CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP035194	Klebsiella pneumoniae strain LH102-A chromosome, complete genome	3 crisprs	DinG,DEDDh,csa3,cas3,WYL	0	0	4	0
NZ_CP035195	Klebsiella pneumoniae strain LH102-A plasmid pLH102-A, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP035194_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP035194_1

2151851-2152253

Orphan

Consensus_repeat	Method
CTGACCGATAAGCCGCGTTCTTTTGGTATAGCGTCGTGGACAGTCATTCATCCTT	PILER-CR

3 spacers

The CRISPR arrays of NZ_CP035194_1

>merge|NZ_CP035194|1|2151851-2152253|PILER-CR
CTGACCGATAAGCCGCCTTCTTTTGGTATAGCGTCGTGGACAGCCATTCATCCGCGTCACGGGTTCAGATAGCAAAAACCCCGCCGGAGCGGGGTTTTGACATAAAAAAGGTGAAACTGACCGATAAGCCGCGTTCTTTTGGTATAGCGTCGTGGACAGTCATTCATCCTTTATCCGCTATTCGAATAGCAAAAACCCCGCCGTAGCGGAGTTTTGACATAAAAAGGTGAAACTGACCGATAAGCCGCGTTCTTTTGGTATAGCGTCGTGGACAGTCATTCATCCTTTCTCCGCTATTCGAATAGCAAAAACCCCGCCGTAGCGGGGTTTTGACATAAAAAGGTGAAACTGACCGATAAGCCGCGTTCTTTTGGTATAGCGTCGTGGACAGTCATTCATCCTT

>NZ_CP035194|1|1|2151851-2152253|PILER-CR
CTGACCGATAAGCCGCCTTCTTTTGGTATAGCGTCGTGGACAGCCATTCATCCGC	GTCACGGGTTCAGATAGCAAAAACCCCGCCGGAGCGGGGTTTTGACATAAAAAAGGTGAAA
CTGACCGATAAGCCGCGTTCTTTTGGTATAGCGTCGTGGACAGTCATTCATCCTT	TATCCGCTATTCGAATAGCAAAAACCCCGCCGTAGCGGAGTTTTGACATAAAAAGGTGAAA
CTGACCGATAAGCCGCGTTCTTTTGGTATAGCGTCGTGGACAGTCATTCATCCTT	TCTCCGCTATTCGAATAGCAAAAACCCCGCCGTAGCGGGGTTTTGACATAAAAAGGTGAAA
CTGACCGATAAGCCGCGTTCTTTTGGTATAGCGTCGTGGACAGTCATTCATCCTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP035194.1\|WP_004144878.1\|2159140_2160004_-\|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase	unknown	unknown	gnl\|CDD\|184956
NZ_CP035194.1\|WP_152659755.1\|2157368_2158940_+\|galactarate-dehydratase	unknown	unknown	gnl\|CDD\|274491
NZ_CP035194.1\|WP_004144873.1\|2154847_2155618_-\|2-dehydro-3-deoxyglucarate-aldolase	unknown	unknown	gnl\|CDD\|182547
NZ_CP035194.1\|WP_004144865.1\|2148693_2149590_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176122
NZ_CP035194.1\|WP_023288017.1\|2160067_2162176_+\|penicillin-binding-protein-activator	unknown	unknown	gnl\|CDD\|225649
NZ_CP035194.1\|WP_002918211.1\|2162545_2163136_+\|DnaA-initiator-associating-protein-DiaA	unknown	unknown	gnl\|CDD\|182811
NZ_CP035194.1\|WP_004149907.1\|2150661_2151072_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226203
NZ_CP035194.1\|WP_048333143.1\|2146055_2146352_+\|membrane-protein	unknown	unknown	gnl\|CDD\|372871
NZ_CP035194.1\|WP_002917923.1\|2148283_2148652_+\|DUF805-domain-containing-protein	unknown	unknown	gnl\|CDD\|225694
NZ_CP035194.1\|WP_048333145.1\|2153930_2154821_-\|2-hydroxy-3-oxopropionate-reductase	unknown	unknown	gnl\|CDD\|183197
NZ_CP035194.1\|WP_002917920.1\|2146697_2147090_+\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168
NZ_CP035194.1\|WP_002917917.1\|2145660_2146059_+\|membrane-protein	unknown	unknown	gnl\|CDD\|227681
NZ_CP035194.1\|WP_004149910.1\|2152720_2153866_-\|glycerate-2-kinase	unknown	unknown	gnl\|CDD\|182392
NZ_CP035194.1\|WP_048333144.1\|2149694_2150396_+\|pirin-family-protein	unknown	unknown	gnl\|CDD\|224655
NZ_CP035194.1\|WP_002917922.1\|2147170_2148157_+\|glutathione-S-transferase-family-protein	unknown	unknown	gnl\|CDD\|223512
NZ_CP035194.1\|WP_142891052.1\|2157036_2157261_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP035194.1\|WP_002918206.1\|2162133_2162520_+\|YraN-family-protein	unknown	unknown	gnl\|CDD\|237119
NZ_CP035194.1\|WP_002917916.1\|2145352_2145658_+\|DUF883-domain-containing-protein	unknown	unknown	gnl\|CDD\|226941
NZ_CP035194.1\|WP_004150939.1\|2151379_2151844_+\|OB-fold-putative-lipoprotein	unknown	unknown	gnl\|CDD\|378982
NZ_CP035194.1\|WP_004149911.1\|2155644_2156976_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|273326

Protein	Function_ID	Function_description	E-value
NZ_CP035194.1\|WP_004144878.1\|2159140_2160004_-\|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase	gnl\|CDD\|184956	PRK14994, PRK14994, SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional.	0
NZ_CP035194.1\|WP_152659755.1\|2157368_2158940_+\|galactarate-dehydratase	gnl\|CDD\|274491	TIGR03248, galactar-dH20, galactarate dehydratase. Galactarate dehydratase converts D-galactarate to 5-dehydro-4-deoxyglucarate which is subsequently acted on by GarL, tartronate semialdehyde reductase and glycerate kinase (GenProp0714).	0
NZ_CP035194.1\|WP_004144873.1\|2154847_2155618_-\|2-dehydro-3-deoxyglucarate-aldolase	gnl\|CDD\|182547	PRK10558, PRK10558, alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional.	0
NZ_CP035194.1\|WP_004144865.1\|2148693_2149590_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176122	cd08431, PBP2_HupR, The C-terminal substrate binding domain of LysR-type transcriptional regulator, HupR, which regulates expression of the heme uptake receptor HupA; contains the type 2 periplasmic binding fold. HupR, a member of the LysR family, activates hupA transcription under low-iron conditions in the presence of hemin. The expression of many iron-uptake genes, such as hupA, is regulated at the transcriptional level by iron and an iron-binding repressor protein called Fur (ferric uptake regulation). Under iron-abundant conditions with heme, the active Fur repressor protein represses transcription of the iron-uptake gene hupA, and prevents transcriptional activation via HupR. Under low-iron conditions with heme, the Fur repressor is inactive and transcription of the hupA is allowed. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.52e-52
NZ_CP035194.1\|WP_023288017.1\|2160067_2162176_+\|penicillin-binding-protein-activator	gnl\|CDD\|225649	COG3107, LppC, Putative lipoprotein [General function prediction only].	8.48289e-121
NZ_CP035194.1\|WP_002918211.1\|2162545_2163136_+\|DnaA-initiator-associating-protein-DiaA	gnl\|CDD\|182811	PRK10886, PRK10886, DnaA initiator-associating protein DiaA; Provisional.	2.29713e-142
NZ_CP035194.1\|WP_004149907.1\|2150661_2151072_-\|hypothetical-protein	gnl\|CDD\|226203	COG3678, CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein [Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism].	8.17264e-19
NZ_CP035194.1\|WP_048333143.1\|2146055_2146352_+\|membrane-protein	gnl\|CDD\|372871	pfam13997, YqjK, YqjK-like protein. The YqjK-like protein family includes the E. coli YqjK protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 100 amino acids in length. There is a single completely conserved residue R that may be functionally important.	4.5597e-23
NZ_CP035194.1\|WP_002917923.1\|2148283_2148652_+\|DUF805-domain-containing-protein	gnl\|CDD\|225694	COG3152, COG3152, Predicted membrane protein [Function unknown].	1.36085e-39
NZ_CP035194.1\|WP_048333145.1\|2153930_2154821_-\|2-hydroxy-3-oxopropionate-reductase	gnl\|CDD\|183197	PRK11559, garR, tartronate semialdehyde reductase; Provisional.	0
NZ_CP035194.1\|WP_002917920.1\|2146697_2147090_+\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	2.0965e-24
NZ_CP035194.1\|WP_002917917.1\|2145660_2146059_+\|membrane-protein	gnl\|CDD\|227681	COG5393, COG5393, Predicted membrane protein [Function unknown].	1.16468e-44
NZ_CP035194.1\|WP_004149910.1\|2152720_2153866_-\|glycerate-2-kinase	gnl\|CDD\|182392	PRK10342, PRK10342, glycerate kinase I; Provisional.	0
NZ_CP035194.1\|WP_048333144.1\|2149694_2150396_+\|pirin-family-protein	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	2.25995e-64
NZ_CP035194.1\|WP_002917922.1\|2147170_2148157_+\|glutathione-S-transferase-family-protein	gnl\|CDD\|223512	COG0435, ECM4, Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP035194.1\|WP_002918206.1\|2162133_2162520_+\|YraN-family-protein	gnl\|CDD\|237119	PRK12497, PRK12497, YraN family protein.	6.84829e-53
NZ_CP035194.1\|WP_002917916.1\|2145352_2145658_+\|DUF883-domain-containing-protein	gnl\|CDD\|226941	COG4575, ElaB, Uncharacterized conserved protein [Function unknown].	8.38471e-36
NZ_CP035194.1\|WP_004150939.1\|2151379_2151844_+\|OB-fold-putative-lipoprotein	gnl\|CDD\|378982	pfam12869, tRNA_anti-like, tRNA_anti-like. This is a family of bacterial, archeael and viral proteins that is related to the tRNA_anti family pfam01336. The major characteristic of families like tRNA_anti is their OB-fold, and many of them bind DNA.	3.01553e-44
NZ_CP035194.1\|WP_004149911.1\|2155644_2156976_-\|MFS-transporter	gnl\|CDD\|273326	TIGR00893, Probable_glucarate_transporter, D-galactonate transporter. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	4.0154e-131

>NZ_CP035194.1|WP_004150939.1|2151379_2151844_+|OB-fold-putative-lipoprotein
MLLRFRVLPLVFVISLLSGCGLASKAFYSAGDKLFQPGDDAVASMQTYSVAQFLQPFTLNPAKASSDYLGKWVKVRGVIVDIRRKSGIAGSYYFIVTMRDEQNKTDKRLTFNFGSHNSADVEALSNGSVATIVGQVHQVQDSTIPTLQNPKVVK
>NZ_CP035194.1|WP_004149907.1|2150661_2151072_-|hypothetical-protein
MKLITRIAFATLLTTGFSITAQAADVKAAPAPAQDPIVQHLKLTNDQVAKIKSLHQQLESNVQQISQQEIKDGALINVIDSGKWDEKAVNDQLAAFSKIDQQVRYYRVKYYFEVNKVLTPEQRTQVKKDLADALSE
>NZ_CP035194.1|WP_048333144.1|2149694_2150396_+|pirin-family-protein
MITTRTAKQCGQADFGWLQARYTFSFGHYFDPKLLGFASLRVLNQEVLAPGASFQARTYPKVDILNLILEGEAEYRDSDGNHMQAKAGEALLIATQPGVSYSEHNLSKEQSLTRMQLWLDACPQRENPLQQKINVADATLQLLASPEGGDNSLQLRQQAWVYHIALEKGEQINVQLHGPRAYLQSIHGSVHAVAQEQQKQALTCGDGAFIRDEANITLVADTPLRALLIDLPV
>NZ_CP035194.1|WP_004144865.1|2148693_2149590_-|LysR-family-transcriptional-regulator
MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQKLEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALSRGWETHLTIVTEALVPTPDLFPLIEKLATKSNTQLSIITEVLAGAWERLEQGRADIVVAPDMHFRSSSEINSRKLYSVLSVYVAAPDHPIHQEPEPLSEVTRVKYRGVAVADTARERPVLTVQLLDKQPRLTVSTIEDKRQALLAGLGVATMPYPLVEKDIAEGRLRVVSPEYTNEIDIIMAWRRDSMGEAKSWCLREIPKLFAGR
>NZ_CP035194.1|WP_002917923.1|2148283_2148652_+|DUF805-domain-containing-protein
MDWYLKVLKNYIGFGGRARRKEYWMFILVNLILTGVLSIIDKMLGWQRAGGEGILTTIYGVLVFLPWWAVQFRRLHDTDRSAWWLLLLLIPVIGWLVILIFNCQRGTEGNNRFGPDPKPFSY
>NZ_CP035194.1|WP_002917922.1|2147170_2148157_+|glutathione-S-transferase-family-protein
MGQLVDGVWQDTWYDTKSTGGRFKRSVSAFRNWLTADGAAGPSGEGGFAAEKDRYHLYVSLACPWAHRTLIMRKLKGLEPFLPVSVVNPLMLENGWTFDDSFPEATGDTLYQHDFLYQLYLHADPHYTGRVTVPVLWDKKQQTIVSNESAEIIRMFNTAFDGLGARAGDYYPPALREQIDELNGWIYDNVNNGVYKAGFATSQQAYDEAVDAVFTSLERLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKRRISDYLNLYGFLRDIYQMPGIAETVSFPHIRHHYYRSHKTINPTGIISIGPQQDLNEPHGRDQRFR
>NZ_CP035194.1|WP_002917920.1|2146697_2147090_+|DoxX-family-protein
MKKLEDVGVLVARILMPILFITAGWGKITGYAGTQQYMEAMGVPGALLPLTILLEFGGGLAILFGFLTRTTALFTAGFTLLTAFLFHSNFAEGVNSLMFMKNLTIAGGYLLLAITGPGAFSIDRVLNKKW
>NZ_CP035194.1|WP_048333143.1|2146055_2146352_+|membrane-protein
MNGRQERERQKTQLLRQIQQQRLELSACRRHWHEATAPFDRGWHTLLSLRSWLMVGSGLMAVWSVRHPHFLMRWTKRGLGLWSTWRLVRGILRQSAVR
>NZ_CP035194.1|WP_002917917.1|2145660_2146059_+|membrane-protein
MANTQHTQGPGQRVFSIGQRIVTLLVEMVETRLRLVVVELEEEKANLFQLLIMTGLTLLFAAFGLMSLLVLVIWAVDAQYRLHVMIATTVVLLLAAAIVGILTLRKARRSTLLRLTRKELENDRALLEEDKS
>NZ_CP035194.1|WP_002917916.1|2145352_2145658_+|DUF883-domain-containing-protein
MAKENVTDDLRAELKTLADTLEEVLNSSADKSKEEMGKLRSKAESALKESRARLGETSEAILRQTRETAARADDYVRENPWTGVGIGAAVGLVLGVLLSRR
>NZ_CP035194.1|WP_004149910.1|2152720_2153866_-|glycerate-2-kinase
MKIVIAPDSYKESLSASEVAQAIEKGFREIFPDAQYVSLPVADGGEGTVEAMIAATQGKEHFAWVTGPLGERVKACWGMSGDGVTAFIEMAAASGLGLVPPDKRNPLITTSRGTGELILQALEHGAERIIIGIGGSATNDGGAGMMQALGARLCDAEGQEIGHGGGSLSRLSRIDLSAIDPRLRDRMIHVACDVTNPLVGERGASRIFGPQKGATEAMIVELDRNLAHYADVIKTSLQVDVKSIPGAGAAGGMGAALMAFLNAELRSGIEIVTEALKLEEQIHDCSLVVTGEGRLDSQSVHGKVPVGVARVAKKYRKPVIGIAGSLTHDVGVVHQHGIDAVFSVLTSVSTLEEAFRGAFDNIYRASRNIAATLQVGMTTEG
>NZ_CP035194.1|WP_048333145.1|2153930_2154821_-|2-hydroxy-3-oxopropionate-reductase
MTIKVGFIGLGIMGKPMSKNLLKAGYSLVVSDRNPEAIADVIAAGAETATTPKAIAEQCEVIITMLPNSPHVKEVALGENGIIEGAKPGTVVIDMSSIAPLASREISEALKAKGIDMLDAPVSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGDIGAGNVTKLANQVIVALNIAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLDAKAPMVMDRNFKPGFRIDLHIKDLANALDTSHGVDAQLPLTAAVMEMMQALRADGLGTADHSALACYYEKLAKVEVTR
>NZ_CP035194.1|WP_004144873.1|2154847_2155618_-|2-dehydro-3-deoxyglucarate-aldolase
MDNAIFPNKFKAALAAHQVQIGCWCALANPISTEVLGLAGFDWLVLDAEHAPNDVTTLIPQLMALKGSSSAQVVRVPTNEPIIIKRMLDIGFYNFLVPFVETAEQAAQAVASTRYPPEGIRGVSVSHRGNMFGTVPDYFAQSNKNISILVQIESQTGVDNVEAIAATEGVDGVFVGPSDLAAALGHLGNASHPEVQRAIQHIFASAKKHGKPSGILAPVEADARRYLEWGATFVAVGSDLGVFRSATQKLADAFKK
>NZ_CP035194.1|WP_004149911.1|2155644_2156976_-|MFS-transporter
MILDSTLDEKKGIPTRYLILLMIFVVTAVNYGDRATLSIAGTEVAKELGLSAVSMGYIFSAFGWAYLLMQIPGGWLLDKFGSKKVYSYSLFFWSLFTFLQGFIDVFPLAWAGVSMFFMRFMLGFSEAPSFPANARIVAAWFPAKERGTASAIFNAAQYFSLALFSPLLGWLTFALGWEHVFTVMGIIGFVLTIIWVKFVHNPTDHPRMSAAELKYISEGGAVVDMDHKKEATPAAGPKMDYIRQLLTNRMMLGVFFGQYFLNTITWFFLTWFPIYLVQDKGMSILKVGFVASIPALFGFAGGVLGGLFSDYLIGRGCTLTFARKLPIVLGMLLASSIILCNYTASTPLVITLMALAFFGKGFGALGWPVISDVAPKEIVGLCGGVFNVFGNVASIATPLVIGYIVSELHSFNGALIFVGGSALMMMVCYLFVVGDIKRMELQK
>NZ_CP035194.1|WP_142891052.1|2157036_2157261_-|hypothetical-protein
MIVITPFYDANLCRAGNRKKCGLAPMTYGISTIMALNNKFILWVCIVSGGGVLIILSHVFEVIDMRIDSFNIVF
>NZ_CP035194.1|WP_152659755.1|2157368_2158940_+|galactarate-dehydratase
MADIAIRQQWPTAFYIKVDPTDNVAIIVNDRGLTAGTRFPDGLTLVEHIPQGHKVALVDIPAHGEIIRYGEVIGYAVRDIPQGSWIDESLVELPTAPPLNTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPNYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNIALNPNFGGEVMVIGLGCEKLQPERLLQGTEDVKSIPVDSASIVSLQDEKHVGFKSMVDDILQVAERHLAKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAINEEVGKRLLEEMAWYDNYLDMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWYDLMDINAGTIATGEETIEDVGRKLFEFILDVASGRKKTFSDQWGLHNQLAVFNPAPVT
>NZ_CP035194.1|WP_004144878.1|2159140_2160004_-|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase
MKQHESADNSQGQLYIVPTPIGNLSDITQRALEVLQAVDLIAAEDTRHTGLLLQHFAINARLFALHDHNEQQKAETLLAKLKEGQNIALVSDAGTPLINDPGYHLVRTCREANIRVVPLPGPCAAIAALSAAGLPSDRFCYEGFLPAKSKGRRDTLKALEEEPRTLIFYESTHRLVESLEDICAVLGESRYVVLARELTKTWESIHGAPIGELVAWVKEDENRRKGEMVLIVEGFKAQEEALPAAALRTLALLQAELPLKKAAALAAEIHGVKKNALYKYALEQQGE
>NZ_CP035194.1|WP_023288017.1|2160067_2162176_+|penicillin-binding-protein-activator
MVPSTFLRSKPARCLPVLLATLIFAGCGTHTQDQSAAFMQGTSQANSSFYLQQMQQSTNDSKTNWQLLAIRALLQEGKKQQAIDLFNQLPANLNSTQAREQSLLAVEVKLAQNDYQAARNLLAKIDPTNLEQPQQARYWQAQIDASQGKPSLTLLRALIAQQPLLSDAKQRQKNIDATWQALTSMPQDQANALVINADENILQGWLDLQRMWFDNRNDPTLLKAGVKDWQTRYPQNPGAKMLPTALVNMQNYKPASINKIALFLPLNGQASIFGRTIQQGFEAAKNGAPSVTGSAVPAQVAQAANVSGNDDVVSPSQAEISDLTAAGSRADPVQAPTQDQAAPAAEPAAQAPATSATPQTTASPATQPVTAPAAQPQPVVATAANPSAELKIYDTTSQPISQLLAQAQQDGATLVVGPLLKENVEEVIKSNTPLNVLALNQPEKVESRANLCYFALSPEDEARDAARHIHQQGKQTPLLLVPRGALGDRVVSAFADEWLKLGGASVLQQRFGSTAELRAGVNGGGGIALSGTPVSTLPSAQNSILGSADEMPVSSGGSVDAAYILATPEQIAYIKPMIAMRNGSQSNVTLYASSRSAQGTAGPDFRLEMEGLQYSEIPMLAGSNPSLMQQALSAVRNDYSLARLYAMGADAWSLANHFTQMRQTPGFELNGNTGDLTANQDCVINRKLSWLKYQQGKIVPAS
>NZ_CP035194.1|WP_002918206.1|2162133_2162520_+|YraN-family-protein
MAQVPAGKNRSGQLSKQTGDAWENQARRWLEGQGLRFIAANARERGGEIDLIMRDGTVTVFIEVRYRRSARYGDAAASVTPQKQQRLLKAARLWLCRQNGSFETVDCRFDVVAFTGNDIQWLKNAFGE
>NZ_CP035194.1|WP_002918211.1|2162545_2163136_+|DnaA-initiator-associating-protein-DiaA
MLDRIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPGLPAIALNTDNVVLTAIANDRLHDEIYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGQQDVEIRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDD

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Crispr_ID: NZ_CP035194_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP035194_2

3571167-3571252

Orphan

Consensus_repeat	Method
AATAAAAACCATAAAAACCACAGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP035194_2

>merge|NZ_CP035194|2|3571167-3571252|CRISPRCasFinder
AATAAAAACCATAAAAACCACAGTCATAAATCAGAGATATATCACTCCCGGGCAGTTCAGCGAATAAAAACCATAAAAACCATAGT

>NZ_CP035194|2|1|3571167-3571252|CRISPRCasFinder
AATAAAAACCATAAAAACCACAGT	CATAAATCAGAGATATATCACTCCCGGGCAGTTCAGCG
AATAAAAACCATAAAAACCATAGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP035194.1\|WP_002888353.1\|3579806_3580502_-\|L-ribulose-5-phosphate-4-epimerase	unknown	unknown	gnl\|CDD\|236181
NZ_CP035194.1\|WP_004145972.1\|3584199_3585045_+\|arabinose-operon-transcriptional-regulator-AraC	unknown	unknown	gnl\|CDD\|236717
NZ_CP035194.1\|WP_004192048.1\|3569399_3571025_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225827
NZ_CP035194.1\|WP_002888373.1\|3585173_3585941_+\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP035194.1\|WP_002888320.1\|3560141_3560621_+\|type-3-dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|182714
NZ_CP035194.1\|WP_002888327.1\|3562923_3563913_-\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696
NZ_CP035194.1\|WP_004147026.1\|3565259_3567608_-\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158
NZ_CP035194.1\|WP_002888345.1\|3571349_3572714_+\|2-hydroxycarboxylate-transporter-family-protein	unknown	unknown	gnl\|CDD\|377030
NZ_CP035194.1\|WP_002888324.1\|3562105_3562927_-\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP035194.1\|WP_002888332.1\|3567851_3568679_+\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512
NZ_CP035194.1\|WP_004178574.1\|3574179_3577086_-\|RNA-polymerase-associated-protein-RapA	unknown	unknown	gnl\|CDD\|235319
NZ_CP035194.1\|WP_094316103.1\|3577273_3579631_-\|DNA-polymerase-II	unknown	unknown	gnl\|CDD\|235595
NZ_CP035194.1\|WP_002888329.1\|3563918_3565205_-\|peptidylprolyl-isomerase-SurA	unknown	unknown	gnl\|CDD\|236758
NZ_CP035194.1\|WP_011977646.1\|3582152_3583862_-\|ribulokinase	unknown	unknown	gnl\|CDD\|235221
NZ_CP035194.1\|WP_004145980.1\|3573507_3574167_-\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	unknown	unknown	gnl\|CDD\|236659
NZ_CP035194.1\|WP_004182906.1\|3568711_3569410_-\|response-regulator	unknown	unknown	gnl\|CDD\|226931
NZ_CP035194.1\|WP_002888321.1\|3560872_3561721_-\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)	unknown	unknown	gnl\|CDD\|273208
NZ_CP035194.1\|WP_004177424.1\|3580639_3582142_-\|L-arabinose-isomerase	unknown	unknown	gnl\|CDD\|179503
NZ_CP035194.1\|WP_002888347.1\|3572893_3573433_+\|citrate-lyase-holo-[acyl-carrier-protein]-synthase	unknown	unknown	gnl\|CDD\|163145
NZ_CP035194.1\|WP_002888323.1\|3561725_3562103_-\|Co2+/Mg2+-efflux-protein-ApaG	unknown	unknown	gnl\|CDD\|180098

Protein	Function_ID	Function_description	E-value
NZ_CP035194.1\|WP_002888353.1\|3579806_3580502_-\|L-ribulose-5-phosphate-4-epimerase	gnl\|CDD\|236181	PRK08193, araD, L-ribulose-5-phosphate 4-epimerase AraD.	0
NZ_CP035194.1\|WP_004145972.1\|3584199_3585045_+\|arabinose-operon-transcriptional-regulator-AraC	gnl\|CDD\|236717	PRK10572, PRK10572, arabinose operon transcriptional regulator AraC.	0
NZ_CP035194.1\|WP_004192048.1\|3569399_3571025_-\|sensor-histidine-kinase	gnl\|CDD\|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	7.63459e-173
NZ_CP035194.1\|WP_002888373.1\|3585173_3585941_+\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	1.35562e-48
NZ_CP035194.1\|WP_002888320.1\|3560141_3560621_+\|type-3-dihydrofolate-reductase	gnl\|CDD\|182714	PRK10769, folA, type 3 dihydrofolate reductase.	1.71656e-127
NZ_CP035194.1\|WP_002888327.1\|3562923_3563913_-\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0
NZ_CP035194.1\|WP_004147026.1\|3565259_3567608_-\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0
NZ_CP035194.1\|WP_002888345.1\|3571349_3572714_+\|2-hydroxycarboxylate-transporter-family-protein	gnl\|CDD\|377030	pfam03390, 2HCT, 2-hydroxycarboxylate transporter family. The 2-hydroxycarboxylate transporter family is a family of secondary transporters found exclusively in the bacterial kingdom. They function in the metabolism of the di- and tricarboxylates malate and citrate, mostly in fermentative pathways involving decarboxylation of malate or oxaloacetate.	4.87969e-169
NZ_CP035194.1\|WP_002888324.1\|3562105_3562927_-\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	3.65731e-147
NZ_CP035194.1\|WP_002888332.1\|3567851_3568679_+\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	2.63694e-164
NZ_CP035194.1\|WP_004178574.1\|3574179_3577086_-\|RNA-polymerase-associated-protein-RapA	gnl\|CDD\|235319	PRK04914, PRK04914, RNA polymerase-associated protein RapA.	0
NZ_CP035194.1\|WP_094316103.1\|3577273_3579631_-\|DNA-polymerase-II	gnl\|CDD\|235595	PRK05762, PRK05762, DNA polymerase II; Reviewed.	0
NZ_CP035194.1\|WP_002888329.1\|3563918_3565205_-\|peptidylprolyl-isomerase-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	0
NZ_CP035194.1\|WP_011977646.1\|3582152_3583862_-\|ribulokinase	gnl\|CDD\|235221	PRK04123, PRK04123, ribulokinase; Provisional.	0
NZ_CP035194.1\|WP_004145980.1\|3573507_3574167_-\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	gnl\|CDD\|236659	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA.	7.90078e-161
NZ_CP035194.1\|WP_004182906.1\|3568711_3569410_-\|response-regulator	gnl\|CDD\|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	1.65624e-65
NZ_CP035194.1\|WP_002888321.1\|3560872_3561721_-\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)	gnl\|CDD\|273208	TIGR00668, Bis5'-nucleosyl-tetraphosphatase_symmetrical, bis(5'-nucleosyl)-tetraphosphatase (symmetrical). Diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) is a regulatory metabolite of stress conditions. It is hydrolyzed to two ADP by this enzyme. Alternate names include diadenosine-tetraphosphatase and Ap4A hydrolase. [Cellular processes, Adaptations to atypical conditions].	0
NZ_CP035194.1\|WP_004177424.1\|3580639_3582142_-\|L-arabinose-isomerase	gnl\|CDD\|179503	PRK02929, PRK02929, L-arabinose isomerase; Provisional.	0
NZ_CP035194.1\|WP_002888347.1\|3572893_3573433_+\|citrate-lyase-holo-[acyl-carrier-protein]-synthase	gnl\|CDD\|163145	TIGR03124, citrate_citX, holo-ACP synthase CitX. Members of this protein family are the CitX protein, or CitX domain of the CitXG bifunctional protein, of the citrate lyase system. CitX transfers the prosthetic group 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA to the citrate lyase gamma chain, an acyl carrier protein. This enzyme may be designated holo-ACP synthase, holo-citrate lyase synthase, or apo-citrate lyase phosphoribosyl-dephospho-CoA transferase. In a few genera, including Haemophilus, this protein occurs as a fusion protein with CitG (2.7.8.25), an enzyme involved in prosthetic group biosynthesis. This CitX family is easily separated from the holo-ACP synthases of other enzyme systems. [Energy metabolism, Fermentation, Protein fate, Protein modification and repair].	5.54697e-86
NZ_CP035194.1\|WP_002888323.1\|3561725_3562103_-\|Co2+/Mg2+-efflux-protein-ApaG	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	7.84855e-74

>NZ_CP035194.1|WP_004192048.1|3569399_3571025_-|sensor-histidine-kinase
MKLSFQYKLFISLVAFFSVLFIALGIYYYFDASRQLYQEMSARAKIQAEEIALMPNLRQQVSRHDPQAIQAFMQQIAAHSDASFIVIGDRQGVHLFHSVHPEWVGTRLVGGDNQAVLEGKSITTIRKGGLGVSLRSKTPIVDDAGRVIGIVSVGYLTSYLDSITLTKVINIFIAAVLLLIALFIFSWYFTRSIKKQIFSLEPREIGLLVRQQKAMMESIFEGVIVIDRQRRIEVINHAARSLLGLSQPARQLRGQSIDSVISPQPFFASGDMLERDTHDELCRFNQLTVLASRVRIMLENTLQGWVITFRDRNEINALTAQLSQVKRYVDNLRIMRHEQLNRMTTLSGLLHMGHYDEAIRYIQAQSEHAQELLDFISSHFHSPTLCGLLLGKATRAREKGVALSFDPACRIDRPLPSLMESELISIIGNLLDNAIEATQRAELPHEPVEVLIQLNARELIIEVADRGVGIRPDIRERIFERGVTTKTRGDHGIGLYLIEHYVTQAGGTIEVADNAPRGTIFTLFIPADAHACPQPEVHDAS
>NZ_CP035194.1|WP_004182906.1|3568711_3569410_-|response-regulator
MHHDLVDVLIIEDESELARLHAELVQKHPRLRLAGMAASLAQARQLLHATPPQLVLLDNYLPDGKGVTLMTDPALATSQCSVIFITAASDMETCSQAIRNGAFDYILKPVSWKRLSQSLERFIQFYDQQREWKIVDQQNVDSLYQLQAKNYRVDSGSKGIEEKTLALVQGLFSGREAHCFSVDEVVSAAGLSKTTARRYLEHGVETGFLEVEMLYGKIGHPRRLYRRAKVKS
>NZ_CP035194.1|WP_002888332.1|3567851_3568679_+|co-chaperone-DjlA
MQYLGKVIGVAVALLMGGGFWGVVLGFLVGHMFDRARSRRLNLFANQQERQSLFFSTTFEVMGHLTKSKGRVTEADIHVANVLMDRMNLHGASRTAAQQAFRDGKADNYPLREKMRQLRSVCFGRFDLIRMFLEIQLQAAFADGELHPNEREVLFVIADELGISRAQFDQFLRMMQGGAQFGGGSQQRSYGQHGGNAGWQQAQRGPTLEDACNVLGVKPTDDAATVKRAYRKLMNEHHPDKLVAKGLPPEMMEMAKQKAQEIQKAWELIKEQRGF
>NZ_CP035194.1|WP_004147026.1|3565259_3567608_-|LPS-assembly-protein-LptD
MKKRIPSLLATMIASALYSQQGLAADLATQCMLGVPSYDRPLVEGRPGDLPVTINADHAKGNYPDNAVFTGNVDINQGNSRLRADEVQLHQQQAAGQAQPVRTVDALGNVHYDDNQVILKGPKAWSNLNTKDTNVWQGDYQMVGRQGRGTADLMKQRGENRYTILENGSFTSCLPGSDTWSVVGSEVIHDREEQVAEIWNARFKLGSVPIFYSPYLQLPVGDKRRSGFLIPNAKYSTKNGVEFSLPYYWNIAPNFDATITPHYMNKRGGVMWENEFRYLTQLGSGLTEFDYLPSDKVYEDDHSSDSNSRRWLFYWNHSGVIDQVWRLNADYTKVSDPDYFNDFSSKYGSSTDGYATQKFSAGYVNQNFDATVSTKQFQVFDRESSNSYSAEPQLDVNYYQNDVGPFDTHLYGQVAHFVNSNNNMPEATRVHFEPTINLPLSNGWGSLNTEAKLLATHYQQSNLDKYNAANGTDYKESVSRVMPQFKVDGKMVFERDLQEGFTQTLEPRVQYLYVPYRDQSEIGNYDSTLLQSDYTGLFRDRTYSGLDRIASANQVTTGLTSRVYDAAAVERFNISVGQIYYFTESRTGDDNINWENNDTTGSLVWAGDTYWRIADEWGLRGGIQYDTRLDNVATGNGTIEYRRDENRLVQLNYRYASPEYIQATLPSYSTAAQYKQGISQVGMTASWPIVDRWSVVGAYYYDTNTRKAANQMLGVQYNSCCYAIRLGYERKVNGWNSNDNGGESKYDNTFGINIELRGLSSNYGLGTQQMLRSNILPYQSSL
>NZ_CP035194.1|WP_002888329.1|3563918_3565205_-|peptidylprolyl-isomerase-SurA
MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAGQAGQQLPDDATLRHQILERLIMDQIVLQMGQKMGVKISDDQLDQAIANIAKQNNMTLDQMRSRLAYEGINYNTYRNQIRKEMLISEVRNNEVRRRITVLPQEVEALAKQIGDQNDASTELNLSHILIPLPENPTSDEVAAAQEQANSIVEQARNGANFGKLAITYSADQQALKGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGGTQNISVTEVHARHILLKPSPIMNDAQAQAKLEQIAAEIKSGKITFAQAAKTYSEDPGSANQGGDLGWATPDIFDPAFRDALMRLNKGQTSGPVHSSFGWHLIELLDSRQVDRTDAAQKDRAYRMLMNRKFSEEAATWMQEQRASAYVKILSN
>NZ_CP035194.1|WP_002888327.1|3562923_3563913_-|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MPETRKVVITPGEPAGIGPDLVVQLAQRDWPVELVICADGALLTDRAKRLGLPLSLLPYDPAQPPVPQRAGTLTLLNVPLNVPAEPGVLNVQNGAYVVETLARACDGCLSGEFAALVTGPVHKGNINDAGIAFTGHTEFFEERAKASKVVMMLATEELRVALVTTHLPLKAISEAITPELLREIITILDHDLRTKFGIAQPHVLVCGLNPHAGEGGHMGTEEIDTIIPVLEEMRAKGMNLSGPLPADTLFQPKYLDHADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGQGKADVGSFITALNLAIKMIVNTQ
>NZ_CP035194.1|WP_002888324.1|3562105_3562927_-|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTMNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCQVIPVLEVPPSAFTPPPKVDSAVVRLVPHSTMPYPVKEIRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTELGIDPAMRAENISVAQYCLMANWLSDNLPTKES
>NZ_CP035194.1|WP_002888323.1|3561725_3562103_-|Co2+/Mg2+-efflux-protein-ApaG
MIHSPRVCVQVQSVYIESQSSPEEERYVFAYTVTIRNLGRSQVQLLGRYWLITNGHGRETEVQGEGVVGEQPHIPAGGEYQYTSGAVIETPLGTMQGHYEMIDIDGAPFRIEIPVFRLAVPTLIH
>NZ_CP035194.1|WP_002888321.1|3560872_3561721_-|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)
MSTYLIGDVHGCYDELIALLAQVEFDPRRDTLWLTGDLVARGPGSLEVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLKPLLEAPDADELLNWLRRQPLLQVDEEKKLVMAHAGITPQWDLETAQQCARDVEAVLSSDSYPFFLDAMYGDMPNHWSNELSGLARLRFISNAFTRMRYCFPNGQLDMYSKEAPEDAPAPLKPWFAIPGPVSNAYSIAFGHWASLEGRGTPEGIYALDTGCCWGGELTCLRWEDKQYFTQPSNRQKSLDEGEAVAS
>NZ_CP035194.1|WP_002888320.1|3560141_3560621_+|type-3-dihydrofolate-reductase
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRLTWESIGRPLPGRKNIVISSKPGSDDRVQWVSSVEEAIAACGDVEEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYDPDEWESVFSEFHDADAQNSHSYCFEILERR
>NZ_CP035194.1|WP_002888345.1|3571349_3572714_+|2-hydroxycarboxylate-transporter-family-protein
MSTTDNAFSATLEPIDTPKTTLKQRWWHIMDNWKVGIVPLPLFLLAGGLIALDCLGGKLPSDIVVMVATLAFFGFACGEFGKRLPVLGKLGAAAICATFIPSALVHYGLLPDVVIESTTKFYKSTNILYLYICCIIVGSIMSMNRTTLIQGFLKIFFPMLCGEVVGMLVGIGVGTLLGMEPFQVFFFIVLPIMAGGVGEGAIPLSMGYAALMHMEQGVALGRVLPMVMLGSLTAIVISGCLNQLGKRFPHLTGEGQLMPNRSHETRSLSESEGVSGKTDVGTLASGALLAVLLYMMGMLGHKLIGLPAPVGMLFLAVLLKLANVVSPRLQEGSQMVYKFFRTAVTYPILFAVGVAITPWQELVNAFTLTNLLVIVSTVSALVATGFLVGKKIGMHPIDVAIVSCCQSGQGGTGDVAILTAGNRMSLMPFAQIATRIGGAINVSLGLLFLSHYLA
>NZ_CP035194.1|WP_002888347.1|3572893_3573433_+|citrate-lyase-holo-[acyl-carrier-protein]-synthase
MSVDTPAQAGVSIDALLAAKEQRAARQADWLAHYQQPVISLTLVTPGAVKDSIRYRNMMGVALQACDQLLWKHRWQTLDRQVLWLPTGPEALWCVAHPASEIKAMCSTLEQSHPLGRLWDIDVICPQNGLVGRQSLGESQRRCLLCDEPAHACARSRRHDTDLVVARVEQMIDAWFARD
>NZ_CP035194.1|WP_004145980.1|3573507_3574167_-|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA
MAMENYNPPQDPWLVILYQDEHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDFPQAESVHRLDMATSGVIVVALNKAAERELKRQFREREPKKQYVARVWGHPQPAEGLVDLPLICDWPNRPMQKVCYETGKAAQTEYEVLEYAEDNTARVRLKPITGRSHQLRVHMLALGHPILGDRFYATPEALAMAPRLLLHAETLTITHPAYGNAMTFRAPIDF
>NZ_CP035194.1|WP_004178574.1|3574179_3577086_-|RNA-polymerase-associated-protein-RapA
MPFTLGQRWISDTESELGLGTVVALDARMVTLLFPAIGENRLYSRNDSPITRVMFNPGDTITSHEGWQLHVDKVNEENGLLSYTGTRLDTQEANVTLREVLLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKFQSEQYRMPWSGLRGQRTSLIPHQLHIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIVVPETLQHQWLVEMLRRFNLRFSLFDDERYAEAQHDAYNPFETEQLVICSLDFVRRSKQRLEHLCDAEWDLMVVDEAHHLVWSEEAPSREYQAIEQLAERVPGILLLTATPEQLGMESHFARLRLLDPNRFHDFEQFVEEQQNYRPVADAVALLLAGNKLSDSELNTLGDLIGEQDIEPLLQAANSDREDAQAARQELISMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIRLPLPTQYQTAIKVSGIMGARKTAEERARDMLYPEQIYQEFEGDTGTWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASNLVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTVYDSVHDELINYLAAPESTDGFDDLIKSCRQQHDALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTSLIAFSMNLFDIVGINQDDRGENLIVLTPSDHMLVPDFPGLPEDGCTITFERDVALSREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLLELIYVVEAQAPKQLQLNRFLPATPVRMLLDKNGNNLAAQVEFESFNRQLSAVNRHTGSKLVNAVQQDVHAILQQGEAQIAKAAQGLIDAARNEADEKLTAELSRLEALKAVNPNIRDDELAAIESNRQQVMDALAQAGWRLDALRLIVVTHQ
>NZ_CP035194.1|WP_094316103.1|3577273_3579631_-|DNA-polymerase-II
MTQPRAGFLLTRHWRDTPQGTELSFWLATDDGPLQVTLPPQESVAFIPEAQRAQAERLLQGEKGLRFAPLALKDFHRQPIVGLYCRAHRQLMRLEKMLRDSGVTVYEGDIRPPERYLMERFITAPVWVEGETRGSQLVNARMKPTPDYRPPLKWVSLDIETSRHGELYCIGLEGCGQRVVYMLGPEPETPPDVDFELVFIASRPLLLEKLNAWFAEHDPDVLIGWNVVQFDLRVLQKHAERYRIPLRLGRGNSELEWREHGFKNGVFFAQANGRLIIDGIDALKSAFWNFSSFSLEAVARELLGEGKAIDNPWDRMDEIDRRFHEDKPALAIYNLQDCELVTRIFHKTEIMPFLLERATVNGLPADRHGGSVAAFSHLYFPRMHRLGYVAPNLGDVPPQASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGLAQPDDQHSIEGFLGARFSRDKHCLPGIVSQIWHGRDEAKRQHNKPLSQALKIIMNAFYGVLGTSACRFFDPRLASSITMRGHAIMRQTKALIEAKGYDVIYGDTDSTFVWLKRPHSEAQAAEIGRELVSDVNAWWSQELSKSQLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGMIQEGDAQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNQPYQDYVRETIARLMNGELDEQLVYRKRLRRPLAEYQRNVPPHVRAARLADEHNLKLGRAQQYQQRGTIKYVWTTSGPEPVDYQQSPLDYDHYLTKQLQPVAEGILPFVNDDFATIVTGQLGLF
>NZ_CP035194.1|WP_002888353.1|3579806_3580502_-|L-ribulose-5-phosphate-4-epimerase
MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDREKGVFVIKPSGVDYRVMTADDMVVVSLESGEVVEGNKKPSSDTPTHRLLYQAFPTLGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGPVPCTRLMTDAEINGDYEWETGNVIVETFRQQGIDPAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEIAYMGIFCRQLAPQLPAMQQTLLDKHYLRKHGAKAYYGQ
>NZ_CP035194.1|WP_004177424.1|3580639_3582142_-|L-arabinose-isomerase
MTIFDNYEVWFVIGSQHLYGPEALRQVTKHAEHVVNSLNAEAKLPCKLVLKPLGTTPDEITHICRDANYDDKCAGLVVWLHTFSPAKMWINGLTILNKPLLQFHTQYNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHSVVTGHWQDKEAHQRIGGWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDISALVDEYESSYRLTPAAQVHGEKRQNVLDAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFDNGNDLVLGSHMLEVCPTIATAEKPILDVQPLGIGGKADPARLIFNTQTGPAIVASLIDLGDRFRLLVNTIETVPTPHDLPKLPVANALWKAQPDLRTASEAWIIAGGAHHTVFSHALNLDDMRQFAELHDIELTVIDNDTRLPSFKDALRWNEVYYGSKR
>NZ_CP035194.1|WP_011977646.1|3582152_3583862_-|ribulokinase
MAIAIGLDFGSDSVRALAVECASGAELATSVEWYPRWREGQYCDGANNRFRHHPRDYIESMEAALKSVLASLSAEQRADVVGIGVDSTGSTPAPVDAEGNVLALREEFADNPNAMFVLWKDHTAVEEAEAITRLCHQPGKEDYSRYIGGIYSSEWFWAKILHVTREDSAVAQAAASWVELCDWVPALLSGTTRPQDLRRGRCSAGHKSLWHESWGGLPPASFFDELDPIINQHLAWPLFTDTWTADVPVGTLSAEWAQRLGLSQSVAISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKESVGERTVKGICGQVDGSVVPHFIGMEAGQSAFGDIYAWFGRILGWPLEQLAQQQPALREQIKASQKQLLPALTEAWANNPSLEHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPALFGGLIAATAFGARAIMECFTEQGIPVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAGVYDDIPAAQQRMASQVETTLQPRPAQAQRFEQLYQRYQQWSVSAEQHYLPSAAKAEKAPQSQAALTH
>NZ_CP035194.1|WP_004145972.1|3584199_3585045_+|arabinose-operon-transcriptional-regulator-AraC
MAETQNDPLLPGYSFNAHLVTGLTPIEAQGYLDFFIDRPLGMKGYILNLTIRGEGVINNHGEQFVCRPGDMLLFPPGEIHHYGRHPDASEWYHQWVYFRPRAYWHEWLNWPTIFAQTGFFRPDEQWQARFGELFGQIVDAGQGAGRYSELLAINLLEQLLLRRMEAINESLHPPLDNRVRDACQYISDHLADSHFDIASVAQHVCLSPSRLSHLFRQQLGVSVLGWREDQRISQAKLLLSTTRMPIATVGRNVGFEDQLYFSRVFKKCTGASPSEFRAGCE
>NZ_CP035194.1|WP_002888373.1|3585173_3585941_+|DedA-family-protein
MQALLEHFITQSTVYSLLAVMLVAFLESLALVGLILPGTVMMAGLGALIGGGEVNFWQAWLAGIVGCLLGDWISFWLGWRFKKPLHRWSFMKKNRALLEKTEHALHQHSMITILIGRFVGPTRPLVPMVAGMLDLPVAKFVLPNIIGCLLWPPLYFLPGILAGAAIDIPADENSASFKWLLLGAALLAWLAGWLCWRLWRSAKTSGDRLTRWLPRGRLLWLSPLMVALAATALTFVFRHPLMPVYLAILHKVIAR

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Crispr_ID: NZ_CP035194_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP035194_3

4379526-4379608

Orphan

Consensus_repeat	Method
CCGTAGGCCGGGTAAGGCGTCAGCCGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP035194_3

>merge|NZ_CP035194|3|4379526-4379608|CRISPRCasFinder
CCGTAGGCCGGGTAAGGCGTCAGCCGCCACCCGGCAAAATAACCGCGCAATAGCACCGTAGGCCGGGCAAGGCGTCAGCCGCC

>NZ_CP035194|3|2|4379526-4379608|CRISPRCasFinder
CCGTAGGCCGGGTAAGGCGTCAGCCGCC	ACCCGGCAAAATAACCGCGCAATAGCA
CCGTAGGCCGGGCAAGGCGTCAGCCGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP035194.1\|WP_106516909.1\|4384744_4385467_+\|ATP-dependent-dethiobiotin-synthetase-BioD	unknown	unknown	gnl\|CDD\|234625
NZ_CP035194.1\|WP_004152853.1\|4385408_4386131_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223487
NZ_CP035194.1\|WP_002895580.1\|4381818_4382859_+\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|185063
NZ_CP035194.1\|WP_032414694.1\|4372411_4373368_+\|formimidoylglutamase	unknown	unknown	gnl\|CDD\|234974
NZ_CP035194.1\|WP_021441451.1\|4371197_4372415_+\|imidazolonepropionase	unknown	unknown	gnl\|CDD\|236478
NZ_CP035194.1\|WP_004142122.1\|4369657_4370941_-\|putative-acyl-CoA-thioester-hydrolase	unknown	unknown	gnl\|CDD\|236709
NZ_CP035194.1\|WP_004151699.1\|4374297_4375986_+\|urocanate-hydratase	unknown	unknown	gnl\|CDD\|235448
NZ_CP035194.1\|WP_071888018.1\|4386553_4386865_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP035194.1\|WP_152659815.1\|4383996_4384752_+\|malonyl-ACP-O-methyltransferase-BioC	unknown	unknown	gnl\|CDD\|182340
NZ_CP035194.1\|WP_002895575.1\|4379768_4380245_-\|kinase-inhibitor	unknown	unknown	gnl\|CDD\|182339
NZ_CP035194.1\|WP_002895358.1\|4373429_4374155_+\|histidine-utilization-repressor	unknown	unknown	gnl\|CDD\|184961
NZ_CP035194.1\|WP_004183465.1\|4366214_4366646_+\|universal-stress-protein-G	unknown	unknown	gnl\|CDD\|185353
NZ_CP035194.1\|WP_004147678.1\|4386841_4388863_+\|excinuclease-ABC-subunit-B	unknown	unknown	gnl\|CDD\|235395
NZ_CP035194.1\|WP_004176814.1\|4377607_4378990_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|182566
NZ_CP035194.1\|WP_004176804.1\|4382855_4384013_+\|8-amino-7-oxononanoate-synthase	unknown	unknown	gnl\|CDD\|235655
NZ_CP035194.1\|WP_004176805.1\|4380315_4381605_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|181189
NZ_CP035194.1\|WP_023284866.1\|4366697_4369385_+\|cation-transporting-P-type-ATPase	unknown	unknown	gnl\|CDD\|319775
NZ_CP035194.1\|WP_002895420.1\|4375982_4377509_+\|histidine-ammonia-lyase	unknown	unknown	gnl\|CDD\|236484
NZ_CP035194.1\|WP_004147662.1\|4364595_4365681_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NZ_CP035194.1\|WP_002895652.1\|4386217_4386430_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP035194.1\|WP_106516909.1\|4384744_4385467_+\|ATP-dependent-dethiobiotin-synthetase-BioD	gnl\|CDD\|234625	PRK00090, bioD, ATP-dependent dethiobiotin synthetase BioD.	4.14229e-105
NZ_CP035194.1\|WP_004152853.1\|4385408_4386131_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223487	COG0410, LivF, ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism].	3.17026e-74
NZ_CP035194.1\|WP_002895580.1\|4381818_4382859_+\|biotin-synthase-BioB	gnl\|CDD\|185063	PRK15108, PRK15108, biotin synthase; Provisional.	0
NZ_CP035194.1\|WP_032414694.1\|4372411_4373368_+\|formimidoylglutamase	gnl\|CDD\|234974	PRK01722, PRK01722, formimidoylglutamase; Provisional.	1.94479e-179
NZ_CP035194.1\|WP_021441451.1\|4371197_4372415_+\|imidazolonepropionase	gnl\|CDD\|236478	PRK09356, PRK09356, imidazolonepropionase; Validated.	0
NZ_CP035194.1\|WP_004142122.1\|4369657_4370941_-\|putative-acyl-CoA-thioester-hydrolase	gnl\|CDD\|236709	PRK10531, PRK10531, putative acyl-CoA thioester hydrolase.	0
NZ_CP035194.1\|WP_004151699.1\|4374297_4375986_+\|urocanate-hydratase	gnl\|CDD\|235448	PRK05414, PRK05414, urocanate hydratase; Provisional.	0
NZ_CP035194.1\|WP_004147678.1\|4386841_4388863_+\|excinuclease-ABC-subunit-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP035194.1\|WP_152659815.1\|4383996_4384752_+\|malonyl-ACP-O-methyltransferase-BioC	gnl\|CDD\|182340	PRK10258, PRK10258, biotin biosynthesis protein BioC; Provisional.	3.9312e-160
NZ_CP035194.1\|WP_002895575.1\|4379768_4380245_-\|kinase-inhibitor	gnl\|CDD\|182339	PRK10257, PRK10257, putative kinase inhibitor protein; Provisional.	7.58373e-117
NZ_CP035194.1\|WP_002895358.1\|4373429_4374155_+\|histidine-utilization-repressor	gnl\|CDD\|184961	PRK14999, PRK14999, histidine utilization repressor; Provisional.	3.37417e-172
NZ_CP035194.1\|WP_004183465.1\|4366214_4366646_+\|universal-stress-protein-G	gnl\|CDD\|185353	PRK15456, PRK15456, universal stress protein UspG; Provisional.	1.69931e-44
NZ_CP035194.1\|WP_004176814.1\|4377607_4378990_+\|amino-acid-permease	gnl\|CDD\|182566	PRK10580, proY, putative proline-specific permease; Provisional.	0
NZ_CP035194.1\|WP_004176804.1\|4382855_4384013_+\|8-amino-7-oxononanoate-synthase	gnl\|CDD\|235655	PRK05958, PRK05958, 8-amino-7-oxononanoate synthase; Reviewed.	0
NZ_CP035194.1\|WP_004176805.1\|4380315_4381605_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl\|CDD\|181189	PRK07986, PRK07986, adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated.	0
NZ_CP035194.1\|WP_023284866.1\|4366697_4369385_+\|cation-transporting-P-type-ATPase	gnl\|CDD\|319775	cd02080, P-type_ATPase_cation, P-type cation-transporting ATPase similar to Exiguobacterium aurantiacum Mna, an Na(+)-ATPase, and Synechocystis sp. PCC 6803 PMA1, a putative Ca(2+)-ATPase. This subfamily includes the P-type Na(+)-ATPase of an alkaliphilic bacterium Exiguobacterium aurantiacum Mna and cyanobacterium Synechocystis sp. PCC 6803 PMA1, a cation-transporting ATPase which may translocate calcium. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP035194.1\|WP_002895420.1\|4375982_4377509_+\|histidine-ammonia-lyase	gnl\|CDD\|236484	PRK09367, PRK09367, histidine ammonia-lyase; Provisional.	0
NZ_CP035194.1\|WP_004147662.1\|4364595_4365681_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	6.18674e-67

>NZ_CP035194.1|WP_004176814.1|4377607_4378990_+|amino-acid-permease
MQQQHKPHLLRGLNARHIRFIALGSAIGTGLFYGSASAIKAAGPAVLLAYLIGGAAVFIVMRALGEMAVRNPVSGSFGSYARQYLGPLAGFITGWTYTFEMVIVALADVTAFGIYMGLWYPDVPRWIWILSIIFFIGAMNLCNVRVFGEMEFWLSLVKVVAIIAMMLAGAGIIFFGFGHSFPATGLENLWSHGGFAPNGWQGVIASLGIVMFAFGGVEIIGVTAAEAKDPKKVIPQAINTIPLRIILFYVCTLAVLMAIFPWNSFGEQGSPFVLIFDGLGIPAAATILNIIVISASISAINSDIFGAGRMMYGMSKEGLAPKSFQRIASNSVPWMTVVVMGGALLAAVVLNYLIPEQVFVLIASLAAFATVWVWLMILLSHFAMRRGLSAEERSQIAFPIPFWPVAPLLTLLFMGLVIAVLGMFAETRMALIAGLVWLGLLTVVWYARVRKTALQVVTEQ
>NZ_CP035194.1|WP_002895420.1|4375982_4377509_+|histidine-ammonia-lyase
MKSLTLIPGQLSLSQLRDVYSHPVNITLDSGAFAAIDESVACVNAILAEGRTAYGINTGFGLLAQTRISTEDLENLQRSLVLSHAAGVGEPLDDDLTRLIMVLKINSLSRGFSGIRLSVIQALIGLVNAGVTPWIPAKGSVGASGDLAPLAHMSLTLLGEGKARVRGGEWLPATEALRQVGLEPITLAAKEGLALLNGTQASTAFALRGLFEAEDLFASAVVCGALTTEAALGSRRPFDARIHEVRGQRGQIDAAALYRHLLTDDSAISQSHHNCSKVQDPYSLRCQPQVMGACLTQIRQAAEVLLAEANAVSDNPLVFAAENDVISGGNFHAEPVAMAADNIALAIAEIGSLSERRIALMMDSHMSQLPPFLVKNGGVNSGFMIAQVTAAALASENKALSHPHSVDSLPTSANQEDHVSMAPAAGRRLWAMAENTRGVLAVEWLAAAQGLDMREGLTTSPLLEEARHLLRERVPHYTQDRYFAPDIDNAIALLAARHLTRLLPAVLH
>NZ_CP035194.1|WP_004151699.1|4374297_4375986_+|urocanate-hydratase
MSQSKYRQLDVRAPRGTTLTAKSWLTEAPLRMLMNNLDPDVAENPHELVVYGGIGRAARNWECYDAIVKALKNLESDETLLVQSGKPVGVFKTHENSPRVLIANSNLVPHWATWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHYQGSLKGRWVLTAGLGGMGGAQPLAATLAGACSLNIECQQSRIDFRLRTRYVDEQATSLDDALARIKKYTAEGRAISIALCGNAAEIVPELVKRGVRPDMVTDQTSAHDPLHGYLPKGWSWEEYQQKAESDPQGTILAAKRSMADHVQAMLAFHEMGVPTFDYGNNIRQMAQEVGVSNAFDFPGFVPAYIRPLFCRGIGPFRWVALSGDPQDIYKTDAKVKEIIKDDQHLHHWLDMARERISFQGLPARICWVGLEWRQKLGLAFNEMVRSGEVSAPIVIGRDHLDSGSVASPNRETEAMRDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHSGMVIVCDGTDEAAARIARVLHNDPATGVMRHADAGYEIAIECAAEQGLNLPMVAATQGNAK
>NZ_CP035194.1|WP_002895358.1|4373429_4374155_+|histidine-utilization-repressor
MFAQQPRSAPAPFYEKVKQAISEKIHSGVWRPHDRIPSEAELVAQFGFSRMTINRALRELTDEGLLVRLQGVGTFVAEPKGQSALFEVRSIAAEIVARHHQHRCEVLLLEETRADHIQATALSVPEGTRIFHSLMVHYENEVPVQIEDRCVNAAVVPDYLHQDYTATTPHDYLSLIAPLTEGEHIVEAVQATAEECALLHIHAHDPCLLIRRRTWSTTHIVSHARLLFPGSRYRLQGRFGS
>NZ_CP035194.1|WP_032414694.1|4372411_4373368_+|formimidoylglutamase
MMLWQATPASLWQGRDDSAEAPNALRLFQTIARAERFAPQEMPGDIALLGFACDEGVRRNKGRTGAADGPATLRRALANMASHQGHDRCVDMGTISVDGEQLEAAHQALREAVAACQRAGKRTLVLGGGHETAFGHGAGVLDAFPGEKVGIINLDAHLDLRFAECASSGTPFRQLALECEAQQRGFHYTCIGVSRAANTQALWDEAARRQVAIVEDLEVLAAFETRVLPELERNIAQFDRLYLTIDLDVLPAREMPAVSAPAALGVPLATLLRIVEPLCRSGKLQAVDLVEFNPLFDIDGQGARAAARVAWQIAHWWR
>NZ_CP035194.1|WP_021441451.1|4371197_4372415_+|imidazolonepropionase
MTEATSELVIWRNGRLATLNPDHAQPYGLLERHALLVRDGRIAAIVAEDDVPSGRSIDLEGRLVTPGLIDCHTHLVFGGSRAQEWEQRLNGVSYQTISASGGGINSTVRATRDSSEAELLALAQPRLERLLREGVTTLEIKSGYGLDLPNERKMLRVARQLADHNGVELSATLLSAHATPPEYQGDANGYITLVCETILPTLWQEGLFESVDVFCENVGFSPQQTERVFQAAQALGIPVKGHVEQLSSLGGAQLVSRYHGLSADHIEYLTEEGVAAMRESGTVAALLPGAFYFLNETRKPPVELLRKYQVPMAVATDFNPGTSPFASLHLAMNMACVKFGLTPEEAWAGVTRHAARALGRQASHGQLAPGFVANFAIWDAEHPVEMVYEPGRSPLWHRVVQGELQ
>NZ_CP035194.1|WP_004142122.1|4369657_4370941_-|putative-acyl-CoA-thioester-hydrolase
MNTYSVSRLALALAFGVTLSACSSTPADQQPSTQTAPGTTARPILNAEEAKNFTPAAYFQSLAPNAAAWTPSAISLPAQPDFIVGPAGTQGVTHTTIQAAVDAAIARHSNRRLYIAIMPGEYPGTVYVPAAPGALTLYGTGDKPIDVKISEAIDSEMDRNTWRRLVNPGGKYMPGKPAWYMFDSCQSKSAATVGVMCSAVFWSQNNGLQLQNLTIANNLGDSVDAGTHQAVALRSDGDQVQINKVNILGRQNTFFVTNSGVQNRLQDNRQTRTLVTNSYIEGDVDIVSGRGAVVFDNTDFRVVNSRTQKEAYVFAPATLKSVTYGFLATNSRFTASGDNVAQLGRALDVDGNSNGQVVIRDSAINEGFNIAQPWAAAVGSGRPFSGNTGSADDKGNLQRNLNDNGFNRMWEYNNRGVGSTVVAEPKQ
>NZ_CP035194.1|WP_023284866.1|4366697_4369385_+|cation-transporting-P-type-ATPase
MNTDKPGAPYYQRSVEETLASVQSSPEGISGTEAATRLQQYGENALPQKPGKPAWLRFIAHFNDVLIYVLLAAALLKAVMGHWIDMAVILAVAVVNALIGFIQESNAEKSLQSIRNMLSSEAVAIRQGNHETIPTTSLVPGDIVVIRAGDRIPADLRVIEAHNLRVEEAILTGESTVVEKTTEPLSGDLPLGDRSNLLFSGTTVSSGAGKGIVVATGGNTELGHINQMMAGIEKHRTPLLVQMDKLGKAIFILILVMMAALFVFSLLFRDMPVSELMLSLISLAVASVPEGLPAIISIILSLGVQAMARQKAIIRKLPTVETLGAMTVICSDKTGTLTMNEMTVKAVITADSVYRVEGDSYEPVGKIHAIDDPTPVTIAPGSLFERYLRTIDLCNDSQLIKEESGLWKITGGPTEGALKVLAAKVTLPPLTSELRSKIPFDSQYKYMSTLYRLGEEEVVLVTGAPDVLFRLCQYQQSDSGLQPLDLPYWEGKIEEYAREGLRMVAAAWKPAAAGQTELTHQDLQQGVILLGVAGMMDPPRPEAITAIADCLQAGIRVKMITGDHPQTAMSIGKMLGIGNAGNAITGRELEVMDDAQLSVAAQQFDIFARTSPEDKFRLVQALQSKKEIVGMTGDGVNDAPALKQADVGVAMGIKGTEVTKEAADMVLTDDNFATIASAVREGRRVYDNLKKTILFVMPTNLAQGLLIVIALLAGNVLPLTPVLILWMNMATSATLSFGLAFEAGEKNIMRRPPRDPKIHVMDGFAIWRVAFVGSMIAVSAFILEAWLQPRGYSPEFIRTVLLQTLVTAQWFYMLNCRVSDGFSLTKGLLANKGIWIVSGVLLLLQLLIIYAPFMQMLFGTTGLPFRYWVITFIIGFAMFLIVELEKPLTRKWRSA
>NZ_CP035194.1|WP_004183465.1|4366214_4366646_+|universal-stress-protein-G
MYKNIVVPVDVFDAGLADKALSHAKFLAQHSAGQIHLIHVIPAFSPVLTRGFISDARKMEDHLLNTAKEKLSELVKKNGLAEDASHLYVRSGNVRDQVIALADELKADVVIVGSRNPGIQTHLLGSEAANIVRYAHVPVFVVR
>NZ_CP035194.1|WP_004147662.1|4364595_4365681_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MNRYFSLIPVVIIFTTACDQKAPTVESAPRMVKVAQVTAVGNTQQRTFPARIESGDSTELSFKRGGQVESLDIRQGASVAQGQTLARLNAREAQQRVNERQTAATLAQRQFDRFQTLAGRQAISQAEMDVQRANRDAANAALKIAREELAQMSLIAPFSGIAAGVHIRNHQVVAAGQPVITLTRTDLLDVVFSIPENLFTSLDIRNTAYRPVVRINTLPGREFTAEYKEHTGSSDNSTLTWQIVLTMPRPDDFPAVGGVSGTVTVNLGNLPASAGRETLIVPAEAVFNPDNRPKNEPVVWVVKGDNAHRYLEERKVTVGEVTSQGVAITDGLRAGEQVVAAGVSELHAGQPVRVWTRERGL
>NZ_CP035194.1|WP_002895575.1|4379768_4380245_-|kinase-inhibitor
MKLISHDLQDGGKLPNRHVFNGMGYDGDNISPHLMWDDVPAGTKSFVVTCYDPDAPTGSGWWHWVVANLPADTRVLPQGAGSGQAELPEEAVQTRTDFGKAGYGGAAPPKGETHRYIFTVHALDVEKIEVDAEASGAMVGFNVHFHSLASASITALFS
>NZ_CP035194.1|WP_004176805.1|4380315_4381605_-|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MTLDDLAFDRRHIWHPYTSMTSPLPVYPVVSAHGCELSLAGGEQLVDGMSSWWAAIHGYNHPRLNAALKGQIDQMSHVMFGGITHPPAVALCRQLVAMTPASLECVFLADSGSVAVEVAMKMALQYWQAKGEPRRRFLTFRNGYHGDTFGAMSVCDPQNSMHSLWQGYLPDNLFAPAPQSRFDGEWDEMDMVPFARLMAAHRHEIAAVILEPIVQGAGGMRMYHPEWLKRVRKMCDREGILLIADEIATGFGRTGKLFACEHAGITADILCLGKALTGGTMTLSAAITTRTVAETISNGEAGCFMHGPTFMGNPLACAVASESLRLLESGEWQPQVAAIEAQLQAELAPARGSALVADVRVLGAIGVVETRRPVNMAALQRFFVEQGVWIRPFGRLIYLMPPYIITPEQLTRLTRAVNQAVQDETFFSE
>NZ_CP035194.1|WP_002895580.1|4381818_4382859_+|biotin-synthase-BioB
MAHQPRWTMSQVTELFNKPLIDLLFEAQQIHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSARYKTGLEAERLMEVEQVLESARQAKNAGSTRFCMGAAWKNPNDRDMPYLEQMVKGVKALGLESCMTLGTLTDSQAQRLAEAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLDKVRDAGIKVCSGGIVGLGESVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAIARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGINPQQTAVLEGDNEQQQRLEQALLTPDTEEYYNAAAL
>NZ_CP035194.1|WP_004176804.1|4382855_4384013_+|8-amino-7-oxononanoate-synthase
MSWQQRIDRALDERRAAEAFRRRLPVTHGAGRWLEREGERWLNFSSNDYLGLSQHPAIIAAWQQGATRYGVGAGGSGHVSGYSEAHRALEEALADWLGYPRALLFISGFAANQALIAALVEKDDRIVADRLSHASLLEAASLSPAQLRRFTHNDPQQLAQLLAKPLAGEQLAVTEGIFSMDGDSAPLAAIHAATQAAGAVLLVDDAHGVGVVGDEGRGSCAAQAVRPELLVVTFGKAFGVSGAAVLCDEAMADYLLQFARHLIYSTAMPPAQAVALSAALGIIRSDEGQQRRDILAARIRQFREGMGEVSLGLTDSVSAIQPLIVGDNARALNLACRLRDAGCWATAIRPPTVPVGSARLRLTLTAAHHAEDINRLLEVLHGHSE
>NZ_CP035194.1|WP_152659815.1|4383996_4384752_+|malonyl-ACP-O-methyltransferase-BioC
MATVNKQAVAAAFGRAASGYTQHDELQRRCADLLLRQLARRDFAQVLDAGCGPGSMSRYWREAGSVVTALDLSAGMLAQAQRNDAAQHYLLGDIEALPLPDACVDLAWSNLAVQWCDDLRAAIGELYRVARPGGRVAFSTLLADSLPELNQAWQAIDDRPHANRFLSEAAVRAALSGLRATGEVHQISLPFADALSAMRSLKGIGATHLHQGRTAAPLGRGKLREVQLAWPQRQGICPLTYSLFTGVIERD
>NZ_CP035194.1|WP_106516909.1|4384744_4385467_+|ATP-dependent-dethiobiotin-synthetase-BioD
MTKRFFVTGTDTEVGKTIASSALLQAANLLGFHTAGYKPVASGSELTGDGLRNEDALALQRHSRVALRYDQVNPYTFAEPTSPHIISADEGRPIAAARLSSGLRELEGLADWVLVEGAGGWFTPLSDSLTFADWVQAEQLPVILVVGVKLGCINHAMLTAQAVRQAGLPLAGWIANDVQPPGKRHAEYLATLKNRLAAPFLGEIPWLADIAQRDDLGQYLDLRALDPALSTAPAAAHPAP
>NZ_CP035194.1|WP_004152853.1|4385408_4386131_-|ATP-binding-cassette-domain-containing-protein
MLNLQAVNHFYGNQHSLWNVDLVLRPGECIGVLGREGMGKTTLVNCIAGHLPVASGRMTWHDIGAPPQDLTPLSAQSRSAIGIGYVPQDKRIFSQLSVEENLHIALAAGKPGANASGGEIYEHFPELYALRQRKGASLSDDDQYQLALARALIVQPRLLILDEPSRGRGPRCLQKLADLLLRLNRDIGLTVLLAEQHLPFIRRVADRFCVLHRGRNVAEGDIMALDEPLLAQWITPDPAP
>NZ_CP035194.1|WP_002895652.1|4386217_4386430_-|hypothetical-protein
MDNCPQPKTTAARRLSPFAVNRVAKNFYRTIFDNYPLKAARFLLLFAPPFSVGHRKSAAPALTRPDGIGV
>NZ_CP035194.1|WP_071888018.1|4386553_4386865_-|hypothetical-protein
MQYKRFTHQSEPEKRISGRCLILPPGPFFANKLYWIFKQCVLMITPQKGLIGRQAGCKTRVRRNNPPAARVIPRKFYLLTFVKRTDETFMAADDAFLTPIDFI
>NZ_CP035194.1|WP_004147678.1|4386841_4388863_+|excinuclease-ABC-subunit-B
MSKSFVLHSAFRPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKALLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMLIDQRAILRRLAELQYTRNDQAFQRGTFRVRGEVIDVFPAESDDIALRIELFDEEVERLSLFDPLTGHVEGTVPRYTIYPKTHYVTPRERIVQAMEEIKLELAERRKVLLANNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVIDESHVTVPQIGGMYRGDRARKETLVEYGFRLPSALDNRPMKFEEFEALAPQTIYVSATPGAYELDKSGGEVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRLRTAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQRYNEEHGIVPQGLNKKVVDILQLGQGLAKTKAKGRGKAKVVEPAGLSAVDMTPKALQQKIHELEGQMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

24550 : 35437

Escherichia_phage(87.5%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002210516.1\|24550_25171_-	aldolase	A0A077SK32	Escherichia_phage	8.0e-115	100.0
WP_004190239.1\|25163_26429_-	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	3.9e-233	99.5
WP_002903955.1\|26440_27343_-	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	2.6e-159	99.7
WP_004209817.1\|27603_28365_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	5.5e-134	99.6
WP_023282555.1\|28385_29246_-	class A extended-spectrum beta-lactamase SHV-27	A0A077SL40	Escherichia_phage	2.9e-155	99.3
WP_004183954.1\|29543_29804_+	hypothetical protein	A0A077SK33	Escherichia_phage	3.5e-40	97.7
WP_025368140.1\|29890_30979_+	AAA family ATPase	A0A077SLJ9	Escherichia_phage	1.4e-210	99.7
WP_004176258.1\|31009_32275_-	MFS transporter	NA	NA	NA	NA
WP_065804957.1\|32329_35437_-	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	59.6

DBSCAN-SWA_2

1028089 : 1034994

Bacillus_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004149058.1\|1028089_1029568_+	two-component system sensor histidine kinase BaeS	W8CYF6	Bacillus_phage	8.5e-30	28.3
WP_004175198.1\|1029564_1030287_+	two-component system response regulator BaeR	W8CYM9	Bacillus_phage	8.3e-31	33.2
WP_004144192.1\|1030605_1031967_+\|tRNA	tRNA 5-hydroxyuridine modification protein YegQ	Q6DW11	Phage_TP	1.8e-207	94.8
WP_002912636.1\|1032212_1033106_+	lipid kinase YegS	A0A1V0SBJ0	Catovirus	6.1e-15	29.8
WP_040027268.1\|1033346_1034120_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.9e-26	36.7
WP_004180551.1\|1034130_1034994_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.7e-10	27.5

DBSCAN-SWA_3

1234437 : 1315760

Enterobacteria_phage(14.58%)

plate,tail,tRNA,holin,terminase,head,integrase,portal,capsid,protease

attL 1257168:1257191|attR 1296739:1296762

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002913226.1\|1234437_1235250_-\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_002913227.1\|1235249_1236263_-	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_152659724.1\|1236326_1237463_-	4-phosphoerythronate dehydrogenase PdxB	A0A2R8FDS8	Brazilian_cedratvirus	1.6e-20	27.8
WP_021313698.1\|1237573_1238551_+	flagella biosynthesis regulator Flk	NA	NA	NA	NA
WP_004149211.1\|1238637_1239813_-	MFS transporter	NA	NA	NA	NA
WP_002913291.1\|1240022_1241243_-	beta-ketoacyl-ACP synthase I	NA	NA	NA	NA
WP_020317299.1\|1241401_1243390_+\|tRNA	bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	NA	NA	NA	NA
WP_002913338.1\|1243451_1243733_-	YfcL family protein	NA	NA	NA	NA
WP_002913339.1\|1243764_1244313_-	elongation factor P hydroxylase	NA	NA	NA	NA
WP_002913340.1\|1244312_1245122_-	TSUP family transporter	NA	NA	NA	NA
WP_004174960.1\|1245121_1245946_-	penicillin-insensitive murein endopeptidase	NA	NA	NA	NA
WP_009483974.1\|1245948_1247034_-	chorismate synthase	A0A291AU41	Pandoravirus	1.3e-88	46.4
WP_002913346.1\|1247075_1248008_-	50S ribosomal protein L3 N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_002913348.1\|1248175_1248727_+	endonuclease SmrB	NA	NA	NA	NA
WP_002913355.1\|1248747_1249233_-	phosphohistidine phosphatase SixA	NA	NA	NA	NA
WP_004149220.1\|1249442_1251587_-	fatty acid oxidation complex subunit alpha FadJ	NA	NA	NA	NA
WP_004185010.1\|1251586_1252897_-	acetyl-CoA C-acyltransferase FadI	NA	NA	NA	NA
WP_002913359.1\|1253056_1253341_-	DUF406 family protein	NA	NA	NA	NA
WP_004149222.1\|1253708_1255037_+	long-chain fatty acid transporter FadL	NA	NA	NA	NA
WP_002913362.1\|1255098_1255860_-	phospholipid-binding lipoprotein MlaA	NA	NA	NA	NA
WP_060415764.1\|1256149_1257079_+	formate/nitrite transporter family protein	E7DYY8	Enterobacteria_phage	3.0e-134	81.4
1257168:1257191	attL	NA	NA	NA	NA
WP_064182199.1\|1257285_1257657_-	hypothetical protein	K7PGV5	Enterobacterial_phage	2.1e-25	50.0
WP_064182198.1\|1257613_1257853_-	hypothetical protein	I6PD82	Cronobacter_phage	4.9e-20	53.2
WP_004892499.1\|1258266_1258689_-	hypothetical protein	K7P834	Enterobacteria_phage	1.8e-25	44.5
WP_133060760.1\|1259002_1259854_+	hypothetical protein	NA	NA	NA	NA
WP_040150096.1\|1260114_1260309_-	hypothetical protein	NA	NA	NA	NA
WP_064182196.1\|1261159_1261354_+	hypothetical protein	NA	NA	NA	NA
WP_152659836.1\|1261552_1263046_-	hypothetical protein	NA	NA	NA	NA
WP_152659725.1\|1263596_1266680_-	kinase	A0A286S259	Klebsiella_phage	0.0e+00	71.9
WP_021313617.1\|1266676_1267057_-	hypothetical protein	A0A286S2A6	Klebsiella_phage	2.1e-57	80.2
WP_023301978.1\|1267066_1267552_-	DUF1833 domain-containing protein	A0A286S2B1	Klebsiella_phage	4.0e-53	66.2
WP_023301979.1\|1267538_1268012_-	hypothetical protein	A0A286S298	Klebsiella_phage	4.6e-54	60.8
WP_038806630.1\|1268032_1271419_-\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	1.1e-303	58.0
WP_016530182.1\|1271479_1271713_-	hypothetical protein	K7PH16	Enterobacteria_phage	1.9e-08	47.2
WP_004177139.1\|1271786_1272092_-	DUF4035 domain-containing protein	Q9MCS5	Enterobacteria_phage	4.7e-28	64.6
WP_021313622.1\|1272094_1272499_-\|tail	phage tail protein	K7PKV6	Enterobacterial_phage	8.5e-33	57.7
WP_023313062.1\|1272529_1273234_-	immunoglobulin domain-containing protein	K7PHL2	Enterobacterial_phage	5.5e-80	66.9
WP_016530186.1\|1273290_1273638_-	DUF3168 domain-containing protein	K7PKL6	Enterobacterial_phage	2.8e-32	63.7
WP_019705270.1\|1273634_1274084_-	HK97 gp10 family phage protein	Q9MCS9	Enterobacteria_phage	6.7e-63	82.6
WP_019705271.1\|1274080_1274419_-\|head	phage head closure protein	A0A2H4JHK5	uncultured_Caudovirales_phage	6.6e-39	68.8
WP_019705272.1\|1274427_1274745_-\|head,tail	phage gp6-like head-tail connector protein	A0A1W6JNZ5	Morganella_phage	7.4e-24	52.9
WP_117271238.1\|1274822_1276061_-\|capsid	phage major capsid protein	Q8SBH8	Shigella_phage	1.6e-159	70.4
WP_000999827.1\|1276070_1276670_-\|head,protease	HK97 family phage prohead protease	Q8SBH9	Shigella_phage	1.0e-90	82.5
WP_023313057.1\|1276662_1277889_-\|portal	phage portal protein	Q8SBI0	Shigella_phage	4.2e-208	85.0
WP_032737698.1\|1278036_1279788_-\|terminase	terminase large subunit	A0A1P8DTK0	Proteus_phage	1.8e-252	72.2
WP_001119413.1\|1279791_1280289_-\|terminase	phage terminase small subunit P27 family	K7PHI2	Enterobacteria_phage	7.4e-63	71.3
WP_117247952.1\|1280446_1280797_-	HNH endonuclease	A0A1B5FP94	Escherichia_phage	7.1e-52	80.9
WP_117247954.1\|1280799_1281120_-	hypothetical protein	NA	NA	NA	NA
WP_117247953.1\|1281185_1281431_-	DUF2560 family protein	A0A286N2R1	Klebsiella_phage	4.2e-19	64.2
WP_114475993.1\|1281519_1281711_-	hypothetical protein	A0A286SGR9	Klebsiella_phage	2.4e-22	94.5
WP_032448071.1\|1281661_1281937_-	hypothetical protein	G8C7W1	Escherichia_phage	6.0e-06	37.1
WP_101415860.1\|1281939_1282569_-	glycoside hydrolase family 19 protein	F1C591	Cronobacter_phage	2.1e-86	74.4
WP_101983094.1\|1282568_1282850_-\|holin	phage holin family protein	K7PKN9	Enterobacterial_phage	4.1e-18	46.2
WP_001294159.1\|1282836_1283223_-	membrane protein	A0A192Y8P2	Salmonella_phage	1.6e-57	90.6
WP_152659726.1\|1283475_1284246_+	hypothetical protein	NA	NA	NA	NA
WP_131091278.1\|1284283_1284649_-	DUF1133 family protein	K7PGW2	Enterobacterial_phage	4.3e-52	81.7
WP_152659727.1\|1284667_1285648_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	3.2e-134	66.9
WP_032737684.1\|1285660_1286038_-	RusA family crossover junction endodeoxyribonuclease	A0A1C9IIA0	Salmonella_phage	1.8e-48	73.6
WP_061363443.1\|1286047_1286857_-	Dam family site-specific DNA-(adenine-N6)-methyltransferase	A0A1C9II58	Salmonella_phage	1.6e-110	69.7
WP_060618150.1\|1286853_1287768_-	transcriptional regulator	H2DE83	Erwinia_phage	2.4e-30	57.3
WP_071557781.1\|1287724_1287937_-	DUF4222 domain-containing protein	S5M7S5	Escherichia_phage	6.4e-16	70.9
WP_004213338.1\|1288174_1288636_-	hypothetical protein	K7PJS5	Enterobacterial_phage	1.7e-69	88.2
WP_024176406.1\|1288661_1288871_-	cell division protein	NA	NA	NA	NA
WP_019705289.1\|1288965_1289610_+	helix-turn-helix domain-containing protein	A0A1I9KG86	Aeromonas_phage	8.2e-38	40.7
WP_048287748.1\|1289881_1290799_+	hypothetical protein	A0A1W6JP69	Morganella_phage	5.2e-46	36.9
WP_040181807.1\|1290888_1291188_+	hypothetical protein	NA	NA	NA	NA
WP_152659728.1\|1291187_1291973_+	hypothetical protein	A4JX52	Burkholderia_virus	2.6e-62	51.0
WP_152659729.1\|1292100_1292634_+	hypothetical protein	E7C9P6	Salmonella_phage	1.8e-30	51.0
WP_075647491.1\|1292630_1292888_+	DUF4752 family protein	T1S9K2	Salmonella_phage	5.6e-30	74.1
WP_152659730.1\|1292884_1293637_+	hypothetical protein	M1FN76	Enterobacteria_phage	4.9e-127	84.8
WP_152659731.1\|1293647_1294166_+	DUF550 domain-containing protein	S4TSR6	Salmonella_phage	9.8e-42	81.6
WP_077274609.1\|1294173_1294359_+	hypothetical protein	G3CFG7	Escherichia_phage	4.0e-14	65.5
WP_080870864.1\|1294470_1295337_-	hypothetical protein	NA	NA	NA	NA
WP_152659732.1\|1295374_1296544_-\|integrase	tyrosine-type recombinase/integrase	A0A2R2Z2Y0	Escherichia_phage	9.5e-202	85.8
WP_048985683.1\|1297690_1298224_-	hypothetical protein	NA	NA	NA	NA
1296739:1296762	attR	NA	NA	NA	NA
WP_129718279.1\|1298220_1298670_-	hypothetical protein	NA	NA	NA	NA
WP_071838925.1\|1299458_1299857_-	hypothetical protein	NA	NA	NA	NA
WP_136398120.1\|1300364_1300922_-	hypothetical protein	NA	NA	NA	NA
WP_049107563.1\|1303680_1304163_-	hypothetical protein	NA	NA	NA	NA
WP_086472102.1\|1304405_1305143_-	hypothetical protein	NA	NA	NA	NA
WP_023317120.1\|1305175_1305520_-	hypothetical protein	NA	NA	NA	NA
WP_023317121.1\|1305513_1306017_-	DUF4123 domain-containing protein	A4PE24	Ralstonia_virus	5.1e-19	40.7
WP_083566682.1\|1306013_1306766_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_048269345.1\|1306793_1307537_-	hypothetical protein	NA	NA	NA	NA
WP_048269696.1\|1307577_1308123_-	hypothetical protein	NA	NA	NA	NA
WP_074185282.1\|1308191_1308788_-	hypothetical protein	NA	NA	NA	NA
WP_053067564.1\|1309510_1310065_-	DUF4123 domain-containing protein	NA	NA	NA	NA
WP_083565429.1\|1310066_1312382_-	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_083565430.1\|1312386_1312911_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_083565433.1\|1312944_1314027_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_083565435.1\|1313990_1315760_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA

DBSCAN-SWA_4

4507636 : 4517099

Dickeya_phage(16.67%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002896440.1\|4507636_4508752_+	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	1.3e-06	52.7
WP_004150848.1\|4508748_4510689_+	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	1.9e-37	40.5
WP_002896516.1\|4510765_4510987_-	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	1.3e-16	61.2
WP_002896520.1\|4511312_4511630_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	2.0e-13	45.7
WP_002896522.1\|4511660_4513940_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.6e-165	42.0
WP_001040187.1\|4514059_4514278_-	translation initiation factor IF-1	NA	NA	NA	NA
WP_002898014.1\|4514631_4515333_-\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_004179158.1\|4515377_4517099_-	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	A0A2R8FG22	Brazilian_cedratvirus	1.5e-14	34.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP035194

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection