CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP022593	Mycoplasma bovis strain NADC57 chromosome, complete genome	3 crisprs	NA	1	0	7	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP022593_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022593_1

380438-380544

Orphan

Consensus_repeat	Method
AAGATCAAGGCAACCTAAATCAACAAGATAAAAAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022593_1

>merge|NZ_CP022593|1|380438-380544|CRISPRCasFinder
AAGATCAAGGCAACCTAAATCAACAAGATAAAAATAATGAGGAAAATCAAAAAAATGAATCAATGCCCCACAAAGATCAAGGCAACCTAAATCAACAAGATAAAAAT

>NZ_CP022593|1|1|380438-380544|CRISPRCasFinder
AAGATCAAGGCAACCTAAATCAACAAGATAAAAAT	AATGAGGAAAATCAAAAAAATGAATCAATGCCCCACA
AAGATCAAGGCAACCTAAATCAACAAGATAAAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022593.1\|WP_078086167.1\|377751_379353_+\|IS1634-like-element-ISMbov3-family-transposase	unknown	unknown	gnl\|CDD\|227708
NZ_CP022593.1\|WP_013456078.1\|372422_372830_-\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888
NZ_CP022593.1\|WP_013455983.1\|375320_376283_-\|DNA-polymerase-III-subunit-delta	unknown	unknown	gnl\|CDD\|224383
NZ_CP022593.1\|WP_013456339.1\|383432_384254_-\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|224398
NZ_CP022593.1\|WP_075271112.1\|396547_398797_+\|putative-immunoglobulin-blocking-virulence-protein	unknown	unknown	gnl\|CDD\|275319
NZ_CP022593.1\|WP_013455970.1\|387046_389011_+\|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl\|CDD\|223350
NZ_CP022593.1\|WP_013455979.1\|367868_370601_-\|cation-transporting-P-type-ATPase	unknown	unknown	gnl\|CDD\|223550
NZ_CP022593.1\|WP_115300213.1\|382489_383218_+\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP022593.1\|WP_075271115.1\|391439_394049_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366776
NZ_CP022593.1\|WP_075271114.1\|394123_396352_+\|putative-immunoglobulin-blocking-virulence-protein	unknown	unknown	gnl\|CDD\|275319
NZ_CP022593.1\|WP_075271152.1\|389196_391407_+\|putative-immunoglobulin-blocking-virulence-protein	unknown	unknown	gnl\|CDD\|275319
NZ_CP022593.1\|WP_013456498.1\|385663_386911_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022593.1\|WP_080551570.1\|373698_374727_+\|IS30-like-element-ISMbov1-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP022593.1\|WP_013456269.1\|376466_377525_+\|site-specific-DNA-methyltransferase	unknown	unknown	gnl\|CDD\|334588
NZ_CP022593.1\|WP_013456083.1\|384342_385530_-\|phosphopentomutase	unknown	unknown	gnl\|CDD\|235430
NZ_CP022593.1\|WP_013456635.1\|370975_371863_-\|UTP--glucose-1-phosphate-uridylyltransferase	unknown	unknown	gnl\|CDD\|133021
NZ_CP022593.1\|WP_080551570.1\|381325_382354_+\|IS30-like-element-ISMbov1-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP022593.1\|WP_013456157.1\|372831_373266_-\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
NZ_CP022593.1\|WP_013455924.1\|371864_372197_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380386
NZ_CP022593.1\|WP_013456160.1\|379486_380194_-\|MjaI-family-restriction-endonuclease	unknown	unknown	gnl\|CDD\|370566

Protein	Function_ID	Function_description	E-value
NZ_CP022593.1\|WP_078086167.1\|377751_379353_+\|IS1634-like-element-ISMbov3-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.89494e-18
NZ_CP022593.1\|WP_013456078.1\|372422_372830_-\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	1.79038e-70
NZ_CP022593.1\|WP_013455983.1\|375320_376283_-\|DNA-polymerase-III-subunit-delta	gnl\|CDD\|224383	COG1466, HolA, DNA polymerase III, delta subunit [DNA replication, recombination, and repair].	3.3171e-21
NZ_CP022593.1\|WP_013456339.1\|383432_384254_-\|DNA-binding-protein-WhiA	gnl\|CDD\|224398	COG1481, COG1481, Uncharacterized protein conserved in bacteria [Function unknown].	1.9574e-40
NZ_CP022593.1\|WP_013455970.1\|387046_389011_+\|NAD-dependent-DNA-ligase-LigA	gnl\|CDD\|223350	COG0272, Lig, NAD-dependent DNA ligase (contains BRCT domain type II) [DNA replication, recombination, and repair].	0
NZ_CP022593.1\|WP_013455979.1\|367868_370601_-\|cation-transporting-P-type-ATPase	gnl\|CDD\|223550	COG0474, MgtA, Cation transport ATPase [Inorganic ion transport and metabolism].	0
NZ_CP022593.1\|WP_115300213.1\|382489_383218_+\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	1.26398e-50
NZ_CP022593.1\|WP_075271115.1\|391439_394049_+\|hypothetical-protein	gnl\|CDD\|366776	pfam01732, DUF31, Putative peptidase (DUF31). This domain has no known function. It is found in various hypothetical proteins and putative lipoproteins from mycoplasmas. It appears to be related to the superfamily of trypsin peptidases and so may have a peptidase function.	1.79194e-50
NZ_CP022593.1\|WP_075271114.1\|394123_396352_+\|putative-immunoglobulin-blocking-virulence-protein	gnl\|CDD\|275319	TIGR04526, predic_Ig_block, putative immunoglobulin-blocking virulence protein. Members of this family are putative virulence proteins of Mycoplasma and Ureaplasma species. Members share a region of sequence similarity (see TIGR04524) with protein M, a Mycoplasma genitalium protein that binds a conserved light chain region of IgG and blocks its protective function of antigen-specific binding. The seed alignment for this model includes an N-terminal signal-anchor domain and a proline-rich linker domain, and a C-terminal extension, in addition to the protein M-like domain recognized by TIGR04524. [Cellular processes, Pathogenesis].	0
NZ_CP022593.1\|WP_075271152.1\|389196_391407_+\|putative-immunoglobulin-blocking-virulence-protein	gnl\|CDD\|275319	TIGR04526, predic_Ig_block, putative immunoglobulin-blocking virulence protein. Members of this family are putative virulence proteins of Mycoplasma and Ureaplasma species. Members share a region of sequence similarity (see TIGR04524) with protein M, a Mycoplasma genitalium protein that binds a conserved light chain region of IgG and blocks its protective function of antigen-specific binding. The seed alignment for this model includes an N-terminal signal-anchor domain and a proline-rich linker domain, and a C-terminal extension, in addition to the protein M-like domain recognized by TIGR04524. [Cellular processes, Pathogenesis].	0
NZ_CP022593.1\|WP_075271112.1\|396547_398797_+\|putative-immunoglobulin-blocking-virulence-protein	gnl\|CDD\|275319	TIGR04526, predic_Ig_block, putative immunoglobulin-blocking virulence protein. Members of this family are putative virulence proteins of Mycoplasma and Ureaplasma species. Members share a region of sequence similarity (see TIGR04524) with protein M, a Mycoplasma genitalium protein that binds a conserved light chain region of IgG and blocks its protective function of antigen-specific binding. The seed alignment for this model includes an N-terminal signal-anchor domain and a proline-rich linker domain, and a C-terminal extension, in addition to the protein M-like domain recognized by TIGR04524. [Cellular processes, Pathogenesis].	0
NZ_CP022593.1\|WP_080551570.1\|373698_374727_+\|IS30-like-element-ISMbov1-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	9.23257e-27
NZ_CP022593.1\|WP_013456269.1\|376466_377525_+\|site-specific-DNA-methyltransferase	gnl\|CDD\|334588	pfam01555, N6_N4_Mtase, DNA methylase. Members of this family are DNA methylases. The family contains both N-4 cytosine-specific DNA methylases and N-6 Adenine-specific DNA methylases.	1.0519e-31
NZ_CP022593.1\|WP_013456083.1\|384342_385530_-\|phosphopentomutase	gnl\|CDD\|235430	PRK05362, PRK05362, phosphopentomutase; Provisional.	0
NZ_CP022593.1\|WP_013456635.1\|370975_371863_-\|UTP--glucose-1-phosphate-uridylyltransferase	gnl\|CDD\|133021	cd02541, UGPase_prokaryotic, Prokaryotic UGPase catalyses the synthesis of UDP-glucose. Prokaryotic UDP-Glucose Pyrophosphorylase (UGPase) catalyzes a reversible production of UDP-Glucose and pyrophosphate (PPi) from glucose-1-phosphate and UTP. UDP-glucose plays pivotal roles in galactose utilization, in glycogen synthesis, and in the synthesis of the carbohydrate moieties of glycolipids , glycoproteins , and proteoglycans. UGPase is found in both prokaryotes and eukaryotes, although prokaryotic and eukaryotic forms of UGPase catalyze the same reaction, they share low sequence similarity.	5.35032e-119
NZ_CP022593.1\|WP_080551570.1\|381325_382354_+\|IS30-like-element-ISMbov1-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	9.23257e-27
NZ_CP022593.1\|WP_013456157.1\|372831_373266_-\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	3.78069e-82
NZ_CP022593.1\|WP_013455924.1\|371864_372197_-\|hypothetical-protein	gnl\|CDD\|380386	cd06981, cupin_reut_a1446, Cupriavidus pinatubonensis reut_a1446 and related proteins, cupin domain. This family includes bacterial and some eukaryotic proteins homologous to reut_a1446, a Cupriavidus pinatubonensis protein of unknown function that may be related to mannose-6-phosphate isomerase. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	4.68782e-17
NZ_CP022593.1\|WP_013456160.1\|379486_380194_-\|MjaI-family-restriction-endonuclease	gnl\|CDD\|370566	pfam09568, RE_MjaI, MjaI restriction endonuclease. This family includes the MjaI (recognizes CTAG but cleavage site unknown) restriction endonuclease.	3.88844e-32

>NZ_CP022593.1|WP_013456160.1|379486_380194_-|MjaI-family-restriction-endonuclease
MKTKQNDDFRYEAIIQNSECLEKINFPKYFSPIVNLANQFTKATSPKNVGQLSELFKQYESYIKSQSSNLIPSVRNWEEYYETAVIEYGFSKDEAVDNAINKIFSMLKNFQNMLNSYDEQSLKNDVGVWVKKLMFEKTFTGLSVQKLIVEHIIKLTGCNYIWRLSTASEESLNIDAFINGKPIQIKPISYEHKKITKAIENIQIPIIEYNLNKNDGNIKIIVSNIKELKDYLKSK
>NZ_CP022593.1|WP_078086167.1|377751_379353_+|IS1634-like-element-ISMbov3-family-transposase
MSIGVPRPDNKGFVYRLGYGYLHELKQYHDDPLTIIKAIIANFPLSWTKEQARTKLDEIIKEKKETKKEVLERFKGYEVVEKLFDYFNIFNDCSPTKSTTLKDVVLQLIYQRIKNPISVFNTYMTAKKEKIDTYSKNSFYRSLDYIAKNKDEILRNLNAKICANTNRKIDVLWFDATTTYFETFSREGYKKPGYSKDGKFKEDQIVIGMATDKNEIPLHYKIFPGNVTDSNTFIPFMLEIADIYEVNSVTIIADKGMSVNRNIRFLESKNWKYIISYRMKAGSKQFKEYVLDEKDYVNDGGLIYKTRDIASSYNKKRINGHFRRQIISFSQKRATKDKNDRDILIQNFTKKMNKDNLVSCDDLAGSKKYRFFKPINKGAFYELDIEKIQEDQKYDGYYVYETNRTDLSVKEVINLYSKQWQIESNFKTLKGKLSLRPMYLSTWNHIVGYICLCFISLVFLNYIIYILNSKLGLTGKSKITEHKVINVIKEVKEIEVFVNKQKIETIQVYNDELQESWQTYQILLELLTKEKVT
>NZ_CP022593.1|WP_013456269.1|376466_377525_+|site-specific-DNA-methyltransferase
MHTKHTILNIDALKMNSHIDDESVDLVITSPPYPMIKMWDEIFEINENEIKTEADVNSAFLKATQFLNNIWEKVDKSIKPGGIVCINIGDATRNLGGNFRLFSNSGQVINFFIKKGYLQLPSIIWRKQTNAPNKFMGSGMLPAGAYATLEHEWILIFRKGITKREFKNAKDKSLRNESAFFWEERNVWFSDLWDFKGIKQKNDIKNSRDRTAAYPIELPYRLISMFSVKNDIVFDPFLGTGTTTLASMLLQRNSIGVEIDKSLCNHFKEYLVKNDVKLVDNFNDKISKRISSHTEFVKKRVNEGKLLKHYNSILGTEVMTSQEKFISFNKVSSINKIDDKTFEVIYKTLQSE
>NZ_CP022593.1|WP_013455983.1|375320_376283_-|DNA-polymerase-III-subunit-delta
MIFIYGPEKFLIEQEVQRIRKEHNDKVLEIFRFDDQASINDLISSASSNNLFTGSKLFLIYALPFFDKSILKDDLKNADDLINAINVNNQDIFVFINENIISKDKISVNSWTKFIFENNNHEVTMIEAKEISESKLFSLAKSLANKHKLHIDDEAIKLLINKVNNDTLMLSAEIIKLSNLEKHISAEVIENSTDTMLGDDVFAFSNALETNDLGIIWSKYKEKMLEGTEISALIGQISQIFIIAHQIYAYKVCHLSIDQLSRDLKLNSYRIKKISYFLSKIGINKIKKMILSLSKLDKDIKNGLISEKIGFERFLITFFN
>NZ_CP022593.1|WP_080551570.1|373698_374727_+|IS30-like-element-ISMbov1-family-transposase
MKTVSNIVGFKSRSIYNLFDRITIETKRGYAKYQKKCKLCGMDLKGKTIYVISALKFLNLIETRHDSKRLENNSKLLMKYIEIFKFYKQLLYFYLKNRNSFNLDSKAVKQSVASIIFKYIRELEAQGKLQNSYIPSVQNFYRILAKHSAFGLKLDILPYKSNGKYGSRTTVKHETKKKTIGKLITERPESVNLRLNDNDYEMDTVIGLRSDNYCILTLINRKSRMFYCTLSRRNAKAIKENLEKLIKDNNLVIDTLTIDNGSENYKLPEIESIKEIFHCHPYSSSEKGSIENAHRLLRRYIPKGKSIDKYVGQDLKPIADFINSHPRIYKGVSGFKCAKQMQ
>NZ_CP022593.1|WP_013456157.1|372831_373266_-|50S-ribosomal-protein-L13
MRQTTIVNREKANKKWFVVDAENQVVGRLAAFVASVLRGKTKPTFTPNADMGDYVIIINAEKAIFTAKKEEDKVYYHHSGYPGGLKSITAAKLRAKKPTAIVEKAIHGMLPHTKLGNKQRRNLFVVAGPEHKYAAQKPERLEVR
>NZ_CP022593.1|WP_013456078.1|372422_372830_-|30S-ribosomal-protein-S9
MAKSNSSMIEYRGLGRRKSSTARVILRPGSGKFTINNREAKNYLLSDLHIQDAEQPLVLTETKGQFDILVNVRGGGLKGQAGAIRLGIARALLLASDTYRAKLKPAGMLTRDARSVERKKPGLNKARRARQFSKR
>NZ_CP022593.1|WP_013455924.1|371864_372197_-|hypothetical-protein
MDNNVKLINNIYSNNLIKPILGCEKFYNIAQLGNSNIELIYSNSASTDWLINNDHDEVAILVQGSASLLDDSHKKINMQAGDCLFVKKNSRHKILSTSADAIWISIHNKE
>NZ_CP022593.1|WP_013456635.1|370975_371863_-|UTP--glucose-1-phosphate-uridylyltransferase
MNKKVRKLIIPAAGWGTRFLPMTKVVHKELLPILDTPLISLLVDEAIEAGIEEIILIISERKKDIANYFAVNKELETELESKNKLSLLKKVKSTNKEGLIKIVIQHSQNGLGHALACAKNVIKDEPFAIILGDDLIKSKVPAIKQLIEFYYKTGSNILGVQSVSDSDIPKYGIVAPIDENEKSTNFFKIKGAVEKPKLSEAPSNKAILGRYVFNSEILDILSKIEYDGSNEIQVVDAFEKLQNEYKQDIYAFVFEGTRYDLGSVKGFVQANIDYALDNIELKDELTEFINEKLSE
>NZ_CP022593.1|WP_013455979.1|367868_370601_-|cation-transporting-P-type-ATPase
MKWDEAQKFNGLSDEQVAINLQKYGENTLTKSKKINPIVAYFKQFIDPMVILLIIAAIISVSLAIFEHIKGSRNSTQIIIGYVEPAIIMLVILLNSAIGAYQEVKSDQAVRALENKTISNSTVIRNNEVQNIPANMLVVGDLVLLSAGDTINADGRIVNASNFYVVESSLTGESEAVLKTTNWNATDDKTLAENKHLVYSGTFVSNGKASYIVESVGKETQIGKINSSLQNQKKNLSPLQTKLNKLSKWFGYSGIILLFISMLLQIVFNNVSSGSWTNPDVYTNSLITGISLAVAAIPEGLIAFTTVILSIGVSKISKEKGLVKNLLAVETLGSANIICTDKTGTLTENKMTVVDLYLNKKGFLDKIDVNRNEFNELLNSLCFCNDAYLTIDNEEIKEIGDPTETGLLLFALKHSVTKQELLKTNNIIHTLPFDSDRKMMSVLVKDNKSDKIMITKGAPDVVITKCNNIDKDEVMQINNDWAAKSYRVLAFAKKTVNHNSIDFKDEEDLEFIGLVAMIDPPRANVAKSVLEAQNAGIKVVMITGDNLITAKSIATNLGIYDPNGDDICLDGSELKDWDDDKLRNNVQKIAVYSRVNPSDKLRIVKAWQSYDKVVAMTGDGVNDAPALKASDIGCAMGITGTDVAKQSADFILTDDNFNTIVRSVKNGRQIYDKVKTVIMNLLISSVTEVIVMLIGLIAFYYAFKNYFSDSEFYVFSASQLLWINLLTHGLPAIALGIIDSEVDVMHRPPYSKSESIFARGMGINLLWQALVISLVSLLSYTAGALYTIRFYSGLNLLTIASTCAFVTMGIATSINAINLINNNSIFKANIKKYWPVFAAISFSSLFVILVAFVPNLAKVFRMYEHLLTFHNGILLSWSLPLAFVNTICFEIKKLIVNTKTNRTSVLSVSY
>NZ_CP022593.1|WP_080551570.1|381325_382354_+|IS30-like-element-ISMbov1-family-transposase
MKTVSNIVGFKSRSIYNLFDRITIETKRGYAKYQKKCKLCGMDLKGKTIYVISALKFLNLIETRHDSKRLENNSKLLMKYIEIFKFYKQLLYFYLKNRNSFNLDSKAVKQSVASIIFKYIRELEAQGKLQNSYIPSVQNFYRILAKHSAFGLKLDILPYKSNGKYGSRTTVKHETKKKTIGKLITERPESVNLRLNDNDYEMDTVIGLRSDNYCILTLINRKSRMFYCTLSRRNAKAIKENLEKLIKDNNLVIDTLTIDNGSENYKLPEIESIKEIFHCHPYSSSEKGSIENAHRLLRRYIPKGKSIDKYVGQDLKPIADFINSHPRIYKGVSGFKCAKQMQ
>NZ_CP022593.1|WP_115300213.1|382489_383218_+|BspA-family-leucine-rich-repeat-surface-protein
MLFNLRIYTDGKFSSLKDKNQNVVITQIGYSLKDKSSKREKVIEIHKMPKNTKEVPEHLPLKIKSLKLAFNELNSEEVLNLDKWDVSNVESMETMFFDAKKFNQDISKWKTKNVTNMTGLFSGAHNFNKPLNLWNVSKVTTMTNMFDGASKFNQDLNDWDVSKVINMEEMFRSAESFNGKIGDWNVENVETLDDMFLYATKFQQDLSEWKTKKVKSKRWDFIFNHTYEYKSKVLKAWMENNK
>NZ_CP022593.1|WP_013456339.1|383432_384254_-|DNA-binding-protein-WhiA
MNFTKEIKLEILSKKRNIDDASEFLRGYIYSKCIIDNDIIKLRIYDKSTKSTVLKSLNKIGIKYENKNTVILINKDNFSLIEDFSYPSSFFQGVFAGNGSISNLNNSSYHLQLASNYEEFIDIIINKLNEYDFNFVKIKHNNKFIAYIKKHEKISDFLKAISVTSSFFNFMDNTISRDFLNNTNRLRNIDASNINKIVTASNKYIKNIDLMYELELENKFNDDQLKLFQIMKENPNESLSSIADLYAYKENKSISKSGIYHWLKKLEKTVMKK
>NZ_CP022593.1|WP_013456083.1|384342_385530_-|phosphopentomutase
MAKFKRIFMIVTDGLGIGPDKDQKKFGDAGANTLYSASLSSMFFIDTWKKLGIGNVAQLEGNYHVKSPLAYVSRIQEVSNAKDTLAGHWEMMGIKTEVPFPTFTETGFPEDLITELEKAFDNRKIICNKAGSGTEIIDQYAEEQKQNGSIIVYTSNDSVLQIAAHEEWIGLENLYRYGKAAREICSSKPEWNVGRIIVRPFVGEDGKYTRTFNRHDYANAPEPMILNKLQEAGIEVIAIGKINDIFVGQGISRAIHSSGDADGMDKAIELAQLDEENKFIFVNLVQFDSHYGHRRDVDGFASNVATLDSKLGKLIQVMKKDDLLIMTSDHGNDPAYPGFNHTREMLPLTIYSKLFKEPRVLNDVTGLGTTGNIVARNFGVETVSLTGEDIFDKLV
>NZ_CP022593.1|WP_013456498.1|385663_386911_-|hypothetical-protein
MSNFNLILSREKFNHQQYASVKGIVKSKLNEYYSDKKNSRKINLATVGIYTSIPLFIIGAILLLSSITISFVVIFKTGKNEWLLNPDHFRPLLASLYSLSFVFLIAWCILYPIALRARIFLKKDIVASVNNRDLTDHLLDYINLKPRYENDENGNKIVNFGHISFFKNTSNFKNLSKFNVINNKYEMYEALSNKQFIKMQNIEYRNEEWLAINNLSNKEIKRLKKAKAKVYKGKIQRIEHNLYFGIATKLLNLNKSVSVTLFDEFNNYTPESFKKLDVKDEFSILNISSEDTELMQKWANDISNLSYLNDLKNEFDSIAINSSISLKNSRRDKSFAKDLSIFIKNQEAFIWFKTPTQLLDLSFKSPTLNKDEITELIVNKILDEFYLVYLSLMFLAPFGYDNVVSIDENETIVNQ
>NZ_CP022593.1|WP_013455970.1|387046_389011_+|NAD-dependent-DNA-ligase-LigA
MESKNAKELIKSLVDKINQWNYEYYQLNKPSVSDLEYDKALWELEKLEKEYPEFVLDDSPTFKLGSFASEKFTKFIHKKPMLSLAKAYSYDDIKSFINNISKIVPAERINFNIEPKVDGLSIALHYKKGKLVKAVTRGDGTEGEDVTENIYQIKSIPKLINYLNDLEVRGEVFISKDNFKKINESNNFANARNAASGTLRQLDSTIVAKRNLSAFLYEVVEPEMHNINYQNEALEFMKKLNIPTNPFSKVVEIEELEEAISDFAEIKNKLDYDSDGLVIKLNDLQMWEKLGKTSKFPKHSIAFKYDVEVASSTIVDILTSVGRTGKITYIANIHPVILNQTSVRAATLHNHNFIKDMNININDEVNIIKAGEIIPKVISLKNSKNYVDYYKKATNCPSCNSELIEFEGIVDQFCTNDECPEKNVNNIYHFASRNCMNIVGLGLSTVKDFYPKFIKKIKDIFSLYKYKSELILLPRYGEQKVDNILNSIESVKNKAFSKVLFALGIKHIGQRAAKLISDNYVNFAEILNDSELSKLKSTKNIGPKIIESLTEYINNPLNKDLLIYLDSIFNYEGKTKAISNIFSGYSFVITGTLSEPRSHFVKIIEENSGSVSASVSGRTSYVLAGSEAGSKLEKAYKLGVKVINEEQFYKLLEH
>NZ_CP022593.1|WP_075271152.1|389196_391407_+|putative-immunoglobulin-blocking-virulence-protein
MNLFRKKKNRVIILSLATGAVISASTGAFVYSSNSDSNLSKLLFNNSRDAELASNKNNISKSTDSIKDNNVIENTKPIAPKPVEEKVINVPDTTTENSSAPEVNRNTVTPERSEPLIAKPNVVTKQISIHGVIVNATIEVVPDRHISDYDKNKGISNINPYQNIIVSKVLNVEVTKELIDKSVSNALDGKDGTGLFAGTFFKTLENIFKSSSDLATAEEVVKQNMSVYRDNIHRYEKLLNSPNVINFLTEEGKQKYPTMKFDSPIQRNIWLINHLDKTKFTKLAKDAEAFLSQGLAISGRSAIINEDGTLSSLAFAPDDQFNTVTSRVSRDNRERRVFGYDSPYGRSPDSVWEGSYQGWNKEDVTDKPEYSRYNVSSADGIKLTKLTREKTDNSPGALNEGLVVEIDASNVSGYGKTLDLINKLKNDKVQVTSYRIKNMGSNDPSQAFKKILSALPDKIPQLELFFSAEATNNSSLIALENKHIKELSLYTLGNSLLHKWSFNPLALRKTEWINTVDYNVSRDFLPNTAIPTRITFDTIAFDKEDFKDKSFDRINDGLRMVYFARNNEPFFQAGLGPGLNPDHNEGNNSYPVGIDFSRIEGIKSLRNLVFNDVVNPNNTPRKIRRLTLFNNKPSFEISSDELTHASFEHFATDAMDRFSKPKIMFSNGDVTVSIRISDSNTLDSKAIWNLSKFFEYNEKLKSTKSIKVPENASALKEQLTKLGYRVESSDGNITYT
>NZ_CP022593.1|WP_075271115.1|391439_394049_+|hypothetical-protein
MRITKKLLLISSSASLFSSLLIAAKCNNDSSKNKSNDDKKIGLLSDDQFEKLINNTNNLNDIAQLTFSSNFGQSKSLDKTLPTEIEENPGNLKISVNNKYSDSITVTVNGAKTDKDASRNISNIKGEVSVYVGFKNKSTGKEIYKNFILKGLARNPVGADHNGRLSGDPLAAIGGQQGYLDYHKKTQTERFEKDNNEYVNRLKGMLSRDGGKEVDFKTFMGIKTTEEQIKKFNETAKLVNFDSYENAALKGFTIPVYENGSTSNPKLKVYDAPEVPKGPSPIDTIGRNIYRSNGLARTLLNETYKTIAEQTFQVSFTTLKDFEDEIKEAEKLKEDSKKWTTEQFQQFTFKDRAALKANYETNLYKLELEIKSQSPEALRGLEQSFAERKKKLKENYEAEDARLEKLDSSELAKEMDKRIAEYNKLKEEKRTYSSVSGTMWIMDFMLPENSGKGATKFYFGTNSHVAKGLTNKTTKFSVSRLNENVGVGSHFRLNDLDDRFTRFSFDNVEKDAINVIFQATDFLDSKPSDFLESSQKAKFGDVEEFMDFAVIEIDFEKILENKTKNFSAISNNKNHSSNYLNKSTEDIVKLITNNYESKKDKHIKFRSESYLKDYSKIDRPIILDTKKKEEVKKFNDLDSLYILGYPSATGDYFLENYIDEDQQKVVKTNFSMWINADEKYYKNVSAQEGAPSNHPKENLERGEFLSYEIGYRSFIDKPGLTDGFLAASRTGNDLYTINGKKYFNYGLHIMPRSYVPYGGASGSSVRNKNNELIAVFHTANNSAKTGLAATFRSYGYDYKGLFGDYKLPAYDLIYGGAPGQKNSYRDALEKKYKKNGKQYKTNLFQKGFSKDQIPQQFKFNETSSTTVDK
>NZ_CP022593.1|WP_075271114.1|394123_396352_+|putative-immunoglobulin-blocking-virulence-protein
MKILKTKKNKILMFSLLSGGIVSVAAGAAIYKASSDFDLAKSIFSSDSFDSELANSNNVKHTNDSIRDKNVTEKAVEPIKVEKPKIEPIIVKTPKAEESATIEPPKEAPKPVESQPIIASPTTERRKININGVEVYAIVEVTPDRKVTEYDIKKGIANRDPYQSTIVNKLVSVEVTDQLRKSTVNKALTSGDGEGLFDGTFFKVINDLINVDKDSLDIAEGVLKQNSQIWENNLFRYKELLDSDKVVNFLMPGKDVEYKDIVKKGGFKTPNQRYIWLIANLDKSKFTKLASKSDKYLNEGLVVSPRNAKINANGEIDAHAWSPSPEFNTVTSRYSRDNRLKRVFGYNSHFWRSPADTEEGNYPGWNKTDATSEFKEYGASESDGITVHKLERIEKIKEEDGQINEGYVVNIDAKNPAGYSKTKKLIEDLKKSGKKITSYRIKNMGEADPAQKFKEILAALPDDLPQLELFFSANATNTSSLIALENKKIKELSLYTLGNSLLQKWSFNPWAFKKTAWINTNDYNVSYEYGRNKPLATRITFDTIAFDQDDYKGDNNFERINDGLRLVYYARNNERAFQGSFGPGLNPDNAEGNNSYPLGLDFSRVPNIKSLRGLEFHDSQNPSNKARKIKRLTLFNNSATFEITSNELNQASFHHIMEPVPGDSDKPKIMFSNGDITNSIKISSKEKLSPDGLTNLNKFFQLNDALKASKKIIVPKDASELISQLQGAGFNVEAGTESIIYT
>NZ_CP022593.1|WP_075271112.1|396547_398797_+|putative-immunoglobulin-blocking-virulence-protein
MSIFKKKKSRILLISLSAGIVVSVSSGALIYNASSDNSLSKLLFSSESDSLLHPSSSVDYSKTVNSITDKNVKELSKQPKVIEKPVEKIEKITPPKIEVKPEEPAATPEPPRITPEIPNYKPDVTSLIQRTEKISIFGVEVNATVLARPDRVVSEADKSRGITNVNPYQNVTVSKLLNIEVTQELENKVIQNALGSEEGQGLGLFSNNLFKIADSIGTKDGLDKAEDVLVRQNPGTWGEQIHRYKALINSGKFKDFLKEGKLEEYERLVKENSFKTANQKYLWIIINLDKSKFTKISQNSLNYLKQGLAIDPRNAIINANGEIDSLVWNVPNQYNTVTSRLSRDNSTRRAFDYDEWYLRSSDSIVDGKFPGWTKNDKTSEYSSTYNIQPNDGIKVFELTRDKPVNDGSKRNSGIVVEIDAANSSGYNKIKELIEKFKANNKEITSYRIFNMGVTSPSQEFKDILKSLPDKLPQLELFFSAQATNTSSLIALKDKNIKELSLYTMGNSLLDSWSFNPWSLNKVEWINTNDYNVSAQYPPNTPIATRISFDTVAFDQEDYSKVGDWERINNGLRMVYFVRNNEPFFQGRHGQGTEPDSSESGNSYPTGLDFSRVPTIKSLRGLVFHDIEKPNNGSRKIKRLTLANSGDSFEISSDELSAAGLENLAIGELEQPKIFFSNGQETKAIKIKLESGKKELDSSAIENLRKFYAYSDSLKVGGKSIKVDSDATELKQQLTGLGYKVEEDNGLKFT

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Crispr_ID: NZ_CP022593_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022593_2

566863-566969

Orphan

Consensus_repeat	Method
CATCGCCAATGAAGTCTGAGCCTGTAGAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022593_2

>merge|NZ_CP022593|2|566863-566969|CRISPRCasFinder
CATCGCCAATGAAGTCTGAGCCTGTAGATATGGATGAATTAAAATTAAATGATGGGAATAAGATGATGGATGATAATCCATCACCAATGAAGTCTGAGCCTGTAGAT

>NZ_CP022593|2|2|566863-566969|CRISPRCasFinder
CATCGCCAATGAAGTCTGAGCCTGTAGAT	ATGGATGAATTAAAATTAAATGATGGGAATAAGATGATGGATGATAATC
CATCACCAATGAAGTCTGAGCCTGTAGAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022593.1\|WP_013455921.1\|575581_576313_+\|DNA-processing-protein-DprA	unknown	unknown	gnl\|CDD\|223829
NZ_CP022593.1\|WP_115266416.1\|578635_581614_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|274008
NZ_CP022593.1\|WP_174245827.1\|554494_556096_+\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NZ_CP022593.1\|WP_013456453.1\|558358_560530_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366776
NZ_CP022593.1\|WP_115266510.1\|570313_571342_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP022593.1\|WP_013456319.1\|565911_566640_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|350157
NZ_CP022593.1\|WP_013456130.1\|556292_556682_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022593.1\|WP_115300219.1\|569153_569930_+\|variable-surface-lipoprotein	unknown	unknown	unknown
NZ_CP022593.1\|WP_013456187.1\|561531_561972_-\|Holliday-junction-resolvase-RuvX	unknown	unknown	gnl\|CDD\|335420
NZ_CP022593.1\|WP_013456554.1\|557461_558184_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|226674
NZ_CP022593.1\|WP_013456567.1\|573421_574006_-\|variable-surface-lipoprotein	unknown	unknown	unknown
NZ_CP022593.1\|WP_115266415.1\|577230_578583_+\|YitT-family-protein	unknown	unknown	gnl\|CDD\|224203
NZ_CP022593.1\|WP_115266414.1\|576299_577136_-\|HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|369792
NZ_CP022593.1\|WP_013456004.1\|581687_582362_-\|ribonuclease-III	unknown	unknown	gnl\|CDD\|274024
NZ_CP022593.1\|WP_013456305.1\|560813_561542_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022593.1\|WP_013456478.1\|574316_575357_-\|zinc-dependent-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|176257
NZ_CP022593.1\|WP_013456137.1\|561964_564607_-\|alanine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234701
NZ_CP022593.1\|WP_013455944.1\|564617_565742_-\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664
NZ_CP022593.1\|WP_115266511.1\|572208_573219_-\|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl\|CDD\|176257
NZ_CP022593.1\|WP_013455952.1\|556684_557137_-\|SocA-family-protein	unknown	unknown	gnl\|CDD\|226128

Protein	Function_ID	Function_description	E-value
NZ_CP022593.1\|WP_013455921.1\|575581_576313_+\|DNA-processing-protein-DprA	gnl\|CDD\|223829	COG0758, Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion].	5.818e-26
NZ_CP022593.1\|WP_115266416.1\|578635_581614_-\|AAA-family-ATPase	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	3.3225e-97
NZ_CP022593.1\|WP_174245827.1\|554494_556096_+\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	3.36377e-19
NZ_CP022593.1\|WP_013456453.1\|558358_560530_-\|hypothetical-protein	gnl\|CDD\|366776	pfam01732, DUF31, Putative peptidase (DUF31). This domain has no known function. It is found in various hypothetical proteins and putative lipoproteins from mycoplasmas. It appears to be related to the superfamily of trypsin peptidases and so may have a peptidase function.	9.88032e-28
NZ_CP022593.1\|WP_115266510.1\|570313_571342_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	8.93761e-27
NZ_CP022593.1\|WP_013456319.1\|565911_566640_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|350157	cd09006, PNP_EcPNPI-like, purine nucleoside phosphorylases similar to Escherichia coli PNP-I (DeoD) and Trichomonas vaginalis PNP. Escherichia coli purine nucleoside phosphorylase (PNP)-I (or DeoD) accepts both 6-oxo and 6-amino purine nucleosides as substrates. Trichomonas vaginalis PNP has broad substrate specificity, having phosphorolytic catalytic activity with adenosine, inosine, and guanosine (with adenosine as the preferred substrate). This subfamily belongs to the nucleoside phosphorylase-I (NP-I) family, whose members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases, such as purine nucleoside phosphorylase (PNPs, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases, such as AMP nucleosidase (AMN, EC 3.2.2.4), and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	2.39285e-106
NZ_CP022593.1\|WP_013456187.1\|561531_561972_-\|Holliday-junction-resolvase-RuvX	gnl\|CDD\|335420	pfam03652, RuvX, Holliday junction resolvase. This family of nucleases resolves the Holliday junction intermediates in genetic recombination.	2.97833e-47
NZ_CP022593.1\|WP_013456137.1\|561964_564607_-\|alanine--tRNA-ligase	gnl\|CDD\|234701	PRK00252, alaS, alanyl-tRNA synthetase; Reviewed.	0
NZ_CP022593.1\|WP_013456554.1\|557461_558184_-\|SDR-family-oxidoreductase	gnl\|CDD\|226674	COG4221, COG4221, Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only].	1.0957e-80
NZ_CP022593.1\|WP_115266414.1\|576299_577136_-\|HAD-IIB-family-hydrolase	gnl\|CDD\|369792	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase. This family contains haloacid dehalogenase-like hydrolase enzymes.	7.22901e-41
NZ_CP022593.1\|WP_115266415.1\|577230_578583_+\|YitT-family-protein	gnl\|CDD\|224203	COG1284, COG1284, Uncharacterized conserved protein [Function unknown].	5.58775e-29
NZ_CP022593.1\|WP_013456004.1\|581687_582362_-\|ribonuclease-III	gnl\|CDD\|274024	TIGR02191, Ribonuclease_3, ribonuclease III, bacterial. This family consists of bacterial examples of ribonuclease III. This enzyme cleaves double-stranded rRNA. It is involved in processing ribosomal RNA precursors. It is found even in minimal genones such as Mycoplasma genitalium and Buchnera aphidicola, and in some cases has been shown to be an essential gene. These bacterial proteins contain a double-stranded RNA binding motif (pfam00035) and a ribonuclease III domain (pfam00636). Eukaryotic homologs tend to be much longer proteins with additional domains, localized to the nucleus, and not included in this family. [Transcription, RNA processing].	9.29408e-60
NZ_CP022593.1\|WP_013455952.1\|556684_557137_-\|SocA-family-protein	gnl\|CDD\|226128	COG3600, GepA, Uncharacterized phage-associated protein [Function unknown].	1.41952e-29
NZ_CP022593.1\|WP_013456478.1\|574316_575357_-\|zinc-dependent-alcohol-dehydrogenase	gnl\|CDD\|176257	cd08297, CAD3, Cinnamyl alcohol dehydrogenases (CAD). These alcohol dehydrogenases are related to the cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Cinnamyl alcohol dehydrogenases (CAD) reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.19893e-159
NZ_CP022593.1\|WP_013455944.1\|564617_565742_-\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
NZ_CP022593.1\|WP_115266511.1\|572208_573219_-\|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl\|CDD\|176257	cd08297, CAD3, Cinnamyl alcohol dehydrogenases (CAD). These alcohol dehydrogenases are related to the cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Cinnamyl alcohol dehydrogenases (CAD) reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	8.82214e-146

>NZ_CP022593.1|WP_013456319.1|565911_566640_+|purine-nucleoside-phosphorylase
MPTPHLSCNKGEIAKIVLMPGDPLRAEYMAKKFLTNPKLVSLVRNIYFYTGEYKGKLVTIGASGMGVASMGIYAYELFTEYDVDVIIRLGSTGSYVDNLDVKQPVLVKRAYADGLGFVSLMTGEKTHNAYPDKEIVKLLKRSAKKKKINVLDVSCHTTDVFYSIRSLEETINKTKCQVVDNECFGLFTTAKRCNKKAAALLSVSENIVTGKSMTSDERLLEFSQMFEVALNALDNIYKHIEN
>NZ_CP022593.1|WP_013455944.1|564617_565742_-|tRNA-2-thiouridine(34)-synthase-MnmA
MSNKKKVILGMSGGVDSSVCAYLLLKQGYEVEGLFMRNWDSMLNNDFLGNENISQDICPQEQDYHDALEVANKLGIKLHRVDFVNEYWNDVFKTFISEYEAGRTPNPDILCNKYIKFKAFSDYAFNNLGADYIAMGHYAKVTDGRLYRAKDQNKDQTYFLAQLSHEQLKRVLMPLAEFNSKEEVRKIAQEQGLITASKKDSTGICFIGERKFTKFLQNYIPMQPGDIVDIRTNNKLGKHEGCFYYTIGQRKGLNLGGQAEPYYVCGHDVKKNILYVAPSSDLSYLTSDALLATGLTLNHNDFDHNNLSAKFRYRQENIPVTIELLPNNTIKVYYPSEAQAVTPGQQVVIYEGQKCLGGAVIEKIYYKGSEKTYL
>NZ_CP022593.1|WP_013456137.1|561964_564607_-|alanine--tRNA-ligase
MKKLTSTEIRQKWLDFFESKNHLVIESKSLIPVNDPSLLWINSGVATLKNYFSGKKVPPAFRLTNSQKAIRTNDIENVGVTSRHHTFFEMLGNFSIGNYFKKEAIAYAKEFLVNVLEMDFEKLYFTYYEEDLEAKNYWLENGVDESHLISGTRDTNFWDLGSGPCGPCTEIFYDRGEKYDSRGIDLLKNDIENDRYIEIWNIVFSQFNNDGEGNYTELKQKNIDTGAGLERLASIMQDVPTNYDSDLFINIIREIEKYSRYKYIIENYFVKDEHQSEINTNFKIIADHIRTVVNAIADGAKVSNVGRGYIIRRLLRRSYYKGMQLGIKDLFLHKLVKVVKDSLPYEYDEKDVIDAIKEEELLFSKTIEKGKILLESFLDNENKVFDGAVAFNLLETYGFPIELTAEILHQKGIRVDMEAFELAKEKHALASKGGKATGMDKVINSLALIDKKMDNFVGYSELSASSKVLKLFDEENEVESFETGGYVLLETTPFYATSGGQRHDKGFIIQGENKIKIIDVFKDKFGNHIHFVEGKMNNYEPVSSFVDPNIRIGLERNHSGTHLLFCALRNVLGSHIEQLGSDNNEERLTFDFPADEKPSDEQIKAIEDLVRSYITKSIDREYITTTVDKAREMGAIMTLEEGEYMDPRAVRVVRFGDITSDLCGGTHLSNTSKLESFKITNVEKKQAGVFRIRAISSIKLVNEYLSEVNKKLNEELATIIKKIKELKNDYVAPVINENEPDIETLNLSINKRIDELREVYKQLLKESSNLEFDYETVKFDKINNYDVYINLDVDASSVKLIAASIRDKFQSGKTVAIIGSKNEKELLLAIATRAIDANKMFKKLSSELNGRGGGAPILAMGKMNYSENIESLIKDYLLNA
>NZ_CP022593.1|WP_013456187.1|561531_561972_-|Holliday-junction-resolvase-RuvX
MRKLSFDLGTKTCGFAISDILEISANALETIRFDENDFNVVITKVKEIIKMYQNSIDAFVLGYPLRSNGSKSERTVMVDNFATLLANEFPGINIYLVDEYGSTIKAQRILKDAKLSNKKTKSKKDTVSAVIILNDFLQYGGQKYEL
>NZ_CP022593.1|WP_013456305.1|560813_561542_-|hypothetical-protein
MSFKEKLVQNGSPTSLGWGLIASAIIASLIGIITSITVFVRAFKIRKQFNKTLEENAKNAIMKIKGSELDAKDEFINKAFSTNINEFDMLHIVKSVYLNYAQNVLIDGLNLENLYLTLKTMTLANIEIDLRAINSKTWNEAVIKFKDKITEKPCFIDSEDKKYNLIISANDNSSNTEIFNKLYPKLTLGGLLMVIQNPIIKSDLKDLKRDLKIKNIRFEASKNKALFLYIVKSESDSLPYLQ
>NZ_CP022593.1|WP_013456453.1|558358_560530_-|hypothetical-protein
MSYIKLEKKFKLLLGTITSAVPLSFVLSCTNNKESVLPKLDDDKMIDKNSDTEAKTPIKQADKHFLAIDQLIKLSPREIHSKTKTYIEKNKKFKNFLKTRNINFISEEYPRHENELDKEYWTYAKYLGEYGNHGDDSYQKTQFFNPSIPIGHYLNHQHLEKFSEEEVKGLEVKTIDLSSLIRNNPFGYLPSNLSQLLSYATYESIEKKFNLRNISNIKSSYDDIKGVIYLLIYTNNNKNKHYYLINKDNNKELKANIDFFTYIKDRSIELNVNAKQWVSTVDQQKNISGIFSFPKFLGTAWVIDRIKNNNKDYYELLLATNMHVFNLRSAFDKTYHYDKFKKYESGYKDKDYQWKEFPPGFYDGIKTDDSGDNRNIKPKPAFKVGRIKENSLDLDFGVFEKNKYKYELDHSDRIDAFEDAYAQYLDAPYYTPRYESNNTYLKAIEKIPETLKNNFSYFNTKNSGADFLTLRLKIKKDKLKNVLPKLASVIGTDEEKDFYVNFSNKEFSPIKTQFYAGYPKHWDPFSKKSQFRGIKSEGGIISTKRRIVDENWFRDVWLRYDEKLNKEYNSENNLWEKYQQPFIKKKDKDDKYQLIKEEHGMPLTTLDQFSTLYTNIPFGDLNLKEGASGSMAIDSSFNVIGILNTRVDNVIGDKKVIKFDKPYGKDGIIDGIVVRPQTNGIVLFKSLSDDYIGKEKQPFIIDGLKNKLINDKLETIKLNPNSK
>NZ_CP022593.1|WP_013456554.1|557461_558184_-|SDR-family-oxidoreductase
MKKLIAITGANSGIGLASAKLFASKNYPMLLIDKNIDVLETIDFKNCLIKKIDVRDFNSLNQAIIEAQKEFGSVDLMLNNAGIMPLDKYYEQSLQDKYDIIDTNIKGVINGMDAVLPSMIKENSGTIINISSTAGRFTYDDHSVYNGSKFAVNAITQQARRELAHTNIRFSLIEPAIVNTNLLSTVKNQKIKDEYLQFQRSIDNGLKPETIAQTILYIYELPQDVTIKEILISHTNESEV
>NZ_CP022593.1|WP_013455952.1|556684_557137_-|SocA-family-protein
MNKKYSYKDVSNWFLSKESMTPKKLQKLTYYAEAWANALLGEGILSDTAFQAWVHGPVSPELWHDYKEYGWNEIEQLKPNDEKFSKNILELLDAVWITYGDKSGYELEAISHSEEPWLKARNGLSEFEISTKVIDPADMKNFYKSIYSGD
>NZ_CP022593.1|WP_013456130.1|556292_556682_-|hypothetical-protein
MNKKLTSELNLNKKTNLFHTNKEIVFKFAIVNKLDNGYDFKSLDLDGLKKFNNFVNDILEKKMTISQVEKTYMRKRFKPLVKRHIEEQDMDVREIHLGKDQQKFRLFGYFNENNYFVLTKIDSKHNFNE
>NZ_CP022593.1|WP_174245827.1|554494_556096_+|IS1634-family-transposase
MSIGVPRPDNKGFVYRLGYGYLHELKQYHDDPLTIIKAIIANFPLSWIKEQARTKLDEILKEKKETKKEVLERFKGYEVVEKLFDYLNIFNDCSPTKSTTLKDVVLQLIYQRIKNPISVFNTYMTAKKEKIDTYSKNSFYRSLDYIAKNKDEILRNLNAQICANTNRKIDVLWFNATTTYFETFSREGYKKPGYSKDGKFKEDQIVIGMATDENGIPLHYKIFPGNVTDSNTFIPFMLEIADIYEVNSVTIIADKGMSVNRNIRFLESKNWKYIISYRMKAGSKQFKEYVLDEKDYVNDGGLIYKTRDIASSYNKKRINEHFRRQIISFSQKRATKDKNDRDILIQNFTKKMNKDNLVSCDDLAGSKKYRFFKPINKGAFYELDIEKIQEDQKYDGYYVYETNRTDLSVKEVINLYSKQWQIESNFKTLKGKLSLRPMYLSTWNHIVGYICLCFISLVFLNYIIYILNSKLGLTGKSKITEHKVINVIKEVKEIEVFVNKQKIETIQVYNDELQESWQTYQILLELLTKEKVT
>NZ_CP022593.1|WP_115300219.1|569153_569930_+|variable-surface-lipoprotein
MKKTNKIIISLSSIISISSMPLIAASCQNKNRTDESIINNITPPQTIDNQKQQEDKSKEEKPNGSGNSSPNTTPQTQDNQNHQEDNIKEKEQSDDPSGSGNSSPNTTPQIQDNQNHQEDNIKEKEQSDDPSGSGNSSSNTNPQIQDNQNHQEDNIKEKEQSDDPRDLLEQLEKIRKDYEKTEKENENLIKNSNYSDVLNNWFGDIYRGRLGHKWNYYLQFKNIVEKRQKPESWFKTVKEFIEEYKTEIEKDLKEQKLI
>NZ_CP022593.1|WP_115266510.1|570313_571342_+|IS30-family-transposase
MKTVSNIVGFKSRSIYNLFDRITIETKRGYAKYQKKCKLCGIDLKGKTIYVISALKFLNLIETRHDSKRLENNSKLLMKYIDIFKFYKQLLYFYLKNRNSFNLDSKAVKQSVASIIFKYIRELEAQGKLQNSYIPSVQNFYRILAKHSAFGLKLDILPYKSNGKYGSRTTVKHETKKKTIGKLITERPESVNLRLNDNDYEMDTVIGLRSDNYCILTLINRKSRMFYCALSRRNAKAIKENLEKLIKDNNLVIDTLTIDNGSENYKLPEIESIKEIFHCHPYSSSEKGSIENAHRLLRRYIPKGKSIDKYVGQDLKPIADFINSHPRIYKGVSGFKCAKQMQ
>NZ_CP022593.1|WP_115266511.1|572208_573219_-|alcohol-dehydrogenase-catalytic-domain-containing-protein
MNKMKAFVVKAPKEYSVELIDIPEPVDNEVLVKLETSGVCHTDLHIANFDWPRQPNYPMVPGHEGIGIVTKVGPNCTKIKVGDRVGVGYMYSACGQCEYCISGKEILCVSRVVTSLVKPGTFAEYTIGHEDYVLPIPKELDIVSGAPILCGGVTSYKALKQAELKVGDYVAIIGIGGLGHFAISYAKAMGLNIVAIDIDDKKLESAKYEGAHYIYNANDLSFVQEVKELTNGGVHAVINTSVSTSSASLAMYILRRAGRQVLVGVPPKDENGKIEFPLSILGTISGEQHVLGSVVGTRQDTKEALILGTKGIVSKIGRIISLDEVKDVFEQLAKGE
>NZ_CP022593.1|WP_013456567.1|573421_574006_-|variable-surface-lipoprotein
MKKSKILILGSIASLGAIPFVAAKCGNENQNSIKEDKTDSQSKSEKSSGTVKKDSTSENSTIDKKENETAPKKQLESENSKSEKSDSVSNMNTEMPKVTESVANETDDGESISDILDDEAKKYFKKEIDAEYENIEKMINKVLKSDSDKKSEVLEYFKKLKTLLNSMFDNAKTFEDIDKIFDYLGKVVIVGKTK
>NZ_CP022593.1|WP_013456478.1|574316_575357_-|zinc-dependent-alcohol-dehydrogenase
MKAFVVTEPKKWSVKEVDVPKPKYKEVLIEMETSGICHTDLHAANYDWLVEPKYPLIPGHEGIGKVVALGEGCTRLKIGDRVALAWLHDACGYCEFCLTGRETLCPNQNMSAYTKDGSYAEYAIGHEDYVGLVPEKLDIVTGAPVVCAGVTTYKSLKQTKAKAGNFVAVIGVGGLGQMAIQYAKAMGLRPIGVDLQDEKCELALKSGAEYAFNSAKDPKFIEKIIEVTGGGVHAVVNTSVHPSAAEQGMDMLRRGGRQVLVGLPAKDKHGKDDFKVSIFWSVLLERELAGSIVGTRQDLAEALEYAAEGKVKSEVTKVVKLEEVADIFEKLQKGEFLGRAVIDFRK
>NZ_CP022593.1|WP_013455921.1|575581_576313_+|DNA-processing-protein-DprA
MNDLLIYFSILFKGNNFEIYKALKNGHKVDKYKVDETINELNEKGIKAITIFDSNYPQGLKELKYSPFVLFYKGNISLLDKNIVCATGDVVNEFVLQNVYQTCGELSKSSVLLTNNFKNIDQNIIEIFNKNKQGIIYLLANGISYNCPDVDFDKDLCITFIPPELHPKLRYFKERNVIAAALSNNLIIFSSKRNSGLINLANCFANLGKNVYCYPGLTYDDGNTYLIKSGASLITHLAEVNYF
>NZ_CP022593.1|WP_115266414.1|576299_577136_-|HAD-IIB-family-hydrolase
MKRKIFSYDLDGTLLMRNNKVHPITKKAFHDVHLKGGINILNTGRGLLKVLPLLDEFDGIDYFICSNGALIYDVKNKNHIVVGQLEPEVFKQMFEYANQNDLIISLDTSNYTATYVNKDANGNFPEWINKQDIMDFSHIKFSDYETMSKVANDSKSIITQVALRNPNEIANETTKYFNNLYKDKYSVYLTNRIYTDVNPLGISKWNGLKEFMRIYNMQDCIIYAFGDSSNDVEMLQNAHFSFAMENATDDAKEAATEVIGHYNSGAIGIKLEEIIKSS
>NZ_CP022593.1|WP_115266415.1|577230_578583_+|YitT-family-protein
MSSPVTNLKIIKRKKLLKKLHSENVNNLKLIELDKEDIDLRKYFGDDLMANLRMTNYTYYTDSANKRKKNVRKRTAILYAKRIFFIFIAALIFNFGVIAFLNRGDTLPSGLSGFPMLAVLIAKDKGYRDWDKYFALMFILINLPLLIGFGFKVKKSFTILTTVFMVSQLITNAIFTSIPQVHNFIHNYINIAPGWHKLVEFRDKAGNIIGTYENSSSWPIIINGFLGSICAGTSIAIAWKNGGSTGGADIIAYYFSTKKQKSVAGMMFTVNIIATSFFLLVFGIAARHKEAVDLGVISSSSSVESVLEQPNSIIITLKDGFTINSIKKYVSHRTIFGLREFSTILYIIFNNIVLGLMYPKYKKVTLSIATKCPDTIINYFKHIKYWHAYTIFKGISGYSQEETYFIETTLLTLETKNLISDIKVIDPKAWISIKPVEQVKGAFNTQYVEQ
>NZ_CP022593.1|WP_115266416.1|578635_581614_-|AAA-family-ATPase
MKLIKVEAHGFKSFAEPITLRFDGGVAGIVGPNGSGKSNINDAIKWVLGERSAKELRGDNMDDVIFAGSKTAKPMDKAVVTLTFDNKDGQSSINHEMITISRVLERGSGINQYYLNGEVCRQKDIKEIAMESGIGKSSLAIISQGTVSDIAEASAEERKGIFEEAAGVSKYKFRKKEALSKLTKTQEGLDQIGLVIAEIERKLNPLRKQAEKTKIFIAKTEELRTVEVGLLVDNIKKFGSRYEELSTELEGVQETKNDLNNRIKDLESKISQNIDFKSNLEASQREISMELDAVKDRLNNLSIAIARENERERLIVEGNIKVDKTEQINAYKTLIEKSMQRIAYFSREYDLISKRVADNNEILDKHDSELNLLNVKLNKKENDIFKIQTHLNLLKQQKEGNTLLYKGTKTILENKAIFGKGLKGTVADLIKVNKEYSRAIEAVLANALQHLVVEKSEVAVKAVEFLKQNNGGRATFIPLASIQPKSVRDDHLLAIQGQPGFIAVASEVVEVEPIYIILSQFLLGNVIVTETIHHANHISKILDNRYMIVTLDGDIIRAGGVIVGGAKSNTETLLTIDLKISELESLLPGIQIAINDDKAKQNEILNERRTCLELDSQLKNQLSNVVSQKSAEQKILDELNLKLKNISERELEIKSDSISIHSSEADLEVLSSRKSALEADFRAKHERINSLSQEINSAQVLKNDFESTLRKLLESFSEKLSEKEKSKLLLDQSRERLASQYKFTLESAEAQGYKLEMSYDQATEIVREIREEISKLGNVNLEALEQLVEEEERYNKFVKSEEELTQAKEVLESAIAQMDKIIITRLTNIIHDVNNEFNDVFATMFGGGSARLFFSDPKNILESGVEIESMPPGKSIKNLKLFSGGEKSLIAISLLFGILKARPLPLCILDEVEAALDESNVVRYAEYLQKLKSKTQFLVITHRHGTMSRVDSLFGATMQNRGVTTFFSLELAEAKKLVDDIQEDYISARQTK
>NZ_CP022593.1|WP_013456004.1|581687_582362_-|ribonuclease-III
MNSIENFLNQFNIKANSLLVYRQAFTHGSSAANAKNKNYQTLEFLGDAILQFYVSAILFNVFKDKNQGQLTLIRAKLVCTDSLNSIADRLKLKDFLLLSSNVVANEVLSSKKVGADIFESLVAAIFIDQGMPKVKEFLDKTLLPLVKQYKEGKIELKDSKTRLQEYMQSFSKKTVFYQTYQSDNNQFKSEAIYEGNVYGSGLGKSKHEAEENAANDALNKLIKS

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Crispr_ID: NZ_CP022593_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022593_3

624073-624215

Orphan

Consensus_repeat	Method
TTTTTCAATACTCAAATTAGGTGCTTTTTAATTTAAGAATTTATA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022593_3

>merge|NZ_CP022593|3|624073-624215|CRISPRCasFinder
TTTTTCAATACTCAAATTAGGTGCTTTTTAATTTAAGAATTTATATTTTTTATTCTTTTGGCTATTCTCTTGTCAGAACCACCAAAAATTGGTATTATTTTTCCAATACTCAAATTAGGTGCTTTTTAATTTAAGAATTTATA

>NZ_CP022593|3|3|624073-624215|CRISPRCasFinder
TTTTTCAATACTCAAATTAGGTGCTTTTTAATTTAAGAATTTATA	TTTTTTATTCTTTTGGCTATTCTCTTGTCAGAACCACCAAAAATTGGTATTAT
TTTTCCAATACTCAAATTAGGTGCTTTTTAATTTAAGAATTTATA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022593.1\|WP_115266435.1\|635916_637755_+\|leucine-rich-repeat-protein	unknown	unknown	gnl\|CDD\|372554
NZ_CP022593.1\|WP_115266422.1\|609079_610012_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226164
NZ_CP022593.1\|WP_078086165.1\|621492_622521_+\|IS30-like-element-ISMbov1-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP022593.1\|WP_115300222.1\|624802_626656_+\|peptidase-S41	unknown	unknown	gnl\|CDD\|143479
NZ_CP022593.1\|WP_075271012.1\|633604_635914_+\|leucine-rich-repeat-protein	unknown	unknown	gnl\|CDD\|372554
NZ_CP022593.1\|WP_013456509.1\|624275_624779_+\|dUTP-diphosphatase	unknown	unknown	gnl\|CDD\|370103
NZ_CP022593.1\|WP_115300220.1\|610014_611370_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|284141
NZ_CP022593.1\|WP_115266430.1\|626687_627584_-\|elongation-factor-Ts	unknown	unknown	gnl\|CDD\|236491
NZ_CP022593.1\|WP_115266431.1\|627633_628587_-\|30S-ribosomal-protein-S2	unknown	unknown	gnl\|CDD\|235396
NZ_CP022593.1\|WP_115266428.1\|619506_620871_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|181958
NZ_CP022593.1\|WP_115266433.1\|631921_633283_+\|variable-surface-lipoprotein	unknown	unknown	unknown
NZ_CP022593.1\|WP_115266427.1\|618610_619396_+\|Nif3-like-dinuclear-metal-center-hexameric-protein	unknown	unknown	gnl\|CDD\|376614
NZ_CP022593.1\|WP_013954706.1\|617076_618606_+\|RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|235640
NZ_CP022593.1\|WP_013456029.1\|629147_630560_+\|IS1634-like-element-ISMbov2-family-transposase	unknown	unknown	gnl\|CDD\|376573
NZ_CP022593.1\|WP_115266432.1\|630580_631402_-\|Dam-family-site-specific-DNA-(adenine-N6)-methyltransferase	unknown	unknown	gnl\|CDD\|273146
NZ_CP022593.1\|WP_115300221.1\|615143_617084_+\|DNA-primase	unknown	unknown	gnl\|CDD\|273595
NZ_CP022593.1\|WP_080551570.1\|622928_623957_+\|IS30-like-element-ISMbov1-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP022593.1\|WP_115266434.1\|633352_633580_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022593.1\|WP_115266424.1\|611820_613614_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236766
NZ_CP022593.1\|WP_115266425.1\|613725_615102_+\|glycine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235240

Protein	Function_ID	Function_description	E-value
NZ_CP022593.1\|WP_115266435.1\|635916_637755_+\|leucine-rich-repeat-protein	gnl\|CDD\|372554	pfam13306, LRR_5, Leucine rich repeats (6 copies). This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.	4.30047e-13
NZ_CP022593.1\|WP_115266422.1\|609079_610012_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226164	COG3638, COG3638, ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism].	1.43062e-56
NZ_CP022593.1\|WP_078086165.1\|621492_622521_+\|IS30-like-element-ISMbov1-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	8.16083e-27
NZ_CP022593.1\|WP_115300222.1\|624802_626656_+\|peptidase-S41	gnl\|CDD\|143479	cd07563, Peptidase_S41_IRBP, Interphotoreceptor retinoid-binding protein; serine protease family S41. Interphotoreceptor retinoid-binding protein (IRBP) is a homolog of the S41 protease, C-terminal processing peptidase (CTPase) family. It is thought to facilitate the compartmentalization of the visual cycle that requires poorly soluble and potentially toxic retinoids to cross the aqueous subretinal space between the photoreceptors and the retinal pigment epithelium (RPE). IRBP is secreted by photoreceptors into the interphotoreceptor matrix (IPM) where it is rapidly turned over by a combination of RPE and photoreceptor endocytosis. It is the most abundant soluble protein component of the IPM, consisting of homologous modules, each repeat structure arising through the duplication (as in teleost IRBP) or quadruplication (in tetrapods) of an ancient gene, arisen in the early evolution of the vertebrate eye. IRBP has been shown to promote the release of all-trans retinol from photoreceptors and facilitates its delivery to the RPE. Conversely, IRBP can promote the release of 11-cis-retinal from the RPE, prevent its isomerization in the subretinal space, and transfer it to photoreceptors. In vivo evidence implicates IRBP as a retinoid transporter in the visual cycle, suggesting a critical role for IRBP in cone function essential for human vision. IRBP is a dominant autoimmune antigen in the eye; IRBP proteolysis analysis has proven a useful biomarker for autoimmune uveitis (AU) disorders, a major cause of blindness. This family also includes a chlamydia-secreted protein, designated chlamydia protease-like activity factor (CPAF), known to degrade host proteins, enabling Chlamydia to evade host defenses and replicate.	2.08697e-09
NZ_CP022593.1\|WP_075271012.1\|633604_635914_+\|leucine-rich-repeat-protein	gnl\|CDD\|372554	pfam13306, LRR_5, Leucine rich repeats (6 copies). This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.	6.48948e-20
NZ_CP022593.1\|WP_013456509.1\|624275_624779_+\|dUTP-diphosphatase	gnl\|CDD\|370103	pfam08761, dUTPase_2, dUTPase. 2-Deoxyuridine 5-triphosphate nucleotidohydrolase (dUTPase) catalyzes the hydrolysis of dUTP to dUMP and pyrophosphate (EC:3.6.1.23). Members of this family have a novel all-alpha fold and are unrelated to the all-beta fold found in dUTPases of the majority of organisms. This family contains both dUTPase homologs of dUTPase including dCTPase of phage T4.	7.0266e-36
NZ_CP022593.1\|WP_115300220.1\|610014_611370_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|284141	pfam06646, Mycoplasma_p37, High affinity transport system protein p37. This family consists of several high affinity transport system protein p37 sequences which are specific to Mycoplasma species. The p37 gene is part of an operon encoding two additional proteins which are highly similar to components of the periplasmic binding-protein-dependent transport systems of Gram-negative bacteria.It has been suggested that p37 is part of a homologous, high-affinity transport system in M. hyorhinis, a Gram-positive bacterium.	9.93823e-43
NZ_CP022593.1\|WP_115266430.1\|626687_627584_-\|elongation-factor-Ts	gnl\|CDD\|236491	PRK09377, tsf, elongation factor Ts; Provisional.	7.10022e-107
NZ_CP022593.1\|WP_115266431.1\|627633_628587_-\|30S-ribosomal-protein-S2	gnl\|CDD\|235396	PRK05299, rpsB, 30S ribosomal protein S2; Provisional.	1.15972e-113
NZ_CP022593.1\|WP_115266428.1\|619506_620871_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|181958	PRK09564, PRK09564, coenzyme A disulfide reductase; Reviewed.	1.17288e-111
NZ_CP022593.1\|WP_115266427.1\|618610_619396_+\|Nif3-like-dinuclear-metal-center-hexameric-protein	gnl\|CDD\|376614	pfam01784, NIF3, NIF3 (NGG1p interacting factor 3). This family contains several NIF3 (NGG1p interacting factor 3) protein homologs. NIF3 interacts with the yeast transcriptional coactivator NGG1p which is part of the ADA complex, the exact function of this interaction is unknown.	4.55049e-48
NZ_CP022593.1\|WP_013954706.1\|617076_618606_+\|RNA-polymerase-sigma-factor	gnl\|CDD\|235640	PRK05901, PRK05901, RNA polymerase sigma factor; Provisional.	0
NZ_CP022593.1\|WP_013456029.1\|629147_630560_+\|IS1634-like-element-ISMbov2-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	2.57572e-07
NZ_CP022593.1\|WP_115266432.1\|630580_631402_-\|Dam-family-site-specific-DNA-(adenine-N6)-methyltransferase	gnl\|CDD\|273146	TIGR00571, DNA_adenine_methylase, DNA adenine methylase (dam). All proteins in this family for which functions are known are DNA-adenine methyltransferases. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). The DNA adenine methylase (dam) of E. coli and related species is instrumental in distinguishing the newly synthesized strand during DNA replication for methylation-directed mismatch repair. This family includes several phage methylases and a number of different restriction enzyme chromosomal site-specific modification systems. [DNA metabolism, DNA replication, recombination, and repair].	4.25469e-81
NZ_CP022593.1\|WP_115300221.1\|615143_617084_+\|DNA-primase	gnl\|CDD\|273595	TIGR01391, DNA_primase, DNA primase, catalytic core. Members of this family are DNA primase, a ubiquitous bacteria protein. Most members of this family contain nearly two hundred additional residues C-terminal to the region represented here, but conservation between species is poor and the C-terminal region was not included in the seed alignment. This protein contains a CHC2 zinc finger (pfam01807) and a Toprim domain (pfam01751). [DNA metabolism, DNA replication, recombination, and repair].	1.66826e-107
NZ_CP022593.1\|WP_080551570.1\|622928_623957_+\|IS30-like-element-ISMbov1-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	9.23257e-27
NZ_CP022593.1\|WP_115266424.1\|611820_613614_+\|hypothetical-protein	gnl\|CDD\|236766	PRK10811, rne, ribonuclease E; Reviewed.	3.87315e-08
NZ_CP022593.1\|WP_115266425.1\|613725_615102_+\|glycine--tRNA-ligase	gnl\|CDD\|235240	PRK04173, PRK04173, glycyl-tRNA synthetase; Provisional.	0

>NZ_CP022593.1|WP_080551570.1|622928_623957_+|IS30-like-element-ISMbov1-family-transposase
MKTVSNIVGFKSRSIYNLFDRITIETKRGYAKYQKKCKLCGMDLKGKTIYVISALKFLNLIETRHDSKRLENNSKLLMKYIEIFKFYKQLLYFYLKNRNSFNLDSKAVKQSVASIIFKYIRELEAQGKLQNSYIPSVQNFYRILAKHSAFGLKLDILPYKSNGKYGSRTTVKHETKKKTIGKLITERPESVNLRLNDNDYEMDTVIGLRSDNYCILTLINRKSRMFYCTLSRRNAKAIKENLEKLIKDNNLVIDTLTIDNGSENYKLPEIESIKEIFHCHPYSSSEKGSIENAHRLLRRYIPKGKSIDKYVGQDLKPIADFINSHPRIYKGVSGFKCAKQMQ
>NZ_CP022593.1|WP_078086165.1|621492_622521_+|IS30-like-element-ISMbov1-family-transposase
MKTVSNIVGFKSRSIYNLFDRITIETKRGYAKYQKKCKLCGMDLKGKTIYVISALKFLNLIETRHDSKRLENNSKLLMKYIDIFKFYKQLLYFYLKNRNSFNLDSKAVKQSVASIIFKYIRELEAQGKLQNSYIPSVQNFYRILAKHSAFGLKLDILPYKSNGKYGSRTTVKHETKKKTIGKLITERPESVNLRLNDNDYEMDTVIGLRSDNYCILTLINRKSRMFYCTLSRRNAKAIKENLEKLIKDNNLVIDTLTIDNGSENYKLPEIESIKEIFHCHPYSSSEKGSIENAHRLLRRYIPKGKSIDKYVGQDLKPIADFINSHPRIYKGVSGFKCAKQMQ
>NZ_CP022593.1|WP_115266428.1|619506_620871_+|FAD-dependent-oxidoreductase
MKIILVGANHAGTSFIRTVKTVNKDVQITAYDRNTNVSFLGCGIAVWVGGEFSQPDGLFYSSPDILRDKYGVDLKTEHEVIKINKDKKEVVVKNLKTGEEFTDSYDKLVFAGGTWPIEPKIPGIEYNNIVLSKLFQHAQHLVELANNDKIKNVVVVGAGYIGIELTEAFWQKGKNVTLIDNNPRVIGNYFDPEFTDIMETNIKKDGVKLALGEMVKEFKSVNGKDVSSVVTDKGEHSADLVIMSVGFRPRTEMVEAEKLPNGTIKVNDFQQILGDENIYVIGDSSAIKHSVTGNHAHVALATNAVKTGVVAALHIAGLNIPFPGVAGTNAINVFGCHYTSTGFTEEAARRNGLTDVASVYFEDFDRPEFMSTSEKVACKIVYDTKTLKLVGAQIGSWGNAIHTETIFMLALAIQKGLTLPEIALTDVYFLPHFNKPFNFVLVPILKALGIDYKY
>NZ_CP022593.1|WP_115266427.1|618610_619396_+|Nif3-like-dinuclear-metal-center-hexameric-protein
MLILKISNYLLKKYILENKEEWDPAGWALHFKLNRRIRGVVVALDLTPAVLEKALSSDSNLIVTHHPFKFYETWEEEFEYAPYKKKIFEALNENRINVLCLHTNYDNYKYGTSYQIAKRLDLSENISHFENTNYPVAIKDVNLPLSNIINAIKQQLNLSQMRTNILNEDINNKIINNIAIFAGSGSISEINKVSSDYDLIITSDVKWSDWLTYSELQTPILEISHLSEQAFVYDIYSQLKETFPDRNISMVEINKEPYSNI
>NZ_CP022593.1|WP_013954706.1|617076_618606_+|RNA-polymerase-sigma-factor
MSKKSELRATVKLIKSHLKNLGKATLTQEEVYEYLDSIKVEVPDDDMDIMLELLLEENILADDFDDGDASFVNSDDIMDEVDAEKSMNKDDQSKGYDDGYSSKMQLKSNETEELEDDSDYSKLIRNYSDNSYDSYEDESEEFMVMDDDYHDSSYDEDDEDDEIVYKTDDKDQVTAKAKRGRKPKTKLNLDTLELEDFSAEEIDLSANLSVKKEDLKNKLTETNDIVKWYMRWIGKYGKLLQPEEEFELATEMDKGGFRGKRARDKLIKRNLRLVINNAKKYKNRGLSFIDLISEGNSGIIKAVQKYNVNKGFKFSTYATWWIRQAITRAVADQSRTVRVPVHMVETINKITKIERELQQENGVDPTDEEIAQRYGNDFTAEKVRHIRKINIDPISLDKQIGKENDSSFSDFVKDESVVNPVEYASHEELVETLNTILKDTLDADEYELICKRYGVGFDNNGEKYKVFSLEELALERNVSKERIRQIENKILRKLKSSPERSRYLKVFME
>NZ_CP022593.1|WP_115300221.1|615143_617084_+|DNA-primase
MSRVPNEIANNIISANDIVDVLRDFIELRKKGQSYVALCPFHNDTNPSMSIDSRRQIFKCFVCNTGGNALTFLKLFKKWSYAESLKYLADKAGIEFIIPDISINEYQNESKLSETDIKVYEVLDKANSFYKSELVKTDNPVIKAFLKNRNLSYNDCNKYDIGYAPIARFRDVFATEIENDLSILINASLVSLNTKEEFFKNRITFGIRDEYNKIVGFSARALDDSKPKYINSSENYYFKKSSILYNLNNIYESANFNQIIITEGFFDVIALNKCNIPEAICLMGTALTKEHVYKLQKFKKIILFLDGDDAGQESTFKTIKTLLQNNYTNIYVVKNNSNLDPDELLNTHGPEAVKSLINDASLYIYFIYDYLRIKFGLYDGYNIIEVNEMQFQKFGSEFYPFWLKLSQNAATVFNEKLKKEYNRDINFIIDKGNSFNNDFSTQDNINLNNYDEFYDVNSIPYYDDVVDSQNYNRVPNFSNPKLYKPVKQEYKQNWIEKMLLILLHYPNLQEFFYKNHSKFPFESIELNSNTLEFDKDLKAIYKKLINHTKISPEEANKIIQKFSEEGKDHFINKFHFSTRDIVQLEKDFAEIYKRARDDDLKRYNSYIVNDLGANSSGLEINNKIVKEILEKQRQNKLKMDDEDQNE
>NZ_CP022593.1|WP_115266425.1|613725_615102_+|glycine--tRNA-ligase
MNNKDKNMSNIINHLKATGFVFQGSEIYGGLSNTWDYGPLGSLLKENIKDLWKKEFIYSEHNNFLIDSKILMNPKVWVTSGHVSNFNDPLIENKVNGKRYRADKIIQEIDPSLVPESMTFEQMHDYLSKNVSEYDGSKCTWSEIRKFNLMFETKQGIIEGEKNLIYLRPETAQGIFVNFKNVLRSTRAKLPIGIGQVGKSFRNEVTPGNFIFRTREFEQMELEVFHDPKDSDFLFNKYLYKAKDFATLLGIKDENVRIRAHEQDELSHYSSATSDIEYLFPFGWGELLGVANRTDFDLKAHMQATGESLEYFDPVTNSKLIPFVIEPSIGLDRLMLALLIDSYDEEAISENDSRIVLRMPNSVAPYKFAILPLVKKLNDKAEEIYKELLKLNIAITYDDAGSIGKRYRRQDSIGTPYCITVDYDSLNDECITIRNRDSMLQERISISELYNLAKNYFK
>NZ_CP022593.1|WP_115266424.1|611820_613614_+|hypothetical-protein
MKRLNCTYEIKQDNNFPWLLKHPKVKKGLAKFKTREEALNWYMLLDYETAVWFQDNQKIFAGQLTIDYEDGEWYYYIKTKDFDGDATYDGVCHELGINPYNYKRDRDAEIKKGKKLVEGRDYILISDPATYFPLNLEISKRKRKDVVDIEHMKVQYETKILSLQEQINSNDEHISEELKQSREELAKKELELKEISNKINLLKQNTLSRQEVKYVQFIELKGSDIFGATALYNDKIKKAIESLDNKKISWDDFNRIKKNFSDFESSIIYKKSRMSDKGLRLISILYDEFKTVSIELLSKLEPIDDLDDSFANRAFYKGSEGKLISVSWELSFVLVEFMHVGFVPEDEYAYSIPYLVERSKYLVTLIDAGDNNKIVTFQPGLEQTSEIELDEAKEDVVETKTVQLSEKVEIKEEIKKPTLIYYELAKPEPIAEPEPVAVAEEKTEVVPEVSEPTEVKETTIIIYNLVKEEPAVEKVDAPVTVAEEDEVKEASVIPVVVEEKPVEVEEVETIKPVENQPYFYEDRVASNVAIEDYTLPAEEQMPAVTKDEAKEKGTVAKKNILFYVAVTLLVLLIIAIVTISILGIVHLTTDIKFFKSL
>NZ_CP022593.1|WP_115300220.1|610014_611370_-|ABC-transporter-substrate-binding-protein
MKKMNLIAMAGGLSFLTASPLLAISCGNTSPYQNTVVDEKKEDIAKSWDKEISITNGWINNGFLNTKLETDFLDLLGKRFNDLKNKDSKTKDLPDVKFVIKTDEEGKYFTKLTSNNKANDLYISNYTQYIDELWKDGKFNEKFAPKLVSQASTLKFTWSSDDNDLYSDGSSKDKLRLHADKNNVKWTKELGKEYPEWHEITGEGKKLHFDGSKYTNFYEKKDVTYIYHGAVYISGNKATRDAIVKAWNEKKWDDFYKHGISFEKTSSAGKYKYQVALFARHFGKTVQEINKFLTENDEYVVRGKSAKDSLGKETEDKTGKKKLTPHISFDDEGAYNWTLSKKTSTKYRPSKFNEGKSYDDAENDVVRVLTLTNPAPYDMVLARVGLSNTQVNLISKALQSLSLTENTYGIYSGYNKFQPLNKELLEILTKFQVRAESKQDFEGLKVVSPKA
>NZ_CP022593.1|WP_115266422.1|609079_610012_-|ATP-binding-cassette-domain-containing-protein
MSKVIELKGIYAKYNKKSDFILENLNLDVNEGEFIAIIGPSGVGKSTLFKVLVNAINVSKGEIKIFGQNIYKKSVKDNKLTDNKLTETHKKLDNKSSYDSNLAPDNHFSESVDDENKNTNSKTKKGIFNSEKLFLKRQKKKIMTRIGFLTQKPNLINTENVYNNIIRSISQYENWFYKLFSIITKKQKINIFSKLDELGILDKAFYKVSDLSGGQQQRVEIAKLLVKNVDLILADEPTSNLDRQNSLEVLAILREISKQGKTIIVNIHDLGLVKENFDRVIAIKNKTIVFDKLTKDVEQCELNQIIETKT
>NZ_CP022593.1|WP_013456509.1|624275_624779_+|dUTP-diphosphatase
MNLKKIFEMQKDLDKAIISRNDIDASNSKISQAEFDEMKLLATLVETAEFANEVQSFKYWKANKSINREKALEEFADMLHFVGSFAYKYNVDPDIEPLILSDNVNKQICLLFSTISSAINNLNKYVISQMLAIALGVAKLLNYSEDEIIHWYYIKNKKNYERIKEKY
>NZ_CP022593.1|WP_115300222.1|624802_626656_+|peptidase-S41
MKKIIKKLSISFLPLLTAPLIAAKCFGNSITTTNQNYTVERHTFVNAVKDYEHIGKEGIDTYYFNNDRIPYVSVKQALSALEGVVNTKLIKIGNAFNVLHNKNYQIYHANGASLKFNWENNVIEISDPRVFGILSGKKSIGIMHNLTPLSFKSTYINDKPQSIKFDLSKYNWKIHAVNKEPIIPLFVFNLLFLSQNYYNLRFNGSEYYGVDINTIIRTSPNALSELTNKFKINPETSVQRQDAFQSLRFVFDNFYGLAEEKKIDKVGFESWLDPSIKKDILNRDPLIYNKGYFKALHGQVNELHASVRQFNYYTPLEYTDTNYIRSLVKHSLDEYKNKVDPKFNSKWLNAGQLRSKLNALRESAQYYDDSESRRLLKVSQTINGLRLVEGNVPVVRFLPDNKSAVITLDSFSAASPEENYIFDSLELMKYALDVIERRSIVTGNKINNIILDISQNGGGNVAALYKLIGLIKGKQDRKAYSYSFNTLTKTLEESVYRAEIPNKYLDKNYKWFLLTSNLSFSAANALVAYTAADKSSPSSRNVQIIGQRTGGGACAIIPIVLSDGTMIVVSSNTKIMTKSNDKHYVSVENGFEVPDKYKLNYEDFYNDHALAELVSKK
>NZ_CP022593.1|WP_115266430.1|626687_627584_-|elongation-factor-Ts
MDKMALIKELRERTAAGMSDCKKALEASNWDVEEAISFLKKNGKIKAASKANRVSADGLLVEAGDSNRAVLVELNCETDFVAHGDEFVALANTVAKTIVANYELVKENGAEAALALKAEGSDESLADLISSYSAKCGEKIELRRFALIDAGTGQSVSTFVHINGKIGAILLTNGVNAEAARNVAMHLSAMNPEYIFADDIPSYVLERFASEFKEPAGFENKPEKIQETIRKGFVDKKISEVTLLSQRLIMDESKTVEQYLKDNKLSLIKAIRFGLGEGIEKKETDFAAEVAEQMNKSM
>NZ_CP022593.1|WP_115266431.1|627633_628587_-|30S-ribosomal-protein-S2
MENENLKVEQATTAESNMAEKADDSKASKEVKPTIVSREKLLEAGTYFGHKKSMWNPKMKEFLYPQSKRGMHMINTNVTLQRLEFAYNILNKFVAKNPRTTFIFVGTKKQAKDTIKENALRTGSFYVSERWLGGILTNASTIFKRVKVMEELEAQAAKKFQGYTKKEGLIKQKELDKLHKNLDGIRKMQSLPSFMIVADPNVDAIAVKEARSKGVKVIGILDSNSNPDAVDFGIPANDDSAKSITLIMTILADAIATARGGKAKFAYQGDDKVILPEFKTDRVQNPRFVNQRRSFEQTGGQTVRNVEKTTTSAEVTE
>NZ_CP022593.1|WP_013456029.1|629147_630560_+|IS1634-like-element-ISMbov2-family-transposase
MAIPKDILKIPRPSSTRVKATSKEGIYNVIQRTSIRKNEKIIPVEKGVIGKIINGVFQSIEKQTYEVDIKSYGLFALNEKLNNHIFRELLNFYDFEDARKLYVIASLRTMFSDIKNEHLKHEYDTNFISEIYPKCALSPNTISSFLEKIGKSSSKMEDFMNKRLEEFSNHSIVIDGMLKNNTSETNIFSEMSRKSRTKGAQNLNLIYAYDINAQEPVASSVYPGNMLDYTAFRDFLRTYKIKNGFLILDRGFDDKECKNLMREKNIKYLMPIKINHTFKKFNLKSGFNFTFTYDDDTIRAKKIIINNKYYLCYKSTLTEMVEKKNFISRAHKKGAYDEIKLLERENLFGLIIFECNYDLDLKDIYVAYKKRWEIELLFKQFKNVLEQNEANVQGNYRLLATEFINFLSSIMLCRIKNHLLNSGVLDNRTISETFRYLSKIIKKRKSRKREEWDDVETLKYIKELKSILKI
>NZ_CP022593.1|WP_115266432.1|630580_631402_-|Dam-family-site-specific-DNA-(adenine-N6)-methyltransferase
MLSSTTPSPFVKWAGGKRQLLEEILNKIPSEFNNYYEPFVGAGALLFSLKYNQVSYVNDINKSLIHTYKIAKDSPNELIDKLNELDNKFTSKSDYYECRNLFNEMIQKGNYDVLHAALFIYLNKRCFNGLYRVNSKGLFNVPFNNKENIRSFDKDNILKASEWLQNKVITSTDFEMAVKTASKGDFVFFDSPYAPLNNSTFTSYAKDGFTLDDHKRLAKVFKELDKRGCYLMLTNHNTELIRDLYKDYYITVIKVKRLINSNANKRVGEEVII
>NZ_CP022593.1|WP_115266433.1|631921_633283_+|variable-surface-lipoprotein
MKKNKLLLSLGSLSIFSAIPFIAAKCDITEAKDNSSKEPGTTNPGTTEKESAKVDLDKLSDKVKEELNKLAKEKVTKEEVVAVLKTEKGLEKLTAEDLTKVEFKDNKLTIEAHKESKLVSGTYVFDAQVQPPKTDSVIDLSTLQLNADVKKALKIEAKINPDKKKIIEAFKKDNNFAKLTEDDFEATFKDTILTIKSKPESTVIKGELQVHTKTELDNVTLTENIKKELQAELQEESFNAEEIVKVLKKLPELKDLDTKKAEFKKENNKLLVTAKKESTKFTGSLSFIFKVALDKAVVKDIKNELSSEVKKDPSMPHIVNILKKIPGLVTISANDVKVEFKDNKLVITAMDKSEIVMGSVSVEKSKDSAKINLSSYDFTEKDKKSILNALSESDDPEGDQIKSSVWFSLTTIFKGRGIEESDFEVTFDKEKKTLTIKASKETKKLEGEKTFNE
>NZ_CP022593.1|WP_115266434.1|633352_633580_+|hypothetical-protein
MLLEEFEDGINTMLSAQKLLKGIEELKNITLADIDDKIETEKESSEKDVFKKVTIKAGSTSKLISGTLVIEKKDK
>NZ_CP022593.1|WP_075271012.1|633604_635914_+|leucine-rich-repeat-protein
MKLKKIFNKYIAIVPALVTITLIAAKCEYDPGVKVFYDLNQLRLEAVEKESLELIDNYEKNITKFWSDRQALNELKKLAAKVREIENKAEQELKEYSEPAKAKVEHEDSDEKDSSVLTAKKALAKFDRSATEIKIPSEFTKIGKNAFNNFYNLGKIEFHDNVTEIRQGAFDNTDLDSVTLPKNLKVLGGFANTYIKTLEIPQSVTKILQGSFDNTNIGTIKLPEKLTELGGFKATGISELKLPESLTKIYENSFDETPITKLKLNKNLKILGGFNTLRNLEEFEFNDQLEEILDESFLNFNLTSLKLPNSLKILGGFQQSNITDLSLNEGLIEIKPNSFAESKGIKRLSLPQSLKKLGGFQGTNILALRLPKGLESISKNAFDKTIITDLDLPEGLVSFGGFAESQISEIKFPKSLLHIEPNTLDFKKARNKEYKLELPEKLISFGGFKNWNISEIKFPETLRDIWAETLDYSKISELNLPSNLNSFGGFAGTKIKSIQFPESLKIIHQNTLDETKISEIRLPNKLEVLGGFANTPITKLSTPKSLKTTLKETFRNSKLNRIRFNKGLIELAGFENLVDIDAITLPETLLEIKDGAFANNRLKEIKLPSHLKVLSGFSGKSSEIKEVVLPESLEIIGNSTFNFNDHITSVKLPSKLIEVSGFSSTNIRELDIPESVIKLGGFNQTLIRNLKLPDNLESFEGFHESKIKKLVFPKFLRFADISKSHWKSLETIDVYSKYLVKSKWWNNMKEDDYNQLIKLVDKTNSRRDK
>NZ_CP022593.1|WP_115266435.1|635916_637755_+|leucine-rich-repeat-protein
MKKFSFVLLPILTFPAIAAACDNKDKATKNPDNQDQSASEIQKLKDELQYEITKATSKRNHYLGDYTDYAFNQSAKVIQEAVYVHHNAKTVEEVKKAIEKLKAGIKEIDAYFALSKEEKQKLARKDFNKALVAAKEAKAKLTKPSAIEVLDDSIAKAESNKEGDPHYFTNLLKWTYKSKKDIEEAQKLEEKSDKELLKLYLSKESNILNTFNREYNASGSFDEQAEKLKEIFKKANENKKEDYRDQEVKLRKEISEILEKISKEAITPSKANELAKLVKNGELIIGDDYKYILSDAFADNKKIKKVTLGKKIEKIERGAFDNSGVETITFNENLKSLEGFNNTKVKELTLPKKLEKFAAFNSTKITKLLLPKTLKSFALSSTFLEELEFESDFKFDTVSPDSYYDSIAINQQLLPSLNKIYVSDGSAKKNLLEKLNKNITESKKIKLGEDYIKFLAYIVNVKIVKKFASITEDKKKKIIEALLESSIKKEETKKTKSGIEKIVADLKSENLKDTLEKVLDSYKYEKISAKNKFEVFDAAIEMLKDILRAYGFYLKTETIKNDPDLKQYHHETGVTPGEIINYFDSEKEKYENGKNGSDSNQWENIVQVKPKK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP022593_3	3.1\|624118\|53\|NZ_CP022593\|CRISPRCasFinder	624118-624170	53	NZ_CP022593.1	112941-112993	0	1.0
NZ_CP022593_3	3.1\|624118\|53\|NZ_CP022593\|CRISPRCasFinder	624118-624170	53	NZ_CP022593.1	447483-447535	2	0.962
NZ_CP022593_3	3.1\|624118\|53\|NZ_CP022593\|CRISPRCasFinder	624118-624170	53	NZ_CP022593.1	751179-751231	2	0.962
NZ_CP022593_3	3.1\|624118\|53\|NZ_CP022593\|CRISPRCasFinder	624118-624170	53	NZ_CP022593.1	895501-895553	2	0.962
NZ_CP022593_3	3.1\|624118\|53\|NZ_CP022593\|CRISPRCasFinder	624118-624170	53	NZ_CP022593.1	474855-474907	2	0.962

1. spacer 3.1|624118|53|NZ_CP022593|CRISPRCasFinder matches to position: 112941-112993, mismatch: 0, identity: 1.0

ttttttattcttttggctattctcttgtcagaaccaccaaaaattggtattat	CRISPR spacer
ttttttattcttttggctattctcttgtcagaaccaccaaaaattggtattat	Protospacer
*****************************************************

2. spacer 3.1|624118|53|NZ_CP022593|CRISPRCasFinder matches to position: 447483-447535, mismatch: 2, identity: 0.962

ttttttattcttttggctattctcttgtcagaaccaccaaaaattggtattat	CRISPR spacer
ttttttattcttttagccattctcttgtcagaaccaccaaaaattggtattat	Protospacer
**************.**.***********************************

3. spacer 3.1|624118|53|NZ_CP022593|CRISPRCasFinder matches to position: 751179-751231, mismatch: 2, identity: 0.962

ttttttattcttttggctattctcttgtcagaaccaccaaaaattggtattat	CRISPR spacer
ttttttattcttttggccattttcttgtcagaaccaccaaaaattggtattat	Protospacer
*****************.***.*******************************

4. spacer 3.1|624118|53|NZ_CP022593|CRISPRCasFinder matches to position: 895501-895553, mismatch: 2, identity: 0.962

ttttttattcttttggctattctcttgtcagaaccaccaaaaattggtattat	CRISPR spacer
ttttttattcttttagccattctcttgtcagaaccaccaaaaattggtattat	Protospacer
**************.**.***********************************

5. spacer 3.1|624118|53|NZ_CP022593|CRISPRCasFinder matches to position: 474855-474907, mismatch: 2, identity: 0.962

ttttttattcttttggctattctcttgtcagaaccaccaaaaattggtattat	CRISPR spacer
ttctttattcttttggccattctcttgtcagaaccaccaaaaattggtattat	Protospacer
**.**************.***********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

73600 : 84961

Bodo_saltans_virus(28.57%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013954527.1\|73600_74581_+	lipoate--protein ligase	A0A2H4UVX5	Bodo_saltans_virus	3.9e-15	27.1
WP_115266292.1\|74584_75406_+	alpha/beta fold hydrolase	G9E3U1	Emiliania_huxleyi_virus	3.9e-08	32.5
WP_115266293.1\|75489_76254_+	hypothetical protein	NA	NA	NA	NA
WP_013456612.1\|76246_77227_+	aspartate--ammonia ligase	A0A1C9C5F0	Heterosigma_akashiwo_virus	1.8e-52	40.3
WP_115266294.1\|77351_81728_+	PolC-type DNA polymerase III	A0A0K2SUJ2	Clostridium_phage	8.1e-12	31.8
WP_115266295.1\|82133_83357_+	AAA family ATPase	A0A127AWE7	Bacillus_phage	1.5e-61	35.1
WP_115266296.1\|83346_84312_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2H4UW22	Bodo_saltans_virus	3.6e-29	40.9
WP_013456493.1\|84301_84961_+	uracil-DNA glycosylase	A0A068EP41	Falconid_herpesvirus	1.6e-28	36.4

DBSCAN-SWA_2

157789 : 249215

Enterobacteria_phage(14.29%)

tRNA,transposase,integrase

attL 236108:236135|attR 245998:246025

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_075271214.1\|157789_158926_+\|tRNA	tRNA 4-thiouridine(8) synthase ThiI	NA	NA	NA	NA
WP_013455960.1\|158969_159248_-	hypothetical protein	NA	NA	NA	NA
WP_143823108.1\|159289_160771_-	BspA family leucine-rich repeat surface protein	NA	NA	NA	NA
WP_174245895.1\|161002_162469_-	DUF285 domain-containing protein	NA	NA	NA	NA
WP_075271216.1\|163099_165535_+	hypothetical protein	NA	NA	NA	NA
WP_075271217.1\|165686_168176_+\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	5.8e-140	39.9
WP_075271218.1\|168178_169039_+	bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	1.3e-33	37.6
WP_013954592.1\|169138_170095_+	phosphate acetyltransferase	NA	NA	NA	NA
WP_013954593.1\|170098_171292_+	acetate/propionate family kinase	NA	NA	NA	NA
WP_101456651.1\|171307_171730_+	pantetheine-phosphate adenylyltransferase	NA	NA	NA	NA
WP_101456652.1\|171729_172311_+	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_101456653.1\|172338_173835_+	hypothetical protein	NA	NA	NA	NA
WP_101456654.1\|173971_175408_+	pyruvate kinase	NA	NA	NA	NA
WP_101456655.1\|175476_176457_-	hypothetical protein	NA	NA	NA	NA
WP_101456656.1\|176707_178501_+	molecular chaperone DnaK	A0A0G2YAL1	Acanthamoeba_polyphaga_mimivirus	2.5e-129	45.8
WP_174245822.1\|178694_180296_-\|transposase	IS1634-like element ISMbov3 family transposase	NA	NA	NA	NA
WP_115266318.1\|180602_181886_-\|tRNA	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	NA	NA	NA	NA
WP_013954601.1\|182044_182428_+	membrane protein	NA	NA	NA	NA
WP_115266319.1\|182565_183555_-	lactate dehydrogenase	M1HKI4	Acanthocystis_turfacea_Chlorella_virus	7.9e-40	32.9
WP_115266320.1\|183964_184765_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_013954605.1\|184880_185042_+	hypothetical protein	NA	NA	NA	NA
WP_013954606.1\|185218_185671_+	hypothetical protein	NA	NA	NA	NA
WP_115266321.1\|185838_188262_-	DEAD/DEAH box helicase family protein	NA	NA	NA	NA
WP_013455963.1\|191798_193304_-	trigger factor	NA	NA	NA	NA
WP_013456067.1\|194860_195316_+	hypothetical protein	NA	NA	NA	NA
WP_174245811.1\|195880_196039_+	hypothetical protein	NA	NA	NA	NA
WP_013954613.1\|196167_197577_-	hypothetical protein	NA	NA	NA	NA
WP_013456364.1\|197546_199853_-	S8 family serine peptidase	NA	NA	NA	NA
WP_013954995.1\|200073_201318_-\|transposase	IS3 family transposase	Q6H9S3	Enterobacteria_phage	4.1e-09	27.0
WP_115300205.1\|201644_202415_+	hypothetical protein	NA	NA	NA	NA
WP_115300206.1\|202555_204391_+	BMP family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_078086164.1\|205771_207373_-\|transposase	IS1634-like element ISMbov3 family transposase	NA	NA	NA	NA
WP_013456284.1\|207619_208849_-	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_013456433.1\|208959_210321_+	peptidase M17	Q6GYZ8	Mycoplasma_phage	3.1e-103	56.4
WP_013455911.1\|210424_211321_-	hypothetical protein	NA	NA	NA	NA
WP_013456619.1\|211320_212625_-	hypothetical protein	NA	NA	NA	NA
WP_075271001.1\|213004_214189_-	phosphoglycerate kinase	NA	NA	NA	NA
WP_075271002.1\|214405_215407_+	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	1.7e-10	23.1
WP_013456213.1\|215583_215823_+	hypothetical protein	A0A172JI00	Bacillus_phage	4.6e-10	40.9
WP_013456099.1\|215894_216719_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_013456411.1\|216737_218096_+	signal recognition particle protein	D6PHS7	uncultured_phage	8.7e-05	29.0
WP_013456353.1\|218112_219078_+	YwaF family protein	NA	NA	NA	NA
WP_115266325.1\|219294_220443_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	8.4e-102	52.2
WP_013456580.1\|220705_221107_-	hypothetical protein	NA	NA	NA	NA
WP_115266326.1\|221097_222489_-\|tRNA	glutamate--tRNA ligase	A0A222YZ70	Escherichia_phage	1.1e-07	24.9
WP_115266327.1\|222776_224819_+	peptidase S41	NA	NA	NA	NA
WP_115266328.1\|224845_226804_+	peptidase S41	NA	NA	NA	NA
WP_013456193.1\|226785_227340_+	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_174245901.1\|228305_229907_-\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_115266330.1\|231328_231808_+	hypothetical protein	NA	NA	NA	NA
WP_115300208.1\|231880_232519_-	hypothetical protein	NA	NA	NA	NA
WP_013455926.1\|232893_235572_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	9.1e-91	39.6
WP_115300209.1\|235576_236155_+	restriction endonuclease subunit S	NA	NA	NA	NA
236108:236135	attL	NA	NA	NA	NA
WP_115266333.1\|236278_237580_+	AAA family ATPase	NA	NA	NA	NA
WP_115300210.1\|240126_241263_+	restriction endonuclease subunit S	NA	NA	NA	NA
WP_115300211.1\|241271_244469_+	HsdR family type I site-specific deoxyribonuclease	NA	NA	NA	NA
WP_038582887.1\|244514_245435_-\|integrase	site-specific integrase	A8ATD6	Listeria_phage	1.0e-78	48.0
WP_115300234.1\|245449_245851_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_013954691.1\|247970_249215_+\|transposase	IS3 family transposase	Q6H9S3	Enterobacteria_phage	5.3e-09	27.0
245998:246025	attR	NA	NA	NA	NA

DBSCAN-SWA_3

373698 : 450501

Faecalibacterium_phage(26.67%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080551570.1\|373698_374727_+\|transposase	IS30-like element ISMbov1 family transposase	A0A2K9V2S9	Faecalibacterium_phage	6.5e-21	33.3
WP_013455983.1\|375320_376283_-	DNA polymerase III subunit delta	NA	NA	NA	NA
WP_013456269.1\|376466_377525_+	site-specific DNA-methyltransferase	S4VS49	Pandoravirus	2.8e-19	29.4
WP_078086167.1\|377751_379353_+\|transposase	IS1634-like element ISMbov3 family transposase	NA	NA	NA	NA
WP_013456160.1\|379486_380194_-	MjaI family restriction endonuclease	E3SIW0	Synechococcus_phage	2.6e-21	35.1
WP_080551570.1\|381325_382354_+\|transposase	IS30-like element ISMbov1 family transposase	A0A2K9V2S9	Faecalibacterium_phage	6.5e-21	33.3
WP_115300213.1\|382489_383218_+	BspA family leucine-rich repeat surface protein	NA	NA	NA	NA
WP_013456339.1\|383432_384254_-	DNA-binding protein WhiA	NA	NA	NA	NA
WP_013456083.1\|384342_385530_-	phosphopentomutase	NA	NA	NA	NA
WP_013456498.1\|385663_386911_-	hypothetical protein	NA	NA	NA	NA
WP_013455970.1\|387046_389011_+	NAD-dependent DNA ligase LigA	Q332J4	Clostridium_botulinum_C_phage	3.9e-83	31.7
WP_075271152.1\|389196_391407_+	putative immunoglobulin-blocking virulence protein	NA	NA	NA	NA
WP_075271115.1\|391439_394049_+	hypothetical protein	NA	NA	NA	NA
WP_075271114.1\|394123_396352_+	putative immunoglobulin-blocking virulence protein	NA	NA	NA	NA
WP_075271112.1\|396547_398797_+	putative immunoglobulin-blocking virulence protein	NA	NA	NA	NA
WP_075271146.1\|398826_401403_+	hypothetical protein	NA	NA	NA	NA
WP_115300214.1\|401456_402968_+	hypothetical protein	NA	NA	NA	NA
WP_075271108.1\|402954_403452_+	DUF2714 domain-containing protein	NA	NA	NA	NA
WP_075271107.1\|403451_404372_+	hypothetical protein	NA	NA	NA	NA
WP_075271106.1\|404371_404836_+	hypothetical protein	NA	NA	NA	NA
WP_075271104.1\|404825_407069_+	hypothetical protein	NA	NA	NA	NA
WP_041309119.1\|407072_408647_+	ATP F0F1 synthase subunit alpha	NA	NA	NA	NA
WP_013456309.1\|408646_410026_+	F0F1 ATP synthase subunit beta	NA	NA	NA	NA
WP_013456496.1\|410048_411119_+	hypothetical protein	NA	NA	NA	NA
WP_115266350.1\|411137_413528_-	hypothetical protein	NA	NA	NA	NA
WP_013456170.1\|413683_414574_-	DegV family protein	NA	NA	NA	NA
WP_013456573.1\|414615_416262_-	hypothetical protein	NA	NA	NA	NA
WP_115266351.1\|416276_418481_-	UvrD-helicase domain-containing protein	A7KV33	Bacillus_phage	6.2e-93	35.1
WP_013455988.1\|418505_419174_-	hypothetical protein	NA	NA	NA	NA
WP_013456111.1\|419175_420180_-	glycosyltransferase	NA	NA	NA	NA
WP_115266352.1\|420189_421551_-\|tRNA	asparagine--tRNA ligase	M1PB22	Moumouvirus	1.6e-67	34.0
WP_013456505.1\|421914_422676_+	membrane protein	NA	NA	NA	NA
WP_013456102.1\|422825_423146_+	hypothetical protein	NA	NA	NA	NA
WP_013954838.1\|423148_423727_+	DNA integrity scanning protein DisA nucleotide-binding domain protein	NA	NA	NA	NA
WP_013456233.1\|423730_425191_+	magnesium transporter	NA	NA	NA	NA
WP_013456142.1\|425279_425582_-	hypothetical protein	NA	NA	NA	NA
WP_013456043.1\|425581_426145_-	elongation factor P	NA	NA	NA	NA
WP_013456488.1\|426477_427416_+	hypothetical protein	NA	NA	NA	NA
WP_013456600.1\|427582_429400_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	7.5e-36	24.9
WP_115266353.1\|429392_431189_-	ATP-binding cassette domain-containing protein	Q6GYZ6	Mycoplasma_phage	2.4e-34	44.7
WP_080551570.1\|431444_432473_-\|transposase	IS30-like element ISMbov1 family transposase	A0A2K9V2S9	Faecalibacterium_phage	6.5e-21	33.3
WP_013456055.1\|432860_434804_-	hypothetical protein	NA	NA	NA	NA
WP_013456447.1\|434840_435770_-	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_115266354.1\|435859_436135_-	Smr/MutS family protein	NA	NA	NA	NA
WP_013456282.1\|436118_436958_-	bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase	G3MA33	Bacillus_virus	3.8e-27	34.1
WP_115266356.1\|436959_438252_-	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_115266357.1\|438253_439504_-	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_013456131.1\|439517_439850_-	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_115266358.1\|439987_441352_-	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	7.6e-126	54.4
WP_115266359.1\|441748_442939_+	elongation factor Tu	A0A076FFS6	Aureococcus_anophage	7.5e-29	25.9
WP_115266360.1\|443130_443535_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_115266361.1\|443534_444092_+	hypothetical protein	NA	NA	NA	NA
WP_115266362.1\|444093_445023_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	5.5e-51	36.6
WP_115266363.1\|445047_446919_+	hypothetical protein	NA	NA	NA	NA
WP_115266364.1\|446981_447353_-	PTS transporter subunit EIIB	NA	NA	NA	NA
WP_115266507.1\|447597_448626_-\|transposase	IS30-like element ISMbov1 family transposase	A0A2K9V2S9	Faecalibacterium_phage	1.9e-20	32.9
WP_115266365.1\|449085_450501_+\|transposase	IS1634-like element ISMbov2 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

592499 : 652782

Faecalibacterium_phage(20.0%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013456122.1\|592499_594203_-\|tRNA	aspartate--tRNA ligase	A0A2K9KZX5	Tupanvirus	2.0e-14	23.1
WP_013456205.1\|594271_595588_-\|tRNA	histidine--tRNA ligase	A0A2K9L0H9	Tupanvirus	2.7e-11	25.1
WP_115266417.1\|595826_597497_+	amino acid permease	NA	NA	NA	NA
WP_013456295.1\|597547_598003_+	Sua5/YciO/YrdC/YwlC family protein	NA	NA	NA	NA
WP_115266418.1\|598079_599408_+	hypothetical protein	NA	NA	NA	NA
WP_013456088.1\|599542_599869_-	30S ribosomal protein S18	NA	NA	NA	NA
WP_013456362.1\|599888_600287_-	single-stranded DNA-binding protein	A0A0H3U4B5	Staphylococcus_phage	9.3e-08	30.3
WP_013456432.1\|600328_600766_-	30S ribosomal protein S6	NA	NA	NA	NA
WP_174245815.1\|601132_602986_+	type I DNA topoisomerase	A0A2P1ELA0	Moumouvirus	3.7e-75	32.2
WP_115266512.1\|603130_604177_-	alcohol dehydrogenase catalytic domain-containing protein	A0A0K0KVL7	Prochlorococcus_phage	1.3e-13	26.6
WP_174245828.1\|604420_606934_+	preprotein translocase subunit SecA	NA	NA	NA	NA
WP_013456114.1\|607014_607260_+	DUF2188 domain-containing protein	NA	NA	NA	NA
WP_115266421.1\|607364_609116_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_115266422.1\|609079_610012_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	4.4e-08	30.0
WP_115300220.1\|610014_611370_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_115266424.1\|611820_613614_+	hypothetical protein	NA	NA	NA	NA
WP_115266425.1\|613725_615102_+\|tRNA	glycine--tRNA ligase	A0A2I2L3K8	Orpheovirus	1.3e-53	32.2
WP_115300221.1\|615143_617084_+	DNA primase	A0A1S5RFD7	Helicobacter_phage	9.7e-42	35.3
WP_013954706.1\|617076_618606_+	RNA polymerase sigma factor	G8CLC7	Synechococcus_phage	2.0e-29	33.7
WP_115266427.1\|618610_619396_+	Nif3-like dinuclear metal center hexameric protein	NA	NA	NA	NA
WP_115266428.1\|619506_620871_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_078086165.1\|621492_622521_+\|transposase	IS30-like element ISMbov1 family transposase	A0A2K9V2S9	Faecalibacterium_phage	6.5e-21	33.3
WP_080551570.1\|622928_623957_+\|transposase	IS30-like element ISMbov1 family transposase	A0A2K9V2S9	Faecalibacterium_phage	6.5e-21	33.3
WP_013456509.1\|624275_624779_+	dUTP diphosphatase	S6AVW3	Thermus_phage	7.4e-10	32.8
WP_115300222.1\|624802_626656_+	peptidase S41	NA	NA	NA	NA
WP_115266430.1\|626687_627584_-	elongation factor Ts	NA	NA	NA	NA
WP_115266431.1\|627633_628587_-	30S ribosomal protein S2	NA	NA	NA	NA
WP_013456029.1\|629147_630560_+\|transposase	IS1634-like element ISMbov2 family transposase	NA	NA	NA	NA
WP_115266432.1\|630580_631402_-	Dam family site-specific DNA-(adenine-N6)-methyltransferase	A0A1S5PRR3	Streptococcus_phage	2.3e-53	45.4
WP_115266433.1\|631921_633283_+	variable surface lipoprotein	NA	NA	NA	NA
WP_115266434.1\|633352_633580_+	hypothetical protein	NA	NA	NA	NA
WP_075271012.1\|633604_635914_+	leucine-rich repeat protein	NA	NA	NA	NA
WP_115266435.1\|635916_637755_+	leucine-rich repeat protein	NA	NA	NA	NA
WP_115266513.1\|637718_639806_+	peptidase S41	NA	NA	NA	NA
WP_013455951.1\|639917_641357_+	DNA recombination protein RmuC	NA	NA	NA	NA
WP_013456519.1\|641421_643032_-	dicarboxylate/amino acid:cation symporter	NA	NA	NA	NA
WP_013456216.1\|643024_644374_-	FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	1.0e-13	24.0
WP_013456029.1\|644597_646010_-\|transposase	IS1634-like element ISMbov2 family transposase	NA	NA	NA	NA
WP_115300223.1\|646467_647229_-	variable surface lipoprotein	NA	NA	NA	NA
WP_013456502.1\|647397_647697_+	PTS transporter subunit EIIB	NA	NA	NA	NA
WP_013456595.1\|647855_648764_-	BspA family leucine-rich repeat surface protein	NA	NA	NA	NA
WP_099620126.1\|648993_649314_-	hypothetical protein	NA	NA	NA	NA
WP_013456029.1\|649881_651294_-\|transposase	IS1634-like element ISMbov2 family transposase	NA	NA	NA	NA
WP_080551570.1\|651753_652782_+\|transposase	IS30-like element ISMbov1 family transposase	A0A2K9V2S9	Faecalibacterium_phage	6.5e-21	33.3

DBSCAN-SWA_5

660118 : 717294

Faecalibacterium_phage(29.41%)

transposase,integrase,tRNA

attL 693659:693686|attR 699073:699100

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080551570.1\|660118_661147_+\|transposase	IS30-like element ISMbov1 family transposase	A0A2K9V2S9	Faecalibacterium_phage	6.5e-21	33.3
WP_115266439.1\|661381_662449_+	variable surface lipoprotein	NA	NA	NA	NA
WP_013456451.1\|662487_664257_-	hypothetical protein	NA	NA	NA	NA
WP_115266440.1\|664405_665230_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_115300224.1\|665216_666191_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_115266442.1\|666256_667474_-	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	3.5e-13	32.5
WP_013455955.1\|667599_668391_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_013456065.1\|668544_668811_-	30S ribosomal protein S15	NA	NA	NA	NA
WP_013456459.1\|668901_669789_-	hypothetical protein	NA	NA	NA	NA
WP_013456636.1\|669820_670663_-	HAD family phosphatase	NA	NA	NA	NA
WP_013456468.1\|670655_671522_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_013456399.1\|671592_673959_-	membrane protein	NA	NA	NA	NA
WP_013456191.1\|673995_674958_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.5e-06	26.5
WP_013455950.1\|674938_675535_-	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_115266510.1\|676130_677159_+\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	3.8e-21	33.8
WP_115266443.1\|678017_679877_-	hypothetical protein	NA	NA	NA	NA
WP_075271156.1\|680071_680782_-	signal peptidase II	NA	NA	NA	NA
WP_115266444.1\|680783_683462_-\|tRNA	isoleucine--tRNA ligase	A0A2I2L3Y0	Orpheovirus	5.6e-80	27.4
WP_080551570.1\|683735_684764_-\|transposase	IS30-like element ISMbov1 family transposase	A0A2K9V2S9	Faecalibacterium_phage	6.5e-21	33.3
WP_013456530.1\|685235_686855_-	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	1.0e-108	39.8
WP_080551570.1\|687894_688923_-\|transposase	IS30-like element ISMbov1 family transposase	A0A2K9V2S9	Faecalibacterium_phage	6.5e-21	33.3
WP_013456106.1\|692017_693469_+	SAM-dependent DNA methyltransferase	J7I0U9	Acinetobacter_phage	3.2e-29	24.6
WP_115266445.1\|693468_694776_+	restriction endonuclease subunit S	NA	NA	NA	NA
693659:693686	attL	NA	NA	NA	NA
WP_115266510.1\|694931_695960_-\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	3.8e-21	33.8
WP_013456290.1\|696644_697442_+\|integrase	tyrosine-type recombinase/integrase	A0A0H4TI16	Erysipelothrix_phage	1.5e-20	29.3
WP_115266446.1\|697772_698831_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_115266447.1\|699836_702107_-	S8 family serine peptidase	NA	NA	NA	NA
699073:699100	attR	NA	NA	NA	NA
WP_013954662.1\|702108_703152_-	AAA family ATPase	A0A2H4UTU5	Bodo_saltans_virus	9.9e-09	29.0
WP_115266448.1\|703624_705058_+\|transposase	transposase	NA	NA	NA	NA
WP_013456032.1\|705203_707429_+	AAA family ATPase	A0A2K9V9X6	Bandra_megavirus	3.4e-30	26.6
WP_013455939.1\|708290_708953_-	ribulose-phosphate 3-epimerase	NA	NA	NA	NA
WP_013456585.1\|708939_709785_-	ribosome small subunit-dependent GTPase A	NA	NA	NA	NA
WP_013456514.1\|709796_710795_-	serine/threonine protein kinase	Q85453	Moloney_murine_sarcoma_virus	4.3e-17	32.2
WP_013456579.1\|710812_711565_-	serine/threonine-protein phosphatase	NA	NA	NA	NA
WP_013456283.1\|711570_712158_-	guanylate kinase	A0A0M5KCK5	Mollivirus	1.2e-08	38.6
WP_013456572.1\|712500_712743_+	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_013456627.1\|712745_714935_+	ribonuclease R	Q0GXV6	Lactococcus_phage	1.0e-71	33.5
WP_075270989.1\|714955_715741_+\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
WP_014829889.1\|715743_717294_+\|tRNA	methionine--tRNA ligase	A0A1V0SEZ7	Hokovirus	1.9e-80	35.7

DBSCAN-SWA_6

734015 : 833959

Faecalibacterium_phage(18.18%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080551570.1\|734015_735044_-\|transposase	IS30-like element ISMbov1 family transposase	A0A2K9V2S9	Faecalibacterium_phage	6.5e-21	33.3
WP_013954635.1\|735644_736619_-	DNA cytosine methyltransferase	R4TMW4	Halovirus	1.6e-48	38.4
WP_075271093.1\|736806_737523_-	ribonuclease HIII	NA	NA	NA	NA
WP_013954633.1\|737524_738454_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_013954632.1\|738595_741181_-	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	9.8e-90	29.6
WP_013954631.1\|741194_743111_-	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	5.7e-119	41.9
WP_075271105.1\|743214_744612_-	CvpA family protein	NA	NA	NA	NA
WP_075271109.1\|744624_745185_-	peptide deformylase	NA	NA	NA	NA
WP_013954629.1\|745252_745801_+	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	NA	NA	NA	NA
WP_075271113.1\|745801_746821_-	hypothetical protein	NA	NA	NA	NA
WP_115266515.1\|746964_748680_-	hypothetical protein	NA	NA	NA	NA
WP_013456311.1\|748790_749243_-	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_115300225.1\|749229_751071_-\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG	NA	NA	NA	NA
WP_078086175.1\|751293_752322_-\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	3.8e-21	33.8
WP_013954624.1\|752927_753377_+	hypothetical protein	NA	NA	NA	NA
WP_041309277.1\|755860_757192_+	hypothetical protein	NA	NA	NA	NA
WP_013456363.1\|757825_759259_+	hypothetical protein	NA	NA	NA	NA
WP_115266451.1\|759373_761227_-	LppA family lipoprotein	NA	NA	NA	NA
WP_013456227.1\|762020_764339_+	S8 family serine peptidase	NA	NA	NA	NA
WP_013456262.1\|764308_765733_+	hypothetical protein	NA	NA	NA	NA
WP_013456072.1\|766239_769173_+	DNA polymerase III subunit alpha	A0A2L1IZ23	Streptomyces_phage	8.8e-87	34.0
WP_115266452.1\|769174_770092_+	5'-3' exonuclease	A0A0N7ACJ6	Bacillus_phage	9.6e-32	31.2
WP_174245829.1\|770552_772154_+\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_013456376.1\|772277_774320_-	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_013456179.1\|774484_776578_-	elongation factor G	A0A1B0RXH7	Streptococcus_phage	1.8e-54	25.2
WP_013456121.1\|776607_777078_-	30S ribosomal protein S7	NA	NA	NA	NA
WP_004024001.1\|777108_777522_-	30S ribosomal protein S12	NA	NA	NA	NA
WP_013456204.1\|777842_779060_+	hypothetical protein	NA	NA	NA	NA
WP_013456632.1\|779097_780711_+	ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	2.4e-54	28.6
WP_013954980.1\|782011_782356_-	hypothetical protein	NA	NA	NA	NA
WP_115266454.1\|782487_783342_-	variable surface lipoprotein	NA	NA	NA	NA
WP_013456540.1\|783819_785208_+\|transposase	transposase	NA	NA	NA	NA
WP_013456369.1\|785642_787475_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.2e-28	25.5
WP_013456008.1\|787485_789270_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.6e-30	26.3
WP_115266455.1\|789491_790961_-	hypothetical protein	NA	NA	NA	NA
WP_115266456.1\|791441_791687_-	YneF family protein	NA	NA	NA	NA
WP_115266457.1\|791712_792801_-	M42 family peptidase	NA	NA	NA	NA
WP_174245817.1\|792873_794121_-\|transposase	IS3 family transposase	Q6H9S3	Enterobacteria_phage	3.8e-07	26.3
WP_174245830.1\|794289_795891_+\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_115266459.1\|796282_804295_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_115266460.1\|804450_808887_-	DNA-directed RNA polymerase subunit beta'	A0A076FGB9	Aureococcus_anophage	4.2e-48	23.5
WP_115266461.1\|808879_812515_-	DNA-directed RNA polymerase subunit beta	W8W1V4	Invertebrate_iridescent_virus	2.6e-48	26.8
WP_115266462.1\|812955_813618_+	hypothetical protein	NA	NA	NA	NA
WP_078086165.1\|813915_814944_+\|transposase	IS30-like element ISMbov1 family transposase	A0A2K9V2S9	Faecalibacterium_phage	6.5e-21	33.3
WP_115266463.1\|815152_815524_-	50S ribosomal protein L7/L12	NA	NA	NA	NA
WP_172792937.1\|815550_816045_-	50S ribosomal protein L10	NA	NA	NA	NA
WP_078086175.1\|816385_817414_-\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	3.8e-21	33.8
WP_115266464.1\|818071_818821_+	leucine-rich repeat protein	NA	NA	NA	NA
WP_013456485.1\|818807_820277_-\|tRNA	lysine--tRNA ligase	A0A1V0SIS0	Klosneuvirus	4.0e-80	36.9
WP_013954990.1\|820430_821321_+	hypothetical protein	NA	NA	NA	NA
WP_013456434.1\|821365_823525_+	helix-hairpin-helix domain-containing protein	NA	NA	NA	NA
WP_075271051.1\|823671_825840_+	AAA family ATPase	K4FB40	Cronobacter_phage	1.1e-107	34.4
WP_115300226.1\|827082_828327_-\|transposase	IS3 family transposase	Q6H9S3	Enterobacteria_phage	4.1e-09	27.0
WP_013954997.1\|829487_830585_+	DNA adenine methylase	M1HGA9	Paramecium_bursaria_Chlorella_virus	6.5e-27	31.6
WP_014829976.1\|830566_831508_+	DNA adenine methylase	A0A1W6JN66	Lactococcus_phage	6.5e-52	39.9
WP_013954999.1\|831646_831937_+	30S ribosomal protein S16	NA	NA	NA	NA
WP_013456497.1\|831940_832624_+\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_115266466.1\|832613_832964_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_013955000.1\|833119_833959_-\|tRNA	methionyl-tRNA formyltransferase	M4QRX9	Synechococcus_phage	9.1e-05	23.7

DBSCAN-SWA_7

858874 : 920695

Enterobacteria_phage(10.0%)

transposase,integrase,tRNA

attL 879507:879523|attR 923698:923714

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048349594.1\|858874_860119_+\|transposase	IS3 family transposase	Q6H9S3	Enterobacteria_phage	3.1e-09	27.0
WP_115300229.1\|860144_860840_-	hypothetical protein	NA	NA	NA	NA
WP_013954995.1\|860901_862146_+\|transposase	IS3 family transposase	Q6H9S3	Enterobacteria_phage	4.1e-09	27.0
WP_174245899.1\|862176_862680_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	3.2e-05	24.4
WP_115266472.1\|862887_865644_-	hypothetical protein	NA	NA	NA	NA
WP_013456522.1\|865763_866771_-	ZIP family metal transporter	NA	NA	NA	NA
WP_013456092.1\|866773_867511_-	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_013456356.1\|867513_868326_-	NAD(+) synthase	M1IPF8	Pelagibacter_phage	7.7e-33	40.0
WP_115266473.1\|868436_869342_-	hypothetical protein	NA	NA	NA	NA
WP_115266474.1\|869343_870267_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_115266475.1\|870312_871635_-	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	4.5e-67	33.4
WP_013455987.1\|871677_872577_-	ATP-binding protein	A0A0S2SXI8	Bacillus_phage	3.0e-06	28.9
WP_115266477.1\|872585_873593_-	DnaD domain protein	NA	NA	NA	NA
WP_115266478.1\|873642_874215_-	dephospho-CoA kinase	NA	NA	NA	NA
WP_115266479.1\|874216_874597_-	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	6.5e-19	46.0
WP_152028819.1\|874823_875054_+	hypothetical protein	NA	NA	NA	NA
WP_115300230.1\|875055_876180_+	site-specific DNA-methyltransferase	A0A1W6JMZ7	Lactococcus_phage	6.5e-22	29.6
WP_153700572.1\|877626_877764_+	hypothetical protein	NA	NA	NA	NA
WP_013955038.1\|877831_878008_-	hypothetical protein	NA	NA	NA	NA
WP_013955039.1\|878338_878602_-	hypothetical protein	NA	NA	NA	NA
WP_013456336.1\|878743_880024_-	ATP-binding protein	NA	NA	NA	NA
879507:879523	attL	NA	NA	NA	NA
WP_013456354.1\|880337_880961_-	ribonuclease HII	E3T5H8	Cafeteria_roenbergensis_virus	1.9e-23	35.9
WP_013456057.1\|880985_882044_-	membrane protein	NA	NA	NA	NA
WP_013955040.1\|882091_883009_-	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	7.9e-10	27.7
WP_013456176.1\|883043_883712_-	chromate transporter	NA	NA	NA	NA
WP_013455977.1\|883711_884365_-	chromate transporter	NA	NA	NA	NA
WP_013456477.1\|884371_884989_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_004024108.1\|885043_885259_-	hypothetical protein	NA	NA	NA	NA
WP_013456259.1\|885547_886159_+	DUF402 domain-containing protein	NA	NA	NA	NA
WP_013455927.1\|886455_887472_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	8.4e-37	33.6
WP_013456320.1\|887629_889303_-	ribonuclease J	NA	NA	NA	NA
WP_013455948.1\|890347_891073_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.4e-30	36.9
WP_013456583.1\|891065_891968_-	DNA polymerase III subunit delta'	NA	NA	NA	NA
WP_013456476.1\|891967_892615_-	dTMP kinase	Q2Z0N0	Pseudomonas_phage	2.2e-22	35.6
WP_013456384.1\|892629_893217_-	recombination protein RecR	NA	NA	NA	NA
WP_013456226.1\|893219_893510_-	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
WP_115266483.1\|893526_895377_-	DNA polymerase III subunit gamma/tau	E7DN81	Pneumococcus_phage	1.5e-52	38.9
WP_078086165.1\|895615_896644_-\|transposase	IS30-like element ISMbov1 family transposase	A0A2K9V2S9	Faecalibacterium_phage	6.5e-21	33.3
WP_013456015.1\|897161_897827_+	hypothetical protein	NA	NA	NA	NA
WP_115266484.1\|897956_899453_+	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	NA	NA	NA	NA
WP_115266485.1\|899455_900355_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_115266486.1\|900543_901296_+	hypothetical protein	NA	NA	NA	NA
WP_115266487.1\|901493_902027_+	hypothetical protein	NA	NA	NA	NA
WP_013456446.1\|902013_902622_+	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_115266488.1\|902680_903586_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_013955056.1\|903624_904281_-	hypothetical protein	NA	NA	NA	NA
WP_013955057.1\|904424_904937_-	adenine phosphoribosyltransferase	A0A2K9L6J1	Tupanvirus	1.0e-11	34.5
WP_115266489.1\|904965_906771_-	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	7.4e-28	24.9
WP_013456107.1\|906749_907052_-	YlxR family protein	NA	NA	NA	NA
WP_115266490.1\|907035_908670_-	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_101456728.1\|908677_909124_-	ribosome assembly cofactor RimP	NA	NA	NA	NA
WP_115266491.1\|909263_909836_-	thymidine kinase	Q6GYZ9	Mycoplasma_phage	2.1e-69	69.5
WP_013456539.1\|909911_911282_-	peptidase M17	Q6GYZ8	Mycoplasma_phage	1.5e-153	73.1
WP_115266518.1\|911714_912743_+\|transposase	IS30 family transposase	A0A2K9V2S9	Faecalibacterium_phage	8.5e-21	33.3
WP_115266492.1\|912968_913976_+	ECF transporter S component	NA	NA	NA	NA
WP_115266494.1\|914522_915119_+	variable surface lipoprotein	NA	NA	NA	NA
WP_115287432.1\|917381_918044_+	variable surface lipoprotein	NA	NA	NA	NA
WP_115300232.1\|918253_918853_+	variable surface lipoprotein	NA	NA	NA	NA
WP_115287438.1\|918895_919660_-	variable surface lipoprotein	NA	NA	NA	NA
WP_013456123.1\|919945_920695_+\|integrase	site-specific integrase	NA	NA	NA	NA
923698:923714	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: NZ_CP022593.1|WP_013955038.1|877831_878008_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP022593.1|WP_013955038.1|877831_878008_-|hypothetical-protein

877831_878008_-

58 aa aa

858874-920695

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP022593_3	Orphan	3.1\|624118\|53\|NZ_CP022593\|CRISPRCasFinder	624118-624170	53	895553-895501	2

1. spacer 3.1|624118|53|NZ_CP022593|CRISPRCasFinder matches to NZ_CP022593 position: 895553-895501, mismatch: 2

ttttttattcttttggctattctcttgtcagaaccaccaaaaattggtattat	CRISPR spacer
ttttttattcttttagccattctcttgtcagaaccaccaaaaattggtattat	Protospacer
**************.**.***********************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP022593

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information