CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP042244	Crassaminicella sp. SY095 plasmid pCT01, complete sequence	0 crisprs	NA	0	0	1	0
NZ_CP042243	Crassaminicella sp. SY095 chromosome, complete genome	2 crisprs	WYL,cas6,cas8b2,cas7,cas5,cas3,cas4,cas2,csa3,cas14j,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,DinG,csx1,DEDDh,RT	0	10	6	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

880 : 34780

Clostridium_phage(56.67%)

head,tail,integrase,portal,protease,capsid,plate,terminase

attL 6461:6475|attR 30156:30170

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_148810887.1\|880_1258_+	HNH endonuclease	A0A0A7RUV1	Clostridium_phage	1.2e-25	48.0
WP_148810888.1\|1259_1439_+	hypothetical protein	Q8SBK6	Clostridium_phage	1.6e-07	44.8
WP_148810889.1\|1551_2013_+\|terminase	phage terminase small subunit P27 family	A0A0A7RUQ4	Clostridium_phage	2.8e-56	74.5
WP_148810890.1\|2009_3704_+\|terminase	terminase large subunit	A0A0A7RUM0	Clostridium_phage	1.9e-198	61.6
WP_148810891.1\|3716_4946_+\|portal	phage portal protein	A0A0A7S1E7	Clostridium_phage	4.8e-196	80.7
WP_148810892.1\|4945_5680_+\|protease	Clp protease ClpP	A0A0A7RWX3	Clostridium_phage	4.3e-67	58.2
WP_148810893.1\|5691_6795_+\|capsid	phage major capsid protein	A0A0A7RUV5	Clostridium_phage	1.8e-130	74.4
6461:6475	attL	NA	NA	NA	NA
WP_168198407.1\|6839_6992_+	hypothetical protein	A6M952	Geobacillus_virus	1.7e-07	60.0
WP_148810894.1\|7009_7297_+\|head,tail	phage gp6-like head-tail connector protein	A0A2H4J6E5	uncultured_Caudovirales_phage	1.6e-17	54.5
WP_148810895.1\|7293_7623_+\|head	phage head closure protein	NA	NA	NA	NA
WP_148810896.1\|7622_8078_+	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_148810897.1\|8082_8505_+	hypothetical protein	NA	NA	NA	NA
WP_148810898.1\|8508_9564_+\|tail	phage tail sheath protein	A0A0A8WJL8	Clostridium_phage	1.7e-80	47.3
WP_148810899.1\|10023_10416_+	hypothetical protein	NA	NA	NA	NA
WP_148810900.1\|10609_12589_+	hypothetical protein	A0A0E3Y5G6	Fusobacterium_phage	4.0e-35	37.5
WP_148810901.1\|12599_13013_+\|portal	phage portal protein	NA	NA	NA	NA
WP_148810902.1\|13016_13982_+	hypothetical protein	A0A0A7RTP6	Clostridium_phage	5.7e-19	28.9
WP_148810903.1\|13981_14398_+	DUF2577 family protein	NA	NA	NA	NA
WP_148810904.1\|14397_14844_+	DUF2634 domain-containing protein	A0A0A7RUS1	Clostridium_phage	4.0e-07	29.6
WP_148810905.1\|14844_15888_+\|plate	baseplate J/gp47 family protein	A0A0A7RUN3	Clostridium_phage	7.5e-73	45.6
WP_148810939.1\|15892_16414_+	DUF2313 domain-containing protein	S6BFJ0	Thermus_phage	5.1e-30	42.0
WP_168198408.1\|16414_17359_+	hypothetical protein	NA	NA	NA	NA
WP_148810906.1\|17373_17691_+	hypothetical protein	NA	NA	NA	NA
WP_148810907.1\|17744_18296_+	N-acetylmuramoyl-L-alanine amidase	M9Q1I7	Clostridium_phage	7.3e-27	44.0
WP_148809720.1\|18304_18523_+	hypothetical protein	Q0SPG4	Clostridium_phage	2.1e-06	41.7
WP_148810908.1\|18527_18734_+	hypothetical protein	NA	NA	NA	NA
WP_148810909.1\|19132_19333_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_168198409.1\|19561_19807_+	sce7726 family protein	A0A0U2RXY7	Escherichia_phage	1.2e-10	47.9
WP_148810911.1\|20259_20955_-	hypothetical protein	NA	NA	NA	NA
WP_148810912.1\|20954_21176_-	hypothetical protein	NA	NA	NA	NA
WP_148810913.1\|21498_21717_+	winged helix-turn-helix transcriptional regulator	A0A1B2APZ1	Phage_Wrath	8.3e-19	65.2
WP_148810914.1\|21998_23171_-\|integrase	tyrosine-type recombinase/integrase	A0A0C5AN64	Paenibacillus_phage	7.5e-106	49.3
WP_148810915.1\|23167_23617_-	ImmA/IrrE family metallo-endopeptidase	I3VYZ2	Thermoanaerobacterium_phage	3.3e-09	33.1
WP_148810916.1\|23647_24088_-	helix-turn-helix domain-containing protein	A0A0A7RTK4	Clostridium_phage	9.9e-19	42.0
WP_148810917.1\|24322_24535_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_148810918.1\|24566_24770_+	helix-turn-helix domain-containing protein	A0A0C5AN65	Paenibacillus_phage	2.0e-11	52.5
WP_148810919.1\|24766_25468_+	hypothetical protein	A0A288WFT2	Bacillus_phage	3.3e-32	42.1
WP_168198415.1\|25520_25769_+	ubiquitin	NA	NA	NA	NA
WP_148810921.1\|25783_25966_+	hypothetical protein	NA	NA	NA	NA
WP_168198410.1\|26003_26168_+	hypothetical protein	NA	NA	NA	NA
WP_148810922.1\|26209_26542_+	zinc-ribbon domain-containing protein	NA	NA	NA	NA
WP_148810923.1\|26546_26738_-	hypothetical protein	NA	NA	NA	NA
WP_168198411.1\|26805_26970_+	hypothetical protein	NA	NA	NA	NA
WP_148810924.1\|27096_27282_+	hypothetical protein	NA	NA	NA	NA
WP_148810925.1\|27349_27490_+	Spo0E family sporulation regulatory protein-aspartic acid phosphatase	NA	NA	NA	NA
WP_148810926.1\|27486_27699_+	hypothetical protein	NA	NA	NA	NA
WP_148810927.1\|27938_28364_+	hypothetical protein	J9QD21	Clostridium_phage	1.1e-33	56.9
WP_168198412.1\|28524_29430_+	DUF4373 domain-containing protein	S4TZS9	uncultured_phage	1.8e-19	47.8
WP_148810929.1\|29422_29977_+	hypothetical protein	NA	NA	NA	NA
WP_148810930.1\|30004_30217_+	hypothetical protein	NA	NA	NA	NA
30156:30170	attR	NA	NA	NA	NA
WP_148810931.1\|30213_30804_+	hypothetical protein	NA	NA	NA	NA
WP_168198413.1\|30796_30952_+	hypothetical protein	NA	NA	NA	NA
WP_148810932.1\|30914_31337_+	RusA family crossover junction endodeoxyribonuclease	NA	NA	NA	NA
WP_148810933.1\|31329_31974_+	hypothetical protein	U5U4M2	Lactobacillus_phage	7.2e-34	36.0
WP_148810934.1\|32180_33113_+	nucleoid-associated protein	J9QE81	Clostridium_phage	2.8e-39	33.4
WP_148810940.1\|33784_34447_+	phosphoadenosine phosphosulfate reductase family protein	Q24LD4	Clostridium_phage	1.5e-31	36.3
WP_148809881.1\|34522_34780_+	hypothetical protein	A0A1B1P779	Bacillus_phage	5.4e-09	37.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP042243

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP042243_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042243_1

179464-180590

Unclear

I-A

Consensus_repeat	Method
ATTTATCTTAACTATGTGGTATGTAAAT	PILER-CR
ATTTATCTTAACTATGTGGTATGTAAAT	CRISPRCasFinder
ATTTATCTTAACTATGTGGTATGTAAAT	CRT

17 spacers

cas2,cas4,cas3,cas5,cas7,cas8b2,cas6,WYL

The CRISPR arrays of NZ_CP042243_1

>merge|NZ_CP042243|1|179464-180590|PILER-CR,CRISPRCasFinder,CRT
ATTTATCTTAACTATGTGGTATGTAAATATAGGTTCGGTAAAAATTTTAAATGCAAATGAAAGATTTATCTTAACTATGTGGTATGTAAATTTAAAAAACTCAATGATTTCATCAAGGCTCTCTGACTCATTTATCTTAACTATGTGGTATGTAAATTTAAGCTTGGTAAAGGAGCTAGTATTCTCTTATCAGTATTTATCTTAACTATGTGGTATGTAAATTAAACTTTAAATTTTTCAGCAAAACTGTTCCTACCTATTTATCTTAACTATGTGGTATGTAAATAATAGCTCCCTCAATTCTTTAAGTGTCAATTTATCCATTTATCTTAACTATGTGGTATGTAAATTTTTATCAGCTACTTTTGTAACTGCTTCATTAGCAGATTTATCTTAACTATGTGGTATGTAAATGGTAATTATGAAGTTATTTTAAAACCTGTGAGTACTATTTATCTTAACTATGTGGTATGTAAATTTAAGGAAAATATACAAGATTTAAAAACTGCAAATGATTTATCTTAACTATGTGGTATGTAAATAAAAAATCACCAAGCAGACTATCATCTGTACCGCTGATTTATCTTAACTATGTGGTATGTAAATATTTTAGGTTCAAATTCAATTGTAAATGGAAAATATATTTATCTTAACTATGTGGTATGTAAATTGAAATATAAACGCTATACCTACAAGAAATCCGAATATTTATCTTAACTATGTGGTATGTAAATACTTTTCGAAATGAAAAATTGATTCAACTATTGCATGGGATTTATCTTAACTATGTGGTATGTAAATAGACAAACATTTCTTAGAGAAGCAGCATCCATCCCCGATTTATCTTAACTATGTGGTATGTAAATAATAGAAAATATCTAATCCTATACCACTAAAAATAAGATTTATCTTAACTATGTGGTATGTAAATGCATAGAGCTTAAGCGTATCTTCTAAATTCATGTTAGATTTATCTTAACTATGTGGTATGTAAATTGTGATAGTGTTGAACAATTAAATCATACTTTCTTGATTTATCTTAACTATGTGGTATGTAAATTATTTTCCAGCTTCATATTGACCTAGTTTAACTCTTTCGATTTATCTTAACTATGTGGGAGTTTAAA

>NZ_CP042243|1|1|179464-180523|PILER-CR
ATTTATCTTAACTATGTGGTATGTAAAT	ATAGGTTCGGTAAAAATTTTAAATGCAAATGAAAG
ATTTATCTTAACTATGTGGTATGTAAAT	TTAAAAAACTCAATGATTTCATCAAGGCTCTCTGACTC
ATTTATCTTAACTATGTGGTATGTAAAT	TTAAGCTTGGTAAAGGAGCTAGTATTCTCTTATCAGT
ATTTATCTTAACTATGTGGTATGTAAAT	TAAACTTTAAATTTTTCAGCAAAACTGTTCCTACCT
ATTTATCTTAACTATGTGGTATGTAAAT	AATAGCTCCCTCAATTCTTTAAGTGTCAATTTATCC
ATTTATCTTAACTATGTGGTATGTAAAT	TTTTATCAGCTACTTTTGTAACTGCTTCATTAGCAG
ATTTATCTTAACTATGTGGTATGTAAAT	GGTAATTATGAAGTTATTTTAAAACCTGTGAGTACT
ATTTATCTTAACTATGTGGTATGTAAAT	TTAAGGAAAATATACAAGATTTAAAAACTGCAAATG
ATTTATCTTAACTATGTGGTATGTAAAT	AAAAAATCACCAAGCAGACTATCATCTGTACCGCTG
ATTTATCTTAACTATGTGGTATGTAAAT	ATTTTAGGTTCAAATTCAATTGTAAATGGAAAATAT
ATTTATCTTAACTATGTGGTATGTAAAT	TGAAATATAAACGCTATACCTACAAGAAATCCGAAT
ATTTATCTTAACTATGTGGTATGTAAAT	ACTTTTCGAAATGAAAAATTGATTCAACTATTGCATGGG
ATTTATCTTAACTATGTGGTATGTAAAT	AGACAAACATTTCTTAGAGAAGCAGCATCCATCCCCG
ATTTATCTTAACTATGTGGTATGTAAAT	AATAGAAAATATCTAATCCTATACCACTAAAAATAAG
ATTTATCTTAACTATGTGGTATGTAAAT	GCATAGAGCTTAAGCGTATCTTCTAAATTCATGTTAG
ATTTATCTTAACTATGTGGTATGTAAAT	TGTGATAGTGTTGAACAATTAAATCATACTTTCTTG
ATTTATCTTAACTATGTGGTATGTAAAT

>NZ_CP042243|1|1|179464-180590|CRISPRCasFinder
ATTTATCTTAACTATGTGGTATGTAAAT	ATAGGTTCGGTAAAAATTTTAAATGCAAATGAAAG
ATTTATCTTAACTATGTGGTATGTAAAT	TTAAAAAACTCAATGATTTCATCAAGGCTCTCTGACTC
ATTTATCTTAACTATGTGGTATGTAAAT	TTAAGCTTGGTAAAGGAGCTAGTATTCTCTTATCAGT
ATTTATCTTAACTATGTGGTATGTAAAT	TAAACTTTAAATTTTTCAGCAAAACTGTTCCTACCT
ATTTATCTTAACTATGTGGTATGTAAAT	AATAGCTCCCTCAATTCTTTAAGTGTCAATTTATCC
ATTTATCTTAACTATGTGGTATGTAAAT	TTTTATCAGCTACTTTTGTAACTGCTTCATTAGCAG
ATTTATCTTAACTATGTGGTATGTAAAT	GGTAATTATGAAGTTATTTTAAAACCTGTGAGTACT
ATTTATCTTAACTATGTGGTATGTAAAT	TTAAGGAAAATATACAAGATTTAAAAACTGCAAATG
ATTTATCTTAACTATGTGGTATGTAAAT	AAAAAATCACCAAGCAGACTATCATCTGTACCGCTG
ATTTATCTTAACTATGTGGTATGTAAAT	ATTTTAGGTTCAAATTCAATTGTAAATGGAAAATAT
ATTTATCTTAACTATGTGGTATGTAAAT	TGAAATATAAACGCTATACCTACAAGAAATCCGAAT
ATTTATCTTAACTATGTGGTATGTAAAT	ACTTTTCGAAATGAAAAATTGATTCAACTATTGCATGGG
ATTTATCTTAACTATGTGGTATGTAAAT	AGACAAACATTTCTTAGAGAAGCAGCATCCATCCCCG
ATTTATCTTAACTATGTGGTATGTAAAT	AATAGAAAATATCTAATCCTATACCACTAAAAATAAG
ATTTATCTTAACTATGTGGTATGTAAAT	GCATAGAGCTTAAGCGTATCTTCTAAATTCATGTTAG
ATTTATCTTAACTATGTGGTATGTAAAT	TGTGATAGTGTTGAACAATTAAATCATACTTTCTTG
ATTTATCTTAACTATGTGGTATGTAAAT	TATTTTCCAGCTTCATATTGACCTAGTTTAACTCTTTCG
ATTTATCTTAACTATGTGGGAGTTTAAA

>NZ_CP042243|1|1|179464-180590|CRT
ATTTATCTTAACTATGTGGTATGTAAAT	ATAGGTTCGGTAAAAATTTTAAATGCAAATGAAAG
ATTTATCTTAACTATGTGGTATGTAAAT	TTAAAAAACTCAATGATTTCATCAAGGCTCTCTGACTC
ATTTATCTTAACTATGTGGTATGTAAAT	TTAAGCTTGGTAAAGGAGCTAGTATTCTCTTATCAGT
ATTTATCTTAACTATGTGGTATGTAAAT	TAAACTTTAAATTTTTCAGCAAAACTGTTCCTACCT
ATTTATCTTAACTATGTGGTATGTAAAT	AATAGCTCCCTCAATTCTTTAAGTGTCAATTTATCC
ATTTATCTTAACTATGTGGTATGTAAAT	TTTTATCAGCTACTTTTGTAACTGCTTCATTAGCAG
ATTTATCTTAACTATGTGGTATGTAAAT	GGTAATTATGAAGTTATTTTAAAACCTGTGAGTACT
ATTTATCTTAACTATGTGGTATGTAAAT	TTAAGGAAAATATACAAGATTTAAAAACTGCAAATG
ATTTATCTTAACTATGTGGTATGTAAAT	AAAAAATCACCAAGCAGACTATCATCTGTACCGCTG
ATTTATCTTAACTATGTGGTATGTAAAT	ATTTTAGGTTCAAATTCAATTGTAAATGGAAAATAT
ATTTATCTTAACTATGTGGTATGTAAAT	TGAAATATAAACGCTATACCTACAAGAAATCCGAAT
ATTTATCTTAACTATGTGGTATGTAAAT	ACTTTTCGAAATGAAAAATTGATTCAACTATTGCATGGG
ATTTATCTTAACTATGTGGTATGTAAAT	AGACAAACATTTCTTAGAGAAGCAGCATCCATCCCCG
ATTTATCTTAACTATGTGGTATGTAAAT	AATAGAAAATATCTAATCCTATACCACTAAAAATAAG
ATTTATCTTAACTATGTGGTATGTAAAT	GCATAGAGCTTAAGCGTATCTTCTAAATTCATGTTAG
ATTTATCTTAACTATGTGGTATGTAAAT	TGTGATAGTGTTGAACAATTAAATCATACTTTCTTG
ATTTATCTTAACTATGTGGTATGTAAAT	TATTTTCCAGCTTCATATTGACCTAGTTTAACTCTTTCG
ATTTATCTTAACTATGTGGGAGTTTAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042243.1\|WP_148808107.1\|186489_187089_-\|C26-family-cysteine-hydrolase-domain-containing-family	unknown	unknown	gnl\|CDD\|235552
NZ_CP042243.1\|WP_148808091.1\|170040_170991_+\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NZ_CP042243.1\|WP_148808101.1\|181993_182476_-\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	unknown	unknown	gnl\|CDD\|238269
NZ_CP042243.1\|WP_148808104.1\|183710_184271_-\|GTP-cyclohydrolase-I-FolE	unknown	unknown	gnl\|CDD\|236472
NZ_CP042243.1\|WP_148808095.1\|174396_175155_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|187789
NZ_CP042243.1\|WP_148808103.1\|182821_183688_-\|dihydropteroate-synthase	unknown	unknown	gnl\|CDD\|238380
NZ_CP042243.1\|WP_148808099.1\|180658_181204_+\|DUF2284-domain-containing-protein	unknown	unknown	gnl\|CDD\|378368
NZ_CP042243.1\|WP_148808100.1\|181224_182001_-\|3-deoxy-7-phosphoheptulonate-synthase	unknown	unknown	gnl\|CDD\|181535
NZ_CP042243.1\|WP_148808090.1\|167841_169836_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|223910
NZ_CP042243.1\|WP_148808102.1\|182468_182834_-\|dihydroneopterin-aldolase	unknown	unknown	gnl\|CDD\|376737
NZ_CP042243.1\|WP_148808106.1\|185129_186500_-\|aminodeoxychorismate-synthase-component-I	unknown	unknown	gnl\|CDD\|223225
NZ_CP042243.1\|WP_148808093.1\|171792_173493_+\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	cas8b2	cd09665_cas8b2_CAS-I-B	gnl\|CDD\|187884
NZ_CP042243.1\|WP_148808089.1\|166746_167550_+\|haloacid-dehalogenase	unknown	unknown	gnl\|CDD\|273651
NZ_CP042243.1\|WP_148808105.1\|184296_185112_-\|4-amino-4-deoxychorismate-lyase	unknown	unknown	gnl\|CDD\|223193
NZ_CP042243.1\|WP_148808098.1\|179012_179279_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP042243.1\|WP_148808094.1\|173485_174388_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|274215
NZ_CP042243.1\|WP_148808097.1\|177515_178037_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NZ_CP042243.1\|WP_148808108.1\|187122_187602_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224336
NZ_CP042243.1\|WP_148808096.1\|175204_177499_+\|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|273707
NZ_CP042243.1\|WP_148808092.1\|171054_171789_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848

Protein	Function_ID	Function_description	E-value
NZ_CP042243.1\|WP_148808107.1\|186489_187089_-\|C26-family-cysteine-hydrolase-domain-containing-family	gnl\|CDD\|235552	PRK05670, PRK05670, anthranilate synthase component II; Provisional.	4.16971e-127
NZ_CP042243.1\|WP_148808091.1\|170040_170991_+\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	2.79067e-43
NZ_CP042243.1\|WP_148808101.1\|181993_182476_-\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	gnl\|CDD\|238269	cd00483, HPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is HPPK which catalyzes pyrophosphoryl transfer from ATP to 6-hydroxymethyl-7,8-dihydropterin (HP). The functional enzyme is a monomer. Mammals lack many of the enzymes in the folate pathway including, HPPK.	1.07677e-70
NZ_CP042243.1\|WP_148808104.1\|183710_184271_-\|GTP-cyclohydrolase-I-FolE	gnl\|CDD\|236472	PRK09347, folE, GTP cyclohydrolase I; Provisional.	2.92002e-121
NZ_CP042243.1\|WP_148808095.1\|174396_175155_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|187789	cd09658, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	8.95036e-23
NZ_CP042243.1\|WP_148808103.1\|182821_183688_-\|dihydropteroate-synthase	gnl\|CDD\|238380	cd00739, DHPS, DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and protein biosynthesis. Prokaryotes (and some lower eukaryotes) must synthesize folate de novo, while higher eukaryotes are able to utilize dietary folate and therefore lack DHPS. Sulfonamide drugs, which are substrate analogs of pABA, target DHPS.	1.79616e-129
NZ_CP042243.1\|WP_148808099.1\|180658_181204_+\|DUF2284-domain-containing-protein	gnl\|CDD\|378368	pfam10050, DUF2284, Predicted metal-binding protein (DUF2284). Members of this family of metal-binding hypothetical bacterial proteins have no known function.	4.1856e-50
NZ_CP042243.1\|WP_148808100.1\|181224_182001_-\|3-deoxy-7-phosphoheptulonate-synthase	gnl\|CDD\|181535	PRK08673, PRK08673, 3-deoxy-7-phosphoheptulonate synthase; Reviewed.	8.98534e-162
NZ_CP042243.1\|WP_148808090.1\|167841_169836_+\|HAMP-domain-containing-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.7855e-60
NZ_CP042243.1\|WP_148808102.1\|182468_182834_-\|dihydroneopterin-aldolase	gnl\|CDD\|376737	pfam02152, FolB, Dihydroneopterin aldolase. This enzyme EC:4.1.2.25 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin in the biosynthetic pathway of tetrahydrofolate.	9.55578e-48
NZ_CP042243.1\|WP_148808106.1\|185129_186500_-\|aminodeoxychorismate-synthase-component-I	gnl\|CDD\|223225	COG0147, TrpE, Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism].	0
NZ_CP042243.1\|WP_148808093.1\|171792_173493_+\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	gnl\|CDD\|187884	cd09754, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as CXXC_CXXC family.	3.83568e-15
NZ_CP042243.1\|WP_148808089.1\|166746_167550_+\|haloacid-dehalogenase	gnl\|CDD\|273651	TIGR01484, Putative_mannosyl-3-phosphoglycerate_phosphatase, HAD-superfamily hydrolase, subfamily IIB. This subfamily falls within the Haloacid Dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. The Class II subfamilies are characterized by a domain that is located between the second and third conserved catalytic motifs of the superfamily domain. The IIB subfamily is distinguished from the IIA subfamily (TIGR01460) by homology and the predicted secondary structure of this domain by PSI-PRED. The IIB subfamily's Class II domain has the following predicted structure: Helix-Sheet-Sheet-(Helix or Sheet)-Helix-Sheet-(variable)-Helix-Sheet-Sheet. The IIB subfamily consists of Trehalose-6-phosphatase (TIGR00685), plant and cyanobacterial Sucrose-phosphatase and a closely related group of bacterial and archaeal sequences, eukaryotic phosphomannomutase (pfam03332), a large subfamily ("Cof-like hydrolases", TIGR00099) containing many closely related bacterial sequences, a hypothetical equivalog containing the E. coli YedP protein, as well as two small clusters containing OMNI\|TC0379 and OMNI\|SA2196 whose relationship to the other groups is unclear. [Unknown function, Enzymes of unknown specificity].	6.59016e-08
NZ_CP042243.1\|WP_148808105.1\|184296_185112_-\|4-amino-4-deoxychorismate-lyase	gnl\|CDD\|223193	COG0115, IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism].	6.36428e-69
NZ_CP042243.1\|WP_148808098.1\|179012_179279_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	6.19349e-28
NZ_CP042243.1\|WP_148808094.1\|173485_174388_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|274215	TIGR02585, conserved_protein, CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This clade is a member of the DevR family (TIGR01875) and includes the DevR protein of Myxococcus xanthus, a protein whose expression appears to be regulated through a number of means, including both location and autorepression; DevR mutants are incapable of fruiting body development.	9.52117e-59
NZ_CP042243.1\|WP_148808097.1\|177515_178037_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	1.4006e-59
NZ_CP042243.1\|WP_148808108.1\|187122_187602_-\|HD-domain-containing-protein	gnl\|CDD\|224336	COG1418, COG1418, Predicted HD superfamily hydrolase [General function prediction only].	1.18754e-13
NZ_CP042243.1\|WP_148808096.1\|175204_177499_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	1.95196e-64
NZ_CP042243.1\|WP_148808092.1\|171054_171789_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	1.95905e-21

>NZ_CP042243.1|WP_148808098.1|179012_179279_+|CRISPR-associated-endonuclease-Cas2
MFVIVTYDIVEPRVINKVRKILKKYLIWTQNSVFEGKITQGKLHQCLSEIGKVVDKSEDSIYVYRVGNHRNVTKDVIGQEKSFDELFL
>NZ_CP042243.1|WP_148808097.1|177515_178037_+|CRISPR-associated-protein-Cas4
MNFEFEKFKTQGVKVNYYYVCKRKLWLFSKGITMEDNSDRVLSGKLVHENSYPRQKNKEILIDNIFKIDIFDKEYVREVKISSKMSLSDKMQLMYYLYYLNQLGIQKKGVINYVKEKKQEIIELTEDMKKEIEKVLVDIKDIIENKTPLKAINLPYCKKCAYYEFCYVKEEEE
>NZ_CP042243.1|WP_148808096.1|175204_177499_+|CRISPR-associated-helicase-Cas3'
MKNPFLAKTENKETIIEHTEKLLERMEALKHIYSNIKNLDWNILELACLYHDLGKMNTKFQNKLIRKLRRVKEYTDEFPEDLQDEFTNMEEIPHGYLSPAFLPKDELKKKFSDDELRILYQSIYFHHSRKKLENHNELKRIVNEDLNKYIQDFKFDRIKSIEKLNESFIRYIKRRIPDQYDTPETIRQYIMTKGLLNKIDYAASGGIPIEVKNENLFEKTNTYLSSGGFKPNELQEYMIENQDKNNVIIASTGIGKTEASLFWIGNNKGFFTLPLKVSINAIYDRVVDKIKFGKENTGLLHSETSSEYLKRNNNELDIEYYDQTKQLSLPLTICTLDQLVDFIFKYEGYELKLATLSYSKLIIDEIQMYSPELVAFLIVALKYITELGGKFSIVTATLPPIFLDFMKEQNIVFNQPLPFYKKIDGKVQLRHKLKVFEEDINTDHIKKNYKNKKVLIIVNTVKKAQEIYKKLKLDLDNETEIKLFHSRFIKKDRSKKENMILDMGKLEIKRTGIWITTQVVEASLDIDFDVLYTELSDIAGLLQRMGRVYRNRDLKEGLVNIYVYVGKDKFPSGIGSGDQSIIDKDIFELSKQAILTYVGDEMNGKEIDEKVKMELVKQVYSKERLVESNYYKKIKETIKHVMDIKAYEFMKKEVNLRNIENQIVIPKNIYEENKEFIQNNLHTIQETSDYNKKLIAKNEIKEFTMSIPKYQYDEAKRNGYIQGDFIELDKYNKIPIISYPYSFEKGLTRPQKKLDEFDEDLQFI
>NZ_CP042243.1|WP_148808095.1|174396_175155_+|type-I-B-CRISPR-associated-protein-Cas5
MKAIRLRIYQNLVNYRKPTSFQLKETYPLPPYSTVSGMIHFVCGFEEYKEMDISVQGKYYSKVNDLYTRYEFAGTSYENGRHNIKIKSREINKKTGEEIDKYYGIIRGVATCELLVDVELLIHIKPKDEELVEVIYETLKNPKEYLSLGRREDIARIDEVKIVNVDEVEIEEDTTLEYDAYIPIKMFGIDDFNSNATVYNLNKKYEKVEVKKGTFIRQWEKVKVIHGVMNRNELAQEAVVYKDEDENLVFFA
>NZ_CP042243.1|WP_148808094.1|173485_174388_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MDKKGLTASFIFEAESGNYGEGIGNVTSLKKVSRGTGESYTYISRQALRFNIIEQMGENNTPLDVDGSVIQFAPDATIKDYAEIDLFGYMKTKKPTKTRAAVVRLSNAVSLESFNADLDFLTNKGLFDRYNAQGNEIKDGGNIAQSEIHKSYYAYTITIDLDKVGIDENYQDESGNPLEIKSEEKAKRVRSLLDTIKFLYRDIKGRRENLSPIFAIGGVYDIKNPFFENKLKVKNNKLVIDAIKDVYGLDKAIKESTHVGLIKGIFSNDVKIIEELNAKGMGEFFNSLKGEVEKYYSENE
>NZ_CP042243.1|WP_148808093.1|171792_173493_+|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1
MKTINKIRLELADWLYNAGIVGVANILDANDVAYKRGINYIEFEETALENFEEKYFKYFIDKYKKFTSWYNIVKYEDVILNFKEENVDEEYLENINKQIDYVKEKLKSASYKSAYVIIQNKEKDLLKEEKQLNKIKKNKKQKVEDVLPNIKEQLNRMQQIIEYLKTDEVAKIILAKNIIYDIIAKFWSDVSFLNKNNNKKNMYEEYRIYFVDGTLQYIEKIIEKAKYKCFVCDRKISKLSKPVSYDLTWINKMGVDMSRKTSHFWDLSGDTFICPICNFVYSCIPAGFTVIKGQGLFINQNSSINNLIAVNKHALERNTTFEELEDASYFSIVENINQNKVEQLDKEIENIQIIKLDSTNVVRPYTFNILSKDKLKVMNGNKKMLQSMIKVKVKVGTKEYLNLYKEVVTRLYEGKNQFDLINQLFHLRLDKKFNKLHFIDMIIKINNNFIGGREKKKMVHHKVINDCKGFGLDLRISYVNKKAENKLNGISYRLLNALKTKNTSKFMDTLLNAYMYLNKQVPTIFIEGLKDTDKFQTLGYAFLLGLQGEEMKENKKDDIKEDMING
>NZ_CP042243.1|WP_148808092.1|171054_171789_+|CRISPR-associated-endoribonuclease-Cas6
MRLKCEYKTKEIPVGYNMLLVSLIKEALKKSDENYFNKLYKYDENIANKRSKNFTFAAYIKNYERAEEIFKVNDRVILNISSPDLEFMINLYNGLLKLSKFQYKTFELYKLKIDLIKEKKLATNEVIFKTLSPICIKNKNNYFMKIEDDKYIDELNYIANLVLKNYRGEGLRENLMFMPLDMKKVVVKEEIRGFKSKTNRKYLYVNSYSGTFKMKGNVKDLEDLYALGVGFKRNQGFGMIEVIG
>NZ_CP042243.1|WP_148808091.1|170040_170991_+|WYL-domain-containing-protein
MSKVGNELKMLMILQSRGKMKAKDLAREIEVSEREIRRYKDDLIQAGIYIESDAGKYGGYSIGNDSYLLCLNFTDQEYMALLMINEELKKSNHLVLKDYNTAIDKINIVHKKKMHNLSNSYNYMLKGAIANINFQKERKKLIDIHAAILTKNKVNIKYTSLTSGQTERVVWPYATFQYKGDMYFTGYCERRKATIYFKLCRVNKYSVLEEKFEMDKPFDLEEYMKNCFGIFKDQAIQVKLKIHYPMSQIVKEKIWVENQKIIENEEDKSIIFEAMMEGLEEIKSWILSMGGSVEVIEPKMLIEEIKKEIEKMKSIY
>NZ_CP042243.1|WP_148808090.1|167841_169836_+|HAMP-domain-containing-protein
MEKKTKNRKGIRFRLTVIFTLLIALSLFTLGATSFFKSVNVTESKLKDSSLQLVKELNVSITNYLDGIEKFVCVLANSQVKKIRSNPEAIDEIMNEFETFKNSHKDIKYIYIGTKDKKIYPKPSKSYDPTQRPWYKKAIQAKKLIWTKPYKDISTGEYVISAAIPVYDKNNELIGVLAADIALKTLEEMIDGTKIGKKGYPFVLDENGKVIFHKNKELIGKVLPVEKIIKSIETKKEDIVNYKWEEDGEVYEKFVVYSTLEKLNWKVMGNMYVNEIEEETSGILKNTLTVGAVSLLIVVLITYLFATSLTNPIKELVYDMERVKEGDLSVRCNVKNKDEIGQLSENFNIMVEELGKLVGKMKDVSIEVTSSAQNLAATTEVSSASAEEVAAAVEAIAKGAADQAVDAEKGANLTLKLSSKFDQLEGDFDHIRKSAEDVMATSEASVDVVNELKEKTELNNEGTEKIEEAIIDLDHRIQDIGNILETIDAIADQTNLLALNASIEAARAGEAGRGFTVVAEQIRKLSEESRISSDEIKQIITNVQKESEHTVEIMKELKERSLGQSESVEKVHGSFEQIETAVHSITEKIESISKFVNQINNEKELIVKAIENISAVSEETASSSEEVNASMQQQAMIVEEIATAADKLDDLAVKLNSEISRFKV
>NZ_CP042243.1|WP_148808089.1|166746_167550_+|haloacid-dehalogenase
MIFASDLDRTLIYSKKFVSNDEGIKLIETKGKEEISFMTKKAIKRLKKLSEEILFIPVTTRTIEQYRRISLFQEEIRPKYAIVSNGGNILINGEIDYEWNNIIQKKIKEECISFKEVESKFEEIESNQWVINRKVADNLFSYCIIHPEYVPEVLYSFIDWMEDNNWKVSLQGRKLYFVPCCVCKWEATQYIKMRENIDFVASAGDSLLDLPMLKMADYAVVPPHGEIYKKYERTYETIQNITFTEKEGIFAAEEILEKIYGLIKQPV
>NZ_CP042243.1|WP_148808099.1|180658_181204_+|DUF2284-domain-containing-protein
MDKIKVLKNYINTKNIDFMQEISPKELLVSQKVRDACIKNKCGQYNNNFMCPPYVGEIEDFLKKLEGYTKGFLIFVKDKIDDPSDLNQFYKSATILHEIMLDIEKKGKELGFHKAFALIGGNCRLCDVCNAKLGKDNCINPKMARPSLEAVGIDVIHTCSQKGITIEFRKDEVIWVGLLLV
>NZ_CP042243.1|WP_148808100.1|181224_182001_-|3-deoxy-7-phosphoheptulonate-synthase
MNKQILTGKEIVVSVGNLKIGGNNPPIFIAGPCSVESREQILETALALKKIGVHILRGGVFKPRTSPYDFQGLEIEGLKYLKEAGNQAEIPIITELMDEKNLDIVLEYADIIQIGSRNMYNYSLLKTLGNIDKPILLKRGMSATVREWMMAAEYIAAYGNTNIILCERGIRTFETYTRNTLDLSVVPIMKNETGLPVIVDPSHGTGIRELIKPMSKAALACGADGLMIEVHPNPEKALSDGHQSLTIEQYKELFEEIN
>NZ_CP042243.1|WP_148808101.1|181993_182476_-|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase
MSRAYLGIGGNMGNKKENIQNTIKLLKNHPQIHVSAISSYYETAPVGYTDQDWFLNIVVEINTSLDPYALLAYCNDIEQKLKRERLIRWGPRTIDVDILLYEGFTSDDEKLTVPHPRMCERAFVMVPLYEIAKDLVINNKKIEDIIKNLKGEEVRKIKNE
>NZ_CP042243.1|WP_148808102.1|182468_182834_-|dihydroneopterin-aldolase
MDKIIMKNLSFYGYHGAMPEENIIGQKFFVDIDLYLDLKKAGNTDCVAHTVHYGEAYEVVKNIVENKKFNLIEALAENIAKEILEQFSLVKEIHITIRKPEAPVKGIFDYFGVEIRRKQNE
>NZ_CP042243.1|WP_148808103.1|182821_183688_-|dihydropteroate-synthase
MKNTKYDFSRKVTIKCGEYTLNLGSKTYIMGILNVTPDSFSDGGKFIHLDKAILHAKEMAAQGADIIDIGGESTRPGHQEISVEEEIKRVLPVVERLVKELNVPISVDTSKAAVAEAVLNAGAHMINDVWGLQKDMNMAKVVAKYNVPVCIMHNQNTTEYKKDIIQSIKEFLKKSIEIALSSGIKKENIILDPGIGFGKTPEQNIHVMSRLDEFNDMGFPILLGTSRKSMIGKILDLPPNERIEGTIATSVIGIMQGMDILRVHDITENLRAIMVADAIVRGTKPWIK
>NZ_CP042243.1|WP_148808104.1|183710_184271_-|GTP-cyclohydrolase-I-FolE
MDKARIEKAIREILEAIGEDPNREGLKDTPKRIAKMYEEIFSGLNEDPKKHLEIFFQEEKHEELVLVKDIPFYSMCEHHFVPFFGKAHVGYLPKNGRLTGLSKLARVVETVAKRPQLQERLTSSIAEALVEKLDPYGVIVVVEAEHMCMTMRGVKKPGSKTITSAVRGLFERDAKARSEAMALIKF
>NZ_CP042243.1|WP_148808105.1|184296_185112_-|4-amino-4-deoxychorismate-lyase
MCISFNGTLIKSKETCISPESEAFLYGYGIFETLKIHCGKIFFIDEHLERLKKGCKELNIKLDYDLKKIQKYCYNLINSNSMVFGALKILYAKNKDQYNLLLFTRENIYTEEKYKKGFHICFADTKKNPYSKLTYIKSNNYLENILEKQKAKENGYDEAIFLNVLNKISEGTYTNIFFIKNNILYTPATECGILPGIMRNKIIDLIYKLNLNLKIGTFNKADLFNADEIFLTNSLMDIMPVSQLENKVFDLSKNYVTKLLQKSFYNLYYHQ
>NZ_CP042243.1|WP_148808106.1|185129_186500_-|aminodeoxychorismate-synthase-component-I
MLIKKINTSLNSFELYTLFKNEPYSFFLDSGMDPNKLGKYSFIGSNPFLIFKSKNNKIDICENGKTTVLNGDPLEKLREILSSYKMDYKTDLPFIGGAVGYLGYDLCHHIEKLPRHAVDDVNIPDCYIGLYDGIIIIDHQKEEVFASALGIKSPEEETIQKIINTIKAGEEKGVNIKIPKNNKPINLKSNFKKEDYIKAINKIKSYIKAGDIYQANMTQRFECDLQITPFELYAKLREINPAPFASYIDFGEGQIVSSSPERFIQIKNRIIETRPIKGTRPRGKTPTEDIKNREELLSSEKDKAELLMIVDLERNDLGKVSKTGTVEVTELFHLEEYATVYHLVSTIIGKMKDDCDVIDCIKATFPGGSITGAPKIRSMEIIDELEPTQRNIYTGSIGYIGFNGDTDLNIVIRTILCKNQKAYFQVGGGIVWDSDAELEYEETLHKAKALIKALES
>NZ_CP042243.1|WP_148808107.1|186489_187089_-|C26-family-cysteine-hydrolase-domain-containing-family
MILMIDNYDSFTYNLVQYLECLSEDVLVYRNDCITLEKIEKLNPYMIVLSPGPCTPNEAGICKDVVTTFKGKIPILGICLGHQTIGQVFGGNIIKAKEPVHGKVHPIKHENKGVFKDLPNPLKVTRYHSLVVEKESLPDCFEITAKTFQGEIMGIKHKEYLIEGVQFHPEAILTEKGMEILENFLIEAKKWTSRCKNVD
>NZ_CP042243.1|WP_148808108.1|187122_187602_-|HD-domain-containing-protein
MERVNKILHNPKYIDYLNRNAQAEKNRIFCHHDLRHAIDVARVSYILALEENLSIKKEVIYAAALLHDIGRWKEYLQGIDHASASADLASEILKESGYIKEEKDLIYSAIRNHRKYNKQNPPLDKILYKSDKISRPCSECLVINQCKRFLNGGNPKIDY

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Crispr_ID: NZ_CP042243_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042243_2

802001-802761

TypeIII

Consensus_repeat	Method
GGTTTCATAGTTCCTATAAGGAAGTGGAAT---------ATTT	PILER-CR
GGTTTCATAGTTCCTATAAGGAAGTGGAATT	CRISPRCasFinder
GTTTCATAGTTCCTATAAGGAAGTGGAAT	CRT
CGTTTCATAGTTCCTATAAGGAAGTGGAATTTAGAATTCATTTATCTA	PILER-CR

11 spacers

cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10

The CRISPR arrays of NZ_CP042243_2

>merge|NZ_CP042243|2|802001-802761|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GGTTTCATAGTTCCTATAAGGAAGTGGAATATGGCAAAAAATAAGCAGACGCTGAAGCAATGCTCTGGTTTCATAGTTCCTATAAGGAAGTGGAATATTTTTTACTCTCAATAATTCAACAGAATTAATATTCGGTTTCATAGTTCCTATAAGGAAGTGGAATTTTTCTAGCACGATATGAGCATTGCCATTACTATCAAAGGTTTCATAGTTCCTATAAGGAAGTGGAATTAGCTAATTTTTCACCTTCAAATTCTTCTACAATTTGGGTTTCATAGTTCCTATAAGGAAGTGGAATTTACGAGAGATGAGTATTTAGAGTTATTGAAAAGAGAGTTTCATAGTTCCTATAAGGAAGTGGAATTTTTATTTGATTTATCTATTGCCCCTATTGTTATTACGTTTCATAGTTCCTATAAGGAAGTGGAATATTAATAGTTGAAGGTTCACATTTCATTAATTTTGCGTTTCATAGTTCCTATAAGGAAGTGGAAATTAGGATTCGTTTTTCTAAGCTGATCAAATCTATGAGGTTTCATAGTTCCTATAAGGAAGTGGAAATTATATTCTTAAAATTTTATATAACAACAACTATATGTTTCATAGTTCCTATAAGGAAGTGGAATAAAGGAATGACAAGGTCAATTTCTTCTGTGTACGGCTCGTTTCATAGTTCCTATAAGGAAGTGGAATATTACATTGGCTATATCTTTTGCTACACTCGGTTTTTCGTTTCATAGTTCCTATAAGGAAGAGAAGTT

>NZ_CP042243|2|2|802001-802167|PILER-CR
GGTTTCATAGTTCCTATAAGGAAGTGGAATATGG	CAAAAAATAAGCAGACGCTGAAGCAATGCTCT
GGTTTCATAGTTCCTATAAGGAAGTGGAATATTT	TTTACTCTCAATAATTCAACAGAATTAATATTC
GGTTTCATAGTTCCTATAAGGAAGTGGAATTTTTCTAGCACGATATGAGCATTGCCATTACTATCAAAGGTTTCATAGTTCCTATAAGGAAGTGGAATTAGCTAATTTTTCACCTTCAAATTCTTCTACAATTTGGGTTTCATAGTTCCTATAAGGAAGTGGAATTTACGAGAGATGAGTATTTAGAGTTATTGAAAAGAGAGTTTCATAGTTCCTATAAGGAAGTGGAATTTTTATTTGATTTATCTAT	TGCCCCTATTGTTATTAC
GTTTCATAGTTCCTATAAGGAAGTGGAATATTAATAGTTGAAGGTTCA	CATTTCATTAATTTTGCGTTTCATAGTTCCTATAA


>NZ_CP042243|2|2|802001-802761|CRISPRCasFinder
GGTTTCATAGTTCCTATAAGGAAGTGGAATA	TGGCAAAAAATAAGCAGACGCTGAAGCAATGCTCT
GGTTTCATAGTTCCTATAAGGAAGTGGAATA	TTTTTTACTCTCAATAATTCAACAGAATTAATATTC
GGTTTCATAGTTCCTATAAGGAAGTGGAATT	TTTCTAGCACGATATGAGCATTGCCATTACTATCAAA
GGTTTCATAGTTCCTATAAGGAAGTGGAATT	AGCTAATTTTTCACCTTCAAATTCTTCTACAATTTG
GGTTTCATAGTTCCTATAAGGAAGTGGAATT	TACGAGAGATGAGTATTTAGAGTTATTGAAAAGAG
AGTTTCATAGTTCCTATAAGGAAGTGGAATT	TTTATTTGATTTATCTATTGCCCCTATTGTTATTA
CGTTTCATAGTTCCTATAAGGAAGTGGAATA	TTAATAGTTGAAGGTTCACATTTCATTAATTTTG
CGTTTCATAGTTCCTATAAGGAAGTGGAAAT	TAGGATTCGTTTTTCTAAGCTGATCAAATCTATGA
GGTTTCATAGTTCCTATAAGGAAGTGGAAAT	TATATTCTTAAAATTTTATATAACAACAACTATA
TGTTTCATAGTTCCTATAAGGAAGTGGAATA	AAGGAATGACAAGGTCAATTTCTTCTGTGTACGGCT
CGTTTCATAGTTCCTATAAGGAAGTGGAATA	TTACATTGGCTATATCTTTTGCTACACTCGGTTTTT
CGTTTCATAGTTCCTATAAGGAAGAGAAGTT

>NZ_CP042243|2|2|802002-802760|CRT
GTTTCATAGTTCCTATAAGGAAGTGGAAT	ATGGCAAAAAATAAGCAGACGCTGAAGCAATGCTCTG
GTTTCATAGTTCCTATAAGGAAGTGGAAT	ATTTTTTACTCTCAATAATTCAACAGAATTAATATTCG
GTTTCATAGTTCCTATAAGGAAGTGGAAT	TTTTCTAGCACGATATGAGCATTGCCATTACTATCAAAG
GTTTCATAGTTCCTATAAGGAAGTGGAAT	TAGCTAATTTTTCACCTTCAAATTCTTCTACAATTTGG
GTTTCATAGTTCCTATAAGGAAGTGGAAT	TTACGAGAGATGAGTATTTAGAGTTATTGAAAAGAGA
GTTTCATAGTTCCTATAAGGAAGTGGAAT	TTTTATTTGATTTATCTATTGCCCCTATTGTTATTAC
GTTTCATAGTTCCTATAAGGAAGTGGAAT	ATTAATAGTTGAAGGTTCACATTTCATTAATTTTGC
GTTTCATAGTTCCTATAAGGAAGTGGAAA	TTAGGATTCGTTTTTCTAAGCTGATCAAATCTATGAG
GTTTCATAGTTCCTATAAGGAAGTGGAAA	TTATATTCTTAAAATTTTATATAACAACAACTATAT
GTTTCATAGTTCCTATAAGGAAGTGGAAT	AAAGGAATGACAAGGTCAATTTCTTCTGTGTACGGCTC
GTTTCATAGTTCCTATAAGGAAGTGGAAT	ATTACATTGGCTATATCTTTTGCTACACTCGGTTTTTC
GTTTCATAGTTCCTATAAGGAAGAGAAGT

>NZ_CP042243|2|3|802336-802513|PILER-CR
	CAAAAAATAAGCAGACGCTGAAGCAATGCTCT
GGTTTCATAGTTCCTATAAGGAAGTGGAATATTT	TTTACTCTCAATAATTCAACAGAATTAATATTC
GGTTTCATAGTTCCTATAAGGAAGTGGAATTTTTCTAGCACGATATGAGCATTGCCATTACTATCAAAGGTTTCATAGTTCCTATAAGGAAGTGGAATTAGCTAATTTTTCACCTTCAAATTCTTCTACAATTTGGGTTTCATAGTTCCTATAAGGAAGTGGAATTTACGAGAGATGAGTATTTAGAGTTATTGAAAAGAGAGTTTCATAGTTCCTATAAGGAAGTGGAATTTTTATTTGATTTATCTAT	TGCCCCTATTGTTATTAC
GTTTCATAGTTCCTATAAGGAAGTGGAATATTAATAGTTGAAGGTTCA	CATTTCATTAATTTTGCGTTTCATAGTTCCTATAA
GGAAGTGGAAATTAGGATTCGTTTTTCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042243.1\|WP_148808691.1\|799090_799942_+\|hypothetical-protein	csm4gr5	mkCas0089_csm4gr5_CAS-III-A:CAS-III-D	unknown
NZ_CP042243.1\|WP_148808701.1\|818533_819058_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042243.1\|WP_148808687.1\|793289_793646_-\|oxidoreductase	unknown	unknown	gnl\|CDD\|213664
NZ_CP042243.1\|WP_148808689.1\|796347_796815_+\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl\|CDD\|367635
NZ_CP042243.1\|WP_148808697.1\|810432_811593_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	unknown	unknown	gnl\|CDD\|131032
NZ_CP042243.1\|WP_148808685.1\|790321_791671_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|181958
NZ_CP042243.1\|WP_148808693.1\|801057_801816_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|224499
NZ_CP042243.1\|WP_148808696.1\|806701_810358_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042243.1\|WP_168198226.1\|793935_796347_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
NZ_CP042243.1\|WP_168198227.1\|811676_813824_+\|DUF262-domain-containing-protein	unknown	unknown	gnl\|CDD\|226003
NZ_CP042243.1\|WP_148808702.1\|819066_820146_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|223642
NZ_CP042243.1\|WP_148808690.1\|798424_799075_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NZ_CP042243.1\|WP_148808700.1\|816539_818522_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|274475
NZ_CP042243.1\|WP_148808695.1\|804046_805789_+\|phosphoadenosine-phosphosulfate-reductase-family-protein	unknown	unknown	gnl\|CDD\|237510
NZ_CP042243.1\|WP_148808692.1\|799938_801018_+\|hypothetical-protein	csm5gr7	mkCas0182_csm5gr7_CAS-III-A	gnl\|CDD\|273863
NZ_CP042243.1\|WP_148808699.1\|814183_816373_+\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|274978
NZ_CP042243.1\|WP_148808686.1\|791905_793246_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042243.1\|WP_168198228.1\|816384_816549_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042243.1\|WP_148808684.1\|789791_790154_+\|DUF134-domain-containing-protein	unknown	unknown	gnl\|CDD\|224261
NZ_CP042243.1\|WP_148808694.1\|803207_803747_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235234

Protein	Function_ID	Function_description	E-value
NZ_CP042243.1\|WP_148808687.1\|793289_793646_-\|oxidoreductase	gnl\|CDD\|213664	TIGR01909, Uncharacterized_protein_AF_0456, C_GCAxxG_C_C family probable redox protein. This model represents a putative redox-active protein of about 140 residues, with four perfectly conserved Cys residues. It includes a CGAXXG motif. Most members are found within one or two loci of transporter or oxidoreductase genes. A member from Geobacter sulfurreducens, located in a molybdenum transporter operon, has a TAT (twin-arginine translocation) signal sequence for Sec-independent transport across the plasma membrane, a hallmark of bound prosthetic groups such as FeS clusters.	1.60866e-21
NZ_CP042243.1\|WP_148808689.1\|796347_796815_+\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	0.000271701
NZ_CP042243.1\|WP_148808697.1\|810432_811593_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	gnl\|CDD\|131032	TIGR01977, am_tr_V_EF2568, cysteine desulfurase family protein. This model describes a subfamily of probable pyridoxal phosphate-dependent enzymes in the aminotransferase class V family. Related families contain members active as cysteine desulfurases, selenocysteine lyases, or both. The members of this family form a distinct clade and all are shorter at the N-terminus. The function of this subfamily is unknown. [Unknown function, Enzymes of unknown specificity].	4.83904e-147
NZ_CP042243.1\|WP_148808700.1\|816539_818522_+\|AAA-family-ATPase	gnl\|CDD\|274475	TIGR03185, DNA_S_dndD, DNA sulfur modification protein DndD. This model describes the DndB protein encoded by an operon associated with a sulfur-containing modification to DNA. The operon is sporadically distributed in bacteria, much like some restriction enzyme operons. DndD is described as a putative ATPase. The small number of examples known so far include species from among the Firmicutes, Actinomycetes, Proteobacteria, and Cyanobacteria. [DNA metabolism, Restriction/modification].	2.39371e-18
NZ_CP042243.1\|WP_148808693.1\|801057_801816_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|224499	COG1583, COG1583, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	4.09082e-23
NZ_CP042243.1\|WP_168198226.1\|793935_796347_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	1.97442e-57
NZ_CP042243.1\|WP_168198227.1\|811676_813824_+\|DUF262-domain-containing-protein	gnl\|CDD\|226003	COG3472, COG3472, Uncharacterized conserved protein [Function unknown].	2.17305e-15
NZ_CP042243.1\|WP_148808702.1\|819066_820146_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|223642	COG0568, RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription].	3.24724e-41
NZ_CP042243.1\|WP_148808690.1\|798424_799075_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	6.10753e-59
NZ_CP042243.1\|WP_148808695.1\|804046_805789_+\|phosphoadenosine-phosphosulfate-reductase-family-protein	gnl\|CDD\|237510	PRK13795, PRK13795, hypothetical protein; Provisional.	4.12163e-70
NZ_CP042243.1\|WP_148808692.1\|799938_801018_+\|hypothetical-protein	gnl\|CDD\|273863	TIGR01899, cas_TM1807_csm5, CRISPR type III-A/MTUBE-associated RAMP protein Csm5. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm5, for CRISPR/cas Subtype Mtube, protein 5.	5.44054e-06
NZ_CP042243.1\|WP_148808699.1\|814183_816373_+\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|274978	TIGR04095, type_III_restriction_protein_res_subunit, DNA phosphorothioation system restriction enzyme. The DNA phosphorothioate modification system dnd (DNA instability during electrophoresis) recently has been shown to provide a modification essential to a restriction system. This protein family was detected by Partial Phylogenetic Profiling as linked to dnd, and its members usually are clustered with the dndABCDE genes.	6.73548e-166
NZ_CP042243.1\|WP_148808685.1\|790321_791671_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|181958	PRK09564, PRK09564, coenzyme A disulfide reductase; Reviewed.	4.15444e-81
NZ_CP042243.1\|WP_148808684.1\|789791_790154_+\|DUF134-domain-containing-protein	gnl\|CDD\|224261	COG1342, COG1342, Predicted DNA-binding proteins [General function prediction only].	1.10222e-32
NZ_CP042243.1\|WP_148808694.1\|803207_803747_+\|hypothetical-protein	gnl\|CDD\|235234	PRK04164, PRK04164, hypothetical protein; Provisional.	2.13889e-16

>NZ_CP042243.1|WP_148808693.1|801057_801816_+|CRISPR-associated-endoribonuclease-Cas6
MKLKIILQAKEFFALPINYNHMLQNKILELLNKKNSNFLHNEGYKVKWKSFKLFNFSSLEVEKKKICKNKIFVYPGKVILGISSADENFIFDFIDGIITNKGIDFKEGKLDLVSIFSSKELNGNKLVVFAKTPIVVTKPYSEKAIDFFTPRDAEYLASIEKNLKDKYEAFYNKKYDKELEIEIMDESKVYKKIRKYKKWVYEGYIMGVILNGNNDILNLAYKTGLGSKNAQGFGFVETFSSLNSLKNYIKVV
>NZ_CP042243.1|WP_148808692.1|799938_801018_+|hypothetical-protein
MIWGKKYNVYLKPISHVCVGSGEEYQSYEYIRDTKEKKIYLLDDNKIMELIREGIIKVEDIDVGLKELLNIIKEKDILHRFKSAYIDNCNKLVIKKFYKTLSIVDDEKIEYIATIPASTIKGLIRSGYDSYIIKVKNKKIRYKYIRKVEKDQNNKSKMKYKLKGICNEKKLLDNNNAFENNLLEKNLDQLFSKIKVNDLFISEDKFLNIKKAHRYNRKKCKTVISSYYEAVDSEATFYGSIQLQDDESILMNAIKGLKELATSNIKVERKLLKEVVEKCFYEKLEEENRKEYQAVVKIGFGGLIGKTFVSYDEKSNERYDDEFLPYTILTTESSYKYGKFKKQKPMGWAVLTIKENKED
>NZ_CP042243.1|WP_148808691.1|799090_799942_+|hypothetical-protein
MIYKARFKMKNMAVKLISSVIFGNMARVLFELFSENDAKALIQDMVGKDCMLISDAVTEDIFKKSGKIASCVEDLINGKEYRGKELLKVREEYRKYKNLLKKEEDNTTEIPRIRVGIDRRTLKAEDKKLHYQNEYWSNKDVIYNIYIYTENEKVIKLLEIVFNILERTGIGTDTTIGCGAIAFIKEGKNIFKKDDTIKLAFKKEGGINIASTIVDQNYLVDIDIQNYVINRYDSKSPNIKKPPYYYIERGCIINKEEYVPPQLKEYKGIWVYNCVFPVERSNK
>NZ_CP042243.1|WP_148808690.1|798424_799075_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MSKLVKIKTLKTVMKVISGIRIVGNSTEINIGGIDNPIIKEPLEGYPYIPGSSLKGVMRSLAEKSKGLDSLCDCDNCKICTLFGSAKADSKSLRRLIVRDSYLTENSKKILDKFLPYGAEIKKENTINRTTGKATPRTLDRIPKGVSFNIYFTIKLYENDKEEDYISFLKSLLKMIEFSGIGGSISRGYGQVSFSELKIEDTYDIEEELNKYLNNN
>NZ_CP042243.1|WP_148808689.1|796347_796815_+|type-III-A-CRISPR-associated-protein-Csm2
MGSVFSEINTMIKKGFMENGKLKIEVIDKIDYLSDKINKLKISNSSIRKIYDNLKDIELKVNKQVLRNLSENEQIDFDEEEKKAFKEIKVDIKLMKSKINYILERKIENEKKNKYEYINLKNFLSNCLNKIETKEDFKGFLDLLECIIGYMKDQL
>NZ_CP042243.1|WP_168198226.1|793935_796347_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MNINEKLCVAIGGLFHDIGKVLRRSRLKSKGKSHSIQSEKYVKDYFSNIDFLKDEELELIEYIARYHHVSDENISKALKENSMMEEVLKYIKYVKKADGESAGERKIEGKNKRSIEDNPFTNMLSLMWQAFNDRKYNSNFNYFRPNIFSRLNMPKKYIEKEEISSYVNIMKNELGRDLDNLRQYNERFKEHEDEFVACLQYLMKEYTSYITSCGKEIVRDISMYNHSVTTAALALCRCIDEKDKQRINEYILLHGRIYDIQKYIYGDINKRIEKPLRRVLTRSNIISILNTIIPYEIIQELKLYTTNILFCGGGTFSLLLPKKYEDEAEKIIERIKKKVAEIFENKIYIEYVLKTINVRDKKKEYSYKTHKKYMKEFYEYKKDFQKANNELNQKKYNRSIYLIDFNKNCKEEYYKCSNCGINTKRRDKCSICQIEENWMDKDIYDVKIAYEKMRVENIEAYEKLEATKKGQTVILFDEKNIEKYKDKYPIGGIYPVGKYSIPKSNELCKKCSIKDICDEKSDGKILSLTCIEKLSKNERLVATAKIDLDDMAFLMYYIYPVSKKDKKSKNVEKYPFAISRLANLADLINVFFTQHLVSVVKNKYTEDIFILYSGGDDILLTGNWERVYDFVLEINKTFNRYIGQKSEKRNITLTSSIVLHKATRPFNMVLKEVNRNMSLAKETKNLVIINEVIQEQESRFRGICINYKNLKKAKKIISKYTEWIEEEKISRGLLYDLVTIMNMRKKGGIEALKGASILNYILEKNEVDIDISNEIKALIKEKEIDLSIFILKTAIRKSKKEEL
>NZ_CP042243.1|WP_148808687.1|793289_793646_-|oxidoreductase
MAINYYREGYNCAESIIQSVNEKKKINIPVCIGSPFGSGMSTGSVCGAATAAVVAIGYLKGRNHSTEQNKAARYSKDLIKKIREKFGSEICIDLKRKGVSCKEIIQFVDDYLKTLTQE
>NZ_CP042243.1|WP_148808686.1|791905_793246_+|hypothetical-protein
MKMNKKKLLNISLNIVMLVVLQVMSYYGKIYYEGYKDLKNNMYYNFEDFGEALETFNDELSKILVLGYDDFDKKKEFIDESIVRAFHRSNWDASDMGKGKAIYDYDFMYLNINKVIHNLLDDGNITLSEEKYIKSLYEYNEELIKEYNNILGDVRYNWNFGKIHALEKRIASIYNDYSQKADKLLETPKYKFLKEYEGEFKEVGFEHAKAYCEEVFSKLVKNQRLKYDNKDEANNDEYVFKNYKELDHNKELFTVKNDISDIDYKVTYNKKTKKVTVMAVSYIVPKKKYKEDELDNIVKNTIAKFNQNVVNYYKSKKYDSEGKLSYITYLYIEKNNDIYDEMKKIKINIKIHGLISKLEIIDHNDKPIILPNVSKKDILSKIDKEAEIIDAFIIRNMKGTAYVVHLKYGDTLYEAVFDGEDGKIIYYGRNIKKDYLNNLNKKNKND
>NZ_CP042243.1|WP_148808685.1|790321_791671_+|FAD-dependent-oxidoreductase
MKKTDLLIIGGSAGGLLTATAARKLYGDIKITLIRKNKKVMVPCGIPYIFGTLNDTSKNQIPDALLSNAGVELLIDEVVKIDRDKKMVITADNTEIEYDKLVIATGSLPIVPKFIKGYDLENVFPIVKDEEYLKDILEKVKNMSDIVVIGGGFIGVEFAEQMKMAGKNVTLVEVADKCLWQAFDEEFSSDAEEQLKNNGVIVKTKTKVEEIIGDTKVKEVKLSNGETIKADAVILGMGVSPNSVLAKDAGIKVNEKAAIIVDEYMRTNDSDIFAVGDCTEKKCFFTGKNTPILLASTAAMEAKIAACNLFQLKYVRKIKGTISAFSTKVFDKAFAAAGLTERKAKEEGFDIVIGRASTMDKHPGSLPNTGKIDIKLIFAKDTGIILGAQISGGDSIGEMVNILSMAVQNSMTANELNTYQVATHPLLTASPIAYPINAAALDALTKLNK
>NZ_CP042243.1|WP_148808684.1|789791_790154_+|DUF134-domain-containing-protein
MSRPRKWRRICNMPKIDVFGPCIRDININETIQMTLEEFETIRLIDYEGLSQEECGQIMGVARSTIQRIYNDARKKIADSIINGKYLKIKGGNYKLCDEIEGMNICKGCVRKRHRGGRNI
>NZ_CP042243.1|WP_148808694.1|803207_803747_+|hypothetical-protein
MTQSIIFALIGVFLITAFTNVLATLKTILISKKIMNPVYFLVFLDAMIFATIVAKMTSSKGIHFTIAYALGKTMGVFIGGKIEERLALGIFEVDVFFNNKNKMIQIAEKLREAGYTVNNFLARGNNGYKRYKVEVVIKRKEFNVLEDIMDACGVHNPTLKIKNVNKINGKITTTRIKAV
>NZ_CP042243.1|WP_148808695.1|804046_805789_+|phosphoadenosine-phosphosulfate-reductase-family-protein
MWCKICNKIVNDKKCPDCGNRTQEDIPIKVYWCDTCSIPIIKEVNDKTIHQCPLCEDEIKYIGKDLRPVFPEERLLIEVLKDKPLKYKDASVWSSANRYYINGSRYRISTKEMKEANPNKIRNQILKYQEKNKNTYNGFYEIIKKFIKANKERLNKLKNEAHSFIQKSREGYKDIQVIVSFSGGKDSTVVSDLVMKALSNPKIVHIFGNTTLEFPLTIEYKDRFRKNNPKTILREAKNTDQEFYTVCDEIGPPSRVMRWCCTMFKTGPINRVISSIFREKSVLTFYGIRKFESTSRSKYDRIYDSPKILKQKVAAPIFNWRDIDLWLYMLAENLDFNDAYRLGYDRVGCWCCPNNSERSHFLNEIYMPDQTKKWRNYLIDFAKKIGKPDPEVYVDSGNWKARQGGYGVDAAKDVKIVYTNCTTEVNAKIYSLNRPLSDEFYNLFIPFGKVSKELGRKLIGEVLVLHPKTNIPIISIQPFKTDEYETSVKIQTLNVKDYDKVQRMISYQVRKYNACKKCLGCETVCIYRAIKVGNDGYKIDENKCKRCMKCVTAKHLEYGCLMGKYLFTASSSEEDNWSEI
>NZ_CP042243.1|WP_148808696.1|806701_810358_+|hypothetical-protein
MNKHVQPISEFIHTAPGFQYSINLKYDLQSVEKIQNYIATSSAMDIIEDILLSVSLSSNDRARLLIGPYGKGKSHLVLIIIALLYYKDKELFINILDKIQKYNEDLYKLALKIIEDKEKILPVIISGNSLNLNQSFLAGLKNALLSEELVDIMPNTYFNAAIDMINVWKNRYQVTYEKFRQMINVSIEEFLKGLEGYNQDFYNKFIQIYPSLTSGGEFNPLQGIDVVEIYSDVASKIKDKGYKGIFVIYDEFSKFLEGSIDRNSAMEIKMLQDFAEKCNRSADKQIHIMLISHKNISNYVDRLPKEKVDAWKAVGDRYKTIEINNLSNQMYEIMSHVIIKERNSWERFISYNQDKFNSLILEMSRNAIFSELGQDLENTVVYGGYPLHPITTYILPKISEKVAQNERTIFTFLSTRQQNTLGHFLMNNKNDFPLMTPDYIYNYFETLFKKENYTSEIYKIWRDTTNALKKIGEKEKIEEKIIKCLGLIYIVGEFQKLPPTFEIIKLILSSTIEQGNLDTIIDSLLQRKILYHIKSKGYLKFIEATDVDVNALISDTIEKRKNLFSNKKVLNDNFYDNYIYATAYNDEHEIIRYFDFEFIEYRELAETSDWEKKIECKISDGIVYAVLIDNEENLVESKKIIRNIHHERIVFILPNQILQFKSLLQKYDAIEYLIGKNQYENQDKLLHEELNVHLDDVKEQILNYLDIFLKPELGAATYYYIGKEQKINRKSLLSRLISEICEKVYSHTPVIINELINKNEPTTVAINNRRKVLDGLLQNKVLPRLGLVGYGQDVTIMQSTLVVTGILREEADNEENKAYLCTKGLEPKIQNVIDTIRTFLIDTSKNGRMTFDKLYDKLTKPKWHIGLKKGIIPIYIAVLLHEFKKYAVISRNGYEMEITGRLLDDINDKPEEFEIYIENWDEQKEKYIQGLENIFKEYIVDGEKEYNTFEYIVRAIYRWFLQLPKYTKEYRKVYLGSSNFDNLDTHIIKLRNSLKGTRINSRDFLFDKLFKIFGYEDFNTNIILDIKQVKITLDNNKKYLIEHLALDIKKIFMKHYNEQVSLYSVMKDWYEGLDNYTKNNLFNLGEEKFLQEIKNITNDYISFIEKISKIITGLRVEDWNDQTIDKFINEVKKYKENIEKFNEELQQEGNEKVEQRSYKISFFTENGEEKTKTFEKVKLSDEAELMYNEIESIFDGYGESIDISEKRQILMKIFEKCC
>NZ_CP042243.1|WP_148808697.1|810432_811593_+|aminotransferase-class-V-fold-PLP-dependent-enzyme
MDNIIYFDNAATTYPKPEEVYTFMDKYYREFGVNVGRGQYTTASKANKIVEETRELIRELFKCSIDKKVIFTPSATEAINIILQGINWQGEENVYITHFEHNAVLRLLYQLKEKYNIKINFLHTEKKPLFYDIEKIKHQFQDIKPDVVIMTHASNVCGLITPIKEITELAKVYNAQVAIDCAQTAGLLDIDMKKIDADYLIFAGHKTLYGPFGIAGFLMDERSTLKPLLYGGTGIDSANPNLPNTIPEKFEVGSLNVYAIAGLNAALKWINKIGRENIYKKEKEMTTSLITCLESFDNIRVITASDAEKQIGVVSCVFEGYGSDIIGQVFDQYNIAVRTGLHCAPEAHRFLGTFPGGTVRLSLGYFNSKEDITKLHNILEYIYLDS
>NZ_CP042243.1|WP_168198227.1|811676_813824_+|DUF262-domain-containing-protein
MNLKEIFEKSDEDRLVLPDFQREFEWNKDAQKRLLSSFFVSIPIGSLLILEGKKDDFLSKKLCFAGETIEPTEECLYLLDGQQRVSSLRSTFYDFFQDKHNWLNIWEKMYSGLRNRWFLKIKPDNEEEDVFGWRMLNFKGLKYCEPSDLINCFEHRYIYKRKSTDWYHPGYKLYDKEGKELEGSRLKNKLAREAAKMGLVPLYSIYGSIKTTDKQLHTYVLEKIAKERVEELQAEVEDGKIDVFEIFQEIEPDIEEYIENNEIEKIRDAWSRLSAKWSESVNKFLVGLFEQEIPTIDLPSDQISRAIAIFENINKGGTPLDTFDLIVAKAARTKGERSLSQRISDYLEEEIDLSEALTNDLVDKVPDKWDSTLVMTIDENKITKTIKNQYLNLLSLFSHVPYGEVDKLKLEYIKRAKIFELTHEQINTNTNITLKALTRACAFLQIRCGLIDIKSLSYDLMILPIAYILKNDDVYEDKRALARIEYWYWSSLFSGAYRERQNEQCIKDIKNLFEWIKGGENKFKIRYENILNDIGYSDKTVLLRKDQEHNIPKAIHNGILQYILSKQPVDFLPNAQEKLRLNAWEIGGKKIIEIDGNKQTISVEDHHICPLGTVTKIGETSKKLRNDKKHILNSILNRTYISSIANAKISDKSPERYMKYVMDSAQWGHYLPIKMKEIFEEKGKSLEQKYEAILENRYNMLKRAIKEELDRLEDM
>NZ_CP042243.1|WP_148808699.1|814183_816373_+|DEAD/DEAH-box-helicase-family-protein
MSLQDIDIKDEYRSLIDNVVKDFYIPLLQKASEYKRAVGFFSSSALIEISKGIAGLAKNGGKILMVASPYLSDDDVEAIRKGYELRDKIIRRALVRELNEPKDLYEKDRLNLLANLVSDGILDIKIAFTEDKNKMGMYHEKMGIISDALGNKVAFSGSMNESATAMMINYETIDVFCSWKNQFENEKVNAKESTFTSIWTDCEPNIRIIDFPNLKQEIIDRYKKSTPNFNIDEQEFGERSVVLETKTKYRLGAVIPTNIKLYDYQIEAIDKWEKQDFKGIFDMATGTGKTFTGLGAVARLSEKLDDRLAVVIVCPYQHLVEQWVEDAKNFNIMPIIGYSNSPQKDWKKRLSTSVRNQKLKVRGRDFFTFICTNATFKSKIVQEQISKIKNNLLLVVDEAHNFGTEGIRNLLDDRFTYRLALSATLERHNDEEGTQKLYNYFGEKCIEYSLEQAIKEKKLTPYKYYPVVTTLTEDEREIYSKLSYEMSRNLIKGKNGKLKLSKYGEILALKRARIVAAAKEKIDVLREKIVPYKNDSYILVYCGIANVIDDNQDYSIVDECDLRQIDVVTNLLGNELNMKVSQFTSKEDIEERKILKEQFAKGEQLQALIAIKCLDEGVNIPKIKTAFILASTTNPKEYIQRRGRVLRRAEGKDFAEIYDFITLPRPLDEVSSLTIEEMKRDISLVQNEIVRMEEFGRISMNAMDSYSLIWEIRELYGLNDRDLEFIQDI
>NZ_CP042243.1|WP_168198228.1|816384_816549_+|hypothetical-protein
MANVNGIEIDEKKAQRLLKKLILMEKNNIRTKQNSDPDMVKKIKKMIEEEVGCY
>NZ_CP042243.1|WP_148808700.1|816539_818522_+|AAA-family-ATPase
MLLKSLKLSNFRQFRNEEVQFSTDSDKNVTIIIGENGTGKTTFSQAFFWCLYGDVDFKDKSMLNKIVASELTPDKSATVKVILSLIHAGTEYEIIREQVYKINYSGKLKGLNSTLNIQYKKNGQQEFLKPLEIEPRIKEILPKELSKYFFFDGERIEKMSKEIQSGRKSYEFAQAVRGLLGLSAFISALEHLKPTSKGVIGSYENSYDAKSNINIARYTDEIDKYKTQLEKIENRLKEIENEILKSEDRKKELEKIIQKYAEGEKLQNQKKNLINKRSSTLNSKRITIDKLLREFNDKASSYFARSMIKKSLEILGNGDFTNKDIPEMHAKTIDFLIKKGTCLCGTPLEVGSKEYNNILSLLQYLPPQSIGIAVGQFIKESQMRAKTSRDLFESYSSTLAVIEEQNDTIAAYDNEISLIEKNLVGIESVAPYQSELQICEKVIRDRTREKDELIEQRGSITTKKERANTERQALTLRDETNKKIEIYKAYAQYMYDEIKKVYKENENFTRKKLEDTINNIFKDIYQGGLSLTIDENYNIAVLVDDYEQFSNVETSTAQSIAVIFAFISGIIKMARESNTSNDERVKMLASEPYPLVMDAPLSAFDKRRIESVCKALPNIAEQVIIFIKDTDGDLAKEHMGEKIGKQYRFDKLNEFETVLN
>NZ_CP042243.1|WP_148808701.1|818533_819058_+|hypothetical-protein
MFDKEYSFKGSHAKKVNRLTGQFDEHSKSKIFSRNIDVYIVAPLIGFLYGRKSPLNNEDKESAKIMGDMIIKSAEDLKYNLRLILLLDEKYEPDEKERINRAFKFLGSEKTVKQDLELFESYVRGGVDVLYEKIMEPSNEYMNNLYDFLEEFDDRFNQTISDDSIVDLCKLARS
>NZ_CP042243.1|WP_148808702.1|819066_820146_+|sigma-70-family-RNA-polymerase-sigma-factor
MISDNKRSIILKNLQTLAKNKGYLTFDNILDISEKFDIKIDDVDRISESVLDSGIIIKDTDDEKEDKSNIDRSRIDYNEIYDKVLELDSTLKSYIKFIKKVPSPAVRELQHLIYQAKDGNKYAVSRIVYMYSKMVIKIALSFSEKLHLPIADTIQDGIVGLIYAIDKYDPSSEGGFATYAPWWIRQYIQREAKIINSLIYYPVYMKEKIFSIYDIVLEHICDKCLENGYCPRLLSQIQGKLECDLEQVVWFLNQLQEYYSIESLIGDNNEVFNDNNLFEDIMIENINRDILKDRISCTLLQFKERERKVIEKRFGFKNDIEMTLEEVGKEFGVTRERIRQIEYKVLKRLKHLSRRKRLK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP042243_2	2.11\|802563\|34\|NZ_CP042243\|CRISPRCasFinder	802563-802596	34	NZ_CP041069	Bacillus megaterium strain KNU-01 plasmid pKNU_01_5, complete sequence	47763-47796	5	0.853
NZ_CP042243_2	2.2\|802101\|33\|NZ_CP042243\|PILER-CR	802101-802133	33	AP013737	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C40-MedDCM-OCT-S36-C23, * SEQUENCING IN PROGRESS *	27054-27086	7	0.788
NZ_CP042243_2	2.2\|802101\|33\|NZ_CP042243\|PILER-CR	802101-802133	33	AP013445	Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-C40-MedDCM-OCT-S28-C16	35027-35059	7	0.788
NZ_CP042243_2	2.22\|802562\|36\|NZ_CP042243\|CRT	802562-802597	36	NZ_CP041069	Bacillus megaterium strain KNU-01 plasmid pKNU_01_5, complete sequence	47762-47797	7	0.806
NZ_CP042243_1	1.8\|179942\|36\|NZ_CP042243\|PILER-CR,CRISPRCasFinder,CRT	179942-179977	36	NZ_CP012484	Bacillus cereus strain NJ-W plasmid unnamed35-36, complete sequence	8772-8807	8	0.778
NZ_CP042243_1	1.10\|180070\|36\|NZ_CP042243\|PILER-CR,CRISPRCasFinder,CRT	180070-180105	36	NZ_CP017574	Bacillus thuringiensis strain SCG04-02 plasmid PSCG364, complete sequence	321716-321751	8	0.778
NZ_CP042243_2	2.4\|802098\|36\|NZ_CP042243\|CRISPRCasFinder	802098-802133	36	AP013737	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C40-MedDCM-OCT-S36-C23, * SEQUENCING IN PROGRESS *	27054-27089	8	0.778
NZ_CP042243_2	2.4\|802098\|36\|NZ_CP042243\|CRISPRCasFinder	802098-802133	36	AP013445	Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-C40-MedDCM-OCT-S28-C16	35027-35062	8	0.778
NZ_CP042243_1	1.1\|179492\|35\|NZ_CP042243\|PILER-CR,CRISPRCasFinder,CRT	179492-179526	35	MN693548	Marine virus AFVG_25M358, complete genome	34739-34773	9	0.743
NZ_CP042243_2	2.11\|802563\|34\|NZ_CP042243\|CRISPRCasFinder	802563-802596	34	NZ_CP053838	Aliiarcobacter faecis strain CCUG 66484 plasmid pAFAEC, complete sequence	18644-18677	9	0.735
NZ_CP042243_2	2.15\|802097\|38\|NZ_CP042243\|CRT	802097-802134	38	AP013737	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C40-MedDCM-OCT-S36-C23, * SEQUENCING IN PROGRESS *	27053-27090	9	0.763
NZ_CP042243_2	2.15\|802097\|38\|NZ_CP042243\|CRT	802097-802134	38	AP013445	Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-C40-MedDCM-OCT-S28-C16	35026-35063	9	0.763
NZ_CP042243_2	2.8\|802366\|35\|NZ_CP042243\|CRISPRCasFinder	802366-802400	35	KY554777	Lactococcus phage LW81, complete genome	102342-102376	10	0.714
NZ_CP042243_2	2.11\|802563\|34\|NZ_CP042243\|CRISPRCasFinder	802563-802596	34	NZ_CP011156	Bacillus cereus strain HN001 plasmid pRML01, complete sequence	88850-88883	10	0.706
NZ_CP042243_2	2.22\|802562\|36\|NZ_CP042243\|CRT	802562-802597	36	NZ_CP053838	Aliiarcobacter faecis strain CCUG 66484 plasmid pAFAEC, complete sequence	18643-18678	10	0.722
NZ_CP042243_2	2.19\|802365\|37\|NZ_CP042243\|CRT	802365-802401	37	KY554777	Lactococcus phage LW81, complete genome	102341-102377	12	0.676

1. spacer 2.11|802563|34|NZ_CP042243|CRISPRCasFinder matches to NZ_CP041069 (Bacillus megaterium strain KNU-01 plasmid pKNU_01_5, complete sequence) position: , mismatch: 5, identity: 0.853

tatattcttaaaattttatataac-aacaactata	CRISPR spacer
tatatttttaaaattttacataacaaataattat-	Protospacer
******.***********.***** **.**.***

2. spacer 2.2|802101|33|NZ_CP042243|PILER-CR matches to AP013737 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C40-MedDCM-OCT-S36-C23, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 7, identity: 0.788

tttactctcaataattcaacagaattaatattc	CRISPR spacer
gtatctctaaataattcaacagtattaatatct	Protospacer
 *  **** ************* ********..

3. spacer 2.2|802101|33|NZ_CP042243|PILER-CR matches to AP013445 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-C40-MedDCM-OCT-S28-C16) position: , mismatch: 7, identity: 0.788

tttactctcaataattcaacagaattaatattc	CRISPR spacer
gtatctctaaataattcaacagtattaatatct	Protospacer
 *  **** ************* ********..

4. spacer 2.22|802562|36|NZ_CP042243|CRT matches to NZ_CP041069 (Bacillus megaterium strain KNU-01 plasmid pKNU_01_5, complete sequence) position: , mismatch: 7, identity: 0.806

ttatattcttaaaattttatataac-aacaactatat	CRISPR spacer
gtatatttttaaaattttacataacaaataattatg-	Protospacer
 ******.***********.***** **.**.***.

5. spacer 1.8|179942|36|NZ_CP042243|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012484 (Bacillus cereus strain NJ-W plasmid unnamed35-36, complete sequence) position: , mismatch: 8, identity: 0.778

ttaaggaaaatatacaagatttaaaaactgcaaatg	CRISPR spacer
cgaaggaaaatatagaagaattaaaaacaataaaag	Protospacer
. ************ **** ******** ..*** *

6. spacer 1.10|180070|36|NZ_CP042243|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017574 (Bacillus thuringiensis strain SCG04-02 plasmid PSCG364, complete sequence) position: , mismatch: 8, identity: 0.778

attttaggttcaaattcaattgtaaatggaaaatat	CRISPR spacer
tttttaggttcaaatacatttgtaaatactacatct	Protospacer
 ************** ** ********.  * ** *

7. spacer 2.4|802098|36|NZ_CP042243|CRISPRCasFinder matches to AP013737 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C40-MedDCM-OCT-S36-C23, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 8, identity: 0.778

ttttttactctcaataattcaacagaattaatattc	CRISPR spacer
ttagtatctctaaataattcaacagtattaatatct	Protospacer
**  *  **** ************* ********..

8. spacer 2.4|802098|36|NZ_CP042243|CRISPRCasFinder matches to AP013445 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-C40-MedDCM-OCT-S28-C16) position: , mismatch: 8, identity: 0.778

ttttttactctcaataattcaacagaattaatattc	CRISPR spacer
ttagtatctctaaataattcaacagtattaatatct	Protospacer
**  *  **** ************* ********..

9. spacer 1.1|179492|35|NZ_CP042243|PILER-CR,CRISPRCasFinder,CRT matches to MN693548 (Marine virus AFVG_25M358, complete genome) position: , mismatch: 9, identity: 0.743

ataggttcggtaaaaattttaaatgcaaatgaaag	CRISPR spacer
gtaacaacagtaaaaattttaaatgcaaacgtaac	Protospacer
.**.   *.********************.* **

10. spacer 2.11|802563|34|NZ_CP042243|CRISPRCasFinder matches to NZ_CP053838 (Aliiarcobacter faecis strain CCUG 66484 plasmid pAFAEC, complete sequence) position: , mismatch: 9, identity: 0.735

tatattcttaaaattttatataacaacaactata	CRISPR spacer
caagaattaaaaattttaaagaacaacaactata	Protospacer
.* .  .* ********* * *************

11. spacer 2.15|802097|38|NZ_CP042243|CRT matches to AP013737 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C40-MedDCM-OCT-S36-C23, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.763

attttttactctcaataattcaacagaattaatattcg	CRISPR spacer
attagtatctctaaataattcaacagtattaatatcta	Protospacer
***  *  **** ************* ********...

12. spacer 2.15|802097|38|NZ_CP042243|CRT matches to AP013445 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-C40-MedDCM-OCT-S28-C16) position: , mismatch: 9, identity: 0.763

attttttactctcaataattcaacagaattaatattcg	CRISPR spacer
attagtatctctaaataattcaacagtattaatatcta	Protospacer
***  *  **** ************* ********...

13. spacer 2.8|802366|35|NZ_CP042243|CRISPRCasFinder matches to KY554777 (Lactococcus phage LW81, complete genome) position: , mismatch: 10, identity: 0.714

tttatttgatttatctattgcccctattgttatta	CRISPR spacer
cattgctgatgtatctattgcccctatttttagat	Protospacer
. *  .**** ***************** ***

14. spacer 2.11|802563|34|NZ_CP042243|CRISPRCasFinder matches to NZ_CP011156 (Bacillus cereus strain HN001 plasmid pRML01, complete sequence) position: , mismatch: 10, identity: 0.706

tatattcttaaaattttatataacaacaactata	CRISPR spacer
cctaaaacaaaaattttatataactacaaccatt	Protospacer
. **   . *************** *****.**

15. spacer 2.22|802562|36|NZ_CP042243|CRT matches to NZ_CP053838 (Aliiarcobacter faecis strain CCUG 66484 plasmid pAFAEC, complete sequence) position: , mismatch: 10, identity: 0.722

ttatattcttaaaattttatataacaacaactatat	CRISPR spacer
ccaagaattaaaaattttaaagaacaacaactatat	Protospacer
..* .  .* ********* * **************

16. spacer 2.19|802365|37|NZ_CP042243|CRT matches to KY554777 (Lactococcus phage LW81, complete genome) position: , mismatch: 12, identity: 0.676

ttttatttgatttatctattgcccctattgttattac	CRISPR spacer
ccattgctgatgtatctattgcccctatttttagatt	Protospacer
.. *  .**** ***************** ***   .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

963019 : 973378

Lactobacillus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_148808807.1\|963019_963388_-	DUF898 family protein	S5MNN8	Brevibacillus_phage	1.6e-17	67.2
WP_148808808.1\|963893_964244_-	helix-turn-helix domain-containing protein	A0A0P0IZG9	Lactobacillus_phage	1.5e-14	38.4
WP_148808809.1\|964408_964645_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_168198235.1\|964708_964864_+	hypothetical protein	NA	NA	NA	NA
WP_168198236.1\|964868_965027_+	hypothetical protein	NA	NA	NA	NA
WP_168198237.1\|965016_965187_-	hypothetical protein	NA	NA	NA	NA
WP_148808810.1\|965291_965489_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_148808811.1\|965543_965726_+	hypothetical protein	NA	NA	NA	NA
WP_148808812.1\|965722_966463_+	Rha family transcriptional regulator	R9QMZ3	Lactococcus_phage	2.0e-43	41.6
WP_148808813.1\|966475_967258_+	hypothetical protein	A0A075KK42	Lactobacillus_phage	1.1e-84	63.1
WP_148808814.1\|967280_967532_+	excisionase family DNA-binding protein	NA	NA	NA	NA
WP_148808815.1\|967594_967831_+	hypothetical protein	NA	NA	NA	NA
WP_148808816.1\|967835_967964_-	hypothetical protein	NA	NA	NA	NA
WP_148808817.1\|968189_968330_+	Spo0E family sporulation regulatory protein-aspartic acid phosphatase	NA	NA	NA	NA
WP_148808818.1\|968326_968626_+	hypothetical protein	NA	NA	NA	NA
WP_148808819.1\|968737_969220_+	siphovirus Gp157 family protein	E5DV79	Deep-sea_thermophilic_phage	1.4e-29	45.3
WP_148808820.1\|969358_970330_+	hypothetical protein	A0A088FAU5	Sulfitobacter_phage	7.7e-64	43.6
WP_148808821.1\|970373_970973_+	recombinase	J9QD21	Clostridium_phage	4.6e-59	60.8
WP_168198238.1\|972005_972149_+	hypothetical protein	NA	NA	NA	NA
WP_148808822.1\|972145_972325_+	hypothetical protein	NA	NA	NA	NA
WP_148808823.1\|972324_972750_+	hypothetical protein	NA	NA	NA	NA
WP_148808824.1\|972742_973378_+	hypothetical protein	D7RWH3	Brochothrix_phage	6.0e-41	41.6

DBSCAN-SWA_2

977717 : 1003962

Clostridium_phage(46.15%)

holin,terminase,coat,tail,plate,capsid,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_148808831.1\|977717_977906_+	hypothetical protein	A0A0A7S0P6	Clostridium_phage	9.1e-14	58.2
WP_168198241.1\|977911_978073_+	hypothetical protein	NA	NA	NA	NA
WP_148808832.1\|978187_978553_+	single-stranded DNA-binding protein	U3PBI4	Lactobacillus_phage	4.1e-18	44.3
WP_148808833.1\|978573_979098_+	hypothetical protein	NA	NA	NA	NA
WP_148808834.1\|979832_980015_+	hypothetical protein	NA	NA	NA	NA
WP_148808835.1\|980098_980272_-	Spo0E family sporulation regulatory protein-aspartic acid phosphatase	NA	NA	NA	NA
WP_148808836.1\|980523_981351_+	hypothetical protein	Q5G8R0	Enterobacteria_phage	7.4e-07	29.8
WP_148808837.1\|981381_982266_+\|terminase	terminase	A0A0A7RTY1	Clostridium_phage	4.5e-79	53.6
WP_148808838.1\|982258_983512_+\|terminase	PBSX family phage terminase large subunit	A0A0K2CP71	Brevibacillus_phage	1.4e-163	69.6
WP_168198242.1\|983526_984966_+\|portal	phage portal protein	X5J9Z4	Clostridium_phage	2.6e-100	43.2
WP_148808840.1\|984958_986554_+\|capsid	minor capsid protein	A0A0A7RVY7	Clostridium_phage	6.0e-90	42.3
WP_148808841.1\|986559_986793_+	hypothetical protein	NA	NA	NA	NA
WP_148808842.1\|986931_987594_+	hypothetical protein	A0A0K2CP96	Brevibacillus_phage	6.7e-11	30.3
WP_148808843.1\|987610_988768_+\|coat	P22 coat protein	A0A2H5BLD0	Streptomyces_phage	4.3e-21	31.6
WP_148808844.1\|988812_989028_+	hypothetical protein	Q4ZC68	Staphylococcus_virus	1.4e-05	70.3
WP_148808845.1\|989027_989324_+	hypothetical protein	A0A0A7RTF6	Clostridium_phage	4.5e-07	30.3
WP_148808846.1\|989320_989677_+	hypothetical protein	NA	NA	NA	NA
WP_148808847.1\|989676_990066_+	HK97 gp10 family phage protein	Q708M3	Streptococcus_phage	1.9e-05	35.9
WP_148808848.1\|990078_990600_+	hypothetical protein	A0A0A8WFA6	Clostridium_phage	7.4e-13	37.8
WP_148808849.1\|990600_991662_+\|tail	phage tail sheath protein	A0A0A8WJR2	Clostridium_phage	5.6e-84	51.4
WP_148808850.1\|991674_992112_+\|terminase	terminase	A0A0A8WF55	Clostridium_phage	1.6e-29	50.0
WP_148808851.1\|992125_992527_+	hypothetical protein	A0A0A8WIB2	Clostridium_phage	1.9e-21	43.6
WP_148808852.1\|992719_993013_+	hypothetical protein	NA	NA	NA	NA
WP_148808853.1\|993059_994841_+	hypothetical protein	A0A1U9WQS5	Geobacillus_phage	4.3e-44	33.2
WP_168198243.1\|994895_995063_+	hypothetical protein	NA	NA	NA	NA
WP_148808854.1\|995098_995518_+	hypothetical protein	A0A0A8WJR4	Clostridium_phage	1.4e-17	32.9
WP_148808855.1\|995519_996500_+	hypothetical protein	NA	NA	NA	NA
WP_148808856.1\|996499_996916_+	DUF2577 family protein	NA	NA	NA	NA
WP_148808857.1\|996915_997362_+	DUF2634 domain-containing protein	A0A1V0DZX2	Clostridioides_phage	7.2e-09	33.1
WP_148808858.1\|997362_998406_+\|plate	baseplate J/gp47 family protein	A0A0A7RUN3	Clostridium_phage	1.8e-66	43.8
WP_148810760.1\|998413_998944_+	DUF2313 domain-containing protein	S6BFJ0	Thermus_phage	1.1e-32	45.4
WP_148808859.1\|1000106_1000490_+	hypothetical protein	NA	NA	NA	NA
WP_148808860.1\|1000540_1001536_+	S8 family serine peptidase	A0A127AWU5	Bacillus_phage	1.3e-21	31.9
WP_148808861.1\|1001548_1001986_+	DUF882 domain-containing protein	A0A2I7RQ68	Vibrio_phage	1.6e-16	41.2
WP_148808862.1\|1001993_1002218_+	hypothetical protein	A0A0A7RWP8	Clostridium_phage	6.8e-16	56.8
WP_148808863.1\|1002230_1002530_+\|holin	holin	A0A2H4JAH4	uncultured_Caudovirales_phage	3.1e-08	39.1
WP_148808864.1\|1002921_1003122_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_148808865.1\|1003350_1003962_+	sce7726 family protein	A0A0U2RXY7	Escherichia_phage	1.7e-32	41.6

DBSCAN-SWA_3

1202855 : 1208780

Paenibacillus_phage(66.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_148809047.1\|1202855_1205090_+	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	7.5e-171	44.1
WP_168198393.1\|1205103_1205808_+	pyruvate formate lyase-activating protein	A0A1B1IXI7	Citrobacter_phage	1.3e-07	43.8
WP_148809049.1\|1205955_1206684_+	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_148809050.1\|1206907_1207108_+	small, acid-soluble spore protein, alpha/beta type	NA	NA	NA	NA
WP_148809051.1\|1207197_1207404_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_148809052.1\|1207591_1207789_+	helix-turn-helix domain-containing protein	A0A0C5AJ29	Paenibacillus_phage	7.8e-16	63.5
WP_148810771.1\|1208012_1208369_+\|transposase	IS3 family transposase	A0A0C5AEA5	Paenibacillus_phage	3.6e-35	72.4
WP_148809053.1\|1208310_1208553_+	hypothetical protein	A0A0C5AEA5	Paenibacillus_phage	8.4e-20	79.3
WP_148809054.1\|1208534_1208780_+\|transposase	IS3 family transposase	A0A0C5AEA5	Paenibacillus_phage	9.7e-32	79.0

DBSCAN-SWA_4

1925932 : 1960878

Caldibacillus_phage(19.05%)

terminase,tail,protease,plate,tRNA,capsid,portal,head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_148809706.1\|1925932_1928593_-\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	2.5e-181	44.9
WP_148809707.1\|1928583_1928802_-	hypothetical protein	NA	NA	NA	NA
WP_148809708.1\|1929149_1929494_-	hypothetical protein	NA	NA	NA	NA
WP_148809709.1\|1929622_1930054_+	hypothetical protein	NA	NA	NA	NA
WP_168198302.1\|1930055_1930196_-	hypothetical protein	NA	NA	NA	NA
WP_148810816.1\|1930401_1931148_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_148809710.1\|1931216_1933397_-	hypothetical protein	A0A2H4J056	uncultured_Caudovirales_phage	1.2e-64	26.8
WP_148809711.1\|1933406_1933619_-	hypothetical protein	NA	NA	NA	NA
WP_148809712.1\|1933957_1934218_-	hypothetical protein	NA	NA	NA	NA
WP_148809713.1\|1934214_1935126_-	ParM/StbA family protein	G3MAP7	Bacillus_virus	2.8e-23	26.4
WP_148809714.1\|1935260_1935464_-	helix-turn-helix domain-containing protein	A0A2H4J765	uncultured_Caudovirales_phage	5.2e-07	52.9
WP_148809715.1\|1936302_1936728_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_148809716.1\|1936758_1937064_-	DUF4325 domain-containing protein	NA	NA	NA	NA
WP_148809717.1\|1937075_1938020_-	ATP-binding protein	NA	NA	NA	NA
WP_148809718.1\|1938307_1938508_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_148809719.1\|1938898_1939105_-	hypothetical protein	NA	NA	NA	NA
WP_148809720.1\|1939109_1939328_-	hypothetical protein	NA	NA	NA	NA
WP_168198303.1\|1939336_1939843_-	N-acetylmuramoyl-L-alanine amidase	A0A0F7LBB1	uncultured_marine_virus	2.7e-12	40.0
WP_148809722.1\|1939955_1940360_-	hypothetical protein	NA	NA	NA	NA
WP_148809723.1\|1940376_1940778_-	hypothetical protein	NA	NA	NA	NA
WP_148809724.1\|1941082_1941409_-	hypothetical protein	NA	NA	NA	NA
WP_148809725.1\|1941409_1941946_-	DUF2313 domain-containing protein	S6BFJ0	Thermus_phage	1.2e-31	41.4
WP_148809726.1\|1941938_1942982_-\|plate	baseplate J/gp47 family protein	A0A0A7RUN3	Clostridium_phage	2.6e-65	44.1
WP_148809727.1\|1942982_1943435_-	DUF2634 domain-containing protein	A0A1V0DZX2	Clostridioides_phage	3.6e-08	40.9
WP_148809728.1\|1943448_1943895_-	DUF2577 family protein	NA	NA	NA	NA
WP_148809729.1\|1943894_1944893_-	hypothetical protein	NA	NA	NA	NA
WP_148809730.1\|1944894_1945314_-\|portal	phage portal protein	NA	NA	NA	NA
WP_148809731.1\|1945317_1947312_-\|tail	phage tail tape measure protein	A0A0U4IIN6	Exiguobacterium_phage	2.2e-36	37.4
WP_148809732.1\|1947510_1947939_-	hypothetical protein	NA	NA	NA	NA
WP_148809733.1\|1948007_1948439_-	hypothetical protein	NA	NA	NA	NA
WP_148809734.1\|1948459_1949551_-\|tail	phage tail sheath protein	A0A090D804	Clostridium_phage	2.9e-35	31.1
WP_148809735.1\|1949574_1950018_-	hypothetical protein	NA	NA	NA	NA
WP_148809736.1\|1950029_1950467_-	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_148809737.1\|1950466_1950796_-\|head	phage head closure protein	NA	NA	NA	NA
WP_148809738.1\|1950792_1951074_-	DNA-packaging protein	A0A1L2BY95	Clostridium_phage	5.5e-31	75.3
WP_148809739.1\|1951076_1951370_-	hypothetical protein	A0A290GHN0	Caldibacillus_phage	9.9e-07	60.9
WP_148809740.1\|1951386_1952643_-\|capsid	phage major capsid protein	A0A290FZS5	Caldibacillus_phage	7.2e-147	63.7
WP_148809741.1\|1952635_1953349_-\|protease	Clp protease ClpP	R9TLM7	Paenibacillus_phage	7.6e-85	68.8
WP_148809742.1\|1953363_1954509_-\|portal	phage portal protein	R9TLS1	Paenibacillus_phage	9.4e-154	77.2
WP_148809743.1\|1954521_1956228_-\|terminase	terminase large subunit	A0A290GJW3	Caldibacillus_phage	2.8e-255	74.2
WP_148810817.1\|1956224_1956626_-	hypothetical protein	A0A290GJQ7	Caldibacillus_phage	5.8e-34	62.9
WP_148809744.1\|1956693_1956993_-	HNH endonuclease	R9TNN2	Paenibacillus_phage	7.2e-29	66.0
WP_168198304.1\|1957023_1957701_-	hypothetical protein	Q5G8R0	Enterobacteria_phage	1.2e-07	36.4
WP_148809746.1\|1957666_1957858_-	hypothetical protein	NA	NA	NA	NA
WP_148808835.1\|1958110_1958284_+	Spo0E family sporulation regulatory protein-aspartic acid phosphatase	NA	NA	NA	NA
WP_148808834.1\|1958367_1958550_-	hypothetical protein	NA	NA	NA	NA
WP_148809747.1\|1959270_1959792_-	hypothetical protein	NA	NA	NA	NA
WP_148809748.1\|1959811_1960183_-	single-stranded DNA-binding protein	U3PBI4	Lactobacillus_phage	3.2e-18	45.3
WP_168198305.1\|1960297_1960459_-	hypothetical protein	NA	NA	NA	NA
WP_148809749.1\|1960503_1960878_-	hypothetical protein	A0A0K1LKF1	Vibrio_phage	3.7e-14	38.4

DBSCAN-SWA_5

2022041 : 2066911

Clostridium_phage(23.08%)

protease,tail,transposase,plate,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_148809826.1\|2022041_2023094_-\|protease	trypsin-like serine protease	A0A1B1IT49	uncultured_Mediterranean_phage	8.5e-16	29.1
WP_148809827.1\|2023206_2023896_-	RDD family protein	NA	NA	NA	NA
WP_168198312.1\|2023945_2024890_+	stage II sporulation protein M	NA	NA	NA	NA
WP_148809829.1\|2024891_2026202_-	DUF58 domain-containing protein	NA	NA	NA	NA
WP_148809830.1\|2026215_2027169_-	AAA domain-containing protein	NA	NA	NA	NA
WP_148809831.1\|2027138_2028161_-	hypothetical protein	NA	NA	NA	NA
WP_148809832.1\|2028147_2028780_-	hypothetical protein	NA	NA	NA	NA
WP_148809833.1\|2028792_2029764_-	hypothetical protein	NA	NA	NA	NA
WP_148809834.1\|2029937_2030318_-	DUF3221 domain-containing protein	NA	NA	NA	NA
WP_148809835.1\|2030490_2033091_-	bifunctional acetaldehyde-CoA/alcohol dehydrogenase	NA	NA	NA	NA
WP_148809836.1\|2033473_2034229_-	VCBS repeat-containing protein	NA	NA	NA	NA
WP_148809837.1\|2034293_2034659_-	TIGR03987 family protein	NA	NA	NA	NA
WP_148809838.1\|2034819_2035446_+	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	2.7e-33	39.8
WP_148809839.1\|2035723_2036584_-	hypothetical protein	X5JAW1	Clostridium_phage	1.7e-35	39.8
WP_168198313.1\|2036706_2036883_-	hypothetical protein	NA	NA	NA	NA
WP_148809840.1\|2037022_2037247_-	hypothetical protein	NA	NA	NA	NA
WP_148809841.1\|2037370_2037538_-	4Fe-4S binding protein	NA	NA	NA	NA
WP_148809842.1\|2037621_2038404_-	hypothetical protein	NA	NA	NA	NA
WP_148809843.1\|2038525_2039047_-	DUF4065 domain-containing protein	NA	NA	NA	NA
WP_148809844.1\|2039319_2039745_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_148809716.1\|2039775_2040081_-	DUF4325 domain-containing protein	NA	NA	NA	NA
WP_148809845.1\|2040092_2040788_-	ATP-binding protein	NA	NA	NA	NA
WP_168198314.1\|2040869_2041046_-	hypothetical protein	NA	NA	NA	NA
WP_148809718.1\|2041333_2041534_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_148809719.1\|2041933_2042140_-	hypothetical protein	NA	NA	NA	NA
WP_148809720.1\|2042144_2042363_-	hypothetical protein	Q0SPG4	Clostridium_phage	2.1e-06	41.7
WP_148809846.1\|2042371_2042935_-	N-acetylmuramoyl-L-alanine amidase	A0A0F7LBB1	uncultured_marine_virus	1.1e-17	40.2
WP_148809722.1\|2042988_2043393_-	hypothetical protein	NA	NA	NA	NA
WP_148809847.1\|2043409_2044693_-	hypothetical protein	Q9G0H9	Roseobacter_virus	3.2e-09	48.8
WP_148809848.1\|2044705_2045263_-	DUF2313 domain-containing protein	S6BFJ0	Thermus_phage	6.0e-21	40.9
WP_148809849.1\|2045252_2046320_-\|plate	baseplate J/gp47 family protein	F6MIL6	Haemophilus_phage	3.7e-35	32.6
WP_148809850.1\|2046316_2046667_-	DUF2634 domain-containing protein	NA	NA	NA	NA
WP_148809851.1\|2046679_2047165_-	hypothetical protein	NA	NA	NA	NA
WP_148809852.1\|2047164_2048169_-	hypothetical protein	NA	NA	NA	NA
WP_148809853.1\|2048178_2048760_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_148809854.1\|2049075_2049825_-	hypothetical protein	M1PKL6	Streptococcus_phage	1.1e-33	58.0
WP_148809855.1\|2049943_2050126_-	hypothetical protein	NA	NA	NA	NA
WP_148810819.1\|2050278_2050668_-	hypothetical protein	A0A0M5M1L9	Bacillus_phage	2.1e-28	56.3
WP_168198315.1\|2050870_2051518_-	Rha family transcriptional regulator	X5JAX3	Clostridium_phage	5.0e-19	43.1
WP_148809857.1\|2051548_2051782_-	XRE family transcriptional regulator	NA	NA	NA	NA
WP_148809858.1\|2051904_2052399_+	hypothetical protein	NA	NA	NA	NA
WP_148809859.1\|2052948_2053716_-	DUF4339 domain-containing protein	NA	NA	NA	NA
WP_148809860.1\|2053873_2056201_-\|tail	phage tail tape measure protein	R9TF76	Synechococcus_phage	9.0e-10	23.4
WP_148809861.1\|2056209_2056398_-	hypothetical protein	NA	NA	NA	NA
WP_148809862.1\|2056394_2056880_-	hypothetical protein	NA	NA	NA	NA
WP_148810820.1\|2057064_2058261_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	D2XQ03	Bacillus_virus	3.3e-109	51.5
WP_148809863.1\|2058518_2058917_-	hypothetical protein	NA	NA	NA	NA
WP_148809864.1\|2058929_2060036_-	hypothetical protein	NA	NA	NA	NA
WP_148809865.1\|2060040_2060589_-	hypothetical protein	NA	NA	NA	NA
WP_148809866.1\|2060593_2060785_-	hypothetical protein	NA	NA	NA	NA
WP_168198316.1\|2060794_2061214_-	hypothetical protein	NA	NA	NA	NA
WP_148809868.1\|2061215_2061677_-	hypothetical protein	NA	NA	NA	NA
WP_148809869.1\|2061669_2062050_-	hypothetical protein	NA	NA	NA	NA
WP_148809870.1\|2062086_2063130_-\|capsid	phage major capsid protein	NA	NA	NA	NA
WP_148809871.1\|2063156_2063522_-	hypothetical protein	NA	NA	NA	NA
WP_148809872.1\|2063536_2064763_-	hypothetical protein	NA	NA	NA	NA
WP_148809873.1\|2064784_2066911_-\|capsid	minor capsid protein	NA	NA	NA	NA

DBSCAN-SWA_6

2417255 : 2428024

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_148810161.1\|2417255_2418797_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	6.9e-67	45.6
WP_148810844.1\|2418808_2419423_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.9e-21	36.6
WP_148810162.1\|2419419_2420460_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	2.4e-71	45.0
WP_148810163.1\|2420471_2421887_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.2e-62	34.9
WP_148810164.1\|2421910_2422615_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3FUQ7	Synechococcus_phage	9.0e-38	36.4
WP_148810165.1\|2422635_2423118_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.1e-30	51.0
WP_168198342.1\|2423283_2424618_-	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	1.3e-48	32.9
WP_148810846.1\|2425063_2426092_-	P1 family peptidase	NA	NA	NA	NA
WP_148810847.1\|2426192_2426924_-	C26 family cysteine hydrolase domain-containing family	A0A2P9FI75	Pseudomonas_phage	2.0e-08	33.1
WP_148810166.1\|2427055_2428024_-	dipeptide ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	9.2e-17	30.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP042244

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP042243

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection