CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP041187	Pseudarthrobacter sp. NIBRBAC000502771 chromosome, complete genome	1 crisprs	csa3,cas3,DEDDh,WYL,DinG,RT	0	0	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP041187_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP041187_1

4307565-4307769

Orphan

Consensus_repeat	Method
CAACCACCGACCCCGCAACCAACGGCACCACCGACCTGACCGCCGCAGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP041187_1

>merge|NZ_CP041187|1|4307565-4307769|CRISPRCasFinder
CCGCCACTGATCCCGCTACCACCGGCGCCACCGACCTGGCAGCCGCAGCGGACGTCAACCTGGGGCTGGGGGCTGTGGCTGCCACAGATCCCGCAACCAACGGCACCACCGACCTAACCGCCGCAGCCGACGTCAATCTCGGACTCGGCAACGTCGCAACCACCGACCCCGCAACCAACGGCACCACCGACCTGACCGCCGCAGC

>NZ_CP041187|1|1|4307565-4307769|CRISPRCasFinder
CCGCCACTGATCCCGCTACCACCGGCGCCACCGACCTGGCAGCCGCAGC	GGACGTCAACCTGGGGCTGGGGGCTGTGGCTGCCACAGATCCCGCAACCAACGGCACCACCGACCTAACCGCCGCAGCCGACGTCAATCTCGGACTCGGCAACGTCG
CAACCACCGACCCCGCAACCAACGGCACCACCGACCTGACCGCCGCAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP041187.1\|WP_141161245.1\|4318196_4318628_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041187.1\|WP_141161234.1\|4302760_4304200_+\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|226957
NZ_CP041187.1\|WP_141161240.1\|4309905_4310415_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235401
NZ_CP041187.1\|WP_141161232.1\|4298528_4300088_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224053
NZ_CP041187.1\|WP_168225762.1\|4314010_4314181_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041187.1\|WP_141161237.1\|4306300_4307230_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236766
NZ_CP041187.1\|WP_141161231.1\|4297206_4298397_+\|ROK-family-protein	unknown	unknown	gnl\|CDD\|224851
NZ_CP041187.1\|WP_141161233.1\|4301466_4302561_+\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|380649
NZ_CP041187.1\|WP_141161242.1\|4314257_4315943_-\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
NZ_CP041187.1\|WP_141161235.1\|4304202_4304910_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224059
NZ_CP041187.1\|WP_141161236.1\|4305029_4306100_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_CP041187.1\|WP_141161230.1\|4296120_4296978_-\|nitrilase	unknown	unknown	gnl\|CDD\|143600
NZ_CP041187.1\|WP_141161239.1\|4308700_4309909_+\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP041187.1\|WP_018761952.1\|4300133_4301417_+\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226669
NZ_CP041187.1\|WP_141161246.1\|4318641_4319958_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP041187.1\|WP_141161244.1\|4317575_4318157_-\|phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|235544
NZ_CP041187.1\|WP_141161247.1\|4320397_4321240_-\|DUF2382-domain-containing-protein	unknown	unknown	gnl\|CDD\|378207
NZ_CP041187.1\|WP_141161241.1\|4313058_4314027_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226119
NZ_CP041187.1\|WP_141161229.1\|4294508_4296113_+\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|377939
NZ_CP041187.1\|WP_141161243.1\|4316086_4317439_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|273327

Protein	Function_ID	Function_description	E-value
NZ_CP041187.1\|WP_141161234.1\|4302760_4304200_+\|FtsX-like-permease-family-protein	gnl\|CDD\|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	5.95253e-22
NZ_CP041187.1\|WP_141161240.1\|4309905_4310415_+\|hypothetical-protein	gnl\|CDD\|235401	PRK05306, infB, translation initiation factor IF-2; Validated.	7.68582e-05
NZ_CP041187.1\|WP_141161232.1\|4298528_4300088_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
NZ_CP041187.1\|WP_141161237.1\|4306300_4307230_+\|hypothetical-protein	gnl\|CDD\|236766	PRK10811, rne, ribonuclease E; Reviewed.	0.000101404
NZ_CP041187.1\|WP_141161231.1\|4297206_4298397_+\|ROK-family-protein	gnl\|CDD\|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	1.09274e-61
NZ_CP041187.1\|WP_141161233.1\|4301466_4302561_+\|substrate-binding-domain-containing-protein	gnl\|CDD\|380649	cd19994, PBP1_ChvE, periplasmic sugar binding protein ChvE that interacts with a bacterial two-component signaling system. Periplasmic aldose-monosaccharides binding protein ChvE that belongs to a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes a transition from an open to a closed conformational state upon ligand binding. Moreover, the periplasmic xylose-binding protein is homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR.	4.0253e-148
NZ_CP041187.1\|WP_141161242.1\|4314257_4315943_-\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NZ_CP041187.1\|WP_141161235.1\|4304202_4304910_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	6.0314e-108
NZ_CP041187.1\|WP_141161236.1\|4305029_4306100_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.8833e-56
NZ_CP041187.1\|WP_141161230.1\|4296120_4296978_-\|nitrilase	gnl\|CDD\|143600	cd07576, R-amidase_like, Pseudomonas sp. MCI3434 R-amidase and related proteins (putative class 13 nitrilases). Pseudomonas sp. MCI3434 R-amidase hydrolyzes (R,S)-piperazine-2-tert-butylcarboxamide to form (R)-piperazine-2-carboxylic acid. It does so with strict R-stereoselectively. Its preferred substrates are carboxamide compounds which have the amino or imino group connected to their beta- or gamma-carbon. This subgroup belongs to a larger nitrilase superfamily comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13), class 13 represents proteins that at the time were difficult to place in a distinct similarity group. It has been suggested that this subgroup represents a new class. Members of the nitrilase superfamily generally form homomeric complexes, the basic building block of which is a homodimer. Native R-amidase however appears to be a monomer.	9.70241e-92
NZ_CP041187.1\|WP_141161239.1\|4308700_4309909_+\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.12541e-87
NZ_CP041187.1\|WP_018761952.1\|4300133_4301417_+\|sugar-ABC-transporter-permease	gnl\|CDD\|226669	COG4214, XylH, ABC-type xylose transport system, permease component [Carbohydrate transport and metabolism].	3.84133e-119
NZ_CP041187.1\|WP_141161244.1\|4317575_4318157_-\|phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|235544	PRK05647, purN, phosphoribosylglycinamide formyltransferase; Reviewed.	1.34647e-105
NZ_CP041187.1\|WP_141161247.1\|4320397_4321240_-\|DUF2382-domain-containing-protein	gnl\|CDD\|378207	pfam09557, DUF2382, Domain of unknown function (DUF2382). This entry describes an uncharacterized domain, sometimes found in association with a PRC-barrel domain pfam05239 which is also found in rRNA processing protein RimM and in a photosynthetic reaction centre complex protein). This domain is found in proteins from Bacillus subtilis, Deinococcus radiodurans, Nostoc sp. PCC 7120, Myxococcus xanthus, and several other species. The function is not known.	1.22141e-33
NZ_CP041187.1\|WP_141161241.1\|4313058_4314027_+\|hypothetical-protein	gnl\|CDD\|226119	COG3591, COG3591, V8-like Glu-specific endopeptidase [Amino acid transport and metabolism].	2.0012e-06
NZ_CP041187.1\|WP_141161229.1\|4294508_4296113_+\|PucR-family-transcriptional-regulator	gnl\|CDD\|377939	pfam07905, PucR, Purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being putative regulatory proteins.	2.44461e-21
NZ_CP041187.1\|WP_141161243.1\|4316086_4317439_+\|MFS-transporter	gnl\|CDD\|273327	TIGR00895, transport_protein, benzoate transport. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	7.86158e-63

>NZ_CP041187.1|WP_141161237.1|4306300_4307230_+|hypothetical-protein
MARSSSPWRALRPVLLSGAAAATWLTLSSTPATADTGPDSSSPLGAPTSSVSSVGQDLAARVSPIPAGSADGPAASPGLLQPVITPVSGLTDNLIAAVPVVDQVVPAGTVSGVSAPLVEVADTLAAGVARELTAPAAEALPVLEPVLQPVSDLLNGAVSLPAPPLDDVKVDVPGVLAPAPAGDLPSAVEEAPDATDTATESGQAVEAPSTASDAGIPANMAFPQAGVFETLGSIAEQPLAVDPLPVPAQAPAAPAPGTGSSGSSGGTSAAAAWLNPIYFDFEGAGAVRADRSPGHVPSPVSFDPGSSPD
>NZ_CP041187.1|WP_141161236.1|4305029_4306100_+|Gfo/Idh/MocA-family-oxidoreductase
MSAPIATPWLSTQPDRDPRTATGTPLRWGIIATGSIARAVSQDLALLEDAELYAVSSRAQDTADAFAVAYDFAKAYGDDGGVPGYQRLLADDAVDVVYVATPHAQHHGMVLAALNAGKHVLCEKTFTINAREAAELIEVARSRKLFLMEAVWSRFLPSMQRAFEIAASGELGDIHWVTADLGFPAPYSPTARLWARKDGGGALLDLSVYPLLWALGTLGFPQTVSATGFVNDDGVDAQNALSLGYGHAAQVQLTSSLLAHGPRTATVAGSLGFLQSVGSINNPRELVIAKGWEDRRTESFDVVGKGYAYELREVMRCVQQGLSESPVMPLEDTLNTMRLFDGVRAQLGVTYPNDSR
>NZ_CP041187.1|WP_141161235.1|4304202_4304910_+|ATP-binding-cassette-domain-containing-protein
MIEVKNLVRTFNSGDRTIKPVNDVSFVLEQGTLASIVGKSGSGKSTLLSLLGALDKPTSGDVVVNGVSLANLPDSKLTEYRRRDSGFVFQQFNLIPNLSAVDNVMLPMEFAGKRKSDRLERAKGLLEQVQLDPSKHDRRINRLSGGEQQRVAIARALANEPKLILADEPTGNLDEQTGDHIIELLSSLSRDHNTTILVVTHDRVLANKTDRRFRLQQGKLTEEPVRGRTAVAASA
>NZ_CP041187.1|WP_141161234.1|4302760_4304200_+|FtsX-like-permease-family-protein
MSVLARSVGNAFRNKVRTAAVVAVLAVAIGLALAMLVANQAVGAKVQELNASVGTVLTVNPAGGQGFEGGGEPLTADQAATAAGVPNVSAVVGTSSLRLRNADAAAAQAAAGGTGQAGPGGQTGQGGPGGQAAATLTTSLTAAVDAGTLGNRNQQANGTTGSTGTTQQPVRSLPITATGIGAEVDTTGKALNITQGTGLGDYSAASTGALLGTTLAEKNGLSVGSSFTINDQAYTVTGLFDAGTAFGNNAVYVTLPTAQTLAGTPGELSSMIVTVNSMDNVATAKAALQAALGTGKADVTQGQNLQTAVSSLDSVKNISFIAFVAALGTAGLIILLIMVMLVRERRREIGVLKAIGAPNRTIGLQFVLEALVLAALGSAVGAAIASFASGGIASALISSNSTATAGRNFPAAAGGVSVRGTQGGPFGGASQLLNSVTASASPEVIAGGIAAVFGVAIIGALIPALLTARIRPIEVLRGE
>NZ_CP041187.1|WP_141161233.1|4301466_4302561_+|substrate-binding-domain-containing-protein
MRMFGKAGKAAAVAAIAALALTGCGRSEPSGGSSSGAAGFDQNSSIGVALPQKTSENWVLAEKLFNDGLNGAGFKADVQFANGGVSEQQNQISAMVTKGAKVIIVGAIDGSQLGTQLKQAKDAGATIIAYDRLLLNTANVDYYVAYDNFKVGVLQGQALLDGLKAKKPAGPYNIELFAGSPDDANAKVFFNGAMSVLKPKIDDGTLKVVSGQNSFEQAVTQGWKAENAQRRMDTLLSGSYTTANVDGVLSPNDTLARAILTSVKAAGKPIPVVTGQDSEVESVKSIMAGEQYSTINKDTRKLVEHAITMVKDLQAGKKPEVNDDKSYNNGNKVVPAYLLEPVIVTSANVKTAYTDDPVLGPITK
>NZ_CP041187.1|WP_018761952.1|4300133_4301417_+|sugar-ABC-transporter-permease
MNALKKLFGGNTRQFGMIFALVALIIFFQIFTDGRTLTPGNVINLFNGNSYILILAIGMVLVIIAGHIDLSVGSVAAFVGVSVALAIRDWGIPWYAGVLLGLLLGALIGAWQGLWTAYVGIPAFIVTLAGMLLFRGFNQFVGKSNTIPVPEDFQYLGSGYLPEVGPDTGFNNLTLLMGIAVAVFVVVGELRARARAKALGAGVPEMWVTVVKLVLICAAILYATYLFATGRPGTSFPIPGLILAVLVLIYGFISSRTVVGRHVYAVGGNRHAAELSGVQSKKVNFLVMMNMSILAGLAGMIFVGRSTASGPFDGVGWELDAIAAVFIGGAAVTGGVGTVVGSIIGGLVMAVLNNGLQLLGVGADLTQIIKGLVLLIAVAFDVYNKSQGKRSIIGMLTRNMNRNTAGPSGPIQPDETTSTKEAIAREA
>NZ_CP041187.1|WP_141161232.1|4298528_4300088_+|ATP-binding-cassette-domain-containing-protein
MTSQTTHADPVILEMRSITKEFPGVKALSNVSLRVKAGEIHAICGENGAGKSTLMKVLSGVYPYGSYDGDIVYQGQVQQFRDIRASEHAGIVIIHQELALIPELSIMENIFLGNEPTKRGIIDWAEARLRSLDLLARVGLRDDPDTPIKEIGVGKQQLVEIAKALNKSVKILILDEPTAALNESDSQHLLDLMLGLKAKGITSIIISHKLNEIEQVADSITIIRDGKSIETLDVKKDGVDEDRIIKGMVGRTLESRFPDHTPKIGEVFFEVKDWTVGHPAIQDRLVCKGSNFFVRRGEIVGFAGLMGAGRTELARSVFGRSYGRFIDGHIYKDGKEVVLKSVRHAIDAGLGYVTEDRKSLGLNLLDDIKTTTVAANLRKISHNFVVDANQEFTVAEQYRKSLRTKTPSVEEGVAKLSGGNQQKVVLAKWMFTDPDLLILDEPTRGIDVGAKYEIYGIIQQLANQGKGVIVISSELPELLGLSDRIYTIFEGAITGVLNKDEASQESLMKLMTSATRKAA
>NZ_CP041187.1|WP_141161231.1|4297206_4298397_+|ROK-family-protein
MSATTRSTRSKPKNPGSQSALRQQNQQRIIETLMGGPSTQAELARQTGLSTATVSNIVRIMLDSGLASTEPITSSGRRALNVRLNSNGAVAVGIDFGRRHLRVVLASLSYHVIAEESVMLPLGHQADDGIQAAVSLLEKLLRESGVERTSVVGAGVGIPGPIDRRTGTVAQGAILPEWVGINILQHLEETLRIPVFVDNDANLGAWSEVTWGQHSGVSNLMFLKIGSGIGAGLILNGAPYYGNVGITGEIGHATIHEQGLVCRCGNRGCLETIASTTTMIELLSRGEDRPMTPADIVRKALNRDSATLRVVDDAGLAVGRALGNVANLINPEVIVVGGPLAGLGDILLDPIRRGLVRHAVPVIGETTTLAMSSLGDRAEALGAAALVFQHAGIRKP
>NZ_CP041187.1|WP_141161230.1|4296120_4296978_-|nitrilase
MLLSVLQANAVVLDIEANLRTVDQAARQAAQAGAHLLLTPELFPVGYAPLRLRRDLDPAAIPAVRERLAGIARSTGVALVYSLPAPAGGETESAGGTGWHISATLVDAGGREILTYAKVHLFGDEERRAFVPASQPPAVVDFHGIRTSLLICYDIEFPEAALEAAARGAELVLVPTALSAGFEAVPQVLIRARALESQLHVAYANHCGSEDAYIFGGGSVVAGPDGALLAEAADGQALLFAEVGAEAVRAAREVVPYLRERRPGVYREWEADRPQERGLPGNGRP
>NZ_CP041187.1|WP_141161229.1|4294508_4296113_+|PucR-family-transcriptional-regulator
MTVEPGESGPLSFVTLQQFLDQLPPLLKLLHDGGSGGRLLRWVEPSELEDPTPYLPEGEFLLTAGLPFLGGGGTPARVDAYVRRLVQAKVAALGFGIRPYFDAVPDVVVEACRRHNLTLFEVPESLPFAAIGLQFSQLLETDNARVFRQLAETNRQLMRAVLSPRPEHELLAALVQRVPVWAVLVGADGRVRARGTSDGGSTAVDLSLLEPMLDRLLSGRGPRVEMDGFDQPGSALVVGHPLRSTKDANLGALILGSDAPLTPAQNNVVQSAVGLLELLVRQRTSGSLAPSQLATAVLLHPESLAAGSTRHLNGLKDLLAQSLSSTRSAPMRVVQGINVEAPQWPAGDGPVRELLQWRRMLDTKLVEVTDYGFAAVTRLRVDDALLADVERLGWRLVIGEPTELTGLSAAYQRATSLRSQVQRSGRSVRADEVSWSVTGLLGREAGTLLAERLLQPVLALEPDRRHPLLAVLRGWLSENGSWDASAKLLGLHRNSVRRQIGVLGELLQMDLNQAQVRAELWIALQYADGVAGAD
>NZ_CP041187.1|WP_141161239.1|4308700_4309909_+|protein-kinase
MVAESPSSIKNEVVGGRYRLGEVVGRGGMSSVYCARDENLGRDVALKLFAPQAPDADELKRQEAEIQLLATLNHPGLVTLFDAGIDDRIPDEPRPFLTMELVEGQDLRSRIRHSTVPLEELAVIGAGIADALAYVHGLGIIHRDIKPGNILLVQIRPGEPIRPKLTDFGIARIVDSTRLTATGTMVGTAAYLSPEQALGKPLSSATDIYSLGLVLLECIKGTVEYPGSAVESAVARLHRAPEIPDDVPSEWAGLIRSMTAIEPLERPAAADIETVLRQALVSPASTPGELAPETTRVLPAMPFHPPSITAEESVEDVREAAAAPRTTDPAPGTEAGTSAAKPRLTRSRRIWLAVVVGVLVVAAAAAAVLMSISARPADVVPYPTVTGVLGDHLQELQKSVAP
>NZ_CP041187.1|WP_141161240.1|4309905_4310415_+|hypothetical-protein
MILRQAPAGRLLLACAAAALAAALLSACAAPGAGLQREAATQLQARVLEVTQASSQNDPAAALKALEGLEADLSAAQAKGQVSEERRRSITTVATAVRADLNEAISAQAAAAKAAEDARIAASQAAQASSPAPGPASQPAPAPAPAQGNSSGNGKDAGQNNSDKGKGKN
>NZ_CP041187.1|WP_141161241.1|4313058_4314027_+|hypothetical-protein
MTRTRSLASGLLTLSAAAVLTLTAAGGASADPAPSDGNEAPSVASVTLDAGAAADYWTPERMQGAVPGDTLAGKALERGNRSNPALVEKGKPSSTKATKGKPTLAQSANPVSHIGKVFFTLGGTNYVCSGNAVTSTNRSTVATAGHCVNEGPGAYATNFVFVPAYDNGAAPYGKWTAKALYAPTQWASNGDMTYDTGFAVMNPDAKGRKLTDVVGGSGTAFNQARGLTYTSYGYPAAAPFNGETLKSCTGTASNDSNNPQFNTQGIPCDMTGGSSGGPWFIGNGPDGLQNSINSYGYNGSAVMYGPYWGSVIETTYTNAAKS
>NZ_CP041187.1|WP_168225762.1|4314010_4314181_+|hypothetical-protein
MPRNPKEPAPDQDPVSHVDLNQSPEEVLEYWTDERMAAAKPREIQLPEPEPPAGQD
>NZ_CP041187.1|WP_141161242.1|4314257_4315943_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MSFTQHERVSIDRVPIRRALISVYDKTGLEELASGLHAAGVKLVSTGSTAKKIAAAGIPVQEVEEVTGSPEMLDGRVKTLHPRVHGGILADRRVPAHMETLASMDIEAFDLVVVNLYPFVETVKSGAAQDDVVEQIDIGGPAMVRSAAKNHAAVAIVVDPSFYGQVVEAAAEGGFDLKTRRRLAAKAFAHTAAYDNAVATWTASQFLDEDGDGVIDWPAYAGLSLERSEVLRYGENPHQQAALYVDKAAPVGIAQADQLHGKAMSYNNFVDADAALRAAYDFSEPAVAVIKHANPCGVAVGSKDAADPIADAHAKAHACDPVSAFGGVIAANRTVTAGMANTVKDIFTEVVIAPGFEPEAVEILSKKKNIRLLALPEGYGRYPTEFRQVSGGMLVQVSDKVDADGDNPANWTLAAGEAADEKTLADLAFAWTACRAAKSNAILIADNGAAVGIGMGQVNRLDSCRLAVERANTLGVTVESDVDGAGGASNADASGAPERARGAVAASDAFFPFADGLQILIDAGVRAVVQPGGSVRDEEVIAAANAAGITMYFTGARHFFH
>NZ_CP041187.1|WP_141161243.1|4316086_4317439_+|MFS-transporter
MNTYTTVPSGEQVVQELPWRWKVQGRIFLIGGLGFMFDAWDVTLNGILIPLLSKHWSLSAGEAAWVGTANLIGMALGAFIWGTIADTLGRKKAFTATLLLFSVFTVLGAFAPDFVWFCVFRFMAGFGLGGCIPVDYALVGEFTPRKQRGKVLTAMDGWWPVGAALAGFVSAGLVALFGDWRLTMLVMVLPALLVFWIRRSVPESPLFLIRKGRREEAAKIIDGLVEATGAEPRAYSLPDARDVPRLSAGSAWTQLRSVWQFNWKITAAAWSLFFSILLVYYLSLTWMPRILIGAGFAEYKAFVTTASMAAVGFLGVVVAALLVERVGRKWILAITGPLSALTLVIVAFVVDIPTAAVFWLLVFGFVVQVAIPVLYAYVSELYPTELRGTGFGWASTFSRLGAGFGPLVFANYFWPELGLATSFALAGALVLASVLWMAFFSPETRRARLQ
>NZ_CP041187.1|WP_141161244.1|4317575_4318157_-|phosphoribosylglycinamide-formyltransferase
MRIVVLVSGTGSNLQAVIDAVKAGELDVEIAAVGADREGTYGVERSAAAGIPTFVVDFKAYPDRTDWNAALAGAVAAYSPDVVVSSGFMRIVSPDFIDAFNGRYLNTHPALLPAFPGAHGVRDAMAYGVKVTGCTVHWADAGVDTGPIIAQEAVAIEDADTEETLHERIKVVERRLLVSTLAALAADPEYSAA
>NZ_CP041187.1|WP_141161245.1|4318196_4318628_+|hypothetical-protein
MNSEPGRAGRQQARPPLSEAAKASLAKTHTLFRTFVVTVLGAFFVYQLDVGYLWLTSLLTLASLVLGIVLLVRSIRLKESRLVLVGTISGLVVAAVMVLLIVTTLVLFDQVREYQACLGRALTDRATQACMVQFQDVLPARIP
>NZ_CP041187.1|WP_141161246.1|4318641_4319958_-|hypothetical-protein
MKLRADQTGDRGLPMPLWLQGALEAAQAAIISALVVVAPIVAVWATAGFQNGQFEVLARLAGQSWLLVHGVPLELAGAGPATATHGGSGTLSLIPLGLTVIPFLLAWRAGRRLARASYTDQLWQALLGSWAVYAAFGAATGFVCRSSDVVINLWYAILVPLVPFGLGMVVGARREAGSWSRLIGVDAVDWISRTSQHSRWAGSYLASAAKAGFVAVASALTLAATLLAVDLFIHWNLVVSVYEALDAGPVGGAALTIAQLGFLPNLVVFALAWTSGAGFALGAGSQAGALGTAVGPLPSIPVLAAIPSGSLDYAVVALVVPVLAGVMAGWWFLREGENHFDEWLAIKVHARWFTATVSTLVLGVLAGLAAGLLVMGLAWIARGSAGLGRLTAIGPDPLWTALWVAAEVAAGVVIGYAAGPWLEREKAGAADREGELVH
>NZ_CP041187.1|WP_141161247.1|4320397_4321240_-|DUF2382-domain-containing-protein
MLNRENLENLLTKGGHVVGSDGTKIGSIGQLYADDDTGEPTWVTVKTGLFGTSESFVPVEGANNQGEDLVVPFTKEHVKDAPRVDADGHLTPEEEDRLYTYYDRGARTYTEATRDTAGDVDLQGDADLNAGTPTAGITSAADTHTRGTVGHDTSGPTTDDAMTRSEEQLRVGKERETTGRARLRKYVTTENVTKTIPVEREEVRVEREPITDANRGSALDGPGISEEEHEVVLHEERPVVEKETVPVERVRLDKETVHDDVTVNEEVRKENIETDGDARR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

183164 : 191646

Bacillus_phage(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_141158043.1\|183164_184676_+	HAMP domain-containing protein	W8CYF6	Bacillus_phage	2.2e-25	32.9
WP_141158044.1\|184780_185068_+	WXG100 family type VII secretion target	NA	NA	NA	NA
WP_141158045.1\|185076_186087_-	DUF4440 domain-containing protein	A0A142CJN1	Brazilian_marseillevirus	1.6e-19	38.7
WP_141158046.1\|186255_187890_-	chaperonin GroEL	A0A240F779	uncultured_virus	3.4e-149	54.3
WP_141158047.1\|188180_189449_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_141158048.1\|189448_189655_-	cold shock domain-containing protein	Q9AZD3	Lactococcus_phage	3.1e-15	58.2
WP_141158049.1\|189720_190359_-	LytR family transcriptional regulator	NA	NA	NA	NA
WP_141158050.1\|190411_190741_-	DUF3263 domain-containing protein	A0A2H4PF05	Gordonia_phage	8.2e-10	47.1
WP_141158051.1\|190875_191646_+	uracil-DNA glycosylase	S4VYQ4	Pandoravirus	6.4e-29	39.2

DBSCAN-SWA_2

394762 : 452569

Gordonia_phage(20.0%)

tRNA,integrase,transposase,protease

attL 424310:424325|attR 454413:454428

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_141158193.1\|394762_396049_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	3.1e-60	35.9
WP_141158194.1\|396084_396834_+	dienelactone hydrolase family protein	NA	NA	NA	NA
WP_141158195.1\|397009_397948_+	hypothetical protein	NA	NA	NA	NA
WP_141158196.1\|398070_398832_-	queuosine precursor transporter	A0A1W7AG82	Streptococcus_virus	1.0e-18	34.1
WP_141158197.1\|399029_399686_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_141158198.1\|399707_400619_+	TIGR01777 family protein	NA	NA	NA	NA
WP_141158199.1\|400615_401026_+	hypothetical protein	NA	NA	NA	NA
WP_141158200.1\|401097_401955_+	hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_141158201.1\|402046_403795_-	pyruvate dehydrogenase	NA	NA	NA	NA
WP_141158202.1\|403957_405349_-	MFS transporter	Q6JIH2	Burkholderia_virus	3.7e-35	27.5
WP_141158203.1\|405589_406261_+	response regulator	NA	NA	NA	NA
WP_141158204.1\|406257_407709_+	HAMP domain-containing protein	NA	NA	NA	NA
WP_141161371.1\|407692_408715_+	TAXI family TRAP transporter solute-binding subunit	NA	NA	NA	NA
WP_168225704.1\|408931_409243_+\|transposase	transposase	NA	NA	NA	NA
WP_168225705.1\|409879_411277_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.2e-28	30.1
WP_168225706.1\|411260_411584_+\|transposase	transposase	Q6J1X2	Lactobacillus_phage	1.3e-07	36.2
WP_141158208.1\|411706_413191_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_141158209.1\|413367_414684_+	isocitrate lyase	NA	NA	NA	NA
WP_141158210.1\|414795_416448_+	malate synthase A	NA	NA	NA	NA
WP_141158211.1\|416705_417899_-	MFS transporter	NA	NA	NA	NA
WP_141158212.1\|418044_419004_+	D-2-hydroxyacid dehydrogenase family protein	A0A1J0F959	Only_Syngen_Nebraska_virus	3.9e-20	27.2
WP_141158213.1\|419020_419554_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_141158214.1\|419559_421740_-	amylo-alpha-1,6-glucosidase	NA	NA	NA	NA
WP_141158215.1\|421798_422860_-	glycosyltransferase	NA	NA	NA	NA
WP_141158216.1\|423074_423773_+	DsbA family oxidoreductase	NA	NA	NA	NA
WP_141158217.1\|423808_424459_+	TetR family transcriptional regulator	NA	NA	NA	NA
424310:424325	attL	NA	NA	NA	NA
WP_141158218.1\|424489_425164_-	LytR family transcriptional regulator	NA	NA	NA	NA
WP_141158219.1\|425156_425459_-	type II toxin-antitoxin system VapB family antitoxin	NA	NA	NA	NA
WP_141158220.1\|425599_426529_+	hypothetical protein	NA	NA	NA	NA
WP_141158221.1\|426605_428243_+	sugar phosphotransferase	NA	NA	NA	NA
WP_141158222.1\|428297_429224_-	phosphodiesterase	NA	NA	NA	NA
WP_141158223.1\|429384_429897_-	redoxin domain-containing protein	NA	NA	NA	NA
WP_141161373.1\|429949_431413_-	peptidoglycan DD-metalloendopeptidase family protein	V5R8R0	Arthrobacter_phage	1.2e-20	47.7
WP_141158224.1\|431790_432726_+	DUF2236 domain-containing protein	NA	NA	NA	NA
WP_141158225.1\|433396_436804_+	DNA polymerase III subunit gamma and tau	A0A1L2BWV7	Bacteriophage	4.3e-45	35.0
WP_141158226.1\|436879_437479_+	recombination protein RecR	NA	NA	NA	NA
WP_141158227.1\|437695_439054_+	aspartate kinase	NA	NA	NA	NA
WP_141158228.1\|439139_439355_-	hypothetical protein	NA	NA	NA	NA
WP_141158229.1\|439474_439717_-	hypothetical protein	NA	NA	NA	NA
WP_141158230.1\|439793_440258_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_141158231.1\|440331_440892_+\|protease	serine protease inhibitor	NA	NA	NA	NA
WP_141161374.1\|440869_441802_+	3-methyladenine DNA glycosylase	NA	NA	NA	NA
WP_141158232.1\|441798_442131_+\|protease	serine protease inhibitor	NA	NA	NA	NA
WP_141161375.1\|442205_445313_-	S8 family serine peptidase	NA	NA	NA	NA
WP_141158233.1\|445590_445776_-	hypothetical protein	NA	NA	NA	NA
WP_015935902.1\|446023_446275_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_141158234.1\|446276_447050_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_141158235.1\|449429_449723_-	DUF503 family protein	NA	NA	NA	NA
WP_141158236.1\|449731_450052_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_141158237.1\|450048_450597_-	DUF1990 family protein	NA	NA	NA	NA
WP_141158238.1\|450873_451506_+	hypothetical protein	A0A2H4PF11	Gordonia_phage	1.4e-50	55.4
WP_141158239.1\|451465_452569_-\|integrase	tyrosine-type recombinase/integrase	A0A0E3XBN7	Gordonia_phage	3.7e-46	35.6
454413:454428	attR	NA	NA	NA	NA

DBSCAN-SWA_3

456656 : 476672

Arthrobacter_phage(29.41%)

coat,portal,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_141158249.1\|456656_457598_+	hypothetical protein	A0A2H4JA52	uncultured_Caudovirales_phage	2.5e-27	30.6
WP_141158250.1\|457590_458391_+	hypothetical protein	A0A0K0MWX8	Gordonia_phage	2.7e-14	30.7
WP_141158251.1\|458387_458729_+	hypothetical protein	NA	NA	NA	NA
WP_141158252.1\|458884_459346_+	single-stranded DNA-binding protein	A0A286N316	Arthrobacter_phage	2.5e-57	91.1
WP_141158253.1\|459604_459847_+	hypothetical protein	NA	NA	NA	NA
WP_141158254.1\|459843_460764_+	hypothetical protein	A0A159B6E8	Gordonia_phage	9.9e-29	32.6
WP_141158255.1\|460760_460979_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_141158256.1\|460978_461338_+	hypothetical protein	NA	NA	NA	NA
WP_141158257.1\|461516_461972_+	hypothetical protein	NA	NA	NA	NA
WP_141158258.1\|461971_462700_+	hypothetical protein	A0A173G9J5	Propionibacterium_phage	5.5e-22	28.3
WP_141158259.1\|462696_464034_+	AAA family ATPase	V5R9D2	Arthrobacter_phage	9.8e-110	50.0
WP_141158260.1\|464033_464396_+	hypothetical protein	A0A2P1N2X9	Mycobacterium_phage	2.1e-11	41.7
WP_141158261.1\|464513_464693_+	hypothetical protein	NA	NA	NA	NA
WP_168225710.1\|464810_464984_+	hypothetical protein	NA	NA	NA	NA
WP_141161376.1\|465097_465484_+	hypothetical protein	A0A140G6H3	Arthrobacter_phage	1.9e-18	50.5
WP_141158262.1\|465480_465792_+	hypothetical protein	NA	NA	NA	NA
WP_141158263.1\|465784_466030_+	hypothetical protein	NA	NA	NA	NA
WP_141158264.1\|466026_466392_+	hypothetical protein	V5RBF1	Arthrobacter_phage	2.5e-07	51.3
WP_168225711.1\|466453_466597_+	hypothetical protein	NA	NA	NA	NA
WP_141158265.1\|466715_467513_+	hypothetical protein	NA	NA	NA	NA
WP_141158266.1\|468190_468691_+	hypothetical protein	A0A1J0MCL8	Streptomyces_phage	2.8e-09	44.7
WP_141158267.1\|468687_469956_+\|terminase	PBSX family phage terminase large subunit	A0A1J0MC90	Streptomyces_phage	2.7e-101	48.5
WP_141158268.1\|469982_470243_+	hypothetical protein	A0A249XN41	Arthrobacter_phage	4.2e-17	52.9
WP_141158269.1\|470259_471927_+\|portal	phage portal protein	A0A1J0MBZ7	Streptomyces_phage	1.0e-87	37.9
WP_141158270.1\|471946_473065_+	hypothetical protein	A0A1J0MCS2	Streptomyces_phage	2.4e-37	35.6
WP_141158271.1\|473074_473374_+	ammonia monooxygenase	F8TVC3	EBPR_siphovirus	1.3e-14	42.2
WP_141158272.1\|473373_473880_+	hypothetical protein	NA	NA	NA	NA
WP_141158273.1\|473876_474533_+	hypothetical protein	NA	NA	NA	NA
WP_141158274.1\|474560_475409_+\|coat	P22 coat protein - protein 5 domain protein	D7NW53	Streptomyces_phage	4.5e-68	49.3
WP_141158275.1\|475427_475790_+	hypothetical protein	NA	NA	NA	NA
WP_141158276.1\|476219_476672_+	hypothetical protein	G9FH89	Rhodococcus_phage	1.6e-08	40.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage