CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NZ_CP045058	Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p2, complete sequence	0 crisprs	DEDDh	0	0	1
NZ_CP045059	Salmonella enterica subsp. enterica serovar Muenchen strain LG25 chromosome, complete genome	2 crisprs	DEDDh,WYL,DinG,cas3,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e	1	9	10
NZ_CP045057	Salmonella enterica subsp. enterica serovar Muenchen strain LG25 plasmid pLG25p1, complete sequence	0 crisprs	NA	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

24835 : 146397

Salmonella_phage(35.0%)

protease,holin,terminase,integrase,tail,head,capsid,transposase,lysis,plate,bacteriocin,portal

attL 25113:25129|attR 71708:71724

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_097361660.1\|24835_25510_-\|transposase	transposase	A0A0P0ZCV4	Stx2-converting_phage	5.2e-11	30.1
25113:25129	attL	NA	NA	NA	NA
WP_057393574.1\|26364_27261_+	antimicrobial resistance protein Mig-14	NA	NA	NA	NA
WP_139760138.1\|29100_30015_+	pyocin	NA	NA	NA	NA
WP_057395147.1\|30011_30284_+	hypothetical protein	NA	NA	NA	NA
WP_139760136.1\|30876_30990_+	hypothetical protein	A0A1C9IHU6	Salmonella_phage	1.4e-09	94.6
WP_057395148.1\|31025_31595_-\|tail	tail fiber assembly protein	A0A0M4RTP2	Salmonella_phage	8.4e-95	89.4
WP_097361583.1\|31594_32770_-\|tail	tail fiber protein	A0A0M3ULH6	Salmonella_phage	3.4e-50	80.3
WP_097361584.1\|32756_33344_-	DUF2313 domain-containing protein	A0A192Y5V3	Salmonella_phage	7.8e-112	97.9
WP_097361585.1\|33346_34426_-\|plate	baseplate J/gp47 family protein	A0A192Y6E4	Salmonella_phage	1.2e-198	95.8
WP_000605053.1\|34418_34832_-	hypothetical protein	A0A192Y6D0	Salmonella_phage	3.3e-72	94.9
WP_001273646.1\|34836_35370_-\|plate	phage baseplate assembly protein V	Q8HAB9	Salmonella_phage	1.0e-94	98.9
WP_097361587.1\|35369_36428_-\|plate	baseplate protein	A0A192Y7L7	Salmonella_phage	4.3e-201	99.1
WP_097361588.1\|36424_37765_-	DNA circularization protein	A0A192Y5U9	Salmonella_phage	5.3e-249	98.9
WP_000497739.1\|40932_41097_-	DUF2635 domain-containing protein	Q8HAC6	Salmonella_phage	1.0e-24	100.0
WP_000779212.1\|41100_41661_-	hypothetical protein	A0A192Y5U4	Salmonella_phage	3.7e-103	97.3
WP_079953067.1\|41657_42170_-	hypothetical protein	Q8HAC8	Salmonella_phage	8.1e-89	96.5
WP_000702382.1\|42141_42546_-\|head	phage head closure protein	A0A192Y6C2	Salmonella_phage	9.3e-64	88.1
WP_000927721.1\|42542_42866_-\|head,tail	phage gp6-like head-tail connector protein	U5P072	Shigella_phage	2.4e-54	97.2
WP_000601365.1\|42868_43069_-	hypothetical protein	S5FNU1	Shigella_phage	3.4e-27	100.0
WP_079781928.1\|43118_44324_-\|capsid	phage major capsid protein	A0A192Y5T6	Salmonella_phage	1.1e-221	98.5
WP_153789523.1\|44338_44989_-\|head,protease	HK97 family phage prohead protease	Q8HAD3	Salmonella_phage	1.5e-116	96.3
WP_000466255.1\|44966_46208_-\|portal	phage portal protein	U5P411	Shigella_phage	2.0e-242	99.8
WP_097361591.1\|46207_46390_-	hypothetical protein	Q8HAD5	Salmonella_phage	5.0e-25	98.3
WP_153789524.1\|46401_46542_-	hypothetical protein	Q8HAD6	Salmonella_phage	1.7e-17	97.8
WP_153789525.1\|46590_48135_-\|terminase	terminase large subunit	Q8HAD6	Salmonella_phage	7.4e-311	99.6
WP_079953069.1\|48131_48626_-\|terminase	phage terminase small subunit P27 family	Q8HAD7	Salmonella_phage	7.8e-89	99.4
WP_001135222.1\|48756_49107_-	HNH endonuclease	Q8SBD7	Shigella_phage	1.0e-63	96.6
WP_001292891.1\|49167_49470_-	hypothetical protein	Q8HA83	Salmonella_phage	5.1e-51	97.0
WP_000501908.1\|49546_49834_-	TonB family protein	H6WZK5	Escherichia_phage	7.6e-20	50.0
WP_001050801.1\|50011_50557_-	DUF2514 domain-containing protein	A0A291LBG9	Klebsiella_phage	2.8e-07	58.1
WP_001527046.1\|51170_51515_-\|holin	phage holin, lambda family	Q8HA87	Salmonella_phage	5.3e-44	100.0
WP_070801491.1\|52436_53249_+	DUF3800 domain-containing protein	Q19UP3	Mannheimia_phage	1.4e-63	47.0
WP_080198751.1\|53540_54356_-	antitermination protein	A0A1B5FPA5	Escherichia_phage	1.8e-106	74.2
WP_097361593.1\|54352_55213_-	helix-turn-helix domain containing protein	A0A1B5FPA6	Escherichia_phage	8.7e-128	80.6
WP_097361594.1\|55212_56181_-	DNA primase	A0A1B5FPA8	Escherichia_phage	7.0e-166	87.9
WP_097361595.1\|56177_57782_-	DEAD/DEAH box helicase	A0A1B5FPA4	Escherichia_phage	1.2e-274	85.4
WP_079953078.1\|58841_59498_+	LexA family transcriptional regulator	Q8W648	Enterobacteria_phage	1.8e-93	74.3
WP_000560246.1\|59638_59836_+	hypothetical protein	NA	NA	NA	NA
WP_097361596.1\|59838_60030_+	hypothetical protein	A0A1B5FPB5	Escherichia_phage	1.4e-09	53.2
WP_079953080.1\|60103_60298_+	hypothetical protein	NA	NA	NA	NA
WP_000155900.1\|60294_60480_+	hypothetical protein	NA	NA	NA	NA
WP_079916472.1\|60667_60877_+	hypothetical protein	NA	NA	NA	NA
WP_079953081.1\|60800_61217_+	hypothetical protein	A0A1B5FPB3	Escherichia_phage	7.2e-27	56.4
WP_097361597.1\|61216_61417_+	hypothetical protein	A0A1B5FPB7	Escherichia_phage	1.9e-14	71.7
WP_079953083.1\|61447_62353_+	ORF6N domain-containing protein	F1C5A3	Cronobacter_phage	2.9e-129	77.6
WP_070801904.1\|62349_62916_+	hypothetical protein	A0A088C4R7	Shewanella_sp._phage	1.8e-28	39.4
WP_079953084.1\|62912_63137_+	hypothetical protein	A0A1B5FPG2	Escherichia_phage	1.2e-17	65.8
WP_079953085.1\|63133_63598_+	ATPase	A0A1B5FPC7	Escherichia_phage	4.4e-41	51.7
WP_000202173.1\|63597_63813_+	hypothetical protein	A0A248XD10	Klebsiella_phage	1.6e-06	43.1
WP_070789913.1\|63963_64206_+	excisionase family protein	A0A286S2A4	Klebsiella_phage	1.1e-22	68.4
WP_097361598.1\|64231_65557_+\|integrase	site-specific integrase	Q20GI2	Phage_258-320	1.1e-164	64.5
WP_079953089.1\|66048_67599_-	HAMP domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	3.0e-09	32.9
WP_079953095.1\|71584_71998_+\|transposase	transposase	A0A0P0ZCV4	Stx2-converting_phage	5.8e-13	38.5
71708:71724	attR	NA	NA	NA	NA
WP_079953096.1\|71997_72318_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.3e-33	65.6
WP_097361599.1\|73343_74249_+	recombinase RecA	A0A0S2MVG1	Bacillus_phage	6.2e-84	58.8
WP_058644812.1\|74415_75504_+	quinol oxidase	NA	NA	NA	NA
WP_097361600.1\|76477_77680_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	8.9e-78	72.5
WP_079953100.1\|77619_77904_-	hypothetical protein	NA	NA	NA	NA
WP_097361601.1\|77932_78688_-	AAA family ATPase	K4HZD4	Acidithiobacillus_phage	3.8e-42	41.8
WP_097361602.1\|81923_84125_-	ferric aerobactin receptor IutA	NA	NA	NA	NA
WP_023247018.1\|84150_85485_-	NADPH-dependent L-lysine N(6)-monooxygenase	NA	NA	NA	NA
WP_097361603.1\|85488_87222_-	aerobactin synthase IucC	NA	NA	NA	NA
WP_097361604.1\|87221_88169_-	N(6)-hydroxylysine O-acetyltransferase	NA	NA	NA	NA
WP_153789526.1\|88169_89894_-	aerobactin synthase IucA	NA	NA	NA	NA
WP_097361605.1\|90026_91238_+	MFS transporter	NA	NA	NA	NA
WP_097361606.1\|91253_92141_+	siderophore-interacting protein	NA	NA	NA	NA
WP_023247011.1\|93846_94383_+	fimbrial protein	NA	NA	NA	NA
WP_079953106.1\|94508_95171_+	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_097361607.1\|95181_97728_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_097361662.1\|97858_98911_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_097361608.1\|99073_99526_+	C-lysozyme inhibitor	NA	NA	NA	NA
WP_057394607.1\|99665_100040_+	DUF1090 domain-containing protein	NA	NA	NA	NA
WP_047643234.1\|100223_100550_-	nucleoside transporter	NA	NA	NA	NA
WP_077917243.1\|100571_101198_-	ParB-like nuclease domain-containing protein	A0A0F7L444	uncultured_marine_virus	4.1e-50	50.5
WP_097361454.1\|101194_102424_-	DUF3440 domain-containing protein	A0A068F1U8	Mycobacterium_phage	1.7e-60	34.1
WP_097361455.1\|102417_103149_-	hypothetical protein	NA	NA	NA	NA
WP_097361456.1\|103138_103669_-	CaiF/GrlA family transcriptional regulator	NA	NA	NA	NA
WP_000984349.1\|104191_104662_-	DUF2919 family protein	NA	NA	NA	NA
WP_097361609.1\|112654_114451_-	ShlB/FhaC/HecB family hemolysin secretion/activation protein	NA	NA	NA	NA
WP_000493286.1\|115587_115917_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A088CBP5	Shigella_phage	2.4e-09	44.2
WP_057394952.1\|115897_116179_+	helix-turn-helix transcriptional regulator	A0A2I6TC97	Escherichia_phage	5.9e-09	39.1
WP_097361610.1\|117068_118820_+	colicin	NA	NA	NA	NA
WP_057394954.1\|118822_119086_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_057394955.1\|119169_119316_+\|lysis	lysis protein	NA	NA	NA	NA
WP_097361611.1\|119839_122836_-\|transposase	Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	64.2
WP_057393714.1\|122999_123572_+	recombinase family protein	Q1MVP4	Enterobacteria_phage	8.2e-82	86.8
WP_057393711.1\|123692_124145_+	N-acetyltransferase	NA	NA	NA	NA
WP_153789527.1\|124176_125709_-	SidA/IucD/PvdA family monooxygenase	NA	NA	NA	NA
WP_079953337.1\|125705_125975_-	hypothetical protein	NA	NA	NA	NA
WP_057394178.1\|127627_127900_+	hypothetical protein	NA	NA	NA	NA
WP_057393724.1\|130144_132247_+	TonB-dependent receptor	A0A0P0I887	Acinetobacter_phage	8.1e-10	34.6
WP_057393723.1\|132385_132994_+	recombinase family protein	A0A1S5Y2X8	uncultured_archaeal_virus	1.2e-17	33.9
WP_057393721.1\|133482_133827_+	hypothetical protein	NA	NA	NA	NA
WP_097361613.1\|135134_136282_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	4.3e-146	92.2
WP_153789528.1\|136342_136615_-\|bacteriocin	colicin-V (microcin-V bacteriocin)	NA	NA	NA	NA
WP_139760163.1\|136885_139000_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	2.7e-37	27.8
WP_097361615.1\|138974_140216_-	HlyD family secretion protein	NA	NA	NA	NA
WP_097361663.1\|140873_142424_-	MchC protein	NA	NA	NA	NA
WP_057393929.1\|145704_146397_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP045059

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP045059_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045059_1

3002213-3003340

TypeI-E

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRT
CCGGTTTATCCCCGCTGGCGCGGGGAACAC	PILER-CR
CGGTTTATCCCCGCTGGCGCGGGGAACAC	PILER-CR

18 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP045059_1

>merge|NZ_CP045059|1|3002213-3003340|CRISPRCasFinder,CRT,PILER-CR,PILER-CR
GTGTTTATCCCCGCTGACGCGGGGAACACGATTTTTCGCCAGCCACTCCAGCCAGTGCTGCCGGTTTATCCCCGCTGGCGCGGGGAACACTAGCAATGGAAATATTTGCATGGATAGTTGCGCGGTTTATCCCCGCTGGCGCGGGGAACACATCGCCGGGGCGGGCAATGACGCCAGCTCACCCGGTTTATCCCCGCTGGCGCGGGGAACACCCCCCCTGATTATTTTTTATCCGTTTCAGTAACGGTTTATCCCCGCTGGCGCGGGGAACACCCGAAACCCGCTATAACGAATAACAGTGCTCACGGTTTATCCCCGCTGGCGCGGGGAACACTGATCAGGAGTGCCGCCGATAACAGCCAGAATCGGTTTATCCCCGCTGGCGCGGGGAACACGTCTGGGGACATTCACCTGCATGACCTTGAGGCCGGTTTATCCCCGCTGGCGCGGGGAACACAACACGGCGGCAATATCGCGCCCCTGACTGGGCGGTTTATCCCCGCTGGCGCGGGGAACACAACACGGCGGCAATATCGCGCCCCTGACTGGGCGGTTTATCCCCGCTGGCGCGGGGAACACCCCCGAGCTACCGCCAGGACTTATTGAAGTGACGGTTTATCCCCGCTGGCGCGGGGAACACGCAAACAAACTGCGGTTTTATGGCTCGCTGAACGGTTTATCCCCGCTGGCGCGGGGAACACACAAACATTGCAGCTACGTTAATTGGATCAATCGGTTTATCCCCGCTGGCGCGGGGAACACGCAAACGGGCTCATTTTCCACTGCGCGGCCTGCGGTTTATCCCCGCTGGCGCGGGGAACACCTGCGCGACAACTTCATCGAACAGGTCACAGGCGGTTTATCCCCGCTGGCGCGGGGAACACCGCTACGCAGTCCGCGAGAATATCCTGCGCACCGGTTTATCCCCGCTGGCGCGGGGAACACTCGTCGAGGCGGATGAAATAGTGGTTAGCATCCGGTTTATCCCCGCTGGCGCGGGGAACACAGCGCCAGGGAACCGGTTAAACCCTGTGTTGCCGGTTTATCCCCGCTGGCGCGGGGAACACGTTCTCAGGGGTTGGATTGTTAACGCTGCCAACGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP045059|1|1|3002213-3003340|CRISPRCasFinder
GTGTTTATCCCCGCTGACGCGGGGAACAC	GATTTTTCGCCAGCCACTCCAGCCAGTGCTGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TAGCAATGGAAATATTTGCATGGATAGTTGCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATCGCCGGGGCGGGCAATGACGCCAGCTCACC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCCCCCTGATTATTTTTTATCCGTTTCAGTAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCGAAACCCGCTATAACGAATAACAGTGCTCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGATCAGGAGTGCCGCCGATAACAGCCAGAAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCTGGGGACATTCACCTGCATGACCTTGAGGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AACACGGCGGCAATATCGCGCCCCTGACTGGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AACACGGCGGCAATATCGCGCCCCTGACTGGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCCCGAGCTACCGCCAGGACTTATTGAAGTGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCAAACAAACTGCGGTTTTATGGCTCGCTGAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACAAACATTGCAGCTACGTTAATTGGATCAAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCAAACGGGCTCATTTTCCACTGCGCGGCCTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CTGCGCGACAACTTCATCGAACAGGTCACAGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CGCTACGCAGTCCGCGAGAATATCCTGCGCAC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TCGTCGAGGCGGATGAAATAGTGGTTAGCATC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGCGCCAGGGAACCGGTTAAACCCTGTGTTGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTTCTCAGGGGTTGGATTGTTAACGCTGCCAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP045059|1|1|3002213-3003340|CRT
GTGTTTATCCCCGCTGACGCGGGGAACAC	GATTTTTCGCCAGCCACTCCAGCCAGTGCTGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TAGCAATGGAAATATTTGCATGGATAGTTGCG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ATCGCCGGGGCGGGCAATGACGCCAGCTCACC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCCCCCTGATTATTTTTTATCCGTTTCAGTAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCGAAACCCGCTATAACGAATAACAGTGCTCA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TGATCAGGAGTGCCGCCGATAACAGCCAGAAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCTGGGGACATTCACCTGCATGACCTTGAGGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AACACGGCGGCAATATCGCGCCCCTGACTGGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AACACGGCGGCAATATCGCGCCCCTGACTGGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCCCGAGCTACCGCCAGGACTTATTGAAGTGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCAAACAAACTGCGGTTTTATGGCTCGCTGAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACAAACATTGCAGCTACGTTAATTGGATCAAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCAAACGGGCTCATTTTCCACTGCGCGGCCTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CTGCGCGACAACTTCATCGAACAGGTCACAGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CGCTACGCAGTCCGCGAGAATATCCTGCGCAC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TCGTCGAGGCGGATGAAATAGTGGTTAGCATC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGCGCCAGGGAACCGGTTAAACCCTGTGTTGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTTCTCAGGGGTTGGATTGTTAACGCTGCCAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP045059|1|1|3002273-3002424|PILER-CR
CCGGTTTATCCCCGCTGGCGCGGGGAACAC	TAGCAATGGAAATATTTGCATGGATAGTTGC
GCGGTTTATCCCCGCTGGCGCGGGGAACAC	ATCGCCGGGGCGGGCAATGACGCCAGCTCAC
CCGGTTTATCCCCGCTGGCGCGGGGAACACCCCCCCTGATTATTTTTTATCCGTTTCAGTAACGGTTTATCCCCGCTGGCGCGGGGAACACCCGAAACCCGCTATAACGAATAACAGTGCTCACGGTTTATCCCCGCTGGCGCGGGGAACAC	TGATCAGGAGTGCCGCCGATAACAGCCAGAAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCTGGGGACATTCACCTGCATGACCTTGAGGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AACACGGCGGCAATATCGCGCCCCTGACTGGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AACACGGCGGCAATATCGCGCCCCTGACTGGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCCCGAGCTACCGCCAGGACTTATTGAAGTGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCAAACAAACTGCGGTTTTATGGCTCGCTGAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACAAACATTGCAGCTACGTTAATTGGATCAAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCAAACGGGCTCATTTTCCACTGCGCGGCCTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CTGCGCGACAACTTCATCGAACAGGTCACAGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CGCTACGCAGTCCGCGAGAATATCCTGCGCAC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TCGTCGAGGCGGATGAAATAGTGGTTAGCATC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGCGCCAGGGAACCGGTTAAACCCTGTGTTGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTTCTCAGGGGTTGGATTGTTAACGCTGCCAA


>NZ_CP045059|1|2|3002518-3003340|PILER-CR
	TAGCAATGGAAATATTTGCATGGATAGTTGC
GCGGTTTATCCCCGCTGGCGCGGGGAACAC	ATCGCCGGGGCGGGCAATGACGCCAGCTCAC
CCGGTTTATCCCCGCTGGCGCGGGGAACACCCCCCCTGATTATTTTTTATCCGTTTCAGTAACGGTTTATCCCCGCTGGCGCGGGGAACACCCGAAACCCGCTATAACGAATAACAGTGCTCACGGTTTATCCCCGCTGGCGCGGGGAACAC	TGATCAGGAGTGCCGCCGATAACAGCCAGAAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTCTGGGGACATTCACCTGCATGACCTTGAGGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AACACGGCGGCAATATCGCGCCCCTGACTGGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AACACGGCGGCAATATCGCGCCCCTGACTGGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CCCCGAGCTACCGCCAGGACTTATTGAAGTGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCAAACAAACTGCGGTTTTATGGCTCGCTGAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC	ACAAACATTGCAGCTACGTTAATTGGATCAAT
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GCAAACGGGCTCATTTTCCACTGCGCGGCCTG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CTGCGCGACAACTTCATCGAACAGGTCACAGG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CGCTACGCAGTCCGCGAGAATATCCTGCGCAC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TCGTCGAGGCGGATGAAATAGTGGTTAGCATC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AGCGCCAGGGAACCGGTTAAACCCTGTGTTGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	GTTCTCAGGGGTTGGATTGTTAACGCTGCCAA
CGGTTTATCCCCGCTGGCGCGGGGAACAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045059.1\|WP_024145756.1\|3012330_3013284_+\|SPI-1-type-III-secretion-system-effector-SopD	unknown	unknown	gnl\|CDD\|185277
NZ_CP045059.1\|WP_023198028.1\|3013371_3014106_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP045059.1\|WP_001518648.1\|3003436_3003730_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
NZ_CP045059.1\|WP_023221921.1\|2998543_2999983_-\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP045059.1\|WP_000134246.1\|2994821_2995871_-\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP045059.1\|WP_021294299.1\|2997075_2997387_-\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP045059.1\|WP_000490481.1\|3001151_3002198_+\|aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP045059.1\|WP_021294578.1\|3009223_3011887_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP045059.1\|WP_000144837.1\|3003729_3004650_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP045059.1\|WP_000741643.1\|2996346_2997057_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP045059.1\|WP_021294579.1\|3004646_3005297_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP045059.1\|WP_001173663.1\|2997951_2998557_-\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP045059.1\|WP_020437813.1\|3007107_3007656_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP045059.1\|WP_020437812.1\|3006035_3007094_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP045059.1\|WP_023222981.1\|3007652_3009212_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP045059.1\|WP_020437811.1\|3005278_3006025_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP045059.1\|WP_001221538.1\|2994079_2994841_-\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP045059.1\|WP_023197873.1\|2999992_3000901_-\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP045059.1\|WP_001118109.1\|2997577_2997934_-\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP045059.1\|WP_001219244.1\|2995867_2996347_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851

Protein	Function_ID	Function_description	E-value
NZ_CP045059.1\|WP_024145756.1\|3012330_3013284_+\|SPI-1-type-III-secretion-system-effector-SopD	gnl\|CDD\|185277	PRK15379, PRK15379, type III secretion system effector SopD.	0
NZ_CP045059.1\|WP_023198028.1\|3013371_3014106_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	8.71158e-139
NZ_CP045059.1\|WP_001518648.1\|3003436_3003730_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	1.1867e-62
NZ_CP045059.1\|WP_023221921.1\|2998543_2999983_-\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP045059.1\|WP_000134246.1\|2994821_2995871_-\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NZ_CP045059.1\|WP_021294299.1\|2997075_2997387_-\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	3.61312e-65
NZ_CP045059.1\|WP_000490481.1\|3001151_3002198_+\|aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP045059.1\|WP_021294578.1\|3009223_3011887_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
NZ_CP045059.1\|WP_000144837.1\|3003729_3004650_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	7.95508e-157
NZ_CP045059.1\|WP_000741643.1\|2996346_2997057_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	7.75163e-119
NZ_CP045059.1\|WP_021294579.1\|3004646_3005297_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	1.45049e-74
NZ_CP045059.1\|WP_001173663.1\|2997951_2998557_-\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	4.61291e-146
NZ_CP045059.1\|WP_020437813.1\|3007107_3007656_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	1.36817e-32
NZ_CP045059.1\|WP_020437812.1\|3006035_3007094_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	4.71017e-137
NZ_CP045059.1\|WP_023222981.1\|3007652_3009212_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	2.9036e-172
NZ_CP045059.1\|WP_020437811.1\|3005278_3006025_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	2.09777e-48
NZ_CP045059.1\|WP_001221538.1\|2994079_2994841_-\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.7078e-146
NZ_CP045059.1\|WP_023197873.1\|2999992_3000901_-\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP045059.1\|WP_001118109.1\|2997577_2997934_-\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	4.85353e-49
NZ_CP045059.1\|WP_001219244.1\|2995867_2996347_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.27909e-104

>NZ_CP045059.1|WP_000490481.1|3001151_3002198_+|aminopeptidase
MFSATRRFAVILALGVGFILPAQAASPGPGEIANTQARHIATFFPGRMTGSPAEMLSADYLRQQFTQMGYQSDIRTFNSRFIYTTKDNRKNWHNVTGSTVIAAHEGRVPQQIIIMAHLDTYAPQSDADVDANLGGLTLQGMDDNAAGLGVMLELAARLKDIPTHYGIRFIATSGEEEGKLGAENLLKRMSDAEKKNTLLVINLDNLIVGDKLYFNSGKNTPEAVRTLTRDRALAIARRYGIAANTNPGRNPSYPKGTGCCNDAEVFDKAGISVLSVEATNWNLGKKDGYQQRVKNASFPNGNSWHDVRLDNQQHIDKALPGRIERRSRDVVRIMLPLVKELAKAEKTS
>NZ_CP045059.1|WP_023197873.1|2999992_3000901_-|sulfate-adenylyltransferase-subunit-CysD
MDQKRLTHLWQLEAESIHIIREVAAEFANPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYAFRDRTANAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWRNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMVDDDRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESHAQTLPEIIEEMLVSTTSERQGRMIDRDQAGSMELKKRQGYF
>NZ_CP045059.1|WP_023221921.1|2998543_2999983_-|sulfate-adenylyltransferase-subunit-CysN
MNTILAQQIANEGGVEAWMMAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTLQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYREETFARIREDYLTFAEQLPGDLDIRFVPLSALEGDNVAAQSANMRWHSGPTLLEVLETVDIQRAVDRQPMRFPVQYVNRPNLDFRGYAGTLASGSVKVGERIKVLPSGVESSVARIVTFNGDKEEACAGEAITLVLNDDIDISRGDLLLAANETLAPARHAAIDVVWMAEQPLAPGQSYDVKLAGKKTRARIEAIRYQIDINNLTQRDVESLPLNGIGLVEMTFDEPLALDIYQQNPVTGGLIFIDRLSNVTVGAGMVRELDERGATPPVEYSAFELELNALVRRHFPHWDARDLLGDKHGAA
>NZ_CP045059.1|WP_001173663.1|2997951_2998557_-|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTYLLDGDNVRHGLCRDLGFSDADRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS
>NZ_CP045059.1|WP_001118109.1|2997577_2997934_-|DUF3561-family-protein
MPGMVKVTGFNMRNSHNITFTRSDAFMVDDDATSAFPGAVVGFVSWLLALGIPFLLYGPNTLFFFLYTWPFFLALMPVSVIIGIALHLLVKGKILFSIMFTLLAVGALFGALFIWLLG
>NZ_CP045059.1|WP_021294299.1|2997075_2997387_-|cell-division-protein-FtsB
MGKLTLLLLALLVWLQYSLWFGKNGIHDYSRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEAIEERARNELSMTKPGETFYRLVPDASKRAATAGQTHR
>NZ_CP045059.1|WP_000741643.1|2996346_2997057_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MAATLLDVCAVVPAAGFGRRMQTECPKQYLSIGNKTILEHSVHALLAHPRVTRVVIAISPGDHRFAQLPLANHPQISVVDGGNERADSVLAGLQAVAKAQWVLVHDAARPCLHQDDLARLLAISENSRVGGILASPVRDTMKRGEPGKNAIAHTVERADLWHALTPQFFPRELLLDCLTRALNEGATITDEASALEYCGFHPALVEGRADNIKVTRPEDLALAEFYLTRTIHQEKA
>NZ_CP045059.1|WP_001219244.1|2995867_2996347_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK
>NZ_CP045059.1|WP_000134246.1|2994821_2995871_-|tRNA-pseudouridine(13)-synthase-TruD
MTEFDNLTWLHGKPQGSGLLKANPEDFVVVEDLGFTPDGEGEHILLRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDFSAFQLEGCKVLEYARHKRKLRLGALKGNAFTLVLREISDRRDVETRLQAIRDGGVPNYFGAQRFGIGGSNLQGALRWAQSNAPVRDRNKRSFWLSAARSALFNQIVHQRLKKPDFNQVVDGDALQLAGRGSWFVATSEELPELQRRVDEKELMITASLPGSGEWGTQRAALAFEQDAIAQETVLQSLLLREKVEASRRAMLLYPQQLSWNWWDDVTVELRFWLPAGSFATSVVRELINTMGDYAHIAE
>NZ_CP045059.1|WP_001221538.1|2994079_2994841_-|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNVPDLPLAQVKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVDEGYVSVTPLHVDLTAHSAHDVVSDWLDSVGVGTQW
>NZ_CP045059.1|WP_001518648.1|3003436_3003730_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAVWLLEVRAGVYVGDTSKRIREMIWQQITQLGGVGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVENQ
>NZ_CP045059.1|WP_000144837.1|3003729_3004650_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLNPIPLKDRTSMIFLQYGQIDVLDGAFVLINKTGVRTHIPVGSVACIMLEPGTRVSHAAVHLASTVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALDDDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRATYALLAKQYGVKWHGRNYDPKDWEKGDVVNRCISAATSCLYGISEAAILAAGYAPAIGFIHSGKPLSFVYDIADIIKFESVVPKAFEIAARHPAEPDKEVRLACRDIFRSSKLTGKLIPLIEEVLAAGEIKPPQPAPDMLPPAIPEPESLGDSGHRGHG
>NZ_CP045059.1|WP_021294579.1|3004646_3005297_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTSELSPAQLLHLVERGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQEQPAASAIFDAQTRPFAPMLSAGQTLRFNLRANPTVCKNGKRHDLLMEAKRQRKTQGDSQDIWSYQQQAALTWLARQGEQNGFTLREASVDAYRQQQIRREKSRQMIQFSSVDYTGVLVINDPVLFLQRLAQGYGKSRAFGCGMMMIKPGDDA
>NZ_CP045059.1|WP_020437811.1|3005278_3006025_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLVFQLHGPMASWGVDAPGEVRHSHELPSRSALLGLLAAALGIRRDEEERLNAFNRHYQFLLCASGNPRWARDYHTVQMPKEVRKARYFSRREELQDPELLSALISRRDYYTDAWWMIAVSATPDAPYTLAQLQAALQHPVFPLYLGRKSHPLALPLAPQLLEGSAADVLREAYRQYQDKFNALKLPLPRLQNECWWEGEHDGLTANKILRRRDMPLSRQQWLFGERSVNQGPWLRKEDACISQE
>NZ_CP045059.1|WP_020437812.1|3006035_3007094_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGAKRLRISSQSLKRAWRTSELFEQALAGNIGIRTGRIAREAAQILIDSGIDAKKAVEYVEKIANCFGKVKAEKKPKDELTNAETEQLVHISPAEFEGVKALAHRLAEEKRAPQEEELALLRKDRMAVDIAMFGRMLANKPDFNVEAACQVAHAFGVSETIIEDDFFTAVDDLRQASAEDAGAGHLGETGFGSALFYTYICIDKDLLVKNLNGNEELANKTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTDQLNVAVKRITSLHKNMNKVYGQRTDTASFDVMNQQGSMKDVLDFICA
>NZ_CP045059.1|WP_020437813.1|3007107_3007656_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVQEDHKATLRKWHEDLQEKRGARASLRRSKTVNEACLSEGFHLLLMQTHSLWKNKADWHVTALAITAVLAAHIKFIDERQSFATQLGQKKSGDNPVMSKLRFSRLSAVKTPEELLRQLRRAVQLLDGSVNLISLADDIFRWCQEQDDLLSHHRRQQRPTEFLRIRWALEYYQAGDNEQD
>NZ_CP045059.1|WP_023222981.1|3007652_3009212_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MDNFSLLTTPWLPVRFKDGSTGKLAPVNLADENVVDIAATRADLQGAAWQFLLGLLQCSIAAKRYKNWEDIWFDGLHADALHKALAPLEHAFQFGAETPSFMQDFEELPDNKITIASLLPETPGIQTTELNTDHFIKRGVMECFCPHCAALALFSMQLNAPSGGQGYRTGLRGGGPLTTLIELQEYQGERQTPLWRKLWLNVMPQDAADLPLPVVYDAAVFPWLAATRTSEPPAHTITTDEQVNKLQAYWGMPRRIRLDFATIRQGVCNICGNNSDELLIQMLVKNYGVNYDRWRHPLTPHRLQIKNSKGFEPVITQPGGLLWRDWLGLSQENPTEKNTEYPAQVIKVFNARELRNIKVGLWGFGADFKKMKIRCWYEHHFPLLMTEGLIPDLRKATQTATRLLSLLRSALKEAWFANAKGARGDFSFIDIDFWNLTQGRFLNLIHDLENGHKPDERLNKWQRELWLFTRCYFDDHVFTNPYESSDLERIMKARKKYFTSSAEKQSAKAAKAKKQEAAE
>NZ_CP045059.1|WP_021294578.1|3009223_3011887_-|CRISPR-associated-helicase/endonuclease-Cas3
MSIYHYWGKSRRGETDGGDDYHLLCWHSLDVAAVGYWMVINNIYFIDHYLKKLGIQDKEQAAQFFAWILCWHDIGKFAHSFQQLYRHEALNIFNEPTRHYEKIAHTTLGYVLWNSWLSECPELFPPSSLSVRKSKRVMALWMPVTTGHHGRPPEAIQELDHFRQQDKDAARDFLLRIKALFPLITLPEAWDEDEGIDQFQQLSWFISAAVVLADWTGSASRYFPRTAEKMPVDTYWQQALAKAQTAITLFPSAANVSAFTGIETLFPFIQHPTPLQQKALELDINVDGAQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLYFGLPTMATANAMFERMANTWLALYQPDSRPSLILAHSARRLMDRFNQSIWSVTLSGTEEPDEAQPDSQGCAAWFADSNKKALLAEVGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAWMSRILEGLIERQASNGNATILLSATLSQQQRDKLVAAFSRGVRRSVQAPLLGHDDYPWLTQVTQTELISQRVDTRKEVERSVDIGWLHSEEACLERIGEAVEKGNCIAWIRNSVDDAIRIYRQLQLSKVVATENLLLFHSRFAFHDRQRIESQMLNLFGKQSGAQRAGKVIIATQVIEQSLDIDCDEMISDLAPVDLLIQRAGRLQRHIRDRNGLVKKSGQDERETPVLRILAPEWDDAPRENWLSSAMRNSAYVYPDHGRMWLTQRILREQGTIRMPQSARLLIESVYGEDVNMPVGFAKTEQLQKGKFYCDRAFARQMLLNFAPGYCAEISDSLPEKMSTRLAEESVTLWLAKIVDGVVTPYTSGEHAWEMSVLRVRQSWWNKHKDEFEKLDGEPLRKWCAQQHQDKDFATVIVVTDCAACGYSANEGLIGMMGE
>NZ_CP045059.1|WP_024145756.1|3012330_3013284_+|SPI-1-type-III-secretion-system-effector-SopD
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNIEDINKIYAFKRLQHLACPAHQDLFTIKLDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGSKMTWHPELLQESISTLRKEVTGNAQIKATVYEMMRPTEAPDHPLVEWQDSLTADEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHSYSPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT
>NZ_CP045059.1|WP_023198028.1|3013371_3014106_-|phosphoadenosine-phosphosulfate-reductase
MSQLDLNALNELPKVDRVLALAETNAQLEKLSAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNEINKVEPMNRALKELNAQTWFAGLRREQSGSRAHLPVLATQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG

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Crispr_ID: NZ_CP045059_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP045059_2

3019476-3019627

TypeI-E

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACACA	CRISPRCasFinder

2 spacers

cas3,cas8e,cse2gr11,cas7

The CRISPR arrays of NZ_CP045059_2

>merge|NZ_CP045059|2|3019476-3019627|CRISPRCasFinder
ACGGCTATCCTTGTTGGCGCGGGGAACACGGCTACACGCAAAAATTCCAGTCGTTGGCGCACGGTTTATCCCCGCTGGCGCGGGGAACACAAAGGGAGCCAAATCTGCCGCATGACCATCGTCGGTTTATCCCCGCTGGCGCGGGGAACACA

>NZ_CP045059|2|2|3019476-3019627|CRISPRCasFinder
ACGGCTATCCTTGTTGGCGCGGGGAACACG	GCTACACGCAAAAATTCCAGTCGTTGGCGCA
CGGTTTATCCCCGCTGGCGCGGGGAACACA	AAGGGAGCCAAATCTGCCGCATGACCATCGT
CGGTTTATCCCCGCTGGCGCGGGGAACACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045059.1\|WP_023198028.1\|3013371_3014106_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP045059.1\|WP_024145756.1\|3012330_3013284_+\|SPI-1-type-III-secretion-system-effector-SopD	unknown	unknown	gnl\|CDD\|185277
NZ_CP045059.1\|WP_021294578.1\|3009223_3011887_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP045059.1\|WP_000832395.1\|3030076_3030547_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185179
NZ_CP045059.1\|WP_000210451.1\|3023975_3024776_-\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP045059.1\|WP_023198026.1\|3015893_3017693_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
NZ_CP045059.1\|WP_020437812.1\|3006035_3007094_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP045059.1\|WP_001199961.1\|3019922_3020594_-\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP045059.1\|WP_023198027.1\|3014181_3015894_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
NZ_CP045059.1\|WP_001540810.1\|3018580_3019378_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|224158
NZ_CP045059.1\|WP_000036734.1\|3020729_3022028_-\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP045059.1\|WP_000108313.1\|3018128_3018491_+\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
NZ_CP045059.1\|WP_001079646.1\|3030543_3031080_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185168
NZ_CP045059.1\|WP_000178267.1\|3029555_3030062_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185178
NZ_CP045059.1\|WP_020437813.1\|3007107_3007656_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP045059.1\|WP_077908752.1\|3026050_3028750_+\|fimbrial-biogenesis-outer-membrane-usher-protein	unknown	unknown	gnl\|CDD\|185176
NZ_CP045059.1\|WP_000210863.1\|3022110_3023748_-\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP045059.1\|WP_023222981.1\|3007652_3009212_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP045059.1\|WP_000842512.1\|3025383_3025971_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185169
NZ_CP045059.1\|WP_023222979.1\|3028762_3029536_+\|fimbria/pilus-periplasmic-chaperone	unknown	unknown	gnl\|CDD\|185177

Protein	Function_ID	Function_description	E-value
NZ_CP045059.1\|WP_023198028.1\|3013371_3014106_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	8.71158e-139
NZ_CP045059.1\|WP_024145756.1\|3012330_3013284_+\|SPI-1-type-III-secretion-system-effector-SopD	gnl\|CDD\|185277	PRK15379, PRK15379, type III secretion system effector SopD.	0
NZ_CP045059.1\|WP_021294578.1\|3009223_3011887_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	0
NZ_CP045059.1\|WP_000832395.1\|3030076_3030547_+\|fimbrial-protein	gnl\|CDD\|185179	PRK15276, PRK15276, putative fimbrial subunit SteE; Provisional.	1.31755e-98
NZ_CP045059.1\|WP_000210451.1\|3023975_3024776_-\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	3.42454e-158
NZ_CP045059.1\|WP_023198026.1\|3015893_3017693_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
NZ_CP045059.1\|WP_020437812.1\|3006035_3007094_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	4.71017e-137
NZ_CP045059.1\|WP_001199961.1\|3019922_3020594_-\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	1.43874e-155
NZ_CP045059.1\|WP_023198027.1\|3014181_3015894_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
NZ_CP045059.1\|WP_001540810.1\|3018580_3019378_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|224158	COG1237, COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only].	1.65501e-102
NZ_CP045059.1\|WP_000036734.1\|3020729_3022028_-\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP045059.1\|WP_000108313.1\|3018128_3018491_+\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	2.78454e-58
NZ_CP045059.1\|WP_001079646.1\|3030543_3031080_+\|fimbrial-protein	gnl\|CDD\|185168	PRK15260, PRK15260, fimbrial protein SteF; Provisional.	7.785e-121
NZ_CP045059.1\|WP_000178267.1\|3029555_3030062_+\|fimbrial-protein	gnl\|CDD\|185178	PRK15275, PRK15275, putative fimbrial protein SteD; Provisional.	7.03659e-105
NZ_CP045059.1\|WP_020437813.1\|3007107_3007656_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	1.36817e-32
NZ_CP045059.1\|WP_077908752.1\|3026050_3028750_+\|fimbrial-biogenesis-outer-membrane-usher-protein	gnl\|CDD\|185176	PRK15273, PRK15273, fimbrial biogenesis outer membrane usher protein.	0
NZ_CP045059.1\|WP_000210863.1\|3022110_3023748_-\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP045059.1\|WP_023222981.1\|3007652_3009212_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	2.9036e-172
NZ_CP045059.1\|WP_000842512.1\|3025383_3025971_+\|fimbrial-protein	gnl\|CDD\|185169	PRK15261, PRK15261, fimbrial protein SteA; Provisional.	5.36845e-100
NZ_CP045059.1\|WP_023222979.1\|3028762_3029536_+\|fimbria/pilus-periplasmic-chaperone	gnl\|CDD\|185177	PRK15274, PRK15274, putative periplasmic fimbrial chaperone protein SteC; Provisional.	0

>NZ_CP045059.1|WP_001540810.1|3018580_3019378_-|MBL-fold-metallo-hydrolase
MALRIRVLLENHKGAGADKSLKARPGLSLLVEDESTSILFDTGPDGSFMQNALAMGIDLSDVSAVVLSHGHYDHCGGVPWLPDNSRIICHPDIARERYAAMTFLGITRKIKKLSCEVDYSRYRMMYTRDPLPIGENFIWSGEIPVVAPEAYGIFGGHDAEPDSILDEGVLIYQSTKGLVIITGCGHRGIANIVRHCQNITGIKRIYALVGGFHLRCASPFTLWRVRRFLQEHKPEKLCGCHCTGAWGRLWLPEITAPATGDVLRF
>NZ_CP045059.1|WP_000108313.1|3018128_3018491_+|6-carboxytetrahydropterin-synthase-QueD
MSTTLYKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIMDFADLKAAFKPTYDRLDHYYLNDIPGLSNPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCVYRGE
>NZ_CP045059.1|WP_023198026.1|3015893_3017693_-|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTPAPLTGLLPLNPEQLARLQAATTDLTPEQLAWVSGYFWGVLNPRSGAVAVTPAPEGKMSGITLISASQTGNARRVAEALRDDLLAANLNVTLVNAGDYKFKQIASEKLLVIVTSTQGEGEPPEEAVALHKFLFSKKAPKLTDTAFAVFGLGDTSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDVLKSRAPVAAPSQSVATGSVNDIHTSPYTKDAPLAATLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVDGKTLPLAEALEWHFELTVNTANIVENYATLTRSESLLPLVGDKAQLQHYAATTPIVDMVRFSPAQLDAQALIGLLRPLTPRLYSIASAQAEVESEVHITVGVVRYDIEGRARAGGASSFFADRVEEEGEVRVFIEHNDNFRLPANPQTPVIMIGPGTGIAPFRSFMQQRAAEGVEGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLSRIDLAWSRDQKEKIYVQDKLREQGAELWRWINDGAHIYVCGDARRMAADVEKALLEVIAEFGGMDLESADEYLSELRVERRYQRDVY
>NZ_CP045059.1|WP_023198027.1|3014181_3015894_-|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLSDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAAQKLEPRHAMLLRCRLPGGVITTTQWQAIDKFAADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGATYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVDTFKEEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDKWHLTLFIENGRILDYPGRPLKTGLLEIAKIHQGEFRITANQNLIIASVPESQKAKIEKLARDHGLMNAVSAQRENSMACVSFPTCPLAMAEAERFLPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGNRIGTRIPRMYQENITEPDILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDFWE
>NZ_CP045059.1|WP_023198028.1|3013371_3014106_-|phosphoadenosine-phosphosulfate-reductase
MSQLDLNALNELPKVDRVLALAETNAQLEKLSAEERVAWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNEINKVEPMNRALKELNAQTWFAGLRREQSGSRAHLPVLATQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>NZ_CP045059.1|WP_024145756.1|3012330_3013284_+|SPI-1-type-III-secretion-system-effector-SopD
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNIEDINKIYAFKRLQHLACPAHQDLFTIKLDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGSKMTWHPELLQESISTLRKEVTGNAQIKATVYEMMRPTEAPDHPLVEWQDSLTADEKSMLACINAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHSYSPFAEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT
>NZ_CP045059.1|WP_021294578.1|3009223_3011887_-|CRISPR-associated-helicase/endonuclease-Cas3
MSIYHYWGKSRRGETDGGDDYHLLCWHSLDVAAVGYWMVINNIYFIDHYLKKLGIQDKEQAAQFFAWILCWHDIGKFAHSFQQLYRHEALNIFNEPTRHYEKIAHTTLGYVLWNSWLSECPELFPPSSLSVRKSKRVMALWMPVTTGHHGRPPEAIQELDHFRQQDKDAARDFLLRIKALFPLITLPEAWDEDEGIDQFQQLSWFISAAVVLADWTGSASRYFPRTAEKMPVDTYWQQALAKAQTAITLFPSAANVSAFTGIETLFPFIQHPTPLQQKALELDINVDGAQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLYFGLPTMATANAMFERMANTWLALYQPDSRPSLILAHSARRLMDRFNQSIWSVTLSGTEEPDEAQPDSQGCAAWFADSNKKALLAEVGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAWMSRILEGLIERQASNGNATILLSATLSQQQRDKLVAAFSRGVRRSVQAPLLGHDDYPWLTQVTQTELISQRVDTRKEVERSVDIGWLHSEEACLERIGEAVEKGNCIAWIRNSVDDAIRIYRQLQLSKVVATENLLLFHSRFAFHDRQRIESQMLNLFGKQSGAQRAGKVIIATQVIEQSLDIDCDEMISDLAPVDLLIQRAGRLQRHIRDRNGLVKKSGQDERETPVLRILAPEWDDAPRENWLSSAMRNSAYVYPDHGRMWLTQRILREQGTIRMPQSARLLIESVYGEDVNMPVGFAKTEQLQKGKFYCDRAFARQMLLNFAPGYCAEISDSLPEKMSTRLAEESVTLWLAKIVDGVVTPYTSGEHAWEMSVLRVRQSWWNKHKDEFEKLDGEPLRKWCAQQHQDKDFATVIVVTDCAACGYSANEGLIGMMGE
>NZ_CP045059.1|WP_023222981.1|3007652_3009212_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MDNFSLLTTPWLPVRFKDGSTGKLAPVNLADENVVDIAATRADLQGAAWQFLLGLLQCSIAAKRYKNWEDIWFDGLHADALHKALAPLEHAFQFGAETPSFMQDFEELPDNKITIASLLPETPGIQTTELNTDHFIKRGVMECFCPHCAALALFSMQLNAPSGGQGYRTGLRGGGPLTTLIELQEYQGERQTPLWRKLWLNVMPQDAADLPLPVVYDAAVFPWLAATRTSEPPAHTITTDEQVNKLQAYWGMPRRIRLDFATIRQGVCNICGNNSDELLIQMLVKNYGVNYDRWRHPLTPHRLQIKNSKGFEPVITQPGGLLWRDWLGLSQENPTEKNTEYPAQVIKVFNARELRNIKVGLWGFGADFKKMKIRCWYEHHFPLLMTEGLIPDLRKATQTATRLLSLLRSALKEAWFANAKGARGDFSFIDIDFWNLTQGRFLNLIHDLENGHKPDERLNKWQRELWLFTRCYFDDHVFTNPYESSDLERIMKARKKYFTSSAEKQSAKAAKAKKQEAAE
>NZ_CP045059.1|WP_020437813.1|3007107_3007656_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVQEDHKATLRKWHEDLQEKRGARASLRRSKTVNEACLSEGFHLLLMQTHSLWKNKADWHVTALAITAVLAAHIKFIDERQSFATQLGQKKSGDNPVMSKLRFSRLSAVKTPEELLRQLRRAVQLLDGSVNLISLADDIFRWCQEQDDLLSHHRRQQRPTEFLRIRWALEYYQAGDNEQD
>NZ_CP045059.1|WP_020437812.1|3006035_3007094_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGAKRLRISSQSLKRAWRTSELFEQALAGNIGIRTGRIAREAAQILIDSGIDAKKAVEYVEKIANCFGKVKAEKKPKDELTNAETEQLVHISPAEFEGVKALAHRLAEEKRAPQEEELALLRKDRMAVDIAMFGRMLANKPDFNVEAACQVAHAFGVSETIIEDDFFTAVDDLRQASAEDAGAGHLGETGFGSALFYTYICIDKDLLVKNLNGNEELANKTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTDQLNVAVKRITSLHKNMNKVYGQRTDTASFDVMNQQGSMKDVLDFICA
>NZ_CP045059.1|WP_001199961.1|3019922_3020594_-|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWDKLSDREVSLFSILAKTKESDKWGAASSEDLLAVINRQGYTARHVVITGGEPCIHDLMPLTDLLEKSGFSCQIETSGTHEVRCTPNTWVTVSPKVNMRGGYDVLSQALERANEIKHPVGRVRDIEALDELLATLSDDKPRVIALQPISQKEDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP045059.1|WP_000036734.1|3020729_3022028_-|phosphopyruvate-hydratase
MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVGAVNGPIAQAILGKDAKDQAGIDKIMIDLDGTENKSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKGKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP045059.1|WP_000210863.1|3022110_3023748_-|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQLAVDIGREHALFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISMKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARNVAGMDNANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLSDDSLVRQLYGASTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAANEHQKRQAK
>NZ_CP045059.1|WP_000210451.1|3023975_3024776_-|nucleoside-triphosphate-pyrophosphohydrolase
MTTNHQIDRLLTLMQRLRDPENGCPWDKEQTFASIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFGELSADNSEEALVRWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCSNVGFDWTTLGPVVDKVYEEIDEVMFEARQAVVDQAKLEEEMGDLLFATVNMARHLGTKAELALQKANDKFERRFREVERIVAARGLEMTGVDLETMEEVWQEVKRQEIDL
>NZ_CP045059.1|WP_000842512.1|3025383_3025971_+|fimbrial-protein
MKSSHFCKLAVTASLVMGIVSGAQAAGSNTAKVTFLGNIVDSPCSVTLDTEDQTVNMGSSIGNGTLSNGKTTINNARTFHIDLEGCTWATEKNMNVVFTTGSGTTAATGATDNLALMKTDGTGAISNVSLAIGDAGKNNIKLGDTYTQAIADLDGDTILDEKQSLNFTAWLVGAATGTVGTGEFSSAANVTISYL
>NZ_CP045059.1|WP_077908752.1|3026050_3028750_+|fimbrial-biogenesis-outer-membrane-usher-protein
MMNNTWKSVLCPIACGVGMLLSVSPYSASGKDIEFNTDFLDVKNRDNVNIAQFSRKGFILPGVYLLQIKINGQTLPQEFPVNWVIPEHDPQGSEVCAEPELVTQLGIKPELAEKLVWITHGERQCLAPDSLKGMDFQADLGHSTLLVNLPQAYMEYSDVDWDPPARWDNGIPGIILDYNINNQLRHDQESGSEEQSISGNGTLGANLGAWRLRADWQASYDHRDDDENTSTLHDQSWSRYYAYRALPTLGAKLTLGESYLQSDVFDSFNYIGASVISDDQMLPPKLRGYAPEIVGIARSNAKVKVSWQGRVLYETQVPAGPFRIQDLNQSVSGTLHVTVEEQNGQTQEFDVNTASVPFLTRPGMVRYKMALGRPQDWDHHPITGTFASAEASWGVTNGWSLYGGAIGESNYQAVALGSGKDLGVVGAVAVDITHSIAHMPQDDGFDGETLQGNSYRISYSRDFDEIDSRLTFAGYRFSEKNFMSMSDYLDAKTYHHLNAGHEKERYTVTYNQNFREQGMSAYFSYSRSTFWDSPDQSNYNLSLSWYFDLGSIKNLSASLNGYRSEYNGDKDDGVYISLSVPWGNDSISYNGTFNGSQHRNQLGYSGHSQNGDNWQLHVGQDEQGAQADGYYSHQGALTDIDLSADYEEGSYRSLGMSLRGGMTLTTQGGALHRGSLAGSTRLLVDTDGIADVPVSGNGSPTSTNIFGKAVIADVGSYSRSLARIDLNKLPEKAEATKSVVQITLTEGAIGYRHFDVVSGEKMMAVFRLADGDFPPFGAEVKNERQQQLGLVADDGNAWLAGVKAGETLKVFWDGAAQCEASLPPTFTPELLANALLLPCKILEGQPPTAPQKSSPLPAQPLIQEHTQTDGQPAAPVATTTQTPPIPLADNHAVNRKDME
>NZ_CP045059.1|WP_023222979.1|3028762_3029536_+|fimbria/pilus-periplasmic-chaperone
MNKTNHFKRQALIASVLLAAPLVSHSAIVPDRTRVIFNGNENSITVTLKNGNATLPYLAQAWLEDDKLAKDTRYFTALPPLQRIEPKSDGQVKVQPLPAAASLPQDRESLFYFNVREIPPKSDKPNTLQLALQTRIKFFYRPVAVARQVDKTHPWQTKLTLTYQGDGVIFDNPTPFYLVISNAGSKENETASGFKNLLIAPREKVTSPIKGASLGSSPVVGYVDDYGGHRLLVFTCSGNTCKVNEEKTRDAEKKANK
>NZ_CP045059.1|WP_000178267.1|3029555_3030062_+|fimbrial-protein
MTMLTRWKMLVLLCGGFVAGTEAAGTKTVQLELHLVVTQPPPCTVGGASVEFGDVLTTKVGDASQTKPVGYSLNCDGRASDYLKLQIQGTTTTISGEQVLQTSVQGLGIRIQQAGNKQLVPVGITDWLNFTLSGSNGPELEAVPVKEPTTQLAGGDFNASATLVVDYQ
>NZ_CP045059.1|WP_000832395.1|3030076_3030547_+|fimbrial-protein
MKRVLILTLLITQFACADNLTFHGKLINPPACTINNGETLEVSFGSVIIDNIDGVNYLTEIPWTLTCDSSFRDDALTFTLSYLGTATPYSAKALTTSVPELGIELQQNGTVFPPGTSLTINESSLPTLKAVPVKQPGKEPAEGDFEAFATLQVDYQ
>NZ_CP045059.1|WP_001079646.1|3030543_3031080_+|fimbrial-protein
MNRIFQTAGHLIGGVMLWAVCNTLPAATPNVHYSGKLVAGACNLVVDNDTMATVDFHTIGSDNFDASGQTTPVPFTLSLQDCKTALANGVLVTFQGVEDSTLPGLLALEPSSEASGFAIGVETAAQQPVSINATVGTAFVLKEGITTINLQARLQKYAGEEVMPGEFSGSATVSFEYQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP045059_2	2.2\|3019567\|31\|NZ_CP045059\|CRISPRCasFinder	3019567-3019597	31	NZ_CP045059.1	715249-715279	1	0.968

1. spacer 2.2|3019567|31|NZ_CP045059|CRISPRCasFinder matches to position: 715249-715279, mismatch: 1, identity: 0.968

aagggagccaaatctgccgcatgaccatcgt	CRISPR spacer
aagggagccaaatctgccgcatgaccgtcgt	Protospacer
**************************.****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP045059_1	1.14\|3003036\|32\|NZ_CP045059\|CRISPRCasFinder,CRT,PILER-CR	3003036-3003067	32	NZ_CP044178	Salmonella enterica subsp. enterica serovar Concord strain AR-0407 plasmid pAR-0407-1	30628-30659	2	0.938
NZ_CP045059_1	1.1\|3002242\|32\|NZ_CP045059\|CRISPRCasFinder,CRT	3002242-3002273	32	NC_006824	Aromatoleum aromaticum EbN1 plasmid 2, complete sequence	25444-25475	6	0.812
NZ_CP045059_1	1.14\|3003036\|32\|NZ_CP045059\|CRISPRCasFinder,CRT,PILER-CR	3003036-3003067	32	MH632120	Mycobacterium phage Thonko, complete genome	6035-6066	6	0.812
NZ_CP045059_1	1.3\|3002364\|32\|NZ_CP045059\|CRISPRCasFinder,CRT	3002364-3002395	32	NC_013860	Azospirillum sp. B510 plasmid pAB510f, complete sequence	12149-12180	7	0.781
NZ_CP045059_1	1.14\|3003036\|32\|NZ_CP045059\|CRISPRCasFinder,CRT,PILER-CR	3003036-3003067	32	LT599585	Pseudomonas veronii 1YdBTEX2 genome assembly, plasmid: PVE_plasmid	94726-94757	7	0.781
NZ_CP045059_1	1.20\|3002364\|31\|NZ_CP045059\|PILER-CR	3002364-3002394	31	NC_015583	Novosphingobium sp. PP1Y plasmid Mpl, complete sequence	1026941-1026971	7	0.774
NZ_CP045059_1	1.20\|3002364\|31\|NZ_CP045059\|PILER-CR	3002364-3002394	31	CP042595	Streptomyces albogriseolus strain LBX-2 plasmid pSALBX2, complete sequence	12524-12554	7	0.774
NZ_CP045059_1	1.3\|3002364\|32\|NZ_CP045059\|CRISPRCasFinder,CRT	3002364-3002395	32	NC_015583	Novosphingobium sp. PP1Y plasmid Mpl, complete sequence	1026941-1026972	8	0.75
NZ_CP045059_1	1.3\|3002364\|32\|NZ_CP045059\|CRISPRCasFinder,CRT	3002364-3002395	32	CP042595	Streptomyces albogriseolus strain LBX-2 plasmid pSALBX2, complete sequence	12523-12554	8	0.75
NZ_CP045059_1	1.14\|3003036\|32\|NZ_CP045059\|CRISPRCasFinder,CRT,PILER-CR	3003036-3003067	32	NZ_CP039896	Rhizobium pusense strain CFBP5875 plasmid pAtCFBP5875, complete sequence	40576-40607	8	0.75
NZ_CP045059_1	1.14\|3003036\|32\|NZ_CP045059\|CRISPRCasFinder,CRT,PILER-CR	3003036-3003067	32	NZ_CP039918	Agrobacterium tumefaciens strain CFBP6626 plasmid pAtCFBP6626a, complete sequence	71482-71513	8	0.75
NZ_CP045059_1	1.14\|3003036\|32\|NZ_CP045059\|CRISPRCasFinder,CRT,PILER-CR	3003036-3003067	32	NZ_CP039913	Agrobacterium tumefaciens strain CFBP6625 plasmid pAtCFBP6625b, complete sequence	133525-133556	8	0.75
NZ_CP045059_1	1.14\|3003036\|32\|NZ_CP045059\|CRISPRCasFinder,CRT,PILER-CR	3003036-3003067	32	NZ_CP039909	Agrobacterium tumefaciens strain CFBP6624 plasmid pAtCFBP6624, complete sequence	259824-259855	8	0.75
NZ_CP045059_1	1.3\|3002364\|32\|NZ_CP045059\|CRISPRCasFinder,CRT	3002364-3002395	32	NZ_CP020911	Rhizobium etli strain NXC12 plasmid pRetNXC12e, complete sequence	153622-153653	9	0.719
NZ_CP045059_1	1.14\|3003036\|32\|NZ_CP045059\|CRISPRCasFinder,CRT,PILER-CR	3003036-3003067	32	NZ_CP010801	Ralstonia mannitolilytica strain SN82F48 plasmid pRMAN01, complete sequence	134672-134703	9	0.719
NZ_CP045059_1	1.16\|3003158\|32\|NZ_CP045059\|CRISPRCasFinder,CRT,PILER-CR	3003158-3003189	32	AP018698	Arthrobacter sp. MN05-02 plasmid plasmid1 DNA, complete genome	127276-127307	9	0.719
NZ_CP045059_1	1.20\|3002364\|31\|NZ_CP045059\|PILER-CR	3002364-3002394	31	NZ_CP020911	Rhizobium etli strain NXC12 plasmid pRetNXC12e, complete sequence	153622-153652	9	0.71
NZ_CP045059_1	1.20\|3002364\|31\|NZ_CP045059\|PILER-CR	3002364-3002394	31	NC_013860	Azospirillum sp. B510 plasmid pAB510f, complete sequence	12149-12179	9	0.71
NZ_CP045059_1	1.4\|3002425\|32\|NZ_CP045059\|CRISPRCasFinder,CRT	3002425-3002456	32	NZ_CP011404	Lactobacillus salivarius str. Ren plasmid pR1, complete sequence	14283-14314	10	0.688
NZ_CP045059_1	1.4\|3002425\|32\|NZ_CP045059\|CRISPRCasFinder,CRT	3002425-3002456	32	NZ_CP017108	Lactobacillus salivarius strain CICC23174 plasmid pLS_1 sequence	170262-170293	10	0.688
NZ_CP045059_1	1.8\|3002670\|32\|NZ_CP045059\|CRISPRCasFinder,CRT,PILER-CR	3002670-3002701	32	MT889371	Microbacterium phage DelaGarza, complete genome	20155-20186	10	0.688
NZ_CP045059_1	1.9\|3002731\|32\|NZ_CP045059\|CRISPRCasFinder,CRT,PILER-CR	3002731-3002762	32	MT889371	Microbacterium phage DelaGarza, complete genome	20155-20186	10	0.688
NZ_CP045059_1	1.13\|3002975\|32\|NZ_CP045059\|CRISPRCasFinder,CRT,PILER-CR	3002975-3003006	32	NZ_CP050104	Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b2, complete sequence	304278-304309	10	0.688
NZ_CP045059_1	1.13\|3002975\|32\|NZ_CP045059\|CRISPRCasFinder,CRT,PILER-CR	3002975-3003006	32	NZ_CP025507	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvA, complete sequence	7051-7082	10	0.688
NZ_CP045059_1	1.13\|3002975\|32\|NZ_CP045059\|CRISPRCasFinder,CRT,PILER-CR	3002975-3003006	32	NZ_CP050109	Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b2, complete sequence	304278-304309	10	0.688
NZ_CP045059_1	1.13\|3002975\|32\|NZ_CP045059\|CRISPRCasFinder,CRT,PILER-CR	3002975-3003006	32	NZ_CP030761	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed1, complete sequence	279065-279096	10	0.688
NZ_CP045059_1	1.13\|3002975\|32\|NZ_CP045059\|CRISPRCasFinder,CRT,PILER-CR	3002975-3003006	32	NZ_CP022666	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence	721171-721202	10	0.688
NZ_CP045059_1	1.13\|3002975\|32\|NZ_CP045059\|CRISPRCasFinder,CRT,PILER-CR	3002975-3003006	32	NZ_CP050086	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence	318301-318332	10	0.688

1. spacer 1.14|3003036|32|NZ_CP045059|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP044178 (Salmonella enterica subsp. enterica serovar Concord strain AR-0407 plasmid pAR-0407-1) position: , mismatch: 2, identity: 0.938

ctgcgcgacaacttcatcgaacaggtcacagg	CRISPR spacer
ctgcgcgacaacttcatcgaacagggcgcagg	Protospacer
************************* *.****

2. spacer 1.1|3002242|32|NZ_CP045059|CRISPRCasFinder,CRT matches to NC_006824 (Aromatoleum aromaticum EbN1 plasmid 2, complete sequence) position: , mismatch: 6, identity: 0.812

gatttttcgccagccactccagccagt--gctgc	CRISPR spacer
gcttcttcgccagccactcccgccattcggct--	Protospacer
* **.*************** **** *  ***

3. spacer 1.14|3003036|32|NZ_CP045059|CRISPRCasFinder,CRT,PILER-CR matches to MH632120 (Mycobacterium phage Thonko, complete genome) position: , mismatch: 6, identity: 0.812

ctgcgcgacaacttcatcgaacaggtcacagg-	CRISPR spacer
cagcgcgacgacttcatcgagcagg-cacgcga	Protospacer
* *******.**********.**** ***. *

4. spacer 1.3|3002364|32|NZ_CP045059|CRISPRCasFinder,CRT matches to NC_013860 (Azospirillum sp. B510 plasmid pAB510f, complete sequence) position: , mismatch: 7, identity: 0.781

atcgccggggcgggcaatgacgccagctcacc--	CRISPR spacer
ggcggcggggcgggcaatgacacca--tcagcgg	Protospacer
. ** ****************.***  *** *

5. spacer 1.14|3003036|32|NZ_CP045059|CRISPRCasFinder,CRT,PILER-CR matches to LT599585 (Pseudomonas veronii 1YdBTEX2 genome assembly, plasmid: PVE_plasmid) position: , mismatch: 7, identity: 0.781

ctgcgcgacaacttcatcgaacag-gtcacagg	CRISPR spacer
ctgcgcgacaagttcttcgaacagcattgcaa-	Protospacer
*********** *** ******** .*..**.

6. spacer 1.20|3002364|31|NZ_CP045059|PILER-CR matches to NC_015583 (Novosphingobium sp. PP1Y plasmid Mpl, complete sequence) position: , mismatch: 7, identity: 0.774

atcgccggggcgggcaatgacgccagctcac	CRISPR spacer
atcgccggcgcgggcaatgaagccgggcgat	Protospacer
******** *********** ***.* . *.

7. spacer 1.20|3002364|31|NZ_CP045059|PILER-CR matches to CP042595 (Streptomyces albogriseolus strain LBX-2 plasmid pSALBX2, complete sequence) position: , mismatch: 7, identity: 0.774

atcgccggggcgggcaatgacgccagctcac	CRISPR spacer
ctcgccgggccgggcaaggacgccgaccctc	Protospacer
 ******** ******* ******..*.* *

8. spacer 1.3|3002364|32|NZ_CP045059|CRISPRCasFinder,CRT matches to NC_015583 (Novosphingobium sp. PP1Y plasmid Mpl, complete sequence) position: , mismatch: 8, identity: 0.75

atcgccggggcgggcaatgacgccagctcacc	CRISPR spacer
atcgccggcgcgggcaatgaagccgggcgata	Protospacer
******** *********** ***.* . *.

9. spacer 1.3|3002364|32|NZ_CP045059|CRISPRCasFinder,CRT matches to CP042595 (Streptomyces albogriseolus strain LBX-2 plasmid pSALBX2, complete sequence) position: , mismatch: 8, identity: 0.75

atcgccggggcgggcaatgacgccagctcacc	CRISPR spacer
ctcgccgggccgggcaaggacgccgaccctct	Protospacer
 ******** ******* ******..*.* *.

10. spacer 1.14|3003036|32|NZ_CP045059|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039896 (Rhizobium pusense strain CFBP5875 plasmid pAtCFBP5875, complete sequence) position: , mismatch: 8, identity: 0.75

ctgcgcgacaacttcatcgaacaggtcacagg	CRISPR spacer
atcctcgacaacttcctcgagcaggtcatata	Protospacer
 * * ********** ****.*******.* .

11. spacer 1.14|3003036|32|NZ_CP045059|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039918 (Agrobacterium tumefaciens strain CFBP6626 plasmid pAtCFBP6626a, complete sequence) position: , mismatch: 8, identity: 0.75

ctgcgcgacaacttcatcgaacaggtcacagg	CRISPR spacer
atcctcgacaacttcctcgagcaggtcatata	Protospacer
 * * ********** ****.*******.* .

12. spacer 1.14|3003036|32|NZ_CP045059|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039913 (Agrobacterium tumefaciens strain CFBP6625 plasmid pAtCFBP6625b, complete sequence) position: , mismatch: 8, identity: 0.75

ctgcgcgacaacttcatcgaacaggtcacagg	CRISPR spacer
atcctcgacaacttcctcgagcaggtcatata	Protospacer
 * * ********** ****.*******.* .

13. spacer 1.14|3003036|32|NZ_CP045059|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039909 (Agrobacterium tumefaciens strain CFBP6624 plasmid pAtCFBP6624, complete sequence) position: , mismatch: 8, identity: 0.75

ctgcgcgacaacttcatcgaacaggtcacagg	CRISPR spacer
atcctcgacaacttcctcgagcaggtcatata	Protospacer
 * * ********** ****.*******.* .

14. spacer 1.3|3002364|32|NZ_CP045059|CRISPRCasFinder,CRT matches to NZ_CP020911 (Rhizobium etli strain NXC12 plasmid pRetNXC12e, complete sequence) position: , mismatch: 9, identity: 0.719

atcgccggggcgggcaatgacgccagctcacc	CRISPR spacer
tccggcggggccggcaatgacgccatgtggac	Protospacer
 .** ****** *************  * . *

15. spacer 1.14|3003036|32|NZ_CP045059|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP010801 (Ralstonia mannitolilytica strain SN82F48 plasmid pRMAN01, complete sequence) position: , mismatch: 9, identity: 0.719

ctgcgcgacaacttcatcgaacaggtcacagg	CRISPR spacer
gtaggcggcaacttcatcgatcaggtcgatcg	Protospacer
 *. ***.************ ******.   *

16. spacer 1.16|3003158|32|NZ_CP045059|CRISPRCasFinder,CRT,PILER-CR matches to AP018698 (Arthrobacter sp. MN05-02 plasmid plasmid1 DNA, complete genome) position: , mismatch: 9, identity: 0.719

tcgtcgagg-----cggatgaaatagtggttagcatc	CRISPR spacer
-----gaaagaatccggatgaaatagtggttggcctc	Protospacer
     **..     *****************.** **

17. spacer 1.20|3002364|31|NZ_CP045059|PILER-CR matches to NZ_CP020911 (Rhizobium etli strain NXC12 plasmid pRetNXC12e, complete sequence) position: , mismatch: 9, identity: 0.71

atcgccggggcgggcaatgacgccagctcac	CRISPR spacer
tccggcggggccggcaatgacgccatgtgga	Protospacer
 .** ****** *************  * .

18. spacer 1.20|3002364|31|NZ_CP045059|PILER-CR matches to NC_013860 (Azospirillum sp. B510 plasmid pAB510f, complete sequence) position: , mismatch: 9, identity: 0.71

atcgccggggcgggcaatgacgccagctcac	CRISPR spacer
ggcggcggggcgggcaatgacaccatcagcg	Protospacer
. ** ****************.*** *

19. spacer 1.4|3002425|32|NZ_CP045059|CRISPRCasFinder,CRT matches to NZ_CP011404 (Lactobacillus salivarius str. Ren plasmid pR1, complete sequence) position: , mismatch: 10, identity: 0.688

cccccctgattattttttatccgtttcagtaa	CRISPR spacer
aaaggatgaatattttttatcagtttcagata	Protospacer
      *** *********** *******  *

20. spacer 1.4|3002425|32|NZ_CP045059|CRISPRCasFinder,CRT matches to NZ_CP017108 (Lactobacillus salivarius strain CICC23174 plasmid pLS_1 sequence) position: , mismatch: 10, identity: 0.688

cccccctgattattttttatccgtttcagtaa	CRISPR spacer
aaaggatgaatattttttatcagtttcagata	Protospacer
      *** *********** *******  *

21. spacer 1.8|3002670|32|NZ_CP045059|CRISPRCasFinder,CRT,PILER-CR matches to MT889371 (Microbacterium phage DelaGarza, complete genome) position: , mismatch: 10, identity: 0.688

aacacggcggcaatatcgcgcccctgactggg	CRISPR spacer
tggagggcggcaatctcacgcccctgaccctc	Protospacer
 . * ********* **.**********.

22. spacer 1.9|3002731|32|NZ_CP045059|CRISPRCasFinder,CRT,PILER-CR matches to MT889371 (Microbacterium phage DelaGarza, complete genome) position: , mismatch: 10, identity: 0.688

aacacggcggcaatatcgcgcccctgactggg	CRISPR spacer
tggagggcggcaatctcacgcccctgaccctc	Protospacer
 . * ********* **.**********.

23. spacer 1.13|3002975|32|NZ_CP045059|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP050104 (Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b2, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaacgggctcattttccactgcgcggcctg	CRISPR spacer
tctttgatgctcaatttccactgcgcggtctt	Protospacer
 *    . ***** **************.**

24. spacer 1.13|3002975|32|NZ_CP045059|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP025507 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvA, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaacgggctcattttccactgcgcggcctg	CRISPR spacer
tcttcgatgctcaatttccactgcgcggtctt	Protospacer
 *    . ***** **************.**

25. spacer 1.13|3002975|32|NZ_CP045059|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP050109 (Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b2, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaacgggctcattttccactgcgcggcctg	CRISPR spacer
tctttgatgctcaatttccactgcgcggtctt	Protospacer
 *    . ***** **************.**

26. spacer 1.13|3002975|32|NZ_CP045059|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP030761 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaacgggctcattttccactgcgcggcctg	CRISPR spacer
tcttcgatgctcaatttccactgcgcggtctt	Protospacer
 *    . ***** **************.**

27. spacer 1.13|3002975|32|NZ_CP045059|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022666 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaacgggctcattttccactgcgcggcctg	CRISPR spacer
tcttcgatgctcaatttccactgcgcggtctt	Protospacer
 *    . ***** **************.**

28. spacer 1.13|3002975|32|NZ_CP045059|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP050086 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence) position: , mismatch: 10, identity: 0.688

gcaaacgggctcattttccactgcgcggcctg	CRISPR spacer
tcttcgatgctcaatttccactgcgcggtctt	Protospacer
 *    . ***** **************.**

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

968248 : 975561

Dickeya_phage(16.67%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001201759.1\|968248_969367_+	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	8.1e-09	39.8
WP_001748306.1\|969363_971310_+	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	9.1e-40	42.3
WP_000447499.1\|971439_971661_-	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	9.3e-18	64.2
WP_000520787.1\|971984_972305_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	3.5e-13	45.7
WP_000934064.1\|972335_974612_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	6.2e-165	42.3
WP_001117984.1\|974824_975022_-	hypothetical protein	NA	NA	NA	NA
WP_001531374.1\|975183_975561_-	hypothetical protein	A0A077KET4	Ralstonia_phage	1.7e-19	40.2

DBSCAN-SWA_2

1076969 : 1123441

Salmonella_phage(25.0%)

head,protease,integrase,tail,lysis

attL 1072090:1072105|attR 1103838:1103853

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1072090:1072105	attL	NA	NA	NA	NA
WP_000374046.1\|1076969_1077629_-\|protease	FtsH protease modulator YccA	A0A2H4JFM9	uncultured_Caudovirales_phage	2.7e-44	52.4
WP_097361317.1\|1078216_1079239_-\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	3.5e-91	51.9
WP_024134793.1\|1079222_1079459_-	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_097361318.1\|1079538_1079955_-	hypothetical protein	NA	NA	NA	NA
WP_058645056.1\|1080048_1080312_-	DUF4222 domain-containing protein	NA	NA	NA	NA
WP_097361319.1\|1080314_1080707_-	hypothetical protein	A0A0M4RTV1	Salmonella_phage	6.6e-06	42.4
WP_057395058.1\|1080703_1080973_-	hypothetical protein	NA	NA	NA	NA
WP_153789541.1\|1080969_1081161_-	hypothetical protein	NA	NA	NA	NA
WP_097361321.1\|1081157_1081373_-	hypothetical protein	NA	NA	NA	NA
WP_097361322.1\|1081372_1081660_-	hypothetical protein	I6RSM9	Salmonella_phage	5.1e-24	94.7
WP_097361323.1\|1081656_1081971_-	hypothetical protein	A0A222YY67	Escherichia_phage	2.0e-34	57.3
WP_097361324.1\|1082006_1082822_-	hypothetical protein	A0A2H4JAZ0	uncultured_Caudovirales_phage	1.9e-87	64.7
WP_097361325.1\|1082827_1085422_-	exonuclease VIII	V5UQJ3	Shigella_phage	9.6e-162	56.3
WP_097361326.1\|1085562_1085895_-	hypothetical protein	NA	NA	NA	NA
WP_024153606.1\|1085970_1086177_-	cell division inhibitor protein	I6PBM9	Cronobacter_phage	3.0e-10	45.6
WP_097361327.1\|1086180_1086456_-	hypothetical protein	NA	NA	NA	NA
WP_097361328.1\|1086481_1087333_-	transcriptional regulator	A0A0P0ZE80	Stx2-converting_phage	5.5e-58	57.4
WP_058679873.1\|1087641_1087884_+	hypothetical protein	NA	NA	NA	NA
WP_079816621.1\|1087944_1088214_-	hypothetical protein	NA	NA	NA	NA
WP_097361329.1\|1088585_1089080_-	helix-turn-helix domain-containing protein	A0A0R6PH50	Moraxella_phage	7.5e-15	58.8
WP_024153610.1\|1089151_1089427_+	hypothetical protein	H6WRX5	Salmonella_phage	1.3e-08	39.2
WP_097361330.1\|1089423_1089918_+	hypothetical protein	NA	NA	NA	NA
WP_097361331.1\|1089965_1090973_+	DUF1376 domain-containing protein	A0A0U2RT81	Escherichia_phage	1.0e-127	69.6
WP_097361332.1\|1090965_1091427_+	replication protein	A0A0U2JGJ0	Escherichia_phage	3.2e-68	76.2
WP_097361333.1\|1091442_1091838_+	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	1.5e-18	37.4
WP_097361334.1\|1091834_1092107_+	hypothetical protein	NA	NA	NA	NA
WP_023220363.1\|1092231_1092444_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	1.8e-18	77.1
WP_097361335.1\|1092910_1093510_+	DUF1367 family protein	A0A0U2RT94	Escherichia_phage	1.5e-97	82.9
WP_097361336.1\|1093506_1093701_+	hypothetical protein	S4TNP0	Salmonella_phage	7.9e-13	61.5
WP_097361337.1\|1093697_1093979_+	DUF1364 family protein	K7P7Q1	Enterobacteria_phage	1.7e-35	79.1
WP_097361338.1\|1093975_1094512_+	DUF1133 family protein	A0A0U2S606	Escherichia_phage	1.1e-64	66.3
WP_097361339.1\|1095042_1096473_+	hypothetical protein	NA	NA	NA	NA
WP_001525456.1\|1096657_1096960_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_097361340.1\|1096937_1097477_+	lysozyme	K7PLY1	Enterobacteria_phage	2.4e-75	69.5
WP_097361563.1\|1097794_1098250_+\|lysis	lysis protein	A0A0M4RD57	Salmonella_phage	1.9e-57	81.9
WP_070799731.1\|1098475_1098664_+	DUF826 domain-containing protein	NA	NA	NA	NA
WP_079828278.1\|1098727_1099357_+	hypothetical protein	A0A0M3ULJ9	Salmonella_phage	3.3e-108	98.1
WP_079953322.1\|1099359_1100979_+	TerL protein	A0A0M5M1R6	Salmonella_phage	1.7e-262	80.1
WP_097361341.1\|1100978_1102487_+	DUF1073 domain-containing protein	A0A2R3UAL5	Myoviridae_environmental_samples	1.4e-104	42.7
WP_097361342.1\|1102527_1103217_+\|head	phage head morphogenesis protein	H9C0V1	Aeromonas_phage	1.8e-59	50.9
WP_097361343.1\|1103213_1104569_+	DUF2213 domain-containing protein	A0A219YCD3	Aeromonas_phage	9.4e-68	37.8
1103838:1103853	attR	NA	NA	NA	NA
WP_097361344.1\|1104570_1105053_+	hypothetical protein	A0A1X9SFC3	Acinetobacter_phage	1.4e-26	49.4
WP_079953317.1\|1105052_1106081_+	DUF2184 domain-containing protein	A0A219YBB0	Aeromonas_phage	1.7e-82	49.1
WP_097361345.1\|1106084_1106432_+	hypothetical protein	A0A1X9SFA9	Acinetobacter_phage	3.1e-07	33.3
WP_079953315.1\|1106437_1106884_+	DUF4054 domain-containing protein	H9C0W0	Aeromonas_phage	1.4e-15	43.8
WP_097361346.1\|1106877_1107462_+	hypothetical protein	H9C0W2	Aeromonas_phage	1.7e-13	27.9
WP_097361347.1\|1107458_1107824_+	hypothetical protein	A0A077KAW7	Edwardsiella_phage	5.1e-21	40.5
WP_097361348.1\|1107808_1108354_+	hypothetical protein	NA	NA	NA	NA
WP_097361349.1\|1108334_1109819_+	DUF3383 domain-containing protein	A0A077KGV4	Edwardsiella_phage	3.4e-95	40.2
WP_000016414.1\|1109819_1110266_+	hypothetical protein	Q2NPD1	Xanthomonas_phage	4.8e-21	40.4
WP_000101348.1\|1110265_1110670_+	hypothetical protein	H9C0W7	Aeromonas_phage	1.8e-19	44.8
WP_000228831.1\|1110711_1110894_+	hypothetical protein	NA	NA	NA	NA
WP_000741779.1\|1110877_1113049_+	transglycosylase SLT domain-containing protein	A0A0M4REK7	Salmonella_phage	1.4e-49	67.1
WP_097361350.1\|1113045_1113756_+	hypothetical protein	A0A077KGW3	Edwardsiella_phage	2.5e-27	34.6
WP_000890115.1\|1113755_1114058_+	hypothetical protein	A0A077K9U4	Edwardsiella_phage	7.0e-24	49.5
WP_000122818.1\|1114054_1114924_+	hypothetical protein	A0A077KC17	Edwardsiella_phage	9.1e-32	32.7
WP_000068499.1\|1114904_1115582_+	oxidoreductase	A0A077KAY0	Edwardsiella_phage	5.4e-32	36.4
WP_001191865.1\|1115594_1115951_+	hypothetical protein	A0A077KCA1	Edwardsiella_phage	1.6e-19	49.1
WP_001293657.1\|1115947_1117189_+	hypothetical protein	A0A077KGW9	Edwardsiella_phage	1.2e-101	49.9
WP_097361351.1\|1117190_1117793_+	DUF2612 domain-containing protein	A0A2R3UAM9	Myoviridae_environmental_samples	4.3e-33	38.9
WP_097361352.1\|1117782_1119234_+\|tail	tail fiber protein	E5G6P0	Salmonella_phage	1.7e-46	72.8
WP_097361353.1\|1119734_1120040_+	hypothetical protein	A0A0M4QWS3	Salmonella_phage	1.9e-29	60.0
WP_097361354.1\|1120029_1120764_+	DUF4376 domain-containing protein	A0A0M4RTP2	Salmonella_phage	1.7e-47	76.1
WP_097361355.1\|1120818_1122936_+	sialate O-acetylesterase	H6WZJ9	Escherichia_phage	2.4e-163	53.7
WP_057395107.1\|1123066_1123441_+	DUF1353 domain-containing protein	I1TQ41	Pseudomonas_phage	1.5e-15	41.3

DBSCAN-SWA_3

1817349 : 1911741

103

Enterobacteria_phage(44.74%)

head,protease,terminase,integrase,capsid,transposase,portal,tail,lysis,tRNA

attL 1809439:1809454|attR 1907733:1907748

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1809439:1809454	attL	NA	NA	NA	NA
WP_000173208.1\|1817349_1818606_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_000174484.1\|1818919_1819543_+	lipoprotein localization protein LolB	NA	NA	NA	NA
WP_000988258.1\|1819539_1820391_+	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase	NA	NA	NA	NA
WP_001518537.1\|1820656_1821604_+	ribose-phosphate pyrophosphokinase	A0A2K9L2G2	Tupanvirus	8.6e-44	37.8
WP_001037188.1\|1821728_1823414_+	C4-dicarboxylic acid transporter DauA	A0A2H4J153	uncultured_Caudovirales_phage	2.3e-23	23.4
WP_000823878.1\|1823458_1823737_-	stress-induced protein YchH	NA	NA	NA	NA
WP_000365078.1\|1823987_1824596_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_001748456.1\|1824712_1825804_+	redox-regulated ATPase YchF	NA	NA	NA	NA
WP_001748457.1\|1825962_1827228_-	DUF4427 domain-containing protein	NA	NA	NA	NA
WP_001058311.1\|1827727_1828846_+	hydrogenase 1 small subunit	NA	NA	NA	NA
WP_000070986.1\|1828842_1830636_+	Ni/Fe-hydrogenase large subunit	NA	NA	NA	NA
WP_020438146.1\|1830654_1831386_+	Ni/Fe-hydrogenase b-type cytochrome subunit	NA	NA	NA	NA
WP_000993801.1\|1831382_1831979_+\|protease	hydrogenase 1 maturation protease	NA	NA	NA	NA
WP_001615886.1\|1831968_1832373_+	hydrogenase-1 operon protein HyaE	NA	NA	NA	NA
WP_000063377.1\|1832369_1833218_+	hydrogenase expression/formation protein	NA	NA	NA	NA
WP_000263613.1\|1833292_1834837_+	cytochrome bd-II oxidase subunit 1	NA	NA	NA	NA
WP_000888110.1\|1834848_1835985_+	cytochrome d ubiquinol oxidase subunit II	NA	NA	NA	NA
WP_000270306.1\|1835997_1836087_+	cytochrome bd-II oxidase subunit CbdX	NA	NA	NA	NA
WP_001526439.1\|1836481_1837756_+	Glu/Leu/Phe/Val dehydrogenase	NA	NA	NA	NA
WP_020438149.1\|1837969_1839682_+	alpha,alpha-trehalase	NA	NA	NA	NA
WP_000511323.1\|1839744_1839999_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_020438150.1\|1840167_1840902_+	flagellar brake protein YcgR	NA	NA	NA	NA
WP_000776974.1\|1840915_1841527_-	membrane-bound lytic murein transglycosylase EmtA	NA	NA	NA	NA
WP_020438151.1\|1841696_1842611_+	muramoyltetrapeptide carboxypeptidase	NA	NA	NA	NA
WP_000338376.1\|1842707_1844441_+	potassium/proton antiporter	NA	NA	NA	NA
WP_023197862.1\|1844502_1845573_-	catabolic alanine racemase DadX	NA	NA	NA	NA
WP_001266937.1\|1845586_1846885_-	D-amino acid dehydrogenase	NA	NA	NA	NA
WP_000190831.1\|1847207_1848740_+	SpoVR family protein	NA	NA	NA	NA
WP_000234826.1\|1848786_1849506_-	fatty acid metabolism transcriptional regulator FadR	NA	NA	NA	NA
WP_000406446.1\|1849725_1851270_+	Na(+)/H(+) antiporter NhaB	NA	NA	NA	NA
WP_000943475.1\|1851411_1851942_+	disulfide bond formation protein DsbB	NA	NA	NA	NA
WP_079952872.1\|1852177_1852315_-	Hok/Gef family protein	NA	NA	NA	NA
WP_079952870.1\|1852874_1853255_-	DUF1353 domain-containing protein	I1TQ41	Pseudomonas_phage	5.2e-16	41.6
WP_153789548.1\|1853385_1854672_-	hypothetical protein	S5MDQ7	Escherichia_phage	2.1e-56	38.3
WP_097361386.1\|1855751_1856375_-	DUF4376 domain-containing protein	Q9LA61	Enterobacterial_phage	2.2e-32	37.8
WP_097361387.1\|1856386_1857583_-	hypothetical protein	H6WZM9	Escherichia_phage	8.4e-20	50.5
WP_057393620.1\|1857724_1857877_-	Hok/Gef family protein	NA	NA	NA	NA
WP_097361388.1\|1861697_1862402_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	2.0e-66	61.2
WP_097361389.1\|1862299_1863037_-\|tail	phage tail protein	A0A0P0ZE89	Stx2-converting_phage	1.4e-113	75.2
WP_097361390.1\|1863046_1863742_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	1.1e-91	69.3
WP_097361391.1\|1863896_1865060_-	porin OmpC	Q1MVN1	Enterobacteria_phage	5.3e-112	55.6
WP_079953114.1\|1865197_1865530_-\|tail	phage tail protein	A0A0K2FIE9	Enterobacteria_phage	7.0e-33	61.1
WP_097361392.1\|1865526_1868622_-\|tail	phage tail tape measure protein	A0A291AWX1	Escherichia_phage	1.9e-241	51.8
WP_079953116.1\|1868605_1868908_-\|tail	phage tail assembly protein T	A5LH37	Enterobacteria_phage	7.5e-26	59.4
WP_057395189.1\|1868928_1869318_-\|tail	phage minor tail protein G	A5LH36	Enterobacteria_phage	6.5e-30	57.0
WP_057395195.1\|1869374_1870127_-\|tail	phage tail protein	A5LH35	Enterobacteria_phage	1.0e-95	70.4
WP_001643846.1\|1870139_1870541_-\|tail	phage tail protein	A0A291AWY2	Escherichia_phage	9.6e-45	60.6
WP_057395188.1\|1870540_1871140_-\|tail	phage tail protein	A0A291AWZ0	Escherichia_phage	9.9e-70	69.7
WP_097361393.1\|1871156_1871513_-\|tail	phage tail protein	K7P6U9	Enterobacteria_phage	1.7e-32	58.5
WP_057395186.1\|1871523_1871898_-	DNA breaking-rejoining protein	NA	NA	NA	NA
WP_057395185.1\|1871962_1872991_-\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	1.9e-108	58.1
WP_057395184.1\|1873084_1873432_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	2.1e-19	53.8
WP_057395183.1\|1873428_1874952_-	S49 family peptidase	A0A0K2FI53	Enterobacteria_phage	4.5e-103	53.7
WP_097361394.1\|1874941_1876537_-\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	2.6e-186	61.4
WP_057395181.1\|1876533_1876737_-\|tail	phage tail protein	K7PM10	Enterobacteria_phage	1.3e-18	80.0
WP_079953120.1\|1876720_1878655_-\|terminase	phage terminase large subunit family protein	E4WL19	Enterobacteria_phage	2.9e-256	65.8
WP_057395179.1\|1878626_1879172_-\|terminase	terminase small subunit	K7P7G0	Enterobacteria_phage	7.6e-53	61.3
WP_097361395.1\|1879632_1880829_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_070809067.1\|1881009_1881300_+	lipoprotein bor	C6ZCX3	Enterobacteria_phage	8.2e-30	62.9
WP_097361565.1\|1881331_1881766_-\|lysis	lysis protein	A0A0M4RD57	Salmonella_phage	4.1e-49	73.9
WP_153789549.1\|1881918_1882086_-	hypothetical protein	NA	NA	NA	NA
WP_079953123.1\|1882403_1882889_-	lysozyme	M9P0E5	Enterobacteria_phage	1.1e-58	69.4
WP_097361566.1\|1882869_1883157_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_079953022.1\|1883333_1883561_+	hypothetical protein	Q38575	Escherichia_phage	2.4e-08	42.5
WP_097361396.1\|1883550_1883931_-	hypothetical protein	NA	NA	NA	NA
WP_079953024.1\|1884606_1885089_-	cell envelope integrity protein TolA	NA	NA	NA	NA
WP_079953025.1\|1885308_1885563_+	type II toxin-antitoxin system HicA family toxin	R4JMD3	Burkholderia_phage	5.0e-15	42.9
WP_079953026.1\|1885559_1885901_+	type II toxin-antitoxin system HicB family antitoxin	NA	NA	NA	NA
WP_079953027.1\|1886043_1886793_-	hypothetical protein	NA	NA	NA	NA
WP_097361397.1\|1886693_1887830_-	DUF968 domain-containing protein	A0A1W6JP62	Morganella_phage	4.6e-52	33.9
WP_097361398.1\|1887851_1888220_-	hypothetical protein	NA	NA	NA	NA
WP_097361399.1\|1888291_1890244_-	replication endonuclease	F1BUS0	Erwinia_phage	7.6e-95	33.4
WP_097361400.1\|1890322_1890550_-	derepression protein	NA	NA	NA	NA
WP_057394489.1\|1891043_1891307_-	DUF4222 domain-containing protein	NA	NA	NA	NA
WP_097361402.1\|1891309_1891732_-	hypothetical protein	Q9G078	Enterobacteria_phage	3.8e-28	56.6
WP_097361403.1\|1891735_1892209_-	class I SAM-dependent methyltransferase	H9C170	Pectobacterium_phage	5.2e-66	77.5
WP_058645051.1\|1893269_1893518_-	hypothetical protein	NA	NA	NA	NA
WP_079953034.1\|1893514_1893910_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	2.7e-15	36.9
WP_097361404.1\|1893906_1896225_-	hypothetical protein	A0A0U2I1R6	Escherichia_phage	1.6e-38	27.1
WP_153789550.1\|1896182_1896425_-	hypothetical protein	NA	NA	NA	NA
WP_097361405.1\|1896714_1896972_-	hypothetical protein	NA	NA	NA	NA
WP_057395050.1\|1897358_1897550_-	hypothetical protein	NA	NA	NA	NA
WP_057395049.1\|1897546_1897741_-	hypothetical protein	NA	NA	NA	NA
WP_097361406.1\|1897894_1898473_-	hypothetical protein	NA	NA	NA	NA
WP_057395047.1\|1898990_1899458_+	hypothetical protein	NA	NA	NA	NA
WP_125468762.1\|1899542_1899821_+	hypothetical protein	NA	NA	NA	NA
WP_097361407.1\|1899777_1900200_-	hypothetical protein	NA	NA	NA	NA
WP_079953039.1\|1900227_1900728_-	hypothetical protein	NA	NA	NA	NA
WP_097361408.1\|1900840_1901182_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_058645046.1\|1901252_1902242_+\|integrase	tyrosine-type recombinase/integrase	A0A0F7LBR0	Escherichia_phage	1.7e-98	54.0
WP_000018967.1\|1902433_1902775_+	DUF1971 domain-containing protein	NA	NA	NA	NA
WP_001083582.1\|1902846_1903020_-	addiction module toxin, GnsA/GnsB family	NA	NA	NA	NA
WP_001519337.1\|1903211_1903349_-	hypothetical protein	NA	NA	NA	NA
WP_000785716.1\|1903700_1904162_-	YcgN family cysteine cluster protein	NA	NA	NA	NA
WP_001519895.1\|1904239_1904899_-	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_001525604.1\|1904948_1905242_-	hypothetical protein	NA	NA	NA	NA
WP_000072527.1\|1905367_1906075_+	septum site-determining protein MinC	NA	NA	NA	NA
WP_000101047.1\|1906098_1906911_+	septum site-determining protein MinD	NA	NA	NA	NA
WP_001185666.1\|1906914_1907181_+	cell division topological specificity factor MinE	NA	NA	NA	NA
WP_097361409.1\|1907302_1908430_-	ribonuclease D	NA	NA	NA	NA
1907733:1907748	attR	NA	NA	NA	NA
WP_000758418.1\|1908502_1910188_-	long-chain-fatty-acid--CoA ligase FadD	A0A2H4PQM9	Staphylococcus_phage	3.8e-34	26.0
WP_021294445.1\|1910392_1910974_-	Slp family lipoprotein	NA	NA	NA	NA
WP_001221014.1\|1911045_1911741_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA

DBSCAN-SWA_4

1965843 : 1971233

uncultured_Caudovirales_phage(33.33%)

integrase

attL 1965890:1965904|attR 1976778:1976792

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_097361410.1\|1965843_1966377_-	DUF2514 domain-containing protein	A0A291LBG9	Klebsiella_phage	2.4e-11	50.0
1965890:1965904	attL	NA	NA	NA	NA
WP_001013467.1\|1966430_1966661_-	hypothetical protein	Q8HA86	Salmonella_phage	6.1e-28	93.7
WP_020438171.1\|1966691_1967798_+	hypothetical protein	Q9QF34	Lambdoid_phage	1.1e-53	65.0
WP_071602162.1\|1967794_1967989_+	hypothetical protein	A0A2H4IYC8	uncultured_Caudovirales_phage	5.9e-08	59.5
WP_072205508.1\|1968017_1968872_+\|integrase	tyrosine-type recombinase/integrase	A0A2H4IYC8	uncultured_Caudovirales_phage	1.2e-71	50.0
WP_000722368.1\|1969244_1969598_-	YebY family protein	NA	NA	NA	NA
WP_000979705.1\|1969614_1970490_-	copper homeostasis membrane protein CopD	NA	NA	NA	NA
WP_000168393.1\|1970490_1970865_-	CopC domain-containing protein YobA	NA	NA	NA	NA
WP_000856224.1\|1971002_1971233_+	DNA polymerase III subunit theta	H9C187	Pectobacterium_phage	2.9e-14	60.3
1976778:1976792	attR	NA	NA	NA	NA

DBSCAN-SWA_5

2073906 : 2085317

Morganella_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001157315.1\|2073906_2075337_-	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	1.0e-104	57.4
WP_001748531.1\|2075410_2076106_-	phosphohydrolase	A0A1D6Y7U0	Golden_Marseillevirus	2.8e-07	27.1
WP_000107434.1\|2076185_2076497_-	hypothetical protein	NA	NA	NA	NA
WP_017465542.1\|2077148_2078360_+	porin	Q1MVN1	Enterobacteria_phage	4.4e-109	56.2
WP_024131109.1\|2078619_2078808_-	hypothetical protein	NA	NA	NA	NA
WP_000208509.1\|2078818_2079031_-	cold-shock protein	A0A1W6JNX5	Morganella_phage	3.9e-21	70.0
WP_000457663.1\|2079485_2080754_-	Y-family DNA polymerase	I6RSM4	Salmonella_phage	9.3e-227	91.9
WP_000394197.1\|2080756_2081176_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	8.5e-36	60.5
WP_001537372.1\|2081302_2081464_-	hypothetical protein	NA	NA	NA	NA
WP_000598921.1\|2081944_2082742_+	DgsA anti-repressor MtfA	NA	NA	NA	NA
WP_001683376.1\|2083113_2083404_+	DUF4102 domain-containing protein	B7SYF8	Stenotrophomonas_phage	2.1e-09	52.6
WP_153789552.1\|2084048_2085317_+	DUF4102 domain-containing protein	A0A0U1UNT3	Pseudomonas_phage	4.2e-62	36.5

DBSCAN-SWA_6

2209258 : 2219765

Enterobacteria_phage(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000126351.1\|2209258_2210572_-	lipopolysaccharide biosynthesis protein RfbH	H8ZJ36	Ostreococcus_tauri_virus	9.1e-52	35.1
WP_000565902.1\|2210598_2211678_-	CDP-glucose 4,6-dehydratase	A0A222YY99	Synechococcus_phage	1.3e-16	24.5
WP_000648783.1\|2211682_2212456_-	glucose-1-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_020437413.1\|2212471_2213446_-	CDP-6-deoxy-delta-3,4-glucoseen reductase	NA	NA	NA	NA
WP_000973714.1\|2213451_2214003_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	1.0e-52	58.0
WP_000857530.1\|2214003_2214882_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	5.1e-107	64.8
WP_001023659.1\|2214929_2215829_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	5.1e-30	36.0
WP_000697840.1\|2215828_2216914_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.2e-102	53.9
WP_000981471.1\|2217290_2218184_-	GalU regulator GalF	A0A127AW70	Bacillus_phage	4.8e-44	42.2
WP_001111837.1\|2218361_2219765_-	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	3.1e-21	26.5

DBSCAN-SWA_7

2298220 : 2307391

Enterobacteria_phage(66.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021294257.1\|2298220_2300254_+\|tRNA	methionine--tRNA ligase	A0A1V0SDF2	Indivirus	1.0e-54	27.6
WP_000703137.1\|2300494_2300953_+	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	8.4e-53	72.5
WP_001197951.1\|2301124_2301655_+	YehR family lipoprotein	NA	NA	NA	NA
WP_000950413.1\|2301711_2302179_-	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	3.9e-74	90.3
WP_000598637.1\|2302225_2302945_-	two-component system response regulator BtsR	NA	NA	NA	NA
WP_000272850.1\|2302941_2304627_-	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	4.8e-279	91.3
WP_001240418.1\|2304849_2305581_+	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	4.5e-101	87.9
WP_001261696.1\|2305640_2305748_+	protein YohO	NA	NA	NA	NA
WP_000824855.1\|2305728_2306460_-	ABC transporter permease	NA	NA	NA	NA
WP_000569166.1\|2306443_2307391_-	ABC transporter ATP-binding protein	F2Y1V5	Organic_Lake_phycodnavirus	3.7e-10	27.8

DBSCAN-SWA_8

3441782 : 3481387

Pseudomonas_phage(24.24%)

head,integrase,terminase,transposase,tail,plate

attL 3441529:3441544|attR 3481496:3481511

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3441529:3441544	attL	NA	NA	NA	NA
WP_153789573.1\|3441782_3442364_-	helix-turn-helix domain-containing protein	A0A1C6ZDG7	Pseudomonas_phage	2.0e-06	34.0
WP_153789574.1\|3442530_3442797_+	transcriptional regulator	NA	NA	NA	NA
WP_153789575.1\|3442806_3444870_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A2D1GNK9	Pseudomonas_phage	1.4e-144	42.1
WP_153789576.1\|3444887_3445781_+	AAA family ATPase	A0A2D1GNS0	Pseudomonas_phage	5.6e-85	54.9
WP_153789577.1\|3445794_3446067_+	hypothetical protein	A0A0F6WDF2	Pseudomonas_phage	3.5e-06	39.0
WP_153789578.1\|3446079_3446361_+	hypothetical protein	NA	NA	NA	NA
WP_153789579.1\|3446375_3446597_+	hypothetical protein	NA	NA	NA	NA
WP_153789580.1\|3446608_3446824_+	hypothetical protein	NA	NA	NA	NA
WP_153789581.1\|3446838_3447045_+	hypothetical protein	NA	NA	NA	NA
WP_153789582.1\|3447034_3447727_+	DUF3164 family protein	Q6QIE4	Burkholderia_phage	3.0e-62	55.3
WP_153789583.1\|3447653_3447956_+	ANR family transcriptional regulator	NA	NA	NA	NA
WP_153789584.1\|3448210_3448477_+	hypothetical protein	NA	NA	NA	NA
WP_153789585.1\|3448477_3448696_+	hypothetical protein	NA	NA	NA	NA
WP_153789586.1\|3448677_3449379_+	DUF4406 domain-containing protein	A0A0K1LK36	Vibrio_phage	1.7e-17	53.7
WP_153789587.1\|3449569_3449905_+	hypothetical protein	A0A219YC07	Aeromonas_phage	4.7e-05	37.7
WP_153789588.1\|3450009_3450558_+	AsnC family protein	NA	NA	NA	NA
WP_153789589.1\|3450583_3450961_+	hypothetical protein	A0A0F6TJR3	Escherichia_coli_O157_typing_phage	2.4e-13	45.4
WP_153789590.1\|3450957_3451371_+	DUF1018 domain-containing protein	A0A2D1GNN4	Pseudomonas_phage	5.1e-33	53.6
WP_153789591.1\|3451492_3451960_+	mor transcription activator family protein	A0A2D1GNW5	Pseudomonas_phage	5.0e-21	45.0
WP_153789592.1\|3451998_3452307_+	hypothetical protein	NA	NA	NA	NA
WP_153789593.1\|3452412_3452625_+	hypothetical protein	NA	NA	NA	NA
WP_153789594.1\|3452627_3453155_+	glycoside hydrolase family protein	A0A0M3LPQ1	Mannheimia_phage	1.8e-38	46.8
WP_153789595.1\|3453139_3453718_+	hypothetical protein	K7P6W1	Enterobacteria_phage	1.1e-09	31.3
WP_153789596.1\|3453695_3453941_+	hypothetical protein	NA	NA	NA	NA
WP_153789597.1\|3453940_3454441_+	DUF1804 family protein	I6PBD1	Pseudomonas_phage	1.8e-37	50.0
WP_153789598.1\|3454427_3454643_+	hypothetical protein	NA	NA	NA	NA
WP_153789599.1\|3455160_3455628_-	hypothetical protein	NA	NA	NA	NA
WP_153789600.1\|3455642_3455816_-	hypothetical protein	NA	NA	NA	NA
WP_153789601.1\|3455934_3457578_+\|terminase	phage terminase large subunit	B7SDN0	Haemophilus_phage	4.2e-187	61.7
WP_153789602.1\|3457587_3459177_+	DUF935 family protein	H1ZZE2	Pseudomonas_virus	6.2e-111	42.9
WP_153789603.1\|3459166_3460327_+\|head	phage head morphogenesis protein	Q6QIB9	Burkholderia_phage	8.1e-52	41.5
WP_153789604.1\|3460307_3460859_+	phage virion morphogenesis protein	A0A2K9VH22	Faecalibacterium_phage	1.3e-12	32.2
WP_153789605.1\|3461076_3462240_+	hypothetical protein	A0A2D1GNS3	Pseudomonas_phage	6.2e-60	40.0
WP_153789606.1\|3462239_3462638_+	hypothetical protein	NA	NA	NA	NA
WP_153789607.1\|3462647_3463559_+\|head	head protein	A0A2H4J778	uncultured_Caudovirales_phage	2.0e-98	57.6
WP_153789608.1\|3463555_3464005_+	hypothetical protein	NA	NA	NA	NA
WP_153789609.1\|3464014_3464440_+	DUF1320 domain-containing protein	A0A1X9SGZ3	Bradyrhizobium_phage	2.8e-10	36.1
WP_153789610.1\|3464436_3465129_+	DUF1834 family protein	NA	NA	NA	NA
WP_153789611.1\|3465088_3465265_+	DUF2635 domain-containing protein	NA	NA	NA	NA
WP_153789612.1\|3465257_3466667_+\|tail	phage tail protein	A0A0M3LQC3	Mannheimia_phage	1.6e-94	43.8
WP_153789613.1\|3466675_3467050_+\|tail	phage tail protein	A0A0M3LRV6	Mannheimia_phage	7.9e-25	51.7
WP_153789614.1\|3467046_3467433_+	hypothetical protein	NA	NA	NA	NA
WP_153789615.1\|3467587_3469894_+\|tail	tail length tape measure protein	A0A0M3LPB6	Mannheimia_phage	7.2e-68	34.0
WP_153789616.1\|3469890_3471291_+	multidrug DMT transporter permease	A0A0M3LQ21	Mannheimia_phage	1.4e-29	26.3
WP_153789641.1\|3471280_3472468_+\|tail	phage tail protein	A0A2H4J9E6	uncultured_Caudovirales_phage	9.4e-72	37.1
WP_153789617.1\|3472464_3473163_+\|plate	phage baseplate assembly protein V	A0A0M3LPA3	Mannheimia_phage	5.7e-45	44.2
WP_153789618.1\|3473235_3473586_+	hypothetical protein	A0A2H4JDR8	uncultured_Caudovirales_phage	1.8e-26	55.7
WP_153789619.1\|3473585_3474644_+\|tail	phage tail protein	A0A0M3LQN4	Mannheimia_phage	1.8e-74	45.6
WP_153789620.1\|3474643_3475216_+	DUF2313 domain-containing protein	A0A0M3LQE1	Mannheimia_phage	1.2e-29	39.2
WP_153789621.1\|3476407_3477097_-	DUF4376 domain-containing protein	S5MBX6	Escherichia_phage	7.1e-64	53.1
WP_153789622.1\|3477195_3477705_-	hypothetical protein	Q37842	Escherichia_phage	1.2e-28	40.2
WP_153789623.1\|3477838_3478399_+	helix-turn-helix domain-containing protein	A0A0A7NPV4	Enterobacteria_phage	5.8e-72	77.0
WP_153789624.1\|3478472_3478649_+	hypothetical protein	NA	NA	NA	NA
WP_153789625.1\|3478693_3478957_+	XRE family transcriptional regulator	NA	NA	NA	NA
WP_153789642.1\|3479341_3481387_+	sialate O-acetylesterase	G9L6J1	Escherichia_phage	4.0e-163	51.7
3481496:3481511	attR	NA	NA	NA	NA

DBSCAN-SWA_9

4292993 : 4388471

110

Salmonella_phage(77.78%)

holin,head,protease,integrase,terminase,plate,capsid,portal,tail,tRNA

attL 4325892:4325936|attR 4358563:4358607

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001621365.1\|4292993_4293431_+\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_001518251.1\|4293475_4294417_+	fatty acid biosynthesis protein FabY	NA	NA	NA	NA
WP_001259012.1\|4294431_4294878_-	type II toxin-antitoxin system HigA family antitoxin	NA	NA	NA	NA
WP_000558166.1\|4294874_4295186_-	type II toxin-antitoxin system HigB family toxin	NA	NA	NA	NA
WP_021294279.1\|4295271_4296201_-	alpha/beta hydrolase	A0A2K9L5W3	Tupanvirus	1.3e-07	44.4
WP_001159630.1\|4296418_4296730_+	cytotoxic translational repressor of toxin-antitoxin stability system	NA	NA	NA	NA
WP_000362050.1\|4296730_4297021_+	DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_000027730.1\|4297067_4297997_-	formate dehydrogenase accessory protein FdhE	NA	NA	NA	NA
WP_000829025.1\|4297993_4298629_-	formate dehydrogenase cytochrome b556 subunit	NA	NA	NA	NA
WP_000331361.1\|4298625_4299528_-	formate dehydrogenase subunit beta	NA	NA	NA	NA
WP_077248424.1\|4299540_4302591_-	formate dehydrogenase-N subunit alpha	A0A077SK27	Escherichia_phage	4.6e-06	24.1
WP_001059740.1\|4302785_4303622_+	formate dehydrogenase accessory sulfurtransferase FdhD	NA	NA	NA	NA
WP_000710966.1\|4303889_4304921_-	YiiG family protein	NA	NA	NA	NA
WP_000828039.1\|4305103_4306204_+	DUF3829 domain-containing protein	NA	NA	NA	NA
WP_000527677.1\|4306547_4306871_-	AzlD domain-containing protein	NA	NA	NA	NA
WP_000683586.1\|4306870_4307530_-	AzlC family ABC transporter permease	NA	NA	NA	NA
WP_010989088.1\|4307612_4308179_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000619475.1\|4308267_4308582_-	L-rhamnose mutarotase	NA	NA	NA	NA
WP_097361574.1\|4308578_4309727_-	lactaldehyde reductase	NA	NA	NA	NA
WP_001179690.1\|4309853_4310681_-	rhamnulose-1-phosphate aldolase	NA	NA	NA	NA
WP_001661624.1\|4310823_4312083_-	L-rhamnose isomerase	NA	NA	NA	NA
WP_023197765.1\|4312079_4313549_-	rhamnulokinase	NA	NA	NA	NA
WP_000217112.1\|4313836_4314673_+	HTH-type transcriptional activator RhaS	NA	NA	NA	NA
WP_000013291.1\|4314825_4315674_+	HTH-type transcriptional activator RhaR	NA	NA	NA	NA
WP_000063541.1\|4315670_4316705_-	L-rhamnose/proton symporter RhaT	NA	NA	NA	NA
WP_000378721.1\|4317323_4318007_+	hypothetical protein	NA	NA	NA	NA
WP_000566800.1\|4318164_4319472_-	TRAP transporter large permease	NA	NA	NA	NA
WP_001091413.1\|4319464_4319980_-	TRAP transporter small permease	NA	NA	NA	NA
WP_000812816.1\|4319998_4320982_-	TRAP transporter substrate-binding protein	NA	NA	NA	NA
WP_097361573.1\|4321310_4321931_+	superoxide dismutase [Mn]	Q56AR7	Bacillus_thuringiensis_phage	3.2e-63	58.9
WP_011233226.1\|4321937_4322690_+	6-N-hydroxylaminopurine resistance protein	NA	NA	NA	NA
WP_021294276.1\|4322701_4323097_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_000580402.1\|4323147_4324521_-	envelope stress sensor histidine kinase CpxA	W8CYF6	Bacillus_phage	7.2e-15	25.6
WP_001033731.1\|4324517_4325216_-	envelope stress response regulator transcription factor CpxR	Q6XM27	Feldmannia_irregularis_virus	5.3e-06	30.3
WP_001233463.1\|4325366_4325867_+	cell-envelope stress modulator CpxP	NA	NA	NA	NA
4325892:4325936	attL	NA	NA	NA	NA
WP_079953016.1\|4326043_4327024_-\|integrase	tyrosine-type recombinase/integrase	A0A0M4RTQ0	Salmonella_phage	1.5e-184	97.9
WP_099706372.1\|4327093_4327447_-	helix-turn-helix transcriptional regulator	A0A0M5M1I9	Salmonella_phage	1.2e-59	100.0
WP_024153929.1\|4327518_4327980_+	hypothetical protein	NA	NA	NA	NA
WP_000422421.1\|4327930_4328386_-	hypothetical protein	NA	NA	NA	NA
WP_031607754.1\|4328524_4328806_+	hypothetical protein	A0A0M4RCW1	Salmonella_phage	1.4e-50	100.0
WP_000078935.1\|4328816_4329020_+	hypothetical protein	A0A0M3ULI0	Salmonella_phage	1.2e-30	98.5
WP_000290619.1\|4329030_4329237_+	DUF4761 family protein	A0A0M5M1I3	Salmonella_phage	4.3e-33	100.0
WP_000543629.1\|4329226_4329457_+	hypothetical protein	A0A0M4S6M9	Salmonella_phage	1.2e-28	76.0
WP_000482341.1\|4329551_4329986_+	tellurite resistance TerB family protein	Q1MVI3	Enterobacteria_phage	5.1e-68	91.0
WP_000946669.1\|4329985_4330168_+	hypothetical protein	NA	NA	NA	NA
WP_000166617.1\|4330211_4330424_+	hypothetical protein	A0A0M4R514	Salmonella_phage	6.4e-32	95.7
WP_000620901.1\|4330425_4331307_+	Dam family site-specific DNA-(adenine-N6)-methyltransferase	A0A0M4QWR0	Salmonella_phage	6.6e-131	82.3
WP_097361544.1\|4331306_4331504_+	hypothetical protein	NA	NA	NA	NA
WP_000128157.1\|4331504_4332539_+	DNA cytosine methyltransferase	A0A0M3ULA1	Salmonella_phage	5.6e-129	61.9
WP_058648989.1\|4332535_4334896_+	replication endonuclease	A0A0M4RTM8	Salmonella_phage	0.0e+00	86.1
WP_024153925.1\|4334971_4335565_+	hypothetical protein	NA	NA	NA	NA
WP_024153924.1\|4335578_4336691_+	ImmA/IrrE family metallo-endopeptidase	B6SBZ6	Clostridium_virus	4.4e-31	31.1
WP_000014576.1\|4337093_4338143_-\|portal	phage portal protein	A0A0M5M1H6	Salmonella_phage	6.7e-207	100.0
WP_024153923.1\|4338143_4339856_-	oxidoreductase	A0A0M4S6K7	Salmonella_phage	0.0e+00	98.6
WP_024153922.1\|4340009_4340855_+\|capsid	GPO family capsid scaffolding protein	A0A1J0I2E9	Salmonella_phage	1.4e-154	98.2
WP_001246220.1\|4340895_4341942_+\|capsid	phage major capsid protein, P2 family	A0A0M3ULA3	Salmonella_phage	3.7e-197	99.7
WP_044144072.1\|4341984_4342833_+\|terminase	terminase	A0A0M4R523	Salmonella_phage	4.7e-134	96.5
WP_024153920.1\|4342935_4343424_+\|head	head completion/stabilization protein	A0A0M4QWR7	Salmonella_phage	1.5e-84	96.9
WP_001102549.1\|4343423_4343624_+\|tail	tail protein	A0A0M4RTN6	Salmonella_phage	1.8e-31	100.0
WP_000543937.1\|4343634_4343970_+\|holin	phage holin, lambda family	A0A0M3ULH4	Salmonella_phage	2.1e-53	98.2
WP_024153919.1\|4343953_4344394_+	lysozyme	A0A0M5M782	Salmonella_phage	1.4e-76	97.9
WP_024153918.1\|4344494_4345025_+	DUF2514 family protein	A0A0M4S5V1	Salmonella_phage	7.4e-45	93.8
WP_000917105.1\|4345024_4345519_+\|tail	phage tail protein	A0A0M4R2U5	Salmonella_phage	8.7e-80	98.0
WP_058648991.1\|4345479_4346124_+	phage virion morphogenesis protein	A0A0M4RCU1	Salmonella_phage	2.8e-115	96.7
WP_097361545.1\|4346280_4346910_+\|plate	phage baseplate assembly protein V	A0A0M3ULA5	Salmonella_phage	9.3e-111	97.6
WP_000108899.1\|4346906_4347269_+\|plate	baseplate assembly protein	A0A0M4S6L5	Salmonella_phage	3.3e-60	99.2
WP_024153915.1\|4347265_4348177_+\|plate	baseplate assembly protein	A0A0M4REB7	Salmonella_phage	7.0e-160	97.7
WP_097361546.1\|4348169_4348784_+\|tail	phage tail protein I	A0A1J0I2I4	Salmonella_phage	1.9e-108	97.9
WP_044144047.1\|4348773_4350510_+\|tail	phage tail protein	A0A0M3ULH6	Salmonella_phage	3.6e-197	74.8
WP_024153912.1\|4350509_4351079_+\|tail	tail fiber assembly protein	A0A0M4RTP2	Salmonella_phage	6.0e-101	95.2
WP_024153911.1\|4351283_4351733_-\|tail	phage tail protein	A0A1J0I2L5	Salmonella_phage	2.5e-78	97.3
WP_024153910.1\|4351743_4354671_-\|tail	phage tail tape measure protein	A0A0M4R2V3	Salmonella_phage	0.0e+00	92.5
WP_000763324.1\|4354671_4354788_-\|tail	GpE family phage tail protein	A0A0M3ULA8	Salmonella_phage	6.6e-15	100.0
WP_000047593.1\|4354796_4355132_-	hypothetical protein	A0A0M4RCV2	Salmonella_phage	3.0e-52	99.1
WP_001207579.1\|4355146_4355662_-\|tail	phage major tail tube protein	A0A0M5M1I5	Salmonella_phage	3.9e-91	95.9
WP_000224787.1\|4355674_4356868_-\|tail	tail protein	A0A0M4S6M1	Salmonella_phage	1.0e-214	94.2
WP_024153908.1\|4357025_4358144_+	phage late control D family protein	A0A0M4REC6	Salmonella_phage	3.8e-192	99.5
WP_001251454.1\|4358192_4358435_+	ogr/Delta-like zinc finger family protein	NA	NA	NA	NA
WP_001077320.1\|4358685_4359588_+	CDF family cation-efflux transporter FieF	NA	NA	NA	NA
4358563:4358607	attR	NA	NA	NA	NA
WP_000591793.1\|4359772_4360735_+	ATP-dependent 6-phosphofructokinase	NA	NA	NA	NA
WP_000758711.1\|4360938_4361928_+	sulfate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000750756.1\|4362028_4362784_+	CDP-diacylglycerol diphosphatase	NA	NA	NA	NA
WP_000777314.1\|4363048_4364383_+	MFS transporter	NA	NA	NA	NA
WP_021294116.1\|4364393_4365353_+	aminoimidazole riboside kinase	NA	NA	NA	NA
WP_000557881.1\|4365362_4366403_+	ADP-ribosylglycohydrolase family protein	NA	NA	NA	NA
WP_001535809.1\|4366465_4367188_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000060999.1\|4367285_4367456_+	hypothetical protein	NA	NA	NA	NA
WP_000621105.1\|4367471_4367603_+	hypothetical protein	NA	NA	NA	NA
WP_001173083.1\|4367692_4368043_-	cupin domain-containing protein	NA	NA	NA	NA
WP_000113085.1\|4368056_4369649_-	autoinducer-2 kinase	NA	NA	NA	NA
WP_023197763.1\|4369735_4370695_-	transcriptional regulator LsrR	NA	NA	NA	NA
WP_001167255.1\|4370950_4372486_+	autoinducer 2 ABC transporter ATP-binding protein LsrA	A0A2H4PQG7	Staphylococcus_phage	8.3e-20	29.5
WP_000911133.1\|4372479_4373523_+	autoinducer 2 ABC transporter permease LsrC	NA	NA	NA	NA
WP_000981826.1\|4373519_4374521_+	autoinducer 2 ABC transporter permease LsrD	NA	NA	NA	NA
WP_000090737.1\|4374549_4375572_+	autoinducer 2 ABC transporter substrate-binding protein LsrB	NA	NA	NA	NA
WP_000774146.1\|4375600_4376476_+	3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase	NA	NA	NA	NA
WP_001738619.1\|4376558_4376849_+	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase	NA	NA	NA	NA
WP_001088050.1\|4376858_4377623_+	epimerase	NA	NA	NA	NA
WP_001216335.1\|4377714_4378482_-	triose-phosphate isomerase	NA	NA	NA	NA
WP_000802241.1\|4378594_4379191_-	YiiQ family protein	NA	NA	NA	NA
WP_000155237.1\|4379291_4379720_+	DUF805 domain-containing protein	NA	NA	NA	NA
WP_000796303.1\|4379826_4380573_-	ferredoxin--NADP(+) reductase	NA	NA	NA	NA
WP_001250624.1\|4380669_4381680_-	class II fructose-bisphosphatase	NA	NA	NA	NA
WP_000136809.1\|4381791_4383300_-	glycerol kinase GlpK	NA	NA	NA	NA
WP_000084285.1\|4383320_4384166_-	aquaporin	M1HWZ0	Paramecium_bursaria_Chlorella_virus	2.0e-15	28.6
WP_000051370.1\|4384564_4384804_+	septal ring assembly protein ZapB	NA	NA	NA	NA
WP_000872918.1\|4385025_4385511_-	ribonuclease E activity regulator RraA	NA	NA	NA	NA
WP_000139639.1\|4385603_4386533_-	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
WP_001293360.1\|4386599_4387931_-	HslU--HslV peptidase ATPase subunit	W6AS21	Erwinia_phage	2.4e-44	28.3
WP_000208240.1\|4387940_4388471_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA

DBSCAN-SWA_10

4507088 : 4525240

Burkholderia_phage(40.0%)

tail,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001177097.1\|4507088_4507604_-\|tail	tail fiber assembly protein	A0A0U2QV64	Escherichia_phage	3.4e-34	41.2
WP_000368203.1\|4507613_4509095_-\|tail	tail fiber protein	A0A0M3ULF6	Salmonella_phage	1.3e-51	51.7
WP_000359500.1\|4509097_4509730_-\|tail	phage tail protein I	Q6QI98	Burkholderia_phage	6.6e-24	56.4
WP_020437568.1\|4509722_4510838_-\|plate	phage baseplate	Q6QI99	Burkholderia_phage	3.4e-100	51.7
WP_001093501.1\|4510828_4511188_-\|plate	baseplate protein	Q6QIA0	Burkholderia_phage	2.8e-35	64.2
WP_000632048.1\|4511351_4512899_-	hypothetical protein	B9UDL6	Salmonella_phage	2.5e-48	29.9
WP_020437570.1\|4512898_4513828_-	glycosyltransferase family 2 protein	S5FKN0	Shigella_phage	3.9e-150	83.8
WP_000593184.1\|4513824_4514187_-	GtrA family protein	U5P0S6	Shigella_phage	9.6e-44	70.8
WP_017465888.1\|4514514_4515237_-\|plate	phage baseplate assembly protein V	A0A067ZIM2	Vibrio_phage	3.9e-12	42.0
WP_017465889.1\|4515246_4516290_-	phage late control D family protein	A4JWL3	Burkholderia_virus	6.5e-77	45.9
WP_001269716.1\|4516277_4516487_-	membrane protein	A4JWL2	Burkholderia_virus	9.8e-17	60.3
WP_020437572.1\|4516486_4517440_-	hypothetical protein	A4JWL1	Burkholderia_virus	1.0e-36	51.5
WP_153789630.1\|4517439_4519791_-\|tail	phage tail tape measure protein	A4JWL0	Burkholderia_virus	2.4e-66	31.2
WP_001185655.1\|4519887_4520016_-\|tail	GpE family phage tail protein	NA	NA	NA	NA
WP_020437574.1\|4519975_4520293_-\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_020437575.1\|4520344_4520869_-\|tail	phage major tail tube protein	Q6QIA9	Burkholderia_phage	3.6e-68	69.5
WP_000729853.1\|4520868_4522296_-\|tail	phage tail sheath family protein	A4JWK5	Burkholderia_virus	1.4e-194	70.9
WP_097361551.1\|4522285_4522483_-	hypothetical protein	Q6QIB1	Burkholderia_phage	5.6e-06	51.0
WP_000449439.1\|4522479_4522935_-	hypothetical protein	NA	NA	NA	NA
WP_000777267.1\|4523093_4523408_-	hypothetical protein	Q6QIC4	Burkholderia_phage	8.3e-20	48.2
WP_020437576.1\|4523420_4524026_-	transglycosylase SLT domain-containing protein	Q5ZQZ1	Pseudomonas_phage	1.4e-60	59.9
WP_001226439.1\|4524028_4524316_-	membrane protein	Q6QIC8	Burkholderia_phage	3.0e-16	48.1
WP_000615248.1\|4524892_4525240_+	DNA-binding protein	Q6QIE8	Burkholderia_phage	4.9e-21	51.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP045058

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP045059

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection