CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NZ_CP042156	Staphylococcus aureus strain B4-59C plasmid pSALNC1.4-2, complete sequence	0 crisprs	NA	0	0	0
NZ_CP042154	Staphylococcus aureus strain B4-59C plasmid pSALNC14, complete sequence	0 crisprs	NA	0	0	0
NZ_CP042155	Staphylococcus aureus strain B4-59C plasmid pSALNC2.8, complete sequence	0 crisprs	NA	0	0	0
NZ_CP042153	Staphylococcus aureus strain B4-59C chromosome, complete genome	11 crisprs	cas3,DEDDh,DinG,csa3,RT,WYL	6	2	9

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP042153_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042153_1

473400-473501

Orphan

Consensus_repeat	Method
TTATGAATTGAGTATTAAATTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042153_1

>merge|NZ_CP042153|1|473400-473501|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTGAAAGTAAATTACAGTTCTATAGGTTTATAAAAAATCAGTTTTTAAATCAAAGCTATATATGAATTGAGTATTAAATTTG

>NZ_CP042153|1|1|473400-473501|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTG	AAAGTAAATTACAGTTCTATAGGTTTATAAAAAATCAGTTTTTAAATCAAAGCTAT
ATATGAATTGAGTATTAAATTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042153.1\|WP_000041880.1\|482273_482978_-\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NZ_CP042153.1\|WP_001792089.1\|472624_472723_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_071621345.1\|472933_473191_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000746679.1\|466646_467273_-\|NDxxF-motif-lipoprotein	unknown	unknown	gnl\|CDD\|380196
NZ_CP042153.1\|WP_000956137.1\|473517_474474_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274008
NZ_CP042153.1\|WP_000551643.1\|481345_481882_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000868256.1\|465993_466377_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000930514.1\|467716_469240_-\|alkyl-hydroperoxide-reductase-subunit-F	unknown	unknown	gnl\|CDD\|237942
NZ_CP042153.1\|WP_000211677.1\|464959_465169_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_114306602.1\|479691_481233_+\|glutamine-hydrolyzing-GMP-synthase	unknown	unknown	gnl\|CDD\|234614
NZ_CP042153.1\|WP_000793023.1\|476894_478163_+\|purine-permease	unknown	unknown	gnl\|CDD\|274468
NZ_CP042153.1\|WP_000264071.1\|478200_479667_+\|IMP-dehydrogenase	unknown	unknown	gnl\|CDD\|235507
NZ_CP042153.1\|WP_000159787.1\|483376_483649_-\|transposase	unknown	unknown	gnl\|CDD\|225511
NZ_CP042153.1\|WP_000763767.1\|475396_475804_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378584
NZ_CP042153.1\|WP_000421410.1\|476316_476895_+\|xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181705
NZ_CP042153.1\|WP_001287097.1\|470316_471072_+\|oxygen-insensitive-NADPH-nitroreductase	unknown	unknown	gnl\|CDD\|380322
NZ_CP042153.1\|WP_000991014.1\|471151_472540_-\|L-cystine-transporter	unknown	unknown	gnl\|CDD\|224736
NZ_CP042153.1\|WP_000052781.1\|469255_469825_-\|peroxiredoxin	unknown	unknown	gnl\|CDD\|211789
NZ_CP042153.1\|WP_000394698.1\|474591_475254_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000158375.1\|465346_465928_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483

Protein	Function_ID	Function_description	E-value
NZ_CP042153.1\|WP_000041880.1\|482273_482978_-\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	5.38181e-08
NZ_CP042153.1\|WP_000158375.1\|465346_465928_+\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	2.4566e-49
NZ_CP042153.1\|WP_000746679.1\|466646_467273_-\|NDxxF-motif-lipoprotein	gnl\|CDD\|380196	NF033193, lipo_NDxxF, NDxxF motif lipoprotein. Members of this family are lipoproteins, about 200 amino acids long in precursor form, found in Staphylococcus aureus, Bacillus cereus, and various other Firmicutes. The protein family is named for one of its several highly conserved motifs.	1.15385e-71
NZ_CP042153.1\|WP_000956137.1\|473517_474474_-\|hypothetical-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00265416
NZ_CP042153.1\|WP_000052781.1\|469255_469825_-\|peroxiredoxin	gnl\|CDD\|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	1.50623e-124
NZ_CP042153.1\|WP_000930514.1\|467716_469240_-\|alkyl-hydroperoxide-reductase-subunit-F	gnl\|CDD\|237942	PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.	0
NZ_CP042153.1\|WP_114306602.1\|479691_481233_+\|glutamine-hydrolyzing-GMP-synthase	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
NZ_CP042153.1\|WP_000159787.1\|483376_483649_-\|transposase	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.23077e-11
NZ_CP042153.1\|WP_000763767.1\|475396_475804_-\|hypothetical-protein	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	2.17298e-12
NZ_CP042153.1\|WP_001287097.1\|470316_471072_+\|oxygen-insensitive-NADPH-nitroreductase	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	1.86866e-86
NZ_CP042153.1\|WP_000991014.1\|471151_472540_-\|L-cystine-transporter	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
NZ_CP042153.1\|WP_000793023.1\|476894_478163_+\|purine-permease	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	5.74823e-170
NZ_CP042153.1\|WP_000264071.1\|478200_479667_+\|IMP-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
NZ_CP042153.1\|WP_000421410.1\|476316_476895_+\|xanthine-phosphoribosyltransferase	gnl\|CDD\|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	9.01486e-119

>NZ_CP042153.1|WP_071621345.1|472933_473191_-|hypothetical-protein
MLVNDESHKGTLIFTFTTNAFFLKQKYLFTVAFELPPAHTNPQKMLILIRQNFLQRVCSKRLFKVDHLLSFYSINMRLAIFIKPS
>NZ_CP042153.1|WP_001792089.1|472624_472723_+|hypothetical-protein
MQLNVNMMKFDRWHKGICKQIVLNLVEKGEKG
>NZ_CP042153.1|WP_000991014.1|471151_472540_-|L-cystine-transporter
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLVYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQAHGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFESNDNAALTSH
>NZ_CP042153.1|WP_001287097.1|470316_471072_+|oxygen-insensitive-NADPH-nitroreductase
MSDYVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPHLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
>NZ_CP042153.1|WP_000052781.1|469255_469825_-|peroxiredoxin
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
>NZ_CP042153.1|WP_000930514.1|467716_469240_-|alkyl-hydroperoxide-reductase-subunit-F
MLNADLKQQLKQLLELMEGNVEFVASLGSDEKSKELKELLTEISDMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKNLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREESENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDIDAMTGIRATDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMSTGEEHLLNLDGIFVQIGLLPNTSWLKDAVELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
>NZ_CP042153.1|WP_000746679.1|466646_467273_-|NDxxF-motif-lipoprotein
MKKRLLLSTFLASALILTGCASDQSDNEDHHTSTGIHAPKSAKKLETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTEKQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDIEKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK
>NZ_CP042153.1|WP_000868256.1|465993_466377_-|hypothetical-protein
MKVRITFIILAILSTIVCLFLAAMHPTGPNTVTFEQPYLFTLNIILMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSLTQFTPFTLASFITSIILFISAIITLAIGGKSVDKNDSH
>NZ_CP042153.1|WP_000158375.1|465346_465928_+|histidine-phosphatase-family-protein
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAHQVVIRCLMVYFNKVSREEAVDLKVENCKPYIIE
>NZ_CP042153.1|WP_000211677.1|464959_465169_-|hypothetical-protein
MTTQSFIFMNIILLDGATQRHPFFICQILAFLFPKFPHINLLLFYPILSTFSNIIIHIDHFHANKKDDN
>NZ_CP042153.1|WP_000956137.1|473517_474474_-|hypothetical-protein
MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDFKEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVEDLRLEIQKMREERHLLGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQEAQASQAKVLAESTNKVEKNAVTEDKADSKDSKVAGVNTSTDAKTDTKAENAGDGTATKVDKEDQISATEAIEKASVEQSKNENAAETSNKEATVDADAQHDAEQQVAEAHAEASKQATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL
>NZ_CP042153.1|WP_000394698.1|474591_475254_-|hypothetical-protein
MEFKTIQSVKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNKTENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHELNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHPTNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRKPF
>NZ_CP042153.1|WP_000763767.1|475396_475804_-|hypothetical-protein
MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAVRDKSSHKEVQEHNSAYEEIDITHFAEASKGPKA
>NZ_CP042153.1|WP_000421410.1|476316_476895_+|xanthine-phosphoribosyltransferase
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
>NZ_CP042153.1|WP_000793023.1|476894_478163_+|purine-permease
MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVIIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTLIIILVLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGFSFDVTSTLVFFIVAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLLICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAISAIILNFFFNGIKYKQTEENVK
>NZ_CP042153.1|WP_000264071.1|478200_479667_+|IMP-dehydrogenase
MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
>NZ_CP042153.1|WP_114306602.1|479691_481233_+|glutamine-hydrolyzing-GMP-synthase
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCKGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPTNTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
>NZ_CP042153.1|WP_000551643.1|481345_481882_-|hypothetical-protein
MHNKNEFNKKLKDFIGSDKRMALVKGYINEYKLTTVLRALNNSDYTKGTIHTRSIGNLKQIVDNRIIPKNITQNKIFKLSNLTLEVNLYERNTIYHGDFAIYYPVESALIIETDTPRLINHINNNPVQKIFIITTNDWSFNTLELEKIVDETIIYDLKQEDPKQYEILYKNKHGKLPY
>NZ_CP042153.1|WP_000041880.1|482273_482978_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MSKNINQANSKLNTSNKKLKQAYSKSDSKNMKVIYMPHWLEFYSIAIHSDVTSNKKRYYKSFSRGTVVYVKLGSNIGSEFSGNHFCVILDNKDNKGKETVTIVPLSSKGNKNYLKLNESVLNLTATDLKKQIIDISSKVQALTQKYRDIDIKLSTEDKKLLSNLNQKANELYRVIGVYSKHKGKDTYVNISAITTISKRRISKINDSDPTGTIIISEDDMNEIEKQLKIKFFSN
>NZ_CP042153.1|WP_000159787.1|483376_483649_-|transposase
MTKERRTFSSEFKLQMVRLYKNGKLKNEIIRKYDLKPSIISNSIKQHQNTGPFNHQDNLKSDEKELIKLRKEVQHLKMEHDVLKQILKLI

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP042153_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042153_2

597459-597589

Orphan

Consensus_repeat	Method
GAGGTCGGTGGTTCGAGTCCACTTAGGCCCACCATTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042153_2

>merge|NZ_CP042153|2|597459-597589|CRISPRCasFinder
GAGGTCGGTGGTTCGAGTCCACTTAGGCCCACCATTAATTTAATACCTATTTGGGGGCTTAGCTCAGCTGGGAGAGCGCCTGCTTTGCACGCAGGAGGTCGGCGGTTCGAGTCCACTTAGGCCCACCATTA

>NZ_CP042153|2|2|597459-597589|CRISPRCasFinder
GAGGTCGGTGGTTCGAGTCCACTTAGGCCCACCATTA	ATTTAATACCTATTTGGGGGCTTAGCTCAGCTGGGAGAGCGCCTGCTTTGCACGCAG
GAGGTCGGCGGTTCGAGTCCACTTAGGCCCACCATTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042153.1\|WP_001154302.1\|591376_591742_+\|dihydroneopterin-aldolase	unknown	unknown	gnl\|CDD\|238298
NZ_CP042153.1\|WP_000547794.1\|604530_605745_-\|NupC/NupG-family-nucleoside-CNT-transporter	unknown	unknown	gnl\|CDD\|224883
NZ_CP042153.1\|WP_001790128.1\|592608_592701_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_001802965.1\|612307_613363_+\|PIN/TRAM-domain-containing-protein	unknown	unknown	gnl\|CDD\|227292
NZ_CP042153.1\|WP_000149502.1\|606938_607946_+\|protein-arginine-kinase	unknown	unknown	gnl\|CDD\|226387
NZ_CP042153.1\|WP_001176709.1\|583970_585266_+\|tRNA-lysidine(34)-synthetase-TilS	unknown	unknown	gnl\|CDD\|366502
NZ_CP042153.1\|WP_001167888.1\|586066_588160_+\|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	unknown	unknown	gnl\|CDD\|273520
NZ_CP042153.1\|WP_000551283.1\|585270_585810_+\|hypoxanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|223707
NZ_CP042153.1\|WP_000690439.1\|603762_604323_+\|pyridoxal-5'-phosphate-synthase-glutaminase-subunit-PdxT	unknown	unknown	gnl\|CDD\|237411
NZ_CP042153.1\|WP_000613722.1\|591738_592215_+\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	unknown	unknown	gnl\|CDD\|223872
NZ_CP042153.1\|WP_000882068.1\|606382_606949_+\|excinuclease-ABC-subunit-B	unknown	unknown	gnl\|CDD\|226397
NZ_CP042153.1\|WP_000551762.1\|605902_606364_+\|CtsR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226869
NZ_CP042153.1\|WP_000897132.1\|607959_610416_+\|ATP-dependent-Clp-protease-ATP-binding-subunit	unknown	unknown	gnl\|CDD\|223616
NZ_CP042153.1\|WP_001288202.1\|592753_594241_+\|lysine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234778
NZ_CP042153.1\|WP_000034728.1\|602871_603759_+\|pyridoxal-5'-phosphate-synthase-lyase-subunit-PdxS	unknown	unknown	gnl\|CDD\|179769
NZ_CP042153.1\|WP_000148605.1\|588387_589269_+\|Hsp33-family-molecular-chaperone-HslO	unknown	unknown	gnl\|CDD\|234643
NZ_CP042153.1\|WP_000167944.1\|590595_591399_+\|dihydropteroate-synthase	unknown	unknown	gnl\|CDD\|238380
NZ_CP042153.1\|WP_000057594.1\|589447_590380_+\|cysteine-synthase-A	unknown	unknown	gnl\|CDD\|273463
NZ_CP042153.1\|WP_001085219.1\|610900_612265_+\|DNA-repair-protein-RadA	unknown	unknown	gnl\|CDD\|236994
NZ_CP042153.1\|WP_000789919.1\|601385_602768_-\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089

Protein	Function_ID	Function_description	E-value
NZ_CP042153.1\|WP_001154302.1\|591376_591742_+\|dihydroneopterin-aldolase	gnl\|CDD\|238298	cd00534, DHNA_DHNTPE, Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is DHNA which catalyses the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin in the biosynthetic pathway of tetrahydrofolate. Though it is known that DHNTPE catalyzes the epimerization of dihydroneopterin triphosphate to dihydromonapterin triphosphate, the biological role of this enzyme is still unclear. It is hypothesized that it is not an essential protein since a folX knockout in E. coli has a normal phenotype and the fact that folX is not present in H. influenza. In addition both enzymes have been shown to be able to compensate for the other's activity albeit at slower reaction rates. The functional enzyme for both is an octamer of identical subunits. Mammals lack many of the enzymes in the folate pathway including, DHNA and DHNTPE.	1.74147e-48
NZ_CP042153.1\|WP_000547794.1\|604530_605745_-\|NupC/NupG-family-nucleoside-CNT-transporter	gnl\|CDD\|224883	COG1972, NupC, Nucleoside permease [Nucleotide transport and metabolism].	1.07791e-164
NZ_CP042153.1\|WP_001802965.1\|612307_613363_+\|PIN/TRAM-domain-containing-protein	gnl\|CDD\|227292	COG4956, COG4956, Integral membrane protein (PIN domain superfamily) [General function prediction only].	6.07116e-176
NZ_CP042153.1\|WP_000149502.1\|606938_607946_+\|protein-arginine-kinase	gnl\|CDD\|226387	COG3869, COG3869, Arginine kinase [Amino acid transport and metabolism].	1.27115e-169
NZ_CP042153.1\|WP_001176709.1\|583970_585266_+\|tRNA-lysidine(34)-synthetase-TilS	gnl\|CDD\|366502	pfam01171, ATP_bind_3, PP-loop family. This family of proteins belongs to the PP-loop superfamily.	8.42453e-77
NZ_CP042153.1\|WP_001167888.1\|586066_588160_+\|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	gnl\|CDD\|273520	TIGR01241, ATP-dependent_zinc_metalloprotease_FtsH, ATP-dependent metalloprotease FtsH. HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_CP042153.1\|WP_000551283.1\|585270_585810_+\|hypoxanthine-phosphoribosyltransferase	gnl\|CDD\|223707	COG0634, Hpt, Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism].	4.50006e-94
NZ_CP042153.1\|WP_000690439.1\|603762_604323_+\|pyridoxal-5'-phosphate-synthase-glutaminase-subunit-PdxT	gnl\|CDD\|237411	PRK13525, PRK13525, pyridoxal 5'-phosphate synthase glutaminase subunit PdxT.	9.71225e-112
NZ_CP042153.1\|WP_000613722.1\|591738_592215_+\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	gnl\|CDD\|223872	COG0801, FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase [Coenzyme metabolism].	3.49208e-73
NZ_CP042153.1\|WP_000882068.1\|606382_606949_+\|excinuclease-ABC-subunit-B	gnl\|CDD\|226397	COG3880, COG3880, Modulator of heat shock repressor CtsR, McsA [Signal transduction mechanisms].	1.31135e-64
NZ_CP042153.1\|WP_000551762.1\|605902_606364_+\|CtsR-family-transcriptional-regulator	gnl\|CDD\|226869	COG4463, CtsR, Transcriptional repressor of class III stress genes [Transcription].	1.64343e-81
NZ_CP042153.1\|WP_000897132.1\|607959_610416_+\|ATP-dependent-Clp-protease-ATP-binding-subunit	gnl\|CDD\|223616	COG0542, clpA, ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP042153.1\|WP_001288202.1\|592753_594241_+\|lysine--tRNA-ligase	gnl\|CDD\|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0
NZ_CP042153.1\|WP_000034728.1\|602871_603759_+\|pyridoxal-5'-phosphate-synthase-lyase-subunit-PdxS	gnl\|CDD\|179769	PRK04180, PRK04180, pyridoxal 5'-phosphate synthase lyase subunit PdxS.	0
NZ_CP042153.1\|WP_000148605.1\|588387_589269_+\|Hsp33-family-molecular-chaperone-HslO	gnl\|CDD\|234643	PRK00114, hslO, Hsp33 family molecular chaperone HslO.	1.83673e-160
NZ_CP042153.1\|WP_000167944.1\|590595_591399_+\|dihydropteroate-synthase	gnl\|CDD\|238380	cd00739, DHPS, DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and protein biosynthesis. Prokaryotes (and some lower eukaryotes) must synthesize folate de novo, while higher eukaryotes are able to utilize dietary folate and therefore lack DHPS. Sulfonamide drugs, which are substrate analogs of pABA, target DHPS.	9.15674e-121
NZ_CP042153.1\|WP_000057594.1\|589447_590380_+\|cysteine-synthase-A	gnl\|CDD\|273463	TIGR01136, Cysteine_synthase, cysteine synthase. This model discriminates cysteine synthases (EC 2.5.1.47) (both CysK and CysM) from cystathionine beta-synthase, a protein found primarily in eukaryotes and carrying a C-terminal CBS domain lacking from this protein. Bacterial proteins lacking the CBS domain but otherwise showing resemblamnce to cystathionine beta-synthases and considerable phylogenetic distance from known cysteine synthases were excluded from the seed and score below the trusted cutoff. [Amino acid biosynthesis, Serine family].	7.54326e-168
NZ_CP042153.1\|WP_001085219.1\|610900_612265_+\|DNA-repair-protein-RadA	gnl\|CDD\|236994	PRK11823, PRK11823, DNA repair protein RadA; Provisional.	0
NZ_CP042153.1\|WP_000789919.1\|601385_602768_-\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	5.65505e-130

>NZ_CP042153.1|WP_001288202.1|592753_594241_+|lysine--tRNA-ligase
MSEEMNDQMLVRRQKLQELYDLGIDPFGSKFDRSGLSSDLKEEWDQYSKEELVEKEADSHVAIAGRLMTKRGKGKAGFAHVQDLAGQIQIYVRKDQVGDDEFDLWKNADLGDIVGVEGVMFKTNTGELSVKAKKFTLLTKSLRPLPDKFHGLQDIEQRYRQRYLDLITNEDSTRTFINRSKIIQEMRNYLNNKGFLEVETPMMHQIAGGAAARPFVTHHNALDATLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYHDIMDLTESMVRHIANEVLGSAKVQYNGETIDLESAWTRLHIVDAVKEATGVDFYEVKSDEEAKALAKEHGIEIKDTMKYGHILNEFFEQKVEETLIQPTFIYGHPTEISPLAKKNPEDPRFTDRFELFIVGREHANAFTELNDPIDQKGRFEAQLVEKAQGNDEAHEMDEDYIEALEYGMPPTGGLGIGIDRLVMLLTDSPSIRDVLLFPYMRQK
>NZ_CP042153.1|WP_001790128.1|592608_592701_+|hypothetical-protein
MVNDKVLETSKEMYVEQKCLIFYKTLKENV
>NZ_CP042153.1|WP_000613722.1|591738_592215_+|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase
MIQAYLGLGSNIGDRESQLNDAIKILNEYDGISVSNISPIYETAPVGYTEQPNFLNLCVEIQTTLTVLQLLECCLKTEECLHRIRKERWGPRTLDVDILLYGEEMIDLPKLSVPHPRMNERAFVLIPLNDIAANVVEPRSKLKVKDLVFVDDSVKRYK
>NZ_CP042153.1|WP_001154302.1|591376_591742_+|dihydroneopterin-aldolase
MQDTIFLKGMRFYGYHGALSAENEIGQIFKVDVTLKVDLAEAGRTDNVIDTVHYGEVFEEVKSIMEGKAVNLLEHLAERIANRINSQYNRVMETKVRITKENPPIPGHYDGVGIEIVRENK
>NZ_CP042153.1|WP_000167944.1|590595_591399_+|dihydropteroate-synthase
MTKTKIMGILNVTPDSFSDGGKFNNVETAINRVKAMIDEGADIIDVGGVSTRPGHEMVTLEEELNRVLPVVEAIVGFDVKISVDTFRSEVAEACLKLGVDMINDQWAGLYDHRMFQIVAKYDAEIILMHNGNGNRDEPVVEEMLTSLLAQAHQAKIAGIPSNKIWLDPGIGFAKTRNEEAEVMARLDELVATEYPVLLATSRKRFTKEMMGYDTTPVERDEVTAATTAYGIMKGVRAVRVHNVELNAKLAKGIDFLKENENARHNLS
>NZ_CP042153.1|WP_000057594.1|589447_590380_+|cysteine-synthase-A
MAQKPVDNITQIIGGTPVVKLRNVVDDNAADVYVKLEYQNPGGSVKDRIALAMIEKAEREGKIKPGDTIVEPTSGNTGIGLAFVCAAKGYKAVFTMPETMSQERRNLLKAYGAELVLTPGSEAMKGAIKKAKELKEEHGYFEPQQFENPANPEVHELTTGPELLQQFEGKTIDAFLAGVGTGGTLSGVGKVLKKEYPNIEIVAIEPEASPVLSGGEPGPHKLQGLGAGFIPGTLNTEIYDSIIKVGNDTAMEMSRRVAKEEGILAGISSGAAIYAAIQKAKELGKGKTVVTVLPSNGERYLSTPLYSFDD
>NZ_CP042153.1|WP_000148605.1|588387_589269_+|Hsp33-family-molecular-chaperone-HslO
MTHDYIVKALAFDGEIRAYAALTTETVQEAQTRHYTWPTASAAMGRTMTATAMMGAMLKGDQKLTVTVDGQGPIGRIIADANAKGEVRAYVDHPQTHFPLNEQGKLDVRRAVGTNGSIMVVKDVGMKDYFSGASPIVSGELGEDFTYYYATSEQTPSSVGLGVLVNPDNTIKAAGGFIIQVMPGAKDETISKLEKAISEMTPVSKLIEQGLTPEGLLNEILGEDHVQILEKMPVQFECNCSHEKFLNAIKGLGEAEIQNMIKEDHGAEAVCHFCGNKYKYTEEELNVLLESLA
>NZ_CP042153.1|WP_001167888.1|586066_588160_+|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein
MQKAFRNVLVIVIIGVIIFGLFSYLNGNGNMPKQLTYNQFTEKLEKGDLKTLEIQPQQNVYMVSGKTKNDEDYSSTILYNNEKELQKITDAAKKQNGVKLTIKEEEKQSVFVSILSTLIPVVVIALLFIFFLSQAQGGGSGGRMMNFGKSKAKMYDNNKRRVRFSDVAGADEEKQELIEIVDFLKDNKKFKEMGSRIPKGVLLVGPPGTGKTLLARAVAGEAGAPFFSISGSDFVEMFVGVGASRVRDLFDNAKKNAPCIIFIDEIDAVGRQRGAGVGGGHDEREQTLNQLLVEMDGFGENEGIIMIAATNRPDILDPALLRPGRFDRQIQVGRPDVKGREAILHVHAKNKPLDETVDLKAISQRTPGFSGADLENLLNEASLIAVREGKKKIDMRDIEEATDRVIAGPAKKSRVISKKERNIVAHHEAGHTIIGMVLDEAEVVHKVTIVPRGQAGGYAMMLPKQDRFLMTEQELLDKICGLLGGRVSEDINFNEVSTGASNDFERATQIARSMVTQYGMSKKLGPLQFGHSNGQVFLGKDMQGEPNYSSQIAYEIDKEVQRIVKEQYERCKQILLEHKEQLILIAETLLTEETLVAEQIQSLFYEGKLPEIDYDAAKVVKDEDSEFNDGKFGKSYEEIRKEQLEDGQRDESEDRKEEKDIAEDKKEADKSDEKDEPAHRQAPNIEKPYDPNHPDNK
>NZ_CP042153.1|WP_000551283.1|585270_585810_+|hypoxanthine-phosphoribosyltransferase
MHNDLKEVLLTEEDIQNICKELGAQLTKDYQGKPLVCVGILKGSAMFMSDLIKRIDTHLSIDFMDVSSYHGGTESTGEVQIIKDLGSSIENKDVLIIEDILETGTTLKSITELLQSRKVNSLEIVTLLDKPNRRKADIEAKYVGKKIPDEFVVGYGLDYRELYRNLPYIGTLKPEVYSN
>NZ_CP042153.1|WP_001176709.1|583970_585266_+|tRNA-lysidine(34)-synthetase-TilS
MQLNSNGWHVDDHIVVAVSTGIDSMCLLYQLLNDYKDSYRKLTCLHVNHGVRSASIEEARFLEAYCERHHIDLHIKKLDLSHSLDRNNSIQNEARIKRYEWFDEMMNVLEADVLLTAHHLDDQLETIMYRIFNGKSTRNKLGFDELSKRKGYQIYRPLLAVSKKEIKQFQERYHIPYFEDESNKDNKYIRNDIRNRIIPAIDENNQLKVSHLLKLKQWHDEQYDILQYSAKQFIQEFVKFDEQSKYLEVSRQAFNNLPNSLKMVVLDCLLSKYYELFNISAKTYEEWFKQFSSKKAQFSINLTDKWIIQIAYGKLIIMAKNNGDTYFRVQTIKKPGNYFFNKYRLEIHSNLPKCLFPLTVRTRQSGDTFKLNGRDGYKKVNRLFIDCKVPQWVRDQMPIVLDKQQRIIAVGDLYQQQTIKKWIIISKNGDE
>NZ_CP042153.1|WP_000789919.1|601385_602768_-|PLP-dependent-aminotransferase-family-protein
MKNILYHQLYEKLKKQIIEGQFKEGDKFYSKRQLSKHLSISQTTVEHAYQLLLDEGYIYSRPRSGYFVSEIESLTILNNQPIPSLFDDDSYKPKASDEAYDYAFNLDEIDTKHFPIELFRKYSKDLYDTNHLNQLRRGHFQGELHLRFQLAFYLFTNRGVICDPNQIIIGSSTEQLVNQLVDLLYTSTFIIEKPSYPPIKNILDKKQVEYEQIEVEDNGINVDEVIKSQKNIVYITPSHQFPTGYVMDLKKRTQLIQWAQEKEERFIIEDDYDSEFRYFGKPIPAIQGLYSRGEKVIYISTFSKSIFPSCRVAYMVLPYSIMKKYHSQNHIEGNTVPVHMQNLIATFISSGGFERHLNKMRRIYRRKLTYILKRLKPYKEQLDIQGAETGMHFTITVKNGLTLQECLDRANKVKLKLQVYNFDDDQDYKKTPKFILGFGGIDDDALKPHVDALIKSLIIK
>NZ_CP042153.1|WP_000034728.1|602871_603759_+|pyridoxal-5'-phosphate-synthase-lyase-subunit-PdxS
MSKIIGSDRVKRGMAEMQKGGVIMDVVNAEQARIAEEAGAVAVMALERVPSDIRAAGGVARMANPKIVEEVMNAVSIPVMAKARIGHITEARVLEAMGVDYIDESEVLTPADEEYHLRKDQFTVPFVCGCRNLGEAARRIGEGAAMLRTKGEPGTGNIVEAVRHMRQVNSEVSRLTVMNDDEIMTFAKDIGAPYEILKQIKDNGRLPVVNFAAGGVATPQDAALMMELGADGVFVGSGIFKSEDPEKFAKAIVQATTHYQDYELIGRLASELGTAMKGLDINQLSLEERMQERGW
>NZ_CP042153.1|WP_000690439.1|603762_604323_+|pyridoxal-5'-phosphate-synthase-glutaminase-subunit-PdxT
MKIGVLALQGAVREHIRHIELSGHEGIAVKKVEQLEEIEGLILPGGESTTLRRLMNLYGFKEALQNSTLPMFGTCAGLIVLAQDIVGEEGYLNKLNITVQRNSFGRQVDSFETELDIKGIATDIEGVFIRAPHIEKVGQGVDILCKVNEKIVAVQQGKYLGVSFHPELTDDYRVTDYFINHIVKKA
>NZ_CP042153.1|WP_000547794.1|604530_605745_-|NupC/NupG-family-nucleoside-CNT-transporter
MHILIGIIGIIFFLALAFLFSSDRKNIRWKYVGILLAIQLIFAFILLKTTMGIKVIGGISNGFNYLLLKAADGVNFVFGGIQYIDPKQPPFFFSVLLPIVFISAIIGILQYTKILPLIINVLGFLISKINGMGRLESYNAVAAAILGQSEVFISIKKQLPYIPKQRLYTLTASAMSTVSASIIGAYFTLIEPKYVVTAVVLNLFGGFIIASIINPYKVNEEDDKLLVEETEERQQSFFEMLGEYILDGFKVAVIVGAMLIGYIAIIALLNGIVSNIFSTVSGGAISWDFQTLIGFVFAPFAFLVGVPWQDAVQAGSVMATKLLSNEFVAMQALGKLSDLSEHAKGVTSVFLVSFANFSSIGIISGAIKSLNDKKGDTVARFGLKLLFGATLVSFISAAIAGFFI
>NZ_CP042153.1|WP_000551762.1|605902_606364_+|CtsR-family-transcriptional-regulator
MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYIIDGLLDKMLINEREAKMIQAVIDRETLSMDMVSRDIIRANILKRLLPVINYY
>NZ_CP042153.1|WP_000882068.1|606382_606949_+|excinuclease-ABC-subunit-B
MLCENCQLNEAELKVKVTSKNKTEEKMVCQTCAEGHHPWNQANEQPEYQEHQDNFEEAFVVKQILQHLATKHGINFQEVAFKEEKRCPSCHMTLKDIAHVGKFGCANCYATFKDDIIDIVRRVQGGQFEHGGKTPHSSHKKIALKRKIEEKNEYLKKLIEIQDFEEAAIVRDEIKALKAESEVQHDDA
>NZ_CP042153.1|WP_000149502.1|606938_607946_+|protein-arginine-kinase
MTHNIHDNISQWMKSNEETPIVMSSRIRLARNLENHVHPLMYATENDGFRVINEVQDALPNFELMRLDQMDQQSKMKMVAKHLISPELIKQPAAAVLVNDDESLSVMINEEDHIRIQAMGTDTTLQALYNQASSIDDELDRSLDISYDEQLGYLTTCPTNIGTGMRASVMLHLPGLSIMKRMTRIAQTINRFGYTIRGIYGEGSQVYGHTYQVSNQLTLGKSELEIIETLTEVVNQIIHDEKQIRQKLDTYNQLETQDRVFRSLGILQNCRMITMEEASYRLSEVKLGIDLNYIELQNFKFNELMVAIQSPFLLDEEDDKSVKEKRADILREHIK
>NZ_CP042153.1|WP_000897132.1|607959_610416_+|ATP-dependent-Clp-protease-ATP-binding-subunit
MLFGRLTERAQRVLAHAQEEAIRLNHSNIGTEHLLLGLMKEPEGIAAKVLESFNITEDKVIEEVEKLIGHGQDHVGTLHYTPRAKKVIELSMDEARKLHHNFVGTEHILLGLIRENEGVAARVFANLDLNITKARAQVVKALGNPEMSNKNAQASKSNNTPTLDSLARDLTVIAKDGTLDPVIGRDKEITRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQAIVNNEVPETLKDKRVMSLDMGTVVAGTKYRGEFEERLKKVMEEIQQAGNVILFIDELHTLVGAGGAEGAIDASNILKPALARGELQCIGATTLDEYRKNIEKDAALERRFQPVQVDEPSVVDTVAILKGLRDRYEAHHRINISDEAIEAAVKLSNRYVSDRFLPDKAIDLIDEASSKVRLKSHTTPNNLKEIEQEIEKVKNEKDAAVHAQEFENAANLRDKQTKLEKQYEEAKNEWKNAQNGMSTSLSEEDIAEVIAGWTGIPLTKINETESEKLLSLEDTLHERVIGQKDAVNSISKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAESMFGDDDAMIRVDMSEFMEKHAVSRLVGAPPGYVGHDDGGQLTEKVRRKPYSVILFDEIEKAHPDVFNILLQVLDDGHLTDTKGRTVDFRNTIIIMTSNVGAQELQDQRFAGFGGSSDGQDYETIRKTMLKELKNSFRPEFLNRVDDIIVFHKLTKEELKEIVTMMVNKLTNRLSEQNINIIVTDKAKDKIAEEGYDPEYGARPLIRAIQKTIEDNLSELILDGNQIEGKKVTVDHDGKEFKYDIAEQTSETKTPSQA
>NZ_CP042153.1|WP_001085219.1|610900_612265_+|DNA-repair-protein-RadA
MAKKKVIFECMACGYQSPKWMGKCPNCGAWNQMEEIVEKAANPKHGVKTKELAGKVQKLNSIKHETTPRVLTDSAEFNRVLGGGIVSGSLVLIGGDPGIGKSTLLLQICASLSQKKKVLYITGEESLSQTKLRAERLDEDSSELQVLAETDLEVIYQTVKEEQPDLLVVDSIQTIYHPEISSAPGSVSQVRESTQSLMNIAKQMNIATFIVGHVTKEGQIAGPRLLEHMVDTVLYFEGDEHHAYRILRAVKNRFGSTNEMGIFEMKQSGLKGVNNPSEMFLEERSTNVPGSTIVATMEGTRPLLIEVQALVTPTTFNNPRRMATGIDHNRLSLLMAVLEKKENYLLQQQDAYIKVAGGVKLTEPAVDLSVIVATASSFKDKAVDGLDCYIGEVGLTGEVRRVSRIEQRVQEAAKLGFKRVIIPKNNIGGWTYPEGIQVIGVTTVHEALSFALHS
>NZ_CP042153.1|WP_001802965.1|612307_613363_+|PIN/TRAM-domain-containing-protein
MVIIIYLIIGSALGIIIIPEIANDLGLQNSSFLKNHYVDGIIGSIFMFLIFGVFIRRVTNAIKGLEHFIMRRSAVEILFATIGLIIGLLISVMVSFILESIGNSIFNHFIPVIITILLCYFGFQFGLKKRDEMLMFLPENIARSMSQHTKSATPKIIDTSAIIDGRILEVIRCGFIDGNILIPQGVINELQIVADSNDSVKREKGKRGLDILNELYDLDYPTKVIHPTKTHSDIDTMLLKLAKQYHASIITTDFNLNKVCHVHGIKALNVNDLSEAIKPNVHQGDQLHILLTKMGKEPGQAVGYLDDGTMVVVDNAKNLIGSHVNLEVVSLLQTSSGRIVFAKKIEDTVSL

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Crispr_ID: NZ_CP042153_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042153_3

820601-820683

Orphan

Consensus_repeat	Method
CCAATTTCTACAGACAATGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042153_3

>merge|NZ_CP042153|3|820601-820683|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACATAGAGAAATTGGAACGCCAATTTCTACAGACAATGCAAGTTGG

>NZ_CP042153|3|3|820601-820683|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGG	CGGGGCCCCAACATAGAGAAATTGGAACG
CCAATTTCTACAGACAATGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042153.1\|WP_000022323.1\|808202_809207_+\|biotin-dependent-carboxyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224895
NZ_CP042153.1\|WP_000180991.1\|816758_818273_+\|ABC-transporter-permease/substrate-binding-protein	unknown	unknown	gnl\|CDD\|270328
NZ_CP042153.1\|WP_000197262.1\|819909_820452_+\|5'-3'-deoxyribonucleotidase	unknown	unknown	gnl\|CDD\|226895
NZ_CP042153.1\|WP_025174185.1\|820894_821062_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000983677.1\|813785_815567_+\|DNA-helicase-RecQ	unknown	unknown	gnl\|CDD\|273594
NZ_CP042153.1\|WP_000193751.1\|822517_824023_-\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|225646
NZ_CP042153.1\|WP_000525106.1\|811890_813774_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_CP042153.1\|WP_001790091.1\|826136_826403_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000098285.1\|809680_811621_+\|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS	unknown	unknown	gnl\|CDD\|224287
NZ_CP042153.1\|WP_000589248.1\|815788_816766_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224050
NZ_CP042153.1\|WP_000708689.1\|807508_808219_+\|allophanate-hydrolase-subunit-1	unknown	unknown	gnl\|CDD\|224960
NZ_CP042153.1\|WP_000663030.1\|818512_819571_+\|histidinol-phosphate-transaminase	unknown	unknown	gnl\|CDD\|235106
NZ_CP042153.1\|WP_031760357.1\|822338_822440_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000692521.1\|826552_826951_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	unknown	unknown	gnl\|CDD\|224694
NZ_CP042153.1\|WP_000562498.1\|829136_830108_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|275027
NZ_CP042153.1\|WP_001068501.1\|824885_825752_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769
NZ_CP042153.1\|WP_000930018.1\|824365_824866_-\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	unknown	unknown	gnl\|CDD\|223851
NZ_CP042153.1\|WP_000429006.1\|821330_822248_-\|diacylglycerol-kinase-family-lipid-kinase	unknown	unknown	gnl\|CDD\|224513
NZ_CP042153.1\|WP_000855519.1\|826913_829019_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|236069
NZ_CP042153.1\|WP_001797134.1\|807214_807421_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP042153.1\|WP_000022323.1\|808202_809207_+\|biotin-dependent-carboxyltransferase-family-protein	gnl\|CDD\|224895	COG1984, DUR1, Allophanate hydrolase subunit 2 [Amino acid transport and metabolism].	1.25641e-144
NZ_CP042153.1\|WP_000180991.1\|816758_818273_+\|ABC-transporter-permease/substrate-binding-protein	gnl\|CDD\|270328	cd13610, PBP2_ChoS, Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.03165e-152
NZ_CP042153.1\|WP_000197262.1\|819909_820452_+\|5'-3'-deoxyribonucleotidase	gnl\|CDD\|226895	COG4502, COG4502, 5'(3')-deoxyribonucleotidase [Nucleotide transport and metabolism].	3.14113e-108
NZ_CP042153.1\|WP_000429006.1\|821330_822248_-\|diacylglycerol-kinase-family-lipid-kinase	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	7.55646e-79
NZ_CP042153.1\|WP_000983677.1\|813785_815567_+\|DNA-helicase-RecQ	gnl\|CDD\|273594	TIGR01389, recQ, ATP-dependent DNA helicase RecQ. The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions, as well as more distantly related bacterial helicases related to RecQ. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP042153.1\|WP_000193751.1\|822517_824023_-\|peptide-MFS-transporter	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	1.22605e-172
NZ_CP042153.1\|WP_000525106.1\|811890_813774_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NZ_CP042153.1\|WP_000855519.1\|826913_829019_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|236069	PRK07632, PRK07632, ribonucleotide-diphosphate reductase subunit alpha; Validated.	0
NZ_CP042153.1\|WP_000098285.1\|809680_811621_+\|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS	gnl\|CDD\|224287	COG1368, MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane].	0
NZ_CP042153.1\|WP_000589248.1\|815788_816766_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	1.28246e-155
NZ_CP042153.1\|WP_000708689.1\|807508_808219_+\|allophanate-hydrolase-subunit-1	gnl\|CDD\|224960	COG2049, DUR1, Allophanate hydrolase subunit 1 [Amino acid transport and metabolism].	7.79711e-94
NZ_CP042153.1\|WP_000663030.1\|818512_819571_+\|histidinol-phosphate-transaminase	gnl\|CDD\|235106	PRK03158, PRK03158, histidinol-phosphate aminotransferase; Provisional.	0
NZ_CP042153.1\|WP_000692521.1\|826552_826951_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	gnl\|CDD\|224694	COG1780, NrdI, Protein involved in ribonucleotide reduction [Nucleotide transport and metabolism].	5.52807e-56
NZ_CP042153.1\|WP_001068501.1\|824885_825752_-\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	3.04233e-10
NZ_CP042153.1\|WP_000562498.1\|829136_830108_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	gnl\|CDD\|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	2.30551e-164
NZ_CP042153.1\|WP_000930018.1\|824365_824866_-\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	gnl\|CDD\|223851	COG0780, COG0780, Enzyme related to GTP cyclohydrolase I [General function prediction only].	8.55989e-78

>NZ_CP042153.1|WP_000197262.1|819909_820452_+|5'-3'-deoxyribonucleotidase
MTRKSIAIDMDEVLADTLGEIIDAVNFRADLGIKMEALNGQKLKHVIPEHDGLITEVLREPGFFRHLKVMPHAQEVVKKLTEHYDVYIATAAMDVPTSFSDKYEWLLEFFPFLDPQHFVFCGRKNIVKADYLIDDNPRQLEIFTGTPIMFTAVHNINDDRFERVNSWKDVEQYFLDNIEK
>NZ_CP042153.1|WP_000663030.1|818512_819571_+|histidinol-phosphate-transaminase
MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKEVNEDTSLVWLCNPNNPTGTYFNHESLDSFLSQVPPHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAIEKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSEYFLPSQTNFIFVKTKRVNELYEALLNVGCITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE
>NZ_CP042153.1|WP_000180991.1|816758_818273_+|ABC-transporter-permease/substrate-binding-protein
MTNFFDILSERKGQLFSTMIEHIQISFIALLIATAIAVPLGILLTKTKTISEIVMNIAAILQTIPSLALLGLMIPLFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPFRRLTKVELPIAMPVIMAGVRTAMVLIIGTATLAALIGAGGLGDLILLGIDRNNASLILLGAIPAALLAIIFDLILRFMAKLSYKKLLMTLGVIVMIIILAIAIPMFAQKGDKITLAGKLGSEPSIITNMYKILIEEETKNTVEVKDGMGKTAFLFNALKSDDIDGYLEFTGTVLGELTKEPLKSKEEKKVYEQAKQSLEKKYQMTMLKPMKYNNTYALAVKRDFAKQHNIRTIGDLNKVKDQLKPGFTLEFNDRPDGYKAVQKAYNLNLDNIRTMEPKLRYQAINKGNINLIDAYSTDAELKQYDMVVLKDDKHVFPPYQGAPLFKESFLKKHPEIKKPLNKLENKISDEDMQMMNYKVTVKNEDPYTVAKDYLKAKGLIK
>NZ_CP042153.1|WP_000589248.1|815788_816766_+|ABC-transporter-ATP-binding-protein
MIKFKNVTKRYGKHVAVDNISFNINEGEFFVLIGPSGCGKTTTLKMINRLIHLSEGYIYFKDKPISDYPVYEMRWDIGYVLQQIALFPHMTIKENIAQVPQMKKWKEKDIDKRVDELLDMVGLEPEKYKNRKPDELSGGQRQRVGVIRALAADPPVILMDEPFSALDPISREKLQDDLIELQTKIKKTIIFVTHDIQEAMKLGDKICLLNEGHIEQIDTPEGFKNNPQSEFVKQFMGSHLEDDAPCVEENAIIRDLDIMKPIDEVTSMSAYPIVYDNQPIEVLYQHLSESERVIVMQEDSVGQYVIDRKDIFKYLSQKKEVAQHD
>NZ_CP042153.1|WP_000983677.1|813785_815567_+|DNA-helicase-RecQ
MMQQTLSHYFGYETFRPGQEEIISKVLDHRNVLGVLPTGGGKSICYQVPGLLLGGTTIVISPLISLMKDQVDQLKAMGIQAAFLNSSLTQKEQQRIEKALSNGEIQFLYVAPERFENRYFLNMLQRIKIHLVAFDEAHCISKWGHDFRPSYQNVISKVFTLPQDFTIIALTATATVEVQQDIREKLNIAQTDQIKTSTKRRNLIFKVNPTYQRQKFILDYIKTHDEDAGIIYCSTRKQVEELQEALESQKIESVIYHAGLSNKEREEAQNDFLFDRVKVVVATNAFGMGIDKSNVRFVIHYNMPGDLESYYQEAGRAGRDGLKSECILLFSERDINLHEYFITVSQADDDYKDKMGEKLTKMIQYTKTKKCLEATIVHYFEPNEKLEECEQCSNCVQQDKSYNMTQEAKMIISCIARMKQQESYSVIIQVLRGESTDYIKYKGYDQISTHGLMKGYTTSELSHLIDELRFKGFLNENDEILMCDTSIKKLLSNEVEVFTTPFKQKATEKVFINTVEGVDRVLFSQLVEVRKKLSDKLTIAPVSIFSDYTLEEFAKRKPASKQDMINIDGVGSYKLKHYCPAFLETIQNYKAKV
>NZ_CP042153.1|WP_000525106.1|811890_813774_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MGMEAYKIEHLNKSYADKTIFDNLDLSISEGEKIGLVGINGTGKSTLLKVIGGIDDDFTANVMHPNQYRIRYSSQKQDLNEDMTVFDAVLSSDTTTLRIIKQYEQAVQAYADDQSDKLFKRMIDAQDAMDQHDAWDYNAEIKTILSKLGIHDTTKYIKELSGGQQKRVVLAKTLIEQPDLLLLDEPTNHLDFESISWLINYVKQYPHTVLFVTHDRYFLNEVSTRIIELNRGKLASYPGNYESYIEMRAEREVTLQKQQQKQRALYKEELAWMRAGAKARTTKQQARINRFNDLENEVNQQYKDDKGELNLAYSRLGKQVFELEDLSKAINDKVLFEHLTEIIQKGERIGVVGPNGAGKTTLLNILSGEDQQFEGKLKTGQTVKVAYFKQTDETLDRDIRMIDYLREESEVAKEKDGTSVSITQLLERFLFPSATHGKKVYKLSGGEQKRLYLLRLLVHQPNVLLLDEPTNDLDTETLTILEDYIHTFGGTVITVSHDRYFLNKVAQSYWFIHDGQMEKIIGTFEDYESYKKSLDKNKSTLKQQSKSYTTVRKKNGLSYKEKLEYEQLMKRIEQAEVRMEEIDVLMIEASADYGKIKELNEEKEQLEIQYDLDITRWSELEEIKEQQ
>NZ_CP042153.1|WP_000098285.1|809680_811621_+|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS
MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEYYGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGISENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
>NZ_CP042153.1|WP_000022323.1|808202_809207_+|biotin-dependent-carboxyltransferase-family-protein
MSIIIEKSGLFSSFQDFGRRGYEHDGVIPCGALDTLAHEIANRLVANDKNEATLEMTNKMATIRFTEPTLIALAGGNVKAYTEHMTISPYKLYLLDKGDVLKFRETSYTSRVYLAVGGGFELDAWLGSNSTDFNVKIGGFKGRTLQDGDEIKLKRDYTARHHKLFENLAHTKQTDWGIDGYALSFNYMSDVFHVVKNKGTEDFKEDAIQRFVKHDYKVTSKANRMGMMLEGEKIKAFYEDMPPYQTVKKGTIQIKRDGTPIILLNDHYTLGSYPQIGTIASYHLTKLAQKPQGSRLKFQFIDILTAEKNLVKYSNWLNQLFHGIEYRMQLEMMK
>NZ_CP042153.1|WP_000708689.1|807508_808219_+|allophanate-hydrolase-subunit-1
MKIYSQGDQAIVVAIEKEVSKSLTEDLLTLRSYLIEQNYPFIIEIVPSESDMMIVYDARDMIKHHNIQSPFLYMKALIESIHLNIKHDFNQQDLIEIPIVYGSKYGPDIESLLKHYKIKLETFIELHSKTQYFVSMMGYSPGFPYLTGLNKKLYINHTSKQKKFIPAGSVVLEGKKCGIVTTDTINDWLVIGYTPLSLFNPKESDFARLKLGDNIKFRPINENELDVGAFKDVNHN
>NZ_CP042153.1|WP_001797134.1|807214_807421_+|hypothetical-protein
MIIVYIVLLLILVYVNYRLVNRLLSENRIYVVRLIVTITTVISFILVYALIHELMPFVVRAMDLMYHQ
>NZ_CP042153.1|WP_025174185.1|820894_821062_+|hypothetical-protein
MQVGVGRRNKFCENIISVPLPPIFKYTLALTNDKESLHNQSLVVLYHFRPALNKC
>NZ_CP042153.1|WP_000429006.1|821330_822248_-|diacylglycerol-kinase-family-lipid-kinase
MENKYTHGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKNYAKDVDILFILGGDGTVNELINGVMSHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSPQDGELNTFIFNEQSFSILNDIFKKRDSMNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLTVNDL
>NZ_CP042153.1|WP_031760357.1|822338_822440_+|hypothetical-protein
MVITDIDVYRVGRENIVIAVYNEHIKLLFILIS
>NZ_CP042153.1|WP_000193751.1|822517_824023_-|peptide-MFS-transporter
MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMRALLIFYMYFAVTDNGLGIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLGAVFIIIGHICLSLPFALIGLFTSMFFIIIGSGLMKPNISNIVGRLYPENDRRMDAGFVIFYMSVNMGALLSPIILQHFVNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMKPTNPLTPAEKKKYGLIIGSVVLAIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYFTLIIRSKDVTDTERSRVKAFIPLFILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGWKTNFGEAIFQSINPLFILLLAPIISLLWQKLGTKQPSLPVKFAIGTFLAGASYILIGIVGYASGSSNFSVNWVILSYIICVIGELCLSPTGNSAAVKLAPKAFNAQMMSIWYLTNASAQAINGTLVKLIEPLGQTNYFIFLGVVAIIVTTIVLAFSPLIIKAMKGIR
>NZ_CP042153.1|WP_000930018.1|824365_824866_-|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF
MAHGRQQDELQDITLLGNQDNTYNFDYRPDVLESFDNKHQGRDYFVKFNCPEFTSLCPITGQPDFATIYISYIPNVKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNNLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPNSKYEKMAEHRLMNHDLYPEKIDNR
>NZ_CP042153.1|WP_001068501.1|824885_825752_-|DMT-family-transporter
MNPKVKGIIAILISAIGFSFMSVFFRLAGDLPVFQKSLARNLVAMFIPLFFLYKYHQPMFGRLSSQPLLITRSTLGLIGVLLNIYAIDHMVLSDADSLMKLNPFWTILLSIVFLHEKVRKYQITAMIIAILGMLLIVKPEFSSSMIPSLAGLFSGIFAASAYTCVRALSSREAPYTIVFYFSLFSVIVLIPFTAYTYEPMSQMQILYLLGAGLAAAVGQIGVTLAYSFAAAKDISIFTYASIIFTAILGFVLFGESPDFYATLGYVVIIGASYYMFEKARRDAKIIKK
>NZ_CP042153.1|WP_001790091.1|826136_826403_+|hypothetical-protein
MCLMYNETHNIVLVKRKRHNILCFVCKCFIYEEITFKSNLTQKFNSYYQLIVIFLENVLSKWKISNDVNTTYSDFYTFNPYKLLFSQI
>NZ_CP042153.1|WP_000692521.1|826552_826951_+|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI
MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFELHGKNKDVIEFKNKVGNFNENHGREKVQSY
>NZ_CP042153.1|WP_000855519.1|826913_829019_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha
MKTMEEKKYNHIELNNEVTKRREDGFFSLEKDQEALVAYLEEVKDKTILFDTEIERLRYLVDNDFYFNVFDIYSEADLIEITDYAKSISFNFASYMSASKFFKDYALKTNDKSQYLEDYNQHVAIVALYLANGNKAQAKQFISAMVEQRYQPATPTFLNAGRARRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGIAKGVLPIAKSLEGGFSYADQLGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGLIVPSKFFDLAKEGKDFYMFAPHTVKEEYGVTLDDIDLEKYYDDMVANPNVEKKKKNAREMLNLIAQTQLQSGYPYLMFKDNANRVHPNSNIGQIKMSNLCTEIFQLQETSIINDYGIEDEIKRDISCNLGSLNIVNVMESGKFRDSVHSGMDALTVVSDVANIQNAPGVRKANSELHSVGLGVMNLHGYLAKNKIGYESEEAKDFANIFFMMMNFYSIERSMEIAKERGIKYQDFEKSDYANGKYFEFYTTQEFEPQFEKVRELFDGMAIPTSEDWKKLQQDVEQYGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPQTMWYYKSAFNTDQMKLIDLIATIQTHIDQGISTILYVNSEISTRELARLYVYAHYKGLKSLYYTRNKLLSVEECTSCSI
>NZ_CP042153.1|WP_000562498.1|829136_830108_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta
MIAVNWNTQEDMTNMFWRQNISQMWVETEFKVSKDIASWKTLSEAEQDTFKKALAGLTGLDTHQADDGMPLVMLHTTDLRKKAVYSFMAMMEQIHAKSYSHIFTTLLPSSETNYLLDEWVLEEPHLKYKSDKIVANYHKLWGKEASIYDQYMARVTSVFLETFLFFSGFYYPLYLAGQGKMTTSGEIIRKILLDESIHGVFTGLDAQHLRNELSESEKQKADQEMYKLLNDLYLNEESYTKMLYDDLGITEDVLNYVKYNGNKALSNLGFEPYFEEREFNPIIENALDTTTKNHDFFSVKGDGYVLALNVEALQDDDFVFDNK

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Crispr_ID: NZ_CP042153_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042153_4

861550-861628

Unclear

Consensus_repeat	Method
TGTAGAATTTCTTTTCGAAATTCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042153_4

>merge|NZ_CP042153|4|861550-861628|CRISPRCasFinder
TGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCCGCCAACTTGCATTGCCTGTAGAATTTCTTTTCGAAATTCT

>NZ_CP042153|4|4|861550-861628|CRISPRCasFinder
TGTAGAATTTCTTTTCGAAATTCT	CTGTGTTGGGGCCCCGCCAACTTGCATTGCC
TGTAGAATTTCTTTTCGAAATTCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042153.1\|WP_114306606.1\|871726_872629_-\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|224015
NZ_CP042153.1\|WP_001792175.1\|853963_854071_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000006551.1\|869388_870333_+\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NZ_CP042153.1\|WP_114306605.1\|858376_861223_+\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_CP042153.1\|WP_000134963.1\|865670_866606_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NZ_CP042153.1\|WP_000958224.1\|861886_862819_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
NZ_CP042153.1\|WP_000369730.1\|867374_868286_+\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|224574
NZ_CP042153.1\|WP_001790092.1\|852426_852531_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000506531.1\|849853_852385_+\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
NZ_CP042153.1\|WP_000057543.1\|864164_865604_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
NZ_CP042153.1\|WP_010956549.1\|852699_853810_+\|peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
NZ_CP042153.1\|WP_001248939.1\|868282_869278_+\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NZ_CP042153.1\|WP_000513305.1\|862824_863664_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
NZ_CP042153.1\|WP_145411579.1\|863671_864157_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_CP042153.1\|WP_001049165.1\|870896_871484_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
NZ_CP042153.1\|WP_000638419.1\|855878_856115_+\|CsbA-family-protein	unknown	unknown	gnl\|CDD\|227234
NZ_CP042153.1\|WP_000753318.1\|854218_855058_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP042153.1\|WP_000538141.1\|855231_855882_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|378993
NZ_CP042153.1\|WP_000617735.1\|848867_849440_+\|ribosome-associated-translation-inhibitor-RaiA	unknown	unknown	gnl\|CDD\|224461
NZ_CP042153.1\|WP_000229241.1\|856383_858369_+\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395

Protein	Function_ID	Function_description	E-value
NZ_CP042153.1\|WP_114306606.1\|871726_872629_-\|TIGR01777-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	3.56838e-154
NZ_CP042153.1\|WP_000506531.1\|849853_852385_+\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NZ_CP042153.1\|WP_000006551.1\|869388_870333_+\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
NZ_CP042153.1\|WP_000134963.1\|865670_866606_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
NZ_CP042153.1\|WP_000958224.1\|861886_862819_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
NZ_CP042153.1\|WP_000369730.1\|867374_868286_+\|RNase-adapter-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	5.38488e-169
NZ_CP042153.1\|WP_000617735.1\|848867_849440_+\|ribosome-associated-translation-inhibitor-RaiA	gnl\|CDD\|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	1.13584e-37
NZ_CP042153.1\|WP_000057543.1\|864164_865604_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.14043e-06
NZ_CP042153.1\|WP_114306605.1\|858376_861223_+\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_CP042153.1\|WP_001248939.1\|868282_869278_+\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
NZ_CP042153.1\|WP_000513305.1\|862824_863664_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.75588e-120
NZ_CP042153.1\|WP_001049165.1\|870896_871484_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
NZ_CP042153.1\|WP_000638419.1\|855878_856115_+\|CsbA-family-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
NZ_CP042153.1\|WP_145411579.1\|863671_864157_+\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.25079e-30
NZ_CP042153.1\|WP_000753318.1\|854218_855058_+\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	7.40441e-41
NZ_CP042153.1\|WP_000538141.1\|855231_855882_+\|HD-domain-containing-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
NZ_CP042153.1\|WP_010956549.1\|852699_853810_+\|peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
NZ_CP042153.1\|WP_000229241.1\|856383_858369_+\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0

>NZ_CP042153.1|WP_114306605.1|858376_861223_+|excinuclease-ABC-subunit-UvrA
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRCYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIDVPEYRRPASDRKISIRGARSNNLKGIDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>NZ_CP042153.1|WP_000229241.1|856383_858369_+|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIKEIVDGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>NZ_CP042153.1|WP_000638419.1|855878_856115_+|CsbA-family-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>NZ_CP042153.1|WP_000538141.1|855231_855882_+|HD-domain-containing-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>NZ_CP042153.1|WP_000753318.1|854218_855058_+|CHAP-domain-containing-protein
MKKTLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKSPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTLEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>NZ_CP042153.1|WP_001792175.1|853963_854071_+|hypothetical-protein
MCLLKQHMQCAFSNITYGDFQGIELIVENVLNYMV
>NZ_CP042153.1|WP_010956549.1|852699_853810_+|peptide-chain-release-factor-2
MELSEIKRNIDKYNQDLTQIRGSLDLENKETNIQEYEEMMAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
>NZ_CP042153.1|WP_001790092.1|852426_852531_+|hypothetical-protein
MLWEESFYFTSVKYFKKCEEVVKRCYVLSFKKSV
>NZ_CP042153.1|WP_000506531.1|849853_852385_+|preprotein-translocase-subunit-SecA
MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
>NZ_CP042153.1|WP_000617735.1|848867_849440_+|ribosome-associated-translation-inhibitor-RaiA
MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ
>NZ_CP042153.1|WP_000958224.1|861886_862819_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>NZ_CP042153.1|WP_000513305.1|862824_863664_+|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>NZ_CP042153.1|WP_145411579.1|863671_864157_+|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVEFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>NZ_CP042153.1|WP_000057543.1|864164_865604_+|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>NZ_CP042153.1|WP_000134963.1|865670_866606_+|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>NZ_CP042153.1|WP_000369730.1|867374_868286_+|RNase-adapter-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLENMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>NZ_CP042153.1|WP_001248939.1|868282_869278_+|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>NZ_CP042153.1|WP_000006551.1|869388_870333_+|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>NZ_CP042153.1|WP_001049165.1|870896_871484_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>NZ_CP042153.1|WP_114306606.1|871726_872629_-|TIGR01777-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKVLFNASATGYYPPDLFMGYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGMILSNEGGALQTMKLPYKYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE

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Crispr_ID: NZ_CP042153_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042153_5

867008-867098

Unclear

Consensus_repeat	Method
TCTGTGTTGGGGCCCACACCCCAACTCGCATTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042153_5

>merge|NZ_CP042153|5|867008-867098|CRISPRCasFinder
TCTGTGTTGGGGCCCACACCCCAACTCGCATTGCCTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCACACCCCAACTTGCATTG

>NZ_CP042153|5|5|867008-867098|CRISPRCasFinder
TCTGTGTTGGGGCCCACACCCCAACTCGCATTG	CCTGTAGAATTTCTTTTCGAAATTC
TCTGTGTTGGGGCCCACACCCCAACTTGCATTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042153.1\|WP_114306606.1\|871726_872629_-\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|224015
NZ_CP042153.1\|WP_000006551.1\|869388_870333_+\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NZ_CP042153.1\|WP_000279415.1\|875839_876850_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|273675
NZ_CP042153.1\|WP_000134963.1\|865670_866606_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NZ_CP042153.1\|WP_000958224.1\|861886_862819_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
NZ_CP042153.1\|WP_001049165.1\|870896_871484_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
NZ_CP042153.1\|WP_000369730.1\|867374_868286_+\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|224574
NZ_CP042153.1\|WP_000057543.1\|864164_865604_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
NZ_CP042153.1\|WP_001260089.1\|878300_879062_+\|triose-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
NZ_CP042153.1\|WP_001248939.1\|868282_869278_+\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NZ_CP042153.1\|WP_000513305.1\|862824_863664_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
NZ_CP042153.1\|WP_145411579.1\|863671_864157_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_CP042153.1\|WP_001074756.1\|876988_878179_+\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
NZ_CP042153.1\|WP_000070831.1\|873331_873961_+\|DUF4887-domain-containing-protein	unknown	unknown	gnl\|CDD\|234750
NZ_CP042153.1\|WP_000654030.1\|874773_875787_+\|sugar-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225263
NZ_CP042153.1\|WP_000638419.1\|855878_856115_+\|CsbA-family-protein	unknown	unknown	gnl\|CDD\|227234
NZ_CP042153.1\|WP_000229241.1\|856383_858369_+\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
NZ_CP042153.1\|WP_000538141.1\|855231_855882_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|378993
NZ_CP042153.1\|WP_114306605.1\|858376_861223_+\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_CP042153.1\|WP_000753318.1\|854218_855058_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451

Protein	Function_ID	Function_description	E-value
NZ_CP042153.1\|WP_114306606.1\|871726_872629_-\|TIGR01777-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	3.56838e-154
NZ_CP042153.1\|WP_000006551.1\|869388_870333_+\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
NZ_CP042153.1\|WP_000279415.1\|875839_876850_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	0
NZ_CP042153.1\|WP_000134963.1\|865670_866606_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
NZ_CP042153.1\|WP_000958224.1\|861886_862819_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
NZ_CP042153.1\|WP_001049165.1\|870896_871484_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
NZ_CP042153.1\|WP_000369730.1\|867374_868286_+\|RNase-adapter-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	5.38488e-169
NZ_CP042153.1\|WP_000057543.1\|864164_865604_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.14043e-06
NZ_CP042153.1\|WP_001260089.1\|878300_879062_+\|triose-phosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	2.84083e-146
NZ_CP042153.1\|WP_001248939.1\|868282_869278_+\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
NZ_CP042153.1\|WP_000513305.1\|862824_863664_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.75588e-120
NZ_CP042153.1\|WP_145411579.1\|863671_864157_+\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.25079e-30
NZ_CP042153.1\|WP_001074756.1\|876988_878179_+\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NZ_CP042153.1\|WP_000070831.1\|873331_873961_+\|DUF4887-domain-containing-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	5.80381e-05
NZ_CP042153.1\|WP_000654030.1\|874773_875787_+\|sugar-binding-transcriptional-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	1.39665e-92
NZ_CP042153.1\|WP_000638419.1\|855878_856115_+\|CsbA-family-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
NZ_CP042153.1\|WP_000229241.1\|856383_858369_+\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP042153.1\|WP_000538141.1\|855231_855882_+\|HD-domain-containing-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
NZ_CP042153.1\|WP_114306605.1\|858376_861223_+\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_CP042153.1\|WP_000753318.1\|854218_855058_+\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	7.40441e-41

>NZ_CP042153.1|WP_000134963.1|865670_866606_+|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>NZ_CP042153.1|WP_000057543.1|864164_865604_+|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>NZ_CP042153.1|WP_145411579.1|863671_864157_+|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVEFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>NZ_CP042153.1|WP_000513305.1|862824_863664_+|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>NZ_CP042153.1|WP_000958224.1|861886_862819_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>NZ_CP042153.1|WP_114306605.1|858376_861223_+|excinuclease-ABC-subunit-UvrA
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRCYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIDVPEYRRPASDRKISIRGARSNNLKGIDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>NZ_CP042153.1|WP_000229241.1|856383_858369_+|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIKEIVDGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>NZ_CP042153.1|WP_000638419.1|855878_856115_+|CsbA-family-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>NZ_CP042153.1|WP_000538141.1|855231_855882_+|HD-domain-containing-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>NZ_CP042153.1|WP_000753318.1|854218_855058_+|CHAP-domain-containing-protein
MKKTLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKSPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTLEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>NZ_CP042153.1|WP_000369730.1|867374_868286_+|RNase-adapter-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLENMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>NZ_CP042153.1|WP_001248939.1|868282_869278_+|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>NZ_CP042153.1|WP_000006551.1|869388_870333_+|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>NZ_CP042153.1|WP_001049165.1|870896_871484_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>NZ_CP042153.1|WP_114306606.1|871726_872629_-|TIGR01777-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKVLFNASATGYYPPDLFMGYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGMILSNEGGALQTMKLPYKYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE
>NZ_CP042153.1|WP_000070831.1|873331_873961_+|DUF4887-domain-containing-protein
MSNQNYDYNKNEDGSKKKMSTTAKVVSIATVLLLLGGLVFAIFAYVDHSNKAKERMLNEQKQEQKEKRQKENAEKERKKKQQEEKEQNELDSQANQYQQLPQQNQYQYVPPQQQAPTKQRPAKEENDDKASKDESKDKDDNASQDKSDDNQKKTDDNKQPAQPKPQPQQPTPKPNNNQQNNQSNQQAKPQAPQQNSQSTTNKQNNANDK
>NZ_CP042153.1|WP_000654030.1|874773_875787_+|sugar-binding-transcriptional-regulator
MKDLLQAQQKLIPDLIDKMYKRFSILTTISKNQPVGRRSLSEHMDMTERVLRSETDMLKKQDLIKVKPTGMEITAEGEQLISQLKGYFDIYADDNRLSEGIKNKFQIKEVHVVPGDADNSQSVKTELGRQAGQLLEGILQEDAIVAVTGGSTMACVSEAIHLLPYNVFFVPARGGLGENVVFQANTIAASMAQQAGGYYTTMYVPDNVSETTYNTLLLEPSVINTLDKIKQANVILHGIGDALKMAHRRQSPEKVIEQLQHHQAVGEAFGYYFDTQGQIVHKVKTIGLQLEDLESKDFIFAVAGGKSKGEAIKAYLTIAPKNTVLITDEAAAKIILE
>NZ_CP042153.1|WP_000279415.1|875839_876850_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLPELSK
>NZ_CP042153.1|WP_001074756.1|876988_878179_+|phosphoglycerate-kinase
MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVVEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
>NZ_CP042153.1|WP_001260089.1|878300_879062_+|triose-phosphate-isomerase
MRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTAVKEGKAQGLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIFKHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSEDQLKSVVIAYEPIWAIGTGKSSTSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLKVEDFVQLLEGAK

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Crispr_ID: NZ_CP042153_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042153_6

910423-910504

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042153_6

>merge|NZ_CP042153|6|910423-910504|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGAGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>NZ_CP042153|6|6|910423-910504|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGAGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042153.1\|WP_000662306.1\|909325_909439_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000270270.1\|914736_915957_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP042153.1\|WP_000589549.1\|908367_908724_+\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
NZ_CP042153.1\|WP_000560872.1\|918129_918351_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224393
NZ_CP042153.1\|WP_000732325.1\|913771_914593_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_CP042153.1\|WP_000124597.1\|918351_918624_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379251
NZ_CP042153.1\|WP_000422908.1\|907213_907753_+\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
NZ_CP042153.1\|WP_000974460.1\|905844_906267_-\|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
NZ_CP042153.1\|WP_078068262.1\|905642_905828_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_001065801.1\|911494_911791_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP042153.1\|WP_001147952.1\|907903_908224_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP042153.1\|WP_000571213.1\|912040_913066_+\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NZ_CP042153.1\|WP_000290491.1\|908881_909262_+\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_CP042153.1\|WP_000932223.1\|909440_910319_+\|DUF1963-domain-containing-protein	unknown	unknown	gnl\|CDD\|226395
NZ_CP042153.1\|WP_000569884.1\|904951_905446_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
NZ_CP042153.1\|WP_001661453.1\|915970_917359_-\|SAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|366887
NZ_CP042153.1\|WP_001661454.1\|917385_917958_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP042153.1\|WP_114306609.1\|913058_913754_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NZ_CP042153.1\|WP_001018962.1\|911115_911502_+\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
NZ_CP042153.1\|WP_000150011.1\|906414_907131_+\|type-I-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156

Protein	Function_ID	Function_description	E-value
NZ_CP042153.1\|WP_001661453.1\|915970_917359_-\|SAP-domain-containing-protein	gnl\|CDD\|366887	pfam02037, SAP, SAP domain. The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.	1.45613e-08
NZ_CP042153.1\|WP_000589549.1\|908367_908724_+\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
NZ_CP042153.1\|WP_000270270.1\|914736_915957_-\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.22693e-35
NZ_CP042153.1\|WP_000571213.1\|912040_913066_+\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	2.03316e-170
NZ_CP042153.1\|WP_000560872.1\|918129_918351_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224393	COG1476, COG1476, Predicted transcriptional regulators [Transcription].	2.70121e-07
NZ_CP042153.1\|WP_000732325.1\|913771_914593_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	9.92591e-112
NZ_CP042153.1\|WP_000124597.1\|918351_918624_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379251	pfam13545, HTH_Crp_2, Crp-like helix-turn-helix domain. This family represents a crp-like helix-turn-helix domain that is likely to bind DNA.	0.00479643
NZ_CP042153.1\|WP_000422908.1\|907213_907753_+\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	2.10032e-49
NZ_CP042153.1\|WP_000974460.1\|905844_906267_-\|organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	5.58225e-61
NZ_CP042153.1\|WP_001147952.1\|907903_908224_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.4922e-24
NZ_CP042153.1\|WP_000290491.1\|908881_909262_+\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	9.01516e-70
NZ_CP042153.1\|WP_000932223.1\|909440_910319_+\|DUF1963-domain-containing-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	7.89774e-77
NZ_CP042153.1\|WP_000569884.1\|904951_905446_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
NZ_CP042153.1\|WP_000150011.1\|906414_907131_+\|type-I-3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	3.2619e-146
NZ_CP042153.1\|WP_001661454.1\|917385_917958_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.25772e-06
NZ_CP042153.1\|WP_114306609.1\|913058_913754_+\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	6.92309e-99
NZ_CP042153.1\|WP_001018962.1\|911115_911502_+\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
NZ_CP042153.1\|WP_001065801.1\|911494_911791_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14

>NZ_CP042153.1|WP_000932223.1|909440_910319_+|DUF1963-domain-containing-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMQEETLSQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLNDLPEQQELFPVNEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQVHLKSLDADNEDIPFSGAFSIEFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDDNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>NZ_CP042153.1|WP_000662306.1|909325_909439_+|hypothetical-protein
MKENLLGTIIWSIATFYYSRMMKIMNLAILKIKIGGS
>NZ_CP042153.1|WP_000290491.1|908881_909262_+|glycine-cleavage-system-protein-GcvH
MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQLEALLTAEKYSEMIGE
>NZ_CP042153.1|WP_000589549.1|908367_908724_+|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>NZ_CP042153.1|WP_001147952.1|907903_908224_-|thioredoxin-family-protein
MQAIKSNESFKSIINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>NZ_CP042153.1|WP_000422908.1|907213_907753_+|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEEDMPKAPRKNRNLITLY
>NZ_CP042153.1|WP_000150011.1|906414_907131_+|type-I-3-dehydroquinate-dehydratase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFINDLYLNLISDLANINGIDMIDIEWQADIDIEKHQRIIKHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGEPQAPGQIDVTDLKAQVTLY
>NZ_CP042153.1|WP_000974460.1|905844_906267_-|organic-hydroperoxide-resistance-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>NZ_CP042153.1|WP_078068262.1|905642_905828_+|hypothetical-protein
METLCEEVKPVLEPVTFMMTKGQSFSVKYCQKFQSRIEKITNQKFLVGKFEFYVNFINNVE
>NZ_CP042153.1|WP_000569884.1|904951_905446_-|GNAT-family-N-acetyltransferase
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>NZ_CP042153.1|WP_001018962.1|911115_911502_+|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>NZ_CP042153.1|WP_001065801.1|911494_911791_+|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>NZ_CP042153.1|WP_000571213.1|912040_913066_+|methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEHGPVTQVFENPQHTVTKRFVKEDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>NZ_CP042153.1|WP_114306609.1|913058_913754_+|ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEFWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWIVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>NZ_CP042153.1|WP_000732325.1|913771_914593_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYDLDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFSPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>NZ_CP042153.1|WP_000270270.1|914736_915957_-|site-specific-integrase
MWYEKFTNKHGETKYRYYEKYKDPLTNKWRRVSVVLNKNGKQSQKEAQRLLNERIEAKLNDNTPTTLKSLTFHVACDEWFQNYIKTSGSKRTTIKTKLSKLNTLKKFVDEDILINKITLSYAQQVFDELDSKGYVYQVNKDALSIFKNVFEYTRRIYKLQDLEFLKDITLNKRIKSYDEVKAKRNKYLELNEIQSIIKDINMKAQKMHSGIHKRFYLFVALMTEFQALNGMRIGEMLAIKNEVIDFDNKSLNINGTIHWFHDESGGFGVKDTTKTESSYRTIGLSSRSCEILKKAILENKKDSKWNDGYLNRNFVFTNHKGNPMQTERFNKILRKSAKDVGIEKEISSHILRHSHISLLSQQGVSLKAIMDRVGHSDHRTTLSIYSHVTEQMDKDMMNKLEQVKLG
>NZ_CP042153.1|WP_001661453.1|915970_917359_-|SAP-domain-containing-protein
MKKIFYCFLLIFSILMLFGGINEVTQNKLTFIDIFMFAIFISLIVFSIVKLFKHNHLDYKSNKSNTNHKNISNSKTTQFNTVQSNDHIRKNNITHDIETNNTKKVKQVKSITNNKTNTLNKDQVKLNENVQENNQDLVIDVKDDNNNNYHYDLNANDILILHLNKNREVGKEVKNHFYLLENQINVDEILNKLINLDYLDIKSNFDVSLFYLKVPELKEILREYKLKLSGNKPELIERIKTNIDENAIKLPQVYVPTSKGNKIIGETEYILHFYNSPIISLGSAHKMAKEVLNIDDKIEYIYFYLLQQNQKSNNSDHRTANIINSLVLYYKKTNKDKDVIRKYTNYATYLSVTQGIHSAAFLYSSEENIIDRLFIYFNYHLEYYENMLFIDNVSRRLFKNLFYEDIKSFEDTDKNFCDEICELLFAQIYNNRNITLNNLPTINYVLEKIKKENEIRMTKYDF
>NZ_CP042153.1|WP_001661454.1|917385_917958_-|helix-turn-helix-transcriptional-regulator
MQQNSLEDFSNILKNFRKAEDLTLDTLSKYLGVSDVYVSKLENGKRFPSKNILFWYVLFMDQSQMHDDIEKLLTIFSENKKISYEQLRTEYDEFVKKFREKQKKHSSKIQRKEIKLTMNEFNQYQIEEIDEPYFDLKWLLNQSEYKLFYSGIDNKNSLGFNEVLSESDKKMLSEIVNSVIQRIYNDENQK
>NZ_CP042153.1|WP_000560872.1|918129_918351_+|helix-turn-helix-transcriptional-regulator
MIAKVNYLKRLIAFEGLSLKDFASEIEVNSNFLNSIVNGKRTTSPKTANKIAKRLNVDIKDIFIFIEEKEEVK
>NZ_CP042153.1|WP_000124597.1|918351_918624_+|helix-turn-helix-domain-containing-protein
MARTKLKDIPTKENTISEPKQVVVKPLFAKPNALASIFGISYSSTNRILKEWEKDPKGVDDLYYSLSSTMTVISIPRFEEYMKKRHKKWM

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Crispr_ID: NZ_CP042153_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042153_7

1192689-1192846

Orphan

Consensus_repeat	Method
TGCAAGTTGGCGGGGCCCCAACATAGAAGCTGGCGAAAAGTCAGC	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP042153_7

>merge|NZ_CP042153|7|1192689-1192846|PILER-CR
TGCAAGTTGGGGTGGGGCCCAACACAGAAGCTGGCGAAAAGTCAGCATACAAAAATGTGCAAGTTGGCGGGGCCCCAACATAGAAGCTGGCGAAAAGTCAGCATACAAAAATGTGCAAGTTGGCGGGGCCCCAACATAGAAGCTGGCGCAAAGTCAGC

>NZ_CP042153|7|1|1192689-1192846|PILER-CR
TGCAAGTTGGGGTGGGGCCCAACACAGAAGCTGGCGAAAAGTCAGC	ATACAAAAATG
TGCAAGTTGGCGGGGCCCCAACATAGAAGCTGGCGAAAAGTCAGCA	TACAAAAATGT
GCAAGTTGGCGGGGCCCCAACATAGAAGCTGGCGCAAAGTCAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042153.1\|WP_001802045.1\|1197805_1198030_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000659319.1\|1186881_1187469_+\|XTP/dITP-diphosphatase	unknown	unknown	gnl\|CDD\|184835
NZ_CP042153.1\|WP_000739210.1\|1188453_1188783_+\|complement-convertase-inhibitor-Ecb	unknown	unknown	gnl\|CDD\|289007
NZ_CP042153.1\|WP_001063553.1\|1199343_1200069_-\|superantigen-like-protein-SSL13	unknown	unknown	gnl\|CDD\|106307
NZ_CP042153.1\|WP_000584398.1\|1190222_1190729_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000739564.1\|1189151_1189553_-\|formyl-peptide-receptor-like-1-inhibitory-protein	unknown	unknown	gnl\|CDD\|171849
NZ_CP042153.1\|WP_000669537.1\|1191635_1191986_+\|complement-inhibitor-SCIN-B	unknown	unknown	gnl\|CDD\|371594
NZ_CP042153.1\|WP_001557163.1\|1194592_1195912_+\|ISL3-like-element-IS1181-family-transposase	unknown	unknown	gnl\|CDD\|225995
NZ_CP042153.1\|WP_000765708.1\|1197702_1197849_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_001032817.1\|1193033_1193219_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000041897.1\|1198519_1199236_-\|superantigen-like-protein-SSL12	unknown	unknown	gnl\|CDD\|171995
NZ_CP042153.1\|WP_001789955.1\|1193428_1193677_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000739531.1\|1200163_1200889_-\|superantigen-like-protein-SSL14	unknown	unknown	gnl\|CDD\|171855
NZ_CP042153.1\|WP_000231632.1\|1193840_1194074_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000049485.1\|1187461_1187965_+\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|223695
NZ_CP042153.1\|WP_145411582.1\|1192412_1192610_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000791581.1\|1190988_1191486_+\|complement-convertase-inhibitor-Efb	unknown	unknown	gnl\|CDD\|289007
NZ_CP042153.1\|WP_001791787.1\|1188092_1188260_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_001039659.1\|1186069_1186870_+\|glutamate-racemase	unknown	unknown	gnl\|CDD\|234851
NZ_CP042153.1\|WP_000857488.1\|1196070_1197030_-\|beta-channel-forming-cytolysin	unknown	unknown	gnl\|CDD\|273388

Protein	Function_ID	Function_description	E-value
NZ_CP042153.1\|WP_000659319.1\|1186881_1187469_+\|XTP/dITP-diphosphatase	gnl\|CDD\|184835	PRK14822, PRK14822, XTP/dITP diphosphatase.	6.07313e-114
NZ_CP042153.1\|WP_000739210.1\|1188453_1188783_+\|complement-convertase-inhibitor-Ecb	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	2.22818e-21
NZ_CP042153.1\|WP_001063553.1\|1199343_1200069_-\|superantigen-like-protein-SSL13	gnl\|CDD\|106307	PRK13349, PRK13349, superantigen-like protein; Reviewed.	3.51282e-147
NZ_CP042153.1\|WP_000739564.1\|1189151_1189553_-\|formyl-peptide-receptor-like-1-inhibitory-protein	gnl\|CDD\|171849	PRK13033, PRK13033, formyl peptide receptor-like 1 inhibitory protein; Reviewed.	4.48566e-77
NZ_CP042153.1\|WP_000049485.1\|1187461_1187965_+\|metallophosphoesterase	gnl\|CDD\|223695	COG0622, COG0622, Predicted phosphoesterase [General function prediction only].	4.70588e-44
NZ_CP042153.1\|WP_001557163.1\|1194592_1195912_+\|ISL3-like-element-IS1181-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.75686e-114
NZ_CP042153.1\|WP_001039659.1\|1186069_1186870_+\|glutamate-racemase	gnl\|CDD\|234851	PRK00865, PRK00865, glutamate racemase; Provisional.	2.38427e-134
NZ_CP042153.1\|WP_000669537.1\|1191635_1191986_+\|complement-inhibitor-SCIN-B	gnl\|CDD\|371594	pfam11546, CompInhib_SCIN, Staphylococcal complement inhibitor SCIN. SCIN is released by Staphylococcus aureus to counteract the host immune defense. The protein binds to and inhibits C3 convertases on the bacterial surface, reducing phagocytosis and blocking downstream effector functions by C3b deposition on its surface. An 18 residue stretch 31-48 is crucial for SCIN activity.	2.0882e-48
NZ_CP042153.1\|WP_000041897.1\|1198519_1199236_-\|superantigen-like-protein-SSL12	gnl\|CDD\|171995	PRK13350, PRK13350, superantigen-like protein; Reviewed.	2.65762e-152
NZ_CP042153.1\|WP_000739531.1\|1200163_1200889_-\|superantigen-like-protein-SSL14	gnl\|CDD\|171855	PRK13043, PRK13043, superantigen-like protein; Reviewed.	1.6289e-161
NZ_CP042153.1\|WP_000791581.1\|1190988_1191486_+\|complement-convertase-inhibitor-Efb	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	2.84801e-27
NZ_CP042153.1\|WP_000857488.1\|1196070_1197030_-\|beta-channel-forming-cytolysin	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	1.66722e-141

>NZ_CP042153.1|WP_145411582.1|1192412_1192610_+|hypothetical-protein
MAGPQHREIGSPISTDNASWGGAQHRSWRKVSIQKCASWRGPNTENFEKKFYKQCKLGWGHNREK
>NZ_CP042153.1|WP_000669537.1|1191635_1191986_+|complement-inhibitor-SCIN-B
MKFKKYILTGTLALLLSSTGIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSNVYALAAGSLNPYYKRTIMMNEYRAKAALKKNDFVSMADAKVALEKIYKEIDEIINR
>NZ_CP042153.1|WP_000791581.1|1190988_1191486_+|complement-convertase-inhibitor-Efb
MKNKLIAKSLLTIAAIGITTTTIASTADASEGYGPREKKPVSINHNIVEYNDGTFKYQSRPKFNSTPKYIKFKHDYNILEFNDGTFEYGARPQFNKPAAKTDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVR
>NZ_CP042153.1|WP_000584398.1|1190222_1190729_+|hypothetical-protein
MIIKILTILLLLCILSYLVTNRKKPFLFLKTLFMGVVFIFIGYISLAISAVIIYGIIQFITIDFGSFFLMGIILILISSIFQLFIVRLLFRKKNVDLTEVVVLEHLIQWFLVYFAIYQAVNEKMDINDINIDNFQSVFFDVSNLNLVILPTLIISWVTIFNYRMRSYK
>NZ_CP042153.1|WP_000739564.1|1189151_1189553_-|formyl-peptide-receptor-like-1-inhibitory-protein
MKKNITKTIIASTVIAAGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIVKKLSQGDVKKAVVRIKDGGPRDYYTFDLTRPLEENRKNIKVVKNGEIDSIYWD
>NZ_CP042153.1|WP_000739210.1|1188453_1188783_+|complement-convertase-inhibitor-Ecb
MKKNFIGKSILSIAAISLTVSTFAGESHAQTKNVEAAKKYDQYQTNFKKQVNKKVVDAQKAVNLFKRTRTVATHRKAQRAVNLIHFQHSYEKKKLQRQIDLVLKYNTLK
>NZ_CP042153.1|WP_001791787.1|1188092_1188260_+|hypothetical-protein
MKRIVILENVIVDNPIWLNHVDYLVKSVLLKSIKLRFQEVRKFEILVKIMNRIHI
>NZ_CP042153.1|WP_000049485.1|1187461_1187965_+|metallophosphoesterase
MSKWIIVSDNHTESGVLYQIYEMHPDADVYLHLGDSEFAYDDTELSLFNRVKGNCDFYPEFENEAVAKYNDVKAFYTHGHLYQVNRTRDLLAEKGLELGCLFVFYGHTHVAKYEYINGVHVINPGSISQSRSSMEETYAEVIIDDQTLHGTINFKNRHHETISHTTF
>NZ_CP042153.1|WP_000659319.1|1186881_1187469_+|XTP/dITP-diphosphatase
MKEIVIASNNQGKINDFKVIFPDYHVIGISELIPDFDVEETGSTFEENAILKSEAAAKALNKTVIADDSGLEVFALNGEPGIYSARYAGENKSDEANIEKLLNKLGNTTDRRAQFVCVISMSGPDMETKVFKGTVSGEIADGKYGENGFGYDPIFYVPKLDKTMAQLSKEQKGQISHRRNAINLLQAFLEGEKNV
>NZ_CP042153.1|WP_001039659.1|1186069_1186870_+|glutamate-racemase
MNKPIGVIDSGVGGLTVAKEIMRQLPNETIYYLGDIGRCPYGPRPGEQVKQYTVEIARKLMEFDIKMLVIACNTATAVALEYLQKTLSIPVIGVIEPGARTAIMTTRNQNVLVLGTEGTIKSEAYRTHIKRINPHVEVHGVACPGFVPLVEQMRYSDPTITSIVIHQTLKRWRNSESDTVILGCTHYPLLYKPIYDYFGGKKTVISSGLETAREVSALLTFSNEHASYTEHPDHRFFATGDPTHITNIIKEWLNLSVNVERISVND
>NZ_CP042153.1|WP_001032817.1|1193033_1193219_-|hypothetical-protein
MNKHINKKATKLLEDYKKVQQRKSEETDRGCLKSVIMLIVLFFLIIFGIVACSTNVNFFFQ
>NZ_CP042153.1|WP_001789955.1|1193428_1193677_-|hypothetical-protein
MYNIIVYIACMINFGLIIVPLLTTNDADFVWTSSSLIYMILLTSIILIVYIKTKDSLQLTIFILNIALIILYCAPLLFIYVF
>NZ_CP042153.1|WP_000231632.1|1193840_1194074_-|hypothetical-protein
MVFNDWEINVVYSGEHEVVTNEKSLFVIDEFYDVAIAIYYLDGKLKVAHVNYGSDFTIDVANKVFELNIQNPNVDEH
>NZ_CP042153.1|WP_001557163.1|1194592_1195912_+|ISL3-like-element-IS1181-family-transposase
MCNDTLELLRIKDENIKYINQEIDVIIKGKKATVVNAVLTYKPSACYCCGVKNEGQIHKHGKRVSRITLLKTQGYNTYLNLAKQRFKCLECNGTFTAKTSIVDESCFISRCVTQKVIEEATKVKTEIDTAEDNCISPSTVSRIRTKAANSLRIKPFNCLPEHIAMDEFKSVKNVTGSMSFIFIDNDTHDVIDILENRTTRFLRAYFERFDLKNRQQVKTVTIDMYEPYVRLFRDLFPNAAIIFDRFHIVQHLNRELNKYRVQVMNEYRNKKGPNYTIFKNNWKVLLMDTSKTIFSKYRWNKSFKAYKRSSDIVEFMLSKDDILRRSYELVQGLRKDLRLCNWPKFINRLNSVSKKSVSKGVWKVVKYYRKHQRMLRNTIYYPAFNNGAIEGINNKIKLIKRISFGYRNFNNFKARIMMIFSLYKGEKKKTTKPNNGLAA
>NZ_CP042153.1|WP_000857488.1|1196070_1197030_-|beta-channel-forming-cytolysin
MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAAENFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
>NZ_CP042153.1|WP_000765708.1|1197702_1197849_+|hypothetical-protein
MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE
>NZ_CP042153.1|WP_001802045.1|1197805_1198030_+|hypothetical-protein
MLIQERGLKMTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYVSLKEH
>NZ_CP042153.1|WP_000041897.1|1198519_1199236_-|superantigen-like-protein-SSL12
MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHFSFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQLWWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAREALIKNKILYTENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD
>NZ_CP042153.1|WP_001063553.1|1199343_1200069_-|superantigen-like-protein-SSL13
MNNNITKKIILSTTLLLLGTAFTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYLTFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDSFALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIRQTLIKSKKLYNNSYNKGQIKITGTDNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKSN
>NZ_CP042153.1|WP_000739531.1|1200163_1200889_-|superantigen-like-protein-SSL14
MKKNIMNKLVLSTALLLLGTTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHFSLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEGYWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIRQTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPKNAQIEVILEKSN

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Crispr_ID: NZ_CP042153_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042153_8

1675574-1675658

Orphan

Consensus_repeat	Method
CACCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042153_8

>merge|NZ_CP042153|8|1675574-1675658|CRISPRCasFinder
CACCCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCTCTGTGTTGGGGCCCACACCCCAACTTGCATTGCCTGTAGAA

>NZ_CP042153|8|7|1675574-1675658|CRISPRCasFinder
CACCCCAACTTGCATTGTCTGTAGAA	ATTGGGAATCCAATTTCTCTGTGTTGGGGCCCA
CACCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042153.1\|WP_001104607.1\|1668286_1669225_-\|50S-ribosomal-protein-L11-methyltransferase	unknown	unknown	gnl\|CDD\|283886
NZ_CP042153.1\|WP_000218103.1\|1674140_1675265_-\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NZ_CP042153.1\|WP_000439693.1\|1681532_1681994_-\|ComE-operon-protein-2	unknown	unknown	gnl\|CDD\|131622
NZ_CP042153.1\|WP_001282563.1\|1678295_1679270_-\|DNA-polymerase-III-subunit-delta	unknown	unknown	gnl\|CDD\|235511
NZ_CP042153.1\|WP_001019324.1\|1683884_1684469_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224627
NZ_CP042153.1\|WP_000627144.1\|1673062_1674040_-\|heat-inducible-transcription-repressor-HrcA	unknown	unknown	gnl\|CDD\|273017
NZ_CP042153.1\|WP_000368338.1\|1675830_1677654_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_CP042153.1\|WP_001802667.1\|1664783_1665467_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223961
NZ_CP042153.1\|WP_001802022.1\|1682085_1682772_-\|ComEA-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|224472
NZ_CP042153.1\|WP_000182211.1\|1672404_1673031_-\|nucleotide-exchange-factor-GrpE	unknown	unknown	gnl\|CDD\|237622
NZ_CP042153.1\|WP_000048060.1\|1665710_1665887_-\|30S-ribosomal-protein-S21	unknown	unknown	gnl\|CDD\|234707
NZ_CP042153.1\|WP_001088020.1\|1683530_1683884_-\|ribosome-silencing-factor	unknown	unknown	gnl\|CDD\|223870
NZ_CP042153.1\|WP_001119021.1\|1669228_1670368_-\|molecular-chaperone-DnaJ	unknown	unknown	gnl\|CDD\|237656
NZ_CP042153.1\|WP_000725167.1\|1684458_1685028_-\|nicotinate-(nicotinamide)-nucleotide-adenylyltransferase	unknown	unknown	gnl\|CDD\|273101
NZ_CP042153.1\|WP_001190120.1\|1667532_1668285_-\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	unknown	unknown	gnl\|CDD\|224303
NZ_CP042153.1\|WP_000108667.1\|1666179_1667526_-\|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB	unknown	unknown	gnl\|CDD\|223694
NZ_CP042153.1\|WP_000034716.1\|1670503_1672336_-\|molecular-chaperone-DnaK	unknown	unknown	gnl\|CDD\|234715
NZ_CP042153.1\|WP_114306645.1\|1682811_1683528_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP042153.1\|WP_000953309.1\|1679326_1681474_-\|DNA-internalization-related-competence-protein-ComEC/Rec2	unknown	unknown	gnl\|CDD\|225212
NZ_CP042153.1\|WP_001274017.1\|1677999_1678251_+\|30S-ribosomal-protein-S20	unknown	unknown	gnl\|CDD\|178943

Protein	Function_ID	Function_description	E-value
NZ_CP042153.1\|WP_001104607.1\|1668286_1669225_-\|50S-ribosomal-protein-L11-methyltransferase	gnl\|CDD\|283886	pfam06325, PrmA, Ribosomal protein L11 methyltransferase (PrmA). This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.	9.7051e-134
NZ_CP042153.1\|WP_000218103.1\|1674140_1675265_-\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NZ_CP042153.1\|WP_000439693.1\|1681532_1681994_-\|ComE-operon-protein-2	gnl\|CDD\|131622	TIGR02571, putative_dCMP_deaminase, ComE operon protein 2. This protein is found in the ComE operon for "late competence" as characterized in B. subtilis. Proteins in this family contain homology to a cytidine/deoxycytidine deaminase domain family (pfam00383), and may carry out this activity.	4.81051e-102
NZ_CP042153.1\|WP_001282563.1\|1678295_1679270_-\|DNA-polymerase-III-subunit-delta	gnl\|CDD\|235511	PRK05574, holA, DNA polymerase III subunit delta; Reviewed.	4.1415e-104
NZ_CP042153.1\|WP_001019324.1\|1683884_1684469_-\|HD-domain-containing-protein	gnl\|CDD\|224627	COG1713, COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism [Coenzyme metabolism].	2.21948e-80
NZ_CP042153.1\|WP_000627144.1\|1673062_1674040_-\|heat-inducible-transcription-repressor-HrcA	gnl\|CDD\|273017	TIGR00331, Heat-inducible_transcription_repressor_HrcA, heat shock gene repressor HrcA. HrcA represses the class I heat shock operons groE and dnaK; overproduction prevents induction of these operons by heat shock while deletion allows constitutive expression even at low temperatures. In Bacillus subtilis, hrcA is the first gene of the dnaK operon and so is itself a heat shock gene. [Regulatory functions, DNA interactions].	2.05887e-119
NZ_CP042153.1\|WP_000368338.1\|1675830_1677654_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_CP042153.1\|WP_001802667.1\|1664783_1665467_-\|hypothetical-protein	gnl\|CDD\|223961	COG1030, NfeD, Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones].	8.78003e-63
NZ_CP042153.1\|WP_001802022.1\|1682085_1682772_-\|ComEA-family-DNA-binding-protein	gnl\|CDD\|224472	COG1555, ComEA, DNA uptake protein and related DNA-binding proteins [DNA replication, recombination, and repair].	1.06297e-33
NZ_CP042153.1\|WP_000182211.1\|1672404_1673031_-\|nucleotide-exchange-factor-GrpE	gnl\|CDD\|237622	PRK14140, PRK14140, heat shock protein GrpE; Provisional.	3.74407e-81
NZ_CP042153.1\|WP_000048060.1\|1665710_1665887_-\|30S-ribosomal-protein-S21	gnl\|CDD\|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	1.15423e-10
NZ_CP042153.1\|WP_001088020.1\|1683530_1683884_-\|ribosome-silencing-factor	gnl\|CDD\|223870	COG0799, COG0799, Uncharacterized homolog of plant Iojap protein [Function unknown].	5.95861e-47
NZ_CP042153.1\|WP_001119021.1\|1669228_1670368_-\|molecular-chaperone-DnaJ	gnl\|CDD\|237656	PRK14280, PRK14280, molecular chaperone DnaJ.	0
NZ_CP042153.1\|WP_000725167.1\|1684458_1685028_-\|nicotinate-(nicotinamide)-nucleotide-adenylyltransferase	gnl\|CDD\|273101	TIGR00482, Probable_nicotinate-nucleotide_adenylyltransferase, nicotinate (nicotinamide) nucleotide adenylyltransferase. This model represents the predominant bacterial/eukaryotic adenylyltransferase for nicotinamide-nucleotide, its deamido form nicotinate nucleotide, or both. The first activity, nicotinamide-nucleotide adenylyltransferase (EC 2.7.7.1), synthesizes NAD by the salvage pathway, while the second, nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18) synthesizes the immediate precursor of NAD by the de novo pathway. In E. coli, NadD activity is biased toward the de novo pathway while salvage activity is channeled through the multifunctional NadR protein, but this division of labor may be exceptional. The given name of this model, nicotinate (nicotinamide) nucleotide adenylyltransferase, reflects the lack of absolute specificity with respect to substrate amidation state in most species. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides].	2.64141e-76
NZ_CP042153.1\|WP_001190120.1\|1667532_1668285_-\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	gnl\|CDD\|224303	COG1385, COG1385, Uncharacterized protein conserved in bacteria [Function unknown].	1.90273e-91
NZ_CP042153.1\|WP_000108667.1\|1666179_1667526_-\|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB	gnl\|CDD\|223694	COG0621, MiaB, 2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis].	0
NZ_CP042153.1\|WP_000034716.1\|1670503_1672336_-\|molecular-chaperone-DnaK	gnl\|CDD\|234715	PRK00290, dnaK, molecular chaperone DnaK; Provisional.	0
NZ_CP042153.1\|WP_114306645.1\|1682811_1683528_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	8.8257e-16
NZ_CP042153.1\|WP_000953309.1\|1679326_1681474_-\|DNA-internalization-related-competence-protein-ComEC/Rec2	gnl\|CDD\|225212	COG2333, ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only].	1.49563e-90
NZ_CP042153.1\|WP_001274017.1\|1677999_1678251_+\|30S-ribosomal-protein-S20	gnl\|CDD\|178943	PRK00239, rpsT, 30S ribosomal protein S20; Reviewed.	1.42889e-17

>NZ_CP042153.1|WP_000218103.1|1674140_1675265_-|oxygen-independent-coproporphyrinogen-III-oxidase
MTVQSAYIHIPFCVRICTYCDFNKYFIQNQPVDEYLDALITEMSTAKYRNLKTMYVGGGTPTALSINQLERLLKAIRDTFTITGEYTFEANPDELTKEKVQLLEKYGVNRISMGVQTFKPELLSVLGRTHNTEDIYTSVLNAKNAGIKSISLDLMYHLPKQTIEDFEQSLDLALDMDIQHISSYGLILEPKTQFYNMYRKGLLKLPNEDLGADMYQLLMSKIEQSPFHQYEISNFALDGHESEHNKVYWFNEEYYGFGAGASGYVDGVRYTNINPVNHYIKAINKESKAILVSNKPSLTERMEEEMFLGLRLNEGVSSSRFKKKFDQSIESVFGQTINNLKEKELIVEKNDAIALTKRGKVIGNEVFEAFLIND
>NZ_CP042153.1|WP_000627144.1|1673062_1674040_-|heat-inducible-transcription-repressor-HrcA
MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLEQTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVEHVHLASDIPFSNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLINTMNNHISNQSNSIYMGGKVKLIDALNESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQLLNRIW
>NZ_CP042153.1|WP_000182211.1|1672404_1673031_-|nucleotide-exchange-factor-GrpE
MTNKDESVEKNTESTVEETNIKQNIDDSVEQAEESKGHLQDEAIEETSDENVIEEIDPKDQKINELQQLADENEEKYLRLYAEFENYKRRIQKENEINKTYQAQRVLTDILPAIDNIERALQIEGDDETFKSLQKGVQMVHESLINALKDNGLEVIKTEGEAFDPNIHQAVVQDDNPDFESGEITQELQKGYKLKDRVLRPSMVKVNQ
>NZ_CP042153.1|WP_000034716.1|1670503_1672336_-|molecular-chaperone-DnaK
MSKIIGIDLGTTNSCVTVLEGDEPKVIQNPEGSRTTPSVVAFKNGETQVGEVAKRQAITNPNTVQSIKRHMGTDYKVDIEGKSYTPQEISAMILQNLKNTAESYLGEKVDKAVITVPAYFNDAERQATKDAGKIAGLEVERIINEPTAAALAYGLDKTDKDEKVLVFDLGGGTFDVSILELGDGVFEVLSTAGDNKLGGDDFDQVIIDYLVAEFKKENGVDLSQDKMALQRLKDAAEKAKKDLSGVSQTQISLPFISAGENGPLHLEVNLTRSKFEELSDSLIRRTMEPTRQAMKDAGLTNSDIDEVILVGGSTRIPAVQEAVKKEIGKEPNKGVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIEILGGRMNTLIERNTTIPTSKSQIYSTAVDNQPSVDVHVLQGERPMAADNKTLGRFQLTDIPPAERGKPQIEVTFDIDKNGIVNVTAKDLGTNKEQRITIQSSSSLSDEEIDRMVKDAEVNAEADKKRREEVDLRNEADSLVFQVEKTLTDLGENIGEEDKKSAEEKKDALKTALEGQDIEDIKSKKEELEKVIQELSAKVYEQAAQQQQQAQGANAGQNNDSTVEDAEFKEVKDDDKK
>NZ_CP042153.1|WP_001119021.1|1669228_1670368_-|molecular-chaperone-DnaJ
MAKRDYYEVLGISKDASKDEIKKAYRKLSKKYHPDINKEEGADEKFKEISEAYEVLSDDNKRASYDQFGHDGPQGFGGQGFNGSDFGGFSGFGGGGFEDIFSSFFGGGRQRDPNAPQKGDDLQYTMTLTFEEAVFGTTKEISIRKDVTCETCHGDGAKPGTSKKTCSYCNGAGHVAVEQNTILGRVRTEQVCPKCNGSGQEFEEACPTCHGKGTENKTVKLEVKVPEGVDNEQQIRLAGEGSPGVNGGPAGDLYVVFRVKPSETFKRDGDDIYYKLNVSFPQAALGDEIKIPTLNNEVMLTIPAGTQTGKQFRLKEKGIKNVHGYGYGDLYVDIKVVTPTKLTDRQKELMKEFAQLNGEEINEQPSNFKDRAKRFFKGE
>NZ_CP042153.1|WP_001104607.1|1668286_1669225_-|50S-ribosomal-protein-L11-methyltransferase
MNWTELSIIINHEAVELATNILENHGSNGVVIEDSDDLINQPEDKYGEIYALKKEDYPDKGVRLKAYFNEMTYDDKLRQQIKDELLNLDELDQHNIQFSEQIIAETDWENEWKNYFHPFRASKKFTIVPSWETYAKEADEELCIELDPGMAFGTGDHPTTSMCLKAIETYVLPQHSVIDVGTGSGILSIASHLIGVKRIKALDIDEMAVSVAKENFRRNHCETLIEAVPGNLLKDETEKFDIVIANILAHIIDEMIEDAYNTLNEGGYFITSGIIKEKYEGIQSHMERVGFKIISEQHDNGWVCLVGQKVSE
>NZ_CP042153.1|WP_001190120.1|1667532_1668285_-|16S-rRNA-(uracil(1498)-N(3))-methyltransferase
MQRYFIDQNADVSQRFFITKKEDIHHITNVMRYDVGSKIILTFNDQTVYLCEIADITSDKIAVDLKEKQNINTELPVDVTICSGLIKADKYEWLLQKATELGASSFIAVSMERSIVKLNEAKVVKKIERWQKIIKEAAEQSYRLVIPSIQFESNLKLICDTIDNYDYILIAYEEEAKDGELSNFKQTLQQFKAQDKVLMIFGPEGGLSENEISLFSNTSTVVGLGPRILRAETAPLYALSAISYEKELMG
>NZ_CP042153.1|WP_000108667.1|1666179_1667526_-|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB
MSTVAFHTLGCKVNHYETEAIWQLFKEANYERVDFEANADVFVINTCTVTNTGDKKSRQIIRRAIRQNPDAVICVTGCYAQTSSAEIMEIPGVDVVVGTQDRHKLLGYIDEFRKERQPINGVGNIMKNRKYEELDVPYFTDRTRASLKIQEGCNNFCTFCIIPWARGLMRSRDPEKVVEQATQLVNSGYKEIVLTGIHTGGYGQDLKDYNLAQLLRDLETINGLERIRISSIEASQLTDEVIDVLERSTKVVRHLHIPLQSGSDTVLKRMRRKYTMDRFSERLTKLHKALPDLAVTSDVIVGFPGETEAEFQETYDFIVKHKFSELHVFPYSPRIGTPAARMDDQIDEEIKNERVHKLITLSNQLGKLYASKFDQDVLEVIPEEQGDTEGTLVGYADNYMKVQFEGDESLIGQIVKVKITQANYPLNEGQAIKVVDFATNKSDREVLV
>NZ_CP042153.1|WP_000048060.1|1665710_1665887_-|30S-ribosomal-protein-S21
MSKTVVRKNESLEDALRRFKRSVSKSGTIQEVRKREFYEKPSVKRKKKSEAARKRKFK
>NZ_CP042153.1|WP_001802667.1|1664783_1665467_-|hypothetical-protein
MTTILESTAGDTWVEQVSNIIVQPIFTLILTCLTFLGFVYQLYSKKINAAGIIATLSLLILFLGFLIQGNVNMHSILIFSIGVILVVIELFVVGAVIGIIGMILITISITTLGDNLLFMLANVIVALILTIVEWVILVKIFNRKIPFLDKVILKDSTNSESGYNSHDNRSHLVGKTAQTVTDLRPAGIIFCENERIDAVSDGNFILRNKTVKILEVEGTRVVVREVD
>NZ_CP042153.1|WP_000368338.1|1675830_1677654_-|elongation-factor-4
MDNEQRLKRRENIRNFSIIAHIDHGKSTLADRILENTKSVETRDMQDQLLDSMDLERERGITIKLNAVRLKYEAKDGNTYTFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNELELLPVINKIDLPAAEPERVKQEIEDMIGLDQDDVVLASAKSNIGIEEILEKIVEVVPAPDGDPEAPLKALIFDSEYDPYRGVISSIRIVDGVVKAGDKIRMMATGKEFEVTEVGINTPKQLPVDELTVGDVGYIIASIKNVDDSRVGDTITLASRPASEPLQGYKKMNPMVYCGLFPIDNKNYNDLREALEKLQLNDASLEFEPESSQALGFGYRTGFLGMLHMEIIQERIEREFGIELIATAPSVIYQCILRDGSEVTVDNPAQMPDRDKIDKIFEPYVRATMMVPNDYVGAVMELCQRKRGQFINMDYLDDIRVNIVYELPLAEVVFDFFDQLKSNTKGYASFDYEFIENKESNLVKMDILLNGDKVDALSFIVHRDFAYERGKALVEKLKTLIPRQQFEVPVQAAIGQKIVARTNIKSMGKNVLAKCYGGDISRKRKLLEKQKAGKAKMKAVGNVEIPQDAFLAVLKMDDE
>NZ_CP042153.1|WP_001274017.1|1677999_1678251_+|30S-ribosomal-protein-S20
MANIKSAIKRVKTTEKAEARNISQKSAMRTAVKNAKTAVSNNADNKNELVSLAVKLVDKAAQSNLIHSNKADRIKSQLMTANK
>NZ_CP042153.1|WP_001282563.1|1678295_1679270_-|DNA-polymerase-III-subunit-delta
MSDNIVAIYGDVPELVEKQSAEIISQFLKSDRDDFNFVKYNLYETEIAPIVEETLTLPFFSDKKAILVKNAYIFTGEKAPKDMAHNVDQLIEFIEKYDGENLIVFEIYQNKLDERKKLTKTLKKHARLKKIEQMSEEEIKKWIQSKLNENFKDIKRDALDLFIELTGINFNIVSQEIEKLILFLGDRPTINKQDVNQIINRSLEQNVFLLTEYIQKRKKEQAIHLVKDLITMKEEPIKLLALITSNYRLFYQCKILSQKGYSGQQIAKTIGVHPYRVKLALGQVRHYQLDELLNIVDACAETDYKLKSSYMDKQLILELFILSL
>NZ_CP042153.1|WP_000953309.1|1679326_1681474_-|DNA-internalization-related-competence-protein-ComEC/Rec2
MLSTFLFILLLYITYRKNKIVYAPISLFLIIFSSWYLHYSQQAIFNYINYIERNSQFNERAQVIQIQRQGSDTYKGRLSLKNEIYPFFLTDKKNFDLKKIESRNCIVKGQFKVNENKFVTLKLQSIVVQSCLESNRSNLIEKHKQFIMNRIYDSGIKFPDRIMALITGDVKEINEQFKERVKEIGIYHLLAVSGSHIAAIVFLIYQPLKRLNLPLFVIKGITIIVLTLYAQYTNYAPSAVRAIIMTTLVLLITKQIKIKGIQLLAFAFIIMFILNPLVVYDIGFQFSFIISFFIMLLFPFLQQLSKLQSLFIITFIAQLASFIVAIPNFHQLQWVGFLSNLIFVPYYSIILFPLSILFFITSHFIVGLTPLNYLVDLSFNFHDWLLDLFTRIKQSHFSVPKFNDWIFIIFIISVYYIFWLLAKRKYILVTFWTIIILTLLITFPTNSHHKITMLNVGQGDSILYEGGKNQNVLIDTGGKVIDDTKQPSYSISKYHILPTLNERGINELEYLILTHPHNDHIGEVEYIISHIKIKHIVIYNKGYSSNTLMLLSKLSHKYNIKLMDVRQVSSFKLGDSSFLFFDSFIPNSRDKNEYSIITMITYQNKKVLLMGDASKNNESLLLKKYNLPEIDILKVGHHGSKTSSSKEFIEMIKPKISLISSGKNNMYHLPNIEVVKRLQRIRSRIYNSQQNGQVTIDLDDNLKVDSNSYGNASGL
>NZ_CP042153.1|WP_000439693.1|1681532_1681994_-|ComE-operon-protein-2
MERIKWEEYFMAQSHLLALRSTCQRLSVGATIVKDNRIIAGGYNGSVAGEVHCIDEGCLIEDGHCIRTIHAEMNALLQCAKQGVSTEGATIYVTHFPCLNCTKSIIQAGIKRIYYAEDYHNHEYATKLLKQSGIEFKKIPFSPEYVAKYLTKG
>NZ_CP042153.1|WP_001802022.1|1682085_1682772_-|ComEA-family-DNA-binding-protein
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSKNKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKNGNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI
>NZ_CP042153.1|WP_114306645.1|1682811_1683528_-|class-I-SAM-dependent-methyltransferase
MSQYAEMSLVYDQLTQDQPYEKWFEIVKNHCKDESNILDIGCGTGSLTVQLEALGNVTGMDLSVDMLTVAAQKSANVNWLEGDMTSFDLQQQFDIITIFCDSLNYLQDETAVIETFINVYHHLTDSGVFIFDVHTVYKMMTLFNNQSYIDDKGDIFLAWDAVQGDLPLSVYHDMTFFIRHEDETYSRFDESHFQRTFDEKTYLSWLAQVGFKHVETFTDFNIDKHNEDAERLFFIAKK
>NZ_CP042153.1|WP_001088020.1|1683530_1683884_-|ribosome-silencing-factor
MNSQELLAIAVDAIDNKKGEDTISLEMKGISDMTDYFVVTHGNNERQVQAIARAVKEVANEQNIEVKRMEGYNEARWILIDLADVVVHVFHKDERNYYNIEKLYQDAPLESYGQVAY
>NZ_CP042153.1|WP_001019324.1|1683884_1684469_-|HD-domain-containing-protein
MNIEKAKRLAKEKLPEKRYNHSLRVAETAIKLAEIYDGDTSKVELAGVLHDFCKYDDLGKMYQIVRQYELGNDLLSYGSEILHGPVCAAIMEHEYGINDEEVLMAIKYHTTGRQQMTKTEKLIFIADYIEPGRTIPGVDDIRDMAYNQGSLDKTIYEISKRTVLFLIQKDITVYNKTIDCLNYYNYSDERIKDD
>NZ_CP042153.1|WP_000725167.1|1684458_1685028_-|nicotinate-(nicotinamide)-nucleotide-adenylyltransferase
MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH

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Crispr_ID: NZ_CP042153_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042153_9

2251074-2251154

Orphan

Consensus_repeat	Method
CAACTTTAGTTGTTAGGGGCTCTT	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NZ_CP042153_9

>merge|NZ_CP042153|9|2251074-2251154|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTCAACTTTAGTTGTTAGGGGCTTCT

>NZ_CP042153|9|8|2251074-2251154|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTT	ATGCATGCGCTTAGCGCAGGCGCTCCTACTTTT
CAACTTTAGTTGTTAGGGGCTTCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042153.1\|WP_001792784.1\|2252273_2252432_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_001292149.1\|2261231_2261666_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_CP042153.1\|WP_000123398.1\|2243903_2245277_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
NZ_CP042153.1\|WP_000019734.1\|2248722_2249700_+\|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl\|CDD\|224151
NZ_CP042153.1\|WP_001792291.1\|2252026_2252209_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000908182.1\|2254014_2254797_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_CP042153.1\|WP_000334463.1\|2255028_2256834_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP042153.1\|WP_001127960.1\|2246209_2247148_-\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
NZ_CP042153.1\|WP_001802298.1\|2251489_2251594_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_001794441.1\|2252868_2252961_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000927371.1\|2259087_2261220_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP042153.1\|WP_001123303.1\|2243033_2243447_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NZ_CP042153.1\|WP_000495669.1\|2249965_2251057_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000808817.1\|2245948_2246179_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000070866.1\|2242390_2242834_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
NZ_CP042153.1\|WP_000160304.1\|2241559_2242270_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NZ_CP042153.1\|WP_000083807.1\|2257514_2259053_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP042153.1\|WP_001024092.1\|2247583_2248249_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
NZ_CP042153.1\|WP_000370925.1\|2253089_2253947_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_CP042153.1\|WP_000003759.1\|2248400_2248721_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042

Protein	Function_ID	Function_description	E-value
NZ_CP042153.1\|WP_000123398.1\|2243903_2245277_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	4.11455e-06
NZ_CP042153.1\|WP_000019734.1\|2248722_2249700_+\|CDF-family-zinc-efflux-transporter-CzrB	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.49165e-107
NZ_CP042153.1\|WP_001292149.1\|2261231_2261666_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_CP042153.1\|WP_001127960.1\|2246209_2247148_-\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
NZ_CP042153.1\|WP_000927371.1\|2259087_2261220_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.02509e-68
NZ_CP042153.1\|WP_001123303.1\|2243033_2243447_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.14887e-46
NZ_CP042153.1\|WP_000003759.1\|2248400_2248721_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
NZ_CP042153.1\|WP_000334463.1\|2255028_2256834_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP042153.1\|WP_000070866.1\|2242390_2242834_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
NZ_CP042153.1\|WP_000160304.1\|2241559_2242270_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
NZ_CP042153.1\|WP_000083807.1\|2257514_2259053_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_CP042153.1\|WP_001024092.1\|2247583_2248249_-\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.53858e-46
NZ_CP042153.1\|WP_000370925.1\|2253089_2253947_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	6.8047e-59
NZ_CP042153.1\|WP_000908182.1\|2254014_2254797_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	1.29094e-106

>NZ_CP042153.1|WP_000495669.1|2249965_2251057_+|hypothetical-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYAQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKDKKVVTEPKNTKVENGKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>NZ_CP042153.1|WP_000019734.1|2248722_2249700_+|CDF-family-zinc-efflux-transporter-CzrB
MSHSHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>NZ_CP042153.1|WP_000003759.1|2248400_2248721_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>NZ_CP042153.1|WP_001024092.1|2247583_2248249_-|SDR-family-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHCVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGEQDIKDALTQFEIEKD
>NZ_CP042153.1|WP_001127960.1|2246209_2247148_-|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>NZ_CP042153.1|WP_000808817.1|2245948_2246179_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>NZ_CP042153.1|WP_000123398.1|2243903_2245277_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVKKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>NZ_CP042153.1|WP_001123303.1|2243033_2243447_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>NZ_CP042153.1|WP_000070866.1|2242390_2242834_-|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>NZ_CP042153.1|WP_000160304.1|2241559_2242270_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>NZ_CP042153.1|WP_001802298.1|2251489_2251594_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NZ_CP042153.1|WP_001792291.1|2252026_2252209_-|hypothetical-protein
MIIFRFKVNAFFPVKLCLMIRFCLESCCIFRRHLLITFHNIRSKFIMFKYISSKCIICTG
>NZ_CP042153.1|WP_001792784.1|2252273_2252432_+|hypothetical-protein
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>NZ_CP042153.1|WP_001794441.1|2252868_2252961_+|hypothetical-protein
MTYGSIVAILCALFVIFFIPYMEKKDKKKK
>NZ_CP042153.1|WP_000370925.1|2253089_2253947_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>NZ_CP042153.1|WP_000908182.1|2254014_2254797_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKNISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATTGGVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEVRNEAHHLLKLVGISAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLNILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_CP042153.1|WP_000334463.1|2255028_2256834_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVVALATQENVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_CP042153.1|WP_000083807.1|2257514_2259053_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_CP042153.1|WP_000927371.1|2259087_2261220_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHSQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NZ_CP042153.1|WP_001292149.1|2261231_2261666_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA

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Crispr_ID: NZ_CP042153_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042153_10

2263395-2263480

Orphan

Consensus_repeat	Method
CCAACTGATTTTTGCGTATCATTAGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042153_10

>merge|NZ_CP042153|10|2263395-2263480|CRISPRCasFinder
CCAACTGATTTTTGCGTATCATTAGTTTGCATATCTTTAGCTTTATTGTTTGCAACTGGGCCAACTGATTTTTGCGTATCATTAGT

>NZ_CP042153|10|9|2263395-2263480|CRISPRCasFinder
CCAACTGATTTTTGCGTATCATTAGT	TTGCATATCTTTAGCTTTATTGTTTGCAACTGGG
CCAACTGATTTTTGCGTATCATTAGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042153.1\|WP_001792784.1\|2252273_2252432_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000047255.1\|2286386_2287070_-\|hemolysin-III-family-protein	unknown	unknown	gnl\|CDD\|224191
NZ_CP042153.1\|WP_000521495.1\|2270813_2272169_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NZ_CP042153.1\|WP_145373888.1\|2274127_2275033_-\|arginase	unknown	unknown	gnl\|CDD\|212515
NZ_CP042153.1\|WP_001141007.1\|2282529_2283972_-\|multidrug-efflux-MFS-transporter-LmrS	unknown	unknown	gnl\|CDD\|129794
NZ_CP042153.1\|WP_001292149.1\|2261231_2261666_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_CP042153.1\|WP_000636857.1\|2284294_2284768_-\|multidrug-efflux-transporter-SepA	unknown	unknown	gnl\|CDD\|374975
NZ_CP042153.1\|WP_001792291.1\|2252026_2252209_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_001794441.1\|2252868_2252961_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000927371.1\|2259087_2261220_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP042153.1\|WP_000884735.1\|2287088_2288276_-\|UDPGP-type-1-family-protein	unknown	unknown	gnl\|CDD\|133036
NZ_CP042153.1\|WP_000648741.1\|2261665_2262772_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_CP042153.1\|WP_000334463.1\|2255028_2256834_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP042153.1\|WP_000958531.1\|2281317_2282382_-\|P-loop-NTPase	unknown	unknown	gnl\|CDD\|378455
NZ_CP042153.1\|WP_000347896.1\|2273129_2273939_-\|TIGR00159-family-protein	unknown	unknown	gnl\|CDD\|224539
NZ_CP042153.1\|WP_001237506.1\|2284866_2286210_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP042153.1\|WP_000083807.1\|2257514_2259053_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP042153.1\|WP_000894032.1\|2272195_2273128_-\|YbbR-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|227193
NZ_CP042153.1\|WP_000370925.1\|2253089_2253947_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_CP042153.1\|WP_000908182.1\|2254014_2254797_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044

Protein	Function_ID	Function_description	E-value
NZ_CP042153.1\|WP_000047255.1\|2286386_2287070_-\|hemolysin-III-family-protein	gnl\|CDD\|224191	COG1272, COG1272, Predicted membrane protein, hemolysin III homolog [General function prediction only].	2.41003e-66
NZ_CP042153.1\|WP_000521495.1\|2270813_2272169_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NZ_CP042153.1\|WP_145373888.1\|2274127_2275033_-\|arginase	gnl\|CDD\|212515	cd09989, Arginase, Arginase family. This family includes arginase, also known as arginase-like amidino hydrolase family, and related proteins. Arginase is a binuclear Mn-dependent metalloenzyme and catalyzes hydrolysis of L-arginine to L-ornithine and urea (Arg, EC 3.5.3.1), the reaction being the fifth and final step in the urea cycle, providing the path for the disposal of nitrogenous compounds. Arginase controls cellular levels of arginine and ornithine which are involved in protein biosynthesis, and in production of creatine, polyamines, proline and nitric acid. In vertebrates, at least two isozymes have been identified: type I (ARG1) cytoplasmic or hepatic liver-type arginase and type II (ARG2) mitochondrial or non-hepatic arginase. Point mutations in human arginase ARG1 gene lead to hyperargininemia with consequent mental disorders, retarded development and early death. Hyperargininemia is associated with a several-fold increase in the activity of the mitochondrial arginase (ARG2), causing persistent ureagenesis in patients. ARG2 overexpression plays a critical role in the pathophysiology of cholesterol mediated endothelial dysfunction. Thus, arginase is a therapeutic target to treat asthma, erectile dysfunction, atherosclerosis and cancer.	6.77239e-145
NZ_CP042153.1\|WP_001141007.1\|2282529_2283972_-\|multidrug-efflux-MFS-transporter-LmrS	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.85929e-81
NZ_CP042153.1\|WP_001292149.1\|2261231_2261666_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_CP042153.1\|WP_000636857.1\|2284294_2284768_-\|multidrug-efflux-transporter-SepA	gnl\|CDD\|374975	pfam17080, SepA, Multidrug Resistance efflux pump. SepA is a drug efflux protein that is involved in bacterial multidrug resistance. It is predicted to have four transmembrane domains.	3.20059e-30
NZ_CP042153.1\|WP_000927371.1\|2259087_2261220_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.02509e-68
NZ_CP042153.1\|WP_000884735.1\|2287088_2288276_-\|UDPGP-type-1-family-protein	gnl\|CDD\|133036	cd04193, UDPGlcNAc_PPase, UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc) pyrophosphorylase (UAP) (also named GlcNAc1P uridyltransferase), catalyzes the reversible conversion of UTP and GlcNAc1 to PPi and UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc), the activated form of GlcNAc, is a key precursor of N- and O-linked glycosylations. It is essential for the synthesis of chitin (a major component of the fungal cell wall) and of the glycosylphosphatidylinositol (GPI) linker which anchors a variety of cell surface proteins to the plasma membrane. In bacteria, UDPGlcNAc represents an essential precursor for both peptidoglycan and lipopolysaccharide biosynthesis. Human UAP has two isoforms, resulting from alternative splicing of a single gene and differing by the presence or absence of 17 amino acids. UDPGlcNAc pyrophosphorylase shares significant sequence and structure conservation with UDPglucose pyrophosphorylase.	2.43588e-149
NZ_CP042153.1\|WP_000648741.1\|2261665_2262772_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_CP042153.1\|WP_000334463.1\|2255028_2256834_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP042153.1\|WP_000958531.1\|2281317_2282382_-\|P-loop-NTPase	gnl\|CDD\|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	6.43129e-115
NZ_CP042153.1\|WP_000347896.1\|2273129_2273939_-\|TIGR00159-family-protein	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	2.13611e-103
NZ_CP042153.1\|WP_001237506.1\|2284866_2286210_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	2.92638e-43
NZ_CP042153.1\|WP_000083807.1\|2257514_2259053_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_CP042153.1\|WP_000894032.1\|2272195_2273128_-\|YbbR-like-domain-containing-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	6.26423e-118
NZ_CP042153.1\|WP_000370925.1\|2253089_2253947_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	6.8047e-59
NZ_CP042153.1\|WP_000908182.1\|2254014_2254797_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	1.29094e-106

>NZ_CP042153.1|WP_000648741.1|2261665_2262772_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILTDNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NZ_CP042153.1|WP_001292149.1|2261231_2261666_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_CP042153.1|WP_000927371.1|2259087_2261220_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHSQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NZ_CP042153.1|WP_000083807.1|2257514_2259053_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_CP042153.1|WP_000334463.1|2255028_2256834_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVVALATQENVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_CP042153.1|WP_000908182.1|2254014_2254797_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKNISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATTGGVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEVRNEAHHLLKLVGISAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLNILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_CP042153.1|WP_000370925.1|2253089_2253947_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>NZ_CP042153.1|WP_001794441.1|2252868_2252961_+|hypothetical-protein
MTYGSIVAILCALFVIFFIPYMEKKDKKKK
>NZ_CP042153.1|WP_001792784.1|2252273_2252432_+|hypothetical-protein
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>NZ_CP042153.1|WP_001792291.1|2252026_2252209_-|hypothetical-protein
MIIFRFKVNAFFPVKLCLMIRFCLESCCIFRRHLLITFHNIRSKFIMFKYISSKCIICTG
>NZ_CP042153.1|WP_000521495.1|2270813_2272169_-|phosphoglucosamine-mutase
MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
>NZ_CP042153.1|WP_000894032.1|2272195_2273128_-|YbbR-like-domain-containing-protein
MLESKWGLRFIAFLLALFFFLSVNNVFGNIFNTGNLGQKSSKTIQDVPVEILYNTKDLHLTKAPETVNVTISGPQSKIIKIENPEDLRVVIDLSNAKAGKYQEKYQVKGLADDIHYSVKPKLANITLENKVTKKMTVQPDVSQSDIDPLYKITKQEVSPQTVKVTGGEEQLNDIAYLKATFKTNKKINGDTKDVAEVTAFDKKLNKLNVSIQPNEVNLQVKVEPFSKKVKVNVKQKGSLADDKELSSIDLEDKEIEIFGSRDDLQNISEVDAEVDLDGISESTEKTVKINLPEHVTKAQPSETKAYINVK
>NZ_CP042153.1|WP_000347896.1|2273129_2273939_-|TIGR00159-family-protein
MDFSNFFQNLSTLKIVTSILDLLIVWYVLYLLITVFKGTKAIQLLKGILVIVIGQQISMILNLTATSKLFDIVIQWGVLALIVIFQPEIRRALEQLGRGSFLKRYTSNTYSKDEEKLIQSVSKAVQYMAKRRIGALIVFEKETGLQDYIETGIAMDSNISQELLINVFIPNTPLHDGAMIIQGTKIAAAASYLPLSDSPKISKSLGTRHRAAVGISEVSDAFTVIVSEETGDISVTFDGKLRRDISNEIFEELLAEHWFGTRFQKKGVK
>NZ_CP042153.1|WP_145373888.1|2274127_2275033_-|arginase
MKTKAIDIIGAPSTFGQRKLGVDLGPTAIRYAGLISRLKQLDLDVYDKGDIKVPAVNIEKFHSEQKGLRNYDEIIDVNQKLNKEVSASIENNRFPLVLGGDHSIAVGSVSAISKHYNNLGIIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLELNSNVIKPENIVLIGMRDLDKGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKSRNVDGVHLSLDVDALDPLETPGTGTRVLGGLSYRESHFALELLHQSHLISSMDLVEVNPLIDSNNHTAEQAVSLVGTFFGETLL
>NZ_CP042153.1|WP_000958531.1|2281317_2282382_-|P-loop-NTPase
MLTVDQVKELVGEIKDPIIDVPLKETEGIVEVSIKEEKEHVSVKLAMAQLGGAPQLDLQMAVVNALKENGAKTVGIRFETLPEEKVNQFKPKEENKPKTIEGLLSQNNPVEFIAIASGKGGVGKSTVAVNLAVALAREGKKVGLVDADIYGFSVPDMMGIDEKPGIKGKEVIPVERHGVKVISMAFFVEENAPVIWRGPMLGKMLTNFFTEVKWGDIEYLILDLPPGTGDVALDVHTMLPSSKEIIVTTPHPTAAFVAARAGAMAKHTDHSILGVIENMSYFESKETGNKEYVFGKGGGTKLADELNTQLLGELPLEQPSWNPKDFAPSIYQSDDRLGKIYSSIAQKVIAATNK
>NZ_CP042153.1|WP_001141007.1|2282529_2283972_-|multidrug-efflux-MFS-transporter-LmrS
MAKVELTTRRRNFIVAVMLISAFVAILNQTLLNTALPSIMRELNINESTSQWLVTGFMLVNGVMIPLTAYLMDRIKTRPLYLAAMGTFLLGSIVAALAPNFGVLMLARVIQAMGAGVLMPLMQFTLFTLFSKEHRGFAMGLAGLVIQFAPAIGPTVTGLIIDQASWRVPFIIIVGIALVAFVFGLVSISSYNEVKYTKLDKRSVMYSTIGFGLMLYAFSSAGDLGFTSPIVIGALIISMVIIYLFIRRQFNITNVLLNLRVFKNRTFALCTISSMIIMMSMVGPALLIPLYVQNSLSLSALLSGLVIMPGAIINGIMSVFTGKFYDKYGPRPLIYTGFTILTITTIMLCFLHTDTSYTYLIVVYAIRMFSVSLLMMPINTTGINSLRNEEISHGTAIMNFGRVMAGSLGTALMVTLMSFGAKIFLSTSPSHLTATEIKQQSIAIGVDISFAFVAVLVMAAYVIALFIREPKEIESNRRKF
>NZ_CP042153.1|WP_000636857.1|2284294_2284768_-|multidrug-efflux-transporter-SepA
MIVNYLKHKFYNLLTTMIVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIIFAVEHLMDYFRKMLPENAYFRGATFHLISYTVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
>NZ_CP042153.1|WP_001237506.1|2284866_2286210_-|MFS-transporter
MRLKSIITVIALILIMFMSAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPIVGELLSRFKIIYVAIAGLLLFSIGSFMCGLSTNFTMLIISRVIQGFGSGVLMSLSQIVPKLAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWHWLFYINIPIAIIAIILVIWTFHFPEEETVAKSKFDTKGLTLFYVFIGLIMFALLNQQLLLLNFLSFILAIVVAMCLFKVEKHVSSPFLPVVEFNRSITLVFITDLLTAICLMGFNLYIPVYLQEQLGLSPLQSGLVIFPLSVAWITLNFNLHRIEAKLSRKVIYLLSFTLLLVSSIIISFGIKLPVLIAFVLILAGLSFGYIYTKDSVIVQEETSPLQMKKMMSFYGLTKNLGASIGSTIMGYLYAIQSGIFGPNLHNVLSAVAVISIGLIVLWVVFFKEQSSQSKE
>NZ_CP042153.1|WP_000047255.1|2286386_2287070_-|hemolysin-III-family-protein
MSKSTKKSNDTIVETFKDIIPLSFGEEIGNAASHGVAALLTLLVLPYAAVHSYIAHGTLASVSMSIYVISIFMMFISSTIYHSMQNETPHKYILRIIDHSMIYVAISGTYTPILLTVVGGWIGWTVFILLWGTTLWGILYKSIAVKVNQKLSLIVYLVMGWVGIILLPIIFIRTSWIFILFIFLGGVSYTIGAWFYAQKNRPYFHMIWHIFIVIASLLHLIAILYFM
>NZ_CP042153.1|WP_000884735.1|2287088_2288276_-|UDPGP-type-1-family-protein
MLDKNQLAKYKQDHLCEYEKIMSNNEKEALEEKVASLDLDFIAKLYNDLYINKKTIDDVSAVSEVKYDIKSQMSDDEIKRLEEQGLQAIKEGQFAVLLMAGGQGTRLGYKGPKGSFEIEGVSLFELQANQLKTLNHQSGHTIQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMETPNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVKVLDPLFAGFTVEHDYDITSKTIQPKPGESVGRLVNVDCKDTVLEYSELDPEVANQFNNANIGIHAFKLGFILNAVNRELPYHLAIKNLKQLDENFGVIEQPTLKFELFYFDIFTYGTSFVTLQVPREEEFSPLKNKEGKDSVATATEDLRRMGLI

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Crispr_ID: NZ_CP042153_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042153_11

2371479-2371559

Orphan

Consensus_repeat	Method
TCTATGTTGGGGCCCCGCCAACTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042153_11

>merge|NZ_CP042153|11|2371479-2371559|CRISPRCasFinder
TCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTTCTGTCAGCTTCTGTGTTGGGGCCCCGCCAACTTG

>NZ_CP042153|11|10|2371479-2371559|CRISPRCasFinder
TCTATGTTGGGGCCCCGCCAACTTG	CACATTATTGTAAGCTGACTTTCTGTCAGCT
TCTGTGTTGGGGCCCCGCCAACTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042153.1\|WP_001792132.1\|2371251_2371437_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000259717.1\|2374531_2375791_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NZ_CP042153.1\|WP_000951058.1\|2369029_2369470_+\|winged-helix-DNA-binding-protein	unknown	unknown	gnl\|CDD\|197670
NZ_CP042153.1\|WP_000076930.1\|2376886_2377891_-\|molybdopterin-biosynthesis-protein-MoeB	unknown	unknown	gnl\|CDD\|181084
NZ_CP042153.1\|WP_000866971.1\|2373350_2373584_-\|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl\|CDD\|340452
NZ_CP042153.1\|WP_000643986.1\|2372744_2373344_-\|molybdenum-cofactor-guanylyltransferase-MobA	unknown	unknown	gnl\|CDD\|234725
NZ_CP042153.1\|WP_000051210.1\|2362012_2362177_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000808495.1\|2373589_2374036_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|223391
NZ_CP042153.1\|WP_000913024.1\|2378060_2378666_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226628
NZ_CP042153.1\|WP_000139181.1\|2360971_2361880_-\|AEC-family-transporter	unknown	unknown	gnl\|CDD\|223751
NZ_CP042153.1\|WP_001161085.1\|2362421_2362739_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_000184404.1\|2369462_2370674_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NZ_CP042153.1\|WP_000066900.1\|2370775_2371126_-\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
NZ_CP042153.1\|WP_000600967.1\|2368103_2368868_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
NZ_CP042153.1\|WP_000134526.1\|2375853_2376348_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NZ_CP042153.1\|WP_000230173.1\|2371702_2372725_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NZ_CP042153.1\|WP_000413862.1\|2366206_2367472_-\|lipid-II:glycine-glycyltransferase-FemX	unknown	unknown	gnl\|CDD\|225224
NZ_CP042153.1\|WP_001549681.1\|2367860_2368112_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042153.1\|WP_114306668.1\|2376349_2376856_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	unknown	unknown	gnl\|CDD\|223595
NZ_CP042153.1\|WP_000602950.1\|2374049_2374535_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677

Protein	Function_ID	Function_description	E-value
NZ_CP042153.1\|WP_000259717.1\|2374531_2375791_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	4.50966e-159
NZ_CP042153.1\|WP_000951058.1\|2369029_2369470_+\|winged-helix-DNA-binding-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.35323e-15
NZ_CP042153.1\|WP_000076930.1\|2376886_2377891_-\|molybdopterin-biosynthesis-protein-MoeB	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	6.83722e-133
NZ_CP042153.1\|WP_000866971.1\|2373350_2373584_-\|molybdopterin-converting-factor-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	8.16473e-25
NZ_CP042153.1\|WP_000643986.1\|2372744_2373344_-\|molybdenum-cofactor-guanylyltransferase-MobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	2.15389e-66
NZ_CP042153.1\|WP_114306668.1\|2376349_2376856_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	4.0236e-64
NZ_CP042153.1\|WP_000913024.1\|2378060_2378666_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	1.78595e-116
NZ_CP042153.1\|WP_000139181.1\|2360971_2361880_-\|AEC-family-transporter	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	7.28102e-43
NZ_CP042153.1\|WP_000808495.1\|2373589_2374036_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	6.99133e-58
NZ_CP042153.1\|WP_000184404.1\|2369462_2370674_+\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.92881e-73
NZ_CP042153.1\|WP_000066900.1\|2370775_2371126_-\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
NZ_CP042153.1\|WP_000600967.1\|2368103_2368868_-\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	1.50083e-38
NZ_CP042153.1\|WP_000134526.1\|2375853_2376348_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	2.93711e-97
NZ_CP042153.1\|WP_000230173.1\|2371702_2372725_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
NZ_CP042153.1\|WP_000413862.1\|2366206_2367472_-\|lipid-II:glycine-glycyltransferase-FemX	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	1.81413e-143
NZ_CP042153.1\|WP_000602950.1\|2374049_2374535_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	9.59347e-51

>NZ_CP042153.1|WP_001792132.1|2371251_2371437_+|hypothetical-protein
MFRFISFGQLVVYSTTFIPKKDILQLNDLECDINVKEPLKINYVVIFGSGTEITFSQNLFR
>NZ_CP042153.1|WP_000066900.1|2370775_2371126_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>NZ_CP042153.1|WP_000184404.1|2369462_2370674_+|MFS-transporter
MTNQGSLNKSPIFTKSFTINFFVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETDVINKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>NZ_CP042153.1|WP_000951058.1|2369029_2369470_+|winged-helix-DNA-binding-protein
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>NZ_CP042153.1|WP_000600967.1|2368103_2368868_-|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKNKLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>NZ_CP042153.1|WP_001549681.1|2367860_2368112_+|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLVIIHMGILAHSTYVYLY
>NZ_CP042153.1|WP_000413862.1|2366206_2367472_-|lipid-II:glycine-glycyltransferase-FemX
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYILNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>NZ_CP042153.1|WP_001161085.1|2362421_2362739_+|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>NZ_CP042153.1|WP_000051210.1|2362012_2362177_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDLEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>NZ_CP042153.1|WP_000139181.1|2360971_2361880_-|AEC-family-transporter
MTEQFTMIILLIALGYFLKRINFIKATDSQVIATLVLNVTLPSLVIVNLNSAELKLSFSILPILMIIYGIVAKMIAVWFFRKYDNHMRGSVGMMTGAMNIGLFAYPLIEVIWPKTGLIYFGMADIGGAFVMFGITYFVGSYFSEGSDQFDFKYLGKKLLQSVPLVTYIVMFILNINHIHLPHVAIDFFSILSHANMPLSMILLGVMLNFTLERKYIPATIKYLCLHYGLALVAGLLVHVLLPVSDDMIKTTLLVTWMFPVGVAIISYGIQFKYRTLPFIGMTTNLTIIISIIILYVYQAVFV
>NZ_CP042153.1|WP_000230173.1|2371702_2372725_-|GTP-3',8-cyclase-MoaA
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>NZ_CP042153.1|WP_000643986.1|2372744_2373344_-|molybdenum-cofactor-guanylyltransferase-MobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNIYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>NZ_CP042153.1|WP_000866971.1|2373350_2373584_-|molybdopterin-converting-factor-subunit-1
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>NZ_CP042153.1|WP_000808495.1|2373589_2374036_-|molybdenum-cofactor-biosynthesis-protein-MoaE
MKQFEIVIEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>NZ_CP042153.1|WP_000602950.1|2374049_2374535_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKTHGYTVATIKHHGHAKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRDEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>NZ_CP042153.1|WP_000259717.1|2374531_2375791_-|molybdopterin-molybdotransferase-MoeA
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFADGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>NZ_CP042153.1|WP_000134526.1|2375853_2376348_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSGQ
>NZ_CP042153.1|WP_114306668.1|2376349_2376856_-|molybdenum-cofactor-biosynthesis-protein-MoaB
MGEHQNVKLNRTVKAAVLTVSDTRDFVTDKGGQCVSQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>NZ_CP042153.1|WP_000076930.1|2376886_2377891_-|molybdopterin-biosynthesis-protein-MoeB
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDGCIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>NZ_CP042153.1|WP_000913024.1|2378060_2378666_-|ATP-binding-cassette-domain-containing-protein
MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTTKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSKHIDQLIQTLNINHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP042153_2	2.1\|597496\|57\|NZ_CP042153\|CRISPRCasFinder	597496-597552	57	NZ_CP042153.1	1972338-1972394	0	1.0
NZ_CP042153_4	4.1\|861574\|31\|NZ_CP042153\|CRISPRCasFinder	861574-861604	31	NZ_CP042153.1	341121-341151	0	1.0
NZ_CP042153_5	5.1\|867041\|25\|NZ_CP042153\|CRISPRCasFinder	867041-867065	25	NZ_CP042153.1	218091-218115	0	1.0
NZ_CP042153_5	5.1\|867041\|25\|NZ_CP042153\|CRISPRCasFinder	867041-867065	25	NZ_CP042153.1	218149-218173	0	1.0
NZ_CP042153_5	5.1\|867041\|25\|NZ_CP042153\|CRISPRCasFinder	867041-867065	25	NZ_CP042153.1	341043-341067	0	1.0
NZ_CP042153_5	5.1\|867041\|25\|NZ_CP042153\|CRISPRCasFinder	867041-867065	25	NZ_CP042153.1	341153-341177	0	1.0
NZ_CP042153_5	5.1\|867041\|25\|NZ_CP042153\|CRISPRCasFinder	867041-867065	25	NZ_CP042153.1	696784-696808	0	1.0
NZ_CP042153_5	5.1\|867041\|25\|NZ_CP042153\|CRISPRCasFinder	867041-867065	25	NZ_CP042153.1	1404231-1404255	0	1.0
NZ_CP042153_5	5.1\|867041\|25\|NZ_CP042153\|CRISPRCasFinder	867041-867065	25	NZ_CP042153.1	1690181-1690205	0	1.0
NZ_CP042153_5	5.1\|867041\|25\|NZ_CP042153\|CRISPRCasFinder	867041-867065	25	NZ_CP042153.1	819642-819666	0	1.0
NZ_CP042153_5	5.1\|867041\|25\|NZ_CP042153\|CRISPRCasFinder	867041-867065	25	NZ_CP042153.1	910496-910520	0	1.0
NZ_CP042153_5	5.1\|867041\|25\|NZ_CP042153\|CRISPRCasFinder	867041-867065	25	NZ_CP042153.1	1675650-1675674	0	1.0
NZ_CP042153_5	5.1\|867041\|25\|NZ_CP042153\|CRISPRCasFinder	867041-867065	25	NZ_CP042153.1	2015681-2015705	0	1.0
NZ_CP042153_4	4.1\|861574\|31\|NZ_CP042153\|CRISPRCasFinder	861574-861604	31	NZ_CP042153.1	341066-341096	1	0.968
NZ_CP042153_4	4.1\|861574\|31\|NZ_CP042153\|CRISPRCasFinder	861574-861604	31	NZ_CP042153.1	1709926-1709956	1	0.968
NZ_CP042153_5	5.1\|867041\|25\|NZ_CP042153\|CRISPRCasFinder	867041-867065	25	NZ_CP042153.1	341098-341122	1	0.96
NZ_CP042153_5	5.1\|867041\|25\|NZ_CP042153\|CRISPRCasFinder	867041-867065	25	NZ_CP042153.1	994768-994792	1	0.96
NZ_CP042153_5	5.1\|867041\|25\|NZ_CP042153\|CRISPRCasFinder	867041-867065	25	NZ_CP042153.1	1709900-1709924	1	0.96
NZ_CP042153_5	5.1\|867041\|25\|NZ_CP042153\|CRISPRCasFinder	867041-867065	25	NZ_CP042153.1	1710014-1710038	1	0.96
NZ_CP042153_6	6.1\|910447\|34\|NZ_CP042153\|CRISPRCasFinder	910447-910480	34	NZ_CP042153.1	1404330-1404363	1	0.971
NZ_CP042153_8	8.1\|1675600\|33\|NZ_CP042153\|CRISPRCasFinder	1675600-1675632	33	NZ_CP042153.1	218191-218223	1	0.97
NZ_CP042153_8	8.1\|1675600\|33\|NZ_CP042153\|CRISPRCasFinder	1675600-1675632	33	NZ_CP042153.1	1404331-1404363	1	0.97
NZ_CP042153_11	11.1\|2371504\|31\|NZ_CP042153\|CRISPRCasFinder	2371504-2371534	31	NZ_CP042153.1	874176-874206	1	0.968
NZ_CP042153_11	11.1\|2371504\|31\|NZ_CP042153\|CRISPRCasFinder	2371504-2371534	31	NZ_CP042153.1	874232-874262	1	0.968
NZ_CP042153_11	11.1\|2371504\|31\|NZ_CP042153\|CRISPRCasFinder	2371504-2371534	31	NZ_CP042153.1	122111-122141	2	0.935
NZ_CP042153_11	11.1\|2371504\|31\|NZ_CP042153\|CRISPRCasFinder	2371504-2371534	31	NZ_CP042153.1	874288-874318	2	0.935
NZ_CP042153_11	11.1\|2371504\|31\|NZ_CP042153\|CRISPRCasFinder	2371504-2371534	31	NZ_CP042153.1	910759-910789	2	0.935
NZ_CP042153_11	11.1\|2371504\|31\|NZ_CP042153\|CRISPRCasFinder	2371504-2371534	31	NZ_CP042153.1	1092284-1092314	2	0.935
NZ_CP042153_11	11.1\|2371504\|31\|NZ_CP042153\|CRISPRCasFinder	2371504-2371534	31	NZ_CP042153.1	1494243-1494273	2	0.935
NZ_CP042153_11	11.1\|2371504\|31\|NZ_CP042153\|CRISPRCasFinder	2371504-2371534	31	NZ_CP042153.1	2014333-2014363	2	0.935
NZ_CP042153_11	11.1\|2371504\|31\|NZ_CP042153\|CRISPRCasFinder	2371504-2371534	31	NZ_CP042153.1	2360703-2360733	2	0.935
NZ_CP042153_11	11.1\|2371504\|31\|NZ_CP042153\|CRISPRCasFinder	2371504-2371534	31	NZ_CP042153.1	2536529-2536559	2	0.935
NZ_CP042153_11	11.1\|2371504\|31\|NZ_CP042153\|CRISPRCasFinder	2371504-2371534	31	NZ_CP042153.1	417493-417523	2	0.935
NZ_CP042153_11	11.1\|2371504\|31\|NZ_CP042153\|CRISPRCasFinder	2371504-2371534	31	NZ_CP042153.1	696842-696872	2	0.935
NZ_CP042153_11	11.1\|2371504\|31\|NZ_CP042153\|CRISPRCasFinder	2371504-2371534	31	NZ_CP042153.1	1198194-1198224	2	0.935
NZ_CP042153_11	11.1\|2371504\|31\|NZ_CP042153\|CRISPRCasFinder	2371504-2371534	31	NZ_CP042153.1	1404289-1404319	2	0.935
NZ_CP042153_11	11.1\|2371504\|31\|NZ_CP042153\|CRISPRCasFinder	2371504-2371534	31	NZ_CP042153.1	1690238-1690268	2	0.935

1. spacer 2.1|597496|57|NZ_CP042153|CRISPRCasFinder matches to position: 1972338-1972394, mismatch: 0, identity: 1.0

atttaatacctatttgggggcttagctcagctgggagagcgcctgctttgcacgcag	CRISPR spacer
atttaatacctatttgggggcttagctcagctgggagagcgcctgctttgcacgcag	Protospacer
*********************************************************

2. spacer 4.1|861574|31|NZ_CP042153|CRISPRCasFinder matches to position: 341121-341151, mismatch: 0, identity: 1.0

ctgtgttggggccccgccaacttgcattgcc	CRISPR spacer
ctgtgttggggccccgccaacttgcattgcc	Protospacer
*******************************

3. spacer 5.1|867041|25|NZ_CP042153|CRISPRCasFinder matches to position: 218091-218115, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

4. spacer 5.1|867041|25|NZ_CP042153|CRISPRCasFinder matches to position: 218149-218173, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

5. spacer 5.1|867041|25|NZ_CP042153|CRISPRCasFinder matches to position: 341043-341067, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

6. spacer 5.1|867041|25|NZ_CP042153|CRISPRCasFinder matches to position: 341153-341177, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

7. spacer 5.1|867041|25|NZ_CP042153|CRISPRCasFinder matches to position: 696784-696808, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

8. spacer 5.1|867041|25|NZ_CP042153|CRISPRCasFinder matches to position: 1404231-1404255, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

9. spacer 5.1|867041|25|NZ_CP042153|CRISPRCasFinder matches to position: 1690181-1690205, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

10. spacer 5.1|867041|25|NZ_CP042153|CRISPRCasFinder matches to position: 819642-819666, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

11. spacer 5.1|867041|25|NZ_CP042153|CRISPRCasFinder matches to position: 910496-910520, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

12. spacer 5.1|867041|25|NZ_CP042153|CRISPRCasFinder matches to position: 1675650-1675674, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

13. spacer 5.1|867041|25|NZ_CP042153|CRISPRCasFinder matches to position: 2015681-2015705, mismatch: 0, identity: 1.0

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaaattc	Protospacer
*************************

14. spacer 4.1|861574|31|NZ_CP042153|CRISPRCasFinder matches to position: 341066-341096, mismatch: 1, identity: 0.968

ctgtgttggggccccgccaacttgcattgcc	CRISPR spacer
ctgtgttggggccccgccaacttgcattacc	Protospacer
****************************.**

15. spacer 4.1|861574|31|NZ_CP042153|CRISPRCasFinder matches to position: 1709926-1709956, mismatch: 1, identity: 0.968

ctgtgttggggccccgccaacttgcattgcc	CRISPR spacer
ctgtgttggggccccgccaacttccattgcc	Protospacer
*********************** *******

16. spacer 5.1|867041|25|NZ_CP042153|CRISPRCasFinder matches to position: 341098-341122, mismatch: 1, identity: 0.96

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttcgaatttc	Protospacer
********************* ***

17. spacer 5.1|867041|25|NZ_CP042153|CRISPRCasFinder matches to position: 994768-994792, mismatch: 1, identity: 0.96

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttcttttagaaattc	Protospacer
***************** *******

18. spacer 5.1|867041|25|NZ_CP042153|CRISPRCasFinder matches to position: 1709900-1709924, mismatch: 1, identity: 0.96

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttctttacgaaattc	Protospacer
**************** ********

19. spacer 5.1|867041|25|NZ_CP042153|CRISPRCasFinder matches to position: 1710014-1710038, mismatch: 1, identity: 0.96

cctgtagaatttcttttcgaaattc	CRISPR spacer
cctgtagaatttctttacgaaattc	Protospacer
**************** ********

20. spacer 6.1|910447|34|NZ_CP042153|CRISPRCasFinder matches to position: 1404330-1404363, mismatch: 1, identity: 0.971

attgagaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
****.*****************************

21. spacer 8.1|1675600|33|NZ_CP042153|CRISPRCasFinder matches to position: 218191-218223, mismatch: 1, identity: 0.97

attgggaatccaatttctctgtgttggggccca	CRISPR spacer
attgggaatccaatttctctttgttggggccca	Protospacer
******************** ************

22. spacer 8.1|1675600|33|NZ_CP042153|CRISPRCasFinder matches to position: 1404331-1404363, mismatch: 1, identity: 0.97

attgggaatccaatttctctgtgttggggccca	CRISPR spacer
attgggaatccaatttctctttgttggggccca	Protospacer
******************** ************

23. spacer 11.1|2371504|31|NZ_CP042153|CRISPRCasFinder matches to position: 874176-874206, mismatch: 1, identity: 0.968

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgtcagct	Protospacer
***********************.*******

24. spacer 11.1|2371504|31|NZ_CP042153|CRISPRCasFinder matches to position: 874232-874262, mismatch: 1, identity: 0.968

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgtcagct	Protospacer
***********************.*******

25. spacer 11.1|2371504|31|NZ_CP042153|CRISPRCasFinder matches to position: 122111-122141, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

26. spacer 11.1|2371504|31|NZ_CP042153|CRISPRCasFinder matches to position: 874288-874318, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

27. spacer 11.1|2371504|31|NZ_CP042153|CRISPRCasFinder matches to position: 910759-910789, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

28. spacer 11.1|2371504|31|NZ_CP042153|CRISPRCasFinder matches to position: 1092284-1092314, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

29. spacer 11.1|2371504|31|NZ_CP042153|CRISPRCasFinder matches to position: 1494243-1494273, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

30. spacer 11.1|2371504|31|NZ_CP042153|CRISPRCasFinder matches to position: 2014333-2014363, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

31. spacer 11.1|2371504|31|NZ_CP042153|CRISPRCasFinder matches to position: 2360703-2360733, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

32. spacer 11.1|2371504|31|NZ_CP042153|CRISPRCasFinder matches to position: 2536529-2536559, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

33. spacer 11.1|2371504|31|NZ_CP042153|CRISPRCasFinder matches to position: 417493-417523, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

34. spacer 11.1|2371504|31|NZ_CP042153|CRISPRCasFinder matches to position: 696842-696872, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

35. spacer 11.1|2371504|31|NZ_CP042153|CRISPRCasFinder matches to position: 1198194-1198224, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

36. spacer 11.1|2371504|31|NZ_CP042153|CRISPRCasFinder matches to position: 1404289-1404319, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

37. spacer 11.1|2371504|31|NZ_CP042153|CRISPRCasFinder matches to position: 1690238-1690268, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP042153_2	2.1\|597496\|57\|NZ_CP042153\|CRISPRCasFinder	597496-597552	57	NZ_CP033045	Bacillus foraminis strain Bac44 plasmid unnamed, complete sequence	484751-484807	7	0.877
NZ_CP042153_10	10.1\|2263421\|34\|NZ_CP042153\|CRISPRCasFinder	2263421-2263454	34	JN882286	Cronobacter phage vB_CsaP_GAP52, complete genome	23034-23067	8	0.765
NZ_CP042153_10	10.1\|2263421\|34\|NZ_CP042153\|CRISPRCasFinder	2263421-2263454	34	CP030544	Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence	7567-7600	8	0.765
NZ_CP042153_2	2.1\|597496\|57\|NZ_CP042153\|CRISPRCasFinder	597496-597552	57	NZ_CP015440	Anoxybacillus amylolyticus strain DSM 15939 plasmid pDSM15939_2, complete sequence	1247-1303	11	0.807
NZ_CP042153_2	2.1\|597496\|57\|NZ_CP042153\|CRISPRCasFinder	597496-597552	57	NZ_CP041068	Bacillus megaterium strain KNU-01 plasmid pKNU_01_4, complete sequence	36469-36525	11	0.807
NZ_CP042153_2	2.1\|597496\|57\|NZ_CP042153\|CRISPRCasFinder	597496-597552	57	CP041516	Bacillus aryabhattai strain KNU10 plasmid unnamed, complete sequence	17595-17651	11	0.807
NZ_CP042153_2	2.1\|597496\|57\|NZ_CP042153\|CRISPRCasFinder	597496-597552	57	NZ_CP010587	Bacillus megaterium Q3 plasmid p1, complete sequence	1114-1170	17	0.702
NZ_CP042153_2	2.1\|597496\|57\|NZ_CP042153\|CRISPRCasFinder	597496-597552	57	NZ_CP023319	Bacillus megaterium strain A plasmid p2, complete sequence	76101-76157	17	0.702
NZ_CP042153_2	2.1\|597496\|57\|NZ_CP042153\|CRISPRCasFinder	597496-597552	57	NZ_CP024037	Bacillus aryabhattai strain K13 plasmid unnamed2	10145-10201	17	0.702
NZ_CP042153_2	2.1\|597496\|57\|NZ_CP042153\|CRISPRCasFinder	597496-597552	57	NZ_CP026740	Bacillus megaterium strain YC4-R4 plasmid unnamed4	70491-70547	17	0.702
NZ_CP042153_2	2.1\|597496\|57\|NZ_CP042153\|CRISPRCasFinder	597496-597552	57	NC_017139	Bacillus megaterium WSH-002 plasmid WSH-002_p1, complete sequence	1045-1101	17	0.702
NZ_CP042153_2	2.1\|597496\|57\|NZ_CP042153\|CRISPRCasFinder	597496-597552	57	NC_004604	Bacillus megaterium QM B1551 plasmid pBM400, complete sequence	46705-46761	18	0.684

1. spacer 2.1|597496|57|NZ_CP042153|CRISPRCasFinder matches to NZ_CP033045 (Bacillus foraminis strain Bac44 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.877

---atttaatacctatttgggggcttagctcagctgggagagcgcctgctttgcacgcag	CRISPR spacer
cgaatatattat---tttggggccttagctcagctgggagagcgcctgctttgcacgcag	Protospacer
   ** ** **.   ******* *************************************

2. spacer 10.1|2263421|34|NZ_CP042153|CRISPRCasFinder matches to JN882286 (Cronobacter phage vB_CsaP_GAP52, complete genome) position: , mismatch: 8, identity: 0.765

ttgcatatctttagctttattgtttgcaactggg	CRISPR spacer
ttgcatatctttagctttatagcttttatatgct	Protospacer
******************** *.** .*  **

3. spacer 10.1|2263421|34|NZ_CP042153|CRISPRCasFinder matches to CP030544 (Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.765

ttgcatatctttagctttattgtttgcaactggg	CRISPR spacer
ttgaataactttagctttattgttataaacagta	Protospacer
*** *** ****************   *** * .

4. spacer 2.1|597496|57|NZ_CP042153|CRISPRCasFinder matches to NZ_CP015440 (Anoxybacillus amylolyticus strain DSM 15939 plasmid pDSM15939_2, complete sequence) position: , mismatch: 11, identity: 0.807

atttaatacctatttgggggcttagctcagctgggagagcgcctgctttgcacgcag	CRISPR spacer
cagcagaatatgttcggggccttagctcagctgggagagcgcctgctttgcacgcag	Protospacer
   .*. *. *.**.**** *************************************

5. spacer 2.1|597496|57|NZ_CP042153|CRISPRCasFinder matches to NZ_CP041068 (Bacillus megaterium strain KNU-01 plasmid pKNU_01_4, complete sequence) position: , mismatch: 11, identity: 0.807

atttaatacctatt-tgggggcttagctcagctgggagagcgcctgctttgcacgcag	CRISPR spacer
-ccagagaagtatcatggggccttagctcagctgggagagcgcctgccttgcacgcag	Protospacer
 .. .* *  ***. ***** **************************.**********

6. spacer 2.1|597496|57|NZ_CP042153|CRISPRCasFinder matches to CP041516 (Bacillus aryabhattai strain KNU10 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.807

atttaatacctatt-tgggggcttagctcagctgggagagcgcctgctttgcacgcag	CRISPR spacer
-ccagagaagtatcatggggccttagctcagctgggagagcgcctgccttgcacgcag	Protospacer
 .. .* *  ***. ***** **************************.**********

7. spacer 2.1|597496|57|NZ_CP042153|CRISPRCasFinder matches to NZ_CP010587 (Bacillus megaterium Q3 plasmid p1, complete sequence) position: , mismatch: 17, identity: 0.702

---------atttaatacctatttgggggcttagctcagctgggagagcgcctgctttgc	CRISPR spacer
ttcccgaccattta---------tggggccttagctcagctgggagagcgcctgccttgc	Protospacer
         *****         ***** **************************.****

8. spacer 2.1|597496|57|NZ_CP042153|CRISPRCasFinder matches to NZ_CP023319 (Bacillus megaterium strain A plasmid p2, complete sequence) position: , mismatch: 17, identity: 0.702

---------atttaatacctatttgggggcttagctcagctgggagagcgcctgctttgc	CRISPR spacer
ttcccgaccattta---------tggggccttagctcagctgggagagcgcctgccttgc	Protospacer
         *****         ***** **************************.****

9. spacer 2.1|597496|57|NZ_CP042153|CRISPRCasFinder matches to NZ_CP024037 (Bacillus aryabhattai strain K13 plasmid unnamed2) position: , mismatch: 17, identity: 0.702

---------atttaatacctatttgggggcttagctcagctgggagagcgcctgctttgc	CRISPR spacer
ttcccgaccattta---------tggggccttagctcagctgggagagcgcctgccttgc	Protospacer
         *****         ***** **************************.****

10. spacer 2.1|597496|57|NZ_CP042153|CRISPRCasFinder matches to NZ_CP026740 (Bacillus megaterium strain YC4-R4 plasmid unnamed4) position: , mismatch: 17, identity: 0.702

---------atttaatacctatttgggggcttagctcagctgggagagcgcctgctttgc	CRISPR spacer
ttcccgaccattta---------tggggccttagctcagctgggagagcgcctgccttgc	Protospacer
         *****         ***** **************************.****

11. spacer 2.1|597496|57|NZ_CP042153|CRISPRCasFinder matches to NC_017139 (Bacillus megaterium WSH-002 plasmid WSH-002_p1, complete sequence) position: , mismatch: 17, identity: 0.702

---------atttaatacctatttgggggcttagctcagctgggagagcgcctgctttgc	CRISPR spacer
ttcccgaccattta---------tggggccttagctcagctgggagagcgcctgccttgc	Protospacer
         *****         ***** **************************.****

12. spacer 2.1|597496|57|NZ_CP042153|CRISPRCasFinder matches to NC_004604 (Bacillus megaterium QM B1551 plasmid pBM400, complete sequence) position: , mismatch: 18, identity: 0.684

---------atttaatacctatttgggggcttagctcagctgggagagcgcctgctttgc	CRISPR spacer
ttcccgaccactta---------tggggccttagctcagctgggagagcgcctgccttgc	Protospacer
         *.***         ***** **************************.****

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

440977 : 459403

Staphylococcus_phage(90.48%)

integrase,coat,terminase

attL 437702:437716|attR 452364:452378

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
437702:437716	attL	NA	NA	NA	NA
WP_001052484.1\|440977_441169_-	hypothetical protein	U3PCX8	Staphylococcus_phage	1.1e-22	80.0
WP_001261460.1\|441412_441709_+	30S ribosomal protein S6	NA	NA	NA	NA
WP_000934799.1\|441729_442233_+	single-stranded DNA-binding protein	A0A1W6JPL9	Staphylococcus_phage	1.2e-60	74.7
WP_000897044.1\|442284_442527_+	30S ribosomal protein S18	NA	NA	NA	NA
WP_031765313.1\|443667_444882_-\|integrase	site-specific integrase	Q4ZE80	Staphylococcus_phage	2.0e-218	95.8
WP_000668215.1\|445145_445871_-	helix-turn-helix transcriptional regulator	Q4ZE79	Staphylococcus_phage	3.1e-17	28.1
WP_001245562.1\|446042_446255_+	helix-turn-helix transcriptional regulator	Q4ZE78	Staphylococcus_phage	6.6e-29	87.1
WP_001138300.1\|446255_446528_+	winged helix-turn-helix domain-containing protein	Q4ZE77	Staphylococcus_phage	7.2e-44	94.4
WP_031795576.1\|446539_446686_+	hypothetical protein	NA	NA	NA	NA
WP_001058498.1\|446678_446891_+	hypothetical protein	A0A1W6JPA6	Staphylococcus_phage	1.4e-18	70.6
WP_001038250.1\|446892_447252_+	hypothetical protein	NA	NA	NA	NA
WP_001103969.1\|447252_447570_+	DUF1474 family protein	A0A1W6JQH0	Staphylococcus_phage	1.3e-33	84.1
WP_145411572.1\|447633_448503_+	mobile element-associated protein	A0A1W6JQL5	Staphylococcus_phage	3.1e-157	94.1
WP_031765320.1\|448519_449977_+	virulence-associated protein E	A0A1W6JQD6	Staphylococcus_phage	3.5e-278	96.5
WP_031765322.1\|450277_450640_+	hypothetical protein	A0A1W6JQD5	Staphylococcus_phage	6.0e-62	94.2
WP_000998179.1\|450641_450926_+	hypothetical protein	A0A1W6JQE4	Staphylococcus_phage	1.2e-49	100.0
WP_031765326.1\|450922_451564_+	pathogenicity island protein	Q4ZE67	Staphylococcus_phage	4.5e-105	88.3
WP_001288441.1\|452271_452616_+	hypothetical protein	A0A1W6JQF3	Staphylococcus_phage	1.4e-57	100.0
452364:452378	attR	NA	NA	NA	NA
WP_031769358.1\|452650_453229_+	hypothetical protein	A0A1W6JQG0	Staphylococcus_phage	9.2e-81	100.0
WP_031765331.1\|453457_453985_+\|coat	spore coat protein	A0A1W6JQH7	Staphylococcus_phage	4.3e-85	95.4
WP_031769360.1\|453987_454329_+	hypothetical protein	A0A1W6JQM3	Staphylococcus_phage	4.9e-58	99.1
WP_031765334.1\|454325_454895_+\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	3.0e-100	96.8
WP_001035599.1\|455049_455754_-	toxic shock syndrome toxin TSST-1	NA	NA	NA	NA
WP_031765336.1\|456684_457242_-	DUF4888 domain-containing protein	A0A1W6JQE5	Staphylococcus_phage	1.7e-63	69.4
WP_000273396.1\|457800_458220_+	hypothetical protein	Q9MBN1	Staphylococcus_prophage	8.7e-81	100.0
WP_001606776.1\|458233_459403_+	hypothetical protein	Q9MBN0	Staphylococcus_prophage	1.6e-212	99.5

DBSCAN-SWA_2

798720 : 806541

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000244415.1\|798720_799776_-	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
WP_000149344.1\|799775_800462_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037807.1\|800436_800910_-	DoxX family protein	NA	NA	NA	NA
WP_001093562.1\|801252_801693_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_000604990.1\|801972_802557_-	hypothetical protein	NA	NA	NA	NA
WP_001062972.1\|802655_803369_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000941336.1\|803372_803792_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_000446724.1\|803793_804462_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000604514.1\|804812_805406_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
WP_001217796.1\|805389_806541_+	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	6.0e-23	35.7

DBSCAN-SWA_3

818512 : 833155

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663030.1\|818512_819571_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	7.9e-22	26.7
WP_000197262.1\|819909_820452_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_025174185.1\|820894_821062_+	hypothetical protein	NA	NA	NA	NA
WP_000429006.1\|821330_822248_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	2.1e-07	22.0
WP_031760357.1\|822338_822440_+	hypothetical protein	NA	NA	NA	NA
WP_000193751.1\|822517_824023_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_000930018.1\|824365_824866_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	2.9e-51	70.8
WP_001068501.1\|824885_825752_-	DMT family transporter	NA	NA	NA	NA
WP_001790091.1\|826136_826403_+	hypothetical protein	NA	NA	NA	NA
WP_000692521.1\|826552_826951_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_000855519.1\|826913_829019_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.6
WP_000562498.1\|829136_830108_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000499195.1\|830288_830444_+	hypothetical protein	NA	NA	NA	NA
WP_000876318.1\|830482_831454_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_001245577.1\|831440_832397_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_000616840.1\|832393_833155_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	6.5e-18	31.6

DBSCAN-SWA_4

914736 : 926672

Staphylococcus_phage(85.71%)

integrase,coat,terminase

attL 914575:914593|attR 930135:930153

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
914575:914593	attL	NA	NA	NA	NA
WP_000270270.1\|914736_915957_-\|integrase	site-specific integrase	Q4ZE80	Staphylococcus_phage	1.2e-98	47.0
WP_001661453.1\|915970_917359_-	SAP domain-containing protein	NA	NA	NA	NA
WP_001661454.1\|917385_917958_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000560872.1\|918129_918351_+	helix-turn-helix transcriptional regulator	A0A2H4JFN1	uncultured_Caudovirales_phage	2.0e-07	43.5
WP_000124597.1\|918351_918624_+	helix-turn-helix domain-containing protein	Q4ZE77	Staphylococcus_phage	7.7e-38	84.4
WP_000784893.1\|918635_918782_+	hypothetical protein	NA	NA	NA	NA
WP_001058498.1\|918774_918987_+	hypothetical protein	A0A1W6JPA6	Staphylococcus_phage	1.4e-18	70.6
WP_001038250.1\|918988_919348_+	hypothetical protein	NA	NA	NA	NA
WP_001103969.1\|919348_919666_+	DUF1474 family protein	A0A1W6JQH0	Staphylococcus_phage	1.3e-33	84.1
WP_145411580.1\|919729_920599_+	mobile element-associated protein	Q4ZE74	Staphylococcus_phage	5.7e-159	93.4
WP_000447476.1\|920612_922322_+	DUF927 domain-containing protein	Q4ZE73	Staphylococcus_phage	0.0e+00	95.8
WP_000356929.1\|922651_923032_+	hypothetical protein	Q4ZE71	Staphylococcus_phage	1.0e-67	96.8
WP_001047694.1\|923028_923670_+	hypothetical protein	Q4ZE67	Staphylococcus_phage	1.0e-109	92.0
WP_001190609.1\|924016_924358_+	hypothetical protein	Q4ZE66	Staphylococcus_phage	1.1e-57	99.1
WP_000846278.1\|924369_924948_+	hypothetical protein	A0A2H4JBG0	uncultured_Caudovirales_phage	4.0e-28	37.9
WP_000404187.1\|924965_925184_+	hypothetical protein	NA	NA	NA	NA
WP_000771352.1\|925234_925762_+\|coat	spore coat protein	Q4ZE87	Staphylococcus_phage	2.7e-87	96.0
WP_072546814.1\|925866_926106_+	pathogenicity island family protein	Q4ZE86	Staphylococcus_phage	2.3e-30	81.0
WP_001293072.1\|926102_926672_+\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	1.0e-100	97.9
930135:930153	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1020222 : 1073756

Streptococcus_phage(33.33%)

bacteriocin,protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000448934.1\|1020222_1021212_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_000258003.1\|1021505_1021901_+	transcriptional regulator Spx	NA	NA	NA	NA
WP_001557163.1\|1022105_1023425_-\|transposase	ISL3-like element IS1181 family transposase	NA	NA	NA	NA
WP_001217728.1\|1023791_1024511_+	adaptor protein MecA	NA	NA	NA	NA
WP_000959282.1\|1024631_1025618_+	competence protein CoiA	NA	NA	NA	NA
WP_000082725.1\|1025665_1027474_+	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	5.5e-47	24.5
WP_000896697.1\|1027933_1028740_-	DsbA family protein	NA	NA	NA	NA
WP_000214070.1\|1028762_1029128_-	hypothetical protein	NA	NA	NA	NA
WP_000224619.1\|1029231_1029825_-	CYTH domain-containing protein	NA	NA	NA	NA
WP_001242103.1\|1030010_1030358_+	hypothetical protein	NA	NA	NA	NA
WP_001077683.1\|1030374_1031010_+	GTP pyrophosphokinase family protein	NA	NA	NA	NA
WP_001270834.1\|1031026_1031836_+	NAD kinase	NA	NA	NA	NA
WP_000669923.1\|1031832_1032687_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_000062407.1\|1032707_1034093_+	magnesium transporter	NA	NA	NA	NA
WP_000395153.1\|1034102_1035947_+	sodium:proton antiporter	NA	NA	NA	NA
WP_000933195.1\|1036224_1036995_+	enoyl-ACP reductase FabI	NA	NA	NA	NA
WP_000933105.1\|1037191_1038277_-	AI-2E family transporter	NA	NA	NA	NA
WP_000570687.1\|1038618_1040187_+	alanine:cation symporter family protein	NA	NA	NA	NA
WP_114306625.1\|1040331_1041090_+	esterase family protein	NA	NA	NA	NA
WP_000600387.1\|1041283_1041793_+	hypothetical protein	NA	NA	NA	NA
WP_001795273.1\|1041905_1043114_-	MFS transporter	NA	NA	NA	NA
WP_000258645.1\|1043073_1044249_-	diglucosyl diacylglycerol synthase	NA	NA	NA	NA
WP_000340119.1\|1044681_1046166_+	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	NA	NA	NA	NA
WP_001795833.1\|1046146_1046407_+	hypothetical protein	NA	NA	NA	NA
WP_001049950.1\|1046406_1047969_+	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	1.7e-36	28.2
WP_000928413.1\|1048270_1049074_+	TerC family protein	S5MAL1	Bacillus_phage	1.6e-30	40.5
WP_001795272.1\|1049292_1051617_+\|protease	serine protease	W5SAB9	Pithovirus	2.8e-11	27.4
WP_000021865.1\|1051633_1052992_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_000414165.1\|1053130_1054642_+	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_000287265.1\|1055128_1055698_-	competence protein ComK	NA	NA	NA	NA
WP_000876826.1\|1055907_1056126_+	IDEAL domain-containing protein	NA	NA	NA	NA
WP_000668818.1\|1056206_1057193_-	lipoate--protein ligase	NA	NA	NA	NA
WP_000214898.1\|1057391_1057568_+	YkvS family protein	NA	NA	NA	NA
WP_001033865.1\|1057582_1058185_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_031763719.1\|1059100_1059202_+	hypothetical protein	NA	NA	NA	NA
WP_001797239.1\|1059211_1059484_+\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
WP_114283588.1\|1059527_1061492_+\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA
WP_000668627.1\|1061494_1061815_+	YxeA family protein	NA	NA	NA	NA
WP_000571168.1\|1061811_1062453_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.7e-19	33.0
WP_001795266.1\|1062540_1062831_-	hypothetical protein	NA	NA	NA	NA
WP_001792054.1\|1062971_1063109_+	poly(glycerol-phosphate) alpha-glucosyltransferase	NA	NA	NA	NA
WP_000766009.1\|1063197_1063554_-	DoxX family protein	NA	NA	NA	NA
WP_001081351.1\|1064041_1065001_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001790177.1\|1065046_1065178_-	hypothetical protein	NA	NA	NA	NA
WP_001788574.1\|1065241_1065532_-	TM2 domain-containing protein	A0A060AN66	Enterococcus_phage	7.5e-07	38.0
WP_000620949.1\|1065621_1066173_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000070966.1\|1066224_1067163_-	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
WP_001791731.1\|1067313_1067418_+	hypothetical protein	NA	NA	NA	NA
WP_001816819.1\|1067494_1068706_+	isochorismate synthase	NA	NA	NA	NA
WP_000526694.1\|1068692_1070366_+	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase	NA	NA	NA	NA
WP_000150197.1\|1070352_1071156_+	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase	NA	NA	NA	NA
WP_000184945.1\|1071148_1071970_+	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
WP_000284458.1\|1072207_1072537_-	staphostatin B	NA	NA	NA	NA
WP_001089094.1\|1072574_1073756_-\|protease	cysteine protease staphopain B	NA	NA	NA	NA

DBSCAN-SWA_6

1093794 : 1102267

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000861572.1\|1093794_1094277_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7
WP_001010413.1\|1094263_1095388_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000174053.1\|1095391_1096096_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
WP_000848350.1\|1096095_1096359_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666806.1\|1096360_1097032_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_000032741.1\|1097024_1099214_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.3e-140	39.7
WP_000483720.1\|1099192_1100677_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.9e-45	31.7
WP_000030811.1\|1100669_1101698_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.4e-62	41.7
WP_000238669.1\|1101700_1102267_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.1

DBSCAN-SWA_7

1725113 : 1734156

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364542.1\|1725113_1725632_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
WP_000595011.1\|1725653_1727927_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	8.1e-64	29.3
WP_000749795.1\|1728129_1730409_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_001160682.1\|1730683_1730944_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_001112045.1\|1730962_1732102_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001019178.1\|1732124_1733150_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005768.1\|1733151_1734156_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_8

1849704 : 1921317

Staphylococcus_phage(95.65%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001266162.1\|1849704_1850349_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_000434765.1\|1850363_1851155_-	phosphotransferase family protein	NA	NA	NA	NA
WP_000411084.1\|1851704_1852553_-	D-amino-acid transaminase	NA	NA	NA	NA
WP_000265417.1\|1852556_1853966_-	Mn(2+)-dependent dipeptidase Sapep	NA	NA	NA	NA
WP_001051856.1\|1854523_1854946_-	YtxH domain-containing protein	NA	NA	NA	NA
WP_001217125.1\|1854962_1855658_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_000004334.1\|1855654_1857316_-	polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_031894898.1\|1857722_1858991_+	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	9.1e-57	99.1
WP_114306649.1\|1859107_1865668_-	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	1.7e-308	98.9
WP_000836461.1\|1865993_1866305_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	4.8e-52	99.0
WP_001108730.1\|1866326_1868741_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.5
WP_001025067.1\|1869031_1870213_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	7.3e-218	99.7
WP_000526539.1\|1870322_1871276_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_145411586.1\|1871272_1871836_+	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	4.1e-102	98.9
WP_000757543.1\|1871958_1872360_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000266096.1\|1872931_1873759_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001790712.1\|1873761_1873881_-	hypothetical protein	NA	NA	NA	NA
WP_001196362.1\|1873992_1874994_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	2.6e-184	99.4
WP_001008549.1\|1875115_1875580_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.5e-70	100.0
WP_001159037.1\|1875592_1876774_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	5.6e-226	99.5
WP_000493887.1\|1876784_1877417_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	5.5e-111	98.6
WP_000384185.1\|1877423_1878455_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	4.0e-196	98.8
WP_001261668.1\|1878947_1880450_-	FAD-dependent oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	1.9e-29	98.6
WP_000221177.1\|1880972_1881287_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	9.8e-53	98.1
WP_000989121.1\|1881286_1882579_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	5.0e-228	99.5
WP_001032833.1\|1882665_1883520_-	autolysin	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000384171.1\|1883795_1884020_-	hypothetical protein	NA	NA	NA	NA
WP_001153742.1\|1884802_1885246_+	competence protein ComK	NA	NA	NA	NA
WP_001030469.1\|1885232_1885676_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
WP_001168903.1\|1885971_1886607_+\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001096494.1\|1887046_1887760_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_000091442.1\|1888019_1888322_+	hypothetical protein	NA	NA	NA	NA
WP_001200542.1\|1888577_1888943_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
WP_000623470.1\|1888939_1889293_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	3.8e-21	94.0
WP_114306650.1\|1891289_1892123_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	3.9e-157	98.9
WP_000366163.1\|1892334_1893243_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	3.4e-138	100.0
WP_000933820.1\|1893364_1894561_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	4.3e-218	99.5
WP_000109906.1\|1894932_1896525_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
WP_012840522.1\|1896902_1897649_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	5.4e-142	98.4
WP_000672013.1\|1897653_1898127_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	7.2e-84	98.7
WP_000718107.1\|1898192_1898450_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000778527.1\|1898446_1899448_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	3.4e-184	97.0
WP_000348364.1\|1899452_1900931_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.8e-283	97.6
WP_012840523.1\|1901089_1901545_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	3.6e-80	99.3
WP_001795210.1\|1901847_1902498_+	calcium-binding protein	A0A2H4PQM8	Staphylococcus_phage	2.9e-51	94.0
WP_000070642.1\|1902578_1903574_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	2.6e-67	97.9
WP_000669024.1\|1903648_1904275_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	3.1e-74	79.8
WP_000627540.1\|1904315_1904657_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	1.1e-54	94.7
WP_000414216.1\|1904757_1905330_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	2.3e-23	93.1
WP_001801861.1\|1906684_1906780_+	type I toxin-antitoxin system Fst family toxin PepA1	NA	NA	NA	NA
WP_001792025.1\|1906902_1907004_+	hypothetical protein	NA	NA	NA	NA
WP_000072627.1\|1908079_1909309_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	4.0e-134	64.7
WP_001793440.1\|1909301_1911041_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.4e-289	100.0
WP_001791797.1\|1911021_1911156_-	hypothetical protein	NA	NA	NA	NA
WP_001038752.1\|1911218_1911938_-\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.9e-131	99.6
WP_011447030.1\|1912039_1912147_+	hypothetical protein	NA	NA	NA	NA
WP_001038704.1\|1912095_1912815_-\|protease	serine protease SplD	A0A2H4PQP9	Staphylococcus_phage	4.6e-130	99.6
WP_145411587.1\|1912935_1913655_-\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	5.1e-129	98.3
WP_001039454.1\|1913712_1914435_-\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	3.5e-130	98.3
WP_001039427.1\|1914559_1915267_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	7.9e-127	97.0
WP_001792819.1\|1915702_1915921_-	hypothetical protein	NA	NA	NA	NA
WP_001092780.1\|1916229_1916811_+	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	9.6e-54	64.8
WP_000469591.1\|1917283_1917502_-	hypothetical protein	A0A2H4PQH0	Staphylococcus_phage	2.0e-25	80.6
WP_000550252.1\|1917757_1918231_+	hypothetical protein	NA	NA	NA	NA
WP_000543854.1\|1918235_1919027_+	DUF1828 domain-containing protein	NA	NA	NA	NA
WP_000782463.1\|1919396_1920380_-	bi-component leukocidin LukED subunit D	A0A2H4PQH7	Staphylococcus_phage	1.8e-185	99.4
WP_114306651.1\|1920381_1921317_-	beta-channel forming cytolysin	A0A2H4PQI5	Staphylococcus_phage	6.7e-174	99.7

DBSCAN-SWA_9

2025622 : 2125451

107

Staphylococcus_phage(74.24%)

plate,integrase,portal,protease,tRNA,tail,terminase,capsid,holin,head

attL 2025014:2025038|attR 2127737:2127761

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2025014:2025038	attL	NA	NA	NA	NA
WP_000545370.1\|2025622_2027050_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_000027917.1\|2027062_2028520_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_000170162.1\|2028521_2028824_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_000957020.1\|2029190_2030729_+	sodium/proline symporter PutP	NA	NA	NA	NA
WP_000831700.1\|2030817_2032017_-	CamS family sex pheromone protein	NA	NA	NA	NA
WP_000774556.1\|2032029_2034033_-	NAD-dependent DNA ligase LigA	A0A0K2QQN8	Ralstonia_phage	1.2e-114	36.2
WP_000992924.1\|2034036_2036229_-	DNA helicase PcrA	A7KV33	Bacillus_phage	1.0e-135	42.2
WP_000272056.1\|2036225_2036918_-	heptaprenylglyceryl phosphate synthase	NA	NA	NA	NA
WP_001165363.1\|2037089_2037392_-	hypothetical protein	NA	NA	NA	NA
WP_000572878.1\|2037500_2038796_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.6e-16	32.9
WP_000434933.1\|2040854_2041181_+	staphostatin A	NA	NA	NA	NA
WP_000669862.1\|2041472_2041646_-	NETI motif-containing protein	NA	NA	NA	NA
WP_000011542.1\|2041626_2042229_-	DUF2179 domain-containing protein	NA	NA	NA	NA
WP_000040866.1\|2042499_2043321_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	2.3e-69	52.7
WP_000284436.1\|2043313_2044783_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	5.9e-108	45.1
WP_000897635.1\|2044966_2046043_+	nitric oxide synthase oxygenase	NA	NA	NA	NA
WP_001177828.1\|2046062_2046857_+	prephenate dehydratase	NA	NA	NA	NA
WP_001802312.1\|2046928_2047036_+	hypothetical protein	NA	NA	NA	NA
WP_000323161.1\|2047046_2048609_-	SLC13 family permease	NA	NA	NA	NA
WP_000275727.1\|2048813_2049911_-	pectate lyase	U5PWM6	Bacillus_phage	3.3e-47	34.6
WP_000149686.1\|2050279_2050840_+	cysteine hydrolase	G3MA16	Bacillus_virus	2.0e-32	41.2
WP_001140871.1\|2050892_2051822_+	manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
WP_001792184.1\|2052014_2052188_-	hypothetical protein	NA	NA	NA	NA
WP_001021210.1\|2052239_2053619_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_000181315.1\|2053738_2054767_-	lactonase family protein	NA	NA	NA	NA
WP_000205106.1\|2055036_2055438_+	YolD-like family protein	U3PG23	Staphylococcus_phage	6.0e-23	42.9
WP_000267034.1\|2056010_2056184_-	hypothetical protein	NA	NA	NA	NA
WP_001188043.1\|2056634_2057675_+	linear amide C-N hydrolase	NA	NA	NA	NA
WP_000713072.1\|2057731_2058574_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_001033971.1\|2058570_2059128_-	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_000966288.1\|2059187_2059712_-	membrane protein	NA	NA	NA	NA
WP_000182842.1\|2059832_2060396_+	thioredoxin family protein	NA	NA	NA	NA
WP_001221651.1\|2060461_2061202_-	phenol-soluble modulin export ABC transporter permease subunit PmtD	NA	NA	NA	NA
WP_000763043.1\|2061201_2062074_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtC	A0A2H4PQG7	Staphylococcus_phage	1.0e-27	36.0
WP_000645727.1\|2062070_2062751_-	phenol-soluble modulin export ABC transporter permease subunit PmtB	NA	NA	NA	NA
WP_000991306.1\|2062751_2063648_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtA	A0A2H4PQG7	Staphylococcus_phage	5.0e-17	30.2
WP_000691584.1\|2063644_2064025_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000681968.1\|2064282_2064459_-	hypothetical protein	NA	NA	NA	NA
WP_000990056.1\|2064701_2064800_-	hypothetical protein	NA	NA	NA	NA
WP_001068542.1\|2064999_2066286_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_001797815.1\|2066564_2066885_-	MAP domain-containing protein	NA	NA	NA	NA
WP_114306654.1\|2066869_2068300_-	MAP domain-containing protein	NA	NA	NA	NA
WP_000766912.1\|2069548_2070502_-	ornithine cyclodeaminase family protein	NA	NA	NA	NA
WP_000185611.1\|2071178_2071919_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000930251.1\|2072263_2073718_-	CHAP domain-containing protein	A0A0N6WMR3	Staphylococcus_phage	2.3e-277	95.6
WP_000387655.1\|2073728_2074031_-\|holin	phage holin	A0A2I6PET6	Staphylococcus_phage	6.5e-46	94.0
WP_000466781.1\|2074569_2074869_-	DUF2951 family protein	A0A2I6PER2	Staphylococcus_phage	4.5e-31	99.0
WP_000916020.1\|2074914_2075079_-	XkdX family protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
WP_001166602.1\|2075071_2075461_-	DUF2977 domain-containing protein	M9QYR4	Staphylococcus_phage	2.8e-57	92.2
WP_000067150.1\|2075460_2076927_-\|plate	BppU family phage baseplate upper protein	Q4ZCZ8	Staphylococcus_virus	9.3e-255	93.0
WP_000429548.1\|2076926_2078837_-	hypothetical protein	R4WAL5	Staphylococcus_phage	0.0e+00	99.4
WP_000179860.1\|2078852_2079143_-	hypothetical protein	A0A2I6PF46	Staphylococcus_phage	2.1e-49	100.0
WP_000384455.1\|2079142_2080726_-	peptidase	M9QX27	Staphylococcus_phage	3.5e-308	99.4
WP_001190533.1\|2080734_2081559_-\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	4.1e-159	100.0
WP_001003411.1\|2081558_2087735_-\|tail	phage tail tape measure protein	A0A2I6PEL0	Staphylococcus_phage	0.0e+00	96.9
WP_012840525.1\|2087748_2087907_-	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.9e-17	86.5
WP_000589169.1\|2087948_2088299_-	hypothetical protein	A0A2I6PEQ2	Staphylococcus_phage	6.8e-55	98.3
WP_000169126.1\|2088356_2088812_-	Ig domain-containing protein	Q9B0D4	Staphylococcus_phage	1.2e-75	96.7
WP_000807543.1\|2088903_2089545_-\|tail	tail protein	A0A2I6PE59	Staphylococcus_phage	4.7e-118	97.2
WP_001023810.1\|2089579_2089975_-	DUF3168 domain-containing protein	A0A0K1LKC0	Staphylococcus_phage	7.4e-66	98.5
WP_000110016.1\|2089975_2090377_-	hypothetical protein	A0A0K1LL98	Staphylococcus_phage	1.2e-66	98.5
WP_000395500.1\|2090373_2090706_-	hypothetical protein	A0A2I6PES3	Staphylococcus_phage	7.6e-56	98.2
WP_000050973.1\|2090717_2090996_-\|head,tail	phage gp6-like head-tail connector protein	A0A2I6PEQ1	Staphylococcus_phage	2.1e-46	100.0
WP_012840526.1\|2091064_2092228_-\|capsid	phage major capsid protein	A0A2I6PDD7	Staphylococcus_phage	5.2e-216	99.0
WP_000061859.1\|2092239_2093013_-\|protease	Clp protease ClpP	A0A2I6PEQ7	Staphylococcus_phage	1.2e-136	99.6
WP_001100667.1\|2092996_2094235_-\|portal	phage portal protein	A0A2K9VBP0	Staphylococcus_phage	1.5e-234	99.8
WP_114306655.1\|2094239_2095931_-\|terminase	terminase large subunit	A0A2I6PDP8	Staphylococcus_phage	0.0e+00	97.3
WP_000778931.1\|2095920_2096226_-\|terminase	P27 family phage terminase small subunit	A0A2I6PEQ6	Staphylococcus_phage	1.4e-48	99.0
WP_000160696.1\|2096352_2096667_-	HNH endonuclease	M9QQL5	Staphylococcus_phage	5.5e-56	99.0
WP_000590121.1\|2096821_2097238_-	hypothetical protein	A0A1X9H0U8	Staphylococcus_phage	1.1e-75	99.3
WP_000264723.1\|2097265_2097466_-	DUF1514 family protein	R9QT57	Staphylococcus_phage	3.2e-25	89.4
WP_000141181.1\|2097465_2097708_-	hypothetical protein	NA	NA	NA	NA
WP_000195822.1\|2097704_2097911_-	DUF1381 domain-containing protein	A0A0H4IPW6	Staphylococcus_phage	8.4e-29	95.6
WP_000185696.1\|2097947_2098484_-	hypothetical protein	M1SNY5	Staphylococcus_phage	1.4e-94	98.3
WP_000066807.1\|2098476_2098719_-	hypothetical protein	Q8SDV4	Staphylococcus_phage	6.0e-34	98.8
WP_001065082.1\|2098708_2098960_-	DUF1024 family protein	A1KX83	Staphylococcus_virus	1.2e-37	98.8
WP_001126847.1\|2098974_2099223_-	hypothetical protein	A0A2I6PDI0	Staphylococcus_phage	1.6e-37	91.5
WP_000029396.1\|2099223_2099583_-	hypothetical protein	Q8SDV7	Staphylococcus_phage	2.7e-59	95.8
WP_001187247.1\|2099583_2099769_-	DUF3113 family protein	B7T0B3	Staphylococcus_virus	1.1e-24	93.4
WP_078056504.1\|2100237_2100651_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000123130.1\|2100629_2100830_-	hypothetical protein	NA	NA	NA	NA
WP_012840529.1\|2100826_2102683_-	primase	B6D7K5	Listeria_phage	3.6e-118	40.8
WP_000184025.1\|2104457_2105093_-	hypothetical protein	NA	NA	NA	NA
WP_001003951.1\|2105115_2105874_-	DUF1351 domain-containing protein	A0A2H4J082	uncultured_Caudovirales_phage	1.4e-07	23.1
WP_000171560.1\|2105884_2106208_-	hypothetical protein	A0A2I6PDL5	Staphylococcus_phage	5.7e-24	54.2
WP_001105358.1\|2106220_2106832_-	hypothetical protein	B6D7K1	Listeria_phage	4.1e-47	45.6
WP_000802314.1\|2106854_2107091_-	hypothetical protein	D2JGJ9	Staphylococcus_phage	5.5e-32	83.1
WP_000291082.1\|2107098_2107359_-	DUF1108 family protein	Q4ZDY8	Staphylococcus_virus	2.7e-16	47.7
WP_001285953.1\|2107457_2107619_-	DUF1270 family protein	A7TWM3	Staphylococcus_phage	5.6e-20	96.2
WP_001120202.1\|2107615_2107936_-	DUF771 domain-containing protein	A0A2I6PDH6	Staphylococcus_phage	5.6e-56	98.1
WP_078099424.1\|2107905_2108097_+	hypothetical protein	W5R9J5	Staphylococcus_phage	3.3e-11	92.1
WP_000939498.1\|2108086_2108230_-	hypothetical protein	W5R8I6	Staphylococcus_phage	2.5e-16	100.0
WP_031838117.1\|2108505_2108703_-	hypothetical protein	A7TWF5	Staphylococcus_phage	9.5e-22	93.8
WP_000362645.1\|2108771_2108984_+	hypothetical protein	D2JGJ1	Staphylococcus_phage	1.3e-32	98.6
WP_000435352.1\|2109188_2109632_-	hypothetical protein	A7TWF2	Staphylococcus_phage	1.1e-73	97.3
WP_000272856.1\|2109644_2109893_-	helix-turn-helix transcriptional regulator	Q4ZBN5	Staphylococcus_phage	1.8e-38	98.8
WP_001260487.1\|2110056_2110380_+	helix-turn-helix transcriptional regulator	A0A0H3U2V8	Staphylococcus_phage	2.0e-53	100.0
WP_000525014.1\|2110392_2110854_+	hypothetical protein	R4WEA5	Staphylococcus_phage	1.6e-83	99.3
WP_001025527.1\|2111385_2112270_+	hypothetical protein	A0A0K1LKD8	Staphylococcus_phage	3.4e-151	91.8
WP_000857172.1\|2114415_2115453_+\|integrase	site-specific integrase	Q4ZCY6	Staphylococcus_virus	3.1e-172	96.5
WP_000595392.1\|2116571_2117588_-	bi-component leukocidin LukGH subunit G	A0A1X9IGW5	Staphylococcus_phage	6.7e-26	30.2
WP_145373886.1\|2117609_2118665_-	bi-component leukocidin LukGH subunit H	A0A1X9IGW5	Staphylococcus_phage	2.1e-35	34.3
WP_000206625.1\|2119100_2120324_+	ArgE/DapE family deacylase	NA	NA	NA	NA
WP_001045079.1\|2120709_2122017_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_000240647.1\|2122556_2124173_-	chaperonin GroEL	A0A240F779	uncultured_virus	1.3e-156	54.5
WP_000917289.1\|2124248_2124533_-	co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2
WP_000197635.1\|2124707_2125451_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
2127737:2127761	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP042153

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

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Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection