CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_AP019752	Staphylococcus aureus strain JRA307 plasmid pJRA307-1, complete sequence	0 crisprs	NA	0	0	0	0
NZ_AP019751	Staphylococcus aureus strain JRA307	13 crisprs	WYL,csa3,cas3,DEDDh,DinG	7	4	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_AP019751_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019751_1

199192-199276

Orphan

Consensus_repeat	Method
TTCTACAGGCAATGCAAGTTGGGGTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP019751_1

>merge|NZ_AP019751|1|199192-199276|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGTGTGGGCCCCAACAAAGAGAAATTGGATTCCCAATTTCTACAGACAATGCAAGTTGGGGTG

>NZ_AP019751|1|1|199192-199276|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGTG	TGGGCCCCAACAAAGAGAAATTGGATTCCCAAT
TTCTACAGACAATGCAAGTTGGGGTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019751.1\|WP_001013481.1\|198083_199043_+\|cation-transporter	unknown	unknown	gnl\|CDD\|224151
NZ_AP019751.1\|WP_000826671.1\|201326_202301_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270271
NZ_AP019751.1\|WP_000356963.1\|199337_199541_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_000171919.1\|199718_200231_+\|DUF4242-domain-containing-protein	unknown	unknown	gnl\|CDD\|379428
NZ_AP019751.1\|WP_000723452.1\|193597_194743_+\|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	unknown	unknown	gnl\|CDD\|223458
NZ_AP019751.1\|WP_000825101.1\|190760_191318_+\|sugar-transferase	unknown	unknown	gnl\|CDD\|225059
NZ_AP019751.1\|WP_001238807.1\|188272_189511_+\|oligosaccharide-flippase-family-protein	unknown	unknown	gnl\|CDD\|240532
NZ_AP019751.1\|WP_000590847.1\|200572_201313_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224041
NZ_AP019751.1\|WP_001237002.1\|195140_195524_-\|YbaN-family-protein	unknown	unknown	gnl\|CDD\|377291
NZ_AP019751.1\|WP_000779494.1\|192258_193521_+\|nucleotide-sugar-dehydrogenase	unknown	unknown	gnl\|CDD\|223749
NZ_AP019751.1\|WP_000706137.1\|204852_205878_+\|NAD-dependent-formate-dehydrogenase	unknown	unknown	gnl\|CDD\|181041
NZ_AP019751.1\|WP_001291010.1\|189544_190750_+\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340825
NZ_AP019751.1\|WP_000290397.1\|195950_197438_+\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143435
NZ_AP019751.1\|WP_000171644.1\|203071_204103_+\|acyl-CoA/acyl-ACP-dehydrogenase	unknown	unknown	gnl\|CDD\|224871
NZ_AP019751.1\|WP_000197961.1\|202297_203059_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223673
NZ_AP019751.1\|WP_000826862.1\|206263_207514_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340887
NZ_AP019751.1\|WP_000605278.1\|207960_215136_+\|amino-acid-adenylation-domain-containing-protein	unknown	unknown	gnl\|CDD\|237108
NZ_AP019751.1\|WP_001230681.1\|191317_192205_+\|capsular-polysaccharide-type-5/8-biosynthesis-epimerase-CapN	unknown	unknown	gnl\|CDD\|187543
NZ_AP019751.1\|WP_001092004.1\|204319_204679_+\|DUF2294-domain-containing-protein	unknown	unknown	gnl\|CDD\|227896
NZ_AP019751.1\|WP_000480603.1\|194807_195134_-\|staphylobilin-forming-heme-oxygenase-IsdI	unknown	unknown	gnl\|CDD\|183968

Protein	Function_ID	Function_description	E-value
NZ_AP019751.1\|WP_000826671.1\|201326_202301_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270271	cd13553, PBP2_NrtA_CpmA_like, Substrate binding domain of ABC-type nitrate/bicarbonate transporters, a member of the type 2 periplasmic binding fold superfamily. This subfamily includes nitrate (NrtA) and bicarbonate (CmpA) receptors. These domains are found in eubacterial perisplamic-binding proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. These binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.99971e-50
NZ_AP019751.1\|WP_001013481.1\|198083_199043_+\|cation-transporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	3.08716e-108
NZ_AP019751.1\|WP_000171919.1\|199718_200231_+\|DUF4242-domain-containing-protein	gnl\|CDD\|379428	pfam14026, DUF4242, Protein of unknown function (DUF4242). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 90 and 170 amino acids in length. There is a single completely conserved residue C that may be functionally important.	2.56603e-26
NZ_AP019751.1\|WP_000723452.1\|193597_194743_+\|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	gnl\|CDD\|223458	COG0381, WecB, UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane].	0
NZ_AP019751.1\|WP_000825101.1\|190760_191318_+\|sugar-transferase	gnl\|CDD\|225059	COG2148, WcaJ, Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane].	3.22743e-86
NZ_AP019751.1\|WP_001238807.1\|188272_189511_+\|oligosaccharide-flippase-family-protein	gnl\|CDD\|240532	cd13127, MATE_tuaB_like, Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins. This family might function as a translocase for lipopolysaccharides and participate in the biosynthesis of cell wall components such as teichuronic acid. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	1.56476e-21
NZ_AP019751.1\|WP_000590847.1\|200572_201313_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	1.69369e-112
NZ_AP019751.1\|WP_001237002.1\|195140_195524_-\|YbaN-family-protein	gnl\|CDD\|377291	pfam04304, DUF454, Protein of unknown function (DUF454). Predicted membrane protein.	3.10235e-41
NZ_AP019751.1\|WP_000779494.1\|192258_193521_+\|nucleotide-sugar-dehydrogenase	gnl\|CDD\|223749	COG0677, WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane].	0
NZ_AP019751.1\|WP_000706137.1\|204852_205878_+\|NAD-dependent-formate-dehydrogenase	gnl\|CDD\|181041	PRK07574, PRK07574, NAD-dependent formate dehydrogenase.	0
NZ_AP019751.1\|WP_001291010.1\|189544_190750_+\|glycosyltransferase-family-4-protein	gnl\|CDD\|340825	cd03794, GT4_WbuB-like, Escherichia coli WbuB and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.	2.36047e-71
NZ_AP019751.1\|WP_000290397.1\|195950_197438_+\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143435	cd07117, ALDH_StaphAldA1, Uncharacterized Staphylococcus aureus AldA1 (SACOL0154) aldehyde dehydrogenase-like. Uncharacterized aldehyde dehydrogenase from Staphylococcus aureus (AldA1, locus SACOL0154) and other similar sequences are present in this CD.	0
NZ_AP019751.1\|WP_000171644.1\|203071_204103_+\|acyl-CoA/acyl-ACP-dehydrogenase	gnl\|CDD\|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	2.35031e-20
NZ_AP019751.1\|WP_000197961.1\|202297_203059_+\|ABC-transporter-permease	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	1.22607e-73
NZ_AP019751.1\|WP_000826862.1\|206263_207514_+\|MFS-transporter	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.61322e-72
NZ_AP019751.1\|WP_000605278.1\|207960_215136_+\|amino-acid-adenylation-domain-containing-protein	gnl\|CDD\|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NZ_AP019751.1\|WP_001230681.1\|191317_192205_+\|capsular-polysaccharide-type-5/8-biosynthesis-epimerase-CapN	gnl\|CDD\|187543	cd05232, UDP_G4E_4_SDR_e, UDP-glucose 4 epimerase, subgroup 4, extended (e) SDRs. UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), is a homodimeric extended SDR. It catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. This subgroup is comprised of bacterial proteins, and includes the Staphylococcus aureus capsular polysaccharide Cap5N, which may have a role in the synthesis of UDP-N-acetyl-d-fucosamine. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	6.90937e-118
NZ_AP019751.1\|WP_001092004.1\|204319_204679_+\|DUF2294-domain-containing-protein	gnl\|CDD\|227896	COG5609, COG5609, Uncharacterized conserved protein [Function unknown].	6.06834e-49
NZ_AP019751.1\|WP_000480603.1\|194807_195134_-\|staphylobilin-forming-heme-oxygenase-IsdI	gnl\|CDD\|183968	PRK13313, PRK13313, staphylobilin-forming heme oxygenase IsdI.	1.40112e-64

>NZ_AP019751.1|WP_001013481.1|198083_199043_+|cation-transporter
MNGKKANTINRYKYFHHVNHQKIQQSSKKTLWASLIITLLFTVIEFVGGLVSNSLALLSDSFHMLSDVLALGLSMLAIYFASKKPTARYTFGYLRFEILAAFLNGLALIVISIWILYEAIVRIIYPQPIESGIMFMIASIGLLVNIILTIILVRSLKQEDNINIQSALWHFMGDLLNSIGVIVAVVLIYFTGWRIIDPIISIVISLIILRGGYKITRNAWLILMESVPQHLDTDQIMADIKNIDGILDVHEFHLWSITTEHYSLSAHVVLDKKYEGDDYQAIDQVSSLLKEKYGIAHSTLQIENLQLNPLDEPYFDKLT
>NZ_AP019751.1|WP_000290397.1|195950_197438_+|aldehyde-dehydrogenase-family-protein
MAVNVRDYIAENYGLFINGEFVKGSSDETIEVTNPATGETLSHITRAKDKDVDHAVKVAQEAFESWSLTSKSERAQMLRDIGDKLMAQKDKIAMIETLNNGKPIRETTAIDIPFAARHFHYFASVIETEEGTVNDIDKDTMSIVRHEPIGVVGAVVAWNFPMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEVAKIFQEVLPKGVVNILTGKGSESGNAIFNHDGVDKLSFTGSTDVGYQVAEAAAKHLVPATLELGGKSANIILDDANLDLAVEGIQLGILFNQGEVCSAGSRLLVHEKIYDQLVPRLQEAFSNIKVGDPQDEATQMGSQTGKDQLDKIQSYIDAAKESDAQILAGGHRLTENGLDKGFFFEPTLIAVPDNHHKLAQEEIFGPVLTVIKVKDDQEAIDIANDSEYGLAGGVFSQNITRALNIAKAVRTGRIWINTYNQVPEGAPFGGYKKSGIGRETYKGALSNYQQVKNIYIDTSNALKGLY
>NZ_AP019751.1|WP_001237002.1|195140_195524_-|YbaN-family-protein
MRLILIVIGLIFTALGIAGAVLPLLPTTPFLLVAVFCFARSSDRFYNWLINQKIYKEYVENFYLHRGYTLQQKIKILISLYIVIGFSIYMVDVLAVRIGLIIMVIIQTAVLFTFVKTLPKSNHKIEE
>NZ_AP019751.1|WP_000480603.1|194807_195134_-|staphylobilin-forming-heme-oxygenase-IsdI
MFMAENRLQLQKGSAEETIERFYNRQGIETIEGFQQMFVTKTLNTEDTDEVKILTIWESEDSFNNWLNSDVFKEAHKNVRLKSDDDGQQSPILSNKVFKYDIGYHYQK
>NZ_AP019751.1|WP_000723452.1|193597_194743_+|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)
MKKIMVIFGTRPEAIKMAPLVKEIDHNGNFEANIVITAQHRDMLDSVLSIFDIQADHDLNIMQDQQTLAGLTANALAKLDSIINEEQPDMILVHGDTTTTFVGSLAAFYHQIPVGHVEAGLRTHQKYSPFPEELNRVMVSNIAELNFAPTVIAAKNLLFENKDKERIFITGNTVIDALSTTVQNDFVSTIINKHKGKKVILLTAHRRENIGEPMHQIFKAVRDLADEYKDVVFIYPMHRNPKVRAIAEKYLSGRNRIELIEPLDAIEFHNFTNQSYLVLTDSGGIQEEAPTFGKPVLVLRNHTERPEGVEAGTSRVIGTDYDNIVRNVKQLIEDDEAYQRMSQANNPYGDGQASRRICEAIEYYFGLRTDKPDEFVPLRHK
>NZ_AP019751.1|WP_000779494.1|192258_193521_+|nucleotide-sugar-dehydrogenase
MKLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQSGQISIEEPGLQEIYEEVLSSGKLKVSTTPEASDVFIIAVPTPNNDDQYRSCDISLVMRALDSILPFLKKGNTIIVESTIAPKTMDDFVKPVIENLGFTIGEDIYLVHCPERVLPGKILEELVHNNRIIGGVTKACIEAGKRVYRTFVQGEMIETDARTAEMSKLMENTYRDVNIALANELTKICNNLNINVLDVIEMANKHPRVNIHQPGPGVGGHCLAVDPYFIIAKDPENAKLIQTGREINNSMPAYVVDTTKQIIKALSGNKVTVFGLTYKGDVDDIRESPAFDIYELLNQEPDIEVCAYDPHVELDFVEHDMSHAVKDASLVLILSDHSEFKNLSDSHFDKMKHKVIFDTKNVVKSSFEDVSYYNYGNIFNFIDK
>NZ_AP019751.1|WP_001230681.1|191317_192205_+|capsular-polysaccharide-type-5/8-biosynthesis-epimerase-CapN
MRKNILITGVHGYIGNALKDKLIEQGHQVDQINVRNQLWKSTSFKDYDVLIHTAALVHNNSPQARLSDYMQVNMLLTKQLAQKAKSEDVKQFIFMSTMAVYGKEGQVGKSDQIDTQTPMNPTTNYGISKKFAEQALQELISDSFKVAIVRPPMIYGAHCPGNFQRLMQLSKRLPIIPNINNQRSALYIKHLTAFIDQLISLEVTGVYHPQDSFYFDTSSVMYEIRRQSHRKTVLINMPSVLNKYFNKLSVFRKLFGNLIYSNTLYENNNALEVIPGKMSLVIADIMDETTTKDKA
>NZ_AP019751.1|WP_000825101.1|190760_191318_+|sugar-transferase
MKRLFDVVSSIYGLVVLSPILLITALLIKMESPGPAIFKQKRPTINNELFNIYKFRSMKIDTPNVATDLMDSTSYITKTGKVIRKTSIDELPQLLNVLKGEMSIVGPRPALYNQYELIEKRTKVNVHTIRPGVTGLAQVMGRDDITDDQKVAYDHYYLTHQSMMLDMYIIYKTIKNIVTSEGVHH
>NZ_AP019751.1|WP_001291010.1|189544_190750_+|glycosyltransferase-family-4-protein
MSEKKILILCQYFYPEYVSSATLPTQLAEDLIANHINVDVMCGWPYEYSNHKQVSKTEMHRGICIRRLKYSRFNNKSKVGRIINFFSLFSKFVINIPKMLKYDQILVYSNPPILPLIPDVLHRLLKKKYSFVVYDIAPDNAIKTGATRPGSMIDKLMRYINRHVYKNAENVIVLGTEMKNYLLNHQISKNADNIHVIPNWYDMRQLQDNRIYNDTFKAYREQYDKILLYSGNMGQLQDMETLISFLKLNKDQPQTLTILCGHGKKFADVKTAIEDHRIENVKMFEFLTGTDYADVLKIADVCIASLIKEGVGLGVPSKNYGYLAAKKALVLIMDKQSDIVQHVEQYDAGIQIDNGDAHAIYNFINTHSSKELHEMGERAHQLFKDKYTREINTMKYYNLLK
>NZ_AP019751.1|WP_001238807.1|188272_189511_+|oligosaccharide-flippase-family-protein
MRLNKFIGDSFLMILSSGIAQVILIITTPIITRLYSPTEFGEFTIFSNIAMILIPIINARYDLLIVNTKNDRSANILSQISFLISLLILLILIPIFAISACLYPNFILDFIFIIIMLFLVSLTNIFTNYLNKERKYKVLSLINVFRAGSMALLQIIFGLLALGSLGLIIGFSLSYIAGITLGYKTFKKHFNIVRDKEETKALFLENKNQLVYSTPSILLNSLSFSVVVFFIGILYTNTEVGIYGMAIRVLGIPVTIISLGLSKIFMQQANDYYIEHGNFRNLLLKFSSILVIVSIILYVPLYLFSEELVNILLGHSWVDAITVIKIVIPLFVIRLIVSTVSLSVIVLQKQQLELILQALFLIGTTATFVISKMLNLTFLNFVSINTIVLIVSYMIFFIALYYFAKNKQFKNS
>NZ_AP019751.1|WP_000356963.1|199337_199541_-|hypothetical-protein
MDKESVVASLARNKKIAVETMAGQRYIIERILHTNDEKHIHILKPKDVVLDVDSIKEIDENHLNDAT
>NZ_AP019751.1|WP_000171919.1|199718_200231_+|DUF4242-domain-containing-protein
MTLFLLEANNLDFASTKEELEAKAASLSTKTIPTLIEVQATENLTHGYFIVEANDEAEAKQFLTEADISIQLVKEVRLVGKDLDEVKNGDAHVDYLVTWNIPEGITMDQYLARKKKNSVHYEEVPEVEFKRTYVCEDMSKCICLYNAPDEEAVRRARKAVDTPIDGIEKL
>NZ_AP019751.1|WP_000590847.1|200572_201313_+|ABC-transporter-ATP-binding-protein
MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLMLFQHHNLLPWKTINDNIRIGFRQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLQDQLVQLKHKTQSTIILVTHDIDEAIYLSDRIVLLGEGCNIISQYEITASHPRSRNDSHLLKVRNEIMETFALNHHQVEPEYYL
>NZ_AP019751.1|WP_000826671.1|201326_202301_+|ABC-transporter-substrate-binding-protein
MKRLSIIVIIGIFIITGCDWQRTSKEPSKNAQNQQVIKIGYLPITHSANLMMTKKLLSQYNHPKYKLELVKFNNWPDLMDALNSGRIDGASTLIELAMKSKQKGSNIKAVALGHHEGNVIMGQKGMHLNEFNNNGDDYHFGIPHRYSTHYLLLEELRKQLKIKPGHFSYHEMSPAEMPAALSEHRITGYSVAEPFGALGEKLGKGKTLKHGDDVIPDAYCCVLVLRGELLDQHKDVAQAFVQDYKKSGFKMNDRKQSVDIMTHHFKQSRDVLTQSAAWTSYGDLTIKPSGYQEITTLVKQHHLFNPPAYDDFVEPSLYKEASRS
>NZ_AP019751.1|WP_000197961.1|202297_203059_+|ABC-transporter-permease
MTRPTNNKFILPIITFIIFLGIWEMVIIIGHYQPVLLPGPALVGKSIWTFIVTGEIFQHLAISLWRFVAGFVVALLVAIPLGFLLGRNRWLYNAIEPLFQLIRPISPIAWAPFVVLWFGIGSLPAIAIIFIAAFFPIVFNTIKGVRDIEPQYLKIAANLNLTGWSLYRNILFPGAFKQIMAGIHMAVGTSWIFLVSGEMIGAQSGLGFLIVDARNMLNLEDVLAAIFFIGLFGFIIDRFISYIEQFILRRFGE
>NZ_AP019751.1|WP_000171644.1|203071_204103_+|acyl-CoA/acyl-ACP-dehydrogenase
MTLETLIKEQLDPHLVEVDEGTYYPRTFIQQLFVDGYFGEAALRKNAEVIEAVSQSCLTTGFCLWCQLAFSTYLENATQPHLNNDLQQQLLSGEILGATGLSNPMKSFNDLEKLNLEHTYVDGQLVVSGRMPAVSNIQEDHYFGAISKHESSDEFVMFILRANQDGITLVEKTNFLGVNGSATYQITLNQVVVPQSQIITHDAKQFAATIRPQFIAYQIPIGLGSIKSSLELIDAFSNAQNGINQYLEYDVEAFKKRYRQLREEYYAILDDGNLTSHLNELISLKKDIGYLLLDVNQASVVNGGSRAYTPYSPQVRKLKEGFFFAALTPTLRHLGKLEAELKG
>NZ_AP019751.1|WP_001092004.1|204319_204679_+|DUF2294-domain-containing-protein
MNTIDTHTKEQQFSNLVRSYRKEYVGKGPNSIRVSFKDNWAIAHMTGVLSKVESFYLNDKRNESMLHYTRTEKIKQMYKEIDVNEMESLVGAKFVKLFTDIDLNDDEVISIFVFDKSIE
>NZ_AP019751.1|WP_000706137.1|204852_205878_+|NAD-dependent-formate-dehydrogenase
MKIVALFPEAVEGQENQLLNTKKALGLKTFLEERGHEFIILADNGEDLDKHLPDMDVIISAPFYPAYMTRERIEKAPNLKLAITAGVGSDHVDLAAASEHNIGVVEVTGSNTVSVAEHAVMDLLILLRNYEEGHRQSVEGEWNLSQVGNHAHELQHKTIGIFGFGRIGQLVAERLAPFNVTLQHYDPINQQDHKLSKFVSFDELVSTSDAITIHAPLTPETDNLFDKDVLSRMKKHSYLVNTARGKIVNRDALVEALASEHLQGYAGDVWYPQPAPADHPWRTMPRNAMTVHYSGMTLEAQKRIEDGVKDILERFFNHEPFQDKDIIVASGRIASKSYTAK
>NZ_AP019751.1|WP_000826862.1|206263_207514_+|MFS-transporter
MKRLSTTLKVRLISNFLQLIITTAFIPFIALYLTDMLSQSIVGIYLVGLVVLKFPLSIISGYLIEIFPKKLLVLIYQATMVIMLVFMGVFGSHQLWQIIGFCVAYAIFTIVWGLQFPVMDTLIMDAITEDVEHYIYKISYWMTNLSVAIGALLGGLMYGYSMLLLFLIAACIFLIVLFILYIWLPQDRNQVKQSDDKRHASRYQKLQIMNIFRSYKLVLKDRNYMLLISGFSIIMMGEFSISSYIAIRLKDQFETISIGSYDITGAKMLAILLMINTVVVILLTYSISKVVLKIDFKKALITGLLIYIVGYSGLTYLNQFGLLVVFMIIATVGEIIYSPIVSEQRFKIIPKAKRGTYSAVNALGIHFSETLARLGIVLGVFLTSLQMGLYMFIVLTIGASMLVAGVFGGQKQVNTN
>NZ_AP019751.1|WP_000605278.1|207960_215136_+|amino-acid-adenylation-domain-containing-protein
MIMGNLRFQQEYFRIYKNNTESTTHRNAYWVKLAKNVEATKMMYALSTIVQQHASIRHFFDVTTDDNLTMILHEFLPFIEIKQVPSSSANYDLEAFFKQELSTYHFNDSPLFKVKLFQFADAAYILLDFHVSIFDDSQIDIFLDDLCNAYRGNTVINNTRQHAHINRNDDKDNQDASHIALDSNYFRLENNSDIHIDSYFPIKHPFEQALYQTYLIDDMTSIDMASLAVSVYLANHIMSQQHDVTLGIHVPSHLPNDLHGNIVPLTLTIDAKDVCQRFTTDFNKCVLQNMSQLQCAKSSLSLETIFHCYHHMMSCCNDVIEDVHQIHDAHTSLADIEIFPHQHGFKIIYNSAAYDLLSIETLSDLVRNIYLQITEENGNKRTTVDELNLMTERDIQLYDDINLSLPEIDDAQTVVTLFEQQVEATPNHVAVQFDGVFITYQTLNARANDLAHRLRNQYGVEPNDRVAVIAEKSIEMIIAMIGVLKAGGAYVPIDLNYPSDRQEYILKDVTPKVVITYQALYENGKQNINHIDLNKIAWKNIDNLSKCNTLEDHAYVIYTSGTTGNPKGTLIPHRGIVRLVHQNHYVPLNEETTILLSGTIAFDAATFEIYGALLNGGKLIVAKKEQLLNPIAVEQLINENDVNTMWLTSSLFNQIASERIEVLVPLKYLLIGGEVLNAKWVDLLNQKPKHPQIINGYGPTENTTFTTTYNIPNKVPNRIPIGKPILGTHVYIMQGERRCGVGIPGELCTSGFGLAAGYLNQPELTADKFIKDSNINQLMYRSGDIVRLLPDGNIDYLYRKDKQVKIRGFRIELSEVEHALERIQGINKAVVIVQNHDQDQYIVAYYEAMHTLSHNKIKSQLRMTLPEYMIPVNFMHIEQIPITINGKLDKKALPIMDYVDTDAYVAPSTDTEHLLCQIFADILHVNQVGIHDNFFELGGHSLKATLVVNRIEASTGKRLQIGDLLQKPTVFELAQAIAKVQEQNYEVIPETIVKDDYVLSSAQKRMYLLWKSNHKDTVYNVPFLWRLSSELNVAQLRQAVQRLIARHEILRTQYIVVDDEVRQRIVADVAVDFEEVNTHFTDEQEIMRQFVAPFNLEKPSQIRVRYIRSPLHAYLFIDTHHIINDGMSNIQLMNDLNALYQHKLLLPLKLQYKDYSEWMSHRDMTKHRQYWLSQFKDEVPILSLPTDYVRPNIKTTNGAMMSFTMNQQMRQLLQKYVEKHQITDFMFFMSVVMTLLSRYARKDDVVVGSVMSARMHKGTEQMLGMFANTLVYRGQPSPDKMWTQFLQEVKEMSLEAYEHQEYPFECLVNDLDQSHDASRNPLFDVMLVLQNNETNHAHFGHSKLTHIQPKSVTAKFDLSFIIEEDRDDYTINIEYNTDLYHSETVRHMGNQCMIMIDYILKHQDTLQICDIPNGTEELLNWVNTHVNDRMLNVPGNKSIISYFNEVVSRQGNHVALVMNDLTMTYETLRNYVDAIAHMLLSNGVGNGQRVALFTERSFEMIAAMLATVKVGASYIPIDIDFPNKRQGAILEDAKVTAVMSYGVEIETTLPVIQLENAKGFVESKENEQYDDLHGNQLENTAMLDNEMYAIYTSGTTGMPKGVAIRQRNLLNLVHAWSTELQLGDNEVFLQHANIVFDASVMEIYCCLLNGHTLVIPDREERVNPEQLQQLINKHRVTVASIPLQMCSVMEDFYIEKLITGGATSTASFVKYIEKHCGTYFNAYGPSESTVITSYWSHQCGDLIPETIPIGKPLSNIQVYIMSDGLLCGIGMPGELCIAGDSLAIGYINRPELMADKWQNNPFGKGKLYHSGDLARYTSDGQIEFLGRIDKQVKVNGYRIELDEIENAILAIRGISDCVVTVSHFDTHDILNAYYVGEQQMEQDLKQYLNDHLPKYMIPKTITHIDYMPLTTNDKVDTTRLPNPSTIQQSNKVYSEPSNEIEQTFVDVFGEVLKQNDVGVDDDFFELGGNSLEAMLVVSHLKRFGHHISMQTLYQYKTVRQIVNYMHQNQQSLVALPDNLSELQKIVMSRYNLGVLEDSLSHRPIGNTLLTGATGFLGAYLIEALQGYSHRIYCFIRADNEEIARYKLMTNLNDYFSEETVEMMLSNIEVIVGDFECMDDVVLPENMDTIIHAGARTDHFGDDDEFEKVNVQGTVDVIRLAQQHHARLIYVSTISVGTYFDIDTEDVTFSEADVYKGQLLTSPYTRSKFYSELKVLEAVNNGLDGRIVRVGNLTSPYNGRWHMRNIKTNRFSMVMNDLLQLDCIGVSMAEMPVDFSFVDTTARQIVALAQVNTPQIIYHVLSPNKMPVKSLLECVKRKEIELVSDESFNEILQKQDMYETIGLTSVDREQQLAMIDTTLTLKIMNHISEKWPTITNNWLYHWAQYIKTIFNK

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Crispr_ID: NZ_AP019751_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019751_2

322477-322667

Orphan

Consensus_repeat	Method
GTGCAAGTTGGCGGGGCCCCAACA	CRT

3 spacers

The CRISPR arrays of NZ_AP019751_2

>merge|NZ_AP019751|2|322477-322667|CRT
GTGTTATATTGGCGGGCCCCAACATAGAAGCTGGCGGAAAGTCAGCATACAATAATGTGCAAGTTGGCGGGGCCCCAACACAGAGAATTTCGAAAAGAAATTCTACAGGCAATGCAAGTTGGCGGGGCCCCAACATAGAAGCTGGCGGAAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACA

>NZ_AP019751|2|1|322477-322667|CRT
GTGTTATATTGGCGGGCCCCAACA	TAGAAGCTGGCGGAAAGTCAGCATACAATAAT
GTGCAAGTTGGCGGGGCCCCAACA	CAGAGAATTTCGAAAAGAAATTCTACAGGCA
ATGCAAGTTGGCGGGGCCCCAACA	TAGAAGCTGGCGGAAAGTCAGCTTACAATAAT
GTGCAAGTTGGCGGGGCCCCAACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019751.1\|WP_000975365.1\|312678_314400_+\|poly(ribitol-phosphate)-beta-N-acetylglucosaminyltransferase	unknown	unknown	gnl\|CDD\|376098
NZ_AP019751.1\|WP_000029204.1\|325333_326215_-\|ribose-transporter-RbsU	unknown	unknown	gnl\|CDD\|284268
NZ_AP019751.1\|WP_000164010.1\|320976_322413_+\|6-phospho-beta-glucosidase	unknown	unknown	gnl\|CDD\|181973
NZ_AP019751.1\|WP_001793213.1\|318071_318515_+\|antiholin-like-murein-hydrolase-modulator-LrgA	unknown	unknown	gnl\|CDD\|235222
NZ_AP019751.1\|WP_000645456.1\|317218_317959_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|184495
NZ_AP019751.1\|WP_000950281.1\|315461_317216_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225814
NZ_AP019751.1\|WP_000607067.1\|318507_319209_+\|antiholin-like-protein-LrgB	unknown	unknown	gnl\|CDD\|179810
NZ_AP019751.1\|WP_000608831.1\|314543_315218_+\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	unknown	unknown	gnl\|CDD\|183940
NZ_AP019751.1\|WP_144078888.1\|328345_329722_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_AP019751.1\|WP_000337383.1\|329955_330948_+\|linear-amide-C-N-hydrolase	unknown	unknown	gnl\|CDD\|225591
NZ_AP019751.1\|WP_000240920.1\|310957_312646_+\|CDP-glycerol-glycerophosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|367953
NZ_AP019751.1\|WP_000922317.1\|319316_320021_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_AP019751.1\|WP_000066930.1\|320169_320961_+\|PTS-glucose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225101
NZ_AP019751.1\|WP_000736792.1\|331273_332224_+\|glycine-glycine-endopeptidase-LytM	unknown	unknown	gnl\|CDD\|226451
NZ_AP019751.1\|WP_144078887.1\|326446_327445_-\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|224525
NZ_AP019751.1\|WP_001159765.1\|327825_328218_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_000182738.1\|323972_324887_-\|ribokinase	unknown	unknown	gnl\|CDD\|274000
NZ_AP019751.1\|WP_000747873.1\|324914_325319_-\|D-ribose-pyranase	unknown	unknown	gnl\|CDD\|183318
NZ_AP019751.1\|WP_000031274.1\|322960_323722_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_AP019751.1\|WP_001789860.1\|323740_323875_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_AP019751.1\|WP_000975365.1\|312678_314400_+\|poly(ribitol-phosphate)-beta-N-acetylglucosaminyltransferase	gnl\|CDD\|376098	pfam18674, TarS_C1, TarS beta-glycosyltransferase C-terminal domain 1. Beta-glycosyltransferase TarS is an enzyme responsible for the glycosylation of wall teichoic acid polymers of the S. aureus cell wall, a process that has been shown to be specifically responsible for methicillin resistance in MRSA. It contains a trimerization domain composed of tandem carbohydrate binding motifs.The two C-terminally localized regions composed of a series of beta-sheets participate in an extensive trimerization interface and they assume an immunoglobulin-like fold. It is suggested that both carbohydrate binding domains may be involved in polyRboP binding, however unlike pullulanase, the CBMs of TarS are involved in the formation of an extensive trimerization interface.	6.64158e-35
NZ_AP019751.1\|WP_000029204.1\|325333_326215_-\|ribose-transporter-RbsU	gnl\|CDD\|284268	pfam06800, Sugar_transport, Sugar transport protein. This is a family of bacterial sugar transporters approximately 300 residues long. Members include glucose uptake proteins, ribose transport proteins, and several putative and hypothetical membrane proteins probably involved in sugar transport across bacterial membranes. These members are transmembrane proteins which are usually 5+5 duplications. This model recognizes a set of five TMs,.	4.46997e-117
NZ_AP019751.1\|WP_000164010.1\|320976_322413_+\|6-phospho-beta-glucosidase	gnl\|CDD\|181973	PRK09589, celA, 6-phospho-beta-glucosidase; Reviewed.	0
NZ_AP019751.1\|WP_001793213.1\|318071_318515_+\|antiholin-like-murein-hydrolase-modulator-LrgA	gnl\|CDD\|235222	PRK04125, PRK04125, antiholin-like protein LrgA.	4.17541e-63
NZ_AP019751.1\|WP_000645456.1\|317218_317959_+\|DNA-binding-response-regulator	gnl\|CDD\|184495	PRK14084, PRK14084, DNA-binding response regulator.	4.37999e-152
NZ_AP019751.1\|WP_000950281.1\|315461_317216_+\|sensor-histidine-kinase	gnl\|CDD\|225814	COG3275, LytS, Putative regulator of cell autolysis [Signal transduction mechanisms].	0
NZ_AP019751.1\|WP_000607067.1\|318507_319209_+\|antiholin-like-protein-LrgB	gnl\|CDD\|179810	PRK04288, PRK04288, antiholin-like protein LrgB; Provisional.	5.86643e-124
NZ_AP019751.1\|WP_000608831.1\|314543_315218_+\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	gnl\|CDD\|183940	PRK13276, PRK13276, iron-sulfur cluster repair di-iron protein ScdA.	7.18502e-154
NZ_AP019751.1\|WP_144078888.1\|328345_329722_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.3192e-29
NZ_AP019751.1\|WP_000337383.1\|329955_330948_+\|linear-amide-C-N-hydrolase	gnl\|CDD\|225591	COG3049, COG3049, Penicillin V acylase and related amidases [Cell envelope biogenesis, outer membrane].	5.1195e-152
NZ_AP019751.1\|WP_000240920.1\|310957_312646_+\|CDP-glycerol-glycerophosphotransferase-family-protein	gnl\|CDD\|367953	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.	4.42901e-119
NZ_AP019751.1\|WP_000922317.1\|319316_320021_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	3.50966e-63
NZ_AP019751.1\|WP_000066930.1\|320169_320961_+\|PTS-glucose-transporter-subunit-IIA	gnl\|CDD\|225101	COG2190, NagE, Phosphotransferase system IIA components [Carbohydrate transport and metabolism].	3.3186e-53
NZ_AP019751.1\|WP_144078887.1\|326446_327445_-\|substrate-binding-domain-containing-protein	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	2.80631e-100
NZ_AP019751.1\|WP_000182738.1\|323972_324887_-\|ribokinase	gnl\|CDD\|274000	TIGR02152, Putative_ribokinase, ribokinase. This model describes ribokinase, an enzyme catalyzing the first step in ribose catabolism. The rbsK gene encoding ribokinase typically is found with ribose transport genes. Ribokinase belongs to the carbohydrate kinase pfkB family (pfam00294). In the wide gulf between the current trusted (360 bit) and noise (100 bit) cutoffs are a number of sequences, few of which are clustered with predicted ribose transport genes but many of which are currently annotated as if having ribokinase activity. Most likely some have this function and others do not. [Energy metabolism, Sugars].	4.25837e-143
NZ_AP019751.1\|WP_000747873.1\|324914_325319_-\|D-ribose-pyranase	gnl\|CDD\|183318	PRK11797, PRK11797, D-ribose pyranase; Provisional.	1.143e-69
NZ_AP019751.1\|WP_000031274.1\|322960_323722_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.48144e-27
NZ_AP019751.1\|WP_000736792.1\|331273_332224_+\|glycine-glycine-endopeptidase-LytM	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	6.59985e-33

>NZ_AP019751.1|WP_000164010.1|320976_322413_+|6-phospho-beta-glucosidase
MTKLPRNFMWGGALAANQFEGGYDKGGKGLSVIDVMTSGAHGKARQITKSIDQNHYYPNHEGIDFYHRYKEDIALFNEMGLKCLRTSIAWTRIFPNGDEDVPNEEGLAFYDRIFDELIAQDIEPVVTLSHFEMPLHLAKHYGGFRNREVVDYFVHFARVVFERYKDKVTYWMTFNEINNQMDTSNPIFLWTNSGVALTENDNPEEVLYQVAHHELLASALAVRLGKEINPKFKIGTMISHVPIYPYSCHPKDMMEAQIANRLRFFFPDVQVRGYYPSYAKKMLARKGYDVGWQEGDDSILQQGTVDYIGFSYYMSTAVKHDVDTTVENNIVNGGLNHSVENPHIATSDWGWAIDPDGLRYTLNVLYDRYQLPLFIVENGFGAVDEVVDGHIHDDYRIEYLKAHITAAIEAVDQDGVDLIGYTPWGIIDIVSFTTGEMKKRYGLIYVDRDNDGHGTMERLKKDSFYWYQQVIASNGDKL
>NZ_AP019751.1|WP_000066930.1|320169_320961_+|PTS-glucose-transporter-subunit-IIA
MSNKYKEQAQDILTAVGGVENIVDATYDTKCITIHMQHTIPSTANEVKQIVDVTSVAENDAQLVIKLNGNVDEVYQQLQRLIKNANVEESENTDNINSQDTSYIPQVKVTTPILVKAPIAGRRILLKEVRDSIFREKMVGEGLAIKAHEESKVIAPFNGLISMIVPTKHAVRIQSEDGVDIVIHIGVNTVDLEGKGFKCFVKQNDRVEAGQTLLQFDQQYIQQQGYNADVIVVISNSADLGKVELTMNEIITTEDVIFKIFKN
>NZ_AP019751.1|WP_000922317.1|319316_320021_-|GntR-family-transcriptional-regulator
MLKYEHIAKQLNAFIHQSKFKPGDKLPSVTQLKERYQVSKSTIIKALGLLEQDGLIYQAQGSGIYVRNIADANRINVFKTNGFSKSLGEHRMTSKVLVFKEMATPPKSVQDELQLNADDTVYYLERLRFVDDDVLCIEYSYYHKEIVKYLNDDIAKGSIFDYLESNMKLRIGFSDIFFNVDKLTSSEASLLQLSTGEPCLRYHQTFYTMTGKPFDSSDIVFHYRHAQFYIPSKK
>NZ_AP019751.1|WP_000607067.1|318507_319209_+|antiholin-like-protein-LrgB
MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSMVFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIGIGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILNGVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVGVVVVAVVPVFVAIFF
>NZ_AP019751.1|WP_001793213.1|318071_318515_+|antiholin-like-murein-hydrolase-modulator-LrgA
MVVKQQKDASKPAHFFHQVIVIALVLFVSKIIESFMPIPMPGSVIGLVLLFVLLCTGAVKLGEVEKVGTTLTNNIGLLFVPAGISVVNSLGVISQAPFLIIGLIIVSTILLLICTGYVTQIIMKVTSRSKGDKVTKKIKIEEAQAHD
>NZ_AP019751.1|WP_000645456.1|317218_317959_+|DNA-binding-response-regulator
MKALIIDDEPLARNELTYLLNEIGGFEEINEAENVKETLEALLINQYDIIFLDVNLMDENGIELGAKIQKMKEPPAIIFATAHDQYAVQAFELNATDYILKPFGQKRIEQAVNKVRATKAKDDNSASAIANDMSANFDQSLPVEIDDKIHMLKQQNIIGIGTHNGITTIHTTNHKYETTEPLNRYEKRLNPAYFIRIHRSYIINTKHIKEVQQWFNYTYMVILTNGVKMQVGRSFMKDFKASIGLL
>NZ_AP019751.1|WP_000950281.1|315461_317216_+|sensor-histidine-kinase
MLSLTMLLLERVGLIIILAYVLMNIPYFKNLMNRRRTWKARWQLCIIFSLFALMSNLTGIVIDHQHSLSGSVYFRLDDDVSLANTRVLTIGVAGLVGGPFVGLFVGVISGIFRVYMGGADAQVYLISSIFIGIIAGYFGLQAQRRKRYPSIAKSAMIGIVMEMIQMLSILTFSHDKAYAVDLISLIALPMIIVNSVGTAIFMSIIISTLKQEEQMKAVQTHDVLQLMNQTLPYFKEGLNRESAQQIAMIIKNLMKVSAVAITSKNEILSHVGAGSDHHIPTNEILTSLSKDVLKSGKLKEVHTKEEIGCSHPNCPLRAAIVIPLEMHGSIVGTLKMYFTNPNDLTFVERQLAEGLANIFSSQIELGEAETQSKLLKDAEIKSLQAQVSPHFFFNSINTISALVRINSEKARELLLELSYFFRANLQGSKQHTITLDKELSQVRAYLSLEQARYPGRFNININVEDKYRDVLVPPFLIQILVENAIKHAFTNRKQGNDIDVSVIKETATHVRIIVQDNGQGISKDKMHLLGETSVESESGTGSALENLNLRLKGLFGKSAALQFESTSSGTTFWCVLPYERQEEE
>NZ_AP019751.1|WP_000608831.1|314543_315218_+|iron-sulfur-cluster-repair-di-iron-protein-ScdA
MINKNDIVADVVTDYPKAADIFRSVGIDFCCGGQVSIEAASLEKKNVDLNELLQRLNDVEQTNTPGSLNPKFLNVSSLIQYIQAAYHEPLREEFKNLTPYVTKLSKVHGPNHPYLVELKETYDTFKNGMLEHMQKEDDVDFPKLIKYEQGEVVDDINTVIDDLVSDHIATGQLLVKMSDLTSSYEPPIEACGTWRLVYQRLKALEVLTHEHVHLENHVLFKKVS
>NZ_AP019751.1|WP_000975365.1|312678_314400_+|poly(ribitol-phosphate)-beta-N-acetylglucosaminyltransferase
MMKFSVIVPTYNSEKYITELLNSLAKQDFPKTEFEVVVVDDCSTDQTLQIVEKYRNKLNLKVSQLETNSGGPGKPRNVALKQAEGEFVLFVDSDDYINKETLKDAAAFIDEHHSDVLLIKMKGVNGRGVPQSMFKETAPEVTLLNSRIIYTLSPTKIYRTTLLKDNDIYFPEELKSAEDQLFTMKAYLNANRISVLSDKAYYYATKREGEHMSSAYVSPEDFYEVMRLIAVEILNADLEEAHKDQILAEFLNRHFSFSRTNGFSLKVKLEDQPQWINALGDFIQAVPERVDALVMSKLRPLLHYARAKDIDNYRTVEESYRQGQYYRFDIVDGKLNIQFNEGEPYFEGIDIAKPKVKMTAFKFDNHKIVTELTLNEFMIGEGHYDVRLKLHSRNKKHTMYVPLSVNANKQYRFNIMLEDIKAYLPKEKIWDVFLEVQIGTEVFEVRVGNQRNKYAYTAETSALIHLNNDFYRLTPYFTKDFNNISLYFTAITLTDSISLKLKGKNKIILTGLDRGYVFEEGMASVVLKDDMIMGMLSQTSENEVEILLSKDIKKRDFKNIVKLNTAHMTYSLK
>NZ_AP019751.1|WP_000240920.1|310957_312646_+|CDP-glycerol-glycerophosphotransferase-family-protein
MVKSKIYIDKIYWERVQLFVEGHSENLDLEDSNFVLRNLTETRTMKANDVKIDGNQFVCRFNVAILDNGYYLPEDKYLLVNEQELDYIAQLNPDVINDAYQNLKPEQEEEYNELETQNGKINFLLQTYLKEFRKGGISKKTVYTVTPEISSDVNEFVLDVVVTTPEVKSIYIVRKYKELRKYFRKQSFNTRQFIFKAIFNTTKFFHLKKGNTVLFTSDSRPTMSGNFEYIYNEMLRQNLDKKYDIHTVFKANITDRRGIIDKFRLPYLLGKADYIFVDDFHPLIYTVRFRRSQEVIQVWHAVGAFKTVGFSRTGKKGGPFIDSLNHRSYTKAYVSSETDIPFYAEAFGIKEKNVVPTGVPRTDVLFDEAYATQIKQEMEDELPIIKGKKVILFAPTFRGSGHGTAHYPFFKIDFERLARYCEKNNAVVLFKMHPFVKNRLNIADKHKQYFVDVSDFREVNDILFITDLLISDYSSLIYEYAVFKKPMIFYAFDLEDYITTRDFYEPYESFVPGKIVQSFDALMDALDNEDYEGEKVIPFLDKHFKYQDGRSSERLVRNLFGS
>NZ_AP019751.1|WP_000031274.1|322960_323722_-|class-I-SAM-dependent-methyltransferase
MSKEAGHTFLAKLGKTRLRPGGKEATDWLIQQGAFSQDKQVLEVACNMCTTSIYLAHTYGCHIQGVDINKKALEKAQENISAAGLESYIQVQQANAVKLPFDDNQFDIVLNEAMLTMLPITIKEKALREYYRVLKPGGILLTHDIVIVNESHATHVVKSLSAAINVNVSPQTKLGWLDLYNQAGFNHVHYHTGPMSLMTPKGLIYDEGIVGTIKIINNALKKENRPMFCKMFKTMTKLRKDMNYITFVAKKED
>NZ_AP019751.1|WP_001789860.1|323740_323875_+|hypothetical-protein
MIIIIINIAYLYAIIWKLKRLQKIVTSFITKHESTSIGLVENYF
>NZ_AP019751.1|WP_000182738.1|323972_324887_-|ribokinase
MTNKVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGANQAIATARMQADTTFITKIGTDGVADFILEDFKAAHIDTSYIIKSTEAKTGQAFITVNAEGQNTIYVYGGANMTMTPEDVINAKDAIINADFVVAQLEVPIPAIISAFEIAKAHGVTTVLNPAPAKALPNELLSLIDIIVPNETEAELLSGIKVTNEQSMKDNANYFLSLGIKTVLITLGKQGTYFATKNQSQHIEAYKVNAIDTTAAGDTFIGAFVSRLNKSQDNLADAIDFGNKASSLTVQKHGAQASIPLLEEVNQV
>NZ_AP019751.1|WP_000747873.1|324914_325319_-|D-ribose-pyranase
MKKSAVLNEHISKAIATIGHFDLLTINDAGMPIPNDHRRIDLAVTKNLPRFIDVLATVLEEMEIQKIYLAEEIKEHNPTQLQQIKQLISSEIEIIFIPHEEMKSNLAHPLNKGNIRTGETTPYSNIALESNVTF
>NZ_AP019751.1|WP_000029204.1|325333_326215_-|ribose-transporter-RbsU
MSIVALLIGLGPLIGWGFFPTVASKFGGKPVHQIIGATVGTLIFAIILAVVTSSGFPTGTNLLFALLSGAGWGFGQIITFKAFELVGSSRAMPVTTAFQLLGASLWGVFALGNWPGIGHKIIGFTALVVILIGARMTVWSERKEASNAKNLRRAVVLLLIGEFGYWLYSAAPQATSIDGLTAFLPQAMGMVIVAVIYGFMNMKAENPFRNKITWLQIISGFFFAFGALTYLISAQPNMNGLATGFILSQTSVVLATLTGIYFLKQHKTSKEMVITIIGLVLILVAASVTVFIK
>NZ_AP019751.1|WP_144078887.1|326446_327445_-|substrate-binding-domain-containing-protein
MKKVSIKDVAREAGVSVTTVSHILNHNDSRFSATTIKNVHAVSERLGYAPNKHAKQLRGSKIQTIGVILPSLTNPFFSALMQSIHDHKPSDVDLCFLTSTATDLYDNIKHLIDRGIDGLIIAQYISSPDALNNYLKKHHVPYVVLDQNDHQGYTDFVRTNEYQGGQLAAQHLIELGHNNMVIVAPYDMMANMSTRVAGFVDTLRANQLPEPQIVHTELSKRGGLTIVDDIMVQSATAIFAINDELAIGILRGLIEHGISIPKDISLIGYDDIDYAAYVSPPLTTVAQPITDIGKTSLTLLLQRLQHLDKSIDMIELPTTLKIRATTGYHLSN
>NZ_AP019751.1|WP_001159765.1|327825_328218_+|hypothetical-protein
MQFKLKEEEIISFLELKYPEKEFEYGRLLVGQHKRDDLDVYYFGDTFLMCTIISFKTFEIKETVELSYDAVNRIVLKDGWLFRKMRIETMQKVLKYGTSKLMLTDFQKENYNKYIQGQKQRVIFENGHFV
>NZ_AP019751.1|WP_144078888.1|328345_329722_-|MFS-transporter
MNNTQSSPRSNIIIAIMLSALTYWLFAQSFINIGPLVGQTYQTSPAVLNLSISLTSFATGIFMVAAGDIADKIGQLRMTYMGLIISMFASLLLIISDITALLIIGRILQGLSAAILLPSTVGVLNNQFKGEHLRRAISYLMISTVGGIGLAGVIGGLIATNFGWQTNFIISIVIAFIAILLLKGTPEKVSQHSHRHPFDYKGMSIFAVMIGSFTLLLTQGFEQGWFSTFSFICLSIFIITTLIFIIIERRHEVPFIDFSVLRNRPFIGAFLNNFVLNSGLGVTVVFFIYAQTHLGLLAAQSGLVTLPYAIVAVAMIRLGEKATLRFGGKLMLIIGPLFPVIGITIISMTQLSASQYVIAVIIGFVICAIGNGLVATPGLTIAIFSMPNEKVGLATGLYKMSGTLGGAFGIALSTTVFSMLQLNYAPSVAATVTFIVSIVLMILGSLSAYMIIPKTVKS
>NZ_AP019751.1|WP_000337383.1|329955_330948_+|linear-amide-C-N-hydrolase
MCTGFTIQTLNNQVLLGRTMDYDYPLDGSPAVTPRNYRWTSRTGTTGQTQYGFIGTGTDMEGFIYGDGVNEHGVAISTQYFRGYSSYGSTHKAGAMNITQNEIVTWILGYTTSIEDMKQQASQIHVVAVYLNDIGEVPPLHYHVSDATGHSVEVSFKEGEVVIKDNPIGVLTNHPDLDWHYSNLRQYINISPYPATAKLLEGVTIEPLGNEAGTFGLPGGFTSTERFVRMAFMKANIAQNNDKEMDLMNAFYLLDAVNIPIGIVRPHDADNHYTMYQTVINLTTRTLYIKYYGSNELVALKLTDDLINRKDMTIFKPEKHITIRKLNDNQ
>NZ_AP019751.1|WP_000736792.1|331273_332224_+|glycine-glycine-endopeptidase-LytM
MKKLTAAAIATMGFATFTMAHQADAAETTNTQQAHTQMSTQSQDVSYGTYYTIDSNGDYHHTPDGNWNQAMFDNKEYSYTFVDAQGHTHYFYNCYPKNANANGSGQTYVNPAIAGDNNDYTASQSQQHINQYGYQSNVGPDASYYSHSNNNQAYNSHDGNGKVNYPNGTSNQNGGLASKATASGHAKDASWLTSRKQLQPYGQYHGGGAHYGVDYAMPENSPVYSLTDGTVVQAGWSNYGGGNQVTIKEANSNNYQWYMHNNRLTVSAGDKVKAGDQIAYSGSTGNSTAPHVHFQRMSGGIGNQYAVDPTSYLQSR

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Crispr_ID: NZ_AP019751_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019751_3

889435-889515

Unclear

Consensus_repeat	Method
TTCTTTATGTTGGGGCCCCGCCAACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP019751_3

>merge|NZ_AP019751|3|889435-889515|CRISPRCasFinder
TTCTTTATGTTGGGGCCCCGCCAACTTGCATTGTTTGTAGAATTTCTTTTCGAAATTCTTTATGTTGGGGCCCCGCCAACT

>NZ_AP019751|3|2|889435-889515|CRISPRCasFinder
TTCTTTATGTTGGGGCCCCGCCAACT	TGCATTGTTTGTAGAATTTCTTTTCGAAA
TTCTTTATGTTGGGGCCCCGCCAACT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019751.1\|WP_010956549.1\|880621_881732_+\|peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
NZ_AP019751.1\|WP_000617735.1\|876789_877362_+\|ribosome-associated-translation-inhibitor-RaiA	unknown	unknown	gnl\|CDD\|224461
NZ_AP019751.1\|WP_144078936.1\|895235_896147_+\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|224574
NZ_AP019751.1\|WP_000006551.1\|897249_898194_+\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NZ_AP019751.1\|WP_000958224.1\|889751_890684_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
NZ_AP019751.1\|WP_001049165.1\|898766_899354_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
NZ_AP019751.1\|WP_000229237.1\|884305_886291_+\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
NZ_AP019751.1\|WP_000506531.1\|877775_880307_+\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
NZ_AP019751.1\|WP_001790092.1\|880348_880453_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_001224793.1\|891536_892022_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_AP019751.1\|WP_000513312.1\|890689_891529_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
NZ_AP019751.1\|WP_000638419.1\|883800_884037_+\|CsbA-family-protein	unknown	unknown	gnl\|CDD\|227234
NZ_AP019751.1\|WP_144078934.1\|886298_889145_+\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_AP019751.1\|WP_144078935.1\|892029_893469_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
NZ_AP019751.1\|WP_000753321.1\|882140_882980_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_AP019751.1\|WP_000134963.1\|893535_894471_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NZ_AP019751.1\|WP_072360986.1\|881885_881993_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_000538141.1\|883153_883804_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|378993
NZ_AP019751.1\|WP_000816305.1\|899596_900499_-\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|224015
NZ_AP019751.1\|WP_001248939.1\|896143_897139_+\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689

Protein	Function_ID	Function_description	E-value
NZ_AP019751.1\|WP_010956549.1\|880621_881732_+\|peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
NZ_AP019751.1\|WP_000617735.1\|876789_877362_+\|ribosome-associated-translation-inhibitor-RaiA	gnl\|CDD\|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	1.13584e-37
NZ_AP019751.1\|WP_000006551.1\|897249_898194_+\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
NZ_AP019751.1\|WP_000958224.1\|889751_890684_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
NZ_AP019751.1\|WP_001049165.1\|898766_899354_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
NZ_AP019751.1\|WP_000229237.1\|884305_886291_+\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_AP019751.1\|WP_000506531.1\|877775_880307_+\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NZ_AP019751.1\|WP_000134963.1\|893535_894471_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
NZ_AP019751.1\|WP_001224793.1\|891536_892022_+\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
NZ_AP019751.1\|WP_000513312.1\|890689_891529_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	4.82832e-120
NZ_AP019751.1\|WP_000638419.1\|883800_884037_+\|CsbA-family-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
NZ_AP019751.1\|WP_144078934.1\|886298_889145_+\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_AP019751.1\|WP_144078935.1\|892029_893469_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.17824e-06
NZ_AP019751.1\|WP_000753321.1\|882140_882980_+\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.82721e-42
NZ_AP019751.1\|WP_144078936.1\|895235_896147_+\|RNase-adapter-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	1.07067e-168
NZ_AP019751.1\|WP_000538141.1\|883153_883804_+\|HD-domain-containing-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
NZ_AP019751.1\|WP_000816305.1\|899596_900499_-\|TIGR01777-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	1.79553e-154
NZ_AP019751.1\|WP_001248939.1\|896143_897139_+\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172

>NZ_AP019751.1|WP_144078934.1|886298_889145_+|excinuclease-ABC-subunit-UvrA
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEFYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>NZ_AP019751.1|WP_000229237.1|884305_886291_+|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIEEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>NZ_AP019751.1|WP_000638419.1|883800_884037_+|CsbA-family-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>NZ_AP019751.1|WP_000538141.1|883153_883804_+|HD-domain-containing-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>NZ_AP019751.1|WP_000753321.1|882140_882980_+|CHAP-domain-containing-protein
MKKTLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKTPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>NZ_AP019751.1|WP_072360986.1|881885_881993_+|hypothetical-protein
MYLLKQHMQCAFSNITYGDFQGIELIVENVLNYMV
>NZ_AP019751.1|WP_010956549.1|880621_881732_+|peptide-chain-release-factor-2
MELSEIKRNIDKYNQDLTQIRGSLDLENKETNIQEYEEMMAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
>NZ_AP019751.1|WP_001790092.1|880348_880453_+|hypothetical-protein
MLWEESFYFTSVKYFKKCEEVVKRCYVLSFKKSV
>NZ_AP019751.1|WP_000506531.1|877775_880307_+|preprotein-translocase-subunit-SecA
MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
>NZ_AP019751.1|WP_000617735.1|876789_877362_+|ribosome-associated-translation-inhibitor-RaiA
MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ
>NZ_AP019751.1|WP_000958224.1|889751_890684_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>NZ_AP019751.1|WP_000513312.1|890689_891529_+|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYVENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEKLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>NZ_AP019751.1|WP_001224793.1|891536_892022_+|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>NZ_AP019751.1|WP_144078935.1|892029_893469_+|tetratricopeptide-repeat-protein
MAQKNNNVIPMNFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>NZ_AP019751.1|WP_000134963.1|893535_894471_+|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>NZ_AP019751.1|WP_144078936.1|895235_896147_+|RNase-adapter-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNFYVHHRDAHIESGEKK
>NZ_AP019751.1|WP_001248939.1|896143_897139_+|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>NZ_AP019751.1|WP_000006551.1|897249_898194_+|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>NZ_AP019751.1|WP_001049165.1|898766_899354_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>NZ_AP019751.1|WP_000816305.1|899596_900499_-|TIGR01777-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKVLFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGMILSNEGGALQTMKLPYKYYIGGRLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE

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Crispr_ID: NZ_AP019751_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019751_4

936938-937019

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP019751_4

>merge|NZ_AP019751|4|936938-937019|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGAGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>NZ_AP019751|4|3|936938-937019|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGAGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019751.1\|WP_000255544.1\|930695_931313_-\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
NZ_AP019751.1\|WP_000571218.1\|938499_939525_+\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NZ_AP019751.1\|WP_000932228.1\|935955_936834_+\|DUF1963-domain-containing-protein	unknown	unknown	gnl\|CDD\|226395
NZ_AP019751.1\|WP_001147953.1\|934418_934739_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_AP019751.1\|WP_001006454.1\|945283_946534_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NZ_AP019751.1\|WP_000752917.1\|941405_941600_+\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_AP019751.1\|WP_000974464.1\|932360_932783_-\|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
NZ_AP019751.1\|WP_001065801.1\|937953_938250_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_AP019751.1\|WP_001018962.1\|937574_937961_+\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
NZ_AP019751.1\|WP_000290489.1\|935396_935777_+\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_AP019751.1\|WP_144078939.1\|943870_945178_+\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NZ_AP019751.1\|WP_000150012.1\|932930_933647_+\|type-I-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
NZ_AP019751.1\|WP_000732326.1\|940230_941052_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_AP019751.1\|WP_001183858.1\|941832_942684_-\|DUF368-domain-containing-protein	unknown	unknown	gnl\|CDD\|224946
NZ_AP019751.1\|WP_001140696.1\|930041_930623_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NZ_AP019751.1\|WP_000168845.1\|943011_943773_+\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NZ_AP019751.1\|WP_000589549.1\|934882_935239_+\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
NZ_AP019751.1\|WP_000422910.1\|933729_934269_+\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
NZ_AP019751.1\|WP_000569884.1\|931467_931962_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
NZ_AP019751.1\|WP_000520233.1\|939517_940213_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922

Protein	Function_ID	Function_description	E-value
NZ_AP019751.1\|WP_000255544.1\|930695_931313_-\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	1.6558e-60
NZ_AP019751.1\|WP_000571218.1\|938499_939525_+\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	3.37873e-170
NZ_AP019751.1\|WP_000932228.1\|935955_936834_+\|DUF1963-domain-containing-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	5.66518e-74
NZ_AP019751.1\|WP_001147953.1\|934418_934739_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.31384e-24
NZ_AP019751.1\|WP_001006454.1\|945283_946534_+\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_AP019751.1\|WP_000752917.1\|941405_941600_+\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.95583e-07
NZ_AP019751.1\|WP_000974464.1\|932360_932783_-\|organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	1.70812e-60
NZ_AP019751.1\|WP_001065801.1\|937953_938250_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
NZ_AP019751.1\|WP_001018962.1\|937574_937961_+\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
NZ_AP019751.1\|WP_000290489.1\|935396_935777_+\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	2.95269e-69
NZ_AP019751.1\|WP_144078939.1\|943870_945178_+\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	5.99538e-136
NZ_AP019751.1\|WP_000150012.1\|932930_933647_+\|type-I-3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	1.05028e-146
NZ_AP019751.1\|WP_000732326.1\|940230_941052_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	2.15951e-112
NZ_AP019751.1\|WP_001183858.1\|941832_942684_-\|DUF368-domain-containing-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	4.58436e-76
NZ_AP019751.1\|WP_001140696.1\|930041_930623_+\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	1.48716e-48
NZ_AP019751.1\|WP_000168845.1\|943011_943773_+\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.29081e-150
NZ_AP019751.1\|WP_000589549.1\|934882_935239_+\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
NZ_AP019751.1\|WP_000422910.1\|933729_934269_+\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	1.62265e-48
NZ_AP019751.1\|WP_000569884.1\|931467_931962_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
NZ_AP019751.1\|WP_000520233.1\|939517_940213_+\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	9.67625e-100

>NZ_AP019751.1|WP_000932228.1|935955_936834_+|DUF1963-domain-containing-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMVLKEMKEETLNQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLDNLPEQQELFPVKEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQAHLKSLDADNEDIPFSGAFSIEFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>NZ_AP019751.1|WP_000290489.1|935396_935777_+|glycine-cleavage-system-protein-GcvH
MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQIEALLTAEKYSEMIGE
>NZ_AP019751.1|WP_000589549.1|934882_935239_+|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>NZ_AP019751.1|WP_001147953.1|934418_934739_-|thioredoxin-family-protein
MQAIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYKDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>NZ_AP019751.1|WP_000422910.1|933729_934269_+|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLSGFLYLTDLEEDMPKAPRKNRNLITLY
>NZ_AP019751.1|WP_000150012.1|932930_933647_+|type-I-3-dehydroquinate-dehydratase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFINDLYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGEPQAPGQIDVTDLKAQVTLY
>NZ_AP019751.1|WP_000974464.1|932360_932783_-|organic-hydroperoxide-resistance-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVSPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>NZ_AP019751.1|WP_000569884.1|931467_931962_-|GNAT-family-N-acetyltransferase
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>NZ_AP019751.1|WP_000255544.1|930695_931313_-|amino-acid-transporter
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIIAAGLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGEAQIMSPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGEMVGSIDKTGKLLTIINKLSSIIIIIVALMILQKLIQLLF
>NZ_AP019751.1|WP_001140696.1|930041_930623_+|histidine-phosphatase-family-protein
MAKTLYLMRHGQTLFNFKGLIQGFGDSPLTELGIAQAQKARSYYETKGINFDLYASSTQERASDTLENVAPNQSYQRFKGLKEWHFGLFEGESVYLFDNLYKPEDLFGDRIVPFKGEARQQVEDRIVKTLHDIMSQTKNNALVVSHGTIMGVFLRYCLKLDEALKHNIGNCNILKFEYDNGTFKFVELIDPNL
>NZ_AP019751.1|WP_001018962.1|937574_937961_+|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>NZ_AP019751.1|WP_001065801.1|937953_938250_+|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>NZ_AP019751.1|WP_000571218.1|938499_939525_+|methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEQGPVTQVFENPQHTVTKRFVKDDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>NZ_AP019751.1|WP_000520233.1|939517_940213_+|ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>NZ_AP019751.1|WP_000732326.1|940230_941052_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>NZ_AP019751.1|WP_000752917.1|941405_941600_+|CsbD-family-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
>NZ_AP019751.1|WP_001183858.1|941832_942684_-|DUF368-domain-containing-protein
MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTSLIIKYFIAGMCASSAMLLPGISGSFMLLVFGVYGTVMLAISEVVKLNFAGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>NZ_AP019751.1|WP_000168845.1|943011_943773_+|Fe-S-cluster-assembly-ATPase-SufC
MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>NZ_AP019751.1|WP_144078939.1|943870_945178_+|Fe-S-cluster-assembly-protein-SufD
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKYFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDENASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSFKSVVIGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
>NZ_AP019751.1|WP_001006454.1|945283_946534_+|cysteine-desulfurase
MNEVAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDVDQLINALKQTKEFFSYEF

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Crispr_ID: NZ_AP019751_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019751_5

1119291-1119383

Orphan

Consensus_repeat	Method
AAAAGCCCCTAACAACTAAAAGTTGTAAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP019751_5

>merge|NZ_AP019751|5|1119291-1119383|CRISPRCasFinder
AAAAGCCCCTAACAACTAAAAGTTGTAAGGAAGAAGAGGGACACATGCGCCGAGCACATGCATAAAATCCCCTAACAACTAAAAGTTGTAAGG

>NZ_AP019751|5|4|1119291-1119383|CRISPRCasFinder
AAAAGCCCCTAACAACTAAAAGTTGTAAGG	AAGAAGAGGGACACATGCGCCGAGCACATGCAT
AAAATCCCCTAACAACTAAAAGTTGTAAGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019751.1\|WP_000273252.1\|1116019_1116826_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NZ_AP019751.1\|WP_000040047.1\|1123589_1125308_+\|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl\|CDD\|224006
NZ_AP019751.1\|WP_000033477.1\|1118233_1118809_-\|ECF-transporter-S-component	unknown	unknown	gnl\|CDD\|227065
NZ_AP019751.1\|WP_000437472.1\|1123320_1123587_+\|phosphocarrier-protein-HPr	unknown	unknown	gnl\|CDD\|237503
NZ_AP019751.1\|WP_000238663.1\|1112426_1112993_+\|phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|223376
NZ_AP019751.1\|WP_001101902.1\|1114507_1115755_+\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|237507
NZ_AP019751.1\|WP_000064214.1\|1119392_1119527_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_000685063.1\|1121398_1122571_+\|class-I-SAM-dependent-rRNA-methyltransferase	unknown	unknown	gnl\|CDD\|224017
NZ_AP019751.1\|WP_000666799.1\|1107086_1107758_+\|phosphoribosylformylglycinamidine-synthase-I	unknown	unknown	gnl\|CDD\|235140
NZ_AP019751.1\|WP_000709290.1\|1113007_1114486_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
NZ_AP019751.1\|WP_000009069.1\|1119678_1120974_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_000638453.1\|1127333_1128353_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|224213
NZ_AP019751.1\|WP_000505966.1\|1122624_1123167_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368297
NZ_AP019751.1\|WP_000032727.1\|1107750_1109940_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	unknown	unknown	gnl\|CDD\|234921
NZ_AP019751.1\|WP_000514290.1\|1128485_1129148_+\|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|223643
NZ_AP019751.1\|WP_000030823.1\|1111395_1112424_+\|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl\|CDD\|235439
NZ_AP019751.1\|WP_000483713.1\|1109918_1111403_+\|amidophosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235984
NZ_AP019751.1\|WP_001289618.1\|1125544_1125778_-\|glutaredoxin-like-protein-NrdH	unknown	unknown	gnl\|CDD\|239274
NZ_AP019751.1\|WP_000381849.1\|1125975_1127337_+\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
NZ_AP019751.1\|WP_000921973.1\|1116818_1118219_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213192

Protein	Function_ID	Function_description	E-value
NZ_AP019751.1\|WP_000273252.1\|1116019_1116826_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	7.19598e-29
NZ_AP019751.1\|WP_000040047.1\|1123589_1125308_+\|phosphoenolpyruvate--protein-phosphotransferase	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
NZ_AP019751.1\|WP_000033477.1\|1118233_1118809_-\|ECF-transporter-S-component	gnl\|CDD\|227065	COG4721, COG4721, ABC-type cobalt transport system, predicted permease component [Inorganic ion transport and metabolism].	4.34592e-70
NZ_AP019751.1\|WP_000437472.1\|1123320_1123587_+\|phosphocarrier-protein-HPr	gnl\|CDD\|237503	PRK13780, PRK13780, phosphocarrier protein HPr; Provisional.	2.44795e-51
NZ_AP019751.1\|WP_000238663.1\|1112426_1112993_+\|phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|223376	COG0299, PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism].	2.03517e-91
NZ_AP019751.1\|WP_001101902.1\|1114507_1115755_+\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|237507	PRK13790, PRK13790, phosphoribosylamine--glycine ligase; Provisional.	0
NZ_AP019751.1\|WP_001289618.1\|1125544_1125778_-\|glutaredoxin-like-protein-NrdH	gnl\|CDD\|239274	cd02976, NrdH, NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase activity that is dependent on TRX reductase, not glutathione (GSH). It is part of the NrdHIEF operon, where NrdEF codes for class Ib ribonucleotide reductase (RNR-Ib), an efficient enzyme at low oxygen levels. Under these conditions when GSH is mostly conjugated to spermidine, NrdH can still function and act as a hydrogen donor for RNR-Ib. It has been suggested that the NrdHEF system may be the oldest RNR reducing system, capable of functioning in a microaerophilic environment, where GSH was not yet available. NrdH from Corynebacterium ammoniagenes can form domain-swapped dimers, although it is unknown if this happens in vivo. Domain-swapped dimerization, which results in the blocking of the TRX reductase binding site, could be a mechanism for regulating the oxidation state of the protein.	1.21197e-16
NZ_AP019751.1\|WP_000685063.1\|1121398_1122571_+\|class-I-SAM-dependent-rRNA-methyltransferase	gnl\|CDD\|224017	COG1092, COG1092, Predicted SAM-dependent methyltransferases [General function prediction only].	2.1836e-146
NZ_AP019751.1\|WP_000666799.1\|1107086_1107758_+\|phosphoribosylformylglycinamidine-synthase-I	gnl\|CDD\|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	1.77638e-140
NZ_AP019751.1\|WP_000709290.1\|1113007_1114486_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NZ_AP019751.1\|WP_000638453.1\|1127333_1128353_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|224213	COG1294, AppB, Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion].	1.67944e-76
NZ_AP019751.1\|WP_000505966.1\|1122624_1123167_+\|hypothetical-protein	gnl\|CDD\|368297	pfam05128, DUF697, Domain of unknown function (DUF697). Family of bacterial hypothetical proteins that is sometimes associated with GTPase domains.	0.00844137
NZ_AP019751.1\|WP_000032727.1\|1107750_1109940_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	gnl\|CDD\|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0
NZ_AP019751.1\|WP_000514290.1\|1128485_1129148_+\|TrkA-family-potassium-uptake-protein	gnl\|CDD\|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	4.35421e-66
NZ_AP019751.1\|WP_000030823.1\|1111395_1112424_+\|phosphoribosylformylglycinamidine-cyclo-ligase	gnl\|CDD\|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
NZ_AP019751.1\|WP_000483713.1\|1109918_1111403_+\|amidophosphoribosyltransferase	gnl\|CDD\|235984	PRK07272, PRK07272, amidophosphoribosyltransferase; Provisional.	0
NZ_AP019751.1\|WP_000381849.1\|1125975_1127337_+\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	2.48829e-165
NZ_AP019751.1\|WP_000921973.1\|1116818_1118219_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	1.87437e-64

>NZ_AP019751.1|WP_000033477.1|1118233_1118809_-|ECF-transporter-S-component
MSKGLKLSEILVTVLISVVFAVIYNLWWFVYNGVQATGLHLEQLTNGVWFMAAIVCYLIIPKPGIALLAEFAAGAGETIIMGRFDIPTIVYAFIQGLACELVFAIFKYQSRSVMVAMLAGFCTAIAAFPIDYFYGYLNEVAGWNLTLFIVFRLISGAVVAGVLSYLLVKALDKTGVTKLFRPAAKEDYDNL
>NZ_AP019751.1|WP_000921973.1|1116818_1118219_-|ABC-transporter-ATP-binding-protein
MLKVSDLRLKYPSGQRKIFDHLNITIQDKEKVLLLGPSGCGKSTLLNVLSGIVPNLIELPMKYDELIVDPLSGVIFQDPDSQFCMPKVYEELAFVLENRQVPREDMDALIINALNMVNLNVTPETYIKDLSGGMKQKLAIVETILQQSKTLFLDEPTAMLDVQATEDLWTKLIELWEDQTVVIVEHKVKHIWNHVDRVILMDYNGNIIADECPEIILQKYVHLLSEYGVWHPRAWEFAPSRVDFPTTNSHLLQFKNGRIIRGKSTLLSFSDLEIGLGEWITITGANGSGKTTLLESIMQLIKYQGDVYFENQRLTKIKHAAKHMYLVYQNPELQFITNSVYDEINIHFNHLSKDQSDDETIQLLKLLDLQNVKDQHPYELSIGQKRRLSVATALSSKADIIFLDEPTFGLDSHNTFQLIKLFQKRINLGQSIVMVTHDDEIIERYPSRRLKISDGALLDCDGDTNV
>NZ_AP019751.1|WP_000273252.1|1116019_1116826_-|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MYEQWKVRQSFVDDVNIITKLFLGIILFFFIIFVHNFDFMLYITILMLVFLLMFNGTQFKITAIFITISIGFALLSSLFMILYGNGSHTILKFGFIHITTESLVRGLHVSLRTIAISFFGILIALTSQVVMIFYSLMQHLKVKSKVAYAFMAAIRMIPLMISSLIQLRRSLKMRYQMIDAANYRGLKRFKHLIIPLLSQNIRKAHQLSVAMESKGFRDGPRTYYYNVPFSYKDIIFIIVLIAIITLAYYCSITLPITGIDDVRLGRVG
>NZ_AP019751.1|WP_001101902.1|1114507_1115755_+|phosphoribosylamine--glycine-ligase
MNVLVIGAGGREHALAYKLNQSNLVKQVFAIPGNEAMTPIAEVHTEISESDHQAILDFAKRQNVDWVVIGPEQPLIDGLADILRANGFKVFGPNKQAAQIEGSKLFAKKIMEKYNIPTADYKEVERKKDALTYIENCELPVVVKKDGLAAGKGVIIADTIEAARSAIEIMYGDEEEGTVVFETFLEGEEFSLMTFVNGDLAVPFDCIAQDHKRAFDHDEGPNTGGMGAYCPVPHISDDVLKLTNETIAQPIAKAMLNEGYQFFGVLYIGAILTKNGPKVIEFNARFGDPEAQVLLSRMESDLMQHIIDLDEGKRTEFKWKNESIVGVMLASKGYPDAYEKGHKVSGFDLNENYFVSGLKKQGDTFVTSGGRVILAIGKGDNVQDAQRDAYEKVSQIQSDHLFYRHDIANKALQLK
>NZ_AP019751.1|WP_000709290.1|1113007_1114486_+|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MKKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYQEVLTRLRNDSLDESYRQSLMIKVFEHTAEYDEAIVRFFKGDKETLRYGENPQQSAYFVRTSNAKHTIAGAKQLHGKQLSYNNIKDADATLALVKKFDTPATVAVKHMNPCGVGIGDTIEQAFQHAYEADSQSIFGGIVALNRAVTPELAEQLHSIFLEVIIAPKFTDEALDILKQKKNVRLLEIDMTIDSNEEEFVSVSGGYLVQDKDNYVVPKEEMKVVTEVAPTDEQWEAMLLGWKVVPSVKSNAIILSNNKQTVGIGAGQMNRVGAAKIALERAIEINDHVALVSDGFFPMGDTVELAAQHGIKAIIQPGGSIKDQDSIDMANKHGIAMVVTGTRHFKH
>NZ_AP019751.1|WP_000238663.1|1112426_1112993_+|phosphoribosylglycinamide-formyltransferase
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEPKQFDSKAAYEQHLVSLLNEDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDCGMDTGEIIEQRQCDIRPDDSKEQLEEKVKKLEYELYPSVIAKIVK
>NZ_AP019751.1|WP_000030823.1|1111395_1112424_+|phosphoribosylformylglycinamidine-cyclo-ligase
MSKAYEQSGVNIHAGYEAVERMSSHVKRTMRKEVIGGLGGFGATFDLSQLNMTAPVLVSGTDGVGTKLKLAIDYGKHDSIGIDAVAMCVNDILTTGAEPLYFLDYIATNKVVPEVIEQIVKGISDACVETNTALIGGETAEMGEMYHEGEYDVAGFAVGAVEKDDYVDSSEVKEGQVVIGLASSGIHSNGYSLVRKLINESGIDLASNFDNRPFIDVFLEPTKLYVKPVLALKKEVSIKAMNHITGGGFYENIPRALPAGYAARIDTTSFPTPKIFDWLQQQGNIDTNEMYNIFNMGIGYTVIVDEKDASRALKILAEQNVEAYQIGHIMKNESTAIELLGV
>NZ_AP019751.1|WP_000483713.1|1109918_1111403_+|amidophosphoribosyltransferase
MFNYSGLNEECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIVVSDQNELKGERGLGLLTEAIKDDQMERLKGYQHAIGHVRYATSGNKGIENIQPFLYHFYDMSVGICHNGNLINAKSLRQNLEKQGAIFHSSSDTEVIMHLIRRSKAPTFEEALKESLRKVKGGFTFAILTKDALYGAVDPNAIRPLVVGKMKDGTYILASETCAIDVLGAEFVQDIHAGEYVVINDKGITVKSYTHHTTTAISAMEYIYFARPDSTIAGKNVHAVRKASGKKLAQESPVNADMVIGVPNSSLSAASGYAEEIGLPYEMGLVKNQYVARTFIQPTQELREQGVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRRIVKMLKDSGANKVHVRIASPEFMFPSFYGIDVSTTAELISASKSPEEIKDYIGADSLAYLSVDGLIESIGLDYDAPYSGLCVESFTGDYPAGLYDYEANYKAHLSHRQKQYISKNKHFFDSEGNLNV
>NZ_AP019751.1|WP_000032727.1|1107750_1109940_+|phosphoribosylformylglycinamidine-synthase-subunit-PurL
MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGDHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGYGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQERMLLVVEKGTEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKDYNTSKNDYTHIDVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAIAQCLTTQD
>NZ_AP019751.1|WP_000666799.1|1107086_1107758_+|phosphoribosylformylglycinamidine-synthase-I
MKFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDYRETSLSGFDGVLIPGGFSFGDYLRSGAMASVAPIISEVKRLAAEGKPVLGVCNGFQILTEIGLLPGALLHNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDEIYQQLKANNQIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERALETLLGTDSGVKLFEAMVKSWREQHV
>NZ_AP019751.1|WP_000064214.1|1119392_1119527_-|hypothetical-protein
MSNENQNKKAAEKAKEVEEKLKDKKEEKTEDINQTKQDIQDTLN
>NZ_AP019751.1|WP_000009069.1|1119678_1120974_+|hypothetical-protein
MSFLRKHAEIIFSYLIGIVSLFTGLIILINLPLIKQLNGGKKVDTHVHNVWEFLNAFFSEIIKVMSRFIGNFPIVSAIVIIIFGILVMLIGHTLLRTIKYDYDISIFFLVIGIMYFIITLILMTQVYGFFAVIFIIPFTIHIGYIVYKDELNQENVKNHFMWIIVSYGISYLITQIALYGRIDANEIESIDILSVNAFFIIMWLLGQMAIWNFLFLRRALPLTKQELGEEEPELSRTSKGNVTNQTKIHLKQLQDKTTEYARKTRRSVDLDKIRAKRDKFKKKVNDIIDIQEDDIPDWMRKPKWVKPMYVELFCGVVIFLFTFLEFNNRNALFVSGDWKLSQTQYVIEWVTLLILLFIIIAYIATTLTFHLKGKFYYLQLFMGSILFFKLLTEFINIMIHGLLLSVFITPTLLLMLLAIIISYSLQLRERP
>NZ_AP019751.1|WP_000685063.1|1121398_1122571_+|class-I-SAM-dependent-rRNA-methyltransferase
MKIATLNKGKETKYFNGYPLIEEEDIYSQDHLKEGDIFQIVTDKSQYVATAYVGRQHKGLGWVLTYDKAQEINTAFFVKLFNTALAERDYYFNIDGTNAFRLFNAEGDGVGGLTIDNYDGHLLIQWYSKGIYKFKYAILEAVRKVFDYKSIYEKVRFKDSEYSGGFVEGDAPEFPIVIEENFTFYNVDLEDGLMTGIFLDQKEVRKKLRDQYAKERHVLNLFSYTGAFSVIAASEASSTTSVDLANRSRSLTEENFGLNAIDPKSQYIYVMDTFDFYKYAARHGHSYDTIVIDPPSFARNKKRTFSVQKDYDKLINGALNILSSEGTLLLCTNASVYPLKQFKNTIKKTLEESGVDYELTEVMGLPKDFKTHPHYKPSKYLKAVFVNIRH
>NZ_AP019751.1|WP_000505966.1|1122624_1123167_+|hypothetical-protein
MGFKNNLTSNLTNKIGNSVFKIENVDGKGAMPTTIQELRERRQRAEAIVKRKSLMSSTMSVVPIPGLDFGVDLKLMKDIIEDVNKIYGLDHKQVNSLGDDVKERIMSAAAIQGSQFIGKRISSAFLKIVIRDVAKRTAAKQTKWFPVVGQAVSASISYYFMNKIGKDHIQKCENVIKNVM
>NZ_AP019751.1|WP_000437472.1|1123320_1123587_+|phosphocarrier-protein-HPr
MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK
>NZ_AP019751.1|WP_000040047.1|1123589_1125308_+|phosphoenolpyruvate--protein-phosphotransferase
MSKLIKGIAASDGVAIAKAYLLVEPDLTFDKNEKVTDVEGEVAKFNSAIEASKVELTKIRNNAEVQLGADKAAIFDAHLLVLDDPELIQPIQDKIKNENANAAKALTDVTTQFVTIFESMDNEYMKERAADIRDVSKRVLSHILGVELPNPSMIDESVVIVGNDLTPSDTAQLNKEFVQGFATNIGGRTSHSAIMSRSLEIPAIVGTKSITQEVKQGDMIIVDGLNGDVIVNPTEDELIAYQDKRERYFADKKELQKLRDADTVTVDGVHAELAANIGTPNDLPGVIENGAQGIGLYRTEFLYMGRDQMPTEEEQFEAYKEVLEAMDGKRVVVRTLDIGGDKELSYLNLPEEMNPFLGYRAIRLCLAQQDIFRPQLRALLRASVYGKLNIMFPMVATINEFREAKAILLEEKENLKNEGHDISDDIELGIMVEIPATAALADVFAKEVDFFSIGTNDLIQYTLAADRMSERVSYLYQPYNPSILRLVKQVIEASHKEGKWTGMCGEMAGDETAIPLLLGLGLDEFSMSATSILKARRQINGLSKNEMTELANRAVDCATQEEVIELVNNYVK
>NZ_AP019751.1|WP_001289618.1|1125544_1125778_-|glutaredoxin-like-protein-NrdH
MSEIIVYTQNDCPPCTFVKNYLNEHQIDFEERNINNQQYRNEMIDFDAFSTPFILLNGNPMYHVDLDEINKVLNIQD
>NZ_AP019751.1|WP_000381849.1|1125975_1127337_+|cytochrome-ubiquinol-oxidase-subunit-I
MDTVEISRFLTAMTLAVHIIFATIGVGMPLMFAIAEFLGIRKNDLQYIAMAKRWAKAYTITVAVGVVTGTIIGLQLSLIWPTFMEMGGHVIALPLFMETFAFFFEAIFLSIYLYTWDRFKNKWTHFLISIPVIIGGSFSAFFITSVNSFMNTPAGFELKNGKMVNVQPIEAMFNPSFIVRSFHVITTAGMTMAFVIASIAAFKLLRNRQPKDTVYHKKALKMSMIVGFFSTLLSMLAGDLSAKFLHKFQPEKLAAYEWHFDTSSHAKLLLFGVLDEKTQQVKGAIELPGLLSFLADNSVKTKVQGLNDFPKSLHPPMIVHYFFDLMVTMGILCFVISGVYVLTLMFKKLRKFSTHKWMLYGILLTGPASMLAIEFGWFLTEMGRQPWIVRGYMRVAEAATQAGGITFVTILFGILYIILMYTCAYVLIRMFKNKPAYEDVNRLAKKQGGEIEK
>NZ_AP019751.1|WP_000638453.1|1127333_1128353_+|cytochrome-d-ubiquinol-oxidase-subunit-II
MIYAFIGITVLWLFLFCYIIIASIDFGAGFFALHSKLTGDEKKINHLISRYLNPVWEVTNVFFVFFFVGFVGFFPESIKYLGTVLLIPGSIALIMISLRNSFYAFENYGQDTKLAWMIMYGVSGLLIPASLSTALTITEGGYINVRNNVIDLDWVQLLLSPFAWSVVFLAIISVLYISSGFLTYYAKKANDEPAYNLTRQWHIFLGPPMIIICLFVFLSLRIQNSEHFYSAVFDYWWMFAISFLFFALASLLTFFKKKHGLAFVFVILQMMFAFFGYGISKLPYLLYPFVKITDAYVNPEMGWTLVIVFILGLLLLLPSLILLLRLFVFDKEYVEGKKS
>NZ_AP019751.1|WP_000514290.1|1128485_1129148_+|TrkA-family-potassium-uptake-protein
MGKEYVVIGLGRFGGSIVRELNALDMDVMAIDHDENRVNEYSDIATHAVVADTTDEAVMKSLGIRNFDHVIVAIGENIQSSTLTTLILKELGVKKVTAKAQNDYHAKILNKIGADTVVHPERDMGRRIAHNVASASVLDYLELADEHSIVELKATEKMAGQSIIDLDIRAQYGINIIAIKRGKEFIISPNPNINLEIGDILIMIGHDNDLNRFEKNIATR

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Crispr_ID: NZ_AP019751_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019751_6

1327587-1327679

Unclear

Consensus_repeat	Method
TAAGAAACACTAATCAATAAATTGATAAG	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NZ_AP019751_6

>merge|NZ_AP019751|6|1327587-1327679|CRISPRCasFinder
TAAGAAACACTAATCAATAAATTGATAAGAAGATTAGAGGAACGCTTGAGCTAAAGCTCATGCATAAGAAACACTAATCAATAAATTGATAAG

>NZ_AP019751|6|5|1327587-1327679|CRISPRCasFinder
TAAGAAACACTAATCAATAAATTGATAAG	AAGATTAGAGGAACGCTTGAGCTAAAGCTCATGCA
TAAGAAACACTAATCAATAAATTGATAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019751.1\|WP_000047343.1\|1325746_1326673_+\|ACP-S-malonyltransferase	unknown	unknown	gnl\|CDD\|223408
NZ_AP019751.1\|WP_000007693.1\|1332562_1333813_+\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
NZ_AP019751.1\|WP_000517908.1\|1319071_1319260_-\|50S-ribosomal-protein-L28	unknown	unknown	gnl\|CDD\|234736
NZ_AP019751.1\|WP_000164332.1\|1317398_1318043_+\|ribulose-phosphate-3-epimerase	unknown	unknown	gnl\|CDD\|223114
NZ_AP019751.1\|WP_000262712.1\|1328996_1332563_+\|chromosome-segregation-protein-SMC	unknown	unknown	gnl\|CDD\|224117
NZ_AP019751.1\|WP_000547905.1\|1318049_1318691_+\|thiamine-diphosphokinase	unknown	unknown	gnl\|CDD\|224480
NZ_AP019751.1\|WP_001261987.1\|1336422_1336926_+\|ribosome-maturation-factor-RimM	unknown	unknown	gnl\|CDD\|234650
NZ_AP019751.1\|WP_144078962.1\|1321927_1323988_+\|ATP-dependent-DNA-helicase-RecG	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|236794
NZ_AP019751.1\|WP_000239748.1\|1324767_1325754_+\|phosphate-acyltransferase-PlsX	unknown	unknown	gnl\|CDD\|235414
NZ_AP019751.1\|WP_000426914.1\|1327769_1328003_+\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|179197
NZ_AP019751.1\|WP_000181404.1\|1337765_1338116_+\|50S-ribosomal-protein-L19	unknown	unknown	gnl\|CDD\|235418
NZ_AP019751.1\|WP_144078963.1\|1326665_1327400_+\|3-oxoacyl-[acyl-carrier-protein]-reductase	unknown	unknown	gnl\|CDD\|235500
NZ_AP019751.1\|WP_001548538.1\|1324190_1324763_+\|transcription-factor-FapR	unknown	unknown	gnl\|CDD\|179847
NZ_AP019751.1\|WP_000863479.1\|1334157_1335525_+\|signal-recognition-particle-protein	unknown	unknown	gnl\|CDD\|236780
NZ_AP019751.1\|WP_000043237.1\|1328118_1328850_+\|ribonuclease-III	unknown	unknown	gnl\|CDD\|234633
NZ_AP019751.1\|WP_000171418.1\|1319702_1320077_+\|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl\|CDD\|224221
NZ_AP019751.1\|WP_000531320.1\|1333799_1334132_+\|putative-DNA-binding-protein	unknown	unknown	gnl\|CDD\|234647
NZ_AP019751.1\|WP_000687328.1\|1336925_1337663_+\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	unknown	unknown	gnl\|CDD\|234581
NZ_AP019751.1\|WP_000268754.1\|1335959_1336235_+\|30S-ribosomal-protein-S16	unknown	unknown	gnl\|CDD\|223306
NZ_AP019751.1\|WP_000623901.1\|1320091_1321738_+\|DAK2-domain-containing-protein	unknown	unknown	gnl\|CDD\|224378

Protein	Function_ID	Function_description	E-value
NZ_AP019751.1\|WP_000047343.1\|1325746_1326673_+\|ACP-S-malonyltransferase	gnl\|CDD\|223408	COG0331, FabD, (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism].	2.53926e-134
NZ_AP019751.1\|WP_000007693.1\|1332562_1333813_+\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	0
NZ_AP019751.1\|WP_000517908.1\|1319071_1319260_-\|50S-ribosomal-protein-L28	gnl\|CDD\|234736	PRK00359, rpmB, 50S ribosomal protein L28; Reviewed.	1.3072e-18
NZ_AP019751.1\|WP_000164332.1\|1317398_1318043_+\|ribulose-phosphate-3-epimerase	gnl\|CDD\|223114	COG0036, Rpe, Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism].	1.52718e-114
NZ_AP019751.1\|WP_000262712.1\|1328996_1332563_+\|chromosome-segregation-protein-SMC	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	0
NZ_AP019751.1\|WP_000547905.1\|1318049_1318691_+\|thiamine-diphosphokinase	gnl\|CDD\|224480	COG1564, THI80, Thiamine pyrophosphokinase [Coenzyme metabolism].	1.16343e-81
NZ_AP019751.1\|WP_001261987.1\|1336422_1336926_+\|ribosome-maturation-factor-RimM	gnl\|CDD\|234650	PRK00122, rimM, 16S rRNA-processing protein RimM; Provisional.	1.02289e-68
NZ_AP019751.1\|WP_144078962.1\|1321927_1323988_+\|ATP-dependent-DNA-helicase-RecG	gnl\|CDD\|236794	PRK10917, PRK10917, ATP-dependent DNA helicase RecG; Provisional.	0
NZ_AP019751.1\|WP_000239748.1\|1324767_1325754_+\|phosphate-acyltransferase-PlsX	gnl\|CDD\|235414	PRK05331, PRK05331, phosphate acyltransferase PlsX.	6.1953e-178
NZ_AP019751.1\|WP_000426914.1\|1327769_1328003_+\|acyl-carrier-protein	gnl\|CDD\|179197	PRK00982, acpP, acyl carrier protein; Provisional.	5.23888e-31
NZ_AP019751.1\|WP_000181404.1\|1337765_1338116_+\|50S-ribosomal-protein-L19	gnl\|CDD\|235418	PRK05338, rplS, 50S ribosomal protein L19; Provisional.	6.77895e-70
NZ_AP019751.1\|WP_144078963.1\|1326665_1327400_+\|3-oxoacyl-[acyl-carrier-protein]-reductase	gnl\|CDD\|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	1.59216e-140
NZ_AP019751.1\|WP_001548538.1\|1324190_1324763_+\|transcription-factor-FapR	gnl\|CDD\|179847	PRK04424, PRK04424, transcription factor FapR.	2.37773e-98
NZ_AP019751.1\|WP_000863479.1\|1334157_1335525_+\|signal-recognition-particle-protein	gnl\|CDD\|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0
NZ_AP019751.1\|WP_000043237.1\|1328118_1328850_+\|ribonuclease-III	gnl\|CDD\|234633	PRK00102, rnc, ribonuclease III; Reviewed.	4.78039e-115
NZ_AP019751.1\|WP_000171418.1\|1319702_1320077_+\|Asp23/Gls24-family-envelope-stress-response-protein	gnl\|CDD\|224221	COG1302, COG1302, Uncharacterized protein conserved in bacteria [Function unknown].	4.1554e-37
NZ_AP019751.1\|WP_000531320.1\|1333799_1334132_+\|putative-DNA-binding-protein	gnl\|CDD\|234647	PRK00118, PRK00118, putative DNA-binding protein; Validated.	5.84113e-47
NZ_AP019751.1\|WP_000687328.1\|1336925_1337663_+\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	gnl\|CDD\|234581	PRK00026, trmD, tRNA (guanine-N(1)-)-methyltransferase; Reviewed.	2.98496e-164
NZ_AP019751.1\|WP_000268754.1\|1335959_1336235_+\|30S-ribosomal-protein-S16	gnl\|CDD\|223306	COG0228, RpsP, Ribosomal protein S16 [Translation, ribosomal structure and biogenesis].	3.01687e-41
NZ_AP019751.1\|WP_000623901.1\|1320091_1321738_+\|DAK2-domain-containing-protein	gnl\|CDD\|224378	COG1461, COG1461, Predicted kinase related to dihydroxyacetone kinase [General function prediction only].	0

>NZ_AP019751.1|WP_144078963.1|1326665_1327400_+|3-oxoacyl-[acyl-carrier-protein]-reductase
MTKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVAPGFIVSDMTDALSDEVKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQTIHVNGGMYM
>NZ_AP019751.1|WP_000047343.1|1325746_1326673_+|ACP-S-malonyltransferase
MSKTAIIFPGQGAQKVGMAQDLFNNNDQATEILTSAAKTLDFDILETMFTDEEGKLGETENTQPALLTHSSALLAALKNLNPDFTMGHSLGEYSSLVAADVLSFEDAVKIVRKRGQLMAQAFPTGVGSMAAVLGLDFDKVDEICKSLSSDDKIIEPANINCPGQIVVSGHKALIDELVEKGKSLGAKRVMPLAVSGPFHSSLMKVIEEDFSSYINQFEWRDAKFPVVQNVNAQGETDKEVIKSNMVKQLYSPVQFINSTEWLIDQGVDHFIEIGPGKVLSGLIKKINRDVKLTSIQTLEDVKGWNEND
>NZ_AP019751.1|WP_000239748.1|1324767_1325754_+|phosphate-acyltransferase-PlsX
MVKLAIDMMGGDNAPDIVLEAVQKAVEDFKDLEIILFGDEKKYNLNHERIEFRHCSEKIEMEDEPVRAIKRKKDSSMVKMAEAVKSGEADGCVSAGNTGALMSAGLFIVGRIKGVARPALVVTLPTIDGKGFVFLDVGANADAKPEHLLQYAQLGDIYAQKIRGIDNPKISLLNIGTEPAKGNSLTKKSYELLNQDHSLNFVGNIEAKTLMDGDTDVVVTDGYTGNMVLKNLEGTAKSIGKMLKDTIMSSTKNKLAGAILKKDLAEFAKKMDYSEYGGSVLLGLEGTVVKAHGSSNAKAFYSAIRQAKIAGEQNIVQTMKETVGESNE
>NZ_AP019751.1|WP_001548538.1|1324190_1324763_+|transcription-factor-FapR
MRGETLKLKKDKRREAIRQQIDSNPFITDHELSDLFQVSIQTIRLDRTYLNIPELRKRIKLVAEKNYDQISSIEEQEFIGDLIQVNPNVKAQSILDITSDSVFHKTGIARGHVLFAQANSLCVALIKQPTVLTHESSIQFIEKVKLNDTVRAEARVVNQTAKHYYVEVKSYVKHTLVFKGNFKMFYDKRG
>NZ_AP019751.1|WP_144078962.1|1321927_1323988_+|ATP-dependent-DNA-helicase-RecG
MAKVNLIESPYSLLQLKGIGPKKIEVLQQLNIHTVEDLVLYLPTRYEDNTVIDLNQAEDQSNVTIEGQVYTAPVVAFFGRNNSKLTVHLMVNNIAVKCIFFNQPYLKKKIELNQTITVKGKWNRVKQEITGNRVFFNSQGTQTQENADVQLEPVYRIKEGIKQKQIRDQIRQALNDVTIHEWLTDELREKYKLETLDFTLNTLHHPKSKEDLLRARRTYAFTELFLFELRIQWLNRLEKSSDEAIEIDYGLDQVKSFIDRLPFELTEAQKSSVNEIFRDLKAPIRMHRLLQGDVGSGKTVVAAICMYALKTAGYQSALMVPTEILAEQHAESLMALFGDSMNVALLTGSVKGKKRKILLEQLENGTIDCLIGTHALIQDDVIFHNVGLVITDEQHRFGVNQRQLLREKGAMTNVLFMTATPIPRTLAISVFGEMDVSSIKQLPKGRKPIITTWAKHEQYDKVLMQMTSELKKGRQAYVICPLIESSEHLEDVQNVVALYESLQQYYGVSRVGLLHGKLSADEKDEVMQKFSNHEIDVLVSTTVVEVGVNVPNATFMMIYDADRFGLSTLHQLRGRVGRSDQQSYCVLIASPKTETGIERMTIMTQTTDGFELSERDLEMRGPGDFFGVKQSGLPDFLVANLVEDYRMLEVARDEAAELIQSGVFFENTYQHLRHFVEENLLHRSFD
>NZ_AP019751.1|WP_000623901.1|1320091_1321738_+|DAK2-domain-containing-protein
MISKINGKLFADMIIQGAQNLSNNADLVDSLNVYPVPDGDTGTNMNLTMTSGREEVENNLSKNIGELGKTFSKGLLMGARGNSGVILSQLFRGFCKNIESESEINSKLLAESFQAGVETAYKAVMKPVEGTILTVAKDAAQAAIEKANNTEDCIELMEYIIVKANESLENTPNLLAVLKEVGVVDSGGKGLLCVYEGFLKALKGEKVEAKVAKIDKDEFVHDEHDFHGVINTEDIIYGYCTEMMVRFGKNKKAFDEQEFRQDMSQFGDSLLVINDEEIVKVHVHTEYPGKVFNYGQQYGELIKLKVENMREQHREVIRKEQHTAKPKMETVETAIITISMGEGISEIFKSMGATHIISGGQTMNPSTEDIVKVIEQSKCKRAIILPNNKNILMASEQAASIVDAEAVVIPTKSIPQGISALFQCDVDATLEENKAQMADSVNNVKSGSLTYAVRDTKIDGVEIKKDAFMGLIEDKIVSSQSDQLTTVTELLNEMLAEDSEILTVIIGQDAEQAVTDNMINWIEEQYPDVEVEVHEGGQPIYQYFFSVE
>NZ_AP019751.1|WP_000171418.1|1319702_1320077_+|Asp23/Gls24-family-envelope-stress-response-protein
MTLEISNDYGKIDISNEVIASVVGGKAVECYGIVGMASRQQVRDGIAEILGHENYAKGIKVTENNGVVDIDMYIIVSYGVKISEVANNVQSTVKYTLEKSLNVSVNSINIYVQGVRVNNTGKKA
>NZ_AP019751.1|WP_000517908.1|1319071_1319260_-|50S-ribosomal-protein-L28
MGKQCFVTGRKASTGNRRSHALNSTKRRWNANLQKVRILVDGKPKKVWVSARALKSGKVTRV
>NZ_AP019751.1|WP_000547905.1|1318049_1318691_+|thiamine-diphosphokinase
MHINLLCSDRHLPQDIWAKSNEGKWGGVDRGALILLKHQIIPFFSVGDFDSVSKEERQLLTEQLQIKPVQAEKADTDLALAVDKAVALGFDSITIYGATGGRLDHFFGAIQLLLKKAYYKHDVHIEVIDQQNKIELLPKGQHTVEKDKSYPYISFIPMTDDVELSLAGFKYNLARQMLNIGSTLTISNEIESLQAKVTVHDGLILQIRSTDLN
>NZ_AP019751.1|WP_000164332.1|1317398_1318043_+|ribulose-phosphate-3-epimerase
MTKLYPSLLSVDFLDLQHELKRLEEAGVDGVHFDVMDGQFVPNISIGLPILDAVRKGTTLPIDVHLMIENPEKYIASFAEHGADMISIHVESTPHIHRAIQMIKHLDKKAGVVINPGTPISQIEPILDIVDYVLVMTVNPGFGGQSFIDQCVEKIAGLNAIKMERQLNFDIEVDGGVNTDTAKVCVENGATMLVTGSFFFKQEDYKKVTQALKG
>NZ_AP019751.1|WP_000426914.1|1327769_1328003_+|acyl-carrier-protein
MENFDKVKDIIVDRLGVDADKVTEDASFKDDLGADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKFINSLEK
>NZ_AP019751.1|WP_000043237.1|1328118_1328850_+|ribonuclease-III
MSKQKKSEIVNRFRKRFDTKMTELGFTYQNIDLYQQAFSHSSFINDFNMNRLDHNERLEFLGDAVLELTVSRYLFDKHPNLPEGNLTKMRATIVCEPSLVIFANKIGLNEMILLGKGEEKTGGRTRPSLISDAFEAFIGALYLDQGLDIVWKFAEKVIFPHVEQNELLGVVDFKTQFQEYVHQQNKGDVTYNLIKEEGPAHHRLFTSEVILQGEAIAEGKGKTKKESEQRAAESAYKQLKQIK
>NZ_AP019751.1|WP_000262712.1|1328996_1332563_+|chromosome-segregation-protein-SMC
MVYLKSIDAIGFKSFADQTNVQFDKGVTAIVGPNGSGKSNITDAIKWVLGEQSAKSLRGSKMEDIIFSGAEHRKAQNYAEVQLRLDNHSKKLSVDENEVIVTRRLYRSGESEYYINNDRARLKDIADLFLDSGLGKEAYSIISQGRVDEILNAKPIDRRQIIEESAGVLKYKKRKAESLNKLDQTEDNLTRVEDILYDLEGRVEPLKEEAAIAKEYKTLSHQMKHSDIVVTVHDIDQYTNDNRQLDQRLNDLQGQQANKEADKQRLSQQIQQYKGKRHQLDNDVESLNYQLVKATEAFEKYTGQLNVLEERKKNQSETNARYEEEQENLMELLENISNEISGAQDTYKSLKSKQKELNAVIRELEEQLYVSDEAHDEKLEEIKNEYYTLMSEQSDVNNDIRFLKHTIEENEAKKSRLDSRLVEVFEQLKDIQGQIKTTKKEYQQTNKELSAVDKEIKNIEKDLTDTKKAQNEYEEKLYQAYRYTEKMKTRIDSLATQEEEYTYFFNGVKHILKAKNKELKGIHGAVAEIIDVPSKLTQAIETALGASLQHVIVDSEKDGRQAIQFLKERNLGRATFLPLNVIQSRVVATDIKSIAKEANGFISIASEAVKVAPEYQNIIGNLLGNTIIVDHLKHANELARAIKYRTRIVTLEGDIVNPGGSMTGGGARKSKSILSQKDELTTMRHQLEDYLRQTESFEQQFKELKIKSDQLSELYFEKSQKHNTLKEQVHHFEMELDRLTTQETQIKNDHEEFEFEKNDGYTSDKSRQTLSEKETHLESIKASLKRLEDEIERYTKLSKEGKESVTKTQQTLHQKQSDLAVVKERIKTQQQTIDRLNNQNQQTKHQLKDVKEKIALFNSDEVMGEQAFQNIKDQINGQQETRTRLSDELDKLKQQRIELNEQIDAQEAKLQVCHQDILAIENHYQDIKAEQSKLDVLIHHAIDHLNDEYQLTVERAKSEYTSDESIDALRKKVKLMKMSIDELGPVNLNAIEQFEELNERYTFLSEQRTDLRKAKETLEQIISEMDQEVTERFKETFHAIQGHFTAVFKQLFGGGDAELQLTEADYLTAGIDIVVQPPGKKLQHLSLLSGGERALTAIALLFAILKVRSAPFVILDEVEAALDEANVIRYAKYLNELSDETQFIVITHRKGTMEFADRLYGVTMQESGVTKLVSVNLNTIDDVLKEEQ
>NZ_AP019751.1|WP_000007693.1|1332562_1333813_+|signal-recognition-particle-docking-protein-FtsY
MSFFKRLKDKFATNKENEEVKSLTEEQGQDKLEDTHSESSTQDANDLAENAEVKKKPRKLSEADFDDDGLISIEDFEEIEAQKMGAKFKAGLEKSRQNFQEQLNNLIARYRKVDEDFFEALEEMLITADVGFNTVMTLTEELRMEAQRRNIQDTEDLREVIVEKIVEIYHQEDDNSEAMNLEDGRLNVILMVGVNGVGKTTTIGKLAYRYKMEGKKVMLAAGDTFRAGAIDQLKVWGERVGVDVISQSEGSDPAAVMYDAINAAKNKGVDILICDTAGRLQNKTNLMQELEKVKRVINRAVPDAPHEALLCLDATTGQNALSQARNFKEVTNVTGIVLTKLDGTAKGGIVLAIRNELHIPVKYVGLGEQLDDLQPFNPESYVYGLFADMIEQNEEITTVENDQIVTEEKDDNHGSK
>NZ_AP019751.1|WP_000531320.1|1333799_1334132_+|putative-DNA-binding-protein
MGQNDLVKTLRMNYLFDFYQSLLTNKQRNYLELFYLEDYSLSEIADTFNVSRQAVYDNIRRTGDLVEDYEKKLELYQKFEQRREIYDEMKQHLSNPEQIQRYIQQLEDLE
>NZ_AP019751.1|WP_000863479.1|1334157_1335525_+|signal-recognition-particle-protein
MAFEGLSERLQATMQKMRGKGKLTEADIKIMMREVRLALLEADVNFKVVKEFIKTVSERALGSDVMQSLTPGQQVIKIVQDELTQLMGGENTSINMSNKPPTVVMMVGLQGAGKTTTAGKLALLMRKKYNKKPMLVAADIYRPAAINQLQTVGKQIDIPVYSEGDQVKPQQIVTNALKHAKEEHLDFVIIDTAGRLHIDEALMNELKEVKDIAKPNEIMLVVDSMTGQDAVNVAESFDDQLDVTGVTLTKLDGDTRGGAALSIRSVTQKPIKFVGMSEKLDGLELFHPERMASRILGMGDVLSLIEKAQQDVDQEKAKDLEKKMRESSFTLDDFLEQLDQVKNLGPLDDIMKMIPGMNKMKGLDKLNMSEKQIDHIKAIIQSMTPAERNNPDTLNVSRKKRIAKGSGRSLQEVNRLMKQFNDMKKMMKQFTGGGKGKKGKRNQMQNMLKGMNLPF
>NZ_AP019751.1|WP_000268754.1|1335959_1336235_+|30S-ribosomal-protein-S16
MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQIGTYNPTSANAPEIKVDEALALKWLNDGAKPTDTVHNILSKEGIMKKFDEQKKAK
>NZ_AP019751.1|WP_001261987.1|1336422_1336926_+|ribosome-maturation-factor-RimM
MRVEVGQIVNTHGIKGEIKVKSNSDFTDVRFQPGQVLTVVHNNNDLEYTVKSHRVHKGLHMLTFEGINNINDIEHLKGSSIYQERDHEDIVLEENEFYYSDIIGCTVFDDQETPIGRVINIFETGANDVWVIKGSKEYLIPYIADVVKEVDVENKKIIITPMEGLLD
>NZ_AP019751.1|WP_000687328.1|1336925_1337663_+|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD
MKIDYLTLFPEMFDGVLNHSIMKRAQENNKLQINTVNFRDYAINKHNQVDDYPYGGGQGMVLKPEPVFNAMEDLDVTEQTRVILMCPQGEPFSHQKAVELSKADHIVFICGHYEGYDERIRTHLVTDEISMGDYVLTGGELPAMTMTDAIVRLIPGVLGNEQSHQDDSFSDGLLEFPQYTRPREFKGLTVPDVLLSGNHANIDAWRHEQKLIRTYNKRPDLIEKYPLTNADKQILERYKIGLKKG
>NZ_AP019751.1|WP_000181404.1|1337765_1338116_+|50S-ribosomal-protein-L19
MTNHKLIEAVTKSQLRTDLPSFRPGDTLRVHVRIIEGTRERIQVFEGVVIKRRGGGVSETFTVRKISSGVGVERTFPLHTPKIEKIEVKRRGKVRRAKLYYLRSLRGKAARIQEIR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_AP019751_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019751_7

1766585-1766670

Orphan

Consensus_repeat	Method
TCTGTGTTGGGGCCCCATCCCCAACTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP019751_7

>merge|NZ_AP019751|7|1766585-1766670|CRISPRCasFinder
TCTGTGTTGGGGCCCCATCCCCAACTTGCACATTATTGAAATCTGACTTTTGGTCAGCTTCTGTGTTGGGGCCCCGTCCCCAACTT

>NZ_AP019751|7|6|1766585-1766670|CRISPRCasFinder
TCTGTGTTGGGGCCCCATCCCCAACTT	GCACATTATTGAAATCTGACTTTTGGTCAGCT
TCTGTGTTGGGGCCCCGTCCCCAACTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019751.1\|WP_000409158.1\|1767971_1769114_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
NZ_AP019751.1\|WP_000066094.1\|1766852_1767971_-\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664
NZ_AP019751.1\|WP_000009238.1\|1770675_1770822_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_000137775.1\|1757224_1758148_-\|U32-family-peptidase	unknown	unknown	gnl\|CDD\|223896
NZ_AP019751.1\|WP_000567030.1\|1765603_1766272_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NZ_AP019751.1\|WP_114288281.1\|1760151_1762782_-\|alanine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234701
NZ_AP019751.1\|WP_000044799.1\|1774319_1776086_-\|aspartate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234775
NZ_AP019751.1\|WP_000682646.1\|1773085_1773859_-\|tRNA-threonylcarbamoyladenosine-dehydratase	unknown	unknown	gnl\|CDD\|224100
NZ_AP019751.1\|WP_000426912.1\|1759828_1760089_-\|IreB-family-regulatory-phosphoprotein	unknown	unknown	gnl\|CDD\|180108
NZ_AP019751.1\|WP_001283312.1\|1763124_1765602_-\|ATP-dependent-RecD-like-DNA-helicase	unknown	unknown	gnl\|CDD\|273632
NZ_AP019751.1\|WP_000134779.1\|1759073_1759382_-\|DUF1292-domain-containing-protein	unknown	unknown	gnl\|CDD\|184235
NZ_AP019751.1\|WP_000985895.1\|1769425_1770439_+\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274646
NZ_AP019751.1\|WP_001790559.1\|1773858_1773987_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_000342266.1\|1758150_1758789_-\|O-methyltransferase	unknown	unknown	gnl\|CDD\|226607
NZ_AP019751.1\|WP_000939059.1\|1759396_1759825_-\|Holliday-junction-resolvase-RuvX	unknown	unknown	gnl\|CDD\|223886
NZ_AP019751.1\|WP_000102740.1\|1771650_1772925_+\|replication-associated-recombination-protein-A	unknown	unknown	gnl\|CDD\|237355
NZ_AP019751.1\|WP_144078974.1\|1755944_1757213_-\|U32-family-peptidase-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|223896
NZ_AP019751.1\|WP_000752909.1\|1770861_1771044_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_AP019751.1\|WP_000704122.1\|1771143_1771566_-\|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224870
NZ_AP019751.1\|WP_000648617.1\|1755321_1755945_-\|uridine-kinase	unknown	unknown	gnl\|CDD\|235492

Protein	Function_ID	Function_description	E-value
NZ_AP019751.1\|WP_000409158.1\|1767971_1769114_-\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	0
NZ_AP019751.1\|WP_000066094.1\|1766852_1767971_-\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
NZ_AP019751.1\|WP_000682646.1\|1773085_1773859_-\|tRNA-threonylcarbamoyladenosine-dehydratase	gnl\|CDD\|224100	COG1179, COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism].	1.59061e-126
NZ_AP019751.1\|WP_000137775.1\|1757224_1758148_-\|U32-family-peptidase	gnl\|CDD\|223896	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones].	4.87045e-104
NZ_AP019751.1\|WP_000567030.1\|1765603_1766272_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	5.22121e-16
NZ_AP019751.1\|WP_114288281.1\|1760151_1762782_-\|alanine--tRNA-ligase	gnl\|CDD\|234701	PRK00252, alaS, alanyl-tRNA synthetase; Reviewed.	0
NZ_AP019751.1\|WP_000044799.1\|1774319_1776086_-\|aspartate--tRNA-ligase	gnl\|CDD\|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0
NZ_AP019751.1\|WP_000426912.1\|1759828_1760089_-\|IreB-family-regulatory-phosphoprotein	gnl\|CDD\|180108	PRK05473, IreB-like, IreB family regulatory phosphoprotein. IreB (EF1202) was characterized in Enterococcus faecalis as a small protein, well-conserved in the Firmicutes. It belongs to a system that includes the Ser/Thr protein kinase IreK, and phosphatase IreP, undergoes phosphorylation on threonine residues, and is involved in regulating cephalosporin resistance. This family was previously named DUF965 by Pfam model pfam06135.	3.05024e-47
NZ_AP019751.1\|WP_001283312.1\|1763124_1765602_-\|ATP-dependent-RecD-like-DNA-helicase	gnl\|CDD\|273632	TIGR01448, recD_rel, helicase, putative, RecD/TraA family. This model describes a family similar to RecD, the exodeoxyribonuclease V alpha chain of TIGR01447. Members of this family, however, are not found in a context of RecB and RecC and are longer by about 200 amino acids at the amino end. Chlamydia muridarum has both a member of this family and a RecD. [Unknown function, Enzymes of unknown specificity].	0
NZ_AP019751.1\|WP_000134779.1\|1759073_1759382_-\|DUF1292-domain-containing-protein	gnl\|CDD\|184235	PRK13678, PRK13678, hypothetical protein; Provisional.	1.28539e-26
NZ_AP019751.1\|WP_000985895.1\|1769425_1770439_+\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|274646	TIGR03558, oxido_grp_1, luciferase family oxidoreductase, group 1. The Pfam domain family pfam00296 is named for luciferase-like monooxygenases, but the family also contains several coenzyme F420-dependent enzymes. This protein family represents a well-resolved clade within family pfam00296 and shows no restriction to coenzyme F420-positive species, unlike some other clades within pfam00296. [Unknown function, Enzymes of unknown specificity].	1.49102e-173
NZ_AP019751.1\|WP_000342266.1\|1758150_1758789_-\|O-methyltransferase	gnl\|CDD\|226607	COG4122, COG4122, Predicted O-methyltransferase [General function prediction only].	1.23148e-73
NZ_AP019751.1\|WP_000939059.1\|1759396_1759825_-\|Holliday-junction-resolvase-RuvX	gnl\|CDD\|223886	COG0816, COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) [DNA replication, recombination, and repair].	3.40149e-56
NZ_AP019751.1\|WP_000102740.1\|1771650_1772925_+\|replication-associated-recombination-protein-A	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NZ_AP019751.1\|WP_144078974.1\|1755944_1757213_-\|U32-family-peptidase-C-terminal-domain-containing-protein	gnl\|CDD\|223896	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones].	3.76391e-149
NZ_AP019751.1\|WP_000752909.1\|1770861_1771044_-\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	4.22501e-07
NZ_AP019751.1\|WP_000704122.1\|1771143_1771566_-\|Rrf2-family-transcriptional-regulator	gnl\|CDD\|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	5.58388e-46
NZ_AP019751.1\|WP_000648617.1\|1755321_1755945_-\|uridine-kinase	gnl\|CDD\|235492	PRK05480, PRK05480, uridine/cytidine kinase; Provisional.	5.13835e-138

>NZ_AP019751.1|WP_000567030.1|1765603_1766272_-|tetratricopeptide-repeat-protein
MIDQQTIYQYIQNGKIEEALQALFGNIEENPTIIENYINAGIVLADANEIEKAERFFQKALTIDPKNGVVFYNLANVYYNQQRYQEAIKLYQQALQTEIEQVDCNYMIGMAFNQLESFKLALPYLMTAAELDKDKDAEVQFQYGLVLCQLEMFNEAITQLKHVLTIDKNHVDARYNLGLALFMKNEDIDEAITHFKEAVTIDPKHLLSQHALKTFTKMKEEE
>NZ_AP019751.1|WP_001283312.1|1763124_1765602_-|ATP-dependent-RecD-like-DNA-helicase
MSDPTLFDYSMIKGTVEAILFQNSDNFYTVLKVDTIETNEDFDTMPTVVGFLPNIVEGDVYTFKGQVVDHPRYGKQLKAETFEKEMPQTKEAIISYLSSDLFKGVGKKTAQNIVNTLGDNAINDILDDHSVLEKVSGLSKKKQKQIAEQISANQESEKIMIRLHDLGFGPKLSMAIYQFYLGDTLTILDRNPYQLIYDIKGIGFNKADQLARNIGIAYNDNERLKAALLYTLEEECIKQGHTYLPINVVIDLTVDVLNYQDEEVIEPEKLDEMLQYLNEEKRLIIDNEQVAIPSLYYSEIKSVQNLFRIKTHTNKLTEIEQSDLQMHIGEIEDANQVNYAASQKEALQTAINSKVMLLTGGPGTGKTTVIKGIVELYAEIHGLSLDYDDYVNDDYPVVLAAPTGRASKRLQESTGLEAMTIHRLIGWNQDTKPEDILENEINARLIIIDEMSMVDTWLFHQFLSAVPLDAQLIFVGDEDQLPSVGPGQVFKDLIESKAIPRVNLTEVYRQQDGSSIIELAHRMKLGQKIDITQRFHDRSFINCQANQIPTVVEKVVTSAVNKGYTMADIQVLAPMYKGNAGIKRLNQVLQDILNPKKKDTREIEFGDVVFRKGDKVLQLVNRPNDNIFNGDIGVIVGIFWAKENALNKDVLVVDFEGNEITFTKQDMMELTHAYCTSIHKSQGSEFPIVIMPIVKQYFRMLQRPILYTGLTRAKTSLVLLGDPEAFDIGLKTNGQARLTQLCTLLKNYFNSEDEEMLENTATNDTGASQTTIDDQVEAPMSSNDSGEVTSDSTKTDINVLTEATMFKIDPMINMGEITPYDFIER
>NZ_AP019751.1|WP_114288281.1|1760151_1762782_-|alanine--tRNA-ligase
MKKLKASEIRQKYLDFFVEKGHMVEPSAPLVPIDDDTLLWINSGVATLKKYFDGRETPKKPRIVNSQKAIRTNDIENVGFTARHHTFFEMLGNFSIGDYFKQEAIEFAWEFLTSDKWMGMEPDKLYVTIHPEDMEAYNIWHKDIGLEESRIIRIEGNFWDIGEGPSGPNTEIFYDRGEAYGQDDPAEEMYPGGENERYLEVWNLVFSEFNHNKDHSYTPLPNKNIDTGMGLERMASVSQNVRTNYETDLFMPIMNEIEKVSGKQYLVNNEQDVAFKVIADHIRTIAFAISDGALPANEGRGYVLRRLLRRAVRFSQTLGINEPFMYKLVDIVADIMEPYYPNVKEKADFIKRVIKSEEERFHETLEDGLAILNELIKKAKATTNEINGKDAFKLYDTYGFPIELTEEIAVQAGLKVDMTTFESEMQQQRDRARQARQNSQSMQVQSEVLKNITSASTFVGYDTATAQTTLTHLIYNGEEVSQVEAGETVYFMLTETPFYAVSGGQVTDTGIVYNDNFEIAVSEVTKAPNGQNLHKGVVQFGQVNVGATVSAEVNQNDRRDIQKNHSATHLLHAALKSVLGDHVNQAGSLVEADRLRFDFSHFGPMTNDEIDQVERLVNEEIWKGIDVNIQEMDIASAKEMGAMALFGEKYGDVVRVVNMAPFSIELCGGIHVRNTSEIGLFKIVSESGTGAGVRRIEALTGKAAFLYLEDIQEKFNTMKSQLKVKSDDQVVDKLTQLQDEEKALLKQLEQRDKEITSLKMGNIENQVEEINGYKVLVTEVDVPNAKAIRSTMDDFKSKLQDTIIILASNVDDKVSMVATVPKSLTNNVKAGDLIKQMAPIVGGKGGGRPDMAQGGGTQPENISKSLSFIKDYIKNL
>NZ_AP019751.1|WP_000426912.1|1759828_1760089_-|IreB-family-regulatory-phosphoprotein
MENFDKTMKFDYEELPTQDVRDVLNNVYRTLDERGYNAVNQIVGYLLSGDPAYIPRQNEARNQIRHIDRDVIMEELVSYYLKEQNK
>NZ_AP019751.1|WP_000939059.1|1759396_1759825_-|Holliday-junction-resolvase-RuvX
MLQHKILGLDVGSRTVGIAISDIMGWTAQGLDTLRINEENNELGIDQLVDIIKKHNVGTVVIGLPKNMNNSIGFRGEASLTYKEKLLEAYPSIEIVMWDERLSTMAAERSLLEADVSRQKRKQVIDKMAAVFILQGYLDSLH
>NZ_AP019751.1|WP_000134779.1|1759073_1759382_-|DUF1292-domain-containing-protein
MTEHNHDSQLEINNEEELLTLFDEEGNEVLYRKVLEFYHPEFKKEYVILAEEGAQSDEDDMIELVPMINEPDESGDGGKLVPIETDEEWDMIEEVVNTEMEE
>NZ_AP019751.1|WP_000342266.1|1758150_1758789_-|O-methyltransferase
MDDLNKKYLIDLHQHQNSSIEVLREFAEVNEVPIVDRLTLDLIKQLIRMNNVKNILEIGTAIGYSSMQFASISDDIHVTTIERNETMIQYAKQNLATYHFENQVRIIEGNALEQFENVNDKVYDMIFIDAAKAQSKKFFEIYTPLLKHQGLVITDNVLYHGFVSDIGIVRSRNVRQMVKKVQDYNEWLIKQPGYTTNFLNIDDGLAISIKGE
>NZ_AP019751.1|WP_000137775.1|1757224_1758148_-|U32-family-peptidase
MTELLVTPKSLSHMETLIDLGADAFVIGEQKFGLRLPGEFNRQQMTEAVALAHKNDKKVYAAVNGLFHNYHLDAVEDYINFLHEIRVDRIIFGDPAVVMYVKAQENPIPLHWNAETLVTNHFQCNYWGKRGASRAVLARELNLDEIINIKENSNVEIEVQVQGMTCMFQSKRMLLGNYYTFQDRQMKIERRNDEQSLLLYDEERQNNYPVYEDYNGTHIMSPNDICLIEELAPFFEAGIDSFKIDGILQTEEYINVVTEQYRQAIDLYNEDPEIYEDEKFMLMDPIEEIQPDHRPFDEGFLYKQTVY
>NZ_AP019751.1|WP_144078974.1|1755944_1757213_-|U32-family-peptidase-C-terminal-domain-containing-protein
MKTIEKIKSTPKTVMKKPELLAPAGNLEKLKIAVHYGADAVFLGGQEYGLRSNADNFTMEEIAEGVEFANRYGAKIYVTTNIIAHDENIEGLESYLRNLEKTGATGIIVADPLIIETCKEVAPKLEIHLSTQQSLSNYKAVEYWKEEGLDRVVLARETGAMEMREMKEKVDIEIEAFIHGAMCIAYSGRCTLSNHMTARDSNRGGCCQSCRWDYELLEVDDNGELDVFYNQGEVTPFAMSPKDLKLIESIPQMMDIGVDSLKIEGRMKSIHYIATVVSVYRKVIDAYAADPDNFKINPEWLIELDKCANRDTAPAFFEGTPGYEEQMFGQQQSKKSPFDFCGLVLDYNEDTKIATIQQRNNFKPGQEIEFFGPEIETFTQVVEAIYDEEGNSLDAARHPLQIVQIKVDRPIYPNNMMRKEIG
>NZ_AP019751.1|WP_000648617.1|1755321_1755945_-|uridine-kinase
MKATTIIGIAGGSGSGKTTVTNEIMKNLEGHSVALLAQDYYYKDQKHLTFDERLETNYDHPFAFDNDLLIENLKDLKNGKAVEVPTYDYASHTRSDITIDFKPKDVIIVEGIFALENKVLRDMMDVKIYVDTDADLRILRRLTRDTKERGRSMDSVINQYLSVVRPMHDQFIEPTKKYADIIIPEGGSNKVAIDIMTTKIQSLVSKQ
>NZ_AP019751.1|WP_000066094.1|1766852_1767971_-|tRNA-2-thiouridine(34)-synthase-MnmA
MSNKDIRVVVGMSGGVDSSVTAHVLKEQGYDVIGIFMKNWDDTDENGVCTATEDYNDVIEVCNQIGIPYYAVNFEKEYWDKVFTYFLDEYKKGRTPNPDVMCNKEIKFKAFLDHAMNLGADYVATGHYARIHRHEDGHVEMLRGVDNNKDQTYFLNQLSQQQLSKVMFPIGDIEKIEVRRIAEEQGLVTAKKKDSTGICFIGEKNFKTFLSQYLPAQPGDMITLDGKKMGKHSGLMYYTIGQRHGLGIGGDGDPWFVVGKNLKDNVLYVEQGFHHDALYSDYLIASDYSFVNPEDNDLDQGFECTAKFRYRQKDTKVFVKRENDHALRVTFAEPVRAITPGQAVVFYQGDVCLGGATIDDVFKNEGQLNYVV
>NZ_AP019751.1|WP_000409158.1|1767971_1769114_-|cysteine-desulfurase
MEIYADYAATTPVKPEVVDAMMMIYNSHYGNPSSIHAKGRDARKYLDESRRQIAQLLGADTHEIIFTSGATESNNTAIKGIVKANEQLGNHIITSKIEHHSVLHVFEQLEREGFDVTYLDVDDTGAIDLDQLEETITDKTILVSIMFVNNEVGTVQQIYDIQDIIAETNAYFHVDAVQAIGHLDVKFDEFEIDAMSITAHKFGGPKGVGALLVKDHVTLDYPQLGGEQELKRRAGTENLAQIVGMAKALQLAEKNRDDNNIHLMNLKEQFLVKLQERAIPFELNGSMTDATGHIVNLYFPFVEVETMLTLLDMAQIYVSSGSACTAGSTQPSHVLDAMFEDEERSNHSIRFSFNELTTENEINAIVAEIHKIYFKFKEES
>NZ_AP019751.1|WP_000985895.1|1769425_1770439_+|LLM-class-flavin-dependent-oxidoreductase
MAIKYSALNLVPIREGEDERTAINDMVKLAQHLDELSYERYWIAEHHNAPNLVSSATALLIQHTLEHTKHIRVGSGGIMLPNHAPLIVAEQFGTMATLFPNRVDLGLGRAPGTDMMTASALRRDQHDGVYKFPEEVSLLQQYFGPAHQQAYVRAYPAVGKNVPLYILGSSTDSAHLAARKGLPYVFAGHFAPQQMKEAIEIYKTLFEPSDVLDEPYVIVCLNTIVAENDDEAQYLASSMAQVMVSITRGRMQPVQPPTHELQNILTPREYAMAMERQKISLIGSENTVQQKIQDFMETYGEVNEIMAISYIYDKDMQLDSYRRFKNVINQINEKNTL
>NZ_AP019751.1|WP_000009238.1|1770675_1770822_-|hypothetical-protein
MSFMDKAKDAVEKFKNSDNEQVKNVKDKINEYTGSNNEEKKENEDKEK
>NZ_AP019751.1|WP_000752909.1|1770861_1771044_-|CsbD-family-protein
MADESKFDQFKGNVKETVGNVTDNKELEKEGQQDKATGKAKEVVENAKNKITDAIDKLKK
>NZ_AP019751.1|WP_000704122.1|1771143_1771566_-|Rrf2-family-transcriptional-regulator
MKISTKGRYGLTLMISLAKKEGQGCISLKSIAEENNLSDLYLEQLVGPLRNAGLIRSVRGAKGGYQLRVPAEEISAGDIIRLLEGPITFVESIESEPPAQKQLWIRMRDAVRDVLDNTTLKYLAEYVDTSEDLDGYMFYI
>NZ_AP019751.1|WP_000102740.1|1771650_1772925_+|replication-associated-recombination-protein-A
MSTEPLASRMRPKNIDEIISQQHLVGPRGIIRRMVDTKKLTSMIFYGPPGIGKTSIAKAISGSTQYKFRQLNAVTNTKKDMQLVVEEAKMSGQVILLLDEIHRLDKAKQDFLLPHLENGKIVLIGATTSNPYHAINPAIRSRAQIFELYPLNDEDVRQALTRAIEDEENGLKTYQPKIDEDAMTYFSTQSQGDVRSALNALELAVLSADNDKDGYRHVTLQDAKDCLQKGAFVSDKDGDMHYDVMSAFQKSIRGSDVNAALHYLARLIEAGDLPTIVRRLLVISYEDIGLASPNAGQRTLAAIESAERLGLPEARIPLSQAVIELCLSPKSNSAMSAIDSALSDIRNGHVGQIPNHLKDGHYQGAKDLGRSIGYKYPHQYVNGYVSQQYLPDKLKNKIYYEPKTTSKSEQQLKEIYNNLLKQRP
>NZ_AP019751.1|WP_000682646.1|1773085_1773859_-|tRNA-threonylcarbamoyladenosine-dehydratase
MKHQFSRNELAIGQQGLDLLKQQTVVILGVGGVGSFAAEALARTNIGHIILIDKDDVDITNVNRQLHALTTTVGQSKVSLMEERIKLINPDCKVTPLHMFYTEETYEEIFDNYDIDYFVDASDTIMYKVHLMKECLDRGIKVISSMGAANKTDPTRFTISDISKTHTDPMAKIIRQKLKKLGIRKGIPVVFSDESPIVIREDVKDIVGDKNAINRKGQMPPSSNAFVPSVVGLICASYVVNDVLKDIPVRRIKDKGQ
>NZ_AP019751.1|WP_001790559.1|1773858_1773987_-|hypothetical-protein
MGFIAFNKCFLVEFWENNQSDNAKYKILSYYVLMYKSVKEVK
>NZ_AP019751.1|WP_000044799.1|1774319_1776086_-|aspartate--tRNA-ligase
MSKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDREGIVQVVFNPAFSEEALKIAETVRSEYVVEVQGTVTKRDPETVNPKIKTGQVEVQVTNIKVINKSETPPFSINEENVNVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDDEGFFDIETPVLTKSTPEGARDYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQIVKCFRDEDLRADRQPEFTQVDIEMSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPRMTYKEAMRRYGSDKPDTRFEMELIDVSQLGRDMDFKVFKDTVENDGEIKAIVAKGAAEQYTRKDMDALTEFVNIYGAKGLAWVKVVEDGLTGPIGRFFETENVETLLTLTGAEAGDLVMFVADKPNVVAQSLGALRVKLAKELGLIDETKLNFLWVTDWPLLEYDEDAKRYVAAHHPFTSPKEADIAKLGTAPEEAEANAYDIVLNGYELGGGSIRIHDGELQEKMFEVLGFTKEQAQEQFGFLLDAFKYGAPPHGGIALGLDRLVMLLTNRTNLRDTIAFPKTASATCLLTNAPGEVSDKQLEELSLRIRH

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Crispr_ID: NZ_AP019751_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019751_8

2184161-2184249

Orphan

Consensus_repeat	Method
GTTTTTGACTGACTTCTCAATCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP019751_8

>merge|NZ_AP019751|8|2184161-2184249|CRISPRCasFinder
GTTTTTGACTGACTTCTCAATCAATTTATAACTTTATTATACATAATTGTTTTTCTTTTGCAATAGTTTTTCGACTGACTTCTCAATCA

>NZ_AP019751|8|7|2184161-2184249|CRISPRCasFinder
GTTTTTGACTGACTTCTCAATCA	ATTTATAACTTTATTATACATAATTGTTTTTCTTTTGCAATAG
TTTTTCGACTGACTTCTCAATCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019751.1\|WP_000481967.1\|2183602_2183920_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|200128
NZ_AP019751.1\|WP_017431962.1\|2182572_2182893_-\|DUF1474-family-protein	unknown	unknown	gnl\|CDD\|369323
NZ_AP019751.1\|WP_000153640.1\|2183924_2184143_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NZ_AP019751.1\|WP_000120305.1\|2189163_2190423_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223021
NZ_AP019751.1\|WP_000708436.1\|2183459_2183606_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_117225041.1\|2181636_2182506_-\|primase-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|214926
NZ_AP019751.1\|WP_000356927.1\|2179212_2179593_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_000620857.1\|2184315_2184990_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188
NZ_AP019751.1\|WP_000197635.1\|2188395_2189139_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_AP019751.1\|WP_017431963.1\|2182893_2183253_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_001823225.1\|2192990_2193125_-\|delta-lysin-family-phenol-soluble-modulin	unknown	unknown	gnl\|CDD\|173213
NZ_AP019751.1\|WP_001058497.1\|2183254_2183467_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_001105705.1\|2193360_2193924_+\|accessory-gene-regulator-AgrB	unknown	unknown	gnl\|CDD\|214819
NZ_AP019751.1\|WP_000522384.1\|2190619_2191246_+\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|226090
NZ_AP019751.1\|WP_000867941.1\|2191606_2192392_+\|carbon-nitrogen-family-hydrolase	unknown	unknown	gnl\|CDD\|143607
NZ_AP019751.1\|WP_000240642.1\|2186244_2187861_-\|chaperonin-GroEL	unknown	unknown	gnl\|CDD\|234573
NZ_AP019751.1\|WP_000917289.1\|2187936_2188221_-\|co-chaperone-GroES	unknown	unknown	gnl\|CDD\|178988
NZ_AP019751.1\|WP_144078998.1\|2185003_2186176_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271189
NZ_AP019751.1\|WP_144078996.1\|2178574_2179216_-\|pathogenicity-island-protein	unknown	unknown	gnl\|CDD\|374630
NZ_AP019751.1\|WP_144078997.1\|2179922_2181623_-\|DUF927-domain-containing-protein	unknown	unknown	gnl\|CDD\|227806

Protein	Function_ID	Function_description	E-value
NZ_AP019751.1\|WP_000481967.1\|2183602_2183920_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|200128	TIGR01764, Probable_excisionase, DNA binding domain, excisionase family. An excisionase, or Xis protein, is a small protein that binds and promotes excisive recombination; it is not enzymatically active. This model represents a number of putative excisionases and related proteins from temperate phage, plasmids, and transposons, as well as DNA binding domains of other proteins, such as a DNA modification methylase. This model identifies mostly small proteins and N-terminal regions of large proteins, but some proteins appear to have two copies. This domain appears similar, in both sequence and predicted secondary structure (PSIPRED) to the MerR family of transcriptional regulators (pfam00376). [Unknown function, General].	5.89089e-17
NZ_AP019751.1\|WP_017431962.1\|2182572_2182893_-\|DUF1474-family-protein	gnl\|CDD\|369323	pfam07342, DUF1474, Protein of unknown function (DUF1474). This family consists of several bacterial proteins of around 100 residues in length. Members of this family seem to be found exclusively in Staphylococcus aureus. The function of this family is unknown.	1.33418e-26
NZ_AP019751.1\|WP_000153640.1\|2183924_2184143_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	9.85461e-11
NZ_AP019751.1\|WP_000120305.1\|2189163_2190423_-\|hypothetical-protein	gnl\|CDD\|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	1.4094e-08
NZ_AP019751.1\|WP_117225041.1\|2181636_2182506_-\|primase-C-terminal-domain-containing-protein	gnl\|CDD\|214926	smart00942, PriCT_1, Primase C terminal 1 (PriCT-1). This alpha helical domain is found at the C terminal of primases.	1.31701e-15
NZ_AP019751.1\|WP_000620857.1\|2184315_2184990_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.58614e-10
NZ_AP019751.1\|WP_000197635.1\|2188395_2189139_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.67124e-11
NZ_AP019751.1\|WP_001823225.1\|2192990_2193125_-\|delta-lysin-family-phenol-soluble-modulin	gnl\|CDD\|173213	PRK14752, PRK14752, delta-lysin family phenol-soluble modulin.	4.75617e-14
NZ_AP019751.1\|WP_001105705.1\|2193360_2193924_+\|accessory-gene-regulator-AgrB	gnl\|CDD\|214819	smart00793, AgrB, Accessory gene regulator B. The accessory gene regulator (agr) of Staphylococcus aureus is the central regulatory system that controls the gene expression for a large set of virulence factors. The arg locus consists of two transcripts: RNAII and RNAIII. RNAII encodes four genes (agrA, B, C, and D) whose gene products assemble a quorum sensing system. At low cell density, the agr genes are continuously expressed at basal levels. A signal molecule, autoinducing peptide (AIP), produced and secreted by the bacteria, accumulates outside of the cells. When the cell density increases and the AIP concentration reaches a threshold, it activates the agr response, i.e. activation of secreted protein gene expression and subsequent repression of cell wall-associated protein genes. AgrB and AgrD are essential for the production of the autoinducing peptide which functions as a signal for quorum sensing. AgrB is a transmembrane protein. AgrB is involved in the proteolytic processing of AgrD and may have both proteolytic enzyme activity and a transporter facilitating the export of the processed AgrD peptide.	1.24601e-53
NZ_AP019751.1\|WP_000522384.1\|2190619_2191246_+\|nitroreductase-family-protein	gnl\|CDD\|226090	COG3560, FMR2, Predicted oxidoreductase related to nitroreductase [General function prediction only].	5.71771e-116
NZ_AP019751.1\|WP_000867941.1\|2191606_2192392_+\|carbon-nitrogen-family-hydrolase	gnl\|CDD\|143607	cd07583, nitrilase_5, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	1.52436e-125
NZ_AP019751.1\|WP_000240642.1\|2186244_2187861_-\|chaperonin-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NZ_AP019751.1\|WP_000917289.1\|2187936_2188221_-\|co-chaperone-GroES	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	5.94304e-45
NZ_AP019751.1\|WP_144078997.1\|2179922_2181623_-\|DUF927-domain-containing-protein	gnl\|CDD\|227806	COG5519, COG5519, Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair].	1.69929e-165
NZ_AP019751.1\|WP_144078996.1\|2178574_2179216_-\|pathogenicity-island-protein	gnl\|CDD\|374630	pfam16560, SAPI, Putative mobile pathogenicity island. SAPI is a family of putative Gram-positive mobile pathogenicity island proteins. SAPIs are responsible for many superantigen-related diseases in humans as they carry two or more superantigens.	1.58661e-113
NZ_AP019751.1\|WP_144078998.1\|2185003_2186176_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	3.86816e-47

>NZ_AP019751.1|WP_000153640.1|2183924_2184143_-|helix-turn-helix-transcriptional-regulator
MTILANTRKFKEAMFLKGFNLSDLSRETGVGISYLSQIINGKKIPSPKLAKKMAEVLQVEVNELFEFEVKEA
>NZ_AP019751.1|WP_000481967.1|2183602_2183920_-|helix-turn-helix-domain-containing-protein
MFNINIDEDEARELLEQAINARVDELAKEKYFMTYKELSNYLNLSKPTIEELLINNGMKYYMVGSTYRFKKSDVDEFMEQLTAHMNIQNNDFKQVNIKKLLEARQ
>NZ_AP019751.1|WP_000708436.1|2183459_2183606_-|hypothetical-protein
MKIYLTYICLVSLLTILLLAISNMYVAFSVYGMMVTYGFNLTGGLENE
>NZ_AP019751.1|WP_001058497.1|2183254_2183467_-|hypothetical-protein
MNNEQKEVIKDIYSSLESVANNKSEVYIHEFKCGEKEWTETVNREQHLQAIIEWTLQQIENNFEFEEENE
>NZ_AP019751.1|WP_017431963.1|2182893_2183253_-|hypothetical-protein
MNKLTKQEYKNIENKLNYEHMVNGKKRTNKINKLLQREHDRDASIIKSEYPRLSDSEISEVIVDYRTYKKLVIATETFVDFPINYEDSNVCQFITKEDIEDLKVAIEEMTSFVENLEEL
>NZ_AP019751.1|WP_017431962.1|2182572_2182893_-|DUF1474-family-protein
MNWEIRNLMCNIEIVKEKLEDVATTHTWFVDERFRKRSLKTKEEAVNYGLAYNEHRIHNEQVTELMLTYLKELDGLMNKFHEIEKASSDVSLATESDDAKKLKITE
>NZ_AP019751.1|WP_117225041.1|2181636_2182506_-|primase-C-terminal-domain-containing-protein
MNEIKLEYDTHVSVVHYESLDSRSFKSFSKPEWSKLVNKLSVPIEANYKYARGVAVYGDIKDGANDHGETIKKHRNDVNVIYRDVIVLDYDEINDLKQLHEAISSVLSSVAWYWHTSFSHTTEQARIRLYIPLNERISADDYRKYTKVLANKIGHKVDEGSYQPSRCFALPVIQKGHIFIKRVNDCPIMNVDMLEQWSKEFEQSNASPNVIGYTRRDSEYWRELCFGTTEGNRNNALASLIGHLLRCHVSDYIVYSFALLWGQFACKPPMKEQEINATFQSILNKHYNN
>NZ_AP019751.1|WP_144078997.1|2179922_2181623_-|DUF927-domain-containing-protein
METGKSDVLDKIEKINKKDSALQEIIPKGYEIEHHQCGVALYQLIPSKKEGEPDKKVFITNTIPQITERFEDIESNEVSFNMLFYDNKTPVNIAVSAEEISDSRQLLKLVNKKLDVTSSTSTKLVDYINVSKRYNPPLNVKVATRLGHVKGYFIYPYQEVMKDSNIKLFSNDKGFQKLIDSFQSKGTLEGYSKKVFGQIKDLPMVMVMLYASLGSVLLREFGLQPFIVEISGSTSTGKTFTLNLVSSVWGTSDLITTWSSTQNSIESMASFLNSFPMFKDDTRNTHPKFVTSATYNFSSGESKSRSNINLTLNAKKEWRNILISTGESSIANMADEKAGVSARVVTLQDQPYPDNFDFTTLDKSFRENYGTLGLAFIKQYVSKKDVYKNAFESYQRYFNQKGSNEIMQRLGRAFALLQVTGEVLNDIDGFEHDHFKIIEQTYDSMVKNNKTIDKPKQLLEELLQYLDANRNNIAGDGYSSVKNGDTKAIYKRDYLCILGQTVYDKLGHEMQTITGQWDKKGYLITSKDRIQKEVRFNSQKNRGYAIKDEIIKELGFDFSNSHNPYN
>NZ_AP019751.1|WP_000356927.1|2179212_2179593_-|hypothetical-protein
MDKEQLKKYIYDYVKEYKEIPIYQLEDLFKEINHDYIGRTSITHDKDENVVFWSGWNKITMFALIELVKSEQLDLVYRGSFVMRYLLDGRVPNLPLAICYPEDGQQTDVLSWVPMVLRINKEEKIK
>NZ_AP019751.1|WP_144078996.1|2178574_2179216_-|pathogenicity-island-protein
MNIETIVNEFETRAGTLLRYYTGLLEHSKVQPCCFKLYNDPFDMVYVVMNNKLFGHVYIKDCKVRKSFELASPKHTEGLIRSIEGHYVGYELHDGKQLSISDMMASHLFEDEYFMYGLQTYAESNNSDVFEYLENGFDTDTLEGIQSSNTDVIANIEMLYQIATGINEPAPELVEGLKLVTEFVQDEKATQEDYKALERKLTELKSSYYSLNK
>NZ_AP019751.1|WP_000620857.1|2184315_2184990_+|helix-turn-helix-transcriptional-regulator
MIRNRLSELLSERGLKISRVAKDVKIARSSLTSMAQNDSEMIRYDAIDKLCSYLHISPSEFFEHNPINFDFTFDEEPNYKINDVFEGFEVTANITHAFSIENFDFEILVDVELDNRQKLNFDLDVSYKETEKITNSQHRFIFTIKNEDENIGLKKYVDSLSAGLKNLLFKKINQKLSGYVSEIIVKNIDDIEELFPNKGEKSTTLHKEILQTDSRLSSDIFKEY
>NZ_AP019751.1|WP_144078998.1|2185003_2186176_+|tyrosine-type-recombinase/integrase
MASYEKRGNTWRYRISLGKDAETGKYKYISNSGFKRKSDAKHHAEMVERQLRNGDYIAPSTSTFKQVADDWISQYANEVKVSSVRAREKAINHAIERFNNKPIQTINKHEYQRFVNDISAQYSKNYVDSIIASTNMMFKYAYDMKLIRIMPSEGIKRPKKKISVEELEDTEIHKKFLEKDELFQFLEVAKNHHSPQNSFEVFCTLAYTGMRAGELLALKWSDIDFENNTINITKTYYNPNNNKKQFQILTPKTESSIGKISVDPHVIKLLKNYKVDVQDTWKNELYVDNNFVFTDVNGYPLVIKKLQLWIKAILKKTDITNKQISTHSFRHTHCALLIEAGVHIKEIQERLRHKDINTTMNIYAKITNSYKKDASQKFSKLMENVSKDLF
>NZ_AP019751.1|WP_000240642.1|2186244_2187861_-|chaperonin-GroEL
MVKQLKFSEDARQAMLRGVDQLANAVKVTIGPKGRNVVLDKEFTAPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGLRQGIDKAVKVAVEALHENSQKVENKNEIAQVGAISAADEEIGRYISEAMEKVGNDGVITIEESNGLNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYILVTDKKISSFQDILPLLEQVVQSNRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGAQVITDDLGLDLKDASIDMLGTASKVEVTKDNTTVVDGDGDENSIDARVSQLKSQIEETESDFDREKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVNVYQKVSEIEAEGDIETGVNIVLKALTAPVRQIAENAGLEGSVIVERLKNAEPGVGFNAATNEWVNMLEAGIVDPTKVTRSALQHAASVAAMFLTTEAVVASIPEKNNDQPNMGGMPGMM
>NZ_AP019751.1|WP_000917289.1|2187936_2188221_-|co-chaperone-GroES
MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGTGRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
>NZ_AP019751.1|WP_000197635.1|2188395_2189139_+|CPBP-family-intramembrane-metalloprotease
MTRLWASLLTVIIYILSQFLPLLIVKKLPFVQYSGIELTKAVIYIQLVLFLIAATTIILINLKIKNPTKLELEVKEPKKYIIPWALLGFALVMIYQMVVSIVLTQIYGGQQVSPNTEKLIIIARKIPIFIFFVSIIGPLLEEYVFRKVIFGELFNAIKGNRIVAFIIATTVSSLIFALAHNDFKFIPVYFGMGVIFSLAYVWTKRLAVPIIIHMLQNGFVVIFQLLNPEALKKATEQANFIYHIFIP
>NZ_AP019751.1|WP_000120305.1|2189163_2190423_-|hypothetical-protein
MSYHWFKKMLLSTSILILSSSSLGLATHTVEAKDNLNGEKPTTNLNHNITSPSVNSEMNNNETGTPHESNQTGNEGTGSNSRDANPDSNNVKPDSNNQNPSTDSKPDPNNQNPSPNPKPDPDNPKPKPDPKPDPDKPKPNPDPKPDPDNPKPNPDPKPDPDKPKPNPDPKPDPDKPKPNPNPKPDPNKPNPNPSPDPDQPGDSNHSGGSKNGGTWNPNASDGSNQGQWQPNGNQGNSQNPTGNDFVSQRFLALANGAYKYNPYILNQINKLGKDYGEVTDEDIYNIIRKQNFSGNAYLNGLQQQSNYFRFQYFNPLKSERYYRNLDEQVLALITGEIGSMPDLKKPEDKPDSKQRSFEPHEKDDFTVVKKQEDNKKSASTAYSKSWLAIVCSMMVVFSIMLFLFVKRNKKKNKNESQRR
>NZ_AP019751.1|WP_000522384.1|2190619_2191246_+|nitroreductase-family-protein
MGLFKKDKKAMTFDNAMEERRSIYNLKDSISISDDELESMIAHAVKHVPSSFNSQSTRIVLLLNDNNNKFWDNTKAILKEVMGENRDFEPTEQKIDNFKHSYGTILFYEDQDVVSGLQEQMPNYYDNFAIWSTQTNAMHQFAIWTALATKGIGASLQHYNPLVDEMTSNEFNIPKSWKLIAQMPFGDIREAAGEKTFNPVEDRFVIKK
>NZ_AP019751.1|WP_000867941.1|2191606_2192392_+|carbon-nitrogen-family-hydrolase
MKVQIYQLPIIFGDSSKNEAQITQWFEKNMNAEVDVVVLPEMWNNGYDLEHLNEKADNNLGQSFSFIKHLAEKYKVDIVAGSVSNIRNYQIFNTAFSVNKSGQLINEYDKVHLVPMLREHEFLTAGENVAEPFQLSDGTYVTQLICYDLRFPELLRYPARSGAKIAFYVAQWPMSRLQHWHSLLKARAIENNMFVIGTNSTGFDGNTEYAGHSIVINPNGDLVGELNESADILTVDLNLNEVEQQRENIPIFKSIKLDLYK
>NZ_AP019751.1|WP_001823225.1|2192990_2193125_-|delta-lysin-family-phenol-soluble-modulin
MSCLILRIFILIKEGVISMAQDIISTISDLVKWIIDTVNKFTKK
>NZ_AP019751.1|WP_001105705.1|2193360_2193924_+|accessory-gene-regulator-AgrB
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQVLAKNIGKLIVMYTIAYILNIFIFTLITNISFYLIRRYAHGAHAPSSFWCYIESITLFIVLPLLVLHFHINETLMMFLALISVGVVIKYAPAATKKKPIPARLVKQKRYFSIIISTILFIITLFVKEPYTQFIQLGIIIQAITLLPIYYSKED

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Crispr_ID: NZ_AP019751_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019751_9

2311375-2311455

Orphan

Consensus_repeat	Method
CAACTTTAGTTGTTAGGGGCTCTT	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NZ_AP019751_9

>merge|NZ_AP019751|9|2311375-2311455|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTCAACTTTAGTTGTTAGGGGCTTCT

>NZ_AP019751|9|8|2311375-2311455|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTT	ATGCATGCGCTTAGCGCAGGCGCTCCTACTTTT
CAACTTTAGTTGTTAGGGGCTTCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019751.1\|WP_000648723.1\|2321967_2323074_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_AP019751.1\|WP_001292149.1\|2321533_2321968_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_AP019751.1\|WP_000927361.1\|2319389_2321522_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_AP019751.1\|WP_000160304.1\|2301856_2302567_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NZ_AP019751.1\|WP_001127960.1\|2306507_2307446_-\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
NZ_AP019751.1\|WP_000808817.1\|2306246_2306477_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_001024095.1\|2307881_2308547_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
NZ_AP019751.1\|WP_000083807.1\|2317816_2319355_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_AP019751.1\|WP_000019743.1\|2309020_2310001_+\|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl\|CDD\|224151
NZ_AP019751.1\|WP_000495683.1\|2310266_2311358_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_001792784.1\|2312574_2312733_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_001802298.1\|2311790_2311895_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_000908178.1\|2314316_2315099_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_AP019751.1\|WP_000521495.1\|2331184_2332540_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NZ_AP019751.1\|WP_000070866.1\|2302687_2303131_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
NZ_AP019751.1\|WP_000334465.1\|2315330_2317136_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_AP019751.1\|WP_000370917.1\|2313391_2314249_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_AP019751.1\|WP_001123300.1\|2303330_2303744_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NZ_AP019751.1\|WP_000123402.1\|2304201_2305575_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
NZ_AP019751.1\|WP_000003759.1\|2308698_2309019_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042

Protein	Function_ID	Function_description	E-value
NZ_AP019751.1\|WP_000648723.1\|2321967_2323074_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_AP019751.1\|WP_000927361.1\|2319389_2321522_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	1.10767e-67
NZ_AP019751.1\|WP_000160304.1\|2301856_2302567_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
NZ_AP019751.1\|WP_001127960.1\|2306507_2307446_-\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
NZ_AP019751.1\|WP_001024095.1\|2307881_2308547_-\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.27122e-47
NZ_AP019751.1\|WP_000083807.1\|2317816_2319355_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_AP019751.1\|WP_000019743.1\|2309020_2310001_+\|CDF-family-zinc-efflux-transporter-CzrB	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.20197e-108
NZ_AP019751.1\|WP_001292149.1\|2321533_2321968_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_AP019751.1\|WP_000908178.1\|2314316_2315099_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	9.14849e-105
NZ_AP019751.1\|WP_000521495.1\|2331184_2332540_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NZ_AP019751.1\|WP_000070866.1\|2302687_2303131_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
NZ_AP019751.1\|WP_000334465.1\|2315330_2317136_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_AP019751.1\|WP_000370917.1\|2313391_2314249_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	7.97122e-60
NZ_AP019751.1\|WP_001123300.1\|2303330_2303744_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	4.46591e-45
NZ_AP019751.1\|WP_000123402.1\|2304201_2305575_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
NZ_AP019751.1\|WP_000003759.1\|2308698_2309019_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17

>NZ_AP019751.1|WP_000495683.1|2310266_2311358_+|hypothetical-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYVQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPVFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>NZ_AP019751.1|WP_000019743.1|2309020_2310001_+|CDF-family-zinc-efflux-transporter-CzrB
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHAH
>NZ_AP019751.1|WP_000003759.1|2308698_2309019_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>NZ_AP019751.1|WP_001024095.1|2307881_2308547_-|SDR-family-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGEQDIKDALTQFEIEKD
>NZ_AP019751.1|WP_001127960.1|2306507_2307446_-|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>NZ_AP019751.1|WP_000808817.1|2306246_2306477_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>NZ_AP019751.1|WP_000123402.1|2304201_2305575_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>NZ_AP019751.1|WP_001123300.1|2303330_2303744_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDCIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>NZ_AP019751.1|WP_000070866.1|2302687_2303131_-|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>NZ_AP019751.1|WP_000160304.1|2301856_2302567_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>NZ_AP019751.1|WP_001802298.1|2311790_2311895_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NZ_AP019751.1|WP_001792784.1|2312574_2312733_+|hypothetical-protein
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>NZ_AP019751.1|WP_000370917.1|2313391_2314249_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASPYTKDVINRLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>NZ_AP019751.1|WP_000908178.1|2314316_2315099_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKKISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATSGTVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDEEVRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPMLAMIYVTHFIEEITSNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_AP019751.1|WP_000334465.1|2315330_2317136_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_AP019751.1|WP_000083807.1|2317816_2319355_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_AP019751.1|WP_000927361.1|2319389_2321522_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDIDGNTSFENEQTSYLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDAINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMVLITVLEEPLILPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NZ_AP019751.1|WP_001292149.1|2321533_2321968_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_AP019751.1|WP_000648723.1|2321967_2323074_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NZ_AP019751.1|WP_000521495.1|2331184_2332540_-|phosphoglucosamine-mutase
MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK

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Crispr_ID: NZ_AP019751_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019751_10

2323697-2323783

Orphan

Consensus_repeat	Method
GCCAACTGATGTTTGCGTATCATTAGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP019751_10

>merge|NZ_AP019751|10|2323697-2323783|CRISPRCasFinder
GCCAACTGATGTTTGCGTATCATTAGTTTGCATATCTTTAGCTTTATTGTTTGCAACTGAGCCAACTGATGTTTGCATATCATTAGT

>NZ_AP019751|10|9|2323697-2323783|CRISPRCasFinder
GCCAACTGATGTTTGCGTATCATTAGT	TTGCATATCTTTAGCTTTATTGTTTGCAACTGA
GCCAACTGATGTTTGCATATCATTAGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019751.1\|WP_000884735.1\|2347372_2348560_-\|UDPGP-type-1-family-protein	unknown	unknown	gnl\|CDD\|133036
NZ_AP019751.1\|WP_000927361.1\|2319389_2321522_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_AP019751.1\|WP_000958531.1\|2341601_2342666_-\|P-loop-NTPase	unknown	unknown	gnl\|CDD\|378455
NZ_AP019751.1\|WP_001237503.1\|2345150_2346494_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_AP019751.1\|WP_001141006.1\|2342813_2344256_-\|multidrug-efflux-MFS-transporter-LmrS	unknown	unknown	gnl\|CDD\|129794
NZ_AP019751.1\|WP_000047255.1\|2346670_2347354_-\|hemolysin-III-family-protein	unknown	unknown	gnl\|CDD\|224191
NZ_AP019751.1\|WP_001793373.1\|2344578_2345052_-\|multidrug-efflux-transporter-SepA	unknown	unknown	gnl\|CDD\|374975
NZ_AP019751.1\|WP_000083807.1\|2317816_2319355_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_AP019751.1\|WP_000648723.1\|2321967_2323074_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_AP019751.1\|WP_000495683.1\|2310266_2311358_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_001792784.1\|2312574_2312733_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_000894032.1\|2332566_2333499_-\|YbbR-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|227193
NZ_AP019751.1\|WP_001802298.1\|2311790_2311895_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_000908178.1\|2314316_2315099_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_AP019751.1\|WP_000521495.1\|2331184_2332540_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NZ_AP019751.1\|WP_000347896.1\|2333500_2334310_-\|TIGR00159-family-protein	unknown	unknown	gnl\|CDD\|224539
NZ_AP019751.1\|WP_000167873.1\|2334498_2335407_-\|arginase	unknown	unknown	gnl\|CDD\|212515
NZ_AP019751.1\|WP_000334465.1\|2315330_2317136_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_AP019751.1\|WP_000370917.1\|2313391_2314249_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_AP019751.1\|WP_001292149.1\|2321533_2321968_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014

Protein	Function_ID	Function_description	E-value
NZ_AP019751.1\|WP_000927361.1\|2319389_2321522_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	1.10767e-67
NZ_AP019751.1\|WP_000958531.1\|2341601_2342666_-\|P-loop-NTPase	gnl\|CDD\|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	6.43129e-115
NZ_AP019751.1\|WP_000884735.1\|2347372_2348560_-\|UDPGP-type-1-family-protein	gnl\|CDD\|133036	cd04193, UDPGlcNAc_PPase, UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc) pyrophosphorylase (UAP) (also named GlcNAc1P uridyltransferase), catalyzes the reversible conversion of UTP and GlcNAc1 to PPi and UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc), the activated form of GlcNAc, is a key precursor of N- and O-linked glycosylations. It is essential for the synthesis of chitin (a major component of the fungal cell wall) and of the glycosylphosphatidylinositol (GPI) linker which anchors a variety of cell surface proteins to the plasma membrane. In bacteria, UDPGlcNAc represents an essential precursor for both peptidoglycan and lipopolysaccharide biosynthesis. Human UAP has two isoforms, resulting from alternative splicing of a single gene and differing by the presence or absence of 17 amino acids. UDPGlcNAc pyrophosphorylase shares significant sequence and structure conservation with UDPglucose pyrophosphorylase.	2.43588e-149
NZ_AP019751.1\|WP_001237503.1\|2345150_2346494_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	2.27036e-43
NZ_AP019751.1\|WP_000047255.1\|2346670_2347354_-\|hemolysin-III-family-protein	gnl\|CDD\|224191	COG1272, COG1272, Predicted membrane protein, hemolysin III homolog [General function prediction only].	2.41003e-66
NZ_AP019751.1\|WP_001793373.1\|2344578_2345052_-\|multidrug-efflux-transporter-SepA	gnl\|CDD\|374975	pfam17080, SepA, Multidrug Resistance efflux pump. SepA is a drug efflux protein that is involved in bacterial multidrug resistance. It is predicted to have four transmembrane domains.	3.24535e-30
NZ_AP019751.1\|WP_000083807.1\|2317816_2319355_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_AP019751.1\|WP_000648723.1\|2321967_2323074_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_AP019751.1\|WP_001141006.1\|2342813_2344256_-\|multidrug-efflux-MFS-transporter-LmrS	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.08461e-81
NZ_AP019751.1\|WP_000347896.1\|2333500_2334310_-\|TIGR00159-family-protein	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	2.13611e-103
NZ_AP019751.1\|WP_000908178.1\|2314316_2315099_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	9.14849e-105
NZ_AP019751.1\|WP_000521495.1\|2331184_2332540_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NZ_AP019751.1\|WP_000894032.1\|2332566_2333499_-\|YbbR-like-domain-containing-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	6.26423e-118
NZ_AP019751.1\|WP_000167873.1\|2334498_2335407_-\|arginase	gnl\|CDD\|212515	cd09989, Arginase, Arginase family. This family includes arginase, also known as arginase-like amidino hydrolase family, and related proteins. Arginase is a binuclear Mn-dependent metalloenzyme and catalyzes hydrolysis of L-arginine to L-ornithine and urea (Arg, EC 3.5.3.1), the reaction being the fifth and final step in the urea cycle, providing the path for the disposal of nitrogenous compounds. Arginase controls cellular levels of arginine and ornithine which are involved in protein biosynthesis, and in production of creatine, polyamines, proline and nitric acid. In vertebrates, at least two isozymes have been identified: type I (ARG1) cytoplasmic or hepatic liver-type arginase and type II (ARG2) mitochondrial or non-hepatic arginase. Point mutations in human arginase ARG1 gene lead to hyperargininemia with consequent mental disorders, retarded development and early death. Hyperargininemia is associated with a several-fold increase in the activity of the mitochondrial arginase (ARG2), causing persistent ureagenesis in patients. ARG2 overexpression plays a critical role in the pathophysiology of cholesterol mediated endothelial dysfunction. Thus, arginase is a therapeutic target to treat asthma, erectile dysfunction, atherosclerosis and cancer.	6.64002e-146
NZ_AP019751.1\|WP_000334465.1\|2315330_2317136_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_AP019751.1\|WP_000370917.1\|2313391_2314249_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	7.97122e-60
NZ_AP019751.1\|WP_001292149.1\|2321533_2321968_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62

>NZ_AP019751.1|WP_000648723.1|2321967_2323074_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NZ_AP019751.1|WP_001292149.1|2321533_2321968_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_AP019751.1|WP_000927361.1|2319389_2321522_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDIDGNTSFENEQTSYLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDAINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMVLITVLEEPLILPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NZ_AP019751.1|WP_000083807.1|2317816_2319355_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_AP019751.1|WP_000334465.1|2315330_2317136_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_AP019751.1|WP_000908178.1|2314316_2315099_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKKISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATSGTVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDEEVRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPMLAMIYVTHFIEEITSNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_AP019751.1|WP_000370917.1|2313391_2314249_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASPYTKDVINRLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>NZ_AP019751.1|WP_001792784.1|2312574_2312733_+|hypothetical-protein
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>NZ_AP019751.1|WP_001802298.1|2311790_2311895_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NZ_AP019751.1|WP_000495683.1|2310266_2311358_+|hypothetical-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYVQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPVFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>NZ_AP019751.1|WP_000521495.1|2331184_2332540_-|phosphoglucosamine-mutase
MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
>NZ_AP019751.1|WP_000894032.1|2332566_2333499_-|YbbR-like-domain-containing-protein
MLESKWGLRFIAFLLALFFFLSVNNVFGNIFNTGNLGQKSSKTIQDVPVEILYNTKDLHLTKAPETVNVTISGPQSKIIKIENPEDLRVVIDLSNAKAGKYQEKYQVKGLADDIHYSVKPKLANITLENKVTKKMTVQPDVSQSDIDPLYKITKQEVSPQTVKVTGGEEQLNDIAYLKATFKTNKKINGDTKDVAEVTAFDKKLNKLNVSIQPNEVNLQVKVEPFSKKVKVNVKQKGSLADDKELSSIDLEDKEIEIFGSRDDLQNISEVDAEVDLDGISESTEKTVKINLPEHVTKAQPSETKAYINVK
>NZ_AP019751.1|WP_000347896.1|2333500_2334310_-|TIGR00159-family-protein
MDFSNFFQNLSTLKIVTSILDLLIVWYVLYLLITVFKGTKAIQLLKGILVIVIGQQISMILNLTATSKLFDIVIQWGVLALIVIFQPEIRRALEQLGRGSFLKRYTSNTYSKDEEKLIQSVSKAVQYMAKRRIGALIVFEKETGLQDYIETGIAMDSNISQELLINVFIPNTPLHDGAMIIQGTKIAAAASYLPLSDSPKISKSLGTRHRAAVGISEVSDAFTVIVSEETGDISVTFDGKLRRDISNEIFEELLAEHWFGTRFQKKGVK
>NZ_AP019751.1|WP_000167873.1|2334498_2335407_-|arginase
MTKTKAIDIIGAPSTFGQRKLGVDLGPTAIRYAGLISRLKQLDLDVYDKGDIKVPVVNIEKFHSEQKGLRNYDEIIDVNQKLNKEVSASIENNRFPLVLGGDHSIAVGSVSAISKHYNNLGVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLELNSNVIKPENIVLIGMRDLDKGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKSRNVDGVHLSLDVDALDPLETPGTGTRVLGGLSYRESHFALELLHQSHLISSMDLVEVNPLIDSNNHTAEQAVSLVGTFFGETLL
>NZ_AP019751.1|WP_000958531.1|2341601_2342666_-|P-loop-NTPase
MLTVDQVKELVGEIKDPIIDVPLKETEGIVEVSIKEEKEHVSVKLAMAQLGGAPQLDLQMAVVNALKENGAKTVGIRFETLPEEKVNQFKPKEENKPKTIEGLLSQNNPVEFIAIASGKGGVGKSTVAVNLAVALAREGKKVGLVDADIYGFSVPDMMGIDEKPGIKGKEVIPVERHGVKVISMAFFVEENAPVIWRGPMLGKMLTNFFTEVKWGDIEYLILDLPPGTGDVALDVHTMLPSSKEIIVTTPHPTAAFVAARAGAMAKHTDHSILGVIENMSYFESKETGNKEYVFGKGGGTKLADELNTQLLGELPLEQPSWNPKDFAPSIYQSDDRLGKIYSSIAQKVIAATNK
>NZ_AP019751.1|WP_001141006.1|2342813_2344256_-|multidrug-efflux-MFS-transporter-LmrS
MAKVELTTRRRNFIVAVMLISAFVAILNQTLLNTALPSIMRELNINESTSQWLVTGFMLVNGVMIPLTAYLMDRIKTRPLYLAAMGTFLLGSIVAALAPNFGVLMLARVIQAMGAGVLMPLMQFTLFTLFSKEHRGFAMGLAGLVIQFAPAIGPTVTGLIIDQASWRVPFIIIVGIALVAFVFGLVSISSYNEVKYTKLDKRSVMYSTIGFGLMLYAFSSAGDLGFTSPIVIGALIISMVIIYLFIRRQFNITNALLNLRVFKNRTFALCTISSMIIMMSMVGPALLIPLYVQNSLSLSALLSGLVIMPGAIINGIMSVFTGKFYDKYGPRPLIYTGFTILTITTIMLCFLHTDTSYTYLIVVYAIRMFSVSLLMMPINTTGINSLRNEEISHGTAIMNFGRVMAGSLGTALMVTLMSFGAKIFLSTSPSHLTATEIKQQSIAIGVDISFAFVAVLVMAAYVIALFIREPKEIESNRRKF
>NZ_AP019751.1|WP_001793373.1|2344578_2345052_-|multidrug-efflux-transporter-SepA
MIVNYLKHKFYNLLTTMVVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIIFAVEHLMDYFRKMLPENAYFRGATFHLISYTVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
>NZ_AP019751.1|WP_001237503.1|2345150_2346494_-|MFS-transporter
MRLKSIITVIALILIMFMSAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPIVGELLSRFKIIYVAIAGLLLFSIGSFMCGLSTNFTMLIISRVIQGFGSGVLMSLSQIVPKLAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWHWLFYINIPIAIIAIILVIWTFHFPEEETVAKSKFDTKGLTLFYVFIGLIMFALLNQQLLLLNFLSFILAIVVAMCLFKVEKHVSSPFLPVVEFNRSITLVFITDLLTAICLMGFNLYIPVYLQEQLGLSPLQSGLVIFPLSLAWITLNFNLHRIEAKLSRKVIYLLSFTLLLVSSIIISFGIKLPVLIAFVLILAGLSFGYIYTKDSVIVQEETSPLQMKKMMSFYGLTKNLGASIGSTIMGYLYAIQSGIFGPNLHNVLSAVAVISIGLIVLWVVFFKEQSSQSKE
>NZ_AP019751.1|WP_000047255.1|2346670_2347354_-|hemolysin-III-family-protein
MSKSTKKSNDTIVETFKDIIPLSFGEEIGNAASHGVAALLTLLVLPYAAVHSYIAHGTLASVSMSIYVISIFMMFISSTIYHSMQNETPHKYILRIIDHSMIYVAISGTYTPILLTVVGGWIGWTVFILLWGTTLWGILYKSIAVKVNQKLSLIVYLVMGWVGIILLPIIFIRTSWIFILFIFLGGVSYTIGAWFYAQKNRPYFHMIWHIFIVIASLLHLIAILYFM
>NZ_AP019751.1|WP_000884735.1|2347372_2348560_-|UDPGP-type-1-family-protein
MLDKNQLAKYKQDHLCEYEKIMSNNEKEALEEKVASLDLDFIAKLYNDLYINKKTIDDVSAVSEVKYDIKSQMSDDEIKRLEEQGLQAIKEGQFAVLLMAGGQGTRLGYKGPKGSFEIEGVSLFELQANQLKTLNHQSGHTIQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMETPNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVKVLDPLFAGFTVEHDYDITSKTIQPKPGESVGRLVNVDCKDTVLEYSELDPEVANQFNNANIGIHAFKLGFILNAVNRELPYHLAIKNLKQLDENFGVIEQPTLKFELFYFDIFTYGTSFVTLQVPREEEFSPLKNKEGKDSVATATEDLRRMGLI

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Crispr_ID: NZ_AP019751_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019751_11

2422882-2422967

Orphan

Consensus_repeat	Method
CCAACTTGCACATTATTGTAAGCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP019751_11

>merge|NZ_AP019751|11|2422882-2422967|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTTTCGTCACCTTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTT

>NZ_AP019751|11|10|2422882-2422967|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTT	TCGTCACCTTCTATGTTGGGGCCCCG
CCAACTTGCACATTATTGTAAGCTGACTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019751.1\|WP_000600973.1\|2419544_2420309_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
NZ_AP019751.1\|WP_000184413.1\|2420903_2422115_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NZ_AP019751.1\|WP_001790034.1\|2422692_2422863_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_000602937.1\|2425491_2425977_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
NZ_AP019751.1\|WP_000808500.1\|2425031_2425478_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|223391
NZ_AP019751.1\|WP_000866971.1\|2424792_2425026_-\|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl\|CDD\|340452
NZ_AP019751.1\|WP_001566779.1\|2419301_2419553_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_000592298.1\|2414363_2417531_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NZ_AP019751.1\|WP_000076923.1\|2428328_2429333_-\|ThiF-family-adenylyltransferase	unknown	unknown	gnl\|CDD\|181084
NZ_AP019751.1\|WP_000413863.1\|2417647_2418913_-\|lipid-II:glycine-glycyltransferase-FemX	unknown	unknown	gnl\|CDD\|225224
NZ_AP019751.1\|WP_000066900.1\|2422216_2422567_-\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
NZ_AP019751.1\|WP_000643988.1\|2424186_2424786_-\|molybdenum-cofactor-guanylyltransferase-MobA	unknown	unknown	gnl\|CDD\|234725
NZ_AP019751.1\|WP_000134536.1\|2427295_2427790_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NZ_AP019751.1\|WP_000913019.1\|2429502_2430108_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226628
NZ_AP019751.1\|WP_144079005.1\|2420470_2420911_+\|winged-helix-DNA-binding-protein	unknown	unknown	gnl\|CDD\|197670
NZ_AP019751.1\|WP_001161085.1\|2413862_2414180_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_000230173.1\|2423144_2424167_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NZ_AP019751.1\|WP_000051210.1\|2413453_2413618_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_000259724.1\|2425973_2427233_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NZ_AP019751.1\|WP_000503820.1\|2427791_2428298_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	unknown	unknown	gnl\|CDD\|223595

Protein	Function_ID	Function_description	E-value
NZ_AP019751.1\|WP_000600973.1\|2419544_2420309_-\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	4.64519e-37
NZ_AP019751.1\|WP_000184413.1\|2420903_2422115_+\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.54033e-72
NZ_AP019751.1\|WP_000592298.1\|2414363_2417531_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NZ_AP019751.1\|WP_000866971.1\|2424792_2425026_-\|molybdopterin-converting-factor-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	8.16473e-25
NZ_AP019751.1\|WP_000808500.1\|2425031_2425478_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.56799e-58
NZ_AP019751.1\|WP_000076923.1\|2428328_2429333_-\|ThiF-family-adenylyltransferase	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	3.23825e-132
NZ_AP019751.1\|WP_000413863.1\|2417647_2418913_-\|lipid-II:glycine-glycyltransferase-FemX	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	3.69463e-143
NZ_AP019751.1\|WP_000066900.1\|2422216_2422567_-\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
NZ_AP019751.1\|WP_000643988.1\|2424186_2424786_-\|molybdenum-cofactor-guanylyltransferase-MobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	5.68918e-67
NZ_AP019751.1\|WP_000503820.1\|2427791_2428298_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	9.7838e-65
NZ_AP019751.1\|WP_000913019.1\|2429502_2430108_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	3.32197e-115
NZ_AP019751.1\|WP_144079005.1\|2420470_2420911_+\|winged-helix-DNA-binding-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	3.00442e-15
NZ_AP019751.1\|WP_000134536.1\|2427295_2427790_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	9.25584e-98
NZ_AP019751.1\|WP_000230173.1\|2423144_2424167_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
NZ_AP019751.1\|WP_000602937.1\|2425491_2425977_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	4.35501e-50
NZ_AP019751.1\|WP_000259724.1\|2425973_2427233_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	6.35078e-159

>NZ_AP019751.1|WP_001790034.1|2422692_2422863_+|hypothetical-protein
MFRFISFGQLVVYSTTFIPKKDILQLNGMECDINVKEPLKIYYVVILKSGIEMIFS
>NZ_AP019751.1|WP_000066900.1|2422216_2422567_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>NZ_AP019751.1|WP_000184413.1|2420903_2422115_+|MFS-transporter
MTNQGSLNKSPIFTKSFTINFFVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYPIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>NZ_AP019751.1|WP_144079005.1|2420470_2420911_+|winged-helix-DNA-binding-protein
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDLQKLQQAVVAKTNISQDQMQETINVMNQIHKILLKETHND
>NZ_AP019751.1|WP_000600973.1|2419544_2420309_-|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNNIEAVKNKLQSERVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>NZ_AP019751.1|WP_001566779.1|2419301_2419553_+|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLAIIHMGILAHSTYVYLY
>NZ_AP019751.1|WP_000413863.1|2417647_2418913_-|lipid-II:glycine-glycyltransferase-FemX
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>NZ_AP019751.1|WP_000592298.1|2414363_2417531_-|efflux-RND-transporter-permease-subunit
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTFAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASAPNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVVTIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGNIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>NZ_AP019751.1|WP_001161085.1|2413862_2414180_+|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>NZ_AP019751.1|WP_000051210.1|2413453_2413618_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDLEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>NZ_AP019751.1|WP_000230173.1|2423144_2424167_-|GTP-3',8-cyclase-MoaA
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>NZ_AP019751.1|WP_000643988.1|2424186_2424786_-|molybdenum-cofactor-guanylyltransferase-MobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>NZ_AP019751.1|WP_000866971.1|2424792_2425026_-|molybdopterin-converting-factor-subunit-1
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>NZ_AP019751.1|WP_000808500.1|2425031_2425478_-|molybdenum-cofactor-biosynthesis-protein-MoaE
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>NZ_AP019751.1|WP_000602937.1|2425491_2425977_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRNEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>NZ_AP019751.1|WP_000259724.1|2425973_2427233_-|molybdopterin-molybdotransferase-MoeA
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETTTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFVDGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>NZ_AP019751.1|WP_000134536.1|2427295_2427790_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNKTIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSNQ
>NZ_AP019751.1|WP_000503820.1|2427791_2428298_-|molybdenum-cofactor-biosynthesis-protein-MoaB
MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>NZ_AP019751.1|WP_000076923.1|2428328_2429333_-|ThiF-family-adenylyltransferase
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWDGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>NZ_AP019751.1|WP_000913019.1|2429502_2430108_-|ATP-binding-cassette-domain-containing-protein
MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

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Crispr_ID: NZ_AP019751_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019751_12

2589889-2589967

Orphan

Consensus_repeat	Method
CCAACTTGCATTGTCTCTAGAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP019751_12

>merge|NZ_AP019751|12|2589889-2589967|CRISPRCasFinder
CCAACTTGCATTGTCTCTAGAAATTGGGAATCCAATTTCTCTTAGTTGGGACTCCGCCAACTTGCATTGTCTGTAGAAA

>NZ_AP019751|12|11|2589889-2589967|CRISPRCasFinder
CCAACTTGCATTGTCTCTAGAAA	TTGGGAATCCAATTTCTCTTAGTTGGGACTCCG
CCAACTTGCATTGTCTGTAGAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019751.1\|WP_000101538.1\|2596932_2598342_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NZ_AP019751.1\|WP_001064816.1\|2587826_2589590_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_AP019751.1\|WP_000971548.1\|2581491_2582607_-\|pyridoxal-phosphate-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|223234
NZ_AP019751.1\|WP_001176871.1\|2591158_2592301_+\|glycerate-kinase	unknown	unknown	gnl\|CDD\|272872
NZ_AP019751.1\|WP_001080281.1\|2595121_2595778_+\|C39-family-peptidase	unknown	unknown	gnl\|CDD\|227323
NZ_AP019751.1\|WP_000486494.1\|2586068_2587802_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_AP019751.1\|WP_001217916.1\|2584929_2585616_-\|dethiobiotin-synthase	unknown	unknown	gnl\|CDD\|223210
NZ_AP019751.1\|WP_001046645.1\|2582584_2583592_-\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|235755
NZ_AP019751.1\|WP_001110081.1\|2583593_2584952_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|273109
NZ_AP019751.1\|WP_001185692.1\|2598479_2600558_+\|sodium:proton-antiporter	unknown	unknown	gnl\|CDD\|223104
NZ_AP019751.1\|WP_001192075.1\|2593201_2594413_+\|multidrug-effflux-MFS-transporter	unknown	unknown	gnl\|CDD\|340878
NZ_AP019751.1\|WP_000286878.1\|2580788_2581481_-\|6-carboxyhexanoate--CoA-ligase	unknown	unknown	gnl\|CDD\|224342
NZ_AP019751.1\|WP_000200943.1\|2580310_2580778_-\|QueT-transporter-family-protein	unknown	unknown	gnl\|CDD\|377623
NZ_AP019751.1\|WP_000779360.1\|2590514_2590901_-\|flippase-GtxA	unknown	unknown	gnl\|CDD\|225155
NZ_AP019751.1\|WP_000831301.1\|2592360_2593020_+\|membrane-protein	unknown	unknown	gnl\|CDD\|222878
NZ_AP019751.1\|WP_001790576.1\|2585670_2585838_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_000690199.1\|2595840_2596647_-\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|163441
NZ_AP019751.1\|WP_144079014.1\|2594535_2595009_-\|GyrI-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|226231
NZ_AP019751.1\|WP_000482647.1\|2590273_2590381_-\|type-I-toxin-antitoxin-system-Fst-family-toxin	unknown	unknown	unknown
NZ_AP019751.1\|WP_000783428.1\|2579281_2580259_+\|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B	unknown	unknown	gnl\|CDD\|273388

Protein	Function_ID	Function_description	E-value
NZ_AP019751.1\|WP_000101538.1\|2596932_2598342_+\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	0
NZ_AP019751.1\|WP_001064816.1\|2587826_2589590_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	4.21336e-146
NZ_AP019751.1\|WP_000971548.1\|2581491_2582607_-\|pyridoxal-phosphate-dependent-aminotransferase-family-protein	gnl\|CDD\|223234	COG0156, BioF, 7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism].	3.62949e-138
NZ_AP019751.1\|WP_001176871.1\|2591158_2592301_+\|glycerate-kinase	gnl\|CDD\|272872	TIGR00045, Glycerate_kinase, glycerate kinase. The only characterized member of this family so far is the glycerate kinase GlxK (EC 2.7.1.31) of E. coli. This enzyme acts after glyoxylate carboligase and 2-hydroxy-3-oxopropionate reductase (tartronate semialdehyde reductase) in the conversion of glyoxylate to 3-phosphoglycerate (the D-glycerate pathway) as a part of allantoin degradation. [Energy metabolism, Other].	0
NZ_AP019751.1\|WP_001080281.1\|2595121_2595778_+\|C39-family-peptidase	gnl\|CDD\|227323	COG4990, COG4990, Uncharacterized protein conserved in bacteria [Function unknown].	2.51069e-72
NZ_AP019751.1\|WP_000486494.1\|2586068_2587802_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	6.79158e-143
NZ_AP019751.1\|WP_001217916.1\|2584929_2585616_-\|dethiobiotin-synthase	gnl\|CDD\|223210	COG0132, BioD, Dethiobiotin synthetase [Coenzyme metabolism].	1.45777e-70
NZ_AP019751.1\|WP_001046645.1\|2582584_2583592_-\|biotin-synthase-BioB	gnl\|CDD\|235755	PRK06256, PRK06256, biotin synthase; Validated.	0
NZ_AP019751.1\|WP_001110081.1\|2583593_2584952_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl\|CDD\|273109	TIGR00508, hypothetical_protein_DESPIG_00326, adenosylmethionine-8-amino-7-oxononanoate transaminase. All members of the seed alignment have been demonstrated experimentally to act as EC 2.6.1.62, an enzyme in the biotin biosynthetic pathway. Alternate names include 7,8-diaminopelargonic acid aminotransferase, DAPA aminotransferase, and adenosylmethionine-8-amino-7-oxononanoate aminotransferase. The gene symbol is bioA in E. coli and BIO3 in S. cerevisiae. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	0
NZ_AP019751.1\|WP_001185692.1\|2598479_2600558_+\|sodium:proton-antiporter	gnl\|CDD\|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	2.07656e-103
NZ_AP019751.1\|WP_001192075.1\|2593201_2594413_+\|multidrug-effflux-MFS-transporter	gnl\|CDD\|340878	cd17320, MFS_MdfA_MDR_like, Multidrug transporter MdfA and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as MdfA (also called chloramphenicol resistance pump Cmr), EmrD, MdtM, MdtL, bicyclomycin resistance protein (also called sulfonamide resistance protein), and the uncharacterized inner membrane transport protein YdhC. EmrD is a proton-dependent secondary transporter, first identified as an efflux pump for uncouplers of oxidative phosphorylation. It expels a range of drug molecules and amphipathic compounds across the inner membrane of E. coli. Similarly, MdfA is a secondary multidrug transporter that exports a broad spectrum of structurally and electrically dissimilar toxic compounds. These MDR transporters are drug/H+ antiporters (DHA) belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.81144e-73
NZ_AP019751.1\|WP_000286878.1\|2580788_2581481_-\|6-carboxyhexanoate--CoA-ligase	gnl\|CDD\|224342	COG1424, BioW, Pimeloyl-CoA synthetase [Coenzyme metabolism].	3.89049e-130
NZ_AP019751.1\|WP_000200943.1\|2580310_2580778_-\|QueT-transporter-family-protein	gnl\|CDD\|377623	pfam06177, QueT, QueT transporter. This family includes the queT gene encoding a hypothetical integral membrane protein with 5 predicted transmembrane regions. The queT genes in Firmicutes are often preceded by the PreQ1 (7-aminomethyl-7-deazaguanine) riboswitches of two distinct classes, suggesting involvement of the QueT transporters in uptake of a queuosine biosynthetic intermediate.	0.00179995
NZ_AP019751.1\|WP_000779360.1\|2590514_2590901_-\|flippase-GtxA	gnl\|CDD\|225155	COG2246, COG2246, Predicted membrane protein [Function unknown].	1.41026e-22
NZ_AP019751.1\|WP_000831301.1\|2592360_2593020_+\|membrane-protein	gnl\|CDD\|222878	PHA02562, 46, endonuclease subunit; Provisional.	0.00700231
NZ_AP019751.1\|WP_000690199.1\|2595840_2596647_-\|metallophosphoesterase	gnl\|CDD\|163441	TIGR03729, acc_ester, putative phosphoesterase. Members of this protein family belong to the larger family pfam00149 (calcineurin-like phosphoesterase), a family largely defined by small motifs of metal-chelating residues. The subfamily in this model shows a good but imperfect co-occurrence in species with domain TIGR03715 that defines a novel class of signal peptide typical of the accessory secretory system.	1.39132e-107
NZ_AP019751.1\|WP_144079014.1\|2594535_2595009_-\|GyrI-like-domain-containing-protein	gnl\|CDD\|226231	COG3708, COG3708, Uncharacterized protein conserved in bacteria [Function unknown].	7.39658e-37
NZ_AP019751.1\|WP_000783428.1\|2579281_2580259_+\|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	5.50766e-128

>NZ_AP019751.1|WP_001064816.1|2587826_2589590_-|ABC-transporter-ATP-binding-protein
MNNQTNWIKILSGFASDSKWKIMLSILLSIISVFSGLVPYWAVFKIILMMINNAYTINSIMVYIFIALIAYISQVCCFGASTMLSHITAYEILSEIRKKLAQKLMRLPLGVVESKKIGELKNIFVDKVETIELPLAHMIPEVIGNLLLSAAIFLYIMLIDWRMASALLVTIPISIFAFKKVMSGFNETYAEQMKSNNYMNSAIVEFIEGIEVIKTFNQSQSSYKKYKDAVDNYKIHTLNWFKNTWGYMNLGASVLPSTFLGILPVGMYLISINQLNYAEFFLCIVLSLGVVAPIKNFTNYVNHLKSIQYALTEVNQILSLEELVLSTKFKKPQHYEIAFNNVGFSYNKDKDDLVFKHLSFTVPENNFTAIVGASGSGKSTIAKLISRYWDVTSGEITIGGINIKDIESKQLNDLVGFVGQDNFLLNLTFKENIKLGNPEATDEAVEKAAKLAQCHEFIEKLPDGYDTNVGTVGDKLSGGEKQRVTIARMILKDAPIIVLDEATAYVDPDNEQKIQEALNVLTQDKTLIVIAHRLSTIQHADQIIVLGKQQILEKGSHHLLLKLNGNYKKMWDTHMHTKDWGINTGHN
>NZ_AP019751.1|WP_000486494.1|2586068_2587802_-|ABC-transporter-ATP-binding-protein
MFQITFKILNWIRPYKARMILGFSMSFLNAIFIALPIFLAAKIFNNVLSHKPIYMKDILNVVIIMVLLVIGRFITAYFKSKSHESIAYEMSAKERLDIGDKLKNVRLGYFNSHHSNELTTIVTTDLTFLENFAMKMVDVVVNGYILITVLILSLLVVSWQVSLLACIGVLLSFFAIQLLERKSRQNAPAYHNVQNQLVEKVLEVIRGIQVIKSFAKENTSLKSFNQAVNESKRINTKIEMQYIPFNLLHLLSLKVVSIMIVLVACLLYMNHSIDLPTLIMISIFSFVIFDSVENINSAAHVLEMIDMTIDDIEKIKNAPELDENGKNLTIKNENIAFQNVNFSYDDKQVIKNVNFEIPTQTSTAIIGPSGSGKSTLCHLLLRFYDIDDGNIRIDGVDIKDMTLSTLMSKISAVFQKVYLFNDTIENNILFGNPGATKEEIIRAAKQACCHDFIMSLPEGYQTMLNEKGSNLSGGEKQRISIARAILKDAPIIILDEATASIDPENEQLIQTAINELSKGKTVITIAHKLETIKNADQIIVLNEGEIIQKGSHDELIRKPGMYQDFIRIKSKSAGWKL
>NZ_AP019751.1|WP_001790576.1|2585670_2585838_-|hypothetical-protein
MQLLILTDIFYRIAVYICPNSLRSLSHFNSKVKILPKFIVILRSLNSCFLEKHAP
>NZ_AP019751.1|WP_001217916.1|2584929_2585616_-|dethiobiotin-synthase
MRIFITSTNTDVGKTYVTKHLYHALKTRGHRVCIFKPFQTEERQDGTFPDLEVFKNECDLSYDITSLYTFKQPVSPHLAFKMTDQIFLNKQRVLDKVKVLDKEFDFILIEGAGGIAVPIYEGTDDFYMTKDLINDCADCVISVLPSKLGAISDAIVHQDYVNQNVSASNFLIMNRYTDSYIEKDNQITIGKLTNKTVYTFEEHATYENFSEAFLKQLIGVKNELHTTT
>NZ_AP019751.1|WP_001110081.1|2583593_2584952_-|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MNYTQQLKQKDSEYVWHPFTQMGVYSKEETIIIEKGKGSYLYDTNGNKYLDGYASLWVNVHGHNNKYLNKVIKKQLNKIAHSTLLGSSNIPSIELAEKLIEITPSNLRKVFYSDTGSASVEIAIKMAYQYWKNIDREKYAKKNKFITLNHGYHGDTIGAVSVGGIKTFHKIFKDLIFENIQVESPSFYRSNYDTENEMMTAILTNIEQILIERNDEIAGFILEPLIQGATGLFVHPKGFLKEVEKLCKKYDVLLICDEVAVGFGRTGKMFACNHEDVQPDIMCLGKAITGGYLPLAATLTSQKIYNAFLSDSHGVNTFFHGHTYTGNQIVCTVALENIRLYEKRKLLSHIETTSSTLEKQLHALKRHRNVGDVRGRGLMFGVELVTDKDSKTPLEIEKVERIVRKCKENGLMIRNLENVITFVPVLSMSNKEVKTMVRIFKKAVHNILDRKC
>NZ_AP019751.1|WP_001046645.1|2582584_2583592_-|biotin-synthase-BioB
MNLAKRILQGEQLTKETVLKIYEDTNIDTLDLLNEAYILRKHYFGKKVKLNMILNAKSGICPENCGYCGQSRDIKQKQRYALIPEEQIIDGAKVAHDNHIGTYCIVMSGRGPSDKEVDHISNTVRTIKSQHPQLKICACLGLTNDEQAKKLKSAGVDRYNHNINTSENYHDNVVTTHSYKDRTDTIELMKANNISPCSGVICGMGESNQDIVDMAFALKEMDADSIPINFLHPIKGTKFGSMDDLTPMKCLRIVALFRLINPTKEIRIAGGREVNLRSLQPLALKAANSIFVGDYLITGGQPNQLDYDMINDLGFEIDYDTCENKENKNDVSRAN
>NZ_AP019751.1|WP_000971548.1|2581491_2582607_-|pyridoxal-phosphate-dependent-aminotransferase-family-protein
MMFQEQIDLLQQKGLYRSLKSVGYIDRQYIEVENKRCTNYTSNDYLGLGQIAFDKDDFERFMRKYSYHLSSSRLISGSSTAYEEIETMLAGWLGYSACTILNSGYDANLALFNIFKNTNCVVFSDQENHASIIDGIKLSGLEKVIYKHLDIADLEKRLEKYPNQNIPKIIISDSAFSTNGDVVDIGQLVSLKHKYNATLILDVSHSFGIENYSNYQGVDILTSSLSKACGAYGGVILSSNDVKDMLINHGRPLIYSSSLPIYNLYFIKRNIEKLINADDRRTKLNSLSKYFNQKLKALNVNYNSSNSPIKFIEFDDIEAAENIHQTLLKHHVFTSYLRYPTVTKPMLRISLSYFHTEQDIDRLFEILHQED
>NZ_AP019751.1|WP_000286878.1|2580788_2581481_-|6-carboxyhexanoate--CoA-ligase
MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPIQQIKALQIIEDDKANLQHLTQECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSFGQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPYVKGELCVSDDLTYTTGYFASAKIGYHRLFDIKPVNTRYGGRIIFVDDRIDLNHYISFLESTPKQVVYERV
>NZ_AP019751.1|WP_000200943.1|2580310_2580778_-|QueT-transporter-family-protein
MTSKDITQISVIAAILTILAALKIPSIIPGLDFQLSAPAALLILAFFGIKKYFLGGLLSSLLLLVFGVFNPINVIISIIFRVIAIAVVYLLKINVLSLVLASVLGSLVSRLLLSIILNLPVWVVLLNAIPGVIFTLIVAIPLYLTLRKRMAVLLR
>NZ_AP019751.1|WP_000783428.1|2579281_2580259_+|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B
MKMNKLVKSSVATSMALLLLSGTANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKATGNINSGFVKPNPNDYDFSKLYWGAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTLGYTFGGDISISNGLSGGLNGNTAFSETINYKQESYRTTLSRNTNYKNVGWGVEAHKIMNNGWGPYGRDSFHPTYGNELFLAGRQSSAYAGQNFIAQHQMPLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMDLYQIRWNGFYWAGANYKNFKTRTFKSTYEIDWENHKVKLLDTKETENNK
>NZ_AP019751.1|WP_000482647.1|2590273_2590381_-|type-I-toxin-antitoxin-system-Fst-family-toxin
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK
>NZ_AP019751.1|WP_000779360.1|2590514_2590901_-|flippase-GtxA
MKLTQTHAEILKFIIVGGINTLNYYVVYLLLLKLLHIEYMISHITGFLVAFVISYYLNCYFVYRVKPTWRKFISFPITQIVNVSLQTVLLYVFVSWLNLPAEIAPFAGLVITIPITFVLSKWILKDSN
>NZ_AP019751.1|WP_001176871.1|2591158_2592301_+|glycerate-kinase
MQLQKIVIAPDSFKESMTAQQVGNIIKQAFTNVYGNTLHYDIIPMADGGEGTTDALMHATGATKYTVIVNDPLMRPIEACYARADEQQIAIIEMAAASGLDLLEKEERNPLYTSSYGTGELIKDALNHGAKTIILGIGGSATNDGGTGMLSALGVQFTDVNGDLLQMNGANLAHIAQIDITNLDSRLKEVTFKVACDVSNPLLGENGATYIYGPQKGADAKMIPKLDFAMSHYHDKIKMCTGKSVNQIPGSGAAGGMGAALLAFCETTLTKGIDVVFDITDFHQRIKDADLVITGEGRMDYQTIFGKTPVGVALAAKQYHIPVIAICGSLGENYQHVYDFGIDSAYSIISSPSTLEDVLQNSEQNLLNTATDIARILKLQ
>NZ_AP019751.1|WP_000831301.1|2592360_2593020_+|membrane-protein
MKRTDKYRDSYQYDNQNQNHRRQSEDASYRQQYAKGDPEEHPERYYNGRDYRREQILEEENEKSRRSKKWLYIIIAILLIIVAIFVTRALLNNDSDKVSNDPKVSQNYKKQVENQDGQINQQVDNAKENIKNNQKTDDIIKNLQNQIDNLKQQEQNKADSKLTQFYQDQINKLTEANNALKNNASQGKIESMLNDINTKFDSIKSKLESLFKDENGGAN
>NZ_AP019751.1|WP_001192075.1|2593201_2594413_+|multidrug-effflux-MFS-transporter
MQSTKTKTKHFSFLLLITLGVMTAFGPLTIDMYVPSLPKVQGDFGSTTSEIQLTLSFTMIGLALGQFIFGPLSDAFGRKRIAVSILIIFILVSGLSMFVDQLPLFLTLRFIQGLTGGGVIVIAKASAGDKFSGNALAKFLASLMVVNGIITILAPLAGGLALSVATWRSIFTILTIVALIILIGVASQLPKTSKDELKQVNFSSVIKDFGSLLKKPAFIIPMLLQGLTYVMLFSYSSASPFITQKLYNMTPQQFSIMFAVNGVGLIIVSQVVALLVEKLHRHILLIILTIIQVVGVALIILTLTFHLPLWVLLIAFFLNVCPVTSIGPLGFTMAMEERTGGSGNASSLLGLFQFILGGAVAPLVGLKGEFNTSPYMIIIFITAILLVSLQIIYFKMIKKQHVA
>NZ_AP019751.1|WP_144079014.1|2594535_2595009_-|GyrI-like-domain-containing-protein
MEYQLQQLASLTLVGIKETYENGRQAQQHIAGFWQRCYQEGVIADLQLKNNGDLAEILGLCISELDGKMSYMIAVTGDNSADIEKYDVITLASSKYMVFEAQGAVPKAVQQKMEEVHHYIHQYQADTVKSAPFFELYQDGDTTSEKYITEIWMPVKG
>NZ_AP019751.1|WP_001080281.1|2595121_2595778_+|C39-family-peptidase
MNRKILPVKPISQLFPIPMVMGCEGVSAAMMLQYNNQHIPATEIMRHWPTHPNNPHKGYVGHHLFIKLGNYHQTIFPEAYVPFLQKYNPNIVDGTGKSLEDLKGIIDQGQPVLIYHTNLGSKPLLRVFRFDNKPAKQVSNIHVTLLIGYDDYYYYYIDPLWSHIRRGLVLPAIIPNRKQIIKIRKEKMEYSFNSPGRKCIYVQPHSYTIENQQQNKHT
>NZ_AP019751.1|WP_000690199.1|2595840_2596647_-|metallophosphoesterase
MKIGTIADLHIDRHNKKTSEDYLEALVEIVKYKKLDILLIAGDISNHYQLTHQFITQLTKQLDIPVKFVPGNHDLWEVESMTTQDIWNNYKSMSQCLVGKPFIVNEEWAIIGHTGWYDYSFAAQRFSLEHLQKGKHYGATWQDKERISWGISDQNLSKIAAEQVKKDILEVGNRRVILVTHVVTHPDFIVPMPHRIFDFYNAFIGTSDFNPLYAMFDIPYSIMGHVHFRKSVIDDGRCYLCPCLGYPRQWRSEDIYQEINETIQIIEI
>NZ_AP019751.1|WP_000101538.1|2596932_2598342_+|amino-acid-permease
MARKLHRELNNRHIQLIAIGGAIGTGLFLGSGQTISLTGPSLLFTYMIIGVVLFAFMRALGELLLSNTRFNSFVDIANEYLGPFGGFVIGWTYWLCWIVSSMSDLTAMGQYFAFWYPQVPNWITVLFIVLILISFNLLGARLFGELEFWFSIIKVVTIIAMVIVGLVLIFFSFKTHYGHASFTNLISHGGMFPGGTFGFLMSFQIAVYSFIGIELIGVTAGETKDPEKTLPKAINNVPIRILLFYIGGLLVIMSVIPWNDIDPNSSPFVKLFTLIGVPFAAGVVNFVVLTAAASATNSGIYSNSRILFGLSQQGLGPKVLNKTNSHGVPYLSMLVSSIALLIAALLNYIFPNAIQLFIYVTTLSTVLFLVVWAMIIVAYLMYLKKHPEAHKNSKFKLIGGKPIAYIILAFFFFVFILLFFSDETRAAIYISPFWFIFLFFFYKKYKTNAEKLAYEQRQNDSGHFRYDNQ
>NZ_AP019751.1|WP_001185692.1|2598479_2600558_+|sodium:proton-antiporter
MALLEAFLIFIFAVIISSVINNRFPQIPTAFIQIALGVVIFIIPIQVDFQFNSEVFMFAVIAPLLFVEGTHVSRTKLLEYRKPILLMSMALVFATVVGVGYFIHWIWPALPMPAAFAIAAILCPTDAVAVSAITRGKLLPKGSMTILEGESLLNDAAGIISFKIAVTALVTGTFSLFQAVEQFIISTILGVLIGAIIGFVVVRIRIDLTANKGLKDNNTLTFIQLLTPFVVYFLAEEVHASGIIAVVIAGLIHGLERDRLIRAQTELQMNYHQIWNTFSYALNGFVFVVLGFMIPTVVIDIFQTEPDNFSFLIVITILIAIAIYACRFVWVYFWYKDFYFPKNIQSYLDEEHDSHETPPSRVRYAFIMTMCGIHGTISLSMALTLPFIITKGQAFEYRNDLLFIASFMVLISLILAQIVLPLITPSAEDTTFKGMTYQSAKIFIVQKVIQHFKNESKKDKNDTNYRPVLNQYYGELLFLLNSEPDNQNTKELKRLEDIAKVIETSTLERLIDKGKATYQDINNYRNIVELTETHRTASFVEKFANFFKMLWLRLKAMKHYKALNKESKKQEFENSFKDVQKIMRIVNHNIILRLKEEQNSTNVLEVSLVINHYYDMSRSLKWRAQRRKERQENSNQIIPQAMFHNHKLEALYLQRHLLDELIRKNKINNIVAAQIRENINYNEIVLSLQSKH

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Crispr_ID: NZ_AP019751_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP019751_13

2729183-2729290

Orphan

Consensus_repeat	Method
ATTATTATAAATAATAAGTACACTACGGTTTACAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP019751_13

>merge|NZ_AP019751|13|2729183-2729290|CRISPRCasFinder
ATTATTATAAATAATAAGTACACTACGGTTTACAGTTGGATCTTCGCTCCAACTGCATAAGAGCCACTAATTATTATAAATAATAAGTACACTACGGTTTACAGTTGG

>NZ_AP019751|13|12|2729183-2729290|CRISPRCasFinder
ATTATTATAAATAATAAGTACACTACGGTTTACAGTTGG	ATCTTCGCTCCAACTGCATAAGAGCCACTA
ATTATTATAAATAATAAGTACACTACGGTTTACAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP019751.1\|WP_000161366.1\|2729658_2730657_-\|D-lactate-dehydrogenase	unknown	unknown	gnl\|CDD\|181499
NZ_AP019751.1\|WP_000379821.1\|2739094_2740906_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|224748
NZ_AP019751.1\|WP_000178307.1\|2733784_2734648_-\|phytoene/squalene-synthase-family-protein	unknown	unknown	gnl\|CDD\|224478
NZ_AP019751.1\|WP_000160455.1\|2735817_2737311_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224154
NZ_AP019751.1\|WP_000665232.1\|2722699_2723248_+\|fatty-acid-efflux-pump-transcriptional-regulator-FarR	unknown	unknown	gnl\|CDD\|224228
NZ_AP019751.1\|WP_000725225.1\|2737966_2738734_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_AP019751.1\|WP_001221402.1\|2726174_2726366_+\|cell-wall-inhibition-responsive-protein-CwrA	unknown	unknown	unknown
NZ_AP019751.1\|WP_001051422.1\|2720065_2722555_-\|fatty-acid-efflux-MMPL-transporter-FarE	unknown	unknown	gnl\|CDD\|225272
NZ_AP019751.1\|WP_001796738.1\|2723323_2723491_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP019751.1\|WP_000871731.1\|2734684_2735812_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|132997
NZ_AP019751.1\|WP_000432897.1\|2717616_2719611_-\|ferrous-iron-transport-protein-B	unknown	unknown	gnl\|CDD\|223447
NZ_AP019751.1\|WP_000686167.1\|2732264_2733773_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224154
NZ_AP019751.1\|WP_000024129.1\|2726605_2729014_+\|copper-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319783
NZ_AP019751.1\|WP_000076661.1\|2729362_2729569_+\|copper-chaperone-CopZ	unknown	unknown	gnl\|CDD\|225328
NZ_AP019751.1\|WP_000996736.1\|2741416_2741905_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
NZ_AP019751.1\|WP_000111118.1\|2717433_2717604_-\|FeoB-associated-Cys-rich-membrane-protein	unknown	unknown	gnl\|CDD\|378908
NZ_AP019751.1\|WP_000259692.1\|2723602_2725147_-\|L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|179543
NZ_AP019751.1\|WP_000932073.1\|2719622_2719850_-\|ferrous-iron-transport-protein-A	unknown	unknown	gnl\|CDD\|224830
NZ_AP019751.1\|WP_000136500.1\|2725336_2725936_-\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
NZ_AP019751.1\|WP_001795496.1\|2737303_2737792_-\|glycosyl-4,4'-diaponeurosporenoate-acyltransferase	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_AP019751.1\|WP_000136500.1\|2725336_2725936_-\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	5.94515e-91
NZ_AP019751.1\|WP_000178307.1\|2733784_2734648_-\|phytoene/squalene-synthase-family-protein	gnl\|CDD\|224478	COG1562, ERG9, Phytoene/squalene synthetase [Lipid metabolism].	2.37403e-100
NZ_AP019751.1\|WP_000160455.1\|2735817_2737311_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	9.69418e-133
NZ_AP019751.1\|WP_000665232.1\|2722699_2723248_+\|fatty-acid-efflux-pump-transcriptional-regulator-FarR	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	8.81924e-09
NZ_AP019751.1\|WP_000725225.1\|2737966_2738734_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.53845e-31
NZ_AP019751.1\|WP_000161366.1\|2729658_2730657_-\|D-lactate-dehydrogenase	gnl\|CDD\|181499	PRK08605, PRK08605, D-lactate dehydrogenase; Validated.	0
NZ_AP019751.1\|WP_001051422.1\|2720065_2722555_-\|fatty-acid-efflux-MMPL-transporter-FarE	gnl\|CDD\|225272	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only].	1.58078e-171
NZ_AP019751.1\|WP_000379821.1\|2739094_2740906_-\|acetyltransferase	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	6.58134e-84
NZ_AP019751.1\|WP_000871731.1\|2734684_2735812_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	9.85714e-23
NZ_AP019751.1\|WP_000432897.1\|2717616_2719611_-\|ferrous-iron-transport-protein-B	gnl\|CDD\|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	0
NZ_AP019751.1\|WP_000024129.1\|2726605_2729014_+\|copper-translocating-P-type-ATPase	gnl\|CDD\|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_AP019751.1\|WP_000076661.1\|2729362_2729569_+\|copper-chaperone-CopZ	gnl\|CDD\|225328	COG2608, CopZ, Copper chaperone [Inorganic ion transport and metabolism].	3.85103e-21
NZ_AP019751.1\|WP_000996736.1\|2741416_2741905_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.6785e-11
NZ_AP019751.1\|WP_000111118.1\|2717433_2717604_-\|FeoB-associated-Cys-rich-membrane-protein	gnl\|CDD\|378908	pfam12669, P12, Virus attachment protein p12 family. This family of proteins are related to Virus attachment protein p12 from the African swine fever virus. The family appears to contain an N-terminal signal peptide followed by a short cysteine rich region. The cysteine rich region is extremely variable and it is possible that only the N-terminal region is homologous.	0.00119197
NZ_AP019751.1\|WP_000259692.1\|2723602_2725147_-\|L-glutamate-gamma-semialdehyde-dehydrogenase	gnl\|CDD\|179543	PRK03137, PRK03137, 1-pyrroline-5-carboxylate dehydrogenase; Provisional.	0
NZ_AP019751.1\|WP_000932073.1\|2719622_2719850_-\|ferrous-iron-transport-protein-A	gnl\|CDD\|224830	COG1918, FeoA, Fe2+ transport system protein A [Inorganic ion transport and metabolism].	9.02667e-20
NZ_AP019751.1\|WP_000686167.1\|2732264_2733773_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	1.03717e-133

>NZ_AP019751.1|WP_000024129.1|2726605_2729014_+|copper-translocating-P-type-ATPase
MANTKKTTLDITGMTCAACSNRIEKKLNKLDDVNAQVNLTTEKATVEYNPDQHDVQEFINTIQHLGYGVAVETVELDITGMTCAACSSRIEKVLNKMDGVQNATVNLTTEQAKVDYYPEETDADKLVTRIQKLGYDASIKDNNKDQTSRKAEALQHKLIKLIISAVLSLPLLMLMFVHLFNMHIPALFTNPWFQFILATPVQFIIGWQFYVGAYKNLRNGGANMDVLVAVGTSAAYFYSIYEMVRWLNGSTTQPHLYFETSAVLITLILFGKYLEARAKSQTTNALGELLSLQAKEARILKDGNEVMIPLNEVHVGDTLIVKPGEKIPVDGKIIKGMTAIDESMLTGESIPVEKNVDDTVIGSTMNKNGTITMTATKVGGDTALANIIKVVEEAQSSKAPIQRLADIISGYFVPIVVGIALLTFIVWITLVTPGTFEPALVASISVLVIACPCALGLATPTSIMVGTGRAAENGILFKGGEFVERTHQIDTIVLDKTGTITNGRPVVTDYHGDNQTLQLLATAEKDSEHPLAEAIVNYAKEKQLTLTETTTFKAVPGHGIEATIDHHHILVGNRKLMADNDISLPKHISDDLTYYERDGKTAMLIAVNYSLTGIIAVADTVKDHAKDAIKQLHDMGIEVAMLTGDNKNTAQAIAKQVGIDTVIADILPEEKAAQIAKLQQQGKKVAMVGDGVNDAPALVKADIGIAIGTGTEVAIEAADITILGGDLMLIPKAIYASKATIRNIRQNLFWAFGYNIAGIPIAALGLLAPWVAGAAMALSSVSVVTNALRLKKMRLEPRRKDA
>NZ_AP019751.1|WP_001221402.1|2726174_2726366_+|cell-wall-inhibition-responsive-protein-CwrA
MRILITGTVAILIILGLVKTIQDHEMTNDTSRQLSDNKDDDKVIHLNNFKNLHAKEFNPSDFF
>NZ_AP019751.1|WP_000136500.1|2725336_2725936_-|sugar-O-acetyltransferase
MTEKEKMLAEKWYDANFDQYLINERARAKDICFELNHTRPSATNKRKELIDQLFQTTTDNVSISIPFDTDYGWNVKLGKNVYVNTNCYFMDGGQITIGDNVFIGPNCGFYTATHPLNFHHRNEGFEKAGPIHIGSNTWFGGHVAVLPGVTIGEGSVIGAGSVVTKDIPPHSLAVGNPCKVVRKIDNDLPSETLNDETIK
>NZ_AP019751.1|WP_000259692.1|2723602_2725147_-|L-glutamate-gamma-semialdehyde-dehydrogenase
MVVEFKNEPGYDFSVQENVDMFKKALKDVEKELGQDIPLVINGEKIFKDDKIKSINPADTSQVIANASKATKQDVEDAFKAANEAYKSWKTWSANDRAELMLRVSAIIRRRKAEIAAIMVYEAGKPWDEAVGDAAEGIDFIEYYARSMMDLAQGKPVLDREGEHNKYFYKSIGTGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTPYIAYKLMEILEEAGLPKGVVNFVPGDPKEIGDYLVDHKDTHFVTFTGSRATGTRIYERSAVVQEGQNFLKRVIAEMGGKDAIVVDENIDTDMAAEAIVTSAFGFSGQKCSACSRAIVHKDVYDEVLEKSIKLTKELTLGNTVDNTYMGPVINKKQFDKIKNYIEIGKEEGKLEQGGGTDDSKGYFVEPTIISGLKSKDRIMQEEIFGPVVGFVKVNDFDEAIEVANDTDYGLTGAVITNNREHWIKAVNEFDVGNLYLNRGCTSAVVGYHPFGGFKMSGTDAKTGSPDYLLHFLEQKVVSEMF
>NZ_AP019751.1|WP_001796738.1|2723323_2723491_-|hypothetical-protein
MRYVISIIMGIVLAIWSFKQLSQSHLDSGFIFFFIVYVLCISYFNSDKHDKNKKR
>NZ_AP019751.1|WP_000665232.1|2722699_2723248_+|fatty-acid-efflux-pump-transcriptional-regulator-FarR
MKETDLRVIKTKKALSSSLLQLLEQQLFQTITVNQICDNALVHRTTFYKHFYDKYDLLEYLFNQLTKDYFARDISDRLNHPFQTISDTINNKEDLRDIAEFQEEDAEFNKVLKNVCIKIMHNDIKNNRDRIDIDSDIPDNLIFYIYDSLIEGFMHWIKDEKIDWPGEEIDKIFHKVINIKIK
>NZ_AP019751.1|WP_001051422.1|2720065_2722555_-|fatty-acid-efflux-MMPL-transporter-FarE
MAKFLYKMGTFIAKHKWSAVIAWIVIVAAILIPLATNAPKFDNDIKMTGLESLDTNKKIEKHFNQDSEKAQIRVVFKTTKDDGIVQPNITKDIKKTLDDIKKDDKHIDKISDPYENKQISKDKTTAFADITYDVSQTSLKDGSRDNVKSHLKDLRDNHNVQTELTGTGMTSTEVGGNSELVGIIVAFVVLLITFGSVIAAGLPIISALIGLASGVGIISLLTYAFDIPNVTLTLAVMIGLAVGIDYALFILFRYRQVMKTETDYIKGIGLAIGTAGSAVIFAGVTVVIAVCGLSLVGIDFLAVMGFASAISVIFAVFSALTLLPALISIFHKRIKVNKLQSNFKKDIDTPWSKFITGNALAAVLLGLIILVAAAIPVSHMRLGIPDDGVKPADSTQKKAYDIISDKFGEGFNGQIPMLINVKDKKDDPQGLQQDLQSVYKDIKDKKNVDIVTPPQMSKDNDYALMVVIPKKGPNAESTNDLVHDLRDYHKDAQDKYGFKTEISGQSVINIDMSKKLNEAIPLFATVIVVLAFFLLMIVFRSILIPLKAVLGFVLSLMATLGFTTLVMQDGFMKGLFGIETTGPMLAFLPVITIGILFGLAMDYEVFLMSRIHEEYSKTGDNDYSIKVGLKESGPVIVAAALIMFSVFFAFVFQEDVMIKSMGMALAFGVLFDAFVVRMMLIPALTKLFGKGSWYLPAWLNRIIPRVDIEGHALEKYKTVESQESEAKDSKETYDTTFKIYPQGATNVSKHQDVHGQDDVRSIVLDDKTMALYQEVKQQSASSFFLYDALIDYQNKHQLNSKQQVTNIEQLNKNIEKLNQLLEKNLRNKS
>NZ_AP019751.1|WP_000932073.1|2719622_2719850_-|ferrous-iron-transport-protein-A
MLNIKNGEMNKAYKIKRMDIANENMLYRLSAFGLTDDAIITIKQKCLFKGPCIIEVNGQQLSIRHCDACSIALEE
>NZ_AP019751.1|WP_000432897.1|2717616_2719611_-|ferrous-iron-transport-protein-B
MENYCILGNPNVGKTSLFNALTGSYEYIGNWSGVTVEKKVGKLKENVGQLIDLPGTYDLSPISKDETVVTDYLLNDSFSGIINIVDASQLKRNMQLTVQLLELNQPIYIGLNMIDVATKRGIKIDYHKLMKKLKTPIFPVVARTGKGTKHLLGEIKHLGEGYQPHFKINYGEKIEETIKNMCQIIMTETSHDKYQARFIAIQFLLNNMQIANELNSEVVNKLSSLRDQVDKQVEAVSVRREMERIRNHYIETLLQDVVTYPDEDKQYFSSRIDKILTHKYIGMPIFLAIMWLIFQTTFTWIGTPLSDQLDAFIGGTFTDSVKTIMNYLGVIPFLQDLITDGIIAGVGSVLVFVPQIVVLFFFISLLEDSGYMARIAVLMDRIMESFGLSGKSFIPMIIGFGCNVPSIMAARSIENEKERLTTILIAPFMSCSARLPVYALFVGIFFKENQSLVVLSLYVLGIIMAFLVSTVLTKTILKNDNAIFIVELPTYRVPSIKTLWRSTWEKAKGFVRKAGTFIFGGSVVIWLLSYVGPHGINVNINQSFLHMVGSFFGMLVQPLGFGTWQAGATLVPGFLAKEVIVSSMAIIYSSGDAGLVNVIQNQFTPLSAYAFMIFILLYIPCVSTVAAIRKETYSWKWTALAVVYPLVTAYVLTFIFYQIGHLFV
>NZ_AP019751.1|WP_000111118.1|2717433_2717604_-|FeoB-associated-Cys-rich-membrane-protein
MSVIINILIFLAIFGYALYTLVKFFKRSKQGKCGTCDINRDCCGTEQHTANHFPGK
>NZ_AP019751.1|WP_000076661.1|2729362_2729569_+|copper-chaperone-CopZ
MSQEILNVEGMSCGHCKSAVESALNNIDGVTSADVNLENGQVSVQYDDSKVAVSQMKDAIEDQGYDVV
>NZ_AP019751.1|WP_000161366.1|2729658_2730657_-|D-lactate-dehydrogenase
MTKIKIMSVRDEDMPYIKAWAEKHHVEVDITKEALTDDNVEGVAGYDGLSLSQQIPLSEHVYKRLNELGIKQIAQRSAGFDTYDLELANKYNLIVSNVPSYSPNSIAEFAVNQAINVVRHFNQIQTKVREHDFRWEPTILSKSIKDLKVAVIGTGRIGRVVADIFANGYQSDVVAYDPFPNAKIATYVDYKDTIEEAVEGADIVTLHVPATKYNHYLFNAELFKHFKKGAVFVNCARGSLVDTKALLDALDNGVIKGAALDTYEFERKLFPSDQRGKTLNDPLLESLIDREDVILTPHIAFYTEAAVKNLIVDALDATLDVLQTGDTRLRVN
>NZ_AP019751.1|WP_000686167.1|2732264_2733773_-|NAD(P)/FAD-dependent-oxidoreductase
MKIAVIGAGVTGLAAAARIASQGHEVTIFEKNNNVGGRMNQLKKDGFTFDMGPTIVMMPDVYKDVFTACGKNYEDYIELRQLRYIYDVYFDHDDRITVPTDLAELQQMLESIEPGSTHGFMSFLTDVYKKYEIARRYFLERTYRKPSDFYNMTSLVQGAKLKTLNHADQLIEHYIDNEKIQKLLAFQTLYIGIDPKRGPSLYSIIPMIEMMFGVHFIKGGMYGMAQGLAQLNKDLGVNIELNAEIEQIIIDPKFKRADAIKVNGDIRKFDKILCTADFPSVAESLMPDFAPIKKYPPHKIADLDYSCSAFLMYIGIDIDVTDQVRLHNVIFSDDFRGNIEEIFEGRLSYDPSIYVYVPAVADKSLAPEGKTGIYVLMPTPELKTGSGIDWSDEALTQQIKEIIYRKLATIEVFEDIKSHIVSETIFTPNDFEQTYHAKFGSAFGLMPTLAQSNYYRPQNVSRDYKDLYFAGASTHPGAGVPIVLTSAKITVDEMIKDIEQGV
>NZ_AP019751.1|WP_000178307.1|2733784_2734648_-|phytoene/squalene-synthase-family-protein
MTMMDMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVCRKIDDSIDVYGDIQFLNQIKEDIQSIEKYPYEHHHFQSDRRIMMALQHVAQHKNIAFQSFYNLIDTVYKDQHFTMFETDAELFGYCYGVAGTVGEVLTPILSDHETHQTYDVARRLGESLQLINILRDVGEDFDNERIYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAIAEKDFQDVMDQIKVFSIEAQPIIELAARIYIEILDEVRQANYTLHERVFVDKRKKAKLFHEINSKYHRI
>NZ_AP019751.1|WP_000871731.1|2734684_2735812_-|glycosyltransferase-family-2-protein
MKWLSRILTVIVTMSMACGALIFNRRHQLKAKTLNFNHKALTIIIPARNEEKRIGHLLHSIIQQQVPVDVIVMNDGSTDETARVARSYGATVVDVVDDTDGKWYGKSHACYQGVTHACTNRIAFVDADVTFLRKDAVETLINQYQLQGEKGLLSVQPYHITKRFYEGFSAIFNLMTVVGMNVFSTLDDGRTNQHAFGPVTLTNKEDYYATGGHKSANRHIIEGFALGSAYTSQSLPVTVYEGFPFVAFRMYQEGFQSLQEGWTKHLSTGAGGTKPKIMTAIVLWLFGSIASILGLCLSLKYRQMSVRKMVALYLSYTTQFIYLHRRVGQFSNLLMVCHPLLFMFFTKIFIQSWKQTHRYGVVEWKGRQYSISKEQ
>NZ_AP019751.1|WP_000160455.1|2735817_2737311_-|NAD(P)/FAD-dependent-oxidoreductase
MTKHIIVIGGGLGGISAAIRMAQSGYSVSLYEQNNHIGGKVNRHESDGFGFDLGPSILTMPYIFEKLFEYSKKQMSDYVTIKRLPHQWRSFFPDGTTIDLYEGIKETGQHNAILSKQDIEELQNYLNYTRRIDRITEKGYFNYGLDTLSQIIKFHGPLNALINYDYVHTMQQAIDKRISNPYLRQMLGYFIKYVGSSSYDAPAVLSMLFHMQQEQGLWYVEGGIHHLANALEKLAREEGVTIHTGARVDNIKTYQRRVTGVRLDTGEFVKADYIISNMEVIPTYKYLIHLDTQRLNKLEREFEPASSGYVMHLGVACQYPQLAHHNFFFTENAYLNYQQVFHEKVLPDDPTIYLVNTNKTDHTQAPVGYENIKVLPHIPYIQDQPFTTEDYAKFRDKILDKLEKMGLTDLRKHIIYEDVWTPEDIEKNYRSNRGAIYGVVADKKKNKGFKFPKESQYFENLYFVGGSVNPGGGIPMVTLSGQQVADKINAREAKNRK
>NZ_AP019751.1|WP_001795496.1|2737303_2737792_-|glycosyl-4,4'-diaponeurosporenoate-acyltransferase
MKKYIKTAFFCSMYWLIVQLNIANLGTRIPDKYFRQKYIIFKSFNFEKHGKFWNKWFYVRKWKHKILDGHQLNQNIYDQRHLMTINTDEIEKMIIETKRAELIHWISILPVIIFNKGPRLVKYINIFYAMIANVPIIIVQRYNRPRLTQLLRILKRRGERHD
>NZ_AP019751.1|WP_000725225.1|2737966_2738734_-|CHAP-domain-containing-protein
MKKIVTATIATAGLATIAFAGHDAQAAEQNNNGYNSNDAQSYSYTYTIDAQGNYHYTWTGNWNPSQLTQNNTYYYNNYNTYSYNNASYNNYYNHSYQYNNYTNNSQTATNNYYTGGSGASYSTTSNNVHVTTTAAPSSNGRSISNGYASGSNLYTSGQCTYYVFDRVGGKIGSTWGNASNWANAAASSGYTVNNTPKVGAIMQTTQGYYGHVAYVEGVNSNGSVRVSEMNYGHGAGVVTSRTISANQAGSYNFIH
>NZ_AP019751.1|WP_000379821.1|2739094_2740906_-|acetyltransferase
MDTKDFKRLEKMYSPRYLPGLDGLRAFAVIGIIIYHLNAQWLSGGFLGVDTFFVISGYLITSLLISEYYRTQKIDLLEFWKRRLKRLIPAVLFLICVVLTFTLIFKPELIIQMKRDAIAAIFYVSNWWYISQNVDYFNQFAIEPLKHLWSLAIEEQFYLLFPLVITFLLHRFKPRNIIQTLFIVSLISLGLMIVIHFITGDNSRVYFGTDTRLQTLLLGCILAFIWPPFALKKDISKKIVVSLDIIGISGFAVLMTLFFIVGDQDQWIYNGGFYIISFATLFIIAIAVHPSSLFAKFLSMKPLLIIGKRSYSLYLWHYPIIVFVNSYYVQGQIPVYVYIIEILLTALMAEISYRFIETPIRKKGFKAFAFLPKKKGQFARTVLVILLLVPSIVVLSGQFDALGKQHEAEKKEKKTEFKTTKKKVVKKDKQEDKQTANSKEDIKKSSPLLIGDSVMVDIGNVFTKKIPNAQIDGKVGRQLVDATPIVKSQYKDYAKKGQKVVVELGTNGAFTKDQLNELLDSFGKADIYLVSIRVPRDYEGRINKLIYEAAEKRSNVHLVDWYKASAGHPEYFAYDGIHLEYAGSKALTDLIVKTMETHATNKK
>NZ_AP019751.1|WP_000996736.1|2741416_2741905_-|GNAT-family-N-acetyltransferase
MAINIIEYNRSYKEELIEFILSIQKNEFNIKIDRDDQPDLENIEHNYLNNGGQFWLAINNHQNIVGTIGLIRLDNNMSALKKMFVDKGYRNLKIGKKLLDKVIMTCKEQNIDGIYLGTIDKFISAQYFYSNNGFREIKRGDLPSSFPKLDVDNRFYYRNLKD

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_AP019751_1	1.1\|199218\|33\|NZ_AP019751\|CRISPRCasFinder	199218-199250	33	NZ_AP019751.1	1129224-1129256	0	1.0
NZ_AP019751_1	1.1\|199218\|33\|NZ_AP019751\|CRISPRCasFinder	199218-199250	33	NZ_AP019751.1	1552702-1552734	0	1.0
NZ_AP019751_1	1.1\|199218\|33\|NZ_AP019751\|CRISPRCasFinder	199218-199250	33	NZ_AP019751.1	2062331-2062363	0	1.0
NZ_AP019751_1	1.1\|199218\|33\|NZ_AP019751\|CRISPRCasFinder	199218-199250	33	NZ_AP019751.1	1462929-1462961	0	1.0
NZ_AP019751_2	2.2\|322557\|31\|NZ_AP019751\|CRT	322557-322587	31	NZ_AP019751.1	894958-894988	0	1.0
NZ_AP019751_2	2.2\|322557\|31\|NZ_AP019751\|CRT	322557-322587	31	NZ_AP019751.1	937009-937039	0	1.0
NZ_AP019751_2	2.2\|322557\|31\|NZ_AP019751\|CRT	322557-322587	31	NZ_AP019751.1	1103040-1103070	0	1.0
NZ_AP019751_2	2.2\|322557\|31\|NZ_AP019751\|CRT	322557-322587	31	NZ_AP019751.1	1103156-1103186	0	1.0
NZ_AP019751_2	2.2\|322557\|31\|NZ_AP019751\|CRT	322557-322587	31	NZ_AP019751.1	1552808-1552838	0	1.0
NZ_AP019751_2	2.2\|322557\|31\|NZ_AP019751\|CRT	322557-322587	31	NZ_AP019751.1	2062262-2062292	0	1.0
NZ_AP019751_2	2.2\|322557\|31\|NZ_AP019751\|CRT	322557-322587	31	NZ_AP019751.1	173856-173886	0	1.0
NZ_AP019751_2	2.2\|322557\|31\|NZ_AP019751\|CRT	322557-322587	31	NZ_AP019751.1	199172-199202	0	1.0
NZ_AP019751_2	2.2\|322557\|31\|NZ_AP019751\|CRT	322557-322587	31	NZ_AP019751.1	985740-985770	0	1.0
NZ_AP019751_2	2.2\|322557\|31\|NZ_AP019751\|CRT	322557-322587	31	NZ_AP019751.1	1462825-1462855	0	1.0
NZ_AP019751_2	2.2\|322557\|31\|NZ_AP019751\|CRT	322557-322587	31	NZ_AP019751.1	1597457-1597487	0	1.0
NZ_AP019751_2	2.2\|322557\|31\|NZ_AP019751\|CRT	322557-322587	31	NZ_AP019751.1	1597515-1597545	0	1.0
NZ_AP019751_2	2.2\|322557\|31\|NZ_AP019751\|CRT	322557-322587	31	NZ_AP019751.1	2457137-2457167	0	1.0
NZ_AP019751_2	2.3\|322612\|32\|NZ_AP019751\|CRT	322612-322643	32	NZ_AP019751.1	1248085-1248116	0	1.0
NZ_AP019751_2	2.3\|322612\|32\|NZ_AP019751\|CRT	322612-322643	32	NZ_AP019751.1	1338527-1338558	0	1.0
NZ_AP019751_3	3.1\|889461\|29\|NZ_AP019751\|CRISPRCasFinder	889461-889489	29	NZ_AP019751.1	2861690-2861718	0	1.0
NZ_AP019751_2	2.1\|322501\|32\|NZ_AP019751\|CRT	322501-322532	32	NZ_AP019751.1	1248085-1248116	1	0.969
NZ_AP019751_2	2.1\|322501\|32\|NZ_AP019751\|CRT	322501-322532	32	NZ_AP019751.1	1338527-1338558	1	0.969
NZ_AP019751_2	2.2\|322557\|31\|NZ_AP019751\|CRT	322557-322587	31	NZ_AP019751.1	307291-307321	1	0.968
NZ_AP019751_2	2.2\|322557\|31\|NZ_AP019751\|CRT	322557-322587	31	NZ_AP019751.1	1005315-1005345	1	0.968
NZ_AP019751_2	2.2\|322557\|31\|NZ_AP019751\|CRT	322557-322587	31	NZ_AP019751.1	1766558-1766588	1	0.968
NZ_AP019751_2	2.2\|322557\|31\|NZ_AP019751\|CRT	322557-322587	31	NZ_AP019751.1	2696410-2696440	1	0.968
NZ_AP019751_2	2.2\|322557\|31\|NZ_AP019751\|CRT	322557-322587	31	NZ_AP019751.1	1597573-1597603	1	0.968
NZ_AP019751_2	2.3\|322612\|32\|NZ_AP019751\|CRT	322612-322643	32	NZ_AP019751.1	1746884-1746915	1	0.969
NZ_AP019751_2	2.3\|322612\|32\|NZ_AP019751\|CRT	322612-322643	32	NZ_AP019751.1	2861583-2861614	1	0.969
NZ_AP019751_3	3.1\|889461\|29\|NZ_AP019751\|CRISPRCasFinder	889461-889489	29	NZ_AP019751.1	443729-443757	1	0.966
NZ_AP019751_3	3.1\|889461\|29\|NZ_AP019751\|CRISPRCasFinder	889461-889489	29	NZ_AP019751.1	1338479-1338507	1	0.966
NZ_AP019751_3	3.1\|889461\|29\|NZ_AP019751\|CRISPRCasFinder	889461-889489	29	NZ_AP019751.1	1597580-1597608	1	0.966
NZ_AP019751_3	3.1\|889461\|29\|NZ_AP019751\|CRISPRCasFinder	889461-889489	29	NZ_AP019751.1	1909623-1909651	1	0.966
NZ_AP019751_4	4.1\|936962\|34\|NZ_AP019751\|CRISPRCasFinder	936962-936995	34	NZ_AP019751.1	1462928-1462961	1	0.971
NZ_AP019751_4	4.1\|936962\|34\|NZ_AP019751\|CRISPRCasFinder	936962-936995	34	NZ_AP019751.1	1552702-1552735	1	0.971
NZ_AP019751_2	2.1\|322501\|32\|NZ_AP019751\|CRT	322501-322532	32	NZ_AP019751.1	1746884-1746915	2	0.938
NZ_AP019751_2	2.1\|322501\|32\|NZ_AP019751\|CRT	322501-322532	32	NZ_AP019751.1	2861583-2861614	2	0.938
NZ_AP019751_2	2.2\|322557\|31\|NZ_AP019751\|CRT	322557-322587	31	NZ_AP019751.1	894900-894930	2	0.935
NZ_AP019751_2	2.2\|322557\|31\|NZ_AP019751\|CRT	322557-322587	31	NZ_AP019751.1	1248030-1248060	2	0.935
NZ_AP019751_2	2.3\|322612\|32\|NZ_AP019751\|CRT	322612-322643	32	NZ_AP019751.1	1732355-1732386	2	0.938
NZ_AP019751_3	3.1\|889461\|29\|NZ_AP019751\|CRISPRCasFinder	889461-889489	29	NZ_AP019751.1	307286-307314	2	0.931
NZ_AP019751_3	3.1\|889461\|29\|NZ_AP019751\|CRISPRCasFinder	889461-889489	29	NZ_AP019751.1	894895-894923	2	0.931
NZ_AP019751_3	3.1\|889461\|29\|NZ_AP019751\|CRISPRCasFinder	889461-889489	29	NZ_AP019751.1	937004-937032	2	0.931
NZ_AP019751_3	3.1\|889461\|29\|NZ_AP019751\|CRISPRCasFinder	889461-889489	29	NZ_AP019751.1	1732293-1732321	2	0.931
NZ_AP019751_3	3.1\|889461\|29\|NZ_AP019751\|CRISPRCasFinder	889461-889489	29	NZ_AP019751.1	199179-199207	2	0.931
NZ_AP019751_3	3.1\|889461\|29\|NZ_AP019751\|CRISPRCasFinder	889461-889489	29	NZ_AP019751.1	985747-985775	2	0.931
NZ_AP019751_3	3.1\|889461\|29\|NZ_AP019751\|CRISPRCasFinder	889461-889489	29	NZ_AP019751.1	1248037-1248065	2	0.931
NZ_AP019751_3	3.1\|889461\|29\|NZ_AP019751\|CRISPRCasFinder	889461-889489	29	NZ_AP019751.1	1248148-1248176	2	0.931
NZ_AP019751_3	3.1\|889461\|29\|NZ_AP019751\|CRISPRCasFinder	889461-889489	29	NZ_AP019751.1	1852296-1852324	2	0.931
NZ_AP019751_11	11.1\|2422912\|26\|NZ_AP019751\|CRISPRCasFinder	2422912-2422937	26	NZ_AP019751.1	1247959-1247984	2	0.923

1. spacer 1.1|199218|33|NZ_AP019751|CRISPRCasFinder matches to position: 1129224-1129256, mismatch: 0, identity: 1.0

tgggccccaacaaagagaaattggattcccaat	CRISPR spacer
tgggccccaacaaagagaaattggattcccaat	Protospacer
*********************************

2. spacer 1.1|199218|33|NZ_AP019751|CRISPRCasFinder matches to position: 1552702-1552734, mismatch: 0, identity: 1.0

tgggccccaacaaagagaaattggattcccaat	CRISPR spacer
tgggccccaacaaagagaaattggattcccaat	Protospacer
*********************************

3. spacer 1.1|199218|33|NZ_AP019751|CRISPRCasFinder matches to position: 2062331-2062363, mismatch: 0, identity: 1.0

tgggccccaacaaagagaaattggattcccaat	CRISPR spacer
tgggccccaacaaagagaaattggattcccaat	Protospacer
*********************************

4. spacer 1.1|199218|33|NZ_AP019751|CRISPRCasFinder matches to position: 1462929-1462961, mismatch: 0, identity: 1.0

tgggccccaacaaagagaaattggattcccaat	CRISPR spacer
tgggccccaacaaagagaaattggattcccaat	Protospacer
*********************************

5. spacer 2.2|322557|31|NZ_AP019751|CRT matches to position: 894958-894988, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

6. spacer 2.2|322557|31|NZ_AP019751|CRT matches to position: 937009-937039, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

7. spacer 2.2|322557|31|NZ_AP019751|CRT matches to position: 1103040-1103070, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

8. spacer 2.2|322557|31|NZ_AP019751|CRT matches to position: 1103156-1103186, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

9. spacer 2.2|322557|31|NZ_AP019751|CRT matches to position: 1552808-1552838, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

10. spacer 2.2|322557|31|NZ_AP019751|CRT matches to position: 2062262-2062292, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

11. spacer 2.2|322557|31|NZ_AP019751|CRT matches to position: 173856-173886, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

12. spacer 2.2|322557|31|NZ_AP019751|CRT matches to position: 199172-199202, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

13. spacer 2.2|322557|31|NZ_AP019751|CRT matches to position: 985740-985770, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

14. spacer 2.2|322557|31|NZ_AP019751|CRT matches to position: 1462825-1462855, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

15. spacer 2.2|322557|31|NZ_AP019751|CRT matches to position: 1597457-1597487, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

16. spacer 2.2|322557|31|NZ_AP019751|CRT matches to position: 1597515-1597545, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

17. spacer 2.2|322557|31|NZ_AP019751|CRT matches to position: 2457137-2457167, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

18. spacer 2.3|322612|32|NZ_AP019751|CRT matches to position: 1248085-1248116, mismatch: 0, identity: 1.0

tagaagctggcggaaagtcagcttacaataat	CRISPR spacer
tagaagctggcggaaagtcagcttacaataat	Protospacer
********************************

19. spacer 2.3|322612|32|NZ_AP019751|CRT matches to position: 1338527-1338558, mismatch: 0, identity: 1.0

tagaagctggcggaaagtcagcttacaataat	CRISPR spacer
tagaagctggcggaaagtcagcttacaataat	Protospacer
********************************

20. spacer 3.1|889461|29|NZ_AP019751|CRISPRCasFinder matches to position: 2861690-2861718, mismatch: 0, identity: 1.0

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtttgtagaatttcttttcgaaa	Protospacer
*****************************

21. spacer 2.1|322501|32|NZ_AP019751|CRT matches to position: 1248085-1248116, mismatch: 1, identity: 0.969

tagaagctggcggaaagtcagcatacaataat	CRISPR spacer
tagaagctggcggaaagtcagcttacaataat	Protospacer
********************** *********

22. spacer 2.1|322501|32|NZ_AP019751|CRT matches to position: 1338527-1338558, mismatch: 1, identity: 0.969

tagaagctggcggaaagtcagcatacaataat	CRISPR spacer
tagaagctggcggaaagtcagcttacaataat	Protospacer
********************** *********

23. spacer 2.2|322557|31|NZ_AP019751|CRT matches to position: 307291-307321, mismatch: 1, identity: 0.968

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
catagaatttcgaaaagaaattctacaggca	Protospacer
** ****************************

24. spacer 2.2|322557|31|NZ_AP019751|CRT matches to position: 1005315-1005345, mismatch: 1, identity: 0.968

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttctaaaagaaattctacaggca	Protospacer
*********** *******************

25. spacer 2.2|322557|31|NZ_AP019751|CRT matches to position: 1766558-1766588, mismatch: 1, identity: 0.968

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgtaaagaaattctacaggca	Protospacer
************ ******************

26. spacer 2.2|322557|31|NZ_AP019751|CRT matches to position: 2696410-2696440, mismatch: 1, identity: 0.968

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaatgaaattctacaggca	Protospacer
*************** ***************

27. spacer 2.2|322557|31|NZ_AP019751|CRT matches to position: 1597573-1597603, mismatch: 1, identity: 0.968

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacagaca	Protospacer
****************************.**

28. spacer 2.3|322612|32|NZ_AP019751|CRT matches to position: 1746884-1746915, mismatch: 1, identity: 0.969

tagaagctggcggaaagtcagcttacaataat	CRISPR spacer
tagaagctggcggaaagtcagcttacgataat	Protospacer
**************************.*****

29. spacer 2.3|322612|32|NZ_AP019751|CRT matches to position: 2861583-2861614, mismatch: 1, identity: 0.969

tagaagctggcggaaagtcagcttacaataat	CRISPR spacer
tagaagctggcggaaagtcaggttacaataat	Protospacer
********************* **********

30. spacer 3.1|889461|29|NZ_AP019751|CRISPRCasFinder matches to position: 443729-443757, mismatch: 1, identity: 0.966

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcttgtagaatttcttttcgaaa	Protospacer
*******.*********************

31. spacer 3.1|889461|29|NZ_AP019751|CRISPRCasFinder matches to position: 1338479-1338507, mismatch: 1, identity: 0.966

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaa	Protospacer
********.********************

32. spacer 3.1|889461|29|NZ_AP019751|CRISPRCasFinder matches to position: 1597580-1597608, mismatch: 1, identity: 0.966

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaa	Protospacer
********.********************

33. spacer 3.1|889461|29|NZ_AP019751|CRISPRCasFinder matches to position: 1909623-1909651, mismatch: 1, identity: 0.966

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaa	Protospacer
********.********************

34. spacer 4.1|936962|34|NZ_AP019751|CRISPRCasFinder matches to position: 1462928-1462961, mismatch: 1, identity: 0.971

attgagaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
****.*****************************

35. spacer 4.1|936962|34|NZ_AP019751|CRISPRCasFinder matches to position: 1552702-1552735, mismatch: 1, identity: 0.971

attgagaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
****.*****************************

36. spacer 2.1|322501|32|NZ_AP019751|CRT matches to position: 1746884-1746915, mismatch: 2, identity: 0.938

tagaagctggcggaaagtcagcatacaataat	CRISPR spacer
tagaagctggcggaaagtcagcttacgataat	Protospacer
********************** ***.*****

37. spacer 2.1|322501|32|NZ_AP019751|CRT matches to position: 2861583-2861614, mismatch: 2, identity: 0.938

tagaagctggcggaaagtcagcatacaataat	CRISPR spacer
tagaagctggcggaaagtcaggttacaataat	Protospacer
*********************  *********

38. spacer 2.2|322557|31|NZ_AP019751|CRT matches to position: 894900-894930, mismatch: 2, identity: 0.935

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaatttctacagaca	Protospacer
******************* ********.**

39. spacer 2.2|322557|31|NZ_AP019751|CRT matches to position: 1248030-1248060, mismatch: 2, identity: 0.935

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcaaaaagaaattctacagaca	Protospacer
***********.****************.**

40. spacer 2.3|322612|32|NZ_AP019751|CRT matches to position: 1732355-1732386, mismatch: 2, identity: 0.938

tagaagctggcggaaagtcagcttacaataat	CRISPR spacer
tagaagctgacgaaaagtcagcttacaataat	Protospacer
*********.**.*******************

41. spacer 3.1|889461|29|NZ_AP019751|CRISPRCasFinder matches to position: 307286-307314, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

42. spacer 3.1|889461|29|NZ_AP019751|CRISPRCasFinder matches to position: 894895-894923, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaaattcttttcgaaa	Protospacer
********.******* ************

43. spacer 3.1|889461|29|NZ_AP019751|CRISPRCasFinder matches to position: 937004-937032, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

44. spacer 3.1|889461|29|NZ_AP019751|CRISPRCasFinder matches to position: 1732293-1732321, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

45. spacer 3.1|889461|29|NZ_AP019751|CRISPRCasFinder matches to position: 199179-199207, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

46. spacer 3.1|889461|29|NZ_AP019751|CRISPRCasFinder matches to position: 985747-985775, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

47. spacer 3.1|889461|29|NZ_AP019751|CRISPRCasFinder matches to position: 1248037-1248065, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaatttctttttgaaa	Protospacer
********.***************.****

48. spacer 3.1|889461|29|NZ_AP019751|CRISPRCasFinder matches to position: 1248148-1248176, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaatttctttttgaaa	Protospacer
********.***************.****

49. spacer 3.1|889461|29|NZ_AP019751|CRISPRCasFinder matches to position: 1852296-1852324, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcatggtctgtagaatttcttttcgaaa	Protospacer
***** **.********************

50. spacer 11.1|2422912|26|NZ_AP019751|CRISPRCasFinder matches to position: 1247959-1247984, mismatch: 2, identity: 0.923

tcgtcaccttctatgttggggccccg	CRISPR spacer
tcgtcagcttctgtgttggggccccg	Protospacer
****** *****.*************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_AP019751_3	3.1\|889461\|29\|NZ_AP019751\|CRISPRCasFinder	889461-889489	29	MN693281	Marine virus AFVG_25M371, complete genome	6448-6476	7	0.759
NZ_AP019751_10	10.1\|2323724\|33\|NZ_AP019751\|CRISPRCasFinder	2323724-2323756	33	JN882286	Cronobacter phage vB_CsaP_GAP52, complete genome	23035-23067	7	0.788
NZ_AP019751_10	10.1\|2323724\|33\|NZ_AP019751\|CRISPRCasFinder	2323724-2323756	33	CP030544	Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence	7568-7600	7	0.788
NZ_AP019751_2	2.1\|322501\|32\|NZ_AP019751\|CRT	322501-322532	32	NZ_CP044300	Escherichia coli strain P59A plasmid pP59A-2, complete sequence	114277-114308	8	0.75
NZ_AP019751_7	7.1\|1766612\|32\|NZ_AP019751\|CRISPRCasFinder	1766612-1766643	32	MT889383	Mycobacterium phage MiniLon, complete genome	11248-11279	9	0.719
NZ_AP019751_7	7.1\|1766612\|32\|NZ_AP019751\|CRISPRCasFinder	1766612-1766643	32	KT281791	Mycobacterium phage Lolly9, complete genome	11248-11279	9	0.719

1. spacer 3.1|889461|29|NZ_AP019751|CRISPRCasFinder matches to MN693281 (Marine virus AFVG_25M371, complete genome) position: , mismatch: 7, identity: 0.759

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtttgtaggatttcttctaagtg	Protospacer
**************.*******.* .. .

2. spacer 10.1|2323724|33|NZ_AP019751|CRISPRCasFinder matches to JN882286 (Cronobacter phage vB_CsaP_GAP52, complete genome) position: , mismatch: 7, identity: 0.788

ttgcatatctttagctttattgtttgcaactga	CRISPR spacer
ttgcatatctttagctttatagcttttatatgc	Protospacer
******************** *.** .*  **

3. spacer 10.1|2323724|33|NZ_AP019751|CRISPRCasFinder matches to CP030544 (Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.788

ttgcatatctttagctttattgtttgcaactga	CRISPR spacer
ttgaataactttagctttattgttataaacagt	Protospacer
*** *** ****************   *** *

4. spacer 2.1|322501|32|NZ_AP019751|CRT matches to NZ_CP044300 (Escherichia coli strain P59A plasmid pP59A-2, complete sequence) position: , mismatch: 8, identity: 0.75

tagaagctggcggaaagtcagcatacaataat	CRISPR spacer
aagaagctggcggaacttcagcattagttaaa	Protospacer
 **************  *******  . ***

5. spacer 7.1|1766612|32|NZ_AP019751|CRISPRCasFinder matches to MT889383 (Mycobacterium phage MiniLon, complete genome) position: , mismatch: 9, identity: 0.719

gcacattattgaaatctgacttttggtcagct	CRISPR spacer
accccttcttgaaatctgactttaggtcctga	Protospacer
.* * ** *************** ****

6. spacer 7.1|1766612|32|NZ_AP019751|CRISPRCasFinder matches to KT281791 (Mycobacterium phage Lolly9, complete genome) position: , mismatch: 9, identity: 0.719

gcacattattgaaatctgacttttggtcagct	CRISPR spacer
accccttcttgaaatctgactttaggtcctga	Protospacer
.* * ** *************** ****

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

379805 : 422455

Staphylococcus_phage(86.76%)

holin,terminase,capsid,protease,portal,tail,integrase,head

attL 379695:379712|attR 423141:423158

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
379695:379712	attL	NA	NA	NA	NA
WP_144078889.1\|379805_381011_-\|integrase	tyrosine-type recombinase/integrase	A0A1X9H094	Staphylococcus_phage	1.9e-221	99.5
WP_000391618.1\|381186_381726_-	type II toxin-antitoxin system PemK/MazF family toxin	U5U4R0	Staphylococcus_phage	9.0e-14	33.1
WP_060552628.1\|381925_382414_-	hypothetical protein	NA	NA	NA	NA
WP_031783378.1\|382470_383241_-	helix-turn-helix domain-containing protein	A0A1P8L6G7	Staphylococcus_phage	1.1e-140	99.6
WP_144078890.1\|383399_383624_+	DUF739 family protein	A7TW90	Staphylococcus_phage	3.8e-35	98.6
WP_000435341.1\|383641_383902_+	transcriptional regulator	A7TW91	Staphylococcus_phage	2.7e-40	100.0
WP_000351243.1\|383925_384465_-	hypothetical protein	A7TW92	Staphylococcus_phage	1.7e-97	100.0
WP_001148337.1\|384521_385271_+	phage antirepressor KilAC domain-containing protein	Q8SDM9	Staphylococcus_phage	4.4e-136	99.6
WP_000435360.1\|385283_385727_+	hypothetical protein	W5R971	Staphylococcus_phage	1.5e-75	100.0
WP_057520785.1\|385741_385882_+	hypothetical protein	A0A2I6PDG0	Staphylococcus_phage	5.5e-16	97.8
WP_001814660.1\|385896_386529_-	hypothetical protein	A7TW95	Staphylococcus_phage	7.6e-105	92.4
WP_001025595.1\|386584_386911_+	hypothetical protein	G4KNN2	Staphylococcus_phage	5.4e-54	100.0
WP_144078891.1\|386907_387126_+	hypothetical protein	A0A068A2A3	Staphylococcus_phage	1.9e-31	98.6
WP_001124198.1\|387155_387419_+	helix-turn-helix domain-containing protein	A0A2I6PEL8	Staphylococcus_phage	2.5e-46	100.0
WP_144078892.1\|387431_387599_+	DUF1270 family protein	S4V7J2	Staphylococcus_phage	2.0e-20	92.7
WP_144078893.1\|387599_387920_+	hypothetical protein	S4V968	Staphylococcus_phage	4.0e-54	99.1
WP_000291075.1\|388013_388274_+	DUF1108 family protein	A0A059T5A3	Staphylococcus_phage	1.2e-43	100.0
WP_000802315.1\|388281_388518_+	hypothetical protein	D2JGJ9	Staphylococcus_phage	2.7e-39	100.0
WP_000002513.1\|388510_388990_+	siphovirus Gp157 family protein	D2JGK0	Staphylococcus_phage	5.3e-82	100.0
WP_001043066.1\|388989_389628_+	ERF family protein	M9NSS5	Staphylococcus_phage	2.8e-115	99.5
WP_000934779.1\|389627_390053_+	single-stranded DNA-binding protein	R4IG44	Staphylococcus_phage	3.7e-63	87.9
WP_144078894.1\|390066_390762_+	hypothetical protein	A0A2H4JAQ0	uncultured_Caudovirales_phage	3.6e-132	98.7
WP_144078895.1\|390733_391555_+	phage replisome organizer N-terminal domain-containing protein	A0A0H3U476	Staphylococcus_phage	1.9e-119	95.7
WP_000443354.1\|391567_392353_+	ATP-binding protein	A0A059T7P1	Staphylococcus_phage	3.6e-144	99.2
WP_000628833.1\|392349_392508_+	hypothetical protein	A0A2I6PDX0	Staphylococcus_phage	3.4e-22	100.0
WP_001123695.1\|392520_392742_+	DUF3269 family protein	A0A0H3U2V4	Staphylococcus_phage	2.2e-35	100.0
WP_031860309.1\|392751_393159_+	RusA family crossover junction endodeoxyribonuclease	A9CR74	Staphylococcus_phage	1.1e-72	99.3
WP_001187254.1\|393158_393344_+	DUF3113 family protein	Q4ZA46	Staphylococcus_virus	4.1e-27	100.0
WP_144078896.1\|393344_393962_+	hypothetical protein	A0A0H3U4U9	Staphylococcus_phage	7.5e-81	97.1
WP_031867833.1\|393961_394216_+	DUF3310 domain-containing protein	A0A059T7J9	Staphylococcus_phage	3.7e-42	98.8
WP_078100129.1\|394215_394464_+	hypothetical protein	A0A0K1LL46	Staphylococcus_phage	1.2e-40	96.3
WP_144079023.1\|394477_394885_+	hypothetical protein	A0A0H4IPW3	Staphylococcus_phage	5.2e-46	74.1
WP_144078897.1\|394884_395241_+	acetyltransferase	A0A1X9H0B8	Staphylococcus_phage	2.6e-38	74.4
WP_001065101.1\|395233_395470_+	DUF1024 family protein	A0A0H3U313	Staphylococcus_phage	5.3e-35	100.0
WP_144078898.1\|395693_396227_+	dUTP pyrophosphatase	A1KX16	Staphylococcus_virus	5.1e-94	97.2
WP_144078899.1\|396263_396470_+	DUF1381 domain-containing protein	A0A1W6JPY0	Staphylococcus_phage	7.1e-20	98.5
WP_144078900.1\|396466_396670_+	hypothetical protein	B2ZYX5	Staphylococcus_phage	2.2e-29	95.5
WP_144078901.1\|396662_396812_+	transcriptional regulator	A0A1W6JPZ2	Staphylococcus_phage	3.8e-15	89.8
WP_144079024.1\|396811_397012_+	DUF1514 family protein	R9QT57	Staphylococcus_phage	3.2e-25	92.4
WP_144078902.1\|397082_397463_+	hypothetical protein	A0A2H4J3L6	uncultured_Caudovirales_phage	2.5e-10	36.6
WP_144078903.1\|397633_397819_+	type II toxin-antitoxin system HicA family toxin	A0A0D4DC32	Acinetobacter_phage	4.6e-18	73.7
WP_144078904.1\|397853_398249_+	type II toxin-antitoxin system HicB family antitoxin	M1PG28	Streptococcus_phage	3.0e-27	44.0
WP_144078905.1\|398299_398674_+	HNH endonuclease	A0A2I6PDH9	Staphylococcus_phage	2.6e-44	90.2
WP_000402904.1\|398730_399075_+	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
WP_000625088.1\|399071_400733_+\|terminase	terminase large subunit	A0A2I6PDJ8	Staphylococcus_phage	0.0e+00	100.0
WP_144078906.1\|400748_401936_+\|portal	phage portal protein	G4KNQ1	Staphylococcus_phage	1.4e-216	99.0
WP_144078907.1\|401919_402657_+\|protease	ATP-dependent Clp protease proteolytic subunit	Q8LTH1	Staphylococcus_phage	4.8e-127	98.4
WP_144078908.1\|402680_403826_+\|capsid	phage major capsid protein	A0A1W6JPL4	Staphylococcus_phage	3.0e-200	92.1
WP_144078909.1\|403848_404133_+	hypothetical protein	A0A1W6JPL8	Staphylococcus_phage	9.5e-39	84.0
WP_144078910.1\|404122_404416_+\|head,tail	phage head-tail adapter protein	A0A2I6PDJ5	Staphylococcus_phage	1.4e-37	83.0
WP_144078911.1\|404390_404753_+\|head,tail	head-tail adaptor protein	G4KNQ4	Staphylococcus_phage	1.2e-62	95.8
WP_144078912.1\|404749_405154_+	HK97 gp10 family phage protein	G4KNQ5	Staphylococcus_phage	1.9e-61	88.8
WP_144078913.1\|405150_405558_+	hypothetical protein	G4KNQ6	Staphylococcus_phage	6.9e-67	91.9
WP_144078914.1\|405558_406200_+\|tail	phage tail protein	A0EWZ9	Staphylococcus_phage	1.6e-110	93.0
WP_144078915.1\|406262_406466_+	Ig-like domain-containing protein	A0A075LYE8	Staphylococcus_phage	1.2e-16	66.7
WP_144078916.1\|406515_406866_+	hypothetical protein	G4KNQ8	Staphylococcus_phage	4.3e-49	81.9
WP_162633478.1\|406892_407054_+	hypothetical protein	A0A0H3U330	Staphylococcus_phage	4.3e-20	92.5
WP_144078917.1\|407110_411643_+\|tail	phage tail tape measure protein	W5R8I2	Staphylococcus_phage	0.0e+00	90.6
WP_144078918.1\|411639_413124_+\|tail	phage tail family protein	A0A2I6PDJ0	Staphylococcus_phage	7.4e-292	97.8
WP_144078919.1\|413139_416925_+	hypothetical protein	Q9MBN9	Staphylococcus_prophage	0.0e+00	96.4
WP_001153681.1\|416914_417067_+	hypothetical protein	D2JLG0	Staphylococcus_phage	5.2e-20	100.0
WP_001040261.1\|417113_417401_+	hypothetical protein	D2JLG1	Staphylococcus_phage	1.3e-43	100.0
WP_000539688.1\|417458_417755_+	DUF2951 domain-containing protein	D2JLG2	Staphylococcus_phage	2.9e-46	100.0
WP_072357969.1\|417904_418081_+\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	6.5e-22	96.6
WP_047551145.1\|418133_418241_-	hypothetical protein	NA	NA	NA	NA
WP_045178738.1\|418292_418547_+\|holin	phage holin	D2JLG4	Staphylococcus_phage	3.4e-40	98.8
WP_111761863.1\|418558_419314_+	CHAP domain-containing protein	Q4ZCZ2	Staphylococcus_virus	8.4e-151	98.0
WP_111761864.1\|419752_420688_+	bi-component leukocidin LukPQ subunit P	A0A2H4PQI5	Staphylococcus_phage	1.6e-162	91.5
WP_086037611.1\|420689_421670_+	bi-component leukocidin LukPQ subunit Q	Q9MBN2	Staphylococcus_prophage	1.5e-152	83.5
WP_106096712.1\|422110_422455_+	complement inhibitor SCIN family protein	A7TWS0	Staphylococcus_phage	2.5e-25	56.2
423141:423158	attR	NA	NA	NA	NA

DBSCAN-SWA_2

826550 : 834371

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000244415.1\|826550_827606_-	two-component system sensor histidine kinase SaeS	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
WP_000149344.1\|827605_828292_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037807.1\|828266_828740_-	DoxX family protein	NA	NA	NA	NA
WP_001093562.1\|829082_829523_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_000604990.1\|829802_830387_-	hypothetical protein	NA	NA	NA	NA
WP_001062972.1\|830485_831199_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000941336.1\|831202_831622_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_000446724.1\|831623_832292_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000604515.1\|832642_833236_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.2e-38	43.5
WP_001217797.1\|833219_834371_+	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	2.1e-23	36.1

DBSCAN-SWA_3

846343 : 861074

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663032.1\|846343_847402_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	1.8e-21	26.7
WP_000197271.1\|847696_848239_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000429008.1\|848919_849837_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	2.8e-07	22.4
WP_031760357.1\|849926_850028_+	hypothetical protein	NA	NA	NA	NA
WP_000193751.1\|850105_851611_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_000930014.1\|851951_852452_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_001068497.1\|852471_853338_-	DMT family transporter	NA	NA	NA	NA
WP_000692521.1\|854138_854537_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_000855505.1\|854499_856605_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000562498.1\|856722_857694_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000499195.1\|858207_858363_+	hypothetical protein	NA	NA	NA	NA
WP_000876318.1\|858401_859373_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_001245573.1\|859359_860316_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_000616840.1\|860312_861074_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	6.5e-18	31.6

DBSCAN-SWA_4

1104520 : 1112993

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000861572.1\|1104520_1105003_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7
WP_000009495.1\|1104989_1106114_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000174053.1\|1106117_1106822_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
WP_000848350.1\|1106821_1107085_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666799.1\|1107086_1107758_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_000032727.1\|1107750_1109940_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.0e-140	39.7
WP_000483713.1\|1109918_1111403_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-45	31.7
WP_000030823.1\|1111395_1112424_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.3e-61	41.4
WP_000238663.1\|1112426_1112993_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.0e-28	40.1

DBSCAN-SWA_5

1164651 : 1224784

Staphylococcus_phage(69.01%)

holin,terminase,capsid,tRNA,portal,tail,plate,head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000401377.1\|1164651_1165134_+	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	2.6e-28	46.2
WP_000843611.1\|1165195_1166335_-	nucleotidyltransferase	NA	NA	NA	NA
WP_000872158.1\|1166461_1167019_+	DUF177 domain-containing protein	NA	NA	NA	NA
WP_000290472.1\|1167098_1167272_+	50S ribosomal protein L32	NA	NA	NA	NA
WP_000861313.1\|1167388_1168774_-	recombinase family protein	I1W625	Staphylococcus_phage	2.5e-265	100.0
WP_000337827.1\|1168882_1169062_+	hypothetical protein	Q4ZBP0	Staphylococcus_phage	3.7e-25	100.0
WP_031902221.1\|1169041_1169974_-	hypothetical protein	A0EWN8	Staphylococcus_virus	6.3e-172	98.4
WP_050971912.1\|1170005_1170470_-	ImmA/IrrE family metallo-endopeptidase	A0A0H4J322	Staphylococcus_phage	5.3e-79	95.4
WP_015978337.1\|1170491_1170821_-	helix-turn-helix transcriptional regulator	A0A0H4ITV7	Staphylococcus_phage	2.4e-54	100.0
WP_033842713.1\|1170997_1171246_+	helix-turn-helix transcriptional regulator	A0A0H4IPU8	Staphylococcus_phage	1.1e-38	98.8
WP_061393900.1\|1171258_1171705_+	hypothetical protein	A0A075M4D9	Staphylococcus_phage	2.4e-76	98.0
WP_086037489.1\|1171719_1171863_+	hypothetical protein	A0A2I6PDG0	Staphylococcus_phage	2.1e-15	93.5
WP_000642492.1\|1171852_1172062_-	hypothetical protein	W5R9J5	Staphylococcus_phage	1.2e-30	100.0
WP_031807890.1\|1172118_1172895_+	phage antirepressor KilAC domain-containing protein	M1RZB2	Staphylococcus_phage	1.0e-135	94.2
WP_000390105.1\|1172911_1173106_+	hypothetical protein	E9LT75	Staphylococcus_phage	1.2e-29	100.0
WP_000395457.1\|1173309_1173540_-	hypothetical protein	R4IG40	Staphylococcus_phage	2.3e-35	100.0
WP_001619936.1\|1173719_1173881_+	DUF1270 family protein	Q4ZDA3	Staphylococcus_virus	5.0e-21	100.0
WP_000291090.1\|1173972_1174233_+	DUF1108 family protein	Q4ZDA1	Staphylococcus_virus	1.2e-43	100.0
WP_001077280.1\|1174242_1174464_+	DUF2483 family protein	A0A0E3TAJ7	Staphylococcus_phage	2.4e-34	100.0
WP_144078948.1\|1174456_1175236_+	AAA family ATPase	Q9G028	Staphylococcus_virus	2.1e-141	99.6
WP_000704713.1\|1175265_1175820_+	single-stranded DNA-binding protein	A7TWM8	Staphylococcus_phage	1.0e-100	100.0
WP_001619937.1\|1175832_1176498_+	hypothetical protein	Q8SDW3	Staphylococcus_phage	1.1e-125	100.0
WP_000240901.1\|1176497_1177277_+	AP2 domain-containing protein	A0A2H4J5K3	uncultured_Caudovirales_phage	7.3e-49	46.1
WP_000504989.1\|1177248_1178052_+	phage replisome organizer N-terminal domain-containing protein	A0A2H4JCF5	uncultured_Caudovirales_phage	2.5e-121	99.6
WP_001564581.1\|1178061_1178835_+	ATP-binding protein	A0A2H4PQI3	Staphylococcus_phage	1.5e-142	98.8
WP_000256592.1\|1178828_1178987_+	hypothetical protein	A1KX06	Staphylococcus_virus	9.9e-22	98.1
WP_001123673.1\|1178999_1179221_+	DUF3269 family protein	A7TWN4	Staphylococcus_phage	1.3e-35	100.0
WP_000401956.1\|1179230_1179638_+	RusA family crossover junction endodeoxyribonuclease	A9CR74	Staphylococcus_phage	3.2e-72	97.8
WP_001187255.1\|1179637_1179823_+	DUF3113 family protein	Q4ZA46	Staphylococcus_virus	1.3e-25	95.1
WP_001140287.1\|1179823_1180195_+	hypothetical protein	Q4ZAY2	Staphylococcus_virus	8.5e-56	98.4
WP_144078949.1\|1180195_1180444_+	hypothetical protein	Q4ZAY1	Staphylococcus_virus	8.8e-41	98.8
WP_001065066.1\|1180457_1180700_+	DUF1024 family protein	E9LT37	Staphylococcus_phage	4.4e-37	100.0
WP_000097971.1\|1180699_1180906_+	Lar family restriction alleviation protein	A0A1W6JNF7	Staphylococcus_phage	1.6e-24	81.2
WP_144078950.1\|1180898_1181429_+	dUTP diphosphatase	I1W653	Staphylococcus_phage	9.6e-93	97.2
WP_001652276.1\|1181465_1181711_+	hypothetical protein	Q9B0F1	Staphylococcus_virus	2.9e-28	93.8
WP_001652277.1\|1181707_1181914_+	DUF1381 domain-containing protein	A0A2I6PDB6	Staphylococcus_phage	1.9e-25	86.8
WP_000141185.1\|1181910_1182105_+	hypothetical protein	S4SX95	Staphylococcus_phage	2.3e-28	98.4
WP_001072795.1\|1182101_1182305_+	hypothetical protein	A0A0N9BAX5	Staphylococcus_phage	5.2e-31	100.0
WP_000608274.1\|1182297_1182534_+	hypothetical protein	A0A2I6PDD1	Staphylococcus_phage	1.3e-36	100.0
WP_001555739.1\|1182523_1182910_+	hypothetical protein	A0A2I6PDC1	Staphylococcus_phage	3.0e-64	100.0
WP_000595244.1\|1182909_1183083_+	transcriptional activator RinB	S4SVE4	Staphylococcus_phage	6.4e-22	100.0
WP_000990005.1\|1183083_1183230_+	hypothetical protein	B2ZYX7	Staphylococcus_phage	2.2e-15	100.0
WP_000162696.1\|1183253_1183676_+	RinA family phage transcriptional activator	S4V7K2	Staphylococcus_phage	1.6e-74	100.0
WP_001038245.1\|1183862_1184357_+\|terminase	terminase small subunit	A0A0F6N3K6	Staphylococcus_phage	2.3e-88	99.4
WP_144078951.1\|1184359_1185655_+\|terminase	PBSX family phage terminase large subunit	A0A0F6N3L3	Staphylococcus_phage	8.2e-255	99.1
WP_031790414.1\|1185665_1187201_+\|portal	phage portal protein	A1KX25	Staphylococcus_virus	2.6e-284	97.8
WP_144078952.1\|1187207_1188203_+\|capsid	minor capsid protein	E0Y3K7	Staphylococcus_virus	4.2e-182	98.5
WP_000072206.1\|1188275_1188446_+	hypothetical protein	Q4ZDV7	Staphylococcus_virus	3.3e-23	100.0
WP_144078953.1\|1188554_1189175_+	DUF4355 domain-containing protein	B2ZYY4	Staphylococcus_phage	7.1e-71	95.6
WP_000438502.1\|1189188_1190163_+\|capsid	phage major capsid protein	Q8SDU5	Staphylococcus_phage	1.3e-183	100.0
WP_001114091.1\|1190184_1190472_+	hypothetical protein	Q8SDU4	Staphylococcus_phage	6.2e-46	100.0
WP_000208960.1\|1190480_1190813_+\|head,tail	phage head-tail connector protein	A0A0F6N3F4	Staphylococcus_phage	5.5e-54	100.0
WP_001268312.1\|1190809_1191112_+	hypothetical protein	A4ZFB6	Staphylococcus_virus	1.1e-50	100.0
WP_001017815.1\|1191111_1191459_+	HK97 gp10 family phage protein	A0A0F6N3F5	Staphylococcus_phage	4.1e-60	100.0
WP_000188649.1\|1191470_1191854_+	hypothetical protein	A0A0F6N3L1	Staphylococcus_phage	1.5e-68	100.0
WP_031868818.1\|1191872_1192454_+\|tail	phage major tail protein, TP901-1 family	A0A0F6N3L8	Staphylococcus_phage	5.4e-105	99.5
WP_001100161.1\|1192515_1192881_+	hypothetical protein	A0A0F6N4J9	Staphylococcus_phage	3.6e-59	100.0
WP_000105584.1\|1192910_1193255_+	hypothetical protein	A0A0F6N3F7	Staphylococcus_phage	2.5e-57	100.0
WP_144078954.1\|1193271_1196736_+	hypothetical protein	A0EWT9	Staphylococcus_virus	4.9e-254	93.6
WP_024273334.1\|1196748_1197696_+\|tail	phage tail family protein	E0Y3M0	Staphylococcus_virus	8.0e-183	99.7
WP_144078955.1\|1197704_1199606_+\|tail	phage tail protein	Q8SDT5	Staphylococcus_phage	0.0e+00	99.8
WP_130826620.1\|1199620_1201531_+	hypothetical protein	A0A0F6N4K2	Staphylococcus_phage	0.0e+00	99.8
WP_050960853.1\|1201530_1203354_+\|plate	phage baseplate upper protein	A0A0F6N3G2	Staphylococcus_phage	0.0e+00	99.8
WP_000705896.1\|1203353_1203731_+	DUF2977 domain-containing protein	A0A0F6N3G4	Staphylococcus_phage	1.5e-60	100.0
WP_000782200.1\|1203734_1203908_+	XkdX family protein	A0A0F6N3L7	Staphylococcus_phage	6.6e-27	100.0
WP_000466777.1\|1203947_1204247_+	DUF2951 domain-containing protein	A0A0F6N3M6	Staphylococcus_phage	9.9e-47	100.0
WP_144078956.1\|1204383_1206282_+	glucosaminidase domain-containing protein	Q8SDT1	Staphylococcus_phage	0.0e+00	99.4
WP_144078957.1\|1206294_1207533_+\|plate	BppU family phage baseplate upper protein	Q4ZB96	Staphylococcus_virus	4.2e-208	98.8
WP_000387943.1\|1207537_1207933_+	hypothetical protein	A0A0H4IPB8	Staphylococcus_phage	8.8e-67	97.7
WP_000354128.1\|1207987_1208425_+\|holin	phage holin	S4SVG2	Staphylococcus_phage	4.1e-73	99.3
WP_001148121.1\|1208405_1209851_+	SH3 domain-containing protein	S4SVG5	Staphylococcus_phage	6.3e-296	100.0
WP_000448197.1\|1210458_1211046_+	hypothetical protein	Q4ZBG7	Staphylococcus_virus	5.4e-97	100.0
WP_000971220.1\|1211042_1211498_+	hypothetical protein	B7T0L3	Staphylococcus_virus	2.7e-72	100.0
WP_144078958.1\|1211667_1213605_-	heme uptake protein IsdB	NA	NA	NA	NA
WP_000160859.1\|1213807_1214860_-	LPXTG-anchored heme-scavenging protein IsdA	NA	NA	NA	NA
WP_000789821.1\|1215068_1215752_+	heme uptake protein IsdC	NA	NA	NA	NA
WP_001246701.1\|1215751_1216828_+	hypothetical protein	NA	NA	NA	NA
WP_001220199.1\|1216824_1217703_+	heme ABC transporter substrate-binding protein IsdE	NA	NA	NA	NA
WP_001566586.1\|1217712_1218681_+	iron ABC transporter permease	NA	NA	NA	NA
WP_001242420.1\|1218742_1219477_+	class B sortase	NA	NA	NA	NA
WP_000670950.1\|1219495_1219819_+	staphylobilin-forming heme oxygenase IsdG	NA	NA	NA	NA
WP_010956638.1\|1219855_1219963_+	hypothetical protein	NA	NA	NA	NA
WP_000435374.1\|1220202_1220943_+	RNA methyltransferase	NA	NA	NA	NA
WP_000003566.1\|1221323_1222382_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2I2L4E3	Orpheovirus	1.9e-31	35.5
WP_000908972.1\|1222381_1224784_+\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA

DBSCAN-SWA_6

1703838 : 1712168

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001213908.1\|1703838_1704624_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
WP_000924220.1\|1704749_1705640_-	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	3.4e-26	36.0
WP_001062177.1\|1705649_1706996_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
WP_000683932.1\|1707109_1708210_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
WP_000624585.1\|1708212_1708890_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_001283055.1\|1709020_1710127_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_001217235.1\|1710350_1712168_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	7.9e-54	36.0

DBSCAN-SWA_7

1781777 : 1790820

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364542.1\|1781777_1782296_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
WP_000594997.1\|1782317_1784591_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	3.1e-63	29.1
WP_000749795.1\|1784793_1787073_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_001160682.1\|1787347_1787608_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_001112045.1\|1787626_1788766_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_114288283.1\|1788788_1789814_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005768.1\|1789815_1790820_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_8

1914620 : 1992155

Staphylococcus_phage(94.83%)

tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001050541.1\|1914620_1921181_-	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	5.9e-301	96.8
WP_000836465.1\|1921506_1921818_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
WP_001789004.1\|1921839_1924263_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.7
WP_001025071.1\|1924550_1925732_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	6.2e-217	99.7
WP_000526539.1\|1925841_1926795_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_000764419.1\|1926791_1927355_+	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
WP_000757543.1\|1927474_1927876_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000266096.1\|1928449_1929277_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001790712.1\|1929279_1929399_-	hypothetical protein	NA	NA	NA	NA
WP_001196354.1\|1929510_1930512_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
WP_001008549.1\|1930633_1931098_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.5e-70	100.0
WP_001159035.1\|1931110_1932292_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.7e-227	100.0
WP_000493886.1\|1932302_1932935_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	6.4e-112	99.0
WP_000077351.1\|1932941_1933985_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.7e-197	99.7
WP_001261671.1\|1934465_1935968_-	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	1.5e-29	98.6
WP_000221179.1\|1936490_1936805_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	2.0e-53	100.0
WP_000989116.1\|1936804_1938097_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	1.1e-227	99.8
WP_001032833.1\|1938183_1939038_-	glucosaminidase domain-containing protein	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000384171.1\|1939313_1939538_-	hypothetical protein	NA	NA	NA	NA
WP_000671052.1\|1939736_1940207_+	RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	1.0e-82	99.4
WP_001153742.1\|1940319_1940763_+	competence protein ComK	NA	NA	NA	NA
WP_001030469.1\|1940749_1941193_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
WP_001168907.1\|1941488_1942124_+\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001096494.1\|1942563_1943277_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_000091445.1\|1943536_1943839_+	hypothetical protein	NA	NA	NA	NA
WP_001200542.1\|1944094_1944460_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
WP_000623476.1\|1944456_1944810_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	2.0e-22	98.3
WP_000453314.1\|1945192_1946026_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	5.4e-159	100.0
WP_000366158.1\|1946237_1947146_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	1.7e-137	99.0
WP_000933822.1\|1947270_1948464_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_000109910.1\|1948835_1950428_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.8
WP_016169057.1\|1950805_1951552_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	2.2e-143	99.2
WP_000672013.1\|1951556_1952030_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	7.2e-84	98.7
WP_000718107.1\|1952095_1952353_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000778532.1\|1952349_1953351_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	2.8e-186	97.9
WP_070044557.1\|1953355_1954834_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.7e-280	96.7
WP_072419835.1\|1954992_1955448_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	5.7e-78	97.3
WP_001793444.1\|1955750_1956401_+	excalibur calcium-binding domain-containing protein	A0A2H4PQM8	Staphylococcus_phage	3.0e-56	99.1
WP_000070649.1\|1956481_1957477_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	4.2e-73	97.2
WP_000669017.1\|1957550_1958177_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	3.6e-91	94.7
WP_000627541.1\|1958217_1958559_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	8.1e-53	92.0
WP_000414202.1\|1958659_1959232_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	3.3e-22	89.7
WP_000375477.1\|1960360_1960537_-	hypothetical protein	NA	NA	NA	NA
WP_000070811.1\|1960547_1960931_-	hypothetical protein	NA	NA	NA	NA
WP_001549059.1\|1961534_1961678_-\|transposase	transposase	A0A2H4PQU1	Staphylococcus_phage	6.4e-20	100.0
WP_001801861.1\|1961880_1961976_+	type I toxin-antitoxin system Fst family toxin PepA1	NA	NA	NA	NA
WP_001791893.1\|1962098_1962200_+	hypothetical protein	NA	NA	NA	NA
WP_001037045.1\|1962547_1962925_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_070044558.1\|1963445_1967558_-	ATP-binding protein	A0A2H4PQT3	Staphylococcus_phage	0.0e+00	99.9
WP_000072623.1\|1968407_1969607_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	1.6e-228	99.7
WP_000028669.1\|1969599_1971156_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	1.6e-289	100.0
WP_001791797.1\|1971319_1971454_-	hypothetical protein	NA	NA	NA	NA
WP_001038688.1\|1971518_1972238_-\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.1e-131	100.0
WP_001038759.1\|1972387_1973104_-\|protease	serine protease SplE	A0A2H4PQN5	Staphylococcus_phage	1.1e-131	100.0
WP_011447030.1\|1973205_1973313_+	hypothetical protein	NA	NA	NA	NA
WP_001038704.1\|1973261_1973981_-\|protease	serine protease SplD	A0A2H4PQP9	Staphylococcus_phage	4.6e-130	99.6
WP_001038865.1\|1974101_1974821_-\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	1.1e-131	100.0
WP_001039444.1\|1974878_1975601_-\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	6.4e-132	100.0
WP_001005059.1\|1975725_1976433_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	7.7e-130	99.6
WP_001092763.1\|1977396_1977963_+	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	3.3e-99	100.0
WP_000586140.1\|1978436_1979135_-	hypothetical protein	A0A2H4PQH0	Staphylococcus_phage	3.8e-113	94.4
WP_000581552.1\|1979131_1979893_-	lantibiotic immunity ABC transporter MutE/EpiE family permease subunit	A0A2H4PQH2	Staphylococcus_phage	4.4e-131	100.0
WP_001096791.1\|1979889_1980582_-	lantibiotic protection ABC transporter ATP-binding subunit	A0A2H4PQG7	Staphylococcus_phage	6.2e-124	100.0
WP_000691541.1\|1980604_1981978_-	S8 family serine peptidase	A0A2H4PQH1	Staphylococcus_phage	2.9e-258	100.0
WP_000504439.1\|1981987_1982506_-	flavoprotein	A0A2H4PQG9	Staphylococcus_phage	2.0e-95	100.0
WP_000566596.1\|1982521_1983766_-	lanthionine synthetase C family protein	A0A2H4PQH9	Staphylococcus_phage	5.1e-238	100.0
WP_001092606.1\|1983758_1986752_-	lantibiotic dehydratase	A0A2H4PQG8	Staphylococcus_phage	0.0e+00	97.1
WP_000416756.1\|1986816_1986960_-	gallidermin/nisin family lantibiotic	A0A2H4PQH4	Staphylococcus_phage	5.3e-14	80.9
WP_000416759.1\|1987696_1987840_-	gallidermin/nisin family lantibiotic	NA	NA	NA	NA
WP_000782464.1\|1988081_1989065_-	bi-component leukocidin LukED subunit D	A0A2H4PQH7	Staphylococcus_phage	2.3e-185	99.1
WP_000473596.1\|1989066_1990002_-	bi-component leukocidin LukED subunit E	A0A2H4PQI5	Staphylococcus_phage	1.4e-174	100.0
WP_001086056.1\|1990898_1991354_+	hypothetical protein	Q4ZCB9	Staphylococcus_virus	6.3e-61	76.2
WP_000206350.1\|1991366_1992155_+	DUF1828 domain-containing protein	A0A2H4PQI0	Staphylococcus_phage	5.3e-140	95.8

DBSCAN-SWA_9

2072207 : 2188221

132

Staphylococcus_phage(62.22%)

holin,terminase,protease,capsid,tRNA,tail,portal,plate,integrase,coat,head

attL 2170871:2170887|attR 2186183:2186199

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000545370.1\|2072207_2073635_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_000027917.1\|2073647_2075105_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_000170162.1\|2075106_2075409_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_000957020.1\|2075775_2077314_+	sodium/proline symporter PutP	NA	NA	NA	NA
WP_000831697.1\|2077402_2078602_-	CamS family sex pheromone protein	NA	NA	NA	NA
WP_000774565.1\|2078614_2080618_-	NAD-dependent DNA ligase LigA	A0A0K2QQN8	Ralstonia_phage	5.8e-114	36.1
WP_000992921.1\|2080621_2082814_-	DNA helicase PcrA	A7KV33	Bacillus_phage	1.0e-135	42.2
WP_000272070.1\|2082810_2083503_-	heptaprenylglyceryl phosphate synthase	NA	NA	NA	NA
WP_001165363.1\|2083674_2083977_-	hypothetical protein	NA	NA	NA	NA
WP_000572878.1\|2084085_2085381_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.6e-16	32.9
WP_000827761.1\|2086241_2087408_+\|protease	cysteine protease staphopain A	NA	NA	NA	NA
WP_000434534.1\|2087438_2087765_+	staphostatin A	NA	NA	NA	NA
WP_000669861.1\|2088056_2088230_-	NETI motif-containing protein	NA	NA	NA	NA
WP_000011542.1\|2088210_2088813_-	DUF2179 domain-containing protein	NA	NA	NA	NA
WP_000040866.1\|2089083_2089905_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	2.3e-69	52.7
WP_000284431.1\|2089897_2091367_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	4.5e-108	45.1
WP_000897635.1\|2091550_2092627_+	nitric oxide synthase oxygenase	NA	NA	NA	NA
WP_001177816.1\|2092646_2093441_+	prephenate dehydratase	NA	NA	NA	NA
WP_001802312.1\|2093512_2093620_+	hypothetical protein	NA	NA	NA	NA
WP_000323164.1\|2093630_2095193_-	SLC13 family permease	NA	NA	NA	NA
WP_070044646.1\|2095397_2096495_-	pectate lyase	U5PWM6	Bacillus_phage	1.3e-46	34.3
WP_000149686.1\|2096866_2097427_+	cysteine hydrolase	G3MA16	Bacillus_virus	2.0e-32	41.2
WP_001140871.1\|2097479_2098409_+	manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
WP_001790680.1\|2098603_2098777_-	hypothetical protein	NA	NA	NA	NA
WP_001021214.1\|2098828_2100208_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_144078984.1\|2100327_2101356_-	beta-propeller fold lactonase family protein	NA	NA	NA	NA
WP_000205106.1\|2101625_2102027_+	YolD-like family protein	U3PG23	Staphylococcus_phage	6.0e-23	42.9
WP_000267034.1\|2102599_2102773_-	hypothetical protein	NA	NA	NA	NA
WP_001188043.1\|2103223_2104264_+	linear amide C-N hydrolase	NA	NA	NA	NA
WP_000713072.1\|2104320_2105163_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_001033971.1\|2105159_2105717_-	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_000966288.1\|2105776_2106301_-	membrane protein	NA	NA	NA	NA
WP_000182842.1\|2106421_2106985_+	thioredoxin family protein	NA	NA	NA	NA
WP_001221657.1\|2107050_2107791_-	phenol-soluble modulin export ABC transporter permease subunit PmtD	NA	NA	NA	NA
WP_000763048.1\|2107790_2108663_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtC	A0A2H4PQG7	Staphylococcus_phage	6.1e-28	35.2
WP_000645726.1\|2108659_2109340_-	phenol-soluble modulin export ABC transporter permease subunit PmtB	NA	NA	NA	NA
WP_000991301.1\|2109340_2110237_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtA	A0A2H4PQG7	Staphylococcus_phage	1.1e-16	30.2
WP_000691584.1\|2110233_2110614_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000681968.1\|2110872_2111049_-	hypothetical protein	NA	NA	NA	NA
WP_000990056.1\|2111291_2111390_-	hypothetical protein	NA	NA	NA	NA
WP_144078985.1\|2111589_2112876_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_001792929.1\|2113199_2113490_-	MAP domain-containing protein	NA	NA	NA	NA
WP_144078986.1\|2113504_2114935_-	MAP domain-containing protein	NA	NA	NA	NA
WP_000688126.1\|2115772_2116750_+	GMP reductase	Q4ZCY7	Staphylococcus_virus	2.1e-186	100.0
WP_000675478.1\|2117105_2117942_-	hypothetical protein	D2JLG6	Staphylococcus_phage	8.4e-152	100.0
WP_144078987.1\|2118393_2119488_-	hypothetical protein	Q4ZCZ1	Staphylococcus_virus	3.7e-208	99.7
WP_144078988.1\|2120441_2120696_-\|holin	phage holin	Q4ZCZ3	Staphylococcus_virus	1.2e-40	98.8
WP_144079026.1\|2120897_2121074_-\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	8.5e-22	96.6
WP_000466774.1\|2121226_2121526_-	DUF2951 family protein	M9QRV2	Staphylococcus_phage	2.6e-31	100.0
WP_000916021.1\|2121571_2121736_-	XkdX family protein	Q4ZCZ6	Staphylococcus_virus	4.9e-24	100.0
WP_015978057.1\|2121728_2122118_-	DUF2977 domain-containing protein	Q4ZCZ7	Staphylococcus_virus	9.9e-63	100.0
WP_000067131.1\|2122117_2123584_-\|plate	phage baseplate upper protein	A0A2I6PE72	Staphylococcus_phage	1.5e-273	100.0
WP_000429552.1\|2123583_2125494_-	hypothetical protein	A0A2K9VBU3	Staphylococcus_phage	0.0e+00	100.0
WP_000179860.1\|2125509_2125800_-	hypothetical protein	A0A2I6PF46	Staphylococcus_phage	2.1e-49	100.0
WP_015978038.1\|2125799_2127383_-\|tail	phage tail protein	Q4ZD01	Staphylococcus_virus	9.3e-309	100.0
WP_001190533.1\|2127391_2128216_-\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	4.1e-159	100.0
WP_114288324.1\|2128215_2134392_-\|tail	phage tail tape measure protein	A0A2I6PDS2	Staphylococcus_phage	0.0e+00	98.4
WP_000438833.1\|2134405_2134564_-	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
WP_070055702.1\|2134605_2134956_-	hypothetical protein	A0A2I6PDE6	Staphylococcus_phage	2.3e-55	99.1
WP_070055703.1\|2135013_2135469_-	Ig domain-containing protein	A0A2I6PF45	Staphylococcus_phage	2.7e-75	97.4
WP_070055704.1\|2135560_2136202_-\|tail	phage tail protein	A0A2I6PEP6	Staphylococcus_phage	5.0e-120	99.5
WP_031822690.1\|2136236_2136632_-	DUF3168 domain-containing protein	A0A0K1LKC0	Staphylococcus_phage	1.1e-66	98.5
WP_144078989.1\|2136632_2137034_-	hypothetical protein	A0A0K1LL98	Staphylococcus_phage	8.9e-67	99.2
WP_070008557.1\|2137030_2137363_-	hypothetical protein	A0A2I6PDD6	Staphylococcus_phage	3.4e-56	97.3
WP_000050977.1\|2137374_2137653_-\|head,tail	phage gp6-like head-tail connector protein	R4WAL3	Staphylococcus_phage	3.5e-46	100.0
WP_031883907.1\|2137721_2138885_-\|capsid	phage major capsid protein	Q4ZCT8	Staphylococcus_virus	2.7e-217	99.5
WP_031883906.1\|2138896_2139670_-\|protease	Clp protease ClpP	A0A2I6PEQ7	Staphylococcus_phage	1.9e-134	97.7
WP_031773897.1\|2139653_2140892_-\|portal	phage portal protein	A0A2I6PF26	Staphylococcus_phage	1.7e-233	99.5
WP_015974521.1\|2140896_2142588_-\|terminase	terminase large subunit	Q9B0E3	Staphylococcus_virus	0.0e+00	100.0
WP_000778933.1\|2142577_2142883_-\|terminase	P27 family phage terminase small subunit	A0A2I6PEQ6	Staphylococcus_phage	2.9e-49	100.0
WP_015978060.1\|2143010_2143325_-	HNH endonuclease	Q4ZCU3	Staphylococcus_virus	2.5e-56	100.0
WP_000513702.1\|2143481_2143919_-	transcriptional regulator	B7T0I6	Staphylococcus_virus	6.1e-77	100.0
WP_015978040.1\|2143931_2145299_-	DEAD/DEAH box helicase	B7T0I5	Staphylococcus_virus	2.4e-265	100.0
WP_015978062.1\|2145279_2145570_-	VRR-NUC domain-containing protein	B7T0I4	Staphylococcus_virus	4.9e-51	100.0
WP_015978074.1\|2145703_2145808_+	hypothetical protein	A0A2I6PDP6	Staphylococcus_phage	2.7e-12	100.0
WP_114288325.1\|2145910_2148358_-	virulence-associated E family protein	B7T0I3	Staphylococcus_virus	0.0e+00	99.3
WP_000265258.1\|2148409_2148610_-	DUF1514 family protein	A0A2I6PF41	Staphylococcus_phage	2.9e-26	100.0
WP_015978069.1\|2148677_2148830_-	hypothetical protein	Q4ZCV4	Staphylococcus_virus	2.6e-19	100.0
WP_015978059.1\|2148826_2149183_-	ORF038	Q4ZCV5	Staphylococcus_virus	3.6e-59	100.0
WP_015978066.1\|2149179_2149386_-	DUF1381 domain-containing protein	Q4ZCV6	Staphylococcus_virus	4.2e-20	100.0
WP_144078990.1\|2149422_2149956_-	dUTP pyrophosphatase	A0A059T5A7	Staphylococcus_phage	4.3e-93	97.7
WP_031883691.1\|2149948_2150197_-	DUF1024 family protein	A7TWB0	Staphylococcus_phage	4.5e-37	98.8
WP_144078991.1\|2150189_2150546_-	acetyltransferase	A0A1X9H0B8	Staphylococcus_phage	1.6e-38	77.1
WP_000695750.1\|2150545_2150956_-	hypothetical protein	A0A1P8CN10	Staphylococcus_phage	2.1e-47	69.1
WP_144078992.1\|2150969_2151218_-	hypothetical protein	Q4ZCP1	Staphylococcus_virus	3.6e-42	98.8
WP_144078993.1\|2151226_2151427_-	hypothetical protein	C5I650	Staphylococcus_phage	3.7e-29	97.0
WP_060585274.1\|2151429_2151687_-	DUF3310 domain-containing protein	B5WZM8	Staphylococcus_phage	7.5e-43	98.8
WP_144078994.1\|2151686_2152088_-	PVL family protein	B7T0H0	Staphylococcus_virus	4.7e-68	99.2
WP_001164629.1\|2152087_2152273_-	DUF3113 family protein	A0A2I6PEM8	Staphylococcus_phage	7.0e-27	100.0
WP_078369548.1\|2152285_2154238_-	DNA polymerase	A0A0K1LKL8	Staphylococcus_phage	0.0e+00	98.6
WP_070046551.1\|2154307_2154865_-	DUF2815 family protein	A0A2K9VBT2	Staphylococcus_phage	4.1e-94	96.2
WP_070055761.1\|2154896_2155157_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_114288327.1\|2155169_2156336_-	DUF2800 domain-containing protein	B7T0G6	Staphylococcus_virus	1.7e-214	95.6
WP_114288328.1\|2156332_2156695_-	hypothetical protein	A7TWG3	Staphylococcus_phage	1.5e-52	95.0
WP_114288329.1\|2156709_2157033_-	TrmB family transcriptional regulator	A0A2I6PE70	Staphylococcus_phage	8.5e-52	99.1
WP_114288330.1\|2157111_2157273_-	DUF1270 domain-containing protein	A9CR58	Staphylococcus_phage	3.3e-20	94.3
WP_114288331.1\|2157269_2157590_-	DUF771 domain-containing protein	A0A2I6PDH6	Staphylococcus_phage	2.1e-55	98.1
WP_000939498.1\|2157740_2157884_-	hypothetical protein	W5R8I6	Staphylococcus_phage	2.5e-16	100.0
WP_095256790.1\|2157938_2158166_-	BetR domain protein	B5WZL3	Staphylococcus_phage	6.4e-30	90.7
WP_095256789.1\|2158336_2158948_+	helix-turn-helix domain-containing protein	B5WZL2	Staphylococcus_phage	9.3e-100	88.7
WP_015978049.1\|2159003_2159588_+	hypothetical protein	Q4ZCY3	Staphylococcus_virus	1.2e-67	100.0
WP_015978055.1\|2159672_2160098_+	hypothetical protein	Q4ZCY4	Staphylococcus_virus	4.7e-74	100.0
WP_114288339.1\|2160231_2160585_+	hypothetical protein	Q4ZCY5	Staphylococcus_virus	1.3e-13	100.0
WP_015978044.1\|2160651_2161689_+\|integrase	site-specific integrase	Q4ZCY6	Staphylococcus_virus	1.4e-180	100.0
WP_000595401.1\|2162807_2163824_-	bi-component leukocidin LukGH subunit G	A0A2I6PER8	Staphylococcus_phage	2.3e-26	29.3
WP_000791417.1\|2163845_2164898_-	bi-component leukocidin LukGH subunit H	A0A2I6PDF3	Staphylococcus_phage	1.6e-35	32.1
WP_000206623.1\|2165333_2166557_+	ArgE/DapE family deacylase	NA	NA	NA	NA
WP_000812008.1\|2166928_2167774_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000825510.1\|2167835_2168747_-	iron-hydroxamate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001045079.1\|2168907_2170215_+	TrkH family potassium uptake protein	NA	NA	NA	NA
2170871:2170887	attL	NA	NA	NA	NA
WP_086037433.1\|2172075_2173578_-	von Willebrand factor binding protein Vwb	NA	NA	NA	NA
WP_086037432.1\|2173838_2174189_-	complement inhibitor SCIN family protein	A7TWS0	Staphylococcus_phage	2.2e-21	53.8
WP_086037431.1\|2174345_2175335_-	adenosine deaminase	NA	NA	NA	NA
WP_086037430.1\|2175523_2176093_-\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	1.9e-99	97.4
WP_144078995.1\|2176089_2176431_-	pathogenicity island protein	A0A1W6JQM3	Staphylococcus_phage	1.6e-56	98.2
WP_118828201.1\|2176433_2176961_-\|coat	spore coat protein	Q4ZE87	Staphylococcus_phage	3.1e-83	92.0
WP_000214169.1\|2177013_2177667_-	hypothetical protein	Q4ZE82	Staphylococcus_phage	9.0e-117	100.0
WP_107536096.1\|2177697_2178039_-	pathogenicity island protein	Q4ZE66	Staphylococcus_phage	3.2e-57	98.2
WP_144078996.1\|2178574_2179216_-	pathogenicity island protein	Q4ZE67	Staphylococcus_phage	2.7e-113	95.8
WP_000356927.1\|2179212_2179593_-	hypothetical protein	Q4ZE71	Staphylococcus_phage	3.8e-67	96.8
WP_144078997.1\|2179922_2181623_-	DUF927 domain-containing protein	Q4ZE73	Staphylococcus_phage	6.4e-308	95.1
WP_117225041.1\|2181636_2182506_-	primase C-terminal domain-containing protein	Q4ZE74	Staphylococcus_phage	5.8e-164	95.8
WP_017431962.1\|2182572_2182893_-	DUF1474 family protein	A0A1W6JQH0	Staphylococcus_phage	1.8e-38	100.0
WP_017431963.1\|2182893_2183253_-	hypothetical protein	NA	NA	NA	NA
WP_001058497.1\|2183254_2183467_-	hypothetical protein	A0A1W6JPA6	Staphylococcus_phage	2.4e-18	72.1
WP_000708436.1\|2183459_2183606_-	hypothetical protein	NA	NA	NA	NA
WP_000481967.1\|2183602_2183920_-	helix-turn-helix domain-containing protein	A0A1W6JQE0	Staphylococcus_phage	9.2e-51	98.1
WP_000153640.1\|2183924_2184143_-	helix-turn-helix transcriptional regulator	A0A2H4JB11	uncultured_Caudovirales_phage	1.3e-19	66.7
WP_000620857.1\|2184315_2184990_+	helix-turn-helix transcriptional regulator	A0A2H4JGT9	uncultured_Caudovirales_phage	1.6e-39	45.8
WP_144078998.1\|2185003_2186176_+\|integrase	tyrosine-type recombinase/integrase	A0A1W6JQD3	Staphylococcus_phage	3.0e-219	97.7
WP_000240642.1\|2186244_2187861_-	chaperonin GroEL	A0A240F779	uncultured_virus	3.4e-157	54.7
2186183:2186199	attR	NA	NA	NA	NA
WP_000917289.1\|2187936_2188221_-	co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_AP019751

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection