CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP030090	Lactobacillus reuteri strain YSJL-12 plasmid unnamed1, complete sequence	0 crisprs	csa3	0	1
NZ_CP030091	Lactobacillus reuteri strain YSJL-12 plasmid unnamed2, complete sequence	0 crisprs	NA	0	0
NZ_CP030089	Lactobacillus reuteri strain YSJL-12 chromosome, complete genome	2 crisprs	cas3,cas14j,RT,DinG,DEDDh	2	10

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

17927 : 26420

Streptococcus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_016497301.1\|17927_18230_-	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	8.0e-20	46.9
WP_007124974.1\|18785_19403_+	CadD family cadmium resistance transporter	NA	NA	NA	NA
WP_016497300.1\|19419_19770_+	helix-turn-helix transcriptional regulator	E4ZFI8	Streptococcus_phage	1.0e-10	34.0
WP_016497299.1\|20030_20462_+	CopY/TcrY family copper transport repressor	NA	NA	NA	NA
WP_016497298.1\|20712_22866_+	copper-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	2.3e-60	30.4
WP_142499477.1\|22918_23083_+	DUF2933 domain-containing protein	NA	NA	NA	NA
WP_002817475.1\|23101_23398_+	hypothetical protein	NA	NA	NA	NA
WP_016497322.1\|23688_24267_+	recombinase family protein	A0A1J1J8Z4	Escherichia_phage	1.8e-23	33.3
WP_016497294.1\|24399_24813_+	recombinase family protein	A0A1J1J8Z4	Escherichia_phage	7.6e-05	31.0
WP_016497293.1\|25085_26420_-	NAD(P)/FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	1.0e-29	27.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP030089

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP030089_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030089_1

627985-628325

Orphan

Consensus_repeat	Method
AATTTAAATAATTGGGATACACATAATGT	CRISPRCasFinder
AAACAGTAAATTTAAATAATTGGGACACACATAATGTCACTAATATGGAAGAAATGTTT	PILER-CR

4 spacers

The CRISPR arrays of NZ_CP030089_1

>merge|NZ_CP030089|1|627985-628325|CRISPRCasFinder,PILER-CR
AATTTAAATAACTGGGATACTAGCAACGTTAAAGATATGTCATTTATGTTTTCTTCATCGAATTTAGTTGTCCCTGAGAGCATTGAGAACTGGGACACACATAATGTCACTAATATGGAAGGAATGTTTAGTGGGAATGATGCACTCCAATCATTAAATTTAAATAATTGGGATACACATAATGTTACTAATATGGCTTTAATGTTCCAAAACGAAGCAGCGTTAAAAACAGTTAATTTAAATAATTGGGACACACATAATGTCACTAATATGGAAGAAATGTTTGCAGGAACTCCCTCTTTAACAGATTTAAATCTAAGCAATTGGGATACTAGTAGCCT

>NZ_CP030089|1|1|627985-628325|CRISPRCasFinder
AATTTAAATAACTGGGATACTAGCAACGT	TAAAGATATGTCATTTATGTTTTCTTCATCGAATTTAGTTGTCCCTGAG
AGCATTGAGAACTGGGACACACATAATGT	CACTAATATGGAAGGAATGTTTAGTGGGAATGATGCACTCCAATCATTA
AATTTAAATAATTGGGATACACATAATGT	TACTAATATGGCTTTAATGTTCCAAAACGAAGCAGCGTTAAAAACAGTT
AATTTAAATAATTGGGACACACATAATGT	CACTAATATGGAAGAAATGTTTGCAGGAACTCCCTCTTTAACAGATTTA
AATCTAAGCAATTGGGATACTAGTAGCCT

>NZ_CP030089|1|1|628072-628269|PILER-CR
AACTGGGACACACATAATGTCACTAATATGGAAGGAATGTTTAGTGGGAATGATGCACT	CCAATCATTAAATTTAAAT
AATTGGGATACACATAATGTTACTAATATGGCTTTAATGTTCCAAAACGAAGCAGCGTT	AAAAACAGTTAATTTAAATAATTGGGACAC
ACATAATGTCACTAATATGGAAGAAATGTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030089.1\|WP_142499077.1\|631342_632209_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP030089.1\|WP_086132228.1\|616085_617555_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|181811
NZ_CP030089.1\|WP_003674708.1\|634488_636693_-\|ATP-dependent-Clp-protease-ATP-binding-subunit	unknown	unknown	gnl\|CDD\|223616
NZ_CP030089.1\|WP_003674706.1\|636969_637155_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030089.1\|WP_003664342.1\|637276_637543_+\|phosphocarrier-protein-HPr	unknown	unknown	gnl\|CDD\|237503
NZ_CP030089.1\|WP_003664372.1\|609540_610122_+\|dTDP-4-dehydrorhamnose-3,5-epimerase	unknown	unknown	gnl\|CDD\|376414
NZ_CP030089.1\|WP_142499078.1\|633828_634437_+\|ECF-transporter-S-component	unknown	unknown	gnl\|CDD\|227029
NZ_CP030089.1\|WP_142499075.1\|624088_626806_+\|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl\|CDD\|274741
NZ_CP030089.1\|WP_003674701.1\|639506_640724_+\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340844
NZ_CP030089.1\|WP_016496659.1\|611320_612160_+\|dTDP-4-dehydrorhamnose-reductase	unknown	unknown	gnl\|CDD\|367904
NZ_CP030089.1\|WP_063164438.1\|608657_609527_+\|glucose-1-phosphate-thymidylyltransferase-RfbA	unknown	unknown	gnl\|CDD\|130274
NZ_CP030089.1\|WP_003668625.1\|617741_619319_+\|peptide-chain-release-factor-3	unknown	unknown	gnl\|CDD\|179105
NZ_CP030089.1\|WP_016496665.1\|632953_633679_-\|MucBP-domain-containing-protein	unknown	unknown	gnl\|CDD\|377660
NZ_CP030089.1\|WP_063164447.1\|630981_631365_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224639
NZ_CP030089.1\|WP_142499073.1\|612231_614853_+\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|133475
NZ_CP030089.1\|WP_081120426.1\|619329_620442_+\|family-43-glycosylhydrolase	unknown	unknown	gnl\|CDD\|350097
NZ_CP030089.1\|WP_142499079.1\|637542_639273_+\|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl\|CDD\|224006
NZ_CP030089.1\|WP_142499074.1\|614924_616043_+\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NZ_CP030089.1\|WP_086132457.1\|610133_611174_+\|dTDP-glucose-4,6-dehydratase	unknown	unknown	gnl\|CDD\|224013
NZ_CP030089.1\|WP_063164449.1\|632208_632895_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP030089.1\|WP_142499077.1\|631342_632209_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	8.84995e-56
NZ_CP030089.1\|WP_086132228.1\|616085_617555_-\|transcriptional-regulator	gnl\|CDD\|181811	PRK09379, PRK09379, LytR family transcriptional regulator.	4.25958e-75
NZ_CP030089.1\|WP_003674708.1\|634488_636693_-\|ATP-dependent-Clp-protease-ATP-binding-subunit	gnl\|CDD\|223616	COG0542, clpA, ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP030089.1\|WP_003664342.1\|637276_637543_+\|phosphocarrier-protein-HPr	gnl\|CDD\|237503	PRK13780, PRK13780, phosphocarrier protein HPr; Provisional.	2.60359e-50
NZ_CP030089.1\|WP_003664372.1\|609540_610122_+\|dTDP-4-dehydrorhamnose-3,5-epimerase	gnl\|CDD\|376414	pfam00908, dTDP_sugar_isom, dTDP-4-dehydrorhamnose 3,5-epimerase. This family catalyze the isomerisation of dTDP-4-dehydro-6-deoxy -D-glucose with dTDP-4-dehydro-6-deoxy-L-mannose. The EC number of this enzyme is 5.1.3.13.	6.14476e-102
NZ_CP030089.1\|WP_142499075.1\|624088_626806_+\|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl\|CDD\|274741	TIGR03715, cell_surface_protein_precursor, KxYKxGKxW signal peptide. This model describes a novel form of signal peptide that occurs as an N-terminal domain with a recognizable motif, reminiscent of the YSIRK and PEP-CTERM forms of signal peptide. This domain tends to occur on long, low-complexity (usually Serine-rich and heavily glycosylated) proteins of the Firmicutes, and (as with YSIRK) the majority of these proteins have the LPXTG cell wall-anchoring motif at the C-terminus.	5.54896e-08
NZ_CP030089.1\|WP_003674701.1\|639506_640724_+\|glycosyltransferase-family-4-protein	gnl\|CDD\|340844	cd03817, GT4_UGDG-like, UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.	4.5205e-122
NZ_CP030089.1\|WP_016496659.1\|611320_612160_+\|dTDP-4-dehydrorhamnose-reductase	gnl\|CDD\|367904	pfam04321, RmlD_sub_bind, RmlD substrate binding domain. L-rhamnose is a saccharide required for the virulence of some bacteria. Its precursor, dTDP-L-rhamnose, is synthesized by four different enzymes the final one of which is RmlD. The RmlD substrate binding domain is responsible for binding a sugar nucleotide.	8.16161e-130
NZ_CP030089.1\|WP_063164438.1\|608657_609527_+\|glucose-1-phosphate-thymidylyltransferase-RfbA	gnl\|CDD\|130274	TIGR01207, Glucose-1-phosphate_thymidylyltransferase_1, glucose-1-phosphate thymidylyltransferase, short form. Alternate name: dTDP-D-glucose synthase homotetramer This model describes a tightly conserved but broadly distributed subfamily (here designated as short form) of known and putative bacterial glucose-1-phosphate thymidylyltransferases. It is well characterized in several species as the first of four enzymes involved in the biosynthesis of dTDP-L-rhamnose, a cell wall constituent and a feedback inhibitor of the enzyme. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NZ_CP030089.1\|WP_003668625.1\|617741_619319_+\|peptide-chain-release-factor-3	gnl\|CDD\|179105	PRK00741, prfC, peptide chain release factor 3; Provisional.	0
NZ_CP030089.1\|WP_016496665.1\|632953_633679_-\|MucBP-domain-containing-protein	gnl\|CDD\|377660	pfam06458, MucBP, MucBP domain. The MucBP (MUCin-Binding Protein) domain is found in a wide variety of bacterial proteins, in several repeats. The domain is found in bacterial peptidoglycan bound proteins and is often found in conjunction with pfam00746 and pfam00560.	1.95253e-08
NZ_CP030089.1\|WP_063164447.1\|630981_631365_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|224639	COG1725, COG1725, Predicted transcriptional regulators [Transcription].	9.86981e-28
NZ_CP030089.1\|WP_142499073.1\|612231_614853_+\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|133475	cd06583, PGRP, Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20 kDa) extracellular proteins; intermediate PGRPs (PGRP-I) that are 40-45 kDa and are predicted to be transmembrane proteins; and long PGRPs (PGRP-L), up to 90 kDa, which may be either intracellular or transmembrane. Several structures of PGRPs are known in insects and mammals, some bound with substrates like Muramyl Tripeptide (MTP) or Tracheal Cytotoxin (TCT). The substrate binding site is conserved in PGRP-LCx, PGRP-LE, and PGRP-Ialpha proteins. This family includes Zn-dependent N-Acetylmuramoyl-L-alanine Amidase, EC:3.5.1.28. This enzyme cleaves the amide bond between N-acetylmuramoyl and L-amino acids, preferentially D-lactyl-L-Ala, in bacterial cell walls. The structure for the bacteriophage T7 lysozyme shows that two of the conserved histidines and a cysteine are zinc binding residues. Site-directed mutagenesis of T7 lysozyme indicates that two conserved residues, a Tyr and a Lys, are important for amidase activity.	5.65684e-15
NZ_CP030089.1\|WP_081120426.1\|619329_620442_+\|family-43-glycosylhydrolase	gnl\|CDD\|350097	cd08983, GH43_Bt3655-like, Glycosyl hydrolase family 43 protein such as Bacteroides thetaiotaomicron VPI-5482 arabinofuranosidase Bt3655. This glycosyl hydrolase family 43 (GH43)-like family includes the characterized arabinofuranosidases (EC 3.2.1.55): Bacteroides thetaiotaomicron VPI-5482 (Bt3655;BT_3655) and Penicillium chrysogenum 31B Abf43B, as well as Bifidobacterium adolescentis ATCC 15703 beta-xylosidase (EC 3.2.1.37) BAD_1527. It belongs to the glycosyl hydrolase clan F (according to carbohydrate-active enzymes database (CAZY)) which includes family 43 (GH43) and 62 (GH62) families. GH43 includes enzymes with beta-xylosidase (EC 3.2.1.37), beta-1,3-xylosidase (EC 3.2.1.-), alpha-L-arabinofuranosidase (EC 3.2.1.55), arabinanase (EC 3.2.1.99), xylanase (EC 3.2.1.8), endo-alpha-L-arabinanases (beta-xylanases) and galactan 1,3-beta-galactosidase (EC 3.2.1.145) activities. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many GH43 enzymes display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	4.18635e-15
NZ_CP030089.1\|WP_142499079.1\|637542_639273_+\|phosphoenolpyruvate--protein-phosphotransferase	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
NZ_CP030089.1\|WP_142499074.1\|614924_616043_+\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	5.66834e-58
NZ_CP030089.1\|WP_086132457.1\|610133_611174_+\|dTDP-glucose-4,6-dehydratase	gnl\|CDD\|224013	COG1088, RfbB, dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane].	0
NZ_CP030089.1\|WP_142499078.1\|633828_634437_+\|ECF-transporter-S-component	gnl\|CDD\|227029	COG4684, COG4684, Predicted membrane protein [Function unknown].	3.82352e-16

>NZ_CP030089.1|WP_142499075.1|624088_626806_+|peptidoglycan-DD-metalloendopeptidase-family-protein
MENKKHFKLYKSGKKWIVATIITIAISTGIVFSENVLADTQQPQSTGQVQKINNPTNDQTYDHQDKGNYGYLDQANFNDNQLQVTGWQATNQSLDEQNRFVIAYDSTTNKELGRSKVINNVTRPDVAKVHNVYNAANSGYNSNIKLNTKNMQDENDSIQVVSRYSNTQTGEGQHTDWWSQPIEIDKSNYGSLDQFQVQNGQLSVAGWHATNGSINRDHHFLILFDQTASHEISRQEVKEVARPDVVRVYPNIMNADNSGFKAVFNVANLDPNHQYQILSRYSNAANGEGSYVTEWFAPRRIAPVNRVNEGWLDSFNISEPGQLTVAGWHASDLSNVASNRFIIIFDRTANRQVASMKINGIARPDVAKAYPHVFNAENAGFNVTFNLNSLQPGHQYSVVSRYSADPNGNGNDGQHIDFWSSPVTLNQTASYVDQVKMTDQGLHVQGWMASDNSLIQQNPYLIVLFDGKEITRQKLSLIARPDVGRVYPAMYGSAKSGFSTDIKLSTDQLNKLVNGNLQILLRFSAATDGNPYLNQGVTDQLSSNYSTNMGNANISLNGNNINIKGWHEAIGENSRPYQYLIVVGLDGHEFYRVKLDNTNSNLNSSNTSWLNNNKSSFAATLPVSAAMNHRGIKVLHRYTDDANGNGNYLDFWSPQIDINDGFQSLNGGIVYYDPVNGQLATGWRTINGNRYYFSDGYECQPDPDDLWVYNDQLHGRMYTGINWVDGHCYNFGNDGIARALPQNDGWSWPFPQSGEGWHYQGQKFGYTSNIRKNGYHDGLDFGTQDHPGSAVHAVHGGRVLDVNTVRDNNGQTMWWFTTIWDGRFLYVYQEAFSNRNKITVKPNDIIYAGQVIGYRDKDHLHLGINTSPNYGVDLKNSFVPSWSDSSKATGHGEWIDPEWAIRNRI
>NZ_CP030089.1|WP_081120426.1|619329_620442_+|family-43-glycosylhydrolase
MSAVTKKIRYLIYFGLVVVIFIICLMHKTTIRFIDENGASIITDQNVRLIKFPFVTHVNGYKQVSGIHYIQQDHQFVAKYKPEKNPLKQVKAAHFIGVTFQPTTVPITKGTQSDPFILSRQYDNGSRSGRDTLRILIGESYKKMKVLNANYPAVSVRDPSIMKQGNKYYIIYTRGLMSTTDFNHWEQINWSSVPGFDYSQDWAPEFVQGHDGKDYVIMSMQKKGNKHHQIMITSFNNGKIGKNWVEITGNLPINTIDPNLQYANGQYYLFCKNENTRKLVMGTSNNLTGPYKMERVQFDSSKYGSIEGPEAIIHNGIISLVFDTYDTQKNGTVSFHGLHYVERNVNGNRWSKMKKINSSIVTRHGQIILN
>NZ_CP030089.1|WP_003668625.1|617741_619319_+|peptide-chain-release-factor-3
MSPKELAEAVNKRRTFAIISHPDAGKTTITEQLLLFGGVVREAGTVKARKTGNFAKSDWMEIEKKRGISVTSSVMQFDFQGKRINILDTPGHEDFSEDTYRTLMAVDSAVMVIDSAKGIEPQTKKLFQICKMRGIPIFTFMNKFDRDAREPLDLLNEVEDVLGIETYPINWPIGSGHQFKGIYDRFNHRVALTHPADENNPYLPLDEDGNVEGDNPLAGDGEWQDAMDGMELVEVAGNELDQEKIAKGDQTPVFFGSALTNFGVQTFLETYLQFAPAPSDHKTEDGDVVKPLDPEFSGFVFKIQANMNPRHRDRIAFVRICSGEFDRGMDVTLSRTKKPMRLSNVTEFMADTRENVETAVAGDIIGLYDTGNFQIGDSIYNGKKDIQFEKLPQFTPELFVRVSAKNVMKQKSFHKGINQLVQEGAVQLYRSYSTGDYILGAVGQLQFEVFKFRMQNEYNSEVVMEPMGTKTARWIDPDQLDEKMSSSRNILVKDIHDQPLFLFENQFAENWFKQKYPDVKLTAKL
>NZ_CP030089.1|WP_086132228.1|616085_617555_-|transcriptional-regulator
MDNNNNNESREHYRKRMEERIQREVNERKRREREEAHNKRENRLRREEEQSSPDYQPPKKHHYRTPNWVRALIGLLICLVVAGGFYEYHKVHSVAKGVFGAGDGKISKKLQKGEPVSVLAMGTDVGALDRGNKGGNTDSLELFTINPKKKIITMTSIPRDILVRVETSDGPDYVKINAAYSINGPKQTVKQVSELLDVPIDYYAVINMGVLEKVVNSVGGVEVDNPFAFDYEGHHFKKGKQHLNGANALKYSRMRYDDPNNDYGRQKRQQQILKSVINKFKASGSIGAANKILDAVGDGVKTNIPIDDIATLYGNYHGAMNNVKTYHFQGQNATIEGVSFQIASPKEINRVSKLVRAQLGLKAKNVVNHETKMYKSQPHYNGYNETDFILPGGASYNDPGSGNGSDEVIGSSRSSRRSTNETESSSAYTAGNNESYSESRAVPATGNQTPTAPIQHHYSTPQYHTYNGYHSTYTQPTYGNHYGYTHRYY
>NZ_CP030089.1|WP_142499074.1|614924_616043_+|AI-2E-family-transporter
MSKQQFYHWLFWPLLLLTVATLIWMCTKIQFIFQPFLTFISVVFVPLIISGFLYYMLNPVLKLFMKIKIGRFHMNRGIASLLIVLLLIVIVVGGIAMLIPPVVKEISTLVRNMPQTVTGIQHLINDTIEHSFLRNVDLNAYYRQFDHQLAGYAQKVLQGLSTRVGDIIGMLTNVTVVTITVPVMLFYMLKDGSKLIPSIQKWLSPHHAKEVNDLLGKMNSTLSSYISGQMIECLFVGVFTSIGYVIIGQPLAIVLGIVAGLTNIIPYIGPYIGIAPALFVALTMAPNKIIWVIVVVIVVQQVDGNIVYPNIIGKTLQIHPLTIIMLLLAAGHIAGIGGMILCIPFYAVIKTVCEYFFDIYRIEHPVDKTKTE
>NZ_CP030089.1|WP_142499073.1|612231_614853_+|N-acetylmuramoyl-L-alanine-amidase
MEIKKHYKLYKDGKNWCAMALAVAAVSAGLVLGNTNVKADTPADNVPVVKTTNPTTGDANAELASQEKAAQAKDNGNYGYLDAAQVVNNNDLHVSGWQATNQAAGKDNRYLVAYDSTTNTELGRTSVTENVARPDVAKAYPDVVNAKDSGYQATMNNLDWSKVKSVDDQIHIVSRYSDAANGEGNHVDNWSQPINLDKGNYAYLDNFGVKDNQLQVSGWNATNKALGKANHYVILYDRTAGHEITRVKVEPTVRPDVAKAYSQVINAKDSGFNTAFSLASIDLNHELQIISRYSDAANGEGNYVSYWYAPQKFAPANTSNQGNLDSFNLSNGQLIVSGWHATDYSQVENNHYLILFDNTNKTQVKSIKVTNVARPDVAKAYPTVATARQSGFNANFGPVNLTPGYSYSLVSRYSTLDGGNGDNGQSKITDYWFNPVTLDQQATYVDSFTKTDNGYNVKGWMVSDQSINKPNAYLILLNDGQEIARTKVELTDRPDVAKVYPSIYNSQKSGFNGEFKVDSAKANGTLKVIMRFTGDDANKNFSDQYSQDYPTNAGNFDNIHVTASQVSLSGWHASTQAGNKPYEWLIVLDNNGQELYRQEITDKGLGRNDVQNVYPYIEGANKSGFQVTMNIPTKMQGHLVRFVHRLTDDKDGNGNFIDLSSNPVLVNLQYNLNENGINRYILNNHINHATITVNHVIPSDTTDVYSETEDGKPNMVVVHETANPNDSIWGEINYEKANYNKAFVHAFVDGNQIIEISPTDHEAWGAAYPANGRAVQFEQVEVYGANNFARELVNAAYYTAYKMNEYGMIPSLAQANGTGTLWSHHNVTQYIANGKTDHTDPDGYWANRASRYFGTSYTMKDFFELVKYEYSHL
>NZ_CP030089.1|WP_016496659.1|611320_612160_+|dTDP-4-dehydrorhamnose-reductase
MTKILITGANGQLGSELRNLLDERGIAYDAFDSKQMDITDQAVVNEKISALKPEVIYHCAAYTAVDNAEDVAKDLNWQVNADGTRNVAEAAKRVGAKMVYISTDYVFDGTNEGEYEVDAPTNPRNEYGKAKLAGEKAIQEILADYYIIRTSWVFGKYGKNFVYTMLRLAKDHDQLTVVNDQFGRPTWTRTLAEFMTYLVDHDQPFGTYQLSNENSCSWYEFATEILKDKDVEVAPVDSSAYPAKAYRPRHSVMSLKKAEDTGFEIIDWQTALNKFIEII
>NZ_CP030089.1|WP_086132457.1|610133_611174_+|dTDP-glucose-4,6-dehydratase
METFKNIIVTGGAGFIGSNFVHYVVNHHPEVEHITVLDKLTYAGNPANLDGLPKDKVELVVGDICDKDLVDQLVSKADAVVHYAAESHNDNSLIDPTPFIQTNIVGTSVLINACRKYDVRYHHISTDEVYGDLPLREDLPGHGEGKGEKFTPESPYRPSSPYSSSKASSDLLVRAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQITNILSGIRPKLYGSGKNVRDWIHTNDHSRAVWDILTKGKIGETYLIGADGEKNNKEVLEMILELMGQPKDAYDQVKDRPGHDLRYAIDATKLRTELGWEPEFTDFNTGLQHTIDWYTEHQDWWKDEKAAVEAKYAKNGQ
>NZ_CP030089.1|WP_003664372.1|609540_610122_+|dTDP-4-dehydrorhamnose-3,5-epimerase
MGKLNVQTTKLQDVKIITPAVFGDHRGFFEETYSDRDFKAAGIDFNFIQDNQSLSTQAGVLRGLHFQRGKAAQTKLIRVVTGAVLDVIVDLRKGSPTYKQWEGYILSASNHRQLLVPRGFAHGFLTLTDNVNFVYKCDNYYDAEADGGISFKTPELNIDWPIEFDKAITSEKDAAQPTLTEFEKDNPFVYGEI
>NZ_CP030089.1|WP_063164438.1|608657_609527_+|glucose-1-phosphate-thymidylyltransferase-RfbA
MKGIILAGGSGTRLYPITRGISKQLIPVYDKPMIYYPLSTLMLAGIRDILVISTPEYMPLFQELLGDGTNLGLNFSYKVQEKPNGLAEAFILGEDFIGDDSVCLILGDNIYYGAGLSDLVQSAAKKTDGATVFGYHVNDPERFGVVDFDDQMHALSIEEKPAHPKSNYAVTGLYFYDNQVVDIAKNIKPSDRGELEITDVNKEYLRQGKLDVKLMGRGYAWLDTGTHDSMLEAANFIATIEKRQNLKVASLEEIAYRMGYINKDQLVELAQPLKKNDYGQYLLRLAQQD
>NZ_CP030089.1|WP_063164447.1|630981_631365_+|GntR-family-transcriptional-regulator
MNFDFNDSMPLYQQIADQLEEMIFSGGFDEGSQVPSTTQLSQQLHINPATVLKGMNILVNKGLLEKRRGLGMFVKKGAQQKIMEQRKESFYNDYVKSLLVEAGKLGITKQHLLDLIERGENDGSINS
>NZ_CP030089.1|WP_142499077.1|631342_632209_+|ATP-binding-cassette-domain-containing-protein
MMDQLIVKNIVKKYRRQTVLDNISFTLEPAKIYGLLGRNGAGKTTLLNIMSNRIFPTSGEVKIGNEDVNNNDDLLSKIFLMSEVNLYPRHMKISQTFDLADAAYNNFDYDLANRLLKVFGLNDRMKITNLSTGQRTASKLIVALAVNADYVLLDEPILGLDANHRDSFYKELVKTYQERPRTFVLSTHLIEEIQQLVEHVLIMDQHHIIINEDTEGLLAKAYTISGPEKMVDEYTAGLKVLKTEMMGNIKTAYLLDRLDEQRVVPDQIKIGHYDLQHLFIYLTNGGEY
>NZ_CP030089.1|WP_063164449.1|632208_632895_+|hypothetical-protein
MKNQKRNLVISTMFQQAGDATGIALGWGLGIVLIIYLLELIISHNLESFLVSLQALPGIASSILNILLMALFLVTPYTDFKWAIQNGISRKTLWQGRILSLFLMTLAVWFIAQLVDLMNTPFDLASAWHSLLWYFGLSLTMMAIGNGFALLNRRWKWIVGIGLPMACLVLLMMLVYSLVGLIPALSASGVFKSIIISNITGWVILVVYLIIVYALARFFNNKIQLRRD
>NZ_CP030089.1|WP_016496665.1|632953_633679_-|MucBP-domain-containing-protein
MIDKFKTGNPIWVYYNDIDSGANLTVPQLLRGFIGQEYQIEQKQFPNYRYVKTEGETKGTFDMRQRIVHLFYRKQNWGEVQSIEMYLHLDAPTQIFDTAGGMPVGAPLPADITVKSFHRVATKNGQFWYEIGADQWIKYDQMHVVDNPFNQDIRKEKSKLINNLTVIPLKNVQAKVDYLHNKSINVYDAPYGNKVAEIPNGETITLIGKLNDNDEITWYQVGRKKYITSNYIQIEYPEDDE
>NZ_CP030089.1|WP_142499078.1|633828_634437_+|ECF-transporter-S-component
MTKTRHQQIRHNTTLAIFIAIILLQDFVPFFGNIPLGPLSITTLHVTVIIAAIVLGPVDGAIIGGIWGLLTWVRAFVAPSSPLAPLVFVNPLVSVVPRIMIGILAGYTFILMCRLIKAKYIAAVGAAIVGTLTNTGLVLGFIYLFYRTPAVAQTYGVNVNHLLIALETVMATNGLAELILAIIIVPMVALPVLEVRRRLEVS
>NZ_CP030089.1|WP_003674708.1|634488_636693_-|ATP-dependent-Clp-protease-ATP-binding-subunit
MQCQYCHQNPATIHLQMNFNGQRIQIDLCQNCYQKLQNLQTDMMNGGNGMNNFGFGSLEDFMNAMNNMQSQAAGANGQNMNGQSQRQGGGRNGKGILGQYGINLTDLARQGKIDPVIGRDNEIKRVIEILNRRTKNNPVLIGEAGVGKTAVVEGLAQAIVSGQVPEKLANKEIIRLDVVSLVQGTGIRGQFEKRMQQLMEEVRKNKNIILFIDEIHEIMGAGNAEGGMDAGNVLKPALARGDFQLVGATTLNEYRKIEKDAALARRFQPVEVDEPSVEETIRILNGIKSRYQDYHHVKYTDDAIVAAAKLSDRYIQDRYLPDKAIDLLDEAGSKKNLTLKNVDPNAIENEIHTAEAHKQQAADNQDYEKAAFYRDQVAKLEKAKKEAEENHTEDSATVTVKDMQRIVEERTNIPVGDLQKQEENQLRDLDKKLDEHVIGQTQAVDKVARAIRRNRIGLNKSGRPIGSFLFVGPTGVGKTETAKQLALQLFGSKDVMIRFDMSEYMDKTSTSKLIGAAPGYVGYEEAGQLTEQVRRHPYSLILLDEVEKAHPDVMHMFLQILDDGRLTDSQGRTVSFKDTIIIMTSNAGTGDSEASVGFGAESNGSTHSIIDKLTNYFKPEFLNRFDDIVQFNALSKDDLMKIVNLMIDDVNNMLTDKNLHIEVTNNVEEKLVDMGFDPKMGARPLRRVIQEQIEDRIADYVLDHSDAHKLVAKLDDNGDIVVEETEEVPTIAKK
>NZ_CP030089.1|WP_003674706.1|636969_637155_+|hypothetical-protein
MAEENFEQLLDDLRNKKIDHFVITPENFQQFQPIFHSYAYRSQIEGEAQRGGKIIYQLRER
>NZ_CP030089.1|WP_003664342.1|637276_637543_+|phosphocarrier-protein-HPr
MEKREFTITSETGIHARPATILVQAASKFSSDITLSYEGKSVNLKSIMGVMSLGVGQNAKVTITANGDDEKEALDTVAETMKKEGLTD
>NZ_CP030089.1|WP_142499079.1|637542_639273_+|phosphoenolpyruvate--protein-phosphotransferase
MSILLTGLAASSGITIAPAHLLVESDLSIKKQHTADENHEVARLHDSFALSKTELQHLSKRAHELLGQRAVTIIDTQIAILDDPTLQKKIIDRINSHHDTAEWAVKRVEDYYLSVFERKNDNEYLYARATALRDVTKRVLSHLLNVSLPDPGLLDHRAIFVANNITPTDTAQFDKRYVAGIVTTNGGRTSHFTIMSKTLSLPAVVGVKNATTIIHDGDLLIVDGIHGKVIVNPTNEEIEHYRLLAGKFIQEQQKWGALKDKQTVSADGRRFEVGANVGTFADVIDAQEDGAEGIGLLRTEFLYMSKDELPTEEQQFNAYKRFVSAMNEQRVVARTLDIGGDKKLGMVALPHEDNPYLGFRAIRIGLARPEILRPQLRALLRASVYGRLAIMFPMIATIEEFQAARAILDEEKEKLEQAGIQVAKNIEVGVMLEIPAVAVMAEHFAKYVDFFSIGSNDLIQYLFAVDRGNQQVAYLYQELHPAVLRMVRQVIEAAHAEGKWVGMCGEMANNAYAVPLLMAMGLDEFSMSSSQILRVRSLINQLNTRKLQPLVHRAIHAETAAAVQKLVEKYVPQVKL
>NZ_CP030089.1|WP_003674701.1|639506_640724_+|glycosyltransferase-family-4-protein
MNIGIFTDTYFPQVSGVATSIKTLRDELIAQGHHVYIFTTTDPKAKHDDVENGIYRFASIPFVSFSDRRIAVRGVFRAIKLAKKFQLDIVHNQTEFALGVMGKTVAKHLHIPCLHTYHTMYQDYLHYIANGHILKPNDVARLAHLYLKNISGIIAPSDRVLDTLTSYHVESPIRVIPTGINLRVYSKRDSAEEIANLRAKLGYGEETPVLLSLSRLAYEKNIHSLIEAMPDILAHKPDAQLLIVGDGPARHTLERQVREMQLNDNISFAGEISNDEVYHYYQMADVFVSASDSESQGLTYDEALASDLPIVVMRSEYTDQLIDDAAIGISFQKRADLVKGVLFYLNQPKNSESRLKRQQKLHEISAEVFVEKVVQFYQDCQNDMSVQDELNQTEKSHRLFHRPRS

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Crispr_ID: NZ_CP030089_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP030089_2

1853673-1854079

Orphan

Consensus_repeat	Method
GATGGGTTAGTAGGTGTTGTAGG	CRISPRCasFinder

7 spacers

The CRISPR arrays of NZ_CP030089_2

>merge|NZ_CP030089|2|1853673-1854079|CRISPRCasFinder
GCAGGTGTGGTTGGTGTTGTTGGTTGGTCACCCTTGTTATCTGTTGGCTTAGATGGTGTTACAGGGGTATCAGTGCCCTTGTTGCCGTTGTCTGGCTTTGCAGGGTTAGTAGGAGTTACAGGCTTATTACTCTTATTGTCGTCTGGCTTAGTAGGCGTTGTAGGGTTAGTAGGGGCTGTAGGATTAGTTGGCTTGTCATCACCCTTTGATGGGTTAGTAGGTGTTGTAGATTGATCACCCTTATTGTCGTCCTTACCAGTATTTGGCTTAGTAGGATTTGTAGGAGTGGTTGGGTTAGTTGGCTTATCGTCACCCTTTGATGGGTTAGTAGGTGTTGTAGGTTGATTACCCTTGTTGTTGTCATCCTTGCCAGTGTTAGGCTTAGATGGGTTAGTAGGGGTTGTAGG

>NZ_CP030089|2|2|1853673-1854079|CRISPRCasFinder
GCAGGTGTGGTTGGTGTTGTTGG	TTGGTCACCCTTGTTATCT
GTTGGCTTAGATGGTGTTACAGG	GGTATCAGTGCCCTTGTTGCCGTTGTCTGGCTTT
GCAGGGTTAGTAGGAGTTACAGG	CTTATTACTCTTATTGTCG
TCTGGCTTAGTAGGCGTTGTAGG	GTTAGTAGGGGCTGTAGGATTAGTTGGCTTGTCATCACCCTTT
GATGGGTTAGTAGGTGTTGTAGA	TTGATCACCCTTATTGTCGTCCTTACCAGTA
TTTGGCTTAGTAGGATTTGTAGG	AGTGGTTGGGTTAGTTGGCTTATCGTCACCCTTT
GATGGGTTAGTAGGTGTTGTAGG	TTGATTACCCTTGTTGTTGTCATCCTTGCCAGTGTTAGGCTTA
GATGGGTTAGTAGGGGTTGTAGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP030089.1\|WP_003675983.1\|1839988_1840327_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|185629
NZ_CP030089.1\|WP_003675989.1\|1841997_1843179_+\|IS66-family-transposase	unknown	unknown	gnl\|CDD\|376980
NZ_CP030089.1\|WP_003674676.1\|1850703_1852116_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368677
NZ_CP030089.1\|WP_063164275.1\|1864852_1866379_-\|lysine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234778
NZ_CP030089.1\|WP_016496813.1\|1843265_1844642_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP030089.1\|WP_063164274.1\|1863494_1864022_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030089.1\|WP_041821769.1\|1837607_1838324_-\|DUF3642-domain-containing-protein	unknown	unknown	gnl\|CDD\|371947
NZ_CP030089.1\|WP_003674674.1\|1866399_1867401_-\|tRNA-dihydrouridine-synthase-DusB	unknown	unknown	gnl\|CDD\|129820
NZ_CP030089.1\|WP_003675988.1\|1841086_1841587_-\|thiol-peroxidase	unknown	unknown	gnl\|CDD\|239312
NZ_CP030089.1\|WP_063164268.1\|1840430_1840799_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647
NZ_CP030089.1\|WP_063164272.1\|1861860_1862829_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030089.1\|WP_035161528.1\|1868519_1870628_-\|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	unknown	unknown	gnl\|CDD\|273520
NZ_CP030089.1\|WP_003675974.1\|1835895_1837395_-\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|225646
NZ_CP030089.1\|WP_142499391.1\|1855670_1855811_-\|transposase	unknown	unknown	gnl\|CDD\|377551
NZ_CP030089.1\|WP_003674673.1\|1867508_1868429_-\|Hsp33-family-molecular-chaperone-HslO	unknown	unknown	gnl\|CDD\|234643
NZ_CP030089.1\|WP_142499393.1\|1862821_1863511_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030089.1\|WP_063164271.1\|1860619_1861579_-\|beta-galactosidase	unknown	unknown	gnl\|CDD\|214988
NZ_CP030089.1\|WP_142499385.1\|1852153_1853122_-\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP030089.1\|WP_035161508.1\|1855800_1855989_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP030089.1\|WP_003675973.1\|1835005_1835836_-\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|163441

Protein	Function_ID	Function_description	E-value
NZ_CP030089.1\|WP_003675983.1\|1839988_1840327_-\|hypothetical-protein	gnl\|CDD\|185629	PTZ00450, PTZ00450, macrophage migration inhibitory factor-like protein; Provisional.	4.53205e-09
NZ_CP030089.1\|WP_003675989.1\|1841997_1843179_+\|IS66-family-transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	3.03712e-93
NZ_CP030089.1\|WP_003674676.1\|1850703_1852116_+\|hypothetical-protein	gnl\|CDD\|368677	pfam05935, Arylsulfotrans, Arylsulfotransferase (ASST). This family consists of several bacterial Arylsulfotransferase proteins. Arylsulfotransferase (ASST) transfers a sulfate group from phenolic sulfate esters to a phenolic acceptor substrate.	2.15779e-14
NZ_CP030089.1\|WP_063164275.1\|1864852_1866379_-\|lysine--tRNA-ligase	gnl\|CDD\|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0
NZ_CP030089.1\|WP_016496813.1\|1843265_1844642_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	3.71623e-43
NZ_CP030089.1\|WP_041821769.1\|1837607_1838324_-\|DUF3642-domain-containing-protein	gnl\|CDD\|371947	pfam12182, DUF3642, Bacterial lipoprotein. This domain family is found in bacteria, and is approximately 60 amino acids in length. There is a single completely conserved Y residue that may be functionally important. This domain is from a bacterial lipoprotein, a major virulence factor in Gram negative bacteria.	7.74962e-20
NZ_CP030089.1\|WP_003675988.1\|1841086_1841587_-\|thiol-peroxidase	gnl\|CDD\|239312	cd03014, PRX_Atyp2cys, Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a bacterial periplasmic peroxidase which differs from other PRXs in that it shows substrate specificity toward alkyl hydroperoxides over hydrogen peroxide. As with all other PRXs, the peroxidatic cysteine (N-terminal) of Tpx is oxidized into a sulfenic acid intermediate upon reaction with peroxides. Tpx is able to resolve this intermediate by forming an intramolecular disulfide bond with a conserved C-terminal cysteine (the resolving cysteine), which can then be reduced by thioredoxin. This differs from the typical 2-cys PRX which resolves the oxidized cysteine by forming an intermolecular disulfide bond with the resolving cysteine from the other subunit of the homodimer. Atypical 2-cys PRX homodimers have a loop-based interface (A-type for alternate), in contrast with the B-type interface of typical 2-cys and 1-cys PRXs.	2.95567e-63
NZ_CP030089.1\|WP_063164268.1\|1840430_1840799_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	6.71063e-27
NZ_CP030089.1\|WP_035161528.1\|1868519_1870628_-\|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	gnl\|CDD\|273520	TIGR01241, ATP-dependent_zinc_metalloprotease_FtsH, ATP-dependent metalloprotease FtsH. HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_CP030089.1\|WP_003675974.1\|1835895_1837395_-\|peptide-MFS-transporter	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	2.38271e-152
NZ_CP030089.1\|WP_142499391.1\|1855670_1855811_-\|transposase	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	6.50895e-12
NZ_CP030089.1\|WP_003674674.1\|1866399_1867401_-\|tRNA-dihydrouridine-synthase-DusB	gnl\|CDD\|129820	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family. This model represents one branch of COG0042 (Predicted TIM-barrel enzymes, possibly dehydrogenases, nifR3 family). This branch includes NifR3 itself, from Rhodobacter capsulatus. It excludes a broadly distributed but more sparsely populated subfamily that contains sll0926 from Synechocystis PCC6803, HI0634 from Haemophilus influenzae, and BB0225 from Borrelia burgdorferi. It also excludes a shorter and more distant archaeal subfamily.The function of nifR3, a member of this family, is unknown, but it is found in an operon with nitrogen-sensing two component regulators in Rhodobacter capsulatus.Members of this family show a distant relationship to alpha/beta (TIM) barrel enzymes such as dihydroorotate dehydrogenase and glycolate oxidase. [Unknown function, General].	7.90075e-130
NZ_CP030089.1\|WP_063164271.1\|1860619_1861579_-\|beta-galactosidase	gnl\|CDD\|214988	smart01038, Bgal_small_N, Beta galactosidase small chain. This domain comprises the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.	3.05405e-93
NZ_CP030089.1\|WP_142499385.1\|1852153_1853122_-\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	9.43513e-46
NZ_CP030089.1\|WP_003674673.1\|1867508_1868429_-\|Hsp33-family-molecular-chaperone-HslO	gnl\|CDD\|234643	PRK00114, hslO, Hsp33 family molecular chaperone HslO.	8.91683e-152
NZ_CP030089.1\|WP_003675973.1\|1835005_1835836_-\|metallophosphoesterase	gnl\|CDD\|163441	TIGR03729, acc_ester, putative phosphoesterase. Members of this protein family belong to the larger family pfam00149 (calcineurin-like phosphoesterase), a family largely defined by small motifs of metal-chelating residues. The subfamily in this model shows a good but imperfect co-occurrence in species with domain TIGR03715 that defines a novel class of signal peptide typical of the accessory secretory system.	2.00862e-118

>NZ_CP030089.1|WP_142499385.1|1852153_1853122_-|IS30-family-transposase
MTYKHLTTRELTLIADFWYQGTKAYRAAKLLQRSQETIYRVYRFLNDGKNIDQYLQTYQRHKRRCGRKQTQLPTIEVNYIHAQIKAGWTPDTIIGRHEHPISCSMRTLYRRFARNQYGFSVKQLPMKGKRHPNGYVEHRGKAGQLGRSIYQRYRDFPHYQHEFGHFEADTVQGKAHRGAVMTLVERQSKVMIVLNIHHKTDEAVNCQLDQWLAKLPRHFVKSITFDNGKEFAGWREIANKYDLHTYFAEVGAPNQRGLNENNNGLLRRDGLSKKLDFRDLPDELVTQLMHRRNNIPRKSLNYRTPLEVFLSHVTEEQLSPFF
>NZ_CP030089.1|WP_003674676.1|1850703_1852116_+|hypothetical-protein
MGQSIFPTGVTNFRPSKTWSGYTLFNAKNEGTILIDMNGKIVHEWKDLQGFPNKMINGGKVFGSLRCRKSSDAYQDYADLTEIDWDGNIRWSFTHNEEVTDQEIGKTWVARVHHDYQLEGNPVGYFVPGQETKDDFKKVLLLTHHDRKIGSISPYPLLDHVLLEIDRNGNKLWSWSTLDHFNDFPLTDEQKNAIFKNPNFQSASKEGDVFHINYASYLGPNKWFDQGDQRFKPNNILMGSREAMMSWIVDHDTGKIVWLLGPDFTKSFTLRNLGPLVGMHNVHLIPKGLPGAGNILALNNGGWAGYGAPNQTSSTGMRTTRIDGSEVIEFNPITLEKKWSFSAKDMGYKVAAHANYFYSPLQGSVQRLPNGNTLIDEGAGGRFLEVTPSHEIVWEYIYPYIADHLIYRAYRIPYDWIPQLSPSTEIAVTPPANSEFHLPGAADPSLNPITTVSVTGAYGYNKPSPAKNNN
>NZ_CP030089.1|WP_016496813.1|1843265_1844642_-|IS3-family-transposase
MTKISVKTKLKAVEEYANGNVTLASVRHKYGIAEHDFQIWVGIYARFGKGPLLNPPKVTGDFRLNLVKWKQENLASISETCIHFGYRSPGSVYQWERLYNKQGPQALLRLRRGRKPKNGQTTRQESRQASSAPKTEPNLTKRKLIVKDTTRCLKKIDSLEKASKKELAQVIYDLKAKYLLKDLIDALPISMSTYQYWQNRFEHPDEDEEELKAVIKGLFNYYQAEYGVRRLSTQIRDYYRLIGKKTPNHKRIQRLMHEMGLKCIKYNRRVRKYDSSKGPNGKKAKNKLNRRFMSNRKYQKMVCDITELKAHDGRKVYLEIIKDLATNQLLTWSISQHPNLQFALDPLQQLLKQLPHTGYQLTLHTDQGWHYQHRAWRKLLRQGNIRQSMSHRATCLDNAACETVFSKLKAEIGPDTSYRNQEELSQAINEWIHFYNERRIQTKLGNQTPLQYEQNLVA
>NZ_CP030089.1|WP_003675989.1|1841997_1843179_+|IS66-family-transposase
MKRIGQHIYSREARLKPAELYCVNLIQETYKCDECINSNGSEVLISSEMPQSLLPHSYFSSTILAKVAELKFNLALPFHRQIKLWQAIGLQVDARLLAANIIKVSQTYLEPLYDYLQGLVKTEPVIHMDETPFKVIDESNGNGYFWVTRSTKEFNKHQITMFHYYNTRAGKTIGQILGQQYSGVIMCDGYGGYSDRLYPQAKFGSCLVHIRREFYRITCLLKKEQLKNSKAYQVLQLMRPVFHEEKQLAYHTHKEKLVQRRLHVKPLMDKLYAYLENINFPQGRLRAAINNALKLKTRVYRIFEDGRVPLTNNPVEQAIRPSTLIRKNSLFAKSTAGAQANAIFYTLVATANQNHLNIYKYFKYLFDHLPNRKDEGLEAYLPWSKKVQTECHK
>NZ_CP030089.1|WP_003675988.1|1841086_1841587_-|thiol-peroxidase
MEITINGEKHQLVGNPPAIGDEFPHFKVFDKDNNKIKMKELLGKVTLLSVVPDINTPVCSIQTKHFNSTMDEFDEVNFLTISTNTIADQQKWCAAEGVKKMQLVSDAEESFGYESKLLIPDEGILARSVWILDKEGKVVYREIVDELVNEPKYDQAIAALRELLKK
>NZ_CP030089.1|WP_063164268.1|1840430_1840799_+|helix-turn-helix-transcriptional-regulator
MNQNEFDKKIKYFHENMPKQCPILYSMKIIGSKWKIPIMWYLMLNDGQHYNELKRSIGSITNTMLTKSLRELEEDGLLKRISKGTVPPSVTYHLTDTGKDLIYTMGDLFEWGKNLMEETQRN
>NZ_CP030089.1|WP_003675983.1|1839988_1840327_-|hypothetical-protein
MNEMPFIMSRVNIKISKNKELMLKKRLGLAIANVPGKSEKVLMVGFQDNYPLYLRGNGNEPLAYIEVSIFGTESHTGYEGLNTDITKAFYDILGIQLDHLYIKYDDISSWGV
>NZ_CP030089.1|WP_041821769.1|1837607_1838324_-|DUF3642-domain-containing-protein
MEVFIMRFSKAFLVATSIIAIGLYTSGCSSSSTSSNSSKSSSAQVSSVKKEESHIVGSYRDDADGAAITLNSDGTGTYVMANPTQADIHDQLTWKKEKNNYIINLNDSNYDTPIDARLNEDNLSLVGNDEWPNQSFKRVHGDFDVDNFLKEQHAKTSSSTTKDTHSKESSTHARAALKKWASDHHKDTNKIDNLKATTDLSEPDEGWAFVDDNGTEYAIVRNGKVYPRPVIDGGTSSN
>NZ_CP030089.1|WP_003675974.1|1835895_1837395_-|peptide-MFS-transporter
MSKQKNLDTSFFGQPRGLSTLFFTEMWERFSYYGMRAILLFYMYYAVTKGGLGMDQATAASIMSIYGSLVYLASVVGGWLSDRVWGSRRTVFIGGVLIMFGHIALSLPFGVSALYVSIALIVIGTGLLKPNVSEMVGGLYSPEDRRRDSGFSMFVFGINLGAAVAPWAVPWAANGFGLNLFHGEMNFHAGFSLAAIGMFFGLVQYVVDGRKYLSKDSLYPDDPIDKESLRPVIIWSIVGVVALVIILGLLAAMGQLNINNIITIITVIAIALPIYYFVMMLNSKKVTKDEKSRVVAYIPLFIAAAIFWAIEESGSVVLALFAEQRTILHIGGWHFAAANFQTLNPLFIMILTPFFVVLWDHWKKQPSAPGKFAAGLVIAGLSYVWMALPAMIHGTTAGRVSPFWLVGSWFIVEIAEMLISPIGLSVTTKLAPKAFKSQMMSMWFLADAAGQAVNAQVVKYYSSATEVPYFLIIGAVSIVFGLILCLFVKKIHGLMDGVD
>NZ_CP030089.1|WP_003675973.1|1835005_1835836_-|metallophosphoesterase
MKIAVSSDLHLDLNHADVAEIITQQAHYLTSHGIDHYFFVGDAFNDFEQTSAYFAELQSQLPTTKVHYLAGNHDMLKGVTYEQLENLDDDLYFHNRFIDIPQTNWRIIGNNGWYDYSFSTYKSNVKEVAQWKRAYWVDRSIMQPMNDPERMAIVLHQVEEALEQAHNQQKQVIFMTHFAPIREALPHPLIESVRRQRMWEMTTAMLGSRHLGALLAKFPEVKAVFYGHLHYAQPLITVGNIEYRNQAVGVRRKNSEDWKGESLLDQWISRLYTKKI
>NZ_CP030089.1|WP_142499391.1|1855670_1855811_-|transposase
MLINWHDPDHVYLVCGKTDLRKGIDGLAMVIAEKYGLELYDNSLFL
>NZ_CP030089.1|WP_035161508.1|1855800_1855989_-|hypothetical-protein
MEEKHDIVAPVFKAKGKPVSKAKISSRPVVKMKAGNIQLTIFKGTNPSLAAEIVKAVVHYAH
>NZ_CP030089.1|WP_063164271.1|1860619_1861579_-|beta-galactosidase
MAYTNKLHVIYGDGALGVAGDDFHYIFSYERGGLESMKIKGKEWLYRVPTPTFWRATTDNDRGNGFNVRSAQWVGADLFQKCVGIDLTVGDHHFDELPVAPRTNDFTGDEVTDGVVISYTFATLTIPSTHVTVSYEVQADGQIKVGVYYAGKAGLPELPVCGLRLIVPTEATGYTYAGLSGETYPDRMAGATRGTFTVKGLPVAKYLVPQENGMHMATDWVEITRNTTQNNADHDRAPFSLRVAKDDQPINFSCLPYTAEELENATHIEELPLARRTVLVVAGAVRGVGGIDSWGADVEEQYHIPADRDIEFSFLLNAK
>NZ_CP030089.1|WP_063164272.1|1861860_1862829_-|hypothetical-protein
MNSRIYTSIFNLKNITALEDIEQWRSEHCDDPVRHSKRHQEEFKRLPDGERNYRYSWNNIGEVESLPFSYGGKEINFVEASARIEYAKRKIFDSDHHYLPKKERTNLENIDIIFFEMNQKFFILIEESREKQIDRVLRLIGKANYEEVENLSSDFFNWLVYLYSENEGKLNSKIGITSISGFLGNVFDDENVVSSKSEETIKLIATRAFISTGGILREVKLNVDDSNNYNICFKMDDRCRTVISVNESVPYMTPNALEKGERLVLYMYTSLLPCLQKMFQAKKAGFKNKKKKFAKKIGLQVVKEIMDINNIHKDEIEPLDIN
>NZ_CP030089.1|WP_142499393.1|1862821_1863511_-|hypothetical-protein
MKSVFEALAKFLVGFLTAIIVSNKANILLKLLINMGIHNRSLQNTIVSLLVTFFVTCIVAILDYVYTNILFPMKINITSEQNEVKFKPNNNIYEPQRLNMHYEITPGGSLTMWMLKRLNVDLLVFFNPNYIDIALEEDKKWDFSGKEQEGLGFTEKMNQLHFLVLNSYFSEGKANKKYTVSVGMEICPKRIQNQEISLDYAMKSKKKMISTLLCKVHICDFKCKGVTDE
>NZ_CP030089.1|WP_063164274.1|1863494_1864022_-|hypothetical-protein
MKSYKILYQEDQHKNFSDYFKKENIDYIEGKINGSFAIQYNPQKLNSLLNEKEFFAKWIEYGIKQAIMTDQKFAFLILNLERIGISFLDCETNDGDNREIICDEDDRVSRELLLDLVSDEYKYILSATFFSKTHRNKIKLTQKGILHFEKSGEEIKTLIDIVNVGNEALNNEKCI
>NZ_CP030089.1|WP_063164275.1|1864852_1866379_-|lysine--tRNA-ligase
MSQELDQMRVRREKMEELKEAGIEPFGRRFKRDHLAQDLHDKFDQYDKEELNEMGAKVIIAGRMTRKRSSGKAGFADFVDRTGKIQVYARKDMVGDEPYHVFKRSDIGDFLGIEGDVIKTDTGELTVRAHKITFLSKALRPLPNKWDGVTDPETIYRQRYLDLISNPESFKRFHQRTAIIKAVRKYMDDNGFTEVETPILNTQAGGANARPFITHHNALDIDMYLRIATELYLKRLIVGGFERVYELGRIFRNEGMDPHHNPEFTTMETYAAYFDFQDVMDETEGIVKAAAKVVSDDGKITYQGHEIDLGGNFKRITMVDAVKEKTGIDFSDESMTDEDAKKLADEHKVEYKPYWTKGHILNAFFEEFVEDTLIQPTFVYEFPVEVSPLAKRNADNPAMTDRFELYVDGSELANAFSELNDPIDQKERFEMQAKEKANGNDEAEPVDLDYVQALEYGMPPTGGLGIGIDRLVMLLTDAKSIRDVILFPTMRPEKEQKNGSKKKKNNKK
>NZ_CP030089.1|WP_003674674.1|1866399_1867401_-|tRNA-dihydrouridine-synthase-DusB
MKWKIGNVEIPNQVVVAPMAGVTNSAFRVICKRFGAGYVVCEMISDRGIMYHNQRTLNMMDVDPEEHPMGIQIFGGTKETLVEAAKYVDQHTAADVIDINMGCPVNKVVKTDAGARWLLDPNKVYEMVSYVTDAVKKPVTVKMRTGWDDKHILAVENALAAERAGASAIAMHGRTRKQMYTGQADWNILKEVASQLKIPFMANGDVKTPEDAKKILDMTGATAAMIGRAAMGNPWMLKRTEHYLETGELLPEATPEQKIEMAKDHLNRLVDLKGEYVGVREFRGLSTYYIKGIPRAARTKVALVEAETLDEMNDIFDRFAEQTAERAAKRQQA
>NZ_CP030089.1|WP_003674673.1|1867508_1868429_-|Hsp33-family-molecular-chaperone-HslO
MKTTDYLVKSMTKDGKFRAYAVNATQVVQKAHEIHDTWSASSAALGRTLIGTILLATSSLQGEAGMTVKIQGNGPVGFIIADGTAEGTVKGYMGNPHVSLPANDKGKIDVAKAIGNQGTLSVTKMAPGDKTPYTGEVNLVSGELGDDFTYYLAQSEQIPSAVGLSVFVNPDENIDVAGGFMIQVMPGASDEEISKLEKTLKGLPLVSQMLRDGDTPEDILKKIFGDDLKILETMPVRYACDCSKERFAHALASISKDDMKKLIDEDHHAEAVCQFCGKKYEFNEDELKKIYAEMTANDDKNSTDEK
>NZ_CP030089.1|WP_035161528.1|1868519_1870628_-|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein
MNNNRKKNNFTHNVLFYAVMFLCIMGIAYFFFGGNTSTGQSKTVSQSEFISELKSNKVKSVQLQPNGGVYKVTGTYRKPQSNNDNSANNTGFALTPQRNNKVTQFQSSVLESDVTVSQLQNYANRHNVKISTRAEESNSVWMNLLLTVLPLVIMIFFFYMMMGQAGQGGGGRGVMSFGKTKAKPSDAKKNKVRFSDVAGEEEEKQELVEIVEFLKNPKKFTKLGARIPSGVLLEGPPGTGKTLLAKAVAGESGVPFFSISGSDFVEMFVGVGASRVRDLFDQAKKAAPAIIFIDEIDAVGRRRGNGMGGGHDEREQTLNQLLVEMDGFQGDEGIIVMAATNRSDVLDPALLRPGRFDRKILVGRPDVKGREAILRVHAKNKPMASDVDLKEIAKQTPGFVGADLANLLNEAALLAARRNKTEIDAADLDEAEDRVIAGPAKHNRVQSEQERKTVAYHEAGHTIVGLVLNDARVVHKVTIVPRGRAGGYAIMLPREDQMLMSKKNAMEQIAGLMGGRAAEELVFKSQSSGASNDFEQATQIARSMVTQYGMSDKIGPVELQSSGQVFTGQGYDQSPYSEKTAALVDEEVRRILTEGHETALHIIETHREQHKQIAEALLKYETLDEKQILSLYKTGKVPDKDVAAEDEEARAQTFEESKRELERLENERHDEAKDNQNDSSDAKSDNSNDSQSSDDSDDSEDK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP030089_1	1.6\|628209\|30\|NZ_CP030089\|PILER-CR	628209-628238	30	NZ_CP010872	Confluentimicrobium sp. EMB200-NS6 strain EMBL200_NS6 plasmid pNS6003, complete sequence	26197-26226	8	0.733
NZ_CP030089_1	1.6\|628209\|30\|NZ_CP030089\|PILER-CR	628209-628238	30	NZ_CP031599	Roseovarius indicus strain DSM 26383 plasmid pRIdsm_01, complete sequence	369955-369984	8	0.733
NZ_CP030089_1	1.6\|628209\|30\|NZ_CP030089\|PILER-CR	628209-628238	30	NZ_CP012662	Defluviimonas alba strain cai42 plasmid pcai42A, complete sequence	19455-19484	8	0.733
NZ_CP030089_1	1.6\|628209\|30\|NZ_CP030089\|PILER-CR	628209-628238	30	NZ_CP043620	Rhodobacteraceae bacterium SH-1 plasmid p2, complete sequence	37001-37030	8	0.733
NZ_CP030089_1	1.6\|628209\|30\|NZ_CP030089\|PILER-CR	628209-628238	30	NZ_CP004396	Celeribacter indicus strain P73 plasmid pP73C, complete sequence	43348-43377	8	0.733
NZ_CP030089_2	2.2\|1853738\|34\|NZ_CP030089\|CRISPRCasFinder	1853738-1853771	34	NZ_CP039697	Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence	133936-133969	10	0.706

1. spacer 1.6|628209|30|NZ_CP030089|PILER-CR matches to NZ_CP010872 (Confluentimicrobium sp. EMB200-NS6 strain EMBL200_NS6 plasmid pNS6003, complete sequence) position: , mismatch: 8, identity: 0.733

ctttaatgttccaaaacgaagcagcgttaa	CRISPR spacer
tctacatgtcccaagacgaagcagcgttcg	Protospacer
..*  ****.****.************* .

2. spacer 1.6|628209|30|NZ_CP030089|PILER-CR matches to NZ_CP031599 (Roseovarius indicus strain DSM 26383 plasmid pRIdsm_01, complete sequence) position: , mismatch: 8, identity: 0.733

ctttaatgttccaaaacgaagcagcgttaa	CRISPR spacer
tctacatgtcccaagacgaagcagcgttcg	Protospacer
..*  ****.****.************* .

3. spacer 1.6|628209|30|NZ_CP030089|PILER-CR matches to NZ_CP012662 (Defluviimonas alba strain cai42 plasmid pcai42A, complete sequence) position: , mismatch: 8, identity: 0.733

ctttaatgttccaaaacgaagcagcgttaa	CRISPR spacer
tctacatgtcccaagacgaagcagcgttcg	Protospacer
..*  ****.****.************* .

4. spacer 1.6|628209|30|NZ_CP030089|PILER-CR matches to NZ_CP043620 (Rhodobacteraceae bacterium SH-1 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.733

ctttaatgttccaaaacgaagcagcgttaa	CRISPR spacer
tctatatgtcccaagacgaagcagcgttcg	Protospacer
..*  ****.****.************* .

5. spacer 1.6|628209|30|NZ_CP030089|PILER-CR matches to NZ_CP004396 (Celeribacter indicus strain P73 plasmid pP73C, complete sequence) position: , mismatch: 8, identity: 0.733

ctttaatgttccaaaacgaagcagcgttaa	CRISPR spacer
tctacatgtcccaagacgaagcagcgttcg	Protospacer
..*  ****.****.************* .

6. spacer 2.2|1853738|34|NZ_CP030089|CRISPRCasFinder matches to NZ_CP039697 (Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence) position: , mismatch: 10, identity: 0.706

ggtatcagtgcccttgttgccgttgtctggcttt	CRISPR spacer
gtgatcggtgcccttgttgccgttttcgcgaaag	Protospacer
*  ***.***************** **  *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

19517 : 72665

Bacillus_phage(45.45%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010011610.1\|19517_20396_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	2.0e-42	36.4
WP_003688751.1\|20419_20707_-\|transposase	transposase	NA	NA	NA	NA
WP_003669506.1\|23562_23997_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_003675553.1\|24084_25734_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	4.1e-110	43.8
WP_003675551.1\|26078_26786_+	response regulator transcription factor	W8CYM9	Bacillus_phage	4.3e-40	39.6
WP_003675548.1\|26799_28665_+	cell wall metabolism sensor histidine kinase WalK	W8CYF6	Bacillus_phage	5.5e-34	34.7
WP_003675546.1\|28642_29938_+	hypothetical protein	NA	NA	NA	NA
WP_003675544.1\|29950_30793_+	hypothetical protein	NA	NA	NA	NA
WP_016496352.1\|30810_31617_+	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	5.6e-36	35.1
WP_063164302.1\|31720_33001_+	PDZ domain-containing protein	A0A1B1IT49	uncultured_Mediterranean_phage	6.2e-21	29.3
WP_003669518.1\|33092_33602_+	phosphatidylglycerophosphatase A	A0A291I9Q0	Lactobacillus_phage	8.2e-41	51.9
WP_003675538.1\|33910_34897_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_035161733.1\|35365_35845_+	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_003675532.1\|35988_36207_+	hypothetical protein	NA	NA	NA	NA
WP_003675530.1\|36274_36817_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_003675528.1\|37035_38208_+	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_019251835.1\|38275_39052_-	VOC family protein	NA	NA	NA	NA
WP_003675527.1\|39053_39866_-	NAD(P)-binding domain-containing protein	NA	NA	NA	NA
WP_063164304.1\|40166_41540_+	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_003675522.1\|41715_42798_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_003675520.1\|42799_43498_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.6e-37	37.9
WP_063164305.1\|43484_44720_+	ABC transporter permease	NA	NA	NA	NA
WP_016496365.1\|44859_45519_+	hypothetical protein	NA	NA	NA	NA
WP_142499005.1\|45584_46553_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_142499006.1\|46676_47627_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_003669548.1\|47771_48200_-	OsmC family protein	NA	NA	NA	NA
WP_063164307.1\|48267_49263_-	D-2-hydroxyacid dehydrogenase	A0A1J0F959	Only_Syngen_Nebraska_virus	1.4e-31	30.2
WP_016496371.1\|49264_50452_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_003670244.1\|50957_51179_+	hypothetical protein	NA	NA	NA	NA
WP_142499007.1\|51296_53534_+	AAA domain-containing protein	H6X3M6	Enterobacteria_phage	8.4e-122	39.4
WP_003675510.1\|54447_57342_+	hypothetical protein	NA	NA	NA	NA
WP_079375840.1\|57426_58053_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_016496373.1\|58150_59614_+	cardiolipin synthase	NA	NA	NA	NA
WP_016496374.1\|59728_63511_+	ATP-dependent nuclease subunit B	NA	NA	NA	NA
WP_003675503.1\|63510_67689_+	helicase-exonuclease AddAB subunit AddA	A7KV33	Bacillus_phage	1.2e-17	24.2
WP_142499008.1\|67689_68619_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_003668074.1\|68633_69602_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_016496376.1\|69767_70946_+	acetyl-CoA C-acetyltransferase	NA	NA	NA	NA
WP_142499009.1\|71246_72665_+\|transposase	ISLre2 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

115771 : 184196

unidentified_phage(15.79%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_142499013.1\|115771_118267_+\|transposase	IS3 family transposase	A0ZS58	Staphylococcus_virus	4.4e-63	39.1
WP_142499014.1\|118604_119735_+\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	5.7e-34	31.9
WP_003668074.1\|120369_121338_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_003675442.1\|121620_121872_+	hypothetical protein	NA	NA	NA	NA
WP_003675440.1\|121968_122649_+	response regulator transcription factor	W8CYM9	Bacillus_phage	2.5e-29	33.8
WP_142499015.1\|122645_123977_+	GHKL domain-containing protein	W8CYF6	Bacillus_phage	5.9e-22	27.6
WP_016496397.1\|124081_124732_+	Propeptide PepSY amd peptidase M4	NA	NA	NA	NA
WP_003669426.1\|126892_127213_-	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_003675433.1\|127338_127932_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_003675432.1\|128081_128762_+	hypothetical protein	NA	NA	NA	NA
WP_003675431.1\|128763_129738_+	hypothetical protein	NA	NA	NA	NA
WP_003675430.1\|129971_130844_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	2.1e-52	40.2
WP_003675429.1\|130946_131432_+	flavodoxin	NA	NA	NA	NA
WP_003675428.1\|131490_132360_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003675427.1\|132470_133007_+	acetyltransferase	NA	NA	NA	NA
WP_003675425.1\|133219_134080_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_016496402.1\|134186_134726_+	phenolic acid decarboxylase	NA	NA	NA	NA
WP_003675423.1\|134768_135299_+	PadR family transcriptional regulator	NA	NA	NA	NA
WP_003675422.1\|135274_135901_+	NAD(P)H-binding protein	NA	NA	NA	NA
WP_003670156.1\|136000_137002_+	DUF1002 domain-containing protein	NA	NA	NA	NA
WP_003675421.1\|137060_138050_-	asparaginase	NA	NA	NA	NA
WP_003675420.1\|139121_140000_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	8.0e-52	40.9
WP_016496405.1\|140100_140679_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_016496408.1\|141911_142556_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_003669411.1\|142661_143033_+	hypothetical protein	NA	NA	NA	NA
WP_003669410.1\|143134_143806_+	type 1 glutamine amidotransferase	NA	NA	NA	NA
WP_016496409.1\|143878_144679_-	EAL domain-containing protein	NA	NA	NA	NA
WP_016496411.1\|145089_146013_+\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	5.1e-33	31.3
WP_086120445.1\|146043_147153_+	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	1.2e-07	25.0
WP_003675410.1\|147168_147849_+	EAL domain-containing protein	NA	NA	NA	NA
WP_003675409.1\|147917_149216_-\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.3e-55	31.5
WP_016496414.1\|149235_150246_-	aspartate--ammonia ligase	A0A1C9C5F0	Heterosigma_akashiwo_virus	5.5e-65	43.4
WP_051111509.1\|150622_151240_-	folate family ECF transporter S component	NA	NA	NA	NA
WP_016496416.1\|151405_153937_-	M1 family metallopeptidase	A0A0P0IY26	Acinetobacter_phage	2.4e-64	25.2
WP_003675401.1\|154083_154725_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_003675399.1\|154941_156264_+	C1 family peptidase	R4TV59	Phaeocystis_globosa_virus	1.5e-65	31.0
WP_003675396.1\|156413_157589_+	MFS transporter	NA	NA	NA	NA
WP_016496417.1\|157600_158914_+	hypothetical protein	NA	NA	NA	NA
WP_016496420.1\|159424_160027_-	nitroreductase family protein	NA	NA	NA	NA
WP_016496421.1\|160124_160436_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003675390.1\|160563_161220_+	NAD(P)H-binding protein	NA	NA	NA	NA
WP_003675387.1\|161400_161838_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003669379.1\|161966_162200_+	cytochrome b5	NA	NA	NA	NA
WP_003665104.1\|162335_162554_+	cytochrome b5	NA	NA	NA	NA
WP_003675383.1\|162566_162812_+	cytochrome b5	NA	NA	NA	NA
WP_016496424.1\|162869_164006_-	5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase	A0A218MNE0	uncultured_virus	6.0e-84	45.5
WP_003675378.1\|164766_165723_+	ketopantoate reductase family protein	NA	NA	NA	NA
WP_080637861.1\|165906_167301_-	amino acid permease	NA	NA	NA	NA
WP_142499016.1\|167613_169269_+	MFS transporter	NA	NA	NA	NA
WP_142499017.1\|170576_171428_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	5.2e-16	25.2
WP_011953599.1\|171501_173307_-\|tRNA	threonine--tRNA ligase	A0A2K9L6B6	Tupanvirus	7.8e-86	32.1
WP_016496430.1\|173635_174319_-	hypothetical protein	NA	NA	NA	NA
WP_003675365.1\|174584_176177_-	divalent metal cation transporter	NA	NA	NA	NA
WP_003665087.1\|176749_177760_+	zinc-dependent alcohol dehydrogenase family protein	A0A2K9L7I1	Tupanvirus	3.1e-07	26.8
WP_003675363.1\|178021_178534_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_003675361.1\|178544_179603_+	ABC transporter permease	NA	NA	NA	NA
WP_003675359.1\|179620_180307_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.2e-32	37.6
WP_016496432.1\|180405_182388_+	ABC transporter ATP-binding protein/permease	G9BWD6	Planktothrix_phage	1.9e-32	40.7
WP_003675355.1\|182612_182849_+	hypothetical protein	NA	NA	NA	NA
WP_142499018.1\|183272_184196_+\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	1.1e-32	31.0

DBSCAN-SWA_3

602812 : 722885

109

Lactobacillus_phage(44.0%)

transposase,holin,terminase,integrase,portal,protease,tail,tRNA,head

attL 649370:649391|attR 723596:723617

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_063164433.1\|602812_603781_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_142499071.1\|603890_605021_-\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	5.1e-35	32.2
WP_142499072.1\|605308_607627_+	mannosyl-glycoprotein endo-beta-N-acetylglucosamidase	A0A249Y0X5	Enterococcus_phage	1.5e-33	39.8
WP_081372319.1\|607771_608251_+	DUF1828 domain-containing protein	Q6SEA4	Lactobacillus_prophage	4.5e-33	50.0
WP_142499436.1\|608254_608497_+	DUF1829 domain-containing protein	NA	NA	NA	NA
WP_063164438.1\|608657_609527_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	8.3e-102	60.1
WP_003664372.1\|609540_610122_+	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A1D8EQH2	Escherichia_phage	3.2e-33	41.7
WP_086132457.1\|610133_611174_+	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	3.2e-60	39.3
WP_016496659.1\|611320_612160_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	1.4e-34	40.1
WP_142499073.1\|612231_614853_+	N-acetylmuramoyl-L-alanine amidase	NA	NA	NA	NA
WP_142499074.1\|614924_616043_+	AI-2E family transporter	NA	NA	NA	NA
WP_086132228.1\|616085_617555_-	transcriptional regulator	NA	NA	NA	NA
WP_003668625.1\|617741_619319_+	peptide chain release factor 3	A0A1B0RXH7	Streptococcus_phage	6.3e-31	26.1
WP_081120426.1\|619329_620442_+	family 43 glycosylhydrolase	NA	NA	NA	NA
WP_142499075.1\|624088_626806_+	peptidoglycan DD-metalloendopeptidase family protein	E9LUJ4	Lactobacillus_phage	3.1e-30	41.6
WP_142499076.1\|627057_630840_+	BspA family leucine-rich repeat surface protein	NA	NA	NA	NA
WP_063164447.1\|630981_631365_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_142499077.1\|631342_632209_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	1.4e-21	32.0
WP_063164449.1\|632208_632895_+	hypothetical protein	NA	NA	NA	NA
WP_016496665.1\|632953_633679_-	MucBP domain-containing protein	NA	NA	NA	NA
WP_142499078.1\|633828_634437_+	ECF transporter S component	NA	NA	NA	NA
WP_003674708.1\|634488_636693_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A223W0B1	Agrobacterium_phage	6.7e-124	41.3
WP_003674706.1\|636969_637155_+	hypothetical protein	NA	NA	NA	NA
WP_003664342.1\|637276_637543_+	phosphocarrier protein HPr	NA	NA	NA	NA
WP_142499079.1\|637542_639273_+	phosphoenolpyruvate--protein phosphotransferase	A0A1V0SGR7	Hokovirus	2.2e-13	26.5
WP_003674701.1\|639506_640724_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_016496666.1\|640726_641755_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_003674698.1\|641754_642768_+	flippase-like domain-containing protein	NA	NA	NA	NA
WP_003664336.1\|642824_643073_+	YkuJ family protein	NA	NA	NA	NA
649370:649391	attL	NA	NA	NA	NA
WP_142499080.1\|649611_650736_-\|integrase	tyrosine-type recombinase/integrase	E9LUK6	Lactobacillus_phage	4.5e-108	56.2
WP_142499081.1\|651699_652158_-	hypothetical protein	NA	NA	NA	NA
WP_142499082.1\|652219_652861_-	helix-turn-helix domain-containing protein	U3PIS7	Lactobacillus_phage	9.0e-45	50.6
WP_122481370.1\|653009_653228_+	helix-turn-helix transcriptional regulator	A0A2H4JEA4	uncultured_Caudovirales_phage	3.5e-09	52.1
WP_142499083.1\|653243_653570_+	hypothetical protein	NA	NA	NA	NA
WP_086141145.1\|653726_653933_+	DNA-binding protein	NA	NA	NA	NA
WP_003664313.1\|654128_654344_+	hypothetical protein	NA	NA	NA	NA
WP_085680553.1\|654336_654609_+	hypothetical protein	NA	NA	NA	NA
WP_142499084.1\|654608_655088_+	siphovirus Gp157 family protein	A0A0A1EL06	Lactobacillus_phage	9.7e-44	56.6
WP_142499085.1\|655087_656458_+	DEAD/DEAH box helicase family protein	A0A0A1ENT0	Lactobacillus_phage	4.4e-214	79.6
WP_086142725.1\|656468_657233_+	AAA family ATPase	A0A0A1ENB5	Lactobacillus_phage	1.3e-127	87.8
WP_142499086.1\|657239_657755_+	DUF669 domain-containing protein	A0A0A1ELK1	Lactobacillus_phage	5.7e-74	77.2
WP_142499087.1\|657913_658705_+	DNA primase	A0A0A1ERC1	Lactobacillus_phage	1.3e-122	82.2
WP_142499438.1\|658706_659921_+	helicase	A0A0A1EL11	Lactobacillus_phage	2.9e-169	70.4
WP_142499088.1\|660170_660383_+	hypothetical protein	NA	NA	NA	NA
WP_142499089.1\|660385_660586_+	hypothetical protein	NA	NA	NA	NA
WP_142499090.1\|660585_660939_+	VRR-NUC domain-containing protein	A0A0A1ENT6	Lactobacillus_phage	6.4e-53	86.5
WP_085678666.1\|660935_661118_+	hypothetical protein	NA	NA	NA	NA
WP_142499091.1\|661136_661538_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_142499092.1\|661646_661835_+	hypothetical protein	NA	NA	NA	NA
WP_142499093.1\|661837_662059_+	hypothetical protein	NA	NA	NA	NA
WP_142499094.1\|662058_662286_+	hypothetical protein	NA	NA	NA	NA
WP_142499095.1\|662455_662668_+	hypothetical protein	NA	NA	NA	NA
WP_142499096.1\|662667_663108_+	hypothetical protein	NA	NA	NA	NA
WP_142499097.1\|663262_663724_+	ArpU family transcriptional regulator	D2IYV6	Enterococcus_phage	3.7e-08	34.3
WP_142499098.1\|663921_664530_+	DUF4145 domain-containing protein	Q20DE2	Lactobacillus_phage	7.7e-70	60.9
WP_142499099.1\|664648_665236_+	hypothetical protein	NA	NA	NA	NA
WP_142499100.1\|665274_665709_+\|terminase	terminase small subunit	Q37950	Lactococcus_phage	1.8e-25	53.0
WP_142499101.1\|665837_667103_+\|terminase	PBSX family phage terminase large subunit	A0A0A1ELG3	Lactobacillus_phage	1.8e-209	81.9
WP_142499102.1\|667114_668551_+\|portal	phage portal protein	A0A0A1ER87	Lactobacillus_phage	9.3e-175	67.3
WP_142499103.1\|668534_669980_+\|head	phage head morphogenesis protein	A0A0A1EKX3	Lactobacillus_phage	1.5e-76	45.2
WP_142499104.1\|670226_670841_+	DUF4355 domain-containing protein	A0A0P0ID10	Lactobacillus_phage	2.1e-14	31.9
WP_142499105.1\|670855_671734_+	hypothetical protein	A0A0A1ELG8	Lactobacillus_phage	9.0e-88	60.3
WP_142499106.1\|671742_672138_+\|head,tail	phage head-tail connector protein	A0A0A1ER91	Lactobacillus_phage	3.0e-35	62.7
WP_142499107.1\|672115_672430_+	hypothetical protein	A0A0N7IR97	Lactobacillus_phage	2.1e-15	46.5
WP_086131549.1\|672413_672821_+	hypothetical protein	A0A0A1ENQ3	Lactobacillus_phage	5.2e-22	48.4
WP_142499108.1\|672829_673222_+	DUF3168 domain-containing protein	Q77K20	Lactococcus_phage	1.2e-07	31.0
WP_142499109.1\|673234_673822_+\|tail	phage tail protein	A0A0A1ELH3	Lactobacillus_phage	1.1e-46	51.6
WP_142499110.1\|673836_674172_+	hypothetical protein	A0A0A1ER95	Lactobacillus_phage	1.3e-15	45.6
WP_086131578.1\|674267_674591_+	hypothetical protein	A0A0P0ID51	Lactobacillus_phage	5.6e-19	48.5
WP_142499111.1\|674590_677212_+	tape measure protein	A0A1P8BLX4	Lactococcus_phage	1.3e-89	46.5
WP_142499112.1\|677208_677988_+\|tail	phage tail protein	Q6SEC3	Lactobacillus_prophage	9.2e-52	45.1
WP_142499113.1\|677987_680426_+	peptidoglycan DD-metalloendopeptidase family protein	Q6SEC2	Lactobacillus_prophage	1.3e-144	39.4
WP_142499114.1\|683135_683318_+	hypothetical protein	NA	NA	NA	NA
WP_142499115.1\|683318_683471_+	XkdX family protein	NA	NA	NA	NA
WP_142499116.1\|683801_684059_+	hypothetical protein	NA	NA	NA	NA
WP_142499117.1\|684124_684559_+\|holin	phage holin family protein	NA	NA	NA	NA
WP_142499118.1\|684558_685518_+	glycoside hydrolase family 25	Q6SE63	Lactobacillus_prophage	3.1e-57	40.1
WP_003675868.1\|686409_686964_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_016496667.1\|687002_688400_-	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_016496668.1\|688793_691028_+	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	2.3e-249	59.4
WP_003675861.1\|691093_691672_+	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A0C5K925	Enterococcus_phage	2.8e-53	59.7
WP_142499119.1\|691683_692574_+	hypothetical protein	NA	NA	NA	NA
WP_016496669.1\|692957_693767_+	LysM peptidoglycan-binding domain-containing protein	A0A0E3XCL7	Enterococcus_phage	1.1e-23	71.1
WP_142499120.1\|693922_695623_+	phosphoenolpyruvate carboxykinase	NA	NA	NA	NA
WP_003664230.1\|695952_696660_+	LysM peptidoglycan-binding domain-containing protein	A0A096XT26	Enterococcus_phage	5.5e-27	45.8
WP_016496673.1\|696788_697637_-	aldo/keto reductase	NA	NA	NA	NA
WP_003664225.1\|697769_698201_+	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
WP_142499121.1\|698327_699830_+	LytTR family transcriptional regulator	Q6DMX4	Streptococcus_phage	1.9e-32	26.7
WP_142499122.1\|699829_700276_+	hypothetical protein	NA	NA	NA	NA
WP_003664221.1\|702104_702629_-	membrane protein	NA	NA	NA	NA
WP_019251755.1\|703120_703732_-	VanZ family protein	NA	NA	NA	NA
WP_142499123.1\|703822_705169_+	amino acid permease	NA	NA	NA	NA
WP_003675841.1\|705381_705837_-	transcriptional repressor	NA	NA	NA	NA
WP_003675840.1\|705960_707400_+	MFS transporter	NA	NA	NA	NA
WP_003675838.1\|707485_708025_+	DNA-3-methyladenine glycosylase I	NA	NA	NA	NA
WP_003670795.1\|708185_709373_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	4.7e-148	67.7
WP_003675835.1\|709694_712115_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	68.5
WP_003675833.1\|712176_712440_+	hypothetical protein	NA	NA	NA	NA
WP_016496675.1\|712554_714204_+	polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_142499124.1\|714268_715129_-	NAD(P)H-hydrate dehydratase	NA	NA	NA	NA
WP_142499125.1\|715217_716621_+	dipeptidase PepV	NA	NA	NA	NA
WP_003675826.1\|716645_717158_+	universal stress protein	NA	NA	NA	NA
WP_003675824.1\|717246_718293_+	mannosyl-glycoprotein endo-beta-N-acetylglucosamidase	A0A249Y0X5	Enterococcus_phage	9.0e-10	32.2
WP_003664204.1\|718327_718960_-	deoxynucleoside kinase	C1KFI3	Lactobacillus_virus	2.1e-46	46.4
WP_142499126.1\|719175_719784_+	hypothetical protein	NA	NA	NA	NA
WP_003675820.1\|719865_720882_+	LacI family transcriptional regulator	NA	NA	NA	NA
WP_003675819.1\|720938_721862_+	ribokinase	NA	NA	NA	NA
WP_003668533.1\|721978_722224_+	hypothetical protein	NA	NA	NA	NA
WP_003675817.1\|722207_722885_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
723596:723617	attR	NA	NA	NA	NA

DBSCAN-SWA_4

783258 : 839634

Lactobacillus_phage(66.67%)

terminase,integrase,capsid,portal,tail,tRNA

attL 784430:784445|attR 834669:834684

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_142499132.1\|783258_784305_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2I2L4E3	Orpheovirus	1.0e-29	33.2
WP_016496708.1\|784311_786729_+\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
784430:784445	attL	NA	NA	NA	NA
WP_003675714.1\|786914_787553_+	C40 family peptidase	M9MUG9	Rhodococcus_phage	2.7e-09	34.1
WP_003668449.1\|787665_788322_+	uridine kinase	A0A1V0SAA3	Catovirus	2.7e-36	37.1
WP_003664064.1\|788385_788862_+	transcription elongation factor GreA	NA	NA	NA	NA
WP_003675710.1\|789770_790160_+	heme biosynthesis protein HemY	NA	NA	NA	NA
WP_003675709.1\|790227_792843_-	YfhO family protein	NA	NA	NA	NA
WP_142499133.1\|793052_795152_+	penicillin-binding protein 2	NA	NA	NA	NA
WP_003664049.1\|795290_795440_+	50S ribosomal protein L33	NA	NA	NA	NA
WP_003675704.1\|795576_796131_+	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_003668441.1\|796680_796920_+	YqgQ family protein	NA	NA	NA	NA
WP_003675699.1\|796944_797916_+	ROK family glucokinase	NA	NA	NA	NA
WP_003672480.1\|797929_798349_+	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_003675697.1\|798509_798686_-	DUF3042 family protein	NA	NA	NA	NA
WP_003675695.1\|798800_799724_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_003675693.1\|799893_801237_+	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_003675691.1\|801478_802984_+\|tRNA	glutamate--tRNA ligase	A0A2K9L0I5	Tupanvirus	1.3e-09	31.9
WP_003675688.1\|803096_804278_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_003675687.1\|804963_805815_+	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_142499134.1\|805928_807134_-\|integrase	tyrosine-type recombinase/integrase	A9D9I9	Lactobacillus_prophage	3.9e-65	39.8
WP_142499135.1\|807216_807588_-	transporter	A0A0P0I7G8	Lactobacillus_phage	2.4e-26	51.7
WP_142499136.1\|807599_808103_-	DUF4352 domain-containing protein	A0A0P0IXE0	Lactobacillus_phage	1.3e-27	51.6
WP_142499137.1\|808197_808635_-	ImmA/IrrE family metallo-endopeptidase	A0A0S2MV59	Bacillus_phage	2.7e-16	37.6
WP_142499138.1\|808647_809121_-	helix-turn-helix domain-containing protein	Q0H244	Geobacillus_phage	7.9e-22	43.4
WP_019251658.1\|809263_809467_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_034540199.1\|809705_810086_-	DUF2513 domain-containing protein	A0A0P0IV09	Lactobacillus_phage	1.0e-24	42.4
WP_142499139.1\|810639_810870_+	hypothetical protein	NA	NA	NA	NA
WP_142499140.1\|811003_811207_+	hypothetical protein	NA	NA	NA	NA
WP_142499141.1\|811203_811383_+	hypothetical protein	NA	NA	NA	NA
WP_142499142.1\|811592_811871_+	hypothetical protein	NA	NA	NA	NA
WP_142499143.1\|812764_813625_+	hypothetical protein	E9LUM4	Lactobacillus_phage	6.0e-68	46.7
WP_142499144.1\|813636_814485_+	DnaD domain protein	NA	NA	NA	NA
WP_142499145.1\|814488_814818_+	hypothetical protein	NA	NA	NA	NA
WP_142499146.1\|814814_815333_+	hypothetical protein	NA	NA	NA	NA
WP_142499147.1\|815329_816022_+	phage regulatory protein	E9LUT0	Lactobacillus_phage	5.4e-27	52.0
WP_142499148.1\|816035_816533_+	hypothetical protein	NA	NA	NA	NA
WP_142499149.1\|816522_816738_+	hypothetical protein	NA	NA	NA	NA
WP_142499092.1\|816734_816923_+	hypothetical protein	NA	NA	NA	NA
WP_142499150.1\|816925_817147_+	hypothetical protein	NA	NA	NA	NA
WP_142499151.1\|817146_817341_+	hypothetical protein	NA	NA	NA	NA
WP_142499152.1\|817618_817810_+	hypothetical protein	NA	NA	NA	NA
WP_142499153.1\|817919_818435_+	hypothetical protein	A0A0A1EL23	Lactobacillus_phage	5.8e-10	32.0
WP_142499154.1\|819448_820147_+	phosphoadenosine phosphosulfate reductase family protein	NA	NA	NA	NA
WP_142499155.1\|820149_820575_+	hypothetical protein	NA	NA	NA	NA
WP_142499156.1\|820588_820972_+	hypothetical protein	NA	NA	NA	NA
WP_142499157.1\|820985_821771_+	ParB N-terminal domain-containing protein	A0A1B1P7B5	Bacillus_phage	1.8e-15	42.7
WP_142499158.1\|821865_822369_+	hypothetical protein	NA	NA	NA	NA
WP_142499159.1\|822337_823642_+\|terminase	PBSX family phage terminase large subunit	A4L7R3	Lactococcus_phage	1.1e-174	65.7
WP_142499160.1\|823692_824478_+	DUF2116 family Zn-ribbon domain-containing protein	A0A0P0HRI2	Lactobacillus_phage	1.7e-21	38.9
WP_142499161.1\|824529_826089_+\|portal	phage portal protein	U3PCP8	Lactobacillus_phage	3.5e-135	49.0
WP_142499162.1\|826091_827243_+\|capsid	capsid protein	O03929	Lactobacillus_phage	3.9e-91	50.9
WP_142499163.1\|827342_827912_+	scaffolding protein	L0P7B0	Lactobacillus_phage	8.1e-13	29.3
WP_142499164.1\|827929_828796_+\|capsid	capsid protein	U3PDP8	Lactobacillus_phage	1.6e-97	62.5
WP_142499165.1\|828965_829391_+	hypothetical protein	NA	NA	NA	NA
WP_142499166.1\|829371_829719_+\|capsid	capsid protein	O03932	Lactobacillus_phage	1.5e-25	49.6
WP_142499167.1\|829718_830150_+	hypothetical protein	O03933	Lactobacillus_phage	1.6e-13	50.0
WP_142499168.1\|830103_830532_+\|capsid	capsid protein	NA	NA	NA	NA
WP_142499442.1\|830624_831080_+\|capsid	capsid protein	O03972	Lactobacillus_phage	1.9e-36	54.9
WP_142499169.1\|831131_831584_+	hypothetical protein	NA	NA	NA	NA
WP_142499170.1\|831586_832192_+	hypothetical protein	O03936	Lactobacillus_phage	5.3e-31	38.8
WP_142499444.1\|832381_836680_+	tape measure protein	O03937	Lactobacillus_phage	2.0e-23	32.0
834669:834684	attR	NA	NA	NA	NA
WP_142499171.1\|836679_837498_+\|tail	phage tail family protein	D2KRB8	Lactobacillus_phage	2.2e-72	49.3
WP_142499172.1\|837507_839634_+	hypothetical protein	D2KRB9	Lactobacillus_phage	1.8e-129	40.2

DBSCAN-SWA_5

889118 : 1017127

105

Streptococcus_phage(28.0%)

protease,tRNA,integrase,transposase

attL 960458:960517|attR 978851:979929

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003663813.1\|889118_889877_+\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_003675627.1\|889887_891318_+	amino acid permease	NA	NA	NA	NA
WP_003675625.1\|891440_891800_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_003675622.1\|892407_892632_-	hypothetical protein	NA	NA	NA	NA
WP_035161845.1\|892781_893114_+	DNA-binding protein	M5AWB2	Nitratiruptor_phage	3.8e-15	42.2
WP_003675618.1\|893116_893944_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	1.4e-98	63.0
WP_003675615.1\|893995_894475_-	hypothetical protein	NA	NA	NA	NA
WP_142499187.1\|894775_896152_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	2.3e-29	39.5
WP_063164563.1\|896219_897200_-	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_016496734.1\|897280_898180_+	prenyltransferase	NA	NA	NA	NA
WP_086132096.1\|898215_898917_-	bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE	NA	NA	NA	NA
WP_086132095.1\|898937_900173_-	MFS transporter	NA	NA	NA	NA
WP_003675605.1\|900291_901170_+	metallophosphoesterase family protein	NA	NA	NA	NA
WP_003667006.1\|901315_901585_+	30S ribosomal protein S14	NA	NA	NA	NA
WP_142499188.1\|901815_902508_+	hypothetical protein	NA	NA	NA	NA
WP_003675599.1\|902578_903241_+	serine dehydratase	NA	NA	NA	NA
WP_003675597.1\|903250_904132_+	L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha	NA	NA	NA	NA
WP_142499189.1\|904232_904796_+	peroxiredoxin	NA	NA	NA	NA
WP_142499190.1\|904809_906477_+	FAD-dependent oxidoreductase	A0A2I2L5E1	Orpheovirus	8.0e-53	41.7
WP_003667025.1\|908056_909460_-	C69 family dipeptidase	NA	NA	NA	NA
WP_142499191.1\|909598_911428_+	potassium transporter	NA	NA	NA	NA
WP_003663508.1\|911510_911696_+	4-oxalocrotonate tautomerase	NA	NA	NA	NA
WP_142499192.1\|911830_913333_+	glycerol kinase GlpK	NA	NA	NA	NA
WP_117115167.1\|913377_913890_+	hypothetical protein	NA	NA	NA	NA
WP_016496813.1\|913981_915358_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	3.0e-29	39.5
WP_086131836.1\|915417_915654_-	hypothetical protein	NA	NA	NA	NA
WP_142499193.1\|915663_916239_-	RNA polymerase subunit sigma-24	NA	NA	NA	NA
WP_142499194.1\|916455_916674_+	hypothetical protein	NA	NA	NA	NA
WP_035167654.1\|916789_917188_+\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	3.9e-46	62.9
WP_016496758.1\|917187_918363_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A0P0ICY9	Lactobacillus_phage	1.9e-117	55.4
WP_142499195.1\|919336_920332_+	LytR family transcriptional regulator	NA	NA	NA	NA
WP_086132580.1\|920352_921225_+	exopolysaccharide biosynthesis protein	NA	NA	NA	NA
WP_142499196.1\|921237_921981_+	polysaccharide biosynthesis tyrosine autokinase	A0A1X9I5D6	Streptococcus_phage	1.1e-22	34.7
WP_142499197.1\|922000_922930_+	NAD-dependent epimerase/dehydratase family protein	A0A1V0SKV4	Klosneuvirus	2.5e-48	37.4
WP_142499198.1\|922945_923602_+	sugar transferase	NA	NA	NA	NA
WP_142499199.1\|923601_924705_+	glycosyltransferase	L7RCM8	Acanthamoeba_polyphaga_moumouvirus	5.2e-08	22.8
WP_142499200.1\|924704_925832_+	EpsG family protein	NA	NA	NA	NA
WP_142499201.1\|925840_926350_+	serine acetyltransferase	NA	NA	NA	NA
WP_142499202.1\|926336_927572_+	oligosaccharide flippase family protein	NA	NA	NA	NA
WP_142499203.1\|927578_928577_+	glycosyltransferase	NA	NA	NA	NA
WP_142499204.1\|928573_929776_+	glycosyltransferase	NA	NA	NA	NA
WP_142499205.1\|930283_931252_+\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_142499206.1\|931953_932727_+	exopolysaccharide biosynthesis protein	NA	NA	NA	NA
WP_098039597.1\|932739_933489_+	CpsD/CapB family tyrosine-protein kinase	A0A1X9I5D6	Streptococcus_phage	3.9e-23	35.0
WP_098047036.1\|933518_934139_+	sugar transferase	NA	NA	NA	NA
WP_142499207.1\|934135_935308_+	glycosyltransferase	NA	NA	NA	NA
WP_142499446.1\|935319_936309_+	hypothetical protein	NA	NA	NA	NA
WP_142499208.1\|936317_937232_+	DUF1792 domain-containing protein	NA	NA	NA	NA
WP_072574933.1\|937231_938380_+	hypothetical protein	NA	NA	NA	NA
WP_078009533.1\|938369_939899_+	oligosaccharide flippase family protein	NA	NA	NA	NA
WP_063164027.1\|939905_940646_+	hypothetical protein	F2Y1U7	Organic_Lake_phycodnavirus	4.3e-06	24.3
WP_142499209.1\|940642_941623_+	glycosyltransferase	A0A1V0SAH6	Catovirus	5.8e-11	37.0
WP_142499210.1\|941619_942594_+	glycosyltransferase	NA	NA	NA	NA
WP_142499211.1\|942607_943726_+	glycosyltransferase	A0A1C9C5J4	Heterosigma_akashiwo_virus	6.2e-09	23.9
WP_142499212.1\|943843_945616_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_072574940.1\|945697_946738_+	acyltransferase	NA	NA	NA	NA
WP_142499213.1\|946914_951774_+	dextransucrase	NA	NA	NA	NA
WP_142499214.1\|951972_953259_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_142499215.1\|953455_954730_-\|transposase	transposase	NA	NA	NA	NA
WP_079376176.1\|954965_960293_+	dextransucrase	NA	NA	NA	NA
960458:960517	attL	NA	NA	NA	NA
WP_142499054.1\|960547_961516_+\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_003672587.1\|961601_962183_-	recombinase family protein	A0A1V0E035	Clostridioides_phage	5.3e-20	33.9
WP_086118423.1\|962301_962940_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_142499216.1\|962936_964553_-	ABC transporter permease	NA	NA	NA	NA
WP_003570727.1\|964539_965457_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	9.9e-21	27.5
WP_117115192.1\|965864_966746_+	hypothetical protein	NA	NA	NA	NA
WP_117115193.1\|966748_967336_+\|integrase	site-specific integrase	A0A141E0P1	Streptococcus_phage	3.3e-17	33.0
WP_081538463.1\|967474_968089_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_081538464.1\|968270_969188_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	1.3e-41	42.7
WP_117115194.1\|969180_969930_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_003668074.1\|969980_970949_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_142499217.1\|971041_971839_+	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
WP_003672620.1\|972008_972596_+\|integrase	site-specific integrase	A0A141E0P1	Streptococcus_phage	3.9e-18	33.5
WP_003672622.1\|972739_973102_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_056994890.1\|973104_973380_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_142499448.1\|973421_973814_+	replication protein	NA	NA	NA	NA
WP_003672437.1\|974106_976224_+	hypothetical protein	NA	NA	NA	NA
WP_003672439.1\|977059_977518_+	DUF536 domain-containing protein	NA	NA	NA	NA
WP_003672440.1\|977561_978704_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_142499054.1\|978940_979909_+\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_142499218.1\|980429_981362_+	homocysteine S-methyltransferase	NA	NA	NA	NA
978851:979929	attR	NA	NA	NA	NA
WP_016496795.1\|981354_982758_+	amino acid permease	NA	NA	NA	NA
WP_016496796.1\|982836_983094_+	hypothetical protein	NA	NA	NA	NA
WP_041816984.1\|983492_983891_+\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	3.0e-46	62.9
WP_016496797.1\|983890_985066_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A0P0ICY9	Lactobacillus_phage	5.9e-119	55.7
WP_003672329.1\|985427_985670_-	hypothetical protein	NA	NA	NA	NA
WP_142499219.1\|985851_987702_+	hypothetical protein	NA	NA	NA	NA
WP_142499220.1\|987766_991252_+	DEAD/DEAH box helicase	V9XTV7	Choristoneura_murinana_nucleopolyhedrovirus	9.0e-38	26.9
WP_003676694.1\|991347_992124_+	hypothetical protein	NA	NA	NA	NA
WP_142499221.1\|992110_992320_+	hypothetical protein	A0A0A1ERA5	Lactobacillus_phage	5.5e-12	54.5
WP_003676691.1\|992472_993591_+	exonuclease SbcCD subunit D	J9PM68	Bacillus_phage	4.2e-05	25.7
WP_142499222.1\|993592_996694_+	AAA family ATPase	NA	NA	NA	NA
WP_142499223.1\|997146_998118_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_003676686.1\|998269_998725_+	hypothetical protein	NA	NA	NA	NA
WP_016496805.1\|998753_999245_+	hypothetical protein	NA	NA	NA	NA
WP_016496806.1\|1005090_1005732_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_003673972.1\|1005874_1008181_+	glycoside hydrolase family 31 protein	NA	NA	NA	NA
WP_003673974.1\|1008338_1009598_+	chloride channel protein	NA	NA	NA	NA
WP_003668074.1\|1009638_1010607_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_035161361.1\|1010861_1011509_-	thiamine phosphate synthase	NA	NA	NA	NA
WP_086141641.1\|1011505_1012324_-	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_016496809.1\|1012316_1013126_-	hydroxyethylthiazole kinase	NA	NA	NA	NA
WP_003673979.1\|1013405_1013711_+	hypothetical protein	NA	NA	NA	NA
WP_142499224.1\|1013711_1015613_+	hypothetical protein	NA	NA	NA	NA
WP_013923736.1\|1015996_1017127_-\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	8.7e-35	32.2

DBSCAN-SWA_6

1114506 : 1171851

Staphylococcus_phage(31.25%)

holin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_142499018.1\|1114506_1115430_+\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	1.1e-32	31.0
WP_003667869.1\|1116005_1116377_-	cell division regulator GpsB	NA	NA	NA	NA
WP_003667871.1\|1116439_1117012_-	DUF1273 domain-containing protein	NA	NA	NA	NA
WP_050802151.1\|1117082_1117745_+	Holliday junction resolvase RecU	A0A1C8E9C3	Bacillus_phage	9.7e-26	36.6
WP_003674120.1\|1117756_1120021_+	PBP1A family penicillin-binding protein	NA	NA	NA	NA
WP_003674121.1\|1120098_1121016_-	DMT family transporter	NA	NA	NA	NA
WP_003666188.1\|1121038_1121743_-	DnaD domain protein	A0T2N5	Geobacillus_phage	1.5e-05	31.5
WP_003674123.1\|1121826_1122345_-	DUF5590 domain-containg protein	NA	NA	NA	NA
WP_003674125.1\|1122438_1125303_-	DEAD/DEAH box helicase	A0A1X9I5C8	Streptococcus_phage	1.9e-62	35.9
WP_016496863.1\|1125518_1126469_+	mevalonate kinase	NA	NA	NA	NA
WP_003674128.1\|1126468_1127440_+	diphosphomevalonate decarboxylase	NA	NA	NA	NA
WP_003666183.1\|1127467_1128595_+	phosphomevalonate kinase	NA	NA	NA	NA
WP_142499239.1\|1128610_1129657_+	type 2 isopentenyl-diphosphate Delta-isomerase	NA	NA	NA	NA
WP_003674130.1\|1129717_1130206_+	DUF1440 domain-containing protein	NA	NA	NA	NA
WP_142499238.1\|1130301_1131588_-\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_003674131.1\|1131771_1133961_-	alpha-galactosidase	NA	NA	NA	NA
WP_003674132.1\|1134124_1135144_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_003674133.1\|1135265_1136144_+	ROK family protein	NA	NA	NA	NA
WP_142499240.1\|1136324_1137299_-	L-lactate dehydrogenase	NA	NA	NA	NA
WP_003666171.1\|1137326_1138067_-\|holin	antiholin	NA	NA	NA	NA
WP_003666169.1\|1138059_1138479_-	CidA/LrgA family protein	NA	NA	NA	NA
WP_003674135.1\|1138680_1139412_-	response regulator	NA	NA	NA	NA
WP_142499241.1\|1139392_1141156_-	GAF domain-containing protein	Q9EYF3	Enterobacteria_phage	1.0e-58	29.8
WP_003674137.1\|1141156_1142023_-	SPFH domain-containing protein	NA	NA	NA	NA
WP_016496868.1\|1142041_1143409_-	NOL1/NOP2/sun family putative RNA methylase	NA	NA	NA	NA
WP_079376032.1\|1143553_1144366_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_003666157.1\|1144423_1144660_-	cytochrome b5	NA	NA	NA	NA
WP_142499242.1\|1145127_1145799_+	response regulator	NA	NA	NA	NA
WP_086120414.1\|1145993_1146884_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003667917.1\|1146900_1147233_-	metal-sulfur cluster assembly factor	NA	NA	NA	NA
WP_003674143.1\|1147265_1148675_-	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
WP_003674144.1\|1148667_1149129_-	SUF system NifU family Fe-S cluster assembly protein	NA	NA	NA	NA
WP_142499243.1\|1149115_1150354_-	SufS family cysteine desulfurase	Q2XUY6	environmental_halophage	1.0e-105	45.6
WP_003674148.1\|1150334_1151624_-	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
WP_003666143.1\|1151635_1152433_-	Fe-S cluster assembly ATPase SufC	A0A2R8FFL6	Cedratvirus	2.8e-11	26.4
WP_003674151.1\|1152659_1152863_+	ferrous iron transport protein A	NA	NA	NA	NA
WP_142499244.1\|1152864_1154856_+	ferrous iron transport protein B	NA	NA	NA	NA
WP_003667936.1\|1154862_1155021_+	FeoB-associated Cys-rich membrane protein	NA	NA	NA	NA
WP_142499245.1\|1155086_1156508_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	3.2e-74	34.4
WP_003667939.1\|1156522_1157344_-	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
WP_003674156.1\|1157376_1157751_+	PaaI family thioesterase	NA	NA	NA	NA
WP_003667942.1\|1158098_1158674_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_003667944.1\|1158879_1160064_-	MFS transporter	NA	NA	NA	NA
WP_086142795.1\|1160232_1163121_+	YfhO family protein	NA	NA	NA	NA
WP_086142796.1\|1163194_1163920_+	potassium channel family protein	A0A1B0Y2S3	Lactobacillus_phage	1.9e-27	45.4
WP_016496878.1\|1163965_1164424_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	7.9e-27	42.0
WP_003674164.1\|1164426_1165608_-	GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	8.1e-92	47.4
WP_086142797.1\|1165607_1166210_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.4e-31	42.5
WP_142499450.1\|1166202_1167270_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.8e-42	33.1
WP_016496813.1\|1167356_1168733_+\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	3.0e-29	39.5
WP_072575011.1\|1169094_1170039_-	pyrimidine-specific ribonucleoside hydrolase RihA	NA	NA	NA	NA
WP_142499246.1\|1170277_1171453_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A0P0ICY9	Lactobacillus_phage	8.6e-118	55.2
WP_041816984.1\|1171452_1171851_-\|transposase	IS200/IS605 family transposase	A0A286QN76	Streptococcus_phage	3.0e-46	62.9

DBSCAN-SWA_7

1178053 : 1237470

Lactobacillus_phage(47.37%)

transposase,integrase,capsid,terminase,portal,tail,head

attL 1172770:1172784|attR 1195234:1195248

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1172770:1172784	attL	NA	NA	NA	NA
WP_035157478.1\|1178053_1178989_+\|integrase	site-specific integrase	A8ATM2	Listeria_phage	1.4e-83	49.3
WP_065867984.1\|1179030_1180104_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_065867986.1\|1180280_1180574_-	HigA family addiction module antidote protein	M9MUN2	Rhodococcus_phage	5.1e-11	42.4
WP_086142405.1\|1180589_1180874_-	plasmid maintenance system killer	A0A222YWE2	Escherichia_phage	3.6e-06	40.5
WP_065867987.1\|1180945_1182130_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_086142815.1\|1182122_1183772_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	5.6e-115	46.9
WP_142499249.1\|1183784_1186895_-	HsdR family type I site-specific deoxyribonuclease	NA	NA	NA	NA
WP_142499250.1\|1187102_1187594_+	DUF805 domain-containing protein	NA	NA	NA	NA
WP_003666104.1\|1187654_1187930_-	hypothetical protein	NA	NA	NA	NA
WP_003667978.1\|1188126_1188357_+	hypothetical protein	NA	NA	NA	NA
WP_142499251.1\|1188496_1188808_+	hypothetical protein	NA	NA	NA	NA
WP_142499252.1\|1188854_1189388_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_142499253.1\|1189614_1191144_+	gluconate kinase	NA	NA	NA	NA
WP_142499254.1\|1191156_1192500_+	gluconate permease	NA	NA	NA	NA
WP_142499255.1\|1192582_1193602_+	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_142499256.1\|1193652_1195182_+	gluconate kinase	NA	NA	NA	NA
WP_142499257.1\|1195363_1195909_+	alkaline shock response membrane anchor protein AmaP	NA	NA	NA	NA
1195234:1195248	attR	NA	NA	NA	NA
WP_003666092.1\|1195923_1196115_+	hypothetical protein	NA	NA	NA	NA
WP_003674201.1\|1196132_1196516_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_016496900.1\|1196677_1197172_-	N-acetyltransferase	NA	NA	NA	NA
WP_003668066.1\|1197199_1197379_-	hypothetical protein	NA	NA	NA	NA
WP_003674203.1\|1197466_1197790_+	hypothetical protein	NA	NA	NA	NA
WP_003674205.1\|1197854_1198259_-	iron-sulfur cluster biosynthesis family protein	NA	NA	NA	NA
WP_142499258.1\|1198408_1199785_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.8e-29	39.5
WP_003674209.1\|1199857_1200793_-	manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
WP_003674211.1\|1200901_1201369_-	NUDIX hydrolase	D0R7J3	Paenibacillus_phage	8.9e-18	38.5
WP_003674213.1\|1201385_1203851_-	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	3.7e-94	31.0
WP_016496905.1\|1203869_1205879_-	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	8.6e-126	43.3
WP_003666074.1\|1206104_1206734_+	glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_079376010.1\|1206775_1207690_-	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_063164116.1\|1207787_1209908_-	type I DNA topoisomerase	A0A1V0SCS0	Indivirus	8.8e-97	36.6
WP_142499259.1\|1210404_1210650_+	hypothetical protein	NA	NA	NA	NA
WP_142499260.1\|1210753_1211143_+	hypothetical protein	NA	NA	NA	NA
WP_142499261.1\|1211165_1211660_+	hypothetical protein	NA	NA	NA	NA
WP_142499262.1\|1211703_1214250_-	hypothetical protein	NA	NA	NA	NA
WP_142499263.1\|1214823_1217358_-	hypothetical protein	NA	NA	NA	NA
WP_142499452.1\|1217375_1218569_-	LysM peptidoglycan-binding domain-containing protein	A0A0A7NU10	Lactobacillus_phage	4.4e-85	57.1
WP_142499264.1\|1218710_1219124_-	hypothetical protein	A0A0M7REJ4	Lactobacillus_phage	1.0e-04	40.3
WP_142499265.1\|1219107_1219470_-	hypothetical protein	NA	NA	NA	NA
WP_142499266.1\|1219485_1220775_-	hypothetical protein	NA	NA	NA	NA
WP_142499267.1\|1220793_1221096_-	hypothetical protein	NA	NA	NA	NA
WP_142499268.1\|1221125_1223399_-	hypothetical protein	NA	NA	NA	NA
WP_142499269.1\|1223422_1224364_-	hypothetical protein	NA	NA	NA	NA
WP_142499270.1\|1224383_1227980_-	hypothetical protein	A8YQJ9	Lactobacillus_phage	2.0e-64	36.0
WP_142499271.1\|1227999_1228272_-	hypothetical protein	NA	NA	NA	NA
WP_142499272.1\|1228243_1228624_-	hypothetical protein	NA	NA	NA	NA
WP_142499273.1\|1228723_1229329_-	hypothetical protein	NA	NA	NA	NA
WP_142499274.1\|1229347_1229725_-	DUF806 family protein	A8YQJ6	Lactobacillus_phage	1.4e-24	45.5
WP_142499275.1\|1229727_1230183_-	hypothetical protein	A0A2P0ZLE6	Lactobacillus_phage	3.3e-17	43.6
WP_142499276.1\|1230182_1230563_-\|head	phage head closure protein	A0A0M7RFE1	Lactobacillus_phage	2.5e-10	32.5
WP_142499277.1\|1230541_1230871_-\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_142499278.1\|1230896_1232834_-\|capsid	phage major capsid protein	A0A0M7RF71	Lactobacillus_phage	7.8e-116	48.9
WP_142499279.1\|1232805_1234062_-\|portal	phage portal protein	B8R650	Lactobacillus_phage	5.8e-64	37.5
WP_142499280.1\|1234086_1236021_-\|terminase	terminase large subunit	A0A0M7RDK9	Lactobacillus_phage	1.3e-147	44.2
WP_142499281.1\|1236038_1236596_-	hypothetical protein	NA	NA	NA	NA
WP_142499282.1\|1236993_1237470_-	HNH endonuclease	Q9AZM8	Lactococcus_phage	2.6e-20	36.0

DBSCAN-SWA_8

1247490 : 1343640

103

Lactobacillus_phage(48.94%)

transposase,plate,integrase,capsid,terminase,portal,protease,tail,tRNA,head

attL 1262066:1262083|attR 1327039:1327056

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_142499296.1\|1247490_1248687_+\|integrase	tyrosine-type recombinase/integrase	A0A0M9JJ77	Lactobacillus_phage	2.6e-37	29.1
WP_003674225.1\|1249647_1250418_-	ribonuclease HII	G4YAY0	Emiliania_huxleyi_virus	1.7e-21	36.1
WP_003674227.1\|1250410_1251283_-	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_003670906.1\|1251303_1251525_-	YozE family protein	NA	NA	NA	NA
WP_003674228.1\|1251543_1252146_-	YpmS family protein	NA	NA	NA	NA
WP_003674230.1\|1252148_1253075_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_142499297.1\|1253248_1254091_-	DegV family EDD domain-containing protein	A0A0N9SI50	Staphylococcus_phage	1.8e-16	34.1
WP_003666062.1\|1254269_1254914_+	hemolysin III family protein	NA	NA	NA	NA
WP_142499298.1\|1254902_1255391_-	dihydrofolate reductase	A0A1B2IBQ4	Erwinia_phage	2.1e-22	40.8
WP_003668102.1\|1255406_1256369_-	thymidylate synthase	A0A0N9SH48	Staphylococcus_phage	2.5e-115	61.2
WP_016496907.1\|1256387_1258298_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	1.8e-56	30.4
WP_003674237.1\|1258299_1259511_-\|tRNA	CCA tRNA nucleotidyltransferase	G3MAR3	Bacillus_virus	3.8e-36	39.7
WP_003674239.1\|1259636_1260902_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_003666054.1\|1261037_1261313_-	HU family DNA-binding protein	A0A0H3UZA0	Geobacillus_virus	2.6e-25	68.5
WP_003666051.1\|1261522_1262836_-	ribosome biogenesis GTPase Der	NA	NA	NA	NA
1262066:1262083	attL	NA	NA	NA	NA
WP_016496909.1\|1263065_1264316_-	30S ribosomal protein S1	NA	NA	NA	NA
WP_003674242.1\|1264388_1265075_-	(d)CMP kinase	NA	NA	NA	NA
WP_016496910.1\|1265148_1265721_-	hypothetical protein	NA	NA	NA	NA
WP_003674244.1\|1265805_1267245_-	ATP-dependent DNA helicase RecQ	F2NZ48	Diadromus_pulchellus_ascovirus	1.3e-62	39.8
WP_016496911.1\|1267234_1268260_-	hypothetical protein	NA	NA	NA	NA
WP_142499299.1\|1268360_1268939_-	ECF transporter S component	NA	NA	NA	NA
WP_003674248.1\|1269309_1270023_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_003674249.1\|1270022_1270628_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	1.5e-12	29.7
WP_003674251.1\|1270590_1271382_-	segregation/condensation protein A	NA	NA	NA	NA
WP_003674254.1\|1271374_1271731_-	hypothetical protein	NA	NA	NA	NA
WP_003674256.1\|1271744_1272638_-\|integrase	tyrosine-type recombinase/integrase	A0A0K2CP59	Brevibacillus_phage	2.5e-21	24.6
WP_003674257.1\|1272637_1273519_-	S1 RNA-binding protein	NA	NA	NA	NA
WP_003665875.1\|1273660_1275082_-	pyruvate kinase	NA	NA	NA	NA
WP_003674259.1\|1275267_1278615_-	DNA polymerase III subunit alpha	R4TB75	Streptomyces_phage	2.2e-150	33.6
WP_041821711.1\|1278697_1278943_+	YjzD family protein	NA	NA	NA	NA
WP_142499300.1\|1279402_1280566_-	hypothetical protein	A0A2R2ZGJ6	Clostridioides_phage	9.1e-11	40.2
WP_142499301.1\|1280684_1281797_-	LysM peptidoglycan-binding domain-containing protein	U3PJ04	Lactobacillus_phage	9.5e-42	43.2
WP_142499302.1\|1281798_1282206_-	hypothetical protein	A0A0A1ELI5	Lactobacillus_phage	1.5e-16	45.2
WP_142499303.1\|1282180_1282360_-	hypothetical protein	A0A0A1ENA2	Lactobacillus_phage	2.1e-07	54.9
WP_142499304.1\|1282366_1282747_-	hypothetical protein	A0A0A1ENR5	Lactobacillus_phage	8.8e-32	56.0
WP_142499305.1\|1282920_1283073_-	XkdX family protein	NA	NA	NA	NA
WP_142499306.1\|1283065_1283257_-	hypothetical protein	NA	NA	NA	NA
WP_142499307.1\|1283257_1285561_-\|plate	BppU family phage baseplate upper protein	O03968	Lactobacillus_phage	1.2e-59	51.7
WP_142499308.1\|1285560_1285878_-	hypothetical protein	NA	NA	NA	NA
WP_142499454.1\|1285894_1288414_-	peptidoglycan DD-metalloendopeptidase family protein	E9LUJ4	Lactobacillus_phage	1.2e-164	44.3
WP_142499309.1\|1288441_1289284_-\|tail	phage tail family protein	E9LUJ3	Lactobacillus_phage	3.1e-85	55.6
WP_142499310.1\|1289287_1293787_-\|tail	phage tail tape measure protein	E9LUJ2	Lactobacillus_phage	4.4e-271	60.5
WP_003670997.1\|1293982_1294324_-	hypothetical protein	E9LUJ0	Lactobacillus_phage	6.1e-16	42.1
WP_142499311.1\|1294376_1295006_-\|tail	phage tail protein	E9LUI9	Lactobacillus_phage	1.5e-76	72.9
WP_142499312.1\|1295005_1295425_-	hypothetical protein	D2KRB3	Lactobacillus_phage	2.8e-39	52.9
WP_003663710.1\|1295421_1295796_-	HK97 gp10 family phage protein	E9LUI7	Lactobacillus_phage	5.8e-36	63.2
WP_142499313.1\|1295779_1296133_-\|head	phage head closure protein	E9LUI6	Lactobacillus_phage	2.2e-37	64.9
WP_142499314.1\|1296035_1296449_-\|head,tail	phage gp6-like head-tail connector protein	E9LUI5	Lactobacillus_phage	2.4e-30	63.8
WP_142499315.1\|1296590_1297730_-\|capsid	phage major capsid protein	D2KRA9	Lactobacillus_phage	1.1e-146	73.7
WP_142499316.1\|1297730_1298384_-\|head,protease	HK97 family phage prohead protease	D2KRA8	Lactobacillus_phage	2.4e-61	70.3
WP_142499317.1\|1298322_1299582_-\|portal	phage portal protein	D2KRA7	Lactobacillus_phage	3.0e-177	75.5
WP_086131867.1\|1299588_1299744_-	DUF1056 family protein	NA	NA	NA	NA
WP_142499318.1\|1299910_1300132_-	hypothetical protein	NA	NA	NA	NA
WP_142499319.1\|1300112_1301822_-\|terminase	terminase large subunit	E9LUI0	Lactobacillus_phage	9.7e-288	83.7
WP_085680634.1\|1301818_1302286_-\|terminase	phage terminase small subunit P27 family	E9LUH9	Lactobacillus_phage	9.1e-47	65.4
WP_142499320.1\|1302469_1303264_-	AAA family ATPase	E9LUN5	Lactobacillus_phage	3.6e-112	71.9
WP_142499456.1\|1303931_1304477_-	hypothetical protein	A0A191KBR1	Streptococcus_virus	1.4e-06	29.5
WP_142499321.1\|1304491_1305415_-	DUF4868 domain-containing protein	NA	NA	NA	NA
WP_142499322.1\|1306242_1306758_-	hypothetical protein	NA	NA	NA	NA
WP_142499323.1\|1307011_1307317_-	hypothetical protein	NA	NA	NA	NA
WP_085681283.1\|1307309_1307528_-	hypothetical protein	NA	NA	NA	NA
WP_066035353.1\|1307663_1307846_-	hypothetical protein	NA	NA	NA	NA
WP_099979603.1\|1307845_1308592_-	hypothetical protein	A0A1L2JZ42	Aeribacillus_phage	1.9e-38	42.9
WP_142499324.1\|1308595_1309021_-	replication terminator protein	M1I9V9	Streptococcus_phage	6.2e-26	50.0
WP_085681297.1\|1309013_1309361_-	hypothetical protein	NA	NA	NA	NA
WP_142499325.1\|1309370_1309835_-	HNH endonuclease	X2KPF7	Streptococcus_phage	1.9e-12	32.4
WP_085649873.1\|1309806_1310067_-	hypothetical protein	NA	NA	NA	NA
WP_085681277.1\|1310056_1310533_-	hypothetical protein	NA	NA	NA	NA
WP_142499326.1\|1310532_1311558_-\|integrase	tyrosine-type recombinase/integrase	A8ATD6	Listeria_phage	6.0e-59	40.2
WP_142499327.1\|1311448_1312069_-	N-6 DNA methylase	A0A097BYG1	Leuconostoc_phage	9.3e-55	48.3
WP_142499328.1\|1312073_1312979_-	hypothetical protein	L0P704	Lactobacillus_phage	2.2e-36	61.6
WP_085680981.1\|1312990_1313200_-	hypothetical protein	NA	NA	NA	NA
WP_085678363.1\|1313233_1313422_-	hypothetical protein	NA	NA	NA	NA
WP_142499329.1\|1313562_1313802_-	hypothetical protein	NA	NA	NA	NA
WP_142499330.1\|1313969_1314425_+	hypothetical protein	NA	NA	NA	NA
WP_003663758.1\|1314636_1314867_-	transcriptional regulator	NA	NA	NA	NA
WP_142499331.1\|1315002_1315665_+	helix-turn-helix domain-containing protein	U3PIS7	Lactobacillus_phage	1.9e-45	45.1
WP_142499332.1\|1315723_1316362_+	hypothetical protein	NA	NA	NA	NA
WP_142499333.1\|1316381_1316963_+	hypothetical protein	NA	NA	NA	NA
WP_109913733.1\|1317343_1317556_-	hypothetical protein	NA	NA	NA	NA
WP_142499334.1\|1317566_1317770_-	hypothetical protein	NA	NA	NA	NA
WP_142499335.1\|1317833_1318616_+	hypothetical protein	NA	NA	NA	NA
WP_099979621.1\|1318779_1319892_+\|integrase	site-specific integrase	A0A1P8BMN3	Lactococcus_phage	3.6e-57	37.1
WP_003674261.1\|1319928_1321179_-	peptidase T	NA	NA	NA	NA
WP_142499336.1\|1321203_1322028_-	Nif3-like dinuclear metal center hexameric protein	NA	NA	NA	NA
WP_079376002.1\|1322014_1322731_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_003674266.1\|1322819_1324004_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_016496838.1\|1324243_1325530_-\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_003674268.1\|1325720_1326863_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	2.5e-37	36.6
WP_016496915.1\|1326864_1328730_-	DNA primase	I6P4U6	Helicobacter_phage	1.0e-48	34.2
1327039:1327056	attR	NA	NA	NA	NA
WP_016496916.1\|1328864_1330940_-\|tRNA	glycine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_003665860.1\|1330941_1331928_-\|tRNA	glycine--tRNA ligase subunit alpha	NA	NA	NA	NA
WP_003674276.1\|1332188_1332974_-	DNA repair protein RecO	NA	NA	NA	NA
WP_003674278.1\|1332989_1333895_-	GTPase Era	NA	NA	NA	NA
WP_142499337.1\|1333906_1334302_-	diacylglycerol kinase family protein	NA	NA	NA	NA
WP_003665856.1\|1334285_1334765_-	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_003674280.1\|1334764_1335772_-	PhoH family protein	H6X2N1	Pseudomonas_phage	8.6e-50	48.4
WP_016496918.1\|1335871_1336843_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_016496919.1\|1336848_1337421_-	biotin transporter BioY	NA	NA	NA	NA
WP_072575053.1\|1337548_1338934_-	argininosuccinate lyase	NA	NA	NA	NA
WP_003674287.1\|1340314_1341292_-	choloylglycine hydrolase family protein	A0A2K9L5Y5	Tupanvirus	1.4e-17	24.8
WP_142499338.1\|1341359_1342328_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_013923736.1\|1342509_1343640_+\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	8.7e-35	32.2

DBSCAN-SWA_9

1675181 : 1751470

Streptococcus_phage(35.29%)

holin,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_142499359.1\|1675181_1675640_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_142499360.1\|1675759_1676734_-	phosphate acetyltransferase	NA	NA	NA	NA
WP_003676241.1\|1676794_1677484_-	uracil-DNA glycosylase	A0A0A8IL23	Epstein-Barr_virus	1.0e-41	49.2
WP_003667483.1\|1677634_1678219_+	hypothetical protein	NA	NA	NA	NA
WP_003666449.1\|1678275_1678749_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	4.0e-42	54.8
WP_142499361.1\|1678766_1681172_-	ribonuclease R	Q0GXV6	Lactococcus_phage	7.7e-89	38.3
WP_142499362.1\|1681158_1681935_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_003676245.1\|1682013_1682238_-	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_086132300.1\|1682319_1683870_-	ClC family H(+)/Cl(-) exchange transporter	NA	NA	NA	NA
WP_003666444.1\|1683987_1685370_-	amino acid permease	NA	NA	NA	NA
WP_003666443.1\|1685565_1686888_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	8.9e-172	69.9
WP_003667474.1\|1686978_1687728_-	triose-phosphate isomerase	NA	NA	NA	NA
WP_063164244.1\|1687843_1689049_-	phosphoglycerate kinase	NA	NA	NA	NA
WP_003666436.1\|1689139_1690147_-	type I glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_003666435.1\|1690649_1691243_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	8.0e-56	54.3
WP_003666428.1\|1692180_1693122_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	1.2e-50	38.4
WP_003667464.1\|1693140_1694127_-	uridine diphosphate-N-acetylglucosamine-binding protein YvcK	A1IMD5	Streptococcus_phage	1.9e-94	55.2
WP_142499363.1\|1694142_1695036_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	4.5e-10	29.4
WP_012390508.1\|1695122_1696454_-	amino acid permease	NA	NA	NA	NA
WP_003667458.1\|1696722_1699587_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	4.0e-310	55.9
WP_142499364.1\|1699602_1701618_-	excinuclease ABC subunit UvrB	NA	NA	NA	NA
WP_003666419.1\|1701839_1702112_-	hypothetical protein	NA	NA	NA	NA
WP_003666416.1\|1702216_1702855_-	HD domain-containing protein	NA	NA	NA	NA
WP_003667456.1\|1703021_1704746_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	5.0e-199	59.8
WP_003667454.1\|1704835_1705342_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_003667453.1\|1705387_1706272_-	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_109883758.1\|1706530_1707700_-	ArgE/DapE family deacylase	NA	NA	NA	NA
WP_109883756.1\|1707794_1708727_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	1.7e-84	51.8
WP_003667448.1\|1708923_1709793_+	(Fe-S)-binding protein	NA	NA	NA	NA
WP_109897249.1\|1709793_1711281_+	iron-sulfur cluster-binding protein	NA	NA	NA	NA
WP_003667445.1\|1711273_1712008_+	lactate utilization protein C	NA	NA	NA	NA
WP_003666398.1\|1712074_1712989_-	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	7.5e-69	46.4
WP_142499365.1\|1713053_1714070_-	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_142499366.1\|1714095_1714923_-	prolipoprotein diacylglyceryl transferase	NA	NA	NA	NA
WP_086118063.1\|1714915_1715887_-	HPr kinase/phosphorylase	NA	NA	NA	NA
WP_003670462.1\|1715900_1716257_-\|holin	phage holin family protein	NA	NA	NA	NA
WP_142499367.1\|1716256_1716592_-	PspC domain-containing protein	NA	NA	NA	NA
WP_102816417.1\|1716621_1717620_-	peptide chain release factor 2	NA	NA	NA	NA
WP_102816418.1\|1717663_1717819_-	acyl dehydratase	NA	NA	NA	NA
WP_142499368.1\|1717819_1720183_-	preprotein translocase subunit SecA	NA	NA	NA	NA
WP_003667436.1\|1720389_1720938_-	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_142499369.1\|1721730_1723062_-	DEAD/DEAH box helicase family protein	A0A1X9I5S6	Streptococcus_phage	1.6e-75	38.2
WP_142499370.1\|1723123_1723756_+	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	2.1e-38	41.5
WP_142499371.1\|1725164_1739780_-	hypothetical protein	NA	NA	NA	NA
WP_142499457.1\|1739915_1740962_-\|transposase	IS30 family transposase	H7BW47	unidentified_phage	1.6e-27	34.0
WP_142499372.1\|1741111_1742827_+\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	1.0e-95	39.3
WP_142499373.1\|1743124_1743583_+\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	3.9e-18	36.3
WP_142499374.1\|1743817_1745317_-	glycosyltransferase	NA	NA	NA	NA
WP_142499375.1\|1745317_1746874_-	glycosyltransferase	NA	NA	NA	NA
WP_003668074.1\|1747853_1748822_+\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_003667431.1\|1749634_1750045_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_072575358.1\|1750183_1751470_-\|transposase	ISL3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_10

1962158 : 2030354

unidentified_phage(13.33%)

protease,tRNA,integrase,transposase

attL 1966385:1966404|attR 1990211:1990230

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_016497152.1\|1962158_1962893_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_003674515.1\|1962968_1963673_-	hypothetical protein	NA	NA	NA	NA
WP_003667139.1\|1963782_1964103_-	membrane protein	NA	NA	NA	NA
WP_063164286.1\|1964389_1965745_+	FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	3.7e-125	52.0
WP_003667137.1\|1965871_1966159_-	hypothetical protein	NA	NA	NA	NA
WP_013923736.1\|1966296_1967427_+\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	8.7e-35	32.2
1966385:1966404	attL	NA	NA	NA	NA
WP_086143147.1\|1967512_1970362_-	DEAD/DEAH box helicase	A0A0A1ENT0	Lactobacillus_phage	3.3e-22	26.8
WP_142499411.1\|1970382_1970883_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_086132026.1\|1970882_1971836_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.1e-14	23.8
WP_085719611.1\|1972090_1974313_+	alpha-galactosidase	NA	NA	NA	NA
WP_085719612.1\|1974328_1974955_+	Tat pathway signal sequence	NA	NA	NA	NA
WP_085719613.1\|1974997_1975825_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_003665466.1\|1976049_1976820_-	triose-phosphate isomerase	NA	NA	NA	NA
WP_003665465.1\|1976951_1977353_+	phosphate-starvation-inducible protein PsiE	NA	NA	NA	NA
WP_003674501.1\|1977364_1977907_+	serine hydrolase family protein	NA	NA	NA	NA
WP_003674500.1\|1979880_1981299_+	sodium:proton antiporter	NA	NA	NA	NA
WP_003665459.1\|1981444_1981678_+	cytochrome b5	NA	NA	NA	NA
WP_003674496.1\|1981743_1982394_-	NAD(P)H-binding protein	NA	NA	NA	NA
WP_142499413.1\|1982472_1982700_-	hypothetical protein	NA	NA	NA	NA
WP_142499415.1\|1982807_1983548_+	SDR family oxidoreductase	W8CYX9	Bacillus_phage	3.5e-08	38.2
WP_142499417.1\|1983711_1985034_-	MFS transporter	NA	NA	NA	NA
WP_003674489.1\|1985758_1986328_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_063164289.1\|1986469_1987330_+\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_003674487.1\|1987521_1987746_+	hypothetical protein	NA	NA	NA	NA
WP_003674484.1\|1987866_1988355_+	cyclic pyranopterin monophosphate synthase MoaC	NA	NA	NA	NA
WP_003674482.1\|1988405_1988744_-	metal-sulfur cluster assembly factor	NA	NA	NA	NA
WP_003674480.1\|1988746_1989745_-	GTP 3',8-cyclase MoaA	NA	NA	NA	NA
WP_013923736.1\|1990122_1991253_+\|transposase	IS30 family transposase	H7BVY4	unidentified_phage	8.7e-35	32.2
1990211:1990230	attR	NA	NA	NA	NA
WP_016497165.1\|1997138_1998389_-\|tRNA	tyrosine--tRNA ligase	K4F5T3	Cronobacter_phage	7.8e-85	41.5
WP_003675881.1\|1998912_1999962_-	hypothetical protein	NA	NA	NA	NA
WP_003665449.1\|2000129_2000816_-	2,3-diphosphoglycerate-dependent phosphoglycerate mutase	NA	NA	NA	NA
WP_003675884.1\|2000911_2002171_-	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_003675891.1\|2004310_2005348_-	phosphoribosylformylglycinamidine cyclo-ligase	M4QRQ6	Synechococcus_phage	1.1e-60	39.9
WP_003675893.1\|2005352_2006807_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.4e-56	32.7
WP_003675894.1\|2006782_2009011_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.3e-148	41.8
WP_003675896.1\|2009014_2009695_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_003675897.1\|2009695_2009944_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_063164290.1\|2009944_2010664_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	NA	NA	NA	NA
WP_003675901.1\|2010886_2012182_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	9.4e-17	31.3
WP_035161928.1\|2012253_2013408_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_016497168.1\|2013370_2013856_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.8e-21	44.4
WP_003675907.1\|2014037_2014754_-	acetolactate decarboxylase	NA	NA	NA	NA
WP_003675908.1\|2014770_2016450_-	acetolactate synthase AlsS	G8DDL3	Micromonas_pusilla_virus	8.7e-31	22.9
WP_003675909.1\|2016634_2018296_-	formate--tetrahydrofolate ligase	NA	NA	NA	NA
WP_003665417.1\|2018464_2019508_-	AI-2E family transporter	NA	NA	NA	NA
WP_003675910.1\|2019679_2020855_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_003675911.1\|2021112_2021775_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.8e-40	46.0
WP_086120158.1\|2021833_2022493_+	HAD hydrolase-like protein	NA	NA	NA	NA
WP_016497172.1\|2022564_2023206_-	orotate phosphoribosyltransferase	NA	NA	NA	NA
WP_142499419.1\|2023202_2023949_-	orotidine-5'-phosphate decarboxylase	NA	NA	NA	NA
WP_003665409.1\|2023930_2024857_-	dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_003665407.1\|2024856_2026149_-	dihydroorotase	NA	NA	NA	NA
WP_003675915.1\|2026162_2027092_-	aspartate carbamoyltransferase catalytic subunit	A0A1J0F9B8	Only_Syngen_Nebraska_virus	5.0e-28	36.9
WP_035161933.1\|2027436_2028318_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_013924000.1\|2028935_2030354_+\|transposase	ISLre2-like element ISLre2 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP030090

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP030089

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection