacttagaaaatgaaaaaaat	CRISPR spacer
ttaagaaatataaggacttagtaaatgaagttatg	Protospacer
**  *******.********* *******.  *

32. spacer 3.27|610820|35|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018177 (Lactobacillus hordei strain TMW 1.1822 plasmid pL11822-1, complete sequence) position: , mismatch: 9, identity: 0.743

ttttgaaatatgaggacttagaaaatgaaaaaaat	CRISPR spacer
ttaagaaatataaggacttagtaaatgaagttatg	Protospacer
**  *******.********* *******.  *

33. spacer 3.27|610820|35|NZ_CP045970|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018181 (Lactobacillus nagelii strain TMW 1.1827 plasmid pL11827-1, complete sequence) position: , mismatch: 9, identity: 0.743

ttttgaaatatgaggacttagaaaatgaaaaaaat	CRISPR spacer
ttaagaaatataaggacttagtaaatgaagttatg	Protospacer
**  *******.********* *******.  *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

125389 : 131914

Listeria_phage(33.33%)

tail

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003721739.1\|125389_125842_-	ImmA/IrrE family metallo-endopeptidase	A0A059T7S0	Listeria_phage	4.0e-31	47.9
WP_003721740.1\|125847_126183_-	helix-turn-helix transcriptional regulator	A0A2H4JAR9	uncultured_Caudovirales_phage	4.0e-20	52.5
WP_003732219.1\|126399_126828_+	hypothetical protein	NA	NA	NA	NA
WP_003732220.1\|126839_127256_+	hypothetical protein	A8ASQ1	Listeria_phage	1.3e-20	39.3
WP_003733902.1\|127533_127923_+	DUF5072 domain-containing protein	NA	NA	NA	NA
WP_003721744.1\|127935_128448_+\|tail	phage major tail protein, TP901-1 family	A0A097PBF4	Streptococcus_pyogenes_phage	1.2e-47	62.7
WP_003721745.1\|128495_128798_+	hypothetical protein	NA	NA	NA	NA
WP_072217178.1\|128839_129244_+	phenylalanine racemase	NA	NA	NA	NA
WP_061112172.1\|129230_131099_+	hypothetical protein	A0A097PAU2	Streptococcus_pyogenes_phage	3.5e-20	45.8
WP_057171696.1\|131095_131914_+\|tail	phage tail family protein	A0A060AFE1	Staphylococcus_phage	2.5e-39	35.0

DBSCAN-SWA_2

1183158 : 1192116

Hokovirus(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003721506.1\|1183158_1183542_+	glycerol-3-phosphate cytidylyltransferase	A0A1V0SGE7	Hokovirus	1.4e-16	40.7
WP_003721507.1\|1183563_1184547_+	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	3.1e-12	35.3
WP_010989660.1\|1184561_1185575_+	glycosyltransferase	A0A1V0SAH6	Catovirus	7.9e-11	32.0
WP_003721509.1\|1185783_1187274_+	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	9.5e-114	49.7
WP_033918355.1\|1187285_1188110_+	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	9.7e-68	52.9
WP_003721511.1\|1188122_1188431_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_003721512.1\|1188490_1188895_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_154079549.1\|1189023_1190580_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	3.9e-17	28.1
WP_033918357.1\|1190712_1192116_+	hypothetical protein	Q38324	Lactococcus_phage	1.7e-16	25.4

DBSCAN-SWA_3

1324358 : 1383926

Bacillus_virus(16.67%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003723562.1\|1324358_1325498_-\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_003723563.1\|1325578_1325974_-	helix-turn-helix transcriptional regulator	A9D9J6	Lactobacillus_prophage	1.3e-14	57.4
WP_003727524.1\|1326124_1326340_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003732794.1\|1326458_1326992_+\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_003732795.1\|1327009_1327675_+	hypothetical protein	NA	NA	NA	NA
WP_003732796.1\|1327936_1328875_+	hypothetical protein	NA	NA	NA	NA
WP_003723884.1\|1328989_1330273_+	trigger factor	NA	NA	NA	NA
WP_003723886.1\|1330458_1331718_+\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.4e-145	63.2
WP_003723887.1\|1331836_1332403_+	type I signal peptidase SipX	NA	NA	NA	NA
WP_003723888.1\|1332437_1333007_+	type I signal peptidase SipY	NA	NA	NA	NA
WP_003723889.1\|1333108_1333651_+	type I signal peptidase SipZ	NA	NA	NA	NA
WP_003723890.1\|1333660_1334524_+	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_003723891.1\|1334520_1335306_+	ribonuclease HII	G4YAY0	Emiliania_huxleyi_virus	3.0e-26	39.2
WP_003723892.1\|1335439_1336300_+	DNA-protecting protein DprA	NA	NA	NA	NA
WP_003732799.1\|1336570_1338649_+	type I DNA topoisomerase	A0A1V0SB35	Catovirus	3.2e-107	37.5
WP_003723999.1\|1338711_1340016_+\|tRNA	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	NA	NA	NA	NA
WP_003724000.1\|1340298_1341201_+	tyrosine recombinase XerC	A0A097EYL9	Mycobacterium_phage	1.2e-13	28.6
WP_003724001.1\|1341221_1341761_+\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_003732800.1\|1341774_1343184_+\|protease	ATP-dependent protease ATPase subunit HslU	W6AS21	Erwinia_phage	3.7e-43	28.7
WP_003726695.1\|1343204_1343984_+	GTP-sensing pleiotropic transcriptional regulator CodY	NA	NA	NA	NA
WP_003724129.1\|1344086_1344506_+	acyl-CoA thioesterase	NA	NA	NA	NA
WP_003724130.1\|1344527_1344839_+	hypothetical protein	NA	NA	NA	NA
WP_003724131.1\|1344841_1345714_+	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_003724132.1\|1345755_1346352_-	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_003732802.1\|1346509_1346917_+	CoA-binding protein	NA	NA	NA	NA
WP_003723731.1\|1347097_1349065_+	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	6.7e-123	42.5
WP_003723732.1\|1349061_1351521_+	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	1.1e-101	31.6
WP_003723733.1\|1351603_1352071_+	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_097296616.1\|1352400_1354254_+	lmo1289 family class 1 internalin	NA	NA	NA	NA
WP_003723735.1\|1354585_1356388_+	class 1 internalin InlK	NA	NA	NA	NA
WP_003723736.1\|1356421_1358290_-	acetyltransferase	B5WZU0	Pseudomonas_phage	6.5e-43	31.9
WP_003723737.1\|1358502_1359201_+	glycerophosphodiester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	1.3e-12	32.4
WP_003723738.1\|1359433_1361110_+	glycerol-3-phosphate dehydrogenase/oxidase	NA	NA	NA	NA
WP_003723739.1\|1361235_1362153_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_003719566.1\|1362275_1362509_+	RNA chaperone Hfq	NA	NA	NA	NA
WP_003733804.1\|1362619_1363843_+	GTPase HflX	NA	NA	NA	NA
WP_003723434.1\|1363835_1365062_+	methionine gamma-lyase family protein	NA	NA	NA	NA
WP_003719570.1\|1365265_1365634_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_003723435.1\|1365704_1367039_+	type I glutamate--ammonia ligase	A0A1V0SJ53	Klosneuvirus	2.0e-06	26.4
WP_033918375.1\|1367182_1368478_+	arsenical efflux pump membrane protein ArsB	A0A2H4PQU3	Staphylococcus_phage	1.8e-145	61.9
WP_003723437.1\|1368521_1369043_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003723438.1\|1369072_1369687_-	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	9.3e-15	62.1
WP_003723439.1\|1369843_1370173_+	cell division suppressor protein YneA	NA	NA	NA	NA
WP_003723440.1\|1370264_1370492_+	DUF896 domain-containing protein	NA	NA	NA	NA
WP_003723441.1\|1370638_1372633_+	transketolase	NA	NA	NA	NA
WP_003723442.1\|1372853_1373093_+	YneF family protein	NA	NA	NA	NA
WP_003723443.1\|1373143_1373986_-	DUF2785 domain-containing protein	NA	NA	NA	NA
WP_003723444.1\|1374004_1374736_-	class I SAM-dependent methyltransferase	A0A1X9I6N4	Streptococcus_phage	1.2e-80	59.1
WP_003723445.1\|1374757_1375264_-	ParB-like nuclease domain-containing protein	A0A220GKT8	Streptococcus_phage	4.0e-56	66.7
WP_003723446.1\|1375273_1376578_-	DUF3440 domain-containing protein	A0A220GKF8	Streptococcus_phage	9.5e-134	52.1
WP_072217143.1\|1376567_1377773_-	helicase SNF2	L0P6E9	Lactobacillus_phage	3.7e-92	47.1
WP_003723448.1\|1377750_1378125_-	hypothetical protein	NA	NA	NA	NA
WP_003723449.1\|1378417_1379146_+	UMP kinase	NA	NA	NA	NA
WP_003723450.1\|1379145_1379703_+	ribosome recycling factor	NA	NA	NA	NA
WP_003723451.1\|1379932_1380691_+	isoprenyl transferase	R9W0U9	Flavobacterium_phage	1.1e-22	41.4
WP_003723452.1\|1380704_1381493_+	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_003723453.1\|1381507_1382650_+	1-deoxy-D-xylulose-5-phosphate reductoisomerase	NA	NA	NA	NA
WP_003723454.1\|1382663_1383926_+\|protease	RIP metalloprotease RseP	NA	NA	NA	NA

DBSCAN-SWA_4

1875183 : 1883469

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003722243.1\|1875183_1875750_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	7.0e-25	35.9
WP_003722244.1\|1875746_1876796_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.0e-61	43.2
WP_003722245.1\|1876814_1878242_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.1e-53	34.6
WP_003722246.1\|1878226_1880446_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.6e-160	41.4
WP_003722247.1\|1880438_1881122_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_003722248.1\|1881125_1881371_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_003722249.1\|1881382_1882096_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3F9V5	Synechococcus_phage	2.7e-42	38.7
WP_003722250.1\|1882176_1883469_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	7.2e-17	32.6

DBSCAN-SWA_5

2398928 : 2437760

Listeria_phage(93.18%)

terminase,tail,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_154079555.1\|2398928_2399378_+	hypothetical protein	Q9T196	Listeria_phage	3.4e-59	79.9
WP_039120634.1\|2399458_2399848_-	hypothetical protein	NA	NA	NA	NA
WP_154079556.1\|2399844_2400198_-	hypothetical protein	NA	NA	NA	NA
WP_061112563.1\|2400194_2400713_-	hypothetical protein	NA	NA	NA	NA
WP_154079557.1\|2401120_2401324_-	hypothetical protein	NA	NA	NA	NA
WP_154079558.1\|2401447_2402290_-	M15 family peptidase	A0A059T7Y8	Listeria_phage	2.0e-132	85.5
WP_012951558.1\|2402289_2402547_-\|holin	phage holin	A8ATB7	Listeria_phage	3.2e-25	69.0
WP_064614890.1\|2402546_2402849_-	hypothetical protein	A0A059T5E6	Listeria_phage	7.7e-39	94.0
WP_064614892.1\|2402899_2405065_-	hypothetical protein	A8ATW1	Listeria_phage	0.0e+00	92.4
WP_003745022.1\|2405077_2406646_-	hypothetical protein	A8ATW0	Listeria_phage	2.2e-302	98.5
WP_154079559.1\|2406642_2411433_-\|tail	phage tail tape measure protein	A8ATV9	Listeria_phage	0.0e+00	87.4
WP_154079560.1\|2411437_2411749_-	hypothetical protein	A0A0B5D116	Listeria_phage	1.6e-39	92.3
WP_061107467.1\|2411745_2412177_-	hypothetical protein	A0A0B5D0B8	Listeria_phage	1.6e-69	94.4
WP_033533848.1\|2412232_2412919_-	Ig domain-containing protein	A0A0B5CYK8	Listeria_phage	4.4e-114	97.8
WP_154079561.1\|2412923_2413295_-	hypothetical protein	A0A0B5CTY4	Listeria_phage	5.5e-63	99.2
WP_031672311.1\|2413291_2413609_-	HK97 gp10 family phage protein	A0A0B5CTS1	Listeria_phage	2.0e-53	100.0
WP_014930192.1\|2413598_2413964_-	hypothetical protein	A0A0B5D114	Listeria_phage	1.5e-65	100.0
WP_031672309.1\|2413963_2414317_-	hypothetical protein	A0A0B5D0B3	Listeria_phage	1.7e-61	100.0
WP_033533849.1\|2414486_2415359_-	hypothetical protein	A0A0B5CTX8	Listeria_phage	4.5e-164	100.0
WP_070777299.1\|2415381_2415936_-	hypothetical protein	A8ATU9	Listeria_phage	3.3e-88	98.9
WP_003719493.1\|2416032_2417076_-	gp4	A0A0B5D111	Listeria_phage	9.7e-198	98.3
WP_070213813.1\|2417080_2418640_-	hypothetical protein	A8ATU7	Listeria_phage	9.2e-293	97.1
WP_077947132.1\|2418654_2419974_-\|terminase	PBSX family phage terminase large subunit	A0A0B5CYJ6	Listeria_phage	4.2e-254	94.5
WP_003733714.1\|2419966_2420707_-	hypothetical protein	A8ATU5	Listeria_phage	7.0e-134	98.8
WP_003725074.1\|2420746_2420974_-	hypothetical protein	A0A0B5CTV3	Listeria_phage	1.8e-32	94.7
WP_154079562.1\|2421234_2421807_-	sigma-70 family RNA polymerase sigma factor	A0A0B5D145	Listeria_phage	6.7e-92	89.5
WP_003734975.1\|2421894_2422050_-	DUF3954 domain-containing protein	A0A0B5D0E9	Listeria_phage	1.1e-22	98.0
WP_154079563.1\|2422194_2422599_-	hypothetical protein	A8AU00	Listeria_phage	1.0e-70	97.8
WP_003759675.1\|2422564_2422705_-	BH0509 family protein	A8ATZ9	Listeria_phage	4.7e-15	87.0
WP_039382681.1\|2422701_2423007_-	hypothetical protein	A8ATZ8	Listeria_phage	1.9e-37	83.2
WP_154079564.1\|2423034_2423412_-	hypothetical protein	NA	NA	NA	NA
WP_154079565.1\|2423434_2423917_-	single-stranded DNA-binding protein	A8ATZ7	Listeria_phage	1.8e-58	75.6
WP_003769969.1\|2423913_2424237_-	hypothetical protein	A0A059T801	Listeria_phage	1.7e-44	90.8
WP_154079566.1\|2424217_2424460_-	hypothetical protein	NA	NA	NA	NA
WP_038409808.1\|2424456_2424978_-	hypothetical protein	A8ASP2	Listeria_phage	1.6e-92	96.5
WP_038409807.1\|2424974_2425163_-	hypothetical protein	D7RWG4	Brochothrix_phage	4.4e-08	47.2
WP_077913500.1\|2425166_2425538_-	hypothetical protein	R4ICD6	Listeria_phage	1.2e-38	100.0
WP_038409806.1\|2425534_2425903_-	hypothetical protein	A8ASN9	Listeria_phage	6.5e-64	95.9
WP_038409805.1\|2425899_2426496_-	DUF1642 domain-containing protein	A8ATY9	Listeria_phage	3.1e-39	48.5
WP_003722560.1\|2426492_2427305_-	DNA adenine methylase	Q8W5X3	Listeria_phage	4.8e-152	95.6
WP_009924222.1\|2427301_2428213_-	DnaD domain-containing protein	A0A0B5D175	Listeria_phage	2.2e-137	89.5
WP_009924223.1\|2428250_2429162_-	recombinase RecT	NA	NA	NA	NA
WP_154079567.1\|2429154_2430666_-	ATPase	A0A2I7SC81	Paenibacillus_phage	5.6e-69	33.5
WP_003733629.1\|2430898_2431087_-	hypothetical protein	Q9T175	Listeria_phage	1.2e-21	80.6
WP_154079568.1\|2431194_2431410_-	hypothetical protein	Q9T176	Listeria_phage	7.7e-25	84.5
WP_154079569.1\|2431402_2431939_-	hypothetical protein	A0A059T5F0	Listeria_phage	2.5e-80	89.0
WP_154079570.1\|2432061_2432835_-	phage regulatory protein	R9QMT9	Lactococcus_phage	3.6e-40	41.1
WP_154079571.1\|2432836_2433034_-	hypothetical protein	NA	NA	NA	NA
WP_154079581.1\|2433050_2433227_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_154079572.1\|2433453_2433936_+	helix-turn-helix domain-containing protein	A8ASM2	Listeria_phage	1.7e-27	50.4
WP_003747292.1\|2434092_2434260_+	hypothetical protein	NA	NA	NA	NA
WP_003747290.1\|2434315_2434534_+	hypothetical protein	A0A059T6E3	Listeria_phage	2.4e-26	81.9
WP_003733640.1\|2434549_2435272_+	hypothetical protein	A0A059T7P9	Listeria_phage	2.8e-103	97.9
WP_003733641.1\|2435294_2435900_+	hypothetical protein	NA	NA	NA	NA
WP_003749252.1\|2435912_2436335_+	hypothetical protein	NA	NA	NA	NA
WP_154079573.1\|2436401_2437760_+	recombinase family protein	Q8LTD8	Listeria_phage	3.1e-236	89.6

DBSCAN-SWA_6

2592078 : 2599922

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003722604.1\|2592078_2593050_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	5.2e-52	39.4
WP_003722605.1\|2593057_2594026_-	YvcK family protein	A1IMD5	Streptococcus_phage	6.7e-68	43.3
WP_003722606.1\|2594027_2594903_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.9e-08	29.7
WP_033918280.1\|2595010_2596741_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	3.0e-175	54.0
WP_003734087.1\|2596782_2597844_-	galactose mutarotase	NA	NA	NA	NA
WP_009924988.1\|2597860_2598844_-	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	2.6e-51	37.2
WP_003722610.1\|2598962_2599922_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.0e-88	53.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP045970

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection