CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP020355	Staphylococcus aureus strain FORC59 plasmid pFORC59, complete sequence	0 crisprs	csa3	0	0	1	0
NZ_CP020354	Staphylococcus aureus strain FORC59 chromosome, complete genome	9 crisprs	cas3,DEDDh,DinG,csa3,WYL	11	3	7	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

350 : 11244

Streptococcus_phage(57.14%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002354485.1\|350_1037_+\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	2.0e-127	99.6
WP_012655884.1\|1349_2825_+	bifunctional aminoglycoside N-acetyltransferase AAC(6')-Ie/aminoglycoside O-phosphotransferase APH(2'')-Ia	A0A1X9I6C2	Streptococcus_phage	3.3e-284	99.8
WP_001814874.1\|3197_3281_+	23S rRNA methyltransferase attenuation leader peptide	NA	NA	NA	NA
WP_002292226.1\|3405_4143_+	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	1.4e-134	99.6
WP_000085863.1\|4147_4279_+	hypothetical protein	E4ZFP9	Streptococcus_phage	1.7e-14	93.0
WP_000576156.1\|4497_5052_+	recombinase family protein	A0A0F7LA37	Escherichia_phage	2.3e-36	52.1
WP_001240982.1\|5055_7974_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	1.1e-169	36.1
WP_024127850.1\|8280_11244_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	1.4e-212	40.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP020354

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP020354_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020354_1

261523-261711

Orphan

Consensus_repeat	Method
TGCAAGTTGGCGGGGCCCCAACAN	CRT

3 spacers

The CRISPR arrays of NZ_CP020354_1

>merge|NZ_CP020354|1|261523-261711|CRT
GTTATATTGGCGGGCCCCAACATAGAAGCTGGCGGAAAGTCAGCATACAATAATGTGCAAGTTGGCGGGGCCCCAACACAGAGAATTTCGAAAAGAAATTCTACAGGCAATGCAAGTTGGCGGGGCCCCAACATAGAAGCTGGCGGAAAGTCAGCATACAATAATGTGCAAGTTGGCGGGGCCCCAACA

>NZ_CP020354|1|1|261523-261711|CRT
GTTATATTGGCGGGCCCCAACAT	AGAAGCTGGCGGAAAGTCAGCATACAATAATG
TGCAAGTTGGCGGGGCCCCAACA	CAGAGAATTTCGAAAAGAAATTCTACAGGCAA
TGCAAGTTGGCGGGGCCCCAACA	TAGAAGCTGGCGGAAAGTCAGCATACAATAATG
TGCAAGTTGGCGGGGCCCCAACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020354.1\|WP_000645456.1\|256262_257003_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|184495
NZ_CP020354.1\|WP_000164005.1\|260020_261457_+\|6-phospho-beta-glucosidase	unknown	unknown	gnl\|CDD\|181973
NZ_CP020354.1\|WP_000925394.1\|254520_256260_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225814
NZ_CP020354.1\|WP_000747873.1\|263957_264362_-\|D-ribose-pyranase	unknown	unknown	gnl\|CDD\|183318
NZ_CP020354.1\|WP_001066553.1\|267931_269308_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP020354.1\|WP_001789860.1\|262783_262918_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_000031274.1\|262003_262765_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP020354.1\|WP_000757871.1\|265489_266488_-\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NZ_CP020354.1\|WP_000975364.1\|251722_253444_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|376098
NZ_CP020354.1\|WP_000066938.1\|259213_260005_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225101
NZ_CP020354.1\|WP_000182741.1\|263015_263930_-\|ribokinase	unknown	unknown	gnl\|CDD\|274000
NZ_CP020354.1\|WP_000608831.1\|253587_254262_+\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	unknown	unknown	gnl\|CDD\|183940
NZ_CP020354.1\|WP_000337383.1\|269541_270534_+\|linear-amide-C-N-hydrolase	unknown	unknown	gnl\|CDD\|225591
NZ_CP020354.1\|WP_106669509.1\|264376_265258_-\|ribose-transporter-RbsU	unknown	unknown	gnl\|CDD\|284268
NZ_CP020354.1\|WP_000922329.1\|258360_259065_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_CP020354.1\|WP_000736793.1\|270859_271810_+\|glycine-glycine-endopeptidase-LytM	unknown	unknown	gnl\|CDD\|226451
NZ_CP020354.1\|WP_001159767.1\|266867_267260_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_000240920.1\|250001_251690_+\|CDP-glycerol-glycerophosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|367953
NZ_CP020354.1\|WP_000607067.1\|257551_258253_+\|antiholin-like-protein-LrgB	unknown	unknown	gnl\|CDD\|179810
NZ_CP020354.1\|WP_001792906.1\|257115_257559_+\|antiholin-like-murein-hydrolase-modulator-LrgA	unknown	unknown	gnl\|CDD\|235222

Protein	Function_ID	Function_description	E-value
NZ_CP020354.1\|WP_000645456.1\|256262_257003_+\|DNA-binding-response-regulator	gnl\|CDD\|184495	PRK14084, PRK14084, DNA-binding response regulator.	4.37999e-152
NZ_CP020354.1\|WP_000164005.1\|260020_261457_+\|6-phospho-beta-glucosidase	gnl\|CDD\|181973	PRK09589, celA, 6-phospho-beta-glucosidase; Reviewed.	0
NZ_CP020354.1\|WP_000925394.1\|254520_256260_+\|sensor-histidine-kinase	gnl\|CDD\|225814	COG3275, LytS, Putative regulator of cell autolysis [Signal transduction mechanisms].	0
NZ_CP020354.1\|WP_000747873.1\|263957_264362_-\|D-ribose-pyranase	gnl\|CDD\|183318	PRK11797, PRK11797, D-ribose pyranase; Provisional.	1.143e-69
NZ_CP020354.1\|WP_000031274.1\|262003_262765_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.48144e-27
NZ_CP020354.1\|WP_000757871.1\|265489_266488_-\|LacI-family-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	3.55591e-100
NZ_CP020354.1\|WP_000975364.1\|251722_253444_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|376098	pfam18674, TarS_C1, TarS beta-glycosyltransferase C-terminal domain 1. Beta-glycosyltransferase TarS is an enzyme responsible for the glycosylation of wall teichoic acid polymers of the S. aureus cell wall, a process that has been shown to be specifically responsible for methicillin resistance in MRSA. It contains a trimerization domain composed of tandem carbohydrate binding motifs.The two C-terminally localized regions composed of a series of beta-sheets participate in an extensive trimerization interface and they assume an immunoglobulin-like fold. It is suggested that both carbohydrate binding domains may be involved in polyRboP binding, however unlike pullulanase, the CBMs of TarS are involved in the formation of an extensive trimerization interface.	6.38971e-35
NZ_CP020354.1\|WP_000066938.1\|259213_260005_+\|hypothetical-protein	gnl\|CDD\|225101	COG2190, NagE, Phosphotransferase system IIA components [Carbohydrate transport and metabolism].	2.16102e-54
NZ_CP020354.1\|WP_000182741.1\|263015_263930_-\|ribokinase	gnl\|CDD\|274000	TIGR02152, Putative_ribokinase, ribokinase. This model describes ribokinase, an enzyme catalyzing the first step in ribose catabolism. The rbsK gene encoding ribokinase typically is found with ribose transport genes. Ribokinase belongs to the carbohydrate kinase pfkB family (pfam00294). In the wide gulf between the current trusted (360 bit) and noise (100 bit) cutoffs are a number of sequences, few of which are clustered with predicted ribose transport genes but many of which are currently annotated as if having ribokinase activity. Most likely some have this function and others do not. [Energy metabolism, Sugars].	1.0203e-141
NZ_CP020354.1\|WP_000608831.1\|253587_254262_+\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	gnl\|CDD\|183940	PRK13276, PRK13276, iron-sulfur cluster repair di-iron protein ScdA.	7.18502e-154
NZ_CP020354.1\|WP_000337383.1\|269541_270534_+\|linear-amide-C-N-hydrolase	gnl\|CDD\|225591	COG3049, COG3049, Penicillin V acylase and related amidases [Cell envelope biogenesis, outer membrane].	5.1195e-152
NZ_CP020354.1\|WP_106669509.1\|264376_265258_-\|ribose-transporter-RbsU	gnl\|CDD\|284268	pfam06800, Sugar_transport, Sugar transport protein. This is a family of bacterial sugar transporters approximately 300 residues long. Members include glucose uptake proteins, ribose transport proteins, and several putative and hypothetical membrane proteins probably involved in sugar transport across bacterial membranes. These members are transmembrane proteins which are usually 5+5 duplications. This model recognizes a set of five TMs,.	1.15726e-116
NZ_CP020354.1\|WP_000922329.1\|258360_259065_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	3.76404e-62
NZ_CP020354.1\|WP_000736793.1\|270859_271810_+\|glycine-glycine-endopeptidase-LytM	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	2.05354e-32
NZ_CP020354.1\|WP_001066553.1\|267931_269308_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	7.58117e-30
NZ_CP020354.1\|WP_000240920.1\|250001_251690_+\|CDP-glycerol-glycerophosphotransferase-family-protein	gnl\|CDD\|367953	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.	4.42901e-119
NZ_CP020354.1\|WP_000607067.1\|257551_258253_+\|antiholin-like-protein-LrgB	gnl\|CDD\|179810	PRK04288, PRK04288, antiholin-like protein LrgB; Provisional.	5.86643e-124
NZ_CP020354.1\|WP_001792906.1\|257115_257559_+\|antiholin-like-murein-hydrolase-modulator-LrgA	gnl\|CDD\|235222	PRK04125, PRK04125, antiholin-like protein LrgA.	8.44339e-64

>NZ_CP020354.1|WP_000164005.1|260020_261457_+|6-phospho-beta-glucosidase
MTKLPQNFMWGGALAANQFEGGYEKGGKGLSVIDVMTSGAHGKARQITESIDLNHYYPNHEGIDFYHRYKEDIALFKEMGLKCLRTSIAWTRIFPNGDEDVPNEEGLAFYDRIFDELIAQGIEPVVTLSHFEMPLHLAKHYGGFRNREVVDYFVHFARVVFERYKDKVTYWMTFNEINNQMDTSNPIFLWTNSGVALTENDNPEEVLYQVAHHELLASALAVRLGKEINPKFKIGTMISHVPIYPYSCHPKDMMEAQIANRLRFFFPDVQVRGYYPSYAKKMLARKGYDVGWQEGDDSILQQGTVDYIGFSYYMSTAVKHDVDTTVKNNIVNGGLNHSVENPHIATSDWGWAIDPDGLRYTLNVLYDRYQLPLFIVENGFGAVDEVVDGHIHDDYRIEYLKAHITAAIEAVDQDGVDLIGYTPWGIIDIVSFTTGEMKKRYGLIYVDRDNDGHGTMERLKKDSFYWYQQVIASNGDKL
>NZ_CP020354.1|WP_000066938.1|259213_260005_+|hypothetical-protein
MSNKYKEQAQDILTAVGGVENIVDATYDTKCITIHMQHTIPSTANEVKQIVDVTSVAENDTQLVIKLNGNVDEVYQQLQRLIKNANVEESENTDNINSQDTSYTPQVKVTTPILVKAPIAGRRILLKEVRDSIFREKMVGEGLAIKAHEESKVIAPFNGLISMIVPTKHAVGIQSEDGVDIVIHIGVNTVDLEGKGFKCFVKQNDHVEAGQTLLQFDQQYIQQQGYNADVIVVISNSADLGKVELTMNEIITTEDVIFKIFKN
>NZ_CP020354.1|WP_000922329.1|258360_259065_-|GntR-family-transcriptional-regulator
MLKYEHIAKQLNAFIHQSNFKPGDKLPSVTQLKERYQVSKSTIIKALGLLEQDGLIYQAQGSGIYVRNIADANRINVFKTNGFSKSLGEHRMTSKVLVFKEIATPPKSVQDELQLNADDTVYYLERLRFVDDDVLCIEYSYYHKEIVKYLNDDIAKGSIFDYLESNMKLRIGFSDIFFNVDQLTSSEASLLQLSTGEPCLRYHQTFYTMTGKPFDSSDIVFHYRHAQFYIPSKK
>NZ_CP020354.1|WP_000607067.1|257551_258253_+|antiholin-like-protein-LrgB
MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSMVFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIGIGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILNGVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVGVVVVAVVPVFVAIFF
>NZ_CP020354.1|WP_001792906.1|257115_257559_+|antiholin-like-murein-hydrolase-modulator-LrgA
MVVKQQKDASKPAHFFHQVIVIALVLFVSKIIESFMPIPMPASVIGLVLLFVLLCTGAVKLGEVEKVGTTLTNNIGLLFVPAGISVVNSLGVISQAPFLIIGLIIVSTILLLICTGYVTQIIMKVTSRSKGDKVTKKIKIEEAQAHD
>NZ_CP020354.1|WP_000645456.1|256262_257003_+|DNA-binding-response-regulator
MKALIIDDEPLARNELTYLLNEIGGFEEINEAENVKETLEALLINQYDIIFLDVNLMDENGIELGAKIQKMKEPPAIIFATAHDQYAVQAFELNATDYILKPFGQKRIEQAVNKVRATKAKDDNSASAIANDMSANFDQSLPVEIDDKIHMLKQQNIIGIGTHNGITTIHTTNHKYETTEPLNRYEKRLNPAYFIRIHRSYIINTKHIKEVQQWFNYTYMVILTNGVKMQVGRSFMKDFKASIGLL
>NZ_CP020354.1|WP_000925394.1|254520_256260_+|sensor-histidine-kinase
MLLLERVGLIIILAYVLMNIPYFKNLMNRRRTWKARWQLCIIFSLFALMSNLTGIVIDHQHSLSGSVYFRLDDDVSLANTRVLTIGVAGLVGGPFVGLFVGVISGIFRVYMGGADAQVYLISSIFIGIIAGYFGLQAQRRKRYPSIAKSAMIGIVMEMIQMLSILTFSHDKAYAVDLISLIALPMIIVNSVGTAIFMSIIISTLKQEEQMKAVQTHDVLQLMNQTLPYFKEGLNRESAQQIAMIIKNLMKVSAVAITSKNEILSHVGAGSDHHIPTNEILTSLSKDVLKSGKLKEVHTKEEIGCSHPNCPLRAAIVIPLEMHGSIVGTLKMYFTNPNDLTFVERQLAEGLANIFSSQIELGEAETQSKLLKDAEIKSLQAQVSPHFFFNSINTISALVRINSEKARELLLELSYFFRANLQGSKQHTITLDKELSQVRAYLSLEQARYPGRFNININVEDKYRDVLVPPFLIQILVENAIKHAFTNRKQGNDIDVSVIKETATHVRIIVQDNGQGISKDKMHLLGETSVESESGTGSALENLNLRLKGLFGKSAALQFESTSSGTTFWCVLPYERQEEE
>NZ_CP020354.1|WP_000608831.1|253587_254262_+|iron-sulfur-cluster-repair-di-iron-protein-ScdA
MINKNDIVADVVTDYPKAADIFRSVGIDFCCGGQVSIEAASLEKKNVDLNELLQRLNDVEQTNTPGSLNPKFLNVSSLIQYIQAAYHEPLREEFKNLTPYVTKLSKVHGPNHPYLVELKETYDTFKNGMLEHMQKEDDVDFPKLIKYEQGEVVDDINTVIDDLVSDHIATGQLLVKMSDLTSSYEPPIEACGTWRLVYQRLKALEVLTHEHVHLENHVLFKKVS
>NZ_CP020354.1|WP_000975364.1|251722_253444_+|glycosyltransferase-family-2-protein
MMKFSVIVPTYNSEKYITELLNSLAKQDFPKTEFEVVVVDDCSTDQTLQIVEKYRNKLNLKVSQLETNSGGPGKPRNVALKQAEGEFVLFVDSDDYINKETLKDAAAFIDEHHSDVLLIKMKGVNGRGVPQSMFKETAPEVTLLNSRIIYTLSPTKIYRTTLLKDNDIYFPEELKSAEDQLFTMKAYLNANRISVLSDKAYYYATKREGEHMSSAYVSPEDFYEVMRLIAVEILNADLEEAHKDQILAEFLNRHFSFSRTNGFSLKVKLEDQPQWINALGDFIQAVPERVDALVMSKLRPLLHYARAKDIDNYRTVEESYRQGQYYRFDIVDGKLNIQFNEGEPYFEGIDIAKPKVKMTAFKFDNHKIVTELTLNEFMIGEGHYDVRLKLHSRNKKHTMYVPLSVNANKQYRFNIMLEDIKAYLPKEKIWDVFLEVQIGTEVFEVRVGNQRNKYAYTAETSALIHLNNDFYRLTPYFTKDFNNISLYFTAITLTDSISLKLKGKNKIILTGLDLGYVFEEGMASVVLKDDMIMGMLSQTSENEVEILLSKDIKKRDFKNIVKLNTAHMTYSLK
>NZ_CP020354.1|WP_000240920.1|250001_251690_+|CDP-glycerol-glycerophosphotransferase-family-protein
MVKSKIYIDKIYWERVQLFVEGHSENLDLEDSNFVLRNLTETRTMKANDVKIDGNQFVCRFNVAILDNGYYLPEDKYLLVNEQELDYIAQLNPDVINDAYQNLKPEQEEEYNELETQNGKINFLLQTYLKEFRKGGISKKTVYTVTPEISSDVNEFVLDVVVTTPEVKSIYIVRKYKELRKYFRKQSFNTRQFIFKAIFNTTKFFHLKKGNTVLFTSDSRPTMSGNFEYIYNEMLRQNLDKKYDIHTVFKANITDRRGIIDKFRLPYLLGKADYIFVDDFHPLIYTVRFRRSQEVIQVWHAVGAFKTVGFSRTGKKGGPFIDSLNHRSYTKAYVSSETDIPFYAEAFGIKEKNVVPTGVPRTDVLFDEAYATQIKQEMEDELPIIKGKKVILFAPTFRGSGHGTAHYPFFKIDFERLARYCEKNNAVVLFKMHPFVKNRLNIADKHKQYFVDVSDFREVNDILFITDLLISDYSSLIYEYAVFKKPMIFYAFDLEDYITTRDFYEPYESFVPGKIVQSFDALMDALDNEDYEGEKVIPFLDKHFKYQDGRSSERLVRNLFGS
>NZ_CP020354.1|WP_000031274.1|262003_262765_-|class-I-SAM-dependent-methyltransferase
MSKEAGHTFLAKLGKTRLRPGGKEATDWLIQQGAFSQDKQVLEVACNMCTTSIYLAHTYGCHIQGVDINKKALEKAQENISAAGLESYIQVQQANAVKLPFDDNQFDIVLNEAMLTMLPITIKEKALREYYRVLKPGGILLTHDIVIVNESHATHVVKSLSAAINVNVSPQTKLGWLDLYNQAGFNHVHYHTGPMSLMTPKGLIYDEGIVGTIKIINNALKKENRPMFCKMFKTMTKLRKDMNYITFVAKKED
>NZ_CP020354.1|WP_001789860.1|262783_262918_+|hypothetical-protein
MIIIIINIAYLYAIIWKLKRLQKIVTSFITKHESTSIGLVENYF
>NZ_CP020354.1|WP_000182741.1|263015_263930_-|ribokinase
MTNKVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGANQAIATARMQADTTFITKIGTDGVADFILEDFKAAHIDTSYIIKTAEAKTGQAFITVNAEGQNTIYVYGGANMTMTPEDVINAKDAIINADFVVAQLEVPIPAIISAFEIAKAHGVTTVLNPAPAKALPNELLSLIDIIVPNETEAELLSGIKVTNEQSMKDNANYFLSIGIKTVLITLGKQGTYFATKNQSQHIEAYKVNAIDTTAAGDTFIGAFVSRLNKSQDNLADAIDFGNKASSLTVQKHGAQASIPLLEEVNQV
>NZ_CP020354.1|WP_000747873.1|263957_264362_-|D-ribose-pyranase
MKKSAVLNEHISKAIATIGHFDLLTINDAGMPIPNDHRRIDLAVTKNLPRFIDVLATVLEEMEIQKIYLAEEIKEHNPTQLQQIKQLISSEIEIIFIPHEEMKSNLAHPLNKGNIRTGETTPYSNIALESNVTF
>NZ_CP020354.1|WP_106669509.1|264376_265258_-|ribose-transporter-RbsU
MSIVALLIGLGPLIGWGFFPTVASKFGGKPVHQIIGVTVGTLIFAIILAVVTSSGFPTGTNLLFALLSGAGWGFGQIITFKAFELVGSSRAMPVTTAFQLLGASLWGVFALGNWPGIGHKIIGFTALVVILIGARMTVWSERKEASNAKNLRRAVVLLLIGEFGYWLYSAAPQATSIDGLTAFLPQAMGMVIVAVIYGFMNMKAENPFRNKITWLQIISGFFFAFGALTYLISAQPNMNGLATGFILSQTSVVLATLTGIYFLKQHKTSKEMVITIIGLVLILVAASVTVFIK
>NZ_CP020354.1|WP_000757871.1|265489_266488_-|LacI-family-transcriptional-regulator
MKKVSIKDVAREAGVSVTTVSHILNHHDSRFSATTIKNVHAVSERLGYAPNKHAKQLRGSKIQTIGVILPSLTNPFFSALMQSIHDHKPSDVDLCFLTSTATDLYDNIKHLIDRGIDGLIIAQYISSPDALNNYLKKHHVPYVVLDQNDHQGYTDFVRTNEYQGGQLAAQHLIELGHNNMMIVAPYDMMANMSTRVAGFVDTLRANQLPEPQIVHTELSKRGGLTIVDDIMVQSATAIFAINDELAIGILRGLIEHGISIPKDISLIGYDDIDYAAYVSPPLTTVAQPITDIGKTSLTLLLQRLQHLDKSIDMIELPTTLKIRATTGYHLSN
>NZ_CP020354.1|WP_001159767.1|266867_267260_+|hypothetical-protein
MQFKLKEEEIISFLELKYPEKEFEYGRLLVGQHKRDDLDVYYFGDTFLMCTIISFKTFEIKETVELSYDVVNRIVLKDGWLFRKMRIETMQKVLKYGTSKLMLTDFQKDNYNKYIQGQKQRVIFENGHFV
>NZ_CP020354.1|WP_001066553.1|267931_269308_-|MFS-transporter
MNNTQSSPRSNIIIAIMLSALTYWLFAQSFINIGPLVGQTYQTSPAVLNLSISLTSFATGIFMVAAGDIADKIGQLRMTYMGLIISMFASLLLIISDITALLIIGRILQGLSAAILLPSTVGVLNNQFKGEHLRRAISYLMISTVGGIGLAGVIGGLIATNFGWQTNFIISIVIAFIAILLLKGTPEKVSQHSHRHPFDYKGMSIFAVMIGSFTLLLTQGFEQGWFSTFSFICLSIFIITTLIFIIIERRHEVPFIDFSVLRNRPFIGAFLNNFVLNSGLGVTVVFFIYAQTHLGLSAAQSGLVTLPYAIVAVAMIRLGEKATLRFGGKLMLIIGPLFPVIGITIISMTQLSASQYVIAVIIGFVICAIGNGLVATPGLTIAIFSMPNEKVGLATGLYKMSGTLGGAFGIALSTTVFSMLQLNYAPSVAATVTFIVSIVLMILGSLSAYMIIPKTVKS
>NZ_CP020354.1|WP_000337383.1|269541_270534_+|linear-amide-C-N-hydrolase
MCTGFTIQTLNNQVLLGRTMDYDYPLDGSPAVTPRNYRWTSRTGTTGQTQYGFIGTGTDMEGFIYGDGVNEHGVAISTQYFRGYSSYGSTHKAGAMNITQNEIVTWILGYTTSIEDMKQQASQIHVVAVYLNDIGEVPPLHYHVSDATGHSVEVSFKEGEVVIKDNPIGVLTNHPDLDWHYSNLRQYINISPYPATAKLLEGVTIEPLGNEAGTFGLPGGFTSTERFVRMAFMKANIAQNNDKEMDLMNAFYLLDAVNIPIGIVRPHDADNHYTMYQTVINLTTRTLYIKYYGSNELVALKLTDDLINRKDMTIFKPEKHITIRKLNDNQ
>NZ_CP020354.1|WP_000736793.1|270859_271810_+|glycine-glycine-endopeptidase-LytM
MKKLTAAAIATMGFATFTMAHQADAAETTNTQQAHTQMSTQSQDVSYGTYYTIDSNGDYHHTPDGNWNQAMFDNKEYSYTFVDAQGHTHYFYNCYPKNANANGSGQTYVNPAIAGDNNDYTASQSQQHINQYGYQSNVGPDASYYSHSNNNQAYNSHDGNGKVNYPNGTSNQNGGSASKATASGHAKDASWLTSRKQLQPYGQYHGGGAHYGVDYAMPENSPVYSLTDGTVVQAGWSNYGGGNQVTIKEANSNNYQWYMHNNRLTVSAGDKVKAGDQIAYSGSTGNSTAPHVHFQRMSGGIGNQYAVDPTSYLQSR

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Crispr_ID: NZ_CP020354_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020354_2

1090788-1090879

Orphan

Consensus_repeat	Method
TATAATGATTAAAAATCAAAGAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020354_2

>merge|NZ_CP020354|2|1090788-1090879|CRISPRCasFinder
TATAATGATTAAAAATCAAAGAGGAACAGCGGAATACAGATGATGCTTCGCACAACTGCATAAAAGCCTCTAATGATTAAAAATCAAAGAGG

>NZ_CP020354|2|1|1090788-1090879|CRISPRCasFinder
TATAATGATTAAAAATCAAAGAGG	AACAGCGGAATACAGATGATGCTTCGCACAACTGCATAAAAGCC
TCTAATGATTAAAAATCAAAGAGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020354.1\|WP_001246696.1\|1081535_1082612_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_000435384.1\|1085987_1086728_+\|RNA-methyltransferase	unknown	unknown	gnl\|CDD\|223640
NZ_CP020354.1\|WP_001249305.1\|1094768_1097117_+\|endonuclease-MutS2	unknown	unknown	gnl\|CDD\|234750
NZ_CP020354.1\|WP_000046704.1\|1092185_1092452_+\|cell-division-protein-ZapA	unknown	unknown	gnl\|CDD\|172616
NZ_CP020354.1\|WP_000818278.1\|1100698_1102465_+\|succinate-dehydrogenase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|236319
NZ_CP020354.1\|WP_001242420.1\|1084526_1085261_+\|class-B-sortase	unknown	unknown	gnl\|CDD\|226898
NZ_CP020354.1\|WP_000908992.1\|1088165_1090568_+\|phenylalanine--tRNA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234804
NZ_CP020354.1\|WP_001018928.1\|1097289_1097604_+\|thioredoxin	unknown	unknown	gnl\|CDD\|200072
NZ_CP020354.1\|WP_001788625.1\|1097666_1097762_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_000139712.1\|1102464_1103280_+\|succinate-dehydrogenase-iron-sulfur-subunit	unknown	unknown	gnl\|CDD\|181515
NZ_CP020354.1\|WP_001220199.1\|1082608_1083487_+\|heme-ABC-transporter-substrate-binding-protein-IsdE	unknown	unknown	gnl\|CDD\|274706
NZ_CP020354.1\|WP_000160836.1\|1079591_1080644_-\|LPXTG-anchored-heme-scavenging-protein-IsdA	unknown	unknown	gnl\|CDD\|227676
NZ_CP020354.1\|WP_000670950.1\|1085279_1085603_+\|staphylobilin-forming-heme-oxygenase-IsdG	unknown	unknown	gnl\|CDD\|139480
NZ_CP020354.1\|WP_000789821.1\|1080852_1081536_+\|heme-uptake-protein-IsdC	unknown	unknown	gnl\|CDD\|274705
NZ_CP020354.1\|WP_000079317.1\|1100032_1100647_+\|succinate-dehydrogenase-cytochrome-B558	unknown	unknown	gnl\|CDD\|239577
NZ_CP020354.1\|WP_001566586.1\|1083496_1084465_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223682
NZ_CP020354.1\|WP_000003566.1\|1087107_1088166_+\|phenylalanine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|234780
NZ_CP020354.1\|WP_000234068.1\|1092452_1092974_+\|CvpA-family-protein	unknown	unknown	gnl\|CDD\|224205
NZ_CP020354.1\|WP_000390529.1\|1097927_1099709_+\|excinuclease-ABC-subunit-UvrC	unknown	unknown	gnl\|CDD\|234792
NZ_CP020354.1\|WP_000161940.1\|1093046_1094759_+\|DNA-polymerase/3'-5'-exonuclease-PolX	unknown	unknown	gnl\|CDD\|236311

Protein	Function_ID	Function_description	E-value
NZ_CP020354.1\|WP_000435384.1\|1085987_1086728_+\|RNA-methyltransferase	gnl\|CDD\|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	3.43228e-78
NZ_CP020354.1\|WP_001249305.1\|1094768_1097117_+\|endonuclease-MutS2	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	0
NZ_CP020354.1\|WP_000046704.1\|1092185_1092452_+\|cell-division-protein-ZapA	gnl\|CDD\|172616	PRK14126, PRK14126, cell division protein ZapA; Provisional.	1.04877e-21
NZ_CP020354.1\|WP_000818278.1\|1100698_1102465_+\|succinate-dehydrogenase-flavoprotein-subunit	gnl\|CDD\|236319	PRK08641, sdhA, succinate dehydrogenase flavoprotein subunit; Reviewed.	0
NZ_CP020354.1\|WP_001242420.1\|1084526_1085261_+\|class-B-sortase	gnl\|CDD\|226898	COG4509, COG4509, Uncharacterized protein conserved in bacteria [Function unknown].	2.78558e-128
NZ_CP020354.1\|WP_000908992.1\|1088165_1090568_+\|phenylalanine--tRNA-ligase-subunit-beta	gnl\|CDD\|234804	PRK00629, pheT, phenylalanyl-tRNA synthetase subunit beta; Reviewed.	0
NZ_CP020354.1\|WP_001018928.1\|1097289_1097604_+\|thioredoxin	gnl\|CDD\|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	3.26685e-48
NZ_CP020354.1\|WP_000139712.1\|1102464_1103280_+\|succinate-dehydrogenase-iron-sulfur-subunit	gnl\|CDD\|181515	PRK08640, sdhB, succinate dehydrogenase iron-sulfur subunit; Reviewed.	0
NZ_CP020354.1\|WP_001220199.1\|1082608_1083487_+\|heme-ABC-transporter-substrate-binding-protein-IsdE	gnl\|CDD\|274706	TIGR03659, heme_ABC_transporter_heme-binding_protein_isdE, heme ABC transporter, heme-binding protein isdE. This family of ABC substrate-binding proteins is observed primarily in close proximity with proteins localized to the cell wall and bearing the NEAT (NEAr Transporter, pfam05031) heme-binding domain. IsdE has been shown to bind heme and is involved in the process of scavenging heme for the purpose of obtaining iron.	9.77537e-156
NZ_CP020354.1\|WP_000160836.1\|1079591_1080644_-\|LPXTG-anchored-heme-scavenging-protein-IsdA	gnl\|CDD\|227676	COG5386, COG5386, Cell surface protein [Cell envelope biogenesis, outer membrane].	8.33511e-123
NZ_CP020354.1\|WP_000670950.1\|1085279_1085603_+\|staphylobilin-forming-heme-oxygenase-IsdG	gnl\|CDD\|139480	PRK13312, PRK13312, staphylobilin-forming heme oxygenase IsdG.	3.35893e-67
NZ_CP020354.1\|WP_000789821.1\|1080852_1081536_+\|heme-uptake-protein-IsdC	gnl\|CDD\|274705	TIGR03656, IsdC, heme uptake protein IsdC. Isd proteins are iron-regulated surface proteins found in Bacillus, Staphylococcus and Listeria species and are responsible for heme scavenging from hemoproteins. The IsdC protein consists of an N-terminal hydrophobic signal sequence, a central NEAT (NEAr Transporter, pfam05031) domain, which confers the ability to bind heme, and a C-terminal SrtB processing signal which targets the protein to the cell wall. IsdC is believed to make a direct contact with, and transfer heme to, the heme-binding component (IsdE) of an ABC transporter in the cytoplasmic membrane, and to receive heme from other NEAT-containing heme-binding proteins also localized in the cell wall.	2.0626e-97
NZ_CP020354.1\|WP_000079317.1\|1100032_1100647_+\|succinate-dehydrogenase-cytochrome-B558	gnl\|CDD\|239577	cd03497, SQR_TypeB_1_TM, Succinate:quinone oxidoreductase (SQR) Type B subfamily 1, transmembrane subunit; composed of proteins similar to Bacillus subtilis SQR. SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Bacillus subtilis SQR reduces low potential quinones such as menaquinone. SQR is also called succinate dehydrogenase (Sdh) or Complex II and is part of the citric acid cycle and the aerobic respiratory chain. SQR is composed of a flavoprotein catalytic subunit, an iron-sulfur protein and one or two hydrophobic transmembrane subunits. Members of this subfamily are classified as Type B as they contain one transmembrane subunit and two heme groups. The heme and quinone binding sites reside on the transmembrane subunit. The transmembrane subunit of Bacillus subtilis SQR is also called Sdh cytochrome b558 subunit. The structural arrangement allows efficient electron transfer between the catalytic subunit, through iron-sulfur centers, and the transmembrane subunit containing the electron acceptor (quinone). The reversible reduction of quinone is an essential feature of respiration, allowing transfer of electrons between respiratory complexes.	2.37018e-87
NZ_CP020354.1\|WP_001566586.1\|1083496_1084465_+\|iron-ABC-transporter-permease	gnl\|CDD\|223682	COG0609, FepD, ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism].	1.24727e-61
NZ_CP020354.1\|WP_000003566.1\|1087107_1088166_+\|phenylalanine--tRNA-ligase-subunit-alpha	gnl\|CDD\|234780	PRK00488, pheS, phenylalanyl-tRNA synthetase subunit alpha; Validated.	0
NZ_CP020354.1\|WP_000234068.1\|1092452_1092974_+\|CvpA-family-protein	gnl\|CDD\|224205	COG1286, CvpA, Uncharacterized membrane protein, required for colicin V production [General function prediction only].	4.13485e-29
NZ_CP020354.1\|WP_000390529.1\|1097927_1099709_+\|excinuclease-ABC-subunit-UvrC	gnl\|CDD\|234792	PRK00558, uvrC, excinuclease ABC subunit UvrC.	0
NZ_CP020354.1\|WP_000161940.1\|1093046_1094759_+\|DNA-polymerase/3'-5'-exonuclease-PolX	gnl\|CDD\|236311	PRK08609, PRK08609, DNA polymerase/3'-5' exonuclease PolX.	0

>NZ_CP020354.1|WP_000908992.1|1088165_1090568_+|phenylalanine--tRNA-ligase-subunit-beta
MLISNEWLKEYVTIDDSVSNLAERITRTGIEVDDLIDYTKDIKNLVVGFVKSKEKHPDADKLNVCQVDIGEDEPVQIVCGAPNVDAGQYVIVAKVGGRLPGGIKIKRAKLRGERSEGMICSLQEIGISSNYIPKSFESGIYVFSESQVPGTDALQALYLDDQVMEFDLTPNRADALSMIGTAYEVAALYNTKMTKPETTSNELELSANDELTVTIENEDKVPYYSARVVHDVTIEPSPIWMQARLIKAGIRPINNVVDISNYVLLEYGQPLHMFDQDAIGSQQIVVRQANEGEKMTTLDDTERELLTSDIVITNGQTPIALAGVMGGDFSEVKEQTSNIVIEGAIFDPVSIRHTSRRLNLRSESSSRFEKGIATEFVDEAVDRACYLLQTYANGKVLKDRVSSGELGAFITPIDITADKINRTIGFDLSQNDIVTIFNQLGFDTEINDDVITVQVPSRRKDITIKEDLIEEVARIYGYDDIPSTLPVFEKVTSGQLTDRQYKTRMVKEVLEGAGLDQAITYSLVSKEDATAFAMQQRQTIDLLMPMSEAHASLRQSLLPHLIEAASYNVARKNKDVKLFEIGNVFFANGEGELPDQVEYLSGILTGDYVVNQWQGKKETVDFYLAKGVVDRVSEKLNLEFSYRRADIDGLHPGRTAEILLENKVVGFIGELHPTLAADNDLKRTYVFELNFDALMAVSVGYINYQPIPRFPGMSRDIALEVDQNIPAADLLSTIHAHGGNILKDTLVFDVYQGEHLEKGKKSIAIRLNYLDTEETLTDERVSKVQAEIEAALIEQGAVIR
>NZ_CP020354.1|WP_000003566.1|1087107_1088166_+|phenylalanine--tRNA-ligase-subunit-alpha
MSEQQTMSELKQQALVDINEANDERALQEVKVKYLGKKGSVSGLMKLMKDLPNEEKPAFGQKVNELRQTIQNELDERQQMLVKEKLNKQLAEETIDVSLPGRHIEIGSKHPLTRTIEEIEDLFLGLGYEIVNGYEVEQDHYNFEMLNLPKSHPARDMQDSFYITDEILLRTHTSPVQARTMESRHGQGPVKIICPGKVYRRDSDDATHSHQFTQIEGLVVDKNVKMSDLKGTLELLAKKLFGADREIRLRPSYFPFTEPSVEVDVSCFKCKGKGCNVCKHTGWIEILGAGMVHPNVLEMAGFDSSEYSGFAFGMGPDRIAMLKYGIEDIRHFYTNDVRFLDQFKAVEDRGDM
>NZ_CP020354.1|WP_000435384.1|1085987_1086728_+|RNA-methyltransferase
MEQITSAQNNRIKQANKLKKKRERDKTGLALIEGVHLIEEAYQSGIVITQLFAIEPVRLDQQIIAYAQEVFEINMKVAESLSGTVTPQGFFAIIEKPHYDISKAQQVLLIDRVQDPGNLGTLIRTADAAGMDAVIMEKGTTDPYQDKVLRASQGSVFHLPVMTQDLDTFITQFNGPVYGTALENAVAYKEVTSSDSFALLLGNEGEGVNPELLAHTTQNLIIPIYGKAESLNVAIAGSILLYHLKG
>NZ_CP020354.1|WP_000670950.1|1085279_1085603_+|staphylobilin-forming-heme-oxygenase-IsdG
MKFMAENRLTLTKGTAKDIIERFYTRHGIETLEGFDGMFVTQTLEQEDFDEVKILTVWKSKQAFTDWLKSDVFKAAHKHVRSKNEDESSPIINNKVITYDIGYSYMK
>NZ_CP020354.1|WP_001242420.1|1084526_1085261_+|class-B-sortase
MRMKRFLTIVQILLVVIIIIFGYKIVQTYIEDKQERANYEKLQQKFQMLMSKHQAHVRPQFESLEKINKDIVGWIKLSGTSLNYPVLQGKTNHDYLNLDFEREHRRKGSIFMDFRNELKNLNHNTILYGHHVGDNTMFDVLEDYLKQSFYEKHKIIEFDNKYGKYQLQVFSAYKTTTKDNYIRTDFENDQDYQQFLDETKRKSVINSDVNVTVKDRIMTLSTCEDAYSETTKRIVVVAKIIKVS
>NZ_CP020354.1|WP_001566586.1|1083496_1084465_+|iron-ABC-transporter-permease
MMIKNKKKLLFLCLLVILIATAYISFVTGTIKLSFNDLITKFTTGNNEAVDSIIDLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMRALCMLFIPQLYFYLPLLSFIGGLIPFLIIILLHSKFRFNAVSMILVGVALFVLLNGVLEILTQNPLMKIPQGLTMKIWSDVYILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWLLLVADLLGRVIQPPLEIPANAILMIVGGPMLIYLICQSQRNRI
>NZ_CP020354.1|WP_001220199.1|1082608_1083487_+|heme-ABC-transporter-substrate-binding-protein-IsdE
MRIIKYLTILVISVVILTSCQSSSSQESTKSGEFRIVPTTVALTMTLDKLDLPIVGKPTSYKTLPNRYKDVPEIGQPMEPNVEAVKKLKPTHVLSVSTIKDEMQPFYKQLNMKGYFYDFDSLKGMQKSITQLGDQFNRKAQAKELNDHLNSVKQKIENKAAKQKKHPKVLILMGVPGSYLVATDKSYIGDLVKIAGGENVIKVKDRQYISSNTENLLNINPDIILRLPHGMPEEVKKMFQKEFKQNDIWKHFKAVKNNHVYDLEEVPFGITANVDADKAMTQLYDLFYKDKK
>NZ_CP020354.1|WP_001246696.1|1081535_1082612_+|hypothetical-protein
MRNVKQIATKSIIAIISLGILTYTTMIGSVLADEIKYPSAKFNQPEAKDKTELTTSIFDEKIKENKALELLIFNQENKNVTEEQKLVDEKAQLISDMTGKIYLQVKLKGQIDKEQLVFQNDKNEEFPFVIKDEKDDTIVRILIEQHMDKINMHVKTLAEKKNLDNKEMVYSIHFKEKKVQHDDAKEVPSKHQNQENNQDQLKKDIDDKKDSQKSDTKERRTSLFTEKGLNDIPVQKDKVQQDSNKKIENERPKASGTLKVENSPPTIKKVENNHKEQPKHKDEKSKKEKKKVVEKEKALPAFNRDDDSKNSSQLSSDIKELDEPNHKKQYILFAAGIVLATILLISAHLYSRKRGNQV
>NZ_CP020354.1|WP_000789821.1|1080852_1081536_+|heme-uptake-protein-IsdC
MKNILKVFNTTILALIIIIATFSNSANAADSGTLNYEVYKYNTNDTSIANDYFNKPAKYIKKNGKLYVQITVNHSHWITGMSIEGHKENIISKNTAKDERTSEFEVSKLNGKIDGKIDVYIDEKVNGKPFKYDHHYNITYKFNGPTDVAGANAPGKDDKNSASGSDKGSDGTTTGQSESNSSNKDKVENPQTNAGTPAYIYAIPVASLALLIAITLFVRKKSKGNVE
>NZ_CP020354.1|WP_000160836.1|1079591_1080644_-|LPXTG-anchored-heme-scavenging-protein-IsdA
MTKHYLNSKYQSEQRSSAIKKITMGTASIILGSLVYIGADSQQVNAATEATNATNNQSTQVSQATSQPINFQVQKDGSSEKSHMDDYMQHPGKVIKQNNKYYFQTVLNNASFWKEYKFYNANNQELATTVVNDNKKADTRTINVAVEPGYKSLTTKVHIVVPQINYNHRYTTHLEFEKAIPTLADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEKVKPTVTTTSKVEDNHSTKVVSTDTTKDQTKTQTAHTVKTAQTAQEQNKVQTPVKDVATAKSESNNQAVSDNKSQQTNKVTKHNETPKQASKAKELPKTGLTSVDNFISTVAFATLALLGSLSLLLFKRKESK
>NZ_CP020354.1|WP_000046704.1|1092185_1092452_+|cell-division-protein-ZapA
MAQFKNKVNVSINDQLFTIVGEDNPEHIRYVAHLVDDKIKELGYKAAGLDTSRKAILTAVNIMHEKVLLEEENRRLKQQIHKLQQREQ
>NZ_CP020354.1|WP_000234068.1|1092452_1092974_+|CvpA-family-protein
MVIDFIIIIFFVYFVIVGFRRGFWLSMIHLSATIVSLWIASQFYKSIVERLIVFIPYPKTTAFNTTFAFHFNHLQNRFEAIVAFLMITLFCKFILYLIIVTFDKIIAYQNIHIFSRAMGMIVGVFMTIIVLHFTLYLLALYPNEALQHQLKISIVSHSLIFHIPYLSAFTINL
>NZ_CP020354.1|WP_000161940.1|1093046_1094759_+|DNA-polymerase/3'-5'-exonuclease-PolX
MTKKDVIKLLEQIATYMELKGENTFKISAYRKAAQSLELDERPLDEISDVTELKGIGKGVAEVINDYRETGESQYLQQLQEEVPEGLIPLLKIQGLGSKKIAKLYKELNIVDKASLQVACENGKVSELSGFAKKTEQNILEAVKQLGAKKDRYPIDQMRRLNQEIIDYIDTLNYIDQYSSAGSFRRFKEMSKDLDFIISTDNPKAVQQQLLNIPNKVKEVAVGNTKVSLELAYDDETIGVDFRLIEPSAFYHTLQHFTGSKEHNIRIRQLAKARDEKVSEYGIEQADGTLIQYDSEAKIYEHFNVNFIPPAMREDGSEFDKDLSNIITIDDINGDIHMHTTYSDGAFSIRDMVEANIAKGYKFMVITDHSQSLRVANGLQVERLLRQNEEIKALDKEYSEIDIYSGTEMDILPDGSLDYDDEILAQLDYVIGAIHQSFNQSEEQIMERLANACRNPYVRHIAHPTGRIIGRRDGYKPNIEQLMALAEETNTVLEINANPHRLDLNADIVRKYPNVKLTINTDAHHTNHLDFMNYGVATAQKGFVTKDRVINALSREAFKDFIENNIKLKK
>NZ_CP020354.1|WP_001249305.1|1094768_1097117_+|endonuclease-MutS2
MRQKTLDVLEFEKIKSLVANETISDLGLEKVSQMMPATNFETVVFQMEETDEIAQIYNKHRLPSLSGLSKVSAFIHRADIGGVLNVSELNLIKRLIQVQNQFKTFYNQLVEEDEGVKYPILDDKMNQLPVLTDLFQQINETCDTYDLYDNASYELQGIRSKISSTNQRIRQNLDRIVKSQANQKKLSDAIVTVRNERNVIPVKAEYRQDFNGIVHDQSASGQTLYIEPSSVVEMNNQISRLRHDEAIEKERILTQLTGYVAADKDALLVAEQVMGQLDFLIAKARYSRSIKGTKPIFKEERTVYLPKAYHPLLNRETVVANTIEFMEDIETVIITGPNTGGKTVTLKTLGLIIVMAQSGLLIPTLDGSQLSVFKNVYCDIGDEQSIEQSLSTFSSHMTNIVEILKHADKHSLVLFDELGAGTDPSEGAALAMSILDHVRKIGSLVMATTHYPELKAYSYNREGVMNASVEFDVDTLSPTYKLLMGVPGRSNAFDISKKLGLSLNIINKAKTMIGTDEKEINEMIESLEHNYKRVETQRLELDRLVKEAEQVHDDLSKQYQQFQNYEKSLIEEAKEKANQKIKAATKEADDIIKDLRQLREQKGADVKEHELIDKKKRLDDHYEAKSIKQNVQKQKYDKIVAGDEVKVLSYGQKGEVLEIVNDEEAIVQMGIIKMKLPIEDLEKKQKEKVKPTKMVTRQNRQTIKTELDLRGYRYEDALIELDQYLDQAVLSNYEQVYIIHGKGTGALQKGVQQHLKKHKSVSDFRGGMPSEGGFGVTVATLK
>NZ_CP020354.1|WP_001018928.1|1097289_1097604_+|thioredoxin
MAIVKVTDADFDSKVESGVQLVDFWATWCGPCKMIAPVLEELAADYEGKADILKLDVDENPSTAAKYEVMSIPTLIVFKDGQPVDKVVGFQPKENLAEVLDKHL
>NZ_CP020354.1|WP_001788625.1|1097666_1097762_-|hypothetical-protein
MLDYHLTFIDLLIPPFSSRKQYDDLSFNFLY
>NZ_CP020354.1|WP_000390529.1|1097927_1099709_+|excinuclease-ABC-subunit-UvrC
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLLELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDKLCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKIMSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMIQSVVDTKIVQPARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSAMVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVAGLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGNKRKTLLLRSFGSIKKMKEATLEDFKNIGIPENVAKNLHEQLHK
>NZ_CP020354.1|WP_000079317.1|1100032_1100647_+|succinate-dehydrogenase-cytochrome-B558
MAQSKNEFYLRRIHSLLGIIPIGAFLVVHLLVNHQATQGAEAFNKASNFMESLPFLIIVEFLFIYIPLLYHGLFGIHIAFTAKENVGHYSIFRNWMFFFQRVSGILTFIFIGIHLWQTRLQKAFYGKEVNYDLMHETLQHPGWAIFYIICIIAVVFHFANGLWSFLVTWGGLQSPKSQRVFTWVSLIVFLVISYIGVTAIIAFM
>NZ_CP020354.1|WP_000818278.1|1100698_1102465_+|succinate-dehydrogenase-flavoprotein-subunit
MAEKHLIVVGGGLAGLMSTIKAAEKGAHVDLFSVVPVKRSHSVCAQGGINGAVNTKGEGDSPWIHFDDTVYGGDFLANQPPVKAMTEAAPKIIHLLDRMGVMFNRTNEGLLDFRRFGGTLHHRTAYAGATTGQQLLYALDEQVRAYEVDGLVTKYEGWEFLGIVKGDDDSARGIVAQNMTTAEIETFGSDAVIMATGGPGIIFGKTTNSMINTGSAASIVYQQGAIYANGEFIQIHPTAIPGDDKLRLMSESARGEGGRIWTYKDGKPWYFLEEKYPDYGNLVPRDIATREIFDVCINQKLGINGENMVYLDLSHKDPHELDVKLGGIIEIYEKFTGDDPRKVPMKIFPAVHYSMGGLYVDYDQMTNIKGLFAAGECDFSQHGGNRLGANSLLSAIYGGTVAGPNAIDYISNIDRSYTDMDESIFEKRKAEEQERFDKLLAMRGTENAYKLHRELGEIMTANVTVVRENEKLLETDKKIVELMKRYEDIDMEDTQTWSNQAVFFTRQLWNMLVLARVITIGAYNRNESRGAHYKPEFPERNDEEWLKTTMASFQGAFEKPQFTYDDVDVSLIPPRKRDYTSKSKGGKK
>NZ_CP020354.1|WP_000139712.1|1102464_1103280_+|succinate-dehydrogenase-iron-sulfur-subunit
MTEQSVKNTPQHETQSKPKQKTVKLIIKRQDTSDSKPYEETFEIPYRENLNVIACLMEIRRNPVNIKGEKTTPVVWDMNCLEEVCGACSMVINGRARQSCSAIVDQLEQPIRLEPMNTFPVIRDLQVDRSRMFDNLKRMKAWIPIDGTYDLGPGPRMPEKKRQTAYELSKCMTCGVCLEVCPNVTENNKFVGAQAISQVRLFNLHPTGSMTKDERLNALMGTGGLQQCGNSQNCVNACPKGIPLTTSIAAMNRETTFHMFKSFFGSDHEVE

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Crispr_ID: NZ_CP020354_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020354_3

1109793-1110036

Orphan

Consensus_repeat	Method
ACAATGCAAGTTGGCGGGG	CRT

4 spacers

The CRISPR arrays of NZ_CP020354_3

>merge|NZ_CP020354|3|1109793-1110036|CRT
ACAATGCAAGTTGGCGGGGCCCCAACATAGAGAAATTGGATCACCAATTTCAACAGACAATGCAAGTTGGCGGGGCCACAACAGAGAGAAATAGGATCACCAATTCCAACAAACAATGCAAGTTGGCGGGGGCCCCAACATAGAAGCTGGCGAAAAGTCAGCTTACAAAAATGTGCAAGTTGGCGGGGCCCCAACATAGAGAAATTGGAACCCCAATTTCTACAGACAATGCAAGTTGGGGTAG

>NZ_CP020354|3|2|1109793-1110036|CRT
ACAATGCAAGTTGGCGGGG	CCCCAACATAGAGAAATTGGATCACCAATTTCAACAG
ACAATGCAAGTTGGCGGGG	CCACAACAGAGAGAAATAGGATCACCAATTCCAACAA
ACAATGCAAGTTGGCGGGG	GCCCCAACATAGAAGCTGGCGAAAAGTCAGCTTACAAA
AATGTGCAAGTTGGCGGGG	CCCCAACATAGAGAAATTGGAACCCCAATTTCTACAG
ACAATGCAAGTTGGGGTAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020354.1\|WP_001802045.1\|1113449_1113674_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_001063559.1\|1114997_1115723_-\|superantigen-like-protein-SSL13	unknown	unknown	gnl\|CDD\|106307
NZ_CP020354.1\|WP_000765708.1\|1113346_1113493_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_000857483.1\|1111714_1112674_-\|beta-channel-forming-cytolysin	unknown	unknown	gnl\|CDD\|273388
NZ_CP020354.1\|WP_001791787.1\|1105538_1105706_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_000584398.1\|1107666_1108173_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_031775077.1\|1106546_1106618_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_000231632.1\|1111004_1111238_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_001032814.1\|1110197_1110383_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_000041896.1\|1114173_1114890_-\|superantigen-like-protein-SSL12	unknown	unknown	gnl\|CDD\|171995
NZ_CP020354.1\|WP_000739532.1\|1115817_1116543_-\|superantigen-like-protein-SSL14	unknown	unknown	gnl\|CDD\|171855
NZ_CP020354.1\|WP_000791580.1\|1108431_1108929_+\|complement-convertase-inhibitor-Efb	unknown	unknown	gnl\|CDD\|289007
NZ_CP020354.1\|WP_000739572.1\|1106598_1106994_-\|formyl-peptide-receptor	unknown	unknown	gnl\|CDD\|171849
NZ_CP020354.1\|WP_000793612.1\|1116980_1117982_+\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|235269
NZ_CP020354.1\|WP_000669537.1\|1109082_1109433_+\|complement-inhibitor-SCIN-B	unknown	unknown	gnl\|CDD\|371594
NZ_CP020354.1\|WP_000659319.1\|1104327_1104915_+\|XTP/dITP-diphosphatase	unknown	unknown	gnl\|CDD\|184835
NZ_CP020354.1\|WP_001039659.1\|1103515_1104316_+\|glutamate-racemase	unknown	unknown	gnl\|CDD\|234851
NZ_CP020354.1\|WP_000049484.1\|1104907_1105411_+\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|223695
NZ_CP020354.1\|WP_001074342.1\|1118004_1118937_+\|carbamate-kinase	unknown	unknown	gnl\|CDD\|237071
NZ_CP020354.1\|WP_000739210.1\|1105899_1106229_+\|complement-convertase-inhibitor-Ecb	unknown	unknown	gnl\|CDD\|289007

Protein	Function_ID	Function_description	E-value
NZ_CP020354.1\|WP_000793612.1\|1116980_1117982_+\|ornithine-carbamoyltransferase	gnl\|CDD\|235269	PRK04284, PRK04284, ornithine carbamoyltransferase; Provisional.	0
NZ_CP020354.1\|WP_001063559.1\|1114997_1115723_-\|superantigen-like-protein-SSL13	gnl\|CDD\|106307	PRK13349, PRK13349, superantigen-like protein; Reviewed.	1.29834e-148
NZ_CP020354.1\|WP_000857483.1\|1111714_1112674_-\|beta-channel-forming-cytolysin	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	4.27434e-141
NZ_CP020354.1\|WP_000041896.1\|1114173_1114890_-\|superantigen-like-protein-SSL12	gnl\|CDD\|171995	PRK13350, PRK13350, superantigen-like protein; Reviewed.	1.29441e-152
NZ_CP020354.1\|WP_000739532.1\|1115817_1116543_-\|superantigen-like-protein-SSL14	gnl\|CDD\|171855	PRK13043, PRK13043, superantigen-like protein; Reviewed.	4.17321e-162
NZ_CP020354.1\|WP_000791580.1\|1108431_1108929_+\|complement-convertase-inhibitor-Efb	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	5.38388e-27
NZ_CP020354.1\|WP_000739572.1\|1106598_1106994_-\|formyl-peptide-receptor	gnl\|CDD\|171849	PRK13033, PRK13033, formyl peptide receptor-like 1 inhibitory protein; Reviewed.	1.17946e-62
NZ_CP020354.1\|WP_000669537.1\|1109082_1109433_+\|complement-inhibitor-SCIN-B	gnl\|CDD\|371594	pfam11546, CompInhib_SCIN, Staphylococcal complement inhibitor SCIN. SCIN is released by Staphylococcus aureus to counteract the host immune defense. The protein binds to and inhibits C3 convertases on the bacterial surface, reducing phagocytosis and blocking downstream effector functions by C3b deposition on its surface. An 18 residue stretch 31-48 is crucial for SCIN activity.	2.0882e-48
NZ_CP020354.1\|WP_000659319.1\|1104327_1104915_+\|XTP/dITP-diphosphatase	gnl\|CDD\|184835	PRK14822, PRK14822, XTP/dITP diphosphatase.	6.07313e-114
NZ_CP020354.1\|WP_001039659.1\|1103515_1104316_+\|glutamate-racemase	gnl\|CDD\|234851	PRK00865, PRK00865, glutamate racemase; Provisional.	2.38427e-134
NZ_CP020354.1\|WP_000049484.1\|1104907_1105411_+\|metallophosphoesterase	gnl\|CDD\|223695	COG0622, COG0622, Predicted phosphoesterase [General function prediction only].	9.91823e-44
NZ_CP020354.1\|WP_001074342.1\|1118004_1118937_+\|carbamate-kinase	gnl\|CDD\|237071	PRK12353, PRK12353, putative amino acid kinase; Reviewed.	0
NZ_CP020354.1\|WP_000739210.1\|1105899_1106229_+\|complement-convertase-inhibitor-Ecb	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	2.22818e-21

>NZ_CP020354.1|WP_000669537.1|1109082_1109433_+|complement-inhibitor-SCIN-B
MKFKKYILTGTLALLLSSTGIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSNVYALAAGSLNPYYKRTIMMNEYRAKAALKKNDFVSMADAKVALEKIYKEIDEIINR
>NZ_CP020354.1|WP_000791580.1|1108431_1108929_+|complement-convertase-inhibitor-Efb
MKNKLIAKSLLTIAAIGITTTTIASTADASEGYGPREKKPVSINHNIVEYNDGTFKYQSRPKFNSTPKYIKFKHDYNILEFNDGTFEYGARPQFNKPAAKTDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVK
>NZ_CP020354.1|WP_000584398.1|1107666_1108173_+|hypothetical-protein
MIIKILTILLLLCILSYLVTNRKKPFLFLKTLFMGVVFIFIGYISLAISAVIIYGIIQFITIDFGSFFLMGIILILISSIFQLFIVRLLFRKKNVDLTEVVVLEHLIQWFLVYFAIYQAVNEKMDINDINIDNFQSVFFDVSNLNLVILPTLIISWVTIFNYRMRSYK
>NZ_CP020354.1|WP_000739572.1|1106598_1106994_-|formyl-peptide-receptor
MKKNITKVIIASTVIATGLLTHSNDAKAFFSYEWKGLEIAKKLADDEKKDEERADRLIKDAEKERTYTGKTVEDLYVIAKKLGKGNTIAVVRIIDGGKNGYYTFDITRPLEEHRKNIKVVAKGEIDSITWY
>NZ_CP020354.1|WP_031775077.1|1106546_1106618_-|hypothetical-protein
MRLLGIKKHTELNSCTPNVRKQC
>NZ_CP020354.1|WP_000739210.1|1105899_1106229_+|complement-convertase-inhibitor-Ecb
MKKNFIGKSILSIAAISLTVSTFAGESHAQTKNVEAAKKYDQYQTNFKKQVNKKVVDAQKAVNLFKRTRTVATHRKAQRAVNLIHFQHSYEKKKLQRQIDLVLKYNTLK
>NZ_CP020354.1|WP_001791787.1|1105538_1105706_+|hypothetical-protein
MKRIVILENVIVDNPIWLNHVDYLVKSVLLKSIKLRFQEVRKFEILVKIMNRIHI
>NZ_CP020354.1|WP_000049484.1|1104907_1105411_+|metallophosphoesterase
MSKWIIVSDNHTESGVLYQIYEMHPDADVYLHLGDSEFAYDDTELSLFNRVKGNCDFYPEFENEAVAKYNDVKAFYTHGHLYQVNRTRDLLAEKGLELGCLFAFYGHTHVAKYEYINGVHVINPGSISQSRSSMEETYAEVIIDDQTLHGTINFKNRHHETISHTTF
>NZ_CP020354.1|WP_000659319.1|1104327_1104915_+|XTP/dITP-diphosphatase
MKEIVIASNNQGKINDFKVIFPDYHVIGISELIPDFDVEETGSTFEENAILKSEAAAKALNKTVIADDSGLEVFALNGEPGIYSARYAGENKSDEANIEKLLNKLGNTTDRRAQFVCVISMSGPDMETKVFKGTVSGEIADGKYGENGFGYDPIFYVPKLDKTMAQLSKEQKGQISHRRNAINLLQAFLEGEKNV
>NZ_CP020354.1|WP_001039659.1|1103515_1104316_+|glutamate-racemase
MNKPIGVIDSGVGGLTVAKEIMRQLPNETIYYLGDIGRCPYGPRPGEQVKQYTVEIARKLMEFDIKMLVIACNTATAVALEYLQKTLSIPVIGVIEPGARTAIMTTRNQNVLVLGTEGTIKSEAYRTHIKRINPHVEVHGVACPGFVPLVEQMRYSDPTITSIVIHQTLKRWRNSESDTVILGCTHYPLLYKPIYDYFGGKKTVISSGLETAREVSALLTFSNEHASYTEHPDHRFFATGDPTHITNIIKEWLNLSVNVERISVND
>NZ_CP020354.1|WP_001032814.1|1110197_1110383_-|hypothetical-protein
MNKHINKKAAKLLEDYKKVQQRKSKETDRGCLKSVIMLIVLFFLIIFGIVACSTNVNFFFQ
>NZ_CP020354.1|WP_000231632.1|1111004_1111238_-|hypothetical-protein
MVFNDWEINVVYSGEHEVVTNEKSLFVIDEFYDVAIAIYYLDGKLKVAHVNYGSDFTIDVANKVFELNIQNPNVDEH
>NZ_CP020354.1|WP_000857483.1|1111714_1112674_-|beta-channel-forming-cytolysin
MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWIDRSSERYKIDWEKEEMTN
>NZ_CP020354.1|WP_000765708.1|1113346_1113493_+|hypothetical-protein
MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE
>NZ_CP020354.1|WP_001802045.1|1113449_1113674_+|hypothetical-protein
MLIQERGLKMTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYVSLKEH
>NZ_CP020354.1|WP_000041896.1|1114173_1114890_-|superantigen-like-protein-SSL12
MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHFSFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQLWWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAREALIKNKILYNENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD
>NZ_CP020354.1|WP_001063559.1|1114997_1115723_-|superantigen-like-protein-SSL13
MNNNITKKIILSTTLLLLGTASTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYLTFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDSFALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIRQTLIKSKKLYNNSYNKGQIKITGADNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKSN
>NZ_CP020354.1|WP_000739532.1|1115817_1116543_-|superantigen-like-protein-SSL14
MKKNIMNKLVLSTALLLLGTTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHFSLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEGYWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIRQTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPRNAEIEVILEKSN
>NZ_CP020354.1|WP_000793612.1|1116980_1117982_+|ornithine-carbamoyltransferase
MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDNIDQGVKGSDVIYTDVWVSMGEPDEVWKERLELLKPYQVNKEMMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVTDEVFESKASVVFQEAENRMHTIKAVMVATLGEF
>NZ_CP020354.1|WP_001074342.1|1118004_1118937_+|carbamate-kinase
MAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAALEGKVGTVIKK

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Crispr_ID: NZ_CP020354_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020354_4

1199711-1199796

Unclear

Consensus_repeat	Method
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020354_4

>merge|NZ_CP020354|4|1199711-1199796|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACATAGAAGCTGGCGGAAAGTCAGCTTACAATAATGTGCAAGTTGG

>NZ_CP020354|4|2|1199711-1199796|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CGGGGCCCCAACATAGAAGCTGGCGG
AAAGTCAGCTTACAATAATGTGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020354.1\|WP_000915244.1\|1199869_1202476_-\|YfhO-family-protein	unknown	unknown	gnl\|CDD\|226888
NZ_CP020354.1\|WP_001041667.1\|1206943_1208062_+\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|366664
NZ_CP020354.1\|WP_000195254.1\|1212783_1214091_+\|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO	unknown	unknown	gnl\|CDD\|235416
NZ_CP020354.1\|WP_000687328.1\|1198209_1198947_+\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	unknown	unknown	gnl\|CDD\|234581
NZ_CP020354.1\|WP_000531320.1\|1195083_1195416_+\|putative-DNA-binding-protein	unknown	unknown	gnl\|CDD\|234647
NZ_CP020354.1\|WP_000181404.1\|1199049_1199400_+\|50S-ribosomal-protein-L19	unknown	unknown	gnl\|CDD\|235418
NZ_CP020354.1\|WP_000863479.1\|1195441_1196809_+\|signal-recognition-particle-protein	unknown	unknown	gnl\|CDD\|236780
NZ_CP020354.1\|WP_106669533.1\|1190280_1193847_+\|chromosome-segregation-protein-SMC	unknown	unknown	gnl\|CDD\|224117
NZ_CP020354.1\|WP_000007687.1\|1193846_1195097_+\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
NZ_CP020354.1\|WP_000110251.1\|1205808_1206717_+\|succinate--CoA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|180194
NZ_CP020354.1\|WP_000236715.1\|1202876_1203761_+\|ribosome-biogenesis-GTPase-YlqF	unknown	unknown	gnl\|CDD\|236570
NZ_CP020354.1\|WP_001557331.1\|1210552_1212628_+\|type-I-DNA-topoisomerase	unknown	unknown	gnl\|CDD\|235516
NZ_CP020354.1\|WP_000672867.1\|1208089_1209334_+\|FemA/FemB-family-glycyltransferase-FmhC	unknown	unknown	gnl\|CDD\|367067
NZ_CP020354.1\|WP_000043237.1\|1189402_1190134_+\|ribonuclease-III	unknown	unknown	gnl\|CDD\|234633
NZ_CP020354.1\|WP_001020801.1\|1204620_1205787_+\|ADP-forming-succinate--CoA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234813
NZ_CP020354.1\|WP_000268754.1\|1197243_1197519_+\|30S-ribosomal-protein-S16	unknown	unknown	gnl\|CDD\|223306
NZ_CP020354.1\|WP_000593192.1\|1209506_1210379_+\|DNA-protecting-protein-DprA	unknown	unknown	gnl\|CDD\|223829
NZ_CP020354.1\|WP_001261987.1\|1197706_1198210_+\|ribosome-maturation-factor-RimM	unknown	unknown	gnl\|CDD\|234650
NZ_CP020354.1\|WP_000426914.1\|1189053_1189287_+\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|179197
NZ_CP020354.1\|WP_000176387.1\|1203744_1204512_+\|ribonuclease-HII	unknown	unknown	gnl\|CDD\|260003

Protein	Function_ID	Function_description	E-value
NZ_CP020354.1\|WP_000915244.1\|1199869_1202476_-\|YfhO-family-protein	gnl\|CDD\|226888	COG4485, COG4485, Predicted membrane protein [Function unknown].	0
NZ_CP020354.1\|WP_001041667.1\|1206943_1208062_+\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|366664	pfam01476, LysM, LysM domain. The LysM (lysin motif) domain is about 40 residues long. It is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. The structure of this domain is known.	1.58681e-14
NZ_CP020354.1\|WP_000195254.1\|1212783_1214091_+\|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO	gnl\|CDD\|235416	PRK05335, PRK05335, tRNA (uracil-5-)-methyltransferase Gid; Reviewed.	0
NZ_CP020354.1\|WP_000687328.1\|1198209_1198947_+\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	gnl\|CDD\|234581	PRK00026, trmD, tRNA (guanine-N(1)-)-methyltransferase; Reviewed.	2.98496e-164
NZ_CP020354.1\|WP_000531320.1\|1195083_1195416_+\|putative-DNA-binding-protein	gnl\|CDD\|234647	PRK00118, PRK00118, putative DNA-binding protein; Validated.	5.84113e-47
NZ_CP020354.1\|WP_000181404.1\|1199049_1199400_+\|50S-ribosomal-protein-L19	gnl\|CDD\|235418	PRK05338, rplS, 50S ribosomal protein L19; Provisional.	6.77895e-70
NZ_CP020354.1\|WP_000863479.1\|1195441_1196809_+\|signal-recognition-particle-protein	gnl\|CDD\|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0
NZ_CP020354.1\|WP_106669533.1\|1190280_1193847_+\|chromosome-segregation-protein-SMC	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	0
NZ_CP020354.1\|WP_000007687.1\|1193846_1195097_+\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	0
NZ_CP020354.1\|WP_000110251.1\|1205808_1206717_+\|succinate--CoA-ligase-subunit-alpha	gnl\|CDD\|180194	PRK05678, PRK05678, succinyl-CoA synthetase subunit alpha; Validated.	0
NZ_CP020354.1\|WP_000236715.1\|1202876_1203761_+\|ribosome-biogenesis-GTPase-YlqF	gnl\|CDD\|236570	PRK09563, rbgA, GTPase YlqF; Reviewed.	2.28339e-159
NZ_CP020354.1\|WP_001557331.1\|1210552_1212628_+\|type-I-DNA-topoisomerase	gnl\|CDD\|235516	PRK05582, PRK05582, type I DNA topoisomerase.	0
NZ_CP020354.1\|WP_000672867.1\|1208089_1209334_+\|FemA/FemB-family-glycyltransferase-FmhC	gnl\|CDD\|367067	pfam02388, FemAB, FemAB family. The femAB operon codes for two nearly identical approximately 50-kDa proteins involved in the formation of the Staphylococcal pentaglycine interpeptide bridge in peptidoglycan. These proteins are also considered as a factor influencing the level of methicillin resistance.	0
NZ_CP020354.1\|WP_000043237.1\|1189402_1190134_+\|ribonuclease-III	gnl\|CDD\|234633	PRK00102, rnc, ribonuclease III; Reviewed.	4.78039e-115
NZ_CP020354.1\|WP_001020801.1\|1204620_1205787_+\|ADP-forming-succinate--CoA-ligase-subunit-beta	gnl\|CDD\|234813	PRK00696, sucC, ADP-forming succinate--CoA ligase subunit beta.	0
NZ_CP020354.1\|WP_000268754.1\|1197243_1197519_+\|30S-ribosomal-protein-S16	gnl\|CDD\|223306	COG0228, RpsP, Ribosomal protein S16 [Translation, ribosomal structure and biogenesis].	3.01687e-41
NZ_CP020354.1\|WP_000593192.1\|1209506_1210379_+\|DNA-protecting-protein-DprA	gnl\|CDD\|223829	COG0758, Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion].	7.99896e-103
NZ_CP020354.1\|WP_001261987.1\|1197706_1198210_+\|ribosome-maturation-factor-RimM	gnl\|CDD\|234650	PRK00122, rimM, 16S rRNA-processing protein RimM; Provisional.	1.02289e-68
NZ_CP020354.1\|WP_000426914.1\|1189053_1189287_+\|acyl-carrier-protein	gnl\|CDD\|179197	PRK00982, acpP, acyl carrier protein; Provisional.	5.23888e-31
NZ_CP020354.1\|WP_000176387.1\|1203744_1204512_+\|ribonuclease-HII	gnl\|CDD\|260003	cd07182, RNase_HII_bacteria_HII_like, Bacterial Ribonuclease HII-like. This family includes mostly bacterial type 2 RNases H, with some eukaryotic members. Bacterial RNase HII has a role in primer removal based on its involvement in ribonucleotide-specific catalytic activity in the presence of RNA/DNA hybrid substrates. Several bacteria, such as Bacillus subtilis, have two different type II RNases H, RNases HII and HIII; double deletion of these leads to cellular lethality. It appears that type I and type II RNases H also have overlapping functions in cells, as over-expression of Escherichia coli RNase HII can complement an RNase HI deletion phenotype. In Leishmania mitochondria, of the four distinct RNase H genes (H1, HIIA, HIIB, HIIC), HIIC is essential for the survival of the parasite and thus can be a potential target for anti-leishmanial chemotherapy. Ribonuclease H (RNase H) is classified into two families, type I (prokaryotic RNase HI, eukaryotic RNase H1 and viral RNase H) and type II (prokaryotic RNase HII and HIII, and eukaryotic RNase H2). RNase H endonucleolytically hydrolyzes an RNA strand when it is annealed to a complementary DNA strand in the presence of divalent cations, in DNA replication and repair.	9.05801e-95

>NZ_CP020354.1|WP_000181404.1|1199049_1199400_+|50S-ribosomal-protein-L19
MTNHKLIEAVTKSQLRTDLPSFRPGDTLRVHVRIIEGTRERIQVFEGVVIKRRGGGVSETFTVRKISSGVGVERTFPLHTPKIEKIEVKRRGKVRRAKLYYLRSLRGKAARIQEIR
>NZ_CP020354.1|WP_000687328.1|1198209_1198947_+|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD
MKIDYLTLFPEMFDGVLNHSIMKRAQENNKLQINTVNFRDYAINKHNQVDDYPYGGGQGMVLKPEPVFNAMEDLDVTEQTRVILMCPQGEPFSHQKAVELSKADHIVFICGHYEGYDERIRTHLVTDEISMGDYVLTGGELPAMTMTDAIVRLIPGVLGNEQSHQDDSFSDGLLEFPQYTRPREFKGLTVPDVLLSGNHANIDAWRHEQKLIRTYNKRPDLIEKYPLTNADKQILERYKIGLKKG
>NZ_CP020354.1|WP_001261987.1|1197706_1198210_+|ribosome-maturation-factor-RimM
MRVEVGQIVNTHGIKGEIKVKSNSDFTDVRFQPGQVLTVVHNNNDLEYTVKSHRVHKGLHMLTFEGINNINDIEHLKGSSIYQERDHEDIVLEENEFYYSDIIGCTVFDDQETPIGRVINIFETGANDVWVIKGSKEYLIPYIADVVKEVDVENKKIIITPMEGLLD
>NZ_CP020354.1|WP_000268754.1|1197243_1197519_+|30S-ribosomal-protein-S16
MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQIGTYNPTSANAPEIKVDEALALKWLNDGAKPTDTVHNILSKEGIMKKFDEQKKAK
>NZ_CP020354.1|WP_000863479.1|1195441_1196809_+|signal-recognition-particle-protein
MAFEGLSERLQATMQKMRGKGKLTEADIKIMMREVRLALLEADVNFKVVKEFIKTVSERALGSDVMQSLTPGQQVIKIVQDELTQLMGGENTSINMSNKPPTVVMMVGLQGAGKTTTAGKLALLMRKKYNKKPMLVAADIYRPAAINQLQTVGKQIDIPVYSEGDQVKPQQIVTNALKHAKEEHLDFVIIDTAGRLHIDEALMNELKEVKDIAKPNEIMLVVDSMTGQDAVNVAESFDDQLDVTGVTLTKLDGDTRGGAALSIRSVTQKPIKFVGMSEKLDGLELFHPERMASRILGMGDVLSLIEKAQQDVDQEKAKDLEKKMRESSFTLDDFLEQLDQVKNLGPLDDIMKMIPGMNKMKGLDKLNMSEKQIDHIKAIIQSMTPAERNNPDTLNVSRKKRIAKGSGRSLQEVNRLMKQFNDMKKMMKQFTGGGKGKKGKRNQMQNMLKGMNLPF
>NZ_CP020354.1|WP_000531320.1|1195083_1195416_+|putative-DNA-binding-protein
MGQNDLVKTLRMNYLFDFYQSLLTNKQRNYLELFYLEDYSLSEIADTFNVSRQAVYDNIRRTGDLVEDYEKKLELYQKFEQRREIYDEMKQHLSNPEQIQRYIQQLEDLE
>NZ_CP020354.1|WP_000007687.1|1193846_1195097_+|signal-recognition-particle-docking-protein-FtsY
MSFFKRLKDKFATNKENEEVKSLTEEQGQDKLEDTHSEGSTQDVNDLAENAEVKKKPRKLSEADFDDDGLISIEDFEEIEAQKMGAKFKAGLEKSRQNFQEQLNNLIARYRKVDEDFFEALEEMLITADVGFNTVMTLTEELRMEAQRRNIQDTEDLREVIVEKIVEIYHQEDDNSEAMNLEDGRLNVILMVGVNGVGKTTTIGKLAYRYKMEGKKVMLAAGDTFRAGAIDQLKVWGERVGVDVISQSEGSDPAAVMYDAINAAKNKGVDILICDTAGRLQNKTNLMQELEKVKRVINRAVPDAPHEALLCLDATTGQNALSQARNFKEVTNVTGIVLTKLDGTAKGGIVLAIRNELHIPVKYVGLGEQLDDLQPFNPESYVYGLFADMIEQNEEITTVENDQIVTEEKDDNHGSK
>NZ_CP020354.1|WP_106669533.1|1190280_1193847_+|chromosome-segregation-protein-SMC
MVYLKSIDAIGFKSFADQTNVQFDKGVTAIVGPNGSGKSNITDAIKWVLGEQSAKSLRGSKMEDIIFSGAEHRKAQNYAEVQLRLDNHSKKLSVDENEVIVTRRLYRSGESEYYINNDRARLKDIADLFLDSGLGKEAYSIISQGRVDEILNAKPIDRRQIIEESAGVLKYKKRKAESLNKLDQTEDNLTRVEDILYDLEGRVEPLKEEAAIAKEYKTLSHQMKHSDIVVTVHDIDQYTNDNRQLDQRLNDLQGQQANKEADKQRLSQQIQQYKGKRHQLDNDVESLNYQLVKATEAFEKYTGQLNVLEERKKNQSETNARYEEEQENLMELLENISNEISEAQDTYKSLKSKQKELNAVIRELEEQLYVSDEAHDEKLEEIKNEYYTLMSEQSDVNNDIRFLKHTIEENEAKKSRLDSRLVEVFEQLKDIQGQIKTTKKEYQQTNKELSAVDKEIKNIEKDLTDTKKAQNEYEEKLYQAYRYTEKMKTRIDSLATQEEEYTYFFNGVKHILKAKNKELKGIHGAVAEIIDVPSKLTQAIETALGASLQHVIVDSEKDGRQAIQFLKERNLGRATFLPLNVIQSRVVATDIKSIAKEANGFISIASEAVKVAPEYQNIIGNLLGNTIIVDHLKHANELARAIKYRTRIVTLEGDIVNPGGSMTGGGARKSKSILSQKDELTTMRHQLEDYLRQTESFEQQFKELKIKSDQLSELYFEKSQKHNTLKEQVHHFEMELDRLTTQETQIKNDHEEFEFEKNDGYTSDKSRQTLSEKETHLESIKASLKRLEDEIERYTKLSKEGKESVTKTQQTLHQKQSDLAVVKERIKTQQQTIDRLNNQSQQTKHQLKDVKEKIAFFNSDEVMGEQAFQNIKDQINGQQETRTRLSDELDKLKQQRIELNEQIDAQEAKLQVCHQDILAIENHYQDIKAEQSKLDVLIHHAIDHLNDEYQLTVERAKSEYTSDESIDALRKKVKLMKMSIDELGPVNLNAIEQFEELNERYTFLSEQRTDLRKAKETLEQIISEMDQEVTERFKETFHAIQGHFTAVFKQLFGGGDAELQLTEADYLTAGIDIVVQPLGKKLQHLSLLSGGERALTAIALLFAILKVRSAPFVILDEVEAALDEANVIRYAKYLNELSDETQFIVITHRKGTMEFADRLYGVTMQESGVTKLVSVNLNTIDDVLKEEQ
>NZ_CP020354.1|WP_000043237.1|1189402_1190134_+|ribonuclease-III
MSKQKKSEIVNRFRKRFDTKMTELGFTYQNIDLYQQAFSHSSFINDFNMNRLDHNERLEFLGDAVLELTVSRYLFDKHPNLPEGNLTKMRATIVCEPSLVIFANKIGLNEMILLGKGEEKTGGRTRPSLISDAFEAFIGALYLDQGLDIVWKFAEKVIFPHVEQNELLGVVDFKTQFQEYVHQQNKGDVTYNLIKEEGPAHHRLFTSEVILQGEAIAEGKGKTKKESEQRAAESAYKQLKQIK
>NZ_CP020354.1|WP_000426914.1|1189053_1189287_+|acyl-carrier-protein
MENFDKVKDIIVDRLGVDADKVTEDASFKDDLGADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKFINSLEK
>NZ_CP020354.1|WP_000915244.1|1199869_1202476_-|YfhO-family-protein
MLKKWLNSNVKQFFVITFISVILTLILFSTHIYDYIVNGTVFSGAGDGFRQMMPFQMYLYEHLSSFSSLYDASFGLGGDYMKGLSYYYSLSPLMWLNFLFIKIGETVGIFNPTTIHFWPTNQLIMAMIRAIITFVVTFYLFKILHFKRSTNMIATILYGMSTVVIYFNFTWSFYGSLLYLLPLSILGLERYFQQRKIGIFIVAIALTLFSNFYFSYYQAIIIGCYYLYRLIFTYKYDIVSRTQKLICVISATVLSVLSSVFGLFTGISAFLENDRKQNPNVDIPFLTPLDYHYFFFSDGFYITISILTIVALLSFKLYRFYFYRLFAIVTWLLFIGSLSQYFDSAFNGFSFPERRWVYILALSSSALCGLFIQHLSTLNMKYYLIRTIPVSIIALLYVLLSPTHPLALIVGIILLMVLAVILKFSLWRYKKLTVAILVLIVMIQQIVILDNNKNMAIKPYQQSLSTLKQHDYHSNYVNQLIKKINQNATGPFNRIDYMSDYALNSPFIYHYNGISLYSSIFNGDILKYYDKTLQINMPIDKNSTYRLLGNRQNLLSLWNVNDRIRVNHDDNLPYGFKIKSEHKDNKVRWIHSKNTIHYPSAHITNKVFSNKELKSPLDKEQAMLQGIVSNKTKDVNTHFKANKNLLSDSTIKLNSAAWQSPTKHLLQVKQNNGGLTVQLPKSVSNQFKDLYFEMDLELLSPDKAHDVKVNEYTQERNKLTYKYRRFVTPVTIRIKASDRIRLSLPKGKYRVNLKGIYGEDYTTLKDASNSLEAVKVSKTKQGYTITKNKNSSGYIVLPTAYNQGMKATSGDQSLKVEQVNGVMTGIKAPKNITKIQLSYAPPYYYLLITITIFGIICSIIFTRWARQK
>NZ_CP020354.1|WP_000236715.1|1202876_1203761_+|ribosome-biogenesis-GTPase-YlqF
MVIQWYPGHMAKAKREVSEQLKKVDVVFELVDARIPYSSRNPMIDEVINQKPRVVILNKKDMSNLNEMSKWEQFFIDKGYYPVSVDAKHGKNLKKVEAAAIKATAEKFEREKAKGLKPRAIRAMIVGIPNVGKSTLINKLAKRSIAQTGNKPGVTKQQQWIKVGNALQLLDTPGILWPKFEDEEVGKKLSLTGAIKDSIVHLDEVAIYGLNFLIQHDLARLKSHYNIEVPEDAEIIAWFDAIGKKRGLIRRGNEIDYEAVIELIIYDIRNAKIGNYCFDIFKDMTEELANDANN
>NZ_CP020354.1|WP_000176387.1|1203744_1204512_+|ribonuclease-HII
MTLTIKEVKQLINAVNTIEELENHECFLDERKGVQNAIARRRKALEKEQALKEKYVEMTYFENEILKEHPNAIICGIDEVGRGPLAGPVVACATILNSNHNYLGLDDSKKVPVTKRLELNEALKNEVTAFAYGIATAEEIDEFNIYKATQIAMQRAIDGLSVQPTHLLIDAMTLDNALPQVSLIKGDARSVSIAAASIMAKVFRDDYMTQLSKDYPEYGFEKNAGYGTKQHLLAIDDIGIMKEHRKSFEPIKSLL
>NZ_CP020354.1|WP_001020801.1|1204620_1205787_+|ADP-forming-succinate--CoA-ligase-subunit-beta
MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKELNSDVYVVKAQIHAGGRGKAGGVKIAKSLSEVETYAKELLGKTLVTHQTGPEGKEIKRLYIEEGCAIQKEYYVGFVIDRATDQVTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQARRIAFNINIPKESVNKAAKFLLALYNVFIEKDCSIVEINPLVTTADGDVLALDAKINFDDNALFRHKDVVELRDLEEEDPKEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLDAGGSATREKVTEAFKIILGDENVKGIFVNIFGGIMKCDVIAEGIVEAVKEVDLTLPLVVRLEGTNVELGKKILKDSGLAIEPAATMAEGAQKIVKLVKEA
>NZ_CP020354.1|WP_000110251.1|1205808_1206717_+|succinate--CoA-ligase-subunit-alpha
MSVFIDKNTKVMVQGITGSTALFHTKQMLDYGTKIVAGVTPGKGGQVVEGVPVFNTVEEAKNETGATVSVIYVPAPFAADSILEAADADLDMVICITEHIPVLDMVKVKRYLQGRKTRLVGPNCPGVITADECKIGIMPGYIHKKGHVGVVSRSGTLTYEAVHQLTEEGIGQTTAVGIGGDPVNGTNFIDVLKAFNEDDETKAVVMIGEIGGTAEEEAAEWIKANMTKPVVGFIGGQTAPPGKRMGHAGAIISGGKGTAEEKIKTLNSCGVKTAATPSEIGSTLIEAAKEAGIYEALLTVNK
>NZ_CP020354.1|WP_001041667.1|1206943_1208062_+|LysM-peptidoglycan-binding-domain-containing-protein
MNKQQSKVRYSIRKVSIGILSISIGMFLALGMSNKAYADEIDKSKDFTRGYEQNVFAKSELNANKNTTKDKIKNEGAVKTSDTSLKLDNKSAISNGNEINQDIKISNTPKNSSQGNNLVINNNEPTKEIKIANLEAQNSNQKKTNKVTNNYFGYYSFREAPKTQIYTVKKGDTLSAIALKYKTTVSNIQNTNNIANPNLIFIGQKLKVPMTPLVEPKTKTVSSNNKSNSNSSTLNYLKTLENRGWDFDGSYGWQCFDLVNVYWNHLYGHGLKGYGAKDIPYANNFNSEAKIYHNTPTFKAEPGDLVVFSGRFGGGYGHTAIVLNGDYDGKLMKFQSLDQNWNNGGWRKAEVAHKVVHNYENDMIFIRPFKKA
>NZ_CP020354.1|WP_000672867.1|1208089_1209334_+|FemA/FemB-family-glycyltransferase-FmhC
MKFSTLSEEEFTNYTKKHFKHYTQSIELYNYRNKINHEAHIVGVKNDKNEVIAACLLTEARIFKFYKYFYSHRGPLLDYFDAKLVCYFFKELSKFIYKNRGVFILVDPYLIENLRDANGRIIKNYNNSVIVKMLGKIGYLHQGYTTGYSNKSQIRWISVLDLKDKDENQLLKEMEYQTRRNIKKTIEIGVKVEDLSIEETNRFYKLFQMAEEKHGFHFMNEDYFKRMQEIYKDKAMLKIACINLNEYQDKLKIQLLKIENEMMTVNRALNENPNSKKNKSKLNQLNMQLSSINNRISKTEELIFEDGPVLDLAAALFICTDDEVYYLSSGSNPKYNQYMGAYHLQWHMIKYAKSHNINRYNFYGITGVFSNEADDFGVQQFKKGFNAHVEELIGDFIKPVRPILYKFAKLIYKV
>NZ_CP020354.1|WP_000593192.1|1209506_1210379_+|DNA-protecting-protein-DprA
MIKLFLLKLYWAHFSTKQIHQFLMAYPNVIKEEGRKKDSYLCEWVNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYITYMDSEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQIALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHITIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI
>NZ_CP020354.1|WP_001557331.1|1210552_1212628_+|type-I-DNA-topoisomerase
MTLADNLVIVESPAKAKTIEKYLGKKYKVIASMGHVRDLPRSQMGVDTEDNYEPKYITIRGKGPVVKELKKHAKKAKNVFLASDPDREGEAIAWHLSKILELEDSKENRVVFNEITKDAVKESFKNPREIEMNLVDAQQARRILDRLVGYNISPVLWKKVKKGLSAGRVQSVALRLVIDRENEIRNFKPEEYWTIEGEFRYKKSKFNAKFLHYKNKPFKLKTKKDVEKITAALDGDQFEITNVTKKEKTRNPANPFTTSTLQQEAARKLNFKARKTMMVAQQLYEGIDLKKQGTIGLITYMRTDSTRISDTAKAEAKQYITDKYGESYTSKRKASGKQGDQDAHEAIRPSSTMRTPDDMKSFLTKDQYRLYKLIWERFVASQMAPAILDTVSLDITQGDIKFRANGQTIKFKGFMTLYVETKDDSDSEKENKLPKLEQGDKVTATQIEPAQHYTQPPPRYTEARLVKTLEELKIGRPSTYAPTIDTIQKRNYVKLESKRFVPTELGEIVHEQVKEYFPEIIDVEFTVNMETLLDKIAEGDITWRKVIDGFFSSFKQDVERAEEEMEKIEIKDEPAGEDCEVCGSPMVIKMGRYGKFMACSNFPDCRNTKAIVKSIGVKCPKCNDGDVVERKSKKNRVFYGCSKYPECDFISWDKPIGRDCPKCNQYLVENKKGKTTQVICSNCDYKEAAQK
>NZ_CP020354.1|WP_000195254.1|1212783_1214091_+|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO
MTQTVNVIGAGLAGSEAAYQLAERGIKVNLIEMRPVKQTPAHHTDKFAELVCSNSLRGNALTNGVGVLKEEMRRLNSIIIEAADKARVPAGGALAVDRHDFSGYITETLKNHENITVINEEINAIPDGYTIIATGPLTTETLAQEIVDITGKDQLYFYDAAAPIIEKESIDMDKVYLKSRYDKGEAAYLNCPMTEDEFNRFYDAVLEAEVAPVNSFEKEKYFEGCMPFEVMAERGRKTLLFGPMKPVGLEDPKTGKRPYAVVQLRQDDAAGTLYNIVGFQTHLKWGAQKEVIKLIPGLENVDIVRYGVMHRNTFINSPDVLNEKYELISQPNIQFAGQMTGVEGYVESAASGLVAGINLAHKILGKGEVVFPRETMIGSMAYYISHAKNNKNFQPMNANFGLLPSLETRIKDKKERYEAQANRALDYLENFKKTL

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Crispr_ID: NZ_CP020354_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020354_5

1913363-1913447

Orphan

Consensus_repeat	Method
TGTTGGGTCCCACACCCCAACTTGCA	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of NZ_CP020354_5

>merge|NZ_CP020354|5|1913363-1913447|CRISPRCasFinder
TGTTGGGTCCCACACCCCAACTTGCATTGCCTGTAGAATTTCTTTTTTGAAATTCTCTATGTTGGGGCCCACACCCCAACTTGCA

>NZ_CP020354|5|3|1913363-1913447|CRISPRCasFinder
TGTTGGGTCCCACACCCCAACTTGCA	TTGCCTGTAGAATTTCTTTTTTGAAATTCTCTA
TGTTGGGGCCCACACCCCAACTTGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020354.1\|WP_000636142.1\|1912365_1913124_-\|type-I-methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|235576
NZ_CP020354.1\|WP_000544966.1\|1915769_1916501_-\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
NZ_CP020354.1\|WP_001250329.1\|1916502_1917816_-\|Mur-ligase-family-protein	unknown	unknown	gnl\|CDD\|223840
NZ_CP020354.1\|WP_001566709.1\|1915130_1915544_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_000949467.1\|1918107_1918608_+\|H-type-ferritin-FtnA	unknown	unknown	gnl\|CDD\|224445
NZ_CP020354.1\|WP_000153535.1\|1909387_1910017_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP020354.1\|WP_000613738.1\|1918997_1919552_+\|3'-5'-exonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
NZ_CP020354.1\|WP_000037079.1\|1908058_1909276_+\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214
NZ_CP020354.1\|WP_000428172.1\|1907505_1907781_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_001110179.1\|1911762_1912149_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_001147870.1\|1921635_1922997_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|225174
NZ_CP020354.1\|WP_001017131.1\|1910006_1911050_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
NZ_CP020354.1\|WP_000149064.1\|1911046_1911748_-\|cell-wall-active-antibiotics-response-protein	unknown	unknown	gnl\|CDD\|227100
NZ_CP020354.1\|WP_001790679.1\|1918689_1918782_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_000999713.1\|1913713_1914700_+\|aromatic-acid-exporter-family-protein	unknown	unknown	gnl\|CDD\|226614
NZ_CP020354.1\|WP_001789555.1\|1905428_1906685_-\|aminopeptidase	unknown	unknown	gnl\|CDD\|376723
NZ_CP020354.1\|WP_000140176.1\|1919618_1920689_-\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
NZ_CP020354.1\|WP_000228666.1\|1907034_1907499_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|319971
NZ_CP020354.1\|WP_000180460.1\|1906687_1906888_-\|DUF1128-family-protein	unknown	unknown	gnl\|CDD\|227177
NZ_CP020354.1\|WP_000548781.1\|1920935_1921466_-\|DUF3267-domain-containing-protein	unknown	unknown	gnl\|CDD\|378690

Protein	Function_ID	Function_description	E-value
NZ_CP020354.1\|WP_000636142.1\|1912365_1913124_-\|type-I-methionyl-aminopeptidase	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	1.9498e-126
NZ_CP020354.1\|WP_000544966.1\|1915769_1916501_-\|type-1-glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	1.99932e-120
NZ_CP020354.1\|WP_001250329.1\|1916502_1917816_-\|Mur-ligase-family-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	3.37755e-99
NZ_CP020354.1\|WP_000949467.1\|1918107_1918608_+\|H-type-ferritin-FtnA	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	4.6035e-74
NZ_CP020354.1\|WP_000153535.1\|1909387_1910017_-\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.75115e-79
NZ_CP020354.1\|WP_000613738.1\|1918997_1919552_+\|3'-5'-exonuclease	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	4.39188e-75
NZ_CP020354.1\|WP_000037079.1\|1908058_1909276_+\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	3.59491e-85
NZ_CP020354.1\|WP_001147870.1\|1921635_1922997_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	0
NZ_CP020354.1\|WP_001017131.1\|1910006_1911050_-\|sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	6.78722e-72
NZ_CP020354.1\|WP_000149064.1\|1911046_1911748_-\|cell-wall-active-antibiotics-response-protein	gnl\|CDD\|227100	COG4758, COG4758, Predicted membrane protein [Function unknown].	9.42019e-79
NZ_CP020354.1\|WP_000999713.1\|1913713_1914700_+\|aromatic-acid-exporter-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	6.20478e-76
NZ_CP020354.1\|WP_001789555.1\|1905428_1906685_-\|aminopeptidase	gnl\|CDD\|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
NZ_CP020354.1\|WP_000140176.1\|1919618_1920689_-\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
NZ_CP020354.1\|WP_000228666.1\|1907034_1907499_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	3.39151e-65
NZ_CP020354.1\|WP_000180460.1\|1906687_1906888_-\|DUF1128-family-protein	gnl\|CDD\|227177	COG4840, COG4840, Uncharacterized protein conserved in bacteria [Function unknown].	9.24488e-25
NZ_CP020354.1\|WP_000548781.1\|1920935_1921466_-\|DUF3267-domain-containing-protein	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.4991e-11

>NZ_CP020354.1|WP_000636142.1|1912365_1913124_-|type-I-methionyl-aminopeptidase
MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE
>NZ_CP020354.1|WP_001110179.1|1911762_1912149_-|hypothetical-protein
MNYVERYIEQFLRATVRNNIKHYLLMLDEKMKNLDDYMRYLITKKEQLSKLIDSLMLTLENKYIDIAEAFQIQCAREINNQEIENIKSELNKVEAYYAQIETQIQQTSTEKIATEKTSYLINYMNAVA
>NZ_CP020354.1|WP_000149064.1|1911046_1911748_-|cell-wall-active-antibiotics-response-protein
MTHKYISTQMLIIFTALMIIANFYYIFFEKIGFLLVLLLGCVLVYVGYLYFHKIRGLLAFWIGALLIAFTLLSNKYTIIILFVFLLLLIVRYLIHKFKPKKVVATDEVMTSPSFIKQKWFGEQRTPVYVYKWEDVQIQHGIGDLHIDLTKAANIKENNTIVVRHILGKVQVILPVNYNINLHVAAFYGSTYVNEKSYKVENNNIHIEEMMKPDNYTVNIYVSTFIGDVEVIYR
>NZ_CP020354.1|WP_001017131.1|1910006_1911050_-|sensor-histidine-kinase
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVSQQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGATFHIVSLPDSGTRIEVKAPLNKEDSYDD
>NZ_CP020354.1|WP_000153535.1|1909387_1910017_-|response-regulator-transcription-factor
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIAKGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
>NZ_CP020354.1|WP_000037079.1|1908058_1909276_+|YihY/virulence-factor-BrkB-family-protein
MSKKDHSSSKYLNSVKEAQEESKKKNKSNPKIDVDRTYIEPQQFQSKKPKKDDQVFFLSRLNKPAKYKKDSNFLSYLIYRIGKDDASGLAAQMTYHFVLAMFPMLLFLLTLLPFFNIKQSQITNMLSNAPAETSTLIKSVIGDITQNSSGGLLSIGLILAIWSASNGMTAIMNSFNVAYDVEDSRNGIVLKLLSVVFTVVMGVVFVVALALPTLGSVISHFLFGPLGFDEQVKWIFNLIRIVLPIIIIFIVFIVLYSVAPNVKTKLKSVLPGAVFTSIIWLAGSFGFGWYISNFGNYSKTYGSIAGIIILLLWLYITSFIIIVGAEINAIIHQRSVIKGKTPEEAALEHDDNNKNHYNENTRYEYDEDSNATHQRTYHVDEHPSDTYPEDDKNIKDKIVDKLKKD
>NZ_CP020354.1|WP_000428172.1|1907505_1907781_+|hypothetical-protein
MENKFVPGILIGAVIGGAISLADKSTRQALVQSVKDAKNGNRTRKPSKVSKIKDEVLYWKDVVEEIRRNNPELERSLKDAKETFVNRKNQR
>NZ_CP020354.1|WP_000228666.1|1907034_1907499_+|low-molecular-weight-phosphotyrosine-protein-phosphatase
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
>NZ_CP020354.1|WP_000180460.1|1906687_1906888_-|DUF1128-family-protein
MTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHD
>NZ_CP020354.1|WP_001789555.1|1905428_1906685_-|aminopeptidase
MGILTNYKEKLQQYAELLVKVGMNVQPKQPVFIRSSVETLELTHLIVEEAYHCGASDVRVVYSDPTLKRLKFENESVEHFANHELKSYDVEARMDYVKRGAANLALISEDPDLMDGIDSQKLQAFQQQNARAFKGYMESVQKNQFPWVVAAFPSKAWAKRVYPELSVEEAYIKFIDEVFDIVRIDGNDPVENWRQHIANLSVYAQKLQQKNYHALHYVSEGTDLTVGLAKNHIWEDATSYVNGKEQAFIANIPTEEVFTAPDRNRVDGYVTNKLPLSYNGTIIDQFKLMFKDGEIIDFSAEKGEAVLKDLINTDEGSRRLGEVALVPDDSPISNRNTIFYNTLFDENAACHLAIGSAYAFNIQGGTEMTVEEKIASGLNDSNVHVDFMIGSSDLTIYGIFEDGSKELVFENGNWASTF
>NZ_CP020354.1|WP_000999713.1|1913713_1914700_+|aromatic-acid-exporter-family-protein
MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA
>NZ_CP020354.1|WP_001566709.1|1915130_1915544_-|hypothetical-protein
MKPTKVILKDASYLHSKTSITFILKDVVIEEDNKIYYFDTSATFEDQEVKFEFALFDSDMDNLKHMDYDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDSGLRHSNMATESGISLRINVAKSDFTKFINELASLH
>NZ_CP020354.1|WP_000544966.1|1915769_1916501_-|type-1-glutamine-amidotransferase
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIIIESDTFGTIVGFENHGGRTYHDFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEIQAKQVLIDRANRQKKSR
>NZ_CP020354.1|WP_001250329.1|1916502_1917816_-|Mur-ligase-family-protein
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISSFDVAPFLHLNINDEKYDMKIAGDFNAYNALAAYSVLRELGLNEQTIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>NZ_CP020354.1|WP_000949467.1|1918107_1918608_+|H-type-ferritin-FtnA
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEESMFETHINYLTRIGDDSNALYLYEKELGARTFDEE
>NZ_CP020354.1|WP_001790679.1|1918689_1918782_-|hypothetical-protein
MTKNTIISLENEKTQINDSENESSDLRKAK
>NZ_CP020354.1|WP_000613738.1|1918997_1919552_+|3'-5'-exonuclease
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKVHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>NZ_CP020354.1|WP_000140176.1|1919618_1920689_-|DNA-polymerase-IV
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>NZ_CP020354.1|WP_000548781.1|1920935_1921466_-|DUF3267-domain-containing-protein
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKWQFSIIMLSPLILLSTGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ
>NZ_CP020354.1|WP_001147870.1|1921635_1922997_-|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMESCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWSQKNAVVEKILDAFPNVTSIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGTIGLYMAPHAKHVYGVEVVPSAIEDAQQNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPATQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK

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Crispr_ID: NZ_CP020354_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020354_6

1989978-1990066

Orphan

Consensus_repeat	Method
GTTTTTGACTGACTTCTCAATCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP020354_6

>merge|NZ_CP020354|6|1989978-1990066|CRISPRCasFinder
GTTTTTGACTGACTTCTCAATCAATTTATAACTTTATTATACATAATCGTTTTTCTTTTGCAATAGTTTTTCGACTGACTTCTCAATCA

>NZ_CP020354|6|4|1989978-1990066|CRISPRCasFinder
GTTTTTGACTGACTTCTCAATCA	ATTTATAACTTTATTATACATAATCGTTTTTCTTTTGCAATAG
TTTTTCGACTGACTTCTCAATCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020354.1\|WP_072466816.1\|1984759_1985401_-\|pathogenicity-island-protein	unknown	unknown	gnl\|CDD\|374630
NZ_CP020354.1\|WP_000356927.1\|1985397_1985778_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_000179346.1\|1990820_1991993_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP020354.1\|WP_001058492.1\|1989074_1989284_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_000153640.1\|1989741_1989960_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NZ_CP020354.1\|WP_000708434.1\|1989276_1989423_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_000197635.1\|1994213_1994957_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP020354.1\|WP_033842989.1\|1986107_1987808_-\|DUF927-domain-containing-protein	unknown	unknown	gnl\|CDD\|227806
NZ_CP020354.1\|WP_000620857.1\|1990132_1990807_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188
NZ_CP020354.1\|WP_033842991.1\|1987821_1988691_-\|mobile-element-associated-protein	unknown	unknown	gnl\|CDD\|214926
NZ_CP020354.1\|WP_001103939.1\|1988754_1989072_-\|DUF1474-family-protein	unknown	unknown	gnl\|CDD\|369323
NZ_CP020354.1\|WP_001288441.1\|1983705_1984050_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_000867939.1\|1997385_1998171_+\|carbon-nitrogen-family-hydrolase	unknown	unknown	gnl\|CDD\|143607
NZ_CP020354.1\|WP_000522384.1\|1996398_1997025_+\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|226090
NZ_CP020354.1\|WP_001549197.1\|1998770_1998905_-\|delta-lysin-family-phenol-soluble-modulin	unknown	unknown	gnl\|CDD\|173213
NZ_CP020354.1\|WP_000917289.1\|1993753_1994038_-\|co-chaperone-GroES	unknown	unknown	gnl\|CDD\|178988
NZ_CP020354.1\|WP_001105707.1\|1999140_1999710_+\|accessory-gene-regulator-AgrB	unknown	unknown	gnl\|CDD\|214819
NZ_CP020354.1\|WP_000481967.1\|1989419_1989737_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|200128
NZ_CP020354.1\|WP_000240642.1\|1992061_1993678_-\|chaperonin-GroEL	unknown	unknown	gnl\|CDD\|234573
NZ_CP020354.1\|WP_049318078.1\|1994981_1996202_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236768

Protein	Function_ID	Function_description	E-value
NZ_CP020354.1\|WP_072466816.1\|1984759_1985401_-\|pathogenicity-island-protein	gnl\|CDD\|374630	pfam16560, SAPI, Putative mobile pathogenicity island. SAPI is a family of putative Gram-positive mobile pathogenicity island proteins. SAPIs are responsible for many superantigen-related diseases in humans as they carry two or more superantigens.	8.74157e-114
NZ_CP020354.1\|WP_033842989.1\|1986107_1987808_-\|DUF927-domain-containing-protein	gnl\|CDD\|227806	COG5519, COG5519, Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair].	4.04614e-166
NZ_CP020354.1\|WP_000179346.1\|1990820_1991993_+\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	4.55725e-47
NZ_CP020354.1\|WP_000240642.1\|1992061_1993678_-\|chaperonin-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NZ_CP020354.1\|WP_000153640.1\|1989741_1989960_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	9.85461e-11
NZ_CP020354.1\|WP_001549197.1\|1998770_1998905_-\|delta-lysin-family-phenol-soluble-modulin	gnl\|CDD\|173213	PRK14752, PRK14752, delta-lysin family phenol-soluble modulin.	8.25732e-15
NZ_CP020354.1\|WP_000197635.1\|1994213_1994957_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.67124e-11
NZ_CP020354.1\|WP_000620857.1\|1990132_1990807_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.58614e-10
NZ_CP020354.1\|WP_033842991.1\|1987821_1988691_-\|mobile-element-associated-protein	gnl\|CDD\|214926	smart00942, PriCT_1, Primase C terminal 1 (PriCT-1). This alpha helical domain is found at the C terminal of primases.	3.664e-15
NZ_CP020354.1\|WP_001103939.1\|1988754_1989072_-\|DUF1474-family-protein	gnl\|CDD\|369323	pfam07342, DUF1474, Protein of unknown function (DUF1474). This family consists of several bacterial proteins of around 100 residues in length. Members of this family seem to be found exclusively in Staphylococcus aureus. The function of this family is unknown.	1.54728e-20
NZ_CP020354.1\|WP_000522384.1\|1996398_1997025_+\|nitroreductase-family-protein	gnl\|CDD\|226090	COG3560, FMR2, Predicted oxidoreductase related to nitroreductase [General function prediction only].	5.71771e-116
NZ_CP020354.1\|WP_000917289.1\|1993753_1994038_-\|co-chaperone-GroES	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	5.94304e-45
NZ_CP020354.1\|WP_001105707.1\|1999140_1999710_+\|accessory-gene-regulator-AgrB	gnl\|CDD\|214819	smart00793, AgrB, Accessory gene regulator B. The accessory gene regulator (agr) of Staphylococcus aureus is the central regulatory system that controls the gene expression for a large set of virulence factors. The arg locus consists of two transcripts: RNAII and RNAIII. RNAII encodes four genes (agrA, B, C, and D) whose gene products assemble a quorum sensing system. At low cell density, the agr genes are continuously expressed at basal levels. A signal molecule, autoinducing peptide (AIP), produced and secreted by the bacteria, accumulates outside of the cells. When the cell density increases and the AIP concentration reaches a threshold, it activates the agr response, i.e. activation of secreted protein gene expression and subsequent repression of cell wall-associated protein genes. AgrB and AgrD are essential for the production of the autoinducing peptide which functions as a signal for quorum sensing. AgrB is a transmembrane protein. AgrB is involved in the proteolytic processing of AgrD and may have both proteolytic enzyme activity and a transporter facilitating the export of the processed AgrD peptide.	4.40383e-47
NZ_CP020354.1\|WP_000481967.1\|1989419_1989737_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|200128	TIGR01764, Probable_excisionase, DNA binding domain, excisionase family. An excisionase, or Xis protein, is a small protein that binds and promotes excisive recombination; it is not enzymatically active. This model represents a number of putative excisionases and related proteins from temperate phage, plasmids, and transposons, as well as DNA binding domains of other proteins, such as a DNA modification methylase. This model identifies mostly small proteins and N-terminal regions of large proteins, but some proteins appear to have two copies. This domain appears similar, in both sequence and predicted secondary structure (PSIPRED) to the MerR family of transcriptional regulators (pfam00376). [Unknown function, General].	5.89089e-17
NZ_CP020354.1\|WP_000867939.1\|1997385_1998171_+\|carbon-nitrogen-family-hydrolase	gnl\|CDD\|143607	cd07583, nitrilase_5, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	5.27649e-127
NZ_CP020354.1\|WP_049318078.1\|1994981_1996202_-\|hypothetical-protein	gnl\|CDD\|236768	PRK10819, PRK10819, transport protein TonB; Provisional.	2.22966e-09

>NZ_CP020354.1|WP_000153640.1|1989741_1989960_-|helix-turn-helix-transcriptional-regulator
MTILANTRKFKEAMFLKGFNLSDLSRETGVGISYLSQIINGKKIPSPKLAKKMAEVLQVEVNELFEFEVKEA
>NZ_CP020354.1|WP_000481967.1|1989419_1989737_-|helix-turn-helix-domain-containing-protein
MFNINIDEDEARELLEQAINARVDELAKEKYFMTYKELSNYLNLSKPTIEELLINNGMKYYMVGSTYRFKKSDVDEFMEQLTAHMNIQNNDFKQVNIKKLLEARQ
>NZ_CP020354.1|WP_000708434.1|1989276_1989423_-|hypothetical-protein
MKIYLTYICLVSLLTILLLAISNMYVAFSVYAWLITLGCNLTGGLENE
>NZ_CP020354.1|WP_001058492.1|1989074_1989284_-|hypothetical-protein
MNNEQKEVIEHVVYQLELSVMNNLESYEHTEYVNGIEVVSEISREKHLELIMKWCAQELKNNFQLEKGE
>NZ_CP020354.1|WP_001103939.1|1988754_1989072_-|DUF1474-family-protein
MNWEIKDLMCDIEVIKQKINDVATKHAWFVEDRFVKNELETKREHINFSASYLEHRIQNEHTVELLHVYLKEFGELIQKFHEIEKASSENFGEVSDDAQKLKITE
>NZ_CP020354.1|WP_033842991.1|1987821_1988691_-|mobile-element-associated-protein
MNEIKLEYDTHVSVVHYESLDSRSFNSFSKINWSKLVNKLSVPIEANYKYARGVAVYGDIKNGANDHGEIIKKHRNDKNVIYRDVIVLDYDEINDLKQLHEAISSALSNVAWFWHTSYSHRTEQARIRLYIPLNERISADDYRNYTKVLANKIGHKVDEGSYQPSRCFALPVIQKGHIFIKRVNDCPIMNADMLEQWSKEFEQSNASPNIKGYTRHDSAYWRELSFGTTEGNRNNALASLVGHLLRCRVNDYIVYSYALLWGQFACKPPMKEQEINATFQSILNKHYNN
>NZ_CP020354.1|WP_033842989.1|1986107_1987808_-|DUF927-domain-containing-protein
METGKSDVLDKIEKINKKDSALQEIIPKGYEIEHHQCGVALYQLIPSKKEGEPDKKVFITNTIPQITERFEDIESNEVSFNMLFYDNKTPVNIAVSAEEISDSRQLLKLVNKKLDVTSSTSTKLVDYINVSKRYNPPLNVKVATRLGHVKGYFIYPYQEVMKDSNIKLFSNDKGFQKLIDSFQSKGTLEGYSKKVFGQIKDLPMVMVMLYASLGSVLLREFGLQPFIVEISGSTSTGKTFTLNLVSSVWGTSDLITTWSSTQNSIESMASFLNSFPMFKDDTRNTHPKFVTSATYNFSSGESKSRSNINLTLNAKKEWRNILISTGESSIANMADEKAGVSARVVTLQDQPYPDNFDFTTLDKSFRENYGTLGLAFIKQYESKKDVYKNAFESYQRYFNQKGSNEIMQRLGRAFALLQVTGEVLNDIDGFEHDHFKIIEQAYDSMVKNNKTIDKPKQLLEELLQYLDANRNNIAGDGYSSVKNGDTKAIYKRDYLCILGQTVYDKLGHEMQTITGQWDKKGYLITSKDRIQKEVRFNSQKNRGYAIKDEIIKELGFDFSNSHNPYN
>NZ_CP020354.1|WP_000356927.1|1985397_1985778_-|hypothetical-protein
MDKEQLKKYIYDYVKEYKEIPIYQLEDLFKEINHDYIGRTSITHDKDENVVFWSGWNKITMFALIELVKSEQLDLVYRGSFVMRYLLDGRVPNLPLAICYPEDGQQTDVLSWVPMVLRINKEEKIK
>NZ_CP020354.1|WP_072466816.1|1984759_1985401_-|pathogenicity-island-protein
MNIETIVNEFETRAGTLLRYYTGLLEHSKVQPYCFKLYNDPFDMVYVMMNGKLFGHVYIKDCKVRQSFELASPKHTEGLIRSIEGHYVGYELHDGKQLSISDMMASQLFEDEYFMYGLETYAESNNSDVFEYLENGFDTDTLEGIQSSNTDVISNIEMLYQIATGINEPEPELVEGLKLVTEFVQDENATQEDYKALERKLNDLKASYYSLSK
>NZ_CP020354.1|WP_001288441.1|1983705_1984050_-|hypothetical-protein
MSEFEVKEKTYNLPNEHRQVLNVIRNTSNKYITKTKLLNQLGYEVNKANNRWLTQVITSLIINYHYPIGYSYKKDTRGYYIIKTQADKIEAIKSIKGLIEGSQNRLKALEEIEV
>NZ_CP020354.1|WP_000620857.1|1990132_1990807_+|helix-turn-helix-transcriptional-regulator
MIRNRLSELLSERGLKISRVAKDVKIARSSLTSMAQNDSEMIRYDAIDKLCSYLHISPSEFFEHNPINFDFTFDEEPNYKINDVFEGFEVTANITHAFSIENFDFEILVDVELDNRQKLNFDLDVSYKETEKITNSQHRFIFTIKNEDENIGLKKYVDSLSAGLKNLLFKKINQKLSGYVSEIIVKNIDDIEELFPNKGEKSTTLHKEILQTDSRLSSDIFKEY
>NZ_CP020354.1|WP_000179346.1|1990820_1991993_+|site-specific-integrase
MASYEKRGNTWRYRISLGKDAETGKYKYISNSGFKRKSDAKHHAEMVERQLRNGDYIAPSTSTFKQVADDWISQYANEVKVSSVRAREKAINHAIERFNNKPIQTINKHEYQRFVNDISAQYSKNYVDSIIASTNMIFKYAYDMKLIRIMPSEGIKRPKKKISVEELEDTEIHKKFLEKDELFQFLEVAKNHHSPQNSFEVFCTLAYTGMRAGELLALKWSDIDFENNTINITKTYYNPNNNKKQFQILTPKTESSIGKISVDPHVIKLLKNYKVDVQDTWKNELYVDNNFVFTDVNGYPLVIKKLQLWIKAILKKTDITNKQISTHSFRHTHCALLIEAGVHIKEIQERLRHKDINTTMNIYAKITNSYKKDASQKFSKLMENVSKDLF
>NZ_CP020354.1|WP_000240642.1|1992061_1993678_-|chaperonin-GroEL
MVKQLKFSEDARQAMLRGVDQLANAVKVTIGPKGRNVVLDKEFTAPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGLRQGIDKAVKVAVEALHENSQKVENKNEIAQVGAISAADEEIGRYISEAMEKVGNDGVITIEESNGLNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYILVTDKKISSFQDILPLLEQVVQSNRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGAQVITDDLGLDLKDASIDMLGTASKVEVTKDNTTVVDGDGDENSIDARVSQLKSQIEETESDFDREKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVNVYQKVSEIEAEGDIETGVNIVLKALTAPVRQIAENAGLEGSVIVERLKNAEPGVGFNAATNEWVNMLEAGIVDPTKVTRSALQHAASVAAMFLTTEAVVASIPEKNNDQPNMGGMPGMM
>NZ_CP020354.1|WP_000917289.1|1993753_1994038_-|co-chaperone-GroES
MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGTGRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
>NZ_CP020354.1|WP_000197635.1|1994213_1994957_+|CPBP-family-intramembrane-metalloprotease
MTRLWASLLTVIIYILSQFLPLLIVKKLPFVQYSGIELTKAVIYIQLVLFLIAATTIILINLKIKNPTKLELEVKEPKKYIIPWALLGFALVMIYQMVVSIVLTQIYGGQQVSPNTEKLIIIARKIPIFIFFVSIIGPLLEEYVFRKVIFGELFNAIKGNRIVAFIIATTVSSLIFALAHNDFKFIPVYFGMGVIFSLAYVWTKRLAVPIIIHMLQNGFVVIFQLLNPEALKKATEQANFIYHIFIP
>NZ_CP020354.1|WP_049318078.1|1994981_1996202_-|hypothetical-protein
MSYHWFKKMLLSTSILILSSSSLGLATHTVEAKDNLNGEKPTTNLNHNITSPSVNSEMNNNETGTPHESNQTGNEGTGSNSRDANPDSNNVKPDSNNQNPSPDSKPDPNNQNPSPNPKPDPDKPKPNPDPKPDPDNPKPNPDPKPDPDKPKPNPDPKPDPDKPKPNPNPKPDPNKPNPNPSPDPDQPGDSNHSGGSKNGGTWHPNASDGSNQGQWQPNGNQGNSQNPTGNDFVSQRFLALANGAYKYNPYILNQINKLGKDYGEVTDEDIYNIIRKQNFSGNAYLNGLQQQSNYFRFQYFNPLKSERYYRNLDEQVLALITGEIGSMPDLKKPEDKPDSKQRSFEPHEKDDFSVVKKQEDNKKSASTAYSKSWLAIVCSMMVVFSIMLFLFVKRNKKKNKNESQRR
>NZ_CP020354.1|WP_000522384.1|1996398_1997025_+|nitroreductase-family-protein
MGLFKKDKKAMTFDNAMEERRSIYNLKDSISISDDELESMIAHAVKHVPSSFNSQSTRIVLLLNDNNNKFWDNTKAILKEVMGENRDFEPTEQKIDNFKHSYGTILFYEDQDVVSGLQEQMPNYYDNFAIWSTQTNAMHQFAIWTALATKGIGASLQHYNPLVDEMTSNEFNIPKSWKLIAQMPFGDIREAAGEKTFNPVEDRFVIKK
>NZ_CP020354.1|WP_000867939.1|1997385_1998171_+|carbon-nitrogen-family-hydrolase
MKVQIYQLPIIFGDSSKNEAQITQWFEKNMNAEIDVVVLPEMWNNGYDLEHLNEKADNNLGQSFSFIKHLAEKYKVDIVAGSVSNIRNNQIFNTAFSVNKSGQLINEYDKVHLVPMLREHEFLTAGENVAEPFQLSDGTYVTQLICYDLRFPELLRYPARSGAKIAFYVAQWPMSRLHHWHSLLKARAIENNMFVIGTNSTGFDGNTEYAGHSIVINPNGDLVGELNESADILTVDLNLNEVEQQRENIPVFKSIKLDLYK
>NZ_CP020354.1|WP_001549197.1|1998770_1998905_-|delta-lysin-family-phenol-soluble-modulin
MSCLILRIFILIKEGVISMAQDIISTIGDLVKWIIDTVNKFTKK
>NZ_CP020354.1|WP_001105707.1|1999140_1999710_+|accessory-gene-regulator-AgrB
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQVLAKNIGKLIVMYTIAYILNIFLFTLITNLTFYLIRRHAHGAHAPSSFWCYVESIILFILLPLVIVNFHINFLIMIILTVISLGVISVYAPAATKKKPIPVRLIKRKKYYAIIVSLTLFIITLIIKEPFAQFIQLGIIIEAITLLPIFFIKEDLK

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Crispr_ID: NZ_CP020354_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020354_7

2117791-2117880

Orphan

Consensus_repeat	Method
CAACTTTAGTTGTTAGGGGCTCTT	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NZ_CP020354_7

>merge|NZ_CP020354|7|2117791-2117880|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTTATGCAGTTGATGCGTAGCATCCAACTGTGTTCCTCTATTTTTCAACTTTAGTTGTTAGGGGCTTCT

>NZ_CP020354|7|5|2117791-2117880|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTT	ATGCAGTTGATGCGTAGCATCCAACTGTGTTCCTCTATTTTT
CAACTTTAGTTGTTAGGGGCTTCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020354.1\|WP_000334465.1\|2121754_2123560_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP020354.1\|WP_000123393.1\|2110619_2111993_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
NZ_CP020354.1\|WP_001792784.1\|2118999_2119158_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_000160304.1\|2108274_2108985_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NZ_CP020354.1\|WP_000908189.1\|2120740_2121523_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_CP020354.1\|WP_001123303.1\|2109748_2110162_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NZ_CP020354.1\|WP_001802298.1\|2118215_2118320_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_001127960.1\|2112925_2113864_-\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
NZ_CP020354.1\|WP_001292149.1\|2127957_2128392_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_CP020354.1\|WP_000070866.1\|2109105_2109549_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
NZ_CP020354.1\|WP_000083807.1\|2124240_2125779_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP020354.1\|WP_049311693.1\|2125813_2127946_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP020354.1\|WP_000808817.1\|2112664_2112895_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_000003755.1\|2115114_2115435_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP020354.1\|WP_001048297.1\|2129816_2137271_-\|DUF1542-domain-containing-protein	unknown	unknown	gnl\|CDD\|275089
NZ_CP020354.1\|WP_001024095.1\|2114297_2114963_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
NZ_CP020354.1\|WP_000648743.1\|2128391_2129498_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_CP020354.1\|WP_000019743.1\|2115436_2116417_+\|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl\|CDD\|224151
NZ_CP020354.1\|WP_000495681.1\|2116682_2117774_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_000370928.1\|2119815_2120673_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635

Protein	Function_ID	Function_description	E-value
NZ_CP020354.1\|WP_000334465.1\|2121754_2123560_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP020354.1\|WP_000123393.1\|2110619_2111993_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
NZ_CP020354.1\|WP_000160304.1\|2108274_2108985_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
NZ_CP020354.1\|WP_000908189.1\|2120740_2121523_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	3.34326e-106
NZ_CP020354.1\|WP_001123303.1\|2109748_2110162_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.14887e-46
NZ_CP020354.1\|WP_001127960.1\|2112925_2113864_-\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
NZ_CP020354.1\|WP_001292149.1\|2127957_2128392_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_CP020354.1\|WP_000070866.1\|2109105_2109549_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
NZ_CP020354.1\|WP_000083807.1\|2124240_2125779_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_CP020354.1\|WP_049311693.1\|2125813_2127946_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.08382e-67
NZ_CP020354.1\|WP_000003755.1\|2115114_2115435_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	2.83702e-17
NZ_CP020354.1\|WP_001048297.1\|2129816_2137271_-\|DUF1542-domain-containing-protein	gnl\|CDD\|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	8.44946e-109
NZ_CP020354.1\|WP_001024095.1\|2114297_2114963_-\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.27122e-47
NZ_CP020354.1\|WP_000648743.1\|2128391_2129498_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_CP020354.1\|WP_000019743.1\|2115436_2116417_+\|CDF-family-zinc-efflux-transporter-CzrB	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.20197e-108
NZ_CP020354.1\|WP_000370928.1\|2119815_2120673_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	1.99434e-58

>NZ_CP020354.1|WP_000495681.1|2116682_2117774_+|hypothetical-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYVQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKETTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>NZ_CP020354.1|WP_000019743.1|2115436_2116417_+|CDF-family-zinc-efflux-transporter-CzrB
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHAH
>NZ_CP020354.1|WP_000003755.1|2115114_2115435_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEIHTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>NZ_CP020354.1|WP_001024095.1|2114297_2114963_-|SDR-family-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGEQDIKDALTQFEIEKD
>NZ_CP020354.1|WP_001127960.1|2112925_2113864_-|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>NZ_CP020354.1|WP_000808817.1|2112664_2112895_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>NZ_CP020354.1|WP_000123393.1|2110619_2111993_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRISNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>NZ_CP020354.1|WP_001123303.1|2109748_2110162_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>NZ_CP020354.1|WP_000070866.1|2109105_2109549_-|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>NZ_CP020354.1|WP_000160304.1|2108274_2108985_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>NZ_CP020354.1|WP_001802298.1|2118215_2118320_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NZ_CP020354.1|WP_001792784.1|2118999_2119158_+|hypothetical-protein
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>NZ_CP020354.1|WP_000370928.1|2119815_2120673_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITTFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQDETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>NZ_CP020354.1|WP_000908189.1|2120740_2121523_-|ABC-transporter-ATP-binding-protein
MLIQLDQVGRMKQGKTILKNISWQINGGDKWILYGLNGAGKTTLLNILNAYEPATTGDVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEIRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSESYPTLAMIYVTHFIEEITSNFTKILLLKDGKSVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_CP020354.1|WP_000334465.1|2121754_2123560_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_CP020354.1|WP_000083807.1|2124240_2125779_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_CP020354.1|WP_049311693.1|2125813_2127946_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISSMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDIDGNTSFENEQTSYLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDAINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMVLITVLEEPLILPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NZ_CP020354.1|WP_001292149.1|2127957_2128392_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_CP020354.1|WP_000648743.1|2128391_2129498_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGGGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITIEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NZ_CP020354.1|WP_001048297.1|2129816_2137271_-|DUF1542-domain-containing-protein
MNLFRQQKFSIRKFNVGIFSALIATVTFISTNPTTASAAEQNQPAQNQPAQPADANTQPNANAGAQANPTAQPAAPANQGQPAVQPANQGGQANPAGGAAQPNTQPAGQGNQADPNNAAQAQPGNQATPANQAGQGNNQATPNNNATPANQTQPANAPAAAQPAAQPAAPVAANAQTQDPNASNTGEGSINTTLTFDDPAISTDENRQDPTVTVTDKVNGYSLINNGKIGFVNSELRRSDMFDKNNPQNYQAKGNVAALGRVNANDSTDHGNFNGISKTVNVKPDSELIINFTTMQTNSKQGATNLVIKDAKKNTELATVNVAKTGTAHLFKVPTDADRLDLQFIPDNTAVADASRITTNKDGYKYYSFIDNVGLFSGSHLYVKNRDLAPKATNNKEYTINTEIGNNGNFGASLKADQFKYEVTLPQGVTYVNDSLTTTFPNGNEDSTVLKNMTVNYDQNANKVTFTSQGVTTARGTHTKEVLFPDKSLKLSYKVNVANIDTPKNIDFNEKLTYRTASDVVINNAQPEVTLTADPFSVAVEMNKDALQQQVNSQVDNSHYTTASIAEYNKLKQQADTILNEDANHVETANRASQADIDGLVTKLQAALIDNQAAIAELDAKAQEKVTAAQQSKKVTQDEVAALVTKINNDKNNAIAEINKQTTSQGVTTEKDNGIAVLEQDVITPTVKPQAKQDIIQAVTTRKQQIKKSNASLQDEKDVANDKIGKIETKAIKDIDAATTNAQVEAIKTKAINDINQTTPATTAKAAALEEFDEVVQAQIDQAPLNPDTTNEEVAEAIERINAAKVSGVKAIEATTTAQDLERVKNEEISKIENITDSTQTKMDAYNEVKQAATARKAQNATVSNATNEEVAEADAAVDAAQKQGLHDIQVVKSKQEVADTKSKVIDKINAIQTQAKVKPAADTEVENAYNTRKQEIQNSNASTTEEKQAAYTELDTKKQEARTNLDAANTNSDVTTAKDNGIAAINQVQAATTKKSDAKAEIAQKASERKTAIEAMNDSTTEEQQAAKDKVDQAVVTANADIDNATANTDVDNAKTTNEATIAAITPDANVKPQAKQAIADKVQAQETAIDANNGSTTEEKTAAKQQAQTEKTTADAAIDAAHTNAEVEAAKNAEIAKIEAIQPATTTKDNAKEAIATKANERKTAIAQTQDITAEEIAAANADVDNAVTQANSNIEAANSQNDVDQAKTTGETSIDQVTPTVNKKATARNEITTILNNKLQEIQATPDATDEEKQAADAEANTENGKANQAISAATTNAQVDEAKANAEAAINAVTPKVVKKQAAKDEIDQLQATQTNVINNDQNATTEEKEAAIQQLATAVTDAKNNITAATDDNGVDQAKDAGKNSIQSTQPATAVKSNAKNDVDQAVTTQNQAIDNTTGATTEEKNAAKDLVLKAKEKAYQDILNAQTTNDVTQIKDQAVADIQGITADTTIKDVAKDELATKANEQKALIAQTADATTEEKEQANQQVDAQLTQGNQNIENAQSIDDVNTAKENAIQAIDPIQASTDVKTNARAELLTEMQNKITEILSDNTTTNEEKGKDIEPVRATYEEGLNNINTANTTGDVTTAKDTAVQKVQQLHANPVKKPAGKTALDQAAADRKTQIEQTPNASQQEINDAKQEVDAALNQAKTNVDQSSTNEYVDNAVKEGKAKINAVKTFSEYKKDALAKIADAYNAKVNEADNSNASTSSEIAEAKQKLAELKQTADQNVNQATSKDDIEVQIHNDLDNINDYTIPTGKKETATTDLYAYADQKKNNISADTNATQDEKQQAIKQVDQNVQTALESINNGVDNGDVDDALTQGKAAIDAIQVDATVKPKANQAIEVKAEDTKESIDQSDQLTAEEKTEALAMIKQITDQAKQGITDATTTAEVEKAKAQGLEAFDNIQIDSTEKQKAIEELETALDQIEAGVNVDADATTEEKEAFTNALEDILSKATEDISDQTTNAEIATVKNSALEQLKAQRINPEVKKNALEAIREVVNKQIEIIKNADADASAKEIARTDLGRYFDRFADKLDKTQTNAEVAELQNVTIPAIEAIVPQNDPDANDTNNGIDNNDATANSNANATPENTGQPNVSETTDNGKADASPTTPNNSDAATGETTATSATDDANDKPQANNNSSVDASTNSPTMDNDVTSKPEVESTNNGTTDKPVTETDNATPAESTTNNNSTTTATNENAPTGSTATAPTTASTEAASSADSKDNASVNDSKQNAEVNNSAESQSTNGKVAQPKSENKAKAEKDGRDSTNQSMVESTTETLPSADITEPNVPSNTSKDKEESTTNQTDAGQLKSETNVASNEADKSPSKADTEVSNKPSTSASSEAKDKMTSTNVSQKDDTATADTNDTQTSVGPVANNKAKDMQTNDMKASLATVSNGSNSANQDMLNVTNTDDHQAKTKSAQQGKVNKPKQQAKTLPDTGMSHNDDLPYAELALGAGMAFLIRRSTKKDQQTEE

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Crispr_ID: NZ_CP020354_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020354_8

2231242-2231441

Orphan

Consensus_repeat	Method
CTTCTATGTTGGGGCCCCGCCAACTTGCA	CRT

3 spacers

The CRISPR arrays of NZ_CP020354_8

>merge|NZ_CP020354|8|2231242-2231441|CRT
CTTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTATGCTGACTTTTCGTCACCTTCTATGTTGGGGCCCCGTTCCCCAACTTGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTTCTGTCAGCTTCTGTGTTGGGGCCCCGCCAACTTGTA

>NZ_CP020354|8|3|2231242-2231441|CRT
CTTCTATGTTGGGGCCCCGCCAACTTGCA	CATTATTGTATGCTGACTTTTCGTCAC
CTTCTATGTTGGGGCCCCGTTCCCCAACT	TGCATTGTCTGTAGAATTTCTTTTTGAAAT
TCTCTATGTTGGGGCCCCGCCAACTTGCA	CATTATTGTAAGCTGACTTTCTGTCAG
CTTCTGTGTTGGGGCCCCGCCAACTTGTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020354.1\|WP_000643988.1\|2232624_2233224_-\|molybdenum-cofactor-guanylyltransferase-MobA	unknown	unknown	gnl\|CDD\|234725
NZ_CP020354.1\|WP_001566779.1\|2227624_2227876_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_001161085.1\|2220206_2220524_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_000076929.1\|2236766_2237771_-\|molybdopterin-biosynthesis-protein-MoeB	unknown	unknown	gnl\|CDD\|181084
NZ_CP020354.1\|WP_000866971.1\|2233230_2233464_-\|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl\|CDD\|340452
NZ_CP020354.1\|WP_000051210.1\|2219797_2219962_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_000184405.1\|2229226_2230438_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NZ_CP020354.1\|WP_031866192.1\|2231015_2231201_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP020354.1\|WP_000413865.1\|2225970_2227236_-\|lipid-II:glycine-glycyltransferase-FemX	unknown	unknown	gnl\|CDD\|225224
NZ_CP020354.1\|WP_000503820.1\|2236229_2236736_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	unknown	unknown	gnl\|CDD\|223595
NZ_CP020354.1\|WP_000808495.1\|2233469_2233916_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|223391
NZ_CP020354.1\|WP_000230173.1\|2231582_2232605_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NZ_CP020354.1\|WP_000951058.1\|2228793_2229234_+\|winged-helix-DNA-binding-protein	unknown	unknown	gnl\|CDD\|197670
NZ_CP020354.1\|WP_000913018.1\|2237940_2238546_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226628
NZ_CP020354.1\|WP_000600971.1\|2227867_2228632_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
NZ_CP020354.1\|WP_000134527.1\|2235733_2236228_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NZ_CP020354.1\|WP_000139181.1\|2218756_2219665_-\|AEC-family-transporter	unknown	unknown	gnl\|CDD\|223751
NZ_CP020354.1\|WP_000602932.1\|2233929_2234415_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
NZ_CP020354.1\|WP_000066900.1\|2230539_2230890_-\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
NZ_CP020354.1\|WP_000259731.1\|2234411_2235671_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452

Protein	Function_ID	Function_description	E-value
NZ_CP020354.1\|WP_000643988.1\|2232624_2233224_-\|molybdenum-cofactor-guanylyltransferase-MobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	5.68918e-67
NZ_CP020354.1\|WP_000808495.1\|2233469_2233916_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	6.99133e-58
NZ_CP020354.1\|WP_000076929.1\|2236766_2237771_-\|molybdopterin-biosynthesis-protein-MoeB	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	3.67241e-132
NZ_CP020354.1\|WP_000866971.1\|2233230_2233464_-\|molybdopterin-converting-factor-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	8.16473e-25
NZ_CP020354.1\|WP_000184405.1\|2229226_2230438_+\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.65046e-73
NZ_CP020354.1\|WP_000413865.1\|2225970_2227236_-\|lipid-II:glycine-glycyltransferase-FemX	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	4.8324e-143
NZ_CP020354.1\|WP_000503820.1\|2236229_2236736_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	9.7838e-65
NZ_CP020354.1\|WP_000230173.1\|2231582_2232605_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
NZ_CP020354.1\|WP_000951058.1\|2228793_2229234_+\|winged-helix-DNA-binding-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.35323e-15
NZ_CP020354.1\|WP_000913018.1\|2237940_2238546_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	2.82843e-115
NZ_CP020354.1\|WP_000600971.1\|2227867_2228632_-\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	9.47288e-38
NZ_CP020354.1\|WP_000134527.1\|2235733_2236228_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	1.34747e-97
NZ_CP020354.1\|WP_000139181.1\|2218756_2219665_-\|AEC-family-transporter	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	7.28102e-43
NZ_CP020354.1\|WP_000602932.1\|2233929_2234415_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	1.51621e-50
NZ_CP020354.1\|WP_000066900.1\|2230539_2230890_-\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
NZ_CP020354.1\|WP_000259731.1\|2234411_2235671_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	1.46788e-157

>NZ_CP020354.1|WP_031866192.1|2231015_2231201_+|hypothetical-protein
MFRFISFGQLVVYSTTFIPKKDILQLNDLECDINVKEPLKIYYVVIFGSGTEITFSQNLFR
>NZ_CP020354.1|WP_000066900.1|2230539_2230890_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>NZ_CP020354.1|WP_000184405.1|2229226_2230438_+|MFS-transporter
MTNQGSLNKSPIFTKSFTINFFVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETKVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>NZ_CP020354.1|WP_000951058.1|2228793_2229234_+|winged-helix-DNA-binding-protein
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>NZ_CP020354.1|WP_000600971.1|2227867_2228632_-|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKNKLQSERVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFAIETVIVKSKNQSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>NZ_CP020354.1|WP_001566779.1|2227624_2227876_+|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLAIIHMGILAHSTYVYLY
>NZ_CP020354.1|WP_000413865.1|2225970_2227236_-|lipid-II:glycine-glycyltransferase-FemX
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMKTSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>NZ_CP020354.1|WP_001161085.1|2220206_2220524_+|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>NZ_CP020354.1|WP_000051210.1|2219797_2219962_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDLEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>NZ_CP020354.1|WP_000139181.1|2218756_2219665_-|AEC-family-transporter
MTEQFTMIILLIALGYFLKRINFIKATDSQVIATLVLNVTLPSLVIVNLNSAELKLSFSILPILMIIYGIVAKMIAVWFFRKYDNHMRGSVGMMTGAMNIGLFAYPLIEVIWPKTGLIYFGMADIGGAFVMFGITYFVGSYFSEGSDQFDFKYLGKKLLQSVPLVTYIVMFILNINHIHLPHVAIDFFSILSHANMPLSMILLGVMLNFTLERKYIPATIKYLCLHYGLALVAGLLVHVLLPVSDDMIKTTLLVTWMFPVGVAIISYGIQFKYRTLPFIGMTTNLTIIISIIILYVYQAVFV
>NZ_CP020354.1|WP_000230173.1|2231582_2232605_-|GTP-3',8-cyclase-MoaA
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>NZ_CP020354.1|WP_000643988.1|2232624_2233224_-|molybdenum-cofactor-guanylyltransferase-MobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>NZ_CP020354.1|WP_000866971.1|2233230_2233464_-|molybdopterin-converting-factor-subunit-1
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>NZ_CP020354.1|WP_000808495.1|2233469_2233916_-|molybdenum-cofactor-biosynthesis-protein-MoaE
MKQFEIVIEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>NZ_CP020354.1|WP_000602932.1|2233929_2234415_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHAKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRDEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>NZ_CP020354.1|WP_000259731.1|2234411_2235671_-|molybdopterin-molybdotransferase-MoeA
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVRDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETTTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQQDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFADGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>NZ_CP020354.1|WP_000134527.1|2235733_2236228_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSNQ
>NZ_CP020354.1|WP_000503820.1|2236229_2236736_-|molybdenum-cofactor-biosynthesis-protein-MoaB
MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>NZ_CP020354.1|WP_000076929.1|2236766_2237771_-|molybdopterin-biosynthesis-protein-MoeB
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKYRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>NZ_CP020354.1|WP_000913018.1|2237940_2238546_-|ATP-binding-cassette-domain-containing-protein
MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWKIPIIFVTHSNYEAEQMAHEIITIG

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Crispr_ID: NZ_CP020354_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP020354_9

2660107-2660242

Orphan

Consensus_repeat	Method
TTTCGTCGTCCCACCCCAACTTGCA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP020354_9

>merge|NZ_CP020354|9|2660107-2660242|CRISPRCasFinder
TTTCGTCGTCCCACCCCAACTTGCATTGTCTGTAGAAACTGGGAATTCAATTTCTCTTTGTCGTCCCACCCCAACTTGCACATTATTGTAGGCTGACTTTCCGCCAGCTTCTTTGTTGGGGCCCCGCCAACTTGCA

>NZ_CP020354|9|6|2660107-2660242|CRISPRCasFinder
TTTCGTCGTCCCACCCCAACTTGCA	TTGTCTGTAGAAACTGGGAATTCAATTTCT
CTTTGTCGTCCCACCCCAACTTGCA	CATTATTGTAGGCTGACTTTCCGCCAGCTTC
TTTGTTGGGGCCCCGCCAACTTGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP020354.1\|WP_000653261.1\|2655803_2656364_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|376089
NZ_CP020354.1\|WP_000244280.1\|2652084_2652585_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379326
NZ_CP020354.1\|WP_001159430.1\|2656527_2657766_+\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	unknown	unknown	gnl\|CDD\|274866
NZ_CP020354.1\|WP_000565310.1\|2652819_2653587_-\|tyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|226870
NZ_CP020354.1\|WP_000635624.1\|2665595_2666174_-\|imidazole-glycerol-phosphate-synthase-subunit-HisH	unknown	unknown	gnl\|CDD\|171871
NZ_CP020354.1\|WP_106669562.1\|2664143_2664902_-\|imidazole-glycerol-phosphate-synthase-subunit-HisF	unknown	unknown	gnl\|CDD\|234996
NZ_CP020354.1\|WP_000301927.1\|2651605_2652082_-\|peptide-methionine-(S)-S-oxide-reductase	unknown	unknown	gnl\|CDD\|235497
NZ_CP020354.1\|WP_000659677.1\|2654292_2654955_-\|capsular-polysaccharide-biosynthesis-protein-CapA	unknown	unknown	gnl\|CDD\|226453
NZ_CP020354.1\|WP_000639186.1\|2666717_2667731_-\|histidinol-phosphate-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|223157
NZ_CP020354.1\|WP_000240580.1\|2657729_2658035_+\|intracellular-adhesion-protein-D	unknown	unknown	gnl\|CDD\|188447
NZ_CP020354.1\|WP_000640266.1\|2666170_2666749_-\|imidazoleglycerol-phosphate-dehydratase-HisB	unknown	unknown	gnl\|CDD\|153419
NZ_CP020354.1\|WP_000842036.1\|2660389_2662432_-\|YSIRK-domain-containing-triacylglycerol-lipase-Lip1	unknown	unknown	gnl\|CDD\|224001
NZ_CP020354.1\|WP_000944142.1\|2668989_2669604_-\|ATP-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|172153
NZ_CP020354.1\|WP_000170492.1\|2663514_2664147_-\|bifunctional-phosphoribosyl-AMP-cyclohydrolase/phosphoribosyl-ATP-diphosphatase-HisIE	unknown	unknown	gnl\|CDD\|235067
NZ_CP020354.1\|WP_000571737.1\|2664898_2665603_-\|1-(5-phosphoribosyl)-5-((5--phosphoribosylamino)methylideneamino)imidazole-4--carboxamide-isomerase	unknown	unknown	gnl\|CDD\|172156
NZ_CP020354.1\|WP_001065591.1\|2669621_2670440_-\|ATP-phosphoribosyltransferase-regulatory-subunit	unknown	unknown	gnl\|CDD\|237044
NZ_CP020354.1\|WP_000930650.1\|2667746_2668997_-\|histidinol-dehydrogenase	unknown	unknown	gnl\|CDD\|172308
NZ_CP020354.1\|WP_000185863.1\|2653583_2654276_-\|polysaccharide-biosynthesis-tyrosine-autokinase	unknown	unknown	gnl\|CDD\|349772
NZ_CP020354.1\|WP_000723835.1\|2658890_2659943_+\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|226446
NZ_CP020354.1\|WP_000877369.1\|2658031_2658904_+\|intercellular-adhesin-biosynthesis-polysaccharide-N-deacetylase	unknown	unknown	gnl\|CDD\|188448

Protein	Function_ID	Function_description	E-value
NZ_CP020354.1\|WP_000653261.1\|2655803_2656364_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|376089	pfam18665, TetR_C_37, Tetracyclin repressor-like, C-terminal domain. IcaR belongs to the tetracycline repressor (TetR) family of proteins, which are involved in a wide variety of gene regulations. It binds to a 42 bp region immediately upstream of the icaA gene. This entry represents the C-terminal domain which is involved in dimerization.	2.88245e-28
NZ_CP020354.1\|WP_000244280.1\|2652084_2652585_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	5.52546e-13
NZ_CP020354.1\|WP_001159430.1\|2656527_2657766_+\|poly-beta-1,6-N-acetyl-D-glucosamine-synthase	gnl\|CDD\|274866	TIGR03937, Poly-beta-16-N-acetyl-D-glucosamine_synthase, poly-beta-1,6 N-acetyl-D-glucosamine synthase. Members of this protein family are biofilm-forming enzymes that polymerize N-acetyl-D-glucosamine residues in beta(1,6) linkage. One named members is IcaA (intercellular adhesin protein A), an enzyme that acts (with aid of subunit IcaD) in Polysaccharide Intercellular Adhesin (PIA) biosynthesis in Staphylococcus epidermis). The homologous member in E. coli is designated PgaC. Members are often encoded next to a polysaccharide deacetylase and involved in biofilm formation. Note that chitin, although also made from N-acetylglucosamine, is formed with beta-1,4 linkages.	0
NZ_CP020354.1\|WP_000565310.1\|2652819_2653587_-\|tyrosine-protein-phosphatase	gnl\|CDD\|226870	COG4464, CapC, Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	2.38228e-144
NZ_CP020354.1\|WP_000635624.1\|2665595_2666174_-\|imidazole-glycerol-phosphate-synthase-subunit-HisH	gnl\|CDD\|171871	PRK13142, hisH, imidazole glycerol phosphate synthase subunit HisH; Provisional.	2.23848e-128
NZ_CP020354.1\|WP_106669562.1\|2664143_2664902_-\|imidazole-glycerol-phosphate-synthase-subunit-HisF	gnl\|CDD\|234996	PRK02083, PRK02083, imidazole glycerol phosphate synthase subunit HisF; Provisional.	3.75839e-154
NZ_CP020354.1\|WP_000301927.1\|2651605_2652082_-\|peptide-methionine-(S)-S-oxide-reductase	gnl\|CDD\|235497	PRK05528, PRK05528, peptide-methionine (S)-S-oxide reductase.	9.37152e-105
NZ_CP020354.1\|WP_000659677.1\|2654292_2654955_-\|capsular-polysaccharide-biosynthesis-protein-CapA	gnl\|CDD\|226453	COG3944, COG3944, Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane].	1.17617e-89
NZ_CP020354.1\|WP_000639186.1\|2666717_2667731_-\|histidinol-phosphate-aminotransferase-family-protein	gnl\|CDD\|223157	COG0079, HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism].	5.60546e-84
NZ_CP020354.1\|WP_000240580.1\|2657729_2658035_+\|intracellular-adhesion-protein-D	gnl\|CDD\|188447	TIGR03932, IcaD_partial, intracellular adhesion protein D. Members of this protein family are IcaD (intracellular adhesion protein D), which with catalytic subunit IcaA forms an N-acetylglucosaminyltransferase. In the absence of IcaC, this enzyme forms N-acetylglucosamine oligomers up to 20 in length. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	3.14464e-30
NZ_CP020354.1\|WP_000640266.1\|2666170_2666749_-\|imidazoleglycerol-phosphate-dehydratase-HisB	gnl\|CDD\|153419	cd07914, IGPD, Imidazoleglycerol-phosphate dehydratase. Imidazoleglycerol-phosphate dehydratase (IGPD; EC 4.2.1.19) catalyzes the dehydration of imidazole glycerol phosphate to imidazole acetol phosphate, the sixth step of histidine biosynthesis in plants and microorganisms where the histidine is synthesized de novo. There is an internal repeat in the protein domain that is related by pseudo-dyad symmetry, perhaps as a result of an ancient gene duplication. The apo-form of IGPD exists as a catalytically inactive trimer which, in the presence of specific divalent metal cations such as manganese (Mn2+), cobalt (Co2+), cadmium (Cd2+), nickel (Ni2+), iron (Fe2+) and zinc (Zn2+), assembles to form a biologically active high molecular weight metalloenzyme; a 24-mer with 4-3-2 symmetry. Each 24-mer has 24 active sites, and contains around 1.5 metal ions per monomer, each monomer contributing residues to three separate active sites. IGPD enzymes are monofunctional in fungi, plants, archaea and some eubacteria while they are encoded as bifunctional enzymes in other eubacteria, such that the enzyme is fused to histidinol-phosphate phosphatase, the penultimate enzyme of the histidine biosynthesis pathway. The histidine biosynthesis pathway is a potential target for development of herbicides, and IGPD is a target for the triazole phosphonate herbicides.	2.40504e-103
NZ_CP020354.1\|WP_000842036.1\|2660389_2662432_-\|YSIRK-domain-containing-triacylglycerol-lipase-Lip1	gnl\|CDD\|224001	COG1075, LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only].	1.58472e-82
NZ_CP020354.1\|WP_000944142.1\|2668989_2669604_-\|ATP-phosphoribosyltransferase	gnl\|CDD\|172153	PRK13584, hisG, ATP phosphoribosyltransferase.	8.56054e-134
NZ_CP020354.1\|WP_000170492.1\|2663514_2664147_-\|bifunctional-phosphoribosyl-AMP-cyclohydrolase/phosphoribosyl-ATP-diphosphatase-HisIE	gnl\|CDD\|235067	PRK02759, PRK02759, bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE.	1.98613e-110
NZ_CP020354.1\|WP_000571737.1\|2664898_2665603_-\|1-(5-phosphoribosyl)-5-((5--phosphoribosylamino)methylideneamino)imidazole-4--carboxamide-isomerase	gnl\|CDD\|172156	PRK13587, PRK13587, 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Provisional.	6.62111e-168
NZ_CP020354.1\|WP_001065591.1\|2669621_2670440_-\|ATP-phosphoribosyltransferase-regulatory-subunit	gnl\|CDD\|237044	PRK12294, hisZ, ATP phosphoribosyltransferase regulatory subunit; Provisional.	4.50318e-175
NZ_CP020354.1\|WP_000930650.1\|2667746_2668997_-\|histidinol-dehydrogenase	gnl\|CDD\|172308	PRK13770, PRK13770, histidinol dehydrogenase; Provisional.	0
NZ_CP020354.1\|WP_000185863.1\|2653583_2654276_-\|polysaccharide-biosynthesis-tyrosine-autokinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	2.83977e-84
NZ_CP020354.1\|WP_000723835.1\|2658890_2659943_+\|acyltransferase-family-protein	gnl\|CDD\|226446	COG3936, COG3936, Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation [Carbohydrate transport and metabolism].	1.1329e-114
NZ_CP020354.1\|WP_000877369.1\|2658031_2658904_+\|intercellular-adhesin-biosynthesis-polysaccharide-N-deacetylase	gnl\|CDD\|188448	TIGR03933, Poly-beta-16-N-acetyl-D-glucosamine_N-deacetylase, intercellular adhesin biosynthesis polysaccharide N-deacetylase. A common motif in bacterial biosynthesis of polysaccharide for export is modification that follows polymerization. This model describes a subfamily of polysaccharide N-deacetylases that acts on poly-beta-1,6-N-acetyl-D-glyscosamine as produced by Staphylococcus epidermidis and S. aureus. The end product in these species is designated polysaccharide intercellular adhesin (PIA), and this gene designated icaB (intercellular adhesion protein B). [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Cellular processes, Pathogenesis].	9.91129e-151

>NZ_CP020354.1|WP_000723835.1|2658890_2659943_+|acyltransferase-family-protein
MKKIRLELVYLRAIICAIIIITHLLTQITLKHENMEGGSLVLQFYIRNIVIFGTPCFIILSQLLTTLNYQKVTYRYLTTRVKYILIPYILMGLFYSYSESLLTDSSFNKQFIENVLLGQWYGYFIVVIMQFFILSYIIFKINYNLFNSKILLLLSFILQQSFLYYFTNNTAFHDTVLHYYPLSENTIIFGWIFYFFLGAYMGYNYERVLNFLERYLVIMIVLAVATYFVFIALANGDYWNVTSFSYSLTPYNSIMFIVILGICTHFKTMLFNTIQMISAFSFFIYLLHPIILDSLFAYTNIFEDNTIVFLAISLLFILGLCIGVGMILREFYIFRFIIGKQPYKLNINAY
>NZ_CP020354.1|WP_000877369.1|2658031_2658904_+|intercellular-adhesin-biosynthesis-polysaccharide-N-deacetylase
MKYRKLIILVLSILIILPVSTLDGHHIANADDDSPKKLKYKENSALALNYHRVRKANFLNNFIYFFSSSKEIKNYSVSQSQFESQIKWLKSHDAKFLTLKEFLYYKKKGKFPKRSVWINFDDMDETIYENAYPILKKYKIPATGFIITGHVGEENFHNLDMISKKELKEMYKTGLWEFETHTHDLHNLSKNNKSKLMKASEATIIKDLNKSEKYLTKNFKKSQKTIAYPYGLMNDDKLPVIKKAGLKYGFSLEEKAVTPNSNDYYIPRILISDDAFEHLIKRWDGFHEKD
>NZ_CP020354.1|WP_000240580.1|2657729_2658035_+|intracellular-adhesion-protein-D
MVKPRQREYPTLKSSLNIVRETALIAISCVFWIYCLVVLLVYIGTIFEIHDESINTIRVALNIENTEILDIFETMGIFAIIIFVFFTISILIQKWQRGRES
>NZ_CP020354.1|WP_001159430.1|2656527_2657766_+|poly-beta-1,6-N-acetyl-D-glucosamine-synthase
MQFFNFLLFYPVFMSIYWIVGSIYFYFTREIRYSLNKKPDINVDELEGITFLLACYNESETIEDTLSNVLALKYEKKEIIIINDGSSDNTAELIYKIKENNDFIFVDLQENRGKANALNQGIKQASYDYVMCLDADTIVDQDAPYYMIENFKHDPKLGAVTGNPRIRNKSSILGKIQTIEYASLIGCIKRSQTLAGAVNTISGVFTLFKKSAVVDVGYWDTDMITEDIAVSWKLHLRGYRIKYEPLAMCWMLVPETLGGLWKQRVRWAQGGHEVLLRDFFSTMKTKRFPLYILMFEQIISILWVYIVLLYLGYLFITANFLDYTFMTYSFSIFLLSSFTMTFINVIQFTVALFIDSRYEKKNMAGLIFVSWYPTVYWIINAAVVLVAFPKALKRKKGGYATWSSPDRGNTQR
>NZ_CP020354.1|WP_000653261.1|2655803_2656364_-|TetR/AcrR-family-transcriptional-regulator
MKDKIIDNAITLFSEKGYDGTTLDDIAKSVNIKKASLYYHFDSKKSIYEQSVKCCFDYLNNIIMMNQNKSNYSIDALYQFLFEFIFDIEERYIRMYVQLSNTPEEFSGNIYGQIQDLNQSLSKEIAKFYDESKIKMTKEDFQNLILLFLESWYLKASFSQKFGAVEESKSQFKDEVYSLLNIFLKK
>NZ_CP020354.1|WP_000659677.1|2654292_2654955_-|capsular-polysaccharide-biosynthesis-protein-CapA
MKEKFDLVKLLNILKKNIKLLLILPAICLVVSAALTFFVMPDKYTASTQILVNMKKSSSDLAFQNVQSSLQSVNTYTEIIKSPRILDKVSREFDGQYSTAELNSFLKVTNQTNSQIITVSVTTGNKSESDKIVNRISKVFAHDMPKIMSVDNVTILSSAHDNAVKVSPIVSVNLVISIIVGIVLAILIIFLKELLDKRIKTEEDVESQLGLPILGSIQKF
>NZ_CP020354.1|WP_000185863.1|2653583_2654276_-|polysaccharide-biosynthesis-tyrosine-autokinase
MTNTRRSTSSLIVHEQPKSPISEKFRGIRSNIMFANPDSAVQSIVITSEAPGAGKSTIAANLAVAYAQAGYKTLIVDGDMRKPTQHYIFNLPNNEGLSSLLLNWSTYQDSIISTEIQDLDVLTSGPIPPNPSELITSRAFANLYDTLLMNYNFVIIDTPPVNTVTDAQLFSKFTGNVVYVVNSENNNKDEVKKGKELIEATGAKLLGVVLNRMPKDKSASYYAYYGTDES
>NZ_CP020354.1|WP_000565310.1|2652819_2653587_-|tyrosine-protein-phosphatase
MIDIHNHILVDIDDGPKTIEKSIALLKQAKDEGVTSIVATPHHLHPRYDNTFQQVLVKLAELRTHPEVQALDIKLFPGQEIRITDSILKGLDNGSIQGINRSKYLLIEFPTGEVPHYTKQLFFEIQSRGYIPIIAHPERNRSIAKNPEILYELVANGALSQLTSSSLVGGFGKNIQKLSLQFIECNLAHFVASDAHSCDQRPFLMQELFHNHKLKKYSNDIEALLRNASSVINDNFVYLDRPTKPGKVKSFLKWF
>NZ_CP020354.1|WP_000244280.1|2652084_2652585_-|GNAT-family-N-acetyltransferase
MVLRKVIMQDLDQIIALENIVFSPEEAATREALKLRIEQIQETFIVAEKNDEVIGYINGPVIKERYISDDLFKNVSTNNSEGGYISVLGLVVAPNYQGQGIAGRLLNYFETLAKNHHRHGVTLTCRESLISFYEKYGYRNEGVSESCHGGIKWYNLVKNIKKDDEV
>NZ_CP020354.1|WP_000301927.1|2651605_2652082_-|peptide-methionine-(S)-S-oxide-reductase
MAVVYVAGGCLWGVEAFFATIPGIIHTEAGRANGRSSKLDGPYDGYAECVKLHIDDRMLTITDIMNYLFEIIDPYSVNRQGNDIGEKYRTGLYSCLDDHLIEARQFIERRKDRDQIAVEVLPLSNYIKSAEEHQQHLEKYPEDMHMCHISKDLLNKYK
>NZ_CP020354.1|WP_000842036.1|2660389_2662432_-|YSIRK-domain-containing-triacylglycerol-lipase-Lip1
MKSQNKYSIRKFSVGASSILIATLLFLSGGQAQAAEKQVNMGNSQEDTVTAQSIGDQQTRENANYQRENGVDEQQHTENLTKNLHNDKTISEENHRKTDDLNKDQLKDDKKSSLNNKNIQRDTTKNNNANPSDVNQGLEQAINDGKQSKVASQQQSKEADNSQDSNANNNLPSQSRIKEAPSLNKLDQTSQREIVNETEIEKVQPQQNNQANDKITNYNFNNEQEVKPQKDEKTLSVSDLKNNQKSPVEPTKDNDKKNGLNLLKSSAVATLPNKGTKELTAKAKDDQTNKVAKQGQYKNQDPIVLVHGFNGFTDDINPSVLAHYWGGNKMNIRQDLEENGYKAYEASISAFGSNYDRAVELYYYIKGGRVDYGAAHAAKYGHERYGKTYEGIYKDWKPGQKVHLVGHSMGGQTIRQLEELLRNGNREEIEYQKKHGGEISPLFKGNHDNMISSITTLGTPHNGTHASDLAGNEALVRQIVFDIGKMFGNKNSRVDFGLAQWGLKQKPNESYIDYVKRVKQSNLWKSKDNGFYDLTREGATDLNRKTSLNPNIVYKTYTGEATHKALNSDRQKADLNMFFPFVITGNLIGKATEKEWRENDGLVSVISSQHPFNQAYTKATDKIQKGIWQVTPTKHDWDHVDFVGQDSSDTVRTREELQDFWHHLADDLVKTEKLTDTKQA
>NZ_CP020354.1|WP_000170492.1|2663514_2664147_-|bifunctional-phosphoribosyl-AMP-cyclohydrolase/phosphoribosyl-ATP-diphosphatase-HisIE
MTKYKIDFSKGLVPAILQDNQTKQVLMLGYMNQEAFDKTIEDGVVCFYSRSKQRLWTKGETSGHTQRVKDIHVDCDNDTILIDVIPNGPTCHTGSQSCFNTEVPFSVQTLAQTVQDSAQSNNEKSYTKYLLTEGIEKITKKYGEEAFEVVIEAIKGDKKAFVSEVADELYHLFVLMHALGVDFSEIEAELARRHHKRNNFKGERQNIEQW
>NZ_CP020354.1|WP_106669562.1|2664143_2664902_-|imidazole-glycerol-phosphate-synthase-subunit-HisF
MIKKRIIPCLDVKDGRVVKGIQFKGLRDIGNPVDLAMYYNEAGADELVFLDISKTEEGHSLMLEVIEQTASRLFIPLTVGGGIQNLDDITQLLNHGADKVSLNSSALKNPQLIKQASDKFGRQCICIAIDSYYDPERKAHYCCTHGGKKMTNIKVYDWVQQVEQLGAGELLITSMGHDGMKQGFDIEHLANIKSLVNIPIIASGGGGNAQHFVELFDQTDVSAGLAASILHDRETTVQSIKEVIRQGGIAVR
>NZ_CP020354.1|WP_000571737.1|2664898_2665603_-|1-(5-phosphoribosyl)-5-((5--phosphoribosylamino)methylideneamino)imidazole-4--carboxamide-isomerase
MIELWPAIDLIGSTSVRLTEGKYDSEEKMSRSAEESIAYYSQFECVNRIHIVDLIGAKAQHAREFDYIKSLRRLTTKDIEVGGGIRTKSQIMDYFAAGINYCIVGTKGIQDTDWLKVMAHTFPGRIYLSVDAYGEDIKVNGWEEDTELNLFSFVRQLSDIPLGGIIYTDIAKDGKMSGPNFELTGQLVKATTIPVIASGGIRHQQDIQRLASLNVHAAIIGKAAHQASFWEGLK
>NZ_CP020354.1|WP_000635624.1|2665595_2666174_-|imidazole-glycerol-phosphate-synthase-subunit-HisH
MIVIVDYGLGNISNVKRAIEHLGYEVVVSNTSKIIDQAETIILPGVGHFKDAMSEIKRLNLNAILAKNTDKKMIGICLGMQLMYEHSDEGDASGLGFIPGNISRIQTEYPVPHLGWNNLVSKHPMLNQDVYFVHSYQAPMSENVIAYAQYGTDIPAIVQFNNYIGIQFHPEKSGTYGLQILRQAIQGGFIND
>NZ_CP020354.1|WP_000640266.1|2666170_2666749_-|imidazoleglycerol-phosphate-dehydratase-HisB
MIYQKQRNTAETQLNISISDDQSPSHINTGVGFLNHMLTLFTFHSGLSLNIEAQGDIDVDDHHVTEDIGIVIGQLLLEMIKDKKHFVRYGTMYIPMDETLARVVVDISGRPYLSFNASLSKEKVGTFDTELVEEFFRAVVINARLTTHIDLIRGGNTHHEIEAIFKAFSRALGIALTATDDQRVPSSKGVIE
>NZ_CP020354.1|WP_000639186.1|2666717_2667731_-|histidinol-phosphate-aminotransferase-family-protein
MIYIDKNESPVTPLDEKTMTSIISATPYNLYPDAAYEQFKEAYAKFYGLSPEQIIAGNGSDELIQKLMLIMPEGPALTLNPDFFMYQAYAAQVNREIAFVDAGSDLTFDLETILTKIDEVQPSFFIMSNPHNPSGKQFDTAFLTAIADKMKALNGYFVIDEAYLDYGTAYDVELAPHILRMRTLSKAFGIAGLRLGVLISTAGTIKHIQKIEHPYPLNVFTLNIATYIFRHREETRVFLTMQRQLAEQLKQIFDTHVADKMSVFPSNANFVLTKGSAAQQLGQYVYEQGFKPRFYGEPVMKGYVRYSIATASQLKQLEEIVKEWSAKYDLSKTTKHS
>NZ_CP020354.1|WP_000930650.1|2667746_2668997_-|histidinol-dehydrogenase
MLNAQQFLNQFSLEAPLDESLYPIIRDICQEVKVHGDKALKMYNLTFDHTKTDHLEISHEQIKAAFDTLDEKTKQALQQSYERIKAYQESIKQTNQQLEESVECYEIYHPLESVGIYVPGGKASYPSTVLMTATLAQVAGVENIVVVTPPQPNGVSQEVLAACYITQVNQVFQVGGAQSIAALTYGTETIPKVDKIVGPGNQFVAYAKKYLFGQVGIDQIAGPTEIALIIDDTADLDAIVYDVFAQAEHDELARTYVISEDAQVLKDLESRIAKALPNVDRYDIVSKSIANQHYLIHASNFDEACHVMNTIAPEHASIQTVNPQPYIEKVKYVGALFIGHYSPEVIGDYVAGPSHVLPTNRTARFTNGLSVNDFLTRNTVIHLSKDTFEQIADSAQHIAHVEALYNHQQSILIRQS
>NZ_CP020354.1|WP_000944142.1|2668989_2669604_-|ATP-phosphoribosyltransferase
MLRIAIAKGRLMDSLINYLDEIEYTKLSETLKNRERQLLLSVDNIECILVKGSDVPIYVEQGMADIGIVGSDILDERQYNVNNLLNMPFGACHFAVAAKPETTNYRKIATSYVHTAETYFKSKGIDVELIKLNGSVELACVVDMVDGIVDIVQTGTTLKANGLVEKQHISDINARLITNKAAYFKKSQLIEQFIRSLEVSIANA
>NZ_CP020354.1|WP_001065591.1|2669621_2670440_-|ATP-phosphoribosyltransferase-regulatory-subunit
MNNSEQLIALKESETAFLKYFNKADYELVDFSVVEKLDWKQLNHEDLQQMGERNFWQHEHQIYALRNDFTDQLLRYYSMYPTAATKVAYTGLIIRNNEAAVQVGLENYAPSLANVQQSLKLFIQFIQQQLRDNVHFVVLGHYQLLDALLDKSLQTPDILSMIEERNLSGLVTYLSTEHPIVQILKENTQQQLNVLEHYIPNDHPALVELKIWERWLHTQGYKDIHLDITAQPPRSYYTGLFIQCHFAENESRVLTGGYYKGSIEGFGLGLTL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP020354_1	1.2\|261601\|32\|NZ_CP020354\|CRT	261601-261632	32	NZ_CP020354.1	143123-143154	0	1.0
NZ_CP020354_1	1.2\|261601\|32\|NZ_CP020354\|CRT	261601-261632	32	NZ_CP020354.1	143181-143212	0	1.0
NZ_CP020354_1	1.2\|261601\|32\|NZ_CP020354\|CRT	261601-261632	32	NZ_CP020354.1	143239-143270	0	1.0
NZ_CP020354_1	1.2\|261601\|32\|NZ_CP020354\|CRT	261601-261632	32	NZ_CP020354.1	1325149-1325180	0	1.0
NZ_CP020354_1	1.2\|261601\|32\|NZ_CP020354\|CRT	261601-261632	32	NZ_CP020354.1	1413651-1413682	0	1.0
NZ_CP020354_1	1.2\|261601\|32\|NZ_CP020354\|CRT	261601-261632	32	NZ_CP020354.1	1413709-1413740	0	1.0
NZ_CP020354_1	1.2\|261601\|32\|NZ_CP020354\|CRT	261601-261632	32	NZ_CP020354.1	1914791-1914822	0	1.0
NZ_CP020354_1	1.2\|261601\|32\|NZ_CP020354\|CRT	261601-261632	32	NZ_CP020354.1	2265581-2265612	0	1.0
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	NZ_CP020354.1	1113851-1113880	0	1.0
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	NZ_CP020354.1	1113963-1113992	0	1.0
NZ_CP020354_1	1.1\|261546\|32\|NZ_CP020354\|CRT	261546-261577	32	NZ_CP020354.1	811665-811696	1	0.969
NZ_CP020354_1	1.2\|261601\|32\|NZ_CP020354\|CRT	261601-261632	32	NZ_CP020354.1	261712-261743	1	0.969
NZ_CP020354_1	1.2\|261601\|32\|NZ_CP020354\|CRT	261601-261632	32	NZ_CP020354.1	804519-804550	1	0.969
NZ_CP020354_1	1.2\|261601\|32\|NZ_CP020354\|CRT	261601-261632	32	NZ_CP020354.1	916869-916900	1	0.969
NZ_CP020354_1	1.2\|261601\|32\|NZ_CP020354\|CRT	261601-261632	32	NZ_CP020354.1	1626514-1626545	1	0.969
NZ_CP020354_3	3.4\|1109981\|37\|NZ_CP020354\|CRT	1109981-1110017	37	NZ_CP020354.1	1997221-1997257	1	0.973
NZ_CP020354_8	8.1\|2231271\|27\|NZ_CP020354\|CRT	2231271-2231297	27	NZ_CP020354.1	2231215-2231241	1	0.963
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	NZ_CP020354.1	1771626-1771655	1	0.967
NZ_CP020354_8	8.3\|2231386\|27\|NZ_CP020354\|CRT	2231386-2231412	27	NZ_CP020354.1	811609-811635	1	0.963
NZ_CP020354_9	9.2\|2660187\|31\|NZ_CP020354\|CRISPRCasFinder	2660187-2660217	31	NZ_CP020354.1	811665-811695	1	0.968
NZ_CP020354_1	1.1\|261546\|32\|NZ_CP020354\|CRT	261546-261577	32	NZ_CP020354.1	811609-811640	2	0.938
NZ_CP020354_1	1.1\|261546\|32\|NZ_CP020354\|CRT	261546-261577	32	NZ_CP020354.1	896154-896185	2	0.938
NZ_CP020354_1	1.1\|261546\|32\|NZ_CP020354\|CRT	261546-261577	32	NZ_CP020354.1	1606843-1606874	2	0.938
NZ_CP020354_1	1.3\|261656\|33\|NZ_CP020354\|CRT	261656-261688	33	NZ_CP020354.1	1606842-1606874	2	0.939
NZ_CP020354_3	3.1\|1109812\|37\|NZ_CP020354\|CRT	1109812-1109848	37	NZ_CP020354.1	1997221-1997257	2	0.946
NZ_CP020354_3	3.4\|1109981\|37\|NZ_CP020354\|CRT	1109981-1110017	37	NZ_CP020354.1	2265687-2265723	2	0.946
NZ_CP020354_4	4.1\|1199741\|26\|NZ_CP020354\|CRISPRCasFinder	1199741-1199766	26	NZ_CP020354.1	767333-767358	2	0.923
NZ_CP020354_4	4.1\|1199741\|26\|NZ_CP020354\|CRISPRCasFinder	1199741-1199766	26	NZ_CP020354.1	767389-767414	2	0.923
NZ_CP020354_4	4.1\|1199741\|26\|NZ_CP020354\|CRISPRCasFinder	1199741-1199766	26	NZ_CP020354.1	767445-767470	2	0.923
NZ_CP020354_4	4.1\|1199741\|26\|NZ_CP020354\|CRISPRCasFinder	1199741-1199766	26	NZ_CP020354.1	811629-811654	2	0.923
NZ_CP020354_4	4.1\|1199741\|26\|NZ_CP020354\|CRISPRCasFinder	1199741-1199766	26	NZ_CP020354.1	896140-896165	2	0.923
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	NZ_CP020354.1	143129-143158	2	0.933
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	NZ_CP020354.1	143187-143216	2	0.933
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	NZ_CP020354.1	143245-143274	2	0.933
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	NZ_CP020354.1	916865-916894	2	0.933
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	NZ_CP020354.1	1592310-1592339	2	0.933
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	NZ_CP020354.1	1924137-1924166	2	0.933
NZ_CP020354_8	8.3\|2231386\|27\|NZ_CP020354\|CRT	2231386-2231412	27	NZ_CP020354.1	811665-811691	2	0.926
NZ_CP020354_8	8.3\|2231386\|27\|NZ_CP020354\|CRT	2231386-2231412	27	NZ_CP020354.1	896159-896185	2	0.926
NZ_CP020354_8	8.3\|2231386\|27\|NZ_CP020354\|CRT	2231386-2231412	27	NZ_CP020354.1	1012851-1012877	2	0.926
NZ_CP020354_8	8.3\|2231386\|27\|NZ_CP020354\|CRT	2231386-2231412	27	NZ_CP020354.1	1113907-1113933	2	0.926
NZ_CP020354_8	8.3\|2231386\|27\|NZ_CP020354\|CRT	2231386-2231412	27	NZ_CP020354.1	1199704-1199730	2	0.926
NZ_CP020354_8	8.3\|2231386\|27\|NZ_CP020354\|CRT	2231386-2231412	27	NZ_CP020354.1	1325213-1325239	2	0.926
NZ_CP020354_8	8.3\|2231386\|27\|NZ_CP020354\|CRT	2231386-2231412	27	NZ_CP020354.1	2265645-2265671	2	0.926
NZ_CP020354_9	9.1\|2660132\|30\|NZ_CP020354\|CRISPRCasFinder	2660132-2660161	30	NZ_CP020354.1	757927-757956	2	0.933
NZ_CP020354_9	9.1\|2660132\|30\|NZ_CP020354\|CRISPRCasFinder	2660132-2660161	30	NZ_CP020354.1	804460-804489	2	0.933
NZ_CP020354_9	9.1\|2660132\|30\|NZ_CP020354\|CRISPRCasFinder	2660132-2660161	30	NZ_CP020354.1	847631-847660	2	0.933
NZ_CP020354_9	9.1\|2660132\|30\|NZ_CP020354\|CRISPRCasFinder	2660132-2660161	30	NZ_CP020354.1	1039240-1039269	2	0.933
NZ_CP020354_9	9.1\|2660132\|30\|NZ_CP020354\|CRISPRCasFinder	2660132-2660161	30	NZ_CP020354.1	1413534-1413563	2	0.933
NZ_CP020354_9	9.1\|2660132\|30\|NZ_CP020354\|CRISPRCasFinder	2660132-2660161	30	NZ_CP020354.1	1914849-1914878	2	0.933
NZ_CP020354_9	9.1\|2660132\|30\|NZ_CP020354\|CRISPRCasFinder	2660132-2660161	30	NZ_CP020354.1	2073263-2073292	2	0.933
NZ_CP020354_9	9.1\|2660132\|30\|NZ_CP020354\|CRISPRCasFinder	2660132-2660161	30	NZ_CP020354.1	2265698-2265727	2	0.933
NZ_CP020354_9	9.1\|2660132\|30\|NZ_CP020354\|CRISPRCasFinder	2660132-2660161	30	NZ_CP020354.1	2660243-2660272	2	0.933
NZ_CP020354_9	9.2\|2660187\|31\|NZ_CP020354\|CRISPRCasFinder	2660187-2660217	31	NZ_CP020354.1	811609-811639	2	0.935
NZ_CP020354_9	9.2\|2660187\|31\|NZ_CP020354\|CRISPRCasFinder	2660187-2660217	31	NZ_CP020354.1	896155-896185	2	0.935
NZ_CP020354_9	9.2\|2660187\|31\|NZ_CP020354\|CRISPRCasFinder	2660187-2660217	31	NZ_CP020354.1	1606844-1606874	2	0.935

1. spacer 1.2|261601|32|NZ_CP020354|CRT matches to position: 143123-143154, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggcaa	CRISPR spacer
cagagaatttcgaaaagaaattctacaggcaa	Protospacer
********************************

2. spacer 1.2|261601|32|NZ_CP020354|CRT matches to position: 143181-143212, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggcaa	CRISPR spacer
cagagaatttcgaaaagaaattctacaggcaa	Protospacer
********************************

3. spacer 1.2|261601|32|NZ_CP020354|CRT matches to position: 143239-143270, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggcaa	CRISPR spacer
cagagaatttcgaaaagaaattctacaggcaa	Protospacer
********************************

4. spacer 1.2|261601|32|NZ_CP020354|CRT matches to position: 1325149-1325180, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggcaa	CRISPR spacer
cagagaatttcgaaaagaaattctacaggcaa	Protospacer
********************************

5. spacer 1.2|261601|32|NZ_CP020354|CRT matches to position: 1413651-1413682, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggcaa	CRISPR spacer
cagagaatttcgaaaagaaattctacaggcaa	Protospacer
********************************

6. spacer 1.2|261601|32|NZ_CP020354|CRT matches to position: 1413709-1413740, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggcaa	CRISPR spacer
cagagaatttcgaaaagaaattctacaggcaa	Protospacer
********************************

7. spacer 1.2|261601|32|NZ_CP020354|CRT matches to position: 1914791-1914822, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggcaa	CRISPR spacer
cagagaatttcgaaaagaaattctacaggcaa	Protospacer
********************************

8. spacer 1.2|261601|32|NZ_CP020354|CRT matches to position: 2265581-2265612, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggcaa	CRISPR spacer
cagagaatttcgaaaagaaattctacaggcaa	Protospacer
********************************

9. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to position: 1113851-1113880, mismatch: 0, identity: 1.0

tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
tgcattgtctgtagaatttctttttgaaat	Protospacer
******************************

10. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to position: 1113963-1113992, mismatch: 0, identity: 1.0

tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
tgcattgtctgtagaatttctttttgaaat	Protospacer
******************************

11. spacer 1.1|261546|32|NZ_CP020354|CRT matches to position: 811665-811696, mismatch: 1, identity: 0.969

agaagctggcggaaagtcagcatacaataatg	CRISPR spacer
agaagctggcggaaagtcagcttacaataatg	Protospacer
********************* **********

12. spacer 1.2|261601|32|NZ_CP020354|CRT matches to position: 261712-261743, mismatch: 1, identity: 0.969

cagagaatttcgaaaagaaattctacaggcaa	CRISPR spacer
cagagaatttcgaaaagaaattctacaggtaa	Protospacer
*****************************.**

13. spacer 1.2|261601|32|NZ_CP020354|CRT matches to position: 804519-804550, mismatch: 1, identity: 0.969

cagagaatttcgaaaagaaattctacaggcaa	CRISPR spacer
cagagaatttcgaaaagaaattctacagacaa	Protospacer
****************************.***

14. spacer 1.2|261601|32|NZ_CP020354|CRT matches to position: 916869-916900, mismatch: 1, identity: 0.969

cagagaatttcgaaaagaaattctacaggcaa	CRISPR spacer
cagagaatttctaaaagaaattctacaggcaa	Protospacer
*********** ********************

15. spacer 1.2|261601|32|NZ_CP020354|CRT matches to position: 1626514-1626545, mismatch: 1, identity: 0.969

cagagaatttcgaaaagaaattctacaggcaa	CRISPR spacer
cagagaatttcgtaaagaaattctacaggcaa	Protospacer
************ *******************

16. spacer 3.4|1109981|37|NZ_CP020354|CRT matches to position: 1997221-1997257, mismatch: 1, identity: 0.973

ccccaacatagagaaattggaaccccaatttctacag	CRISPR spacer
ccccaacatagagaaattggaacaccaatttctacag	Protospacer
*********************** *************

17. spacer 8.1|2231271|27|NZ_CP020354|CRT matches to position: 2231215-2231241, mismatch: 1, identity: 0.963

cattattgtatgctgacttttcgtcac	CRISPR spacer
cattattgtaagctgacttttcgtcac	Protospacer
********** ****************

18. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to position: 1771626-1771655, mismatch: 1, identity: 0.967

tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaat	Protospacer
************************.*****

19. spacer 8.3|2231386|27|NZ_CP020354|CRT matches to position: 811609-811635, mismatch: 1, identity: 0.963

cattattgtaagctgactttctgtcag	CRISPR spacer
cattattgtaagctgactttccgtcag	Protospacer
*********************.*****

20. spacer 9.2|2660187|31|NZ_CP020354|CRISPRCasFinder matches to position: 811665-811695, mismatch: 1, identity: 0.968

cattattgtaggctgactttccgccagcttc	CRISPR spacer
cattattgtaagctgactttccgccagcttc	Protospacer
**********.********************

21. spacer 1.1|261546|32|NZ_CP020354|CRT matches to position: 811609-811640, mismatch: 2, identity: 0.938

agaagctggcggaaagtcagcatacaataatg	CRISPR spacer
agaagctgacggaaagtcagcttacaataatg	Protospacer
********.************ **********

22. spacer 1.1|261546|32|NZ_CP020354|CRT matches to position: 896154-896185, mismatch: 2, identity: 0.938

agaagctggcggaaagtcagcatacaataatg	CRISPR spacer
agaggctggcggaaagtcagcttacaataatg	Protospacer
***.***************** **********

23. spacer 1.1|261546|32|NZ_CP020354|CRT matches to position: 1606843-1606874, mismatch: 2, identity: 0.938

agaagctggcggaaagtcagcatacaataatg	CRISPR spacer
agaagctggcggaaagtcagcttacgataatg	Protospacer
********************* ***.******

24. spacer 1.3|261656|33|NZ_CP020354|CRT matches to position: 1606842-1606874, mismatch: 2, identity: 0.939

tagaagctggcggaaagtcagcatacaataatg	CRISPR spacer
tagaagctggcggaaagtcagcttacgataatg	Protospacer
********************** ***.******

25. spacer 3.1|1109812|37|NZ_CP020354|CRT matches to position: 1997221-1997257, mismatch: 2, identity: 0.946

ccccaacatagagaaattggatcaccaatttcaacag	CRISPR spacer
ccccaacatagagaaattggaacaccaatttctacag	Protospacer
********************* ********** ****

26. spacer 3.4|1109981|37|NZ_CP020354|CRT matches to position: 2265687-2265723, mismatch: 2, identity: 0.946

ccccaacatagagaaattggaaccccaatttctacag	CRISPR spacer
ccccaacatagagaaattggattcccaatttctacag	Protospacer
********************* .**************

27. spacer 4.1|1199741|26|NZ_CP020354|CRISPRCasFinder matches to position: 767333-767358, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacacagaagcaggcgg	Protospacer
*************.****** *****

28. spacer 4.1|1199741|26|NZ_CP020354|CRISPRCasFinder matches to position: 767389-767414, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacatagaagcagacgg	Protospacer
******************** *.***

29. spacer 4.1|1199741|26|NZ_CP020354|CRISPRCasFinder matches to position: 767445-767470, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacataaaagcaggcgg	Protospacer
***************.**** *****

30. spacer 4.1|1199741|26|NZ_CP020354|CRISPRCasFinder matches to position: 811629-811654, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacacagaagctgacgg	Protospacer
*************.********.***

31. spacer 4.1|1199741|26|NZ_CP020354|CRISPRCasFinder matches to position: 896140-896165, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacacagaggctggcgg	Protospacer
*************.***.********

32. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to position: 143129-143158, mismatch: 2, identity: 0.933

tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaat	Protospacer
*******.****************.*****

33. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to position: 143187-143216, mismatch: 2, identity: 0.933

tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaat	Protospacer
*******.****************.*****

34. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to position: 143245-143274, mismatch: 2, identity: 0.933

tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaat	Protospacer
*******.****************.*****

35. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to position: 916865-916894, mismatch: 2, identity: 0.933

tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
tgcattgcctgtagaatttcttttagaaat	Protospacer
*******.**************** *****

36. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to position: 1592310-1592339, mismatch: 2, identity: 0.933

tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaat	Protospacer
*******.****************.*****

37. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to position: 1924137-1924166, mismatch: 2, identity: 0.933

tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
tgcattgtctgtagaatttcctttcgaaat	Protospacer
********************.***.*****

38. spacer 8.3|2231386|27|NZ_CP020354|CRT matches to position: 811665-811691, mismatch: 2, identity: 0.926

cattattgtaagctgactttctgtcag	CRISPR spacer
cattattgtaagctgactttccgccag	Protospacer
*********************.*.***

39. spacer 8.3|2231386|27|NZ_CP020354|CRT matches to position: 896159-896185, mismatch: 2, identity: 0.926

cattattgtaagctgactttctgtcag	CRISPR spacer
cattattgtaagctgactttccgccag	Protospacer
*********************.*.***

40. spacer 8.3|2231386|27|NZ_CP020354|CRT matches to position: 1012851-1012877, mismatch: 2, identity: 0.926

cattattgtaagctgactttctgtcag	CRISPR spacer
cattattgtaagctgacttttcgtcag	Protospacer
********************..*****

41. spacer 8.3|2231386|27|NZ_CP020354|CRT matches to position: 1113907-1113933, mismatch: 2, identity: 0.926

cattattgtaagctgactttctgtcag	CRISPR spacer
cattattgtaagctgacttttcgtcag	Protospacer
********************..*****

42. spacer 8.3|2231386|27|NZ_CP020354|CRT matches to position: 1199704-1199730, mismatch: 2, identity: 0.926

cattattgtaagctgactttctgtcag	CRISPR spacer
cattattgtaagctgacttttcgtcag	Protospacer
********************..*****

43. spacer 8.3|2231386|27|NZ_CP020354|CRT matches to position: 1325213-1325239, mismatch: 2, identity: 0.926

cattattgtaagctgactttctgtcag	CRISPR spacer
cattattgtaagctgacttttcgtcag	Protospacer
********************..*****

44. spacer 8.3|2231386|27|NZ_CP020354|CRT matches to position: 2265645-2265671, mismatch: 2, identity: 0.926

cattattgtaagctgactttctgtcag	CRISPR spacer
cattattgtaagctgacttttcgtcag	Protospacer
********************..*****

45. spacer 9.1|2660132|30|NZ_CP020354|CRISPRCasFinder matches to position: 757927-757956, mismatch: 2, identity: 0.933

ttgtctgtagaaactgggaattcaatttct	CRISPR spacer
ttgtctgtagaaattgggaatccaatttct	Protospacer
*************.*******.********

46. spacer 9.1|2660132|30|NZ_CP020354|CRISPRCasFinder matches to position: 804460-804489, mismatch: 2, identity: 0.933

ttgtctgtagaaactgggaattcaatttct	CRISPR spacer
ttgtctgtagaaattgggaatccaatttct	Protospacer
*************.*******.********

47. spacer 9.1|2660132|30|NZ_CP020354|CRISPRCasFinder matches to position: 847631-847660, mismatch: 2, identity: 0.933

ttgtctgtagaaactgggaattcaatttct	CRISPR spacer
ttgtctgtagaaattgggaatccaatttct	Protospacer
*************.*******.********

48. spacer 9.1|2660132|30|NZ_CP020354|CRISPRCasFinder matches to position: 1039240-1039269, mismatch: 2, identity: 0.933

ttgtctgtagaaactgggaattcaatttct	CRISPR spacer
ttgtctgtagaaattgggaatccaatttct	Protospacer
*************.*******.********

49. spacer 9.1|2660132|30|NZ_CP020354|CRISPRCasFinder matches to position: 1413534-1413563, mismatch: 2, identity: 0.933

ttgtctgtagaaactgggaattcaatttct	CRISPR spacer
ttgtctgtagaaattgggaatccaatttct	Protospacer
*************.*******.********

50. spacer 9.1|2660132|30|NZ_CP020354|CRISPRCasFinder matches to position: 1914849-1914878, mismatch: 2, identity: 0.933

ttgtctgtagaaactgggaattcaatttct	CRISPR spacer
ttgtctgtagaaattgggaatccaatttct	Protospacer
*************.*******.********

51. spacer 9.1|2660132|30|NZ_CP020354|CRISPRCasFinder matches to position: 2073263-2073292, mismatch: 2, identity: 0.933

ttgtctgtagaaactgggaattcaatttct	CRISPR spacer
ttgtctgtagaaattgggaatccaatttct	Protospacer
*************.*******.********

52. spacer 9.1|2660132|30|NZ_CP020354|CRISPRCasFinder matches to position: 2265698-2265727, mismatch: 2, identity: 0.933

ttgtctgtagaaactgggaattcaatttct	CRISPR spacer
ttgtctgtagaaattgggaatccaatttct	Protospacer
*************.*******.********

53. spacer 9.1|2660132|30|NZ_CP020354|CRISPRCasFinder matches to position: 2660243-2660272, mismatch: 2, identity: 0.933

ttgtctgtagaaactgggaattcaatttct	CRISPR spacer
ttgtctgtagaaattgggaatccaatttct	Protospacer
*************.*******.********

54. spacer 9.2|2660187|31|NZ_CP020354|CRISPRCasFinder matches to position: 811609-811639, mismatch: 2, identity: 0.935

cattattgtaggctgactttccgccagcttc	CRISPR spacer
cattattgtaagctgactttccgtcagcttc	Protospacer
**********.************.*******

55. spacer 9.2|2660187|31|NZ_CP020354|CRISPRCasFinder matches to position: 896155-896185, mismatch: 2, identity: 0.935

cattattgtaggctgactttccgccagcttc	CRISPR spacer
cattattgtaagctgactttccgccagcctc	Protospacer
**********.*****************.**

56. spacer 9.2|2660187|31|NZ_CP020354|CRISPRCasFinder matches to position: 1606844-1606874, mismatch: 2, identity: 0.935

cattattgtaggctgactttccgccagcttc	CRISPR spacer
cattatcgtaagctgactttccgccagcttc	Protospacer
******.***.********************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	NZ_CP040462	Enterococcus sp. M190262 plasmid pM190262, complete sequence	41880-41909	6	0.8
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	NZ_CP034684	Bacillus sp. BD59S plasmid pBTBD59S1, complete sequence	33236-33265	6	0.8
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	KM359505	Prochlorococcus phage P-TIM68, complete genome	102712-102741	6	0.8
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	NZ_KY940428	UNVERIFIED: Bacillus sp. (in: Bacteria) strain PUMK-07 plasmid pMK-07, complete sequence	107756-107785	6	0.8
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	NZ_CP041978	Bacillus pacificus strain NCCP 15909 plasmid unnamed1, complete sequence	12746-12775	6	0.8
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	NC_011655	Bacillus cereus AH187 plasmid pAH187_270, complete sequence	83379-83408	6	0.8
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	NZ_CP029457	Bacillus cereus strain FORC087 plasmid pFORC087.3, complete sequence	55620-55649	6	0.8
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	NC_010924	Bacillus cereus strain AH187 plasmid pCER270, complete sequence	139788-139817	6	0.8
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	NC_011777	Bacillus cereus AH820 plasmid pAH820_272, complete sequence	97420-97449	6	0.8
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	CP045776	Bacillus paranthracis strain CFSAN068816 plasmid p1CFSAN068816, complete sequence	129103-129132	6	0.8
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	CP041980	Bacillus paranthracis strain NCCP 15910 plasmid unnamed, complete sequence	296472-296501	6	0.8
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	NC_016792	Bacillus cereus NC7401 plasmid pNCcld, complete sequence	138657-138686	6	0.8
NZ_CP020354_1	1.1\|261546\|32\|NZ_CP020354\|CRT	261546-261577	32	NZ_CP044300	Escherichia coli strain P59A plasmid pP59A-2, complete sequence	114276-114307	8	0.75
NZ_CP020354_5	5.1\|1913389\|33\|NZ_CP020354\|CRISPRCasFinder	1913389-1913421	33	MT150133	Enterobacteria phage vB_EcoM_IME540, complete genome	25909-25941	8	0.758
NZ_CP020354_5	5.1\|1913389\|33\|NZ_CP020354\|CRISPRCasFinder	1913389-1913421	33	MK234886	Escherichia phage AnYang, complete genome	114958-114990	8	0.758
NZ_CP020354_5	5.1\|1913389\|33\|NZ_CP020354\|CRISPRCasFinder	1913389-1913421	33	MF036691	Serratia phage CBH8, complete genome	7593-7625	8	0.758
NZ_CP020354_5	5.1\|1913389\|33\|NZ_CP020354\|CRISPRCasFinder	1913389-1913421	33	MF036690	Serratia phage CHI14, complete genome	7593-7625	8	0.758
NZ_CP020354_5	5.1\|1913389\|33\|NZ_CP020354\|CRISPRCasFinder	1913389-1913421	33	MF036692	Serratia phage X20, complete genome	7813-7845	8	0.758
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	NC_013085	Synechococcus phage S-RSM4, complete genome	71945-71974	8	0.733
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	FM207411	Synechococcus phage S-RSM4 complete genome	71945-71974	8	0.733
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	MW117966	Synechococcus phage S-H9-1, complete genome	132425-132454	9	0.7
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	HM452126	Aeromonas phage phiAS5, complete genome	16075-16104	9	0.7
NZ_CP020354_8	8.2\|2231327\|30\|NZ_CP020354\|CRT	2231327-2231356	30	JX238501	Bacillus phage phiAGATE, complete genome	76143-76172	10	0.667

1. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to NZ_CP040462 (Enterococcus sp. M190262 plasmid pM190262, complete sequence) position: , mismatch: 6, identity: 0.8

tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
tattttgtctgtaggatatctttttgaaaa	Protospacer
*.. **********.** ***********

2. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to NZ_CP034684 (Bacillus sp. BD59S plasmid pBTBD59S1, complete sequence) position: , mismatch: 6, identity: 0.8

-tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
atgaggt-tctgtagtttttctttttgaaat	Protospacer
 ** . * *******  **************

3. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to KM359505 (Prochlorococcus phage P-TIM68, complete genome) position: , mismatch: 6, identity: 0.8

tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
tcaatgatctgtataatttcttttggaaat	Protospacer
*  ** .****** ********** *****

4. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to NZ_KY940428 (UNVERIFIED: Bacillus sp. (in: Bacteria) strain PUMK-07 plasmid pMK-07, complete sequence) position: , mismatch: 6, identity: 0.8

-tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
atgaggt-tctgtagtttttctttttgaaat	Protospacer
 ** . * *******  **************

5. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to NZ_CP041978 (Bacillus pacificus strain NCCP 15909 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

-tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
atgaggt-tctgtagtttttctttttgaaat	Protospacer
 ** . * *******  **************

6. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to NC_011655 (Bacillus cereus AH187 plasmid pAH187_270, complete sequence) position: , mismatch: 6, identity: 0.8

-tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
atgaggt-tctgtagtttttctttttgaaat	Protospacer
 ** . * *******  **************

7. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to NZ_CP029457 (Bacillus cereus strain FORC087 plasmid pFORC087.3, complete sequence) position: , mismatch: 6, identity: 0.8

-tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
atgaggt-tctgtagtttttctttttgaaat	Protospacer
 ** . * *******  **************

8. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to NC_010924 (Bacillus cereus strain AH187 plasmid pCER270, complete sequence) position: , mismatch: 6, identity: 0.8

-tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
atgaggt-tctgtagtttttctttttgaaat	Protospacer
 ** . * *******  **************

9. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to NC_011777 (Bacillus cereus AH820 plasmid pAH820_272, complete sequence) position: , mismatch: 6, identity: 0.8

-tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
atgaggt-tctgtagtttttctttttgaaat	Protospacer
 ** . * *******  **************

10. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to CP045776 (Bacillus paranthracis strain CFSAN068816 plasmid p1CFSAN068816, complete sequence) position: , mismatch: 6, identity: 0.8

-tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
atgaggt-tctgtagtttttctttttgaaat	Protospacer
 ** . * *******  **************

11. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to CP041980 (Bacillus paranthracis strain NCCP 15910 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

-tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
atgaggt-tctgtagtttttctttttgaaat	Protospacer
 ** . * *******  **************

12. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to NC_016792 (Bacillus cereus NC7401 plasmid pNCcld, complete sequence) position: , mismatch: 6, identity: 0.8

-tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
atgaggt-tctgtagtttttctttttgaaat	Protospacer
 ** . * *******  **************

13. spacer 1.1|261546|32|NZ_CP020354|CRT matches to NZ_CP044300 (Escherichia coli strain P59A plasmid pP59A-2, complete sequence) position: , mismatch: 8, identity: 0.75

agaagctggcggaaagtcagcatacaataatg	CRISPR spacer
agaagctggcggaacttcagcattagttaaac	Protospacer
**************  *******  . ***

14. spacer 5.1|1913389|33|NZ_CP020354|CRISPRCasFinder matches to MT150133 (Enterobacteria phage vB_EcoM_IME540, complete genome) position: , mismatch: 8, identity: 0.758

ttgcctgtagaatttcttttttgaaattctcta	CRISPR spacer
taacaaagagaatttctttttcaaaattctcta	Protospacer
* .*  . *************..**********

15. spacer 5.1|1913389|33|NZ_CP020354|CRISPRCasFinder matches to MK234886 (Escherichia phage AnYang, complete genome) position: , mismatch: 8, identity: 0.758

ttgcctgtagaatttcttttttgaaattctcta	CRISPR spacer
taacaaagagaatttctttttcaaaattctcta	Protospacer
* .*  . *************..**********

16. spacer 5.1|1913389|33|NZ_CP020354|CRISPRCasFinder matches to MF036691 (Serratia phage CBH8, complete genome) position: , mismatch: 8, identity: 0.758

ttgcctgt---agaatttcttttttgaaattctcta	CRISPR spacer
---gatgtgaaaggatttcttttttgaaattatctt	Protospacer
     ***   **.***************** ***

17. spacer 5.1|1913389|33|NZ_CP020354|CRISPRCasFinder matches to MF036690 (Serratia phage CHI14, complete genome) position: , mismatch: 8, identity: 0.758

ttgcctgt---agaatttcttttttgaaattctcta	CRISPR spacer
---gatgtgaaaggatttcttttttgaaattatctt	Protospacer
     ***   **.***************** ***

18. spacer 5.1|1913389|33|NZ_CP020354|CRISPRCasFinder matches to MF036692 (Serratia phage X20, complete genome) position: , mismatch: 8, identity: 0.758

ttgcctgt---agaatttcttttttgaaattctcta	CRISPR spacer
---gatgtgaaaggatttcttttttgaaattatctt	Protospacer
     ***   **.***************** ***

19. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to NC_013085 (Synechococcus phage S-RSM4, complete genome) position: , mismatch: 8, identity: 0.733

tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
tgagagaattgtagagtttctttttgaaat	Protospacer
** .  . .******.**************

20. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to FM207411 (Synechococcus phage S-RSM4 complete genome) position: , mismatch: 8, identity: 0.733

tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
tgagagaattgtagagtttctttttgaaat	Protospacer
** .  . .******.**************

21. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to MW117966 (Synechococcus phage S-H9-1, complete genome) position: , mismatch: 9, identity: 0.7

tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
taagagaattgtagagtttctttttgaaat	Protospacer
*. .  . .******.**************

22. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to HM452126 (Aeromonas phage phiAS5, complete genome) position: , mismatch: 9, identity: 0.7

tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
aaatatgtctgtagaattgcttgttgaaga	Protospacer
 .   ************* *** *****.

23. spacer 8.2|2231327|30|NZ_CP020354|CRT matches to JX238501 (Bacillus phage phiAGATE, complete genome) position: , mismatch: 10, identity: 0.667

tgcattgtctgtagaatttctttttgaaat	CRISPR spacer
ccttttgtctgtataatttctttttcttca	Protospacer
. . ********* ***********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

736103 : 743924

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000244415.1\|736103_737159_-	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
WP_000149344.1\|737158_737845_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037807.1\|737819_738293_-	DoxX family protein	NA	NA	NA	NA
WP_001093562.1\|738635_739076_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_000604990.1\|739355_739940_-	hypothetical protein	NA	NA	NA	NA
WP_001062972.1\|740038_740752_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000941336.1\|740755_741175_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_000446724.1\|741176_741845_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000604515.1\|742195_742789_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.2e-38	43.5
WP_001217797.1\|742772_743924_+	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	2.1e-23	36.1

DBSCAN-SWA_2

755895 : 770547

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663024.1\|755895_756954_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	7.9e-22	26.7
WP_000197271.1\|757248_757791_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000429006.1\|758391_759309_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	2.1e-07	22.0
WP_031835073.1\|759399_759501_+	hypothetical protein	NA	NA	NA	NA
WP_000193751.1\|759578_761084_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_000930014.1\|761424_761925_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_001068497.1\|761944_762811_-	DMT family transporter	NA	NA	NA	NA
WP_000692521.1\|763611_764010_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_000855505.1\|763972_766078_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000562498.1\|766195_767167_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000499195.1\|767680_767836_+	hypothetical protein	NA	NA	NA	NA
WP_000876318.1\|767874_768846_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_001245573.1\|768832_769789_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_000616840.1\|769785_770547_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	6.5e-18	31.6

DBSCAN-SWA_3

1014359 : 1022832

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000861572.1\|1014359_1014842_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7
WP_001010406.1\|1014828_1015953_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000174053.1\|1015956_1016661_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
WP_000848350.1\|1016660_1016924_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666799.1\|1016925_1017597_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_000032727.1\|1017589_1019779_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.0e-140	39.7
WP_000483712.1\|1019757_1021242_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	7.2e-45	31.5
WP_000030811.1\|1021234_1022263_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.4e-62	41.7
WP_000238670.1\|1022265_1022832_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.6e-29	40.1

DBSCAN-SWA_4

1563873 : 1572185

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001213908.1\|1563873_1564659_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
WP_000924214.1\|1564784_1565675_-	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
WP_001062177.1\|1565684_1567031_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
WP_000683933.1\|1567144_1568245_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
WP_000624580.1\|1568247_1568925_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_001283055.1\|1569055_1570162_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_001217247.1\|1570385_1572185_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	3.5e-54	36.0

DBSCAN-SWA_5

1641616 : 1650659

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364542.1\|1641616_1642135_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
WP_000594995.1\|1642156_1644430_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.2e-62	28.8
WP_000749795.1\|1644632_1646912_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_001160682.1\|1647186_1647447_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_001112045.1\|1647465_1648605_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001019167.1\|1648627_1649653_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005768.1\|1649654_1650659_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_6

1776680 : 1842757

Staphylococcus_phage(95.83%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049311740.1\|1776680_1783241_-	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	4.2e-307	96.7
WP_000836463.1\|1783566_1783878_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	6.3e-52	99.0
WP_001108727.1\|1783899_1786314_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.3
WP_001025061.1\|1786604_1787786_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	5.6e-218	100.0
WP_000526540.1\|1787895_1788849_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	1.4e-78	99.3
WP_000764419.1\|1788845_1789409_+	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
WP_000757543.1\|1789528_1789930_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000266096.1\|1790501_1791329_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001790712.1\|1791331_1791451_-	hypothetical protein	NA	NA	NA	NA
WP_001196354.1\|1791562_1792564_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
WP_001008551.1\|1792685_1793150_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
WP_001159022.1\|1793162_1794344_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	6.6e-227	99.7
WP_000493878.1\|1794354_1794987_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	2.2e-112	99.0
WP_000384185.1\|1794993_1796025_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	4.0e-196	98.8
WP_001261668.1\|1796517_1798020_-	FAD-dependent oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	1.9e-29	98.6
WP_000221177.1\|1798542_1798857_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	9.8e-53	98.1
WP_000989121.1\|1798856_1800149_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	5.0e-228	99.5
WP_001032833.1\|1800235_1801090_-	autolysin	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000384171.1\|1801365_1801590_-	hypothetical protein	NA	NA	NA	NA
WP_000671324.1\|1801788_1802259_+	RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	6.7e-82	98.7
WP_001153742.1\|1802371_1802815_+	competence protein ComK	NA	NA	NA	NA
WP_001030469.1\|1802801_1803245_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
WP_106669544.1\|1803540_1804176_+\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001096494.1\|1804615_1805329_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_000091441.1\|1805588_1805891_+	hypothetical protein	NA	NA	NA	NA
WP_001200542.1\|1806146_1806512_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
WP_000623470.1\|1806508_1806862_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	3.8e-21	94.0
WP_000453301.1\|1808858_1809692_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	3.0e-157	99.3
WP_000366170.1\|1809903_1810812_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	3.7e-137	99.3
WP_000933822.1\|1810936_1812130_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_000109917.1\|1812501_1814094_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.8
WP_072361841.1\|1814346_1815093_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	2.9e-143	99.6
WP_000672015.1\|1815097_1815571_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	5.5e-84	99.4
WP_000718107.1\|1815636_1815894_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000778537.1\|1815890_1816892_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	5.1e-188	98.8
WP_000348369.1\|1816896_1818375_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.6e-283	98.0
WP_072361838.1\|1818533_1818989_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	6.7e-79	98.6
WP_001789021.1\|1819291_1819942_+	calcium-binding protein	A0A2H4PQM8	Staphylococcus_phage	5.2e-56	98.6
WP_000070647.1\|1820022_1821018_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	2.1e-69	94.0
WP_000669019.1\|1821093_1821720_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	2.9e-96	96.6
WP_049311638.1\|1821760_1822102_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	3.0e-55	95.6
WP_000595156.1\|1822598_1822775_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	1.3e-25	94.8
WP_000864138.1\|1822972_1823530_-	ImmA/IrrE family metallo-endopeptidase	A0A2H4PQN8	Staphylococcus_phage	3.5e-77	96.2
WP_000375476.1\|1823900_1824077_-	hypothetical protein	NA	NA	NA	NA
WP_000070811.1\|1824087_1824471_-	hypothetical protein	NA	NA	NA	NA
WP_000747802.1\|1825155_1825602_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_001801861.1\|1826052_1826148_+	type I toxin-antitoxin system Fst family toxin PepA1	NA	NA	NA	NA
WP_001791232.1\|1826270_1826372_+	hypothetical protein	NA	NA	NA	NA
WP_000695818.1\|1826719_1827094_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_001792823.1\|1827115_1827520_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_000742594.1\|1827672_1828116_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_000072558.1\|1828763_1829882_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	7.6e-39	35.1
WP_106669545.1\|1829874_1831431_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	5.2e-288	99.4
WP_031865257.1\|1831595_1831730_-	hypothetical protein	NA	NA	NA	NA
WP_001038715.1\|1831794_1832514_-\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	5.4e-131	99.6
WP_001038757.1\|1832664_1833381_-\|protease	serine protease SplE	A0A2H4PQN5	Staphylococcus_phage	2.4e-131	99.2
WP_011447030.1\|1833482_1833590_+	hypothetical protein	NA	NA	NA	NA
WP_001038706.1\|1833538_1834258_-\|protease	serine protease SplD	A0A2H4PQP9	Staphylococcus_phage	5.1e-129	99.2
WP_001038867.1\|1834378_1835098_-\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	1.2e-130	99.2
WP_001039447.1\|1835155_1835878_-\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	2.4e-131	99.6
WP_001039430.1\|1836002_1836710_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	3.6e-127	97.4
WP_001092769.1\|1837673_1838252_+	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	5.8e-67	74.0
WP_025174387.1\|1838723_1838942_-	hypothetical protein	A0A2H4PQH0	Staphylococcus_phage	9.2e-26	80.6
WP_000550252.1\|1839197_1839671_+	hypothetical protein	NA	NA	NA	NA
WP_000543844.1\|1839675_1840467_+	DUF1828 domain-containing protein	NA	NA	NA	NA
WP_000782446.1\|1840836_1841820_-	bi-component leukocidin LukED subunit D	A0A2H4PQH7	Staphylococcus_phage	2.3e-185	99.1
WP_106669546.1\|1841821_1842757_-	beta-channel forming cytolysin	A0A2H4PQI5	Staphylococcus_phage	5.7e-173	99.3

DBSCAN-SWA_7

1977901 : 1994038

Staphylococcus_phage(77.78%)

integrase,terminase,coat

attL 1977039:1977058|attR 1992060:1992079

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1977039:1977058	attL	NA	NA	NA	NA
WP_001035612.1\|1977901_1978456_+	DUF4888 domain-containing protein	A0A1W6JQE5	Staphylococcus_phage	4.2e-59	67.2
WP_000022955.1\|1978675_1978846_-	hypothetical protein	NA	NA	NA	NA
WP_033842523.1\|1979073_1979997_-	hypothetical protein	NA	NA	NA	NA
WP_033842524.1\|1980010_1980604_-	hypothetical protein	NA	NA	NA	NA
WP_033842525.1\|1980596_1981088_-	hypothetical protein	NA	NA	NA	NA
WP_072466814.1\|1981426_1981996_-\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	1.3e-100	97.9
WP_000358778.1\|1981992_1982334_-	hypothetical protein	A0A1W6JQM3	Staphylococcus_phage	1.7e-58	100.0
WP_072466815.1\|1982336_1982864_-\|coat	spore coat protein	A0A1W6JQH7	Staphylococcus_phage	4.1e-88	98.3
WP_054192753.1\|1983092_1983671_-	hypothetical protein	A0A1W6JQG0	Staphylococcus_phage	1.2e-80	96.4
WP_001288441.1\|1983705_1984050_-	hypothetical protein	A0A1W6JQF3	Staphylococcus_phage	1.4e-57	100.0
WP_072466816.1\|1984759_1985401_-	pathogenicity island protein	Q4ZE67	Staphylococcus_phage	6.5e-112	93.9
WP_000356927.1\|1985397_1985778_-	hypothetical protein	Q4ZE71	Staphylococcus_phage	3.8e-67	96.8
WP_033842989.1\|1986107_1987808_-	DUF927 domain-containing protein	Q4ZE73	Staphylococcus_phage	4.5e-309	95.4
WP_033842991.1\|1987821_1988691_-	mobile element-associated protein	Q4ZE74	Staphylococcus_phage	3.2e-162	95.5
WP_001103939.1\|1988754_1989072_-	DUF1474 family protein	A0A1W6JQH0	Staphylococcus_phage	3.2e-19	57.0
WP_001058492.1\|1989074_1989284_-	hypothetical protein	Q4ZE76	Staphylococcus_phage	7.7e-30	95.7
WP_000708434.1\|1989276_1989423_-	hypothetical protein	NA	NA	NA	NA
WP_000481967.1\|1989419_1989737_-	helix-turn-helix domain-containing protein	A0A1W6JQE0	Staphylococcus_phage	9.2e-51	98.1
WP_000153640.1\|1989741_1989960_-	helix-turn-helix transcriptional regulator	A0A2H4JB11	uncultured_Caudovirales_phage	1.3e-19	66.7
WP_000620857.1\|1990132_1990807_+	helix-turn-helix transcriptional regulator	A0A2H4JGT9	uncultured_Caudovirales_phage	1.6e-39	45.8
WP_000179346.1\|1990820_1991993_+\|integrase	site-specific integrase	A0A1W6JQD3	Staphylococcus_phage	1.3e-219	97.9
WP_000240642.1\|1992061_1993678_-	chaperonin GroEL	A0A240F779	uncultured_virus	3.4e-157	54.7
1992060:1992079	attR	NA	NA	NA	NA
WP_000917289.1\|1993753_1994038_-	co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP020355

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP020354

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection