CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NZ_CP043831	Bacillus sp. BS98 plasmid unnamed1	0 crisprs	csa3,cas14j	0	0	2
NZ_CP043833	Bacillus sp. BS98 plasmid unnamed3	0 crisprs	NA	0	0	0
NZ_CP043830	Bacillus sp. BS98 chromosome, complete genome	3 crisprs	cas3,csa3,WYL,RT,DinG,c2c9_V-U4,DEDDh	6	3	4
NZ_CP043832	Bacillus sp. BS98 plasmid unnamed2	0 crisprs	cas14j,csa3,cas14k	0	0	0
NZ_CP043834	Bacillus sp. BS98 plasmid unnamed4	0 crisprs	cas14j	0	0	1

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

54024 : 186983

107

Bacillus_phage(41.38%)

integrase,protease,bacteriocin,transposase

attL 133036:133053|attR 182137:182154

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149890091.1\|54024_55146_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	S6AND0	Bacillus_phage	4.6e-161	76.1
WP_053446171.1\|56170_56962_+	hypothetical protein	NA	NA	NA	NA
WP_000648288.1\|58751_59030_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A2I7SC16	Paenibacillus_phage	1.6e-14	67.2
WP_149890092.1\|59238_59769_-	SMI1/KNR4 family protein	NA	NA	NA	NA
WP_149890093.1\|59837_62270_-	DUF5011 domain-containing protein	NA	NA	NA	NA
WP_149890174.1\|62846_63125_+	hypothetical protein	NA	NA	NA	NA
WP_000958319.1\|63232_63865_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000755964.1\|64083_64251_-	hypothetical protein	NA	NA	NA	NA
WP_149890094.1\|64250_65345_-	tetratricopeptide repeat protein	A0A2H4J8G3	uncultured_Caudovirales_phage	7.8e-73	41.7
WP_149890095.1\|66144_66534_+	hypothetical protein	NA	NA	NA	NA
WP_149890096.1\|67224_68160_+	DUF3994 domain-containing protein	NA	NA	NA	NA
WP_149890097.1\|68470_68830_-	hypothetical protein	NA	NA	NA	NA
WP_098190586.1\|72252_72795_+	hemolysin BL-binding protein	NA	NA	NA	NA
WP_149890098.1\|72809_73355_+	hypothetical protein	NA	NA	NA	NA
WP_149890099.1\|73420_73744_+	hypothetical protein	NA	NA	NA	NA
WP_149890100.1\|74140_74395_-	hypothetical protein	NA	NA	NA	NA
WP_172624237.1\|74639_75386_+	M15 family metallopeptidase	NA	NA	NA	NA
WP_149890102.1\|75791_76427_+	hypothetical protein	NA	NA	NA	NA
WP_149890103.1\|76787_77003_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_149890104.1\|77243_77834_+	DUF5512 family protein	NA	NA	NA	NA
WP_172624230.1\|78419_79394_-	hypothetical protein	NA	NA	NA	NA
WP_000196658.1\|79584_79884_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_149890106.1\|80161_81355_-	putative DNA binding domain-containing protein	NA	NA	NA	NA
WP_149890108.1\|82397_82739_-	YolD-like family protein	U3PG23	Staphylococcus_phage	2.7e-08	39.5
WP_172624231.1\|84413_85925_+\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_149890110.1\|86383_87145_-	hypothetical protein	NA	NA	NA	NA
WP_149890111.1\|87416_87596_-	hypothetical protein	NA	NA	NA	NA
WP_149890112.1\|87684_88305_-	HAD-IA family hydrolase	NA	NA	NA	NA
WP_149890113.1\|88856_89153_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_149890175.1\|89220_89607_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A0N9SIX5	Staphylococcus_phage	7.6e-15	44.3
WP_149890114.1\|89650_90226_-	hypothetical protein	NA	NA	NA	NA
WP_149890115.1\|90880_92680_-	hypothetical protein	A0A1I9SA50	Rhodococcus_phage	4.7e-14	42.7
WP_001025758.1\|93023_93242_-	alpha/beta-type small acid-soluble spore protein	A0A1P8CX76	Bacillus_phage	9.2e-18	65.2
WP_149890116.1\|93583_93880_-	hypothetical protein	NA	NA	NA	NA
WP_149890117.1\|94513_95686_-\|integrase	tyrosine-type recombinase/integrase	A0A142F1N9	Bacillus_phage	6.8e-06	23.1
WP_098009472.1\|96089_97091_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_098009470.1\|98531_99863_-	nucleotide sugar dehydrogenase	M1H3J6	Paramecium_bursaria_Chlorella_virus	4.8e-40	32.1
WP_098009468.1\|100193_100853_-	citrate/2-methylcitrate synthase	NA	NA	NA	NA
WP_098009493.1\|101126_101741_-	hypothetical protein	NA	NA	NA	NA
WP_149890176.1\|101956_103108_-	radical SAM protein	NA	NA	NA	NA
WP_080001321.1\|103118_103529_-	NUDIX pyrophosphatase	NA	NA	NA	NA
WP_098009489.1\|103563_104640_-	aminotransferase class V-fold PLP-dependent enzyme	A0A2K9L0G1	Tupanvirus	1.1e-31	29.7
WP_097825628.1\|104707_105772_-	hypothetical protein	NA	NA	NA	NA
WP_085451225.1\|105934_106135_-	alpha/beta hydrolase fold domain-containing protein	NA	NA	NA	NA
WP_097825630.1\|106405_106627_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001060875.1\|107387_108521_+	nucleotidyltransferase family protein	NA	NA	NA	NA
WP_001005136.1\|108595_109420_+	HAD-IIB family hydrolase	NA	NA	NA	NA
WP_000401834.1\|109633_110821_-	acyl-CoA/acyl-ACP dehydrogenase	NA	NA	NA	NA
WP_002040144.1\|110833_111043_-	hypothetical protein	NA	NA	NA	NA
WP_098009466.1\|111059_112295_-	decarboxylase	NA	NA	NA	NA
WP_098009464.1\|112295_113771_-	acyl--CoA ligase	A0A2K9KZV5	Tupanvirus	1.4e-37	26.1
WP_097825632.1\|114638_114953_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_002046373.1\|114949_115471_+\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	5.6e-37	48.2
WP_097825633.1\|115700_117434_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.9e-37	27.3
WP_098009462.1\|117434_119237_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.2e-32	26.9
WP_149890118.1\|120597_122214_-	(2,3-dihydroxybenzoyl)adenylate synthase	A0A2K9L3I8	Tupanvirus	4.8e-10	24.0
WP_098010153.1\|122226_123426_-	isochorismate synthase DhbC	NA	NA	NA	NA
WP_000364391.1\|123452_124229_-	2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	3.4e-14	28.6
WP_085451217.1\|124550_125267_-	4'-phosphopantetheinyl transferase superfamily protein	NA	NA	NA	NA
WP_170952452.1\|126040_126523_-	hypothetical protein	A0A2K9KZV5	Tupanvirus	8.9e-13	29.8
WP_098010155.1\|126713_127412_-	thioesterase	NA	NA	NA	NA
WP_098010157.1\|128685_129687_-	hypothetical protein	NA	NA	NA	NA
WP_098010159.1\|129691_130240_-	hypothetical protein	NA	NA	NA	NA
WP_000174708.1\|130459_131347_-	isochorismatase family protein	NA	NA	NA	NA
WP_098010161.1\|131375_131702_-	hypothetical protein	NA	NA	NA	NA
WP_097825640.1\|131697_136170_-	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	1.9e-85	26.7
133036:133053	attL	NA	NA	NA	NA
WP_098010163.1\|136808_138035_-	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_098010165.1\|138066_139149_-	threonine aldolase	NA	NA	NA	NA
WP_098010167.1\|139243_140503_-	MFS transporter	NA	NA	NA	NA
WP_098010169.1\|140860_141280_+	transcriptional regulator	NA	NA	NA	NA
WP_000435034.1\|142884_143067_-	hypothetical protein	NA	NA	NA	NA
WP_098010173.1\|143392_144070_-	response regulator transcription factor	NA	NA	NA	NA
WP_000892394.1\|144619_144823_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000247165.1\|144822_145122_+	hypothetical protein	NA	NA	NA	NA
WP_098010049.1\|145254_146685_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_098010051.1\|147001_147760_-	DUF975 family protein	NA	NA	NA	NA
WP_144467341.1\|148319_149441_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	S6AND0	Bacillus_phage	1.8e-165	78.8
WP_053446075.1\|149943_150456_-	hypothetical protein	NA	NA	NA	NA
WP_141438357.1\|150571_150904_-	hypothetical protein	NA	NA	NA	NA
WP_098009650.1\|151098_152328_-	DUF3994 domain-containing protein	NA	NA	NA	NA
WP_098009652.1\|153097_153718_+	DUF2278 family protein	NA	NA	NA	NA
WP_098009654.1\|154320_154536_-	aspartyl-phosphate phosphatase Spo0E family protein	NA	NA	NA	NA
WP_149890119.1\|155229_155829_-	hypothetical protein	NA	NA	NA	NA
WP_149890120.1\|157217_157628_+	hypothetical protein	NA	NA	NA	NA
WP_149890121.1\|158101_158587_-	hypothetical protein	NA	NA	NA	NA
WP_149890122.1\|158645_159128_-	tungsten formylmethanofuran dehydrogenase	NA	NA	NA	NA
WP_000717614.1\|159638_159941_-	hypothetical protein	NA	NA	NA	NA
WP_000768760.1\|160698_161010_-	hypothetical protein	NA	NA	NA	NA
WP_149890123.1\|161166_161709_-\|integrase	tyrosine-type recombinase/integrase	W8CYP1	Bacillus_phage	2.6e-85	88.3
WP_149890124.1\|161708_162173_-	ArpU family transcriptional regulator	D2XR57	Bacillus_phage	1.6e-72	92.2
WP_149890125.1\|162415_164593_-	amidase domain-containing protein	A0A0C5AEJ0	Paenibacillus_phage	1.6e-05	27.5
WP_053446363.1\|164909_165101_-	DUF3954 domain-containing protein	D2XR48	Bacillus_phage	1.3e-20	77.8
WP_149890126.1\|165177_165474_-	cell division protein SepF	D2XR47	Bacillus_phage	1.4e-40	88.0
WP_149890127.1\|167716_168469_-	hypothetical protein	NA	NA	NA	NA
WP_001043917.1\|168767_169040_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	2.2e-24	67.8
WP_000132662.1\|170966_171131_+	hypothetical protein	A0A288WGN0	Bacillus_phage	1.5e-09	55.6
WP_149890128.1\|172877_174068_-	MFS transporter	NA	NA	NA	NA
WP_149890129.1\|174419_175007_+	TetR/AcrR family transcriptional regulator C-terminal ligand-binding domain-containing protein	NA	NA	NA	NA
WP_098010103.1\|175375_176389_-	hypothetical protein	NA	NA	NA	NA
WP_149890130.1\|177051_177531_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000087405.1\|177719_177914_-	hypothetical protein	NA	NA	NA	NA
WP_000961802.1\|178007_178349_-	DUF4257 domain-containing protein	NA	NA	NA	NA
WP_000939326.1\|178930_179119_-	hypothetical protein	NA	NA	NA	NA
WP_149890131.1\|180176_182306_-	adhesin	NA	NA	NA	NA
182137:182154	attR	NA	NA	NA	NA
WP_149890132.1\|184128_185100_-	sigma-70 family RNA polymerase sigma factor	A0A2I7SAT0	Vibrio_phage	9.5e-14	25.5
WP_000599429.1\|185260_186379_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	D2XQ03	Bacillus_virus	1.5e-172	79.6
WP_000878680.1\|186341_186983_-\|transposase	IS607 family transposase	Q331Z3	Clostridium_botulinum_C_phage	7.8e-57	55.2

DBSCAN-SWA_2

261999 : 269968

Bacillus_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_149890164.1\|261999_262320_+	hypothetical protein	A0A0S2GLK1	Bacillus_phage	3.3e-32	67.0
WP_149890165.1\|262330_263497_+	DUF87 domain-containing protein	A0A0S2GLG9	Bacillus_phage	1.2e-180	79.6
WP_033658465.1\|263537_264095_+	replication-relaxation family protein	W8CZ47	Bacillus_phage	3.4e-80	75.1
WP_144467401.1\|264732_265380_+	lysozyme family protein	A0A223LKM8	Bacillus_phage	1.0e-16	33.7
WP_172624238.1\|265676_267122_-	HAMP domain-containing protein	W8CYF6	Bacillus_phage	2.4e-21	28.0
WP_149890166.1\|267168_267834_-	response regulator	W8CYM9	Bacillus_phage	6.7e-35	35.6
WP_172624236.1\|267997_268174_+	hypothetical protein	NA	NA	NA	NA
WP_149890167.1\|268774_269968_+	trypsin-like peptidase domain-containing protein	A0A1B1IT49	uncultured_Mediterranean_phage	1.5e-24	31.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP043830

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP043830_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043830_1

3217571-3217671

Orphan

Consensus_repeat	Method
TCTCTCTGCTCTCTTCTCTTTTC	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of NZ_CP043830_1

>merge|NZ_CP043830|1|3217571-3217671|CRISPRCasFinder
TTTCGCTGCTTTTCTTTCTCTTCTTTTTCTCTCTGCTCTCTTCTCTTTTCCTGCTCTTCCTGCTCTTCCTGTTCTTTCTCTTTCTGCTCTCTTCTCTTTTC

>NZ_CP043830|1|1|3217571-3217671|CRISPRCasFinder
TTTCGCTGCTTTTCTTTCTCTTC	TTTTTCTCTCTGCTCTCTTCTCTTTTCCTGCTCTTCCTGCTCTTCCTGTTCTTTC
TCTTTCTGCTCTCTTCTCTTTTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043830.1\|WP_149889897.1\|3208492_3211843_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|200584
NZ_CP043830.1\|WP_149889898.1\|3221737_3222499_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP043830.1\|WP_001072967.1\|3204735_3205059_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|334619
NZ_CP043830.1\|WP_000801034.1\|3219270_3219750_-\|effector-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|379638
NZ_CP043830.1\|WP_000742460.1\|3226072_3226846_-\|BcII-family-subclass-B1-metallo-beta-lactamase	unknown	unknown	gnl\|CDD\|293862
NZ_CP043830.1\|WP_000429488.1\|3223238_3223559_-\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609
NZ_CP043830.1\|WP_000891987.1\|3222821_3223163_-\|DUF1048-domain-containing-protein	unknown	unknown	gnl\|CDD\|368835
NZ_CP043830.1\|WP_000755055.1\|3219859_3220822_+\|HTH-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NZ_CP043830.1\|WP_000739854.1\|3226982_3227720_-\|glycoside-hydrolase-family-25-protein	unknown	unknown	gnl\|CDD\|119375
NZ_CP043830.1\|WP_002093524.1\|3213374_3214097_-\|RNA-polymerase-sigma-factor-SigI	unknown	unknown	gnl\|CDD\|236233
NZ_CP043830.1\|WP_149889896.1\|3206478_3207681_+\|ankyrin-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|293786
NZ_CP043830.1\|WP_000837814.1\|3220987_3221737_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224596
NZ_CP043830.1\|WP_000660069.1\|3207965_3208241_-\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238042
NZ_CP043830.1\|WP_149889895.1\|3205320_3206121_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	unknown
NZ_CP043830.1\|WP_000140994.1\|3214680_3215442_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133016
NZ_CP043830.1\|WP_002093521.1\|3224045_3225332_-\|hydroxylamine-reductase	unknown	unknown	gnl\|CDD\|183427
NZ_CP043830.1\|WP_000265911.1\|3216807_3217029_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043830.1\|WP_001028133.1\|3227754_3228036_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|212142
NZ_CP043830.1\|WP_016091222.1\|3212047_3213385_-\|anti-sigma-factor-domain-containing-protein	unknown	unknown	gnl\|CDD\|237171
NZ_CP043830.1\|WP_000254117.1\|3215540_3216173_-\|LysE-family-translocator	unknown	unknown	gnl\|CDD\|224199

Protein	Function_ID	Function_description	E-value
NZ_CP043830.1\|WP_149889897.1\|3208492_3211843_-\|glycosyltransferase	gnl\|CDD\|200584	cd10962, CE4_GT2-like, Catalytic NodB homology domain of uncharacterized bacterial glycosyl transferase, group 2-like family proteins. This family includes many uncharacterized bacterial proteins containing an N-terminal GH18 (glycosyl hydrolase, family 18) domain, a middle NodB-like homology domain, and a C-terminal GT2-like (glycosyl transferase group 2) domain. Although their biological function is unknown, members in this family contain a middle NodB homology domain that is similar to the catalytic domain of Streptococcus pneumoniae polysaccharide deacetylase PgdA (SpPgdA), an extracellular metal-dependent polysaccharide deacetylase with de-N-acetylase activity toward a hexamer of chitooligosaccharide N-acetylglucosamine, but not shorter chitooligosaccharides or a synthetic peptidoglycan tetrasaccharide. Like SpPgdA, this family is a member of the carbohydrate esterase 4 (CE4) superfamily. The presence of three domains suggests that members of this family may be multifunctional.	4.77328e-110
NZ_CP043830.1\|WP_149889898.1\|3221737_3222499_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	8.10769e-92
NZ_CP043830.1\|WP_001072967.1\|3204735_3205059_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|334619	pfam01638, HxlR, HxlR-like helix-turn-helix. HxlR, a member of this family, is a DNA-binding protein that acts as a positive regulator of the formaldehyde-inducible hxlAB operon in Bacillus subtilis.	8.01301e-42
NZ_CP043830.1\|WP_000801034.1\|3219270_3219750_-\|effector-binding-domain-containing-protein	gnl\|CDD\|379638	pfam14526, Cass2, Integron-associated effector binding protein. This family contains Cass2 from Vibrio cholerae, an integron-associated protein that has been shown to bind cationic drug compounds with submicromolar affinity. Cass2 has been proposed to be representative of a larger family of independent effector-binding proteins associated with lateral gene transfer within Vibrio and other closely-related species.	8.24502e-31
NZ_CP043830.1\|WP_000742460.1\|3226072_3226846_-\|BcII-family-subclass-B1-metallo-beta-lactamase	gnl\|CDD\|293862	cd16304, BcII-like_MBL-B1, Bacillus cereus Beta-lactamase 2 and related metallo-beta-lactamases, subclass B1; MBL-fold metallo-hydrolase domain. Bacillus cereus Beta-lactamase 2, also called BcII. MBLs (class B of the Ambler beta-lactamase classification) have been divided into three subclasses B1, B2 and B3, based on sequence/structural relationships and substrates, with the B1 and B2 MBLs being most closely related to each other. BcII is a chromosome-encoded B1 MBL. B1 enzymes are most active with two zinc ions bound in the active site, and have a broad-spectrum substrate profile.	7.47413e-120
NZ_CP043830.1\|WP_000429488.1\|3223238_3223559_-\|PadR-family-transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	1.60634e-24
NZ_CP043830.1\|WP_000891987.1\|3222821_3223163_-\|DUF1048-domain-containing-protein	gnl\|CDD\|368835	pfam06304, DUF1048, Protein of unknown function (DUF1048). This family consists of several hypothetical bacterial proteins of unknown function.	1.57041e-46
NZ_CP043830.1\|WP_000755055.1\|3219859_3220822_+\|HTH-domain-containing-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	6.1713e-18
NZ_CP043830.1\|WP_000739854.1\|3226982_3227720_-\|glycoside-hydrolase-family-25-protein	gnl\|CDD\|119375	cd06413, GH25_muramidase_1, Uncharacterized bacterial muramidase containing a glycosyl hydrolase family 25 (GH25) catalytic domain. Endo-N-acetylmuramidases are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues.	6.30321e-104
NZ_CP043830.1\|WP_002093524.1\|3213374_3214097_-\|RNA-polymerase-sigma-factor-SigI	gnl\|CDD\|236233	PRK08311, PRK08311, RNA polymerase sigma factor SigI.	4.3074e-101
NZ_CP043830.1\|WP_149889896.1\|3206478_3207681_+\|ankyrin-repeat-domain-containing-protein	gnl\|CDD\|293786	sd00045, ANK, ankyrin repeats. Ankyrin repeats are one of the most abundant repeat motifs, and generally function as scaffolds for protein-protein interactions in processes including cell cycle, transcriptional regulation, signal transduction, vesicular trafficking, and inflammatory response. Although predominantly found in eukaryotic proteins, they are also found in some bacterial and viral proteins. Less is known of their physiological roles in prokaryotes. Some bacterial ANK proteins play key roles in microbial pathogenesis by mimicking or manipulating host function(s). The pathogen Providencia alcalifaciens N-formyltransferase ankyrin repeats function in small molecule binding and allosteric control. Ankyrin-repeat proteins have been associated with a number of human diseases.	7.72078e-23
NZ_CP043830.1\|WP_000837814.1\|3220987_3221737_-\|ABC-transporter-permease	gnl\|CDD\|224596	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	1.14157e-11
NZ_CP043830.1\|WP_000660069.1\|3207965_3208241_-\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	4.97762e-11
NZ_CP043830.1\|WP_001028133.1\|3227754_3228036_-\|hypothetical-protein	gnl\|CDD\|212142	cd11535, NTP-PPase_SsMazG, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Sulfolobus solfataricus (Ss) and its homologs from archaea and bacteria. This family includes a MazG-like protein from Sulfolobus solfataricus (SsMazG) and its homologs from archaea and bacteria. Although its biological roles remain still unclear, SsMazG shows significant sequence similarity to the NTP-PPase MazG proteins. However, unlike typical tandem-domain MazG proteins, SsMazG contains a single MazG-like domain. It is predicted that SsMazG might participate in house-cleaning by preventing incorporation of the oxidation product 2-oxo-(d)ATP (iso-dGTP), a mutagenic derivative of ATP, into DNA.	8.17421e-12
NZ_CP043830.1\|WP_000140994.1\|3214680_3215442_-\|glycosyltransferase	gnl\|CDD\|133016	cd02525, Succinoglycan_BP_ExoA, ExoA is involved in the biosynthesis of succinoglycan. Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.	5.33452e-31
NZ_CP043830.1\|WP_002093521.1\|3224045_3225332_-\|hydroxylamine-reductase	gnl\|CDD\|183427	PRK12310, PRK12310, hydroxylamine reductase; Provisional.	0
NZ_CP043830.1\|WP_000254117.1\|3215540_3216173_-\|LysE-family-translocator	gnl\|CDD\|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	2.00251e-47
NZ_CP043830.1\|WP_016091222.1\|3212047_3213385_-\|anti-sigma-factor-domain-containing-protein	gnl\|CDD\|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	1.68715e-14

>NZ_CP043830.1|WP_000265911.1|3216807_3217029_+|hypothetical-protein
MWKRIKNYRLSLKDLKFMLWLFSITCFIYSYNFITGLAFDHKFQVYYLGGAIATYAAFIDTKNRIKNKIYKTA
>NZ_CP043830.1|WP_000254117.1|3215540_3216173_-|LysE-family-translocator
MVSLSTLVAFAIVSLSMVCSPGPNMIYLISRSVTQGRMAGFISLLGIMLGFVIYIIATMFGLTVLFVAVPAVYEAVKWAGAAYLLWLAWNSIKPGATSIMEPRMISNEPPRKLFLMGLMTNLLNPKIAILYVSLLPQFEDPEKGSLLFQGAVLGLTQITVSFIVNLVIVCTASKIAKWFGTRPTWLRVQRWLMASVLTGLAVRLAFERRQ
>NZ_CP043830.1|WP_000140994.1|3214680_3215442_-|glycosyltransferase
MTETNEFSGVNLKKDVKFSIIIPAHNEEKYIRKCLDSIAKASEAYKEQTEVIVVLNRCTDKTEEIAKSYNCVTLKNNDKNLSKIRNAGAKIANGEIIVTIDADTIMTESMLSNVDKYLTSGKYIGGGVNGKFERISLGIFLSAMLIIIPLLFKYGAISVGIFWCYRKDFMAINGFNENMLMAEDADFAKRLKEWGKKNNKKFGTIKNGMITSCRRFDTYGDWTLLKNPKVILAYLKGNDRKYADKTYYDNQER
>NZ_CP043830.1|WP_002093524.1|3213374_3214097_-|RNA-polymerase-sigma-factor-SigI
MLSLVMKILRKPKIEDIVCNIQNNEADKEAFIVQYQPFIRKSISSVCRRYITEQDDEYSIGLFAFNEAIEQYSYTKGKSFLAFADLLIKRDVIDYIRKESKHNFVFLKEDEQEEMLEMQVSLTEYMKEMENSNRKEEILHFQSVLAEFKITFSELAKESPKHRDTREHLIEIVKIIIKEEEMMEELFRKKKLPLKHIEPRVRVSRKTLERHRKYIIAMCIIFANNYTYILDYIRGEKHDE
>NZ_CP043830.1|WP_016091222.1|3212047_3213385_-|anti-sigma-factor-domain-containing-protein
MMNKGIVMDIKKHSVVVLTPNGEFITCKRKGDSCMIGEEISFDEQEQKASHFSIPSFLKPASILVACFLFAVLFFYNQPEEKVFAYVSVDINPSLEVSVTRDFRVIDLQACNDDGRRILKELKQWENKQLQEVIRTIIKQSQEDKYLTNDKQVMLTAVAKDKALEPQLEKAMKELKKEYELKHITVEYQSSTMQVRENARKAGIGTGVYIKQENEKNKSLTPPAMPSNPVENEEEVQSQPESSPNASLDLSPVDEKKYEKQEQKEQKKTEEQPSKQIKENNGRGSQQENRGNQQENNSRESQQGNNGNQQGNNGRGSQQGNNGNGQGNNGRGSQQGNNGNGQGNNGRGSQQGNNGNEQGNNGRGSQQGDNGNEQGNNGRGSQQENNGNQQGNNGRNPQQGNNGNQQGNNGRGSQKENDGNEKGNNSRGSQQENRGHQQGNEKKNQ
>NZ_CP043830.1|WP_149889897.1|3208492_3211843_-|glycosyltransferase
MEKNIQQEKDKEKPVFYDPKGRRNIAFIWFLCISIVSVSVVFYFFFQSIFSTPEIPNMNTAVQQDTKLVPINQKLSDQQLKKEEFKLNTETKDNKNLVNSPKDSKQPKEVYGFYVNWDENSTASLKENIDSLTTLVPEWYHLKADLTIRSEIKPEIVKLAEKNQVKIMPLLTNYTEEASGPDSGLIHKLLNSSNDVKTKFINDLVSQVKKNQFSGINIDFEAVPESDRENLTNFMKELTTEFHEHDLLATQDVPANDKAFDYSALAKIIDRMIVMMYDEHYGAGEPGPIASNKWFQHTLKELNIPSNKLIVAFGNYGYDWEVNSKVAAKSLTFSEVMAMAHDSNMKIQWDKMSGNPYFRYKTGEKEHTAWFLDGVTLYNQVKIAMDNNAKGFALWRLGAEDPTIWKVLKNPIEVQKNPNVLHKINSLDEVNYSGQGEMLQIENERKNGMRDFKVGKDGYLTDEVYHSLPSAYEVQRYGKPNGKQVVLTFDDGPDPKYTPEILDILKENKINAAFFVLGENAQLNTNIVKRIYDEGHEIGNHTFKHPNIADTSLLRTKVELNTTQRLIQEVTGHSTVLFRPPYEADANPDSSNEILPILRAQNMNYTMVGEKVDPEDWATPSTNELVRRALNPIYKGEGNIILLHDAGGNRTHTVEALPIIIKDLKKHGYSFVTISDLMNKERDEIMPPVSSEGKQYLLYNKAVFSGAGYAKHILTTIFYIAIGLGIFRFLFLIYFAYKQKKTVSARLFTNSSYQPFVTVVIAAYNEEKVIAKTIRSILDSDYREFEVIVVDDGSKDGTSKVMEETFYKHPKVRLIQKENGGKSSAMNLGFQQSRGEIIVTLDADTIIAQDAISLMIRHFEDHNVAAVSGNVKVGNRRNLLTTWQHVEYITGFNLERRAFDELNCITVVPGAIGAWRKKNVVESGYLSEDTLAEDTDLTITFLRQGHRIVYEEKAYAFTESPEDVKSLIKQRYRWSYGTLQCLWKHRKALFHSKHKALGFIALPNMWLFQYVLQFIAPLADILMIMGLFGSNPLKVLGFYLVFFVIDLLASLFAFKLEKENPKPLAWLILQRFIYRQFMTYVVIKSIFSSIRGVAVGWNKLKRMGSVKHSTEHKEAS
>NZ_CP043830.1|WP_000660069.1|3207965_3208241_-|winged-helix-turn-helix-transcriptional-regulator
MKEKKEMYVEIAEVLKVLAHPVRLSLVKIMLAKGATNVTTMYGNLQMPQSTISQHLSKLKAAKIVTGTRKGLEIYYEVTDNRTKSILACLV
>NZ_CP043830.1|WP_149889896.1|3206478_3207681_+|ankyrin-repeat-domain-containing-protein
MKNQYIATLVEIVLKHIPNAAEKSILFAFYNGVVTTYSYFHYESMKVFEHGSEGLPSNEIMDNIQRVRHTGESNWTAFVLTVKTNGLYEVDYYDDLNPTLECSSALLLLAYSHYHIEPTSDFGKSQLQSAIKAESFKKTLNYACMRNDIETVKEKLVNIKLSTLNKKGPDRKTPLHIACLNGNIEIVTLLVEAGADLKIKYHGETPFALACGKGNVEIIKYLISKGENANDIMVGKVTPLHLISSSGNQEIVQYILERITNINAVTNRKRSALHYAVEDNNLEAAKVLIDNGIDMELLEEYKRGALSLACGRNKPEMAALLLENGANIHSTGQGKITPLHSACEQGFIEVVRVLLQHQPNLHEKATLYSMPKNEKLKETPIETAERLGYDEIVELLSSKL
>NZ_CP043830.1|WP_149889895.1|3205320_3206121_-|ABC-transporter-ATP-binding-protein
MELFDYYKRKGKFKLLIGTGIFILALCAVYDDWGHVNWGQIIFFVIASSIFFGIGFWQLRKGKLIQKNTIKSNATFWDVDTFVVLELPKRNKQFGLYHPDGGYIAGTKIVSSNILFSVIPFLHNKDVYGLETSSGEIIAYFHTEVDGYDWVTYGSNYNQIGMFKEKMIQGFTMIRGTLMTDKATKLSDVEVEFDFIQSTLRTIEGRTLAIGKQGYMLIEWSERFMGLNVPTITLGSNASNNEKILGLGVLLYSLRTIEIRKNRASV
>NZ_CP043830.1|WP_001072967.1|3204735_3205059_+|helix-turn-helix-transcriptional-regulator
MNQNDDCPIATTLDVIGGKWKVYILCVLMDGKMRTNEIKREIPNLTQKVLTQQLRQLEADGIIHRTVYQEVPPKVEYTISEHGKSLMHIMNELFEWGKDHQMKRLND
>NZ_CP043830.1|WP_000801034.1|3219270_3219750_-|effector-binding-domain-containing-protein
MKNYTIEEKDSFIVLGIGTEIKSEYTDFAGINKEKEDFWSAVKEDGRLDTLKALATNEYIFSVSEAVNNKMMYYAGVMTEAQIEEESRVIQFPKGEYVVVKGEGKTAEELSNKLTGIAFGQALPEAKDFAYVGGPNTTVEMGQRNGLLFGEMWIPVVRK
>NZ_CP043830.1|WP_000755055.1|3219859_3220822_+|HTH-domain-containing-protein
MKKVERINTIMRYINNRSHFTISEIIREFNISRSTAIRDIREIEAMGMPLVAEVGRTGGYFVMHNSILPVVRFTDNEVKALFIAFMATRNQQLPYLKSRQSLAEKLLGLISETQQDDLVLLNQLLLFEGTNPHNPDLLELSDLPHPMLEKLIQLLLLDNHLLITIKEEKEIKSYPIYLLHLYQEKSHWIIEGFDLKEEKKIMFPVDDLTNIEPYTTKKRLNKKKILEKLSKKDEIINLVLELGPKAIAQFKKYHPLKGSISYTNPYQSTAILKTFINVNNPDEVTEITNWLLFLGKDIKIREIPDEVLADLQKRVCLYIP
>NZ_CP043830.1|WP_000837814.1|3220987_3221737_-|ABC-transporter-permease
MKSKTGVLLGRLMRNIMRSPDTIITVAITPIMMMLLFVYVFGGAIKTGTENYVNYLLPGILLMAIASGVAYTSVRLFTDVKSGLMARFITMPIKRSSILWAHVLTSLVANVLTIVVVILVALLMGFRSSANILDWLAVAGILGMFTLALTWLAIIPGLKAKSMEGATAYSYPLVFLPFISSAFVPTETMPKIVRAFAENQPVTSIVNAIRALLYEGTVGNDIWIALAWCVGIMVIAYFFASKAFKRQLG
>NZ_CP043830.1|WP_149889898.1|3221737_3222499_-|ATP-binding-cassette-domain-containing-protein
MSNAAISIKGLKKSFKDKEVLKGVDFEVQRGEIFALLGSNGAGKTTTVNILSTLMKQDGGEVSICGFDVQRQPDHVRQSISLTGQFAALDGMLTGRENLIMIAKLRGVSNPAQVADNLLARFSLTDAANQRADQYSGGMKRRLDIAMNLIGAPAIIFLDEPTTGLDPEARIEVWDTVKELASSGTTILLTTQYLEEAEQLADRIAILHGGKIITTGTLAELKEMFPPAKVEYIEKQPTLEEIFLAIIGKKEEM
>NZ_CP043830.1|WP_000891987.1|3222821_3223163_-|DUF1048-domain-containing-protein
MLEMFKKLIGDKKEYKMMMARVEALPEDYQFVFKKIQNYMWNFSAGNGMDMLHIQYELIDLFEAGAAEGRQVLDITGDDVASFADELVANAKTYVSKYREDLNESIMTKLRKK
>NZ_CP043830.1|WP_000429488.1|3223238_3223559_-|PadR-family-transcriptional-regulator
MENLTEMLKGSLEGCVLEIISRRETYGYEITRHLNDLGFTEVVEGTVYTILVRLEKKKLVNIEKKPSDMGPPRKFYSLNEEGRQELELFWKKWDFVSSKINVLKSK
>NZ_CP043830.1|WP_002093521.1|3224045_3225332_-|hydroxylamine-reductase
MFCYQCEQTPTGGCKVMGVCGKNETIASLQDTIVFGLKGIAAYRTHAAQLGYTDAFVDATTQEALYMTLTNSNFNEQEHIDMAMKVGKSALRVMELLDEAHTNHFGVPEPVQITQNRVEGKAIVVTGHNLFALEELLKQTEGKDINIYTHSEMLPAHGYPQLKKYKHLKGNIGKAWYDQRRLFEKFTGAILATTNCVMPIKGSYSDRFFSYDIAGLEGIQKIENDDFTPLIQKTLELPEVHMESDEQLVTGFHHNTVLSLAPEIIDAVKEGKIKRFFVIAGCDAPGKGGEYYRELATSLPPETVILTTSCGKFRFNDVDYGVVPGTEIPRYIDLGQCNNSISTVKIAAALADAFQCEVNELPVSIVLSWFEQKAVAILLGLFSLGIQDIRIGPKAPEFISPGVLDVLQETFGLKLITNAAEDMAMMLS
>NZ_CP043830.1|WP_000742460.1|3226072_3226846_-|BcII-family-subclass-B1-metallo-beta-lactamase
MKKNTLLKLGVCVSLLGITQFISTISSVKAEQKLEQKVIKNETGTISISQLNKNVWVHTELGYFNGEAVPSNGLVLTTSKGLVLVDSSWDDKLTKELIEMVEKKFKKRVTDVIITHAHADRIGGITTLKERGIKAHSTALTAELAKKSGYEEPLGDLQTITSLKFGNTKVETFYPGKGHTEDNIVVWLPQYQILAGGCLVKSAEAKDLGNVADAYVNEWSVSIGNVLKRYKNMNSVVPGHGDVGDKGLLLHTLDLLK
>NZ_CP043830.1|WP_000739854.1|3226982_3227720_-|glycoside-hydrolase-family-25-protein
MKKNLFIGGIFTLISVISVVVYLVFQGIFIPNQISADKYEIKGVDVASYQGDIDWRELEKQNMKFAFIKATEGSSFVDEYFSKNWTNANKTDMRIGAYHFFSFDSKGETQAEQFIRTVPKYKQALPPVIDVEFYANKKDNPPKREDVAKELSVMIEMLEKHYGKKVILYATQEAYDLYIKDGYPKCDIWIRSVLTKTSLSDERKWTFWQYTNRGKLSGYNGKEKYIDLNVFYGNEEEFENYGVKG
>NZ_CP043830.1|WP_001028133.1|3227754_3228036_-|hypothetical-protein
MNIVEFQRYVSNFSKEKGFQDTTIEERTIYTMAELGELAEVILKRDTIQDAKREIGLEMFDVIWNVCDLANKLNVDLEKAFEEKMKINKKREW

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Crispr_ID: NZ_CP043830_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043830_2

3517830-3519312

Orphan

Consensus_repeat	Method
CTCGAGGTANNACNGGNGCNACTGGNGCTACTGGACCTCAAGGNGTTCAAGG	CRT

18 spacers

The CRISPR arrays of NZ_CP043830_2

>merge|NZ_CP043830|2|3517830-3519312|CRT
CTCGAGGTAACACGGGCGCTACTGGTGCTACTGGGCCTACTGGACCTCGAGGTAACACGGGCGCTACTGGTGCTACTGGGCCTACTGGACCTCGAGGTAACACGGGCGCTACCGGTGCTACTGGACCTACTGGACCTCGAGGTAACACGGGCGCTACCGGTGCTACTGGACCTACTGGACCTCGAGGTAACACGGGCGCTACTGGTGCTACTGGACCTACTGGACCTCGAGGTAACACGGGCGCTACCGGTGCTACTGGACCTACTGGACCTCGAGGTAACACGGGCGCTACCGGTGCTACTGGACCTACTGGACCTCGAGGTAACACGGGCGCTACCGGTGCTACTGGACCTACTGGACCTCGAGGTAACACGGGCGCTACCGGTGCTACTGGACCTACTGGACCTCGAGGTAACACGGGCGCTACCGGTGCTACTGGACCTACTGGACCTCGAGGTAACACTGGCGCTACTGGACCTCAAGGCGTTCAAGGTAACACTGGTGCTACCGGTGCCACGGGACCTCAAGGTGCTCAAGGTAACACTGGCGCTACTGGACCTCAAGGCGTTCAAGGTAACACTGGCGCTACCGGTGCTACTGGACCTCAAGGTAACACTGGGGCTACTGGCGCTACTGGTGCCACTGGACCTCAAGGTGTTCAAGGTAACACTGGGGCTACTGGTGCCACGGGCGCTACTGGACCTCAAGGCGTTCAAGGTAACACTGGGGCTACCGGTGCCACGGGACCTCAAGGTGCTCAAGGTAACACTGGCGCTACTGGACCTCAAGGTGTTCAAGGTAACACTGGGGCTACTGGTGCCACGGGACCTCAAGGTATTCAAGGTAACACAGGGGCTACTGGTGCCACGGGACCTCAAGGTATTCAAGGTAACACGGGGGCTACCGGTGCCACTGGCGCTACTGGACCTCAAGGCGTTCAAGGTAACACAGGGGCTACTGGGGCTACCGGTGCCACTGGCGCTACTGGACCTCAAGGCGTTCAAGGTAACACAGGTGCCACGGGTGCTACTGGACCTCAAGGTAACACAGGGGCTACTGGCGCTACTGGTGCCACTGGACCTCAAGGTGTTCAAGGTAACACAGGGGCTACTGGGGCTACCGGTGCCACTGGCGCTACTGGACCTCAAGGCGTTCAAGGTAACACAGGGGCTACTGGGGCTACCGGTGCCACTGGCGCTACTGGACCTCAAGGCGTTCAAGGTAACACAGGGGCTACTGGGGCTACCGGTGCCACTGGCGCTACTGGACCTCAAGGCGTTCAAGGTAACACAGGGGCTACTGGGGCTACTGGGGCTACCGGTGCCACTGGCGCTACTGGCGCTACTGGACCTCAAGGCGTTCAAGGTAACACAGGGGCTACCGGTGCCACTGGCGCTACTGGACCTCAAGGCGTTCAAGGTAACACAGGGGCTACTGGGGCTACCGGTGCCACTGGCGCTACTGGACCTCAAGGCGTTCAAGG

>NZ_CP043830|2|1|3517830-3519312|CRT
CTCGAGGTAACACGGGCGCTACTGGTGCTACTGGGCCTACTGG	ACCTCGAGGTAACACGGGCGCTACTGGTGCTACTGGGCCTACTGGAC
CTCGAGGTAACACGGGCGCTACCGGTGCTACTGGACCTACTGG	ACCTCGAGGTAACACGGGCGCTACCGGTGCTACTGGACCTACTGGAC
CTCGAGGTAACACGGGCGCTACTGGTGCTACTGGACCTACTGG	ACCTCGAGGTAACACGGGCGCTACCGGTGCTACTGGACCTACTGGAC
CTCGAGGTAACACGGGCGCTACCGGTGCTACTGGACCTACTGG	ACCTCGAGGTAACACGGGCGCTACCGGTGCTACTGGACCTACTGGAC
CTCGAGGTAACACGGGCGCTACCGGTGCTACTGGACCTACTGG	ACCTCGAGGTAACACGGGCGCTACCGGTGCTACTGGACCTACTGGAC
CTCGAGGTAACACTGGCGCTACTGGACCTCAAGGCGTTCAAGG	TAACACTGGTGCTACCGGTGCCACGGGACCTCAAGGTG
CTCAAGGTAACACTGGCGCTACTGGACCTCAAGGCGTTCAAGG	TAACACTGGCGCTACCGGTGCTACTGGACCTCAAGGTAACACTGGGG
CTACTGGCGCTACTGGTGCCACTGGACCTCAAGGTGTTCAAGG	TAACACTGGGGCTACTGGTGCCACGGGCGCTACTGGACCTCAAGGCGTTCAAGGTA
ACACTGGGGCTACCGGTGCCACGGGACCTCAAGGTGCTCAAGG	TAACACTGGCGCTACTGGACCTCAAGGTGTTCAAGGTA
ACACTGGGGCTACTGGTGCCACGGGACCTCAAGGTATTCAAGG	TAACACAGGGGCTACTGGTGCCACGGGACCTCAAGGTATTCAAGGTAACACGGGGG
CTACCGGTGCCACTGGCGCTACTGGACCTCAAGGCGTTCAAGG	TAACACAGGGGCTACTGGGG
CTACCGGTGCCACTGGCGCTACTGGACCTCAAGGCGTTCAAGG	TAACACAGGTGCCACGGGTGCTACTGGACCTCAAGGTAACACAGGGG
CTACTGGCGCTACTGGTGCCACTGGACCTCAAGGTGTTCAAGG	TAACACAGGGGCTACTGGGG
CTACCGGTGCCACTGGCGCTACTGGACCTCAAGGCGTTCAAGG	TAACACAGGGGCTACTGGGG
CTACCGGTGCCACTGGCGCTACTGGACCTCAAGGCGTTCAAGG	TAACACAGGGGCTACTGGGG
CTACCGGTGCCACTGGCGCTACTGGACCTCAAGGCGTTCAAGG	TAACACAGGGGCTACTGGGGCTACTGGGG
CTACCGGTGCCACTGGCGCTACTGGCGCTACTGGACCTCAAGG	CGTTCAAGGTAACACAGGGG
CTACCGGTGCCACTGGCGCTACTGGACCTCAAGGCGTTCAAGG	TAACACAGGGGCTACTGGGG
CTACCGGTGCCACTGGCGCTACTGGACCTCAAGGCGTTCAAGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043830.1\|WP_000656783.1\|3510945_3511335_-\|transcriptional-repressor-GlnR	unknown	unknown	gnl\|CDD\|133380
NZ_CP043830.1\|WP_000734608.1\|3523352_3524285_-\|3D-domain-containing-protein	unknown	unknown	gnl\|CDD\|226112
NZ_CP043830.1\|WP_000640839.1\|3526502_3527414_-\|1-phosphofructokinase	unknown	unknown	gnl\|CDD\|238570
NZ_CP043830.1\|WP_000504365.1\|3521910_3522864_-\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	unknown	unknown	gnl\|CDD\|234626
NZ_CP043830.1\|WP_000135333.1\|3509562_3510897_-\|type-I-glutamate--ammonia-ligase	unknown	unknown	gnl\|CDD\|273198
NZ_CP043830.1\|WP_000814421.1\|3523044_3523290_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043830.1\|WP_000450335.1\|3516257_3517223_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271175
NZ_CP043830.1\|WP_000312260.1\|3514141_3514765_+\|trimeric-intracellular-cation-channel-family-protein	unknown	unknown	gnl\|CDD\|225415
NZ_CP043830.1\|WP_000957292.1\|3527410_3528163_-\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
NZ_CP043830.1\|WP_000409433.1\|3508699_3509359_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|224885
NZ_CP043830.1\|WP_000813896.1\|3521664_3521889_-\|RNA-chaperone-Hfq	unknown	unknown	gnl\|CDD\|179001
NZ_CP043830.1\|WP_001179084.1\|3528321_3529485_-\|iron-containing-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|341466
NZ_CP043830.1\|WP_000228316.1\|3529602_3530145_-\|DUF420-domain-containing-protein	unknown	unknown	gnl\|CDD\|225204
NZ_CP043830.1\|WP_000460314.1\|3511510_3512782_-\|methionine-gamma-lyase-family-protein	unknown	unknown	gnl\|CDD\|311036
NZ_CP043830.1\|WP_000181509.1\|3514865_3515003_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043830.1\|WP_000704651.1\|3524632_3526489_-\|PTS-fructose-transporter-subunit-IIABC	unknown	unknown	gnl\|CDD\|236740
NZ_CP043830.1\|WP_000391426.1\|3512774_3514049_-\|GTPase-HflX	unknown	unknown	gnl\|CDD\|274455
NZ_CP043830.1\|WP_000438193.1\|3515035_3515992_-\|stage-V-sporulation-protein-K	unknown	unknown	gnl\|CDD\|163057
NZ_CP043830.1\|WP_002039366.1\|3530463_3530802_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043830.1\|WP_000283429.1\|3508233_3508497_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274987

Protein	Function_ID	Function_description	E-value
NZ_CP043830.1\|WP_000656783.1\|3510945_3511335_-\|transcriptional-repressor-GlnR	gnl\|CDD\|133380	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators. Helix-turn-helix (HTH) transcription regulator GlnR and related proteins, N-terminal domain. The GlnR and TnrA (also known as ScgR) proteins have been shown to regulate expression of glutamine synthetase as well as several genes involved in nitrogen metabolism. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	1.14369e-23
NZ_CP043830.1\|WP_000734608.1\|3523352_3524285_-\|3D-domain-containing-protein	gnl\|CDD\|226112	COG3584, COG3584, Uncharacterized protein conserved in bacteria [Function unknown].	6.15616e-37
NZ_CP043830.1\|WP_000640839.1\|3526502_3527414_-\|1-phosphofructokinase	gnl\|CDD\|238570	cd01164, FruK_PfkB_like, 1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose 6-phosphate pathway, which responsible for breakdown of the galactose moiety during lactose metabolism by bacteria such as L. lactis.	4.23304e-141
NZ_CP043830.1\|WP_000135333.1\|3509562_3510897_-\|type-I-glutamate--ammonia-ligase	gnl\|CDD\|273198	TIGR00653, Glutamine_synthetase, glutamine synthetase, type I. Alternate name: glutamate--ammonia ligase. This model represents the dodecameric form, which can be subdivided into 1-alpha and 1-beta forms. The phylogeny of the 1-alpha and 1-beta forms appears polyphyletic. E. coli, Synechocystis PCC6803, Aquifex aeolicus, and the crenarcheon Sulfolobus acidocaldarius have form 1-beta, while Bacillus subtilis, Thermotoga maritima, and various euryarchaea has form 1-alpha. The 1-beta dodecamer from the crenarcheon Sulfolobus acidocaldarius differs from that in E. coli in that it is not regulated by adenylylation. [Amino acid biosynthesis, Glutamate family].	0
NZ_CP043830.1\|WP_000504365.1\|3521910_3522864_-\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	gnl\|CDD\|234626	PRK00091, miaA, tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed.	2.08152e-169
NZ_CP043830.1\|WP_000957292.1\|3527410_3528163_-\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	1.34438e-80
NZ_CP043830.1\|WP_000450335.1\|3516257_3517223_+\|site-specific-integrase	gnl\|CDD\|271175	cd00397, DNA_BRE_C, DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine based site-specific recombinases (integrases) that share the same fold in their catalytic domain containing conserved active site residues. The best-studied members of this diverse superfamily include Human topoisomerase I, the bacteriophage lambda integrase, the bacteriophage P1 Cre recombinase, the yeast Flp recombinase, and the bacterial XerD/C recombinases. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. The enzymes differ in that topoisomerases cleave and then rejoin the same 5' and 3' termini, whereas a site-specific recombinase transfers a 5' hydroxyl generated by recombinase cleavage to a new 3' phosphate partner located in a different duplex region. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	7.06635e-12
NZ_CP043830.1\|WP_000312260.1\|3514141_3514765_+\|trimeric-intracellular-cation-channel-family-protein	gnl\|CDD\|225415	COG2860, COG2860, Predicted membrane protein [Function unknown].	1.00996e-60
NZ_CP043830.1\|WP_000409433.1\|3508699_3509359_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|224885	COG1974, LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms].	2.85952e-30
NZ_CP043830.1\|WP_000813896.1\|3521664_3521889_-\|RNA-chaperone-Hfq	gnl\|CDD\|179001	PRK00395, hfq, RNA-binding protein Hfq; Provisional.	3.4363e-41
NZ_CP043830.1\|WP_001179084.1\|3528321_3529485_-\|iron-containing-alcohol-dehydrogenase	gnl\|CDD\|341466	cd08187, BDH, Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process. The butanol dehydrogenase (BDH) is involved in the final step of the butanol formation pathway in anaerobic micro-organism. Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process. Activity in the reverse direction is 50-fold lower than that in the forward direction. The NADH-BDH has higher activity with longer chained aldehydes and is inhibited by metabolites containing an adenine moiety. This protein family belongs to the so-called iron-containing alcohol dehydrogenase superfamily. Since members of this superfamily use different divalent ions, preferentially iron or zinc, it has been suggested to be renamed to family III metal-dependent polyol dehydrogenases. This family also includes E. coli YqhD enzyme, an NADP-dependent dehydrogenase whose activity measurements with several alcohols demonstrate preference for alcohols longer than C3. The active site of YqhD contains a Zn metal, and a modified NADPH cofactor bearing OH groups on the saturated C5 and C6 atoms, possibly due to oxygen stress on the enzyme, which would functionally work under anaerobic conditions.	0
NZ_CP043830.1\|WP_000228316.1\|3529602_3530145_-\|DUF420-domain-containing-protein	gnl\|CDD\|225204	COG2322, COG2322, Predicted membrane protein [Function unknown].	1.75148e-56
NZ_CP043830.1\|WP_000460314.1\|3511510_3512782_-\|methionine-gamma-lyase-family-protein	gnl\|CDD\|311036	pfam06838, Met_gamma_lyase, Methionine gamma-lyase. This is a putative pyridoxal 5'-phosphate-dependent methionine gamma-lyase enzyme involved in methionine catabolism.	0
NZ_CP043830.1\|WP_000704651.1\|3524632_3526489_-\|PTS-fructose-transporter-subunit-IIABC	gnl\|CDD\|236740	PRK10712, PRK10712, PTS system fructose-specific transporter subunits IIBC; Provisional.	9.24171e-144
NZ_CP043830.1\|WP_000391426.1\|3512774_3514049_-\|GTPase-HflX	gnl\|CDD\|274455	TIGR03156, GTP_HflX, GTP-binding protein HflX. This protein family is one of a number of homologous small, well-conserved GTP-binding proteins with pleiotropic effects. Bacterial members are designated HflX, following the naming convention in Escherichia coli where HflX is encoded immediately downstream of the RNA chaperone Hfq, and immediately upstream of HflKC, a membrane-associated protease pair with an important housekeeping function. Over large numbers of other bacterial genomes, the pairing with hfq is more significant than with hflK and hlfC. The gene from Homo sapiens in this family has been named PGPL (pseudoautosomal GTP-binding protein-like). [Unknown function, General].	0
NZ_CP043830.1\|WP_000438193.1\|3515035_3515992_-\|stage-V-sporulation-protein-K	gnl\|CDD\|163057	TIGR02881, Stage_V_sporulation_protein_K, stage V sporulation protein K. Members of this protein family are the stage V sporulation protein K (SpoVK), a close homolog of the Rubisco expression protein CbbX (TIGR02880) and a members of the ATPase family associated with various cellular activities (pfam00004). Members are strictly limited to bacterial endospore-forming species, but are not universal in this group and are missing from the Clostridium group. [Cellular processes, Sporulation and germination].	1.47829e-155
NZ_CP043830.1\|WP_000283429.1\|3508233_3508497_-\|hypothetical-protein	gnl\|CDD\|274987	TIGR04111, conserved_hypothetical_protein, phage-associated protein, BcepMu gp16 family. Members of this protein family occur in Burkholderia phage BcepMu, Pseudomonas phage B3, and Burkholderia phage KS10, and many bacterial putative prophage regions. The member from Burkholderia phage BcepMu is named gp16. Homology suggests DNA-binding activity. [Mobile and extrachromosomal element functions, Prophage functions].	0.00626223

>NZ_CP043830.1|WP_000450335.1|3516257_3517223_+|site-specific-integrase
METTEFHDTIQAFSIFLLNKGRKTSTIKRYVYDIEDFGHWLEKNKKLPSSNIWATLCTKDYEDYFSDLKTNRNYSEKTMHRVFIVLNRMNHFLNIPNPLKNMEISIQPDRALRNEDFISSNEEKKLKRIVTSLEGLSEKQRPVRPLLMDRNITILNLLIDYGLSLQELTALTMYHVHFETNTLSIPATAGVERTITLTKEDKKQLYTYYKSIPEPVRPKYHSNDPLFVAFDFNRGTYRWVYENDSPKGLTEIAIQKMIRLEVARANLRKGISGQHFRNTYILNLIKKETPESEIIKLAGFKSKVSLKRYYKYAENRKNALL
>NZ_CP043830.1|WP_000438193.1|3515035_3515992_-|stage-V-sporulation-protein-K
MEQSMRKKNNNQINIVLNHRKKISLPASENKTEISNETTIKHEMLQRIEEEMGKLVGMDDIKKIIKEIYAWIYVNKKRQEMGLKSEKQVLHMLFKGNPGTGKTTVARMIGKLLFEMNILSKGHLVEAERADLVGEYIGHTAQKTRDLIKKAMGGILFIDEAYSLARGGEKDFGKEAIDTLVKHMEDKQHGFVLILAGYSREMNHFLSLNPGLQSRFPFIIEFADYSVNQLLEIGKRMYEEREYQLSKEAEWKFRDHLHAVKYSSQITSFSNGRYVRNIVEKSIRTQAMRLLQEDTYDKYDLIGISSVDLMLEEETHST
>NZ_CP043830.1|WP_000181509.1|3514865_3515003_+|hypothetical-protein
MTNHVNKGAQKSSVNQFGHDSNSAHEKSAKMERFHKSHQEKEKKE
>NZ_CP043830.1|WP_000312260.1|3514141_3514765_+|trimeric-intracellular-cation-channel-family-protein
MAWEIFSIIGTIAFALSGAIVAMEEDYDIFGVYILGMATAFGGGALRNLLIGYPIVAFWQQDMLFQIALLSMTIIFLFPNKLIKHWKKWENITDAIGLSAFAIQGALYAQKLNLPISATIVAAVLTGIGGGIIRDLLARRKPLVLRAEVYAFWTILAGFLIGAQIIVSDWALYTLFILIVCFRMLSIHYKWHLPHRRIDTNERSMHK
>NZ_CP043830.1|WP_000391426.1|3512774_3514049_-|GTPase-HflX
MEEKEKVILVGCQLQQDDDEQFMHSMKELASLAKTARAKVLVSTTQKRPKFHPVTYIGKGKLEELTMLTEELEPDVIIFNNELTPSQIRNLSSVLDARVIDRTQLILDIFAQRAKSREGKLQVELAQLQYTMPRLMGQGLSLSRLGGGIGTRGPGETKLETDRRHIRSRIDEIKKQLAVVVEHRKRYRERRKDNKVFQVSLIGYTNAGKSTLFNRLTEADTFEENLLFATLDPTTRKMPLPYGYTVLLTDTVGFIQDLPTSLIAAFRSTLEEAGEADVILHVVDSADPNYVGHEKTVKKLLSELEINHIPIITLYNKKDALHQNFIPFPKSDFLMTSAFEEIDLLHIKEAIETKMKEEMDPYQVEIPPSEGKLLTLLKTETLLTKMEFLEDKFVYSCTGYIFAYSPYNGQLKRFLVEEGENDNV
>NZ_CP043830.1|WP_000460314.1|3511510_3512782_-|methionine-gamma-lyase-family-protein
MFDRLKNGEKMAPIVKEVESQITEVHKRADEVIESNQFRVLENFRKHKISDSHFIPTTGYGYDDIGRDTLEKVYADVFGAEAGLVRPQIISGTHAISTALFGILRPGDELLYITGKPYDTLEEIVGVRGKGVGSFKEYNIGYNAVSLTEEGLVDFEAVAAAIHSNTKMIGIQRSKGYATRPSFTISQIKEMISFVKEIKPDVVVFVDNCYGEFIEEQEPCHVGADLMAGSLIKNPGGGIVKTGGYIVGKEQYVEACAYRLTSPGIGAEAGASLYSLQEMYQGFFLAPHVAGQALKGAIFTAAFLEKLGMNTSPAWNAPRTDLIQSVQFDDKDRMIAFCQAIQYASPINSHFTPYANYMPGYEDDVIMAAGTFIQGASIELSADGPIRPPYVAYVQGGLTYSHVKIAICSAIDALIEKKLLTIS
>NZ_CP043830.1|WP_000656783.1|3510945_3511335_-|transcriptional-repressor-GlnR
MKEDRRSAPLFPIGIVMDLTQLSARQIRYYEEHNLVSPTRTKGNRRLFSFNDVDKLLEIKDLLDQGLNMAGIKQVLLMKENQTEAVKVKEETKEISKTELRKILRDELQHTGRFNRTSLRQGDISRFFH
>NZ_CP043830.1|WP_000135333.1|3509562_3510897_-|type-I-glutamate--ammonia-ligase
MARYTKEDIFRLAKEENVKYIRLQFTDLLGVIKNVEIPVSQLTKALDNKMMFDGSSIEGFVRIEESDMYLYPDLDTWVIFPWTAEKGKVARLICDIYTADGAPFDGDPRNNLKRVLKEMEALGFSDFNLGPEPEFFLFKVDEKGNPTLELNDNGGYFDLAPMDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYANAIRSCDDIQTFKLVVKTIARKHGLHATFMPKPLYGVNGSGMHCNLSLFKNGENVFFDQNGDLQLSDDARHFIAGILKHAPAFTAVANPTVNSYKRLVPGYEAPCYVAWSAQNRSPLVRIPASRGISTRVEVRSVDPAANPYLVMATLLAAGLDGIKNKLTPPAAVDRNIYVMTKEEREEAGIVDLPATLAQALVTLQSNEVVCSALGEHLLEHFIEAKEIEWDIFRTQVHQWERDQYMSLY
>NZ_CP043830.1|WP_000409433.1|3508699_3509359_+|helix-turn-helix-domain-containing-protein
MEKAKIVTRLIKEAGYSKRAFAEKIGLPPTTLQSMLSRGIGKASVDNVIKVCKGLGITTDDLEVLTTKGDNTVKEEVSIYETIQNDQSNIIHIPIIGSVAAGTPIFAEENIEGYLPMLSTFLNKRKKYFYLTVKGTSMNLEFPDGSYVLVEETPYVENGQIAVVKVNGYDATVKKISKSGSIITLIPLSNDPIHEPQTYDLSAEDVKIIGRVVQAVKNY
>NZ_CP043830.1|WP_000283429.1|3508233_3508497_-|hypothetical-protein
MYPNLRAEMARKGIVITQISSHLNLRYATVCDKINGKFRFYYDEALEIKETFFPDHNLEYLFEFEENKPNCSVKRNPTFLEHKILNF
>NZ_CP043830.1|WP_000813896.1|3521664_3521889_-|RNA-chaperone-Hfq
MKQSINIQDQFLNQLRKENTFVTLYLLNGFQLRGLIKGFDNFTVLLETEGKQQLIYKHAISTFVPQKNVSIELE
>NZ_CP043830.1|WP_000504365.1|3521910_3522864_-|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA
MGEMQREKVAVIIGPTAVGKTKLSIDLAKALNGEIISGDSMQIYRTMDIGTAKVTKEEMDGIPHYMVDIKDPEDSFSVAEFQERVRKHIREITERGKLPIIVGGTGLYIQSVLFDYQFTDDAGDAIYREQMEKLAQERGVEYVHEKLQEVDPESAERIHANNVRRVIRALEIFHTTGEKMSDQLEKQENELLYDVSLIGLTMDREMLYDRINLRVDLMMEQGLLEEVEGLYNRGIRDCQSIQAIGYKEVYDYFENRVSLEEAVSQLKTNSRRYAKRQLTWFRNKMDVTWFDVTDGEKTSEILRYIEGKLQLKSNNSK
>NZ_CP043830.1|WP_000814421.1|3523044_3523290_+|hypothetical-protein
MKQSTINFSSLTKDLILATATKEQNCSQEELYFALNCLLRSFHSTLQETTLHPENKNTEYMQTQFCSAYKILTGTTIYPFQ
>NZ_CP043830.1|WP_000734608.1|3523352_3524285_-|3D-domain-containing-protein
MKKLLGIATAAVFGLGIFAGSAKAETIVTTDVLNVRENPNVESKLVGKMLSGNKLDVINTENGWSKIKLDGKEAFVSAEFTKSTYYVTANVLNIRAGANTDSEILGKFNKNDLIETTNQVQNEWLQFDYNGKVAYVHVPFLTGTAPVIEKKEVVTQEEVPERVNTPVKNNKAVKSKESVKNVESNKPVVKQQSTTKQVAKSTQTSAPAGGREITVEATAYTANPSENGTYGGRVLTAMGHDLTANPNMKVIAVDPKVIPLGSKVWVEGYGEAIAGDTGGAIKGNRIDVLVGSDGSANSWGRKSVKVKVIQ
>NZ_CP043830.1|WP_000704651.1|3524632_3526489_-|PTS-fructose-transporter-subunit-IIABC
MKITELLKRDTVIMNLTASNKEAVIDELVEKLSGANRLNSKTEFKEAILKRESQSTTGIGEGIAIPHAKTKAVKQPAICFGRSVSGINYESLDGQPAHLFFMIAASEGANNTHLETLSRLSTLLMDEGFRKQLLEAKDEEELLRLFDEKENEKEEEVEVAKPEGDEPYVLAVTACPTGIAHTYMAADSLKAKAAELGIAIKVETNGSTGIKNGLTKEDIERATAIIVAADKQVEVNRFAGKHVIQVPVADGIRKTEKLLNRAVKQDAPIFKGVKENGKSESIEKEKGLGIYKHLMSGVSNMLPFVVGGGILIALAFSFGGIKAEGPLAELFMSIGGGKTGAFLFLVPILAGFIASSIADRPGFMPGVVGGFLAAHANAGFLGGLIAGFLAGYVVLGLKRLFSGLPAQLEGIKPVLLYPVFGLLITGVVMQKVVNPPVVALNEMLTGWLNGLNGTNAILLGLILGGMMAIDMGGPINKAAFTFGIAAIEAQNFGVHSAVMAGGMVPPLAIAFATTFFKTKFTEAERKSGLTNYIMGASFITEGAIPFAAADPIRVIVSCVVGSSIAGALSMLFQITLPAPHGGLFVIALVNKPLLYIFSILVGTAISALMMGIWKKKVK
>NZ_CP043830.1|WP_000640839.1|3526502_3527414_-|1-phosphofructokinase
MIYTVTLNPSIDYVVQVNSFDLGTVNRAEKDMKFPGGKGINVSRVLHRLGVENVALGFTGGFTGQFIQDVLHDEGVTTNFVQVDEDTRINVKIKGEEETELNGQGPIVTKEQFGQLMKKIESMQREDCVVLAGSIPASIQNTFYESIAAFGAEKGIRVVVDASGSALQHVIKNKPFLIKPNHHELGELFGVELSTVEEILPYGRKLVEQGVENVIVSMAGDGALLFTAEGIYEATVPKGVVINSVGAGDSLVAGFVGKYEQTKEIEKAFQYGVATGSATAFSADLCKKEKVEELLSQVIVVKR
>NZ_CP043830.1|WP_000957292.1|3527410_3528163_-|DeoR/GlpR-transcriptional-regulator
MLTPERHQMILQLVKEQKVVKLQQLVERTESSESTIRRDLAQLEKQRLLKRVHGGASVLTAKGQEPTMTEKSSKNIQIKHQIAKYAATIVEQGDCIYLDAGSTTFEMIPFLINKDVTVVTNGLMHIEALVENNIRAYLLGGMMKSRTKALIGAMAQESMQKYRFDKCFLGANGVHEQFGFTTPDPEEALLKQMALTLANEGYFLIDESKFSEVAFAKIANVEDANIITNHLEMDLEKYKRQTNVIEADKQ
>NZ_CP043830.1|WP_001179084.1|3528321_3529485_-|iron-containing-alcohol-dehydrogenase
MQNFVFRNPTKLIFGKGQLEQLKTEIPQFGKKVLLVYGGGSIKRNGIYDNVISILKDINAEVFELTGVEPNPRVSTVKKGIQICKENGVEFILAVGGGSVIDCTKAIAAGSKYDGDVWDIVTKKAFASEALPFGTVLTLAATGSEMNAGSVITNWETNEKYGWGSPVTFPQFSILDPVHTASVPKDQTIYGMVDIMSHVLEQYFHHGTNTELQDRYCESVLRTVIETAPKLLSDLENYEHRETILYCGTMALNGILAMGVKGDWATHNIEHAVSAVHDIPHGGGLAILFPNWMKHVIDENVSRFKQFAIRVFDIETDGKTDKEVALEGIEALRQFWTSIEAPVALSDYTIGENEIDLMADKAMAYGEFGNFKKLNKDDVLNIYKASL
>NZ_CP043830.1|WP_000228316.1|3529602_3530145_-|DUF420-domain-containing-protein
MVDQSTNQKSYAPIVITLSVIVNAIILFLFFGPVGYEGEVHFDVTILPMLNAIFNSFTFVFLLAALYSIIKKNVKMHRGFILAAFTTTLLFCVSYLSYHYLAPATHFGGEGFIKYVYFIILITHIILAAIIVPLALFALVFGFTNQLTRHRKIVRWTMPIWLYVSLSGVIVYLMISPYYQ
>NZ_CP043830.1|WP_002039366.1|3530463_3530802_-|hypothetical-protein
MVKKEGGMMMEEYVLELYNLLYTTEWQDIVSFLGIVFCMKIVIVYMEEQGMFYSFSSPFDVQREPLLNYAKVNYEQIPFVLFFMIRFITAIVKKKESDDEECHVTCNIANVF

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Crispr_ID: NZ_CP043830_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP043830_3

4987831-4987979

Orphan

Consensus_repeat	Method
GTTGATTTCTCTTCTTTTTGAGA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP043830_3

>merge|NZ_CP043830|3|4987831-4987979|CRISPRCasFinder
GTTGATTTTTCTTCTTTCTTCGTTTCTTCTTGCTTACCGCTTGTCTCTTTATCACTAGTCGAACCGCTTGTTGATTTCTCTTCTTTTTGAGACTTATCTTCTGTTTTACTTTCTGGTTTCGTGCTCGTTGACTTCTCTTCTTTTTGAGA

>NZ_CP043830|3|2|4987831-4987979|CRISPRCasFinder
GTTGATTTTTCTTCTTTCTTCGT	TTCTTCTTGCTTACCGCTTGTCTCTTTATCACTAGTCGAACCGCTT
GTTGATTTCTCTTCTTTTTGAGA	CTTATCTTCTGTTTTACTTTCTGGTTTCGTGCTC
GTTGACTTCTCTTCTTTTTGAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP043830.1\|WP_149890042.1\|4982549_4983293_-\|capsular-biosynthesis-protein	unknown	unknown	gnl\|CDD\|226453
NZ_CP043830.1\|WP_149890041.1\|4981858_4982560_-\|polysaccharide-biosynthesis-tyrosine-autokinase	unknown	unknown	gnl\|CDD\|349772
NZ_CP043830.1\|WP_149890039.1\|4979861_4980743_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|224131
NZ_CP043830.1\|WP_098009789.1\|4998671_5000534_-\|NADH-quinone-oxidoreductase-subunit-L	unknown	unknown	gnl\|CDD\|235836
NZ_CP043830.1\|WP_000170852.1\|4989570_4990413_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP043830.1\|WP_000931959.1\|4984583_4985018_-\|3-hydroxyacyl-ACP-dehydratase-FabZ	unknown	unknown	gnl\|CDD\|234568
NZ_CP043830.1\|WP_149890038.1\|4977948_4979760_-\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|224011
NZ_CP043830.1\|WP_000411271.1\|4993100_4994405_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|236486
NZ_CP043830.1\|WP_000057885.1\|4995200_4995437_-\|DUF1146-domain-containing-protein	unknown	unknown	gnl\|CDD\|227173
NZ_CP043830.1\|WP_141524368.1\|4986823_4987096_-\|sporulation-transcriptional-regulator-SpoIIID	unknown	unknown	gnl\|CDD\|378813
NZ_CP043830.1\|WP_000366977.1\|4995650_4997171_-\|NADH-quinone-oxidoreductase-subunit-NuoN	unknown	unknown	gnl\|CDD\|235603
NZ_CP043830.1\|WP_098064415.1\|4990592_4991600_-\|LytTR-family-transcriptional-regulator-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP043830.1\|WP_000008898.1\|4987402_4987537_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP043830.1\|WP_000144458.1\|4988866_4989571_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|372253
NZ_CP043830.1\|WP_000457991.1\|4985511_4986513_-\|rod-shape-determining-protein	unknown	unknown	gnl\|CDD\|237563
NZ_CP043830.1\|WP_079519735.1\|4994444_4995155_-\|YwmB-family-TATA-box-binding-protein	unknown	unknown	gnl\|CDD\|370056
NZ_CP043830.1\|WP_000672621.1\|4991827_4992847_-\|stage-II-sporulation-protein-D	unknown	unknown	gnl\|CDD\|274332
NZ_CP043830.1\|WP_000998954.1\|4997172_4998675_-\|NADH-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl\|CDD\|235622
NZ_CP043830.1\|WP_149890040.1\|4980982_4981750_-\|tyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|226870
NZ_CP043830.1\|WP_149890043.1\|4983554_4984232_-\|polysaccharide-biosynthesis-tyrosine-autokinase	unknown	unknown	gnl\|CDD\|349772

Protein	Function_ID	Function_description	E-value
NZ_CP043830.1\|WP_149890042.1\|4982549_4983293_-\|capsular-biosynthesis-protein	gnl\|CDD\|226453	COG3944, COG3944, Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane].	1.30004e-84
NZ_CP043830.1\|WP_149890041.1\|4981858_4982560_-\|polysaccharide-biosynthesis-tyrosine-autokinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	8.93224e-82
NZ_CP043830.1\|WP_149890039.1\|4979861_4980743_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	0
NZ_CP043830.1\|WP_098009789.1\|4998671_5000534_-\|NADH-quinone-oxidoreductase-subunit-L	gnl\|CDD\|235836	PRK06590, PRK06590, NADH:ubiquinone oxidoreductase subunit L; Reviewed.	0
NZ_CP043830.1\|WP_000170852.1\|4989570_4990413_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	5.55833e-90
NZ_CP043830.1\|WP_000931959.1\|4984583_4985018_-\|3-hydroxyacyl-ACP-dehydratase-FabZ	gnl\|CDD\|234568	PRK00006, fabZ, 3-hydroxyacyl-ACP dehydratase FabZ.	5.26499e-95
NZ_CP043830.1\|WP_149890038.1\|4977948_4979760_-\|polysaccharide-biosynthesis-protein	gnl\|CDD\|224011	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	0
NZ_CP043830.1\|WP_000411271.1\|4993100_4994405_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl\|CDD\|236486	PRK09369, PRK09369, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated.	0
NZ_CP043830.1\|WP_000057885.1\|4995200_4995437_-\|DUF1146-domain-containing-protein	gnl\|CDD\|227173	COG4836, COG4836, Predicted membrane protein [Function unknown].	2.16293e-23
NZ_CP043830.1\|WP_141524368.1\|4986823_4987096_-\|sporulation-transcriptional-regulator-SpoIIID	gnl\|CDD\|378813	pfam12116, SpoIIID, Stage III sporulation protein D. This stage III sporulation protein is a small DNA-binding family that is essential for gene expression of the mother-cell compartment during sporulation. The domain is found in bacteria and viruses, and is about 40 amino acids in length. It has a conserved RGG sequence motif.	1.15232e-38
NZ_CP043830.1\|WP_000366977.1\|4995650_4997171_-\|NADH-quinone-oxidoreductase-subunit-NuoN	gnl\|CDD\|235603	PRK05777, PRK05777, NADH-quinone oxidoreductase subunit NuoN.	8.50092e-151
NZ_CP043830.1\|WP_000144458.1\|4988866_4989571_-\|ABC-transporter-permease	gnl\|CDD\|372253	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family.	9.53786e-06
NZ_CP043830.1\|WP_098064415.1\|4990592_4991600_-\|LytTR-family-transcriptional-regulator-DNA-binding-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	4.51089e-32
NZ_CP043830.1\|WP_000457991.1\|4985511_4986513_-\|rod-shape-determining-protein	gnl\|CDD\|237563	PRK13928, PRK13928, rod shape-determining protein Mbl; Provisional.	0
NZ_CP043830.1\|WP_000998954.1\|4997172_4998675_-\|NADH-quinone-oxidoreductase-subunit-M	gnl\|CDD\|235622	PRK05846, PRK05846, NADH:ubiquinone oxidoreductase subunit M; Reviewed.	4.76972e-178
NZ_CP043830.1\|WP_079519735.1\|4994444_4995155_-\|YwmB-family-TATA-box-binding-protein	gnl\|CDD\|370056	pfam08680, DUF1779, TATA-box binding. TATA-box_bdg is a family of bacterial proteins. YwmB from Bacillus subtilis contains a circularly permuted TATA-box binding protein-like fold. Jian-Xiang Liu, Qi Xie, Jun Lin. Protein Structural Data Mining and Evolutionary Bioinformatic Analysis on Domains of TATA-box Binding Protein-like Fold. Life Science Journal 2014; 11(2): 298-302 (not yet in PubMed 27-02-2014).	8.08928e-33
NZ_CP043830.1\|WP_000672621.1\|4991827_4992847_-\|stage-II-sporulation-protein-D	gnl\|CDD\|274332	TIGR02870, Stage_II_sporulation_protein_D, stage II sporulation protein D. Stage II sporulation protein D (SpoIID) is a protein of the endospore formation program in a number of lineages in the Firmicutes (low-GC Gram-positive bacteria). It is expressed in the mother cell compartment, under control of Sigma-E. SpoIID, along with SpoIIM and SpoIIP, is one of three major proteins involved in engulfment of the forespore by the mother cell. [Cellular processes, Sporulation and germination].	3.69304e-131
NZ_CP043830.1\|WP_149890040.1\|4980982_4981750_-\|tyrosine-protein-phosphatase	gnl\|CDD\|226870	COG4464, CapC, Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	3.24076e-104
NZ_CP043830.1\|WP_149890043.1\|4983554_4984232_-\|polysaccharide-biosynthesis-tyrosine-autokinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	1.82196e-80

>NZ_CP043830.1|WP_000008898.1|4987402_4987537_-|hypothetical-protein
MSFLFVLSIAIILLFVLFTLYYYIAGKKEVPHHQLLEEEYDREE
>NZ_CP043830.1|WP_141524368.1|4986823_4987096_-|sporulation-transcriptional-regulator-SpoIIID
MHDYIKERTIKIGKYIVETRKTVRVIAKEFGVSKSTVHKDLTERLPEINPDLANEVKEILDYHKSIRHLRGGEATKQKYRKEDVEKPVRQ
>NZ_CP043830.1|WP_000457991.1|4985511_4986513_-|rod-shape-determining-protein
MFARDIGIDLGTANVLIHVKGKGIVLNEPSVVAIDRNTGKVLAVGEEARSMVGRTPGNIVAIRPLKDGVIADFEITEAMLKYFINKLDVKSFFSKPRILICCPTNITSVEQKAIREAAERSGGKTVFLEEEPKVAAVGAGMEIFQPSGNMVVDIGGGTTDIAVLSMGDIVTSSSIKMAGDKFDMEILNYVKRKYKLLIGERTSENIKIKVGTVFPGARSEELEIRGRDMVTGLPRTITVCSEEITEALKEDAAIIVQAAKGVLERTPPELSADIIDRGVILTGGGALLHGIDMLLAEELKVPVLIAENPMQCVAVGTGIMLENIDKLPRRALK
>NZ_CP043830.1|WP_000931959.1|4984583_4985018_-|3-hydroxyacyl-ACP-dehydratase-FabZ
MLNIEQIKEIIPHRYPFLLVDKILEVDEGKRAVGIKNVSANEEFFNGHFPDYAVMPGVLIVEALAQVGAVAVLKKEENRGRLAFFAGIDNCRFKKQVRPGDQLRLEVEMTRVRGPIGKGKAIATVDGEVACEAEITFAIGDKKE
>NZ_CP043830.1|WP_149890043.1|4983554_4984232_-|polysaccharide-biosynthesis-tyrosine-autokinase
MFGRKKRKPLRQLIAHKEPKSRITEQYRNIRTNIEFTSVDSHVRSIIVTSADPADGKTTTIANLAVVFGQQGKKVLLIGADLRKPTIQNLFAIHSSNGLTNLLSGQANLMQCIQKTDIENVYLMAAGPIPPNPAELLGSRAMDEALLEAYNMFDIILIDTPPVLAVTDAQILANKCDGIVLVVRSEKTEKDKIVKAKQILDKASGKLLGVVLNDKREEKEQYGYY
>NZ_CP043830.1|WP_149890042.1|4982549_4983293_-|capsular-biosynthesis-protein
MEETISLKELFHILKKRLAMILVIAFGAAIVSAIISFFFMTPIYQSSTQILVNQKKQEGAMFQAGEVQTNIQLTNTYKVIIKSPVILDQVNEKLNLNMTAQSLTKKINVANEKDSQVISVTAEDKNPKVARDIANATADVFKGEVAKIMNVDNVTVLSKAEVAENLSPIKPRPMLNVVIAFVVGLMASVGLAFLLEYLDNTVKKEEDVESLLGLPVLGIVARMDEETLNMKSHAPSSRKVRGQTIGS
>NZ_CP043830.1|WP_149890041.1|4981858_4982560_-|polysaccharide-biosynthesis-tyrosine-autokinase
MALNLFKKKKNHRQRRQLIAHQQPKSPISEQYRNIRTNIEFAAIDTNLHSLMVTSANPSEGKTTTTANMAVVFAQQGKKVLLIDADMRKPAMHQMFQVDNIFGLTNVLTYSERLEKCVQTTLVDNLHFLACGPIPPNPAELLGSKSMKELLGQAYSMYDLVIFDMPPILAVTDAQIMANVCDASILVVRSEATEKETAVKAKGLLESAKGKLLGVVLNDREREQGLYYYYGAN
>NZ_CP043830.1|WP_149890040.1|4980982_4981750_-|tyrosine-protein-phosphatase
MIDLHCHILHGIDDGAQTVTDSLAMAQQAVAEGIHTIVATPHHQNGKYINERTSIIHQVKQLNDELQQNEIPLKILPGQEVRLYGDLLEDYEAGKIVTLNETNKYIFIEFPSNHVPRYAEQLLYELRVKGMIPIIVHPERNAELIERPDKLYNLVSKGALTQVTAGSLLGKFGKKIKKFSLQLVEHNLTHMVASDAHNITSRGFHLAESYELIEKEFGMSVMSDLKENPYLLISGKAIYKEDPEQIRRKKLFGIF
>NZ_CP043830.1|WP_149890039.1|4979861_4980743_-|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKKVKKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAIESGIEDIIIVTGKGKRAIEDHFDHSFELEQNLLEKGKYEMLEKVQASSRINIHYIRQKEPKGLGHAVWCARKFIGNEPFAVLLGDDIVQAETPCLRQLMDQYEGTQSSVIGVQTVPENETHRYGIIDPAEQNDRRYQVRQFVEKPAQGTAPSNLAIMGRYVLTPEIFMFLENQQTGAGGEIQLTDAIQRLNEIQRVFAYDFEGTRYDVGEKFGFIKTTIEMALQYEELREDLIKYMDELLKKEMLYV
>NZ_CP043830.1|WP_149890038.1|4977948_4979760_-|polysaccharide-biosynthesis-protein
MSYPKRLSLLIFLDSFIVLTAVYLSYWFVHPNVLSKIPTTVIISSITLLCSHHFFASIYKLYNKAWEYASVGELKQIFKAITLSIIVTAIVQQIINHDIYVRILAIAWMLHLLLIGGSRFVWRMFRDTYITKDTNKKRALIVGAGSAGTMVVRQLQHNKDADLYPIAFVDDDKNKQKLEIYNVPVVGMTNNIKEIVEDNNIEHIIIAIPSLNRKQINEIFEKCTKTKAKTQIVPMLEDLLDGKVSVNEVRDVQVEDLLGREPVQLDDAGIGEKITGKTILVTGAGGSIGSEICRQVMKYKPAKIVLLGHGENSIYNIEMEMRVTYKDTIEITTEIADVQDRNKIFEIIEKHQPYIVYHAAAHKHVPLMERNPEEAVKNNIFGTKNVAEAADTFKVNTFVMVSTDKAVNPTNVMGATKRFAEMLVQHLAAVSTSTQFVAVRFGNVLGSRGSVIPLFKKQIQKGGPVTVTHPDMIRYFMTIPEASRLVIQAGTLAKGGELFVLDMGDPVKIVDLAKNLITLSGYAIEEIGIEFTGLRPGEKMYEELLNEGEIHPEQIFPKIHIGKAVLMEQSILRQFMNDFEKMSKEDIRERLLEIANSKVAIKS
>NZ_CP043830.1|WP_000144458.1|4988866_4989571_-|ABC-transporter-permease
MTFSMRRVSAIFRKEVQDFKTNSQVLLMASLPIIFAFIFSRFGEGRMGVGIITLMAFLFVAGFVQSMVIAEEKEKHTLRVLMLSPASSVEVLLGKSILTACLTLGICIVNLFILDQFGGNLLLLGFIFLCGTILFIVIGTMIGLLAESVPQTSLIGMPILMTMYLAVQFEPMVENKVIKTMIEYLPTSHIAKAINSLVEGAGFSSISGHVLNVGVWLILSVVACLIVYKKKQMD
>NZ_CP043830.1|WP_000170852.1|4989570_4990413_-|ABC-transporter-ATP-binding-protein
MTLAIEMKDVMKSFNEKTALRNVNIEVKQGEIFGFLGPSGSGKTTTVKILTSQLLHSVGTVRVLGKDITGPSSIDYKRIGILTDNSGLYERLSIYDNLLLFCDLYDCKKERIDEVLAQVNLLDDKKTLVKKLSKGMKQRVTLARAILHKPDILFLDEPTSALDPVNVQNIHKILKDLNKEGTTIFLTTHNMEEAETLCNRIAFLCGGEIVALDTPENLRLQYAKDQIQVVLKDKQKEVVQKDELGAKRISEWMKKGELLSIHSHEPTLGDIFIEVTGRGL
>NZ_CP043830.1|WP_098064415.1|4990592_4991600_-|LytTR-family-transcriptional-regulator-DNA-binding-domain-containing-protein
MALLELKQLGKTNQLPAIELEVEKGQCVVLQCNNHTAKVLHRIIIGEEEASTGNVLFGGEAIGKKNYSRIGFCFLKDEAYDRLKVKEYFKFLLGLYELKISIEEVVQYVGLLDKLNVKIEKLSFSEKRRLHIGRVMIHNPDLVILEEPEQNVDTESTIIIRKAIMKMKEKGKAIFITSSFLSDALSLTEDVYILNNDGVKKVEIEQEEAEEVDEEKVVQMIPQMKLERIPAKVNDKIILLDPMEIHFIETQNGVTHIHVREGDFVCALTLSELETRLTGFGFFRCHRSYLVNLQRVREVITWTRNSFSLILDDERKSSIPLSKGRMDELKGVIGL
>NZ_CP043830.1|WP_000672621.1|4991827_4992847_-|stage-II-sporulation-protein-D
MKFSKPFFIIVVLLIALVIIVPAALVIPFAKAKIGEEAASKTPPAIESIPAPGKVDTAVQVAVYRDQQKKVETLPVEEYVTGVVASEMNASFEIEALKAQALAARTFVVQRMLSGEKKNNADVVDTVKDQVYKSKEELKKQWGNNYENNLKKIEEAVSKTAGQVLTYEGKPISASFFSTSNGRTENAADYWGNDYPYLKSVDSPWDQASPKFTSEQTFTVADFQKRLGVKVLADGKVGNIKDLTEGKRVKDVAFQGKTLTGKQVREKLDLRSSDFTWKQEGNKIIVTTKGFGHGVGMSQYGANGMAAEGKKYTDIVAHYYKGVEIKTMNDYEGKLMVKK
>NZ_CP043830.1|WP_000411271.1|4993100_4994405_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDASKELNIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYLDFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVEKLYGGNHSIIPDRIEAGTFMVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQADGTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVGATDLRAAAALILAGLVSEGYTRVTELKHLDRGYVDFHKKLAALGATIERVNEKVEEVKEQEVSDLHA
>NZ_CP043830.1|WP_079519735.1|4994444_4995155_-|YwmB-family-TATA-box-binding-protein
MKLKLKAILIVALSVVFFLVGYREMKPISDEQKMENMIKALEKNDAKMEKWSWLARETKTISNIHTFQKLLNDVKGKANIQKWDLEQSPDGYKATSYKKFASYEERVVVTWSKENTKENTFIIFEVSGAKWDPKHVQKMNKIFNEKPIIYTCVQGVLNDKIEGVLQNKTNQVLKDLSARAIEQVEERAFVSVSAYNKKWDDALSTNREKINVQIAIRSTNNKDTIVVGTPIITSEY
>NZ_CP043830.1|WP_000057885.1|4995200_4995437_-|DUF1146-domain-containing-protein
MAQLLGQQALIAIVSHLLFITITWWALQGIHIERLMKAGKVLQTRVLLILITIAIGTSVSNFFLDYLGYSKSLTYLVK
>NZ_CP043830.1|WP_000366977.1|4995650_4997171_-|NADH-quinone-oxidoreductase-subunit-NuoN
MDMDTLLSLSWHLMLPEFIILGFAILLSIGDLFFKLNHRYVALSAIAAVILAIVSLITLYGEPAGDILNGSFVLDGFSKGFKTLLLGGAALILCTAMSDDKKNPIEDKGEYYYLFLMALLGAMFMASSVDFITLFVGLELLSLSSYVLVGIRKRNRASNEAAMKYVINGGIGTAITLFGMSYLYGITGSTNIVDMQKVFTGELTSGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYEGAATPVTAFLGTISKIAGFLLIIRLFLMIFASVSVQGDMQSLYGRMSIYIAVLASITMIIGNVVALKQYNVKRLFAYSGIAHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIHGLILQSDKENITIFTGLYNRSPFTAIVMTIFILSLAGIPGTAGFIGKINIFLGALHVEPAHYVLASIMMGTTVISFVYYFRILQQMFFRTGEVEEKIRLPLNIKVVMSLCAISIVILGIMPMIGYNFFYEYFPLMKDFFFLGNVVQ
>NZ_CP043830.1|WP_000998954.1|4997172_4998675_-|NADH-quinone-oxidoreductase-subunit-M
MNDLLLTFFIFSPLLGILLLVLTPKKESRTVRALGLFGTALPFGIATVLACTYASGKSLSLFDEKVKWIKFGDFAAVDKRWFSIYYELGIDGLSLVMMVLTALLAMLAAIAAFSIKRNLKAFYMLLLMLEIGMLGVFAAKNLMLFFIFFEITLPPMFLLIGKWGKLSSEKAAYSYLIYNGIGSAILLIVFSILFAKTGTTNIAELKEILTGVSAGGGQIVPSSIQLGVFIAIMIAFAIKLPIFPLHRWMVNVHIEAHPAVVMLHAGVLLKIGAYGMIRFGKGLFPEYFREFATLIAILGVINLLYGAFLALIQTDFRKVLAYSSISHMGIVLMGLAALNAPGTQGALFQVVSHGLIAALLFFLLGVIEQRFGTSDITALGGLAKSVPILSGFFLAGGMASLGLPGMSGFVSEFLAFLGLFQGEPVIAAVGVLGIILTAVYVLRATLQVTFGKKEWEAKTDIHGWEYVPVLLLIFCIIAIGVMPEILGDPLQNTLKTLGVK
>NZ_CP043830.1|WP_098009789.1|4998671_5000534_-|NADH-quinone-oxidoreductase-subunit-L
MIDYAWLIPLFPLVSFFLLIMFGKKIREGSSVLSIFFVSLSFILAVLVLIERFSKVTVKHKWVWLRTGDIDISFGFEVTALGALMLFIVTLVSLLVHVYSKGYMKGDARLPTFYAYLGLFTFAMLGLVISTNLLQLYIFWELVGLGSFLLIGFYFFKEEAKAAAKKAFIMTRIGDVGLFIGMILIFWHAGSFEYEAIFRAIHTGDLSPTMITITAILIFIGAMGKSGQFPLHTWLPDAMEGPTPVSALIHAATMVAAGVYLVATMFPLFSASAVAMQTVAIVGAFTAIFAASIGLVQTDIKRVLAYSTVSQLGYMMLALGSAGYVAGIFHLTTHAFFKALLFLAAGSVIHAVHTQNINKMGGLQKKMKVTGTLFLIGTLAISGVPLLSGFFSKDEILAATWMSGNYFLFVLAVFAAFLTAFYMFRLYFLVFTGEAKTKEEVHDSPRIMTYPMIVLGVLAVVAGYINTPWFGTFLGDWLTKDIQFKVEEAHGPVWIMIVATLVSFGGIALAYFIYGKKTISKNWAGGERSFLHKLLKEKYYVDELYNMTVIPITKGIAHVLRLFEVYVVEGIAVLIASLVKGVSGTLSRLQNGNVQVYGTVTAVSLAVLIIILLYTGGDLR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP043830_2	2.1\|3517873\|47\|NZ_CP043830\|CRT	3517873-3517919	47	NZ_CP043830.1	3517828-3517874	0	1.0
NZ_CP043830_2	2.2\|3517963\|47\|NZ_CP043830\|CRT	3517963-3518009	47	NZ_CP043830.1	3517828-3517874	2	0.957
NZ_CP043830_2	2.3\|3518053\|47\|NZ_CP043830\|CRT	3518053-3518099	47	NZ_CP043830.1	3517828-3517874	2	0.957
NZ_CP043830_2	2.4\|3518143\|47\|NZ_CP043830\|CRT	3518143-3518189	47	NZ_CP043830.1	3517828-3517874	2	0.957
NZ_CP043830_2	2.5\|3518233\|47\|NZ_CP043830\|CRT	3518233-3518279	47	NZ_CP043830.1	3517828-3517874	2	0.957
NZ_CP043830_2	2.16\|3519115\|29\|NZ_CP043830\|CRT	3519115-3519143	29	NZ_CP043830.1	3519349-3519377	2	0.931

1. spacer 2.1|3517873|47|NZ_CP043830|CRT matches to position: 3517828-3517874, mismatch: 0, identity: 1.0

acctcgaggtaacacgggcgctactggtgctactgggcctactggac	CRISPR spacer
acctcgaggtaacacgggcgctactggtgctactgggcctactggac	Protospacer
***********************************************

2. spacer 2.2|3517963|47|NZ_CP043830|CRT matches to position: 3517828-3517874, mismatch: 2, identity: 0.957

acctcgaggtaacacgggcgctaccggtgctactggacctactggac	CRISPR spacer
acctcgaggtaacacgggcgctactggtgctactgggcctactggac	Protospacer
************************.***********.**********

3. spacer 2.3|3518053|47|NZ_CP043830|CRT matches to position: 3517828-3517874, mismatch: 2, identity: 0.957

acctcgaggtaacacgggcgctaccggtgctactggacctactggac	CRISPR spacer
acctcgaggtaacacgggcgctactggtgctactgggcctactggac	Protospacer
************************.***********.**********

4. spacer 2.4|3518143|47|NZ_CP043830|CRT matches to position: 3517828-3517874, mismatch: 2, identity: 0.957

acctcgaggtaacacgggcgctaccggtgctactggacctactggac	CRISPR spacer
acctcgaggtaacacgggcgctactggtgctactgggcctactggac	Protospacer
************************.***********.**********

5. spacer 2.5|3518233|47|NZ_CP043830|CRT matches to position: 3517828-3517874, mismatch: 2, identity: 0.957

acctcgaggtaacacgggcgctaccggtgctactggacctactggac	CRISPR spacer
acctcgaggtaacacgggcgctactggtgctactgggcctactggac	Protospacer
************************.***********.**********

6. spacer 2.16|3519115|29|NZ_CP043830|CRT matches to position: 3519349-3519377, mismatch: 2, identity: 0.931

taacacaggggctactggggctactgggg	CRISPR spacer
taacacaggtgctactggtgctactgggg	Protospacer
********* ******** **********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP043830_2	2.16\|3519115\|29\|NZ_CP043830\|CRT	3519115-3519143	29	NC_014025	Bacillus megaterium QM B1551 plasmid pBM500, complete sequence	53306-53334	4	0.862
NZ_CP043830_2	2.16\|3519115\|29\|NZ_CP043830\|CRT	3519115-3519143	29	NC_031927	Synechococcus phage S-CAM7 isolate 0910CC49, complete genome	16726-16754	7	0.759
NZ_CP043830_2	2.16\|3519115\|29\|NZ_CP043830\|CRT	3519115-3519143	29	KU686213	Synechococcus phage S-CAM7 isolate 0910SB42, complete genome	17644-17672	7	0.759
NZ_CP043830_2	2.16\|3519115\|29\|NZ_CP043830\|CRT	3519115-3519143	29	MK521907	Klebsiella phage vB_KpnS_FZ41, complete genome	71438-71466	7	0.759
NZ_CP043830_2	2.16\|3519115\|29\|NZ_CP043830\|CRT	3519115-3519143	29	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	9177-9205	8	0.724
NZ_CP043830_2	2.16\|3519115\|29\|NZ_CP043830\|CRT	3519115-3519143	29	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	9330-9358	8	0.724
NZ_CP043830_2	2.16\|3519115\|29\|NZ_CP043830\|CRT	3519115-3519143	29	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	21356-21384	8	0.724
NZ_CP043830_2	2.16\|3519115\|29\|NZ_CP043830\|CRT	3519115-3519143	29	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	21509-21537	8	0.724
NZ_CP043830_2	2.16\|3519115\|29\|NZ_CP043830\|CRT	3519115-3519143	29	NC_011771	Bacillus cereus AH820 plasmid pAH820_10, complete sequence	10707-10735	8	0.724
NZ_CP043830_2	2.16\|3519115\|29\|NZ_CP043830\|CRT	3519115-3519143	29	NC_011771	Bacillus cereus AH820 plasmid pAH820_10, complete sequence	10788-10816	8	0.724
NZ_CP043830_2	2.16\|3519115\|29\|NZ_CP043830\|CRT	3519115-3519143	29	NZ_CP009336	Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence	104027-104055	8	0.724
NZ_CP043830_3	3.2\|4987923\|34\|NZ_CP043830\|CRISPRCasFinder	4987923-4987956	34	NZ_CP014851	Bacillus thuringiensis strain HD12 plasmid pHD120112, complete sequence	100650-100683	8	0.765
NZ_CP043830_2	2.9\|3518593\|38\|NZ_CP043830\|CRT	3518593-3518630	38	MT380195	Klebsiella phage KP_LZD_B01, complete genome	78583-78620	9	0.763
NZ_CP043830_2	2.9\|3518593\|38\|NZ_CP043830\|CRT	3518593-3518630	38	KX845404	Klebsiella phage vB_Kpn_IME260, complete genome	83088-83125	9	0.763
NZ_CP043830_2	2.16\|3519115\|29\|NZ_CP043830\|CRT	3519115-3519143	29	NC_014025	Bacillus megaterium QM B1551 plasmid pBM500, complete sequence	53315-53343	9	0.69
NZ_CP043830_3	3.2\|4987923\|34\|NZ_CP043830\|CRISPRCasFinder	4987923-4987956	34	MT811961	Vibrio phage vB_pir03, complete genome	153057-153090	10	0.706
NZ_CP043830_3	3.2\|4987923\|34\|NZ_CP043830\|CRISPRCasFinder	4987923-4987956	34	MN812210	Flavobacterium phage vB_FspS_hemulen9-1, complete genome	22854-22887	10	0.706
NZ_CP043830_3	3.2\|4987923\|34\|NZ_CP043830\|CRISPRCasFinder	4987923-4987956	34	MN812215	Flavobacterium phage vB_FspS_lillamy9-4, complete genome	22191-22224	10	0.706
NZ_CP043830_3	3.2\|4987923\|34\|NZ_CP043830\|CRISPRCasFinder	4987923-4987956	34	MN812216	Flavobacterium phage vB_FspS_lillamy9-5, complete genome	22191-22224	10	0.706
NZ_CP043830_3	3.2\|4987923\|34\|NZ_CP043830\|CRISPRCasFinder	4987923-4987956	34	NC_048835	Flavobacterium phage vB_FspS_lillamy9-1, complete genome	22191-22224	10	0.706
NZ_CP043830_3	3.2\|4987923\|34\|NZ_CP043830\|CRISPRCasFinder	4987923-4987956	34	MN812213	Flavobacterium phage vB_FspS_lillamy9-2, complete genome	22191-22224	10	0.706
NZ_CP043830_3	3.2\|4987923\|34\|NZ_CP043830\|CRISPRCasFinder	4987923-4987956	34	MN812230	Flavobacterium phage vB_FspS_sniff9-2, complete genome	21831-21864	10	0.706
NZ_CP043830_3	3.2\|4987923\|34\|NZ_CP043830\|CRISPRCasFinder	4987923-4987956	34	MN812209	Flavobacterium phage vB_FspS_hemulen6-2, complete genome	22983-23016	10	0.706
NZ_CP043830_3	3.2\|4987923\|34\|NZ_CP043830\|CRISPRCasFinder	4987923-4987956	34	MN812218	Flavobacterium phage vB_FspS_lillamy9-7, complete genome	21454-21487	10	0.706
NZ_CP043830_3	3.2\|4987923\|34\|NZ_CP043830\|CRISPRCasFinder	4987923-4987956	34	MN812233	Flavobacterium phage vB_FspS_snork9-1, complete genome	22007-22040	10	0.706
NZ_CP043830_3	3.2\|4987923\|34\|NZ_CP043830\|CRISPRCasFinder	4987923-4987956	34	MN812219	Flavobacterium phage vB_FspS_morran9-1, complete genome	22308-22341	10	0.706
NZ_CP043830_3	3.2\|4987923\|34\|NZ_CP043830\|CRISPRCasFinder	4987923-4987956	34	MN812217	Flavobacterium phage vB_FspS_lillamy9-6, complete genome	21930-21963	10	0.706
NZ_CP043830_3	3.2\|4987923\|34\|NZ_CP043830\|CRISPRCasFinder	4987923-4987956	34	NC_048840	Flavobacterium phage vB_FspS_snork6-1, complete genome	22137-22170	10	0.706
NZ_CP043830_3	3.2\|4987923\|34\|NZ_CP043830\|CRISPRCasFinder	4987923-4987956	34	NC_048839	Flavobacterium phage vB_FspS_sniff9-1, complete genome	22057-22090	10	0.706
NZ_CP043830_3	3.2\|4987923\|34\|NZ_CP043830\|CRISPRCasFinder	4987923-4987956	34	NC_048842	Flavobacterium phage vB_FspS_stinky9-1, complete genome	21673-21706	10	0.706
NZ_CP043830_3	3.2\|4987923\|34\|NZ_CP043830\|CRISPRCasFinder	4987923-4987956	34	MN812232	Flavobacterium phage vB_FspS_snork6-2, complete genome	21655-21688	10	0.706
NZ_CP043830_3	3.2\|4987923\|34\|NZ_CP043830\|CRISPRCasFinder	4987923-4987956	34	MN812208	Flavobacterium phage vB_FspS_hemulen6-1, complete genome	22983-23016	10	0.706

1. spacer 2.16|3519115|29|NZ_CP043830|CRT matches to NC_014025 (Bacillus megaterium QM B1551 plasmid pBM500, complete sequence) position: , mismatch: 4, identity: 0.862

taacacaggggctactggggctactgggg	CRISPR spacer
agtcactggggctactggggctactgggg	Protospacer
 . *** **********************

2. spacer 2.16|3519115|29|NZ_CP043830|CRT matches to NC_031927 (Synechococcus phage S-CAM7 isolate 0910CC49, complete genome) position: , mismatch: 7, identity: 0.759

taacacaggggctactggggctactgggg	CRISPR spacer
tgctactggggctactggagctactggaa	Protospacer
*. .** ***********.********..

3. spacer 2.16|3519115|29|NZ_CP043830|CRT matches to KU686213 (Synechococcus phage S-CAM7 isolate 0910SB42, complete genome) position: , mismatch: 7, identity: 0.759

taacacaggggctactggggctactgggg	CRISPR spacer
tgctactggggctactggagctactggaa	Protospacer
*. .** ***********.********..

4. spacer 2.16|3519115|29|NZ_CP043830|CRT matches to MK521907 (Klebsiella phage vB_KpnS_FZ41, complete genome) position: , mismatch: 7, identity: 0.759

taacacaggggctactggggctactgggg	CRISPR spacer
cgagaaaggggctactggtgctactggtc	Protospacer
..* * ************ ********

5. spacer 2.16|3519115|29|NZ_CP043830|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.724

taacacaggggctactggggctactgggg	CRISPR spacer
agctacaggagctactggagctactggac	Protospacer
 . .*****.********.********.

6. spacer 2.16|3519115|29|NZ_CP043830|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.724

taacacaggggctactggggctactgggg	CRISPR spacer
agctacaggagctactggagctactggac	Protospacer
 . .*****.********.********.

7. spacer 2.16|3519115|29|NZ_CP043830|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.724

taacacaggggctactggggctactgggg	CRISPR spacer
agctacaggagctactggagctactggac	Protospacer
 . .*****.********.********.

8. spacer 2.16|3519115|29|NZ_CP043830|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.724

taacacaggggctactggggctactgggg	CRISPR spacer
agctacaggagctactggagctactggac	Protospacer
 . .*****.********.********.

9. spacer 2.16|3519115|29|NZ_CP043830|CRT matches to NC_011771 (Bacillus cereus AH820 plasmid pAH820_10, complete sequence) position: , mismatch: 8, identity: 0.724

taacacaggggctactggggctactgggg	CRISPR spacer
atctacaggagctactggagctactggac	Protospacer
   .*****.********.********.

10. spacer 2.16|3519115|29|NZ_CP043830|CRT matches to NC_011771 (Bacillus cereus AH820 plasmid pAH820_10, complete sequence) position: , mismatch: 8, identity: 0.724

taacacaggggctactggggctactgggg	CRISPR spacer
agctacaggagctactggagctactggac	Protospacer
 . .*****.********.********.

11. spacer 2.16|3519115|29|NZ_CP043830|CRT matches to NZ_CP009336 (Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.724

taacacaggggctactggggctactgggg	CRISPR spacer
attaacagggcctactgggcctactggac	Protospacer
    ****** ******** *******.

12. spacer 3.2|4987923|34|NZ_CP043830|CRISPRCasFinder matches to NZ_CP014851 (Bacillus thuringiensis strain HD12 plasmid pHD120112, complete sequence) position: , mismatch: 8, identity: 0.765

cttatcttctgttttactttctggtttcgtgctc	CRISPR spacer
tttatcttcttttttattttctggtttattttcc	Protospacer
.********* *****.**********  * ..*

13. spacer 2.9|3518593|38|NZ_CP043830|CRT matches to MT380195 (Klebsiella phage KP_LZD_B01, complete genome) position: , mismatch: 9, identity: 0.763

taacactggcgctactggacctcaaggtgttcaaggta	CRISPR spacer
taacactggtgctactggtcctcaaggtaacaaggggg	Protospacer
*********.******** *********. . *.** .

14. spacer 2.9|3518593|38|NZ_CP043830|CRT matches to KX845404 (Klebsiella phage vB_Kpn_IME260, complete genome) position: , mismatch: 9, identity: 0.763

taacactggcgctactggacctcaaggtgttcaaggta	CRISPR spacer
taacactggtgctactggtcctcaaggtaacaaggggg	Protospacer
*********.******** *********. . *.** .

15. spacer 2.16|3519115|29|NZ_CP043830|CRT matches to NC_014025 (Bacillus megaterium QM B1551 plasmid pBM500, complete sequence) position: , mismatch: 9, identity: 0.69

taacacaggggctactggggctactgggg---------	CRISPR spacer
---------ggctactggggctactggggctaccggtc	Protospacer
         ********************

16. spacer 3.2|4987923|34|NZ_CP043830|CRISPRCasFinder matches to MT811961 (Vibrio phage vB_pir03, complete genome) position: , mismatch: 10, identity: 0.706

cttatcttctgttttactttctggtttcgtgctc	CRISPR spacer
tttatcttctgttttagtttgtggttgaattagt	Protospacer
.*************** *** *****  .*   .

17. spacer 3.2|4987923|34|NZ_CP043830|CRISPRCasFinder matches to MN812210 (Flavobacterium phage vB_FspS_hemulen9-1, complete genome) position: , mismatch: 10, identity: 0.706

cttatcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.. ***********.********* **   *.

18. spacer 3.2|4987923|34|NZ_CP043830|CRISPRCasFinder matches to MN812215 (Flavobacterium phage vB_FspS_lillamy9-4, complete genome) position: , mismatch: 10, identity: 0.706

cttatcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.. ***********.********* **   *.

19. spacer 3.2|4987923|34|NZ_CP043830|CRISPRCasFinder matches to MN812216 (Flavobacterium phage vB_FspS_lillamy9-5, complete genome) position: , mismatch: 10, identity: 0.706

cttatcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.. ***********.********* **   *.

20. spacer 3.2|4987923|34|NZ_CP043830|CRISPRCasFinder matches to NC_048835 (Flavobacterium phage vB_FspS_lillamy9-1, complete genome) position: , mismatch: 10, identity: 0.706

cttatcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.. ***********.********* **   *.

21. spacer 3.2|4987923|34|NZ_CP043830|CRISPRCasFinder matches to MN812213 (Flavobacterium phage vB_FspS_lillamy9-2, complete genome) position: , mismatch: 10, identity: 0.706

cttatcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.. ***********.********* **   *.

22. spacer 3.2|4987923|34|NZ_CP043830|CRISPRCasFinder matches to MN812230 (Flavobacterium phage vB_FspS_sniff9-2, complete genome) position: , mismatch: 10, identity: 0.706

cttatcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.. ***********.********* **   *.

23. spacer 3.2|4987923|34|NZ_CP043830|CRISPRCasFinder matches to MN812209 (Flavobacterium phage vB_FspS_hemulen6-2, complete genome) position: , mismatch: 10, identity: 0.706

cttatcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.. ***********.********* **   *.

24. spacer 3.2|4987923|34|NZ_CP043830|CRISPRCasFinder matches to MN812218 (Flavobacterium phage vB_FspS_lillamy9-7, complete genome) position: , mismatch: 10, identity: 0.706

cttatcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.. ***********.********* **   *.

25. spacer 3.2|4987923|34|NZ_CP043830|CRISPRCasFinder matches to MN812233 (Flavobacterium phage vB_FspS_snork9-1, complete genome) position: , mismatch: 10, identity: 0.706

cttatcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.. ***********.********* **   *.

26. spacer 3.2|4987923|34|NZ_CP043830|CRISPRCasFinder matches to MN812219 (Flavobacterium phage vB_FspS_morran9-1, complete genome) position: , mismatch: 10, identity: 0.706

cttatcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.. ***********.********* **   *.

27. spacer 3.2|4987923|34|NZ_CP043830|CRISPRCasFinder matches to MN812217 (Flavobacterium phage vB_FspS_lillamy9-6, complete genome) position: , mismatch: 10, identity: 0.706

cttatcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.. ***********.********* **   *.

28. spacer 3.2|4987923|34|NZ_CP043830|CRISPRCasFinder matches to NC_048840 (Flavobacterium phage vB_FspS_snork6-1, complete genome) position: , mismatch: 10, identity: 0.706

cttatcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.. ***********.********* **   *.

29. spacer 3.2|4987923|34|NZ_CP043830|CRISPRCasFinder matches to NC_048839 (Flavobacterium phage vB_FspS_sniff9-1, complete genome) position: , mismatch: 10, identity: 0.706

cttatcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.. ***********.********* **   *.

30. spacer 3.2|4987923|34|NZ_CP043830|CRISPRCasFinder matches to NC_048842 (Flavobacterium phage vB_FspS_stinky9-1, complete genome) position: , mismatch: 10, identity: 0.706

cttatcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.. ***********.********* **   *.

31. spacer 3.2|4987923|34|NZ_CP043830|CRISPRCasFinder matches to MN812232 (Flavobacterium phage vB_FspS_snork6-2, complete genome) position: , mismatch: 10, identity: 0.706

cttatcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.. ***********.********* **   *.

32. spacer 3.2|4987923|34|NZ_CP043830|CRISPRCasFinder matches to MN812208 (Flavobacterium phage vB_FspS_hemulen6-1, complete genome) position: , mismatch: 10, identity: 0.706

cttatcttctgttttactttctggtttcgtgctc	CRISPR spacer
ttcggcttctgttttattttctggttgcgatatt	Protospacer
.*.. ***********.********* **   *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

318865 : 327240

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000610752.1\|318865_320173_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.9e-21	25.5
WP_061529454.1\|320261_320981_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	2.3e-49	44.8
WP_000278820.1\|320973_321228_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666769.1\|321224_321908_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_000055552.1\|321891_324111_+	phosphoribosylformylglycinamidine synthase II	A6N228	Microbacterium_phage	2.8e-162	41.3
WP_000879031.1\|324095_325511_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	7.3e-55	35.4
WP_097927524.1\|325615_326656_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	1.2e-67	45.6
WP_000088570.1\|326652_327240_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	5.9e-27	36.4

DBSCAN-SWA_2

1874291 : 1883129

Bacillus_phage(71.43%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000755505.1\|1874291_1875569_+	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	2.2e-10	37.5
WP_001194291.1\|1875665_1876430_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_000453894.1\|1876670_1878431_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	6.1e-269	96.7
WP_000612405.1\|1878516_1879194_+	response regulator transcription factor	W8CYM9	Bacillus_phage	3.7e-121	97.3
WP_001231633.1\|1879190_1880264_+	HAMP domain-containing sensor histidine kinase	W8CYF6	Bacillus_phage	6.5e-189	98.0
WP_000818985.1\|1880433_1881153_+	3-ketoacyl-ACP reductase	W8CYX9	Bacillus_phage	5.9e-61	100.0
WP_002106170.1\|1881302_1881722_+	class I SAM-dependent methyltransferase	W8CYT3	Bacillus_phage	4.0e-70	96.4
WP_001258518.1\|1882256_1883129_+	aminoglycoside 6-adenylyltransferase	A0A1X9I6F2	Streptococcus_phage	4.3e-66	45.2

DBSCAN-SWA_3

3497717 : 3509359

Bacillus_phage(50.0%)

bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000222377.1\|3497717_3499544_-	polysaccharide biosynthesis protein	A0A1V0SAI8	Catovirus	5.9e-25	30.3
WP_000323603.1\|3499839_3500502_-	CpsD/CapB family tyrosine-protein kinase	NA	NA	NA	NA
WP_001031071.1\|3500450_3501191_-	LPS biosynthesis protein	NA	NA	NA	NA
WP_073990767.1\|3501533_3501764_-\|bacteriocin	bacteriocin biosynthesis protein	A0A1B1P7Q9	Bacillus_phage	1.0e-19	67.1
WP_098908389.1\|3501935_3502931_-	N-acetylmuramoyl-L-alanine amidase	A0A218KCJ1	Bacillus_phage	2.0e-83	50.4
WP_000190134.1\|3502998_3503820_-	M23 family metallopeptidase	A0A218KCJ1	Bacillus_phage	2.1e-22	41.1
WP_000025071.1\|3504074_3505043_-	lysozyme family protein	A0A223LKM8	Bacillus_phage	1.1e-30	42.2
WP_000464429.1\|3505281_3505668_-	hypothetical protein	A0A288WG73	Bacillus_phage	6.4e-46	69.8
WP_000511428.1\|3506065_3506935_-	DnaD domain protein	A0A2H4J394	uncultured_Caudovirales_phage	1.2e-95	58.6
WP_001189063.1\|3507083_3507278_-	hypothetical protein	A0A2H4J4V8	uncultured_Caudovirales_phage	2.4e-17	71.0
WP_000283429.1\|3508233_3508497_-	hypothetical protein	A6M975	Geobacillus_virus	2.8e-13	60.0
WP_000409433.1\|3508699_3509359_+	helix-turn-helix domain-containing protein	A0A2H4J441	uncultured_Caudovirales_phage	1.0e-35	41.9

DBSCAN-SWA_4

4302963 : 4310636

Staphylococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_016109160.1\|4302963_4303887_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.3e-46	43.1
WP_000183219.1\|4304013_4304949_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	6.3e-23	26.3
WP_053445942.1\|4304950_4305643_-	response regulator transcription factor	B5LWA6	Feldmannia_species_virus	1.4e-06	28.8
WP_001293579.1\|4305811_4305985_+	hypothetical protein	NA	NA	NA	NA
WP_001014310.1\|4305985_4306180_+	YwbE family protein	NA	NA	NA	NA
WP_001255942.1\|4306219_4307419_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	1.9e-72	41.3
WP_000587821.1\|4307705_4308029_+	heme oxygenase	NA	NA	NA	NA
WP_002093213.1\|4308095_4308860_-	class B sortase	NA	NA	NA	NA
WP_000403763.1\|4308892_4309663_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	9.9e-14	28.6
WP_001036848.1\|4309652_4310636_-	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	1.1e-17	27.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP043834

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

26553 : 31921

Bacillus_phage(71.43%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000160670.1\|26553_27666_-	helix-turn-helix domain-containing protein	A0A286QQB7	Streptococcus_phage	7.4e-79	45.2
WP_000762741.1\|27677_28076_-\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	1.5e-50	68.2
WP_000147171.1\|28371_28830_-	DUF559 domain-containing protein	NA	NA	NA	NA
WP_000466112.1\|29208_29430_+	helix-turn-helix transcriptional regulator	A0A0S2GLH4	Bacillus_phage	1.1e-10	49.3
WP_002105922.1\|29458_30112_-	replication-relaxation family protein	A0A1B1P7T2	Bacillus_phage	1.4e-77	64.4
WP_149890238.1\|30095_31259_-	DUF87 domain-containing protein	W8CYG2	Bacillus_phage	3.5e-156	70.5
WP_000934652.1\|31271_31595_-	hypothetical protein	A0A1B1P7T1	Bacillus_phage	4.8e-31	65.4
WP_149890239.1\|31588_31921_-	hypothetical protein	A0A1B1P7T3	Bacillus_phage	1.8e-33	69.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP043831

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP043830

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP043834

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection