CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_AP017298	Staphylococcus capitis strain TW2795 plasmid ptw2795, complete sequence	0 crisprs	NA	0	0	0	0
NZ_AP014956	Staphylococcus capitis strain TW2795	2 crisprs	csa3,DEDDh,cas3,DinG	0	0	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_AP014956_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP014956_1

207609-207710

Orphan

Consensus_repeat	Method
GTCAAATTCAATCAGTGAGAGTAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP014956_1

>merge|NZ_AP014956|1|207609-207710|CRISPRCasFinder
GTCAAATTCAATCAGTGAGAGTAAATCAAAAAGTACAAGTATTGCAGATTCGCAAAGTAAATCAGCAGCTGAAAGTACGTCAAAATCAATCAGTGAGAGTAA

>NZ_AP014956|1|1|207609-207710|CRISPRCasFinder
GTCAAATTCAATCAGTGAGAGTAA	ATCAAAAAGTACAAGTATTGCAGATTCGCAAAGTAAATCAGCAGCTGAAAGTAC
GTCAAAATCAATCAGTGAGAGTAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014956.1\|WP_030062705.1\|203125_204454_+\|membrane-protein	unknown	unknown	unknown
NZ_AP014956.1\|WP_030058897.1\|199554_200328_+\|phosphonate-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|131368
NZ_AP014956.1\|WP_030058899.1\|202134_202785_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
NZ_AP014956.1\|WP_030062702.1\|214180_215740_+\|accessory-Sec-system-protein-Asp2	unknown	unknown	gnl\|CDD\|274739
NZ_AP014956.1\|WP_002434989.1\|201132_201942_+\|phosphonate-ABC-transporter,-permease-protein-PhnE	unknown	unknown	gnl\|CDD\|273441
NZ_AP014956.1\|WP_030058887.1\|191722_192367_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014956.1\|WP_030062698.1\|220201_221539_+\|accessory-Sec-system-glycosylation-chaperone-GtfB	unknown	unknown	gnl\|CDD\|274351
NZ_AP014956.1\|WP_002436374.1\|221642_222002_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014956.1\|WP_030058893.1\|196675_198235_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378253
NZ_AP014956.1\|WP_095323985.1\|216291_218682_+\|accessory-Sec-system-translocase-SecA2	unknown	unknown	gnl\|CDD\|163426
NZ_AP014956.1\|WP_030058895.1\|198469_199435_+\|phosphate/phosphite/phosphonate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|225762
NZ_AP014956.1\|WP_030058891.1\|194971_196507_-\|bifunctional-metallophosphatase/5'-nucleotidase	unknown	unknown	gnl\|CDD\|223808
NZ_AP014956.1\|WP_030062701.1\|215726_216299_+\|accessory-Sec-system-protein-Asp3	unknown	unknown	gnl\|CDD\|163423
NZ_AP014956.1\|WP_030062697.1\|222109_222457_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|273478
NZ_AP014956.1\|WP_030058889.1\|194581_194959_-\|DUF1801-domain-containing-protein	unknown	unknown	gnl\|CDD\|227933
NZ_AP014956.1\|WP_002435050.1\|200329_201136_+\|phosphonate-ABC-transporter,-permease-protein-PhnE	unknown	unknown	gnl\|CDD\|273441
NZ_AP014956.1\|WP_030062703.1\|212628_214197_+\|accessory-Sec-system-protein-Asp1	unknown	unknown	gnl\|CDD\|274740
NZ_AP014956.1\|WP_002454198.1\|222873_223221_+\|DUF4064-domain-containing-protein	unknown	unknown	unknown
NZ_AP014956.1\|WP_030062699.1\|218700_220209_+\|accessory-Sec-system-glycosyltransferase-GtfA	unknown	unknown	gnl\|CDD\|131964
NZ_AP014956.1\|WP_023350957.1\|211418_212618_+\|accessory-Sec-system-protein-translocase-subunit-SecY2	unknown	unknown	gnl\|CDD\|237095

Protein	Function_ID	Function_description	E-value
NZ_AP014956.1\|WP_002434989.1\|201132_201942_+\|phosphonate-ABC-transporter,-permease-protein-PhnE	gnl\|CDD\|273441	TIGR01097, PhnE, phosphonate ABC transporter, permease protein PhnE. Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions].	3.26291e-81
NZ_AP014956.1\|WP_030058897.1\|199554_200328_+\|phosphonate-ABC-transporter-ATP-binding-protein	gnl\|CDD\|131368	TIGR02315, Phosphonates_import_ATP-binding_protein_PhnC, phosphonate ABC transporter, ATP-binding protein. Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions].	9.83787e-146
NZ_AP014956.1\|WP_030058899.1\|202134_202785_+\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.59304e-50
NZ_AP014956.1\|WP_030062702.1\|214180_215740_+\|accessory-Sec-system-protein-Asp2	gnl\|CDD\|274739	TIGR03712, acc_sec_asp2, accessory Sec system protein Asp2. This protein is designated Asp2 because, along with SecY2, SecA2, and other proteins it is part of the accessory secretory protein system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	0
NZ_AP014956.1\|WP_030058893.1\|196675_198235_-\|hypothetical-protein	gnl\|CDD\|378253	pfam09822, ABC_transp_aux, ABC-type uncharacterized transport system. This domain is found in various eukaryotic and prokaryotic intra-flagellar transport proteins involved in gliding motility, as well as in several hypothetical proteins.	0.000179593
NZ_AP014956.1\|WP_030062698.1\|220201_221539_+\|accessory-Sec-system-glycosylation-chaperone-GtfB	gnl\|CDD\|274351	TIGR02919, conserved_hypothetical_protein, accessory Sec system glycosyltransferase GtfB. Members of this protein family are found only in Gram-positive bacteria of the Firmicutes lineage, including several species of Staphylococcus, Streptococcus, and Lactobacillus. [Protein fate, Protein modification and repair].	0
NZ_AP014956.1\|WP_030062697.1\|222109_222457_-\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|273478	TIGR01167, Zinc_metalloprotease_ZmpB, LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other].	0.00435382
NZ_AP014956.1\|WP_095323985.1\|216291_218682_+\|accessory-Sec-system-translocase-SecA2	gnl\|CDD\|163426	TIGR03714, Protein_translocase_subunit_SecA_2, accessory Sec system translocase SecA2. Members of this protein family are homologous to SecA and part of the accessory Sec system. This system, including both five core proteins for export and a variable number of proteins for glycosylation, operates in certain Gram-positive pathogens for the maturation and delivery of serine-rich glycoproteins such as the cell surface glycoprotein GspB in Streptococcus gordonii. [Protein fate, Protein and peptide secretion and trafficking].	0
NZ_AP014956.1\|WP_030058895.1\|198469_199435_+\|phosphate/phosphite/phosphonate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|225762	COG3221, PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component [Inorganic ion transport and metabolism].	6.18702e-93
NZ_AP014956.1\|WP_030058891.1\|194971_196507_-\|bifunctional-metallophosphatase/5'-nucleotidase	gnl\|CDD\|223808	COG0737, UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism].	7.78369e-93
NZ_AP014956.1\|WP_030062701.1\|215726_216299_+\|accessory-Sec-system-protein-Asp3	gnl\|CDD\|163423	TIGR03711, acc_sec_asp3, accessory Sec system protein Asp3. This protein is designated Asp3 because, along with SecY2, SecA2, and other proteins it is part of the accessory Sec system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	1.44213e-48
NZ_AP014956.1\|WP_030058889.1\|194581_194959_-\|DUF1801-domain-containing-protein	gnl\|CDD\|227933	COG5646, COG5646, Uncharacterized conserved protein [Function unknown].	2.00263e-27
NZ_AP014956.1\|WP_002435050.1\|200329_201136_+\|phosphonate-ABC-transporter,-permease-protein-PhnE	gnl\|CDD\|273441	TIGR01097, PhnE, phosphonate ABC transporter, permease protein PhnE. Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions].	3.73653e-99
NZ_AP014956.1\|WP_030062703.1\|212628_214197_+\|accessory-Sec-system-protein-Asp1	gnl\|CDD\|274740	TIGR03713, acc_sec_asp1, accessory Sec system protein Asp1. This protein is designated Asp1 because, along with SecY2, SecA2, and other proteins it is part of the accessory secretory protein system. The system is involved in the export of serine-rich glycoproteins important for virulence in a number of Gram-positive species, including Streptococcus gordonii and Staphylococcus aureus. This protein family is assigned to transport rather than glycosylation function, but the specific molecular role is unknown. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	0
NZ_AP014956.1\|WP_030062699.1\|218700_220209_+\|accessory-Sec-system-glycosyltransferase-GtfA	gnl\|CDD\|131964	TIGR02918, lipopolysaccharide_biosynthesis_protein, accessory Sec system glycosylation protein GtfA. Members of this protein family are found only in Gram-positive bacteria of the Firmicutes lineage, including several species of Staphylococcus, Streptococcus, and Lactobacillus. Members are associated with glycosylation of serine-rich glycoproteins exported by the accessory Sec system. [Protein fate, Protein modification and repair].	0
NZ_AP014956.1\|WP_023350957.1\|211418_212618_+\|accessory-Sec-system-protein-translocase-subunit-SecY2	gnl\|CDD\|237095	PRK12417, secY, preprotein translocase subunit SecY; Reviewed.	5.90734e-157

>NZ_AP014956.1|WP_030062705.1|203125_204454_+|membrane-protein
MKRFLKIHKHTLRENTLISLIFIMSLYNKWLLLLAIILSVLLLKRGILGVIQLIYLYTTRNLMISFFDTSDSAYDLTYAIYILIYVIGIFFLIRHIKRWVRSYLIFTFALASITLMLIYIIMSLITSNDPLYSITKLINYFIPLIIIVTLVYLIKEVDELIKWLANQVVTFILFTLIPLVMSLIKVLSQEQSFKGFFNDSNTFAVFLILGLLTLIISSMKYHKFNFFVMFVMMSGIFELYVTHSKLAWFVFIVCLFLSLLLLILKKRYKYLTIPLIISIIILSIFQPSIHYLIKSFVLNGNSVKSVLMPKDNQIKNIENVLETHMLMGNGFGMSLHGLTKNSDIVAGNMVFELMMFTGVIGLTCYVIYVLKVMLLATYMFKLTFVLFIATLLTNTIEIVMFNAINIGALCYILWGIYLKDGLHKDSKNKMVKKSLEVDKRNI
>NZ_AP014956.1|WP_030058899.1|202134_202785_+|SDR-family-oxidoreductase
MSVLVIGSNGAVGRKVISQLKDTEHSSVALVRKEEQVSDLKELGADKVVVQDLEEDFSSAFEGVDSVIFTAGSGGSTGADKTLLVDLWGAKKAVDYATKHQVKKFVHLSATDSVEPDKETDVMKPYAVAKHFSDLYIENSNLNYTIVHPGPLQNEEGTGKIDAELDIARDPNSYTIPREDVATVLIEALDASAVEGKDIFIQTGQTDIKDAINNIK
>NZ_AP014956.1|WP_002434989.1|201132_201942_+|phosphonate-ABC-transporter,-permease-protein-PhnE
MNEQKYKLNSKRYRERIIKNWIIAVIVAAIIIWAFAGMPALELKSKSIEILKSIFKGLFHPDLGYIYIPAGEDLLRGLLETFAIAVIGTFIASIICIPFAFLGARNMVKLRPVTGISKFILSIIRVFPEIVMALIFIKAVGPGSFSGVLALGIHSVGMLGKLFVEDIESLDFSAVESLKASGANKTKTLIFAVIPQILPSFISLILYRFELNLRSASILGLIGAGGIGTPLIFALQTRSWDRVGIILIGLVIMVAIVDLISGAIRKRIV
>NZ_AP014956.1|WP_002435050.1|200329_201136_+|phosphonate-ABC-transporter,-permease-protein-PhnE
MATPTSSTSKYDQYLNKKMSIKTSFTIILIAALIIWSFIYTGFSIGDLMIGIPQIGAFFGQMVPPDWSYLDQITKPMLDTIRMAIVGTFLGSIVSIPVALLCASNIVQTKWIAIPARFILNIVRTIPDLLLAAVFVAVFGIGQIPGVLALFILTICIIGKLLYESLETIEPGPMEAMTAVGANKVKWIVFGVVPQAISSFMSYVLFAFEINIRASAVLGLVGAGGIGLFYDQTLGLFQYKKTAMIILFTLLIVVIIDFVSSKVREKLA
>NZ_AP014956.1|WP_030058897.1|199554_200328_+|phosphonate-ABC-transporter-ATP-binding-protein
MSQIEFKDVNKVYPNGHVGLKNINLNIEKGDFAVIVGLSGAGKSTLLRSVNRLHDISSGDITIDGQSITKARGKQLLEMRRNIGMIFQHFNLVKRSTVLRNVLSGRVGYHPTWKMVLGLFPKEDKIKAINALERVNILDKYDQRSDQLSGGQQQRISIARALCQESAIILADEPVASLDPLTTKQVMDDLKKINEELGITILINLHFVDLAKEYGSRIIGLRAGELVYDGPASEADDDVFNHIYGRSINEDEKLGVE
>NZ_AP014956.1|WP_030058895.1|198469_199435_+|phosphate/phosphite/phosphonate-ABC-transporter-substrate-binding-protein
MKNLKFLVVLVLSVVIFAAACGNSSSLDNNKKSSDSGSDSGSSSGDYKPKELTVQFVPSQNADKLEAKAKPLEKLLSDKLGIPVKVSVSTNYNTIVEAMKSKKVDVGFLPPTAYTLAHDQKAADLLLQAQRYGVNKDGSSNKKLVDDYKSEILVKKNSGIKSLKDLKGKKIALQDVTSTAGYTFPLATLKKETGINATKDMKIVNVKGHDQAVISLLNGDVDAAAVFQDARTIVKKDQPNVFKDTKILKLTESIPNDTISVRPDMDKKFQEKLKKAFKDIAKSKKGHKIISEVYSHEGYTDTKDSNFDIVRKYEKEVQDMK
>NZ_AP014956.1|WP_030058893.1|196675_198235_-|hypothetical-protein
MKLFKVLSSTVLATAISVTTIQSAHATTQSTSSSSGQSDQTVLFDNSHAQTAGAADWVTDGAFSDYADSMKNKGYNVKELDGEANISNETLKNAHILVIPEANNPFKEKEQQAIVNFVKRGGSVIFISDHYNADRNLNRIDSSESMNGYRRGAYQDMTKDMNSGEKNSKAMQGVKSSDWLSNQFGVRFRYNALGDLNTQNIVSSKESFGITKDVKSVSMHSGSTLAITDPDKAKGIVYMPENLSNKQKWSHAVDQGIYSGGGTKEGPYIAISKVGKGKAAFIGDTSLVEDSSPKYQREDNGKSKKTYDGFKEQDNGTLLKNLTTWLGKSDSHESMKDTGVKIDNKTPLLNFEKPENSTEPQHEPWSQPEKGYKWYDRSTFKPGSYGSSQSGSDNNDESSSNDNSNSHHDQTGNAEFNLPQSIQPNHPFKVTVKLKGYDANSTINNLTVGIYKDGGKQIGSFSSDGSQFSQPGYSKDQTVKTDSNGEATLTLTAKVSEDINGAHIRLKQGKKVVTTTDIH
>NZ_AP014956.1|WP_030058891.1|194971_196507_-|bifunctional-metallophosphatase/5'-nucleotidase
MTQLAFYVVSDVHGFIFPTDFSHRDVELPMGLLKANHIIEQDCSHYDGSIKIDNGDFLQGSPLCNYLVSELATSRPLTDIYNRLNFNFGTIGNHEFNYGLKYLKQTIHQLDYPMLCANILENGEPFTGQGITYIKSQGLTIGVIGLTTQFIPHWEQPEYIETLTFQSAVETLSSQLPELRKQSDVVVVSYHGGFERDLETGEPTEALTGENEASEILRLFSDDIDVLITGHQHRDIATIYNQTAVIQPGTRGTKVGKIVLNIEHDNDVQIENCHLLDVEDCSSFEINQQDQNLRVHLEDWLDKKVATLPTSMRVENAFDARVKPHPFINLLNYILLESSGADITCTALFDSAKGFDKDVTMRDIINNYPFPNTFKVIELTGRDIKLAIERSAAYFDLHDEEISVSADFLEPKPQHFNYDIFAGIDYTIHVGRALGERVSDLFVNGKPLDEHKSYTICVNNYRAVGGGNYNMYENKPIIKDIQIEGAQLLINYLSTNDLSHIPKVVNFKVVK
>NZ_AP014956.1|WP_030058889.1|194581_194959_-|DUF1801-domain-containing-protein
MSEFNLFINDIENEAHREKLRHLFEWIETQYSDLTPVVKWNQPMYTYNETFIIAFSKAKQHFSIMPEAACLKQFKQRVTNAGYTQTENLFRIKWNHEIDYDLIGDMIKLNMEEKKDYTKFWRDHK
>NZ_AP014956.1|WP_030058887.1|191722_192367_+|hypothetical-protein
MKKVTLLSSAVLAGTIALSGVTGVANASDYHHGNFATYKEKVESLKKLKKDGAISNKEYKGKMEALKEFDKQGRTNMGSRPYGGMPPKGMTSEQYSELEYNVGNANEMPNSVFNKRIDRETQKIADKYKTTIYAPQKTFKPHTQQTKQGDRPYGGVAPKGMTSAQYAELEKKVGNASQMSKKAFAKKVDQETQKIADKYKTTIYAPQKTFKPHK
>NZ_AP014956.1|WP_023350957.1|211418_212618_+|accessory-Sec-system-protein-translocase-subunit-SecY2
MLKEFEYKILYKRILFTCFILIIYILGSNISIVGNEAIKQHKDSFFKLAISNVGGDLNTLNIFSLGLGPWLSSMIIITLMNYKNEDKVKTQTRVERHFKERLLTLLLSTIQGFYIIHSFINKKAITDTNIFILLLVLITGTLFLVWLADQNTTYGIAGPMPIVLMSLVKSMFNSHFAKLNLNPILLVIIICSLALILFILLFIERSEYRLEYNDIMNISSKDTPTYLSWKLNPAGSITIMMSLSIFILENNIVNLIGRLAVDKDFETTIFSFSNPIGITIYLLMQIVLGYVLSRFLINTRRKSKEFLKNGNYFEGIYPGKHTTRFLSQKARRVCWSGSIIVAIVLAIPLYCSLLVPHLFEEIYFSIQLIVFVYIGINIAETLRAYLYFDGYKQILDKYW
>NZ_AP014956.1|WP_030062703.1|212628_214197_+|accessory-Sec-system-protein-Asp1
MKRFIPAWYSHDKWWESTSVPFYQKRQYTDFDDMISLMTMHSKNNVDYQLMILSFSPYLRTFLHRYDLFETNYWSVFDDIQGVSHQTPQAIDYRDLAWPENTEFIFTPYQIQAVTGEHTFSKIHFSQEGYLMWIEDFQHNIIQRRYVIDDRGFISAVRTYTETGQSKMKHYFSIKGEEIFKEDLRNKTVTIKEQFQSNFKQTTYATMADLIEEKFKEYAEREIKKDDLIIVASDERHNSVMAHTIDESSLCFSVFTERNKKVTPELFDSISQARYCLVDTQDNQREIQRYAKESQTHLHLLRVTPFDAQTISNKSSQLYDTYVGLWIDQLPKHELRVILTSLFQYIQQKDHFKLKLLTKYKNDPNDWLMEEIARLNDTYHQEKQEHSDEIEDILASQIKKETVIELEYVPFSEDFVRAISNLRLVVDLSNEPDLFLQICCIGAGVPQVNYRGTDYVKHEQNGLIIKDISQIVSALDYFLVHLKKWNYSYAYSMRLVDEFSSINIIHQINQLFEGDDKYATYI
>NZ_AP014956.1|WP_030062702.1|214180_215740_+|accessory-Sec-system-protein-Asp2
MPRTFKVLQIGGNDLENLFENKREVEWDYIDTAVFDFESGYLQAVEALIEQNGAFDFVFTQAPYSESLINLFKIVSTPYNTVIDEAYWDVHFQEEKVVQQNFIKPLKYDNEEDLHQKLQAITFPGQYGDKVTPIHCRVNTAFIGKYQFNGNESLEISGNFGDQLTPLVTWSRNIIADENKVNQIWPEFKIEGEVKIQYTLRMIPVYSTEQPVETFIFEQNELDQPIELPARPYKANVSISLKAQGEGTLFVGSIHKRWSRLELGQFILGGQRFSDKNRNEFFHYFNPGDFKPPLNVYFSGYRTAEGFEGFFMMNRLNAPFILISDPRIEGGAFYLGSEDYENGIKDVILGALDYLGFTHDQLILSGLSMGSFGALYYATRLQPAAVIVGKPLINVGTIANNMKLVRPNDFGTSLDVLRSNEGGISENEINQLDQKFWNQIHNSQLTQTTFAIAYMEHDDYDINAFHELLPVLTKQYARVMSRSVPGRHNDDSSTITNWFINFYHLIMAQQFGRESHARS
>NZ_AP014956.1|WP_030062701.1|215726_216299_+|accessory-Sec-system-protein-Asp3
MQEAKQFEVKWRLVNLTTFMYGTKLHFNNDDIYFENPLMPSGTVIHNWYMLTNFTEDRVSPKLPILKKGHRYLFKFNFQVEPEGAAYFKIKFYRKNKEQFEYKIIKNKEEEIVYPLEAHSYQLELVNAGMDHLHFQNITIVELGDGTYRNPSTAKGINTKEKFEIMNRVIKNARTYDLDALSDAGGENRE
>NZ_AP014956.1|WP_095323985.1|216291_218682_+|accessory-Sec-system-translocase-SecA2
MNSGINTIINNMRLRRVSKSLKQINSLSKEYANYTDEQLKAKTLQFKERLQSSKTTLDKLLPEAYATVREASKRVLGMYPKDVQVLGAIVMHQGNIAEMQTGEGKTLTATMPLYLNGLAGKGAYLITTNEYLAKRDYQEMKPLYEWLGLSASLGFVDIPNYEYEENEKYHLYHHDIVYTTNGRLGFDYLIDNLADDIQAKFLPDLNFAIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKSFVETLEEDVHFQVKFNKKEVWLTEEGIEAANHYFKVNNMYENQHFDLVRIINLSLRAKYLFKYNLDYFIFDGEIVLIDRITGRMLQGTKLQSGLHQAIEAIEDVEISRDMSVMATITFQNLFKQFNQFSGMTGTGKLGEKEFFDLYSKIVVEIPTNSPIKRDDRPDRVFANGNIKNEAILKSVVDIHRTQQPVLLITRTAEAAEYFSQQLFKKDIPNNLLIAQNVAKEAQMIAEAGQLSAVTVATSMAGRGTDIKLAKDVFEIGGLAVIINEHMENSRVDRQLRGRSGRQGDPGYSQIFVSLDDYLVKRWSNSNLVGNEKLLSLESSKLENSTLFQRRVKSIVNKAQRVSEETAMVNREMANEFEKSISIQREKIYDLRDQILEREHFEDFNFEQLARDVFANDIKYKKLINEEALINYIYKNLSFVFNETVSNIDIKNREEVIQFLIKQFKQQLNHNLKEVSDPYLKRRFLQKSFIKAIDSEWIEQVDNLQQLKASVNNRQNGQRNIIYEYHKVALETYELMAKDIKRKIIRNLCLSILTFDKSDDMVIHFP
>NZ_AP014956.1|WP_030062699.1|218700_220209_+|accessory-Sec-system-glycosyltransferase-GtfA
MTIYNINFGIGWASSGVEYAQAYRAQLLRQLNYPIKFVFLDFIQSENIQTLTSNIGFKDDEIIWLYQYFTDINIAPTTYTVNDLISELGNEVSSYERNGKVLRLYLDNNETFVTCYLKNPEENYVDRAEFVVNGMLIRKDFYSYVRTFSEYYAPYDKRAKLYMRQFYNEDGSIVYKEYIDDDAHVYVFDDARLYSKEEFIAYFIRKLHLESDDIVIIDRATDVGQAILQNKGDSKVGVVVHAEHYSMNSTDDTHILWNNYYEYQFENAKYIDFFITATDLQNKILNEQFKNYTHDSPRIRTIPVGSLHQLSYPQEPRMPFSIITASRLASEKHVDWIALAVIKARKALPELTFDIYGHGPEQERIEKIIQEHHAQDYIRLKGHVNLQDVYRHYQLFVAASQSEGFGLTLMEAVGSGLGMIGFDVNYGSPTFIKDARNGYLIPINLDRESINDVTDHMATKIIQYFENGPSHPHDVSYEIAEEFKTTHIVEKWEQLIKEVLHD
>NZ_AP014956.1|WP_030062698.1|220201_221539_+|accessory-Sec-system-glycosylation-chaperone-GtfB
MINLFENYDSNTRELHESLKIAGYHPFTIVLNDDGFLPDEVTSPYQYFANYQIYDDDKPAFFNDVTTPPFWEIKGNGTMAQVIDMGELRGKIFYKEYYKTRVVSYVEWLDKHQRLRSVDYYTKEGFKYAEKVYDLSGTPILKKYMDRNGKEVIYENYVTQNIVLDYRGKSYFFETTKEFIAFYLNELNIDYKQVVINSLSTPFITLYHQSIAQQVVLFWQEQSQGHVPGNMKLMFEPNNFSQFSVIIPEREEYQMITNQLNSTENQFVYPSGYLYSKKKENQLSKNILILTNSDQIPHLEALIQRHDDFNFHIGAVTEMSTVLTSLEHYPNAKHYPTIKRDMVEELYQRCDIYLDINEGGEILNAVRTAFDYNLLILGYKETAHHLTITSPSHLFSAENVAELSRVLTEVGSNKDIFKDKLDQQSSHANEISVSTFKTALNQALN
>NZ_AP014956.1|WP_002436374.1|221642_222002_+|hypothetical-protein
MNNFDERYDERHNEKANNVLGALSYLSVFFAPVLFPLVVWIIAKPPGSTHSRNALFNHIFTWVFVAIGLLSLMIIPALFDSAHSGIGITIAFIVAAIFFIWAIVLFFTNIIRGIKLLII
>NZ_AP014956.1|WP_030062697.1|222109_222457_-|LPXTG-cell-wall-anchor-domain-containing-protein
MTQKFVACTIGSVLITLAFLVVCNQPVSAATPNENQTMNQLQLHSLKDDSKDASSEPYFFKSNAVEHKHPIYQTTSKSTLPETGKSISHSPVMAGIIALVLGLVILIHKKISARK
>NZ_AP014956.1|WP_002454198.1|222873_223221_+|DUF4064-domain-containing-protein
MNEMQKVKPTNRVAEMVLGIMGSIFGILGGLFAIMLQGVSSQLDTDGGNVGGLGVAVIITCIITLILSCIINKKRVLIGVLLIIGGILNFIFISFFGILSGILILVAGILALVRK

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Crispr_ID: NZ_AP014956_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP014956_2

2123758-2123847

Orphan

Consensus_repeat	Method
TTGGATTTTTAATCCTTAGTGTTGCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP014956_2

>merge|NZ_AP014956|2|2123758-2123847|CRISPRCasFinder
TTGGATTTTTAATCCTTAGTGTTGCTTATGCAATGGACTCTGTTCATTGTAATCCTCTATTCACTTGGATTTTTAATCCTTAGTGTTGCT

>NZ_AP014956|2|2|2123758-2123847|CRISPRCasFinder
TTGGATTTTTAATCCTTAGTGTTGCT	TATGCAATGGACTCTGTTCATTGTAATCCTCTATTCAC
TTGGATTTTTAATCCTTAGTGTTGCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014956.1\|WP_030059138.1\|2127276_2127714_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014956.1\|WP_030059140.1\|2127771_2128227_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_AP014956.1\|WP_002433193.1\|2117328_2117613_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014956.1\|WP_002433221.1\|2112601_2112880_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014956.1\|WP_023350700.1\|2128370_2129060_+\|DUF1129-family-protein	unknown	unknown	gnl\|CDD\|368981
NZ_AP014956.1\|WP_030059118.1\|2112970_2114344_-\|deoxyribodipyrimidine-photo-lyase	unknown	unknown	gnl\|CDD\|223492
NZ_AP014956.1\|WP_023350692.1\|2116244_2117186_-\|malate-dehydrogenase	unknown	unknown	gnl\|CDD\|180477
NZ_AP014956.1\|WP_030059123.1\|2117630_2118557_-\|GTP-binding-protein	unknown	unknown	gnl\|CDD\|223597
NZ_AP014956.1\|WP_030059136.1\|2126838_2127135_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014956.1\|WP_096389359.1\|2129129_2129618_-\|DUF456-domain-containing-protein	unknown	unknown	gnl\|CDD\|225395
NZ_AP014956.1\|WP_030059120.1\|2114484_2116041_-\|DASS-family-sodium-coupled-anion-symporter	unknown	unknown	gnl\|CDD\|279307
NZ_AP014956.1\|WP_002433445.1\|2118781_2119222_+\|HTH-type-transcriptional-regulator-MgrA	unknown	unknown	gnl\|CDD\|197670
NZ_AP014956.1\|WP_030059125.1\|2119328_2121020_-\|thiol-reductant-ABC-exporter-subunit-CydC	unknown	unknown	gnl\|CDD\|227320
NZ_AP014956.1\|WP_030059130.1\|2124717_2125164_+\|YaiI/YqxD-family-protein	unknown	unknown	gnl\|CDD\|178882
NZ_AP014956.1\|WP_030059127.1\|2124024_2124711_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|173412
NZ_AP014956.1\|WP_002433118.1\|2122876_2123749_+\|undecaprenyl-diphosphate-phosphatase	unknown	unknown	gnl\|CDD\|234712
NZ_AP014956.1\|WP_030059134.1\|2125809_2126199_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014956.1\|WP_030059132.1\|2125177_2125744_+\|TIGR00730-family-Rossman-fold-protein	unknown	unknown	gnl\|CDD\|224527
NZ_AP014956.1\|WP_002433172.1\|2121022_2122651_-\|ABC-transporter-ATP-binding-protein/permease	unknown	unknown	gnl\|CDD\|227321
NZ_AP014956.1\|WP_002432980.1\|2126155_2126716_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112

Protein	Function_ID	Function_description	E-value
NZ_AP014956.1\|WP_030059140.1\|2127771_2128227_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	6.93055e-11
NZ_AP014956.1\|WP_002433172.1\|2121022_2122651_-\|ABC-transporter-ATP-binding-protein/permease	gnl\|CDD\|227321	COG4988, CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	2.97827e-176
NZ_AP014956.1\|WP_023350700.1\|2128370_2129060_+\|DUF1129-family-protein	gnl\|CDD\|368981	pfam06570, DUF1129, Protein of unknown function (DUF1129). This family consists of several hypothetical bacterial proteins of unknown function.	0.000399451
NZ_AP014956.1\|WP_030059118.1\|2112970_2114344_-\|deoxyribodipyrimidine-photo-lyase	gnl\|CDD\|223492	COG0415, PhrB, Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair].	4.70477e-149
NZ_AP014956.1\|WP_030059123.1\|2117630_2118557_-\|GTP-binding-protein	gnl\|CDD\|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	6.31216e-70
NZ_AP014956.1\|WP_096389359.1\|2129129_2129618_-\|DUF456-domain-containing-protein	gnl\|CDD\|225395	COG2839, COG2839, Uncharacterized protein conserved in bacteria [Function unknown].	9.30761e-35
NZ_AP014956.1\|WP_030059132.1\|2125177_2125744_+\|TIGR00730-family-Rossman-fold-protein	gnl\|CDD\|224527	COG1611, COG1611, Predicted Rossmann fold nucleotide-binding protein [General function prediction only].	2.26307e-58
NZ_AP014956.1\|WP_002433445.1\|2118781_2119222_+\|HTH-type-transcriptional-regulator-MgrA	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	6.63419e-20
NZ_AP014956.1\|WP_030059125.1\|2119328_2121020_-\|thiol-reductant-ABC-exporter-subunit-CydC	gnl\|CDD\|227320	COG4987, CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	4.77309e-175
NZ_AP014956.1\|WP_030059130.1\|2124717_2125164_+\|YaiI/YqxD-family-protein	gnl\|CDD\|178882	PRK00124, PRK00124, YaiI/YqxD family protein.	6.05743e-70
NZ_AP014956.1\|WP_030059127.1\|2124024_2124711_+\|hypothetical-protein	gnl\|CDD\|173412	PTZ00121, PTZ00121, MAEBL; Provisional.	0.00724368
NZ_AP014956.1\|WP_002433118.1\|2122876_2123749_+\|undecaprenyl-diphosphate-phosphatase	gnl\|CDD\|234712	PRK00281, PRK00281, undecaprenyl-diphosphate phosphatase.	2.2416e-101
NZ_AP014956.1\|WP_030059120.1\|2114484_2116041_-\|DASS-family-sodium-coupled-anion-symporter	gnl\|CDD\|279307	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region. There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.	2.93409e-93
NZ_AP014956.1\|WP_023350692.1\|2116244_2117186_-\|malate-dehydrogenase	gnl\|CDD\|180477	PRK06223, PRK06223, malate dehydrogenase; Reviewed.	0
NZ_AP014956.1\|WP_002432980.1\|2126155_2126716_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	7.19502e-30

>NZ_AP014956.1|WP_002433118.1|2122876_2123749_+|undecaprenyl-diphosphate-phosphatase
MFLLELIKGIILGIVEGLTEFAPVSSTGHMILVDDMWLKSTKFLGEQSAFTFKVVIQLGSVFAAAWVFRDRFLEILHIGHHKPENEGSVQRRSQPKRLNLLHVLVGMIPAGILGFLFDDLIEKYLFSVPTVMIGLFIGAIYMILADKYSEKVQHPQTVDQINYFQAFVIGISQAIAMWPGFSRSGSTISTGVFMKLNHKAASDFTFIMSVPIMLAASGLSLLKHYEYIHLAHVPFYLLGFLAAFIVGLIAIKTFLHLINKVKLIPFAIYRIVLVVIIAILYFGFGIGKGI
>NZ_AP014956.1|WP_002433172.1|2121022_2122651_-|ABC-transporter-ATP-binding-protein/permease
MKKLTNLVFKYKIYPALMLIMSVFLSISVVIQNVSIAKLLNHMLYHHKHSLIGLFILILVILLARATFNMLNQRIGDHMATKVKYDLRQQVINKNSTRAIGEQMNILTESIDGIAPFFQSYLPQVFKSMMIPVAIIVAMCYVHLSTAIIMMVTAPFIPMFYIIFGLKTRDESKDQMTYLNQFSQRFLNTAKGLITLKLLNQTKNTEARLYEDSTKFRDLTMKILKSAFLSGLMLEFISMLGIGLVALEAALSLVVFNKINFITAAIAIILAPEFYNAIKDLGQAFHTGKQSEGSSDVVFEFLDSENKPPHPHPNIEAYQKSQVKVEDVSYQYSNSNQNALTHINMVIHSGDKIAIVGPSGAGKTTLAHILSQIKTPTEGSVSFNNEDTRIGFLSQNPYIFTDSIKNNIAMFNNEISDKTIIQVLEEVGLKDKVLSLKDTIYTPIGEGGEMLSGGQMRRIELCRLLVMNPDLVIFDEPAIGLDIETERTIQNVIQNHFKDTTMIIIAHRDSTINKAQRRIYLEDGHLIKDDTTISVSQSEVDE
>NZ_AP014956.1|WP_030059125.1|2119328_2121020_-|thiol-reductant-ABC-exporter-subunit-CydC
MKSQIHFRKDKDLLLAILVGVVGGLVALAMFFLSGYMVTQSALGAPLYALMVLVVSVKMFGFLRAITRYIERLLSHRTTFTMLRDVRVQFLKKLIPAVPDIYRKFNSSDLISRMVSRVEALQNIYLRVYYPPIVIGLTAIVSVITFIFISPMHSFLITLSMILTLCIVPWLSAKKARTLKRQVALHQSHFLQRFYDYKEGDDELRRFRQRDEFKTDVLQRLKQYDTMQSKERRFLSLYDYMLNIIAMISIFLSLVIGVQQIQSGHLDVVYLTSIVLMILTLFEQAVPMSNVAYYKADTDQALDEINDVISVPQSNELHSLNHADTTTPLFEINDVTFGYWNQQTPVLNNIDLTIQEGEKVAIIGPSGSGKSTLLQVMLGLYHVDQGTVKLKHQIVTDINEEDKYYKMNGMLQSQHIFDGTVRDNLFSEKEDAILKQALQSVGLGYLDLERNVTLDGENLSGGEKQRLSLARLLLRDSADIWILDEPTTALDLENTTKTMNLIEASSKTLVIATHDLDVLPRFDKIIVMIDGEIKESGSYESLLEGNGYLSQMIEINHSSKNVH
>NZ_AP014956.1|WP_002433445.1|2118781_2119222_+|HTH-type-transcriptional-regulator-MgrA
MSDQHNLKEQLCFSLYNAQRQVNRYYSNKVFKKYNLTYPQFLVLTILWDESPVNVKKVVTELALDTGTVSPLLKRMEQVDLIKRERSEVDQREVFIHLTDKSETIRPELSTASEKVATASSLSKEEVKELNRLLGKVIDAFTETKE
>NZ_AP014956.1|WP_030059123.1|2117630_2118557_-|GTP-binding-protein
MRNNKDEKITISIISGFLGSGKTTLLTHYISEILKTDEKVKVIMNEFGSLDVDGNHLSNIVDVRSILNGCVCCDLKIDLVNQIESLVQGNETDHIIIEATGIAHPIEIIMACQDPRIVKYVRQPQVIGVVDAERFINRMQYSESTMRLMEEQLEVSHILIVNKTDLISEDKQQQLKDELNLINAQVPIILTSYGKVNIDEISQFRDDLVTTHTHSHHHGINSMQYTFSGPIDRQLFYQFILRLPDNVLRLKGYVQFRDTPNETYEFQYAYGMPDYGVIDKDLPLTIVIIGEQLDVNRLKNKLDMIQFS
>NZ_AP014956.1|WP_002433193.1|2117328_2117613_-|hypothetical-protein
MNNEDKREQQIKFEKNLITFPYLGFAIVVLLFNIFYPDIKVSMALFGLFFAYNLGLLFIAFIRHFKRTLILTLVLTVLSGAAFFTLLYVFGLRH
>NZ_AP014956.1|WP_023350692.1|2116244_2117186_-|malate-dehydrogenase
MNTRRKVSIIGAGNTGSTLAFVLAQKELADIVMIDRPQSEGFVKGKALDILESGPIFGFDTNVQGSVEIEDIQDSDIVVMTAGIPRKPGMTRDDLVQTNEEIVYQTSLNIAKYAPNATIIVLTNPVDAMTYTALKASGFPKERVIGQSGVLDTARYQSFIADELNVSVKDINGLVLGGHGDTMVPLVESTQVNGVPVKDLIAEDVLDRIVKRTRKGGAEIVELLGKGSAYYAPATAIYEMIEAILKDQKRLLPSIAYLEGEYGFSDICLGVPTILSKKGIEKIVEVNLNDKELEQLKYSAESVENVKNALKNK
>NZ_AP014956.1|WP_030059120.1|2114484_2116041_-|DASS-family-sodium-coupled-anion-symporter
MTKAKPQTHSQNQNQNTQSNKGYKPIWIIISFALLIGILLLPTPSGLPIMAKAALAILAFAVIMWVTEAVSYPVSATLILGLIILLLGFSPVQNLSEKLGNPKSGDAILKGSELLGTNNALTHAFSGFSTSAVALVAAALFLASAMQETNLHKRLALIVLSIVGNKTRNIVIGAIVVSIVLAFFVPSATARAGAVVPILLGMIAAFKMSKESKLASLLVITAVQAVSIWNIGIKTAAAQNIVAINFINQNLGHDVSWGEWFLYAAPWSILMSVALYFIMIKVMPPERDSIEGGKELIKKELNELGPVSAREWRLIAISILLLFFWSTEKLLHPIDSASITLIALGIMLMPKIGVITWKGVEKKIPWGTIIVFGVGISLGNVLLKTGAAQWLSDQTFGLMGLKGLPIIATIALITLFNILIHLGFASATSLSSALIPVFISLTSTLHLGDHAIGFVLIQQFVISFGFLLPVSAPQNMLAYGTGTFTVKDFLKTGVPLTIIGYILVIVFSLTYWKWLGLV
>NZ_AP014956.1|WP_030059118.1|2112970_2114344_-|deoxyribodipyrimidine-photo-lyase
MALGVILNRVFRTDNNPLFEYVYQNIEDIDQCYYIIPKEDFGNEAKMKRNYYYGTLQKFVHALYENDIQPFLMDYDELVDFFKEKGINEVVIAGDIMSYHKEEYDILHQRENFKKEDISVTTIRANHYFKPSKTRNNKGEPYKVFTSFYKKWRPYLMKRTVYNYDIKDLAKVGVKSKQKLKGDYSQSGISEETAQYKWSDFLDKDIEDYDSNREYLPEVLTSQLSIYLAYGVLDIIQIFNDLLDGYDKDEQNYEAFIRELIFREFYYVLMTQYPKTAHIAFKEKYQNLNWSYNEDNFDLWRKGMTGFPIIDAAMGELNTTGYMHNRMRMVVSQFLTKDLFIDWTWGEEYFRQKLIDYDAASNVHGWQWSASTGTDAVPYFRMFNPVRQSERFDKKALYIKKFIPTLNDVDAKYLHDTYKHERQIKEQGIELGKDYPKQMVNHSESRDHVMSEFKAME
>NZ_AP014956.1|WP_002433221.1|2112601_2112880_+|hypothetical-protein
MIFSIILLIVILIILQLIIGHFWHDVGFNYSKSIQLMFLPLGIGLFIMQIAYYERHYPNWDVPFKVKLRLKYMYIITFFEYVAVYICLFRLS
>NZ_AP014956.1|WP_030059127.1|2124024_2124711_+|hypothetical-protein
MDKKRLIKTLINVLPIVIVPLVVERKRIKEHPDVRKATDATTKATSKATSTISNKASDVKEYVGDKKQEFDNKRELKKIAKENDPAYIEKKGEKLAKQNRKEAEKMNKKLQKNIEKRHKEEEKQREENKKQRIKDMKKSQKYEEKVGLTPGKLDDKTEKKGEKLEKDNRKDVKKLDKKLQKNIEKRHKQEEKQQEAEKKARKKEFKKYDDYVAGSVVKQNKESDNTQG
>NZ_AP014956.1|WP_030059130.1|2124717_2125164_+|YaiI/YqxD-family-protein
MVKVIIDGDACPVVNSVIELTKGTGIFVNVLRSFSHFSHQIQPEHVKTVYVDDGTDAVDYKIVQLARKEDIVITQDYGLASLLIDKVHIVMHHKGSIYRADNIQTLLDQRYLNAQIRKQGGRHKGPPPFTKNDRLKFEQTFTNVIKQL
>NZ_AP014956.1|WP_030059132.1|2125177_2125744_+|TIGR00730-family-Rossman-fold-protein
MKRIAVYCGASKGKDPSYVKEAYELGKYMAEQGYELVFGAGSVGIMGAIQDGVLDHGGKAIGVMPRMLDEREITSQKVSELILVDSMHERKNKMTELADAFVMAPGGAGSLEEFFEMYSWAQIGIHQKPIGVFNLNGFFEPLQALIDHMIKEGFIDKKYQKLAPLFDTKEALLEGLNNYKPLGVRTYD
>NZ_AP014956.1|WP_030059134.1|2125809_2126199_+|hypothetical-protein
MFVSQYAIGFEAHLEMVLQNLIALAGARQRNQYLLISVSLPIALRTTNLHFVKEVSSRFTIALAIALRTTNLHFVKEVSSRFTIALAIALRTTNLHFVKEVSSRFTIALAIALRTTNLHFVKEVVLCNI
>NZ_AP014956.1|WP_002432980.1|2126155_2126716_-|GNAT-family-N-acetyltransferase
MGTYIETERLKLRDWEEKDLLPFQKMNANQQVRRYFPSLLSYRRSELDMKKMDEIIKDNGIGLFAVELKETGEWLGFIGVNYIPEDSKYPFKELPFYEIGWRLIPEVWGNGLATEGAQAVLSYAKEKGITELYSFTSETNLPSRKVMEKIGMTFLDNFEFPNLSKYHPLKRHVRYYIELLPSQSEG
>NZ_AP014956.1|WP_030059136.1|2126838_2127135_-|hypothetical-protein
MHEQDFNILEEQNITLPELGRELENITGRTIIDSTSEIKRVIAHLPNFESDTDTFVATYRLNHQNDFIDATFTAPKEQRDRLKEIPVHVKLISYISKA
>NZ_AP014956.1|WP_030059138.1|2127276_2127714_-|hypothetical-protein
MKKWFTLLLASTLMLTACGKSNEKASLEKSIDQLEKENKDLKKQKKDLENQKNKLKDQQDNLQKDINELPAEDSSSNSSEKDSSNSSEDKNSEDSSTTNSEQSTNSTKSKQSNQGQTPNKETQKSDSTSKNNDSKTTSNTQNSDQ
>NZ_AP014956.1|WP_030059140.1|2127771_2128227_-|GNAT-family-N-acetyltransferase
MKKMTLEDESWINEIARIHEHLISENEFNYQVTSTSMALRYEMIISRLKYANDIILINEHAGSLKGFIWAHYEPQLKIVQIEVLYVKPDFRRQGIASKLKRDIEQWANSMDAISIESTVNKENNDMVKLNENLGYQTSHLKMSKKLKGKNE
>NZ_AP014956.1|WP_023350700.1|2128370_2129060_+|DUF1129-family-protein
MKSTAQLTKENNVKSLRLNNTDREIFENYMTYIRADLSVNPHDSELMLNRILKHLIRAEDKGMLAMEFFDHDPKAHAKKEIKALPNETIKNIFKYIYHNFIFLIGMFCFLKGFIGFFIGGDSNYLYLYTFPITVIVGLFIIFLFIWMSFRTIQLQCFNNSHWVWWLTYGVIALLLITLFYVFFIPQSFLAFGPYINVSNWTFIIIAILITPIAFYVDHHFYNRDANTRM
>NZ_AP014956.1|WP_096389359.1|2129129_2129618_-|DUF456-domain-containing-protein
MTAVLWIIIILMFVLAFVGLIKPIIPSMLVMWIGFLIYQIGFNDGRLSWIFYVAMILFTLFILVADFMMNKYFVNRFGGSKVGEYTALVGVIVGCFVFPPFGIIIVPLIAVFVVELLNGFDFKKALKVSLGSVVAFLASTVAQAIIMVIMVIWFFVDVFLIN

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

12982 : 60314

Staphylococcus_phage(27.27%)

integrase,tRNA,transposase

attL 24414:24427|attR 62718:62731

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002434130.1\|12982_14269_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	7.0e-89	51.4
WP_002434554.1\|14604_15297_+	AzlC family ABC transporter permease	NA	NA	NA	NA
WP_030062311.1\|15293_15623_+	AzlD domain-containing protein	NA	NA	NA	NA
WP_030062313.1\|15914_16883_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_030062315.1\|17036_17963_+	DUF2232 domain-containing protein	NA	NA	NA	NA
WP_023349981.1\|17992_19960_+	DHH family phosphoesterase	NA	NA	NA	NA
WP_002434521.1\|19956_20403_+	50S ribosomal protein L9	NA	NA	NA	NA
WP_002434020.1\|20451_21852_+	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	9.9e-113	48.6
WP_002434422.1\|22130_23414_+	adenylosuccinate synthase	L7Y4J5	Megavirus	5.2e-68	35.1
WP_002434481.1\|24352_25054_+	response regulator transcription factor	W8CYM9	Bacillus_phage	2.3e-41	38.3
24414:24427	attL	NA	NA	NA	NA
WP_096389077.1\|25066_26899_+	cell wall metabolism sensor histidine kinase WalK	Q8QKV7	Ectocarpus_siliculosus_virus	2.2e-11	25.1
WP_002434631.1\|26891_28229_+	two-component system regulatory protein YycI	NA	NA	NA	NA
WP_030065550.1\|28229_29018_+	two-component system regulatory protein YycI	NA	NA	NA	NA
WP_030065548.1\|29642_30425_+	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	1.5e-38	37.0
WP_030065546.1\|30836_31316_+	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_000566670.1\|31637_32894_+	DUF3578 domain-containing protein	NA	NA	NA	NA
WP_001282729.1\|33308_33551_+	hypothetical protein	NA	NA	NA	NA
WP_096389079.1\|33578_34253_-\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	4.9e-126	97.3
WP_000664728.1\|34546_35023_+	aminoglycoside nucleotidyltransferase ANT4	NA	NA	NA	NA
WP_096389079.1\|35664_36339_-\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	4.9e-126	97.3
WP_000119405.1\|37657_38920_-	plasmid recombination protein	NA	NA	NA	NA
WP_001242578.1\|39426_39831_-	bleomycin binding protein	NA	NA	NA	NA
WP_001795128.1\|40047_40818_-	aminoglycoside O-nucleotidyltransferase ANT(4')-Ia	NA	NA	NA	NA
WP_096389079.1\|41009_41684_-\|transposase	IS6 family transposase	A0A0N9RU54	Staphylococcus_phage	4.9e-126	97.3
WP_000958858.1\|42905_43649_+	glycerophosphoryl diester phosphodiesterase	NA	NA	NA	NA
WP_000872606.1\|43745_44174_+	MaoC family dehydratase	NA	NA	NA	NA
WP_001801873.1\|44219_46229_-	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA	NA	NA	NA	NA
WP_000952923.1\|46325_48083_+	beta-lactam sensor/signal transducer MecR1	NA	NA	NA	NA
WP_000369214.1\|48082_48454_+	mecA-type methicillin resistance repressor MecI	NA	NA	NA	NA
WP_014532405.1\|48538_48607_-	phenol-soluble modulin PSM-mec	NA	NA	NA	NA
WP_010922808.1\|48940_50071_+	ROK family transcriptional regulator	NA	NA	NA	NA
WP_000438836.1\|51551_52616_-	DsrE/DsrF/DrsH-like family protein	NA	NA	NA	NA
WP_000220507.1\|52751_53012_+	persulfide-sensing transcriptional repressor CstR	NA	NA	NA	NA
WP_000350222.1\|53011_53656_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_001092058.1\|53994_54657_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_010959190.1\|55048_55108_+	erythromycin resistance leader peptide	NA	NA	NA	NA
WP_001072201.1\|55165_55897_+	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A)	E4ZFQ0	Streptococcus_phage	1.9e-51	47.5
WP_000067268.1\|56022_56805_-	aminoglycoside nucleotidyltransferase ANT(9)-Ia	NA	NA	NA	NA
WP_000361059.1\|56955_57333_-\|transposase	transposase	NA	NA	NA	NA
WP_001557544.1\|57339_59232_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_000868132.1\|59228_60314_-\|integrase	tyrosine-type recombinase/integrase	A0A0A8WIF9	Clostridium_phage	4.5e-12	28.3
62718:62731	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1011427 : 1051843

Staphylococcus_phage(96.3%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002434680.1\|1011427_1012831_+	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.3e-170	60.6
WP_049427393.1\|1012827_1013829_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	2.7e-96	50.9
WP_029625717.1\|1013825_1014074_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	3.1e-38	90.2
WP_049427390.1\|1014144_1014618_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	8.7e-45	55.1
WP_049427387.1\|1014598_1015384_+	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	3.6e-104	73.7
WP_002434740.1\|1015461_1017054_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	1.9e-285	89.8
WP_023350065.1\|1017429_1018623_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	5.7e-194	86.1
WP_002434861.1\|1018733_1019642_+	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	2.6e-106	82.5
WP_049427380.1\|1019797_1020637_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	2.7e-118	71.8
WP_023350066.1\|1020714_1021071_-	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	3.2e-07	32.8
WP_023350067.1\|1021067_1021430_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	2.1e-38	64.2
WP_002434733.1\|1021485_1021794_-	hypothetical protein	NA	NA	NA	NA
WP_002434689.1\|1022086_1022800_+	transaldolase	R9TM64	Synechococcus_phage	1.3e-20	36.5
WP_049427378.1\|1022955_1023399_+	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	1.8e-23	48.3
WP_002434754.1\|1023385_1023829_-	competence protein ComK	NA	NA	NA	NA
WP_049427376.1\|1023848_1024319_-	sigma-70 family RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	4.6e-30	45.5
WP_002434817.1\|1024527_1024746_+	hypothetical protein	NA	NA	NA	NA
WP_002434844.1\|1025061_1025913_+	N-acetylglucosaminidase	A0A1J0MFB0	Staphylococcus_phage	4.0e-32	34.5
WP_070597874.1\|1026228_1027719_+	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	1.4e-19	89.3
WP_096389229.1\|1028127_1029177_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	3.0e-138	68.1
WP_049427367.1\|1029183_1029816_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	3.4e-89	77.1
WP_023350073.1\|1029827_1031009_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	3.9e-179	76.6
WP_002434688.1\|1031051_1031510_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	7.1e-60	84.9
WP_096389230.1\|1031576_1032578_-	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	1.5e-134	72.9
WP_049427363.1\|1032824_1033652_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_002434669.1\|1034065_1034467_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_002434676.1\|1034544_1035108_-	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	3.5e-69	67.6
WP_002434687.1\|1035104_1036058_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	7.8e-69	86.8
WP_070597871.1\|1036164_1037388_+	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	7.9e-183	80.9
WP_172969458.1\|1037679_1040097_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	88.2
WP_002434691.1\|1040117_1040429_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	7.4e-37	74.8
WP_096389232.1\|1040734_1051843_+	DUF1542 domain-containing protein	A0A2H4PQU6	Staphylococcus_phage	2.2e-58	34.9

DBSCAN-SWA_3

1175441 : 1186991

uncultured_Mediterranean_phage(57.14%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002436053.1\|1175441_1176446_+	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	2.2e-05	29.1
WP_002436078.1\|1176447_1177473_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_049427500.1\|1177495_1178635_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	4.9e-86	45.3
WP_002436110.1\|1178650_1178914_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	4.4e-06	44.1
WP_096389260.1\|1179149_1181441_+	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	7.4e-33	35.2
WP_070597847.1\|1181580_1183854_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	4.1e-68	29.2
WP_002453394.1\|1183872_1184391_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	3.3e-29	45.8
WP_002436070.1\|1184801_1186991_+	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A1B1IUF0	uncultured_Mediterranean_phage	2.0e-11	37.2

DBSCAN-SWA_4

1664890 : 1734456

Staphylococcus_phage(70.97%)

tRNA,holin,terminase,integrase,tail,portal,protease,plate

attL 1677042:1677057|attR 1741431:1741446

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049428507.1\|1664890_1667641_-\|tRNA	isoleucine--tRNA ligase	A0A2I2L3Y0	Orpheovirus	2.8e-87	26.6
WP_030065292.1\|1667966_1668620_-	DivIVA domain-containing protein	NA	NA	NA	NA
WP_030065290.1\|1668643_1669432_-	RNA-binding protein	NA	NA	NA	NA
WP_023350429.1\|1669552_1669843_-	YggT family protein	NA	NA	NA	NA
WP_030065288.1\|1669854_1670466_-	cell division protein SepF	NA	NA	NA	NA
WP_002435178.1\|1670462_1671137_-	YggS family pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_030065286.1\|1671154_1671946_-	peptidoglycan editing factor PgeF	NA	NA	NA	NA
WP_030065284.1\|1672198_1673386_-	cell division protein FtsZ	NA	NA	NA	NA
WP_002435260.1\|1673418_1674819_-	cell division protein FtsA	NA	NA	NA	NA
WP_030065282.1\|1674922_1676338_-	FtsQ-type POTRA domain-containing protein	NA	NA	NA	NA
WP_002435137.1\|1676353_1677703_-	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	NA	NA	NA	NA
1677042:1677057	attL	NA	NA	NA	NA
WP_023350433.1\|1677704_1678670_-	phospho-N-acetylmuramoyl-pentapeptide- transferase	NA	NA	NA	NA
WP_023350434.1\|1678849_1681195_-	penicillin-binding protein	NA	NA	NA	NA
WP_023350435.1\|1681175_1681577_-	cell division protein FtsL	NA	NA	NA	NA
WP_002435203.1\|1681589_1682525_-	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	NA	NA	NA	NA
WP_002435248.1\|1682539_1682971_-	division/cell wall cluster transcriptional repressor MraZ	NA	NA	NA	NA
WP_030065277.1\|1683114_1684728_-	bacillithiol biosynthesis cysteine-adding enzyme BshC	NA	NA	NA	NA
WP_030065275.1\|1684915_1685356_+	N-acetyltransferase	NA	NA	NA	NA
WP_030065273.1\|1685408_1686095_-	noncanonical pyrimidine nucleotidase, YjjG family	NA	NA	NA	NA
WP_016898755.1\|1686210_1686345_-	beta-class phenol-soluble modulin	NA	NA	NA	NA
WP_096389327.1\|1686395_1686530_-	beta-class phenol-soluble modulin	NA	NA	NA	NA
WP_002435168.1\|1686585_1686720_-	beta-class phenol-soluble modulin	NA	NA	NA	NA
WP_002435197.1\|1686763_1686898_-	beta-class phenol-soluble modulin	NA	NA	NA	NA
WP_002442393.1\|1687654_1688827_+	MFS transporter	NA	NA	NA	NA
WP_002442391.1\|1689027_1690410_-	N-acetylmuramoyl-L-alanine amidase	A1BU77	Staphylococcus_virus	6.5e-258	89.6
WP_002442389.1\|1690409_1690676_-\|holin	phage holin	A0A1W6JPF8	Staphylococcus_phage	1.3e-34	77.3
WP_002442387.1\|1690727_1691123_-	hypothetical protein	A0A1W6JNM7	Staphylococcus_phage	2.4e-32	56.5
WP_002442385.1\|1691109_1691532_-	hypothetical protein	A0A1W6JNI9	Staphylococcus_phage	4.7e-34	52.3
WP_002442383.1\|1691569_1691710_-	XkdX family protein	NA	NA	NA	NA
WP_002442381.1\|1691693_1692050_-	hypothetical protein	W5RV37	Staphylococcus_phage	7.7e-22	44.2
WP_002442379.1\|1692064_1693783_-\|plate	BppU family phage baseplate upper protein	A0A060AKT8	Staphylococcus_phage	6.2e-133	57.7
WP_002442377.1\|1693782_1696446_-	hypothetical protein	A0A060AKF8	Staphylococcus_phage	4.3e-290	67.6
WP_002442375.1\|1696457_1696901_-	hypothetical protein	Q4ZCD3	Staphylococcus_virus	1.3e-13	39.0
WP_002442374.1\|1696893_1698465_-\|tail	phage tail protein	A0A2H4J2R7	uncultured_Caudovirales_phage	3.1e-208	67.0
WP_002442372.1\|1698473_1699310_-\|tail	phage tail family protein	A0A2H4J7E0	uncultured_Caudovirales_phage	3.9e-72	49.5
WP_044466295.1\|1699324_1705501_-\|tail	phage tail tape measure protein	Q8LTH9	Staphylococcus_phage	1.4e-283	53.7
WP_002442368.1\|1705515_1705674_-	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	3.5e-11	62.7
WP_044466296.1\|1705724_1706066_-	hypothetical protein	A0A0K1LKJ0	Staphylococcus_phage	7.9e-32	62.8
WP_002442364.1\|1706107_1706335_-	hypothetical protein	A0A1X9SIM4	Staphylococcus_phage	2.5e-10	50.7
WP_044466297.1\|1706346_1707003_-\|tail	tail protein	A0A2I6PE59	Staphylococcus_phage	8.2e-86	75.9
WP_002442358.1\|1707044_1707440_-	DUF3168 domain-containing protein	A0A2I6PDD8	Staphylococcus_phage	8.0e-44	66.2
WP_049306929.1\|1707441_1707843_-	hypothetical protein	R4WAN5	Staphylococcus_phage	2.6e-50	73.7
WP_002442353.1\|1707839_1708202_-	hypothetical protein	A0A2I6PDD6	Staphylococcus_phage	4.6e-22	43.9
WP_002442352.1\|1708182_1708482_-	hypothetical protein	A0A2H4JAM0	uncultured_Caudovirales_phage	1.8e-16	47.3
WP_002442348.1\|1709707_1710457_-\|protease	Clp protease ClpP	A0A1W6JPK0	Staphylococcus_phage	2.3e-60	47.0
WP_002442346.1\|1710443_1711604_-\|portal	phage portal protein	A0A2I6PDI1	Staphylococcus_phage	2.7e-116	53.2
WP_002442344.1\|1711619_1713260_-\|terminase	terminase large subunit	A0A059T7Q8	Listeria_phage	3.2e-227	69.3
WP_002442342.1\|1713256_1713559_-\|terminase	P27 family phage terminase small subunit	Q4ZD78	Staphylococcus_phage	4.4e-18	51.1
WP_002442340.1\|1713707_1714043_-	HNH endonuclease	D2XR61	Bacillus_phage	4.1e-25	55.5
WP_002442338.1\|1714177_1714612_-	transcriptional regulator	B5WZN8	Staphylococcus_phage	1.3e-66	88.1
WP_002442336.1\|1714624_1714771_-	hypothetical protein	NA	NA	NA	NA
WP_002442335.1\|1714788_1715388_-	hypothetical protein	D2JLD8	Staphylococcus_phage	1.8e-34	42.2
WP_002442333.1\|1715544_1715715_-	hypothetical protein	A0A1W6JPC7	Staphylococcus_phage	5.1e-16	76.5
WP_002442331.1\|1715751_1716177_-	dUTP diphosphatase	A0A1W6JNN6	Staphylococcus_phage	5.2e-73	99.3
WP_153227380.1\|1716176_1716347_-	hypothetical protein	A0A1W6JNR7	Staphylococcus_phage	6.3e-22	100.0
WP_126493813.1\|1716390_1716483_-	DUF1024 family protein	NA	NA	NA	NA
WP_002442327.1\|1716484_1716661_-	hypothetical protein	A0A1W6JNN8	Staphylococcus_phage	1.2e-28	100.0
WP_002442325.1\|1716647_1716926_-	hypothetical protein	NA	NA	NA	NA
WP_160312604.1\|1717004_1717379_-	hypothetical protein	A0A2R3ZXY5	Staphylococcus_phage	4.9e-11	37.6
WP_002442321.1\|1717378_1717816_-	DNA N-6-adenine-methyltransferase	A0A1W6JNN4	Staphylococcus_phage	8.5e-71	99.2
WP_002442319.1\|1717812_1718220_-	hypothetical protein	A0A2H4J9W1	uncultured_Caudovirales_phage	5.4e-11	31.9
WP_002442318.1\|1718233_1718392_-	hypothetical protein	A0A1W6JNP9	Staphylococcus_phage	1.4e-20	98.1
WP_002442316.1\|1718394_1718583_-	hypothetical protein	NA	NA	NA	NA
WP_002442314.1\|1718572_1718803_-	DUF3310 domain-containing protein	A0A0D4DCF1	Staphylococcus_phage	5.9e-23	68.6
WP_096389329.1\|1719004_1719322_-	hypothetical protein	H9A0Z8	Staphylococcus_phage	1.5e-32	70.0
WP_002442308.1\|1719371_1719566_-	hypothetical protein	A0A1W6JNR4	Staphylococcus_phage	9.7e-27	96.9
WP_002442307.1\|1719558_1719966_-	DUF1064 domain-containing protein	A0A1W6JNS0	Staphylococcus_phage	1.6e-71	96.3
WP_002442305.1\|1719974_1720220_-	hypothetical protein	A0A1W6JNN7	Staphylococcus_phage	3.0e-41	98.8
WP_002442304.1\|1720222_1720378_-	hypothetical protein	A0A1W6JNM0	Staphylococcus_phage	2.8e-21	100.0
WP_037541374.1\|1720371_1721142_-	ATP-binding protein	A0A1W6JNQ7	Staphylococcus_phage	8.3e-138	95.7
WP_096389332.1\|1721152_1721932_-	conserved phage C-terminal domain-containing protein	A6M985	Geobacillus_virus	2.4e-39	66.7
WP_002442301.1\|1721918_1722680_-	HNH endonuclease	A0A125RNK0	Pseudomonas_phage	2.0e-35	37.9
WP_037541373.1\|1722672_1722879_-	helix-turn-helix transcriptional regulator	Q4ZC20	Staphylococcus_virus	1.6e-19	66.2
WP_002442299.1\|1722884_1723115_-	helix-turn-helix transcriptional regulator	A0A1W6JPR2	Staphylococcus_phage	7.4e-26	71.1
WP_002442298.1\|1723111_1723780_-	hypothetical protein	A0A1W6JPR0	Staphylococcus_phage	6.4e-102	79.6
WP_002442297.1\|1723780_1724329_-	HNH endonuclease	A0A1W6JNF8	Staphylococcus_phage	2.4e-83	81.3
WP_002442296.1\|1724341_1724896_-	single-stranded DNA-binding protein	A0A0H3U303	Staphylococcus_phage	3.2e-91	88.6
WP_002442295.1\|1724922_1725699_-	ATP-binding protein	Q8SDW5	Staphylococcus_phage	1.3e-125	87.3
WP_002442294.1\|1725699_1726185_-	siphovirus Gp157 family protein	A0A2H4JCW3	uncultured_Caudovirales_phage	2.5e-71	88.2
WP_002442292.1\|1726150_1726432_-	hypothetical protein	A0A1W6JNM8	Staphylococcus_phage	3.1e-18	96.2
WP_162837223.1\|1726493_1726667_-	hypothetical protein	A0A1W6JNL3	Staphylococcus_phage	1.9e-21	96.5
WP_002442287.1\|1726680_1726890_-	hypothetical protein	A0A1W6JNP3	Staphylococcus_phage	2.6e-30	94.2
WP_002442285.1\|1726978_1727455_+	hypothetical protein	NA	NA	NA	NA
WP_002442282.1\|1727417_1727651_-	hypothetical protein	NA	NA	NA	NA
WP_002442280.1\|1727689_1728481_-	phage antirepressor Ant	A0A2H4J5J5	uncultured_Caudovirales_phage	1.9e-116	80.6
WP_009382133.1\|1728480_1728675_-	helix-turn-helix transcriptional regulator	A0A0F6N3M9	Staphylococcus_phage	1.1e-22	89.1
WP_002442276.1\|1728938_1729277_+	helix-turn-helix transcriptional regulator	R4IH08	Staphylococcus_phage	1.7e-42	74.5
WP_037541370.1\|1729290_1729962_+	ImmA/IrrE family metallo-endopeptidase	A0A0F6N3H6	Staphylococcus_phage	5.0e-46	46.6
WP_002442272.1\|1729988_1730564_+	hypothetical protein	A0A2H4IYV6	uncultured_Caudovirales_phage	3.5e-16	68.6
WP_002442271.1\|1730812_1731880_+	Abi family protein	A0A2H4JB40	uncultured_Caudovirales_phage	2.4e-82	50.7
WP_002442268.1\|1731943_1732990_+\|integrase	site-specific integrase	A0A2H4J9L9	uncultured_Caudovirales_phage	1.2e-147	73.0
WP_030065271.1\|1733366_1733876_-	metallophosphoesterase	NA	NA	NA	NA
WP_030065269.1\|1733868_1734456_-	XTP/dITP diphosphatase	A0A068ESG1	Cassava_brown_streak_virus	4.0e-07	36.2
1741431:1741446	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1820051 : 1828521

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_030065175.1\|1820051_1820618_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.2e-30	42.0
WP_030065174.1\|1820614_1821649_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.1e-63	42.4
WP_096389342.1\|1821641_1823126_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	8.5e-46	32.2
WP_064212240.1\|1823104_1825294_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	3.1e-137	39.6
WP_023350479.1\|1825286_1825958_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_030065170.1\|1825959_1826220_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_030065168.1\|1826216_1826924_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	H8ZMN3	Synechococcus_phage	2.8e-47	43.7
WP_002435349.1\|1826924_1828052_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_030065166.1\|1828038_1828521_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.0e-20	40.8

DBSCAN-SWA_6

1992094 : 2012713

Streptococcus_phage(90.0%)

integrase

attL 2005130:2005144|attR 2011276:2011290

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000420682.1\|1992094_1992409_+	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
WP_000985015.1\|1992424_1992811_+	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_000813488.1\|1992839_1994225_+	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000879507.1\|1994227_1994380_+	hypothetical protein	NA	NA	NA	NA
WP_000398284.1\|1994402_1995608_+	replication initiation factor domain-containing protein	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
WP_001009056.1\|1995650_1995872_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000342539.1\|1995988_1996486_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
WP_000506270.1\|1996460_1996967_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_000331160.1\|1996950_1999398_+	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
WP_000804748.1\|1999400_2001578_+	membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
WP_000769868.1\|2001574_2002576_+	bifunctional lysozyme/C40 family peptidase	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
WP_001224318.1\|2002572_2003505_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	3.1e-171	99.4
WP_001814923.1\|2003749_2003866_+	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_000691736.1\|2003881_2005801_+	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	99.5
2005130:2005144	attL	NA	NA	NA	NA
WP_000336323.1\|2005919_2006087_+	cysteine-rich KTR domain-containing protein	D0R0F6	Streptococcus_phage	1.6e-14	68.0
WP_001227347.1\|2006146_2006500_-	helix-turn-helix domain-containing protein	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
WP_000804885.1\|2007004_2007427_+	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
WP_000857133.1\|2007423_2007654_+	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
WP_000814511.1\|2008114_2008318_+	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
WP_001291561.1\|2008399_2009617_+\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
WP_023350637.1\|2009946_2010693_+	poly-gamma-glutamate hydrolase family protein	A0A2H4IZ42	uncultured_Caudovirales_phage	2.4e-41	42.4
WP_030064982.1\|2010813_2011098_+	hypothetical protein	NA	NA	NA	NA
WP_002433282.1\|2011121_2011346_+	hypothetical protein	NA	NA	NA	NA
2011276:2011290	attR	NA	NA	NA	NA
WP_030064980.1\|2011655_2012390_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_002433447.1\|2012512_2012713_-	cold-shock protein	Q9AZD3	Lactococcus_phage	5.9e-19	67.7

DBSCAN-SWA_7

2091877 : 2099383

Pandoravirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_030063462.1\|2091877_2093032_-	aminodeoxychorismate synthase component I	A0A0B5J984	Pandoravirus	1.3e-25	36.1
WP_030063460.1\|2093021_2093609_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	4.1e-36	39.6
WP_002433505.1\|2093915_2094587_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	2.6e-63	54.0
WP_002433142.1\|2094588_2095008_+	6-carboxytetrahydropterin synthase QueD	NA	NA	NA	NA
WP_030063457.1\|2095011_2095725_+	7-carboxy-7-deazaguanine synthase QueE	E7DN68	Pneumococcus_phage	8.5e-52	43.5
WP_002433459.1\|2095824_2096424_+	hypothetical protein	NA	NA	NA	NA
WP_030059103.1\|2096704_2097142_+	DM13 domain-containing protein	NA	NA	NA	NA
WP_002433139.1\|2097193_2097667_+	DoxX family protein	NA	NA	NA	NA
WP_030059105.1\|2097641_2098331_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.8e-35	35.7
WP_030059107.1\|2098333_2099383_+	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	2.4e-18	30.5

DBSCAN-SWA_8

2392004 : 2408246

Staphylococcus_phage(45.0%)

integrase,terminase

attL 2394061:2394075|attR 2416132:2416146

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049401922.1\|2392004_2392574_-\|terminase	terminase small subunit	A0A2H4JBF3	uncultured_Caudovirales_phage	1.8e-92	90.0
WP_053026909.1\|2392575_2392917_-	sigma-70 family RNA polymerase sigma factor	A0A2H4JEH8	uncultured_Caudovirales_phage	7.4e-22	48.2
WP_096389383.1\|2392913_2393351_-	pathogenicity island protein	A0A2H4JBD6	uncultured_Caudovirales_phage	2.0e-67	93.1
WP_070441482.1\|2393402_2393615_-	hypothetical protein	A0A2H4JHW4	uncultured_Caudovirales_phage	1.0e-13	62.3
WP_096389386.1\|2393614_2394202_-	pathogenicity island protein	A0A2H4JBG0	uncultured_Caudovirales_phage	2.8e-77	79.1
2394061:2394075	attL	NA	NA	NA	NA
WP_096389389.1\|2394216_2394969_-	hypothetical protein	A0A2H4JD56	uncultured_Caudovirales_phage	4.5e-128	94.8
WP_002476284.1\|2394978_2395311_-	hypothetical protein	A0A2H4JHK4	uncultured_Caudovirales_phage	4.2e-54	99.1
WP_096389393.1\|2395669_2396254_-	hypothetical protein	NA	NA	NA	NA
WP_096389396.1\|2396250_2396895_-	pathogenicity island protein	Q4ZE67	Staphylococcus_phage	7.1e-82	69.0
WP_096389399.1\|2396896_2397178_-	pathogenicity island protein	A0A1W6JQE4	Staphylococcus_phage	8.2e-35	75.6
WP_002502283.1\|2397179_2397542_-	hypothetical protein	A0A1W6JQD5	Staphylococcus_phage	7.8e-54	80.8
WP_096389402.1\|2397813_2399301_-	virulence-associated protein E	A0A1W6JQD6	Staphylococcus_phage	2.5e-255	87.4
WP_096389404.1\|2399313_2400186_-	primase alpha helix C-terminal domain-containing protein	A0A1W6JQL5	Staphylococcus_phage	7.4e-74	50.5
WP_096389407.1\|2400283_2400622_-	hypothetical protein	A0A2H4JBC6	uncultured_Caudovirales_phage	7.9e-16	41.1
WP_096389410.1\|2400623_2400983_-	pathogenicity island protein	NA	NA	NA	NA
WP_096389413.1\|2401001_2401274_-	helix-turn-helix domain-containing protein	A7TWG0	Staphylococcus_phage	1.0e-10	45.0
WP_096389416.1\|2401274_2401487_-	helix-turn-helix transcriptional regulator	Q4ZE78	Staphylococcus_phage	2.4e-18	64.3
WP_096389418.1\|2401630_2402326_+	helix-turn-helix transcriptional regulator	Q4ZE79	Staphylococcus_phage	8.9e-14	36.8
WP_096389420.1\|2402359_2403676_+	DUF4041 domain-containing protein	M1NRY5	Streptococcus_phage	5.7e-62	43.0
WP_096389422.1\|2403697_2404915_+\|integrase	site-specific integrase	A7TWE6	Staphylococcus_phage	7.8e-98	48.6
WP_023349905.1\|2405059_2406601_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	4.7e-23	32.1
WP_030061277.1\|2406779_2408246_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	1.4e-93	40.0
2416132:2416146	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_AP014956

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection