CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_AP018113	Burkholderia stabilis strain FERMP-21014 chromosome 3	0 crisprs	cas14j,WYL	0	0	0	0
NZ_AP018112	Burkholderia stabilis strain FERMP-21014 chromosome 2	2 crisprs	csa3,c2c9_V-U4,DinG,cas3,Cas14u_CAS-V,cas14j	0	0	1	0
NZ_AP018111	Burkholderia stabilis strain FERMP-21014 chromosome 1	6 crisprs	DEDDh,c2c9_V-U4,csa3,WYL,cas3	1	2	255	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_AP018112_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP018112_1

836625-836803

Orphan

Consensus_repeat	Method
CTGCTGCTCGAGCATGGCGCCGACCCGAACGA	PILER-CR

2 spacers

The CRISPR arrays of NZ_AP018112_1

>merge|NZ_AP018112|1|836625-836803|PILER-CR
GGCGCCGACCCGAACGACGGCGAATCGCTGTATCACTCGCTGGAAAACCCCGCATGCACGCGCCTGCTGCTCGAGCATGGCGCACGGGTGGCCGGGACGCACGCGTTGCGGCGCGCGCTCGACATGCGTGACGCGGCCGCGCTCGAACTGCTGCTCGCGCATGGCGGCGACCCGAACGA

>NZ_AP018112|1|1|836625-836803|PILER-CR
GGCGCCGACCCGAACGACGGCGAATCGCTGTA	TCACTCGCTGGAAAACCCCGCATGCACGCGCCTGCTGCTCGAGCAT
GGCGCACGGGTGGCCGGGACGCACGCGTTGCG	GCGCGCGCTCGACATGCGTGACGCGGCCGCGCTCGAACTGCTGCTCGCGCATGGCGGCGACCCGA
ACGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP018112.1\|WP_096473743.1\|831678_833055_-\|sensor-histidine-kinase-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|182388
NZ_AP018112.1\|WP_096473749.1\|838933_839200_+\|YodC-family-protein	unknown	unknown	gnl\|CDD\|378312
NZ_AP018112.1\|WP_096473753.1\|842494_843226_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP018112.1\|WP_047902647.1\|834353_835214_+\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
NZ_AP018112.1\|WP_096473745.1\|833944_834298_+\|NirD/YgiW/YdeI-family-stress-tolerance-protein	unknown	unknown	gnl\|CDD\|225653
NZ_AP018112.1\|WP_047902652.1\|840521_840848_-\|superinfection-immunity-protein	unknown	unknown	gnl\|CDD\|379585
NZ_AP018112.1\|WP_096473742.1\|830890_831337_-\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NZ_AP018112.1\|WP_096473746.1\|835269_835695_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_AP018112.1\|WP_096473744.1\|833051_833714_-\|response-regulator	unknown	unknown	gnl\|CDD\|182612
NZ_AP018112.1\|WP_096473739.1\|827316_828207_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176176
NZ_AP018112.1\|WP_096473754.1\|843283_844354_+\|nitronate-monooxygenase	unknown	unknown	gnl\|CDD\|240081
NZ_AP018112.1\|WP_096473750.1\|839319_840495_+\|cytochrome-P450	unknown	unknown	gnl\|CDD\|225035
NZ_AP018112.1\|WP_096473741.1\|830487_830856_-\|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl\|CDD\|367760
NZ_AP018112.1\|WP_096473756.1\|845950_847060_+\|malate/lactate/ureidoglycolate-dehydrogenase	unknown	unknown	gnl\|CDD\|182240
NZ_AP018112.1\|WP_096473751.1\|840938_841358_-\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|238779
NZ_AP018112.1\|WP_096473740.1\|828335_829247_+\|PenA-family-class-A-beta-lactamase	unknown	unknown	gnl\|CDD\|185339
NZ_AP018112.1\|WP_096473752.1\|841472_842432_+\|transcriptional-regulator-FtrA	unknown	unknown	gnl\|CDD\|181818
NZ_AP018112.1\|WP_047902641.1\|829727_829928_-\|membrane-protein	unknown	unknown	gnl\|CDD\|377540
NZ_AP018112.1\|WP_096473748.1\|837727_838588_+\|isocitrate-lyase/phosphoenolpyruvate-mutase-family-protein	unknown	unknown	gnl\|CDD\|379346
NZ_AP018112.1\|WP_096473755.1\|844434_845889_+\|M20-family-metallopeptidase	unknown	unknown	gnl\|CDD\|349931

Protein	Function_ID	Function_description	E-value
NZ_AP018112.1\|WP_096473743.1\|831678_833055_-\|sensor-histidine-kinase-N-terminal-domain-containing-protein	gnl\|CDD\|182388	PRK10337, PRK10337, sensor protein QseC; Provisional.	3.41155e-63
NZ_AP018112.1\|WP_096473749.1\|838933_839200_+\|YodC-family-protein	gnl\|CDD\|378312	pfam09926, DUF2158, Uncharacterized small protein (DUF2158). Members of this family of prokaryotic proteins have no known function.	2.45481e-27
NZ_AP018112.1\|WP_047902647.1\|834353_835214_+\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	3.20407e-51
NZ_AP018112.1\|WP_096473745.1\|833944_834298_+\|NirD/YgiW/YdeI-family-stress-tolerance-protein	gnl\|CDD\|225653	COG3111, COG3111, Periplasmic protein with OB-fold [Function unknown].	6.78807e-24
NZ_AP018112.1\|WP_047902652.1\|840521_840848_-\|superinfection-immunity-protein	gnl\|CDD\|379585	pfam14373, Imm_superinfect, Superinfection immunity protein. This family includes the E. coli bacteriophage T4 superinfection immunity (imm) protein. When E. coli is sequentially infected with two T-even type bacteriophage the DNA of the superinfecting phage is excluded from the host, into the periplasmic space. The immunity protein plays a role in this process.	1.08951e-17
NZ_AP018112.1\|WP_096473742.1\|830890_831337_-\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	3.16061e-18
NZ_AP018112.1\|WP_096473746.1\|835269_835695_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.2502e-10
NZ_AP018112.1\|WP_096473744.1\|833051_833714_-\|response-regulator	gnl\|CDD\|182612	PRK10643, PRK10643, two-component system response regulator PmrA.	3.80711e-84
NZ_AP018112.1\|WP_096473739.1\|827316_828207_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176176	cd08487, PBP2_BlaA, The C-terminal substrate-binding domain of LysR-type trnascriptional regulator BlaA which involved in control of the beta-lactamase gene expression; contains the type 2 periplasmic binding fold. This CD represents the C-terminal substrate binding domain of LysR-type transcriptional regulator, BlaA, that involved in control of the expression of beta-lactamase genes, blaA and blaB. Beta-lactamases are responsible for bacterial resistance to beta-lactam antibiotics such as penicillins. The blaA gene is located just upstream of blaB in the opposite direction and regulates the expression of the blaB. BlaA also negatively auto-regulates the expression of its own gene, blaA. BlaA (a constitutive class A penicllinase) belongs to the LysR family of transcriptional regulators, whereas BlaB (an inducible class C cephalosporinase or AmpC) can be referred to as a penicillin binding protein but it does not act as a beta-lactamase. The topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	5.33381e-120
NZ_AP018112.1\|WP_096473754.1\|843283_844354_+\|nitronate-monooxygenase	gnl\|CDD\|240081	cd04730, NPD_like, 2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase family that reduce a range of alternative electron acceptors. Most use FAD/FMN as a cofactor and NAD(P)H as electron donor. Some contain 4Fe-4S cluster to transfer electron from FAD to FMN.	2.73448e-76
NZ_AP018112.1\|WP_096473750.1\|839319_840495_+\|cytochrome-P450	gnl\|CDD\|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	7.85118e-32
NZ_AP018112.1\|WP_096473741.1\|830487_830856_-\|antibiotic-biosynthesis-monooxygenase	gnl\|CDD\|367760	pfam03992, ABM, Antibiotic biosynthesis monooxygenase. This domain is found in monooxygenases involved in the biosynthesis of several antibiotics by Streptomyces species. It's occurrence as a repeat in Streptomyces coelicolor SCO1909 is suggestive that the other proteins function as multimers. There is also a conserved histidine which is likely to be an active site residue.	1.48902e-13
NZ_AP018112.1\|WP_096473756.1\|845950_847060_+\|malate/lactate/ureidoglycolate-dehydrogenase	gnl\|CDD\|182240	PRK10098, PRK10098, putative dehydrogenase; Provisional.	0
NZ_AP018112.1\|WP_096473751.1\|840938_841358_-\|rhodanese-like-domain-containing-protein	gnl\|CDD\|238779	cd01521, RHOD_PspE2, Member of the Rhodanese Homology Domain superfamily. This CD includes the putative rhodanese-like protein, Psp2, of Yersinia pestis biovar Medievalis and other similar uncharacterized proteins.	3.89598e-60
NZ_AP018112.1\|WP_096473740.1\|828335_829247_+\|PenA-family-class-A-beta-lactamase	gnl\|CDD\|185339	PRK15442, PRK15442, beta-lactamase TEM; Provisional.	6.14113e-79
NZ_AP018112.1\|WP_096473752.1\|841472_842432_+\|transcriptional-regulator-FtrA	gnl\|CDD\|181818	PRK09393, ftrA, transcriptional activator FtrA; Provisional.	0
NZ_AP018112.1\|WP_047902641.1\|829727_829928_-\|membrane-protein	gnl\|CDD\|377540	pfam05656, DUF805, Protein of unknown function (DUF805). This family consists of several bacterial proteins of unknown function.	0.000134545
NZ_AP018112.1\|WP_096473748.1\|837727_838588_+\|isocitrate-lyase/phosphoenolpyruvate-mutase-family-protein	gnl\|CDD\|379346	pfam13714, PEP_mutase, Phosphoenolpyruvate phosphomutase. This domain includes the enzyme Phosphoenolpyruvate phosphomutase (EC:5.4.2.9). This protein has been characterized as catalyzing the formation of a carbon-phosphorus bond by converting phosphoenolpyruvate (PEP) to phosphonopyruvate (P-Pyr). This enzyme has a TIM barrel fold.	8.31621e-83
NZ_AP018112.1\|WP_096473755.1\|844434_845889_+\|M20-family-metallopeptidase	gnl\|CDD\|349931	cd05682, M20_dipept_dapE, uncharacterized M20 dipeptidase. Peptidase M20 family, unknown dipeptidase-like subfamily (inferred by homology to be dipeptidases). M20 dipeptidases include a large variety of bacterial enzymes including cytosolic nonspecific dipeptidase (CNDP), Xaa-methyl-His dipeptidase (anserinase),and canosinase. These dipeptidases have been shown to act on a wide range of dipeptides, but not larger peptides. For example, anserinase mainly catalyzes the hydrolysis of N-alpha-acetylhistidine while carnosinase degrades beta-alanyl-L-histidine. This family includes dapE (Lpg0809) from Legionella pneumophila.	0

>NZ_AP018112.1|WP_096473746.1|835269_835695_+|GNAT-family-N-acetyltransferase
MTLTYEVTDAGDANVRKQIVAPLVRFNERQAGPADFRPLAVIVTDADGAVAGGLWGGTAFGWLHVDLLVVPEEARGQGAGTRIMDLAEAEAVARGCHSAWLDTFEFQARPFYEKRGYVRFGELPDYPVGHTRIFLTKKLAG
>NZ_AP018112.1|WP_047902647.1|834353_835214_+|MurR/RpiR-family-transcriptional-regulator
MAANFDELASRIRAQFSELSPQFQAGAAFLLDHPDEVATSSMRKVAQRAQVQPASLVRLAQQFGFPGWNELRDLCVARVRTRPEPLTQRARSLVRPDAKASLAHDLLAAQQHNLSATAAQNEHALADAARLIRKASHVHVAGFRSCYPVAFGFVYGYRLFRPTVSLLNGVAGSLEMELRTIAKQSVTVVVSFAPYSAEATRVAQAAKAQGSRIVAITDSAVSPIALHADAQLIFTHDSPSFFPSLVAAHAMAEALVAQLLALEGSDAIAALERTEAELHAKGAYVV
>NZ_AP018112.1|WP_096473745.1|833944_834298_+|NirD/YgiW/YdeI-family-stress-tolerance-protein
MKHLTRILAVALAVLPAAVYAEYTGPSTLTTTTVKELLANGKDDQHVQLQGRIVKHAGGEDYEFADATGTIRVEIDNKLWAAGQPVSDKSEVKLTGEFERKWSGKVKVDADHVEVLH
>NZ_AP018112.1|WP_096473744.1|833051_833714_-|response-regulator
MRVLLVEDDPLIGSGLEQGLKQEGFAVDWVKDGDAASLALRSTGYGLLLLDLGLPNRDGLSVLAALRRRDETLPAIIITARDGVPDRIAGLDSGADDYLVKPFELDELLARIRAVNRRHAGRAQTTLAIGPLRLDPVKHLVWLDDEEVPLSPKEFVLLHELMREPGAVISREQFEERLYSWGEEIESNAVQVHIHNLRKKLGHDMIRTVRGVGYRIGDGA
>NZ_AP018112.1|WP_096473743.1|831678_833055_-|sensor-histidine-kinase-N-terminal-domain-containing-protein
MTGVQRAIARWRNASLRRRLLMWLLPAACVIGLVASAGTYWGALRELDDLLDDQMRSMSKQIVVGPNGELSFSNRANGKHGFEASDPDAVLLQVWRNGTLVYSTDRDSTLPPPAQKGIASVDVGGQPWRTYVTERGGTTIRLAQARHARWEAIAGIAVHLLWPVFSMLPVLAIGLWFGIGAGLRPLRTIASGLKRRNANNLEPVDVASMPNEVRPLAEAINDLLARLDRSFTLQRHFIADAAHELRTPIMGLSIQSNLLRRAATAEERERILAQIHAGTTRLGHLAEQLLTLARLEPDAQAATSAAAPVDLAALCRSVVADRARVADAHRIDLGAIVAAPVMAAGNIDTLRVLLNNLVDNAIRYAGDGARVDVSARIDGTTPVLEIADDGPGIPEAERTDVWERFYRGEGAQAVTSSGSGLGLSIVKRIAEQHRATVALSTTRGGRGLTVTVRFPAPV
>NZ_AP018112.1|WP_096473742.1|830890_831337_-|winged-helix-turn-helix-transcriptional-regulator
MTKSEKLTTVALSVFRLNGLLIEWGNAFAGPHGLTSARWQVLGAISMAPEAPNIPQIADAMGITRQAVLKQINVLVDEGLVRSLPNPAHKRSPLYSLTPRGDAAYQAVVEQWQQHVRDIAGDFSSADLDAAIRVLSAMSSAHGQDGHA
>NZ_AP018112.1|WP_096473741.1|830487_830856_-|antibiotic-biosynthesis-monooxygenase
MPQFKPMDPAFPIQQQIAIDAEPVVLVNVFTLDPADEADFLAVWKDDAEFMKRQPGFISTQLHRALGDSPTYLNYAIWESTHAFRAAFTHPEFVAKLSAYPSSAVASPHLFQKVGVASICTA
>NZ_AP018112.1|WP_047902641.1|829727_829928_-|membrane-protein
MEHFTAWQLLVSLVLVAVVVYPYVRIVRRTGHSGWWILTMFVPVLNFIMLWVFAFARWPTVDDRQG
>NZ_AP018112.1|WP_096473740.1|828335_829247_+|PenA-family-class-A-beta-lactamase
MTYSSKRRTLLLAAATAPLVLTVTACASSQAAAPDEAAMPNVAAAATFAQLERDAGGRLGVCAIDTASGRRVAHRADERFPFCSTFKAMLSAAVLAQSVARPGLLQQRVTYGKADLVNYSPVTGKHVDAGMTVAELCEATIQYSDNAAANLLMKLIGGPSAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLTLGDALPAAQRAQLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPTRAPIVLVVYYTQAHADARAKDDVIADVARVVVEALG
>NZ_AP018112.1|WP_096473739.1|827316_828207_-|LysR-family-transcriptional-regulator
MTKLRPHLPLNALRAFESSARHLNFTRAGLELSVTQAAVSQQVRSLEERLGCTLFTRLPRGLGLTDEGRALLPVLSDAFSRIETVLKQFDGGRFHEVLTLGVVGTFAIGWLMPRLKQFGDTHPFVELRLRTNNNVVDLAAEGLDFAIRFGVGNWPATRNERLLDAPLTALCAPDIARRLAQPADLANETLLRSYRTDEWLGWFDAAQLEPWAVNGPVFDSSRLMVEAAMQGAGVALAPACMFARELQLGLLARPLDIDVRAGGYWLTSLKSKPLTPAMTLFRDWIAAEAADTAPAA
>NZ_AP018112.1|WP_096473748.1|837727_838588_+|isocitrate-lyase/phosphoenolpyruvate-mutase-family-protein
MTRSDLQARQAEVFRTLHTRPGAFIIPNPWDAGTARLLAMAGFEALATTSAGYAFSKGQPDNAIDRDAMLDHIADLVAAGGLPVSADLENGFGDAPDTVAETIRLAAEAGAVGGSIEDATGRADAPIYAHDAAVERIAAAVDAARALPFPFTLTARCENYLHGRRDLADTIARLVAYRDAGADVLYAPGITDAAEIAAVTQAVGAPVNVVMGLQGGLLSLDELAALGVKRVSVGGALARAALGAFLRAATEMARDGTFTFTQAAVPGRDINRWFAAPDNSPVSFGE
>NZ_AP018112.1|WP_096473749.1|838933_839200_+|YodC-family-protein
MTIRENQRVRFRVGDVVTLKTGGPRMTVTYAGPVVFDDGEWVICQWFDESGEFRQEMFHHDTVVPEPRAISAGRVRMRMQSHRYRSAA
>NZ_AP018112.1|WP_096473750.1|839319_840495_+|cytochrome-P450
MNSNPTDPIAAVTHRDPYPYYAALVDGPPLAFDATLGLWVASRAATVTAVLGHPACRVRPLDAPVPPALRGTTAGALFGELVRMNDGASRHDVPKQALRTALAPVDTGKLRDRAAQLAARRLPAPGDADALNAWCMTVPVCAVADLLGFDETQLDDVAARVVDFVAALSPLSDAAALARASDGARQLLDRMTERVAQTHAHDGTLVAAVQQAARASGWEASGALVANLVGLLSQTCEATAAWLGNTLVAWNGEAETARVAPDDAALDTFVAEVGRFDAPVQNTRRFVASRTTIEGVTVDAGDAILVVLAAANRDPAVHRDPHRLMPGRAAGTNFGFGTGPHGCPGERIARAMTAGAFAAWLRAGGWPPRDGLTWNYRASTNVRMPTFDAAR
>NZ_AP018112.1|WP_047902652.1|840521_840848_-|superinfection-immunity-protein
MNDAVLIQVAGSVVAIALYFVPAVIADRRGRHDKLTIAMFNALFGWTGIGWLMTLYWACQPNPRTDVAQTILAKRRSISMRTFSTGLVERVQRRVAAQEQWAEKQGCR
>NZ_AP018112.1|WP_096473751.1|840938_841358_-|rhodanese-like-domain-containing-protein
MSFVTDVPAADSPAALAHFAASLRFETDCWDVHDALASGAPDFVLLDVRGPDQFAAGHVPGARNLPRRKIIASKLAGYPAGTLFVVYCAGPHCNGAARAAIELARLGRPVKLMIGGVTGWLDEGFELSNELHPADAEAR
>NZ_AP018112.1|WP_096473752.1|841472_842432_+|transcriptional-regulator-FtrA
MHNHLVVALAYDRLCTFEFGCVVELFALERPELGVDWYRFAVCASEPGPVRAAGGITVAAPYRLATLDRADTIVIPGWRDSEELPPEPLLKKLRAAHRRGARLCSICSGVFVLAAAGVLDGLTVTTHWRYAERLQARYPALRVNPDALYVDEGQIVTSAGSAAGLDMLLHLVRRDHGGAIANRVAQRLVLPPHRDGGQAQFVPRPVAPGGSDRLAKLIDWMRVHAAEPHTLASLAAQAAMSTRTLQRQFADATGMSPLAWLIRERVNVAKDILEAQPALSLAQVAARAGFGSEESLRRHFRRVAATSPAAYRRGMDRGG
>NZ_AP018112.1|WP_096473753.1|842494_843226_+|hypothetical-protein
MGLLEKLFGKKSRAEEASAAQVPSTGEQDGRDEQNGPDIAAELAPALAAYQAGRHEAAIAGAAPYAERLADAARLCALAYSAMHRHAEAFPYWLALFEREPSAHNAVQLATTSVMCGEVKRGEAWMQKAAQVNHETREQSDVAARVNFISALMQSGHLHEALPHIAWMRDVYGQVRITDSTFLTMRGIPFFPSFLEKSLEILKATQPADAIAPWYGALTGKLDEAGEAQLAAWVDQLPAQPAG
>NZ_AP018112.1|WP_096473754.1|843283_844354_+|nitronate-monooxygenase
MTMLPSRLPLIQAPMVGSLSPLAIAVCEAGGLGSLACAALGPQQLSDEIAAIRARTPAPFNVNFFCHTPPAPDAEVDARWRAALAGYYAQAGLDPADVKGGPGRAPFDDAMCAVVEELRPAVVSFHFGLPDDALLERVRRTGALVVSSATTVEEARWLDARGVDAIVAQGAEAGGHRGMFLTDDIHAQPGLFALLPQIVDAVRAPVIAAGAIADGRGIAAAFALGARAVQIGTGYLLTPQAGRSAQHRAAVRAARDDGTRVTNLYTGRPARGLLTRFMREQGPMSALAPAFPLATAAVDPLRGAFERQGRDDFSLLWSGEAAALAREEDAGELTRRLWSDALACASGLRDAFPQTV
>NZ_AP018112.1|WP_096473755.1|844434_845889_+|M20-family-metallopeptidase
MTSVDTTPVLDHDKLVTFIERKWNDEILHALTDYIAIPAKSPAFDPDWEKRGYLERVVTDAAQWAERQPVKGLKLEIVRLPGRTPVIFFESPATRSGSTDTILLYGHLDKQPEFDGWRADLGPWTPKFENGKLYGRGGADDGYAIYASLAALGALDEQGIERPRCVGLIETCEESGSYDLLPYVDALRDRLGQVSLVVCLDSGAGNYDQMWLTTSLRGLVSGDLQVEVLEEGIHSGVYGGIAPSSFRVMRQLFERLEDAKNGNLLPGVFHCEIPSSRVREADAAAAILGDAVWKGLPWACGADGKPVLPTTTDPREALLNSTWRPSLSVTGAAGMPALADAGNVLRPRTAFKLSLRLPPLVDAAQAVQQLKELLELDPPYNAKVTFKPDAGAATGWAAPDLSPWLASSLDAASRRHFGADCAYMGLGGTIPLMNVLQEGFPSAQFMVCGVLGPKSNAHGPNEFLHVPYAKKLTAAVADVIASAR
>NZ_AP018112.1|WP_096473756.1|845950_847060_+|malate/lactate/ureidoglycolate-dehydrogenase
MTALPTPDTEPLRMRAEPLHAFVAALWERAGSSEREARLVADHLVGANLAGHDSHGIGMIPNYVASWREGQLQLNGHASIVRDGGAVLTIDGGRGFGQVIAFEAMVEGIERARRMGICAIGLRDVHHLGRIGHWAEQCARSGLVSFHFVNVPGDLLVAPLHGTDPRFGTNPFCAAYPRAGRAPLLLDFATSAIAYGKTRVAYNQGKRVPAGSLIDHRGQPTDDPAVMHEQPFGALLPFGLHKGYALAAMCEIFGGALVGGHTTYGDTLQKTSAIVNGMLSVLIDPKAFDAADAEREADAFVAWAKASPQAGGAPVQVPGEPEETSRAARGAGGIPVDHATWRQIRDSAAAVGFDDAALDAWTQRCIGAA

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Crispr_ID: NZ_AP018112_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP018112_2

3142275-3142415

TypeV

Consensus_repeat	Method
TACGGGCATCCGGCCGGCGGGCA	CRISPRCasFinder

2 spacers

cas14j

The CRISPR arrays of NZ_AP018112_2

>merge|NZ_AP018112|2|3142275-3142415|CRISPRCasFinder
GTCGCGCATCCGCGCGGCGGCCTACTGGAAGCGCGGCGCGGCGGCCGTGCACGAAACGCTGGAAGATTGACGCATACGGGCATCCGGCCGGCGGGCATCCCGCATACGGGCACCCGGCGACGGGCATCCGCCTTACGGGCA

>NZ_AP018112|2|1|3142275-3142415|CRISPRCasFinder
GTCGCGCATCCGCGCGGCGGCCT	ACTGGAAGCGCGGCGCGGCGGCCGTGCACGAAACGCTGGAAGATTGACGCA
TACGGGCATCCGGCCGGCGGGCA	TCCCGCATACGGGCACCCGGC
GACGGGCATCCGCCTTACGGGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP018112.1\|WP_047902085.1\|3146568_3147783_+\|patatin-like-phospholipase-family-protein	unknown	unknown	gnl\|CDD\|132848
NZ_AP018112.1\|WP_096475719.1\|3134068_3136495_-\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|273805
NZ_AP018112.1\|WP_096475483.1\|3138704_3139280_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP018112.1\|WP_096475491.1\|3145429_3146482_-\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	cas14j	-	gnl\|CDD\|223747
NZ_AP018112.1\|WP_096475484.1\|3139900_3140350_+\|ester-cyclase	unknown	unknown	gnl\|CDD\|377824
NZ_AP018112.1\|WP_096475482.1\|3137942_3138470_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|182018
NZ_AP018112.1\|WP_096475492.1\|3147850_3148315_+\|signal-peptide-protein	unknown	unknown	unknown
NZ_AP018112.1\|WP_096475481.1\|3136925_3137939_-\|FecR-domain-containing-protein	unknown	unknown	gnl\|CDD\|236622
NZ_AP018112.1\|WP_096475720.1\|3142555_3142792_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP018112.1\|WP_096475490.1\|3144630_3145416_+\|3-hydroxybutyrate-dehydrogenase	unknown	unknown	gnl\|CDD\|184025
NZ_AP018112.1\|WP_096475495.1\|3150409_3151333_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182085
NZ_AP018112.1\|WP_096475487.1\|3142818_3143400_-\|undecaprenyl-diphosphatase	unknown	unknown	gnl\|CDD\|183335
NZ_AP018112.1\|WP_096475477.1\|3127630_3127993_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|163507
NZ_AP018112.1\|WP_096475478.1\|3128009_3128354_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|163507
NZ_AP018112.1\|WP_096475480.1\|3132421_3133423_-\|FHA-domain-containing-protein	unknown	unknown	gnl\|CDD\|238017
NZ_AP018112.1\|WP_096475489.1\|3143838_3144579_+\|acetoacetate-decarboxylase	unknown	unknown	gnl\|CDD\|179402
NZ_AP018112.1\|WP_096475493.1\|3148355_3149240_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_AP018112.1\|WP_096475494.1\|3149360_3150299_+\|N-acetyl-gamma-glutamyl-phosphate-reductase	unknown	unknown	gnl\|CDD\|237004
NZ_AP018112.1\|WP_096475485.1\|3140774_3141485_+\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609
NZ_AP018112.1\|WP_096475479.1\|3128387_3132425_-\|TOMM-system-kinase/cyclase-fusion-protein	unknown	unknown	gnl\|CDD\|274846

Protein	Function_ID	Function_description	E-value
NZ_AP018112.1\|WP_047902085.1\|3146568_3147783_+\|patatin-like-phospholipase-family-protein	gnl\|CDD\|132848	cd07209, Pat_hypo_Ecoli_Z1214_like, Hypothetical patatin similar to Z1214 protein of Escherichia coli. Patatin-like phospholipase similar to Z1214 protein of Escherichia coli. This family predominantly consists of bacterial patatin glycoproteins and some representatives from eukaryotes and archaea. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein, but it also has the enzymatic activity of a lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have also been found in vertebrates.	5.15627e-62
NZ_AP018112.1\|WP_096475719.1\|3134068_3136495_-\|TonB-dependent-receptor	gnl\|CDD\|273805	TIGR01783, Ferrienterobactin_receptor, TonB-dependent siderophore receptor. This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	2.31992e-107
NZ_AP018112.1\|WP_096475489.1\|3143838_3144579_+\|acetoacetate-decarboxylase	gnl\|CDD\|179402	PRK02265, PRK02265, acetoacetate decarboxylase; Provisional.	0
NZ_AP018112.1\|WP_096475491.1\|3145429_3146482_-\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	5.13027e-32
NZ_AP018112.1\|WP_096475484.1\|3139900_3140350_+\|ester-cyclase	gnl\|CDD\|377824	pfam07366, SnoaL, SnoaL-like polyketide cyclase. This family includes SnoaL a polyketide cyclase involved in nogalamycin biosynthesis. This family was formerly known as DUF1486. The proteins in this family adopt a distorted alpha-beta barrel fold. Structural data together with site-directed mutagenesis experiments have shown that SnoaL has a different mechanism to that of the classical aldolase for catalyzing intramolecular aldol condensation.	1.04067e-31
NZ_AP018112.1\|WP_096475482.1\|3137942_3138470_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|182018	PRK09651, PRK09651, RNA polymerase sigma factor FecI; Provisional.	3.76866e-43
NZ_AP018112.1\|WP_096475494.1\|3149360_3150299_+\|N-acetyl-gamma-glutamyl-phosphate-reductase	gnl\|CDD\|237004	PRK11863, PRK11863, N-acetyl-gamma-glutamyl-phosphate reductase; Provisional.	0
NZ_AP018112.1\|WP_096475487.1\|3142818_3143400_-\|undecaprenyl-diphosphatase	gnl\|CDD\|183335	PRK11837, PRK11837, undecaprenyl pyrophosphate phosphatase; Provisional.	5.32355e-46
NZ_AP018112.1\|WP_096475495.1\|3150409_3151333_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|182085	PRK09801, PRK09801, LysR family transcriptional regulator.	3.49409e-101
NZ_AP018112.1\|WP_096475490.1\|3144630_3145416_+\|3-hydroxybutyrate-dehydrogenase	gnl\|CDD\|184025	PRK13394, PRK13394, 3-hydroxybutyrate dehydrogenase; Provisional.	2.29478e-164
NZ_AP018112.1\|WP_096475481.1\|3136925_3137939_-\|FecR-domain-containing-protein	gnl\|CDD\|236622	PRK09774, PRK09774, fec operon regulator FecR; Reviewed.	6.18363e-72
NZ_AP018112.1\|WP_096475477.1\|3127630_3127993_-\|hypothetical-protein	gnl\|CDD\|163507	TIGR03795, RNP_Burkhold, ribosomal natural product, two-chain TOMM family. Members of this protein family are found sparsely, mostly in members of the genus Burkholderia. Members often occur as tandem homologous genes, such as BMA_0021 and BMA_0022 in Burkholderia mallei ATCC 23344, or else have a duplication. The genes regularly are encoded near a cyclodehydrogenase/docking protein fusion protein of TOMM (thiazole/oxazole-modified microcins) biosynthetic clusters, suggesting a role in bacteriocin biosynthesis. The role of the putative natural product is unknown, but function as a two-chain bacteriocin is suggested. [Cellular processes, Biosynthesis of natural products].	2.70021e-55
NZ_AP018112.1\|WP_096475478.1\|3128009_3128354_-\|hypothetical-protein	gnl\|CDD\|163507	TIGR03795, RNP_Burkhold, ribosomal natural product, two-chain TOMM family. Members of this protein family are found sparsely, mostly in members of the genus Burkholderia. Members often occur as tandem homologous genes, such as BMA_0021 and BMA_0022 in Burkholderia mallei ATCC 23344, or else have a duplication. The genes regularly are encoded near a cyclodehydrogenase/docking protein fusion protein of TOMM (thiazole/oxazole-modified microcins) biosynthetic clusters, suggesting a role in bacteriocin biosynthesis. The role of the putative natural product is unknown, but function as a two-chain bacteriocin is suggested. [Cellular processes, Biosynthesis of natural products].	1.71457e-49
NZ_AP018112.1\|WP_096475480.1\|3132421_3133423_-\|FHA-domain-containing-protein	gnl\|CDD\|238017	cd00060, FHA, Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins localize to the nucleus, where they participate in establishing or maintaining cell cycle checkpoints, DNA repair, or transcriptional regulation. Members of the FHA family include: Dun1, Rad53, Cds1, Mek1, KAPP(kinase-associated protein phosphatase),and Ki-67 (a human nuclear protein related to cell proliferation).	2.61774e-16
NZ_AP018112.1\|WP_096475493.1\|3148355_3149240_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	3.85919e-40
NZ_AP018112.1\|WP_096475485.1\|3140774_3141485_+\|PadR-family-transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	1.21253e-22
NZ_AP018112.1\|WP_096475479.1\|3128387_3132425_-\|TOMM-system-kinase/cyclase-fusion-protein	gnl\|CDD\|274846	TIGR03903, TOMM_kin_cyc, TOMM system kinase/cyclase fusion protein. This model represents proteins of 1350 in length, in multiple species of Burkholderia, in Acidovorax avenae subsp. citrulli AAC00-1 and Delftia acidovorans SPH-1, and in multiple copies in Sorangium cellulosum, in genomic neighborhoods that include a cyclodehydratase/docking scaffold fusion protein (TIGR03882) and a member of the thiazole/oxazole modified metabolite (TOMM) precursor family TIGR03795. It has a kinase domain in the N-terminal 300 amino acids, followed by a cyclase homology domain, followed by regions without named domain definitions. It is a probable bacteriocin-like metabolite biosynthesis protein. [Cellular processes, Toxin production and resistance].	0

>NZ_AP018112.1|WP_096475485.1|3140774_3141485_+|PadR-family-transcriptional-regulator
MRHNPSRGHDRCDGHGAHARPDWFAGLWYAIGRHRRGHDPFGGGPFGGRGGRGGFGDFGDDGMPRGRQFSSDDLQLLLLALVAEQPSHGYELIKALDTRSNGFYSPSPGMVYPALTYLEEVGFVASQAEGNRKRYALTDAGRAHLDTQRERVDTLFARLTHLARKMEFMRRAFAGESAGNEAQDESQAGWLPEFVEARVALKRALLHKSAAGPDEQRRIAAIMRRATAEIEGGTGA
>NZ_AP018112.1|WP_096475484.1|3139900_3140350_+|ester-cyclase
MSKEDDNKAVVGRWFANFWGEKCDLGIVDEIAAPDMLLKYSLHEPRRGREDIKAFMTDFRAAFPNLNFWGVTDLIAEGDYVVGQWEGGGTHTGPAFSDFLIGSLPAATGRRMHFTGTTVLRLKDGLIVEELGLDDGVTALTQLELIKKA
>NZ_AP018112.1|WP_096475483.1|3138704_3139280_-|hypothetical-protein
MSTDAEPVVVYGDTPGDVATILGALHAQTNIATSEHETRLDRLVACSLDLDEGDALLLEELAGGAHARSIRTPAHFFAALNQAIVELRLSPLFCSSTQGEFHRSICPAAYNERSGEHHPVEMAEWRATFRAMAPEQQMIAATIVWMYRSGADSIWLRRVPCTWQASEALRYMHDAGCLHIWLRLVARFPGW
>NZ_AP018112.1|WP_096475482.1|3137942_3138470_-|sigma-70-family-RNA-polymerase-sigma-factor
MSAAQLAVHQDVQALYRDHHGWLQGWLRRRLGNAFDAADLAQDAFLRLILKPVPKGFDSDAEARAYLRAMAQGMCIDLFRRRQVEQAWLDALAAQPEPCEPSPEYRAIVIETLMEIGVLISRLSDKARGAFVMAQIHGLSTREIAAELGVSDRMVQKYLAQAMLQLALLDAGIKH
>NZ_AP018112.1|WP_096475481.1|3136925_3137939_-|FecR-domain-containing-protein
MAVSSSSSAAESGIQADFESLEQAANWYALLHADGGSGEQRNAWAQWLAERPEHRRAWAHVEAVSRRFEPLRGERKGERNAAAAAVHVSATHSANRRHVLGSLAALSGTGLAGWLAWRFTALPGRLVAWRSDYRTGVGERRDVQLADGTRVWLNTDSAFDVHYDDTRRLLTLAMGEILIDTARDSQGRPFFVDTPNGRMQALGTRFTVRQSGTNTLLAVFNGRVEIRNLAGHVEIVPAGQQRQFTADAISNPERADPAREAWSRGVILADDVTLDTLIAELDRYQRVHIGVDPSVAGIRVVGRFPADDPDRMLAMLERDLPIRVHRTLPWWVTIDAR
>NZ_AP018112.1|WP_096475719.1|3134068_3136495_-|TonB-dependent-receptor
MRTAHRPAAHAVRCAVLGIALAGSGAWQAASAQSAAGAAAQAAPRRYDIPAGPLSASLNRLADQANVLLSVPGDLTAGKTSAGVHGTYSVQGAFQALLNGTGLEPVRQSDGSFSLRPVAAAAGAEAAVLPAVKVLGKRIDDAVPEPYAGGQVAQGAKVGMLGNRDYMDTPFSISSYTEKLIRDQQSTSVADLLTTTDPSVRAAIDSTNRYDAITIRGLRVENSEIALNGLYGLVPAYRVGADPVERVEILKGPGALLNGMMPQGSVGGSVNVVTKRADDTPLNRLTAEYASSSVFGGHADIGRRFGQNGEFGVRVNAAHREGDTPIDEQSRRNTSLSVGLDYRGSRLSVSGDVIYQEDFMRAPVRGYTPIAGIAVPQAPDSRTNLAQTFSYSNSHSLTALGRAEYDLSSNVTLFGAVGMNRFGYDKLEDPGATIVNAQGDAKSTSRYQSGASHALSAEAGARARFKTGPIDHQLVVSGDYLQQTTWFGQTAYGSYATNIYMPTRLAGPGAPVSVSPEAKDSAQILRSIGVADTLSAAGGLVQLTVGVRRQQVSSRNFDTSGAETSHYDQGATTPSVALVVRPLDQLSFYANYIEALTPGSAPPPDAANPNQVFAPFKSKQYEVGTKLDLGKFGATLGLFQIDVPSGIVDPVSKLFSLNGLQRNRGLELSGFGEVTRGVRLLGGVTWLDARLRRTQGGTYDGNRAIGAPSLQATLGAEWDTPFVPGVTLTSRMIYTGKAYVSQDNTQHVPSWTRFDLGGRYTTKVAGRDVTLRANVTNLFNRDYWQANPTGYLFTGAPRTFWLSVSTDL
>NZ_AP018112.1|WP_096475480.1|3132421_3133423_-|FHA-domain-containing-protein
MAILKNDSSGEACLLRAYHVFGRDAARCDTVIRDASVSRVHAHIRWIGGQWELHDHSSNGTSVSGVPLRDGEHAVLRPGDVIRFGRAGIAPWRVDALDDPADTLWPIRGAAHPIVLAPSQILAARAAQPVTIVRSPAGEWLCDDTLPPRALHDGDEVSTGDVTWRLALVRNGSTMMLAAPADPAAPAQLLEFFVSRNEEHVRMLLHVRGGVVDLGERAHHYSLVTLARARSADMQAGYDAASQGWIELDRLARMLGIDTSHVNVQIHRARNQFAAVPGLDASQLVERRRGSVRFGDFPFRVMRGEHLECQSVPGVQPRIGVHRPAPDPVVHYS
>NZ_AP018112.1|WP_096475479.1|3128387_3132425_-|TOMM-system-kinase/cyclase-fusion-protein
MNTGEPAVLPIASRAPVVPEALELRQSAAPFAELAGKWHYRLGSQLGEGGNGVVFRATCGETGQDVAIKLMRDDAARTATERARQRARFRRETSLCEALRHPNIVALLDKGEAPDGRLFAVFELVQGRTLRDRLAAQGPLSAVDTGRLMTEVLDGLAAAHRRGIVHRDLKPQNIVITMADDGPHAKLLDFGIGALLPGTEDIARETSTLATEVLGSPPYCAPEQLRNELPTPRSDLYAWGLVVIECLTGDVVMRGASVADILYQQLSPVDVALPPSIASHPLGSVLRRALNKNPEQRAASADELAETFRTLNFAALVGQFDAGRASGQTRPRPFAPRGETIATAGEYRQITTLCCCVAITGTGRQRHAGTDHGDLLDGYEEQWLTKCADIAVGYGAQVDGRLGDTLLFHFGLRGDIDRPARRAARAALDMVRLAERARLPAAAGGHAGAESWRVEVAAAIHVGQVLTHASRMSGVSTPAAAARLLRLAGPGQILISDDARLALERHADYRPTSLRLARAGLVPQPVHELLGERRADTPFDSLDAGMRVPMVGRARELDALLRAWQETLARHRRVMRGEPAPHGVPRLVVGDAGIGKSRLVHELCEAVRIQGHAFAHCGCLPERENHALFPILRFIGAHWHIGADSPAGFALAAIDAMIAPLECDHAAARVALATWLGLPCDAKGFLWSSERELHALFDVLKQLIVSLGNGAPVLLVVEDVQWIDRSTEDFLAYLQRSPRAAALGIVFTSRPDKLGRWRGATERLVLRRLPRDDAQRLMSACLGQGALDPAWLDQLAQRTSGIPLFIEAVARELTMSGADGSLAGLRDTDPDPLPLSLGGMLGLAFDRIDDARDTAQLAATIGLEVDARLLADASPHDRATLDAHLQLLLEERIVYAQHRRDRVFYSFRHALIRDAAYESMPPAVRRGNHARVGRALAAEVDRGAGAHAFGVAGHFARADAFADAIAHGIDAARRALERSRYDDAIRYGQSVFDWLGNADHAQREHDSARIRATLTHATMARFGWADPQVREHAEQLLRQMQTLDDPELEISALWTLSTYYHVAGDRPTVRGIGMRLDALATERGDAGVQVAADAMRGMSLWVDGDYTRARAAFDAVLAGYDVRRDAGHRRLLGLDTRAWTMASLASVRWCMDDDPQASLALARDAVYCATCLDHLPTLGVTMMYLARTHQLAGDRDAARTLSEAILRLSEVHRLRAVGHYAAIIHAWTQGDRAGVVEHLDAQRQSGGLLGLTYYASLLAELDAERGDYPAALARIEQCLAWCESTGERYYEAQLLLKKCEYLRQADPRCGGVAALAACRRACEVATTAGMGRIARLAGAMLQSLP
>NZ_AP018112.1|WP_096475478.1|3128009_3128354_-|hypothetical-protein
MSKDLRLPTYEQFLEYRATVIRAIALAWHSPAFLDELEADPVQALREHFGYHFPFKLDLKVQTKSSAWTPSVNGDWTAGQKNKLTLFLPPAPANEAQFAQALAAYNANHITIME
>NZ_AP018112.1|WP_096475477.1|3127630_3127993_-|hypothetical-protein
MAKDNANPTLESMLEFQKVYLRAIALSWRNPEFKDELLEKPLETLAKYFGYQCPWIIDIEVVKTHGDHGWTSDGNGSGSWNLPRNVMTVGIPEQPTDLDEEAVALAAYCDAGPSYLFTCC
>NZ_AP018112.1|WP_096475720.1|3142555_3142792_+|hypothetical-protein
MTKESHASPFLRNLKIAGYCGLAAVVLALFVAMCAILKESALDRDAAQHPADTPELHDAGGGPSASAESSARTPGSPG
>NZ_AP018112.1|WP_096475487.1|3142818_3143400_-|undecaprenyl-diphosphatase
MQNLNLALFSAINAGHAPQPGVVRLAIFAADWLVYALPAMLLLTWIFGARPTRRQAIEAGVGVCVALVLAQVIGHFWFSPRPFMAGVGTQLIPHAPDSSFPSDHMTFAWSMAVGLMLGGTTRLTGYVMAAMAVAIAWGRIYAGVHWPFDMAGGVLVGTAGALAAHLYGQRVTALLERLGDSVHAVVMGRRHAP
>NZ_AP018112.1|WP_096475489.1|3143838_3144579_+|acetoacetate-decarboxylase
MKPSDVRSKAFAMPLTSPAFPMGPYRFVDREFLIITYRTDPDRLREIVPEPLQVTEPLVHYEFIRMADSTGFGDYTESGQVIPVEYNGQPGGYTLAMYLDDHPPIAGGRELWGFPKKLASPTLHVNTDHLLGTLDYGKVRVATGTMGYKHKELDIAEQTRRLAGPNFLLKIIPHVDGTARVCELVRYYMQDIKMKGAWTGPASLELAPHALAPVADLPVLEIVEARHIVADLTLGLGEVVYDYLAQ
>NZ_AP018112.1|WP_096475490.1|3144630_3145416_+|3-hydroxybutyrate-dehydrogenase
MSNLNGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEINKAGGKAIGVAMDVTNEEAVNSGIDKVAETFGSVDILVSNAGIQIVNPIENYAFSDWKKMQAIHVDGAFLTTKAALKHMYKDDRGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARVLAKEGAKHNVRSHVVCPGFVRTPLVDKQIPEQAKELGISEEEVVKKVMLGNTVDGVFTTVQDVAQTVLFLSAFPSAALTGQSFVVSHGWFMQ
>NZ_AP018112.1|WP_096475491.1|3145429_3146482_-|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MILVYRYRVKSLNGLLNKQSRAVNYVWNFCNDTQKHTLKWNKKWPTGFDLNVLTTGSSKELGIHSGTVNATCEQYAKSRNQHRRAYLRYRGRKSLGWVPLKGRDLKREGDAFRFAGNTFRVFSSRPLPEGKIKDGTCFAQDARGNWFLNIVIEMPNAQARPIRSGVGIDLGLKDFATLSTGEKLPNDRFGRRAAEKLAKAQRARKHKRHIAKLHAKVANARADFQHKLALALVRRFDYIAVGNVSATKLARTRMAKSIYDASWSSFRNKLRYKAMAHGVTFEEVDESGSTQSCSACGSRDSTTRPRGIAGLRIREWACSDCGVVHDRDTNAALNILRCGRASPGVGIASL
>NZ_AP018112.1|WP_047902085.1|3146568_3147783_+|patatin-like-phospholipase-family-protein
MKPHARTEKQAVDETDLHEAGAPTAARSLPYETIALVLQGGGALGAYQAGVFEGLHEAGIPLDWIAGISIGALNTALIAGNAPEHRVERLREFWETICQPAFFPAIPAAFEFALFNSIDQIRTFFTASQAASAMMQGQQGFFSPRFPPPLPGVSDHPEKISWYDTSALRTTLLKLCDFDRINSGETRISVGAVNVGTGNFVYFDNSRIRLAPEHFMASGALPPAFPPVEIDGEYYWDGGVVSNTPLMEVLRARPRRDTLAFQVDLWSARGPLPRTMADVAERTKDVQYSSRTRFVTDTLQREQRYRNVLRHVLEQVPEEQRKNDPWCVEADAMSSGKKYNIQHLIYQQKAYEHHYKDYQFGLSTMRDHWSAGLDDIRKTLAVKDGLALPNNDAGFVTHDIHRRR
>NZ_AP018112.1|WP_096475492.1|3147850_3148315_+|signal-peptide-protein
MPIFIALFALIAMGWGAVHLFHVIAAQFGQPVAIAAAVLAAAILIALVAWWIKRRRDIAPNTKEEGWTHVVHRAWGELRLSATQGLLWLSHDGADGRYTLSQLDGCQAAPIGGRWHLVVRVRDAVRSEWKLPMTDKRDAQRWARVLMLAKDNRL
>NZ_AP018112.1|WP_096475493.1|3148355_3149240_-|LysR-family-transcriptional-regulator
MREISLDRLRTLVAIADQGSFVAAAQLLHLAPPTVSLHVAELESRVGAPLLSRTRGNVRPSAIGEVLVERARSLLAEVEATLDDVQRQVQGLTGRVRLGASTGAIAHLLPQAVARLREQHPDIDVQIAVLTSHDTLARIAQGTLDVGLVALPQAPVAGLSIRAWRRDPVMAFLPADWRLPARVTPAYLAARPLILNDATTRLSRLTTEWFALGGHRPEPRIELNYNDAIKSLVAAGYGATLLPHEAGAPLPDARVVMRALRPALWRELGIAHRARPVERATQHVLDALWALGAR
>NZ_AP018112.1|WP_096475494.1|3149360_3150299_+|N-acetyl-gamma-glutamyl-phosphate-reductase
MSFPTVYIDGDQGTTGLQIHERLRERTDLRLVTLPDAERKDPVRRAEAINACDIAILCLPDAAAREAVGFIRNPEVRVIDASSAHRTEPEWVYGFPEMVDGHAQKIAHARRVTNPGCYPTGAIGLLRPLQQAGLLPRDYPVSIHAVSGYSGGGRTAIDAFESHGATHAKPLQVYGLALAHKHVPEIQQHAGLAHRPLFVPAYGAYRQGIVLTVPIELRLLPAGVTGEQLHACLAHHYASARHVDVTPLADARAITHLDPQALNGTNDLRLGVFVNADHGQVLLAAVFDNLGKGASGAAVQNLDLMLGASSAV
>NZ_AP018112.1|WP_096475495.1|3150409_3151333_-|LysR-family-transcriptional-regulator
MNKSPNLDDLRVFSLVVRLTSFSAAAEQLAVSPAYVSKRIALLEAQLGTRLLHRSTRRVTVTEAGERVFARAEKILDDVDHLVEDVSTTRTVPRGTLRISSSFGFGRHVVAPALLDFSARYPQLNVRLDLFDRLVDVAGEGYDLDVRIGDEIADHLIARRIAANYRVLCASPDYLARRGTPRSLADLASHDCLAIKERDHPFGVWRLNVRGETATVKVGGALSTNHGEVAVQWALAGRGIVLRSIWEAGPLIERGALCRVLPDAIQPANIWAVYPERVAASAKVRVCVDFLVETLAGLNAAAGDDTA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1552750 : 1586929

Staphylococcus_phage(25.0%)

plate,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080435171.1\|1552750_1554127_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.1e-31	34.2
WP_096470968.1\|1555561_1557052_-\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_157776408.1\|1557867_1558434_-	hypothetical protein	NA	NA	NA	NA
WP_096474355.1\|1558502_1563410_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_096474356.1\|1563406_1564705_-	hypothetical protein	NA	NA	NA	NA
WP_096474357.1\|1564722_1565346_-	hypothetical protein	NA	NA	NA	NA
WP_096474358.1\|1565400_1567674_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	4.9e-45	28.9
WP_096474359.1\|1567670_1570337_-	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	8.8e-78	29.3
WP_096474360.1\|1570349_1571471_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_096474361.1\|1571467_1573339_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_096474362.1\|1573343_1573892_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_072436815.1\|1573918_1574410_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_096474363.1\|1574469_1575978_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_096475619.1\|1575970_1576525_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_096474364.1\|1576622_1577738_-	type VI secretion system protein TssA	NA	NA	NA	NA
WP_096474365.1\|1577724_1579797_-	serine/threonine protein kinase	S4VYW6	Pandoravirus	3.1e-06	26.3
WP_096474366.1\|1579858_1580554_-	type VI secretion system-associated protein TagF	NA	NA	NA	NA
WP_096474367.1\|1580535_1584162_-	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_096474368.1\|1584163_1585498_-	DotU family type VI secretion system protein	NA	NA	NA	NA
WP_096474369.1\|1585513_1586929_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_AP018111

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_AP018111_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP018111_1

494103-494182

Orphan

Consensus_repeat	Method
GCACGGTGACGGTCGAACCGTGTTCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP018111_1

>merge|NZ_AP018111|1|494103-494182|CRISPRCasFinder
GCACGGTGACGGTCGAACCGTGTTCGCGACCCATGCCTCATGCCGATCTGCGAGCACGGTGACGGTCGAACAGTGTTCGC

>NZ_AP018111|1|1|494103-494182|CRISPRCasFinder
GCACGGTGACGGTCGAACCGTGTTCGC	GACCCATGCCTCATGCCGATCTGCGA
GCACGGTGACGGTCGAACAGTGTTCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP018111.1\|WP_096470923.1\|493338_494067_+\|precorrin-4-C(11)-methyltransferase	unknown	unknown	gnl\|CDD\|225430
NZ_AP018111.1\|WP_096470927.1\|501642_502560_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|238182
NZ_AP018111.1\|WP_096470922.1\|492563_493295_+\|cobalt-precorrin-6A-reductase	unknown	unknown	gnl\|CDD\|236144
NZ_AP018111.1\|WP_096470920.1\|490225_491479_+\|precorrin-6y-C5,15-methyltransferase-(decarboxylating)-subunit-CbiE	unknown	unknown	gnl\|CDD\|225151
NZ_AP018111.1\|WP_096470925.1\|497237_498362_-\|porin	unknown	unknown	gnl\|CDD\|238208
NZ_AP018111.1\|WP_096470929.1\|503569_504418_+\|TauD/TfdA-family-dioxygenase	unknown	unknown	gnl\|CDD\|181947
NZ_AP018111.1\|WP_047900679.1\|496333_497038_-\|glutathione-S-transferase-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|183298
NZ_AP018111.1\|WP_096470928.1\|502578_503559_+\|quinone-oxidoreductase	unknown	unknown	gnl\|CDD\|176189
NZ_AP018111.1\|WP_096470916.1\|484076_485279_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340882
NZ_AP018111.1\|WP_096470917.1\|485285_487001_-\|precorrin-3B-C(17)-methyltransferase	unknown	unknown	gnl\|CDD\|381173
NZ_AP018111.1\|WP_157776323.1\|494194_494353_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP018111.1\|WP_047900671.1\|486997_487732_-\|precorrin-2-C(20)-methyltransferase	unknown	unknown	gnl\|CDD\|180341
NZ_AP018111.1\|WP_096473013.1\|494368_495547_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340968
NZ_AP018111.1\|WP_096470924.1\|495676_496201_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_AP018111.1\|WP_096470915.1\|483079_483982_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182183
NZ_AP018111.1\|WP_096470919.1\|488347_489835_-\|precorrin-3B-synthase	unknown	unknown	gnl\|CDD\|274131
NZ_AP018111.1\|WP_096470918.1\|487728_488355_-\|precorrin-8X-methylmutase	unknown	unknown	gnl\|CDD\|181352
NZ_AP018111.1\|WP_047900685.1\|504551_505607_+\|3-keto-5-aminohexanoate-cleavage-protein	unknown	unknown	gnl\|CDD\|377562
NZ_AP018111.1\|WP_096470921.1\|491478_492567_+\|cobalt-precorrin-5B-(C(1))-methyltransferase	unknown	unknown	gnl\|CDD\|234615
NZ_AP018111.1\|WP_096470926.1\|498715_501400_-\|LuxR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225461

Protein	Function_ID	Function_description	E-value
NZ_AP018111.1\|WP_096470923.1\|493338_494067_+\|precorrin-4-C(11)-methyltransferase	gnl\|CDD\|225430	COG2875, CobM, Precorrin-4 methylase [Coenzyme metabolism].	1.025e-127
NZ_AP018111.1\|WP_096470922.1\|492563_493295_+\|cobalt-precorrin-6A-reductase	gnl\|CDD\|236144	PRK08057, PRK08057, cobalt-precorrin-6x reductase; Reviewed.	1.27813e-118
NZ_AP018111.1\|WP_096470920.1\|490225_491479_+\|precorrin-6y-C5,15-methyltransferase-(decarboxylating)-subunit-CbiE	gnl\|CDD\|225151	COG2242, CobL, Precorrin-6B methylase 2 [Coenzyme metabolism].	1.55156e-73
NZ_AP018111.1\|WP_096470925.1\|497237_498362_-\|porin	gnl\|CDD\|238208	cd00342, gram_neg_porins, Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers are stabilized by hytrophillic clamping of Loop L2. Loop 3 bends into the pore, creating an elliptical constriction of about 7 x 11A, large enough to allow passage of a glucose molecule without steric hindrance. Removal of the C-terminal residue (usuallly F) destabilizes the trimer and removal of the 16th beta-sheet abolishes trimerization. Unlike typical membrane proteins, porins lack long hydrophobic stretches. Short turns are found at the smooth, periplasmic end, longer irregular loops are found at the rough, extracellular end. C-terminal residue forms salt bridge with N-terminus.	6.13296e-65
NZ_AP018111.1\|WP_096470929.1\|503569_504418_+\|TauD/TfdA-family-dioxygenase	gnl\|CDD\|181947	PRK09553, tauD, taurine dioxygenase; Reviewed.	2.85482e-78
NZ_AP018111.1\|WP_047900679.1\|496333_497038_-\|glutathione-S-transferase-N-terminal-domain-containing-protein	gnl\|CDD\|183298	PRK11752, PRK11752, putative S-transferase; Provisional.	8.63555e-73
NZ_AP018111.1\|WP_096470928.1\|502578_503559_+\|quinone-oxidoreductase	gnl\|CDD\|176189	cd05286, QOR2, Quinone oxidoreductase (QOR). Quinone oxidoreductase (QOR) and 2-haloacrylate reductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. 2-haloacrylate reductase, a member of this subgroup, catalyzes the NADPH-dependent reduction of a carbon-carbon double bond in organohalogen compounds. Although similar to QOR, Burkholderia 2-haloacrylate reductase does not act on the quinones 1,4-benzoquinone and 1,4-naphthoquinone. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	0
NZ_AP018111.1\|WP_096470916.1\|484076_485279_+\|MFS-transporter	gnl\|CDD\|340882	cd17324, MFS_NepI_like, Purine ribonucleoside efflux pump NepI and similar transporters of the Major Facilitator Superfamily. This family is composed of purine efflux pumps such as Escherichia coli NepI and Bacillus subtilis PbuE, sugar efflux transporters such as Corynebacterium glutamicum arabinose efflux permease, multidrug resistance (MDR) transporters such as Streptomyces lividans chloramphenicol resistance protein (CmlR), and similar proteins. NepI and PbuE are involved in the efflux of purine ribonucleosides such as guanosine, adenosine and inosine, as well as purine bases like guanine, adenine, and hypoxanthine, and purine base analogs. They play a role in the maintenance of cellular purine base pools, as well as in protecting the cells and conferring resistance against toxic purine base analogs such as 6-mercaptopurine. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The NepI-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.81094e-49
NZ_AP018111.1\|WP_096470917.1\|485285_487001_-\|precorrin-3B-C(17)-methyltransferase	gnl\|CDD\|381173	cd11646, Precorrin_3B_C17_MT, Precorrin-3B C(17)-methyltransferase (also named CobJ or CbiH). Precorrin-3B C(17)-methyltransferase participates in the pathway toward the biosynthesis of cobalamin (vitamin B12). There are two distinct cobalamin biosynthetic pathways. The aerobic pathway requires oxygen, and cobalt is inserted late in the pathway; the anaerobic pathway does not require oxygen, and cobalt insertion is the first committed step towards cobalamin synthesis. This model includes CobJ of the aerobic pathway and CbiH of the anaerobic pathway, both as stand-alone enzymes and when CobJ or CbiH form part of bifunctional enzymes, such as in Mycobacterium tuberculosis CobIJ where CobJ fuses with a precorrin-2 C(20)-methyltransferase domain, or Bacillus megaterium CbiH60, where CbiH is fused to a nitrite and sulfite reductase-like domain. In the aerobic pathway, once CobG has generated precorrin-3b, CobJ catalyzes the methylation of precorrin-3b at C-17 to form precorrin-4 (the extruded methylated C-20 fragment is left attached as an acyl group at C-1). In the corresponding anaerobic pathway, CbiH carries out this ring contraction, using cobalt-precorrin-3b as a substrate to generate a tetramethylated delta-lactone.	8.40221e-121
NZ_AP018111.1\|WP_096470921.1\|491478_492567_+\|cobalt-precorrin-5B-(C(1))-methyltransferase	gnl\|CDD\|234615	PRK00075, cbiD, cobalt-precorrin-6A synthase; Reviewed.	1.24804e-171
NZ_AP018111.1\|WP_047900671.1\|486997_487732_-\|precorrin-2-C(20)-methyltransferase	gnl\|CDD\|180341	PRK05990, PRK05990, precorrin-2 C(20)-methyltransferase; Reviewed.	8.88964e-173
NZ_AP018111.1\|WP_096473013.1\|494368_495547_-\|MFS-transporter	gnl\|CDD\|340968	cd17410, MFS_CynX_like, Cyanate transport protein CynX and similar proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of Escherichia coli cyanate transport protein CynX and similar proteins. CynX is part of an active transport system that transports exogenous cyanate into E. coli cells. The gene encoding CynX is part of the cyn operon that also includes cynS, encoding cynase, which catalyzes the reaction of cyanate with bicarbonate to give ammonia and carbon dioxide, and cynT, which encodes a carbonic anhydrase. The CynX-like subfamily belongs to the 2-nitroimidazole and cyanate transporters like (NIMT/CynX-like) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.57116e-81
NZ_AP018111.1\|WP_096470924.1\|495676_496201_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	7.72192e-20
NZ_AP018111.1\|WP_096470915.1\|483079_483982_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|182183	PRK09986, PRK09986, LysR family transcriptional regulator.	1.41474e-57
NZ_AP018111.1\|WP_096470919.1\|488347_489835_-\|precorrin-3B-synthase	gnl\|CDD\|274131	TIGR02435, Precorrin-3B_synthase, precorrin-3B synthase. An iron-sulfur protein. An oxygen atom from dioxygen is incorporated into the macrocycle at C-20. In the aerobic cobalamin biosythesis pathway, four enzymes are involved in the conversion of precorrin-3A to precorrin-6A. The first of the four steps is carried out by EC 1.14.13.83, precorrin-3B synthase (CobG), yielding precorrin-3B as the product. This is followed by three methylation reactions, which introduce a methyl group at C-17 (CobJ; EC 2.1.1.131), C-11 (CobM; EC 2.1.1.133) and C-1 (CobF; EC 2.1.1.152) of the macrocycle, giving rise to precorrin-4, precorrin-5 and precorrin-6A, respectively. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin].	2.39337e-75
NZ_AP018111.1\|WP_096470918.1\|487728_488355_-\|precorrin-8X-methylmutase	gnl\|CDD\|181352	PRK08285, cobH, precorrin-8X methylmutase; Reviewed.	1.85385e-136
NZ_AP018111.1\|WP_047900685.1\|504551_505607_+\|3-keto-5-aminohexanoate-cleavage-protein	gnl\|CDD\|377562	pfam05853, BKACE, beta-keto acid cleavage enzyme. BKACE, beta-keto acid cleavage enzyme plays, a role in lysine degradation. In certain instances it catalyzes the conversion of 3-keto-5-aminohexanoate and acetyl-CoA into acetoacetate and 3-aminobutyryl-CoA. The family is found to have at least 14 slightly different potential new enzymatic activities, all of which can therefore be designated as beta-keto acid cleavage enzymes.	2.76605e-79
NZ_AP018111.1\|WP_096470927.1\|501642_502560_+\|universal-stress-protein	gnl\|CDD\|238182	cd00293, USP_Like, Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae Usp reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, athough Usp lacks ATP-binding activity.	0.00225288
NZ_AP018111.1\|WP_096470926.1\|498715_501400_-\|LuxR-family-transcriptional-regulator	gnl\|CDD\|225461	COG2909, MalT, ATP-dependent transcriptional regulator [Transcription].	1.51926e-72

>NZ_AP018111.1|WP_096470923.1|493338_494067_+|precorrin-4-C(11)-methyltransferase
MTVYFIGAGPGDPELITVKGQRLVRTCPVILYAGSLVPAAVLDGHRAEQVVNTAELDLDAIVALLAAAHAKGQDVARVHSGDPSLYGAIGEQIRRLKVLGIPYEIVPGVTATAACAATLGVELTLPGVAQTVILTRFAGKTTMPEGEALGSLAAHRATLAIHLGVRHLARIVDEVLPHYGADCPVAVIYRASWPDEERVTGTLADIVGKVQGTQIERTALILIGRVLDAEGFADSTLYASAG
>NZ_AP018111.1|WP_096470922.1|492563_493295_+|cobalt-precorrin-6A-reductase
MSARILLLGGTGDALKIARALGPHHVYSLAGLGKVPDDLRCDVRVGGFGGAAGLAAYLRSAGIGLVIDATHPYAAQISANAAAATRDAGVPLWALRRAPWAPQPGDDWRMVDDWAGIEAALAPFRRPLFTLGREPLAHLDAIPAHQFWLVRCLDAHPGNPHAQIVAARGPFTLDGERALFALMGIDVVVSKNSGGAATEAKLDVARERKLPVVMLRRPPLPDADRAFDSAAALLDALDPAARV
>NZ_AP018111.1|WP_096470921.1|491478_492567_+|cobalt-precorrin-5B-(C(1))-methyltransferase
MRDETPEQHAPLRFGYTTGSCATATSLAAARLLLAGHADDAVEIVLPKGQRVMMRLEFCRITADGAEAGTIKDAGDDPDVTHGALIFARVALAAAPGVRFHAGPGVGTVTRAGLTLAVGEPAINPVPRQMMTTHLDALAAEHGYAGGFDVTIGVEDGEALALKTMNPRLGIVGGLSILGTTGIVRPFSCSAYIASIHQGIDVARANGIEHIAACTGNTSEDAMRAHYHLPDMALVEMGDFAGAVLKHLRRAPVARLSMCGGFGKLSKLAAGHLDLHSRHSSIDLPLLAQWAAEAGASDALQAAMRAANTSQEALKLALADGVPLGDLVCAQALRVARDIVPPSVAVEMFAIDRQGRFVGQAR
>NZ_AP018111.1|WP_096470920.1|490225_491479_+|precorrin-6y-C5,15-methyltransferase-(decarboxylating)-subunit-CbiE
MTAWLTVVGIGDDGYAGLGRSARRALLDATLVVGAQRHLDMLPARLPAARETWPSPFDIAGVLARRPSPVCVLASGDPMLFGVGATLARQLSPDEWRVLPAPSSLSLAAARLGWALQDIGAVSLVGRPLATLARHLLPGRRLFVLSADGRTPAAVAAELAARGFGPTRISVFEHLGGPLERRVDGLAQDWNVDETAALNLVALDCQAGPDAPRRALTPGLPDDAYRHDGQLTKRDLRAMTLGRLAPAPGELLWDVGAGSGSIGIEWMRAHPSCQAIAIEAHAERQRFIEHNRDALGVPGLQLVAGRAPDALAGLAAPDAVFIGGGATAPGVLDACWSSLKPGGRLVANAVTLQGEMALAAWRDAHGGTLTRVSLAHAEPLGRFDTWRQPLPVTLYDVRKPDAAATAGPSNLTNATDA
>NZ_AP018111.1|WP_096470919.1|488347_489835_-|precorrin-3B-synthase
MRASRRRAGCTDALAAARHCPGTPLSSAPDSIPASPVVRPSACPGLMRVVAAADGGLCRIKLPGGRLDAREARAIAAAARAYGSGAVDATNRANLQLRGIRDGAADALTRALLDAGLGPRADATAKSTADATADAAVLAASDDVRNVLLSPLAGHDPAALVDSRALAVPLLDMLASEPRRGELSPKFSIQLDGGESVAALDHPHDIWLAAWRRDDGTVRIAAGLAGCPPTAFDDTPASVDVSPGQSVALVRALLLAFLDLAPADVTRMRALLATCGERALLERAQHYLPFPLAADPALAGWRRTRSDSALRFGARPSLDAARCSVGAQFALGRLDATQLERLAALADADGDGSLSMTPWQGVFIHGVSHARAPAMLDALASLGLVCTSSDPLATLVACTGSAGCAKAHADTKHDARALAARIGHPVDVHLTGCERHCALPHPAAHTLVAVAPAHYDLYRRDAAAGLGAPLARHLTIDQAAARLTGTRHSQDTTDA
>NZ_AP018111.1|WP_096470918.1|487728_488355_-|precorrin-8X-methylmutase
MLDYIRDGQEIYRQSFATIRAEADLSQVPPDLEKLAVRVIHACGMVDVVYDLRFSAGAGTAGRTALAAGAPILCDAKMVAEGITRARLPAGNPVICTLGEPEVPDLARHLGNTRSAAALELWRPHLAGSVVVIGNAPTALFHLLDMIDAGAPRPALILGFPVGFIGAAESKAMLDADSRGVPYVALLGRRGGSAMAAAAVNALATEVE
>NZ_AP018111.1|WP_047900671.1|486997_487732_-|precorrin-2-C(20)-methyltransferase
MTTARGRLFGVGVGPGDPELMTIKALRVLQAAPVVAYFVAKGKKGNAYGIVEAHLLDTQTQLPLVYPVTTEALPPPLCYETVIADFYDTAAEIVAAHLDAGRDVAVICEGDPFFYGSYMYLHDRLAPRYDTEVIPGVCSMLGGTAVLGQPLVYRNQSLSVLSGVLPEHELRARLAQADAAVVMKLGRNFDKVRRVLDELGLAKRALYVERATMASQRIVPLDEVDPMASPYFSLLVVPGEKWQG
>NZ_AP018111.1|WP_096470917.1|485285_487001_-|precorrin-3B-C(17)-methyltransferase
MTTPPAIVILGAGALDTARRIQARYPGARVHGLAARVDADEPFDELGAHLRELYARGLPIVALCAAGIVIRCLAPALADKGVEPPVLAVAEDGSAVVPLLGGLTGVNVIARELAEWLGVAPAITTSGELRFGACVLNPPEGYALADLAQGKRFVSDLLAGAPTRIDGAAPWLDDVALPRDDAAAHAIRVTPDAWRGTQDELVIHPRSVVVGVDAHAVHADDALAARIEAALDAQGLARLALAAIVAPVSAIGEAVLEDAAQTLGAPLRFVDVEVDPHAQTDAATLLGRALRVAHTLRAASNGLACAVASHPVDPATLGRARGRLTVLGLGPGGAAWLTPAARAALAQATDILGYTTYVNMAGPFRADQRVHGTDNREEMQRARHAFELAAEGRRVAVVSSGDPGVFAMAAAVLEALDEARDPQWAKVDLRVEPGISASLATAAQAGAPLGHDFCAISLSDNLKPWDVIETRLRHAAQADLVMAFYNPISRARPWQLDRALDVVRAHRAADTVVVLGRDIGRPGATLATTTLGALRSDQVDMRTMVIVGSSTTRRFAIDGGREWVYTPRWYR
>NZ_AP018111.1|WP_096470916.1|484076_485279_+|MFS-transporter
MNDRITRIAFFLCGFAAFLNLYSTQGILHELAATFGVSAERAGQGVSATTTAVAIIAPFVGMLAARIERRIAISLAAVAVALPVVWSAHAASFASFLGARFAAGLLMPFIFALSIAYIGERFDRGTSAEIGALFVAGTTLGGFAGRFATNLLTSMWGWRHALDIVAALCLVTGVAIYASLPAAGAIARRSGHDADAEPSSRIVTRGPLLASFAIGACVLASQVATFTFVGLRLARAPFSFGTVEIGAIYAVFLVAVVVTPLAGRLARHRGPRAPGLAAAAFAIGGALLTLSDSVPVILAGLALSSTAVFVEQASANAFISQAASTARSTAIGIYLSCYYFGGSLGSILPVPGWHRWGWAGCVAFVVVAQAIVGVLVYRFWRTGSAAGTGHADVRGARFMR
>NZ_AP018111.1|WP_096470915.1|483079_483982_-|LysR-family-transcriptional-regulator
MLDLRRLRYFVVVADELHFGRAALRLRVAQPPLTRHIAALESELGVRLFERSTRAVRLTPEGALFLEHARNVVSAAAEAETSARKIAQGIAGRIVIGYASSIPMSDTFPDVIRAASRTMPDVELAFREAATASQRQQIADGTMDIGFGWAWDGAPGVAVASLVASREPLVAAVPAGNALAGRASVDVAELADETFVTFPPGYGSAFTAALDDLCAQAGFAPRIGATAAQITTLVSLVAAERGIAIVPGFTATLQRPGVVYVPLAGARSVEQIVSWSEPFASACVERFVALARSLVQPASA
>NZ_AP018111.1|WP_157776323.1|494194_494353_+|hypothetical-protein
MPICEQLIGALGDDVQNAIRVCRLCDEDACDLRRCPSERAYRRLLAERDATN
>NZ_AP018111.1|WP_096473013.1|494368_495547_-|MFS-transporter
MNRFTSPGWRLAAIVLVGLNLRPALAAVGPLLDMIQRATGIGDGAASLLTTIPILLMGLGALSARRLQRVTGIAGGVWLGVALIGLACVSRIGAQHAWLLLASACCAGVGIAMVQALLPGFVKAHFATRVGGAMGVYSTSIMGGAVLASVVAPFAAARWGWLAALAGWALPAAVAALAWPLASRGGDALAAGPASASTAQPSRSPRAWRLALFFGIATGAYTLVLAWLPPYYMRLGWSPTAAGSLLGGVTLAEVVAGLTISATIDRLPDRRPALHAAIASLFAGLLVMLAAPEALALPAALLLGAGIGALFPLSLIVTVDHAATPADAASLTGFVQGVGYLIAGLFPFAAGVVRQHLADLTPAWVAMACLCVVLFALAAGFAPRLARRVASA
>NZ_AP018111.1|WP_096470924.1|495676_496201_+|MarR-family-transcriptional-regulator
MDRAAHALAQWRAERPDLDASSMVVMGRLQEAALVIARDRLNPLFARYGMQPGEFDVLATLRRGGAPFALTPTALYDALMMSSGGMTARIDRLQKAGWVERRPNPADGRGTLVALTETGRALIDEAVVAHIDNQRALLAALSDAEQAQLSQLLGKLLAGLADGAPERPEAPGGK
>NZ_AP018111.1|WP_047900679.1|496333_497038_-|glutathione-S-transferase-N-terminal-domain-containing-protein
MPDLSAFPITQKWPAQHPDRLQLYSLPTPNGVKVSIMLEETGLPYEPHLVRFDTNDQLSPAFLSLNPNNKIPAIIDPNGPDGKPLPLFESGAILIYLADKTGQLIPKDLAGRYETIQWVMFQMGGIGPMFGQVGFFHKFAGRDYEDKRPRDRYVDESKRLLAVLDAHLANRKWVMGDTYTIADIAIFPWVRNLVGFYEAGDLVGFSEFRHVARALDAFVARPAVARGLNIPARS
>NZ_AP018111.1|WP_096470925.1|497237_498362_-|porin
MKTKLAALAALAGCSAFAHAQSSVTLYGVIDTGLLYQSTSAASFSPTAPNTGKVFRMKDGGIYSSFWGIKGSEDIGGGYKVNFKLQGSFDSGTGKLQLSDTPGAVAIFNQVASLGVSGPFGTFTAGRQIVPMIYAMADTDVRNAQFFGSVLTAWLGLNTAAGWPGTSTNGSIGALYDSNALVYQSPTFAGASIALEYAPGGVAGQFQGGTRESVVLKYSNYGLNASALYYNGHDTNPAPGVAPTGVDNNRFIYFGAKYTIRDFSVSASYGNGRNPAHADKVNLDMLSAGVGYRFTPALQVTSAAYYLKDRNRSENRSTAVVLAADYSLSKRTMVYAQVGHVNNRGTMDQMLVYGQPVAPGVGTTAAMVGLRHNF
>NZ_AP018111.1|WP_096470926.1|498715_501400_-|LuxR-family-transcriptional-regulator
MAHPPDRADAPPTELVLKTTAPRVPAQLLARARLSLAAPAFDGRPVTLVQAPAGYGKTSLLAQWRREYLALGGAVVWLSADERDDAPRLLQGLVQAVRTGCARPGFGRLIPGGASRALDGLTAWLAEVAQLSIDALLIVDDAERLPAAGLDALTYVLHNAPQNLHVVVAARRGLDHAAGDLLAGGQCTLAGPDWLRFTLDETIALVGARFAQRVDADACARLFERVDGWPLGLQLAMAAMARSADPRQAVDALAARVDGTRDRLVELLLANLSADDTAFLTRTSVADRLHPSLCAALLDDADAPDRLARDTPLFIASDDSDWCRLHPLVRDTLRDRLAAGPDAGRSVLHARAAAWLDAHGMTGEAARHAYAAGQVETAYALAQRCLEDAIKQGRINDVLDWLALLPDAELDKRPTLRVAVAWALALGERHVEAQRQIAGILADPGTPAAMRYECALILSAAAYYADEIDRFVELFEPWADFTPPATTWLAQMHANRLSARAIIVGEPARARRFQQAAPRGETAAGFGYVARWGELITGLSYLREGQIRLADDALSPALARAEADLGRRHPLTCMLAAMCAAIAYEADRVDQAAALLANRLDVLEHAGTPDTVLLGYRTAARIALLRGVEHRAIDLLEALDAMGVARRLPRLSVASLAEQVRIHAARYREATCHALVERIDAIAAAEFPSHGPLWRWPVVLLQATAHAGAALAARRWDDASAALDEAAVLAREMSMGRERIEIMALSAFALEQSGHGGLALLDEAMNLADMFGLTRTLADAHPAVADWARRVGDEAAAGDGPARHALPQPRIVPPAPRGAPSPRAVPSVVLTPKERAILELLARNLSNKEIAVALAVGEETVKWHLKNLFGKLDASSRKHAVRRALVLGLLESAP
>NZ_AP018111.1|WP_096470927.1|501642_502560_+|universal-stress-protein
MYRHLLVTVDGAPGGIDAIGHALELARAVGARVTFVLPGTEPDSRLSGARLPEHGAKVEAAARAQGLSHAIAGAGHPGAGDTSPGMLAGELGCDLIGVAALPLDADAATCAQRQYLLATSGVPVLVCPSPRSSAEARVMARCLDAHRAVGMLLQALTACGERANGPQRQTADARGALASLAALQNARFGTAAEARLFAALRARAECVTAELDELDRQRQRDAQALDVLARIAGDGLPSAAFDTALARYAHGAFEQMGRMEGAIFPAARRYLGEADWTELDEPPAGGAAATPPGANEPDDARRASD
>NZ_AP018111.1|WP_096470928.1|502578_503559_+|quinone-oxidoreductase
MAHAVRFHETGGPDVLRWEEVDVGDPGPGQVRLRHEAVGLNFADTYFRSGLYPVPLPSGIGVEAAGVVDAVGPGVTNVAAGDRVTYTGFINTLGAYGTERLIPAAPLIRLPDGIACDTAAAMTMRGLTSAYLLRRIHAFAPGDTLLLHAAAGGVGLIVSQWAKLLGLTVIGTVSSEHKADIARAHGCDHTIDYSREDVAQRVRELTDGAGVDVVFDSVGKDTFEGSLDSLKRRGLMVCVGTASGPIPPFDPQRLAMKGSLYLTRPALADYIADPAEKNDLAGELFAHVAAGRIRIEINQRYALQDAAQAHRDLESRRTTGSSVFIV
>NZ_AP018111.1|WP_096470929.1|503569_504418_+|TauD/TfdA-family-dioxygenase
MRVEPLTCAIGAELLDVSLADAVHDDGLFAEIRAQLLRHRVLFLRDQDITRAEHVAFARRFGELEDHPVAGSDPEHPGLVRIYKSPDQPNDRYENAWHSDASWRVAPPFGCVLRCVEGPPVGGDTMWANMVLAYENLPEHVKQQIDGLRARHSIEASFGAAMPIDKRLALKAQFPDAEHPVVRTHPETGEKVLYVNAFTTHFTNFHTPGRVRFGQDANPGAGQLLQYLISQAYIPEYQVRWRWKKNSVAIWDNRSTQHYAVMDYPPCVRRMERAGIVGDVPF
>NZ_AP018111.1|WP_047900685.1|504551_505607_+|3-keto-5-aminohexanoate-cleavage-protein
MQFLDDSLHPENQDKVVITVAPYGPEWMPADFPEDIPVTMDEHVQKAVDCYNAGATVLHLHVRELDGKGSKRLSKFNELLGRLRDAVPDMILQVGGSISFAPEGDGAEAKWLSDDTRHMLAELTPKPDQVTVAINTVQMNITELMNRQDIAGTSLNETAYWDAYREMTVPAGPGWVDEHLRRLQAAGIQPHFQLTGMHALETLERIIRRGVYRGPLNVTWVGIGGGFDGPNPYNFMEFVRRCPDGACITLESLMKNVLPINTVAMALGLHPRCGIEDTIIDQKGNRMTSVQQVEQCARIARELGRDIATGKEAKAIYRIGVQYDGVDETLAQLGMAPNRRPGQVSVPLRAA

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Crispr_ID: NZ_AP018111_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP018111_2

1506064-1506158

Orphan

Consensus_repeat	Method
ACCGCTTTGCATGGGACCACCCT	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NZ_AP018111_2

>merge|NZ_AP018111|2|1506064-1506158|CRISPRCasFinder
ATCGCTTCGCATCGGACAGCACAACCGCTTTGCATGGGACCACCCTGAGCACTAAAGCACCAAGGGCGGTCGACCGCTTTGCATGGGACCGCCCT

>NZ_AP018111|2|2|1506064-1506158|CRISPRCasFinder
ATCGCTTCGCATCGGACAGCACA	ACCGCTTTGCATGGGACCACCCTGAGCACTAAAGCACCAAGGGCGGTCG
ACCGCTTTGCATGGGACCGCCCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP018111.1\|WP_096471595.1\|1501084_1502464_-\|exodeoxyribonuclease-VII-large-subunit	unknown	unknown	gnl\|CDD\|234714
NZ_AP018111.1\|WP_096473065.1\|1507024_1507867_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|225464
NZ_AP018111.1\|WP_096471600.1\|1510164_1510485_-\|DUF3579-domain-containing-protein	unknown	unknown	gnl\|CDD\|371904
NZ_AP018111.1\|WP_096471592.1\|1497821_1498868_-\|2-dehydropantoate-2-reductase	unknown	unknown	gnl\|CDD\|236193
NZ_AP018111.1\|WP_011352986.1\|1500279_1500858_-\|superoxide-dismutase	unknown	unknown	gnl\|CDD\|182534
NZ_AP018111.1\|WP_065499351.1\|1505242_1505905_+\|adenylate-kinase	unknown	unknown	gnl\|CDD\|234711
NZ_AP018111.1\|WP_096471593.1\|1498860_1499385_-\|DUF962-domain-containing-protein	unknown	unknown	gnl\|CDD\|226914
NZ_AP018111.1\|WP_096471598.1\|1506199_1506958_+\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|187629
NZ_AP018111.1\|WP_096471591.1\|1497113_1497716_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_AP018111.1\|WP_096471601.1\|1511925_1513008_-\|SRPBCC-domain-containing-protein	unknown	unknown	gnl\|CDD\|223698
NZ_AP018111.1\|WP_096471594.1\|1499466_1500174_+\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
NZ_AP018111.1\|WP_096471596.1\|1502914_1503943_+\|tetraacyldisaccharide-4'-kinase	unknown	unknown	gnl\|CDD\|179349
NZ_AP018111.1\|WP_096471602.1\|1513004_1513379_-\|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|223713
NZ_AP018111.1\|WP_010090898.1\|1503923_1504118_+\|Trm112-family-protein	unknown	unknown	gnl\|CDD\|225391
NZ_AP018111.1\|WP_006482211.1\|1509730_1510003_+\|30S-ribosomal-protein-S20	unknown	unknown	gnl\|CDD\|178943
NZ_AP018111.1\|WP_096471597.1\|1504242_1505034_+\|3-deoxy-manno-octulosonate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|235473
NZ_AP018111.1\|WP_096471603.1\|1513624_1514674_-\|UDP-N-acetylmuramate-dehydrogenase	unknown	unknown	gnl\|CDD\|234593
NZ_AP018111.1\|WP_096471604.1\|1514811_1515297_+\|YajQ-family-cyclic-di-GMP-binding-protein	unknown	unknown	gnl\|CDD\|180061
NZ_AP018111.1\|WP_096471599.1\|1507875_1509426_-\|murein-biosynthesis-integral-membrane-protein-MurJ	unknown	unknown	gnl\|CDD\|223800
NZ_AP018111.1\|WP_047898860.1\|1510897_1511827_+\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|234835

Protein	Function_ID	Function_description	E-value
NZ_AP018111.1\|WP_096471595.1\|1501084_1502464_-\|exodeoxyribonuclease-VII-large-subunit	gnl\|CDD\|234714	PRK00286, xseA, exodeoxyribonuclease VII large subunit; Reviewed.	0
NZ_AP018111.1\|WP_096473065.1\|1507024_1507867_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|225464	COG2912, COG2912, Uncharacterized conserved protein [Function unknown].	9.75241e-73
NZ_AP018111.1\|WP_096471600.1\|1510164_1510485_-\|DUF3579-domain-containing-protein	gnl\|CDD\|371904	pfam12112, DUF3579, Protein of unknown function (DUF3579). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 98 to 126 amino acids in length. This protein has a conserved FRP sequence motif.	9.58904e-56
NZ_AP018111.1\|WP_096471592.1\|1497821_1498868_-\|2-dehydropantoate-2-reductase	gnl\|CDD\|236193	PRK08229, PRK08229, 2-dehydropantoate 2-reductase; Provisional.	0
NZ_AP018111.1\|WP_011352986.1\|1500279_1500858_-\|superoxide-dismutase	gnl\|CDD\|182534	PRK10543, PRK10543, superoxide dismutase [Fe].	7.07483e-106
NZ_AP018111.1\|WP_065499351.1\|1505242_1505905_+\|adenylate-kinase	gnl\|CDD\|234711	PRK00279, adk, adenylate kinase; Reviewed.	8.57966e-137
NZ_AP018111.1\|WP_096471593.1\|1498860_1499385_-\|DUF962-domain-containing-protein	gnl\|CDD\|226914	COG4539, COG4539, Predicted membrane protein [Function unknown].	4.14091e-63
NZ_AP018111.1\|WP_096471598.1\|1506199_1506958_+\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|187629	cd05371, HSD10-like_SDR_c, 17hydroxysteroid dehydrogenase type 10 (HSD10)-like, classical (c) SDRs. HSD10, also known as amyloid-peptide-binding alcohol dehydrogenase (ABAD), was previously identified as a L-3-hydroxyacyl-CoA dehydrogenase, HADH2. In fatty acid metabolism, HADH2 catalyzes the third step of beta-oxidation, the conversion of a hydroxyl to a keto group in the NAD-dependent oxidation of L-3-hydroxyacyl CoA. In addition to alcohol dehydrogenase and HADH2 activites, HSD10 has steroid dehydrogenase activity. Although the mechanism is unclear, HSD10 is implicated in the formation of amyloid beta-petide in the brain (which is linked to the development of Alzheimer's disease). Although HSD10 is normally concentrated in the mitochondria, in the presence of amyloid beta-peptide it translocates into the plasma membrane, where it's action may generate cytotoxic aldehydes and may lower estrogen levels through its use of 17-beta-estradiol as a substrate. HSD10 is a member of the SRD family, but differs from other SDRs by the presence of two insertions of unknown function. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	5.9038e-127
NZ_AP018111.1\|WP_096471591.1\|1497113_1497716_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.53875e-12
NZ_AP018111.1\|WP_096471601.1\|1511925_1513008_-\|SRPBCC-domain-containing-protein	gnl\|CDD\|223698	COG0625, Gst, Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	5.46243e-38
NZ_AP018111.1\|WP_096471594.1\|1499466_1500174_+\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	2.46509e-42
NZ_AP018111.1\|WP_096471596.1\|1502914_1503943_+\|tetraacyldisaccharide-4'-kinase	gnl\|CDD\|179349	PRK01906, PRK01906, tetraacyldisaccharide 4'-kinase; Provisional.	0
NZ_AP018111.1\|WP_096471602.1\|1513004_1513379_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|223713	COG0640, ArsR, Predicted transcriptional regulators [Transcription].	2.456e-17
NZ_AP018111.1\|WP_010090898.1\|1503923_1504118_+\|Trm112-family-protein	gnl\|CDD\|225391	COG2835, COG2835, Uncharacterized conserved protein [Function unknown].	1.8632e-25
NZ_AP018111.1\|WP_006482211.1\|1509730_1510003_+\|30S-ribosomal-protein-S20	gnl\|CDD\|178943	PRK00239, rpsT, 30S ribosomal protein S20; Reviewed.	5.46541e-19
NZ_AP018111.1\|WP_096471597.1\|1504242_1505034_+\|3-deoxy-manno-octulosonate-cytidylyltransferase	gnl\|CDD\|235473	PRK05450, PRK05450, 3-deoxy-manno-octulosonate cytidylyltransferase; Provisional.	1.81685e-141
NZ_AP018111.1\|WP_096471603.1\|1513624_1514674_-\|UDP-N-acetylmuramate-dehydrogenase	gnl\|CDD\|234593	PRK00046, murB, UDP-N-acetylmuramate dehydrogenase.	0
NZ_AP018111.1\|WP_096471604.1\|1514811_1515297_+\|YajQ-family-cyclic-di-GMP-binding-protein	gnl\|CDD\|180061	PRK05412, PRK05412, putative nucleotide-binding protein; Reviewed.	2.4e-87
NZ_AP018111.1\|WP_096471599.1\|1507875_1509426_-\|murein-biosynthesis-integral-membrane-protein-MurJ	gnl\|CDD\|223800	COG0728, MviN, Uncharacterized membrane protein, putative virulence factor [General function prediction only].	4.43553e-150
NZ_AP018111.1\|WP_047898860.1\|1510897_1511827_+\|ornithine-carbamoyltransferase	gnl\|CDD\|234835	PRK00779, PRK00779, ornithine carbamoyltransferase; Provisional.	0

>NZ_AP018111.1|WP_065499351.1|1505242_1505905_+|adenylate-kinase
MRLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGTPLGIEAKRFMDEGKLVTDDLIIGLVKERLKESDCANGYLFDGFPRTIAQADAMKDAGVAIDYVLEIDVPFSEIIERMSGRRTHPASGRTYHVKFNPPKVEGQDDVTGEPLIQRDDDKEETVKKRLEVYEAQTKPLIKYYGDWAQRGEENGLKAPQYRKISGLGSVEEIRERAFDALK
>NZ_AP018111.1|WP_096471597.1|1504242_1505034_+|3-deoxy-manno-octulosonate-cytidylyltransferase
MTHPQPFIAVIPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQSVLDAARDHGFEAVLTRADHPSGTDRLAEVAATFGWSDDTVVVNVQGDEPLIDPVLVRDVASHLAAHPACAIATAAHPIHDAADVFNPNVVKVALDARSVALYFSRAPIPWSRDAYQPHWPDVAAMPAPAFPVYRHIGLYAYRARFLRTYPSLAQAPIEQAEQLEQLRALWHGERIAVLITESAPEAGIDTPADLARVQALFQPGSK
>NZ_AP018111.1|WP_010090898.1|1503923_1504118_+|Trm112-family-protein
MDARLLEILVCPICKGPLHYDRAAQELICNADKLAYPIRDGIPVMLVDEARQTVEGTPVDPAGR
>NZ_AP018111.1|WP_096471596.1|1502914_1503943_+|tetraacyldisaccharide-4'-kinase
MSAPGGPLGRLEARLTREWQRRGALAWALTPFACVFGLCAALRRTAYAQGWKKPVDVGVPVVVVGNVTVGGTGKTPTVIALVDALRAAGFTPGIVSRGYGANVKAPTAVTPASRASVGGDEPLLIARRTGAPVWVCPDRVAAAQAMRAAHPDVDVIVSDDGLQHYRLARTVELVVFDHRLGGNGFLLPAGPLREPLSRHRDATLVNDPYSGALPPWPDTYSLSLTPGAAWHLDQPALRRPLSQFAHERVLAAAGIGAPERFFATLRAAGLAPATRALPDHYAFADNPFVDDAVDAILITEKDAVKLGASWRDARLWVVPVEAALDPRLIALVVEKLRGRSPA
>NZ_AP018111.1|WP_096471595.1|1501084_1502464_-|exodeoxyribonuclease-VII-large-subunit
MPSDSPFAAPGATRGDEVIPVSALNRAISTMLERSFPLLWISGEVSNFTRAASGHWYFSIKDQQAQMRCVMFRGRAQYAEFTPREGDRIEVRAVVTMYEPRGEVQLNVEAVRRTGQGRLYEAFLRLKAQLESEGLFAPERKRPLPAHPRAIGIVTSLQAAALRDVLTTLARRAPHIPVIVYPAPVQGAGSAEKLVAAVEAANARREVDVLLVCRGGGSIEDLWSFNDEALARAIAASELPVVSGVGHETDFTIADFAADVRAPTPTGAAELASPQRALLLREVGDRQRALARGMERRLEQRAQQLDWLARRLVSPAERLQRQRTHVEQLAVRLASAASRPVRDARARFALAQLRWQRARPDPSQARQALAGLSQRLALALQRRHERDTARVSACAARLEVLSPKRTLERGYAALIDAQTGRAVRAPSALKPQRRLTVHLAEGSADVSLADVQPRLTDTI
>NZ_AP018111.1|WP_011352986.1|1500279_1500858_-|superoxide-dismutase
MAHTLPPLPYAEDALAPTISLETIQYHYGKHHQAYVTNLNNLIPGTEFENLSLEEIVKKSSGGIFNNAAQIWNHTFFWNSLSPNGGGAPTGALGDAINAKWGSYDAFKEAFTKAAVGTFGSGWAWLVKKADGSLDIVSTSNAATPLTTADKALLTIDVWEHAYYIDYRNARPKFVEAFWNIVNWDFAAKNFA
>NZ_AP018111.1|WP_096471594.1|1499466_1500174_+|Crp/Fnr-family-transcriptional-regulator
MPSPLAPYLPQIEANPWFAALPRTLRADLLDRAALRRLPAGHALFRRGDPPCGLYAVLAGSLTIGAVDPQGKEALLTVAEPVTWFGEIALFDGQPRTHDAIALDDALLLHVPQAALLAILDATPQYWRQFALLMAQKLRLSFLTVESMSVMPAAQRLAARLLMIAEGYGGISAGRTRVRLSQETLASMLSLTRQTTNQLLKALQADGVVRLHVGEIELVDIDALRRASGLGGGTH
>NZ_AP018111.1|WP_096471593.1|1498860_1499385_-|DUF962-domain-containing-protein
MKTLEDHLSQYAAYHRDARNIATHLVGIPMIVFAVEVLLSRPAIGMPAGIALSPALLLAIAFAVFYLRLDLRFGIVMTALFALGLWAAQALALLPTAQWLAIGIGAFVVGWIVQFVGHWFEGRKPAFVDDLVGLMVGPLFVVAEVAFFAGLRGDVRREVERRAGPVHGGAHSHV
>NZ_AP018111.1|WP_096471592.1|1497821_1498868_-|2-dehydropantoate-2-reductase
MSDAPVCVVGAGAVGCYLGGRLAAAGAPVTLVGRARIGDAIHLHGLTLTDQHGYRATLAPADVAFATDPAAAATARLVLVAVKSAATRDAAAQLAGVLRPGTVVISFQNGLHNADVLRDALPQATVLAGMVPFNVIERGPGAFHQGSAGALAADASPALQPFAGAFARAGLPLALHRDMPAVQWAKLLLNLNNAVNALANLPLRDELAQRAYRRCVALAQREALHWLARAAIRPARLTPLPAAWIPAVLDLPDAAFRVVGGRMLAIDPLARSSMSDDLAARRATEVEWINGEIVRLAARFGAQAPVNARLCALVHDAENAAARPAWRGDALWAELAAQVPRTGAVRAA
>NZ_AP018111.1|WP_096471591.1|1497113_1497716_-|class-I-SAM-dependent-methyltransferase
MVDRPTLDAYDAHAAQYAQDWLDQAAPDDMYALLEQHFSPGPTADVGCGAGRDTAWLASRGYDVRGYDASAALLDEARRRHPDLTFELAALPALAGVPSGAFRNVLCETVVMHLEQADAAAAAARLADLLMPGGTLYLSWRVAGNGALRDERGRLYTPLDSARMHAALGAGMHVIDEHEVVSASSGKRVHRLIVRKAAAA
>NZ_AP018111.1|WP_096471598.1|1506199_1506958_+|SDR-family-NAD(P)-dependent-oxidoreductase
MEIRGNVFLITGGASGLGAGTARMLAQAGAKVVLADLNEAAGGALATELGGIFVRCDVSSEADAQAAVDAATRAGTLRGLVNCAGIAPAAKTVGKDGAHPLDVFAKTINVNLVGTFNMIRLAAAAMAATAPTADGERGVIVSTASVAAFDGQIGQAAYAASKAGVAGMTLPIARDLSRSGIRVMTIAPGLFETPMLLGMPKDVQDALGAMVPFPPRLGKPAEYAMLVRQIVENPMLNGEVIRLDGAIRMQPK
>NZ_AP018111.1|WP_096473065.1|1507024_1507867_-|tetratricopeptide-repeat-protein
MTRVLDYFSTLVADDDSLPVTETALSLAQDAYPDLDLQGTLAELDMLAARLRRRLADDADLKGRVAALNDFFFRELGFACNHNDYYDPDNSHLNAVLKRRRGIPISLSVLYLELAEQVGVPARGVSFPGHFLLRVTLPDGDLIIDPTNGHSLSEAEMVEMLEPYVARAAGAVDSALRALLQPATSREIIARMLRNLKTIYLQTERWQRLLAVQQRLVILLPEQLDEVRDRGFAYARLDYLRPALEDLEQYLGERPEADDATVVESQVTELRQRMQRDGED
>NZ_AP018111.1|WP_096471599.1|1507875_1509426_-|murein-biosynthesis-integral-membrane-protein-MurJ
MNLFRALLTVSGFTLLSRVTGLARETLIARAFGASQYTDAFYVAFRIPNLLRRLSAEGAFSQAFVPILAEFKNQQGHDATKALVDAMSTVLAWALAVLSVAGIAGASWVVFAVASGLHTDGQAFPLAVTMTQIMFPYIVFISLTTLASGVLNTYKSFSLPAFAPVLLNVAFIAAAVFVAPHLKVPVFALAWAVIVGGVLQFLVQLPGLRKIDMVPLIGLNPLRALRHPGVKRVLAKMVPATFAVSVAQLSLIINTNIASRLGQGAVSWINYADRLMEFPTALLGVALGTILLPSLSKAHVDADSTEYSALLDWGLRVTFLLAAPSALALFFFATPLTATLFNYGKFDAHTVTMVARALATYGIGLVGIILIKILAPGFYAKQDIKTPVKIAIGVLIVTQISNYVFVPLIGHAGLTLSIGVGACLNSLLLFLGLRKRGIYQPSPGWPRFFMQLVGATLVLAGVMHWFSISFDWTGMRTQPLDRIVLMAACLVLFAALYFGMLWVMGFKYAYFRRRAK
>NZ_AP018111.1|WP_006482211.1|1509730_1510003_+|30S-ribosomal-protein-S20
MANSAQARKRARQAAKANSHNSALRSKFRTAIKSVRKAVEAGDQAKAAELFKAAVKTIDTIADKKIVHKNKAARSKSRLAAAVKGLQAAA
>NZ_AP018111.1|WP_096471600.1|1510164_1510485_-|DUF3579-domain-containing-protein
MAETPPTEFFIQGITKDGKKFRPSDWSERLAGVMACFGPGASGPNARLKYSLYVRPTMLGDLKCVILDSRLRDIEPMAFDFVLNFAKDNHLVVTEACELPEYGAKK
>NZ_AP018111.1|WP_047898860.1|1510897_1511827_+|ornithine-carbamoyltransferase
MTAKTIRHYLQFKDFSLEDYEYVLERTGILKRKFKNYETYHPLHDRTLAMIFEKSSTRTRLSFEAGIFQLGGHAVFMSTRDTQLGRGEPVEDSAQVISRMVDIIMIRTFEQEVIKRFAENSRVPVINGLTNEYHPCQVLADIFTYYEHRGPIAGKTVAWVGDANNMLYTWIEAAQILGFKLRLSTPPGYALDMKLVSPDSAPFYEVFDDPNEACKGADLVTTDVWTSMGFEAENEARMKAFADWCVDEEMMGHANPDALFMHCLPAHRGEEVTAGVIDGPQSVVWDEAENRLHVQKALMEFLLLGRLKH
>NZ_AP018111.1|WP_096471601.1|1511925_1513008_-|SRPBCC-domain-containing-protein
MSQAATFHLELNRFIRAPRERVFDAFTNETALATWHCPRGMGVIEASADARVGGKYRIVMGGRDGSRHIAGGEYQKVDRVDFLAYTWAWEAGSMPADLKTLIEVTFTDKDGGTHLHMRHSGFPSEQERDSHMGGWQSVFNRLNDLLDPDGSAGTVVVIGDPRSSYCRTVRMALVEKGVAYTLQPLPPHSPEVLAHNPFGRVPAFCDGPIEFYETRAILGYIDEAFDGPSLLAQWGVTAHARGEQWISLINCHAYDAMVRRYVLQYVFLKGENGQPDRAVIDAALPEIDKHLQVFDAAYGGRDYLVGSGLSMADLFLTPILAYVGMFPEGAELLRKYPNVTRAQAVMRERPSFAATQPAPG
>NZ_AP018111.1|WP_096471602.1|1513004_1513379_-|helix-turn-helix-transcriptional-regulator
MHSTSDTLSAVFAALADPTRRAILVRLAEGAAPVSELARPFDMSAPAISKHLRVLSEAGLIEREVNARWRICRLRADGMRDAHGWLEAYRQYWEESLDRLTAFVEQTCAGGTAGDDALPRREKS
>NZ_AP018111.1|WP_096471603.1|1513624_1514674_-|UDP-N-acetylmuramate-dehydrogenase
MPMPPDDSALSLLPDHPLAAHNTFGIDANARFAARITHASQFEALHRDPRVANLPQLVLGGGSNVVFTRDFDGVVLLDEIAGRRVVREDDDAWYVEAGGGENWHAFVAWTLEHGMPGLENLALIPGTVGAAPIQNIGAYGLEMKVYFDSLVAVELATGRSERFDAARCAFGYRDSFFKREGRGRFAIVSVTFRLPRQWTPRLGYADVTRELDARGIAPDAATPRDVFDAVVAIRRAKLPDPLVLGNAGSFFKNPVIDAAQFDALRTRAPDVVSYPQPDGQVKLAAGWLIDRCGWKGRVLGAAAVHDRQALVLVNRGGATGADVLALARAIQHDVFAKFGVELEPEPVCL
>NZ_AP018111.1|WP_096471604.1|1514811_1515297_+|YajQ-family-cyclic-di-GMP-binding-protein
MPSFDVVSEANMIEVKNAIEQSNKEISTRFDFKGSDARVEQKERELTLFADDDFKLGQVKDVLISKLAKRNVDVRFLDYGKVEKIGGDKVKQIVTVKKGVTGDLAKKIVRLVKDSKIKVQASIQGDAVRVAGTKRDDLQSVIAMLRKDVTDTPLDFNNFRD

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Crispr_ID: NZ_AP018111_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP018111_3

2103263-2103339

Orphan

Consensus_repeat	Method
CTGATGCGCCAACTCCGGCCGAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP018111_3

>merge|NZ_AP018111|3|2103263-2103339|CRISPRCasFinder
CTGATGCGCCAACTCCGGCCGACGTCCCACAAGGGGATGGGGCCGAAGTAAGCGCTGAAGCGCCAACTCCGGCCGAC

>NZ_AP018111|3|3|2103263-2103339|CRISPRCasFinder
CTGATGCGCCAACTCCGGCCGAC	GTCCCACAAGGGGATGGGGCCGAAGTAAGCG
CTGAAGCGCCAACTCCGGCCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP018111.1\|WP_096472005.1\|2096122_2097763_-\|GMC-family-oxidoreductase-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|235000
NZ_AP018111.1\|WP_096472007.1\|2098488_2099931_+\|coniferyl-aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143451
NZ_AP018111.1\|WP_011353523.1\|2101087_2101300_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP018111.1\|WP_096472009.1\|2102114_2102996_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769
NZ_AP018111.1\|WP_096472010.1\|2103647_2104691_-\|L-glyceraldehyde-3-phosphate-reductase	unknown	unknown	gnl\|CDD\|381376
NZ_AP018111.1\|WP_157776348.1\|2097984_2098449_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP018111.1\|WP_096472015.1\|2109184_2109487_-\|HigA-family-addiction-module-antidote-protein	unknown	unknown	gnl\|CDD\|274228
NZ_AP018111.1\|WP_096472002.1\|2092652_2094206_+\|flagellar-protein-export-ATPase-FliI	unknown	unknown	gnl\|CDD\|274607
NZ_AP018111.1\|WP_006482984.1\|2106816_2108004_-\|methionine-adenosyltransferase	unknown	unknown	gnl\|CDD\|235374
NZ_AP018111.1\|WP_096472013.1\|2106364_2106706_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP018111.1\|WP_096472008.1\|2100003_2101029_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|236974
NZ_AP018111.1\|WP_014895742.1\|2103352_2103538_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP018111.1\|WP_096472017.1\|2110782_2111508_+\|DUF484-family-protein	unknown	unknown	gnl\|CDD\|225701
NZ_AP018111.1\|WP_096472001.1\|2091975_2092659_+\|flagellar-assembly-protein-FliH	unknown	unknown	gnl\|CDD\|235562
NZ_AP018111.1\|WP_096472011.1\|2104876_2105083_+\|DUF3185-family-protein	unknown	unknown	gnl\|CDD\|378652
NZ_AP018111.1\|WP_096472004.1\|2094701_2096066_+\|flagellar-hook-length-control-protein-FliK	unknown	unknown	gnl\|CDD\|350657
NZ_AP018111.1\|WP_096472012.1\|2105237_2106011_-\|phytanoyl-CoA-dioxygenase-family-protein	unknown	unknown	gnl\|CDD\|227609
NZ_AP018111.1\|WP_096472014.1\|2108269_2109154_+\|lipid-A-biosynthesis-lauroyl-acyltransferase	unknown	unknown	gnl\|CDD\|180770
NZ_AP018111.1\|WP_096472003.1\|2094211_2094670_+\|flagellar-export-protein-FliJ	unknown	unknown	gnl\|CDD\|235563
NZ_AP018111.1\|WP_096472016.1\|2109875_2110745_+\|diaminopimelate-epimerase	unknown	unknown	gnl\|CDD\|234768

Protein	Function_ID	Function_description	E-value
NZ_AP018111.1\|WP_096472005.1\|2096122_2097763_-\|GMC-family-oxidoreductase-N-terminal-domain-containing-protein	gnl\|CDD\|235000	PRK02106, PRK02106, choline dehydrogenase; Validated.	0
NZ_AP018111.1\|WP_096472007.1\|2098488_2099931_+\|coniferyl-aldehyde-dehydrogenase	gnl\|CDD\|143451	cd07133, ALDH_CALDH_CalB, Coniferyl aldehyde dehydrogenase-like. Coniferyl aldehyde dehydrogenase (CALDH, EC=1.2.1.68) of Pseudomonas sp. strain HR199 (CalB) which catalyzes the NAD+-dependent oxidation of coniferyl aldehyde to ferulic acid, and similar sequences, are present in this CD.	0
NZ_AP018111.1\|WP_096472009.1\|2102114_2102996_+\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	1.92478e-11
NZ_AP018111.1\|WP_096472010.1\|2103647_2104691_-\|L-glyceraldehyde-3-phosphate-reductase	gnl\|CDD\|381376	cd19150, AKR_AKR14A1, Escherichia coli L-glyceraldehyde 3-phosphate reductase (GPR/YghZ/AKR14A1) and similar proteins. Escherichia coli L-glyceraldehyde 3-phosphate reductase (GPR/YghZ), also called GAP reductase, is a founding member of aldo-keto reductase family 14 member A1 (AKR14A1). It catalyzes the stereospecific, NADPH-dependent reduction of L-glyceraldehyde 3-phosphate (L-GAP). It is also involved in the stress response as a methylglyoxal reductase which converts the toxic metabolite methylglyoxal to acetol in vitro and in vivo.	0
NZ_AP018111.1\|WP_096472003.1\|2094211_2094670_+\|flagellar-export-protein-FliJ	gnl\|CDD\|235563	PRK05689, fliJ, flagella biosynthesis chaperone FliJ.	2.74631e-23
NZ_AP018111.1\|WP_096472015.1\|2109184_2109487_-\|HigA-family-addiction-module-antidote-protein	gnl\|CDD\|274228	TIGR02607, Virulence-associated_protein_I, addiction module antidote protein, HigA family. Members of this family form a distinct clade within the larger family HTH_3 of helix-turn-helix proteins, described by pfam01381. Members of this clade are strictly bacterial and nearly always shorter than 110 amino acids. This family includes the characterized member HigA, without which the killer protein HigB cannot be cloned. The hig (host inhibition of growth) system is noted to be unusual in that killer protein is uncoded by the upstream member of the gene pair. [Regulatory functions, DNA interactions, Regulatory functions, Protein interactions, Mobile and extrachromosomal element functions, Other].	2.63085e-28
NZ_AP018111.1\|WP_096472002.1\|2092652_2094206_+\|flagellar-protein-export-ATPase-FliI	gnl\|CDD\|274607	TIGR03496, FliI_clade1, flagellar protein export ATPase FliI. Members of this protein family are the FliI protein of bacterial flagellum systems. This protein acts to drive protein export for flagellar biosynthesis. The most closely related family is the YscN family of bacterial type III secretion systems. This model represents one (of three) segment of the FliI family tree. These have been modeled separately in order to exclude the type III secretion ATPases more effectively. [Cellular processes, Chemotaxis and motility].	0
NZ_AP018111.1\|WP_096472016.1\|2109875_2110745_+\|diaminopimelate-epimerase	gnl\|CDD\|234768	PRK00450, dapF, diaminopimelate epimerase; Provisional.	2.20507e-146
NZ_AP018111.1\|WP_096472008.1\|2100003_2101029_-\|serine/threonine-protein-kinase	gnl\|CDD\|236974	PRK11768, PRK11768, serine/threonine protein kinase.	0
NZ_AP018111.1\|WP_096472017.1\|2110782_2111508_+\|DUF484-family-protein	gnl\|CDD\|225701	COG3159, COG3159, Uncharacterized protein conserved in bacteria [Function unknown].	7.4705e-48
NZ_AP018111.1\|WP_096472001.1\|2091975_2092659_+\|flagellar-assembly-protein-FliH	gnl\|CDD\|235562	PRK05687, fliH, flagellar assembly protein FliH.	5.55571e-82
NZ_AP018111.1\|WP_096472011.1\|2104876_2105083_+\|DUF3185-family-protein	gnl\|CDD\|378652	pfam11381, DUF3185, Protein of unknown function (DUF3185). Some members in this bacterial family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	7.75869e-14
NZ_AP018111.1\|WP_096472004.1\|2094701_2096066_+\|flagellar-hook-length-control-protein-FliK	gnl\|CDD\|350657	cd17470, T3SS_Flik_C, C-terminal domain of flagellar hook-length control protein FliK and similar domains. The flagellar hook-length control protein FliK is a soluble cytoplasmic protein that is secreted during flagellar formation. It controls hook elongation by two successive events: by determining hook length and by stopping the supply of hook protein. It contains an N-terminal domain that determines hook length and a C-terminal domain that is responsible for switching secretion from the hook protein to that of the filament protein, by interacting with FlhB, the switchable secretion gate.	1.67419e-21
NZ_AP018111.1\|WP_096472012.1\|2105237_2106011_-\|phytanoyl-CoA-dioxygenase-family-protein	gnl\|CDD\|227609	COG5285, COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin [Secondary metabolites biosynthesis, transport, and catabolism].	4.8126e-31
NZ_AP018111.1\|WP_096472014.1\|2108269_2109154_+\|lipid-A-biosynthesis-lauroyl-acyltransferase	gnl\|CDD\|180770	PRK06946, PRK06946, lipid A biosynthesis lauroyl acyltransferase; Provisional.	0
NZ_AP018111.1\|WP_006482984.1\|2106816_2108004_-\|methionine-adenosyltransferase	gnl\|CDD\|235374	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated.	0

>NZ_AP018111.1|WP_096472009.1|2102114_2102996_+|DMT-family-transporter
MVSFKRALAAHGATSLFVLLWSSGAIFAELGLRHASAFVFLTARFALASLVLLALAFVRKRWLPPRGERRMAALTGLLMMGGYSIFYLLALERGIAPGVLATILGVQPILTLAIVERRWQPMRVAGLALSLAGLALVVCRGVGDAGLPVAGVACALTALVALTVGSLLQKRVRAAPADVLPLQNAIGLALCVAIAPFRPVSLDMSWAFVVPLLWLGIVISVIAQLLFYRLMQRGDLVNVTSLFYLVPVVTTLMDAVWLGNRPEPLALAGMGAIIAGLALVFRAPAARMQPDRV
>NZ_AP018111.1|WP_011353523.1|2101087_2101300_-|hypothetical-protein
MHVGSIVCTTHIAVPKGARGIVQRVLGDMAMVTWYAGVPGESKELNTEPFFLEDLIDTGESVLPAGAALH
>NZ_AP018111.1|WP_096472008.1|2100003_2101029_-|serine/threonine-protein-kinase
MNEVTSAPASPAGPPPFAGLTPECVLDALDSVLMPAGLRTDGRLLALNSYENRVYQVGIEDGPPVVAKFYRPARWSDDAILEEHAFVADLAAREIPAVPARTFDGRTLHAFDGFRFSVFERRGGRAPDLDRSDTLEWLGRFIGRIHAVGATQPYVARPVLDIKTFGYEPRDYLLAHDFIPDDVRPAYETAVTLALEGVEAAFERAGELRMLRTHGDCHPSNVLWTDAGPHFVDFDDSRMAPAIQDLWLLLPGDREGASRALADLLAGYEDFCEFEPRELHLVEALRTLRLIHYAAWLARRWDDPAFPAAFPWFNTHRYWEARVLELREQIGAMQEGPLWPV
>NZ_AP018111.1|WP_096472007.1|2098488_2099931_+|coniferyl-aldehyde-dehydrogenase
MKNDLPELAPQALPSADALTSLLRDQRAAYLRAPYPAWETRVQHLRALRAMLLDHADALAEAISADFGHRSKQEVLLSEIWMAKEEIDDALKHGKRWMKPIRKPMNKWLRPARAKVIPQPLGVVGIVVPWNYPVLLAAGPLICALAAGNRAIIKMSELTPRTSALFEQLIAKTFTRDHVAVVNGDAEVGAAFSGLPFDHLLFTGSTQVGRHVMRAAADNLTPVTLELGGKSPAIVGPNARFDAAVDAIVAGKTLNAGQTCIAPDYVLLPRGMEAAFIERARARFAKMYPDLSTNGDYTTIVSPRHYARLQQLASDAQAAGAQLHPLSDAQSDPASRRFVPCAVTQVPAASQLMQEEIFGPLLPLVPYERLDEAIAYVNARPRPLALYLFDEDGGTIDRVMRETISGGVTVNEALMHIACGSLPFGGVGASGMGAYHGYDGFVTFSKMKPVLTQARLNTRGLIAPPYGKRFAAVIKLMLKL
>NZ_AP018111.1|WP_157776348.1|2097984_2098449_+|hypothetical-protein
MQRQVLQAVCRPGCPDAPHAARISFQTAARARTVGVMRAADRNRTARVAADRLDGCPPQRHDVLRPVSACASRCPASVRRQALAPQRRVPGSSRIARHAHAPQRGFRMQIPSRGCDARRTLQPVFEHPSHPAPRRATHTTPIRVAALAERSRAA
>NZ_AP018111.1|WP_096472005.1|2096122_2097763_-|GMC-family-oxidoreductase-N-terminal-domain-containing-protein
MQYDYIIVGGGSGGSSLAGRLADACPDATIALIEAGSHTERNLLVNMPVGIAALVPFKLGTNYGYETVPQPGLGGRRGYQPRGRGMGGSSAINAMIYTRGHPGDYDEWAQLGATGWGWQDVLPYFRRAEGNERGADAWHGADGPLSVSDLRFRNPFSERFIQAAHAAGYPLNDDFNGATQEGVGFYQVTHRDGSRCSVARAYIYGRNRPNLHVITDATVLRVGFDGKRAVGVVVSRNGRVETLVARAEVILSAGAFNSPQLLMCSGIGPAEQLRRHGIAVVQDAPDVGTNLIDHIDFIINTRVNSSELVGVCLRGIAKMTPALARYFSSRTGMMTSNVAEAGGFIKSDPSLERPDLQLHFCTALVDDHNRKMHWGFGYSLHVCALRPFSRGTVALASGDARDAPLIDPRFFSDTRDLDLLVRGTQAMRRILSQAPLASQGGRELYTRADQSEAELRATIVEHADTIYHPVGTCRMGSDARAVVDPQLRVRGVEGLRVVDASVMPTLVGGNTNAPSVMIGERAADFIAAARKGGVPSGEAAAAVHGR
>NZ_AP018111.1|WP_096472004.1|2094701_2096066_+|flagellar-hook-length-control-protein-FliK
MPPLPLLAALIDTAGAALKAARGSGSSGAAAGNDAATATTAVPFAQTLKQSVVTRRDAANSATPDASTTQVASKLAAGTKPSGTDDDQSTDDTNAAATPNPDAGALAAAAAVQAQLQARTDNATPADAATAAAAASAQKTAVSGQPDATATLADHAAKDAAALPATPASSRDALQAALAKLTGGSGAISMPSTGTAASTSAQAPTSSASTAAAPLTPKVPTFDRTLADAKGALATQQTPTQATAQALQADTNAQSGAQHALAVASEATDPAASATLAAGATAAAAAQANLQLSPAASAIAAANTHVLAPHVGTADWTDALSQKVVFLSNAHQQSAELTLNPPDLGPLQVVLRVADNHAHALFVSQHAQVRDAVEAALPKLREAMEAGGLGLGSASVSDGGFASQQQNPQQTFAGGQSSRRGNGGSSAVDAPADAAQSAPAAASVSRAGLVDTFA
>NZ_AP018111.1|WP_096472003.1|2094211_2094670_+|flagellar-export-protein-FliJ
MAHGFPLQLLLDRAQEDLDSAAKQLGTAQRDRTSAAEQLDALLRYRDEYHARFSQSAQHGMPAGNWRNFQAFIDTLESAIAQQRNVLAAAEVRIDEARPNWQQKKRTVGSYEILQARGVAQEAQRDARREQRDSDEHAAKILRMRADAARSS
>NZ_AP018111.1|WP_096472002.1|2092652_2094206_+|flagellar-protein-export-ATPase-FliI
MVTRSPESLAHDGMTPLERELALASFGPAAPHDTAHDAKPHATAAAGAAPGTEPRAPHNPHLAHWRTHLNGLAARSHRALPLRPCGRLTRAAGLVLEAIGLRLSVGAECQIELPPGSTLPHAEAEVVGFAGDRLFLMPTTDVAGVLPGARVWPLESAPVADPLAGAKRLPVGWEMLGRVVDASGRPLDGLGPLASKVDAPLSAPSINPLDREPIHHVLDVGVRAINALLTVGRGQRMGLFAGSGVGKSVLLGTMARYTSAEVIVIGLIGERGREVKEFIEQILGEDGLARSVVVAAPADVSPLLRMQGAAYATSLAEYFRDQGKHVLLLMDSLTRYAMAQREIALAIGEPPATKGYPPSVFAKLPALVERTGNGPEGGGSITAFYTVLTEGDDQQDPIADSARAILDGHIVLSRTLAEAGHYPAIDIEASISRAMTALIDETHLDHVRQFKQMLSRYQRNRDLIAVGAYAPGRDAQLDRAIALYPRIEAFLQQGFRECAPFASSLAGLDALFDAYGG
>NZ_AP018111.1|WP_096472001.1|2091975_2092659_+|flagellar-assembly-protein-FliH
MSDSASDRAGTLTAYQRWEMASFDPPPPPPPPDDAAAAAAALAEELQRVRDAAHAEGHAAGHVEGQALGYQAGFEQGREQGFEAGLTDAREQAAQLAALAASFREAVSTAEHDLASDIAQLALDIAQQVVRQHVKHDPAALVAAVRDVLAAEPALSGAPHLAVNPADLPVVEAYLQDDLDTLGWNVRTDASIERGGCRAHAATGEVDATLPTRWQRVAAAIGKVSTW
>NZ_AP018111.1|WP_014895742.1|2103352_2103538_+|hypothetical-protein
MTTYFTIGDFILLIPMALAGALFLGAVPCATEFRHNLLRVLGVILGVGVAVLLVEGLPALL
>NZ_AP018111.1|WP_096472010.1|2103647_2104691_-|L-glyceraldehyde-3-phosphate-reductase
MAYEAASERYADMQYRTCGKSGLKLPALSLGLWHNFGDSTPISTQREILRTAFDLGINHFDLANNYGPPYGSAETNFGRLLKEDFRPYRDELLISTKAGWDMWPGPYGSGGGSRKYVLASLDQSLQRMGLDYVDIFYSHRFDAHTPLEETAGALASAVQQGKALYIGISSYSAAKTREMAGLLAQYKVPLLIHQPSYNMLNRWIESDLLGTLDDVGAGSIAFTPLAQGLLTSKYLNGVPADARVNKPGGGSLKQDHLSADNLEHVRKLNAIAERRGQSLAQMALAWVLRDGRVTSALIGASRAEQVRENVGALKNLEFSAEELAEIDRYATEGGINLWEKPSTDQAI
>NZ_AP018111.1|WP_096472011.1|2104876_2105083_+|DUF3185-family-protein
MSRVISVALLVGGVLLLYFGGQSFHSLNDNMSRFFTGSPATKTILLIVGGAVASFIGLIGLAMPGGKR
>NZ_AP018111.1|WP_096472012.1|2105237_2106011_-|phytanoyl-CoA-dioxygenase-family-protein
MSSPLQSESIRAQVAELRERGFVVARGLVSEQQCAALKQIAERQLQEAAEPIEFEADLRYPGAPESKHAPGGHTVRRLLDAYSRDPAFAERAIAPEIGAWMREYFGEEPVLSRAHHNCMMTKHPAYGSLTGWHRDFRYWAFERSDMVSVWLALGPETNENGALWLVPGSHTAEFGPEAFDDAKFFRGDLPENRKMIDAATCPSLQAGDVVFFHSNTLHSAGQNRSDQVKFSLVYTYHGASNRPVPGTRSAAKAEVQF
>NZ_AP018111.1|WP_096472013.1|2106364_2106706_+|hypothetical-protein
MPFRLTSRLSRTAKRIVPPAPARPLRHHRARTQALAERTHAHSRLDGIRAWFHAFFSMVSTQAFARRAGLRSLLQKPSSLRALALRRALGPQRRVNRPRRLAASDGWFGFGAR
>NZ_AP018111.1|WP_006482984.1|2106816_2108004_-|methionine-adenosyltransferase
MANDYLFTSESVSEGHPDKVADQISDAILDAILEQDKYSRVAAETLCNTGLVVLAGEITTTANIDYIQIARDTIKRIGYDNTDYGIDYKGCAVLVAYDKQSPDIAQGVDRAHDDNLDQGAGDQGLMFGYACDETPELMPLPIYLSHRLVERQASLRRDGRLQWLRPDAKSQVTVRYVDGKPDSIDTVVLSTQHAPDIELPALREAVIEEIIKPTLPADLIKGDIKFLVNPTGRFVIGGPQGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLASRALIQVSYAIGVAEPTSVMVNTFGTGRVSDAVITKLVREHFDLRPKGIIKMLDLLRPIYEKTAAYGHFGREEPEFSWEATDKALALAEAAGVEPTARVA
>NZ_AP018111.1|WP_096472014.1|2108269_2109154_+|lipid-A-biosynthesis-lauroyl-acyltransferase
MLGRLGTHLAIGFLKLLALLPYGLTARLGDGLGWLLYQIPSRRKRIVHTNLKLCFPDWSDERREEVAGQHFRHAIRSYVERSVQWFGSAKKLDKLIQVDSAIDLTDPDLPPTLFLGLHFVGIEAGSIWLNRSLQRRCGSLYQPFSNAVLEEEAKKARGRFDAEMVGRADSARVVLRWLRDRKPVMLGADMDYGLRNSTFVPFFGVPACTLTAVGRLAKTGRAQLVPFIGEVLPNYKGYRLRVFKPWDHYPTGDDDLDARRMNEFLEEQIPLMPEQYYWVHKRFKTRPPGEPSLY
>NZ_AP018111.1|WP_096472015.1|2109184_2109487_-|HigA-family-addiction-module-antidote-protein
MTRIFNPPHPGEALRDDVLPALGLAVTEAAAQLGVTRAALSRILHGHAGISPETALRLEAWLGEDNGGRADLWLAQQVAFDLWQARAKGAPKVARAQARA
>NZ_AP018111.1|WP_096472016.1|2109875_2110745_+|diaminopimelate-epimerase
MKLSFTKMHGAGNDFVVLDGYSRALPPLTEAQVRALANRHFGIGADQLLLVEKPTVDGADFKYRIFNCDGGEVEHCGNGARCFVKFVSDRGLTDKRSVRVQVMKGLITLTLQDNGEVVVDMGAPVFAPAQVPFDASGLDGRTEGRDTLWPLDVGGATRWISTVSMGNPHAVQVVDDAEAYPVLEEGPLIELHARFPQRVNAGFMQIVSRHEVKLRVYERGAGETLACGTGACAAVAAGIRRGLLDSPVTVHTHGGTLTIGWDGARDESAALMMAGPAATVFEGEIDLNA
>NZ_AP018111.1|WP_096472017.1|2110782_2111508_+|DUF484-family-protein
MNDREVADYLLANPEFFAQHAELLATIRLANPHGKAAISLQERQMEMLRDKNKHLERRLAELVRYGHENDSLSAKFSRWTARVIAERDPYALPRTIADGIADVFDVPQTALRVWDVADTYAQADFARQVGEEVRLFTNGLSTPYCGANTGFEAAQWLAPAVAASAANAAEGAEAVPAGDGSATSVALLALRAPLAGADAPAFGLLVLGSPDPRRFHDGMATDFLAQIATLASAALTRLLPH

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Crispr_ID: NZ_AP018111_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP018111_4

2313650-2313857

Orphan

Consensus_repeat	Method
GAGTAAGCGCTGAAGCGCTAACTC	CRT

4 spacers

The CRISPR arrays of NZ_AP018111_4

>merge|NZ_AP018111|4|2313650-2313857|CRT
GAGTAAGCGCTGAAGCGCTAACTCCCGTCGACTGCCGCAGGGCAAGAGTAAGCGCTGAAGCGCTGACTCTTGCCAACCGCGGCATGGGGCGGGAGTAAGTGCTGAAGCACTAACTCCGGTCGACCGCCGTGGGGCAAGAGTAAGCGCTGAAGCGCCAACTCTTGCCAACCGCGGCATGGGACGGGAGTAAGCGCTAAAGCGCTAACTC

>NZ_AP018111|4|1|2313650-2313857|CRT
GAGTAAGCGCTGAAGCGCTAACTC	CCGTCGACTGCCGCAGGGCAA
GAGTAAGCGCTGAAGCGCTGACTC	TTGCCAACCGCGGCATGGGGCGG
GAGTAAGTGCTGAAGCACTAACTC	CGGTCGACCGCCGTGGGGCAA
GAGTAAGCGCTGAAGCGCCAACTC	TTGCCAACCGCGGCATGGGACGG
GAGTAAGCGCTAAAGCGCTAACTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP018111.1\|WP_096472141.1\|2314542_2316270_+\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|236236
NZ_AP018111.1\|WP_006477288.1\|2313875_2314301_+\|F0F1-ATP-synthase-subunit-epsilon	unknown	unknown	gnl\|CDD\|234796
NZ_AP018111.1\|WP_034183834.1\|2307305_2308157_+\|F0F1-ATP-synthase-subunit-A	unknown	unknown	gnl\|CDD\|235617
NZ_AP018111.1\|WP_096472138.1\|2306671_2307196_+\|ATP-synthase-subunit-I	unknown	unknown	gnl\|CDD\|377159
NZ_AP018111.1\|WP_096472137.1\|2304974_2306105_+\|anion-permease	unknown	unknown	gnl\|CDD\|238537
NZ_AP018111.1\|WP_096472142.1\|2317008_2317809_-\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|270231
NZ_AP018111.1\|WP_096472147.1\|2328958_2330611_-\|acyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|183199
NZ_AP018111.1\|WP_047899458.1\|2312240_2313635_+\|F0F1-ATP-synthase-subunit-beta	unknown	unknown	gnl\|CDD\|236447
NZ_AP018111.1\|WP_096472144.1\|2322140_2326073_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|236989
NZ_AP018111.1\|WP_096472148.1\|2330731_2331400_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_AP018111.1\|WP_096472143.1\|2317925_2319053_+\|uroporphyrinogen-decarboxylase	unknown	unknown	gnl\|CDD\|234644
NZ_AP018111.1\|WP_096472146.1\|2327408_2328917_-\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|341286
NZ_AP018111.1\|WP_047899457.1\|2311299_2312175_+\|F0F1-ATP-synthase-subunit-gamma	unknown	unknown	gnl\|CDD\|235535
NZ_AP018111.1\|WP_006751767.1\|2308631_2309102_+\|F0F1-ATP-synthase-subunit-B	unknown	unknown	gnl\|CDD\|180240
NZ_AP018111.1\|WP_096472139.1\|2309104_2309644_+\|F0F1-ATP-synthase-subunit-delta	unknown	unknown	gnl\|CDD\|235593
NZ_AP018111.1\|WP_096473113.1\|2319501_2321763_+\|primosomal-protein-N'	unknown	unknown	gnl\|CDD\|235514
NZ_AP018111.1\|WP_011546803.1\|2304070_2304964_+\|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl\|CDD\|275105
NZ_AP018111.1\|WP_096472145.1\|2326157_2327297_+\|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380565
NZ_AP018111.1\|WP_006482730.1\|2308232_2308502_+\|F0F1-ATP-synthase-subunit-C	unknown	unknown	gnl\|CDD\|180739
NZ_AP018111.1\|WP_096472140.1\|2309688_2311230_+\|F0F1-ATP-synthase-subunit-alpha	unknown	unknown	gnl\|CDD\|236448

Protein	Function_ID	Function_description	E-value
NZ_AP018111.1\|WP_096472141.1\|2314542_2316270_+\|AMP-binding-protein	gnl\|CDD\|236236	PRK08315, PRK08315, AMP-binding domain protein; Validated.	0
NZ_AP018111.1\|WP_006477288.1\|2313875_2314301_+\|F0F1-ATP-synthase-subunit-epsilon	gnl\|CDD\|234796	PRK00571, atpC, F0F1 ATP synthase subunit epsilon; Validated.	2.93721e-63
NZ_AP018111.1\|WP_034183834.1\|2307305_2308157_+\|F0F1-ATP-synthase-subunit-A	gnl\|CDD\|235617	PRK05815, PRK05815, F0F1 ATP synthase subunit A; Validated.	9.54569e-73
NZ_AP018111.1\|WP_096472138.1\|2306671_2307196_+\|ATP-synthase-subunit-I	gnl\|CDD\|377159	pfam03899, ATP-synt_I, ATP synthase I chain. The atp operon of alkaliphilic Bacillus pseudofirmus OF4, as in most prokaryotes, contains the eight structural genes for the F-ATPase (ATP synthase), which are preceded by an atpI gene that encodes a membrane protein with 2 TMSs. A tenth gene, atpZ, has been found in this operon, which is upstream of and overlapping with atpI. AtpI is a Ca2+/Mg2+ transporter.	3.47652e-13
NZ_AP018111.1\|WP_096472137.1\|2304974_2306105_+\|anion-permease	gnl\|CDD\|238537	cd01117, YbiR_permease, Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate sodium, sulfate, arsenite and organic anions. A typical ArsB/NhaD permease is composed of 8-13 transmembrane domains.	3.31901e-62
NZ_AP018111.1\|WP_096472142.1\|2317008_2317809_-\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|270231	cd01069, PBP2_PheC, Cyclohexadienyl dehydratase, a member of the type 2 periplasmic binding fold protein superfamily. This subfamily includes cyclohexadienyl dehydratase PheC. These proteins catalyze the decarboxylation of prephenate to phenylpyruvate in the alternative phenylalanine biosynthesis pathway in some proteobacteria and archaea. The PheC proteins belong to the PBPII superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. Since they the PheC proteins are so similar to periplasmic binding proteins, (PBP), it is evolutionarily plausible that several pre-existing PBP proteins might have been recruited to perform the enzymatic function.	2.50184e-123
NZ_AP018111.1\|WP_096472147.1\|2328958_2330611_-\|acyl-CoA-dehydrogenase-family-protein	gnl\|CDD\|183199	PRK11561, PRK11561, isovaleryl CoA dehydrogenase; Provisional.	3.99482e-175
NZ_AP018111.1\|WP_047899458.1\|2312240_2313635_+\|F0F1-ATP-synthase-subunit-beta	gnl\|CDD\|236447	PRK09280, PRK09280, F0F1 ATP synthase subunit beta; Validated.	0
NZ_AP018111.1\|WP_096472144.1\|2322140_2326073_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	gnl\|CDD\|236989	PRK11809, putA, trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed.	0
NZ_AP018111.1\|WP_096472148.1\|2330731_2331400_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.23346e-08
NZ_AP018111.1\|WP_096472143.1\|2317925_2319053_+\|uroporphyrinogen-decarboxylase	gnl\|CDD\|234644	PRK00115, hemE, uroporphyrinogen decarboxylase; Validated.	0
NZ_AP018111.1\|WP_096472146.1\|2327408_2328917_-\|AMP-binding-protein	gnl\|CDD\|341286	cd17631, FACL_FadD13-like, fatty acyl-CoA synthetase, including FadD13. This family contains fatty acyl-CoA synthetases, including Mycobacterium tuberculosis acid-induced operon MymA encoding the fatty acyl-CoA synthetase FadD13 which is essential for virulence and intracellular growth of the pathogen. The fatty acyl-CoA synthetase activates lipids before entering into the metabolic pathways and is also involved in transmembrane lipid transport. However, unlike soluble fatty acyl-CoA synthetases, but like the mammalian integral-membrane very-long-chain acyl-CoA synthetases, FadD13 accepts lipid substrates up to the maximum length of C26, and this is facilitated by an extensive hydrophobic tunnel from the active site to a positively charged patch. Also included is feruloyl-CoA synthetase (Fcs) in Rhodococcus strains where it is involved in biotechnological vanillin production from eugenol and ferulic acid via a non-beta-oxidative pathway.	1.17451e-168
NZ_AP018111.1\|WP_047899457.1\|2311299_2312175_+\|F0F1-ATP-synthase-subunit-gamma	gnl\|CDD\|235535	PRK05621, PRK05621, F0F1 ATP synthase subunit gamma; Validated.	5.44502e-157
NZ_AP018111.1\|WP_006751767.1\|2308631_2309102_+\|F0F1-ATP-synthase-subunit-B	gnl\|CDD\|180240	PRK05759, PRK05759, F0F1 ATP synthase subunit B; Validated.	3.71441e-56
NZ_AP018111.1\|WP_096472139.1\|2309104_2309644_+\|F0F1-ATP-synthase-subunit-delta	gnl\|CDD\|235593	PRK05758, PRK05758, F0F1 ATP synthase subunit delta; Validated.	2.99955e-66
NZ_AP018111.1\|WP_096473113.1\|2319501_2321763_+\|primosomal-protein-N'	gnl\|CDD\|235514	PRK05580, PRK05580, primosome assembly protein PriA; Validated.	0
NZ_AP018111.1\|WP_011546803.1\|2304070_2304964_+\|ParB/RepB/Spo0J-family-partition-protein	gnl\|CDD\|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	7.68465e-78
NZ_AP018111.1\|WP_096472145.1\|2326157_2327297_+\|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380565	cd06342, PBP1_ABC_LIVBP-like, type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine). This subgroup includes the type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine). This subgroup also includes a leucine-specific binding protein (or LivK), which is very similar in sequence and structure to leucine-isoleucine-valine binding protein (LIVBP). ABC-type active transport systems are transmembrane proteins that function in the transport of diverse sets of substrates across extra- and intracellular membranes, including carbohydrates, amino acids, inorganic ions, dipeptides and oligopeptides, metabolic products, lipids and sterols, and heme, to name a few.	2.54839e-141
NZ_AP018111.1\|WP_006482730.1\|2308232_2308502_+\|F0F1-ATP-synthase-subunit-C	gnl\|CDD\|180739	PRK06876, PRK06876, F0F1 ATP synthase subunit C; Validated.	1.89688e-24
NZ_AP018111.1\|WP_096472140.1\|2309688_2311230_+\|F0F1-ATP-synthase-subunit-alpha	gnl\|CDD\|236448	PRK09281, PRK09281, F0F1 ATP synthase subunit alpha; Validated.	0

>NZ_AP018111.1|WP_047899458.1|2312240_2313635_+|F0F1-ATP-synthase-subunit-beta
MSTAALVEGKIVQCIGAVIDVEFPRDSMPKIYDALILDGSELTLEVQQQLGDGVVRTICLGASDGLRRGLTVKNTANPISVPVGKPTLGRIMDVLGRPIDEAGPIVSETTRSIHQKAPAFDELSPSTELLETGIKVIDLICPFAKGGKVGLFGGAGVGKTVNMMELINNIAKEHGGYSVFAGVGERTREGNDFYHEMKDSNVLDKVALVYGQMNEPPGNRLRVALTGLTMAEHFRDEGLDVLFFVDNIYRFTLAGTEVSALLGRMPSAVGYQPTLAEEMGKLQERITSTKKGSITSVQAVYVPADDLTDPSPATTFGHLDATVVLSRDIASLGIYPAVDPLDSTSRQIDPNVIGEEHYSITRRVQQTLQRYKELRDIIAILGMDELSPEDKLSVARARKIQRFLSQPFHVAEVFTGSPGKYVPLKETIRGFKMIVDGECDHLPEQAFYMVGTIDEAFEKAKKIQ
>NZ_AP018111.1|WP_047899457.1|2311299_2312175_+|F0F1-ATP-synthase-subunit-gamma
MAGMKEIRGKIKSVQNTRKITKAMEMVAASKMRRAQERMRAARPYADKVRAIAAHMSRANPEYRHPFMVANDGANTAGIILVTTDKGLCGGLNTNVLRATVQKFKELEEKGQKVEATAIGSKGLGFLNRFGAKVLSQVVHLGDTPHLDKLIGAVKTQLDLYSEGKLSAVYIAYTRFVNTMKQEAVIEQLLPLSSEHFEADDGTPATSWDYIYEPDAQAVVDELLVRYVEALVYQAVAENMASEQSARMVAMKAASDNAKTVISELQLVYNKSRQAAITKELSEIVGGAAAV
>NZ_AP018111.1|WP_096472140.1|2309688_2311230_+|F0F1-ATP-synthase-subunit-alpha
MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSDVMQGEMLEFPGNTFGLALNLERDSVGAVILGEYEHISEGDVVKTTGRILEVPVGPELVGRVVDALGNPIDGKGPVNAKLTDAIEKIAPGVIWRKSVSQPVQTGIKSIDAMVPIGRGQRELIIGDRQCGKTAVALDAIINQKGKDLICIYVAIGQKASSIMNVVRKLEETGAMEYTIVVAATASDSAAMQYLAPYAGCTMGEYFRDRGQDALIIYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTNGEVKGKSGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLFNAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQYRELAAFAQFASDLDEATRKQLERGRRVTELLKQPQYQPLQVWELAVSLYAANNGYLDDLDVKQVLSFEKGLRESLKTSNADLIKRIEDTKDLSKDDEGALRSAIESFKKSGAY
>NZ_AP018111.1|WP_096472139.1|2309104_2309644_+|F0F1-ATP-synthase-subunit-delta
MAELATIARPYAEALFRVAEGGDIAAWSTLVQELAQVAHLPEVLSVASSPKVTRTQVAELLLAAVKSPLAAGAEAKNFVQMLVDNHRIALLPEIAEQFEALKNEREGAADAEIVSAFPLNGTDLESLVSGLERKFKRKLKPTVEVDSSLIGGVRVTVGDEVLDTSVRARLASMQAALTA
>NZ_AP018111.1|WP_006751767.1|2308631_2309102_+|F0F1-ATP-synthase-subunit-B
MNLNATLFAQMVVFLVLAWFTMKFVWPPLINALDERSKKIADGLAAAEKGKAELDAAHKRVDQELAQARNDGQQRIADAEKRAQAVAEEIKANAQAEAARIVAQAKAEAEQQIVKAREALRGEVASLAVKGAEQILKREVDQTAHAQLLNQLKAEL
>NZ_AP018111.1|WP_006482730.1|2308232_2308502_+|F0F1-ATP-synthase-subunit-C
MQAYIANIQGLTAIGIGIIIGLGAIGACIGIALMGGKYIEACARQPELINPLQTKMFLLAGLIDAAFLIGVGVAMLFAFANPLLSKLAG
>NZ_AP018111.1|WP_034183834.1|2307305_2308157_+|F0F1-ATP-synthase-subunit-A
MAASEGTRGPDPSEYIAHHLQNFSTSHQTSIFDIHVWNLDTLFWSIVCGIVTILLLRLAARKATSGVPGRFQCAIEMLVEMVEDQSKAIVHGNRTFIAPLALTVFVWVALMNSLDFLPVDLPGRVIGLLGLSDVISHHRIVPTADLNGTLGIALGVFVLMIYYSIKIKGAGGFVHELLSAPFGAHPLLWIPNLALNIVEYLAKTVSLGMRLFGNMYAGELLFLLIALLGSMWSFGGDATFLGFVGHVIAGSVWAIFHILIVLLQAFIFMMLTLVYLGQAHDTH
>NZ_AP018111.1|WP_096472138.1|2306671_2307196_+|ATP-synthase-subunit-I
MAGQAPDDRHDDQRTQRTASAAGERRESDDDWDAEQQDNNIVPLTRADAERLFGPDVSKPSRVTPSKVVLAQVVLSLVATLAWWLFSKSPGAAAQSAFLGGAIGWVPSALFVARLKAGGSATVMSWVMGEALKLGLTVGMFAAVAFGWSGVHWVPFLVTYLVVLKTYWIALAWR
>NZ_AP018111.1|WP_096472137.1|2304974_2306105_+|anion-permease
MEKTGAPVPRRWLGWLAQEPVLSVLALGLIVLQWVRPQPFSVLAGRVDWQTVATLAGLLMLTKALELSGCLMWLAHRIVHHVHSERGLAMLLVVFAAVLSMWLTNDVALFVVVPLMVSLRALTPLPFRRLVIVVALAVNAGSVATPLGNPQNLFLWQLSGVSFGRFVVTLGPLAIALMVLLLALTACAFRAKPLDLSGDVVALPVQRMHALIAAVLFAAFVLLADAHHPLPGLVAVAIVLFVIKRDAVLKIDWLLLLIFVLMFVVLRSAAALPVVHDAIARAHLDSPLRVFAAGAVLSQGISNVPAAILLSEFTHDWRALAFGVSVGGFGFAIGSLANLIAVRLAKEPRMWLPFHLVSIPFALVSAALGAWLLVHG
>NZ_AP018111.1|WP_011546803.1|2304070_2304964_+|ParB/RepB/Spo0J-family-partition-protein
MNAVPKKKGLGRGLEALLGGSADITEAVKIEGAPNTLALGKLQAGKYQPRTRMDEGSLQELAASIRAQGVMQPILVRPISSDKYEIIAGERRFRAARLAGLDEVPVLVKDVSDQAAAAMALIENIQREDLNPLEEAHGIQRLLDEFGFTHEQAAESVGRSRSAVSNLLRLLNLASPVQTMLLAGDLDMGHARALLAVDAATQITLAHQVVNKRMSVRETEKLVSHTTKEAPAVKARAKDDGGRDTRRLEEELSDLLASTVKIKLGRRGRGQVLIDFGNLDALEGILARLRGNVATEE
>NZ_AP018111.1|WP_006477288.1|2313875_2314301_+|F0F1-ATP-synthase-subunit-epsilon
MATIKVDVVSAEEQIFSGEAKFVALPGETGELGILPGHTPLITRIRPGAVRIEVEGGNDEFVFVAGGILEVQPGAVTVLADTAIRGKDLDAAKAEEARKRAEETLQNAKSDLDLAKAQSELATAMAQLEAIQRLAKIRSRH
>NZ_AP018111.1|WP_096472141.1|2314542_2316270_+|AMP-binding-protein
MAADLGVGALIAPENGLSYVRGATDVPLSEATIGRFLRDTAGRFPDRPAVVFREQQVRWTWREFANEVDVLAAGLAALGIVKGDCVGIWSPNRSEWLLTQFATARIGAVLVNINPAYRLSELEYALNKVGCKAVIAAERFKSSAYVEMLQTIAPELATATPGDLHAARVPSLRTVVSMGDVAPAGMFRFADVMTRGRQAVDPALLDAIGATLKATDAINIQFTSGTTGSPKGATLTHRNVVNNARSIAMAMRFTEQDSLCIPVPLYHCFGMVLAVLACVSKGAAMVFPGEAFDPVATLAAVADERCTALHGVPTMFIAELDHPEFPKFDLSTLRTGIMAGSPCPIETMKRVVSQMHLSEITIAYGMTETSPVSFQSSTDDPLEKRTTTVGRIQPHLEVKIVDPNGEIVPVGATGELCTKGYSVMLGYWDDDAKTREVLVDGWMHTGDLATLDADGYCNIVGRLKDMVIRGGENVYPREIEEFLFRHPKIQSAQVFGVPDAKYGEELCAWIVLRADEQMTEDDVRAFCNGQIAHYKIPRYIRFVDELPMTVTGKVQKFVMRDRMIEELKLDVQKTA
>NZ_AP018111.1|WP_096472142.1|2317008_2317809_-|transporter-substrate-binding-domain-containing-protein
MKTFATLAAAALLCCAAAHAQTGVGAAAAAPGAGSRLDDVLARGALRVCTTGDYKPYSYYRADGRFEGIDIDMAESLAKSLGVKTDYVKTSWSNLTGDFVAKCDIAVGGVSTTLERQKRVFFTQPYVVDGKTPIARCADADKYQTVAQIDRPETRVIVNPGGTNERFAKQYFTHANLSVYPDNVTIFKQILAGKADVMVTDASETLLQQKLNPGLCSVHPDKPFQFGEKAYMVPRGDVAFQQYVDQWLHLALSTGEYQAISDKWLK
>NZ_AP018111.1|WP_096472143.1|2317925_2319053_+|uroporphyrinogen-decarboxylase
MPLCPRIVAPTVAHNLLNDTFLRALLREPTDYTPIWLMRQAGRYLPEYNATRARAGSFLGLAKNPDYATEVTLQPLERFPLDAAILFSDILTIPDAMGLGLDFQVGEGPKFAHPVRTEADVAKLAVPDIEATLGYVTGAVREIRRALTDGQGRQRVPLIGFSGSPWTLACYMVEGGGSDDFRTVKSMAYSRPDLMHRILDVNAQAVAAYLNAQIEAGAQAVMIFDTWGGALADGAYQRFSLDYIRRVVAQLKREHDGERVPVITFTKGGGLWLEEIAATGVDAVGLDWTVNLGAARERVAGRVALQGNLDPTILFAPPAAVREQARAVLDSYGNHPGHVFNLGHGISQFTSPDHVAELVDEVHNHSRAIRSGAAG
>NZ_AP018111.1|WP_096473113.1|2319501_2321763_+|primosomal-protein-N'
MDGTYLRVALDHPLATLFDYRCDAQPAPVPGTLVQVPFGKRQAVGLVCEVTTHTDVPPSRLRAIDAICTDLPPLSADWLALVSFAADYYQRGRGEVALPALPQALRDAGRWGRLLAPEVRYRPTEAGRAALPDALPARGAALRRLAQALVDTGSLGLPDARALHPKAAATLDDWAARGWVDVEEIGWADAPVPKAVDNLSTTGGRAVPPALTDQQAEALDAIRAAQGFAPFLLHGVTGSGKTEVYLHALASLLDARPDAQALVLVPEINLTPQFEAAFRARFAGALADDAIVTLHSGLAEGERARNWLAAHTGRARIVLGTRLAVLASMPALALVVVDEEHEPAYKQQEGLRYSARDLAVWRAKQLGITVVLGSATPSLESWWQAEQGRYTRLTLSRRAVADATLPTVRLIDLEEERRRGRASMGGLSGPLVAALKARLERGEQSLVFLNRRGYAPQLACDACGWVAGCPRCSAYVVLHKPEHALRCHHCGWEARIPRSCPECGNVDIAPLGRGTQRIEEALAEAVPGARVLRIDADSTRRKGSAQALFSDVHAGEVDILVGTQMIAKGHDFQRVSLVGVLNADTALFSHDFRASERLFAQLMQVSGRAGRAGLPGEVMVQTRYPRHALYHALGRQDYVGFANSTLGERRDAHLPPFVYQALLRAEGRTLDAALAFLLQAAAALPGLPGADRVTVYDAVPMTIVKVANVHRAQLLLESASRAALQHALRAWQPELRALKGVLRWSVEVDPLDI
>NZ_AP018111.1|WP_096472144.1|2322140_2326073_+|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase
MASTTLGVKVDDLLRSRLKDAAARLERTPHWLIKQAIFAYLERIEHGQLPPELSGHSGVTELADGQAADGDDDNSPHPFLEFAQNVQPQSVLRAAITAAYRRPEPECVPFLLGQARLPANLQADAQALATKLVEALREKSSGGGVEGLIHEFSLSSQEGVALMCLAEALLRIPDRATRDALIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGRGGEPLIRKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDAQRYYASYEQAIHAIGKAAGGRGIYEGPGISIKLSALHARYSRSQQDRTMSELLPRVRSLALLARRYDIGLNIDAEEADRLELSLDLLEALCFDQDLAGWNGIGFVVQGYQKRCPFVIDYLIDLARRSRHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQFATHNAYTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSFVNRIADKSVSVKELVADPVDEAMKVVPLGAPHAKIPLPRNLYGDERPNSMGLDLSNEHRLASLSSALLASAHFPWRAAPMLADDALADAPARDVRNPADQRDAVGTVSEATAEHVSAALAHAVAAAPIWQATPVDARADCLVRAADLLEAQMHTLMGLIVREAGKSLPNAIAEIREAVDFLRYYAAQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPLIAAQAVRLLREAGVPAGAVQLLPGDGETVGAALVADPRTRAVMFTGSTEVARLINKTLAARLDPDGKPIPLIAETGGQNAMIVDSSALAEQVVADVMQSSFDSAGQRCSALRVLCLQDDVADRTLTMLKGAMHELALGNPDRLSTDVGPVIDGEAKQTIDTHVAAMKDKGHAVTQLPAPDACAHGTFVPPTLIEIGSIDELKREVFGPVLHVVRYRRSQLDKLLEQIRATGYGLTLGIHTRIDETIAHVISNAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPSGLPRSLAQTLMADGAVEGDARGNPAAALTTLRDWLIEQREPVLAARCDGYLAQVPAGATAVLTGPTGERNTYTLGPRGTVLCVAATPGGARAQFAAVLATGNRALFAGAAGEALVAALPASLKAHAAVRKQADVAFDAVLFEGDSDELQTLVKDVAQRPGPIVSVQGVSVGAFENGDAEDYALERLLTERSVSVNTAAAGGNANLMTIG
>NZ_AP018111.1|WP_096472145.1|2326157_2327297_+|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein
MQHTMKKVAGATFVAVMSLAGTAHADDVKIGYAGPMTGAQAHYGKDMQNGIVLALEDFNATNPKIGGKPVKFVLNTQDDQADPRTGTTVAQKLVDDGIKGMLGHFNSGTTIPASRIYANAGIPEIAMATAPEYTQQGYKTTFRMMTSDTQQGSVAGTFASKDLGMKKIAIVDDRTAYGQGLADQFEKAAKAGGATIVDREFTNDKAVDFKAILTKLKSAKPDLVYYGGADSQAAPMVKQMKALGIAAPLMSGEMVKTPTFLKIAGNASEGTIASLAGLPLEEMPGGKAYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKADSTDPAKYLPVLAKSDMAGVTSTHVAYDAKGDLKNGGITMYKVEKGEWKPLKSIGGK
>NZ_AP018111.1|WP_096472146.1|2327408_2328917_-|AMP-binding-protein
MNLVAALDRAARATPDKPFLVSESATITYAAARERSHRAAAVLSALGIAAGDRVAAMCFNTPAFVDLMFGAWRLGATFVPVNHKLQAPEVDYVLEHSRSKVLLFDVALAPVVERIVHPARRLVTEGELDGVPCFDTMCATMDGVAGIEPADGDIAQILYTSGTTGRPKGCVHSHRTVTLAAMSAALATGIGRNERTLMAMPIWHSSPLNNWFGGTLVAGGTVVLLREYHPLRFLQTVERERVTLYFGAPVSYTLPLDTIDGFAAFDLSSVRAWLYGGGPIGAAQAERLARAYRSDAFFQVYGMTETGPAGTTLYPDEQIAKAGSIGRHGGPGVDLRVVRMDGIDARPGETGEIWLKADSMMLGYLDDANATRAAFAPGGWYRTGDIARIDQDRYLFIVDRLKDMIVTGGENVYSKEVEDVLGAHPDIAEAAVVGVPHPDWGETVVAHVVMRAGTVPDADALRAFCGERLAAYKIPREFAFAQALPRTPTGKLQKFLLRVRKE
>NZ_AP018111.1|WP_096472147.1|2328958_2330611_-|acyl-CoA-dehydrogenase-family-protein
MTESTHAVTNQFDELVDYNLFATDIALRDALARAGADWAVPQLDAYGARLGSADTAQLADEANQHTPELHTFDRRGRRIDRVDFHPAWHALLGQYRHEGFVSLAFRDARRGRWAATAAGFYLHGQIEAGTLCPATMTQAAIPVLQKEPALWSLLRDKLYSDDYDPRDVPVADKRSIWFGMGMTEKQGGSDVRANTTLATAVGAGGRGGEYLLRGHKWFFSAPMCDAHLVVAHTEGGSPSCFYVPRWRPDGTKNAVEIQRLKNKVGNRSNSSSEIELNDAWGIMLGDEGRGIPTIIEMATYTRLNCVLGSAAMLRQGVVQAIAYTRQRHAFGRALAEQPLMRTVLADLALESEAALALAMRLADAFERDDSPRERAWKRIVTPAAKFWVCKRAVELTGEVMEVFGGNGYVDDGPIARLFREAPVNSIWEGSGNVMCLDVLRAVSREPDSAAALFAELADLGAGEPRIRAALDALRAMLAAPADTLEASGRVFAQRLAIVAQACLLRRDAPAAVADAFVATRLAAPDWGRIAGGFDPHALDVAALLQRAYPA
>NZ_AP018111.1|WP_096472148.1|2330731_2331400_+|TetR/AcrR-family-transcriptional-regulator
MPPRHVQVPAPPGQPAAQPAPALRRRPRQSRAQASSDALQQAFVQLLLERGYAKATIREIAAVAGVSIGTFYEYFGDKQSLAALCIHRYVQAMADRLRDAAERLRGAQRAELAVALVDLQVDAIGADAALWSALFALERQVSPLAAYRRHYDAYVALWRDALAHAADPPPAARLDGLARMAHTVCYGGLSQALLTLGPALDFAALRGELRAVLLAYLAAAGA

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Crispr_ID: NZ_AP018111_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP018111_5

2336405-2336584

Orphan

Consensus_repeat	Method
CACGACCACGACCACGACCACGAC	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_AP018111_5

>merge|NZ_AP018111|5|2336405-2336584|CRISPRCasFinder
CGCGGCCACGACCATGATCACGGTCACGGCGGTGGTGAAGGGCACGATCACGATCATGCACACGGCGACGCGCATGCACACGGCGCGGCGTGTTCGCACGACCACGCCGCGCATGACCATGCCGGTCACGACCACGACCACGACCACGACCACGACCACGACCACGACCACGACCACGAC

>NZ_AP018111|5|4|2336405-2336584|CRISPRCasFinder
CGCGGCCACGACCATGATCACGGT	CACGGCGGTGGTGAAGGG
CACGATCACGATCATGCACACGGC	GACGCGCATGCACACGGCGCGGCGTGTTCGCACGACCACGCCGCGCAT
GACCATGCCGGTCACGACCACGAC	CACGACCACGACCACGAC
CACGACCACGACCACGACCACGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP018111.1\|WP_096472158.1\|2344987_2345782_+\|ethanolamine-ammonia-lyase-subunit-EutC	unknown	unknown	gnl\|CDD\|235482
NZ_AP018111.1\|WP_096472157.1\|2343593_2344991_+\|ethanolamine-ammonia-lyase-subunit-EutB	unknown	unknown	gnl\|CDD\|237897
NZ_AP018111.1\|WP_011546785.1\|2335741_2336173_-\|Cd(II)/Pb(II)-responsive-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133411
NZ_AP018111.1\|WP_096472160.1\|2346852_2348463_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_AP018111.1\|WP_096472146.1\|2327408_2328917_-\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|341286
NZ_AP018111.1\|WP_096472147.1\|2328958_2330611_-\|acyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|183199
NZ_AP018111.1\|WP_096472156.1\|2342089_2343502_+\|ethanolamine-permease	unknown	unknown	gnl\|CDD\|129986
NZ_AP018111.1\|WP_034183849.1\|2332820_2333609_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270421
NZ_AP018111.1\|WP_096472154.1\|2339284_2340163_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|336409
NZ_AP018111.1\|WP_096472148.1\|2330731_2331400_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_AP018111.1\|WP_096472159.1\|2345812_2346697_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176165
NZ_AP018111.1\|WP_096472149.1\|2331611_2332766_+\|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl\|CDD\|183514
NZ_AP018111.1\|WP_096472150.1\|2333624_2335055_+\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NZ_AP018111.1\|WP_096472162.1\|2349407_2350934_+\|aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143434
NZ_AP018111.1\|WP_096472153.1\|2338829_2339204_+\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|372305
NZ_AP018111.1\|WP_096472145.1\|2326157_2327297_+\|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380565
NZ_AP018111.1\|WP_096472151.1\|2335100_2335673_-\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609
NZ_AP018111.1\|WP_096472161.1\|2348648_2349125_-\|pyridoxamine-5'-phosphate-oxidase-family-protein	unknown	unknown	gnl\|CDD\|274926
NZ_AP018111.1\|WP_096472155.1\|2340439_2341903_+\|mechanosensitive-ion-channel	unknown	unknown	gnl\|CDD\|377524
NZ_AP018111.1\|WP_096472144.1\|2322140_2326073_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|236989

Protein	Function_ID	Function_description	E-value
NZ_AP018111.1\|WP_096472158.1\|2344987_2345782_+\|ethanolamine-ammonia-lyase-subunit-EutC	gnl\|CDD\|235482	PRK05465, PRK05465, ethanolamine ammonia-lyase subunit EutC.	1.36022e-138
NZ_AP018111.1\|WP_096472157.1\|2343593_2344991_+\|ethanolamine-ammonia-lyase-subunit-EutB	gnl\|CDD\|237897	PRK15067, PRK15067, ethanolamine ammonia-lyase subunit EutB.	0
NZ_AP018111.1\|WP_011546785.1\|2335741_2336173_-\|Cd(II)/Pb(II)-responsive-transcriptional-regulator	gnl\|CDD\|133411	cd04784, HTH_CadR-PbrR, Helix-Turn-Helix DNA binding domain of the CadR and PbrR transcription regulators. Helix-turn-helix (HTH) CadR and PbrR transcription regulators including Pseudomonas aeruginosa CadR and Ralstonia metallidurans PbrR that regulate expression of the cadmium and lead resistance operons, respectively. These proteins are comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the C-terminal domains have three conserved cysteines which form a putative metal binding site. Some members in this group have a histidine-rich C-terminal extension. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	7.7259e-63
NZ_AP018111.1\|WP_096472160.1\|2346852_2348463_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	4.35849e-34
NZ_AP018111.1\|WP_096472146.1\|2327408_2328917_-\|AMP-binding-protein	gnl\|CDD\|341286	cd17631, FACL_FadD13-like, fatty acyl-CoA synthetase, including FadD13. This family contains fatty acyl-CoA synthetases, including Mycobacterium tuberculosis acid-induced operon MymA encoding the fatty acyl-CoA synthetase FadD13 which is essential for virulence and intracellular growth of the pathogen. The fatty acyl-CoA synthetase activates lipids before entering into the metabolic pathways and is also involved in transmembrane lipid transport. However, unlike soluble fatty acyl-CoA synthetases, but like the mammalian integral-membrane very-long-chain acyl-CoA synthetases, FadD13 accepts lipid substrates up to the maximum length of C26, and this is facilitated by an extensive hydrophobic tunnel from the active site to a positively charged patch. Also included is feruloyl-CoA synthetase (Fcs) in Rhodococcus strains where it is involved in biotechnological vanillin production from eugenol and ferulic acid via a non-beta-oxidative pathway.	1.17451e-168
NZ_AP018111.1\|WP_096472147.1\|2328958_2330611_-\|acyl-CoA-dehydrogenase-family-protein	gnl\|CDD\|183199	PRK11561, PRK11561, isovaleryl CoA dehydrogenase; Provisional.	3.99482e-175
NZ_AP018111.1\|WP_096472156.1\|2342089_2343502_+\|ethanolamine-permease	gnl\|CDD\|129986	TIGR00908, putative_ethanolamine_permease, ethanolamine permease. The three genes used as the seed for this model (from Burkholderia pseudomallei, Pseudomonas aeruginosa and Clostridium acetobutylicum are all adjacent to genes for the catabolism of ethanolamine. Most if not all of the hits to this model have a similar arrangement of genes. This group is a member of the Amino Acid-Polyamine-Organocation (APC) Superfamily. [Transport and binding proteins, Amino acids, peptides and amines].	0
NZ_AP018111.1\|WP_034183849.1\|2332820_2333609_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270421	cd13703, PBP2_HisJ_LAO, Substrate binding domain of ABC-type histidine- and lysine/arginine/ornithine transporters; the type 2 periplasmic-binding protein fold. This subgroup includes the periplasmic-binding proteins, HisJ and LAO, that serve as initial receptors in the ABC transport of histidine and lysine-arginine-ornithine amino acids. They are belong to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.04785e-114
NZ_AP018111.1\|WP_096472154.1\|2339284_2340163_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|336409	pfam06445, GyrI-like, GyrI-like small molecule binding domain. This family contains the small molecule binding domain of a number of different bacterial transcription activators. This family also contains DNA gyrase inhibitors. The GyrI superfamily contains a diad of the SHS2 module, adapted for small-molecule binding. The GyrI superfamily includes a family of secreted forms that is found only in animals and the bacterial pathogen Leptospira.	2.73171e-37
NZ_AP018111.1\|WP_096472148.1\|2330731_2331400_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.23346e-08
NZ_AP018111.1\|WP_096472159.1\|2345812_2346697_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176165	cd08476, PBP2_CrgA_like_7, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold. This CD represents the substrate binding domain of an uncharacterized LysR-type transcriptional regulator (LTTR) CrgA-like 7. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	6.24915e-117
NZ_AP018111.1\|WP_096472149.1\|2331611_2332766_+\|pyridoxal-phosphate-dependent-aminotransferase	gnl\|CDD\|183514	PRK12414, PRK12414, putative aminotransferase; Provisional.	0
NZ_AP018111.1\|WP_096472150.1\|2333624_2335055_+\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	8.22346e-98
NZ_AP018111.1\|WP_096472162.1\|2349407_2350934_+\|aldehyde-dehydrogenase	gnl\|CDD\|143434	cd07116, ALDH_ACDHII-AcoD, Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like. Included in this CD is the NAD+-dependent, acetaldehyde dehydrogenase II (AcDHII, AcoD, EC=1.2.1.3) from Ralstonia (Alcaligenes) eutrophus H16 involved in the catabolism of acetoin and ethanol, and similar proteins, such as, the dimeric dihydrolipoamide dehydrogenase of the acetoin dehydrogenase enzyme system of Klebsiella pneumonia. Also included are sequences similar to the NAD+-dependent chloroacetaldehyde dehydrogenases (AldA and AldB) of Xanthobacter autotrophicus GJ10 which are involved in the degradation of 1,2-dichloroethane. These proteins apparently require RpoN factors for expression.	0
NZ_AP018111.1\|WP_096472153.1\|2338829_2339204_+\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|372305	pfam12773, DZR, Double zinc ribbon. This family consists of a pair of zinc ribbon domains.	1.27198e-10
NZ_AP018111.1\|WP_096472145.1\|2326157_2327297_+\|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380565	cd06342, PBP1_ABC_LIVBP-like, type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine). This subgroup includes the type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine). This subgroup also includes a leucine-specific binding protein (or LivK), which is very similar in sequence and structure to leucine-isoleucine-valine binding protein (LIVBP). ABC-type active transport systems are transmembrane proteins that function in the transport of diverse sets of substrates across extra- and intracellular membranes, including carbohydrates, amino acids, inorganic ions, dipeptides and oligopeptides, metabolic products, lipids and sterols, and heme, to name a few.	2.54839e-141
NZ_AP018111.1\|WP_096472151.1\|2335100_2335673_-\|PadR-family-transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	1.59376e-09
NZ_AP018111.1\|WP_096472161.1\|2348648_2349125_-\|pyridoxamine-5'-phosphate-oxidase-family-protein	gnl\|CDD\|274926	TIGR04025, hypothetical_protein, PPOX class probable FMN-dependent enzyme, DR_2398 family. Members of the PPOX family (see pfam01243) may contain either FMN or F420 as cofactor. This subfamily consists of proteins mostly from species that lack the capability to synthesize F420, and therefore most likely all bind FMN.	2.01806e-17
NZ_AP018111.1\|WP_096472155.1\|2340439_2341903_+\|mechanosensitive-ion-channel	gnl\|CDD\|377524	pfam05552, TM_helix, Conserved TM helix. This alignment represents a conserved transmembrane helix as well as some flanking sequence. It is often found in association with pfam00924.	9.49026e-10
NZ_AP018111.1\|WP_096472144.1\|2322140_2326073_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	gnl\|CDD\|236989	PRK11809, putA, trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed.	0

>NZ_AP018111.1|WP_011546785.1|2335741_2336173_-|Cd(II)/Pb(II)-responsive-transcriptional-regulator
MKIGELAKAARCTPETIRFYEKEGLMPDAERTDSNYRNYTDVHVERLRFIRNCRALDMAHDEIRALLQLTDTPADRCDSINSLLDDHIGHVDARLAELTHLRDQLTELRRQCVGEHSVEDCGIVHGLATMETVAPAAKRSHLG
>NZ_AP018111.1|WP_096472151.1|2335100_2335673_-|PadR-family-transcriptional-regulator
MSTSRPSPLALAVLATLTETPMHPYGMLQQLKARGYDEVVNVRQRTSLYQTIDRLLRDGLIAVHDTERDGAFPERTLYALTEAGHTAGQTWLHALLAEPAREFPVFGAGLAFLPLLDAEDARHQLELRIARLDAERERLEALRNAAQADQVPRLFLLQNEHALVLLNAELDWARSVVEHLKIGALRWVDG
>NZ_AP018111.1|WP_096472150.1|2333624_2335055_+|FAD-binding-oxidoreductase
MPNPNPAATGGEQDGAPLSDDALDAVLAAELGDALVTRAADIDPRYFTAYNEPAGVRPRALVRPRSVDDVSRTLALCARLGQPVVPQGGLTGLARGAVALGGEVVLSMERFAGIEALDAAAGTMTVRAGTPLQTVQEAAEAAGFTFGVDLGARGSCQIGGMLATNAGGTRAIRYGMMREQVLGLEAVLADGTVVSSMNRMLKNNAGYDLKQLFIGSEGTLGIVTRAVLRLHPLLAAPATALCRVRDYDAVVGLWNRVRTLPEVVSFEAMWPAFYDYVARHTPGVTAPFAGDGGFAVLIECATSAPGGDAHQALENGLAAGIDAGLVDDAVLATSERQARDLWTLREGLAIDALPHLVNFDVSLPTGELGAFAERCEAALRSRWPGVTCLFFGHVGDGNVHIGVSLAGMTDADADALDHCVYAVVRDMGGSVSAEHGIGALKRPYLAHTRSDAEIGLMRRLKAALDPRGILNPGKVL
>NZ_AP018111.1|WP_034183849.1|2332820_2333609_+|ABC-transporter-substrate-binding-protein
MKHTATLKLAFALACAIGSGAALADTQTLRFGLEAQYPPFESKAPNGDLQGFDIDVGNAVCQTAKLSCKWVETSFDGLIPALKGRKFDAINSAMNATEQRRQAIDFTTIIYRVPTQLIARTGSGLLPTPESLKGKRVGVLQASIQETFAKAHWEPAGVAVVAYQDQNQAYADLVAGRLDATLVLAPSGQRGFLSRPDGKGFSFVGQPVHDDRILGSGIAFGLRKGDDALKAKLDAAIDKLKADGTVKSLGLKYFGDIDISTK
>NZ_AP018111.1|WP_096472149.1|2331611_2332766_+|pyridoxal-phosphate-dependent-aminotransferase
MRSATAPRSKLPDVGTTIFTVIGQLAAQHDALNLSQGAPNFAPDPALVEGVARAMRDGHNQYSPMAGVMALRERLAEKTEALYGARYDPATEITVIASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIKLSPEHFRVNWDEVAAAITPRTRMIIVNTPHNPTATVFSADDLERLAQLTRDTGIVILSDEVYEHVVFDGAQHQSVARHRELAERSVIVSSFGKSFHVTGWRVGHCLAPAELMDEIRKVHQFMVFAADTPMQVAFAEILARPDSYLGLSAFYQAKRDLLARELADSRFELLPSEGSFFMLARFRHFSNESDSDFVLRLIRDARVATIPLSAFYTDGTDAGVIRLSFSKDDATLVEGARRLRSL
>NZ_AP018111.1|WP_096472148.1|2330731_2331400_+|TetR/AcrR-family-transcriptional-regulator
MPPRHVQVPAPPGQPAAQPAPALRRRPRQSRAQASSDALQQAFVQLLLERGYAKATIREIAAVAGVSIGTFYEYFGDKQSLAALCIHRYVQAMADRLRDAAERLRGAQRAELAVALVDLQVDAIGADAALWSALFALERQVSPLAAYRRHYDAYVALWRDALAHAADPPPAARLDGLARMAHTVCYGGLSQALLTLGPALDFAALRGELRAVLLAYLAAAGA
>NZ_AP018111.1|WP_096472147.1|2328958_2330611_-|acyl-CoA-dehydrogenase-family-protein
MTESTHAVTNQFDELVDYNLFATDIALRDALARAGADWAVPQLDAYGARLGSADTAQLADEANQHTPELHTFDRRGRRIDRVDFHPAWHALLGQYRHEGFVSLAFRDARRGRWAATAAGFYLHGQIEAGTLCPATMTQAAIPVLQKEPALWSLLRDKLYSDDYDPRDVPVADKRSIWFGMGMTEKQGGSDVRANTTLATAVGAGGRGGEYLLRGHKWFFSAPMCDAHLVVAHTEGGSPSCFYVPRWRPDGTKNAVEIQRLKNKVGNRSNSSSEIELNDAWGIMLGDEGRGIPTIIEMATYTRLNCVLGSAAMLRQGVVQAIAYTRQRHAFGRALAEQPLMRTVLADLALESEAALALAMRLADAFERDDSPRERAWKRIVTPAAKFWVCKRAVELTGEVMEVFGGNGYVDDGPIARLFREAPVNSIWEGSGNVMCLDVLRAVSREPDSAAALFAELADLGAGEPRIRAALDALRAMLAAPADTLEASGRVFAQRLAIVAQACLLRRDAPAAVADAFVATRLAAPDWGRIAGGFDPHALDVAALLQRAYPA
>NZ_AP018111.1|WP_096472146.1|2327408_2328917_-|AMP-binding-protein
MNLVAALDRAARATPDKPFLVSESATITYAAARERSHRAAAVLSALGIAAGDRVAAMCFNTPAFVDLMFGAWRLGATFVPVNHKLQAPEVDYVLEHSRSKVLLFDVALAPVVERIVHPARRLVTEGELDGVPCFDTMCATMDGVAGIEPADGDIAQILYTSGTTGRPKGCVHSHRTVTLAAMSAALATGIGRNERTLMAMPIWHSSPLNNWFGGTLVAGGTVVLLREYHPLRFLQTVERERVTLYFGAPVSYTLPLDTIDGFAAFDLSSVRAWLYGGGPIGAAQAERLARAYRSDAFFQVYGMTETGPAGTTLYPDEQIAKAGSIGRHGGPGVDLRVVRMDGIDARPGETGEIWLKADSMMLGYLDDANATRAAFAPGGWYRTGDIARIDQDRYLFIVDRLKDMIVTGGENVYSKEVEDVLGAHPDIAEAAVVGVPHPDWGETVVAHVVMRAGTVPDADALRAFCGERLAAYKIPREFAFAQALPRTPTGKLQKFLLRVRKE
>NZ_AP018111.1|WP_096472145.1|2326157_2327297_+|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein
MQHTMKKVAGATFVAVMSLAGTAHADDVKIGYAGPMTGAQAHYGKDMQNGIVLALEDFNATNPKIGGKPVKFVLNTQDDQADPRTGTTVAQKLVDDGIKGMLGHFNSGTTIPASRIYANAGIPEIAMATAPEYTQQGYKTTFRMMTSDTQQGSVAGTFASKDLGMKKIAIVDDRTAYGQGLADQFEKAAKAGGATIVDREFTNDKAVDFKAILTKLKSAKPDLVYYGGADSQAAPMVKQMKALGIAAPLMSGEMVKTPTFLKIAGNASEGTIASLAGLPLEEMPGGKAYADKYKKRFGEEVQTYSPYAYDGAMAMLNAMKKADSTDPAKYLPVLAKSDMAGVTSTHVAYDAKGDLKNGGITMYKVEKGEWKPLKSIGGK
>NZ_AP018111.1|WP_096472144.1|2322140_2326073_+|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase
MASTTLGVKVDDLLRSRLKDAAARLERTPHWLIKQAIFAYLERIEHGQLPPELSGHSGVTELADGQAADGDDDNSPHPFLEFAQNVQPQSVLRAAITAAYRRPEPECVPFLLGQARLPANLQADAQALATKLVEALREKSSGGGVEGLIHEFSLSSQEGVALMCLAEALLRIPDRATRDALIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGRGGEPLIRKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDAQRYYASYEQAIHAIGKAAGGRGIYEGPGISIKLSALHARYSRSQQDRTMSELLPRVRSLALLARRYDIGLNIDAEEADRLELSLDLLEALCFDQDLAGWNGIGFVVQGYQKRCPFVIDYLIDLARRSRHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQFATHNAYTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSFVNRIADKSVSVKELVADPVDEAMKVVPLGAPHAKIPLPRNLYGDERPNSMGLDLSNEHRLASLSSALLASAHFPWRAAPMLADDALADAPARDVRNPADQRDAVGTVSEATAEHVSAALAHAVAAAPIWQATPVDARADCLVRAADLLEAQMHTLMGLIVREAGKSLPNAIAEIREAVDFLRYYAAQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPLIAAQAVRLLREAGVPAGAVQLLPGDGETVGAALVADPRTRAVMFTGSTEVARLINKTLAARLDPDGKPIPLIAETGGQNAMIVDSSALAEQVVADVMQSSFDSAGQRCSALRVLCLQDDVADRTLTMLKGAMHELALGNPDRLSTDVGPVIDGEAKQTIDTHVAAMKDKGHAVTQLPAPDACAHGTFVPPTLIEIGSIDELKREVFGPVLHVVRYRRSQLDKLLEQIRATGYGLTLGIHTRIDETIAHVISNAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPSGLPRSLAQTLMADGAVEGDARGNPAAALTTLRDWLIEQREPVLAARCDGYLAQVPAGATAVLTGPTGERNTYTLGPRGTVLCVAATPGGARAQFAAVLATGNRALFAGAAGEALVAALPASLKAHAAVRKQADVAFDAVLFEGDSDELQTLVKDVAQRPGPIVSVQGVSVGAFENGDAEDYALERLLTERSVSVNTAAAGGNANLMTIG
>NZ_AP018111.1|WP_096472153.1|2338829_2339204_+|zinc-ribbon-domain-containing-protein
MNFLKRILGGHGGGHGSGHGNSGGSGGSSGHHGGQRRDGHGGHDARGRDRHGWGWQAPADGNGGQGGNVPLSQLACAGCGALNAADARFCAQCGASQRGKACSRCHAALAADARFCPGCGTQAA
>NZ_AP018111.1|WP_096472154.1|2339284_2340163_-|AraC-family-transcriptional-regulator
MTVETKTDKPAWIRYAASVARVHEYIRAHLDGPLDLNRLAEVACLSPYHWQRVYRALYGESIVLTVRRMRIVRASEDLVCTARPIDEIARRAGYGSTHAFARAFRDTYGVLPAQHRRTGVHRPIYPLQRGEEDMFKHEVEIRRLPELRGYAVAHTGAYMKVDDAFARIGAWVGQHGLIGPGAKMIGIFYDDPDTTPEAQLRAKACFMPADGAPDVEPVPPVERATVAGGEYAVLLHTGPYADLKTAYQWLYGDWLRHSGREAADAPPFELYLNTPMDAAPADLRTEIYLPLR
>NZ_AP018111.1|WP_096472155.1|2340439_2341903_+|mechanosensitive-ion-channel
MDASSFITSLQTTLGGYLPKIAGAIGILVIGWLIAVVARAGALRLLSALKVDQRINESTGQGAYVERIIAGGLFWLVLLVTAVGIFNVLNLYAVSNPFSLLVTHIVNYLPNLIGGAALTLIAWLIASLLRSLANRALRASKIDDKLSEGAGMQPMSGYLGDVLFWLVILMFLPAILASFALSGLLSPVQGMVDKLLAIVPNLFAAAVIGFVGWVVARVLRGLVTNLLVAAGADRLTQRLDSPTPVRVSSLVGTIVYVFVFVPTLISALDALKIDAISGPATNMLNQFLGAVPDIVAAIVIVLVTFYFARFVASLAQKLLEAAGADGLPAVLGVERVFSGILQPSVLVARLIVFFAMLFASVEAANRLGFSQVRDVVTLFIEFGGHVLMGGVILVIGVWLAGLARRVIEQADREHSVLFARIAQFAILGLVFAMGLRAMGIANEIVQLAFGLVLGAIAVAVALSFGLGGREAAGKLLDRWFNQRSGGQ
>NZ_AP018111.1|WP_096472156.1|2342089_2343502_+|ethanolamine-permease
MKAESNGRPAAGAKSSGQPALQQTLGTWQLWGIAVGLVISGEYFGWSYGWASAGTLGFVVTALFVAAMYTTFIFSFTELTTSIPHAGGPFAYARRAFGPTGGYIAGAATLVEFVFAPPAIALAIGAYLHVQFPGLEPKHAAMGAYLVFMALNIVGVQIAATFELVITLLAIFELLVFMGVVSPGFAWSNFMKGGWSGADHFSVGAFHGMFAAIPFAIWFFLAIEGVAMAAEEAKNPKRSIPIAYVAGILTLVALAIGVMVFAGGAGDWTKLANINDPLPQAMKYIVGANSGWMHMLVWLGLFGLVASFHGIILGYSRQIFALAREGYLPEWLGKVHPRFKTPHRAILAGGVVGIAAIYSDELIQFGGQTLTANIVTMSVFGAIVMYIVSMASLFKLRRSQPNMARPFRAPLYPIFPAFAILAALVCLGTMVYFNGLVALVFLGFLAVGYAYFLATRSQRESAPGDALLEE
>NZ_AP018111.1|WP_096472157.1|2343593_2344991_+|ethanolamine-ammonia-lyase-subunit-EutB
MSYTETIGPRTYRFADLKTLLAKASPLRSGDQLAGVAAASEEERVAAKIALAGVPLKAFLNEAVIPYEDDEVTRLIVDDHDAAAFAEISHLTVGDFRNWLLSPAADGAALERIAPGLTPEMVAAVSKLMRNQDLIAAARKRRVVTRFRNTVGLAGRMSVRLQPNHPTDDVKGIAASMLDGLMYGCGDAMIGINPATDSLAAIVKLLAMIDGFRERYGVPTQSCVLTHVTNTIAAIEKGAPVDLVFQSIAGTEKANASFGISLALLGEAREAALSLKRGTVGNNLMYFETGQGSALSANAHHGVDQQTCEVRAYAVARKFEPFLVNTVVGFIGPEYLYDGKQIIRAGLEDHFCGKLLGVPMGCDICYTNHAEADQDDMDTLLTLLGAAGINFIMGIPGADDVMLNYQSTSFHDQLYVREVLGLRRAPEFEEWLETMEIADSHGALRAASARVPLLAGANDWMGLSA
>NZ_AP018111.1|WP_096472158.1|2344987_2345782_+|ethanolamine-ammonia-lyase-subunit-EutC
MSDAVEKNPWGQLKSFTNARIALGRAGNSLPTAPLLAFNLSHAQARDAVHQPLDADALRREIEAAGLLPTLGVQSAAPDRDHYLRRPDLGRKLSDDSRGLLAGYGAALDDAPDVVFVVGDGLSAFAAAKQALPLLQAVRPRLDADGWRIGPVVVAKQARVALGDEIGELLRAKVVAMLIGERPGLSSPDSLGVYLTWAPKVGCHDALRNCISNVRPEGLPHAAAAHKLHYLMTHARRLQLTGVGLKDDSDALLPPAETERIGAA
>NZ_AP018111.1|WP_096472159.1|2345812_2346697_-|LysR-family-transcriptional-regulator
MENLTGIVAFVRTADALSFVAAGRALGISASAVGKTIAKLEQSLGVRLFNRTTRRVTLTEEGRHFYERCQRILEDFRDAEATVTASAQRPRGKLRVSLPVIGYRFLLPVLPEFRQRYPDVELDLDFNDRMVDVVEGGFDAVIRSGPLSDSSLMSRRLGPFAFVLCATPAYLAQAGTPRTPRDLEAHDCVRYCFPTTGKLQDWALAADDGTPLKLRTAMTCNNMEALRGTVLAGLGIGYMPDFLARDALEHGALVTVLDDYRIAPGQFSIVWPSSRQLSPKLRVFVDFLCERLFR
>NZ_AP018111.1|WP_096472160.1|2346852_2348463_+|MFS-transporter
MDHAFSAVSAVSARRRAWVLAAVCMAAVALPLSFSGGAVATPAIGRDLHGGTVAMNWITNAFMLAFGSCLMAAGALADQFGRKRLFAIGVGGFTLMSVALAFAPSMLAVDLLRGAQGLAAAAALAGGTAALAQEFDGAARTRAFSLLGTTFGIGLAFGPVLAGGLIGHYGWRAIFVTSAVAGVLSLGFGLPRMRESRDPHATGLDWPGTAAFTAALTLFTFGVIEAPARGWTSTLVIVLLAGAALGALAFVMIETRVARPMLDLSLFRIARFVGVQVLPVSTCCCYIVLLVVLPLRFIGIDGFSEIDAGWLMLAISAPMLVVPFVAATLTRWLSAGMISALGLVVAAGGLVWLGVALRGGAGPAAIAPMLAIGVGAGMPWGLMDGLSVSVVPKERAGMATGIFSTTRVAGEGIALAIVGAVLAALAQTGLRQAAGAAGTPDATLRAAARLATGDLAGAAAALPGVGHAALLASYTHAFDRLLTGLAVVTVLCAVVVFVFLGGRPAVEAGDDADGHAHADAPARSRIEPACAETHGR
>NZ_AP018111.1|WP_096472161.1|2348648_2349125_-|pyridoxamine-5'-phosphate-oxidase-family-protein
MRIAHPHAAAFAPTDTMSDSAPLTDDAVAFIREQAFLIVATADAAGNSDCSYRGRQPRADGSFEPLVDIPDRRTLVLPDFAGNNLFNTIGNLLVNPAIALLFVDFVRQTTWLVQGRATIDEDPGSRAHLWPDARRHVVIEVERAQVRADAALPPLVLA
>NZ_AP018111.1|WP_096472162.1|2349407_2350934_+|aldehyde-dehydrogenase
MNPFDLKQLGLDVEYPYRQQYDNYIGGKWVAPVKGEYFENVSPINGQPFCRIPRSGADDIELALDAAHAARRKWGKTSVAERANLLLAAADRMEKNLKLLAVAETIDNGKPLRETMAADLPLAIDHFRYFAGCIRAQEGGISEIDDNTVAYHFHEPLGVVGQIIPWNFPLLMAAWKLAPALAAGCCVVMKPAEQTPASVLVLMELIGDLFPAGTINIVNGFGKEAGEALATSKRIAKIAFTGSTPVGKHILRAAADSLIPSTVELGGKSPNIFFADVLDQDDAFLDKALEGLAMFALNQGEVCTCPSRILIQESIYERFIEKAVARVERIKSGHPLDLQTMIGAQASQQQLDKILSYIDIGRGEGAQCLTGGERTAPAAGLDTGYYVKPTMLLGNNKMRVFQEEIFGPVASVMTFKDEQEAIELANDTFYGLGAGVWTRNGTRAYRMGREVEAGRVWTNCYHLYPAHAAFGGYKQSGIGRETHKMALSNYQQTKCLLVSYQAEALGFF

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Crispr_ID: NZ_AP018111_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP018111_6

2348494-2348602

Orphan

Consensus_repeat	Method
GATGGCAGCCGGAGCGCCCGTGCAGTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP018111_6

>merge|NZ_AP018111|6|2348494-2348602|CRISPRCasFinder
GATGGCAGCCGGAGCGCCCGTGCAGTGATGCATCACCGCATCAGCGCGTTGAGCGTCGCGTCATCGCGCGTGGGGCTTTGGCGATGGCAGCCGGAGCGCCCGTGCAGTG

>NZ_AP018111|6|5|2348494-2348602|CRISPRCasFinder
GATGGCAGCCGGAGCGCCCGTGCAGTG	ATGCATCACCGCATCAGCGCGTTGAGCGTCGCGTCATCGCGCGTGGGGCTTTGGC
GATGGCAGCCGGAGCGCCCGTGCAGTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP018111.1\|WP_096472158.1\|2344987_2345782_+\|ethanolamine-ammonia-lyase-subunit-EutC	unknown	unknown	gnl\|CDD\|235482
NZ_AP018111.1\|WP_096472159.1\|2345812_2346697_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176165
NZ_AP018111.1\|WP_096472168.1\|2356658_2356943_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|368240
NZ_AP018111.1\|WP_096472160.1\|2346852_2348463_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_AP018111.1\|WP_096472157.1\|2343593_2344991_+\|ethanolamine-ammonia-lyase-subunit-EutB	unknown	unknown	gnl\|CDD\|237897
NZ_AP018111.1\|WP_096472166.1\|2354191_2355895_-\|thiamine-pyrophosphate-binding-protein	unknown	unknown	gnl\|CDD\|181285
NZ_AP018111.1\|WP_096472153.1\|2338829_2339204_+\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|372305
NZ_AP018111.1\|WP_096472154.1\|2339284_2340163_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|336409
NZ_AP018111.1\|WP_096472164.1\|2352023_2353058_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|182258
NZ_AP018111.1\|WP_096472169.1\|2357058_2358447_-\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|273233
NZ_AP018111.1\|WP_096472152.1\|2336254_2338819_+\|heavy-metal-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319845
NZ_AP018111.1\|WP_096472167.1\|2356200_2356662_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP018111.1\|WP_096472165.1\|2353100_2354195_-\|ADP-heptose--LPS-heptosyltransferase	unknown	unknown	gnl\|CDD\|340821
NZ_AP018111.1\|WP_096472162.1\|2349407_2350934_+\|aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143434
NZ_AP018111.1\|WP_011546785.1\|2335741_2336173_-\|Cd(II)/Pb(II)-responsive-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133411
NZ_AP018111.1\|WP_096473114.1\|2358477_2359614_-\|alginate-lyase-family-protein	unknown	unknown	gnl\|CDD\|377511
NZ_AP018111.1\|WP_096472163.1\|2351268_2351811_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274926
NZ_AP018111.1\|WP_096472156.1\|2342089_2343502_+\|ethanolamine-permease	unknown	unknown	gnl\|CDD\|129986
NZ_AP018111.1\|WP_096472161.1\|2348648_2349125_-\|pyridoxamine-5'-phosphate-oxidase-family-protein	unknown	unknown	gnl\|CDD\|274926
NZ_AP018111.1\|WP_096472155.1\|2340439_2341903_+\|mechanosensitive-ion-channel	unknown	unknown	gnl\|CDD\|377524

Protein	Function_ID	Function_description	E-value
NZ_AP018111.1\|WP_096472158.1\|2344987_2345782_+\|ethanolamine-ammonia-lyase-subunit-EutC	gnl\|CDD\|235482	PRK05465, PRK05465, ethanolamine ammonia-lyase subunit EutC.	1.36022e-138
NZ_AP018111.1\|WP_096472159.1\|2345812_2346697_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176165	cd08476, PBP2_CrgA_like_7, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold. This CD represents the substrate binding domain of an uncharacterized LysR-type transcriptional regulator (LTTR) CrgA-like 7. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	6.24915e-117
NZ_AP018111.1\|WP_096472168.1\|2356658_2356943_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|368240	pfam05016, ParE_toxin, ParE toxin of type II toxin-antitoxin system, parDE. ParE is the toxin family of a type II toxin-antitoxin family. It is toxic towards DNA gyrase, but is neutralized by the antitoxin ParD. The family also encompasses RelE/ParE described in.	8.16743e-11
NZ_AP018111.1\|WP_096472160.1\|2346852_2348463_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	4.35849e-34
NZ_AP018111.1\|WP_096472157.1\|2343593_2344991_+\|ethanolamine-ammonia-lyase-subunit-EutB	gnl\|CDD\|237897	PRK15067, PRK15067, ethanolamine ammonia-lyase subunit EutB.	0
NZ_AP018111.1\|WP_096472166.1\|2354191_2355895_-\|thiamine-pyrophosphate-binding-protein	gnl\|CDD\|181285	PRK08199, PRK08199, thiamine pyrophosphate protein; Validated.	0
NZ_AP018111.1\|WP_096472153.1\|2338829_2339204_+\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|372305	pfam12773, DZR, Double zinc ribbon. This family consists of a pair of zinc ribbon domains.	1.27198e-10
NZ_AP018111.1\|WP_096472154.1\|2339284_2340163_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|336409	pfam06445, GyrI-like, GyrI-like small molecule binding domain. This family contains the small molecule binding domain of a number of different bacterial transcription activators. This family also contains DNA gyrase inhibitors. The GyrI superfamily contains a diad of the SHS2 module, adapted for small-molecule binding. The GyrI superfamily includes a family of secreted forms that is found only in animals and the bacterial pathogen Leptospira.	2.73171e-37
NZ_AP018111.1\|WP_096472164.1\|2352023_2353058_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|182258	PRK10130, PRK10130, HTH-type transcriptional regulator EutR.	8.00986e-73
NZ_AP018111.1\|WP_096472169.1\|2357058_2358447_-\|L-serine-ammonia-lyase	gnl\|CDD\|273233	TIGR00720, hypothetical_protein_NEICINOT_00681, L-serine dehydratase, iron-sulfur-dependent, single chain form. This enzyme is also called serine deaminase and L-serine dehydratase 1. L-serine ammonia-lyase converts serine into pyruvate in the gluconeogenesis pathway from serine. This enzyme is comprised of a single chain in Escherichia coli, Mycobacterium tuberculosis, and several other species, but has separate alpha and beta chains in Bacillus subtilis and related species. The beta and alpha chains are homologous to the N-terminal and C-terminal regions, respectively, but are rather deeply branched in a UPGMA tree. This enzyme requires iron and dithiothreitol for activation in vitro, and is a predicted 4Fe-4S protein. Escherichia coli Pseudomonas aeruginosa have two copies of this protein. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	0
NZ_AP018111.1\|WP_096472152.1\|2336254_2338819_+\|heavy-metal-translocating-P-type-ATPase	gnl\|CDD\|319845	cd07545, P-type_ATPase_Cd-like, P-type heavy metal-transporting ATPase, similar to Staphylococcus aureus plasmid pI258 CadA, a cadmium-efflux ATPase. CadA from gram-positive Staphylococcus aureus plasmid pI258 is required for full Cd(2+) and Zn(2+) resistance. This subfamily also includes CadA, from the gram-negative bacilli, Stenotrophomonas maltophilia D457R, which is a cadmium efflux pump acquired as part of a cluster of antibiotic and heavy metal resistance genes from gram-positive bacteria. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_AP018111.1\|WP_096472165.1\|2353100_2354195_-\|ADP-heptose--LPS-heptosyltransferase	gnl\|CDD\|340821	cd03789, GT9_LPS_heptosyltransferase, lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	3.33032e-08
NZ_AP018111.1\|WP_096472162.1\|2349407_2350934_+\|aldehyde-dehydrogenase	gnl\|CDD\|143434	cd07116, ALDH_ACDHII-AcoD, Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like. Included in this CD is the NAD+-dependent, acetaldehyde dehydrogenase II (AcDHII, AcoD, EC=1.2.1.3) from Ralstonia (Alcaligenes) eutrophus H16 involved in the catabolism of acetoin and ethanol, and similar proteins, such as, the dimeric dihydrolipoamide dehydrogenase of the acetoin dehydrogenase enzyme system of Klebsiella pneumonia. Also included are sequences similar to the NAD+-dependent chloroacetaldehyde dehydrogenases (AldA and AldB) of Xanthobacter autotrophicus GJ10 which are involved in the degradation of 1,2-dichloroethane. These proteins apparently require RpoN factors for expression.	0
NZ_AP018111.1\|WP_011546785.1\|2335741_2336173_-\|Cd(II)/Pb(II)-responsive-transcriptional-regulator	gnl\|CDD\|133411	cd04784, HTH_CadR-PbrR, Helix-Turn-Helix DNA binding domain of the CadR and PbrR transcription regulators. Helix-turn-helix (HTH) CadR and PbrR transcription regulators including Pseudomonas aeruginosa CadR and Ralstonia metallidurans PbrR that regulate expression of the cadmium and lead resistance operons, respectively. These proteins are comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the C-terminal domains have three conserved cysteines which form a putative metal binding site. Some members in this group have a histidine-rich C-terminal extension. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	7.7259e-63
NZ_AP018111.1\|WP_096473114.1\|2358477_2359614_-\|alginate-lyase-family-protein	gnl\|CDD\|377511	pfam05426, Alginate_lyase, Alginate lyase. This family contains several bacterial alginate lyase proteins. Alginate is a family of 1-4-linked copolymers of beta -D-mannuronic acid (M) and alpha -L-guluronic acid (G). It is produced by brown algae and by some bacteria belonging to the genera Azotobacter and Pseudomonas. Alginate lyases catalyze the depolymerization of alginates by beta -elimination, generating a molecule containing 4-deoxy-L-erythro-hex-4-enepyranosyluronate at the nonreducing end. This family adopts an all alpha fold.	9.16539e-41
NZ_AP018111.1\|WP_096472163.1\|2351268_2351811_+\|hypothetical-protein	gnl\|CDD\|274926	TIGR04025, hypothetical_protein, PPOX class probable FMN-dependent enzyme, DR_2398 family. Members of the PPOX family (see pfam01243) may contain either FMN or F420 as cofactor. This subfamily consists of proteins mostly from species that lack the capability to synthesize F420, and therefore most likely all bind FMN.	1.08461e-06
NZ_AP018111.1\|WP_096472156.1\|2342089_2343502_+\|ethanolamine-permease	gnl\|CDD\|129986	TIGR00908, putative_ethanolamine_permease, ethanolamine permease. The three genes used as the seed for this model (from Burkholderia pseudomallei, Pseudomonas aeruginosa and Clostridium acetobutylicum are all adjacent to genes for the catabolism of ethanolamine. Most if not all of the hits to this model have a similar arrangement of genes. This group is a member of the Amino Acid-Polyamine-Organocation (APC) Superfamily. [Transport and binding proteins, Amino acids, peptides and amines].	0
NZ_AP018111.1\|WP_096472161.1\|2348648_2349125_-\|pyridoxamine-5'-phosphate-oxidase-family-protein	gnl\|CDD\|274926	TIGR04025, hypothetical_protein, PPOX class probable FMN-dependent enzyme, DR_2398 family. Members of the PPOX family (see pfam01243) may contain either FMN or F420 as cofactor. This subfamily consists of proteins mostly from species that lack the capability to synthesize F420, and therefore most likely all bind FMN.	2.01806e-17
NZ_AP018111.1\|WP_096472155.1\|2340439_2341903_+\|mechanosensitive-ion-channel	gnl\|CDD\|377524	pfam05552, TM_helix, Conserved TM helix. This alignment represents a conserved transmembrane helix as well as some flanking sequence. It is often found in association with pfam00924.	9.49026e-10

>NZ_AP018111.1|WP_096472160.1|2346852_2348463_+|MFS-transporter
MDHAFSAVSAVSARRRAWVLAAVCMAAVALPLSFSGGAVATPAIGRDLHGGTVAMNWITNAFMLAFGSCLMAAGALADQFGRKRLFAIGVGGFTLMSVALAFAPSMLAVDLLRGAQGLAAAAALAGGTAALAQEFDGAARTRAFSLLGTTFGIGLAFGPVLAGGLIGHYGWRAIFVTSAVAGVLSLGFGLPRMRESRDPHATGLDWPGTAAFTAALTLFTFGVIEAPARGWTSTLVIVLLAGAALGALAFVMIETRVARPMLDLSLFRIARFVGVQVLPVSTCCCYIVLLVVLPLRFIGIDGFSEIDAGWLMLAISAPMLVVPFVAATLTRWLSAGMISALGLVVAAGGLVWLGVALRGGAGPAAIAPMLAIGVGAGMPWGLMDGLSVSVVPKERAGMATGIFSTTRVAGEGIALAIVGAVLAALAQTGLRQAAGAAGTPDATLRAAARLATGDLAGAAAALPGVGHAALLASYTHAFDRLLTGLAVVTVLCAVVVFVFLGGRPAVEAGDDADGHAHADAPARSRIEPACAETHGR
>NZ_AP018111.1|WP_096472159.1|2345812_2346697_-|LysR-family-transcriptional-regulator
MENLTGIVAFVRTADALSFVAAGRALGISASAVGKTIAKLEQSLGVRLFNRTTRRVTLTEEGRHFYERCQRILEDFRDAEATVTASAQRPRGKLRVSLPVIGYRFLLPVLPEFRQRYPDVELDLDFNDRMVDVVEGGFDAVIRSGPLSDSSLMSRRLGPFAFVLCATPAYLAQAGTPRTPRDLEAHDCVRYCFPTTGKLQDWALAADDGTPLKLRTAMTCNNMEALRGTVLAGLGIGYMPDFLARDALEHGALVTVLDDYRIAPGQFSIVWPSSRQLSPKLRVFVDFLCERLFR
>NZ_AP018111.1|WP_096472158.1|2344987_2345782_+|ethanolamine-ammonia-lyase-subunit-EutC
MSDAVEKNPWGQLKSFTNARIALGRAGNSLPTAPLLAFNLSHAQARDAVHQPLDADALRREIEAAGLLPTLGVQSAAPDRDHYLRRPDLGRKLSDDSRGLLAGYGAALDDAPDVVFVVGDGLSAFAAAKQALPLLQAVRPRLDADGWRIGPVVVAKQARVALGDEIGELLRAKVVAMLIGERPGLSSPDSLGVYLTWAPKVGCHDALRNCISNVRPEGLPHAAAAHKLHYLMTHARRLQLTGVGLKDDSDALLPPAETERIGAA
>NZ_AP018111.1|WP_096472157.1|2343593_2344991_+|ethanolamine-ammonia-lyase-subunit-EutB
MSYTETIGPRTYRFADLKTLLAKASPLRSGDQLAGVAAASEEERVAAKIALAGVPLKAFLNEAVIPYEDDEVTRLIVDDHDAAAFAEISHLTVGDFRNWLLSPAADGAALERIAPGLTPEMVAAVSKLMRNQDLIAAARKRRVVTRFRNTVGLAGRMSVRLQPNHPTDDVKGIAASMLDGLMYGCGDAMIGINPATDSLAAIVKLLAMIDGFRERYGVPTQSCVLTHVTNTIAAIEKGAPVDLVFQSIAGTEKANASFGISLALLGEAREAALSLKRGTVGNNLMYFETGQGSALSANAHHGVDQQTCEVRAYAVARKFEPFLVNTVVGFIGPEYLYDGKQIIRAGLEDHFCGKLLGVPMGCDICYTNHAEADQDDMDTLLTLLGAAGINFIMGIPGADDVMLNYQSTSFHDQLYVREVLGLRRAPEFEEWLETMEIADSHGALRAASARVPLLAGANDWMGLSA
>NZ_AP018111.1|WP_096472156.1|2342089_2343502_+|ethanolamine-permease
MKAESNGRPAAGAKSSGQPALQQTLGTWQLWGIAVGLVISGEYFGWSYGWASAGTLGFVVTALFVAAMYTTFIFSFTELTTSIPHAGGPFAYARRAFGPTGGYIAGAATLVEFVFAPPAIALAIGAYLHVQFPGLEPKHAAMGAYLVFMALNIVGVQIAATFELVITLLAIFELLVFMGVVSPGFAWSNFMKGGWSGADHFSVGAFHGMFAAIPFAIWFFLAIEGVAMAAEEAKNPKRSIPIAYVAGILTLVALAIGVMVFAGGAGDWTKLANINDPLPQAMKYIVGANSGWMHMLVWLGLFGLVASFHGIILGYSRQIFALAREGYLPEWLGKVHPRFKTPHRAILAGGVVGIAAIYSDELIQFGGQTLTANIVTMSVFGAIVMYIVSMASLFKLRRSQPNMARPFRAPLYPIFPAFAILAALVCLGTMVYFNGLVALVFLGFLAVGYAYFLATRSQRESAPGDALLEE
>NZ_AP018111.1|WP_096472155.1|2340439_2341903_+|mechanosensitive-ion-channel
MDASSFITSLQTTLGGYLPKIAGAIGILVIGWLIAVVARAGALRLLSALKVDQRINESTGQGAYVERIIAGGLFWLVLLVTAVGIFNVLNLYAVSNPFSLLVTHIVNYLPNLIGGAALTLIAWLIASLLRSLANRALRASKIDDKLSEGAGMQPMSGYLGDVLFWLVILMFLPAILASFALSGLLSPVQGMVDKLLAIVPNLFAAAVIGFVGWVVARVLRGLVTNLLVAAGADRLTQRLDSPTPVRVSSLVGTIVYVFVFVPTLISALDALKIDAISGPATNMLNQFLGAVPDIVAAIVIVLVTFYFARFVASLAQKLLEAAGADGLPAVLGVERVFSGILQPSVLVARLIVFFAMLFASVEAANRLGFSQVRDVVTLFIEFGGHVLMGGVILVIGVWLAGLARRVIEQADREHSVLFARIAQFAILGLVFAMGLRAMGIANEIVQLAFGLVLGAIAVAVALSFGLGGREAAGKLLDRWFNQRSGGQ
>NZ_AP018111.1|WP_096472154.1|2339284_2340163_-|AraC-family-transcriptional-regulator
MTVETKTDKPAWIRYAASVARVHEYIRAHLDGPLDLNRLAEVACLSPYHWQRVYRALYGESIVLTVRRMRIVRASEDLVCTARPIDEIARRAGYGSTHAFARAFRDTYGVLPAQHRRTGVHRPIYPLQRGEEDMFKHEVEIRRLPELRGYAVAHTGAYMKVDDAFARIGAWVGQHGLIGPGAKMIGIFYDDPDTTPEAQLRAKACFMPADGAPDVEPVPPVERATVAGGEYAVLLHTGPYADLKTAYQWLYGDWLRHSGREAADAPPFELYLNTPMDAAPADLRTEIYLPLR
>NZ_AP018111.1|WP_096472153.1|2338829_2339204_+|zinc-ribbon-domain-containing-protein
MNFLKRILGGHGGGHGSGHGNSGGSGGSSGHHGGQRRDGHGGHDARGRDRHGWGWQAPADGNGGQGGNVPLSQLACAGCGALNAADARFCAQCGASQRGKACSRCHAALAADARFCPGCGTQAA
>NZ_AP018111.1|WP_096472152.1|2336254_2338819_+|heavy-metal-translocating-P-type-ATPase
MTDAQRTHDPRHRHAGGADTCCADARDTHAATVADAAPAAGEHAHGDAASRGHDHDHGHGGGEGHDHDHAHGDAHAHGAACSHDHAAHDHAGHDHDHDHDHDHDHDHDHDHDHDHDHAAGDCCAPAALTLAPLPVAQATASGHVRSAFRIMQMDCPTEETLIRKKLGGMSEVSALEFNLMQRMLTVEHVPGAQPAIESAIRTLGMTPEAASAGAPAARVADAPAKPWWPLALAGVAAIASEGATWAGLPVWLSAALALVAVLACGLTTYKKGWIAIRNGNLNINALMSIAVTGAMAIGQWPEAAMVMVLFTIAELIEAKSLDRARNAIQGLMQLAPDTATVQEADGSWRTIEAAQVALGAVVRVKPGERIGLDGEVVAGRSTVNQAPITGESLPVEKTSGDAVYAGTINEAGSFEYRVTAVAANSTLARIIHAVEEAQGAKAPTQRFVDQFARVYTPIVFAVALLVAVVPPLVMGGAWHDWIYRALVLLVIACPCALVISTPVTIVSGLAAAARRGILVKGGVYLEEGRKLAWLALDKTGTITHGKPVQTDFDAHATDVDAERIRHLGASLAARSDHPVSQAIAAAARDAGTAAFADVQDFEALVGRGVRGTIDGARYWLGNHRLVEELERCSPALEAKLDALERQGKSVVVLVDDARVLGIFAVADTIKGTSRDAIAELHALGIRTAMLTGDNPHTAQAIAQQAGIDDARGNQLPEDKLAAVEELSAGGAGAVGMVGDGINDAPALARADIGFAMGAMGTDTAIETADVALMDDDLRKIPAFVRLSRATHRVLVQNIGFALGVKIVFLGLTVAGLGTMWMAVFADAGASLIVVANGLRLLSSSGAFGGAQATR
>NZ_AP018111.1|WP_011546785.1|2335741_2336173_-|Cd(II)/Pb(II)-responsive-transcriptional-regulator
MKIGELAKAARCTPETIRFYEKEGLMPDAERTDSNYRNYTDVHVERLRFIRNCRALDMAHDEIRALLQLTDTPADRCDSINSLLDDHIGHVDARLAELTHLRDQLTELRRQCVGEHSVEDCGIVHGLATMETVAPAAKRSHLG
>NZ_AP018111.1|WP_096472161.1|2348648_2349125_-|pyridoxamine-5'-phosphate-oxidase-family-protein
MRIAHPHAAAFAPTDTMSDSAPLTDDAVAFIREQAFLIVATADAAGNSDCSYRGRQPRADGSFEPLVDIPDRRTLVLPDFAGNNLFNTIGNLLVNPAIALLFVDFVRQTTWLVQGRATIDEDPGSRAHLWPDARRHVVIEVERAQVRADAALPPLVLA
>NZ_AP018111.1|WP_096472162.1|2349407_2350934_+|aldehyde-dehydrogenase
MNPFDLKQLGLDVEYPYRQQYDNYIGGKWVAPVKGEYFENVSPINGQPFCRIPRSGADDIELALDAAHAARRKWGKTSVAERANLLLAAADRMEKNLKLLAVAETIDNGKPLRETMAADLPLAIDHFRYFAGCIRAQEGGISEIDDNTVAYHFHEPLGVVGQIIPWNFPLLMAAWKLAPALAAGCCVVMKPAEQTPASVLVLMELIGDLFPAGTINIVNGFGKEAGEALATSKRIAKIAFTGSTPVGKHILRAAADSLIPSTVELGGKSPNIFFADVLDQDDAFLDKALEGLAMFALNQGEVCTCPSRILIQESIYERFIEKAVARVERIKSGHPLDLQTMIGAQASQQQLDKILSYIDIGRGEGAQCLTGGERTAPAAGLDTGYYVKPTMLLGNNKMRVFQEEIFGPVASVMTFKDEQEAIELANDTFYGLGAGVWTRNGTRAYRMGREVEAGRVWTNCYHLYPAHAAFGGYKQSGIGRETHKMALSNYQQTKCLLVSYQAEALGFF
>NZ_AP018111.1|WP_096472163.1|2351268_2351811_+|hypothetical-protein
MAEPPRSFPRHPVFHAGELDAQHRFGVADEAERMSDVVTTRVSIGVRQFVESQPFMFVGTACGGRAPVTCDIVQSLRDANGDLLPVVRVVDTKTLRFVLPAHGDGSRIDAAACDGSGVGLLFVDFVRGIRYRINGRATLHADLPEADAAPWPAGSAIVELAVAQAYGNCGTRVVRLKPAG
>NZ_AP018111.1|WP_096472164.1|2352023_2353058_+|helix-turn-helix-domain-containing-protein
MDQHVASIDEPTAEDTRRNAQGDDALAGQAVVSVAHDADEQARNLIGWRQTYDQLAAGRFVGTLTELPLDTMKLFRESTSHLLRQACEVRGDAYWFGIPLVCDGTARVDACRIGPGALAFRPGNVEFELLTPAQFSIYGVVVRGDVLRRYAEEVERSALDERLFTQCVMQVGDARLARLCALLGRRLDGAVAVTGPLPDAQRDDLQAEVLAALFDACAQPGDDGAGRAPSTRRWIVGQARDYVLAHRTRPVGVPELCEQLHVSRRTLQYCFQDVLGMAPATYLRTLRLNGARRDLCGRAAGSVQDVAEAWGFWHLSQFATDYRRLFGKRPSETLRDRAVMVAAG
>NZ_AP018111.1|WP_096472165.1|2353100_2354195_-|ADP-heptose--LPS-heptosyltransferase
MTVETRTAPPVVALSHDDALVLPGTLLAPDGTLVAPYDVEHGDARAVGHVPAAPALGLLHAAHRPFRLDYDGVRHVNVINGMGVTLGDSVIGLTALAALRAAHAGLRFTVYRPARMPRYVDALYALAADVVAPSRALPCPVEALPADAPCIDVGNHLYWPAFARLPMIDFFLDALGVDPAAVPAAAKRNRWLARLPLPALPAAWQRPYVLFCPSASTAVRSVPPALRAAFVERLAQRYGLPVAGFGPVAHPAYTDVSGDATDTARFIAWVKGASLLFAPDTAALHLADGFDVPTLACFTTIGPTLRVRDYPHCVPVELDVPAELRGLHRSERPDDLAAVEAAYRAIDWDALAWPAPREAATTTG
>NZ_AP018111.1|WP_096472166.1|2354191_2355895_-|thiamine-pyrophosphate-binding-protein
MSHSKDLEPRATTGARLLVDALLANHVERVFCVPGESFLAVLDALADDTARIQTVVCRHEAAAANMAEAVGKLTGRPGIAFVTRGPGATHASIGVHTAFQDSTPMILFVGQCAREHLDREAFQEIDYRRMFGQMAKWVAQIDDPRRIPEYLSHAFHVAVSGRPGPVVLALPEDVLSEACAPQPVVPAAKRVAAAPSAAQVDELRERLARAERPFAIVGGSGWTPDACANLRTFVERWQLPVACAFRYQDTIDNAHPNYAGDVGLGINPALAKRIRDADLLLVIGPRLGEATTGGYTLLDIPKTRQTLIHVHQGADELGRVYAADLPIVSGMPEIAAPLAALEPPEHPAWAGAAADAHRAYREWHAPLPMPGDVQLGDVMVQLRERLPHDAILTNGAGNYAIWLHRHFAYRHFRSQLAPTSGAMGYGIPAALAAKSLYPSRAVVALAGDGCFMMAGNELATAMQYGLNIVAIVVNNGHFGTIRMHQERNYPGRVHGTGLTNPDFAAYARAFGAHGETVERTADFAPALERALTCGLPALIEIRIPQDASTPAATLEQIREQGRRARGG
>NZ_AP018111.1|WP_096472167.1|2356200_2356662_+|hypothetical-protein
MATETIDQKTLIELVEAGAVRAVRVIGCGNGWAVSARCGASERLLSAKRGDVRVFRRFETLVGFLRDIGISRFDVDASDFDPDAAGRATRPDRAAALKAAHEAAVHDRWFREQVQQALDDPRPSIPDAEVSAEFASRRAVLRQRIAGKRGNAA
>NZ_AP018111.1|WP_096472168.1|2356658_2356943_+|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MTLSLHWHPKAHEDRAAIMDYIGRDDPLAALELDERLEERAAALPARAELYRQGRVAGTRELVVAPNYVLVYRIRPADNLVEILRVLHARRQWP
>NZ_AP018111.1|WP_096472169.1|2357058_2358447_-|L-serine-ammonia-lyase
MAVSVFDLFKIGIGPSSSHTVGPMRAALMFVQGLERDGLLDATAHVKVELYGSLGATGKGHGTDRGVMLGLLGDAPDTVDPETIDARLEEVRKSKKLALLGTHPVPFVLKENIAFYRQALPEHPNGMKLRASDANGAVLVERTYLSVGGGFVVTAGAPNTKVLSAAEQMTHPFRTGAELLALTESTGKSIAQLMWENERAWHTEEETRDGLLKIWAVMQSCVSRGCGIGNPEADGNLPGPFQVKRRAPQLYRTLTGSPERALQDPLSMIDWINLYAIAVNEENAAGGRVVTAPTNGAAGIIPAVLHYYTRFTPGANEQGVIDFLLTAAAIGILYKLNASISGAEVGCQGEVGVACSMAAGALAAVLGGTPQQVENAAEIGMEHNLGLTCDPVGGMVQIPCIERNAMASVKAVNAARMALRGDGSHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNIVEC
>NZ_AP018111.1|WP_096473114.1|2358477_2359614_-|alginate-lyase-family-protein
MVRPMFPGHGAMQSRPRARRFVPMLVASLSFAAAGLGAAGSARAAMNFCAAPALQASETTQAEPGVQALIRSVDARIGEQPKAMARVHTEGTLPHEGIYDQSAAAMKDMDLMRDAALAWRVTNAPRYLQLVDRFLSAWVATYQPSFNPIDETRFESLIVAYDMTASALPVKTRNATAAFIAKLGAGYVAQIDAQKRPLAGTWRNNWQSHRIKLIALSAFTLGDRKMMNAAQRLFVEHLADNIGPDGKTWDFEERDALHYAVYDLQPLVTAALAARRFNRNWLRERGANGATLAAALDWLVPYALGEKTHEEFVNSPVPFDAKRREAGLPGYTGQWDPKNATELFHLAARLDGRYARVAQQLSPTPPAWLAACLPLQAR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_AP018111_5	5.3\|2336543\|18\|NZ_AP018111\|CRISPRCasFinder	2336543-2336560	18	NZ_AP018111.1	2336573-2336590	0	1.0
NZ_AP018111_5	5.3\|2336543\|18\|NZ_AP018111\|CRISPRCasFinder	2336543-2336560	18	NZ_AP018111.1	2336579-2336596	0	1.0
NZ_AP018111_5	5.3\|2336543\|18\|NZ_AP018111\|CRISPRCasFinder	2336543-2336560	18	NZ_AP018111.1	2336585-2336602	0	1.0
NZ_AP018111_5	5.3\|2336543\|18\|NZ_AP018111\|CRISPRCasFinder	2336543-2336560	18	NZ_AP018112.1	2736419-2736436	1	0.944
NZ_AP018111_5	5.3\|2336543\|18\|NZ_AP018111\|CRISPRCasFinder	2336543-2336560	18	NZ_AP018112.1	2820973-2820990	1	0.944

1. spacer 5.3|2336543|18|NZ_AP018111|CRISPRCasFinder matches to position: 2336573-2336590, mismatch: 0, identity: 1.0

cacgaccacgaccacgac	CRISPR spacer
cacgaccacgaccacgac	Protospacer
******************

2. spacer 5.3|2336543|18|NZ_AP018111|CRISPRCasFinder matches to position: 2336579-2336596, mismatch: 0, identity: 1.0

cacgaccacgaccacgac	CRISPR spacer
cacgaccacgaccacgac	Protospacer
******************

3. spacer 5.3|2336543|18|NZ_AP018111|CRISPRCasFinder matches to position: 2336585-2336602, mismatch: 0, identity: 1.0

cacgaccacgaccacgac	CRISPR spacer
cacgaccacgaccacgac	Protospacer
******************

4. spacer 5.3|2336543|18|NZ_AP018111|CRISPRCasFinder matches to position: 2736419-2736436, mismatch: 1, identity: 0.944

cacgaccacgaccacgac	CRISPR spacer
cacgatcacgaccacgac	Protospacer
*****.************

5. spacer 5.3|2336543|18|NZ_AP018111|CRISPRCasFinder matches to position: 2820973-2820990, mismatch: 1, identity: 0.944

cacgaccacgaccacgac	CRISPR spacer
cacgaccatgaccacgac	Protospacer
********.*********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_AP018111_4	4.2\|2313719\|23\|NZ_AP018111\|CRT	2313719-2313741	23	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	409207-409229	3	0.87
NZ_AP018111_3	3.1\|2103286\|31\|NZ_AP018111\|CRISPRCasFinder	2103286-2103316	31	NZ_CP016283	Cryobacterium arcticum strain PAMC 27867 plasmid pP27867_1, complete sequence	95682-95712	9	0.71

1. spacer 4.2|2313719|23|NZ_AP018111|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 3, identity: 0.87

ttgccaaccgcggcatggggcgg	CRISPR spacer
gagccaatcgcggcatggggcgg	Protospacer
  *****.***************

2. spacer 3.1|2103286|31|NZ_AP018111|CRISPRCasFinder matches to NZ_CP016283 (Cryobacterium arcticum strain PAMC 27867 plasmid pP27867_1, complete sequence) position: , mismatch: 9, identity: 0.71

gtcccacaaggggatggggccgaagtaagcg	CRISPR spacer
caaacccagggggatgaggccgaagtaagga	Protospacer
    * **.*******.************ .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 8535

Burkholderia_phage(66.67%)

integrase

attL 1884:1897|attR 21976:21989

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1884:1897	attL	NA	NA	NA	NA
WP_157776309.1\|2950_3910_+	hypothetical protein	NA	NA	NA	NA
WP_157776310.1\|3962_4415_+	hypothetical protein	NA	NA	NA	NA
WP_157776311.1\|5510_6347_+	hypothetical protein	NA	NA	NA	NA
WP_096470493.1\|6418_7198_+	hypothetical protein	U3PBA2	Burkholderia_phage	5.6e-49	44.3
WP_157776312.1\|7216_7519_+	type II toxin-antitoxin system HicB family antitoxin	A0A0A8JBA5	Ralstonia_phage	2.4e-24	59.5
WP_096470495.1\|7515_8535_-\|integrase	site-specific integrase	A0A0A1I5U0	Burkholderia_phage	9.6e-49	38.1
21976:21989	attR	NA	NA	NA	NA

DBSCAN-SWA_2

29833 : 32877

Enterobacteria_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470509.1\|29833_30997_+	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	1.6e-36	30.6
WP_096470511.1\|31059_32877_-	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	1.2e-145	46.2

DBSCAN-SWA_3

42163 : 43381

Chrysochromulina_ericina_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470525.1\|42163_43381_+	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A0N9R0B2	Chrysochromulina_ericina_virus	4.1e-30	31.5

DBSCAN-SWA_4

53585 : 55850

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470544.1\|53585_55850_+	peptidase domain-containing ABC transporter	G9BWD6	Planktothrix_phage	5.9e-06	29.5

DBSCAN-SWA_5

70699 : 71413

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470556.1\|70699_71413_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.7e-34	38.5

DBSCAN-SWA_6

82218 : 85204

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470577.1\|82218_82968_+	response regulator transcription factor	W8CYM9	Bacillus_phage	8.1e-13	28.1
WP_096470579.1\|84478_85204_-	response regulator	W8CYM9	Bacillus_phage	3.4e-32	34.2

DBSCAN-SWA_7

91244 : 94040

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470589.1\|91244_94040_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	2.4e-25	24.9

DBSCAN-SWA_8

125329 : 126151

Acanthocystis_turfacea_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470635.1\|125329_126151_-	carbon-nitrogen hydrolase family protein	M1I4Z7	Acanthocystis_turfacea_Chlorella_virus	1.8e-13	28.6

DBSCAN-SWA_9

166461 : 174106

Serratia_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470691.1\|166461_166932_+	NUDIX hydrolase	A0A023W5N2	Serratia_phage	4.4e-25	48.1
WP_096470693.1\|167068_168778_-\|tRNA	glutamine--tRNA ligase/YqeY domain fusion protein	A0A222YZ70	Escherichia_phage	2.6e-184	57.3
WP_006497729.1\|169030_169240_+	ornithine acetyltransferase	NA	NA	NA	NA
WP_096470695.1\|169407_169956_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_096470697.1\|170005_171226_-	CoA transferase	NA	NA	NA	NA
WP_096470699.1\|171481_174106_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	2.9e-81	39.3

DBSCAN-SWA_10

179960 : 181417

Brazilian_cedratvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470711.1\|179960_180713_+	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	2.6e-11	27.9
WP_096470713.1\|180709_181417_+	ABC transporter ATP-binding protein	F2Y302	Organic_Lake_phycodnavirus	1.7e-07	30.8

DBSCAN-SWA_11

190009 : 191605

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470727.1\|190009_191605_+	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.6e-11	22.5

DBSCAN-SWA_12

207171 : 217772

Bacillus_phage(25.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470743.1\|207171_208056_-	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	5.3e-72	50.0
WP_096470744.1\|208143_211011_-\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	1.3e-146	38.8
WP_096470745.1\|211224_213588_+	UvrD-helicase domain-containing protein	G3MA40	Bacillus_virus	3.1e-74	32.2
WP_096470746.1\|213584_214382_+	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_096470747.1\|214457_215696_-	MFS transporter	NA	NA	NA	NA
WP_096470748.1\|216098_217772_+	MCP four helix bundle domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	1.3e-10	38.4

DBSCAN-SWA_13

225355 : 226186

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470754.1\|225355_226186_-	metallophosphoesterase family protein	A0A291ATQ8	Pandoravirus	8.4e-27	29.4

DBSCAN-SWA_14

233407 : 234508

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470761.1\|233407_234508_+	chorismate synthase	A0A291AU41	Pandoravirus	6.0e-81	44.1

DBSCAN-SWA_15

244256 : 251664

Tupanvirus(25.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470766.1\|244256_246164_+\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	8.1e-126	37.8
WP_080599380.1\|246213_246738_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	4.1e-11	29.3
WP_004191477.1\|246928_247126_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_004192938.1\|247156_247516_+	50S ribosomal protein L20	NA	NA	NA	NA
WP_172902946.1\|247665_248679_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2H4UW22	Bodo_saltans_virus	6.6e-26	38.6
WP_096470767.1\|248775_251205_+\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_046545481.1\|251277_251664_+	integration host factor subunit alpha	A0A1P8CWT5	Bacillus_phage	3.5e-12	41.1

DBSCAN-SWA_16

265179 : 266211

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470778.1\|265179_266211_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	3.1e-23	35.1

DBSCAN-SWA_17

270494 : 273431

Bodo_saltans_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470780.1\|270494_273431_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	5.2e-23	25.3

DBSCAN-SWA_18

286747 : 288178

Erysipelothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470788.1\|286747_288178_+	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	5.0e-43	28.0

DBSCAN-SWA_19

312215 : 313970

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470810.1\|312215_313970_-	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	1.4e-36	30.0

DBSCAN-SWA_20

322910 : 324464

Brazilian_cedratvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470817.1\|322910_324464_-	sugar ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	9.3e-11	27.5

DBSCAN-SWA_21

329341 : 333684

Lactococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470820.1\|329341_331822_+	ribonuclease R	Q0GXV6	Lactococcus_phage	1.2e-68	32.6
WP_034184068.1\|331970_332714_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_096470821.1\|332811_333684_+	N-acetylmuramoyl-L-alanine amidase	A0A076YN96	Rhizobium_phage	7.0e-08	28.1

DBSCAN-SWA_22

346999 : 347959

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470833.1\|346999_347959_+	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	4.7e-29	37.6

DBSCAN-SWA_23

358951 : 365313

Tupanvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470843.1\|358951_359425_+	VOC family protein	A0A2K9L1J4	Tupanvirus	5.3e-18	37.7
WP_096470844.1\|360275_360503_+	hypothetical protein	NA	NA	NA	NA
WP_096470845.1\|360655_361279_-	phospholipase D family protein	A0A1B2LRT6	Wolbachia_phage	2.4e-18	35.0
WP_096470846.1\|361604_362093_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_047900588.1\|362269_362707_+	PaaI family thioesterase	NA	NA	NA	NA
WP_096470847.1\|362896_363949_+	NADP(H)-dependent aldo-keto reductase	NA	NA	NA	NA
WP_096470848.1\|364026_365313_-	MFS transporter	Q6JIH2	Burkholderia_virus	2.3e-87	43.4

DBSCAN-SWA_24

371537 : 375129

Anomala_cuprea_entomopoxvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096473005.1\|371537_372452_-	nodulation factor ABC transporter ATP-binding protein NodI	W6JKT0	Anomala_cuprea_entomopoxvirus	1.2e-29	28.3
WP_034184109.1\|372782_373280_+	universal stress protein	NA	NA	NA	NA
WP_096470854.1\|373367_374090_-	DUF2939 domain-containing protein	NA	NA	NA	NA
WP_034184111.1\|374119_374455_-	hypothetical protein	NA	NA	NA	NA
WP_047900600.1\|374481_375129_-	transcriptional repressor LexA	F1C5A6	Cronobacter_phage	1.6e-09	43.4

DBSCAN-SWA_25

378401 : 379460

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_027787478.1\|378401_379460_+	sulfate ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.8e-29	35.1

DBSCAN-SWA_26

382752 : 396535

Staphylococcus_phage(20.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470861.1\|382752_384366_+	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.8e-08	26.6
WP_096470862.1\|384362_385382_+	ABC transporter permease	NA	NA	NA	NA
WP_047900610.1\|385417_386449_+	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	3.0e-34	31.8
WP_096470863.1\|386445_387375_+	ribokinase	NA	NA	NA	NA
WP_096470864.1\|387681_389457_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	6.9e-10	42.5
WP_047900613.1\|390002_391925_+	PrkA family serine protein kinase	NA	NA	NA	NA
WP_096470865.1\|392050_393319_+	YeaH/YhbH family protein	A0A219UQP6	Bacillus_phage	3.2e-09	37.2
WP_096470866.1\|393315_394995_+	SpoVR family protein	NA	NA	NA	NA
WP_065500107.1\|395230_396535_+	MFS transporter	Q6JIH2	Burkholderia_virus	1.8e-44	30.2

DBSCAN-SWA_27

410090 : 416850

Mycobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470871.1\|410090_411356_-	M23 family metallopeptidase	G8I8L5	Mycobacterium_phage	2.3e-15	40.4
WP_096470872.1\|411694_412342_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_096470873.1\|412491_413697_+	MexX/AxyX family multidrug efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_096470874.1\|413712_416850_+	multidrug efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	2.9e-51	21.3

DBSCAN-SWA_28

427935 : 428784

Anomala_cuprea_entomopoxvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470882.1\|427935_428784_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	5.6e-10	25.5

DBSCAN-SWA_29

432869 : 449542

Tupanvirus(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470886.1\|432869_434615_-	cyclic peptide export ABC transporter	G9BWD6	Planktothrix_phage	2.4e-15	25.8
WP_096470887.1\|434884_444538_+	non-ribosomal peptide synthetase	A0A2K9L3I8	Tupanvirus	2.0e-87	23.2
WP_096470888.1\|444547_449542_+	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	4.4e-46	22.2

DBSCAN-SWA_30

481469 : 482825

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_172902902.1\|481469_482825_-	chitinase	M1HTM3	Paramecium_bursaria_Chlorella_virus	3.4e-41	36.8

DBSCAN-SWA_31

509226 : 510306

Mycoplasma_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470933.1\|509226_510306_+	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	3.0e-16	46.2

DBSCAN-SWA_32

513889 : 514855

Only_Syngen_Nebraska_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470937.1\|513889_514855_-	D-2-hydroxyacid dehydrogenase	A0A1J0F959	Only_Syngen_Nebraska_virus	7.7e-24	28.9

DBSCAN-SWA_33

551277 : 556198

Leptospira_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096473018.1\|551277_554451_-	multidrug efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	9.3e-50	22.0
WP_096470969.1\|554563_556198_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.2e-15	31.1

DBSCAN-SWA_34

569750 : 570737

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096470977.1\|569750_570737_-	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	2.8e-45	36.5

DBSCAN-SWA_35

599488 : 601912

Enterobacteria_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471002.1\|599488_600532_-	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	1.6e-11	24.4
WP_096473022.1\|600946_601912_-	bifunctional glyoxylate/hydroxypyruvate reductase B	M1I1Q8	Acanthocystis_turfacea_Chlorella_virus	8.8e-20	28.2

DBSCAN-SWA_36

625857 : 627941

Mycoplasma_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471020.1\|625857_626784_-	ABC transporter permease subunit	Q6GZ02	Mycoplasma_phage	3.3e-08	24.3
WP_096471021.1\|626780_627941_-	polyamine ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.3e-22	31.4

DBSCAN-SWA_37

642171 : 648042

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047900804.1\|642171_642921_-	FkbM family methyltransferase	E3SJ86	Synechococcus_phage	3.6e-21	31.4
WP_096471035.1\|643165_644758_-	ABC-F family ATPase	A0A2K9L0W2	Tupanvirus	1.8e-54	27.1
WP_096471036.1\|644890_647188_-	AsmA family protein	NA	NA	NA	NA
WP_096471037.1\|647340_648042_+	ATP-binding cassette domain-containing protein	A0A1V0SE00	Indivirus	1.4e-06	24.7

DBSCAN-SWA_38

668957 : 671207

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471052.1\|668957_671207_-	ATP-dependent DNA helicase	A0A127AW80	Bacillus_phage	6.3e-77	29.1

DBSCAN-SWA_39

675053 : 679212

Paramecium_bursaria_Chlorella_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471055.1\|675053_676970_-	potassium transporter Kup	A7J6G4	Paramecium_bursaria_Chlorella_virus	3.2e-77	32.3
WP_047900830.1\|677262_677859_-	phosphoribosyltransferase	NA	NA	NA	NA
WP_096471056.1\|677865_679212_-	adenylosuccinate synthase	A0A160ER07	Powai_lake_megavirus	1.2e-70	36.8

DBSCAN-SWA_40

693376 : 707624

uncultured_Mediterranean_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011352265.1\|693376_693802_-	nucleoside-diphosphate kinase	A0A167REB2	Powai_lake_megavirus	2.5e-19	41.4
WP_006761414.1\|694051_694750_+	Bax inhibitor-1/YccA family protein	NA	NA	NA	NA
WP_096473027.1\|694813_696211_-	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	6.8e-29	25.7
WP_096471065.1\|696431_697286_+	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_096471066.1\|697324_698101_-	3'-5' exonuclease	NA	NA	NA	NA
WP_047900847.1\|698104_699193_-	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	3.9e-32	35.4
WP_096471067.1\|699204_700092_-	peptidoglycan DD-metalloendopeptidase family protein	NA	NA	NA	NA
WP_096471068.1\|700097_701030_-	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	3.8e-36	49.7
WP_096471069.1\|701026_701788_-	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	8.4e-66	52.0
WP_096471070.1\|702010_703216_-	CoA transferase	NA	NA	NA	NA
WP_034181272.1\|703264_703861_-	recombination protein RecR	NA	NA	NA	NA
WP_006482124.1\|703892_704219_-	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
WP_096471071.1\|704317_706681_-	DNA polymerase III subunit gamma/tau	A0A1L2BWV7	Bacteriophage	3.1e-42	40.9
WP_006402348.1\|707297_707624_+	thioredoxin TrxA	A0A1J0GW78	Streptomyces_phage	1.8e-17	44.1

DBSCAN-SWA_41

716866 : 717982

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471078.1\|716866_717982_-	acetoin dehydrogenase dihydrolipoyllysine-residue acetyltransferase subunit	A0A2K9L3Q7	Tupanvirus	1.8e-08	26.7

DBSCAN-SWA_42

726169 : 728767

Cronobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471086.1\|726169_728767_-	ATP-dependent chaperone ClpB	K4FB40	Cronobacter_phage	1.8e-120	36.9

DBSCAN-SWA_43

741025 : 742048

Cronobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471096.1\|741025_742048_+	glycosyltransferase	F1C5B0	Cronobacter_phage	9.7e-33	30.3

DBSCAN-SWA_44

745858 : 752300

Vibrio_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471099.1\|745858_747661_+	PhoH family protein	A0A2I7SAD7	Vibrio_phage	2.1e-75	39.0
WP_096471100.1\|747898_748987_+	C40 family peptidase	A0A1S5SEZ8	Streptococcus_phage	4.8e-14	36.4
WP_047900879.1\|749131_750142_-	inorganic phosphate transporter	NA	NA	NA	NA
WP_047900880.1\|750152_750779_-	DUF47 domain-containing protein	NA	NA	NA	NA
WP_096471101.1\|750917_752300_-	replicative DNA helicase	C7BGG1	Burkholderia_phage	1.0e-138	58.5

DBSCAN-SWA_45

756918 : 758694

Ostreococcus_tauri_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471105.1\|756918_758694_+	glyoxylate carboligase	E4WLQ6	Ostreococcus_tauri_virus	6.1e-43	27.3

DBSCAN-SWA_46

766142 : 767318

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471111.1\|766142_767318_-	AAA family ATPase	A0A077SLJ9	Escherichia_phage	6.7e-70	39.7

DBSCAN-SWA_47

771827 : 772448

Bacteriophage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471116.1\|771827_772448_-	dTMP kinase	A0A1L2BX49	Bacteriophage	1.9e-28	39.3

DBSCAN-SWA_48

775986 : 776946

Powai_lake_megavirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471120.1\|775986_776946_-	alpha/beta hydrolase	A0A167RJ59	Powai_lake_megavirus	6.1e-29	32.9

DBSCAN-SWA_49

781037 : 799486

Burkholderia_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_172902908.1\|781037_782051_-	NAD(P)-dependent alcohol dehydrogenase	A0A0K0KVL7	Prochlorococcus_phage	3.4e-06	23.2
WP_096471122.1\|782143_783070_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_096471123.1\|783166_784567_-	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	8.3e-19	32.0
WP_096471124.1\|784827_786006_-	acetyl-CoA C-acyltransferase	NA	NA	NA	NA
WP_096471125.1\|786050_786683_-	bifunctional nicotinamidase/pyrazinamidase	A0A2K9L2K0	Tupanvirus	1.8e-21	37.1
WP_096471126.1\|786727_788812_-	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_096471127.1\|789013_790657_-	fatty-acid--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	1.4e-20	24.4
WP_096471128.1\|790850_792419_+	YdiU family protein	A0A075BSJ0	Microcystis_phage	8.1e-55	31.6
WP_096471129.1\|792465_792897_+	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_096471130.1\|793055_793586_+	septation protein A	NA	NA	NA	NA
WP_048248478.1\|793587_793896_+	BolA family transcriptional regulator	NA	NA	NA	NA
WP_096471131.1\|793914_794697_+	peptidylprolyl isomerase	NA	NA	NA	NA
WP_172902948.1\|794870_795413_-	N-acetyltransferase	A9YX37	Burkholderia_phage	2.0e-05	70.0
WP_096471132.1\|795421_799486_-	phosphoribosylformylglycinamidine synthase	A9YX36	Burkholderia_phage	1.4e-220	90.6

DBSCAN-SWA_50

804508 : 805222

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047900927.1\|804508_805222_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.6e-32	40.1

DBSCAN-SWA_51

808422 : 813133

Moraxella_phage(33.33%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471138.1\|808422_810846_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	1.1e-223	53.0
WP_006489345.1\|811043_812315_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	6.0e-133	58.3
WP_010092137.1\|812479_813133_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	4.8e-54	55.4

DBSCAN-SWA_52

821694 : 822804

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471146.1\|821694_822804_+	class II histone deacetylase	A0A2K9KZC4	Tupanvirus	1.9e-42	34.0

DBSCAN-SWA_53

828368 : 829094

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004199523.1\|828368_829094_+	two-component system response regulator OmpR	W8CYM9	Bacillus_phage	8.1e-34	36.7

DBSCAN-SWA_54

852855 : 853776

Burkholderia_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471166.1\|852855_853776_-	LysR family transcriptional regulator	Q6JIH3	Burkholderia_virus	3.1e-22	30.3

DBSCAN-SWA_55

864051 : 864648

Pandoravirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471177.1\|864051_864648_-\|tRNA	tRNA adenosine(34) deaminase TadA	S4VYT2	Pandoravirus	1.0e-05	32.0

DBSCAN-SWA_56

873907 : 878525

Clostridium_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471185.1\|873907_874525_+	3'-5' exonuclease	A0A0A7RWA3	Clostridium_phage	3.4e-17	31.4
WP_096471186.1\|874728_876348_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	6.5e-15	27.3
WP_096471187.1\|876455_877058_-	hypothetical protein	NA	NA	NA	NA
WP_034188825.1\|877064_878525_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	9.7e-95	39.4

DBSCAN-SWA_57

884554 : 891889

Staphylococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047900992.1\|884554_885001_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	5.3e-28	44.1
WP_096471192.1\|885245_886181_-	SPFH/Band 7/PHB domain protein	NA	NA	NA	NA
WP_096471193.1\|886214_886649_-	NfeD family protein	NA	NA	NA	NA
WP_096471194.1\|886773_889173_-	phosphoenolpyruvate synthase	A0A1V0SGR7	Hokovirus	1.8e-167	35.7
WP_047900996.1\|889550_890366_+	kinase/pyrophosphorylase	NA	NA	NA	NA
WP_096471195.1\|890465_891248_-	RNA methyltransferase	NA	NA	NA	NA
WP_059599932.1\|891244_891889_-	ribonuclease HII	D2TEQ2	Emiliania_huxleyi_virus	7.0e-29	42.3

DBSCAN-SWA_58

901967 : 902750

Flavobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471204.1\|901967_902750_-	di-trans,poly-cis-decaprenylcistransferase	R9W0U9	Flavobacterium_phage	8.5e-21	39.1

DBSCAN-SWA_59

912010 : 914616

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471208.1\|912010_912544_-	peptide deformylase	A0A0E3FIY1	Synechococcus_phage	2.3e-09	35.0
WP_096471209.1\|912540_914616_-	NAD-dependent DNA ligase LigA	A0A0K2QQN8	Ralstonia_phage	8.2e-148	44.9

DBSCAN-SWA_60

927152 : 932722

Canarypox_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471218.1\|927152_927632_-	glutathione peroxidase	Q6VZR0	Canarypox_virus	3.5e-25	39.6
WP_096471219.1\|927768_929700_+	ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	7.6e-63	30.4
WP_021159088.1\|929850_930117_-	DUF2866 domain-containing protein	NA	NA	NA	NA
WP_096471220.1\|930263_931640_-	DNA repair protein RadA	NA	NA	NA	NA
WP_096471221.1\|931651_932722_-	alanine racemase	A0A0P0YM39	Yellowstone_lake_mimivirus	3.5e-25	29.5

DBSCAN-SWA_61

936096 : 940680

Pseudomonas_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471225.1\|936096_937110_-	uracil-DNA glycosylase	A0A2H4P750	Pseudomonas_phage	8.4e-05	30.1
WP_096471226.1\|937096_937597_-	ribosomal protein S18-alanine N-acetyltransferase	NA	NA	NA	NA
WP_096471227.1\|937593_938361_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_043189214.1\|938508_938778_+	acyl-CoA-binding protein	NA	NA	NA	NA
WP_096471228.1\|939138_940680_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	5.3e-43	29.0

DBSCAN-SWA_62

952120 : 955630

Klosneuvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471237.1\|952120_953047_+	patatin-like phospholipase family protein	A0A1V0SKV5	Klosneuvirus	9.7e-08	27.2
WP_096471238.1\|953204_953879_-	C40 family peptidase	A0A217EQL1	Bacillus_phage	5.6e-21	41.5
WP_096471239.1\|954007_955630_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.8e-20	32.3

DBSCAN-SWA_63

973537 : 977086

Moumouvirus(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471247.1\|973537_974935_-\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	1.4e-42	30.9
WP_172902909.1\|975169_975892_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_096471249.1\|975930_976506_+	peptidyl-prolyl cis-trans isomerase	A0A1V0SCU1	Indivirus	1.2e-11	38.5
WP_006478428.1\|976594_977086_+	peptidyl-prolyl cis-trans isomerase	A0A2H4UTF4	Bodo_saltans_virus	2.2e-06	29.6

DBSCAN-SWA_64

985492 : 988150

Indivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471255.1\|985492_988150_+	DNA mismatch repair protein MutS	A0A1V0SDQ0	Indivirus	3.6e-23	23.9

DBSCAN-SWA_65

1003583 : 1007483

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011352544.1\|1003583_1004867_-	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	1.1e-150	62.1
WP_096471272.1\|1004973_1005828_-	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	6.8e-48	40.5
WP_096471273.1\|1005824_1007483_-	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	4.1e-150	51.5

DBSCAN-SWA_66

1011991 : 1025015

Planktothrix_phage(14.29%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_172902911.1\|1011991_1012750_-	lipoprotein-releasing ABC transporter ATP-binding protein LolD	G9BWD6	Planktothrix_phage	5.5e-33	41.0
WP_034183566.1\|1012742_1013996_-	lipoprotein-releasing ABC transporter permease subunit	NA	NA	NA	NA
WP_172902912.1\|1014146_1015223_+	regulator	NA	NA	NA	NA
WP_096471278.1\|1015237_1016935_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	2.5e-57	30.3
WP_096471279.1\|1017087_1018191_+	peptide chain release factor 2	W8EDB3	Pseudomonas_phage	1.3e-06	35.4
WP_096471280.1\|1018275_1019802_+\|tRNA	lysine--tRNA ligase	A0A1V0SAC0	Catovirus	4.3e-85	35.5
WP_096471281.1\|1020150_1020891_+	glycine zipper 2TM domain-containing protein	NA	NA	NA	NA
WP_034183561.1\|1021013_1021223_-	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_047898490.1\|1021240_1021582_-	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_096471282.1\|1021673_1023542_-	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	1.0e-101	41.7
WP_096473039.1\|1023596_1024124_-	Fe-S protein assembly co-chaperone HscB	NA	NA	NA	NA
WP_011885413.1\|1024218_1024542_-	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	3.0e-25	52.3
WP_006481982.1\|1024607_1025015_-	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	1.8e-51	76.6

DBSCAN-SWA_67

1033824 : 1035591

Erysipelothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471290.1\|1033824_1035591_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	1.8e-34	23.8

DBSCAN-SWA_68

1043932 : 1047137

Enterococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471293.1\|1043932_1044793_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	1.2e-36	39.1
WP_096471294.1\|1045049_1047137_+	M3 family metallopeptidase	A0A1V0SD92	Indivirus	5.4e-38	21.9

DBSCAN-SWA_69

1061736 : 1065948

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471303.1\|1061736_1065948_-	ATP-dependent RNA helicase HrpA	A0A1V0SBU4	Catovirus	2.1e-49	30.5

DBSCAN-SWA_70

1089630 : 1091154

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471320.1\|1089630_1091154_-	histidine ammonia-lyase	A0A1V0S940	Catovirus	8.6e-78	38.8

DBSCAN-SWA_71

1097048 : 1098527

Bodo_saltans_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096473043.1\|1097048_1098527_-	deoxyribodipyrimidine photo-lyase	A0A2H4UV63	Bodo_saltans_virus	4.3e-50	39.9

DBSCAN-SWA_72

1105150 : 1107064

Hokovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471332.1\|1105150_1107064_+	sulfate adenylyltransferase subunit CysN	A0A1V0SGC3	Hokovirus	1.2e-31	29.3

DBSCAN-SWA_73

1115216 : 1117767

Caulobacter_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471341.1\|1115216_1115873_-	TerD family protein	K4JRX3	Caulobacter_phage	3.0e-35	42.2
WP_096471342.1\|1115965_1116982_-	DUF475 domain-containing protein	K4JUR1	Caulobacter_phage	3.9e-74	47.3
WP_096471343.1\|1117026_1117767_-	VWA domain-containing protein	I7HXI7	Enterobacteria_phage	3.2e-38	36.2

DBSCAN-SWA_74

1125676 : 1129582

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471348.1\|1125676_1127659_-	acetate--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	1.7e-81	44.4
WP_096471349.1\|1127960_1128860_+	DMT family transporter	NA	NA	NA	NA
WP_096471350.1\|1128973_1129582_+	TIGR00645 family protein	K4K6D8	Caulobacter_phage	2.7e-22	32.9

DBSCAN-SWA_75

1170514 : 1171105

Lactobacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471382.1\|1170514_1171105_-	NUDIX hydrolase	A0A2K9VDH1	Lactobacillus_phage	6.0e-11	36.7

DBSCAN-SWA_76

1196630 : 1210588

Micromonas_sp._RCC1109_virus(20.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047898617.1\|1196630_1198175_-	2-isopropylmalate synthase	E5EQ69	Micromonas_sp._RCC1109_virus	7.3e-08	24.9
WP_096471394.1\|1198493_1199366_-	CDP-diacylglycerol--serine O-phosphatidyltransferase	NA	NA	NA	NA
WP_047898619.1\|1199381_1200026_-	phosphatidylserine decarboxylase	A0A1V0SDU9	Indivirus	3.1e-13	29.8
WP_047898620.1\|1200153_1201170_-	ketol-acid reductoisomerase	NA	NA	NA	NA
WP_006750445.1\|1201274_1201766_-	acetolactate synthase small subunit	NA	NA	NA	NA
WP_047898621.1\|1201877_1203641_-	acetolactate synthase 3 catalytic subunit	G9E525	Ostreococcus_lucimarinus_virus	1.7e-29	29.7
WP_047898622.1\|1203997_1204561_+	RNA polymerase sigma factor	NA	NA	NA	NA
WP_096471395.1\|1204557_1204983_+	DUF3619 family protein	NA	NA	NA	NA
WP_096471396.1\|1205009_1205765_+	DUF3106 domain-containing protein	NA	NA	NA	NA
WP_096471397.1\|1205771_1206278_+	RDD family protein	NA	NA	NA	NA
WP_096471398.1\|1206502_1207441_+	UDP-2,3-diacylglucosamine diphosphatase	A0A218MKA7	uncultured_virus	1.6e-66	48.5
WP_096471399.1\|1207470_1208505_+	glycosyltransferase family 1 protein	NA	NA	NA	NA
WP_047898628.1\|1208501_1209038_+	diacylglycerol kinase	NA	NA	NA	NA
WP_096471400.1\|1209251_1210010_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_096471401.1\|1210006_1210588_+	TIGR00730 family Rossman fold protein	A0A1G5S9X4	Enterococcus_phage	2.6e-14	34.2

DBSCAN-SWA_77

1213678 : 1214296

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471404.1\|1213678_1214296_-	DUF924 domain-containing protein	A0A1V0SIY0	Klosneuvirus	3.0e-21	33.3

DBSCAN-SWA_78

1220646 : 1226339

Hokovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471408.1\|1220646_1223490_-	DUF4118 domain-containing protein	A0A1V0SGX0	Hokovirus	8.2e-05	22.3
WP_096471409.1\|1223654_1224236_-	potassium-transporting ATPase subunit KdpC	NA	NA	NA	NA
WP_096471410.1\|1224254_1226339_-	potassium-transporting ATPase subunit KdpB	M1HBF8	Paramecium_bursaria_Chlorella_virus	4.4e-24	26.2

DBSCAN-SWA_79

1244956 : 1246738

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471425.1\|1244956_1246738_-	lipid A export permease/ATP-binding protein MsbA	W8CYL7	Bacillus_phage	1.2e-43	25.6

DBSCAN-SWA_80

1252937 : 1260359

Streptomyces_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471431.1\|1252937_1256471_-	DNA polymerase III subunit alpha	A0A0K1Y906	Streptomyces_phage	1.0e-182	36.8
WP_096471433.1\|1256844_1257699_+	sulfurtransferase	NA	NA	NA	NA
WP_096471434.1\|1257718_1258612_+\|tRNA	tRNA glutamyl-Q(34) synthetase GluQRS	NA	NA	NA	NA
WP_096471435.1\|1258787_1260359_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	8.9e-54	35.6

DBSCAN-SWA_81

1263554 : 1268225

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471439.1\|1263554_1268225_+	cell division protein FtsK	S5VNE3	Mycobacterium_phage	2.2e-84	49.3

DBSCAN-SWA_82

1282085 : 1283039

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471446.1\|1282085_1283039_+	transaldolase	A0A0E3F0E2	Synechococcus_phage	6.3e-10	32.6

DBSCAN-SWA_83

1288828 : 1290727

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471453.1\|1288828_1290727_-	molecular chaperone HtpG	A0A1B1ISV4	uncultured_Mediterranean_phage	2.4e-117	37.8

DBSCAN-SWA_84

1297169 : 1299509

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471459.1\|1297169_1299509_+	EAL domain-containing protein	A0A127AWB9	Bacillus_phage	9.3e-15	34.6

DBSCAN-SWA_85

1303189 : 1317301

Bacillus_virus(33.33%)

integrase

attL 1292876:1292889|attR 1315018:1315031

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1292876:1292889	attL	NA	NA	NA	NA
WP_096471464.1\|1303189_1305511_-	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	3.0e-82	37.0
WP_096471465.1\|1305578_1307561_-	type IIA DNA topoisomerase subunit B	G3M9Z3	Bacillus_virus	1.6e-92	34.8
WP_096471466.1\|1307803_1309753_-	ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	1.4e-48	28.9
WP_096471467.1\|1310043_1310448_-	DUF4399 domain-containing protein	NA	NA	NA	NA
WP_034190709.1\|1310647_1310830_+	rubredoxin	NA	NA	NA	NA
WP_096471468.1\|1311200_1312415_+\|integrase	integrase arm-type DNA-binding domain-containing protein	Q7M297	Enterobacteria_phage	1.2e-85	41.1
WP_172902914.1\|1312510_1313581_-	ParA family protein	H2BD62	Pseudomonas_phage	1.6e-46	36.0
WP_172902915.1\|1314439_1317301_-	DUF927 domain-containing protein	A0A1B0VP75	Pseudomonas_phage	3.9e-71	35.8
1315018:1315031	attR	NA	NA	NA	NA

DBSCAN-SWA_86

1322014 : 1322590

Aeromonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471472.1\|1322014_1322590_+	recombinase family protein	A0A219Y912	Aeromonas_phage	3.9e-23	40.7

DBSCAN-SWA_87

1330951 : 1334080

Mycobacterium_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471481.1\|1330951_1332004_-\|transposase	transposase	A0A1C9LZZ3	Mycobacterium_phage	1.4e-31	40.8
WP_096471482.1\|1332096_1333464_+	MFS transporter	NA	NA	NA	NA
WP_096473056.1\|1333489_1334080_-	AAA family ATPase	A0A219VHB7	Ochrobactrum_phage	2.5e-25	61.6

DBSCAN-SWA_88

1337225 : 1338563

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034184771.1\|1337225_1338563_-	nitrate/sulfonate/bicarbonate ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.4e-31	38.5

DBSCAN-SWA_89

1342457 : 1343183

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047898732.1\|1342457_1343183_-	response regulator	W8CYM9	Bacillus_phage	1.1e-30	35.8

DBSCAN-SWA_90

1347523 : 1348303

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471492.1\|1347523_1348303_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.9e-17	32.3

DBSCAN-SWA_91

1352380 : 1354117

Agrobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096473059.1\|1352380_1354117_-	NAD+ synthase	A0A2L0UZF5	Agrobacterium_phage	3.0e-87	35.6

DBSCAN-SWA_92

1358995 : 1360463

Invertebrate_iridovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471496.1\|1358995_1359880_+	GIY-YIG nuclease family protein	W8W2G4	Invertebrate_iridovirus	1.9e-08	44.4
WP_011352863.1\|1359935_1360463_-	inorganic diphosphatase	A0A2H4J8U1	uncultured_Caudovirales_phage	8.4e-49	52.0

DBSCAN-SWA_93

1380810 : 1381494

Acanthocystis_turfacea_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096473061.1\|1380810_1381494_+	HAD family phosphatase	M1IMD4	Acanthocystis_turfacea_Chlorella_virus	3.9e-06	32.6

DBSCAN-SWA_94

1384790 : 1385360

Pseudomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471512.1\|1384790_1385360_-	dCTP deaminase	S5VM63	Pseudomonas_phage	4.5e-72	70.6

DBSCAN-SWA_95

1388607 : 1390770

Indivirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471515.1\|1388607_1390770_+\|tRNA	methionine--tRNA ligase	A0A1V0SDF2	Indivirus	6.1e-53	28.6

DBSCAN-SWA_96

1399742 : 1400402

Vibrio_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471521.1\|1399742_1400402_-	ParA family protein	A2I303	Vibrio_virus	1.7e-14	34.4

DBSCAN-SWA_97

1410726 : 1412643

Acinetobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471533.1\|1410726_1412643_-	TonB-dependent receptor	A0A0P0I887	Acinetobacter_phage	1.4e-05	32.0

DBSCAN-SWA_98

1421190 : 1422702

Mycoplasma_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048250340.1\|1421190_1422702_-	leucyl aminopeptidase	Q6GYZ8	Mycoplasma_phage	1.4e-51	40.1

DBSCAN-SWA_99

1426380 : 1427697

Hokovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471544.1\|1426380_1427697_-	sulfate adenylyltransferase subunit 1	A0A1V0SGC3	Hokovirus	1.6e-35	30.0

DBSCAN-SWA_100

1443305 : 1447421

Klosneuvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471559.1\|1443305_1444490_+	acetylornithine transaminase	A0A1V0SKB7	Klosneuvirus	7.8e-26	27.0
WP_096471560.1\|1444503_1444959_+	GNAT family acetyltransferase	NA	NA	NA	NA
WP_096471561.1\|1444983_1445655_-	YukJ family protein	NA	NA	NA	NA
WP_096471562.1\|1445928_1446645_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.1e-10	26.9
WP_096471563.1\|1446644_1447421_-	ABC transporter ATP-binding protein	M1H3A1	Paramecium_bursaria_Chlorella_virus	8.4e-05	25.9

DBSCAN-SWA_101

1462055 : 1474882

Prochlorococcus_phage(14.29%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_043189977.1\|1462055_1462718_-	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	3.3e-26	40.0
WP_096471573.1\|1462841_1463834_+	bifunctional riboflavin kinase/FAD synthetase	NA	NA	NA	NA
WP_096471574.1\|1463935_1466773_+\|tRNA	isoleucine--tRNA ligase	A0A1V0SJ93	Klosneuvirus	9.7e-83	26.4
WP_047898830.1\|1466775_1467276_+	lipoprotein signal peptidase	NA	NA	NA	NA
WP_096471575.1\|1467343_1468555_+	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	1.6e-42	32.4
WP_065499366.1\|1468610_1469057_+	dUTP diphosphatase	Q2NP83	Xanthomonas_phage	3.5e-48	63.7
WP_096471576.1\|1469111_1469882_-	hypothetical protein	NA	NA	NA	NA
WP_096471577.1\|1470039_1471419_-	amino acid permease	NA	NA	NA	NA
WP_096471578.1\|1471522_1473823_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	5.0e-162	40.4
WP_006398529.1\|1473819_1474134_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A218MMY6	uncultured_virus	4.4e-13	44.6
WP_006478030.1\|1474678_1474882_+	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	2.6e-22	78.8

DBSCAN-SWA_102

1480199 : 1485800

Phage_21(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034178829.1\|1480199_1481456_-	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	1.2e-11	63.0
WP_034178831.1\|1481732_1482311_+	pseudouridine synthase	NA	NA	NA	NA
WP_072444916.1\|1482591_1482810_+	hypothetical protein	NA	NA	NA	NA
WP_096471582.1\|1482970_1483471_+	DUF192 domain-containing protein	A0A1B1IUW8	uncultured_Mediterranean_phage	4.1e-13	40.2
WP_096471583.1\|1483688_1485800_+	elongation factor G	E4ZFJ7	Streptococcus_phage	1.3e-55	26.4

DBSCAN-SWA_103

1500279 : 1502464

Bacillus_thuringiensis_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011352986.1\|1500279_1500858_-	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	1.9e-41	43.2
WP_096471595.1\|1501084_1502464_-	exodeoxyribonuclease VII large subunit	A0A1B3AYB4	Gordonia_phage	1.8e-29	25.6

DBSCAN-SWA_104

1510897 : 1511827

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047898860.1\|1510897_1511827_+	ornithine carbamoyltransferase	M1HWF9	Paramecium_bursaria_Chlorella_virus	2.8e-23	27.7

DBSCAN-SWA_105

1516853 : 1529323

Catovirus(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096473066.1\|1516853_1518416_+	AMP-binding protein	A0A1V0SBX8	Catovirus	2.6e-13	25.2
WP_096471606.1\|1518477_1519428_-	site-specific tyrosine recombinase XerD	A0A0K2CP59	Brevibacillus_phage	8.1e-26	29.5
WP_034190552.1\|1519427_1519895_-	methylated-DNA--[protein]-cysteine S-methyltransferase	NA	NA	NA	NA
WP_096471607.1\|1519959_1521195_-\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_096471608.1\|1521212_1521764_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_096471609.1\|1521745_1523272_+	N-acetylmuramoyl-L-alanine amidase	Q5YA51	Bacillus_phage	2.8e-12	28.1
WP_172902950.1\|1523326_1524205_-	EamA family transporter	NA	NA	NA	NA
WP_096471611.1\|1524465_1525347_+	pirin family protein	NA	NA	NA	NA
WP_096471612.1\|1525399_1526248_+	thioredoxin	A0A1X9I9P5	Staphylococcus_phage	2.2e-14	37.8
WP_096471613.1\|1526350_1527208_-\|tRNA	tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA	S4VW33	Pandoravirus	8.4e-14	33.1
WP_096471614.1\|1527336_1527981_+	pyridoxamine 5'-phosphate oxidase	NA	NA	NA	NA
WP_096471615.1\|1528102_1529323_+	class I SAM-dependent methyltransferase	A0A2I2L5L3	Orpheovirus	1.3e-44	33.1

DBSCAN-SWA_106

1542432 : 1546654

Ostreococcus_lucimarinus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471625.1\|1542432_1544040_-	benzoylformate decarboxylase	G9E4W7	Ostreococcus_lucimarinus_virus	1.4e-06	37.6
WP_096471626.1\|1544139_1545051_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_096471627.1\|1545244_1546654_+	mannitol dehydrogenase family protein	H8ZJP8	Ostreococcus_tauri_virus	1.5e-44	30.5

DBSCAN-SWA_107

1551766 : 1553629

Planktothrix_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471631.1\|1551766_1552876_-	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	G9BWD6	Planktothrix_phage	1.0e-24	34.8
WP_096471632.1\|1552930_1553629_-	HAD family phosphatase	M1IMD4	Acanthocystis_turfacea_Chlorella_virus	1.3e-07	45.6

DBSCAN-SWA_108

1561861 : 1569247

Staphylococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471640.1\|1561861_1562752_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.0e-10	23.3
WP_096471641.1\|1562744_1563527_+	metal ABC transporter permease	NA	NA	NA	NA
WP_096471642.1\|1563654_1564503_-	S-formylglutathione hydrolase	NA	NA	NA	NA
WP_034178897.1\|1564519_1565626_-	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase	A0A0K0KVL7	Prochlorococcus_phage	2.7e-33	29.3
WP_157776338.1\|1565807_1565966_+	hypothetical protein	NA	NA	NA	NA
WP_096471643.1\|1565949_1567431_-	carbohydrate kinase	NA	NA	NA	NA
WP_172902919.1\|1567481_1567865_+	hypothetical protein	NA	NA	NA	NA
WP_047898904.1\|1567870_1569247_+	purine permease	Q9KX94	Enterobacteria_phage	1.3e-29	30.7

DBSCAN-SWA_109

1581032 : 1583975

uncultured_Mediterranean_phage(50.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471655.1\|1581032_1582517_-\|protease	DegQ family serine endoprotease	A0A1B1IT49	uncultured_Mediterranean_phage	1.7e-25	30.7
WP_072442766.1\|1582628_1583975_-	HAMP domain-containing protein	W8CYF6	Bacillus_phage	4.0e-18	29.5

DBSCAN-SWA_110

1589094 : 1592889

Pandoravirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471660.1\|1589094_1590123_-	threonylcarbamoyl-AMP synthase	S4VW33	Pandoravirus	1.5e-41	39.2
WP_096471661.1\|1590134_1591331_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_096471662.1\|1591411_1591933_-	5-(carboxyamino)imidazole ribonucleotide mutase	NA	NA	NA	NA
WP_096471663.1\|1591998_1592889_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0M4JBD3	Mollivirus	2.4e-56	39.4

DBSCAN-SWA_111

1606059 : 1614514

Pseudomonas_phage(33.33%)

integrase

attL 1604150:1604164|attR 1608223:1608237

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1604150:1604164	attL	NA	NA	NA	NA
WP_096471672.1\|1606059_1607043_+\|integrase	site-specific integrase	W6MYA3	Pseudomonas_phage	1.9e-41	34.3
WP_096473069.1\|1607138_1607771_-	hypothetical protein	NA	NA	NA	NA
WP_096471673.1\|1608076_1608679_+	hypothetical protein	NA	NA	NA	NA
1608223:1608237	attR	NA	NA	NA	NA
WP_096471674.1\|1608692_1608980_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_096471675.1\|1608988_1610332_-	DUF3396 domain-containing protein	E5E3X8	Burkholderia_phage	5.0e-13	24.1
WP_096471676.1\|1610370_1611636_-	VRR-NUC domain-containing protein	NA	NA	NA	NA
WP_096471677.1\|1611661_1614514_-	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	4.5e-11	37.8

DBSCAN-SWA_112

1628655 : 1631343

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471688.1\|1628655_1631343_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	5.2e-62	24.7

DBSCAN-SWA_113

1639977 : 1640682

Pseudomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471694.1\|1639977_1640682_-	TerC family protein	A0A2R2YAT9	Pseudomonas_phage	1.5e-37	42.3

DBSCAN-SWA_114

1644644 : 1646634

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471698.1\|1644644_1645715_-	recombinase RecA	A0A0S2MVG1	Bacillus_phage	5.1e-117	63.4
WP_096471699.1\|1645905_1646634_+	response regulator transcription factor	Q6XM27	Feldmannia_irregularis_virus	9.4e-06	29.2

DBSCAN-SWA_115

1653956 : 1658555

Burkholderia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471706.1\|1653956_1654241_-	PAAR domain-containing protein	R4JMI1	Burkholderia_phage	4.1e-10	40.4
WP_096471707.1\|1654386_1655589_-	porin	NA	NA	NA	NA
WP_096471708.1\|1655705_1657184_-	hypothetical protein	NA	NA	NA	NA
WP_096471709.1\|1657238_1658555_-	MFS transporter	Q6JIH2	Burkholderia_virus	3.7e-77	38.5

DBSCAN-SWA_116

1665250 : 1666399

Oenococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047901054.1\|1665250_1666399_+	galactonate dehydratase	Q6A202	Oenococcus_phage	1.1e-56	33.9

DBSCAN-SWA_117

1670076 : 1671516

Diachasmimorpha_longicaudata_entomopoxvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471716.1\|1670076_1671516_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	6.3e-54	34.0

DBSCAN-SWA_118

1675082 : 1675862

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006493999.1\|1675082_1675862_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.4e-23	29.8

DBSCAN-SWA_119

1680202 : 1680919

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471721.1\|1680202_1680919_+	aquaporin family protein	M1HJ77	Paramecium_bursaria_Chlorella_virus	2.8e-23	40.4

DBSCAN-SWA_120

1688267 : 1689793

Paramecium_bursaria_Chlorella_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096473081.1\|1688267_1688954_+	HAD family hydrolase	A7J6N1	Paramecium_bursaria_Chlorella_virus	9.4e-08	30.7
WP_047898967.1\|1689082_1689793_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	6.0e-42	44.2

DBSCAN-SWA_121

1695044 : 1696088

Pseudomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471727.1\|1695044_1696088_+	PhoH family protein	A0A0S0MVD6	Pseudomonas_phage	6.4e-48	44.6

DBSCAN-SWA_122

1717927 : 1719799

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471744.1\|1717927_1719799_-	ABC transporter ATP-binding protein/permease	W8CYL7	Bacillus_phage	7.2e-42	27.2

DBSCAN-SWA_123

1731122 : 1736372

Tupanvirus(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034179002.1\|1731122_1732925_-\|tRNA	aspartate--tRNA ligase	A0A2K9L0E9	Tupanvirus	2.2e-19	30.2
WP_047898998.1\|1732992_1733643_-	DUF502 domain-containing protein	A0A2I7S9X1	Vibrio_phage	1.4e-13	27.9
WP_047898999.1\|1733704_1734055_-	FmdB family transcriptional regulator	NA	NA	NA	NA
WP_096471753.1\|1734150_1734777_-	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_096471754.1\|1734794_1736372_-	ubiquinone biosynthesis regulatory protein kinase UbiB	A0A2P0VMP1	Tetraselmis_virus	1.7e-28	26.5

DBSCAN-SWA_124

1746111 : 1746942

Vibrio_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471760.1\|1746111_1746942_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	A0A2I7SAX1	Vibrio_phage	5.2e-37	36.2

DBSCAN-SWA_125

1756950 : 1758165

Escherichia_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471770.1\|1756950_1758165_-\|transposase	transposase	A0A077SL42	Escherichia_phage	7.2e-128	56.5

DBSCAN-SWA_126

1770855 : 1771572

Chrysochromulina_ericina_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471782.1\|1770855_1771572_-	3-oxoacyl-ACP reductase FabG	A0A0N9R355	Chrysochromulina_ericina_virus	5.2e-09	26.0

DBSCAN-SWA_127

1788975 : 1804229

Burkholderia_virus(14.29%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471798.1\|1788975_1789530_-	single-stranded DNA-binding protein	Q6V7S6	Burkholderia_virus	8.0e-50	89.0
WP_034179048.1\|1789632_1790820_-	MFS transporter	NA	NA	NA	NA
WP_096471799.1\|1791067_1793953_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	7.3e-304	54.5
WP_172902923.1\|1794206_1795292_+	hypothetical protein	NA	NA	NA	NA
WP_096471800.1\|1795383_1796268_-	formyltetrahydrofolate deformylase	M4QRX9	Synechococcus_phage	1.9e-13	34.8
WP_096473087.1\|1796330_1797197_-	DUF4743 domain-containing protein	NA	NA	NA	NA
WP_047899043.1\|1797202_1797817_-	LysE family translocator	NA	NA	NA	NA
WP_096471801.1\|1797856_1798423_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	1.7e-26	40.4
WP_096473088.1\|1798500_1800507_-	monovalent cation:proton antiporter family protein	NA	NA	NA	NA
WP_096471802.1\|1800632_1801616_+	KpsF/GutQ family sugar-phosphate isomerase	A0A2P0VNK5	Tetraselmis_virus	6.9e-44	37.9
WP_047899045.1\|1801615_1802152_+	HAD family hydrolase	E3T535	Cafeteria_roenbergensis_virus	3.5e-10	28.0
WP_096471803.1\|1802155_1802770_+	LPS export ABC transporter periplasmic protein LptC	NA	NA	NA	NA
WP_096471804.1\|1802790_1803456_+	lipopolysaccharide transport periplasmic protein LptA	NA	NA	NA	NA
WP_096471805.1\|1803452_1804229_+	LPS export ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	1.1e-17	30.1

DBSCAN-SWA_128

1808295 : 1809204

Corynebacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471807.1\|1808295_1809204_+	RNase adapter RapZ	A0A1P8D5W0	Corynebacterium_phage	1.8e-06	29.8

DBSCAN-SWA_129

1815577 : 1820111

uncultured_Mediterranean_phage(66.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034179069.1\|1815577_1816534_+	ribose-phosphate pyrophosphokinase	A0A2K9L2G2	Tupanvirus	2.6e-40	34.3
WP_096471812.1\|1816694_1817300_+	50S ribosomal protein L25/general stress protein Ctc	NA	NA	NA	NA
WP_096471813.1\|1817420_1818020_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_096471814.1\|1818135_1819203_+	histidinol-phosphate transaminase	NA	NA	NA	NA
WP_071335108.1\|1819287_1819554_-	YfhL family 4Fe-4S dicluster ferredoxin	A0A1B1IWY9	uncultured_Mediterranean_phage	3.9e-18	55.8
WP_021163047.1\|1819613_1820111_-	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	2.0e-31	45.9

DBSCAN-SWA_130

1828053 : 1829920

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471820.1\|1828053_1828623_-	acyloxyacyl hydrolase	A0A2H4J0I5	uncultured_Caudovirales_phage	2.0e-11	31.8
WP_096471822.1\|1828984_1829920_+	RNA polymerase sigma factor RpoH	A0A248SJA5	Salicola_phage	2.4e-38	37.1

DBSCAN-SWA_131

1834039 : 1850846

Staphylococcus_phage(20.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471827.1\|1834039_1836523_+	carbohydate-binding domain-containing protein	A0A076G5S5	Staphylococcus_phage	2.2e-06	31.9
WP_065499163.1\|1836688_1838452_-	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_096471828.1\|1838539_1841122_-	phosphoenolpyruvate--protein phosphotransferase	A0A1V0SGR7	Hokovirus	3.8e-09	28.8
WP_096471829.1\|1841137_1842154_-	SIS domain-containing protein	F2Y1G4	Organic_Lake_phycodnavirus	6.1e-11	24.1
WP_069746988.1\|1842146_1843250_-	N-acetylglucosamine-6-phosphate deacetylase	NA	NA	NA	NA
WP_047899075.1\|1843358_1844093_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_096471830.1\|1844420_1847624_-	error-prone DNA polymerase	A0A096XUX6	Cronobacter_phage	7.2e-58	29.2
WP_096471831.1\|1847630_1849118_-	DNA polymerase Y family protein	NA	NA	NA	NA
WP_047899078.1\|1849050_1849758_-	translesion DNA synthesis-associated protein ImuA	NA	NA	NA	NA
WP_096471832.1\|1850051_1850846_-	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	2.3e-05	26.2

DBSCAN-SWA_132

1854645 : 1856265

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096473090.1\|1854645_1856265_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	8.2e-10	53.8

DBSCAN-SWA_133

1863572 : 1865180

Flavobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021163746.1\|1863572_1865180_-	cytochrome c oxidase subunit I	R9VX24	Flavobacterium_phage	2.0e-08	37.7

DBSCAN-SWA_134

1870049 : 1872541

Turbot_reddish_body_iridovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471847.1\|1870049_1870574_-	O-acetyl-ADP-ribose deacetylase	E2CTW8	Turbot_reddish_body_iridovirus	2.9e-33	46.7
WP_096471848.1\|1870666_1871665_-	NAD(P)-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_059681636.1\|1871690_1872173_-	protein-export chaperone SecB	NA	NA	NA	NA
WP_034179116.1\|1872280_1872541_-	glutaredoxin 3	V9QKN6	Rhizobium_phage	4.5e-11	46.8

DBSCAN-SWA_135

1876779 : 1878552

Hokovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096473092.1\|1876779_1878552_-	phosphoenolpyruvate--protein phosphotransferase	A0A1V0SGR7	Hokovirus	5.6e-12	27.3

DBSCAN-SWA_136

1902717 : 1906398

Diachasmimorpha_longicaudata_entomopoxvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471865.1\|1902717_1904592_+	gamma-glutamyltransferase	Q5GF27	Diachasmimorpha_longicaudata_entomopoxvirus	1.5e-10	27.0
WP_096471866.1\|1904644_1905604_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_096471867.1\|1905600_1906398_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.4e-31	40.4

DBSCAN-SWA_137

1909944 : 1913511

Burkholderia_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471870.1\|1909944_1910931_+	transcriptional regulator GcvA	Q6JIH3	Burkholderia_virus	1.1e-30	32.4
WP_011546305.1\|1910914_1911223_-	YbeD family protein	NA	NA	NA	NA
WP_096471871.1\|1911222_1912149_-	D-amino acid aminotransferase	NA	NA	NA	NA
WP_096471872.1\|1912197_1913511_-	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	2.6e-67	39.0

DBSCAN-SWA_138

1918145 : 1919075

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471875.1\|1918145_1919075_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-21	33.0

DBSCAN-SWA_139

1925094 : 1925712

Burkholderia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471881.1\|1925094_1925712_-	hypothetical protein	R4JJZ3	Burkholderia_phage	2.4e-79	67.5

DBSCAN-SWA_140

1929456 : 1929942

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471886.1\|1929456_1929942_-	D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase	A0A1B1IUK5	uncultured_Mediterranean_phage	6.6e-16	32.8

DBSCAN-SWA_141

1938575 : 1939643

Dickeya_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034179166.1\|1938575_1939643_+	homocysteine S-methyltransferase family protein	A0A140XBC7	Dickeya_phage	1.4e-10	48.4

DBSCAN-SWA_142

1949565 : 1951215

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471897.1\|1949565_1951215_+	ABC-F family ATP-binding cassette domain-containing protein	A0A1B0RXA0	Streptococcus_phage	1.7e-18	24.2

DBSCAN-SWA_143

1955347 : 1956025

Bacillus_thuringiensis_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471900.1\|1955347_1956025_+	SDR family oxidoreductase	Q56AQ6	Bacillus_thuringiensis_phage	5.1e-06	30.3

DBSCAN-SWA_144

1959760 : 1960945

Emiliania_huxleyi_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096473098.1\|1959760_1960945_+	8-amino-7-oxononanoate synthase	V5LQ39	Emiliania_huxleyi_virus	4.1e-19	26.5

DBSCAN-SWA_145

1986004 : 1986937

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_065499064.1\|1986004_1986937_+	hydroxymethylglutaryl-CoA lyase	A0A1V0SKU2	Klosneuvirus	3.3e-40	34.3

DBSCAN-SWA_146

2004824 : 2009187

Escherichia_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471932.1\|2004824_2005817_+\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	1.1e-105	69.4
WP_096471933.1\|2005952_2007314_+	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L277	Tupanvirus	5.4e-31	34.2
WP_096471934.1\|2007369_2009187_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	2.4e-143	47.2

DBSCAN-SWA_147

2019862 : 2022014

Bacillus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471942.1\|2019862_2021017_+	polyamine ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.9e-24	33.0
WP_096471943.1\|2021027_2022014_+	ABC transporter permease subunit	Q6GZ02	Mycoplasma_phage	5.9e-11	23.4

DBSCAN-SWA_148

2033928 : 2035236

Enterobacteria_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471953.1\|2033928_2035236_-	pyrimidine utilization transport protein G	Q9KX94	Enterobacteria_phage	2.4e-161	70.8

DBSCAN-SWA_149

2039939 : 2040938

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471957.1\|2039939_2040938_-	flagellar assembly peptidoglycan hydrolase FlgJ	A0A160LKR7	Bacillus_phage	1.8e-15	43.1

DBSCAN-SWA_150

2054885 : 2056127

Sinorhizobium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471971.1\|2054885_2056127_-	multifunctional CCA addition/repair protein	A0A0F6YPT7	Sinorhizobium_phage	1.3e-79	42.2

DBSCAN-SWA_151

2065432 : 2067489

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471980.1\|2065432_2066446_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.8e-18	30.7
WP_096471981.1\|2066442_2067489_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-17	33.3

DBSCAN-SWA_152

2071588 : 2072896

Burkholderia_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096471984.1\|2071588_2072896_-	MFS transporter	Q6JIH2	Burkholderia_virus	1.8e-95	45.4

DBSCAN-SWA_153

2096122 : 2097763

Orpheovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472005.1\|2096122_2097763_-	GMC family oxidoreductase N-terminal domain-containing protein	A0A2I2L3D3	Orpheovirus	1.1e-35	28.8

DBSCAN-SWA_154

2106816 : 2112440

Staphylococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006482984.1\|2106816_2108004_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.7e-121	61.0
WP_096472014.1\|2108269_2109154_+	lipid A biosynthesis lauroyl acyltransferase	A0A1W6JP29	Morganella_phage	1.6e-28	30.1
WP_096472015.1\|2109184_2109487_-	HigA family addiction module antidote protein	NA	NA	NA	NA
WP_096472016.1\|2109875_2110745_+	diaminopimelate epimerase	NA	NA	NA	NA
WP_096472017.1\|2110782_2111508_+	DUF484 family protein	NA	NA	NA	NA
WP_172902925.1\|2111519_2112440_+	tyrosine recombinase XerC	A0A166YH27	Gordonia_phage	1.0e-12	31.7

DBSCAN-SWA_155

2116700 : 2118044

Erwinia_phage(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472020.1\|2116700_2118044_+\|protease	ATP-dependent protease ATPase subunit HslU	A0A191ZC11	Erwinia_phage	2.6e-41	28.8

DBSCAN-SWA_156

2132126 : 2134086

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047899314.1\|2132126_2133179_+	NAD(P)-dependent alcohol dehydrogenase	A0A2K9L7I1	Tupanvirus	4.7e-83	43.8
WP_047899315.1\|2133312_2134086_-	exodeoxyribonuclease III	R4TWA8	Phaeocystis_globosa_virus	2.3e-26	31.6

DBSCAN-SWA_157

2147030 : 2148944

Vibrio_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472034.1\|2147030_2147483_-	6-carboxytetrahydropterin synthase QueD	A0A088FAL2	Vibrio_phage	1.7e-13	30.8
WP_021163976.1\|2147501_2148134_-	7-carboxy-7-deazaguanine synthase	R4TAH8	Halovirus	5.1e-08	35.1
WP_096472035.1\|2148209_2148944_-	7-cyano-7-deazaguanine synthase QueC	A0A1B0Z0B4	Vibrio_phage	2.8e-50	43.5

DBSCAN-SWA_158

2156434 : 2165325

Prochlorococcus_phage(20.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472040.1\|2156434_2157418_-\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	1.2e-08	36.2
WP_096472041.1\|2157452_2157956_-	peptide deformylase	A0A067XQZ3	Caulobacter_phage	1.2e-12	33.6
WP_096472042.1\|2158027_2159470_+	DNA-protecting protein DprA	S6BFL3	Thermus_phage	4.1e-21	32.8
WP_096472043.1\|2159506_2159887_+	thioredoxin family protein	NA	NA	NA	NA
WP_096472044.1\|2160080_2162705_+	DNA topoisomerase III	A0A0G2YA05	Acanthamoeba_polyphaga_mimivirus	2.7e-18	24.3
WP_096472045.1\|2162835_2163885_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_096472046.1\|2164311_2165325_+	D-2-hydroxyacid dehydrogenase family protein	M1HBE3	Paramecium_bursaria_Chlorella_virus	3.3e-09	22.2

DBSCAN-SWA_159

2169753 : 2170512

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472050.1\|2169753_2170512_-	amino acid ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.3e-13	35.1

DBSCAN-SWA_160

2187332 : 2188424

Acanthamoeba_polyphaga_mimivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472061.1\|2187332_2188424_-	bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	1.7e-19	36.2

DBSCAN-SWA_161

2198401 : 2211396

Burkholderia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009694594.1\|2198401_2198668_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	2.5e-17	53.6
WP_021157986.1\|2198743_2199205_-	ribonuclease P protein component	NA	NA	NA	NA
WP_004198824.1\|2199220_2199355_-	50S ribosomal protein L34	NA	NA	NA	NA
WP_096472068.1\|2199665_2201342_+	chromosomal replication initiator protein DnaA	NA	NA	NA	NA
WP_006756934.1\|2201511_2202618_+	DNA polymerase III subunit beta	R9TRR6	Rhizobium_phage	2.4e-45	31.4
WP_096472069.1\|2202809_2205284_+	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	1.0e-112	34.3
WP_096472070.1\|2207170_2208388_-	restriction endonuclease	E5E3X4	Burkholderia_phage	1.9e-144	63.4
WP_096472071.1\|2208463_2209378_+	hypothetical protein	NA	NA	NA	NA
WP_096472072.1\|2209545_2210043_-	DNA mismatch endonuclease Vsr	E5E3X5	Burkholderia_phage	7.0e-45	55.3
WP_096472073.1\|2210109_2211396_-	DNA (cytosine-5-)-methyltransferase	E5E3X6	Burkholderia_phage	7.9e-149	66.6

DBSCAN-SWA_162

2232816 : 2237861

Erysipelothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472088.1\|2232816_2235843_-	DEAD/DEAH box helicase family protein	A0A2K5B256	Erysipelothrix_phage	1.7e-173	37.8
WP_096472089.1\|2235842_2237861_-	site-specific DNA-methyltransferase	A0A2K5B255	Erysipelothrix_phage	2.0e-82	31.3

DBSCAN-SWA_163

2242646 : 2243444

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472093.1\|2242646_2243444_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	7.0e-31	35.8

DBSCAN-SWA_164

2268420 : 2270738

Ralstonia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472115.1\|2268420_2268870_+	lytic transglycosylase domain-containing protein	A0A0K2QQJ4	Ralstonia_phage	2.6e-14	38.6
WP_096472116.1\|2269028_2270330_+	GTP-binding protein	NA	NA	NA	NA
WP_006401505.1\|2270459_2270738_-	HU family DNA-binding protein	A4JWM7	Burkholderia_virus	1.1e-20	61.8

DBSCAN-SWA_165

2286907 : 2289821

Catovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472125.1\|2286907_2288593_+	GMC family oxidoreductase N-terminal domain-containing protein	A0A1V0S9M4	Catovirus	5.4e-57	30.2
WP_006477266.1\|2289041_2289821_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	7.2e-12	24.0

DBSCAN-SWA_166

2297387 : 2299927

Brazilian_cedratvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472133.1\|2297387_2299172_+	branched-chain amino acid ABC transporter ATP-binding protein/permease	A0A2R8FG22	Brazilian_cedratvirus	6.7e-13	26.9
WP_096472134.1\|2299171_2299927_+	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	1.4e-09	25.3

DBSCAN-SWA_167

2303259 : 2304964

Natrialba_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472136.1\|2303259_2304039_+	ParA family protein	Q8JL10	Natrialba_phage	1.6e-19	33.9
WP_011546803.1\|2304070_2304964_+	ParB/RepB/Spo0J family partition protein	I3NLC2	Bifidobacterium_phage	2.2e-17	38.0

DBSCAN-SWA_168

2314542 : 2316270

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472141.1\|2314542_2316270_+	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	3.9e-34	30.9

DBSCAN-SWA_169

2327408 : 2328917

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472146.1\|2327408_2328917_-	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	2.1e-31	30.6

DBSCAN-SWA_170

2336254 : 2338819

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472152.1\|2336254_2338819_+	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	1.6e-132	45.0

DBSCAN-SWA_171

2359765 : 2362693

Prochlorococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472170.1\|2359765_2362693_-	aminomethyl-transferring glycine dehydrogenase	M4QFZ1	Prochlorococcus_phage	3.1e-257	51.0

DBSCAN-SWA_172

2367639 : 2369727

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_065498804.1\|2367639_2369727_+	UvrD-helicase domain-containing protein	A7KV33	Bacillus_phage	3.1e-102	35.8

DBSCAN-SWA_173

2373718 : 2378247

Klosneuvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472175.1\|2373718_2377087_-	glycosyltransferase	A0A1V0SLJ0	Klosneuvirus	7.6e-10	24.5
WP_096472176.1\|2377089_2378247_-	dTDP-4-amino-4,6-dideoxygalactose transaminase	A0A0F7LAY0	uncultured_marine_virus	1.4e-19	34.3

DBSCAN-SWA_174

2397188 : 2398526

uncultured_Mediterranean_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472191.1\|2397188_2397929_-	aquaporin Z	A0A1B1ISL4	uncultured_Mediterranean_phage	8.0e-05	50.8
WP_096472192.1\|2398229_2398526_+	H-NS histone family protein	F8TUP5	EBPR_podovirus	4.3e-10	40.0

DBSCAN-SWA_175

2406705 : 2412002

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472200.1\|2406705_2408679_+	Tar ligand binding domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	6.9e-11	45.9
WP_096472201.1\|2408682_2409675_+	chemotaxis protein CheR	NA	NA	NA	NA
WP_096472202.1\|2409671_2410451_+	chemoreceptor glutamine deamidase CheD	NA	NA	NA	NA
WP_096472203.1\|2410447_2411539_+	chemotaxis response regulator protein-glutamate methylesterase	NA	NA	NA	NA
WP_034183905.1\|2411606_2412002_+	chemotaxis protein CheY	Q56AR1	Bacillus_thuringiensis_phage	2.7e-07	31.9

DBSCAN-SWA_176

2423577 : 2424996

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047899529.1\|2423577_2424996_+	adenosylhomocysteinase	S4VPF6	Pandoravirus	2.6e-44	30.3

DBSCAN-SWA_177

2436466 : 2439034

Agrobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_027788625.1\|2436466_2437126_-	exonuclease	A0A2L0UZL4	Agrobacterium_phage	4.8e-33	39.8
WP_096472221.1\|2437122_2437767_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_096473116.1\|2438422_2439034_+	septal ring lytic transglycosylase RlpA family protein	F5B3X9	Synechococcus_phage	9.5e-20	57.5

DBSCAN-SWA_178

2452235 : 2452934

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047899551.1\|2452235_2452934_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.9e-36	39.5

DBSCAN-SWA_179

2466723 : 2467410

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048248168.1\|2466723_2467410_-	orotate phosphoribosyltransferase	S4VS55	Pandoravirus	6.1e-15	27.2

DBSCAN-SWA_180

2492575 : 2493766

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011350666.1\|2492575_2493766_+	elongation factor Tu	A0A1V0SLW6	Klosneuvirus	4.0e-14	28.8

DBSCAN-SWA_181

2497763 : 2512994

Chrysochromulina_ericina_virus(20.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472255.1\|2497763_2501870_+	DNA-directed RNA polymerase subunit beta	A0A0N9R0J7	Chrysochromulina_ericina_virus	3.3e-23	27.3
WP_034183757.1\|2501891_2506139_+	DNA-directed RNA polymerase subunit beta'	A0A2I7QNZ7	Vibrio_phage	2.3e-72	28.0
WP_096472256.1\|2506439_2508287_+	DNA helicase RecQ	F2NZ48	Diadromus_pulchellus_ascovirus	3.8e-72	40.0
WP_006400662.1\|2508514_2508895_+	30S ribosomal protein S12	NA	NA	NA	NA
WP_006477195.1\|2509067_2509538_+	30S ribosomal protein S7	NA	NA	NA	NA
WP_096472257.1\|2509661_2511764_+	elongation factor G	E4ZFJ7	Streptococcus_phage	4.2e-59	27.8
WP_011350666.1\|2511803_2512994_+	elongation factor Tu	A0A1V0SLW6	Klosneuvirus	4.0e-14	28.8

DBSCAN-SWA_182

2552298 : 2554177

Planktothrix_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085042805.1\|2552298_2553384_+	sn-glycerol-3-phosphate import ATP-binding protein UgpC	G9BWD6	Planktothrix_phage	1.1e-21	35.1
WP_096472276.1\|2553412_2554177_+	glycerophosphodiester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	6.1e-08	25.0

DBSCAN-SWA_183

2576160 : 2576982

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014898316.1\|2576160_2576982_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.1e-21	29.4

DBSCAN-SWA_184

2580515 : 2581442

Cedratvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472290.1\|2580515_2581442_+	ABC transporter ATP-binding protein	A0A1M7XV31	Cedratvirus	2.6e-21	32.4

DBSCAN-SWA_185

2593398 : 2595583

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472298.1\|2593398_2594187_+	twin-arginine translocase subunit TatC	A0A1B1IVR7	uncultured_Mediterranean_phage	1.6e-27	31.0
WP_047899631.1\|2594377_2595583_-	Do family serine endopeptidase	A0A1B1IRD3	uncultured_Mediterranean_phage	1.9e-11	34.3

DBSCAN-SWA_186

2600129 : 2633199

uncultured_Caudovirales_phage(50.0%)

transposase,protease,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472303.1\|2600129_2600657_+\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	9.7e-21	52.0
WP_157776353.1\|2600835_2601171_+	hypothetical protein	NA	NA	NA	NA
WP_172902936.1\|2601157_2601709_+	hypothetical protein	NA	NA	NA	NA
WP_096472304.1\|2601809_2602544_-	response regulator transcription factor	NA	NA	NA	NA
WP_096472305.1\|2602545_2603631_-	histidine kinase	NA	NA	NA	NA
WP_096472306.1\|2604040_2604583_+	hypothetical protein	NA	NA	NA	NA
WP_047899640.1\|2604939_2605143_+	hypothetical protein	NA	NA	NA	NA
WP_096472307.1\|2605202_2606003_-	cystine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_096472308.1\|2606374_2609554_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	4.6e-57	28.4
WP_096472309.1\|2614197_2614473_+	hypothetical protein	NA	NA	NA	NA
WP_157776354.1\|2614504_2614639_-	hypothetical protein	NA	NA	NA	NA
WP_096472311.1\|2614753_2615889_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_096472312.1\|2616120_2616438_+	hypothetical protein	NA	NA	NA	NA
WP_096472313.1\|2616517_2617300_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_096472314.1\|2617296_2618643_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_096472315.1\|2618745_2619357_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_096472316.1\|2619731_2620376_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_027788514.1\|2620408_2620924_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_006477094.1\|2620939_2622430_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_006477093.1\|2622500_2623004_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_096472317.1\|2623066_2623552_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_096472318.1\|2623628_2625464_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_096472319.1\|2625427_2626528_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_096472320.1\|2626571_2629241_+	type VI secretion system ATPase TssH	A0A223W0B1	Agrobacterium_phage	5.0e-89	32.3
WP_096472321.1\|2629284_2630406_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_096472322.1\|2630520_2633199_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	2.6e-53	26.5

DBSCAN-SWA_187

2647311 : 2649480

Acinetobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472330.1\|2647311_2649480_-	peptidase M1	A0A0P0IY26	Acinetobacter_phage	2.4e-49	26.4

DBSCAN-SWA_188

2657981 : 2658185

Lake_Baikal_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006477070.1\|2657981_2658185_-	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	1.4e-20	71.6

DBSCAN-SWA_189

2663166 : 2671707

Pseudomonas_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472342.1\|2663166_2664249_-	peptide chain release factor 1	A0A0S4KWG0	Pseudomonas_phage	6.7e-08	46.6
WP_096472343.1\|2664331_2665630_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_096472344.1\|2665656_2666418_-	response regulator transcription factor	NA	NA	NA	NA
WP_027788489.1\|2666589_2666844_+	hypothetical protein	NA	NA	NA	NA
WP_096472345.1\|2666862_2668677_+	aminopeptidase P family protein	A0A0P0I8D7	Acinetobacter_phage	4.6e-171	50.3
WP_096472346.1\|2668732_2669284_+	cysteine hydrolase	NA	NA	NA	NA
WP_096472347.1\|2669280_2669904_+	HAD-IA family hydrolase	NA	NA	NA	NA
WP_096472348.1\|2670039_2671707_-	energy-dependent translational throttle protein EttA	A0A2K9L0W2	Tupanvirus	1.4e-41	27.3

DBSCAN-SWA_190

2677041 : 2678407

Bacillus_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472354.1\|2677041_2678407_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	3.1e-79	53.4

DBSCAN-SWA_191

2684630 : 2690127

Acinetobacter_phage(60.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472360.1\|2684630_2685530_-	uracil-DNA glycosylase	J9QYL4	Leporid_alphaherpesvirus	2.6e-50	49.3
WP_096472361.1\|2685543_2686170_-	CYTH domain-containing protein	NA	NA	NA	NA
WP_096472362.1\|2686169_2686955_-	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	8.4e-53	46.3
WP_047899695.1\|2686984_2688016_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	9.6e-81	46.7
WP_096472363.1\|2688029_2688620_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	5.3e-68	60.0
WP_034183729.1\|2688633_2690127_-	anthranilate synthase component I	A0A0B5J984	Pandoravirus	6.5e-38	30.3

DBSCAN-SWA_192

2706807 : 2710693

Escherichia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472370.1\|2706807_2708883_+	molybdopterin oxidoreductase family protein	A0A077SK27	Escherichia_phage	6.3e-47	25.4
WP_096472371.1\|2709019_2710693_+	long-chain fatty acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.4e-33	26.0

DBSCAN-SWA_193

2730881 : 2731391

Pelagibacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472381.1\|2730881_2731391_+	peroxiredoxin	M1I839	Pelagibacter_phage	4.3e-26	42.3

DBSCAN-SWA_194

2738432 : 2738876

Rhizoctonia_fumigata_mycovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047899728.1\|2738432_2738876_+	NUDIX domain-containing protein	A0A0B5CYJ3	Rhizoctonia_fumigata_mycovirus	2.3e-07	39.6

DBSCAN-SWA_195

2749058 : 2750177

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472388.1\|2749058_2750177_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	5.7e-63	42.7

DBSCAN-SWA_196

2758574 : 2763143

Pseudomonas_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472397.1\|2758574_2761568_+	ribonucleoside-diphosphate reductase subunit alpha	A0A2H4P767	Pseudomonas_phage	5.0e-170	44.1
WP_047899748.1\|2761931_2763143_+	ribonucleotide-diphosphate reductase subunit beta	A0A2P0VNY9	Tetraselmis_virus	5.7e-40	31.5

DBSCAN-SWA_197

2784158 : 2787615

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472412.1\|2784158_2784938_+	SDR family oxidoreductase	W8CYX9	Bacillus_phage	1.3e-08	37.8
WP_096472413.1\|2785040_2786036_+	arabinose ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_096472414.1\|2786103_2787615_+	L-arabinose ABC transporter ATP-binding protein AraG	W6JKT0	Anomala_cuprea_entomopoxvirus	1.9e-08	23.8

DBSCAN-SWA_198

2791645 : 2792146

Pseudomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472418.1\|2791645_2792146_-	CinA family protein	B5TK85	Pseudomonas_phage	3.2e-29	47.7

DBSCAN-SWA_199

2801008 : 2801425

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472426.1\|2801008_2801425_-	VOC family protein	A0A2K9L5C5	Tupanvirus	2.6e-13	34.4

DBSCAN-SWA_200

2809415 : 2813932

Paramecium_bursaria_Chlorella_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472432.1\|2809415_2810372_+	2-hydroxyacid dehydrogenase	M1HTA3	Paramecium_bursaria_Chlorella_virus	7.9e-13	26.0
WP_096472433.1\|2810382_2811441_+	L-idonate 5-dehydrogenase	NA	NA	NA	NA
WP_096472434.1\|2811528_2812728_-	MFS transporter	NA	NA	NA	NA
WP_096472435.1\|2813041_2813932_+	transcriptional regulator CynR	A0A2P0ZL89	Lactobacillus_phage	4.3e-13	25.2

DBSCAN-SWA_201

2821881 : 2827634

Staphylococcus_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472444.1\|2821881_2824476_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	6.8e-176	40.1
WP_034182717.1\|2824514_2825066_+	LPS-assembly family protein	NA	NA	NA	NA
WP_096472445.1\|2825084_2826179_+	DNA polymerase III subunit delta	NA	NA	NA	NA
WP_096472446.1\|2826362_2827634_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	5.1e-84	48.0

DBSCAN-SWA_202

2836688 : 2838077

Bodo_saltans_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472451.1\|2836688_2838077_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	1.0e-109	46.9

DBSCAN-SWA_203

2843432 : 2844158

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472457.1\|2843432_2844158_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.8e-31	39.4

DBSCAN-SWA_204

2857616 : 2857988

Lake_Baikal_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034182738.1\|2857616_2857988_+	iron-sulfur cluster insertion protein ErpA	A0A2H4N7M3	Lake_Baikal_phage	7.3e-31	57.8

DBSCAN-SWA_205

2864072 : 2868248

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472467.1\|2864072_2865143_-	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	7.0e-10	27.0
WP_096472468.1\|2865251_2865833_-	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_096472469.1\|2865988_2866531_-	crossover junction endodeoxyribonuclease RuvC	NA	NA	NA	NA
WP_096472470.1\|2866682_2868248_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	8.3e-68	47.7

DBSCAN-SWA_206

2895392 : 2903328

uncultured_Mediterranean_phage(75.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472491.1\|2895392_2896670_+	MFS transporter	Q6JIH2	Burkholderia_virus	6.1e-85	44.6
WP_172902939.1\|2896685_2898248_-	PDZ domain-containing protein	NA	NA	NA	NA
WP_034182770.1\|2898480_2899431_-	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	5.2e-41	34.2
WP_096472492.1\|2899449_2901471_-	protein translocase subunit SecD	NA	NA	NA	NA
WP_034182772.1\|2901577_2901901_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	2.3e-12	42.2
WP_096472493.1\|2902134_2903328_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	6.3e-84	45.5

DBSCAN-SWA_207

2907185 : 2908145

Lactobacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047899847.1\|2907185_2908145_+	hydrogen peroxide-inducible genes activator	A0A2P0ZL89	Lactobacillus_phage	3.1e-09	25.6

DBSCAN-SWA_208

2919327 : 2923890

Pandoravirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472502.1\|2919327_2920737_-	FAD-binding protein	A0A0B5JBT9	Pandoravirus	1.8e-08	29.4
WP_096472503.1\|2920874_2921426_+	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
WP_096472504.1\|2921520_2922729_+	NO-inducible flavohemoprotein	NA	NA	NA	NA
WP_096472505.1\|2922816_2923890_-	3-deoxy-7-phosphoheptulonate synthase AroG	A0A2I6UFP9	Klebsiella_phage	2.9e-80	48.8

DBSCAN-SWA_209

2941258 : 2953078

Chrysochromulina_ericina_virus(14.29%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472515.1\|2941258_2943205_+	molecular chaperone DnaK	A0A0N9QXN8	Chrysochromulina_ericina_virus	2.7e-145	49.5
WP_065500738.1\|2943470_2944607_+	molecular chaperone DnaJ	E3T4P7	Cafeteria_roenbergensis_virus	9.1e-24	39.5
WP_096472516.1\|2944611_2946531_+	bifunctional anthranilate synthase component I family protein/class IV aminotransferase	S4VT78	Pandoravirus	1.2e-57	37.1
WP_096472517.1\|2946684_2947500_-	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0N7HVJ8	Ostreococcus_lucimarinus_virus	2.0e-36	32.1
WP_096472518.1\|2947543_2948230_-	deoxynucleoside kinase	A0A0M3UL55	Enterococcus_phage	2.7e-07	25.9
WP_096472519.1\|2948226_2948769_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_096472520.1\|2948804_2950346_-	polynucleotide adenylyltransferase PcnB	H7BUW3	unidentified_phage	3.0e-22	30.6
WP_069746127.1\|2950351_2951029_-	HAD-IB family hydrolase	NA	NA	NA	NA
WP_096472521.1\|2951040_2951823_-	DnaA regulatory inactivator Hda	NA	NA	NA	NA
WP_096472522.1\|2952022_2953078_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SEW4	Cyanophage	9.8e-73	45.8

DBSCAN-SWA_210

2956489 : 2958475

Wolbachia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472527.1\|2956489_2958475_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	6.6e-78	33.1

DBSCAN-SWA_211

2962936 : 2967163

Staphylococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472533.1\|2962936_2963599_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	7.7e-07	24.8
WP_096473137.1\|2963673_2964768_+	chain-length determining protein	NA	NA	NA	NA
WP_172902940.1\|2964776_2965901_+	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SAG5	Catovirus	1.9e-26	29.2
WP_096472534.1\|2965897_2967163_+	UDP-N-acetyl-D-mannosamine dehydrogenase	M1HWZ1	Paramecium_bursaria_Chlorella_virus	7.8e-24	27.4

DBSCAN-SWA_212

2976744 : 2979461

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157776360.1\|2976744_2978133_+	BNR-4 repeat-containing protein	A0A0S2SXR0	Bacillus_phage	6.1e-30	36.1
WP_096472541.1\|2978291_2979461_+	nucleotide sugar dehydrogenase	A0A1J0FA55	Only_Syngen_Nebraska_virus	1.1e-112	53.7

DBSCAN-SWA_213

2983409 : 2984495

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472546.1\|2983409_2984495_+	glycosyltransferase	A0A1V0SAE6	Catovirus	5.6e-23	27.1

DBSCAN-SWA_214

2997995 : 3003503

Escherichia_phage(40.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472551.1\|2997995_2999324_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	D2TEZ5	Emiliania_huxleyi_virus	4.7e-48	34.0
WP_096472552.1\|2999320_2999995_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_096473140.1\|3000089_3000992_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	5.0e-25	31.7
WP_096472553.1\|3001000_3001552_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	4.2e-51	53.6
WP_096472554.1\|3001536_3002430_-	glucose-1-phosphate thymidylyltransferase RfbA	A0A291LA53	Escherichia_phage	9.8e-98	58.5
WP_096472555.1\|3002441_3003503_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	3.5e-86	47.6

DBSCAN-SWA_215

3019954 : 3021202

Aeromonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472563.1\|3019954_3021202_+	serine hydroxymethyltransferase	A0A219YCZ0	Aeromonas_phage	7.0e-94	50.9

DBSCAN-SWA_216

3040814 : 3041813

Only_Syngen_Nebraska_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472578.1\|3040814_3041813_-	2-hydroxyacid dehydrogenase	A0A1J0F959	Only_Syngen_Nebraska_virus	4.3e-62	43.6

DBSCAN-SWA_217

3044836 : 3053120

Acinetobacter_phage(75.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472581.1\|3044836_3045772_-	helix-turn-helix transcriptional regulator	A0A291LAM3	Bordetella_phage	2.2e-15	41.3
WP_096472582.1\|3045908_3046799_+	EamA family transporter	NA	NA	NA	NA
WP_096472583.1\|3046907_3048122_-	MFS transporter	NA	NA	NA	NA
WP_096472584.1\|3048469_3050014_+	xanthine dehydrogenase small subunit	A0A0P0IVM8	Acinetobacter_phage	6.4e-129	50.2
WP_096472585.1\|3050032_3052396_+	xanthine dehydrogenase molybdopterin binding subunit	A0A0P0I429	Acinetobacter_phage	8.3e-237	54.9
WP_096472586.1\|3052502_3053120_+	xanthine dehydrogenase accessory protein XdhC	A0A0P0IKN7	Acinetobacter_phage	1.6e-22	39.5

DBSCAN-SWA_218

3078814 : 3079864

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472605.1\|3078814_3079864_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.1e-20	33.6

DBSCAN-SWA_219

3087273 : 3089254

uncultured_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011544732.1\|3087273_3087567_+	co-chaperone GroES	A0A221S4A8	uncultured_virus	4.7e-17	40.4
WP_096472611.1\|3087613_3089254_+	chaperonin GroEL	A0A2I7SAK5	Vibrio_phage	1.4e-171	62.6

DBSCAN-SWA_220

3093930 : 3094962

Only_Syngen_Nebraska_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006476735.1\|3093930_3094962_+	aspartate carbamoyltransferase catalytic subunit	A0A1J0F9B8	Only_Syngen_Nebraska_virus	2.5e-28	33.7

DBSCAN-SWA_221

3098397 : 3108317

Enterobacteria_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472618.1\|3098397_3099459_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	2.1e-86	48.0
WP_096472619.1\|3099470_3100364_+	glucose-1-phosphate thymidylyltransferase RfbA	A0A291LA53	Escherichia_phage	1.3e-97	59.9
WP_096472620.1\|3100348_3100900_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	2.3e-49	53.6
WP_096472621.1\|3100892_3101795_+	dTDP-4-dehydrorhamnose reductase	I7HXC9	Enterobacteria_phage	1.0e-25	36.0
WP_096473151.1\|3101935_3103381_+	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	A0A1V0SH58	Hokovirus	3.9e-56	29.3
WP_096472622.1\|3103380_3104175_+	ABC transporter permease	NA	NA	NA	NA
WP_096472623.1\|3104174_3105395_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.8e-09	25.5
WP_096473152.1\|3105391_3106786_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_096472624.1\|3106880_3108317_+	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase	R9S8D5	Prochlorococcus_phage	7.0e-21	29.9

DBSCAN-SWA_222

3112424 : 3114354

Bathycoccus_sp._RCC1105_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472626.1\|3112424_3113459_+	GDP-mannose 4,6-dehydratase	E5EQW4	Bathycoccus_sp._RCC1105_virus	4.7e-104	55.2
WP_096472627.1\|3113436_3114354_+	GDP-mannose 4,6-dehydratase	M1HGM9	Acanthocystis_turfacea_Chlorella_virus	4.0e-14	26.3

DBSCAN-SWA_223

3126140 : 3127163

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472634.1\|3126140_3127163_-	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	6.4e-85	47.5

DBSCAN-SWA_224

3130686 : 3132081

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472638.1\|3130686_3132081_+	phosphomannomutase/phosphoglucomutase	A0A127AWJ1	Bacillus_phage	6.5e-56	31.1

DBSCAN-SWA_225

3141226 : 3142781

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472646.1\|3141226_3141919_-	urea ABC transporter ATP-binding subunit UrtE	A0A2H4PQG7	Staphylococcus_phage	8.9e-14	23.9
WP_096472647.1\|3141923_3142781_-	urea ABC transporter ATP-binding protein UrtD	A0A2R8FG22	Brazilian_cedratvirus	4.3e-10	24.1

DBSCAN-SWA_226

3147832 : 3148489

Streptomyces_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472652.1\|3147832_3148489_-	protein-L-isoaspartate O-methyltransferase	A0A1J0MC50	Streptomyces_phage	9.3e-13	37.5

DBSCAN-SWA_227

3167935 : 3170854

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472670.1\|3167935_3168802_+	hypothetical protein	S5M4R0	Bacillus_phage	1.5e-05	22.0
WP_096472671.1\|3168839_3170051_-	peptidase S8/S53 subtilisin kexin sedolisin	A0A1V0SLL0	Klosneuvirus	6.1e-18	30.4
WP_157776366.1\|3170111_3170414_-	hypothetical protein	NA	NA	NA	NA
WP_047900028.1\|3170467_3170854_+	fluoride efflux transporter CrcB	A0A2H4J148	uncultured_Caudovirales_phage	2.9e-22	49.5

DBSCAN-SWA_228

3179564 : 3193062

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011351235.1\|3179564_3180083_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	6.2e-20	38.0
WP_096472678.1\|3180136_3181279_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.4e-48	36.5
WP_096472679.1\|3181472_3181991_-	DUF1993 domain-containing protein	NA	NA	NA	NA
WP_096472680.1\|3182263_3182866_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_096472681.1\|3182862_3183546_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_096472682.1\|3183648_3184278_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	6.1e-30	39.9
WP_096472683.1\|3184292_3185414_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2I2L4R9	Orpheovirus	2.0e-47	34.3
WP_048024194.1\|3185429_3186713_-	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_034182952.1\|3186901_3187354_-	hypothetical protein	NA	NA	NA	NA
WP_096472684.1\|3187600_3188818_+	Bcr/CflA family multidrug efflux MFS transporter	S4TR35	Salmonella_phage	3.6e-26	26.0
WP_096472685.1\|3188917_3190846_-	bifunctional transcriptional regulator/glucokinase	NA	NA	NA	NA
WP_096472686.1\|3190823_3191504_-	6-phosphogluconolactonase	NA	NA	NA	NA
WP_096472687.1\|3191592_3193062_-	glucose-6-phosphate dehydrogenase	H6WFS4	Cyanophage	3.0e-75	35.0

DBSCAN-SWA_229

3196766 : 3209744

Bacillus_virus(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047900051.1\|3196766_3197885_+	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	G9BWD6	Planktothrix_phage	4.0e-24	35.3
WP_034182961.1\|3197974_3198598_-	trimeric intracellular cation channel family protein	NA	NA	NA	NA
WP_096472689.1\|3198584_3199364_-	Smr/MutS family protein	NA	NA	NA	NA
WP_096472690.1\|3199500_3200463_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	6.0e-61	43.3
WP_096472691.1\|3200864_3203174_+	DNA translocase FtsK	G1FGP1	Mycobacterium_phage	1.4e-84	50.0
WP_096472692.1\|3203220_3203910_+	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_096472693.1\|3204107_3205418_+	replication-associated recombination protein A	G3MBE0	Bacillus_virus	2.5e-81	40.2
WP_072436110.1\|3205459_3205729_-	DUF2164 domain-containing protein	NA	NA	NA	NA
WP_096472694.1\|3205975_3207274_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	6.2e-93	50.4
WP_096472695.1\|3208208_3209744_+	HAMP domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	1.4e-11	39.1

DBSCAN-SWA_230

3225509 : 3228885

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472708.1\|3225509_3226193_+	guanylate kinase	A0A218KC48	Bacillus_phage	1.8e-14	33.5
WP_006025620.1\|3226251_3226455_+	DNA-directed RNA polymerase subunit omega	NA	NA	NA	NA
WP_047900076.1\|3226518_3228885_+	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A291L9W9	Bordetella_phage	3.4e-12	33.5

DBSCAN-SWA_231

3232511 : 3233983

Lake_Baikal_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011351289.1\|3232511_3232715_+	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	3.5e-19	72.7
WP_096472711.1\|3232855_3233983_+	DNA polymerase III subunit epsilon	I6R9X8	Croceibacter_phage	1.6e-12	41.9

DBSCAN-SWA_232

3242310 : 3243324

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472717.1\|3242310_3243324_-	class 1 fructose-bisphosphatase	A0A1V0SKX4	Klosneuvirus	7.0e-52	36.6

DBSCAN-SWA_233

3250969 : 3251974

Acinetobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047900094.1\|3250969_3251974_-	xanthine dehydrogenase accessory protein XdhC	A0A0P0IKN7	Acinetobacter_phage	5.7e-38	34.4

DBSCAN-SWA_234

3259007 : 3260303

Burkholderia_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472731.1\|3259007_3260303_+	MFS transporter	Q6JIH2	Burkholderia_virus	3.9e-63	36.9

DBSCAN-SWA_235

3281217 : 3285760

Bacillus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472747.1\|3281217_3283821_+	DNA gyrase subunit A	G3M9Z5	Bacillus_virus	1.0e-99	32.4
WP_021157463.1\|3283904_3284504_+	DUF2059 domain-containing protein	NA	NA	NA	NA
WP_096473160.1\|3284677_3285760_+	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	1.8e-85	46.3

DBSCAN-SWA_236

3291884 : 3303556

Bacillus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006486894.1\|3291884_3292208_+	integration host factor subunit beta	A7KV42	Bacillus_phage	2.1e-10	40.0
WP_012328123.1\|3292417_3292711_+	LapA family protein	NA	NA	NA	NA
WP_096472751.1\|3292764_3293937_+	lipopolysaccharide assembly protein LapB	NA	NA	NA	NA
WP_096472752.1\|3294027_3295428_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	8.8e-77	38.3
WP_096472753.1\|3295435_3296386_+	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	1.2e-16	27.1
WP_034183439.1\|3296449_3297442_+	ADP-glyceromanno-heptose 6-epimerase	R9S880	Prochlorococcus_phage	9.1e-28	31.2
WP_096472754.1\|3297515_3297860_+	helix-hairpin-helix domain-containing protein	NA	NA	NA	NA
WP_096472755.1\|3298074_3298977_+	cysteine synthase CysM	A0A1X9I5F1	Streptococcus_phage	6.3e-52	40.2
WP_096472756.1\|3299043_3300387_-	lytic murein transglycosylase B	NA	NA	NA	NA
WP_011351344.1\|3300430_3301354_+	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	5.1e-41	34.9
WP_096472757.1\|3301385_3302306_-	alpha/beta hydrolase	Q6TUZ7	Yaba_monkey_tumor_virus	1.1e-16	27.2
WP_096472758.1\|3302521_3303556_+	methionine ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	6.8e-26	33.2

DBSCAN-SWA_237

3320950 : 3328379

Diachasmimorpha_longicaudata_entomopoxvirus(33.33%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472772.1\|3320950_3321577_+	oligoribonuclease	Q8B5Y0	Diachasmimorpha_longicaudata_entomopoxvirus	2.2e-27	39.9
WP_096472773.1\|3321593_3322214_-	molybdopterin adenylyltransferase	NA	NA	NA	NA
WP_096472774.1\|3322194_3322809_-	ribosome-associated protein	NA	NA	NA	NA
WP_096472775.1\|3322927_3324298_+\|protease	metalloprotease PmbA	NA	NA	NA	NA
WP_096472776.1\|3324381_3324882_-	dihydrofolate reductase	A0A0A0PL85	Bacillus_phage	3.6e-25	43.2
WP_096472777.1\|3325132_3325468_-	hypothetical protein	NA	NA	NA	NA
WP_096472778.1\|3325968_3327366_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_096473161.1\|3327407_3328379_+	thymidylate synthase	Q5QC60	Escherichia_phage	5.4e-49	38.2

DBSCAN-SWA_238

3341795 : 3346290

Agrobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472788.1\|3341795_3342995_+	nicotinate phosphoribosyltransferase	A0A2L0UZQ6	Agrobacterium_phage	5.0e-57	35.0
WP_096472789.1\|3343082_3343745_+	lactate utilization protein C	NA	NA	NA	NA
WP_096472790.1\|3343788_3345219_+	sodium:proton antiporter	NA	NA	NA	NA
WP_096473164.1\|3345300_3346290_+	D-glycerate dehydrogenase	M1HST2	Paramecium_bursaria_Chlorella_virus	1.7e-13	23.3

DBSCAN-SWA_239

3364728 : 3376143

Trichoplusia_ni_ascovirus(16.67%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_034183095.1\|3364728_3365478_+	3-oxoacyl-ACP reductase FabG	Q06VL0	Trichoplusia_ni_ascovirus	2.9e-18	34.0
WP_004197638.1\|3365622_3365862_+	acyl carrier protein	B2ZXV3	Ralstonia_phage	1.6e-10	47.1
WP_096472803.1\|3366026_3367259_+	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_096472804.1\|3367271_3367736_+	hypothetical protein	NA	NA	NA	NA
WP_034183098.1\|3367827_3368427_+	RNA polymerase sigma factor RpoE	A0A0F6TH34	Sinorhizobium_phage	3.8e-05	27.7
WP_096472805.1\|3368513_3369131_+	sigma-E factor negative regulatory protein	NA	NA	NA	NA
WP_065500454.1\|3369136_3370189_+	MucB/RseB C-terminal domain-containing protein	NA	NA	NA	NA
WP_096472806.1\|3370205_3371702_+\|protease	DegQ family serine endoprotease	A0A1B1IT49	uncultured_Mediterranean_phage	1.5e-21	29.3
WP_096472807.1\|3371709_3371979_+	glutaredoxin family protein	NA	NA	NA	NA
WP_096472808.1\|3372059_3373853_+	elongation factor 4	E4ZFJ7	Streptococcus_phage	1.3e-21	24.4
WP_096472809.1\|3373869_3374763_+	signal peptidase I	NA	NA	NA	NA
WP_096472810.1\|3374916_3376143_+	ribonuclease III	G8DDA3	Micromonas_pusilla_virus	9.5e-19	30.7

DBSCAN-SWA_240

3397736 : 3399569

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472830.1\|3397736_3399569_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.2e-38	27.3

DBSCAN-SWA_241

3420355 : 3424156

Burkholderia_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472842.1\|3420355_3421150_+	ABC transporter ATP-binding protein	M1H3A1	Paramecium_bursaria_Chlorella_virus	2.4e-07	25.0
WP_096472843.1\|3421172_3422216_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_096472845.1\|3422965_3423583_-	hypothetical protein	R4JJZ3	Burkholderia_phage	7.5e-57	56.1
WP_096473166.1\|3423586_3424156_-	PAAR domain-containing protein	R4JMI1	Burkholderia_phage	2.2e-66	63.2

DBSCAN-SWA_242

3438424 : 3439897

Tetraselmis_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472856.1\|3438424_3439897_+	NYN domain-containing protein	A0A2P0VNQ4	Tetraselmis_virus	3.8e-06	33.0

DBSCAN-SWA_243

3477508 : 3479480

Escherichia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047900250.1\|3477508_3478138_-	lytic transglycosylase domain-containing protein	I6ZXX9	Escherichia_phage	9.5e-15	33.6
WP_096473169.1\|3478694_3479480_+	response regulator transcription factor	Q6XM27	Feldmannia_irregularis_virus	1.0e-05	33.6

DBSCAN-SWA_244

3499647 : 3500421

Anomala_cuprea_entomopoxvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472891.1\|3499647_3500421_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	3.4e-14	27.5

DBSCAN-SWA_245

3511174 : 3517191

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472897.1\|3511174_3514885_+	exodeoxyribonuclease V subunit beta	A0A068EQC7	Bacillus_phage	4.6e-08	29.5
WP_096472898.1\|3514881_3517191_+	AAA family ATPase	A0A1P8DII4	Virus_Rctr197k	4.7e-03	45.8

DBSCAN-SWA_246

3525795 : 3526077

Pseudomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048251311.1\|3525795_3526077_-	XRE family transcriptional regulator	A0A2D1GR59	Pseudomonas_phage	1.8e-13	48.3

DBSCAN-SWA_247

3530420 : 3531452

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047900288.1\|3530420_3531452_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.2e-22	30.7

DBSCAN-SWA_248

3539685 : 3540711

Acanthamoeba_polyphaga_mimivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096473173.1\|3539685_3540711_+	alcohol dehydrogenase catalytic domain-containing protein	A0A2L2DIY2	Acanthamoeba_polyphaga_mimivirus	1.5e-25	27.1

DBSCAN-SWA_249

3544806 : 3546198

Erysipelothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472918.1\|3544806_3546198_+	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	3.8e-40	26.0

DBSCAN-SWA_250

3549302 : 3549977

Burkholderia_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472922.1\|3549302_3549977_+	SOS response-associated peptidase family protein	Q8W6R8	Burkholderia_virus	3.6e-76	57.9

DBSCAN-SWA_251

3554155 : 3557817

Burkholderia_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472927.1\|3554155_3555466_+	MHS family MFS transporter	Q6JIH2	Burkholderia_virus	1.1e-41	31.0
WP_096472928.1\|3555497_3556769_+	Zn-dependent hydrolase	NA	NA	NA	NA
WP_096472929.1\|3556794_3557817_+	histone deacetylase family protein	A0A0N9QAS6	Chrysochromulina_ericina_virus	1.3e-16	25.9

DBSCAN-SWA_252

3564546 : 3565302

Moraxella_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472934.1\|3564546_3565302_+	TerC family protein	A0A0R6PEZ3	Moraxella_phage	6.2e-37	39.6

DBSCAN-SWA_253

3580825 : 3590687

Burkholderia_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472953.1\|3580825_3582313_-	glycine betaine/L-proline transporter ProP	Q6JIH2	Burkholderia_virus	6.1e-60	32.5
WP_096472954.1\|3582853_3583186_+	YnfA family protein	A0A218MNG8	uncultured_virus	2.2e-26	56.2
WP_096472955.1\|3583213_3583948_-	DNA polymerase III subunit epsilon	A0A1X9SH08	Bradyrhizobium_phage	1.1e-38	40.3
WP_011351593.1\|3583986_3584430_-	ribonuclease HI	J9Q745	Salmonella_phage	2.4e-44	57.8
WP_096472956.1\|3584426_3585239_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_096472957.1\|3585257_3586064_+	hydroxyacylglutathione hydrolase	NA	NA	NA	NA
WP_096472958.1\|3586215_3587790_+	transglycosylase SLT domain-containing protein	U5PVY0	Bacillus_phage	1.1e-06	35.5
WP_096472959.1\|3587947_3589165_+	MFS transporter	NA	NA	NA	NA
WP_096472960.1\|3589541_3590687_+	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	3.5e-47	34.3

DBSCAN-SWA_254

3597354 : 3608765

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472966.1\|3597354_3599253_+	ATP-dependent metallopeptidase FtsH/Yme1/Tma family protein	C7U047	Ostreococcus_tauri_virus	4.3e-111	40.8
WP_096472967.1\|3599281_3600223_+	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	2.2e-23	33.6
WP_096472968.1\|3600251_3601607_+	phosphoglucosamine mutase	NA	NA	NA	NA
WP_096472969.1\|3602061_3603096_+	phosphate ABC transporter substrate-binding protein PstS	A0A1D7SRJ6	Cyanophage	1.9e-44	36.2
WP_096472970.1\|3603190_3604177_+	phosphate ABC transporter permease PstC	NA	NA	NA	NA
WP_096472971.1\|3604173_3605067_+	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_006490515.1\|3605082_3605931_+	phosphate ABC transporter ATP-binding protein PstB	W8CYL7	Bacillus_phage	9.5e-18	33.5
WP_034183285.1\|3605949_3606654_+	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_027787869.1\|3606686_3607388_+	phosphate regulon transcriptional regulator PhoB	W8CYM9	Bacillus_phage	2.3e-33	37.3
WP_096472972.1\|3607445_3608765_+	phosphate regulon sensor histidine kinase PhoR	W8CYF6	Bacillus_phage	7.8e-35	36.0

DBSCAN-SWA_255

3617727 : 3619347

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096472981.1\|3617727_3619347_-	AMP-binding protein	A0A2H4PQU7	Staphylococcus_phage	1.2e-64	34.5

Anti-CRISPR protein detection

Acr_ID: NZ_AP018111.1|WP_096472152.1|2336254_2338819_+|heavy-metal-translocating-P-type-ATPase

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_AP018111.1|WP_096472152.1|2336254_2338819_+|heavy-metal-translocating-P-type-ATPase

2336254_2338819_+

854 aa aa

2336254-2338819

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location
NZ_AP018111_5	Orphan	5.3\|2336543\|18\|NZ_AP018111\|CRISPRCasFinder	2336543-2336560	18	2336573-2336590
NZ_AP018111_5	Orphan	5.3\|2336543\|18\|NZ_AP018111\|CRISPRCasFinder	2336543-2336560	18	2336579-2336596
NZ_AP018111_5	Orphan	5.3\|2336543\|18\|NZ_AP018111\|CRISPRCasFinder	2336543-2336560	18	2336585-2336602

1. spacer 5.3|2336543|18|NZ_AP018111|CRISPRCasFinder matches to NZ_AP018111 position: 2336573-2336590, mismatch: 0

cacgaccacgaccacgac	CRISPR spacer
cacgaccacgaccacgac	Protospacer
******************

2. spacer 5.3|2336543|18|NZ_AP018111|CRISPRCasFinder matches to NZ_AP018111 position: 2336579-2336596, mismatch: 0

cacgaccacgaccacgac	CRISPR spacer
cacgaccacgaccacgac	Protospacer
******************

3. spacer 5.3|2336543|18|NZ_AP018111|CRISPRCasFinder matches to NZ_AP018111 position: 2336585-2336602, mismatch: 0

cacgaccacgaccacgac	CRISPR spacer
cacgaccacgaccacgac	Protospacer
******************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_AP018112

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_AP018111

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information