CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP035368	Haemophilus parainfluenzae strain LC_1315_18 chromosome, complete genome	1 crisprs	DEDDh,cas14j,DinG,cas3	0	1	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP035368_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP035368_1

722423-722592

TypeV

Consensus_repeat	Method
GTTGTAGCTCCCTTTTTCATTTCGCAGTGCTATAATCC	PILER-CR

2 spacers

cas14j

The CRISPR arrays of NZ_CP035368_1

>merge|NZ_CP035368|1|722423-722592|PILER-CR
GTAATAACACCCTTTTTCATTTCGCAGTGCTATAATCCGCACTTTTAGCGGTAGCAGATATGCCGCGTTGTAGCTCCCTTTTTCATTTCGCAGTGCTATAATCACATTCTTCTACCTTGCAACGGTGTTCTGGTTGTAGCTCCCTTTTTCATTTCGCAGTGCTATAATCC

>NZ_CP035368|1|1|722423-722592|PILER-CR
GTAATAACACCCTTTTTCATTTCGCAGTGCTATAATCC	GCACTTTTAGCGGTAGCAGATATGCCGC
GTTGTAGCTCCCTTTTTCATTTCGCAGTGCTATAATCA	CATTCTTCTACCTTGCAACGGTGTTCTG
GTTGTAGCTCCCTTTTTCATTTCGCAGTGCTATAATCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP035368.2\|WP_128787147.1\|721486_722101_+\|riboflavin-synthase-subunit-alpha	unknown	unknown	gnl\|CDD\|183846
NZ_CP035368.2\|WP_128787155.1\|732531_733326_+\|tRNA-pseudouridine(38-40)-synthase-TruA	unknown	unknown	gnl\|CDD\|234577
NZ_CP035368.2\|WP_128787144.1\|716888_718403_-\|sodium/proline-symporter-PutP	unknown	unknown	gnl\|CDD\|273981
NZ_CP035368.2\|WP_128787140.1\|712368_713400_-\|branched-chain-amino-acid-aminotransferase	unknown	unknown	gnl\|CDD\|237363
NZ_CP035368.2\|WP_128787150.1\|727641_727998_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271181
NZ_CP035368.2\|WP_128787152.1\|729062_729248_-\|type-II-toxin-antitoxin-system-HicA-family-toxin	unknown	unknown	gnl\|CDD\|377942
NZ_CP035368.2\|WP_128787145.1\|718520_719996_+\|ribonuclease-G	unknown	unknown	gnl\|CDD\|183285
NZ_CP035368.2\|WP_149785862.1\|728150_728603_+\|DUF1367-family-protein	unknown	unknown	gnl\|CDD\|369209
NZ_CP035368.2\|WP_005643263.1\|728603_729032_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|374224
NZ_CP035368.2\|WP_128787156.1\|733391_734282_+\|acetyl-CoA-carboxylase,-carboxyltransferase-subunit-beta	unknown	unknown	gnl\|CDD\|235547
NZ_CP035368.2\|WP_128787153.1\|729674_730421_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP035368.2\|WP_014065570.1\|727205_727493_+\|50S-ribosomal-protein-L25	unknown	unknown	gnl\|CDD\|180318
NZ_CP035368.2\|WP_128787149.1\|726373_726979_-\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP035368.2\|WP_128787148.1\|722129_722405_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP035368.2\|WP_128787142.1\|714775_715864_+\|23S-rRNA-(cytidine(2498)-2'-O)-methyltransferase-RlmM	unknown	unknown	gnl\|CDD\|236971
NZ_CP035368.2\|WP_128787141.1\|713889_714783_+\|transcriptional-regulator-GcvA	unknown	unknown	gnl\|CDD\|182990
NZ_CP035368.2\|WP_128787139.1\|708851_712301_+\|acyl-[ACP]--phospholipid-O-acyltransferase	unknown	unknown	gnl\|CDD\|236315
NZ_CP035368.2\|WP_128787146.1\|720043_721441_-\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|234981
NZ_CP035368.2\|WP_128787143.1\|715923_716889_-\|tRNA-5-methoxyuridine(34)/uridine-5-oxyacetic-acid(34)-synthase-CmoB	unknown	unknown	gnl\|CDD\|237898
NZ_CP035368.2\|WP_128787154.1\|730999_732136_+\|transposase	cas14j	-	gnl\|CDD\|223747

Protein	Function_ID	Function_description	E-value
NZ_CP035368.2\|WP_128787147.1\|721486_722101_+\|riboflavin-synthase-subunit-alpha	gnl\|CDD\|183846	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional.	3.1842e-115
NZ_CP035368.2\|WP_128787155.1\|732531_733326_+\|tRNA-pseudouridine(38-40)-synthase-TruA	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	2.18437e-147
NZ_CP035368.2\|WP_128787144.1\|716888_718403_-\|sodium/proline-symporter-PutP	gnl\|CDD\|273981	TIGR02121, Osmoregulated_proline_transporter, sodium/proline symporter. This family consists of the sodium/proline symporter (proline permease) from a number of Gram-negative and Gram-positive bacteria and from the archaeal genus Methanosarcina. Using the related pantothenate permease as an outgroup, candidate sequences from Bifidobacterium longum and several from archaea are found to be outside the clade defined by known proline permeases. These sequences, scoring between 570 and -40, define the range between trusted and noise cutoff scores. [Transport and binding proteins, Amino acids, peptides and amines].	0
NZ_CP035368.2\|WP_128787140.1\|712368_713400_-\|branched-chain-amino-acid-aminotransferase	gnl\|CDD\|237363	PRK13357, PRK13357, branched-chain amino acid aminotransferase; Provisional.	0
NZ_CP035368.2\|WP_128787150.1\|727641_727998_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271181	cd00800, INT_Lambda_C, C-terminal catalytic domain of Lambda integrase, a tyrosine-based site-specific recombinase. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome. They are tyrosine-based site-specific recombinase and belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The phage lambda integrase can bridge two different and well-separated DNA sequences called arm- and core-sites. The C-terminal domain binds, cleaves and re-ligates DNA strands at the core-sites, while the N-terminal domain is largely responsible for high-affinity binding to the arm-type sites.	1.36078e-12
NZ_CP035368.2\|WP_128787152.1\|729062_729248_-\|type-II-toxin-antitoxin-system-HicA-family-toxin	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	2.18541e-12
NZ_CP035368.2\|WP_128787145.1\|718520_719996_+\|ribonuclease-G	gnl\|CDD\|183285	PRK11712, PRK11712, ribonuclease G; Provisional.	0
NZ_CP035368.2\|WP_149785862.1\|728150_728603_+\|DUF1367-family-protein	gnl\|CDD\|369209	pfam07105, DUF1367, Protein of unknown function (DUF1367). This family consists of several highly conserved, hypothetical phage proteins of around 200 residues in length. The function of this family is unknown. Some proteins are annotated as IrsA (intracellular response to stress).	1.76722e-18
NZ_CP035368.2\|WP_005643263.1\|728603_729032_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|374224	pfam15919, HicB_lk_antitox, HicB_like antitoxin of bacterial toxin-antitoxin system. This is a family of HicB-like antitoxins.	1.18482e-28
NZ_CP035368.2\|WP_128787156.1\|733391_734282_+\|acetyl-CoA-carboxylase,-carboxyltransferase-subunit-beta	gnl\|CDD\|235547	PRK05654, PRK05654, acetyl-CoA carboxylase carboxyltransferase subunit beta.	0
NZ_CP035368.2\|WP_128787154.1\|730999_732136_+\|transposase	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	7.55058e-50
NZ_CP035368.2\|WP_128787139.1\|708851_712301_+\|acyl-[ACP]--phospholipid-O-acyltransferase	gnl\|CDD\|236315	PRK08633, PRK08633, 2-acyl-glycerophospho-ethanolamine acyltransferase; Validated.	0
NZ_CP035368.2\|WP_128787149.1\|726373_726979_-\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	7.06472e-44
NZ_CP035368.2\|WP_128787142.1\|714775_715864_+\|23S-rRNA-(cytidine(2498)-2'-O)-methyltransferase-RlmM	gnl\|CDD\|236971	PRK11760, PRK11760, putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional.	0
NZ_CP035368.2\|WP_128787141.1\|713889_714783_+\|transcriptional-regulator-GcvA	gnl\|CDD\|182990	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional.	1.20646e-176
NZ_CP035368.2\|WP_014065570.1\|727205_727493_+\|50S-ribosomal-protein-L25	gnl\|CDD\|180318	PRK05943, PRK05943, 50S ribosomal protein L25; Reviewed.	8.06345e-54
NZ_CP035368.2\|WP_128787146.1\|720043_721441_-\|MATE-family-efflux-transporter	gnl\|CDD\|234981	PRK01766, PRK01766, multidrug efflux protein; Reviewed.	0
NZ_CP035368.2\|WP_128787143.1\|715923_716889_-\|tRNA-5-methoxyuridine(34)/uridine-5-oxyacetic-acid(34)-synthase-CmoB	gnl\|CDD\|237898	PRK15068, PRK15068, tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB.	0

>NZ_CP035368.2|WP_128787148.1|722129_722405_+|hypothetical-protein
MFKDEIALIRFLGREFIVVFNVFFLFPLSIILVLIGVIHGVIWNVLLGIVFTYLVFLVLFRILIYFLYKKWEREHQKKMQEENKVKYIIIK
>NZ_CP035368.2|WP_128787147.1|721486_722101_+|riboflavin-synthase-subunit-alpha
MFTGIVQGIAQIHAIKDSDNFRTQIVKLPAEMRKGLEIGASVANNGVCLTVTEIHDELVSFDLMQETLRITNLGNLKAGDFVNIERAMQMGAEIGGHILSGHVYCTASVSQIIESENNRQVWFKLPTKDVMKYILTKGFIAIDGISLTIGEVKGDEFCVNLIPETLHRTLIGKRQIGDLVNIEIDPQTQAIVDTVENYLKARGI
>NZ_CP035368.2|WP_128787146.1|720043_721441_-|MATE-family-efflux-transporter
MNSRLFSQYRIDIQKLIRIATPIGLAQLAQTGMGTVDVIMAGRVSSVDVGGVGIGASIWLPLVLFGQGLLLALPPTISYLNGSGQRHRIAHQVRQGLWISFLVMIPLVLIIYHNDFILQFMNMDTHMADVTMNYLRAMVWGLPAYLLLINFRCLNDGIAKTKPAMVITFMGLMLNIPLNYMFIYGKFGAPALGGVGCGVATAIVNWAMAILMITYSAKNYNERSLKVFEKIIEKPDIKTLKKLTALGLPIAIALCSEVSLFALSSLLLSPLGADVVASHQIALNTSAVAFMFPMSIAMAATILVAQELGNHAPQKAKIMAHAAIILGLIAASVLALVIWVFSAEIAALIVGDNATVIALSGSLLAMAAIYQFSDSVQVVVSGILRGYKDTKIILYITLLAYWGVGIPVGYILSRTDWIVPSIGAKGFWVAFIIALTIAATLLFIRMRKIQSQPDEAIIQQLERLK
>NZ_CP035368.2|WP_128787145.1|718520_719996_+|ribonuclease-G
MNSVELLMNVTPNETRVALVETGVLKEVHIERQAKRGIVGNIYKGRVTRVLPGMQSAFVDIGLEKAAFLHASDIVSHTECVDVNEQKQFRAKSISELVREGQDIVVQVVKDPLGTKGARLTTDITLPSRYLVFMPENSHVGVSQRIESEEERARLKALVEPFCDELGGFIIRTATEGATEEELRQDAEFLKRLWRKVLERKGKYPTRSKIYGEPALPQRILRDFIGANLEKIHIDSKLCFNEVKEFTDEFMPELSEKLMLYTGSQPIFDIYGVERGIQNALEKRVNLKSGGYLIIEQTEAMTTIDINTGAFVGHRNLDETIFNTNIEATKAIAQQLQLRNLGGIIIIDFIDMQTDEHRNRVIESLEDALSKDRVKTNVNGFTQLGLVEMTRKRTRESLEHVLCDECPTCQGRGRVKTVETVCYEIMREIIRVNHLFSSEQFVVYASPAVADYLIKEESHGLLPEVEMFISKQVQVKTEQYYNQEQFDVVVM
>NZ_CP035368.2|WP_128787144.1|716888_718403_-|sodium/proline-symporter-PutP
MFGLDPTLITFSIYIFGMILIGVLAYYYTNNLSDYILGGRKLGSFVTAMSAGASDMSGWLLMGLPGAVYVSGLVEGWIAIGLILGAYFNWLLVAGRLRIYTEFNNNALTLPEYFYHRFGTKHHLLKIVSASIILVFFTIYCASGVVAGAKLFQNLFSVDYSTAIWYGALATIIYTFIGGFLAVSWTDTIQATLMIFALILTPLFIFLSLGDASQFTESLHQAEIAASKDFTDLFSSTTPLGLLSLAAWGLGYFGQPHILARFMAAYSVKSLIKARRISMTWMVICLAGAIGIGFFGIPYFFANPDVAGIVNNEPEQVFIELSKLLFNPWIAGILLSAILAAVMSTLSAQLLISSSSITEDFYKGFIRPKAAEKELVWLGRAMVLVIAGIAIWIAQDENSKVLKLVEFAWAGFGSAFGPVVLFSLFWKRMTSSAALIGMIVGATVVFSWKYVIPKTSEWFNVYEMIPGFTLASLAIIVVSLLSAEPENEVKETFEKAEKAYKEAK
>NZ_CP035368.2|WP_128787143.1|715923_716889_-|tRNA-5-methoxyuridine(34)/uridine-5-oxyacetic-acid(34)-synthase-CmoB
MIDFRPFYQQIATTNLSAWLETLPLQLKEWEKQTHGDYAKWSKIVDFLPDLQADTIDLKNAVKSDRTSPLLEGEKQRIIHHLKQLMPWRKGPYHLFDIHVDCEWRSDFKWDRVLPHLAPLKDRTILDVGCGSGYHMWRMVGEDAKMVVGIDPTELFLCQFEAVRKLLNNDRRANLIPLGIEEMQPLAAFDTVFSMGVLYHRKSPLDHLTQLKNQLVKGGELVLETLVVDGDVNTVLVPSDRYAKMKNVYFIPSVAALINWLEKVGFTNVRCVDVATTTLEEQRKTDWLENESLIDFLDPNDHSKTIEGYQAPTRAVILANK
>NZ_CP035368.2|WP_128787142.1|714775_715864_+|23S-rRNA-(cytidine(2498)-2'-O)-methyltransferase-RlmM
MNKLALYCRIGFEKEVAAEITDRASERGVFGFARVVENSGYVIFECYQPGDADRLAREIPFNRLIFARQMIVVSDFLENLDPQDRISPILAQYKRIAEDINLKQAVELFVETADTNEAKALSTFCRKFTVPLRQALKKQGWLQGKPNAKRGQILHCFFTQPNCCYVGYSYLGNNSTHFMGIPRLKFPADAPSRSTLKLEEAILTFIPRHEESKRLNENMVGVDLGACPGGWTYQLVKRGLFVYAVDHGKMVASLHDTGRIEHCPEDGFKFQPPKRKHIDWLVCDMVEQPSRIANLIGKWLINGWCRETIFNLKLPMKKRYQEVMLCLENLAVMLAEKELEFDIQAKHLYHDREEITVHIALK
>NZ_CP035368.2|WP_128787141.1|713889_714783_+|transcriptional-regulator-GcvA
MYKRLPPLNSLKSFESAARHLSFTKAADELCVTQAAVSHQIKLLEDFLGVELFIRKNRSLELTEFGKAYFIDINKILRKLNEATERLLTLKAEPHLTISVPQTFGIQWLVPHLSDFNKQHPEIEVRLKGVDQDEGLLNKEIDIAIYYGKGDWENLQVDRLVEENLVILAAPSLLEKTAVHTPDDLKKHTLIHTHTRDNWQAMADYLKLDDLNIQQGPLFSHTFMALQAAVHGQGIALSNRILAQQEIENGHLQIVLPTELRDPKSFYVVNHLDHLDDEQIQAFRTWIKDSIKLGKHE
>NZ_CP035368.2|WP_128787140.1|712368_713400_-|branched-chain-amino-acid-aminotransferase
MKDLDWNNLGFSYIKTDYRFIAHWKDGKWDEGKLTTDNMLHIHEGSTAIHYGQQCFEGLKAYRCKDGSINLFRPDQNAKRMQHTSDRLLMPQVPTELFIRACKEVVKANQEWLGPYGSGATLYLRPFLFGTGANIGVKTAPEFIFSVFCCPVGAYFKGGLAPSNFITTDYDRAAPMGTGGVKVGGNYAASLLPHELAAEAGTPERKFADAIYLDPKTHTKIEEVGAANFFGITKDNKFITPASDSILPSITKYSLLHIAKERLGMKAIEGDVYIDQLDQFAEAGACGTAAVITPVGGIQHKGKFHVFYSETEVGPVTRKLYNELTGIQFGDVEAPEGWIVKVE
>NZ_CP035368.2|WP_128787139.1|708851_712301_+|acyl-[ACP]--phospholipid-O-acyltransferase
MKLLKYAGFVPYLAIAFINASVDLAHKITIQNVLLKSFSGESLVVLTALINAMILLPFIFLFSPSAFINDKFSRTNVIRYSSLAAVVISAGILLSYMTGMFAISFVLTLILAAQSAVYSPAKYSIIKSIVGTENIGMANGVIQALTIVAILFSSFAFSFFFEAHYVASDDPNEVLQSVWVIGVALVLLSALEAYFAFKIPFFKQEAENTDGQFDMRKYLSLGYLKDNVRTLKADQNIWLSVIGLSLFWGVSQIIVAAFPAHYKAMFNEDNAIVIQAILAVSGIGLALGSYLAGRASRLHIELGIVPLGALGICASLFFLTFAQSGVVLALCSFVFGFSGGLLIVPLNATIQYFAPEKISGKIMAGNNFVQNVFMVVFLLLSIVFVQLNVSTQSLFLVTSATCFAASLYTMSKVPHLFTRLFLLFALKASYRFHVDGLKNLPQSGGVLLLGNHISWIDWLVLQAASPRAIKFVMYRPIYNKWYLTWFFRIFKVIPIGGGSSRESIETIREYLARGEVVVLFPEGHISYNGQINEFQKGFEHVLKDLENVTTVPFYLRGLWGSSFSRADSFYKNLTKRQGKREILVAFGKPIHGFIDATAMKQKVLELSFSVWEKVMSKRKPLMHHWLNSAKSNLFKEATVDAQGTKLNNLKFIAAVLMFVKTLKSALGNEKNVGVLLPSSSIGAIINMTLMVMGKVPVNLNYTLSPEVMEKALKKANISQVITSEKFLDKLNAKGFDFSQVVADKALFMENLGKSITKANKVRSFLTAFLAPQWWIKLRYFADVSLEDNATILFSSGSEGDPKGIELSHKNLLTNIKQIGELLNFHKDDVILNSLPIFHSFGLTVTTLLPLCEGIKMVSVADPTDGATVGKMCARHRVSILFGTSTFFRLYVRNKKFHPLMLQNVRMVIAGAEKLKADVKEAFKLKFGLDIYEGYGATETAPVASVNMPNLLDPETLQEFTFNQAGTVGMPLPGTIIKIVDPESLQELPVGEDGLILIGGGQVMKGYLNAPEKTAEVIVEIDGVRYYKTGDKGHIDHNGFITIVDRYSRFAKVGGEMISLGSVEEKLSQVFDEENQFVAVALSDDKKGESIVLLIKSALSLDEINERIKGLNVPPIMLPSQVFLVDEIPMLGSGKVDFKGAKNLAMSLVK
>NZ_CP035368.2|WP_128787149.1|726373_726979_-|DedA-family-protein
MEFLISFFTDYGYWAVLFVLIICGFGVPIPEDITLVSGGVIAGLYPESVNSHLMLLVSMIGVLAGDSCMYWLGRIYGTRILRFRPMRKVITLQRLKMVREKFAQYGNRVLFVARFLPGLRAPIYMVSGITRRVSYTRFVLIDFCAAIISVPIWVYLGEFGARNLDWLHEQIQKGQIVIYILVGALAVFLFWKWKKAKKQAK
>NZ_CP035368.2|WP_014065570.1|727205_727493_+|50S-ribosomal-protein-L25
MAFKFNAEVRQAQGKGASRRLRHNGQIPAIIYGGSEAPVSIILNHDELNNAQVHDSFYSDVITLVVEGKEVAVKVQAMQRHPFKPKLVHIDFKRA
>NZ_CP035368.2|WP_128787150.1|727641_727998_-|tyrosine-type-recombinase/integrase
MPSTLKRVAIKVIGKLKEIIDKRITEENQFLFTNKWGRKLERRSLTDYFKDTRNAASIKYKELAEEINQVQLRDLRAKAATDLSLMIDDERARKQLGHTSARTTQHYIRKEKPLNPTK
>NZ_CP035368.2|WP_149785862.1|728150_728603_+|DUF1367-family-protein
MQLEMLKIEGGMLAPLDDMQAEVLMKFKTGEQYQVEIKKARNPAFHRKVFAFFKFCFDHWAADKTEWEHFDERKQFDTFRKHLTVLAGFYESTYNIKGNLRIEAQSLSYGNMEQAEFESCYKALISAAIKHIFNDTTDENTLNQLYAFFG
>NZ_CP035368.2|WP_005643263.1|728603_729032_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MLFTIGIETPTNENEAYGITVPALFTEEYSCFSAADTLEEIPTQVTDAIHSILEMMFEDGIDINALQDKGYRHYQTQEDFNYCDTWLLLDVDISAYQGKRHRINISLPEYLIKRIDSRVASNPIYKDRSHFLAIASQKELRQ
>NZ_CP035368.2|WP_128787152.1|729062_729248_-|type-II-toxin-antitoxin-system-HicA-family-toxin
MRSSDLIKELKNAGCTFVRHGKGDHQIWQSPITGKTFPIPHPKQHVPIGTLRSIKKSAGLL
>NZ_CP035368.2|WP_128787153.1|729674_730421_+|hypothetical-protein
MFDQLLYLSRVPQKAQKKTSPIVANRGADVILDNADEDAPDNRLALYQEQVVAIEALNYFTEWCETKEDELEDGEGFGDRLLGLMVAVADDNQDGELDDDEQELVTIGLNAVYDYMISKGVSEENAASLLDDFDNDLARNIHQFILGKLPQGEDEMQDEMDALIFSTEENEPMLDSAISMEIITDAAYRKVFAIRNGKKLRINKRISGKVRLSAKQRQAIRKAQRRANTGAAKMRRLKSFRMRRRAGL
>NZ_CP035368.2|WP_128787154.1|730999_732136_+|transposase
MQLRKAFKFEIMPNGEQIRIIKQFCGCSRFVFNRALACQNEQYEQDNSVKFSYTKIANLLPHWKKELLWLKDCHSQVLQQSLKDLESAFKNFFQKRSDFPKFKKKGLKESFRFPQGCKLEQQNNRLYLPKIGWIRYRNSRDVIGEIKNVTVSQKCGRFFASIQTEFEYEIPTHQGGEIGIDMGVARFATLSSGKYFEPLNAFKTHKGKLAKLQRRLKNKVKFSQNWQKLKAKIAKLHHKIANCRKDFLHQTSSKISKNHAMIYVEDLQVLNMSKSAKGTAKEHGKNVKQKSGLNRAILDQSWFEFRRQLDYKTQWLGGFLVAVPPQNTSRTCPCCGNTAKENRQTQADFECVECGYTENADVVGALNILEHGRAIVQA
>NZ_CP035368.2|WP_128787155.1|732531_733326_+|tRNA-pseudouridine(38-40)-synthase-TruA
MKIALGIEYNGKQYCGWQRQEKVRSVQEELEKALSFVANEKIEVFCAGRTDSGVHGTGQVVHFETKAVRPEKAWAFGTNANLPDDISVSWAKVVDDEFHARFSATARRYRYILYCNKLRSAILPEGITHCHLELDEEKMHQAGQFLLGENDFSSFRAAQCQSNTPWRNVHHLNVMRKGQYIIVDIQANAFVHHMVRNIVGSLIEVGAGNQPVEWMKWLLEQKDRKLAAPTAKPEGLYLVNVIYPEKFAIPQKNLGPLFLEDNLI
>NZ_CP035368.2|WP_128787156.1|733391_734282_+|acetyl-CoA-carboxylase,-carboxyltransferase-subunit-beta
MSWIDKIFSKGTSSSTSRKANVPEGVWTKCTSCEQVLYGEEVKRNLYVCPKCGHHMRIDARERLLALLDEGSSQELSADLEPKDILKFKDLKKYKDRITAAQKETGEKDALITMTGTLYNMPVVVAASNFSFMGGSMGSVVGSKFVKAAEKAIELNCPFVCFSASGGARMQEALFSLMQMAKTSAVLAKMREKGVPFISVLTDPTLGGVSASFAMLGDVNIAEPKALIGFAGPRVIEQTVREKLPEGFQRSEFLLEKGAIDMIVKRSEMRSTLGNLLSKLTNQPSPFVEVEVVEHE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP035368_1	1.1\|722461\|28\|NZ_CP035368\|PILER-CR	722461-722488	28	CP031730	Stenotrophomonas rhizophila strain GA1 plasmid unnamed1, complete sequence	37208-37235	6	0.786

1. spacer 1.1|722461|28|NZ_CP035368|PILER-CR matches to CP031730 (Stenotrophomonas rhizophila strain GA1 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.786

gcacttttagcggtagcagatatgccgc	CRISPR spacer
gaactttgagcggtagaagatatgcaat	Protospacer
* ***** ******** ******** ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

772749 : 834901

Mannheimia_phage(44.74%)

transposase,tRNA,tail,terminase,lysis,plate,integrase,head,portal,capsid

attL 761448:761465|attR 832600:832617

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
761448:761465	attL	NA	NA	NA	NA
WP_128787176.1\|772749_774081_+\|integrase	integrase arm-type DNA-binding domain-containing protein	A0A1V0E8G8	Vibrio_phage	7.1e-44	28.9
WP_128787177.1\|774061_774229_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_128787178.1\|774228_774744_-	pyrophosphatase	B3GVZ0	Streptococcus_phage	3.7e-25	42.3
WP_128787179.1\|774764_775250_-	hypothetical protein	NA	NA	NA	NA
WP_128787180.1\|775266_777465_-	replication endonuclease	Q94N00	Haemophilus_virus	7.8e-173	44.7
WP_128787181.1\|777472_777781_-	hypothetical protein	NA	NA	NA	NA
WP_128787182.1\|777770_778031_-	hypothetical protein	NA	NA	NA	NA
WP_128788002.1\|778039_778402_-	hypothetical protein	NA	NA	NA	NA
WP_128787183.1\|778417_778678_-	hypothetical protein	NA	NA	NA	NA
WP_128787184.1\|778771_779020_-	ogr/Delta-like zinc finger family protein	NA	NA	NA	NA
WP_128787185.1\|779031_779505_-	hypothetical protein	NA	NA	NA	NA
WP_128787186.1\|779683_780007_-	hypothetical protein	NA	NA	NA	NA
WP_005633752.1\|780224_780380_-	hypothetical protein	NA	NA	NA	NA
WP_128787187.1\|780422_780620_-	hypothetical protein	NA	NA	NA	NA
WP_128787188.1\|780654_780897_+	hypothetical protein	NA	NA	NA	NA
WP_128788003.1\|781042_781693_+	helix-turn-helix domain-containing protein	A0A0M3LPF9	Mannheimia_phage	3.3e-26	37.6
WP_112080615.1\|781805_782525_+	WYL domain-containing protein	NA	NA	NA	NA
WP_128787189.1\|782521_782752_+	excalibur calcium-binding domain-containing protein	Q19UP2	Mannheimia_phage	8.3e-09	43.4
WP_128787190.1\|782754_783423_+	hypothetical protein	NA	NA	NA	NA
WP_128787191.1\|783456_783729_+	hypothetical protein	NA	NA	NA	NA
WP_128787192.1\|783751_784945_-	phage late control D family protein	R9QBT3	Mannheimia_phage	2.2e-105	52.5
WP_128787193.1\|784944_785382_-\|tail	phage tail protein	A0A0M3LQ18	Mannheimia_phage	2.0e-40	57.4
WP_172622004.1\|785381_785543_-	hypothetical protein	NA	NA	NA	NA
WP_005633772.1\|785710_785857_-\|tail	GpE family phage tail protein	E5E3Q0	Burkholderia_phage	2.2e-07	65.0
WP_128787194.1\|785856_786156_-\|tail	phage tail assembly protein	A0A0F7LBN9	Escherichia_phage	2.6e-10	41.8
WP_005633774.1\|786241_786748_-\|tail	phage major tail tube protein	Q19UP8	Mannheimia_phage	3.2e-53	60.1
WP_128787195.1\|786751_787936_-\|tail	phage tail sheath subtilisin-like domain-containing protein	A0A1S6KZY7	Salmonella_phage	7.3e-101	47.9
WP_128787196.1\|788384_788603_-	hypothetical protein	NA	NA	NA	NA
WP_128787197.1\|788653_789499_-	hypothetical protein	F6MIM2	Haemophilus_phage	1.4e-117	72.4
WP_128787198.1\|789555_789675_-	Com family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_128787199.1\|789849_790338_-	enoyl-CoA hydratase	F6MIM0	Haemophilus_phage	2.5e-47	57.4
WP_128787200.1\|790330_791086_-	hypothetical protein	Q94MX9	Haemophilus_virus	8.7e-31	53.2
WP_128787201.1\|791096_792008_-\|tail	tail fiber protein	M1TAS6	Escherichia_phage	5.0e-41	54.4
WP_128787202.1\|792008_792575_-\|tail	phage tail protein I	A0A218M4J3	Erwinia_phage	3.7e-26	37.5
WP_128787203.1\|792567_793482_-\|plate	baseplate J/gp47 family protein	Q19UQ5	Mannheimia_phage	7.7e-74	49.3
WP_118790004.1\|793478_793814_-	GPW/gp25 family protein	Q19UQ6	Mannheimia_phage	2.6e-19	56.6
WP_128787204.1\|793813_794359_-\|plate	phage baseplate assembly protein V	A0A0M3LPY9	Mannheimia_phage	1.5e-40	61.0
WP_128787205.1\|797559_797907_+	hypothetical protein	NA	NA	NA	NA
WP_128787206.1\|797907_798369_-	phage virion morphogenesis protein	Q19UR2	Mannheimia_phage	2.2e-21	42.0
WP_005633794.1\|798368_798839_-\|tail	phage tail protein	E5G6N3	Salmonella_phage	4.3e-28	47.1
WP_128787207.1\|798804_799068_-	hypothetical protein	NA	NA	NA	NA
WP_065245591.1\|799064_799280_-	TraR/DksA family transcriptional regulator	A0A0M3LS11	Mannheimia_phage	1.4e-10	47.9
WP_128788004.1\|799276_799492_-	hypothetical protein	NA	NA	NA	NA
WP_128787208.1\|799454_799805_-	chemotaxis protein	NA	NA	NA	NA
WP_128787209.1\|799789_800308_-	lysozyme	A0A0M3LPQ1	Mannheimia_phage	7.3e-37	46.9
WP_128787210.1\|800300_800522_-\|lysis	lysis protein	NA	NA	NA	NA
WP_128787211.1\|800523_800733_-\|tail	tail protein X	E5G6M9	Salmonella_phage	7.8e-06	39.1
WP_128787212.1\|800732_801239_-\|head	head completion/stabilization protein	A0A0M3LPQ0	Mannheimia_phage	1.3e-33	45.6
WP_128787213.1\|801363_802026_-\|terminase	terminase	Q19US0	Mannheimia_phage	5.4e-45	45.9
WP_128787214.1\|802025_803057_-\|capsid	phage major capsid protein, P2 family	Q19UT3	Mannheimia_phage	9.9e-102	56.1
WP_128787215.1\|803067_803886_-\|capsid	GPO family capsid scaffolding protein	Q19UT4	Mannheimia_phage	1.3e-67	51.1
WP_149785864.1\|804050_805826_+\|terminase	terminase	A0A0M3LRV4	Mannheimia_phage	1.4e-217	65.1
WP_128787217.1\|805835_806846_+\|portal	phage portal protein	Q19UT6	Mannheimia_phage	9.6e-118	60.7
WP_128787218.1\|807528_808107_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_128787220.1\|808645_809935_+	DUF2931 family protein	NA	NA	NA	NA
WP_095176613.1\|810982_811609_+	CadD family cadmium resistance transporter	NA	NA	NA	NA
WP_128787221.1\|811717_811936_-	hypothetical protein	NA	NA	NA	NA
WP_128787222.1\|813115_813652_+	elongation factor P hydroxylase	NA	NA	NA	NA
WP_128787223.1\|813749_814832_+	peptide chain release factor 1	W8EDB3	Pseudomonas_phage	1.3e-08	42.2
WP_005644900.1\|814884_815325_+	RDD family protein	NA	NA	NA	NA
WP_128787224.1\|815324_816203_+	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_126471625.1\|816202_817006_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_128787225.1\|817018_817873_+	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	2.4e-37	35.6
WP_128787226.1\|817939_818887_+	2-hydroxyacid dehydrogenase	M1H9J0	Paramecium_bursaria_Chlorella_virus	2.0e-24	30.8
WP_128787227.1\|818886_820068_+	lipoprotein-releasing ABC transporter permease subunit	NA	NA	NA	NA
WP_014065207.1\|820071_820755_+	lipoprotein-releasing ABC transporter ATP-binding protein LolD	G9BWD6	Planktothrix_phage	1.3e-38	41.0
WP_128787228.1\|820754_822005_+	lipoprotein-releasing ABC transporter permease subunit LolE	NA	NA	NA	NA
WP_128787229.1\|822064_822475_-	DUF1043 family protein	NA	NA	NA	NA
WP_128787230.1\|822564_822915_-	RidA family protein	NA	NA	NA	NA
WP_049355553.1\|823026_823743_+	YwiC-like family protein	NA	NA	NA	NA
WP_049355552.1\|823744_824419_+	sel1 repeat family protein	NA	NA	NA	NA
WP_128787231.1\|824494_825118_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_128787232.1\|825059_825650_+\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	7.2e-57	62.8
WP_149785865.1\|825694_827704_-\|tRNA	bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	NA	NA	NA	NA
WP_126471598.1\|827886_829107_+	beta-ketoacyl-ACP synthase I	NA	NA	NA	NA
WP_049372483.1\|829477_831202_+	acetolactate synthase 3 large subunit	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	3.6e-56	29.4
WP_005695880.1\|831201_831693_+	acetolactate synthase small subunit	NA	NA	NA	NA
WP_128787234.1\|831922_832588_-	DUF484 family protein	NA	NA	NA	NA
WP_128787235.1\|832652_833951_-	adenylosuccinate synthase	W5S5V7	Pithovirus	4.8e-69	36.1
832600:832617	attR	NA	NA	NA	NA
WP_128787122.1\|834082_834553_-\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	5.8e-49	61.9
WP_149785904.1\|834613_834901_-\|transposase	IS3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

1267612 : 1275893

Bacillus_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005696347.1\|1267612_1268260_+	GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.7e-43	44.8
WP_128787484.1\|1268305_1268449_-	hypothetical protein	NA	NA	NA	NA
WP_128787485.1\|1268617_1269304_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	6.0e-55	50.2
WP_049357348.1\|1269296_1269722_+	6-carboxytetrahydropterin synthase QueD	A0A1U9WRB3	Streptococcus_virus	3.0e-20	41.8
WP_128787486.1\|1269727_1270357_+	7-carboxy-7-deazaguanine synthase QueE	A0A1V0DYC7	Dinoroseobacter_phage	4.1e-10	33.6
WP_128787487.1\|1270517_1272416_+	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	5.1e-96	35.9
WP_128787488.1\|1272432_1273626_+	nitrite reductase, copper-containing	NA	NA	NA	NA
WP_128787489.1\|1273637_1275893_+	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	5.7e-86	36.6

DBSCAN-SWA_3

1563910 : 1579232

Vibrio_phage(37.5%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049374949.1\|1563910_1564927_+	nucleoid-associated protein YejK	A0A1V0E8C0	Vibrio_phage	7.3e-65	41.3
WP_126470685.1\|1564996_1565410_+	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_128787682.1\|1565473_1566175_+	response regulator	W8CYM9	Bacillus_phage	2.4e-30	36.2
WP_128787683.1\|1566174_1567578_+	envelope stress sensor histidine kinase CpxA	NA	NA	NA	NA
WP_128787684.1\|1567615_1569784_-	heavy metal translocating P-type ATPase	A0A218MNH6	uncultured_virus	7.7e-189	52.5
WP_049356372.1\|1569770_1569980_-	heavy-metal-associated domain-containing protein	A0A218MNH0	uncultured_virus	6.1e-11	49.3
WP_005699815.1\|1570060_1570447_+	Cu(I)-responsive transcriptional regulator	NA	NA	NA	NA
WP_005696757.1\|1570449_1570767_-	met regulon transcriptional regulator MetJ	NA	NA	NA	NA
WP_128787685.1\|1570898_1571786_-	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	6.2e-60	46.9
WP_128787686.1\|1572008_1572200_-	carbon storage regulator CsrA	A0A2I7RT00	Vibrio_phage	1.9e-11	60.8
WP_128787687.1\|1572278_1574903_-\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	7.9e-79	38.0
WP_014064852.1\|1575090_1575516_-	universal stress protein UspA	NA	NA	NA	NA
WP_128787688.1\|1575620_1576913_-	Xaa-Pro aminopeptidase	NA	NA	NA	NA
WP_128787689.1\|1576925_1577474_-	YecA family protein	NA	NA	NA	NA
WP_005696764.1\|1577585_1579232_-	chaperonin GroEL	A0A2I7SAK5	Vibrio_phage	1.4e-190	68.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage