CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP029629	Staphylococcus aureus strain MOK063 chromosome, complete genome	8 crisprs	csa3,DEDDh,cas3,DinG,WYL	5	2	11	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP029629_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP029629_1

721800-721889

Orphan

Consensus_repeat	Method
TGATTGAGAAGTCAGTCGAAAAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP029629_1

>merge|NZ_CP029629|1|721800-721889|CRISPRCasFinder
TGATTGAGAAGTCAGTCGAAAAACTATTGCAAAAGAAAAACGATTATGTATAATAAAGTTATAAATTGATTGAGAAGTCAGTCAAAAACG

>NZ_CP029629|1|1|721800-721889|CRISPRCasFinder
TGATTGAGAAGTCAGTCGAAAAAC	TATTGCAAAAGAAAAACGATTATGTATAATAAAGTTATAAAT
TGATTGAGAAGTCAGTCAAAAACG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP029629.1\|WP_000695071.1\|722787_723171_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029629.1\|WP_000867940.1\|713657_714443_-\|carbon-nitrogen-family-hydrolase	unknown	unknown	gnl\|CDD\|143607
NZ_CP029629.1\|WP_070046546.1\|719872_721045_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP029629.1\|WP_000481967.1\|722128_722446_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|200128
NZ_CP029629.1\|WP_000522384.1\|714803_715430_-\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|226090
NZ_CP029629.1\|WP_000917289.1\|717827_718112_+\|co-chaperone-GroES	unknown	unknown	gnl\|CDD\|178988
NZ_CP029629.1\|WP_001103965.1\|723171_723498_+\|DUF1474-family-protein	unknown	unknown	gnl\|CDD\|369323
NZ_CP029629.1\|WP_001002725.1\|723562_724432_+\|primase-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|214926
NZ_CP029629.1\|WP_000240645.1\|718187_719804_+\|chaperonin-GroEL	unknown	unknown	gnl\|CDD\|234573
NZ_CP029629.1\|WP_001549197.1\|712927_713062_+\|delta-lysin-family-phenol-soluble-modulin	unknown	unknown	gnl\|CDD\|173213
NZ_CP029629.1\|WP_070001967.1\|724445_726155_+\|DUF927-domain-containing-protein	unknown	unknown	gnl\|CDD\|227806
NZ_CP029629.1\|WP_000120323.1\|715625_716885_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236768
NZ_CP029629.1\|WP_000784889.1\|722442_722598_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029629.1\|WP_001105707.1\|712122_712692_-\|accessory-gene-regulator-AgrB	unknown	unknown	gnl\|CDD\|214819
NZ_CP029629.1\|WP_000620856.1\|721058_721733_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188
NZ_CP029629.1\|WP_001231374.1\|722582_722786_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029629.1\|WP_001019789.1\|726843_727485_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374630
NZ_CP029629.1\|WP_000153640.1\|721905_722124_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NZ_CP029629.1\|WP_000197635.1\|716909_717653_-\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP029629.1\|WP_000356933.1\|726466_726847_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP029629.1\|WP_000867940.1\|713657_714443_-\|carbon-nitrogen-family-hydrolase	gnl\|CDD\|143607	cd07583, nitrilase_5, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	7.8671e-127
NZ_CP029629.1\|WP_070046546.1\|719872_721045_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	3.07439e-48
NZ_CP029629.1\|WP_000481967.1\|722128_722446_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|200128	TIGR01764, Probable_excisionase, DNA binding domain, excisionase family. An excisionase, or Xis protein, is a small protein that binds and promotes excisive recombination; it is not enzymatically active. This model represents a number of putative excisionases and related proteins from temperate phage, plasmids, and transposons, as well as DNA binding domains of other proteins, such as a DNA modification methylase. This model identifies mostly small proteins and N-terminal regions of large proteins, but some proteins appear to have two copies. This domain appears similar, in both sequence and predicted secondary structure (PSIPRED) to the MerR family of transcriptional regulators (pfam00376). [Unknown function, General].	5.89089e-17
NZ_CP029629.1\|WP_000522384.1\|714803_715430_-\|nitroreductase-family-protein	gnl\|CDD\|226090	COG3560, FMR2, Predicted oxidoreductase related to nitroreductase [General function prediction only].	5.71771e-116
NZ_CP029629.1\|WP_000917289.1\|717827_718112_+\|co-chaperone-GroES	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	5.94304e-45
NZ_CP029629.1\|WP_001103965.1\|723171_723498_+\|DUF1474-family-protein	gnl\|CDD\|369323	pfam07342, DUF1474, Protein of unknown function (DUF1474). This family consists of several bacterial proteins of around 100 residues in length. Members of this family seem to be found exclusively in Staphylococcus aureus. The function of this family is unknown.	3.47781e-22
NZ_CP029629.1\|WP_001002725.1\|723562_724432_+\|primase-C-terminal-domain-containing-protein	gnl\|CDD\|214926	smart00942, PriCT_1, Primase C terminal 1 (PriCT-1). This alpha helical domain is found at the C terminal of primases.	2.31563e-15
NZ_CP029629.1\|WP_000240645.1\|718187_719804_+\|chaperonin-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NZ_CP029629.1\|WP_001549197.1\|712927_713062_+\|delta-lysin-family-phenol-soluble-modulin	gnl\|CDD\|173213	PRK14752, PRK14752, delta-lysin family phenol-soluble modulin.	8.25732e-15
NZ_CP029629.1\|WP_070001967.1\|724445_726155_+\|DUF927-domain-containing-protein	gnl\|CDD\|227806	COG5519, COG5519, Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair].	2.37856e-165
NZ_CP029629.1\|WP_000120323.1\|715625_716885_+\|hypothetical-protein	gnl\|CDD\|236768	PRK10819, PRK10819, transport protein TonB; Provisional.	1.8239e-10
NZ_CP029629.1\|WP_001105707.1\|712122_712692_-\|accessory-gene-regulator-AgrB	gnl\|CDD\|214819	smart00793, AgrB, Accessory gene regulator B. The accessory gene regulator (agr) of Staphylococcus aureus is the central regulatory system that controls the gene expression for a large set of virulence factors. The arg locus consists of two transcripts: RNAII and RNAIII. RNAII encodes four genes (agrA, B, C, and D) whose gene products assemble a quorum sensing system. At low cell density, the agr genes are continuously expressed at basal levels. A signal molecule, autoinducing peptide (AIP), produced and secreted by the bacteria, accumulates outside of the cells. When the cell density increases and the AIP concentration reaches a threshold, it activates the agr response, i.e. activation of secreted protein gene expression and subsequent repression of cell wall-associated protein genes. AgrB and AgrD are essential for the production of the autoinducing peptide which functions as a signal for quorum sensing. AgrB is a transmembrane protein. AgrB is involved in the proteolytic processing of AgrD and may have both proteolytic enzyme activity and a transporter facilitating the export of the processed AgrD peptide.	4.40383e-47
NZ_CP029629.1\|WP_000620856.1\|721058_721733_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.74531e-10
NZ_CP029629.1\|WP_001019789.1\|726843_727485_+\|hypothetical-protein	gnl\|CDD\|374630	pfam16560, SAPI, Putative mobile pathogenicity island. SAPI is a family of putative Gram-positive mobile pathogenicity island proteins. SAPIs are responsible for many superantigen-related diseases in humans as they carry two or more superantigens.	4.9645e-115
NZ_CP029629.1\|WP_000153640.1\|721905_722124_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	9.85461e-11
NZ_CP029629.1\|WP_000197635.1\|716909_717653_-\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.67124e-11

>NZ_CP029629.1|WP_000620856.1|721058_721733_-|helix-turn-helix-transcriptional-regulator
MIRNRLSELLSERGLKISRVAKDVKIARSSLTSMAQNDSEMIRYDAIDKLCSYLHISPSEFFEHNPINFDFTFDEEPNYKINDVFEGFEVTANITHAFSIENFDFEILVDVELDNRQKLNFDLDVSYKETEKITNSQHRFIFTIKNEDENIGLKKYVDSLSAGLKNLLFKKINQKLSGYVSEIIVKNIDDIEELFPNKGEKCTTLHKEILQTDSRLSSDLFKEY
>NZ_CP029629.1|WP_070046546.1|719872_721045_-|tyrosine-type-recombinase/integrase
MASYEKRGNTWRYRISLGKDAETGKYKYISNSGFKRKSDAKHHAEMVERQLRNGEYIAPSTSTFKQVANDWLKQYANEVKVSSVRAREKAIHHAIERFNYKPIQTINKHEYQRFVNDISAQYSKNYVDSIIASTNMIFKYAYDMKLIRILPSEGIKRPKKKVSVEELEDTEIYKKFLEKDELFQFLEIAKNHHSPQNSFEVFCTLAYTGMRAGELLALKWSDIDFENNTINITKTYYNPNNNKKQYQILTPKTESSIGKIPVDPHVIKLLKNYKVDVQDTWKNELYVDNNFVFTDVNGYPLVIKKLQLWIKAILKKTDITNKQISTHSFRHTHCALLIEAGVHIKEIQERLRHKDINTTMNIYAKITNSYKKDASQKFSKLMENVSKDLF
>NZ_CP029629.1|WP_000240645.1|718187_719804_+|chaperonin-GroEL
MVKQLKFSEDARQAMLRGVDQLANAVKVTIGPKGRNVVLDKEFTAPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGLRQGIDKAVKVAVEALHENSQKVENKNEIAQVGAISAADEEIGRYISEAMEKVGNDGVITIEESNGLNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYILVTDKKISSFQDILPLLEQVVQSNRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGAQVITDDLGLDLKDASIDMLGTASKVEVTKDNTTVVDGDGDENSIDARVSQLKSQIEETESDFDREKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVNVYQKVSEIEAEGDIETGVNIVLKALTAPVRQIAENAGLEGSVIVERLKNAEPGVGFNAATNEWVNMLEEGIVDPTKVTRSALQHAASVAAMFLTTEAVVASIPEKNNDQPNMGGMPGMM
>NZ_CP029629.1|WP_000917289.1|717827_718112_+|co-chaperone-GroES
MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGTGRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
>NZ_CP029629.1|WP_000197635.1|716909_717653_-|CPBP-family-intramembrane-metalloprotease
MTRLWASLLTVIIYILSQFLPLLIVKKLPFVQYSGIELTKAVIYIQLVLFLIAATTIILINLKIKNPTKLELEVKEPKKYIIPWALLGFALVMIYQMVVSIVLTQIYGGQQVSPNTEKLIIIARKIPIFIFFVSIIGPLLEEYVFRKVIFGELFNAIKGNRIVAFIIATTVSSLIFALAHNDFKFIPVYFGMGVIFSLAYVWTKRLAVPIIIHMLQNGFVVIFQLLNPEALKKATEQANFIYHIFIP
>NZ_CP029629.1|WP_000120323.1|715625_716885_+|hypothetical-protein
MSYHWFKKMLLSTSILILSSSSLGLATYTVEAKDNLNGEKPTTNLNHNITSPSVNSEMNNNETGTPHESNQTGNEGTGSNSRDANPDSNNVKPDSNNQNPSTDSKPDPNNQNPSPNPKPDPDNPKPKPDPKPDPDKPKPNPDPKPDPDNPKPNPDPKPDPDKPKPNPDPKPDPDKPKPNPNPKPDPNKPNPNPSPDPDQHGDSNHSGGSKNGGTWNPNASDGSNQGQWQPNGNQGNSQNPTGNDFVSQRFLALANGAYKYNPYILNQINKLGKDYGEVTDEDIYNIIRKQNFSGNAYLNGLQQQSNYFRFQYFNPLKSERYYRNLDEQVLALITGEIGSMPDLKKPEDKPDSKQRSFEPHEKDDFTVVKKQEDNKKSASTAYSKSWLAIVCSMMVVFSIMLFLFVKRNKKKNKNESQRR
>NZ_CP029629.1|WP_000522384.1|714803_715430_-|nitroreductase-family-protein
MGLFKKDKKAMTFDNAMEERRSIYNLKDSISISDDELESMIAHAVKHVPSSFNSQSTRIVLLLNDNNNKFWDNTKAILKEVMGENRDFEPTEQKIDNFKHSYGTILFYEDQDVVSGLQEQMPNYYDNFAIWSTQTNAMHQFAIWTALATKGIGASLQHYNPLVDEMTSNEFNIPKSWKLIAQMPFGDIREAAGEKTFNPVEDRFVIKK
>NZ_CP029629.1|WP_000867940.1|713657_714443_-|carbon-nitrogen-family-hydrolase
MKVQIYQLPIIFGDSSKNEAQITQWFEKNMNAEVDVVVLPEMWNNGYDLEHLNEKADNNLGQSFSFIKHLAEKYKVDIVAGSVSNIRNNQIFNTAFSVNKSGQLINEYDKVHLVPMLREHEFLTAGENVAEPFQLSDGTYVTQLICYDLRFPELLRYPARSGAKIAFYVAQWPMSRLQHWHSLLKARAIENNMFVIGTNSTGFDGNTEYAGHSIVINPNGDLVGELNESADILTVDLNLNEVEQQRENIPVFKSIKLDLYK
>NZ_CP029629.1|WP_001549197.1|712927_713062_+|delta-lysin-family-phenol-soluble-modulin
MSCLILRIFILIKEGVISMAQDIISTIGDLVKWIIDTVNKFTKK
>NZ_CP029629.1|WP_001105707.1|712122_712692_-|accessory-gene-regulator-AgrB
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQVLAKNIGKLIVMYTIAYILNIFLFTLITNLTFYLIRRHAHGAHAPSSFWCYVESIILFILLPLVIVNFHINFLIMIILTVISLGVISVYAPAATKKKPIPVRLIKRKKYYAIIVSLTLFIITLIIKEPFAQFIQLGIIIEAITLLPIFFIKEDLK
>NZ_CP029629.1|WP_000153640.1|721905_722124_+|helix-turn-helix-transcriptional-regulator
MTILANTRKFKEAMFLKGFNLSDLSRETGVGISYLSQIINGKKIPSPKLAKKMAEVLQVEVNELFEFEVKEA
>NZ_CP029629.1|WP_000481967.1|722128_722446_+|helix-turn-helix-domain-containing-protein
MFNINIDEDEARELLEQAINARVDELAKEKYFMTYKELSNYLNLSKPTIEELLINNGMKYYMVGSTYRFKKSDVDEFMEQLTAHMNIQNNDFKQVNIKKLLEARQ
>NZ_CP029629.1|WP_000784889.1|722442_722598_+|hypothetical-protein
MKMYLTYICLVSLLTILLLAISNMYVAFSVYGMMITYGFNLTGEITTCENK
>NZ_CP029629.1|WP_001231374.1|722582_722786_+|hypothetical-protein
MRKQVIITKTVVGWYNIKDTQHNLMLNIPPKVFEHYFPDVSKDVQVACLEMDLSKITEIKNKKKVGS
>NZ_CP029629.1|WP_000695071.1|722787_723171_+|hypothetical-protein
MKIKQKYQLSKVVKILEVVLYEEDKFQSDKDYHYQDKAFYEYALKLVHNGLFNILAELDFEDEVFLILDEVTMTLSDVMKETQHVYRYSVIDEKGEHKHTTDRKGHVIGMLEWALDYIVGNIEVEVL
>NZ_CP029629.1|WP_001103965.1|723171_723498_+|DUF1474-family-protein
MNWEINDLFSDLKLLKDRFEDLKDNHGWHFEELYPHEPNHNLNKDELIREGASYHERRIHNNQMFDLFHLYIEQFDKIIEKFHEIEKASSENFGEESDDAKNSIKVAE
>NZ_CP029629.1|WP_001002725.1|723562_724432_+|primase-C-terminal-domain-containing-protein
MNEIKLEYDTHVSVVHYESLDSRSFNSFSKPKWSKLVNKLSVPIEANYKYARGVAVYGDIKDGANDHGEIIKKHRNDVNVVYRDVIVLDYDEINDLKQLHEAISSALSNVAWFWHTSYSHRTEQARIRLYIPLNERISADDYRKYSKVLANKIGHKVDEGSYQPSRCFALPVIQKGHIFIKRVNDCPIIDVDMLEQWSKELEQSNASPNVIGYTRRDSAYWRELSFGTTEGNRNNALASLVGHLLRCRVNDYIVYSYALLWGQFACKPPMKEQEINATFQSILNKHYNN
>NZ_CP029629.1|WP_070001967.1|724445_726155_+|DUF927-domain-containing-protein
METGKSDVLDKIEKINKKDSALQEIIPKGYEIEHHQCGVALYQLIPSKKEGEPDKKVFITNTIPQITERFEDIESNEVSFNMLFYDNKTPVNIAVSAEEISDSRQLLKLVNKKLDVTSSTSTKLVDYINVSKRYNPPLNVKVATRLGHVKGYFIYPYQEVMKDSNIKLFSNDKGFQKLIDSFQSKGTLEGYSKKVFGQIKDLPMVMVMLYASLGSVLLRGFGLQPFIVEISGSTSTGKTFTLNLVSSVWGTSDLITTWSSTQNSIESMASFLNSFPMFKDDTRNTHPKFVTSATYNFSSGESKSRSNINLTLNAKKEWRNILISTGESSIANMADEKAGVSARVVTLQDQPYPDNFDFTTLDKSFRENYGTLGLAFIKQYESKKDVYKNAFESYQRYFNQKGSNEIMQCLGRAFALLQVTGEVLNDIDGFEHDHFKIIEQAYDSMVKNNKTIDKPKQLLEELLQYLDANRNNIAGDGYSSVKNGDIKAIYKRDYLCILGQTVHDKLGHEMQTITGQWGKKGYLIKGEKDRLQKKVSHKNIKYRGFAINKEMLEELGFDFSNSHNPYSDY
>NZ_CP029629.1|WP_000356933.1|726466_726847_+|hypothetical-protein
MDKEQLKKYIYDYVKEYKEIPIYQLEDLFKEMNHDYIGRTSITHDKDENVVFWSGWNKITMFALIELVKSEQLDLVYRGSYVMRYLLDGRVPNLPLAICYPEDGQQTDVPSWVPMVLRINKEEKIK
>NZ_CP029629.1|WP_001019789.1|726843_727485_+|hypothetical-protein
MNIETIVNQFETRAGTLLRYYTGLLESSRETHFAFKIYNDPFDMVYVMMKGKLYGHVYIQDCKVRQSFELASPKHTEGLIRSIERHYVGYELHDGKQLSISDMMASQLFEDEYFMYGLQTYAESNNSDVFEYLENGFDTDTLEGIQSSNTDVISNIEMLYQIATGINEPEPELVEGLRLVTEFVQDENATQEDYKALERKLNDLKASYYSLSK

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Crispr_ID: NZ_CP029629_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP029629_2

1015997-1016081

Orphan

Consensus_repeat	Method
CCCACCCCAACTTGCATGGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP029629_2

>merge|NZ_CP029629|2|1015997-1016081|CRISPRCasFinder
CCCACCCCAACTTGCATGGTCTGTAGAATTTCTTTTCGAAATTCTCTATGTTGGGGCCCCACCCCAACTTGCATTGTCTGTAGAA

>NZ_CP029629|2|2|1015997-1016081|CRISPRCasFinder
CCCACCCCAACTTGCATGGTCTGTAGAA	TTTCTTTTCGAAATTCTCTATGTTGGGGC
CCCACCCCAACTTGCATTGTCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP029629.1\|WP_000123164.1\|1032399_1033668_+\|NADP-dependent-isocitrate-dehydrogenase	unknown	unknown	gnl\|CDD\|180792
NZ_CP029629.1\|WP_000161674.1\|1011752_1012808_-\|aminopeptidase-P-family-protein	unknown	unknown	gnl\|CDD\|223085
NZ_CP029629.1\|WP_110161672.1\|1025437_1027195_+\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235784
NZ_CP029629.1\|WP_000277601.1\|1013976_1014390_-\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP029629.1\|WP_000626076.1\|1016344_1017286_+\|pApA-hydrolase-Pde2	unknown	unknown	gnl\|CDD\|223691
NZ_CP029629.1\|WP_000777190.1\|1012982_1013672_+\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|234811
NZ_CP029629.1\|WP_000058389.1\|1020953_1022183_+\|NAD-dependent-malic-enzyme-4	unknown	unknown	gnl\|CDD\|235976
NZ_CP029629.1\|WP_000634175.1\|1009677_1010178_-\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP029629.1\|WP_000818525.1\|1029520_1030882_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NZ_CP029629.1\|WP_001789984.1\|1011560_1011659_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029629.1\|WP_000160433.1\|1014594_1015893_+\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|226594
NZ_CP029629.1\|WP_000840584.1\|1007194_1008142_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|223897
NZ_CP029629.1\|WP_000829167.1\|1031229_1032351_+\|citrate-synthase	unknown	unknown	gnl\|CDD\|184468
NZ_CP029629.1\|WP_000717561.1\|1024447_1025416_+\|6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111
NZ_CP029629.1\|WP_000136253.1\|1006577_1007072_+\|thiol-peroxidase	unknown	unknown	gnl\|CDD\|179055
NZ_CP029629.1\|WP_000471571.1\|1022377_1023235_+\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	unknown	unknown	gnl\|CDD\|235547
NZ_CP029629.1\|WP_000689998.1\|1010318_1011437_+\|alanine-dehydrogenase	unknown	unknown	gnl\|CDD\|240630
NZ_CP029629.1\|WP_110161671.1\|1008229_1009432_+\|acetate-kinase	unknown	unknown	gnl\|CDD\|234680
NZ_CP029629.1\|WP_001836688.1\|1017306_1020504_+\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|223660
NZ_CP029629.1\|WP_000883648.1\|1023234_1024179_+\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	unknown	unknown	gnl\|CDD\|235580

Protein	Function_ID	Function_description	E-value
NZ_CP029629.1\|WP_000123164.1\|1032399_1033668_+\|NADP-dependent-isocitrate-dehydrogenase	gnl\|CDD\|180792	PRK07006, PRK07006, isocitrate dehydrogenase; Reviewed.	0
NZ_CP029629.1\|WP_000161674.1\|1011752_1012808_-\|aminopeptidase-P-family-protein	gnl\|CDD\|223085	COG0006, PepP, Xaa-Pro aminopeptidase [Amino acid transport and metabolism].	9.25455e-126
NZ_CP029629.1\|WP_000277601.1\|1013976_1014390_-\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	7.63781e-19
NZ_CP029629.1\|WP_000626076.1\|1016344_1017286_+\|pApA-hydrolase-Pde2	gnl\|CDD\|223691	COG0618, COG0618, Exopolyphosphatase-related proteins [General function prediction only].	2.09048e-98
NZ_CP029629.1\|WP_000777190.1\|1012982_1013672_+\|metal-dependent-hydrolase	gnl\|CDD\|234811	PRK00685, PRK00685, metal-dependent hydrolase; Provisional.	1.10209e-133
NZ_CP029629.1\|WP_000058389.1\|1020953_1022183_+\|NAD-dependent-malic-enzyme-4	gnl\|CDD\|235976	PRK07232, PRK07232, bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed.	0
NZ_CP029629.1\|WP_000634175.1\|1009677_1010178_-\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	9.27306e-36
NZ_CP029629.1\|WP_000818525.1\|1029520_1030882_-\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	0
NZ_CP029629.1\|WP_000840584.1\|1007194_1008142_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|223897	COG0827, COG0827, Adenine-specific DNA methylase [DNA replication, recombination, and repair].	1.04193e-56
NZ_CP029629.1\|WP_000160433.1\|1014594_1015893_+\|CBS-domain-containing-protein	gnl\|CDD\|226594	COG4109, COG4109, Predicted transcriptional regulator containing CBS domains [Transcription].	0
NZ_CP029629.1\|WP_110161672.1\|1025437_1027195_+\|pyruvate-kinase	gnl\|CDD\|235784	PRK06354, PRK06354, pyruvate kinase; Provisional.	0
NZ_CP029629.1\|WP_000829167.1\|1031229_1032351_+\|citrate-synthase	gnl\|CDD\|184468	PRK14035, PRK14035, citrate synthase; Provisional.	0
NZ_CP029629.1\|WP_000717561.1\|1024447_1025416_+\|6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	0
NZ_CP029629.1\|WP_000136253.1\|1006577_1007072_+\|thiol-peroxidase	gnl\|CDD\|179055	PRK00522, tpx, thiol peroxidase.	8.69777e-99
NZ_CP029629.1\|WP_000471571.1\|1022377_1023235_+\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	gnl\|CDD\|235547	PRK05654, PRK05654, acetyl-CoA carboxylase carboxyltransferase subunit beta.	0
NZ_CP029629.1\|WP_000689998.1\|1010318_1011437_+\|alanine-dehydrogenase	gnl\|CDD\|240630	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains. Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.	0
NZ_CP029629.1\|WP_110161671.1\|1008229_1009432_+\|acetate-kinase	gnl\|CDD\|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	0
NZ_CP029629.1\|WP_001836688.1\|1017306_1020504_+\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|223660	COG0587, DnaE, DNA polymerase III, alpha subunit [DNA replication, recombination, and repair].	0
NZ_CP029629.1\|WP_000883648.1\|1023234_1024179_+\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	gnl\|CDD\|235580	PRK05724, PRK05724, acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated.	0

>NZ_CP029629.1|WP_000160433.1|1014594_1015893_+|CBS-domain-containing-protein
MTKHEQILDYIESLSIGSKISVRKIAKFLNVSEGTAYRAIKDADKMGMVATIDRVGTVRIEKRNRNEIEHLTFNEIVNIIDGQVLGGNKGITKMVSKFAIGAMELKDILKYIGPKTLLIVGNREDVQIEALKRGTAILITGGFKPSNKVINFANEHDLPVLSSSYDTFLVANIINKALFNQKIRKDILIVQDIMTPLDDLSVLFDTMKIADYKRMANRTGHTRFPVVNESYKLVGIVTSREMINTKDDDEIDKVMTRNPIYVNAMSTVASCAHMMIWEGIELIPVVSSNKKTVGVINRQDVLKSMQLLGRQPQMGETINDQIAKYITMNQDGITVEVSPLLINHYGTVSKAAFVSIIEETIQYEMRKFKKGNAMIENLNIVYIKTVPIESHITVRFGILDVGRNFAKIEVNMHSQNDKVASALVICQMFDEV
>NZ_CP029629.1|WP_000277601.1|1013976_1014390_-|universal-stress-protein
MYKNILLGVDTQLKNEKALKEVSKLAGEGTVVTVLNAISEQDAQASIKAGVHLNKLTEERNKRLEKTRKALEDYGIDYDQIIVRGNAKEELLKHANSGKYEIVVLSNRKAEDKKKFVLGSVSHKVAKRATIPVLIVK
>NZ_CP029629.1|WP_000777190.1|1012982_1013672_+|metal-dependent-hydrolase
MKLSFHGQSTIYLEGNNKKVIVDPFISNNPKCDLNIETVQVDYIVLTHGHFDHFGDVVELAKKTGATVIGSAEMADYLSSYHGVENVHGMNIGGKVNFDFGSVKFVQAFHSSSFTHENGIPVYLGMPMGIVFEVEGKTIYHTGDTGLFSDMSLIAKRHPVDVCFVPIGDNFTMGIDDASYAINEFIKPKISVPIHYDTFPLIEQDPQQFKDAVNVGDVQILKPGESVQF
>NZ_CP029629.1|WP_000161674.1|1011752_1012808_-|aminopeptidase-P-family-protein
MTKISKIIDELNNQQADAAWITTPLNVYYFTGYRSEPHERLFALLIKKDGKQVLFCPKMEVEEVKASPFTGEIVGYLDTENPFSLYPQTINKLLIESEHLTVARQKQLTSGFNVNSFGDVDLTIKQLRNIKSEDEISKIRKAAELADKCIEIGVSYLKEGVTEREVVNHIEQTIKQYGVNEMSFDTMVLFGDHAASPHGTPGDRRLKSNEYVLFDLGVIYEHYCSDMTRTIKFGEPSKEAQEIYNIVLEAETSAIQAIKPGIPLKDIDHIARNIILEKGYGEYFPHRLGHGLGLQEHEYQDVSSTNSNLLEAGMVITIEPGIYVPGVAGVRIEDDILVTNEGYEVLTHYEK
>NZ_CP029629.1|WP_001789984.1|1011560_1011659_+|hypothetical-protein
MNDIDLIHYMLLMNIPAYVFLACLLHIAFRLG
>NZ_CP029629.1|WP_000689998.1|1010318_1011437_+|alanine-dehydrogenase
MKIGIPREIKNNENRVGLSPSGVHALVESGHTVLVETNAGSGSFFEDVDYKEAGAEIVAEQAKVWDVDMVIKVKEPLESEYPYFKEGLVLFTYLHLANEEKLTQALIDRKVISIAYETVQLPDRSLPLLSPMSEVAGRMSAQVGAEFLQKLNGGMGILLGGVPGVPKGKVTIIGGGQAGTNAAKIALGLGADVTILDVNPKRLQQLDDLFGGRVHTIMSNPLNIELYVKQSDLVIGAVLIPGAKAPRLVTEDMIKQMKNGSVIIDIAIDQGGIFETTDKITTHDDPTYIKHGVVHYAVANMPGAVPRTSTLALNNATLPYALMLANKGYREAFKSNQPLSLGLNTYKGHVTNKGVAEAFEMEYKSVEEALQL
>NZ_CP029629.1|WP_000634175.1|1009677_1010178_-|universal-stress-protein
MITYKNILIAVDGSHEAEWAFNRAVGVAKRNDAKLTIVNVIDSRTYSSYEVYDAQFTEKSKHFAEELLNGYKEVATNAGVKDVETRLEFGSPKSIIPKKLAHEINADLIMSGTSGLNAVERFIVGSVSESIVRHAPCDVLVVRTEELPADFQPQVATTQLREKYQN
>NZ_CP029629.1|WP_110161671.1|1008229_1009432_+|acetate-kinase
MSKLILAINAGSSSLKFQLIRMPEEELVTKGLIERIGLKDSIFTIEVNGEKVKTVQDIKDHVEAVDIMLDAFKAHNIINDINDIDGTGHRVVHGGEKFPESVAITDEVEKEIEELSELAPLHNPANLMGIRAFRKLLPNIPHVAIFDTAFHQTMPEKAYLYSLPYHYYKDYGIRKYGFHGTSHKFVSQRAAEMLDKPIEDLRIISCHIGNGASIAAIDGGKSIDTSMGFTPLAGVTMGTRSGNIDPALIPFIMEKTGKTAEQVLEILNKESGLLGLSGTSSDLRDLSEEAESGKARSQMALDVFASKIHKYIGSYAARMHGVDVIVFTAGIGENSVEIRAKVLEGLEFMGIYWDPKKNENLLRGKEGFINYPHSPVKVVVIPTDEESMIARDVMTFGGLK
>NZ_CP029629.1|WP_000840584.1|1007194_1008142_+|class-I-SAM-dependent-methyltransferase
MAEQQTIMERLFHTLDEKAKTLNNENGQSFIENLGLAMEQVYTNERGLLEQSTLQDRRKAFQFAYLSLMQEEKIQANHQITPDSIGLILGFLVERFMNNQEELHIVDIASGAGHLSATVKEVLPEIAVMHHLIEVDPVLSRVSVHLANFLEIPFDVYPQDAIMPLPLEEIDIVIGDFPVGYYPIDERSKEFKLGFEEGHSYSHYLLIEQAINVLKDAGYAFLVVPSNIFTGEHVKQLEKYIATETEMQAFLNLPPTLFKNEKARKSILILQKKKSGETKPVEVLLANIPDFKNPSQFQGFMTELNQWMDTNRPKK
>NZ_CP029629.1|WP_000136253.1|1006577_1007072_+|thiol-peroxidase
MTEITFKGGPIHLKGQQINEGDFAPDFTVLDNDLNQVTLADYAGKKKLISVVPSIDTGVCDQQTRKFNSDASKEEGIVLTISADLPFAQKRWCASAGLDNVITLSDHRDLSFGENYGVVMEELRLLARAVFVLDADNKVVYKEIVSEGTDFPDFDAALAAYKNI
>NZ_CP029629.1|WP_000626076.1|1016344_1017286_+|pApA-hydrolase-Pde2
MISTLNEIMKCIEDNDTIIIHRHVRPDPDAYGSQLGLKYYIQQKFPQKQVFAVGEAESSLSFIGELDNIDDKTYQDALVIVCDTANAPRIDDERYSTGRKLIKIDHHPAVDQYGDINLVNTNASSTSEIIYDLISHFNDEAIVNKDIASVLYLGIVGDTGRFLFNNTSEHTMEIAGKLIGHDIDHNALLNKMMEKDPKMLPFQGYVLQHFELMDDGFCQVKITEDVLEQFGIQPNEASQFVNTIADIKGLKIWVFAVDEGSEIRCRLRSKGQLIINDIAQDFGGGGHPNASGVSVDSWDEFEQLATALRTKLN
>NZ_CP029629.1|WP_001836688.1|1017306_1020504_+|DNA-polymerase-III-subunit-alpha
MVAYLNIHTAYDLLNSSLKIEDAVRLAVSENVDALAITDTNVLYGFPKFYDACIANNIKPIFGMTIYVTNGLNTVETVVLAKNNDGLKDLYQLSSEIKMNALEHVSFELLKRFSNNMIIIFKKVGDQHRDIVQVFETHNDTYMDHLSISIQGRKHVWIQDVCYQTRQDADTISALAAIRDNTKLDLIHDQEDFGAHFLTEKEVNQLDINQEYLTQVDVIAQKCNAELKYHQSLLPQYETPNDESAKKYLWRVLVTQLKKLELNYDVYLERLKYEYKVITNMGFEDYFLIVSDLIHYAKTNDVMVGPGRGSSAGSLVSYLLGITTIDPIKFNLLFERFLNPERVTMPDIDIDFEDTRRERVIQYVQEKYGELHVSGIVTFGHLLARAVARDVGRIMGFDEVTLNEISSLIPHKLGITLDEAYQIDDFKKFVHRNHRHERWFSICKKLEGLPRHTSTHAAGIIINDHPLYEYAPLTKGDTGLLTQWTMTEAERIGLLKIDFLGLRNLSIIHQILTQVKKDLGINIDIEKIPFDDQKVFELLSQGDTTGIFQLESDGVRSVLKKLKPEHFEDIVAVTSLYRPGPMEEIPTYITRRHDPSKVQYLHPHLEPILKKTYGVIIYQEQIMQIASTFANFSYGEADILRRAMSKKNRAVLESERQHFIEGAKQNGYHEDISKQIFDLILKFADYGFPRAHAVSYSKIAYIMSFLKVHYPNYFYANILSNVIGSEKKTAQMIEEAKKQGITILPPNINESHWFYKPSQKGIYLSIGTIKGVGYQSVKVIVDERYQNGKFKDFFDFARRIPKRVKTRKLLEALILVGAFDAFGKTRSTLLQAIDQVLDGDLNIEQDGFLFDILTPKQMYEDKEELPDALISQYEKEYLGFYVSQHPVDKKFVAKQYLTIFKLSNAQNNKPILVQFDKVKQIRTKNGQNMAFVTLNDGIETLDGVIFPNQFKKYEELLSHNDLFIVSGKFDHRKQQRQLIINEIQTLATFEEQKLAFAKQIIIRNKSQIDMFEEMIKATKENANDVMLSFYDETIKQMTTLGYINQKDSMFNNFIQSFNPSDIRLI
>NZ_CP029629.1|WP_000058389.1|1020953_1022183_+|NAD-dependent-malic-enzyme-4
MSLRDEALEMHKRNQGKLEVKPNVKVTNKEELSLAYSPGVAEPCKDIYEDKRKVYDYTIKGNTVAVITDGTAVLGLGNIGPEASIPVMEGKAVLFKSFAGINGVPIALNTTDTEEIIKTVKLLEPNYGGINLEDISAPRCFEIEERLKKETNIPVFHDDQHGTAIVTMAGLVNALRVVNKDIAKIKVVLNGAGAAGIAIVKLLYAYGVRNMVMCDSRGAIFEGRSYGMNPTKDVVAKWTNKDKIEGSLEEVVKDADVFIGVSVANALSQDMVKSMADNPIIFAMANPNPEIIPDDAKAAGARVVGTGRSDYPNQINNVLAFPGIFRGALEVEATHINEEMKKAAVEAIADLIDSSELNEDYCIPGPFDKRVAPSVARNVAKAAMESGVARIEVDPQDVYDKTMKLTDLQ
>NZ_CP029629.1|WP_000471571.1|1022377_1023235_+|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta
MFKDFFNRTKKKKYLTVQDSKNNDVPAGIMTKCPKCKKIMYTKELAENLNVCFNCDHHIALTAYKRIEAISDEGSFTEFDKGMTSANPLDFPSYLEKIEKDQQKTGLKEAVVTGTAQLDGMKFGVAVMDSRFRMGSMGSVIGEKICRIIDYCTENRLPFILFSASGGARMQEGIISLMQMGKTSVSLKRHSDAGLLYISYLTHPTTGGVSASFASVGDINLSEPKALIGFAGRRVIEQTINEKLPDDFQTAEFLLEHGQLDKVVHRNDMRQTLSEILKIHQEVTK
>NZ_CP029629.1|WP_000883648.1|1023234_1024179_+|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha
MLDFEKPLFEIRNKIESLKESQDKNDVDLQEEIDMLEASLERETKKIYTNLKPWDRVQIARLQERPTTLDYIPYIFDSFMELHGDRNFRDDPAMIGGIGFLNGRAVTVIGQQRGKDTKDNIYRNFGMAHPEGYRKALRLMKQAEKFNRPIFTFIDTKGAYPGKAAEERGQSESIATNLIEMASLKVPVIAIVIGEGGSGGALGIGIANKVLMLENSTYSVISPEGAAALLWKDSNLAKIAAETMKITAHDIKQLGIIDDVISEPLGGAHKDVEQQALAIKSAFVAQLDSLESLSRDEIANDRFEKFRNIGSYIE
>NZ_CP029629.1|WP_000717561.1|1024447_1025416_+|6-phosphofructokinase
MKKIAVLTSGGDSPGMNAAVRAVVRTAIYNEIEVYGVYHGYQGLLNDDIHKLELGSVGDTIQRGGTFLYSARCPEFKEQEVRKVAIENLRKRGIEGLVVIGGDGSYRGAQRISEECKEIQTIGIPGTIDNDINGTDFTIGFDTALNTIIGLVDKIRDTASSHARTFIIEAMGRDCGDLALWAGLSVGAETIVVPEVKTDIKEIADKIEQGIKRGKKHSIVLVAEGCMTAQDCQKELSQYINVDNRVSVLGHVQRGGSPTGADRVLASRLGGYAVDLLMQGETAKGVGIKNNKIVATSFDEIFDGKDHKFDYSLYELANKLSI
>NZ_CP029629.1|WP_110161672.1|1025437_1027195_+|pyruvate-kinase
MRKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAILLDTKGPEIRTHNMKDGIIELERGNEVIVSMNEVEGTPEKFSVTYENLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNLPGVRVSLPGITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFPKIENQEGIDNIAEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSLVNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVTPSEETARQCSIVWGVQPVVKKGRKSTDALLNNAVATAVETGRVSNGDLIIITAGVPTGETGTTNMMKIHLVGDEIANGQGIGRGSVVGTTLVAETVKDLEGKDLSDKVIVTNSIDETFVPYVEKALGLITEENGITSPSTIVGLEKGIPTVVGVEKAVKNISNNMLVTIDAAQGKIFEGYANVL
>NZ_CP029629.1|WP_000818525.1|1029520_1030882_-|amino-acid-permease
MAEKLQRELSNRHIQLIAIGGAIGTGLFLGAGQTIALTGPSILLTYIIIGFMLFMFMRGLGEIIIQNTEFKSFADVTNTYIGPFAGFVTGWTYWFCWIITGMAEVTAVAKYVSFWFPEIPNWISALFCVLLLMSFNLLSARLFGELEFWFSIIKIATIIGLIVVGFVMILFAFKTQFGHASFTNLYEHGIFAKGASGFFMSFQMALFSFVGIEMIGVTAGETKDPVKTIPKAINSVPIRILIFYVGALAVIMSIIPWQQVDPDNSPFVKLFALIGIPFAAGLINFVVLTAAASSCNSGIFSNSRMLFGLSSQQQAPPNFSKTNKYGVPHVAIFASSALLLVAALLNYIFPDATKVFTYVTTISTVLFLVVWGLIIIAYINYSRKNPDLHKNATYKLLGGKYMGYLIFVFFIFVFGLLFINVDTRRAIYFIPIWFILLAFMYLRYKRIAAKSNK
>NZ_CP029629.1|WP_000829167.1|1031229_1032351_+|citrate-synthase
MAELQRGLEGVIAAETKISSIIESQLTYAGYDIDDLAENAQFEEVIFLLWNYRLPNEEELAHLKGKLNQYMTLNPRVYTHFEEYVTDHVHPMTALRTSLSYIAHFDPDAENESDENRYERAMRIQAKVASLVTAFARVRQDKEPLKPNPDLSYAANFLYMLRGELPTDIEVEAFNKALILHADHELNASAFTARCAVSSLSDMYSGIVAAVGSLKGPLHGGANEQVMTMLSEIGSIENVDAYLDEKFANKDKVMGFGHRVYKDGDPRAKYLREMSRQITKDAGREELFEMSVKMEKRMAEEKGLIPNVDFYSASVYHCMEIPHDLFTPIFAVSRSAGWIAHILEQYKDNRIMRPRAKYIGETNRKYIPLEERK
>NZ_CP029629.1|WP_000123164.1|1032399_1033668_+|NADP-dependent-isocitrate-dehydrogenase
MTAEKITQGTEGLNVPNEPIIPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEWLPQETLDTIKEYLIAVKGPLTTPIGGGIRSLNVALRQELDLFTCLRPVRWFKGVPSPVKRPQDVDMVIFRENTEDIYAGIEFKEGTTEVKKVIDFLQNEMGATNIRFPETSGIGIKPVSKEGTERLVRAAIQYAIDNNRKSVTLVHKGNIMKFTEGSFKQWGYDLALSEFGDQVFTWQQYDEIVEKEGRDAANAAQEKAEKEGKIIIKDSIADIFLQQILTRPAEHDVVATMNLNGDYISDALAAQVGGIGIAPGANINYETGHAIFEATHGTAPKYAGLNKVNPSSVILSSVLMLEHLGWQEAADKITDSIEDTIASKVVTYDFARLMDGAEEVSTSAFADELIKNLK

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Crispr_ID: NZ_CP029629_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP029629_3

1733468-1733562

Orphan

Consensus_repeat	Method
CCTTACAACCTTTAGTTGTTAGGGGCTTTTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP029629_3

>merge|NZ_CP029629|3|1733468-1733562|CRISPRCasFinder
CCTTACAACCTTTAGTTGTTAGGGGCTTTTTTGCTTGCGCTCGGTGCATGTATCCCTCTTTTACCTTACAACTTTTAGTTGTTAGGGGCTTTTTT

>NZ_CP029629|3|3|1733468-1733562|CRISPRCasFinder
CCTTACAACCTTTAGTTGTTAGGGGCTTTTTT	GCTTGCGCTCGGTGCATGTATCCCTCTTTTA
CCTTACAACTTTTAGTTGTTAGGGGCTTTTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP029629.1\|WP_000064214.1\|1733323_1733458_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029629.1\|WP_110161687.1\|1727542_1729261_-\|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl\|CDD\|224006
NZ_CP029629.1\|WP_000009069.1\|1731876_1733172_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029629.1\|WP_001101924.1\|1737097_1738345_-\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|237507
NZ_CP029629.1\|WP_000514290.1\|1723702_1724365_-\|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|223643
NZ_CP029629.1\|WP_000381849.1\|1725513_1726875_-\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
NZ_CP029629.1\|WP_000709277.1\|1738366_1739845_-\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
NZ_CP029629.1\|WP_000273253.1\|1736024_1736831_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NZ_CP029629.1\|WP_000638456.1\|1724497_1725517_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|224213
NZ_CP029629.1\|WP_000238669.1\|1739859_1740426_-\|phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|223376
NZ_CP029629.1\|WP_000033477.1\|1734041_1734617_+\|ECF-transporter-S-component	unknown	unknown	gnl\|CDD\|227065
NZ_CP029629.1\|WP_070001857.1\|1741449_1742934_-\|amidophosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235984
NZ_CP029629.1\|WP_000030811.1\|1740428_1741457_-\|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl\|CDD\|235439
NZ_CP029629.1\|WP_001289618.1\|1727072_1727306_+\|glutaredoxin-like-protein-NrdH	unknown	unknown	gnl\|CDD\|239274
NZ_CP029629.1\|WP_000032740.1\|1742912_1745102_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	unknown	unknown	gnl\|CDD\|234921
NZ_CP029629.1\|WP_000505966.1\|1729683_1730226_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368297
NZ_CP029629.1\|WP_000437472.1\|1729263_1729530_-\|phosphocarrier-protein-HPr	unknown	unknown	gnl\|CDD\|237503
NZ_CP029629.1\|WP_000921973.1\|1734631_1736032_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213192
NZ_CP029629.1\|WP_000685070.1\|1730279_1731452_-\|class-I-SAM-dependent-rRNA-methyltransferase	unknown	unknown	gnl\|CDD\|224017
NZ_CP029629.1\|WP_000666806.1\|1745094_1745766_-\|phosphoribosylformylglycinamidine-synthase-I	unknown	unknown	gnl\|CDD\|235140

Protein	Function_ID	Function_description	E-value
NZ_CP029629.1\|WP_110161687.1\|1727542_1729261_-\|phosphoenolpyruvate--protein-phosphotransferase	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
NZ_CP029629.1\|WP_000381849.1\|1725513_1726875_-\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	2.48829e-165
NZ_CP029629.1\|WP_000238669.1\|1739859_1740426_-\|phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|223376	COG0299, PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism].	1.14152e-91
NZ_CP029629.1\|WP_001101924.1\|1737097_1738345_-\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|237507	PRK13790, PRK13790, phosphoribosylamine--glycine ligase; Provisional.	0
NZ_CP029629.1\|WP_000514290.1\|1723702_1724365_-\|TrkA-family-potassium-uptake-protein	gnl\|CDD\|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	4.35421e-66
NZ_CP029629.1\|WP_000709277.1\|1738366_1739845_-\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NZ_CP029629.1\|WP_000273253.1\|1736024_1736831_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	7.39205e-29
NZ_CP029629.1\|WP_000638456.1\|1724497_1725517_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|224213	COG1294, AppB, Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion].	6.42118e-76
NZ_CP029629.1\|WP_070001857.1\|1741449_1742934_-\|amidophosphoribosyltransferase	gnl\|CDD\|235984	PRK07272, PRK07272, amidophosphoribosyltransferase; Provisional.	0
NZ_CP029629.1\|WP_000033477.1\|1734041_1734617_+\|ECF-transporter-S-component	gnl\|CDD\|227065	COG4721, COG4721, ABC-type cobalt transport system, predicted permease component [Inorganic ion transport and metabolism].	4.34592e-70
NZ_CP029629.1\|WP_000666806.1\|1745094_1745766_-\|phosphoribosylformylglycinamidine-synthase-I	gnl\|CDD\|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	7.86572e-140
NZ_CP029629.1\|WP_000030811.1\|1740428_1741457_-\|phosphoribosylformylglycinamidine-cyclo-ligase	gnl\|CDD\|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
NZ_CP029629.1\|WP_001289618.1\|1727072_1727306_+\|glutaredoxin-like-protein-NrdH	gnl\|CDD\|239274	cd02976, NrdH, NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase activity that is dependent on TRX reductase, not glutathione (GSH). It is part of the NrdHIEF operon, where NrdEF codes for class Ib ribonucleotide reductase (RNR-Ib), an efficient enzyme at low oxygen levels. Under these conditions when GSH is mostly conjugated to spermidine, NrdH can still function and act as a hydrogen donor for RNR-Ib. It has been suggested that the NrdHEF system may be the oldest RNR reducing system, capable of functioning in a microaerophilic environment, where GSH was not yet available. NrdH from Corynebacterium ammoniagenes can form domain-swapped dimers, although it is unknown if this happens in vivo. Domain-swapped dimerization, which results in the blocking of the TRX reductase binding site, could be a mechanism for regulating the oxidation state of the protein.	1.21197e-16
NZ_CP029629.1\|WP_000032740.1\|1742912_1745102_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	gnl\|CDD\|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0
NZ_CP029629.1\|WP_000505966.1\|1729683_1730226_-\|hypothetical-protein	gnl\|CDD\|368297	pfam05128, DUF697, Domain of unknown function (DUF697). Family of bacterial hypothetical proteins that is sometimes associated with GTPase domains.	0.00844137
NZ_CP029629.1\|WP_000437472.1\|1729263_1729530_-\|phosphocarrier-protein-HPr	gnl\|CDD\|237503	PRK13780, PRK13780, phosphocarrier protein HPr; Provisional.	2.44795e-51
NZ_CP029629.1\|WP_000921973.1\|1734631_1736032_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	1.87437e-64
NZ_CP029629.1\|WP_000685070.1\|1730279_1731452_-\|class-I-SAM-dependent-rRNA-methyltransferase	gnl\|CDD\|224017	COG1092, COG1092, Predicted SAM-dependent methyltransferases [General function prediction only].	4.46718e-146

>NZ_CP029629.1|WP_000064214.1|1733323_1733458_+|hypothetical-protein
MSNENQNKKAAEKAKEVEEKLKDKKEEKTEDINQTKQDIQDTLN
>NZ_CP029629.1|WP_000009069.1|1731876_1733172_-|hypothetical-protein
MSFLRKHAEIIFSYLIGIVSLFTGLIILINLPLIKQLNGGKKVDTHVHNVWEFLNAFFSEIIKVMSRFIGNFPIVSAIVIIIFGILVMLIGHTLLRTIKYDYDISIFFLVIGIMYFIITLILMTQVYGFFAVIFIIPFTIHIGYIVYKDELNQENVKNHFMWIIVSYGISYLITQIALYGRIDANEIESIDILSVNAFFIIMWLLGQMAIWNFLFLRRALPLTKQELGEEEPELSRTSKGNVTNQTKIHLKQLQDKTTEYARKTRRSVDLDKIRAKRDKFKKKVNDIIDIQEDDIPDWMRKPKWVKPMYVELFCGVVIFLFTFLEFNNRNALFVSGDWKLSQTQYVIEWVTLLILLFIIIAYIATTLTFHLKGKFYYLQLFMGSILFFKLLTEFINIMIHGLLLSVFITPTLLLMLLAIIISYSLQLRERP
>NZ_CP029629.1|WP_000685070.1|1730279_1731452_-|class-I-SAM-dependent-rRNA-methyltransferase
MKIATLNKGKETKYFNGYPLIEEEDIYSQDHLKEGDIFQIVTDKSQYVATAYVGRQHKGLGWVLTYDKAQEINTAFFVKLFNTALAERDYYFNIDGTNTFRLFNAEGDGVGGLTIDNYDGHLLIQWYSKGIYKFKYAILEAVRKVFDYKSIYEKVRFKDSEYSGGFVEGDAPEFPIVIEENFTFYNVDLEDGLMTGIFLDQKEVRKKLRGQYAKERHVLNLFSYTGAFSVIAASEASSTTSVDLANRSRSLTEENFGLNAIDPKSQYIYVMDTFDFYKYAARHGHSYDTIVIDPPSFARNKKRTFSVQKDYDKLINGALNILSSEGTLLLCTNASVYPLKQFKNTIKKTLEESGVDYELTEVMGLPKDFKTHPHYKPSKYLKAVFVNIRH
>NZ_CP029629.1|WP_000505966.1|1729683_1730226_-|hypothetical-protein
MGFKNNLTSNLTNKIGNSVFKIENVDGKGAMPTTIQELRERRQRAEAIVKRKSLMSSTMSVVPIPGLDFGVDLKLMKDIIEDVNKIYGLDHKQVNSLGDDVKERIMSAAAIQGSQFIGKRISSAFLKIVIRDVAKRTAAKQTKWFPVVGQAVSASISYYFMNKIGKDHIQKCENVIKNVM
>NZ_CP029629.1|WP_000437472.1|1729263_1729530_-|phosphocarrier-protein-HPr
MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK
>NZ_CP029629.1|WP_110161687.1|1727542_1729261_-|phosphoenolpyruvate--protein-phosphotransferase
MSKLIKGIAASDGVAIAKAYLLVEPDLTFDKNEKVTDVEGEVAKFNSAIEASKVELTKIRNNAEVQLGADKAAIFDAHLLVLDDPELIQPIQYKIKNENANAATALTDVTTQFVTIFESMDNEYMKERAADIRDVSKRVLSHILGVELPNPSMIDESVVIVGNDLTPSDTVQLNKEFVQGFATNIGGRTSHSAIMSRSLEIPAIVGTKSITQEVKQGDMIIVDGLNGDVIVNPTEDELIAYQDKRERYFADKKELQKLRDADTVTVDGVHAELAANIGTPNDLPGVIENGAQGIGLYRTEFLYMGRDQMPTEGEQFEAYKEVLEAMDGKRVVVRTLDIGGDKELSYLNLPEEMNPFLGYRAIRLCLAQQDIFRPQLRALLRASVYGKLNIMFPMVATINEFREAKAILLEEKENLKNEGHDISDDIELGIMVEIPATAALADVFAKEVDFFSIGTNDLIQYTLAADRMSERVSYLYQPYNPSILRLVKQVIEASHKEGKWTGMCGEMAGDETAIPLLLGLGLDEFSMSATSILKARRQINGLSKNEMTELANRAVDCATQEEVIELVNNYVK
>NZ_CP029629.1|WP_001289618.1|1727072_1727306_+|glutaredoxin-like-protein-NrdH
MSEIIVYTQNDCPPCTFVKNYLNEHQIDFEERNINNQQYRNEMIDFDAFSTPFILLNGNPMYHVDLDEINKVLNIQD
>NZ_CP029629.1|WP_000381849.1|1725513_1726875_-|cytochrome-ubiquinol-oxidase-subunit-I
MDTVEISRFLTAMTLAVHIIFATIGVGMPLMFAIAEFLGIRKNDLQYIAMAKRWAKAYTITVAVGVVTGTIIGLQLSLIWPTFMEMGGHVIALPLFMETFAFFFEAIFLSIYLYTWDRFKNKWTHFLISIPVIIGGSFSAFFITSVNSFMNTPAGFELKNGKMVNVQPIEAMFNPSFIVRSFHVITTAGMTMAFVIASIAAFKLLRNRQPKDTVYHKKALKMSMIVGFFSTLLSMLAGDLSAKFLHKFQPEKLAAYEWHFDTSSHAKLLLFGVLDEKTQQVKGAIELPGLLSFLADNSVKTKVQGLNDFPKSLHPPMIVHYFFDLMVTMGILCFVISGVYVLTLMFKKLRKFSTHKWMLYGILLTGPASMLAIEFGWFLTEMGRQPWIVRGYMRVAEAATQAGGITFVTILFGILYIILMYTCAYVLIRMFKNKPAYEDVNRLAKKQGGEIEK
>NZ_CP029629.1|WP_000638456.1|1724497_1725517_-|cytochrome-d-ubiquinol-oxidase-subunit-II
MIYAFIGITVLWLFLFCYIIIASIDFGAGFFALHSKLTGDEKKINHLISRYLNPVWEVTNVFFVFFFVGFVGFFPESIKYLGTVLLIPGSIALIMISLRNSFYAFENYGQDTKLAWMIMYGVSGLLIPASLSTALTITEGGYINVRNNVIDLDWVQLLLSPFAWSVVFLAIISVLYISSGFLTYYAKKANDEPAYNLTRQWHIFLGPPMIIICLFVFLSLRIQNSEHFYSAVFDYWWMFGISFLFFALASLLTFFKKKHGLAFVFVILQMMFAFFGYGISKLPYLLYPFVKITDAYVNPEMGWTLVIVFILGLLLLLPSLILLLRLFVFDKEYVEGKKS
>NZ_CP029629.1|WP_000514290.1|1723702_1724365_-|TrkA-family-potassium-uptake-protein
MGKEYVVIGLGRFGGSIVRELNALDMDVMAIDHDENRVNEYSDIATHAVVADTTDEAVMKSLGIRNFDHVIVAIGENIQSSTLTTLILKELGVKKVTAKAQNDYHAKILNKIGADTVVHPERDMGRRIAHNVASASVLDYLELADEHSIVELKATEKMAGQSIIDLDIRAQYGINIIAIKRGKEFIISPNPNINLEIGDILIMIGHDNDLNRFEKNIATR
>NZ_CP029629.1|WP_000033477.1|1734041_1734617_+|ECF-transporter-S-component
MSKGLKLSEILVTVLISVVFAVIYNLWWFVYNGVQATGLHLEQLTNGVWFMAAIVCYLIIPKPGIALLAEFAAGAGETIIMGRFDIPTIVYAFIQGLACELVFAIFKYQSRSVMVAMLAGFCTAIAAFPIDYFYGYLNEVAGWNLTLFIVFRLISGAVVAGVLSYLLVKALDKTGVTKLFRPAAKEDYDNL
>NZ_CP029629.1|WP_000921973.1|1734631_1736032_+|ABC-transporter-ATP-binding-protein
MLKVSDLRLKYPSGQRKIFDHLNITIQDKEKVLLLGPSGCGKSTLLNVLSGIVPNLIELPMKYDELIVDPLSGVIFQDPDSQFCMPKVYEELAFVLENRQVPREDMDALIINALNMVNLNVTPETYIKDLSGGMKQKLAIVETILQQSKTLFLDEPTAMLDVQATEDLWTKLIELWEDQTVVIVEHKVKHIWNHVDRVILMDYNGNIIADECPEIILQKYVHLLSEYGVWHPRAWEFAPSRVDFPTTNSHLLQFKNGRIIRGKSTLLSFSDLEIGLGEWITITGANGSGKTTLLESIMQLIKYQGDVYFENQRLTKIKHAAKHMYLVYQNPELQFITNSVYDEINIHFNHLSKDQSDDETIQLLKLLDLQNVKDQHPYELSIGQKRRLSVATALSSKADIIFLDEPTFGLDSHNTFQLIKLFQKRINLGQSIVMVTHDDEIIERYPSRRLKISDGALLDCDGDTNV
>NZ_CP029629.1|WP_000273253.1|1736024_1736831_+|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MYEQWKVRQSFVDDVNIITKLFLGIILFFFIIFVHNFDFMLYITILMLVFLLMFNGTQFKITAIFITISIGFALLSSLFMILYGNGSHTILKFGFIHITTESLVRGLHVSLRTIAISFFGILIALTSQVVMIFYSLMQHLKVKSKVAYAFMAAIRMIPLMISSLIQLRRSLKMRYQMIDAANYRGLKRFKHLIIPLLSQNIRKAHQLSVAMESKGFRDGPRTYYYNVPFSYKDIIFIIVLIAIITMAYYCSITLPITGIDDVRLGRVG
>NZ_CP029629.1|WP_001101924.1|1737097_1738345_-|phosphoribosylamine--glycine-ligase
MNVLVIGAGGREHALAYKLNQSNLVKQVFVIPGNEAMTPIAEVHTEISESNHQGILDFAKQQNVDWVVIGPEQPLIDGLADILRANGFKVFGPNKQAAQIEGSKLFAKKIMKKYNIPTADYKEVERKKDALTYIENCELPVVVKKDGLAAGKGVIIADTIEAARSAIEIMYGDEEEGTVVFETFLEGEEFSLMTFVNGDLAVPFDCIAQDHKRAFDHDEGPNTGGMGAYCPVPHISDDVLKLTNETIAQPIAKAMLNEGYQFFGVLYIGAILTKDGPKVIEFNARFGDPEAQVLLSRMESDLMQHIIDLDEGKRTEFKWKNESIVGVMLASKGYPDAYEKGHKVSGFDLNENYFVSGLKKQGDTFVTSGGRVILAIGKGDNVQDAQRDAYEKVSQIQSDHLFYRHDIANKALQLK
>NZ_CP029629.1|WP_000709277.1|1738366_1739845_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MKKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYHEVLTRLRNDSLDESYRQSLMIKVFEHTAEYDEAIVRFFKGDKETLRYGENPQQSAYFVRTSNAKHTIAGAKQLHGKQLSYNNIKDADATLALVKKFDTPAAVAVKHMNPCGVGIGDTIEQAFQHAYEADSQSIFGGIVALNRAVTPELAEQLHSIFLEVIIAPKFTDEALDILKQKKNVRLLEIDMTIDSNEEEFVSVSGGYLVQDKDNYVVPKEEMKVVTEVAPTDEQWEAMLLGWKVVPSVKSNAIILSNNKQTVGIGAGQMNRVGAAKIALERAIEINDHVALVSDGFFPMGDTVELAAQHGIKAIIQPGGSIKDQDSIDMANKHGIAMVVTGTRHFKH
>NZ_CP029629.1|WP_000238669.1|1739859_1740426_-|phosphoribosylglycinamide-formyltransferase
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEPKQFDSKAAYEQHLVTLLNKDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDCGMDTGEIIEQRQCDIRPDDSKEQLEEKVKKLEYELYPSVIAKIVK
>NZ_CP029629.1|WP_000030811.1|1740428_1741457_-|phosphoribosylformylglycinamidine-cyclo-ligase
MSKAYEQSGVNIHAGYEAVERMSSHVKRTMRKEVIGGLGGFGATFDLSQLNMTAPVLVSGTDGVGTKLKLAIDYGKHDSIGIDAVAMCVNDILTTGAEPLYFLDYIATNKVVPEVIEQIVKGISDACVETNTALIGGETAEMGEMYHEGEYDVAGFAVGAVEKDDYVDGSEVKEGQVVIGLASSGIHSNGYSLVRKLINESGIDLASNFDNRPFIDVFLEPTKLYVKPVLALKKEVSIKAMNHITGGGFYENIPRALPAGYAARIDTTSFPTPKIFDWLQQQGNIDTNEMYNIFNMGIGYTVIVDEKDASRALKILAEQNVEAYQIGHIVKNESTAIELLGV
>NZ_CP029629.1|WP_070001857.1|1741449_1742934_-|amidophosphoribosyltransferase
MFNYSGLNEECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIVVSDQNELKGERGLGLLTEAINDDQMERLKGYQHAIGHVRYATSGNKGIENIQPFLYHFYDMSVGICHNGNLINAKSLRQNLEKQGAIFHSSSDTEVIMHLIRRSKAPTFEEALKESLRKVKGGFTFAILTKDALYGAVDPNAIRPLVVGKMKDGTYILASETCAIDVLGAEFVQDIHAGEYVVINDKGITVKSYTHHTTTAISAMEYIYFARPDSTIAGKNVHAVRKASGKKLAQESPVNADMVIGVPNSSLSAASGYAEEIGLPYEMGLVKNQYVARTFIQPTQELREQGVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRRIVKMLKDSGANKVHVRIASPEFMFPSFYGIDVSTTAELISASKSPEEIKDYIGADSLAYLSVDGLIESIGLDYDAPYSGLCVEIFTGDYPAGLYDYEANYKAHLSHRQKQYISKNKHFFDSEGNLNV
>NZ_CP029629.1|WP_000032740.1|1742912_1745102_-|phosphoribosylformylglycinamidine-synthase-subunit-PurL
MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGEHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGYGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQERMLLVVEKGNEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKDYNTSKNDYTHIDVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAIAQCLTTQD
>NZ_CP029629.1|WP_000666806.1|1745094_1745766_-|phosphoribosylformylglycinamidine-synthase-I
MKFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDYRETSLSGFDGVLIPGGFSFGDYLRSGAMASVAPIISEVKRLATEGKPVLGVCNGFQILTEIGLLPGALLHNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDEIYQQLKANNQIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERALETLLGTDSGVKLFEAMVKSWREQHV

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Crispr_ID: NZ_CP029629_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP029629_4

1924028-1924109

Orphan

Consensus_repeat	Method
TTCTACAGGCAATGCAAGTTGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP029629_4

>merge|NZ_CP029629|4|1924028-1924109|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGATGGGCCCCAACAAAGAGAAATTGGATTCTCAATTTCTACAGACAATGCAAGTTGGGG

>NZ_CP029629|4|4|1924028-1924109|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGG	ATGGGCCCCAACAAAGAGAAATTGGATTCTCAAT
TTCTACAGACAATGCAAGTTGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP029629.1\|WP_001140697.1\|1930423_1931005_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NZ_CP029629.1\|WP_000752919.1\|1919277_1919472_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_CP029629.1\|WP_001183858.1\|1918192_1919044_+\|DUF368-domain-containing-protein	unknown	unknown	gnl\|CDD\|224946
NZ_CP029629.1\|WP_000569887.1\|1929084_1929579_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
NZ_CP029629.1\|WP_000422908.1\|1926777_1927317_-\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
NZ_CP029629.1\|WP_000168845.1\|1917103_1917865_-\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NZ_CP029629.1\|WP_070001830.1\|1925807_1926164_-\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
NZ_CP029629.1\|WP_000290490.1\|1925269_1925650_-\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_CP029629.1\|WP_000974460.1\|1928263_1928686_+\|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
NZ_CP029629.1\|WP_000932212.1\|1924212_1925091_-\|DUF1963-domain-containing-protein	unknown	unknown	gnl\|CDD\|226395
NZ_CP029629.1\|WP_000150013.1\|1927399_1928116_-\|type-I-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
NZ_CP029629.1\|WP_000255553.1\|1929733_1930351_+\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
NZ_CP029629.1\|WP_000205580.1\|1915697_1917005_-\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NZ_CP029629.1\|WP_001006453.1\|1914341_1915592_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NZ_CP029629.1\|WP_001190695.1\|1926307_1926628_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP029629.1\|WP_000520233.1\|1920664_1921360_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NZ_CP029629.1\|WP_000571218.1\|1921352_1922378_-\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NZ_CP029629.1\|WP_001065801.1\|1922627_1922924_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP029629.1\|WP_001018962.1\|1922916_1923303_-\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
NZ_CP029629.1\|WP_000732326.1\|1919825_1920647_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381

Protein	Function_ID	Function_description	E-value
NZ_CP029629.1\|WP_001140697.1\|1930423_1931005_-\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	2.29633e-48
NZ_CP029629.1\|WP_000752919.1\|1919277_1919472_-\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	7.31744e-07
NZ_CP029629.1\|WP_001183858.1\|1918192_1919044_+\|DUF368-domain-containing-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	4.58436e-76
NZ_CP029629.1\|WP_000569887.1\|1929084_1929579_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	3.90374e-46
NZ_CP029629.1\|WP_000422908.1\|1926777_1927317_-\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	2.10032e-49
NZ_CP029629.1\|WP_000168845.1\|1917103_1917865_-\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.29081e-150
NZ_CP029629.1\|WP_070001830.1\|1925807_1926164_-\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	6.79692e-56
NZ_CP029629.1\|WP_000290490.1\|1925269_1925650_-\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	1.28962e-69
NZ_CP029629.1\|WP_000974460.1\|1928263_1928686_+\|organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	5.58225e-61
NZ_CP029629.1\|WP_000932212.1\|1924212_1925091_-\|DUF1963-domain-containing-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	1.72543e-74
NZ_CP029629.1\|WP_000150013.1\|1927399_1928116_-\|type-I-3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	5.95463e-148
NZ_CP029629.1\|WP_000255553.1\|1929733_1930351_+\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	1.40612e-61
NZ_CP029629.1\|WP_000205580.1\|1915697_1917005_-\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	6.84378e-136
NZ_CP029629.1\|WP_001006453.1\|1914341_1915592_-\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_CP029629.1\|WP_001190695.1\|1926307_1926628_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.70086e-24
NZ_CP029629.1\|WP_000520233.1\|1920664_1921360_-\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	9.67625e-100
NZ_CP029629.1\|WP_000571218.1\|1921352_1922378_-\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	3.37873e-170
NZ_CP029629.1\|WP_001065801.1\|1922627_1922924_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
NZ_CP029629.1\|WP_001018962.1\|1922916_1923303_-\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
NZ_CP029629.1\|WP_000732326.1\|1919825_1920647_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	2.15951e-112

>NZ_CP029629.1|WP_001018962.1|1922916_1923303_-|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>NZ_CP029629.1|WP_001065801.1|1922627_1922924_-|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>NZ_CP029629.1|WP_000571218.1|1921352_1922378_-|methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEQGPVTQVFENPQHTVTKRFVKDDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>NZ_CP029629.1|WP_000520233.1|1920664_1921360_-|ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>NZ_CP029629.1|WP_000732326.1|1919825_1920647_-|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>NZ_CP029629.1|WP_000752919.1|1919277_1919472_-|CsbD-family-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKSNKGE
>NZ_CP029629.1|WP_001183858.1|1918192_1919044_+|DUF368-domain-containing-protein
MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTSLIIKYFIAGMCASSAMLLPGISGSFMLLVFGVYGTVMLAISEVVKLNFAGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>NZ_CP029629.1|WP_000168845.1|1917103_1917865_-|Fe-S-cluster-assembly-ATPase-SufC
MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>NZ_CP029629.1|WP_000205580.1|1915697_1917005_-|Fe-S-cluster-assembly-protein-SufD
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKYFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDKNASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLIGDRSTSSLKSVVVGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
>NZ_CP029629.1|WP_001006453.1|1914341_1915592_-|cysteine-desulfurase
MNEVAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDIDQLINALKQTKEFFSYEF
>NZ_CP029629.1|WP_000932212.1|1924212_1925091_-|DUF1963-domain-containing-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMKEETLNQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLDNLPEQQELFPVKEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQEHLKSLDADNEDIPFSGAFSIKFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>NZ_CP029629.1|WP_000290490.1|1925269_1925650_-|glycine-cleavage-system-protein-GcvH
MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQIEALLTAEKYSKMIGE
>NZ_CP029629.1|WP_070001830.1|1925807_1926164_-|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKIIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>NZ_CP029629.1|WP_001190695.1|1926307_1926628_+|thioredoxin-family-protein
MQSIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>NZ_CP029629.1|WP_000422908.1|1926777_1927317_-|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEEDMPKAPRKNRNLITLY
>NZ_CP029629.1|WP_000150013.1|1927399_1928116_-|type-I-3-dehydroquinate-dehydratase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFTNDLYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGEPQAPGQIDVTDLKAQVTLY
>NZ_CP029629.1|WP_000974460.1|1928263_1928686_+|organic-hydroperoxide-resistance-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>NZ_CP029629.1|WP_000569887.1|1929084_1929579_+|GNAT-family-N-acetyltransferase
MIEIKTLTNNNFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>NZ_CP029629.1|WP_000255553.1|1929733_1930351_+|amino-acid-transporter
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIITAGLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGEAQIMSPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGKMVGSIDKTGKLLTIINKISSIIIIIVALMILQKLIQLIF
>NZ_CP029629.1|WP_001140697.1|1930423_1931005_-|histidine-phosphatase-family-protein
MAKTLYLMRHGQTLFNFKGLIQGFGDSPLTELGIAQAQKARSYYETKGINFDLYASSTQERASDTLENVAPNQSYQRFKGLKEWHFGLFEGESVYLFDNLYKPEDLFGDRIVPFKGEARQQVEERIVKTLHDIMSQTKNNALVVSHGTIMGVFLRYCLKLDEALKHNIGNCNILKFEYDNGTFKFVELIDPNL

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Crispr_ID: NZ_CP029629_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP029629_5

1967137-1967279

Unclear

Consensus_repeat	Method
ATGCAAGTTGGCGGGGCCCCAACACAGAGAATTACGAAAAG	PILER-CR
AATTTCTACAGACAATGCAAGTTGG	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP029629_5

>merge|NZ_CP029629|5|1967137-1967279|PILER-CR,CRISPRCasFinder
GGGGCCCCAACACAGAGAAATTGGATTTCCAATTTCTACAGACAATGCAAGTTGGGGTGTGGGCCCCAACACAGAGAATTTCGAAAAGAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACACAGAAGCTTACGAAAAG

>NZ_CP029629|5|1|1967137-1967279|PILER-CR
GGGGCCCCAACACAGAGAAATTGGATTTCCAATTTCTACAGACAATGCAAGT	TGGGGTGTGGGCCCCAACACAGAGA
ATTTCGAAAAGAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACACAG	AAGCTTACGA
AAAG

>NZ_CP029629|5|5|1967167-1967249|CRISPRCasFinder
AATTTCTACAGACAATGCAAGTTGG	GGTGTGGGCCCCAACACAGAGAATTTCGAAAAG
AATTTCTACAGACAATGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP029629.1\|WP_000749383.1\|1979170_1980010_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP029629.1\|WP_001248939.1\|1964997_1965993_-\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NZ_CP029629.1\|WP_000070831.1\|1960305_1960935_-\|DUF4887-domain-containing-protein	unknown	unknown	gnl\|CDD\|234750
NZ_CP029629.1\|WP_070001826.1\|1965989_1966901_-\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|224574
NZ_CP029629.1\|WP_070001825.1\|1973005_1975852_-\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_CP029629.1\|WP_000654030.1\|1958588_1959602_-\|sugar-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225263
NZ_CP029629.1\|WP_001224793.1\|1970115_1970601_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_CP029629.1\|WP_000638419.1\|1978113_1978350_-\|CsbA-family-protein	unknown	unknown	gnl\|CDD\|227234
NZ_CP029629.1\|WP_000057552.1\|1968668_1970108_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NZ_CP029629.1\|WP_110161692.1\|1957525_1958536_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|273675
NZ_CP029629.1\|WP_000958224.1\|1971453_1972386_-\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
NZ_CP029629.1\|WP_000538141.1\|1978346_1978997_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|378993
NZ_CP029629.1\|WP_001260101.1\|1955313_1956075_-\|triose-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
NZ_CP029629.1\|WP_000229236.1\|1975859_1977845_-\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
NZ_CP029629.1\|WP_000816304.1\|1961637_1962540_+\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|224015
NZ_CP029629.1\|WP_000513312.1\|1970608_1971448_-\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
NZ_CP029629.1\|WP_000134963.1\|1967666_1968602_-\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NZ_CP029629.1\|WP_000006551.1\|1963942_1964887_-\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NZ_CP029629.1\|WP_001074757.1\|1956196_1957387_-\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
NZ_CP029629.1\|WP_001049165.1\|1962782_1963370_-\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955

Protein	Function_ID	Function_description	E-value
NZ_CP029629.1\|WP_000749383.1\|1979170_1980010_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.97111e-42
NZ_CP029629.1\|WP_001248939.1\|1964997_1965993_-\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
NZ_CP029629.1\|WP_000070831.1\|1960305_1960935_-\|DUF4887-domain-containing-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	5.80381e-05
NZ_CP029629.1\|WP_070001826.1\|1965989_1966901_-\|RNase-adapter-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	1.52033e-168
NZ_CP029629.1\|WP_070001825.1\|1973005_1975852_-\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_CP029629.1\|WP_000654030.1\|1958588_1959602_-\|sugar-binding-transcriptional-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	1.39665e-92
NZ_CP029629.1\|WP_001224793.1\|1970115_1970601_-\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
NZ_CP029629.1\|WP_000638419.1\|1978113_1978350_-\|CsbA-family-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
NZ_CP029629.1\|WP_000057552.1\|1968668_1970108_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	2.98898e-05
NZ_CP029629.1\|WP_110161692.1\|1957525_1958536_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	0
NZ_CP029629.1\|WP_000958224.1\|1971453_1972386_-\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
NZ_CP029629.1\|WP_000538141.1\|1978346_1978997_-\|HD-domain-containing-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
NZ_CP029629.1\|WP_001260101.1\|1955313_1956075_-\|triose-phosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	2.48635e-146
NZ_CP029629.1\|WP_000229236.1\|1975859_1977845_-\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP029629.1\|WP_000816304.1\|1961637_1962540_+\|TIGR01777-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	6.73087e-155
NZ_CP029629.1\|WP_000513312.1\|1970608_1971448_-\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	4.82832e-120
NZ_CP029629.1\|WP_000134963.1\|1967666_1968602_-\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
NZ_CP029629.1\|WP_000006551.1\|1963942_1964887_-\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
NZ_CP029629.1\|WP_001074757.1\|1956196_1957387_-\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NZ_CP029629.1\|WP_001049165.1\|1962782_1963370_-\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148

>NZ_CP029629.1|WP_070001826.1|1965989_1966901_-|RNase-adapter-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLYKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>NZ_CP029629.1|WP_001248939.1|1964997_1965993_-|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>NZ_CP029629.1|WP_000006551.1|1963942_1964887_-|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>NZ_CP029629.1|WP_001049165.1|1962782_1963370_-|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>NZ_CP029629.1|WP_000816304.1|1961637_1962540_+|TIGR01777-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKVLFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGMILSNEGGALQTMKLPYKYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE
>NZ_CP029629.1|WP_000070831.1|1960305_1960935_-|DUF4887-domain-containing-protein
MSNQNYDYNKNEDGSKKKMSTTAKVVSIATVLLLLGGLVFAIFAYVDHSNKAKERMLNEQKQEQKEKRQKENAEKERKKKQQEEKEQNELDSQANQYQQLPQQNQYQYVPPQQQAPTKQRPAKEENDDKASKDESKDKDDNASQDKSDDNQKKTDDNKQPAQPKPQPQQPTPKPNNNQQNNQSNQQAKPQAPQQNSQSTTNKQNNANDK
>NZ_CP029629.1|WP_000654030.1|1958588_1959602_-|sugar-binding-transcriptional-regulator
MKDLLQAQQKLIPDLIDKMYKRFSILTTISKNQPVGRRSLSEHMDMTERVLRSETDMLKKQDLIKVKPTGMEITAEGEQLISQLKGYFDIYADDNRLSEGIKNKFQIKEVHVVPGDADNSQSVKTELGRQAGQLLEGILQEDAIVAVTGGSTMACVSEAIHLLPYNVFFVPARGGLGENVVFQANTIAASMAQQAGGYYTTMYVPDNVSETTYNTLLLEPSVINTLDKIKQANVILHGIGDALKMAHRRQSPEKVIEQLQHHQAVGEAFGYYFDTQGQIVHKVKTIGLQLEDLESKDFIFAVAGGKSKGEAIKAYLTIAPKNTVLITDEAAAKIILE
>NZ_CP029629.1|WP_110161692.1|1957525_1958536_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVIECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK
>NZ_CP029629.1|WP_001074757.1|1956196_1957387_-|phosphoglycerate-kinase
MAKKIVSDLNLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
>NZ_CP029629.1|WP_001260101.1|1955313_1956075_-|triose-phosphate-isomerase
MRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTVVKEGKAQGLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIFKHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSENQLKSVVIAYEPIWAIGTGKSSTSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLKVEDFVQLLEGAK
>NZ_CP029629.1|WP_000134963.1|1967666_1968602_-|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>NZ_CP029629.1|WP_000057552.1|1968668_1970108_-|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPVDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>NZ_CP029629.1|WP_001224793.1|1970115_1970601_-|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>NZ_CP029629.1|WP_000513312.1|1970608_1971448_-|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYVENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEKLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>NZ_CP029629.1|WP_000958224.1|1971453_1972386_-|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>NZ_CP029629.1|WP_070001825.1|1973005_1975852_-|excinuclease-ABC-subunit-UvrA
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSSGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>NZ_CP029629.1|WP_000229236.1|1975859_1977845_-|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIEEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQIRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>NZ_CP029629.1|WP_000638419.1|1978113_1978350_-|CsbA-family-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>NZ_CP029629.1|WP_000538141.1|1978346_1978997_-|HD-domain-containing-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>NZ_CP029629.1|WP_000749383.1|1979170_1980010_-|CHAP-domain-containing-protein
MKKSLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKTPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH

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Crispr_ID: NZ_CP029629_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP029629_6

2066560-2066658

Orphan

Consensus_repeat	Method
CCCCTTTTAATTTATTAATTAGGGGCTCTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP029629_6

>merge|NZ_CP029629|6|2066560-2066658|CRISPRCasFinder
CCCCTTTTAATTTATTAATTAGGGGCTCTTATGCAGTTGGTGCGTTAGCATCCAACTGTATTCCTTTGTCCCCTTTTAATTTATTAATTAGGGGCTCTT

>NZ_CP029629|6|6|2066560-2066658|CRISPRCasFinder
CCCCTTTTAATTTATTAATTAGGGGCTCTT	ATGCAGTTGGTGCGTTAGCATCCAACTGTATTCCTTTGT
CCCCTTTTAATTTATTAATTAGGGGCTCTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP029629.1\|WP_000865624.1\|2067724_2068369_-\|DUF402-domain-containing-protein	unknown	unknown	gnl\|CDD\|225188
NZ_CP029629.1\|WP_000820892.1\|2061301_2061868_+\|TIGR00730-family-Rossman-fold-protein	unknown	unknown	gnl\|CDD\|224527
NZ_CP029629.1\|WP_000833486.1\|2068721_2069195_-\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|226072
NZ_CP029629.1\|WP_000367063.1\|2065321_2066542_-\|sugar-efflux-transporter	unknown	unknown	gnl\|CDD\|341024
NZ_CP029629.1\|WP_000731641.1\|2074457_2075255_+\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP029629.1\|WP_000687412.1\|2066742_2067609_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP029629.1\|WP_001789973.1\|2068513_2068630_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029629.1\|WP_000152582.1\|2064836_2065325_-\|DUF456-domain-containing-protein	unknown	unknown	gnl\|CDD\|225395
NZ_CP029629.1\|WP_001090985.1\|2070100_2070460_-\|HTH-type-transcriptional-regulator-SarX	unknown	unknown	gnl\|CDD\|130944
NZ_CP029629.1\|WP_069993378.1\|2062573_2062885_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029629.1\|WP_000842860.1\|2064048_2064738_+\|DUF1129-family-protein	unknown	unknown	unknown
NZ_CP029629.1\|WP_000733433.1\|2063022_2063412_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029629.1\|WP_000532966.1\|2069194_2069911_-\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|237084
NZ_CP029629.1\|WP_000148828.1\|2060841_2061300_+\|YaiI/YqxD-family-protein	unknown	unknown	gnl\|CDD\|178882
NZ_CP029629.1\|WP_000638621.1\|2061963_2062506_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
NZ_CP029629.1\|WP_001129752.1\|2070605_2072756_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
NZ_CP029629.1\|WP_000081602.1\|2073452_2074097_-\|Bax-inhibitor-1-family-protein	unknown	unknown	gnl\|CDD\|223742
NZ_CP029629.1\|WP_000120367.1\|2075842_2076850_-\|inorganic-phosphate-transporter	unknown	unknown	gnl\|CDD\|376541
NZ_CP029629.1\|WP_001259679.1\|2063478_2063922_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP029629.1\|WP_000358498.1\|2060155_2060839_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234750

Protein	Function_ID	Function_description	E-value
NZ_CP029629.1\|WP_000820892.1\|2061301_2061868_+\|TIGR00730-family-Rossman-fold-protein	gnl\|CDD\|224527	COG1611, COG1611, Predicted Rossmann fold nucleotide-binding protein [General function prediction only].	1.24037e-61
NZ_CP029629.1\|WP_001129752.1\|2070605_2072756_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	2.12683e-20
NZ_CP029629.1\|WP_000367063.1\|2065321_2066542_-\|sugar-efflux-transporter	gnl\|CDD\|341024	cd17471, MFS_Set, Sugar efflux transporter (Set) family of the Major Facilitator Superfamily of transporters. This family is composed of sugar transporters such as Escherichia coli Sugar efflux transporter SetA, SetB, SetC and other sugar transporters. SetA, SetB, and SetC are involved in the efflux of sugars such as lactose, glucose, IPTG, and substituted glucosides or galactosides. They may be involved in the detoxification of non-metabolizable sugar analogs. The Set family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.30756e-101
NZ_CP029629.1\|WP_000731641.1\|2074457_2075255_+\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.44834e-40
NZ_CP029629.1\|WP_000833486.1\|2068721_2069195_-\|cupin-domain-containing-protein	gnl\|CDD\|226072	COG3542, COG3542, Uncharacterized conserved protein [Function unknown].	7.22926e-75
NZ_CP029629.1\|WP_000152582.1\|2064836_2065325_-\|DUF456-domain-containing-protein	gnl\|CDD\|225395	COG2839, COG2839, Uncharacterized protein conserved in bacteria [Function unknown].	4.76789e-44
NZ_CP029629.1\|WP_001090985.1\|2070100_2070460_-\|HTH-type-transcriptional-regulator-SarX	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.54609e-22
NZ_CP029629.1\|WP_000865624.1\|2067724_2068369_-\|DUF402-domain-containing-protein	gnl\|CDD\|225188	COG2306, COG2306, Predicted RNA-binding protein, associated with RNAses E/G family [General function prediction only].	1.46792e-91
NZ_CP029629.1\|WP_000532966.1\|2069194_2069911_-\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|237084	PRK12378, PRK12378, YebC/PmpR family DNA-binding transcriptional regulator.	8.8628e-136
NZ_CP029629.1\|WP_000148828.1\|2060841_2061300_+\|YaiI/YqxD-family-protein	gnl\|CDD\|178882	PRK00124, PRK00124, YaiI/YqxD family protein.	1.18273e-77
NZ_CP029629.1\|WP_000638621.1\|2061963_2062506_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	3.26713e-28
NZ_CP029629.1\|WP_000687412.1\|2066742_2067609_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	4.04787e-39
NZ_CP029629.1\|WP_000081602.1\|2073452_2074097_-\|Bax-inhibitor-1-family-protein	gnl\|CDD\|223742	COG0670, COG0670, Integral membrane protein, interacts with FtsH [General function prediction only].	1.16188e-32
NZ_CP029629.1\|WP_000120367.1\|2075842_2076850_-\|inorganic-phosphate-transporter	gnl\|CDD\|376541	pfam01384, PHO4, Phosphate transporter family. This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.	1.90489e-104
NZ_CP029629.1\|WP_001259679.1\|2063478_2063922_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	6.77401e-13
NZ_CP029629.1\|WP_000358498.1\|2060155_2060839_+\|hypothetical-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	0.000491798

>NZ_CP029629.1|WP_000367063.1|2065321_2066542_-|sugar-efflux-transporter
MDMFAALLQIKNYKLFVANMFLLGMGIAVTVPYLVLFATKDLGMTTNQYGLLLASAAISQFTVNSIIARFSDTHHFNRKIIIILALLMGALGFSIYFFVDTIWLFILLYAIFQGLFAPAMPQLYASARESINVSSSKDRAQFANTVLRSMFSLGFLFGPFIGAQLIGLKGYAGLFGGTISIILFTLVLQVFFYKDLNIKHPISTQQHVEKIAPNMFKDKTLLLPFIAFILLHIGQWMYTMNMPLFVTDYLKENEQHVGYLASLCAGLEVPFMIILGVLSSRLHTRTLLIYGAIFGGLFYFSIGVFKNFYMMLAGQVFLAIFLAVLLGIGISYFQDILPDFPGYASTLFSNAMVIGQLGGNLLGGAMSHWVGLENVFFVSAASIMLGMILIFFTKNQKITKEDVIST
>NZ_CP029629.1|WP_000152582.1|2064836_2065325_-|DUF456-domain-containing-protein
MTIILWLLIIAAFMLAFVGLIKPIIPSVLVLWVGFLIYQFGFHNQHLSWVFYVSMALLTILILCADFLANKYFVNRFGGSKFGEYAALIGVVIGCFVLPPFGIIIIPFILVFIVELIQGYSFERAVKVSIGSIVAFLTSSIAQAIIMFIMIVWFFIDALLIN
>NZ_CP029629.1|WP_000842860.1|2064048_2064738_+|DUF1129-family-protein
MKSTAQLTKENNVKSLRLSNTDREIFENYMTYMRSDFRVNPHDTELIINRILKQLLSAEQHGLLALDFFNHDPKAHAIKELKAMPNETFKNIFKYIYQHIVLLIGIVSFLKGFLGFFMEKNGSNLYFVSFPFSVVVGFFIVFLFIWFSFKTIQLQCFNNSNWIWIFTYLAIILLIVGFFYVFFIPQSLLAFGPYIQVSNWVFIIFSFIVMPIGLRIERNISKKHSHTFL
>NZ_CP029629.1|WP_001259679.1|2063478_2063922_-|GNAT-family-N-acetyltransferase
MRTLNKDEHNYIKQIANIHETLLSQVESNYKCTKLSIALRYEMICSRLEHTNDKIYIYENEGQLIAFIWGHFSNEKSMVNIELLYVEPQFRKLGIATQLKIALEKWAKTMNAKRISSTIHKNNLPMISLNKDLGYQVSHVKMYKDID
>NZ_CP029629.1|WP_000733433.1|2063022_2063412_-|hypothetical-protein
MKKLIISIMAVMLFLTGCGKSQEKATLEKDIDNLQKENKELKDKKEKLQQEKEKLADKQKDLEKEVKDLKPSKEDNKDDKKDEDKNKDKDKEASQDKQSKDQIKSSDKDNHKKPTSTDKDQKANDKHQS
>NZ_CP029629.1|WP_069993378.1|2062573_2062885_-|hypothetical-protein
MHEQDFRILEGQDITLPELGRELENITGRTIADSTGEIKRVIAHLPNFESDTDTFVATYRLNHQQDFIDATFTALKSDRARLKEVPVHVELISYISKSKQTAI
>NZ_CP029629.1|WP_000638621.1|2061963_2062506_-|GNAT-family-N-acetyltransferase
MIYCETERLILRDWHEDDLLPFQKMNANYDVRKYFPSLLSYRRSELDMRTMDAVIKDYGIGLFAVEDKETHQWIGFIGLNYIPETSDYPFKELPLYEIGWRLLPEFWGKGLATEGAKATLKLAEQHQIYDVYSFTAEANKASQRVMEKIGMTVYDHFELPNLSKYHLLKRQVRYYINLRK
>NZ_CP029629.1|WP_000820892.1|2061301_2061868_+|TIGR00730-family-Rossman-fold-protein
MKRIAVYCGASKGHDPSYVQKAYDLGKYFAEQGYELVFGAGSIGIMGAIQDGVLDHGGKAIGVMPKMLDEHEITSQRLTELILVDSMHERKNKMAELADAFVMAPGGAGSLEEFFEMYSWAQIGIHEKPIAIYNINGFFNPLQTMIDHMIEEGFIDPKYRALAPLCDTKESLIESILNFKPLGTRSYD
>NZ_CP029629.1|WP_000148828.1|2060841_2061300_+|YaiI/YqxD-family-protein
MTHIIIDGDACPVVDSIIDLTTETGIFVTIIRSFSHFSNQLYPPHVSTLYVDDGPDAVDYKIVQLSTKDDIVVTQDYGLASLLVDKVLIVMHHNGKIYNSKNIQQLLDKRYMNAQIRKQGGRHKGPPPFTKQDQKVFEQSLLKVIHRIKELD
>NZ_CP029629.1|WP_000358498.1|2060155_2060839_+|hypothetical-protein
MDKKKVIKFMINVLPIVLVPLIVERKRIKQHPDVQKVTDATSKVASKTSAAISNTASDVKEYVGDKKQDFENKRELKKFAREHDPAYIEKKGEKLAKQNRKDADKMNKILQKNIEKRHKEEQKAREKNEIQRIKDMKKSQKYEEKAGLTPNKLDEKTEKKGDKLAEKNRKEIAKMNKKLQKNIEKRHKEEQKRQQEADKARIKSFKKYKDYVAKSASQQNKENNTEA
>NZ_CP029629.1|WP_000687412.1|2066742_2067609_-|LysR-family-transcriptional-regulator
MKIEDYRLLITLDETKTLRKAAEILYISQPAVTQRLKAIENAFGVDIFIRTKKQLITTTEGTMIIEHARDMLKRERLFFDKMQAHIGEVNGTISIGCSSLIGQTLLPEVLSLYNAQFPNVEIQVQVGSTEQIKANHRDYHVMITRGNKVMNLANTHLFNDDHYFIFPKNRRDDVTKLPFIEFQADPIYINQIKQWYNDNLEQDYHATITVDQVATCKEMLISGVGVTILPEIMMKNISKEQFEFEKVEIDNEPLIRSTFMSYDPSMLQLPQVDSFVNLMASFVEQPKA
>NZ_CP029629.1|WP_000865624.1|2067724_2068369_-|DUF402-domain-containing-protein
MKVKYIDKRHWRRLIDREYTEVKVNNNRFKGIIGLVTMKKVRDPLEVTVVGQNIIVADDNYKWLQILPEKKRYSITVMFDNKGNPLEYYFDINIKNITQKGNARTVDLCLDVLALPSGEYELVDEDDLMFALESEQITKKQFHEAYMIAHQIMAELENDFKGFQKKIMYCFNKINAKAQKNHQKPQNKTNIEKSKQIKPKQYNQTKNHQQQKKN
>NZ_CP029629.1|WP_001789973.1|2068513_2068630_-|hypothetical-protein
MLQLFLMKIALNDFENDKSVLFIFLKNHFYEEMCVLSN
>NZ_CP029629.1|WP_000833486.1|2068721_2069195_-|cupin-domain-containing-protein
MKSAEQWIDELQLESHPEGGFYRETIREVLKDGRRAPFSSIYFLLTDDNISHFHRIDADEVWYYHAGDSLTIHMINPDGEYTTATLGTDIQNGDVLQYVVPKGTIFASSIEISNTYSLVGCMCQPAFEFKQFELFKQSELITQYPHLKSVIEKYALK
>NZ_CP029629.1|WP_000532966.1|2069194_2069911_-|YebC/PmpR-family-DNA-binding-transcriptional-regulator
MGRKWNNIKEKKAQKDKNTSRIYAKFGKEIYVAAKSGEPNPESNQALRLVLERAKTYSVPNHIIEKAIDKAKGAGDENFDHLRYEGFGPSGSMLIVDALTNNVNRTASDVRAAFGKNGGNMGVSGSVAYMFDHVATFGIEGKSVDEILETLMEQDVDVNDVIDDNGLTIVYAEPDQFAVVQDALRAAGVEEFKVAEFEMLPQTDIELSEADQVTFEKLIDALEDLEDVQNVFHNVDLK
>NZ_CP029629.1|WP_001090985.1|2070100_2070460_-|HTH-type-transcriptional-regulator-SarX
MNTEKLETLLGFYKQYKALSEYIDKKYKLSLNDLAVLDLTMKHCKDEKVLMQSFLKTAMDELDLSRTKLLVSIRRLIEKERLSKVRSSKDERKIYIYLNNDDISKFNALFEDVEQFLNI
>NZ_CP029629.1|WP_001129752.1|2070605_2072756_-|helix-turn-helix-transcriptional-regulator
MAKSCLHILTNNEYATTRCQDGIVLFWPIDGEIELQKFRKSKIIEDDIYIINHLDVFSIKNNKKTIMLYLSSDWFAELGFTFFNYHYTAKLIKSSYNLKCLLLKLTYRYLDNQPLNDADIRKLQDIIKIIAKEASMDKKIAQNQYRYAYYGDLRDELEYIYQNVNQRLTLKSVADKLFVSKSNLSSQFHLLMGMGFKKYIDTLKIGKSIEILLTTDSTISNISEHLGFSSSSTYSKMFKSYMDITPNEYRNLSKYNKCLMLKPEPLVGKMVQEVKEIILNYIEHYKNHLTDVIHIDEDKFETPKLFQTVIQINTYTEMKLVFLEGIFKTLLNKNSQVVFFIMPSILKSKNTMSEEEKFTIIKTIIESDLKIAFNINDIETTYFVEEAFMSVFRQISPNELSNHNNYEVHFVFDLSLMEIRTIYRMILKLHNIMLNVKLGLNITCLFEKPSVFKSLVSQIKRLKFDSLIIDNANLSSPYLMGESDELLLKNILHFKNLKQVINELDIEQEKLIFLNVENHKLLNNKERDLSNSAPLIYKTLSALYHNFDGFGLNIFDNHQAFNAMHLYDKNGFKTTLGLILEKFIEYVSKPKYENSYYSIFDIENYYCLVIYDWRVIESETIMSNFEDSQVYINFKNNVLNDKYLIVIETLDENSGNINHLISKELRDKYEWNPSLLSKIDNYLKPAIEIKEHNFSDNSLNINVTFNALYIIKIGKK
>NZ_CP029629.1|WP_000081602.1|2073452_2074097_-|Bax-inhibitor-1-family-protein
MSQNTNHSYYHQNQHAQSISKVWLYFMYYWIIFGIGCYLGQFLPLSWRQPLSFGLLIIILATLVFERARRFGLIISHIYAVVIGLLSYATFTTYLQNLGPDIFYKNIALAIFAFIAFGIIGYFFVGDASSIGKYLFVTLITLIIASLIGIFLQNPIFYTIITVVSLLLFLLYTLYDFNRLKRGDYSPREMGFNLFINLLNIIKDILYLANMFRR
>NZ_CP029629.1|WP_000731641.1|2074457_2075255_+|LysM-peptidoglycan-binding-domain-containing-protein
MKKLAFAITATSGAAAFLTHHDAQASTQHTVQSGESLWSIAQKYNTSVESIKQNNQLDNNLVFPGQVISVGGSDAQNSSNTSPQAGSASSHTVQAGESLNIIASRYGVSVDQLMAANNLRGYLIMPNQTLQIPNGGSGGTTPTATTGSNGNASSFNHQNLYTAGQCTWYVFDRRAQAGSPISTYWSDAKYWAGNAANDGYQVNNTPSVGSIMQSTPGPYGHVAYVERVNGDGSILISEMNYTYGPYNMNYRTIPASEVSSYAFIH
>NZ_CP029629.1|WP_000120367.1|2075842_2076850_-|inorganic-phosphate-transporter
MSYIIIVTIAVVIFSLIFDFINGFHDTANAVATAVSTRALTPKTAILMAAVMNFIGALTFTGVAGTITKDIVDPFKLENGLVVVLAAILAAIIWNLATWFYGIPSSSSHALIGSIAGAAIASEGSFGVLHYQGFTKIIIVLIVSPIIAFCVGFLMYSIFKVIFKNANLTRANRNFRFFQIFTAALQSFSHGTNDAQKSMGIITLALIVANVQNDGSVEPQLWVKFACATAMGLGTAIGGWKIIKTVGGNIMKIRPANGAAADLSSALTIFVASSLHFPLSTTHVVSSSILGVGASNRAKGVKWSTAQRMIITWVITLPISALLACLLFYILNLFF

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Crispr_ID: NZ_CP029629_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP029629_7

2129323-2129416

Orphan

Consensus_repeat	Method
GGCTTTTATGCAGTTGCTGCACAAACAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP029629_7

>merge|NZ_CP029629|7|2129323-2129416|CRISPRCasFinder
GGCTTTTATGCAGTTGCTGCACAAACAACTGTATTCCTTTACTCCCCTTGAGCTTTAGCGATTAGGGGCTCTTATGCAGTTGCTGCACAAACAA

>NZ_CP029629|7|7|2129323-2129416|CRISPRCasFinder
GGCTTTTATGCAGTTGCTGCACAAACAA	CTGTATTCCTTTACTCCCCTTGAGCTTTAGCGATTAGG
GGCTCTTATGCAGTTGCTGCACAAACAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP029629.1\|WP_070001927.1\|2132849_2133860_-\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|181842
NZ_CP029629.1\|WP_000655099.1\|2132667_2132775_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029629.1\|WP_110161696.1\|2136887_2137424_-\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
NZ_CP029629.1\|WP_000901764.1\|2129531_2130167_-\|endonuclease-III-domain-containing-protein	unknown	unknown	gnl\|CDD\|225140
NZ_CP029629.1\|WP_110161695.1\|2136242_2136719_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP029629.1\|WP_001788287.1\|2134358_2134880_-\|YwhD-family-protein	unknown	unknown	gnl\|CDD\|378039
NZ_CP029629.1\|WP_070046575.1\|2123194_2123983_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP029629.1\|WP_001790232.1\|2127229_2128180_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NZ_CP029629.1\|WP_001021145.1\|2130500_2132162_-\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
NZ_CP029629.1\|WP_000365354.1\|2126455_2127175_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223943
NZ_CP029629.1\|WP_000749059.1\|2128327_2129215_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238563
NZ_CP029629.1\|WP_000169043.1\|2120274_2120499_+\|DUF2922-domain-containing-protein	unknown	unknown	gnl\|CDD\|378571
NZ_CP029629.1\|WP_000808902.1\|2137634_2138573_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381309
NZ_CP029629.1\|WP_000359086.1\|2132158_2132575_-\|DUF1934-domain-containing-protein	unknown	unknown	gnl\|CDD\|226896
NZ_CP029629.1\|WP_001808006.1\|2120692_2121622_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|225778
NZ_CP029629.1\|WP_000362967.1\|2125671_2126472_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP029629.1\|WP_000735558.1\|2125029_2125536_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029629.1\|WP_001222133.1\|2124151_2124868_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029629.1\|WP_000180230.1\|2134907_2136203_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
NZ_CP029629.1\|WP_001018677.1\|2122569_2122944_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|130944

Protein	Function_ID	Function_description	E-value
NZ_CP029629.1\|WP_070001927.1\|2132849_2133860_-\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0
NZ_CP029629.1\|WP_110161696.1\|2136887_2137424_-\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	4.75153e-26
NZ_CP029629.1\|WP_000901764.1\|2129531_2130167_-\|endonuclease-III-domain-containing-protein	gnl\|CDD\|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	3.98158e-90
NZ_CP029629.1\|WP_110161695.1\|2136242_2136719_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13315e-11
NZ_CP029629.1\|WP_070046575.1\|2123194_2123983_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.22673e-34
NZ_CP029629.1\|WP_001790232.1\|2127229_2128180_-\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	5.19191e-48
NZ_CP029629.1\|WP_001021145.1\|2130500_2132162_-\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
NZ_CP029629.1\|WP_000749059.1\|2128327_2129215_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238563	cd01143, YvrC, Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	8.54601e-73
NZ_CP029629.1\|WP_000169043.1\|2120274_2120499_+\|DUF2922-domain-containing-protein	gnl\|CDD\|378571	pfam11148, DUF2922, Protein of unknown function (DUF2922). This bacterial family of proteins has no known function.	5.21775e-14
NZ_CP029629.1\|WP_000808902.1\|2137634_2138573_-\|aldo/keto-reductase	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	7.3194e-168
NZ_CP029629.1\|WP_000359086.1\|2132158_2132575_-\|DUF1934-domain-containing-protein	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	2.62525e-58
NZ_CP029629.1\|WP_001808006.1\|2120692_2121622_+\|DMT-family-transporter	gnl\|CDD\|225778	COG3238, COG3238, Uncharacterized protein conserved in bacteria [Function unknown].	8.35021e-36
NZ_CP029629.1\|WP_000362967.1\|2125671_2126472_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	7.17592e-26
NZ_CP029629.1\|WP_001788287.1\|2134358_2134880_-\|YwhD-family-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	8.7406e-98
NZ_CP029629.1\|WP_000365354.1\|2126455_2127175_-\|HAD-family-hydrolase	gnl\|CDD\|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	3.6864e-38
NZ_CP029629.1\|WP_000180230.1\|2134907_2136203_-\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.70707e-150
NZ_CP029629.1\|WP_001018677.1\|2122569_2122944_+\|transcriptional-regulator	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.77309e-26

>NZ_CP029629.1|WP_000749059.1|2128327_2129215_-|ABC-transporter-substrate-binding-protein
MKKSLIAFILIFMLVLSGCGMKDNDKQGSNDNGSSKSPYHRIVSLMPSNTEILYELGLGKYIVGVSTVDDYPKDVKKGKKQFDALNLNKEELLKAKPDLILAHESQKATANKVLSSLEKQGIKVVYVKDAQSIDETYNTFKQIGKLTHHDKQAEQLVEETKDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGWNPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSRPGPRIDEGLKELRDAIYRK
>NZ_CP029629.1|WP_001790232.1|2127229_2128180_-|iron-ABC-transporter-permease
MTFNKVLLSWIVILIITTSIYLFWQLGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPVFSITFSLITLITVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGRQLALNIVTGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKRLH
>NZ_CP029629.1|WP_000365354.1|2126455_2127175_-|HAD-family-hydrolase
MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQLADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTLYTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFEDMIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVEELLTILPIKNDNKGENYGSIY
>NZ_CP029629.1|WP_000362967.1|2125671_2126472_-|alpha/beta-hydrolase
MDLFTRKDGTSIHYSTLGEGYPIVLIHTVLDNYSVFNKLAAELAKSFQVVLIDLRGHGYSDKPRHIEIKDFSDDIVELLKYLYIEEVAFVCHEMGGIIGADISVRYPEFTSSLTLVNPTSIEGELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRKMNRFLKHVVDTNEISTKEEIQAVKEVFKNADISQTYRNVVVPTKIIAGEFGERTTRLEAKEVADLIQNADFEVYQESSAFPFVEEQERFVEDTAAFINKHHDEKHV
>NZ_CP029629.1|WP_000735558.1|2125029_2125536_-|hypothetical-protein
MKKLLTASIIACSVVMGVGLVNTSAEAASGNSIDTVKQLIKGDQSLENVKIGESIKDVLTKYKNPMYSYNEDGTEHYYEFHTKKGMLLVTTDGKKNNGKVTHISMMYNDANGPTYQAVKNYVGKAVTHTEYSKVAGNFGYIEKGKTTYQFASAPKDKNIKLYRIDLEK
>NZ_CP029629.1|WP_001222133.1|2124151_2124868_-|hypothetical-protein
MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVITDIKNSEKKDQDYIEYKRKSPAQIILMIQRNLFALQMNPVIFFIINFILISYLYDKQYVQFQAITGMSLFYCLVIFPMTIVVYLRVSQKNYLRSNKIEMIMGTIIAIISLLLIILQAFNITWGVIPITNFGHQFFFFIGIILVIAGIFYKRLEFSGIGLLFCQKTVDAMIHNPQSAQIFSLIIWILLVVLVIYFTIRLSSRTRL
>NZ_CP029629.1|WP_070046575.1|2123194_2123983_-|alpha/beta-hydrolase
MNKVTINPQIQLTYQIEGKGDPIILLHGLDGNLAGFEDLQHQLASSYKVLTYDLRGHGKSSKSESYDLNDQVEDLKILMEKLNIHEAHILGHDLGGVVAKLFTDKYAYRVKSLTTIASKKDDLIHSFTQLLIQYQDDIAGFNKSEAYILLFSKLFRNQEKTMKWYQKQRIYSIKSEDDSAVAIRSLILHKDEPMYLKKRTCVPTLLINGEHDPLIKDKNHFKLEAHFLNVTKKIFEHSGHAPHIEEPEAFMNYYLKFLKSVS
>NZ_CP029629.1|WP_001018677.1|2122569_2122944_+|transcriptional-regulator
MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLSRVNKRITEANNEIEL
>NZ_CP029629.1|WP_001808006.1|2120692_2121622_+|DMT-family-transporter
MLLFYIIGVLVGMLIPIQTSVNSRLSLYTKSPFYTSFISFSVGTICLIILNIIINPKVFTIHFYNNQSFNYTWVVGGLLGVSFLTGNLLLLPKLGATLTVIATVAGQIIMGVIIDTLGLFGATIHDFNLIKAIGVLLLIIGIVIMNQFNKNNLLLTDQKYLLFWLLLGFIFGFFPPIQTTINSALASHTHSPAFASLVSFTIGSIALLILTAIFNRSLKLKTSHLKFGKLKPIYFTGGILGMAFVTANIILMPHMGAALTTLIGMFGQILMGILIDHFGLFGSPKIAMTSRKTIGLLCILTGIILLRLF
>NZ_CP029629.1|WP_000169043.1|2120274_2120499_+|DUF2922-domain-containing-protein
MTKTLELSFKSSLDKPVKLQLPQLNNVVTEQVVRDSMNALVDLNIIKSNSGTITKVHSAQIIDKTTTVLFEDKK
>NZ_CP029629.1|WP_000901764.1|2129531_2130167_-|endonuclease-III-domain-containing-protein
MLGTDELYKVLYEHLGPQFWWPADNDIEMMLGAILVQNTRWRNAEIALNQIKEHTHFNPNHILELPIETLQSLIHSSGFYKSKSLTIKTLLTWLARHHFNYQEINERYKGGLRKELLSLKGIGSETADVLLVYIFGRIEFIPDSYTRKIYDKLGYENTKNYDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK
>NZ_CP029629.1|WP_001021145.1|2130500_2132162_-|arginine--tRNA-ligase
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>NZ_CP029629.1|WP_000359086.1|2132158_2132575_-|DUF1934-domain-containing-protein
MDKKVSIQTKQVLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLEVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>NZ_CP029629.1|WP_000655099.1|2132667_2132775_-|hypothetical-protein
MKDSENLVFFGFEVLFVFYKMAYIYEALIKYGIVN
>NZ_CP029629.1|WP_070001927.1|2132849_2133860_-|alcohol-dehydrogenase-AdhP
MRAAVVTKDHKVNIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>NZ_CP029629.1|WP_001788287.1|2134358_2134880_-|YwhD-family-protein
MEVISLSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGMWKHSSDALHQAFN
>NZ_CP029629.1|WP_000180230.1|2134907_2136203_-|HD-domain-containing-protein
MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVAPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>NZ_CP029629.1|WP_110161695.1|2136242_2136719_-|GNAT-family-N-acetyltransferase
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNEGLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKEF
>NZ_CP029629.1|WP_110161696.1|2136887_2137424_-|flavodoxin-family-protein
MITVLFGGSRPNGNTAQLTKFALRDLEYQWIDVTQHQFKPIRDVRHTAETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDIMKDNYALARATEWNSILQ
>NZ_CP029629.1|WP_000808902.1|2137634_2138573_-|aldo/keto-reductase
MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKDVVRQAINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQPEYLKQQVENSLKRLQTDYIDLYYIHFPDNNTPKDQAVAALQELKEQGKIKAIGVSNFTLDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHQITFIPYFPLASGILAGKYDENTKFSDHRTTRRDFKPGVFEENVRRVKALESIAAAHQTSIANIVLAFYLTRPAIDVIIPGAKRAEQVVENIKAADIVLSDDEIQYIDELFPIED

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Crispr_ID: NZ_CP029629_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP029629_8

2650398-2650479

Orphan

Consensus_repeat	Method
TTCTACAGGCAATGCAAGTTGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP029629_8

>merge|NZ_CP029629|8|2650398-2650479|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGATGGGCCCCAACACAGAGAAATTGGATTCCCAATTTCTACAGACAATGCAAGTTGGGG

>NZ_CP029629|8|8|2650398-2650479|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGG	ATGGGCCCCAACACAGAGAAATTGGATTCCCAAT
TTCTACAGACAATGCAAGTTGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP029629.1\|WP_000616225.1\|2650583_2650961_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|226134
NZ_CP029629.1\|WP_000751267.1\|2645686_2646388_-\|lytic-transglycosylase-IsaA	unknown	unknown	gnl\|CDD\|381607
NZ_CP029629.1\|WP_001789900.1\|2648461_2649031_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP029629.1\|WP_000725233.1\|2641471_2642239_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP029629.1\|WP_000055859.1\|2651818_2652118_-\|DUF2316-family-protein	unknown	unknown	gnl\|CDD\|226806
NZ_CP029629.1\|WP_000651837.1\|2650977_2651799_-\|NmrA/HSCARG-family-protein	unknown	unknown	gnl\|CDD\|187561
NZ_CP029629.1\|WP_001224182.1\|2652249_2652807_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP029629.1\|WP_000200684.1\|2646996_2648052_-\|PTS-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226167
NZ_CP029629.1\|WP_001791985.1\|2648178_2648307_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP029629.1\|WP_000379818.1\|2642599_2644411_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|224748
NZ_CP029629.1\|WP_000996736.1\|2644922_2645411_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
NZ_CP029629.1\|WP_000706519.1\|2655597_2656488_-\|GTP-binding-protein	unknown	unknown	gnl\|CDD\|223597
NZ_CP029629.1\|WP_001163740.1\|2657918_2659025_-\|NAD(P)-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|379355
NZ_CP029629.1\|WP_001795496.1\|2640808_2641297_-\|glycosyl-4,4'-diaponeurosporenoate-acyltransferase	unknown	unknown	unknown
NZ_CP029629.1\|WP_000895193.1\|2656584_2657925_-\|ferrous-iron-transporter-B	unknown	unknown	gnl\|CDD\|223447
NZ_CP029629.1\|WP_000697134.1\|2649949_2650180_+\|DUF896-domain-containing-protein	unknown	unknown	gnl\|CDD\|226677
NZ_CP029629.1\|WP_000161829.1\|2652799_2653504_+\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|187585
NZ_CP029629.1\|WP_000160466.1\|2639322_2640816_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224154
NZ_CP029629.1\|WP_000836425.1\|2653590_2654601_+\|amidohydrolase	unknown	unknown	gnl\|CDD\|225070
NZ_CP029629.1\|WP_000448899.1\|2654620_2655451_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669

Protein	Function_ID	Function_description	E-value
NZ_CP029629.1\|WP_000616225.1\|2650583_2650961_-\|VOC-family-protein	gnl\|CDD\|226134	COG3607, COG3607, Predicted lactoylglutathione lyase [General function prediction only].	1.45544e-58
NZ_CP029629.1\|WP_000751267.1\|2645686_2646388_-\|lytic-transglycosylase-IsaA	gnl\|CDD\|381607	cd13925, RPF, core lysozyme-like domain of resuscitation-promoting factor proteins. Resuscitation-promoting factor (RPF) proteins, found in various (G+C)-rich Gram-positive bacteria, act to reactivate cultures from stationary phase. This protein shares elements of the structural core of lysozyme and related proteins. Furthermore, it shares a conserved active site glutamate which is required for activity, and has a polysaccharide binding cleft that corresponds to the peptidoglycan binding cleft of lysozyme. Muralytic activity of Rpf in Micrococcus luteus correlates with resuscitation, supporting a mechanism dependent on cleavage of peptidoglycan by RPF.	3.60255e-06
NZ_CP029629.1\|WP_001789900.1\|2648461_2649031_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.43347e-07
NZ_CP029629.1\|WP_000725233.1\|2641471_2642239_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.0489e-31
NZ_CP029629.1\|WP_000055859.1\|2651818_2652118_-\|DUF2316-family-protein	gnl\|CDD\|226806	COG4367, COG4367, Uncharacterized protein conserved in bacteria [Function unknown].	1.06282e-39
NZ_CP029629.1\|WP_000651837.1\|2650977_2651799_-\|NmrA/HSCARG-family-protein	gnl\|CDD\|187561	cd05251, NmrA_like_SDR_a, NmrA (a transcriptional regulator) and HSCARG (an NADPH sensor) like proteins, atypical (a) SDRs. NmrA and HSCARG like proteins. NmrA is a negative transcriptional regulator of various fungi, involved in the post-translational modulation of the GATA-type transcription factor AreA. NmrA lacks the canonical GXXGXXG NAD-binding motif and has altered residues at the catalytic triad, including a Met instead of the critical Tyr residue. NmrA may bind nucleotides but appears to lack any dehydrogenase activity. HSCARG has been identified as a putative NADP-sensing molecule, and redistributes and restructures in response to NADPH/NADP ratios. Like NmrA, it lacks most of the active site residues of the SDR family, but has an NAD(P)-binding motif similar to the extended SDR family, GXXGXXG. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Atypical SDRs are distinct from classical SDRs. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	6.56436e-84
NZ_CP029629.1\|WP_001224182.1\|2652249_2652807_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	9.50396e-13
NZ_CP029629.1\|WP_000200684.1\|2646996_2648052_-\|PTS-transporter-subunit-IIC	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	5.38046e-117
NZ_CP029629.1\|WP_000379818.1\|2642599_2644411_-\|acetyltransferase	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	8.15616e-84
NZ_CP029629.1\|WP_000996736.1\|2644922_2645411_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.6785e-11
NZ_CP029629.1\|WP_000706519.1\|2655597_2656488_-\|GTP-binding-protein	gnl\|CDD\|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	2.17569e-76
NZ_CP029629.1\|WP_001163740.1\|2657918_2659025_-\|NAD(P)-binding-domain-containing-protein	gnl\|CDD\|379355	pfam13738, Pyr_redox_3, Pyridine nucleotide-disulphide oxidoreductase.	4.45347e-126
NZ_CP029629.1\|WP_000161829.1\|2652799_2653504_+\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|187585	cd05324, carb_red_PTCR-like_SDR_c, Porcine testicular carbonyl reductase (PTCR)-like, classical (c) SDRs. PTCR is a classical SDR which catalyzes the NADPH-dependent reduction of ketones on steroids and prostaglandins. Unlike most SDRs, PTCR functions as a monomer. This subgroup also includes human carbonyl reductase 1 (CBR1) and CBR3. CBR1 is an NADPH-dependent SDR with broad substrate specificity and may be responsible for the in vivo reduction of quinones, prostaglandins, and other carbonyl-containing compounds. In addition it includes poppy NADPH-dependent salutaridine reductase which catalyzes the stereospecific reduction of salutaridine to 7(S)-salutaridinol in the biosynthesis of morphine, and Arabidopsis SDR1,a menthone reductase, which catalyzes the reduction of menthone to neomenthol, a compound with antimicrobial activity; SDR1 can also carry out neomenthol oxidation. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	4.08524e-67
NZ_CP029629.1\|WP_000895193.1\|2656584_2657925_-\|ferrous-iron-transporter-B	gnl\|CDD\|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	1.90855e-93
NZ_CP029629.1\|WP_000697134.1\|2649949_2650180_+\|DUF896-domain-containing-protein	gnl\|CDD\|226677	COG4224, COG4224, Uncharacterized protein conserved in bacteria [Function unknown].	6.01061e-31
NZ_CP029629.1\|WP_000160466.1\|2639322_2640816_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	5.98974e-132
NZ_CP029629.1\|WP_000836425.1\|2653590_2654601_+\|amidohydrolase	gnl\|CDD\|225070	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only].	7.39377e-78
NZ_CP029629.1\|WP_000448899.1\|2654620_2655451_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.6811e-18

>NZ_CP029629.1|WP_000697134.1|2649949_2650180_+|DUF896-domain-containing-protein
MKILDRINELANKEKVQPLTVAEKQEQHALRQDYLSMIRGQVLTTFSTIKVVDPIGQDVTPDKVYDLRQQYGYIQN
>NZ_CP029629.1|WP_001789900.1|2648461_2649031_+|TetR/AcrR-family-transcriptional-regulator
MMESKSIDPRIVRTKQLLVDAFLKISREKKLSQITVKDITDIATLNRATFYAHFTDKEDLLDYTLSVTILKDLNDNLSISNVINEKVLRNIFISIASYIKDAAKSCELNSEAFCNKAHQRINNELEDIFAIMLENSYPEHQRDIIVNSASFLAAGISGLALHWFNTSQETADVFIDRNLPFLIHHIAHF
>NZ_CP029629.1|WP_001791985.1|2648178_2648307_-|hypothetical-protein
MDFKNEDKIKVYCNNMFEKLPISLSKNSEFCDILFFIVLSYR
>NZ_CP029629.1|WP_000200684.1|2646996_2648052_-|PTS-transporter-subunit-IIC
MTSIKTITPKDFIFRVLSGVAIGIVAGLVPNAILGEIFKYFMDYHPIFKTLLGVVVAIQFTVPALIGALVAMKFDLSPLAIAVVASAAYVGSGAAQFKNGAWMITGIGDLINTMITAAIAVLFILLIQHRVGSMALIVFPTVVGGISGAIGVLILPYTKMITTAIGNMVNGFTELQPIVMSILISMVFSLIIISPLSTVAIAFAIGITGLAAGSASIGISATEAVLIIGTSKVNRLGVPLSVFFGGVKMMIPNMVKYPILMLPILTTAIVSGLVSALVGIHGTKESAGFGFIGMVGPINAFKFMEVDSAWLSVLLIVVAFFVVPFVTAWLADIIYRKVFRLYTNDIFKFMG
>NZ_CP029629.1|WP_000751267.1|2645686_2646388_-|lytic-transglycosylase-IsaA
MKKTIMASSLAVALGVTGYAAGTGHQAHAAEVNVDQAHLVDLAHNHQDQLNAAPIKDGAYDIHFVKDGFQYNFTSNGTTWSWSYEAANGQTAGFSNVAGADYTTSYNQGSNVQSVSYNAQSSNSNVEAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSSAAQIMAQRTGVSASTWAAIIARESNGQVNAYNPSGASGLFQTMPGWGPTNTVDQQINAAVKAYKAQGLGAWGF
>NZ_CP029629.1|WP_000996736.1|2644922_2645411_-|GNAT-family-N-acetyltransferase
MAINIIEYNRSYKEELIEFILSIQKNEFNIKIDRDDQPDLENIEHNYLNNGGQFWLAINNHQNIVGTIGLIRLDNNMSALKKMFVDKGYRNLKIGKKLLDKVIMTCKEQNIDGIYLGTIDKFISAQYFYSNNGFREIKRGDLPSSFPKLDVDNRFYYRNLKD
>NZ_CP029629.1|WP_000379818.1|2642599_2644411_-|acetyltransferase
MDTKDFKRLEKMYSPRYLPGLDGLRAFAVIGIIIYHLNAQWLSGGFLGVDTFFVISGYLITSLLISEYYRTQKIDLLEFWKRRLKRLIPAVLFLICVVLTFTLIFKPELIIQMKRDAIAAIFYVSNWWYISQNVDYFNQFAIEPLKHLWSLAIEEQFYLLFPLVITFLLHRFKPRNIIQTLFIVSLISLGLMIVIHFITGDNSRVYFGTDTRLQTLLLGCILAFIWPPFALKKDISKKIVVSLDIIGISGFAVLMTLFFIVGDQDQWIYNGGFYIISFATLFIIAIAVHPSSLFAKFLSMKPLLIIGKRSYSLYLWHYPIIVFVNSYYVQGQIPVYVYIIEILLTALMAEISYRFIETPIRKKGFKAFAFLPKKKGQFARTVLVILLLVPSIVVLSGQFDALGKQHEAEKKEKKTEFKTMKKKVVKKDKQEDKQTANSKEDIKKSSPLLIGDSVMVDIGNVFTKKIPNAQIDGKVGRQLVDATPIVKSQYKDYAKKGQKVVVELGTNGAFTKDQLNELLDSFGKADIYLVSIRVPRDYEGRINKLIYEAAEKRSNVHLVDWYKASAGHPEYFAYDGIHLEYAGSKALTDLIVKTMETHATNKK
>NZ_CP029629.1|WP_000725233.1|2641471_2642239_-|CHAP-domain-containing-protein
MKKIVTATIATAGLATIAFAGHDAQAVEQNNNGYNSNDAQSYSYTYTIDAQGNYHYTWTGNWNPSQLTQNNTYYYNNYNTYSYNNASYNNYYNHSYQYNNYTNNSQTATNNYYTGGSGASYSTTSNNVHVTTTAAPSSNGRSISNGYASGSNLYTSGQCTYYVFDRVGGKIGSTWGNASNWANAAASSGYTVNNTPKVGAIMQTTQGYYGHVAYVEGVNSNGSVRVSEMNYGHGAGVVTSRTISANQAGSYNFIH
>NZ_CP029629.1|WP_001795496.1|2640808_2641297_-|glycosyl-4,4'-diaponeurosporenoate-acyltransferase
MKKYIKTAFFCSMYWLIVQLNIANLGTRIPDKYFRQKYIIFKSFNFEKHGKFWNKWFYVRKWKHKILDGHQLNQNIYDQRHLMTINTDEIEKMIIETKRAELIHWISILPVIIFNKGPRLVKYINIFYAMIANVPIIIVQRYNRPRLTQLLRILKRRGERHD
>NZ_CP029629.1|WP_000160466.1|2639322_2640816_-|NAD(P)/FAD-dependent-oxidoreductase
MTKHIIVIGGGLGGISAAIRMAQSGYSVSLYEQNNHIGGKVNRHESDGFGFDLGPSILTMPYIFEKLFEYSKKQMSDYVTIKRLPHQWRSFFPDGTTIDLYEGIKETGQHNVILSKQDIEELQNYLNYTRRIDRITEKGYFNYGLDTLSQIIKFHGPLNALINYDYVHTMQQAIDKRISNPYLRQMLGYFIKYVGSSSYDAPAVLSMLFHMQQEQGLWYVEGGIHHLANALEKLAREEGVTIHTGARVDNIKTYQRRVTGVRLDTGEFVKADYIISNMEVIPTYKYLLHLDTQRLNKLEREFEPASSGYVMHLGVACQYPQLAHHNFFFTENAYLNYQQVFHEKVLPDDPTIYLVNTNKTDHTQAPVGYENIKVLPHIPYIQDQPFTTEDYAKFRDKILDKLEKMGLTDLRKHIIYEDVWTPEDIEKNYRSNRGAIYGVVADKKKNKGFKFPKESQYFENLYFVGGSVNPGGGMPMVTLSGQQVADKINAREAKNRK
>NZ_CP029629.1|WP_000616225.1|2650583_2650961_-|VOC-family-protein
MIQSMWFNLHVQDLEKSAQFYKALGFKINRNPQMLDKMVGIQIGQTTVILIENKHFQNVSQQSLNTEPNEVMISLGVNTNEEVDQLVNKVKEAGGAVVQEPTVSQGFYGAMFKDLDGHHFNFLVC
>NZ_CP029629.1|WP_000651837.1|2650977_2651799_-|NmrA/HSCARG-family-protein
MKDILVIGATGKQGNAVVKQLLEDGWYVSALTRNKNNRKLSDIGHPHLSIVEGDLSDNVSLQSAMKGKYGLYSIQPIVKDDVSEELRQGMKIIEIAEQENIQHIVYSTAGGVNRNRTGPHFEVLAKIENRLMESNINATVIKPSFFMDNFLRIAKVEDERITLPEFINPNIKFTMISSIDIAKIASYIFAHPQSFTHQSIEIGSDEVTLSEAATIFSEVTGKSTVIEGEFVSGVAEKQWLEEKGYEVDFELMAEINPTRLSLSDWLKVQNYNK
>NZ_CP029629.1|WP_000055859.1|2651818_2652118_-|DUF2316-family-protein
MSLNKEQRRITCEELQAHFEASTLSVQMIAEKLNVTTEDVEKVLAMTAPLGIFSHQLQRFIHLVWDVRDVINDNIKGNGQTPEPYTYLKGEKEDYWFLR
>NZ_CP029629.1|WP_001224182.1|2652249_2652807_+|TetR/AcrR-family-transcriptional-regulator
MRKDAIENRQRIEEIAHKLFDEEGVENISMNRIAKELGIGMGTLYRHFKDKSDLCYYVIQRDLDIFITHFKQIKDDYHSNYEVMQVSLDYLLQFKIDNKALLQCIEAGNNKLRFYQSAFYQELFDFYYDLFKSDDDTYTKFKTDMLLQSLSTSVFAFQIEHRHISIEAYRNYLLNIYLDEVERND
>NZ_CP029629.1|WP_000161829.1|2652799_2653504_+|SDR-family-NAD(P)-dependent-oxidoreductase
MTKIVLITGGNKGLGYASAEALKALGYKVYIGSRNDVRGQQASQKLGVHYVQLDVTSDYSVKNAYNMIAEKEGRLDILINNAGISGQFSAPSKLTPRDVEEVYQTNVFGIVRMMNTFVPLLEKSEQPVVVNVSSGLGSFGMVTNPETAESKVNSLAYCSSKSAVTMLTLQYAKGLPNMQINAADPGATNTDLVGDFSNNSKHVSEGIKPIIQLATIGADGPTGTFINGDGEMPW
>NZ_CP029629.1|WP_000836425.1|2653590_2654601_+|amidohydrolase
MKSITFEEHYVIEDIQKETMNAISADPKGVPMKVMLEGLEKKTGFTNADELSHHDERIQFMNNQDVQIQVLSYGNGSPSNLVGQKAIELCQKANDQLANYIAQYPNRFVGFATLPINEPEAAAREFERCINDLGFKGALIMGRAQDGFLDQDKYDIIFKTAENLGVPIYLHPAPVNSDIYQSYYKGNYPEVTAATFACFGYGWHIDVGIHAIHLVLSGIFDRYPKLNMIIGHWGEFIPFFLERMDEALFAEHLNHPVSYYFKNNFYITPSGMLTKPQFDLVKKEVGIDRILYAADYPYIEPEKLGVFLDELGLTDEEKEKISYTNGAKLLGLSSNN
>NZ_CP029629.1|WP_000448899.1|2654620_2655451_+|alpha/beta-hydrolase
METLELQGAKLRYHQVGQGPVLIFIPGANGTGDIFLPLAEQLKDHFTVVAVDRRDYGESELTEPIPDSASNPDSDYRVKRDAQDIAELAKSLSDEPVYILGSSSGSIVAMHVLKDYPEVVKKIAFHEPPINTFLPDSTYWKDKNDDIVHQILTEGLEKGMKTFGETLNIAPIDAKMMSQPADTEEGRIEQYKRTMFWSKFEIRQYTHSDITLDDFTKYSDKITLLNGTDSRGSFPQDVNFYINKETGIPIVDIPGGHLGYIQKPEGFADVLLNLWG
>NZ_CP029629.1|WP_000706519.1|2655597_2656488_-|GTP-binding-protein
MKIVIIGGFLGGGKTTVLNHLLAESLKESLKPAVIMNEFGKMSVDGALVSEDIPLSELTEGCICCAMKADVSEQLHQLYLKEQPDIVFIECSGIAEPVSVLDACLTPILAPFTTITHMIGVIDASMYKHIKSFPKDIQGLFYEQLAYCSVLFVNKIDSADVETTSKLLKDLEVINPEADIQVGMHGSVTLPISVRQMTATSDNKHKSLHQMINHQFVQSPVKCTKAEFIKRLACLPSHIYRLKGFMTFEDTAHTYLIQFTQGQYELTPVAFSKKVPEYLVLIGKGISKEDYQCLEQ
>NZ_CP029629.1|WP_000895193.1|2656584_2657925_-|ferrous-iron-transporter-B
MLEVKYDMRTGHYTPIPNEPHYLVISHADKLTATEKAKLRLLIIKQKLDISLAESVVSSPIASEHVIEQLTLFQHERRHLRPKISATFLAWLLIFLMFALPIGIAYQFSDWFQNQYVSAWIEYLTQTTLLNHDILQHILFGDYGVLSLGTYSLVWALPVVILISLSTAIIDQTGLKSWMIWAIEPSMLRIGLQGNDIVPLLEGFGCNAAAISQAAHQCHTCTKTQCMSLISFGSSCSYQIGATLSIFSVAGKSWLFMPYLILVLLGGILHNRIWLKKNDQQLSVPLPYDRQLHMPNIRQMLLQMWQNIQMFIVQALPIFITICLIVSILSLTPILNVLSQIFTPILSLLGISSELSPGILFSMIRKDGMLLFNLHQGALLQGMTATQLLLLVFFSSTFTACSVTMTMLLKHLGGQSALKLIGKQMVTSLSLVIGVGIIVKIVMLII
>NZ_CP029629.1|WP_001163740.1|2657918_2659025_-|NAD(P)-binding-domain-containing-protein
MQHHKVAIIGAGAAGIGMAITLKDFGITDVIILEKGTVGHSFKHWPKSTLTITPSFTSNGFGMPDMNAISMDTSPAFTFNEEHISGETYAEYLQVVANHYELNIFENTVVTNISVDDAFYTIATTTETYHADYIFVATGDYNFPKKPFKYGIHYSEIEDFDNFNKGQYVVIGGNESGFDAAYQLAKNGSDIALYTSTTGLNDPDADPSVRLSPYTRQRLGNVIKQGARIEMNVHYTVKDIDFNNGQYHISFDSGQSVHTPHEPILATGFDATKNPIVQQLFVTTNQDIKLTTHDESTRYPNIFMIGATVENDNAKLCYIYKFRARFAVLAHLLTQREGLPAKQEVIENYQKNQMYLDDYSCCEVSCTC

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP029629_5	5.3\|1967192\|33\|NZ_CP029629\|CRISPRCasFinder	1967192-1967224	33	NZ_CP029629.1	809364-809396	0	1.0
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP029629.1	142650-142678	1	0.966
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP029629.1	265894-265922	1	0.966
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP029629.1	390294-390322	1	0.966
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP029629.1	390349-390377	1	0.966
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP029629.1	809371-809399	1	0.966
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP029629.1	1275771-1275799	1	0.966
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP029629.1	1320620-1320648	1	0.966
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP029629.1	1408346-1408374	1	0.966
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP029629.1	1563551-1563579	1	0.966
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP029629.1	1563609-1563637	1	0.966
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP029629.1	1647445-1647473	1	0.966
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP029629.1	1651414-1651442	1	0.966
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP029629.1	1874887-1874915	1	0.966
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP029629.1	1923999-1924027	1	0.966
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP029629.1	1972633-1972661	1	0.966
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP029629.1	2327626-2327654	1	0.966
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP029629.1	2361848-2361876	1	0.966
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP029629.1	2650369-2650397	1	0.966
NZ_CP029629_4	4.1\|1924052\|34\|NZ_CP029629\|CRISPRCasFinder	1924052-1924085	34	NZ_CP029629.1	1320732-1320765	1	0.971
NZ_CP029629_5	5.1\|1967189\|25\|NZ_CP029629\|PILER-CR	1967189-1967213	25	NZ_CP029629.1	809328-809352	1	0.96
NZ_CP029629_5	5.1\|1967189\|25\|NZ_CP029629\|PILER-CR	1967189-1967213	25	NZ_CP029629.1	1136340-1136364	1	0.96
NZ_CP029629_5	5.1\|1967189\|25\|NZ_CP029629\|PILER-CR	1967189-1967213	25	NZ_CP029629.1	1275645-1275669	1	0.96
NZ_CP029629_5	5.1\|1967189\|25\|NZ_CP029629\|PILER-CR	1967189-1967213	25	NZ_CP029629.1	1275701-1275725	1	0.96
NZ_CP029629_5	5.1\|1967189\|25\|NZ_CP029629\|PILER-CR	1967189-1967213	25	NZ_CP029629.1	1320752-1320776	1	0.96
NZ_CP029629_5	5.1\|1967189\|25\|NZ_CP029629\|PILER-CR	1967189-1967213	25	NZ_CP029629.1	1408218-1408242	1	0.96
NZ_CP029629_5	5.1\|1967189\|25\|NZ_CP029629\|PILER-CR	1967189-1967213	25	NZ_CP029629.1	2013751-2013775	1	0.96
NZ_CP029629_5	5.1\|1967189\|25\|NZ_CP029629\|PILER-CR	1967189-1967213	25	NZ_CP029629.1	2361978-2362002	1	0.96
NZ_CP029629_5	5.1\|1967189\|25\|NZ_CP029629\|PILER-CR	1967189-1967213	25	NZ_CP029629.1	2598361-2598385	1	0.96
NZ_CP029629_5	5.1\|1967189\|25\|NZ_CP029629\|PILER-CR	1967189-1967213	25	NZ_CP029629.1	2766778-2766802	1	0.96
NZ_CP029629_8	8.1\|2650422\|34\|NZ_CP029629\|CRISPRCasFinder	2650422-2650455	34	NZ_CP029629.1	1320732-1320765	1	0.971
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP029629.1	265839-265867	2	0.931
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP029629.1	2517651-2517679	2	0.931
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP029629.1	2598487-2598515	2	0.931
NZ_CP029629_4	4.1\|1924052\|34\|NZ_CP029629\|CRISPRCasFinder	1924052-1924085	34	NZ_CP029629.1	1563493-1563526	2	0.941
NZ_CP029629_8	8.1\|2650422\|34\|NZ_CP029629\|CRISPRCasFinder	2650422-2650455	34	NZ_CP029629.1	1563493-1563526	2	0.941

1. spacer 5.3|1967192|33|NZ_CP029629|CRISPRCasFinder matches to position: 809364-809396, mismatch: 0, identity: 1.0

ggtgtgggccccaacacagagaatttcgaaaag	CRISPR spacer
ggtgtgggccccaacacagagaatttcgaaaag	Protospacer
*********************************

2. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to position: 142650-142678, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

3. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to position: 265894-265922, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

4. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to position: 390294-390322, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctttgttggggc	Protospacer
******************* *********

5. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to position: 390349-390377, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctttgttggggc	Protospacer
******************* *********

6. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to position: 809371-809399, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

7. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to position: 1275771-1275799, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

8. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to position: 1320620-1320648, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

9. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to position: 1408346-1408374, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

10. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to position: 1563551-1563579, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcatttcgaaattctctatgttggggc	Protospacer
**** ************************

11. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to position: 1563609-1563637, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

12. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to position: 1647445-1647473, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttctttttgaaattctctatgttggggc	Protospacer
********.********************

13. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to position: 1651414-1651442, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

14. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to position: 1874887-1874915, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

15. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to position: 1923999-1924027, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

16. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to position: 1972633-1972661, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

17. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to position: 2327626-2327654, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttctttttgaaattctctatgttggggc	Protospacer
********.********************

18. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to position: 2361848-2361876, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

19. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to position: 2650369-2650397, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

20. spacer 4.1|1924052|34|NZ_CP029629|CRISPRCasFinder matches to position: 1320732-1320765, mismatch: 1, identity: 0.971

atgggccccaacaaagagaaattggattctcaat	CRISPR spacer
atgggccccaacaaagagaaattggattcccaat	Protospacer
*****************************.****

21. spacer 5.1|1967189|25|NZ_CP029629|PILER-CR matches to position: 809328-809352, mismatch: 1, identity: 0.96

attggatttccaatttctacagaca	CRISPR spacer
attggattcccaatttctacagaca	Protospacer
********.****************

22. spacer 5.1|1967189|25|NZ_CP029629|PILER-CR matches to position: 1136340-1136364, mismatch: 1, identity: 0.96

attggatttccaatttctacagaca	CRISPR spacer
attggattgccaatttctacagaca	Protospacer
******** ****************

23. spacer 5.1|1967189|25|NZ_CP029629|PILER-CR matches to position: 1275645-1275669, mismatch: 1, identity: 0.96

attggatttccaatttctacagaca	CRISPR spacer
attggattcccaatttctacagaca	Protospacer
********.****************

24. spacer 5.1|1967189|25|NZ_CP029629|PILER-CR matches to position: 1275701-1275725, mismatch: 1, identity: 0.96

attggatttccaatttctacagaca	CRISPR spacer
attggattcccaatttctacagaca	Protospacer
********.****************

25. spacer 5.1|1967189|25|NZ_CP029629|PILER-CR matches to position: 1320752-1320776, mismatch: 1, identity: 0.96

attggatttccaatttctacagaca	CRISPR spacer
attggattcccaatttctacagaca	Protospacer
********.****************

26. spacer 5.1|1967189|25|NZ_CP029629|PILER-CR matches to position: 1408218-1408242, mismatch: 1, identity: 0.96

attggatttccaatttctacagaca	CRISPR spacer
attggattcccaatttctacagaca	Protospacer
********.****************

27. spacer 5.1|1967189|25|NZ_CP029629|PILER-CR matches to position: 2013751-2013775, mismatch: 1, identity: 0.96

attggatttccaatttctacagaca	CRISPR spacer
attggattcccaatttctacagaca	Protospacer
********.****************

28. spacer 5.1|1967189|25|NZ_CP029629|PILER-CR matches to position: 2361978-2362002, mismatch: 1, identity: 0.96

attggatttccaatttctacagaca	CRISPR spacer
attggattcccaatttctacagaca	Protospacer
********.****************

29. spacer 5.1|1967189|25|NZ_CP029629|PILER-CR matches to position: 2598361-2598385, mismatch: 1, identity: 0.96

attggatttccaatttctacagaca	CRISPR spacer
attggattcccaatttctacagaca	Protospacer
********.****************

30. spacer 5.1|1967189|25|NZ_CP029629|PILER-CR matches to position: 2766778-2766802, mismatch: 1, identity: 0.96

attggatttccaatttctacagaca	CRISPR spacer
attggattcccaatttctacagaca	Protospacer
********.****************

31. spacer 8.1|2650422|34|NZ_CP029629|CRISPRCasFinder matches to position: 1320732-1320765, mismatch: 1, identity: 0.971

atgggccccaacacagagaaattggattcccaat	CRISPR spacer
atgggccccaacaaagagaaattggattcccaat	Protospacer
************* ********************

32. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to position: 265839-265867, mismatch: 2, identity: 0.931

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctttgtgttggggc	Protospacer
*****************.*.*********

33. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to position: 2517651-2517679, mismatch: 2, identity: 0.931

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttctttttgaaattctctgtgttggggc	Protospacer
********.**********.*********

34. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to position: 2598487-2598515, mismatch: 2, identity: 0.931

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcatttcgaaattctctgtgttggggc	Protospacer
**** **************.*********

35. spacer 4.1|1924052|34|NZ_CP029629|CRISPRCasFinder matches to position: 1563493-1563526, mismatch: 2, identity: 0.941

atgggccccaacaaagagaaattggattctcaat	CRISPR spacer
atgggccccaacaaagagaagttggattcccaat	Protospacer
********************.********.****

36. spacer 8.1|2650422|34|NZ_CP029629|CRISPRCasFinder matches to position: 1563493-1563526, mismatch: 2, identity: 0.941

atgggccccaacacagagaaattggattcccaat	CRISPR spacer
atgggccccaacaaagagaagttggattcccaat	Protospacer
************* ******.*************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP029629_5	5.1\|1967189\|25\|NZ_CP029629\|PILER-CR	1967189-1967213	25	MN693923	Marine virus AFVG_250M958, complete genome	22918-22942	4	0.84
NZ_CP029629_5	5.1\|1967189\|25\|NZ_CP029629\|PILER-CR	1967189-1967213	25	MN694427	Marine virus AFVG_250M959, complete genome	30328-30352	4	0.84
NZ_CP029629_5	5.1\|1967189\|25\|NZ_CP029629\|PILER-CR	1967189-1967213	25	AP014226	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C9-MedDCM-OCT-S44-C3, * SEQUENCING IN PROGRESS *	28488-28512	5	0.8
NZ_CP029629_5	5.1\|1967189\|25\|NZ_CP029629\|PILER-CR	1967189-1967213	25	AP014225	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C9-MedDCM-OCT-S41-C89, * SEQUENCING IN PROGRESS *	24653-24677	5	0.8
NZ_CP029629_2	2.1\|1016025\|29\|NZ_CP029629\|CRISPRCasFinder	1016025-1016053	29	NZ_CP018781	Ochrobactrum pituitosum strain AA2 plasmid pOAAA2, complete sequence	148987-149015	7	0.759

1. spacer 5.1|1967189|25|NZ_CP029629|PILER-CR matches to MN693923 (Marine virus AFVG_250M958, complete genome) position: , mismatch: 4, identity: 0.84

attggatttccaatttctacagaca	CRISPR spacer
ctttgatttccaatttctacatacc	Protospacer
 ** ***************** **

2. spacer 5.1|1967189|25|NZ_CP029629|PILER-CR matches to MN694427 (Marine virus AFVG_250M959, complete genome) position: , mismatch: 4, identity: 0.84

attggatttccaatttctacagaca	CRISPR spacer
ctttgatttccaatttctacatacc	Protospacer
 ** ***************** **

3. spacer 5.1|1967189|25|NZ_CP029629|PILER-CR matches to AP014226 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C9-MedDCM-OCT-S44-C3, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 5, identity: 0.8

attggatttccaatttctacagaca	CRISPR spacer
gttggatttccattttctacagttc	Protospacer
.*********** ********* .

4. spacer 5.1|1967189|25|NZ_CP029629|PILER-CR matches to AP014225 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C9-MedDCM-OCT-S41-C89, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 5, identity: 0.8

attggatttccaatttctacagaca	CRISPR spacer
gttggatttccattttctacagttc	Protospacer
.*********** ********* .

5. spacer 2.1|1016025|29|NZ_CP029629|CRISPRCasFinder matches to NZ_CP018781 (Ochrobactrum pituitosum strain AA2 plasmid pOAAA2, complete sequence) position: , mismatch: 7, identity: 0.759

tttcttttcgaaattctctatgttggggc	CRISPR spacer
accatcttcgtaatgctctatgttggggc	Protospacer
 .. *.**** *** **************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

325275 : 368878

Staphylococcus_phage(70.97%)

plate,protease,terminase,integrase,capsid,head,tail,holin,portal

attL 325165:325182|attR 369612:369629

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
325165:325182	attL	NA	NA	NA	NA
WP_000264745.1\|325275_326481_-\|integrase	site-specific integrase	Q4ZBP1	Staphylococcus_phage	1.9e-221	99.8
WP_000191466.1\|326606_327221_+	hypothetical protein	A0A2I6PEZ0	Staphylococcus_phage	6.7e-106	100.0
WP_074370993.1\|327217_327364_-	hypothetical protein	A0A2I6PEK8	Staphylococcus_phage	1.7e-15	93.8
WP_000449655.1\|327453_327849_-	hypothetical protein	A0A2I6PEJ7	Staphylococcus_phage	3.8e-70	100.0
WP_000755718.1\|327877_328312_-	hypothetical protein	A0A2I6PEM0	Staphylococcus_phage	1.2e-24	100.0
WP_000525000.1\|328329_328791_-	hypothetical protein	A0A2I6PEK4	Staphylococcus_phage	1.3e-85	99.3
WP_000429766.1\|328803_329133_-	helix-turn-helix transcriptional regulator	A0A2I6PEN2	Staphylococcus_phage	3.2e-54	100.0
WP_001115060.1\|329293_329485_+	helix-turn-helix transcriptional regulator	A0A2I6PEL6	Staphylococcus_phage	2.3e-28	100.0
WP_001001356.1\|329568_329745_+	hypothetical protein	A0A2I6PEL1	Staphylococcus_phage	8.8e-27	100.0
WP_001548903.1\|329741_329981_-	hypothetical protein	A0A2I6PE22	Staphylococcus_phage	6.7e-38	100.0
WP_001036299.1\|330027_330243_+	hypothetical protein	A0A2I6PEK7	Staphylococcus_phage	1.0e-32	100.0
WP_001124198.1\|330267_330531_+	helix-turn-helix domain-containing protein	A0A2I6PEL8	Staphylococcus_phage	2.5e-46	100.0
WP_001285948.1\|330543_330705_+	DUF1270 domain-containing protein	A9CR58	Staphylococcus_phage	1.1e-20	98.1
WP_000174994.1\|330783_331107_+	hypothetical protein	A0A2I6PF12	Staphylococcus_phage	5.9e-53	100.0
WP_000985976.1\|331121_331484_+	hypothetical protein	A0A2I6PF03	Staphylococcus_phage	4.9e-56	100.0
WP_031776056.1\|331480_332647_+	DUF2800 domain-containing protein	A7TWG4	Staphylococcus_phage	2.7e-220	99.5
WP_000647288.1\|332673_333228_+	DUF2815 family protein	M9QRS1	Staphylococcus_phage	1.4e-99	100.0
WP_110161718.1\|333296_335249_+	DNA polymerase	B7T0G8	Staphylococcus_virus	0.0e+00	98.2
WP_001164628.1\|335261_335447_+	DUF3113 family protein	A0A2I6PEM8	Staphylococcus_phage	2.1e-26	98.4
WP_070008564.1\|335446_335848_+	PVL family protein	B7T0H0	Staphylococcus_virus	1.2e-68	100.0
WP_015994745.1\|335847_336105_+	DUF3310 domain-containing protein	B7T0H1	Staphylococcus_virus	7.5e-43	100.0
WP_015994746.1\|336107_336308_+	hypothetical protein	B7T0H2	Staphylococcus_virus	3.7e-29	100.0
WP_015994747.1\|336304_336994_+	N-6 DNA methylase	B7T0H3	Staphylococcus_virus	6.1e-132	100.0
WP_015994748.1\|337007_337214_+	hypothetical protein	B7T0H4	Staphylococcus_virus	7.8e-35	100.0
WP_015994749.1\|337216_337645_+	hypothetical protein	B7T0H5	Staphylococcus_virus	1.0e-73	100.0
WP_000983951.1\|337641_337836_+	hypothetical protein	B7T0H6	Staphylococcus_virus	1.1e-27	100.0
WP_110161654.1\|337832_338117_+	hypothetical protein	Q9G014	Staphylococcus_virus	2.2e-43	94.7
WP_015994751.1\|338109_338358_+	DUF1024 family protein	B7T0H8	Staphylococcus_virus	4.1e-38	100.0
WP_015994752.1\|338350_338911_+	dUTP diphosphatase	B7T0H9	Staphylococcus_virus	1.8e-102	100.0
WP_029265348.1\|338947_339148_+	hypothetical protein	NA	NA	NA	NA
WP_015994753.1\|339147_339351_+	DUF1381 domain-containing protein	B7T0I0	Staphylococcus_virus	3.5e-19	100.0
WP_015994754.1\|339347_339500_+	hypothetical protein	B7T0I1	Staphylococcus_virus	8.9e-20	100.0
WP_000265258.1\|339567_339768_+	DUF1514 family protein	A0A2I6PF41	Staphylococcus_phage	2.9e-26	100.0
WP_069990205.1\|339819_342267_+	virulence-associated E family protein	B7T0I3	Staphylococcus_virus	0.0e+00	99.9
WP_015978074.1\|342369_342474_-	hypothetical protein	A0A2I6PDP6	Staphylococcus_phage	2.7e-12	100.0
WP_015978062.1\|342607_342898_+	VRR-NUC domain-containing protein	B7T0I4	Staphylococcus_virus	4.9e-51	100.0
WP_110161655.1\|342878_344246_+	DEAD/DEAH box helicase	B7T0I5	Staphylococcus_virus	3.5e-264	99.6
WP_000513702.1\|344258_344696_+	transcriptional regulator	B7T0I6	Staphylococcus_virus	6.1e-77	100.0
WP_015994756.1\|344852_345167_+	HNH endonuclease	A0A0K1LL59	Staphylococcus_phage	4.2e-56	100.0
WP_000778933.1\|345293_345599_+\|terminase	P27 family phage terminase small subunit	A0A2I6PEQ6	Staphylococcus_phage	2.9e-49	100.0
WP_000153551.1\|345588_347280_+\|terminase	terminase large subunit	A0A2I6PE99	Staphylococcus_phage	0.0e+00	99.8
WP_001100669.1\|347284_348523_+\|portal	phage portal protein	A0A2K9VBP0	Staphylococcus_phage	6.9e-235	100.0
WP_000061866.1\|348506_349280_+\|protease	Clp protease ClpP	A0A2I6PEQ7	Staphylococcus_phage	2.4e-137	100.0
WP_031776039.1\|349291_350455_+\|capsid	phage major capsid protein	A0A0K1LKB5	Staphylococcus_phage	2.7e-217	100.0
WP_000050973.1\|350523_350802_+\|head,tail	phage gp6-like head-tail connector protein	A0A2I6PEQ1	Staphylococcus_phage	2.1e-46	100.0
WP_016187452.1\|350813_351146_+	hypothetical protein	M9QX19	Staphylococcus_phage	1.1e-57	100.0
WP_061730450.1\|351142_351544_+	hypothetical protein	A0A0K1LL98	Staphylococcus_phage	6.8e-67	99.2
WP_001023808.1\|351544_351940_+	DUF3168 domain-containing protein	A0A0K1LKC0	Staphylococcus_phage	5.1e-67	100.0
WP_000807536.1\|351974_352616_+\|tail	tail protein	A0A2I6PEP6	Staphylococcus_phage	5.9e-121	100.0
WP_110161656.1\|352707_353163_+	Ig domain-containing protein	A0A2I6PER6	Staphylococcus_phage	1.7e-77	99.3
WP_000589167.1\|353220_353571_+	hypothetical protein	A0A2I6PEQ2	Staphylococcus_phage	1.1e-55	100.0
WP_000438833.1\|353612_353771_+	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
WP_110161657.1\|353784_359985_+\|tail	phage tail tape measure protein	M9QQM6	Staphylococcus_phage	0.0e+00	99.2
WP_031865253.1\|359984_360809_+\|tail	phage tail family protein	A0A2I6PEE1	Staphylococcus_phage	5.4e-159	100.0
WP_000384462.1\|360817_362401_+\|tail	phage tail protein	Q8SDP1	Staphylococcus_virus	7.1e-309	100.0
WP_000179860.1\|362400_362691_+	hypothetical protein	A0A2I6PF46	Staphylococcus_phage	2.1e-49	100.0
WP_031774595.1\|362706_364617_+	minor structural protein	A0A2I6PF35	Staphylococcus_phage	0.0e+00	99.7
WP_103213504.1\|364616_366083_+\|plate	phage baseplate upper protein	A0A2I6PES7	Staphylococcus_phage	6.4e-272	99.6
WP_001166599.1\|366082_366472_+	DUF2977 domain-containing protein	A0A2I6PER1	Staphylococcus_phage	2.2e-62	100.0
WP_000916020.1\|366464_366629_+	XkdX family protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
WP_000466784.1\|366674_366974_+	DUF2951 domain-containing protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
WP_000339146.1\|367109_367412_+\|holin	phage holin	A0A2I6PET6	Staphylococcus_phage	7.0e-48	100.0
WP_000930258.1\|367423_368878_+	N-acetylmuramoyl-L-alanine amidase	A0A0N6WMR3	Staphylococcus_phage	3.0e-290	100.0
369612:369629	attR	NA	NA	NA	NA

DBSCAN-SWA_2

681224 : 733126

Staphylococcus_phage(50.0%)

coat,protease,terminase,integrase,tRNA,transposase

attL 719787:719806|attR 736156:736175

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001808146.1\|681224_682544_-\|transposase	ISL3-like element IS1181 family transposase	NA	NA	NA	NA
WP_000688533.1\|682945_683362_+	hypothetical protein	NA	NA	NA	NA
WP_000216855.1\|683438_684707_-	threonine ammonia-lyase IlvA	NA	NA	NA	NA
WP_000718953.1\|684721_685294_-	3-isopropylmalate dehydratase small subunit	NA	NA	NA	NA
WP_000531820.1\|685294_686665_-	3-isopropylmalate dehydratase large subunit	NA	NA	NA	NA
WP_000221946.1\|686678_687725_-	3-isopropylmalate dehydrogenase	NA	NA	NA	NA
WP_070002065.1\|687727_689257_-	2-isopropylmalate synthase	E5EQ69	Micromonas_sp._RCC1109_virus	5.5e-08	27.8
WP_159426937.1\|689286_690306_-	ketol-acid reductoisomerase	NA	NA	NA	NA
WP_000196911.1\|690427_690682_-	ACT domain-containing protein	NA	NA	NA	NA
WP_000047820.1\|690681_692451_-	biosynthetic-type acetolactate synthase large subunit	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	5.3e-63	30.1
WP_001255780.1\|692478_694167_-	dihydroxy-acid dehydratase	NA	NA	NA	NA
WP_001789600.1\|694484_694640_-	hypothetical protein	NA	NA	NA	NA
WP_000590797.1\|694677_695139_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_001086742.1\|695119_695782_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_000372758.1\|695754_696219_+	ribosomal protein S18-alanine N-acetyltransferase	NA	NA	NA	NA
WP_000159053.1\|696211_697237_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	5.8e-62	40.6
WP_000106329.1\|697338_698949_-	MutS family DNA mismatch repair protein	A0A0N9R0S5	Chrysochromulina_ericina_virus	3.3e-19	26.9
WP_001792272.1\|699629_699758_+	hypothetical protein	NA	NA	NA	NA
WP_000602069.1\|699902_701831_-	ABC-F type ribosomal protection protein	A0A2K9L0W2	Tupanvirus	2.4e-53	30.4
WP_001283612.1\|702083_702719_+	redox-sensing transcriptional repressor Rex	NA	NA	NA	NA
WP_000266883.1\|703022_704102_+	YeeE/YedE family protein	NA	NA	NA	NA
WP_000581077.1\|704161_704386_+	sulfurtransferase TusA family protein	NA	NA	NA	NA
WP_110161666.1\|704592_705843_+	ammonium transporter	H8ZJB2	Ostreococcus_tauri_virus	7.6e-40	31.2
WP_000790324.1\|706025_706976_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_000141426.1\|707124_708609_+	sucrose-6-phosphate hydrolase	S6ATV4	Bacillus_phage	4.0e-19	25.6
WP_001253302.1\|708605_709565_+	carbohydrate kinase	NA	NA	NA	NA
WP_000688498.1\|709933_710650_-	response regulator transcription factor	A0A2H4J4Z6	uncultured_Caudovirales_phage	3.0e-25	32.6
WP_031929881.1\|710668_711961_-	GHKL domain-containing protein	NA	NA	NA	NA
WP_001093929.1\|711985_712126_-	cyclic lactone autoinducer peptide	NA	NA	NA	NA
WP_001105707.1\|712122_712692_-	accessory gene regulator AgrB	NA	NA	NA	NA
WP_001549197.1\|712927_713062_+	delta-lysin family phenol-soluble modulin	NA	NA	NA	NA
WP_000867940.1\|713657_714443_-	carbon-nitrogen family hydrolase	NA	NA	NA	NA
WP_000522384.1\|714803_715430_-	nitroreductase family protein	NA	NA	NA	NA
WP_000120323.1\|715625_716885_+	hypothetical protein	NA	NA	NA	NA
WP_000197635.1\|716909_717653_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000917289.1\|717827_718112_+	co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2
WP_000240645.1\|718187_719804_+	chaperonin GroEL	A0A240F779	uncultured_virus	3.4e-157	54.7
719787:719806	attL	NA	NA	NA	NA
WP_070046546.1\|719872_721045_-\|integrase	tyrosine-type recombinase/integrase	A0A1W6JQD3	Staphylococcus_phage	5.9e-220	98.5
WP_000620856.1\|721058_721733_-	helix-turn-helix transcriptional regulator	A0A2H4JGT9	uncultured_Caudovirales_phage	4.5e-39	45.3
WP_000153640.1\|721905_722124_+	helix-turn-helix transcriptional regulator	A0A2H4JB11	uncultured_Caudovirales_phage	1.3e-19	66.7
WP_000481967.1\|722128_722446_+	helix-turn-helix domain-containing protein	A0A1W6JQE0	Staphylococcus_phage	9.2e-51	98.1
WP_000784889.1\|722442_722598_+	hypothetical protein	NA	NA	NA	NA
WP_001231374.1\|722582_722786_+	hypothetical protein	A0A1W6JQF4	Staphylococcus_phage	7.5e-30	97.0
WP_000695071.1\|722787_723171_+	hypothetical protein	A0A1W6JQI7	Staphylococcus_phage	2.2e-62	96.9
WP_001103965.1\|723171_723498_+	DUF1474 family protein	Q4ZE75	Staphylococcus_phage	1.8e-54	98.1
WP_001002725.1\|723562_724432_+	primase C-terminal domain-containing protein	Q4ZE74	Staphylococcus_phage	5.0e-163	95.5
WP_070001967.1\|724445_726155_+	DUF927 domain-containing protein	Q4ZE73	Staphylococcus_phage	0.0e+00	98.8
WP_000356933.1\|726466_726847_+	hypothetical protein	Q4ZE71	Staphylococcus_phage	2.6e-68	97.6
WP_001019789.1\|726843_727485_+	hypothetical protein	Q4ZE67	Staphylococcus_phage	3.8e-104	88.7
WP_001190614.1\|727933_728275_+	hypothetical protein	Q4ZE66	Staphylococcus_phage	2.9e-58	100.0
WP_000846281.1\|728286_728865_+	hypothetical protein	A0A2H4JBG0	uncultured_Caudovirales_phage	3.7e-29	38.9
WP_000448776.1\|728882_729101_+	hypothetical protein	NA	NA	NA	NA
WP_000771377.1\|729151_729679_+\|coat	spore coat protein	Q4ZE87	Staphylococcus_phage	3.2e-88	96.6
WP_078063999.1\|729810_730023_+	pathogenicity island family protein	Q4ZE86	Staphylococcus_phage	1.1e-28	88.6
WP_001293070.1\|730019_730589_+\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	5.1e-100	96.8
WP_001245081.1\|730772_732242_+	hypothetical protein	NA	NA	NA	NA
WP_000879843.1\|732442_733126_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
736156:736175	attR	NA	NA	NA	NA

DBSCAN-SWA_3

849269 : 899662

Staphylococcus_phage(85.71%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000379980.1\|849269_850397_+\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_000181394.1\|850401_850872_+\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
WP_001251224.1\|851030_851630_+	glucosamine-6-phosphate isomerase	NA	NA	NA	NA
WP_000031108.1\|851654_851807_+	hypothetical protein	NA	NA	NA	NA
WP_000901023.1\|852350_852746_+	hypothetical protein	NA	NA	NA	NA
WP_000116229.1\|852941_854327_+	class II fumarate hydratase	NA	NA	NA	NA
WP_000669376.1\|854778_855600_-	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_000437970.1\|855762_856875_+	GAF domain-containing sensor histidine kinase	NA	NA	NA	NA
WP_001045133.1\|856896_857520_+	response regulator transcription factor	NA	NA	NA	NA
WP_000375864.1\|857875_858340_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000992524.1\|858518_859643_+	DUF445 domain-containing protein	NA	NA	NA	NA
WP_000290301.1\|859711_860056_+	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	7.5e-06	29.7
WP_031797668.1\|860704_860803_+	hypothetical protein	NA	NA	NA	NA
WP_000238223.1\|861093_862290_+	exonuclease SbcCD subunit D	NA	NA	NA	NA
WP_000584628.1\|862279_865216_+	AAA family ATPase	NA	NA	NA	NA
WP_001244180.1\|865212_866154_+	3'-5' exoribonuclease YhaM	NA	NA	NA	NA
WP_000782121.1\|866274_867237_-	foldase	NA	NA	NA	NA
WP_000477963.1\|867441_867999_-	DUF3267 domain-containing protein	NA	NA	NA	NA
WP_000648118.1\|868731_869097_-	YtxH domain-containing protein	NA	NA	NA	NA
WP_000004981.1\|869238_869661_-	HIT family protein	NA	NA	NA	NA
WP_000216874.1\|869794_870535_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.2e-24	29.8
WP_001245767.1\|870527_871751_+	ABC transporter permease	NA	NA	NA	NA
WP_000737976.1\|871874_872378_-	signal transduction protein TRAP	NA	NA	NA	NA
WP_001790154.1\|872540_872651_+	hypothetical protein	NA	NA	NA	NA
WP_000233526.1\|872640_873678_+	uroporphyrinogen decarboxylase	NA	NA	NA	NA
WP_000162885.1\|873735_874659_+	ferrochelatase	NA	NA	NA	NA
WP_000167550.1\|874682_876083_+	protoporphyrinogen oxidase	NA	NA	NA	NA
WP_000132890.1\|876405_876960_+	serine hydrolase family protein	NA	NA	NA	NA
WP_001253316.1\|879358_879853_-	hypothetical protein	NA	NA	NA	NA
WP_000848323.1\|880250_881027_-	DUF1828 domain-containing protein	NA	NA	NA	NA
WP_000617705.1\|881047_881284_-	hypothetical protein	NA	NA	NA	NA
WP_000711492.1\|881870_883217_-	DUF4041 domain-containing protein	M1NRY5	Streptococcus_phage	5.7e-65	50.8
WP_069993660.1\|883383_883980_-	hypothetical protein	NA	NA	NA	NA
WP_000041511.1\|884448_884694_-	hypothetical protein	NA	NA	NA	NA
WP_000878802.1\|885601_886522_+	bi-component leukocidin LukED subunit E	A0A2H4PQI5	Staphylococcus_phage	2.3e-174	100.0
WP_000782446.1\|886523_887507_+	bi-component leukocidin LukED subunit D	A0A2H4PQH7	Staphylococcus_phage	2.3e-185	99.1
WP_000543856.1\|887876_888668_-	DUF1828 domain-containing protein	NA	NA	NA	NA
WP_000550252.1\|888672_889146_-	hypothetical protein	NA	NA	NA	NA
WP_001092776.1\|890093_890663_-	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	2.6e-51	62.6
WP_001039433.1\|891626_892334_+\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	7.7e-130	99.6
WP_069993661.1\|892458_893181_+\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	2.4e-131	99.6
WP_001038872.1\|893238_893958_+\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	1.3e-129	98.7
WP_001038706.1\|894078_894798_+\|protease	serine protease SplD	A0A2H4PQP9	Staphylococcus_phage	5.1e-129	99.2
WP_011447030.1\|894746_894854_-	hypothetical protein	NA	NA	NA	NA
WP_070002063.1\|894955_895672_+\|protease	serine protease SplE	A0A2H4PQN5	Staphylococcus_phage	7.0e-131	98.7
WP_001038690.1\|895822_896542_+\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.9e-131	99.6
WP_001791797.1\|896606_896741_+	hypothetical protein	NA	NA	NA	NA
WP_174202462.1\|896904_898461_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.8e-286	98.8
WP_000072589.1\|898453_899662_+	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	9.3e-35	31.5

DBSCAN-SWA_4

908856 : 954217

Staphylococcus_phage(94.29%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000864143.1\|908856_909414_+	ImmA/IrrE family metallo-endopeptidase	A0A2H4PQN8	Staphylococcus_phage	2.7e-77	96.2
WP_000414214.1\|909610_910183_-	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	1.1e-25	96.6
WP_000627537.1\|910283_910625_-	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	3.0e-55	95.6
WP_000669027.1\|910665_911292_-	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	5.3e-90	93.8
WP_000070655.1\|911367_912363_-	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	6.2e-77	98.8
WP_001795535.1\|912443_913094_-	excalibur calcium-binding domain-containing protein	A0A2H4PQM8	Staphylococcus_phage	2.7e-44	88.4
WP_069993433.1\|914011_915490_+	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.4e-282	97.2
WP_000778525.1\|915494_916496_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	2.2e-186	97.9
WP_000718107.1\|916492_916750_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000672014.1\|916815_917289_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	4.7e-83	98.1
WP_001834463.1\|917293_918040_+	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	1.4e-142	98.8
WP_000109906.1\|918417_920010_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
WP_000933822.1\|920381_921575_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_000366166.1\|921699_922608_+	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	1.3e-137	99.7
WP_000453314.1\|922819_923653_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	5.4e-159	100.0
WP_000623478.1\|924035_924389_-	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	2.6e-22	100.0
WP_001200542.1\|924385_924751_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
WP_000091445.1\|925006_925309_-	hypothetical protein	NA	NA	NA	NA
WP_001096494.1\|925568_926282_+	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_001168901.1\|926721_927357_-\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001030469.1\|927652_928096_+	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
WP_001153742.1\|928082_928526_-	competence protein ComK	NA	NA	NA	NA
WP_000671052.1\|928638_929109_-	RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	1.0e-82	99.4
WP_000384171.1\|929307_929532_+	hypothetical protein	NA	NA	NA	NA
WP_001032833.1\|929807_930662_+	glucosaminidase domain-containing protein	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000989122.1\|930748_932041_-	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	9.4e-227	99.3
WP_000221177.1\|932040_932355_-	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	9.8e-53	98.1
WP_001261668.1\|932877_934380_+	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	1.9e-29	98.6
WP_000077358.1\|934860_935904_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	5.3e-196	98.8
WP_000493892.1\|935910_936543_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.7e-112	99.5
WP_001159022.1\|936553_937735_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	6.6e-227	99.7
WP_001008551.1\|937747_938212_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
WP_001196354.1\|938333_939335_-	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
WP_001790712.1\|939446_939566_+	hypothetical protein	NA	NA	NA	NA
WP_000266096.1\|939568_940396_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_070046572.1\|940967_941369_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000764419.1\|941488_942052_-	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
WP_000526539.1\|942048_943002_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_001025061.1\|943111_944293_+	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	5.6e-218	100.0
WP_001808015.1\|944580_946998_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.3
WP_000836465.1\|947019_947331_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
WP_070046571.1\|947656_954217_+	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	1.6e-309	99.0

DBSCAN-SWA_5

1079555 : 1088598

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_070001834.1\|1079555_1080560_+	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1
WP_001019178.1\|1080561_1081587_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001112045.1\|1081609_1082749_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001160682.1\|1082767_1083028_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_000749795.1\|1083302_1085582_+	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_000594991.1\|1085784_1088058_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	5.2e-63	28.8
WP_000364542.1\|1088079_1088598_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5

DBSCAN-SWA_6

1156433 : 1164763

Caulobacter_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001217257.1\|1156433_1158251_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	7.9e-54	36.3
WP_001283055.1\|1158474_1159581_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_000624586.1\|1159711_1160389_+\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_110161674.1\|1160391_1161492_+	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
WP_001062187.1\|1161605_1162952_+	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
WP_000924220.1\|1162961_1163852_+	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	3.4e-26	36.0
WP_001213908.1\|1163977_1164763_+	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3

DBSCAN-SWA_7

1448437 : 1483636

Staphylococcus_phage(60.42%)

plate,terminase,head,capsid,tail,holin,integrase,portal

attL 1450472:1450531|attR 1483705:1483828

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001002340.1\|1448437_1448644_-	hypothetical protein	A0A2H4PQT0	Staphylococcus_phage	1.3e-13	59.7
WP_075111596.1\|1448940_1449159_-	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	6.4e-19	73.1
WP_001814546.1\|1449846_1450044_-	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	1.7e-10	50.0
1450472:1450531	attL	NA	NA	NA	NA
WP_001289724.1\|1451048_1451252_-	hypothetical protein	A0A2H4PQT0	Staphylococcus_phage	4.4e-14	61.8
WP_000006112.1\|1451899_1452085_-	hypothetical protein	A0A0F6N3H3	Staphylococcus_phage	1.9e-16	70.5
WP_000147562.1\|1452086_1452197_-	hypothetical protein	W5R8J7	Staphylococcus_phage	3.3e-08	83.3
WP_000889730.1\|1452266_1452395_-	hypothetical protein	A0A0F6N3H2	Staphylococcus_phage	7.5e-12	85.7
WP_001140242.1\|1452594_1453515_-	N-acetylmuramoyl-L-alanine amidase	A0A1W6JQL2	Staphylococcus_phage	7.0e-67	51.5
WP_000438657.1\|1453579_1453969_-\|holin	phage holin family protein	A0A1S6L1J2	Staphylococcus_phage	5.3e-16	38.2
WP_000013193.1\|1453981_1455379_-\|plate	phage baseplate upper protein	A0A1J0MFK8	Staphylococcus_phage	5.8e-105	44.7
WP_000700622.1\|1455397_1456411_-	SGNH/GDSL hydrolase family protein	A0A1J0MFI8	Staphylococcus_phage	1.1e-97	52.6
WP_000598513.1\|1456428_1458114_-\|tail	phage tail protein	Q4ZE19	Staphylococcus_virus	8.8e-108	46.3
WP_000350617.1\|1458122_1459058_-\|tail	phage tail family protein	A0A1J0MF79	Staphylococcus_phage	7.8e-98	55.9
WP_000016893.1\|1459072_1462243_-	hypothetical protein	Q4ZE24	Staphylococcus_virus	5.5e-95	54.7
WP_001808026.1\|1462254_1462608_-	hypothetical protein	Q4ZE25	Staphylococcus_virus	1.7e-37	72.3
WP_110161681.1\|1462658_1463003_-\|tail	phage tail protein	A0A1J0MFH0	Staphylococcus_phage	2.9e-34	58.0
WP_000276224.1\|1463064_1463664_-\|tail	phage major tail protein, TP901-1 family	H9A0N8	Staphylococcus_phage	7.4e-17	47.5
WP_000680037.1\|1463675_1464071_-	hypothetical protein	H9A0N7	Staphylococcus_phage	1.9e-21	42.3
WP_001198140.1\|1464080_1464431_-	HK97 gp10 family phage protein	H9A0N6	Staphylococcus_phage	9.3e-36	60.0
WP_001106897.1\|1464431_1464737_-	hypothetical protein	Q4ZE30	Staphylococcus_virus	6.4e-17	40.6
WP_001010139.1\|1464736_1465063_-\|head,tail	phage head-tail connector protein	Q4ZE31	Staphylococcus_virus	2.1e-26	56.4
WP_000104116.1\|1465078_1465552_-	Ig-like domain-containing protein	A0A2H4J9T3	uncultured_Caudovirales_phage	9.7e-12	31.6
WP_000200243.1\|1465629_1466541_-	hypothetical protein	Q4ZE33	Staphylococcus_virus	6.5e-97	59.7
WP_000429653.1\|1466559_1467138_-	DUF4355 domain-containing protein	Q4ZE34	Staphylococcus_virus	1.9e-09	50.8
WP_063644543.1\|1467104_1467233_-	hypothetical protein	NA	NA	NA	NA
WP_174202463.1\|1467432_1468962_-\|capsid	minor capsid protein	Q4ZE35	Staphylococcus_virus	2.1e-108	61.3
WP_000158568.1\|1468951_1470400_-\|portal	phage portal protein	Q4ZE36	Staphylococcus_virus	7.4e-196	69.4
WP_000207537.1\|1470412_1471687_-\|terminase	PBSX family phage terminase large subunit	Q4ZE37	Staphylococcus_virus	1.9e-195	76.4
WP_000090969.1\|1471673_1472102_-	helix-turn-helix domain-containing protein	A1EAE0	Streptococcus_phage	1.1e-25	45.1
WP_000653930.1\|1472254_1472743_-	hypothetical protein	R9TMH4	Paenibacillus_phage	4.3e-07	27.7
WP_000835355.1\|1473019_1473484_-	hypothetical protein	C9E2P0	Enterococcus_phage	3.2e-20	43.0
WP_025174970.1\|1473480_1473588_-	DUF1381 domain-containing protein	C8CH06	Staphylococcus_phage	3.2e-08	87.5
WP_000185176.1\|1473729_1474260_-	nucleotide pyrophosphohydrolase	A0A1P8VVP1	Streptococcus_phage	5.2e-22	38.2
WP_000860979.1\|1474252_1474564_-	hypothetical protein	NA	NA	NA	NA
WP_000714410.1\|1474563_1474728_-	hypothetical protein	A0A0E3T9L7	Staphylococcus_phage	1.1e-18	88.9
WP_042727657.1\|1474742_1475015_-	hypothetical protein	A0A223LIA9	Staphylococcus_phage	6.8e-18	58.1
WP_000929466.1\|1475033_1475936_-	DnaD domain protein	A0A1P8L6F0	Staphylococcus_phage	2.9e-49	52.0
WP_000702007.1\|1475948_1476497_-	hypothetical protein	A7TWM8	Staphylococcus_phage	1.1e-91	92.9
WP_000907597.1\|1476523_1477303_-	ATP-binding protein	A0A1W6JPW0	Staphylococcus_phage	2.3e-127	88.0
WP_110161682.1\|1477303_1477840_-	host-nuclease inhibitor Gam family protein	A0A0H3U480	Staphylococcus_phage	6.3e-76	81.9
WP_000786634.1\|1477844_1478111_-	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	3.0e-18	53.6
WP_000786993.1\|1478100_1478418_-	DUF2482 family protein	W5RAK4	Staphylococcus_phage	1.6e-39	80.6
WP_000072840.1\|1478504_1478666_-	DUF1270 family protein	R4IH12	Staphylococcus_phage	1.1e-12	69.8
WP_001157025.1\|1478764_1479448_-	phage repressor protein	A9CR56	Staphylococcus_phage	5.2e-107	85.6
WP_000800341.1\|1479508_1479715_+	hypothetical protein	A1BTY8	Staphylococcus_virus	3.3e-25	75.0
WP_000392387.1\|1479703_1479874_-	hypothetical protein	Q4ZDZ8	Staphylococcus_virus	2.4e-21	89.3
WP_000932238.1\|1480138_1480414_-	hypothetical protein	NA	NA	NA	NA
WP_110161683.1\|1480440_1480659_-	DUF739 family protein	A0A2I6PE94	Staphylococcus_phage	8.3e-19	62.5
WP_000664917.1\|1480826_1481219_+	helix-turn-helix domain-containing protein	A0A2I6PE55	Staphylococcus_phage	1.6e-28	53.6
WP_000554410.1\|1481365_1481749_+	hypothetical protein	NA	NA	NA	NA
WP_070001847.1\|1481760_1482456_+	Ltp family lipoprotein	A0A2H4J5B8	uncultured_Caudovirales_phage	3.6e-07	50.3
WP_001836882.1\|1482508_1483636_+\|integrase	site-specific integrase	A0A0C5AN64	Paenibacillus_phage	6.2e-33	31.4
1483705:1483828	attR	NA	NA	NA	NA

DBSCAN-SWA_8

1739859 : 1748332

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000238669.1\|1739859_1740426_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.1
WP_000030811.1\|1740428_1741457_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.4e-62	41.7
WP_070001857.1\|1741449_1742934_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.9e-45	31.7
WP_000032740.1\|1742912_1745102_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	3.5e-141	39.8
WP_000666806.1\|1745094_1745766_-	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_000848350.1\|1745767_1746031_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000174053.1\|1746030_1746735_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
WP_001010410.1\|1746738_1747863_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000861572.1\|1747849_1748332_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7

DBSCAN-SWA_9

1768376 : 1805180

Enterococcus_phage(20.0%)

protease,bacteriocin,integrase

attL 1763968:1763984|attR 1809563:1809579

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1763968:1763984	attL	NA	NA	NA	NA
WP_001089094.1\|1768376_1769558_+\|protease	cysteine protease staphopain B	NA	NA	NA	NA
WP_000284458.1\|1769595_1769925_+	staphostatin B	NA	NA	NA	NA
WP_000184945.1\|1770162_1770984_-	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
WP_000150197.1\|1770976_1771780_-	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase	NA	NA	NA	NA
WP_000526694.1\|1771766_1773440_-	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase	NA	NA	NA	NA
WP_000190622.1\|1773426_1774788_-	isochorismate synthase MenF	NA	NA	NA	NA
WP_000070966.1\|1774969_1775908_+	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
WP_000620949.1\|1775959_1776511_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000867357.1\|1776675_1776891_+	TM2 domain-containing protein	A0A060AN66	Enterococcus_phage	1.5e-07	49.1
WP_001790177.1\|1776954_1777086_+	hypothetical protein	NA	NA	NA	NA
WP_001081351.1\|1777131_1778091_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000766009.1\|1778578_1778935_+	DoxX family protein	NA	NA	NA	NA
WP_001792054.1\|1779023_1779161_-	poly(glycerol-phosphate) alpha-glucosyltransferase	NA	NA	NA	NA
WP_001795266.1\|1779301_1779592_+	hypothetical protein	NA	NA	NA	NA
WP_000571167.1\|1779679_1780321_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.7e-19	33.0
WP_110161688.1\|1780317_1780638_-	YxeA family protein	NA	NA	NA	NA
WP_000870827.1\|1780640_1782605_-\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA
WP_001797239.1\|1782648_1782921_-\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
WP_031763719.1\|1782930_1783032_-	hypothetical protein	NA	NA	NA	NA
WP_001033865.1\|1783946_1784549_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000214898.1\|1784563_1784740_-	YkvS family protein	NA	NA	NA	NA
WP_000668818.1\|1784936_1785923_+	lipoate--protein ligase	NA	NA	NA	NA
WP_000876826.1\|1786003_1786222_-	IDEAL domain-containing protein	NA	NA	NA	NA
WP_000287265.1\|1786431_1787001_+	competence protein ComK	NA	NA	NA	NA
WP_000414165.1\|1787487_1788999_-	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_000021865.1\|1789137_1790496_-	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_000928413.1\|1793055_1793859_-	TerC family protein	S5MAL1	Bacillus_phage	1.6e-30	40.5
WP_001049951.1\|1794160_1795723_-	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	1.7e-36	28.2
WP_001795833.1\|1795722_1795983_-	YueH family protein	NA	NA	NA	NA
WP_000340119.1\|1795963_1797448_-	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	NA	NA	NA	NA
WP_000258645.1\|1797880_1799056_+	diglucosyl diacylglycerol synthase	NA	NA	NA	NA
WP_070001853.1\|1799033_1800224_+	MFS transporter	NA	NA	NA	NA
WP_000600387.1\|1800336_1800846_-	2'-5' RNA ligase family protein	NA	NA	NA	NA
WP_001288675.1\|1801039_1801798_-	esterase family protein	NA	NA	NA	NA
WP_000706213.1\|1802001_1803114_+\|integrase	tyrosine-type recombinase/integrase	P97010	Streptococcus_pyogenes_phage	1.7e-11	31.6
WP_000026850.1\|1803116_1805180_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
1809563:1809579	attR	NA	NA	NA	NA

DBSCAN-SWA_10

2001080 : 2015810

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000616842.1\|2001080_2001842_-	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	8.5e-18	31.6
WP_001245577.1\|2001838_2002795_-	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_070046523.1\|2002781_2003753_-	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	2.1e-138	78.3
WP_000499195.1\|2003791_2003947_-	hypothetical protein	NA	NA	NA	NA
WP_000562498.1\|2004460_2005432_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000855505.1\|2005549_2007655_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000692521.1\|2007617_2008016_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_070046521.1\|2008816_2009683_+	DMT family transporter	NA	NA	NA	NA
WP_000930014.1\|2009702_2010203_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_000193751.1\|2010543_2012049_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_031797439.1\|2012126_2012228_-	hypothetical protein	NA	NA	NA	NA
WP_000429006.1\|2012317_2013235_+	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	2.1e-07	22.0
WP_000197275.1\|2013914_2014457_-	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000663025.1\|2014751_2015810_-	histidinol-phosphate transaminase	A0A0H3TLT9	Faustovirus	1.5e-20	27.3

DBSCAN-SWA_11

2027781 : 2035601

Pandoravirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001217794.1\|2027781_2028933_-	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	3.5e-23	36.1
WP_000604515.1\|2028916_2029510_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.2e-38	43.5
WP_000446724.1\|2029860_2030529_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000941336.1\|2030530_2030950_+	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_001062972.1\|2030953_2031667_+	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000637687.1\|2031765_2032350_+	hypothetical protein	NA	NA	NA	NA
WP_001093556.1\|2032629_2033070_+	DM13 domain-containing protein	NA	NA	NA	NA
WP_001037807.1\|2033411_2033885_+	DoxX family protein	NA	NA	NA	NA
WP_000149344.1\|2033859_2034546_+	response regulator transcription factor	NA	NA	NA	NA
WP_000244415.1\|2034545_2035601_+	two-component system sensor histidine kinase SaeS	A0A1V0SGX0	Hokovirus	3.6e-14	29.8

Anti-CRISPR protein detection

Acr_ID: NZ_CP029629.1|WP_031797439.1|2012126_2012228_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP029629.1|WP_031797439.1|2012126_2012228_-|hypothetical-protein

2012126_2012228_-

33 aa aa

2001080-2015810

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP029629_5	Unclear	5.1\|1967189\|25\|NZ_CP029629\|PILER-CR	1967189-1967213	25	2013775-2013751	1

1. spacer 5.1|1967189|25|NZ_CP029629|PILER-CR matches to NZ_CP029629 position: 2013775-2013751, mismatch: 1

attggatttccaatttctacagaca	CRISPR spacer
attggattcccaatttctacagaca	Protospacer
********.****************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP029629

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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