CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP013850	Clostridium botulinum strain B305 chromosome, complete genome	7 crisprs	DEDDh,csa3,DinG,WYL,casR,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,csx1,cas3	17	11
NZ_CP013852	Clostridium botulinum strain B305 plasmid pRSJ6_2, complete sequence	0 crisprs	NA	0	3
NZ_CP013851	Clostridium botulinum strain B305 plasmid pRSJ6_1, complete sequence	0 crisprs	NA	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP013850_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP013850_1

1037292-1037384

Orphan

III-B

Consensus_repeat	Method
TTGAACAATAACATGAGATGTATTTAAAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP013850_1

>merge|NZ_CP013850|1|1037292-1037384|CRISPRCasFinder
TTGAACAATAACATGAGATGTATTTAAATAAAACAATTCCTCTTGAAGGTTGTTTGTTTTTCTATTGAACATTAACATGAGATGTATTTAAAT

>NZ_CP013850|1|1|1037292-1037384|CRISPRCasFinder
TTGAACAATAACATGAGATGTATTTAAAT	AAAACAATTCCTCTTGAAGGTTGTTTGTTTTTCTA
TTGAACATTAACATGAGATGTATTTAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP013850.1\|WP_085320503.1\|1034627_1036235_+\|LexA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|234688
NZ_CP013850.1\|WP_075143065.1\|1031955_1033662_+\|SEL1-like-repeat-protein	unknown	unknown	gnl\|CDD\|276807
NZ_CP013850.1\|WP_011948605.1\|1043991_1044675_+\|cobalt-ECF-transporter-T-component-CbiQ	unknown	unknown	gnl\|CDD\|274139
NZ_CP013850.1\|WP_085320504.1\|1046722_1048183_+\|uroporphyrinogen-III-C-methyltransferase	unknown	unknown	gnl\|CDD\|273643
NZ_CP013850.1\|WP_021134442.1\|1034003_1034549_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP013850.1\|WP_024933688.1\|1036512_1037070_+\|bifunctional-adenosylcobinamide-kinase/adenosylcobinamide-phosphate-guanylyltransferase	unknown	unknown	gnl\|CDD\|235612
NZ_CP013850.1\|WP_045539189.1\|1040448_1041411_+\|cobalamin-biosynthesis-protein	unknown	unknown	gnl\|CDD\|234919
NZ_CP013850.1\|WP_003356702.1\|1028951_1029623_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP013850.1\|WP_011948604.1\|1042991_1043711_+\|energy-coupling-factor-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|181384
NZ_CP013850.1\|WP_011986186.1\|1029622_1030651_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP013850.1\|WP_024933301.1\|1024460_1026068_+\|cell-shape-determining-protein	unknown	unknown	gnl\|CDD\|379716
NZ_CP013850.1\|WP_024933687.1\|1037495_1038260_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133381
NZ_CP013850.1\|WP_003492574.1\|1043714_1044014_+\|energy-coupling-factor-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|179494
NZ_CP013850.1\|WP_024932745.1\|1045714_1046587_+\|hydroxymethylbilane-synthase	unknown	unknown	gnl\|CDD\|234612
NZ_CP013850.1\|WP_024933686.1\|1038965_1040447_+\|cobyric-acid-synthase	unknown	unknown	gnl\|CDD\|234838
NZ_CP013850.1\|WP_024933685.1\|1041629_1042718_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|180542
NZ_CP013850.1\|WP_024933004.1\|1031002_1031551_+\|biotin-transporter-BioY	unknown	unknown	gnl\|CDD\|224187
NZ_CP013850.1\|WP_011986189.1\|1045098_1045746_+\|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|235504
NZ_CP013850.1\|WP_024933003.1\|1026431_1028792_-\|ABC-transporter-ATP-binding-protein/permease	unknown	unknown	gnl\|CDD\|213222
NZ_CP013850.1\|WP_024933300.1\|1022603_1022813_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|226489

Protein	Function_ID	Function_description	E-value
NZ_CP013850.1\|WP_085320503.1\|1034627_1036235_+\|LexA-family-transcriptional-regulator	gnl\|CDD\|234688	PRK00215, PRK00215, transcriptional repressor LexA.	2.20997e-32
NZ_CP013850.1\|WP_075143065.1\|1031955_1033662_+\|SEL1-like-repeat-protein	gnl\|CDD\|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	1.82323e-41
NZ_CP013850.1\|WP_011948605.1\|1043991_1044675_+\|cobalt-ECF-transporter-T-component-CbiQ	gnl\|CDD\|274139	TIGR02454, Uncharacterized_protein_MJ1089, cobalt ECF transporter T component CbiQ. This model represents the CbiQ component of the cobalt-specific ECF-type. CbiQ is now recognized as the T component of energy-coupling factor (ECF)-type transporters. The S component confers specificity (CbiM-N for cobalt systems), which CbiO is the ABC-family ATPase. In general, proteins found by this model reside next to the other putative subunits of the complex, identified as CbiN, CbiO, or CbiM. Note that the designation of cobalt transporter has been spread excessively among ECF system transporters with many other specificities. [Transport and binding proteins, Cations and iron carrying compounds].	7.56423e-29
NZ_CP013850.1\|WP_085320504.1\|1046722_1048183_+\|uroporphyrinogen-III-C-methyltransferase	gnl\|CDD\|273643	TIGR01469, Uroporphyrinogen-III_C-methyltransferase, uroporphyrin-III C-methyltransferase. This model represents enzymes, or enzyme domains, with uroporphyrin-III C-methyltransferase activity. This enzyme catalyzes the first step committed to the biosynthesis of either siroheme or cobalamin (vitamin B12) rather than protoheme (heme). Cobalamin contains cobalt while siroheme contains iron. Siroheme is a cofactor for nitrite and sulfite reductases and therefore plays a role in cysteine biosynthesis; many members of this family are CysG, siroheme synthase, with an additional N-terminal domain and with additional oxidation and iron insertion activities. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin].	5.21983e-120
NZ_CP013850.1\|WP_021134442.1\|1034003_1034549_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13156e-17
NZ_CP013850.1\|WP_024933688.1\|1036512_1037070_+\|bifunctional-adenosylcobinamide-kinase/adenosylcobinamide-phosphate-guanylyltransferase	gnl\|CDD\|235612	PRK05800, cobU, adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Validated.	1.31839e-84
NZ_CP013850.1\|WP_045539189.1\|1040448_1041411_+\|cobalamin-biosynthesis-protein	gnl\|CDD\|234919	PRK01209, cobD, cobalamin biosynthesis protein.	5.61387e-153
NZ_CP013850.1\|WP_003356702.1\|1028951_1029623_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.06578e-65
NZ_CP013850.1\|WP_011948604.1\|1042991_1043711_+\|energy-coupling-factor-ABC-transporter-permease	gnl\|CDD\|181384	PRK08319, PRK08319, energy-coupling factor ABC transporter permease.	2.23594e-119
NZ_CP013850.1\|WP_011986186.1\|1029622_1030651_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	7.55275e-59
NZ_CP013850.1\|WP_024933301.1\|1024460_1026068_+\|cell-shape-determining-protein	gnl\|CDD\|379716	pfam14897, EpsG, EpsG family. This family of proteins are related to the EpsG protein from B. subtilis. These proteins are likely glycosyl transferases belonging to the membrane protein GT-C clan.	0.00131254
NZ_CP013850.1\|WP_024933687.1\|1037495_1038260_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133381	cd01106, HTH_TipAL-Mta, Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA. Helix-turn-helix (HTH) TipAL, Mta, and SkgA transcription regulators, and related proteins, N-terminal domain. TipAL regulates resistance to and activation by numerous cyclic thiopeptide antibiotics, such as thiostrepton. Mta is a global transcriptional regulator; the N-terminal DNA-binding domain of Mta interacts directly with the promoters of mta, bmr, blt, and ydfK, and induces transcription of these multidrug-efflux transport genes. SkgA has been shown to control stationary-phase expression of catalase-peroxidase in Caulobacter crescentus. These proteins are comprised of distinct domains that harbor an N-terminal active (DNA-binding) site and a regulatory (effector-binding) site. The conserved N-terminal domain of these transcription regulators contains winged HTH motifs that mediate DNA binding. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Unique to this family, is a TipAL-like, lineage specific Bacilli subgroup, which has five conserved cysteines in the C-terminus of the protein.	1.17034e-48
NZ_CP013850.1\|WP_003492574.1\|1043714_1044014_+\|energy-coupling-factor-ABC-transporter-substrate-binding-protein	gnl\|CDD\|179494	PRK02898, PRK02898, energy-coupling factor ABC transporter substrate-binding protein.	1.72614e-41
NZ_CP013850.1\|WP_024932745.1\|1045714_1046587_+\|hydroxymethylbilane-synthase	gnl\|CDD\|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	3.23303e-147
NZ_CP013850.1\|WP_024933686.1\|1038965_1040447_+\|cobyric-acid-synthase	gnl\|CDD\|234838	PRK00784, PRK00784, cobyric acid synthase.	0
NZ_CP013850.1\|WP_024933685.1\|1041629_1042718_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|180542	PRK06358, PRK06358, threonine-phosphate decarboxylase; Provisional.	2.59591e-90
NZ_CP013850.1\|WP_024933004.1\|1031002_1031551_+\|biotin-transporter-BioY	gnl\|CDD\|224187	COG1268, BioY, Uncharacterized conserved protein [General function prediction only].	9.57293e-40
NZ_CP013850.1\|WP_011986189.1\|1045098_1045746_+\|NAD(P)-dependent-oxidoreductase	gnl\|CDD\|235504	PRK05562, PRK05562, NAD(P)-dependent oxidoreductase.	1.11865e-104
NZ_CP013850.1\|WP_024933003.1\|1026431_1028792_-\|ABC-transporter-ATP-binding-protein/permease	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	2.19141e-111
NZ_CP013850.1\|WP_024933300.1\|1022603_1022813_-\|acetyltransferase	gnl\|CDD\|226489	COG3981, COG3981, Predicted acetyltransferase [General function prediction only].	1.35488e-06

>NZ_CP013850.1|WP_024933688.1|1036512_1037070_+|bifunctional-adenosylcobinamide-kinase/adenosylcobinamide-phosphate-guanylyltransferase
MSNKNKVVLITGGVRSGKSEFAESLLQKEKSVLYIATAKITDKEMEHRVEKHKERRNSTWKTYEGYKGLGKIIKYYDEKNILLDCVTVMTTNLMFHKEIDYENIKEEELDEILEGIKKEFHDLIISVKEENKNIILVTNEVGYSIVPAYKLGRIFRDFQGIINKFIASLSDEVYLVTCGIPLKIK
>NZ_CP013850.1|WP_085320503.1|1034627_1036235_+|LexA-family-transcriptional-regulator
MKLESGQNRIAKSKHLGYGLLRGSKGTGKTTAAIYRGIYLKNQYCMYDKDKVLILSKNEENLNYIKNIYNDAEKTGVQYITLFSYNEDKLHFSSIYKIINKYFWEYIENNNLQYELASEKEKLAIIEECINDIKNEYKNLKYIDIKYSKFFLEEIQWMKDCMYYDLEEYKKADRIGRKTKKGEGPQRIIKNSKIREAVFKIMLLYNEKLKYKNLVDYSDVVSMSLKEASKNKENKFNHIIVDEAQNFTKLELKFIEALGRKNIYSSILFIADKEKNLNPKGWITKGRKLNNLQLGFEFKRFNLNKKIGINVKEEVETYIDDCNLKRKASNINTKNEDVSNVDNSNSEDKGLDKNIKNEWHKDKVNYDMDKFEYVDMKHRRSYEFSRGLGSNEEIIVEDQGSKEEYKEDELTKLPVFNDIAAGEPILMNPCVEGEFNIPKYWVRGMKNCFILKVKGDSMIGANIEDGNHVVIKRQQMAENKDIVAVNLEGSATLKRLLIKKSGAVLMPENKKYKPIEILEEGASIIGIAVGIIKGK
>NZ_CP013850.1|WP_021134442.1|1034003_1034549_+|GNAT-family-N-acetyltransferase
MGKIKQAKYNINGKTIIIRHAEVQDAEQLINVTKKVNQETDFLLKDPGEVCLTIKEEKEFIQSQIDSQVDLLIVPEVDGRIVGVCSLNGNTNKRIRHSAQFGLAVEKEYCGMGIGKNLMKSGIQWAKENGIFRITLEVDINNYRAISLYLKLGFEIEGTLRNDKMLSDGSYTSGYAMALLL
>NZ_CP013850.1|WP_075143065.1|1031955_1033662_+|SEL1-like-repeat-protein
MDRFSFLKIEWPEIYQIICNVEEKSKEDSNITLIELAQIAELITKYILKENHIEKNTELLDEINLLKDCHNLNADIVDFFYKIIIVSNKAIYEDYSDSIIAKSFLDKMFEILVWFAIEYGKTDYRKVDLSNMIPEDKDIFNKYIKSKSYNYTEKNIENETMIQPFTIENEEFFKEENNDDINRYEQDVFETNEEFHKRIRNHEIFTLGRIFIEKSNINETDEIVAFPFSVYKSIQIKIPIIDMLYIERAEFENLSIEEEEYILFSKLDIINDKICIDINNIYIEVSNNKCKVHAVVLDISYYESYEKYRNIIYSKKPIPIGMIKFNKNKYDINKNEMPVTINYYDWIQKYILNTKAYIEIHRYEAKTLCKENLYYILNGKLDIFDKKLLIREYYIQSKSLNKNFRINLHSSDPMNKLRCLVDKEEILAMNIIGEMYCKEQNYKEAMYWYKKAAEKGNSTSMNKIGVMYYEGKGVEQDYQKAMYWYKKSSQEGNFTAMSNIGSMYYNGQGVTEDYKKAMYWYKKSYKEGNFGVMRDIGSMYYEGKGVIKDYKKAMQCYKKASQIDNFIK
>NZ_CP013850.1|WP_024933004.1|1031002_1031551_+|biotin-transporter-BioY
MDKKLKVRDMIYSALFATIIGVSSYIIIPLPISPVPITAQSLAIMLAGCVLTPIQVVLSMVTFLLMGIIGIPVFSGGTAGFGIIVGKTGGYLIGFLVGAIIISLLVHKNKSLVNMLIACFIGGIIVVHILGSAWLGQVTSIGIKKAFLLGSAPFIPGDLIKAVVAVLIGRKLSKEMKRIGTQ
>NZ_CP013850.1|WP_011986186.1|1029622_1030651_+|HAMP-domain-containing-histidine-kinase
MNNKISVKMVVAFSLIVFFIVTSAVVISGLVVVFLSRFNVFTQPNPLILLGWLGIISIMVSTAIAQIIGKKVLSPISDLNKATKEVAKGNFNTRLSENSWTDEIREMAHSFNIMTHELGNIETLRDDFISNVSHEFKTPISAIEGYATLLQDDELSDEERREYIHKILISTKRLSSLSGNILQITELENQKILPLEQKYYLDEQIRQTILLFEYEWTKKNIILDINLDNITYIGSKELLAQVWQNILGNAIKFSHQNGTIQVTLTQTNEEVLITIKDNGIGMSEEVKNRVFEKFYQGDSSHYSDGNGLGLALVKRIIDICEGTIEISSHEAVGTEFTVKLPK
>NZ_CP013850.1|WP_003356702.1|1028951_1029623_+|response-regulator-transcription-factor
MFKVLVVEDDPALRKLFCTVLNKNGYKSIEAKDGDSALDILYREYIDLIISDIMMPNMDGYTLTKLIRESNNNVPILMITAKETFSDKQEGFRVGTDDYMVKPIDVNEMILRVGALLRRSQIINERRIVIGETTFLYDFLSVKYNNKELVLPQKEFYLIYKLVSTPNKIFTRQQLMDEIWGIESETDPRTVDVHINRLRDRFKDNKDFNIITIRGLGYKVVKQ
>NZ_CP013850.1|WP_024933003.1|1026431_1028792_-|ABC-transporter-ATP-binding-protein/permease
MLQIKDLKKVYTTGEFKQTALDGVSIDFRQSEFVAILGPSGSGKTTLLNMLGGLDQYDSGNMIINGLSTKKFGESDWDTYRNNSVGFIFQSYNLIPHLSIVDNVEMGMTLSGVPKSEKRQKATYVLEKVGLGNHIHKKPNQLSGGQMQRVAIARALANDPEIILADEPTGALDTQTSEQIMDLIKEIAKDKLVIMVTHNPELAEEYADRIVSFSDGKIVSDTNPFVSENNSNDYKPKKTSMNFLTALKLSGNNIVTKKWRTALTAFASSIGIIGVALVLSLSNGFNKQINEFEKDSLSNYPISIEQNSMSLGMSPSSKSKDKEKTEFPNKSMIYPYDSSENAAVHANAISTEYVDYIKKIDSSLINGISYTRNVNMNILKKQDGKVVSMNTSAAAFSTYPSKGDSFETDYLKSYYDVLAGSYPKNEKELVLVVDKYNQVDTNILEALGFSANSKNINFDSMIGTEYKLIYNDDYYTQSGKYFTVNGDTTNLENLYNNKNAVTLKISGIIRIKEDANVSNLSTGIVYSDQLAQDFIENAKNSQIVLAQKEAKYNVMNGNLLTEKTSTTTAAVHPTPSMATNTTSNVETKDDVLASLGATSSPTSISIYPVNFEAKDNITNYLDDWNKKLKEEDHIVYTDMASMITSLTGNIMDGITIVLVAFAGISLVVSMIMIGIIIYISVLERTKEIGVLRALGARKKDITRVFNAETFIIGFCSGGLGIAITYLLTIPVNSILYKFTDLNNVAQLNPLHAIALVITSIVLTMIGGAIPSKMAAKKDPVIALRSE
>NZ_CP013850.1|WP_024933301.1|1024460_1026068_+|cell-shape-determining-protein
MKKKIYSSFIVLSLIISMALIYFLMPVFSVKFYSFYIVFIIIALLLSINVSLNKGKESSKIYGIPVILIGLFIVMFIISLPIFRASSYKSLLPTPKYEEFSKNITPIDIKEIPTVNQKYAELLADKKLGEETSLGSKVELGTLTLQNVNGKLYYVAPLVHSGFMKWLLNDSTPGYITVSATDDKDVKLVTKLNGKDIKIRYQPKGFLNDDLKRHIYLKGTMNRGITDLTFELDDKGNPYYTATIYENKVGMSGQKAVGTAIVNPETGEVKKYTVENTPKWVDRIQPQSFVENNLKKWGKYIKGFFNFSGQDKLKTTEGTGVIYNNGKCYYYTGLTSVGKDESSIGFALVDTRTQQTRIFKIAGATETASMKSAEGKVQNLGYTSTFPILINVDNVPTYFTTLNDKNDLTKMFAMISVTDYNIIGTGESITECKSNYIKNLASKGNLINVGSTGKEENITDTIERINSYVVGNSTIYTFILKDHKDKIFNAGISISNELPITKEGDKVNIRYVDTKQDTINITSFDNIEFKQQSIK
>NZ_CP013850.1|WP_024933300.1|1022603_1022813_-|acetyltransferase
MDSTAELEKSKNFDERLSIVIDSSREEIVMDGIVPSSTYLAIRLVYNKLIGMIDIRHKLNDYLFQNDIL
>NZ_CP013850.1|WP_024933687.1|1037495_1038260_-|MerR-family-transcriptional-regulator
MHYKIKEVADMAGISVRMLHHYDKIGLLDPESVSDAGYRLYSDENLDRLQQILFFKELNFPLQEIKIILDSPNFNKKEALETHKQLLLEKKIRLEKIIQSVDKTISSIEGGIKMNKKEVLGAFDMTEIEEHQKKYSEEVKNKYGNTSAYKESNEKTSKYTKEDWNNIMKDWDIIYKKLANLMDKNPDDKEVQEYIHQFREHISKNFYDCTPEIFRGLGELYVNDERFTANIDKYKTGLSKFLREAINVYCDNIK
>NZ_CP013850.1|WP_024933686.1|1038965_1040447_+|cobyric-acid-synthase
MAKIMIQGTASSVGKSLIVAALCRIFKQDGYSVCPFKSQNMSLNSYITLDGKEMGRAQVLQAYAAGLEPEAYMNPILLKPTSDKKSQIIVNGKVYGNSTAMEYHNLKIKFKDMLKEQFEKLEEDFDIVVMEGAGSPAEINLRDRDIVNMGMAELVDAPVLLVGDIDKGGVFASLAGTMLLLNEGEKERVKGTIINKFRGDVEILKPGLDMLEDIIHIPCLGVVPYTRLQLEDEDGAVEFNKKAYAPIDIAVIKMPHISNFTDLDALKSEEDVSIRFVTSKEEFKEPDLLIIPGSKNTIEDLLYLRQCGLEERIKEYSREGKIIGICGGYQVLGSKIKDPYKVETDLGEIDGLNLLDMETIFEKEKVTTRVSAKLINEETENIVYGYEIHMGISKYSENIKPLFKIYDKNGEKVDYFDGAINEKGNVMGTYIHGVFDGVVFREKIINELRVKKGLKKKKSQMYEHMREKELDKLADIVRQSLDMEKIYSIIGMK
>NZ_CP013850.1|WP_045539189.1|1040448_1041411_+|cobalamin-biosynthesis-protein
MYLNITTNFIDIIIAVFIDWIVGDPYWFPHPVIYIGKLISFLEKKFRARVKNEENLKIYGEVIVMIVCFASFLIPFMILQAFKFNFYIYHGLNILIIWTTLAAKCLHEEAIKIYYALYKENIEEARLKLSYIVGRETKDLIGNEIMRADIETVAENASDGVIAPLFYAIIGGAPLAMMYKGINTMDSMLGYLNDKYRYIGFFPAKVDDIFNFIPARLTGILMCISAPIVGGNPFKSFKIMIRDRKNHKSPNCAYPEGATAAALKIQLGGTNVYFGQVVEKPTIGDKIKELAPIHIKESIKLMYASEALMIVMCTIIFKLF
>NZ_CP013850.1|WP_024933685.1|1041629_1042718_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MHGGDIYTEGILKEKELIDFSSNINPLGLPDSFKDNLQEALNWVQVYPDIQYRNLKRNLIDYLSFSLGYFYKEKVEKPNIKEENLVLGNGAVEIIDLAISNLKSISILVPSFVEYELCAKKWNVQIDYCNLNEDMTYNYENIKKSLEKTEGIILGNPNNPNGSVIDKEKFIYILDYCEKNNKIIILDEAFIEFTGKNSFSFLNLCERYKCIFIIRALTKFFSMPGIRFGYGISFNNEFLNKIREKQNPWNINCFAEIAVKYVLKDEDFIEKSINYIEKEKIFMHENLKKCDLFHSVYSTYSNFVLCKLKDITGDELKNRLLEKGFVLRVCKDFKNLNNNYVRFAIKTRELNQALVNILKEIK
>NZ_CP013850.1|WP_011948604.1|1042991_1043711_+|energy-coupling-factor-ABC-transporter-permease
MKKKYLFLLTTALVLALSQSAYAMHIAEGFLPPKWAALYFVLSAPFIVIGVKHIRQKTKKNKDLKMLLAVVAAYAFILSAMKIPSVTGSCSHPTGTGLAAIIFGPFVASVVGVIVLLFQAILLAHGGITTLGANTFSMGIVGPIVSYLIYKGLKNKNQKLAVFLAASLGDLATYTVTSLQLALSFPAKTGGVMAAFAKFATIFSLTQIPLAIIEGLITIMIFEFMMKYSKEELKTLSEV
>NZ_CP013850.1|WP_003492574.1|1043714_1044014_+|energy-coupling-factor-ABC-transporter-substrate-binding-protein
MKKQNIIITIVSVVVILASLFIGGARGGEFAGADDQAEGIIEEMNKDYEPWFESIWEPPSGEIESLLFASQAALGAGVIGYYIGKKKNAKNNNASIKNQ
>NZ_CP013850.1|WP_011948605.1|1043991_1044675_+|cobalt-ECF-transporter-T-component-CbiQ
MLLSKTSKLSNIHPLEKVILSIIPIVILGFTQNYIIVFCNILFFLFMNLISKNNKKIFAKITLEVTAFAAISSITFAFDYGIVYTLTLIFKSVSAGLCLSFFSLTTPIDDMLYCLGKKEYLKDICDIAKGMERFLVVINDEYNILYSSIKSRGGFDTFKLTIRNTGKMAALLFINTLSRWKIIKEGLDSRGYVGYMPYLDRNFDFSYIRFLSILSYIILILLLVIFF
>NZ_CP013850.1|WP_011986189.1|1045098_1045746_+|NAD(P)-dependent-oxidoreductase
MQEKYNFIALKSKRIRILIIGGGRAAFIKGKAFLDRGCSLYILAPKFSKDVLDLKTYDNVEFIKNNYDEKYILDKHLVVIATEDEEVNNEIRNNCDALSKLYIDCSDKDKSLCFNSFQRESKTMVLALNNKIGCPKATYFIGEKIKKDLERYDNYIEYVTYIRSITKNNPMKDEIIDFICSNDFHFFFEKGYGNLILSMFYGGMDFEFCNSHTKK
>NZ_CP013850.1|WP_024932745.1|1045714_1046587_+|hydroxymethylbilane-synthase
MNFVIATRRSKLAQVQTEIIIDLLNKKHDIECEKLLIETVGDKILEVSLDKIGGKGLFVKDIEVAMLEQRADAAVHSMKDVPYEMPKGFEIIAIPEREDVRDAFISLDNIKFKDLRKGAKIGTSSRRRAAQLKLLRPDLDIVPIRGNVQTRIEKIKKENLDGIILAVAGLKRVNLDHLITDYFDTKEMVPAIGQGALGIEVMEEHPKKDLFKDLDHYNSKICVLAERAFMRELDGDCHSTIGAYASIKDNIMHIIGIFERKNKIIKKEITGTKDQYEKLGISLAEHILKD
>NZ_CP013850.1|WP_085320504.1|1046722_1048183_+|uroporphyrinogen-III-C-methyltransferase
MSKVYLIGAGPGDEELITLKAIRALKKCTAVMYDRLANGELLKYLAPNCEIYYCGKEPGCHYKSQDEINKMLVKLAKEGHIVGRIKGGDPYVFGRGGEEALDILEENIEFEVIPGVTSPVSVLNYAGIPITHRGISRGFHIFTAMTKDKLDIDWKSVVNIGGTLVFLMGLGRLELITKGLIENGMDKEGKVAVVMKGTTSKQKKVIGNLENIVEKVKEAKLESPVIIVVGEVVSFSDKLNWYEKKPLFGRNICITRTKEQAKELKVQLLDLGAEVTEINSIEIKNTEDNLKSYLSKLKEYDYIALTSVNAVKIFFDYLIKENIDIRNINAKFAAIGPATSEAIRIRGIMPSIKSKHFVAESLFEEMRKHIQKGDKILVPRSKDARPFLVDALRKEGCTVDEVHIYGTLCGQCTYTERFENADTVLFTSPSTVRNMISMVGIDSIKEKSIIAIGPITARELDKNNIECSICDEYSINGIIDKLLDLN

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Crispr_ID: NZ_CP013850_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP013850_2

2010118-2010212

TypeIII

III-B

Consensus_repeat	Method
GGTTGAACATTAACATGAGATGTATTTAA	CRISPRCasFinder

1 spacers

cas10,csm2gr11,csm3gr7

The CRISPR arrays of NZ_CP013850_2

>merge|NZ_CP013850|2|2010118-2010212|CRISPRCasFinder
GGTTGAACATTAACATGAGATGTATTTAAATAATACAGTCCAAAGTATAAGTTCACCTTAAAATTGGGTTGAACATTAACATAAGATGTATTTAA

>NZ_CP013850|2|2|2010118-2010212|CRISPRCasFinder
GGTTGAACATTAACATGAGATGTATTTAA	ATAATACAGTCCAAAGTATAAGTTCACCTTAAAATTG
GGTTGAACATTAACATAAGATGTATTTAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP013850.1\|WP_024933470.1\|2011229_2012120_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_CP013850.1\|WP_024933468.1\|2012969_2014376_-\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|340904
NZ_CP013850.1\|WP_024933386.1\|2001051_2001507_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378897
NZ_CP013850.1\|WP_024933462.1\|2019448_2020198_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NZ_CP013850.1\|WP_024933310.1\|2006593_2006887_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013850.1\|WP_024933464.1\|2016868_2019019_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
NZ_CP013850.1\|WP_024933385.1\|2004182_2005103_+\|PhzF-family-phenazine-biosynthesis-protein	unknown	unknown	gnl\|CDD\|223461
NZ_CP013850.1\|WP_024933384.1\|2005414_2005831_-\|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl\|CDD\|225039
NZ_CP013850.1\|WP_011986682.1\|2002365_2003859_-\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NZ_CP013850.1\|WP_024933309.1\|2006934_2007732_+\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133378
NZ_CP013850.1\|WP_024933465.1\|2016042_2016537_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013850.1\|WP_024933466.1\|2015385_2016000_+\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
NZ_CP013850.1\|WP_024933469.1\|2012126_2012867_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP013850.1\|WP_024933467.1\|2014708_2015062_-\|aminopeptidase-P-family-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|379790
NZ_CP013850.1\|WP_024933387.1\|2000504_2000972_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP013850.1\|WP_075143158.1\|2010407_2010929_-\|DUF4825-domain-containing-protein	unknown	unknown	gnl\|CDD\|379767
NZ_CP013850.1\|WP_012047739.1\|1999305_2000337_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|369561
NZ_CP013850.1\|WP_024933308.1\|2007828_2009826_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|239241
NZ_CP013850.1\|WP_024933311.1\|2005969_2006419_+\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
NZ_CP013850.1\|WP_024933463.1\|2019037_2019436_+\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl\|CDD\|367635

Protein	Function_ID	Function_description	E-value
NZ_CP013850.1\|WP_024933470.1\|2011229_2012120_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	4.49398e-30
NZ_CP013850.1\|WP_024933468.1\|2012969_2014376_-\|peptide-MFS-transporter	gnl\|CDD\|340904	cd17346, MFS_DtpA_like, Dipeptide and tripeptide permease A (DtpA)-like subfamily of the Major Facilitator Superfamily of transporters. The DtpA-like subfamily includes four Escherichia coli proteins: dipeptide and tripeptide permeases A (DtpA, TppB or YdgR), B (DtpB or YhiP), C (DtpC or YjdL), and D (DtpD or YbgH). They are proton-dependent permeases that transport di- and tripeptides. DtpA and DtpB display a preference for di- and tripeptides composed of L-amino acids. DtpC shows higher specificity for dipeptides compared to tripeptides, and prefers dipeptides containing a C-terminal lysine residue. The DtpA-like subfamily belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.15717e-120
NZ_CP013850.1\|WP_024933386.1\|2001051_2001507_-\|hypothetical-protein	gnl\|CDD\|378897	pfam12638, Staygreen, Staygreen protein. This family of proteins have been implicated in chlorophyll degradation. Intriguingly members of this family are also found in non-photosynthetic bacteria.	3.11653e-82
NZ_CP013850.1\|WP_024933462.1\|2019448_2020198_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	3.68348e-77
NZ_CP013850.1\|WP_024933464.1\|2016868_2019019_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	4.54862e-98
NZ_CP013850.1\|WP_024933385.1\|2004182_2005103_+\|PhzF-family-phenazine-biosynthesis-protein	gnl\|CDD\|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	3.61966e-89
NZ_CP013850.1\|WP_024933384.1\|2005414_2005831_-\|carboxymuconolactone-decarboxylase-family-protein	gnl\|CDD\|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	1.38783e-13
NZ_CP013850.1\|WP_011986682.1\|2002365_2003859_-\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	4.97681e-118
NZ_CP013850.1\|WP_024933309.1\|2006934_2007732_+\|MerR-family-transcriptional-regulator	gnl\|CDD\|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	3.17835e-15
NZ_CP013850.1\|WP_024933466.1\|2015385_2016000_+\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	2.33547e-98
NZ_CP013850.1\|WP_024933469.1\|2012126_2012867_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.74376e-12
NZ_CP013850.1\|WP_024933467.1\|2014708_2015062_-\|aminopeptidase-P-family-N-terminal-domain-containing-protein	gnl\|CDD\|379790	pfam16189, Creatinase_N_2, Creatinase/Prolidase N-terminal domain.	2.05273e-11
NZ_CP013850.1\|WP_024933387.1\|2000504_2000972_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	8.47285e-15
NZ_CP013850.1\|WP_075143158.1\|2010407_2010929_-\|DUF4825-domain-containing-protein	gnl\|CDD\|379767	pfam16107, DUF4825, Domain of unknown function (DUF4825). This domain forms the N-terminal, extracellular domain of some homologs of Staph BlaR1 proteases, where it replaces the penicillin-binding domain of BlaR1. It is also found in many uncharacterized proteins in a broad range of bacteria. Its association with BlaR1 homologs suggests it may be involved in substrate-, possibly antibiotic-binding, but this prediction has not been verified experimentally.	6.12195e-25
NZ_CP013850.1\|WP_012047739.1\|1999305_2000337_+\|alpha/beta-hydrolase	gnl\|CDD\|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	4.63467e-90
NZ_CP013850.1\|WP_024933308.1\|2007828_2009826_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|239241	cd02931, ER_like_FMN, Enoate reductase (ER)-like FMN-binding domain. Enoate reductase catalyzes the NADH-dependent reduction of carbon-carbon double bonds of several molecules, including nonactivated 2-enoates, alpha,beta-unsaturated aldehydes, cyclic ketones, and methylketones. ERs are similar to 2,4-dienoyl-CoA reductase from E. coli and to the old yellow enzyme from Saccharomyces cerevisiae.	0
NZ_CP013850.1\|WP_024933311.1\|2005969_2006419_+\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	4.0619e-36
NZ_CP013850.1\|WP_024933463.1\|2019037_2019436_+\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	5.57512e-09

>NZ_CP013850.1|WP_024933308.1|2007828_2009826_+|FAD-dependent-oxidoreductase
MKDKYKVLYDPIKIGKLEIKNRYVLAPMGPGGMCNADGSFNKRGIEFYVERAKGGTGLIMTGVTMVENNIEKCALPSMPCPTINPLNFITTGNEMTERVHAYGAKIFLQLSAGFGRVSIPSIVGKVAVAPSKIPHRFLPGVTCRELTTEEVKEYVKAFGESAEIAKKAGFDGVEIHAVHEGYLLDQFAISFFNHRTDEYGESLENRLRFACEVVQEIKKRCGQDFPVSLRYSIKSFIKDWCKGGLPDEEFEEKGRDIPEGIEAAKILVAAGYDALNGDVGSYDSWYWSHPPMYQKKGLYLPYNEILKKVVDVPIITAGRMEDPELSSDAILSGKTDMIALGRPLLADAEIPNKIFEDKYDKVRPCLSCQEGCMGRLQNFATVSCAVNPACGREKEYGLKKAEQIKKVLVVGGGVAGMEAARVAAVRGHKVTLIEKNGYLGGNIVPGGIPDFKDDDRALVKWYEGILKDLGVEIKLNVDASKENIKEFGADEVLLATGSSPRTLTIEGADKVYSAEDVLMERKNVGEKVIVIGGGLVGCETALWLKQQGKEVTIVEMQNDILQVGGPLCHANHDMLVDLIKFNKIDVKTSSYISKKTDEGFVLNTNGEESIINADSAVVAIGYLSEKDLYSEVRFDIPNARLIGDANKVQNIMYAIWSAYEVAKNI
>NZ_CP013850.1|WP_024933309.1|2006934_2007732_+|MerR-family-transcriptional-regulator
MRYSITDLAEILGCTTSAIHYFEKEHLIEVEKGKNGHRYYNVVDVFRLLSYTKYRSMEIPMKTIIAQFGGEENNYKLIEKRETMYQLEALKRAQYYMNLADAIEEHLVSIRRIEELLNKYEFAKSPEVTIMCDDECGWLSKKRSSQKIIHEWVKAMPTVQLGVFDSRMGMSNFGYLVKTKKREELELPLGLHAKELKSTSCIHTIVMADEDFTQQPQKVFKKASEFVIKKGLEIGEIAWGKILLVEVEKGAKLHPYIELWISIKM
>NZ_CP013850.1|WP_024933310.1|2006593_2006887_+|hypothetical-protein
MNFFTLNILIGAMAFIINKINNMSQDIDPFEAFNDIEENLDEIDNEKVTNFVNGLINASMSNPSIGYFFMFLVYMTPILNLLLLIKGIVNYFNREAG
>NZ_CP013850.1|WP_024933311.1|2005969_2006419_+|Lrp/AsnC-family-transcriptional-regulator
MKLDEIDVLILQELQKDSRLSIRELSKRINLSPPSVTERVRRLEDDGVIEKYTIKINKKKLGLSIDCIVKVTMKNGQYEKFKIFIKEYKRSEWCYRIAGDGCFLVKLLVKSLNDIEEFINDISSYAITETIIAFSEVTINNGINKFLGE
>NZ_CP013850.1|WP_024933384.1|2005414_2005831_-|carboxymuconolactone-decarboxylase-family-protein
MAKITFSQEGLTPFQQLLGHNKYIMEKWTSLEECFFNSNTFTHELKEEVRRTLAFNNGCQYCMSKGKPSNEITNSKILIATKIADIISKNQLIDNECFNRLKNEFSDNEVSELLALICFITASQKFGALLDLQPSCSI
>NZ_CP013850.1|WP_024933385.1|2004182_2005103_+|PhzF-family-phenazine-biosynthesis-protein
MRKFEYTLVDVFTNQVFGGNQLAVFKDAEKLSSEEMQSIARELNFSETTFVTDIGPNHKKLRIFTPKTELPMAGHPTIGTAFVLADEGVIETREGINKLIFEEGVGEIAVSIHVEGGRIRSIEMEQPMPVFGRVFGDIRTAAELLSLDIADIDTTSPIQTVSTGVPFLYIPLKSLDGISKIKLRLDTWEKFFSASEDTKHIFAFTRETLHAGSTIHSRMFAPAMGIVEDPATGGASGPLGAYLVEHGLVAHGYDGKYMIINEQGIEMGRPSFINITVSKTYNNFSEIKIGGTCVKFGAGVIELPTL
>NZ_CP013850.1|WP_011986682.1|2002365_2003859_-|PLP-dependent-aminotransferase-family-protein
MNIKIDKNSLITITQQLVHYFSDRIMSEFIKAGQKLPSIRNLAKELGISPMTIIKAYNNLEQNGLVTTIQGKGTYVNERNSTVKSNNITEKDSFQWQMSVPDYLSRSQFRYNPNLSYSNDYYNLSVASLNHKLLPTKTILKDSLSLIQNDIKLLSQYPPAQGDYEFRNIMSQYLRSKEIATSPENILVTSGSQQGISLIASTFIGPGDIVVMETPTYPGAIDLFKCRGAVILTVPVDSEGMRTDILMNLCDKHSPKLIYTIPNFHNPTGYSMSSNRKAELLDIARYNDILIVEDDPWNEISYKREKIKSIKSMDTDGHVVYIKSLSKILGPSYRLAVIISESSILSRLIAAKSNHDLGTSVLIQKTIINFIQSNKITYYIENLNKQLVKRRDKVISLLKSHAPSGMKWAIPEGGINIWVTLPKNFNVEKLLSYSITTKNISFLPGTICYPNEVEFNNLRICFTYLDEEFIEDTIIELCNLIKLLYTTKNITDYRPII
>NZ_CP013850.1|WP_024933386.1|2001051_2001507_-|hypothetical-protein
MSKLNPEKLSVEFRDGVTGTEPILGRRYTLTHSDITAELFLTIGLTYAYDKIDVMRDEVLGEWIEKEKNYLFHVYLHVDGNNPIVTGVRNHIFRRELHLALEAIRYGDRKFFISHPKLDNSPVIVHFISSYPSFDRIEKWGTFSDYSLKKR
>NZ_CP013850.1|WP_024933387.1|2000504_2000972_+|helix-turn-helix-transcriptional-regulator
MSLGEKLLYLRKKEGLSQEDVAEKLSVSRQTVSKWETDQTVPELNKAKLLSELYNVSYDYLISENYISGDVTGIEMIVDEIDWTGAWSKKYSILASYPGIKGINTYSEKISELYDSFKNDFGFNDTDTVLVLKDILYQKYKMEKKKKVDNSKEKI
>NZ_CP013850.1|WP_012047739.1|1999305_2000337_+|alpha/beta-hydrolase
MKKVIKVVSVILVILVIAGFFIIKNLTETKDGKLNMYVAANLQLYKILNPKSLNNKSIEETRGALNKQSTRWSNKPIPFSNIKNLDIKMNNEKIPVRIYTPEKGSNFPIIIYSHGGFWIGGNVDTIDGVCRKLSQNTKAIVISVNYRLAPENPFPAGLNDVYNVLQWTYKNGKSINGDEKHIAVVGDSAGGNLSAAVSSMSRDKNGPSITCQVLIYPSTNIFKLNSKSWSHFSNSFNVSTEDMEKYISIYAPKKEDRKSPYASPLLSKDLRKLPDTLVVTAEIDPLRDEGEAYANKLKESGVKAEVTRYKGITHGFITMDKITNKADEALNQISLYIQKEFQK
>NZ_CP013850.1|WP_075143158.1|2010407_2010929_-|DUF4825-domain-containing-protein
MKNKLKVLIPLIIILSLNLVGCGMNSEKKSKENIKNSSKVETYDLIKYKGTYVGDNSSVGSIIKNLPANEYSAGFILQTSKEPYEITVNYKANENLGEENYNKFWKGNKVEKLLEKNAAVLLSLIPNAEIIKFNVENIGKESYKYDRKNLEQKYGNLKNLFKDNDSLNKFLNN
>NZ_CP013850.1|WP_024933470.1|2011229_2012120_+|AraC-family-transcriptional-regulator
MNYRKDIENCIDYIEEHIKEPLTLKEITQEIGYSSYHFCRVFSFLKGMPLMEYVRKRRLSLSTIDLLEGQKIIDVAFKWGFETPSSFARAFRKEFGCSPSQYIKKMKSYYKSEGILTVGNFMIDPYIIKKEAFKVAGYGIKTNVADSKYTKDVASFWSNYNGENLESKLYKILSPLKHGEVGLCIPCSDSGDITYLLGVIVEDFSKVTSDMITVEVPKAQYAVFTTNPVNTVDNKDQREFAKIIKESWKYIFDEWFKNNDYEYDEEKLDFEFYDERCHLRPDTVMDIYVPIKKLER
>NZ_CP013850.1|WP_024933469.1|2012126_2012867_+|class-I-SAM-dependent-methyltransferase
MINYYGSLCTVMYELLHPHAPEDELQFYLQYAKKEIKILEPLCGSGRFLVPFLERGFNITGFDMSEEMLKELYKKAPKAKVFQSSIEEFSPKEKYDYIFITSGSFSLFLDEDIAFNVLVKMKEALAPKGKFVFAAETTANIIPDREEYLENCHVKTKEGYDIIFKSKSFYDKHKKILSTPSLYELYDGDNLLGKEEMDFRIKLYDSGELEELILKAGFKGSHVFSDFNRRESIDRNTEIFLYKCYI
>NZ_CP013850.1|WP_024933468.1|2012969_2014376_-|peptide-MFS-transporter
MSEKKQKHPIGLWLVNISIALQSYAAYAVVSILILFLTADVSKNGLGLSVSKAAAIIGLYQGINYMGSLVGGYITDKWLGIQKSLILGCFLTACGYLALFFAKPNIGSVWLGLIILIVAGAFFKAQISSLVGELYGKNELSKKDAAYSIFYMFINIGAFFGPIIAGLISDKWFAKVAADGEIAAYGYKYIFLMCTLIMIFIGIFIWIVSPKWLGEIGKYPVSKDKKTSTESVSTKSTEKAKAQPLTQLEKNRIKAMIVMFVFVIIFWSAWDQTATSFSLLANKLVNRTIGGFTMPVPWLTSINAIFCVVLSPIIANIWLKLGNSKKGDLSVPTKMGLGMILTGIAFLTLILGISTLGGVLDGSKQMNILFIIVAYFLLTVGELCLSPIGMAMFNKLAPAKYGSLAMGAWYLSFFFSSIISGKLAGFTDTLGYTQIFGLISGIVIVFGVILILLRNGLLKLMSLDELDK
>NZ_CP013850.1|WP_024933467.1|2014708_2015062_-|aminopeptidase-P-family-N-terminal-domain-containing-protein
MHLFINKNKLSDEIKSSLKKNAALFIHPYNKIYKEVKKFTNSDVVLVHPDRINYELYNNIDKEVITEISSSNKLDAFPAEQGRFICPSFEPISSFGEHVTIVTCIFLMENSFMVVTV
>NZ_CP013850.1|WP_024933466.1|2015385_2016000_+|sugar-O-acetyltransferase
MNQKDRMLAGLPYKACLDGLPEERMANKKKIYEYNHCFPDEHEKIHKLIRDILGKAGADVHIESPFYCDYGKNIQVGDNFFANYNCTILDVGKVIIGNNVQFAPNVSLYTAGHPIHPDSRNSGYEYGIGITIGDNVWLGGNVVVNPGVHIGNNVVIGSGSVVTKDIPDNVIAIGNPCKVIREITEEDRKYYYKNYEFDVDDYKE
>NZ_CP013850.1|WP_024933465.1|2016042_2016537_+|hypothetical-protein
MILAIECFIACVLFTLMILPSLYKEPMKHIMSYPTEIRKRVESLPQYKDAIQKKEKKHLTVKIIAVFMFAIIFAVVAYFSGAKSFSKAYIHVFTLFFVVNIYDMIVLDIGLFCHSKKTRIPGTEDMDKEYRNPWHHIKGAGIGTIIGAVVALLSGGMVHFISII
>NZ_CP013850.1|WP_024933464.1|2016868_2019019_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MHICYKSLLYSFLRYVESIDKAMYKENAFKLKDKLLNPILQESYELVTKNIKKKKCKDGTFRLMNIFSNINDSKRKKFNLLKEIDINRYDNILKENGEEIDKAYCINYVKSIIKKLLQNDNEKIYFLMSKYCSNVPFINSKNCDISLFDIAKVTAAIATCKEKNKEEYILIKGDFSGIQSFIFKTSSDGALKTLKGRSVYLTLLQEICAKYIVKELGLSLCNILYSGGGNFYILASKSDENKIKLLRKQLSKLILKAYNGEIYLALGYLSFKEEDFKNFNILWKNIGEEVGFLKSKRWSELNLKESFNEIFGPLDLGGRREHSCRLCGCINKNLKEGMCDLCISFKDFSMEMKKANFYCEKIIPKADISLHNNVKDIFHELGFEIKFSDKPLKGFKNYIINSCDFEAYDGFIFKSVKLSDESLDYMVQKQKGNNKVGVIKLDIDNLGKLFINGLGNEGSISKIISLSRNISMFFEGYIENILYKSKRLDKLKEYLKTSDWEKRVTIIFSGGDDTFIIGRYEEILEFALLIREVFEEFVGGEQLTFSAGIGIFDYNYPVINIAEDTERCLELAKNHIEGNEIYAKKNKVCIMGQVFTWNEFLEIIKLKNLIEEIYLLSSKKSIFEKINKSTLGFKAVVEGGKRLNYIKLHRLAYYLRDLNNASNKNLKNKVEELIEFYEELCLKAFMGNNKKNYNINNIMIIPVASKLAQYNYRIIN
>NZ_CP013850.1|WP_024933463.1|2019037_2019436_+|type-III-A-CRISPR-associated-protein-Csm2
MEKDYKTDKFREYEEYFKKNVLTLDKINYDQFIEKSKDYSRLLKNNGLTTSMIRKIYNEILKANEAIDLKRLRPILAYTYGRNRVKGLQSLFYTLDDLLKRLNLKTNYLEIENVKEFLEVIIAYMKFYGDRY
>NZ_CP013850.1|WP_024933462.1|2019448_2020198_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MNLLMGKIFIDGDIILKTGLRIGGGNNSIEIGGIDNNVIKNHRGEPYIPGSSLKGKLRSLLEISTNRLKDGRPCNCGECSICSIFGVGANENKQNLPTRIIVRDAFLNEDIKKQMYEKQGQFKRLELNYTESKYENTIDRLNSKATPRLIERVPEGASFRLQIIYSVFNNKDIDNFNDLIKGMKLLEDDYLGSNGSRGYGQVEFDNLNIKIKVIKDYKTKEVLNKSSLTDIDSVCLKEKLNELIEIKGV

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Crispr_ID: NZ_CP013850_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP013850_3

2024554-2024650

TypeIII

III-B

Consensus_repeat	Method
ATTGAACATTAACATGAGATGTATTTAAAT	CRISPRCasFinder

1 spacers

csx1,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10

The CRISPR arrays of NZ_CP013850_3

>merge|NZ_CP013850|3|2024554-2024650|CRISPRCasFinder
GTTGAACCTTAATATGGGATGTATTTAAATTTTTCTTAACTTCCTTAAATGCTTACATATTCTTTGATTGAATATTAACATAGGATGTATTTAAGCA

>NZ_CP013850|3|3|2024554-2024650|CRISPRCasFinder
GTTGAACCTTAATATGGGATGTATTTAAAT	TTTTCTTAACTTCCTTAAATGCTTACATATTCTTTG
ATTGAATATTAACATAGGATGTATTTAAGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP013850.1\|WP_024933148.1\|2029138_2029540_+\|membrane-protein	unknown	unknown	unknown
NZ_CP013850.1\|WP_075143157.1\|2020199_2021255_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	cd09663_csm4gr5_CAS-III-A	gnl\|CDD\|380071
NZ_CP013850.1\|WP_075143155.1\|2022338_2023820_+\|hypothetical-protein	csx1	mkCas0109_csx1_CAS-III	gnl\|CDD\|187878
NZ_CP013850.1\|WP_003358211.1\|2031278_2032643_+\|PTS-ascorbate-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|236502
NZ_CP013850.1\|WP_075143154.1\|2023836_2024526_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273848
NZ_CP013850.1\|WP_024933464.1\|2016868_2019019_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
NZ_CP013850.1\|WP_024933145.1\|2025805_2026294_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227595
NZ_CP013850.1\|WP_024933147.1\|2028054_2028801_+\|cell-envelope-integrity-protein-TolA	unknown	unknown	gnl\|CDD\|236545
NZ_CP013850.1\|WP_024933149.1\|2032854_2034948_+\|transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP013850.1\|WP_024933467.1\|2014708_2015062_-\|aminopeptidase-P-family-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|379790
NZ_CP013850.1\|WP_024933465.1\|2016042_2016537_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013850.1\|WP_024933466.1\|2015385_2016000_+\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
NZ_CP013850.1\|WP_011986654.1\|2030515_2030953_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|238129
NZ_CP013850.1\|WP_024933146.1\|2027121_2027715_+\|glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl\|CDD\|172889
NZ_CP013850.1\|WP_024933462.1\|2019448_2020198_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NZ_CP013850.1\|WP_011986655.1\|2029775_2030492_+\|transaldolase	unknown	unknown	gnl\|CDD\|183481
NZ_CP013850.1\|WP_021134329.1\|2035273_2035627_+\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|379915
NZ_CP013850.1\|WP_003361919.1\|2030981_2031266_+\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99905
NZ_CP013850.1\|WP_075143156.1\|2021244_2022336_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|273863
NZ_CP013850.1\|WP_024933463.1\|2019037_2019436_+\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl\|CDD\|367635

Protein	Function_ID	Function_description	E-value
NZ_CP013850.1\|WP_075143157.1\|2020199_2021255_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl\|CDD\|380071	pfam17953, Csm4_C, CRISPR Csm4 C-terminal domain. Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci play a pivotal role in the prokaryotic host defense system against invading genetic materials. The CRISPR loci are transcribed to produce CRISPR RNAs (crRNAs), which form interference complexes with CRISPR-associated (Cas) proteins to target the invading nucleic acid for degradation. The interference complex of the type III-A CRISPR-Cas system is composed of five Cas proteins (Csm1-Csm5) and a crRNA, and targets invading DNA. This entry represents the C-terminal domain found in Csm4. Csm4 structurally resembles Cmr3, a component of the type III-B CRISPR-Cas interference complex. Studies indicate that Csm3-Csm4 complex binds single-stranded RNA in a non-sequence-specific manner. Structural analysis show, Csm3 and Csm4 have one and two ferredoxin-like folds (also known as an RRM-like fold), respectively. The long beta-hairpin inserted into the C-terminal ferredoxin-like fold of Csm4, is well-conserved in the Cmr3 structure. The corresponding beta-hairpin of Cmr3 binds the D1 domain of Cmr2, as observed in the Cmr2-Cmr3 complex structure. Furthermore, it is suggested that the hairpin of Csm4 is responsible for the interaction with Csm1 (ortholog of Cmr2).	3.43304e-17
NZ_CP013850.1\|WP_075143155.1\|2022338_2023820_+\|hypothetical-protein	gnl\|CDD\|187878	cd09747, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as Cas02710 family.	3.51889e-09
NZ_CP013850.1\|WP_024933147.1\|2028054_2028801_+\|cell-envelope-integrity-protein-TolA	gnl\|CDD\|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	1.38627e-11
NZ_CP013850.1\|WP_024933146.1\|2027121_2027715_+\|glycerol-3-phosphate-acyltransferase	gnl\|CDD\|172889	PRK14413, PRK14413, glycerol-3-phosphate acyltransferase.	4.80542e-92
NZ_CP013850.1\|WP_003358211.1\|2031278_2032643_+\|PTS-ascorbate-transporter-subunit-IIC	gnl\|CDD\|236502	PRK09410, ulaA, PTS system ascorbate-specific transporter subunit IIC; Reviewed.	0
NZ_CP013850.1\|WP_024933464.1\|2016868_2019019_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	4.54862e-98
NZ_CP013850.1\|WP_024933145.1\|2025805_2026294_-\|hypothetical-protein	gnl\|CDD\|227595	COG5270, COG5270, PUA domain (predicted RNA-binding domain) [Translation, ribosomal structure and biogenesis].	0.00379916
NZ_CP013850.1\|WP_075143154.1\|2023836_2024526_+\|hypothetical-protein	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	0.00384193
NZ_CP013850.1\|WP_024933149.1\|2032854_2034948_+\|transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	5.72803e-58
NZ_CP013850.1\|WP_024933467.1\|2014708_2015062_-\|aminopeptidase-P-family-N-terminal-domain-containing-protein	gnl\|CDD\|379790	pfam16189, Creatinase_N_2, Creatinase/Prolidase N-terminal domain.	2.05273e-11
NZ_CP013850.1\|WP_024933466.1\|2015385_2016000_+\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	2.33547e-98
NZ_CP013850.1\|WP_011986654.1\|2030515_2030953_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	9.05568e-38
NZ_CP013850.1\|WP_024933462.1\|2019448_2020198_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	3.68348e-77
NZ_CP013850.1\|WP_011986655.1\|2029775_2030492_+\|transaldolase	gnl\|CDD\|183481	PRK12376, PRK12376, putative translaldolase; Provisional.	3.52947e-157
NZ_CP013850.1\|WP_021134329.1\|2035273_2035627_+\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|379915	pfam17032, zinc_ribbon_15, zinc-ribbon family. This zinc-ribbon region is found on a set of largely microsporidia-specific proteins.	0.000183435
NZ_CP013850.1\|WP_003361919.1\|2030981_2031266_+\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|99905	cd05563, PTS_IIB_ascorbate, PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a transmembrane channel IIC subunit. Subunits IIA, IIB, and IIC are encoded by the sgaA, sgaB, and sgaT genes of the E. coli sgaTBA operon. In some bacteria, the IIB (SgaB) domain is fused C-terminal to the IIA (SgaT) domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include ascorbate, chitobiose/lichenan, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	2.52704e-28
NZ_CP013850.1\|WP_075143156.1\|2021244_2022336_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|273863	TIGR01899, cas_TM1807_csm5, CRISPR type III-A/MTUBE-associated RAMP protein Csm5. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm5, for CRISPR/cas Subtype Mtube, protein 5.	3.88011e-18
NZ_CP013850.1\|WP_024933463.1\|2019037_2019436_+\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	5.57512e-09

>NZ_CP013850.1|WP_075143154.1|2023836_2024526_+|hypothetical-protein
MHYYQLKIRVKLENNINYIQAPYLIGTFINNCMLKNDMLKNIHKKKIYKYVYDSFFPIEKDGIYKREKYYNIQLRTINLNLINKLAIALYNHKFNGIKTVNIDLEVMEPTKINQLYTLKPSIVTITGQPWIKNKHSIDVLIGNLNANLEKKYKQIFNEELENNKSFIKKIKVVNNIPIKYEYKNIILLGNKFEIIVNEDEVSQRKATIALGMGLGEKGSSLGAGFCIYR
>NZ_CP013850.1|WP_075143155.1|2022338_2023820_+|hypothetical-protein
MDNVLIINLGNSDIEKEGNKIEFGEFREKTKKIYEQLEGANKEEKQEIFKYLDFPIIKAIIDKVDGELKNEKLDKVILAYTNQKFNNNKDTVYLYEILKQKKHLVNNLETDNQDIWEKRLKETNFKQSYNIDFDPSDIDRMYNFYAEEINELNNKKIKKLFFSITGGASAMNFALLINAIEKFSGQLIPCYLSRGKKVAYKVNIAKNLRKQILKRDIKILINNKDYFAAIKMLENLEDGIVDDMSKLELKNIILALKYAEARIQFNFDKCKEYGEKCLDNTAEYREEFSQAVKDILIEKDDYINRLVELKNNAIYLYKKGSYTDFLGRVYRFQEAVYEHILGQYDLIIEKSNGVKINKEILKSRYSDKKEILDNIKIAGNKLEYEKNLTVDAMSKIISTLIDNDDVRNIVNRMEEIKDVKQLRNKSILAHGFEGISKEKIQGKLNCEEKDISKLLEEVMCKILVLFKIGTIEDMFYCENSRYDCILIEMIEKL
>NZ_CP013850.1|WP_075143156.1|2021244_2022336_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MNYDKIILNLKGQVLTPVHIGCGKKYSPYLDIIKNENKITVLDEEKIIEKLVLNDEIFEEYINILKNKSPNAIEKYNIINILKNNKIEIGEVKKYDLICGNSFNNLIDVNQSIKTKGIPYIPGSSIKGSIRTALIYNKLLKNGIDFGKIKEISNLKNKYYCYLGQDIFRQNDKLIYDDMMKNLLVRDTDIISNNKVKVYLCRAVNLYESIKNGNISTSVKSLNECIEEYTDFTFSIIIKNSLISKEELYNNINSFYEKILLKEIQEIEKLKLNIINSQYKLLLNEINEFRKYNNGFILRIGGMKGIFSNTIDSILSKKELEDIRNAHKNKRKKTGEFPTTKWCVMDEYENIKTTLGWIKIMEE
>NZ_CP013850.1|WP_075143157.1|2020199_2021255_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MKKVILKIDNETKFHIGNGQEILEYIPSDKLYSAIINSLALTYSKYELNKLIEIINEKLQISSAFMGIKIKNKNKGIEKSIDFLPRPYMYIGNNNIISTQLLNRKKFKKINYVSNNVFLDFNKHYDSKKNFINYDFQQGYIIGEKYYVTDREINFLSEDEKKYLEKYKPIINESVQRNYINRFSKESIGTYYDNFKVIVQEKYKDMQLIPYFYFYIKGDLEIDKIMYAIIEGGIGGKRSLGAGTIKDISIEECDDFKENGERFINISMIYPDKQELNYIESYALENRNGYIYSQGPTDLKKPWIRMIKEGGVFTKRIKGNINDINVKDIDYPIYTYGKAFFITLGGNLDEL
>NZ_CP013850.1|WP_024933462.1|2019448_2020198_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MNLLMGKIFIDGDIILKTGLRIGGGNNSIEIGGIDNNVIKNHRGEPYIPGSSLKGKLRSLLEISTNRLKDGRPCNCGECSICSIFGVGANENKQNLPTRIIVRDAFLNEDIKKQMYEKQGQFKRLELNYTESKYENTIDRLNSKATPRLIERVPEGASFRLQIIYSVFNNKDIDNFNDLIKGMKLLEDDYLGSNGSRGYGQVEFDNLNIKIKVIKDYKTKEVLNKSSLTDIDSVCLKEKLNELIEIKGV
>NZ_CP013850.1|WP_024933463.1|2019037_2019436_+|type-III-A-CRISPR-associated-protein-Csm2
MEKDYKTDKFREYEEYFKKNVLTLDKINYDQFIEKSKDYSRLLKNNGLTTSMIRKIYNEILKANEAIDLKRLRPILAYTYGRNRVKGLQSLFYTLDDLLKRLNLKTNYLEIENVKEFLEVIIAYMKFYGDRY
>NZ_CP013850.1|WP_024933464.1|2016868_2019019_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MHICYKSLLYSFLRYVESIDKAMYKENAFKLKDKLLNPILQESYELVTKNIKKKKCKDGTFRLMNIFSNINDSKRKKFNLLKEIDINRYDNILKENGEEIDKAYCINYVKSIIKKLLQNDNEKIYFLMSKYCSNVPFINSKNCDISLFDIAKVTAAIATCKEKNKEEYILIKGDFSGIQSFIFKTSSDGALKTLKGRSVYLTLLQEICAKYIVKELGLSLCNILYSGGGNFYILASKSDENKIKLLRKQLSKLILKAYNGEIYLALGYLSFKEEDFKNFNILWKNIGEEVGFLKSKRWSELNLKESFNEIFGPLDLGGRREHSCRLCGCINKNLKEGMCDLCISFKDFSMEMKKANFYCEKIIPKADISLHNNVKDIFHELGFEIKFSDKPLKGFKNYIINSCDFEAYDGFIFKSVKLSDESLDYMVQKQKGNNKVGVIKLDIDNLGKLFINGLGNEGSISKIISLSRNISMFFEGYIENILYKSKRLDKLKEYLKTSDWEKRVTIIFSGGDDTFIIGRYEEILEFALLIREVFEEFVGGEQLTFSAGIGIFDYNYPVINIAEDTERCLELAKNHIEGNEIYAKKNKVCIMGQVFTWNEFLEIIKLKNLIEEIYLLSSKKSIFEKINKSTLGFKAVVEGGKRLNYIKLHRLAYYLRDLNNASNKNLKNKVEELIEFYEELCLKAFMGNNKKNYNINNIMIIPVASKLAQYNYRIIN
>NZ_CP013850.1|WP_024933465.1|2016042_2016537_+|hypothetical-protein
MILAIECFIACVLFTLMILPSLYKEPMKHIMSYPTEIRKRVESLPQYKDAIQKKEKKHLTVKIIAVFMFAIIFAVVAYFSGAKSFSKAYIHVFTLFFVVNIYDMIVLDIGLFCHSKKTRIPGTEDMDKEYRNPWHHIKGAGIGTIIGAVVALLSGGMVHFISII
>NZ_CP013850.1|WP_024933466.1|2015385_2016000_+|sugar-O-acetyltransferase
MNQKDRMLAGLPYKACLDGLPEERMANKKKIYEYNHCFPDEHEKIHKLIRDILGKAGADVHIESPFYCDYGKNIQVGDNFFANYNCTILDVGKVIIGNNVQFAPNVSLYTAGHPIHPDSRNSGYEYGIGITIGDNVWLGGNVVVNPGVHIGNNVVIGSGSVVTKDIPDNVIAIGNPCKVIREITEEDRKYYYKNYEFDVDDYKE
>NZ_CP013850.1|WP_024933467.1|2014708_2015062_-|aminopeptidase-P-family-N-terminal-domain-containing-protein
MHLFINKNKLSDEIKSSLKKNAALFIHPYNKIYKEVKKFTNSDVVLVHPDRINYELYNNIDKEVITEISSSNKLDAFPAEQGRFICPSFEPISSFGEHVTIVTCIFLMENSFMVVTV
>NZ_CP013850.1|WP_024933145.1|2025805_2026294_-|hypothetical-protein
MISKKIIAFIAMTIMMISLLIGCSNNTMDKVYNDNIKIASVYDTFGLDKSDEIIESGIYKGKLKLSGSGTIWTYESSSDFDLKVPYILSVKSGKAKIVLISPDNTVVNLVENTDKATMKGTTSLTLPIKKGNNRIKLVGYKKADIDIELHIEKGTFEKISFN
>NZ_CP013850.1|WP_024933146.1|2027121_2027715_+|glycerol-3-phosphate-acyltransferase
MIIIITSIISFLLGSIPTGYFITKKTCGIDIRTKGSGNIGSTNVKRIVGTKISIITQTIDVLKGIIPVVLGISLSKIVKLPVSIDTYLSIIAIAAILGHDYTPFLKFKGGKGVNTTLGVFIFIAPIPTLTGLAVYFILGLFIRIVSIRSISIGITIPIMCIITKLPIQIIISTTIACILMIIRHKDNLVRLIRGEEK
>NZ_CP013850.1|WP_024933147.1|2028054_2028801_+|cell-envelope-integrity-protein-TolA
MDKFRNMKKSHIALLVIMYMVLMGSLPRFTGWATIFSAIAVGGYFLKNKKDLKELTRKKKNFIFAGIIILAIIGSFNVAVGNNIQNEKLLAEKSKQEQQIKKEQEEKKLAEEQKRIQEEEARKKAEEEKRKQEEEAKKKTEEEAKKKALEEQKKQEELKRKQEEENKVKAENEQAQAAFAQSTGKGDSNSQSNESQNADDNQNYTVYKTRTGSKYHSSGCRYLKKSCYETTVSQARNEGLTPCRVCNP
>NZ_CP013850.1|WP_024933148.1|2029138_2029540_+|membrane-protein
MNILISTCNIGIPVLMIFIGILYKCNLYKKIDKTLDLIVPIAMFFTGFSERDREHLYKNTNKLALVNRKCSLIWSISGVCTLLLTIISLILNKSDIYNTSVILLEPEFLILVIVFITVEYVLKRNFYKKIQQS
>NZ_CP013850.1|WP_011986655.1|2029775_2030492_+|transaldolase
MKYNDLKIKIFADGADLNGMLDAYNKGIVKGFTTNPSLMKKAGITDYKEFAKEVLAKIKDMPVSFEVFSDDLETMEKEAEVLGNLGENVYIKIPVTNTKGESTAPLIKKLSEKGYHLNVTAIFTIDQVKEVVGALKSGVDSIVSVFAGRIADTGEDPVKIMKEASKICKTKEGVELLWASCREFYSIVEADKCGCEIITVTNDVLKKMPNMGKDLKEYSIETVRGFYKDASSLGFSIL
>NZ_CP013850.1|WP_011986654.1|2030515_2030953_+|PTS-sugar-transporter-subunit-IIA
MLKNYINDQVVEVNVEVKNWEEAVRLGGKLLEEDGAVEHSYIDAMVDTVKNMGPYIVIAPGIAMPHARPEAGAKNIRIGLLKLKNPVNFGNEEHDPVDMVIFLCAVDNKAHIEVLGELVQLIEDDDFLKIVRNASTKKEILDYIK
>NZ_CP013850.1|WP_003361919.1|2030981_2031266_+|PTS-sugar-transporter-subunit-IIB
MNILTVCGNGIGSSLMLAMKIEEICKENGIAANVESTDFNSAQGKKADLIVTVKELAEQFEGRDVAVVRSYINKKKITEDVLEIIKQKDEELKK
>NZ_CP013850.1|WP_003358211.1|2031278_2032643_+|PTS-ascorbate-transporter-subunit-IIC
MLGLLQFLRDVLKQPALLMGIMALVGLVALKKPGHKVLTGTLKPILGYLMLGAGADFIVANLEPLGGMIQTGFNITGVVPNNEAIVAVAQKVLGVETMSILVVGLLINLVIARFTKYKYVFLTGHHSFFMACLLSAVLGTSGMKGTELILFGGFLLGAWSAISPAIGQKYTLKVTDGDEIAMGHFGSLAYYVSAWVGSKVGKPEESTENIEIPEKWGFLRDTTISTAITMMVFYIVAAVAAGPEYVSKLSDGMSPILFAIMSSLKFAVGVTIVYNGVRMILGDLIPAFQGIATKIIPDAIPAVDCAVFFPYAPTAVIIGFVSSFIGGIIGMVLLGVAGGVLIIPGLVPHFFCGSTAGIFGNATGGKKGAVIGSFVNGLLITFAPALLLPVLSTLGFKNTTFGDFDFGVLGIIIGKTSNLAGKTGIIIIAMLMLVALIVPNFIKTKSKALNNIEE
>NZ_CP013850.1|WP_024933149.1|2032854_2034948_+|transcription-antiterminator
MLNKRCSNILQMIVNNEKPITIKEISKKVNKSPRTVRYDLDKIDDYLTEIEFPKLERKSNLGISLDLKDEEIKKLFKIIGKINNYDYVLSQKERVFYIIYELLNKSEFATINMLSDRMMVSRSTIINDLIEVKKWLSENKITLESSKGQGIKILGRERDLRRAAVKLFFQSMDSINFFNVTTLKLFNDIDIDFIRNTIKIAEEQMETSFSDDAFNNLVIHIAIAIKRIELSKDIIMDSEELKNLRKTAEYVIASGIAKMLEDRFKISIPEDEIGYITIHILGSNTSTLENIVKDDWIYLHLIVFKLIENVENITGINFSKDNKLFDSLAQHIRPAIYRLKHDIKVKNPLIEEIKEKYSYIFESIEEGVKFIEEDIGDSVNQEEIGYLTLHFMASIERSKNKKHRKPNVLIVCATGIGTSKFISNKLKSIFDINIIDTISSHTMEKILKYNKNIDLIVTTIPLKVKGIKCIEVNTFLTEKNISELGLYFAKFIRNNSEECNGSCKYEERDKVQEILNIVKENCTIHDYYKLRNKLALYLNIKDPTLTEDHKPSLKELLKPDFIKLNEEAENWEDAVRKSGEILMNNGCVKESYIDAMVNTVKNMGPYIVIAPGIAMPHAAPEDGVLKTGISMLTLKDPISFGNSEHDPVSVIISICSIDKVNHMKALKELMSIMDQEDFISKVKNIKASSEIDSILYS
>NZ_CP013850.1|WP_021134329.1|2035273_2035627_+|zinc-ribbon-domain-containing-protein
MIIWGWGKVTKKIIGAVFERTCNYCNTDEVWNLCVVRTWFTLFFIPIIPYKKQYCIACPKCWSYIELTQEEFEKIKIDITSSSNNINEKVVTDNIKYAGKTETQINYLKQMEEYSNK

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Crispr_ID: NZ_CP013850_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP013850_4

2024891-2025072

TypeIII

III-B

Consensus_repeat	Method
TTAGTCGAACAGTAACATAAGATGTATTTAAATAGAGAACTTAA	PILER-CR
ATTGAACATTAACATGAGATGTATTTAAAT	CRISPRCasFinder

2 spacers

csx1,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10

The CRISPR arrays of NZ_CP013850_4

>merge|NZ_CP013850|4|2024891-2025072|PILER-CR,CRISPRCasFinder
TATTTTACTATGGTCGAACAGTAACATAAGATGTATTTAAATAGCATATAATCAATTTTCTTACCCTTTTCAGTATGTCGAACAGTAACATAAGATGTATTTAAATTAATAATTTCATTCCTGGATCTAATTTTTGTATTAGTTGAACAGTAACATAAGATGTATTTAAGCAGAGAACTTAA

>NZ_CP013850|4|1|2024891-2025072|PILER-CR
TATTTTACTATGGTCGAACAGTAACATAAGATGTATTTAAATAGCATATAATC	AATTTTCTTACCCTTTTCAGTATGTCGAACA
GTAACATAAGATGTATTTAAATTAATAATTTCATTCCTGGATCTAATTTTTGT	ATTAGTTGAACAGTAACATAA
GATGTATTTAAGCAGAGAACTTAA

>NZ_CP013850|4|4|2024903-2025062|CRISPRCasFinder
GTCGAACAGTAACATAAGATGTATTTAAAT	AGCATATAATCAATTTTCTTACCCTTTTCAGTAT
GTCGAACAGTAACATAAGATGTATTTAAAT	TAATAATTTCATTCCTGGATCTAATTTTTGTATTA
GTTGAACAGTAACATAAGATGTATTTAAGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP013850.1\|WP_024933148.1\|2029138_2029540_+\|membrane-protein	unknown	unknown	unknown
NZ_CP013850.1\|WP_075143157.1\|2020199_2021255_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	cd09663_csm4gr5_CAS-III-A	gnl\|CDD\|380071
NZ_CP013850.1\|WP_075143155.1\|2022338_2023820_+\|hypothetical-protein	csx1	mkCas0109_csx1_CAS-III	gnl\|CDD\|187878
NZ_CP013850.1\|WP_003358211.1\|2031278_2032643_+\|PTS-ascorbate-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|236502
NZ_CP013850.1\|WP_075143154.1\|2023836_2024526_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273848
NZ_CP013850.1\|WP_024933464.1\|2016868_2019019_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
NZ_CP013850.1\|WP_024933145.1\|2025805_2026294_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227595
NZ_CP013850.1\|WP_024933147.1\|2028054_2028801_+\|cell-envelope-integrity-protein-TolA	unknown	unknown	gnl\|CDD\|236545
NZ_CP013850.1\|WP_024933149.1\|2032854_2034948_+\|transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP013850.1\|WP_024933467.1\|2014708_2015062_-\|aminopeptidase-P-family-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|379790
NZ_CP013850.1\|WP_024933465.1\|2016042_2016537_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013850.1\|WP_024933466.1\|2015385_2016000_+\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
NZ_CP013850.1\|WP_011986654.1\|2030515_2030953_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|238129
NZ_CP013850.1\|WP_024933146.1\|2027121_2027715_+\|glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl\|CDD\|172889
NZ_CP013850.1\|WP_024933462.1\|2019448_2020198_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NZ_CP013850.1\|WP_011986655.1\|2029775_2030492_+\|transaldolase	unknown	unknown	gnl\|CDD\|183481
NZ_CP013850.1\|WP_021134329.1\|2035273_2035627_+\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|379915
NZ_CP013850.1\|WP_003361919.1\|2030981_2031266_+\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99905
NZ_CP013850.1\|WP_075143156.1\|2021244_2022336_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|273863
NZ_CP013850.1\|WP_024933463.1\|2019037_2019436_+\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl\|CDD\|367635

Protein	Function_ID	Function_description	E-value
NZ_CP013850.1\|WP_075143157.1\|2020199_2021255_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl\|CDD\|380071	pfam17953, Csm4_C, CRISPR Csm4 C-terminal domain. Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci play a pivotal role in the prokaryotic host defense system against invading genetic materials. The CRISPR loci are transcribed to produce CRISPR RNAs (crRNAs), which form interference complexes with CRISPR-associated (Cas) proteins to target the invading nucleic acid for degradation. The interference complex of the type III-A CRISPR-Cas system is composed of five Cas proteins (Csm1-Csm5) and a crRNA, and targets invading DNA. This entry represents the C-terminal domain found in Csm4. Csm4 structurally resembles Cmr3, a component of the type III-B CRISPR-Cas interference complex. Studies indicate that Csm3-Csm4 complex binds single-stranded RNA in a non-sequence-specific manner. Structural analysis show, Csm3 and Csm4 have one and two ferredoxin-like folds (also known as an RRM-like fold), respectively. The long beta-hairpin inserted into the C-terminal ferredoxin-like fold of Csm4, is well-conserved in the Cmr3 structure. The corresponding beta-hairpin of Cmr3 binds the D1 domain of Cmr2, as observed in the Cmr2-Cmr3 complex structure. Furthermore, it is suggested that the hairpin of Csm4 is responsible for the interaction with Csm1 (ortholog of Cmr2).	3.43304e-17
NZ_CP013850.1\|WP_075143155.1\|2022338_2023820_+\|hypothetical-protein	gnl\|CDD\|187878	cd09747, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as Cas02710 family.	3.51889e-09
NZ_CP013850.1\|WP_024933147.1\|2028054_2028801_+\|cell-envelope-integrity-protein-TolA	gnl\|CDD\|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	1.38627e-11
NZ_CP013850.1\|WP_024933146.1\|2027121_2027715_+\|glycerol-3-phosphate-acyltransferase	gnl\|CDD\|172889	PRK14413, PRK14413, glycerol-3-phosphate acyltransferase.	4.80542e-92
NZ_CP013850.1\|WP_003358211.1\|2031278_2032643_+\|PTS-ascorbate-transporter-subunit-IIC	gnl\|CDD\|236502	PRK09410, ulaA, PTS system ascorbate-specific transporter subunit IIC; Reviewed.	0
NZ_CP013850.1\|WP_024933464.1\|2016868_2019019_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	4.54862e-98
NZ_CP013850.1\|WP_024933145.1\|2025805_2026294_-\|hypothetical-protein	gnl\|CDD\|227595	COG5270, COG5270, PUA domain (predicted RNA-binding domain) [Translation, ribosomal structure and biogenesis].	0.00379916
NZ_CP013850.1\|WP_075143154.1\|2023836_2024526_+\|hypothetical-protein	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	0.00384193
NZ_CP013850.1\|WP_024933149.1\|2032854_2034948_+\|transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	5.72803e-58
NZ_CP013850.1\|WP_024933467.1\|2014708_2015062_-\|aminopeptidase-P-family-N-terminal-domain-containing-protein	gnl\|CDD\|379790	pfam16189, Creatinase_N_2, Creatinase/Prolidase N-terminal domain.	2.05273e-11
NZ_CP013850.1\|WP_024933466.1\|2015385_2016000_+\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	2.33547e-98
NZ_CP013850.1\|WP_011986654.1\|2030515_2030953_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	9.05568e-38
NZ_CP013850.1\|WP_024933462.1\|2019448_2020198_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	3.68348e-77
NZ_CP013850.1\|WP_011986655.1\|2029775_2030492_+\|transaldolase	gnl\|CDD\|183481	PRK12376, PRK12376, putative translaldolase; Provisional.	3.52947e-157
NZ_CP013850.1\|WP_021134329.1\|2035273_2035627_+\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|379915	pfam17032, zinc_ribbon_15, zinc-ribbon family. This zinc-ribbon region is found on a set of largely microsporidia-specific proteins.	0.000183435
NZ_CP013850.1\|WP_003361919.1\|2030981_2031266_+\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|99905	cd05563, PTS_IIB_ascorbate, PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a transmembrane channel IIC subunit. Subunits IIA, IIB, and IIC are encoded by the sgaA, sgaB, and sgaT genes of the E. coli sgaTBA operon. In some bacteria, the IIB (SgaB) domain is fused C-terminal to the IIA (SgaT) domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include ascorbate, chitobiose/lichenan, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	2.52704e-28
NZ_CP013850.1\|WP_075143156.1\|2021244_2022336_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|273863	TIGR01899, cas_TM1807_csm5, CRISPR type III-A/MTUBE-associated RAMP protein Csm5. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm5, for CRISPR/cas Subtype Mtube, protein 5.	3.88011e-18
NZ_CP013850.1\|WP_024933463.1\|2019037_2019436_+\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	5.57512e-09

>NZ_CP013850.1|WP_075143154.1|2023836_2024526_+|hypothetical-protein
MHYYQLKIRVKLENNINYIQAPYLIGTFINNCMLKNDMLKNIHKKKIYKYVYDSFFPIEKDGIYKREKYYNIQLRTINLNLINKLAIALYNHKFNGIKTVNIDLEVMEPTKINQLYTLKPSIVTITGQPWIKNKHSIDVLIGNLNANLEKKYKQIFNEELENNKSFIKKIKVVNNIPIKYEYKNIILLGNKFEIIVNEDEVSQRKATIALGMGLGEKGSSLGAGFCIYR
>NZ_CP013850.1|WP_075143155.1|2022338_2023820_+|hypothetical-protein
MDNVLIINLGNSDIEKEGNKIEFGEFREKTKKIYEQLEGANKEEKQEIFKYLDFPIIKAIIDKVDGELKNEKLDKVILAYTNQKFNNNKDTVYLYEILKQKKHLVNNLETDNQDIWEKRLKETNFKQSYNIDFDPSDIDRMYNFYAEEINELNNKKIKKLFFSITGGASAMNFALLINAIEKFSGQLIPCYLSRGKKVAYKVNIAKNLRKQILKRDIKILINNKDYFAAIKMLENLEDGIVDDMSKLELKNIILALKYAEARIQFNFDKCKEYGEKCLDNTAEYREEFSQAVKDILIEKDDYINRLVELKNNAIYLYKKGSYTDFLGRVYRFQEAVYEHILGQYDLIIEKSNGVKINKEILKSRYSDKKEILDNIKIAGNKLEYEKNLTVDAMSKIISTLIDNDDVRNIVNRMEEIKDVKQLRNKSILAHGFEGISKEKIQGKLNCEEKDISKLLEEVMCKILVLFKIGTIEDMFYCENSRYDCILIEMIEKL
>NZ_CP013850.1|WP_075143156.1|2021244_2022336_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MNYDKIILNLKGQVLTPVHIGCGKKYSPYLDIIKNENKITVLDEEKIIEKLVLNDEIFEEYINILKNKSPNAIEKYNIINILKNNKIEIGEVKKYDLICGNSFNNLIDVNQSIKTKGIPYIPGSSIKGSIRTALIYNKLLKNGIDFGKIKEISNLKNKYYCYLGQDIFRQNDKLIYDDMMKNLLVRDTDIISNNKVKVYLCRAVNLYESIKNGNISTSVKSLNECIEEYTDFTFSIIIKNSLISKEELYNNINSFYEKILLKEIQEIEKLKLNIINSQYKLLLNEINEFRKYNNGFILRIGGMKGIFSNTIDSILSKKELEDIRNAHKNKRKKTGEFPTTKWCVMDEYENIKTTLGWIKIMEE
>NZ_CP013850.1|WP_075143157.1|2020199_2021255_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MKKVILKIDNETKFHIGNGQEILEYIPSDKLYSAIINSLALTYSKYELNKLIEIINEKLQISSAFMGIKIKNKNKGIEKSIDFLPRPYMYIGNNNIISTQLLNRKKFKKINYVSNNVFLDFNKHYDSKKNFINYDFQQGYIIGEKYYVTDREINFLSEDEKKYLEKYKPIINESVQRNYINRFSKESIGTYYDNFKVIVQEKYKDMQLIPYFYFYIKGDLEIDKIMYAIIEGGIGGKRSLGAGTIKDISIEECDDFKENGERFINISMIYPDKQELNYIESYALENRNGYIYSQGPTDLKKPWIRMIKEGGVFTKRIKGNINDINVKDIDYPIYTYGKAFFITLGGNLDEL
>NZ_CP013850.1|WP_024933462.1|2019448_2020198_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MNLLMGKIFIDGDIILKTGLRIGGGNNSIEIGGIDNNVIKNHRGEPYIPGSSLKGKLRSLLEISTNRLKDGRPCNCGECSICSIFGVGANENKQNLPTRIIVRDAFLNEDIKKQMYEKQGQFKRLELNYTESKYENTIDRLNSKATPRLIERVPEGASFRLQIIYSVFNNKDIDNFNDLIKGMKLLEDDYLGSNGSRGYGQVEFDNLNIKIKVIKDYKTKEVLNKSSLTDIDSVCLKEKLNELIEIKGV
>NZ_CP013850.1|WP_024933463.1|2019037_2019436_+|type-III-A-CRISPR-associated-protein-Csm2
MEKDYKTDKFREYEEYFKKNVLTLDKINYDQFIEKSKDYSRLLKNNGLTTSMIRKIYNEILKANEAIDLKRLRPILAYTYGRNRVKGLQSLFYTLDDLLKRLNLKTNYLEIENVKEFLEVIIAYMKFYGDRY
>NZ_CP013850.1|WP_024933464.1|2016868_2019019_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MHICYKSLLYSFLRYVESIDKAMYKENAFKLKDKLLNPILQESYELVTKNIKKKKCKDGTFRLMNIFSNINDSKRKKFNLLKEIDINRYDNILKENGEEIDKAYCINYVKSIIKKLLQNDNEKIYFLMSKYCSNVPFINSKNCDISLFDIAKVTAAIATCKEKNKEEYILIKGDFSGIQSFIFKTSSDGALKTLKGRSVYLTLLQEICAKYIVKELGLSLCNILYSGGGNFYILASKSDENKIKLLRKQLSKLILKAYNGEIYLALGYLSFKEEDFKNFNILWKNIGEEVGFLKSKRWSELNLKESFNEIFGPLDLGGRREHSCRLCGCINKNLKEGMCDLCISFKDFSMEMKKANFYCEKIIPKADISLHNNVKDIFHELGFEIKFSDKPLKGFKNYIINSCDFEAYDGFIFKSVKLSDESLDYMVQKQKGNNKVGVIKLDIDNLGKLFINGLGNEGSISKIISLSRNISMFFEGYIENILYKSKRLDKLKEYLKTSDWEKRVTIIFSGGDDTFIIGRYEEILEFALLIREVFEEFVGGEQLTFSAGIGIFDYNYPVINIAEDTERCLELAKNHIEGNEIYAKKNKVCIMGQVFTWNEFLEIIKLKNLIEEIYLLSSKKSIFEKINKSTLGFKAVVEGGKRLNYIKLHRLAYYLRDLNNASNKNLKNKVEELIEFYEELCLKAFMGNNKKNYNINNIMIIPVASKLAQYNYRIIN
>NZ_CP013850.1|WP_024933465.1|2016042_2016537_+|hypothetical-protein
MILAIECFIACVLFTLMILPSLYKEPMKHIMSYPTEIRKRVESLPQYKDAIQKKEKKHLTVKIIAVFMFAIIFAVVAYFSGAKSFSKAYIHVFTLFFVVNIYDMIVLDIGLFCHSKKTRIPGTEDMDKEYRNPWHHIKGAGIGTIIGAVVALLSGGMVHFISII
>NZ_CP013850.1|WP_024933466.1|2015385_2016000_+|sugar-O-acetyltransferase
MNQKDRMLAGLPYKACLDGLPEERMANKKKIYEYNHCFPDEHEKIHKLIRDILGKAGADVHIESPFYCDYGKNIQVGDNFFANYNCTILDVGKVIIGNNVQFAPNVSLYTAGHPIHPDSRNSGYEYGIGITIGDNVWLGGNVVVNPGVHIGNNVVIGSGSVVTKDIPDNVIAIGNPCKVIREITEEDRKYYYKNYEFDVDDYKE
>NZ_CP013850.1|WP_024933467.1|2014708_2015062_-|aminopeptidase-P-family-N-terminal-domain-containing-protein
MHLFINKNKLSDEIKSSLKKNAALFIHPYNKIYKEVKKFTNSDVVLVHPDRINYELYNNIDKEVITEISSSNKLDAFPAEQGRFICPSFEPISSFGEHVTIVTCIFLMENSFMVVTV
>NZ_CP013850.1|WP_024933145.1|2025805_2026294_-|hypothetical-protein
MISKKIIAFIAMTIMMISLLIGCSNNTMDKVYNDNIKIASVYDTFGLDKSDEIIESGIYKGKLKLSGSGTIWTYESSSDFDLKVPYILSVKSGKAKIVLISPDNTVVNLVENTDKATMKGTTSLTLPIKKGNNRIKLVGYKKADIDIELHIEKGTFEKISFN
>NZ_CP013850.1|WP_024933146.1|2027121_2027715_+|glycerol-3-phosphate-acyltransferase
MIIIITSIISFLLGSIPTGYFITKKTCGIDIRTKGSGNIGSTNVKRIVGTKISIITQTIDVLKGIIPVVLGISLSKIVKLPVSIDTYLSIIAIAAILGHDYTPFLKFKGGKGVNTTLGVFIFIAPIPTLTGLAVYFILGLFIRIVSIRSISIGITIPIMCIITKLPIQIIISTTIACILMIIRHKDNLVRLIRGEEK
>NZ_CP013850.1|WP_024933147.1|2028054_2028801_+|cell-envelope-integrity-protein-TolA
MDKFRNMKKSHIALLVIMYMVLMGSLPRFTGWATIFSAIAVGGYFLKNKKDLKELTRKKKNFIFAGIIILAIIGSFNVAVGNNIQNEKLLAEKSKQEQQIKKEQEEKKLAEEQKRIQEEEARKKAEEEKRKQEEEAKKKTEEEAKKKALEEQKKQEELKRKQEEENKVKAENEQAQAAFAQSTGKGDSNSQSNESQNADDNQNYTVYKTRTGSKYHSSGCRYLKKSCYETTVSQARNEGLTPCRVCNP
>NZ_CP013850.1|WP_024933148.1|2029138_2029540_+|membrane-protein
MNILISTCNIGIPVLMIFIGILYKCNLYKKIDKTLDLIVPIAMFFTGFSERDREHLYKNTNKLALVNRKCSLIWSISGVCTLLLTIISLILNKSDIYNTSVILLEPEFLILVIVFITVEYVLKRNFYKKIQQS
>NZ_CP013850.1|WP_011986655.1|2029775_2030492_+|transaldolase
MKYNDLKIKIFADGADLNGMLDAYNKGIVKGFTTNPSLMKKAGITDYKEFAKEVLAKIKDMPVSFEVFSDDLETMEKEAEVLGNLGENVYIKIPVTNTKGESTAPLIKKLSEKGYHLNVTAIFTIDQVKEVVGALKSGVDSIVSVFAGRIADTGEDPVKIMKEASKICKTKEGVELLWASCREFYSIVEADKCGCEIITVTNDVLKKMPNMGKDLKEYSIETVRGFYKDASSLGFSIL
>NZ_CP013850.1|WP_011986654.1|2030515_2030953_+|PTS-sugar-transporter-subunit-IIA
MLKNYINDQVVEVNVEVKNWEEAVRLGGKLLEEDGAVEHSYIDAMVDTVKNMGPYIVIAPGIAMPHARPEAGAKNIRIGLLKLKNPVNFGNEEHDPVDMVIFLCAVDNKAHIEVLGELVQLIEDDDFLKIVRNASTKKEILDYIK
>NZ_CP013850.1|WP_003361919.1|2030981_2031266_+|PTS-sugar-transporter-subunit-IIB
MNILTVCGNGIGSSLMLAMKIEEICKENGIAANVESTDFNSAQGKKADLIVTVKELAEQFEGRDVAVVRSYINKKKITEDVLEIIKQKDEELKK
>NZ_CP013850.1|WP_003358211.1|2031278_2032643_+|PTS-ascorbate-transporter-subunit-IIC
MLGLLQFLRDVLKQPALLMGIMALVGLVALKKPGHKVLTGTLKPILGYLMLGAGADFIVANLEPLGGMIQTGFNITGVVPNNEAIVAVAQKVLGVETMSILVVGLLINLVIARFTKYKYVFLTGHHSFFMACLLSAVLGTSGMKGTELILFGGFLLGAWSAISPAIGQKYTLKVTDGDEIAMGHFGSLAYYVSAWVGSKVGKPEESTENIEIPEKWGFLRDTTISTAITMMVFYIVAAVAAGPEYVSKLSDGMSPILFAIMSSLKFAVGVTIVYNGVRMILGDLIPAFQGIATKIIPDAIPAVDCAVFFPYAPTAVIIGFVSSFIGGIIGMVLLGVAGGVLIIPGLVPHFFCGSTAGIFGNATGGKKGAVIGSFVNGLLITFAPALLLPVLSTLGFKNTTFGDFDFGVLGIIIGKTSNLAGKTGIIIIAMLMLVALIVPNFIKTKSKALNNIEE
>NZ_CP013850.1|WP_024933149.1|2032854_2034948_+|transcription-antiterminator
MLNKRCSNILQMIVNNEKPITIKEISKKVNKSPRTVRYDLDKIDDYLTEIEFPKLERKSNLGISLDLKDEEIKKLFKIIGKINNYDYVLSQKERVFYIIYELLNKSEFATINMLSDRMMVSRSTIINDLIEVKKWLSENKITLESSKGQGIKILGRERDLRRAAVKLFFQSMDSINFFNVTTLKLFNDIDIDFIRNTIKIAEEQMETSFSDDAFNNLVIHIAIAIKRIELSKDIIMDSEELKNLRKTAEYVIASGIAKMLEDRFKISIPEDEIGYITIHILGSNTSTLENIVKDDWIYLHLIVFKLIENVENITGINFSKDNKLFDSLAQHIRPAIYRLKHDIKVKNPLIEEIKEKYSYIFESIEEGVKFIEEDIGDSVNQEEIGYLTLHFMASIERSKNKKHRKPNVLIVCATGIGTSKFISNKLKSIFDINIIDTISSHTMEKILKYNKNIDLIVTTIPLKVKGIKCIEVNTFLTEKNISELGLYFAKFIRNNSEECNGSCKYEERDKVQEILNIVKENCTIHDYYKLRNKLALYLNIKDPTLTEDHKPSLKELLKPDFIKLNEEAENWEDAVRKSGEILMNNGCVKESYIDAMVNTVKNMGPYIVIAPGIAMPHAAPEDGVLKTGISMLTLKDPISFGNSEHDPVSVIISICSIDKVNHMKALKELMSIMDQEDFISKVKNIKASSEIDSILYS
>NZ_CP013850.1|WP_021134329.1|2035273_2035627_+|zinc-ribbon-domain-containing-protein
MIIWGWGKVTKKIIGAVFERTCNYCNTDEVWNLCVVRTWFTLFFIPIIPYKKQYCIACPKCWSYIELTQEEFEKIKIDITSSSNNINEKVVTDNIKYAGKTETQINYLKQMEEYSNK

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Crispr_ID: NZ_CP013850_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP013850_5

2025315-2025673

TypeIII

III-B

Consensus_repeat	Method
ATTGAACATTAACATGAGATGTATTTAAATT	PILER-CR
ATTGAACATTAACATGAGATGTATTTAAAT	CRISPRCasFinder
ATTGAACANTAACATGNGATGTATTTAAAT	CRT

5 spacers

csx1,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10

The CRISPR arrays of NZ_CP013850_5

>merge|NZ_CP013850|5|2025315-2025673|PILER-CR,CRISPRCasFinder,CRT
ATTGAACATTAACATGAGATGTATTTAAATTGATGAAAAATAATTATGCACCTGGATATTTAAGAAATTGAACATTAACATGAGATGTATTTAAATAAATTTATGGATCTAATACTCATAAAGATGATTTTATTGAACATTAACATGAGATGTATTTAAATTTTATTAGTGCCATTCCCGCTGGAGAGTATTGTGTCCATTGAACATTAACATGAGATGTATTTAAATAATGTTAAAACAGTTACACCAGCTACAAGACCAAAGGTTGAATAGTAACATGGGATGTATTTAAATTGGCTTCTTATTGCCTGTTGTATCTTTTCTGGTAGATTGAGCACTAAGATAGGATGTATTTAAAC

>NZ_CP013850|5|2|2025315-2025476|PILER-CR
ATTGAACATTAACATGAGATGTATTTAAATT	GATGAAAAATAATTATGCACCTGGATATTTAAGAA
ATTGAACATTAACATGAGATGTATTTAAATA	AATTTATGGATCTAATACTCATAAAGATGATTTT
ATTGAACATTAACATGAGATGTATTTAAATT

>NZ_CP013850|5|5|2025315-2025673|CRISPRCasFinder
ATTGAACATTAACATGAGATGTATTTAAAT	TGATGAAAAATAATTATGCACCTGGATATTTAAGAA
ATTGAACATTAACATGAGATGTATTTAAAT	AAATTTATGGATCTAATACTCATAAAGATGATTTT
ATTGAACATTAACATGAGATGTATTTAAAT	TTTATTAGTGCCATTCCCGCTGGAGAGTATTGTGTCC
ATTGAACATTAACATGAGATGTATTTAAAT	AATGTTAAAACAGTTACACCAGCTACAAGACCAAAG
GTTGAATAGTAACATGGGATGTATTTAAAT	TGGCTTCTTATTGCCTGTTGTATCTTTTCTGGTAG
ATTGAGCACTAAGATAGGATGTATTTAAAC

>NZ_CP013850|5|1|2025315-2025673|CRT
ATTGAACATTAACATGAGATGTATTTAAAT	TGATGAAAAATAATTATGCACCTGGATATTTAAGAA
ATTGAACATTAACATGAGATGTATTTAAAT	AAATTTATGGATCTAATACTCATAAAGATGATTTT
ATTGAACATTAACATGAGATGTATTTAAAT	TTTATTAGTGCCATTCCCGCTGGAGAGTATTGTGTCC
ATTGAACATTAACATGAGATGTATTTAAAT	AATGTTAAAACAGTTACACCAGCTACAAGACCAAAG
GTTGAATAGTAACATGGGATGTATTTAAAT	TGGCTTCTTATTGCCTGTTGTATCTTTTCTGGTAG
ATTGAGCACTAAGATAGGATGTATTTAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP013850.1\|WP_024933148.1\|2029138_2029540_+\|membrane-protein	unknown	unknown	unknown
NZ_CP013850.1\|WP_075143157.1\|2020199_2021255_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	cd09663_csm4gr5_CAS-III-A	gnl\|CDD\|380071
NZ_CP013850.1\|WP_075143155.1\|2022338_2023820_+\|hypothetical-protein	csx1	mkCas0109_csx1_CAS-III	gnl\|CDD\|187878
NZ_CP013850.1\|WP_003358211.1\|2031278_2032643_+\|PTS-ascorbate-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|236502
NZ_CP013850.1\|WP_075143154.1\|2023836_2024526_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273848
NZ_CP013850.1\|WP_024933464.1\|2016868_2019019_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
NZ_CP013850.1\|WP_024933145.1\|2025805_2026294_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227595
NZ_CP013850.1\|WP_024933147.1\|2028054_2028801_+\|cell-envelope-integrity-protein-TolA	unknown	unknown	gnl\|CDD\|236545
NZ_CP013850.1\|WP_024933149.1\|2032854_2034948_+\|transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP013850.1\|WP_024933467.1\|2014708_2015062_-\|aminopeptidase-P-family-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|379790
NZ_CP013850.1\|WP_024933465.1\|2016042_2016537_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013850.1\|WP_024933466.1\|2015385_2016000_+\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
NZ_CP013850.1\|WP_011986654.1\|2030515_2030953_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|238129
NZ_CP013850.1\|WP_024933146.1\|2027121_2027715_+\|glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl\|CDD\|172889
NZ_CP013850.1\|WP_024933462.1\|2019448_2020198_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NZ_CP013850.1\|WP_011986655.1\|2029775_2030492_+\|transaldolase	unknown	unknown	gnl\|CDD\|183481
NZ_CP013850.1\|WP_021134329.1\|2035273_2035627_+\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|379915
NZ_CP013850.1\|WP_003361919.1\|2030981_2031266_+\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99905
NZ_CP013850.1\|WP_075143156.1\|2021244_2022336_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|273863
NZ_CP013850.1\|WP_024933463.1\|2019037_2019436_+\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl\|CDD\|367635

Protein	Function_ID	Function_description	E-value
NZ_CP013850.1\|WP_075143157.1\|2020199_2021255_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl\|CDD\|380071	pfam17953, Csm4_C, CRISPR Csm4 C-terminal domain. Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci play a pivotal role in the prokaryotic host defense system against invading genetic materials. The CRISPR loci are transcribed to produce CRISPR RNAs (crRNAs), which form interference complexes with CRISPR-associated (Cas) proteins to target the invading nucleic acid for degradation. The interference complex of the type III-A CRISPR-Cas system is composed of five Cas proteins (Csm1-Csm5) and a crRNA, and targets invading DNA. This entry represents the C-terminal domain found in Csm4. Csm4 structurally resembles Cmr3, a component of the type III-B CRISPR-Cas interference complex. Studies indicate that Csm3-Csm4 complex binds single-stranded RNA in a non-sequence-specific manner. Structural analysis show, Csm3 and Csm4 have one and two ferredoxin-like folds (also known as an RRM-like fold), respectively. The long beta-hairpin inserted into the C-terminal ferredoxin-like fold of Csm4, is well-conserved in the Cmr3 structure. The corresponding beta-hairpin of Cmr3 binds the D1 domain of Cmr2, as observed in the Cmr2-Cmr3 complex structure. Furthermore, it is suggested that the hairpin of Csm4 is responsible for the interaction with Csm1 (ortholog of Cmr2).	3.43304e-17
NZ_CP013850.1\|WP_075143155.1\|2022338_2023820_+\|hypothetical-protein	gnl\|CDD\|187878	cd09747, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as Cas02710 family.	3.51889e-09
NZ_CP013850.1\|WP_024933147.1\|2028054_2028801_+\|cell-envelope-integrity-protein-TolA	gnl\|CDD\|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	1.38627e-11
NZ_CP013850.1\|WP_024933146.1\|2027121_2027715_+\|glycerol-3-phosphate-acyltransferase	gnl\|CDD\|172889	PRK14413, PRK14413, glycerol-3-phosphate acyltransferase.	4.80542e-92
NZ_CP013850.1\|WP_003358211.1\|2031278_2032643_+\|PTS-ascorbate-transporter-subunit-IIC	gnl\|CDD\|236502	PRK09410, ulaA, PTS system ascorbate-specific transporter subunit IIC; Reviewed.	0
NZ_CP013850.1\|WP_024933464.1\|2016868_2019019_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	4.54862e-98
NZ_CP013850.1\|WP_024933145.1\|2025805_2026294_-\|hypothetical-protein	gnl\|CDD\|227595	COG5270, COG5270, PUA domain (predicted RNA-binding domain) [Translation, ribosomal structure and biogenesis].	0.00379916
NZ_CP013850.1\|WP_075143154.1\|2023836_2024526_+\|hypothetical-protein	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	0.00384193
NZ_CP013850.1\|WP_024933149.1\|2032854_2034948_+\|transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	5.72803e-58
NZ_CP013850.1\|WP_024933467.1\|2014708_2015062_-\|aminopeptidase-P-family-N-terminal-domain-containing-protein	gnl\|CDD\|379790	pfam16189, Creatinase_N_2, Creatinase/Prolidase N-terminal domain.	2.05273e-11
NZ_CP013850.1\|WP_024933466.1\|2015385_2016000_+\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	2.33547e-98
NZ_CP013850.1\|WP_011986654.1\|2030515_2030953_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	9.05568e-38
NZ_CP013850.1\|WP_024933462.1\|2019448_2020198_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	3.68348e-77
NZ_CP013850.1\|WP_011986655.1\|2029775_2030492_+\|transaldolase	gnl\|CDD\|183481	PRK12376, PRK12376, putative translaldolase; Provisional.	3.52947e-157
NZ_CP013850.1\|WP_021134329.1\|2035273_2035627_+\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|379915	pfam17032, zinc_ribbon_15, zinc-ribbon family. This zinc-ribbon region is found on a set of largely microsporidia-specific proteins.	0.000183435
NZ_CP013850.1\|WP_003361919.1\|2030981_2031266_+\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|99905	cd05563, PTS_IIB_ascorbate, PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a transmembrane channel IIC subunit. Subunits IIA, IIB, and IIC are encoded by the sgaA, sgaB, and sgaT genes of the E. coli sgaTBA operon. In some bacteria, the IIB (SgaB) domain is fused C-terminal to the IIA (SgaT) domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include ascorbate, chitobiose/lichenan, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	2.52704e-28
NZ_CP013850.1\|WP_075143156.1\|2021244_2022336_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|273863	TIGR01899, cas_TM1807_csm5, CRISPR type III-A/MTUBE-associated RAMP protein Csm5. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm5, for CRISPR/cas Subtype Mtube, protein 5.	3.88011e-18
NZ_CP013850.1\|WP_024933463.1\|2019037_2019436_+\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	5.57512e-09

>NZ_CP013850.1|WP_075143154.1|2023836_2024526_+|hypothetical-protein
MHYYQLKIRVKLENNINYIQAPYLIGTFINNCMLKNDMLKNIHKKKIYKYVYDSFFPIEKDGIYKREKYYNIQLRTINLNLINKLAIALYNHKFNGIKTVNIDLEVMEPTKINQLYTLKPSIVTITGQPWIKNKHSIDVLIGNLNANLEKKYKQIFNEELENNKSFIKKIKVVNNIPIKYEYKNIILLGNKFEIIVNEDEVSQRKATIALGMGLGEKGSSLGAGFCIYR
>NZ_CP013850.1|WP_075143155.1|2022338_2023820_+|hypothetical-protein
MDNVLIINLGNSDIEKEGNKIEFGEFREKTKKIYEQLEGANKEEKQEIFKYLDFPIIKAIIDKVDGELKNEKLDKVILAYTNQKFNNNKDTVYLYEILKQKKHLVNNLETDNQDIWEKRLKETNFKQSYNIDFDPSDIDRMYNFYAEEINELNNKKIKKLFFSITGGASAMNFALLINAIEKFSGQLIPCYLSRGKKVAYKVNIAKNLRKQILKRDIKILINNKDYFAAIKMLENLEDGIVDDMSKLELKNIILALKYAEARIQFNFDKCKEYGEKCLDNTAEYREEFSQAVKDILIEKDDYINRLVELKNNAIYLYKKGSYTDFLGRVYRFQEAVYEHILGQYDLIIEKSNGVKINKEILKSRYSDKKEILDNIKIAGNKLEYEKNLTVDAMSKIISTLIDNDDVRNIVNRMEEIKDVKQLRNKSILAHGFEGISKEKIQGKLNCEEKDISKLLEEVMCKILVLFKIGTIEDMFYCENSRYDCILIEMIEKL
>NZ_CP013850.1|WP_075143156.1|2021244_2022336_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MNYDKIILNLKGQVLTPVHIGCGKKYSPYLDIIKNENKITVLDEEKIIEKLVLNDEIFEEYINILKNKSPNAIEKYNIINILKNNKIEIGEVKKYDLICGNSFNNLIDVNQSIKTKGIPYIPGSSIKGSIRTALIYNKLLKNGIDFGKIKEISNLKNKYYCYLGQDIFRQNDKLIYDDMMKNLLVRDTDIISNNKVKVYLCRAVNLYESIKNGNISTSVKSLNECIEEYTDFTFSIIIKNSLISKEELYNNINSFYEKILLKEIQEIEKLKLNIINSQYKLLLNEINEFRKYNNGFILRIGGMKGIFSNTIDSILSKKELEDIRNAHKNKRKKTGEFPTTKWCVMDEYENIKTTLGWIKIMEE
>NZ_CP013850.1|WP_075143157.1|2020199_2021255_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MKKVILKIDNETKFHIGNGQEILEYIPSDKLYSAIINSLALTYSKYELNKLIEIINEKLQISSAFMGIKIKNKNKGIEKSIDFLPRPYMYIGNNNIISTQLLNRKKFKKINYVSNNVFLDFNKHYDSKKNFINYDFQQGYIIGEKYYVTDREINFLSEDEKKYLEKYKPIINESVQRNYINRFSKESIGTYYDNFKVIVQEKYKDMQLIPYFYFYIKGDLEIDKIMYAIIEGGIGGKRSLGAGTIKDISIEECDDFKENGERFINISMIYPDKQELNYIESYALENRNGYIYSQGPTDLKKPWIRMIKEGGVFTKRIKGNINDINVKDIDYPIYTYGKAFFITLGGNLDEL
>NZ_CP013850.1|WP_024933462.1|2019448_2020198_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MNLLMGKIFIDGDIILKTGLRIGGGNNSIEIGGIDNNVIKNHRGEPYIPGSSLKGKLRSLLEISTNRLKDGRPCNCGECSICSIFGVGANENKQNLPTRIIVRDAFLNEDIKKQMYEKQGQFKRLELNYTESKYENTIDRLNSKATPRLIERVPEGASFRLQIIYSVFNNKDIDNFNDLIKGMKLLEDDYLGSNGSRGYGQVEFDNLNIKIKVIKDYKTKEVLNKSSLTDIDSVCLKEKLNELIEIKGV
>NZ_CP013850.1|WP_024933463.1|2019037_2019436_+|type-III-A-CRISPR-associated-protein-Csm2
MEKDYKTDKFREYEEYFKKNVLTLDKINYDQFIEKSKDYSRLLKNNGLTTSMIRKIYNEILKANEAIDLKRLRPILAYTYGRNRVKGLQSLFYTLDDLLKRLNLKTNYLEIENVKEFLEVIIAYMKFYGDRY
>NZ_CP013850.1|WP_024933464.1|2016868_2019019_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MHICYKSLLYSFLRYVESIDKAMYKENAFKLKDKLLNPILQESYELVTKNIKKKKCKDGTFRLMNIFSNINDSKRKKFNLLKEIDINRYDNILKENGEEIDKAYCINYVKSIIKKLLQNDNEKIYFLMSKYCSNVPFINSKNCDISLFDIAKVTAAIATCKEKNKEEYILIKGDFSGIQSFIFKTSSDGALKTLKGRSVYLTLLQEICAKYIVKELGLSLCNILYSGGGNFYILASKSDENKIKLLRKQLSKLILKAYNGEIYLALGYLSFKEEDFKNFNILWKNIGEEVGFLKSKRWSELNLKESFNEIFGPLDLGGRREHSCRLCGCINKNLKEGMCDLCISFKDFSMEMKKANFYCEKIIPKADISLHNNVKDIFHELGFEIKFSDKPLKGFKNYIINSCDFEAYDGFIFKSVKLSDESLDYMVQKQKGNNKVGVIKLDIDNLGKLFINGLGNEGSISKIISLSRNISMFFEGYIENILYKSKRLDKLKEYLKTSDWEKRVTIIFSGGDDTFIIGRYEEILEFALLIREVFEEFVGGEQLTFSAGIGIFDYNYPVINIAEDTERCLELAKNHIEGNEIYAKKNKVCIMGQVFTWNEFLEIIKLKNLIEEIYLLSSKKSIFEKINKSTLGFKAVVEGGKRLNYIKLHRLAYYLRDLNNASNKNLKNKVEELIEFYEELCLKAFMGNNKKNYNINNIMIIPVASKLAQYNYRIIN
>NZ_CP013850.1|WP_024933465.1|2016042_2016537_+|hypothetical-protein
MILAIECFIACVLFTLMILPSLYKEPMKHIMSYPTEIRKRVESLPQYKDAIQKKEKKHLTVKIIAVFMFAIIFAVVAYFSGAKSFSKAYIHVFTLFFVVNIYDMIVLDIGLFCHSKKTRIPGTEDMDKEYRNPWHHIKGAGIGTIIGAVVALLSGGMVHFISII
>NZ_CP013850.1|WP_024933466.1|2015385_2016000_+|sugar-O-acetyltransferase
MNQKDRMLAGLPYKACLDGLPEERMANKKKIYEYNHCFPDEHEKIHKLIRDILGKAGADVHIESPFYCDYGKNIQVGDNFFANYNCTILDVGKVIIGNNVQFAPNVSLYTAGHPIHPDSRNSGYEYGIGITIGDNVWLGGNVVVNPGVHIGNNVVIGSGSVVTKDIPDNVIAIGNPCKVIREITEEDRKYYYKNYEFDVDDYKE
>NZ_CP013850.1|WP_024933467.1|2014708_2015062_-|aminopeptidase-P-family-N-terminal-domain-containing-protein
MHLFINKNKLSDEIKSSLKKNAALFIHPYNKIYKEVKKFTNSDVVLVHPDRINYELYNNIDKEVITEISSSNKLDAFPAEQGRFICPSFEPISSFGEHVTIVTCIFLMENSFMVVTV
>NZ_CP013850.1|WP_024933145.1|2025805_2026294_-|hypothetical-protein
MISKKIIAFIAMTIMMISLLIGCSNNTMDKVYNDNIKIASVYDTFGLDKSDEIIESGIYKGKLKLSGSGTIWTYESSSDFDLKVPYILSVKSGKAKIVLISPDNTVVNLVENTDKATMKGTTSLTLPIKKGNNRIKLVGYKKADIDIELHIEKGTFEKISFN
>NZ_CP013850.1|WP_024933146.1|2027121_2027715_+|glycerol-3-phosphate-acyltransferase
MIIIITSIISFLLGSIPTGYFITKKTCGIDIRTKGSGNIGSTNVKRIVGTKISIITQTIDVLKGIIPVVLGISLSKIVKLPVSIDTYLSIIAIAAILGHDYTPFLKFKGGKGVNTTLGVFIFIAPIPTLTGLAVYFILGLFIRIVSIRSISIGITIPIMCIITKLPIQIIISTTIACILMIIRHKDNLVRLIRGEEK
>NZ_CP013850.1|WP_024933147.1|2028054_2028801_+|cell-envelope-integrity-protein-TolA
MDKFRNMKKSHIALLVIMYMVLMGSLPRFTGWATIFSAIAVGGYFLKNKKDLKELTRKKKNFIFAGIIILAIIGSFNVAVGNNIQNEKLLAEKSKQEQQIKKEQEEKKLAEEQKRIQEEEARKKAEEEKRKQEEEAKKKTEEEAKKKALEEQKKQEELKRKQEEENKVKAENEQAQAAFAQSTGKGDSNSQSNESQNADDNQNYTVYKTRTGSKYHSSGCRYLKKSCYETTVSQARNEGLTPCRVCNP
>NZ_CP013850.1|WP_024933148.1|2029138_2029540_+|membrane-protein
MNILISTCNIGIPVLMIFIGILYKCNLYKKIDKTLDLIVPIAMFFTGFSERDREHLYKNTNKLALVNRKCSLIWSISGVCTLLLTIISLILNKSDIYNTSVILLEPEFLILVIVFITVEYVLKRNFYKKIQQS
>NZ_CP013850.1|WP_011986655.1|2029775_2030492_+|transaldolase
MKYNDLKIKIFADGADLNGMLDAYNKGIVKGFTTNPSLMKKAGITDYKEFAKEVLAKIKDMPVSFEVFSDDLETMEKEAEVLGNLGENVYIKIPVTNTKGESTAPLIKKLSEKGYHLNVTAIFTIDQVKEVVGALKSGVDSIVSVFAGRIADTGEDPVKIMKEASKICKTKEGVELLWASCREFYSIVEADKCGCEIITVTNDVLKKMPNMGKDLKEYSIETVRGFYKDASSLGFSIL
>NZ_CP013850.1|WP_011986654.1|2030515_2030953_+|PTS-sugar-transporter-subunit-IIA
MLKNYINDQVVEVNVEVKNWEEAVRLGGKLLEEDGAVEHSYIDAMVDTVKNMGPYIVIAPGIAMPHARPEAGAKNIRIGLLKLKNPVNFGNEEHDPVDMVIFLCAVDNKAHIEVLGELVQLIEDDDFLKIVRNASTKKEILDYIK
>NZ_CP013850.1|WP_003361919.1|2030981_2031266_+|PTS-sugar-transporter-subunit-IIB
MNILTVCGNGIGSSLMLAMKIEEICKENGIAANVESTDFNSAQGKKADLIVTVKELAEQFEGRDVAVVRSYINKKKITEDVLEIIKQKDEELKK
>NZ_CP013850.1|WP_003358211.1|2031278_2032643_+|PTS-ascorbate-transporter-subunit-IIC
MLGLLQFLRDVLKQPALLMGIMALVGLVALKKPGHKVLTGTLKPILGYLMLGAGADFIVANLEPLGGMIQTGFNITGVVPNNEAIVAVAQKVLGVETMSILVVGLLINLVIARFTKYKYVFLTGHHSFFMACLLSAVLGTSGMKGTELILFGGFLLGAWSAISPAIGQKYTLKVTDGDEIAMGHFGSLAYYVSAWVGSKVGKPEESTENIEIPEKWGFLRDTTISTAITMMVFYIVAAVAAGPEYVSKLSDGMSPILFAIMSSLKFAVGVTIVYNGVRMILGDLIPAFQGIATKIIPDAIPAVDCAVFFPYAPTAVIIGFVSSFIGGIIGMVLLGVAGGVLIIPGLVPHFFCGSTAGIFGNATGGKKGAVIGSFVNGLLITFAPALLLPVLSTLGFKNTTFGDFDFGVLGIIIGKTSNLAGKTGIIIIAMLMLVALIVPNFIKTKSKALNNIEE
>NZ_CP013850.1|WP_024933149.1|2032854_2034948_+|transcription-antiterminator
MLNKRCSNILQMIVNNEKPITIKEISKKVNKSPRTVRYDLDKIDDYLTEIEFPKLERKSNLGISLDLKDEEIKKLFKIIGKINNYDYVLSQKERVFYIIYELLNKSEFATINMLSDRMMVSRSTIINDLIEVKKWLSENKITLESSKGQGIKILGRERDLRRAAVKLFFQSMDSINFFNVTTLKLFNDIDIDFIRNTIKIAEEQMETSFSDDAFNNLVIHIAIAIKRIELSKDIIMDSEELKNLRKTAEYVIASGIAKMLEDRFKISIPEDEIGYITIHILGSNTSTLENIVKDDWIYLHLIVFKLIENVENITGINFSKDNKLFDSLAQHIRPAIYRLKHDIKVKNPLIEEIKEKYSYIFESIEEGVKFIEEDIGDSVNQEEIGYLTLHFMASIERSKNKKHRKPNVLIVCATGIGTSKFISNKLKSIFDINIIDTISSHTMEKILKYNKNIDLIVTTIPLKVKGIKCIEVNTFLTEKNISELGLYFAKFIRNNSEECNGSCKYEERDKVQEILNIVKENCTIHDYYKLRNKLALYLNIKDPTLTEDHKPSLKELLKPDFIKLNEEAENWEDAVRKSGEILMNNGCVKESYIDAMVNTVKNMGPYIVIAPGIAMPHAAPEDGVLKTGISMLTLKDPISFGNSEHDPVSVIISICSIDKVNHMKALKELMSIMDQEDFISKVKNIKASSEIDSILYS
>NZ_CP013850.1|WP_021134329.1|2035273_2035627_+|zinc-ribbon-domain-containing-protein
MIIWGWGKVTKKIIGAVFERTCNYCNTDEVWNLCVVRTWFTLFFIPIIPYKKQYCIACPKCWSYIELTQEEFEKIKIDITSSSNNINEKVVTDNIKYAGKTETQINYLKQMEEYSNK

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Crispr_ID: NZ_CP013850_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP013850_6

2417747-2417964

Unclear

Consensus_repeat	Method
AGATATATCTTCTATATTATTAT	CRISPRCasFinder

3 spacers

cas3

The CRISPR arrays of NZ_CP013850_6

>merge|NZ_CP013850|6|2417747-2417964|CRISPRCasFinder
TTCTATATTTTCTATTTTATTATCTCTTAGATCTAAATGATGTAAGTTTAAATCCTTTAAATAAGATATGTCTTTTACTTTATTTTTAGATAAATTTATATCCTTTAGTTTTTCCATATTATTAATAGGAGATATATCTTCTATATTATTATTATATAAATTTAATAATTCTAAACTATCAAGTCCCTTTAAACAAGATATATCTTTTATATTATTAT

>NZ_CP013850|6|6|2417747-2417964|CRISPRCasFinder
TTCTATATTTTCTATTTTATTAT	CTCTTAGATCTAAATGATGTAAGTTTAAATCCTTTAAATA
AGATATGTCTTTTACTTTATTTT	TAGATAAATTTATATCCTTTAGTTTTTCCATATTATTAATAGG
AGATATATCTTCTATATTATTAT	TATATAAATTTAATAATTCTAAACTATCAAGTCCCTTTAAACA
AGATATATCTTTTATATTATTAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP013850.1\|WP_085320778.1\|2409242_2410601_+\|YjiH-family-protein	unknown	unknown	gnl\|CDD\|225851
NZ_CP013850.1\|WP_085320776.1\|2413122_2414052_-\|glucosaminidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|224619
NZ_CP013850.1\|WP_085320779.1\|2404852_2405326_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013850.1\|WP_012099788.1\|2405619_2406600_-\|tyrosine-recombinase-XerC	unknown	unknown	gnl\|CDD\|234698
NZ_CP013850.1\|WP_085320771.1\|2426326_2427592_-\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|223587
NZ_CP013850.1\|WP_003358886.1\|2408039_2408240_-\|alpha/beta-type-small-acid-soluble-spore-protein	unknown	unknown	gnl\|CDD\|365990
NZ_CP013850.1\|WP_085320770.1\|2432229_2434233_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
NZ_CP013850.1\|WP_075143871.1\|2430386_2431967_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|237894
NZ_CP013850.1\|WP_003403076.1\|2412481_2412997_+\|ferritin	unknown	unknown	gnl\|CDD\|153113
NZ_CP013850.1\|WP_061309457.1\|2435459_2436095_+\|SafA/ExsA-family-spore-coat-assembly-protein	unknown	unknown	gnl\|CDD\|131955
NZ_CP013850.1\|WP_003358868.1\|2410773_2411235_-\|chemotaxis-protein-CheC	unknown	unknown	gnl\|CDD\|224324
NZ_CP013850.1\|WP_085320774.1\|2418928_2423389_-\|DUF5050-domain-containing-protein	unknown	unknown	gnl\|CDD\|379846
NZ_CP013850.1\|WP_085320773.1\|2423542_2424988_-\|DEAD/DEAH-box-helicase	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|223587
NZ_CP013850.1\|WP_003358979.1\|2429066_2429921_-\|4Fe-4S-binding-protein	unknown	unknown	gnl\|CDD\|225131
NZ_CP013850.1\|WP_003358991.1\|2411234_2412089_-\|response-regulator	unknown	unknown	gnl\|CDD\|381097
NZ_CP013850.1\|WP_085320772.1\|2425167_2426004_-\|S1-RNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|225543
NZ_CP013850.1\|WP_003359090.1\|2408301_2408505_-\|alpha/beta-type-small-acid-soluble-spore-protein	unknown	unknown	gnl\|CDD\|365990
NZ_CP013850.1\|WP_078983311.1\|2407518_2407848_+\|HesB-like-protein	unknown	unknown	gnl\|CDD\|188182
NZ_CP013850.1\|WP_061309456.1\|2436238_2437198_-\|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	unknown	unknown	gnl\|CDD\|238916
NZ_CP013850.1\|WP_003359089.1\|2427964_2428858_+\|chemotaxis-protein-CheV	unknown	unknown	gnl\|CDD\|223905

Protein	Function_ID	Function_description	E-value
NZ_CP013850.1\|WP_085320778.1\|2409242_2410601_+\|YjiH-family-protein	gnl\|CDD\|225851	COG3314, COG3314, Uncharacterized protein conserved in bacteria [Function unknown].	3.15674e-116
NZ_CP013850.1\|WP_085320776.1\|2413122_2414052_-\|glucosaminidase-domain-containing-protein	gnl\|CDD\|224619	COG1705, FlgJ, Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion].	8.76147e-48
NZ_CP013850.1\|WP_012099788.1\|2405619_2406600_-\|tyrosine-recombinase-XerC	gnl\|CDD\|234698	PRK00236, xerC, site-specific tyrosine recombinase XerC; Reviewed.	1.61536e-139
NZ_CP013850.1\|WP_085320771.1\|2426326_2427592_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	2.22656e-113
NZ_CP013850.1\|WP_003358886.1\|2408039_2408240_-\|alpha/beta-type-small-acid-soluble-spore-protein	gnl\|CDD\|365990	pfam00269, SASP, Small, acid-soluble spore proteins, alpha/beta type.	1.28764e-24
NZ_CP013850.1\|WP_085320770.1\|2432229_2434233_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	3.94727e-53
NZ_CP013850.1\|WP_075143871.1\|2430386_2431967_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|237894	PRK15064, PRK15064, ABC transporter ATP-binding protein; Provisional.	0
NZ_CP013850.1\|WP_003403076.1\|2412481_2412997_+\|ferritin	gnl\|CDD\|153113	cd01055, Nonheme_Ferritin, nonheme-containing ferritins. Nonheme Ferritin domain, found in archaea and bacteria, is a member of a broad superfamily of ferritin-like diiron-carboxylate proteins. The ferritin protein shell is composed of 24 protein subunits arranged in 432 symmetry. Each protein subunit, a four-helix bundle with a fifth short terminal helix, contains a dinuclear ferroxidase center (H type). Unique to this group of proteins is a third metal site in the ferroxidase center. Iron storage involves the uptake of iron (II) at the protein shell, its oxidation by molecular oxygen at the ferroxidase centers, and the movement of iron (III) into the cavity for deposition as ferrihydrite.	1.58716e-79
NZ_CP013850.1\|WP_061309457.1\|2435459_2436095_+\|SafA/ExsA-family-spore-coat-assembly-protein	gnl\|CDD\|131955	TIGR02909, conserved_hypothetical_protein, uncharacterized protein, YkwD family. Members of this protein family represent a subset of those belonging to pfam00188 (SCP-like extracellular protein). Based on currently cuttoffs for this model, all member proteins are found in Bacteria capable of endospore formation. Members include a named but uncharacterized protein, YkwD of Bacillus subtilis. Only the C-terminal region is well-conserved and is included in the seed alignment for this model. Three members of this family have an N-terminal domain homologous to the spore coat assembly protein SafA.	6.64773e-55
NZ_CP013850.1\|WP_003358868.1\|2410773_2411235_-\|chemotaxis-protein-CheC	gnl\|CDD\|224324	COG1406, COG1406, Predicted inhibitor of MCP methylation, homolog of CheC [Cell motility and secretion].	5.96856e-41
NZ_CP013850.1\|WP_085320774.1\|2418928_2423389_-\|DUF5050-domain-containing-protein	gnl\|CDD\|379846	pfam16472, DUF5050, Domain of unknown function (DUF5050).	1.52705e-50
NZ_CP013850.1\|WP_085320773.1\|2423542_2424988_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	1.76184e-152
NZ_CP013850.1\|WP_003358979.1\|2429066_2429921_-\|4Fe-4S-binding-protein	gnl\|CDD\|225131	COG2221, DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Energy production and conversion].	1.33915e-71
NZ_CP013850.1\|WP_003358991.1\|2411234_2412089_-\|response-regulator	gnl\|CDD\|381097	cd17542, REC_CheY, phosphoacceptor receiver (REC) domain of chemotaxis protein CheY. The chemotaxis response regulator CheY contains a stand-alone REC domain. Chemotaxis is a behavior known for motile bacteria that directs their movement in response to chemical gradients. CheY is involved in transmitting sensory signals from chemoreceptors to the flagellar motors. Phosphorylated CheY interacts with the flagella switch components FliM and FliY, which causes counterclockwise rotation of the flagella, resulting in smooth swimming. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	2.81261e-50
NZ_CP013850.1\|WP_085320772.1\|2425167_2426004_-\|S1-RNA-binding-domain-containing-protein	gnl\|CDD\|225543	COG2996, COG2996, Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only].	9.55462e-82
NZ_CP013850.1\|WP_003359090.1\|2408301_2408505_-\|alpha/beta-type-small-acid-soluble-spore-protein	gnl\|CDD\|365990	pfam00269, SASP, Small, acid-soluble spore proteins, alpha/beta type.	9.622e-26
NZ_CP013850.1\|WP_078983311.1\|2407518_2407848_+\|HesB-like-protein	gnl\|CDD\|188182	TIGR01911, conserved_protein, HesB-like selenoprotein. This model represents a family of small proteins related to HesB and its close homologs, which are likely to be invovlved in iron-sulfur cluster assembly (See TIGR00049 and pfam01521). Several members are selenoproteins, with a TGA codon and Sec residue that aligns to the conserved Cys of the HesB domain. A variable Cys/Ser/Gly-rich C-terminal region is not included in the seed alignment and model. [Unknown function, General].	2.50611e-23
NZ_CP013850.1\|WP_061309456.1\|2436238_2437198_-\|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	gnl\|CDD\|238916	cd01941, YeiC_kinase_like, YeiC-like sugar kinase. Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time.	3.33444e-88
NZ_CP013850.1\|WP_003359089.1\|2427964_2428858_+\|chemotaxis-protein-CheV	gnl\|CDD\|223905	COG0835, CheW, Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms].	2.86594e-31

>NZ_CP013850.1|WP_085320776.1|2413122_2414052_-|glucosaminidase-domain-containing-protein
MKKATGLILKLMILVLLAFTIFIIFNSLILNKTKERFLPESAMNIYIKAADEVSENKLQVNWKYIAALDGVKNKEDFSKANIEDSKVLGKKFLEISKSTKFKNTNYRLLTLDEVISKMSFTEEEKKNVHKYLDKLNNIYPITPDEYKRQFIDELIPISKELYDEYGILPSVTIGQAILESDWGRSELSKKGNNLFGIKATPSWQGKALNMETSENYNDKIKDNFRYYSSKGDSIKDYANFLVKNKRYRENKVFRATEYKTQAKAIEKAGYSTKKDKDGNLLYSSLLGKIIREYNLQLIDSKTQEEISKK
>NZ_CP013850.1|WP_003403076.1|2412481_2412997_+|ferritin
MLSEKLLEALNNQINFEFYSSYIYLAMASYAESEDLAGFANFFRVQAQEEIFHAMKFYDYVNQMGGRVILEKIDQPKAEYKNILECFEDGFNHEKIVTSRIYNLTDIATEEKEHATISLLKWFIDEQVEEENNFNTIIRKLRRAESNPAVLYMLDDELSARVFTPPTNTGA
>NZ_CP013850.1|WP_003358991.1|2411234_2412089_-|response-regulator
MKNTKVVIVDDSPFSISIIKDILEENELTVVGEAGNLEEVINVVKDKKPDIVTMDMTLPGTDGIECIKAINKINKNVKVIVISSMMDEEIVKKANKNKVCGYIQKPIDPEELIATIEKVVMKEELFLQLENDYFQIFKESFKDALNKFTKTTAEFSEDTKCTISETSRGMVVVIGIIGNFSGRMILDLSQETANSMVNFMLKREPKDMNEVLNVIGEFSNIVAGNACSMLNRKNKVFGLRIAPPSIFYGKSLNISQSLIESLSVESNTEFGQIYMNVGFKRGES
>NZ_CP013850.1|WP_003358868.1|2410773_2411235_-|chemotaxis-protein-CheC
MDAKYINPFIDSFYNVLPQIGFSNVTREDVAIKNNVESLGILINLGIVGDIRGNIVYNIQGENGKKIASKMMMGLPVEELNEMAQSALSELSNMLTANASINFSNIGVNVNISTPTLMYGQDIKIKLNTDKILNIKIVADNIPIDVNIAFEKI
>NZ_CP013850.1|WP_085320778.1|2409242_2410601_+|YjiH-family-protein
METQKNNKYSFSELFKFICPSLIGFILFIIPISYDGEITIPIAVLSKIVLAGLGSILPQLMAIIICITFICTAITKIFRPKAILENKFFNNLFNVSPVWVLARILGFIFIVSTFFKIGPEWMWSENTGGLLLYDLLPILFSVFIFAGMLLPLLLDFGLLEFVGALLTKVMRPIFNLPGRSSIDCMASWLGDGTIGVLLTSKQYEEGYYSEREAAVIGTTFSAVSITFSLVVISQVKLAHMFVPFYLTVCLAGIIAAILIPRIPPLSRKPDAYLNGGESKSSEALPEGYTPFTWGLEKAVAKAGSNDDPFNFIKQGLQNVLDMLLGVTPVVMAMGTSALILAEYTPLFKWLGLPFIPLLNLLKIPEAALASQTIVVGFADMFLPSVIAATIQSEMTRFIIACLSVTQLIYMSEVGGLLLGSKIPVSLKDLVIIFLERTLVTLPIITLIAHILF
>NZ_CP013850.1|WP_003359090.1|2408301_2408505_-|alpha/beta-type-small-acid-soluble-spore-protein
MPSNRNSNNLVVPEAQQGLNQLKMEVANEVGIANYDSMDKGNLTSRQNGYVGGNMVKKMVEAYERNL
>NZ_CP013850.1|WP_003358886.1|2408039_2408240_-|alpha/beta-type-small-acid-soluble-spore-protein
MANRNSNNLVVPEAQHGLNQLKMEVANEVGIANYDAVDKGNLTSRQNGYVGGNMVRKMVEAYERNL
>NZ_CP013850.1|WP_078983311.1|2407518_2407848_+|HesB-like-protein
MTPVNMSDLAYKEFKNFIKENNVNSNIFRIFLAGNGUGGPVFNIVLDEQTSEDLLSPIGELSFLVHKDLFSEFGGFIIKCAEENGKGGFTIDPIIHSENISCSTCSSCN
>NZ_CP013850.1|WP_012099788.1|2405619_2406600_-|tyrosine-recombinase-XerC
MKYNIQQLYDANFPQRLNDFLNYLRTIKGKSENTIESYKLDLIMFFRFLKLYKGMVPGETEFNDIEIKDISDEDIKNISLTDLFAFVSFVENYRNNGSYAKARKVATLKSFFRFLQGKVKIIKENPALELESPKISKRNPVYLTLDESKRLLSSIDGKFKERDLCIVTMFLNCGLRLSELCGINISNIKNDILTVVGKGNKERTVYLNKACIKTLNDYLSVRKEMGEKIVDKDALFLSKNYTRINKRSVEMLVKKYVKKAGLDGEKYSPHKLRHTAATLMYKHGGVDIRSLQMILGHENISTTQIYTHVDSDRLREAVKSNPLSDE
>NZ_CP013850.1|WP_085320779.1|2404852_2405326_+|hypothetical-protein
MNRETCIFNYTKKCTDCGECEICDLDQNKKCDNCGECLQREGIDTQAIKIDEIKEDKNFVDKEDLKKVLKEDEKELESLKEFEEGLENEILQETELIKDYDENFKEQGLYAIENVEGVQIEYIEDVDGLSELMEDESRLKKVAYEEFPGLIKIRENK
>NZ_CP013850.1|WP_085320774.1|2418928_2423389_-|DUF5050-domain-containing-protein
MIRGVFAIFSKKFVAKLLLYSSIAIIPMFNHNYVQAASSKQYETKYNVSLDKVWKIRFSREVDKSTLNPENIKILDNQGKEMPIDLSLDVDKHYVKIALKSGTYNGVHYIGKYEKDKKYSLIVKEGLMSEPYKNKKSKNLAYETMMEFNTIGDNEYPGLPIEDGLIVIGDKAYSVEYLSKHSSIANEITSNGNYYIAYISKEYGEKIKQVLGNNTTKGNQERANKILYYAPNGNQYEYEWNEAFGEYKIVLPKAYVDVTPGVINGVVNLAVKQVKAVPGAKYFKLAHSNTIKPIGESISYSMTYPTEKLTILSADETPLATALVDVYLPKTGYVSLSSVNETLGNTAGNISNNGSAAMDLDFYVYYVNSADKNSLYRKTLTGRMDTQISLDKAQYINVIGDWIYYSNYNDNGKIYKMKKDGTKKQILCDDTATYITVSGGVVYYANQSDKGRLYKINTDGTIDGGASNRDPAGKVHGMPVMDDYGNYNKATDQANFINVVGDWIYYSNFSDGHKIYTVNKDGNIRRKVNDEWADGIQIVGAWAYYCSGSGAISKVRVDGTGSVILLRGTTRKVDKGYHLNIVDGWLYYSNAEDGGKLYRIKEDGSGEKKKLADLATDYINIVGDTMYLISAGKTYTLPLNTDGTIKPTLVTKDNNGNTVVDVKDLAITVAYEDANKTIGELETKYLPQKVAVFMKDDTVQQLPVDWDIKNRKYNGQGIYTYTGTVLGHGKQIKCTLTIPSEMLNATSIIEVYNNGPKNGSIMIKERSFGPSKQDQELKEKLKLAKRVEIGDVIKVYDNPNSEKPLGNVKVDANNANGPLVKSLDLDMYGRSFWITITRKNKAESKPTEVRQLGAAVLSGDVLDEDGEALGVDGRDFTVKGWNNPSIRDDGFISDTTEIAAQGTKSIYVIPGTGKLNMENQGVIPAGITSANYWNGGNARALLTNYDLLTNDSLKNKLKEGNYSIYVVVGYDGKAEEDVNGFGSPLVIGKTASIPKAMKATEEKIPKAPSVTKQYVKAGDTIKISGVTNEDEIYLAPEGASYIAKDITNKPYKSHDNLFFEDQSKSKEEREKEYEKSGKPSIEDGYQCKLVDGKIPQGVRSGKYKVYMVNAIGSSSPASGEIVIDNEDPVVRLDSAKQEDVIKTVTNPDGTTRPETTGQKFKVNFAAFDNSFDNSIKEGITVSIARLDSPKSAIKAQEIKDKGNKTFEVIINDPNANLNDYAIYAQDKAGNIGQINLQDKNLPANINNISLAIRTSNEGVDLVKSRLVGRTKYMTKDLTRVSDNYEVTVDGVKYVLQEEALRNLGASPSIDAFMNALMQAKQWDIANNKPMEDKPKLSSKVSIYKVNDIIYIEGNDNTPIQIEDKTKIDADTAIVSNMIGLNSNENSTGENSKNQQYIINVTGTAQKNGKLKVCLAGKCFDIDILSTDDTTKIARKIKDAINDNTILDNYQYPGTNVESNGSKVTLTRKSPGAVVPTFTVEYFNYDN
>NZ_CP013850.1|WP_085320773.1|2423542_2424988_-|DEAD/DEAH-box-helicase
MNKLGFENYELSDEILKSLGRLGYKNPSEVQKQVIPLILKDKDIIVKSETGSGKTAAFSIPICEKIELEEKDPQVLVLTPTRELALQIKEEISSIALYKRLRCTAIFGKQPMSLQKRELKQRVHLVVGTPGRTLDHIERENLDLKKIKYFVLDEADEMLNMGFIDQVEAVIKRLPKNRVTMLFSATIPEKIENLCKKYMNNPKNININPENITTGTINQCYYEVEDKDKFSLLQKIIYKELVDNSIIFCNTREKVDEVLKHMKKKGFNAIALHGGMEQKDRLETMKKFKQGEFQFLVCTDVAARGIHIENISHVINYEMPYEKESYVHRIGRTGRAGKEGVAITFIEPNKVRFLKDIEDYIEKEIPKRKEPSLEEVDKGKKVFEENIKNRIKTKVPKNNKKQKDITKIYISAGRKKKIRPGDIVGAITSIEGINVDNIGIIDIQDNHSYVDILEGKGDIVLKASEDMKIKGKKVRIQRAVK
>NZ_CP013850.1|WP_085320772.1|2425167_2426004_-|S1-RNA-binding-domain-containing-protein
MIKLGEIQKLEIIREAPMGVYLNSKEDKSENDILLPGKQVPKDAKIGDEVEVFVYRDSEDRMIATINRPKITIGEIAPLKVIEKTKMGAFLDCGLERDLFLPFKEQTYGIQEGKECLVYLYIDKSDRLCASMNVYRVLSTESPYKENDEVKGFIYDIKREIGAFVAVDDEYHGLIPKNELYEKFRYGDIVEARVTKVKEDGKLDLSIRKKAYKQMDEDADTILEKLNSNGGKLYLNDNSDPVAIKELLSMSKNAFKRAVGRLLKEGKIEFIENGIKLK
>NZ_CP013850.1|WP_085320771.1|2426326_2427592_-|DEAD/DEAH-box-helicase
MNNSFDTLNLNPKLVQGLKKLNINIPTEIQAKAIPLAMENKDIIGQSETGTGKTLAYLLPIFEKITTEKREMQAIILAPTHELAMQINNEIKNISSNSNMDVKSMAIIGEANIKRQIEKLKEKPHIIVGSPGRILELIKKKKITAHTVKTIVIDEGDKLLDKNNLKVVKEVIKTTLRERQLMLFSATITESTLNIAKDLMKDSEVVKVKEKNTVNENIKHLYITGEHRERIEILRKLIAATNPKRAIVFINRNEEIELTTLKLQYHKIKAYGIYGAAEKEQRKKALEDFRSGKVQILVSSDLSARGLDVKDVTHIFNLDLPENPKEYLHRVGRTGRASKEGIAISIITEKEKALIRKYEKEFNINIEEKKIYKGTLISSKGERSSQPKSKNKSTSAHRDNNKKKRSSSINKSKNNHKKKKY
>NZ_CP013850.1|WP_003359089.1|2427964_2428858_+|chemotaxis-protein-CheV
METNILLESGTGEVEIIEFLVNNKHYAINVIKVKEVIEVDNVTKVPQSDPAIEGLILCREKIFPLIDLSYILGQKNTSKGKFKTIICEFNRVSVAFKIDEIVAVHRIGWDKILKPDDIAANPLVIGNILLKDKIILLLDFEKIVTDINPSTGISEERIVNVDYKDRSHIKVFLADDSSLIRKLLKDTLTKAGFKKLTIFDDGKQVLDKLLELVEKKGEDFTEDVQILITDIEMPQMDGHTLTRKVKEHPILKRLPVIIFSSLITKDLKHKGTSVGADEQLSKPDIGELVNIIDNYIE
>NZ_CP013850.1|WP_003358979.1|2429066_2429921_-|4Fe-4S-binding-protein
MKMISKNEIAKLKGEGFLAQKQEGYFSVRILSRAGNFTSKQIIKLAEIADNYGKGYLGVTTRLATEIPWIKYEDIEAVKKEIVSSGMGHGGTGKKVRPLVSCKGTVCVHGLYDTQKLCGELHDKYFGYELPSKFKITLVGCPNNCAKASINDIGIMGQAYVEFNEEKCKACGICTKSCRQKAVTVENNKIVYKKDLCVNCGKCATVCPFEAMTIKEQGLQVYLGGRFGREYRIGNRLKGLYKEEEIPALVQKIFDVYSEMGNPGERLAKMIERVGFDKVEEAIL
>NZ_CP013850.1|WP_075143871.1|2430386_2431967_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MITVTNLSLRYGDKKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILSGEIEANTGDVSIQPGVRMSILKQDHFKYDEFPVLETVIMGNERLYQIMKEKDAIYAKTPFTDEDGIRASELEGEFAELNGWEAEAEASSLLQGLGIGTELHEKNMKDLSGSEKVKVLLAQALFGNPGVLILDEPTNHLDIKSVNWLEEFLINFEGTVIVVSHDRHFLNKVCTHMADVDFGKIKLYVGNYDFWYESSQLALQMAKDQNKKKEEKIKELQEFIARFSANASKSKQATSRKKLLDKIDLDNIQPSSRKYPYIAFKPEREVGNDILRVEGLTKTIDGTKVLDNISFIIGKDDKIAFVGDELSITTLFKIISGELKPDSGEYKWGITITNAYFPKDNSEYFNDVDLNLVDWLRQYSEEKSESYLRGFLGRMLFSGEEALKEVKVLSGGEKVRCMLSKMMLNNANVIILDQPTNHLDLESITALNNGLMDYKSNILFTSHDHQFIQTIANRIIEVSEAKFVDKKVTYDEYLESK
>NZ_CP013850.1|WP_085320770.1|2432229_2434233_-|methyl-accepting-chemotaxis-protein
MKFKTMKGKMLTYFLSLFLIICIAISFMAYFMSKRMIERKASSLMSEVSRQAVQNIEARLNGTLDSIETVANMPTIKDPKLGWDKKKTILDEEIKLHGHIKMGIVSKEGQSIQTDGTTVNVKDRPYFKKAMEGKSTISEPIVSKVDGKVVIIYTVPIKNGTIIMGALTAVRAGNDISNISNSIKVGESGGAYLIDSTGTVIAHKNKESVIKRENSIKDAQSNEELKPIAAIEKSMIEGKEGIGQYKYKGAEKYISYSPMKSTGWSLAIYAPKNEILKEVSEITRNIIIVSTLGIGIALVCIWFISTQISNNLISMRDSLNIVATGDLTTNVDSNIEKEKDEIGHMARALSKTVLSIGNMINSLKGSSFNIDDKANNLAAISEEFTATTENVSTAIQEVATGATNQAQALTEIVSMLNDFSDKINSTVNNIEEIDGMSKEIDEKANISNKDMKELLNSIENLTKVFENFETKIWTMESNVQKINEITNLINDIAEKTNLLALNAAIEAARAGESGKGFAVVAEEIRKLAEMSRKSSEDIYTIVNGVLEDTKDMVKSSNEVNEKLNGQRSTADEAMNSFMEISKSVTNMIPKIRNINNSANIIEKNKNEILNKSETIASISQEISASAEEISASSEEMSASSEEVANTAQSLNEMTQGMLNEMNKFKTE
>NZ_CP013850.1|WP_061309457.1|2435459_2436095_+|SafA/ExsA-family-spore-coat-assembly-protein
MKKSLLKKILFPVLLTSFLCLFKGIRVSAADYTSYIVVSGDSLWKISVKYQIELKEIIEANPQIKNTDLIYPEEKINIPNIDTIKALENEIISLVNIERENVGLPHLRTNWQLSKVARYKSQDMATKSYFSHISSTYGSPSTMLQNFNIRSITTGENIAYGQRIPQQVMTSLMDSIDDRQNILSNAYTEIGVGLYKSSSGVYYWTQLFIKP
>NZ_CP013850.1|WP_061309456.1|2436238_2437198_-|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase
MNYYCNNEPYVLVFGASVVDIFGFSCCDYRAYNSNPGKIKISFGGVCRNIAENLSRVGINTKFISILGEDENAKCMLEHSRKMGYDMGDSLILKGGTTPTYMAILDENGEMVSAVADMKSIDKMNCEFIDSKADIIKKAEYTVLDSDNPEILEYILKKFKGKTEFILDPVSAEKSKKIKHLIKYFHTIKPNIHEAEVLSGFKIETTEDLKKAGEYFRSLGVENVFISLDAEGIYYKNKFEEGRIKANDVTVKNVTGAGDAFVAGIAYSYMNKLSLEETVKFAIAMANLTIAHENTINPDLSYNIVENNIENIQWIEEYL

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Crispr_ID: NZ_CP013850_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP013850_7

2470639-2471853

Orphan

III-B

Consensus_repeat	Method
ATTTAAATACATCTCATGTTAATGTTCAAT	CRISPRCasFinder
ATTTAAATACATCTNATGTTAATGTTCAA	CRT

18 spacers

The CRISPR arrays of NZ_CP013850_7

>merge|NZ_CP013850|7|2470639-2471853|CRISPRCasFinder,CRT
TTAATAATACATCTTATGTTATTGTTCAACTTGAAAATCAGATAGACAACATTAATCAAACAGTACAATTTAAATACATCTCATGTTATTGTTCAACCTGAAAGAGTTAATCTAAATCATATAGATAAAATTTGATTTAAATACATCTTATGTTAATGTTCAACAAAATGGTTAGTAGAACGTAATAAAGTGGATAAATAATTTAAATACATCCTATATTAATGTTCAACATATTTAAGAGGTAAAACTTTAGCAGGAGCTTATTGATTTAAATACATTCTATGTTAATGTTCAACCAAGAGATACAAGCTAGAAAATTGGTTCTTATAAAATTTAAATACATCCTATGTTAATGTTCAACGAAATGCCTTTGTTCTTTCAGAATTACAAAGAGAAGTATTTAAATACATCTCATGTTAATGTTCAACAACTACGCTTTGGAGTACACTACAGACATTACAGCATTTAAATACATCTCATGTTATTGTTCAACTGTTCAAAGTAGAAAAGTTTATATTAATAGATTAAAATTTAAATACATCCTATGTTAATGTTCAACCTTTGATGTAGACGGTATTACTAGATTAGGTGGAAAATTTAAATACATCCTATGTTAATGTTCAACTTAATACAATCGCTAGTAAATACGAATCAATAAGCTAATTTAAATACATCTTATGTTAATGTTCAACTGTTAAAGAACTTGATAAATATGTAATAGGTCAATGATTTAAATACATCTCATGTTAATGTCCAACCAAGAGAGTTTAAGATTAATAGATTCCCTAAAAAATTTAAATACATCTCATGTTAATGTTCAACTATATATATATTTGCAGAACTAAAACAACAAGTCGGATTTAAATACATCTCATGTTAATGTTCAATTTAGTTTTAGAAGCTCATAATAATATAAGACCATATTTAAATACATCTCATGTTAATGTTCAATGATACAGAGTTTAGGGAACGTTATAAGGCTTCAGATTTAAATACATCTCATGTTAATGTTCAATTGATTATGATTCTAAAAAACAGATTAAAAGCTATATATTTAAATACATCTCATGTTAATGTTCAATATATACACCAATACAGCAGGGAGGGTGCGAAAGTGAATTTAAATACATCTCATGTTAATGTTCAATTGATATCGAGGTGATAAGCAATGGCGAATAATGAATCATTTAAATACATCTCATGTTAATGTTCAAT

>NZ_CP013850|7|7|2470639-2471853|CRISPRCasFinder
TTAATAATACATCTTATGTTATTGTTCAAC	TTGAAAATCAGATAGACAACATTAATCAAACAGTACA
ATTTAAATACATCTCATGTTATTGTTCAAC	CTGAAAGAGTTAATCTAAATCATATAGATAAAATTTG
ATTTAAATACATCTTATGTTAATGTTCAAC	AAAATGGTTAGTAGAACGTAATAAAGTGGATAAATA
ATTTAAATACATCCTATATTAATGTTCAAC	ATATTTAAGAGGTAAAACTTTAGCAGGAGCTTATTG
ATTTAAATACATTCTATGTTAATGTTCAAC	CAAGAGATACAAGCTAGAAAATTGGTTCTTATAAA
ATTTAAATACATCCTATGTTAATGTTCAAC	GAAATGCCTTTGTTCTTTCAGAATTACAAAGAGAAGT
ATTTAAATACATCTCATGTTAATGTTCAAC	AACTACGCTTTGGAGTACACTACAGACATTACAGC
ATTTAAATACATCTCATGTTATTGTTCAAC	TGTTCAAAGTAGAAAAGTTTATATTAATAGATTAAA
ATTTAAATACATCCTATGTTAATGTTCAAC	CTTTGATGTAGACGGTATTACTAGATTAGGTGGAAA
ATTTAAATACATCCTATGTTAATGTTCAAC	TTAATACAATCGCTAGTAAATACGAATCAATAAGCTA
ATTTAAATACATCTTATGTTAATGTTCAAC	TGTTAAAGAACTTGATAAATATGTAATAGGTCAATG
ATTTAAATACATCTCATGTTAATGTCCAAC	CAAGAGAGTTTAAGATTAATAGATTCCCTAAAAA
ATTTAAATACATCTCATGTTAATGTTCAAC	TATATATATATTTGCAGAACTAAAACAACAAGTCGG
ATTTAAATACATCTCATGTTAATGTTCAAT	TTAGTTTTAGAAGCTCATAATAATATAAGACCAT
ATTTAAATACATCTCATGTTAATGTTCAAT	GATACAGAGTTTAGGGAACGTTATAAGGCTTCAG
ATTTAAATACATCTCATGTTAATGTTCAAT	TGATTATGATTCTAAAAAACAGATTAAAAGCTATAT
ATTTAAATACATCTCATGTTAATGTTCAAT	ATATACACCAATACAGCAGGGAGGGTGCGAAAGTGA
ATTTAAATACATCTCATGTTAATGTTCAAT	TGATATCGAGGTGATAAGCAATGGCGAATAATGAATC
ATTTAAATACATCTCATGTTAATGTTCAAT

>NZ_CP013850|7|2|2470639-2471852|CRT
TTAATAATACATCTTATGTTATTGTTCAA	CTTGAAAATCAGATAGACAACATTAATCAAACAGTACA
ATTTAAATACATCTCATGTTATTGTTCAA	CCTGAAAGAGTTAATCTAAATCATATAGATAAAATTTG
ATTTAAATACATCTTATGTTAATGTTCAA	CAAAATGGTTAGTAGAACGTAATAAAGTGGATAAATA
ATTTAAATACATCCTATATTAATGTTCAA	CATATTTAAGAGGTAAAACTTTAGCAGGAGCTTATTG
ATTTAAATACATTCTATGTTAATGTTCAA	CCAAGAGATACAAGCTAGAAAATTGGTTCTTATAAA
ATTTAAATACATCCTATGTTAATGTTCAA	CGAAATGCCTTTGTTCTTTCAGAATTACAAAGAGAAGT
ATTTAAATACATCTCATGTTAATGTTCAA	CAACTACGCTTTGGAGTACACTACAGACATTACAGC
ATTTAAATACATCTCATGTTATTGTTCAA	CTGTTCAAAGTAGAAAAGTTTATATTAATAGATTAAA
ATTTAAATACATCCTATGTTAATGTTCAA	CCTTTGATGTAGACGGTATTACTAGATTAGGTGGAAA
ATTTAAATACATCCTATGTTAATGTTCAA	CTTAATACAATCGCTAGTAAATACGAATCAATAAGCTA
ATTTAAATACATCTTATGTTAATGTTCAA	CTGTTAAAGAACTTGATAAATATGTAATAGGTCAATG
ATTTAAATACATCTCATGTTAATGTCCAA	CCAAGAGAGTTTAAGATTAATAGATTCCCTAAAAA
ATTTAAATACATCTCATGTTAATGTTCAA	CTATATATATATTTGCAGAACTAAAACAACAAGTCGG
ATTTAAATACATCTCATGTTAATGTTCAA	TTTAGTTTTAGAAGCTCATAATAATATAAGACCAT
ATTTAAATACATCTCATGTTAATGTTCAA	TGATACAGAGTTTAGGGAACGTTATAAGGCTTCAG
ATTTAAATACATCTCATGTTAATGTTCAA	TTGATTATGATTCTAAAAAACAGATTAAAAGCTATAT
ATTTAAATACATCTCATGTTAATGTTCAA	TATATACACCAATACAGCAGGGAGGGTGCGAAAGTGA
ATTTAAATACATCTCATGTTAATGTTCAA	TTGATATCGAGGTGATAAGCAATGGCGAATAATGAATC
ATTTAAATACATCTCATGTTAATGTTCAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP013850.1\|WP_012344341.1\|2468030_2468585_-\|hemerythrin-domain-containing-protein	unknown	unknown	gnl\|CDD\|226454
NZ_CP013850.1\|WP_076178048.1\|2460924_2461809_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235853
NZ_CP013850.1\|WP_012721426.1\|2470005_2470200_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013850.1\|WP_085320752.1\|2472883_2473303_-\|phage-holin-family-protein	unknown	unknown	gnl\|CDD\|377457
NZ_CP013850.1\|WP_085321037.1\|2477306_2477651_-\|DUF2577-domain-containing-protein	unknown	unknown	gnl\|CDD\|378501
NZ_CP013850.1\|WP_003385957.1\|2463097_2464438_-\|NCS2-family-permease	unknown	unknown	gnl\|CDD\|225161
NZ_CP013850.1\|WP_085321038.1\|2477653_2478628_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013850.1\|WP_085320755.1\|2469470_2469638_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|235203
NZ_CP013850.1\|WP_085321034.1\|2475193_2475820_-\|DUF2313-domain-containing-protein	unknown	unknown	gnl\|CDD\|378379
NZ_CP013850.1\|WP_085321039.1\|2478639_2479317_-\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|236880
NZ_CP013850.1\|WP_025776446.1\|2462024_2462858_-\|DUF975-family-protein	unknown	unknown	gnl\|CDD\|283754
NZ_CP013850.1\|WP_085320758.1\|2464525_2465998_-\|CZB-domain-containing-protein	unknown	unknown	gnl\|CDD\|214599
NZ_CP013850.1\|WP_085320757.1\|2466423_2467593_-\|alanine-racemase	unknown	unknown	gnl\|CDD\|143481
NZ_CP013850.1\|WP_085320753.1\|2472068_2472839_-\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|119407
NZ_CP013850.1\|WP_085320754.1\|2469775_2470021_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013850.1\|WP_085321036.1\|2476895_2477303_-\|DUF2634-domain-containing-protein	unknown	unknown	gnl\|CDD\|378510
NZ_CP013850.1\|WP_085321035.1\|2475800_2476895_-\|baseplate-J/gp47-family-protein	unknown	unknown	gnl\|CDD\|377414
NZ_CP013850.1\|WP_085320756.1\|2468617_2469238_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013850.1\|WP_085320751.1\|2473393_2473609_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP013850.1\|WP_012704076.1\|2473624_2473930_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP013850.1\|WP_012344341.1\|2468030_2468585_-\|hemerythrin-domain-containing-protein	gnl\|CDD\|226454	COG3945, COG3945, Uncharacterized conserved protein [Function unknown].	2.34557e-45
NZ_CP013850.1\|WP_076178048.1\|2460924_2461809_+\|SDR-family-oxidoreductase	gnl\|CDD\|235853	PRK06701, PRK06701, short chain dehydrogenase; Provisional.	3.80778e-164
NZ_CP013850.1\|WP_085320752.1\|2472883_2473303_-\|phage-holin-family-protein	gnl\|CDD\|377457	pfam05105, Phage_holin_4_1, Bacteriophage holin family. Phage holins and lytic enzymes are both necessary for bacterial lysis and virus dissemination. This family also includes TcdE/UtxA involved in toxin secretion in Clostridium difficile. The 1.E.10 family is represented by Bacillus subtilis phi29 holin; 1.E.16 represents the Cph1 holin; and the 1.E.19 family is represented by the Clostridium difficile TcdE holin. Toxigenic strains of C. difficile produce two large toxins (TcdA and TcdB) encoded within a pathogenicity locus. tcdE, encoded between tcdA and tcdB, encodes a 166 aa protein which causes death to E. coli when expressed, and the structure of TcdE resembles holins. TcdE acts on the bacterial membrane. Since TcdA and TcdB lack signal peptides, they may be released via TcdE either prior to or subsequent to cell lysis.	2.51096e-43
NZ_CP013850.1\|WP_085321037.1\|2477306_2477651_-\|DUF2577-domain-containing-protein	gnl\|CDD\|378501	pfam10844, DUF2577, Protein of unknown function (DUF2577). This family of proteins has no known function.	4.19335e-37
NZ_CP013850.1\|WP_003385957.1\|2463097_2464438_-\|NCS2-family-permease	gnl\|CDD\|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	1.78906e-119
NZ_CP013850.1\|WP_085320755.1\|2469470_2469638_-\|transcriptional-regulator	gnl\|CDD\|235203	PRK04024, PRK04024, 2,3-bisphosphoglycerate-independent phosphoglycerate mutase.	0.00509445
NZ_CP013850.1\|WP_085321034.1\|2475193_2475820_-\|DUF2313-domain-containing-protein	gnl\|CDD\|378379	pfam10076, DUF2313, Uncharacterized protein conserved in bacteria (DUF2313). Members of this family of proteins comprise various hypothetical and putative bacteriophage tail proteins.	8.26136e-14
NZ_CP013850.1\|WP_085321039.1\|2478639_2479317_-\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|236880	PRK11198, PRK11198, LysM domain/BON superfamily protein; Provisional.	2.27491e-16
NZ_CP013850.1\|WP_025776446.1\|2462024_2462858_-\|DUF975-family-protein	gnl\|CDD\|283754	pfam06161, DUF975, Protein of unknown function (DUF975). Family of uncharacterized bacterial proteins.	3.62936e-34
NZ_CP013850.1\|WP_085320758.1\|2464525_2465998_-\|CZB-domain-containing-protein	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	3.4695e-30
NZ_CP013850.1\|WP_085320757.1\|2466423_2467593_-\|alanine-racemase	gnl\|CDD\|143481	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase. This family includes predominantly bacterial alanine racemases (AR), some serine racemases (SerRac), and putative bifunctional enzymes containing N-terminal UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase (murF) and C-terminal AR domains. These proteins are fold type III PLP-dependent enzymes that play essential roles in peptidoglycan biosynthesis. AR catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. SerRac converts L-serine into its D-enantiomer (D-serine) for peptidoglycan synthesis. murF catalyzes the addition of D-Ala-D-Ala to UDPMurNAc-tripeptide, the final step in the synthesis of the cytoplasmic precursor of bacterial cell wall peptidoglycan. Members of this family contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. AR and other members of this family require dimer formation and the presence of the PLP cofactor for catalytic activity. Fungal ARs and eukaryotic serine racemases, which are fold types I and II PLP-dependent enzymes respectively, are excluded from this family.	0
NZ_CP013850.1\|WP_085320753.1\|2472068_2472839_-\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|119407	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.	2.75724e-34
NZ_CP013850.1\|WP_085321036.1\|2476895_2477303_-\|DUF2634-domain-containing-protein	gnl\|CDD\|378510	pfam10934, DUF2634, Protein of unknown function (DUF2634). Some members in this family of proteins are annotated as phage related, xkdS however currently there is no known function.	6.43774e-35
NZ_CP013850.1\|WP_085321035.1\|2475800_2476895_-\|baseplate-J/gp47-family-protein	gnl\|CDD\|377414	pfam04865, Baseplate_J, Baseplate J-like protein. The P2 bacteriophage J protein lies at the edge of the baseplate. This family also includes a number of bacterial homologs, which are thought to have been horizontally transferred.	1.62958e-64

>NZ_CP013850.1|WP_012721426.1|2470005_2470200_-|hypothetical-protein
MNDKKSPQTIANQNWEKKNREYASYLKSRSSARSFIRNKATLEDIEELRNLLKEREGNLKCERE
>NZ_CP013850.1|WP_085320754.1|2469775_2470021_-|hypothetical-protein
MRKGIRYLIVGLLLGASTRFVGVAKAIEPSEDNCPENGEYMYCLDKTTPLWISIYDVHQEEKFIYLRQPNSNKIIKLVELK
>NZ_CP013850.1|WP_085320755.1|2469470_2469638_-|transcriptional-regulator
MSSFYRAKEVAEILDVSTTKAYRIIRQLNKELKEMGYITIAGRVPIKYFKEKYYC
>NZ_CP013850.1|WP_085320756.1|2468617_2469238_-|hypothetical-protein
MGKVHYWLYNKITWFEELEKEIINFAEIKNLPVKQWKEEIISKYGVPTENKSLEEIIDTSNIHGWLQNKIHSAEARQAAWVTAILKEKKEYKKDLIDIFKSQGEKCALEYREKNHPIYAEDMYNALNDYILEGMPCDRINVILESNENEILWKANKCLHTPHWETVGGEVENFYSLREGWISAFINSLNNKFHFKSLGNYTYSIKK
>NZ_CP013850.1|WP_012344341.1|2468030_2468585_-|hemerythrin-domain-containing-protein
MNSIELMVNEHKNIKHMLVVIRKYCFKVLKNEQVDYNDFYKIIDFVRNYADKHHHGKEEDYLFNRMIEEIKGPTEKLVKQGMLVEHDLGRLYMQNLEKALKALENGEEEAKIDIIANAVSYTDLLYRHIEKEDDVVYKFAERNLSKETLKRLDEDCERIEKEAREKGIQDKYKNLIHELEEKVK
>NZ_CP013850.1|WP_085320757.1|2466423_2467593_-|alanine-racemase
MFRNHRPVWEEVNLDNLSYNMRNIKKKVNCKEIFAVVKANGYGHGALDIASTLLENGATRLSVACLSEATELRKGGITCPINILGITPPTLFEDIIDYNIEPVVFSYDYANQLSKAASLKNRIVKTHIAVDTGMGRLGFDPTVESLEEIKRIQDLSNIKIEGLCSHFSSSDEKDKSYSEYQFKIFQNFREKLIEMNMRIPIHHMSNSAAIIDLPSTYLDAVRAGIILYGYYPSMEVNKENLHIKQVMTLKANIVHIKTIDSGRYVGYNRKFKTKRKSKIAILPLGYGDGYTRFLSNRGKVIINGQYAPIVGNICMDQCMIDVTDIKEVKVGDEVIIIGKDNINNLRYDAEDIASKVGMTSGEIMSIISKRVPRVYIKNGNIVKVRNYIA
>NZ_CP013850.1|WP_085320758.1|2464525_2465998_-|CZB-domain-containing-protein
MRIFKNNAIEKEIIKISQDFQNQNVHALDEIEGSTSKNRMVRFTAGIAKIVQVISPKVKKLINGVLSITTRISTFSVNLDYSGEHLKKSADKLYNSSGVLNSSIKEVKEAMQQITLAIEEDVETVEHISSGNIELIKYMDENKKNLGLVKNVNKELEFKAQSMEKDMTELNSILENMKTIVTGMSEIASKTNLLALNASIEAARAGEAGKGFAVVAEEVRKLSESTSKQLEKMEEFVNNIGTCSTNSSKSVKDTIGSIGELGEYTQAISSSSSKVREAIDIEVKSIELLAASMQEINASSEEINSNMDIIGENVQEVSKEAAVLSEKSLEIKYLADEMDKIDDEVSNLAKLSGDITGENYFKITNKDFIVAIDNAIKAHENWVQQLQNMAMENKIKPIQTDGQKCGFGHFYNSVMPRNEKIKEIWIKIDNIHKELHKVGGIVKSNIKDGHTEKAKENSKKATQLSQTIISMLSHIKSIAIETDKEGNLVL
>NZ_CP013850.1|WP_003385957.1|2463097_2464438_-|NCS2-family-permease
MGGRGIKEKDEGEVENKFNSLFNIKKYNTTVKGEILAGFTSFFAIVYIIAVNASILSDAGLPLEGAIIATVLSSFVGCILVGVISNAPLILVPGMGVNALFSYTIVGSMGLSWQQALAAVFVSGVVFSIIAFTRFSKTLIESIPTSLKEAITVGIGVLITFIGLQKSGIVIGSTTTFVALGHFNNPLVYVTFINLIITLILFIKNVPGNFLISMIVGTIISYFFGLIDMAKLTFSNFSLGAYKEVFFKMDFSSATSITFWIAVFSLTLVLVFENLGLLHAHINVMLKEENKFKTSFKACSLSAITCGFFGTSPTVATIETAAGITAGGKTGLTSIFTGILFLLSLFLLPIIKIIPNSAISPILIVIGGLMIKNILSINFNDFSEGFPAFLIIVMIPLTFSIVDGMAFGFICYPIVKLAGKKSKEISYAMYIISLMFLLNFILHAVS
>NZ_CP013850.1|WP_025776446.1|2462024_2462858_-|DUF975-family-protein
MEEKTILSNSQIKSKAKEALKGNWGTAVIAFIIFNIVMYSVNYVYNINQISNYIHDPYLVRENAGFGASGILFFIKLLLAGPMTYGITKFSMNLVRDKSHKIENIFEGFKHFSGTFIMNIVLGIYSFLWSLLLFIPFFAIVFVMVIREFSKTNMNFYSTGNDFSGWMIAIFILLIIVLTVALSMILFRYAMTYYIYIDNPDMGAMEAIKESVSMMKGNKTRLLLLYLSFILWYLLGIVTVGIAFLWITPYIKSTEAVFYDELKKSNEHNADEAVSAL
>NZ_CP013850.1|WP_076178048.1|2460924_2461809_+|SDR-family-oxidoreductase
MNEDLNFINSFPKSVPGQEQSKQPGIEAIMNPKPIFDNPNYKASAKLMDRVALITGGDSGIGRAVAVTFAKEGADISIVYFDEHEDAKETQAIIEGLGRKCLLIPGDITDDNFCNNAINQTINTFNKLDILVNNAAVQYVQNSIEDITKEQLEKTFKTNIFSIFYLVKAALPYLNRGASIINTASITAYKGQKLLIDYSSSKGAIVSFTRSLALSLWGKGIRVNAVAPGPIWTPLIPASFDTNHVETFGSTTTMGRPGQPVELAPSYVYLASNECASFVSGEVIHINGGEIING
>NZ_CP013850.1|WP_085320753.1|2472068_2472839_-|N-acetylmuramoyl-L-alanine-amidase
MLFNLNPGHTLSGGDVGTRGIGELKEEVLTRQLVGEIDKELRGRGHSTNICRVDYASTLQESLNKQVALCNSVNADLNICIHFNTTVGGYGSEVYTYGGKYLVEADRVLKQLNNLGFRNRGIKDQPLALTKRTKAKTIYIEVCFIDSSGDVAILNKYGMNGIAKSIVNGVLGTSSNVTPAPSEPTNNNSWINLDGKTGTINTPSGVNIREKKSTSSKILGALPNGAKVNLYRKEGDWIHIYYPPHGGYVYAKYIRY
>NZ_CP013850.1|WP_085320752.1|2472883_2473303_-|phage-holin-family-protein
MEKQKIFNIIVATVGTWFTWLFGAWDTALIVLICFMVLDYCTGLLRGAVNKELSSDVGLKGIARKAVIFIVLIVAVLLDRLLNTGNWVFRSLVAYFYIANEGISLLENCAQLGVPIPDKLKDMLVQLKEGNKKEIKEQE
>NZ_CP013850.1|WP_085320751.1|2473393_2473609_-|hypothetical-protein
MILYDLLKNLINNNYYEKEDMNNKLNVFYTFNQINLEQYSELMATVNPAEKEDLGNRGLDVENTTEEVVTQ
>NZ_CP013850.1|WP_012704076.1|2473624_2473930_-|hypothetical-protein
MKRGSLIIYDNSGKVWVNTGDAEGCIPPHTPPDGLPYIITEFGEFNDKIIKGIDVTVTPHKLITEDIPHIETEEEKLKKELLKAQSEVVNLKYKEVLNNIK
>NZ_CP013850.1|WP_085321034.1|2475193_2475820_-|DUF2313-domain-containing-protein
MKKKLIDFLPPQISDIEEFKNIMATENIELELIEKCQERILKENFIDTATDYGIKHKEQLFKIRADLVNDTLEFRKLRIKNRKMDKMPITQRALEHKLKTLFGEGNYKVEVLNDEYVLKVEINTFDWSMFNEIIDNFRYIIPCNMMLSSTLVQKINTNIYFASAITSGEEITVYPWMPKDIASNGKVNIAMGSNTGVENITVYPRKEA
>NZ_CP013850.1|WP_085321035.1|2475800_2476895_-|baseplate-J/gp47-family-protein
MFEDQTEEAVLARMMNKISNDLDKREGSLLYNALAPAAQEVAKMYSDMDYFLKCTFASPDMPDELLDLRVAEEGLKREKATYAIKKGYFYNEENELIDIPLNSRFSIEDFNFIAIEKISTGLYKMQCETTGIEGNHVTGSLIPIEYIEDLSIATLGELIIPGEDVESNQSLYDRYIEHLNEKPYGGNIADYKIRTRVIEGVGTVKVFPIWNGGGTVKIVFLDSDYSVPTKELIDKVQTILDPVQNQGKGFGIAPVGHVVTVLGAKDIEITIETKLLLKRGLTIGQVQEDIEKVIKDYLLNLRKQWHEDDNTIVRISQIEARILNVEGVADLFNTKINGKEENLTLESEEVPILKEVVLSEKEIN
>NZ_CP013850.1|WP_085321036.1|2476895_2477303_-|DUF2634-domain-containing-protein
MSEVSILPQGAIIDEDIEVEEIIEPTKTYKIKDNRIVGFTDGKEALKQAIQLILGTERYEYLIYSWNYGSELNGLIGKQKDIAESEFKRRIKEALRQDDRINNVDNFIFNYDKDGVEVSFTVFSIYGEFTESVVR
>NZ_CP013850.1|WP_085321037.1|2477306_2477651_-|DUF2577-domain-containing-protein
MGIIDTIKKASMGAVGASNPVNISFGEIVSTNELKIKVDQKLILDRDFFIIPESLTRYEVDLKHSHTYINNSIESNLNTSLDKLLIREDLKQGDKVLLLRVQGGQQYVILDKVV
>NZ_CP013850.1|WP_085321038.1|2477653_2478628_-|hypothetical-protein
MNIQLLLDNKDGNVFDISELVNEVTWKTKRKDKPSSLNFEILKDKQITINNGDVISFKVDNNPVFYGYAFENGGSRNPITKITAYDQLRYLLFNDTYVFKNKKASQILMQIAKDIGLRVGTIEDTGYVIPQLLEDDKKLLDIIYSSLEKTLLNSKKTYTLYDDFGYLNLRNINNLRQEVVISDDNNLGDYDWKNSIDSDTYNRVKIVRDNKDTKGRDVYIAQDSRNIARWGRLQYFKKVDEKMNKAQIQEMVNAALKLKNRETKTLKLKDVISTDIAADLKLRAGSGVYVDIKEKGIKQYYLIEEATHKFQKGNLVMDFDLKVV
>NZ_CP013850.1|WP_085321039.1|2478639_2479317_-|LysM-peptidoglycan-binding-domain-containing-protein
MYKMYLGINDGEEGFILPVLTEKIEFDEDGNNKTYDIINLGEINTINKPKLMEISFESFFPKHKGPYVSSEQLFEPSFYIAKIREWRDKKQKIRFIFTGSPLEINDLFTIENFKPSEEGGEVGDVHYSIGLKRYKNYSAKKVVIVTPKTAAANQSVKKVIANPKTTRPNNTNKPKTHTVSGNDTLWHISKKYLGDGNKWPQIYNLNKDKIKDPNLIYTGQVLRLP

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP013850_4	4.2\|2025028\|21\|NZ_CP013850\|PILER-CR	2025028-2025048	21	NZ_CP006909	Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence	5039-5059	0	1.0
NZ_CP013850_4	4.2\|2025028\|21\|NZ_CP013850\|PILER-CR	2025028-2025048	21	NZ_CP013700	Clostridium botulinum strain AM1195 plasmid pRSJ11_1, complete sequence	84494-84514	0	1.0
NZ_CP013850_7	7.18\|2471787\|37\|NZ_CP013850\|CRISPRCasFinder	2471787-2471823	37	NZ_CP014173	Clostridium botulinum strain B609 plasmid pRSJ22_2, complete sequence	15264-15300	0	1.0
NZ_CP013850_4	4.2\|2025028\|21\|NZ_CP013850\|PILER-CR	2025028-2025048	21	NZ_CP013700	Clostridium botulinum strain AM1195 plasmid pRSJ11_1, complete sequence	36495-36515	1	0.952
NZ_CP013850_4	4.2\|2025028\|21\|NZ_CP013850\|PILER-CR	2025028-2025048	21	NZ_CP013684	Clostridium botulinum strain AM282 plasmid pRSJ10_1, complete sequence	100925-100945	1	0.952
NZ_CP013850_4	4.2\|2025028\|21\|NZ_CP013850\|PILER-CR	2025028-2025048	21	NC_025146	Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111	79775-79795	1	0.952
NZ_CP013850_4	4.2\|2025028\|21\|NZ_CP013850\|PILER-CR	2025028-2025048	21	NC_010418	Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence	83403-83423	1	0.952
NZ_CP013850_7	7.8\|2471132\|36\|NZ_CP013850\|CRISPRCasFinder	2471132-2471167	36	NZ_CP014152	Clostridium botulinum strain BrDura plasmid pRSJ20_1, complete sequence	102193-102228	1	0.972
NZ_CP013850_7	7.8\|2471132\|36\|NZ_CP013850\|CRISPRCasFinder	2471132-2471167	36	NZ_CP006909	Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence	188033-188068	1	0.972
NZ_CP013850_7	7.8\|2471132\|36\|NZ_CP013850\|CRISPRCasFinder	2471132-2471167	36	NZ_CP013684	Clostridium botulinum strain AM282 plasmid pRSJ10_1, complete sequence	79741-79776	1	0.972
NZ_CP013850_7	7.8\|2471132\|36\|NZ_CP013850\|CRISPRCasFinder	2471132-2471167	36	NZ_CP013710	Clostridium botulinum strain F634 plasmid pRSJ2_3, complete sequence	177157-177192	1	0.972
NZ_CP013850_7	7.8\|2471132\|36\|NZ_CP013850\|CRISPRCasFinder	2471132-2471167	36	NC_010379	Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence	113600-113635	1	0.972
NZ_CP013850_7	7.15\|2471591\|34\|NZ_CP013850\|CRISPRCasFinder	2471591-2471624	34	NZ_CP031100	Clostridium botulinum strain CFSAN034202 plasmid p1_CFSAN034202, complete sequence	53550-53583	1	0.971
NZ_CP013850_7	7.15\|2471591\|34\|NZ_CP013850\|CRISPRCasFinder	2471591-2471624	34	NZ_CP014173	Clostridium botulinum strain B609 plasmid pRSJ22_2, complete sequence	15845-15878	1	0.971
NZ_CP013850_7	7.33\|2471590\|35\|NZ_CP013850\|CRT	2471590-2471624	35	NZ_CP031100	Clostridium botulinum strain CFSAN034202 plasmid p1_CFSAN034202, complete sequence	53550-53584	1	0.971
NZ_CP013850_7	7.33\|2471590\|35\|NZ_CP013850\|CRT	2471590-2471624	35	NZ_CP014173	Clostridium botulinum strain B609 plasmid pRSJ22_2, complete sequence	15845-15879	1	0.971
NZ_CP013850_7	7.36\|2471786\|38\|NZ_CP013850\|CRT	2471786-2471823	38	NZ_CP014173	Clostridium botulinum strain B609 plasmid pRSJ22_2, complete sequence	15264-15301	1	0.974
NZ_CP013850_4	4.4\|2024997\|35\|NZ_CP013850\|CRISPRCasFinder	2024997-2025031	35	NZ_CP013700	Clostridium botulinum strain AM1195 plasmid pRSJ11_1, complete sequence	84483-84517	2	0.943
NZ_CP013850_4	4.4\|2024997\|35\|NZ_CP013850\|CRISPRCasFinder	2024997-2025031	35	NZ_CP013710	Clostridium botulinum strain F634 plasmid pRSJ2_3, complete sequence	28409-28443	2	0.943
NZ_CP013850_4	4.4\|2024997\|35\|NZ_CP013850\|CRISPRCasFinder	2024997-2025031	35	NZ_CP014152	Clostridium botulinum strain BrDura plasmid pRSJ20_1, complete sequence	9866-9900	2	0.943
NZ_CP013850_7	7.8\|2471132\|36\|NZ_CP013850\|CRISPRCasFinder	2471132-2471167	36	NC_010418	Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence	95468-95503	2	0.944
NZ_CP013850_7	7.14\|2471527\|34\|NZ_CP013850\|CRISPRCasFinder	2471527-2471560	34	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	183039-183072	2	0.941
NZ_CP013850_7	7.26\|2471131\|37\|NZ_CP013850\|CRT	2471131-2471167	37	NZ_CP014152	Clostridium botulinum strain BrDura plasmid pRSJ20_1, complete sequence	102193-102229	2	0.946
NZ_CP013850_7	7.26\|2471131\|37\|NZ_CP013850\|CRT	2471131-2471167	37	NZ_CP006909	Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence	188033-188069	2	0.946
NZ_CP013850_7	7.26\|2471131\|37\|NZ_CP013850\|CRT	2471131-2471167	37	NZ_CP013684	Clostridium botulinum strain AM282 plasmid pRSJ10_1, complete sequence	79741-79777	2	0.946
NZ_CP013850_7	7.26\|2471131\|37\|NZ_CP013850\|CRT	2471131-2471167	37	NZ_CP013710	Clostridium botulinum strain F634 plasmid pRSJ2_3, complete sequence	177156-177192	2	0.946
NZ_CP013850_7	7.26\|2471131\|37\|NZ_CP013850\|CRT	2471131-2471167	37	NC_010379	Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence	113599-113635	2	0.946
NZ_CP013850_4	4.4\|2024997\|35\|NZ_CP013850\|CRISPRCasFinder	2024997-2025031	35	NZ_CP006909	Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence	5036-5070	3	0.914
NZ_CP013850_4	4.4\|2024997\|35\|NZ_CP013850\|CRISPRCasFinder	2024997-2025031	35	NC_010418	Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence	79434-79468	3	0.914
NZ_CP013850_4	4.4\|2024997\|35\|NZ_CP013850\|CRISPRCasFinder	2024997-2025031	35	NC_010379	Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence	102786-102820	3	0.914
NZ_CP013850_7	7.8\|2471132\|36\|NZ_CP013850\|CRISPRCasFinder	2471132-2471167	36	NZ_CP006909	Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence	193770-193805	3	0.917
NZ_CP013850_7	7.8\|2471132\|36\|NZ_CP013850\|CRISPRCasFinder	2471132-2471167	36	NC_025146	Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111	68983-69018	3	0.917
NZ_CP013850_7	7.8\|2471132\|36\|NZ_CP013850\|CRISPRCasFinder	2471132-2471167	36	NC_012654	Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence	47852-47887	3	0.917
NZ_CP013850_7	7.8\|2471132\|36\|NZ_CP013850\|CRISPRCasFinder	2471132-2471167	36	NZ_CP031095	Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence	64272-64307	3	0.917
NZ_CP013850_7	7.26\|2471131\|37\|NZ_CP013850\|CRT	2471131-2471167	37	NC_010418	Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence	95467-95503	3	0.919
NZ_CP013850_7	7.32\|2471526\|35\|NZ_CP013850\|CRT	2471526-2471560	35	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	183038-183072	3	0.914
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	MF370964	Pseudoalteromonas phage SL20, complete genome	73852-73882	4	0.871
NZ_CP013850_4	4.4\|2024997\|35\|NZ_CP013850\|CRISPRCasFinder	2024997-2025031	35	NC_025146	Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111	79772-79806	4	0.886
NZ_CP013850_4	4.4\|2024997\|35\|NZ_CP013850\|CRISPRCasFinder	2024997-2025031	35	NC_025146	Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111	200531-200565	4	0.886
NZ_CP013850_4	4.4\|2024997\|35\|NZ_CP013850\|CRISPRCasFinder	2024997-2025031	35	NC_010418	Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence	83392-83426	4	0.886
NZ_CP013850_7	7.18\|2471787\|37\|NZ_CP013850\|CRISPRCasFinder	2471787-2471823	37	NZ_CP014218	Clostridium botulinum strain B515 plasmid pRSJ21_3, complete sequence	35971-36007	4	0.892
NZ_CP013850_7	7.26\|2471131\|37\|NZ_CP013850\|CRT	2471131-2471167	37	NZ_CP006909	Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence	193770-193806	4	0.892
NZ_CP013850_7	7.26\|2471131\|37\|NZ_CP013850\|CRT	2471131-2471167	37	NC_025146	Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111	68983-69019	4	0.892
NZ_CP013850_7	7.26\|2471131\|37\|NZ_CP013850\|CRT	2471131-2471167	37	NZ_CP031095	Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence	64272-64308	4	0.892
NZ_CP013850_7	7.26\|2471131\|37\|NZ_CP013850\|CRT	2471131-2471167	37	NC_012654	Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence	47851-47887	4	0.892
NZ_CP013850_4	4.4\|2024997\|35\|NZ_CP013850\|CRISPRCasFinder	2024997-2025031	35	NC_010418	Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence	205022-205056	5	0.857
NZ_CP013850_7	7.36\|2471786\|38\|NZ_CP013850\|CRT	2471786-2471823	38	NZ_CP014218	Clostridium botulinum strain B515 plasmid pRSJ21_3, complete sequence	35970-36007	5	0.868
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP019203	Salmonella enterica subsp. enterica serovar Infantis strain CFSAN003307 plasmid pCFSAN003307, complete sequence	91929-91959	6	0.806
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP021835	Klebsiella pneumoniae strain AR_0120 plasmid tig00000516_pilon, complete sequence	113065-113095	6	0.806
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	MT374857	Yersinia phage vB_YpM_46, complete genome	9235-9265	6	0.806
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	AF063097	Bacteriophage P2, complete genome	9259-9289	6	0.806
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NC_049390	Escherichia virus P2_4A7b genome assembly, chromosome: 1	9257-9287	6	0.806
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NC_049386	Escherichia virus P2_2H1 genome assembly, chromosome: 1	9319-9349	6	0.806
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NC_001895	Enterobacteria phage P2, complete genome	9259-9289	6	0.806
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NC_049387	Escherichia virus P2_4B2 genome assembly, chromosome: 1	9259-9289	6	0.806
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	MT374855	Yersinia phage vB_YpM_22, complete genome	13377-13407	6	0.806
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	AY251033	Bacteriophage L-413C, complete genome	9261-9291	6	0.806
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NC_004745	Yersinia phage L-413C, complete genome	9261-9291	6	0.806
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NC_049388	Escherichia virus P2_4C9 genome assembly, chromosome: 1	9242-9272	6	0.806
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NC_049385	Escherichia virus P2_2H4 genome assembly, chromosome: 1	9283-9313	6	0.806
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	KF322032	Enterobacteria phage fiAA91-ss, complete genome	9261-9291	6	0.806
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NC_028943	Escherichia phage pro483, complete genome	16390-16420	6	0.806
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	MT374858	Yersinia phage vB_YpM_50, complete genome	13241-13271	6	0.806
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP025141	Klebsiella pneumoniae strain KP1768 plasmid KP1768_p1, complete sequence	21129-21159	6	0.806
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP025144	Klebsiella pneumoniae strain NR5632 plasmid NR5632_p1, complete sequence	20981-21011	6	0.806
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP025147	Klebsiella pneumoniae strain KP1766 plasmid KP1766_p1, complete sequence	26433-26463	6	0.806
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP018956	Escherichia coli strain Ecol_316 plasmid pEC316_KPC, complete sequence	7803-7833	6	0.806
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NC_028896	Escherichia phage pro147, complete genome	13074-13104	6	0.806
NZ_CP013850_4	4.4\|2024997\|35\|NZ_CP013850\|CRISPRCasFinder	2024997-2025031	35	NZ_CP013710	Clostridium botulinum strain F634 plasmid pRSJ2_3, complete sequence	29200-29234	6	0.829
NZ_CP013850_4	4.4\|2024997\|35\|NZ_CP013850\|CRISPRCasFinder	2024997-2025031	35	NZ_CP014152	Clostridium botulinum strain BrDura plasmid pRSJ20_1, complete sequence	9075-9109	6	0.829
NZ_CP013850_4	4.4\|2024997\|35\|NZ_CP013850\|CRISPRCasFinder	2024997-2025031	35	NC_010418	Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence	169943-169977	6	0.829
NZ_CP013850_4	4.4\|2024997\|35\|NZ_CP013850\|CRISPRCasFinder	2024997-2025031	35	NC_012654	Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence	146329-146363	6	0.829
NZ_CP013850_4	4.4\|2024997\|35\|NZ_CP013850\|CRISPRCasFinder	2024997-2025031	35	NZ_CP031095	Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence	235820-235854	6	0.829
NZ_CP013850_4	4.4\|2024997\|35\|NZ_CP013850\|CRISPRCasFinder	2024997-2025031	35	NC_010379	Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence	37038-37072	6	0.829
NZ_CP013850_4	4.4\|2024997\|35\|NZ_CP013850\|CRISPRCasFinder	2024997-2025031	35	NZ_CP013684	Clostridium botulinum strain AM282 plasmid pRSJ10_1, complete sequence	88444-88478	7	0.8
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	MK907239	Escherichia phage vB_EcoM-12474V, complete genome	24407-24437	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	MK907238	Escherichia phage vB_EcoM-12474IV, complete genome	24428-24458	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	MK907237	Escherichia phage vB_EcoM-12474III, complete genome	29212-29242	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	MK907236	Escherichia phage vB_EcoM-12474II, complete genome	24407-24437	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP039115	Piscirickettsia salmonis strain Psal-135 plasmid unnamed3, complete sequence	37084-37114	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP039063	Piscirickettsia salmonis strain Psal-099 plasmid unnamed3, complete sequence	36978-37008	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP013976	Piscirickettsia salmonis strain CGR02 plasmid pPSCRG02-1, complete sequence	70590-70620	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP013788	Piscirickettsia salmonis strain PM58386B plasmid p2PS7, complete sequence	23367-23397	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP039110	Piscirickettsia salmonis strain Psal-134 plasmid unnamed3, complete sequence	37059-37089	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP039084	Piscirickettsia salmonis strain Psal-110 plasmid unnamed3, complete sequence	35257-35287	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP039047	Piscirickettsia salmonis strain Psal-073 plasmid unnamed1, complete sequence	39620-39650	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP038902	Piscirickettsia salmonis strain Psal-006b plasmid unnamed4, complete sequence	37083-37113	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP013808	Piscirickettsia salmonis strain PM31429B plasmid p2PS12, complete sequence	23367-23397	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP048061	Piscirickettsia salmonis strain Ps-8942B plasmid Ps8942B-p5, complete sequence	63449-63479	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP013783	Piscirickettsia salmonis strain PM49811B plasmid p2PS6, complete sequence	23367-23397	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NC_028982	Bacillus phage JL, complete genome	63592-63622	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP039090	Piscirickettsia salmonis strain Psal-111 plasmid unnamed3, complete sequence	36006-36036	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP038906	Piscirickettsia salmonis strain Psal-008 plasmid unnamed2, complete sequence	12040-12070	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP038929	Piscirickettsia salmonis strain Psal-013 plasmid unnamed2, complete sequence	12040-12070	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP039174	Piscirickettsia salmonis strain Psal-138 plasmid unnamed3, complete sequence	36007-36037	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP012510	Piscirickettsia salmonis strain PM32597B1 plasmid pPSB1-2, complete sequence	1601-1631	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP013823	Piscirickettsia salmonis strain PM25344B plasmid p2PS14, complete sequence	1601-1631	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP013803	Piscirickettsia salmonis strain PM22180B plasmid p2PS13, complete sequence	1601-1631	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP011852	Piscirickettsia salmonis LF-89 = ATCC VR-1361 plasmid pPSLF89-3, complete sequence	30205-30235	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP039073	Piscirickettsia salmonis strain Psal-108 plasmid unnamed3, complete sequence	12040-12070	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP039100	Piscirickettsia salmonis strain Psal-117 plasmid unnamed3, complete sequence	12040-12070	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP039105	Piscirickettsia salmonis strain Psal-118 plasmid unnamed3, complete sequence	12040-12070	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP039179	Piscirickettsia salmonis strain Psal-139 plasmid unnamed3, complete sequence	36006-36036	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP039053	Piscirickettsia salmonis strain Psal-081 plasmid unnamed3, complete sequence	35312-35342	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP013948	Piscirickettsia salmonis strain PSCGR01 plasmid pPsCRG01-3, complete sequence	36924-36954	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP039058	Piscirickettsia salmonis strain Psal-098 plasmid unnamed3, complete sequence	12040-12070	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP039079	Piscirickettsia salmonis strain Psal-109 plasmid unnamed3, complete sequence	12040-12070	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP038921	Piscirickettsia salmonis strain Psal-010b plasmid unnamed3, complete sequence	12040-12070	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP048054	Piscirickettsia salmonis strain Ps-11091B plasmid Ps11091B-p2, complete sequence	12046-12076	8	0.742
NZ_CP013850_4	4.1\|2024944\|31\|NZ_CP013850\|PILER-CR	2024944-2024974	31	NZ_CP048054	Piscirickettsia salmonis strain Ps-11091B plasmid Ps11091B-p2, complete sequence	63020-63050	8	0.742
NZ_CP013850_4	4.4\|2024997\|35\|NZ_CP013850\|CRISPRCasFinder	2024997-2025031	35	NZ_CP013700	Clostridium botulinum strain AM1195 plasmid pRSJ11_1, complete sequence	168896-168930	8	0.771
NZ_CP013850_4	4.4\|2024997\|35\|NZ_CP013850\|CRISPRCasFinder	2024997-2025031	35	NC_025146	Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111	249579-249613	8	0.771
NZ_CP013850_7	7.16\|2471655\|36\|NZ_CP013850\|CRISPRCasFinder	2471655-2471690	36	NZ_CP053952	Bacillus cereus strain FDAARGOS_798 plasmid unnamed1, complete sequence	268987-269022	8	0.778
NZ_CP013850_7	7.16\|2471655\|36\|NZ_CP013850\|CRISPRCasFinder	2471655-2471690	36	NZ_CP053949	Bacillus cereus strain FDAARGOS_799 plasmid unnamed1, complete sequence	399137-399172	8	0.778
NZ_CP013850_7	7.5\|2470935\|35\|NZ_CP013850\|CRISPRCasFinder	2470935-2470969	35	NZ_CP009118	Borreliella valaisiana Tom4006 plasmid cp26, complete sequence	1590-1624	9	0.743
NZ_CP013850_7	7.5\|2470935\|35\|NZ_CP013850\|CRISPRCasFinder	2470935-2470969	35	NZ_CP009060	Borreliella afzelii K78 plasmid cp26, complete sequence	21023-21057	9	0.743
NZ_CP013850_7	7.5\|2470935\|35\|NZ_CP013850\|CRISPRCasFinder	2470935-2470969	35	NZ_CP018750	Borreliella garinii strain CIP 103362 isolate 20047 plasmid cp26, complete sequence	25177-25211	9	0.743
NZ_CP013850_7	7.5\|2470935\|35\|NZ_CP013850\|CRISPRCasFinder	2470935-2470969	35	NC_017725	Borreliella garinii BgVir plasmid cp26, complete sequence	21556-21590	9	0.743
NZ_CP013850_7	7.5\|2470935\|35\|NZ_CP013850\|CRISPRCasFinder	2470935-2470969	35	NC_006128	Borreliella bavariensis PBi plasmid cp26, complete sequence	21581-21615	9	0.743
NZ_CP013850_7	7.5\|2470935\|35\|NZ_CP013850\|CRISPRCasFinder	2470935-2470969	35	NZ_CP028867	Borreliella garinii strain 20047 plasmid cp26, complete sequence	598-632	9	0.743
NZ_CP013850_7	7.11\|2471331\|36\|NZ_CP013850\|CRISPRCasFinder	2471331-2471366	36	NZ_CP013615	Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence	45620-45655	9	0.75
NZ_CP013850_7	7.16\|2471655\|36\|NZ_CP013850\|CRISPRCasFinder	2471655-2471690	36	NZ_CP040783	Bacillus thuringiensis strain HM-311 plasmid p1, complete sequence	110440-110475	9	0.75
NZ_CP013850_7	7.16\|2471655\|36\|NZ_CP013850\|CRISPRCasFinder	2471655-2471690	36	NZ_CP050184	Bacillus thuringiensis strain HER1410 plasmid pLUSID1, complete sequence	269382-269417	9	0.75
NZ_CP013850_7	7.34\|2471654\|37\|NZ_CP013850\|CRT	2471654-2471690	37	NZ_CP053952	Bacillus cereus strain FDAARGOS_798 plasmid unnamed1, complete sequence	268987-269023	9	0.757
NZ_CP013850_7	7.34\|2471654\|37\|NZ_CP013850\|CRT	2471654-2471690	37	NZ_CP053949	Bacillus cereus strain FDAARGOS_799 plasmid unnamed1, complete sequence	399137-399173	9	0.757
NZ_CP013850_7	7.29\|2471330\|37\|NZ_CP013850\|CRT	2471330-2471366	37	NZ_CP013615	Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence	45619-45655	10	0.73
NZ_CP013850_7	7.34\|2471654\|37\|NZ_CP013850\|CRT	2471654-2471690	37	NZ_CP040783	Bacillus thuringiensis strain HM-311 plasmid p1, complete sequence	110440-110476	10	0.73
NZ_CP013850_7	7.34\|2471654\|37\|NZ_CP013850\|CRT	2471654-2471690	37	NZ_CP050184	Bacillus thuringiensis strain HER1410 plasmid pLUSID1, complete sequence	269381-269417	10	0.73
NZ_CP013850_6	6.1\|2417770\|40\|NZ_CP013850\|CRISPRCasFinder	2417770-2417809	40	NC_018689	Bacillus thuringiensis MC28 plasmid pMC429, complete sequence	417214-417253	11	0.725

1. spacer 4.2|2025028|21|NZ_CP013850|PILER-CR matches to NZ_CP006909 (Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence) position: , mismatch: 0, identity: 1.0

ttcctggatctaatttttgta	CRISPR spacer
ttcctggatctaatttttgta	Protospacer
*********************

2. spacer 4.2|2025028|21|NZ_CP013850|PILER-CR matches to NZ_CP013700 (Clostridium botulinum strain AM1195 plasmid pRSJ11_1, complete sequence) position: , mismatch: 0, identity: 1.0

ttcctggatctaatttttgta	CRISPR spacer
ttcctggatctaatttttgta	Protospacer
*********************

3. spacer 7.18|2471787|37|NZ_CP013850|CRISPRCasFinder matches to NZ_CP014173 (Clostridium botulinum strain B609 plasmid pRSJ22_2, complete sequence) position: , mismatch: 0, identity: 1.0

tgatatcgaggtgataagcaatggcgaataatgaatc	CRISPR spacer
tgatatcgaggtgataagcaatggcgaataatgaatc	Protospacer
*************************************

4. spacer 4.2|2025028|21|NZ_CP013850|PILER-CR matches to NZ_CP013700 (Clostridium botulinum strain AM1195 plasmid pRSJ11_1, complete sequence) position: , mismatch: 1, identity: 0.952

ttcctggatctaatttttgta	CRISPR spacer
ttcctggatctaatttttgga	Protospacer
******************* *

5. spacer 4.2|2025028|21|NZ_CP013850|PILER-CR matches to NZ_CP013684 (Clostridium botulinum strain AM282 plasmid pRSJ10_1, complete sequence) position: , mismatch: 1, identity: 0.952

ttcctggatctaatttttgta	CRISPR spacer
ttcctggatctaatatttgta	Protospacer
************** ******

6. spacer 4.2|2025028|21|NZ_CP013850|PILER-CR matches to NC_025146 (Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111) position: , mismatch: 1, identity: 0.952

ttcctggatctaatttttgta	CRISPR spacer
ttcctggatctaatttttgga	Protospacer
******************* *

7. spacer 4.2|2025028|21|NZ_CP013850|PILER-CR matches to NC_010418 (Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence) position: , mismatch: 1, identity: 0.952

ttcctggatctaatttttgta	CRISPR spacer
ttcctggatctaatatttgta	Protospacer
************** ******

8. spacer 7.8|2471132|36|NZ_CP013850|CRISPRCasFinder matches to NZ_CP014152 (Clostridium botulinum strain BrDura plasmid pRSJ20_1, complete sequence) position: , mismatch: 1, identity: 0.972

tgttcaaagtagaaaagtttatattaatagattaaa	CRISPR spacer
tgttcaaagcagaaaagtttatattaatagattaaa	Protospacer
*********.**************************

9. spacer 7.8|2471132|36|NZ_CP013850|CRISPRCasFinder matches to NZ_CP006909 (Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence) position: , mismatch: 1, identity: 0.972

tgttcaaagtagaaaagtttatattaatagattaaa	CRISPR spacer
tgttcaaagcagaaaagtttatattaatagattaaa	Protospacer
*********.**************************

10. spacer 7.8|2471132|36|NZ_CP013850|CRISPRCasFinder matches to NZ_CP013684 (Clostridium botulinum strain AM282 plasmid pRSJ10_1, complete sequence) position: , mismatch: 1, identity: 0.972

tgttcaaagtagaaaagtttatattaatagattaaa	CRISPR spacer
tgttcaaagcagaaaagtttatattaatagattaaa	Protospacer
*********.**************************

11. spacer 7.8|2471132|36|NZ_CP013850|CRISPRCasFinder matches to NZ_CP013710 (Clostridium botulinum strain F634 plasmid pRSJ2_3, complete sequence) position: , mismatch: 1, identity: 0.972

tgttcaaagtagaaaagtttatattaatagattaaa	CRISPR spacer
tgttcaaagcagaaaagtttatattaatagattaaa	Protospacer
*********.**************************

12. spacer 7.8|2471132|36|NZ_CP013850|CRISPRCasFinder matches to NC_010379 (Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence) position: , mismatch: 1, identity: 0.972

tgttcaaagtagaaaagtttatattaatagattaaa	CRISPR spacer
tgttcaaagcagaaaagtttatattaatagattaaa	Protospacer
*********.**************************

13. spacer 7.15|2471591|34|NZ_CP013850|CRISPRCasFinder matches to NZ_CP031100 (Clostridium botulinum strain CFSAN034202 plasmid p1_CFSAN034202, complete sequence) position: , mismatch: 1, identity: 0.971

gatacagagtttagggaacgttataaggcttcag	CRISPR spacer
gatacagagtttagagaacgttataaggcttcag	Protospacer
**************.*******************

14. spacer 7.15|2471591|34|NZ_CP013850|CRISPRCasFinder matches to NZ_CP014173 (Clostridium botulinum strain B609 plasmid pRSJ22_2, complete sequence) position: , mismatch: 1, identity: 0.971

gatacagagtttagggaacgttataaggcttcag	CRISPR spacer
gatacagagtttagagaacgttataaggcttcag	Protospacer
**************.*******************

15. spacer 7.33|2471590|35|NZ_CP013850|CRT matches to NZ_CP031100 (Clostridium botulinum strain CFSAN034202 plasmid p1_CFSAN034202, complete sequence) position: , mismatch: 1, identity: 0.971

tgatacagagtttagggaacgttataaggcttcag	CRISPR spacer
tgatacagagtttagagaacgttataaggcttcag	Protospacer
***************.*******************

16. spacer 7.33|2471590|35|NZ_CP013850|CRT matches to NZ_CP014173 (Clostridium botulinum strain B609 plasmid pRSJ22_2, complete sequence) position: , mismatch: 1, identity: 0.971

tgatacagagtttagggaacgttataaggcttcag	CRISPR spacer
tgatacagagtttagagaacgttataaggcttcag	Protospacer
***************.*******************

17. spacer 7.36|2471786|38|NZ_CP013850|CRT matches to NZ_CP014173 (Clostridium botulinum strain B609 plasmid pRSJ22_2, complete sequence) position: , mismatch: 1, identity: 0.974

ttgatatcgaggtgataagcaatggcgaataatgaatc	CRISPR spacer
atgatatcgaggtgataagcaatggcgaataatgaatc	Protospacer
 *************************************

18. spacer 4.4|2024997|35|NZ_CP013850|CRISPRCasFinder matches to NZ_CP013700 (Clostridium botulinum strain AM1195 plasmid pRSJ11_1, complete sequence) position: , mismatch: 2, identity: 0.943

taataatttcattcctggatctaatttttgtatta	CRISPR spacer
taattatttcattcctggatctaatttttgtattg	Protospacer
**** *****************************.

19. spacer 4.4|2024997|35|NZ_CP013850|CRISPRCasFinder matches to NZ_CP013710 (Clostridium botulinum strain F634 plasmid pRSJ2_3, complete sequence) position: , mismatch: 2, identity: 0.943

taataatttcattcctggatctaatttttgtatta	CRISPR spacer
taataatttcattcctggatataatttttgaatta	Protospacer
******************** ********* ****

20. spacer 4.4|2024997|35|NZ_CP013850|CRISPRCasFinder matches to NZ_CP014152 (Clostridium botulinum strain BrDura plasmid pRSJ20_1, complete sequence) position: , mismatch: 2, identity: 0.943

taataatttcattcctggatctaatttttgtatta	CRISPR spacer
taataatttcattcctggatataatttttgaatta	Protospacer
******************** ********* ****

21. spacer 7.8|2471132|36|NZ_CP013850|CRISPRCasFinder matches to NC_010418 (Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence) position: , mismatch: 2, identity: 0.944

tgttcaaagtagaaaagtttatattaatagattaaa	CRISPR spacer
cgttcaaagcagaaaagtttatattaatagattaaa	Protospacer
.********.**************************

22. spacer 7.14|2471527|34|NZ_CP013850|CRISPRCasFinder matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 2, identity: 0.941

ttagttttagaagctcataataatataagaccat	CRISPR spacer
ttagttttagaagctcataacaatataaaaccat	Protospacer
********************.*******.*****

23. spacer 7.26|2471131|37|NZ_CP013850|CRT matches to NZ_CP014152 (Clostridium botulinum strain BrDura plasmid pRSJ20_1, complete sequence) position: , mismatch: 2, identity: 0.946

ctgttcaaagtagaaaagtttatattaatagattaaa	CRISPR spacer
atgttcaaagcagaaaagtttatattaatagattaaa	Protospacer
 *********.**************************

24. spacer 7.26|2471131|37|NZ_CP013850|CRT matches to NZ_CP006909 (Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence) position: , mismatch: 2, identity: 0.946

ctgttcaaagtagaaaagtttatattaatagattaaa	CRISPR spacer
atgttcaaagcagaaaagtttatattaatagattaaa	Protospacer
 *********.**************************

25. spacer 7.26|2471131|37|NZ_CP013850|CRT matches to NZ_CP013684 (Clostridium botulinum strain AM282 plasmid pRSJ10_1, complete sequence) position: , mismatch: 2, identity: 0.946

ctgttcaaagtagaaaagtttatattaatagattaaa	CRISPR spacer
atgttcaaagcagaaaagtttatattaatagattaaa	Protospacer
 *********.**************************

26. spacer 7.26|2471131|37|NZ_CP013850|CRT matches to NZ_CP013710 (Clostridium botulinum strain F634 plasmid pRSJ2_3, complete sequence) position: , mismatch: 2, identity: 0.946

ctgttcaaagtagaaaagtttatattaatagattaaa	CRISPR spacer
atgttcaaagcagaaaagtttatattaatagattaaa	Protospacer
 *********.**************************

27. spacer 7.26|2471131|37|NZ_CP013850|CRT matches to NC_010379 (Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence) position: , mismatch: 2, identity: 0.946

ctgttcaaagtagaaaagtttatattaatagattaaa	CRISPR spacer
atgttcaaagcagaaaagtttatattaatagattaaa	Protospacer
 *********.**************************

28. spacer 4.4|2024997|35|NZ_CP013850|CRISPRCasFinder matches to NZ_CP006909 (Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence) position: , mismatch: 3, identity: 0.914

taataatttcattcctggatctaatttttgtatta	CRISPR spacer
cattaatttcattcctggatctaatttttgtattg	Protospacer
.* *******************************.

29. spacer 4.4|2024997|35|NZ_CP013850|CRISPRCasFinder matches to NC_010418 (Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence) position: , mismatch: 3, identity: 0.914

taataatttc-attcctggatctaatttttgtatta	CRISPR spacer
-aataatttcaattcctggatcttattcttgtatta	Protospacer
 ********* ************ ***.********

30. spacer 4.4|2024997|35|NZ_CP013850|CRISPRCasFinder matches to NC_010379 (Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence) position: , mismatch: 3, identity: 0.914

taataatttc-attcctggatctaatttttgtatta	CRISPR spacer
-aataatttcaattcctggatcttattcttgtatta	Protospacer
 ********* ************ ***.********

31. spacer 7.8|2471132|36|NZ_CP013850|CRISPRCasFinder matches to NZ_CP006909 (Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence) position: , mismatch: 3, identity: 0.917

tgttcaaagtagaaaagtttatattaatagattaaa	CRISPR spacer
tgttcaaagcagaaaagtttatattaatagactaga	Protospacer
*********.*********************.**.*

32. spacer 7.8|2471132|36|NZ_CP013850|CRISPRCasFinder matches to NC_025146 (Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111) position: , mismatch: 3, identity: 0.917

tgttcaaagtagaaaagtttatattaatagattaaa	CRISPR spacer
tattcaaagcaaaaaagtttatattaatagattaaa	Protospacer
*.*******.*.************************

33. spacer 7.8|2471132|36|NZ_CP013850|CRISPRCasFinder matches to NC_012654 (Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence) position: , mismatch: 3, identity: 0.917

tgttcaaagtagaaaagtttatattaatagattaaa	CRISPR spacer
tgttcaaagcagaaaagtttatattaatagactaga	Protospacer
*********.*********************.**.*

34. spacer 7.8|2471132|36|NZ_CP013850|CRISPRCasFinder matches to NZ_CP031095 (Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence) position: , mismatch: 3, identity: 0.917

tgttcaaagtagaaaagtttatattaatagattaaa	CRISPR spacer
tgttcaaagcagaaaagtttatattaatagactaga	Protospacer
*********.*********************.**.*

35. spacer 7.26|2471131|37|NZ_CP013850|CRT matches to NC_010418 (Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence) position: , mismatch: 3, identity: 0.919

ctgttcaaagtagaaaagtttatattaatagattaaa	CRISPR spacer
acgttcaaagcagaaaagtttatattaatagattaaa	Protospacer
 .********.**************************

36. spacer 7.32|2471526|35|NZ_CP013850|CRT matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 3, identity: 0.914

tttagttttagaagctcataataatataagaccat	CRISPR spacer
attagttttagaagctcataacaatataaaaccat	Protospacer
 ********************.*******.*****

37. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to MF370964 (Pseudoalteromonas phage SL20, complete genome) position: , mismatch: 4, identity: 0.871

-catataatcaattttcttacccttttcagta	CRISPR spacer
acttatgat-aatattcttacccttttcagta	Protospacer
 * ***.** *** ******************

38. spacer 4.4|2024997|35|NZ_CP013850|CRISPRCasFinder matches to NC_025146 (Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111) position: , mismatch: 4, identity: 0.886

taataatttcattcctggatctaatttttgtatta	CRISPR spacer
caataattttattcctggatctaatttttggattg	Protospacer
.********.******************** ***.

39. spacer 4.4|2024997|35|NZ_CP013850|CRISPRCasFinder matches to NC_025146 (Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111) position: , mismatch: 4, identity: 0.886

taataatttcattcctggatctaatttttgtatta	CRISPR spacer
taataatttcattcctggatataatttttgaagtc	Protospacer
******************** ********* * *

40. spacer 4.4|2024997|35|NZ_CP013850|CRISPRCasFinder matches to NC_010418 (Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence) position: , mismatch: 4, identity: 0.886

taataatttcattcctggatctaatttttgtatta	CRISPR spacer
catttatttcattcctggatctaatatttgtatta	Protospacer
.* * ******************** *********

41. spacer 7.18|2471787|37|NZ_CP013850|CRISPRCasFinder matches to NZ_CP014218 (Clostridium botulinum strain B515 plasmid pRSJ21_3, complete sequence) position: , mismatch: 4, identity: 0.892

tgatatcgaggtgataagcaatggcgaataatgaatc	CRISPR spacer
tgatatcgaggtgataagcaatggcgaataatttaga	Protospacer
********************************  *

42. spacer 7.26|2471131|37|NZ_CP013850|CRT matches to NZ_CP006909 (Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence) position: , mismatch: 4, identity: 0.892

ctgttcaaagtagaaaagtttatattaatagattaaa	CRISPR spacer
atgttcaaagcagaaaagtttatattaatagactaga	Protospacer
 *********.*********************.**.*

43. spacer 7.26|2471131|37|NZ_CP013850|CRT matches to NC_025146 (Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111) position: , mismatch: 4, identity: 0.892

ctgttcaaagtagaaaagtttatattaatagattaaa	CRISPR spacer
atattcaaagcaaaaaagtttatattaatagattaaa	Protospacer
 *.*******.*.************************

44. spacer 7.26|2471131|37|NZ_CP013850|CRT matches to NZ_CP031095 (Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence) position: , mismatch: 4, identity: 0.892

ctgttcaaagtagaaaagtttatattaatagattaaa	CRISPR spacer
atgttcaaagcagaaaagtttatattaatagactaga	Protospacer
 *********.*********************.**.*

45. spacer 7.26|2471131|37|NZ_CP013850|CRT matches to NC_012654 (Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence) position: , mismatch: 4, identity: 0.892

ctgttcaaagtagaaaagtttatattaatagattaaa	CRISPR spacer
atgttcaaagcagaaaagtttatattaatagactaga	Protospacer
 *********.*********************.**.*

46. spacer 4.4|2024997|35|NZ_CP013850|CRISPRCasFinder matches to NC_010418 (Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence) position: , mismatch: 5, identity: 0.857

taataatttcattcctggatctaatttttgtatta	CRISPR spacer
taataatttcattcctggatataatctttggactg	Protospacer
******************** ****.**** *.*.

47. spacer 7.36|2471786|38|NZ_CP013850|CRT matches to NZ_CP014218 (Clostridium botulinum strain B515 plasmid pRSJ21_3, complete sequence) position: , mismatch: 5, identity: 0.868

ttgatatcgaggtgataagcaatggcgaataatgaatc	CRISPR spacer
atgatatcgaggtgataagcaatggcgaataatttaga	Protospacer
 ********************************  *

48. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP019203 (Salmonella enterica subsp. enterica serovar Infantis strain CFSAN003307 plasmid pCFSAN003307, complete sequence) position: , mismatch: 6, identity: 0.806

catataatcaattttcttacc--cttttcagta	CRISPR spacer
cggataatcaattttcttaccgtctttccgg--	Protospacer
*. ******************  ****.*.*

49. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP021835 (Klebsiella pneumoniae strain AR_0120 plasmid tig00000516_pilon, complete sequence) position: , mismatch: 6, identity: 0.806

catataatcaattttcttacc--cttttcagta	CRISPR spacer
cggataatcaattttcttaccgtctttccgg--	Protospacer
*. ******************  ****.*.*

50. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to MT374857 (Yersinia phage vB_YpM_46, complete genome) position: , mismatch: 6, identity: 0.806

catataatcaattttcttacc--cttttcagta	CRISPR spacer
cggataatcaattttcttaccgtctttccgg--	Protospacer
*. ******************  ****.*.*

51. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to AF063097 (Bacteriophage P2, complete genome) position: , mismatch: 6, identity: 0.806

catataatcaattttcttacc--cttttcagta	CRISPR spacer
cggataatcaattttcttaccgtctttccgg--	Protospacer
*. ******************  ****.*.*

52. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NC_049390 (Escherichia virus P2_4A7b genome assembly, chromosome: 1) position: , mismatch: 6, identity: 0.806

catataatcaattttcttacc--cttttcagta	CRISPR spacer
cggataatcaattttcttaccgtctttccgg--	Protospacer
*. ******************  ****.*.*

53. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NC_049386 (Escherichia virus P2_2H1 genome assembly, chromosome: 1) position: , mismatch: 6, identity: 0.806

catataatcaattttcttacc--cttttcagta	CRISPR spacer
cggataatcaattttcttaccgtctttccgg--	Protospacer
*. ******************  ****.*.*

54. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NC_001895 (Enterobacteria phage P2, complete genome) position: , mismatch: 6, identity: 0.806

catataatcaattttcttacc--cttttcagta	CRISPR spacer
cggataatcaattttcttaccgtctttccgg--	Protospacer
*. ******************  ****.*.*

55. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NC_049387 (Escherichia virus P2_4B2 genome assembly, chromosome: 1) position: , mismatch: 6, identity: 0.806

catataatcaattttcttacc--cttttcagta	CRISPR spacer
cggataatcaattttcttaccgtctttccgg--	Protospacer
*. ******************  ****.*.*

56. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to MT374855 (Yersinia phage vB_YpM_22, complete genome) position: , mismatch: 6, identity: 0.806

catataatcaattttcttacc--cttttcagta	CRISPR spacer
cggataatcaattttcttaccgtctttccgg--	Protospacer
*. ******************  ****.*.*

57. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to AY251033 (Bacteriophage L-413C, complete genome) position: , mismatch: 6, identity: 0.806

catataatcaattttcttacc--cttttcagta	CRISPR spacer
cggataatcaattttcttaccgtctttccgg--	Protospacer
*. ******************  ****.*.*

58. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NC_004745 (Yersinia phage L-413C, complete genome) position: , mismatch: 6, identity: 0.806

catataatcaattttcttacc--cttttcagta	CRISPR spacer
cggataatcaattttcttaccgtctttccgg--	Protospacer
*. ******************  ****.*.*

59. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NC_049388 (Escherichia virus P2_4C9 genome assembly, chromosome: 1) position: , mismatch: 6, identity: 0.806

catataatcaattttcttacc--cttttcagta	CRISPR spacer
cggataatcaattttcttaccgtctttccgg--	Protospacer
*. ******************  ****.*.*

60. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NC_049385 (Escherichia virus P2_2H4 genome assembly, chromosome: 1) position: , mismatch: 6, identity: 0.806

catataatcaattttcttacc--cttttcagta	CRISPR spacer
cggataatcaattttcttaccgtctttccgg--	Protospacer
*. ******************  ****.*.*

61. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to KF322032 (Enterobacteria phage fiAA91-ss, complete genome) position: , mismatch: 6, identity: 0.806

catataatcaattttcttacc--cttttcagta	CRISPR spacer
cggataatcaattttcttaccgtctttccgg--	Protospacer
*. ******************  ****.*.*

62. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NC_028943 (Escherichia phage pro483, complete genome) position: , mismatch: 6, identity: 0.806

catataatcaattttcttacc--cttttcagta	CRISPR spacer
cggataatcaattttcttaccgtctttccgg--	Protospacer
*. ******************  ****.*.*

63. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to MT374858 (Yersinia phage vB_YpM_50, complete genome) position: , mismatch: 6, identity: 0.806

catataatcaattttcttacc--cttttcagta	CRISPR spacer
cggataatcaattttcttaccgtctttccgg--	Protospacer
*. ******************  ****.*.*

64. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP025141 (Klebsiella pneumoniae strain KP1768 plasmid KP1768_p1, complete sequence) position: , mismatch: 6, identity: 0.806

catataatcaattttcttacc--cttttcagta	CRISPR spacer
cggataatcaattttcttaccgtctttccgg--	Protospacer
*. ******************  ****.*.*

65. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP025144 (Klebsiella pneumoniae strain NR5632 plasmid NR5632_p1, complete sequence) position: , mismatch: 6, identity: 0.806

catataatcaattttcttacc--cttttcagta	CRISPR spacer
cggataatcaattttcttaccgtctttccgg--	Protospacer
*. ******************  ****.*.*

66. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP025147 (Klebsiella pneumoniae strain KP1766 plasmid KP1766_p1, complete sequence) position: , mismatch: 6, identity: 0.806

catataatcaattttcttacc--cttttcagta	CRISPR spacer
cggataatcaattttcttaccgtctttccgg--	Protospacer
*. ******************  ****.*.*

67. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP018956 (Escherichia coli strain Ecol_316 plasmid pEC316_KPC, complete sequence) position: , mismatch: 6, identity: 0.806

catataatcaattttcttacc--cttttcagta	CRISPR spacer
cggataatcaattttcttaccgtctttccgg--	Protospacer
*. ******************  ****.*.*

68. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NC_028896 (Escherichia phage pro147, complete genome) position: , mismatch: 6, identity: 0.806

catataatcaattttcttacc--cttttcagta	CRISPR spacer
cggataatcaattttcttaccgtctttccgg--	Protospacer
*. ******************  ****.*.*

69. spacer 4.4|2024997|35|NZ_CP013850|CRISPRCasFinder matches to NZ_CP013710 (Clostridium botulinum strain F634 plasmid pRSJ2_3, complete sequence) position: , mismatch: 6, identity: 0.829

taata-atttcattcctggatctaatttttgtatta	CRISPR spacer
-aatatatttcattcctggatctactatttgaaaga	Protospacer
 **** ****************** * **** *  *

70. spacer 4.4|2024997|35|NZ_CP013850|CRISPRCasFinder matches to NZ_CP014152 (Clostridium botulinum strain BrDura plasmid pRSJ20_1, complete sequence) position: , mismatch: 6, identity: 0.829

taata-atttcattcctggatctaatttttgtatta	CRISPR spacer
-aatatatttcattcctggatctactatttgaaaga	Protospacer
 **** ****************** * **** *  *

71. spacer 4.4|2024997|35|NZ_CP013850|CRISPRCasFinder matches to NC_010418 (Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence) position: , mismatch: 6, identity: 0.829

taata-atttcattcctggatctaatttttgtatta	CRISPR spacer
-aatatatttcattcctggatctactatttgaaaga	Protospacer
 **** ****************** * **** *  *

72. spacer 4.4|2024997|35|NZ_CP013850|CRISPRCasFinder matches to NC_012654 (Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence) position: , mismatch: 6, identity: 0.829

taata-atttcattcctggatctaatttttgtatta	CRISPR spacer
-aatatatttcattcctggatctactatttgaaaga	Protospacer
 **** ****************** * **** *  *

73. spacer 4.4|2024997|35|NZ_CP013850|CRISPRCasFinder matches to NZ_CP031095 (Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence) position: , mismatch: 6, identity: 0.829

taata-atttcattcctggatctaatttttgtatta	CRISPR spacer
-aatatatttcattcctggatctactatttgaaaga	Protospacer
 **** ****************** * **** *  *

74. spacer 4.4|2024997|35|NZ_CP013850|CRISPRCasFinder matches to NC_010379 (Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence) position: , mismatch: 6, identity: 0.829

taata-atttcattcctggatctaatttttgtatta	CRISPR spacer
-aatatatttcattcctggatctactatttgaaaga	Protospacer
 **** ****************** * **** *  *

75. spacer 4.4|2024997|35|NZ_CP013850|CRISPRCasFinder matches to NZ_CP013684 (Clostridium botulinum strain AM282 plasmid pRSJ10_1, complete sequence) position: , mismatch: 7, identity: 0.8

taataatttcattcctggatctaatttttgtatta	CRISPR spacer
ctttcatttcatttctggatctaatttttgaattg	Protospacer
.  * ********.**************** ***.

76. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to MK907239 (Escherichia phage vB_EcoM-12474V, complete genome) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta	CRISPR spacer
cggataatcaattttcttaccgtttttccgg	Protospacer
*. ****************** ****.   .

77. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to MK907238 (Escherichia phage vB_EcoM-12474IV, complete genome) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta	CRISPR spacer
cggataatcaattttcttaccgtttttccgg	Protospacer
*. ****************** ****.   .

78. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to MK907237 (Escherichia phage vB_EcoM-12474III, complete genome) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta	CRISPR spacer
cggataatcaattttcttaccgtttttccgg	Protospacer
*. ****************** ****.   .

79. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to MK907236 (Escherichia phage vB_EcoM-12474II, complete genome) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta	CRISPR spacer
cggataatcaattttcttaccgtttttccgg	Protospacer
*. ****************** ****.   .

80. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP039115 (Piscirickettsia salmonis strain Psal-135 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

81. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP039063 (Piscirickettsia salmonis strain Psal-099 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

82. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP013976 (Piscirickettsia salmonis strain CGR02 plasmid pPSCRG02-1, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

83. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP013788 (Piscirickettsia salmonis strain PM58386B plasmid p2PS7, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

84. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP039110 (Piscirickettsia salmonis strain Psal-134 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

85. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP039084 (Piscirickettsia salmonis strain Psal-110 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

86. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP039047 (Piscirickettsia salmonis strain Psal-073 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

87. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP038902 (Piscirickettsia salmonis strain Psal-006b plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

88. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP013808 (Piscirickettsia salmonis strain PM31429B plasmid p2PS12, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

89. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP048061 (Piscirickettsia salmonis strain Ps-8942B plasmid Ps8942B-p5, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

90. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP013783 (Piscirickettsia salmonis strain PM49811B plasmid p2PS6, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

91. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NC_028982 (Bacillus phage JL, complete genome) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta	CRISPR spacer
aacacctacaatttccttaccctttttagta	Protospacer
 *.*.   ******.***********.****

92. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP039090 (Piscirickettsia salmonis strain Psal-111 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

93. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP038906 (Piscirickettsia salmonis strain Psal-008 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

94. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP038929 (Piscirickettsia salmonis strain Psal-013 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

95. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP039174 (Piscirickettsia salmonis strain Psal-138 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

96. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP012510 (Piscirickettsia salmonis strain PM32597B1 plasmid pPSB1-2, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

97. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP013823 (Piscirickettsia salmonis strain PM25344B plasmid p2PS14, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

98. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP013803 (Piscirickettsia salmonis strain PM22180B plasmid p2PS13, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

99. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP011852 (Piscirickettsia salmonis LF-89 = ATCC VR-1361 plasmid pPSLF89-3, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

100. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP039073 (Piscirickettsia salmonis strain Psal-108 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

101. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP039100 (Piscirickettsia salmonis strain Psal-117 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

102. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP039105 (Piscirickettsia salmonis strain Psal-118 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

103. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP039179 (Piscirickettsia salmonis strain Psal-139 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

104. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP039053 (Piscirickettsia salmonis strain Psal-081 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

105. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP013948 (Piscirickettsia salmonis strain PSCGR01 plasmid pPsCRG01-3, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

106. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP039058 (Piscirickettsia salmonis strain Psal-098 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

107. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP039079 (Piscirickettsia salmonis strain Psal-109 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

108. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP038921 (Piscirickettsia salmonis strain Psal-010b plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

109. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP048054 (Piscirickettsia salmonis strain Ps-11091B plasmid Ps11091B-p2, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

110. spacer 4.1|2024944|31|NZ_CP013850|PILER-CR matches to NZ_CP048054 (Piscirickettsia salmonis strain Ps-11091B plasmid Ps11091B-p2, complete sequence) position: , mismatch: 8, identity: 0.742

catataatcaattttcttacccttttcagta-	CRISPR spacer
ttaatcatcaattttgttaccctttt-gctac	Protospacer
.  ** ********* ********** . **

111. spacer 4.4|2024997|35|NZ_CP013850|CRISPRCasFinder matches to NZ_CP013700 (Clostridium botulinum strain AM1195 plasmid pRSJ11_1, complete sequence) position: , mismatch: 8, identity: 0.771

taataatttcattcctggatctaatttttgtatta	CRISPR spacer
ccttcatttcattcctggatttaatttttgaaaga	Protospacer
.  * ***************.********* *  *

112. spacer 4.4|2024997|35|NZ_CP013850|CRISPRCasFinder matches to NC_025146 (Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111) position: , mismatch: 8, identity: 0.771

taataatttcattcctggatctaatttttgtatta	CRISPR spacer
ccttcatttcattcctggatttaatttttgaaaga	Protospacer
.  * ***************.********* *  *

113. spacer 7.16|2471655|36|NZ_CP013850|CRISPRCasFinder matches to NZ_CP053952 (Bacillus cereus strain FDAARGOS_798 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.778

tgattatgattctaaaaaacagattaaaagctatat	CRISPR spacer
aaattaaaattctaaaaaacagattaaaaaccacct	Protospacer
 .**** .*********************.*.*. *

114. spacer 7.16|2471655|36|NZ_CP013850|CRISPRCasFinder matches to NZ_CP053949 (Bacillus cereus strain FDAARGOS_799 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.778

tgattatgattctaaaaaacagattaaaagctatat	CRISPR spacer
aaattaaaattctaaaaaacagattaaaaaccacct	Protospacer
 .**** .*********************.*.*. *

115. spacer 7.5|2470935|35|NZ_CP013850|CRISPRCasFinder matches to NZ_CP009118 (Borreliella valaisiana Tom4006 plasmid cp26, complete sequence) position: , mismatch: 9, identity: 0.743

caagagatacaagctagaaaattggttcttataaa	CRISPR spacer
aagcttattaaagctagaaaatttgttattataaa	Protospacer
 *.   **  ************* *** *******

116. spacer 7.5|2470935|35|NZ_CP013850|CRISPRCasFinder matches to NZ_CP009060 (Borreliella afzelii K78 plasmid cp26, complete sequence) position: , mismatch: 9, identity: 0.743

caagagatacaagctagaaaattggttcttataaa	CRISPR spacer
aagcttattaaagctagaaaatttgttattataaa	Protospacer
 *.   **  ************* *** *******

117. spacer 7.5|2470935|35|NZ_CP013850|CRISPRCasFinder matches to NZ_CP018750 (Borreliella garinii strain CIP 103362 isolate 20047 plasmid cp26, complete sequence) position: , mismatch: 9, identity: 0.743

caagagatacaagctagaaaattggttcttataaa	CRISPR spacer
aagcttattaaagctagaaaatttgttattataaa	Protospacer
 *.   **  ************* *** *******

118. spacer 7.5|2470935|35|NZ_CP013850|CRISPRCasFinder matches to NC_017725 (Borreliella garinii BgVir plasmid cp26, complete sequence) position: , mismatch: 9, identity: 0.743

caagagatacaagctagaaaattggttcttataaa	CRISPR spacer
aagcttattaaagctagaaaatttgttattataaa	Protospacer
 *.   **  ************* *** *******

119. spacer 7.5|2470935|35|NZ_CP013850|CRISPRCasFinder matches to NC_006128 (Borreliella bavariensis PBi plasmid cp26, complete sequence) position: , mismatch: 9, identity: 0.743

caagagatacaagctagaaaattggttcttataaa	CRISPR spacer
aagcttattaaagctagaaaatttgttattataaa	Protospacer
 *.   **  ************* *** *******

120. spacer 7.5|2470935|35|NZ_CP013850|CRISPRCasFinder matches to NZ_CP028867 (Borreliella garinii strain 20047 plasmid cp26, complete sequence) position: , mismatch: 9, identity: 0.743

caagagatacaagctagaaaattggttcttataaa	CRISPR spacer
aagcttattaaagctagaaaatttgttattataaa	Protospacer
 *.   **  ************* *** *******

121. spacer 7.11|2471331|36|NZ_CP013850|CRISPRCasFinder matches to NZ_CP013615 (Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence) position: , mismatch: 9, identity: 0.75

tgttaaagaacttgataaatatgtaataggtcaatg	CRISPR spacer
aaaaaaagagcttgataaatatgtaatagggcagga	Protospacer
 .  *****.******************** **. .

122. spacer 7.16|2471655|36|NZ_CP013850|CRISPRCasFinder matches to NZ_CP040783 (Bacillus thuringiensis strain HM-311 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.75

tgattatgattctaaaaaacagattaaaagctatat	CRISPR spacer
aaattaaaattctaaaaaacagattaaaaaccacca	Protospacer
 .**** .*********************.*.*.

123. spacer 7.16|2471655|36|NZ_CP013850|CRISPRCasFinder matches to NZ_CP050184 (Bacillus thuringiensis strain HER1410 plasmid pLUSID1, complete sequence) position: , mismatch: 9, identity: 0.75

tgattatgattctaaaaaacagattaaaagctatat	CRISPR spacer
aaattaaaattctaaaaaacagattaaaaaccacca	Protospacer
 .**** .*********************.*.*.

124. spacer 7.34|2471654|37|NZ_CP013850|CRT matches to NZ_CP053952 (Bacillus cereus strain FDAARGOS_798 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.757

ttgattatgattctaaaaaacagattaaaagctatat	CRISPR spacer
caaattaaaattctaaaaaacagattaaaaaccacct	Protospacer
. .**** .*********************.*.*. *

125. spacer 7.34|2471654|37|NZ_CP013850|CRT matches to NZ_CP053949 (Bacillus cereus strain FDAARGOS_799 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.757

ttgattatgattctaaaaaacagattaaaagctatat	CRISPR spacer
caaattaaaattctaaaaaacagattaaaaaccacct	Protospacer
. .**** .*********************.*.*. *

126. spacer 7.29|2471330|37|NZ_CP013850|CRT matches to NZ_CP013615 (Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence) position: , mismatch: 10, identity: 0.73

ctgttaaagaacttgataaatatgtaataggtcaatg	CRISPR spacer
taaaaaaagagcttgataaatatgtaatagggcagga	Protospacer
. .  *****.******************** **. .

127. spacer 7.34|2471654|37|NZ_CP013850|CRT matches to NZ_CP040783 (Bacillus thuringiensis strain HM-311 plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.73

ttgattatgattctaaaaaacagattaaaagctatat	CRISPR spacer
caaattaaaattctaaaaaacagattaaaaaccacca	Protospacer
. .**** .*********************.*.*.

128. spacer 7.34|2471654|37|NZ_CP013850|CRT matches to NZ_CP050184 (Bacillus thuringiensis strain HER1410 plasmid pLUSID1, complete sequence) position: , mismatch: 10, identity: 0.73

ttgattatgattctaaaaaacagattaaaagctatat	CRISPR spacer
caaattaaaattctaaaaaacagattaaaaaccacca	Protospacer
. .**** .*********************.*.*.

129. spacer 6.1|2417770|40|NZ_CP013850|CRISPRCasFinder matches to NC_018689 (Bacillus thuringiensis MC28 plasmid pMC429, complete sequence) position: , mismatch: 11, identity: 0.725

ctcttagatctaaatgatg---taagtttaaatcctttaaata	CRISPR spacer
---gataacctatgtaatgaactaagtttaaatcctttaaata	Protospacer
      .*.*** .*.***   *********************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

575251 : 584667

Bacillus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024933259.1\|575251_577480_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	6.4e-106	34.0
WP_024933258.1\|578127_578337_+	recombinase RecT	H7BUU1	unidentified_phage	1.2e-14	61.9
WP_003356906.1\|579217_579565_+	hypothetical protein	A0A0A7RTL9	Clostridium_phage	1.7e-29	60.5
WP_011948235.1\|579583_579733_-	hypothetical protein	NA	NA	NA	NA
WP_011948236.1\|580250_581060_+	DUF2935 domain-containing protein	A0A2I2L551	Orpheovirus	3.0e-45	40.6
WP_011948237.1\|582018_583395_+	PhoH family protein	A0A141HS37	Bacillus_phage	3.0e-106	44.3
WP_011948238.1\|583662_584667_+	phosphodiester glycosidase family protein	A0A1P8CWN9	Bacillus_phage	4.3e-09	30.7

DBSCAN-SWA_2

920596 : 932297

Clostridium_botulinum_D_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085320476.1\|920596_922477_-	botulinum neurotoxin hemagglutinin HA70 subunit	Q786X9	Clostridium_botulinum_D_phage	7.8e-238	67.5
WP_085320477.1\|922490_922931_-	hemagglutinin	Q786Y1	Clostridium_botulinum_D_phage	3.0e-47	63.7
WP_085320478.1\|922993_923878_-	ricin-type beta-trefoil lectin domain protein	Q38196	Clostridium_botulinum_phage	2.8e-36	34.5
WP_085320479.1\|924104_924641_+	botulinum neurotoxin transcription-activating sigma factor BotR	Q38195	Clostridium_botulinum_phage	2.8e-39	52.2
WP_085320605.1\|924802_928396_+	non-toxic nonhemagglutinin NTNH	Q332E1	Clostridium_botulinum_C_phage	0.0e+00	69.1
WP_085320480.1\|928421_932297_+	botulinum neurotoxin type B	Q332E0	Clostridium_botulinum_C_phage	7.8e-184	33.1

DBSCAN-SWA_3

1612423 : 1689442

110

Clostridium_phage(47.73%)

portal,tRNA,capsid,terminase,head,tail,integrase,protease

attL 1609377:1609394|attR 1635100:1635117

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1609377:1609394	attL	NA	NA	NA	NA
WP_085320598.1\|1612423_1613473_-\|integrase	site-specific integrase	Q8SBN2	Clostridium_phage	2.5e-124	62.9
WP_012704567.1\|1613459_1613681_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012047595.1\|1613867_1614227_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_061334682.1\|1614673_1614874_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_085320599.1\|1614874_1615576_+	Rha family transcriptional regulator	A0A0A7RVQ9	Clostridium_phage	1.0e-41	57.0
WP_061334660.1\|1615576_1615738_+	hypothetical protein	Q8SBM7	Clostridium_phage	5.6e-12	66.7
WP_158087976.1\|1615750_1615924_+	hypothetical protein	NA	NA	NA	NA
WP_158644380.1\|1615915_1616149_-	hypothetical protein	NA	NA	NA	NA
WP_164468488.1\|1616305_1616449_+	hypothetical protein	NA	NA	NA	NA
WP_164078414.1\|1616441_1616609_+	hypothetical protein	NA	NA	NA	NA
WP_169990693.1\|1616611_1616860_+	hypothetical protein	NA	NA	NA	NA
WP_169990694.1\|1616916_1617078_+	hypothetical protein	NA	NA	NA	NA
WP_012704844.1\|1617055_1617367_+	hypothetical protein	NA	NA	NA	NA
WP_085320601.1\|1617366_1617591_+	hypothetical protein	NA	NA	NA	NA
WP_085320602.1\|1617592_1617751_+	hypothetical protein	NA	NA	NA	NA
WP_085320603.1\|1617723_1618221_+	hypothetical protein	A0A0A7S0G6	Clostridium_phage	2.0e-39	52.2
WP_085320604.1\|1618220_1618850_+	ERF family protein	A0A0F6N3I5	Staphylococcus_phage	7.5e-36	39.1
WP_021106453.1\|1618851_1619136_+	hypothetical protein	NA	NA	NA	NA
WP_101526913.1\|1619146_1620040_+	phage replisome organizer N-terminal domain-containing protein	A0A0A7RTL4	Clostridium_phage	4.3e-61	63.9
WP_169990714.1\|1620176_1620740_+	ATP-binding protein	M9Q1J4	Clostridium_phage	5.9e-40	48.1
WP_053818994.1\|1620753_1620948_+	hypothetical protein	A0A0M3ULL3	Bacillus_phage	1.7e-07	60.4
WP_085321217.1\|1621474_1621753_+	nucleotide pyrophosphohydrolase	NA	NA	NA	NA
WP_085321218.1\|1621848_1622097_+	hypothetical protein	NA	NA	NA	NA
WP_085321219.1\|1622099_1622444_+	hypothetical protein	NA	NA	NA	NA
WP_012342098.1\|1622460_1622613_+	hypothetical protein	NA	NA	NA	NA
WP_085321220.1\|1622674_1622890_+	hypothetical protein	NA	NA	NA	NA
WP_085321221.1\|1622940_1623129_+	hypothetical protein	NA	NA	NA	NA
WP_154694803.1\|1623322_1623484_+	hypothetical protein	NA	NA	NA	NA
WP_012720541.1\|1623526_1623676_+	hypothetical protein	NA	NA	NA	NA
WP_085321222.1\|1623717_1624026_+	hypothetical protein	NA	NA	NA	NA
WP_085321223.1\|1624129_1624318_+	hypothetical protein	NA	NA	NA	NA
WP_085321224.1\|1624327_1624696_+	hypothetical protein	A0A0A7RVR5	Clostridium_phage	1.7e-19	40.3
WP_021106461.1\|1624708_1624873_+	hypothetical protein	NA	NA	NA	NA
WP_085321225.1\|1624869_1625271_+	RusA family crossover junction endodeoxyribonuclease	A0A090D860	Clostridium_phage	1.3e-30	50.8
WP_085321226.1\|1625270_1625651_+	DNA-packaging protein	R4JMS5	Bacillus_phage	8.3e-14	36.6
WP_045894362.1\|1625651_1625978_+	hypothetical protein	A0A0A7RWJ7	Clostridium_phage	1.3e-18	47.6
WP_085321213.1\|1625990_1626128_+	hypothetical protein	NA	NA	NA	NA
WP_085321212.1\|1626129_1626288_+	hypothetical protein	NA	NA	NA	NA
WP_158087987.1\|1626280_1626430_+	hypothetical protein	NA	NA	NA	NA
WP_085321211.1\|1626431_1627076_+	hypothetical protein	NA	NA	NA	NA
WP_154694997.1\|1627076_1627235_+	hypothetical protein	NA	NA	NA	NA
WP_033049435.1\|1627445_1627961_+	hypothetical protein	NA	NA	NA	NA
WP_021106392.1\|1628150_1628366_+	hypothetical protein	NA	NA	NA	NA
WP_021106391.1\|1628366_1628912_+\|integrase	site-specific integrase	E2ELN7	Clostridium_phage	9.6e-56	60.1
WP_085321210.1\|1629066_1629342_+	hypothetical protein	A0A0K2CZP5	Paenibacillus_phage	3.0e-13	42.5
WP_021106389.1\|1629394_1629751_+	hypothetical protein	NA	NA	NA	NA
WP_021106388.1\|1629752_1630175_+	hypothetical protein	NA	NA	NA	NA
WP_021106387.1\|1630174_1630648_+	hypothetical protein	A0A0A7RUV1	Clostridium_phage	5.1e-13	38.2
WP_012099377.1\|1630734_1631088_+	hypothetical protein	NA	NA	NA	NA
WP_021106386.1\|1631123_1631588_+\|terminase	phage terminase small subunit P27 family	Q9ZXG2	Bacillus_phage	1.8e-50	63.1
WP_085321209.1\|1631584_1633285_+\|terminase	terminase large subunit	A6M948	Geobacillus_virus	3.8e-183	57.2
WP_021106385.1\|1633300_1634485_+\|portal	phage portal protein	A0A2K9VBP0	Staphylococcus_phage	2.5e-69	37.1
WP_021106384.1\|1634474_1635233_+\|protease	Clp protease ClpP	A0A0B5A796	Paenibacillus_phage	3.2e-73	61.1
1635100:1635117	attR	NA	NA	NA	NA
WP_021106383.1\|1635225_1636353_+\|capsid	phage major capsid protein	A0A1B1P7R4	Bacillus_phage	2.1e-121	62.4
WP_033049432.1\|1636372_1636528_+	termination factor Rho	NA	NA	NA	NA
WP_021106381.1\|1636542_1636869_+\|head,tail	phage gp6-like head-tail connector protein	Q8SBP7	Clostridium_phage	1.1e-14	50.0
WP_021106380.1\|1636849_1637176_+\|head	phage head closure protein	NA	NA	NA	NA
WP_021106379.1\|1637168_1637552_+	HK97 gp10 family phage protein	E2ELI9	Clostridium_phage	5.4e-29	50.7
WP_021106378.1\|1637548_1637887_+	hypothetical protein	A0A0S2SY15	Bacillus_phage	1.4e-17	43.7
WP_021106377.1\|1637893_1638475_+\|tail	phage major tail protein, phi13 family	E2ELJ1	Clostridium_phage	1.1e-60	60.1
WP_033049430.1\|1638504_1638792_+	hypothetical protein	E2ELJ2	Clostridium_phage	3.0e-16	49.5
WP_085321208.1\|1639060_1644394_+\|tail	phage tail tape measure protein	A0A0H4TEZ5	Erysipelothrix_phage	6.1e-62	48.6
WP_085321207.1\|1644410_1645277_+\|tail	phage tail family protein	E2ELJ6	Clostridium_phage	5.7e-111	70.2
WP_085321206.1\|1645328_1646348_+	hypothetical protein	E2ELJ7	Clostridium_phage	8.2e-117	60.5
WP_012704076.1\|1647707_1648013_+	hypothetical protein	J9QEB9	Clostridium_phage	5.6e-05	37.0
WP_085321180.1\|1648028_1648214_+	hypothetical protein	A0A2H4JGH3	uncultured_Caudovirales_phage	7.8e-10	67.4
WP_021106368.1\|1648425_1649478_+	hypothetical protein	NA	NA	NA	NA
WP_021106367.1\|1649502_1649859_+	hypothetical protein	NA	NA	NA	NA
WP_021106366.1\|1649975_1650365_+	hypothetical protein	NA	NA	NA	NA
WP_021106365.1\|1650434_1650689_+	hemolysin XhlA family protein	A0A0A7RTX0	Clostridium_phage	1.4e-25	69.6
WP_021106364.1\|1650704_1650899_+	hypothetical protein	NA	NA	NA	NA
WP_080443933.1\|1650938_1651973_+	peptidoglycan-binding protein	Q0SPG7	Clostridium_phage	5.3e-39	44.7
WP_047404577.1\|1652404_1652596_+	hypothetical protein	A0A0A7RTH9	Clostridium_phage	3.5e-13	70.9
WP_085321179.1\|1652580_1652826_+	hypothetical protein	NA	NA	NA	NA
WP_085321178.1\|1653001_1653895_+	hypothetical protein	NA	NA	NA	NA
WP_085321177.1\|1654055_1654253_-	helix-turn-helix transcriptional regulator	A0A2H4J358	uncultured_Caudovirales_phage	3.4e-11	63.1
WP_011986860.1\|1655135_1655912_+	shikimate dehydrogenase	NA	NA	NA	NA
WP_003386380.1\|1655913_1656966_+	type IV pilus twitching motility protein PilT	NA	NA	NA	NA
WP_003386378.1\|1657043_1657187_-	hypothetical protein	NA	NA	NA	NA
WP_003386376.1\|1657624_1658899_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_012047886.1\|1659055_1660309_+	cell division protein FtsA	NA	NA	NA	NA
WP_003386373.1\|1660331_1661441_+	cell division protein FtsZ	NA	NA	NA	NA
WP_011986857.1\|1661753_1662551_+	sigma-E processing peptidase SpoIIGA	NA	NA	NA	NA
WP_003399432.1\|1662562_1663270_+	RNA polymerase sporulation sigma factor SigE	A0A2H4JC68	uncultured_Caudovirales_phage	2.5e-19	44.3
WP_011986856.1\|1663344_1664118_+	RNA polymerase sporulation sigma factor SigG	A0A0A0RV91	Bacillus_phage	1.1e-44	40.2
WP_004440893.1\|1664264_1664528_+	YlmC/YmxH family sporulation protein	NA	NA	NA	NA
WP_003399430.1\|1664658_1665114_+	transcriptional repressor NrdR	NA	NA	NA	NA
WP_045540430.1\|1665562_1666282_+	peptidoglycan editing factor PgeF	NA	NA	NA	NA
WP_011986854.1\|1666292_1666991_+	response regulator transcription factor	W8CYM9	Bacillus_phage	3.0e-46	44.4
WP_011986853.1\|1667002_1668712_+	HAMP domain-containing protein	W8CYF6	Bacillus_phage	3.7e-37	39.1
WP_011986852.1\|1668958_1669831_+	phosphate ABC transporter substrate-binding protein	E3SM63	Prochlorococcus_phage	5.9e-07	29.8
WP_003394571.1\|1670038_1670962_+	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
WP_003404697.1\|1670961_1671846_+	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_011986851.1\|1671858_1672608_+	phosphate ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.0e-15	33.1
WP_080443554.1\|1672637_1673291_+	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_061312343.1\|1673742_1675077_+	DUF512 domain-containing protein	NA	NA	NA	NA
WP_011986848.1\|1675079_1676399_+	ribosome biogenesis GTPase Der	NA	NA	NA	NA
WP_085321176.1\|1676569_1677568_+	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_061320718.1\|1677590_1677776_-	hypothetical protein	NA	NA	NA	NA
WP_011986845.1\|1678165_1679647_+	stage IV sporulation protein A	NA	NA	NA	NA
WP_075143182.1\|1680374_1680569_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003402184.1\|1681086_1682088_+	asparaginase	NA	NA	NA	NA
WP_003388628.1\|1682281_1683160_+	YicC family protein	NA	NA	NA	NA
WP_003388626.1\|1683175_1683451_+	DUF370 domain-containing protein	NA	NA	NA	NA
WP_003388624.1\|1683450_1684080_+	guanylate kinase	U5TH34	Cowpox_virus	1.7e-16	31.3
WP_003388622.1\|1684060_1684279_+	DNA-directed RNA polymerase subunit omega	NA	NA	NA	NA
WP_012047883.1\|1684280_1685468_+	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	2.8e-44	34.1
WP_011986843.1\|1685805_1688013_+	primosomal protein N'	NA	NA	NA	NA
WP_003388617.1\|1688040_1688484_+	peptide deformylase	E3SLL2	Synechococcus_phage	7.2e-17	44.9
WP_045540425.1\|1688476_1689442_+\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	5.4e-09	35.2

DBSCAN-SWA_4

1848278 : 1895665

Clostridium_phage(60.0%)

holin,integrase,capsid,tail,portal

attL 1865349:1865366|attR 1890187:1890204

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085320911.1\|1848278_1849901_-	recombinase family protein	A0A1L2BY67	Clostridium_phage	5.7e-88	35.5
WP_085320910.1\|1849995_1851357_-	DUF4041 domain-containing protein	X5JAC1	Clostridium_phage	1.1e-68	57.4
WP_053530369.1\|1851500_1851935_-	ImmA/IrrE family metallo-endopeptidase	D6R412	Bacillus_phage	1.3e-26	48.6
WP_003392456.1\|1851981_1852443_-	helix-turn-helix transcriptional regulator	A0A0A8WE28	Clostridium_phage	1.3e-16	55.7
WP_053530370.1\|1852620_1852854_+	helix-turn-helix domain-containing protein	A0A0B5A7F0	Streptococcus_phage	1.9e-05	42.6
WP_085320909.1\|1852911_1853769_+	phage antirepressor KilAC domain-containing protein	A0A0A7S0G2	Clostridium_phage	5.2e-72	53.7
WP_085320908.1\|1853933_1854179_-	hypothetical protein	NA	NA	NA	NA
WP_169990695.1\|1854247_1854457_+	hypothetical protein	NA	NA	NA	NA
WP_139815813.1\|1854477_1854630_+	Com family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_169990696.1\|1854682_1854841_+	hypothetical protein	NA	NA	NA	NA
WP_169990697.1\|1854849_1854993_+	hypothetical protein	NA	NA	NA	NA
WP_085320906.1\|1855270_1855837_+	hypothetical protein	NA	NA	NA	NA
WP_085320904.1\|1855849_1856707_+	hypothetical protein	E5DV80	Deep-sea_thermophilic_phage	1.2e-57	46.7
WP_012047839.1\|1856709_1856856_+	hypothetical protein	NA	NA	NA	NA
WP_169990698.1\|1856871_1857048_+	hypothetical protein	NA	NA	NA	NA
WP_085320935.1\|1857140_1857440_+	hypothetical protein	NA	NA	NA	NA
WP_085320903.1\|1857464_1858337_+	phage replisome organizer N-terminal domain-containing protein	Q7Y4K5	Streptococcus_phage	3.1e-40	40.2
WP_085320934.1\|1858296_1859100_+	ATP-binding protein	A0A2K9V3L7	Faecalibacterium_phage	1.1e-34	35.2
WP_085320902.1\|1859119_1859353_+	hypothetical protein	NA	NA	NA	NA
WP_085320901.1\|1859364_1860264_+	hypothetical protein	NA	NA	NA	NA
WP_053530381.1\|1860265_1860574_+	hypothetical protein	NA	NA	NA	NA
WP_053530382.1\|1860576_1860819_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A0K2CZ86	Paenibacillus_phage	2.8e-15	51.9
WP_014521173.1\|1860818_1861199_+	nucleotide pyrophosphohydrolase	R4T830	Halovirus	9.5e-10	46.3
WP_039774237.1\|1861296_1861689_+	hypothetical protein	A0A0A7RUF3	Clostridium_phage	1.9e-37	62.3
WP_085320900.1\|1861715_1862429_+	hypothetical protein	A0A0A7RWW3	Clostridium_phage	4.2e-75	64.4
WP_061311389.1\|1862493_1862856_+	hypothetical protein	A0A0A7RVR5	Clostridium_phage	1.1e-20	44.1
WP_085320899.1\|1863032_1863434_+	DUF1064 domain-containing protein	NA	NA	NA	NA
WP_076045540.1\|1863436_1863784_+	hypothetical protein	A0A0A7RTL9	Clostridium_phage	1.1e-28	57.9
WP_085320898.1\|1863822_1864515_+	hypothetical protein	Q6JII4	Burkholderia_virus	3.0e-30	32.0
WP_061293690.1\|1864563_1864944_+	hypothetical protein	NA	NA	NA	NA
WP_085320897.1\|1864970_1865330_+	hypothetical protein	NA	NA	NA	NA
1865349:1865366	attL	NA	NA	NA	NA
WP_021134668.1\|1865360_1865540_+	hypothetical protein	NA	NA	NA	NA
WP_158087982.1\|1865557_1865725_+	hypothetical protein	A0A0A7RUF8	Clostridium_phage	1.9e-18	89.1
WP_085320896.1\|1865802_1866798_+\|integrase	tyrosine-type recombinase/integrase	B6SCW8	Bacteriophage	1.2e-06	25.3
WP_085320895.1\|1866814_1867030_+	hypothetical protein	NA	NA	NA	NA
WP_085320894.1\|1867127_1867331_+	hypothetical protein	NA	NA	NA	NA
WP_085320933.1\|1867323_1867848_+	hypothetical protein	A0A0A7RVX8	Clostridium_phage	2.5e-37	52.9
WP_101526914.1\|1867971_1868733_+	hypothetical protein	A0A0A7RTW7	Clostridium_phage	2.4e-81	62.2
WP_085320892.1\|1868766_1869930_+	ImmA/IrrE family metallo-endopeptidase	A0A0A7RTT7	Clostridium_phage	1.8e-176	79.6
WP_021106405.1\|1870153_1870363_+	hypothetical protein	NA	NA	NA	NA
WP_085320891.1\|1870423_1870948_+	hypothetical protein	NA	NA	NA	NA
WP_085320890.1\|1871003_1871696_+	hypothetical protein	A0A0A8WFS6	Clostridium_phage	5.7e-45	52.1
WP_085320889.1\|1871688_1873146_+	DEAD/DEAH box helicase family protein	C9E2I7	Enterococcus_phage	6.1e-166	63.8
WP_085320888.1\|1873145_1874621_+\|portal	phage portal protein	A0A0A7RW62	Clostridium_phage	6.6e-176	63.2
WP_085320887.1\|1876346_1876646_+	hypothetical protein	NA	NA	NA	NA
WP_085320886.1\|1876693_1877311_+	phage scaffold protein	A0A0A7RW68	Clostridium_phage	1.9e-71	69.1
WP_085320885.1\|1877324_1877681_+	hypothetical protein	A0A2H4J872	uncultured_Caudovirales_phage	7.2e-44	77.1
WP_085320884.1\|1877701_1878736_+\|capsid	major capsid protein	A0A1J1GG50	Clostridium_phage	2.6e-118	63.7
WP_085320883.1\|1878787_1878988_+	hypothetical protein	A0A0A7RTZ2	Clostridium_phage	4.3e-06	48.2
WP_085320882.1\|1878990_1879299_+	hypothetical protein	A0A2H4J040	uncultured_Caudovirales_phage	1.4e-32	64.1
WP_085320881.1\|1879295_1879658_+	hypothetical protein	NA	NA	NA	NA
WP_085320880.1\|1879654_1880029_+	hypothetical protein	E7DNB1	Pneumococcus_phage	2.0e-12	31.1
WP_053530409.1\|1880370_1880997_+	hypothetical protein	E7DNB3	Pneumococcus_phage	6.5e-40	48.4
WP_085320879.1\|1881052_1881469_+	hypothetical protein	NA	NA	NA	NA
WP_101526915.1\|1881446_1881638_+	hypothetical protein	A0A0A8WHP4	Clostridium_phage	3.5e-05	50.0
WP_085320877.1\|1881713_1882346_+	hypothetical protein	NA	NA	NA	NA
WP_085320876.1\|1882421_1888310_+\|tail	phage tail tape measure protein	A0A2H4JDX3	uncultured_Caudovirales_phage	3.8e-41	29.7
WP_085320875.1\|1888323_1889193_+\|tail	phage tail family protein	E2ELJ6	Clostridium_phage	5.6e-82	54.1
WP_085320874.1\|1889196_1890291_+	hypothetical protein	E2ELJ7	Clostridium_phage	1.4e-93	48.6
1890187:1890204	attR	NA	NA	NA	NA
WP_093510978.1\|1890290_1892261_+	hypothetical protein	E2ELJ8	Clostridium_phage	7.5e-66	45.4
WP_085320873.1\|1892277_1892643_+	hypothetical protein	NA	NA	NA	NA
WP_003357857.1\|1892635_1892758_+	XkdX family protein	A0A0A7S0E7	Clostridium_phage	4.5e-06	57.5
WP_085320872.1\|1892880_1893297_+\|holin	phage holin family protein	M9Q253	Clostridium_phage	2.5e-35	56.6
WP_085320871.1\|1893337_1894363_+	peptidoglycan-binding protein	Q0SPG7	Clostridium_phage	1.3e-40	41.2
WP_085320870.1\|1894588_1895665_+	DUF2075 domain-containing protein	A0A1V0SET7	Hokovirus	2.4e-18	25.9

DBSCAN-SWA_5

2435459 : 2512268

Clostridium_phage(68.63%)

plate,coat,holin,integrase,tRNA,capsid,terminase,head,tail,portal

attL 2434393:2434410|attR 2516941:2516958

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2434393:2434410	attL	NA	NA	NA	NA
WP_061309457.1\|2435459_2436095_+\|coat	SafA/ExsA family spore coat assembly protein	A0A0E3JT82	Bacillus_phage	2.5e-39	45.1
WP_061309456.1\|2436238_2437198_-	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_061309455.1\|2437228_2437384_-	hypothetical protein	NA	NA	NA	NA
WP_085320769.1\|2437646_2438180_+	amidase domain-containing protein	NA	NA	NA	NA
WP_061309453.1\|2438290_2439265_-	hypothetical protein	NA	NA	NA	NA
WP_033045787.1\|2439416_2439572_-	hypothetical protein	NA	NA	NA	NA
WP_014520731.1\|2441881_2442445_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_011986313.1\|2444130_2444571_+	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
WP_085320768.1\|2444718_2445372_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_011986311.1\|2445642_2446593_-	DUF1002 domain-containing protein	NA	NA	NA	NA
WP_011986310.1\|2446887_2447475_+	3'-5' exonuclease	NA	NA	NA	NA
WP_085320767.1\|2447715_2449398_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	9.4e-17	30.9
WP_085320766.1\|2449428_2450250_-	ABC transporter permease	NA	NA	NA	NA
WP_085320765.1\|2450253_2451228_-	ABC transporter permease	NA	NA	NA	NA
WP_085320764.1\|2451241_2452837_-	diguanylate phosphodiesterase	NA	NA	NA	NA
WP_085320763.1\|2452973_2453498_-	TraR/DksA C4-type zinc finger protein	NA	NA	NA	NA
WP_085320761.1\|2454123_2454528_+\|tRNA	tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO	NA	NA	NA	NA
WP_085320760.1\|2454583_2457817_-	SNF2 helicase associated domain-containing protein	A0A1B1ISM1	uncultured_Mediterranean_phage	4.1e-29	27.3
WP_003358943.1\|2458176_2458728_+	hypothetical protein	NA	NA	NA	NA
WP_085320759.1\|2458880_2459894_-	WG repeat-containing protein	NA	NA	NA	NA
WP_076178048.1\|2460924_2461809_+	SDR family oxidoreductase	A0A2N9QUX2	Trichoplusia_ni_ascovirus	1.4e-51	42.1
WP_025776446.1\|2462024_2462858_-	DUF975 family protein	NA	NA	NA	NA
WP_003385957.1\|2463097_2464438_-	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	2.7e-35	29.8
WP_085320758.1\|2464525_2465998_-	CZB domain-containing protein	NA	NA	NA	NA
WP_085320757.1\|2466423_2467593_-	alanine racemase	A0A0P0YM39	Yellowstone_lake_mimivirus	1.9e-29	29.2
WP_012344341.1\|2468030_2468585_-	hemerythrin domain-containing protein	NA	NA	NA	NA
WP_085320756.1\|2468617_2469238_-	hypothetical protein	NA	NA	NA	NA
WP_085320755.1\|2469470_2469638_-	transcriptional regulator	Q8SBM7	Clostridium_phage	1.4e-10	58.5
WP_085320754.1\|2469775_2470021_-	hypothetical protein	NA	NA	NA	NA
WP_012721426.1\|2470005_2470200_-	hypothetical protein	A0A0A7RTH9	Clostridium_phage	9.1e-17	82.1
WP_085320753.1\|2472068_2472839_-	N-acetylmuramoyl-L-alanine amidase	A0A2H4J8A3	uncultured_Caudovirales_phage	2.3e-87	65.2
WP_085320752.1\|2472883_2473303_-\|holin	phage holin family protein	A0A0A7S099	Clostridium_phage	3.4e-45	67.6
WP_085320751.1\|2473393_2473609_-	hypothetical protein	A0A2H4JGH3	uncultured_Caudovirales_phage	1.0e-08	67.4
WP_012704076.1\|2473624_2473930_-	hypothetical protein	J9QEB9	Clostridium_phage	5.6e-05	37.0
WP_085321034.1\|2475193_2475820_-	DUF2313 domain-containing protein	A0A0A7RVP9	Clostridium_phage	3.0e-85	74.6
WP_085321035.1\|2475800_2476895_-\|plate	baseplate J/gp47 family protein	A0A0A7S096	Clostridium_phage	8.4e-160	76.1
WP_085321036.1\|2476895_2477303_-	DUF2634 domain-containing protein	A0A0A7RTH1	Clostridium_phage	8.2e-52	80.8
WP_085321037.1\|2477306_2477651_-	DUF2577 domain-containing protein	A0A0A7RTJ2	Clostridium_phage	2.0e-38	73.7
WP_085321038.1\|2477653_2478628_-	hypothetical protein	A0A0A7RTZ4	Clostridium_phage	8.6e-156	83.6
WP_085321039.1\|2478639_2479317_-	LysM peptidoglycan-binding domain-containing protein	A0A0A7RVP5	Clostridium_phage	7.9e-92	74.6
WP_085321040.1\|2479316_2481476_-	hypothetical protein	A0A0A7S091	Clostridium_phage	5.4e-134	53.0
WP_085321041.1\|2481561_2482140_-	hypothetical protein	A0A0A7RTT9	Clostridium_phage	6.0e-56	56.6
WP_014521323.1\|2482380_2482794_-	hypothetical protein	A0A0A7RTN3	Clostridium_phage	1.1e-51	74.8
WP_085321042.1\|2482809_2483274_-\|tail	phage tail tube protein	A0A0A7RVP1	Clostridium_phage	1.1e-68	81.8
WP_085321043.1\|2483277_2484588_-\|tail	phage tail sheath subtilisin-like domain-containing protein	A0A0A7S087	Clostridium_phage	3.7e-210	84.9
WP_169990700.1\|2484589_2484760_-	hypothetical protein	A0A0A7RTV4	Clostridium_phage	1.0e-11	69.2
WP_169990718.1\|2484749_2485181_-	hypothetical protein	A0A0A7RTI2	Clostridium_phage	5.4e-54	78.5
WP_162832543.1\|2485189_2485354_-	hypothetical protein	NA	NA	NA	NA
WP_085321045.1\|2485367_2485802_-	HK97 gp10 family phage protein	A0A0A7RTT0	Clostridium_phage	5.8e-64	82.2
WP_085321046.1\|2485801_2486185_-	hypothetical protein	A0A0A7S083	Clostridium_phage	7.2e-50	80.3
WP_085321047.1\|2486186_2486531_-\|head,tail	phage head-tail connector protein	A0A0A7RTX9	Clostridium_phage	1.8e-44	77.2
WP_085321048.1\|2486549_2487617_-\|coat	phage coat protein	A0A0A7RTH8	Clostridium_phage	3.8e-181	89.0
WP_085321049.1\|2487639_2488203_-	scaffolding protein	A0A0A7RTM5	Clostridium_phage	3.0e-20	41.1
WP_085321050.1\|2488326_2488590_-	hypothetical protein	A0A0S2MYE7	Enterococcus_phage	7.4e-30	69.8
WP_085321051.1\|2488607_2488910_-	hypothetical protein	NA	NA	NA	NA
WP_085321052.1\|2488970_2489171_-	hypothetical protein	NA	NA	NA	NA
WP_169990719.1\|2489167_2490712_-\|capsid	minor capsid protein	A0A0A7RVN1	Clostridium_phage	1.2e-167	69.5
WP_085321054.1\|2490701_2492153_-\|portal	phage portal protein	A0A0A7S074	Clostridium_phage	3.3e-236	88.2
WP_085321055.1\|2492165_2493575_-\|terminase	phage terminase large subunit	A0A0A7RTS1	Clostridium_phage	8.5e-213	87.9
WP_085321056.1\|2493567_2494155_-\|terminase	terminase small subunit	U5PZD3	Bacillus_phage	9.8e-30	43.0
WP_085296086.1\|2494377_2494929_-	hypothetical protein	S5MNT8	Brevibacillus_phage	2.7e-13	30.5
WP_085321057.1\|2494903_2495293_-	hypothetical protein	NA	NA	NA	NA
WP_085321058.1\|2495301_2496666_-	DEAD/DEAH box helicase	A0A1S7FYY5	Listeria_phage	1.3e-162	61.4
WP_012703762.1\|2496668_2496836_-	hypothetical protein	NA	NA	NA	NA
WP_085321059.1\|2496828_2497110_-	VRR-NUC domain-containing protein	A0A0A7RTE1	Clostridium_phage	2.3e-21	83.1
WP_169990720.1\|2497375_2499766_-	hypothetical protein	A0A0A7RTG3	Clostridium_phage	0.0e+00	89.2
WP_085321061.1\|2499892_2500636_+	hypothetical protein	NA	NA	NA	NA
WP_085321145.1\|2500671_2502642_-	DNA polymerase	A0A0A7RTL3	Clostridium_phage	0.0e+00	84.5
WP_085321062.1\|2502680_2503001_-	hypothetical protein	NA	NA	NA	NA
WP_093490881.1\|2503249_2503810_-	DUF2815 family protein	A0A0A7RVM4	Clostridium_phage	2.8e-95	91.4
WP_085321063.1\|2503881_2505027_-	DUF2800 domain-containing protein	A0A0A7S066	Clostridium_phage	6.1e-193	86.6
WP_085321064.1\|2505026_2505476_-	hypothetical protein	A0A0A7RTD8	Clostridium_phage	1.6e-11	51.6
WP_085321065.1\|2505509_2505764_-	hypothetical protein	A0A0A7RTF9	Clostridium_phage	9.7e-27	74.4
WP_085321066.1\|2505763_2506015_-	hypothetical protein	A0A0A7RTK9	Clostridium_phage	1.4e-25	66.7
WP_085321067.1\|2506033_2506387_-	hypothetical protein	A0A0A7RVM0	Clostridium_phage	1.6e-35	68.1
WP_085321068.1\|2506450_2507002_-	sigma-70 family RNA polymerase sigma factor	M9Q2I8	Clostridium_phage	3.5e-21	34.8
WP_169990701.1\|2507016_2507175_-	hypothetical protein	NA	NA	NA	NA
WP_085321069.1\|2508032_2508332_-	hypothetical protein	NA	NA	NA	NA
WP_085321070.1\|2508348_2508552_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_085321071.1\|2508781_2509207_+	helix-turn-helix transcriptional regulator	D2XR39	Bacillus_phage	1.7e-31	58.0
WP_021106440.1\|2509225_2509672_+	ImmA/IrrE family metallo-endopeptidase	Q0H245	Geobacillus_phage	2.9e-26	42.8
WP_085321072.1\|2509734_2510808_+\|integrase	site-specific integrase	A0A2R2ZGM9	Clostridioides_phage	4.1e-18	29.7
WP_085321073.1\|2511716_2512268_-	DUF4352 domain-containing protein	A0A0S2MVG4	Bacillus_phage	1.1e-11	32.0
2516941:2516958	attR	NA	NA	NA	NA

DBSCAN-SWA_6

2622255 : 2629321

uncultured_Caudovirales_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011986260.1\|2622255_2623212_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	7.7e-16	33.5
WP_011949102.1\|2623326_2623986_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	3.0e-59	51.2
WP_004451708.1\|2624169_2624760_-	GTP cyclohydrolase I FolE	S4U0J3	uncultured_phage	7.0e-44	52.8
WP_011949101.1\|2624763_2625429_-	putative 7-carboxy-7-deazaguanine synthase QueE	S4TZT1	uncultured_phage	1.7e-38	44.1
WP_085280233.1\|2625430_2625862_-	6-carboxytetrahydropterin synthase QueD	A0A1U9WRB3	Streptococcus_virus	1.0e-12	33.1
WP_003358645.1\|2625879_2626641_-	2-hydroxyglutaryl-CoA dehydratase	NA	NA	NA	NA
WP_061320494.1\|2626757_2627753_-	2-hydroxyacyl-CoA dehydratase	NA	NA	NA	NA
WP_011949098.1\|2628376_2629321_+	YafY family transcriptional regulator	A0A1B0RXM1	Streptococcus_phage	4.2e-14	31.6

DBSCAN-SWA_7

2736717 : 2752742

Clostridium_phage(77.78%)

plate,portal,capsid,terminase,head,tail,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085321122.1\|2736717_2737827_-\|plate	baseplate J/gp47 family protein	A0A0A7RUN3	Clostridium_phage	2.1e-41	34.3
WP_085321123.1\|2737838_2738276_-	DUF2634 domain-containing protein	NA	NA	NA	NA
WP_085321124.1\|2738287_2738605_-	DUF2577 family protein	NA	NA	NA	NA
WP_085321125.1\|2738617_2739550_-	hypothetical protein	NA	NA	NA	NA
WP_085321126.1\|2739549_2739981_-	hypothetical protein	NA	NA	NA	NA
WP_085321127.1\|2740024_2742655_-\|tail	phage tail tape measure protein	A0A0U4IIN6	Exiguobacterium_phage	1.4e-30	34.8
WP_085321128.1\|2742891_2743311_-	hypothetical protein	NA	NA	NA	NA
WP_012704978.1\|2743326_2743755_-\|tail	phage tail tube protein	NA	NA	NA	NA
WP_085321129.1\|2743765_2744851_-\|tail	phage tail sheath protein	A0A090D804	Clostridium_phage	2.6e-28	29.1
WP_085321149.1\|2745348_2745768_-	hypothetical protein	NA	NA	NA	NA
WP_085321130.1\|2745815_2746226_-	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_021106485.1\|2746227_2746437_-	hypothetical protein	NA	NA	NA	NA
WP_085321131.1\|2746446_2746782_-\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
WP_085321132.1\|2746856_2747153_-\|head,tail	phage gp6-like head-tail connector protein	A0A2H4JAK5	uncultured_Caudovirales_phage	6.4e-14	45.5
WP_085321133.1\|2747178_2748390_-\|capsid	phage major capsid protein	Q0SPK4	Clostridium_phage	6.3e-132	60.9
WP_085321134.1\|2748389_2749133_-\|protease	Clp protease ClpP	Q0SPK3	Clostridium_phage	1.4e-89	68.9
WP_085280364.1\|2749132_2750338_-\|portal	phage portal protein	Q0SPK2	Clostridium_phage	1.1e-171	73.0
WP_085321150.1\|2750556_2752275_-\|terminase	terminase large subunit	A0A0A7RVS5	Clostridium_phage	1.1e-294	86.9
WP_085321135.1\|2752289_2752742_-\|terminase	phage terminase small subunit P27 family	A0A0A7S0C4	Clostridium_phage	1.4e-63	84.0

DBSCAN-SWA_8

2762149 : 2770639

Clostridium_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_053818994.1\|2762149_2762344_-	hypothetical protein	A0A0M3ULL3	Bacillus_phage	1.7e-07	60.4
WP_169990714.1\|2762357_2762921_-	ATP-binding protein	M9Q1J4	Clostridium_phage	5.9e-40	48.1
WP_085321215.1\|2763057_2763939_-	phage replisome organizer N-terminal domain-containing protein	A0A0A7RTL4	Clostridium_phage	8.5e-62	60.8
WP_021106453.1\|2763949_2764234_-	hypothetical protein	NA	NA	NA	NA
WP_012704670.1\|2764235_2764865_-	ERF family protein	A0A0F6N3I5	Staphylococcus_phage	5.7e-36	39.1
WP_021106452.1\|2764864_2765362_-	hypothetical protein	A0A0A7S0G6	Clostridium_phage	7.5e-39	52.1
WP_021106451.1\|2765334_2765493_-	hypothetical protein	NA	NA	NA	NA
WP_021106450.1\|2765547_2765745_-	hypothetical protein	NA	NA	NA	NA
WP_021106449.1\|2765734_2765986_-	hypothetical protein	NA	NA	NA	NA
WP_021106448.1\|2766004_2766187_-	hypothetical protein	A0A0A7RTQ2	Clostridium_phage	6.7e-06	44.1
WP_021106447.1\|2766253_2766625_+	DUF2513 domain-containing protein	A0A1S5SCT1	Streptococcus_phage	1.5e-12	36.6
WP_021106446.1\|2766610_2766883_-	hypothetical protein	NA	NA	NA	NA
WP_085320607.1\|2766885_2767146_-	ubiquitin	NA	NA	NA	NA
WP_085320608.1\|2767157_2767985_-	ORF6N domain-containing protein	A0A0A7RUE5	Clostridium_phage	6.8e-69	55.9
WP_003399954.1\|2768338_2768542_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_085320609.1\|2768747_2769113_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_085320610.1\|2769124_2770639_+	recombinase family protein	A0A0A7S0M8	Clostridium_phage	4.1e-229	77.4

DBSCAN-SWA_9

2847029 : 2870229

Clostridium_phage(47.37%)

plate,terminase,capsid,tail,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085320617.1\|2847029_2847791_-	N-acetylmuramoyl-L-alanine amidase	I1TJX3	Clostridium_phage	5.0e-50	57.6
WP_043032313.1\|2847829_2848024_-	hypothetical protein	NA	NA	NA	NA
WP_085320618.1\|2848037_2848271_-	hemolysin XhlA family protein	A0A0A7S0T7	Clostridium_phage	2.0e-26	76.6
WP_085320619.1\|2848330_2848846_-	hypothetical protein	NA	NA	NA	NA
WP_085320620.1\|2848970_2849117_-	XkdX family protein	A0A0A7RTH5	Clostridium_phage	1.5e-11	66.7
WP_085320621.1\|2849116_2849314_-	D-alanyl-D-alanine carboxypeptidase	NA	NA	NA	NA
WP_085320622.1\|2849325_2851974_-	hypothetical protein	I1TJW8	Clostridium_phage	1.6e-119	33.0
WP_085320623.1\|2851973_2853338_-\|plate	BppU family phage baseplate upper protein	A0A0A7S181	Clostridium_phage	5.0e-85	78.2
WP_085320624.1\|2853353_2855036_-\|tail	phage tail protein	A0A0A7RUI9	Clostridium_phage	2.5e-78	42.8
WP_085320625.1\|2855020_2855698_-\|tail	phage tail family protein	A0A0A7RWN1	Clostridium_phage	7.3e-45	43.1
WP_085320626.1\|2855697_2858367_-\|tail	phage tail tape measure protein	A0A0H4TEZ5	Erysipelothrix_phage	1.2e-69	50.0
WP_093510968.1\|2858416_2858569_-	Com family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_085320627.1\|2858610_2859102_-	hypothetical protein	A0A0K2CP90	Brevibacillus_phage	2.5e-10	36.1
WP_085320628.1\|2859149_2859743_-	hypothetical protein	A0A0A8WHV7	Clostridium_phage	5.0e-66	61.4
WP_085320629.1\|2859742_2860087_-	AP endonuclease	A0A1J1JCF3	Escherichia_phage	7.0e-20	50.8
WP_085320630.1\|2860150_2860357_+	hypothetical protein	NA	NA	NA	NA
WP_085320631.1\|2860373_2860598_-	hypothetical protein	NA	NA	NA	NA
WP_085320632.1\|2860601_2861096_-	hypothetical protein	NA	NA	NA	NA
WP_085320633.1\|2861096_2861528_-	chloramphenicol resistance protein	A0A0A8WJ92	Clostridium_phage	3.4e-40	56.6
WP_085320634.1\|2861524_2861869_-\|capsid	capsid protein	A0A2K9V3E3	Faecalibacterium_phage	5.8e-06	36.5
WP_085320636.1\|2862280_2862547_-	hypothetical protein	NA	NA	NA	NA
WP_085320637.1\|2862633_2863605_-	hypothetical protein	A0A2P1JTX1	Anoxybacillus_phage	2.5e-54	36.4
WP_085320638.1\|2863675_2864323_-	DUF4355 domain-containing protein	A0A1V0DZW6	Clostridioides_phage	5.7e-23	36.6
WP_085320639.1\|2864419_2865142_-\|capsid	minor capsid protein	Q6SE81	Lactobacillus_prophage	1.3e-07	32.3
WP_085320640.1\|2865141_2866398_-\|portal	phage portal protein	A0A1V0DZW8	Clostridioides_phage	7.6e-80	39.9
WP_158087977.1\|2866403_2866565_-	hypothetical protein	NA	NA	NA	NA
WP_085320641.1\|2866581_2868312_-\|terminase	terminase	A0A1V0DZW7	Clostridioides_phage	6.9e-108	37.8
WP_085320642.1\|2868719_2869148_-	hypothetical protein	NA	NA	NA	NA
WP_085320643.1\|2869260_2870229_-	DUF4236 domain-containing protein	Q331S8	Clostridium_botulinum_C_phage	1.4e-09	39.3

DBSCAN-SWA_10

3214160 : 3223629

Synechococcus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003385254.1\|3214160_3215660_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	1.9e-69	46.9
WP_012047940.1\|3215873_3216491_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.5e-25	40.6
WP_012099415.1\|3216618_3217614_-	phosphoribosylformylglycinamidine cyclo-ligase	M4QRQ6	Synechococcus_phage	9.9e-67	43.7
WP_169990721.1\|3217674_3219117_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.4e-58	35.4
WP_012047943.1\|3219214_3219919_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	6.0e-42	42.1
WP_003357851.1\|3219918_3220398_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.1e-26	48.7
WP_169990708.1\|3221073_3223629_-	selenium-dependent xanthine dehydrogenase	A0A0P0IVM8	Acinetobacter_phage	1.3e-09	32.4

DBSCAN-SWA_11

3364192 : 3392285

Clostridium_phage(80.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085320716.1\|3364192_3365317_-	chorismate synthase	A0A291AU41	Pandoravirus	1.2e-31	30.3
WP_085320717.1\|3365457_3366228_-	N-acetylmuramoyl-L-alanine amidase	A0A2H4J8A3	uncultured_Caudovirales_phage	1.1e-84	62.9
WP_030036506.1\|3366374_3366569_-	hypothetical protein	NA	NA	NA	NA
WP_003358009.1\|3366587_3366842_-	hemolysin XhlA family protein	A0A0A7RTX0	Clostridium_phage	4.8e-26	70.9
WP_085320718.1\|3366994_3367804_-	cell adhesion protein	NA	NA	NA	NA
WP_085320719.1\|3367855_3368854_-	LamG domain-containing protein	A0A0A7RU14	Clostridium_phage	6.5e-50	41.7
WP_085320720.1\|3368940_3369720_-	discoidin domain-containing protein	NA	NA	NA	NA
WP_085320721.1\|3369721_3370423_-	hypothetical protein	NA	NA	NA	NA
WP_085320722.1\|3370503_3371589_-	signal peptidase II	A0A0A7RU66	Clostridium_phage	6.7e-141	69.8
WP_085320723.1\|3371600_3372599_-	hypothetical protein	A0A0A7RW91	Clostridium_phage	7.5e-139	71.1
WP_003360052.1\|3372610_3372865_-	hypothetical protein	A0A0A7S0T0	Clostridium_phage	1.1e-33	81.0
WP_085320724.1\|3372870_3374766_-	hypothetical protein	A0A0A7RU09	Clostridium_phage	2.9e-115	52.3
WP_085320725.1\|3374780_3376019_-	hypothetical protein	A0A0A7RU28	Clostridium_phage	1.5e-197	81.3
WP_085320726.1\|3376041_3377022_-	hypothetical protein	A0A0A7RU61	Clostridium_phage	6.1e-109	61.6
WP_085320727.1\|3377023_3378373_-	caspase family protein	A0A0A7RW86	Clostridium_phage	1.1e-73	73.5
WP_085320728.1\|3378387_3378729_-	hypothetical protein	A0A0A7S0S4	Clostridium_phage	2.7e-16	55.7
WP_085320729.1\|3378741_3379827_-	hypothetical protein	NA	NA	NA	NA
WP_085320730.1\|3379813_3380248_-	hypothetical protein	NA	NA	NA	NA
WP_024932986.1\|3380260_3381664_-	membrane protein	A0A0A7RU22	Clostridium_phage	1.2e-04	42.4
WP_003393374.1\|3381739_3381907_-	hypothetical protein	A0A0A7RW80	Clostridium_phage	1.1e-15	68.5
WP_012048055.1\|3381941_3382358_-	hypothetical protein	A0A0A7S0S0	Clostridium_phage	7.6e-45	70.5
WP_012048056.1\|3382373_3383261_-	hypothetical protein	A0A0A7RTZ9	Clostridium_phage	3.1e-120	75.3
WP_024932988.1\|3383265_3383685_-	hypothetical protein	A0A0A7RU17	Clostridium_phage	3.5e-58	72.7
WP_024932989.1\|3383690_3384038_-	hypothetical protein	A0A0A7RU51	Clostridium_phage	1.3e-34	61.6
WP_024932990.1\|3384042_3384408_-	hypothetical protein	A0A0A7RW73	Clostridium_phage	3.8e-32	56.2
WP_085320731.1\|3384407_3384692_-	hypothetical protein	A0A0A7S0R4	Clostridium_phage	1.7e-24	60.2
WP_003358043.1\|3385379_3385901_-	hypothetical protein	A0A0A7RVS1	Clostridium_phage	3.6e-36	50.6
WP_024932992.1\|3386014_3386335_-	hypothetical protein	NA	NA	NA	NA
WP_169929098.1\|3386391_3387192_-	ATP-binding protein	A0A2K9V3L7	Faecalibacterium_phage	2.9e-32	36.3
WP_024932994.1\|3387181_3388087_-	phage replisome organizer N-terminal domain-containing protein	A8ASN4	Listeria_phage	3.2e-40	39.1
WP_003384849.1\|3388180_3388393_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_085320732.1\|3388454_3388664_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012048067.1\|3388855_3389266_+	helix-turn-helix transcriptional regulator	A0A0A7RUJ5	Clostridium_phage	1.0e-09	56.2
WP_003403583.1\|3389567_3389717_+	hypothetical protein	NA	NA	NA	NA
WP_085320733.1\|3390797_3392285_+	MBOAT family protein	A0A125RNP0	Pseudomonas_phage	3.7e-65	38.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP013852

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 6017

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085321188.1\|794_1325_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_085321189.1\|1547_1904_-	hypothetical protein	NA	NA	NA	NA
WP_085321190.1\|1943_2588_-	histidine phosphatase family protein	NA	NA	NA	NA
WP_011988285.1\|2933_3155_+	DUF1659 domain-containing protein	NA	NA	NA	NA
WP_085321191.1\|3174_3402_+	DUF2922 domain-containing protein	NA	NA	NA	NA
WP_031942519.1\|3462_3690_-	hypothetical protein	NA	NA	NA	NA
WP_085321192.1\|3691_4177_-	DUF3990 domain-containing protein	NA	NA	NA	NA
WP_061324436.1\|4173_4401_-	DUF3791 domain-containing protein	NA	NA	NA	NA
WP_085321193.1\|4625_6017_-	replication protein	B5LPT8	Bacillus_virus	2.3e-21	26.6

DBSCAN-SWA_2

10114 : 15145

Organic_Lake_phycodnavirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085321197.1\|10114_11944_-	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	7.3e-23	28.9
WP_085321198.1\|11956_15145_-	lantibiotic dehydratase	A0A2H4PQG8	Staphylococcus_phage	1.9e-90	26.9

DBSCAN-SWA_3

18288 : 21388

Staphylococcus_phage(50.0%)

integrase

attL 11286:11302|attR 22867:22883

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
11286:11302	attL	NA	NA	NA	NA
WP_169990723.1\|18288_19032_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	1.8e-36	37.1
WP_085321204.1\|19422_20040_+	hypothetical protein	NA	NA	NA	NA
WP_085321186.1\|20812_21388_+\|integrase	site-specific integrase	A0A1B1P7Y2	Bacillus_phage	3.8e-34	44.7
22867:22883	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP013850

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP013852

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection