CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_AP019831	Leptotrichia trevisanii strain JMUB3870	6 crisprs	cas3,RT,csa3,PD-DExK,DinG,DEDDh,cas6,cas8b2,cas7,cas5,cas4,cas1,cas2,WYL,cas10,csx10gr5,csm3gr7,csx20,csx1	5	11	4	2
NZ_AP019833	Leptotrichia trevisanii strain JMUB3870 plasmid pJMUB3870-2, complete sequence	0 crisprs	NA	0	0	0	0
NZ_AP019832	Leptotrichia trevisanii strain JMUB3870 plasmid pJMUB3870-1, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_AP019831_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019831_1

1140716-1142569

Unclear

Consensus_repeat	Method
ATTTACAATACAAATTGTGCTATTAAAAT	CRISPRCasFinder
ATTTACAATACAAATTGTGCTATTAAAAT	CRT
ATTTACAATACAAATTGTGCTATTAAAAT	PILER-CR

28 spacers

cas6,cas8b2,cas7,cas5,cas3,cas4,cas1,cas2

The CRISPR arrays of NZ_AP019831_1

>merge|NZ_AP019831|1|1140716-1142569|CRISPRCasFinder,CRT,PILER-CR
ACTTTAAATACAAAATGTTCTATTAAAATCACTCCCATTGATTCTGCTATTTTTTGAGCCAAAATATTTACAATACAAATTGTGCTATTAAAATCTTTGCAATATCTCCAACTTATATTACAGAGCCACATTTACAATACAAATTGTGCTATTAAAATAAAGGGAATATCAAACTTTATCGGCGAACAGCTTAAATTTACAATACAAATTGTGCTATTAAAATAGTTTGAATACATTGATACTTATGTTAAATTGAAAGATTTACAATACAAATTGTGCTATTAAAATCATCATCATCATTTAACTTGATTGCACGTTTTCCAGCATTTACAATACAAATTGTGCTATTAAAATAATCTTTAATATTTCCAAGTAGCCTATACCGTCCTTCATTTACAATACAAATTGTGCTATTAAAATATATAATTTTTCCGTTTCCCAACAAGTTTTAATTAAATTTACAATACAAATTGTGCTATTAAAATTAACACAGAAAAAGTTATTAAATTAAGTTATCAAAGATTTACAATACAAATTGTGCTATTAAAATGAATTTGTAAGTGAAGTTATGAAAAAAGATAAGGATATTTACAATACAAATTGTGCTATTAAAATGAATTTGTAAGTGAAGTTATGAAAAAAGATAAGGATATTTACAATACAAATTGTGCTATTAAAATTTTAATGTAGATGAAATAAATCCTATTGTAATGAAATATTTACAATACAAATTGTGCTATTAAAATTCAACAATATGCAGATAGAATTGAATTTTTTGACGAGATTTACAATACAAATTGTGCTATTAAAATGATGGTGTATTGGAAAATAAAACAAGCAAGGAAAAAATTTACAATACAAATTGTGCTATTAAAATAGAAACTTTATATCAAGCACAGTGGCAAGAATATAAATTTACAATACAAATTGTGCTATTAAAATTGTTGAAAGTTTTGGATCAGGATATTATTACGAAAAATTTACAATACAAATTGTGCTATTAAAATTTAAAAGATTGCGTTATATCGAGTTATATTGATACGAATTTACAATACAAATTGTGCTATTAAAATCAAGATTCGGAAAAGATTTTGCTGGGAGCATTTTCTACATTTACAATACAAATTGTGCTATTAAAATATTAACTTAATTAATGTATTTACAAAATCTTTACTAATTTACAATACAAATTGTGCTATTAAAATAAGAAGAAACAGAAGCGATTAATATGTCAAGAGAAAATTTACAATACAAATTGTGCTATTAAAATTATTTGTACCTACTGTTCCTTTTGCTTGTTTTTTAATTTACAATACAAATTGTGCTATTAAAATATGACACCGCTCAAAGAAATATACGAAGATGTAAAAATTTACAATACAAATTGTGCTATTAAAATGTTTATTATAGATTTCTAGCCCCATTATAAAGGCTTATTTACAATACAAATTGTGCTATTAAAATAGATTTTTCTTTAGACGTGGCTTTTGGACTGGATTTATTTACAATACAAATTGTGCTATTAAAATGGAGTTGGAACGAAATAACAACTTCTTTGCAAAGCGATTTACAATACAAATTGTGCTATTAAAATCTCCAAGCGAAGTATTTTTAGTAATTCCGAAAGACGATTTACAATACAAATTGTGCTATTAAAATCGAAAAGATGTTTATTTTTTTCAGAAAAATTATAAAATTTACAATACAAATTGTGCTATTAAAATTGTATAATTGCGTATCCGAAATTCCCACAGACTTTGATTTACAATACAAATTGTGCTATTAAAATCATAACAATATTTCCTTTCTAAATTATATATTCTCAATTTACAATACAAATTGTGCTATTAAAAT

>NZ_AP019831|1|1|1140716-1142569|CRISPRCasFinder
ACTTTAAATACAAAATGTTCTATTAAAAT	CACTCCCATTGATTCTGCTATTTTTTGAGCCAAAAT
ATTTACAATACAAATTGTGCTATTAAAAT	CTTTGCAATATCTCCAACTTATATTACAGAGCCAC
ATTTACAATACAAATTGTGCTATTAAAAT	AAAGGGAATATCAAACTTTATCGGCGAACAGCTTAA
ATTTACAATACAAATTGTGCTATTAAAAT	AGTTTGAATACATTGATACTTATGTTAAATTGAAAG
ATTTACAATACAAATTGTGCTATTAAAAT	CATCATCATCATTTAACTTGATTGCACGTTTTCCAGC
ATTTACAATACAAATTGTGCTATTAAAAT	AATCTTTAATATTTCCAAGTAGCCTATACCGTCCTTC
ATTTACAATACAAATTGTGCTATTAAAAT	ATATAATTTTTCCGTTTCCCAACAAGTTTTAATTAA
ATTTACAATACAAATTGTGCTATTAAAAT	TAACACAGAAAAAGTTATTAAATTAAGTTATCAAAG
ATTTACAATACAAATTGTGCTATTAAAAT	GAATTTGTAAGTGAAGTTATGAAAAAAGATAAGGAT
ATTTACAATACAAATTGTGCTATTAAAAT	GAATTTGTAAGTGAAGTTATGAAAAAAGATAAGGAT
ATTTACAATACAAATTGTGCTATTAAAAT	TTTAATGTAGATGAAATAAATCCTATTGTAATGAAAT
ATTTACAATACAAATTGTGCTATTAAAAT	TCAACAATATGCAGATAGAATTGAATTTTTTGACGAG
ATTTACAATACAAATTGTGCTATTAAAAT	GATGGTGTATTGGAAAATAAAACAAGCAAGGAAAAA
ATTTACAATACAAATTGTGCTATTAAAAT	AGAAACTTTATATCAAGCACAGTGGCAAGAATATAA
ATTTACAATACAAATTGTGCTATTAAAAT	TGTTGAAAGTTTTGGATCAGGATATTATTACGAAAA
ATTTACAATACAAATTGTGCTATTAAAAT	TTAAAAGATTGCGTTATATCGAGTTATATTGATACGA
ATTTACAATACAAATTGTGCTATTAAAAT	CAAGATTCGGAAAAGATTTTGCTGGGAGCATTTTCTAC
ATTTACAATACAAATTGTGCTATTAAAAT	ATTAACTTAATTAATGTATTTACAAAATCTTTACTA
ATTTACAATACAAATTGTGCTATTAAAAT	AAGAAGAAACAGAAGCGATTAATATGTCAAGAGAAA
ATTTACAATACAAATTGTGCTATTAAAAT	TATTTGTACCTACTGTTCCTTTTGCTTGTTTTTTA
ATTTACAATACAAATTGTGCTATTAAAAT	ATGACACCGCTCAAAGAAATATACGAAGATGTAAAA
ATTTACAATACAAATTGTGCTATTAAAAT	GTTTATTATAGATTTCTAGCCCCATTATAAAGGCTT
ATTTACAATACAAATTGTGCTATTAAAAT	AGATTTTTCTTTAGACGTGGCTTTTGGACTGGATTT
ATTTACAATACAAATTGTGCTATTAAAAT	GGAGTTGGAACGAAATAACAACTTCTTTGCAAAGCG
ATTTACAATACAAATTGTGCTATTAAAAT	CTCCAAGCGAAGTATTTTTAGTAATTCCGAAAGACG
ATTTACAATACAAATTGTGCTATTAAAAT	CGAAAAGATGTTTATTTTTTTCAGAAAAATTATAAA
ATTTACAATACAAATTGTGCTATTAAAAT	TGTATAATTGCGTATCCGAAATTCCCACAGACTTTG
ATTTACAATACAAATTGTGCTATTAAAAT	CATAACAATATTTCCTTTCTAAATTATATATTCTCA
ATTTACAATACAAATTGTGCTATTAAAAT

>NZ_AP019831|1|1|1140716-1142569|CRT
ACTTTAAATACAAAATGTTCTATTAAAAT	CACTCCCATTGATTCTGCTATTTTTTGAGCCAAAAT
ATTTACAATACAAATTGTGCTATTAAAAT	CTTTGCAATATCTCCAACTTATATTACAGAGCCAC
ATTTACAATACAAATTGTGCTATTAAAAT	AAAGGGAATATCAAACTTTATCGGCGAACAGCTTAA
ATTTACAATACAAATTGTGCTATTAAAAT	AGTTTGAATACATTGATACTTATGTTAAATTGAAAG
ATTTACAATACAAATTGTGCTATTAAAAT	CATCATCATCATTTAACTTGATTGCACGTTTTCCAGC
ATTTACAATACAAATTGTGCTATTAAAAT	AATCTTTAATATTTCCAAGTAGCCTATACCGTCCTTC
ATTTACAATACAAATTGTGCTATTAAAAT	ATATAATTTTTCCGTTTCCCAACAAGTTTTAATTAA
ATTTACAATACAAATTGTGCTATTAAAAT	TAACACAGAAAAAGTTATTAAATTAAGTTATCAAAG
ATTTACAATACAAATTGTGCTATTAAAAT	GAATTTGTAAGTGAAGTTATGAAAAAAGATAAGGAT
ATTTACAATACAAATTGTGCTATTAAAAT	GAATTTGTAAGTGAAGTTATGAAAAAAGATAAGGAT
ATTTACAATACAAATTGTGCTATTAAAAT	TTTAATGTAGATGAAATAAATCCTATTGTAATGAAAT
ATTTACAATACAAATTGTGCTATTAAAAT	TCAACAATATGCAGATAGAATTGAATTTTTTGACGAG
ATTTACAATACAAATTGTGCTATTAAAAT	GATGGTGTATTGGAAAATAAAACAAGCAAGGAAAAA
ATTTACAATACAAATTGTGCTATTAAAAT	AGAAACTTTATATCAAGCACAGTGGCAAGAATATAA
ATTTACAATACAAATTGTGCTATTAAAAT	TGTTGAAAGTTTTGGATCAGGATATTATTACGAAAA
ATTTACAATACAAATTGTGCTATTAAAAT	TTAAAAGATTGCGTTATATCGAGTTATATTGATACGA
ATTTACAATACAAATTGTGCTATTAAAAT	CAAGATTCGGAAAAGATTTTGCTGGGAGCATTTTCTAC
ATTTACAATACAAATTGTGCTATTAAAAT	ATTAACTTAATTAATGTATTTACAAAATCTTTACTA
ATTTACAATACAAATTGTGCTATTAAAAT	AAGAAGAAACAGAAGCGATTAATATGTCAAGAGAAA
ATTTACAATACAAATTGTGCTATTAAAAT	TATTTGTACCTACTGTTCCTTTTGCTTGTTTTTTA
ATTTACAATACAAATTGTGCTATTAAAAT	ATGACACCGCTCAAAGAAATATACGAAGATGTAAAA
ATTTACAATACAAATTGTGCTATTAAAAT	GTTTATTATAGATTTCTAGCCCCATTATAAAGGCTT
ATTTACAATACAAATTGTGCTATTAAAAT	AGATTTTTCTTTAGACGTGGCTTTTGGACTGGATTT
ATTTACAATACAAATTGTGCTATTAAAAT	GGAGTTGGAACGAAATAACAACTTCTTTGCAAAGCG
ATTTACAATACAAATTGTGCTATTAAAAT	CTCCAAGCGAAGTATTTTTAGTAATTCCGAAAGACG
ATTTACAATACAAATTGTGCTATTAAAAT	CGAAAAGATGTTTATTTTTTTCAGAAAAATTATAAA
ATTTACAATACAAATTGTGCTATTAAAAT	TGTATAATTGCGTATCCGAAATTCCCACAGACTTTG
ATTTACAATACAAATTGTGCTATTAAAAT	CATAACAATATTTCCTTTCTAAATTATATATTCTCA
ATTTACAATACAAATTGTGCTATTAAAAT

>NZ_AP019831|1|1|1140781-1142569|PILER-CR
ATTTACAATACAAATTGTGCTATTAAAAT	CTTTGCAATATCTCCAACTTATATTACAGAGCCAC
ATTTACAATACAAATTGTGCTATTAAAAT	AAAGGGAATATCAAACTTTATCGGCGAACAGCTTAA
ATTTACAATACAAATTGTGCTATTAAAAT	AGTTTGAATACATTGATACTTATGTTAAATTGAAAG
ATTTACAATACAAATTGTGCTATTAAAAT	CATCATCATCATTTAACTTGATTGCACGTTTTCCAGC
ATTTACAATACAAATTGTGCTATTAAAAT	AATCTTTAATATTTCCAAGTAGCCTATACCGTCCTTC
ATTTACAATACAAATTGTGCTATTAAAAT	ATATAATTTTTCCGTTTCCCAACAAGTTTTAATTAA
ATTTACAATACAAATTGTGCTATTAAAAT	TAACACAGAAAAAGTTATTAAATTAAGTTATCAAAG
ATTTACAATACAAATTGTGCTATTAAAAT	GAATTTGTAAGTGAAGTTATGAAAAAAGATAAGGAT
ATTTACAATACAAATTGTGCTATTAAAAT	GAATTTGTAAGTGAAGTTATGAAAAAAGATAAGGAT
ATTTACAATACAAATTGTGCTATTAAAAT	TTTAATGTAGATGAAATAAATCCTATTGTAATGAAAT
ATTTACAATACAAATTGTGCTATTAAAAT	TCAACAATATGCAGATAGAATTGAATTTTTTGACGAG
ATTTACAATACAAATTGTGCTATTAAAAT	GATGGTGTATTGGAAAATAAAACAAGCAAGGAAAAA
ATTTACAATACAAATTGTGCTATTAAAAT	AGAAACTTTATATCAAGCACAGTGGCAAGAATATAA
ATTTACAATACAAATTGTGCTATTAAAAT	TGTTGAAAGTTTTGGATCAGGATATTATTACGAAAA
ATTTACAATACAAATTGTGCTATTAAAAT	TTAAAAGATTGCGTTATATCGAGTTATATTGATACGA
ATTTACAATACAAATTGTGCTATTAAAAT	CAAGATTCGGAAAAGATTTTGCTGGGAGCATTTTCTAC
ATTTACAATACAAATTGTGCTATTAAAAT	ATTAACTTAATTAATGTATTTACAAAATCTTTACTA
ATTTACAATACAAATTGTGCTATTAAAAT	AAGAAGAAACAGAAGCGATTAATATGTCAAGAGAAA
ATTTACAATACAAATTGTGCTATTAAAAT	TATTTGTACCTACTGTTCCTTTTGCTTGTTTTTTA
ATTTACAATACAAATTGTGCTATTAAAAT	ATGACACCGCTCAAAGAAATATACGAAGATGTAAAA
ATTTACAATACAAATTGTGCTATTAAAAT	GTTTATTATAGATTTCTAGCCCCATTATAAAGGCTT
ATTTACAATACAAATTGTGCTATTAAAAT	AGATTTTTCTTTAGACGTGGCTTTTGGACTGGATTT
ATTTACAATACAAATTGTGCTATTAAAAT	GGAGTTGGAACGAAATAACAACTTCTTTGCAAAGCG
ATTTACAATACAAATTGTGCTATTAAAAT	CTCCAAGCGAAGTATTTTTAGTAATTCCGAAAGACG
ATTTACAATACAAATTGTGCTATTAAAAT	CGAAAAGATGTTTATTTTTTTCAGAAAAATTATAAA
ATTTACAATACAAATTGTGCTATTAAAAT	TGTATAATTGCGTATCCGAAATTCCCACAGACTTTG
ATTTACAATACAAATTGTGCTATTAAAAT	CATAACAATATTTCCTTTCTAAATTATATATTCTCA
ATTTACAATACAAATTGTGCTATTAAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019831.1\|WP_155282661.1\|1149598_1150087_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NZ_AP019831.1\|WP_026749133.1\|1151117_1151396_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NZ_AP019831.1\|WP_084533633.1\|1127353_1128895_-\|4-alpha-glucanotransferase	unknown	unknown	gnl\|CDD\|237738
NZ_AP019831.1\|WP_155282662.1\|1154878_1155859_+\|3-phosphoglycerate-dehydrogenase	unknown	unknown	gnl\|CDD\|240639
NZ_AP019831.1\|WP_146996452.1\|1154046_1154775_+\|HAD-IB-family-hydrolase	unknown	unknown	gnl\|CDD\|273654
NZ_AP019831.1\|WP_026749134.1\|1150123_1151116_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|187853
NZ_AP019831.1\|WP_026749140.1\|1142904_1143687_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam01881_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
NZ_AP019831.1\|WP_026749146.1\|1131480_1132695_+\|saccharopine-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|224662
NZ_AP019831.1\|WP_026749143.1\|1135601_1137146_-\|flotillin-family-protein	unknown	unknown	gnl\|CDD\|225177
NZ_AP019831.1\|WP_026749142.1\|1137335_1139996_-\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
NZ_AP019831.1\|WP_026749136.1\|1147180_1149580_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|273707
NZ_AP019831.1\|WP_026749138.1\|1145483_1146380_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|274215
NZ_AP019831.1\|WP_026749141.1\|1140054_1140459_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_026749139.1\|1143711_1145481_+\|CRISPR-associated-protein-Cst1	cas8b2	cd09665_cas8b2_CAS-I-B	gnl\|CDD\|187884
NZ_AP019831.1\|WP_026749148.1\|1129846_1130626_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_026749137.1\|1146382_1147147_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|273860
NZ_AP019831.1\|WP_026749145.1\|1132991_1134032_+\|BMP-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380577
NZ_AP019831.1\|WP_026749149.1\|1129073_1129835_-\|YARHG-domain-containing-protein	unknown	unknown	gnl\|CDD\|372555
NZ_AP019831.1\|WP_026749147.1\|1130654_1130924_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_026749144.1\|1134182_1135487_+\|thymidine-phosphorylase	unknown	unknown	gnl\|CDD\|274244

Protein	Function_ID	Function_description	E-value
NZ_AP019831.1\|WP_155282661.1\|1149598_1150087_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	5.38033e-56
NZ_AP019831.1\|WP_026749133.1\|1151117_1151396_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.72593e-26
NZ_AP019831.1\|WP_084533633.1\|1127353_1128895_-\|4-alpha-glucanotransferase	gnl\|CDD\|237738	PRK14508, PRK14508, 4-alpha-glucanotransferase; Provisional.	0
NZ_AP019831.1\|WP_155282662.1\|1154878_1155859_+\|3-phosphoglycerate-dehydrogenase	gnl\|CDD\|240639	cd12162, 2-Hacid_dh_4, Putative D-isomer specific 2-hydroxyacid dehydrogenases. 2-Hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	2.59976e-119
NZ_AP019831.1\|WP_026749134.1\|1150123_1151116_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	9.95708e-161
NZ_AP019831.1\|WP_026749140.1\|1142904_1143687_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	6.56509e-16
NZ_AP019831.1\|WP_026749146.1\|1131480_1132695_+\|saccharopine-dehydrogenase-family-protein	gnl\|CDD\|224662	COG1748, LYS9, Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism].	1.45951e-167
NZ_AP019831.1\|WP_026749143.1\|1135601_1137146_-\|flotillin-family-protein	gnl\|CDD\|225177	COG2268, COG2268, Uncharacterized protein conserved in bacteria [Function unknown].	1.98525e-43
NZ_AP019831.1\|WP_026749142.1\|1137335_1139996_-\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NZ_AP019831.1\|WP_146996452.1\|1154046_1154775_+\|HAD-IB-family-hydrolase	gnl\|CDD\|273654	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490. This hypothetical equivalog is a member of the IB subfamily (TIGR01488) of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. The sequences modelled here are all bacterial. The IB subfamily includes the enzyme phosphoserine phosphatase (TIGR00338). Due to this relationship, several of these sequences have been annotated as "phosphoserine phosphatase related proteins," or "Phosphoserine phosphatase-family enzymes." There is presently no evidence that any of the enzymes in this model possess PSPase activity. OMNI\|NTL01ML1250 is annotated as a "possible transferase," however this is due to the C-terminal domain found on this sequence which is homologous to a group of glycerol-phosphate acyltransferases (between trusted and noise to TIGR00530). A subset of these sequences including OMNI\|CC1962, the Caulobacter crescentus CicA protein cluster together and may represent a separate equivalog. [Unknown function, Enzymes of unknown specificity].	3.60779e-52
NZ_AP019831.1\|WP_026749138.1\|1145483_1146380_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|274215	TIGR02585, conserved_protein, CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This clade is a member of the DevR family (TIGR01875) and includes the DevR protein of Myxococcus xanthus, a protein whose expression appears to be regulated through a number of means, including both location and autorepression; DevR mutants are incapable of fruiting body development.	8.29478e-56
NZ_AP019831.1\|WP_026749139.1\|1143711_1145481_+\|CRISPR-associated-protein-Cst1	gnl\|CDD\|187884	cd09754, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as CXXC_CXXC family.	8.79429e-14
NZ_AP019831.1\|WP_026749136.1\|1147180_1149580_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	2.63837e-58
NZ_AP019831.1\|WP_026749144.1\|1134182_1135487_+\|thymidine-phosphorylase	gnl\|CDD\|274244	TIGR02644, Thymidine_phosphorylase, pyrimidine-nucleoside phosphorylase. In general, members of this protein family are designated pyrimidine-nucleoside phosphorylase, enzyme family EC 2.4.2.2, as in Bacillus subtilis, and more narrowly as the enzyme family EC 2.4.2.4, thymidine phosphorylase (alternate name: pyrimidine phosphorylase), as in Escherichia coli. The set of proteins encompassed by this model is designated subfamily rather than equivalog for this reason; the protein name from this model should be used when TIGR02643 does not score above trusted cutoff. [Purines, pyrimidines, nucleosides, and nucleotides, Other].	0
NZ_AP019831.1\|WP_026749145.1\|1132991_1134032_+\|BMP-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380577	cd06354, PBP1_PrnA-like, periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea. Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea. The PnrA lipoprotein, also known as Tp0319 or TmpC, represents a novel family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC) transport system (pnrABCDE). It shows a striking structural similarity to another basic membrane lipoprotein Med which regulates the competence transcription factor gene, comK, in Bacillus subtilis. The members of PnrA-like subgroup are likely to have similar nucleoside-binding functions and a similar type 1 periplasmic sugar-binding protein-like fold.	7.19096e-111
NZ_AP019831.1\|WP_026749149.1\|1129073_1129835_-\|YARHG-domain-containing-protein	gnl\|CDD\|372555	pfam13308, YARHG, YARHG domain. This presumed extracellular domain is about 70 amino acids in length. It is named YARHG after a conserved motif in the sequence. This domain is associated with peptidases and bacterial kinase proteins. Its molecular function is unknown.	2.34307e-15
NZ_AP019831.1\|WP_026749137.1\|1146382_1147147_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|273860	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family is represented by TM1800 from Thermotoga maritima. It is related to TIGR01868 (CRISPR-associated protein, CT1976 family).	1.77673e-19

>NZ_AP019831.1|WP_026749141.1|1140054_1140459_-|hypothetical-protein
MRKIVIDKRKSVMLVMTCILFMMTYSSLLGTPSFSRKLSVFVDENNLSHEDIRDLIVKINQIESVNNRRLTQELKKIGKRKEKEKGKQKNSLFLLFEKNQNTVFYKNSDKIPKNIGNISAFLMKKDENNLRTRE
>NZ_AP019831.1|WP_026749142.1|1137335_1139996_-|preprotein-translocase-subunit-SecA
MLKKIGEKIFGTSDEREIKKMQKLVDKINEVEPLFEKMTDEQLSHKTVEFKERLQKETLDDILVEAFATVREASKRLMGMRHYDVQLIGGMILHKGCIAEMKTGEGKTLMATLPIYLNALPGKGVHVVTVNDYLAKRDRDIMAGLFEFLGLTSGVVVGNITPDQRKTAYNCDITYGTNNEFGFDYLRDNMVGELDEKVQRGHNYVIVDEVDSILIDEARTPLIISGAAEETTEWYNTFSEVAKRLKRSYKTEEIKDKKNTVIPDEDWEDYEVDEKSHTVTITDKGIKNVERMLKIDNLYSPEYVELTHFLTQALKAKELFKLDRDYIINDDNEVIIVDEFTGRLMEGRRYSDGLHQAIEAKEKLEVAGENQTLATITLQNYFRMYEKLSGMTGTAKTEEDEFKQIYSLKVIVVPTNKPVARVDLPDVIYMNKKAKYKAIARKIEELYHKGQPVLVGTASIQHSEEVSALLKKAKIPHEILNAKHHEREAEIIAQAGRFKTVTIATNMAGRGTDIKLGGDAESFATKVAVKGTPEYEDVHSAYVKECEEDKKKVLAAGGLFILGTERHESRRIDNQLRGRAGRQGDPGTSEFYLSLDDDLMRLFGGDRLKSMMKMLKIDEDEEIRHKQISKSVENAQKRIESRNFSSRKSLIEYDDVNNTQREVVYEQRDAILKNENLKELIINMISDTVDDIVNSAYVGEGNGEKDFNLLSDKLHETFEYEISEELQNASADEISNKVYDDLVRIYDEKEEAIGEEIFRRIERYIMLEVLDSKWRQHLKDLTELREGIRLRSYGQRNPIHDYKIVGYDIYNEMIDAIKRETSSFILKLRVRGEEDTNNLTHEEVSNVRYEHEENEMMGDDVSARTPNEPHRPLSRRERRERERRNV
>NZ_AP019831.1|WP_026749143.1|1135601_1137146_-|flotillin-family-protein
MGFLSNNFVPILIVLIIIFILSLVGFIRVPMDRAAFISGFKRRVVTGKLAFYLRYFERVDYLDLSLFSVDVNTSVFVPTNDFINIKADAIVKLQIAQEPEILNIASKNFLNKKSEYIGESVKEVLEGNLREIIGQMNLKDMVQNRKEFNVKVQENVSPDLREMGLVVVSFAVQSFMDEKGVIDNLGIENISKISKDASIAKAQAEKEIAIAKANADKEAKDIELKVAEEIAEKTNKLEIKKADLKIESDTKKASADMTYQLETERKRKELEEVQGESNFTRETQAIKTNQAKLEAEIKVDNQIKSDAELYRKTKQAESKLIEEQREAEAILYQKTKEAEALKIMAQQEGEALKIKAQADSESIKLKAQAEAESIKLKALAEAQSKREIGLAEAEAIKAKALAEAEGIDKKADAMKKYGNAAIMEMYFKALPEISKNVAAPLNNIDKITMYGDGNTSKLVGDITKSIAQINDGITDSTGIDLKSVLAGMLGGKIISDKERLDSETKNDVVAKKNK
>NZ_AP019831.1|WP_026749144.1|1134182_1135487_+|thymidine-phosphorylase
MRIVDIIQKKRDNEKLSDKELEFLLNEYLAGNVPDYQMSAFLMAVYFNDMTQEELLKFTMLMRDSGDVIKFDEINRFLVDKHSTGGVGDKVTAVLSPILSALGMGNVKLSGKGLGHTGGTIDKFESIKGFKFSTTKEELIKIANKTGIGLMGYSDNIVPLDKKLYSLRDVTATVPSIPLIASSIMSKKLAIHSDVIILDVKVGDGAFMKDLGQAKKLAERMIEIGKGAGKKVKVVLSNMDEPLGHSIGNANEIIEAIEFLKGNCVDDLKEVVYTIVSLALKEKGEVRDFNEAKSKIDEVINNGSALKILGEFIEASGGNKELVNNYDLLPKAKSVMEVFSENDGYVKKIKTEEIGKAAMIIGAGRAKKEDEVDHAVGINIFRKVGEKVGKNEKIAEIYYNNDKNVQESRNMILDAFVLTKEEVEKPKAILEIIE
>NZ_AP019831.1|WP_026749145.1|1132991_1134032_+|BMP-family-ABC-transporter-substrate-binding-protein
MKKILTIFSVIFALMLVVACGNKPATGEQVKDGKTSADSTNSKKAVAVVYSTGGKGDKSFNDATFRGLERAQKELGISFKEYEPKDPSTEAKNALTQFAESGEFELIIAVGYSMKDSLVAVAQAFPDQKFAIIDETVDGLPNVASILFKEHEGSFLVGALAGMMDKTGTVGFVGANESELINRFYAGYAQGARYVKPDIKVISVYIGGSNSFNDQASAKAKTETLIQQGADVIYHAAGASGLGVFQAVKEKNVYGIGVDSNQDNLYPGIILTSMMKYVDNAVFDIVKSTADGKFEAKLQTFGIKENGVGTTDFEFTKDKIGEENIKRLEQIKQDIKDGKIQVKSAL
>NZ_AP019831.1|WP_026749146.1|1131480_1132695_+|saccharopine-dehydrogenase-family-protein
MGKKALVIGAGGVSNVVCHKCAQNSEVFSSIMIASRRKVKCDEIRERIEKSKYAGRIEIQTAQVDANNVPELVALINEYKPDIVINVALPYQDLTIMDACLETKTDYLDTANYEPLDTAKFEYKWQWAYKEKFEKAGITAILGSGFDPGVTGVFSAYAQKHYFDEINYIDILDANAGDHGYPFATNFNPEINIREVTANGSYWEDGKWVETEPMEIKRVYNFPQIGEKDMYLLHHEELESLALNIKGIKRIRFFMTFGQSYLTHLKVLENVGMTSIEPIEFEGKQIVPLQFLTAVLPDPASLGPRTKGKTNIGNIFRGKKDGVEKTYYVYNVCDHQECYKEVSSQAISYTTGVPAMIGAAMVLTGEWKKPGVFNVEEMNPDPFMDALNKFGLPWVEDFNPTLVD
>NZ_AP019831.1|WP_026749147.1|1130654_1130924_-|hypothetical-protein
MTKKILIAIIALIVGIGAGLLYSRYQRYLSKSQVHTITYPTSEEDCDKTINSYRQQIMRAYDSEDEAEYKRLNDEAEKITNHCLNLMSN
>NZ_AP019831.1|WP_026749148.1|1129846_1130626_-|hypothetical-protein
MQEKEIFRFEKSGMKSKGAWTFVGFGTIALFGGGIYSFIGILMLAYGIYLLTKKSKVIVYTTGFVISEGKDLKNISFDRVLGIKGELGQKVKILYLKKPFSAYNENELNNISNNLNTLSESIIFDDELLEKDFINVFNIIKEQFKNYVFEHYNNDLEKIITSPYLFEQISNDKLNFTRTKFWGGLADEIIQLQYGDAINVTTRKKAYVTNGRGDIRQAGQSFEPQWQFASTSTKCDTINLINATIIQETLSKKYNIKFI
>NZ_AP019831.1|WP_026749149.1|1129073_1129835_-|YARHG-domain-containing-protein
MKTIFFIFTVLLILTGCGTQSETQNEKKSLGLSENELSEYTNRLRNFLKTNKDQVNQQDLLNEDGTPKITCSQKDVLLEALLTSPDAVTNGNSIPLIAGMLYAQQLKIINEAACYNSDGTITAPKKETDTTEQATSNPSEYENQNTSENSTSISSTNKNTNDLDLEDLNNLKHEVMDNGNESAFNKYSKYQLKILRNMMFAERGFAFKKGGEMRTYFENKSWYSPTIEDQSEIQLNDYDKEFVLKLKKYEGID
>NZ_AP019831.1|WP_084533633.1|1127353_1128895_-|4-alpha-glucanotransferase
MRNKKFDFINNFKEDIEMFERSSGILLHPTSLPGKYGIGSLGKEAYKFVDFLKKANQKLWQIFPLGPTGYGDSPYQCFSTFAGNPYLIDFDLLIEQNLLTEEDLKDVDFGGNEESVDYGAIYNQKYPLLRKAYENFKTNGNDDLKGKLDAFKAENSDWLNDYSLFISLKNHFNGLPWTEWPHDIKVREEAAVNKYREELADEIEYNNFIQCLFFDQWNNVKKYANDNGIKVIGDIPIFVAVDSSDAWANPEIFLFDPELKPVKVAGVPPDYFSATGQLWGNPLYDWNKLKELNYKWWVDRVRANLSTCDIIRIDHFRGFDEYWAVPFGDDTAVNGQWVKGPGIDLFNKIKEELGSLPIIAEDLGFMTQGVIDLRESTGFPGMKILGFAFDSNEENEYLPHTYTKNCVVYTGTHDNDTLMGWFTKAKEEDRQFARDYLHSQSDDEIYWDALRGAWGSVANMAIAPIQDFLGLGSEARINTPGIASGNWQWRLKDGVLTDELAERIAKLTKVYSR
>NZ_AP019831.1|WP_026749140.1|1142904_1143687_+|CRISPR-associated-endoribonuclease-Cas6
MRFKINIELTEGNSFPINWRSKILCVLKTGLKKCDNEIFEEFFGSAKQKNYTWSAYFQNVKFEKDKVKFLGEEKKIIVNLSAYDNVDSLNIYNAFSGIRFKEIKISEETKVVVTNISILPRQIIKDNILIVKTMSPIVCRDHDQETKKDTYYIGTDDKFSKIIKRNLYLKLKELKGEYVKKDIEDLIIDSSQTKKVVVKHYDKTKKDKTLNYENKFNGKFLDTSVGILKLEGKSYILDYIYNAGIGSITGSGFGMLEKLK
>NZ_AP019831.1|WP_026749139.1|1143711_1145481_+|CRISPR-associated-protein-Cst1
MSNEKIELKLKDWLFNAGLLGFINILGEEAKSSGELEIDNKNRLIKFSPKVLENFEYKYFDFFIKRYGKTLTYGKILEFEKYIDEFEENGEKIKSINELKMINDKITFFKAKIKSESYKKAYDFIEKNGTNKILGLEKELKKIKEPKENIAEISNDDIKNNLKIMKEIIDFFKKKITDKEGNVKNYLAAKNIAYVIINNAWSSVSFLNKANAAKDIYEEYKSYFVEPALEYVNADKSKFKYKCVISNMQMKNYKNTLGFLNDTGFDVSRKPSHVWNFVNDIAVTPLVTLIYSCVPAGFIYGADKGIFVNANHNIDQLCNINNGIAYNILEDESEEKNINLYKNLLKEIKKEKDNTKYELSDIQIVKFEEGHYKFTLLSRNILKLLSENKEKLDDLLDKWYLIDKRYFNLYDTTITELLNNQNLFSLINKLCYYKISKAKLSCKLKNIEDLLKINLDYIRRLKKMDKQEIIEKKENKKTSEELTEKDVFYIRRDAMIFREEYIRKSGNDKKIGSLLYRLQNALRINNVDMFMDALISAHAYAGKNISSLFAKALLNDENFQTLGHGFLLGLLGEDKSKNENKTDKKEGNE
>NZ_AP019831.1|WP_026749138.1|1145483_1146380_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MKKKGLTFTAIFLAQSANYGEGIGNVAALKKLSRNKGEQYTYISRQAIRYNIIEQLGEEKSPVKAEGSGDKKVVQFSADTTIKDYSELDFFGYMKTIKGENSKNRSAIVRLSNAISLETFKGDLEFLTNKGLADRIGEFPNIAQAEIHKSYYKYTVTIDLDRIGIDELDKIEVSNEEKSRRVRKLLDTISLLYRDIKGRREDLKPLFIIGGVYDIKNPFFENIVDVKNNKILADKLCSGIYDYIEKDTISGIVKEQFENDTEVEEKLKGKNINVLNVPEFFKQLKEKVDNYYTEKVDG
>NZ_AP019831.1|WP_026749137.1|1146382_1147147_+|type-I-B-CRISPR-associated-protein-Cas5
MKAVKLKLYQNMVNYKVPTSFQLKESYPLPPYSTVIGMIHSLCDFKEYKPMKISISGNYFSKVNDLYTRYEFKNGNPFEMGRHQLNVNGYGINRGVATAELLVDVNLTIHIIPEDQSEEFLDIIFEAFKYPREYPSLGRREDIVLIKDVKIVDVEKKKLEKDLSNGEDDFAYIPVNFIQEKLVNYGDKKNGMNIYGTRYELTKNYILNNIGTKSKSKMIRSWEKEEVIYSSNIKGFKRREVPVDTDNEIVFCEL
>NZ_AP019831.1|WP_026749136.1|1147180_1149580_+|CRISPR-associated-helicase/endonuclease-Cas3
MKNNFLAKSSGETILRHTENLFNNFMKIFMIYPKLNVEKRLLLLACIYHDLGKINQKFQSKLSGEKQSGEIPHGILSTSFINDDILIEYHHFSEDEIKILAHSVALHHERNLMEINDSDLSDEIYSMNNEVKNFSKELKILENIYFEYFKNTENYKDRKAIFNWEDGKVELAELSSLFYEIGSRVYSDVEGSETFQKYVMLKGLLNKIDYAASSYIPVEEKNDFLEEKMNAFLKNVLKKDNPENDWNELQKFMIHNRNKNVVVVAQTGYGKTEAGLLWIGNNKGFFTLPLRVAINAIFDRVKNQIVIEKLENRIGLLHSDFREIYIEDIKKKEKNNLEKMDNDELFMYMDKTKQLSLPLTVCTIDQLFDFVFRAPGFELKVATLSYSKVVIDEIQMYSTDLLAYLIYGLKYITDFGGKFAIMTATLPGIITDLLKKEEIEFVTTEPFINDKKRHNLKVLKEVINAKFIKENYKYNKILVVCNTVKKSKQIYEELKNLGIECKELNLLHSRFIKKDRAEKEKEISEFANPKRFKESVKKERKSKNIFENGIWIGTQVVEASLDLDFDILITELSDLNGLFQRMGRCYRNREILDEKYNCYVFTEECSGIKSSKAVIDKEIHQKSKEALINIDGLLTEKEKLELIDEVYSTESLKDTEYYGKLVKNIYALKNYIVEYEKTKSEVQKIFRNIASRDIIPKIIYQENEKEIKKNIEILQKKAKGLDEEKRKNLRSEKIEARREINQFKVAIPEYEFDDISPEQVEKIEINDYETLIILDCDYSYEKGFEVKMKNQDFFEDNTF
>NZ_AP019831.1|WP_155282661.1|1149598_1150087_+|CRISPR-associated-protein-Cas4
MKITGLMINYYFVCKRKLWCQSKNINLEEENENVQLGKLIDENSYNLETKQVMIEETVNIDFIRKWQVVHEVKKSKAVEEAAIWQVKYYIYFLKRRGIKIEKGIIDYPVIRERKEIILTEEDENTLKEILTDIEKICQNEKAPPVINNKIYKKCAYYEFCYV
>NZ_AP019831.1|WP_026749134.1|1150123_1151116_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MAESYFIFSNGELKRKDNVVRITAPDGRFKDIKIEVTRDIYLFGEVSLNTKCLNYLAQNKIPVHIFNYYGFYTGTFYPKESNVSGKLFVKQVENYTDNSKRIELAQLIIDAASTNILRNLRYYQERGKDLESVITEIKALKKGIFRTNEINELMGIEGSIRRTYYTAWNTIVNQEIDFEKRVKRPPDNMINTMISFLNTLVYTACLSEIYVSQLNPTISYLHSVGERRFSLSLDIAEVFKPLLADRIIFSLLNKKMITEKDFVKDSNYFYMKENAQKLILKTFNERLETSIKHRDLNRKVSYRHLMRLEAYKLVKHLLEDKKYEGFKIWW
>NZ_AP019831.1|WP_026749133.1|1151117_1151396_+|CRISPR-associated-endonuclease-Cas2
MYIILVYDILTDDNGPRISRNVFKICKKYLTNVQKSVFEGEITPVLLKKLNLELKRYIRKDKDSLIIFKSRQEKWLEKEFWGLEDDKTSNFF
>NZ_AP019831.1|WP_146996452.1|1154046_1154775_+|HAD-IB-family-hydrolase
MKKNVAAFFDIDGTIYRDSLLIEHFKMLVQYEYIDMMTWEGKVKEKFSKWENRTGDYDDYLDELVQTYMEALKNFSKEDMDFIAKRVMKLKGDKVYRYTRERLKYHKEKNHKVIIISGSPDFLVSKMAERYGVKDYRASTYEVNENGIFTGKVIPMWDAKSKQKAIADFCKMYEIDLTKSYAYGDTTGDLTMFKNVGNAIAINPAKKLLQKIKRDKELKEKVMIVVERKDVIYKLKADVDII
>NZ_AP019831.1|WP_155282662.1|1154878_1155859_+|3-phosphoglycerate-dehydrogenase
MDKNLKIVYLDRITAGPIDLKERFSKYGEYIEYEDTDSGEVDERIKDVDIVITTRIKLGREQFKKAKKLKLILITATGFNHIDVKSANEFGIKVANVSGYSTNSVAQLAITFLLNELTPVNRYYEEVKDGKWMDITVPDYQKYPIDDANGKILGIVGFGNIGKRVAQVAEILGMEVMVAKNTEKDNAKTDSVIEKGGFLRYDLYEVLEKCDVLTLHVPLTDSTRNLINLEKMKKMKKSAIILNLARGPVINQEDLYFALKNKIIKSAAIDVTSVEPIEKNSKLFELDNILVTPHIAWKSEKSMVKLMDDVEENLKLFLEGKLEGLK

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Crispr_ID: NZ_AP019831_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019831_2

1151601-1153889

Unclear

Consensus_repeat	Method
ATTTACAATACAAATTGTGCTATTAAAAT	PILER-CR
ATTTTAATAGCACAATTTGTATTGTAAAT	CRISPRCasFinder
ATTTTAATAGCACAATTTGTATTNNGTAAAT	CRT

35 spacers

cas2,cas1,cas4,cas3,cas5,cas7,cas8b2,cas6

The CRISPR arrays of NZ_AP019831_2

>merge|NZ_AP019831|2|1151601-1153889|PILER-CR,CRISPRCasFinder,CRT
ATTTTAATAGCACAATTTGTATTGTAAATTCCAATTAGGGTGGTTAGATTATAACATAGAATATTATTTTAATAGCACAATTTGTATTGTAAATTTGAAAGAGGCTAATGCGGCAGTTATAAGAATCAATATTTTAATAGCACAATTTGTATTGTAAATATTACTTGAGTTAGGAATTGAGCATAAGGACAAATAATTTTAATAGCACAATTTGTATTGTAAATGTTTTCGTTAGAGTTTTCAGGGACTTCATTTCTTCCATTTTAATAGCACAATTTGTATTGTAAATGTACACCATTCATAACGAATAGGCATTTTTCATCAGCATTTTAATAGCACAATTTGTATTGTAAATATGGAAACAGTTTATGCAATGCTTGGTAAAATGAATATTTTAATAGCACAATTTGTATTGTAAATGATGATGTTTAGAACACAAGCTCATAAATGGTGTTTATTTTAATAGCACAATTTGTATTGTAAATTTTCGTTTCCTAAATCATCAAAAATAACTAAATCAATTTTAATAGCACAATTTGTATTGTAAATCTCTGATTTTCCTATCCATTATCCACCACCTCTCCCATTTTAATAGCACAATTTGTATTGTAAATTTATATATGCTAGAGTCAGCACAGAAATGCAGGAAGATTTTAATAGCACAATTTGTATTGTAAATCTATTTTACTTTTAACGGTTTAAAAGCATTTGGTCTATTTTAATAGCACAATTTGTATTGTAAATTCAAATATATTGAATACGGACCAGTTCATTAATTATATTTTAATAGCACAATTTGTATTGTAAATTAAAAATTTATAAATAAATTTAAATCATATTTATTAATTTTAATAGCACAATTTGTATTGTAAATTTTTTATCGCTAAATACTATTTTTATACAATTTTCTATTTTAATAGCACAATTTGTATTGTAAATGAACATTGATAGAGAAATAAAATAACTCTTTACAAATATTTTAATAGCACAATTTGTATTGTAAATTGCTACTGTTAAAATTGAACTAATAGGAGGATTGAAATTTTAATAGCACAATTTGTATTGTAAATTAAAAACAAGGCTTTAGAATACGGGGGAGTAGATAAATTTTAATAGCACAATTTGTATTGTAAATCTCCTAAATAATCTTTTTGTTTATTGTTTGCAGGTTATTTTAATAGCACAATTTGTATTGTAAATTTTGATTTAGATAAAAGGTTGCAGACAATTGTAATCATTTTAATAGCACAATTTGTATTGTAAATAATCTTCTGCTAATGATTGAAACAGGAACATTTTTTATTTTAATAGCACAATTTGTATTGTAAATAATCCCCTAATAATAAAGGTTTTGTTGGTCTTACAACATTTTAATAGCACAATTTGTATTGTAAATTTAGGATGTATTTTTGTTATCTCTGCTATTAAAGAAGATTTTAATAGCACAATTTGTATTGTAAATTTTGCTGTGCCAACTTCTGATATAGAACTTTTGAAAATTTTAATAGCACAATTTGTATTGTAAATCATCTTTGAAAAATAAATAACAATATTCTTTATACTATTTTAATAGCACAATTTGTATTGTAAATGTGGATTAATCGTTTTTTGTGGAAAAAAGGAGGGTGATTTTAATAGCACAATTTGTATTGTAAATTTTATTGTGTTTTTCATTTCTACACCTCTTTACTTAATTTTAATAGCACAATTTGTATTGTAAATTTATTCTCATTGAACGTTCCAGGTCCTTCTAAAGTATTTTAATAGCACAATTTGTATTGTAAATGAAAAAATGTGGGAAGAATTGACGGAAAGAGCGGAAATTTTAATAGCACAATTTGTATTGTAAATTTTAATACTCCCTTATTTCATTTTTACCCCCTTTTGAATTTTAATAGCACAATTTGTATTGTAAATATGATTGAAACAGGGCATTTCAAGAACAATATCGCCATTTTAATAGCACAATTTGTATTGTAAATTCGCTACAATGATAAGCGATGTGTCAGATAACGAGAATTTTAATAGCACAATTTGTATTGTAAATAGCTCATAAGTGATTGTGAGTTTGGATAAGATATTAATTTTAATAGCACAATTTGTATTGTAAATAGTTGTAAAATTCCTTTGTAATTCAAAAGAAACATCATTTTAATAGCACAATTTGTATTGTAAATAAACCTTTCAAAAACTCCTGCCTTGCAATTACAGCTATTTTAATAGCACAATTTGTATTGTAAATTACATTTTACCCTTGACTATTGCAAGCATAATTTGTAAATTGTAAAA

>NZ_AP019831|2|2|1151601-1153842|PILER-CR
ATTTTAATAGCACAATTTGTATTGTAAAT	TCCAATTAGGGTGGTTAGATTATAACATAGAATATT
ATTTTAATAGCACAATTTGTATTGTAAAT	TTGAAAGAGGCTAATGCGGCAGTTATAAGAATCAAT
ATTTTAATAGCACAATTTGTATTGTAAAT	ATTACTTGAGTTAGGAATTGAGCATAAGGACAAATA
ATTTTAATAGCACAATTTGTATTGTAAAT	GTTTTCGTTAGAGTTTTCAGGGACTTCATTTCTTCC
ATTTTAATAGCACAATTTGTATTGTAAAT	GTACACCATTCATAACGAATAGGCATTTTTCATCAGC
ATTTTAATAGCACAATTTGTATTGTAAAT	ATGGAAACAGTTTATGCAATGCTTGGTAAAATGAAT
ATTTTAATAGCACAATTTGTATTGTAAAT	GATGATGTTTAGAACACAAGCTCATAAATGGTGTTT
ATTTTAATAGCACAATTTGTATTGTAAAT	TTTCGTTTCCTAAATCATCAAAAATAACTAAATCA
ATTTTAATAGCACAATTTGTATTGTAAAT	CTCTGATTTTCCTATCCATTATCCACCACCTCTCCC
ATTTTAATAGCACAATTTGTATTGTAAAT	TTATATATGCTAGAGTCAGCACAGAAATGCAGGAAG
ATTTTAATAGCACAATTTGTATTGTAAAT	CTATTTTACTTTTAACGGTTTAAAAGCATTTGGTCT
ATTTTAATAGCACAATTTGTATTGTAAAT	TCAAATATATTGAATACGGACCAGTTCATTAATTAT
ATTTTAATAGCACAATTTGTATTGTAAAT	TAAAAATTTATAAATAAATTTAAATCATATTTATTA
ATTTTAATAGCACAATTTGTATTGTAAAT	TTTTTATCGCTAAATACTATTTTTATACAATTTTCT
ATTTTAATAGCACAATTTGTATTGTAAAT	GAACATTGATAGAGAAATAAAATAACTCTTTACAAAT
ATTTTAATAGCACAATTTGTATTGTAAAT	TGCTACTGTTAAAATTGAACTAATAGGAGGATTGAA
ATTTTAATAGCACAATTTGTATTGTAAAT	TAAAAACAAGGCTTTAGAATACGGGGGAGTAGATAA
ATTTTAATAGCACAATTTGTATTGTAAAT	CTCCTAAATAATCTTTTTGTTTATTGTTTGCAGGTT
ATTTTAATAGCACAATTTGTATTGTAAAT	TTTGATTTAGATAAAAGGTTGCAGACAATTGTAATC
ATTTTAATAGCACAATTTGTATTGTAAAT	AATCTTCTGCTAATGATTGAAACAGGAACATTTTTT
ATTTTAATAGCACAATTTGTATTGTAAAT	AATCCCCTAATAATAAAGGTTTTGTTGGTCTTACAAC
ATTTTAATAGCACAATTTGTATTGTAAAT	TTAGGATGTATTTTTGTTATCTCTGCTATTAAAGAAG
ATTTTAATAGCACAATTTGTATTGTAAAT	TTTGCTGTGCCAACTTCTGATATAGAACTTTTGAAA
ATTTTAATAGCACAATTTGTATTGTAAAT	CATCTTTGAAAAATAAATAACAATATTCTTTATACT
ATTTTAATAGCACAATTTGTATTGTAAAT	GTGGATTAATCGTTTTTTGTGGAAAAAAGGAGGGTG
ATTTTAATAGCACAATTTGTATTGTAAAT	TTTATTGTGTTTTTCATTTCTACACCTCTTTACTTA
ATTTTAATAGCACAATTTGTATTGTAAAT	TTATTCTCATTGAACGTTCCAGGTCCTTCTAAAGT
ATTTTAATAGCACAATTTGTATTGTAAAT	GAAAAAATGTGGGAAGAATTGACGGAAAGAGCGGAA
ATTTTAATAGCACAATTTGTATTGTAAAT	TTTAATACTCCCTTATTTCATTTTTACCCCCTTTTGA
ATTTTAATAGCACAATTTGTATTGTAAAT	ATGATTGAAACAGGGCATTTCAAGAACAATATCGCC
ATTTTAATAGCACAATTTGTATTGTAAAT	TCGCTACAATGATAAGCGATGTGTCAGATAACGAGA
ATTTTAATAGCACAATTTGTATTGTAAAT	AGCTCATAAGTGATTGTGAGTTTGGATAAGATATTA
ATTTTAATAGCACAATTTGTATTGTAAAT	AGTTGTAAAATTCCTTTGTAATTCAAAAGAAACATC
ATTTTAATAGCACAATTTGTATTGTAAAT	AAACCTTTCAAAAACTCCTGCCTTGCAATTACAGCT
ATTTTAATAGCACAATTTGTATTGTAAAT

>NZ_AP019831|2|2|1151601-1153842|CRISPRCasFinder
ATTTTAATAGCACAATTTGTATTGTAAAT	TCCAATTAGGGTGGTTAGATTATAACATAGAATATT
ATTTTAATAGCACAATTTGTATTGTAAAT	TTGAAAGAGGCTAATGCGGCAGTTATAAGAATCAAT
ATTTTAATAGCACAATTTGTATTGTAAAT	ATTACTTGAGTTAGGAATTGAGCATAAGGACAAATA
ATTTTAATAGCACAATTTGTATTGTAAAT	GTTTTCGTTAGAGTTTTCAGGGACTTCATTTCTTCC
ATTTTAATAGCACAATTTGTATTGTAAAT	GTACACCATTCATAACGAATAGGCATTTTTCATCAGC
ATTTTAATAGCACAATTTGTATTGTAAAT	ATGGAAACAGTTTATGCAATGCTTGGTAAAATGAAT
ATTTTAATAGCACAATTTGTATTGTAAAT	GATGATGTTTAGAACACAAGCTCATAAATGGTGTTT
ATTTTAATAGCACAATTTGTATTGTAAAT	TTTCGTTTCCTAAATCATCAAAAATAACTAAATCA
ATTTTAATAGCACAATTTGTATTGTAAAT	CTCTGATTTTCCTATCCATTATCCACCACCTCTCCC
ATTTTAATAGCACAATTTGTATTGTAAAT	TTATATATGCTAGAGTCAGCACAGAAATGCAGGAAG
ATTTTAATAGCACAATTTGTATTGTAAAT	CTATTTTACTTTTAACGGTTTAAAAGCATTTGGTCT
ATTTTAATAGCACAATTTGTATTGTAAAT	TCAAATATATTGAATACGGACCAGTTCATTAATTAT
ATTTTAATAGCACAATTTGTATTGTAAAT	TAAAAATTTATAAATAAATTTAAATCATATTTATTA
ATTTTAATAGCACAATTTGTATTGTAAAT	TTTTTATCGCTAAATACTATTTTTATACAATTTTCT
ATTTTAATAGCACAATTTGTATTGTAAAT	GAACATTGATAGAGAAATAAAATAACTCTTTACAAAT
ATTTTAATAGCACAATTTGTATTGTAAAT	TGCTACTGTTAAAATTGAACTAATAGGAGGATTGAA
ATTTTAATAGCACAATTTGTATTGTAAAT	TAAAAACAAGGCTTTAGAATACGGGGGAGTAGATAA
ATTTTAATAGCACAATTTGTATTGTAAAT	CTCCTAAATAATCTTTTTGTTTATTGTTTGCAGGTT
ATTTTAATAGCACAATTTGTATTGTAAAT	TTTGATTTAGATAAAAGGTTGCAGACAATTGTAATC
ATTTTAATAGCACAATTTGTATTGTAAAT	AATCTTCTGCTAATGATTGAAACAGGAACATTTTTT
ATTTTAATAGCACAATTTGTATTGTAAAT	AATCCCCTAATAATAAAGGTTTTGTTGGTCTTACAAC
ATTTTAATAGCACAATTTGTATTGTAAAT	TTAGGATGTATTTTTGTTATCTCTGCTATTAAAGAAG
ATTTTAATAGCACAATTTGTATTGTAAAT	TTTGCTGTGCCAACTTCTGATATAGAACTTTTGAAA
ATTTTAATAGCACAATTTGTATTGTAAAT	CATCTTTGAAAAATAAATAACAATATTCTTTATACT
ATTTTAATAGCACAATTTGTATTGTAAAT	GTGGATTAATCGTTTTTTGTGGAAAAAAGGAGGGTG
ATTTTAATAGCACAATTTGTATTGTAAAT	TTTATTGTGTTTTTCATTTCTACACCTCTTTACTTA
ATTTTAATAGCACAATTTGTATTGTAAAT	TTATTCTCATTGAACGTTCCAGGTCCTTCTAAAGT
ATTTTAATAGCACAATTTGTATTGTAAAT	GAAAAAATGTGGGAAGAATTGACGGAAAGAGCGGAA
ATTTTAATAGCACAATTTGTATTGTAAAT	TTTAATACTCCCTTATTTCATTTTTACCCCCTTTTGA
ATTTTAATAGCACAATTTGTATTGTAAAT	ATGATTGAAACAGGGCATTTCAAGAACAATATCGCC
ATTTTAATAGCACAATTTGTATTGTAAAT	TCGCTACAATGATAAGCGATGTGTCAGATAACGAGA
ATTTTAATAGCACAATTTGTATTGTAAAT	AGCTCATAAGTGATTGTGAGTTTGGATAAGATATTA
ATTTTAATAGCACAATTTGTATTGTAAAT	AGTTGTAAAATTCCTTTGTAATTCAAAAGAAACATC
ATTTTAATAGCACAATTTGTATTGTAAAT	AAACCTTTCAAAAACTCCTGCCTTGCAATTACAGCT
ATTTTAATAGCACAATTTGTATTGTAAAT

>NZ_AP019831|2|2|1151601-1153889|CRT
ATTTTAATAGCACAATTTGTATTGTAAAT	TCCAATTAGGGTGGTTAGATTATAACATAGAATATT
ATTTTAATAGCACAATTTGTATTGTAAAT	TTGAAAGAGGCTAATGCGGCAGTTATAAGAATCAAT
ATTTTAATAGCACAATTTGTATTGTAAAT	ATTACTTGAGTTAGGAATTGAGCATAAGGACAAATA
ATTTTAATAGCACAATTTGTATTGTAAAT	GTTTTCGTTAGAGTTTTCAGGGACTTCATTTCTTCC
ATTTTAATAGCACAATTTGTATTGTAAAT	GTACACCATTCATAACGAATAGGCATTTTTCATCAGC
ATTTTAATAGCACAATTTGTATTGTAAAT	ATGGAAACAGTTTATGCAATGCTTGGTAAAATGAAT
ATTTTAATAGCACAATTTGTATTGTAAAT	GATGATGTTTAGAACACAAGCTCATAAATGGTGTTT
ATTTTAATAGCACAATTTGTATTGTAAAT	TTTCGTTTCCTAAATCATCAAAAATAACTAAATCA
ATTTTAATAGCACAATTTGTATTGTAAAT	CTCTGATTTTCCTATCCATTATCCACCACCTCTCCC
ATTTTAATAGCACAATTTGTATTGTAAAT	TTATATATGCTAGAGTCAGCACAGAAATGCAGGAAG
ATTTTAATAGCACAATTTGTATTGTAAAT	CTATTTTACTTTTAACGGTTTAAAAGCATTTGGTCT
ATTTTAATAGCACAATTTGTATTGTAAAT	TCAAATATATTGAATACGGACCAGTTCATTAATTAT
ATTTTAATAGCACAATTTGTATTGTAAAT	TAAAAATTTATAAATAAATTTAAATCATATTTATTA
ATTTTAATAGCACAATTTGTATTGTAAAT	TTTTTATCGCTAAATACTATTTTTATACAATTTTCT
ATTTTAATAGCACAATTTGTATTGTAAAT	GAACATTGATAGAGAAATAAAATAACTCTTTACAAAT
ATTTTAATAGCACAATTTGTATTGTAAAT	TGCTACTGTTAAAATTGAACTAATAGGAGGATTGAA
ATTTTAATAGCACAATTTGTATTGTAAAT	TAAAAACAAGGCTTTAGAATACGGGGGAGTAGATAA
ATTTTAATAGCACAATTTGTATTGTAAAT	CTCCTAAATAATCTTTTTGTTTATTGTTTGCAGGTT
ATTTTAATAGCACAATTTGTATTGTAAAT	TTTGATTTAGATAAAAGGTTGCAGACAATTGTAATC
ATTTTAATAGCACAATTTGTATTGTAAAT	AATCTTCTGCTAATGATTGAAACAGGAACATTTTTT
ATTTTAATAGCACAATTTGTATTGTAAAT	AATCCCCTAATAATAAAGGTTTTGTTGGTCTTACAAC
ATTTTAATAGCACAATTTGTATTGTAAAT	TTAGGATGTATTTTTGTTATCTCTGCTATTAAAGAAG
ATTTTAATAGCACAATTTGTATTGTAAAT	TTTGCTGTGCCAACTTCTGATATAGAACTTTTGAAA
ATTTTAATAGCACAATTTGTATTGTAAAT	CATCTTTGAAAAATAAATAACAATATTCTTTATACT
ATTTTAATAGCACAATTTGTATTGTAAAT	GTGGATTAATCGTTTTTTGTGGAAAAAAGGAGGGTG
ATTTTAATAGCACAATTTGTATTGTAAAT	TTTATTGTGTTTTTCATTTCTACACCTCTTTACTTA
ATTTTAATAGCACAATTTGTATTGTAAAT	TTATTCTCATTGAACGTTCCAGGTCCTTCTAAAGT
ATTTTAATAGCACAATTTGTATTGTAAAT	GAAAAAATGTGGGAAGAATTGACGGAAAGAGCGGAA
ATTTTAATAGCACAATTTGTATTGTAAAT	TTTAATACTCCCTTATTTCATTTTTACCCCCTTTTGA
ATTTTAATAGCACAATTTGTATTGTAAAT	ATGATTGAAACAGGGCATTTCAAGAACAATATCGCC
ATTTTAATAGCACAATTTGTATTGTAAAT	TCGCTACAATGATAAGCGATGTGTCAGATAACGAGA
ATTTTAATAGCACAATTTGTATTGTAAAT	AGCTCATAAGTGATTGTGAGTTTGGATAAGATATTA
ATTTTAATAGCACAATTTGTATTGTAAAT	AGTTGTAAAATTCCTTTGTAATTCAAAAGAAACATC
ATTTTAATAGCACAATTTGTATTGTAAAT	AAACCTTTCAAAAACTCCTGCCTTGCAATTACAGCT
ATTTTAATAGCACAATTTGTATTGTAAAT	TACATTTTACCCTTGACT
ATTGCAAGCATAATTTGTAAATTGTAAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019831.1\|WP_155282661.1\|1149598_1150087_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NZ_AP019831.1\|WP_021743260.1\|1156758_1157196_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_026749139.1\|1143711_1145481_+\|CRISPR-associated-protein-Cst1	cas8b2	cd09665_cas8b2_CAS-I-B	gnl\|CDD\|187884
NZ_AP019831.1\|WP_155282665.1\|1162450_1162960_-\|DUF1439-domain-containing-protein	unknown	unknown	gnl\|CDD\|377799
NZ_AP019831.1\|WP_155282662.1\|1154878_1155859_+\|3-phosphoglycerate-dehydrogenase	unknown	unknown	gnl\|CDD\|240639
NZ_AP019831.1\|WP_155282663.1\|1157809_1160950_+\|DNA-polymerase-I	unknown	unknown	gnl\|CDD\|235591
NZ_AP019831.1\|WP_026749134.1\|1150123_1151116_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|187853
NZ_AP019831.1\|WP_146996454.1\|1155979_1156624_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370129
NZ_AP019831.1\|WP_026749140.1\|1142904_1143687_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam01881_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
NZ_AP019831.1\|WP_155282667.1\|1163968_1164697_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224051
NZ_AP019831.1\|WP_026749142.1\|1137335_1139996_-\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
NZ_AP019831.1\|WP_146996452.1\|1154046_1154775_+\|HAD-IB-family-hydrolase	unknown	unknown	gnl\|CDD\|273654
NZ_AP019831.1\|WP_026749138.1\|1145483_1146380_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|274215
NZ_AP019831.1\|WP_026749141.1\|1140054_1140459_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_155282666.1\|1163238_1163976_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223836
NZ_AP019831.1\|WP_155282664.1\|1161050_1161821_+\|AzlC-family-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|377070
NZ_AP019831.1\|WP_026749127.1\|1161843_1162152_+\|AzlD-domain-containing-protein	unknown	unknown	gnl\|CDD\|377512
NZ_AP019831.1\|WP_026749133.1\|1151117_1151396_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NZ_AP019831.1\|WP_026749136.1\|1147180_1149580_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|273707
NZ_AP019831.1\|WP_026749137.1\|1146382_1147147_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|273860

Protein	Function_ID	Function_description	E-value
NZ_AP019831.1\|WP_155282661.1\|1149598_1150087_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	5.38033e-56
NZ_AP019831.1\|WP_155282666.1\|1163238_1163976_+\|ABC-transporter-permease-subunit	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	4.12299e-57
NZ_AP019831.1\|WP_026749139.1\|1143711_1145481_+\|CRISPR-associated-protein-Cst1	gnl\|CDD\|187884	cd09754, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as CXXC_CXXC family.	8.79429e-14
NZ_AP019831.1\|WP_155282665.1\|1162450_1162960_-\|DUF1439-domain-containing-protein	gnl\|CDD\|377799	pfam07273, DUF1439, Protein of unknown function (DUF1439). This family consists of several hypothetical bacterial proteins of around 190 residues in length. Several members of this family are annotated as being putative lipoproteins and are often known as YceB. The function of this family is unknown.	0.00333733
NZ_AP019831.1\|WP_155282662.1\|1154878_1155859_+\|3-phosphoglycerate-dehydrogenase	gnl\|CDD\|240639	cd12162, 2-Hacid_dh_4, Putative D-isomer specific 2-hydroxyacid dehydrogenases. 2-Hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	2.59976e-119
NZ_AP019831.1\|WP_155282663.1\|1157809_1160950_+\|DNA-polymerase-I	gnl\|CDD\|235591	PRK05755, PRK05755, DNA polymerase I; Provisional.	0
NZ_AP019831.1\|WP_026749134.1\|1150123_1151116_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	9.95708e-161
NZ_AP019831.1\|WP_146996454.1\|1155979_1156624_+\|hypothetical-protein	gnl\|CDD\|370129	pfam08797, HIRAN, HIRAN domain. The HIRAN domain (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p. The HIRAN domain is found as a standalone protein in several bacteria and prophages, or fused to other catalytic domains, such as a nuclease of the restriction endonuclease fold and TDP1-like DNA phosphoesterases, in the eukaryotes. It has been predicted that this domain functions as a DNA-binding domain that probably recognizes features associated with damaged DNA or stalled replication forks.	5.56733e-06
NZ_AP019831.1\|WP_026749140.1\|1142904_1143687_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	6.56509e-16
NZ_AP019831.1\|WP_155282667.1\|1163968_1164697_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	1.3923e-162
NZ_AP019831.1\|WP_026749142.1\|1137335_1139996_-\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NZ_AP019831.1\|WP_146996452.1\|1154046_1154775_+\|HAD-IB-family-hydrolase	gnl\|CDD\|273654	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490. This hypothetical equivalog is a member of the IB subfamily (TIGR01488) of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. The sequences modelled here are all bacterial. The IB subfamily includes the enzyme phosphoserine phosphatase (TIGR00338). Due to this relationship, several of these sequences have been annotated as "phosphoserine phosphatase related proteins," or "Phosphoserine phosphatase-family enzymes." There is presently no evidence that any of the enzymes in this model possess PSPase activity. OMNI\|NTL01ML1250 is annotated as a "possible transferase," however this is due to the C-terminal domain found on this sequence which is homologous to a group of glycerol-phosphate acyltransferases (between trusted and noise to TIGR00530). A subset of these sequences including OMNI\|CC1962, the Caulobacter crescentus CicA protein cluster together and may represent a separate equivalog. [Unknown function, Enzymes of unknown specificity].	3.60779e-52
NZ_AP019831.1\|WP_026749138.1\|1145483_1146380_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|274215	TIGR02585, conserved_protein, CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This clade is a member of the DevR family (TIGR01875) and includes the DevR protein of Myxococcus xanthus, a protein whose expression appears to be regulated through a number of means, including both location and autorepression; DevR mutants are incapable of fruiting body development.	8.29478e-56
NZ_AP019831.1\|WP_155282664.1\|1161050_1161821_+\|AzlC-family-ABC-transporter-permease	gnl\|CDD\|377070	pfam03591, AzlC, AzlC protein.	1.54089e-20
NZ_AP019831.1\|WP_026749127.1\|1161843_1162152_+\|AzlD-domain-containing-protein	gnl\|CDD\|377512	pfam05437, AzlD, Branched-chain amino acid transport protein (AzlD). This family consists of a number of bacterial and archaeal branched-chain amino acid transport proteins. AzlD is known to be involved in conferring resistance to 4-azaleucine although its exact role is uncertain.	0.00102718
NZ_AP019831.1\|WP_026749133.1\|1151117_1151396_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.72593e-26
NZ_AP019831.1\|WP_026749136.1\|1147180_1149580_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	2.63837e-58
NZ_AP019831.1\|WP_026749137.1\|1146382_1147147_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|273860	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family is represented by TM1800 from Thermotoga maritima. It is related to TIGR01868 (CRISPR-associated protein, CT1976 family).	1.77673e-19

>NZ_AP019831.1|WP_026749133.1|1151117_1151396_+|CRISPR-associated-endonuclease-Cas2
MYIILVYDILTDDNGPRISRNVFKICKKYLTNVQKSVFEGEITPVLLKKLNLELKRYIRKDKDSLIIFKSRQEKWLEKEFWGLEDDKTSNFF
>NZ_AP019831.1|WP_026749134.1|1150123_1151116_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MAESYFIFSNGELKRKDNVVRITAPDGRFKDIKIEVTRDIYLFGEVSLNTKCLNYLAQNKIPVHIFNYYGFYTGTFYPKESNVSGKLFVKQVENYTDNSKRIELAQLIIDAASTNILRNLRYYQERGKDLESVITEIKALKKGIFRTNEINELMGIEGSIRRTYYTAWNTIVNQEIDFEKRVKRPPDNMINTMISFLNTLVYTACLSEIYVSQLNPTISYLHSVGERRFSLSLDIAEVFKPLLADRIIFSLLNKKMITEKDFVKDSNYFYMKENAQKLILKTFNERLETSIKHRDLNRKVSYRHLMRLEAYKLVKHLLEDKKYEGFKIWW
>NZ_AP019831.1|WP_155282661.1|1149598_1150087_+|CRISPR-associated-protein-Cas4
MKITGLMINYYFVCKRKLWCQSKNINLEEENENVQLGKLIDENSYNLETKQVMIEETVNIDFIRKWQVVHEVKKSKAVEEAAIWQVKYYIYFLKRRGIKIEKGIIDYPVIRERKEIILTEEDENTLKEILTDIEKICQNEKAPPVINNKIYKKCAYYEFCYV
>NZ_AP019831.1|WP_026749136.1|1147180_1149580_+|CRISPR-associated-helicase/endonuclease-Cas3
MKNNFLAKSSGETILRHTENLFNNFMKIFMIYPKLNVEKRLLLLACIYHDLGKINQKFQSKLSGEKQSGEIPHGILSTSFINDDILIEYHHFSEDEIKILAHSVALHHERNLMEINDSDLSDEIYSMNNEVKNFSKELKILENIYFEYFKNTENYKDRKAIFNWEDGKVELAELSSLFYEIGSRVYSDVEGSETFQKYVMLKGLLNKIDYAASSYIPVEEKNDFLEEKMNAFLKNVLKKDNPENDWNELQKFMIHNRNKNVVVVAQTGYGKTEAGLLWIGNNKGFFTLPLRVAINAIFDRVKNQIVIEKLENRIGLLHSDFREIYIEDIKKKEKNNLEKMDNDELFMYMDKTKQLSLPLTVCTIDQLFDFVFRAPGFELKVATLSYSKVVIDEIQMYSTDLLAYLIYGLKYITDFGGKFAIMTATLPGIITDLLKKEEIEFVTTEPFINDKKRHNLKVLKEVINAKFIKENYKYNKILVVCNTVKKSKQIYEELKNLGIECKELNLLHSRFIKKDRAEKEKEISEFANPKRFKESVKKERKSKNIFENGIWIGTQVVEASLDLDFDILITELSDLNGLFQRMGRCYRNREILDEKYNCYVFTEECSGIKSSKAVIDKEIHQKSKEALINIDGLLTEKEKLELIDEVYSTESLKDTEYYGKLVKNIYALKNYIVEYEKTKSEVQKIFRNIASRDIIPKIIYQENEKEIKKNIEILQKKAKGLDEEKRKNLRSEKIEARREINQFKVAIPEYEFDDISPEQVEKIEINDYETLIILDCDYSYEKGFEVKMKNQDFFEDNTF
>NZ_AP019831.1|WP_026749137.1|1146382_1147147_+|type-I-B-CRISPR-associated-protein-Cas5
MKAVKLKLYQNMVNYKVPTSFQLKESYPLPPYSTVIGMIHSLCDFKEYKPMKISISGNYFSKVNDLYTRYEFKNGNPFEMGRHQLNVNGYGINRGVATAELLVDVNLTIHIIPEDQSEEFLDIIFEAFKYPREYPSLGRREDIVLIKDVKIVDVEKKKLEKDLSNGEDDFAYIPVNFIQEKLVNYGDKKNGMNIYGTRYELTKNYILNNIGTKSKSKMIRSWEKEEVIYSSNIKGFKRREVPVDTDNEIVFCEL
>NZ_AP019831.1|WP_026749138.1|1145483_1146380_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MKKKGLTFTAIFLAQSANYGEGIGNVAALKKLSRNKGEQYTYISRQAIRYNIIEQLGEEKSPVKAEGSGDKKVVQFSADTTIKDYSELDFFGYMKTIKGENSKNRSAIVRLSNAISLETFKGDLEFLTNKGLADRIGEFPNIAQAEIHKSYYKYTVTIDLDRIGIDELDKIEVSNEEKSRRVRKLLDTISLLYRDIKGRREDLKPLFIIGGVYDIKNPFFENIVDVKNNKILADKLCSGIYDYIEKDTISGIVKEQFENDTEVEEKLKGKNINVLNVPEFFKQLKEKVDNYYTEKVDG
>NZ_AP019831.1|WP_026749139.1|1143711_1145481_+|CRISPR-associated-protein-Cst1
MSNEKIELKLKDWLFNAGLLGFINILGEEAKSSGELEIDNKNRLIKFSPKVLENFEYKYFDFFIKRYGKTLTYGKILEFEKYIDEFEENGEKIKSINELKMINDKITFFKAKIKSESYKKAYDFIEKNGTNKILGLEKELKKIKEPKENIAEISNDDIKNNLKIMKEIIDFFKKKITDKEGNVKNYLAAKNIAYVIINNAWSSVSFLNKANAAKDIYEEYKSYFVEPALEYVNADKSKFKYKCVISNMQMKNYKNTLGFLNDTGFDVSRKPSHVWNFVNDIAVTPLVTLIYSCVPAGFIYGADKGIFVNANHNIDQLCNINNGIAYNILEDESEEKNINLYKNLLKEIKKEKDNTKYELSDIQIVKFEEGHYKFTLLSRNILKLLSENKEKLDDLLDKWYLIDKRYFNLYDTTITELLNNQNLFSLINKLCYYKISKAKLSCKLKNIEDLLKINLDYIRRLKKMDKQEIIEKKENKKTSEELTEKDVFYIRRDAMIFREEYIRKSGNDKKIGSLLYRLQNALRINNVDMFMDALISAHAYAGKNISSLFAKALLNDENFQTLGHGFLLGLLGEDKSKNENKTDKKEGNE
>NZ_AP019831.1|WP_026749140.1|1142904_1143687_+|CRISPR-associated-endoribonuclease-Cas6
MRFKINIELTEGNSFPINWRSKILCVLKTGLKKCDNEIFEEFFGSAKQKNYTWSAYFQNVKFEKDKVKFLGEEKKIIVNLSAYDNVDSLNIYNAFSGIRFKEIKISEETKVVVTNISILPRQIIKDNILIVKTMSPIVCRDHDQETKKDTYYIGTDDKFSKIIKRNLYLKLKELKGEYVKKDIEDLIIDSSQTKKVVVKHYDKTKKDKTLNYENKFNGKFLDTSVGILKLEGKSYILDYIYNAGIGSITGSGFGMLEKLK
>NZ_AP019831.1|WP_026749141.1|1140054_1140459_-|hypothetical-protein
MRKIVIDKRKSVMLVMTCILFMMTYSSLLGTPSFSRKLSVFVDENNLSHEDIRDLIVKINQIESVNNRRLTQELKKIGKRKEKEKGKQKNSLFLLFEKNQNTVFYKNSDKIPKNIGNISAFLMKKDENNLRTRE
>NZ_AP019831.1|WP_026749142.1|1137335_1139996_-|preprotein-translocase-subunit-SecA
MLKKIGEKIFGTSDEREIKKMQKLVDKINEVEPLFEKMTDEQLSHKTVEFKERLQKETLDDILVEAFATVREASKRLMGMRHYDVQLIGGMILHKGCIAEMKTGEGKTLMATLPIYLNALPGKGVHVVTVNDYLAKRDRDIMAGLFEFLGLTSGVVVGNITPDQRKTAYNCDITYGTNNEFGFDYLRDNMVGELDEKVQRGHNYVIVDEVDSILIDEARTPLIISGAAEETTEWYNTFSEVAKRLKRSYKTEEIKDKKNTVIPDEDWEDYEVDEKSHTVTITDKGIKNVERMLKIDNLYSPEYVELTHFLTQALKAKELFKLDRDYIINDDNEVIIVDEFTGRLMEGRRYSDGLHQAIEAKEKLEVAGENQTLATITLQNYFRMYEKLSGMTGTAKTEEDEFKQIYSLKVIVVPTNKPVARVDLPDVIYMNKKAKYKAIARKIEELYHKGQPVLVGTASIQHSEEVSALLKKAKIPHEILNAKHHEREAEIIAQAGRFKTVTIATNMAGRGTDIKLGGDAESFATKVAVKGTPEYEDVHSAYVKECEEDKKKVLAAGGLFILGTERHESRRIDNQLRGRAGRQGDPGTSEFYLSLDDDLMRLFGGDRLKSMMKMLKIDEDEEIRHKQISKSVENAQKRIESRNFSSRKSLIEYDDVNNTQREVVYEQRDAILKNENLKELIINMISDTVDDIVNSAYVGEGNGEKDFNLLSDKLHETFEYEISEELQNASADEISNKVYDDLVRIYDEKEEAIGEEIFRRIERYIMLEVLDSKWRQHLKDLTELREGIRLRSYGQRNPIHDYKIVGYDIYNEMIDAIKRETSSFILKLRVRGEEDTNNLTHEEVSNVRYEHEENEMMGDDVSARTPNEPHRPLSRRERRERERRNV
>NZ_AP019831.1|WP_146996452.1|1154046_1154775_+|HAD-IB-family-hydrolase
MKKNVAAFFDIDGTIYRDSLLIEHFKMLVQYEYIDMMTWEGKVKEKFSKWENRTGDYDDYLDELVQTYMEALKNFSKEDMDFIAKRVMKLKGDKVYRYTRERLKYHKEKNHKVIIISGSPDFLVSKMAERYGVKDYRASTYEVNENGIFTGKVIPMWDAKSKQKAIADFCKMYEIDLTKSYAYGDTTGDLTMFKNVGNAIAINPAKKLLQKIKRDKELKEKVMIVVERKDVIYKLKADVDII
>NZ_AP019831.1|WP_155282662.1|1154878_1155859_+|3-phosphoglycerate-dehydrogenase
MDKNLKIVYLDRITAGPIDLKERFSKYGEYIEYEDTDSGEVDERIKDVDIVITTRIKLGREQFKKAKKLKLILITATGFNHIDVKSANEFGIKVANVSGYSTNSVAQLAITFLLNELTPVNRYYEEVKDGKWMDITVPDYQKYPIDDANGKILGIVGFGNIGKRVAQVAEILGMEVMVAKNTEKDNAKTDSVIEKGGFLRYDLYEVLEKCDVLTLHVPLTDSTRNLINLEKMKKMKKSAIILNLARGPVINQEDLYFALKNKIIKSAAIDVTSVEPIEKNSKLFELDNILVTPHIAWKSEKSMVKLMDDVEENLKLFLEGKLEGLK
>NZ_AP019831.1|WP_146996454.1|1155979_1156624_+|hypothetical-protein
MLINNFSGIKLEFDGLYYGGNYEIEIFPDGRFYYSYIENTSVELKKGSFQINQKEIMIFEEMMDYFELLKNQSNYMINEFNFGNGVLVIQKNNGREEKIRLGKEMMFEYAKTLIDKYTKKSKRLFLLDTYLEGAKYIRNFAIKIKDEVQLDLFREFNGISLNAVAVYNSKKEKVGYLPKNQSEIIARMIDAGKKFVAVPIPYDEDIALKIYLVD
>NZ_AP019831.1|WP_021743260.1|1156758_1157196_+|hypothetical-protein
MGFRLSVKGQENEILLDKESILDVKYISETPDDSNARATDLGVILEIRGKILAAANGDTEDDTRKVAQWSLVPSEASDAYRQASLEIISAGQMVRKIDMTNVFVVDYIEEYGNQAGTGTFSLKIKQKKEKVKEVAIEGGYATQEA
>NZ_AP019831.1|WP_155282663.1|1157809_1160950_+|DNA-polymerase-I
MKRAVILDTSAIMYRSHFALMGMRNSNGMSTGATFGFINTLESVIREFRPDYLVACLDVKRSELDRTGELETYKAHRESMPEELVMQIDTIMKVLDGYRIPKYKKAGQEADDVIATFATKFSNDEDDQIEVFVITGDKDLAQLVDGKINIALLGKGDKNSAFKHIKTDEDVVEYLGVTPDKIPDLFGLMGDKSDGIPGVAGIGPKNGVKLITTYGNLEGIYENIDEIKGKQKEKLLTDKENAFISRELATVKKELDVEYDKNKLKFEEKDFDSLLKLYEELDFKRFSKAVEEEKERFLQSGNQKKLTEEEKQILEKNKKINEEKLEKERLEREKVEKQELEYDKENPIFDGISHFYEHVEYEHNSEIDKKIDEIQILKEKLAIEYEAQKKKAEEIALENQKTEKTKKTKDEKVYFEKNYGKVVSWNDAYSVIKKMDKKVAIFENMLGLSICDEKTNIVLLDSELQDILQNGNQKNAESGAQINLFSLSNNADEKEENKKNVKNIYKLLSEKEIIAYNVKEYMKNGESEYFGYSVGGKTYGINNDRFGIKCTEYFDILLARYVLGTESLQEIEEIILDEFSVEIATFEEQFKKERRKKDFSDVSDDVICEFLSKRTFFIYKLETIFRNRLQNEQFLNIFDKLESRLIPVLAQMEETGIKIDKKYFSEFQNELEQKLSTLENEIHELANEEFNIDSPQQLGEVLFEKLQIPSGKKTKTGYSTNVEVLEMIANNGELTEDKRMIGKKLLEYRAYKKLLSTYIEPIPKLADKEDRIHTTFNQNGTSTGRLSSVNPNLQNIPVRTDDGIRIRTGFIAKEGHSLISFDYSQIELRVLAELSKDRHLVQAYQDNQDLHNLTARKIFFKTEEDEISRHERSIAKVINFSILYGKTPFGLSKELGITVQEASQYITTYFEEYPRVRKFLDIVTETAKLHGFVETFYGTRRYISGINATNKNVQAQAVRMAVNTVVQGTAANIIKKVMIELHEEFKNDENIKMLLQVHDELIFEVRDEFAKEYMEKIEKIMENTVKFKKVPLKANGSVAKNWGLLK
>NZ_AP019831.1|WP_155282664.1|1161050_1161821_+|AzlC-family-ABC-transporter-permease
MAQIRKLESYLKGLKDGTGIGIAYIPFGVAIGLISAKSFSQILPMIGLTSFGMYAGGAHSLLLKVLYVMKSPPVEVILSIALINLRYLLLNIVIFRQLGEKTPIFQKFLVGVGLTDETVTYLTLKKAKNSWYMMGVNTIPYFCYCFGTIFGAIFGEKLPESLMTSMNFVLYSIFFSMLIMALSQNFKYIKIVLLALIIKMAFTFLPILNKISSGWVMILTMFLASFIYAQLYYNENPEKQENDEIDKGKGSDKIEL
>NZ_AP019831.1|WP_026749127.1|1161843_1162152_+|AzlD-domain-containing-protein
MILMTLIIMTVILRTLPIFVKIPENNLKVNKFFEALPYTVLTVLVFPDIFTSTGSTNFDIIRVLIGMAIVAYLTFRKTNLGIIIIVSIAVIYFLGTLKIYLK
>NZ_AP019831.1|WP_155282665.1|1162450_1162960_-|DUF1439-domain-containing-protein
MKLFKFLFFSIIILIAGLGYYIYTQNQLKIPDSMVKSAVASKFPIEKSYPLGKIKLFNPKVNFENDKLIIEAEYLNDALNDQISGTMTFATDIRYDPMKSNLYLEDFQIVKLTKENKEIDLDKKPIIRTGLNYAFSQLEKKEILNLSGVEKFQMIKDIKIENNKLTVVK
>NZ_AP019831.1|WP_155282666.1|1163238_1163976_+|ABC-transporter-permease-subunit
MEELEKTRKIVKTSFFIAVVTVAALLAFPYDMKPKEWEIYAGSYFVTTLGLTVGGAAIGILFGMLLAFFKFQKTKSETVNMIKDVVIDEYVDIMRGTPMVLQLLTLSFVVVIFNNYWIALIALGLNSAAYVEETIRSGIESIDKGQMEAARATGMPYRMAMNEIIMPQAIKNILPALLNEFINLFKETAVVGYISVVDITMNSKSLQAVYYSVKPILFTGLVYYISVKLFSFIGKRLEMRLKEND
>NZ_AP019831.1|WP_155282667.1|1163968_1164697_+|ATP-binding-cassette-domain-containing-protein
MIKIKNLKKKYGELEVLKGISTEIKEGEVISIIGPSGSGKSTFLRCINRLEEPTSGEITINNKNILERGVDINKIREEVGMVFQHFNLYPHKTVMENITLGPIRLKKMSKDEAEKLAMELLEKVGLSDKRDVYPNKLSGGQKQRVAIARALAMNPKVILFDEPTSALDPEMIGEVLEVMRELANAGMTMIVVTHEMGFARNVANRVFFMDEGYILEDAKPQDLFDNPKSERARIFLDKVLNH

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Crispr_ID: NZ_AP019831_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019831_3

1341592-1342222

TypeIII-A?,TypeIII-D

I-B

Consensus_repeat	Method
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	PILER-CR
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	CRISPRCasFinder
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	CRT

8 spacers

The CRISPR arrays of NZ_AP019831_3

>merge|NZ_AP019831|3|1341592-1342222|PILER-CR,CRISPRCasFinder,CRT
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACCGTTAATATTTCCACTCCGAATGGCCGTGGTGTAAGTATTGTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACATTCCAAAATTATCTGAACATTGCTTTGAAACAATAGTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACTTAATGAAGAACGGATGGAAACAGACGACGTTAAAGGTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACATTGAAACATTAGTAAAGGAAGGTGTGATTATTAATTGTAGTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACAGGATCAGCGATTTCGTTGTTGCCGTTTTCCACAACGTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACTTTTTTTCGTACACTAGATCATCGATCTTTCGATCTGTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACCGACCTGATCTAGTTCTAACTAATGCAGAAACGATTAGTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAACAGTTTTATAACAACTCTTATTCCTTCCCTGTCTGACTGTTAAAGTAAGTTATCCATTAAAATAAGGTTTAGAAA

>NZ_AP019831|3|3|1341592-1342148|PILER-CR
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	CGTTAATATTTCCACTCCGAATGGCCGTGGTGTAAGTATT
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	ATTCCAAAATTATCTGAACATTGCTTTGAAACAATA
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	TTAATGAAGAACGGATGGAAACAGACGACGTTAAAG
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	ATTGAAACATTAGTAAAGGAAGGTGTGATTATTAATTGTA
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	AGGATCAGCGATTTCGTTGTTGCCGTTTTCCACAAC
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	TTTTTTTCGTACACTAGATCATCGATCTTTCGATCT
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	CGACCTGATCTAGTTCTAACTAATGCAGAAACGATTA
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC

>NZ_AP019831|3|3|1341592-1342222|CRISPRCasFinder
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	CGTTAATATTTCCACTCCGAATGGCCGTGGTGTAAGTATT
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	ATTCCAAAATTATCTGAACATTGCTTTGAAACAATA
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	TTAATGAAGAACGGATGGAAACAGACGACGTTAAAG
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	ATTGAAACATTAGTAAAGGAAGGTGTGATTATTAATTGTA
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	AGGATCAGCGATTTCGTTGTTGCCGTTTTCCACAAC
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	TTTTTTTCGTACACTAGATCATCGATCTTTCGATCT
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	CGACCTGATCTAGTTCTAACTAATGCAGAAACGATTA
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	AGTTTTATAACAACTCTTATTCCTTCCCTGTCTGACT
GTTAAAGTAAGTTATCCATTAAAATAAGGTTTAGAAA

>NZ_AP019831|3|3|1341592-1342222|CRT
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	CGTTAATATTTCCACTCCGAATGGCCGTGGTGTAAGTATT
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	ATTCCAAAATTATCTGAACATTGCTTTGAAACAATA
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	TTAATGAAGAACGGATGGAAACAGACGACGTTAAAG
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	ATTGAAACATTAGTAAAGGAAGGTGTGATTATTAATTGTA
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	AGGATCAGCGATTTCGTTGTTGCCGTTTTCCACAAC
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	TTTTTTTCGTACACTAGATCATCGATCTTTCGATCT
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	CGACCTGATCTAGTTCTAACTAATGCAGAAACGATTA
GTTAAAGTAAGTTATCCATTAAAACAAGGATTGAAAC	AGTTTTATAACAACTCTTATTCCTTCCCTGTCTGACT
GTTAAAGTAAGTTATCCATTAAAATAAGGTTTAGAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019831.1\|WP_155282726.1\|1332806_1333649_-\|metal-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224033
NZ_AP019831.1\|WP_155282733.1\|1344696_1347774_+\|translation-initiation-factor-IF-2	unknown	unknown	gnl\|CDD\|235401
NZ_AP019831.1\|WP_155282735.1\|1352575_1353805_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	unknown	unknown	gnl\|CDD\|235422
NZ_AP019831.1\|WP_146996571.1\|1347796_1348165_+\|30S-ribosome-binding-factor-RbfA	unknown	unknown	gnl\|CDD\|376719
NZ_AP019831.1\|WP_155282728.1\|1336039_1337632_+\|phosphoglycerate-dehydrogenase	unknown	unknown	gnl\|CDD\|237436
NZ_AP019831.1\|WP_155282730.1\|1340147_1341041_+\|homoserine-kinase	unknown	unknown	gnl\|CDD\|234920
NZ_AP019831.1\|WP_026748983.1\|1341085_1341250_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_018450081.1\|1351609_1352185_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
NZ_AP019831.1\|WP_155283258.1\|1344178_1344700_+\|DUF448-domain-containing-protein	unknown	unknown	gnl\|CDD\|225350
NZ_AP019831.1\|WP_155282736.1\|1353872_1356239_+\|endopeptidase-La	unknown	unknown	gnl\|CDD\|223542
NZ_AP019831.1\|WP_155282732.1\|1342863_1344057_+\|transcription-termination/antitermination-protein-NusA	unknown	unknown	gnl\|CDD\|237061
NZ_AP019831.1\|WP_026748986.1\|1335423_1335780_-\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|223806
NZ_AP019831.1\|WP_146996574.1\|1350013_1351300_+\|trigger-factor	unknown	unknown	gnl\|CDD\|234956
NZ_AP019831.1\|WP_155282731.1\|1342375_1342864_+\|ribosome-maturation-factor-RimP	unknown	unknown	gnl\|CDD\|234627
NZ_AP019831.1\|WP_155282725.1\|1330801_1332712_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|275228
NZ_AP019831.1\|WP_155282724.1\|1329751_1330789_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_155282734.1\|1348258_1349956_+\|single-stranded-DNA-specific-exonuclease-RecJ	unknown	unknown	gnl\|CDD\|273193
NZ_AP019831.1\|WP_155282727.1\|1334441_1335383_-\|zinc-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238500
NZ_AP019831.1\|WP_155282729.1\|1337757_1340055_+\|autotransporter-protein	unknown	unknown	gnl\|CDD\|371915
NZ_AP019831.1\|WP_155283257.1\|1333691_1334390_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224046

Protein	Function_ID	Function_description	E-value
NZ_AP019831.1\|WP_155282726.1\|1332806_1333649_-\|metal-ABC-transporter-permease	gnl\|CDD\|224033	COG1108, ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism].	1.65505e-48
NZ_AP019831.1\|WP_155282733.1\|1344696_1347774_+\|translation-initiation-factor-IF-2	gnl\|CDD\|235401	PRK05306, infB, translation initiation factor IF-2; Validated.	0
NZ_AP019831.1\|WP_155282735.1\|1352575_1353805_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	gnl\|CDD\|235422	PRK05342, clpX, ATP-dependent Clp protease ATP-binding subunit ClpX.	0
NZ_AP019831.1\|WP_146996571.1\|1347796_1348165_+\|30S-ribosome-binding-factor-RbfA	gnl\|CDD\|376719	pfam02033, RBFA, Ribosome-binding factor A.	6.29321e-23
NZ_AP019831.1\|WP_155282728.1\|1336039_1337632_+\|phosphoglycerate-dehydrogenase	gnl\|CDD\|237436	PRK13581, PRK13581, D-3-phosphoglycerate dehydrogenase; Provisional.	0
NZ_AP019831.1\|WP_155282730.1\|1340147_1341041_+\|homoserine-kinase	gnl\|CDD\|234920	PRK01212, PRK01212, homoserine kinase; Provisional.	5.69442e-103
NZ_AP019831.1\|WP_018450081.1\|1351609_1352185_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	7.03625e-135
NZ_AP019831.1\|WP_155283258.1\|1344178_1344700_+\|DUF448-domain-containing-protein	gnl\|CDD\|225350	COG2740, COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination [Transcription].	6.40266e-09
NZ_AP019831.1\|WP_155282736.1\|1353872_1356239_+\|endopeptidase-La	gnl\|CDD\|223542	COG0466, Lon, ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones].	0
NZ_AP019831.1\|WP_155282732.1\|1342863_1344057_+\|transcription-termination/antitermination-protein-NusA	gnl\|CDD\|237061	PRK12327, nusA, transcription elongation factor NusA; Provisional.	8.49773e-143
NZ_AP019831.1\|WP_026748986.1\|1335423_1335780_-\|transcriptional-repressor	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	1.86944e-19
NZ_AP019831.1\|WP_146996574.1\|1350013_1351300_+\|trigger-factor	gnl\|CDD\|234956	PRK01490, tig, trigger factor; Provisional.	4.29122e-122
NZ_AP019831.1\|WP_155282731.1\|1342375_1342864_+\|ribosome-maturation-factor-RimP	gnl\|CDD\|234627	PRK00092, PRK00092, ribosome maturation protein RimP; Reviewed.	5.87018e-40
NZ_AP019831.1\|WP_155282725.1\|1330801_1332712_+\|AAA-family-ATPase	gnl\|CDD\|275228	TIGR04435, ABC_transporter, restriction system-associated AAA family ATPase. Members of this family are AAA family ATPases by homology. They occur regularly in a conserved gene neighborhood with the restriction (R), modification (M), and specificity (S) proteins of an apparent type I restriction enzyme system, plus one additional uncharacterized protein. It is not clear whether members of this family contribute to restriction per se, or to another process such as transfer of mobile elements.	4.64071e-09
NZ_AP019831.1\|WP_155282734.1\|1348258_1349956_+\|single-stranded-DNA-specific-exonuclease-RecJ	gnl\|CDD\|273193	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ. All proteins in this family are 5'-3' single-strand DNA exonucleases. These proteins are used in some aspects of mismatch repair, recombination, and recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	5.45013e-134
NZ_AP019831.1\|WP_155282727.1\|1334441_1335383_-\|zinc-ABC-transporter-substrate-binding-protein	gnl\|CDD\|238500	cd01018, ZntC, Metal binding protein ZntC. These proteins are predicted to function as initial receptors in ABC transport of metal ions. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. They are comprised of two globular subdomains connected by a long alpha helix and bind their specific ligands in the cleft between these domains. In addition, many of these proteins possess a metal-binding histidine-rich motif (repetitive HDH sequence).	3.10766e-67
NZ_AP019831.1\|WP_155282729.1\|1337757_1340055_+\|autotransporter-protein	gnl\|CDD\|371915	pfam12138, Spherulin4, Spherulation-specific family 4. This protein is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 250 and 398 amino acids in length. There is a conserved NPG sequence motif and there are two completely conserved G residues that may be functionally important. Starvation will often induce spherulation - the production of spores - and this process may involve DNA-methylation. Changes in the methylation of spherulin4 are associated with the formation of spherules, but these changes are probably transient. Methylation of the gene accompanies its transcriptional activation, and spherulin4 mRNA is only detectable in late spherulating cultures and mature spherules. It is a spherulation-specific protein.	1.00274e-31
NZ_AP019831.1\|WP_155283257.1\|1333691_1334390_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224046	COG1121, ZnuC, ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism].	8.47219e-71

>NZ_AP019831.1|WP_026748983.1|1341085_1341250_+|hypothetical-protein
MAIIVKKGELAKINKGMSQKGFAERCTYTVKEFPKSNLSKKAEEALNKIFSSMK
>NZ_AP019831.1|WP_155282730.1|1340147_1341041_+|homoserine-kinase
MGLKFKVKVPGTSANIGVGYDCLGVALDYFLELEVEESDKIEFLENGEPFSIPIEENLIFEAIKYTEKHLVKNIPSYKVNIVKNDIPIARGLGSSSSAIVAGILIANKFAGDVLDINEVAKLAVEMEGHPDNVVPAIFGGMVLTAHDKENLVYSSLINSDDLCFYVMIPDFKLSTEKARSVLPKMYLVSDAINNISKLGLLVNAFNKGEYDNLRFLLGDKIHQPYRFALINDSEKIFEASKKHGALGEYISGAGPTLISLNYDNEEFLENMKKELAELSDNWTIEKKKINLKGAEVY
>NZ_AP019831.1|WP_155282729.1|1337757_1340055_+|autotransporter-protein
MNKKEISYDFLEISNKCINRAVKEETFTKKIKKAGKKTNYSSVKYKLEIKKESKNIFNKKFGNIVNKKIVSDKRIIVTSLMTGIASLLNAESTETLKPSGYTVNYMANTGTDEKIDKKSNFENAENVLISQNLNKTVANNEKLDKIKVRAATKEDNIRFSFNTKFDMLLSKRNSKNGADSSNNLKSTGNASSAPSNSSSGIGTSSTQLTPSTQTTRVINQQILIPMYKYPHLNDPYWQQVTNMGGSKIPYVVVNPASGPGTAVDSNYVRQISSNINSGIKNIAYVATGYQSRSTADIMADIDKYGSLYGMSNFSGVFLDEVASGTDANARYMENVYKSIKSKYPNLMVVGNPGKSITDSIAPYSDIFVTKEVSANTYLNNYHAPTSAFENNPANANRIMHIIYGATPAQYDEIIRLSRERNVGWLYIVNDTNYNNLPTNFSSLVDNINTPLVVPVLSQNSNKLMTRVISPSASSTQVPLEAPRSKVNLDLVKNVKSSIFQNLQNTEEGKTDIDFTFIGNFSTDYKDKKSSVEYDSDSRGILISLMKNFGKFTVGGGMGYQDSKVNYKGNFEGIDEKIKSHQFILSGKYEFNENIDLTNVLTYSGNSHKFKTETGAGLMNNVKYKSRILDYTTKLGYKFSIDNGFVKPYIGLAAIRVFEGKMDKLNISESTKSGLEWLFGVYAEKTIGQFDIFGKAEYELRGKKGSYHGERKYGNYKIAPLSYSRGVFNAELGTNYKINDYVKASLGYGLADSKNSSIKLGLEASF
>NZ_AP019831.1|WP_155282728.1|1336039_1337632_+|phosphoglycerate-dehydrogenase
MYRVLVGEYIDDEAIAGLQEARDVKVDVKVGISREEILDIIGEYDALIVRSVIKVDKELLDKAKNLKIVGRAGNGTDNINIPEATAHGVIVANTPDSNTVSACEIAIGLMIASARNIVAANNFIKSGKWEREIFVGNELFEKTLGIIGLGRIGGLVATRMKAFGMKLVAYDPYISDERFKRYSCEKAKTLDELMEKADVITIHTPKTKETVDMINAENLHKLKDGVRLVNAARGGLFNEEAVAEGLKSGKIASFGYDVHTVEPRSECILYEFENAITTPHIGATTYEAQRNVGTQVVKQVLNGLRGEIVETAVNLPAIGREEFLIVKPFINLAEKLGKIYFQIEKTPITNVVLNYYGEIAEQETALVDSTAIKGILEPVLKEEVNYINSKPLAEKRGINISINKKERKYKNYSSAIEFVITNEEGKKIYVVGTIGMNNEERIISIKNHDVDMAISDNMIYLGNDDVPGVIGAVGATLGKENINIATMNVGRRENSAIMLLTVDSEVGGKSLKELRGLSQIKWAYYLDLTI
>NZ_AP019831.1|WP_026748986.1|1335423_1335780_-|transcriptional-repressor
MKLTKKRQKIFELVQASNNPVNAKFLKSQVDFDLSTVYRALEFLEKNNYIFSFDFENEKYYFKEENANFFICDSCKHIETVPEFSNEETEKEKSELKKRGFSLLSHLSIFKGKCNDCD
>NZ_AP019831.1|WP_155282727.1|1334441_1335383_-|zinc-ABC-transporter-substrate-binding-protein
MKKLLSLLLLSALFIFSCGNKSETKKEQGITAEAKEKIVTSVPPLRWITQKIAGDDFEVISIVQPNMNHELFEPKPSDLKILENSKVFFTYNMLGFEETISDSLSDKNKIVNVLDGVDKNLFIKGDHDHDHEHEHGHEHGKKEEHEHHHEHEGHGGIDPHVWFSLDMMPKIAENIKNELSKLYPEKKETFEKNYNAFITELNQVKAELSQKMASKTKKSFMIYHPALNYFLKNYAIEEISIEQEGKEPSAQQIKEIIDEAKEHNITTILVQPQFPKQSAEAISKEIPNSKVAEFNVDKENVFENLKQFVDYLN
>NZ_AP019831.1|WP_155283257.1|1333691_1334390_-|ATP-binding-cassette-domain-containing-protein
MTNGQNKKLVSVQNLNFKYNNDYILNDINLDIFKGKNVAILGRNGGGKSTLVKVMLGFLRKNSGSIEFFTSENKIGYLPQIREFDTSFPINIFDLVISGLTNKNNLFRRFNNEEKKRAEILLKEFDIFHLKNKLINEVSGGQLQRALIARALISSPELIFLDEPESFLDKEFEFKLFEKIKELSDSTIVVISHELEKIYDYIDSIFVVEGNIQVYEKKEDYVCSNPYLHSHK
>NZ_AP019831.1|WP_155282726.1|1332806_1333649_-|metal-ABC-transporter-permease
MEFIKIFEYAFMRNALIVGLLSSICCGIIGTYIVNKKMVFISSSISHASYGGIGIGIYLIYFFNLPIKDPLFFGLIFSILSGVLILVLKDTLHVDGDLGIGIVMSMGMAIGIIFAFLTPGYQSDMSTYLFGNILLSNTLNIILLLILDIITITFFIIFYKSIVYTSFDENFYKIHSVPVTFINYFMIILISSVIIINIKTIGIILIISILTIPQAIAASLARKYSTIIILSIIFSFIGILSGLYFSYTLNIPSGPSIIVLLTILLALVKIWGFVKGKFLN
>NZ_AP019831.1|WP_155282725.1|1330801_1332712_+|AAA-family-ATPase
MFPIYMYVKEYKGLKDFEITFDNNYEIKYNRDKDTLSINKKCESANNNIENFYSINKTKGNIDSVNLLIGKNGSGKTSILEMLNMSYFEKKKRKSYFDKLEIEINYMILYKSSKDDENFIFEERYIAKKFTKRKEIEEIRIQEEIYKSQDDGNYIENTGVLKFSFKEKIMKAAMREAKFEQKNIGGLNKLTLYKLNIGLENGSKGKIYNYLVNVNKGENFENSYLTLQIPNLYEAEKIKQIKDKIIDVNSNERIDDFIRLYDINKNNLKDTILNTYFNFIYSEIIWKNLRENSKTKKELKERKKELLKLLNNESSVYRKFEILLEEYENSINNIIKINKEKYRIIEKVADLIDNIVSKIESENEMDIENKDEIIRKFKISCKKENKEVLELLKEYDDFYIPKIERDLIDFGNSLFKEVEFIKIEEEGLSDGEKVKLGYFSTLYSILNGEFKNKKYVTLLFDEVETYLHPEWSRRFLYELIEELGRYEDKKFKLIFATHSPFLIADVLAKDCIYLSKNKKGKIKAEIKEDVKTFGANIIDLFKNTMFLESTFGKFATEKIKGLVDKIEKAEKYSDIKSEVDFIIDEIGEKLISNKLKSMIKSKFENKDEEYYRKKIEEYQAKLDELEKKENNRNSKK
>NZ_AP019831.1|WP_155282724.1|1329751_1330789_+|hypothetical-protein
MIKIDVDERKWEKIKEEHSEWYSDNILPNIKNAYEFIESQKSKSYSIKKYLELLKKIIDKGKDFIIQKELFLDYENKEIDKIIKIMKKKNKKRKSILEIRFEKLNISEEYLPNQLFCYKKFQDGNKNWGRHKLLFLMEIEVCPYCQRNYISSYEENNSKKTTADLDHFYPKSLYPFLALSLYNFIPSCQICNSRFKGNKDTRDSVYLYEEGFDELGVKFRTSKEVISEILGERYSDFYVKIDYENLKNKEDGEKVKNSIENLGLDRVYKKSHNQYIQNLLYNIEKYPENYLENCVEMFESNVDKKKQLEEYFKDIVKEPYRKRIENGEPLAKLTKDILEEFNIKI
>NZ_AP019831.1|WP_155282731.1|1342375_1342864_+|ribosome-maturation-factor-RimP
MEQILDEFEKKIEQHLKKMNLELADLEYVRDGGYNYLRVYVEKMDGTTTLDDCIDFSREIDGIADEMIQEKFFLEVSTPGVERRLRKPKDFVRFLGARINVQTRSNIEGAKRFLGKLEKFEDNTIFLLDDKLAKIVEIPLSKLKKANLIYELPNGILNSEEE
>NZ_AP019831.1|WP_155282732.1|1342863_1344057_+|transcription-termination/antitermination-protein-NusA
MKGRDQKIFLEALDELEKEKGILKEELLETIETALLAAYKKNYGEKDNVKVTINRNSGDVKVYSQRLIVENVENLDEEISLEDAISVKKRAKLGDILDLEINAESFKRNAIQNAKQIVVQKVRECEKRNIFNKFKEIENSIVSANVRKTDEKGNLYVDINGLEAIVPAKELSPVDIFRQGDRIKIYIGAVEESTKFTKTFVSRKSEELLRGLLELEVPEIYEEIIEIRNIAREAGSRSKVAVYSNDKNLDVKGACIGRNGMRIQNIIDELCGEKIDVVLWNEDITEFVKNALNPAEVLSVEIIEEGEENMKVARVLVAENQLSLAIGKKGQNSRLAARLCGVKIDIHTEAAEIEKYEENTAFNDSFEDEIENVGETSDSNDDYEVEESAFAGLHEEE
>NZ_AP019831.1|WP_155283258.1|1344178_1344700_+|DUF448-domain-containing-protein
MCICCRKKGEKSDFLRIAEQDGKYAFDKEMKMQARGFYVCKTNECIERLSKHKKYNIEMEQLVQMLEEVKKQKKNIIDILKPMKNSEYFVFGIDEVFEGIKREKIKLVIIPADIKAKYIDEFEKLKKKFNFEIIFIKKKEELIRLFSRDVNVIGIFNKKVIKGILSKVEVMNG
>NZ_AP019831.1|WP_155282733.1|1344696_1347774_+|translation-initiation-factor-IF-2
MKVHELAKENGFTATKFMEEIRKFGIDKKHHMNVLSDEEVSLIRKKLQKGIQNNQNNGKTENLNKSENKTTESTKENIVKMVSSHSDSQKNNNAEHSKISEHKNINKNYEKPKQPLEKDIKLNVEKKSDNSNINKSNLNNTKNLDNNKNQKFEKPNRFDKKENNKKMEMKVNLSSQNNKANELNREKQSFQNRDSRDSKDNRENGGRNFQNRDNRNREDRKEGFRKEGRDNFRRDNRNFNKDGNNQTRDNRDNRGFQNRDRDNQSGSRNFQSRDNRNREDRKEGFRKEGRDNFRRDNRNFNKDGNNQARDSRDNRGFQNRDRDNQSGGRNFRDRQDNRGFSDRGGFNKDRDDFRKDSRNFSNAKKETSSEIPAATVAEKGKAGGKGKGKFDKKKYEKNRRDREQQEKELRSDFRKDDKKKKKNKKQEKVVKDEIVRIEGESIGMITIGEEIVIKDLAEKLGINVSDIIKKFFMEGKLLTANAILSFEEAEEVALEYEVIVEKEVIEEISYGEKYQLEQEDTADELVTRAPVITIMGHVDHGKTSLLDALRHTNVMSDEAGGITQKIGAYQVNWKGQRITFIDTPGHEAFTEMRARGANITDISILIVAADDGVKPQTVEAISHAKEAGVPIIVAINKIDKPGADPMKVRTELTEYGLMSPEWGGTTEFVEISAKQKINLEELLETILITAELEELKANPNKRPKAVVVESRLDPKMGAVADVLVQEGTLKIGDVFVAGEAHGRVRSMLDDRGKKINKAIVSQPVEITGFNVVPNAGDILYGVESDKQAKKIVEDFIREKKVNDQNKKKHISLESLSQELEEQELKELKCIIRADSKGSVEALRESLEKLNTEKVVINIIQGSAGAVSEGDVKLAEVSNAIIIAFNVRPTTPARIIAEKTGVEIRNYNVIYHATEEIEKAMKGMLDPEYKEVYYGRIEVKQVFKVSNVGNVAGASVVDGKVTKDSKIRVIRDGIIIFNGELGSLKRFKDDVKEVVTGQECGIGIQDFNDIKAGDIIESYIMEEIPR
>NZ_AP019831.1|WP_146996571.1|1347796_1348165_+|30S-ribosome-binding-factor-RbfA
MNDRRKRGLEKEISRIIGMTLLTDIKNDKIKNLVSIHKVELTKDGRYLDLTFSVLDLKDNINKEKIAEDLNKLKGFFRKKIGSQLSIRFVPEVRIHLDDSVEYGVKIASILNEIKKENDNIE
>NZ_AP019831.1|WP_155282734.1|1348258_1349956_+|single-stranded-DNA-specific-exonuclease-RecJ
MKWELKSYNEDYLTSKSSEFGESRLISRLLLNRGIDTEEKVSKFLNSDKGDIHNPFLFENMEKVVERIKKAGRNKEKIVIYGDYDVDGISGVAYLVIMLRKLGLNVDYYIPNRVHEGIGINKNLLNFLKKRDAKLFITVDISINNREEILMLKNSGIDIIITDHHRQIGVLEDKEQEKELGILTINPKTSETYPNKSLSGSGVAFKLADAVYERYGVNKKILYDYMDIIMIGTVADVVPMTDENRFIIKKGLNNLKKTKIKGLKYIINYLKINPRNITTSDIGFFIAPIFNALGRIDNSKIVVNFFIQEDDFKLFSIIEEMKRANKIRRYLENEIYNELEEKIQRLERPKYIFMKSRKWHSGVIGVVCSRISIKYNIPVILISIKNGYGKASCRSIEGINIFDILKSVSDKLERFGGHDLAAGFLVSEKYLGEIEKHLRQRLARKNRENVQKTLHVDAWLNIEHLNKRKLHEINRLSPFGLDNQEPNFMDSDINFLNLTRFGINNRHFKGFVRKNNRIISVIGYNLGHKLKTNNFYKKKFKMVYTPIFKSVHSDLFIELKIKDFK
>NZ_AP019831.1|WP_146996574.1|1350013_1351300_+|trigger-factor
MAVKKLNESTYEVSAVREGEELKHLKEHVLVHFKDAKVDGFRPGHVPAKVIEKKFKKDIEGEILNHIISDEYRKAVAENELKPIADIKLEKYELNDDKVEVVFTIPVLPSFELGQYKGVEVEKEKVEITDEKVNEEIEKLRENAAKLKEVAENEEAKNDDVVNINFEGFIDGKAFDGGKAEGYDLTLGSHSFIDTFEDQIAGHKKGDEFDVNVTFPAEYHAESLKGKPALFKVKVNSIKRKEEAELNDDLAKELGFDSVEDMTAKTRENITKREEARAENEFKNKVVDAVVSATEVEVPEALVQREIDYQINRFAQQLQMQGINLNQYFQMTGQTMEAMRESSKENAEKAVKTELVLAEIAKAESIKATDEEVSKEIETLAAMYGLEKDALIADVRKNGNYERFIDETNYRLVNQKTIDLLVNEAKVK
>NZ_AP019831.1|WP_018450081.1|1351609_1352185_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MSVYSPVVIENDGRGERSYDIYSRLLKDRIIFVSGEVEDGMANAIVAQLLFLDAQDNEKDIVMYINSPGGVITAGLAIYDTMRHIKSDVSTVCVGQAASMGAVLLSAGAKGKRYSLPNSRIMIHQPLGGARGQATDIQIQAKEIERMKEITSKILSEATGKSVEEIYADTERDNFMSPEEAVNYGLIDKIL
>NZ_AP019831.1|WP_155282735.1|1352575_1353805_+|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX
MANKKKNYCSFCGREEHEVERLIQSPEEDDVFICNECIEDSAELLDSFREYDENEHNREITLLKPKEIKAKLDEYIIGQEQPKKVLSVAVYNHFKRIMHKQKNVDNDVELQKSNVLLVGPTGSGKTLLAQTLAKTLNVPLAIADATTLTEAGYVGDDVENVLLKLIKAADYDIETAEHGIIYIDEIDKIARKSENMSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIEINTKDILFIVGGAFEGLEAKVKDRVNEKRVGFGLETNNTKLDDLTLFENVLPEDLIKFGLIPELIGRLPVITALHGLDEEAMIKILTEPKNSLVKQYKKYFEMENVDLEFEKDAIVEIAQLALKRKIGARGLRSIIESVMTDLMYEIPSKENVKKVIITKEAVTDKEKVIIE
>NZ_AP019831.1|WP_155282736.1|1353872_1356239_+|endopeptidase-La
MQNKPFIATRELVVFPGVVTPIFIGRQSSLKSLEEAISRFDSKLILSAQKDANVEEPKFPEDIYETGVLVHVIQTVKMPNGNVKVLVEAKHRVLINQFPKDDNGVVYAEYEEIFSKPIDESKAEALKRRVIDEFSNYAQKTNKVLPDIIYNIKEISNIDKVFDLICTNLMIAVETKQELLEILDVEARAYKILSILEREIEIFMLEREIENRVKEQMAEVQKNYYLREKIKVMREEMGEGTDSDEELEELDQRVRDAKIPQELKDKLVKELSRMKKMPDFSAESSVIRTYLETVLELPWEVSTNDEIDIEKAEKILNEDHYGLEEVKERILEFLAIKKLNKTLKGSIICLVGPPGVGKTSLAHSVARSMNRKFTRISLGGVRDEAEIRGHRRTYVGAMPGRIINSLKQVGVNNPVMLFDEIDKMASDFRGDPASAMLEVLDPAQNNSFEDHYIDHTFDLSNVFFICTANDLGGIPGPLRDRMEIISIESYTEFEKLNIAKKYLIPQTQEENGLKDYKISFSDKAVMKIINEYTREAGVRNLRREISKLFRKIAKEILVSKSESKKISVSEAKIKKYLGNAKFRVDKVKEKEGKIGVVNGLAWTAVGGTTLEVQAVKMEGKGVLQLTGKLGDVMQESARVAYSYVRHIKNELGIKEKFNETTDVHLHFPEGAVPKDGPSAGITITTAIISVLTDKEVRQDVAMTGEITITGEVLAVGGIKEKVIGAHRVGIRDVVLPYDNKVDTEELPKEIADQMKFYFAKTYDDVKKIVFVEKEAKKSKAVKKVAEKK

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Crispr_ID: NZ_AP019831_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019831_4

1632832-1633314

Unclear

NA:I-B

Consensus_repeat	Method
GTTTCAATCCTTATTTTAATGGATATACTACTTTTAC	CRISPRCasFinder
TTTTAATGGATATACTACTTTTAC	CRT
GTAAAAGTAGTATATCCATTAAAATAAGGATTGAAAC	PILER-CR

6 spacers

csx1,csx20

The CRISPR arrays of NZ_AP019831_4

>merge|NZ_AP019831|4|1632832-1633314|CRISPRCasFinder,CRT,PILER-CR
ATTGCTTGCCTTATTTTAATGGATATACTACTTTTACGTTATTACTGGTATAGGTAATATGTTAGGATATGGGTTGTTTCAATCCTTGTTTTAATGGATATACTACTTTTACTACAAGAAAATGGCATAAAAAGATCAATTTTCATACGTTTCAATCCTTGTTTTAATGGATATACTACTTTTACTTCGGTTGTGTTGGAAGCCATTATCTTTTTTAGGTTGTTTCAATCCTTGTTTTAATGGATATACTACTTTTACTGTCGAAGAAAAAGTGTTAGAGATAAACCATACATTTGTTTCAATCCTTATTTTAATGGATATACTACTTTTACCTTTGTTGAATTCAAAGCATCCTTAAGGGTATATTACAAGTTTCAATCCTTATTTTAATGGATATACTACTTTTACTACAGAGTTACTAAGAATATCACAAGATTTGCGATGTCGTTTCAATCCTTATTTTAATGGATATACTACTTTTAC

>NZ_AP019831|4|4|1632832-1633314|CRISPRCasFinder
ATTGCTTGCCTTATTTTAATGGATATACTACTTTTAC	GTTATTACTGGTATAGGTAATATGTTAGGATATGGGTT
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC	TACAAGAAAATGGCATAAAAAGATCAATTTTCATAC
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC	TTCGGTTGTGTTGGAAGCCATTATCTTTTTTAGGTT
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC	TGTCGAAGAAAAAGTGTTAGAGATAAACCATACATTT
GTTTCAATCCTTATTTTAATGGATATACTACTTTTAC	CTTTGTTGAATTCAAAGCATCCTTAAGGGTATATTACAA
GTTTCAATCCTTATTTTAATGGATATACTACTTTTAC	TACAGAGTTACTAAGAATATCACAAGATTTGCGATGTC
GTTTCAATCCTTATTTTAATGGATATACTACTTTTAC

>NZ_AP019831|4|4|1632845-1633314|CRT
TTTTAATGGATATACTACTTTTAC	GTTATTACTGGTATAGGTAATATGTTAGGATATGGGTTGTTTCAATCCTTG
TTTTAATGGATATACTACTTTTAC	TACAAGAAAATGGCATAAAAAGATCAATTTTCATACGTTTCAATCCTTG
TTTTAATGGATATACTACTTTTAC	TTCGGTTGTGTTGGAAGCCATTATCTTTTTTAGGTTGTTTCAATCCTTG
TTTTAATGGATATACTACTTTTAC	TGTCGAAGAAAAAGTGTTAGAGATAAACCATACATTTGTTTCAATCCTTA
TTTTAATGGATATACTACTTTTAC	CTTTGTTGAATTCAAAGCATCCTTAAGGGTATATTACAAGTTTCAATCCTTA
TTTTAATGGATATACTACTTTTAC	TACAGAGTTACTAAGAATATCACAAGATTTGCGATGTCGTTTCAATCCTTA
TTTTAATGGATATACTACTTTTAC

>NZ_AP019831|4|4|1632907-1633314|PILER-CR
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC	TACAAGAAAATGGCATAAAAAGATCAATTTTCATAC
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC	TTCGGTTGTGTTGGAAGCCATTATCTTTTTTAGGTT
GTTTCAATCCTTGTTTTAATGGATATACTACTTTTAC	TGTCGAAGAAAAAGTGTTAGAGATAAACCATACATTT
GTTTCAATCCTTATTTTAATGGATATACTACTTTTAC	CTTTGTTGAATTCAAAGCATCCTTAAGGGTATATTACAA
GTTTCAATCCTTATTTTAATGGATATACTACTTTTAC	TACAGAGTTACTAAGAATATCACAAGATTTGCGATGTC
GTTTCAATCCTTATTTTAATGGATATACTACTTTTAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019831.1\|WP_155283262.1\|1642141_1645651_+\|methionine-synthase	unknown	unknown	gnl\|CDD\|273959
NZ_AP019831.1\|WP_026749258.1\|1629437_1629668_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223014
NZ_AP019831.1\|WP_155282857.1\|1625024_1625408_-\|hypothetical-protein	csx20	xls002255_csx20_CAS-I:CAS-III	unknown
NZ_AP019831.1\|WP_026749267.1\|1640987_1641359_-\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	unknown	unknown	gnl\|CDD\|179603
NZ_AP019831.1\|WP_021770172.1\|1634707_1635004_-\|type-II-toxin-antitoxin-system-YafQ-family-toxin	unknown	unknown	gnl\|CDD\|379750
NZ_AP019831.1\|WP_026749259.1\|1629942_1630635_-\|50S-ribosome-binding-GTPase	unknown	unknown	gnl\|CDD\|226124
NZ_AP019831.1\|WP_026749263.1\|1634993_1635284_-\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	unknown	unknown	gnl\|CDD\|274102
NZ_AP019831.1\|WP_026749265.1\|1636493_1638206_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_026749261.1\|1632409_1632694_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_026749264.1\|1635358_1636300_-\|Abi-family-protein	unknown	unknown	gnl\|CDD\|377910
NZ_AP019831.1\|WP_155282862.1\|1645703_1646243_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_172619099.1\|1627519_1628869_-\|TIGR02221-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	gnl\|CDD\|274040
NZ_AP019831.1\|WP_026749268.1\|1641535_1641775_-\|thiol-reductase-thioredoxin	unknown	unknown	gnl\|CDD\|200072
NZ_AP019831.1\|WP_036095732.1\|1633621_1634629_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|275027
NZ_AP019831.1\|WP_051354461.1\|1631088_1631931_-\|50S-ribosome-binding-GTPase	unknown	unknown	gnl\|CDD\|226124
NZ_AP019831.1\|WP_036095739.1\|1630790_1631087_-\|4Fe-4S-cluster-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|131546
NZ_AP019831.1\|WP_155282861.1\|1638193_1640293_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|236069
NZ_AP019831.1\|WP_146996967.1\|1629046_1629268_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_155282859.1\|1632134_1632296_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_155282858.1\|1625428_1627330_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_AP019831.1\|WP_155283262.1\|1642141_1645651_+\|methionine-synthase	gnl\|CDD\|273959	TIGR02082, Methionine_synthase, 5-methyltetrahydrofolate--homocysteine methyltransferase. This family represents 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13), one of at least three different enzymes able to convert homocysteine to methionine by transferring a methyl group on to the sulfur atom. It is also called the vitamin B12(or cobalamine)-dependent methionine synthase. Other methionine synthases include 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (MetE, EC 2.1.1.14, the cobalamin-independent methionine synthase) and betaine-homocysteine methyltransferase. [Amino acid biosynthesis, Aspartate family].	0
NZ_AP019831.1\|WP_026749258.1\|1629437_1629668_-\|hypothetical-protein	gnl\|CDD\|223014	PHA03231, PHA03231, glycoprotein BALF4; Provisional.	7.2683e-08
NZ_AP019831.1\|WP_026749263.1\|1634993_1635284_-\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	gnl\|CDD\|274102	TIGR02384, Putative_antitoxin_RelB, addiction module antitoxin, RelB/DinJ family. Plasmids may be maintained stably in bacterial populations through the action of addiction modules, in which a toxin and antidote are encoded in a cassette on the plasmid. In any daughter cell that lacks the plasmid, the toxin persists and is lethal after the antidote protein is depleted. Toxin/antitoxin pairs are also found on main chromosomes, and likely represent selfish DNA. Sequences in the seed for this alignment all were found adjacent to toxin genes. The resulting model appears to describe a narrower set of proteins than pfam04221, although many in the scope of this model are not obviously paired with toxin proteins. Several toxin/antitoxin pairs may occur in a single species. [Cellular processes, Toxin production and resistance, Mobile and extrachromosomal element functions, Other].	3.06592e-19
NZ_AP019831.1\|WP_021770172.1\|1634707_1635004_-\|type-II-toxin-antitoxin-system-YafQ-family-toxin	gnl\|CDD\|379750	pfam15738, YafQ_toxin, Bacterial toxin of type II toxin-antitoxin system, YafQ. YafQ is a family of bacterial toxin ribonucleases of type II toxin-antitoxin systems. The E.coli gene is expressed from the dinB operon. The cognate antitoxin for the E. coli protein is DinJ, in family RelB_antitoxin, pfam02604.	1.22514e-34
NZ_AP019831.1\|WP_026749259.1\|1629942_1630635_-\|50S-ribosome-binding-GTPase	gnl\|CDD\|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	1.59775e-46
NZ_AP019831.1\|WP_036095732.1\|1633621_1634629_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	gnl\|CDD\|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	0
NZ_AP019831.1\|WP_036095739.1\|1630790_1631087_-\|4Fe-4S-cluster-binding-domain-containing-protein	gnl\|CDD\|131546	TIGR02493, PFLA, pyruvate formate-lyase 1-activating enzyme. An iron-sulfur protein with a radical-SAM domain (pfam04055). A single glycine residue in EC 2.3.1.54, formate C-acetyltransferase (formate-pyruvate lyase), is oxidized to the corresponding radical by transfer of H from its CH2 to AdoMet with concomitant cleavage of the latter. The reaction requires Fe2+. The first stage is reduction of the AdoMet to give methionine and the 5'-deoxyadenosin-5-yl radical, which then abstracts a hydrogen radical from the glycine residue. [Energy metabolism, Anaerobic, Protein fate, Protein modification and repair].	4.0521e-21
NZ_AP019831.1\|WP_172619099.1\|1627519_1628869_-\|TIGR02221-family-CRISPR-associated-protein	gnl\|CDD\|274040	TIGR02221, CRISPR-associated_protein_Csx1_2, CRISPR-associated protein, TM1812 family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1812 of Thermotoga maritima, is found also in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, a large plasmid of Synechocystis sp. PCC 6803, and Fibrobacter succinogenes S85.	2.64385e-30
NZ_AP019831.1\|WP_026749267.1\|1640987_1641359_-\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	gnl\|CDD\|179603	PRK03600, nrdI, class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI.	6.23322e-36
NZ_AP019831.1\|WP_051354461.1\|1631088_1631931_-\|50S-ribosome-binding-GTPase	gnl\|CDD\|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	6.11271e-58
NZ_AP019831.1\|WP_026749264.1\|1635358_1636300_-\|Abi-family-protein	gnl\|CDD\|377910	pfam07751, Abi_2, Abi-like protein. This family, found in various bacterial species, contains sequences that are similar to the Abi group of proteins, which are involved in bacteriophage resistance mediated by abortive infection in Lactococcus species. The proteins are thought to have helix-turn-helix motifs, found in many DNA-binding proteins, allowing them to perform their function.	1.97702e-33
NZ_AP019831.1\|WP_155282861.1\|1638193_1640293_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|236069	PRK07632, PRK07632, ribonucleotide-diphosphate reductase subunit alpha; Validated.	0
NZ_AP019831.1\|WP_026749268.1\|1641535_1641775_-\|thiol-reductase-thioredoxin	gnl\|CDD\|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	5.87994e-14

>NZ_AP019831.1|WP_026749261.1|1632409_1632694_-|hypothetical-protein
MEDKAEIQEIISKIPENLQKLREIFKREYTNKILKSKNLQLQSTYTYLEKLTEEERFVEIGRIGSNGIYDFLFKVLNAQKSGENKNILITVIWL
>NZ_AP019831.1|WP_155282859.1|1632134_1632296_-|hypothetical-protein
MKKNKKIDSEIYLAKITREQFEKDFFRMFDYVRNVLETDIEEIDLESDLYWEG
>NZ_AP019831.1|WP_051354461.1|1631088_1631931_-|50S-ribosome-binding-GTPase
MKQNLLKDIENIIMGQKMDEKVREKLLGNLLKLKKQKINLMVTGATGCGKSSTINALFGMEVARIGTSADTETMEIEKYELDNLVIWDTPGLGDGKEIDNKHSKKMIDKLYEKDENGNLLIDLVLVILDSGSRDLGTAYELINNVIIPNLGENKKNRILVAINQADVAMKGKYWNEQENRPESILKEFLNNKVISVKRRIKEATGIEVKPIYYSAGYKEEGELQQKPYNLSKLLYYILQYTPEEKRVIYAQNLNKEEVMWKDSDDLKDYRKGILESVLEV
>NZ_AP019831.1|WP_036095739.1|1630790_1631087_-|4Fe-4S-cluster-binding-domain-containing-protein
MKVKIASIQRNRYEDGPGIRLTVFFQGCNVKCKGCHNSEIQDIRNGKEYEVKELCEEILSYNLPVKKITVSGGEPLMQEEALEEKENFSDKAIKNFIH
>NZ_AP019831.1|WP_026749259.1|1629942_1630635_-|50S-ribosome-binding-GTPase
MENFKHYRKTDIEKKLEKARFMPLDVMITGVTGAGKSTTLNTIFKKNVATVGNGVDPETIDLEFYSLNDVFRLWDTPGLGDGIKNDEIHKRRLVNLLYKTYSLDGNVYGWVDLAIVVLEGLNRDMGSTYTLLNEVIVPNIQADRILVVINQADMAMKGRHWNKETNKPDETLVEFLEKQASSIQDRVKEATGITIRKPVYYSAEYGYNIEKLLDFIIDNMILERRPLIKA
>NZ_AP019831.1|WP_026749258.1|1629437_1629668_-|hypothetical-protein
MWTDNDDLKDYRKGILEKFVESVAKGAMLGGAIGEILGSFAGLGGIGRIVGSVVGVGLGIAGSLVSGVVDFLGGIF
>NZ_AP019831.1|WP_146996967.1|1629046_1629268_-|hypothetical-protein
MTGIEKVVGTAVVVTAGVVAVAEGINQTVKLMNETVNTADDMFTTMGNMAEDFGNSVNDFCNEVSSFFDSLSW
>NZ_AP019831.1|WP_172619099.1|1627519_1628869_-|TIGR02221-family-CRISPR-associated-protein
MAKILIAGLGKGIKKDGKYRETNYSIEKIDKENIIYKNESFITSALEKHFEIDKTIYIGTVGSMWDNLYSYYCNKYNLKEDEDYTFELLEASSNATQDSEFSEINIKKFNDIFEGKARIILTKFGMNTNEIFENFNLIMEIGNMLNDGDEIYLDITHSFRSNAMWMFLVINYITNVLDKNVEVKMISYGMFEAKYKKEVIENGETKEIEISPVVNLKAFFDLMKWIKGANELKNYGNSYTILEMIDDKDVNKKIRTFSDSLNLNYLGTIKRNLESIKKIMDKIDSIEGPGKLIIPDIVKDFIEIFGNIEKEYEFLFKIAEWNFNQKRYAMVAININEGLREFVAGILEIKDRVSDFNDENSGIFKYFKKIRQSIEYKPNNTKGTFDKKEEKIYKIFEHTRKIRNEIAHSKGEKDTAINDVESLKNYVKDIDTIISDKGFIKYLKLKYNV
>NZ_AP019831.1|WP_155282858.1|1625428_1627330_-|hypothetical-protein
MGNTVTRNELRERVRKILVGTLLNEEEKVSDNLLDTVIKYYFPKQEKNIINGEEKWIPKKQKVIPEEEKFLERGYEDLIKKEREKISGEIDINKVKVIVSAFSLSPKNSLLEEYPFEKDLRIFDNIEKIYLFYTKETEYKFESYKNNCKFNEKIEGVEIDGRTVDETYKKLRELVLKNKINKDSTILDMTLGMKTISIAFYRIAVERQLKAVNWNEKFLSSYTMINENEFVENKNGGTPRIALSAKLSLMKEPIKESARIYSRINDSIRRGNFEAVGNLYEINGNNDMAFFYKELDTIFNADKIIKYNNFEYFYEDVGKLLDRILAKSREFSDMEISKVKKGVAYLANLVWIFSSRKKGKDSKFKLSESDFVENNFSDFRRGEENGIDLEDREEWDDSLEEIMIYLKFKYVILTNKPYFYFERIVNDMKKSQIDDNIQEKIRKYIEESEKESKKISLEKIYKLMFSKKYNFYEEIKKYDMESTLLEILENSLSYKNGILIIPIKSEYNLEAFTLKINFNEEKGLKNILKLRNFEVPIKYEPVHELLREIEIRGYDSTVTNDKIEKIFKKVENPNQSITKFKDVIKNINEVIKEKLKKEAKNENKKIEIKIPDFIEMSNAKKDYSVRISDKWKI
>NZ_AP019831.1|WP_155282857.1|1625024_1625408_-|hypothetical-protein
MEKKVLLVFSHQLTENQEKELIEGYGVKQIESLPEELQNMWSNVSIKKDYKENLEKIKKFVKENFGKKDIILIQGNWGYTYNLVKWSIENGLIPVYSYTERNVEEIKDGENVKKISYFKHVKFIEYE
>NZ_AP019831.1|WP_036095732.1|1633621_1634629_-|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta
MEKKIYEAVNWNTPENDYVEMFWEQNLKQFWIDTEYIPSKDIDSWNSLEPAMKLAYLHVLGGLTLLDTLQSHTGMPKIIDHIESLQNRSVLSYMCMMETIHAKSYSTIFTTVASTREINETFRWVQENPHLQYKANKIDGYYQKMNNPEASKREIAMALAASVYLETYLFYSGFFLPLWLAGQGEMVASCDIIKKIIADESIHGVFVGLLFQELYNSFSEEEKADMRAELKKLMYDLYENEARYTDEIYGDIGLTGDVKEYIRYNANKALMNLGFEEEFEVKNVNPIVLNGLNVETTQHDFFSKKSTNYEKALEVVHLHDDDFKFDEEVNADDLI
>NZ_AP019831.1|WP_021770172.1|1634707_1635004_-|type-II-toxin-antitoxin-system-YafQ-family-toxin
MKGKKEEYKYSIILTGKFKKHLKNLKKQKKDLKLLESIISILAKGEKLPPKNKDHKLVNNYDGARECHITPDWLLIYEIVEDKLILILLASGSHSELF
>NZ_AP019831.1|WP_026749263.1|1634993_1635284_-|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin
MATVNTSIKIDEETKKEAQKLFKDLGLSLSTAINIFLKQAIREKGIPFYINSLPENSELAQAFEEVKQIKKNPSNYKSYSSPEEMFKDVLGEDYEG
>NZ_AP019831.1|WP_026749264.1|1635358_1636300_-|Abi-family-protein
MDKPFKTFKEQVEILNGENGGKLRVKTDDETIYCLMRYNYYSIINFYKEPFLKGKDLNGNDIYKLGVHFNHLKALYDFDKSLRMLFFDVLTQLERAFKTAIAYYYSECYTNKESYLELNNYYVGVRNENIHLISHLVKKLNFLRNNKSNSIIKHYSTTKDNIPFWIVINFFTFGEMSRFYLILENRVQNKIISHFRNLYKNEYTNLPKLNNNFIKTFLRASSLFRNIAAHNERMYDFSSKNIVNINNIIGITNNKKQKLFTIYEGLKLFLSKEEYESLTKKLRELLSLLELKLKDIDINDILYKMDFPKDWHK
>NZ_AP019831.1|WP_026749265.1|1636493_1638206_-|hypothetical-protein
MFGVNKPKISHIKTIIEEKKKYNSNYFYKKRFPTTFIIIILIIPITSTGIIKYFFSNVDFFKTWISTVFLVMNLSIFWVYWCYSKRLKSKLKLGKNEIVDFYDDRVLINNRINNLFKEYIDSNYIIKLENIDELLKELENEINDEINKWKKITTITTINFSLVTPILSVVASQYFKINEKFEWINFIIFIAGYYFFGYCILVGSNFLRKKFLKEVIDIGIVELIEIKEFLLIKKNILELKINNILNEILKTDYRYENISEYLLEEDKEKILSFFRINQNESNERINGITFNIEFDYFNLHEYKNNNEESFVIFPIKLKLKKENFENNINIRIGDVYSFDFFFVLKNENGWNLINEKKFIQKYKSEYLVENKRKNPKVSSFLIVLFASIISLVVIWINKDGIRQNDVLDKGLKKYTLNNSTDKEIKIKLDTTADYNYILESYSSKKITLKAGEHSIEKNDGTKCQFTINPDSEIGIIDLKSCGVVNQQSQFKSFPKEYDYILTNLSDREISIDLYLDKEKFYKLEPNTLRKVTFKEGKYNLTKNCKLNVEFNSKGGIVTFIDSDKCEKSYY
>NZ_AP019831.1|WP_155282861.1|1638193_1640293_-|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha
MVDKRAKKWIYLNNEIMVKKGEDFQLEKDKEAVYSYFVDYVNKNTVFFHNLEEKMRYLIKNDYYIDFYEMYSHDEIKEVFKLVYDKKFRFASFMSASKFYQSYALMDDSGEKFLERYEDRVATVSLYLAQGDVEKAKEYALMLINQEYQPATPTFLNSGKKRSGELVSCFLDEMGDNLSGIGYVFDSSMKLSSIGGGVAINLSKIRARGESIKGVEGRASGVLPIMKILEDIFSYANQLGQRAGAGAVYLNVFHSDINEFLDSKKINVDEKIRIKSLSIGVIVPDKFMQLAMEDEVCYTFNPHTVFLEYGQYLDEMDMNEMYEKLVDNPNVKKKKINARELLVKISQTQKESGYPYLFFKDNANKEHALKEIGTVKFSNLCTEIMQLSEVSDINAYYEEDTIRRGISCNLGSLNIATVMENKRIKEATKAAIDSLTMVSDLTNIDIVPSIKKANDELHSVGLGAMNLHGYLAKNFIMYESKEALDFCNVFFMMVNFYSLERSMEIAKEKGETFKDFEKSEYANGNYFDKYITKEYMPQTEKIKQLFEGIYIPTKEDWANLKEQVMKHGVYNAYRMAIAPNQSTSYIMNSTASVMPVVDTIEVREYGDSTTFYPMPYLTNDNYFFYKSAYDMDQKNILKLISVIQRHVDQGISTILYTKSTDSTRDLARLYIYAHRLGLKSLYYTRTRKATIEECISCSV
>NZ_AP019831.1|WP_026749267.1|1640987_1641359_-|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI
MYIYYDSKTGNVERFIKKMQVQRPDWHFIKIEPTMTIENEGHFLTFTTKIGEIPATTDEFLQNENNSKLLKSVSSSGNRNWGQFFALAADKIQQKYGIPVLMKFELSGTSTEVENYIDYLENN
>NZ_AP019831.1|WP_026749268.1|1641535_1641775_-|thiol-reductase-thioredoxin
MKKIIKFEKNDCNPCAMVSDLLDKKGVEYERINPFDNPEIAVKYKVRSVPTVILFEENEEIKRTIGFKPEEINEIISMM
>NZ_AP019831.1|WP_155283262.1|1642141_1645651_+|methionine-synthase
MLTNQYKNSYNLLQNDLKNRILLLDGAMGTMIQQENLTADDFGGEKYEGCNDYLVLQKPEIIKNIHKRYLEAGSDIIETNSFGALDIVLKDYDLEDKVFEMNKAAAELANEAIAEYKNEHPEVTRNLYVAGALGPSNKSISVTGGVTFEELIHTYYTAVSGLLSGGVDLILFETIQDTRNLKAAYLGLKKAMEENYTVPLMLSFTIESTGTTLAGQTADAFYYAVNHMNPFSVGLNCATGPEFMTQFLKTLNNISNTYISVYPNAGLPNEDGEYEETPDTLSAKIEPFFQNNYLNIVGGCCGTTPEHIQKIKEKSVNYSPRVIDENKDFNDVSGLIALETPKDRPIYVGERTNVIGSRIFKNLIVSEKFDEATEVARLQIKGRADVIDICLANPDRDEIADMKAFLDKVAKFAKVPLMIDSTDINVVKEGLTYLQGKGIINSINLEDGEKKFADMAKVIKDFGASVVVGLIDEEGMAVSVEKKLKVARRSYELLTKKYKIDERDIIFDTLVFPVATGDQKYIGSATATIEAIRQIKDEMPNVKTILGVSNISFGLPIAGREVLNTYYMQKAYEAGLDYAIVNTEKVIPMSEISDEEKELSENILFHTDDENVSKFANFYREKKAVQKVVDTSNLTTEEKVSNLVVEGSKKDLTTHLDELLQKYSPIDIINGPLMTGMDEVGKLFNNNDLIVAEVLQSAEVMKASVSHLEQFMEKDESSIKGKVIMATVKGDVHDIGKNLVGIIIGNNGYEVIDLGINTPAEKIREAIIEHKADFLGLSGLLVKSATEMVNTMEVLHEADIDIPIFVGGAALTEKFTVNKIEPAYKNNIVIYSRDAMTALADLNKMIDEKKFEEFKEYLQKRRDLVTIKDAKKLEQLKVKPTVSDIKDADGTFDFSKVELPKYNFEKIYKPETLNKQIITNIKAKDVFPFVNLQMLIGKHLGMKWIVNNLIEKQDPRTIKLYNEILDIIENGDEYFDIKAIYKFFPVRRKVGERKDDFKIEVLSDDLSTVLETFDFPRQKYGQYLSLNDYVNPDRIDYIGFFVATAGEKSRLVSNELKEKGEFYRGHIVNSIGLELAEATSEYIHKMMRQDVGIIDKDITLNEILNAQYQGNRYSFGYPACPDLSDQRKLFNLLKPERYGISLTEEFMMYPEATVSAIVFSQPFCKYFNM
>NZ_AP019831.1|WP_155282862.1|1645703_1646243_+|hypothetical-protein
MYQIIKMILLSSVFIDYIDIQKLDKSGFTTHIIEIMLVLSLINSIVNLYDEKKFLIIEFLIIILFHLAGNKIILENFSFFWQSIKLIGVYILHLLITTDVGMDDNNINPFSKAEWTIVLVTVLIFLLLMLIFKIEINSLSILSLYCITLFELKGIFRNLTEYIETQKKIEKENKDKWQK

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Crispr_ID: NZ_AP019831_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019831_5

1717139-1717245

Orphan

Consensus_repeat	Method
GGATAACAGTCCCTTCCCCTTTGCTTCAAGTTTAAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP019831_5

>merge|NZ_AP019831|5|1717139-1717245|CRISPRCasFinder
GGATAACAGTCCCTTCCCCTTTGCTTCAAGTTTAATTAGCGGCAGATCCAATTGAAGGTGGCATTTCAACTGGATAACAGTCCCTTCCCCTTTGCTTCAAGTTTAAT

>NZ_AP019831|5|5|1717139-1717245|CRISPRCasFinder
GGATAACAGTCCCTTCCCCTTTGCTTCAAGTTTAAT	TAGCGGCAGATCCAATTGAAGGTGGCATTTCAACT
GGATAACAGTCCCTTCCCCTTTGCTTCAAGTTTAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019831.1\|WP_051354462.1\|1704321_1705464_-\|YARHG-domain-containing-protein	unknown	unknown	gnl\|CDD\|372555
NZ_AP019831.1\|WP_155282883.1\|1707221_1709438_+\|cadmium-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319847
NZ_AP019831.1\|WP_146997032.1\|1722881_1723688_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_026747932.1\|1723766_1724072_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_155282894.1\|1720864_1721542_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_155282889.1\|1713546_1714722_-\|YARHG-domain-containing-protein	unknown	unknown	gnl\|CDD\|372555
NZ_AP019831.1\|WP_173020662.1\|1726195_1726744_-\|DUF1311-domain-containing-protein	unknown	unknown	gnl\|CDD\|377758
NZ_AP019831.1\|WP_155282886.1\|1711699_1712854_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|276809
NZ_AP019831.1\|WP_146997033.1\|1724827_1725106_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_155282885.1\|1711175_1711691_-\|adenylate-kinase	unknown	unknown	gnl\|CDD\|379324
NZ_AP019831.1\|WP_155282892.1\|1718984_1720001_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_155282893.1\|1720031_1720823_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_146997031.1\|1721626_1722856_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|237355
NZ_AP019831.1\|WP_146997035.1\|1725655_1726129_-\|SH3-domain-containing-protein	unknown	unknown	gnl\|CDD\|377965
NZ_AP019831.1\|WP_146997034.1\|1725220_1725622_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_155282884.1\|1709668_1710934_-\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|234856
NZ_AP019831.1\|WP_155282890.1\|1715195_1716728_-\|DKNYY-domain-containing-protein	unknown	unknown	gnl\|CDD\|372659
NZ_AP019831.1\|WP_155282882.1\|1705571_1706744_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225405
NZ_AP019831.1\|WP_155282887.1\|1712965_1713241_-\|Txe/YoeB-family-addiction-module-toxin	unknown	unknown	gnl\|CDD\|131171
NZ_AP019831.1\|WP_155282888.1\|1713234_1713474_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl\|CDD\|376852

Protein	Function_ID	Function_description	E-value
NZ_AP019831.1\|WP_051354462.1\|1704321_1705464_-\|YARHG-domain-containing-protein	gnl\|CDD\|372555	pfam13308, YARHG, YARHG domain. This presumed extracellular domain is about 70 amino acids in length. It is named YARHG after a conserved motif in the sequence. This domain is associated with peptidases and bacterial kinase proteins. Its molecular function is unknown.	2.9806e-13
NZ_AP019831.1\|WP_155282883.1\|1707221_1709438_+\|cadmium-translocating-P-type-ATPase	gnl\|CDD\|319847	cd07548, P-type_ATPase-Cd_Zn_Co_like, P-type heavy metal-transporting ATPase, similar to Bacillus subtilis CadA which appears to transport cadmium, zinc and cobalt but not copper out of the cell. Bacillus subtilis CadA/YvgW appears to transport cadmium, zinc and cobalt but not copper, out of the cell. Functions in metal ion resistance and cellular metal ion homeostasis. CadA/YvgW is also important for sporulation in B. subtilis, the significant specific expression of the cadA/yvgW gene during the late stage of sporulation, is controlled by forespore-specific sigma factor, sigma G, and mother cell-specific sigma factor, sigma E. This subfamily also includes Helicobacter pylori CadA an essential resistance pump with ion specificity towards Cd(2+), Zn(2+) and Co(2+), and Zn-transporting ATPase, ZiaA(N) in Synechocystis PCC 6803. Transcription of ziaA is induced by Zn under the control of the Zn responsive repressor ZiaR. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_AP019831.1\|WP_155282889.1\|1713546_1714722_-\|YARHG-domain-containing-protein	gnl\|CDD\|372555	pfam13308, YARHG, YARHG domain. This presumed extracellular domain is about 70 amino acids in length. It is named YARHG after a conserved motif in the sequence. This domain is associated with peptidases and bacterial kinase proteins. Its molecular function is unknown.	8.34217e-17
NZ_AP019831.1\|WP_155282886.1\|1711699_1712854_-\|hypothetical-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	2.48478e-07
NZ_AP019831.1\|WP_155282885.1\|1711175_1711691_-\|adenylate-kinase	gnl\|CDD\|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	0.000105794
NZ_AP019831.1\|WP_173020662.1\|1726195_1726744_-\|DUF1311-domain-containing-protein	gnl\|CDD\|377758	pfam07007, LprI, Lysozyme inhibitor LprI. This family consists of several bacterial proteins of around 120 residues in length. Members of this family contain four highly conserved cysteine residues. Family members include lipoprotein LprI from Mycobacterium, which binds to and inhibits macrophage lysozyme, which may aid bacterial survival.	7.53549e-11
NZ_AP019831.1\|WP_146997031.1\|1721626_1722856_-\|AAA-family-ATPase	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NZ_AP019831.1\|WP_146997035.1\|1725655_1726129_-\|SH3-domain-containing-protein	gnl\|CDD\|377965	pfam08239, SH3_3, Bacterial SH3 domain.	6.23615e-05
NZ_AP019831.1\|WP_155282884.1\|1709668_1710934_-\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|234856	PRK00885, PRK00885, phosphoribosylamine--glycine ligase; Provisional.	0
NZ_AP019831.1\|WP_155282890.1\|1715195_1716728_-\|DKNYY-domain-containing-protein	gnl\|CDD\|372659	pfam13644, DKNYY, DKNYY family. This family represents a group of proteins found enriched in fusobacteria. These proteins contain many repeats of a DKNXXYY motif. The repeats are spaced at about 35 amino acid residues intervals. These proteins are likely to be associated with the membrane. The specific function of these proteins is unknown.	1.02138e-18
NZ_AP019831.1\|WP_155282882.1\|1705571_1706744_-\|hypothetical-protein	gnl\|CDD\|225405	COG2849, COG2849, Uncharacterized protein conserved in bacteria [Function unknown].	1.24569e-06
NZ_AP019831.1\|WP_155282887.1\|1712965_1713241_-\|Txe/YoeB-family-addiction-module-toxin	gnl\|CDD\|131171	TIGR02116, Hypothetical_protein_Rv3358/MT3466/Mb3393., toxin-antitoxin system, toxin component, Txe/YoeB family. The Axe-Txe pair in Enterococcus faecium and the homologous YefM-YoeB pair in Escherichia coli have been shown to act as an antitoxin-toxin pair. This model describes the toxin component. Nearly every example found is next to an identifiable antitoxin, as indicated by match to models TIGR01552 and/or pfam02604. [Cellular processes, Toxin production and resistance, Mobile and extrachromosomal element functions, Other].	9.59408e-18
NZ_AP019831.1\|WP_155282888.1\|1713234_1713474_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl\|CDD\|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	2.49204e-05

>NZ_AP019831.1|WP_155282890.1|1715195_1716728_-|DKNYY-domain-containing-protein
MKKNIFKVLVLAILLGNIGFGEYIKKNGRVYYRQDESYSDLEEVKKSFREIEKEGNFYRVLDIQYFPADMDTFQDINGEYGKDKDRVYFEKNEIYEADLASFVIVKGNISKDKNFVYNMGDRIYLEDDDEFIIENENLRKKIDSITLKVFNSPDKNSVRYIGDKNGIYYVLNDAQRIKGADFKTFEELGYSYAKDKNSIYFENRKIKGADISSFEVLNDGYAKDKNSFYLEGEKVKGVNKSTSKEPSENMAQKGRTVIGLLEIDDNNVYNIDEPLNISPKNFSLIGERNDYVKNDKGVYFIDIYNVSKPTTVEKLPVNPDKFRVIKKNYLKDDKIVYYNSNHGNMKVEDADAASFQELTENYGKDKNYIYYGEQKIENSDSNSAKAITDIILKDKHNVYYIGQKLEGISDAETFEAISDVKGLNGFYAKDKHNVYFISDSDFSEKVKKLEKLNVNKTKVLNEYYVKDDKKVYCLGERINGADARSFKVKNEYSSQGEDRNHKYEYCKITE
>NZ_AP019831.1|WP_155282889.1|1713546_1714722_-|YARHG-domain-containing-protein
MKKIRVFLLFCLMFLIGLNLLANDWEFGSEGGHIVPMNMSDIAIKSEKLHFKLEKVKSEYGLESEMVVTVRFVFDSPEAGEKYIGFITPEGGNDEWDEVNHFKNFKTVVNGKNVNTVSYRLTDFVPKDIKKLEEVKKYFKEYDEEKAKEEADYYKRSYVYYFKSNFKKGENVVEHSYRYDGSGGVGVNDFNYVWTTISKWKNQKVDDFEVIVEPGSALIAIPEIKMKNGKNIEWKLVGEGNIDYGYKDYYDRDGQYRMLYAKLKNGYLHFKTKNFEPKDEFSLVEIAYINGNHAFPEKTEKGFKYRDDLTQAAYRAEYLPADEFKELTNEDLKIMRNYPYAMAGYDFSDKKLKDYFSKFLWYIPTTKDVKLDKYDYDVVKAVDKIIDSRKK
>NZ_AP019831.1|WP_155282888.1|1713234_1713474_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MTNINATNLRKNLFFYLESAIDYNEIINVNTKKGNAIIISEAEYNGLLETLYLLSDPTMKEKIEAAKNATDEDYEAFEW
>NZ_AP019831.1|WP_155282887.1|1712965_1713241_-|Txe/YoeB-family-addiction-module-toxin
MVEEYKIYILKKANKDKEKIKQFSALKNNVEKLINLIKKNPFQTPPSYEVLTKDLKGYYSRKINKQHRLVYEVIEEEKRINIISMWTRYEI
>NZ_AP019831.1|WP_155282886.1|1711699_1712854_-|hypothetical-protein
MDIEVKLNEGMKKYIYKIWEKMGNEDRTEYDAALENYRKYLLKETTKNPEDVSVVCQLVGVCYLSRKCDGIEILETFLKRNFDILTEDEKFRIYVDLAYLCEDMGCMEEEAINYLEKAIKINSNNADIYYRLAGICFYAKIYQKSLENIEIVCKMSDEAKYSYGYALILIQNKEYKKAEKILDNLLMEDSNNIKYHFYRVLCKIYLGNKDTENIEKLLEKIKEFEMLEKTDYEKYLNWLTYEGFDTIDNGDIKDLYYLCGNYEKYCKYAENVNFNLEANYMAPYLYSLKQLNKFEKIDKILKEAEKEIFQNIEEIKTDEEYQKDTTEEELLEMIEDEKQKLKNINLVSRKILNTDFKPKVEIFMFFENECWLLDCPQHLIIDEN
>NZ_AP019831.1|WP_155282885.1|1711175_1711691_-|adenylate-kinase
MIILIMGASHTGKTKLAQKLLEKYKYPYLSIDHLKMGLIRSGHTELTAMSSDEELTDLLWPIISEMIKTAIENKQNLIVEGCYISFDWKKDFEKEYLENIRCICLVMSKNYINKHFDDIKKHANVVESRIDDSYCTLESVLKDNDKVLKLCQIHNIDYTLIDDEYQFDIEL
>NZ_AP019831.1|WP_155282884.1|1709668_1710934_-|phosphoribosylamine--glycine-ligase
MKILIVGAGGREHAIAWKLSQNEKVEKIFIAPGNACVEMLPNAESVNLGSIDEYISFAKDNNVELTVVGSEELLVQGIVDEFHKNGLKIFGPDKKAAILEGSKAYSKDFMKRYGIKTAVYEIFDNSEKAKEFLNNWKDFPVVIKASGLAAGKGVIIAQNLNEAIKAVEDIMVDEKFGNAGSQVVIEEFLDGVEASILSFTDSKIIVPLLSAKDHKKIGEDETGLNTGGMGVISPNPFVTDEIFEKFKSDIMEPTLKGMQAEGMDFAGVIFFGLMITKKGVYLLEYNMRMGDPETQAVLPLLENDLLELIEKSFDKKLSEVKVNWKSLHSCCVVAAAGGYPESYKKGDEITGVLNFNETEDKKVFICGAKVENGKLLTNGGRVLNAVALGNTLEEAQKKAYKLLNSINFKGMYFRKDIGGRF
>NZ_AP019831.1|WP_155282883.1|1707221_1709438_+|cadmium-translocating-P-type-ATPase
MKTNECTLFIEGVDCPNCAAKIERKLNTLQRIKAATVDFLGKRVIVESENFSQDELAEFIQAEVNKIENGVKISTKKLHAHSHSHSHAHAHSHDHSHSHAHGEEDTDKIKKKLLIGGILFVLGIFIPKPLFIPKFAVFLVSYLIIGGDVLLSALKNILKGQVFDENFLMAIATVGAFAIGEYPEGVAVMLFYQLGELFQGIAVNNSRKSIIALMDIRPDYANLKTDDGIKKVNPEEIKVADIIVVKPGEKVALDGKIINGSSTFDTSALTGESLPREAKTGDSVLSGFINKTGLIEIEVTKVFSESTVSKILNLVENASSKKSKTENFITKFAKYYTPAVVITALIMAIFPPLLISGATFTDWIYRALIFLVVSCPCALIISIPLGFFGGIGGASKHGILVKGANYLEALNDVESIVMDKTGTLTKGVFKVTEINVENNVKINDFENNKTDLTQSLLLKYAAHIEKFSTHPIAQSIVSEYENSATKTDESIVKDFEEISGFGIKANINNHQVLAGNSKLMNSENIEFTEKENLGTVIYIAFDGQYIGNILISDEIKADSPKAIKGMKANRIKEIVMLTGDNKAIGKNIAQKLGIDKVFAELLPNEKVEKLEEIYKTKSEKGKVVFVGDGINDAPVLARADIGIAMGGVGSDAAIEAADVVIMNDEPSKIVTAMKIAKKTKTIVWQNITLAFAVKLIVLLLGLFGDATMWEAVFADVGVALLAVLNATRVLKYKVNENY
>NZ_AP019831.1|WP_155282882.1|1705571_1706744_-|hypothetical-protein
MRCYFFEKNSKVQNYLRKVMILVAALMISTISFGVKLGTVKGLSRLSNYNKLKDIDVNAITNLQISKNGEVINPSTNFAGVGIANHKGKIIGVYFYKNGKQNGKSYVYYDNGQVYLENEIKNEKYEGEGKSYYDDGQLQSARIYKDDIILLLKKYKHDGSLDFTYTQTSGYNGIMTYHKREGNIETVEKVEASYREKNEGRVLVVSIIFTKNGAFQVYNNKGRLIRDGVYRNDEIVTSNKVDKFSGFILQDGTYKVNVENRDYFFQTLKDFKMKGLTEEFYKGTVELFGSKPYCSSIGMLFVHYRIFKDDPVTDIIGSYLLKISRDAKKTAKKYTELNDNDFLVKYYKTNCKVPSESKLSFVENLEVSKEFESNRNPKEIREFFKNPVIK
>NZ_AP019831.1|WP_051354462.1|1704321_1705464_-|YARHG-domain-containing-protein
MKKLGVAILMLAFIISCGNKKDETGNGKNSATASTVKQEKIQNPQGPTVALNQADFKIENDFIYYQGNIFNGKVIFDNNVKSGYIYVSNGKIEGEAEINYKLSGIKRTEVYKQGNLVSFSVTENGITTEIGLTADSNSNSYMSKKTPATVSTKYGKNSYFINLENATGRMEINGKIFDNLNADVEEENVQSISSIISENGGNYKVKYIYDITQGKILEKKYKMDSKSDKSEVLSEIRELADINMEFSNGMRMFGELLDASVAASQMPQNAAVTPQPAPAPVNTATQPQPAPTGQDSDLELLDRVYDEVMHKNNTAILNTFSKEKIGYIRNTMFAKKGYKFKNPKYASYFSQKSWYRGIYDSDEILSPEEKRFVLILKEKE
>NZ_AP019831.1|WP_155282892.1|1718984_1720001_+|hypothetical-protein
MGFINPFQIYSKGENTITNNILLLLSNLYRINPKIYELFINSVLPENINYEVIPVFTQQKSQKEGGIIDGHIQTKATKIIIETKITGLDNTKKLINYCKNENLTETNILIHISDSTFDETTIKSINQKIGIYNFNFVSITFSELISSLQEIADEYPFNEELYRLSKDFYYYCSSMGLIKNVFRIVPCNKSFELNEKYHLYFQPESRGYSNHQFTGIYTAKEVKYIGKVNKVFLAELTKEGKLITKKISGNGEITSEEENRIINTIREFPEIYIYGDISKGHIFFLFDDNDFCPTKFKKTSKYGLLGSRLFDLKVNLEIENVERLSTLEIAEKLNDITW
>NZ_AP019831.1|WP_155282893.1|1720031_1720823_+|hypothetical-protein
MKKLLLILSLFVINIVGLAYEKCNPKMIYDINLNTLNGSYLGQNKKDGTIMIKLGKNANKVQAIHFDENRILNNCILDPKITEFHIEHGLFINAMYDEMLDGVYNNDQDIKIDYDSCLEKNHQFCKISKDADINGNPVGISFNQEVQDIEIHGNIVDVEKRNDYKKVIIGEGYEEDNIAVCASKSISEENCKKEKFIVKSPNGYVNLTRKAYDNSTVRDKLKNGTIVVIDPIDINPFDVEGVYVEVLGQRKFGYINWKYLEKK
>NZ_AP019831.1|WP_155282894.1|1720864_1721542_+|hypothetical-protein
MENNNIENKNLVKILIGIIIALVLVIGFIIIGGGIYQFVSMKNKINEMEKVQKEQEKKQLENQMMASVQTQAKEDNKKSETKTNETKTETKEVDPYERRFTASDMNDTLVEIKGVRDGNKVLVRVLEGKNKNKKGYINLKGFKNISSSSLRKLIGSTWAATGVNNGVEMEYGLILHRPGSDIYSFNLNKVLIDYKLSGHDSAVRYDCERDTARNFVQNYDPSACY
>NZ_AP019831.1|WP_146997031.1|1721626_1722856_-|AAA-family-ATPase
MNLFDEVYEDKKPLAFRYRPKSLDDFYGQKRLVGENGILRKIIERGNFMNAIFWGAPGTGKTTLAEIIADKMNYHYEYLNAIKASVTDIKNISDKAHSSFHTNGQQTLLFLDEIHRFNKLQQDSLLEDLENGNIILIGATTENPYYNLNNALLSRCMAFEFKKLSEDDLLKILKNINEKENFGISDDILGYISEIIEGDARQAINILELITNVGVEFTLEEVKEILNMKKSYHKTEDKYNTISAMIKSIRGSDPDAAVYWMAKMLSGGEDILYIARRLVILASEDIGLANPQALPVAVAGLNAIKEIGMPEARIILSEVAIYLAISPKSNSAYNAINSALSHIENEKIQEVPVHLTKVGAKDYKYPHNYENHYVDQIYMNEKIKFYEHGENKFEKAADEWLKKIKKNQK
>NZ_AP019831.1|WP_146997032.1|1722881_1723688_-|hypothetical-protein
MENFEKKVERDFFDVFLGILKITGIFISTWIVLLVQRAIFNYYYYINVLKLNYGNENAGMIPTLVEVVFSFTVLIILTVIFIKMMKVRFGANNLIKIMLCTFAMMVIIIFLLGGGFAFSVSKNSEIMDLNYMILMFFKKGILNGIMGTELVGILLTISLFSIKVYEKNNGKSIFSIIYTAINSIILIIMYYFISIFMDIYMYQTIAGTENDYIWKFIIEIIKSTDLSKAIFNYFFYVVVLIIVIFTTILVLNVFSDNKKSELKINNTK
>NZ_AP019831.1|WP_026747932.1|1723766_1724072_-|hypothetical-protein
MLYEDKEQKYSLFANPKTGKIVKIDIKDGKYFPAEDLKIGDYLTEEKMEKYEIYYDEDDEDVWLSEVVKELAMVTELVGEYPNQKEKILWYVWFDYKEYSF
>NZ_AP019831.1|WP_146997033.1|1724827_1725106_-|hypothetical-protein
MKISKRLLMVTVISIFTGVAGNAMANGRICSGVLSNGDYSGRFRVTANGGLSYYTEYLEIENGEIRIYPTFNFQTRELAFDIRDDNVRVSCE
>NZ_AP019831.1|WP_146997034.1|1725220_1725622_-|hypothetical-protein
MRISKKLLTIIGALILVAVVAVATENNMMKKTTKKIVAEDTMKKEPLVKMEEKFNNYARYEKYEELFEYFFETFYPEMKRQNYSKLQHFIEVTFFINDQLKDENEKLYNKNVKRFKRAGLDYAYSSKHKEMKD
>NZ_AP019831.1|WP_146997035.1|1725655_1726129_-|SH3-domain-containing-protein
MRKLLLMSILLGVSSLGFSKTFFQVYLNDASLANLREKPSSSSKILAGLDMFEEGELIRKEGNWYYIKYRTESGKMLYGYIHKSQGYLMETYVVSSKDGYANIRWEPSSSAKIAGKEKNGKILEVYEEKGDWLYITYGDSPHIPVAYVHRSQVKKEK
>NZ_AP019831.1|WP_173020662.1|1726195_1726744_-|DUF1311-domain-containing-protein
MKKCRKLMLMVIFLAFCSLGFSKEVTEMSSNNKIESEKSSQNMGNNNVIQEIINSIPSSKANKRKSDYEAKLISKMKIVEKRIQDKMDNSSSSLEVKEAIGELDKKWDDELNKVYKLVMGKLPANLKTKLRNSQREWIQYRDKEAEEESRETGSVEAYGDTTTKLTKEKTIQLAKLYDSLKN

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Crispr_ID: NZ_AP019831_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019831_6

2566859-2566963

Orphan

Consensus_repeat	Method
TGGTTCTCTTTTCACATATACAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP019831_6

>merge|NZ_AP019831|6|2566859-2566963|CRISPRCasFinder
TGGTTCTCTTTTCACATATACAACTTTTTTTCTTCTTGGAACTCTTATAAAGATGTATCTTCTTCTTATTACTCTTCTTCTTGGTTCTCTTTTTACATATACAAC

>NZ_AP019831|6|6|2566859-2566963|CRISPRCasFinder
TGGTTCTCTTTTCACATATACAAC	TTTTTTTCTTCTTGGAACTCTTATAAAGATGTATCTTCTTCTTATTACTCTTCTTCT
TGGTTCTCTTTTTACATATACAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019831.1\|WP_026749441.1\|2574869_2575283_+\|adhesion-protein-FadA	unknown	unknown	gnl\|CDD\|370466
NZ_AP019831.1\|WP_155283157.1\|2556291_2557245_+\|ATPase	unknown	unknown	gnl\|CDD\|379051
NZ_AP019831.1\|WP_146997579.1\|2572907_2574218_+\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_AP019831.1\|WP_026749440.1\|2574381_2574789_+\|adhesion-protein-FadA	unknown	unknown	gnl\|CDD\|370466
NZ_AP019831.1\|WP_155283164.1\|2575612_2576503_+\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|273359
NZ_AP019831.1\|WP_051354473.1\|2571955_2572681_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_036095824.1\|2569603_2569972_+\|nucleotide-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|212143
NZ_AP019831.1\|WP_146997573.1\|2563065_2563284_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_026749444.1\|2577590_2578238_+\|C40-family-peptidase	unknown	unknown	gnl\|CDD\|236773
NZ_AP019831.1\|WP_026749429.1\|2562205_2562988_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019831.1\|WP_155283160.1\|2565092_2565770_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223836
NZ_AP019831.1\|WP_155283163.1\|2570089_2571745_+\|5'-nucleotidase-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|223808
NZ_AP019831.1\|WP_155283159.1\|2560675_2562205_+\|dynamin-family-protein	unknown	unknown	gnl\|CDD\|366045
NZ_AP019831.1\|WP_173020694.1\|2564273_2565035_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_AP019831.1\|WP_146997570.1\|2559158_2559977_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|319818
NZ_AP019831.1\|WP_155283162.1\|2567361_2569152_+\|NAD-nucleotidase	unknown	unknown	gnl\|CDD\|211667
NZ_AP019831.1\|WP_155283158.1\|2558218_2559079_-\|GyrI-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|226231
NZ_AP019831.1\|WP_026749431.1\|2563367_2564216_-\|cysteine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270412
NZ_AP019831.1\|WP_146997582.1\|2576602_2577391_+\|META-domain-containing-protein	unknown	unknown	gnl\|CDD\|377111
NZ_AP019831.1\|WP_155283161.1\|2565750_2566410_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223836

Protein	Function_ID	Function_description	E-value
NZ_AP019831.1\|WP_026749441.1\|2574869_2575283_+\|adhesion-protein-FadA	gnl\|CDD\|370466	pfam09403, FadA, Adhesion protein FadA. FadA (Fusobacterium adhesin A) is an adhesin which forms two alpha helices.	1.3321e-24
NZ_AP019831.1\|WP_155283157.1\|2556291_2557245_+\|ATPase	gnl\|CDD\|379051	pfam13177, DNA_pol3_delta2, DNA polymerase III, delta subunit. DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.	1.40342e-38
NZ_AP019831.1\|WP_146997579.1\|2572907_2574218_+\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_AP019831.1\|WP_026749440.1\|2574381_2574789_+\|adhesion-protein-FadA	gnl\|CDD\|370466	pfam09403, FadA, Adhesion protein FadA. FadA (Fusobacterium adhesin A) is an adhesin which forms two alpha helices.	5.22541e-21
NZ_AP019831.1\|WP_155283164.1\|2575612_2576503_+\|EamA-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	2.95693e-19
NZ_AP019831.1\|WP_036095824.1\|2569603_2569972_+\|nucleotide-pyrophosphohydrolase	gnl\|CDD\|212143	cd11536, NTP-PPase_iMazG, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in integron-associated MazG (iMazG) proteins. This family corresponds to the iMazG proteins representing a new subfamily of MazG NTP-PPases. iMazG is likely to act as a house-cleaning enzyme capable of removing aberrant dNTPs, preventing the incorporation of damaging non-canonical nucleotides into host-cell DNA. It can convert dNTP to dNMP and pyrophosphate by cleaving between the alpha- and beta-phosphates of its dNTP substrates, with a marked preference for dCTP and dATP. Unlike typical tandem-domain MazG proteins, iMazG contains a single MazG-like domain and functions as a tetramer (a dimer of dimers) with a typical four-helical bundle. The divalent ions, such as Mg2+, are required for its pyrophosphatase activity.	1.55233e-30
NZ_AP019831.1\|WP_026749444.1\|2577590_2578238_+\|C40-family-peptidase	gnl\|CDD\|236773	PRK10838, spr, bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase.	5.84076e-34
NZ_AP019831.1\|WP_155283163.1\|2570089_2571745_+\|5'-nucleotidase-C-terminal-domain-containing-protein	gnl\|CDD\|223808	COG0737, UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism].	2.17375e-89
NZ_AP019831.1\|WP_155283160.1\|2565092_2565770_-\|ABC-transporter-permease-subunit	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	5.03167e-60
NZ_AP019831.1\|WP_155283159.1\|2560675_2562205_+\|dynamin-family-protein	gnl\|CDD\|366045	pfam00350, Dynamin_N, Dynamin family.	1.51694e-13
NZ_AP019831.1\|WP_173020694.1\|2564273_2565035_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	2.03246e-136
NZ_AP019831.1\|WP_146997570.1\|2559158_2559977_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|319818	cd07516, HAD_Pase, phosphatase, similar to Escherichia coli Cof and Thermotoga maritima TM0651; belongs to the haloacid dehalogenase-like superfamily. Escherichia coli Cof is involved in the hydrolysis of HMP-PP (4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate, an intermediate in thiamin biosynthesis), Cof also has phosphatase activity against the coenzymes pyridoxal phosphate (PLP) and FMN. Thermotoga maritima TM0651 acts as a phosphatase with a phosphorylated carbohydrate molecule as a possible substrate. Escherichia coli YbhA is also a member of this family and catalyzes the dephosphorylation of PLP, YbhA can also hydrolyze erythrose-4-phosphate and fructose-1,6-bis-phosphate. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.34443e-66
NZ_AP019831.1\|WP_155283162.1\|2567361_2569152_+\|NAD-nucleotidase	gnl\|CDD\|211667	TIGR01530, Probable_5'-nucleotidase, NAD pyrophosphatase/5'-nucleotidase NadN. This model describes NadN of Haemophilus influenzae and a small number of close homologs in pathogenic, Gram-negative bacteria. NadN is a periplasmic enzyme that cleaves NAD (nicotinamide adenine dinucleotide) to NMN (nicotinamide mononucleotide) and AMP. The NMN must be converted by a 5'-nucleotidase to nicotinamide riboside for import. NadN belongs a large family of 5'-nucleotidases and has NMN 5'-nucleotidase activity for NMN, AMP, etc. [Transport and binding proteins, Other, Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides].	0
NZ_AP019831.1\|WP_155283158.1\|2558218_2559079_-\|GyrI-like-domain-containing-protein	gnl\|CDD\|226231	COG3708, COG3708, Uncharacterized protein conserved in bacteria [Function unknown].	4.78533e-31
NZ_AP019831.1\|WP_026749431.1\|2563367_2564216_-\|cysteine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270412	cd13694, PBP2_Cysteine, Substrate binding domain of ABC cysteine transporter; the type 2 periplasmic binding protein fold. This subfamily comprises of the periplasmic-binding protein component of ABC transporter specific for cysteine and its closely related proteins. The cysteine-binding domains belong to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	6.30303e-123
NZ_AP019831.1\|WP_146997582.1\|2576602_2577391_+\|META-domain-containing-protein	gnl\|CDD\|377111	pfam03724, META, META domain. Small domain family found in proteins of of unknown function. Some are secreted and implicated in motility in bacteria. Also occurs in Leishmania spp. as an essential gene. Over-expression in L.amazonensis increases virulence. A pair of cysteine residues show correlated conservation, suggesting that they form a disulphide bond.	6.24595e-22
NZ_AP019831.1\|WP_155283161.1\|2565750_2566410_-\|ABC-transporter-permease-subunit	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	3.27988e-57

>NZ_AP019831.1|WP_155283161.1|2565750_2566410_-|ABC-transporter-permease-subunit
MDFNFIIENISKYLEAMKLTVLIGIFGIVFSILIGIVCALVLYYRVPVARQIVEIYIELSRNTPLVIQLFFLYFGLPKIGITFNSHACAVIGLSFLGGSYMCEAFRSGLESVTKGQRESGLSIGLTEFQLVTNVILPQAFTVSFPAIGANVIFLLKETSVIGILALMELMYLTRDLIGLYYKTNESLFMLVVAYLIIILPVSIILTVIERRMRYATVGN
>NZ_AP019831.1|WP_155283160.1|2565092_2565770_-|ABC-transporter-permease-subunit
MQLSGIDVIFKGVNLQRLMGGLAVTGQVALVSIVFSILFGIILGIVMTSKNKIIYGILKFYLESMRIIPLLVWLFIIYFGVAKGFGLHIDSETTTIIVFVIWGTAEMMDIVRGAIISLPKIQGESAKALGLDTSQVYRYVLLPQAVRRIAPAAVNLITRMIKTTSLAIFIEVAEVLKIGRQIIEFSSRKNPMAPFWVYLFIFFLYFIVCYPITMLSKKLEKKWVV
>NZ_AP019831.1|WP_173020694.1|2564273_2565035_-|amino-acid-ABC-transporter-ATP-binding-protein
MELSDIKKEYKKGVPALKGVSLSVNKSEVVVILGPSGCGKSTLLRCVNGLEEIQSGEIKLQGNVINKDKTKWHLIRQRIGMVFQSYELFDHMTVMQNLLLGPLKVQKRDKNEVTEQAEKLLERVGLLDKKNSYPRELSGGQKQRIAIIRSLCMNPEIMLFDEVTAALDPEMVREVLDVMLELAKEGMTMIIVTHEMEFAKAVADRIVFMDSGEVVETNYPLEFFRNPKTERAKKFLNIFNFEKKDKVESALLI
>NZ_AP019831.1|WP_026749431.1|2563367_2564216_-|cysteine-ABC-transporter-substrate-binding-protein
MKKNFERFVKIIAILVLGVFAISCGKGEKGSAKPGSIEAIKKAGKIRIGVFGDKPPFGFVDENGKNQGYDIYLAKRLAKDLLGDENKIEFVTMEAANRVEYLLSNKVDITLANFTVTDERKEKVDFAKPYMKVSLGIVSPEGAPIKDVKELKGKKLIVNKGTTAEIYFTKNHPDIELLKYDQNTETFNALLDKRGAALAHDNTLVFAWATENPGFVVDIKELGEQDYIAPAVRKGNKELLDWLNAEIDALTKEGFFEKAYKATLEPVYGNKVDPKTVIIEKK
>NZ_AP019831.1|WP_146997573.1|2563065_2563284_+|hypothetical-protein
MRLDKIILEQEIINQRIDMLQEIINVSNEKLMNYQTKESQNMYGILNQLLLKDVLENYDGTLQELIKKHNSK
>NZ_AP019831.1|WP_026749429.1|2562205_2562988_+|hypothetical-protein
MGIWNLIENAIEGAADFVRNTGIIDKIVEIGEGIADWFKDVFNIGDAPSYDKDNATIDETKKVNEILQTYIEKCLNISEKYDNISKEEINKYFSQIKNSLIDINKISENNTENSDKVIEDYIFDSLELNRNTTLKSLDKIYSNEIKDAYSLSNFELLDILKMEQGREKKKKMNAFSVETLTEANEFLFDELKNSINQQQNLVDKKLRDYMYSREEETRRSIEKINEILDSVKTGEKEKQELKNSYVELLDEVKLFDEIFA
>NZ_AP019831.1|WP_155283159.1|2560675_2562205_+|dynamin-family-protein
MLNLEQYIRNNNEELINIHWNETINEYVKKLNASKVLFKNLSEKEYFKSTDTLKGNTFFKEINTEISRYISDSKNPSYQIAIVGAVKAGKSTLINALIGYDLASTNVTPETATLTKIKTTDKNSITVKFYSREEWKKIWNDAQKSTNATIFKEEFDNLRAKEIESEMLGKSDIFKEFDNLDSMKDEIKKWTSSHAREHYFVKEIEIGVEKLNLPPQVCLVDTPGLNDPVQYRSNITSEYIHSANAVIICVNAKTLRNEEIATILDVLTKAQDKKDKVYILGTQIDIMNSQADWEQQQEEWLKHLKEKQFYGSLDMAKKQLIGVSSYFYSNAIKLSSDTDIDSLEDSIDDLVKKEKMTKQDRRELLRKDNITPEDIEQIKNMLIDYSNIEIVNDNIQNKLILGFNESLKNDFLNRYNYLKNKIETFKKEHIEKIQGNINSFEQSENELKQQILQNERQKEELETLNRRLRLKIRETTQAFNTDFEELNSNFRNLMREIKKVKFEEESEDK
>NZ_AP019831.1|WP_146997570.1|2559158_2559977_-|Cof-type-HAD-IIB-family-hydrolase
MNYKLIATDMDGTLLDEEHGITSENVEAIVKVQKEKGVKFVLASGRPSYAMFEYAKELQMDKYEGYVLAFNGGELIDMKTNEVIFHEGLGKKDIENVYKVSKEINVPMILYVGDTIYGTEATDGVMYETNQCKMKFQKFDSLEDLEKKGIDKTTKCMIIGTPEEVLMAEEHMNKVHGNDYFIAISKPIFLEIANKNVDKGKTLKKLGEIENIKPEEMIAVGDSANDKPLLEYVGMPVAVENAIPEIKSISKFISTSNVKHGLKTTIEEFFEF
>NZ_AP019831.1|WP_155283158.1|2558218_2559079_-|GyrI-like-domain-containing-protein
MIKAFNETMKYIEDTLTDRIDERKIALLSGYSYPLFSRMFSIMVDYPLSEYIRFRKLSCAAIDLRESDEKIIEIAFKYGYESQDSFSLAFKKFHGHTPKEVRKGSAFQIFSPIRLSLSIEGGKNMDIKVMKKSAFKIAGLVERIEEGGDFPNVWDKLFKKVSPEKLENLGNRQSYGACYEIEKNENCESKFTVNYMAGYDIQNVTEANDLGLNILEVPEAEYAVVKLKGIVPNCIHEGWKYVTGTFFPEQGYRHAGTPDFEVYGEGDMYSSDYEMELWVPIVKDKN
>NZ_AP019831.1|WP_155283157.1|2556291_2557245_+|ATPase
MKLQEITEKFKNEINQDKISASYLFYGDKRVDLLSYALMFSKMIMTKDVQNDSEKEKIERLIDNFQHPDIEIINKNNENIKIDEVREIIYSSIESSFNSPKKIFILCGIENLRKESSNALLKILEEPPQNVYFILLSRTLNIISTIKSRTIKFHLSGMNNDELGVSKETYYFFDGNENDILEFKKQNLSLDDIKFKINTVEDILQIIFEMKNYATGELAIKNNLDLMIKYNKSIELLARRIRFWDIENVYFFINEIENKLKKEKEFLISFLSKFIINVKHSVEAEDLKKLINLKNSIRSNVNVKSVIFNFFDILQSS
>NZ_AP019831.1|WP_155283162.1|2567361_2569152_+|NAD-nucleotidase
MKKLLLLGLTLALFFTVNLEAKTNRKVNKQDSSDSFELNVAHINDHHSHLEEEKMPLKLNGKTVTVHIGGLPRVAQEIKNFRQNNKNTLVLHAGDAVTGTLYYTLFEGKADAELMNAINFDVYTLGNHEFDDGNKFLKAFLDVLKIPVVSANVVPDKGSILEGKWKPYIIKNIGGQKVGIIGLDVVKKTKESSSPGDDIKFFDEIETARKYVNELQSKGINKIILLSHAGYEKNVEIGQKVDGVDLIITGDTHYLLGKEFEQFGLVPEADSYPKKVNSPNGNPVYIAEAWNYSYLLGQMKAKFDKNGVITELTPTPKVLISDDFFEIKNAEGKAVQLNQKEKNEILNSIKNNKNIVAIKNDPTLAKLLERYQKEKTELGKRTVGKITEEIPGGSDNRVPNEHNKDGSFATTLVAESVLHKLRNTGTGNVDFVIGNAGNVRITLNPGVFTYDLAYSLLPFTSNTVFITDITGAEVKQTLEDAIDYVLNGGSTGAFPYGAGIRYEATKEGKLGTRVKKIEVFDFKANKWVPIDAKKSYTLAVNSYIAKGKDGYTTLGKITAQKRGTDTHLSDTKIFIDYLKEKKEIGKPKSTNVIFKY
>NZ_AP019831.1|WP_036095824.1|2569603_2569972_+|nucleotide-pyrophosphohydrolase
MTLKEVQYLIKRIEKGTLDETKDDKSPQQKRENGQRLILKLIEEFGELAENIRKNVRYDGKNIKGTIEEEVFDVFYYIIAIANDYEIDLEKIFYIKDEVNEVKYDREFSIYEARNKWKSMKK
>NZ_AP019831.1|WP_155283163.1|2570089_2571745_+|5'-nucleotidase-C-terminal-domain-containing-protein
MTAKNTNTSFKKKEVSIKILGTSDVHGRVLAWNYAADEEDKSGSYAQISTLVKKIRKKNKNVILVEVGDAIQDNWIEKFAMTPKHPIPEILNYMGYDIFVPGNHEFNFGMPTLSNILRDMKFKKLTANLYYNENAENDTNFSKDKSRYLDATTIIEKDGVKIGIIGLSTPMSAQFEEDTGYLNDFYFVSPVKETQRQIKKLKEEGANAIVVAAHMGIENENGIPETGVKDLANAVPEIDVIVAGHMHQNIQKEIINGVLITEPHRYGTVISEVDLKFEVIGENIKLISKDSTTIPVKNEKPDKKIEEIYKPFHRRLCTIANEEIGETLNDMIPKEKHHGVSAAFGKDTGMSSFITDVELYYSGADVVSFAYNYENVKLDKGKIRRKDIVYNYRYTGGDVTIYEMTGKQLKDYMEWAADYFDTIQAGDTEYRYNPERANGKYVTFDIFGGVKYKIDLRNEKGSKITNLMLKNGTKITPEMKLKVGMNAYRFEQLARKGGIFDGQEIPALWASKEAIGNIKGTIQNMMIDYIRNVKNGVIEGKSHNNWEIIGL
>NZ_AP019831.1|WP_051354473.1|2571955_2572681_+|hypothetical-protein
MSFGNDETVIGEKLNKLLAILKKDERNYIVSEDIITIYESKIGKDYEKYLDLFTKYTPYDYEKLFAKMVYYRGTGKKDKSDNYYKEIERKYSNTPIMEIIKIYNTANENDRQVQTKKVLNLLKSEEVKRQVGMTDEEVHSMNLTYTLAQVRKYYNNGEIEKSVSEYINNVANASVSNEVRDYNRRKETLLLLNALMVNEEITNKKLREQNKQKLENTYISKEIKKATVKDANYLDKYLNEM
>NZ_AP019831.1|WP_146997579.1|2572907_2574218_+|phosphopyruvate-hydratase
MTRIEDIYAREILDSRGNPTVEVEVYLEGGAMGRASVPSGASTGVHEAVELRDGDKSRYLGQGVLQAVENVNKVIAEHLIGFDALDQVAIDKAMIELDGTPNKGKLGANAILGVSLAVAKAAANQLGIPLYRYLGGVNAKELPVPMMNILNGGSHADSAVDVQEFMVQPVGAKTYKEALRMGSEIFHHLGKILKANGDSTNVGNEGGYAPSNINGTEGALDVISQAVEAAGYKLGDDITFAMDAASSEFATKNADGSYTYTFKREGGVVRNSDEMVEWYKHLTSKYPIVSIEDGLAEDDWDGFKKLTDAIGKDVQLVGDDLFVTNTQRLADGIEKGIANSILIKVNQIGTLTETLDAIEMAKKAGYTAVVSHRSGETEDDTIADIAVATNAGQIKTGSASRTDRMAKYNQLLRIEDDLAEEAVYEGKKAFYNINIK
>NZ_AP019831.1|WP_026749440.1|2574381_2574789_+|adhesion-protein-FadA
MKKVGILFVLLSALSFSAASSKSSKTTTNQTVTGRFNQLEAEYERLVNMENQEYSKLKANAEAASNKLAEKEAQKAQIEERIAKIEAAADSKAFKAQYSELAKQYKAVVKALDSEIKSLSTTVENFAAIEALKGN
>NZ_AP019831.1|WP_026749441.1|2574869_2575283_+|adhesion-protein-FadA
MKKKLAVLLGVLVLSSVSFAAPKAKAAAKPAAGGSIESSLSNLENQLVKLQQMEDAKFREQEAQANAAAQRLSNYTAMQAKIDERIAEIEANVDTSIFGKEFKAKVTEYKNLRNQLDKEIAKEQQVLDNFELIKSLR
>NZ_AP019831.1|WP_155283164.1|2575612_2576503_+|EamA-family-transporter
MQTQKKLHGMLLASLASSLWAISGISGEILFKKFNFSSDWLVSTRTLISGILLSAIVIFIEKKSVLKPLKNKKDCLGIILFGTAGMYLVQYTYFKTIELSNVSFATILQFTAPFFIFVYESAKNRKLPSVSTIILLFMTILGVVFIATKGNFSNLSVSMEALVFGLVSAIMIAFYSTYPKKLLKKYGSITVVGWGMIVGSIISNIIHPIWKIEGNVNAKSIIQVIIVVILGTSIAYLIYIASLNYISSSLAGILTAFEPVLAAILSVIIFGLKFSSVEIVGFVLVFVSIFILEKRL
>NZ_AP019831.1|WP_146997582.1|2576602_2577391_+|META-domain-containing-protein
MKKIFVLIGIFAMFVVNCFILSAAQTVNLNGTSWQLSRIRQNGVNLEIPRNTKITVSFSGNKISGFSGINRYNGTYRVRNNSTLSTDISTTLMGGSEELMNFEMAFLDILQSSPKINYNKGTLTLRNSNGDTLSFNKSSNSNNQSDENSLSRLTKELSGTDWKLVNMNGKEVRNAGITISFSGNKINGNSGINSYFSDYIITAGNITIGTVGSTEMAGSDSLMKTERQYIELLQNAKKIELVNKTTLVLTTNRGKTLTFEKL
>NZ_AP019831.1|WP_026749444.1|2577590_2578238_+|C40-family-peptidase
MRKNKFLTAICMLSAFVGSNLHAKTSKTKKVSKPKTSHKPVNNKKSHSGSNTGIYGISSNNKNALIETKMTELRQRHAKAMASGSAQERRKAAVERKLLTSYSKWRGTKYAWGGDSKKGIDCSALTRRVYREAFNKELPRVSQQQIKKGTRVSAKNLKSGDIVYFTPENRTSHTAVYVGNSLFINASSSKGVVMSSLKSPYWRKYFKYGVRAHNT

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_AP019831_3	3.1\|1341629\|40\|NZ_AP019831\|PILER-CR,CRISPRCasFinder,CRT	1341629-1341668	40	NZ_AP019832.1	23447-23486	0	1.0
NZ_AP019831_3	3.1\|1341629\|40\|NZ_AP019831\|PILER-CR,CRISPRCasFinder,CRT	1341629-1341668	40	NZ_AP019831.1	2409289-2409328	0	1.0
NZ_AP019831_3	3.1\|1341629\|40\|NZ_AP019831\|PILER-CR,CRISPRCasFinder,CRT	1341629-1341668	40	NZ_AP019831.1	2464526-2464565	0	1.0
NZ_AP019831_3	3.2\|1341706\|36\|NZ_AP019831\|PILER-CR,CRISPRCasFinder,CRT	1341706-1341741	36	NZ_AP019831.1	1779217-1779252	0	1.0
NZ_AP019831_4	4.3\|1633017\|36\|NZ_AP019831\|CRISPRCasFinder,PILER-CR	1633017-1633052	36	NZ_AP019831.1	2747825-2747860	0	1.0
NZ_AP019831_5	5.1\|1717175\|35\|NZ_AP019831\|CRISPRCasFinder	1717175-1717209	35	NZ_AP019831.1	2004411-2004445	0	1.0
NZ_AP019831_1	1.5\|1141004\|37\|NZ_AP019831\|CRISPRCasFinder,CRT,PILER-CR	1141004-1141040	37	NZ_AP019831.1	2820926-2820962	1	0.973

1. spacer 3.1|1341629|40|NZ_AP019831|PILER-CR,CRISPRCasFinder,CRT matches to position: 23447-23486, mismatch: 0, identity: 1.0

cgttaatatttccactccgaatggccgtggtgtaagtatt	CRISPR spacer
cgttaatatttccactccgaatggccgtggtgtaagtatt	Protospacer
****************************************

2. spacer 3.1|1341629|40|NZ_AP019831|PILER-CR,CRISPRCasFinder,CRT matches to position: 2409289-2409328, mismatch: 0, identity: 1.0

cgttaatatttccactccgaatggccgtggtgtaagtatt	CRISPR spacer
cgttaatatttccactccgaatggccgtggtgtaagtatt	Protospacer
****************************************

3. spacer 3.1|1341629|40|NZ_AP019831|PILER-CR,CRISPRCasFinder,CRT matches to position: 2464526-2464565, mismatch: 0, identity: 1.0

cgttaatatttccactccgaatggccgtggtgtaagtatt	CRISPR spacer
cgttaatatttccactccgaatggccgtggtgtaagtatt	Protospacer
****************************************

4. spacer 3.2|1341706|36|NZ_AP019831|PILER-CR,CRISPRCasFinder,CRT matches to position: 1779217-1779252, mismatch: 0, identity: 1.0

attccaaaattatctgaacattgctttgaaacaata	CRISPR spacer
attccaaaattatctgaacattgctttgaaacaata	Protospacer
************************************

5. spacer 4.3|1633017|36|NZ_AP019831|CRISPRCasFinder,PILER-CR matches to position: 2747825-2747860, mismatch: 0, identity: 1.0

ttcggttgtgttggaagccattatcttttttaggtt	CRISPR spacer
ttcggttgtgttggaagccattatcttttttaggtt	Protospacer
************************************

6. spacer 5.1|1717175|35|NZ_AP019831|CRISPRCasFinder matches to position: 2004411-2004445, mismatch: 0, identity: 1.0

tagcggcagatccaattgaaggtggcatttcaact	CRISPR spacer
tagcggcagatccaattgaaggtggcatttcaact	Protospacer
***********************************

7. spacer 1.5|1141004|37|NZ_AP019831|CRISPRCasFinder,CRT,PILER-CR matches to position: 2820926-2820962, mismatch: 1, identity: 0.973

catcatcatcatttaacttgattgcacgttttccagc	CRISPR spacer
catcatcatcatttagcttgattgcacgttttccagc	Protospacer
***************.*********************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_AP019831_2	2.15\|1152540\|37\|NZ_AP019831\|PILER-CR,CRISPRCasFinder,CRT	1152540-1152576	37	NZ_AP019825	Leptotrichia hofstadii strain JCM16775 plasmid pJCM16775-2, complete sequence	8837-8873	0	1.0
NZ_AP019831_3	3.1\|1341629\|40\|NZ_AP019831\|PILER-CR,CRISPRCasFinder,CRT	1341629-1341668	40	NZ_AP019830	Leptotrichia wadei strain JCM16777 plasmid pJCM16777-1, complete sequence	28223-28262	0	1.0
NZ_AP019831_3	3.1\|1341629\|40\|NZ_AP019831\|PILER-CR,CRISPRCasFinder,CRT	1341629-1341668	40	NZ_AP019824	Leptotrichia hofstadii strain JCM16775 plasmid pJCM16775-1, complete sequence	4023-4062	0	1.0
NZ_AP019831_3	3.1\|1341629\|40\|NZ_AP019831\|PILER-CR,CRISPRCasFinder,CRT	1341629-1341668	40	NZ_AP019832	Leptotrichia trevisanii strain JMUB3870 plasmid pJMUB3870-1, complete sequence	23447-23486	0	1.0
NZ_AP019831_3	3.1\|1341629\|40\|NZ_AP019831\|PILER-CR,CRISPRCasFinder,CRT	1341629-1341668	40	NZ_AP019847	Leptotrichia hongkongensis strain JMUB5056 plasmid pJMUB5056, complete sequence	183-222	1	0.975
NZ_AP019831_2	2.10\|1152215\|36\|NZ_AP019831\|PILER-CR,CRISPRCasFinder,CRT	1152215-1152250	36	NZ_AP019825	Leptotrichia hofstadii strain JCM16775 plasmid pJCM16775-2, complete sequence	7401-7436	2	0.944
NZ_AP019831_2	2.19\|1152801\|36\|NZ_AP019831\|PILER-CR,CRISPRCasFinder,CRT	1152801-1152836	36	NZ_AP019842	Leptotrichia wadei strain JMUB3936 plasmid pJMUB3934p1, complete sequence	3380-3415	2	0.944
NZ_AP019831_2	2.19\|1152801\|36\|NZ_AP019831\|PILER-CR,CRISPRCasFinder,CRT	1152801-1152836	36	NZ_AP019843	Leptotrichia wadei strain JMUB3936 plasmid pJMUB3934p2, complete sequence	25347-25382	2	0.944
NZ_AP019831_3	3.1\|1341629\|40\|NZ_AP019831\|PILER-CR,CRISPRCasFinder,CRT	1341629-1341668	40	NZ_AP019837	Leptotrichia wadei strain JMUB3934 plasmid pJMUB3934p2, complete sequence	20301-20340	3	0.925
NZ_AP019831_2	2.9\|1152150\|36\|NZ_AP019831\|PILER-CR,CRISPRCasFinder,CRT	1152150-1152185	36	NZ_AP019842	Leptotrichia wadei strain JMUB3936 plasmid pJMUB3934p1, complete sequence	26326-26361	5	0.861
NZ_AP019831_2	2.29\|1153452\|37\|NZ_AP019831\|PILER-CR,CRISPRCasFinder,CRT	1153452-1153488	37	NZ_AP019825	Leptotrichia hofstadii strain JCM16775 plasmid pJCM16775-2, complete sequence	15753-15789	6	0.838
NZ_AP019831_2	2.13\|1152410\|36\|NZ_AP019831\|PILER-CR,CRISPRCasFinder,CRT	1152410-1152445	36	NZ_CP015809	Borrelia mayonii strain MN14-1539 plasmid lp54	21593-21628	8	0.778
NZ_AP019831_2	2.13\|1152410\|36\|NZ_AP019831\|PILER-CR,CRISPRCasFinder,CRT	1152410-1152445	36	NZ_CP015795	Borrelia mayonii strain MN14-1420 plasmid lp54, complete sequence	21609-21644	8	0.778
NZ_AP019831_2	2.18\|1152736\|36\|NZ_AP019831\|PILER-CR,CRISPRCasFinder,CRT	1152736-1152771	36	MN694255	Marine virus AFVG_250M362, complete genome	31461-31496	9	0.75
NZ_AP019831_1	1.11\|1141396\|37\|NZ_AP019831\|CRISPRCasFinder,CRT,PILER-CR	1141396-1141432	37	NZ_CP018934	Bacillus cereus strain ISSFR-9F plasmid unnamed1, complete sequence	8623-8659	10	0.73
NZ_AP019831_1	1.11\|1141396\|37\|NZ_AP019831\|CRISPRCasFinder,CRT,PILER-CR	1141396-1141432	37	NZ_CP018934	Bacillus cereus strain ISSFR-9F plasmid unnamed1, complete sequence	84540-84576	10	0.73
NZ_AP019831_1	1.11\|1141396\|37\|NZ_AP019831\|CRISPRCasFinder,CRT,PILER-CR	1141396-1141432	37	NZ_CP018936	Bacillus cereus strain JEM-2 plasmid unnamed1, complete sequence	61392-61428	10	0.73
NZ_AP019831_1	1.11\|1141396\|37\|NZ_AP019831\|CRISPRCasFinder,CRT,PILER-CR	1141396-1141432	37	NZ_CP018932	Bacillus cereus strain ISSFR-3F plasmid unnamed, complete sequence	52100-52136	10	0.73
NZ_AP019831_1	1.25\|1142310\|36\|NZ_AP019831\|CRISPRCasFinder,CRT,PILER-CR	1142310-1142345	36	NC_018683	Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence	211379-211414	10	0.722
NZ_AP019831_1	1.25\|1142310\|36\|NZ_AP019831\|CRISPRCasFinder,CRT,PILER-CR	1142310-1142345	36	NZ_CP021809	Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence	414033-414068	10	0.722
NZ_AP019831_1	1.26\|1142375\|36\|NZ_AP019831\|CRISPRCasFinder,CRT,PILER-CR	1142375-1142410	36	NZ_CP032837	Klebsiella pneumoniae strain INF237 plasmid pINF237_04, complete sequence	9947-9982	10	0.722
NZ_AP019831_2	2.18\|1152736\|36\|NZ_AP019831\|PILER-CR,CRISPRCasFinder,CRT	1152736-1152771	36	MN693220	Marine virus AFVG_25M60, complete genome	57363-57398	11	0.694

1. spacer 2.15|1152540|37|NZ_AP019831|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019825 (Leptotrichia hofstadii strain JCM16775 plasmid pJCM16775-2, complete sequence) position: , mismatch: 0, identity: 1.0

gaacattgatagagaaataaaataactctttacaaat	CRISPR spacer
gaacattgatagagaaataaaataactctttacaaat	Protospacer
*************************************

2. spacer 3.1|1341629|40|NZ_AP019831|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019830 (Leptotrichia wadei strain JCM16777 plasmid pJCM16777-1, complete sequence) position: , mismatch: 0, identity: 1.0

cgttaatatttccactccgaatggccgtggtgtaagtatt	CRISPR spacer
cgttaatatttccactccgaatggccgtggtgtaagtatt	Protospacer
****************************************

3. spacer 3.1|1341629|40|NZ_AP019831|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019824 (Leptotrichia hofstadii strain JCM16775 plasmid pJCM16775-1, complete sequence) position: , mismatch: 0, identity: 1.0

cgttaatatttccactccgaatggccgtggtgtaagtatt	CRISPR spacer
cgttaatatttccactccgaatggccgtggtgtaagtatt	Protospacer
****************************************

4. spacer 3.1|1341629|40|NZ_AP019831|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019832 (Leptotrichia trevisanii strain JMUB3870 plasmid pJMUB3870-1, complete sequence) position: , mismatch: 0, identity: 1.0

cgttaatatttccactccgaatggccgtggtgtaagtatt	CRISPR spacer
cgttaatatttccactccgaatggccgtggtgtaagtatt	Protospacer
****************************************

5. spacer 3.1|1341629|40|NZ_AP019831|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019847 (Leptotrichia hongkongensis strain JMUB5056 plasmid pJMUB5056, complete sequence) position: , mismatch: 1, identity: 0.975

cgttaatatttccactccgaatggccgtggtgtaagtatt	CRISPR spacer
cgttaatatttccactccgaatggccgtggtgtcagtatt	Protospacer
********************************* ******

6. spacer 2.10|1152215|36|NZ_AP019831|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019825 (Leptotrichia hofstadii strain JCM16775 plasmid pJCM16775-2, complete sequence) position: , mismatch: 2, identity: 0.944

ttatatatgctagagtcagcacagaaatgcaggaag	CRISPR spacer
ttatatatgctagggttagcacagaaatgcaggaag	Protospacer
*************.**.*******************

7. spacer 2.19|1152801|36|NZ_AP019831|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019842 (Leptotrichia wadei strain JMUB3936 plasmid pJMUB3934p1, complete sequence) position: , mismatch: 2, identity: 0.944

tttgatttagataaaaggttgcagacaattgtaatc	CRISPR spacer
tttgatctggataaaaggttgcagacaattgtaatc	Protospacer
******.*.***************************

8. spacer 2.19|1152801|36|NZ_AP019831|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019843 (Leptotrichia wadei strain JMUB3936 plasmid pJMUB3934p2, complete sequence) position: , mismatch: 2, identity: 0.944

tttgatttagataaaaggttgcagacaattgtaatc	CRISPR spacer
tttgatctggataaaaggttgcagacaattgtaatc	Protospacer
******.*.***************************

9. spacer 3.1|1341629|40|NZ_AP019831|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019837 (Leptotrichia wadei strain JMUB3934 plasmid pJMUB3934p2, complete sequence) position: , mismatch: 3, identity: 0.925

cgttaatatttccactccgaatggccgtggtgta--agtatt	CRISPR spacer
cgttaatatttccactccgaatggccgtggtgtgttagta--	Protospacer
*********************************.  ****

10. spacer 2.9|1152150|36|NZ_AP019831|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019842 (Leptotrichia wadei strain JMUB3936 plasmid pJMUB3934p1, complete sequence) position: , mismatch: 5, identity: 0.861

ctctgattttcctatccattatccaccacctctccc	CRISPR spacer
attttgttttcctatccattatccaccacctctacc	Protospacer
 *.* .*************************** **

11. spacer 2.29|1153452|37|NZ_AP019831|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019825 (Leptotrichia hofstadii strain JCM16775 plasmid pJCM16775-2, complete sequence) position: , mismatch: 6, identity: 0.838

tttaatactcccttatttcatttttacccccttttga	CRISPR spacer
ctcacgcctcccttatttcatttttacctccttttga	Protospacer
.*.*   *********************.********

12. spacer 2.13|1152410|36|NZ_AP019831|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015809 (Borrelia mayonii strain MN14-1539 plasmid lp54) position: , mismatch: 8, identity: 0.778

taaaaatttataaataaatttaaatcatatttatta	CRISPR spacer
aaagaaagcttagaaaaatttaaatcatatttatta	Protospacer
 **.**  . **.* *********************

13. spacer 2.13|1152410|36|NZ_AP019831|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015795 (Borrelia mayonii strain MN14-1420 plasmid lp54, complete sequence) position: , mismatch: 8, identity: 0.778

taaaaatttataaataaatttaaatcatatttatta	CRISPR spacer
aaagaaagcttagaaaaatttaaatcatatttatta	Protospacer
 **.**  . **.* *********************

14. spacer 2.18|1152736|36|NZ_AP019831|PILER-CR,CRISPRCasFinder,CRT matches to MN694255 (Marine virus AFVG_250M362, complete genome) position: , mismatch: 9, identity: 0.75

ctcctaaataatctttttgtttattgtttgcaggtt	CRISPR spacer
tttttaaataatctttttgtttaatatttgataatt	Protospacer
.*..******************* *.****  ..**

15. spacer 1.11|1141396|37|NZ_AP019831|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP018934 (Bacillus cereus strain ISSFR-9F plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.73

tttaatgtagatgaaataaatcctattgtaatgaaat	CRISPR spacer
gttaatgcagatgaaataaatgctattaaagtagctt	Protospacer
 ******.************* *****. *.*..  *

16. spacer 1.11|1141396|37|NZ_AP019831|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP018934 (Bacillus cereus strain ISSFR-9F plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.73

tttaatgtagatgaaataaatcctattgtaatgaaat	CRISPR spacer
gttaatgcagatgaaataaatgctattaaagtagctt	Protospacer
 ******.************* *****. *.*..  *

17. spacer 1.11|1141396|37|NZ_AP019831|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP018936 (Bacillus cereus strain JEM-2 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.73

tttaatgtagatgaaataaatcctattgtaatgaaat	CRISPR spacer
gttaatgcagatgaaataaatgctattaaagtagctt	Protospacer
 ******.************* *****. *.*..  *

18. spacer 1.11|1141396|37|NZ_AP019831|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP018932 (Bacillus cereus strain ISSFR-3F plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.73

tttaatgtagatgaaataaatcctattgtaatgaaat	CRISPR spacer
gttaatgcagatgaaataaatgctattaaagtagctt	Protospacer
 ******.************* *****. *.*..  *

19. spacer 1.25|1142310|36|NZ_AP019831|CRISPRCasFinder,CRT,PILER-CR matches to NC_018683 (Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence) position: , mismatch: 10, identity: 0.722

ctccaagcgaagtatttttagtaattccgaaagacg	CRISPR spacer
tggcaagcgaagtatttttggtcattccgatgaatt	Protospacer
.  ****************.** ******* ..*.

20. spacer 1.25|1142310|36|NZ_AP019831|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021809 (Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence) position: , mismatch: 10, identity: 0.722

ctccaagcgaagtatttttagtaattccgaaagacg	CRISPR spacer
tggcaagcgaagtatttttggtcattccgatgaatt	Protospacer
.  ****************.** ******* ..*.

21. spacer 1.26|1142375|36|NZ_AP019831|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032837 (Klebsiella pneumoniae strain INF237 plasmid pINF237_04, complete sequence) position: , mismatch: 10, identity: 0.722

cgaaaagatgtttatttttttcagaaaaattataaa	CRISPR spacer
gggtttattgtttattttttccagcaaaattataac	Protospacer
 *.   . ************.*** **********

22. spacer 2.18|1152736|36|NZ_AP019831|PILER-CR,CRISPRCasFinder,CRT matches to MN693220 (Marine virus AFVG_25M60, complete genome) position: , mismatch: 11, identity: 0.694

ctcctaaataatctttttgtttattgtttgcaggtt	CRISPR spacer
tctctaaataatctttttcttttttgtttaactcta	Protospacer
...*************** *** ******.    *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

162066 : 229873

uncultured_Mediterranean_phage(18.18%)

tail,integrase,transposase,tRNA,head

attL 191441:191459|attR 230344:230362

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_173020632.1\|162066_162420_-\|transposase	transposase	NA	NA	NA	NA
WP_173020633.1\|162488_163043_-\|transposase	transposase zinc-binding domain-containing protein	NA	NA	NA	NA
WP_026748415.1\|163406_163838_+	hypothetical protein	NA	NA	NA	NA
WP_155282314.1\|164535_165087_-	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_155282315.1\|165176_165653_-\|head,tail	phage head-tail adapter protein	NA	NA	NA	NA
WP_155282316.1\|165756_167229_-	hypothetical protein	NA	NA	NA	NA
WP_026748419.1\|167436_168330_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_026748420.1\|168491_168815_+	DNA-binding protein	NA	NA	NA	NA
WP_155282317.1\|169024_169885_+	SIS domain-containing protein	NA	NA	NA	NA
WP_155282318.1\|170023_171445_+	6-phospho-beta-glucosidase	NA	NA	NA	NA
WP_155282319.1\|171550_172234_+	hypothetical protein	NA	NA	NA	NA
WP_155282320.1\|172274_172661_+	VOC family protein	NA	NA	NA	NA
WP_036095263.1\|172901_173624_+	DNA repair protein RadC	A0A1B2LRS6	Wolbachia_phage	2.2e-23	34.2
WP_026748426.1\|173620_174127_+	hypothetical protein	NA	NA	NA	NA
WP_026748427.1\|174604_175690_+	DUF4935 domain-containing protein	NA	NA	NA	NA
WP_155282321.1\|175988_177209_+	bifunctional glucose-1-phosphatase/inositol phosphatase	NA	NA	NA	NA
WP_026748429.1\|177677_180290_+	DUF87 domain-containing protein	A0A218M9A2	Mycobacterium_phage	2.5e-85	46.8
WP_036095264.1\|180452_181499_+	rod shape-determining protein	NA	NA	NA	NA
WP_026748431.1\|181619_182252_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	1.1e-18	37.6
WP_026748432.1\|182390_183077_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_026748433.1\|183101_183767_+	HAD-IB family phosphatase	NA	NA	NA	NA
WP_026748434.1\|183790_183994_+	hypothetical protein	NA	NA	NA	NA
WP_026748435.1\|184020_184758_+	hypothetical protein	NA	NA	NA	NA
WP_006805047.1\|184827_185127_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_026748436.1\|185147_185894_+	DUF4253 domain-containing protein	NA	NA	NA	NA
WP_026748437.1\|185915_187379_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_026748438.1\|187441_188878_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_026748439.1\|188900_191012_+	PASTA domain-containing protein	NA	NA	NA	NA
WP_155282322.1\|191060_193343_+	primosomal protein N'	NA	NA	NA	NA
191441:191459	attL	NA	NA	NA	NA
WP_146995817.1\|193495_194314_+	di-trans,poly-cis-decaprenylcistransferase	R9W0U9	Flavobacterium_phage	3.1e-13	31.3
WP_155282323.1\|194303_195230_+	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_026748443.1\|195285_196524_+\|tRNA	tyrosine--tRNA ligase	K4F5T3	Cronobacter_phage	1.5e-24	26.6
WP_026748444.1\|197292_197661_+	holo-ACP synthase	NA	NA	NA	NA
WP_146995819.1\|197682_198972_+	glutaredoxin	NA	NA	NA	NA
WP_146995820.1\|199087_199903_+	toxin-antitoxin system YwqK family antitoxin	NA	NA	NA	NA
WP_026748447.1\|199935_200838_+	DNA-binding protein WhiA	NA	NA	NA	NA
WP_155282324.1\|200866_201886_+	tetraacyldisaccharide 4'-kinase	NA	NA	NA	NA
WP_155282325.1\|201940_202729_+	hypothetical protein	NA	NA	NA	NA
WP_155282326.1\|202922_204194_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	2.2e-95	50.5
WP_026748451.1\|204348_205068_+	glycoside hydrolase	NA	NA	NA	NA
WP_026748452.1\|205254_206238_+	class II fructose-1,6-bisphosphate aldolase	NA	NA	NA	NA
WP_146997999.1\|206953_208567_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	9.2e-147	50.6
WP_026748454.1\|208763_209024_-	HPr family phosphocarrier protein	NA	NA	NA	NA
WP_155282328.1\|209147_210791_-	fibronectin/fibrinogen-binding protein	M1I5P2	Paramecium_bursaria_Chlorella_virus	7.5e-11	36.4
WP_155283248.1\|210852_211758_-	Abi family protein	A0A059NT88	Lactococcus_phage	7.7e-50	36.1
WP_026748456.1\|211976_212639_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_155282329.1\|212782_213415_-	ribulose-phosphate 3-epimerase	NA	NA	NA	NA
WP_155282330.1\|213466_214366_-	ribosome small subunit-dependent GTPase A	NA	NA	NA	NA
WP_026748459.1\|214443_215397_-	PASTA domain-containing protein	NA	NA	NA	NA
WP_155282331.1\|215838_216966_+	SIMPL domain-containing protein	NA	NA	NA	NA
WP_026748461.1\|217063_218125_+	SIMPL domain-containing protein	NA	NA	NA	NA
WP_026748462.1\|218354_219854_+	PTS trehalose transporter subunit IIBC	NA	NA	NA	NA
WP_026748463.1\|221651_222905_+	Glu/Leu/Phe/Val dehydrogenase	NA	NA	NA	NA
WP_173020634.1\|223191_223362_-	hypothetical protein	NA	NA	NA	NA
WP_173020681.1\|223355_223571_-\|transposase	transposase	NA	NA	NA	NA
WP_173020635.1\|223950_224361_-\|transposase	transposase zinc-binding domain-containing protein	NA	NA	NA	NA
WP_026749681.1\|224634_224928_-	GTP cyclohydrolase	NA	NA	NA	NA
WP_155282333.1\|225172_227653_+	AMP-binding protein	A0A1V0SBX8	Catovirus	2.1e-33	24.9
WP_026749679.1\|228907_229873_-\|integrase	site-specific integrase	A0A0E3Y5J2	Fusobacterium_phage	1.0e-20	28.1
230344:230362	attR	NA	NA	NA	NA

DBSCAN-SWA_2

807604 : 881832

Streptococcus_phage(30.0%)

integrase,transposase

attL 800630:800651|attR 834897:834918

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
800630:800651	attL	NA	NA	NA	NA
WP_026749641.1\|807604_808579_+\|integrase	tyrosine-type recombinase/integrase	A0A2H4JAA2	uncultured_Caudovirales_phage	1.3e-34	28.7
WP_155282508.1\|808623_811017_+	DUF4143 domain-containing protein	A0A2H4PQP5	Staphylococcus_phage	1.1e-23	37.1
WP_155282509.1\|811060_814429_+	DEAD/DEAH box helicase family protein	A0A097BY72	Enterococcus_phage	2.0e-18	25.8
WP_155282510.1\|814930_815599_+	sakacin A production response regulator	NA	NA	NA	NA
WP_173020647.1\|815611_817309_+	DnaJ domain-containing protein	NA	NA	NA	NA
WP_026749647.1\|817321_818584_+	DnaJ domain-containing protein	NA	NA	NA	NA
WP_155282512.1\|818620_820435_+	Hsp70 family protein	A0A1V0SH73	Hokovirus	2.4e-74	33.4
WP_155282513.1\|820522_821596_+	DKNYY domain-containing protein	NA	NA	NA	NA
WP_155282514.1\|821664_824925_+	DKNYY domain-containing protein	NA	NA	NA	NA
WP_155282515.1\|824989_826801_+	DKNYY domain-containing protein	NA	NA	NA	NA
WP_173020630.1\|829356_829638_+	hypothetical protein	NA	NA	NA	NA
WP_084533572.1\|829604_829955_+	amidohydrolase family protein	NA	NA	NA	NA
WP_155282516.1\|829971_830718_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_026748367.1\|831618_832266_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_026748365.1\|833391_835218_+	DKNYY domain-containing protein	NA	NA	NA	NA
834897:834918	attR	NA	NA	NA	NA
WP_026748364.1\|835506_836205_-	esterase	NA	NA	NA	NA
WP_026748363.1\|836571_837345_+	hypothetical protein	NA	NA	NA	NA
WP_026748361.1\|837825_838743_+	DUF4299 domain-containing protein	NA	NA	NA	NA
WP_026748360.1\|838762_839701_+	hypothetical protein	NA	NA	NA	NA
WP_026748359.1\|839719_840484_+	hypothetical protein	NA	NA	NA	NA
WP_155282517.1\|840504_841599_+	ABC transporter permease	NA	NA	NA	NA
WP_026748357.1\|841639_842014_+	hypothetical protein	NA	NA	NA	NA
WP_155282518.1\|842103_842853_+	hypothetical protein	NA	NA	NA	NA
WP_155282519.1\|843069_844284_+	amidohydrolase	NA	NA	NA	NA
WP_155282520.1\|844631_846320_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	E4ZFI6	Streptococcus_phage	6.6e-63	33.6
WP_009644182.1\|846338_846620_+	hypothetical protein	NA	NA	NA	NA
WP_172618353.1\|846815_847100_-	hypothetical protein	NA	NA	NA	NA
WP_173020632.1\|847066_847420_-\|transposase	transposase	NA	NA	NA	NA
WP_173020633.1\|847488_848043_-\|transposase	transposase zinc-binding domain-containing protein	NA	NA	NA	NA
WP_172618353.1\|848228_848513_-	hypothetical protein	NA	NA	NA	NA
WP_173020682.1\|848479_849037_-\|transposase	transposase	NA	NA	NA	NA
WP_173020648.1\|849043_849454_-\|transposase	transposase zinc-binding domain-containing protein	NA	NA	NA	NA
WP_146996276.1\|849516_849810_+	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_155282522.1\|849831_850047_+	conjugal transfer protein	NA	NA	NA	NA
WP_155282523.1\|850066_850930_+	hypothetical protein	NA	NA	NA	NA
WP_146998314.1\|850947_851211_+	conjugal transfer protein	NA	NA	NA	NA
WP_155282524.1\|851214_851574_+	PrgI family protein	E4ZFJ8	Streptococcus_phage	2.1e-51	87.4
WP_146996281.1\|853949_856082_+	CHAP domain-containing protein	NA	NA	NA	NA
WP_146996282.1\|856093_856333_+	conjugal transfer protein	NA	NA	NA	NA
WP_155282525.1\|857954_859661_+	DNA topoisomerase 3	A0A1X9I6W8	Streptococcus_phage	2.9e-34	35.1
WP_009643971.1\|859748_859928_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_155283252.1\|859945_861364_+	putative DNA binding domain-containing protein	NA	NA	NA	NA
WP_155282526.1\|861537_868890_+	DEAD/DEAH box helicase family protein	A0A248SL14	Klebsiella_phage	6.5e-256	37.3
WP_155282527.1\|869441_870911_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-129	49.7
WP_006906964.1\|873139_873349_+	helix-turn-helix transcriptional regulator	A0A2K5B263	Erysipelothrix_phage	8.6e-13	46.4
WP_146996289.1\|873345_874806_+	SIR2 family protein	NA	NA	NA	NA
WP_146996290.1\|874807_875299_+	TIR domain-containing protein	NA	NA	NA	NA
WP_146996291.1\|875336_875939_+	TIR domain-containing protein	NA	NA	NA	NA
WP_146996292.1\|875913_877044_+	TIR domain-containing protein	NA	NA	NA	NA
WP_146996293.1\|877078_878410_-	relaxase/mobilization nuclease domain-containing protein	NA	NA	NA	NA
WP_009644452.1\|878415_878766_-	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_146998323.1\|879130_879655_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_146998324.1\|880071_880536_+	hypothetical protein	NA	NA	NA	NA
WP_173020683.1\|880983_881832_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_3

1926683 : 1998248

Staphylococcus_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_146997438.1\|1926683_1927862_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_026749501.1\|1928126_1930460_+	patatin-like phospholipase family protein	A0A2H4UUE4	Bodo_saltans_virus	2.1e-14	28.8
WP_026749500.1\|1930570_1930936_+	endoribonuclease L-PSP	NA	NA	NA	NA
WP_155282971.1\|1931257_1932478_+\|transposase	transposase	NA	NA	NA	NA
WP_173020669.1\|1932663_1933623_+\|transposase	transposase zinc-binding domain-containing protein	NA	NA	NA	NA
WP_173020670.1\|1933612_1933897_+	hypothetical protein	NA	NA	NA	NA
WP_173020689.1\|1934218_1934836_+\|transposase	transposase zinc-binding domain-containing protein	NA	NA	NA	NA
WP_026748373.1\|1937077_1937263_-	DNA cytosine methyltransferase	A0A141E0F9	Streptococcus_phage	2.0e-05	50.0
WP_155282972.1\|1937279_1938923_-	hypothetical protein	NA	NA	NA	NA
WP_146997181.1\|1939078_1940314_-	aminoacetone oxidase family FAD-binding enzyme	A0A2H4PQX1	Staphylococcus_phage	6.4e-07	31.3
WP_026748376.1\|1940660_1941419_-	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_026748377.1\|1941569_1942214_-	O-methyltransferase	NA	NA	NA	NA
WP_155282973.1\|1942668_1943712_-	type II secretion system F family protein	NA	NA	NA	NA
WP_169720569.1\|1943768_1944650_-	ROK family protein	NA	NA	NA	NA
WP_155282974.1\|1944732_1945734_-	D-glycero-beta-D-manno-heptose-7-phosphate kinase	R9S8D5	Prochlorococcus_phage	9.5e-17	29.4
WP_155283268.1\|1945898_1947035_-	general secretion pathway protein GspD	NA	NA	NA	NA
WP_155282975.1\|1947112_1947679_-	hypothetical protein	NA	NA	NA	NA
WP_155282976.1\|1947776_1949198_-	hypothetical protein	NA	NA	NA	NA
WP_155282977.1\|1949251_1949851_-	hypothetical protein	NA	NA	NA	NA
WP_026748385.1\|1949867_1950326_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_026748386.1\|1950352_1950811_-	hypothetical protein	NA	NA	NA	NA
WP_026748387.1\|1950825_1951272_-	prepilin peptidase	NA	NA	NA	NA
WP_026748388.1\|1951271_1951721_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_051354405.1\|1952101_1952329_-	hypothetical protein	NA	NA	NA	NA
WP_026748389.1\|1952577_1953489_-	ACP S-malonyltransferase	NA	NA	NA	NA
WP_026748390.1\|1953654_1954020_-	hypothetical protein	NA	NA	NA	NA
WP_155282978.1\|1954128_1955106_-	beta-ketoacyl-ACP synthase 3	NA	NA	NA	NA
WP_026748392.1\|1955294_1955486_-	50S ribosomal protein L32	NA	NA	NA	NA
WP_155282979.1\|1955706_1957005_-	DUF389 domain-containing protein	NA	NA	NA	NA
WP_155282980.1\|1957068_1958316_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_155282981.1\|1962197_1962719_-	DUF1439 domain-containing protein	NA	NA	NA	NA
WP_155282982.1\|1962866_1965695_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	3.3e-280	54.0
WP_026748398.1\|1966473_1967229_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_026748399.1\|1967257_1968127_-	ABC transporter permease	NA	NA	NA	NA
WP_026748400.1\|1968173_1969241_-	ABC transporter permease	NA	NA	NA	NA
WP_146998923.1\|1969233_1970751_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	8.7e-22	32.7
WP_146998924.1\|1970908_1971925_-	hypothetical protein	NA	NA	NA	NA
WP_146998925.1\|1972085_1973870_-	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_146997777.1\|1973879_1974761_-	RNase adapter RapZ	NA	NA	NA	NA
WP_146998926.1\|1975063_1975579_+	hypothetical protein	NA	NA	NA	NA
WP_155282983.1\|1975733_1977284_-	hypothetical protein	NA	NA	NA	NA
WP_155282984.1\|1977669_1978713_+	alcohol dehydrogenase AdhP	A0A2K9L339	Tupanvirus	6.4e-24	23.5
WP_146998929.1\|1978990_1979488_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_146998930.1\|1979571_1980171_-	hypothetical protein	NA	NA	NA	NA
WP_155282985.1\|1980212_1982855_-	autotransporter domain-containing protein	NA	NA	NA	NA
WP_026748411.1\|1983287_1984634_+	magnesium transporter	NA	NA	NA	NA
WP_026748412.1\|1984644_1985991_+	magnesium transporter	NA	NA	NA	NA
WP_026748413.1\|1986066_1986597_+	hypothetical protein	NA	NA	NA	NA
WP_155282986.1\|1986824_1995260_-	autotransporter-associated N-terminal domain-containing protein	NA	NA	NA	NA
WP_146997211.1\|1995637_1996621_-	FAD-dependent oxidoreductase	G3MA85	Bacillus_virus	1.1e-41	34.4
WP_173020690.1\|1997181_1997574_+\|transposase	transposase zinc-binding domain-containing protein	NA	NA	NA	NA
WP_173020691.1\|1997483_1998248_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_4

2466929 : 2528096

Lactobacillus_prophage(13.33%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_146997438.1\|2466929_2468108_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_146997454.1\|2468416_2469517_-	metal ABC transporter permease	NA	NA	NA	NA
WP_155283126.1\|2469520_2470477_-	metal ABC transporter permease	NA	NA	NA	NA
WP_026748720.1\|2470478_2471255_-	metal ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	8.4e-13	28.4
WP_026748721.1\|2471412_2472348_-	zinc ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_026748722.1\|2472340_2473015_-	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_026748723.1\|2473658_2474243_-	biotin transporter BioY	NA	NA	NA	NA
WP_026748724.1\|2474345_2475515_-	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	1.5e-18	25.3
WP_026748725.1\|2475678_2476185_-	hypothetical protein	NA	NA	NA	NA
WP_026748726.1\|2476382_2477264_-	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_026748727.1\|2477342_2477672_-	type II toxin-antitoxin system PemK/MazF family toxin	A9D9Y1	Lactobacillus_prophage	1.6e-13	40.4
WP_018450842.1\|2477665_2477917_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A9D9X7	Lactobacillus_prophage	7.1e-06	45.3
WP_026748728.1\|2478053_2479877_-	molecular chaperone DnaK	A0A0N9QXN8	Chrysochromulina_ericina_virus	3.3e-140	50.4
WP_155283127.1\|2479900_2480581_-	hypothetical protein	NA	NA	NA	NA
WP_026748730.1\|2480600_2481188_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_006805786.1\|2481212_2482223_-	heat-inducible transcription repressor HrcA	NA	NA	NA	NA
WP_026748731.1\|2482957_2483428_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_026748732.1\|2483588_2484341_-\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_026748733.1\|2485299_2485581_-	cupin domain-containing protein	NA	NA	NA	NA
WP_084533597.1\|2485602_2487060_-	transcription termination factor Rho	NA	NA	NA	NA
WP_026748735.1\|2487060_2488389_-\|tRNA	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	NA	NA	NA	NA
WP_173020674.1\|2489138_2489699_+\|transposase	transposase zinc-binding domain-containing protein	NA	NA	NA	NA
WP_173020675.1\|2489783_2490296_+\|transposase	transposase	NA	NA	NA	NA
WP_026748142.1\|2490587_2491691_-	hypothetical protein	NA	NA	NA	NA
WP_026748143.1\|2492233_2493418_-	elongation factor Tu	A0A2K9KZ60	Tupanvirus	4.0e-14	28.2
WP_155283130.1\|2493666_2495376_+	DUF262 domain-containing protein	NA	NA	NA	NA
WP_026749411.1\|2495532_2496018_+	hypothetical protein	NA	NA	NA	NA
WP_026749410.1\|2496017_2496389_+	hypothetical protein	NA	NA	NA	NA
WP_026749409.1\|2496424_2498605_+	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	6.1e-85	34.9
WP_026749408.1\|2498660_2499407_+	hypothetical protein	NA	NA	NA	NA
WP_155283131.1\|2499445_2499733_+	hypothetical protein	NA	NA	NA	NA
WP_155283132.1\|2499793_2500480_+	2,3-diphosphoglycerate-dependent phosphoglycerate mutase	NA	NA	NA	NA
WP_026749405.1\|2501388_2501787_+	DUF2721 domain-containing protein	NA	NA	NA	NA
WP_155283133.1\|2502013_2503348_+	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A0N7G7P8	Chrysochromulina_ericina_virus	7.6e-38	37.8
WP_155283134.1\|2503470_2504463_+	ribose-phosphate diphosphokinase	A0A1V0SHF7	Hokovirus	4.1e-44	35.7
WP_155283135.1\|2504446_2505058_+	threonylcarbamoyl-AMP synthase	A0A291ATS8	Pandoravirus	6.2e-11	26.0
WP_026749401.1\|2505186_2505660_+	hypothetical protein	NA	NA	NA	NA
WP_155283136.1\|2505720_2506941_+	Flp pilus assembly complex ATPase component TadA	NA	NA	NA	NA
WP_173020693.1\|2507024_2508533_-	RnfABCDGE type electron transport complex subunit D	NA	NA	NA	NA
WP_155283137.1\|2508529_2509903_-	electron transport complex subunit RsxC	NA	NA	NA	NA
WP_155283275.1\|2510139_2511228_-	nitronate monooxygenase	NA	NA	NA	NA
WP_155283138.1\|2511340_2511802_-	hypothetical protein	NA	NA	NA	NA
WP_155283139.1\|2512478_2512796_+	thioredoxin fold domain-containing protein	A0A1J0GW78	Streptomyces_phage	2.1e-10	34.1
WP_155283140.1\|2512861_2513884_+	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	2.1e-88	48.9
WP_155283141.1\|2513917_2514955_+	DUF3829 domain-containing protein	NA	NA	NA	NA
WP_026749392.1\|2514991_2515594_+	hypothetical protein	NA	NA	NA	NA
WP_155283142.1\|2515623_2516859_+	aminopeptidase	NA	NA	NA	NA
WP_084533658.1\|2517392_2519666_-	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	J9Q7H7	Salmonella_phage	6.1e-11	38.8
WP_155283276.1\|2519960_2520536_+	HD domain-containing protein	NA	NA	NA	NA
WP_155283143.1\|2520686_2522969_+	ribonuclease R	Q0GXV6	Lactococcus_phage	5.1e-66	33.9
WP_155283144.1\|2522994_2523444_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	6.3e-29	47.2
WP_155283145.1\|2523550_2524345_-	precorrin-6A reductase	NA	NA	NA	NA
WP_026749385.1\|2525310_2525940_-	histidine phosphatase family protein	NA	NA	NA	NA
WP_051354467.1\|2526653_2527040_+\|transposase	transposase	NA	NA	NA	NA
WP_155283146.1\|2527272_2527659_-\|transposase	transposase	NA	NA	NA	NA
WP_173020676.1\|2527655_2528096_-\|transposase	transposase family protein	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: NZ_AP019831.1|WP_026749678.1|229875_230250_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr_ID: NZ_AP019831.1|WP_155282841.1|1582461_1583043_-|GNAT-family-N-acetyltransferase

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_AP019831.1|WP_026749678.1|229875_230250_-|hypothetical-protein

229875_230250_-

124 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|84	0.9435483870967742	1	1.0

NZ_AP019831.1|WP_155282841.1|1582461_1583043_-|GNAT-family-N-acetyltransferase

1582461_1583043_-

193 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|89	0.6597938144329897	1	1.0

2. NZ_AP019832

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_AP019831

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

2. NZ_AP019832

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection