CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP021885	Enterococcus faecium strain WEFA23 chromosome, complete genome	1 crisprs	cas2,cas14j,csa3,cas3,DEDDh,DinG	0	0	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP021885_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP021885_1

754652-754761

Orphan

Consensus_repeat	Method
CTTTGCTCAACCAGTATTATTCATCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP021885_1

>merge|NZ_CP021885|1|754652-754761|CRISPRCasFinder
CTTTGCTCAACCAGTATTATTCATCACCTATTCACTTCGTTCATAGTGATTCTACTCGCTTTGCTCGAAAGGAAACTCCTTTCGCTTTGCTCAACCAGTATTGTTCATCA

>NZ_CP021885|1|1|754652-754761|CRISPRCasFinder
CTTTGCTCAACCAGTATTATTCATCA	CCTATTCACTTCGTTCATAGTGATTCTACTCGCTTTGCTCGAAAGGAAACTCCTTTCG
CTTTGCTCAACCAGTATTGTTCATCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021885.1\|WP_002291638.1\|755781_756204_-\|50S-ribosomal-protein-L11	unknown	unknown	gnl\|CDD\|234661
NZ_CP021885.1\|WP_002294580.1\|760346_760892_-\|transcription-termination/antitermination-protein-NusG	unknown	unknown	gnl\|CDD\|180161
NZ_CP021885.1\|WP_002294585.1\|756546_757215_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	unknown	unknown	gnl\|CDD\|224674
NZ_CP021885.1\|WP_002294587.1\|754988_755678_-\|50S-ribosomal-protein-L1	unknown	unknown	gnl\|CDD\|180071
NZ_CP021885.1\|WP_002294581.1\|759382_760270_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|283645
NZ_CP021885.1\|WP_002294588.1\|753654_754023_-\|50S-ribosomal-protein-L7/L12	unknown	unknown	gnl\|CDD\|234671
NZ_CP021885.1\|WP_002294577.1\|761500_762145_+\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341358
NZ_CP021885.1\|WP_002301342.1\|752859_753549_-\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_CP021885.1\|WP_002300319.1\|749852_751385_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_CP021885.1\|WP_101735285.1\|758190_759291_-\|lactate-oxidase	unknown	unknown	gnl\|CDD\|240088
NZ_CP021885.1\|WP_002291634.1\|754075_754579_-\|50S-ribosomal-protein-L10	unknown	unknown	gnl\|CDD\|234632
NZ_CP021885.1\|WP_002287788.1\|747949_748663_-\|MgtC/SapB-family-protein	unknown	unknown	gnl\|CDD\|224204
NZ_CP021885.1\|WP_002294584.1\|757227_758100_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	unknown	unknown	gnl\|CDD\|129801
NZ_CP021885.1\|WP_002287792.1\|745446_746412_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|275027
NZ_CP021885.1\|WP_002287787.1\|748917_749619_-\|glucosamine-6-phosphate-deaminase	unknown	unknown	gnl\|CDD\|238693
NZ_CP021885.1\|WP_002301341.1\|751575_752778_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340882
NZ_CP021885.1\|WP_002298514.1\|746500_747640_-\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NZ_CP021885.1\|WP_002287793.1\|743237_745397_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|180921
NZ_CP021885.1\|WP_002294579.1\|760992_761163_-\|preprotein-translocase-subunit-SecE	unknown	unknown	gnl\|CDD\|376355
NZ_CP021885.1\|WP_002294578.1\|761186_761339_-\|50S-ribosomal-protein-L33	unknown	unknown	gnl\|CDD\|234783

Protein	Function_ID	Function_description	E-value
NZ_CP021885.1\|WP_002291638.1\|755781_756204_-\|50S-ribosomal-protein-L11	gnl\|CDD\|234661	PRK00140, rplK, 50S ribosomal protein L11; Validated.	9.059e-96
NZ_CP021885.1\|WP_002294580.1\|760346_760892_-\|transcription-termination/antitermination-protein-NusG	gnl\|CDD\|180161	PRK05609, nusG, transcription antitermination protein NusG; Validated.	1.97252e-86
NZ_CP021885.1\|WP_002294585.1\|756546_757215_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	gnl\|CDD\|224674	COG1760, SdaA, L-serine deaminase [Amino acid transport and metabolism].	1.41351e-73
NZ_CP021885.1\|WP_002294587.1\|754988_755678_-\|50S-ribosomal-protein-L1	gnl\|CDD\|180071	PRK05424, rplA, 50S ribosomal protein L1; Validated.	1.66496e-146
NZ_CP021885.1\|WP_002294581.1\|759382_760270_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|283645	pfam06028, DUF915, Alpha/beta hydrolase of unknown function (DUF915). This family consists of several bacterial proteins of unknown function. Members of this family have an alpha/beta hydrolase fold.	4.81944e-80
NZ_CP021885.1\|WP_002294588.1\|753654_754023_-\|50S-ribosomal-protein-L7/L12	gnl\|CDD\|234671	PRK00157, rplL, 50S ribosomal protein L7/L12; Reviewed.	5.30333e-45
NZ_CP021885.1\|WP_002294577.1\|761500_762145_+\|CBS-domain-containing-protein	gnl\|CDD\|341358	cd02205, CBS_pair_SF, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains superfamily. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	5.69774e-14
NZ_CP021885.1\|WP_002301342.1\|752859_753549_-\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	4.71236e-18
NZ_CP021885.1\|WP_002300319.1\|749852_751385_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	4.70503e-170
NZ_CP021885.1\|WP_101735285.1\|758190_759291_-\|lactate-oxidase	gnl\|CDD\|240088	cd04737, LOX_like_FMN, L-Lactate oxidase (LOX) FMN-binding domain. LOX is a member of the family of FMN-containing alpha-hydroxyacid oxidases and catalyzes the oxidation of l-lactate using molecular oxygen to generate pyruvate and H2O2. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate dehydrogenase (MDH), and long chain hydroxyacid oxidase (LCHAO).	0
NZ_CP021885.1\|WP_002291634.1\|754075_754579_-\|50S-ribosomal-protein-L10	gnl\|CDD\|234632	PRK00099, rplJ, 50S ribosomal protein L10; Reviewed.	3.03735e-67
NZ_CP021885.1\|WP_002287788.1\|747949_748663_-\|MgtC/SapB-family-protein	gnl\|CDD\|224204	COG1285, SapB, Uncharacterized membrane protein [Function unknown].	6.15701e-49
NZ_CP021885.1\|WP_002294584.1\|757227_758100_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	gnl\|CDD\|129801	TIGR00718, Probable_L-serine_dehydratase_alpha_chain, L-serine dehydratase, iron-sulfur-dependent, alpha subunit. This enzyme is also called serine deaminase. L-serine dehydratase converts serine into pyruvate in the gluconeogenesis pathway from serine. This model describes the alpha chain of an iron-sulfur-dependent L-serine dehydratase, found in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of alpha chains from the homologous region of single chain forms such as found in Escherichia coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	2.63238e-103
NZ_CP021885.1\|WP_002287792.1\|745446_746412_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	gnl\|CDD\|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	0
NZ_CP021885.1\|WP_002287787.1\|748917_749619_-\|glucosamine-6-phosphate-deaminase	gnl\|CDD\|238693	cd01399, GlcN6P_deaminase, GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or deamination. It is the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate (GlcNAc6P). GlcN6P deaminase is a hexameric enzyme that is allosterically activated by GlcNAc6P.	8.8122e-119
NZ_CP021885.1\|WP_002301341.1\|751575_752778_-\|MFS-transporter	gnl\|CDD\|340882	cd17324, MFS_NepI_like, Purine ribonucleoside efflux pump NepI and similar transporters of the Major Facilitator Superfamily. This family is composed of purine efflux pumps such as Escherichia coli NepI and Bacillus subtilis PbuE, sugar efflux transporters such as Corynebacterium glutamicum arabinose efflux permease, multidrug resistance (MDR) transporters such as Streptomyces lividans chloramphenicol resistance protein (CmlR), and similar proteins. NepI and PbuE are involved in the efflux of purine ribonucleosides such as guanosine, adenosine and inosine, as well as purine bases like guanine, adenine, and hypoxanthine, and purine base analogs. They play a role in the maintenance of cellular purine base pools, as well as in protecting the cells and conferring resistance against toxic purine base analogs such as 6-mercaptopurine. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The NepI-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.62165e-69
NZ_CP021885.1\|WP_002298514.1\|746500_747640_-\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	6.95043e-62
NZ_CP021885.1\|WP_002287793.1\|743237_745397_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|180921	PRK07306, PRK07306, ribonucleotide-diphosphate reductase subunit alpha; Validated.	0
NZ_CP021885.1\|WP_002294579.1\|760992_761163_-\|preprotein-translocase-subunit-SecE	gnl\|CDD\|376355	pfam00584, SecE, SecE/Sec61-gamma subunits of protein translocation complex. SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.	1.48e-13
NZ_CP021885.1\|WP_002294578.1\|761186_761339_-\|50S-ribosomal-protein-L33	gnl\|CDD\|234783	PRK00504, rpmG, 50S ribosomal protein L33; Validated.	3.12722e-17

>NZ_CP021885.1|WP_002291634.1|754075_754579_-|50S-ribosomal-protein-L10
MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRKQLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAKEAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVADKEDGDAA
>NZ_CP021885.1|WP_002294588.1|753654_754023_-|50S-ribosomal-protein-L7/L12
MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAAGGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSKEEAEELKAKLEEVGASVTVK
>NZ_CP021885.1|WP_002301342.1|752859_753549_-|TVP38/TMEM64-family-protein
MKKKIIRLMLITLGIILILVVGYRLYLEYQTDIQLFLNPRASKAELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPFIGAGINVLGNALGNISAVFLMHRLKFLDKKTETNHWVQSIRQMKHPKIGVMLGYMIPVIPSSMVNFAADAMKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVMLVASVTVLVGLVVFIYKDRKKKQGKQKHK
>NZ_CP021885.1|WP_002301341.1|751575_752778_-|MFS-transporter
MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSVSTSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTLFACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVASLFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLREAAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADSYSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGEAASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKGKRNLENKK
>NZ_CP021885.1|WP_002300319.1|749852_751385_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKSTLIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYTKEYEKEEKIAFLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNLSGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEFLDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKYKAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRPLLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDLYWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQLTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIEPK
>NZ_CP021885.1|WP_002287787.1|748917_749619_-|glucosamine-6-phosphate-deaminase
MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYKEMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDLEAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRFFDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNHDNVVVIIDEEAASKL
>NZ_CP021885.1|WP_002287788.1|747949_748663_-|MgtC/SapB-family-protein
MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILVCMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVTKQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLEIQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVIEELSVHKNITKLHLVSIAQ
>NZ_CP021885.1|WP_002298514.1|746500_747640_-|AI-2E-family-transporter
MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAIFLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQTIQLTQSLPTYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASVSKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETLSAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIVGLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILGMLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE
>NZ_CP021885.1|WP_002287792.1|745446_746412_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta
MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDDWRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHAKSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETFLFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETLKDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTANDVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE
>NZ_CP021885.1|WP_002287793.1|743237_745397_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha
MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVKPNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKFYSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLNAGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGYEGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIRVKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNIRKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPSVINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPPIQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIARERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVMKDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETIPYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLNILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI
>NZ_CP021885.1|WP_002294587.1|754988_755678_-|50S-ribosomal-protein-L1
MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEVAYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQKIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGKVTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTFGPGIHVDQASF
>NZ_CP021885.1|WP_002291638.1|755781_756204_-|50S-ribosomal-protein-L11
MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNARTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSSDQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE
>NZ_CP021885.1|WP_002294585.1|756546_757215_+|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta
MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPDSVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSEKAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVPGMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSVNYFD
>NZ_CP021885.1|WP_002294584.1|757227_758100_+|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha
MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKNLSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVNAKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISGAEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPCVKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTPTAKRLAEEILNKRA
>NZ_CP021885.1|WP_101735285.1|758190_759291_-|lactate-oxidase
MTYHTSNEEHPIDIVNIASLEGRVKERMEAGAFGYIRGGSEDEWTMKENTTSFNSKKIMPRILRGIDSADLHTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVATAGSIFSISTYANTTIKDAADAAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKSIILTADSTLGGYREEDVINQFQFPLPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSPEDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEHVFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKNTKLMD
>NZ_CP021885.1|WP_002294581.1|759382_760270_-|alpha/beta-fold-hydrolase
MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHSMLHENQEVDQLVSRFIWKE
>NZ_CP021885.1|WP_002294580.1|760346_760892_-|transcription-termination/antitermination-protein-NusG
MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVPEEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPAPLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVNIDMFGRETSTELDFDQVDKID
>NZ_CP021885.1|WP_002294579.1|760992_761163_-|preprotein-translocase-subunit-SecE
MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMDTAIQSLFGWILK
>NZ_CP021885.1|WP_002294578.1|761186_761339_-|50S-ribosomal-protein-L33
MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYTLHKETK
>NZ_CP021885.1|WP_002294577.1|761500_762145_+|CBS-domain-containing-protein
MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSGNIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAVLDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIASCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

79267 : 88330

Synechococcus_phage(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002331832.1\|79267_79846_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.0e-26	38.8
WP_002321731.1\|79842_80886_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	2.7e-62	43.7
WP_002309482.1\|80917_82357_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.3e-53	33.1
WP_002338225.1\|82341_84564_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.1e-150	41.4
WP_002288017.1\|84564_85236_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_002338224.1\|85237_85492_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_002288021.1\|85491_86220_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	E3SPA9	Prochlorococcus_phage	4.6e-45	41.4
WP_002338223.1\|86475_86853_+	hypothetical protein	NA	NA	NA	NA
WP_002306865.1\|87034_88330_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.0e-18	33.1

DBSCAN-SWA_2

446985 : 455581

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_101735263.1\|446985_449175_+	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	1.4e-286	66.6
WP_101735264.1\|449613_450216_+	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A288TZV3	Enterococcus_phage	2.2e-53	58.0
WP_002294035.1\|450269_451391_-	DNA polymerase IV	NA	NA	NA	NA
WP_002298874.1\|451499_452372_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	4.0e-88	60.4
WP_002288076.1\|452440_452788_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	5.1e-18	41.1
WP_101735265.1\|452780_453605_-	stage 0 sporulation family protein	NA	NA	NA	NA
WP_002300512.1\|453640_454579_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	5.5e-35	34.1
WP_002292340.1\|454592_454922_-	hypothetical protein	NA	NA	NA	NA
WP_002294039.1\|454936_455581_-	dTMP kinase	M1PSC7	Streptococcus_phage	4.2e-58	52.6

DBSCAN-SWA_3

482141 : 522280

Bacillus_phage(27.27%)

bacteriocin,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002324581.1\|482141_483059_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_002338709.1\|483062_483800_-	glycerophosphodiester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	2.3e-12	40.0
WP_002289403.1\|483890_484418_-	hypothetical protein	NA	NA	NA	NA
WP_002289402.1\|484597_485191_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	8.9e-55	55.6
WP_002319637.1\|485294_485780_-	gamma carbonic anhydrase family protein	NA	NA	NA	NA
WP_002296291.1\|485931_486129_-	hypothetical protein	NA	NA	NA	NA
WP_101735267.1\|486223_487984_-	multidrug efflux ABC transporter subunit EfrB	W8CYL7	Bacillus_phage	2.9e-53	28.8
WP_002340293.1\|487980_489711_-	multidrug efflux ABC transporter subunit EfrA	W8CYL7	Bacillus_phage	7.1e-44	28.2
WP_002287947.1\|490103_490316_+	DNA-dependent RNA polymerase auxiliary subunit epsilon family protein	NA	NA	NA	NA
WP_002327197.1\|490317_491997_+	ribonuclease J	NA	NA	NA	NA
WP_002294067.1\|492250_492451_-	cold-shock protein	Q9AZD3	Lactococcus_phage	3.7e-21	71.2
WP_002294069.1\|492600_493293_-	JAB domain-containing protein	NA	NA	NA	NA
WP_002325438.1\|493347_494001_-	HAD family phosphatase	NA	NA	NA	NA
WP_002294071.1\|493990_495304_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_002298863.1\|495613_498259_-\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	1.4e-163	43.1
WP_101735268.1\|498651_499299_-	redox-sensing transcriptional repressor Rex	NA	NA	NA	NA
WP_002287955.1\|499871_501083_-\|tRNA	tRNA 4-thiouridine(8) synthase ThiI	NA	NA	NA	NA
WP_002294077.1\|501098_502241_-	cysteine desulfurase	NA	NA	NA	NA
WP_002287957.1\|502406_504128_-	septation ring formation regulator EzrA	NA	NA	NA	NA
WP_002287958.1\|504326_504887_-	haloacid dehalogenase	A0A0H3UZF4	Geobacillus_virus	2.3e-28	45.1
WP_002294078.1\|504912_505752_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_002287960.1\|505785_506619_-	DUF72 domain-containing protein	NA	NA	NA	NA
WP_002287961.1\|506850_507819_+	asparaginase	NA	NA	NA	NA
WP_002287962.1\|507973_508711_-	acyl-ACP thioesterase	NA	NA	NA	NA
WP_002287963.1\|508726_509560_-	phosphotransferase	NA	NA	NA	NA
WP_002294080.1\|509761_511090_-	aminopeptidase C	R4TV59	Phaeocystis_globosa_virus	7.3e-73	38.1
WP_002338712.1\|512179_512809_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_002298848.1\|512931_513306_-	iron-sulfur cluster biosynthesis family protein	NA	NA	NA	NA
WP_000997695.1\|513608_514787_-\|transposase	IS256-like element ISEf1 family transposase	NA	NA	NA	NA
WP_101735269.1\|514948_515215_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_025477461.1\|515224_515389_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_010733279.1\|515911_516214_+	hypothetical protein	F0PIG8	Enterococcus_phage	1.2e-07	53.3
WP_002293280.1\|516377_517337_+\|transposase	IS30-like element IS6770 family transposase	NA	NA	NA	NA
WP_002395929.1\|517773_518952_+\|transposase	IS256-like element ISEfm2 family transposase	NA	NA	NA	NA
WP_002292444.1\|519113_520544_+	hypothetical protein	NA	NA	NA	NA
WP_002329890.1\|520540_521137_-	recombinase family protein	A0A0A8WIK3	Clostridium_phage	5.7e-09	30.3
WP_101735270.1\|521153_522280_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	4.3e-74	53.7

DBSCAN-SWA_4

1302075 : 1363907

uncultured_Mediterranean_phage(28.57%)

transposase,holin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002294192.1\|1302075_1303251_-\|holin	betaine/proline/choline family ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	1.0e-17	32.9
WP_002325221.1\|1303443_1304475_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_002328048.1\|1305093_1307733_+	cation-translocating P-type ATPase	A0A1J0FA34	Only_Syngen_Nebraska_virus	1.6e-84	31.7
WP_002296566.1\|1307900_1308599_-	DUF975 family protein	NA	NA	NA	NA
WP_002294183.1\|1308816_1309962_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	2.5e-82	40.9
WP_002300794.1\|1310058_1310439_+	preprotein translocase subunit YajC	NA	NA	NA	NA
WP_002328050.1\|1310743_1313341_+	bifunctional acetaldehyde-CoA/alcohol dehydrogenase	NA	NA	NA	NA
WP_002288261.1\|1313569_1314676_+	glycosyl hydrolase	NA	NA	NA	NA
WP_010717980.1\|1314692_1315721_+	TRAP transporter substrate-binding protein	NA	NA	NA	NA
WP_002328053.1\|1315726_1316206_+	TRAP transporter small permease	NA	NA	NA	NA
WP_010717981.1\|1316221_1317511_+	5-dehydro-4-deoxy-D-glucuronate isomerase	NA	NA	NA	NA
WP_033603016.1\|1317530_1318334_+	gluconate 5-dehydrogenase	NA	NA	NA	NA
WP_002328061.1\|1318582_1319647_-	type 2 isopentenyl-diphosphate Delta-isomerase	NA	NA	NA	NA
WP_002288233.1\|1319643_1320729_-	phosphomevalonate kinase	NA	NA	NA	NA
WP_101735312.1\|1320741_1321719_-	diphosphomevalonate decarboxylase	NA	NA	NA	NA
WP_002288231.1\|1321711_1322656_-	mevalonate kinase	NA	NA	NA	NA
WP_002322895.1\|1322977_1323631_+	deoxynucleoside kinase	C1KFI3	Lactobacillus_virus	1.1e-58	52.3
WP_010717982.1\|1323715_1324621_+	magnesium transporter CorA family protein	NA	NA	NA	NA
WP_002294161.1\|1324622_1325255_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_002293357.1\|1325574_1326099_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	1.4e-14	33.3
WP_002289309.1\|1326170_1326371_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_002293355.1\|1326423_1326783_+	50S ribosomal protein L20	NA	NA	NA	NA
WP_002289312.1\|1327034_1328372_+	hypothetical protein	NA	NA	NA	NA
WP_010717983.1\|1328419_1330549_+	hydantoinase/oxoprolinase	NA	NA	NA	NA
WP_002302159.1\|1330523_1331213_+	hypothetical protein	NA	NA	NA	NA
WP_002289316.1\|1331619_1332306_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_002315615.1\|1332441_1332636_-	hypothetical protein	NA	NA	NA	NA
WP_002289317.1\|1332685_1333126_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_002319484.1\|1333129_1333975_-	NAD(P)H-hydrate dehydratase	NA	NA	NA	NA
WP_002294157.1\|1334123_1335542_+	dipeptidase PepV	NA	NA	NA	NA
WP_002289860.1\|1335598_1336546_-	glycosyltransferase	NA	NA	NA	NA
WP_002289862.1\|1336768_1337119_-	peptidase	NA	NA	NA	NA
WP_002294156.1\|1337318_1338398_+	glutamyl aminopeptidase	NA	NA	NA	NA
WP_002287837.1\|1338540_1338861_+	thioredoxin family protein	NA	NA	NA	NA
WP_002287838.1\|1338882_1339347_+	universal stress protein	NA	NA	NA	NA
WP_010717984.1\|1339551_1340157_+	DUF4479 domain-containing protein	NA	NA	NA	NA
WP_002325236.1\|1340195_1341482_-	PDZ domain-containing protein	A0A1B1IT49	uncultured_Mediterranean_phage	5.7e-22	30.2
WP_002287841.1\|1341909_1342389_+	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_101735313.1\|1342591_1343794_+	PD-(D/E)XK nuclease family protein	NA	NA	NA	NA
WP_002303791.1\|1343775_1344735_-\|transposase	IS30-like element IS6770 family transposase	NA	NA	NA	NA
WP_010724830.1\|1344983_1345490_+	hypothetical protein	NA	NA	NA	NA
WP_016631482.1\|1345812_1346202_-	hypothetical protein	NA	NA	NA	NA
WP_047021760.1\|1346360_1347104_+	hypothetical protein	NA	NA	NA	NA
WP_002295755.1\|1347140_1347638_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_101735314.1\|1347693_1348602_-\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_002330719.1\|1348827_1350006_-\|transposase	IS256-like element ISEfm2 family transposase	NA	NA	NA	NA
WP_002323137.1\|1350462_1351974_+	glutamate:gamma-aminobutyrate antiporter	NA	NA	NA	NA
WP_002287852.1\|1351986_1353387_+	glutamate decarboxylase	NA	NA	NA	NA
WP_101735315.1\|1353551_1354988_-	DNA-binding protein	NA	NA	NA	NA
WP_002322607.1\|1355218_1356178_+\|transposase	IS30-like element IS6770 family transposase	NA	NA	NA	NA
WP_002291914.1\|1356542_1357481_+	2-dehydropantoate 2-reductase	NA	NA	NA	NA
WP_101735316.1\|1357493_1358549_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_010725409.1\|1358814_1359450_+	DUF998 domain-containing protein	NA	NA	NA	NA
WP_010725408.1\|1359640_1360432_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_086956687.1\|1362744_1363907_-\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	1.6e-79	51.3

DBSCAN-SWA_5

1603365 : 1705433

Paenibacillus_phage(18.18%)

transposase,terminase,tRNA,protease,head,lysis,integrase,tail,capsid,portal

attL 1603238:1603297|attR 1673441:1674807

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1603238:1603297	attL	NA	NA	NA	NA
WP_086956687.1\|1603365_1604528_-\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	1.6e-79	51.3
WP_002352139.1\|1604722_1604848_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_002326335.1\|1604921_1605815_+	class C sortase	NA	NA	NA	NA
WP_002291233.1\|1605998_1606673_+	response regulator transcription factor	NA	NA	NA	NA
WP_010718316.1\|1606690_1607716_+	sensor histidine kinase	NA	NA	NA	NA
WP_002286769.1\|1607804_1608671_+	glucose transporter GlcU	NA	NA	NA	NA
WP_002286768.1\|1608707_1610084_+	amino acid permease	NA	NA	NA	NA
WP_002286766.1\|1610184_1611381_-	toxic anion resistance protein	A0A2K9VCT6	Lactobacillus_phage	3.9e-33	29.1
WP_010718315.1\|1611504_1612167_-\|lysis	5-bromo-4-chloroindolyl phosphate hydrolysis protein	NA	NA	NA	NA
WP_002325125.1\|1612394_1612958_+	NUDIX hydrolase	NA	NA	NA	NA
WP_002286760.1\|1612970_1613255_+	hypothetical protein	NA	NA	NA	NA
WP_002291218.1\|1613273_1613966_+	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_002291217.1\|1613977_1614523_+	cysteine hydrolase	G3MA16	Bacillus_virus	2.6e-24	37.4
WP_101735332.1\|1614795_1618062_+	right-handed parallel beta-helix repeat-containing protein	NA	NA	NA	NA
WP_002318905.1\|1618844_1620752_-	peptidase M13	E3T4I7	Cafeteria_roenbergensis_virus	6.1e-81	31.1
WP_010718313.1\|1620881_1621757_+	hypothetical protein	NA	NA	NA	NA
WP_002286741.1\|1621836_1622811_+	ribose-phosphate diphosphokinase	A0A1V0SHF7	Hokovirus	2.0e-40	32.2
WP_002286738.1\|1622999_1624136_+	cysteine desulfurase	NA	NA	NA	NA
WP_002286736.1\|1624272_1624617_+	DUF1831 domain-containing protein	NA	NA	NA	NA
WP_010718312.1\|1624887_1626174_+	multidrug efflux MFS transporter EfmA	A0A1B0RXG2	Streptococcus_phage	1.4e-68	36.9
WP_002291205.1\|1626311_1626911_-	metallophosphatase	A0A288TXW7	Enterococcus_phage	5.6e-33	40.0
WP_010718311.1\|1627314_1628436_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_010718310.1\|1628681_1630103_+	arginine-ornithine antiporter	NA	NA	NA	NA
WP_010718309.1\|1630116_1631235_+	aminotransferase	NA	NA	NA	NA
WP_002325116.1\|1631294_1632587_-	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_010718308.1\|1632736_1633297_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_002291196.1\|1633425_1633803_+	DUF1033 family protein	NA	NA	NA	NA
WP_033583050.1\|1633735_1635808_+	DNA topoisomerase III	NA	NA	NA	NA
WP_002289773.1\|1636018_1636966_-	glycosyltransferase family 2 protein	V5USA4	Oenococcus_phage	5.0e-84	51.0
WP_002291193.1\|1637211_1637676_+	methylated-DNA--[protein]-cysteine S-methyltransferase	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	8.8e-18	37.2
WP_002291191.1\|1637737_1638781_-	putative sulfate exporter family transporter	NA	NA	NA	NA
WP_010718307.1\|1639157_1640123_-	TDT family transporter	NA	NA	NA	NA
WP_002291186.1\|1640356_1641202_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002291183.1\|1641392_1642580_+	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_002295166.1\|1642585_1642942_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	2.7e-22	42.3
WP_002291179.1\|1642943_1643282_+	glycine cleavage system protein H	NA	NA	NA	NA
WP_002304234.1\|1643676_1644711_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	4.2e-28	35.1
WP_002287674.1\|1644703_1645390_+	ABC transporter permease	NA	NA	NA	NA
WP_002287678.1\|1645413_1646262_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002287679.1\|1646458_1647232_+	Fe-S cluster assembly ATPase SufC	A0A2R8FG22	Brazilian_cedratvirus	2.1e-08	28.8
WP_101735333.1\|1647244_1648531_+	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
WP_010718306.1\|1648527_1649763_+	cysteine desulfurase	Q2XUY6	environmental_halophage	1.0e-113	48.0
WP_002287684.1\|1649749_1650220_+	SUF system NifU family Fe-S cluster assembly protein	NA	NA	NA	NA
WP_002287686.1\|1650224_1651616_+	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
WP_002336282.1\|1651712_1652864_-\|integrase	site-specific integrase	A0A1S5S7K9	Streptococcus_phage	2.9e-54	33.1
WP_025479542.1\|1652907_1653525_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002336284.1\|1653731_1653956_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_073463006.1\|1653952_1654225_+	DNA-binding protein	NA	NA	NA	NA
WP_073984966.1\|1654300_1654546_+	hypothetical protein	NA	NA	NA	NA
WP_101735334.1\|1654683_1654899_+	hypothetical protein	NA	NA	NA	NA
WP_101735335.1\|1654895_1655801_+	hypothetical protein	V5URM4	Enterococcus_phage	1.5e-05	38.2
WP_101735336.1\|1655797_1657189_+	DNA primase	A0A0M4RE09	Enterococcus_phage	4.4e-36	34.1
WP_101735337.1\|1657490_1657898_+	DUF3206 domain-containing protein	NA	NA	NA	NA
WP_101735338.1\|1657900_1658098_+	hypothetical protein	NA	NA	NA	NA
WP_101735339.1\|1658119_1658500_+	endonuclease	A0A1J0MFT4	Staphylococcus_phage	4.2e-18	40.7
WP_005879181.1\|1658634_1658790_+	DUF2292 domain-containing protein	NA	NA	NA	NA
WP_073462992.1\|1658858_1659332_+\|terminase	phage terminase small subunit P27 family	NA	NA	NA	NA
WP_101735340.1\|1659328_1661023_+\|terminase	terminase large subunit	A0A2H4JBN3	uncultured_Caudovirales_phage	4.5e-128	43.6
WP_002306148.1\|1660988_1661174_+	hypothetical protein	NA	NA	NA	NA
WP_101735341.1\|1661177_1662353_+\|portal	phage portal protein	A0A1D6Z2A2	Staphylococcus_phage	2.1e-63	35.3
WP_101735342.1\|1662345_1663869_+\|capsid	phage major capsid protein	A0A1W6JPR8	Staphylococcus_phage	1.1e-48	37.4
WP_101735343.1\|1663922_1664207_+\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_101735344.1\|1664193_1664529_+\|head	phage head closure protein	V5UQC7	Enterococcus_phage	4.7e-13	36.6
WP_101735345.1\|1664530_1664725_+\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_101735346.1\|1664838_1665531_+	hypothetical protein	Q4ZB12	Staphylococcus_virus	1.3e-12	26.8
WP_101735347.1\|1665549_1666203_+	hypothetical protein	NA	NA	NA	NA
WP_002327677.1\|1666462_1667602_-\|integrase	site-specific integrase	A0A1S5S7K9	Streptococcus_phage	6.7e-59	35.7
WP_094932120.1\|1668135_1669298_-\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	2.7e-79	51.3
WP_002327679.1\|1669944_1670259_+	hypothetical protein	NA	NA	NA	NA
WP_033603054.1\|1670311_1671070_-	hypothetical protein	NA	NA	NA	NA
WP_002313380.1\|1671190_1671436_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002314576.1\|1671511_1671790_+	hypothetical protein	NA	NA	NA	NA
WP_086956687.1\|1672209_1673371_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	1.6e-79	51.3
WP_002316489.1\|1673802_1674228_+	hypothetical protein	NA	NA	NA	NA
WP_101735348.1\|1674837_1676334_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
1673441:1674807	attR	NA	NA	NA	NA
WP_010718304.1\|1676688_1680141_+	VWA domain-containing protein	NA	NA	NA	NA
WP_002327400.1\|1680143_1681565_+	SpaH/EbpB family LPXTG-anchored major pilin	NA	NA	NA	NA
WP_101735349.1\|1681561_1683439_+	SpaH/EbpB family LPXTG-anchored major pilin	NA	NA	NA	NA
WP_010718303.1\|1683530_1684361_+	class C sortase	NA	NA	NA	NA
WP_101735350.1\|1685025_1686188_-\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	1.0e-78	50.9
WP_010718300.1\|1687581_1688988_+	6-phospho-beta-galactosidase	NA	NA	NA	NA
WP_010718299.1\|1689304_1690204_+	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_010718298.1\|1690535_1690826_-	hypothetical protein	NA	NA	NA	NA
WP_071243184.1\|1691372_1691609_+	helix-turn-helix transcriptional regulator	A0A097PBE6	Streptococcus_pyogenes_phage	1.5e-13	53.4
WP_010718296.1\|1691845_1693960_+\|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	1.2e-117	38.9
WP_025480325.1\|1694527_1694764_+	hypothetical protein	NA	NA	NA	NA
WP_002314345.1\|1694982_1695174_+	hypothetical protein	NA	NA	NA	NA
WP_101735351.1\|1695691_1697041_+	replication protein RepR	NA	NA	NA	NA
WP_002311030.1\|1697084_1697279_+	hypothetical protein	NA	NA	NA	NA
WP_077150478.1\|1697410_1699252_+	type IA DNA topoisomerase	A0A1X9I6W8	Streptococcus_phage	2.1e-102	43.8
WP_038809792.1\|1699808_1699997_+	hypothetical protein	NA	NA	NA	NA
WP_002307506.1\|1700721_1701144_+	cupin domain-containing protein	Q2I8C5	Bacillus_phage	2.4e-38	58.5
WP_025370695.1\|1701227_1701881_+	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	6.2e-25	36.9
WP_002311027.1\|1701877_1702642_+	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_002318453.1\|1702716_1702830_+	hypothetical protein	NA	NA	NA	NA
WP_094932120.1\|1703151_1704313_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	2.7e-79	51.3
WP_158296032.1\|1704539_1705433_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	2.0e-79	51.3

DBSCAN-SWA_6

2061262 : 2071078

Streptococcus_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002293942.1\|2061262_2061979_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.0e-33	35.7
WP_002288588.1\|2061978_2063427_+	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	1.7e-19	29.3
WP_101735384.1\|2063496_2064006_-	hypothetical protein	NA	NA	NA	NA
WP_002297641.1\|2063995_2064721_-	hypothetical protein	NA	NA	NA	NA
WP_101735385.1\|2064943_2067064_-	LTA synthase family protein	W6LM83	Streptococcus_phage	2.8e-220	58.1
WP_002322842.1\|2067293_2068472_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	5.1e-102	48.9
WP_002293935.1\|2068487_2069246_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	8.5e-26	36.9
WP_002288577.1\|2069268_2069754_+\|tRNA	Cys-tRNA(Pro) deacylase	NA	NA	NA	NA
WP_002288576.1\|2069824_2071078_-	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	7.7e-24	55.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage