CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP042164	Burkholderia contaminans strain ZCC chromosome 1, complete sequence	2 crisprs	cas3,DEDDh,csa3,Cas14u_CAS-V,DinG,WYL	0	4
NZ_CP042165	Burkholderia contaminans strain ZCC chromosome 2, complete sequence	2 crisprs	csa3,DinG,cas3,Cas14u_CAS-V,c2c9_V-U4,WYL	1	0
NZ_CP042168	Burkholderia contaminans strain ZCC plasmid unnamed2, complete sequence	0 crisprs	NA	0	0
NZ_CP042166	Burkholderia contaminans strain ZCC chromosome 3, complete sequence	0 crisprs	WYL,RT	0	118
NZ_CP042167	Burkholderia contaminans strain ZCC plasmid unnamed1, complete sequence	0 crisprs	csa3	0	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP042164_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042164_1

932298-932390

Orphan

Consensus_repeat	Method
CACTCGGCAACCTCGGCGGCTCGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP042164_1

>merge|NZ_CP042164|1|932298-932390|CRISPRCasFinder
CACTCGGCAACCTCGGCGGCTCGAGTCCGCTGGCCCCGGTACAGGGCGTCGTGAACCAGGTGGTCGGCACGCTCGGCAACCTCGGCGGCTCGA

>NZ_CP042164|1|1|932298-932390|CRISPRCasFinder
CACTCGGCAACCTCGGCGGCTCGA	GTCCGCTGGCCCCGGTACAGGGCGTCGTGAACCAGGTGGTCGGCA
CGCTCGGCAACCTCGGCGGCTCGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042164.1\|WP_039361190.1\|927181_927961_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270421
NZ_CP042164.1\|WP_039361175.1\|935997_936513_+\|polyketide-cyclase	unknown	unknown	gnl\|CDD\|176866
NZ_CP042164.1\|WP_039361169.1\|937637_939236_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224099
NZ_CP042164.1\|WP_039361204.1\|914327_915770_-\|C4-dicarboxylate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270238
NZ_CP042164.1\|WP_039361178.1\|935320_935953_+\|DUF1571-domain-containing-protein	unknown	unknown	gnl\|CDD\|377879
NZ_CP042164.1\|WP_039361173.1\|936559_937609_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226361
NZ_CP042164.1\|WP_039361167.1\|939238_940273_-\|iron-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270261
NZ_CP042164.1\|WP_039361188.1\|928027_929272_+\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223737
NZ_CP042164.1\|WP_039361183.1\|933175_933535_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226765
NZ_CP042164.1\|WP_039361202.1\|916208_916574_+\|BON-domain-containing-protein	unknown	unknown	gnl\|CDD\|335963
NZ_CP042164.1\|WP_039361197.1\|922535_923975_-\|DHA2-family-efflux-MFS-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|129794
NZ_CP042164.1\|WP_039361199.1\|921404_922193_-\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NZ_CP042164.1\|WP_039361200.1\|919411_921247_+\|peptidase-S1	unknown	unknown	gnl\|CDD\|225490
NZ_CP042164.1\|WP_011694181.1\|925039_925687_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225512
NZ_CP042164.1\|WP_039361181.1\|934081_934864_+\|anti-sigma-factor	unknown	unknown	gnl\|CDD\|227949
NZ_CP042164.1\|WP_039361192.1\|925827_926802_-\|ornithine-cyclodeaminase-family-protein	unknown	unknown	gnl\|CDD\|225280
NZ_CP042164.1\|WP_039361164.1\|940338_941643_-\|deferrochelatase/peroxidase-EfeB	unknown	unknown	gnl\|CDD\|273606
NZ_CP042164.1\|WP_039361534.1\|933569_934085_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|237123
NZ_CP042164.1\|WP_039361532.1\|934904_935324_+\|quinol-oxidase	unknown	unknown	gnl\|CDD\|259885
NZ_CP042164.1\|WP_039361196.1\|924112_924844_-\|DsbA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|239322

Protein	Function_ID	Function_description	E-value
NZ_CP042164.1\|WP_039361190.1\|927181_927961_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270421	cd13703, PBP2_HisJ_LAO, Substrate binding domain of ABC-type histidine- and lysine/arginine/ornithine transporters; the type 2 periplasmic-binding protein fold. This subgroup includes the periplasmic-binding proteins, HisJ and LAO, that serve as initial receptors in the ABC transport of histidine and lysine-arginine-ornithine amino acids. They are belong to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	5.04826e-115
NZ_CP042164.1\|WP_039361175.1\|935997_936513_+\|polyketide-cyclase	gnl\|CDD\|176866	cd07824, SRPBCC_6, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	8.6335e-67
NZ_CP042164.1\|WP_039361169.1\|937637_939236_-\|iron-ABC-transporter-permease	gnl\|CDD\|224099	COG1178, ThiP, ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism].	1.99901e-89
NZ_CP042164.1\|WP_039361204.1\|914327_915770_-\|C4-dicarboxylate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270238	cd13520, PBP2_TAXI_TRAP, Substrate binding domain of TAXI proteins of the tripartite ATP-independent periplasmic transporters; the type 2 periplasmic binding protein fold. This group includes Thermus thermophilus GluBP (TtGluBP) of TAXI-TRAP family and closely related proteins. TRAP transporters are ubiquitous in prokaryotes, but absent from eukaryotes. They are comprised of an SBP (substrate-binding protein) of the DctP or TAXI families and two unequally sized integral membrane components. Although TtGluBP is predicted to be an L-glutamate and/or an L-glutamine-binding protein, the substrate spectrum of TAXI proteins remains to be defined. A sequence-homology search also shows that TtGluBP shares low sequence homology with putative immunogenic proteins of uncharacterized function. The substrate-binding domain of TAXI proteins belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and tworeceptor cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.26697e-28
NZ_CP042164.1\|WP_039361178.1\|935320_935953_+\|DUF1571-domain-containing-protein	gnl\|CDD\|377879	pfam07608, DUF1571, Protein of unknown function (DUF1571). A family of paralogous proteins in Rhodopirellula baltica.	4.79102e-06
NZ_CP042164.1\|WP_039361173.1\|936559_937609_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	6.85311e-118
NZ_CP042164.1\|WP_039361167.1\|939238_940273_-\|iron-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270261	cd13543, PBP2_Fbp, Substrate binding domain of ferric iron transporter, a member of the type 2 periplasmic binding fold superfamily. The periplasmic iron binding protein plays an essential role in the iron uptake pathway of Gram-negative pathogenic bacteria from the Pasteurellaceae and Neisseriaceae families and is critical for survival of these pathogens within the host. This periplasmic protein (Fbp) has high affinities for ferric iron and serves as the primary receptor for transport. After binding iron with high affinity, Fbp interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The ferric iron-binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	7.70525e-141
NZ_CP042164.1\|WP_039361188.1\|928027_929272_+\|FAD-binding-oxidoreductase	gnl\|CDD\|223737	COG0665, DadA, Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism].	1.23835e-48
NZ_CP042164.1\|WP_039361183.1\|933175_933535_+\|hypothetical-protein	gnl\|CDD\|226765	COG4315, COG4315, Uncharacterized protein conserved in bacteria [Function unknown].	1.13168e-39
NZ_CP042164.1\|WP_039361202.1\|916208_916574_+\|BON-domain-containing-protein	gnl\|CDD\|335963	pfam04972, BON, BON domain. This domain is found in a family of osmotic shock protection proteins. It is also found in some Secretins and a group of potential haemolysins. Its likely function is attachment to phospholipid membranes.	2.94434e-10
NZ_CP042164.1\|WP_039361197.1\|922535_923975_-\|DHA2-family-efflux-MFS-transporter-permease-subunit	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	2.39396e-64
NZ_CP042164.1\|WP_039361199.1\|921404_922193_-\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	1.12201e-24
NZ_CP042164.1\|WP_039361200.1\|919411_921247_+\|peptidase-S1	gnl\|CDD\|225490	COG2939, COG2939, Carboxypeptidase C (cathepsin A) [Amino acid transport and metabolism].	1.01338e-125
NZ_CP042164.1\|WP_011694181.1\|925039_925687_-\|hypothetical-protein	gnl\|CDD\|225512	COG2964, COG2964, Uncharacterized protein conserved in bacteria [Function unknown].	1.2966e-69
NZ_CP042164.1\|WP_039361181.1\|934081_934864_+\|anti-sigma-factor	gnl\|CDD\|227949	COG5662, COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription].	5.72566e-25
NZ_CP042164.1\|WP_039361192.1\|925827_926802_-\|ornithine-cyclodeaminase-family-protein	gnl\|CDD\|225280	COG2423, COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog [Amino acid transport and metabolism].	2.00881e-64
NZ_CP042164.1\|WP_039361164.1\|940338_941643_-\|deferrochelatase/peroxidase-EfeB	gnl\|CDD\|273606	TIGR01412, Probable_deferrochelatase/peroxidase_EfeN, Tat-translocated enzyme. This model represents a small family of proteins with a typical Tat (twin-arginine translocation) signal sequence, suggesting that the family is exported in a folded state, perhaps with a bound redox cofactor. Members of this family show homology to Dyp, a dye-decolorizing peroxidase from Geotrichum candidum that lacks any typical heme-binding site.	2.67034e-148
NZ_CP042164.1\|WP_039361534.1\|933569_934085_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|237123	PRK12511, PRK12511, RNA polymerase sigma factor; Provisional.	9.33278e-41
NZ_CP042164.1\|WP_039361532.1\|934904_935324_+\|quinol-oxidase	gnl\|CDD\|259885	cd04223, N2OR_C, The C-terminal cupredoxin domain of Nitrous-oxide reductase. Nitrous-oxide reductase participates in nitrogen metabolism and catalyzes the last step in dissimilatory nitrate reduction, the two-electron reduction of N2O to N2. It contains copper ions as cofactors in the form of a binuclear CuA center at the site of electron entry and a tetranuclear CuZ centre at the active site. The C-terminus of Nitrous-oxide reductase is a cupredoxin domain.	2.35564e-06
NZ_CP042164.1\|WP_039361196.1\|924112_924844_-\|DsbA-family-oxidoreductase	gnl\|CDD\|239322	cd03024, DsbA_FrnE, DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins.	3.20183e-82

>NZ_CP042164.1|WP_039361188.1|928027_929272_+|FAD-binding-oxidoreductase
MDFDVIVLGAGIVGVSSALHLQDRGLRVALVDRRAPGEETSHGNAGLIERSSVVPYAFPRRLGTLLRYARNRSVDLYWDYRALPAYAGWLARFWRESSPQRLAAAARDLLPLVAASVAEHDALLARTDAQPLVHDGGWIEAFRSPALFDAETRAQQRVADAHGLRMTVLDAGALRAREPGIGDAFCGAFHWQDPKTVSSPGGLTKAYARLFERAGGTFALGDARTLVQVDDGWQVGTEHGPISARSAVVALGPWSDHVFEPLGYRIPLRAKRGYHMHYRPTRAPLNVPVCDTEAGFVVAPMEGGRLRLTTGVEIALRGAPPTGVQLARAEPLARDAFGIGERLDPEPWLGMRPCTPDMRPVIGPAPRHRHLWFAFGHCHHGLTLGPATGRLLAEMMTGAPTYIDPHPYRPARFG
>NZ_CP042164.1|WP_039361190.1|927181_927961_+|ABC-transporter-substrate-binding-protein
MNWKLSLCAAAALACAAVTAHAEQTTLRFGIEAAYPPFESKTPAGQLQGFDVDIGNAVCAKLNMKCVWVENAFDGLIPALQARKFDAINSAMNITSKRRQSIDFTPAIYVVPIVMIARHGSSLRPDVASLRGKHVGVLQGSSQEDFLKAHWATAGVAVVSYQDQDQIYADLVAGRLDAAVQEAQTAQDGFLDKPAGRDYQIVGEPLKDPATLGEGTGFGMRKSDKALQAKIVGALDALKKDGTLSALSQKYFKRDIVAK
>NZ_CP042164.1|WP_039361192.1|925827_926802_-|ornithine-cyclodeaminase-family-protein
MTQTAPTLPLTVDEAAVRAALPSLDVLGTLRSMFASLAAARAVQPPQTLTLFPDQAGDFITYLGALADAQVFGAKLSPYVVTGGKPDGKPIVTAWTALMSMRTGQPLMWCDAGLLTVERTAGTTALAVDCLAPRDARHLAIVGAGAVGLAHLRHTAGLRDWETIRVYAPSLAGDAAQQAALAQLDPRARAAASVEACVRDADVVMLCTSSGTPVLGDGMLTRPALVTSISTNVARAHEIPPAWLPDMDVYCDYRHTTPASAGEMQIAAAEHGWDAARIAGDLPALVAGTCPAPSYARHAFFRSIGLGLEDIAIAHALYTHLARA
>NZ_CP042164.1|WP_011694181.1|925039_925687_-|hypothetical-protein
MRKKKSPVKDLLLTRYAPIADGIAALFFPYAEVVIHDLHDQTVLYLANNLSKREVGDDSALEEIDHSARERVIGPYEKLNWDGRRMRCVSNVLFDDEGRPAGMMCINFNIAVFDEVRATLDLFIKGAGVVAQPDELFRDDWQERINTFLHGWLRERQVGLNGLTREHRRELVEALYAEGAFRGKSAANYVANVLGMGRATVYKHLKHLKETQGDA
>NZ_CP042164.1|WP_039361196.1|924112_924844_-|DsbA-family-oxidoreductase
MTTAPAPTARPTLTVEIWSDLICPWCWIGKRRFDEALATFAHADRVDVALRAYRLMPGQPVEPVEAMLGGKYRMSPAQVDQMLRQVTDAAASVGLRYDLPGTLVGDTLDGHRLVKLAEATGRAHALTERLYRAYFCEHGSLFDHAELTEFAVEAGLERSAVEAVLRSDQYRAEVEADVARAAQIGGRGVPLFVFGGRYAVSGAQPADAFAQALDQAWRDGIVELDGGDAAACGPDGCELPARS
>NZ_CP042164.1|WP_039361197.1|922535_923975_-|DHA2-family-efflux-MFS-transporter-permease-subunit
MTHGIHGEKRWYALIVLCLGVLMIVLDSTIVNVALPSISTDLHFTETALVWVVNAYLLTFGGCLLLGGRLGDLYGQRRMFLAGLVVFTLASLACGLAQSQAMLIAARAVQGIGGAVVSAVALSLIMNLFTEPGERARAMGVYGFVCAGGGSIGVLLGGLLTSSLSWHWIFLVNLPIGIAVYAMCVSLLPRLRAPAGTARLDVAGAITVTASLMLAVYGIVGGNEAGWLSTQTVALIGAAVALLAMFIAIEARAAHPLMPLSLFSSRNVALANVIAVLWAAAMFAWFFLSALYMQRVLGYGPLQVGLAFLPANLIMAAFSLGLSARIVMRFGIRGPIAAGLLIAACGLALFSRAPVDGGFVWHVLPGMTLLGIGAGVAFNPVLLAAMSDVDPSDSGLASGIVNTAFMMGGALGLAVLASLAAARSNTLAAANAAPLDALNGGYHAAFAFGAAFAAVAALIGFALRIRQQGAVEGVGPAMH
>NZ_CP042164.1|WP_039361199.1|921404_922193_-|sulfite-exporter-TauE/SafE-family-protein
MSLPHIDLLYSLSGLFVGILVGLTGVGGGSLMTPILVLLFGVHPATAVGTDLLYAAATKATGTLVHGLKGSIDWRITGRLAAGSVPAAAITLWWLHTHGMNAPGTARMIQLVLGVALLLTSLALIFRPQLTAFAARNPLAPSPTRTLWSTVLTGAVLGVLVSMTSVGAGAIGVTVLLLLYPALATTRIVGSDIAHAVPLTLVAGMGHWLLGSVDWSMLLSLLLGSLPGIVLGSLLSARAPERLLRNLLASTLVAVGIRLVLA
>NZ_CP042164.1|WP_039361200.1|919411_921247_+|peptidase-S1
MTTRKSLKDGFALFGTTLSVPLAAAAAAALLVTGCGGDDGASPAASAAAAAATSAGASTSANTNATAAAADQPYVDNDVYGTGPNDAVTDSTEGAAVVHRTVTIGGKAIKYTATTGHLTTIDPVTSAPNAKMFYVAYTQDNPDPSKPRPVTFFYNGGPGSSSVYLLLGSYGPKRLQSSFPNFTPPAPYKLLDNPDSLLDRTDLVFINPVGTGYSAAIAPAKNKDFWGTDQDARSIDRFIQRYLTKYSRWNSPKFLYGESYGTARSAVVSWVLHEDGIDLNGITLQSSILDYANALSAPGTFPTLAADAFYWKKTTLNPTPTDLDAYMVQARNYADNTLAPLAQKPNPQDGGFVNVRLNLNLQTAQQMGAYIGTDPTSLIQTFGNPAALGNVPSSNDNPPYTFFLTLVPGTQIGQYDGRANFTGKGIAPYILPNSGSNDPSITNVGGAYTVLWNSYINTDLKYTSTSSFVDLNDQVFNNWDFSHTDPTGANKGGGNTLYTAGDLASTMSVNPDLKVLSANGYFDAVTPFHQTELTLAQMPLDPTLKAQNLTIKNYPSGHMIYLNDASRTALKGDLANFYDGILANRTALQRVLKLQMRTQQLKQQKLQQQGQ
>NZ_CP042164.1|WP_039361202.1|916208_916574_+|BON-domain-containing-protein
MKSIVLRALGVAAVAACLSGSVYAQSSDAAATEAPAAATSAPKAAAKTAKKANRKLGYAVRKAITKAGGIDVANIVVRSKGGAITLEGTVPDQAQIDKAEEAAKGVQGVTSVSNKLTVQQQ
>NZ_CP042164.1|WP_039361204.1|914327_915770_-|C4-dicarboxylate-ABC-transporter-substrate-binding-protein
MKPARPRPPRRILARFVAVSWRDLALSIGPTVLLAGAAVWLAVKLIQPAPPSTLVISSGPPGSTYWNAAQKYKTILAKNGVTLDVQSSEGSAQNLARLSNPNAPVDVGFVQSGIGPKERDEHLVSLGSIGYVPLAIMYRGPVVARLSDFKGKRLALGAEGSGARELSLALLKMNGIVPGGSTELLPTAGEDAATALLDGKIDAAFLSGDSTQIPVMAKLFRAPGVHVYSFTQAEAYARRFPYLTAITLPMGVYDLGRNLPPADIHTVAPTIELVARDSLHPALSDLLIEAAREVHGHATILQHAGEFPSSVTRGFPLSDDAARYYKSGKTFLYRRLPFWVASLVDRLLVVVVPLIVVLIPGLRLVPSLYGWRVRSRIYRWYGALIALERSALGEHTAEERVKLLDELDDIEEAVNRMKMPLAYAGQFYVLREHIGFVRERLTAHDQDTPAGPPGAGGPPHARAEAAPPAGTPPRATPGSA
>NZ_CP042164.1|WP_039361183.1|933175_933535_+|hypothetical-protein
MNRILVVAALTAAVVRPAAAEPPRAGDGKLVDEDHMTLYVFDRDAPGKSACDRACATNWPPALADAYDKATGALSVVARDDGSKQWAYRGRPLYRWKLDHKPGDAGGDGVGGMWHVARP
>NZ_CP042164.1|WP_039361534.1|933569_934085_+|sigma-70-family-RNA-polymerase-sigma-factor
MSYESDLLVWLPHLTRYARALTGDRAWADDLVQDTLERALNRPPRDGGNLRAWLLTLLRHRFIDQLRARHEIAVDDATAPWQTMAAPAGEIGGLVLRDVQRALYRLPVEQREVLLLVALEELSYRDAAEVLGVPVGTVMSRLARARGQMRALLSDEPPAHGTAALRVIGKT
>NZ_CP042164.1|WP_039361181.1|934081_934864_+|anti-sigma-factor
MMDDPHKPSNARDDDASAQLLSALLDGELSGHERREVLERVLADPEEAERLAHYRAQRDALQALFPLPAAAPALFVQRREPRRRGIAYAFAGLAAGLLIGVALHAGWVAFGGEPGFAARADVAYATYVADRDHPVEVSAGDPDHLVAWLSARLGRPVRAPSLDEYGYRLLGGRLLPGEAGPAAQLMYQRADGERVTLYMTAYDTRRLAPQAMSAGGRYTYFWSDRGMGYALSGQGDERRLRELAIDACGALGGPTDAWKG
>NZ_CP042164.1|WP_039361532.1|934904_935324_+|quinol-oxidase
MTKGLVPMLVLAALAAGTALAQADGDVPLRVPVDADGVQRVAIVGGSYFFRPNHVIVRAHVPVELTVSAEPGPVPHSFEIDAPQAGIAVRTELGTTPKTFRFTPSQPGRFAYYCTHRLLFFKSHRERGMEGALDVEAAP
>NZ_CP042164.1|WP_039361178.1|935320_935953_+|DUF1571-domain-containing-protein
MIAALLAASLIGASMTADPVTVAQAHFDHVRSYRATIRSSARGGEHTEIRYAYLKPGFVRMDFVSPHHGAVLAYDPGDGKVRLRPFGAHAPPALTLSPSNPLVRDRSGHRVDRSDVGELLRNVHALQEGGATVTEGEEAVGGRTALRVSVTGAPAHAVDGVHRYRLWLDTEDGFPLKVVSFADGDDVPLETVTLDDVEIDVAFPERFFAP
>NZ_CP042164.1|WP_039361175.1|935997_936513_+|polyketide-cyclase
MAEYRFSTIWRVDAPLVAVWDAIYQVDRWPVWWKGAVRTVEIEPGDVRGVGALHRYTWKGALPYRLTFDMRVRRVEPPHALEGRAGGAIEGDGCWSFIADGARTIVRYDWHIRTHVRWMNRLEWLGRPLFRWNHDVVMREGAKGLARLLGAAVETEGRTFRPLPDAGCADA
>NZ_CP042164.1|WP_039361173.1|936559_937609_-|ABC-transporter-ATP-binding-protein
MSELRIHGLSKSFGSHTVLHDIDLTVRRGSRLALLGPSGSGKTTLLRVLCGFERAERGTVEIDGRRVAAPDVHLPPEQRRIGYVPQEGALFPHLSVADNIAFGLPRAARRRHHRVDELLEMVGLPASYASRAPQQLSGGQQQRVALARALAPEPSLVILDEPFSALDTSLRHETRSAVADALAAAGATSVLVTHDQPEAMTLGDEVAVMWHGRLVQTAAPQTLYRQPITRDVASFVGQAVLLAGRVRGTHIACALGDLPLVAPLPDGPADAMLRPEQIGIVPLTHADAARGHTARVEAAQFAGQDADVLLRLDADGDVRVRARVPGHRCPAVGERVALVVDGAVMAYAC
>NZ_CP042164.1|WP_039361169.1|937637_939236_-|iron-ABC-transporter-permease
MSDAVSRTARAARGGEHMATRRRPSRALVAAAACGPLAILLPLGFTLYRAATFGIDDAIELLWRPLVGELLVNTLSITLAATLACTLLGTALAWFIERTDLPARPLWTALAAAPLAVPPFITSYAWVSLSLDLQDFLGALIVLTSAYFPLVYLPVAAALRELDPALEESARTLGCSPWHTFFRVVLPQLRPALCGGMLLVALGVLSEFGAFQLLRFRTFTTEIYAEYRTAFDGGGASLLGCVLIALCLLCLAIEARARGHARYGHTHRAARRVAMRYPLGRLRGPVTVAFAALAAATLGVPLAMIGYWLTQQGAAAVTPADVSPELLWQATLASSGYGLMAAAVTTLLALPLAFLLVRYPGRVATLLERTAMTVQGVPGIVVALAIVSITVRLLQPLYQSAPALVGAYAILFLPLAVVSVRAALSHVQVRLEETARSLGLGWRATLTRVVLPLAAPGLGAAATMVFISVVTELNATLLLSPIGTRTLATQVWSDTATLAFAAAAPYAALLVALSLGASGLLFLLLGRASVRN
>NZ_CP042164.1|WP_039361167.1|939238_940273_-|iron-ABC-transporter-substrate-binding-protein
MNTSPVSRPLRHLISAAAAALMLTGALHAARAHAATLTLYNAQHEQVVNQLVKDFEAQSGITVKVRSGEGPALAAQLVAEGDRTPADVYFTENSPELVLLDRKGLFAKTDAATLQSVPARFNPADGNWVGVLARENVLIYNTAKIQPQQLPASLLDLAKPEWKGKVGVAPSDADFLPLVSAVLALHGEAATLQWLKGLKANAQIFDDDEGVTAAVNRGGVLTGIVNNYYWDRLHAELGDKSTRSAIYHFGKGDVGGAVNVSGAAVLKASKHQPEAQKFVAYLVSERAQKLMAGGHISFEYPLHPGVAPDPILKPFNELTPPALTFEQLGDDSQAGKLLRQAGLL
>NZ_CP042164.1|WP_039361164.1|940338_941643_-|deferrochelatase/peroxidase-EfeB
MADDSNQPPRPARRGFLKAGGAAVAAGLAAASIPAAKAADAPAPAPAPAFAHDDVEPFYGKHQSGIATPQQRHAYFAALDLTTAQRADVIALLKTWTDAAARMTRGDTAQPLAPTGGDEVAPADGGDALGLGPARLTITFGFGPGMFVLAGKDRFGLAKHRPAALVDLPRFNGDQLLPEKTGGDLFIQACADDAQVAFHAVRQLVRLGAKATQMRWGQAGFTSGKPGETPRNLMGFKDGTMNPPMSDPAAMNEFVWAGSEGPAWMNGGTYTVVRRIRITLEHWDNTELGFQEQVVGRHKYSGAPLGQKNEFEALDLDAADKDGNPVIPDNSHARLASPQLNNGAQILRRAYSYNDSTNFYIERWPPWRQQTEYDAGLMFVAHQRDPRKGFIPINEKLAKLDIMNQFTTHVGSAIFACPPGAQPGSYIGAALFEA

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Crispr_ID: NZ_CP042164_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042164_2

1797297-1797498

Orphan

Consensus_repeat	Method
GCAAGACGGGCGGCTTCGTCGGCAGCAAC	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP042164_2

>merge|NZ_CP042164|2|1797297-1797498|PILER-CR
GACGGGCGGCTTCGTCGGCGTCAACCTGGGGCCCAACGCAACCGTCGACATGGCGGAGGCCCACGGTGCGGTGAGCGGCGGCCAGGGCAACATCGGCGGCTTCGTCGGCAGTCATTTCGGCGGACGGATTGCACATGCGGTCGCGCGCGGCAAGACGACGGGCGGCAACTACAGCAAGACGGGCGGCTTCGTCGGCAGCAAC

>NZ_CP042164|2|1|1797297-1797498|PILER-CR
GACGGGCGGCTTCGTCGGCGTCAACCTGG	GGCCCAACGCAACCGTCGACATGGCGGAGGCCCACGGTGCGGTGAGCGGCGGCCAGGGCAA
CATCGGCGGCTTCGTCGGCAGTCATTTCG	GCGGACGGATTGCACATGCGGTCGCGCGCGGCAAGACGACGGGCGGCAACTACAGCAAGACG
GGCGGCTTCGTCGGCAGCAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042164.1\|WP_039358697.1\|1794053_1794845_+\|fimbria/pilus-periplasmic-chaperone	unknown	unknown	gnl\|CDD\|225663
NZ_CP042164.1\|WP_039358692.1\|1797984_1799160_+\|type-1-fimbrial-protein	unknown	unknown	gnl\|CDD\|226069
NZ_CP042164.1\|WP_039358709.1\|1784152_1785067_+\|N-carbamoylputrescine-amidase	unknown	unknown	gnl\|CDD\|274553
NZ_CP042164.1\|WP_039358690.1\|1799341_1800157_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270407
NZ_CP042164.1\|WP_039358674.1\|1811534_1813988_+\|fimbrial-biogenesis-outer-membrane-usher-protein	unknown	unknown	gnl\|CDD\|225729
NZ_CP042164.1\|WP_039359018.1\|1790463_1791222_+\|fimbria/pilus-periplasmic-chaperone	unknown	unknown	gnl\|CDD\|225663
NZ_CP042164.1\|WP_039359016.1\|1791388_1794049_+\|fimbrial-biogenesis-outer-membrane-usher-protein	unknown	unknown	gnl\|CDD\|225729
NZ_CP042164.1\|WP_039358687.1\|1800251_1800974_+\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_CP042164.1\|WP_082139518.1\|1785077_1786190_+\|polyamine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270377
NZ_CP042164.1\|WP_039358681.1\|1804251_1805451_+\|MexX/AxyX-family-multidrug-efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|169982
NZ_CP042164.1\|WP_039358716.1\|1782038_1782968_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP042164.1\|WP_039358706.1\|1786266_1787379_+\|agmatine-deiminase-family-protein	unknown	unknown	gnl\|CDD\|377332
NZ_CP042164.1\|WP_039359012.1\|1808607_1810065_+\|efflux-transporter-outer-membrane-subunit	unknown	unknown	gnl\|CDD\|182103
NZ_CP042164.1\|WP_039358703.1\|1787528_1789052_+\|agmatine-deiminase-family-protein	unknown	unknown	gnl\|CDD\|377332
NZ_CP042164.1\|WP_039358699.1\|1789854_1790439_+\|type-1-fimbrial-protein	unknown	unknown	gnl\|CDD\|226069
NZ_CP042164.1\|WP_039358719.1\|1780647_1781952_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|182433
NZ_CP042164.1\|WP_039358684.1\|1803453_1804101_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182632
NZ_CP042164.1\|WP_039358675.1\|1810902_1811415_+\|fimbrial-protein	unknown	unknown	gnl\|CDD\|185131
NZ_CP042164.1\|WP_039359014.1\|1801850_1803113_-\|M23-family-metallopeptidase	unknown	unknown	gnl\|CDD\|366703
NZ_CP042164.1\|WP_039359015.1\|1800976_1801702_+\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836

Protein	Function_ID	Function_description	E-value
NZ_CP042164.1\|WP_039358697.1\|1794053_1794845_+\|fimbria/pilus-periplasmic-chaperone	gnl\|CDD\|225663	COG3121, FimC, P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion].	4.64247e-57
NZ_CP042164.1\|WP_039358692.1\|1797984_1799160_+\|type-1-fimbrial-protein	gnl\|CDD\|226069	COG3539, FimA, P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion].	1.33067e-07
NZ_CP042164.1\|WP_039358709.1\|1784152_1785067_+\|N-carbamoylputrescine-amidase	gnl\|CDD\|274553	TIGR03381, putative_carbon-nitrogen_hydrolase, N-carbamoylputrescine amidase. Members of this family are N-carbamoylputrescine amidase (3.5.1.53). Bacterial genes are designated AguB. The AguAB pathway replaces SpeB for conversion of agmatine to putrescine in two steps rather than one. [Central intermediary metabolism, Polyamine biosynthesis].	0
NZ_CP042164.1\|WP_039358690.1\|1799341_1800157_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270407	cd13689, PBP2_BsGlnH, Substrate binding domain of ABC glutamine transporter from Bacillus subtilis; the type 2 periplasmic-bindig protein fold. This group includes periplasmic glutamine-binding domain GlnP from Bacillus subtilis and its related proteins. The GlnP domain belongs to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.20112e-116
NZ_CP042164.1\|WP_039358674.1\|1811534_1813988_+\|fimbrial-biogenesis-outer-membrane-usher-protein	gnl\|CDD\|225729	COG3188, FimD, P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion].	0
NZ_CP042164.1\|WP_039359018.1\|1790463_1791222_+\|fimbria/pilus-periplasmic-chaperone	gnl\|CDD\|225663	COG3121, FimC, P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion].	6.81755e-71
NZ_CP042164.1\|WP_039359016.1\|1791388_1794049_+\|fimbrial-biogenesis-outer-membrane-usher-protein	gnl\|CDD\|225729	COG3188, FimD, P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion].	0
NZ_CP042164.1\|WP_039358687.1\|1800251_1800974_+\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	1.39042e-57
NZ_CP042164.1\|WP_082139518.1\|1785077_1786190_+\|polyamine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270377	cd13659, PBP2_PotF, The periplasmic substrate-binding component of an ABC putrescine transport system and related proteins; contains the type 2 periplasmic-binding fold. This group represents the periplasmic substrate-binding domain that serves as the primary polyamine receptor of ABC-type putrescine-preferential transporter from gram-negative bacteria. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.16199e-150
NZ_CP042164.1\|WP_039358681.1\|1804251_1805451_+\|MexX/AxyX-family-multidrug-efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|169982	PRK09578, PRK09578, MexX/AxyX family multidrug efflux RND transporter periplasmic adaptor subunit.	0
NZ_CP042164.1\|WP_039358716.1\|1782038_1782968_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.23398e-38
NZ_CP042164.1\|WP_039358706.1\|1786266_1787379_+\|agmatine-deiminase-family-protein	gnl\|CDD\|377332	pfam04371, PAD_porph, Porphyromonas-type peptidyl-arginine deiminase. Peptidyl-arginine deiminase (PAD) enzymes catalyze the deimination of the guanidino group from carboxy-terminal arginine residues of various peptides to produce ammonia. PAD from Porphyromonas gingivalis (PPAD) appears to be evolutionarily unrelated to mammalian PAD (pfam03068), which is a metalloenzyme. PPAD is thought to belong to the same superfamily as aminotransferase and arginine deiminase, and to form an alpha/beta propeller structure. This family has previously been named PPADH (Porphyromonas peptidyl-arginine deiminase homologs). The predicted catalytic residues in PPAD are Asp130, Asp187, His236, Asp238 and Cys351. These are absolutely conserved with the exception of Asp187 which is absent in two family members. PPAD is also able to catalyze the deimination of free L-arginine, but has primarily peptidyl-arginine specificity. It may have a FMN cofactor.	3.11567e-156
NZ_CP042164.1\|WP_039359012.1\|1808607_1810065_+\|efflux-transporter-outer-membrane-subunit	gnl\|CDD\|182103	PRK09837, PRK09837, Cu(I)/Ag(I) efflux RND transporter outer membrane protein.	9.83719e-111
NZ_CP042164.1\|WP_039358703.1\|1787528_1789052_+\|agmatine-deiminase-family-protein	gnl\|CDD\|377332	pfam04371, PAD_porph, Porphyromonas-type peptidyl-arginine deiminase. Peptidyl-arginine deiminase (PAD) enzymes catalyze the deimination of the guanidino group from carboxy-terminal arginine residues of various peptides to produce ammonia. PAD from Porphyromonas gingivalis (PPAD) appears to be evolutionarily unrelated to mammalian PAD (pfam03068), which is a metalloenzyme. PPAD is thought to belong to the same superfamily as aminotransferase and arginine deiminase, and to form an alpha/beta propeller structure. This family has previously been named PPADH (Porphyromonas peptidyl-arginine deiminase homologs). The predicted catalytic residues in PPAD are Asp130, Asp187, His236, Asp238 and Cys351. These are absolutely conserved with the exception of Asp187 which is absent in two family members. PPAD is also able to catalyze the deimination of free L-arginine, but has primarily peptidyl-arginine specificity. It may have a FMN cofactor.	1.66929e-93
NZ_CP042164.1\|WP_039358699.1\|1789854_1790439_+\|type-1-fimbrial-protein	gnl\|CDD\|226069	COG3539, FimA, P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion].	2.93197e-10
NZ_CP042164.1\|WP_039358719.1\|1780647_1781952_+\|MFS-transporter	gnl\|CDD\|182433	PRK10406, PRK10406, alpha-ketoglutarate transporter; Provisional.	0
NZ_CP042164.1\|WP_039358684.1\|1803453_1804101_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|182632	PRK10668, PRK10668, DNA-binding transcriptional repressor AcrR; Provisional.	2.94886e-23
NZ_CP042164.1\|WP_039358675.1\|1810902_1811415_+\|fimbrial-protein	gnl\|CDD\|185131	PRK15209, PRK15209, long polar fimbrial protein LpfA; Provisional.	1.72297e-27
NZ_CP042164.1\|WP_039359014.1\|1801850_1803113_-\|M23-family-metallopeptidase	gnl\|CDD\|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	1.91474e-45
NZ_CP042164.1\|WP_039359015.1\|1800976_1801702_+\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	3.08957e-57

>NZ_CP042164.1|WP_039358697.1|1794053_1794845_+|fimbria/pilus-periplasmic-chaperone
MDRSRFRFVPLARLSSRRGCRKRVAGRILRAAVLASVASVGTPRCEASLTVVGTRFVYPADARALTILARNSGSAPILVQAWLDDGDANADPSRLRVPFVVAPPLARLDPGQPLSIRVQGVGGGLATDRESCFWINLLEVPPAAPTGEPVLRIAYRFRMKLLVRPPGLRGEPDDAPNRLAWTRDGTQAAASIAASNPTPYYVTLTRLSVNGEPVALKHGAVDVAPFGRAEIPIDRQIGAGAIVFDAVDESGASHEYRAQAVPP
>NZ_CP042164.1|WP_039359016.1|1791388_1794049_+|fimbrial-biogenesis-outer-membrane-usher-protein
MFASVAMASGTNGFAATVAPADAVDAGALEDTRRSSANPPPSGSAGAETHFDDSMLMHGAGSEPIDTTPFAQPNAIVPGVYRADLIVNGQWRGVEDITFRHDARGDVLPCYDRALLQRVGIDLDRSARGQDASQPPNPMPDGLICDALSRYVPGGALSFDTAEQKLYLTAPQFYMRLAEQSTYVDPSNWTNGVPAAWLNYNASAFTTRSSGYEYSQLYTGLSMAASAGPIRIRHNGNLTWSQHDRARYQRGYVYAQTDLPAWRAQLLAGESSTSGAMFDAVSFRGVQIASDDRMLPDEQRYYAPVVRGVAQSNAKVSIYQRGYLVHETTVAPGPFAIDNLQAMSYGGDLNVTVTEANGETRSFVVPFATTVQLLRPGSTRFSVMAGQAIELGDDIGKQYVGQFTVQRGISNAMTAYGGAAFASRYQSVLTGVALNTPIGGFAADITVARTQPRGGERMNGSSIRVSYSKNLPNSGTNFSLLAYRYSTRGYLGLRDAMLLNGRSDQGAAAASFARLRDRVDLNVSQQIGRAGNIYANGSALSYWAGGGQTVSFTLGYSTQWRDATVTASVQRVRNLSTRDSSFGRGAGSTLVSLNVSIPLGRNSRRAPIFSSFMTHDSSTGTSATASLAGRFGERGDGSYSMAASYDGNNRASSGSFGIGYQRPAVSVSANLGIGRDYQQASANATGGLVLHPGGLTPAPTLSETIGVVRAPHARGALVANTSARVNRFGYAIVPSLIPYQLNKVDIDPKDVPEDVELKTVSRSVAPRSGSVVMLSYDTLKARALLIDAQLDDGRPLPFAARAVDARTGVALGAVGQGSRLFVRSAENDGQIRVEWGTRADQQCVVDYGIPAAQRSGTGYVALTGTCRAATLTPNVLGPQAERAGGR
>NZ_CP042164.1|WP_039359018.1|1790463_1791222_+|fimbria/pilus-periplasmic-chaperone
MNLTIRSLRLQAVAGVVAWAACATLAQAALLLDGTRVIFPEHDRDVTVRIKNAGTEPVLAQSWIDDGRADVPPEQMRTPFVVAPTLARVEAGRSAVLRITNMQAQLPADRESVFWLNVLEVPAVQQDTDNRLRFAFRTRIKLFYRPTSLANDVDTAADKLVWKVSADVPHTGGQPISLEVANPTPYYVSFGLVEGDVGGKFIPAGGGMVAPFGSQRFPLPGASGRSQRPTAVRYIAIDDYGGRSTITKKLAD
>NZ_CP042164.1|WP_039358699.1|1789854_1790439_+|type-1-fimbrial-protein
MKMNLLRGCVAAGIASAAFVPSVSHAFDGELAFYGSISDVTCNINGVAPGDGNRKEVQLGDRIGTDTFPQVGAVSTPATFNLVIGGNTGCTDGTKVLVEFDQRSNNINPVTGNLKLVGTKPAEGIEIQIKDAGNGKTGKIMLGQAQNLAEAQVATVASNTATLTYAAQYVSTAAKSAIKTGSGNSFIRYVLAYH
>NZ_CP042164.1|WP_039358703.1|1787528_1789052_+|agmatine-deiminase-family-protein
MMKRRTRASTGKRMRPTPDNGRRGFIRYSTAVLGLPLLGSLTACGGGDGAADAASTSPGTTSGTTPSTRQVKYRLPAEDAPHASTYMAFASGAEGIWMPVTPQSTDAGIDRVRADLMDVAKAIGATEPVDMLVLPADLDAARALLATASVANPDLHARYAARAAGAGGINLVPLADGFDDFWVRDTGCLFVRDSTNDNALNAVGFNFNGWGNANTDGAGMRPGATVPPEVEAGSNRSKAGKFFQPFGRDNAVAGWMAQRKGASLIRSTLTLEGGAIEFDGDATAILTESSVLHVNRNPQLFDIPNGAIANATLLPTAKDTVLAELQRTLGVRKVIWLPGTATYPRGSGVGGAGGAATPAGETDITNGHVDFYARFLAPGVVACCYDASNSTGERALTDANRQRLAGQTDANGRPLQIVELVPPANFGTSAGTSLNDRQMTNFAAGYINFYTCNGAIVMPKFNDAAADAAAVAAIRPYAGSRAIVQVDILGIASGGGGIHCSTREVPA
>NZ_CP042164.1|WP_039358706.1|1786266_1787379_+|agmatine-deiminase-family-protein
MTTRRQLLKRGLSVSGAALAAGALGGLLGRAAHAQQGATWHMPDEGAPHTATWMAFGPSEDIWGARLLPVARANLAAIAKAIAAHEPLKMLVREQDYAIASRLCGSSVELVQRPVDDLWMRDTGPVFVKNPSGQLGGVSFNFNGWGNKQEHDQDAEVAPFVAERAGVRLVDTRLVLEGGGIEVDGEGTAIITRSCVLNPNRNPGVSQAQCEVELSRLLGLKKIIWLPGIAGKDITDGHTDFYARFTSPGVVVAGLDTDPSSYDHAVTRQHLEILRKSTDAKGRPLKVVVLPGPKSVRHQYENDEFAAGYINFYVCNRAVIAPQFGDSRADRNTRDTLVDLFPGREIIQLNIDGIAAGGGGIHCTTQQQPA
>NZ_CP042164.1|WP_082139518.1|1785077_1786190_+|polyamine-ABC-transporter-substrate-binding-protein
MKRKGGLRFAVPGLALCVLAGTARADEEKVLNLYNWSNYFAPDTLAGFEKETGIKVRYDAYDSDETLQSKLLTGNSGYDLVWPTNDFMAKQIQAGVFRKLDRNRLPNLKYLDPSLLKQMAQSDPGNQYGVPYMWGTVGVGYDRARVRAILGKDMPADSLDLLFKPEIAARVSAKCGLGLQDSASTVLPLALRYIGHDPMHPSAQDYAAAQAMLMKIRPFIREFVNSSDANELIDGELCVTVGFSGAISLAAQKAKARDPKRDVVYDIPRIGTLMWFDAMVIPASAKHPDNAHAFINYILRPDVIAKISNSTRYANANQGALKLMDPALVRNPGIYPDEATRRTLFTPIAESPAAMRLEGRTWLGFKTARP
>NZ_CP042164.1|WP_039358709.1|1784152_1785067_+|N-carbamoylputrescine-amidase
MPSKHITVAAVQMASGSWNLEDNMATAERLIRAAAAQGANLVLCPELFAMPYFCLDQNVRHLELAQPFEGNAQIARFAALAGELGIVLPIGFFERAGNAAYNSIAVADADGRVLGVYRKTHIPDGPGYTEKFYFTPGDTGFKVWDTRFGRIGIGICWDQWYPETARSLALMGAEILCFPTIIGSEPFSSAFDSSGHWQRTMQGHAAANMVPVVAANRIGREVGIGNGDPEQQGLTGVFYGSSFIADHTGEKRAEANRTDEAVLVHTFDLDAIRANRQSWGFFRDRRPEMYRTLLTSDGVSSCYR
>NZ_CP042164.1|WP_039358716.1|1782038_1782968_-|LysR-family-transcriptional-regulator
MQRVPSLKLLTGFEAAARLGNFSRAADELHLSQSAISHQIQQLEAQLGQPLFRRRGRGVELTIAGEVLQRSVQRAMDTLRGGLDRIATYLNPGLVVLVCPAPLLHGWLQPRLEPLQQVLPDLCPLLSTDETARYVDEIDVDMTIGTRPMLQPGLLDIPFMRDEWVTVCATPLAEQLERVPRDEHPRHAGVICLEASLTDERLATVFRERLSAFRMHAIYDDQRLVLDAVLRGRGIACLPRLVAQAGIDQRTLTVLEGYPRLPGTTWWLSRMEGPSRSPIVERMFEWLVEQGSLSSASEPAPAHAPAPPA
>NZ_CP042164.1|WP_039358719.1|1780647_1781952_+|MFS-transporter
MDVQSDQAALSAHDTRRRVFAIVGASSGNLVEWFDFYIYSFCALYFAPAFFPSGNTTTQLLNTAGVFAAGFLMRPIGGWLFGRIADRHGRRNAMMISVLMMCGGSLVIAVLPTYAQIGALAPALLLVARLFQGLSVGGEYGTSATYMSEVALKGRRGFFASFQYVTLIGGQLCALLVLVILQQTLSADELKAWGWRIPFVVGAAAALISLYLRKSLDETSTSESRDKKNAGTIRGVWQHKGAFFTVVGFTAGGSLIFYTFTTYMQKYLVNTAGMHAKTASNVMTVALLVYMLMQPVFGALSDKIGRRTSMILFGSFAVIGTVPLMHALKDVTSPVAAFVLITVALAIVSFYTSISGLIKAEMFPPEVRAMGVGLSYAVANAIFGGSAEYVALWFKSIGSEETFYWYVTVLCAISLLVSWRMRDPSKEGYLRHEP
>NZ_CP042164.1|WP_039358692.1|1797984_1799160_+|type-1-fimbrial-protein
MKTIQWCSPGRIGRAIGRLTMAGYLVLAPCMQVMAQGSIGATALDCSFSNPEASPWKMITPLTSMTPQNAILYQRTVSLMVSFKYGTAPVAHELVSAAHWVPGAVVADGIAPTNVNGIGFKWVGVSGDDTERALQQHALPMATAKINLDRAGGGDTDSRFIRFRQYLVLDKPASQLPQEKLVVKNLPGNPTVAIYALDLPKGTATIGGTVTVPEQPTPANLCKQLKTFVGVGNVCIGSECEIHVPNRCEIQSNWIVPVTLGNFSISNFPSVNATSKPVSFDIALSQCAASAKPAISFRDKAAKPNPDKTLLQLSAPAGQTVARGFNIVMTNALTGERIAYGEPGAAAEYPMRRTGDMAVMPLRAQYIRTGGEGELAPGYAGGGAEFSFTFP
>NZ_CP042164.1|WP_039358690.1|1799341_1800157_+|ABC-transporter-substrate-binding-protein
MKFHTLATWLVGAALITAGTVAHADRLDDIKKAGVLRVATFDSNPPFGYVDGKSNHIVGLDVDYAKALADKLGVKLQLQPTNPANRIPFLTSGKVDLVLANFTITDERAKQVDFSIPYFSSGQQFLTKKGVLKSADQLNALRVGADKGTTNEITLREKFPKATIVAYDDTPFAFAALRAGNVQAITQDGPKLIGLLANVPDKQNYEIPAFTISNDYMGVGVPKGETRLLGFVNDTLKGLEASGRATQIYDAWFGPTTKTPLTRIFRIGDKT
>NZ_CP042164.1|WP_039358687.1|1800251_1800974_+|amino-acid-ABC-transporter-permease
MFGLAPKYLSWLWQGFLLTLGLAAASAVAATAGGLLLAVMRHARGMAPRTVAAAYVVTFRNTPLLVQLLFWYFGVASLLPDTWIAWLNARHALNVGPFTLAWPSFEFVAGWVGLSAYTAAFVAEECEAGLRGVRRAQHDAAAALGLTPMQSLRYVVLPQAVRIALPPLFGQYMNLVKNSSLAMAIGVAELSYASRQVETETFKTFAAFGVATVLYVAAVAAIEAGAYAATQWRDRLGAGR
>NZ_CP042164.1|WP_039359015.1|1800976_1801702_+|amino-acid-ABC-transporter-permease
MDLSLLFANLPYLLIGAFPDGPLGGAALSLLLAIASAAASAVLGIVLGVAMALARGPARVLLLAFIGFFRAIPVLMLIFWTYFLMPVLLHMDVPGLATVVCALALIGGAYLAHAVHAGIVAAGDGQWQAGLSLGLTRWQTVRYVLLPQAIRIMTPSFVNQWVALVKDTSLAYIVGVPELSFVATQVNNRLMVYPAPIFLFVALIYLVLCTSLDGAARWLLSRRPRAERIAQVAAEYTEPAR
>NZ_CP042164.1|WP_039359014.1|1801850_1803113_-|M23-family-metallopeptidase
MVKSAATPDAFAPGRAQRIARALVPAAVLGALAALGFAALPAVSQLPGAVDSGTAALPQRVLSDTPFPTAQHFVTSELARTIGERNDAGERNDRSQQPGLFAPLSAHRNEMLGYASLFQLAPPEHQQGMRAGNIELTLSDTLNRLDVPPEVRIQLGDLVTGKVAMRASAQRGDYYRVAYDTNNGTPHLTALELRVAGRTFGAIWFRAPGAEHGAYYALDGSPLEAAAFTMPVKWTRISSFFGERIHPLSQAMAFHTGVDLAAPSGTPVDAAADGVVSFVGTDPGGYGRYVIVDHADGYSTYYAHLSAFAHGLKTGETVKQGQRIGSVGMTGAATGPHLHFEVRVANNPVDPLVTLASAQTALSDMQLTAFRQEAAQWRFRLASINTTSFAFAQNDGPLWGDFATDSSTLRAVFNTHYSAS
>NZ_CP042164.1|WP_039358684.1|1803453_1804101_-|TetR-family-transcriptional-regulator
MARKTREESLAIKHRILDAAELVLLEKGVAQTAMADLAEAAGMSRGAVYGHYRNKMEVCLAMCDRAFARTSEGFDAGEGLPPLATLRRAASHYLQECGEPGPMQRVLVILYTKCEQSEENGALQRRRMLLELQMLRITKALLRRAIAAGEVAADLDVHLAAVYLVSLLEGVFASMIWTNRLRGNLWNDAEAMLDAGFDTVRTSAALRIRAHKLPG
>NZ_CP042164.1|WP_039358681.1|1804251_1805451_+|MexX/AxyX-family-multidrug-efflux-RND-transporter-periplasmic-adaptor-subunit
MNNNRSLLRHRLAPFALAAVLALAGCGKGDKDAAPEAAKQATVVTVRPTAVPMTVELPGRLDAYRQAEVRARVAGIVTARTYEEGQEVKQGAVLFRIDPAPLKAARDAAQGALAKAQAAALAATDKRRRYDDLVRDRAVSERDHTEAVAADTQAKAEVASAKAELARAQLQLDYATVTAPIAGRARRALVTEGALVGQSEATPLTTVEQLDPIYVNFSQPAADVDALRRAVKSGRATGIAQHDIAVTLLRADGTAYPLKGKLLFSDLAVDPTTDTVAMRALFPNPERELLPGAYVRIALDTAVDQRAILVPRDALLRTTDRMSVRVVGTNGKVKDVEVTADQMSGHDWRITRGLAGGERVIVDNAAQFAPDTAVKPVEKAPPSKAAPAAAASQAAARQT
>NZ_CP042164.1|WP_039359012.1|1808607_1810065_+|efflux-transporter-outer-membrane-subunit
MFALNARAALRAQVALAAALALAGCTLAPRYERPAAPVPATYAPVDGGAAPAAEASPADAALLDDWRTYFTDAALQAWIDAALANNRDLRVAAGRLEEARALYGVQRADRMPSVDANLGYDRTRQYDPVVRESAISGLYRAGVGISAYELDLFGRVRSLSDAALADYFATANAQRTVRIGVIADVAGAYVSERALHEQLALAQRTLDTRERMAALTQRRYAAGTSDAIELRSAEMLVASARASQAALQREHAQSVRALQLLAGDFARHVPDDTTALDALSIAPVAPGAPSALLERRPDIRQAEARLKAANAQIGAARAAFFPRITLTSDYGSVSDAFSSLFSGGTNVWTFAPRLTLPIFAGGRNRANLDVAKARKHIAVADYEKTVQTAFREVADAFAARDWIDRQLAAQQDVYAADGARLKLAERRYAGGVATYLELLDAQRSTYESGQELIRLKQLRLANAITLYRALGGGWSPASAEAAASA
>NZ_CP042164.1|WP_039358675.1|1810902_1811415_+|fimbrial-protein
MKKSILTAVALAALSTSAFAAGTGTINFTGEIVAGACGIDSGSVNQTVNLGKVPTNVFKQAGDKSTPTNFDIKLTDCDTSVAQNAYFTFTGTSSAGQPKLLATIGSATNVGIRLQAASGEYLDNGAEQKAPTVLQNGTNIARFAAMYEATAAGVTPGTADGVANFTVRYQ
>NZ_CP042164.1|WP_039358674.1|1811534_1813988_+|fimbrial-biogenesis-outer-membrane-usher-protein
MLVVGSQSHATEFNSSFLNIDGSNNVDLSQFSQADFTLPGEYMLDVQVNDLFYGLQAIEFIAVDTSGAGKPCLPPELVAQFGLKPSLLKDLPRFQGGRCVDLGAIEGATVRYLKSDGRLKITIPQAALEFTDSTYLPPSRWSEGIPGAMLDYRVIANTNRNFGTGGRQTNSIQAYGTVGANWDAWRFRGDYQAQSNVGNTAYADRTFRFSRLYAFRALPSIQSTVTFGDDYLTSDIFDTFALTGASIRSDDRMLPPSLRGYAPLISGVARTNATVTVSQAGRVLYVTRVSPGAFALQNINTSVQGTLDVAVEEEDGSVQRFQVTTAAVPFLARAGQLRYKAAVGKPRQFGGAGITPFFGFGEIAYGLPFDVTAYGGFIAASGYTSIALGLGRDFGAFGALSADVTHARAKLWWNGATRNGNSYRINYSKHFDGLDADVRFFGYRFSEREYTNFAQFSGDPTAYGLANSKQRYSATLSKRFGDTSTYFSYDQTTYWERANEQRVGLTLTRAFSIGTLRNLNVSVSAFRTQSAGASGNQVSVTATLPIGGRHTVTSNLTTGSGSTSVNAGYIYDDPSGRTYQVNAGATDGRASANASYRQRSSAYQLTAQASTLANAYAAASLEVDGSFVATQYGVSAHANGNAGDTRLLVSTDGVPDVPLSGTLSHTDSRGYAVLDGISPYNVYDATVNVEKLPLEVQVTNPIQRMVLTDGAIGFVKFSAARGSNLYLTLTDPAGKPLPFGASVQDVANGKELGIVGEGGAAFLTQVQPKSTLAVRAGERTLCTIDALPNQLQLEGTPIPVTCQTPGESHAAAARVER

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

446325 : 516322

Acinetobacter_phage(40.0%)

plate,integrase,tRNA

attL 455758:455774|attR 522079:522095

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039352024.1\|446325_447672_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_039352027.1\|447775_448387_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_039352030.1\|448760_449390_+	hypothetical protein	NA	NA	NA	NA
WP_027783377.1\|449436_449952_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_006477094.1\|449967_451458_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_006477093.1\|451528_452032_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_021161818.1\|452094_452580_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_039352038.1\|452657_454493_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_039352040.1\|454456_455557_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_039352044.1\|455600_458270_+	type VI secretion system ATPase TssH	A0A223W0B1	Agrobacterium_phage	1.7e-89	31.8
455758:455774	attL	NA	NA	NA	NA
WP_039352046.1\|458312_459434_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_039352052.1\|462113_463163_+	DUF4123 domain-containing protein	NA	NA	NA	NA
WP_082139503.1\|463303_464239_+	DUF3304 domain-containing protein	NA	NA	NA	NA
WP_039352058.1\|464225_466487_+	hypothetical protein	NA	NA	NA	NA
WP_039352061.1\|466568_467531_-	OmpA family protein	NA	NA	NA	NA
WP_039352064.1\|467535_468525_-	type VI secretion system-associated protein TagF	NA	NA	NA	NA
WP_039352067.1\|468521_472466_-	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_039352071.1\|472767_473613_-	M15 family metallopeptidase	NA	NA	NA	NA
WP_039352076.1\|473734_474691_+	hypothetical protein	NA	NA	NA	NA
WP_039352239.1\|474897_475923_+	transporter	NA	NA	NA	NA
WP_076841682.1\|475947_476100_-	DUF1427 family protein	NA	NA	NA	NA
WP_039352079.1\|476124_477102_-	zinc-binding alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_039352081.1\|477263_478184_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_039352084.1\|478308_480477_-	peptidase M1	A0A0P0IY26	Acinetobacter_phage	5.7e-51	26.7
WP_039352087.1\|481121_481616_+	Water stress and hypersensitive response domain-containing protein	NA	NA	NA	NA
WP_039352090.1\|481749_482883_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_039352243.1\|482972_483863_+	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_039352093.1\|483942_484515_-	DUF1415 domain-containing protein	NA	NA	NA	NA
WP_039352095.1\|484570_485191_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_039352098.1\|485410_486694_+	MFS transporter	NA	NA	NA	NA
WP_039352100.1\|486858_487464_+	nitroreductase family protein	NA	NA	NA	NA
WP_039352103.1\|487651_488902_+	Hsp70 family protein	NA	NA	NA	NA
WP_076841766.1\|489420_489642_-	hypothetical protein	NA	NA	NA	NA
WP_039352109.1\|489624_491223_+	APC family permease	NA	NA	NA	NA
WP_039352112.1\|491334_492126_-	dioxygenase	NA	NA	NA	NA
WP_039352114.1\|492336_492933_-	UbiX family flavin prenyltransferase	NA	NA	NA	NA
WP_021161789.1\|492961_493273_-	Grx4 family monothiol glutaredoxin	NA	NA	NA	NA
WP_039352118.1\|493348_494191_-	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_039352121.1\|494198_495281_-	peptide chain release factor 1	A0A0S4KWG0	Pseudomonas_phage	6.7e-08	46.6
WP_039352123.1\|495374_496673_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_039352126.1\|496699_497461_-	response regulator transcription factor	NA	NA	NA	NA
WP_039352130.1\|497632_497887_+	hypothetical protein	NA	NA	NA	NA
WP_039352246.1\|497905_499720_+	aminopeptidase P family protein	A0A0P0I8D7	Acinetobacter_phage	2.3e-170	49.7
WP_039352132.1\|499775_500327_+	cysteine hydrolase	NA	NA	NA	NA
WP_039352135.1\|500323_500947_+	HAD-IA family hydrolase	NA	NA	NA	NA
WP_039352138.1\|501083_502751_-	energy-dependent translational throttle protein EttA	A0A2K9L0W2	Tupanvirus	5.8e-43	27.7
WP_039352141.1\|502955_503264_-	DUF3761 domain-containing protein	NA	NA	NA	NA
WP_039352144.1\|503344_504262_-	transcriptional regulator GcvA	NA	NA	NA	NA
WP_039352147.1\|504454_505774_+	MFS transporter	NA	NA	NA	NA
WP_039352150.1\|505856_506201_+	hypothetical protein	NA	NA	NA	NA
WP_039352153.1\|506615_508007_+	GABA permease	NA	NA	NA	NA
WP_076841684.1\|508286_508787_+	glycoside hydrolase family protein	NA	NA	NA	NA
WP_039352156.1\|508795_509209_+	DUF1311 domain-containing protein	NA	NA	NA	NA
WP_039352159.1\|509478_510690_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_144610271.1\|510885_511335_-	hypothetical protein	NA	NA	NA	NA
WP_135370752.1\|511318_512905_-	hypothetical protein	NA	NA	NA	NA
WP_039352162.1\|513375_515064_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_039352164.1\|515056_516322_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
522079:522095	attR	NA	NA	NA	NA

DBSCAN-SWA_2

802809 : 811910

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039361356.1\|802809_804762_+	molecular chaperone DnaK	A0A1V0SH73	Hokovirus	1.2e-148	49.8
WP_039361355.1\|805029_806166_+	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	1.6e-23	27.0
WP_039361354.1\|806179_808114_+	bifunctional anthranilate synthase component I family protein/class IV aminotransferase	S4VT78	Pandoravirus	1.4e-56	36.4
WP_039361353.1\|808231_809047_-	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0N7HVJ8	Ostreococcus_lucimarinus_virus	1.5e-36	32.5
WP_039361352.1\|809092_809779_-	deoxynucleoside kinase	A0A0M3UL55	Enterococcus_phage	2.7e-07	25.9
WP_039361350.1\|809775_810318_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_039361348.1\|810353_811910_-	polynucleotide adenylyltransferase PcnB	H7BUW3	unidentified_phage	1.8e-22	30.5

DBSCAN-SWA_3

961455 : 973500

Enterobacteria_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039361120.1\|961455_962517_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	8.6e-85	47.9
WP_039361116.1\|962528_963422_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	2.8e-97	57.5
WP_039361113.1\|963406_963958_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	3.2e-51	53.0
WP_039361111.1\|963950_964850_+	dTDP-4-dehydrorhamnose reductase	I7HXC9	Enterobacteria_phage	2.2e-25	35.8
WP_039361109.1\|965235_966684_+	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	A0A1V0SH58	Hokovirus	1.1e-53	28.8
WP_039361107.1\|966683_967478_+	ABC transporter permease	NA	NA	NA	NA
WP_039361104.1\|967477_968701_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.5e-11	26.8
WP_076841713.1\|968697_973500_+	FkbM family methyltransferase	Q684B1	Sulfolobus_virus	6.2e-05	40.3

DBSCAN-SWA_4

3601930 : 3667935

Escherichia_phage(33.33%)

integrase,tRNA,transposase

attL 3595639:3595655|attR 3661609:3661625

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3595639:3595655	attL	NA	NA	NA	NA
WP_039364530.1\|3601930_3602959_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	7.3e-73	44.7
WP_039364532.1\|3602955_3603729_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.2e-81	56.5
WP_012431368.1\|3605418_3606156_-	hypothetical protein	NA	NA	NA	NA
WP_012431366.1\|3607006_3607198_+	hypothetical protein	NA	NA	NA	NA
WP_012431365.1\|3607581_3608394_-	metal ABC transporter permease	NA	NA	NA	NA
WP_012431364.1\|3608396_3609317_-	metal ABC transporter permease	NA	NA	NA	NA
WP_012431363.1\|3609313_3610135_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.9e-16	29.2
WP_106352142.1\|3610139_3611099_-	cation ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_012431361.1\|3611230_3612217_+	GTP-binding protein	NA	NA	NA	NA
WP_012431360.1\|3613344_3613926_-	hypothetical protein	NA	NA	NA	NA
WP_039364538.1\|3614789_3615152_-	hypothetical protein	NA	NA	NA	NA
WP_039364540.1\|3615159_3616422_-	MFS transporter	NA	NA	NA	NA
WP_012431358.1\|3616529_3617336_-	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_012431357.1\|3617353_3617917_-	hypothetical protein	NA	NA	NA	NA
WP_134163151.1\|3617913_3618180_-	hypothetical protein	NA	NA	NA	NA
WP_083772028.1\|3618606_3618903_+	hypothetical protein	NA	NA	NA	NA
WP_012431356.1\|3619676_3620807_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_083772027.1\|3620799_3622437_-\|tRNA	methionine--tRNA ligase	NA	NA	NA	NA
WP_106352135.1\|3622484_3623549_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_012431353.1\|3623548_3623917_-	cupin domain-containing protein	NA	NA	NA	NA
WP_106352143.1\|3623954_3625250_-	SidA/IucD/PvdA family monooxygenase	NA	NA	NA	NA
WP_012431351.1\|3625395_3626787_-	MFS transporter	NA	NA	NA	NA
WP_012431350.1\|3626903_3627659_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012431349.1\|3627686_3628355_-	glutathione S-transferase family protein	NA	NA	NA	NA
WP_012431348.1\|3628422_3629862_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_012431347.1\|3629918_3630380_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_012431346.1\|3631531_3632689_+	DNA polymerase IV	NA	NA	NA	NA
WP_012431345.1\|3632891_3633551_-	hypothetical protein	NA	NA	NA	NA
WP_106352144.1\|3634721_3635330_-	LysE family translocator	NA	NA	NA	NA
WP_012431343.1\|3635374_3636451_-	glycine hydroxymethyltransferase	NA	NA	NA	NA
WP_012431342.1\|3636720_3637182_+	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_012431341.1\|3637248_3638466_-\|integrase	tyrosine-type recombinase/integrase	F1BUS9	Erwinia_phage	4.0e-70	44.6
WP_039364547.1\|3638520_3639264_-	hypothetical protein	NA	NA	NA	NA
WP_012431339.1\|3639359_3639578_+	hypothetical protein	NA	NA	NA	NA
WP_012431338.1\|3639681_3640110_-	hypothetical protein	NA	NA	NA	NA
WP_012431337.1\|3640475_3640772_+	H-NS histone family protein	NA	NA	NA	NA
WP_012431336.1\|3641044_3641923_+	hypothetical protein	NA	NA	NA	NA
WP_012431335.1\|3641976_3643176_-	hypothetical protein	NA	NA	NA	NA
WP_049868870.1\|3643199_3644252_-	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_012431332.1\|3644445_3645528_-	hypothetical protein	NA	NA	NA	NA
WP_012431331.1\|3645560_3645749_-	hypothetical protein	NA	NA	NA	NA
WP_039364586.1\|3645770_3647621_-	carbamoyltransferase	A0A1B1IVF2	uncultured_Mediterranean_phage	1.1e-58	32.8
WP_012431329.1\|3647673_3649941_-	iron-containing redox enzyme family protein	NA	NA	NA	NA
WP_012431328.1\|3650216_3651185_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_012431327.1\|3651338_3652799_-	sodium:sulfate symporter	NA	NA	NA	NA
WP_012431326.1\|3652904_3653699_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012431324.1\|3654125_3654410_-	hypothetical protein	NA	NA	NA	NA
WP_011493638.1\|3655140_3655974_+	DUF945 domain-containing protein	K4F5L3	Cronobacter_phage	1.5e-39	37.2
WP_012431321.1\|3656359_3657361_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_012431320.1\|3657357_3658707_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_012431319.1\|3658703_3659930_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_012431318.1\|3662316_3662562_+	hypothetical protein	NA	NA	NA	NA
3661609:3661625	attR	NA	NA	NA	NA
WP_039364591.1\|3662757_3662964_+	hypothetical protein	NA	NA	NA	NA
WP_012431316.1\|3663078_3663798_-	hypothetical protein	NA	NA	NA	NA
WP_012431315.1\|3663790_3664495_-	P-loop NTPase	NA	NA	NA	NA
WP_012431314.1\|3664504_3664954_-	hypothetical protein	NA	NA	NA	NA
WP_021162791.1\|3666172_3666541_+	hypothetical protein	NA	NA	NA	NA
WP_012431312.1\|3666834_3667935_+\|transposase	IS110 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP042165

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP042165_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042165_1

1940884-1941334

Orphan

Consensus_repeat	Method
AGCAATGTCGGCGGCCTCGTCGGCA	CRISPRCasFinder
AGCAATGTCGGCGGCCTCGTCGGCAGCAACG	PILER-CR

5 spacers

The CRISPR arrays of NZ_CP042165_1

>merge|NZ_CP042165|1|1940884-1941334|CRISPRCasFinder,PILER-CR
AGCTCGGCAGGCGGTCTCGTCGGGTACAACGTGGGCCGCATCCTCACGTCGAGCGCCAAGGGCAACGTATCGACCCGGTACTCGAGCCGCGCAGGCGGCCTCGTCGGACGCAACTTCGGCACGATCGCCGATTCCCGTGCGACGGGCCTGGTGAAGGCGGGCGACTTCTCGTCGGTCGGTGGCCTCGTCGGCAGCAACGAGCGGGGCAGCATCGTCCGGTCGACGGCGTCGGGCGACGTCGAAGGCGGCGCGCAGAGCAATGTCGGCGGCCTCGTCGGCAGCCAGACCGGGACTGTCGACCAGTCGCGTGCGACGGGCTCCGCCCGGGGCGGCTTCGCCAGCTATGTCGGCGGCCTCGTCGGCAACAACGGCGGCACCATCACCGCGTCGTCGTCGTCGAACGGCACCGTATCCGGCGGCCAGTACGCGCGGCTCGGCGGCCTCGTCGGCG

>NZ_CP042165|1|1|1940884-1941334|CRISPRCasFinder
AGCTCGGCAGGCGGTCTCGTCGGGT	ACAACGTGGGCCGCATCCTCACGTCGAGCGCCAAGGGCAACGTATCGACCCGGTACTCG
AGCCGCGCAGGCGGCCTCGTCGGAC	GCAACTTCGGCACGATCGCCGATTCCCGTGCGACGGGCCTGGTGAAGGCGGGCGACTTC
TCGTCGGTCGGTGGCCTCGTCGGCA	GCAACGAGCGGGGCAGCATCGTCCGGTCGACGGCGTCGGGCGACGTCGAAGGCGGCGCGCAG
AGCAATGTCGGCGGCCTCGTCGGCA	GCCAGACCGGGACTGTCGACCAGTCGCGTGCGACGGGCTCCGCCCGGGGCGGCTTCGCC
AGCTATGTCGGCGGCCTCGTCGGCA	ACAACGGCGGCACCATCACCGCGTCGTCGTCGTCGAACGGCACCGTATCCGGCGGCCAGTAC
GCGCGGCTCGGCGGCCTCGTCGGCG

>NZ_CP042165|1|1|1941058-1941253|PILER-CR
GTCGGTGGCCTCGTCGGCAGCAACGAGCGGG	GCAGCATCGTCCGGTCGACGGCGTCGGGCGACGTCGAAGGCGGCGCGCAGAGCAAT
GTCGGCGGCCTCGTCGGCAGCCAGACCGGGA	CTGTCGACCAGTCGCGTGCGACGGGCTCCGCCCGGGGCGGCTTCGCCAGCTATGTCG
GCGGCCTCGTCGGCAACAACG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042165.1\|WP_039369774.1\|1955190_1958193_-\|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl\|CDD\|274362
NZ_CP042165.1\|WP_039371458.1\|1925380_1926520_+\|acyltransferase	unknown	unknown	gnl\|CDD\|224748
NZ_CP042165.1\|WP_039371462.1\|1926649_1927390_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042165.1\|WP_039371474.1\|1931913_1933635_-\|ubiquinone-dependent-pyruvate-dehydrogenase	unknown	unknown	gnl\|CDD\|181661
NZ_CP042165.1\|WP_039369777.1\|1954166_1954715_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042165.1\|WP_039369787.1\|1948171_1948813_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237939
NZ_CP042165.1\|WP_082139546.1\|1936207_1937917_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NZ_CP042165.1\|WP_046197026.1\|1944689_1947740_+\|filamentous-hemagglutinin-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|273865
NZ_CP042165.1\|WP_039369805.1\|1951757_1953917_-\|fimbrial-protein	unknown	unknown	gnl\|CDD\|374909
NZ_CP042165.1\|WP_148668959.1\|1951066_1951753_-\|pilus-assembly-protein	unknown	unknown	gnl\|CDD\|237939
NZ_CP042165.1\|WP_135370735.1\|1949491_1950511_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042165.1\|WP_046197024.1\|1948937_1949444_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP042165.1\|WP_052760189.1\|1950590_1951067_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237939
NZ_CP042165.1\|WP_039371476.1\|1933879_1934380_-\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|183009
NZ_CP042165.1\|WP_039371468.1\|1930435_1931026_-\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|226472
NZ_CP042165.1\|WP_046544080.1\|1941629_1944536_+\|filamentous-hemagglutinin-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|214908
NZ_CP042165.1\|WP_039371479.1\|1934577_1935594_+\|1-aminocyclopropane-1-carboxylate-deaminase	unknown	unknown	gnl\|CDD\|183494
NZ_CP042165.1\|WP_039371471.1\|1931367_1931808_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|236715
NZ_CP042165.1\|WP_039371485.1\|1928847_1930281_-\|sulfatase-like-hydrolase/transferase	unknown	unknown	gnl\|CDD\|224699
NZ_CP042165.1\|WP_039371465.1\|1927423_1928815_-\|sulfatase-like-hydrolase/transferase	unknown	unknown	gnl\|CDD\|224699

Protein	Function_ID	Function_description	E-value
NZ_CP042165.1\|WP_039369774.1\|1955190_1958193_-\|hybrid-sensor-histidine-kinase/response-regulator	gnl\|CDD\|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	4.01216e-88
NZ_CP042165.1\|WP_046197026.1\|1944689_1947740_+\|filamentous-hemagglutinin-N-terminal-domain-containing-protein	gnl\|CDD\|273865	TIGR01901, Heme/hemopexin-binding_protein, filamentous hemagglutinin family N-terminal domain. This model represents a conserved domain found near the N-terminus of a number of large, repetitive bacterial proteins, including many proteins of over 2500 amino acids. Members generally have a signal sequence, then an intervening region, then the region described by this model. Following this region, proteins typically have regions rich in repeats but may show no homology between the repeats of one member and the repeats of another. A number of the members of this family have been designated adhesins, filamentous haemagglutinins, heme/hemopexin-binding protein, etc.	2.13638e-20
NZ_CP042165.1\|WP_052760189.1\|1950590_1951067_-\|hypothetical-protein	gnl\|CDD\|237939	PRK15308, PRK15308, fimbrial protein TcfA.	6.30767e-08
NZ_CP042165.1\|WP_039371474.1\|1931913_1933635_-\|ubiquinone-dependent-pyruvate-dehydrogenase	gnl\|CDD\|181661	PRK09124, PRK09124, ubiquinone-dependent pyruvate dehydrogenase.	0
NZ_CP042165.1\|WP_039369787.1\|1948171_1948813_-\|hypothetical-protein	gnl\|CDD\|237939	PRK15308, PRK15308, fimbrial protein TcfA.	2.65508e-13
NZ_CP042165.1\|WP_082139546.1\|1936207_1937917_+\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	4.77376e-114
NZ_CP042165.1\|WP_046544080.1\|1941629_1944536_+\|filamentous-hemagglutinin-N-terminal-domain-containing-protein	gnl\|CDD\|214908	smart00912, Haemagg_act, haemagglutination activity domain. This domain is suggested to be a carbohydrate- dependent haemagglutination activity site. It is found in a range of haemagglutinins and haemolysins.	7.14072e-21
NZ_CP042165.1\|WP_039369805.1\|1951757_1953917_-\|fimbrial-protein	gnl\|CDD\|374909	pfam16967, TcfC, E-set like domain. TcfC is a family of bacterial fimbrial proteins. These sit in the outer bacterial membrane surrounding the RcpA proteins of the fimbrial shaft. This family is from Gamma-proteobacteria. This domain represents an immunoglobulin like E-set domain.	1.55611e-11
NZ_CP042165.1\|WP_148668959.1\|1951066_1951753_-\|pilus-assembly-protein	gnl\|CDD\|237939	PRK15308, PRK15308, fimbrial protein TcfA.	2.0081e-15
NZ_CP042165.1\|WP_039371476.1\|1933879_1934380_-\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|183009	PRK11169, PRK11169, leucine-responsive transcriptional regulator Lrp.	7.82215e-45
NZ_CP042165.1\|WP_039371468.1\|1930435_1931026_-\|methyltransferase-domain-containing-protein	gnl\|CDD\|226472	COG3963, COG3963, Phospholipid N-methyltransferase [Lipid metabolism].	1.59005e-37
NZ_CP042165.1\|WP_039371458.1\|1925380_1926520_+\|acyltransferase	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	1.11002e-23
NZ_CP042165.1\|WP_039371479.1\|1934577_1935594_+\|1-aminocyclopropane-1-carboxylate-deaminase	gnl\|CDD\|183494	PRK12390, PRK12390, 1-aminocyclopropane-1-carboxylate deaminase; Provisional.	0
NZ_CP042165.1\|WP_039371471.1\|1931367_1931808_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|236715	PRK10562, PRK10562, putative acetyltransferase; Provisional.	4.59687e-35
NZ_CP042165.1\|WP_039371485.1\|1928847_1930281_-\|sulfatase-like-hydrolase/transferase	gnl\|CDD\|224699	COG1785, PhoA, Alkaline phosphatase [Inorganic ion transport and metabolism].	8.34452e-130
NZ_CP042165.1\|WP_039371465.1\|1927423_1928815_-\|sulfatase-like-hydrolase/transferase	gnl\|CDD\|224699	COG1785, PhoA, Alkaline phosphatase [Inorganic ion transport and metabolism].	2.56861e-123

>NZ_CP042165.1|WP_082139546.1|1936207_1937917_+|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MRRARPLLRSDSIADRRSGRLRIACLTSLALSLHGIAHAQAQVPNAGQSLRDVETLRPTLPVPAAPDLAMPPSDEAPSSATAEGPRIPVSAFAIEGNAAIPAARLDALLVDLVGRELSFGDLQQAAARITAYYREHGYVLARAYLPHQDIEHGVVRIAVVEGRYGQLELHNRTRVLDRALRQPLASLQPGEIVSGNRLERSLMLLNEMPGVDAKGTLRPGAEPGTTDLVIDAERSRFATGSVEFDNFGDPLTGRYRATGSIDVNAPLRLGDRFSLRGLTSNTNQRYYRASYQVPVGPASTRVGIAYSDMNYRIGGSLKELRYHGGADVRSAFVTQPLLRSRRTSVDAQVTYENKHLRDVYGIFDVVGDKTVDLWSFGVSGNRQDGFGGGGRTGFSATVGIGHLSSNDPLDMNYYAHTLGQFAKLNINALRLQALGSRFQLYTQFSAQLSSRNLDSSEKFNLGGPYGVRAFALGAGSGDQGWQATAELRYLVAPGWQLSTFADTGRIQLSKQRWSRERNTVQLSSLGIGASWYGSRHQVSVTAALPVGYTDQVASPTRSPSVWLQAAQYF
>NZ_CP042165.1|WP_039371479.1|1934577_1935594_+|1-aminocyclopropane-1-carboxylate-deaminase
MNLQRFSRYPLTFGPTPIQPLKRLSAHLGGKVELYAKREDCNSGLAFGGNKTRKLEYLVPDALAQGADTLVSIGGVQSNQTRQVAAVAAHLGMKCVLVQEHWVNYEDPVYDRVGNIQLSRMMGADVRLVSDGFDIGIRRSWEEAMESVRQAGGKPYPIPAGCSEHPLGGLGFVGFAEEVRAQEAQLGFRFDYIVVCSVTGSTQAGMVVGFAADGRADRVIGIDASATPERTHEQITRIARHTAELVDLGRPITAADVVLDTRYAGPEYGLPNDGTLEAIRLCARLEGMLTDPVYEGKSMHGMIDKVRLGEFEPGSKVLYAHLGGVPALSAYSGIFREG
>NZ_CP042165.1|WP_039371476.1|1933879_1934380_-|Lrp/AsnC-family-transcriptional-regulator
MKLDRGRASPTDAAPALDRIDRAILRQLQQDASISNVSLAAKVKLSAPACLRRVERLKEMGLIRGIVALLDPKPLGAGMLVVIGFVLDRSTPEAFAAFEKAAQKVSGCVECHVVTGEFDYFMLVRTRDNDSFNRLHAEQLLYLPGVRQVRSFMVLKEILSTHALPL
>NZ_CP042165.1|WP_039371474.1|1931913_1933635_-|ubiquinone-dependent-pyruvate-dehydrogenase
MAKQTMAEYLAKTLAAAGVERIWGVTGDSLNGLSFSLGQIGSIRWMHTRHEESAAFAAGADAASTGRLAVCAGSCGPGNLHLINGLYDCHRNHQPVLAIAAHIPSTEIGLGYFQETHPQELFRECSHFAELVTNASQFPRVLARAMRTAIEERGVAVIVLPGDIALGDGPDELPAWSESAPPSILPADADLDRLAALLNASDAVTLLCGSGTQSAHDEVVALADTLGAPVVHALRGKQFVEWDNPFDVGMTGLIGFSSGYHAMESCDTLLMLGTDFPYRPFYPSNAKVAQIDWKGSQLGHRAPLALGLVGTVKETIAALLPRLTRKTQRRFLENALKHYAAARKGLDDLAVAEPPGRAIHPQYLTKIVDEVAAEDAIFTADVGTPTLWAARYLTMNGKRQLHGSFNHGSMANAMPQALGAQGAHPGRQVVSLSGDGGLSMLLGDLLTARQLKLPIKIVVYNNSLLGFVSMELKAAGYLDTNVDLSPTDFAAIAKGAGIFSVRVEHSENVEEALRMAFAHDGPAVVDVVTSKYELAMPPKIELAHAKGFSLFMLRAILSGRGDEIVELARTNLR
>NZ_CP042165.1|WP_039371471.1|1931367_1931808_-|GNAT-family-N-acetyltransferase
MAIEIRAYEASDLHTLSAIWFDASLLAHAFLGEARLREQRALIEAVYLPKAETWVACRAGEPVGFIGLLDDSIGGLFVAPAMHGHGIGRALVEHALALKGALDLEVYADNLDARAFYARLGFDEISRRDGDDEGLPFVNILMRSTR
>NZ_CP042165.1|WP_039371468.1|1930435_1931026_-|methyltransferase-domain-containing-protein
MMWPNAWRVSALFVREWVGRPAAVGALCPSSRQLAREMADAVPDGDGLVVELGGGTGAITAALLERGVAPRRLVVVERSPAFVQHLRRRFPGITIVSGDARQLERLLPPDAHVDAIVSCLPLRTLPRQDVAAIVDQCHRVLSADGVMIQFTYDLRPPGRHPLGDSAFVACGSRIVWANIPPARIVTVRSVTAEHAE
>NZ_CP042165.1|WP_039371485.1|1928847_1930281_-|sulfatase-like-hydrolase/transferase
MNRIKLAALLCAGAFALAGCGSDDGPTSTAPGPVQAAARNVIFFLGDGMGITTMTAARIYAVGEDGALTIDTLPETAFVKTYSNDAQVTDSAPSMSAYMTGVKTNNEVISMTPDTKAIEPTASLTGNCGANNGKSATTLLEIAKAKGLATGVVTTTRVTHATPAATYAHVCHRDAENDIAAQLVPGGAGYNGALGDGVDVVLGGGTQFFVPKDGGGKRTDGRNLVNELKAKGYAVAQNRDDLLAADATKGGKLVGLFSSSHMSYDLDRGATKEPSLTDMATRALDVLQKNPNGYFLMVEGGRIDHALHDTNAKRALQDTVAFDNAIKATIDKVRQTDPDLKNTLIVVTADHDHTLVLNGYAARTGKTEAGKPGVLGVLRSYQTGSVAKDADGAPYTIIGFGNGENRVQGSRAGTALTDAVTGADDYRQEAVVRMDKGSETHGGTDVFLGAIGRGADAFHGVIENNKVFELVRNAVQL
>NZ_CP042165.1|WP_039371465.1|1927423_1928815_-|sulfatase-like-hydrolase/transferase
MSTIKCIAAALAVAGFACGAAQAAGQAKNVIFFLGDGMGPTTVTASRIYKVGESGQLTMEKLARTARVKTFSNDAQTTDSAPSMAAYMTGVKMNNEVLSMSSDTRAVAPGNDANGNKTVNNCAPGNGQPVATLLELAKARGKAVGAITTTELTHATPAATYSHICHRDAQYDIAAQAAPGGAGYNAALGDGVDVLMGGGRNHWTPFDPVANKRGRADGRNLLNEMKAKGYTVVATRDQLAQAGNGKLVGLFSSTSHLEYELDRVAGKGEGPTQPSLAEMTSKAIDVLSKNSNGYFLMVEGGRIDHALHGTNAKRALEDTAAFDEAIRVALSKVDLSNTLIVVTADHDHTMTINGYSKRGNPILDISRNYRDGQPSKDADGNTYTTLVFGNGANRPNVRASVDSATATNDAYLQEVGVRMGSAGSETHGGGDVMLFADGADAKAFKGTIDNTKVFGLVRSAFGF
>NZ_CP042165.1|WP_039371462.1|1926649_1927390_-|hypothetical-protein
MKRQLLYALACGWVALPALAAADLDAVLVHESRTVSADGVTRTTMYRERMVRRDAHVWVERVLPVAAAGGHGNDHDHDHDHDAGARTGVQPAAAHAGHKHFNFQAAARHVTYDGKTARIEYVDTANRTVVSVPPAEYETTGFDGSWDNAYYVTPPSQLKRLAVAKRGDTPGTRWYEQAVDTPGARGVNRILWSEKLQAPLSVEFRSADGRVVRKLTLTPATAARHETLPWQTLAGYSRKEYADYLD
>NZ_CP042165.1|WP_039371458.1|1925380_1926520_+|acyltransferase
MSTGPRNARIDMLRGVSIVLVLLHHFNIPYSLRDTSLARVFGWDAVHAVARNGNYGVTMFFVISGYLITSNARRRWGSLGALDVRAFYVSRIARIVPCLLLLLALVNGLAAAGVPIFQNHAPEGIAVSFWLVNLASLTFWMNVLIGAYGWVNYALGVLWSLSVEEVFYLSFPLLCIALRRDARLVAFWVVIAAIGPVYRFTHAGDEGGFLYAYFASFDGIAIGCCTALLAERVTGQRLAAPLVQWLVAGAMATLYLAWPIAQSHVAGVTAMALGTAVLLIGAHVNGERVPGRLLAPLGRAGKLSYELYLFHLIVLGGLRTFWPPSATHGDTKLLLLIAYLALSAALSAAIARGYATPLDRFVKRIASRPSARVPDGARF
>NZ_CP042165.1|WP_046544080.1|1941629_1944536_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein
MNKTYALIWNQAQGCWSAVGETARRRAKPGSTKRVAAALSLLGVVSLPAFALPSGENITAGKADILRDADGKSMRIDQHTDKLITNWNDFNIAGGERVSFYQPGKHSIALNRVVGNNGSQIQGQLEANGKVFLVNPNGVLFGSGAQINVGGLVASTQNIADADFLAGNYRFSGNSTASIVNDGRITAADGGSVALLGARVSNNGVIQAKMGRVALGAGNTFKVNFDGSDLLSLQVEGGAVDAQANNGGLLKADGGEVLMTAQAAGNLLNAVVNNTGAIEAKGLASHAGKITLDGGTVLVGGKLDASAAEAGAPAGSILTRGEQVRVVRGTTVDTRAGNTAGTWTIEAANAGVAKNNAYSLYPAGVSIDADTLSNNLGTTNVALTNTQGDLTVAGPVAWNSDRALTLTSQKGNVDLQQTLSASANASLNVNAADKIRINDAVKLTGRNAHLELNSKNGHTLTNDAAVTLSGDNASFRSNGEDYKVLHTIADLRNVDANLGGRYVIGNTIDGANANFVSIGGATGNAFTGIFDGLGNTISRLAITNPGHHVVGLFGINRGRIANLELKGLSATGSAPRRTLLIGALAGDNFGTISNVTATDVTVSAAGRAYVGGLVGANRGGTIERARVSGRVDGDRETVAIGSLAGANLTLAQKNAPVARIADSHADVHVTTARGTAGGLVGINSGIVETSSSAGSVTMTGDTALIGGLVGHNEANGVVRNTSSTTTITAGNDVVAGGLVGLNAGLLAHSKAGGSIRVGENSVAGGAVGTNHGDVSASRASGMVTASIAGMVGGFVGNNLGVIDTSSATGNVEAGHASLAGGFAGSSRYVIRRASATGDVSAGDGSQVGGLVGQLSGLLDASTAAGAVSGGNVSLVGGLVGNNGGRIRTSSSSGTVSGGYTAKLGGLAGSNFGTVERSSTTSRIAYRSELAQRYGALAGINYGQLIGNTASGNGPDVPLVGFNAGRLQD
>NZ_CP042165.1|WP_046197026.1|1944689_1947740_+|filamentous-hemagglutinin-N-terminal-domain-containing-protein
MNKTYALVWNPLHGRWIAVGETARRRAKPGSAKRVAAALSLLGIVSLPAFALPSGENITAGKADILRDADGKTMSINQHTDKLITNWKEFDIAGGERVTFYQPGKQSIALNRVVGNNGSQIQGQLDANGKVFLVNPNGVLFGSGAQINVGGLVASTQNIADADFLAGNYRFSGNSTASIVNDGRITAADGGGVALLGARVSNNGVIQAKMGRVALGAGNTFKVNFDGSDLLSLQVEGGAVDAQANNGGLLKADGGEVLMTARAAGDLLNAVVNNTGTIEAKGLASRAGKITLDGGTVLVGGKLDASAAEAGAPAGSIVTRGEQVRVARGTTVDTRAGNTAGTWAIEAANAGVANNNADTLYPAGASIDGDTLSNNLGTTNVALTNTQGDLTVGGPVAWNSDRSLTLTSQKGNVDLQQAVSSASANASLNVNAADKIRINDTIKLTGRNAHLELNSKNGHTLNKDVVVTLSGDNASFRSNGEDYKVLHNMADLRNVDANLGGRYVIGNAIDGANTSFRSIGGSGTFTGVFDGLGNTISRLSITGTGPNIGLFGQSTGYLANLTLDSLTVDGTSAARATFVGGLVGDNLGRIENVNAKNTSVSYNGRNMVMMGGLVGRNLGTIDRANFAGRVSGSANTLSVGGLASVNGGTIADSTASADVTLSGSSGSPFQGSYSREVQSIGGFVGTNNGEIVRSSSRGRVSGRDDTSTGGFVGINFGTIRNASANATVTAGKGSYVGGFAGKIRDDGTIANASASGPVWANGALAIGGFVGDNAGGTLDGVQSDGDVTDLASGHVGGLAGRNGGTIRHAQARSTVTTGRNSHAGGLVGTNDGAVSNSSATGRVSAGEASDAGGLVGLNTGELDTVTATGNVTAGNGSRVGGLVGTNQGNRAIVRHAATTGNVGANNSTVGGLVGLNDQGAVIDDASSTGTIAGTFSTLGGLVGENAGTIRASTSSSRIDPASTIYGGRSWGTLVGYNNRSGNIEASSVEGAAQPYYMVGLSIGKINGQWYYGPVDR
>NZ_CP042165.1|WP_039369787.1|1948171_1948813_-|hypothetical-protein
MATLAFPISAAAAIDMVPKDVTLKETVTSVEVINNGDRAEYVSVSLSRLLNPGVPFENERLEPVGEIDQPSIYASPFRMSLAPGQTKTIAIKVLRPVDTETVYRLDVKPVIKVLGTGHAKSSASVVANLAFSGIVRQMPSKTRAALAVACEASGARLTATGNVHYRVEGAKADGQRLDDFNVYPGVPLPVPGRIVDIPGHSVCGAAAAKSPLP
>NZ_CP042165.1|WP_046197024.1|1948937_1949444_-|hypothetical-protein
MLPAVLLAEPVKLTGKTTSRVTAHVSRPNNLFVTDDKGGWFDQGLQMQQLGGWDTPYEVQARLKIVSTSGVFQVRLDSPLTITHQSKPTLVFRTPTVKLAPEGGVPKPLLVGQGTEFQNPAASGARDDSVGYYNLDIAAYPPTGNFKDNTGTYKGVLSMTFEPVIKAP
>NZ_CP042165.1|WP_135370735.1|1949491_1950511_-|hypothetical-protein
MNRISRERGSFGRWCKVVLLFFLAMSVGRAYGYILVLDNLSNGYSGCSWVDNGNGTSTVSVSIDYKSVVGHLGGRLFTSRGILIYTYNRNGELNPSANVARAMNINGKPYESAFVGTGYVMYKNSNYPGPSTGDWTNGSPFIANVVATVSNSVIADWPAIGIRAGNYTDGDDVGEVTGVAYIRFGENRGVCNIVVNPEVPPPPVEITMNMTAPDWNLGDLGQGDSKKTFSDTANQLCFTYPGSVVTGVRFIVNAKNVNGEVANRYRLKNVDDASQFVPYSIKLDGGGSTLSLPNSSNMAMRFASSGKTCFVPTFETTVDSNVKEGDYVDVLIFTVVTPS
>NZ_CP042165.1|WP_052760189.1|1950590_1951067_-|hypothetical-protein
MNRALCRALGALLLLWSSGSFAAGILKLSRTELTLAPDKPANELWVENVGDTPLYLDITQQRVLNPGHLPEQLVPVEEVSQPTLLVLPTRLALSPGQKYRMALKELSMPDESQVWRVTFRPREHIVVDADRDGDTTAPLFVSVGYGVVIYQSLAGAVR
>NZ_CP042165.1|WP_148668959.1|1951066_1951753_-|pilus-assembly-protein
MNFNAKHWALALVALACATVRPALAEGELMVMPAATRVYATHDQKVTVRNMGDAPLFLSITLQKIMNPGVTPEKKVDLGQLDNPGMLASPDKLTLGPGQSRQIELKSLTDPAQEEVYRLYVVPIRSLKVEDAPADKITAPMSVAIGYGVLVRHLPPPGKLNVAWTHRCEDGGITLESTGNVRTLFSNASYDGVKQPQTIAVFPGTPQHFATKRMTLSVQDEPKTLQCP
>NZ_CP042165.1|WP_039369805.1|1951757_1953917_-|fimbrial-protein
MDDSARYVATFNGKTLPGFVRYSATESVLEFDAAKYAANGVSPDDVDTIRNVVSKIDYKRCSKGCDIEVDGYYVTIDKLRRSISIRNSREDYFAPETTFGLVNNQSVDFRASSNGYRAANLNGATWVGLPSRSFGYVSWYANRTQTRGTSYGSQGVSSYYLQKNFAGTYLRAGKQNSIDYASGSVSTLLSPSFDQFVTFGSQSNLQVNRDAGSLVLYATAEGNYEFYRNGRLIMKRPAALGRNEISFADLPGGYYPVQVRLVDRNGNLVSQEIREINNVNFGAGGGNAWHFTVGKEMSDRGGFLMEGAMSRNFRQFYMNASTLVGRGGDWAAEVNVTRPTKIGDVDVTPTLGVLAGERKAGGYVSLAASSEALGSLSASRYLNNDVSRFYAGTSSTSVTYSRMVRKATVGYNYQQSGFGATHQAEVRWNYRPNGLWATFALGVQKGSFSRTSGGYGVYFNMTMQLDKVQASFSAARSGGQTQLSGDYRKDFQDGFGTTTLGVTGNRINSDYGINVYGSRSGTRGDASLNLGYNGDASNVDFNYRGMVAASKDGVAFGRYSNGGSAMLLRTPKLDGMRYGFNVEGSPVGGGSTYAVPLNTYTDVAFARVYSNSDKLDMNIEVPANIVRAHPGQVYAAQAKVDINMVYSGFLKDTEGKPISGKVVETGDVVHRNGLFSIVSKTMLSQVTVDGDGHRYTCSLKDASGNDFRCELPGLKESKE
>NZ_CP042165.1|WP_039369777.1|1954166_1954715_-|hypothetical-protein
MKLSKLVLAMGVTTALFGMAHTAQADTVSKKVTLTAQINDGIFVSKPDGSTWYGTEELEANDYTQTKFSKTLPVRVYTKNPDFNISLASPLKLTNGNYEMKNAKVTLGSAAGDSEVKFGAVQKVTQTVSGNGGFDEVHNLKINVDAPTMVGTNSTNGSYSGDLVMVFEPLAAAGGGDTPASK
>NZ_CP042165.1|WP_039369774.1|1955190_1958193_-|hybrid-sensor-histidine-kinase/response-regulator
MPAKLKRLLAHAAAVGRKPFDPGRVRRQQQMLLYGGGCAITAFIVVCAALVVRLDVQDSLERARSTFLQREAEFYANLQTLDRMLAMLGNRTEELWRKGAPPPQDALRAFAADHGRLAASNAGGGTPFFAMAEVTPARPAESYARYLGAALGQVDRGARYPPVPMRAEPIGGYLIALDGPFLGVLGPGVVARARALPPDTDLRALIDRLMPNGAAKQKPDMQGATFMLDRRYDPVVGRTVIRFARRLDDDDGRPFGWLVLNGRFRLDDIMSPQSDDEDVAVLAADGRVVFGRPRDPALIARAMADAGAQSGKHVVVRRIGTRFAIVDSLSDTGLTMAATFSWRSVARATAVGVSVTLGAALFTVAMLWITIVTFDRRALRPAHRRAIRLIESEAFNRTLIHTAPAGLLLLAAADGETMVRNDAALAYEDGASGLPLGKRIWQACRERQRAGTGERRFVMQQELAVERAGHDTTYLAAHIVRTKFRGVAVLLCTLTDVTARRLTENKLREARVAADDANKAKSTFLATMSHEIRTPLNAIVGNLELMERAELPSVERQRLKTIVSSSDALLRVINDVLDLSKAESNQMALEQIPFDLRRVLQDVAAIFRPLAEAKGLTLECDVAAELADGHVGDPTRLRQLVSNLVGNAIKFTEYGGIAIDARRVRGGDGAGEVEIAVRDTGVGIPEDALPTLFDVYMQADASIYRRFGGTGLGLPLCRRIARLMHGELTVESQVGSGSTFVATLPLPAAPAGWRSAEPEPDTALAPQQRTDVQPLRVLVAEDHPASRALLRDQLDALGHDATIVENGVEAMRAYFEHPFDVVLTDLSMPQLDGFALANFLREQGASVPVIAMTAHATDDDRRRCAQVGVAEVVLKPLSIDVLDEALQRHGGQRGVRAEQAQSGAHEQAPAVTGEIRHALREATLRSLGAIEAALSAGNTNALVIELHSMRGGFALAGDSVARDACAQMEATVKSGGAAAFESHWDAFRSAIEHAMERIGQ

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Crispr_ID: NZ_CP042165_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP042165_2

2467201-2467520

Orphan

Consensus_repeat	Method
ATCGGCGGCGCCATCGGCGGCGGCGC	CRISPRCasFinder

4 spacers

The CRISPR arrays of NZ_CP042165_2

>merge|NZ_CP042165|2|2467201-2467520|CRISPRCasFinder
ATCGCCCCCGCTCTCGTCGTCGCCGCGTTGACCGGCGCGACTGCACTGCCGGCCATGGCAGGTGACATGAACAACGCGCTTGGCGGCGCGCTCGGCGGGGTAGCCGGCGCAGCGGTCGGCGGTGCGCTCGGCGGCAGCACGGGCTCGGTGATCGGCGGCGCCATCGGCGGCGGCGCGGGTGGCGCGGTGACGTCGAACCGTCACGAGCGCACCGGCGCGATCATCGGCGGCGCCCTCGGCGGCGGCGCAGGTACCGCGGCAGGCAACGCGATGGGCGGCCGCACGGGCGGCCTGCTGGGTGCGGCTGTCGGCGGCGGCGC

>NZ_CP042165|2|2|2467201-2467520|CRISPRCasFinder
ATCGCCCCCGCTCTCGTCGTCGCCGC	GTTGACCGGCGCGACTGCACTGCCGGCCATGGCAGGTGACATGAACAACGCG
CTTGGCGGCGCGCTCGGCGGGGTAGC	CGGCGCAGCGGTCGGCGGTGCGCTCGGCGGCAGCACGGGCTCGGTG
ATCGGCGGCGCCATCGGCGGCGGCGC	GGGTGGCGCGGTGACGTCGAACCGTCACGAG
CGCACCGGCGCGATCATCGGCGGCGC	CCTCGGCGGCGGCGCAGGTACCGCGGCAGGCAACGCGATGGGCGGCCGCACGGGCGGCCTG
CTGGGTGCGGCTGTCGGCGGCGGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP042165.1\|WP_039349797.1\|2458445_2459753_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187579
NZ_CP042165.1\|WP_011353812.1\|2457823_2458357_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224427
NZ_CP042165.1\|WP_039349792.1\|2456460_2457663_-\|trans-2-enoyl-CoA-reductase-family-protein	unknown	unknown	gnl\|CDD\|237460
NZ_CP042165.1\|WP_039349886.1\|2474070_2474682_+\|trimeric-intracellular-cation-channel-family-protein	unknown	unknown	gnl\|CDD\|225415
NZ_CP042165.1\|WP_039349861.1\|2465133_2465553_+\|HIT-family-protein	unknown	unknown	gnl\|CDD\|238608
NZ_CP042165.1\|WP_039349892.1\|2475652_2476741_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223682
NZ_CP042165.1\|WP_039349880.1\|2470907_2471702_-\|phosphotransferase	unknown	unknown	gnl\|CDD\|226100
NZ_CP042165.1\|WP_039349802.1\|2460320_2461193_+\|DUF393-domain-containing-protein	unknown	unknown	gnl\|CDD\|367833
NZ_CP042165.1\|WP_039349864.1\|2466150_2466810_+\|isoprenylcysteine-carboxylmethyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224931
NZ_CP042165.1\|WP_039349895.1\|2476756_2477671_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|226928
NZ_CP042165.1\|WP_039349878.1\|2469528_2469903_-\|heavy-metal-responsive-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133398
NZ_CP042165.1\|WP_039349799.1\|2459749_2460220_+\|DUF2269-domain-containing-protein	unknown	unknown	gnl\|CDD\|370783
NZ_CP042165.1\|WP_039349879.1\|2470002_2470830_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223377
NZ_CP042165.1\|WP_039349883.1\|2471941_2474062_+\|PBP1A-family-penicillin-binding-protein	unknown	unknown	gnl\|CDD\|273955
NZ_CP042165.1\|WP_039349897.1\|2477667_2478759_-\|hemin-degrading-factor	unknown	unknown	gnl\|CDD\|226243
NZ_CP042165.1\|WP_039349838.1\|2461189_2462689_+\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|273800
NZ_CP042165.1\|WP_039349841.1\|2462761_2463385_+\|glutathione-S-transferase	unknown	unknown	gnl\|CDD\|198289
NZ_CP042165.1\|WP_039349877.1\|2468514_2469351_+\|(S)-ureidoglycine-aminohydrolase	unknown	unknown	gnl\|CDD\|183011
NZ_CP042165.1\|WP_039349889.1\|2474811_2475633_-\|heme-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|184132
NZ_CP042165.1\|WP_039349844.1\|2463477_2464878_-\|serine-hydrolase	unknown	unknown	gnl\|CDD\|224594

Protein	Function_ID	Function_description	E-value
NZ_CP042165.1\|WP_039349797.1\|2458445_2459753_+\|SDR-family-oxidoreductase	gnl\|CDD\|187579	cd05271, NDUFA9_like_SDR_a, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, subunit 9, 39 kDa, (NDUFA9) -like, atypical (a) SDRs. This subgroup of extended SDR-like proteins are atypical SDRs. They have a glycine-rich NAD(P)-binding motif similar to the typical SDRs, GXXGXXG, and have the YXXXK active site motif (though not the other residues of the SDR tetrad). Members identified include NDUFA9 (mitochondrial) and putative nucleoside-diphosphate-sugar epimerase. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.52177e-54
NZ_CP042165.1\|WP_011353812.1\|2457823_2458357_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|224427	COG1510, COG1510, Predicted transcriptional regulators [Transcription].	6.42957e-41
NZ_CP042165.1\|WP_039349792.1\|2456460_2457663_-\|trans-2-enoyl-CoA-reductase-family-protein	gnl\|CDD\|237460	PRK13656, PRK13656, enoyl-[acyl-carrier-protein] reductase FabV.	0
NZ_CP042165.1\|WP_039349886.1\|2474070_2474682_+\|trimeric-intracellular-cation-channel-family-protein	gnl\|CDD\|225415	COG2860, COG2860, Predicted membrane protein [Function unknown].	1.65647e-63
NZ_CP042165.1\|WP_039349861.1\|2465133_2465553_+\|HIT-family-protein	gnl\|CDD\|238608	cd01277, HINT_subgroup, HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides. This subgroup includes members from all three forms of cellular life. Although the biochemical function has not been characterised for many of the members of this subgroup, the proteins from Yeast have been shown to be involved in secretion, peroxisome formation and gene expression.	2.11415e-47
NZ_CP042165.1\|WP_039349892.1\|2475652_2476741_-\|iron-ABC-transporter-permease	gnl\|CDD\|223682	COG0609, FepD, ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism].	7.01012e-78
NZ_CP042165.1\|WP_039349880.1\|2470907_2471702_-\|phosphotransferase	gnl\|CDD\|226100	COG3570, StrB, Streptomycin 6-kinase [Defense mechanisms].	1.12675e-81
NZ_CP042165.1\|WP_039349802.1\|2460320_2461193_+\|DUF393-domain-containing-protein	gnl\|CDD\|367833	pfam04134, DUF393, Protein of unknown function, DUF393. Members of this family have two highly conserved cysteine residues near their N-terminus. The function of these proteins is unknown.	5.13158e-19
NZ_CP042165.1\|WP_039349864.1\|2466150_2466810_+\|isoprenylcysteine-carboxylmethyltransferase-family-protein	gnl\|CDD\|224931	COG2020, STE14, Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones].	6.19655e-26
NZ_CP042165.1\|WP_039349895.1\|2476756_2477671_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|226928	COG4558, ChuT, ABC-type hemin transport system, periplasmic component [Inorganic ion transport and metabolism].	4.03864e-78
NZ_CP042165.1\|WP_039349878.1\|2469528_2469903_-\|heavy-metal-responsive-transcriptional-regulator	gnl\|CDD\|133398	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators. Helix-turn-helix (HTH) heavy metal resistance transcription regulators (HMRTR): MerR1 (mercury), CueR (copper), CadR (cadmium), PbrR (lead), ZntR (zinc), and other related proteins. These transcription regulators mediate responses to heavy metal stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	6.478e-42
NZ_CP042165.1\|WP_039349799.1\|2459749_2460220_+\|DUF2269-domain-containing-protein	gnl\|CDD\|370783	pfam10027, DUF2269, Predicted integral membrane protein (DUF2269). Members of this family of bacterial hypothetical integral membrane proteins have no known function.	1.82774e-57
NZ_CP042165.1\|WP_039349879.1\|2470002_2470830_+\|SDR-family-oxidoreductase	gnl\|CDD\|223377	COG0300, DltE, Short-chain dehydrogenases of various substrate specificities [General function prediction only].	4.46736e-104
NZ_CP042165.1\|WP_039349883.1\|2471941_2474062_+\|PBP1A-family-penicillin-binding-protein	gnl\|CDD\|273955	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NZ_CP042165.1\|WP_039349897.1\|2477667_2478759_-\|hemin-degrading-factor	gnl\|CDD\|226243	COG3720, HemS, Putative heme degradation protein [Inorganic ion transport and metabolism].	4.23664e-140
NZ_CP042165.1\|WP_039349838.1\|2461189_2462689_+\|TIGR01777-family-protein	gnl\|CDD\|273800	TIGR01777, Hypothetical_UPF0105_protein_Rv2216/MT2273/Mb2239., TIGR01777 family protein. This model represents a clade of proteins of unknown function including the E. coli yfcH protein. [Hypothetical proteins, Conserved].	9.45197e-109
NZ_CP042165.1\|WP_039349841.1\|2462761_2463385_+\|glutathione-S-transferase	gnl\|CDD\|198289	cd03180, GST_C_2, C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases. Glutathione S-transferase (GST) C-terminal domain family, unknown subfamily 2; composed of uncharacterized bacterial proteins, with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress. GSTs also show GSH peroxidase activity and are involved in the synthesis of prostaglandins and leukotrienes. The GST fold contains an N-terminal thioredoxin-fold domain and a C-terminal alpha helical domain, with an active site located in a cleft between the two domains. GSH binds to the N-terminal domain while the hydrophobic substrate occupies a pocket in the C-terminal domain.	8.51979e-48
NZ_CP042165.1\|WP_039349877.1\|2468514_2469351_+\|(S)-ureidoglycine-aminohydrolase	gnl\|CDD\|183011	PRK11171, PRK11171, (S)-ureidoglycine aminohydrolase.	0
NZ_CP042165.1\|WP_039349889.1\|2474811_2475633_-\|heme-ABC-transporter-ATP-binding-protein	gnl\|CDD\|184132	PRK13547, hmuV, heme ABC transporter ATP-binding protein.	2.60391e-168
NZ_CP042165.1\|WP_039349844.1\|2463477_2464878_-\|serine-hydrolase	gnl\|CDD\|224594	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms].	7.64372e-40

>NZ_CP042165.1|WP_039349864.1|2466150_2466810_+|isoprenylcysteine-carboxylmethyltransferase-family-protein
MKVTSRAAVASCIATLVYLGLAVLGSGGFEAFFSHPQLTVVVVATLAMAVAALFTEGNLSSGERENRDNRWVLAAFGVSGFLLAYLPALTDRLDFWTFGGDAVRWIGVVLYIVGGVLRIWPVFVLGKRFSGLVAIQPGHTLVTDGIYSRIRNPSYLGLVVNSVGWAFTFRSGVGLLLVVLTMVPLVARIRSEEALLRAQFGAEYDAYCARTWRLLPGVY
>NZ_CP042165.1|WP_039349861.1|2465133_2465553_+|HIT-family-protein
MSYDNNNPFAKILRGELSCVKVAEDDATLAIMDLMPQADGHVLVIPKEPAAQIFELSGDAAAAGIRMTQRVAAAVRAALEPDGVFIGQFNGAAAGQTVPHVHFHVIPRWEGAELRMHAREIADAATLEALAQRIRARFV
>NZ_CP042165.1|WP_039349844.1|2463477_2464878_-|serine-hydrolase
MTIPFKKLILRGVALAVVVAVGYTGYMLSRLAPIATGYAAKALCSGVYVSGRPAASVIDVDIMAGVHPLLKLVHPSIDPDHHRATATFAGFAEREADFRPGLGCTLALGPSPGALPAALPPLPDPPSTQPAPVTPPAGIDAQKLQTALDRAFDEPDPARPRRTRAVVVMWRGQVIAERYAPGFTADTPLPGWSMTKTVTAALVGTLVAQHKLSPDASALLPEWRGSGDPRAAITLDALLRMTSGLQFNEDYDDPLSDVALMLYAQPDTARFASEKPLAATPGTRWSYSSGTSAILARVMREALGSSDGDYLALPRRALFAPLGMRSAVFEPDASGTLVSPSYMYASARDWARFGQLLLQDGVWDGQRLLPEGWVRYLTRTTPQSERQEYGAQLWVKVPEPFNDRDPHAVAMPADAFHAVGHEGQFVSVVPSRQLVVVRLGLSRPESAWNHEAFLARVLDAVPAPGA
>NZ_CP042165.1|WP_039349841.1|2462761_2463385_+|glutathione-S-transferase
MLHILGKIPSINVRKVLWLCTELNLPFEQEDWGAGFRTTNDPAYLALNPNGLVPVIKDDDFVLWESNTIIRYLANRYGGDALYPAEPQARARVDQWIDWQGADLNRSWVGAFLGLVRKSPDHQDPAGIAQSIAGWTKHMQVLNTQLEATGAYVAGNGFTLADIPIGLSVNRWFGTPFEHPDFPAVSRYVERLATREGFQKYAGSANP
>NZ_CP042165.1|WP_039349838.1|2461189_2462689_+|TIGR01777-family-protein
MNTLPAYDWALNLLIVQGAMGAFDTLYHHELTQDLPHSPRAQLELGIHAVRSVLYGLVFASIANVAFHGAWVAAIAAVVVVEVVLTLWDFVVEDQSRKLPATERVLHTLLAVNGGALFGMIAMQLAAWAHEPTALQALDLGWRGWVLSLFAVGVTVSGIRDGIAACRIARRAPVANPFAGQPPGNVLVTGGTGFIGETLVNHLLDAGHTVTLLARDPLRAAYTFHGRVRSVTSVGQLQPHERFDTVINLAGAPVLGARWSKRRRAVLLASRVGVTESLMRWVETAEVKPRTWIQASAIGYYGVRPADERLDESSSAGAGFMSELCRQWEQSARPLERHGVRSVVLRLGVVFGPGGALRPMLLPHYVGMGGRFGDGTQVMSWIHRDDVLRIIARAMANPGMHGVYNAVAPAPLTQREFVQVVSKVLRRPAWLHVPAAPLRIAMGEMAELLLDGQRVMPARLHQDGFMFRFPTAEHALRDLTNRPHADFPCMACRLPRGRV
>NZ_CP042165.1|WP_039349802.1|2460320_2461193_+|DUF393-domain-containing-protein
MRSSELVLYFDGRCPLCVAEIKRLGARDARHRLAFVDIAKPGFDPAPLGVDLPALNRELHARLPDGRMLTGVDSILAAQALTGRRTLVRLLRVPAVRGVLALLYRRFARNRHAVSRWLGYRTEAPCDAAACGSGSERAAEPTPDRPAGGAARRLVVTWMYVAATAHVLVGMAVPWVAGAPWLDAYHRVIELHFWAGAAPDAARAQQVWWMSLMGATVQCASVWMLALVHLGNRLRKREVWGWLLAGLLIWAPQDMLFSLQAHVSGHVAIDAAALVAMVPPLVWLWRRDAV
>NZ_CP042165.1|WP_039349799.1|2459749_2460220_+|DUF2269-domain-containing-protein
MNTYLVIKALHILSSVLLVGTGFGTAFYLFFANRTRSVPAIAAVSRLVVRADWWFTTPAVIFQPASGLWLAHTAGWPWDTPWLVASIVLYAIAGVCWLPVVWLQLELASMAKLAHANGNAALPERYWRYAKRWELLGYPAFFAMLTVYFLMVLKPM
>NZ_CP042165.1|WP_039349797.1|2458445_2459753_+|SDR-family-oxidoreductase
MDTVLPSTRPHGRTRAHSMTVLVCGANGFIGRALCAQLEAGGHRVLRGVRHATGLCDVEIDFAQDIDPDAWLARLEGVDVVINAVGILADQRGATLDAVHRAAPCALFTACCRAGVRRVIQISALGVERGNTRYFASKCAADRFLKTLPIDFRIVRPALVYGTDGASARFFRMLASLPVQVLPAGGHQRLRPVHVDDLAEVVARCVDAPAVGRAVIDVVGADEVEYREMLARYRAALGFPPAARIGLPGPLAGMAAALLGTLPGAIFTRDTWTMLRGGNTGDPAAATAMLGRPPRGIDGFIGAEAAALRRDALAMWRRPLLRGALAIVWIWTAIASAFIHPLHASLALLAPAHLTGLPALIALYAASALDFSFGIATVVAPSRRLWGAQAALIVAYSAVIAVTMPGLLAEPFGPVLKNVPILAILLILFSEEEQA
>NZ_CP042165.1|WP_011353812.1|2457823_2458357_+|MarR-family-transcriptional-regulator
MELTPIAERFILHWGEMGSRWGVNRTVSQIHALLYLAGRPIAADEIAETLNVARSNVSTSLKELQAWRLAKVVHVLGDRRDHFETSTDIWELFKLIVEGRRQREIEPTLTVLRDCLTNPEIANESRETEQRIRDTLQFVETLTTWSDEMLRLKPDTLMKALGIGAKISQTVRRKPSK
>NZ_CP042165.1|WP_039349792.1|2456460_2457663_-|trans-2-enoyl-CoA-reductase-family-protein
MIIKPRVRGFICVTTHPVGCEANVKEQIDYVTSHGPIANGPKKVLVIGASTGYGLAARISAAFGSGADTLGVFFERAGSETKPGTAGWYNSAAFEKFAAEKGRYARSINGDAFSDKVKQVTIDTIKQDLGKVDLVVYSLAAPRRTHPKTGETISSTLKPIGKTVTFRGLDTDKEVIRDVTLEPATQEEIDGTVAVMGGEDWQMWIDALDEAGVLADGAKTTAFTYLGEQITHDIYWNGSIGEAKKDLDKKVLSIRDKLAAHGGDARVSVLKAVVTQASSAIPMMPLYLSLLFKTMKENGTHEGCIEQVYGLFKDSLYGATPHVDAEGRLRADYKELDPQVQAKVVAQWNHVTNENLYELTDFTGYKTEFLRLFGFEIAGVDYDADVNPDVKIPGIIDTTV
>NZ_CP042165.1|WP_039349877.1|2468514_2469351_+|(S)-ureidoglycine-aminohydrolase
MSKTTYYAPHGGHPPQTDLLTDRAMFTEAYAVIPKGVMRDIVTSWLPFWTNTRLWVIARPLSGFAETFSQYIVEVNPGGGSDKPEQDKNAEAVLFVVEGEAELTLQGTKHVLKPGGYAFIPPGADWTLHNVSDAAVRFHWVRKHYQAVDGIPLPEAFVTNEQDVEPIPMPGTNGAWVTTRFVDMSDMRHDMHVNIVTFEPGGVIPFAETHVMEHGLYVLEGKAVYRLNQDWVEVEAGDFMWLRAFCPQACYSGGPGRFRYLLYKDVNRHMNLLLNPAR
>NZ_CP042165.1|WP_039349878.1|2469528_2469903_-|heavy-metal-responsive-transcriptional-regulator
MRIGELCKRAGVSHDTVRYYERMGLLDKATRPHATNTYKHYSERSLQRIRLIIHAKALGFTLTEIGDVIHVWDSPTFGVAQKVACLQAKLTEIDEKSRALVMLRAGLLNALAKVGSDCVEGHIA
>NZ_CP042165.1|WP_039349879.1|2470002_2470830_+|SDR-family-oxidoreductase
MRDRFDFHGKTALVTGASSGIGRAFAYALAKRGARLLLVARSRDKLHDLAAELRRDYACDADFLTVDLSTADAVHTIDCHLKVTGKVVDVLVNNAGFAAYGRFETIPWTRQRDEVLVNCMAAIELTHLLLPGMQARSAGAVINVASTAAFQPDPYMAVYGATKAFLLSFSEAVWAENRHRGIRVVALCPGATQTAFFDVVGAQEAAVGTPMPVASVVEDALWALDRNRSHRIVGTRNRLLANLQRLLSRETSARLVEKILRPRGGQDPVTRETNA
>NZ_CP042165.1|WP_039349880.1|2470907_2471702_-|phosphotransferase
MFDRYLGLWGLVPDGGPLLTASGGLLPVVWQSRPAMLKVATCDEERRGNALMTWWNGQGAAQVWLHDGDAILLERAQPEPTLAGFSASGHDDDAMRIACDVVARLHAHRASEPPSVVALHAWFQALLSDASASVVLHRSATVARQLLAGPPVDEVVLHGDIHHGNILHFGDRGWRAIDPKGLRGDRAFDYANLFCNPSHDVAVDPVRFAQRVTLVASTAQLDRRRLLQWILAWSGLSAVWLIEDELLPDTRLQVATLAAAALGL
>NZ_CP042165.1|WP_039349883.1|2471941_2474062_+|PBP1A-family-penicillin-binding-protein
MTDHTAAPPPPPASPPRRRRVWRTLAGALLGLTVACAGIGAWTIQRIWTQLPSVEHLAVYRPALPLRIFSRDGDLLAEYGVERREFVPLERIPPLMRQALLAAEDAKFYQHGAVDFGGLARATFANVVTGQPGQGGSTITMQVARNFYLTRDKVLSRKLAEILMAAKLEREYSKDKLLELYMNEIYLGERTYGFAAAANVYFGKPLDALSAGEAAVLAGLPKAPSAFNPVVNPARATARRNYVLGRMHALGQLDDATYHAAVDAPIALATTPPPGIIAAPYVAERARRMMVERFHDDAYTLGLDVTTTISMRDQRAAESSLARTLSRQTRAKRDARNGLEGALVSLDAATGDMLALVGGADFNRNVFDHALQAYRQPGSSFKPFVYSAALEKGYFPGVLVDDTQRTLTHEETGARPWRPRNFANNYEGFIPVRRGLMRSKNLVAVSLMQATDARYVQQHAVHFGFDAQRNPASLPLALGAGAVTPLELASAYSVFANGGTRMEPRLILSVKQRHGGAMYEATAPAGERVVSARNAFVMDSMLRDVVKSGTARGALALRRDDAAGKTGTSNGSKDVWFAGYSSGIVAVAWLGYDTPRPMGRATGATLALPVWLDYMKTAVDGRTPVEATPPQDVALVDGDFVYAEYTRGTCTADVPSYIRSRFACGGAAAAGASDAPGNDGKPAESTPAAVDAAERERVLDLFRTDD
>NZ_CP042165.1|WP_039349886.1|2474070_2474682_+|trimeric-intracellular-cation-channel-family-protein
MHTLYLIAIVAEAMSGALMGMRRGMDRFGLALVGAVTALGGGTVRDVLLGHYPLGWIAHPEYLVITLVAATVASWVARHVARMKTLFVTVDAIGLAAFTIIGCDIGASTGSAPIIVVLAGAITGVCGGMLRDLLCNEMPLILREELYACVAFVTGGLYVGMQHLGVDAGIATVAALAAGFSMRMLAVRLGWKMRTFGAADLEH
>NZ_CP042165.1|WP_039349889.1|2474811_2475633_-|heme-ABC-transporter-ATP-binding-protein
MLTAHHLDVARRHHAILRDLSLSIVPGRVTALLGRNGAGKSTLLKTFAGELTGNVAPNGVRVTGDITLNGEPLARIDAPRLACLRAVLPQAAQPAFPFSVDEIVLLGRYPHARRSGATSHRDRDIAWCALERAGADGLVGRDVTTLSGGELARVQFARVLAQLWPDDEATESGPRYLLLDEPTAALDLSHQHRLLETVRAVAREWQLGVLAIVHDPNLAARHADTIALLADGTIVAHGTPRDVMTPSHIAQCYGFAVKMVETGDGAPPVMVPA
>NZ_CP042165.1|WP_039349892.1|2475652_2476741_-|iron-ABC-transporter-permease
MPAHASPFPASSSASRSGAARIGTSRRFAPFALAALACLVCAMSVVALCVGAYRIPLAEAWAALTGDAAAQQARAVLFDIRAPRVALALLVGGGFGATGAAMQALFRNPLADPGLVGVSSGAALGATTMIVLGPALFAAQVSAAALPAAAFAGALAVAALVYRLAASRGRLALPLLLLAGIAINALVGAAIGLLTFIADDAQLRSLTFWSLGSLGGAQWSALAAVAPCVAIGGALLARERDALNALQLGETEALHLGVPVQRLKRRVLVAVALAVGALVSCSGIIGFIGLVAPHCVRLVCGPDQRVVLPGAALFGALLTLAADLAARTVAAPAEVPLGVLTALLGAPFFLALLWKSRGALGG
>NZ_CP042165.1|WP_039349895.1|2476756_2477671_-|ABC-transporter-substrate-binding-protein
MSARPFDPRRRALLASAAAGALAGALPGSVLAQGAQATPKRVVVIGGALAETAFALGGAETPRYRLVGADTTCTYPDAAKRLPKVGYQRALSAEGLLSLRPDLVLASAEAGPPTAIAQVKNAGVAVTTFDERHDVESVRAKITGVAQALDVRDAGAALLQRFDRDWQAARDAVAARARGDAPPRVLFVLNHTGNQALVAGQRTAADAMIRYAGARNAMQGFDHYKPLTTEALAAAAPDVVLISDEGLAAVGGRAALLATPGFGATPAGRAQRVVSLDALFLLGFGPRLPLAVTTLHRRLSDALA
>NZ_CP042165.1|WP_039349897.1|2477667_2478759_-|hemin-degrading-factor
MMQSALPGQPATPARAAAALRDAFIKLKTERQLRNRDVAQALGVSEGEALAAFVGEHVVRLDARFPAMFEEMPRLGRVMALTRNDTAVHEKDGEYAQMSHDGPVGLALGDIDLRIFYRHWVSAFAVRDETAHGPLKSLQFFDAQGHAIHKVYLRAHSDHAAYDAFVERWRAPSQEPGLEVAPAAPKTPERADTEIDVAGFRAAWDAMTDTHQFFGITQRFGVSRMQALRLADPQYAYPVETAHALRHVLQHAAESGQPIMVFVGNAGMIQIHTGPVANVREVGAWINVLDPGFNLHVREDLIAAAWVVKKPTSDGIVTSLELFDRQGDHVALLFGERKPGQVERDDWRALVATLPAAARGGAR

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP042165_2	2.3\|2467377\|31\|NZ_CP042165\|CRISPRCasFinder	2467377-2467407	31	NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	37563-37593	6	0.806
NZ_CP042165_2	2.3\|2467377\|31\|NZ_CP042165\|CRISPRCasFinder	2467377-2467407	31	NC_016626	Burkholderia sp. YI23 plasmid byi_1p, complete sequence	1327605-1327635	6	0.806

1. spacer 2.3|2467377|31|NZ_CP042165|CRISPRCasFinder matches to NZ_AP014579 (Burkholderia sp. RPE67 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.806

gggtggcgcggtgacgtcgaaccgtcacgag	CRISPR spacer
gggtggcgcggtcacgtcgaatcgcagggag	Protospacer
************ ********.**. . ***

2. spacer 2.3|2467377|31|NZ_CP042165|CRISPRCasFinder matches to NC_016626 (Burkholderia sp. YI23 plasmid byi_1p, complete sequence) position: , mismatch: 6, identity: 0.806

gggtggcgcggtgacgtcgaaccgtcacgag	CRISPR spacer
gggtggcgcggtcacgtcgaatcgcagggag	Protospacer
************ ********.**. . ***

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP042166

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 774

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039364532.1\|0_774_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.2e-81	56.5

DBSCAN-SWA_2

11449 : 11800

Leptospira_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039370807.1\|11449_11800_-	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	1.3e-16	38.5

DBSCAN-SWA_3

33580 : 34573

Burkholderia_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007182917.1\|33580_34573_+\|transposase	IS5-like element ISBmu23 family transposase	E5E3P6	Burkholderia_phage	1.3e-186	100.0

DBSCAN-SWA_4

38060 : 42277

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_082139458.1\|38060_38813_-	hypothetical protein	A0A2H4J162	uncultured_Caudovirales_phage	8.4e-10	30.6
WP_076841459.1\|38890_39403_-	hypothetical protein	NA	NA	NA	NA
WP_082139457.1\|39719_40826_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_039353638.1\|40879_42277_+	MFS transporter	A0A0M3UL24	Mycobacterium_phage	6.8e-21	28.6

DBSCAN-SWA_5

46709 : 52797

uncultured_virus(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080001177.1\|46709_47978_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	3.5e-40	43.9
WP_144610378.1\|47919_49557_-	pyridoxal-phosphate dependent enzyme	NA	NA	NA	NA
WP_039353627.1\|49594_51313_-	hypothetical protein	M1ICZ5	Pelagibacter_phage	1.7e-45	29.1
WP_039353624.1\|51309_52797_-	SPASM domain-containing protein	A0A1B2IA90	Erwinia_phage	3.4e-10	25.6

DBSCAN-SWA_6

64652 : 65447

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046196575.1\|64652_65447_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	3.9e-13	29.9

DBSCAN-SWA_7

89111 : 91111

Micromonas_sp._RCC1109_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039353545.1\|89111_90146_-	4-hydroxy-2-oxovalerate aldolase	E5EQ69	Micromonas_sp._RCC1109_virus	6.5e-45	32.0
WP_039353542.1\|90166_91111_-	acetaldehyde dehydrogenase (acetylating)	E5EQ71	Micromonas_sp._RCC1109_virus	2.1e-34	34.3

DBSCAN-SWA_8

96509 : 97922

Puniceispirillum_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046196578.1\|96509_97922_-	Rieske 2Fe-2S domain-containing protein	S4S2K9	Puniceispirillum_phage	6.7e-08	39.3

DBSCAN-SWA_9

101601 : 109674

Escherichia_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_144610380.1\|101601_102561_+	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.1e-33	34.1
WP_046196579.1\|103067_103670_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_039369308.1\|103739_104393_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_076841455.1\|104827_105070_+	hypothetical protein	NA	NA	NA	NA
WP_039369287.1\|105477_106362_-	alpha/beta fold hydrolase	G1DB77	Mycobacterium_phage	4.9e-09	41.0
WP_039369305.1\|106376_107630_-	3-(3-hydroxy-phenyl)propionate transporter MhpT	NA	NA	NA	NA
WP_039369285.1\|107688_108708_-	4-hydroxy-2-oxovalerate aldolase	E5EQ69	Micromonas_sp._RCC1109_virus	2.9e-45	33.5
WP_039369281.1\|108726_109674_-	acetaldehyde dehydrogenase (acetylating)	G9E526	Ostreococcus_lucimarinus_virus	9.6e-35	34.2

DBSCAN-SWA_10

115725 : 116583

Tetraselmis_viridis_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046196580.1\|115725_116583_+	phage Gp37/Gp68 family protein	M4R142	Tetraselmis_viridis_virus	1.3e-62	47.6

DBSCAN-SWA_11

141586 : 142282

Vibrio_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039369209.1\|141586_142282_+	ParA family protein	K7R2R7	Vibrio_phage	7.5e-21	30.9

DBSCAN-SWA_12

148856 : 150155

Megavirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039372257.1\|148856_150155_+	adenylosuccinate synthase	A0A2P1EKE7	Megavirus	6.5e-58	33.8

DBSCAN-SWA_13

154418 : 158882

Leptospira_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046196744.1\|154418_155675_+	efflux RND transporter periplasmic adaptor subunit	S5VL44	Leptospira_phage	8.0e-05	24.3
WP_039360662.1\|155690_158882_+	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	4.5e-44	22.9

DBSCAN-SWA_14

175526 : 176297

Agrobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039362813.1\|175526_176297_+	hypothetical protein	A0A2L0V0Z6	Agrobacterium_phage	1.1e-07	33.0

DBSCAN-SWA_15

182561 : 183086

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021161966.1\|182561_183086_+	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A1B1IUF0	uncultured_Mediterranean_phage	1.3e-44	53.7

DBSCAN-SWA_16

192690 : 194520

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039343159.1\|192690_194520_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	2.6e-12	42.4

DBSCAN-SWA_17

197719 : 202163

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039343176.1\|197719_199387_+	AMP-binding protein	A0A2H4PQU7	Staphylococcus_phage	7.0e-81	40.1
WP_039343179.1\|199409_200177_+	3-hydroxyacyl-CoA dehydrogenase	NA	NA	NA	NA
WP_039343181.1\|200195_201386_+	acetyl-CoA C-acyltransferase	NA	NA	NA	NA
WP_039343184.1\|201509_202163_-	response regulator transcription factor	W8CYM9	Bacillus_phage	6.6e-11	35.8

DBSCAN-SWA_18

221345 : 222662

Geobacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039343229.1\|221345_222662_+	thymidine phosphorylase	A0A0H3UZD4	Geobacillus_virus	7.2e-73	39.9

DBSCAN-SWA_19

232606 : 234562

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095145700.1\|232606_234562_-	AMP-binding protein	A0A2H4PQU7	Staphylococcus_phage	4.0e-43	28.4

DBSCAN-SWA_20

258254 : 258926

Acanthocystis_turfacea_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039341390.1\|258254_258926_+	nitroreductase	M1I6Q5	Acanthocystis_turfacea_Chlorella_virus	1.4e-19	28.7

DBSCAN-SWA_21

292400 : 293993

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039341293.1\|292400_293993_-	response regulator	W8CYF6	Bacillus_phage	6.6e-20	26.4

DBSCAN-SWA_22

299300 : 301046

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039341278.1\|299300_301046_+	carbamoyltransferase	A0A1B1ITZ5	uncultured_Mediterranean_phage	3.1e-47	29.8

DBSCAN-SWA_23

308558 : 311952

Ectocarpus_siliculosus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371355.1\|308558_310874_+	PAS domain-containing protein	Q8QKV7	Ectocarpus_siliculosus_virus	4.6e-22	25.4
WP_039371388.1\|310905_311952_-	SDR family oxidoreductase	A0A2K9KZK0	Tupanvirus	5.9e-78	44.5

DBSCAN-SWA_24

316039 : 320211

Trichoplusia_ni_ascovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371341.1\|316039_316897_+	glucose 1-dehydrogenase	A0A2N9QUX2	Trichoplusia_ni_ascovirus	2.3e-51	42.8
WP_039371338.1\|316931_317537_+	DUF4142 domain-containing protein	NA	NA	NA	NA
WP_039371335.1\|317594_318203_+	DUF892 family protein	NA	NA	NA	NA
WP_039371332.1\|318274_319555_-	divalent metal cation transporter	NA	NA	NA	NA
WP_046196867.1\|319551_320211_-	UdgX family uracil-DNA binding protein	A0A127AW33	Bacillus_phage	2.2e-14	29.4

DBSCAN-SWA_25

324210 : 324642

Macacine_betaherpesvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371315.1\|324210_324642_-	CBS domain-containing protein	A0A2I6B2H4	Macacine_betaherpesvirus	5.0e-15	37.1

DBSCAN-SWA_26

327909 : 336141

Tupanvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371289.1\|327909_330015_+	catalase HPII	A0A2K9L0T1	Tupanvirus	2.0e-141	49.5
WP_039371286.1\|330027_330531_+	DUF421 domain-containing protein	NA	NA	NA	NA
WP_039371283.1\|330567_331575_+	Ku protein	NA	NA	NA	NA
WP_039371280.1\|331599_334344_+	DNA ligase D	A0A068CDF3	Rhizobium_phage	2.7e-53	39.9
WP_039371277.1\|334524_334947_+	hypothetical protein	NA	NA	NA	NA
WP_039371274.1\|335016_335391_+	DUF3022 domain-containing protein	NA	NA	NA	NA
WP_039371378.1\|335592_336141_+	type 1 glutamine amidotransferase	A0A0N7KVR4	Yellowstone_lake_phycodnavirus	1.4e-17	35.0

DBSCAN-SWA_27

347018 : 348632

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371252.1\|347018_348632_+	tryptophan 7-halogenase	A0A1Z1LWL6	Synechococcus_phage	4.5e-61	33.8

DBSCAN-SWA_28

361453 : 363013

Anomala_cuprea_entomopoxvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371225.1\|361453_363013_+	D-xylose ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.6e-10	28.9

DBSCAN-SWA_29

368060 : 373321

Planktothrix_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371203.1\|368060_368825_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	1.0e-26	36.1
WP_039371201.1\|368904_370275_+	aspartate aminotransferase family protein	A0A1V0SKB7	Klosneuvirus	1.9e-12	23.2
WP_039371365.1\|370289_371879_+	gamma-glutamyltransferase family protein	NA	NA	NA	NA
WP_007182917.1\|372328_373321_-\|transposase	IS5-like element ISBmu23 family transposase	E5E3P6	Burkholderia_phage	1.3e-186	100.0

DBSCAN-SWA_30

387692 : 391691

Trichoplusia_ni_ascovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039356016.1\|387692_388505_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	2.3e-05	26.1
WP_039356019.1\|388520_389558_+	exo-alpha-sialidase	NA	NA	NA	NA
WP_039356023.1\|389570_390086_+	glyoxalase	NA	NA	NA	NA
WP_039356026.1\|390134_390740_+	amino acid synthesis family protein	NA	NA	NA	NA
WP_039356029.1\|390746_391691_+	alpha/beta hydrolase	G9VYU4	Mycobacterium_phage	6.0e-05	37.3

DBSCAN-SWA_31

399440 : 400805

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039356045.1\|399440_400805_-	aspartate aminotransferase family protein	A0A1V0SKB7	Klosneuvirus	3.0e-21	23.3

DBSCAN-SWA_32

408122 : 409667

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039356058.1\|408122_409667_+	sugar ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.7e-15	28.3

DBSCAN-SWA_33

419904 : 424808

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039356092.1\|419904_421491_-	chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	4.8e-15	34.5
WP_039356095.1\|421631_423152_-	sensor domain-containing diguanylate cyclase	NA	NA	NA	NA
WP_039356098.1\|423512_424808_+	MFS transporter	Q6JIH2	Burkholderia_virus	3.4e-59	35.8

DBSCAN-SWA_34

445404 : 446886

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039356138.1\|445404_446886_-	MFS transporter	A0A0M3UL24	Mycobacterium_phage	6.7e-35	31.8

DBSCAN-SWA_35

454535 : 456074

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039356168.1\|454535_456074_+	chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	2.1e-07	31.5

DBSCAN-SWA_36

460373 : 462260

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039356177.1\|460373_462260_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	6.8e-16	32.3

DBSCAN-SWA_37

472211 : 474677

Apis_mellifera_filamentous_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039356243.1\|472211_472886_+	chitin-binding protein	A0A0K1Y848	Apis_mellifera_filamentous_virus	5.2e-11	29.3
WP_039356244.1\|473582_474677_+	glycosyl hydrolase	M1HYL5	Paramecium_bursaria_Chlorella_virus	2.2e-11	25.6

DBSCAN-SWA_38

485751 : 489356

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039353444.1\|485751_486780_-	TIGR00730 family Rossman fold protein	F4YCQ1	Synechococcus_phage	1.8e-10	40.6
WP_039353442.1\|486801_487137_-	cytochrome c	NA	NA	NA	NA
WP_039353440.1\|487189_488191_-	nitroreductase	NA	NA	NA	NA
WP_039353437.1\|488366_489356_+	zinc-dependent alcohol dehydrogenase family protein	A0A0G2Y405	Acanthamoeba_polyphaga_mimivirus	4.1e-20	31.9

DBSCAN-SWA_39

494589 : 495429

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039353420.1\|494589_495429_-	universal stress protein	A0A2H4J154	uncultured_Caudovirales_phage	9.1e-05	34.8

DBSCAN-SWA_40

499699 : 500740

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039353412.1\|499699_500740_+	zinc-dependent alcohol dehydrogenase family protein	E3SJ82	Synechococcus_phage	1.3e-16	27.1

DBSCAN-SWA_41

504519 : 507354

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039353398.1\|504519_507354_-	ribosome-associated ATPase/putative transporter RbbA	G3M9Y6	Bacillus_virus	4.6e-16	28.5

DBSCAN-SWA_42

511834 : 515572

Bathycoccus_sp._RCC1105_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039353385.1\|511834_513748_+	ATP-dependent metallopeptidase FtsH/Yme1/Tma family protein	E5EQU5	Bathycoccus_sp._RCC1105_virus	5.5e-106	43.8
WP_039353382.1\|513778_515572_-	adenosylcobalamin-dependent ribonucleoside-diphosphate reductase	M4QT32	Loktanella_phage	1.0e-93	37.4

DBSCAN-SWA_43

524679 : 530976

Planktothrix_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039353363.1\|524679_525471_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	1.1e-31	38.3
WP_039353360.1\|525478_526972_+	histidine ammonia-lyase	A0A1V0S940	Catovirus	1.5e-50	34.0
WP_039353358.1\|527028_527784_+	histidine utilization repressor	NA	NA	NA	NA
WP_046196877.1\|529248_530976_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.4e-15	31.6

DBSCAN-SWA_44

543564 : 550344

Acanthamoeba_polyphaga_mimivirus(25.0%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039353328.1\|543564_544548_+	alpha/beta hydrolase	A0A0G2YDK2	Acanthamoeba_polyphaga_mimivirus	9.9e-27	32.7
WP_039353323.1\|546406_547357_+	alpha/beta hydrolase	L7RDF8	Acanthamoeba_polyphaga_moumouvirus	1.3e-36	32.6
WP_039353320.1\|547579_549208_+\|holin	choline dehydrogenase	A0A1V0S9J5	Catovirus	1.7e-63	31.5
WP_039353317.1\|549654_550344_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.2e-23	30.7

DBSCAN-SWA_45

577277 : 582328

Hepacivirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039353274.1\|577277_578900_+	AMP-binding protein	Q75ZG1	Hepacivirus	5.6e-43	28.9
WP_039353272.1\|579136_582328_-	cytochrome P450	V5UQK0	Mycobacterium_phage	1.8e-69	34.1

DBSCAN-SWA_46

586639 : 587359

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039353478.1\|586639_587359_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.5e-32	34.1

DBSCAN-SWA_47

590360 : 591995

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039353239.1\|590360_591995_+	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	3.1e-33	29.3

DBSCAN-SWA_48

595765 : 598909

Leptospira_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039353229.1\|595765_598909_-	multidrug efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	1.5e-52	21.7

DBSCAN-SWA_49

607556 : 608477

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039353211.1\|607556_608477_-	L-proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	3.4e-29	28.6

DBSCAN-SWA_50

617977 : 624213

uncultured_Caudovirales_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_052760070.1\|617977_620338_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	2.0e-36	26.2
WP_082139477.1\|620344_621229_+	DUF4123 domain-containing protein	NA	NA	NA	NA
WP_144610392.1\|621267_622113_+	hypothetical protein	NA	NA	NA	NA
WP_144610395.1\|622076_622436_+	hypothetical protein	NA	NA	NA	NA
WP_011875599.1\|622656_624213_+\|transposase	IS21-like element IS408 family transposase	K4I413	Acidithiobacillus_phage	1.4e-160	55.1

DBSCAN-SWA_51

648415 : 649186

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039362621.1\|648415_649186_+	DNA-binding transcriptional repressor DeoR	A0A077SK06	Escherichia_phage	3.5e-19	31.6

DBSCAN-SWA_52

653447 : 657634

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039362629.1\|653447_654125_+	heavy metal response regulator transcription factor	W8CYM9	Bacillus_phage	9.9e-34	35.2
WP_039362631.1\|654121_655582_+	heavy metal sensor histidine kinase	W8CYF6	Bacillus_phage	7.9e-20	27.4
WP_046197074.1\|655813_657634_-	asparagine synthase (glutamine-hydrolyzing)	A0A0G2Y369	Acanthamoeba_polyphaga_mimivirus	1.9e-23	25.8

DBSCAN-SWA_53

661955 : 665204

Leptospira_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039362636.1\|661955_665204_-	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	1.9e-58	23.0

DBSCAN-SWA_54

670729 : 671479

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039362646.1\|670729_671479_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.5e-32	42.2

DBSCAN-SWA_55

701172 : 705064

Acinetobacter_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039362674.1\|701172_701673_-	(2Fe-2S)-binding protein	A0A0P0IVM8	Acinetobacter_phage	1.8e-08	27.9
WP_039362676.1\|701669_702956_-	cytochrome c	NA	NA	NA	NA
WP_039362765.1\|703293_703566_-	UBP-type zinc finger domain-containing protein	NA	NA	NA	NA
WP_039362677.1\|703792_705064_+	NAD(P)/FAD-dependent oxidoreductase	A0A2I2L5E1	Orpheovirus	9.8e-27	29.9

DBSCAN-SWA_56

709318 : 710299

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039362683.1\|709318_710299_-	alpha/beta hydrolase	A0A286MQ79	Mycobacterium_phage	8.7e-15	27.7

DBSCAN-SWA_57

726274 : 727111

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039362703.1\|726274_727111_+	alpha/beta hydrolase	A0A249XU20	Mycobacterium_phage	1.1e-07	27.1

DBSCAN-SWA_58

778508 : 781355

Agrobacterium_phage(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039342435.1\|778508_781355_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A223W0B1	Agrobacterium_phage	2.1e-122	35.6

DBSCAN-SWA_59

792550 : 793711

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371518.1\|792550_793711_-	NAD-dependent formate dehydrogenase	A0A1B1IVB5	uncultured_Mediterranean_phage	4.2e-16	25.7

DBSCAN-SWA_60

799302 : 801609

Ectocarpus_siliculosus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371541.1\|799302_801609_+	PAS domain-containing protein	Q8QKV7	Ectocarpus_siliculosus_virus	4.9e-24	27.1

DBSCAN-SWA_61

806364 : 806721

Sinorhizobium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371561.1\|806364_806721_-	DUF3175 domain-containing protein	A0A0F6TH17	Sinorhizobium_phage	5.5e-20	57.3

DBSCAN-SWA_62

830128 : 830905

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371603.1\|830128_830905_-	glucose 1-dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	9.0e-23	35.2

DBSCAN-SWA_63

835819 : 836956

Oenococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371611.1\|835819_836956_+	muconate cycloisomerase	Q6A202	Oenococcus_phage	7.5e-10	23.5

DBSCAN-SWA_64

840987 : 841758

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371625.1\|840987_841758_+	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase	W8CYX9	Bacillus_phage	4.9e-05	45.8

DBSCAN-SWA_65

848832 : 849669

Pelagibacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371656.1\|848832_849669_+	spermidine synthase	M1ICM1	Pelagibacter_phage	3.7e-06	33.0

DBSCAN-SWA_66

861103 : 862093

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371687.1\|861103_862093_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.8e-34	43.3

DBSCAN-SWA_67

876948 : 877407

Acinetobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371974.1\|876948_877407_-	(2Fe-2S)-binding protein	A0A0P0IVM8	Acinetobacter_phage	1.1e-07	31.3

DBSCAN-SWA_68

891480 : 895091

Burkholderia_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371976.1\|891480_892518_-	LysR family transcriptional regulator	Q6JIH3	Burkholderia_virus	1.4e-10	24.9
WP_039371732.1\|892600_893344_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_039371734.1\|893549_895091_+	PLP-dependent aminotransferase family protein	A0A1X9I5H2	Streptococcus_phage	6.8e-14	26.2

DBSCAN-SWA_69

904561 : 910221

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371755.1\|904561_906292_+	chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	2.6e-14	35.8
WP_046197096.1\|906326_906842_+	hypothetical protein	NA	NA	NA	NA
WP_046197097.1\|906942_907491_+	hypothetical protein	NA	NA	NA	NA
WP_052760063.1\|907487_907892_+	hypothetical protein	NA	NA	NA	NA
WP_039371761.1\|908652_910221_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	7.6e-13	37.2

DBSCAN-SWA_70

935055 : 941863

Planktothrix_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076841483.1\|935055_936867_-	amino acid ABC transporter permease/ATP-binding protein	G9BWD6	Planktothrix_phage	3.3e-28	36.3
WP_039372021.1\|936866_938189_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_039371798.1\|938232_939234_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_039371802.1\|939385_941863_-	TonB-dependent receptor	A0A0P0I887	Acinetobacter_phage	1.4e-16	33.2

DBSCAN-SWA_71

946771 : 948469

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371815.1\|946771_948469_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-16	32.9

DBSCAN-SWA_72

966370 : 967210

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371858.1\|966370_967210_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.5e-27	37.6

DBSCAN-SWA_73

987437 : 990052

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371894.1\|987437_988199_+	response regulator transcription factor	W8CYM9	Bacillus_phage	2.2e-29	35.5
WP_082139470.1\|988300_990052_+	PAS domain S-box protein	A0A1V0SGX0	Hokovirus	4.2e-12	23.1

DBSCAN-SWA_74

1005177 : 1006179

Burkholderia_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371915.1\|1005177_1006179_-	LysR family transcriptional regulator	Q6JIH3	Burkholderia_virus	1.6e-24	27.7

DBSCAN-SWA_75

1010607 : 1015288

Aeromonas_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039371920.1\|1010607_1011903_-	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	6.2e-101	53.5
WP_039371921.1\|1012079_1012961_-	glycine betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_039371928.1\|1013114_1014002_-	proline/glycine betaine ABC transporter permease	NA	NA	NA	NA
WP_039371930.1\|1013998_1015288_-	glycine betaine/L-proline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.1e-25	37.4

DBSCAN-SWA_76

1021404 : 1021974

Morganella_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039370025.1\|1021404_1021974_-	lipocalin family protein	A0A1W6JNX6	Morganella_phage	2.9e-18	43.1

DBSCAN-SWA_77

1028512 : 1032736

Orpheovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039370001.1\|1028512_1029730_+	class I SAM-dependent methyltransferase	A0A2I2L5L3	Orpheovirus	1.0e-33	34.1
WP_039369997.1\|1029731_1030265_+	hypothetical protein	NA	NA	NA	NA
WP_009687752.1\|1030359_1030530_+	DUF2256 domain-containing protein	NA	NA	NA	NA
WP_039369993.1\|1031089_1031905_+	hypothetical protein	NA	NA	NA	NA
WP_039369991.1\|1032004_1032736_+	GTP cyclohydrolase	A0A1C3NFQ1	Phage_NCTB	3.6e-58	48.9

DBSCAN-SWA_78

1036322 : 1039104

Indivirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039369980.1\|1036322_1037852_-	cryptochrome/photolyase family protein	A0A1V0SE91	Indivirus	2.6e-50	28.7
WP_039369977.1\|1038132_1039104_+	MerR family transcriptional regulator	Q9EYF2	Enterobacteria_phage	3.9e-07	38.6

DBSCAN-SWA_79

1048235 : 1059556

uncultured_virus(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039369948.1\|1048235_1048799_+	Hsp20/alpha crystallin family protein	A0A1B2LRT2	Wolbachia_phage	5.2e-12	31.7
WP_039369946.1\|1049339_1050962_-	chaperonin GroEL	A0A240F779	uncultured_virus	2.3e-174	60.6
WP_144610426.1\|1051039_1051327_-	co-chaperone GroES	A0A221S322	uncultured_virus	6.9e-13	45.8
WP_039369940.1\|1051721_1054052_-	EAL domain-containing protein	G3MA91	Bacillus_virus	4.9e-16	36.1
WP_039369938.1\|1054105_1056208_-	EAL domain-containing protein	A0A127AWB9	Bacillus_phage	4.5e-08	30.2
WP_039369936.1\|1056641_1058339_-	M4 family metallopeptidase	NA	NA	NA	NA
WP_007182917.1\|1058563_1059556_-\|transposase	IS5-like element ISBmu23 family transposase	E5E3P6	Burkholderia_phage	1.3e-186	100.0

DBSCAN-SWA_80

1062666 : 1063965

Leuconostoc_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355552.1\|1062666_1063197_+	toxin	A0A097BYE2	Leuconostoc_phage	1.0e-06	26.0
WP_039355550.1\|1063215_1063965_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	4.9e-18	31.3

DBSCAN-SWA_81

1069817 : 1070624

Feldmannia_irregularis_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355578.1\|1069817_1070624_+	response regulator transcription factor	Q6XM27	Feldmannia_irregularis_virus	3.0e-05	25.0

DBSCAN-SWA_82

1074899 : 1076147

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355542.1\|1074899_1076147_+	carboxymethylenebutenolidase	S4VS37	Pandoravirus	1.7e-10	30.9

DBSCAN-SWA_83

1106504 : 1107548

Shigella_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355479.1\|1106504_1107548_+	glycosyltransferase family 2 protein	U5P087	Shigella_phage	6.7e-90	56.8

DBSCAN-SWA_84

1112339 : 1113773

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355470.1\|1112339_1113773_+	MFS transporter	A0A0M3UL24	Mycobacterium_phage	7.7e-28	31.3

DBSCAN-SWA_85

1119461 : 1125547

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355462.1\|1119461_1120664_+	AAA domain-containing protein	A0A1D7RMM0	Synechococcus_phage	4.2e-19	30.8
WP_039355460.1\|1120668_1122372_+	cobalamin biosynthesis protein CobT	A0A2H4P735	Pseudomonas_phage	2.4e-20	30.0
WP_039355458.1\|1122627_1123731_+	prolyl oligopeptidase family serine peptidase	NA	NA	NA	NA
WP_039355456.1\|1123777_1125547_-	histidine kinase	B5LWN8	Feldmannia_species_virus	1.9e-07	29.6

DBSCAN-SWA_86

1129744 : 1130368

Brazilian_cedratvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355445.1\|1129744_1130368_+	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	4.5e-09	28.2

DBSCAN-SWA_87

1135662 : 1139437

Burkholderia_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355438.1\|1135662_1136568_-	LysR family transcriptional regulator	Q6JIH3	Burkholderia_virus	6.4e-20	32.9
WP_039355435.1\|1136734_1137277_+	hypothetical protein	NA	NA	NA	NA
WP_039355433.1\|1137283_1137610_+	hypothetical protein	NA	NA	NA	NA
WP_039355431.1\|1137628_1138474_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_039355429.1\|1138690_1139437_+	glucose 1-dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	7.6e-19	31.0

DBSCAN-SWA_88

1142474 : 1143023

Turkeypox_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355423.1\|1142474_1143023_-	glutathione peroxidase	A0A0M5HSM9	Turkeypox_virus	3.6e-10	31.1

DBSCAN-SWA_89

1150889 : 1151915

Cyanophage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039360429.1\|1150889_1151915_+	phosphate ABC transporter substrate-binding protein PstS	M4QHS4	Cyanophage	1.0e-45	36.9

DBSCAN-SWA_90

1155667 : 1157164

Diachasmimorpha_longicaudata_entomopoxvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076841477.1\|1155667_1157164_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	4.2e-53	34.2

DBSCAN-SWA_91

1167832 : 1173727

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355657.1\|1167832_1173727_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	1.5e-191	38.6

DBSCAN-SWA_92

1178556 : 1180317

Flavobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355677.1\|1178556_1180317_-	cytochrome c oxidase subunit I	R9VX24	Flavobacterium_phage	9.8e-33	49.3

DBSCAN-SWA_93

1184235 : 1185177

Burkholderia_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355688.1\|1184235_1185177_-	LysR family transcriptional regulator	Q6JIH3	Burkholderia_virus	1.1e-14	27.8

DBSCAN-SWA_94

1192885 : 1204777

Feldmannia_irregularis_virus(20.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355697.1\|1192885_1193722_+	response regulator transcription factor	Q6XM27	Feldmannia_irregularis_virus	5.7e-07	26.2
WP_039355700.1\|1193714_1196063_+	sensor histidine kinase	A0A1V0SGX0	Hokovirus	1.3e-19	32.4
WP_039355702.1\|1196201_1197290_-	sugar ABC transporter permease YjfF	NA	NA	NA	NA
WP_039355704.1\|1197286_1198327_-	ABC transporter permease	NA	NA	NA	NA
WP_039355706.1\|1198323_1199838_-	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.2e-16	25.5
WP_039355709.1\|1199912_1200875_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_076841476.1\|1201129_1201324_-	hypothetical protein	NA	NA	NA	NA
WP_039355715.1\|1201528_1202575_+	DNA topoisomerase IB	A0A0G2Y4T8	Acanthamoeba_polyphaga_mimivirus	6.2e-43	32.7
WP_039355719.1\|1202859_1203168_-	H-NS histone family protein	NA	NA	NA	NA
WP_039355722.1\|1203298_1203532_-	flagellar transcriptional regulator FlhD	NA	NA	NA	NA
WP_039355724.1\|1203892_1204777_+	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	3.2e-69	46.2

DBSCAN-SWA_95

1208128 : 1211217

Edwardsiella_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355732.1\|1208128_1209061_-	KpsF/GutQ family sugar-phosphate isomerase	A0A0B6VSY5	Edwardsiella_phage	5.4e-22	33.8
WP_039355735.1\|1209041_1209839_-	3-deoxy-manno-octulosonate cytidylyltransferase	NA	NA	NA	NA
WP_039355738.1\|1210371_1211217_-	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	5.5e-50	41.6

DBSCAN-SWA_96

1224960 : 1228524

Burkholderia_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046543601.1\|1224960_1226430_+	glycine betaine/L-proline transporter ProP	Q6JIH2	Burkholderia_virus	1.0e-59	32.4
WP_039347895.1\|1226512_1227337_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_039347715.1\|1227531_1228524_-	LysR family transcriptional regulator	Q6JIH3	Burkholderia_virus	2.0e-27	28.3

DBSCAN-SWA_97

1233183 : 1233894

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039347725.1\|1233183_1233894_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.6e-29	42.5

DBSCAN-SWA_98

1243260 : 1244835

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039347762.1\|1243260_1244835_+	acyl-CoA ligase (AMP-forming), exosortase A system-associated	A0A2K9KZV5	Tupanvirus	6.3e-23	23.7

DBSCAN-SWA_99

1250819 : 1251833

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039347776.1\|1250819_1251833_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	3.7e-08	24.2

DBSCAN-SWA_100

1259096 : 1262457

Prochlorococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039347800.1\|1259096_1259918_-	SDR family NAD(P)-dependent oxidoreductase	A0A0K0KVL6	Prochlorococcus_phage	1.5e-07	28.9
WP_039347903.1\|1260171_1260714_+	hypothetical protein	NA	NA	NA	NA
WP_039347802.1\|1261377_1262457_+	linear amide C-N hydrolase	A0A2K9L5Y5	Tupanvirus	1.7e-19	28.6

DBSCAN-SWA_101

1266119 : 1267232

Faustovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039347812.1\|1266119_1267232_+	histidinol-phosphate transaminase	A0A1X7QHI1	Faustovirus	1.9e-10	25.3

DBSCAN-SWA_102

1286130 : 1287537

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039362461.1\|1286130_1287537_-	MFS transporter	A0A0M3UL24	Mycobacterium_phage	8.9e-37	32.4

DBSCAN-SWA_103

1296475 : 1300339

uncultured_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039362441.1\|1296475_1297393_-	hypothetical protein	A0A218MNG2	uncultured_virus	5.8e-05	23.8
WP_039362438.1\|1297724_1298387_-	glutathione S-transferase family protein	NA	NA	NA	NA
WP_039362501.1\|1298510_1299491_+	YafY family transcriptional regulator	NA	NA	NA	NA
WP_039362436.1\|1299694_1300339_-	HD domain-containing protein	A0A146JEM2	Tokyovirus	3.0e-08	30.4

DBSCAN-SWA_104

1308880 : 1313332

Bacillus_virus(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039362413.1\|1308880_1309735_+	ABC transporter permease	G3M9Y4	Bacillus_virus	2.5e-18	26.9
WP_039362411.1\|1309731_1310553_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.6e-25	34.3
WP_039362409.1\|1310760_1311291_-	OsmC family protein	NA	NA	NA	NA
WP_039362406.1\|1311766_1313332_-	HAMP domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	1.1e-14	37.9

DBSCAN-SWA_105

1316600 : 1324751

Tupanvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039362393.1\|1316600_1317551_+	SDR family oxidoreductase	A0A2K9KZK0	Tupanvirus	1.5e-83	48.6
WP_039362390.1\|1317758_1319069_+	diaminobutyrate--2-oxoglutarate transaminase family protein	A0A1V0SKB7	Klosneuvirus	5.2e-23	25.6
WP_039362498.1\|1319145_1320132_+	taurine catabolism dioxygenase TauD	NA	NA	NA	NA
WP_039362388.1\|1320323_1324751_+	type I polyketide synthase	D0R7J2	Paenibacillus_phage	9.3e-32	33.3

DBSCAN-SWA_106

1343114 : 1368627

Tupanvirus(60.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355058.1\|1343114_1347035_+	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	2.6e-70	30.8
WP_076841474.1\|1347031_1356136_+	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	1.4e-69	20.1
WP_046543599.1\|1356223_1365718_+	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	7.8e-153	26.5
WP_039355063.1\|1365714_1366371_+	glycosyl transferase	A0A218MMA0	uncultured_virus	1.4e-21	28.7
WP_046196791.1\|1366424_1366907_+	hypothetical protein	NA	NA	NA	NA
WP_039355066.1\|1366923_1368627_+	cyclic peptide export ABC transporter	F2Y1V5	Organic_Lake_phycodnavirus	3.9e-10	25.2

DBSCAN-SWA_107

1389612 : 1391078

Cedratvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355122.1\|1389612_1390314_-	ABC transporter ATP-binding protein	A0A1M7XV31	Cedratvirus	4.6e-10	28.7
WP_021160139.1\|1390310_1391078_-	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	8.9e-15	29.5

DBSCAN-SWA_108

1396969 : 1398367

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355140.1\|1396969_1398367_-	aspartate aminotransferase family protein	A0A2D1G879	Mycobacterium_phage	5.2e-13	34.2

DBSCAN-SWA_109

1410479 : 1413581

Streptomyces_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355167.1\|1410479_1411700_-	thioredoxin	A0A1J0GW78	Streptomyces_phage	1.1e-14	43.5
WP_039355171.1\|1411778_1413581_-	ABC transporter ATP-binding protein/permease	G3M9Y6	Bacillus_virus	7.9e-14	30.3

DBSCAN-SWA_110

1420340 : 1422727

Brazilian_cedratvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355182.1\|1420340_1421330_+	D-2-hydroxyacid dehydrogenase	A0A2R8FDS8	Brazilian_cedratvirus	3.4e-19	33.6
WP_039355184.1\|1421419_1422727_+	MFS transporter	Q6JIH2	Burkholderia_virus	3.2e-49	29.3

DBSCAN-SWA_111

1426542 : 1430808

Mycobacterium_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355193.1\|1426542_1427418_-	alpha/beta fold hydrolase	A0A1I9SAY0	Mycobacterium_phage	2.8e-12	30.5
WP_039355195.1\|1427487_1428744_-	3-(3-hydroxy-phenyl)propionate transporter MhpT	NA	NA	NA	NA
WP_039355196.1\|1428833_1429853_-	4-hydroxy-2-oxovalerate aldolase	E5EQ69	Micromonas_sp._RCC1109_virus	4.4e-46	32.0
WP_039355197.1\|1429866_1430808_-	acetaldehyde dehydrogenase (acetylating)	G9E526	Ostreococcus_lucimarinus_virus	1.0e-33	33.6

DBSCAN-SWA_112

1440607 : 1441957

Enterobacteria_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355207.1\|1440607_1441957_-	RNA-directed DNA polymerase	Q7M2A9	Enterobacteria_phage	2.9e-08	27.7

DBSCAN-SWA_113

1451919 : 1452885

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355223.1\|1451919_1452885_-	SDR family oxidoreductase	A0A1D8EQE2	Escherichia_phage	2.7e-08	24.3

DBSCAN-SWA_114

1459876 : 1460962

Enterobacteria_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355286.1\|1459876_1460962_+	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	3.8e-19	28.4

DBSCAN-SWA_115

1472170 : 1478477

Hokovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_052760046.1\|1472170_1473886_+	GAF domain-containing hybrid sensor histidine kinase/response regulator	A0A1V0SGX0	Hokovirus	1.3e-13	23.9
WP_039355306.1\|1474012_1475053_-	alpha/beta hydrolase	M1PGN2	Moumouvirus	1.8e-58	40.3
WP_039355308.1\|1475118_1475544_-	organic hydroperoxide resistance protein	NA	NA	NA	NA
WP_039355310.1\|1475768_1476335_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_039355312.1\|1476623_1478477_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	7.4e-31	27.3

DBSCAN-SWA_116

1485843 : 1487953

Mycoplasma_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039355327.1\|1485843_1486803_-	ABC transporter permease subunit	Q6GZ02	Mycoplasma_phage	3.7e-10	24.9
WP_046543598.1\|1486813_1487953_-	polyamine ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	8.3e-25	33.5

DBSCAN-SWA_117

1498668 : 1502777

Pandoravirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_039364494.1\|1498668_1501728_-	FAD-binding oxidoreductase	S4VRT3	Pandoravirus	5.1e-05	26.7
WP_039364496.1\|1501880_1502777_+	LysR family transcriptional regulator	Q6JIH3	Burkholderia_virus	4.4e-21	28.9

DBSCAN-SWA_118

1526328 : 1527360

Clostridium_botulinum_C_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_052760043.1\|1526328_1527360_-	hypothetical protein	Q332C0	Clostridium_botulinum_C_phage	1.9e-12	22.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_CP042167

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

163150 : 209906

Bacillus_phage(33.33%)

integrase,transposase

attL 170904:170918|attR 210800:210814

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_077186797.1\|163150_164215_+\|transposase	IS4 family transposase	Q9JMP3	Wolbachia_phage	9.4e-47	32.8
WP_027810101.1\|164262_164739_+\|transposase	transposase	NA	NA	NA	NA
WP_027810102.1\|164714_165065_+	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	2.5e-17	39.4
WP_011875599.1\|165424_166981_+\|transposase	IS21-like element IS408 family transposase	K4I413	Acidithiobacillus_phage	1.4e-160	55.1
WP_012213993.1\|170309_171098_+	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	8.8e-34	34.1
170904:170918	attL	NA	NA	NA	NA
WP_143282329.1\|173071_173443_-	hypothetical protein	NA	NA	NA	NA
WP_075687087.1\|174323_174611_-	DUF4148 domain-containing protein	NA	NA	NA	NA
WP_034175672.1\|174844_175768_-	copper homeostasis membrane protein CopD	NA	NA	NA	NA
WP_027810007.1\|175773_176160_-	copper homeostasis periplasmic binding protein CopC	NA	NA	NA	NA
WP_089444650.1\|176244_177117_-	copper resistance protein B	NA	NA	NA	NA
WP_027810005.1\|177125_179156_-	copper resistance system multicopper oxidase	NA	NA	NA	NA
WP_027810004.1\|179605_180277_+	heavy metal response regulator transcription factor	W8CYM9	Bacillus_phage	6.8e-27	32.9
WP_080289663.1\|180273_181692_+	heavy metal sensor histidine kinase	W8CYF6	Bacillus_phage	2.1e-17	28.4
WP_080289662.1\|181786_184222_-	heavy metal translocating P-type ATPase	A0A218MNH6	uncultured_virus	6.8e-85	35.1
WP_046544052.1\|184432_185371_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_027810002.1\|185520_186669_+	porin	NA	NA	NA	NA
WP_027810000.1\|187926_189597_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_027809999.1\|190131_190857_+	hypothetical protein	NA	NA	NA	NA
WP_027809998.1\|190879_191383_-	hypothetical protein	NA	NA	NA	NA
WP_027809997.1\|191447_191723_-	DUF4148 domain-containing protein	NA	NA	NA	NA
WP_027809996.1\|192038_193199_+	porin	NA	NA	NA	NA
WP_080357577.1\|193404_193617_-	hypothetical protein	NA	NA	NA	NA
WP_027809994.1\|193946_194231_+	DUF4148 domain-containing protein	NA	NA	NA	NA
WP_027809993.1\|194313_195738_-	heavy metal sensor histidine kinase	W8CYF6	Bacillus_phage	7.2e-26	30.0
WP_006490455.1\|195734_196418_-	heavy metal response regulator transcription factor IrlR	W8CYM9	Bacillus_phage	4.5e-34	34.2
WP_027809992.1\|196417_199630_-	CusA/CzcA family heavy metal efflux RND transporter	S5VTK5	Leptospira_phage	1.4e-74	24.3
WP_039349346.1\|199758_201228_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_039349349.1\|201254_202562_-	TolC family protein	NA	NA	NA	NA
WP_034175768.1\|203856_204189_-	zinc ribbon domain-containing protein	NA	NA	NA	NA
WP_080289699.1\|204234_206628_-	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	2.9e-136	45.5
WP_027810736.1\|207220_208207_+	cation transporter	NA	NA	NA	NA
WP_080353646.1\|208248_208620_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_080001177.1\|208637_209906_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	3.5e-40	43.9
210800:210814	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP042164

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP042165

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP042166

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

4. NZ_CP042167

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection