CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP022098	Cystobacter fuscus strain DSM 52655 chromosome, complete genome	23 crisprs	cas3,WYL,csa3,2OG_CAS,RT,DinG	10	8	2	1

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP022098_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_1

43642-43718

Orphan

Consensus_repeat	Method
AGGTTCTGGAGCTGCGACTGGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022098_1

>merge|NZ_CP022098|1|43642-43718|CRISPRCasFinder
AGGTTCTGGAGCTGCGACTGGGCGTTGGCCGTGGGGGCGGGCGCGTTGCCGAGGAGGTTCTGGAGCTGCGACTGGGC

>NZ_CP022098|1|1|43642-43718|CRISPRCasFinder
AGGTTCTGGAGCTGCGACTGGGC	GTTGGCCGTGGGGGCGGGCGCGTTGCCGAGG
AGGTTCTGGAGCTGCGACTGGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_095983364.1\|57340_58537_-\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|380547
NZ_CP022098.1\|WP_095983356.1\|39181_42586_+\|DUF853-family-protein	unknown	unknown	gnl\|CDD\|223510
NZ_CP022098.1\|WP_095983354.1\|36848_38129_+\|DUF559-domain-containing-protein	unknown	unknown	gnl\|CDD\|238509
NZ_CP022098.1\|WP_095991717.1\|46216_46567_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095983360.1\|48892_50158_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095991716.1\|34318_35116_-\|methyltransferase	unknown	unknown	gnl\|CDD\|226608
NZ_CP022098.1\|WP_095983353.1\|35764_36724_-\|glutathione-synthase	unknown	unknown	gnl\|CDD\|235371
NZ_CP022098.1\|WP_095983349.1\|30212_31385_-\|S8-family-serine-peptidase	unknown	unknown	gnl\|CDD\|173799
NZ_CP022098.1\|WP_095983355.1\|38115_39144_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236999
NZ_CP022098.1\|WP_095983358.1\|45183_46038_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212492
NZ_CP022098.1\|WP_157758137.1\|31630_32527_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095983365.1\|58824_59751_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234609
NZ_CP022098.1\|WP_095983351.1\|32764_34315_+\|carbohydrate-esterase	unknown	unknown	gnl\|CDD\|225375
NZ_CP022098.1\|WP_095983362.1\|52505_55271_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP022098.1\|WP_157758136.1\|29148_30126_-\|DUF3396-domain-containing-protein	unknown	unknown	gnl\|CDD\|371775
NZ_CP022098.1\|WP_095991718.1\|51085_52408_-\|FHA-domain-containing-protein	unknown	unknown	gnl\|CDD\|225114
NZ_CP022098.1\|WP_157758138.1\|35246_35747_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095983363.1\|55353_57354_-\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|223715
NZ_CP022098.1\|WP_095983359.1\|46686_48504_-\|M4-family-metallopeptidase	unknown	unknown	gnl\|CDD\|341060
NZ_CP022098.1\|WP_095983361.1\|50364_50973_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095983356.1\|39181_42586_+\|DUF853-family-protein	gnl\|CDD\|223510	COG0433, COG0433, HerA helicase [Replication, recombination, and repair].	3.84058e-08
NZ_CP022098.1\|WP_095983354.1\|36848_38129_+\|DUF559-domain-containing-protein	gnl\|CDD\|238509	cd01038, Endonuclease_DUF559, Domain of unknown function, appears to be related to a diverse group of endonucleases.	4.89323e-09
NZ_CP022098.1\|WP_095983365.1\|58824_59751_+\|hypothetical-protein	gnl\|CDD\|234609	PRK00068, PRK00068, hypothetical protein; Validated.	0.00633414
NZ_CP022098.1\|WP_095991716.1\|34318_35116_-\|methyltransferase	gnl\|CDD\|226608	COG4123, COG4123, Predicted O-methyltransferase [General function prediction only].	3.45064e-52
NZ_CP022098.1\|WP_095983353.1\|35764_36724_-\|glutathione-synthase	gnl\|CDD\|235371	PRK05246, PRK05246, glutathione synthetase; Provisional.	8.96513e-155
NZ_CP022098.1\|WP_095983349.1\|30212_31385_-\|S8-family-serine-peptidase	gnl\|CDD\|173799	cd07473, Peptidases_S8_Subtilisin_like, Peptidase S8 family domain in Subtilisin-like proteins. This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	8.11979e-87
NZ_CP022098.1\|WP_095983355.1\|38115_39144_+\|hypothetical-protein	gnl\|CDD\|236999	PRK11854, aceF, pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated.	0.000519172
NZ_CP022098.1\|WP_095983358.1\|45183_46038_-\|SDR-family-oxidoreductase	gnl\|CDD\|212492	cd05327, retinol-DH_like_SDR_c_like, retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs. Classical SDR subgroup containing retinol-DHs, LPORs, and related proteins. Retinol is processed by a medium chain alcohol dehydrogenase followed by retinol-DHs. Pchlide reductases act in chlorophyll biosynthesis. There are distinct enzymes that catalyze Pchlide reduction in light or dark conditions. Light-dependent reduction is via an NADP-dependent SDR, LPOR. Proteins in this subfamily share the glycine-rich NAD-binding motif of the classical SDRs, have a partial match to the canonical active site tetrad, but lack the typical active site Ser. This subgroup includes the human proteins: retinol dehydrogenase -12, -13 ,and -14, dehydrogenase/reductase SDR family member (DHRS)-12 , -13 and -X (a DHRS on chromosome X), and WWOX (WW domain-containing oxidoreductase), as well as a Neurospora crassa SDR encoded by the blue light inducible bli-4 gene. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	4.81148e-110
NZ_CP022098.1\|WP_095983351.1\|32764_34315_+\|carbohydrate-esterase	gnl\|CDD\|225375	COG2819, COG2819, Predicted hydrolase of the alpha/beta superfamily [General function prediction only].	2.12505e-35
NZ_CP022098.1\|WP_095983362.1\|52505_55271_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.03522e-81
NZ_CP022098.1\|WP_157758136.1\|29148_30126_-\|DUF3396-domain-containing-protein	gnl\|CDD\|371775	pfam11876, DUF3396, Protein of unknown function (DUF3396). This family of proteins are functionally uncharacterized. This protein is found in bacteria and viruses. Proteins in this family are typically between 302 to 382 amino acids in length.	4.59745e-51
NZ_CP022098.1\|WP_095991718.1\|51085_52408_-\|FHA-domain-containing-protein	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	2.58423e-117
NZ_CP022098.1\|WP_095983363.1\|55353_57354_-\|GAF-domain-containing-protein	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.43642e-44
NZ_CP022098.1\|WP_095983359.1\|46686_48504_-\|M4-family-metallopeptidase	gnl\|CDD\|341060	cd09597, M4_TLP, Peptidase M4 family including thermolysin, protealysin, aureolysin, and neutral protease. This peptidase M4 family includes several endopeptidases such as thermolysin (EC 3.4.24.27), aureolysin (the extracellular metalloproteinase from Staphylococcus aureus), neutral protease from Bacillus cereus, protealysin, and bacillolysin (EC 3.4.24.28). Typically, the M4 peptidases consist of a presequence (signal sequence), a propeptide sequence, and a peptidase unit. The presequence is cleaved off during export while the propeptide has inhibitory and chaperone functions and facilitates folding. The propeptide remains attached until the peptidase is secreted and can be safely activated. All peptidases in this family bind a single catalytic zinc ion which is tetrahedrally co-ordinated by three amino acid ligands and a water molecule that forms the nucleophile on activation during catalysis. The active site is found between two sub-domains; the N-terminal domain contains the HEXXH zinc-binding motif while the helical C-terminal domain, which is unique for the family, carries the third zinc ligand. These peptidases are secreted eubacterial endopeptidases from Gram-positive or Gram-negative sources that degrade extracellular proteins and peptides for bacterial nutrition. They are selectively inhibited by Steptomyces metalloproteinase inhibitor (SMPI) as well as by phosphoramidon from Streptomyces tanashiensis. A large number of these enzymes are implicated as key factors in the pathogenesis of various diseases, including gastritis, peptic ulcer, gastric carcinoma, cholera and several types of bacterial infections, and are therefore important drug targets. Some enzymes of the family can function at extremes of temperatures, while some function in organic solvents, thus rendering them novel targets for biotechnological applications. Thermolysin is widely used as a nonspecific protease to obtain fragments for peptide sequencing. It has also been used in production of the artificial sweetener aspartame.	1.56753e-119
NZ_CP022098.1\|WP_095983364.1\|57340_58537_-\|substrate-binding-domain-containing-protein	gnl\|CDD\|380547	cd06324, PBP1_ABC_sugar_binding-like, periplasmic sugar-binding domain of uncharacterized ABC-type transport systems. This group includes the periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.	2.05191e-121

>NZ_CP022098.1|WP_095983356.1|39181_42586_+|DUF853-family-protein
MNPHDSRLAAFLSDRTEVFHSIQHRHEVWREDPFDVESIHQDARATFERMLQRATTPPGTPSGRILLLLGDSGCGKTHLLRTFRSLVHERSLGFVGYLQMTTSTSNYGRYVLSNLIDSLDQPYCEPGEPRSGLRKLSDVLLSQCGPVAALLADPEQDPEEIPVLVESAADDLQKQPAFEKLDLDLLRALLYLQRDDTRIRSRVLKYLRCEDLSTSDRKVLGGMVPRTYDNHPQEMVQHLGRLMATLNQSLVLCVDQLEGFDVEAAQAQAFQRAMHLLCDFAESAPSSLIVISCLHTFWTGLREKLHRSTLDRIERDPEPLKLENQRSVDEARRITERRLEHLYSMEDAPFDPAEPTYPFPHEGFERLAGLTTREVLDACRRWREQAVRDQALPAQFPLRDAPKETRPPPNETKKLLALDQAWNDFRSTQATPPPEEDGPLAELLVWALKAIADELETGHRFDVRRLGEVLQVDVSPGDEKLHVALCNRGTQGGGLANQIEQTRKEARGRTPVVIRTSDFPSNPKTQAAAELGKLLSKGGRRAVLEDSDSRTLIALRAFREQHGSRPDFAAWLRSSQPLTQLKPLRDILSLDQLRSASSPPPTQVTPHVFHKPADTSQRSHAAKAADSSEPATTSRAPQPVSDRTEARASNQSLNPSRDEEASLTETARYGVPIQPAGTTSTDDVSLTETARYGVPIQPVSPSRTAPPPRPESPRKREPVRVGETDSLLREPVVFSPDEFTRHAAFLGGSGSGKTTLALNIVEQLALQGVPTILVDRKGDLAGYASDAFWTSTVGDPRRAMRQGALRDRLDVALFTPGHPGGRPLAIPIVPDGLDALPDFDRQQATRHAAEALAGMLDYRQSPKDKSCRTLLAQAIDQYVQLTRESVSLERLVKFIGDKDPRLVNAVGRLDVKLFDKLADDLDRLRLDARMLLDGEAEKLDMDLLLGRGAHALPGRTRLSIVSTKFLGDNNNVLFWVSQLLIEVTRWLSRNPSTPLQAAMLFDEADLYLPAMRQPSTKQPMENLLKRARSGGLGLMLATQSPGDFDYKCRDNIRAWFIGRVKEKVSLDKMKPMLSEARVDPARIPGQATGEFHVARDGRVDRVKAEPSALATEQLSDDELLRLAARTRESRHLSS
>NZ_CP022098.1|WP_095983355.1|38115_39144_+|hypothetical-protein
MQGSEVSRVGELVLVWLLTQAEGKGARSKVSSALKPFTAHRWSPGEWSTQLDAALGALAAAGLIEQTARKGLGLTKEGKARALEFLGEPRLPKGLNWKKLRLTWLTARALDLPNSQGEKLGAAKHLRAVLVQKQLGLERVGARTLKQVQDELCWKQLGVTTDKPFTLAAVQSLLLGQVLQSSREVKASQALDQLAARKVGARRTDAESLRLAALQSWVLPASSPSPQATAAPAPARAPEPVPAPAPRSVDESLPDFAERVLSTARAATSGRFGDDRVFISHVWRALGDPALDESTFKNRLIEANQKRLLSLSRADMVNLMDPADVSASETRYLGATFHFIAL
>NZ_CP022098.1|WP_095983354.1|36848_38129_+|DUF559-domain-containing-protein
MPTPRPESAAPPALERHQRRREQGIPTLTVLAGPPGAALALWRRWLDARGQALCVCTSTTPEGLLREWMEALGQARPPTTDAAEHLGAAAGLHPGELASRLKGKTEHERGVLLQALLPSLAPGDVSAACRALLQLPQVVPNSTGPLDAVLAACEGDAMRALGAVHALVPGGAAPAILVSDPGTVAGWLEQAARVCARACESVPSLVVALQTERSGLEAYLRGPESHTRALVREGRVELAVPSAEELVRRMEALGVHKARALEAPLRQLAADGIPDEVLTRYGEAARKLEVADRESEAADGARSEAERFLYGVLDSLPATRGLFELNAKAEFRLRGRAVEVDFLSRRLRLAVEVDGYHHFRDPERYRRDRRKDLALQRHGYWVLRFLADDVVARFEEIRDTLLEVISIRRQGLGGPPPRGEDGDAGL
>NZ_CP022098.1|WP_095983353.1|35764_36724_-|glutathione-synthase
MAALTFGFLMDPLESVRVDHDSTFALMLEAQRRGHQVRYFEQPWLRFNGSRAEARMRTVTVRREPGRHFDVLGEALQPLSELDVLFLRKDPPVDAEFIQATQMVELHNGRAPVFINNPTGIRDANEKLFGLRFPELMPETLIARDMAQLSRFVASHPAGTILKPVEGFGGQGIVFMQPGDRNLRSLLEVLTVGGRKAIVAQAYLPESRQGDKRIILVDGEPCGAVLRVPSQDDHRGNMAAGGTPVKTSLTAREREICARLKPSLQERGLYLVGIDVIGDWLTEVNVTSPTGIVEIDKLDDSNVEAKVIDLAERMAGSRR
>NZ_CP022098.1|WP_157758138.1|35246_35747_+|hypothetical-protein
MIRFPGSSVVLLALVASGCDTSQAPCRETCPDISGVYSIESTTPAGECGFSPYLLPPSVRLEQTRDGRGVLFHVIDPTTQIEVPLSGDVYAPESGEEGLLGSFRIDSRTTRLARSGSDQLVTLDVTVMGSVSQVEDRRVLTATVNTTDAASNQGCTATLSVMGESR
>NZ_CP022098.1|WP_095991716.1|34318_35116_-|methyltransferase
MSTPLPSDETLDSIGTAGVRVWQRRGGYRFTLDAVLLAAFAATEGGQVEGPLLELGAGSGVVSFLLACQFGLGPVDALELQPEVHARLARAVALNGCDGRVRPVLGDLREARTSWAPGAYAHVVSNPPFRPAHAGVRSPDDERAVSKQELTCDAAAVVAAARHSLPPGGRVSLIYPAARVAEVLGLLSAARLHPMALRFVHARAGAPATRFLVHAVRDRQRGLAVRPPLLAHGEGPGGYSPEVAALMEPPRAERPAPLWEGHGGE
>NZ_CP022098.1|WP_095983351.1|32764_34315_+|carbohydrate-esterase
MRTSVLPLPRLTPLLLAALVALSGCRPTPTEVYTEVEFDVTVPPETPVNAQIFLQGEHPAFRASARGLELFYQGGQLFSARAKLPEGQEVTFTAKMASAEEQVPLELSGRPAGSWRYAARADEEKVGFTVERWGPPGGRTGPQTVFLVTVPATTPPDDVIWLSGNQPELGNWNGAGVKLHKAMDNRYAASLSFQPGTLLAFKATRGSWETVEKDAMGQEIEDHVFRTGEDYEHVPFTVEWWADFGTMPPPQVRTGNIKYHFGVQPKDDTLRARDVIVWLPPGYEEPENASRHYPVLYMHDGQNLMDATTAAYGREWNVDETAQQLVEAGEVEPLIIVGIYNAEEERIAEYTPVPFPPNYPEAGRAAAYGRFLVEELKPFIDGEYRTRTDAASTGLAGSSLGGLVSLYLGLEYPDTFTRLGVISPSVWWADREILQRVEQYNGPTSLRIWEDIGTDEGDGPEAETVSDAEDLYQALKAKGWKDADLKYTVVQGGRHNERAWSERFGKILRFLFPSMP
>NZ_CP022098.1|WP_157758137.1|31630_32527_-|hypothetical-protein
MGSFARAQDEAPPTAAPAAEAPAAERADTLQPAPPPVEETITHCGNKDVGPSEGQLQPLGHGFYADGTRVRRGCTLLLQRPLKDRPAIPFAPDSFKPLGCGFIRYATSIYWHKPLAAGDTEEEPGGERGEVLTRLDLADAETFEVVEGCRPRDARFFYLNHTDRPALPAFIAVPRDEGAGYEELGCGFVRYAGRVFFGTRSLEGAHAPSFASVQGRLPAAECGEGMYGKDRANVWWQHEQLRGASAKVFRVPREDNPDLRVACSGKRSFVLAEAQKKPHPLCRGAKKPAKAKLVKKNK
>NZ_CP022098.1|WP_095983349.1|30212_31385_-|S8-family-serine-peptidase
MTTLSKISTSSLPSSRVRTEAPTVRAPVEDPRASAPKAAGFDARSNFVDRPTGRRPSGTETPPAALLSKTASLKSVADSKPVPLSGPPVVAVFDGGVDWNHTDLKDSMWTNPWEVAGDGLDNDGNGIEDDIHGFNVGFGSGDPLRGEGMDHGTHVAGIIAAADNGLGNTGVAAGKAQILSVGGIYDGADLLTNFERSVDYVVDMKSKGANIRAVNASFGDEYRDAASQKRWKDAVQKLADADILLVAATANGNGSNMNNVKDFPANLDLPNVLTVASMDKRNDKLARYSSHGDKVVEMAAVGEDVLSTVPGGDWEEMSGTSMATPRVAATAALMFAENPKLTAAEVRDMLVATTEKDPDLKGKVSSGGKLDIDAAVAAARASAGRVAQAA
>NZ_CP022098.1|WP_157758136.1|29148_30126_-|DUF3396-domain-containing-protein
MSHPIPRIRIYSSQSGQERLIRREVVRLVLHLPFDHHDLALSVRQALDLYLSTIGQGPEILSEWYDLETEPFPLDDDNWEIIRAVMAPPRGGRFLDDLENPQEAQRYIKNQFERAVELSGGAAGVSGYGFFYRARLPWRDPGSTVSLVSFSWPTEDLEERGPKRMRELILELASLLPFSSGHAGLAFSSTHSSTLSFGQIREEAFRHPGIDVTHGSTSLGRRIDGVHWINLLGQSLLGEVGGIGGLQDRLYSPGTHVQEMDGGRAVVTLGQWPKAGDTSRGDSLPDYRELARALEPWLSTWSEDYALVGASPSETQSWWRRFLDS
>NZ_CP022098.1|WP_095983358.1|45183_46038_-|SDR-family-oxidoreductase
MKNKTVIVTGANSGVGLATTVELARRGATVVMACRSAERGEAALKLARERSGSHQLELLPCDLGSLESIRAFASAARERHPVVDVLVNNAGVVSLKRETTRDGFEAQLGVNHLGHFLLTLLLLEPLKRAPQGRVVTVSSGAHRVGNIHWADPHFTRGYSVWRGYAQSKLANVLFTKGLAYRLRGTSVTANCLHPGAVGTQLGVDRDTGGGRAIMKLLSYVFITPEQGADTSVYLASSDEVSGVSGEYFYRRKPAPVSKLAEDREQIERLWFWSEKQVGELFPFP
>NZ_CP022098.1|WP_095991717.1|46216_46567_+|hypothetical-protein
MVVGVAGLLGCGSTIADITDKQSDAVNAVADSTCDRYDECGEIASGKKYTTRDECMTAEKGNWNSRWPVAECDNRINGDKLQFCLDAIAATSCTNVLDQINTALAKCPQSDVCSGD
>NZ_CP022098.1|WP_095983359.1|46686_48504_-|M4-family-metallopeptidase
MQINNKQSPIVSSSSTSTAPAAPAAPQEPVATPKGETPAATGFGAGSTFATASRPAVALSAGQVASAAASVGPLALDSQEAKNAIQKSLAHLRSTAPTAGRGLVAGGDVSSKLTPRQVFKDELGMTHVRLDRTHEGTKVFAEQVISHLDKDGKVASTTGTLSNIPNGLGSAPVKLEAKDALAIAQKQFAGTTDRAPTSERVVAQDKDGNYRAAYHVQLTKTSSLGAEERPRRMNYLVDANTGELFKSFDQMGGIEVPHAKAGPSTPTTPSTPAPGTPAGKGNDTTMYSGKVDLSTTKQANGTYTLEDKSRGGGVVTYDAKNKSTASGTTPFTDANDVWGEAGDNARNKAAVDAHYGAEMTYDFMKDVLGRNSLDGKGEKLVSYVHVNEQDGGAMVNAYWDGEKMNYGDGDGKNAGPLTTLDIAGHEIAHGLTERTAGLIYDGESGGLNESFSDIIGSGVEWYAAQKNKSVEFDWKVGEDAWTPANGTGDALRYMDDPTKDGYSVDHYSNYPKQTEVHGSSGIANNAFYLVTEGGKNRTSGLGVDGGIGMEKSQKIFGRALTTYMTPNTNFAQAREATIQAATDLYGAKSVEVQKVKDAWTAVGVK
>NZ_CP022098.1|WP_095983360.1|48892_50158_-|hypothetical-protein
MAVRIGQPVIPKQLPSDQKLREDVRKDSRDTGKPAAGKSQGKPAAGAANAKARTEGTSAGARPLLNEGTSAGAKPLGNEGTSAGAKALQSKDGMDVGGQVGHQARLDGGQGLADKQDAKSRFQQPVRTGGAHVPTQGPTVSPFREAAVASTLEQAEQEKSEETPRGDSAREAMEGRAKLRAALMDRLLAGMKDVHGRLAKFIKNPGRLGVVNLSLVLSESSLTYELWKEPSTVPERRARMAQTLGVANSLGDNYLLQALITEVHDCFEEFKASRSGKDIRQQYDEVLELYENAGVLPVMPGFDMGPMQAELKRVGLPMEKNFLQSLLVHPRILAVGLEAEDGDDPQVMVAGLPVAQLGTIVAQLRRLNPRLTNRQVLNLMILASTDLKKGMRKVLGKAEVENVQELAKQLLRLQGVELLYP
>NZ_CP022098.1|WP_095983361.1|50364_50973_-|hypothetical-protein
MAESSTPGGSPPPASSSTAPSGDTDKAQLLKQVGDMMQAIQKMMALFNGAEEPGTPASSAPGSAKAAGVDGGAIDEALGGGEFGKTLGQVIDNEFGEKLVQALKGENGEALKNKLNDSIQKLLEQQKNNKAEVAKTLLEASEKLKKLLERPRGSDLRETARMLGDVLGEALGKIQQLASVNPVRKLGETTVELLSQQGRKGT
>NZ_CP022098.1|WP_095991718.1|51085_52408_-|FHA-domain-containing-protein
MDATATLQRVAPGRVRMKLLVLSGSEAGRGYSLDQREYIVGKAPTCDIILADKTISRQHLRIEVHEEHVLAVDLDSRNGSFCEGLRFSQMELRPGSVITLGTTELKVVPEDTRERSMPLSGRDHFGALVGTSRKMREVFTLLERMAPGGSDVLIQGETGTGKELCAEALHNESKRAKGPFIIVDLAGIAPSLIESELFGHVKGAFTGAQTDRAGAFERAAGGTVFLDEVGELPLDLQPRLLRVLERRQVKRVGANDYRTVDMRVVAATHVDLEGAVKANKFRRDLYHRLAVLRVTLPALRERPEDIPLLIDTVLGRMGKPPSALSDQTRALLSQYPWPGNVRELRNVVEQVVNLGEEALPELPPLGAGAEQAMGASTAELDLPFKEAKERLIEGFERDYLKGLLERCEGNISRASREAGIDRVYLRKLLRKHGLEDRDGG
>NZ_CP022098.1|WP_095983362.1|52505_55271_-|serine/threonine-protein-kinase
MGDGKTRSSRFRSKHSREQPAPNTGRSNRDAQVEDAPPVAQVGRYVLLKQLGQGGMGVVYSAYDPDLDRKVALKLLQSDGHSDAEAARARLLREAQAMARVTHPNVVPIHDVGMWGEHVFLAMEMADEGTLSGWLEKERPWREVLEVFLEAGRGLLAAHEAGLVHRDFKPANVLIGRGGRVYVTDFGLARKMGESVVPEEPLPEQAQGLVPPERRMLETTLTRSGVVMGTPNYMSPEQYEGGELDARSDQFSFCVALYWGLYRKRAFDSTRMRAFITSRRREELVSARTQTLDVAPAPVVKRSPAADLIQEPPRESKVPTWVRQALMRGMSLDPQERFASMRELLEALSQERRRVQRQRWAAAACAAGVGLSVVGGVVYRQSQVCTGADALMAEVWGPDSGATLDKAFQATGRPGAGEMATRVARVLEEYAADWKRQSTEACEATRVRGVQTEELLSQRVVCLDRRRQDMRAVVGVLADADAKLVDRALDAVFALPSLSECADVESLAAQQRLPVDPARRAEIARLGGELAGVKAMLDAGRYRPALEKGFSLETPVLATGHLPLIAELRYDLGALQSNLGAAAESGRLLTQAFFDAESGRADRLKVSIATRLNFVENGQKHFPQADSWAGLGEATLRRLGGDPALEADLLTNRANSAITQEHYADARTLLEKARALQEKALPPGHPKRARTLFQLGRVLLDMNERPRAVALLEEALRQTQAAVGPLHPDTGRRHGLLAGLLLEMGQPERALEHARAVVAAHTAAFGEHSPQVASALDGVGQCLLKLGRSEESLATFERALALKREALAPDDEDLQYSYDGVGQALMRLGRTREAIEPLRRAVAFPTMSPDALAESGYALARALWATDPGPEARGEARREAAQARERFLQAGLAPRASEVDSWLESLPQESSSLALRRSVRR
>NZ_CP022098.1|WP_095983363.1|55353_57354_-|GAF-domain-containing-protein
MATPESHAVTSGARERASAAAWGSRWPRSGNRLGRRLLLYILLFSTAVSLLGTLVQLGTDYQREVRQLEERFRQIRSSHTQGLAESLWTLDETLLRTQLEGITTLPGIVLAEVDTELGTHYVAGGGEPREFSHDFPLYHGARLLGTLRVGANLAHARAELRSRVLVILATEAGKTFLFGLFAFFLIQRLVTQHLATMAAYARGLDTQHLEAPLVLRRTGTHRVRQDELDEVSAAINEMRESLRKELEERQRSEAASAFLSRAGAVLVESLDLEKVLPRIAFVCVGPLADWCVIDLREDGVLRRVGGAHVDVAKTPLLDELQRRYPLGPDSRVPAAVAMRTGTWVLESRVTRAGLRAWCVDDAHVQLVSELGLGSVLAVPLMSRGHALGAITFAAAGPERYGPAELALAEELARRTAIAIDNARLYRQAEQALRLRETFLSVAGHELRTPLLPLQLRLQSLLRRGRNAAPLEPEVLLGEIAVAEWQTRRLGLLVDQLLDVSHLIAGNALVLRRKRMDLCKLVEGVLEGVQRQISDSGSEVVRELCSPVEGEWDPRRLELVVMGLVQNALKFGEGRPIDVRVTPREGSVVLVVRDRGMGMSKSEQEHIFDRFSRGVPEQHFGGLGLGLYLTREVVRAHSGSISVESAPGQGTTFTVVLPLGEAPGPVA
>NZ_CP022098.1|WP_095983364.1|57340_58537_-|substrate-binding-domain-containing-protein
MTTLRWRLGALLAPVLLPLLLLVLILLGAAPPEPAAPARARMRVVFLNALGIGGGFSRQFRGAMHAAAHDLGIELIDIDVGHWPGQILEQARQAVSGPDKPDYLITSIHRGIGARVLEVAEQAQVPVFVVNSGLALEERARFGGPREHFTWWVGQMVPDDVGAGERLVRLLIDAAQARRRSLERGPVEGPVRLIAIEGQWGDTSAKQRHLGLRQALSGEKDAELLQSVTAAWQREESRRKTFLLLRRYPELEVIWAANDDLAMGAVQALEEAGRRPGEDVQVGGIDWTPEALQAVREGKLVTSLGGHFLEGAWALVLLYDHHQGRDFASERLDWRTAFLPATRANAAGYLEVLARPDWEAFDFRAFSKAVNPRLTHYDFSLQALFAQRHRRMDPNGNP
>NZ_CP022098.1|WP_095983365.1|58824_59751_+|hypothetical-protein
MSLTIPPNSVTLPRVTKSSTTEPETQTPPPPPPKLTKELETVKDDYQQALENQKQWLIKYGAPKEQIEALDKAIEQHQESVLDLNNARNSQNNVVALEQKDAGGWNSEAPVLQQEGNSDCGETVAAMFKGAKEGREKVEGERGQGVINDFKSRFTKGDGTTPAEMADMLTSEGLEVKHSTKGLERNVMDEALRNGDKAAVMLDSKISGSPDDASGSPHWVLIDGMDNQGRYLVKDPSNGSSYYAKPEDLANAIDTNQSKSHSGGVLIVGNPDVPTDLAGKNRDNAETLGDKPGKGWGWKNNSQESSDG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_2

49903-49997

Orphan

Consensus_repeat	Method
TGGCGCCCGCGCTGGTGCCCTCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022098_2

>merge|NZ_CP022098|2|49903-49997|CRISPRCasFinder
TGGCGCCCGCGCTGGTGCCCTCGTTGCCGAGGGGCTTGGCGCCCGCGCTGGTGCCCTCGTTGAGCAGGGGCCTGGCGCCCGCGCTGGTGCCCTCG

>NZ_CP022098|2|2|49903-49997|CRISPRCasFinder
TGGCGCCCGCGCTGGTGCCCTCG	TTGCCGAGGGGCTTGGCGCCCGCGCTGGTGCCCTCGTTGAGCAGGGGCC
TGGCGCCCGCGCTGGTGCCCTCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_095983364.1\|57340_58537_-\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|380547
NZ_CP022098.1\|WP_095983356.1\|39181_42586_+\|DUF853-family-protein	unknown	unknown	gnl\|CDD\|223510
NZ_CP022098.1\|WP_157758139.1\|61831_62119_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095991717.1\|46216_46567_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095983365.1\|58824_59751_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234609
NZ_CP022098.1\|WP_095991716.1\|34318_35116_-\|methyltransferase	unknown	unknown	gnl\|CDD\|226608
NZ_CP022098.1\|WP_095983354.1\|36848_38129_+\|DUF559-domain-containing-protein	unknown	unknown	gnl\|CDD\|238509
NZ_CP022098.1\|WP_095983369.1\|63620_64220_-\|DUF938-domain-containing-protein	unknown	unknown	gnl\|CDD\|253548
NZ_CP022098.1\|WP_095983355.1\|38115_39144_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236999
NZ_CP022098.1\|WP_095983358.1\|45183_46038_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212492
NZ_CP022098.1\|WP_095983366.1\|59772_61542_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP022098.1\|WP_095983362.1\|52505_55271_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP022098.1\|WP_095983353.1\|35764_36724_-\|glutathione-synthase	unknown	unknown	gnl\|CDD\|235371
NZ_CP022098.1\|WP_095991718.1\|51085_52408_-\|FHA-domain-containing-protein	unknown	unknown	gnl\|CDD\|225114
NZ_CP022098.1\|WP_095983357.1\|42683_44729_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_157758138.1\|35246_35747_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095983368.1\|62582_63617_+\|squalene/phytoene-synthase-family-protein	unknown	unknown	gnl\|CDD\|173831
NZ_CP022098.1\|WP_095983363.1\|55353_57354_-\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|223715
NZ_CP022098.1\|WP_095983359.1\|46686_48504_-\|M4-family-metallopeptidase	unknown	unknown	gnl\|CDD\|341060
NZ_CP022098.1\|WP_095983361.1\|50364_50973_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095983356.1\|39181_42586_+\|DUF853-family-protein	gnl\|CDD\|223510	COG0433, COG0433, HerA helicase [Replication, recombination, and repair].	3.84058e-08
NZ_CP022098.1\|WP_095991716.1\|34318_35116_-\|methyltransferase	gnl\|CDD\|226608	COG4123, COG4123, Predicted O-methyltransferase [General function prediction only].	3.45064e-52
NZ_CP022098.1\|WP_095983365.1\|58824_59751_+\|hypothetical-protein	gnl\|CDD\|234609	PRK00068, PRK00068, hypothetical protein; Validated.	0.00633414
NZ_CP022098.1\|WP_095983364.1\|57340_58537_-\|substrate-binding-domain-containing-protein	gnl\|CDD\|380547	cd06324, PBP1_ABC_sugar_binding-like, periplasmic sugar-binding domain of uncharacterized ABC-type transport systems. This group includes the periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.	2.05191e-121
NZ_CP022098.1\|WP_095983354.1\|36848_38129_+\|DUF559-domain-containing-protein	gnl\|CDD\|238509	cd01038, Endonuclease_DUF559, Domain of unknown function, appears to be related to a diverse group of endonucleases.	4.89323e-09
NZ_CP022098.1\|WP_095983369.1\|63620_64220_-\|DUF938-domain-containing-protein	gnl\|CDD\|253548	pfam06080, DUF938, Protein of unknown function (DUF938). This family consists of several hypothetical proteins from both prokaryotes and eukaryotes. The function of this family is unknown.	2.31328e-77
NZ_CP022098.1\|WP_095983355.1\|38115_39144_+\|hypothetical-protein	gnl\|CDD\|236999	PRK11854, aceF, pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated.	0.000519172
NZ_CP022098.1\|WP_095983358.1\|45183_46038_-\|SDR-family-oxidoreductase	gnl\|CDD\|212492	cd05327, retinol-DH_like_SDR_c_like, retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs. Classical SDR subgroup containing retinol-DHs, LPORs, and related proteins. Retinol is processed by a medium chain alcohol dehydrogenase followed by retinol-DHs. Pchlide reductases act in chlorophyll biosynthesis. There are distinct enzymes that catalyze Pchlide reduction in light or dark conditions. Light-dependent reduction is via an NADP-dependent SDR, LPOR. Proteins in this subfamily share the glycine-rich NAD-binding motif of the classical SDRs, have a partial match to the canonical active site tetrad, but lack the typical active site Ser. This subgroup includes the human proteins: retinol dehydrogenase -12, -13 ,and -14, dehydrogenase/reductase SDR family member (DHRS)-12 , -13 and -X (a DHRS on chromosome X), and WWOX (WW domain-containing oxidoreductase), as well as a Neurospora crassa SDR encoded by the blue light inducible bli-4 gene. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	4.81148e-110
NZ_CP022098.1\|WP_095983366.1\|59772_61542_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.57264e-87
NZ_CP022098.1\|WP_095983362.1\|52505_55271_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.03522e-81
NZ_CP022098.1\|WP_095983353.1\|35764_36724_-\|glutathione-synthase	gnl\|CDD\|235371	PRK05246, PRK05246, glutathione synthetase; Provisional.	8.96513e-155
NZ_CP022098.1\|WP_095991718.1\|51085_52408_-\|FHA-domain-containing-protein	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	2.58423e-117
NZ_CP022098.1\|WP_095983363.1\|55353_57354_-\|GAF-domain-containing-protein	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.43642e-44
NZ_CP022098.1\|WP_095983359.1\|46686_48504_-\|M4-family-metallopeptidase	gnl\|CDD\|341060	cd09597, M4_TLP, Peptidase M4 family including thermolysin, protealysin, aureolysin, and neutral protease. This peptidase M4 family includes several endopeptidases such as thermolysin (EC 3.4.24.27), aureolysin (the extracellular metalloproteinase from Staphylococcus aureus), neutral protease from Bacillus cereus, protealysin, and bacillolysin (EC 3.4.24.28). Typically, the M4 peptidases consist of a presequence (signal sequence), a propeptide sequence, and a peptidase unit. The presequence is cleaved off during export while the propeptide has inhibitory and chaperone functions and facilitates folding. The propeptide remains attached until the peptidase is secreted and can be safely activated. All peptidases in this family bind a single catalytic zinc ion which is tetrahedrally co-ordinated by three amino acid ligands and a water molecule that forms the nucleophile on activation during catalysis. The active site is found between two sub-domains; the N-terminal domain contains the HEXXH zinc-binding motif while the helical C-terminal domain, which is unique for the family, carries the third zinc ligand. These peptidases are secreted eubacterial endopeptidases from Gram-positive or Gram-negative sources that degrade extracellular proteins and peptides for bacterial nutrition. They are selectively inhibited by Steptomyces metalloproteinase inhibitor (SMPI) as well as by phosphoramidon from Streptomyces tanashiensis. A large number of these enzymes are implicated as key factors in the pathogenesis of various diseases, including gastritis, peptic ulcer, gastric carcinoma, cholera and several types of bacterial infections, and are therefore important drug targets. Some enzymes of the family can function at extremes of temperatures, while some function in organic solvents, thus rendering them novel targets for biotechnological applications. Thermolysin is widely used as a nonspecific protease to obtain fragments for peptide sequencing. It has also been used in production of the artificial sweetener aspartame.	1.56753e-119
NZ_CP022098.1\|WP_095983368.1\|62582_63617_+\|squalene/phytoene-synthase-family-protein	gnl\|CDD\|173831	cd00683, Trans_IPPS_HH, Trans-Isoprenyl Diphosphate Synthases, head-to-head. These trans-Isoprenyl Diphosphate Synthases (Trans_IPPS) catalyze a head-to-head (HH) (1'-1) condensation reaction. This CD includes squalene and phytoene synthases which catalyze the 1'-1 condensation of two 15-carbon (farnesyl) and 20-carbon (geranylgeranyl) isoprenyl diphosphates, respectively. The catalytic site consists of a large central cavity formed by mostly antiparallel alpha helices with two aspartate-rich regions (DXXXD) located on opposite walls. These residues mediate binding of prenyl phosphates. A two-step reaction has been proposed for squalene synthase (farnesyl-diphosphate farnesyltransferase) in which, two molecules of FPP react to form a stable cyclopropylcarbinyl diphosphate intermediate, and then the intermediate undergoes heterolysis, isomerization, and reduction with NADPH to form squalene, a precursor of cholestrol. The carotenoid biosynthesis enzyme, phytoene synthase (CrtB), catalyzes the condensation reaction of two molecules of geranylgeranyl diphosphate to produce phytoene, a precursor of beta-carotene. These enzymes produce the triterpene and tetraterpene precursors for many diverse sterol and carotenoid end products and are widely distributed among eukareya, bacteria, and archaea.	8.63977e-50

>NZ_CP022098.1|WP_095983359.1|46686_48504_-|M4-family-metallopeptidase
MQINNKQSPIVSSSSTSTAPAAPAAPQEPVATPKGETPAATGFGAGSTFATASRPAVALSAGQVASAAASVGPLALDSQEAKNAIQKSLAHLRSTAPTAGRGLVAGGDVSSKLTPRQVFKDELGMTHVRLDRTHEGTKVFAEQVISHLDKDGKVASTTGTLSNIPNGLGSAPVKLEAKDALAIAQKQFAGTTDRAPTSERVVAQDKDGNYRAAYHVQLTKTSSLGAEERPRRMNYLVDANTGELFKSFDQMGGIEVPHAKAGPSTPTTPSTPAPGTPAGKGNDTTMYSGKVDLSTTKQANGTYTLEDKSRGGGVVTYDAKNKSTASGTTPFTDANDVWGEAGDNARNKAAVDAHYGAEMTYDFMKDVLGRNSLDGKGEKLVSYVHVNEQDGGAMVNAYWDGEKMNYGDGDGKNAGPLTTLDIAGHEIAHGLTERTAGLIYDGESGGLNESFSDIIGSGVEWYAAQKNKSVEFDWKVGEDAWTPANGTGDALRYMDDPTKDGYSVDHYSNYPKQTEVHGSSGIANNAFYLVTEGGKNRTSGLGVDGGIGMEKSQKIFGRALTTYMTPNTNFAQAREATIQAATDLYGAKSVEVQKVKDAWTAVGVK
>NZ_CP022098.1|WP_095991717.1|46216_46567_+|hypothetical-protein
MVVGVAGLLGCGSTIADITDKQSDAVNAVADSTCDRYDECGEIASGKKYTTRDECMTAEKGNWNSRWPVAECDNRINGDKLQFCLDAIAATSCTNVLDQINTALAKCPQSDVCSGD
>NZ_CP022098.1|WP_095983358.1|45183_46038_-|SDR-family-oxidoreductase
MKNKTVIVTGANSGVGLATTVELARRGATVVMACRSAERGEAALKLARERSGSHQLELLPCDLGSLESIRAFASAARERHPVVDVLVNNAGVVSLKRETTRDGFEAQLGVNHLGHFLLTLLLLEPLKRAPQGRVVTVSSGAHRVGNIHWADPHFTRGYSVWRGYAQSKLANVLFTKGLAYRLRGTSVTANCLHPGAVGTQLGVDRDTGGGRAIMKLLSYVFITPEQGADTSVYLASSDEVSGVSGEYFYRRKPAPVSKLAEDREQIERLWFWSEKQVGELFPFP
>NZ_CP022098.1|WP_095983357.1|42683_44729_-|hypothetical-protein
MTTITRTTQTTTTTTVSNDLPNPAQATQVAAQLAQAINQLGQALTAATQQTGAALPKDGMMQAQSQAPVNLSGSAAPGGMDVYKAAAALDKHFAVAEGIGTNGKGKGSGDGNIGLGELKNLANPANGAPPELQQAAQFLLSHPSMAKVIDGAKGKGGDVHINRADLQKMMAGAPAGSLPGPVSNDLAPKMSAAMASLLGASPTAGNIPTSAPTTAMSPATASGTFASPTQGAPMDVYGAAQALKNHFAVAEGIGTNGKGKGSGDGNIGLGELKQLANPASGAPAQLQQAAQFLLAHPAMAKVLDGAKGKGGDVHINMADLNKLLANAPAGSGAGPSAAQSQLQNLLGNAPAPTANAQSQLQNLQNMAQTLSSAMASLLGSSPISGSAPMQQPMGASGTAAPGGMDVYKAASALDKHFAVAEGIGMNGKGKGSGDGNIGLSELKNLANPKSGAPAELQQAAQFLLAHPAMAKVIDGAKGKGGDVHINRADLQKMMASAPASTASMPTAPVSTQGAQGGNSLMNIFNQAAGTASPTTAMSPATASGTFASPTQAKPMDVYGAAQELKNHFAVAEGIGMNGKGKGSGDGNIGLSELKQLANPASGAPPRLQQAAQFMLAHPSMAKVIDGAKGKGGDVHINMADLNKILSSAPGGSGGTQGVAGTSAKDIIMEQVKATAFKMNIS
>NZ_CP022098.1|WP_095983356.1|39181_42586_+|DUF853-family-protein
MNPHDSRLAAFLSDRTEVFHSIQHRHEVWREDPFDVESIHQDARATFERMLQRATTPPGTPSGRILLLLGDSGCGKTHLLRTFRSLVHERSLGFVGYLQMTTSTSNYGRYVLSNLIDSLDQPYCEPGEPRSGLRKLSDVLLSQCGPVAALLADPEQDPEEIPVLVESAADDLQKQPAFEKLDLDLLRALLYLQRDDTRIRSRVLKYLRCEDLSTSDRKVLGGMVPRTYDNHPQEMVQHLGRLMATLNQSLVLCVDQLEGFDVEAAQAQAFQRAMHLLCDFAESAPSSLIVISCLHTFWTGLREKLHRSTLDRIERDPEPLKLENQRSVDEARRITERRLEHLYSMEDAPFDPAEPTYPFPHEGFERLAGLTTREVLDACRRWREQAVRDQALPAQFPLRDAPKETRPPPNETKKLLALDQAWNDFRSTQATPPPEEDGPLAELLVWALKAIADELETGHRFDVRRLGEVLQVDVSPGDEKLHVALCNRGTQGGGLANQIEQTRKEARGRTPVVIRTSDFPSNPKTQAAAELGKLLSKGGRRAVLEDSDSRTLIALRAFREQHGSRPDFAAWLRSSQPLTQLKPLRDILSLDQLRSASSPPPTQVTPHVFHKPADTSQRSHAAKAADSSEPATTSRAPQPVSDRTEARASNQSLNPSRDEEASLTETARYGVPIQPAGTTSTDDVSLTETARYGVPIQPVSPSRTAPPPRPESPRKREPVRVGETDSLLREPVVFSPDEFTRHAAFLGGSGSGKTTLALNIVEQLALQGVPTILVDRKGDLAGYASDAFWTSTVGDPRRAMRQGALRDRLDVALFTPGHPGGRPLAIPIVPDGLDALPDFDRQQATRHAAEALAGMLDYRQSPKDKSCRTLLAQAIDQYVQLTRESVSLERLVKFIGDKDPRLVNAVGRLDVKLFDKLADDLDRLRLDARMLLDGEAEKLDMDLLLGRGAHALPGRTRLSIVSTKFLGDNNNVLFWVSQLLIEVTRWLSRNPSTPLQAAMLFDEADLYLPAMRQPSTKQPMENLLKRARSGGLGLMLATQSPGDFDYKCRDNIRAWFIGRVKEKVSLDKMKPMLSEARVDPARIPGQATGEFHVARDGRVDRVKAEPSALATEQLSDDELLRLAARTRESRHLSS
>NZ_CP022098.1|WP_095983355.1|38115_39144_+|hypothetical-protein
MQGSEVSRVGELVLVWLLTQAEGKGARSKVSSALKPFTAHRWSPGEWSTQLDAALGALAAAGLIEQTARKGLGLTKEGKARALEFLGEPRLPKGLNWKKLRLTWLTARALDLPNSQGEKLGAAKHLRAVLVQKQLGLERVGARTLKQVQDELCWKQLGVTTDKPFTLAAVQSLLLGQVLQSSREVKASQALDQLAARKVGARRTDAESLRLAALQSWVLPASSPSPQATAAPAPARAPEPVPAPAPRSVDESLPDFAERVLSTARAATSGRFGDDRVFISHVWRALGDPALDESTFKNRLIEANQKRLLSLSRADMVNLMDPADVSASETRYLGATFHFIAL
>NZ_CP022098.1|WP_095983354.1|36848_38129_+|DUF559-domain-containing-protein
MPTPRPESAAPPALERHQRRREQGIPTLTVLAGPPGAALALWRRWLDARGQALCVCTSTTPEGLLREWMEALGQARPPTTDAAEHLGAAAGLHPGELASRLKGKTEHERGVLLQALLPSLAPGDVSAACRALLQLPQVVPNSTGPLDAVLAACEGDAMRALGAVHALVPGGAAPAILVSDPGTVAGWLEQAARVCARACESVPSLVVALQTERSGLEAYLRGPESHTRALVREGRVELAVPSAEELVRRMEALGVHKARALEAPLRQLAADGIPDEVLTRYGEAARKLEVADRESEAADGARSEAERFLYGVLDSLPATRGLFELNAKAEFRLRGRAVEVDFLSRRLRLAVEVDGYHHFRDPERYRRDRRKDLALQRHGYWVLRFLADDVVARFEEIRDTLLEVISIRRQGLGGPPPRGEDGDAGL
>NZ_CP022098.1|WP_095983353.1|35764_36724_-|glutathione-synthase
MAALTFGFLMDPLESVRVDHDSTFALMLEAQRRGHQVRYFEQPWLRFNGSRAEARMRTVTVRREPGRHFDVLGEALQPLSELDVLFLRKDPPVDAEFIQATQMVELHNGRAPVFINNPTGIRDANEKLFGLRFPELMPETLIARDMAQLSRFVASHPAGTILKPVEGFGGQGIVFMQPGDRNLRSLLEVLTVGGRKAIVAQAYLPESRQGDKRIILVDGEPCGAVLRVPSQDDHRGNMAAGGTPVKTSLTAREREICARLKPSLQERGLYLVGIDVIGDWLTEVNVTSPTGIVEIDKLDDSNVEAKVIDLAERMAGSRR
>NZ_CP022098.1|WP_157758138.1|35246_35747_+|hypothetical-protein
MIRFPGSSVVLLALVASGCDTSQAPCRETCPDISGVYSIESTTPAGECGFSPYLLPPSVRLEQTRDGRGVLFHVIDPTTQIEVPLSGDVYAPESGEEGLLGSFRIDSRTTRLARSGSDQLVTLDVTVMGSVSQVEDRRVLTATVNTTDAASNQGCTATLSVMGESR
>NZ_CP022098.1|WP_095991716.1|34318_35116_-|methyltransferase
MSTPLPSDETLDSIGTAGVRVWQRRGGYRFTLDAVLLAAFAATEGGQVEGPLLELGAGSGVVSFLLACQFGLGPVDALELQPEVHARLARAVALNGCDGRVRPVLGDLREARTSWAPGAYAHVVSNPPFRPAHAGVRSPDDERAVSKQELTCDAAAVVAAARHSLPPGGRVSLIYPAARVAEVLGLLSAARLHPMALRFVHARAGAPATRFLVHAVRDRQRGLAVRPPLLAHGEGPGGYSPEVAALMEPPRAERPAPLWEGHGGE
>NZ_CP022098.1|WP_095983361.1|50364_50973_-|hypothetical-protein
MAESSTPGGSPPPASSSTAPSGDTDKAQLLKQVGDMMQAIQKMMALFNGAEEPGTPASSAPGSAKAAGVDGGAIDEALGGGEFGKTLGQVIDNEFGEKLVQALKGENGEALKNKLNDSIQKLLEQQKNNKAEVAKTLLEASEKLKKLLERPRGSDLRETARMLGDVLGEALGKIQQLASVNPVRKLGETTVELLSQQGRKGT
>NZ_CP022098.1|WP_095991718.1|51085_52408_-|FHA-domain-containing-protein
MDATATLQRVAPGRVRMKLLVLSGSEAGRGYSLDQREYIVGKAPTCDIILADKTISRQHLRIEVHEEHVLAVDLDSRNGSFCEGLRFSQMELRPGSVITLGTTELKVVPEDTRERSMPLSGRDHFGALVGTSRKMREVFTLLERMAPGGSDVLIQGETGTGKELCAEALHNESKRAKGPFIIVDLAGIAPSLIESELFGHVKGAFTGAQTDRAGAFERAAGGTVFLDEVGELPLDLQPRLLRVLERRQVKRVGANDYRTVDMRVVAATHVDLEGAVKANKFRRDLYHRLAVLRVTLPALRERPEDIPLLIDTVLGRMGKPPSALSDQTRALLSQYPWPGNVRELRNVVEQVVNLGEEALPELPPLGAGAEQAMGASTAELDLPFKEAKERLIEGFERDYLKGLLERCEGNISRASREAGIDRVYLRKLLRKHGLEDRDGG
>NZ_CP022098.1|WP_095983362.1|52505_55271_-|serine/threonine-protein-kinase
MGDGKTRSSRFRSKHSREQPAPNTGRSNRDAQVEDAPPVAQVGRYVLLKQLGQGGMGVVYSAYDPDLDRKVALKLLQSDGHSDAEAARARLLREAQAMARVTHPNVVPIHDVGMWGEHVFLAMEMADEGTLSGWLEKERPWREVLEVFLEAGRGLLAAHEAGLVHRDFKPANVLIGRGGRVYVTDFGLARKMGESVVPEEPLPEQAQGLVPPERRMLETTLTRSGVVMGTPNYMSPEQYEGGELDARSDQFSFCVALYWGLYRKRAFDSTRMRAFITSRRREELVSARTQTLDVAPAPVVKRSPAADLIQEPPRESKVPTWVRQALMRGMSLDPQERFASMRELLEALSQERRRVQRQRWAAAACAAGVGLSVVGGVVYRQSQVCTGADALMAEVWGPDSGATLDKAFQATGRPGAGEMATRVARVLEEYAADWKRQSTEACEATRVRGVQTEELLSQRVVCLDRRRQDMRAVVGVLADADAKLVDRALDAVFALPSLSECADVESLAAQQRLPVDPARRAEIARLGGELAGVKAMLDAGRYRPALEKGFSLETPVLATGHLPLIAELRYDLGALQSNLGAAAESGRLLTQAFFDAESGRADRLKVSIATRLNFVENGQKHFPQADSWAGLGEATLRRLGGDPALEADLLTNRANSAITQEHYADARTLLEKARALQEKALPPGHPKRARTLFQLGRVLLDMNERPRAVALLEEALRQTQAAVGPLHPDTGRRHGLLAGLLLEMGQPERALEHARAVVAAHTAAFGEHSPQVASALDGVGQCLLKLGRSEESLATFERALALKREALAPDDEDLQYSYDGVGQALMRLGRTREAIEPLRRAVAFPTMSPDALAESGYALARALWATDPGPEARGEARREAAQARERFLQAGLAPRASEVDSWLESLPQESSSLALRRSVRR
>NZ_CP022098.1|WP_095983363.1|55353_57354_-|GAF-domain-containing-protein
MATPESHAVTSGARERASAAAWGSRWPRSGNRLGRRLLLYILLFSTAVSLLGTLVQLGTDYQREVRQLEERFRQIRSSHTQGLAESLWTLDETLLRTQLEGITTLPGIVLAEVDTELGTHYVAGGGEPREFSHDFPLYHGARLLGTLRVGANLAHARAELRSRVLVILATEAGKTFLFGLFAFFLIQRLVTQHLATMAAYARGLDTQHLEAPLVLRRTGTHRVRQDELDEVSAAINEMRESLRKELEERQRSEAASAFLSRAGAVLVESLDLEKVLPRIAFVCVGPLADWCVIDLREDGVLRRVGGAHVDVAKTPLLDELQRRYPLGPDSRVPAAVAMRTGTWVLESRVTRAGLRAWCVDDAHVQLVSELGLGSVLAVPLMSRGHALGAITFAAAGPERYGPAELALAEELARRTAIAIDNARLYRQAEQALRLRETFLSVAGHELRTPLLPLQLRLQSLLRRGRNAAPLEPEVLLGEIAVAEWQTRRLGLLVDQLLDVSHLIAGNALVLRRKRMDLCKLVEGVLEGVQRQISDSGSEVVRELCSPVEGEWDPRRLELVVMGLVQNALKFGEGRPIDVRVTPREGSVVLVVRDRGMGMSKSEQEHIFDRFSRGVPEQHFGGLGLGLYLTREVVRAHSGSISVESAPGQGTTFTVVLPLGEAPGPVA
>NZ_CP022098.1|WP_095983364.1|57340_58537_-|substrate-binding-domain-containing-protein
MTTLRWRLGALLAPVLLPLLLLVLILLGAAPPEPAAPARARMRVVFLNALGIGGGFSRQFRGAMHAAAHDLGIELIDIDVGHWPGQILEQARQAVSGPDKPDYLITSIHRGIGARVLEVAEQAQVPVFVVNSGLALEERARFGGPREHFTWWVGQMVPDDVGAGERLVRLLIDAAQARRRSLERGPVEGPVRLIAIEGQWGDTSAKQRHLGLRQALSGEKDAELLQSVTAAWQREESRRKTFLLLRRYPELEVIWAANDDLAMGAVQALEEAGRRPGEDVQVGGIDWTPEALQAVREGKLVTSLGGHFLEGAWALVLLYDHHQGRDFASERLDWRTAFLPATRANAAGYLEVLARPDWEAFDFRAFSKAVNPRLTHYDFSLQALFAQRHRRMDPNGNP
>NZ_CP022098.1|WP_095983365.1|58824_59751_+|hypothetical-protein
MSLTIPPNSVTLPRVTKSSTTEPETQTPPPPPPKLTKELETVKDDYQQALENQKQWLIKYGAPKEQIEALDKAIEQHQESVLDLNNARNSQNNVVALEQKDAGGWNSEAPVLQQEGNSDCGETVAAMFKGAKEGREKVEGERGQGVINDFKSRFTKGDGTTPAEMADMLTSEGLEVKHSTKGLERNVMDEALRNGDKAAVMLDSKISGSPDDASGSPHWVLIDGMDNQGRYLVKDPSNGSSYYAKPEDLANAIDTNQSKSHSGGVLIVGNPDVPTDLAGKNRDNAETLGDKPGKGWGWKNNSQESSDG
>NZ_CP022098.1|WP_095983366.1|59772_61542_-|serine/threonine-protein-kinase
MSDPAQGPSASSSPVPFDPHRGERIGRYEVLSQLSVGGMAELFLGYTSGPGGFRKYAAIKRILPDARSDEQFERMFLDEARITAAFSHPNIGQVFELGQDQGGLFLAMEFIAGQNLDQVIALGRRLGGTLPLGFVLSVVRDVCLALHYAHTFTTPGGKPHPVIHRDVAHKNVMVTYDGMVKLLDFGIAKARGARANTQAGMVKGTTGYMSPEQVRGQPLDGRSDLFSVGVMLHELLTGERLFAAGSEIQEMQMILGASIPDPQPRGGQVSAEIRAVALKALARDREQRYATGRDMARALEAAAGPLLFDAEQRAAFMAEHFQKQREGTRQLLQTVDETLDGTSKVAPIASRPEPEPARALEDVRRPGVEKRPVPRRKTEPEVPATPPDRVVTTGRVVTREFSNAPAAPPDTRETPGLKVAKSSLGLWAGMLVLGGLLGLGAMELRQVFLAEPIPAPPPGSAEDPSPLLPLGPSRPQGPVPLPETAAEPTSPPAEEASKASASTAEATGAASPARPAKQGLLTLVTRPEAEVFLNGRSLGKTPLFKKPVPVGQLRLLLQGQDGKRRELFVPIEQGKPAVLNLTLADLPVR
>NZ_CP022098.1|WP_157758139.1|61831_62119_-|hypothetical-protein
MAFTESVSSEQPAQAFSLYVPFPQQAQMDLLPADTRHTLLGELFQMAVQAARERDFLPRAAPVTLEFQLAGCDVRLELDAERARLTLVSLSRTWH
>NZ_CP022098.1|WP_095983368.1|62582_63617_+|squalene/phytoene-synthase-family-protein
MLNDSSALAFCREVLPAVSRTFALNIPVLPAPLDTAVLVAYLLCRIADTLEDEVRGPASAVLLAELARLSTLPEGWREDARRFTGEAARELRAQAPEAEVRLVEGTGFVLEALGEHAAPVREHVATCLRLMTEGMGRMGNKGRASGGGLGLDSLEETLEYCYYVAGTVGEMLTRLFEWYSPAIAGRARTLEPRSVAFGNALQLTNILKDVREDLERGFCWLPRPLLAEHGLTPEVLLEPGNRGAALEAHGRLVAVAHRELRQAFEYVLGLPREEHGIRLFCLWPLFLAVMTLRKLYGNGRVLEPGPVKVSRRTVKWVVAATKLLVARDGALKLMFAALTAPLPA
>NZ_CP022098.1|WP_095983369.1|63620_64220_-|DUF938-domain-containing-protein
MKRHAPSAERNRDPLLPVLREVLPAQGTVLELASGTGQHAVFFARALPGLTWQPTDVDPTALASIEAWRQEEGPPNLRAPLALDVLAEPWPVERADALVAINLVHISPWEACQGLLRGAGRVLAPGAPLVLYGAWFIEGQTPAPSNLAFDASLRERNPSWGVRELGAVTAEARRHGLERERVIEMPSNNLTVVFRARAG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_3

108944-109053

Orphan

Consensus_repeat	Method
TTGCAGCCGGGGCCGTGCACGTGCGGCTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022098_3

>merge|NZ_CP022098|3|108944-109053|CRISPRCasFinder
TTGCAGCCGGGGCCGTGCACGTGCGGCTTGGCCTCGTGGACATGGGCATGACCGTGGTCGTGGTCATGATCATGGTCGTGCTTGCAGCCGGGGCCGTGCACGTGGGGCTT

>NZ_CP022098|3|3|108944-109053|CRISPRCasFinder
TTGCAGCCGGGGCCGTGCACGTGCGGCTT	GGCCTCGTGGACATGGGCATGACCGTGGTCGTGGTCATGATCATGGTCGTGC
TTGCAGCCGGGGCCGTGCACGTGGGGCTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_095991721.1\|94807_96610_-\|tryptophan-synthase-alpha-chain	unknown	unknown	unknown
NZ_CP022098.1\|WP_095983394.1\|98152_98941_-\|DUSAM-domain-containing-protein	unknown	unknown	gnl\|CDD\|370553
NZ_CP022098.1\|WP_095983402.1\|105357_106224_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293828
NZ_CP022098.1\|WP_095983396.1\|99477_100263_-\|DUSAM-domain-containing-protein	unknown	unknown	gnl\|CDD\|370553
NZ_CP022098.1\|WP_157758141.1\|100624_101509_+\|DUF2381-family-protein	unknown	unknown	gnl\|CDD\|370554
NZ_CP022098.1\|WP_095983406.1\|112403_113348_-\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|214621
NZ_CP022098.1\|WP_095983407.1\|113406_114711_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235904
NZ_CP022098.1\|WP_095983398.1\|101520_102009_+\|serine/threonine-protein-kinase	unknown	unknown	unknown
NZ_CP022098.1\|WP_095983413.1\|118323_119859_+\|pilus-assembly-protein	unknown	unknown	gnl\|CDD\|227296
NZ_CP022098.1\|WP_095983393.1\|97280_98084_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_157758143.1\|104385_105207_-\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|181382
NZ_CP022098.1\|WP_095983408.1\|114761_116114_-\|RtcB-family-protein	unknown	unknown	gnl\|CDD\|376465
NZ_CP022098.1\|WP_095983405.1\|111426_112404_-\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|238119
NZ_CP022098.1\|WP_095983410.1\|116727_117099_+\|response-regulator	unknown	unknown	gnl\|CDD\|381118
NZ_CP022098.1\|WP_157758144.1\|109675_111307_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238613
NZ_CP022098.1\|WP_095983411.1\|117121_117307_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095983399.1\|102055_103393_-\|type-II-toxin-antitoxin-system-HipA-family-toxin-YjjJ	unknown	unknown	gnl\|CDD\|236623
NZ_CP022098.1\|WP_095983412.1\|117547_118345_+\|pilus-assembly-protein	unknown	unknown	gnl\|CDD\|377921
NZ_CP022098.1\|WP_157758142.1\|103510_104356_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|378820
NZ_CP022098.1\|WP_095983409.1\|116319_116613_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095983394.1\|98152_98941_-\|DUSAM-domain-containing-protein	gnl\|CDD\|370553	pfam09543, DUF2379, Protein of unknown function (DUF2379). This family consists of at least 7 paralogs in Myxococcus xanthus and 6 in Stigmatella aurantiaca, both members of the Deltaproteobacteria. The function is unknown.	6.988e-46
NZ_CP022098.1\|WP_095983402.1\|105357_106224_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293828	cd07742, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	1.52891e-121
NZ_CP022098.1\|WP_095983396.1\|99477_100263_-\|DUSAM-domain-containing-protein	gnl\|CDD\|370553	pfam09543, DUF2379, Protein of unknown function (DUF2379). This family consists of at least 7 paralogs in Myxococcus xanthus and 6 in Stigmatella aurantiaca, both members of the Deltaproteobacteria. The function is unknown.	7.75158e-44
NZ_CP022098.1\|WP_157758141.1\|100624_101509_+\|DUF2381-family-protein	gnl\|CDD\|370554	pfam09544, DUF2381, Protein of unknown function (DUF2381). This family consists of at least 8 paralogs in Myxococcus xanthus, a member of the Deltaproteobacteria. The function is unknown.	5.43506e-43
NZ_CP022098.1\|WP_095983406.1\|112403_113348_-\|VWA-domain-containing-protein	gnl\|CDD\|214621	smart00327, VWA, von Willebrand factor (vWF) type A domain. VWA domains in extracellular eukaryotic proteins mediate adhesion via metal ion-dependent adhesion sites (MIDAS). Intracellular VWA domains and homologues in prokaryotes have recently been identified. The proposed VWA domains in integrin beta subunits have recently been substantiated using sequence-based methods.	1.17634e-06
NZ_CP022098.1\|WP_095983407.1\|113406_114711_-\|hypothetical-protein	gnl\|CDD\|235904	PRK06995, flhF, flagellar biosynthesis protein FlhF.	0.000225368
NZ_CP022098.1\|WP_095983413.1\|118323_119859_+\|pilus-assembly-protein	gnl\|CDD\|227296	COG4961, TadG, Flp pilus assembly protein TadG [Intracellular trafficking and secretion].	0.00126511
NZ_CP022098.1\|WP_157758142.1\|103510_104356_-\|alpha/beta-hydrolase	gnl\|CDD\|378820	pfam12146, Hydrolase_4, Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.	3.07068e-89
NZ_CP022098.1\|WP_157758143.1\|104385_105207_-\|methyltransferase-domain-containing-protein	gnl\|CDD\|181382	PRK08317, PRK08317, hypothetical protein; Provisional.	1.59238e-70
NZ_CP022098.1\|WP_095983408.1\|114761_116114_-\|RtcB-family-protein	gnl\|CDD\|376465	pfam01139, RtcB, tRNA-splicing ligase RtcB. This family of RNA ligases (EC:6.5.1.3) join 2',3'-cyclic phosphate and 5'-OH ends. They catalyze the splicing of tRNA and may also participate in tRNA repair and recovery from stress-induced RNA damage.	8.30602e-113
NZ_CP022098.1\|WP_095983412.1\|117547_118345_+\|pilus-assembly-protein	gnl\|CDD\|377921	pfam07811, TadE, TadE-like protein. The members of this family are similar to a region of the protein product of the bacterial tadE locus. In various bacterial species, the tad locus is closely linked to flp-like genes, which encode proteins required for the production of pili involved in adherence to surfaces. It is thought that the tad loci encode proteins that act to assemble or export an Flp pilus in various bacteria. All tad loci but TadA have putative transmembrane regions, and in fact the region in question is this family has a high proportion of hydrophobic amino acid residues.	1.3451e-07
NZ_CP022098.1\|WP_095983410.1\|116727_117099_+\|response-regulator	gnl\|CDD\|381118	cd17580, REC_2_DhkD-like, second phosphoacceptor receiver (REC) domain of Dictyostelium discoideum hybrid signal transduction histidine kinase D and similar domains. Dictyostelium discoideum hybrid signal transduction histidine kinase D (DhkD) is a large protein that contains two histidine kinase (HK) and two REC domains on the intracellular side of a single pass transmembrane domain, and extracellular PAS and PAC domains that likely are involved in ligand binding. This model represents the second REC domain and similar domains. DhkD activates the cAMP phosphodiesterase RegA to ensure proper prestalk and prespore patterning, tip formation, and the vertical elongation of the mound into a finger, in Dictyostelium discoideum. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.7788e-26
NZ_CP022098.1\|WP_157758144.1\|109675_111307_-\|hypothetical-protein	gnl\|CDD\|238613	cd01286, deoxycytidylate_deaminase, Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the enzyme is allosterically regulated by the ratio of dCTP to dTTP not only in eukaryotic cells but also in T-even phage-infected Escherichia coli, with dCTP acting as an activator and dTTP as an inhibitor.	3.83652e-25
NZ_CP022098.1\|WP_095983399.1\|102055_103393_-\|type-II-toxin-antitoxin-system-HipA-family-toxin-YjjJ	gnl\|CDD\|236623	PRK09775, PRK09775, type II toxin-antitoxin system HipA family toxin YjjJ.	2.95504e-158
NZ_CP022098.1\|WP_095983405.1\|111426_112404_-\|VWA-domain-containing-protein	gnl\|CDD\|238119	cd00198, vWFA, Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains.	8.34435e-05

>NZ_CP022098.1|WP_095983402.1|105357_106224_-|MBL-fold-metallo-hydrolase
MDGRQRPKGVPAALVCHCLLVETEQGLLLVDTGFGLQDVLHPRPRLSSFFLGLNRPQLHEGLTAVRQIERLGFKASDVRHIVLTHLDFDHAGGLDDFPMARVHVMNAEVEAAAAQRTWLDRERFRPRQWRTQPHWVTYAMPRGGERWFGFECVRELSGLPPEILLVPLVGHTLGHAGVAIQQPDGWLLHAGDAYFHHQEMNPDRPTCTPGLLLYQELMQKDGRMRRLNQERLRALVRHHDRDVKVFCAHDAVEFERLEEDARFHEEHALRGLGSVRPETGLTEPSLPT
>NZ_CP022098.1|WP_157758143.1|104385_105207_-|methyltransferase-domain-containing-protein
MNATSTIFSDFHDLDQATTSKEAVRFLDALNTSQQVQEMQQLTHLMLGVAPGQRILDAGCGVGDVTRDLATLVGPRGHVVGVDLSEALLAEARARTQGTGLSVEYRKGDLHTLDFPSESFDRCRSSRVFIYLDDPRKALSELLRLTRPGGAVVLFEPEFDTWALDGPDRGVVRALIHFWTDQLRNPWIGRQLPRMFHSLGVDQVAMRPVVGTWVPRMLETFGMYPVLEKAIAERVVTREQVDAWLQFLKEGEKNDSFYGCMAGMVVRGIKPGP
>NZ_CP022098.1|WP_157758142.1|103510_104356_-|alpha/beta-hydrolase
MSIAHEEGFFESTPGVRLHGQAWRPSGEPRSVVGIVHGVGEHGGRFTNVVEALVSRGHAVHAFDLRGYGRSSGQRGHVRSWSEYQDDMRAFLKRISTSEPGKPVFLYGHSMGGLVVLDYVLRYPEGLAGIIISGAALESVGVAKPWLVNSARVFSRLLPRLPLPVPLEAEALSSDPAWVKRYREDPLVHRKGTARWAVEALDANEWIKAHAAELRVPLLMLHGAEDRINTVEGSRRFFDAVKLTDKKLHLVPGGYHEPHNDPGKEKVFELVEEFLSAHLPH
>NZ_CP022098.1|WP_095983399.1|102055_103393_-|type-II-toxin-antitoxin-system-HipA-family-toxin-YjjJ
MSSLERMLGVLSRLQVAQAKDLASELGVSQPTVSRLIQEAGERVCRMGQTRATRYARTRTLPRLGTRQPLHRISETGKVERFGEVHLLEGGRHWFTLEQGRSWLHLPAGTGSLFEGLPPFIVDMCPQGYVGRTFSRQHPELGLPLRLGDWNDDHHLIALAVHGADCVGDLILGEDSLNQWLAHPREPTDRSAYPELARRSDREQPGSSAGGEHPKFLTYSEGRHVLVKFASDDEGAIARRWRDLLVCESLSLEVIREAGIEAATAHWFDEGDYRFLEVERFDRVGERGRRGMISLKALDNEYIGDMGPGSSWTSVAPKLQAAGFIQAEDARRMRWLDVFGQLTGNDDRHFGNLSFLETGEGRLRLAPAYDMLPMRFVPSTTAVVDRPFVPDPPTARTLDIWPEAAHHASLFWTRVIEHEALSDGFRALARQGKEALEALRERLPL
>NZ_CP022098.1|WP_095983398.1|101520_102009_+|serine/threonine-protein-kinase
MSANRAPLLPIIGLILMSLGCPSAGVPLRADGTPGPEKCPEEALKTMRILRMHVSDAADVELDANQIGARPITLYEGPVESVLDGSLGTLDPATRLYGRVWTSGPQVVVRYYEAKPPDGDTVPICAVARLGDGQLRKRPESKPGTAIIEFSNASVFVVDSFR
>NZ_CP022098.1|WP_157758141.1|100624_101509_+|DUF2381-family-protein
MARGRDVNVRSAYIFGRHDEGVDRLYVTPDAATILRFQQPCDAAGTKMLGWEGRFEPVGCTGKSVVVVPLVRIEPEDRFLLVVRLADGTEVPFTLSGATRKEGEWPDQQVNVFLAPDTREELKDQLKTAREMRDGLMDDVRRFYREDTPDHALAKLLAAGASKQTPFKLLKKRVIKSEGEETTVRIYKGKAKAAVLFTVTNHDPSKPWNLLEARLVTIRPGENPEPYVFGDKKPFALRADRDEIAPGESGNVAVVVDRSAFTTENGNAELILEIYRKDGWRQAYVVLDERLTRQ
>NZ_CP022098.1|WP_095983396.1|99477_100263_-|DUSAM-domain-containing-protein
MTEETDWEELRTLAQDVFESGAPLELTDETRALLSRTAQQVAISQQDAEDALRGLSTATTLLREIRQRIRDGSHRLGDALDRAGTRQRKGDLDGAQQAMRDLLAVEVVPLYRKHAEVQLEELTGLMEVRATGRLNPDLPDRPQLAVLAQRIQQGHALELTDDLRVLLRRTTPTAAISEAETEEALKSPEGAETLIGMILSRFQKGERRFLRSMYRMTSLRDAGDLEGTRQQMRDVLAVEVVPIYREMAEEQLRGLDSPPPE
>NZ_CP022098.1|WP_095983394.1|98152_98941_-|DUSAM-domain-containing-protein
MSAKINWDSIRALARRVLEHGNPLELTEDTRVLLLRTALEVGISQQETEDALRGVDTATTLLKEAMRRINDGSDRITRALRRMSDLRDKGDLDGACQQMRDVLAVEVVPLYRKQADKRLKELTQLSEVAATGRVSADLPDRPQLAVLVHRVQQGHALELTDDLRALLHRTAPTAGISEAETEETLKSPGGAESLMGMILSRFRDGRERITRALFRMTSLRDAGDLEGARQQMRDVLAVEVVPQYRQMAEENLAGLDRPPLES
>NZ_CP022098.1|WP_095983393.1|97280_98084_+|hypothetical-protein
MDRFTLGGDHEVSVMVKLALLGESFPSQLRENPQALRDVQVVWSGTSIEAFRNEVPAKRPDVLALDFLELNAVQSDVVPALLENSRARHAIVTYRFARRGVLQQYPEGKVRLLQGPISLSLLRAHVHLAVLDDVLKPQTVPALEIVRTPPPPPTPPPAPVSPIQMNAPGSATMATVTVLARPKPPRYTQEQLGTLLEYASSVKCECPNHLSQIVSSLQAFEEYSKQCENRNDADREVHGLLYRYTASARAVMEEALDALVKHENIPL
>NZ_CP022098.1|WP_095991721.1|94807_96610_-|tryptophan-synthase-alpha-chain
MHCGACTSPDTCGGGGVAHVCGRAPCTPTTCAALGKNCGTLSDGCGGTLECGTCAADETCGGGGAPNVCGQAPCTPTTCAALGKNCGTLSDGCGGTLECGTCTGNATCGGGGVPNTCGQPPCVPHTCSEMKQECGLLPDGCSDAVLDCGTCSAGETCGGGGTPNTCGPASCSPATCAAQGKNCGLVSNGCGGLLDCGMCYGGQTCGGGGVPNVCGSAHCLPSTCEELGKDCGLVPDGCGGMLDCGTCSAGETCGGGGTPNVCAVAGCRPSSCGLLGKTCGTVADGCGGTLECGTCSAGETCGGGAGGANVCEQTASVCVDQDLGSALPVRLKGSTRHARDDHQASCGGLGAPDRGFLWTAPRTGTYGFDTARSAMHTLVSVRQGGCGGAELACATGGISYGGGARVSVRLTAGQRVLVGVDSPQGGDFSEGDFELHITQQTAAEAASCFDGADNDGDRWVDCADTDCQGDVLCDGRGCSDINLGSALPVTFLGDTVHAGDGFQGTCGELLQQDRAHLWTAPRDGTFVFDTSGSDGNALYVLTGCRGQELACASSRTGAPRVKLTLEKGRTVLVVVDGMARSDTAWPIRYTLHISEDAAGP
>NZ_CP022098.1|WP_157758144.1|109675_111307_-|hypothetical-protein
MASEGTPHNLSKDKKDEFNRRAAQSAPELVIGLVGAIGTDLEAVSKVLSTALMAEAAYQARTIRLSSLLHEIEGLGVDLNSKGDKLTYYEKHMEAGTRLRQKMERPDAMAWLALSAIRQARTEMLMADRRNGRRAYILHSLKRREEVESLREIYGSAFFLMSAYAPRDKRVDKLSRSISESRGQWRPMDLRSEAEALVRTDERDLDEPMGQDVQRAFPEADVFIDATNPREMDLSIRRFVRLIFGHRFHTPTRSEWGIFFAKAAAMRSAALGRQVGSAITTPTGELLAVGTNEVPKAGGGLYWEGDEPDGRDFVGGVDTSDRHKHDLISELLRLLQEKQWLSEAYRSMDVQELRTQVLKKDAVGTGPWRDSRVTNLIEFMRPVHAEMASLMEAARRGVSVQGSVMYVTTFPCHECARHIIAAGISRVVYVDPYPKSLAADLYSDSVSLEGSEGGSTGKLIFSPFVGVAPRRYMEFFELKGERKDKDGSVIAWVPTEVVPKHSGNYTVYQSMEVEHLGRFASIVERIGLNFRTAAESGEEDSSE
>NZ_CP022098.1|WP_095983405.1|111426_112404_-|VWA-domain-containing-protein
MAGHEVIMKPFSDVHRLGNKVVATLLHDPTVEGLDVALYMDGSASMEDEYGPRGILARLAPVKNLVEPQMRWMLEYLANKDRDGKVRVAYWATGDGSQLEEVGELTGPQAKDFRFPGPRAYGKATVMLPVLRDFVAHMKQQVQVGARRGLAVIVTDSQISDAPNVMAYATQVAKEIASGRLPRMNFVFVGVGEQVDEEQMEEISHETYPGVGHLWCHRIADRMEEMAELVAVLVDETMTVAAGGTVYDEQGNTLKAYEGRLPAVLEFDVPATCKAFTLEVAGQRFTQPIPEEHEEDEDHHEEERAPEPEPVSSPAPRKKHRGHGH
>NZ_CP022098.1|WP_095983406.1|112403_113348_-|VWA-domain-containing-protein
MGHEKPVEPFSDLHVEDGKVRAVLLHDPTVEGLDMAIYMDASGSMKEEYTYTRPKRSFLEWLQDAPLKEESNQVEPQVRWMLEYLATKDRNGLLRVAYWACGASGRDVDVLGEYKGTDVKQHKFPGPQRLGNHTYLEPALRDYVSYLKEQVSQGARRGCAVIVTDGRLNDADEVKKFSAKVAKDIASGKLPRLNFVLVGVGDNIDEEQLEDIAHQEFPGVGHLWCHRIAQEITQVAELVAVLVDENMTVAAGGTLYDDKGRVVKTYEGRLPAVLEFDVPEGTQSFTLEVNGQRFTQPLPDEDDHHDEDEDEDHH
>NZ_CP022098.1|WP_095983407.1|113406_114711_-|hypothetical-protein
MRPPRYFVPHATSPAEPLALDLSAVVHAVDAFRLAGPSGEREWLVCTDITGDLVCVPAEEREHLPASTRAQFTHHELVSGRTPRRILAPALFLLSVELVEHPADAQGVNDPVYLYGRLSGPHPGATPERVPGQLTVTRGDLLAGLVHGAADALHYAHDPESRLPPRAWHALLPGDRPEHLAQGEGLVLAYPAVPLDMQTRHAGNGPLVATLLHEVLEALQHAARAHGGPRALAELELPVPSRMLAIAELESRGYEVKGDVAILRRKHPGLVNRLAEWLNPEKLTVPREAGTPEFLDLARQALDVLPGWPSETERALRSRERAGPITVPSPTPLAPSAPRPPPAPLPPRAPPAPARPSDWMQDFLDAHARPGGTQPRITRSRAAVTPPRPATSAEWMKDFAPEPAKPSKPAPKARPATSAPEQTSKPEWMSDFED
>NZ_CP022098.1|WP_095983408.1|114761_116114_-|RtcB-family-protein
MSWTQQLEKVAPGHFVLPKTKTMRVEAHLFLSDKLLWGEGPESPGLEEAVFNQVVNAASFPGVTRVAVTPDCHVGYGVPIGTVVETEGVLLPTAAGYDIGCGMVQLQTTLTAEDVADPAKRRQWIDEVTRRIAVGVGASRVQKQRRIDARTFAEVVRHGAQALGRHASATERDFLPVEDDRVDIPTRAYEKREQLGSLGGGNHFTEMQVDESGRVWVMLHTGSRGFGWNIAKHFFVEGAAALGLGKHSEDFIWLDASSRLGKEYWNLHNMAANFAVANRLLIGEAVCGALEDVFGGTASIYYEISHNLIQKESGRFVARKGATRAFPGGHPALTGTPWAKSGHPILIPGSMETGSAILFAEKGAEQSIYSVNHGAGRRLSRGEARRVLDQDETDLRMMEADILLNTRTTPLDESGPCYKNLDDVLNTVEMAGLATVARRLKPVACIKGAD
>NZ_CP022098.1|WP_095983409.1|116319_116613_+|hypothetical-protein
MGLFGALVVAMAVQAGPVEVKAAPVFNPSLCAKKRVDSCGCHHVYGVRHCHSKRQSEHCEGMVRVDDASQRGASQVDDFLSTLPDTAAHEHEDTATL
>NZ_CP022098.1|WP_095983410.1|116727_117099_+|response-regulator
MSASTSSILLVEDDPDIRDTVSELLELEGYQMVTSPNGQEALEQLQHMKRPCLILLDVMMPVMDGYAFMRGMRADGQLADIPVVVTSASHKPPEGACAYVPKPIDVDRLLAVVKTYCRSGTCE
>NZ_CP022098.1|WP_095983411.1|117121_117307_-|hypothetical-protein
MSLDVSVRSVALRIEDTELKKALGHPEPTKSGLVVFDPSAPEADETDPASEEPNVEPVAHP
>NZ_CP022098.1|WP_095983412.1|117547_118345_+|pilus-assembly-protein
MASSPFPRRRHESGQAAVEAALCLPLVVFLILGTLQLFMLLQARILAEVAVYRAVRAGSLNHANCKAMTHAAVVTMLPTVSATTSGAQLAEAFRDRRNNRLYARGSSGKLFTEGPVVEIVRESPDVGWVRGLSGGEDLLFDAPTDSAAELRRRTLEIRMVAWYYMRIPFADWVLNRMFLAHFKLKRYTAANPLMPAQRNAGGWDDGGVTLPSGGWPGGDLGDRMVEWSAQGHYLFPIQVHAAMRMMTPVKATHFQGGAACRLHSF
>NZ_CP022098.1|WP_095983413.1|118323_119859_+|pilus-assembly-protein
MPSALLLRRERGQAMVLFALTLLLLTLMVLMTLGFGMRAKERVEIQMAADAAAYSQAVSVARTFNAIAVMNRAQVAHMVAMAGTQSLISYGSQQYAAMMHGPCPIPTAEWSSLDEAAATQVQQLQGRAGAMYRASLALYGKLLGNHLAGQQLAARMAREVNPELRALPEGDRKSLAEVNGGNGSLDYDDLMDQERDGTVPKTSGAVLPTGGNQGRVTLNATMGSLGWTWVHNRESGSAGFGTGGAAQNPSFKHYGSASQMDSSTYSTVSGRNSWAHDHGRAVPIICPDGSTVPDIEATDTWVMSDEKQSKQDQHVYGAKPPPGQGSEGDTTVDERHTLGACVVCPGIWPYSVGFNVGLLQGNAARNDFGQPKLYTVLSRDYASPSRRKRPDPWNLFFRFRFANDTVEFDNASSEGRIRSTGRGDVQRNQVALSAGLAYYHRPRPAAEGGGWREPPNFLNPFWRATLVSPEGADDDKPANSLEQAGFTEHAGALRRLDGVGFRGGSPEGARY

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_4

583613-583722

Orphan

Consensus_repeat	Method
GCTGGAAGGCCTTCCTCCAATGGTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022098_4

>merge|NZ_CP022098|4|583613-583722|CRISPRCasFinder
GCTGGAAGGCCTTCCTCCAATGGTGGAATGACGCCATCTCTCGGGAGAGCAGTAAACCCAAGGTGGACCCGGTCCCCAGAAGACGCTGGAAGACCTTCCTCCAATGGTGG

>NZ_CP022098|4|4|583613-583722|CRISPRCasFinder
GCTGGAAGGCCTTCCTCCAATGGTGG	AATGACGCCATCTCTCGGGAGAGCAGTAAACCCAAGGTGGACCCGGTCCCCAGAAGAC
GCTGGAAGACCTTCCTCCAATGGTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_157758194.1\|579285_579555_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095983753.1\|579638_580295_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095983766.1\|594201_595026_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235545
NZ_CP022098.1\|WP_095983761.1\|587295_587931_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|176885
NZ_CP022098.1\|WP_095983759.1\|585131_585650_+\|YfbM-family-protein	unknown	unknown	gnl\|CDD\|378105
NZ_CP022098.1\|WP_157758196.1\|595492_596347_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095983755.1\|580742_581276_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095991754.1\|587962_588298_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095983750.1\|577151_577514_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095983754.1\|580357_580624_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095983763.1\|590890_591088_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095991752.1\|578237_579275_+\|trypsin-like-serine-protease	unknown	unknown	gnl\|CDD\|238113
NZ_CP022098.1\|WP_095983756.1\|581415_581871_+\|DUF2267-domain-containing-protein	unknown	unknown	gnl\|CDD\|378360
NZ_CP022098.1\|WP_095983757.1\|581894_582230_-\|thioredoxin	unknown	unknown	gnl\|CDD\|200072
NZ_CP022098.1\|WP_095983760.1\|585669_587184_-\|HAD-IG-family-5'-nucleotidase	unknown	unknown	gnl\|CDD\|377556
NZ_CP022098.1\|WP_095983765.1\|592105_593974_+\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP022098.1\|WP_095991753.1\|582371_583289_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NZ_CP022098.1\|WP_095983762.1\|589935_590865_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095983751.1\|577530_578082_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237284
NZ_CP022098.1\|WP_157758195.1\|591353_592109_+\|DUF2381-family-protein	unknown	unknown	gnl\|CDD\|370554

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095983761.1\|587295_587931_+\|hypothetical-protein	gnl\|CDD\|176885	cd08876, START_1, Uncharacterized subgroup of the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domain family. Functionally uncharacterized subgroup of the START domain family. The START domain family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. For some mammalian members of the START family (STARDs), it is known which lipids bind in this pocket; these include cholesterol (STARD1, -3, -4, and -5), 25-hydroxycholesterol (STARD5), phosphatidylcholine (STARD2, -7, and -10), phosphatidylethanolamine (STARD10) and ceramides (STARD11). Mammalian STARDs participate in the control of various cellular processes, including lipid trafficking between intracellular compartments, lipid metabolism, and modulation of signaling events. Mutation or altered expression of STARDs is linked to diseases such as cancer, genetic disorders, and autoimmune disease.	1.16075e-36
NZ_CP022098.1\|WP_095991752.1\|578237_579275_+\|trypsin-like-serine-protease	gnl\|CDD\|238113	cd00190, Tryp_SPc, Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad residues.	7.58888e-30
NZ_CP022098.1\|WP_095983766.1\|594201_595026_+\|SDR-family-oxidoreductase	gnl\|CDD\|235545	PRK05650, PRK05650, SDR family oxidoreductase.	7.95041e-132
NZ_CP022098.1\|WP_095983756.1\|581415_581871_+\|DUF2267-domain-containing-protein	gnl\|CDD\|378360	pfam10025, DUF2267, Uncharacterized conserved protein (DUF2267). This domain, found in various hypothetical bacterial proteins, has no known function.	0.000132861
NZ_CP022098.1\|WP_095983757.1\|581894_582230_-\|thioredoxin	gnl\|CDD\|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	4.52814e-38
NZ_CP022098.1\|WP_095983759.1\|585131_585650_+\|YfbM-family-protein	gnl\|CDD\|378105	pfam08974, DUF1877, Domain of unknown function (DUF1877). This domain is found in a set of hypothetical bacterial proteins.	2.10748e-47
NZ_CP022098.1\|WP_095983765.1\|592105_593974_+\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.28557e-42
NZ_CP022098.1\|WP_095983760.1\|585669_587184_-\|HAD-IG-family-5'-nucleotidase	gnl\|CDD\|377556	pfam05761, 5_nucleotid, 5' nucleotidase family. This family of eukaryotic proteins includes 5' nucleotidase enzymes, such as purine 5'-nucleotidase EC:3.1.3.5.	0
NZ_CP022098.1\|WP_095991753.1\|582371_583289_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.02161e-74
NZ_CP022098.1\|WP_095983751.1\|577530_578082_+\|hypothetical-protein	gnl\|CDD\|237284	PRK13108, PRK13108, prolipoprotein diacylglyceryl transferase; Reviewed.	0.00879926
NZ_CP022098.1\|WP_157758195.1\|591353_592109_+\|DUF2381-family-protein	gnl\|CDD\|370554	pfam09544, DUF2381, Protein of unknown function (DUF2381). This family consists of at least 8 paralogs in Myxococcus xanthus, a member of the Deltaproteobacteria. The function is unknown.	2.30153e-13

>NZ_CP022098.1|WP_095991753.1|582371_583289_-|LysR-family-transcriptional-regulator
MPPTPPLLDDMLVFAEVADTGSLTAAAARLGLRKSTVSRRLAALEERLGTRLLERNTRRLRLTEAGREYHAHCARLVAEARAVNQAMSESRDIPRGTLRVATFSLLGELLTPVIADFLLRHPQVRVEVSLAPAHVDLVAEAYDVALRTGPLVDSALVARRLGHVRTGYYASPAYLGRRGTPRTPEELAHHECVLVAEPGTDEVWFFTGPGGARTMPVSGRLQVPSVRAGHAAARAGLGLVRLPTVLVAEDVRAGALVPVLEAVSPPGLALYAVHPSRQRMPAKVKVFLEALTRGGPGLPWEDGPR
>NZ_CP022098.1|WP_095983757.1|581894_582230_-|thioredoxin
MAGDIIDVRDAEFGGQVLRADGPVLVDFTAHWCAPCRALTPALEALATANKERMKVTRLDIDENPETAQAYGIRSVPTLLLFKQGRVVGQLVGAQPRQKLESAVEKFLQAP
>NZ_CP022098.1|WP_095983756.1|581415_581871_+|DUF2267-domain-containing-protein
MSDTPPGNPLSRGDKRPPSRPGPSSAAFTTSLVQEGRLDPGLAECAAASVVTALLRNLELDEDQEPRGHLMRRLVEFLPARDAGKGSLEPISGQEALFTSVARELRLEVSAVEPLVRTVFQTLRGFLSEGECQDVERGLSWDLHYLWRRTQ
>NZ_CP022098.1|WP_095983755.1|580742_581276_-|hypothetical-protein
MSDSVSMKDAVSYSTNGALSILGQGNLLGENYLMPVLNGGGRKKRARKQEATPKPGFAAALKLVVQLGREKEKEVGKTALSRCPRCGHVGPTEQDFGIRVIRGERRPQSWCRSCRKVNLPPLKALPHAANRKVKATLVETANEKPERPRNAPKPVPSQEDGWLFPPDALGKRKRRKS
>NZ_CP022098.1|WP_095983754.1|580357_580624_-|hypothetical-protein
MAVRTDIVGIKNRRQVGVHAAQPSPQASKGRAIPFHDEIPLLRRERLLERVTLGPAAEPHHPKTPRLATSVNGRKKPPSEMHIRRSGG
>NZ_CP022098.1|WP_095983753.1|579638_580295_-|hypothetical-protein
MSDSLFSSDVETADTLHLGRQWLGDLLDLALSLLLGWGLLRTLDVTRTPGRLIAVTAGVWCVVCLVGGLSGWTLGQALVGLRLVRGDHAPGVSRGAARAPLALVELLVSPILQRRVFDRTLALETKSMPPWRGGLPWKGAWLVLALAAVWFMVTPTRTESLRYLKTLDGWRCCHGRATPAPSRCEDAVSRAVREAAGGDAQARAVVADCPTAAAAMSR
>NZ_CP022098.1|WP_157758194.1|579285_579555_-|hypothetical-protein
MAVRTRMAGTKNPRRVTSVDEAQSNRQATNGKKTVPRDQAAALRRQKLMRKATPGPAMTEPVGHGPATTEVRPTQRTVTRRKMKRGNAL
>NZ_CP022098.1|WP_095991752.1|578237_579275_+|trypsin-like-serine-protease
MALVARRVRCAGESLTLLCSGALIAPDVVLTAAHCLDVFGPEGAYEVFFGARLLPETHTQGRFVRVARAVRHPDYERETHAHDVALLRLAVAVEVPPLRLPGPGEDVPSPGGAARVVGFGDTRDGDAPPGVRRQGGLRVTEVRPDVFLAGPDPAMSCVGDSGGPVLVRDAEGGEVLAGVTVSGDFACQKEAVNLRVDAVRDSFLQPLLDEHPEPPGPRLALDALCSGTCTRDADCPAGLACAETADASRRCFLPALQPGDYGGPCVEDAQCGAGGVCARLEPEGDDSCRCFTPCAEPVSEPSSEPPSEPSKGEDIPRGCTGAPGPGALALGALAAWLYRRRAPLP
>NZ_CP022098.1|WP_095983751.1|577530_578082_+|hypothetical-protein
MNPRFRVVVPLVACLVLGGTLLWALRDVSSAPSPEAVAAAPSSSASSPSVPGPPMSGSSGSPPEGVGSAVGPAPIASQELAAGEASLPESEDANLPPQENDPIEPEQPQTAAWRHEKLVRITELLDRDVERLEAERQAASARGDEGESRRLAVQLTRHRARLGSLREETAVMADAARQEEQTR
>NZ_CP022098.1|WP_095983750.1|577151_577514_+|hypothetical-protein
MRRPGLALLVGALVGCAPSTASKTEAARETVRRFFTELPSGDCAVLGPMLAGEGGSSCEEKVADLSAHGFSLVEVLDAKVDGRDADAVMVRARVARDGRVREQPMLLRVERHPEGWKLRL
>NZ_CP022098.1|WP_095983759.1|585131_585650_+|YfbM-family-protein
MSIQGNLRRVGADQLRALLASPEQVNDIVHPPEDEDLDEDGSSNADHLPLEKNWHGLHFLLTATAWEGSPPLNFIAAGGQRVGDEDVGYGPPRAFTPQQVKEISRALEGLDGEGLRRRFNARKMDELEIYPQGWSDNDDEESLASLLEDFDTLRSFLREGAEQGQALLVYLN
>NZ_CP022098.1|WP_095983760.1|585669_587184_-|HAD-IG-family-5'-nucleotidase
MIGHLKAPPPERGLFCNRTLNLRAIKAIGYDMDYTLIHYKVEVWEKRAYEYMRDRLAAQGWPVAHLTFDPVLAMRGLIIDTEKGNLLKANRFGFVKKALHGTRPMSFESQRDEYMRTVIDLSERRWVFLNTLFSLSEACLYAQVVDLLDDGKLEGPMGYNDLYEHVRRSLDATHMEGALKAEIIADPARYVQADPDTPLALLDQKHSGKKLLLITNSEWAYTLPMMHAAFDPYLPKGMTWRELFDVVIVSARKPEFFTTRSSLFEVVTIAGQEGLLRPHSGSLKPGVPYFGGSASEVERSLGMSGDEILYVGDHMFGDVHVSKSALRWRTALILRELEDEIRAISSFRATEARLAERMQQKERLEAEACQVRLELQRRRLGYTARDESLPGDEQLHARSLELRAQQEALDAELGPMARAASELSNPVWGLLTRAGNDKSHLARQVERYADIYTSRVSNFLFATPFVYLRSPRGSLPHDPTTPGGTPVFPHPTTGGDTGGDSGGA
>NZ_CP022098.1|WP_095983761.1|587295_587931_+|hypothetical-protein
MRNSLGVSLLVWAVATVAVGEEKWETVSTGPVSIRVRLRPDIPGGREVWAEGSMAVGLPHVRAALRNHANFRLWMPYVTESRVLDEAPGTRLTYTQLDFPLISNRDYVLRVVEEEGHTEDGTVTFLQRWTPDNEALPDRDGVVRLRHNSGSWLFTPEGEDRVRYVYRFTVEPGGSIPGFLAGVGQKDAVLDTVRAVEKRARQLASQGTPPP
>NZ_CP022098.1|WP_095991754.1|587962_588298_-|hypothetical-protein
MAMLFAVRDGIKDAHAGRPAYFWALFTDPAHRRERLREGWHAVGRIFLLAVVMDVIYQLTVLKGPRPLQGLLVAVVLALVPYVLLRGPVNRLARGLLHHRPRARGPGSPAR
>NZ_CP022098.1|WP_095983762.1|589935_590865_+|hypothetical-protein
MSHERRLSPVELLRQLTLSVERLAAQGLASGAVRGATEELRAGHPELDGQLQAVFQDVLTLLERMVHEAAGRPVRPPEEWSRRVAEGAVRGAVEELRRSMPGVDAFSHEVLERLNRLLERSTRVAANRERELRMPGTRARIAAAGAVRGALGELHDAMPRLAPMAAGLSSQVGRGFVEGLGAKAREERDVFAAILERAGRGFIHALVEQLDTELRARWGVGEGKVGRVVEDRAEQVAAACVRGATGELLRQVRSLGGSSSAGEALQRAGREVSSGILSALAEGLRKPFFAAAGASCALLLTALLVTRAR
>NZ_CP022098.1|WP_095983763.1|590890_591088_-|hypothetical-protein
MRVNVQGSRLRVLGGVLLLLLLEGCATGAPPPGLLGNRRPRPAPRESPPAKPERPPRQAVTTYTL
>NZ_CP022098.1|WP_157758195.1|591353_592109_+|DUF2381-family-protein
MLQRRTLVHPSSPERVPPLELHVAAGVATLVSFAGCSRPEVLEFGQGHPSLRLIDMSGGALILSPSADLAPGERVPLVVRLAPDAEPLRFVLVTRRDAVDVRVQVVRATSGSEEEGVDGVARSLLDAPGAQATLELPQRVAEIDARNSQGRVDSVLWMGRRFFATVSVRGGNKGAALWPLVQVRMRAMLPDGEVWEGPVRLVSGVAGSTRQRHIATGLLPGGASGVELALDEANTAGVFQPLSRKDPSTHP
>NZ_CP022098.1|WP_095983765.1|592105_593974_+|serine/threonine-protein-kinase
MSPPRHPHELRAGDFVRDFRIVRRLGVGGFAFVFLVERGGLQFSMKMAARPLSAEDPDQVDAWMRREVASMDQLVGHPLVLPVFEWSRWPDARTGYAYFLTAYVPGDTFHVWRWRRRASLHESVGVLSTLARTLEVLHWRGMCHRDLKADNVLVREADGEPLLIDFGSAHLPGARILTEGVAPGTLYCQPPEVISFLFSDARLPGTRMRALPSADLYAFGVLLYETLTQCRPFNSRLPLSRLLIAIASTPVPDPRRFDPSIPEPLAALTMSLLEKEPAKRPPNAEAVRLVLERLREEGADSGVWRAPSKRPSECAWGRELPEEMELLNEAGEGLPAALEAWRPREGRRLTGVRPGRLAALALVLGVLGIGWMCLRVAHPPGWEEGVRTEPTAPVPPVPFEKGTQPVPSSLGPESSPDSTPVPLRSRRCALLTGLLGVSAAQLAGCATVPRQPDPQGYLSRCPPEARATPVKLGIKPDEQPSFLTPTSGTPASDERIEDGGPLNIKPGPVSADMLVEIGGNELYVTIFGVAEMSPNRVHMRFDRLRMPEGVEYPICGVAVDDMHQYGLATWQKFAVPGAGVDPSRVDTTGGGVVLNYPRFETVLQGPEGYEVPRIRLAPPDWR
>NZ_CP022098.1|WP_095983766.1|594201_595026_+|SDR-family-oxidoreductase
MTNQRIFITGGASGLGRSIALRYARAGWRVCIGDVNPTRGAEVLRELQALAPAALYMPCDVTRAEDLRAVAERLTADWGGVDVVVNNAGVAAPGAIEDVPLEDWQRVLDINVMGVVRGCYVFTPLFKRQGQGHFVNVASMAGLLDVPRAACYNASKAAVVSLSETLQNEFVGTRLGVTLVCPSFFKTNLAESLRNVDAATRAAVNRVLERSTVSAEDIAEQIFQAVRQRTFYVLPHVQGRQAWLMKRLLPRPLYMRLISAQLRRMRGSDSRKTA
>NZ_CP022098.1|WP_157758196.1|595492_596347_+|hypothetical-protein
MRNSSTLNGSIFFAALLSFTMGAGEAQAAGTFMGAWDLTGDGVAETVYNNLSSIEVRQSNGSTRSYSITNAAWTLLTVADLDGTAGLELAINVGSSIKIITHRTGSVRDYFISSGPWAPLGYHDLNADGATDIAVNTGPAVRTIKLKTDTVRDYAISNVSWAPIGFADTDGDGGIDIVVNNVRAVKIINDRTASSRDYAISSVSWAPIGIIDTDGKPGAEVVINNLSSVKIIRNRDASTRDYAVGSPSWSVQMIADLDGKAGNEIMLNLGTTTKTIYDASGQYY

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_5

663558-663679

Orphan

Consensus_repeat	Method
TCCGTCTCGCCCGGGTCCACCAGGCCGTTGTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022098_5

>merge|NZ_CP022098|5|663558-663679|CRISPRCasFinder
TCCGTCTCGCCCGGGTCCACCAGGCCGTTGTGGTTGGCGTCTTCCTCGCCATCCGTCAGGCCGTCCGCATCCGAGTCCTGTTTGGCGGGATCCGTCTCGCCCGGGTCCACCCGGCCGTTGTG

>NZ_CP022098|5|5|663558-663679|CRISPRCasFinder
TCCGTCTCGCCCGGGTCCACCAGGCCGTTGTG	GTTGGCGTCTTCCTCGCCATCCGTCAGGCCGTCCGCATCCGAGTCCTGTTTGGCGGGA
TCCGTCTCGCCCGGGTCCACCCGGCCGTTGTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_095991762.1\|655021_655393_-\|response-regulator	unknown	unknown	gnl\|CDD\|381147
NZ_CP022098.1\|WP_095983817.1\|654340_655000_-\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|379056
NZ_CP022098.1\|WP_095983829.1\|674825_676073_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377450
NZ_CP022098.1\|WP_095983823.1\|664208_665594_-\|ferritin-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|153097
NZ_CP022098.1\|WP_095983814.1\|650326_650953_+\|TonB-family-protein	unknown	unknown	gnl\|CDD\|367555
NZ_CP022098.1\|WP_157758203.1\|676462_676786_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095983821.1\|659308_660943_-\|PAS-domain-containing-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226702
NZ_CP022098.1\|WP_095983826.1\|668330_668915_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095983819.1\|657122_658817_+\|GAF-domain-containing-hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl\|CDD\|274362
NZ_CP022098.1\|WP_157758202.1\|652189_652564_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095983825.1\|667550_668312_+\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|187608
NZ_CP022098.1\|WP_095983818.1\|655422_656565_-\|response-regulator	unknown	unknown	gnl\|CDD\|274060
NZ_CP022098.1\|WP_095991761.1\|650959_652012_-\|chemotaxis-response-regulator-protein-glutamate-methylesterase	unknown	unknown	gnl\|CDD\|234828
NZ_CP022098.1\|WP_095983828.1\|670415_674576_+\|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|379311
NZ_CP022098.1\|WP_095983824.1\|665903_666662_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095983827.1\|669103_669562_+\|group-II-truncated-hemoglobin	unknown	unknown	gnl\|CDD\|381282
NZ_CP022098.1\|WP_095983820.1\|658857_659316_-\|response-regulator	unknown	unknown	gnl\|CDD\|381108
NZ_CP022098.1\|WP_095983816.1\|652707_654357_-\|chemotaxis-protein-CheA	unknown	unknown	gnl\|CDD\|223716
NZ_CP022098.1\|WP_095983830.1\|676086_676410_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379603
NZ_CP022098.1\|WP_095991763.1\|666736_667444_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095991762.1\|655021_655393_-\|response-regulator	gnl\|CDD\|381147	cd19920, REC_PA4781-like, phosphoacceptor receiver (REC) domain of cyclic di-GMP phosphodiesterase PA4781 and similar domains. Pseudomonas aeruginosa cyclic di-GMP phosphodiesterase PA4781 contains an N-terminal REC domain and a C-terminal catalytic HD-GYP domain, characteristics of RpfG family response regulators. PA4781 is involved in cyclic di-3',5'-GMP (c-di-GMP) hydrolysis/degradation in a two-step reaction via the linear intermediate pGpG to produce GMP. Its unphosphorylated REC domain prevents accessibility of c-di-GMP to the active site. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	2.15791e-32
NZ_CP022098.1\|WP_095983817.1\|654340_655000_-\|GAF-domain-containing-protein	gnl\|CDD\|379056	pfam13185, GAF_2, GAF domain.	1.21719e-08
NZ_CP022098.1\|WP_095983821.1\|659308_660943_-\|PAS-domain-containing-sensor-histidine-kinase	gnl\|CDD\|226702	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms].	2.46037e-52
NZ_CP022098.1\|WP_095983829.1\|674825_676073_-\|hypothetical-protein	gnl\|CDD\|377450	pfam05076, SUFU, Suppressor of fused protein (SUFU). SUFU, encoding the human orthologue of Drosophila suppressor of fused, appears to have a conserved role in the repression of Hedgehog signaling. SUFU exerts its repressor role by physically interacting with GLI proteins in both the cytoplasm and the nucleus. SUFU has been found to be a tumor-suppressor gene that predisposes individuals to medulloblastoma by modulating the SHH signaling pathway. Genomic contextual analysis of bacterial SUFU versions revealed that they are immunity proteins against diverse nuclease toxins in polymorphic toxin systems.	0.000194489
NZ_CP022098.1\|WP_095983823.1\|664208_665594_-\|ferritin-like-domain-containing-protein	gnl\|CDD\|153097	cd00657, Ferritin_like, Ferritin-like superfamily of diiron-containing four-helix-bundle proteins. Ferritin-like, diiron-carboxylate proteins participate in a range of functions including iron regulation, mono-oxygenation, and reactive radical production. These proteins are characterized by the fact that they catalyze dioxygen-dependent oxidation-hydroxylation reactions within diiron centers; one exception is manganese catalase, which catalyzes peroxide-dependent oxidation-reduction within a dimanganese center. Diiron-carboxylate proteins are further characterized by the presence of duplicate metal ligands, glutamates and histidines (ExxH) and two additional glutamates within a four-helix bundle. Outside of these conserved residues there is little obvious homology. Members include bacterioferritin, ferritin, rubrerythrin, aromatic and alkene monooxygenase hydroxylases (AAMH), ribonucleotide reductase R2 (RNRR2), acyl-ACP-desaturases (Acyl_ACP_Desat), manganese (Mn) catalases, demethoxyubiquinone hydroxylases (DMQH), DNA protecting proteins (DPS), and ubiquinol oxidases (AOX), and the aerobic cyclase system, Fe-containing subunit (ACSF).	1.9423e-06
NZ_CP022098.1\|WP_095983814.1\|650326_650953_+\|TonB-family-protein	gnl\|CDD\|367555	pfam03544, TonB_C, Gram-negative bacterial TonB protein C-terminal. The TonB_C domain is the well-characterized C-terminal region of the TonB receptor molecule. This protein is bound to an inner membrane-bound protein ExbB via a globular domain and has a flexible middle region that is likely to help in positioning the C-terminal domain into the iron-transporter barrel in the outer membrane. TonB_C interacts with the N-terminal TonB box of the outer membrane transporter that binds the Fe3+-siderophore complex. The barrel of the transporter, consisting of 22 beta-sheets and an inside plug, binds the iron complex in the barrel entrance.	1.61975e-09
NZ_CP022098.1\|WP_095983825.1\|667550_668312_+\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|187608	cd05350, SDR_c6, classical (c) SDR, subgroup 6. These proteins are members of the classical SDR family, with a canonical active site tetrad and a fairly well conserved typical Gly-rich NAD-binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	2.90018e-87
NZ_CP022098.1\|WP_095983819.1\|657122_658817_+\|GAF-domain-containing-hybrid-sensor-histidine-kinase/response-regulator	gnl\|CDD\|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	3.31282e-59
NZ_CP022098.1\|WP_095983818.1\|655422_656565_-\|response-regulator	gnl\|CDD\|274060	TIGR02266, gmx_TIGR02266, Myxococcus xanthus paralogous domain TIGR02266. This domain is related to Type IV pilus assembly protein PilZ (pfam07238). It is found in at least 12 copies in Myxococcus xanthus DK 1622.	8.89212e-17
NZ_CP022098.1\|WP_095991761.1\|650959_652012_-\|chemotaxis-response-regulator-protein-glutamate-methylesterase	gnl\|CDD\|234828	PRK00742, PRK00742, chemotaxis-specific protein-glutamate methyltransferase CheB.	1.42417e-154
NZ_CP022098.1\|WP_095983828.1\|670415_674576_+\|HEAT-repeat-domain-containing-protein	gnl\|CDD\|379311	pfam13646, HEAT_2, HEAT repeats. This family includes multiple HEAT repeats.	9.24453e-10
NZ_CP022098.1\|WP_095983827.1\|669103_669562_+\|group-II-truncated-hemoglobin	gnl\|CDD\|381282	cd14773, TrHb2_PhHbO-like_O, Truncated hemoglobins, group 2 (O); Pseudoalteromonas haloplanktis PhHbO like. The M- and S families exhibit the canonical secondary structure of hemoglobins, a 3-over-3 alpha-helical sandwich structure (3/3 Mb-fold), built by eight alpha-helical segments. Truncated hemoglobins (TrHbs, 2/2Hb, or 2/2 globins) or the T family globins adopt a 2-on-2 alpha-helical sandwich structure, resulting from extensive and complex modifications of the canonical 3-on-3 alpha-helical sandwich that are distributed throughout the whole protein molecule. TrHbs are classified into three main groups based on their structural properties and named after Mycobacterium sp. genes glbN, glbO, and glbP: TrHb1s (N), TrHb2s (O) and TrHb3s (P). TrHb2's belonging to this group include Pseudoalteromonas haloplanktis PhHbO (encoded by the PSHAa0030 gene) which appears to be involved in oxidative and nitrosative stress resistance.	2.26833e-43
NZ_CP022098.1\|WP_095983820.1\|658857_659316_-\|response-regulator	gnl\|CDD\|381108	cd17557, REC_Rcp-like, phosphoacceptor receiver (REC) domain of cyanobacterial phytochrome response regulator Rcp and similar domains. This family is composed of response regulators (RRs) that are members of phytochrome-associated, light-sensing two-component signal transduction pathways such as Synechocystis sp. Rcp1, Tolypothrix sp. RcpA, and Agrobacterium tumefaciens bacteriophytochrome response regulator AtBRR. They are stand-alone RRs containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. Also included in this family us Methanosaeta harundinacea methanogenesis regulatory protein FilR2, also a stand-alone RR. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.56881e-62
NZ_CP022098.1\|WP_095983816.1\|652707_654357_-\|chemotaxis-protein-CheA	gnl\|CDD\|223716	COG0643, CheA, Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms].	1.49926e-141
NZ_CP022098.1\|WP_095983830.1\|676086_676410_-\|hypothetical-protein	gnl\|CDD\|379603	pfam14412, AHH, A nuclease family of the HNH/ENDO VII superfamily with conserved AHH. AHH is a predicted nuclease of the HNH/ENDO VII superfamily of the treble clef fold. The name is derived from the conserved motif, AHH. It is found in bacterial polymorphic toxin systems and functions as a toxin module. Like WHH and LHH, the AHH nuclease contains 4 conserved histidines of which, the first one is predicted to bind a metal-ion and the other three ones are involved in activation of a water molecule for hydrolysis.	1.11457e-24

>NZ_CP022098.1|WP_095983821.1|659308_660943_-|PAS-domain-containing-sensor-histidine-kinase
MTIPSFTMTSPDEMATLLFQVEYLDMLRAILDSASEGMSVVDTTGRRLYMNEQCHKLLGISPTDPAPDDWSEEYGLFLPDTRTLCPSERLPMHRAFQTEEAAEEELFVRNRAIPEGRYIHVSARPIRDRQGKHLGAVLYVRDIHEQRLAEAERRRTELRFQRIVEAAQEGLWMIDGARRVTYVNRFAAELLGYTPEEIIGRDLYEFLGQEEVRRTQETIEVQRQGQTVLINEFKMLHKDGTHIWTMISTCPLNDEGGSYEGSLAIVIDIRHRREAEQQVHQLNAQLERRIAERTAQLEFSNRELEAFAYSVAHDLRTPLRSISNFTLALTEDCADKLDATGLDYVQRIRAASRRMADLIDGILSLSRVNRTEFIETDVDLSTLAHTIREQLQRWQPQRTARFHIQEGLVDRGDAQLLGAMLENLLGNAWKFSRGREVAEIEFGTLPPREGPRVYFVRDNGDGFDMEYQKKLFGVFQRLHTQQEFEGNGVGLATVQRIIQRHGGDVWGEGRVGQGATFYFTLHAPAGQHASRPPAPESPRTPPHV
>NZ_CP022098.1|WP_095983820.1|658857_659316_-|response-regulator
MYDPSQRIILLVEDNADDELMTLRAFRKSNIHNPVVVVRDGAEAIDYLFIQGKHANRNPDIRPQVILLDLHLPRIDGLEVLRRIRAHEQTRTLPVVVLTSSKEERDLVDSYQLGVNSFVHKPVDVTSFFEAVRQLGMYWLVLNEMPLPRRGP
>NZ_CP022098.1|WP_095983819.1|657122_658817_+|GAF-domain-containing-hybrid-sensor-histidine-kinase/response-regulator
MQNRLLELVARGTPLPEMLHSITRAIELLSPGMMASVLLLDDAGLLHVGAGASLPPAYNAVVEGLAIGPTVGSCGAAAYSKRMVVVTDISTHPNWAPYRDKIKEFRLQACWSGPILSSEGQVLGTLAMYYNEPRAPTEHELHLIETMAHIASVAMEKAKAEQERERLLVRERLARHEAEAASRMKDEFLSTLSHELRTPLTSILGWAQLLRTREMSEDKRQRALETIERNARAQTQLIEELLDISRIVTGKMRLDVHPVEPLPVLEAALDAVRPAADARGVRLALRVAPGMGPLLVDAERLQQVVWNLLTNAIKFTPSGGQVVVRLERGEGEARLEVEDTGQGIDPAFLPHVFERFRQADSSTTRTHGGLGLGLAIVRHVVEMHGGSVSAYSEGPGRGSTFRVVLPSTQSGVPAPLSAPRARPARGTGPPAAEAPSLEGVRVLLVEDAPDTRALLTEMLEGSRAQVMCAASAQEALALLLGPLRADVLISDIGMAGGDGYELIRRLRARERAGERLPAVALTAFARSEDRWRALAEGFDMHVAKPVNASRLLSVVASLVSTRPA
>NZ_CP022098.1|WP_095983818.1|655422_656565_-|response-regulator
MSASGGVILIENANPLRAQTIQAIQAADRECVAVGDLTEALAESRRQRPLMLMLDCSSFMPAEESTLSRLQELRRMVGAPLVLLANLETPTEFIESLSQMGADDCLLKPLRQHQLQPRFEVAATPTPRVNPSSLGRLGPKVVSLLHGQQNFAWRTGELLEQSGYHVLYGSLEDEREPPPGSNIELHILCAASREELSRVLRLRHPEETWAGSRWFLICPGGPGELATHSGGGLVAGFDMTQVFPEHVVQKANAWFSRVSNALQPEARVPFFCPVEYREAGNLFGDWNSCYSYDLSPGGIFLRTLVPARPGAAVELKIHLTTQRTELRGSGVVAWANTYAQRKAFSHPVGMGVQFLGMSPKGLSLLRELCGVDPAARNKPE
>NZ_CP022098.1|WP_095991762.1|655021_655393_-|response-regulator
MTRKKILLVDDSNTVLLMHRMMLSGGGYELLIARNGVEAVDLALRERPDLIFMDVVMPQMDGLQACRRIRASPEMHATPIIMVTTRGEPHSVQAGYESGCTEYITKPFDKGDLLQKLRQHLGE
>NZ_CP022098.1|WP_095983817.1|654340_655000_-|GAF-domain-containing-protein
MSQDPPSKPATPDPTALQRTEERLGELRAENASLRTRLDALHQERARLEERLCEADARVTSLVGLYAASHRLHETLERRALLDILRDIINNIVGSEELGIFELDEQHSTLVLVHSMGIEPAGLQSIPLGSGIIGQTALTGQLFVASEGKRPPATGNEPALTACVPLRIGSRVWGVIAIFGMLPHKPTLGDSDLELFALLEKQAGLVLAASETEPDGHRS
>NZ_CP022098.1|WP_095983816.1|652707_654357_-|chemotaxis-protein-CheA
MDIDRDELLKVFVLECDEVFALMEEQLVGLEQQPDPERLRTIFRAAHTLKGNATCVELPAFVEFTHELEDLLERLHTGELAVSHGLVSLLLSAVDAMRQLRGQLAAGQVTLTAQHRAVMALMTRWGRAELTAPVPAASETESSPPPSPSERKPLAEEERARNLRVGITKLDRMVDLIGELSIAQGKLTAMLEGDRPREQLLEASHDGERLLRELQELVMNVRMVPLGPTFRQYVRTVRDLAASRDKHVELVFEGEDVEMDTALVENVRDPLLHMIRNAIDHGIETPDIRRARGKPELSQLKLRAAHDAGGILLEVIDDGAGLNKERIIERARALGLSREPESLPEAELFSFIFEPGFSTARELTATSGRGVGMDVVRRNVEALRGKVTVQSREGHGVTISLRLPLTFAIIEGFLVGVGAETYVVPLESVHECIELPESARGRAGERDGVLNLRGEVIPYLRLRHLFSPGTQAPPRESMVIVQHPQGKVGLVVDMLHGERQTVIKPLGSLFKDLPCISGASILGNGRIALILDDAALLREATRARRSAAS
>NZ_CP022098.1|WP_157758202.1|652189_652564_-|hypothetical-protein
MAQRMDVRVGMVVKSRDGHQMGRVIGLLEDAFVVEKGVLYARDYRVPFRAVERIEDEDIHLVLDKDQMHKASLGEVLEASIGNGLTLGPQALSEARMNITSFQDRDASDVRSEAEKDEEAAHHP
>NZ_CP022098.1|WP_095991761.1|650959_652012_-|chemotaxis-response-regulator-protein-glutamate-methylesterase
MLRVLVVDDSAVVRQGMLMLLKHVPDMVAEVASDPLIARQKMTSHRPDVILLDLEMPRMDGLTFLRELMREEAPVPVVVCSGLAGPGTELAVRALEEGAVEIISKPPLGVGEFLRESRMRFVQSLRDAAKARPRPERYVPPARGEQEPAEKPMASLLTVTTDKVVAVGASTGGTDALRQLLQPMPPDCPGIVIVQHMPEQFTLAFAQRLNELCRIEVKEAEQGDRVLQGRALIAPGNRHLRVRRTGGHYQVEVADGKRVSGHKPSVDVLFHSVARAAGANAVGVLLTGMGEDGAEGLLLMKQAGAATIAQDEASSVVFGMPRAAIERGAADQVLPLKAINEAIRRRARQG
>NZ_CP022098.1|WP_095983814.1|650326_650953_+|TonB-family-protein
MIGSVLSVKSRLALFGLLAAVVSLGGIGCATASRATIAAPPAPEPIAEPAPAPTPEPPPAPAPVVKAERPKASKRTAARPASEAKAATGTSMAARASEPRRPPSDGVSLGSGEPVAFDPSVMTRPQRVSGREPQLTPEAQAERVRGAALVRCVATREGRVTNCRLLKGLPYMNQELLEALSTWRVTPATAQGKPIDVDYTFVVRIPTG
>NZ_CP022098.1|WP_095983823.1|664208_665594_-|ferritin-like-domain-containing-protein
MHSPPLRLLFARTLRASLLSPLVLTGCGVIEPPAGGPCGEPHQEQCPGVDLTGYARPTCDQNALAVSGLSPAVAPDVVQLRVVGTKFNSGTFPQRVVSTSGTACATASDPSACQSALEQLGSTQGFHEHCEQVCSAYYLATTRGDEVTAHTSLEALKSFLRPIDTTQEAALLAFGQGLNVSCGNLTSGAVKANPDGSFNVVGTEGSTCGAGTNLYQIVMKVSPSGDLTEEKRTLLQKGDPNCIVGRRPDGLHAAASVDCDSALGRHFAHAAHMEAASIQAFLRLREELALHGADESLRNDALASALDEVMHTDVSTRLARRFGATPPRLQVETPPPRSLFEVALENIVEGCTRETYGALVAHYQAMHARDEEIRGVMARIAEDETRHAELSWAIDHWAHERLSDAERATLREARRQAVQTLREELAHPLDAQLIDEAGLPPPEVAASMLASLERELWAGHP
>NZ_CP022098.1|WP_095983824.1|665903_666662_+|hypothetical-protein
MNAVRATLLSACVLLSTGGAAHAQTRPPPDIAQPGTPVPTSPLFPSSTVGDLLTRHLNLMVSVGEEVESRYQESLRLIQKEPEAVRLLQDAYAKTVETEYFLRWQLVYTLASLNQREALSGLVRIALSTIPAERGGSDEFFTTGQESNIRVAAVDGLASLAKLGVTEAGSYLLRLSQHSDLSIRQRAVRGYLAAGSDYDARAKLLQANLPTSDHWLITLRVTEVRGVAHPDDTPEDMRPRKRESDDESPIAR
>NZ_CP022098.1|WP_095991763.1|666736_667444_+|hypothetical-protein
MTSLSARAATCYYQPGNNTTSGDVFYGAFTCNQKYIDQFWNHFDFDKGDWDDGFGYEAACDLNRPLARTFNALYLLAYSAEDYARSTSDFSGNALRWAYPYSSTYIDELDGRCGSGDKNTGARATTVHGPIIDNYTELYWPFFYGENVVQRAGTILHESRHGAGKSHDAGSSCPRGASCDSSWGYKGANMYQVLYLWWFRVDGTRTTQAMRDFARTEAQNIINNGFKANPGFVIP
>NZ_CP022098.1|WP_095983825.1|667550_668312_+|SDR-family-NAD(P)-dependent-oxidoreductase
MAEMSYRTALVTGASSGLGRGLALWLGKRGVKVYAAARRLPRLETLAQEGKALGATLEPVELDVSQADATLARVRELDEACGGLDLVVANAGVGFPTNARDFPWEDAKRVIDVNVTGAAATLSAVLPRMVERDRGHLVGISSLASCRGLPQNAAYSASKAFLDTFLESLRVDLHGTGVRVTCIRPGFVKTEITAGIQHPMPFLLEADPAVEHMGQAILRGEDVYGFPWPMARAVGMARWVPNALFDAVASKVL
>NZ_CP022098.1|WP_095983826.1|668330_668915_-|hypothetical-protein
MRRATSLGSLVVLLWAGTSEAGPWRGYASLSAGFVIDHTSGIGARGGGLQAYVGVETPFGLSLGVVGEGVETWGRRFQGQTTELDYLSLGGELRLRFLRDGNVTPWVGLRVAQSRATPLTLTDLGTGSPQRMLHSGLSTAVRLGVDAWVGDHLGITASTAWQWCDVRVDSLESATAEACAKPLHSILLGPTLRF
>NZ_CP022098.1|WP_095983827.1|669103_669562_+|group-II-truncated-hemoglobin
MSIEMKPIGLNIPDADDDWIPRMEDMPFHRLGGEAGVRALAEAFYDAMDANEPELARLHELDANGKVGPGTRERFGLFLIGWLGGPQHYMEKHGHPRLRMRHGHLPVNLAHRDAWVRSMQRALDARGVKGGVRRFLDQRFAEVADFLRNTEG
>NZ_CP022098.1|WP_095983828.1|670415_674576_+|HEAT-repeat-domain-containing-protein
MGSEGRGENDTLENEGLPAYIGYEYQIFVTVWVALELIFKRGLPHIEIEPASQEDIEANLRVNPDEASAVLRVETLSIQVKFRGSEWKPAAFRELLQGKPKTKKGKQGPAPRQRAWEFLGADPLRRYLLITNAQLAPKLQSLRVEELFSQPGNAVMPEECTEGDGGQELAKRIAVLAEQPLELVAFKAKEFLTYRLHVPSTRAEECLRRLIESVRNRLLGIGSRRWTRGEILAEAQRFGGSLYPTPALDTFVPPKHIRQIEQQLANKHVVVLIGQAGAGKTLTAQFLEYKLSTPEGPEQEQQTPFMICRAKVPQDARRELASPGSVLFIIEDPWGKSKLSVDADQWVSELGSFLRQAGEQKKFIITSRQSILEDAEGMEDVEDFCVRIDYEHYDEGARRRILTNMLRDAQPWQRQLALESATRIVNQLEAPISLQRFAEQLKKAKSSENVVLSRLIQASGVNVLADLVEREIGLLTWEAVPAAAVLWSLLCETPTFSRAAMEQRGSLARRVAPPFAPYLEVSRLALWMAGERWLDSDDATYRAHPTTIQGLEQLIKGKRADMARGVLEPLLSGLVAVSQFADALGIAENLRDRQDWIPADVRSAIANSLREQLLADDGEERFRDTFFKAVRWSNGRDPVSLMVQALAAESKPVKKASFAIREWHRPTWTTAERESVLASKEARRIVERHIRYVVPYHSEIFVGVLDRPRWLSELWNLSTVYPDAVVVAVEEQADGVRELALGAMLTDRASFDSLADKLLRGLDEVERDAKAHRQEVARGMAPPGARAQDADEYFSERAYPYSSALEELVAERRRVEGYEWLVKHAWRARLLGNWGAALQREDEGLTKEEMLAFFAACQPEELSRVARTIHGKQWSLIAPELVAALGEVKQDDLEEYLGAVARVVSPEQLKALIKANPPPLSDVQRAAIVLSSRSAHGPLEEQALALQKMLASTLVPDREVLLDCCERAERGEELGASQLPPLRPEDLRTLQEWAAEPAFIPSRGALVMLAAVGEPVLELVRPALSHPDERARLAAVRALALHPEGEARQLLRRALEDSYFACREQALRALASSATPDERRELLRLARKEPSDMVRLAYVEAIRQHHWLDGVDVLCEFLRDETDWSDDPYGDEVGHRIAREAARVLTTLSGELPQDVISQLLEFVRGGVASNSDPFVHDLVCKFLEALAVAELPSVLIHVAGSPKSSKRQWAQRSIRINALLVLHRLVQKQPTEQLDLIQPLVELAKHRNPWLSGLAVIMLGLLAPRSWESSEPIFAESEEQREAKAFLMLCAASTRGLNFQGIAAAKALPVAHPASQIVEWLSASLPKSADEWRERLDAHQETRDWLWVLQSGEGWEDFLWRACCHFLGDEFERSFKPRDLAPSTT
>NZ_CP022098.1|WP_095983829.1|674825_676073_-|hypothetical-protein
MPNRYFDLSDDVYVPGRWDLDTPTDAQGREVDDYVFTKGAPTTIEGRLRIPFRGGDGKALDYSEAGIGVPLVSARVAAVFAELAPRDVQLIPVDVEAHAEQFYILVCTRVVKCIDDEASDEVRYWKPEDGRPEKTGRYRSVIGMRIDPTKVGDAKVFRSWGWDVVLIISEDIKQALERVGATGAKFTEVTGPSTISAEERARDQKSRELFEQADTAREAAWRTLGSLDKEVFMPIAMSGAWPGHRQLWSVIRREAGRTLLVTHGLSDPFIERLEPSVGFGLELAMEVDAAVKDISKGWPLLLLNRVADEVAEHEHVRKRVKAGIFSMEVSGKGLPKSLVTEEGRVAVLLGVTSRTLPGHFSTPYGQVKLVTVKALLPSELAYLLEHGAEGQAELARRFAESGEEHLSRLRRKPVA
>NZ_CP022098.1|WP_095983830.1|676086_676410_-|hypothetical-protein
MHHIATVENSKSTARGGPWTQRFQELFDKAGMSMEAQANKVPLEGHKGPHPQAYHEAVYRRLRDATSTCRSTLDCRKALVTELRQMAQELTDRSSKLYKLLSEDARR
>NZ_CP022098.1|WP_157758203.1|676462_676786_-|hypothetical-protein
MSLEVLLELVSGDVVGMKRHQEVLRTLLSSPAGEWRDLRRLDPTDALAAECQNYSPDVGPRVLEGLRLAWTPHPDEPSDSPYCLILFFYGRDGLIWHSLAIFNRDTL

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_6

742490-742620

Orphan

Consensus_repeat	Method
CTGCTGCTCCGGCCACCACCGTTGTCACTGTTGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022098_6

>merge|NZ_CP022098|6|742490-742620|CRISPRCasFinder
CCGTTGCCCCGGCCACCGCCGTTGTCGCCGCTGCTGCTCCGGCCACCACCGTTGTCACTGTTGCCGCCGCGGCCCCAGCCGCCACTGCTGCCGCCACTGCTGCTCCGGCCACCACCGTTGTCGCTGTTGCC

>NZ_CP022098|6|6|742490-742620|CRISPRCasFinder
CCGTTGCCCCGGCCACCGCCGTTGTCGCCGCTGCT	GCTCCGGCCACCACCGTTGTCACTGTTGCCGCCGCGGCCCCAGCCGCCACTGCTGCCGCCA
CTGCTGCTCCGGCCACCACCGTTGTCGCTGTTGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_095983881.1\|751710_754611_+\|isoleucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235588
NZ_CP022098.1\|WP_095983869.1\|735393_737607_+\|HYR-domain-containing-protein	unknown	unknown	gnl\|CDD\|200169
NZ_CP022098.1\|WP_095983875.1\|745538_746984_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NZ_CP022098.1\|WP_095991768.1\|737638_738373_-\|metallophosphatase	unknown	unknown	gnl\|CDD\|277339
NZ_CP022098.1\|WP_157758210.1\|754607_755069_+\|DUF4430-domain-containing-protein	unknown	unknown	gnl\|CDD\|379618
NZ_CP022098.1\|WP_095991769.1\|741452_742268_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095983873.1\|743614_744286_-\|DsbA-family-protein	unknown	unknown	gnl\|CDD\|225355
NZ_CP022098.1\|WP_095983865.1\|725005_727162_-\|glucuronyl-hydrolase	unknown	unknown	gnl\|CDD\|369381
NZ_CP022098.1\|WP_095983874.1\|744438_745470_-\|RimK-family-alpha-L-glutamate-ligase	unknown	unknown	gnl\|CDD\|182468
NZ_CP022098.1\|WP_095983867.1\|731226_733122_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|223504
NZ_CP022098.1\|WP_095983866.1\|728036_731021_-\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|223715
NZ_CP022098.1\|WP_095983870.1\|738683_740297_+\|transglycosylase-SLT-domain-containing-protein	unknown	unknown	gnl\|CDD\|271154
NZ_CP022098.1\|WP_095983877.1\|747933_749505_+\|pilus-assembly-protein	unknown	unknown	gnl\|CDD\|379164
NZ_CP022098.1\|WP_095983879.1\|750493_751258_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095983878.1\|749504_750494_+\|pilus-assembly-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_157758209.1\|727333_727471_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|176245
NZ_CP022098.1\|WP_095983876.1\|747148_747907_+\|pilus-assembly-protein	unknown	unknown	gnl\|CDD\|377921
NZ_CP022098.1\|WP_095983871.1\|740363_741434_+\|tolB-protein-precursor-protein	unknown	unknown	gnl\|CDD\|274305
NZ_CP022098.1\|WP_095983880.1\|751295_751586_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369225
NZ_CP022098.1\|WP_095983868.1\|733359_735291_+\|potassium-transporter-Kup	unknown	unknown	gnl\|CDD\|225700

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095983881.1\|751710_754611_+\|isoleucine--tRNA-ligase	gnl\|CDD\|235588	PRK05743, ileS, isoleucyl-tRNA synthetase; Reviewed.	0
NZ_CP022098.1\|WP_095983869.1\|735393_737607_+\|HYR-domain-containing-protein	gnl\|CDD\|200169	TIGR02232, myxo_disulf_rpt, Myxococcus cysteine-rich repeat. This model represents a sequence region shared between several proteins of Myxococcus xanthus DK 1622 and some eukaryotic proteins that include human pappalysin-1 (SP\|Q13219). The region of about 40 amino acids contains several conserved Cys residues presumed to form disulfide bonds. The region appears in up to 13 repeats in Myxococcus.	5.09752e-08
NZ_CP022098.1\|WP_095983875.1\|745538_746984_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	1.55537e-128
NZ_CP022098.1\|WP_095991768.1\|737638_738373_-\|metallophosphatase	gnl\|CDD\|277339	cd07393, MPP_DR1119, Deinococcus radiodurans DR1119 and related proteins, metallophosphatase domain. DR1119 is an uncharacterized Deinococcus radiodurans protein with a metallophosphatase domain. The domain present in members of this family belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	7.30122e-55
NZ_CP022098.1\|WP_157758210.1\|754607_755069_+\|DUF4430-domain-containing-protein	gnl\|CDD\|379618	pfam14478, DUF4430, Domain of unknown function (DUF4430). Although this family has overlaps with SLBB, the majority of its sequences are unique. Several family members, eg UniProtKB:A0RGA8, that do not overlap have an LPXTG-cell wall anchor at their C-terminus, a SSF_Family 10_polysaccharide_lyase or Glycosyltransferase structure associated with them in the middle region, as shown by InterPro, as well as this domain at the N-terminus.	7.26777e-11
NZ_CP022098.1\|WP_095983873.1\|743614_744286_-\|DsbA-family-protein	gnl\|CDD\|225355	COG2761, FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism].	2.68944e-28
NZ_CP022098.1\|WP_095983865.1\|725005_727162_-\|glucuronyl-hydrolase	gnl\|CDD\|369381	pfam07470, Glyco_hydro_88, Glycosyl Hydrolase Family 88. Unsaturated glucuronyl hydrolase catalyzes the hydrolytic release of unsaturated glucuronic acids from oligosaccharides (EC:3.2.1.-) produced by the reactions of polysaccharide lyases.	3.27675e-17
NZ_CP022098.1\|WP_095983874.1\|744438_745470_-\|RimK-family-alpha-L-glutamate-ligase	gnl\|CDD\|182468	PRK10446, PRK10446, 30S ribosomal protein S6--L-glutamate ligase.	2.46808e-95
NZ_CP022098.1\|WP_095983867.1\|731226_733122_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|223504	COG0427, ACH1, Acetyl-CoA hydrolase [Energy production and conversion].	2.15169e-111
NZ_CP022098.1\|WP_095983866.1\|728036_731021_-\|PAS-domain-S-box-protein	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	5.67368e-53
NZ_CP022098.1\|WP_095983870.1\|738683_740297_+\|transglycosylase-SLT-domain-containing-protein	gnl\|CDD\|271154	cd14488, CBM6-CBM35-CBM36_like_2, uncharacterized members of the carbohydrate binding module 6 (CBM6) and CBM35_like superfamily. Carbohydrate binding module family 6 (CBM6, family 6 CBM), also known as cellulose binding domain family VI (CBD VI), and related CBMs (CBM35 and CBM36). These are non-catalytic carbohydrate binding domains found in a range of enzymes that display activities against a diverse range of carbohydrate targets, including mannan, xylan, beta-glucans, cellulose, agarose, and arabinans. These domains facilitate the strong binding of the appended catalytic modules to their dedicated, insoluble substrates. Many of these CBMs are associated with glycoside hydrolase (GH) domains. CBM6 is an unusual CBM as it represents a chimera of two distinct binding sites with different modes of binding: binding site I within the loop regions and binding site II on the concave face of the beta-sandwich fold. CBM36s are calcium-dependent xylan binding domains. CBM35s display conserved specificity through extensive sequence similarity, but divergent function through their appended catalytic modules.	6.371e-43
NZ_CP022098.1\|WP_095983877.1\|747933_749505_+\|pilus-assembly-protein	gnl\|CDD\|379164	pfam13400, Tad, Putative Flp pilus-assembly TadE/G-like. This is an N-terminal domain on a family of putative Flp pilus-assembly proteins. The exact function is not known. The Flp-pilus biogenesis genes include the Tad genes, and some members of this family are putatively assigned as being TadG.	0.00162291
NZ_CP022098.1\|WP_157758209.1\|727333_727471_-\|hypothetical-protein	gnl\|CDD\|176245	cd08285, NADP_ADH, NADP(H)-dependent alcohol dehydrogenases. This group is predominated by atypical alcohol dehydrogenases; they exist as tetramers and exhibit specificity for NADP(H) as a cofactor in the interconversion of alcohols and aldehydes, or ketones. Like other zinc-dependent alcohol dehydrogenases (ADH) of the medium chain alcohol dehydrogenase/reductase family (MDR), tetrameric ADHs have a catalytic zinc that resides between the catalytic and NAD(H)binding domains; however, they do not have and a structural zinc in a lobe of the catalytic domain. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit.	8.9675e-12
NZ_CP022098.1\|WP_095983876.1\|747148_747907_+\|pilus-assembly-protein	gnl\|CDD\|377921	pfam07811, TadE, TadE-like protein. The members of this family are similar to a region of the protein product of the bacterial tadE locus. In various bacterial species, the tad locus is closely linked to flp-like genes, which encode proteins required for the production of pili involved in adherence to surfaces. It is thought that the tad loci encode proteins that act to assemble or export an Flp pilus in various bacteria. All tad loci but TadA have putative transmembrane regions, and in fact the region in question is this family has a high proportion of hydrophobic amino acid residues.	6.74548e-08
NZ_CP022098.1\|WP_095983868.1\|733359_735291_+\|potassium-transporter-Kup	gnl\|CDD\|225700	COG3158, Kup, K+ transporter [Inorganic ion transport and metabolism].	0
NZ_CP022098.1\|WP_095983880.1\|751295_751586_-\|hypothetical-protein	gnl\|CDD\|369225	pfam07137, VDE, VDE lipocalin domain. This family represents a conserved region approximately 150 residues long within plant violaxanthin de-epoxidase (VDE). In higher plants, violaxanthin de-epoxidase forms part of a conserved system that dissipates excess energy as heat in the light-harvesting complexes of photosystem II (PSII), thus protecting them from photo-inhibitory damage.	0.00268008
NZ_CP022098.1\|WP_095983871.1\|740363_741434_+\|tolB-protein-precursor-protein	gnl\|CDD\|274305	TIGR02800, Protein_TolB, tol-pal system beta propeller repeat protein TolB. Members of this protein family are the TolB periplasmic protein of Gram-negative bacteria. TolB is part of the Tol-Pal (peptidoglycan-associated lipoprotein) multiprotein complex, comprising five envelope proteins, TolQ, TolR, TolA, TolB and Pal, which form two complexes. The TolQ, TolR and TolA inner-membrane proteins interact via their transmembrane domains. The {beta}-propeller domain of the periplasmic protein TolB is responsible for its interaction with Pal. TolB also interacts with the outer-membrane peptidoglycan-associated proteins Lpp and OmpA. TolA undergoes a conformational change in response to changes in the proton-motive force, and interacts with Pal in an energy-dependent manner. The C-terminal periplasmic domain of TolA also interacts with the N-terminal domain of TolB. The Tol-PAL system is required for bacterial outer membrane integrity. E. coli TolB is involved in the tonB-independent uptake of group A colicins (colicins A, E1, E2, E3 and K), and is necessary for the colicins to reach their respective targets after initial binding to the bacteria. It is also involved in uptake of filamentous DNA. Study of its structure suggest that the TolB protein might be involved in the recycling of peptidoglycan or in its covalent linking with lipoproteins. The Tol-Pal system is also implicated in pathogenesis of E. coli, Haemophilus ducreyi , Salmonella enterica and Vibrio cholerae, but the mechanism(s) is unclear. [Transport and binding proteins, Other, Cellular processes, Pathogenesis].	8.05532e-49

>NZ_CP022098.1|WP_095991769.1|741452_742268_-|hypothetical-protein
MGLLPTACSSGGAPDPNGNRSTQVDLDHLTITVSGRAELLPEAAHLLDAQGQRLPALDGLTVTLEEPWGMGVNDENAVLGEGLLGEDHAFSVSDVLVRGIHLSLAARLEHPGLVRSSTVIFDTALARTRPSTDISDTRAWALPEAFEQTLTRSIGEAAIRGHSDQRAGTLRDAGFVLGRIVDASGEPLAGAVVVPDREELASRIYYPSPDFQGAPQDGTSTTGLFVYVHSATAPESFLLSVKGSEDHGHRNVAVTPGTALVLTLSPGNDAR
>NZ_CP022098.1|WP_095983871.1|740363_741434_+|tolB-protein-precursor-protein
MLALALAGCGAGRCGGDASAPMSLEERRALPGVIAFVSERAPQRDVWLVRPSGGESQLTRAPEDEYPVAPSPDGAAMLVVSAAEVGGLHLEQLWLVPLGGGPRVKVTEPRGRARNPSWAPDGSWLVVESDARGFSDVVRQAPRADAEVLELATAREGNFEPSVSPDGTRVVFVSSRDGDPELYVMKADGTDVRRLTHFHREDMVPRWSPDGQWISFLSDREGRTRLYVMKPDGTQLRPVSGSATVGEEREPAWSPDGRKLAFVAASKDTKARIWVVDVAGGEPVALTRGQAVDDQPAWSPEGKHLVFASDRTGDVELFLMRADGSGQTRLTTSQGADWLPRWFIPRKPPSPDAGSP
>NZ_CP022098.1|WP_095983870.1|738683_740297_+|transglycosylase-SLT-domain-containing-protein
MRPFRPPMVAAVAALCLSACGPQDAVEGAAGSAVEDSRTPEQREAQRTPHELNEAFTRAANDFQVPADLLKAIAYTETRFEMISGQQEFEGMPAAHGLMALRGEKLAEGARLAGVTEEAARTRPEENIRAAAALLSSYAAEAGLDRSDVGAWAPVVVKLSGITNPEAQAEYVHRDVYGVMRKGVVAQTPEGRVAVSLMPSEVAARFASPSVRAMLAGKDYASAVWRPSPNYGSRPTGAQGDVQMIVIHTCEGTYSSCWSWLTNSASGVSAHYVVKEDGGEISQLVSEADRGWHVGASYDPSLNGGTLGSLKDVSVNHFSVGIEHGGSASQSSFPTGQIDASAKLSCDISKRQAIPIDSYHIVAHGKLQPATRTDPGPNWPWSTYLSKVKSACGSTDTSSIIVDSNNANNDTVNKGYIEVSGNWVSTSTTGGYYGSGYFYAETAAVSDPATFYFYLPAAGSRTISAWWTAGSNRSAAAPFIIYAGSTKLATVNKDQQTGGGTWNTLGTWSFPAGWNKVQLSRWAADGYVVIADAIRVQ
>NZ_CP022098.1|WP_095991768.1|737638_738373_-|metallophosphatase
MRLFAIGDTHLPSTRNKDMHRFGWTDHPLPLQRAWDEKVRPEDVVLVVGDISWATRPHEVLDDLKWLDERPGRKVLVRGNHDYWWGDSASKLRKLLEPYKTVEGFLHNSSVIIGRWVIAGTRLWTAPEAPPMPGGEMGDESGDAGYVERETRRLMTSIAEAEKKEKESPTPLTRVVAVHFPPIYANEKPTAFLGPIEAYKPKVCVYGHLHAGGIPAGFTGERAGIRYVLASCDAAGFSPLLLDE
>NZ_CP022098.1|WP_095983869.1|735393_737607_+|HYR-domain-containing-protein
MCPMPPPPSPRRSSGACVRLGLSLCLLSWLSLGTACVSYSWEDEPLVPPRSGPTPPGGLPSTGNPSTPQPAPPTPGKTPALGGFVVVTGDDADDLWHCEGSLCGGLFPSLFREALSRSRTGGQGILAIGVNGEQALTAFESWNDPAQGGPGALVTHVRSTEDISRVDFSRYAFVYLPSAQQHTLGGLTARQIGALNERQPDLSRFVNERGGSLIALTQAGVTGGWGFLPLPLTTRDTEFDFAQPTQELTAFAPSLTSAELSHKSFHNVFTGPSGYSGLRVLAVNDEVYHPDKGLPVMLGGSAIVLTAEDCADGRDNDGDGAVDGEDPDCQVCGNGRVDPGEACDDGNTVGGDGCGASCQNENHAPEVTCRDATVCTDPGLCVATSPTGLATATDADGDEISWDTHPLGPYAPGVHGLCVTASDGRKIDSCWSNVTVRDCEAPRFTCPADFTVECSAEGSAPVSPPEVGATDNCGVARVTRPEGGTLPLGTHELVYTATDSAGNTATCAPKVTVVDSRPPSVACPAPITTECTGRNSAWVTPGAAHATDSCTEAALSGPEADFYPLGVNTVRYTARDGSGNEASCTSTIQVVDQTPPTVDVTPPEPLWPVDQKYRTLRLEDCITVYDRCSGGLTQTGATGGITCVSSDEPKGSEPDVVFVDATTVKVRVDREAEGDGRVYSLHFEVRDAAGNVTRGLCPVGVPLERGGAPVHDSGEQWRTCRSEGGAPAWKPLVSKAR
>NZ_CP022098.1|WP_095983868.1|733359_735291_+|potassium-transporter-Kup
MSASPPSLSSVPSVPSVPGAPDSNKRLAALAMAALGIVYGDIGTSPLYALRECFTGEHGVAPTHDNVLGVLSLIFWALIMVVSVKYLVFVMRADNRGEGGILALMALAMQRKRGEEVKVRPVVITFGLFGAALLYGDGLITPAISVLSAVEGLSVATPMFEAYIRPLTILILMGLFLIQRHGTAGIGAIFGPFMLLWFLTLAVLGVKEMVTYPAVLGALSPLHGVNFFLANKGHGFLALGGVFLVVTGGEALYADMGHFGAKPIKLAWFGVVLPSLMLNYMGQGALLLRDPNAARNPFFLLAPDWALYPLVALSTGAAVIAAQALISGAFSITQQAIQLGYSPRLEVVHTSAEERGQIYLPGINLALLVGVILTVLGFKSSTNLAAAYGIAVSTAMSITTVLAYVVARERWNVSRAVALPVAGLFAIMDLSFFSANAVKIAAGGWFPLLLALAVFTLMTTWKRGRDILAQRLRSSSIPLTQLLESFGDHPPVRVSGTAIFMTGNPEGTPPALLHNLKHNKVLHEQVMLLTIASEEVPHVPPEDRVEVIRLEAGFVRVISRHGFMENPSIPEILKRAREKGLQFNLMGTSFFLGRETLIPSKKPGMAMWREALFAWMSRNARSATSYFRIPPNRVVELGAQVEL
>NZ_CP022098.1|WP_095983867.1|731226_733122_+|GNAT-family-N-acetyltransferase
MDPRDWQVRYADKVSTAEEAIRLIPPGRRILIGSGAAEPMTLVQAMVEKGEHLFDNEVVHLLTLGPAPYVEPEHRYRFRHIAFFIGANTRQAVQEGRADFMPVFLSEIPELIRSHRVRVDVALLQVSPPDGHGYVSLGVSVDVVRSAVEAAPLLIAEVNPRMPRTHGDSFVHVSRLHRLVPVDQPLLERPLEPQDEVSREIGGHIARLIPDGATLQLGIGGIPDAVLAQLTHHADLGLHTEMLSDGVMHLVDAGVITGRAKTLLPGKLVTSFIMGTQRLYEWAHDNPAIEMRPSDFTNEPGVIAQNERMVAINGALAVDLTGQVAADTLGGCFFSGIGGQVDFIRGAARSRGGRPIIALPSTAKGGTMSRIQVALEGGTGVVTSRGDVHYVVTEYGVADLWGKDIRERAKALIHIAHPDFRAELMAAAKARHWVLPDQVVPRARYPWTEERVERILSGQELLIRPARITDERAMQELLYGLSDDSTYRRFMGFKKWHPHEEVQQLVNPDFEQNMALVAWVPGTDELVGVVRYDVVPSTGLGDVAFVVRDDWQGKGVGTALMKRIREAAQARGLPGFQADVLVVNKPMLDVFHESGLTVQARLEDGCYHLELLFPGGEASRHAARPTGAVHT
>NZ_CP022098.1|WP_095983866.1|728036_731021_-|PAS-domain-S-box-protein
MLPTPGDRHYSSLMTTSHHRDSLHQLDQALARLVPAASVLAVLVASLDLLGWALGSRFLVRIVPLPEAGIMMPNTAIGFVLSGTALWLLHEEEANRRRRRTGQALALVVMLLGGLTLSEYIFGVDLGIDHLFFSETVKHLAPALPGRPSSMSALSFCLMGLALLVLHVRTRRGWLPTRLLSLAVTLLSAQSLIGYLYLEESLFESERLISTVPPYTPMAVHTALLFLLLSLGILSVHREHGLTGVLLRDDLGGIMARRLLPAAILTPLLVGGVRLLGERLGLYGTTFGVSVFVLITMASFLLVVVRNANALSRLEVQHRNMEQSLRLSEARFAGIVSNAADAIISIDEEQKITLFNTGAERIFGYSTSEALGRPLDLLLPEQFQARHKQYIREFAATGRTARQMGERLPILGRRKSGEEFPAEATISRLELDGTRLLTVILRDITVRKRAEEGLRNSEERFRTAFEDAPIGMALVGLDGLFLNVNGSLCEIVGYSQKELLTKTFQDITWPEDLELDLANARRMRQGELSSYQLEKRYIHKDGHLVTILRTGSLVRDSQGRPLYYIAQIQDISERKQLERAWRFLAEAGPRLAASLEPQTTLATVAGLTVPSLADWCVIDLLGEDGRVQWVESRAASPEKSRVLREMLTAYPHEPLRQGHIVADVLRTGQPALLPQIPEAVLEATAEDARHQELLHRLEPRSGIVVPLVARGRILGAVILTASESGRRYGARDLALAEELARRAALAIDNARLHEKSEQATRTRDEVLRIVAHDLRTPLNVIALNAGKLLKCPPEKRATDTKPLESIRKAVDRATRLIQDLLDVARMEAGRLSVDREPEQTAPLVKEAAELHRTLVEEKCIQLTVTVPEDAPSVFADRDRVLQILSNLLGNALKFTPMGGQITLRAEPTGSMVRFSVRDTGSGIAEEDLPHLFEPFWQAPAGRKQGAGLGLAIVKGLVDAHGGHIWVESNPGVGSTFFFTLPTASPAEEHPTHHA
>NZ_CP022098.1|WP_157758209.1|727333_727471_-|hypothetical-protein
MEMVRGKRVDLTPLLTHHYKLDDIRNAYALFGERREGVIKVAIRP
>NZ_CP022098.1|WP_095983865.1|725005_727162_-|glucuronyl-hydrolase
MGEGVKTRHGVCLLFGLCCALAAVPVQAFDEAAASQTLQVVRRKLTRTAAELPVGQYPKSSRPDGTWLLIPADNMIGWTQGFFPGELWLMYDQSREPDWRTRAEAWTQPLEVQQYNVQTHDLGFKFLPSYGLAYRLTNDDYYRQVLLRAAGSLASRYNPRVGIISCCDWNPDWHLPLVVDTMMNLELLLWASRNGGQSGWRDMALNHALRTQADIVRPDGSTYHVVDYDPNTGAQLFRGTYQGYSDTSTWARGHAWAIHGFTLVYRYTRDPRMLEAAQHVTDYYLGRLPEDAIPNWDLDAPTPQKDSSAAAIIASALLELSNYVPDTDKKVAYWNAALRMLDSLGSPAYLDTADTSPGILLHGVGNFPAGQEVDVSLVYGDYYFLEAVRRFQRQTRPPLPSDWYSRFDFAAATHTLGGGNTGLQVAEFDVTPLNHPLDAVIGYADSATSVTAFSQLSMLIRMNTSGLFDVRNGAVYAATNPVPYEALSTYHVRMVTDLGAGQYSVWITPPGGAEILLADRFVFRSGAPPIDDLGQVVLKSGAVDEEYRVSGHTVGGVRSSQPGFAAGTRALGDGNTGVLVAEFDVTPRTRPLDGVIGYADSSARVTSRSALALSLRLSPAGVFDAYDGTRYAATNPVPYEANATYHVRIVADLPAGRYSIWLEPPSGPEVLLADRFAFRAGAPVTDDLGQLTLKSTTAGEFQIAGHTLRPAAGALPAP
>NZ_CP022098.1|WP_095983873.1|743614_744286_-|DsbA-family-protein
MKPSSKPLQITIYQDVLCSWCYLADLRLETLKHEFGDIVRWRVRPYPLRVHDKRPTEKELRGLTQEISLAQKEPEPVARLLSTELWRGGDPPRSSIPALAALEAANLQGPTARAHLARAMQKTALEQGVNVTRTDVIFELATRVGLDMSPFSVAYHSADTRKLILDEHQLAASRGVRGVPTLVIAGRWMVCGLREVSEYREYILGCLSKLYTPRAGSSERVVH
>NZ_CP022098.1|WP_095983874.1|744438_745470_-|RimK-family-alpha-L-glutamate-ligase
MPAKKVSSKKASVQARAKAPPRTVEPRPSSGAAPPPRLPRSKRTVVILSRKRSLYSTRRLVEAIRQRGHRPLVLDTLRCTMVLAPSQPRMLYRGVDIKGVDVVIPRIGASITGYGLAVVAHFEMMGVPVLNGALAISQSRDKLRALQLLCRAGLDAPRTVMAHDRSNMRKLVEEVGGLPVIIKLLRGTQGVGVMIAHTLQEVQTIGSTFWDLGQEVVLQEFVAESKGRDVRALVVGDKVVGAMRRRAKQGEFRSNIHRGGEGSPVELSATYVEVAVRAARLLGLGIAGVDMLEGHHGPRLMELNSSPGFEGLERATGQDIAGEMIDHALALVEARAIATRPTL
>NZ_CP022098.1|WP_095983875.1|745538_746984_+|sigma-54-dependent-Fis-family-transcriptional-regulator
MRTPEPHPDDILTNPGENGLDSVVAPEAGAGAGTEILVLEPRATLKLRKCRVQVTAGPDEGRSIVSDKERLRCGAHPTNDLVLAEDRTASRHHFEILNTERGWLLVDLNSTNGTFLEGRRVERAYLSAGAVVRAGSSVLSFTPIDEEVTVEPDREGELGGLVGQSVHMRQVFALIKKIAPLDVSVIIGGETGTGKELVARAIHERSSRSKGPLVVLDCGAIPPHLIESELFGHEKGAFTGAMAERPGAFERAHGGTIFLDELGELRLDLQPKLLRVLENREVRRVGGNDVLSVDCRVIAATNRDLVKEIAAGHFREDLFFRLSVIHLQLPPLRERREDIPLILSRALADPEVLARHGRKHISPEALALLMAYAWPGNVRELVNVLSHVLAFSEGEEVLPEHLPARVRGQAREVPLPFNEHLTFKDAKEQLLENFEREYITRVLSRCEGNLSRAARESGLHRKSIERLVKKYQLDAKGMKPR
>NZ_CP022098.1|WP_095983876.1|747148_747907_+|pilus-assembly-protein
MTPRVPPNRGQSGQASVEAALSLPLVVFLMLGTLQLFLMLQGRIMAEYAAFRAVRSGSVKHGDCTAMTHAAVLALMPSYHSFMAGGGSPAQKLGQAFGRYKDNVYRTSARGNPVEGALVWILRDSPVAASVPNEDQNFDQADGANRRMEIRLVYWYPLKIPFADWVISRMTLARWGLQDYTAQDPLSPTRRANWTAENPTSLEGAIRDELRRRISIGFYSMPIHASASLRMMTPVRRLHFQTQNCAPAPEVL
>NZ_CP022098.1|WP_095983877.1|747933_749505_+|pilus-assembly-protein
MVLMVISLFLLTLMVTLTLSIGSKVREKMEVQAVADAAAYSNAAVTARVYNEIALLSRAQIAHMVSMAAVQSLISWSTLFRANVAATSLNYSIISAQHAKDAARCCKKYSPCPHLCGCSIAASAVSGLKAFQVWTRDVAESMQFEALDTAAAAQSLRLQDAAMRLHGVQLLEYVRLMGEINNQSMADEIVDAAKGGSRVAGEWSAPGGGDSVSNREIGFFTGATTPIDILNSHHVFAAMGSRGFSFITGRSGIPAMVIQQQLQALGYVVPPDRATVVNQGSSYFSTLPNHGALWPLVNGKYSWTDDHGMNTLRYNHTFMPCRRYQSAFPTMVLLNSTDSTDPTDLHVWSPFFFVDTVPAPARHTLGRCVRCPSMWPTFIDYNPLPLVQEDDNFGQPKNFAVIQRDYSVRAASGQSVDPWNLGFRFRFSPSRESGFDNRALVLADGTDISKQTALSAGIAYYHRKGHWKEPPNLLNPYWRATLVPLTVDEDGEDDVPDTLGDVGTGWAGETFEALRGQGYEGGP
>NZ_CP022098.1|WP_095983878.1|749504_750494_+|pilus-assembly-protein
MRSLSRRRASRGQSLVELVLGLLVFVTVLMFGIHFAEIGYLSVKVTEASHSALLDTTGHRLHSWPSNNNPSDRAAEIAAAEATERYRDFDSRTSTAHGDGLAQVFTRVSGLNVTCRTGAGPSFGPSLLTSVAYEDAGGLSCQSEALVEPVGAYTLPRKFMEDANGFFSQPHLLRPDPFRVCGMGRARGGVCTGRLTMALDDWGLSGDSESGICPFIPDVPAPCPTNLPFYAMAASVFTLNGLGQGIAGSRMAMGIVKRMPMPFFYGGENMFWMSSAGEPLFLQPTGFSMAEGWPLWPTTPGAAPIGVPGLAYSFAYLKRDGCFLGKDCP
>NZ_CP022098.1|WP_095983879.1|750493_751258_+|hypothetical-protein
MLLVLTWLLAASPTSPSPAPERATAGAPSAPSGTPVNGLPSAPSGTPVPLRWDVPGLLAWVDTDGPIAANGIPVLIQLARSSRSVDDLASHFVRFFEKAGLYVAPLEKQAAISREPQLTALDPKQMLSYTVILQANPDKTTSVILGTANVGAWKPQNQSQSLGWAPLMPGARNLLRTEAEGQSSAAYDVDSTPDKVQAFYREQLEKAGYKATGQSGEYRRGTEWLRVRARSDDKGLMVWLVRQLGGVDPAAPAP
>NZ_CP022098.1|WP_095983880.1|751295_751586_-|hypothetical-protein
MKHSPLLALALCCLLPAAALAKDPSPTRRDKEPKPVMNTQQAQALNKCMSKCQDPMKSCVEDCKGNQDCSMSCGEKFTTCITKTCGDLLPEAKPLD
>NZ_CP022098.1|WP_095983881.1|751710_754611_+|isoleucine--tRNA-ligase
MNDAGAPPQDPKDTVNLPKTDFPMKGNLAQLEPRMLGWWADHGIWGKILARRVGHEPFVIADGPPYANGHLHAGHALNKVLKDIVVKYRNLSGRQCDYIPGWDTHGLPIEQAVEKRLKDKKIDKRTLDREAFLSQCREYALEFIDIQRTEFKRLGVLGDWDNPYRTLDFSYEAQEIRELATFARRGMLYRRKKPVYFCLTDQTALAEAEVEYEQHSSPSVYVAFPAGPEVAERVPVLAGREVSFVIWTTTPWTLPANLAIAVNAEYEYVFYALGERVICVAKDLLSRVLAEVKADELEVKTVKVKGSEVSATALVEPERILAYARGDELEGCTYRHVFHPREGKILLGEHVTLEAGTGLVHTAPGHGQEDYEVGLKYGLDIYNPIRHDGRFDDSVGEWLAGKKVFEANPIVIDVLADKGVLLNGKTDKVEHSYPHCWRCHNPVILSATYQWFIPLDKPLHGGEGKTYRQQVLDEVDRVQWVPSWGQSRIRGMLETRPDWCISRQRSWGVPIPIAYCEGCDEALISPELMENVAAAVEKQGVGVWYRTPVEHFLPEGQRACGRCGKTGFRRETDILDVWFDSACMFSAVLDRRQRVPADLFLEGSDQHRGWFHSSILVSVGTRDVSPYKACLTHGFVVDGKGEKMSKSVGNTVAPEKIIQQYGAEVLRLWVASSDYRNDVRLSDQILKGLSEGYRKIRNTIRYTLSNLYDFEPERDAVAAERLQPLDTWARGRLAEVVARVKKAYEAYEFHLVYATVVDFCAGDLSAVYFDILKDRLYTSKATGEARRGAQTVLYEVATVLLRVLAPIMSFTAEEAWQYLPGKKTESVFLTDFPEPAVKPDAVLAERYAKLFAVRGAVQGLLEAARREKMIGSSLEARVVLSASGKAREFLQAHAAELPGLLIVSQVELADEAGEKAQVLAVAQALGEDVKAEVLPARGAKCPRCWTYSEQVAAGASVCGKCQEALS
>NZ_CP022098.1|WP_157758210.1|754607_755069_+|DUF4430-domain-containing-protein
MSGVLNPSRRSLLGCLALVVLGFASVPTWADEPAKKAPEGKSAPATVSVVFDYGNGKEKALTGIEWRQGMTAWEATQAAARRSPPIELKHSGSGAMVYVTGIDGVKNQGGGRDKRNWQLWVNGTYADAGVGAKVLQAGDKVLWKFAPPPPPGS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_7

1890278-1890380

Orphan

Consensus_repeat	Method
CGGGATGGTGTCAAAGGACTCGAAACGCGGGACCCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022098_7

>merge|NZ_CP022098|7|1890278-1890380|CRISPRCasFinder
CGGGATGGTGTCAAAGGACTCGAAACGCGGGACCCAGCCGGGATGGTGTCCGCCGGGATGGTGTCGCCGGGATGGTGTCAAAGGACTCGAAACGCGGGACCCA

>NZ_CP022098|7|7|1890278-1890380|CRISPRCasFinder
CGGGATGGTGTCAAAGGACTCGAAACGCGGGACCCA	GCCGGGATGGTGTCCGCCGGGATGGTGTCGC
CGGGATGGTGTCAAAGGACTCGAAACGCGGGACCCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_157758312.1\|1893461_1894757_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095984668.1\|1870860_1880475_+\|non-ribosomal-peptide-synthetase	unknown	unknown	gnl\|CDD\|237054
NZ_CP022098.1\|WP_095984670.1\|1882255_1882978_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_157758313.1\|1896591_1898667_+\|DNRLRE-domain-containing-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_157758311.1\|1891670_1892090_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095984677.1\|1900714_1902847_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377853
NZ_CP022098.1\|WP_095991866.1\|1867900_1868287_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647
NZ_CP022098.1\|WP_095991867.1\|1883071_1884271_-\|ISAzo13-family-transposase	unknown	unknown	gnl\|CDD\|369439
NZ_CP022098.1\|WP_157758310.1\|1887924_1889565_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095991869.1\|1904807_1905209_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647
NZ_CP022098.1\|WP_095984667.1\|1869610_1871335_+\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|380456
NZ_CP022098.1\|WP_095984679.1\|1906692_1907838_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095984666.1\|1868411_1869152_+\|glucose-1-dehydrogenase	unknown	unknown	gnl\|CDD\|235816
NZ_CP022098.1\|WP_157758309.1\|1884607_1886668_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239807
NZ_CP022098.1\|WP_095984676.1\|1900180_1900573_+\|transcriptional-regulator	unknown	unknown	unknown
NZ_CP022098.1\|WP_095984678.1\|1902946_1903426_-\|response-regulator	unknown	unknown	gnl\|CDD\|381106
NZ_CP022098.1\|WP_095984671.1\|1889572_1890190_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_157758314.1\|1899170_1900184_+\|type-II-toxin-antitoxin-system-HipA-family-toxin	unknown	unknown	gnl\|CDD\|377920
NZ_CP022098.1\|WP_095984672.1\|1891135_1891663_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095984669.1\|1880471_1882250_+\|acyl--CoA-ligase	unknown	unknown	gnl\|CDD\|223395

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_157758309.1\|1884607_1886668_+\|hypothetical-protein	gnl\|CDD\|239807	cd04280, ZnMc_astacin_like, Zinc-dependent metalloprotease, astacin_like subfamily or peptidase family M12A, a group of zinc-dependent proteolytic enzymes with a HExxH zinc-binding site/active site. Members of this family may have an amino terminal propeptide, which is cleaved to yield the active protease domain, which is consequently always found at the N-terminus in multi-domain architectures. This family includes: astacin, a digestive enzyme from Crayfish; meprin, a multiple domain membrane component that is constructed from a homologous alpha and beta chain, proteins involved in (bone) morphogenesis, tolloid from drosophila, and the sea urchin SPAN protein, which may also play a role in development.	6.75077e-75
NZ_CP022098.1\|WP_095984668.1\|1870860_1880475_+\|non-ribosomal-peptide-synthetase	gnl\|CDD\|237054	PRK12316, PRK12316, peptide synthase; Provisional.	0
NZ_CP022098.1\|WP_095984669.1\|1880471_1882250_+\|acyl--CoA-ligase	gnl\|CDD\|223395	COG0318, CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	2.94233e-64
NZ_CP022098.1\|WP_095984678.1\|1902946_1903426_-\|response-regulator	gnl\|CDD\|381106	cd17554, REC_TrrA-like, phosphoacceptor receiver (REC) domain of Thermotoga maritima response regulator TrrA and similar domains. Thermotoga maritima contains a two-component signal transduction system (TCS) composed of the ThkA sensory histidine kinase (HK) and its cognate response regulator (RR) TrrA; the specific function of the system is unknown. TCSs couple environmental stimuli to adaptive responses. TrrA is a stand-alone RR containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.69336e-16
NZ_CP022098.1\|WP_095984677.1\|1900714_1902847_-\|hypothetical-protein	gnl\|CDD\|377853	pfam07504, FTP, Fungalysin/Thermolysin Propeptide Motif. This motif is found in both the bacterial M4 peptidase propeptide and the fungal M36 propeptide. Its exact function is not clear, but it is likely to either inhibit the peptidase, so as to prevent its premature activation, or has a chaperone activity. Both of these roles have been ascribed to the M4 and M36 propeptides.	1.71179e-07
NZ_CP022098.1\|WP_095984666.1\|1868411_1869152_+\|glucose-1-dehydrogenase	gnl\|CDD\|235816	PRK06500, PRK06500, SDR family oxidoreductase.	8.54634e-81
NZ_CP022098.1\|WP_095991867.1\|1883071_1884271_-\|ISAzo13-family-transposase	gnl\|CDD\|369439	pfam07592, DDE_Tnp_ISAZ013, Rhodopirellula transposase DDE domain. These transposases are found in the planctomycete Rhodopirellula baltica, the cyanobacterium Nostoc, and the Gram-positive bacterium Streptomyces.	0
NZ_CP022098.1\|WP_157758314.1\|1899170_1900184_+\|type-II-toxin-antitoxin-system-HipA-family-toxin	gnl\|CDD\|377920	pfam07804, HipA_C, HipA-like C-terminal domain. The members of this family are similar to a region close to the C-terminus of the HipA protein expressed by various bacterial species. This protein is known to be involved in high-frequency persistence to the lethal effects of inhibition of either DNA or peptidoglycan synthesis. When expressed alone, it is toxic to bacterial cells, but it is usually tightly associated with HipB, and the HipA-HipB complex may be involved in autoregulation of the hip operon. The hip proteins may be involved in cell division control and may interact with cell division genes or their products.	4.02439e-07
NZ_CP022098.1\|WP_095991866.1\|1867900_1868287_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	5.83406e-37
NZ_CP022098.1\|WP_095984667.1\|1869610_1871335_+\|AMP-binding-protein	gnl\|CDD\|380456	cd19533, starter-C_NRPS, Starter Condensation domains, found in the first module of nonribosomal peptide synthetases (NRPSs). Condensation (C) domains of nonribosomal peptide synthetases (NRPSs) catalyze peptide bond formation within (usually) large multi-modular enzymatic complexes. While standard C-domains catalyze peptide bond formation between two amino acids, an initial, ('starter') C-domain may instead acylate an amino acid with a fatty acid. NRPS can use a large variety of acyl monomers (approximately 500 different possible monomer substrates as opposed to the 20 standard amino acids in ribosomal protein synthesis) to construct bioactive secondary metabolites of 2 to 18 units long (with various activities such as antibiotic, antifungal, antitumor and immunosuppression). There are various subtypes of C-domains such as the LCL-type which catalyzes peptide bond formation between two L-amino acids, the DCL-type which links an L-amino acid to the D-amino acid at the end of a growing peptide, starter C-domains which acylate the first amino acid with a beta-hydroxy carboxylic acid, and heterocyclization (Cyc) domains which catalyze both peptide bond formation and cyclization of Cys, Ser, or Thr residues. Typically, an NRPS module consists of an adenylation domain, a peptidyl carrier protein (PCP) domain (also known as thiolation (T) domain) and a C-domain. NRPS modules may also include specialized domains such as the terminal-module thioesterase (Te) domain that releases the product via hydrolysis or macrocyclization and any of various C-domain family members such as the epimerization (E) domain, the ester-bond forming C-domain, dual E/C (epimerization and condensation) domains, and the X-domain. C-domains typically have a conserved HHxxxD motif at the active site; mutations in this motif can abolish or diminish condensation activity.	4.31993e-94
NZ_CP022098.1\|WP_095991869.1\|1904807_1905209_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	4.29581e-36

>NZ_CP022098.1|WP_095984671.1|1889572_1890190_+|hypothetical-protein
MTPNIHYENREIEGEHLELTDKTAIYWLGPNVTLRGCTLVTNVSARWLHLVSGTLIDCTIHAKSELKTLPWAAMKLKGCRFKGRFGGNDFGLREDLDERQKLGGIEDCDFSEARLNGCRFRNCDMKTIRLPRWPCFTFLDPLMHVAELRRHAWPGLVGRATVEAVCESPVGTVAVTWHAPTVAEKMDTTVEELRAALETAPGIFM
>NZ_CP022098.1|WP_157758310.1|1887924_1889565_+|hypothetical-protein
MSKKQPNPTVGKGGGTQLGVRRGPPRWAPAGALWLIVLIFHAACASQGPASSRGTGGGRAGDEAAESEARAAPRELQPVLVVYAAEVEARGSTRVVAVTREEYQRAVAQLLQHHQVHGTPQEAAQGLLQAMPEEELLAEVYRDRVLTLVPLIDKGSLVPEAEAALKAKYLRWCQPRGGGDCLGLFTDGPYLRTDDRRTLALALAFGGVLDETRAALGRELSPQALLSSLVWAAGLYLALWLLPEPSTKAAAAALSVVLLAWLGVDAMWGLMDGWARMAHAAHEATTFEELRDAGEAFGKRIGMDAARALILAVATLTGRTLGEVATHLRSLPRFNQVQAQWAAQGMEGSVAVAMEEAAAVEVVVEQSRALVVLTSPQAPVAINVLARSGGSGAARGHGGTVAIQHRGGNKQVILGNGERWHLPRGQSYNDIPAEDRLGDELQAAVREEAARWSQAELSVEELEAIKKMRAAGKEYRANLLERQARGRWIERQVANRFPHLSWNSRGVDVTGPGGQSYHYEILSGTESNFALHGRRMASTFFRMIFF
>NZ_CP022098.1|WP_157758309.1|1884607_1886668_+|hypothetical-protein
MSIKTLKAVSSATCMTMAIRLLTACGHEAGQPELRPAWSDPESAWVPAHSPVLEGYVWNGARERFEAVRYADVDGMAVLEGDILLGSVEQVKAHTREVQAHGGLQPQGVRAQGVAISGLRYRWPDATVPYTIDPSLPSQFRVTDAIAHWQSKTPLRFVLRTASNAALYPNYVTFRPNNGCSSSVGMRGGQQFINLEAACSTGNTIHEIGHAIGLWHEQNREDRDSNVRILWENIQADYAYNFDQHIGDGDDVFSYDFGSIMHYGAYAFSSNGLPTIETLGGQSIGQRDGLSFADVNATIKLYSRQILANESIPSFQTWAARTRTVVTGDFNGDGRTDIAAVGADGWQALPVALSNGNGSFRVVNESIPSFQTWAAQTRMVVTGDFNGDGRTDIAAVGADGWLALPVALSNGNGSFRVVNESIPSFQTWAAQTRTVVTGDFNGDGRTDIAAVGADGWQALPVALSNGNGSFRVVNESIPSFQTWAAQTRTVVTGDFNGDGRTDIAAVGADGWQALPVALSNGNGSFRVVNESIPSFQTWAAQTRTVVTGDFNGDGRTDIAAVGADGWQALPVALSNGNGSFRVVNESIPSFQTWAAQTRTVVTGDFNGDGRTDIAAVGADGWLALPVALSNGNGSFRVANEFIPYFQTWAAQTRTVVTGDFNGDGQTDIAAVGGEGWGTLPVALLDY
>NZ_CP022098.1|WP_095991867.1|1883071_1884271_-|ISAzo13-family-transposase
MEAAIRAKYLALEGVLNERARRLWAATESLTIGYGGDAVVASATGLARATIRAGREELKKGEAVTERQRRPGGGRKALALVQGGWVEALERMVAPTTRGDPMSPLRWTCKSTRNLAAELRHEGFVVSHMSVGKKLHELGYSLHALRKNQEGTSHPDRNAQFEHISAMVEDFQARNQPVISVDTKKKELVGSFRNVGREWQPTGRPEEVNVHDFPEDAVGKAIPYGVFDMTRNEAWVSVGRDHDTPAFAVASIRQWWKTMGLPAYPSATELLITADAGGSNGYRTRAWKKELQELADDTGLNIHVCHFPPGTSKWNKIEHRLFCHITQNWRGKPLTSFETVVNLIGRTRTTRGLRVKTRLDKKQYPTGVEITKTEMKRLALRKDDFHGDWNYLLEPRRTE
>NZ_CP022098.1|WP_095984670.1|1882255_1882978_+|hypothetical-protein
MKQVPDHEDEVLDLERHQDPGRNRITPVLQLPPEVALTVVTALAGLVRHAHRREHESPTPPRALKEAQSFEEGDVFMLAPPFEGYFADRYLMDFYDTRERGICSRMHLHTGLRFVRMMTGPDTTIRVSSLSPLTVRSRPDWTTPLHAFVDRLPDTPEGVHRERYNVVVPPNCWVDMQIPRGVSHQFNAVGPHAVIDSVHPEESIETLREGMSGYRMMAQTIFLAEHRSSAATCEDTGDGG
>NZ_CP022098.1|WP_095984669.1|1880471_1882250_+|acyl--CoA-ligase
MIDYLPAGARVVVRLPNGPGLAKALLGCFDRELVAVPLHPRSTDTAVRGIVDRVAASAVLDEHGLHDTGHPAEHPDAEGLAFLMFTSGSTGPQKGVMLSRKAVLGNAAKTAALHGLTPDRPHGTCLPLYHCNALVMSLLGTHFTGTPLVLHNGADPAGYFAALRAAGARTASIVPALLADLLDVSPEWPEDLEYLITAAAPLTSDLARRFHDRYGPRLRQGYGLTEAMNFSFTTPLLDEAAFTRQYLDQHPPVGVALPETELRLVDGEVWVRTPDMMRGYWQDPAATAAALTEDGWLRTGDLGELREGLLVLRGRAGERIDRGGEKYHPLDVERTWREAGLGGRFAAVAVAEPTLGHEIGLVATDQPVEAVRAVCENSPLRPASVQFGGFQATSTGKPQRKAMGRSLVALRYAPARYERLLRYASATAHDLLRSGVDDAGLRALAEHVDEPAREGEEAVFEALEFMRAHWHRRADPELAEAKARWREQLSTEWPLAGYAELAERLREAHPGAVVSSHLPTITTLDGCPWALGPLLSFLDYPTQEPGDRWHGLAGLREAGFAVVGCALLRAGRHDLGGVLWAHTPTSGNRGNE
>NZ_CP022098.1|WP_095984668.1|1870860_1880475_+|non-ribosomal-peptide-synthetase
MAVGRGHPGHAPGRHPAHHGRRARAPDRPGHRGRTGGASQHGALGLRRAGPPTAGGRRGALPEDRAAADLPRAGRAGHRPGRPARRGGAGPGRNVALLLPRSVDLVVAVLAVLKSGAAYVPLHAEDPPPRRASVLADSGARLLLTDQADATAPGLRVLTVNGTGPDAACPEVGGGDLACVMFTSGSTGTPKGVAVTHANLVDLAADRWWTEGGAERVLLHSAQAFDAINLELWIPLLTGGEIVLAPPGRLDPGELARTITTAGVTGMWLTAGLFNAIATQDPRCLAGLRQVWTGGDVVSPAAVRAVREALPELTVVNGYGPTETTVFATRYPAGPITDVVPIGRPLDGTRVLLLDGAMRPVPLGTTGEVYLGGAGVALGYLNRPGATAERFLPDPSGPPGARVYRTGDLARWNAAGQLEFAGRADGQVKLRGFRVELGEVDAALLAQPGVRQAATVMREGRLVSYVVGEVPDGLLERLGERLPPFLVPSAVVGLAALPLTRNGKLDRAALPDPSAPAPEPVRATGTAVERTLAKLFAQVLGRAEVPVDGDFFKLGGDSIRAIQLAAAAQRAGLAVSTSDVFRAPTVTALAKGLALPAARGRSLALGDPDDPTVPLTPVMHWLRGRGAPDNRFVQSMTVRTPAGCTAEQVRAVVQALVDHHGMLRLALSEVQGVWALRVLEHVTVKLDRPINLALGHVLHVTWREDRLKLTAHHLCVDGVSWRILLDDLHTAWAAVRDGRAPTLPATGTPFPQWARALLQHAHHPDLLADLRRWLAPVADPPVGDRALDPSLDTEDTRQWLSISLPADFLPKAAAAFDCSVYELLLTAFALATGPVRVELEGHGREEFADGLDLSRTVGWFTTLYPVQLAAGCSWPTDPVDLDGAVARVRETLNGLARTGFGHGLLRHLNPQTAPLLAGVPAPRYAFNYLGHFDVNGDGDWAVLPEDTVVGATSGGPLALAHAVELDAVLANHPDGPRLVANWSWPGRLLPREEISALAERWFEVLTALGTRARARATGALPLPPLAQGLLFHSLYDHDGADPYLVQFVFELEGALDAAGLRTALHRLLLRHPQLSAGVRQSPAGRPVQVIDPEFSVPWHDLPAHEDLEAFLAQDRQRRFDLARPPLFRAALQRRAADRHVFVLTTHHLLLDGWSMPIVVKELFGLYAGQPLPPAPAYRDFLDWLATRDPHAAEEAWRDILSTVDGPTLVGGPGRRGSASARLRCEADLPAGIAEVARRHGVTPNVVVQLAWAVLVGALTGRQDVVFGATVSGRPPELPGAEGMVGLLINTIPVRVGLAPARTVADALAALREQQLAVLDHQHVDLTRLQALAGQSELFDTVVVFENYPLEEEALPGLVLRSARGLDGTHYPLTLVVMPGEHGRLRLDHSADVLDAEGAHRLLARLASILAQFADRPDASLGGLDLLLPDEHEPVPTPETARRCTLPELFEAQVRARPDAVAVTFEGEHLTYRELNARANRLAHHLVARGAGPERLVALVLPRSLDLVVAVLAVLKSGAGYVPMDPDQPEERLRQVLAAVNPVLVLDQVDPSKEHPEHDLGPRADPDGVAYVIHTSGSTGVPKGVVVSHQNVVRLLDTTDPWFGFGPGDVHTLFHSYAFDVSVFELWSMLAKGGRLVVVPKHVTRSPQEFLALLARERVTVLSQTPSAFYQLPPADLALRVVVFAGEALALSRIRAWRRPGGPKLVNMYGITETTVHSSYIELDDPEETASVVGVALPDLRLHLLDHALRPVPPGCPGEIYVAGPGVTRGYLNRPELTAARFVPNPFGAPGDRMYRSGDLARRRQDGGLEYLGRADQQVKIRGFRIEPGEVERVLERHPSVVQAVVLPDEDRLVCYAVLTGDLDAAGLREHARRVLPEHMVPAFVVPVPKIPLTGNGKLDRRALPRPQSTLPVSRPPRTPMEKLLCALYAEVLDVPEVGAEDSFFDLGGHSLLATRLINRVRAETGAVLGIRTLFDAPVVADLARCLPEVPTAPDTAFTPGARPAHIPLSAAQRRLWFFSQFAGPNSVYNMAFATRLRGDLHEDSLRAALHDVLERHESLRTKVVEGGGEPGQRICSADELPVHSLAVPESALADRLAEAAGHVFDLTAELPVRALLCRTGPREHVLLLVLHHIAADGWSLSPLARDLSTAYRARLDGNSPRWTNRPVQYADYALQQRNTHPAHWVEVLRGIPDVLPLPTDHPRPAVSAHRGETVGFRLDAALHGRITELARAHRASVFMVLHAAIACLLHRLGAGADIPIGTPVAGRHDAALHDTVGCFINTVVLRTDLSGAPTFAELLARVRAVDLDAFAHQDVPFEQVVEALNPPRSLSRHPLFQVMLAIQDTPAAEFSLPGVRAEPVAVHGGASRLDLLWSLRQESDGIDGLLEYNTELFTPATARLLLARLDLLLRAAVADPDRPVTDLPVLVPGERERLLTRWNDTARTVPDTSVHSLFAERARAHPHALAVDDLTYGQLSERVEQLAEQFRALGAGPGSLIALVLHRTADLPAAMLAADLVGAAHLPLEPGLPPERLTALLADARPALVVDNENGLRVTARPGTPVPEDTAYVRYTSGSTGRPKGVVVPRSARLNLLHAMRERLDLTPADRVLASAPVGFDISELELLAPLMTGAAQVLADRDTVREPDELLALLERRQVTVVQATPSLWHALAARRPECLRRVRALIGGEAVPGGLAEELRGRVSSLLACYGPTETTVWSTLHPVTGATGATVPIGRPLWNTRCHVLDERLNLVPPGVLGELYLAGDGVATGYLRQPGLTASRFLPDPYGPPGSRMYRTGDLVSRSADGVLRFHGRTDDQVKVRGHRVELGEVEAVLAQHADVHAAAVTVHRKGVLIGYLVPAVAEPDLPAISAHLARHLPDHMVPARLVAVPEFPLSANGKVRRDQLPEPDWSVAAEVTATPEEQLLCGLFADVLDLPSVRPGDNFFELGGHSLVAARLSARVRAVFGVALGVRDVFTAPTPAALAARLAGAAETGPLVPLRTGGSAAPLCCVPALSGLSGVYAGLLPHLDGEHPVYGLHTDDLPDSIEELAEHHVTALRAAHPDGPYHLLGWSFGGLVAHAMAVRLRELGAPVGLLVVVDSVAGAVAEAGPVEERITRLLGRDSAPLAAVARNNERLLRAYRPPVYPGDVVYFNAAGGSNHERWRSHVGGRLTVHQLAAAHHEVFQPEHVAEAGALLRDELRRNR
>NZ_CP022098.1|WP_095984667.1|1869610_1871335_+|AMP-binding-protein
MGSHVVDQSAELELSDAQTGVWLAERSGHSRPGSYQWAEYLDLCGTVRTDLLTAALTRAAAECEAVRVVFEATADSLPRQRVLDSAEPRVTTVDFREAPDPVASARAWMAERLAAAGEELFLGAVLRLAEERQWLFLRVHHIALDGAGMALLVRRVAEIYECLREGLAVPGPGWAALAEVPSAEQAYRDSAALAEDREWWLARLADRPEPVVVGSRAAPAAETSVRWTRVLAEGEFARLRQGAERLGTRWSRVVAAATAVHVQAVTGQSDLLLSLPVSGRAAEVAVPAMTANVVPLRVRVNLAGTVGGLLQEVSAQLHAIRSRQRYRGERLRRELGLPEDGRKFFGPVLNIQRFDHVLRFGSATVTVHNLQAPPSEDLSVVAYDRADGRLRLDFDANPTTCSPKRLRELGERFEHVLWQLVEATPDTPLVDIQPTTAAERAHLIDLGTGAAQAARASTVPSAFAARVRQQPEAAAVHCPKTGRRLTYRELDERATALAARLAGAGPGPAATSRCCCLARWTWWSPCSPCSSPARPTCPCTPRTRRPGARPCSPTPGPGCCSPTRRTRRPPVCAC
>NZ_CP022098.1|WP_095984666.1|1868411_1869152_+|glucose-1-dehydrogenase
MTRFKDKVVVVTGGSDGIGLATAKAFAAQGANVYVTGRRQERLDEAVNEIGGATVGIQGDVSNLSDLERLYERVKRDHGRVDVVFANAGISETVTFGALDEEHFERVFGANVKGVVFSVQKALPLMTSGGTVILAGSASGSKGLPGLSVYNATKAAIRSFARTWTTDLKSRGIRVNVVSPGVIETPAIQTYLHNNAGMEDVLKQMTPLGRLGQAEDVANAVLFLASNESSFVAGVELFVDGGVMAV
>NZ_CP022098.1|WP_095991866.1|1867900_1868287_-|helix-turn-helix-transcriptional-regulator
MLSDTEDDPIYRADCPSRTILDQIGDKWSMMVLAVLVRTPRRFNAIKRRLEGITQRVLTQTLRKLERNGMVRRRVIGGSPPGVEYSLTPLGRSLQEPFAALYDWTLAHIDTIQKHQEAYDRERPPGAP
>NZ_CP022098.1|WP_095984672.1|1891135_1891663_-|hypothetical-protein
MGHQINFFLMPEDTRLLEKRLREECPVVFLDGESRDSAPVQLPDLEVAEFGKTRLRVILVQPEDLKSVILRYIPQQGHWSVDSDRSPVIELDRCYYDGEILRRGRLYYQRQFAEHGAWVEKPAAFQAWAKRVFSVTRKTLQKLPDRPYHVGPHALAEQRQGHVKLMASTNKPLLP
>NZ_CP022098.1|WP_157758311.1|1891670_1892090_-|hypothetical-protein
MKELLAVSLLLWCGLSLAAPRVPKAVPNKATVQSVKTPPNPNGRKGGTEHQAKVKEVAQEVEARGLQPKTEHMVETPGGTKSKRFVDVVGTDKKTEEVKEMHQVGLQTKKGQPVTRERQALDDIQKAEGKRPEFHPYNK
>NZ_CP022098.1|WP_157758312.1|1893461_1894757_-|hypothetical-protein
MASAILVTSTAISSVAHAEQLNITFQGTIDPMFGIEGNYHYGVMTANCGYKHISEQCNGTVASGPSYGAWFDGPINPYKFGSETYFQIPHSQNYRIKVTGNNWGARHLWQMEPNNTVHGATITPADSDLNQSHYQMRNWIFSPYVQYPNIYGLTHHEWYSSVSFVNGIPFLAPGATTVWGLGWISSADGGNTWAMNPINYNAPSNSNRMVLIPEPWNSSLPNFYGFSHPSNIVKEGIYYYAFMTNVGQKSNGKQTLGVSLIRTSNLASSSGWQYWNGSGWTTVNQGTYQGNSGPQQPYIFWESTNACSHLYAHNVRKHASSGKWIVLGAAYCTDVDANGNILGKAVYSWINSLANPALLDKTAAGQSRSPQVIPAVGNYIPFNAYYSFFDVSGSQNVGDNFEVVNDTPLFTAINPAKNTILHQFLNISYTP
>NZ_CP022098.1|WP_157758313.1|1896591_1898667_+|DNRLRE-domain-containing-protein
MFAILHSAMGTPGAIARGGHGGPNVSRRHGRGWWGGVLSVLWLAGCGDMGSPRELASAGVGVASSPVLPERCMPRTDSYVNASSPFEDSYVSQREPTVNFGTSPVLMVDGSPRLESYLKFSPFSEGLAIRAARLEFTSVDGTSDGPRLYRAGDDWTEGELTWNNRPPVLGGVLGDLGAIHPSTRVSYDVTGVVTQEQPYSFVLLSDSSDGVDFYSNESVQAERLPMLVVTTESPPFCSYRGSGTGGLSAWVRQLGGAGAESVSVVAPHPQGGFVAAGLFGDAVFAEGEGLALARYGADGTFQWSSVVATNDVLVTDITVTSLGNLLVVGRYHNAPDLGTGPFPSAPEEEAWMAGFFIAKFSPVGRLVWAHGFVARDATGMLQRVAPQAVATDAHGSLLVTGGFSGQMDLGTGPIDSGSTGEPGFAMNTGGFVAKFSWEGQPLWSRALRTHLAGQYVQGWTVAADAEDNVLLGGSASALTDLGDGPLGEEGWLGDPVPFLAKYTPSGDLSWKRVFSGGAGEVRVIQPQGADRIAFGANIAGFFTFAGHSYEGEFLETLSASGFLGVMTATGSDAWLRAVGEPVSLGELAVGNDGSLVLSGVGLEAFDVGGGALGFAWGSPFVPTNRPFVARYTAQGEHLWSRSFDQGRSLDMALLSDGGVLLGISLRWNFQLDGRTFTPVGGGDLLYLMLNP
>NZ_CP022098.1|WP_157758314.1|1899170_1900184_+|type-II-toxin-antitoxin-system-HipA-family-toxin
MIRWIADPPPLVAVSLNLPVKFHPKVWHHWPAFLDDLQPMGSARHWWLRRLSLADEGASDFDILRSGTIAPVGNLRIEESVPTKKELPKRFPRQAVIDREHAFIEYAANAGAQVGGATGAGGDSPKLLLRCDAADQVWIDVWQDDPACPDRHYLVKFARSRSERDRNILRSEYVYYKALAELGVETIAQDGLALHEGPSGPSLWLPRFDVARRGGREIRYGLESLYHCRNIAVLKTDSAVRLAPIFDFAPMRMDLDGITRTTTWEGYEAGGDVDWDGLLRSFGPDEASLREGLRDLASRLRHLPELLAGLGLPDETLNFAGLDLRGTEKRLRAWGLL
>NZ_CP022098.1|WP_095984676.1|1900180_1900573_+|transcriptional-regulator
MKRADVARLTALERKALLEELAAMVVTGEFGLGDAARILRGTMLGMDRKTFAQAVRLSTSVVATLEDDPNANPTLETLNKVFAPFGGKVVLSFPRIEEPPPPDDAERRRREMLRAALAKNRRQRRRSTES
>NZ_CP022098.1|WP_095984677.1|1900714_1902847_-|hypothetical-protein
MQRPGLQILALSLTLGIAEAAPAQAPALAPAKSVTTDNLTVYSGARATSPEQALRDNAERFGLPASLENLVLVQVKESLLGKHYHYQQMLLDLPVDGAEIVVSIGKDGQLLQIHNTSRHVGEDMEEAAVNQLHLKAQLSSESALDRAWTNMRVQNPLVDLPKSEQVWLPVKDGFQLAYKVSISAQMPTGGFVQYINAQDGSLIDSYSTSMPRNGKFEERTLAARQRTLGSPLDRKAETAAIERQTRLAQPVTSLVPSGIDGSGFVFDPDPRTTLNNDNLTDSSAASAFESAYFNKPLRDISLSGGVYSLTGPYVNIKNIEAPNTAPSTTTNGAWTAKRGSDAFDDTNVYFQLDQNQRYIQSLGFTNIINRPFDVDTNGVNGDDNSHYSYGGSTDYLAFGHGCVNDSEDADVILHEYGHGIQRNINTSWSGGDTGAMGEGFGDYWAASYSYSTPNGPTYHPEWVFSWDGHSNCWSGRALNRTDARYNSIRTYGAHQSITEGGVTFVSDELWSAPLFQALTSLMANGKSRADVDKIILQAHFGLGSGVKMPAMATAIVNAAHNLFPNDVTYENTFKAKFEAQNIISSVPPGPTINETESNDTQATANELSTTNTTVNAAIASRSDVDFFKVTLPAGKTLTASMTPNSTSDYDLELYNSAGTKLTSSTAGTGAVDSVTRSNSGTTSADFYVKVIYYSGGTGSTNGKYSLVATW
>NZ_CP022098.1|WP_095984678.1|1902946_1903426_-|response-regulator
MSMHPNPRRLLVIDDSEAIHTDFRRILTDEPLKSRGELDLMADALFGPEAAGSSEGKTVVEVDSAYQGEEGVERVREALAAGRPYALVFLDYRMPPGWNGAETLRHLRQVAPTLPVVLCSAYSDYSWAELQAEFGESRLLRQLRKPFNRQQVRELALGD
>NZ_CP022098.1|WP_095991869.1|1904807_1905209_-|helix-turn-helix-transcriptional-regulator
MLSDTEDDPIYRADCPSRTILDQIGDKWSMMVLAVLVRTPRRFNAIKRRLEGITQRVLTQTLRKLERNGMVRRRVIGGSPPGVEYAITPLGRSLQEPFAALYDWTLAHIDTIQKHQEAYDRERPPGAPPEKVS
>NZ_CP022098.1|WP_095984679.1|1906692_1907838_+|hypothetical-protein
MGSGAQLHVIGIYQAALGADGTRSVQVRVTRAGSSVLVLSAYTATTWNVKVEPGANVERIIVNGYHAQKVSAPAGVPVEIRSYEQTQNYVGPFAYEWPAYKSTQLVNAAEDLVERNLSSFRGCYEAASFEIGEPGTLRPENTVSTASDPVVPRGCEQLTTESAYCMTLNYNTPTVVGLDSGRTCAGVPSKLSSLYDVSSLAWNGNYLYGCIHDRGLARISLVDGSTDIAPIACQAVTSYRNGLLTLLDYDGTNTSVLNTPVQFDSFRNAARHVTSCTLNNRPHASRMAAGGDRGYFAWHSTDSIETFALNRTESPQTIKLEGYSGWIMGMDATEDGRLLILGNNPELLSFNSTTGVALGKKALPFRANGLICKTRSATVIP

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_9

2249796-2249863

Orphan

Consensus_repeat	Method
GGGCCTCGCGGGCATTGGCTTCGGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022098_9

>merge|NZ_CP022098|9|2249796-2249863|CRISPRCasFinder
GCGCCTCCCTCGCGCTGGACTCGGCGTCTTCCTTGCGTCGCTGGGCCTCCCGGGCACTGGCCTCGGCT

>NZ_CP022098|9|9|2249796-2249863|CRISPRCasFinder
GCGCCTCCCTCGCGCTGGACTCGGCG	TCTTCCTTGCGTCGCT
GGGCCTCCCGGGCACTGGCCTCGGCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_095991897.1\|2232923_2233532_-\|RDD-family-protein	unknown	unknown	gnl\|CDD\|377640
NZ_CP022098.1\|WP_095984905.1\|2233576_2234323_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225818
NZ_CP022098.1\|WP_157758352.1\|2234345_2235278_-\|TraB/GumN-family-protein	unknown	unknown	gnl\|CDD\|350614
NZ_CP022098.1\|WP_095984903.1\|2230162_2231653_+\|glutamate--cysteine-ligase	unknown	unknown	gnl\|CDD\|225081
NZ_CP022098.1\|WP_095984902.1\|2228728_2230144_+\|hydroxyacylglutathione-hydrolase	unknown	unknown	gnl\|CDD\|226906
NZ_CP022098.1\|WP_095984907.1\|2235426_2235759_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095984917.1\|2263138_2263636_+\|folate-biosynthesis-protein	unknown	unknown	gnl\|CDD\|223792
NZ_CP022098.1\|WP_095984915.1\|2261723_2261975_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095984909.1\|2241258_2246580_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|226415
NZ_CP022098.1\|WP_157758351.1\|2231749_2232844_+\|diguanylate-cyclase	unknown	unknown	gnl\|CDD\|143635
NZ_CP022098.1\|WP_095991898.1\|2256491_2258954_-\|ligase-associated-DNA-damage-response-DEXH-box-helicase	unknown	unknown	gnl\|CDD\|274994
NZ_CP022098.1\|WP_095984901.1\|2227430_2228522_-\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	unknown	unknown	gnl\|CDD\|223890
NZ_CP022098.1\|WP_095984908.1\|2235724_2241046_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|226415
NZ_CP022098.1\|WP_157758354.1\|2253063_2255802_-\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|369266
NZ_CP022098.1\|WP_095984913.1\|2255838_2256522_-\|ligase-associated-DNA-damage-response-endonuclease-PdeM	unknown	unknown	gnl\|CDD\|274996
NZ_CP022098.1\|WP_095991899.1\|2260604_2261624_-\|ligase-associated-DNA-damage-response-exonuclease	unknown	unknown	gnl\|CDD\|274995
NZ_CP022098.1\|WP_095984916.1\|2262121_2262889_-\|ROK-family-protein	unknown	unknown	gnl\|CDD\|224851
NZ_CP022098.1\|WP_095984918.1\|2263628_2264336_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212491
NZ_CP022098.1\|WP_095984914.1\|2259003_2260599_-\|ATP-dependent-DNA-ligase	unknown	unknown	gnl\|CDD\|236428
NZ_CP022098.1\|WP_157758353.1\|2252506_2252935_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095991897.1\|2232923_2233532_-\|RDD-family-protein	gnl\|CDD\|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	3.96204e-19
NZ_CP022098.1\|WP_095984905.1\|2233576_2234323_-\|response-regulator-transcription-factor	gnl\|CDD\|225818	COG3279, LytT, Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms].	3.96569e-51
NZ_CP022098.1\|WP_157758352.1\|2234345_2235278_-\|TraB/GumN-family-protein	gnl\|CDD\|350614	cd14789, Tiki, Tiki homology domain antagonizes Wnt function via cleavage of amino-terminal residues. Tiki is a membrane-associated metalloprotease that inhibits Wnt via the cleavage of its amino terminus, diminishing Wnt's binding to receptors. Wnt is essential in animal development and homeostasis. In xenopus, tiki is critical in head development. In human cells, TIKI inhibits Wnt-signaling, which is important in embryogenesis, homeostasis, and regeneration. Deregulation of WNT contributes to birth defects, cancer and various diseases. TIKI homology domains are part of the TraB family and are related to the Erythromycin esterase, GumN plant pathogens, RtxA toxins, and Campylobacter Jejuni heme-binding, Chan-like proteins. TraB/PrgY are identified in gut bacterium Enterococcus faecalis, but its function has not been well characterized. Plasmid-borne, TraB has been implicated in the regulation of pheromone sensitivity and specificity. Based on homology to TIKI activity, it has been proposed that TraB acts as a metalloprotease in the inactivation of mating pheromone. The TIKI/TraB family has 2 conserved GxxH motifs and conserved glutamate and arginine residues that may be catalytic.	2.83806e-81
NZ_CP022098.1\|WP_157758354.1\|2253063_2255802_-\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|369266	pfam07217, Het-C, Heterokaryon incompatibility protein Het-C. In filamentous fungi, het loci (for heterokaryon incompatibility) are believed to regulate self/nonself-recognition during vegetative growth. As filamentous fungi grow, hyphal fusion occurs within an individual colony to form a network. Hyphal fusion can occur also between different individuals to form a heterokaryon, in which genetically distinct nuclei occupy a common cytoplasm. However, heterokaryotic cells are viable only if the individuals involved have identical alleles at all het loci.	3.00276e-28
NZ_CP022098.1\|WP_095984902.1\|2228728_2230144_+\|hydroxyacylglutathione-hydrolase	gnl\|CDD\|226906	COG4529, COG4529, Uncharacterized protein conserved in bacteria [Function unknown].	7.60255e-93
NZ_CP022098.1\|WP_095984917.1\|2263138_2263636_+\|folate-biosynthesis-protein	gnl\|CDD\|223792	COG0720, COG0720, 6-pyruvoyl-tetrahydropterin synthase [Coenzyme metabolism].	2.65823e-07
NZ_CP022098.1\|WP_095984909.1\|2241258_2246580_-\|AAA-family-ATPase	gnl\|CDD\|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	9.2985e-137
NZ_CP022098.1\|WP_157758351.1\|2231749_2232844_+\|diguanylate-cyclase	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.91018e-38
NZ_CP022098.1\|WP_095991898.1\|2256491_2258954_-\|ligase-associated-DNA-damage-response-DEXH-box-helicase	gnl\|CDD\|274994	TIGR04121, ATP-dependent_helicase, DEXH box helicase, DNA ligase-associated. Members of this protein family are DEAD/DEAH box helicases found associated with a bacterial ATP-dependent DNA ligase, part of a four-gene system that occurs in about 12 % of prokaryotic reference genomes. The actual motif in this family is DE[VILW]H.	0
NZ_CP022098.1\|WP_095984901.1\|2227430_2228522_-\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	gnl\|CDD\|223890	COG0820, COG0820, Predicted Fe-S-cluster redox enzyme [General function prediction only].	5.74009e-128
NZ_CP022098.1\|WP_095984908.1\|2235724_2241046_-\|AAA-family-ATPase	gnl\|CDD\|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	2.71811e-136
NZ_CP022098.1\|WP_095984903.1\|2230162_2231653_+\|glutamate--cysteine-ligase	gnl\|CDD\|225081	COG2170, COG2170, Uncharacterized conserved protein [Function unknown].	4.35698e-08
NZ_CP022098.1\|WP_095984913.1\|2255838_2256522_-\|ligase-associated-DNA-damage-response-endonuclease-PdeM	gnl\|CDD\|274996	TIGR04123, hypothetical_protein, metallophosphoesterase, DNA ligase-associated. Members of this protein family are an uncharacterized putative metallophosphoesterase associated with a DNA ligase, a helicase, and a putative exonuclease. It may play a role in DNA repair. Its system is present in about 12 % of prokaryotic reference genomes.	1.83495e-83
NZ_CP022098.1\|WP_095984918.1\|2263628_2264336_+\|SDR-family-oxidoreductase	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	3.42238e-40
NZ_CP022098.1\|WP_095984916.1\|2262121_2262889_-\|ROK-family-protein	gnl\|CDD\|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	1.75615e-22
NZ_CP022098.1\|WP_095991899.1\|2260604_2261624_-\|ligase-associated-DNA-damage-response-exonuclease	gnl\|CDD\|274995	TIGR04122, hypothetical_protein, putative exonuclease, DNA ligase-associated. Members of this protein family frequently are found annotated as a putative exonuclease involved in mRNA processing. This protein is found, exclusively in bacteria, associated with three other proteins: an ATP-dependent DNA ligase, a helicase, and putative phosphoesterase.	0
NZ_CP022098.1\|WP_095984914.1\|2259003_2260599_-\|ATP-dependent-DNA-ligase	gnl\|CDD\|236428	PRK09247, PRK09247, ATP-dependent DNA ligase; Validated.	0

>NZ_CP022098.1|WP_095984909.1|2241258_2246580_-|AAA-family-ATPase
MLDIPGYRVLGTLRATGSNVLFHAVREADGVRVILKTPMAPSPGASENERYRREFAILQRLRDVRGVPRPYAHERIHERPVLLLERVQGETLSETTGQPMEVSRFLSLALSLVSTLAEVHGHDIIHKDIKPSNILLEPSGEARLLDFGLATLQRVEHLDAAPAHLIEGTLAYMSPEQTGRMNRAVDHRTDFYSLGVTFYELLTGRRPFQARDALEWFHAHLAQKPKPPHELNPQVPPPLSALVMKLLAKVAEERYQSAEGLNVDLERCREALGQGEHEVFPLGTQDTPQRFQLPQRLYGREEQVASLLEGFERVTRTGRPELLLLRGYSGIGKSSLVHELYKPVVRRRALFLHGKFDQFQRDIPYVTLAQTLRELLRQLLAGSEEELARWREQVNRAWDGQGQVLVDLVPQLEVLVGRQPALQELSSSEAQQRFFRVVRQFVSVFSTKEHPSVVFLDDLQWADPASLRLLEQMLSHPEGPPVLWLGAYRDNEVSPTHPLMAVVEKVREAGARLTDIRLEPLHVEHVEQLVDETLPGARQEVIAPLAGLVHEKTGGNPFFLRQLLVTLHQEGLLVRLPKEGWRWDAQGVRARGYSDNVVDFMVGKLRQLPPGTQHLLRLAACSGTVFSLQLLGTLSGLSAVEVVEQGLEPALREGLLGRVGTETYRFLHDRIQQAAHSLSSEAERQETHLRIGRLMLQNLSPEQVRESLFEVVSQLNAGMALMEDPTERHQLARLNAEAGGKAQAALALRPALTCFSTAFALIPGDPWETDHALAFQVRLAQARTELMSGSPSGAQRQLEELRPRTRTRADTVALYLLTQDIHFATGAFLEGMSCLRECLELLGMPVPRHPTWEEAVAAHEEAWALLGQRPIDSLLELPLMTDPDMKMAVVSLFKLFPGAYSSDPHLLIIILSRIVSLTLRHGVVDAAVPGYTWFGVITGSFFKRYREGFAFARLALGFVERYHLSARRGDVLLGMQFSSYWVQPLARAQELLLNSLRHALQVGDIAPATYCSVYLVNNRLAMGHSLDEVHQESLVRDEFLRQTGFVDPQEALLVSQRYVQQLRGHSLSFSTLSGEGFDERAYEARMTPERLGGTRCHYWLHKMQSRFMCGAYEEAREAADKTAGLLWSCFGTLNAREGHFYRALTLAACFEGATPERQREWLEAIGQHHQQLAEWAENCPENFRALERLVFAERARLLGRSEDATRAYEQAIRSARENGAIQYVGLASELAAKFWRTREAPIVAHAFAREARAAYQRWGARAKVHHLESQWPELTSTPSPQDSLSTSSTDSTHIDALTVVKAQQAISGEMEQERLVTALMRAAMENAGAQRGALLLPDGDALSVAALFQLSPEGTLVASDEAGHHELPWTLLAYVRRTSEHVLIADAAQPHAFSSDAYLARGEARSVLCLPLMRREQFSGALYLENDLATNAFSPARLALLGHLASQAAISIENARLYADVQRARTELRQANDELERRVEERTRELKQTQARLVDTAREVGMAEVASNVLHNVGNVLTSAVVNLEMMSRTAGALRVGRVRQTGTLLLEHREALADFLTKDPRGGQLPDYLVALGDEMMREQTRLMEDMATMNRHVEHIRAIVQVQQTYARHSLMTEECELSQLVDDALRIQLESLRRHGVTVHRELSRVPRVKVDKHKVLQILINLLSNAKHALDGVPEGQRNLWVRLAAEGNVARIQVADDGVGIAPELMDSLFAHGFTTRKDGHGFGLHSSALAAQLLKGRLTLESAGLGQGAVATLELPLTSEGSPRASS
>NZ_CP022098.1|WP_095984908.1|2235724_2241046_-|AAA-family-ATPase
MLDIPGYRVLGTLRATGSNVLFHAVREADGVSVILKTPMSPSPGASENERYRREFAILRRLQDVRGVASAYSCERIHERPVLLLERGRGEPLSESSGQPMEVSRFLSLALSLVSTLAEVHRRDIIHKDIKPSNILLEPSGEARLLDFGLATLQRVEHLDAAPAHLIEGTLAYMSPEQTGRMNRALDYRTDFYSLGVTFYELLTGRRPFQARDALEWFHAHLAQKPKPPHELNPQIPPALSALVLKLLAKVAEERYQSAEGLNVDLERCREALGQGEHEVFPLGTQDTPQRFQLPQRLYGREEQVASLLEGFERVTRTGQPELLLLSGYSGIGKSSLVHELYKPVVRRRGLFLSGKFDQFQRDIPHITLAQTLRELVQQLLAGSEEELARWREQVNRAWDGQGQVLVDLVPQLEVLVGRQPALQELSSSEAQQRFFRVVRQFVSVFSTKEHPAVVFLDDLQWADPSSLQLLEQMQTHPERPPVLWLGAYRDNEVSPTHPLMTMLEKAREAGTRVTNIRLEPLSVEQVKELVGDTLPGARQEVIAPLAGLVHEKTGGNPFFLLRLLVTLHQEGLLVRLPEGGWQWDAEGVRARDYSDNVVDFMVGKLRQFPPDTQHLLRLAACAGTVFSLQLLGTLSGLSSVEEVEQGLEPALREGLLGRVGTETYRFLHDRIQQAAHSLSSEAELQETHLRIGRLMLQNLSPEQVRESLFEVVSQLNAGMALMEDPTERHQLARLNAEAGGKAQAALALRPALTCFSTAFALIPGDPWETDHALTFQVRLSQARTELMTGSPSAAQHLAEQLRPQARTRAATVAVYVLKQDIHFATGRFLEGMNCMLECLGLLGMPVSPHPTREEAVAAHAEVWTLLGQRPIDSLSELPLMTDPDMKMAVTALFKLFPGAYSTDPHLLIIILSRIVSLTLRHGFVDNAVSGYAWFGVITGSFFKRYREGFAFARLALGFVERYNLSTYRGDVLLSMQFSSCWVQPLPRAQEILLNGLRHALQVGGIAPACYCSLYLVANRLAMGHSLDEVYQESLVRGEYLRQTGFVDPQELLLVTQRYVQQLRGHSLSFCTMSGEGFDERAHEARLLKPSRTGTQYNYWVLKMQSRFMCGAYEEARDAADKVAGLLWATPGNLNAREGHFYRALTLAACFEQASPEQRREWLEAIEQHHQQLAEWAENCPENFRALEQLVFAERARLLGRTEEATRAYEQAIRVARENGATQYVGQASELAAKFWRTREAPIVALAFAREARAAYQRWGAEAKVQHLESQWPDLASTPSSQDTSTTSSTDSTRIDALTVVKAQQAISGEIEQERLVTALMRAAMENAGAQKGALLLPGENTLAVAALFQTAPEGALVALGEGQHHELPWTLLNYVQRTREHVLIADAAQPHAFSADAYLARGGARSVLCLPLMRQERFSGALYLENDLATNAFSPARLALLGHLASQAAISIENARLYADVQRARTELRQANDELERRVEERTHELTRAQARLVDTAREVGMAEVAANVLHNVGNVLTSAVVNLEMMSKTAGTLRVSRVKQTGALLLEHREALADFLTKDPRGGQLPDYLVALGDEMMREQTRLMEDMATMNRHIEHIRAIVQVQQAYARHSLMTEECELSQLIDDALRIQLESLRRHGVTVHRELSRVPPVNVDKHKVLQILINLLSNAKQALDGVPEGRRNLWVKLKTRENVALIQVADDGVGIAPELTGSLFTHGFTTRKDGHGFGLHSSALAAQLLKGRLTLESAGLGRGAVATLELPLTPEASLRASS
>NZ_CP022098.1|WP_095984907.1|2235426_2235759_+|hypothetical-protein
MKYLAVRWVHSDPEYPVLRLGEYDGGGWEQRKIDVYRDGRVGFADAHEERDAELALVPMPGLEEIAAETESAPVEITRAEFERLWEQRRAGGAYWKAALLTTTRGDSLRG
>NZ_CP022098.1|WP_157758352.1|2234345_2235278_-|TraB/GumN-family-protein
MRLLRLPLFLVALLATACATPSAQAPATAAVAQPPAFLWEVTRPGAPDKPLYLTGSIHLGLPGQFTFPPSLEAALARSQALVVELDPDKAAANAQETQKLVLRLGLYAPPDGLDAHLSEETRKRLPERLEQVGLPPAAVQRMRPWLLYLTLSVLELQRAGYSEAGGIDRLLLTKARDTKRIVELETMEGQMSTLASLPDPVQELMLRELLEQSPLTSVNMARMTTAWQGGNPDALADLLFTQAKDPAYQPFYEALFYVRNRRMADKLAGMLDAPETHFVVVGAGHLVGPEGLLALLERAGFQVRQLPREP
>NZ_CP022098.1|WP_095984905.1|2233576_2234323_-|response-regulator-transcription-factor
MSPPLRILIADDELVARKRLARLLAALPGTTVCGEVSDAQAVLDTVRAGGVDVVLLDIHMPGLSGLDALALLPEGGPQVILITAHPDHAVEAFEHGAVDYVLKPVEASRLQKALDRARARFSPPPQEPVRLDRLPIPTRQGIVLVAPETISHATLEDELVTVFTAQGEYLTDFSLQELVDRLPTEGFYRVHRRALLNLAQVTRLEPLETGGYLARTARGHTVEVSRQSARELRRRLGLRRGGEEEPGA
>NZ_CP022098.1|WP_095991897.1|2232923_2233532_-|RDD-family-protein
MSEPEISAPQRSGAFCAQHADQRAATLCNRCGNYACEQCFRVAYDRQDYCTECLPRIQPPLAGRRARFAAVVVDQIALIAPIFVCMLLGILLSNGSGTGMISLGLGALGSLGVVGYQFYLLASVGQSLGKRTMGIKVVRTDGTPVDLARLIFLRNVVPVIIGMFTWNLFNLIDTLCIFTEQRRCLHDHIADTQVIVVNNTDA
>NZ_CP022098.1|WP_157758351.1|2231749_2232844_+|diguanylate-cyclase
MSEPVAAKVLVVEDNRTMLALMQYYLSKDFTVFLARSAEEALEVLQREQLHAVVSDQNLGDGLMGVDLLKRVSELQPHAARILVTASQKLEDAQKAINEARVNHFLTKPFTEQELKNTVGQAVHNAALVAIRDKMVQELKEQLGLRPAKPAAGRSPPSSTRIKTVEPRAPDAKGGGNQPLIPESERLAFRDGLTGLYNHRYFQEALSAGLLSARRREQKLMLVLVDIDGFRRFNLSRGYAEGDKLLRRVAQLVTELMEDPVTHARSDNSSEIAARYDWDVFGVVLCNADVERARTYAEKLRKAVEEFDFPEGTGSGQGEVTVSAAISVFPDPARSEQDLISFAEKALRASKLVGPNRVVIANQG
>NZ_CP022098.1|WP_095984903.1|2230162_2231653_+|glutamate--cysteine-ligase
MGLQIDCEKFETQEYESFGERLTESLEVLRALLARPGFGEGPPSLGAELEMFLVDVHGRPLPVNRQVLGQTADPRVTVELNRFNIECNLRPGPLAGRPFSAMRAEFESALAEVARAAATQGARVAVMGILPTLREADLRPGSLTAMPRYRAMSSSIRRSRGEAPFRVVIQGEDPLSLEWDDVTLEGANTSLQYHLRVLPADFARLYNACQLATAPVLAVSGNSPFLLGRRLWDETRVALFRQAVDDRGEGAHEEAPRPGRVSFGHGWVREGAWELFAESVALHPPLLPVLAPASPREHLTGDGLPRLEELRLHQGTVWNWNRAIYDPADGGHLRIEMRALPAGPTVEDMLANGALLLGLTLGLGGEVERLLPSMPFAYAQDNFLRAARHGLDAVLLWPERPGRAPRAHPAPELVRRLLPVAREGLVGAGVDPDEVDALLGIIQARVSAGCTGARWQRKMLACLEAHMPRPDALGALLERYLTHAASGRPVHEWPGA
>NZ_CP022098.1|WP_095984902.1|2228728_2230144_+|hydroxyacylglutathione-hydrolase
MIIERRWDVLVVGGGASGTLLVTQLLRNAPGPLRVALVEREARTGPGLAYSTPHSSHLLNVPVGRMSAFPDDPEHFLRWMRRVEPGTAPGDFVARQRYGQYLEALLRESRRAAAPGVVLELIRGEVSALSEEDGVVRVALAQGPSLEARAVVLALGNAPPADLPVDGGGLFESAHYVRSPWAPRALEHIEPHHSVLLVGTGLTMVDTVLSLAERNHEGRIHALSRHGLLPQVHRPNVQPRPPPRFSEPRSVRALFHALRREIEGLPEGSDWRCVVDGLRPVTSSLWRGLPVPAQRRFLRHLRTLWDVHRHRMASSVADTLAQLRRAGVLHVHAGRLRGFQMLDGGWVEARARPRGVVFEATFRVQHVINCTGPDCSFRGQPLLRSLLESGLARRDALGLGLSTDEGGALLDGQGRASALLFTLGPLRRGELWESMAVPEIRDQAAALARRLWRELAARPDAFASRDVHPLS
>NZ_CP022098.1|WP_095984901.1|2227430_2228522_-|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN
MDASPAALPLVNLYDLPRAALGELLGHWGYSAHYRDLLWTALYRQQVESFDALTGLKPELVATLRERTLLERPTTHHEVFSSDGYTRKLLLRLRDGQTVETVLMRFKGRATVCLSTQAGCAMGCVFCATGQMGFVRHLSPGEIIGQVLHVTRLLRETNETLRNVVLMGMGEPLHNYEGTLAAVDILVDALGLALGPRFITLSTVGVVPGIRRLADEDRPVQLAVSLHGATDAERGALVPAARKWSLAELMDACRYYTHKRKRRIFYEWALISGRNDTPEQAHALGTLLEGMDAHVNLIPLNPTVGYAEQPSGPDSVRAFQDILAGYGLPSTVRQRRGIDIDAGCGQLKAAVERPRPARQPHAS
>NZ_CP022098.1|WP_157758353.1|2252506_2252935_-|hypothetical-protein
MRYNGQILSWEQTQHWRQVLGPPSREQQGILTWDELGVFLYDQDAQIPGPESFMVLLGRARHSTLTQGEPEFWPRKTFSGRLLVDGAAITTRSTLNEINRDKKGVSFDRDYMSGVYSYHVGDFYVRLDYGHDHSLTSFGLDK
>NZ_CP022098.1|WP_157758354.1|2253063_2255802_-|LysM-peptidoglycan-binding-domain-containing-protein
MPPCRVAGQVVAPRYAHEGGSSMVADPRKHSAMYGTPAVPDEFPRGVSNRPPSPGLTPRTHRVRAGDTLSRLALDYHTTVESLVAANRIQDARLLWIGQVLAIPQEAPPTRPQTALPSYPAISPPPRDPSAPNSIPLFRRNQERPRPRAKPSRVSSLVSTWVAVKGETLQSTIALEEMHSLITSTTSDELLSWLRLIFGEDIPRTAIQRLRAAVLDGSLPQPQLIIVRDELDGHPAAYHGQSRSILVSRELVLRARSDNNEAWKLLVCLIEEFGHHLDQLLRTHYSSVGGDALLDEGARMAYALIDFGYNRGQRRREFAQYTMAEGTANLGVEFAEMTEAVQRFVSAPEQWEDSRSDNLEYFGAGRGSGRAGSYGHESIEDALEDAGFRLKERRAVYFGNWLRDHSQLVDPKLVRKKGAPVTTGLSRETITRIVDVIAREKFGNEKYLNEPVFRVDTQRLGVYRNEEHIDNPNGITDARAIDPAFRGACRAEELAINSLRMKNFIRTGSISGGRASRTHRVKDGDTLDSIARSHGLTWQELARFNFGTDVKDEVSRQLYTKVGCRKKTHDGRSYIFTSQDSPGLIQIPGVKAGQVQEAPYSAFHYMSTQLRTAVKLGRSNAGYRHFGHALHTLEDFFSHTNFVELMLIHLGAWVEPWVPAQGAKAGDASSLPLTSGQFGGLDTLASLTLGIAESMQKVSECIAGEMTSGTKIALILLEDQGYTEVRDMMGGLLERLHKLEKAHPTIATLSCETIGMVLRSAKATMGGSIHFVASLIDDAQTAFLSDPSSTNPTHTQLAKDHDDHPLHALAANLAAGAVLDVGKVIQKAWNGEATADDVVLTASRYFLHPALIDPHGNAGWMRGHVQVWIPGHRAAIASMGSKSWAAEWTKESSQHLRTMMDRARILMGRGRP
>NZ_CP022098.1|WP_095984913.1|2255838_2256522_-|ligase-associated-DNA-damage-response-endonuclease-PdeM
MAARGLPVRLGGTEVELRPERALYWPEAGVLAVADLHWGKPESFHQHGIPLPTGVLEDDLARLSAALHTTGARRVLLVGDLIHSRRGLTADVVERVAAWREGHDVELVLVRGNHDRHLEALPPSWRMRLVESHLDEGPFRFAHHPEPVPGRYVCAGHLHPTVRLSTGADRLRLPCFHLGPQVGVLPAFSAFTGGLDMRAGAGERLFVIAEDAVVELPPAHSARRSWS
>NZ_CP022098.1|WP_095991898.1|2256491_2258954_-|ligase-associated-DNA-damage-response-DEXH-box-helicase
MRKVAPPPSPEAHALGVDAWFESRGWTPFPFQREAWAAYARGESGLIHVPTGAGKTYAAYIGPLTEVAERREKGLQILYITPLRAVSRDIELALLAPLSAFDADITVESRTGDTSSGIRRKQKDRLPEVLITTPESLSLLLCHERAHELFAPLRCVIVDEWHELLGTKRGTQVELALARLRRFAPGMRTWALSATLANLDEAARAAVGPNATPSFVSAGLERPVHMETLLPDSVDAFPWAGHLGMTMLRKVSDWLDPAHPTLLFTNTRSQAERWYEGLRFLRPEWEGVLALHHGSIDRDSREAVERGLKDGSVRLVVCTSSLDLGVDFGPVERVVQIGSPKGISRTLQRAGRSAHRPGATAHLLFIPTHALELVEMAAARDALAHREVEPRAPLRQPLDVLAQHLVTCALGGGFVREALLSEVRDTLAYCDLSEEDFDRALLLVTEGGPTLRAYPQFHRVRRVEDRYVVADARVARLHRLNVGTIASDATVELRYWTGGRIGTVEESFVSRLRPGDTFLFAGKRLEFSRMKDLTAYVKAAKQRASATPRWSGGRLPLSGSLAAAVRRTFHAVREGHLDAAELRAARPVLDAQARLSRVPAQDACLVELCRTREGHHLFLYPFEGRLVHEGLAALLALRLTRLQKATFSLAVNDYGLELLSPSPFPFEEALRPALFTRERLVEDILESVNLGELARRQFRDVARVAGLVMPGLPGARKSTRQIQASTGLLYDVFARYEPDHMLLAQARREVLEQHFEQVRLVSTLERLERTPLECVHVPRPTPLAFPLVVERMGATLSNETLLDRVQRMKEKWLREDSLSA
>NZ_CP022098.1|WP_095984914.1|2259003_2260599_-|ATP-dependent-DNA-ligase
MRRLVDLYEALDSTTSTNAKVDALVDYFRRTPPEDAAWGLFFLTGRRIKRLVPSKALKQWARELSDTPEWLFDEAYASVGDLAEIIALLLDSAEQPQVTEELPLSRWMEERILPLGGLALPEQRERITGWWHTLPRRELFVFNKMLTGELRVGVSDTLVVRALAQYAGLPPAAVSHRLMGTWAPSRAFFEQLIAPDVSDGDRSRPYPFYLASPLEQPVEGLGDRSEWMVEWKWDGIRGQLIHRQGGIYLWSRGEELVTERYPEIAKAAASLPPGTVLDGEILAYEDGKPLPFARLQRRIGRQKLTAKVLAEAPAVFMAYDLLEEKGEDLRPLPLRERRARLEALLRDKPRFPISPRVPADTWEELAQARRESRERNVEGFMIKRLESPYQHGRKRGDWWKWKIDPFTVDAVLLYAHPGHGKRAALYTDYTFAVWKGEELLPVAKAYSGLTDEEISRLDRWIRAHTKEKFGPVRSVEPAQVFELHFEGIAASPRHKSGVALRFPRIARWRSDKAPKDADSLDQLKELIHAPT
>NZ_CP022098.1|WP_095991899.1|2260604_2261624_-|ligase-associated-DNA-damage-response-exonuclease
MARSATRQPLVTVTPEGLYCPQGDFHIDAWRPVSRTLITHAHGDHARWGSQQYLGTRPSRGLLRKRLGADADITTLDYGECLTLGGVTVSFHPAGHVLGSAQIRLEYKDEVWVVSGDYKRDADPTCQPFEVVPCDTFITEATFGLPIYRWDDTRRVAEEVLHWWDANREAGRASVLFCYALGKAQRLLAELARVTDREVFVHGATHALVELYREASVPMLPTRPVSEAEKGTSYAGALVLAPPSSAGSTWMRRFGEHETGFASGWMRVRGNRRRRGYDRGFVLSDHADWPGLLRTAKETGASRVLATHGSSDTLSRYLRENLGIDAAPLATPFEGEAED
>NZ_CP022098.1|WP_095984915.1|2261723_2261975_-|hypothetical-protein
MDEKEYLNRRMGIPLDPAKQKDPEEHGDRVPAEGRAEHLNDITEQNGGQRSEVGPPWHDTSLERGLSDEFDKHGGRGKPKKKR
>NZ_CP022098.1|WP_095984916.1|2262121_2262889_-|ROK-family-protein
MSQKAPQPSPRKKTVRETHATGPRTLAIDIGGSGLKALVLGPEGTALDERRRVKTPKPATPKAVLRALEKLIKPLGAFERVSVGFPGVVEEGVTKSAHNLHPDWTGFNLAEALHQLTKRPVRVLNDAGVQGFGVIEGKGLEMVLTLGTGMGCALYIDGKYVPNLELAHHPFHGGKTYEDYVGQAALERVGKKKWNKHVERVLQQIQPIWNPRQIYVGGGNARLLDIKLPPNVKITENIAGLLGGFALWKDEPRQR
>NZ_CP022098.1|WP_095984917.1|2263138_2263636_+|folate-biosynthesis-protein
MARTTTIELHKEDMKFAAGHFTIFSATHRENMHGHNFAVFVSLTGEVLDNGMLADYDIFKRMALEQCRAWNETFMLPAHSRHLQVERDARGDVIARFNGEELRFLSRDVTILPVENVSLEELSRLFGEKLVGDGELMRTSRISRVVVKCSSEPGQNCSWEWNSHG
>NZ_CP022098.1|WP_095984918.1|2263628_2264336_+|SDR-family-oxidoreductase
MADWAIITGASRGIGRAAAVRFLQAGWRVMNVSRRPCPEPGVVNVLADLSTPGWEATFTPALSTALGSSPGRVCLVHNAALYGHDDALSLDAEHLRRVLEVNVVAPATLNRLVRGYLTDGSSILYVGSTLSEKAVRGAASYVTSKHALAGLMRSTCQDLVGTRVHTVCVCPGFTDTEMMRENVGDSEAARANTAARMTYGRLIAPEEIADVLLRCAEMPVFNGAVLHANLGQIET

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_8

2249124-2249696

Orphan

Consensus_repeat	Method
GGGCCTCGCGGGCATTGGCTTCGGCG	CRISPRCasFinder

11 spacers

The CRISPR arrays of NZ_CP022098_8

>merge|NZ_CP022098|8|2249124-2249696|CRISPRCasFinder
GTGCTTCAAGGGCATTCTTCTCGGCGATTTCCTGCTGAGCGCGTGCTCTCAAGGCATTGGCCTCGGAGAGATCCTTCTGGATCAGGACCTCACGGGCATTGGCCTCGGCGGTCCGCTGCTGTTCGAGTGCTTTCTGGGCATTGGTCTCAGCGAGTTGCTGCTGTTCGAGTGCTTTCTGGGCATTGACTTCGGCGGTCCGCTGCTGCCGCTGGGCCTCTCGCGCATTCGCTTCGGCGTTCTCCTGCTGCCGCTGAGCCTCCCGCGCATTGGCCTCGGCCGCCTCCTGTTGTCTGCGCGCTTCCCGGGCATTGGACTCGGAGGAGTTCCTCTGGGAGAGGGCTTCCCGGGCGTTGAGTTCGGCGAGGTACTGCTGCTCGCGCGCTCTCTGTGCATTTTCCTCGGCGAGTTCCCGCTGCCGCTGGGCCTCGCGGGCATTGGCTTCGGCGAGGCGCTTCTGGGCCAGGGCCTCGTGGGCATTGGCTTCGGCGAGGCGCTTCTGGGTCAGGGCCTCGCGGGCATTGGCCTCGGCGCGGTATTGCTGCTCGAGTGCCTCGCGGGCATGGCGCTCGGAGG

>NZ_CP022098|8|8|2249124-2249696|CRISPRCasFinder
GTGCTTCAAGGGCATTCTTCTCGGCG	ATTTCCTGCTGAGCGCGTGCTCTCAAGGCATTGGCCTCGGAGAGATCCTTCTGGATCA
GGACCTCACGGGCATTGGCCTCGGCG	GTCCGCTGCTGTTCGA
GTGCTTTCTGGGCATTGGTCTCAGCG	AGTTGCTGCTGTTCGA
GTGCTTTCTGGGCATTGACTTCGGCG	GTCCGCTGCTGCCGCT
GGGCCTCTCGCGCATTCGCTTCGGCG	TTCTCCTGCTGCCGCT
GAGCCTCCCGCGCATTGGCCTCGGCC	GCCTCCTGTTGTCTGC
GCGCTTCCCGGGCATTGGACTCGGAG	GAGTTCCTCTGGGAGA
GGGCTTCCCGGGCGTTGAGTTCGGCG	AGGTACTGCTGCTCGCGCGCTCTCTGTGCATTTTCCTCGGCGAGTTCCCGCTGCCGCT
GGGCCTCGCGGGCATTGGCTTCGGCG	AGGCGCTTCTGGGCCA
GGGCCTCGTGGGCATTGGCTTCGGCG	AGGCGCTTCTGGGTCA
GGGCCTCGCGGGCATTGGCCTCGGCG	CGGTATTGCTGCTCGA
GTGCCTCGCGGGCATGGCGCTCGGAGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_095991897.1\|2232923_2233532_-\|RDD-family-protein	unknown	unknown	gnl\|CDD\|377640
NZ_CP022098.1\|WP_095984905.1\|2233576_2234323_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225818
NZ_CP022098.1\|WP_157758352.1\|2234345_2235278_-\|TraB/GumN-family-protein	unknown	unknown	gnl\|CDD\|350614
NZ_CP022098.1\|WP_095984903.1\|2230162_2231653_+\|glutamate--cysteine-ligase	unknown	unknown	gnl\|CDD\|225081
NZ_CP022098.1\|WP_095984902.1\|2228728_2230144_+\|hydroxyacylglutathione-hydrolase	unknown	unknown	gnl\|CDD\|226906
NZ_CP022098.1\|WP_095984907.1\|2235426_2235759_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095984917.1\|2263138_2263636_+\|folate-biosynthesis-protein	unknown	unknown	gnl\|CDD\|223792
NZ_CP022098.1\|WP_095984915.1\|2261723_2261975_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095984909.1\|2241258_2246580_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|226415
NZ_CP022098.1\|WP_157758351.1\|2231749_2232844_+\|diguanylate-cyclase	unknown	unknown	gnl\|CDD\|143635
NZ_CP022098.1\|WP_095991898.1\|2256491_2258954_-\|ligase-associated-DNA-damage-response-DEXH-box-helicase	unknown	unknown	gnl\|CDD\|274994
NZ_CP022098.1\|WP_095984901.1\|2227430_2228522_-\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	unknown	unknown	gnl\|CDD\|223890
NZ_CP022098.1\|WP_095984908.1\|2235724_2241046_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|226415
NZ_CP022098.1\|WP_157758354.1\|2253063_2255802_-\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|369266
NZ_CP022098.1\|WP_095984913.1\|2255838_2256522_-\|ligase-associated-DNA-damage-response-endonuclease-PdeM	unknown	unknown	gnl\|CDD\|274996
NZ_CP022098.1\|WP_095991899.1\|2260604_2261624_-\|ligase-associated-DNA-damage-response-exonuclease	unknown	unknown	gnl\|CDD\|274995
NZ_CP022098.1\|WP_095984916.1\|2262121_2262889_-\|ROK-family-protein	unknown	unknown	gnl\|CDD\|224851
NZ_CP022098.1\|WP_095984918.1\|2263628_2264336_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212491
NZ_CP022098.1\|WP_095984914.1\|2259003_2260599_-\|ATP-dependent-DNA-ligase	unknown	unknown	gnl\|CDD\|236428
NZ_CP022098.1\|WP_157758353.1\|2252506_2252935_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095991897.1\|2232923_2233532_-\|RDD-family-protein	gnl\|CDD\|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	3.96204e-19
NZ_CP022098.1\|WP_095984905.1\|2233576_2234323_-\|response-regulator-transcription-factor	gnl\|CDD\|225818	COG3279, LytT, Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms].	3.96569e-51
NZ_CP022098.1\|WP_157758352.1\|2234345_2235278_-\|TraB/GumN-family-protein	gnl\|CDD\|350614	cd14789, Tiki, Tiki homology domain antagonizes Wnt function via cleavage of amino-terminal residues. Tiki is a membrane-associated metalloprotease that inhibits Wnt via the cleavage of its amino terminus, diminishing Wnt's binding to receptors. Wnt is essential in animal development and homeostasis. In xenopus, tiki is critical in head development. In human cells, TIKI inhibits Wnt-signaling, which is important in embryogenesis, homeostasis, and regeneration. Deregulation of WNT contributes to birth defects, cancer and various diseases. TIKI homology domains are part of the TraB family and are related to the Erythromycin esterase, GumN plant pathogens, RtxA toxins, and Campylobacter Jejuni heme-binding, Chan-like proteins. TraB/PrgY are identified in gut bacterium Enterococcus faecalis, but its function has not been well characterized. Plasmid-borne, TraB has been implicated in the regulation of pheromone sensitivity and specificity. Based on homology to TIKI activity, it has been proposed that TraB acts as a metalloprotease in the inactivation of mating pheromone. The TIKI/TraB family has 2 conserved GxxH motifs and conserved glutamate and arginine residues that may be catalytic.	2.83806e-81
NZ_CP022098.1\|WP_157758354.1\|2253063_2255802_-\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|369266	pfam07217, Het-C, Heterokaryon incompatibility protein Het-C. In filamentous fungi, het loci (for heterokaryon incompatibility) are believed to regulate self/nonself-recognition during vegetative growth. As filamentous fungi grow, hyphal fusion occurs within an individual colony to form a network. Hyphal fusion can occur also between different individuals to form a heterokaryon, in which genetically distinct nuclei occupy a common cytoplasm. However, heterokaryotic cells are viable only if the individuals involved have identical alleles at all het loci.	3.00276e-28
NZ_CP022098.1\|WP_095984902.1\|2228728_2230144_+\|hydroxyacylglutathione-hydrolase	gnl\|CDD\|226906	COG4529, COG4529, Uncharacterized protein conserved in bacteria [Function unknown].	7.60255e-93
NZ_CP022098.1\|WP_095984917.1\|2263138_2263636_+\|folate-biosynthesis-protein	gnl\|CDD\|223792	COG0720, COG0720, 6-pyruvoyl-tetrahydropterin synthase [Coenzyme metabolism].	2.65823e-07
NZ_CP022098.1\|WP_095984909.1\|2241258_2246580_-\|AAA-family-ATPase	gnl\|CDD\|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	9.2985e-137
NZ_CP022098.1\|WP_157758351.1\|2231749_2232844_+\|diguanylate-cyclase	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.91018e-38
NZ_CP022098.1\|WP_095991898.1\|2256491_2258954_-\|ligase-associated-DNA-damage-response-DEXH-box-helicase	gnl\|CDD\|274994	TIGR04121, ATP-dependent_helicase, DEXH box helicase, DNA ligase-associated. Members of this protein family are DEAD/DEAH box helicases found associated with a bacterial ATP-dependent DNA ligase, part of a four-gene system that occurs in about 12 % of prokaryotic reference genomes. The actual motif in this family is DE[VILW]H.	0
NZ_CP022098.1\|WP_095984901.1\|2227430_2228522_-\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	gnl\|CDD\|223890	COG0820, COG0820, Predicted Fe-S-cluster redox enzyme [General function prediction only].	5.74009e-128
NZ_CP022098.1\|WP_095984908.1\|2235724_2241046_-\|AAA-family-ATPase	gnl\|CDD\|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	2.71811e-136
NZ_CP022098.1\|WP_095984903.1\|2230162_2231653_+\|glutamate--cysteine-ligase	gnl\|CDD\|225081	COG2170, COG2170, Uncharacterized conserved protein [Function unknown].	4.35698e-08
NZ_CP022098.1\|WP_095984913.1\|2255838_2256522_-\|ligase-associated-DNA-damage-response-endonuclease-PdeM	gnl\|CDD\|274996	TIGR04123, hypothetical_protein, metallophosphoesterase, DNA ligase-associated. Members of this protein family are an uncharacterized putative metallophosphoesterase associated with a DNA ligase, a helicase, and a putative exonuclease. It may play a role in DNA repair. Its system is present in about 12 % of prokaryotic reference genomes.	1.83495e-83
NZ_CP022098.1\|WP_095984918.1\|2263628_2264336_+\|SDR-family-oxidoreductase	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	3.42238e-40
NZ_CP022098.1\|WP_095984916.1\|2262121_2262889_-\|ROK-family-protein	gnl\|CDD\|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	1.75615e-22
NZ_CP022098.1\|WP_095991899.1\|2260604_2261624_-\|ligase-associated-DNA-damage-response-exonuclease	gnl\|CDD\|274995	TIGR04122, hypothetical_protein, putative exonuclease, DNA ligase-associated. Members of this protein family frequently are found annotated as a putative exonuclease involved in mRNA processing. This protein is found, exclusively in bacteria, associated with three other proteins: an ATP-dependent DNA ligase, a helicase, and putative phosphoesterase.	0
NZ_CP022098.1\|WP_095984914.1\|2259003_2260599_-\|ATP-dependent-DNA-ligase	gnl\|CDD\|236428	PRK09247, PRK09247, ATP-dependent DNA ligase; Validated.	0

>NZ_CP022098.1|WP_095984909.1|2241258_2246580_-|AAA-family-ATPase
MLDIPGYRVLGTLRATGSNVLFHAVREADGVRVILKTPMAPSPGASENERYRREFAILQRLRDVRGVPRPYAHERIHERPVLLLERVQGETLSETTGQPMEVSRFLSLALSLVSTLAEVHGHDIIHKDIKPSNILLEPSGEARLLDFGLATLQRVEHLDAAPAHLIEGTLAYMSPEQTGRMNRAVDHRTDFYSLGVTFYELLTGRRPFQARDALEWFHAHLAQKPKPPHELNPQVPPPLSALVMKLLAKVAEERYQSAEGLNVDLERCREALGQGEHEVFPLGTQDTPQRFQLPQRLYGREEQVASLLEGFERVTRTGRPELLLLRGYSGIGKSSLVHELYKPVVRRRALFLHGKFDQFQRDIPYVTLAQTLRELLRQLLAGSEEELARWREQVNRAWDGQGQVLVDLVPQLEVLVGRQPALQELSSSEAQQRFFRVVRQFVSVFSTKEHPSVVFLDDLQWADPASLRLLEQMLSHPEGPPVLWLGAYRDNEVSPTHPLMAVVEKVREAGARLTDIRLEPLHVEHVEQLVDETLPGARQEVIAPLAGLVHEKTGGNPFFLRQLLVTLHQEGLLVRLPKEGWRWDAQGVRARGYSDNVVDFMVGKLRQLPPGTQHLLRLAACSGTVFSLQLLGTLSGLSAVEVVEQGLEPALREGLLGRVGTETYRFLHDRIQQAAHSLSSEAERQETHLRIGRLMLQNLSPEQVRESLFEVVSQLNAGMALMEDPTERHQLARLNAEAGGKAQAALALRPALTCFSTAFALIPGDPWETDHALAFQVRLAQARTELMSGSPSGAQRQLEELRPRTRTRADTVALYLLTQDIHFATGAFLEGMSCLRECLELLGMPVPRHPTWEEAVAAHEEAWALLGQRPIDSLLELPLMTDPDMKMAVVSLFKLFPGAYSSDPHLLIIILSRIVSLTLRHGVVDAAVPGYTWFGVITGSFFKRYREGFAFARLALGFVERYHLSARRGDVLLGMQFSSYWVQPLARAQELLLNSLRHALQVGDIAPATYCSVYLVNNRLAMGHSLDEVHQESLVRDEFLRQTGFVDPQEALLVSQRYVQQLRGHSLSFSTLSGEGFDERAYEARMTPERLGGTRCHYWLHKMQSRFMCGAYEEAREAADKTAGLLWSCFGTLNAREGHFYRALTLAACFEGATPERQREWLEAIGQHHQQLAEWAENCPENFRALERLVFAERARLLGRSEDATRAYEQAIRSARENGAIQYVGLASELAAKFWRTREAPIVAHAFAREARAAYQRWGARAKVHHLESQWPELTSTPSPQDSLSTSSTDSTHIDALTVVKAQQAISGEMEQERLVTALMRAAMENAGAQRGALLLPDGDALSVAALFQLSPEGTLVASDEAGHHELPWTLLAYVRRTSEHVLIADAAQPHAFSSDAYLARGEARSVLCLPLMRREQFSGALYLENDLATNAFSPARLALLGHLASQAAISIENARLYADVQRARTELRQANDELERRVEERTRELKQTQARLVDTAREVGMAEVASNVLHNVGNVLTSAVVNLEMMSRTAGALRVGRVRQTGTLLLEHREALADFLTKDPRGGQLPDYLVALGDEMMREQTRLMEDMATMNRHVEHIRAIVQVQQTYARHSLMTEECELSQLVDDALRIQLESLRRHGVTVHRELSRVPRVKVDKHKVLQILINLLSNAKHALDGVPEGQRNLWVRLAAEGNVARIQVADDGVGIAPELMDSLFAHGFTTRKDGHGFGLHSSALAAQLLKGRLTLESAGLGQGAVATLELPLTSEGSPRASS
>NZ_CP022098.1|WP_095984908.1|2235724_2241046_-|AAA-family-ATPase
MLDIPGYRVLGTLRATGSNVLFHAVREADGVSVILKTPMSPSPGASENERYRREFAILRRLQDVRGVASAYSCERIHERPVLLLERGRGEPLSESSGQPMEVSRFLSLALSLVSTLAEVHRRDIIHKDIKPSNILLEPSGEARLLDFGLATLQRVEHLDAAPAHLIEGTLAYMSPEQTGRMNRALDYRTDFYSLGVTFYELLTGRRPFQARDALEWFHAHLAQKPKPPHELNPQIPPALSALVLKLLAKVAEERYQSAEGLNVDLERCREALGQGEHEVFPLGTQDTPQRFQLPQRLYGREEQVASLLEGFERVTRTGQPELLLLSGYSGIGKSSLVHELYKPVVRRRGLFLSGKFDQFQRDIPHITLAQTLRELVQQLLAGSEEELARWREQVNRAWDGQGQVLVDLVPQLEVLVGRQPALQELSSSEAQQRFFRVVRQFVSVFSTKEHPAVVFLDDLQWADPSSLQLLEQMQTHPERPPVLWLGAYRDNEVSPTHPLMTMLEKAREAGTRVTNIRLEPLSVEQVKELVGDTLPGARQEVIAPLAGLVHEKTGGNPFFLLRLLVTLHQEGLLVRLPEGGWQWDAEGVRARDYSDNVVDFMVGKLRQFPPDTQHLLRLAACAGTVFSLQLLGTLSGLSSVEEVEQGLEPALREGLLGRVGTETYRFLHDRIQQAAHSLSSEAELQETHLRIGRLMLQNLSPEQVRESLFEVVSQLNAGMALMEDPTERHQLARLNAEAGGKAQAALALRPALTCFSTAFALIPGDPWETDHALTFQVRLSQARTELMTGSPSAAQHLAEQLRPQARTRAATVAVYVLKQDIHFATGRFLEGMNCMLECLGLLGMPVSPHPTREEAVAAHAEVWTLLGQRPIDSLSELPLMTDPDMKMAVTALFKLFPGAYSTDPHLLIIILSRIVSLTLRHGFVDNAVSGYAWFGVITGSFFKRYREGFAFARLALGFVERYNLSTYRGDVLLSMQFSSCWVQPLPRAQEILLNGLRHALQVGGIAPACYCSLYLVANRLAMGHSLDEVYQESLVRGEYLRQTGFVDPQELLLVTQRYVQQLRGHSLSFCTMSGEGFDERAHEARLLKPSRTGTQYNYWVLKMQSRFMCGAYEEARDAADKVAGLLWATPGNLNAREGHFYRALTLAACFEQASPEQRREWLEAIEQHHQQLAEWAENCPENFRALEQLVFAERARLLGRTEEATRAYEQAIRVARENGATQYVGQASELAAKFWRTREAPIVALAFAREARAAYQRWGAEAKVQHLESQWPDLASTPSSQDTSTTSSTDSTRIDALTVVKAQQAISGEIEQERLVTALMRAAMENAGAQKGALLLPGENTLAVAALFQTAPEGALVALGEGQHHELPWTLLNYVQRTREHVLIADAAQPHAFSADAYLARGGARSVLCLPLMRQERFSGALYLENDLATNAFSPARLALLGHLASQAAISIENARLYADVQRARTELRQANDELERRVEERTHELTRAQARLVDTAREVGMAEVAANVLHNVGNVLTSAVVNLEMMSKTAGTLRVSRVKQTGALLLEHREALADFLTKDPRGGQLPDYLVALGDEMMREQTRLMEDMATMNRHIEHIRAIVQVQQAYARHSLMTEECELSQLIDDALRIQLESLRRHGVTVHRELSRVPPVNVDKHKVLQILINLLSNAKQALDGVPEGRRNLWVKLKTRENVALIQVADDGVGIAPELTGSLFTHGFTTRKDGHGFGLHSSALAAQLLKGRLTLESAGLGRGAVATLELPLTPEASLRASS
>NZ_CP022098.1|WP_095984907.1|2235426_2235759_+|hypothetical-protein
MKYLAVRWVHSDPEYPVLRLGEYDGGGWEQRKIDVYRDGRVGFADAHEERDAELALVPMPGLEEIAAETESAPVEITRAEFERLWEQRRAGGAYWKAALLTTTRGDSLRG
>NZ_CP022098.1|WP_157758352.1|2234345_2235278_-|TraB/GumN-family-protein
MRLLRLPLFLVALLATACATPSAQAPATAAVAQPPAFLWEVTRPGAPDKPLYLTGSIHLGLPGQFTFPPSLEAALARSQALVVELDPDKAAANAQETQKLVLRLGLYAPPDGLDAHLSEETRKRLPERLEQVGLPPAAVQRMRPWLLYLTLSVLELQRAGYSEAGGIDRLLLTKARDTKRIVELETMEGQMSTLASLPDPVQELMLRELLEQSPLTSVNMARMTTAWQGGNPDALADLLFTQAKDPAYQPFYEALFYVRNRRMADKLAGMLDAPETHFVVVGAGHLVGPEGLLALLERAGFQVRQLPREP
>NZ_CP022098.1|WP_095984905.1|2233576_2234323_-|response-regulator-transcription-factor
MSPPLRILIADDELVARKRLARLLAALPGTTVCGEVSDAQAVLDTVRAGGVDVVLLDIHMPGLSGLDALALLPEGGPQVILITAHPDHAVEAFEHGAVDYVLKPVEASRLQKALDRARARFSPPPQEPVRLDRLPIPTRQGIVLVAPETISHATLEDELVTVFTAQGEYLTDFSLQELVDRLPTEGFYRVHRRALLNLAQVTRLEPLETGGYLARTARGHTVEVSRQSARELRRRLGLRRGGEEEPGA
>NZ_CP022098.1|WP_095991897.1|2232923_2233532_-|RDD-family-protein
MSEPEISAPQRSGAFCAQHADQRAATLCNRCGNYACEQCFRVAYDRQDYCTECLPRIQPPLAGRRARFAAVVVDQIALIAPIFVCMLLGILLSNGSGTGMISLGLGALGSLGVVGYQFYLLASVGQSLGKRTMGIKVVRTDGTPVDLARLIFLRNVVPVIIGMFTWNLFNLIDTLCIFTEQRRCLHDHIADTQVIVVNNTDA
>NZ_CP022098.1|WP_157758351.1|2231749_2232844_+|diguanylate-cyclase
MSEPVAAKVLVVEDNRTMLALMQYYLSKDFTVFLARSAEEALEVLQREQLHAVVSDQNLGDGLMGVDLLKRVSELQPHAARILVTASQKLEDAQKAINEARVNHFLTKPFTEQELKNTVGQAVHNAALVAIRDKMVQELKEQLGLRPAKPAAGRSPPSSTRIKTVEPRAPDAKGGGNQPLIPESERLAFRDGLTGLYNHRYFQEALSAGLLSARRREQKLMLVLVDIDGFRRFNLSRGYAEGDKLLRRVAQLVTELMEDPVTHARSDNSSEIAARYDWDVFGVVLCNADVERARTYAEKLRKAVEEFDFPEGTGSGQGEVTVSAAISVFPDPARSEQDLISFAEKALRASKLVGPNRVVIANQG
>NZ_CP022098.1|WP_095984903.1|2230162_2231653_+|glutamate--cysteine-ligase
MGLQIDCEKFETQEYESFGERLTESLEVLRALLARPGFGEGPPSLGAELEMFLVDVHGRPLPVNRQVLGQTADPRVTVELNRFNIECNLRPGPLAGRPFSAMRAEFESALAEVARAAATQGARVAVMGILPTLREADLRPGSLTAMPRYRAMSSSIRRSRGEAPFRVVIQGEDPLSLEWDDVTLEGANTSLQYHLRVLPADFARLYNACQLATAPVLAVSGNSPFLLGRRLWDETRVALFRQAVDDRGEGAHEEAPRPGRVSFGHGWVREGAWELFAESVALHPPLLPVLAPASPREHLTGDGLPRLEELRLHQGTVWNWNRAIYDPADGGHLRIEMRALPAGPTVEDMLANGALLLGLTLGLGGEVERLLPSMPFAYAQDNFLRAARHGLDAVLLWPERPGRAPRAHPAPELVRRLLPVAREGLVGAGVDPDEVDALLGIIQARVSAGCTGARWQRKMLACLEAHMPRPDALGALLERYLTHAASGRPVHEWPGA
>NZ_CP022098.1|WP_095984902.1|2228728_2230144_+|hydroxyacylglutathione-hydrolase
MIIERRWDVLVVGGGASGTLLVTQLLRNAPGPLRVALVEREARTGPGLAYSTPHSSHLLNVPVGRMSAFPDDPEHFLRWMRRVEPGTAPGDFVARQRYGQYLEALLRESRRAAAPGVVLELIRGEVSALSEEDGVVRVALAQGPSLEARAVVLALGNAPPADLPVDGGGLFESAHYVRSPWAPRALEHIEPHHSVLLVGTGLTMVDTVLSLAERNHEGRIHALSRHGLLPQVHRPNVQPRPPPRFSEPRSVRALFHALRREIEGLPEGSDWRCVVDGLRPVTSSLWRGLPVPAQRRFLRHLRTLWDVHRHRMASSVADTLAQLRRAGVLHVHAGRLRGFQMLDGGWVEARARPRGVVFEATFRVQHVINCTGPDCSFRGQPLLRSLLESGLARRDALGLGLSTDEGGALLDGQGRASALLFTLGPLRRGELWESMAVPEIRDQAAALARRLWRELAARPDAFASRDVHPLS
>NZ_CP022098.1|WP_095984901.1|2227430_2228522_-|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN
MDASPAALPLVNLYDLPRAALGELLGHWGYSAHYRDLLWTALYRQQVESFDALTGLKPELVATLRERTLLERPTTHHEVFSSDGYTRKLLLRLRDGQTVETVLMRFKGRATVCLSTQAGCAMGCVFCATGQMGFVRHLSPGEIIGQVLHVTRLLRETNETLRNVVLMGMGEPLHNYEGTLAAVDILVDALGLALGPRFITLSTVGVVPGIRRLADEDRPVQLAVSLHGATDAERGALVPAARKWSLAELMDACRYYTHKRKRRIFYEWALISGRNDTPEQAHALGTLLEGMDAHVNLIPLNPTVGYAEQPSGPDSVRAFQDILAGYGLPSTVRQRRGIDIDAGCGQLKAAVERPRPARQPHAS
>NZ_CP022098.1|WP_157758353.1|2252506_2252935_-|hypothetical-protein
MRYNGQILSWEQTQHWRQVLGPPSREQQGILTWDELGVFLYDQDAQIPGPESFMVLLGRARHSTLTQGEPEFWPRKTFSGRLLVDGAAITTRSTLNEINRDKKGVSFDRDYMSGVYSYHVGDFYVRLDYGHDHSLTSFGLDK
>NZ_CP022098.1|WP_157758354.1|2253063_2255802_-|LysM-peptidoglycan-binding-domain-containing-protein
MPPCRVAGQVVAPRYAHEGGSSMVADPRKHSAMYGTPAVPDEFPRGVSNRPPSPGLTPRTHRVRAGDTLSRLALDYHTTVESLVAANRIQDARLLWIGQVLAIPQEAPPTRPQTALPSYPAISPPPRDPSAPNSIPLFRRNQERPRPRAKPSRVSSLVSTWVAVKGETLQSTIALEEMHSLITSTTSDELLSWLRLIFGEDIPRTAIQRLRAAVLDGSLPQPQLIIVRDELDGHPAAYHGQSRSILVSRELVLRARSDNNEAWKLLVCLIEEFGHHLDQLLRTHYSSVGGDALLDEGARMAYALIDFGYNRGQRRREFAQYTMAEGTANLGVEFAEMTEAVQRFVSAPEQWEDSRSDNLEYFGAGRGSGRAGSYGHESIEDALEDAGFRLKERRAVYFGNWLRDHSQLVDPKLVRKKGAPVTTGLSRETITRIVDVIAREKFGNEKYLNEPVFRVDTQRLGVYRNEEHIDNPNGITDARAIDPAFRGACRAEELAINSLRMKNFIRTGSISGGRASRTHRVKDGDTLDSIARSHGLTWQELARFNFGTDVKDEVSRQLYTKVGCRKKTHDGRSYIFTSQDSPGLIQIPGVKAGQVQEAPYSAFHYMSTQLRTAVKLGRSNAGYRHFGHALHTLEDFFSHTNFVELMLIHLGAWVEPWVPAQGAKAGDASSLPLTSGQFGGLDTLASLTLGIAESMQKVSECIAGEMTSGTKIALILLEDQGYTEVRDMMGGLLERLHKLEKAHPTIATLSCETIGMVLRSAKATMGGSIHFVASLIDDAQTAFLSDPSSTNPTHTQLAKDHDDHPLHALAANLAAGAVLDVGKVIQKAWNGEATADDVVLTASRYFLHPALIDPHGNAGWMRGHVQVWIPGHRAAIASMGSKSWAAEWTKESSQHLRTMMDRARILMGRGRP
>NZ_CP022098.1|WP_095984913.1|2255838_2256522_-|ligase-associated-DNA-damage-response-endonuclease-PdeM
MAARGLPVRLGGTEVELRPERALYWPEAGVLAVADLHWGKPESFHQHGIPLPTGVLEDDLARLSAALHTTGARRVLLVGDLIHSRRGLTADVVERVAAWREGHDVELVLVRGNHDRHLEALPPSWRMRLVESHLDEGPFRFAHHPEPVPGRYVCAGHLHPTVRLSTGADRLRLPCFHLGPQVGVLPAFSAFTGGLDMRAGAGERLFVIAEDAVVELPPAHSARRSWS
>NZ_CP022098.1|WP_095991898.1|2256491_2258954_-|ligase-associated-DNA-damage-response-DEXH-box-helicase
MRKVAPPPSPEAHALGVDAWFESRGWTPFPFQREAWAAYARGESGLIHVPTGAGKTYAAYIGPLTEVAERREKGLQILYITPLRAVSRDIELALLAPLSAFDADITVESRTGDTSSGIRRKQKDRLPEVLITTPESLSLLLCHERAHELFAPLRCVIVDEWHELLGTKRGTQVELALARLRRFAPGMRTWALSATLANLDEAARAAVGPNATPSFVSAGLERPVHMETLLPDSVDAFPWAGHLGMTMLRKVSDWLDPAHPTLLFTNTRSQAERWYEGLRFLRPEWEGVLALHHGSIDRDSREAVERGLKDGSVRLVVCTSSLDLGVDFGPVERVVQIGSPKGISRTLQRAGRSAHRPGATAHLLFIPTHALELVEMAAARDALAHREVEPRAPLRQPLDVLAQHLVTCALGGGFVREALLSEVRDTLAYCDLSEEDFDRALLLVTEGGPTLRAYPQFHRVRRVEDRYVVADARVARLHRLNVGTIASDATVELRYWTGGRIGTVEESFVSRLRPGDTFLFAGKRLEFSRMKDLTAYVKAAKQRASATPRWSGGRLPLSGSLAAAVRRTFHAVREGHLDAAELRAARPVLDAQARLSRVPAQDACLVELCRTREGHHLFLYPFEGRLVHEGLAALLALRLTRLQKATFSLAVNDYGLELLSPSPFPFEEALRPALFTRERLVEDILESVNLGELARRQFRDVARVAGLVMPGLPGARKSTRQIQASTGLLYDVFARYEPDHMLLAQARREVLEQHFEQVRLVSTLERLERTPLECVHVPRPTPLAFPLVVERMGATLSNETLLDRVQRMKEKWLREDSLSA
>NZ_CP022098.1|WP_095984914.1|2259003_2260599_-|ATP-dependent-DNA-ligase
MRRLVDLYEALDSTTSTNAKVDALVDYFRRTPPEDAAWGLFFLTGRRIKRLVPSKALKQWARELSDTPEWLFDEAYASVGDLAEIIALLLDSAEQPQVTEELPLSRWMEERILPLGGLALPEQRERITGWWHTLPRRELFVFNKMLTGELRVGVSDTLVVRALAQYAGLPPAAVSHRLMGTWAPSRAFFEQLIAPDVSDGDRSRPYPFYLASPLEQPVEGLGDRSEWMVEWKWDGIRGQLIHRQGGIYLWSRGEELVTERYPEIAKAAASLPPGTVLDGEILAYEDGKPLPFARLQRRIGRQKLTAKVLAEAPAVFMAYDLLEEKGEDLRPLPLRERRARLEALLRDKPRFPISPRVPADTWEELAQARRESRERNVEGFMIKRLESPYQHGRKRGDWWKWKIDPFTVDAVLLYAHPGHGKRAALYTDYTFAVWKGEELLPVAKAYSGLTDEEISRLDRWIRAHTKEKFGPVRSVEPAQVFELHFEGIAASPRHKSGVALRFPRIARWRSDKAPKDADSLDQLKELIHAPT
>NZ_CP022098.1|WP_095991899.1|2260604_2261624_-|ligase-associated-DNA-damage-response-exonuclease
MARSATRQPLVTVTPEGLYCPQGDFHIDAWRPVSRTLITHAHGDHARWGSQQYLGTRPSRGLLRKRLGADADITTLDYGECLTLGGVTVSFHPAGHVLGSAQIRLEYKDEVWVVSGDYKRDADPTCQPFEVVPCDTFITEATFGLPIYRWDDTRRVAEEVLHWWDANREAGRASVLFCYALGKAQRLLAELARVTDREVFVHGATHALVELYREASVPMLPTRPVSEAEKGTSYAGALVLAPPSSAGSTWMRRFGEHETGFASGWMRVRGNRRRRGYDRGFVLSDHADWPGLLRTAKETGASRVLATHGSSDTLSRYLRENLGIDAAPLATPFEGEAED
>NZ_CP022098.1|WP_095984915.1|2261723_2261975_-|hypothetical-protein
MDEKEYLNRRMGIPLDPAKQKDPEEHGDRVPAEGRAEHLNDITEQNGGQRSEVGPPWHDTSLERGLSDEFDKHGGRGKPKKKR
>NZ_CP022098.1|WP_095984916.1|2262121_2262889_-|ROK-family-protein
MSQKAPQPSPRKKTVRETHATGPRTLAIDIGGSGLKALVLGPEGTALDERRRVKTPKPATPKAVLRALEKLIKPLGAFERVSVGFPGVVEEGVTKSAHNLHPDWTGFNLAEALHQLTKRPVRVLNDAGVQGFGVIEGKGLEMVLTLGTGMGCALYIDGKYVPNLELAHHPFHGGKTYEDYVGQAALERVGKKKWNKHVERVLQQIQPIWNPRQIYVGGGNARLLDIKLPPNVKITENIAGLLGGFALWKDEPRQR
>NZ_CP022098.1|WP_095984917.1|2263138_2263636_+|folate-biosynthesis-protein
MARTTTIELHKEDMKFAAGHFTIFSATHRENMHGHNFAVFVSLTGEVLDNGMLADYDIFKRMALEQCRAWNETFMLPAHSRHLQVERDARGDVIARFNGEELRFLSRDVTILPVENVSLEELSRLFGEKLVGDGELMRTSRISRVVVKCSSEPGQNCSWEWNSHG
>NZ_CP022098.1|WP_095984918.1|2263628_2264336_+|SDR-family-oxidoreductase
MADWAIITGASRGIGRAAAVRFLQAGWRVMNVSRRPCPEPGVVNVLADLSTPGWEATFTPALSTALGSSPGRVCLVHNAALYGHDDALSLDAEHLRRVLEVNVVAPATLNRLVRGYLTDGSSILYVGSTLSEKAVRGAASYVTSKHALAGLMRSTCQDLVGTRVHTVCVCPGFTDTEMMRENVGDSEAARANTAARMTYGRLIAPEEIADVLLRCAEMPVFNGAVLHANLGQIET

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_10

2949490-2949630

Orphan

Consensus_repeat	Method
CAGGTTTCAAAGGACTCGTTCTGACACCTCGTTGCCTACGAGTCGTCTGACACC	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NZ_CP022098_10

>merge|NZ_CP022098|10|2949490-2949630|CRISPRCasFinder
CAGGTTTCAAAGGACTCGTTCTGACACCTCGTTGCCTACGAGTCGTCTGACACCCTTCCTGGTCCGTGGTGTCCCAGTGGAGCTCCACAGGTTTCAAAGGACTCGTTCTGACACCTCGTCGCCTACGAGTCGTCTGACACC

>NZ_CP022098|10|10|2949490-2949630|CRISPRCasFinder
CAGGTTTCAAAGGACTCGTTCTGACACCTCGTTGCCTACGAGTCGTCTGACACC	CTTCCTGGTCCGTGGTGTCCCAGTGGAGCTCCA
CAGGTTTCAAAGGACTCGTTCTGACACCTCGTCGCCTACGAGTCGTCTGACACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_095985379.1\|2949771_2950443_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380667
NZ_CP022098.1\|WP_095985378.1\|2949021_2949201_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095985377.1\|2948537_2949002_+\|polyketide-cyclase	unknown	unknown	gnl\|CDD\|176902
NZ_CP022098.1\|WP_095985384.1\|2955061_2956291_+\|SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|237857
NZ_CP022098.1\|WP_095985380.1\|2950445_2950925_+\|SMI1/KNR4-family-protein	unknown	unknown	gnl\|CDD\|378155
NZ_CP022098.1\|WP_095985373.1\|2945196_2946294_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225814
NZ_CP022098.1\|WP_157758399.1\|2947114_2947483_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095985383.1\|2954593_2954743_-\|addiction-module-protein	unknown	unknown	gnl\|CDD\|131625
NZ_CP022098.1\|WP_095985381.1\|2953396_2953861_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_157758398.1\|2946290_2947028_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225818
NZ_CP022098.1\|WP_095985372.1\|2943171_2944185_+\|DUF1028-domain-containing-protein	unknown	unknown	gnl\|CDD\|377639
NZ_CP022098.1\|WP_095985371.1\|2940442_2942893_-\|S9-family-peptidase	unknown	unknown	gnl\|CDD\|224423
NZ_CP022098.1\|WP_095991962.1\|2948218_2948551_+\|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|378968
NZ_CP022098.1\|WP_095985387.1\|2958441_2959908_+\|UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl--meso-diaminopimelate-ligase	unknown	unknown	gnl\|CDD\|223844
NZ_CP022098.1\|WP_095985376.1\|2947512_2948058_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095985385.1\|2956377_2957277_+\|LD-carboxypeptidase	unknown	unknown	gnl\|CDD\|132882
NZ_CP022098.1\|WP_095985388.1\|2959911_2960448_+\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
NZ_CP022098.1\|WP_095985386.1\|2957273_2958449_+\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NZ_CP022098.1\|WP_095985382.1\|2953900_2954131_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP022098.1\|WP_095985370.1\|2939686_2940205_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095985379.1\|2949771_2950443_+\|hypothetical-protein	gnl\|CDD\|380667	cd20014, PBP1_RPA0668_benzoate-like, type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the active transport of lignin-derived benzoate derivative compounds, and its close homologs. This group includes RPA0668 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0668 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).	0.00149686
NZ_CP022098.1\|WP_095985382.1\|2953900_2954131_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	5.04232e-11
NZ_CP022098.1\|WP_095985377.1\|2948537_2949002_+\|polyketide-cyclase	gnl\|CDD\|176902	cd08893, SRPBCC_CalC_Aha1-like_GntR-HTH, Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins; some contain an N-terminal GntR family winged HTH DNA-binding domain. SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of a functionally uncharacterized subgroup of CalC- and Aha1-like proteins. This group shows similarity to the SRPBCC domains of Micromonospora echinospora CalC (a protein which confers resistance to enediynes) and human Aha1 (one of several co-chaperones which regulate the dimeric chaperone Hsp90), and belongs to the SRPBCC domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. Some proteins in this subgroup contain an N-terminal winged helix-turn-helix DNA-binding domain found in the GntR family of proteins which include bacterial transcriptional regulators and their putative homologs from eukaryota and archaea.	6.87127e-60
NZ_CP022098.1\|WP_095985384.1\|2955061_2956291_+\|SAM-dependent-methyltransferase	gnl\|CDD\|237857	PRK14902, PRK14902, 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB.	2.00771e-92
NZ_CP022098.1\|WP_095985380.1\|2950445_2950925_+\|SMI1/KNR4-family-protein	gnl\|CDD\|378155	pfam09346, SMI1_KNR4, SMI1 / KNR4 family (SUKH-1). Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Genome contextual information showed that SMI1 are primary immunity proteins in bacterial toxin systems.	3.43505e-17
NZ_CP022098.1\|WP_095985373.1\|2945196_2946294_+\|hypothetical-protein	gnl\|CDD\|225814	COG3275, LytS, Putative regulator of cell autolysis [Signal transduction mechanisms].	6.60793e-47
NZ_CP022098.1\|WP_095985383.1\|2954593_2954743_-\|addiction-module-protein	gnl\|CDD\|131625	TIGR02574, hypothetical_protein, putative addiction module component, TIGR02574 family. Members of this family are bacterial proteins, typically are about 75 amino acids long, always found as part of a pair (at least) of two small genes. The other in the pair always belongs to a subfamily of the larger family pfam05016 (although not necessarily scoring above the designated cutoff), which contains plasmid stabilization proteins. It is likely that this protein and its pfam05016 member partner comprise some form of addiction module, although these gene pairs usually are found on the bacterial main chromosome. [Mobile and extrachromosomal element functions, Other].	0.000778573
NZ_CP022098.1\|WP_157758398.1\|2946290_2947028_+\|response-regulator-transcription-factor	gnl\|CDD\|225818	COG3279, LytT, Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms].	4.06488e-52
NZ_CP022098.1\|WP_095985372.1\|2943171_2944185_+\|DUF1028-domain-containing-protein	gnl\|CDD\|377639	pfam06267, DUF1028, Family of unknown function (DUF1028). Family of bacterial and archaeal proteins with unknown function. Some members are associated with a C-terminal peptidoglycan binding domain. So perhaps this could be an enzyme involved in peptidoglycan metabolism.	1.23473e-45
NZ_CP022098.1\|WP_095985371.1\|2940442_2942893_-\|S9-family-peptidase	gnl\|CDD\|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	1.4793e-53
NZ_CP022098.1\|WP_095991962.1\|2948218_2948551_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|378968	pfam12840, HTH_20, Helix-turn-helix domain. This domain represents a DNA-binding Helix-turn-helix domain found in transcriptional regulatory proteins.	1.37176e-15
NZ_CP022098.1\|WP_095985385.1\|2956377_2957277_+\|LD-carboxypeptidase	gnl\|CDD\|132882	cd07025, Peptidase_S66, LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein. LD-carboxypeptidase (Muramoyltetrapeptide carboxypeptidase; EC 3.4.17.13; Merops family S66; initially described as Carboxypeptidase II) family also includes the microcin c7 self-immunity protein (MccF) as well as uncharacterized proteins including hypothetical proteins. LD-carboxypeptidase hydrolyzes the amide bond that links the dibasic amino acids to C-terminal D-amino acids. The physiological substrates of LD-carboxypeptidase are tetrapeptide fragments (such as UDP-MurNAc-tetrapeptides) that are produced when bacterial cell walls are degraded; they contain an L-configured residue (L-lysine or meso-diaminopimelic acid residue) as the penultimate residue and D-alanine as the ultimate residue. A possible role of LD-carboxypeptidase is in peptidoglycan recycling whereby the resulting tripeptide (precursor for murein synthesis) can be reconverted into peptidoglycan by attachment of preformed D-Ala-D-Ala dipeptides. Some enzymes possessing LD-carboxypeptidase activity also act as LD-transpeptidase by replacing the terminal D-Ala with another D-amino acid. MccF contributes to self-immunity towards microcin C7 (MccC7), a ribosomally encoded peptide antibiotic that contains a phosphoramidate linkage to adenosine monophosphate at its C-terminus. Its possible biological role is to defend producer cells against exogenous microcin from re-entering after having been exported. It is suggested that MccF is involved in microcin degradation or sequestration in the periplasm.	9.14052e-100
NZ_CP022098.1\|WP_095985388.1\|2959911_2960448_+\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.04848e-37
NZ_CP022098.1\|WP_095985386.1\|2957273_2958449_+\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	1.48795e-41
NZ_CP022098.1\|WP_095985387.1\|2958441_2959908_+\|UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl--meso-diaminopimelate-ligase	gnl\|CDD\|223844	COG0773, MurC, UDP-N-acetylmuramate-alanine ligase [Cell envelope biogenesis, outer membrane].	2.25972e-147

>NZ_CP022098.1|WP_095985378.1|2949021_2949201_-|hypothetical-protein
MRARDAAGNVDETPAARTFRVTGADLALLGSGCSTTGADASLVLLGLGTFTALARRHRG
>NZ_CP022098.1|WP_095985377.1|2948537_2949002_+|polyketide-cyclase
MTTRKPQFVYVTYIQTTPEKVWAALQDPELTRQYWGMHKNVSDWKAGSRWAHQDYETNEVRVTGQVLESEPPKKLVLSWGSPEGRPGAEPPSKVTFLLEPFMGAVRLTVLHDELVEGGETMKGISQGWPAILSSLKSLLETGQPLVMTTKRWGR
>NZ_CP022098.1|WP_095991962.1|2948218_2948551_+|helix-turn-helix-transcriptional-regulator
MGEMDMDLVFKALADKSRRQLLDLLHQENGRTLGELCEHLDMSRQAVTKHLAVLEEANLVAVVWRGREKLHYLNPVPLHDIYERWIGKFERQRLRALHELKKGLEEDDDP
>NZ_CP022098.1|WP_095985376.1|2947512_2948058_+|hypothetical-protein
MKRLLAAVLSSLVVTACGSETAAPPPTHEPETDPCQRGVLEPDFQASSALQGPGVDANGQLSPGSYIISSTYLRMRSTVEAQTEFDAAVVGLNETLPTQPGLMAVQFGGSESCNTKRTLTVWKDEASMYQFVASPAHRRAMLKVGVMSRGGGIVTSWAGDERGAIWSEAIEHLSRETRPTY
>NZ_CP022098.1|WP_157758399.1|2947114_2947483_+|hypothetical-protein
MRRTLLILSMLSLLALGGVGWVQTRTPGDNPLSRHALAPSDQMRLTGFVEERLPAGSYLYLRVRAPDGSRHWVATLSTAASRESAVQVQVFARADDFHSRRLGRDFSPLLFGSVQAAPSSSR
>NZ_CP022098.1|WP_157758398.1|2946290_2947028_+|response-regulator-transcription-factor
MRILIVDDEEPARRRLSRLLSGLPDVEVVGDAGDGEEALRRVEELRPDLLLLDVRMPGMDGLALAQRYRELPPLIFVTAHDDYAVRAFEAHAVDYLLKPVRPERLADALERARGRLLAKQAAVARVLEAVAPVDSSCRIVTVSQGVFHFFDARSISRFWSSDKYTLFLADQREQCTEESLTQLEERLRSHGFLRVHRGELIQLTHVKAVHSRNGEHEVELQDGQLARVSRRSASTLKAALGMKAR
>NZ_CP022098.1|WP_095985373.1|2945196_2946294_+|hypothetical-protein
MRASSDSTLGRIEDQDDPGPLLPLEMIWLYFVAPLATAPLLDKDFFTLSLAKSLQHVATGYPIFFTLALTLHSLYIWVMPGLVRRLRSPLAQGVLHVAVGSGVPLVMVILVIHPLKVRLGVGLRYSMAQDLLVATLVSWMFLFPGLLVQRLRNTAARIERRALLAQRAALEAQLSALQARIQPHFFFNSLNTVASLISENPELAERTLERLAELFRYALDSGKSRFVSLERELDMTRDYLAIQTARFGARLRTHLAVDEHVSGIPLPPLVLQPLVENAILHGMDRREGVSVRVLVRREETWLHLEVIDDGPGPGASEHQGAQTGVKDLRERLRLLYGEQGTLTLEPLPGGGCRARITLPSGGPPR
>NZ_CP022098.1|WP_095985372.1|2943171_2944185_+|DUF1028-domain-containing-protein
MTSFKRGLLVVSSLMLASTSALAAAPAPTINPRLLGTRAIVACDPVEKSCGVASISFPAGISGLVPYGRPDVAVATMFYPSVDDAEAILARTAAGDTAQGAVDFVFSVDPYANYRQLAAVKLNPDGTVTVGQRTGEQNTEHRCAVKGATFVVQANNQTTPAMCGAMAQGFQEAKGSLPQRLLAALKAGALVGGDRNGERSGVIRVWSAENEAAFYTHVLVDAVVHGSSNALKELDVEMNRYQASVAAPYEADLIPLDSETSKYVKLVLSKLGYYNSRVDTSWSDADEQALHDFNWNNLFFLKPTVVVNGVRKIDRPLVRFLRNADLGALQPATTATP
>NZ_CP022098.1|WP_095985371.1|2940442_2942893_-|S9-family-peptidase
MTPATLPVLAAILTATASTLAVESGYRTPPEPIASILAASPSPEVLVSPQHQSLALLGYESMPSIAQLSRPILRLAGYRIDPATTGQNEAQVWWLNALTLQDLATGRQSTVRLPEGTRYSQLRWSPDGRRLALVLERPKELELWVVEQDGSARRLAGAVNAAFGTAYAWLPDGTGFIVRQVRADRGAPPVADGTPTGPIIEENSGQTRPARTNPDALRGPADEALFEYYFTGQLVRVALDGSAPRPIGTPGLIARFSVSPDSRYLLTETLKRPFSYLLPADNFPREIAVATLDGQRVRMVVDRPLADEVPIDMGSVVQGPREVDWRADAPATLAWAEALDGGNPKADVPFHDSLWMQAAPFKGAPVKLADLKERFHKVYWGRADHALVFERKWKTRTERRSVVNPSRPGTARLLLERNHQDQYGDPGAPLLETNAAGKPAMRYTADGRAFLVLGPGATKAGYFPFVNRQEVASGQVKRLWTAQAPYYERVEAVLDADGDRLLTQRQSATEVPNYWLRTVKDGKSRAITSFKDPAPVFAGVTQKQITYARADGLPLSGMLYLPAGYDPKRDGPLPTLLWAYPAEYTDASVAGQTVDMSNLFTRPEGFSHLFMLTQGYAVLDNPAMPIVGANGAEPNDTYVEQLRANAEAAVEALVKLGVGDRDRMAVGGHSYGAFMTANLLAHTDLFRAGVARSGAYNRTLTPFGFQFEERTYWKAPEIYTRMSPFTYADRIREPLLLIHGGADNNPGTFPIQSERFYAAIKGNGGTARYVVLPNEAHGYAARESIGHVNWETVKWLDRYVKNAPPRAPATAADTVR
>NZ_CP022098.1|WP_095985370.1|2939686_2940205_+|hypothetical-protein
MPILTKPRDPRFITVRRGGTLSDANHRLLAIWAAACAEHVLHLFEEAQPEDERPRQSIELARAWTRGEITMRQAHKAAFVANAAARELSGAAKLAAYAAGQAVAVAHVAAHELGAAAYAIRAVQAAAPESEREQAGRRECQWQREQLPDEIRELVLDDQRLRNHVCWFVFDC
>NZ_CP022098.1|WP_095985379.1|2949771_2950443_+|hypothetical-protein
MKLAGAVVLLVFLTGCATTQRSDGPGTGGSGPSPSPGAKPAVKKELPWLNVPGGRMKTTLFYGPWQCRREFMNGCQRECASEGYKLMGCMWLADFKFDWEGRLVALPVPVKGGSRYGIYHCCCDYPELSPEDNAAQRKAWSRFRTSFRKAWSEKFGQWPEQGGVSWPGHHIRDLWHAGNPVDPNNVFPAQPDVHEVYNDQYPACYGGKSPWNTVGPNLPYTDN
>NZ_CP022098.1|WP_095985380.1|2950445_2950925_+|SMI1/KNR4-family-protein
MATSMSRLLEEVSRDHFPYPPATPEEIEEFERRVGWRLDADLRAFYLHCNGAELIERLPDTPYRILPLSQVVRARVAIFGKKNDDDAHGPASMWVICDIQDGNYVLVDVARQENDHYPLTDGYHEAWPNPKYCGPVASSFSEFLEQVLRTQRGLYWLGE
>NZ_CP022098.1|WP_095985381.1|2953396_2953861_+|hypothetical-protein
MTAKDDASPEKDASTGPKHEPSEERCFRQVHPQFFQKGRLTEMAFRLKDHEHGLSISLSSKTSAEKAFAFYTKPKEQGGKGLPACGTWAVTTAECHRETCDVYEDPTEIDPAHGSIDMRHLKADKSRRKEVQTNLRIYAEERGCVFSPTKEEGE
>NZ_CP022098.1|WP_095985382.1|2953900_2954131_-|tyrosine-type-recombinase/integrase
MSTNFVDTPLAIKGACETAGIPPLTPGRFQHSVATWAIEKGADPASVAAFLNHKSPSTTRRFYATHAVPTKVPTLH
>NZ_CP022098.1|WP_095985383.1|2954593_2954743_-|addiction-module-protein
MGRQATHPEQVETAPEQLPELERRLAELGADPVGGESWDVVKTRILESL
>NZ_CP022098.1|WP_095985384.1|2955061_2956291_+|SAM-dependent-methyltransferase
MPWLALEGLASLVTASLSLVLSGQPVERALDRTLRAHRHLSRDQRQVLAEALFNVSLWRRRLGFHLGTPVDPPASSLLYAFLHLLAGLPSDVAARLAEVGTPPPPLVPDVPPSLALRCSLPDWLADHFAREWGPAAEDFCAHLNVPGPVTLRVNRLRTDRDSLQARLRSEGVETQPGLLSPLALHVVGPRPNLYGLASLREGLFEVQDEGSQLLGLLVEPHPGETVLDLCAGAGGKTLQLGAAMENQGRLLAYDPDAGRLDRLLQRCARAGVSNVHVLRAPPERLLVDRVLVDAPCSELGPLRRGPDLRFRLAPSSLSELPRVQREILDRTRSLVRPGGRLVYATCTVNRAENEDLVLGFLRDAPEFRLVPAEGSGALGSCARDGFWVCAPHLHGCDAFFAAVLERTEG
>NZ_CP022098.1|WP_095985385.1|2956377_2957277_+|LD-carboxypeptidase
MRWLKPLPLRPRDTVQVVAPAGPFDVQAFEKGLEVLGQRYTPTYRPDLYDAWRYLAGSDARRAEELSAALSDTSSRAIFCARGGYGSMRLLPSLSFKDLAPSALVGFSDMTSLHAVLQASGRVSIHGPVVTHLGIQPPAVQDYLFRLLESPEPPPPLQGTTLYVPGVVEGPLLGGNLSVFSRLLGTPYLPPLDGAILLLEDVGEKPYRLDRMWTHLRLAGVFDRVRGIVLGQFTDCENKDSPYGSADVLRSLAEETGLPCAAGFPIGHDTPNYPVALGTHVRLDAGAALLTFLEGAVQA
>NZ_CP022098.1|WP_095985386.1|2957273_2958449_+|serine-hydrolase
MSSHPIAQLQQVLDEAVTLGIFPSAQAVVLHRGVQVFGGVAGPVTGDTRFDLASLTKVLNTTALFLRLWTEGKVGPETPVARFFPGSPVGDAGATVADLLYHRSGLPPFVPFFAEALTSTPELLDPACSSTTRARVRDEVIQAAARTPLAAPWRTRTAYSDVGFILLGEILARVGGAPLDILFSRHVAGPLGLGARYHRLTDFPTDGLVAPTGATRPREPAPGQETMWGELPSRPSVLGEVDDDNAWVLDGVSGHAGLFGTAVDVARFGQAILAGCAGDAAIAPGPLWFRALATDPLLPGSTRSMGFDSPSEGLSSAGHFIGDTPPGAVGHLGFTGTSLWVDLRRSLVVALVTNRVAHGRKEVRIRDFRPIFHDLVVDSLGLDDLTPKAHG
>NZ_CP022098.1|WP_095985387.1|2958441_2959908_+|UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl--meso-diaminopimelate-ligase
MADDNGNVLDTLSPGAVRRIHLIGVAGTGMGSFAGMLKAAGYDVTGSDENVYPPMSDMLRAWGIQALTPYKPENLDVVRPDLVIVGNVIRRVNPEATAVRERRLPQMSFPAALGSLFLEHAHSVVVAGTHGKTTTSSLMAHVLVEAGRDPSFLVGGVTQNYAGNYRVGKGAHFVVEGDEYDTVYWDKGSKFLHYRPKTAILTSVEFDHADIFRDLPHYESTFDKFVRLIPKDGRLVVCAAYPNAVKLARACPGEVITYVAREGAEADYTPRNVRFGPEGARFEVVERGSVLGTALVTLSGMHNVENTLSVIAAARGLGLSFEEICRGLATFQGVKRRQEVRAEVGGILVVDDFAHHPTAVRETIAAIRHRYPERRLWAIFEPRSNTSRRNIHQEDYAHAFTGAARASLKVPERHDKVPVDQELDVPRVIEALKAQGIAADSTVDVPSLVERVARESQPGDVLLVMSNGSFGGFIDKLLAALRARMGEG
>NZ_CP022098.1|WP_095985388.1|2959911_2960448_+|TlpA-family-protein-disulfide-reductase
MRSIRLLLTSLALSGCVSAMPPLTGSALRTSQAGLGGGEPLEFTVKRHPGGEPYSLSEDRGSVVLIDVWATWCEPCRDALPLYQELAKHYGARGLKVYALNVDEDVRAVPPFLAETKVALPVLLDAQAAVADKVLRVRGLPTMLLVDRKGHVRYMHEGFAEEYLMKYQNEIEELLSEQ

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_11

3030314-3030463

Orphan

Consensus_repeat	Method
TGTGCTTCCAGCTCCGCGATGCGG	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP022098_11

>merge|NZ_CP022098|11|3030314-3030463|CRISPRCasFinder
TGCGCCTCCAACTCCGCCACTCGGCGGGTGAGCGCCTTCACCTGTGCTTCCAGCTCCGCGATGCGGGCATCCCGCGCGGCCACCTGTGCTTCCAGCTCCGCGATGCGGGCATCCCGCGCGGCCACTTGTGCTTCCAGCTCCGCGATGCGG

>NZ_CP022098|11|11|3030314-3030463|CRISPRCasFinder
TGCGCCTCCAACTCCGCCACTCGG	CGGGTGAGCGCCTTCACC
TGTGCTTCCAGCTCCGCGATGCGG	GCATCCCGCGCGGCCACC
TGTGCTTCCAGCTCCGCGATGCGG	GCATCCCGCGCGGCCACT
TGTGCTTCCAGCTCCGCGATGCGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_095985426.1\|3022546_3024454_-\|response-regulator	unknown	unknown	gnl\|CDD\|236901
NZ_CP022098.1\|WP_095985424.1\|3018637_3019951_+\|M18-family-aminopeptidase	unknown	unknown	gnl\|CDD\|235073
NZ_CP022098.1\|WP_095985423.1\|3017167_3018571_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|350609
NZ_CP022098.1\|WP_157759138.1\|3040867_3041389_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|224511
NZ_CP022098.1\|WP_157758404.1\|3025560_3025803_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095985438.1\|3042734_3043913_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095985425.1\|3020929_3022540_+\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|143636
NZ_CP022098.1\|WP_095985437.1\|3041508_3042564_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|184918
NZ_CP022098.1\|WP_095985427.1\|3024724_3025513_-\|DUSAM-domain-containing-protein	unknown	unknown	gnl\|CDD\|370553
NZ_CP022098.1\|WP_095985439.1\|3043922_3044561_-\|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|238870
NZ_CP022098.1\|WP_095985434.1\|3033395_3034586_-\|cytochrome-P450	unknown	unknown	gnl\|CDD\|225035
NZ_CP022098.1\|WP_157758405.1\|3026137_3027034_+\|DUF2381-family-protein	unknown	unknown	gnl\|CDD\|370554
NZ_CP022098.1\|WP_095985430.1\|3027719_3028508_-\|DUSAM-domain-containing-protein	unknown	unknown	gnl\|CDD\|370553
NZ_CP022098.1\|WP_095991968.1\|3019967_3020648_-\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
NZ_CP022098.1\|WP_095985436.1\|3040055_3040871_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|276809
NZ_CP022098.1\|WP_095985435.1\|3034727_3040028_+\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|223256
NZ_CP022098.1\|WP_095985432.1\|3031741_3032230_+\|serine/threonine-protein-kinase	unknown	unknown	unknown
NZ_CP022098.1\|WP_095985429.1\|3027036_3027525_+\|serine/threonine-protein-kinase	unknown	unknown	unknown
NZ_CP022098.1\|WP_095985431.1\|3030782_3031730_+\|DUF2381-family-protein	unknown	unknown	gnl\|CDD\|370554
NZ_CP022098.1\|WP_095985433.1\|3032295_3033282_-\|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|379142

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095985426.1\|3022546_3024454_-\|response-regulator	gnl\|CDD\|236901	PRK11360, PRK11360, two-component system sensor histidine kinase AtoS.	1.27e-54
NZ_CP022098.1\|WP_095985424.1\|3018637_3019951_+\|M18-family-aminopeptidase	gnl\|CDD\|235073	PRK02813, PRK02813, putative aminopeptidase 2; Provisional.	0
NZ_CP022098.1\|WP_095985423.1\|3017167_3018571_+\|hypothetical-protein	gnl\|CDD\|350609	cd14727, ChanN-like, ChaN is an iron-regulated, heme-binding protein. This family represents a domain found in ChaN, a heme-binding/iron-regulated lipoprotein from Campylobacter jejuni. ChaN, possibly involved in the uptake of heme-iron, contains a pair of cofacial heme groups situated between two ChaN monomers. A single tyrosine residue contacts the heme-bound iron atom while the heme-binding regions of each monomer also have contacts to the heme in the complementary monomer. ChaN presumably associates with an outer membrane-associated receptor, ChaR. Campylobacter jejuni is an important cause of food-borne illness, and is dependent on iron uptake from the host. ChaN like proteins are related to the Tiki/TraB like family of proteases. Proteins containing this domain also include protein reticulata-related from Arabidopsis which may play a role in leaf development.	0.000543374
NZ_CP022098.1\|WP_095985433.1\|3032295_3033282_-\|trypsin-like-peptidase-domain-containing-protein	gnl\|CDD\|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	3.30137e-14
NZ_CP022098.1\|WP_095985425.1\|3020929_3022540_+\|GAF-domain-containing-protein	gnl\|CDD\|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	2.89591e-69
NZ_CP022098.1\|WP_095985437.1\|3041508_3042564_-\|hypothetical-protein	gnl\|CDD\|184918	PRK14954, PRK14954, DNA polymerase III subunits gamma and tau; Provisional.	0.00100455
NZ_CP022098.1\|WP_095985427.1\|3024724_3025513_-\|DUSAM-domain-containing-protein	gnl\|CDD\|370553	pfam09543, DUF2379, Protein of unknown function (DUF2379). This family consists of at least 7 paralogs in Myxococcus xanthus and 6 in Stigmatella aurantiaca, both members of the Deltaproteobacteria. The function is unknown.	9.28404e-45
NZ_CP022098.1\|WP_095985439.1\|3043922_3044561_-\|SGNH/GDSL-hydrolase-family-protein	gnl\|CDD\|238870	cd01832, SGNH_hydrolase_like_1, Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid. Myxobacterial members of this subfamily have been reported to be involved in adventurous gliding motility.	2.85734e-32
NZ_CP022098.1\|WP_095985434.1\|3033395_3034586_-\|cytochrome-P450	gnl\|CDD\|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	2.57332e-91
NZ_CP022098.1\|WP_157758405.1\|3026137_3027034_+\|DUF2381-family-protein	gnl\|CDD\|370554	pfam09544, DUF2381, Protein of unknown function (DUF2381). This family consists of at least 8 paralogs in Myxococcus xanthus, a member of the Deltaproteobacteria. The function is unknown.	1.00048e-42
NZ_CP022098.1\|WP_095985430.1\|3027719_3028508_-\|DUSAM-domain-containing-protein	gnl\|CDD\|370553	pfam09543, DUF2379, Protein of unknown function (DUF2379). This family consists of at least 7 paralogs in Myxococcus xanthus and 6 in Stigmatella aurantiaca, both members of the Deltaproteobacteria. The function is unknown.	4.7469e-40
NZ_CP022098.1\|WP_095991968.1\|3019967_3020648_-\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	9.57898e-45
NZ_CP022098.1\|WP_095985436.1\|3040055_3040871_-\|hypothetical-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	3.52618e-05
NZ_CP022098.1\|WP_095985435.1\|3034727_3040028_+\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|223256	COG0178, UvrA, Excinuclease ATPase subunit [DNA replication, recombination, and repair].	0
NZ_CP022098.1\|WP_157759138.1\|3040867_3041389_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	4.36854e-26
NZ_CP022098.1\|WP_095985431.1\|3030782_3031730_+\|DUF2381-family-protein	gnl\|CDD\|370554	pfam09544, DUF2381, Protein of unknown function (DUF2381). This family consists of at least 8 paralogs in Myxococcus xanthus, a member of the Deltaproteobacteria. The function is unknown.	3.04969e-35

>NZ_CP022098.1|WP_095985430.1|3027719_3028508_-|DUSAM-domain-containing-protein
MSDEINWDRIRDLAQRVLEHSETLELSEDTRALLSKSAREVAISAQEAEDALRDLPTATTLLREIRQRIRDGSHRLSRAEDRVEEFQEKGDFNGAVHVIRDVLAVEVVPLYRRHAEILLDELTGLANVFATGRLNPNLHDRQQLAALSQRIQQGHALELTDDLRALLRQTAPTAAIGEAETEESLKSPDGAEALMGMILSRFRKAQSRFLRSMYRMTSLRDSGDIEGARQQMRDVLAVEIVPQYRRMAEEQLRGLDSPPPES
>NZ_CP022098.1|WP_095985429.1|3027036_3027525_+|serine/threonine-protein-kinase
MPVKKPLALPTVFLLPLIAACLPAGVSLRSDGSPGPEKCSEKALEVMRILRMRVGDAADAHLDANQIDASPVIVYDGPLESYLTESLGTLEPGTRLYGQAWTGGFQVVVRYYEAHPPDGDKVPICAVARLGRGQMRKKPESKPGSALLEHGAVSVFVVDSFR
>NZ_CP022098.1|WP_157758405.1|3026137_3027034_+|DUF2381-family-protein
MAKEREPVSRNLYLSNSPRDEVRPVYVAGEMVTVLRFQQPCTEAGTKMLGWEGRFEPVVCVDKRVLIEPHQDLKPEDRFLLLVTLADGKELPFTVTAREERFDHQVSVFLDLETPEAARRRLADAYVRERTLEEENERLRKEQASTRHAYASLLASGEAKNTPFRRESKWRVELGGAVVDIYIYSARKMQKAAVLFHVTNSQLDVPWRLKEVQLSAMLSRQSYEESVRTGEKKELALRTSRDEIQPGESGYIAVVADKSAFTSKDGPVHLVLELFRHDGLQQAVVFLDHRIVEEKETH
>NZ_CP022098.1|WP_157758404.1|3025560_3025803_+|hypothetical-protein
MLPFATAQAVVAIAHPAVVYAIVIVPDALLFPFGKGLVVGEVVNIGAGAHSPEHLINLGLRGSTSAYRVVWVFLDAADHR
>NZ_CP022098.1|WP_095985427.1|3024724_3025513_-|DUSAM-domain-containing-protein
MSDEINWDRIRDLAQRVLEHSETLELSEDTRALLIKSAREVAISEQDAEDALRSLPTATTLLKEIRHRIGEGSRRLSRARNRAYELRDAGDLDGARQLMHDVLAVEVVPLYREQAETLLDQFTGLANVFATGRLNPDLPDRPQLAALSQRVQQGHALELTDDLRALLRQTAPTAAIGEAETEESLKSPDGAEALMGMILSRFRDAQSRFLRSMYRMTSLRDSGDIEGARQQMRDVLAVEIVPRYREAAEEQLRGLDSPPPES
>NZ_CP022098.1|WP_095985426.1|3022546_3024454_-|response-regulator
MRALLVPSASIDLSSVELLVRQLGMTPTRRSDDEAAIAAFRQSPFPLVLLGMDDEGDRIVLVRALRASPSGAQAAILLVARPEQLEGLASMIDAGVDDFLLLPLNETAAMLRLQLAERRLAERPAPLPENFELDGLCAVLLRESPLATCITTREGNAFVEVNEAFTRLFGYSREEMLWRTARDLDLWESPIEQERLAARMREQGMVRGVESRVRTKSGELRDVLVYVGIAEYAGTPHIVTLFPDVTERKLMQARLQLADRMASVGTLAAGVAHEINNPLAYVLANLGYAHGELSRQLSRGAPGVLQPVSTALGEALHGAERVQTIVGDLKTFSRESTAEQFHAVNVRKVLDSTLNLAAAEIRHRAKLVKNYGEDVPPIHGNESRLGQVFLNLLVNAVQSLPSDGDAEQHEIRVTTRLDASGQVAVEIADTGAGIAPELMGRIFDPFFTTKPPGVGTGLGLSICHNLITAMGGELHVFSDLGRGTTFQVLMPSSREPIVPALLEPVPEYSGGPRGRVLVIDDEPLLCSALERILRPHHDVVFTTLAAEVLPRLEAGERFDLILCDLMMPRMNGMDFHAALHRLRPELTGRVIFLTGGAFTPQAKAFLERVPNRRVEKPFNARTLLEITREVLTSVG
>NZ_CP022098.1|WP_095985425.1|3020929_3022540_+|GAF-domain-containing-protein
MQLIVNPGLLDERVVDLPEGATTIGRTQESTLCVLHMSLSRRHARLERQGTRVLLTDLDSKNGTLVDEVRLEKFTPRELKEGESFRCGEVRFTLVSPVGSVPLAPTQVQPLNTRFSPAAMDELLERVPESSSGSALRVKRASHENRANEKLQVLLKVSQLLSSPGQIETLLERILDLVFQIMEVDRVAILLVDPSTGALRPRVARVSTGEAPAGAFYSQRIVDYVRTHSVAALFSDAWMDPRLNDAASVVLQSIRASMCAPLKPRDEVLGVLYVDNLSRADGFSQEDLEFLTAFANQAAIALDNSLLAQKLAEEAVMRNAYARFFPPATLKKLSMARGGPLETIETEVTVLFSDISGFTALSSSREPRQVVDLLNDYFPVMADIVFRHEGTLEKYIGDALMAVWGAPFAHPDDATRAVRAAVEMQRALAGLNARWRERGWPELRIHVGLNTGRVAAGNIGSEQYLQYATIGDATNVASRVCSVAAEGQIIMSQATFERWLERDWSVTPLPPTPVKGKPEPLTLYRVEWNVPPLEWS
>NZ_CP022098.1|WP_095991968.1|3019967_3020648_-|Crp/Fnr-family-transcriptional-regulator
MSYTELLSQVPLFSSLEPGDLEQLSARLRPRRLGAGEVLFHRGDMGTDLYIIHEGEVTIRLSAADGKEVTLALLGRGDAFGELSLLDDAPRSTDAVARKDTELLSLQREAFRQFLQERPQVMPKLLAELSQLVRRVTRAVHDASFLDARARLARVLLDLAQSRGRPGAQGVAITSRLTQSELANLCGLTRESTNRWLRFYAREGLLTYEDGVITLLDPEDLSLNAD
>NZ_CP022098.1|WP_095985424.1|3018637_3019951_+|M18-family-aminopeptidase
MTASATDAAAQDLLAFIDASPTPYHAVAEASRRLTAQGYRALDEREPWDLKPGDKFFVTRGDTSIAAFHLGQTPVDRAGFRLVGAHTDSPNLRVKPQPQAGRAGYHQLGVEVYGGVLFSTWMDRDLSLAGRVVTARDGKLAHHLVDFRRPLLRIPNLAIHLNRSVNTDGLKLNAQEHLVPVLALERSGAVDLKALLVEELARHSVQASAGDLLGYDLCLYDTQPSTRSGAFGEFLHAPRLDNLASSHAGLSALLALESPGAATRGVVLYDHEECGSVSAQGAASPFLKDLLERITHAHSDGRRDAFHRAMRHSFLVSADMAHAVHPNYASMHEPKHQPLLGGGPVIKSNVNQSYATDGETWAWFALCCREAGVVPQNFVTRTDLGCGSTIGPISAGELGIRTVDVGSPMLSMHSIREMAAAADVAAMISVLRQHYSR
>NZ_CP022098.1|WP_095985423.1|3017167_3018571_+|hypothetical-protein
MRRSVWGWLWLLVVVSGCTSRFVDFAPDEEAIYAQPIDEVWPQVRAYFRANGFAFREVPGGASLETEWREEFAGSRVSAYWHRYLVTARPEGPHRCKLVITRESRSVNKALKAPGSELLWVVDGRTNDNPSGIGSPMAAMLAQQQSDEAVVLVGESQQSARDLVLEWKVFRKISPVIAREKKTSSASPDVEVMKDAMVECGVPILGLGRLARAGNVVLLGEVHGTQQVPHFVAQSACQVATQAIPVTVGVEVPAGNQARLETFLASEGGEEDWAKLMESPFWRSPYPDGRNSEAVAYLLEALRKLRAQGMDVRLFAYDHPALEGEAREEAMARTVLEVAAASPGRALLVVSGNLHPRQVQGLPWNRDYQPMGLRVARERRDVHSLDVAYKSGTVWICAVGPEQKLDCGVKPARGQDNGDRYFVQLFNGLNDQGYHGIFYVGEVSASMPAVFQGMEPAGDVRATSSGR
>NZ_CP022098.1|WP_095985431.1|3030782_3031730_+|DUF2381-family-protein
MRNFLPPRSVLLLALMASVAMARERFPSVRSVYVRNDPQERAEQLFVTRDVTTVLRFQQPCTDAGTKILGWEGRFEPVVCAGKRVLIEPVQTLEPEDRFLLVVRLADGTEVPFTISGSSWKEGEWPDQQVNVFLEPDAPDALRKQLEEYKERERELWEQLRVESFTGSSENHTLAALLTQGAVRFTPFVARKAWIFKKEDSNIQATVLTDGKEKMAVLFRVTNRDPSTPWRLMDARLFVLPPGFQPPLFVGEGRPFALRTDKKVIPPGETGYVAVVADRSAFDSPQGPTKLFLGIFRHDGMMAAHVTLDRSLFKK
>NZ_CP022098.1|WP_095985432.1|3031741_3032230_+|serine/threonine-protein-kinase
MRSARALIRPSLLLFLAATGCPTAGVPLRPDGSPGPEKCSEEALNAMRILRLRPGDSAFVELDVNQTDTSPITLYDGPVESMLNEPLGPLEAPTRLYGRVWTGGPQVVVRYYEARPPHGDTIPICAVARLAHGQLKKLPESKPGMAVLEFSSSGVFVVDSFR
>NZ_CP022098.1|WP_095985433.1|3032295_3033282_-|trypsin-like-peptidase-domain-containing-protein
MPAVDTGLSAVRDAATSALITLDMPNRRGVGFVATPGGQLVTNLHMVAGCEDISALLADGRLLQVEQVIAFDEKHDLAVLQLPVSNVPALRLESGGLLPVEGDPVFILHPAPGTPPFLLETRVRSEQVLDESFTFLELEAILPEDVSGSPVLDATGAWIGVATCAFADGRPVTIVIPSRYVLPLLERTDALPLSTLGLARPAASRQRQIPTHSLSMLEGCAPDVLEEVAYTLLRAIQLGAPLYNRGDAAACHHLYAHTAERLIRERPDCPGIQDALRHGLERCTRLQGADACAWALRDTLDGLLGVIGRWLQAQSALAYRAAPKAYLQ
>NZ_CP022098.1|WP_095985434.1|3033395_3034586_-|cytochrome-P450
MSGRINLLAPEIRANPYPAYAELRRNAPVSQVDPGGLWAVSRQEDVMHVFKNPQLFSSQGFRQAYRPPWISNYPLADSALVMDPPRHTQLRALINRAFGTQVVTRIEPRVREFAQRIVQALPDGQEVNFVEHFSVLMPMYVIGELLGLSPEVQPRLLSWVEWLGQFTGVGPADTARQEAVRATVNEARGHFEQVLTERRRNPGDDLISDLLRARVEGESLSDTDLLGFMFLLLVGGMETTIHLLSHSALRLQLQPELMRQLREQPSLLPRFIDEVLRHETPAHGVMRLTSEETELGGVRLPKGTRLLMLMGSANRDEAQHPDPDRFDMNRTQSNLPFGHGIHFCIGSQLARLEARLSLEALLSRFTHLTAGTQSIQWNSSLVVRGPTRLSLIPHEN
>NZ_CP022098.1|WP_095985435.1|3034727_3040028_+|excinuclease-ABC-subunit-UvrA
MHKTHLVGARTHNLQSLSVDLAEGELVCLTGVSGSGKSSLALDTLYAEGQRRFVESFSPYARQFLERLERPPMDTLEPVAAGVAVDRRAPVKSSRSTVATLADVEAYLSALFTREAMPVCSECGVEAVRTDARVAAQAALAAEPDAPAVLTFPVRIADTADFIDARARLLKDGFHRLMVRGEVKELESLKPGEAADSAGVAYVIVDRVKLAAGQLGRVTAALESAWAQSNGEAVAFTPAGPRRIRRGLVCPKCAREFEPARPGLFSYQSPTGACPTCRGFGRTIGIDWDKVIPNPTLSLAKGAIRPWSGKTSEWERKMLGAYARQHRIPMDVPWGQLTAEQREQVLQGEGDYDGGRVYPGVRAWFRWMESRTYKMHVRVLLSRYRAYTLCESCKGARLNEAALAWRVGGLDLAAWHGLELADARTRLESLRTQTGQGELVRRELAGRLGYLARVGLGYLTLDRPARTLSGGEAQRVSLTAALGTSLTGALFVLDEPTVGLHPADVGPLTGAMAELATRGNIALVIEHDPLVIRSAHRVLELGPGAGKHGGRLCFDGSPQELARREDLPTGRLLSGTEDVKREPRTRTGELRVRNARAHNLQGVSVSVPLGVLCAITGPSGSGKSTLMDEVLYRHLARALGEKDAEVPGEADGVDGLEAIERITFVDQSPLGRTSRGNAATYTKAWDRLRDRFASEPEAEVRGLTPAHFSFNVDKGRCEACAGEGYETVEMQFLADVSLLCPVCRGRRFKEEVLAIRHQGWSVADVLEATVDEVLQRFEGDKVLARTLGPVSRLGLGYLKLGQPLSTLSGGEAQRLKLARALSSEAKGSLFLIDEPSAGLHDADVRQVLAALHELVDEGASVLVVDHDLVVMRGADWIIDLGPGGGRHGGLLVAEGTPEQVARGQGLTAAALRGELGAAATPVKRGREAAKAPAAIEVEHAREHNLQDVSCRIPLGKMTVVTGPSGSGKSSLVFDVVFAEGQRRFMETLTPYARQFLPSMPRPDVERIGGIPPSVALEQRTSRAGSTSTVATVTEVAHYLRLLFAKLGLPHCPNDGEPIAATTAEALYAQVLAMKGEGTVLAPAVRARKGTYLDVFTAAARAGIEKAFADGKEVSTDQPPQLVKSREHDIDLVMYQGRLAKLPREVFDKALTWGKGALKVRTAGARETLLSSERTCPVCGFSVPEMDPRWFSFNTKQGRCEACEGTGVQGGPEAQAEGKTEPCRTCEGSRLEPVPRAVRLEGSRYHEVVQQSVTAALGQVREWKFRGDQALLGEPSRQELLRRLDFLERVGLGYLSLDRNAATLSGGEMQRLRLSAQLGAGLTGAMYVLDEPTIGLHPRDTHRLLSNLRSLVHTGSTVLVVEHDTDTIRAADHLIELGPTGGRGGGRILAEGPPDQVLQNEEAPTARALREPAVLAAVPRGEPERWIELKGATAHNLKGVDLRIPVGRLTVVSGVSGSGKSTLVRQVLYPALREKLGLVTARPGAFKSLTGVEAIRRVMAVDQSPIGRTPRSVPATFLGLWDELRRAFAATPEAKVRGFGPTRFSFNSTSGGRCTACEGQGAISHEMSFLPDVVTPCEVCGGARFDAATLEVRYHGLTIGDALRLSADEAKDVFHALPKVAAPLTCLSDLGVGYLQLGQGSNTLSGGEAQRLKLAAELTASSRHEPTLYVLDEPTTGLHLGDVSKLIAFLHRLVDRGDTLVVIEHHPSVIASADYVVELGPEGGEAGGTRVAEGTPREVSRLKTATGRVLRSVFSADEPSRKAARGR
>NZ_CP022098.1|WP_095985436.1|3040055_3040871_-|hypothetical-protein
MSQGIHDMDERFELLGPLDESVGPARRISRQRSADLIQGALAAALPAAPEPTPAPPRKIPWKGVLVTSTCLGMMSAAAATGYGWWAHRSPKEEAPVVAPVRVVPPPAAPLAAEPVPEAAPSEEVAAEPPAPAVARTGPAPVAAEPEDLLRRANERRAAGQWREAETLYLRVIQSSPGTTSAYVAQVASGGLRLEHLGDAKGALRQYQQALRAKPRGMLSEEALQGVAESWRALGDTGREAQALEELLAAHPDSLLAGSARRRLDELRKVPQ
>NZ_CP022098.1|WP_157759138.1|3040867_3041389_-|sigma-70-family-RNA-polymerase-sigma-factor
MEGRRDAAESLLTELLPRVRNLVRYLVRGDHDVDDIAQEALIAILRGLPTWRREGSFKAWSDRVVARTTFAAMRKVRDSGTEPEAEPMELTVLSEEALPDDYVFRRDMVRLMDELSDEQRHALVLHYVLEMSVPEMTEELGIPFETVRSRLRLGRANLRALYARESGTNGGAE
>NZ_CP022098.1|WP_095985437.1|3041508_3042564_-|hypothetical-protein
MTRLLVVCVLVGWGTVSAAQEEPWAAVLRASSPEDTELAERLQGQLSDLPVVLRVNPGPTPSTEATEQWRTAVALAEQGPFRVVIWFHHEPAAIVVHVAEPATRRLLVRRVQVEPHQRKGRSAAAEAAALIVRSALKALVAGSPVGDVVEEVPEAPAPEPAPPPPAPAPASSPAPAREGWGVSVGWQGTLMGEGPLGQHGAQLGVGWEGARLRARVLLVASLPTPLSDEYTRVSLSRHALGAGVDAAVVSTEHFRLGAGLEVGLAGHLRGTEALAPDVQASPPRLTPSLYGAPTLAARWRGGPVALEASLALDVLTTVPTLGYLQQGTFIVRNSLWRAQPRFGLAILLGAH
>NZ_CP022098.1|WP_095985438.1|3042734_3043913_+|hypothetical-protein
MRWTHGLVLLAVTGACSVDDPVAILPGTDRAGYCASGEPIRLVEDGATGREICGGRLASRVFSRALCACGELVVSAPSALDAFQGSQGPGSPGGAGASVGANGGVQLTSELTVSGSLQAGDPGIVLGASLLSIQGELRDAGRLQGASSTVRVGGDAWVAGDVELQELTVGGVLSHPAERRLTVSQPPPRVRREPVGPFAPPCSCDAPEDVGAYVKNHVAAHHNADIGLAVDALEDFSGDAALELPCGRFYLTRIHGAGSLLLRVTGRAALLVDGDVDVGGLDVQLDEGAELDLLVAGGVSARGPVRMGSPGFPSRLRVYVAGAFDLDAGDPWNTLPESSELAGNFYLPRAPLDLSRRAEFSGSVFAQRVAASAGLFIHYDVDVLGLGERCSD
>NZ_CP022098.1|WP_095985439.1|3043922_3044561_-|SGNH/GDSL-hydrolase-family-protein
MSALSLRYVALGDSSGVGVGARQGGYVEHLFQRLRRTRTGVGLLNLSVSGATSATVLSGQLPRALRSSPHLVTLGVGINDLWRGVTPEQFESHFDSLAKGLASTGAAVLVSNLPDMSLAPVARLAANFLPLPLIAQRIGQFNAAVERVVARHGLIGVDLHGPSRVELPGSSDYFSADGFHPSDTGYLRMAEHFWPAVQRASERIGETTRATG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_12

3423311-3423417

Orphan

Consensus_repeat	Method
GAAGAAGGCCGAGGAGGAGGCGG	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP022098_12

>merge|NZ_CP022098|12|3423311-3423417|CRISPRCasFinder
GCGCAAGGAGAAGGAGGAGGCCGAGCGCCTGGCGCTCGAGGAGGAGGAGGCCCGGAAGAAGGCCGAGGAGGAGGCGGAAGCGGCGAAGAAGAAGGCCGAGGAGGAGG

>NZ_CP022098|12|12|3423311-3423417|CRISPRCasFinder
GCGCAAGGAGAAGGAGGAGGCCG	AGCGCCTGGCGCTCGAGGA
GGAGGAGGCCCGGAAGAAGGCCG	AGGAGGAGGCGGAAGCGGC
GAAGAAGAAGGCCGAGGAGGAGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_095985699.1\|3412233_3412725_-\|general-secretion-pathway-protein-GspG	unknown	unknown	gnl\|CDD\|377975
NZ_CP022098.1\|WP_095985705.1\|3421612_3422608_-\|ParB-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|366971
NZ_CP022098.1\|WP_095985712.1\|3429841_3432202_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274350
NZ_CP022098.1\|WP_095985707.1\|3424752_3426099_+\|cyclic-nucleotide-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|237999
NZ_CP022098.1\|WP_095985698.1\|3411514_3412237_-\|type-II-secretion-system-protein	unknown	unknown	gnl\|CDD\|225076
NZ_CP022098.1\|WP_095985701.1\|3414696_3416490_-\|type-II-secretion-system-ATPase-GspE	unknown	unknown	gnl\|CDD\|131585
NZ_CP022098.1\|WP_095985697.1\|3410660_3411518_-\|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl\|CDD\|377949
NZ_CP022098.1\|WP_095985700.1\|3413387_3414644_-\|type-II-secretion-system-inner-membrane-protein-GspF	unknown	unknown	gnl\|CDD\|273980
NZ_CP022098.1\|WP_095985710.1\|3428309_3429281_+\|homoserine-kinase	unknown	unknown	gnl\|CDD\|270702
NZ_CP022098.1\|WP_095985715.1\|3435374_3437138_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095985702.1\|3416493_3419040_-\|type-II-secretion-system-secretin-GspD	unknown	unknown	gnl\|CDD\|274175
NZ_CP022098.1\|WP_095985703.1\|3419067_3419985_-\|general-secretion-pathway-protein-GspC	unknown	unknown	gnl\|CDD\|273770
NZ_CP022098.1\|WP_095985714.1\|3433372_3435289_+\|DUF839-domain-containing-protein	unknown	unknown	gnl\|CDD\|225752
NZ_CP022098.1\|WP_095985704.1\|3420177_3421590_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NZ_CP022098.1\|WP_043432437.1\|3432227_3432623_+\|TIGR02266-family-protein	unknown	unknown	gnl\|CDD\|274060
NZ_CP022098.1\|WP_095985713.1\|3432630_3433203_+\|DUF192-domain-containing-protein	unknown	unknown	gnl\|CDD\|376876
NZ_CP022098.1\|WP_095985711.1\|3429300_3429768_-\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|379639
NZ_CP022098.1\|WP_095985708.1\|3426095_3426587_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095985709.1\|3426583_3428194_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|274350
NZ_CP022098.1\|WP_071899931.1\|3412741_3413161_-\|type-II-secretion-system-major-pseudopilin-GspG	unknown	unknown	gnl\|CDD\|377975

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095985699.1\|3412233_3412725_-\|general-secretion-pathway-protein-GspG	gnl\|CDD\|377975	pfam08334, T2SSG, Type II secretion system (T2SS), protein G. The Type II secretion system, also called Secretion-dependent pathway (SDP), is responsible for the transport of proteins across the outer membrane first exported to the periplasm by the Sec or Tat translocon in Gram-negative (diderm) bacteria. The T2SG family includes proteins such as EpsG (P45773) in Vibrio cholera, XcpT also called PddA (Q00514) in Pseudomonas aeruginosa or PulG (P15746)in Klebsiella pneumoniae. The PulG is thought to be anchored in the inner membrane with its C-terminus directed towards the periplasme. Together with other members of the Type II secretion machinery, it is thought to assemble into a pilus-like structure that may function as a dynamic mechanism to push secreted proteins out of the cell. The polypeptide is organized into a long N-terminal alpha-helix followed by a loop region that separates it from a C-terminal anti-parallel beta-sheet.	1.28063e-15
NZ_CP022098.1\|WP_095985705.1\|3421612_3422608_-\|ParB-N-terminal-domain-containing-protein	gnl\|CDD\|366971	pfam02195, ParBc, ParB-like nuclease domain.	2.52499e-07
NZ_CP022098.1\|WP_095985712.1\|3429841_3432202_-\|hypothetical-protein	gnl\|CDD\|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	7.53758e-06
NZ_CP022098.1\|WP_095985707.1\|3424752_3426099_+\|cyclic-nucleotide-binding-domain-containing-protein	gnl\|CDD\|237999	cd00038, CAP_ED, effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels.	2.4583e-21
NZ_CP022098.1\|WP_095985698.1\|3411514_3412237_-\|type-II-secretion-system-protein	gnl\|CDD\|225076	COG2165, PulG, Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion].	8.32556e-05
NZ_CP022098.1\|WP_095985701.1\|3414696_3416490_-\|type-II-secretion-system-ATPase-GspE	gnl\|CDD\|131585	TIGR02533, Type_II_secretion_system_protein_E, type II secretion system protein E. This family describes GspE, the E protein of the type II secretion system, also called the main terminal branch of the general secretion pathway. This model separates GspE from the PilB protein of type IV pilin biosynthesis. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	0
NZ_CP022098.1\|WP_095985697.1\|3410660_3411518_-\|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl\|CDD\|377949	pfam07963, N_methyl, Prokaryotic N-terminal methylation motif. This short motif directs methylation of the conserved phenylalanine residue. It is most often found at the N-terminus of pilins and other proteins involved in secretion, see pfam00114, pfam05946, pfam02501 and pfam07596.	9.96393e-06
NZ_CP022098.1\|WP_095985700.1\|3413387_3414644_-\|type-II-secretion-system-inner-membrane-protein-GspF	gnl\|CDD\|273980	TIGR02120, Putative_general_secretion_pathway_protein_F, type II secretion system protein F. This membrane protein is a component of the terminal branch complex of the general secretion pathway (GSP), also known as the"Type II" secretion pathway. The GSP transports proteins (generally virulence-associated cell wall hydrolases) across the outer membrase of the bacterial cell. Transport across the inner membrane is often, but not exclusively handled by the Sec system. This model was constructed from the broader subfamily model, pfam00482 which includes components of pilin complexes (PilC) as well as other related genes. GspF is nearly always gene clustered with other GSP subunits. Some genes from Xylella and Xanthomonas strains score below the trusted cutoff due to excessive divergence from the family such that a sequence from Deinococcus which does not appear to be GspF scores higher. [Protein fate, Protein and peptide secretion and trafficking].	2.59288e-166
NZ_CP022098.1\|WP_095985710.1\|3428309_3429281_+\|homoserine-kinase	gnl\|CDD\|270702	cd05153, HomoserineK_II, Type II Homoserine Kinase. This subfamily is composed of unusual homoserine kinases, from a subset of bacteria, which have a Protein Kinase fold. These proteins do not bear any similarity to the GHMP family homoserine kinases present in most bacteria and eukaryotes. Homoserine kinase catalyzes the transfer of the gamma-phosphoryl group from ATP to L-homoserine producing L-homoserine phosphate, an intermediate in the production of the amino acids threonine, methionine, and isoleucine. The Type II homoserine kinase subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	5.59077e-77
NZ_CP022098.1\|WP_095985702.1\|3416493_3419040_-\|type-II-secretion-system-secretin-GspD	gnl\|CDD\|274175	TIGR02517, Putative_type_II_secretion_system_protein_D, type II secretion system protein D. In Gram-negative bacteria, proteins that have first crossed the inner member by Sec-dependent protein transport can be exported across the outer membrane by type II secretion, also called the main terminal branch of the general secretion pathway. Members of this family are general secretion pathway protein D. In Yersinia enterocolitica, a second member of this family is part of a novel second type II secretion system specifically associated with virulence (See ). This family is closely homologous to the type IV pilus outer membrane secretin PilQ (TIGR02515) and to the type III secretion system pore YscC/HrcC (TIGR02516). [Protein fate, Protein and peptide secretion and trafficking].	0
NZ_CP022098.1\|WP_095985703.1\|3419067_3419985_-\|general-secretion-pathway-protein-GspC	gnl\|CDD\|273770	TIGR01713, Type_II_secretion_system_protein_C, type II secretion system protein C. This model represents GspC, protein C of the main terminal branch of the general secretion pathway, also called type II secretion. This system transports folded proteins across the bacterial outer membrane and is widely distributed in Gram-negative pathogens. [Protein fate, Protein and peptide secretion and trafficking].	3.79289e-17
NZ_CP022098.1\|WP_095985704.1\|3420177_3421590_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	0
NZ_CP022098.1\|WP_043432437.1\|3432227_3432623_+\|TIGR02266-family-protein	gnl\|CDD\|274060	TIGR02266, gmx_TIGR02266, Myxococcus xanthus paralogous domain TIGR02266. This domain is related to Type IV pilus assembly protein PilZ (pfam07238). It is found in at least 12 copies in Myxococcus xanthus DK 1622.	1.06693e-32
NZ_CP022098.1\|WP_095985713.1\|3432630_3433203_+\|DUF192-domain-containing-protein	gnl\|CDD\|376876	pfam02643, DUF192, Uncharacterized ACR, COG1430. Two structures have been solved for members of this large (>500 members) family of bacterial proteins present mostly in environmental bacteria and metagenomes (distant homologs are also present in several Plasmodium species). TOPSAN analysis for Structure 3pjy shows that there is much similarity with the other solved structure, Structure 3m7a, solved for UniProt:Q2GA55 (Saro_0823), a homolog of Thermotoga maritima TM1668, UniProt:Q9X1Z6., The homolog in Caulobacter crescentus (CC1388), UniProt:Q9A8G6, is associated with CspD, a cold shock protein (CC1387), UniProt:Q9A8G7. However, the genomic context of UniProt:Q2GA55 is most conserved with a putative xylose isomerase, suggesting a possible role in extracellular sugar processing. Saro_0821, UniProt:Q2GA57, is annotated as an AMP-dependent synthetase and ligase. Structure 3m7a structure corresponds to the C-terminal (27-165) fragment of the YP_496102 (Saro_0823) protein and it is structurally unique, as the best hits from Dali have a Z-score of 3.8 (1nt0, 2j1t, 3kq4) and it is thus a likely candidate for a new fold. Interestingly, many of the top Dali hits are involved in sugar metabolism. There are no obvious active site-like cavities on the protein surface of 3m7a (http://www.topsan.org/Proteins/JCSG/).	4.02969e-47
NZ_CP022098.1\|WP_095985714.1\|3433372_3435289_+\|DUF839-domain-containing-protein	gnl\|CDD\|225752	COG3211, PhoX, Predicted phosphatase [General function prediction only].	9.59288e-16
NZ_CP022098.1\|WP_095985711.1\|3429300_3429768_-\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|379639	pfam14534, DUF4440, Domain of unknown function (DUF4440).	1.65052e-05
NZ_CP022098.1\|WP_095985709.1\|3426583_3428194_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	6.6641e-08
NZ_CP022098.1\|WP_071899931.1\|3412741_3413161_-\|type-II-secretion-system-major-pseudopilin-GspG	gnl\|CDD\|377975	pfam08334, T2SSG, Type II secretion system (T2SS), protein G. The Type II secretion system, also called Secretion-dependent pathway (SDP), is responsible for the transport of proteins across the outer membrane first exported to the periplasm by the Sec or Tat translocon in Gram-negative (diderm) bacteria. The T2SG family includes proteins such as EpsG (P45773) in Vibrio cholera, XcpT also called PddA (Q00514) in Pseudomonas aeruginosa or PulG (P15746)in Klebsiella pneumoniae. The PulG is thought to be anchored in the inner membrane with its C-terminus directed towards the periplasme. Together with other members of the Type II secretion machinery, it is thought to assemble into a pilus-like structure that may function as a dynamic mechanism to push secreted proteins out of the cell. The polypeptide is organized into a long N-terminal alpha-helix followed by a loop region that separates it from a C-terminal anti-parallel beta-sheet.	2.8929e-32

>NZ_CP022098.1|WP_095985705.1|3421612_3422608_-|ParB-N-terminal-domain-containing-protein
MAAKSPRKKTASASTTTRRPRRKKAEPASKGLSPAEVVSEAHAPETELVQGILADGGQVVGLYRDPLGAHTVVFAALPIDKVEPTPYQRDVSEPHVKRLASAMERLDRFLDPIIAIRKEGRYWTPNGNHRLQASKLLGGKAIMALVLPEEDVAYQILALNTEKAHNLKERSLEVIRMHRGLTGARAGREADFAHLFEEPAFLTLGAAYEKRPRFSGGAYHPFIKRAEAFLPLPLAEALAVREARADRLLELDDTVAGVVDALKARGLQSPYLKNFVVARINFLRFKKDGPVEFEPTLTRMISSARKFNLDKVNREDLGRMSGPLLGSEEAE
>NZ_CP022098.1|WP_095985704.1|3420177_3421590_-|sigma-54-dependent-Fis-family-transcriptional-regulator
MTTPPAPTVLIVDDDRANLDSVARIFQREGLETLTASQGAEALERLRRPEVSVMVTDLMMPGMDGQELLKAARTIRPDVEVVLMTAYGTVETAVAAMKDGAYDFITKPLKRHALVKAVQKALEKHDLAAENRVLKAKLAEMSGPGGRAMVGQSPAFRAMMDTLRQAAPSTATVLLLGESGTGKELAARALHEQSQRAKGPFVAINCGALPESILEAELFGVERGAFTGAVSRREGRFERAHGGTLFLDEVGEMPLSAQVKLLRVLQEGELERLGGTQTVRVDVRIVAATNKDLVREVAEGRFREDLYYRLHVVEVRVPALASRREDIPLLADAFLRRFASKNGKVLRGFSPDALSALENYAWPGNVRELEHAVERAVVLARGDILEVGDLPETVRKGPVGSAGQLVIPIGTPMEEIERRVIHETLRHTKGDKTLAARLLGIAARTIYRKLEREASGSPSTGDGPGPLPDE
>NZ_CP022098.1|WP_095985703.1|3419067_3419985_-|general-secretion-pathway-protein-GspC
MELLFRKYFWTVNLVFILLVALLAAKTVNLFVESALTPLPSGEVAARQKARPTEMLASLDIRRMSELTGVKIPEPDPVVAEPTQPVADPNAAPVKSNLRVKLLGTLVASDKLWSVASIQDMNNQRSYTYMVGDTIESSSAQVIDIERLRVIVLNNGRKEYIDGQPGDGAVATYTPPPLPTNTPVQTPNAGLGNGIRATGENDYEIPRTEIDRTLANLNDVAMQARIVPAFKDGQAQGFKLFSIRPDSIYSKIGVQNGDVIKRINGFELNSPEKALEVYTKLKEASRIEIELERNGSSIRKNYTIR
>NZ_CP022098.1|WP_095985702.1|3416493_3419040_-|type-II-secretion-system-secretin-GspD
MKTLPSWLLLLSLAMASPALAQRPTTPGSADRQITPQGTNPEGNGTTVRPTPTCEEVRRRARYNIYFDKVDIEKLVQTVSDATCRTFILPENVRGKISILGPENGRVEVDADQFYAAFLAALDANGLAVYQHGRFLKIVDKRAAKQNPIPTLMDDEGAYTTNEQMITKLFRIKNVEVEPLRGVLQQLVSKDGDTIPYPPDIVIINDVGSNVRRLERIIEQLDTRSASDEVRIIQVQYATAQDVAATVQKLFEQKGGNPNPGMPQGRTPRGAPAVMTPPGGSMGETMPASGPGGDSTSGPVTFSQMIPDERTNKLIVVASPAAFERIQSLVRELDIPTAGTERINVYPLENANSEEIASTLQTLSQGTGNRPRSPVPVPGVPGAPRQPGSGGAAELFSGEVKISADKGTNSLVIIASQSDYRSLVRVIRELDKPRRQVFVEAVIMEVNLDRKQDFGLNVHSGYQVGTPLGTGSGLVGTKYSTSGLPPSFSLANLASFGGFLAGLQGPVIPELKALGIDIPAFGIVLHAFQQSSDVNVLSTPHLLTSDNEEAEITVGQNVPFQSGFSPSSLGTTGTTTGTGNPVNSLLGSLGGLSSLYAPITRQNVELKLTIKPQINESDFIRMAITEQTEEIASTDAVLGPTTSKRSAKTTVVAKDQETVVIGGIMQERTIETVAKVPILGDVPLLGHLFRSTNKSKTKTNLLLFLTPYIIREQSDFRRIFERKMQERQQFVEQFYGQVAGYDVPVDFERKSGPLGRMRRTVLTEEQKAENGGPGMPGERVLRPANSTPAPSSTPAPAGSAVAPGEVSPGARGLQTPATTETPEVRPPSAPPPEDPERLRIQPDTGNQE
>NZ_CP022098.1|WP_095985701.1|3414696_3416490_-|type-II-secretion-system-ATPase-GspE
MSLLADAPPAVPPDAATQVIAQGPTTLCGRPLGEILRRTSGLTEDKLQEALQLQADKGGRLGEVLVGLKALSEEEVAKALGLQLDLPYLARIFIEEIDPELIKRVPINFAKQARILPLSVEEGAVALAVADPLDTTVLDHARMLLGQDVLPRIALASTIVDAINSVYDRATNEAEQLVGELEAQDLDSIAQEIDEVKDLIDVEGDEAPVIRLVNSVLFRAAKERASDIHIEPMERELMVRFRVDGVLQEIIKPPKRYQSAIVSRVKVMGQLNIAEKRLPQDGRIRIKMAGRDIDIRLSTIPTTYGERIVMRLLDKNTTLLDLTELGMAKSMLDQMEHLIRRPHGIVLVTGPTGSGKTTTLYGALSRINTPDLNILTVEDPVEYQLKGIGQMAISPKIGLTFAQGLRSFLRQDPDVIMVGEIRDKETAEIAIQASLTGHLVFSTVHTNDAASAITRLVDMGVEPFLVASSLTGVLAQRLVRRVCPDCRVQYTPTDEELREISLNRATLKERHGVEKIYKAAGCTSCSQNGYRGRTGIYELLFVDDTVRQLALKNVDSSTIKKAAMSNGMHTLLDDGARKIALGETTIAEVLSITQEDL
>NZ_CP022098.1|WP_095985700.1|3413387_3414644_-|type-II-secretion-system-inner-membrane-protein-GspF
MPVFEYKALDSAGKSIRGMLEADSAKTLRSQLRKDNKFLTEVIGQADGNRAAVRKGANAAQADREVNFGKLARGRISTDDIAITTRQLATLLGAGVTLVEALTALVDQVEKERLKLILSEVKSRVNEGSSLADALATHQKVFGSLYVNMIRAGEHSGALDKVLMRLADFTESQSKLQQKIVGTMTYPAIMVLVGVGILTLLMVVVIPKVTKIFTTMKATLPWTTRLLIWTSTMLQDWWFIIFPTLFAIIFGLTSYFRSPKGKPVWDRYALKAPIFGGLLRLLAISRFARTLATLLKSGVPLLTAMDITKAVITNSVLADVVEKARDAIREGESIATPLKRSGEFPPLVYHMVSIGEKSGQLEDMLLSVADNYENQVNVRIGALTSMLEPLLTVFMGVMIAFVAFSVLMPILQVNSAIR
>NZ_CP022098.1|WP_071899931.1|3412741_3413161_-|type-II-secretion-system-major-pseudopilin-GspG
MSDTKTKRQQQRRRRGMTLIEIMVVITILGLIMAAVGVSVIPKLEEAKQDTARLDIKNIQSALKLYYTKKGKYPDTGTGLRALVETQNLDKIPLDPWGHEYVYMNEGGKPVLISYGADGTQGGEGPDADISSRDATAQK
>NZ_CP022098.1|WP_095985699.1|3412233_3412725_-|general-secretion-pathway-protein-GspG
MTTEHATTTPRLAEPTAARPTRTGRLIVAGVIVAGSAGAFAIASLTFDKTLTPLQRQARAEIRGLEGYFKSFHRITGRFPSQAENFYPLLQVGLIKEIPQDPWGNAYQYRMSEKGNGYIMSYGSDGVAGGSGDAADLISGGVLDNAMVGTEEQQRQAAQEEAR
>NZ_CP022098.1|WP_095985698.1|3411514_3412237_-|type-II-secretion-system-protein
MNSARAVRRTRERGLTLIEMSIALGIAAVLFAAVTVSVGAITGAKAKASASELAGVIRSLYDTAALTGKTCRLVFELADPKTEEGVSRYRAECAAGNVTTARDRDTQLREDDTAREDAKKGRPRNDPRRNFTRGDDDEPGLDELMAQEQDRVENAARFSEFTGEEISPRQLPAGVNVSVWTRHQREPADKGLAYLYFFPQGFTEKAQVYVRQGENVWTLAISPLTGKVNIVGEALEVPRS
>NZ_CP022098.1|WP_095985697.1|3410660_3411518_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MRRTRGFTLLETVVALAILALALMAIFDINSGAVANHAYAKKLTVATLLARSKMTDLEQKLYDEGFSNDDQEESGDFSAEGWEGFKWRAKIIAPQTEGVSPEQLIGAIFNLPIGEGGDLSGLASMFGGGGTGKDGSSSSQTTANPMAGAAMGMAQPMFTQMVQQITQTVRELHLTVYWREGTQVESLDLVTHMVSLGPGSDRNGGFQPNNGTQPPGMSEQWVDPATGFIVQNAAPGPNGQMINPANGQPLMRRTDFLSRSGGRGGGQPGAGGIVPGGGQLQGRTR
>NZ_CP022098.1|WP_095985707.1|3424752_3426099_+|cyclic-nucleotide-binding-domain-containing-protein
MNESSLRELGWDLLEDRQFERALAVFAESVRRVPADHRSRMMAARCLAELGERERAVTVYHACAEGLLRRDYLLSAMAACKLGLELAPQERRLRDTLVRLHARASRSAAGRASVPPPLPPETLYDGKVETDLMGMVGEELSDRAIEVLAAPDPGGSANPADRPPLPLFAELDLEAFIDLVTRMSYRSIKADEVVSAENDSPDRLYVIVAGKAEVTRQVGEEARTLGFLGGGSIFGELSLLTGAPSTATVTAVVDMEVFEVRREHLNAVAKSHPSVPQVLAQFAHKRMERNLIATSPLFQPMPESERAALLQRFDFRALPPGEKVLVEGEHSPGLFLVLAGELVVQKEDPAGGIVRLGVLREGEVAGEISLLTGLRATATVVSARKTAAAFLARAAFHDLVKQYPHIQKYLEQLSDRRLKQIGEALRPAEILDADELLEVDAPGTGSVG
>NZ_CP022098.1|WP_095985708.1|3426095_3426587_+|hypothetical-protein
MTLSRGQVLGVVLALLAAGVVLALWPQQEPGVKDAITRRVLQMSDAAERKDMADLMDGVAESFRSEQGWDKQQLKGVLLGQVLRGQWVRVFVKDLHVTEVSPSQGDVQVKLIFGRSEADTLESLARDSVLSAYLIEARFDKQADGEWRVVGAKHRSLSPGELF
>NZ_CP022098.1|WP_095985709.1|3426583_3428194_-|tetratricopeptide-repeat-protein
MATSNATPGGPRGGHGRQSFRGALVQVGLVALLFAGAVAYLVHQGSVRREVNTRLKAARALSVRDNPVDLRQSLVELDALFLLDDQVKDAQALAADVNTRLWLEHQQPEAQARAREHQARAEALDSRSGERYGTHARLLLAEGKTEQAGKYLEELRAQGAKNPKLALAEAQVLIARGRLAEARQAFARASEAAWREPRYAQAHGEALLDEGLAAQAAEAFKKATVSSPGHLRARLSLALARLYQGTGQEEARKTVADVLSREAELSPPLKARALSVRAALALVEDRPGEALKAAGEALAASPDEYQALFLRARALARRGDAGAREAFLAAVERRRTAPLLYLEGARVLREASDGEGALMLLDAYETVFRDVRVPAGEGQEVGALERDERYWLARGGVMETLAREDAALEAYDRALAVKGVGRARAQYAKAALLLSRGDTASAQPLLAELTPENGMGALPEAYEAMGRLLFSQGEFAQGCQNYYVGLSRAHQQGESPEELQHKAAAVERRLTDSGQATMARTWKTETDALLRQVGGL
>NZ_CP022098.1|WP_095985710.1|3428309_3429281_+|homoserine-kinase
MALYTQLDAAALHRLVDAYALGTVQELTGIPQGSINSNFRLVTSAGRYFVRHTTVRSADDLNFEAGLLALLNASHFPSPRLVSTRDGAPFLELQGGRVVVFAWLEGEELTRERLTPEHLEALGVELGKLHRVGASYLGVRANPYGPEVVRGWLKGLEQHPDAELSAIARELHGHLARAESLRGGQEPRGVIHADIFLDNVKWLGDRVSALFDFEMACQDALTLDVAITLNAWCFDSGRYRPELCQGLLRGYQVQRTLLPAERESLFGHALFGAVRYTASRIRDFHLSGLPPDKLAPKDFRTYLARARALHQMGPEGLRALVGV
>NZ_CP022098.1|WP_095985711.1|3429300_3429768_-|nuclear-transport-factor-2-family-protein
MNVRPLFVTVLLVLSACGPRYIPGTQINDTQDTRAILKVLERYRVAVEARDAKAIQALVSPSFRDNAGTEDPLDDLTAENLAQTLPALLARVDAPRLEMDVRRVDVKRDGWATVIYYWNASWRAPGLMERPQRDSELEQMVLQREDGEWRIVSGI
>NZ_CP022098.1|WP_095985712.1|3429841_3432202_-|hypothetical-protein
MRQVLIRATNLLRRPSGLVPAGILALGGSALVLLPLFGVPGLELGLALSIGVGLLGGGLGIASVHQERRLLATRAASPDAAEPPRPGASMRLAWRALAPALLVNLAVLVPPFLTATLYAWLGTRCDPFALAGFYPLLTLPSAGLASVVGVFCGFATRRAGRAGLLYAGILLVSLCVTAWPIVLGPQVYAFNAFLGHLPGPLYDETLSLSSALLWFRAETLLLIFAVHALTELLLDPVQARLGRPRPRVGPLLLLGLTLGPVVLIEAHATDLGLRMSDATLRERLGAVRETEHFEFIYPRALRSEDVDRRARDLEFRYAQLARFLGRVPEGRIRVWLYSTDDEKQRLVGAGRTQFAKPWRQELHINGRDYPHPTLKHELAHVMAAPSGSGPFRVTTRLGVWPLMGVIEGMAVAADNPVQGDLTLDEWAAGMRRQKLAPDIRKLVGPEGFYQSAPARAYTLVGSFLRYLADTHGPDKLRQLYAHADFEATYGRPLDALATEWERHLDALPLDEATVNRAFQRFRTGSLFTRSCAREVARLQDEARELLAADPPRALAAYERAALLQPQEPSFRMGQALALDRLERPDEAAQVLAQVAEQVKDQPALKAEVALAQADVESRRGQFAPARAFLEHVLTLAPSPEVTRTAQVKLAALDSPVRATLQAYFQNEAEELRLLRLSTALQTAPQDIYVHYLLGRRLLQVGAPVAALPHLSRTIEGEAPAAIRREARRLQVQAAYLAGDCGAVRHAVGTLPDEGPALRALVTEWAERCDFEERLYGGPLVPRDAFR
>NZ_CP022098.1|WP_043432437.1|3432227_3432623_+|TIGR02266-family-protein
MAEQKTGAESRQFARAPIELKVDYKKLNSFFADYTKNISKGGTFIKTKKPLPIGTRFLFKLTVPQRDGPFELLGEVVWSQGEAEEPGMGIRFIYNDERQRSEFEGVVERLMADSLGTQLTEKLLNKQLHME
>NZ_CP022098.1|WP_095985713.1|3432630_3433203_+|DUF192-domain-containing-protein
MNRRHGAWGLGVVVGLTCCRPAEARDKVEHQKVEHPTARKVKHQQVKHQDGEDDVGPTLPRARVLLEDVSGGVQVVDVEVAATPDTRSRGLMWRKELPEGQGMLFIFPDEEVQRFWMRNTLIPLDMIFINSAGRVVGIIENAAPRSLVQRFVSEPGRYVLEVPGGWSRKVGLARGGHVRFEGVERIPVIP
>NZ_CP022098.1|WP_095985714.1|3433372_3435289_+|DUF839-domain-containing-protein
MTVLALSACSGGTGPQGPQGPQGEPGAPGAPGTPGDNGAPGSGRSLTFAPINAASTQAEKRVVTASSKASVNGREIPIGYETVLRSGQDLGGQRFGRMIQKDGKPVKNTDGSDFISPSNDFSSLLQAGNRLFEVTHFETTPAAMYLSELRQSPDGKLSALSTRPIDFSGVDGLWTPCAGSVSPWGTHLGSEEYPPDARATEKAATVSGLSSSERSMLRYWGLDATTATLEQARAVYSPYRYGYVVEVAVDGSGTTKVTKHYAAGRRALELAYVMPDRKTVYLTDDGTNDAFYMFVATRAGDLSEGKLYAARWFQTSAAGQGAGRADLYWLPLGPSATDAQVKALIDGGIRFSDIFETETQASDGTCPSASQGFRAVNTETGRECLRLKPDQEVAASRLESRRYAAYVGGTTEFRKTEGLAYNPATHRLYVAFSEVNNGMTHSHASRDLGGPNHVQLAQNDCGAVYELVVSPNAEVGSDYVAESASALVEGAWLKAPGASLYPSNSPYYDPTFTLPDSNGVAQPATGNVCGINGIANPDNLSFIDGYDTLLIGEDSTDGHQNDMVWAYNVVTRQLTRIFSTPYGSETTGVYFYPDINGHAYIKTQIQHPYGESDTDKLGADASAAQSYTGYIGPFPAMK
>NZ_CP022098.1|WP_095985715.1|3435374_3437138_+|hypothetical-protein
MDRRRVTSVVWVLGLFAAGSVAAWRSTRLPPPAPDPLSQVRESLAAAQPATLEEAAPRLSNPSAYLPAQCYADTRSTEGGRTRNGCFACHQTPRAPNYVEDAELQTVLTVSRYAEDNRWTNVLQPPPPVEWSETEVLAWVRTSNYVDARGGLRLASALAKPPAAWDANGDGRWEGYTPDCWFQPDGEGFDHSPDGAMTGWRAFAYAPFPGMFWPTNGSAGDVFIRLPEAFRRDAAGRESKAIYRLNLAILEAFIRREDVPVPATDERELGSDLDGDGVLGTARRVAFVWPPRPGRAFGYVGQAAGLDAAREGWPAAGLYPRGTEFLHSLRYLDVEGGQVRMAARMKELRYMRKTRWRTYSELQLAAEAEAREKMKHPDVLKKVHADVERGVGTGTGWVMQGFIEAADGELRPQNVEETTACIGCHGGVGATTDSTFSFARKYAPGMAVQEGWYHWGTRGLKGLPEPRRADGRGEYAHWLEQVGGGDDYGSNDEVQARFFRGDGTLRPDAVKALTRDISTLLVPSPARALRLDRAYLGLAKAQRFERGRDVVVGTTPHVRQRLEQDGETGLEEAVLPAWVPPERTASR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_13

4717797-4717882

Orphan

Consensus_repeat	Method
GGCTTCCAGCTCGGCCACGCGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022098_13

>merge|NZ_CP022098|13|4717797-4717882|CRISPRCasFinder
GGCTTCCAGCTCGGCCACGCGGGACTCGGCGGAACTCGCCTGGCTCTGGGCATCCTCCAGGGTGCCTTCCAGCTCGGCCACGCGGG

>NZ_CP022098|13|13|4717797-4717882|CRISPRCasFinder
GGCTTCCAGCTCGGCCACGCGGG	ACTCGGCGGAACTCGCCTGGCTCTGGGCATCCTCCAGGGT
GCCTTCCAGCTCGGCCACGCGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_095986577.1\|4704598_4705615_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|273596
NZ_CP022098.1\|WP_095986582.1\|4712636_4713962_+\|homoserine-dehydrogenase	unknown	unknown	gnl\|CDD\|235783
NZ_CP022098.1\|WP_095986594.1\|4730916_4731897_+\|chemotaxis-response-regulator-protein-glutamate-methylesterase	unknown	unknown	gnl\|CDD\|319751
NZ_CP022098.1\|WP_095986589.1\|4721996_4723301_+\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|100105
NZ_CP022098.1\|WP_095986578.1\|4705671_4706577_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095986581.1\|4712025_4712640_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_002632097.1\|4726434_4726917_+\|Positive-regulator-of-CheA-protein-activity-(CheW)	unknown	unknown	gnl\|CDD\|238374
NZ_CP022098.1\|WP_095986585.1\|4715859_4717014_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095986593.1\|4728575_4730870_+\|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl\|CDD\|223716
NZ_CP022098.1\|WP_095992111.1\|4711083_4711995_+\|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|379311
NZ_CP022098.1\|WP_095986590.1\|4723310_4724759_+\|amidase	unknown	unknown	gnl\|CDD\|223232
NZ_CP022098.1\|WP_095986584.1\|4715092_4715863_+\|type-III-pantothenate-kinase	unknown	unknown	gnl\|CDD\|237349
NZ_CP022098.1\|WP_095986580.1\|4708868_4711016_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368272
NZ_CP022098.1\|WP_095986588.1\|4720724_4721861_-\|alanine-dehydrogenase	unknown	unknown	gnl\|CDD\|240630
NZ_CP022098.1\|WP_002626150.1\|4719859_4720516_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|236608
NZ_CP022098.1\|WP_095986583.1\|4714075_4715077_+\|biotin--[acetyl-CoA-carboxylase]-ligase	unknown	unknown	gnl\|CDD\|237010
NZ_CP022098.1\|WP_095986591.1\|4726913_4727306_+\|Frizzy-aggregation-protein-FrzB	unknown	unknown	gnl\|CDD\|214588
NZ_CP022098.1\|WP_095986592.1\|4727292_4728513_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|214599
NZ_CP022098.1\|WP_095986579.1\|4706580_4708767_-\|PQQ-binding-like-beta-propeller-repeat-protein	unknown	unknown	gnl\|CDD\|379140
NZ_CP022098.1\|WP_095986587.1\|4718959_4719790_-\|transmembrane-regulator-PrtR	unknown	unknown	gnl\|CDD\|227949

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095986577.1\|4704598_4705615_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|273596	TIGR01392, Homoserine_O-acetyltransferase, homoserine O-acetyltransferase. This family describes homoserine-O-acetyltransferase, an enzyme of methionine biosynthesis. This model has been rebuilt to identify sequences more broadly, including a number of sequences suggested to be homoserine O-acetyltransferase based on proximity to other Met biosynthesis genes. [Amino acid biosynthesis, Aspartate family].	1.12613e-57
NZ_CP022098.1\|WP_095986582.1\|4712636_4713962_+\|homoserine-dehydrogenase	gnl\|CDD\|235783	PRK06349, PRK06349, homoserine dehydrogenase; Provisional.	0
NZ_CP022098.1\|WP_095986594.1\|4730916_4731897_+\|chemotaxis-response-regulator-protein-glutamate-methylesterase	gnl\|CDD\|319751	cd16432, CheB_Rec, Chemotaxis response regulator protein-glutamate methylesterase, CheB, with N-terminal REC domain. This family contains the methylesterase CheB (EC 3.1.1.61; also known as CheB methylesterase, chemotaxis-specific methylesterase, methyl-accepting chemotaxis protein methyl-esterase, or protein methyl-esterase) domain with a REC domain at the N-terminus. CheB is a phosphorylation-activated response regulator involved in reversible modification of bacterial chemotaxis receptors. Signaling output of the chemotaxis receptors is modulated by CheB and methyltransferase CheR by controlling the level of receptor methylation. The N-terminal regulatory (REC) domain blocks the active site of the C-terminal domain until it is phosphorylated. Reversible methylation of transmembrane chemoreceptors plays an important role in ligand-dependent signaling and cellular adaptation in bacterial chemotaxis. Phosphorylated CheB catalyzes deamidation of specific glutamine residues in the cytoplasmic region of the chemoreceptors and demethylation of specific methyl glutamate residues introduced into the chemoreceptors by CheR.	1.22679e-94
NZ_CP022098.1\|WP_095986589.1\|4721996_4723301_+\|radical-SAM-protein	gnl\|CDD\|100105	cd01335, Radical_SAM, Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster. Mechanistically, they share the transfer of a single electron from the iron-sulfur cluster to SAM, which leads to its reductive cleavage to methionine and a 5'-deoxyadenosyl radical, which, in turn, abstracts a hydrogen from the appropriately positioned carbon atom. Depending on the enzyme, SAM is consumed during this process or it is restored and reused. Radical SAM enzymes catalyze steps in metabolism, DNA repair, the biosynthesis of vitamins and coenzymes, and the biosynthesis of many antibiotics. Examples are biotin synthase (BioB), lipoyl synthase (LipA), pyruvate formate-lyase (PFL), coproporphyrinogen oxidase (HemN), lysine 2,3-aminomutase (LAM), anaerobic ribonucleotide reductase (ARR), and MoaA, an enzyme of the biosynthesis of molybdopterin.	1.36205e-12
NZ_CP022098.1\|WP_002632097.1\|4726434_4726917_+\|Positive-regulator-of-CheA-protein-activity-(CheW)	gnl\|CDD\|238374	cd00732, CheW, CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together with CheA and the methyl-accepting chemotaxis proteins (MCPs), which are involved in response modulation.	2.63721e-35
NZ_CP022098.1\|WP_095986593.1\|4728575_4730870_+\|hybrid-sensor-histidine-kinase/response-regulator	gnl\|CDD\|223716	COG0643, CheA, Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms].	2.54864e-118
NZ_CP022098.1\|WP_095992111.1\|4711083_4711995_+\|HEAT-repeat-domain-containing-protein	gnl\|CDD\|379311	pfam13646, HEAT_2, HEAT repeats. This family includes multiple HEAT repeats.	2.06876e-08
NZ_CP022098.1\|WP_095986590.1\|4723310_4724759_+\|amidase	gnl\|CDD\|223232	COG0154, GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis].	5.56804e-134
NZ_CP022098.1\|WP_095986584.1\|4715092_4715863_+\|type-III-pantothenate-kinase	gnl\|CDD\|237349	PRK13321, PRK13321, type III pantothenate kinase.	7.41219e-153
NZ_CP022098.1\|WP_095986580.1\|4708868_4711016_+\|hypothetical-protein	gnl\|CDD\|368272	pfam05066, HARE-HTH, HB1, ASXL, restriction endonuclease HTH domain. A winged helix-turn-helix domain present in the plant HB1, vertebrate ASXL, the H. pylori restriction endonuclease HpyAIII(HgrA), the RNA polymerase delta subunit(RpoE) of Gram positive bacteria and several restriction endonucleases. The domain is distinguished by the presence of a conserved one-turn helix between helix-3 and the preceding conserved turn. Its diverse architectures in eukaryotic species with extensive gene body methylation is suggestive of a chromatin function. The genetic interaction of the HARE-HTH containing ASXL with the methyl cytosine hydroxylating Tet2 protein is suggestive of a role for the domain in discriminating sequences with DNA modifications such as hmC. Bacterial versions include fusions to diverse restriction endonucleases, and a DNA glycosylase where it may play a similar role in detecting modified DNA. Certain bacterial version of the HARE-HTH domain show fusions to the helix-hairpin-helix domain of the RNA polymerase alpha subunit and the HTH domains found in regions 3 and 4 of the sigma factors. These versions are predicted to function as a novel inhibitor of the binding of RNA polymerase to transcription start sites, similar to the Bacillus delta protein.	9.30964e-16
NZ_CP022098.1\|WP_095986588.1\|4720724_4721861_-\|alanine-dehydrogenase	gnl\|CDD\|240630	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains. Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.	0
NZ_CP022098.1\|WP_002626150.1\|4719859_4720516_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|236608	PRK09652, PRK09652, RNA polymerase sigma factor RpoE; Provisional.	2.08096e-58
NZ_CP022098.1\|WP_095986583.1\|4714075_4715077_+\|biotin--[acetyl-CoA-carboxylase]-ligase	gnl\|CDD\|237010	PRK11886, PRK11886, bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA.	4.54674e-86
NZ_CP022098.1\|WP_095986591.1\|4726913_4727306_+\|Frizzy-aggregation-protein-FrzB	gnl\|CDD\|214588	smart00260, CheW, Two component signalling adaptor domain.	0.00314857
NZ_CP022098.1\|WP_095986592.1\|4727292_4728513_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	3.55051e-57
NZ_CP022098.1\|WP_095986579.1\|4706580_4708767_-\|PQQ-binding-like-beta-propeller-repeat-protein	gnl\|CDD\|379140	pfam13360, PQQ_2, PQQ-like domain. This domain contains several repeats of the PQQ repeat.	6.18718e-11
NZ_CP022098.1\|WP_095986587.1\|4718959_4719790_-\|transmembrane-regulator-PrtR	gnl\|CDD\|227949	COG5662, COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription].	3.60549e-09

>NZ_CP022098.1|WP_095986585.1|4715859_4717014_+|hypothetical-protein
MSTAPQQSPAATPAGCPISAEVLPPNMRKHVDPAAPVPLRMMAAKAMVPLAPVDMLGALFMLTFDADASVRETATKTAAALPDRFSAGLRDENVAPQVLGWLLPLLRSKDALAEMLVLNTTTPDEAVAQVARDCGAKVAEIIGQNQLRVLRHEDILRQLCANPNASPALIDNVCDFAVRSGLTLTDVPQVQAARVRLFGPQAAAAPPEPGPTAEEVIAEFQADGAQEKADDEDPNPPPMEETKRQSLTQRIMKMSIAQKIKLATLGNKEARSHLIRDTNKLVCTAVIRSPRITPGEVLNCAGNKAVNEEILRYIYSSREWTKNYKIKMALLKNPKLPLAVGMKFLNTLRENDVKDLSRDKNVPSGLQGVAKKMLEKKNEKKEEK
>NZ_CP022098.1|WP_095986584.1|4715092_4715863_+|type-III-pantothenate-kinase
MLLAIDVGNTNTVLGVYDGQRLLSHWRVETSARRTSDELGILLRQLFLASGIEPGAVNAVAVSSVVPPLQSHLGRMSERYFKTRPLFVGPGVKTGMPILYDNPREVGADRIVNAVAAYDKHHRGLIVVDFGTATTFDAVTPRGEYLGGSICPGIHIGMEALFQNASKLPRVEFARPPHVVGRNTVHSIQSGLFFGYVAMVDGLCARMKAELGFETHVVATGGLAPLVAGASTHIQEVDEFLTLEGLRIIYGRNHAP
>NZ_CP022098.1|WP_095986583.1|4714075_4715077_+|biotin--[acetyl-CoA-carboxylase]-ligase
MGVESAEQTYEEIILGFLVEGRDGFCSGEALSDKLGLSRTAVWKHVESLRGKGYRIDAVPARGYRLVDVPDKLTPLELAPLLSTHHLGQQIHFHESLPSTNVTAFQLAADGAEHGEVVITEQQTAGKGRRGRVWTSPPGVNLYFSAILRPELPPQRASELTLVAAVALAETLREQDADARIKWPNDVQLDGRKVAGILTELSADPDQVHFVVLGVGVNLNSGPEDFPPELAETATSLSRVLGRRVNRALFTSSLWGRLEEWLDLHHEVGFEPVRQRWVELSSTLHQEVRVRTDRAELRGVAEDIDAAGALLVRTPEGRLERVLAGDVEQVRPR
>NZ_CP022098.1|WP_095986582.1|4712636_4713962_+|homoserine-dehydrogenase
MKEIGIALLGLGNVGLGTYRILTQHAKDIERRLGARVRVHHVLVREPGRSRPEDVPSALLTHDMKTILANPEVSVVVELMGGLSPAREYVEQAIASGRHVVTANKALLSAHGEAIFSSAIARGVDVHFEAAVCGGIPIIRTLREALASDRVESLTGIVNGTTNFILSAMADEGATYADALRRAQELGYAEADPTLDVSGMDAAQKLCLLASLAFSARVSPESVLVEGISTLTPADIAHGREAGFVLKLLARASRAPDGLDVRVHPAFIPAASPLADVKGGFNAVLLQSAALGASLFSGLGAGALPTGSAVVSDIIDTCRGLLAGVSGRLPLPCAPNVQDVPLLPPGERRGPTYLRFSVSDEPGVLGRIASVLGEKGVSINSVLQRPPRPEDTHATIVVFTHDTREADVIAAVQWIDSLRSTRAPTQVIRIEEGPGLLLSGR
>NZ_CP022098.1|WP_095986581.1|4712025_4712640_+|hypothetical-protein
MALGAAWVLGAGACAGRQPVADSASGSSSRATESLSAYYPLAVGNRWTYRVNGREDKPVTVEVLKEEDGYFHDSQGGQLTVDAFGVRDRKRYLLRGPLTEGSQWTNVVSVASTERYRILQADVPCETRAGAFPACVRVEASNRVDANTTLINALTFARGVGLVRMELFVQKSNGERMPQTSLELESYQLNPGAPTARGQAEEAP
>NZ_CP022098.1|WP_095992111.1|4711083_4711995_+|HEAT-repeat-domain-containing-protein
MLPFLVALLLLGACRSREPRFPVEHVSLKGATVIDNGLLGWSASDIQALFTDVLRDSRRFELLSEEAPERSEPGPWSFTLELPFTREALKDGGTYSFAEVGVTLVMERRSGEGTQRYQVVGLGEVRVESKGAEARRKALREALRRGLVQVVDAARLQLAAVGRPDGALVMDLQSPDERVRDFALRVLAERRNPAAAPMLLRQLQDEDLQVARQAMGALVEMKESSAVPALIELVKERDVGFMQEVVFAIGEIGGAEAEAYLFTVAQGHDQPDVQAAAQQALDTLYAAHKLATPEARGTDRAEH
>NZ_CP022098.1|WP_095986580.1|4708868_4711016_+|hypothetical-protein
MTFYEAALRVLESEGRPLHFLEITERSIAQNLLSHVGKTPELTMLSRLAAMARRTRDRKVIVTAKDTFALTDWSLPEDLEALAHTGVLEAHPEEGLPPLRPTERHPDPRVDNVRVAGRGSERKQRRQDEEEGRGGRRRRFPPMPEVVFEILSEADQSLRPEQLLEQARAKELAAEDATVEALLTALLEDNQRRIDAGRRPQFSFSTETGAVTLERAGSPSEAPPLELQAAFAAALGIPLEDGRPVLNRPSATAAAPEALADAALLTAARSAVKDARKAVARSLRKRLGELDVGTFEKSVVKMMHALGFRELKVAKRSKEGPLLTARKREGSVDLRFAIRMLKGAPALDRKAVQELRKDLGHYSAQVGLLACAGEARGDARTEAQASGSLVMLWCGDALGEKFLEAKAAVSVTTVELYDVDERFFEVAKLEAEEAQKRREERQREKLARADEGEEAGGEGESRGAVSVEATDDSQKRREERREERQRERDARREERRQARKAAQEEPGTESAPAAAAPEAAPTAPAGLSEEEEGDEEGEDEDLEAASAFVAGGAGEAGSPEEAAASGERKRRRRRRRGRRGRGGRGPEGAPGEPGAAAAVEGAAAVAVTTEAPVSTTTVETTTGQLTTQQESALVVVTAVEAGPVEGVSAPPVEAQGSLPLDVPPAAPAVAVEVSPAPEAAPAAPEAAPATPEEPKPQGEPGPSSSNGGSPEGGTA
>NZ_CP022098.1|WP_095986579.1|4706580_4708767_-|PQQ-binding-like-beta-propeller-repeat-protein
MIRFRIGHRWKREPAEAPHDSVSLELDGVNLLPGAVEEPLVDVVPALLAALAALHAGGQRLAQVSLTEAHLELVLRRSGADIEVQVASLSRPARLLRPALRLDAEELVEAARACGHGFLEDLKQVAPERLRDEQGQALKQALKELEESAPHPRELRPEPFTFRATAPTLPGFGFVLDDGDDVLRRAAREKGPALASLLCPGEVWLALPQRPVAWRAPGPPFLTALELTRQAADLARAMEVGEPRFSFEPAGVRPELTLDLKAGEARLGGPPIALRAEELLAAMFHLGQALALAMSERERSLANNPYLQELTERSREGLSHLRGAVRPPEEAGAAPARVATASGGSRPLKVPGRLRRLRFESLWEQRKLVDADMGRLMMGRQGLVYSSPDMACAFDRKTGKQVWRRAASHGVAASEDGYSLAASAVRLCGFPGKGSGADWLRVHDGLHVGPLLLRQYGMLYTLADERVVLALNEVTGREAWRLTPARTRRGYLSIHAHRALLATDSGYLYGLGLGDGQVRFRMSASLPFLGAPVPWARRFVALLGQGSNSALLLADAHTGEAVWTYEMSLALPSTPLPSGKRVYIAGELEGEGVLLCVDAAGQSRWQRALHLGPGPFALARLPGAVLVTSALGAAARVSDSGEVDWRVGASGEQLTRPLRPIVSRGVALVPGERVRAVDPLRGDVLAEVRAGAGLMALQADAQLNLYFLDELGTLSAYRLGSHFTVVGG
>NZ_CP022098.1|WP_095986578.1|4705671_4706577_+|hypothetical-protein
MKRYFGVIVLIVGIILAAVVTTRASSARALEAQRDADFARVQKDYLERVGWLRVNPDEKAYRQEVSSFFKAYFTQVDAHHDRYKLGKTYDAYLAELEKRGDKDDRVQDRKAFYEYTRQVFDQMREGKYEPLWTATDKGMRLDVVSADVVKVLDKPQVRLRLALWGAQREERSDGKVKKMVTSASFKTQWKLTDERGRLQGEMSAEDPSMKVDFPERFIAEFPPQMVLGHYDMDLVPNEVKKMEISFQVSSRAASGGDATASYVWKLEVPSEWRLGAGEKWEGAEVTERPEEEIDPAKAARK
>NZ_CP022098.1|WP_095986577.1|4704598_4705615_-|alpha/beta-fold-hydrolase
MYQTHGSYVSPVALPLEEGGLLGAARIAWCAYGERSEDNVVVLLHDLPHSHHALRPAGQDAVPYSGWGSELLGEGRPLDTAALHVVVPNLLGSPFGSTSPVAVDPHARRPYGAALPTVTVLDMARAVAALLRSMKVERVRAVVGVGLGGLVALRLAALFAERVGGVAVLGAARTLPESLRERLGLTRHLLRLDPDFHDGHYAPGAGPRRTLRKQALEYLRLVHGPGGEAPDATQALEAEAQALADTFDANAWALLCTAYAGADLSECLAEVRAPVLLAAAANDLLAPPARVRDTYHLLSAAGIRAHYHELPEPCSHQGLLAGSRRLHGPLRDFVRRRG
>NZ_CP022098.1|WP_095986587.1|4718959_4719790_-|transmembrane-regulator-PrtR
MTCQEFESILYPYLDGEFQPEERVTAEAHLRGCSTCASRVHEEGLLRQSLRRAARHSVETSRAPAALRSRLQANLHQEQRRAAQAAWLRMGAAALVLVTVSGVTWRALRPEHRQRYMEDAVRRHTKKLPVEIVGVSHENVEAWFDGKLDHRVSVPRLHDVRLSGARISNVTDRPAAYISYERNAEGQGGPARRIGVFVFDDARREVEAPTLPAVQVGSSLGYNVAMWRDGEIVYELVSDLNEADIRRMLAEQSAQKAASASPTTPSVPVLPVSLHP
>NZ_CP022098.1|WP_002626150.1|4719859_4720516_-|sigma-70-family-RNA-polymerase-sigma-factor
MLDFRQNNRTKQEFEELALAHLDPLYSAALRLTKNERDAEDLVQDTCMRAYRFFDKFERGTNIKAWLFKILTNTFINRYRRKVKERSVVEGVEREAVHERFVSRDATDFAANPEQYFFDRLLSDDVLRAIDALPIDFRLVVILADLQEFSYKEIAEILECPVGTVMSRLFRGRKLLQKTLKEYAEGTGVLRQEAGGEPVNLENATASLDEYRRRKKVG
>NZ_CP022098.1|WP_095986588.1|4720724_4721861_-|alanine-dehydrogenase
MIVGVPKEIKTREYRVGMVPAGVRALTSAGHTVLVETNAGGGSGIPDSEYQRVGAQIVQTADEVWKRAEMIVKVKEPIAPEYERIQDGQIIYTYFHLAGVDPELTRTLVKKRASAVAYETIQLDDGSLPLLKPMSEVAGKMAIQVGAACLEKAHGGKGILLGGVPGVRRGRVVVLGGGVVGTCAAKVAVGMGAEVTLIDINLERLTYLDDVFLGRVATLASDSESISRSVREADLVIGGVLIPGGKAPKLVSEALIAEMTPGSVVVDVAVDQGGCIETCVPTTHDNPTFVKHGVVHYCVANMPGAVPQTSTFALTNTTRPYARKIADLGLVEAIKSDKALARGLNTYNGHVTYETVAKDLGYSYLSIFDAIGAKGAAK
>NZ_CP022098.1|WP_095986589.1|4721996_4723301_+|radical-SAM-protein
MTQAPKLLFADPKGRVMEHPYLLATLRSGEELVPPQDKPIALPAAGRLVHLPGRLPVGLHPETGELELVREMKLEGKTFVPSAVGALLPPGYTRTFLPGEVKASGPVLPQWAYTAAAWGEDGPVAWAIHTDKRSHWDPERYSTPELKKLVDAHLARFPGNRVLKQLTTCAMLYRCFTSQNIFYVRDEGAIPASVMCNARCVGCISDQPADGPPASHERMDDGPSAEEMGAIGLHHLEHAPGRTMVSFGQGCEGEPLTRWKFIAESIRYMRAHTSRGSININTNASLTHGLEALFDAGLDAIRVSLNSAVKDLYEAYYKPVKYGWEDVEASIALARERGAYLALNLLLFPGVTDREGEVQALAKLVKKYKVDQVQTRSLCIDPIQYLEVARDKGAGGEPVGIRELLRRLKAARPGLVIGNFARGLDERQGRRDRG
>NZ_CP022098.1|WP_095986590.1|4723310_4724759_+|amidase
MQELAFLPAHEMAERVRLREVSAVELLEAHLQQVARNNVRLNALVTLDEARARARAREADEALARGEVWGPLHGVPLTIKDAFETTGLRTTSGFERLVDYVPQRDATVVARLKAAGAVVVGKTNLPRLALDTQTHNAVFGRTNNPWDVERTPGGSSGGGAVAVAAGMSPLEVGSDIGGSIRIPSHYCGVFGLKPTDGRVPLSGHIPGLPGTPRGVRHQGVAGPLARTVADLRLALRILSGPDGLDTEMPPVPFQEVPRRELRSYRFVWTDDFGGMPVSAQTRAALAGLARTLEGAGCVVERRTPEIDFDAVWTAWGQLLGAEVGAEIPLPARVMTALHFRSMRGDSAINRGIIRGLWGRMADYVQALSVRDQMMAKVEDFLAGWDAWLCPVTMGAAFTHRPSGEWVEVDARRVPYMEGTCGFSNFFNLTGHPVVAMPLPPESGRTLPLGVQVVGRRWKDEALLSVAEALTEVAGPFRRPPGV
>NZ_CP022098.1|WP_002632097.1|4726434_4726917_+|Positive-regulator-of-CheA-protein-activity-(CheW)
MAPDRAIAAQARPEQEFFCFRVADLRLAVPSENVLEVIRTGLLTPLPRTPSFLLGVTGHRGEVMPVMDLLRFLGKGEARVGPRTRLFIGTSGNYRVGVVADAVLGLRRIPVADILPPPLGGDAAAEHLIGVAEGLVPNETVALLHFTKLLQSARQRAVLR
>NZ_CP022098.1|WP_095986591.1|4726913_4727306_+|Frizzy-aggregation-protein-FrzB
MISEVFAPSEEEVDILFFEVGDIVYGTDASQVLRIERSLAEDLCLPELGPLKRGHRALVFDAPEGEGHLKVDAIRGVRPVPIHHLRRLPPVVGAAPYAVGVFLDDARPVMLIDLLETLMFKEGTEGNVAR
>NZ_CP022098.1|WP_095986592.1|4727292_4728513_+|methyl-accepting-chemotaxis-protein
MSLADSKNDFSATDGAARSKKAGSLKPITDTVIAVLAGNLEARVHKNALDEDAADLANLFNQLLERFAVSEHRKQVAAQEIDQAVDALISLGRDGDLARWNTTTEDAQLAPLLEGFGKVIETLRTFVREINEAALRLSSSSNQVLSASTQHETSSTEQAAAIHETTATMEELKHASAQIAENAGSVARVAEETLGAARAGRGAIGEFIQAMQQIRSDGVAVADSITKLSKRVERIGTVVEVIDEIADRSDLLALNAALEGSRAGEAGKGFSIVAAEMRRLAENVMESTKEIKNLITEIREATAAAGTAAEASKEATESGEKLGAVAAQAVEGILAGVQETSDAARVINLATQQQRTATEQVVASMAEIEDVTRQTTSASKQATGAAAELNQLAGRLAELIKRFKAD
>NZ_CP022098.1|WP_095986593.1|4728575_4730870_+|hybrid-sensor-histidine-kinase/response-regulator
MDTESLKRSLLQKFQEVSADRLQKIQLGVLDLEKPTADQAADEVARELHTMKGEARMLGLAAIGQLAHAAEDVLRAEREGKAATEVATDLLLRACDTIADLLEDHEGAQVGTLASQEMCEALSAASGHPIPPIGGVKAPSSTSVPAVRPAHAETVLEVMAEAVEPAYAPPPAPVAAAPAAAAAPRAAKAEHEEPHHNKLADRSIRVNVEVLDSLGLLAGDLLVESARGRLRASQIESLLQRFSRLGDRFLRLTEQLEVPNTLRNDVERIEGDLHMLRDDAFRFVRSNGDGIETLHGNLAMMADHVAEARLVPLSTVFDAFPRAVRDLSRSQAKEVDLVIENADLGVDRSMLADVRDALVHLLRNGVDHGLETPDERRMLGKPAAGRLRIRVRADGDMLSIEVDDDGRGMDPQKLRAVAVRKHLLTENQAASLSEREAIELIFRPGFSTREEVTDISGRGVGMDVVKKKVESLGGSVGISSRLGRGSTFTLRLPQSLALMKVLLVRLGDDVYGIPAADVVAVMRVKPDDRMEVFGTLAVKHRGKPIALVGLGPLLGVNGGNRFDKPPAVVVRHGDDHAALVVDGFVDEREVAVKPCGGEFLKGAAFIAGTAALEDGRIAVLLHVPDIMTEVRRMARPVTQGTTAKRLKVLLVDDSPIARATESALVKALGHTVDEAQDGEEGYLRAQSQTYDLILTDVQMPRLDGFSFTRRLKSTAGLARTPVIVLSSLASPEDRRRGAEAGADAYLVKGELGVESLAQTIDRLT
>NZ_CP022098.1|WP_095986594.1|4730916_4731897_+|chemotaxis-response-regulator-protein-glutamate-methylesterase
MLLVGEVFRGASRGLFDGSVLAPSGNVCGFAEALEGVQRLHPDVVVVDLAAPESLQAIARVMVERPVPVLALHPGVLSDAEAFQALASGAVEVVSRPAEPGAEFWHTVSRKLMLLAEVRVSRPVQGQSKPVRPAPSEAPYPLVAIASSLGGPKALSVLLKTLPQDFPAPVCICQHISEGFTEGLAQWLGASSSLRVVEASEGDAMVPGSVYIAPSGSHLLVRSGGLLSLDPGPPVRGFRPSCDVLLTSAAESFGTRVLGVILTGMGRDGARGLKEIRERGGRTIAQDKATCAVYGMPKEAVRLGAAEEVLPLDRIGPTLTQWVRTC

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_14

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_14

4992956-4993088

Orphan

Consensus_repeat	Method
CGCCCGTGGCGGAAGTAGCCCCCGT	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP022098_14

>merge|NZ_CP022098|14|4992956-4993088|CRISPRCasFinder
CGTCCGCGGCGGAGGCCGCTCCGGTGGTGACGGCGGCCCCGATGGCCTCGGCCGCGCCCGTGGCGGAAGTAGCCCCCGTTGCCGAGACCGTGCCGGAGCAGGTGTCCACGCCCGTGGCGGAAGTGGCCCCCGT

>NZ_CP022098|14|14|4992956-4993088|CRISPRCasFinder
CGTCCGCGGCGGAGGCCGCTCCGGT	GGTGACGGCGGCCCCGATGGCCTCGGCCG
CGCCCGTGGCGGAAGTAGCCCCCGT	TGCCGAGACCGTGCCGGAGCAGGTGTCCA
CGCCCGTGGCGGAAGTGGCCCCCGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_095992132.1\|4981946_4982672_+\|transglycosylase-SLT-domain-containing-protein	unknown	unknown	gnl\|CDD\|381605
NZ_CP022098.1\|WP_157758547.1\|4987164_4989285_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237855
NZ_CP022098.1\|WP_095986768.1\|4995092_4995419_+\|quaternary-ammonium-compound-efflux-SMR-transporter-SugE	unknown	unknown	gnl\|CDD\|171110
NZ_CP022098.1\|WP_095992134.1\|4991647_4992583_+\|P-loop-NTPase	unknown	unknown	gnl\|CDD\|349758
NZ_CP022098.1\|WP_095986775.1\|5004927_5005893_-\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635
NZ_CP022098.1\|WP_095986770.1\|4996449_4998300_-\|DUF885-domain-containing-protein	unknown	unknown	gnl\|CDD\|377577
NZ_CP022098.1\|WP_095986767.1\|4994126_4995074_+\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|161659
NZ_CP022098.1\|WP_002627508.1\|4993869_4994133_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095986760.1\|4982844_4983630_+\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
NZ_CP022098.1\|WP_095992133.1\|4983644_4984730_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|282094
NZ_CP022098.1\|WP_095986762.1\|4985631_4986831_-\|DUF2403-domain-containing-lipoprotein	unknown	unknown	gnl\|CDD\|370949
NZ_CP022098.1\|WP_095986765.1\|4990862_4991462_+\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|372995
NZ_CP022098.1\|WP_095986764.1\|4989471_4990869_+\|L-seryl-tRNA(Sec)-selenium-transferase	unknown	unknown	gnl\|CDD\|273099
NZ_CP022098.1\|WP_095986761.1\|4984722_4985565_-\|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|143393
NZ_CP022098.1\|WP_095986759.1\|4981116_4981542_-\|OsmC-family-protein	unknown	unknown	gnl\|CDD\|274650
NZ_CP022098.1\|WP_095986772.1\|4999713_5001477_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224490
NZ_CP022098.1\|WP_095986769.1\|4995429_4996446_+\|NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|225915
NZ_CP022098.1\|WP_095986774.1\|5002900_5004931_-\|DUF3488-domain-containing-protein	unknown	unknown	gnl\|CDD\|376628
NZ_CP022098.1\|WP_095986771.1\|4998392_4999712_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225116
NZ_CP022098.1\|WP_095986773.1\|5001650_5002550_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|235838

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095992132.1\|4981946_4982672_+\|transglycosylase-SLT-domain-containing-protein	gnl\|CDD\|381605	cd13402, LT_TF-like, lytic transglycosylase-like domain of tail fiber-like proteins and similar domains. These tail fiber-like proteins are multi-domain proteins that include a lytic transglycosylase (LT) domain. Members of the LT family include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, and the eukaryotic "goose-type" lysozymes (goose egg-white lysozyme; GEWL). LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.	8.53855e-42
NZ_CP022098.1\|WP_157758547.1\|4987164_4989285_+\|hypothetical-protein	gnl\|CDD\|237855	PRK14900, valS, valyl-tRNA synthetase; Provisional.	9.19887e-05
NZ_CP022098.1\|WP_095986775.1\|5004927_5005893_-\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	5.97742e-19
NZ_CP022098.1\|WP_095992134.1\|4991647_4992583_+\|P-loop-NTPase	gnl\|CDD\|349758	cd02038, FlhG-like, MinD-like ATPase FlhG. FlhG is a member of the SIMIBI superfamily. FlhG (also known as YlxH) is a major determinant for a variety of flagellation patterns. It effects location and number of bacterial flagella during C-ring assembly.	1.02651e-61
NZ_CP022098.1\|WP_095986770.1\|4996449_4998300_-\|DUF885-domain-containing-protein	gnl\|CDD\|377577	pfam05960, DUF885, Bacterial protein of unknown function (DUF885). This family consists of several hypothetical bacterial proteins several of which are putative membrane proteins.	0
NZ_CP022098.1\|WP_095986768.1\|4995092_4995419_+\|quaternary-ammonium-compound-efflux-SMR-transporter-SugE	gnl\|CDD\|171110	PRK11431, PRK11431, quaternary ammonium compound efflux SMR transporter SugE.	1.58227e-31
NZ_CP022098.1\|WP_095986771.1\|4998392_4999712_-\|hypothetical-protein	gnl\|CDD\|225116	COG2206, COG2206, c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms].	3.51396e-29
NZ_CP022098.1\|WP_095986760.1\|4982844_4983630_+\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	9.58193e-76
NZ_CP022098.1\|WP_095986762.1\|4985631_4986831_-\|DUF2403-domain-containing-lipoprotein	gnl\|CDD\|370949	pfam10287, DUF2401, Putative TOS1-like glycosyl hydrolase (DUF2401). This family of proteins is conserved in fungi. One member is annotated putatively as OPEL, a house-keeping protein, but this could not be confirmed. It contains 5 highly conserved cysteines two of which form a characteristic CGC sequence motif. It has recently been shown that this family is related to known glycosyl hydrolases.	1.4278e-80
NZ_CP022098.1\|WP_095992133.1\|4983644_4984730_+\|hypothetical-protein	gnl\|CDD\|282094	pfam04188, Mannosyl_trans2, Mannosyltransferase (PIG-V). This is a family of eukaryotic ER membrane proteins that are involved in the synthesis of glycosylphosphatidylinositol (GPI), a glycolipid that anchors many proteins to the eukaryotic cell surface. Proteins in this family are involved in transferring the second mannose in the biosynthetic pathway of GPI.	1.18172e-05
NZ_CP022098.1\|WP_095986767.1\|4994126_4995074_+\|RluA-family-pseudouridine-synthase	gnl\|CDD\|161659	TIGR00005, Ribosomal_large_subunit_pseudouridine_synthase_D, pseudouridine synthase, RluA family. In E. coli, RluD (SfhB) modifies uridine to pseudouridine at 23S RNA U1911, 1915, and 1917, RluC modifies 955, 2504 and 2580, and RluA modifies U746 and tRNA U32. An additional homolog from E. coli outside this family, TruC (SP\|Q46918), modifies uracil-65 in transfer RNAs to pseudouridine. [Protein synthesis, tRNA and rRNA base modification].	8.63552e-109
NZ_CP022098.1\|WP_095986765.1\|4990862_4991462_+\|HNH-endonuclease	gnl\|CDD\|372995	pfam14279, HNH_5, HNH endonuclease. This domain is related to other HNH domain families such as pfam01844. Suggesting that these proteins have a nucleic acid cleaving function.	3.41682e-17
NZ_CP022098.1\|WP_095986764.1\|4989471_4990869_+\|L-seryl-tRNA(Sec)-selenium-transferase	gnl\|CDD\|273099	TIGR00474, selA, L-seryl-tRNA(Sec) selenium transferase. In bacteria, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements: SelC is the tRNA itself, SelD acts as a donor of reduced selenium, SelA modifies a serine residue on SelC into selenocysteine, and SelB is a selenocysteine-specific translation elongation factor. 3-prime or 5-prime non-coding elements of mRNA have been found as probable structures for directing selenocysteine incorporation. This model describes SelA. This model excludes homologs that appear to differ in function from Frankia alni, Helicobacter pylori, Methanococcus jannaschii and other archaea, and so on. [Protein synthesis, tRNA aminoacylation].	0
NZ_CP022098.1\|WP_095986761.1\|4984722_4985565_-\|nucleotidyltransferase-domain-containing-protein	gnl\|CDD\|143393	cd05403, NT_KNTase_like, Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins. S. aureus KNTase is a plasmid encoded enzyme which confers resistance to a wide range of aminoglycoside antibiotics which have a 4'- or 4''-hydroxyl group in the equatorial position, such as kanamycin A. This enzyme transfers a nucleoside monophosphate group from a nucleotide (ATP,GTP, or UTP) to the 4'-hydroxyl group of kanamycin A. This enzyme is a homodimer, having two NT active sites. The nucleotide and antibiotic binding sites of each active site include residues from each monomer. Included in this subgroup is Escherichia coli AadA5 which confers resistance to the antibiotic spectinomycin and is a putative aminoglycoside-3'-adenylyltransferase. It is part of the aadA5 cassette of a class 1 integron. This subgroup also includes Haemophilus influenzae HI0073 which forms a 2:2 heterotetramer with an unrelated protein HI0074. Structurally HI0074 is related to the substrate-binding domain of S. aureus KNTase. The genes encoding HI0073 and HI0074 form an operon. Little is known about the substrate specificity or function of two-component NTs. The characterized members of this subgroup may not be representive of the function of this subgroup. This subgroup belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, co-ordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are conserved in this subgroup.	6.34544e-07
NZ_CP022098.1\|WP_095986759.1\|4981116_4981542_-\|OsmC-family-protein	gnl\|CDD\|274650	TIGR03562, osmo_induc_OsmC, peroxiredoxin, OsmC subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein OsmC, or osmotically induced protein C. The member from Thermus thermophilus was shown to have hydroperoxide peroxidase activity. In many species, this protein is induced by stress and helps resist oxidative stress. [Cellular processes, Detoxification].	3.1466e-59
NZ_CP022098.1\|WP_095986772.1\|4999713_5001477_-\|hypothetical-protein	gnl\|CDD\|224490	COG1574, COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only].	0.00212928
NZ_CP022098.1\|WP_095986769.1\|4995429_4996446_+\|NAD(P)-binding-protein	gnl\|CDD\|225915	COG3380, COG3380, Predicted NAD/FAD-dependent oxidoreductase [General function prediction only].	1.41417e-93
NZ_CP022098.1\|WP_095986774.1\|5002900_5004931_-\|DUF3488-domain-containing-protein	gnl\|CDD\|376628	pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine, and aspartate residues that form the catalytic triad in the structurally characterized transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologs of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.	2.86512e-26
NZ_CP022098.1\|WP_095986773.1\|5001650_5002550_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|235838	PRK06596, PRK06596, RNA polymerase factor sigma-32; Reviewed.	6.18565e-115

>NZ_CP022098.1|WP_095992134.1|4991647_4992583_+|P-loop-NTPase
MEPTGTARARPHRIIAVGGGKGGIGKSLVSSNLGVALAARGQRVLLVDADLGGANLHTCLGVGQPTATLSDFLLRPKSRLEDVIVPTGVPNLSLIAGALDVLDAANIKYAHKQRLLRSLQSQSVDYLILDLGAGSSFNTLDFFIIADHGVLVLLPEPTSVENAYRFVKAAFFRRLQQVEAEYGIERLVERALSTREGASRTPLEIVQHVRQQSPTLAAKLEKELAAFRVKLVLNQARTDADVKVNAAVVSAWKKFFGLEMDDFGAIRYDDEAWRAVRKRRPIVLDKPDSPSALGIQRIADRLLALDGVTSP
>NZ_CP022098.1|WP_095986765.1|4990862_4991462_+|HNH-endonuclease
MLNSAVLVLNRNYQPVHVTSVKRAVLLLYLGVAKAIDSQYRLYEFDDWAALSATTAHDSISTVDRRIRVPRVVVLSAYEYLPRGRVRFSRLNIYARDHDTCQYCARQLPRSELNLDHVMPRSQGGKTSWENVVCSCVPCNLRKGGRTPEQAAMKLLRTPVRPRWTPFFRGASRRVTYREWLPFLNLADASYWNVELLDD
>NZ_CP022098.1|WP_095986764.1|4989471_4990869_+|L-seryl-tRNA(Sec)-selenium-transferase
MGAPSTEDGGKNARLRALPSIEQLLRRPSLEARLAGVPRARAVAALRLAVASVRERLLQGEERAFEDADVDGALRALSTPNLRPVLNATGVVLHTNLGRAPLALEAVARVASVARGFCNLEYDLEEGERGSRYAPVVELLTQLTGAEDALVVNNCAGAALLMLAALASGREAIVSRGELVEIGGGFRVPDVMKQSGARLVEVGTTNRTRHSDYESALSPDTGVLMKVHRSNFALVGFTAEVEVKELAALGRARGVPVLVDLGSGALVSLPGEDFVHEPTVPATVAAGADVVAFSGDKLLGGPQAGILVGRAALLARIRQHPLTRALRVDKMTVSALEATLELYRDGRLEAIPTYRLLTTPAPVLEARARRLLSLLTPKGIHARVAPVSGQVGGGAMPAARLPSFACVLNFNQPAALLECLRKADVPVIGRISDGDVVLDVRCLAEEDLEPVAEAVAMASQGRQPC
>NZ_CP022098.1|WP_157758547.1|4987164_4989285_+|hypothetical-protein
MGSGSGRQSPGSQSPGAGADREARRIPGLVDRPLVKGEENDAHTRSVMRTRLLGEDTEINAVDQARREARLLGQMEHQGEAPTRIVSQLNEQLSGAQGSEFKSMLARELKPQLDRLAGQVDQATTENRRKIAAFISRAAHMAGSENAGTFDKMLAETASAEAKHLAAFSGAGVAERVSEFQAALRCAASPAYRATLVEKSRGHIERLARDAIRLPTNQFHDVLVLFLGTSEALGRVACNTMSKAFLAGALGPGSADAAGKLVKALGPALLEAPEGGNWAVRLMLNLAESGKHDVAAALGQSLQDIVQKARERCGPMLGAVQTAVDKGELLERSQKLDGHVSTLAELMPMCALLLAARNVVPGGGNGPLVTEALVAVASLDAVGTTDSGQRLLRQTLIAEELGEPSFLGIVPVAVRPLGHPRILQLLAECGLAAAHYRNGGSLFVQRVARQVFRALSGVVLARSQKGESEEARRLLGSALCHHAALYGMNSEGGQLTAELLERLRGNPDPEQAPRVLAELDGVARTHLSPYRTGHVESLRALVMALAERDPLAAPRSAGTRRRAGAAPVMKAMEMERTHIVQMKKLRAEREAAMAARESSAKPSPEKASSVKAPPAKTPATKAPATKAPATKAPAMAAEAPPAEPPPPAERKPVDDERWREGTNARYLERTHNFQMMRRQPRRQDPDEETAPAPLEPPAPGSPRFRG
>NZ_CP022098.1|WP_095986762.1|4985631_4986831_-|DUF2403-domain-containing-lipoprotein
MKNPWMKRGPWLAPLALCVLLGTACGNTQTSEEPGSGQTGTDHPSEGSGGGGGGGDQPIQASDCAAGQAAALEDLGDDLPEGTGTPVTTMSILNVGGTGSYQRVTNMLPGVWGQPCPSNACQKADTPVSGPLAPFNEEMTVNFRGPMELYDIAVYQPGASAWNRVSSWNRCGSTNLTFFNNLGGGDVSGEWTVCGGNSQSYASADGKTAAKAPTRFNGTLANRTELNILSDKACVGTGDSSECGFYRGVTRHGWGGAKIFAIRARMPRYTEPKTQYYDDVPAIWMLNARVVRTAQYGCNCRGMGSPGGCGELDVAEVIHGENPLYATSTIYSFEGATGSGSKYFQRPVKESATFIVIFDASGKIQMLRLAADAFNFGDTVSNTTVSEWLARTGLKMSLP
>NZ_CP022098.1|WP_095986761.1|4984722_4985565_-|nucleotidyltransferase-domain-containing-protein
MEDPILVRVVDALRSVPGVAALVLGGSRGRGTAGPTSDYDIGLYYEPDAPLDVAALRSAIAPLVDDPSSTVTSIGEWGPWINGGGWLTIAGVEVDLLYRDLGRVREVIAEGRQGRFSMNYQVGHPHGFCSVIWMGEVATCQPLLDPLGLIAELKGQTRPYPEPLRDALIARFGWEVGFAIDNAEIAARRSEQTHIAGCAYRALSCVAQVLFALNGRYLINEKGAVPEAATYPLTLEGLSKTQAEIWSDIGNADHASALRRLRGVSDGLRALVERAGMKAS
>NZ_CP022098.1|WP_095992133.1|4983644_4984730_+|hypothetical-protein
MREWGARIAFPVGLFVFSRLALLLLARVSLVLETRLYRPPFKYPGLAGLEAFCWWDCGWYTGIAQEGYTRAQATNFFPLLPLLGRMVHELTGLSIPVALVGIAQVAGLLALVVLHQLFRELADEEEARTALLLFTAYPFAFFHSAGYPESLMVLLTALAVALSLRGRHGWAGLTLGVAGLARHLSLLAGFSLLYQQLRSRGGGVRALLHRDVLALLLPPLITSLYFVYLWRTFGDPQLWWKVRAQGWGGAWAGLGDWLRGKWAPEVGLYVGVSFIPGVGALLLLRQRQWWVLAAFALPLMLVLWTVGLVGLGRYSAAVWPAFLPLGAWLARRPALRDPIILGCALFQGMLVYFFVHSYPIN
>NZ_CP022098.1|WP_095986760.1|4982844_4983630_+|DeoR/GlpR-transcriptional-regulator
MPPPDSSATAHLPEERRRIILERLATEGRVFAADLCGILRVSEDTIRRDLRELDEAGLLRRVHGGALPRAQAPLAHTVRAEARQSEKQALARIAAGLVRADQVLFLDGGTTMLEVARCLPRELRGTVVTVSPPVALALAEHPGLEVRLVGGRVHPQALTLVGAETVEALRQVRADLFLLGVCGLHAEAGITALHAEEAAVKRAMIQGAAETVAVVTADKLGTLAPFVVAPVQALAALVTETPASESTLAPFRKLNLRVMTP
>NZ_CP022098.1|WP_095992132.1|4981946_4982672_+|transglycosylase-SLT-domain-containing-protein
MKFPETPSFASTPTETLPELDPSQLLNLFADAFSTEPTPSSFSDPTGQGGGLDQLLEQAKQLVQTLEQLTELLQAPEIGEEPPAGGKQPQSLFQNPEGPGAPEGGPGGPEGTSGTQGAGEAPKGQVGDWIKEAQKQLAAAGIPADKMKAEDIAKIIQHESSGDPNAINLWDDNAKKGTPSIGLMQTIQPTFDAYKLPGHDNIRNPVDNIIAGVRYAVDRYGSVSNVPGLQAMNNGSGYVGY
>NZ_CP022098.1|WP_095986759.1|4981116_4981542_-|OsmC-family-protein
MGISKGSAQWNGGLKDGQGVMKPAHAPEAPFSLGTRFEGKQGSNPEELIGAALSGCFSMALSLGLETAGLKPTSIKTSADVQLDKQGAGFAITTIALTTEAIVPGASDEQFQKIAEETKKGCPVSKALAGTTITLKASLAR
>NZ_CP022098.1|WP_002627508.1|4993869_4994133_+|hypothetical-protein
MTEEEKIKAMRLARAIASDISLYNEQKIIKGIEQDNLFEVLKEELEEGRELYKSRVSPEIFQRMNFFERAINDIVLRSKAHVKSKIW
>NZ_CP022098.1|WP_095986767.1|4994126_4995074_+|RluA-family-pseudouridine-synthase
MVGPAVREQLAPPEARGERLDQVLARVFPEFTRSRLQGLIESGHARVDGKPAKVSLRLKGGERLTLEVPAPTPALPVAEELPLAVLREDKDLVVVDKAAGMVVHPGAGHASGTLVNALLHRVKDLAGVGGELRPGIVHRLDKDTTGCLVVAKHETALVALQKAFKTRTVEKTYLALVHGSPKAAEGRIETLYGRHPVHRQRFTGKVKEGKPALTVYRVLESFEGAALVEVDLLTGRTHQIRVHLAELGHPLLGDALYGAGRKPKGLAGAAQDVVGRQALHAWKLSFPHPRTGKVLRVEAPLPPDFTAALEVLRGR
>NZ_CP022098.1|WP_095986768.1|4995092_4995419_+|quaternary-ammonium-compound-efflux-SMR-transporter-SugE
MAWVMLVIAGLFEVGWSIGLKYTEGFTRLTPTLLTLVALAASMVLLSLAARTLPIGTAYAVWVGIGALGAAVLGILLFHEPVTPARVFFLALLLVAIIGLKITGGAGH
>NZ_CP022098.1|WP_095986769.1|4995429_4996446_+|NAD(P)-binding-protein
MASSSSSDLSTSRFPRVAVIGAGLAGLTLARILTEMGLSVNVFDKGRSPAGRMSTRHEAGGSFDHGAQYFTARDEGFQRQVETWVEQGIAAEWRGRFGTLENGTLTPKDEGPVRYVGVPGMSALAQAFASRVDVRCGVRVEHVRREHEAWALTSDTGEALGAFHAVVAAVPAPQAVPLLAGSPELSARVAGVRMEPCWSVMAGFAAPVPLPVDGAFIHGSPLSWASRDNSKPGRPEGERWVLHATPDFSREHLEDSPEAVAPLLVEAFSRAAGVDVRPVRTVAHRWRYAQAESPLTEGALFDDKRGLGACGDWCAGSRVEGAYLSAMALSRRIVFWRP
>NZ_CP022098.1|WP_095986770.1|4996449_4998300_-|DUF885-domain-containing-protein
MPSSRFLAPLLLVLSLGACATPSATLSSPPPSADAKTGGDADQRLLTFLDAAYEERLALSPEGLTYQGSKQSYDRLDDHTEAGARKQQELAEQQLARMKREFDERALSPASRLSYRLFEDLVVRGRERLRWYSHGFPVTNSSNPTSNIPVFLINAHRVGSVSDARAYVSRLREVPRVMKEISERMRAQAARGIVPPRFVFAPVEADARRVLSGAPFDTGADSAVWADFQKKVGALEAPADEKARLLDEAREALKGPFKSGYEMLLATLAEVERQAKGNDGAWSLPDGAAYYADQLRFFTTTEMTPEEIHAAGLAEVERIHREMEVIQKQVGFQGSLQDFFAHVKADARSHHPNTEEGKQAYLADARRFIAQAMKEAPRLFHRLPRAALEVRAVESWRQETAPVAFYNLPAPDGSRPGIYYVNLADMNQVLKPQIEGITYHEGAPGHHFQIAFAQELEGLPKFRRFGYHGAYTEGWGLYAEKLGQELGFYADPYSRFGQLSLELWRAVRLVTDSGMHAKRWSREQAIEYFKKNTLLSDRDIVKEVERYLVWPGQATSYKVGELRLLALRARAQEALGPGFDVRDFHQVVLGNGSLPLDVLGEQVEAYIAAKRAPAAR
>NZ_CP022098.1|WP_095986771.1|4998392_4999712_-|hypothetical-protein
MAENLKVTHGAQGQAENLSEVGRAYSEKLQTLARGLISGLYMLIRSVKMYDPENSVFEKPLLQLQDIINQIISKEGRLELVGVKESYYLNNMLVKVDLNSIDNQRYLLAEMRSKDVGGISLTKVITVQELKNFIWIFSKEQLASADEDGLADRKLLNMKVAKFSRLREKLSREEDGKQDQKVDRKKYAMTVYARAVFFLTRYLESVQAGKPLNTSRALRLVQDFVDISFEQRTHFLGMTTMKREMDYLVYHQVNVCLMSIVFGQELGLTKPQLRDLGYIALFHDAGMATIPEELATKRGALSAEEKAIIQKAPLISIRNILMEKGFSRSTLLRVVTTFEHKADFGTAVRDARGDIQMIIPKTNLGTYAKIIAICAAYDALTSKRPYRDAYGPEVALMLMWTEMRNKFDPELLQVFMRVMAIQPVKVLSRRQQSMTLGGL
>NZ_CP022098.1|WP_095986772.1|4999713_5001477_-|hypothetical-protein
MDQVQPGNSPSTEPVMDPSVQDKVESARAVAAQLLKGIKQIGMYRHNEAKFPEFLARTHEALTAHTEKHGALLIKVEQQNFMTYGEPLFAEDTPLPYKFFRDGIRQLILRPGLSIEELVTFTLIALSEPERGAEDVLAQLWRSGLEHLEYVVVEGFRMDEVSDEEVEVEVDRVVGYLYSRLKTSSDDYLRFARVNAEDLDSKMDGVEQMRGLVVAGNYASDDLKARLQREISEEEGARLFPKLVSAIFLVIEGGVEDRELLEEIFVQLLDAMLIQDDYGTINQMLLKMRALAQRAPGGEIERLVGYFTQKMGDEQRVMRLAEMLKATRPRNPVDINRYVQALDSSAVFALLNALETIDIPENRLLMCDALARFAQDNPHPFVQRLESERPQTVRDMVYILEKSDHPERVRMFGLVMLNKNLAVKLEVMNIIARGRTTEARKLIIDALNDPATQVRMLAARLLPEFDRDRAYTDLMRLMREASFDKKSLEERTAYYSALGSTALPGAISLMLQTLSVKPTLLNKKKVLEDKLLAVAGLAAACSIPGYKALQGVVEDKTQPLEVLTAARKAMYQTKKTLFGETTASEEA
>NZ_CP022098.1|WP_095986773.1|5001650_5002550_-|sigma-70-family-RNA-polymerase-sigma-factor
MQLSTEQSSNSGSLAMYLSEINQYALLKVEEEQALARGFLQGDFAAGHKLVTSNLRFVVKVAYEYRSYGIKMSDLIQEGNIGLMKAVQKFDPDKGIRLISYAVWWIRAYIQNYILKSWSLVKLGTTQAQRKLFFSLARTRRELEKFGTLDGSVVNVEEIARKLNVKATEVREMEQRMGGRDLSLDAPMGEEGGNSHVDFVASDSTSQDDEFADREEAGLINTRVRTALMRLDPRERFIIEQRVMNERPMTLKELGEHFGFSRERARQLEIRAKDKLKAELAALMAEVDPDSTEASAQQQ
>NZ_CP022098.1|WP_095986774.1|5002900_5004931_-|DUF3488-domain-containing-protein
MRQPLRLRLVLRDLSTAAAFASMAISSQVPVWALVLFALALIVALTGRRPLARAPRLTALLLLPVAGLLYLAVASGQMDLVVAACSFAGIVAAQRLLSESTAATDGQVLLVGLLMIAGGAALSGELVFALCLLAFAVLASLSLGLAVVEAAVPPGEPVPVRAVMRPLARGTFVAVVGAALFFILIPRLSWNMGVRRASPGLGTATSGFSDTVRLGGSGTLKSNPRVVLRARLTPDPVDTEHLSAYWVGRTYDTFDGQEWSTIGAAKQRHRTRVTLRPGADKQVYQRIELLPAYGSRTLIALETPAKLGNALTHTPTGDRRTRLQELGGDELRFVDDGLGYSYEVYSLPPGTDTDPGRMNQTEADQLLALPENLDPRVEQLARRVVGDEKDPLAAAQKLSAWLQREYQYTLELSGDLADPLEDFLFVRKAGHCEHFATALTLMLRTLGFESRLATGFFGGERVGEEYIVRAGDAHAWTHVLVPGRGFITVDATPPAFRTNQSIQILESLVSLYEAIEGVWRTSVVDYSFRDQLDFMRGLSRPPRDPSSDEQRPSGPPARAWWTAGLVALGVYGLVRYLSRRPRRSPLGEATRLVDAVERQLTRAGLPPREGETLEDVSARFTRDAHPLGPTLAPLTRRYLEARFGQRPLESGERARMLEDLRRALDTWRQGSRSNAP
>NZ_CP022098.1|WP_095986775.1|5004927_5005893_-|DUF58-domain-containing-protein
MSPSRPPSPWRRLRARLRPPRTLKVTGMGRTYLVVTFGVGLGALNTGNNLLYLVLGLLLSVIILSGVLSERCLRDLSVRRVGNEGAFAGEPFAFRWALTRRQGHAFALTLSEVDVPLTGEGGVGHLPAGAEHVVRADLTAPRRGPVKLVGVRVTTTWPLGLFAKTRVFPLPGTLLVFPRRGFACATPEDAATGHVGEAHHPHRLDGTGDLAGLRELGEGEDARRVHWLKSASAGKLLKVEREREERRTYVLEVRAGLADEALERRCEEVAEQAHRLLEAGHEVGLELPGQRLRPGAGSGQERLLLRALAWVGFEEQREEAA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_15

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_15

5454171-5454337

Orphan

Consensus_repeat	Method
CCGCCTCCGGGCATGGCGCGGCCGGG	CRT

3 spacers

The CRISPR arrays of NZ_CP022098_15

>merge|NZ_CP022098|15|5454171-5454337|CRT
CCGCTTCCGGGCATGGCGCGGCCGGGTGGTCCTCCGGGACCGGGCGCTCCGCCTCCGGGCATGACGCGGCCGGGTATGCCGGGCCCTGGGGCGCCGCCTCCGGGCATGGCGCGGCCGGGCGGTCCTCCGGGACCGGGCGCTCCGCCTCCGGGCATGGCCGGCGGTCT

>NZ_CP022098|15|1|5454171-5454337|CRT
CCGCTTCCGGGCATGGCGCGGCCGGG	TGGTCCTCCGGGACCGGGCGCT
CCGCCTCCGGGCATGACGCGGCCGGG	TATGCCGGGCCCTGGGGCG
CCGCCTCCGGGCATGGCGCGGCCGGG	CGGTCCTCCGGGACCGGGCGCT
CCGCCTCCGGGCATGGCCGGCGGTCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_095987048.1\|5459175_5460801_-\|alkaline-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|293740
NZ_CP022098.1\|WP_157758590.1\|5445978_5447064_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|240572
NZ_CP022098.1\|WP_095987047.1\|5454807_5458302_+\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NZ_CP022098.1\|WP_095987040.1\|5444869_5445202_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|259003
NZ_CP022098.1\|WP_071902205.1\|5463153_5463333_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_157758588.1\|5443541_5443955_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095992159.1\|5458362_5459169_+\|carboxylating-nicotinate-nucleotide-diphosphorylase	unknown	unknown	gnl\|CDD\|238806
NZ_CP022098.1\|WP_095987043.1\|5449409_5450966_-\|hybrid-histidine-protein-kinase/response-regulator-SinK	unknown	unknown	gnl\|CDD\|223715
NZ_CP022098.1\|WP_095987049.1\|5460897_5461299_+\|acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|223894
NZ_CP022098.1\|WP_095987045.1\|5452501_5453314_+\|defective-in-fruiting-DifE	unknown	unknown	gnl\|CDD\|366716
NZ_CP022098.1\|WP_095987044.1\|5451076_5452453_-\|diguanylate-cyclase	unknown	unknown	gnl\|CDD\|143635
NZ_CP022098.1\|WP_095987054.1\|5465821_5466631_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP022098.1\|WP_095987052.1\|5463363_5464425_-\|ADP-ribosylglycohydrolase-family-protein	unknown	unknown	gnl\|CDD\|377122
NZ_CP022098.1\|WP_095987051.1\|5462360_5462786_+\|cyclase	unknown	unknown	gnl\|CDD\|176861
NZ_CP022098.1\|WP_095987041.1\|5445523_5445865_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_043433682.1\|5447143_5447500_+\|response-regulator	unknown	unknown	gnl\|CDD\|381085
NZ_CP022098.1\|WP_095987050.1\|5461342_5462308_+\|class-II-fructose-bisphosphatase	unknown	unknown	gnl\|CDD\|236536
NZ_CP022098.1\|WP_095987053.1\|5464510_5465806_+\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP022098.1\|WP_095987042.1\|5447667_5449308_+\|chaperonin-GroEL	unknown	unknown	gnl\|CDD\|234573
NZ_CP022098.1\|WP_157758589.1\|5444420_5444807_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095987048.1\|5459175_5460801_-\|alkaline-phosphatase-family-protein	gnl\|CDD\|293740	cd16016, AP-SPAP, SPAP is a subclass of alkaline phosphatase (AP). Alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH. Alkaline phosphatase exists as a dimer, each monomer binding 2 zinc atoms and one magnesium atom, which are essential for enzymatic activity. Although SPAP is a subclass of alkaline phosphatase, SPAP has many differences from other APs: 1) the catalytic residue is a threonine instead of serine, 2) there is no binding pocket for the third metal ion, and 3) the arginine residue forming bidentate hydrogen bonding is deleted in SPAP. A lysine and an asparagine residue, recruited together for the first time into the active site, bind the substrate phosphoryl group in a manner not observed before in any other AP.	7.96316e-89
NZ_CP022098.1\|WP_157758590.1\|5445978_5447064_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|240572	cd12952, MMP_ACEL2062, Minimal MMP-like domain found in Acidothermus cellulolyticus hypothetical protein ACEL2062 and similar protein. The subfamily includes an uncharacterized protein from Acidothermus cellulolyticus (ACEL2062) and its homologs from bacteria. Although its biological role remains unclear, ACEL2062 contains a minimal metalloprotease (MMP)-like domain consisting of 3-stranded mixed 2-beta sheets and a HExxHxxGxxD/S (x could be any amino acid) motif. It may belong to a superfamily of bacterial zinc metallo-peptidases, which is characterized by a conserved HExxHxxGxxD motif.	1.13319e-30
NZ_CP022098.1\|WP_095987047.1\|5454807_5458302_+\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_CP022098.1\|WP_095987040.1\|5444869_5445202_-\|hypothetical-protein	gnl\|CDD\|259003	pfam14866, Toxin_38, Potassium channel toxin. This family includes scorpion potassium channel toxins.	0.000604953
NZ_CP022098.1\|WP_095992159.1\|5458362_5459169_+\|carboxylating-nicotinate-nucleotide-diphosphorylase	gnl\|CDD\|238806	cd01572, QPRTase, Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with 5-phosphoribosyl-1-pyrophosphate (PRPP) in the presence of Mg2+ to produce nicotinic acid mononucleotide (NAMN), pyrophosphate and carbon dioxide. QPRTase functions as a homodimer with two active sites, each formed by the C-terminal region of one subunit and the N-terminal region of the other.	2.64921e-124
NZ_CP022098.1\|WP_095987043.1\|5449409_5450966_-\|hybrid-histidine-protein-kinase/response-regulator-SinK	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.33382e-32
NZ_CP022098.1\|WP_095987049.1\|5460897_5461299_+\|acyl-CoA-thioesterase	gnl\|CDD\|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	3.83424e-42
NZ_CP022098.1\|WP_095987045.1\|5452501_5453314_+\|defective-in-fruiting-DifE	gnl\|CDD\|366716	pfam01584, CheW, CheW-like domain. CheW proteins are part of the chemotaxis signaling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and other related proteins that are involved in chemotaxis. The CheW-like regulatory domain in CheA binds to CheW, suggesting that these domains can interact with each other.	0.00074489
NZ_CP022098.1\|WP_095987044.1\|5451076_5452453_-\|diguanylate-cyclase	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	7.06331e-56
NZ_CP022098.1\|WP_095987054.1\|5465821_5466631_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.22333e-125
NZ_CP022098.1\|WP_095987052.1\|5463363_5464425_-\|ADP-ribosylglycohydrolase-family-protein	gnl\|CDD\|377122	pfam03747, ADP_ribosyl_GH, ADP-ribosylglycohydrolase. This family includes enzymes that ADP-ribosylations, for example ADP-ribosylarginine hydrolase EC:3.2.2.19 cleaves ADP-ribose-L-arginine. The family also includes dinitrogenase reductase activating glycohydrolase. Most surprisingly the family also includes jellyfish crystallins, these proteins appear to have lost the presumed active site residues.	4.85455e-42
NZ_CP022098.1\|WP_095987051.1\|5462360_5462786_+\|cyclase	gnl\|CDD\|176861	cd07819, SRPBCC_2, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	2.25223e-19
NZ_CP022098.1\|WP_043433682.1\|5447143_5447500_+\|response-regulator	gnl\|CDD\|381085	cd00156, REC, phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response regulators (PRRs). Two-component systems (TCSs) involving a sensor and a response regulator are used by bacteria to adapt to changing environments. Processes regulated by two-component systems in bacteria include sporulation, pathogenicity, virulence, chemotaxis, and membrane transport. Response regulators (RRs) share the common phosphoacceptor REC domain and different effector/output domains such as DNA, RNA, ligand-binding, protein-binding, or enzymatic domains. Response regulators regulate transcription, post-transcription or post-translation, or have functions such as methylesterases, adenylate or diguanylate cyclase, c-di-GMP-specific phosphodiesterases, histidine kinases, serine/threonine protein kinases, and protein phosphatases, depending on their output domains. The function of some output domains are still unknown. TCSs are found in all three domains of life - bacteria, archaea, and eukaryotes, however, the presence and abundance of particular RRs vary between the lineages. Archaea encode very few RRs with DNA-binding output domains; most are stand-alone REC domains. Among eukaryotes, TCSs are found primarily in protozoa, fungi, algae, and green plants. REC domains function as phosphorylation-mediated switches within RRs, but some also transfer phosphoryl groups in multistep phosphorelays.	4.92934e-27
NZ_CP022098.1\|WP_095987050.1\|5461342_5462308_+\|class-II-fructose-bisphosphatase	gnl\|CDD\|236536	PRK09479, glpX, fructose 1,6-bisphosphatase II; Reviewed.	0
NZ_CP022098.1\|WP_095987053.1\|5464510_5465806_+\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP022098.1\|WP_095987042.1\|5447667_5449308_+\|chaperonin-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0

>NZ_CP022098.1|WP_095987045.1|5452501_5453314_+|defective-in-fruiting-DifE
MPLFESGRRLCLLLEAGGTRFSVEATSVTEVAAPDPDQTNLRGVLEVQDLSVLLGGEPEPTPGMVVVLDVSPTLAVRVSSVVEVADVTRAIHFVLPSGLGDSLAALSHSAVMHKGRLYLELGADVLPHEPGVVTPPPLPTLHLFGFPPERSLVFESQGRLFGLPLPFISQVVMRGESFSALPGRGGAIAGLMPHGQVLWPLYSVPALLGGRAAAEDFLVLAEVEGRTLGLCASRVIGVYPRFDPTGNPGEFTVSGVPDPILFVDLWRMFS
>NZ_CP022098.1|WP_095987044.1|5451076_5452453_-|diguanylate-cyclase
MARLLLVDDDKMARELYGDSLRAVGHEVSTVATIAEAKEALEHGRYDVVVTDLLLPEGNGMEVLRYTKEHHPGIEVVVITGLDKVDPAVRALKSGAAEYLVKPVAPEVLQHAVNRALATRELLQENAALRRYVSLLETGQRISTTLDRGRLVTTTCAAFVGLAAASAVMLVQRDAQGKARVLGTQNLTGPAHENALLARLAPYLPTLSEARLLEGLPGPSPCGLAVPAQDGEDLLGCALLLYPSRPPADIAEATSFLARSLALALRNQGRLAQVEDLAYLDDLTHLFNTRYLHLVLDREVKSAQQTHGAFSLLFLDLDYFKTVNDTHGHLMGSQLLVEMAHVLKGCVRDRDVAVRYGGDEYVVLLRGTDSSAALKVAERIRRAVEKHRFLVPEGHALSLSTCIGVASFPEHTQDKATLLDLADRAMYRGKKGSRNVVYLAGENLEATPPARHSQPTGG
>NZ_CP022098.1|WP_095987043.1|5449409_5450966_-|hybrid-histidine-protein-kinase/response-regulator-SinK
MDTPAPLALLLQALEAGDLRAARAAAAELQRTRQGSTQLAAEVLHELRQPLLGVKAYTQMLTEEIGPRGALRQMLAQVERMEQIISDFTRLASERPAPQQAVSLVTHVQAAARAFALNPDSARIHLEVEAREELTVNGNGRLLEQLALNLLNNARDAVTGRGLVKVVLTLEDRAPVMYVADWGRGIPDAVLPRLFEPYVTGSKRGTGLGLAVCRRIAQEHHAQLEIVPPSVLSLQPAPTTVFRVRFPPPEPTPAALPGPAPLAPSPTPATVRRRLLVVDDEEIIRSVFKDLMGRECEVLEAAHAEEALALLERGRVDLILTDKNLPGLSGLELARRARQLDPHSRVILMTGYPSLVTAQEALELGLLDYLLKPFDDIREVRARLREALTGTTPLPRGLRPGSRRVDVLEDSPASARRLTEALALLGLEARVLTTASAEPTAEPPAAVVVSWDFAAAHGRQALALARQLGQGAPFVVLAEYLSQETMLESLRAGASGCLPRELETPELSRELSRLLHVA
>NZ_CP022098.1|WP_095987042.1|5447667_5449308_+|chaperonin-GroEL
MAAKEIFFHQSAREAILRGVRILSDAVAVTLGPKGRNVVIEKSFGSPTVTKDGVTVAKEIDLENKFENMGAQMVKEVASKTSDKAGDGTTTATVLARAIYEEGLKLVAAGHSPMDLKRGIDKAVEVVVAELKKLSKSTADKKAIAQVGTISANGDETIGNIIADAMEKVGKEGVITVEEAKGLETTLDVVEGMQFDRGYLSPYFVTNRERMETVLDDAYILISEKKVSSMQDMIPILEQVARSGKPLLIIAEDVEGEALATLVVNKIRGVLNVAAVKAPGFGDRRKELLKDIATLTGGTVVTEELGHKYDALTLNDLGRAKRITIDKDNTTIVDGAGKREEIEGRIKLIRSQTETTTSDYDREKLQERLAKLAGGVAVIHVGAATETEMKEKKARVEDALHATRAAVEEGIVPGGGVAYLRTLPALEKLKLGGEQDFGVDIIKKALQEPLRKIASNAGLEGPVIINKVREGQGAYGYNARTDVFEDLEKAGVIDPTKVERTALQNAASVASLLLTTEAMVAERPKKKAKGAGAGGAPDYGGDDMDY
>NZ_CP022098.1|WP_043433682.1|5447143_5447500_+|response-regulator
MNILVVDDDVELCTLLSRFLEKHGYTVYSASDALQALDILERHDVGLIISDYRMPHMDGIQFTGMLKADPRHQGTSVILMTGNADGNVQDKGLRKGVAMTLEKPLDFNQLLNLVRFAE
>NZ_CP022098.1|WP_157758590.1|5445978_5447064_-|tetratricopeptide-repeat-protein
MSPSMGKRTSKRAPADWEARLEGVAAAFDRGAHQEALAGADALLAEDDSLAEALHWRAAALTELGRLDEALETYSRAVKVAPDDLELLLSATECLVGRVGDDREAVEDGLALCARGRKLAQRAGDIELLFEFLLWEGIGLNQVGECARALTSLEAALGHVPRSVEARLERAIALFELCRFGEAEAVLEDLLGDAADEPWAHHYLGLLAERRGDGKAALGHFARARALAPEEFPPPVELGEEAFDKAVEDAVKALPTHVKEYLDNVTLAVEEIPKDEDLMGESPPLSPCILGVFRGSPVGERHSILGTFDPYPASIVLYQKNLERFARTREELIEQIGITVMHEVGHLMGLDEEDLWQRGLD
>NZ_CP022098.1|WP_095987041.1|5445523_5445865_-|hypothetical-protein
MYPSETPRDTALTVAAQGTDIGAESLRDRAFTRDEQAAHAPAYVAGLLALSGERLRLVAMAVEEELDPELLHALHNEADAEADSEGGIVLEARMPVPDEEEPDPDDGKGPLVT
>NZ_CP022098.1|WP_095987040.1|5444869_5445202_-|hypothetical-protein
MMTQKWMNGALIAVAVVLGAWSTDGIAAPEAHDKATTSATQVEWWSSSGERTGQQSSSSVDQSEKPNSTVGGQFGCPFNEYQCNDHCRSIGYKHGECGGFLWQECHCHRK
>NZ_CP022098.1|WP_157758589.1|5444420_5444807_+|hypothetical-protein
MLSEQHVRQLVSYFECIVNDVVNPEHSQLTDSSLDGTRRMVREGVTEDDVRQALAQKPARIVDGLQPGEGRWTAVQGQGDHPAHGPVELRAVLQVHEVHRHHDESEVRCGPEAGVPSCRVILDREGTQ
>NZ_CP022098.1|WP_157758588.1|5443541_5443955_-|hypothetical-protein
MTSTLLVLLSQPQQPALFSAGAVPSLAASTVGGWRNLMQRQLHLSLGARVFGKGRVNVDGRLAAQLAHRTMEVALNGPALGLGQPEARHLYSGQVRWRFSRTLYALAEGGPLLCPQADGALRPAAHALLGLGVDRAR
>NZ_CP022098.1|WP_095987047.1|5454807_5458302_+|valine--tRNA-ligase
MSDTTELPKSYDAKEVEARWYACWQERGYFRADADADKPAFSIVLPPPNVTGSLHLGHALTATIQDILVRWKRMSGFKTLWVPGTDHAGIATQMVVERELKQTEKKSRHDLGREKFLERVWEWKDKYGQRINEQQKVLGASLDWSRERFTMDPGVSAAVREVFVRLYEEGLIYRAQKLINWCPSCLTALSDLEVEHEEKQGSLWHIHYPVKGSDRRLTVATTRPETMLGDTAVAIHPEDPRYHGLAGQTVVLPLVGREIPIIVDAELVDPAFGTGVVKVTPAHDFNDYQTGLRHKLPQINILDEAARITSEGGPYAGMDRYAARKKIAEDLAAQGLLEKEEPHKLSVGGCQRCGTVVEPRLSPQWFVKIEPLAKPAIEAVEQGRTKIIPESWTNTYFHWMRNIHDWTISRQLWWGHQIPAWYCEECSPRLEATGTIDYSRAEPIVARTAPDKCSKCSGSRLTQDPDVLDTWFSSGLWPFSTLGWPEQTADLRAFYPNSVMETGHDILFFWVARMMMFGLHFMKDVPFRTIYLHAMVRDEKGEKMSKTKGNVIDPLDIVLGAPPEQLNKNLRNKYPQGMPAHGADALRFTLASLTQQGRDIKLSLDRVAGYKAFGNKLWNASRFALMNMGDFTLDSRPLTERPLTLADRWILSRLQRAIAVTRTSLEAYAFAEAASTLYQFLWSEFCDWYIELAKGSLYGEDAQAKDTTRAVLVFCLERILRLLHPFMPFITEEIWQKLPLTRQTDSIMIAPFPEPDVSLEDTAAEAEIGTVITAIEGLRNIRGESNLAPSARITAHVQSADARTRELLERWRGDVTRLAGLGELHIAAPGAKPPLSAAFVSAQLEIFVPLAGLIDVDAERERLGKEITRSEQELGGIKRKLDNPNFVAKAPPDVVEKDRARVEELEARVTKLRDNLERLSPQAAEPTSGQTVGDLEGRDSAPASTPASQPVTAKSVGDDDVVEAQLVQAEVISTEAVVEEDDEDDVVEAVVDTEEDDEDDVVEAVVDTEEEDDEDDVVEAIADEDEAEPEPAAPPARKSGSSRSVKAPAKKAASAKKAPAKKAPAKKAAPAKKAPAKKAASAKKAPAKKAPAKKAASAKKVPAKKAPAKKAASAKKAPAKKAPAKKAVSAKKAPAKKAPAKKAPAKSKGPARKQAKGKPAKSRR
>NZ_CP022098.1|WP_095992159.1|5458362_5459169_+|carboxylating-nicotinate-nucleotide-diphosphorylase
MEEDLGAAGDITTHALVPAEALGSAELIAKERLVIAGLDAFARVFQRVDPEVRIELLSSDGQEVQDRALVARVHGRLRSLLTAERTALNIVQRTSGMATMAHQVMDTVKGSRLRVLDTRKTSPGMRSLSKLAVKAGGAFNHRFGLFDGILIKDNHIAAVGGSVREALRRARANAPQLVKIEIEVTNLEQLAEALEEGADVVMLDNMDDAQISRAVELTAGRIPLEVSGGITLERLPRLAKLGVDFVSMGALTHSARAMDLSLEILQAS
>NZ_CP022098.1|WP_095987048.1|5459175_5460801_-|alkaline-phosphatase-family-protein
MFRPRAPLPLLLLLLALPAWAKPPRLTLFITVDAMGSDLLLRTRPRLQGGLGKLIDSGAFYPYARYDYAKPRTAPGHATLATGANPWRHGIVDNRVIDRATGKPARVFPDAQHPVLEAPLSEDDVSPANLLAETLADRLRLATNEQGKAVALSGKARSAIPLAGRLGQAYWFDETVGKFVTGTWYTKELPGWLKAFNAANPPTTWFGKTWEPVRKRTEYLGEDDRPYEGEYYGLGRVFPHPLTGGLTQPGPQAYSAFAISPLSLDLVVRAAGAAIAGEGLGKDEVPDLLAVSFSATDRVYHQYGPNSWEMQDTMFRLDKAVGDLVALAERAAGGRANLLVVLSADHGGAAAPEYWTAQGMEARRVSPGELSKGLTETLRQRFGGDVTATVEELDVYLGGKTLEGGKVDGAAVRRAAADWLSRQPAISLAVASDDLPTLPDVAGLATALRRGYYPGRSGDVLFVVKPFHVMSADTVGTNHGAPYAYDQLVPFVLAGKGVRPGSYMQQISTTDVAPTVAAALEMNLPASAEGHPRSEALGTGR
>NZ_CP022098.1|WP_095987049.1|5460897_5461299_+|acyl-CoA-thioesterase
MVEARIRVIYGDTDQMGVVYHANYFRYFEFARGEYFRARGGSYRDVEREGLMLPVVEASIAYKSPARYDDVLLVHARVSELKRASLTFHYDVRREGAPETLLCTGQTVHACVGRDGRPTRLPPVLVQLLQTAD
>NZ_CP022098.1|WP_095987050.1|5461342_5462308_+|class-II-fructose-bisphosphatase
MDRNLAMEVVRVTEMAAIASARLMGRGGKNESDQAAVDAMRRAFDALQINGTVVIGEGERDEAPMLYIGEEVGRRHADDPSVDIALDPLEGTNLCAYGRPGAIAVVAMADKGKLLNAPDTYMEKIAVGPRARGAIDLRRSPTENLRSIAERMKVYVADLTVIILERERHVELIKEVRAAGARIRLIDDGDVAGAIATCFEDTGVDVLMGTGGAPEGVIAAAAVRSVGGDMQGRLVPRNAEEVARAARMGITDISKIYSAEDLASGDVMFAATGVTTGDFLRGVRFFGGGCETHSVVMRSKTGTVRFIQSRHKFDKKPGYNF
>NZ_CP022098.1|WP_095987051.1|5462360_5462786_+|cyclase
MAGASRTIVINAPPEKLFDVIAQYEKYPEFLSEVKKIRVLERKDNTLKVQYEVDVIKTIRYTILVTEERPKRMSWTFVEGEVMKDNKGSWVLEPDGEGRTKATYTVELALGPLVPKAIVNALTETSLPKMLESFKRRAEAT
>NZ_CP022098.1|WP_071902205.1|5463153_5463333_+|hypothetical-protein
MLDAFIIEEIKRRERNRDDRDRPVLEIPLPRPDERPRRRSDAEDDEKPPRGVVIIDLLG
>NZ_CP022098.1|WP_095987052.1|5463363_5464425_-|ADP-ribosylglycohydrolase-family-protein
MPPRRPTESPPDIYPRLRGRGALLGLAVGDALGSTLKGRRLIAPAFPHLSDGVHRNMRGGGPFSLKPGQVGESGQMACCLAGGIRESGTYDTEAQMRRYLKWRPHAVGMDDYTKEVLTEMAESTLPKANAAQRLWLKDGRKRALNGSLARTPPIGVFFSKDASMRAMASFADSMLTHFDPHCLLACATLNASIAHALHAGEKLTKEDLFKATLRELAVMSAQLGRTLSSFVKEVSAATADVREDLSVSNQSDPLLYWPELHMHRKLDHVRVAFRLAYWELWHAPSFEAALVDVVNRGGDSDVNGAVTGALLGAFYGEDAIPALWRQAVLEALNFRAGPLWTLYHPKDMVLLAG
>NZ_CP022098.1|WP_095987053.1|5464510_5465806_+|phosphopyruvate-hydratase
MTEIAQIVAREVLDSRGNPTVEAEVLLAGGAKGRAAVPSGASTGEHEALELRDGDKGRYLGKGVRKAVEHITEKIAPELVGMDAADQYAVDQQMIEMDGTPTKGKLGANAILAVSMATARAAADAHGLPLYRYIGGSQARTLPVPLMNILNGGAHADTRVDVQEFMVVPAGAPSFSEGLRWGAEIFHALKKILKGRKLNTAVGDEGGYAPDLPANEEALKLIMEAISAAGFKAGEQVFLAMDVAASEFFDKGSKKYKLKGEGKEFDASGLLDYYQQLVSRYPIVSIEDGMAEDDWDGWKKITDVLGGKIQLVGDDLFVTNVERLSRGIEAGTANSILVKVNQIGSLTETFDAVRMAHKAGFTSVMSHRSGETEDTTIADLAVALDCGQIKTGSASRSDRIAKYNQLLRIEQELGAGARYAGMKSIKGLKAK
>NZ_CP022098.1|WP_095987054.1|5465821_5466631_+|5'/3'-nucleotidase-SurE
MKKGGEVAGTQQPRILVCNDDGYFSEGLRALVDAVSPLGEVWVVAPDREQSAASHAISLWRPLRLTEIRERWFSVDGTPADSAYLAIHHLLKDDRPKIMVSGINHGANLADDVNYSGTVAAAREAALLGIPSIAFSLVSRAPFDFQHAARFARSLVAAALAQPQLPPRMLLSVNVPSGEPRGYAVTRLGRHSYGYDVVEKEDPRGRKYYWIGGSTYAHEDLPGSDCNAVHDERLISVTPLNFELTDTPMLKDLSGWSLEGFPGAGRGGD

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_16

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_16

5718443-5719254

Orphan

Consensus_repeat	Method
GCTCGCTGGCCCANGGCGCC	CRT

12 spacers

The CRISPR arrays of NZ_CP022098_16

>merge|NZ_CP022098|16|5718443-5719254|CRT
GCTCGCTGGCCCATGGCGCCGCGAGTGGACACGGGCCCCTGGCCCAGGCCATCGCGAGCGCGTTGAGTTCGCTGGCCCATGGCGCCACGAGCGGGCCGAATGGGTTGCACCATGGGGCCGCGAGCGCGGTGGGCTCGCTGGCCCATGGCGTCGCGAGTGGACACGGAGGCCTGGCCCAGGGCCTCGCGGGCGCGGTGAGCTCGCTGGCCCACGGCGCCACGGGCGGACCGAATGGGCTGATGCATGGGGCCGCGGGCGCGGTGGGCTCGCTGGCCCATGGCGCCGCGAGTGGACACGGGCCCATGACCCAGGCCATCGCGAGTGCGGTGAGTTCGCTGGCCCACGGCGCCACGGGCGGACCGAATGGGCTGATGCATGGGGCCGCGGGCGCGGTGGGCTCGCTGGCCCATGGCGCCGCGAGTGGACACGGGGGCCTGGCCCAGGGCCTCGCGGGCGCGGTGAGCTCGCTGGCCCATGGCGCCACGGGCGGGCCGAATGGGCTGATGTATGGGACCGCGAGCGCGGTGGGCTCGCTGGCCCATGGCGCCGCGAGTGGACACGGGCCCCTGACCCAGGCCATCGCGAGCGCGGTGAGCTCGCTGGCCCATGGCGCCACGGGCGGGCCGCATGGGCTGATGCACGGGGCCGCGAGCGCGGTGGGCTCGCTGGCCTACGGCGCCGCGAGTGGACACGGGGGCCTGGCCCAGGGCCTCGCGAGTGCGGTGAGCTCGCTGGCCCACGGCGCCACGGGTGGACCGACTGGGCTGATGCACGGGGCCGCGAGCGCGGTGGGCTCGATGGCTCATGGCGCC

>NZ_CP022098|16|2|5718443-5719254|CRT
GCTCGCTGGCCCATGGCGCC	GCGAGTGGACACGGGCCCCTGGCCCAGGCCATCGCGAGCGCGTTGA
GTTCGCTGGCCCATGGCGCC	ACGAGCGGGCCGAATGGGTTGCACCATGGGGCCGCGAGCGCGGTGG
GCTCGCTGGCCCATGGCGTC	GCGAGTGGACACGGAGGCCTGGCCCAGGGCCTCGCGGGCGCGGTGA
GCTCGCTGGCCCACGGCGCC	ACGGGCGGACCGAATGGGCTGATGCATGGGGCCGCGGGCGCGGTGG
GCTCGCTGGCCCATGGCGCC	GCGAGTGGACACGGGCCCATGACCCAGGCCATCGCGAGTGCGGTGA
GTTCGCTGGCCCACGGCGCC	ACGGGCGGACCGAATGGGCTGATGCATGGGGCCGCGGGCGCGGTGG
GCTCGCTGGCCCATGGCGCC	GCGAGTGGACACGGGGGCCTGGCCCAGGGCCTCGCGGGCGCGGTGA
GCTCGCTGGCCCATGGCGCC	ACGGGCGGGCCGAATGGGCTGATGTATGGGACCGCGAGCGCGGTGG
GCTCGCTGGCCCATGGCGCC	GCGAGTGGACACGGGCCCCTGACCCAGGCCATCGCGAGCGCGGTGA
GCTCGCTGGCCCATGGCGCC	ACGGGCGGGCCGCATGGGCTGATGCACGGGGCCGCGAGCGCGGTGG
GCTCGCTGGCCTACGGCGCC	GCGAGTGGACACGGGGGCCTGGCCCAGGGCCTCGCGAGTGCGGTGA
GCTCGCTGGCCCACGGCGCC	ACGGGTGGACCGACTGGGCTGATGCACGGGGCCGCGAGCGCGGTGG
GCTCGATGGCTCATGGCGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_157758607.1\|5726559_5727291_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095987220.1\|5709227_5710088_+\|DUF2381-family-protein	unknown	unknown	gnl\|CDD\|370554
NZ_CP022098.1\|WP_095987230.1\|5722361_5722724_-\|DUF3565-domain-containing-protein	unknown	unknown	gnl\|CDD\|378808
NZ_CP022098.1\|WP_095987229.1\|5720627_5721338_-\|glutathione-S-transferase-family-protein	unknown	unknown	gnl\|CDD\|198297
NZ_CP022098.1\|WP_095987231.1\|5722934_5725139_+\|DUF4082-domain-containing-protein	unknown	unknown	gnl\|CDD\|372556
NZ_CP022098.1\|WP_095987218.1\|5707288_5708446_+\|cystathionine-gamma-synthase	unknown	unknown	gnl\|CDD\|181076
NZ_CP022098.1\|WP_095987222.1\|5711970_5712243_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095987235.1\|5728282_5729047_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372911
NZ_CP022098.1\|WP_095987224.1\|5713450_5714917_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373989
NZ_CP022098.1\|WP_095987219.1\|5708525_5708858_-\|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl\|CDD\|225209
NZ_CP022098.1\|WP_157758606.1\|5714928_5715663_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373953
NZ_CP022098.1\|WP_095987223.1\|5712319_5713108_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095992178.1\|5727307_5728087_-\|3-oxoacyl-ACP-reductase-FabG	unknown	unknown	gnl\|CDD\|183775
NZ_CP022098.1\|WP_095987227.1\|5715960_5717817_+\|lyase	unknown	unknown	gnl\|CDD\|271210
NZ_CP022098.1\|WP_095987233.1\|5726259_5726544_+\|DUF427-domain-containing-protein	unknown	unknown	gnl\|CDD\|377265
NZ_CP022098.1\|WP_095992177.1\|5721459_5722368_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|184959
NZ_CP022098.1\|WP_095987221.1\|5710104_5711904_+\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP022098.1\|WP_095987232.1\|5725229_5726129_+\|DUF2807-domain-containing-protein	unknown	unknown	gnl\|CDD\|371327
NZ_CP022098.1\|WP_095992176.1\|5719627_5720593_+\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|272913
NZ_CP022098.1\|WP_095987217.1\|5706249_5707377_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|181320

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095987220.1\|5709227_5710088_+\|DUF2381-family-protein	gnl\|CDD\|370554	pfam09544, DUF2381, Protein of unknown function (DUF2381). This family consists of at least 8 paralogs in Myxococcus xanthus, a member of the Deltaproteobacteria. The function is unknown.	1.93742e-71
NZ_CP022098.1\|WP_095987230.1\|5722361_5722724_-\|DUF3565-domain-containing-protein	gnl\|CDD\|378808	pfam12088, DUF3565, Protein of unknown function (DUF3565). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 30 to 78 amino acids in length. This protein has two conserved sequence motifs: WVA and CGH.	2.40638e-31
NZ_CP022098.1\|WP_095987229.1\|5720627_5721338_-\|glutathione-S-transferase-family-protein	gnl\|CDD\|198297	cd03188, GST_C_Beta, C-terminal, alpha helical domain of Class Beta Glutathione S-transferases. Glutathione S-transferase (GST) C-terminal domain family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. The GST fold contains an N-terminal thioredoxin-fold domain and a C-terminal alpha helical domain, with an active site located in a cleft between the two domains. GSH binds to the N-terminal domain while the hydrophobic substrate occupies a pocket in the C-terminal domain. Unlike mammalian GSTs which detoxify a broad range of compounds, the bacterial class Beta GSTs exhibit GSH conjugating activity with a narrow range of substrates. In addition to GSH conjugation, they are involved in the protection against oxidative stress and are able to bind antibiotics and reduce the antimicrobial activity of beta-lactam drugs, contributing to antibiotic resistance. The structure of the Proteus mirabilis enzyme reveals that the cysteine in the active site forms a covalent bond with GSH. One member of this subfamily is a GST from Burkholderia xenovorans LB400 that is encoded by the bphK gene and is part of the biphenyl catabolic pathway.	1.30865e-19
NZ_CP022098.1\|WP_095987231.1\|5722934_5725139_+\|DUF4082-domain-containing-protein	gnl\|CDD\|372556	pfam13313, DUF4082, Domain of unknown function (DUF4082). This family appears to be a parallel beta-helix repeated region that sits between successive Cadherin domains, pfam00028.	7.78284e-59
NZ_CP022098.1\|WP_095987218.1\|5707288_5708446_+\|cystathionine-gamma-synthase	gnl\|CDD\|181076	PRK07671, PRK07671, bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase.	2.4864e-169
NZ_CP022098.1\|WP_095987232.1\|5725229_5726129_+\|DUF2807-domain-containing-protein	gnl\|CDD\|371327	pfam10988, DUF2807, Putative auto-transporter adhesin, head GIN domain. This bacterial family of proteins shows structural similarity to other pectin lyase families. Although structures from this family align with acetyl-transferases, there is no conservation of catalytic residues found. It is likely that the function is one of cell-adhesion. In Structure 3jx8, it is interesting to note that the sequence of contains several well defined sequence repeats, centred around GSG motifs defining the tight beta turn between the two sheets of the super-helix; there are 8 such repeats in the C-terminal half of the protein, which could be grouped into 4 repeats of two. It seems likely that this family belongs to the superfamily of trimeric auto-transporter adhesins (TAAs), which are important virulence factors in Gram-negative pathogens. In the case of Parabacteroides distasonis, which is a component of the normal distal human gut microbiota, TAA-like complexes probably modulate adherence to the host (information derived from TOPSAN).	3.01322e-24
NZ_CP022098.1\|WP_095987235.1\|5728282_5729047_-\|hypothetical-protein	gnl\|CDD\|372911	pfam14099, Polysacc_lyase, Polysaccharide lyase. This family includes heparin lyase I, EC:4.2.2.7. Heparin lyase I depolymerizes heparin by cleaving the glycosidic linkage next to an iduronic acid moiety. The structure of heparin lyase I consists of a beta-jelly roll domain with a long, deep substrate-binding groove and an unusual thumb domain containing many basic residues extending from the main body of the enzyme. This family also includes glucuronan lyase, EC:4.2.2.14. The structure glucuronan lyase is a beta-jelly roll.	3.1104e-83
NZ_CP022098.1\|WP_095987224.1\|5713450_5714917_+\|hypothetical-protein	gnl\|CDD\|373989	pfam15648, Tox-REase-5, Restriction endonuclease fold toxin 5. A predicted toxin of the restriction endonuclease fold present in bacterial polymorphic toxin systems. In bacterial polymorphic toxin systems, the toxin is exported by the type 2, type 5, type 6, or PrsW-peptidase dependent secretion system. Versions of this domain are also found in caudoviruses.	4.41875e-21
NZ_CP022098.1\|WP_095987219.1\|5708525_5708858_-\|antibiotic-biosynthesis-monooxygenase	gnl\|CDD\|225209	COG2329, COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only].	1.02279e-14
NZ_CP022098.1\|WP_157758606.1\|5714928_5715663_+\|hypothetical-protein	gnl\|CDD\|373953	pfam15579, Imm52, Immunity protein 52. A predicted immunity protein with an alpha+beta fold and conserved tryptophan and phenylalanine residues, and a GT motif. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, usually containing a domain of the Tox-REase-5 family.	1.66526e-32
NZ_CP022098.1\|WP_095992178.1\|5727307_5728087_-\|3-oxoacyl-ACP-reductase-FabG	gnl\|CDD\|183775	PRK12826, PRK12826, SDR family oxidoreductase.	8.39678e-108
NZ_CP022098.1\|WP_095987227.1\|5715960_5717817_+\|lyase	gnl\|CDD\|271210	cd14251, PL-6, Polysaccharide Lyase Family 6. Polysaccharide Lyase Family 6 is a family of beta-helical polysaccharide lyases. Members include alginate lyase (EC 4.2.2.3) and chondroitinase B (EC 4.2.2.19). Chondroitinase B is an enzyme that only cleaves the beta-(1,4)-linkage of dermatan sulfate (DS), leading to 4,5-unsaturated dermatan sulfate disaccharides as the product. DS is a highly sulfated, unbranched polysaccharide belonging to a family of glycosaminoglycans (GAGs) composed of alternating hexosamine (gluco- or galactosamine) and uronic acid (D-glucuronic or L-iduronic acid) moieties. DS contains alternating 1,4-beta-D-galactosamine (GalNac) and 1,3-alpha-L-iduronic acid units. The related chondroitin sulfate (CS) contains alternating GalNac and 1,3-beta-D-glucuronic acid units. Alginate lyases (known as either mannuronate (EC 4.2.2.3) or guluronate lyases (EC 4.2.2.11) catalyze the degradation of alginate, a copolymer of alpha-L-guluronate and its C5 epimer beta-D-mannuronate.	8.21154e-135
NZ_CP022098.1\|WP_095987233.1\|5726259_5726544_+\|DUF427-domain-containing-protein	gnl\|CDD\|377265	pfam04248, NTP_transf_9, Domain of unknown function (DUF427). This domain contains a beta-tent fold.	1.25652e-17
NZ_CP022098.1\|WP_095992177.1\|5721459_5722368_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|184959	PRK14997, PRK14997, LysR family transcriptional regulator; Provisional.	2.20621e-64
NZ_CP022098.1\|WP_095987221.1\|5710104_5711904_+\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.32803e-47
NZ_CP022098.1\|WP_095992176.1\|5719627_5720593_+\|peptidylprolyl-isomerase	gnl\|CDD\|272913	TIGR00115, tig, trigger factor. Trigger factor is a ribosome-associated molecular chaperone and is the first chaperone to interact with nascent polypeptide. Trigger factor can bind at the same time as the signal recognition particle (SRP), but is excluded by the SRP receptor (FtsY). The central domain of trigger factor has peptidyl-prolyl cis/trans isomerase activity. This protein is found in a single copy in virtually every bacterial genome. [Protein fate, Protein folding and stabilization].	9.83407e-28
NZ_CP022098.1\|WP_095987217.1\|5706249_5707377_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|181320	PRK08247, PRK08247, methionine biosynthesis PLP-dependent protein.	0

>NZ_CP022098.1|WP_095987227.1|5715960_5717817_+|lyase
MARRQLVIGSSLLLGLTPFPGFAADERFSIPPTSVTASTDDGNVPANTVDGDLTTRWSAEGDGQWLQLDLGSPKKVAFVKIAFLNGASRTSTFDIQTSPDGTTFSTVRSKATSSLTSGLQTFDFPDVGSARYVRLVGYGNSANAWNSYLEVEVHGSAAEAPSGNIVNVSTAAQLTTALASATAGTTIVLADGTYTNSGAFVLKGKNATSSSPITLKAANRGKAIISGGASLQVTSSSHVVISGLKFTNTGNSALVLDGSNNIRVTRNTFALIEDGTQIKWLLIKGAGSHHNRIDHNDFGGKSNIDPVIALDGNYSSQMTQYDVIEYNYFHDVGPRLANGLETIRLGLSALSLLDAHATVQYNLFENCDGDPEFISIKSGHNTIRYNTIITSQGQLTARHGNNNSIYGNFILGDGSKSGVGGIRLYGTDHKVYNNYLAKLTDDALLIDGGDFDGGPTSSTYTASDLSKHWRVYRAEVVNNTVVDSTAGLLIGKKYTYAPVDSKVANNLIRNTTGTLYNELKTSNTLFQGNIGYGSALSNKSRTSSEIRNVNPSLTAVNGLQKLSSTSQAINAATGAYTYVAEDMDGQLRAANDVGADEYSTDPIDHAPLSSADVGPNAP
>NZ_CP022098.1|WP_157758606.1|5714928_5715663_+|hypothetical-protein
MSESYAIKGYWGRRPESAEECARRAETFFRLLAECHPGYARWYRQNTAVANLAELQFEPSRATFEEFFGRKRYQSGKDGFHFGAWTGHENQDQGGMVMFGCGSKAEVAPNFLWLFFPQEALGSGNLLSATVVAGVMRALAVAWEPEWAVATEDGLWDQLSGGSRLGCFVGWMTYFSRERGEVPALPAPVLVEPVGDKGTLVTLTSERLTPSNPEHVEFAWRVQKLLEERGLFRLMVHPSAMRKA
>NZ_CP022098.1|WP_095987224.1|5713450_5714917_+|hypothetical-protein
MANEYRSPGAGEGGGTQLEDRRSPRGRPWWASHGVVLVLLGLQTACAMGYPMGGMIAGPTRHWGRVQRQRTVHEERAGDARAVVSVTQDAPSENLEADAAEAAEAAGPVEVSAAEEGARPRRARELDDEENLEGKGLGWPDGVGDGRPFTVPMSLNYFQGFLVQAGVPSAALPKDGRTLSPQQALALLPHLLSTPVTLGNFGMRRMAAHMLMEVDTVEGLYRLVFHTGETLEGLAQLPGAVRQLYENSPRLWEEFRHKPYAEKVRTISRLATGAVLTVGTAGAGAAKAAAWGGKLGSLTVPLLSLSGDGLLAVRLAAVPVGSVATAAASALSSTYVLHMANTSVQGAGGGGGWPPVGGPGQWVEDTTSMSEQARDYQAQVTGAPRRWAYRVCRDGECVNYDGYDPKTGTLLEAKAREYQKWFNEELNPRFKYEGLEGMIDQAGRQLRLAGGLPVRWHVAEPRMVAVLRKHFDARGLHAIEVVYTKPEP
>NZ_CP022098.1|WP_095987223.1|5712319_5713108_+|hypothetical-protein
MTNPLILSDAQQTIGRRWNDGQSLDQARILGLARDALDFISATGQWYPFDDSRVGGWHHGSPPAADERSTQLHEQLCKTEAFFERLLNDPTAADEQPAIQVILDALRFISSTRQHEAFAHFLEHLEANAPPYVMAAFDSREEAEAWLQKHPSPPLFAEVLIGNKPHDVVYVRETNFRRLPWNRRLHQYLSWLEEFDPPDAEASFSTLEEAEAWLMRQAHPAKRTWVKVAGEFYLAVYYSNINHRALFPMSMAVRGSKELKSS
>NZ_CP022098.1|WP_095987222.1|5711970_5712243_-|hypothetical-protein
MKTEESALWFCAKIKAIRTEAGHDVEKLEALAQSPELVAEAAARFPDDPFLAAQVRTAIELELPLARREIFLLDGPPTDEQIAELHRQNK
>NZ_CP022098.1|WP_095987221.1|5710104_5711904_+|serine/threonine-protein-kinase
MTMESLHPDHLQPGHVVGPWLIVQVLGRGGSSRVFKVERDGRPYSMKMALRPITQFKEGFSEEKYVEEKSAYRQLAREAAALFTYSSHPNLLRVYGVDFWPNPAQGYPFLITDYVEGDTWHEWRWRTPPHAMGLVDTFSDVVRTVGVLHARGVYHRDLKAENILIRRADGRPFLIDFGTARLPGALTKTLGLPEGALHLVPPELLAYTRTEAWKRGEAFQGGVAADLYALGVLLYQGLTDLHPFNPELPDEELVAAIATRPPKAPHLLNPLAPRSLSDIAMKLLEKRPEDRYPDTQALLEALEKAAEKERQSPAWRRPLFAVEGSPAAEPMLQEVAEQPAQPPETASAEPEEAQPPEKEASQAAPQEPPAAPARPRRTTWPRVLLAGLIVLGLALWLVRSTLAPPPEALLPGSGPEKGSPPVPTPSRSAPSSFLAAWLCAVVGAGCPAAQVKPPEPADCPREATEAMFKELKILTGSFLTAVVDVNQPSGLGVPGVYQDGPVVSQIVEGDGNMPAGTLLHGRLWTGPGIYDTYSEMDVQKKRPAVMGRYTLAVLPDGRQYPVCIILGDHVGRVPKLEGSKEGAAVLSRELPVSAVWSWP
>NZ_CP022098.1|WP_095987220.1|5709227_5710088_+|DUF2381-family-protein
MSLTLLLTGATAAAQPHPPARERQERRVTLSGNPEEAGPEVSVAAGTATYIRFDAPIDKASVEVEGRSMRFRWVDVGERLVAVEPSVDLGVEEKLVVRVRYKDGASPVGVTLVLASHPTRVDKEVEVVRRPRTVESLEAALAEKEAELATLRASSGLAGLVFSGRLGPDGVQARRIMRAPEGAWGGLKVAGGEGYRASSWALAVVRVRNLPGQSPWRPGVARLIRADGTALKVLSVDMNKAQLAPGEEGIVTVEPEAPSWKMGDVFRLELLDESGVRPLPTLDVAL
>NZ_CP022098.1|WP_095987219.1|5708525_5708858_-|antibiotic-biosynthesis-monooxygenase
MSIANTPEPPYVAVIFTSVRTPVDEGYAVTSEEMVSMAAAQPGFLGMESARGTDGLGITVSYWRDMESVRAWKAVAEHRTAQRLGRERWYRAYRTRISLVEREYGFSPGR
>NZ_CP022098.1|WP_095987218.1|5707288_5708446_+|cystathionine-gamma-synthase
MTSSPTWPKRSKELAVRTRFATRLLHTGHETDPATGAAAVPIYQVSMFDQPGLDQPGEFDYARSGNPTRKALEGVLAELDEAHAAFAFGSGMAAISTVLMLFSAGDHLVVTDDCYGGTYRVLTRVFSRFGLKATFVDTSDPDAVRAAIRPNTKALLVESVSNPFLKRTDILAMSILARTCGALLIVDNTFLSPYVSRPITEGADIVVHSATKYLGGHSDIVAGTVAVKTAELAREVYFLQNAVGAVLGPQDCFLLQRGIKTLGVRMERQVRTAAGLARWLADRTEVKEVFYPGAGAVVSFRLARDEWAAPFVEALQLPLLGVSLGAVESIVTVPARHSHASVPAPERQRRGITDGLIRYSVGLEELEDLQEDLALALGQAVRVAA
>NZ_CP022098.1|WP_095987217.1|5706249_5707377_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MKLATALVHSGVRRDPTTGAVAVPIYQSATYQHPALGQSTGYDYSRTKNPTRSALEDALARLEGGSQGLAFSSGMAALHCALQLFGPEDHVLLTEDLYGGTYRLVDRILHVPFTFVDTTRPEAVRAALRPNTRAILVESPTNPLMKTADIPAIAHIAHEAGALLIVDNTFFTPWLQRPLELGADIVVHSATKYLAGHNDVVAGALVVRDATLGERLAYIQNGIGAILGPQDAYLVIRGLKTLALRMEKHQANAREVAAWLATHPLVERVFYPGVGGMLSFNVTEAALVPGVLASVQVCLFAESLGGVETLITYPTTQTHADIPVARREQLGISDRLLRLSVGIEDCHDIIADLAQALEGARCANPLRDAPAAHRA
>NZ_CP022098.1|WP_095992176.1|5719627_5720593_+|peptidylprolyl-isomerase
MIAPSLEGLSVIVPAPEPITARRVQERFQELARAHASERMRPRTEGLAWGDEVLVDIAGYSNGRLIPFSVRTDVWLPLAPDPLLPGLYEQWVGHLPGESVLVDIVLGENYPLEALRGQPARFALLIQAAREVKYPDPTNPEFLEALGRGATLDEVMRGVAKELQQEAARARFLEGQQRVLEEVAARTQVDIPEELVNEEIRLRWGASEGRSVTKLKFSNKHQEESLQTWLADERTRAEARQRLRISLALGAICKRDGLILTPAKVLEVIQAESTAAGVPLEQATAVFASEPQQHARITQAAWHLLAVDHVMSKAQVHGAGT
>NZ_CP022098.1|WP_095987229.1|5720627_5721338_-|glutathione-S-transferase-family-protein
MSPILFYGVPSGCSFGSIVALEWLARPYRLCRIEMPSVVTSDTYKRINPLAETPSLMTADGRVISETIALLNHLGPLGIDRRLAFPQGTHDFDRWNQMLAFLNTTFFGSFSPLWYAYEHALEPEAKRALTDYGRAKVEKAHARLEALLGDRPWLLGEHRTWVDAYFIGIARWTRYHDAVDRRAFPNVRRLIEKLEADPAVKFAHAIEQQRPAVSAGGFEGEVRLEDAVESIRRAAA
>NZ_CP022098.1|WP_095992177.1|5721459_5722368_+|LysR-family-transcriptional-regulator
MLNLNDLALFVAAIEHGGFAAAARRLGVPKATISKRVAELEASLDARLVHRTSRSFTLTEVGRDFHERARAVLIEAEAAEQVVRGRIAEPSGTVRLTASVPTAQLYLAEHLPKLARAYPKLRVQLDVTDRFVDVVQEGYDIAVRSHFTPLPASGLVQRQLVSEPIILVAAPDYLATREPLERPEQLGRHDGLVAALNPMGWRLLGPAGERVEVSPITVMAANESTVLLGAAKAGLGVACLPESMCRGALRSGELVRVLPEWVAGTVTTTLLMPHRRGQLPGVRATVEFLIECLAQKVRASTH
>NZ_CP022098.1|WP_095987230.1|5722361_5722724_-|DUF3565-domain-containing-protein
MKQKMTGFHLDGENHWVAELECGHRQHVRHEPPWMERPWVLTEEGRRSRLGIELDCRRCDEVGHAVAEAVREALAAAARQAYEEAGLSGLCAEGRWELALDAIRATGLTSAIHRALTRPQ
>NZ_CP022098.1|WP_095987231.1|5722934_5725139_+|DUF4082-domain-containing-protein
MLRHASRWVTTLVVGFTWVQAGCAPAEPTAPETPRTEEAAQPLLPGERSLFDASAVPAVAAADDSAAVELGVRFRSDAPGRIMGVRFYKGAGNTGTHTGSLWSASGALLATATFQGETASGWQEVRFATPVAIAADTNYVASYHAPAGHYAATSNGFASALDVPPLHAPASGTEGGNGLYHYGTSGFPTDSYQASNYWVDVAFQPNDTTPPRAPTNVVATPNSSTAIDLTWYVSVDGSGETQGNARAHLVYRGSQLIAELSGTTTSYRDTGLMPATTYEYTVRGRDAAGNLSPASATVTATTLASSVCNPCSLWNVVTGDPQFVNADATPTEVGLKFRTDVAGTVTKVRYYKSSVDTGPHVGHLWSATGELLGTTVQAPGESSFGWRELTFPTPVSLAANTTYVVSYFATVGYYAITPNYFSSAGVDVPPLHAPSAVAAGGNGVRHLNGSGFPSDAWMNTNFWVDVAFVPATGDASPVDVSVEHAFPAGTGVRGDALDYDITVTNHGTRAATNLTLDVPVPTGLAPFVFTPKASVGTCGYYTTDNMHCDITSLSAGESAVVRMTLVPSISGTFQFQATVAASETDSVPGNNTSTLTIPVGPSSNLVTFDTFDGADEAITGIHGPFYFVFNKWYLASPWGGFTTKSISFNGGGVNQGELSIYGERTVVGLDAFTWDTGATLTLSCFNQPTRTFTLTPGQVTHVVTNWQGTCSSVTLATSNGWDTNFDNIELSPLP
>NZ_CP022098.1|WP_095987232.1|5725229_5726129_+|DUF2807-domain-containing-protein
MRCSSDRTRESARSAGVIFRRGNMRKSLGWSVAALMFMPACGWFGEQGNGHKVTQPRELTGFTRVENHSSLDVVVREASAGSVTLTLDENLLPFVTTRVSGETLFIENTENLSYSGEGRVVATLPRFLGAENDGSGDFLVEGVTQSNALSFELEGSGDMDYCGPASSLTVNLSGSGNMTLCTPREQVLDGVRLGLSGSGSLTYDGATKSLEAVLEGSGDMSLTGSAPRLVARVNNSGNLEARGLTSSEAELYMAGSGNVSATVATTVTVHIDGSGNVDLWGDASLRDVRLEGSGSLRRH
>NZ_CP022098.1|WP_095987233.1|5726259_5726544_+|DUF427-domain-containing-protein
MRATLRGRVIAESADTVEVGGYHYFPRASVQMELLRLAPKTDSDRACPHGVQFYDVSDGNGRSERAAWSYEAPQASMKRVDHWIGFWGDVELAP
>NZ_CP022098.1|WP_157758607.1|5726559_5727291_-|hypothetical-protein
MNRYLPTGLLAGFLLCTSSAANAESPARAFVRLDEATTGRVERAVELRIQRSADGEQGYAVKNSGKWRDGPCRSGGPSGLSVLLVDFDFDGHADLWVTGVTDGQGRVRCSDVWLYKPQLKHYERHSELSSIQNLEIDPDAKQLEGGMWNCGCAGMCFFHETHGWSSGSLSKLSRREQDCGSEDIVYREFSVDSGAMKLTREVKGEPGFEEYDRRQKGILKFLDWGSVKQVRQWEAVRKSGRGP
>NZ_CP022098.1|WP_095992178.1|5727307_5728087_-|3-oxoacyl-ACP-reductase-FabG
MAESLKGKSVIVTGASKGIGKGIARVFARHGAKVLVVGRDLQAAEAVAREFVSAGGTASGFSADVTRLEDMEKMARVAAELHGGIDVLCANAGVFPQVKMEDMSPETWDEVMATNLKGTFLSVKACIPYLKKSSQGRIVITSSITGPTTGFPGWTHYGASKAGQLGFMRTACMELAKYGITVNAVLPGNIVTEGLEKLGPDYMKGMAAAVPLGKLGEVEDIGHAALFFASREAGYITGQTLIVDGGQVLPESPDALAQM
>NZ_CP022098.1|WP_095987235.1|5728282_5729047_-|hypothetical-protein
MKIKNIGMTVGIALLSHSLVAQAGEAFNNTGTVSGWNSINKEHKGSVTEVTNVTHSGPTAIKVTQIYDSAYSGRYHSEVVKNNVYRRGDTGFYGFAFRLQQDWQFQPQSYNIAQFIADFSNTGCDDYMPSSMIWLSGNQLFTRVKQGSVCSQKTVTFGNLATVTAGVWHKIVIQAKWASDGTGFYKLWFDGQKVLEQYNLSTTVSDDRYFQFRVGLYANGWHDSGYMQGSQGTRSIWFDEIGAGTTFADADPDQ

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_17

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_17

6605168-6605371

Orphan

Consensus_repeat	Method
AGCTGGAGCTGGAGGCCAGCGGCGGCG	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP022098_17

>merge|NZ_CP022098|17|6605168-6605371|CRISPRCasFinder
AGCTGGAGCTGGAGGCCAGCGGCGGCGGTGAGCTGCTCGTCGCCGGGGTGGACACGAAGAAGCTGGAGGTGGAGGCCAGCGGCGGCGCGGAGGTGACCCTCCGGGGCCGCGCGGCGGAGATGAAGGTGGAGGGCAGTGGCGGCTCGACCATCCAGGCGCGCAAGGTCCAGGTGGAGACGCTGGTGGTGGAGGCCAGCGGGGGCA

>NZ_CP022098|17|15|6605168-6605371|CRISPRCasFinder
AGCTGGAGCTGGAGGCCAGCGGCGGCG	GTGAGCTGCTCGTCGCCGGGGTGGACACGAAGA
AGCTGGAGGTGGAGGCCAGCGGCGGCG	CGGAGGTGACCCTCCGGGGCCGCGCGGCGG
AGATGAAGGTGGAGGGCAGTGGCGGCT	CGACCATCCAGGCGCGCAAGGTCCAGGTGGAGA
CGCTGGTGGTGGAGGCCAGCGGGGGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_095987838.1\|6603074_6603968_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095992250.1\|6615635_6617012_+\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|238624
NZ_CP022098.1\|WP_095987847.1\|6613543_6614647_-\|peptidase-M35	unknown	unknown	gnl\|CDD\|199915
NZ_CP022098.1\|WP_095987843.1\|6608572_6609358_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223673
NZ_CP022098.1\|WP_095987835.1\|6596940_6597660_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373953
NZ_CP022098.1\|WP_095987842.1\|6606557_6607592_+\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|238527
NZ_CP022098.1\|WP_157758674.1\|6597656_6599009_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373989
NZ_CP022098.1\|WP_095992249.1\|6614929_6615562_-\|glutathione-S-transferase-family-protein	unknown	unknown	gnl\|CDD\|223698
NZ_CP022098.1\|WP_095987841.1\|6605625_6606561_+\|ATP-grasp-domain-containing-protein	unknown	unknown	gnl\|CDD\|223267
NZ_CP022098.1\|WP_095992248.1\|6610919_6611804_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095987832.1\|6593374_6594379_-\|polyprenyl-synthetase-family-protein	unknown	unknown	gnl\|CDD\|223220
NZ_CP022098.1\|WP_095987846.1\|6612797_6613433_-\|protease	unknown	unknown	unknown
NZ_CP022098.1\|WP_095987844.1\|6609388_6610426_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|378117
NZ_CP022098.1\|WP_095992247.1\|6601496_6601943_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095987845.1\|6611822_6612689_-\|acyl-CoA-thioesterase-II	unknown	unknown	gnl\|CDD\|224857
NZ_CP022098.1\|WP_095987834.1\|6596087_6596855_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095987839.1\|6603964_6604687_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095987833.1\|6594557_6596078_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340883
NZ_CP022098.1\|WP_095987837.1\|6602204_6603017_+\|siderophore-interacting-protein	unknown	unknown	gnl\|CDD\|99790
NZ_CP022098.1\|WP_095987831.1\|6592805_6593378_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224427

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095987847.1\|6613543_6614647_-\|peptidase-M35	gnl\|CDD\|199915	cd11306, M35_peptidyl-Lys, Peptidase M35 domain of peptidyl-Lys metalloendopeptidases. This family M35 Zn2+-metallopeptidase extracellular domain is mostly found in proteins characterized as peptidyl-Lys metalloendopeptidases (MEP; peptidyllysine metalloproteinase; EC 3.4.24.20), including some well-characterized domains in Aeromonas salmonicida subsp. Achromogenes (AsaP1) and Grifola frondosa (GfMEP). These proteins specifically cleave peptidyl-lysine bonds (-X-Lys- where X may even be Pro) in proteins and peptides. AsaP1 peptidase has been shown to be important in the virulence of A. salmonicida subsp. achromogenes, having a major role in the fish innate immune response. Members of this family contain a unique zinc-binding motif (the aspzincin motif), defined by the HExxH + D motif where an aspartic acid is the third zinc ligand and is found in a GTXDXXYG or similar motif C-terminal to the His zinc ligands.	1.044e-80
NZ_CP022098.1\|WP_095987845.1\|6611822_6612689_-\|acyl-CoA-thioesterase-II	gnl\|CDD\|224857	COG1946, TesB, Acyl-CoA thioesterase [Lipid metabolism].	5.3034e-143
NZ_CP022098.1\|WP_095987837.1\|6602204_6603017_+\|siderophore-interacting-protein	gnl\|CDD\|99790	cd06193, siderophore_interacting, Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from transferrin and lactoferrin for bacterial uptake, contributing to pathogen virulence. Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport mechanism of photosystem I. FNR transfers electrons from reduced ferredoxin to FAD (forming FADH2 via a semiquinone intermediate) and then transfers a hydride ion to convert NADP+ to NADPH. FNR has since been shown to utilize a variety of electron acceptors and donors and has a variety of physiological functions including nitrogen assimilation, dinitrogen fixation, steroid hydroxylation, fatty acid metabolism, oxygenase activity, and methane assimilation in a variety of organisms. FNR has an NAD(P)-binding sub-domain of the alpha/beta class and a discrete (usually N-terminal) flavin sub-domain which vary in orientation with respect to the NAD(P) binding domain. The N-terminal moeity may contain a flavin prosthetic group (as in flavoenzymes) or use flavin as a substrate. Because flavins such as FAD can exist in oxidized, semiquinone (one-electron reduced), or fully reduced hydroquinone forms, FNR can interact with one and two electron carriers. FNR has a strong preference for NADP(H) vs NAD(H).	4.32558e-102
NZ_CP022098.1\|WP_157758674.1\|6597656_6599009_-\|hypothetical-protein	gnl\|CDD\|373989	pfam15648, Tox-REase-5, Restriction endonuclease fold toxin 5. A predicted toxin of the restriction endonuclease fold present in bacterial polymorphic toxin systems. In bacterial polymorphic toxin systems, the toxin is exported by the type 2, type 5, type 6, or PrsW-peptidase dependent secretion system. Versions of this domain are also found in caudoviruses.	2.38981e-18
NZ_CP022098.1\|WP_095992249.1\|6614929_6615562_-\|glutathione-S-transferase-family-protein	gnl\|CDD\|223698	COG0625, Gst, Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	7.68862e-19
NZ_CP022098.1\|WP_095987842.1\|6606557_6607592_+\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|238527	cd01094, Alkanesulfonate_monoxygenase, Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin mononucleotide (FMNH2), which is provided by the NADPH-dependent FMN oxidoreductase (SsuE).	5.96943e-80
NZ_CP022098.1\|WP_095987843.1\|6608572_6609358_+\|ABC-transporter-permease	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	8.66676e-59
NZ_CP022098.1\|WP_095987833.1\|6594557_6596078_+\|MFS-transporter	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.15759e-22
NZ_CP022098.1\|WP_095987844.1\|6609388_6610426_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|378117	pfam09084, NMT1, NMT1/THI5 like. This family contains the NMT1 and THI5 proteins. These proteins are proposed to be required for the biosynthesis of the pyrimidine moiety of thiamine. They are regulated by thiamine. The protein adopts a fold related to the periplasmic binding protein (PBP) family. Both pyridoxal-5'-phosphate (PLP) and an iron atom are bound to the protein suggesting numerous residues of the active site necessary for HMP-P biosynthesis. The yeast protein is a dimer and, although exceptionally using PLP as a substrate, has notable similarities with enzymes dependent on this molecule as a cofactor.	2.08763e-34
NZ_CP022098.1\|WP_095987832.1\|6593374_6594379_-\|polyprenyl-synthetase-family-protein	gnl\|CDD\|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	4.55765e-55
NZ_CP022098.1\|WP_095992250.1\|6615635_6617012_+\|amidohydrolase-family-protein	gnl\|CDD\|238624	cd01299, Met_dep_hydrolase_A, Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a conserved metal binding site, involving four histidines and one aspartic acid residue. In the common reaction mechanism, the metal ion (or ions) deprotonate a water molecule for a nucleophilic attack on the substrate. The function of this subgroup is unknown.	1.31986e-79
NZ_CP022098.1\|WP_095987841.1\|6605625_6606561_+\|ATP-grasp-domain-containing-protein	gnl\|CDD\|223267	COG0189, RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) [Coenzyme metabolism / Translation, ribosomal structure and biogenesis].	9.68064e-10
NZ_CP022098.1\|WP_095987835.1\|6596940_6597660_-\|hypothetical-protein	gnl\|CDD\|373953	pfam15579, Imm52, Immunity protein 52. A predicted immunity protein with an alpha+beta fold and conserved tryptophan and phenylalanine residues, and a GT motif. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, usually containing a domain of the Tox-REase-5 family.	4.59495e-28
NZ_CP022098.1\|WP_095987831.1\|6592805_6593378_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|224427	COG1510, COG1510, Predicted transcriptional regulators [Transcription].	6.44733e-15

>NZ_CP022098.1|WP_095987839.1|6603964_6604687_+|hypothetical-protein
MKTSAPLLLALLALCACGYREEGTRLHLGLDFRPAGDVHTQGSTREFLDDRGDRIVLRRAHVTLGAMEIFPCQRSSAWKWLRALSPIGTAEAHSEGSPRKLGTPYVVGLTLADGEALALGTLRPPPDSYCRVHLVFAPADADAEGLGTQPDMEGKTLVLEGERIPADGGPTVPFHLETSDVINAEVSLEGLTLSPESLEANRTLHLAYDQWLDGVDFVATGGSATNQILSNLARSVSLQP
>NZ_CP022098.1|WP_095987838.1|6603074_6603968_+|hypothetical-protein
MWKIRFALAALACFLLLFPREGLACATCACGDPTLTSMGTEQPFAGRLRLATQVRAWSLASGQPRVDNIDLRELRMDLSVAYAPLPWLFLSVMAPLQARSLQDVSLAREGGWGLGDMEVSARFFLFRDRDFSANHLVSVLAGSRLPTSVTQTARGLPLSLDAQLGTGSWDPFLGLSYTAYAGDWSFIASATGYLPTRGREGFRAGPSVLSTLAAQFQPSPAWALRLAVDGRVEGESNQAGVRDEVGSGAIAYVSPDVLFSPVTDVVVQLGVRVPVINQLRGNVRPTPILQAALVHDL
>NZ_CP022098.1|WP_095987837.1|6602204_6603017_+|siderophore-interacting-protein
MEPTERAGRRGPLPVKLRLLEVRRVTQLSPHMRRITVGGPELEGFQSPGADDHVKLFFAEPGQRMPSMPVLGPQGLTMPEGKPKPASRDYTPRRYDAARGELDIDFVLHDAGPASSWAAQAKPGDFLGVGGPRGTFFVANDFDWYLLAGDASALPAIGRRLEELPAGARALVFIEVADASEEQRFDTKAQASITWLHRNGAEAGTTNLLEKALREVQLPPGDGFTWVAGEANTLKPIREHLTQERGLRKEWTRVTGYWKRGVGDHHDSKG
>NZ_CP022098.1|WP_095992247.1|6601496_6601943_-|hypothetical-protein
MAAQFILPGGSSRQVAVFLAEATPARAGGERLSDLLNDSGSQFIPALDAETETMTFVHCENLAMARVAAEHEPNVVDPFNIPTEHEVEVRLTDGQRLRGLITYVLPEAHSRLTDYLNSAPSFFPILQEAGQVVLVNKKHVAYVETLRR
>NZ_CP022098.1|WP_157758674.1|6597656_6599009_-|hypothetical-protein
MTLDYFQGFLAQAGVPGTALPREGRTLAPQQALELVQHLLSTPVTLGNFGLRRMAAHLLLEVAASGEGVTRDELHARMRRFSRLLVLRPDGYLVRATTGVAVQQAGQVVLAEDGALRAGRFEVGPFYAIEGERLFPVNQQLEVPKGARPTGMYEPDDNPALAVAEGAVLAVVDMVEGLYRLVFYTGETLEGLAQLPGAVRQLYENSPQLWEEFRHKPYAAKVRTISRLSTGIVLTVGTTGAGAAKASSWGGKLGSMSVPLLSLSGDGLLAVRLVAVPVGGAVAVAGNALSATYVLHMANVGAQGGGGGSGWPPSGGPGKWEPANESMSEDSRCYQCQVTGAPPGWVYRVWRNGEKADFDGYSISEGVLQDGKAFSYAKHFDENLEPKEYFRGAKKMLETAKRQIRVADGVPIRWYVAEPEMVGILEKMIENAGLHGIEVVYQRASAGGVP
>NZ_CP022098.1|WP_095987835.1|6596940_6597660_-|hypothetical-protein
MTERYYAGVYWPARLESAEECARRSVAFFRLLAQCDEIYARWFEQGDSLEEALQRELTPDVGTFLRYFQCEENQLGKDGFSLGAWTGHAEAGHGGMVQLTCGDASGAYPNSCVLYLPRTDAEPEGARVLTAPVLVSVLRAMVLAWEPLFGVIATHEFRRALRPARDPRGFAGWLTYVARERGDVPPLPPPVRAEPVEDKGTVMVLAPERLSASNPEHLALGRRVQEVLDAKGLLRPVLS
>NZ_CP022098.1|WP_095987834.1|6596087_6596855_-|hypothetical-protein
MKDSREPPPVIYLSDRRPTLKDLPTFDPDRVPATAEAPSPDECLSEAELFQEIEVRQALLLERLIPLAAPAMKYFQLAPLRERLDFPGGSLEARRRALESRLGTPPDKVLREAWLDSPGYPLGMDSGLSVSGQPRCGSQSGVHLRRSLFLLPDETLAYFEEIGVWSSRGSDEYESSFTPMNARRIVVLDAVRLFPLHRLIAGLRGLLWFDRGAPQLPLEPGLEERRASFLSLVRDFFQATAVYNERLRQMALDSV
>NZ_CP022098.1|WP_095987833.1|6594557_6596078_+|MFS-transporter
MPLAVLHRHVLRSLAALASVVPFARPGAPPLASAPSTSTTAHVPSSHKARRRLRRSLRASVAEGIMAEVVTAGAGSTALTAWALALELGPFQVGMMTALPFFAQFVQFPAAWLTSTFGHRRMALSVVLVSRLMMLALCALPWLPLPLVGQQRLLMSVAGLWAVLGVIGNNAWVAWMGELVPESIRGRFFGRRTALCTLSNLIASLVAGVVMDRLRPATGVGPALPLLAAVSCAAGIVCTVLMARQHDPAPPGTREKPKLDLRVALVPLRDERARRVLVYQTFWNAAVGLSAPFYSFFMLQNLKMSFLLMSVQLAAVAAVRMLAAPLWGKLIDRLGAQPVVVLCSLILGLLPLVWLFPTATFLWPLILDALLAGVLWGGHNLAIFALPLAVAPRQGRPFYLAAFSTAAGLSYALASSVGGALASALPTEFTLGGHVWANLQVLFALSAVARLCAALLALRIIEPGVKSVDSLGALVALVRPSRREAPAVESRSASLSPLAEPVRVES
>NZ_CP022098.1|WP_095987832.1|6593374_6594379_-|polyprenyl-synthetase-family-protein
MELARELADFLGSVEQRLGTMLDDGDAGPDTQGDTLMEAARHLCLGAGGKRARPLLVRLFGGVFGVPPEKLLDVAVAAEMIHSSSLLHDDVVDAGMFRRARPTVNARWGNIVAVMSGDLILSTALFRLSHLDPRLTQSALAVVMEMSRAAIAEVESRGNLELSLERLRYVAEGKTGSLFGWCGHAAATLAGQPEAAERFDAFGRRLGVAFQIADDIRDVLGTDPGKPRYADVLSGTPSLPILLAVARDGSLRGKLKDAWAFTTINPERTRALGDAIERTDAVPLAVERMNAEIAAALEALGPYAHQGMGTELVRWARQLSEGITAQAEARSRAA
>NZ_CP022098.1|WP_095987831.1|6592805_6593378_-|MarR-family-transcriptional-regulator
MKGYLWTGGETGSGGPPVSGHLAPWEAVATDAVGNVIEFWGFKRNQGRVWALLYLRGEPLTAGELERELELSKGGVSMLLRDLERWGVVRRVRSPQDSAWRYAAETDLIRMVSHVVEEREASFIARIRADLLEARRLAEAQGLVPSERLARLEKMTTLAERVERALRLFIKTARLDVGGILDALREESNR
>NZ_CP022098.1|WP_095987841.1|6605625_6606561_+|ATP-grasp-domain-containing-protein
MSRDPQLAVVYEHPEWFKPLFAVLDRRGVPYVPLRIDQHYFDLNERKPPAPVIFSRLAMSSFLRQGEHAIFYTQSLYSHWEQAGARIINGNPALAVDTSKARQLSLINSLGYATPATRVVHRRADLVRAAEGLRFPIVVKVNIGGSGAGVVRYESAAELAQAVEERSTPDSIDSVLLVQEYVPTKERHIVRAETLNGRFLYAITVTTTGGTFDLCPADACMVGKPQVTLKQTTLDADTIHAVETISRAANMELCGIEFMIDERDGVRRFYDINGLSNFVAKPLEVLGWDPHEQLVDYLEGIVATARRGEAA
>NZ_CP022098.1|WP_095987842.1|6606557_6607592_+|LLM-class-flavin-dependent-oxidoreductase
MRYGFWAPVFGGWLRNVRDEGMEASWEYMSRLCRRAEEIGYDLTLIAELNLNDIKGVTEPALDAWSTAAALAAVTRRLELMVAVRPNFHHPALFAKQAANIDRISGGRLALNVVSSWWADEARQYGLQFDQHDDRYARTTEWLQVVDGLWSRTPFSFEGQRYQLKEAICEPKPLSSPRPLLYAGGESEAAKQMIARQCDAYVMHGDEPEVIAGKIQDMRARREREGLPPMRFGMAAYAIVRDSQEEAQAEVERITTLDPQAAGFANFEQWLSGTQLERELKIKEYSVSNRGLRPGLVGTPQRVRARIAEFEAAGVDLLLLQMSPQLEEMERFSSAIIAPERKAA
>NZ_CP022098.1|WP_095987843.1|6608572_6609358_+|ABC-transporter-permease
MNGSFARQVVPPLVALGVLLALWEGVTRVFGIAPWLLPPPSAIALAGAHEAPALWNAMFTTGRAALIGFGLSAGVGVLIAILLASSRLLERALYPYTLFLQTVPIVAIAPLLVLWFGPGTRAVAISSFIVSLFPVITNTLTGLRSVEPALRDLFRLYGAKRLATLWKLELPAALPQIFTGLRVASGLAVIGAIVGEFVAGFSEEGAGLGILVLTAYRQLRTDLLFASVLAAAVLGLALFGAVNLTGFRLLKRWHPSASSEP
>NZ_CP022098.1|WP_095987844.1|6609388_6610426_+|ABC-transporter-substrate-binding-protein
MKGRLAGVVGGLVLLVVAGACSRSKENAPQAAGGDAGSAAPQVAQVKLALNWVAEPEFGGFYAARDLGHYKRRGMDVSIQGGGAGVPVMQMVASGQVDFGIAGADEILTARARGVDVIPLFAVYQTAPQALMTHASRGAKGIKDLLSSGTVALEPGLPYAAYLKKKYGFDKVKVVPYDGGVARFVADKDFSQQCFITSEPIAARRQGADPSVFLVADEGFNPYIAVLITRRALWKEQPSRVKDFVEAVREGWRAYLDDPAATNAVMGKLNTSMDAETFAEAARAQKPLIETEQTRAKGLGTMSRERWDTLARQLVDLGLIDKVPASDDFLLPEFVDMGSPAPATP
>NZ_CP022098.1|WP_095992248.1|6610919_6611804_+|hypothetical-protein
MNEPEDSFYPYARLFARESLAVGASPVFYMTWSRKADLPAQEVLTRAYAHIAHEEGGVLAPVGVAWERARRERPELELYGEDGHHPGPAGTYLAACVLYASLFHQPCLGAPGTLSGAPWTGSAFDPSRTETLVELPEDTARYLQQVGSEVGLSPALPEGPTPTGPRLAFPQLPRGAPLDASRVAGTWRGMLSLYPTELEMAPVPMWLSVESRGTRLTGQVRILFPRDAPLEEDVTPRVEGEELTFSLHDARILGATLHLRAVRTEEGLCGVAHAQDAQGGRWFGSWSASPSSPA
>NZ_CP022098.1|WP_095987845.1|6611822_6612689_-|acyl-CoA-thioesterase-II
MSRVLEDLLELLKLEPIEENLFRGRSQDLGFRQLFGGQVLGQSLSAASQTVPPHRPVHSLHGYFLRPGDASLPVVYTVDRLRDGGSFTTRRVVAIQKGEPIFTVMASFQAEEPGFEHQAKMPEVPGPEGFPTDRELLGRKAHLIPEKIRDKLLCEKPIEIRPVTHLDPFDPHVLEPAKQVWFRVDGALPDDSRVHRYLLAYASDFNLITTALQPHGTSYMHPQMQLASLDHALWIHGNLRMNDWLLYSIVSPWAGNSRGLSYGHIFTRDGRLVASVAQEGLVRMRPPK
>NZ_CP022098.1|WP_095987846.1|6612797_6613433_-|protease
MTRGHVGWVALCCLALSGGGCTRRESAEGKPPEPAAPAQPSAPAEPSAQKPPETQAPEQKETPAMATTLECKLSVPASAPVGQPVELLFQLTNRTAAPLYVLSWRSPLERLGGRDFDITRDGAEVAYQGPMKKRAAPSPDQYLAVAPGATVEGRLDLAQAYDLSQPGRYRIVFPGPLMDVTDKLPDTARSFEVMTARPVTCAPVETTITRP
>NZ_CP022098.1|WP_095987847.1|6613543_6614647_-|peptidase-M35
MNQNVRGFKWLVGGVVGMSLLSACGAPMEGEDTSSALSDQALGDVAVSLSVASSSLSAREDVAVTVTFTNVSSQPVQLLRWYVPGTEGVKAGLFEVSRNGEEVAYVGPHVKRVAPRAEDFVTLAPGESRSGTALLSGLYDLSESGTYSVRFAAQSINQHNVGLTRAAALDSNIVNLWIEGRASREPEIQAQAVTAQGVTAASNCSSTRASQIATAFASAKTYASSTSTYLNGISSGTTRYTTWFGTYSSTNVTTARSHFTKISSAFASAAVTVDCSCTDSGTYAYVYPASPYKIYVCGAFWSAPNTGTDSRAGTLVHEMSHFTVVAGTDDHAYGQSAAKSLAKSSPTQALDNADNHEYIAENNPAQN
>NZ_CP022098.1|WP_095992249.1|6614929_6615562_-|glutathione-S-transferase-family-protein
MAHSPFARRTRLALAAKGLTVELRDVRAHPEFFEESRRLSPLKTVPVLVEEDGRVLGDSTAISHYLDRAYPSTPPLWPSEPDEALAAFEVASLVDLAINTAVDLGGRYHALRTSEAWETVRTEAMERMQRALDTLGQRAAALSRPTFSRRGWSAPDMWLFTAEHWFASLPARAPTFAPAAQICSLGWRLPPELSRWAEQHRDRPDVRALA
>NZ_CP022098.1|WP_095992250.1|6615635_6617012_+|amidohydrolase-family-protein
MKSHALLFSLLTAPLLASAAPAKTSPGAVVLRGARLIDGQGGAPIEDSVVVIQDGRILAVGPASSTTVPAKARVVDYQGKTLIPGLISNHSHVGQVQDANMGAGNYTRANISRQLRQYEAYGITTVLALGLNGPLLQQLRTQQHAGRGPGADLFGADRGIGVPQGAPPTLGGRPVGEDQLARPETAEQARQAVRDMVARKTDVVKLWLDDFGGSLSAKMKPDIYQAVIDEAHQRGVRVAAHIHDLEDAKMIVRAGADIVAHGVRDQPVDAELIQLMKERSVWYVPTLSLDEATFIYAERPEWMAEPFFQRAVQPALRARFADPAWVEKTRAEPKSEKARKDVAMNQRNLKALYDAGVRIGFGTDSGATPLRIPGVAEHRELALMTEAGLTPLQALTLATREAATLLALEDRGVLAPGKQADLVVLDGDPSTDISRTKTIHAVWHRGKQVSGTVDTFKP

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_18

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_18

8626065-8626148

Orphan

Consensus_repeat	Method
CCGGGATGGTGTCAAAGGACTCGAAACGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022098_18

>merge|NZ_CP022098|18|8626065-8626148|CRISPRCasFinder
CCGGGATGGTGTCAAAGGACTCGAAACGCGGGACCCAAGCCCCGGGATGGTGTCTCCGGGATGGTGTCAAAGGACTCGAAACGC

>NZ_CP022098|18|16|8626065-8626148|CRISPRCasFinder
CCGGGATGGTGTCAAAGGACTCGAAACGC	GGGACCCAAGCCCCGGGATGGTGTCT
CCGGGATGGTGTCAAAGGACTCGAAACGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_095992414.1\|8628822_8629035_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377437
NZ_CP022098.1\|WP_095992413.1\|8622141_8623035_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|377694
NZ_CP022098.1\|WP_095989127.1\|8629502_8630336_-\|DUF4846-domain-containing-protein	unknown	unknown	gnl\|CDD\|379777
NZ_CP022098.1\|WP_095989125.1\|8627119_8627908_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224117
NZ_CP022098.1\|WP_095989121.1\|8619599_8620382_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP022098.1\|WP_095989126.1\|8627911_8628505_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095989131.1\|8633405_8634734_-\|hydroxymethylglutaryl-CoA-reductase,-degradative	unknown	unknown	gnl\|CDD\|153082
NZ_CP022098.1\|WP_095989132.1\|8634781_8635873_-\|type-2-isopentenyl-diphosphate-Delta-isomerase	unknown	unknown	gnl\|CDD\|235465
NZ_CP022098.1\|WP_095989130.1\|8632448_8633399_-\|mevalonate-kinase	unknown	unknown	gnl\|CDD\|224493
NZ_CP022098.1\|WP_095989133.1\|8636206_8637154_+\|zinc-metalloprotease-HtpX	unknown	unknown	gnl\|CDD\|320695
NZ_CP022098.1\|WP_157758833.1\|8624128_8624227_-\|ATP-dependent-helicase-HrpA	unknown	unknown	unknown
NZ_CP022098.1\|WP_095989122.1\|8621005_8621965_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381329
NZ_CP022098.1\|WP_095992411.1\|8615446_8617606_-\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226654
NZ_CP022098.1\|WP_095992412.1\|8617777_8619094_-\|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl\|CDD\|226654
NZ_CP022098.1\|WP_157758831.1\|8623123_8623264_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095989129.1\|8631459_8632452_-\|diphosphomevalonate-decarboxylase	unknown	unknown	gnl\|CDD\|225941
NZ_CP022098.1\|WP_095989128.1\|8630380_8631460_-\|phosphomevalonate-kinase	unknown	unknown	gnl\|CDD\|224493
NZ_CP022098.1\|WP_157758832.1\|8623359_8623857_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340913
NZ_CP022098.1\|WP_157758834.1\|8624447_8625914_+\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|238624
NZ_CP022098.1\|WP_095989120.1\|8614970_8615450_-\|response-regulator	unknown	unknown	gnl\|CDD\|381106

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095992414.1\|8628822_8629035_-\|hypothetical-protein	gnl\|CDD\|377437	pfam04986, Y2_Tnp, Putative transposase. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases IS1294 and IS801. This is a rolling-circle transposase.	2.02322e-07
NZ_CP022098.1\|WP_095992413.1\|8622141_8623035_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|377694	pfam06719, AraC_N, AraC-type transcriptional regulator N-terminus. This family represents the N-terminus of bacterial ARAC-type transcriptional regulators. In E. coli, these regulate the L-arabinose operon through sensing the presence of arabinose, and when the sugar is present, transmitting this information from the arabinose-binding domains to the protein's DNA-binding domains. This family might represent the N-terminal arm of the protein, which binds to the C-terminal DNA binding domains to hold them in a state where the protein prefers to loop and remain non-activating. All family members contain the pfam00165 domain.	6.99644e-64
NZ_CP022098.1\|WP_095989132.1\|8634781_8635873_-\|type-2-isopentenyl-diphosphate-Delta-isomerase	gnl\|CDD\|235465	PRK05437, PRK05437, isopentenyl pyrophosphate isomerase; Provisional.	5.68739e-162
NZ_CP022098.1\|WP_095989125.1\|8627119_8627908_+\|hypothetical-protein	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	0.0040692
NZ_CP022098.1\|WP_095989131.1\|8633405_8634734_-\|hydroxymethylglutaryl-CoA-reductase,-degradative	gnl\|CDD\|153082	cd00644, HMG-CoA_reductase_classII, Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR). Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR), class II, prokaryotic enzyme is a homodimer. Class II enzymes are found primarily in prokaryotes and Archaeoglobus fulgidus and are soluble as they lack the membrane region. Enzymes catalyze the synthesis of coenzyme A and mevalonate in isoprenoid synthesis. Bacteria, such as Pseudomonas mevalonii, which rely solely on mevalonate for their carbon source, catalyze the reverse reaction, using an NAD-dependent HMGR to deacetylate mevalonate into 3-hydroxy-3-methylglutaryl-CoA. Human and bacterial HMGR differ in their active site architecture.	0
NZ_CP022098.1\|WP_095989130.1\|8632448_8633399_-\|mevalonate-kinase	gnl\|CDD\|224493	COG1577, ERG12, Mevalonate kinase [Lipid metabolism].	9.80987e-63
NZ_CP022098.1\|WP_095989133.1\|8636206_8637154_+\|zinc-metalloprotease-HtpX	gnl\|CDD\|320695	cd07336, M48B_HtpX_like, Peptidase M48 subfamily B HtpX-like membrane-bound metallopeptidase. This HtpX family of peptidase M48 subfamily B includes uncharacterized HtpX homologs and consists of proteins smaller than Ste24p, with homology restricted to the C-terminal half of Ste24p. HtpX expression is controlled by the Cpx stress response system, which senses abnormal membrane proteins. HtpX participates in the proteolytic quality control of these misfolded proteins by undergoing self-degradation and collaborating with FtsH, a membrane-bound and ATP-dependent protease, to eliminate them. HtpX, a zinc metalloprotease with an active site motif HEXXH, has an FtsH-like topology, and is capable of introducing endoproteolytic cleavages into SecY (also an FtsH substrate). However, HtpX does not have an ATPase activity and will only act against cytoplasmic regions of a target membrane protein. Thus, HtpX and FtsH have overlapping and/or complementary functions, which are especially important at high temperature; in E. coli and Xylella fastidiosa, HtpX is heat-inducible, while in Streptococcus gordonii it is not.	1.3726e-153
NZ_CP022098.1\|WP_095989121.1\|8619599_8620382_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	3.57031e-13
NZ_CP022098.1\|WP_095989122.1\|8621005_8621965_-\|aldo/keto-reductase	gnl\|CDD\|381329	cd19103, AKR_unchar, uncharacterized aldo-keto reductase (AKR) superfamily protein. This family includes a group of uncharacterized AKR superfamily proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance in both health and industrial applications.	0
NZ_CP022098.1\|WP_095992411.1\|8615446_8617606_-\|HAMP-domain-containing-protein	gnl\|CDD\|226654	COG4191, COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms].	6.45965e-27
NZ_CP022098.1\|WP_095992412.1\|8617777_8619094_-\|hybrid-sensor-histidine-kinase/response-regulator	gnl\|CDD\|226654	COG4191, COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms].	2.7516e-51
NZ_CP022098.1\|WP_095989127.1\|8629502_8630336_-\|DUF4846-domain-containing-protein	gnl\|CDD\|379777	pfam16138, DUF4846, Domain of unknown function (4846). This family consists of uncharacterized proteins around 260 residues in length and is mainly found in various Bacteroides species. The function of this family is unknown.	1.84884e-123
NZ_CP022098.1\|WP_095989129.1\|8631459_8632452_-\|diphosphomevalonate-decarboxylase	gnl\|CDD\|225941	COG3407, MVD1, Mevalonate pyrophosphate decarboxylase [Lipid metabolism].	2.22945e-86
NZ_CP022098.1\|WP_095989128.1\|8630380_8631460_-\|phosphomevalonate-kinase	gnl\|CDD\|224493	COG1577, ERG12, Mevalonate kinase [Lipid metabolism].	1.08768e-28
NZ_CP022098.1\|WP_157758832.1\|8623359_8623857_-\|MFS-transporter	gnl\|CDD\|340913	cd17355, MFS_YcxA_like, MFS-type transporter YcxA and similar proteins of the Major Facilitator Superfamily of transporters. This group is composed of uncharacterized bacterial MFS-type transporters including Bacillus subtilis YcxA and YbfB. YcxA has been shown to facilitate the export of surfactin in B. subtilis. The YcxA-like group belongs to the Monocarboxylate transporter -like (MCT-like) family of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.42652e-16
NZ_CP022098.1\|WP_157758834.1\|8624447_8625914_+\|amidohydrolase-family-protein	gnl\|CDD\|238624	cd01299, Met_dep_hydrolase_A, Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a conserved metal binding site, involving four histidines and one aspartic acid residue. In the common reaction mechanism, the metal ion (or ions) deprotonate a water molecule for a nucleophilic attack on the substrate. The function of this subgroup is unknown.	9.41827e-25
NZ_CP022098.1\|WP_095989120.1\|8614970_8615450_-\|response-regulator	gnl\|CDD\|381106	cd17554, REC_TrrA-like, phosphoacceptor receiver (REC) domain of Thermotoga maritima response regulator TrrA and similar domains. Thermotoga maritima contains a two-component signal transduction system (TCS) composed of the ThkA sensory histidine kinase (HK) and its cognate response regulator (RR) TrrA; the specific function of the system is unknown. TCSs couple environmental stimuli to adaptive responses. TrrA is a stand-alone RR containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	5.51484e-12

>NZ_CP022098.1|WP_157758834.1|8624447_8625914_+|amidohydrolase-family-protein
MPRYPVRYLFLALVLATWCLGCEDDPAAVDADYALTHVTVIDAAGTPPQSDMTLLIKGERIVALHKSDDVELPEDLKTVDLQGKYLMPGLTDMHVHTQELEQVFPLLHVVNGVTTLREMDGSPFLLEWRRRIEEGRMLGPRMILGSTIIDGTPSLWQNSPVPHVSVRNEAEGREAVRQARAQGYDFIKVYSRLSREAYFGIADEARLQQMPFAGHCPDLVTTAEASAAGQASFEHLYGVMYATSSEEAELRERVGEITLRPDTLTGYNTWFQQTHAVEWDAARTYSSAKGLQLFNQLARNGSAQVPTLVLHDVLDRSMDLDMDDARLKYLPASVVAGWRWQLAEIYLQDRSAEESEQRRDLFNHRLALVGQMHRAGVRVLAGTDSTTPWVFPGFSLHDELALLVQAGLTPLQAIQSATLEPARYLGMQDSLGTVEQGKVADLMVLDANPLDDIRNTTRIHSVVVRGRFISAEERREFLSDLETLAGSM
>NZ_CP022098.1|WP_157758833.1|8624128_8624227_-|ATP-dependent-helicase-HrpA
MGGVRAILEHLGLATAGAGLAPAHGPLQAAWC
>NZ_CP022098.1|WP_157758832.1|8623359_8623857_-|MFS-transporter
MSYAVTCGIPLMAAVSIYSMEGLAGMGGRLVFGLLGDRFGAARVLVLALLAQAVVVLGYVFARLLGSFYAVAALFGFTYAGVMPLFAVIAREHFPLRMMGTVIGGTTTASSLGMALGPVVGGLIYDSTSSYAWLFIGAFSLGIGAFLSALAFTRLPGRRTMVALA
>NZ_CP022098.1|WP_157758831.1|8623123_8623264_-|hypothetical-protein
MSVFNVWSAGDALPLAAKHCRAHGKDAVFDRMSFITAHFKCESSAK
>NZ_CP022098.1|WP_095992413.1|8622141_8623035_+|AraC-family-transcriptional-regulator
METLIEIAAVIARHVSKDGFHATPIERLTLARSSTVTLPMPNVYRPQLCLVAQGHKEVTLGDRVFRYAPGRYGIVVHDLPVTGHVVEATPDKPYLCLFLDFDPVMLGELALRVPPPGASCPPIGMTVSDVGTDLLDAVLRLLRLLDDPAALPILGPLAEQEILYRLLAGPDGARMRHITSSQGRVAQVGRAIGWIGKNFREGFRIERLAAEVGMSPSSLHEHFRAVTAMTPLQFQKQLRLQEARSLMLVDDIDVTTAALRVGYESPSQFSREYRRHFGEPPARDIARLRASTALAQA
>NZ_CP022098.1|WP_095989122.1|8621005_8621965_-|aldo/keto-reductase
MTIDNLKTPTVALGTWAWGDSGETGNGYFGSHLTPSGLEKVADKAHAAGFTLWDTAVVYGMGRSETVLGDVLKRYARSDYQLSTKFTPQAAGTGEDPVADMLEQSLARLGTDYIDLYWIHNPADVARWTPHLIPLLKSGKVRHVGVSNHKLSDIELANQILGAAGFRVEAVQNHYSLLYRSSEQAGILDYCRKRDIPFFAYMVLEQGALSGKYSPENPLPQGSDRAKHYNGLLPQLKALTDKLASIGQKQGVAAPEIATAWAIAKGTTPIIGVTKPQYIESLVRANSITLTREDMAELESLADAADVNTRGWWEQEMSV
>NZ_CP022098.1|WP_095989121.1|8619599_8620382_-|alpha/beta-hydrolase
MDKVTSKDGTSIAYEKTGSGPALILVDGALCYRAFGPMPKLSPLLARHFTVFTYDRRGRGDSGDTQPYAREREIEDLAALIEAAGGSAAVAGLSSGAALALEAAASGLNITKLTAYEPPYVSAASGRLEADHEANLKRLLSEGGRGDAVQYFMRDMMGAPGFVVLLMRLMPGSWRQLQAVAHTLPYDANVMRGYSVPTERFSSIRVPTLVMNGGKTDPRLKQAAEGVAKAVPNAQHRTLAGQTHNVSPKVLTPALVEFLT
>NZ_CP022098.1|WP_095992412.1|8617777_8619094_-|hybrid-sensor-histidine-kinase/response-regulator
MSLSAVPAPRVLVIDDTPSIHQDFHRLLAESEGGASLAELRASLFGMPPPRPKGYCFEVDSAFQGEEGLQRVKVALKEGRPYALAFVDVRMPPGMDGVETTERLWREDPDLQVVLCSAYTDYSWEEVVQRLGISQRLLILHKPFQSMEVRQMAHALAEKWELLRRERRRVAELEQANAQLRRETEERRLLEFKLVQAQKLEALGRLAAGLAHEVNNPLSFIIANLHHVRGELKALAATQPPRDVEELQESCHDALQGCERIQRLVQDVRGFSRGRSFPDAPVALDTVLEDALAMANLAQVPGLRVEWARCPVPPVLADEHGLGQVFLNLIINALHAVAKGPAEPRLRVATGLLADGRVWAEVQDNGHGIAPEDLGRIFEPFFTTKPPGVGTGLGLFICHGLITGFGGELSVESQPGQGATFRVLLTAAPADAPSSAVA
>NZ_CP022098.1|WP_095992411.1|8615446_8617606_-|HAMP-domain-containing-protein
MVIALSTLFSYLHLFKTLRDQFLLQLERSVVERGHREESIFLLAEDHHAFLKKALQERIQSLSQEEAASRFERLTVQLPDGTIRSRPEGFDGTKMPGFMVFRGVSPNAELRQRLVAAYDVLVQHGPLLLTRVEDTYIMMPEGAFVTLWPERPTYTQDTEPDFPLYTFDYFTNSLPQNNPQRRTAWSGAFLDSVSKVWMVTASTPLDVEGRHVATIGHDLLLNELMARTAKGHLPGSYNVIFRDDGQLITHPELKLDGTEAYNIRDVSLSGGFTPFGSPEQRAHLRHIFERVMARASGQSVLELPEHGEFLATIRLGGTGWNFVTVLPGKELTGPALLAARYVLVFGLAALVLELAIMFWVLREQISRPLLDFTHATERIATGNFQVQLDTRRQDELGQLAWSFRLMADEVQRREEALRQANEGLEQRVDERTRELKDVHRQLVQVARQAGRAEVATSVLHNVGNVLNSVHTSAMLAKERLVGLQVDDVSQLATLLEERRDDLATFLTQDERGRNVMPFLSGLGQHLRKETHEAVSLLDEVGRYTEHIGTIVKLQQNYTRTPRLNEPAHLVELLEDALRINSAGLTRHEVRVVRHLSPVPQLLTDKHKVLMILVNLISNSKYALDAAPAEQRCLTLRVEAPAADRVRIEVSDNGMGIAPELLTRIFQHGFTTREEGHGFGLHSSALAAQELGGTLTAHSDGLGRGATFTLELPCTPPEAA
>NZ_CP022098.1|WP_095989120.1|8614970_8615450_-|response-regulator
MSDKRRILIIDDSAAIHQDFRRLLCPERGGSPEQLASLRTALFGAPSARARPAGPEFEVESAFQGQEGVARVREAVAAGRPYALVFLDYRMPPGGNGVETLRELWKVHPSQRVVLCSAYSDYSWEEIVEEFGETPLLKELRKPVNGHELRQLALTLTEP
>NZ_CP022098.1|WP_095989125.1|8627119_8627908_+|hypothetical-protein
MTQQVLLDVPDAKLTQYIDQSSHPYVQQNGGVCSAMTLHWIDQSSQHSSPSEASAHFGKTLNNNINDIISDQQHIETEISSLSNKLNHAENYLDTVLTQEQQTINQKKKLAKEGKLSPEGLQDLEKHRQWFRSELAGVKQAMAETSAKQQELKSNLGAGLPHTNMANKEPLNPDTFGEHVAELIGGNNGFYRLSFNGAEGEHGHVVGLQVSHDTGEYKYMDPNTGEFRMNDPTDMLNVAILHANKLNYHKDYSSFSLDHYAH
>NZ_CP022098.1|WP_095989126.1|8627911_8628505_-|hypothetical-protein
MTTIRYFRLTDRKDIPGRWLLSDPIDAKGQPIDDPLHFAQGLPVPAGARYRIAVERPGKALDFSLPSAGVTPIVHKKVATLFTELAPGDVQAIPVDINGQSEPYFILVATRNVRCIDDRACEKVEFWKPEDGEKELVGQYRSVVGLRIDPAKVGGVQVFRPWGWTVALIVSETIKTALERARVSGMAFKEVTGSKPG
>NZ_CP022098.1|WP_095992414.1|8628822_8629035_-|hypothetical-protein
MLFTGLELLRRVASLVPPPRANLTRFHGVFAPGAQLRPFLVPQAGAEEASVAPQAAASKEPIKEKTSRVD
>NZ_CP022098.1|WP_095989127.1|8629502_8630336_-|DUF4846-domain-containing-protein
MSALLLGACLAGASEPRAPTRQERARYPWLSADSSIRPLAEALPPPRGYTRVALEEGSFGAWLRGLPLRPEGTPVLDFQGRTILAAKDASLAAVAELNVGRADLQQCADSLIRLHAEWLWSRGDKERIAYRFTNGDLASWPRYAQGERARVSGSKVTWVKSGPVDGSRAAFQKYLDLVFTYAGTLSLAAGKRRPSREDVRPGDFFVLGGSPGHTVMVLDVARDAEGRRVALLGQGFTPAQDFHVLSPGDAGPWFSLEGDTVATPFWAPFPWSSLRRW
>NZ_CP022098.1|WP_095989128.1|8630380_8631460_-|phosphomevalonate-kinase
MERALSAPGKLFVSGEYAVLWGGLSRVAAVGPRTAALVRRRADSQVHICLEEGTLAGRTTSRGVKWEREVPPGFSFVARTLDEALRLHGRESVGFDLALAPSAVGPNGLKLGMGGSACATVLAADAVRFVLEERFDALKLALVTHAAAQGGKGSGGDVATSHAGGVVRYRRYEVSGLIEASSAGGYRAAVDASPPVDVWRLPTPRVSLGYAFTGESASTRVLISQVEAKWGEQGRRSFVERSDALGQEIEEGLAGGDFRSFSEAVREQHALLQELGPLETEPMKRVLGLAASYGCAGKQSGAGGGDGCILFAPDAEQRAALLEGIRARGFHTLELTVEPGVRSEAVADSRLRAWLDACS
>NZ_CP022098.1|WP_095989129.1|8631459_8632452_-|diphosphomevalonate-decarboxylase
MKATALAHPNLALVKYWGKRDDALILPHQSSLSLTLSPLSVHTTVAFGVGNADAVELNGYVAKGSERDRVLRVLDAVRAEAKERSLGPARMVSRGDFPASAGLASSAAGFAALAVAARAAAGLPADPRASSLLARLGSGSACRSVQGGLCEWMRGERPDGSDSYAVQRFDEKHWPELRMVVAIVSRDEKEVKSRDGMKNAVETSPYYAAWIKDAEAEVVRARDYLARKDLQALGEMCERNAWRMHATSLAADPPLCYLMPGTLALIHSLREQRKKGVPVWFTLDAGPNPCILTDAAHEVAAEAVARACGATEVVRCVPGGDARLLTEHLF
>NZ_CP022098.1|WP_095989130.1|8632448_8633399_-|mevalonate-kinase
MDSNNTLVGFGAGKVILLGEHSVVYGYPALAGPLSRGVTARGEASNKCQLVIPEALTPEQRKVLKAAFGRAMAACDEPGVRVSFNTDLPLSMGLGSSGALSVACARVLLQAAGRKATAMDVANVAWEMEQEFHGTPSGVDHTTSAMEQLILYRRKPGAESGRSKVVESPKPVRLVVVMAGARSPTKTTVGALRERQKRWSERYQRVFREIGLLASEGAEAVEEGDLEALGDVMNVNHGLLAALGLSSPGLDDMVHRLRTMGALGAKLTGAGGDGGAVIGLFHDTAPAVHELTRQGFRCFDSQLAGPREEGATRGAA
>NZ_CP022098.1|WP_095989131.1|8633405_8634734_-|hydroxymethylglutaryl-CoA-reductase,-degradative
MSDTLTSRLAGFHKLSMVARHEKLAEMLNLTEEDLAQLQGISALQPGLANQMIENAVGTFSLPLGLGLNLQVNGKDYLVPMAVEEPSVVAAVSFASKIVREAGGFTAETDEPIMIGQVQLTRYGDPTEATQKIHAAREAILALANSFHPSMVKRGGGCKDIEVRVLPAPEGPRGEPLLVVHLVIDTQDAMGANLINTMAEGVAPLLEQLTGGKVYLRILSNLADRRLARAMCRIPLEALSDFDMPGATIAEGIYQASRFALADPYRAATHNKGIMNGIDSAAIATGQDWRAIEAGAHAFACRDGQYRPLSTWHVEGGHLVGRIELPMALGTVGGPIKVHPGVQIAMKLVNVTSARELSMVFAAVGLAQNFAAVRALGSIGIQKGHMALHARCVAVTAGARGDWVEKIAELLVTAGHVKVEKARELIASLSEEDFRAATGTEG
>NZ_CP022098.1|WP_095989132.1|8634781_8635873_-|type-2-isopentenyl-diphosphate-Delta-isomerase
MVPPNEGRRHVTDEEATAKRKDAHLDLCATGDVEPLGNSTLLEDVRLVHCAMPELSVDEVNLSTEFLGKTLRYPLLITGMTGGTERAGVVNRDLALVAERHGLAFGVGSQRAMAENPQAAESFQVRRVAPTVPLLGNIGLYQAVRMGVDGVRRLADAIGADGMALHLNAGQELTQPEGDRDFRGGYQIVEQLVRAFGARLLVKETGCGIGPDVARRLVELGVRNVDVSGLGGTSWVRVEQLRAEGVQAQVGAEFSNWGIPTAAAIASVRRAVGSGPRLVASGGLRTGLDAAKVIALGADVAGMALPLFRAQQAGGVEGAEKALAVILSSLRQAFVLTGSASCADLQRKPRIIGGQLKDWLATL
>NZ_CP022098.1|WP_095989133.1|8636206_8637154_+|zinc-metalloprotease-HtpX
MRNTSLPPMGTGGGGWGHRLGNALKTTVLLAGLTALLLVVGERLGGPQGLVVAGFFVVVMNFVSYWFSDRIALAMHGAQPLEYAEAPWLHAMVERLAARAGMPKPAIYLLPTRTPNAFATGRNPEHAAVAVTAGLMDILDQRELEGVLAHELAHVKNRDTLIGTVAATLAGVISYAAQMLFFFGGSLLSRDDDEDGLAHTLGNLGVLLVAPIAATLLQLAVSRSREYGADATGAQLSGDPDALADALLKLERGAELMPYDRAPATSHLFIVNPLSGGAIMGLFSTHPPIPERVRRLREMSALTPRSPRAWRSVWA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_19

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_19

9631728-9631877

Orphan

Consensus_repeat	Method
TGTGCTTCCAGCTCCGCGATGCGG	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP022098_19

>merge|NZ_CP022098|19|9631728-9631877|CRISPRCasFinder
TGCGCCTCCAACTCCGCCACTCGGCGGGTGAGCGCCTTCACCTGTGCTTCCAGCTCCGCGATGCGGGCATCCCGCGCGGCCACCTGTGCTTCCAGCTCCGCGATGCGGGCATCCCGCGCGGCCACTTGTGCTTCCAGCTCCGCGATGCGG

>NZ_CP022098|19|17|9631728-9631877|CRISPRCasFinder
TGCGCCTCCAACTCCGCCACTCGG	CGGGTGAGCGCCTTCACC
TGTGCTTCCAGCTCCGCGATGCGG	GCATCCCGCGCGGCCACC
TGTGCTTCCAGCTCCGCGATGCGG	GCATCCCGCGCGGCCACT
TGTGCTTCCAGCTCCGCGATGCGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_095992495.1\|9619750_9620431_-\|PIG-L-family-deacetylase	unknown	unknown	gnl\|CDD\|376836
NZ_CP022098.1\|WP_095989796.1\|9627138_9628311_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225814
NZ_CP022098.1\|WP_157758912.1\|9639258_9639552_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095992494.1\|9616306_9617491_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|271320
NZ_CP022098.1\|WP_095989802.1\|9641752_9642352_-\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|283141
NZ_CP022098.1\|WP_002632398.1\|9623784_9624834_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_071905527.1\|9643097_9644165_-\|acyl-CoA/acyl-ACP-dehydrogenase	unknown	unknown	gnl\|CDD\|224871
NZ_CP022098.1\|WP_095989801.1\|9641102_9641756_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|366154
NZ_CP022098.1\|WP_095989800.1\|9635322_9635934_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095989798.1\|9629770_9630412_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095992497.1\|9636743_9639035_+\|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|276965
NZ_CP022098.1\|WP_095989794.1\|9619301_9619754_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|283141
NZ_CP022098.1\|WP_002632396.1\|9620985_9622785_+\|amidohydrolase	unknown	unknown	gnl\|CDD\|224490
NZ_CP022098.1\|WP_157758913.1\|9645609_9646005_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|366154
NZ_CP022098.1\|WP_095989795.1\|9625959_9627132_+\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|235167
NZ_CP022098.1\|WP_095992495.1\|9642348_9643029_-\|PIG-L-family-deacetylase	unknown	unknown	gnl\|CDD\|376836
NZ_CP022098.1\|WP_157758911.1\|9632218_9633349_+\|DUF4209-domain-containing-protein	unknown	unknown	gnl\|CDD\|372806
NZ_CP022098.1\|WP_081713719.1\|9622807_9623755_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182137
NZ_CP022098.1\|WP_095992496.1\|9633908_9635315_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095989797.1\|9628307_9629078_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225818

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095992495.1\|9619750_9620431_-\|PIG-L-family-deacetylase	gnl\|CDD\|376836	pfam02585, PIG-L, GlcNAc-PI de-N-acetylase. Members of this family are related to PIG-L an N-acetylglucosaminylphosphatidylinositol de-N-acetylase (EC:3.5.1.89) that catalyzes the second step in GPI biosynthesis.	1.78847e-26
NZ_CP022098.1\|WP_095989801.1\|9641102_9641756_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	6.74651e-16
NZ_CP022098.1\|WP_095989797.1\|9628307_9629078_+\|response-regulator-transcription-factor	gnl\|CDD\|225818	COG3279, LytT, Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms].	6.49139e-56
NZ_CP022098.1\|WP_095989802.1\|9641752_9642352_-\|methyltransferase-domain-containing-protein	gnl\|CDD\|283141	pfam05401, NodS, Nodulation protein S (NodS). This family consists of nodulation S (NodS) proteins. The products of the rhizobial nodulation genes are involved in the biosynthesis of lipochitin oligosaccharides (LCOs), which are host-specific signal molecules required for nodule formation. NodS is an S-adenosyl-L-methionine (SAM)-dependent methyltransferase involved in N methylation of LCOs. NodS uses N-deacetylated chitooligosaccharides, the products of the NodBC proteins, as its methyl acceptors.	1.53256e-10
NZ_CP022098.1\|WP_071905527.1\|9643097_9644165_-\|acyl-CoA/acyl-ACP-dehydrogenase	gnl\|CDD\|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	1.04622e-10
NZ_CP022098.1\|WP_095992495.1\|9642348_9643029_-\|PIG-L-family-deacetylase	gnl\|CDD\|376836	pfam02585, PIG-L, GlcNAc-PI de-N-acetylase. Members of this family are related to PIG-L an N-acetylglucosaminylphosphatidylinositol de-N-acetylase (EC:3.5.1.89) that catalyzes the second step in GPI biosynthesis.	1.78847e-26
NZ_CP022098.1\|WP_095992494.1\|9616306_9617491_-\|hypothetical-protein	gnl\|CDD\|271320	cd05819, NHL, NHL repeat unit of beta-propeller proteins. The NHL(NCL-1, HT2A and LIN-41)-repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures. The repeats have a catalytic activity in Peptidyl-glycine alpha-amidating monooxygenase; proteolysis has shown that the Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) activity is localized to the repeats. Tripartite motif-containing protein 32 interacts with the activation domain of Tat. This interaction is mediated by the NHL repeats.	6.58549e-19
NZ_CP022098.1\|WP_095989796.1\|9627138_9628311_+\|sensor-histidine-kinase	gnl\|CDD\|225814	COG3275, LytS, Putative regulator of cell autolysis [Signal transduction mechanisms].	3.20149e-40
NZ_CP022098.1\|WP_095989794.1\|9619301_9619754_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|283141	pfam05401, NodS, Nodulation protein S (NodS). This family consists of nodulation S (NodS) proteins. The products of the rhizobial nodulation genes are involved in the biosynthesis of lipochitin oligosaccharides (LCOs), which are host-specific signal molecules required for nodule formation. NodS is an S-adenosyl-L-methionine (SAM)-dependent methyltransferase involved in N methylation of LCOs. NodS uses N-deacetylated chitooligosaccharides, the products of the NodBC proteins, as its methyl acceptors.	4.90773e-08
NZ_CP022098.1\|WP_002632396.1\|9620985_9622785_+\|amidohydrolase	gnl\|CDD\|224490	COG1574, COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only].	3.7855e-117
NZ_CP022098.1\|WP_157758913.1\|9645609_9646005_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	7.83846e-16
NZ_CP022098.1\|WP_095989795.1\|9625959_9627132_+\|acyltransferase-family-protein	gnl\|CDD\|235167	PRK03854, opgC, glucans biosynthesis protein MdoC.	6.00309e-21
NZ_CP022098.1\|WP_081713719.1\|9622807_9623755_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|182137	PRK09906, PRK09906, DNA-binding transcriptional regulator HcaR; Provisional.	1.699e-46
NZ_CP022098.1\|WP_095992497.1\|9636743_9639035_+\|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|276965	sd00038, Kelch, Kelch repeat. Kelch repeats are 44 to 56 amino acids in length and form a four-stranded beta-sheet corresponding to a single blade of five to seven bladed beta propellers. The Kelch superfamily is a large evolutionary conserved protein family whose members are present throughout the cell and extracellularly, and have diverse activities. Kelch repeats are often in combination with other domains, like BTB and BACK or F-box domains.	1.4444e-28
NZ_CP022098.1\|WP_157758911.1\|9632218_9633349_+\|DUF4209-domain-containing-protein	gnl\|CDD\|372806	pfam13910, DUF4209, Domain of unknown function (DUF4209). This short domain is found in bacteria and eukaryotes, though not in yeasts or Archaea. It carries a highly conserved RNxxxHG sequence motif.	0.000562317

>NZ_CP022098.1|WP_095989798.1|9629770_9630412_+|hypothetical-protein
MTRTAEILGSEFDAPAQLPERLEHYEPKRGLALAALKRAEAEGDSAAVEVMYWELGLLDLWLSPAKDVSPYFGGTYQAYAEHYRISERTMAYGLERSKETRDIILKLHYLTFVLLRSEPRGKTWMELQRELLTSYREYVSGCLQGRKSAPAHTIGVWIEGALSAAGPLMARPGIIRNDAYAEWAQWIFGLAEESLTFPREEKKEYAFTGSGRR
>NZ_CP022098.1|WP_095989797.1|9628307_9629078_+|response-regulator-transcription-factor
MTTPLSVLVVDDEAPARAKVKRFLADDARFTLAGEAQDGAEAVARIEALKPHLVLLDIQMPGLTGFEVLETLGPEHCPEVIFSTAYDQFALKAFDAHAVDYLLKPYDAERFRRALDKAWTRLDEGRTDTERLKALLSSLEPPREKPLERLLVKTGEAWVALRVDRVSRFSAEDKYVRVFSDEGQHLVRQTLKHLEERLDPRRFVRVHRSELVNLDAVVRLEPWSHGDGLLMLRDGGSVVLSRTYREAFLERWGVEG
>NZ_CP022098.1|WP_095989796.1|9627138_9628311_+|sensor-histidine-kinase
MEATPTRQPALESRPWRWPVLRAREALALLGFGVAVGLWLGSTVWLTMRADGSTVPWTRPFLWELTGALAAFPLLPMVQTAILNAPSPRASGRSRGAAWGRFLGIHLGTWLLYTSLHILLMVGSRNLLYALLGWGSYDYGHLGFRVPMEAQKDLIVYVLAYAGLTVYAAWKERQENALREARLEGQLKAAQLRTLMGQLNPHFLFNALNTISSVMYEDLAKTDRLLSDLGLLLRESLERGTGPTWPLADERKHTERFLALMQARFGERLRVRWELEPGLEPLPVPRFALQLLVENALKHNQEQLTGLEVRLRAWSEGGALLLEVEDTGRGLARPSLATHGAGLGLTGLRQALELLHGPEGHLELGAGPEGGARVRIRVPVTRARSEEALP
>NZ_CP022098.1|WP_095989795.1|9625959_9627132_+|acyltransferase-family-protein
MNPIPRPATERRPDLDWLRVVAILLLHLFHTGMMFNSWDWHLKAPELLPVLEPPMEFLHHVRMPLLMLISGAVTAMALRRRGLGAFVWDRTKRLLWPLVFGIFVIVPPQIYAERLFRGTFHGGYLDFYPSVFQFVSYPAGSFSWHHLWFVAYLFIYCLLAAPLFAWLETARGRAFFERAEAWLARGWNPWLLFLPLALGRILLRRFPETHALTDDPNTFVYYGQLFLLGHILGRGSRLQERLVVMRHRSLAISGVLFALMVPSFEYPFPFEHLGTYALVWCLLLTALGYARAHIPTRSAWVTYAQELAYPFYIFHQTVIVLVGFALLRPAVGPWTRFGLVLTLSFLVTWALCECVKRVPWLRPCFGMAGRKPVAPGAVPTPSPLEARSGA
>NZ_CP022098.1|WP_002632398.1|9623784_9624834_-|hypothetical-protein
MLTQIDLNIAPDTRFLSTLEWRGWSPDGQMLWQHRAPGVAPNVRNGEFPWYYEVHPRGEGFLIVNSWEREYGTTSIDFGCAEVLDGKQANRLLLMDGQGACTRSLGIEYVPTGVATSGEDFWISRCLYHGAGVQWPSMQRRDAMNQVLTDVMVNPPPPYLTHVSQSTLLSWGDGKLSRRSESFEPLWSHVLPIFGQENPAELPDGQLGVVGRRSRSEGFTFGTSVIPLGDDFVMVRFSGQGKPLGAVATGIPTREIPGQPRAITTDALGMIVAGGEANSVVALSWTGSKQWERAVKDMVPELCLPKVHSVASHARYGVRVVGLGYVPAVDGTCEETPQSQRIFVMALTR
>NZ_CP022098.1|WP_081713719.1|9622807_9623755_-|LysR-family-transcriptional-regulator
MPFGYAAIMELRHVRYFAAVAEQISVTRAAQLLHVSQPALSRQIRDLEEELGVDLLERYPNSIALTEAGKVFLAECKVILRRVEDAVEKVRRKSPSHRSILRIGFAATPAVEILKQAMRVFHKQHPSIQIELKDLSSNGIVRGVRDLKLDLGITIGVAPQSFEGLAMKELGSYGVTVAFPKEHRFAKLKQVPLAEVAKEGLITFTKSEHPEAHSAIRKILSGFTEEPNIVMECDGISSLFAAVESGKGVAIGFETMAKLAGSRLNFRPVLPAPPRLPVVVIYDQAKLSSAGTDFLATLAAVKLKSLRPAAGLLIV
>NZ_CP022098.1|WP_002632396.1|9620985_9622785_+|amidohydrolase
MSALRLLALSHLLLAGLPARGDELRPGADLIVFNAKITTQHLAQPAASAVAIKRGRIYAVGDDAEILALKNSKTQLIDAEGHRLIPGLNEAHVHVLNENNYNYNVRWDGVPTLSRALEMLKEQAKRTPKGQWVKVIGGWSPYQFKENRFPTPEELNAAVPDRPYIVQYAYNQAFLNELAMKEIGVGTPKFQMPPGTEFEKDKQGKYTGVVRGFTWTFVALEAVVPLPSFEEKVNSLAYAINDLNRFGVVSALESGSIIPYPEGHKPIEALIKDQRLNVRLPFMDLQLVEPGASMVDAEIDAITQKSPTSPGDNTHPTLAHGHEYQTNGEVLNAQLHDHENFDRPAVVIDRELMRKTVEEDVGKLVKRRSPFRMHVSYDENISPFLDALESLNKKMPFDGLRWSIEHAETISPKNIERIKKLGGGIALDDKMALHGDGFIKTHGREVALQTPRLRQLVDSGIPLAMTTDGFRASSYNPWVAIQWMVTGKSVSGSEILAKDNRLSREEALKLYTLGAAWFTKTENESGRIAPGNLADFALLSTDYFSVPEGEIQHITSVMTVVDGKVVFGAGKYSKLAPELPKIIPTWSPIKYFGGYSGAK
>NZ_CP022098.1|WP_095992495.1|9619750_9620431_-|PIG-L-family-deacetylase
MPSLEPALLVPEGRRAVIVAPHPDDEVLGTGGLLARLGRLGRDVLVLAVTDGTASHPGSTSWPVERLARTRPRETQEALQRLGLGGARVERVGIPDGAVTENEERLVEWLGARLRPDDVVLATWRLDGHPDHEAVGRAASRACAALDGRCVEFPIWMWHWARPGDTRVPWSRARRIELDEATLALKRRAMEAYVSQLEPDSTTGNPPIVPPYALERLMRPFEVVFT
>NZ_CP022098.1|WP_095989794.1|9619301_9619754_-|class-I-SAM-dependent-methyltransferase
MSVPMAHFERMYADSEDPWEYRRRWYERRKRALTLAMLPHARYARAFEPGCSIGELSAELAARCDALLVGDGSEAAVRVARRRLAPWPHVRVEQRLLPDSWPEGTFELVVLGEFGYYLPGGASRSSPPHLLGGAEMAALSRLERRRHETS
>NZ_CP022098.1|WP_095992494.1|9616306_9617491_-|hypothetical-protein
MPASTPGKVTVTGPGGPQELTSSRTLTVTSGSYTLTAGIVAASHPLVRTAFRADATPNPVCVHEGQNTTVAVAYAPIGSSGKLWTSNGSGGSAPLLGFSADVLGTSGSPAATVAATTAGAEGSAFDREGNLWVVGATAADPPVLRLPASALGTSGRKTADISLTDGPLEGGFPRARALAFDASGNLWVSVVFNNKIVRYTSEQLATSGSPTPSVEFSGLEGPSGLAFDSAGNLWVAFMGADRVARYNASRLGASSMASPDLVIEAQTPPPVIGTLRAPTGLAFDVSGNLWVNFNGTLTRLTPGEQVGSGSITVTPTVQVGLSVTALPDGLVFDESGNLWFALSAGQFGRLGPSQLTSSGSKTPEVIITSPDVAYTGWFSLYPAPAGLPLYHRLP
>NZ_CP022098.1|WP_157758911.1|9632218_9633349_+|DUF4209-domain-containing-protein
MFYEADPLADRGSIRVAEAEAKLRKHWGEKGDKVHERKVRRTFDAIVRRAEFFQKTGNGSITAGVFREARQLVERERRFFTADDIARLQGAEQAALNRALEAGEFVPFTVSLKVPSQFMDYTQETPEKTAVELAEQAVREIPNRKEIAENVKETSAQTPLLAMVKRTLISPGKVVGESNSLQTNLDRDIENRAMSQASLFGAAVSITAARAAKTVGLTEEHLIIPLHPLALDEDSLLFIRRGCERLIAQDFISATHILILRVEDVLRRHLRRLGVDTTEFKADVGDGTSRTDDVPFGKLMRLTLSDGRTVKDYLGSDLWEHLDSVLNSQTGLNLRNEIAHGLARPQHCTAESAGIALALLYQLAFTVWLASQSETD
>NZ_CP022098.1|WP_095992496.1|9633908_9635315_+|hypothetical-protein
MLVVYAAEVEARGSTRVVAVTREEYQRAVAHLLQRHQVHGTPQEAAQGLLQAMPEEELLAEVYRDKVLTLVPLNDKGTLVPEAEAALKAKYLRWCQPRGGGDCLGLFTDGPYLRTDDRRTLALALAFGGVLDETRAALGRELSPQALLSSLVWAAGLYLALWLLPEPSTKAAAAALSVVLLAWLGVDALWGLMDGWASMAHAAHEATTFEELRDAGEAFGKRIGTHAARALILSVATLTGRTLGEVATHVRSLPRFNQVQAQWAAQGMEGSVAVAMEEAAAVEVVVEQGRALVVLTSPQAAVAINVLARSGSSRASGGHSGTVAIRHRGGNMQVILSNGERWHLPRGKSYRDIPAKDRLGDELQAAVKEFAAKWSQAFLRDEERRAIDAVRSRGLEYRANLLERQARGRWVELQMKQRFPSLSWNSRGVDITGPGGQSYHYEILSGTESNFALHGRRMASTFFRMIFF
>NZ_CP022098.1|WP_095989800.1|9635322_9635934_+|hypothetical-protein
MTPNIHYEKREIVGERLELAKGPIYWLGPDLTVRDSTVIISAAGRSVVPMSGQFINCTIQAKGQLTGLPWAPMKLTGCRFKGRFTGNDFGFREDVDERWKGGGIEDCDFTEAQLNGCRFFNCDMGTIRLPRWPCFSFLDARGHAAELARRAWPGSFDSVVRTVCDPPKGTVASVWHAHTVAKKSDTTVEELRAALETAPGIFM
>NZ_CP022098.1|WP_095992497.1|9636743_9639035_+|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein
MLALFAGCRSSEPPAVSATGSVSLVASTGQALAVSDIARVTVTTSAADMPTITIELAQIDGAWGGVIGDIPSGTNRTFLAQAYDSTGTLRYEGRVENVTVRAGVLTLVTLTLQNVSPSTPFTNEAPIIDSVTATPLVVAPGASVTLVASAHDPNPGDTLTYSWTAASGSFSAPSKPSTNWTAPATTGPVSLRLTVSDSRGAASLVTLMVRVSAGEGGAVVDVSFNNPPKVISLTSSQSYLDVGQQTTLSTSVSDADGDSLSYTWSATCAGTFEGADTSTARFTPTALPTATCNNCQVSVAVSDGRGGQTTGTVTLCISKDVAKHLPPTIVRSYQSTLTANPGQQVTFEVVASDPENSSINFTWSASTGSLGVAETTTSTSRLTWAAPACINPGTTPSIVATATNSFSLSVSRTFAVSNLPTCLPSANTWTHTTPMLSRRRNHYATLLPSGKVLFVGGYTRPDDSSSVDNTAPSELYDPVTGTWTALTSRAKAGDGFAAVTLPSKKILIVGGFPILGSPLSTAELYDPDSDSYSSITMSSTRLYPTATLLQSGKVLVAGGDWYYGGHKIPEVYDPITGTWTPTGPMSSARTHPSAVLLKSGKVLISGGENSDGEKLSTAEIYNPAEGTWTLAAPMLSAHVGHTLTLLPSGKVLLVGTVSNGTGGAELYDPETNIWTNADSGIIGFGYHTSTLLPSGRVLAIGGSNSAGIYNPLTNSWMPTGPEVTHTRYLHSATLLPSGQVLVAGGGDSSMYAHPVITADIYTP
>NZ_CP022098.1|WP_157758912.1|9639258_9639552_+|hypothetical-protein
MPHAFGDDERVAAKGDGDVVVPTREAAALVVVEPELSLQILVDTLGSPALHDEANELLLCHAARHGDKEVVGWIGLFLAPLDEQPEGFLLPLEHRSG
>NZ_CP022098.1|WP_095989801.1|9641102_9641756_-|glycosyltransferase-family-2-protein
MIGVVIPAHNEESLLEECLASVVRASIHPALLGEDVRSVVVLDDCTDGSARVARRWGVNTLCVEARNVGQARALGCRVLRAQGARWLANTDADSRVFPDWLAVQLALDVDVVCGVVEVGDWSPHSARARRRYESAYQDIDGHSHIHGANLGVRTRAYVGAGGFPPLSAHEDVALVDSLRRSGARIAWSARARVLTSARRDARARGGFGDYLNGLEVD
>NZ_CP022098.1|WP_095989802.1|9641752_9642352_-|methyltransferase-domain-containing-protein
MSVPMAHFERMYADSEDPWEYRRRWYERRKRALTLAMLPHARYARAFEPGCSIGELSAELAARCDALLVGDGSEAAVRVARRRLAPWPHVRVEQRLLPDSWPEGTFELVVLGEFGYYLDAKALLGVRERAVRSLAPEGVLVACHWRPPIAEAPLTGDEVHEVLGRARGLHRLARHEEEDFLLEMWSPGADSVARREHLR
>NZ_CP022098.1|WP_095992495.1|9642348_9643029_-|PIG-L-family-deacetylase
MPSLEPALLVPEGRRAVIVAPHPDDEVLGTGGLLARLGRLGRDVLVLAVTDGTASHPGSTSWPVERLARTRPRETQEALQRLGLGGARVERVGIPDGAVTENEERLVEWLGARLRPDDVVLATWRLDGHPDHEAVGRAASRACAALDGRCVEFPIWMWHWARPGDTRVPWSRARRIELDEATLALKRRAMEAYVSQLEPDSTTGNPPIVPPYALERLMRPFEVVFT
>NZ_CP022098.1|WP_071905527.1|9643097_9644165_-|acyl-CoA/acyl-ACP-dehydrogenase
MYSSGLREQSAHQEEHFSIEALQLLLGRLEGPAEEPVGLAPARGLQQLLSGGFGALPLPGRGQTLLRWRALAAVAAVDLGLIKLFEGHTDALAILAELGAEPPPAGSSWGVWASEPPQARVRVSGRADGRVELSGRKAWCSGAPQVSHALVTAWDAEERQCLVAVAMKQAGVRVTKEGWHAVGMASSASVDVLFEGAVGTRVGPPGGYTARPGFWQGGAGIAACWYGAAAAVGETLRAHCARREEPHARAHLGAVDTALGGARALLREAAAWIDAHPREDASLVAWRARAGVEAAAELVLRHTGRAVGAGPYCRDARVARRMADLPVFLRQSHAERDLEALAGLVVKEGAGGWSL
>NZ_CP022098.1|WP_157758913.1|9645609_9646005_-|glycosyltransferase-family-2-protein
MNDRSTDATGSLADRFAQEEPRLQVVHIEQLPADWLGKVHAMQRGLERASGEWILFSDADVHLAPKALERIVAYAEHEGLERIGRREAVLRGRAGAEGPRRAADGCRPSCEPGRCRGQAASLGMPAQAALP

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_20

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_20

10034991-10035094

Orphan

Consensus_repeat	Method
CACGGCGGGCTTGGCGGCGGGCG	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP022098_20

>merge|NZ_CP022098|20|10034991-10035094|CRISPRCasFinder
GGGCGCGGGCCTGGCGGCCGGCGGAGGAGACTTGGCGGCCACGGCGGGCTTGGCGGCGGGCGCGGCGGGCTTCGCGGTGGGAGCAGCGGGCCTGGCGGCGGGCG

>NZ_CP022098|20|18|10034991-10035094|CRISPRCasFinder
GGGCGCGGGCCTGGCGGCCGGCG	GAGGAGACTTGGCGGC
CACGGCGGGCTTGGCGGCGGGCG	CGGCGGGCTTCGCGGTGGG
AGCAGCGGGCCTGGCGGCGGGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_095990089.1\|10033118_10034048_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|132060
NZ_CP022098.1\|WP_095990081.1\|10017112_10018297_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	unknown	unknown	gnl\|CDD\|223594
NZ_CP022098.1\|WP_095990087.1\|10026124_10029106_-\|BamA/TamA-family-outer-membrane-protein	unknown	unknown	gnl\|CDD\|227116
NZ_CP022098.1\|WP_095990092.1\|10039353_10039935_-\|elongation-factor-P	unknown	unknown	gnl\|CDD\|234788
NZ_CP022098.1\|WP_095990086.1\|10022448_10024704_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095990096.1\|10044591_10045164_-\|type-4a-pilus-biogenesis-protein-PilO	unknown	unknown	gnl\|CDD\|309474
NZ_CP022098.1\|WP_095990083.1\|10019234_10020479_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340886
NZ_CP022098.1\|WP_071903507.1\|10040043_10040406_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224929
NZ_CP022098.1\|WP_095990091.1\|10037311_10038697_-\|acetyl-CoA-carboxylase-biotin-carboxylase-subunit	unknown	unknown	gnl\|CDD\|236307
NZ_CP022098.1\|WP_095990097.1\|10045178_10045859_-\|pilus-assembly-protein-PilN	unknown	unknown	gnl\|CDD\|225707
NZ_CP022098.1\|WP_095990094.1\|10041144_10043874_-\|type-IV-pilus-secretin-PilQ	unknown	unknown	gnl\|CDD\|274173
NZ_CP022098.1\|WP_095990082.1\|10018311_10019238_+\|Ppx/GppA-family-phosphatase	unknown	unknown	gnl\|CDD\|223326
NZ_CP022098.1\|WP_157758942.1\|10040440_10041106_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095990095.1\|10043942_10044515_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377322
NZ_CP022098.1\|WP_095990084.1\|10020520_10021594_+\|NADH:flavin-oxidoreductase/NADH-oxidase	unknown	unknown	gnl\|CDD\|239242
NZ_CP022098.1\|WP_157758941.1\|10021606_10022371_-\|arylamine-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366312
NZ_CP022098.1\|WP_095990098.1\|10047268_10048294_-\|prepilin-peptidase	unknown	unknown	gnl\|CDD\|377700
NZ_CP022098.1\|WP_002631849.1\|10045889_10046972_-\|type-IV-pilus-assembly-protein-PilM	unknown	unknown	gnl\|CDD\|378558
NZ_CP022098.1\|WP_095992519.1\|10024711_10026049_-\|acyltransferase	unknown	unknown	gnl\|CDD\|153254
NZ_CP022098.1\|WP_095990088.1\|10029171_10033113_-\|translocation/assembly-module-TamB	unknown	unknown	gnl\|CDD\|367909

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095990089.1\|10033118_10034048_-\|AAA-family-ATPase	gnl\|CDD\|132060	TIGR03015, pepcterm_ATPase, putative secretion ATPase, PEP-CTERM locus subfamily. Members of this protein are marked as probable ATPases by the nucleotide binding P-loop motif GXXGXGKTT, a motif DEAQ similar to the DEAD/H box of helicases, and extensive homology to ATPases of MSHA-type pilus systems and to GspA proteins associated with type II protein secretion systems. [Protein fate, Protein and peptide secretion and trafficking].	2.62122e-54
NZ_CP022098.1\|WP_095990081.1\|10017112_10018297_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	gnl\|CDD\|223594	COG0520, csdA, Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones].	1.43226e-57
NZ_CP022098.1\|WP_095990087.1\|10026124_10029106_-\|BamA/TamA-family-outer-membrane-protein	gnl\|CDD\|227116	COG4775, COG4775, Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane].	1.5311e-60
NZ_CP022098.1\|WP_095990092.1\|10039353_10039935_-\|elongation-factor-P	gnl\|CDD\|234788	PRK00529, PRK00529, elongation factor P; Validated.	2.56988e-101
NZ_CP022098.1\|WP_095990083.1\|10019234_10020479_+\|MFS-transporter	gnl\|CDD\|340886	cd17328, MFS_spinster_like, Protein spinster and spinster homologs of the Major Facilitator Superfamily of transporters. The protein spinster family includes Drosophila protein spinster, its vertebrate homologs, and similar proteins. Humans contain three homologs called protein spinster homologs 1 (SPNS1), 2 (SPNS2), and 3 (SPNS3). Protein spinster and its homologs may be sphingolipid transporters that play central roles in endosomes and/or lysosomes storage. SPNS2 is also called sphingosine 1-phosphate (S1P) transporter and is required for migration of myocardial precursors. S1P is a secreted lipid mediator that plays critical roles in cardiovascular, immunological, and neural development and function. The spinster-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.96353e-113
NZ_CP022098.1\|WP_071903507.1\|10040043_10040406_-\|hypothetical-protein	gnl\|CDD\|224929	COG2018, COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid [General function prediction only].	6.45264e-05
NZ_CP022098.1\|WP_095990091.1\|10037311_10038697_-\|acetyl-CoA-carboxylase-biotin-carboxylase-subunit	gnl\|CDD\|236307	PRK08591, PRK08591, acetyl-CoA carboxylase biotin carboxylase subunit; Validated.	0
NZ_CP022098.1\|WP_095990097.1\|10045178_10045859_-\|pilus-assembly-protein-PilN	gnl\|CDD\|225707	COG3166, PilN, Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion].	1.22209e-11
NZ_CP022098.1\|WP_095990094.1\|10041144_10043874_-\|type-IV-pilus-secretin-PilQ	gnl\|CDD\|274173	TIGR02515, Putative_DNA_transport_protein_HofQ, type IV pilus secretin (or competence protein) PilQ. A number of proteins homologous to PilQ are involved in type IV pilus formation, competence for transformation, type III secretion, and type II secretion (also called the main terminal branch of the general secretion pathway). Members of this family include PilQ itself, which is a component of the type IV pilus structure, from a number of species. In Haemophilus influenzae, the member of this family is associated with competence for transformation with exogenous DNA rather than with formation of a type IV pilus; the surface structure required for competence may be considered an unusual, incomplete type IV pilus structure. [Cell envelope, Surface structures].	6.83635e-173
NZ_CP022098.1\|WP_095990082.1\|10018311_10019238_+\|Ppx/GppA-family-phosphatase	gnl\|CDD\|223326	COG0248, GppA, Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism].	4.82585e-86
NZ_CP022098.1\|WP_095990096.1\|10044591_10045164_-\|type-4a-pilus-biogenesis-protein-PilO	gnl\|CDD\|309474	pfam04350, PilO, Pilus assembly protein, PilO. PilO proteins are involved in the assembly of pilin. However, the precise function of this family of proteins is not known.	5.56324e-49
NZ_CP022098.1\|WP_095990095.1\|10043942_10044515_-\|hypothetical-protein	gnl\|CDD\|377322	pfam04351, PilP, Pilus assembly protein, PilP. The PilP family are periplasmic proteins involved in the biogenesis of type IV pili.	6.64056e-13
NZ_CP022098.1\|WP_095990084.1\|10020520_10021594_+\|NADH:flavin-oxidoreductase/NADH-oxidase	gnl\|CDD\|239242	cd02932, OYE_YqiM_FMN, Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis. Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing agent. The YqjM enzyme exists as a homotetramer that is assembled as a dimer of catalytically dependent dimers, while other OYE members exist only as monomers or dimers. Moreover, the protein displays a shared active site architecture where an arginine finger at the COOH terminus of one monomer extends into the active site of the adjacent monomer and is directly involved in substrate recognition. Another remarkable difference in the binding of the ligand in YqjM is represented by the contribution of the NH2-terminal tyrosine instead of a COOH-terminal tyrosine in OYE and its homologs.	0
NZ_CP022098.1\|WP_157758941.1\|10021606_10022371_-\|arylamine-N-acetyltransferase	gnl\|CDD\|366312	pfam00797, Acetyltransf_2, N-acetyltransferase. Arylamine N-acetyltransferase (NAT) is a cytosolic enzyme of approximately 30kDa. It facilitates the transfer of an acetyl group from Acetyl Coenzyme A on to a wide range of arylamine, N-hydroxyarylamines and hydrazines. Acetylation of these compounds generally results in inactivation. NAT is found in many species from Mycobacteria (M. tuberculosis, M. smegmatis etc) to man. It was the first enzyme to be observed to have polymorphic activity amongst human individuals. NAT is responsible for the inactivation of Isoniazid (a drug used to treat Tuberculosis) in humans. The NAT protein has also been shown to be involved in the breakdown of folic acid.	9.16135e-65
NZ_CP022098.1\|WP_095990098.1\|10047268_10048294_-\|prepilin-peptidase	gnl\|CDD\|377700	pfam06750, DiS_P_DiS, Bacterial Peptidase A24 N-terminal domain. This family is found at the N-terminus of the pre-pilin peptidases (pfam01478). It's function has not been specifically determined; however some of the family have been characterized as bifunctional, and this domain may contain the N-methylation activity (EC:2.1.1.-). It consists of an intracellular region between a pair of transmembrane. This region contains an invariant proline and two almost fully conserved disulphide bridges - hence the name DiS-P-DiS. The cysteines have been shown to be essential to the overall function of the enzyme in, but their role was incorrectly ascribed.	1.12858e-50
NZ_CP022098.1\|WP_002631849.1\|10045889_10046972_-\|type-IV-pilus-assembly-protein-PilM	gnl\|CDD\|378558	pfam11104, PilM_2, Type IV pilus assembly protein PilM;. The type IV pilus assembly protein PilM is required for competency and pilus biogenesis. It binds to PilN and ATP.	2.22939e-81
NZ_CP022098.1\|WP_095992519.1\|10024711_10026049_-\|acyltransferase	gnl\|CDD\|153254	cd07992, LPLAT_AAK14816-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized glycerol-3-phosphate acyltransferases such as the Plasmodium falciparum locus AAK14816 putative acyltransferase, and similar proteins.	9.10332e-59
NZ_CP022098.1\|WP_095990088.1\|10029171_10033113_-\|translocation/assembly-module-TamB	gnl\|CDD\|367909	pfam04357, TamB, TamB, inner membrane protein subunit of TAM complex. TamB is an integral inner membrane protein that forms a complex - the translocation and assembly module or TAM - with the outer membrane protein, TamA. TAM is responsible for the efficient secretion of the adhesin protein Ag43 in E.coli K-12.	1.01172e-38

>NZ_CP022098.1|WP_095990089.1|10033118_10034048_-|AAA-family-ATPase
MTTYLDYFELTQEAFSNAPVSRFYYNSAQHSQALTRLMHAVSYMKGLSILVGDIGAGKTTLARRMLDSLPESEYEAALLVIIHSGITANWLLRRIALQLGVENPAQEKLALLSQLYQRLLQIYESGKKAVVLIDEAQMLETRELMEEFRGLLNLEVPERKLISFVFFGLPEIEKNLKLDPPLAQRVALRYKLEPFTAESTEAYIKHRLRLAGCPRMPFTAEALATVHQRSGGTPRVINSICDNALFEAFLLREQTIGQPLIQRVADNLGLQGGSAATTPPLSTPASRPVSSPKVDLAEIDRYLEGLGKL
>NZ_CP022098.1|WP_095990088.1|10029171_10033113_-|translocation/assembly-module-TamB
MAPRNRQQGARRIPAWLIVLALVVGTVLLLRTRTAWDTVCAQARRQLPALLGLDVGIGECEVDPLGQRLVLRGVSVSEPGKSDPPLFAADQAEVQLGLPNLFSGQFAIDLVRVSRPRLALDLTRPRAPRSEPGVCPLVPLRRLSLARLSLTGAEVRLLLPGGRQVELSELDVNLRERWGEEEFEVEARRGLVRLGPGQELALGRLAVSGALDVEEQLLEVDRGEVALDEATVNISGRVERLCEPNLALDAQLFLPLRTLSRSGLLPRPAQGHLWTRLTVNGPPAAPTVSAELSGSGLAYGKYSPGTFTARLIYSGETVTLEELRLPIGAGDARITGSLALRSGLPVSLVLDVHDASFGRILEKAGVPGSWVDFPITTAKARLSGTLLPRLQLSGDLDLSHGRFMLASRAFDAPADRGRTFLTYAQGHARTRVSLLSDRVTFSDMQIDSGRSRLGGGATLFFDTQRGLLVDVRGDVDLSDFGHIAQLAWAGRGSVSTTVEGPYTKVRIGADLSLRDFEFWNFDLGVVQGKVTYQDKVLGLPMFSGQKGRTQYFGNAALTFGRSLHLRTEVEVPRGRTEDLIDFIAPMHPNVSLLQGPLVGEASGRVEIDSPLEQFEGLVALDFRNTTYYGRHMGDGSTRLRFDRSGAMVLERTALEGALGLTWVEGSFFLSGPDKGRLDYRFGGERLSLAELVGPESARRLGVEGMLALEGTVSGDTDVPVTMARVWGPRVTFAERDLGNMDLEARLEGRELQVVGRPSRDTSGVLSLRLKEPYPFEALVTLELPEIRPLLPANAFTQGVSGSIKAVVQAQGALRDTDALLLKAKVERLALSREDISAENEGPIVLDYANGRLVVPSFTLRGQDTTLSASGWATPEQMEFFLQGAMDLRLLESLAPMFTRTAGRVEFSAVASGRPDRPSLEGSALISDARLSLRDQPMAARSVSGLVQFTEQRILLDELKGTLNEGQVKAKGQVRLDDFQPKEVLLDVHLTEVSMRFHEDLPFTTTGELSLTGTPEALRLGGVLDILGLRYRRGLELEDILKRLSRRIVLPSPTTERPREYLTLDVRLNLRDVYVDNNLARARLFGSLDLTGTNARPGVLGTVETDADSQAFFRNNQFTITRGQIEFQDRYGIDPVFDLRAQSQVREYQVKLHAFGRPAAPQVLLTSEPALPEGDVLSLLTLGFMSTDRETATSAGVGLAAEAFFNMSGLDRQVKRFLPSNPVIKDLSLQISTTYNDVTQQAEPTARLESKFLTEQLKIGLSQPVSGRGTRARAEYRFDNRLSAQLQWDNEHSENALSPLGNLGLELKLGWESE
>NZ_CP022098.1|WP_095990087.1|10026124_10029106_-|BamA/TamA-family-outer-membrane-protein
MSVELHLPGNADTQGLSTLVAVRKGQALSARAVRRSVERLWASERFSDIVVRSVDVPGGVRVVFELTPVQPLLRLSVEGNVVLSDEALLDVLEARGIVVGQRLDEERLEAALEGMARAYGRQGYNEARIELTREQETGGVALVFTVFEGRPTQVAAVSVTGSPGLPLSELLATLGLRVGGVLDRGGLDAGLERLRTLLRERGHWRASVGRPILDEAAGAATVVVPLSAGPRFSLHFHGNHHFADALLRRVLAYEGAEPLDSATVARLARRLELFYLYRGFHSVHVEPRELVHPQGEAAVLAFDIEEGPVLRVSRVHFRGNTVLSSEALREILTERLRASTPQPGTPPRLRGVAEMGPEGSRRGPGEWLLDPAIVFVEEAYRDAAEAMTEAYRERGFLEAHVRFTRMRESLTRGLAEAWFEVHEGTPLRVAAVRLEGGPPGFEGQRFVHVAPGEALNPDTVESGRRELVTELGRQGYLFARVEAEPTPGAEGVSLLFRMEPGPRVTVGRILVRGLVRTEEDVVRATVRLKEDEVVVPDKLVESQRRLALLNIFRQVTVRLDKPEVPEASKDIVVEVRERPRWEGEIAGGYFLSEGPRLVLDAARTNVDGRGLNLSARLKLNYVGWSTQGVEKANALRVTCEKVPEECPAPAPWMNDFGGRAVLSAVLPRLYGLQPLEVGARLDLITERVQRPSYLSSRVAAVTGLDWSVTRWLNATLQYELEGNVLQAGARPLATLNRADQERLRFPYGFFILHSLRASAAVDLRDNPANPHKGLLVSTSAEWMRDLQSYETTSSGTPLEALPLHNAKLSGNASVYAPLPSGTVLAVSVRAGIILPLEKDARVIGSKRFFLGGSSNLRGFREDGILGEDRRTQLRSQVADCRSLIQPAGCSAELLTLLAGQPPVSEGGELFTLAKTELRIPVRSSFDLGLFLEAGNLWLDWTAYRFSTLRYTVGAGFRYVTPVGPLAFDVGINLDPDEVLNEPWGQIHFSIGAF
>NZ_CP022098.1|WP_095992519.1|10024711_10026049_-|acyltransferase
MFYSFVRTVVALLLRLFYRVKVHAPQAETEGPVIFVGNHPNGLIDPALVFILTRRQVTFLAKEPLFRIPVIGALLRGLGALPVYRKQDDPTQMGRNEGTLDAARGALVAGRAITLFPEGKSHSEPGLAELKTGAARIALGAAKQGAAVRIVPVGLTYADKHLFRSEVLIEVGTPIDVRDFLPADGADEAASVRALTERIAGALRAVTLNLDKWEDLPLIQLAEDLYALRQKQAKDPERLRYWARGLELFRAEEPERFERVRGQMMTFQRHLSLVRADPADLSLEYQPGPVARFALKNLLLLVVGLPLSLVGLCLFYVPYLFPRWASRNAELDVQATVKFLAAAVTSAVWWAALTVGAWLWLGAPVGVAVLLGVPPLALLTLYFSERWGVVRHDVSVFFTLGNRARLKARLLAEGGGLAEQVERLAGEYHPRLASAAATPDVIPGR
>NZ_CP022098.1|WP_095990086.1|10022448_10024704_-|hypothetical-protein
MSSVDPHWPDSLQALYEQASGAPADAVLASRPQWAEQLADWVRRATLEERERAQAATWARLDVGPRSPGELLFLLVHSGELLWPYSEAPRELLQRLLSRQDQLVQALRGGGQGEAVEPLTREMDAELSKVVARYLKRHPDELRRLVSGVRCTFDGRVLCFNDTVAVDLKTLLGSDKRLIGRLDQLRELLPHLREGRDKLVAFIRERAAKIPWRECRDILEEKLFQLVASARGPGELRGFLGCYAHGKREARWCTRAGLLLARNLEEGGAVAVIDNLSEVLVSFEPPVEGLRASLNAVVASLHEDREFARHRRVVDTCWERLVPKAEPGLALVLLWVEERLFRVALRQGAEDAFECRNRARERVRSLPVADALEWLAEECAELWPRMESEHRPGADELAAWRQEVTRRYAKKPVLRKAAMEFVLWCAPDAAASEAELVTLSLVKTSTDRRLLRRLGDHPSTRVRFRVRAINAWLAAGPESSEPETPATLTGALRHLRSAGALTLGGGRTWLRDRDLEELLLGAFGRVERDFSARYPEHFREDESVLVSRLLEDLKNEVDSIRSDLSILLAQGQPVPLELGFQYRRREDAGQGTEVVEGTRPAGVELGFVLTVEVEGFLTTKRAVLVQARKLEQRGEGQWAPNLRLAREQVDAVLGRSESSVCLFLVPPALRAECWMIPARLVRGLMDAQGSLSTVSREGAQRVARSLAQWMTYELLGLWAGDDRPGVLEWAEGRAQGGPDFIVELSVRKNGR
>NZ_CP022098.1|WP_157758941.1|10021606_10022371_-|arylamine-N-acetyltransferase
MDLGHYLQRMGYRGPLRPTLETLRRLHLQHLEALPFENLDVLGGRPMVLEEEALFDKLVRGNRGGLGFELNGLFAALLRELGFQVTYLAARVSASGEWPMAPGFAHLVLEVTLEEKWLVDVGFGEAFDEPLPLVPGRWPTAGRMFLLEPQGEEWVLAREEPDGSCPWLYTFSREPRRWEDVVALGRDYPPPGSPLRRELLCTRKTPRGRVTLRGERLILSEGGHCVERWLGAAEEREHLLLSHFGLRPGSLGSR
>NZ_CP022098.1|WP_095990084.1|10020520_10021594_+|NADH:flavin-oxidoreductase/NADH-oxidase
MSSLLFSPLRLRGVTLKNRIVVSPMCQYSSEDGFANDWHFVHLGSRAVGGAGLIILEASAVEAIGRISPQDLGIYKDEHVEPLARIVKFLHEQGSVAGIQLAHAGRKASSSPPWMGGAPIASTAQGGWTPVSASGLPFDPRNPVVPTALDETGIQRIIRSFAEATDRARAAGFRVVEIHGAHGYLLHEFFSPLSNQRTDRYGGSFENRTRLIREVTRAVRQRWPEELPIFVRLSATDWVEEGWSVEDSVALAKLLKEDGADLIDCSSGGAVPGVRIPAGPGYQVPLSERVRREADIATGAVGFIQSAFQAESTLRTGQADVVLLARELLRDPYWPLHAAKELYTQVAWPKQYERAQN
>NZ_CP022098.1|WP_095990083.1|10019234_10020479_+|MFS-transporter
MSPPVAVASPAAAPNSTYALFILSLINLVNYLDRYIVTVALPHIQRDFQLDNTQAGLLGSFFMVVFMLASPISGFLGDRVPRRFLVAGGVLLWSLATGASGLASTFAALMVARACVGIGEAGYGAVAPSIISDLFPREQRTRVLSVFYIAIPVGAAAGYGLGGWLSNAYSWHVAFYAGGVPGIILAVMAFFMPEPQRGAMDGPDAQKKLPFLVGLKGLGRNPAFWWTTSGYTLMTFSIGGLAFWLPSFLVNERGMALDRAGFLSGAVTALAGLTGTMAGGWLGDRMDQRMPGGGLRLSGVGLLLAAPLMVLAVKVSAHAPMFAIIFMAQFLIFLNSGPINAAIVNGVPPAFRAFAMGLNVLFIHMLGDALSPTVIGKLADVSSLAVAIQVNAIPVLLGGLALLMAGKAFRHVND
>NZ_CP022098.1|WP_095990082.1|10018311_10019238_+|Ppx/GppA-family-phosphatase
MPRYATIDVGTNSVLLLVADRHPDGRFHAVQERAEITRLGRGVDQSRRLSPEGMETTLQVLTDFADEARRLGAEAIAVSATSAARDAENGAEFLAAARTRAGVTVEIIPGELEAQLSFTAAYADFGRTARGPLVVVDIGGGSTEFIYGDTAGKVTFRHSFDVGSVRMTERYVRADPPSAEDRTRVEAHLRETFSSLPPCPPGAQLVGIAGTVTTLFTVRHAIDPYDARRVHGGTLSLAELDALVDCLCQKPLAERQKLPGLQPKRADVIPAGALILRECLRALRLDNCLVSDRGLRWGLLAHRFGATS
>NZ_CP022098.1|WP_095990081.1|10017112_10018297_+|aminotransferase-class-V-fold-PLP-dependent-enzyme
MDRSPLRAHWALDPETLFLNHGSFGACPTRVLEEQSRLRARMEANPVRFLHRDLPDLADAARGALADFLDANPDELAFVPNATTGVNTVLRSLRFAPGDELLTTDHEYNASRNALDFVAQHWGVQVVVAKLPWPTPSPQAVVDAVLARVTERTRLLLIDHITSQTGMILPVASLVRTLRSRGVETLVDGAHGPGQIPLSLRELGAAYYTGNCHKWLCAPKGAAFLHVRRDAQALIRPLVISHGYNSRREDRSRFRLDFDWLGTNDPTPFLCIPKAIEVMAGLVPGGWPEVMARNRALALSARTLLHQRLGGAPRCPEDMVGSMATVALPDGFPEEPSVLGLDPLQERLFLEHRIEVPITPWPRAPQRHVRVSAQLYNSLAEYQRLAEALEALPR
>NZ_CP022098.1|WP_095990091.1|10037311_10038697_-|acetyl-CoA-carboxylase-biotin-carboxylase-subunit
MFKKVLIANRGEIALRVIRACRELGIATVAVHSTADANALHVRFADESVCIGPPASKESYLNIPQLLSAAEITRADAIHPGYGFLSENAEFAKVCQDCKIHFIGPRPEMIRLMGNKVRARQAAREANLPLLPGSPTALKDAREAEVFAREIGFPVILKAAAGGGGKGMKIVREPGALPQAFATAAAEAVASFGNGDLYIERYVERPRHIEIQIVADEHGRVIHLGERECSVQRRHQKLIEESPSVALTPELRQQMGEVSVRAMEKLGYNNVGTIEYLLDENGRFYFMEMNTRIQVEHPVTELVTGIDLVREQIKLSSGQPLQRKQEDIQMRGHAIECRVNAEDPVTFAPWPGKITAYSAPGGYGVRVDSSAYENYTVLPYYDSLLAKLIVFAEDRPTAIRRMQRALGEYVVQGIRTNIPFHRAALAEESFIEGNYDTRFVERLLASETGTKRLRKAIEETP
>NZ_CP022098.1|WP_095990092.1|10039353_10039935_-|elongation-factor-P
MAGVIDTSEFRNGLKIEIDGEPFVIEYFQHVKPGKGSAFVRTKIRSLLSGRVLEPTMKSGDKVGVPDIEEKAMQFLYVQDGDYYFMDKRNFEQTFLSEKVLGDAKNFLKENIDADVLFWNGKAIAVTLPNSVDLKVTKCDPGVRGDTVSGALKPATLETGFVVNVPLFINEGDVLKIDTREGGKYLTRVATAG
>NZ_CP022098.1|WP_071903507.1|10040043_10040406_-|hypothetical-protein
MSFRTHLESVVNQVDGALACSVMGFDGIAVDTHQNEEALELELNGAWIEYANLLGQLRQAAEALKTGEVQEVSINSERVLTLMRLVSPEYFLVLALRADGNYGKGRYVLRLTAPKIRAEL
>NZ_CP022098.1|WP_157758942.1|10040440_10041106_-|hypothetical-protein
MKRLMMVAALAVAQSGCASSQEDAPVLFSNVLALAGSPGGACEPDTSKFISQGSLDVAGGDNYVMAVRVRSTIPAARTILVGDTPTLVGGESITLTEFVYRYESSPELGLPDEDRAATNAVIPAGTTGDSSYVPVNAFGPLALEKLLTATPGEPGVSVIVYIKARGRVGSTSNAESNEFSFPVRVFRSLDCSSNPVTAGICSFGQDVRTACPPPTFAPTTP
>NZ_CP022098.1|WP_095990094.1|10041144_10043874_-|type-IV-pilus-secretin-PilQ
MLEESVVTRGKLVSVVVALVVATLGLDSQAAELNTLRDLKVVQTGAGAQVVVTGTRAPTFTVFRLSGPERLVVDLSSADATGIKGHHNGQGPVVGVVASQFSDERASVGRLLVALQQAAQYDVRADGNRVVISVEGTQAPAPVAAAPEVKTPAPEVKTPAPEVKPEPAPVASAGPAETRAASPRPVAEVSQDKAAALPENVVAAEADEREVAHPARRITGLSFARDTLNIRADGEVARYEVLELADPPRLAVDVYGVGLAARAPRVNSGAVKDLRVGAHSDKVRLVLDVRNTMPAYHVERSGRGLAVVFGGKLARQSNAPASTPEKMVAESEPLRTTPVDARLPAVDVKELSFDENESGGRVNLKLSGAVAWKVERPDPRSAVLTLENARLPRRLERSLDTSELDTPVKMISAFSVPGEGNRVRLVVAADGAIEENVSQVSGGLSWRLSVNGVKTEQVTVTQRTAGFTAEAPTYAAEGAPQQARYRGKKVSFEFKDIDIQNLLRIIAELAKKNIVVSDDVTGKLSLRLRNVPWDQALDIVLRTKSLGKEDLGNILRVAPLKTLEEESKLRQERKKSLIALEDLVVNLIPVNYATASEMAARVKDVLSERGTVTVDTRTNVLITKDVRANIEKARALVRNLDTQTPQVLIESRIVEANTTFSRELGVQWGGQAIASRSVGNATGLIFPSTAVATGGVTGTAPGLPPIPNFAVNLPAAADVGTGGAMSFVFGSAGGALALNLRLSAAELEGTLKTISSPKVTTLDNNTARISQGVSLPFSQVSSAGANTTFVEARLSLEVTPHITQDGSILMTINAQNNQPDPANTGSNGQPAIQRKEANTQVLVKDGDTTVIGGIYVRRGSTTTASVPFLSKIPILGLLFKRHAESDNRQELLIFITPRILNRQTIAQSL
>NZ_CP022098.1|WP_095990095.1|10043942_10044515_-|hypothetical-protein
MKTFHSMFISGALALSLVGCGEEEPPPPPVAARPAAQEEPAPEKPAEPAVAAPLYVYNYNPVGKRDPFRSPVEDIKAADTPVGAQLLTACTEALCQWDIDQLKLVAVVSGDANPMAMVEDPMGRGHIVRRNSRVGRSGGKVTQILRDEVVVTETITTPERVVYNPVKLGLKQDDKMDPAYNMMTGKNWEP
>NZ_CP022098.1|WP_095990096.1|10044591_10045164_-|type-4a-pilus-biogenesis-protein-PilO
MDKYLDRIVKAPPAAKFGGLAALVVLMTAANYFLVIEPLENESVSLRAQQRKLDLDLAEKSEIAQNLNERRREMDVLEQKLAEALTELPQNKDVEELLAQLNDIGKKSGLEISRVEPGPESVVGDEFFSRIPVRMVVSGNYHEIAMFLQEVSNMRRIVNVNNIKLEGARVKNEKVVLSSSFMATTFRFVK
>NZ_CP022098.1|WP_095990097.1|10045178_10045859_-|pilus-assembly-protein-PilN
MMIRINLLPVRKKVKQEAGRQILALFALVLLGAGAGNFFWYSDREGVVVKQREGLAQTRKRIADLEKTIGEVQHINARKAEVEKKLAVLDELRRGRSGPVRMLDALANSIPKKAWIKSFNEERGAVSLLGSAVSHDDVAELMRNLNGMVWTPKGIGRLVEQRRDAKTSRVELLSAEVSIEEFPVGDIKPFFTNVDLRSTQQQNQNSKPGDVSTVEFDISLSSNYAI
>NZ_CP022098.1|WP_002631849.1|10045889_10046972_-|type-IV-pilus-assembly-protein-PilM
MAKGKLALGLDIGSTSVKMILLKEQRKRGQVSYALQSFGMKPLPPEAIVDGALMNSTAIVQALQELLTELKIKSKDVAIGVSGHSVIIKKIQMPRMSQEELEESIQWEAEQYIPFDVKDVNIDTQILDAGGNDATGQMDVLLVAAKKDMINDYTTVVSESGLLPVVVDVDAFAVQNMFAANYDIPDKETVVLINAGASVVNINIISNGITVFTRDVTIGGNQFTEEIQKQLNVSYEEAETLKIGGTRSDADAVVPQEVERVLLSVAEQVAGEIQRSLDFYAGTAVDANFTKVYLSGGTAKIPALFKTIETRVGVPVEILNPFRKIDVDNRKFDPAFIMEVAPMAAVAVGLALRRPGDKLA
>NZ_CP022098.1|WP_095990098.1|10047268_10048294_-|prepilin-peptidase
MAVAWVVVLGLVFGSFLNVVIARVPTGESIVRPRSRCPKCGHTLAWFDNVPVLSWLVLRGRCRSCGQPISWRYPLIELLTGALFFACQRRFGWTPELVSALVLVLVLVPLSFIDLEHWILPHELTWPGIAAGVVLSAPMGLVRLRDSILGALVGFFVFWAMEWLGEKIFKKEALGAGDKDLLALIGAFLTWKPLLGIIFLSSLQGAVVGSVMLLLHGRAGPAPAPDESPPTPASPDTDAPSPEASDAASAPPPEGEAHPEGAMAQPARGAEGVVEGEKGEEGEKGEEGEMGEDEEDDWVPGPTNLPFGPWLSIAALEVMLLGPWLSAILPVPMNVLVTGVR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_21

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_21

11351668-11351777

Orphan

Consensus_repeat	Method
GCAATCCTTGACGCCTTGCGTTGAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP022098_21

>merge|NZ_CP022098|21|11351668-11351777|CRISPRCasFinder
GCAATCCTTGACGCCTTGCGTTGAAATGAAGATGACAACGTTACGACGCGCCCGGCCATCCGGCGGACAGGGGAGAGACCGGCGGCAATCCTTGACGCCTTGCGTTGAAA

>NZ_CP022098|21|19|11351668-11351777|CRISPRCasFinder
GCAATCCTTGACGCCTTGCGTTGAAA	TGAAGATGACAACGTTACGACGCGCCCGGCCATCCGGCGGACAGGGGAGAGACCGGCG
GCAATCCTTGACGCCTTGCGTTGAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_095990984.1\|11339177_11340389_-\|methionine-adenosyltransferase	unknown	unknown	gnl\|CDD\|235374
NZ_CP022098.1\|WP_095990994.1\|11356340_11357576_+\|chitosanase	unknown	unknown	gnl\|CDD\|366548
NZ_CP022098.1\|WP_095990985.1\|11340620_11341199_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|377516
NZ_CP022098.1\|WP_095991000.1\|11365334_11368553_+\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NZ_CP022098.1\|WP_095990990.1\|11347191_11347965_-\|urease-subunit-gamma	unknown	unknown	gnl\|CDD\|215172
NZ_CP022098.1\|WP_095990998.1\|11362172_11363279_-\|mandelate-racemase	unknown	unknown	gnl\|CDD\|239444
NZ_CP022098.1\|WP_095990989.1\|11345479_11347195_-\|urease-subunit-alpha	unknown	unknown	gnl\|CDD\|237305
NZ_CP022098.1\|WP_095990986.1\|11341344_11344002_+\|MMPL-family-transporter	unknown	unknown	gnl\|CDD\|223964
NZ_CP022098.1\|WP_157759042.1\|11359198_11360677_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371915
NZ_CP022098.1\|WP_095990991.1\|11348968_11350600_-\|cell-division-protein-FtsK	unknown	unknown	gnl\|CDD\|379799
NZ_CP022098.1\|WP_157759041.1\|11338588_11339107_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237865
NZ_CP022098.1\|WP_095992625.1\|11348059_11348902_-\|urease-accessory-protein-UreD	unknown	unknown	gnl\|CDD\|376611
NZ_CP022098.1\|WP_095990993.1\|11354714_11356139_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|214765
NZ_CP022098.1\|WP_157759044.1\|11361939_11362137_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095990995.1\|11357589_11359185_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP022098.1\|WP_095990992.1\|11352045_11354457_+\|exoglucanase	unknown	unknown	gnl\|CDD\|227616
NZ_CP022098.1\|WP_095990987.1\|11344060_11344798_-\|urease-accessory-protein-UreG	unknown	unknown	gnl\|CDD\|349776
NZ_CP022098.1\|WP_095990999.1\|11363304_11365092_-\|thiamine-pyrophosphate-requiring-protein	unknown	unknown	gnl\|CDD\|181344
NZ_CP022098.1\|WP_157759043.1\|11360700_11361471_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|237030
NZ_CP022098.1\|WP_095990988.1\|11344806_11345469_-\|urease-accessory-protein-UreF	unknown	unknown	gnl\|CDD\|223900

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095990984.1\|11339177_11340389_-\|methionine-adenosyltransferase	gnl\|CDD\|235374	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated.	0
NZ_CP022098.1\|WP_095990994.1\|11356340_11357576_+\|chitosanase	gnl\|CDD\|366548	pfam01270, Glyco_hydro_8, Glycosyl hydrolases family 8.	1.30947e-18
NZ_CP022098.1\|WP_095990985.1\|11340620_11341199_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|377516	pfam05494, MlaC, MlaC protein. MlaC is a component of the Mla pathway, an ABC transport system that functions to maintain the asymmetry of the outer membrane. This family of proteins is involved in toluene tolerance, which is mediated by increased cell membrane rigidity resulting from changes in fatty acid and phospholipid compositions, exclusion of toluene from the cell membrane, and removal of intracellular toluene by degradation. Many proteins are involved in these processes.	6.34647e-16
NZ_CP022098.1\|WP_095991000.1\|11365334_11368553_+\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	8.12076e-73
NZ_CP022098.1\|WP_095990990.1\|11347191_11347965_-\|urease-subunit-gamma	gnl\|CDD\|215172	PLN02303, PLN02303, urease.	4.01321e-134
NZ_CP022098.1\|WP_095990998.1\|11362172_11363279_-\|mandelate-racemase	gnl\|CDD\|239444	cd03328, MR_like_3, Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 3. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues, a Lys-X-Lys motif and a conserved histidine-aspartate dyad. This subgroup's function is unknown.	0
NZ_CP022098.1\|WP_095990989.1\|11345479_11347195_-\|urease-subunit-alpha	gnl\|CDD\|237305	PRK13207, ureC, urease subunit alpha; Reviewed.	0
NZ_CP022098.1\|WP_095990986.1\|11341344_11344002_+\|MMPL-family-transporter	gnl\|CDD\|223964	COG1033, COG1033, Predicted exporters of the RND superfamily [General function prediction only].	2.2898e-39
NZ_CP022098.1\|WP_157759042.1\|11359198_11360677_-\|hypothetical-protein	gnl\|CDD\|371915	pfam12138, Spherulin4, Spherulation-specific family 4. This protein is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 250 and 398 amino acids in length. There is a conserved NPG sequence motif and there are two completely conserved G residues that may be functionally important. Starvation will often induce spherulation - the production of spores - and this process may involve DNA-methylation. Changes in the methylation of spherulin4 are associated with the formation of spherules, but these changes are probably transient. Methylation of the gene accompanies its transcriptional activation, and spherulin4 mRNA is only detectable in late spherulating cultures and mature spherules. It is a spherulation-specific protein.	3.77182e-50
NZ_CP022098.1\|WP_095990991.1\|11348968_11350600_-\|cell-division-protein-FtsK	gnl\|CDD\|379799	pfam16227, DUF4886, Domain of unknown function (DUF4886). This domain is mainly found in uncharacterized proteins around 290 residues in length and is mainly found in various Bacteroides species. It has a curved central beta sheet flanked by helices. Distant homolog analysis showed it has a similarity with GDSL-like Lipase/Acylhydrose family. The function of this domain is still unknown.	0.000105222
NZ_CP022098.1\|WP_157759041.1\|11338588_11339107_+\|hypothetical-protein	gnl\|CDD\|237865	PRK14951, PRK14951, DNA polymerase III subunits gamma and tau; Provisional.	0.000123463
NZ_CP022098.1\|WP_095992625.1\|11348059_11348902_-\|urease-accessory-protein-UreD	gnl\|CDD\|376611	pfam01774, UreD, UreD urease accessory protein. UreD is a urease accessory protein. Urease pfam00449 hydrolyzes urea into ammonia and carbamic acid. UreD is involved in activation of the urease enzyme via the UreD-UreF-UreG-urease complex and is required for urease nickel metallocenter assembly. See also UreF pfam01730, UreG pfam01495.	2.20598e-54
NZ_CP022098.1\|WP_095990993.1\|11354714_11356139_+\|hypothetical-protein	gnl\|CDD\|214765	smart00656, Amb_all, Amb_all domain.	2.04379e-27
NZ_CP022098.1\|WP_095990995.1\|11357589_11359185_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.96426e-98
NZ_CP022098.1\|WP_095990992.1\|11352045_11354457_+\|exoglucanase	gnl\|CDD\|227616	COG5297, CelA, Cellobiohydrolase A (1,4-beta-cellobiosidase A) [Carbohydrate transport and metabolism].	1.72669e-171
NZ_CP022098.1\|WP_095990987.1\|11344060_11344798_-\|urease-accessory-protein-UreG	gnl\|CDD\|349776	cd05540, UreG, urease accessory protein UreG. UreG is one of the four accessory proteins of urease. Urease is an enzyme which catalyzes the decomposition of urea to form ammonia and carbon dioxide. Bacterial urease is a trimer of three subunits which are encoded by genes ureA, ureB, and ureC. Up to four accessory proteins (ureD, ureE, ureF, and ureG) are required for urease catalytical function. UreG may play an important role in nickel incorporation of the urease metallocenter. UreG is a member of the Fer4_NifH superfamily which contains an ATP-binding domain. Proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion.	1.07665e-130
NZ_CP022098.1\|WP_095990999.1\|11363304_11365092_-\|thiamine-pyrophosphate-requiring-protein	gnl\|CDD\|181344	PRK08273, PRK08273, thiamine pyrophosphate protein; Provisional.	0
NZ_CP022098.1\|WP_157759043.1\|11360700_11361471_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	4.87928e-05
NZ_CP022098.1\|WP_095990988.1\|11344806_11345469_-\|urease-accessory-protein-UreF	gnl\|CDD\|223900	COG0830, UreF, Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones].	1.30932e-29

>NZ_CP022098.1|WP_095990991.1|11348968_11350600_-|cell-division-protein-FtsK
MRRTRPDESFLVIHPRRTHVLGLAAMSLLAASVGCAGAPEWEQDEVMGTQEAAAGAQGSILFVGNSFTHGHEEPVYSYNKGAITDANNSGQGGVPGIFKKLTVQAGLAYDVTLETVSGETLSGHYATKAAIIGRAWDTVVLQENSTRPLPTARGGNPTDFFTGANNLRNLVLTANPAARVFLYETWASPASVSAQGYTSGTAGLQAMQSDLRTAYFKAYDDFDFTGVARVGDGFLRAVEQGLADPSNGTSAGTFKLWSTSDNRHASKYGSYLSAAVLYAKITGADPRNLSVGAGSAAAELGIGATDASNLNRIAYESATLPDPSGVSIPLPATRASFTGSVTTGTPANLTGNAQLSSLTTSEGTFTNLLGATASGITGTNTPNSRGSTPTNANTAASGLTVNDGANNLGTGNFQFGTAFTAKTRFFIVETALTSGTMGDDTVVTLIDASNNRVGSFSLSLLASQFTASAAGNTSNALATINYTGGVASVTGSPPGSVQSKLGAVTFSLADLGVTNPTSVSTATGLRLVSSTLDPSVVGLYTVP
>NZ_CP022098.1|WP_095992625.1|11348059_11348902_-|urease-accessory-protein-UreD
MPREQTPPVVAARREGSARLAFERVGPRTVVRTALAHSPLRLLTPRNHGHAAWVYTSSLGGGLVDGDHLHMDLEVASGASALLSSQGFTRVYRSPRGCRNELEARVGEGALLALVPDPTVCFTDARYTQRQDIQLAPDASLVLMDLVNAGRSANGERWACASFSSSLRVRQQGRVLLDERWLLEPRHGHLPERLGRFDALGTVLLIGPALASAREALAARVGALPVIPRAGLICSTSPLGPDGIILRAAATFAEALLQQTREWLGFLPSLLGDDPWARRA
>NZ_CP022098.1|WP_095990990.1|11347191_11347965_-|urease-subunit-gamma
MHLSPREIDKLLLHGAGFLAQKRLARGLRLSYPESVALIATQLLEFIRDGRSVAELMDLGRKLLGRAQVMEGVPEMVAEVQVEGTFPDGSKLVTVHHPIEAEHGDLSLALYGSFLPVPSLERFSRAADATAAEQRPGEVIVQPGELVLNEGRDAVTLEVVNKGDRPIQVGSHYPFFETNRALVFDRTQAYGRRLNIPAGTAVRFEPGDPKKVSLVTIAGAQVVRGGNALSSGPMTPENKERALAEVAARGFGHKEGA
>NZ_CP022098.1|WP_095990989.1|11345479_11347195_-|urease-subunit-alpha
MSRKMDRRHYADMFGPTTGDRVRLGDTGLVAQVERDHTVYGDECKFGGGKVLRDGMGQKAGASDAEALDCVITNALIIDWTGIYKADIGIKAGRIAGIGKAGNPDLMAGVTPGMVVGVTTEAIAGEGLIVTAGGFDSHIHFICPQQADEAIASGITTWVGGGTGPATGTNATTCTPGSWYLRRMLESCDTLPLNIGLTGKGNSSRPEGLLEQIAAGAIGLKLHEDWGTTPATIDTCLSMAEGEDVQITIHTDTLNESGFVDDSIAAFKGRTIHTYHSEGAGGGHAPDIIRVCGEPNVLPSSTNPTRPYTVNTLDEHLDMLMVCHHLDREIPEDVAFAESRIRGSTIAAEDVLHDLGAISMMSSDSQAMGRVGEVITRTWQTAHKMREQRGRLREEQGDNDNVRIRRYVAKYTINPAIAHGMAHELGSVEPGKLADLVLWRPAFFGLRPELVIKGGFIAWSQMGDAGASIPTPQPYFMRPMFGARGRATGSTSLAFVSARALAEGTVRGLGLTKQLAAVRRCRGIGKRDMKLNDALPRITVDSETYEVRADGELLVCEPAVRLPLAQRYSLF
>NZ_CP022098.1|WP_095990988.1|11344806_11345469_-|urease-accessory-protein-UreF
MGSSWRVLQLADSGFPTGGFAHSGGLEAAVQHGEVRGREGLERFARELLWQVGHGALPALGAAHREPSQVAVVDARVEAFLTNHVANRASRTQGRAFLDTCARIFPEQVGPLRHAAREAGVRFHHAPLFGAVLRVLEVELLEAQQLLLSLSLRGALSAAVRMGIVGTHESHQLQHQLTPLLDEVLATCGGLGLEALAQTSPLLDLLGSTHDRLYSRLFLS
>NZ_CP022098.1|WP_095990987.1|11344060_11344798_-|urease-accessory-protein-UreG
MHDDEHRGHGQDDADHTHEEWDHPGHFHEREKPHRADFAQRSFTIGIGGPVGSGKTALVLALCRALRDNYRLGVVTNDIFTKEDAEFLVRNQALSPERIKAVETGGCPHAAIREDISHNLLALEELMEELKPELLIVESGGDNLAAQYSRELADYTLYVIDVAGGDKVPRKGGPGITQSDLLIINKTDLAPHVGADLAVMERDARKMRGDGPFVFTQVTKGVGLQSVIDHIIGAWRKATGPASRS
>NZ_CP022098.1|WP_095990986.1|11341344_11344002_+|MMPL-family-transporter
MSDSIHKPPRLALAYASLLVRRPGLVLLVIAALFAVCLWGTTKLTINSNQLDLIDQGLPEVKEVKRIIDMIGGSGHLMLALRGDDEATLKKVADDLGAQLLADKQNVRSVTWKLPVEFIQQNMALFIKTEDLVEGKRRIMAFLKDQIRRANPFFIEIQKTEPVKLDMTDLLNKYGSVGKKSIRDDYNISNDKKMIMMLIKPMWDSNELGKSRAYIEELRQKLTAYSSLPESGGVKLVEDYELMGNKQTVAYGFTGSYKTAVDDSYAIEESLQPVTLLAFAAIFIITIFAFRKWVPTIIVASGTVVGTIITMGFTYVTVGELNMITSILGGLLMGFGIDYGIHFIFRTRLELGQGKRYDQAIRDAVVNAGRPALVAAVVTSGSFFVLMVSEFRGFSQFGFLAGCGTFIIGVLLFAWSPALLSIAGRINPELPRKLIGEMKPPALNSKSGQELRVPKPGLVLGVSTVVVLALCACAINWTSEEIPLDRSTTLWERVKGGVRFNYNSRALIPEGQPSVRLQDEITRRFNISADPIAVYSKTLEEAKAIYEELTQHPDKYNTVDQVVSIYTFVPPPETAAANAKILQEWKEELKDIDVNALPPETQDKAALFMKMLEARPFDVHGVPANYREQFIHLPETKPENHGYLTFIYPAVDLWDGKKMLDFADQTSSIPTPEIKDASGKVIAPAQIHRAAGAAPLFARLARIVLADGKLAVFLVTLWILFMHFLDFRSVSLALASVIPLTVGLAMMLGIMSLADIHLNFMNIIILPILLGFGVSHGLYLLHRFLEGTSPMVALRSVGAAVASSTLTTAAGFAALLVASHNGLKSMGLVACIGLITTLIVSFTVLAAVMQVMWDRRAGQRAASASAPGAPSAPSTDKSDTPEHAA
>NZ_CP022098.1|WP_095990985.1|11340620_11341199_+|ABC-transporter-substrate-binding-protein
MNTRLRSLTLLASLVLCMPALAAESNEAAAKPVKTVVQSVRLSKDDLALKQLADEEMGRFLLGEDWAKGTDAQRKEFTRLFHSLFAKIAFPKVRENFKNLQSITYDPPSVEGNKGNVGSLVIINHPMKKQEMKLKYAVVKDSNAWKVLDVFVLGDSMLTGIRDDQVRPIFQQGGWEHLLDMMRKKDAELSKK
>NZ_CP022098.1|WP_095990984.1|11339177_11340389_-|methionine-adenosyltransferase
MPTDYLFTSESVTEGHPDKIADQISDGVLDAILSKDPQGRVAVETLVKTGLAIVAGEVTTNCYVDIPKIVRSTICRIGYTDSSMGYDGNTCGVMVAIEGQSQDIARGVDNKKEQGAGDQGMMFGFACDETPEFMPAPIHYAHALTRRLADVRRKTHDWLRPDGKSQVTVEYRGGRPVRIDAVVLSTQHSDDISNKKIHEAIREDVIAKALPKKLIDAKTKIYINPTGRFVIGGPMGDSGVTGRKIIVDTYGGMGRHGGGAFSGKDPSKVDRSAAYMGRYIAKNVVAAGLARRCEVQVSYAIGVADPVSVLVETFGTAAVPEEKIVAAIKQTFGLKPREITEHLDLLRPIYQKTAAYGHFGRAEKEFTWERIDKKDALRAFVGLSASAPAPAPVAASTRLKAAV
>NZ_CP022098.1|WP_157759041.1|11338588_11339107_+|hypothetical-protein
MAARGARRRPTAASRPARRWRWGLAALLLLFMLFWLWPSTPEPVPPPVAVPEAPPPPPVVTRPVVKKKVAPKPSPPPPAAPMSSQRALLRRAMEARAPDLRACALPPGAPTTLGARIRVARGGATKSVAFASGQRLPRELAECLRQRLLQWEFSDVGLSSDVEIFVDFALGG
>NZ_CP022098.1|WP_095990992.1|11352045_11354457_+|exoglucanase
MQQTHSNTRSQALRSLPFLLLALCGGVASAETHVDNPFAGASAYINPDYAAQVDSSIAKTTDSTLAAKMRTVKKYPTSVWLDRIVAIHGGSANGGRKSLRDHLDLALAQKKAGQPITASFVIYDMPGRDCHALASNGELPLTAEGLQRYKTEYIDPITTIFADPKYQDVRIVTALEPDGLPNLVTNLSDPACAQAHSTGIYVAAAQYAMNKLHAIPNVYIYMDLGHSGWLGWDDNRQKTIALYTSVVGATTAGLSSVDGFVTNTANYTPLAEPNLVDPNVTVGGQPLRSAKYYEWNPNFDETDFAASLYTGFTSAGWPASIGFLIDTSRNGWGGPNRPTGAYGTTVDTYADSGRIDRRAHRGLWCNQAGTGMGQPPQSTPAGYGGSHLDAFVWVKPPGDSDGASKYIPNNEGKGADPMCDPDFTTQYTTKTNALPNAPLSGHWFHEQFTMLVQNAYPAIPQTAGDNDPALPPTSLTATPGNKQVTISWSGSLGATSYTVKRGSASTGPFATVASVTGTTYSNTGLTNGTTYYFVVSASNANGESANSSPVSATPAEQVLAAPSSLTATAAGSSQISLSWTGSANATGYNIYRSTSPSVAITAANRVGTSSTTSSTQTGLLPSTTYYYKVTAFNAALESAGSNEASATTQAASVGAFSVLYRDGNNNSPITNQFRPHLRVKNGGTTSVSLADIKVRYYISLDGAAALQINCDWALLGCSSMSFQSGQLSAPRPGATHYLEVSFLSGTLAAGQDTGDIQLRVNNTSWSNFNEADDYSYKAGQTAYGDNSNITVYRNGTLAGGLEP
>NZ_CP022098.1|WP_095990993.1|11354714_11356139_+|hypothetical-protein
MNIHFKGMCSLSMALGLAFSAIPATEARAAGVTDYNLTGFSAGNTGGGEISESDTARYKKVYTATELAQALKKGSGVKVVEIMNDLNLGWNELPAAAKVSPFSAHNSALTHPVLLQTGVSKINVDSFSGLTIFSANGARLKHVAITIKRSSNVIIRNLEFDELWEWDEKTKGDYDSNDWDYLTLEESSKVWIDHCTFNKAYDGLVDSKKGTSGVTISWSTFKGDDGSATSFVARQFDALEANKSAYPMYNYLRGSSVGLSRQDITAIAGSQKKGHLVGSTEFASDNPNLSITLHHNYYKDIQDRMPRLRGGNAHAYNIVMDSAGAWAAKNKITSAMATAISSKGYHFTVTSNGAISTESGAVLVEKSHIIDIQYPVRNNQTDPEDASYTGKIRAVDTIDSLNGVVFRGNSDSSGSSLGPVPADVKAFSWNGFSTLPYSYTPEDPSTLKSRLTAADGAGAGKLTWAKSQWLKTSY
>NZ_CP022098.1|WP_095990994.1|11356340_11357576_+|chitosanase
MPMPSLKRLLPGLALTVFGIAGAAQAQNHPFGSHHQTYNASTLSVSAGTAAADSATADFYWKWKSRYVVAGCHAGDYRIKASTGDGAYVVSEGQGYGMLIAVMMAGQDPQAQTIFDGLHRYNLRHPSQNNPDLLAWAQDANCNDILDHDSATDGDLDIAYALLLAHKQWGSNGSINYAAEATRVLNAIAQSNINPTTRLVNLGDWASLLKQDAPDYYYATRSSDWMLGHFRGFIGHASTDWSQVLSAHQTVLEKMQTTYASATGLVPDFIINANTTPRPAPAEFLEAPYDGSYSWNACRVPWRIGIDAAISGDTRSRNAASLISRWIRGKTGGKPNSIRAGYQLNGTALESYNDMVFMAPFAVAATVDSGGQAWLDSLWNQIVSTAPTEDYYGDTIKLLAMLSVSRNWMTP
>NZ_CP022098.1|WP_095990995.1|11357589_11359185_-|serine/threonine-protein-kinase
MTQVQLPQLGKYRLLEVIAKGGMGEVYKAQQEGPAGFSKTVVVKRVLPHLADAENFIDMFLEEARLAARLSHPNVVQIFELGEDRGEYFIAMEYIQGPSLHRVRKRLRELGHPFPVDIAAYVVAQALQGLHYAHELRDEAGKPLGIVHRDISPDNILVTMDGVVKVVDFGIAKAADSSSKTQSGTLKGKLSYISPEQVNGWPASVHSDIYATGVVLYQLFTNTLPFRAPSNAALLQQIATAEPEAPDRLELDVPPVLSRIVMKALRKEPGERFATAQEMSRALLEALESCQRRLFPEDLGAFLKQLFEQEGSPRRFFAQPTPRGTGRSSPPMVVEDEATAPLAGPVLSNPPTVTMESARPRNRAIAWAVGGALLSVAVGVVALRPWERGTPPAPAPVAPSSEAPAPAPENVQAQKPVTPEPSPEKAAVPPPREAAPPPDEPTPEPTTPSPAPSPQEPSRVAAMGRVQVRVNPWAEVFYEGHRLGITPMPAIRLPAGRRTLTLKNKELGVSRDYRVSVPANGEVTLKADLLE
>NZ_CP022098.1|WP_157759042.1|11359198_11360677_-|hypothetical-protein
MNRDTRVALSFLLLGLLFAPGCLVQSIDEEGRACDVEHPCSAGRSCVEGVCLSHVTPAADGGPSEQGDGGPADGGESCLDACVDWLCGTSNACGAVCQPVNGCVEGSLLDGFEPGGTGWIIFKDESTTFQMTAVSSPALSGQALRLDYDINPAGGFGGIERLLGEGQDWRQATGLGIWVYGASTGHPFRLELYDTHRVRFEFSVAVDWTGWKHVYAPFSAFTLSGFQTVPDAGSATLALDAVKGLSISPGYLSGAHGSVVVDELALLQRPEAGAIVPLYIYPSPGAWAPLIEGKAAHPTVPVLAIINPDTGPGAAINPEYVTSISALADAGITVLGYVHASYSQRDEGLVREDINRYRSFYPETRGIFIDEMANTQGQEGYYRALSDHARDAGFSLTVGNPGARTPVSFRGTVDVLTISEGPGLTDAGLIHEAAAGFDRSSLSVLRYGLPTASPAYVNQVRRDVRYIYLTHDAQNPWTSLPPYLNNLLASLR
>NZ_CP022098.1|WP_157759043.1|11360700_11361471_-|tetratricopeptide-repeat-protein
MRAVLGWIAIVQLLWAGSARADELATLALSQAKAFYQALDYERCLKRLKRAGTLKLSEPERAEVALYQGLCGAGLGQSKAARKSFQRALELDPQLQLPLGTSPRIVELFEEVGGKRRTRPAEAPAVAAAPAPAAPAADVPSASPAEPPAVTPGLKPAAPPVVTERPAFLPQAQPPKSGVVRAMPYVLGGASLAVLATGVVFGVQARSFESQARGAHFDSDMASFNRQAASRARTANILFVGSGVVAAATVVSALLQ
>NZ_CP022098.1|WP_157759044.1|11361939_11362137_+|hypothetical-protein
MSHDEVNELGETLRIPRTEFLEVIDKMQLERLVSVTFGGLSLTPEGRALAAKMDGTGTRGSVEVQ
>NZ_CP022098.1|WP_095990998.1|11362172_11363279_-|mandelate-racemase
MGQTRGEAVPIERCEARAYEIPTDAPEADGTVEWNSTTLVVVEVTAGGRRGLGYTYADASAASLIHHTLSKELEGLDVMDVPARMVSLLRRVRNKGRPGLVAMALSAVDAALWDTKARLLDMPLVRLLGAARAAVPVYGSGGFTSYSIAKLKEQLGGWVAQGIPRVKMKVGSHPDEDGHRVREAREAIGPEAWLFVDGNGAYTVKQALVLADSFAEAGVVWFEEPVSSDDLEGLHLLRQRIPSGMNVAAGEYGWDAIYFRRMLGARAVDVLQADATRCLGVTGFLQVDALCEGFQVPLSGHCAPSLHLHVACAARNLVHLEYFHDHVRIEHLLFDGARSPVKGALTPDLSRPGMGLELKRRDAERYAL
>NZ_CP022098.1|WP_095990999.1|11363304_11365092_-|thiamine-pyrophosphate-requiring-protein
MSATVSDYLLYRLTQWGIRRLYGYPGDGINGLLGALGRNSEFQFIQARHEEMAAFMACAHAKFTGEVGVCVATSGPGAIHLLNGLYDAKLDHQPVVAIVGQQKSMGLGGHYQQEVDLPVLFKDVASEYTVMVSNPSAIRHAVDRAVRIAQSQRTVTCIIIPNDVQEQPYQRPPQVHGSIHSSVGYSEPRVVPQEKDLRRAAEVLNAGKKVAMLVGAGAMRAADEIIEVADLLGAGVAKALLGKAVLPDDLPFVTGAIGLLGTKPSWDMMMECDTLLMVGTSFPYSEFLPPEGQARGVQIDIDGRMLAIRYPMEVPLTGDSKETLRALVPLLKRKEDRGWREGLEKGIRQWWKVVEGRAMNGANPINPQRVFHELSPKLPDGAILSSDSGSAANWFARDLKIRKGMMASLSGNLATMGCGVPYAIGAKFAYPDRPVIAMVGDGAMQMNGNGELVTIAKYWKEWKDPRLVILVLNNRDLNQVTWEQRVLAGDPRYKASQELPDFPYARYAESIGLRGIRVDKPEQIASAWDQALSADRPVVLEAYTDPDVPPLPPHITLEQARHFSEALLKGDEKSVGLIRQSIKGMVEQLRPHKKD
>NZ_CP022098.1|WP_095991000.1|11365334_11368553_+|FAD-binding-oxidoreductase
MRTRDAIQRALSKVPRKQPSPRTLPGTQGGEVMLDVRGLEADLRRSVKGEVRFDDGSRALYATDGSNYRQVPIGVVIPRSIEDVIQTVRVCREHGAPLLSRGGGTSLAGQCCNVAVVIDWMKYLGKVLEIDPATKSARVQPGTILDVLRHQAEEYHLTFGPDPSTHNHCALGGMLGNNACGSHAQMAGPVSHNVLELDVLTYDGLRLKVGPTSDEELQAIIRSGGRRGDIYRKLRDLRDHYADEIRRRYPPIPRRISGYNLNALLPENGFDVARALVGTEGTCVTILEAKLRLVHSPPHRVLVLLGYPDIYTAGDHAHELAERFHPLALEGLDYRLIHNVVVKGHTTELASIHPKSSHVEFLDLLPRGHGYLMLELGGDTKEEAIERAREMMDELCADRRPPEDMRLYSDMEHIEHAWKIRESGLGATARVPGQPDTWPGWEDSAVPPEKLGDYLRGMRKLYDKYGYDASLYGHFGQACVHTRINFDLKSARGIQQYRAFMSEAVDLCVSMGGSLSGEHGDGQARAEFLPRMFGPELVRAFREFKTIWDPLGKMNPGKVVDPHPIDQQLRFGRDYEARTWKPKTHFKYPDDDGLLYRATERCVGVGKCRRDSGGTMCPSYMVTKEEKHTTRGRAHLLFEMMQGQVIKKGWRDENVKESLDLCLACKGCKGDCPVNVDLATYKAEFLSHYYQGHLRPRTAYSMGLIMFWARAAMLAPGLVNLLTQHSPTQELLKKLGGITTKRPMPRFAPESFQRWVVRQRPVPRHQGHQRVLLWPDTFNNHFFPETAASALEVLEDAGFEVVVPQGFLCCGRPLYDFGMLPTAKWMLRRTVERLRPYIEKGVPLVGLEPSCVSVFRDELRNLFPDWSLATQLRRQTFLFSDFLGRYARDWQPPRLEKKAVVHGHCHHKSLFKMNDEKGLLEKLGLDYQVPETGCCGMAGSFGFEAGEKYEVSQKVGERVLLPKVRETPKDTLLIADGFSCREQIAQNTDRKALHVAQVVRMAKASGSTGPAGEYPERGWVTSGLGKPPARWGLRAAVVGTGLLLGGLWLLRWPGNTRAHSRKRPPSRTPNTT

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_22

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_22

11610246-11610344

Orphan

Consensus_repeat	Method
TGTAGCACGCGTCCGAGGCCGAAAATTCGGCTCC	CRISPRCasFinder

1 spacers

DinG

The CRISPR arrays of NZ_CP022098_22

>merge|NZ_CP022098|22|11610246-11610344|CRISPRCasFinder
TGTAGCACGCGTCCGAGGCCGAAAATTCGGCTCCGCATCGCACAGCAACACACCAGCATCAGGTATGTAGCACGCATCCGAGGCCGAAAATTCGGCTCC

>NZ_CP022098|22|20|11610246-11610344|CRISPRCasFinder
TGTAGCACGCGTCCGAGGCCGAAAATTCGGCTCC	GCATCGCACAGCAACACACCAGCATCAGGTA
TGTAGCACGCATCCGAGGCCGAAAATTCGGCTCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_095991163.1\|11603193_11604330_+\|epoxide-hydrolase	unknown	unknown	gnl\|CDD\|377658
NZ_CP022098.1\|WP_095991165.1\|11609547_11610147_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095991170.1\|11615488_11615851_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239532
NZ_CP022098.1\|WP_095992644.1\|11612063_11613014_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|132002
NZ_CP022098.1\|WP_095991166.1\|11610771_11612067_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224154
NZ_CP022098.1\|WP_043430744.1\|11596863_11597400_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP022098.1\|WP_095991159.1\|11594394_11595873_-\|histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP022098.1\|WP_095991171.1\|11615938_11616469_+\|polymer-forming-cytoskeletal-protein	unknown	unknown	gnl\|CDD\|377376
NZ_CP022098.1\|WP_157759062.1\|11619487_11620192_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_157759061.1\|11605082_11606150_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095991161.1\|11599306_11600437_+\|PilT/PilU-family-type-4a-pilus-ATPase	unknown	unknown	gnl\|CDD\|225364
NZ_CP022098.1\|WP_095991164.1\|11607763_11609122_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095991160.1\|11595869_11596574_-\|MglA-protein	unknown	unknown	gnl\|CDD\|225138
NZ_CP022098.1\|WP_095991173.1\|11617629_11618988_-\|hydrolase	unknown	unknown	gnl\|CDD\|185683
NZ_CP022098.1\|WP_095991167.1\|11613187_11614108_+\|endo-alpha-1,4-polygalactosaminidase	unknown	unknown	gnl\|CDD\|377061
NZ_CP022098.1\|WP_095991839.1\|11606400_11607552_+\|IS4-family-transposase	unknown	unknown	unknown
NZ_CP022098.1\|WP_095992643.1\|11600446_11602435_-\|ATP-dependent-DNA-helicase	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|224120
NZ_CP022098.1\|WP_095991169.1\|11615069_11615492_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372545
NZ_CP022098.1\|WP_095991172.1\|11616503_11617607_+\|ankyrin-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|293786
NZ_CP022098.1\|WP_095991168.1\|11614168_11614861_-\|NAD(P)-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|224996

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095991163.1\|11603193_11604330_+\|epoxide-hydrolase	gnl\|CDD\|377658	pfam06441, EHN, Epoxide hydrolase N-terminus. This family represents the N-terminal region of the eukaryotic epoxide hydrolase protein. Epoxide hydrolases (EC:3.3.2.3) comprise a group of functionally related enzymes that catalyze the addition of water to oxirane compounds (epoxides), thereby usually generating vicinal trans-diols. EHs have been found in all types of living organisms, including mammals, invertebrates, plants, fungi and bacteria. In animals, the major interest in EH is directed towards their detoxification capacity for epoxides since they are important safeguards against the cytotoxic and genotoxic potential of oxirane derivatives that are often reactive electrophiles because of the high tension of the three-membered ring system and the strong polarization of the C--O bonds. This is of significant relevance because epoxides are frequent intermediary metabolites which arise during the biotransformation of foreign compounds. This family is often found in conjunction with pfam00561.	2.15232e-58
NZ_CP022098.1\|WP_095991173.1\|11617629_11618988_-\|hydrolase	gnl\|CDD\|185683	cd00413, Glyco_hydrolase_16, glycosyl hydrolase family 16. The O-Glycosyl hydrolases are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A glycosyl hydrolase classification system based on sequence similarity has led to the definition of more than 95 different families inlcuding glycosyl hydrolase family 16. Family 16 includes lichenase, xyloglucan endotransglycosylase (XET), beta-agarase, kappa-carrageenase, endo-beta-1,3-glucanase, endo-beta-1,3-1,4-glucanase, and endo-beta-galactosidase, all of which have a conserved jelly roll fold with a deep active site channel harboring the catalytic residues.	2.42182e-20
NZ_CP022098.1\|WP_095992644.1\|11612063_11613014_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|132002	TIGR02957, putative_sigma_factor, RNA polymerase sigma-70 factor, TIGR02957 family. This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building and bidirectional best hits, to represent a conserved family. This family is found in a limited number of bacterial lineages. This family includes apparent paralogous expansion in Streptomyces coelicolor A3(2), and multiple copies in Mycobacterium smegmatis MC2, Streptomyces avermitilis MA-4680 and Nocardia farcinica IFM10152.	6.29977e-56
NZ_CP022098.1\|WP_095991166.1\|11610771_11612067_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	1.16701e-31
NZ_CP022098.1\|WP_043430744.1\|11596863_11597400_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.59814e-16
NZ_CP022098.1\|WP_095991159.1\|11594394_11595873_-\|histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.04456e-65
NZ_CP022098.1\|WP_095991171.1\|11615938_11616469_+\|polymer-forming-cytoskeletal-protein	gnl\|CDD\|377376	pfam04519, Bactofilin, Polymer-forming cytoskeletal. This is a family of bactofilins, a functionally diverse class of cytoskeletal, polymer-forming, proteins that is widely conserved among bacteria. In the example species C. crescentus, two bactofilins assemble into a membrane-associated laminar structure that shows cell-cycle-dependent polar localization and acts as a platform for the recruitment of a cell wall biosynthetic enzyme involved in polar morphogenesis. Bactofilins display distinct subcellular distributions and dynamics in different bacterial species, suggesting that they are versatile structural elements that have adopted a range of different cellular functions.	0.000966035
NZ_CP022098.1\|WP_095991170.1\|11615488_11615851_+\|hypothetical-protein	gnl\|CDD\|239532	cd03448, HDE_HSD, HDE_HSD The R-hydratase-like hot dog fold of the 17-beta-hydroxysteriod dehydrogenase (HSD), and Hydratase-Dehydrogenase-Epimerase (HDE) proteins. Other enzymes with this fold include MaoC dehydratase, and the fatty acid synthase beta subunit.	2.95493e-08
NZ_CP022098.1\|WP_095991161.1\|11599306_11600437_+\|PilT/PilU-family-type-4a-pilus-ATPase	gnl\|CDD\|225364	COG2805, PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion].	1.39173e-154
NZ_CP022098.1\|WP_095991160.1\|11595869_11596574_-\|MglA-protein	gnl\|CDD\|225138	COG2229, COG2229, Predicted GTPase [General function prediction only].	6.17923e-11
NZ_CP022098.1\|WP_095991167.1\|11613187_11614108_+\|endo-alpha-1,4-polygalactosaminidase	gnl\|CDD\|377061	pfam03537, Glyco_hydro_114, Glycoside-hydrolase family GH114. This family is recognized as a glycosyl-hydrolase family, number 114. It is endo-alpha-1,4-polygalactosaminidase, a rare enzyme. It is proposed to be TIM-barrel, the most common structure amongst the catalytic domains of glycosyl-hydrolases.	7.55671e-70
NZ_CP022098.1\|WP_095992643.1\|11600446_11602435_-\|ATP-dependent-DNA-helicase	gnl\|CDD\|224120	COG1199, DinG, Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair].	1.68979e-156
NZ_CP022098.1\|WP_095991169.1\|11615069_11615492_+\|hypothetical-protein	gnl\|CDD\|372545	pfam13279, 4HBT_2, Thioesterase-like superfamily. This family contains a wide variety of enzymes, principally thioesterases. These enzymes are part of the Hotdog fold superfamily.	0.00302295
NZ_CP022098.1\|WP_095991172.1\|11616503_11617607_+\|ankyrin-repeat-domain-containing-protein	gnl\|CDD\|293786	sd00045, ANK, ankyrin repeats. Ankyrin repeats are one of the most abundant repeat motifs, and generally function as scaffolds for protein-protein interactions in processes including cell cycle, transcriptional regulation, signal transduction, vesicular trafficking, and inflammatory response. Although predominantly found in eukaryotic proteins, they are also found in some bacterial and viral proteins. Less is known of their physiological roles in prokaryotes. Some bacterial ANK proteins play key roles in microbial pathogenesis by mimicking or manipulating host function(s). The pathogen Providencia alcalifaciens N-formyltransferase ankyrin repeats function in small molecule binding and allosteric control. Ankyrin-repeat proteins have been associated with a number of human diseases.	9.06393e-18
NZ_CP022098.1\|WP_095991168.1\|11614168_11614861_-\|NAD(P)-binding-domain-containing-protein	gnl\|CDD\|224996	COG2085, COG2085, Predicted dinucleotide-binding enzymes [General function prediction only].	1.62757e-46

>NZ_CP022098.1|WP_095991165.1|11609547_11610147_-|hypothetical-protein
MAPSNTTSGLDHATDQAGPLLGAEVGAIAPQHAFRSAEQQRHGAKLQKAILAIWGSSARPFAVGGVVTAQFFYLLSKFPEGLLWGPIELPGVGLGTSVAFASFTGSLVVGGTVNLVKIIAPPLHHYWGLFEVWSKYLLGRISPEQYFEHGAVLDYQRLYGHMPSDSRPETQAEFVRRVVQWRRKRKLGNRKGRAKAPVS
>NZ_CP022098.1|WP_095991164.1|11607763_11609122_-|hypothetical-protein
MRSILPTIVLLHSVVIAVIGATPAHAQLETTLTIGAVSNALSNAITDFKSSLETVGGEVRGVGNSLQANAQNVISDIDRVFGRNVNLTFDRMDAQQRALYRDAQALTRQVRDATTALATKTGDELRRTIAEADISAYNISYSLPCRTQTPRIVYVATPRLRLGRDTPEITIRGNFLDWPAASEVTVDGTPARVIARSAGELRVAVPDAIVGAITAERSVALRVPAENRKRKIFLFCSTTKERLELQASATLVPRRQVSISAWIKPTTLVAETRKQLHNYDSGKSGDCDINTDVSQQVCAAEGWQVSDITHFAETGKNCGSNAGPPNVSGARCVHVPARLRGCGYRKYLGVKECKGRGWLSWDMSVGLTRDVRQDAQLQSFTVNAEGQSSWSFHYKPSENLRGPTWSYGARVQVAEGNKIEVYEVSQAQENAGPVSARLIDGTLAITLNDGSL
>NZ_CP022098.1|WP_095991839.1|11606400_11607552_+|IS4-family-transposase
MRKPRLDDQQVHTFLESLFEEDLHAKRVLSLAYAVLGVIHAASLGVHLIGKALAWARGTKSKHGVKQVDRLLSNQGIDVWALFAQWVPFALGQRSEALVALDWTDFDADGQTTLVASLVASHGRTTPLVWLTVEKSALEGMRNDVEDFVLNRLRQVVPERVRLTLLADRGFGDQKFYALLEQLKFDYVVRFRQCIQVMDETGEKKSAGEWVPESGRAVRMVGARVTQDEAPVGAVVCVKQKGMKEAWCLATSLKEATAAFVVGLYGKRFRTEETFRDMKDLRFGMGLSSVRVRSTERRDRLLLVSALACALLTLLGAAGESLGMERYLKANTVKTRTYSLFRQGCEYYQAIPMMPEEQLVPLMKRFASLLREQPVFQEFLGPI
>NZ_CP022098.1|WP_157759061.1|11605082_11606150_+|hypothetical-protein
MADNREAVVIPSLCEILNITPAASRQDDLLHALARINAPQTICAAAKAEVGFTDFYAPFRNTSWNWMTTHATKIRPLMVAARRLKSDSSASSLYDLISQLPPIPRKVGGPLPAANLLTPLVACLDPRARAPIINSAKSVTLALKQLGLFHATLSEKFSGLVGLIGQAGIEDAFFLDVCLDLLGKTVLGKAVDPIDSQKAEKLTQEPPKKDGANSAPLGLKDAEDLKVISLGGTKKRAQLHNKMTNRLLALCKKHKLTVDEGSDKACRYDARIQNYAKGRDLLIEAKTSTEIADSRLAVGQLLDYRRHLAKRASTDIAVLLPQRPDSKVMNFLDDVGVKLIWFKEDFKSITGEIEL
>NZ_CP022098.1|WP_095991163.1|11603193_11604330_+|epoxide-hydrolase
MSPRPFRIDVPQAVLTDLQRRLEATRFPEPLPGEPWQRGADVAYVRELCAYWRERYDWRKHEAELNRFPQFLCEVEGVDLHFWHVRGKGPSPLPLLLTHGWPGSIYEFHHLIEPLTDPAAYGGDARDAFDVIIPALPGYGFSGKPREPGWDATRVAAVFDRLMVEHLGYSRYGAQGGDWGGVVTTALGVEHAEHLVGIHLNFALASPPPGQEQSELAREYGQKMAAFSAAESGYSHVQGTKPMSLGIGQADSPAGLAAWIVEKFRTWSDCGGDVERAFSKDWLLTNLMFYWAPNSIASAANLYYETFGMQRLDLKKPVRVPTAIADFPKELTHTPRPWLEARFNLRRYTEMPRGGHFAAAEQPELFLKDVRSFFRELR
>NZ_CP022098.1|WP_095992643.1|11600446_11602435_-|ATP-dependent-DNA-helicase
MALPASSHLPSVDSLLGPGGALEVALEAYEYRPEQLQMARSVERAFQERGYLLAEAGTGTGKTLAYLVPALLSGRRVVVSTATKTLQEQIFFKDLPLLRERMGLSFEAVYLKGRSNYLCLHRYDAFSKDPQFASREEGRYWKHLKTWAGSTETGDRSELELPESFSAWGRLSTTSDTCLGSKCPVYDNCFVTRVRRAAESADLLVVNHHLFFADLALRGRGQRGEGVLPPYDAVIFDEAHALEDAAGSYFGHSVSSFRLEELVRDALGVMSPQDSRFGMLSSLVVRLRTYSEALFSQAPRVLGLTEQEGAVALKPERLEQLSGSIEQVKESLSALSAFTTTEREAELTLLTRRCADLVADFSFLQKVESNDHVYWAEARGRGVFLRASPIEVSRELQERLYGGVDTVVFTSATLAAAGRFDFFARRMGLYDDEGTPVTSVRTVAVPSPFDFERQSALYLPTHLPDPAAPGFIEAVAEEIVRLCEVTGGRAFVLFTSLRNMERAHALARHRLPYQVLLQGERPKQQLLEAFRSQPSVLFAAHSFWEGVDVPGDALSLVIIDRLPFASPGDPLVAARIRQLEARGEAPFGGYQLPQAALALRQGFGRLIRTRADRGIVALLDRRIVTKSYGRSFLASLPPAWRTHSPESLEAWFHGEPVYDVEE
>NZ_CP022098.1|WP_095991161.1|11599306_11600437_+|PilT/PilU-family-type-4a-pilus-ATPase
MSSSSASPRIAAFFDKLLEHKGSDLHLSIGHPPLGRIRGGLQPLREELLTQRELEAMLFELTSPEQKRHITEELDLDFAYSYGTRARFRANYFYKTSGIAAVFRTIPSRVLSLAELNTPEVVRKLAERRSGLVLVTGPTGSGKSTTLAGMIHHINHTRAAHILTIEDPVEFVHESVKSQVTHREVGLHASSFATAIRSAGREDPNVILIGELRTNETMKLALQLASYGVLVFATVHTNSAPATIDRIINSFPADEQPQVRGMLAEGLAGIVAQQLIRTADGKGRVAALEILIGTSAIASMIRDNKVFQIASKMQSSQGLGMQTLDMHLERLVAANTITPEAALEKAQDKESFAKTIRRLKPDFQVSAADGGEALGH
>NZ_CP022098.1|WP_043430744.1|11596863_11597400_+|GNAT-family-N-acetyltransferase
MTMKRVEPGVEVGAMPVPDMTTMPNDLALAVKFNAPSDEDMASVAALRANSEPWLSRGETLEDSLKALTGLRPFVQVAKVQNQVVGYVTVERDGPVPGAAYMRNIVIKPELRRKGVGLAVLNQALQVARDMYRKTIALRVDPANAPAVSFYRNAGFTTVATVVSKKSGKLRLLMSREL
>NZ_CP022098.1|WP_095991160.1|11595869_11596574_-|MglA-protein
MQLNHAQRELTLKIVYYGPGLSGKTTNLRCIHARARPEARGRLLSVETHEDRTLFFDLLPVFFTSQSGFKVKLKLFTVPGQVVHDATRRVVLQNADAVAFIADSRRSAGAENNASWRRLRANMRENGLDTSQVPVVIQFNKRDLPDAQTDEELEAARQRGTEPIVGAVALRGEGVMETLHALLQSAWRNLDERMRLARNIGLEEREFLGHIFQQMDLKGTPLEALYPPAGGKQR
>NZ_CP022098.1|WP_095991159.1|11594394_11595873_-|histidine-kinase
MSAEKPGPAGNGSEPTGLALQRKLSLVDLLDPLTFGDVVESLGALYQVGVRVLDERNRTLADTQGAQGEFCGFIGANPAVRVRCSAQVTRVKEGPLAGLLSSQVLGTEGAGELLLHTCLTGLCYVVVPVVWEGDVLGRVVFGPYVSEEGGTPGCPEGPDAERVREARARARHLSQEELARMVKHLAQVLAALLAAGQKSYLTGQLHLEAMVETQRELEHQNSQLLRLNQRLKESDRSKSSFLSTVSHELRTPLASIIGYSEMLAEGLVGGLNPEQMQFVRTIMEKGNTLLKLISSILDMSQIEAGKVRLAFEWVDVREMVESAITSVTPQAQRKGLTLEANLPVGPQPRVVADREKLRQVVVNLLANAVKFTPSMGRIDVRLSEVGTRSELATAGYHIEVEDTGVGIPENQRDRIFQSFYQVDDSPTREYGGAGLGLAIVKSYVEGHGGQVSVRSEVGKGSCFRVVLPKEPPLSGQGPAYIPPPVDTEPERF
>NZ_CP022098.1|WP_095991166.1|11610771_11612067_+|FAD-dependent-oxidoreductase
MKTTDVAVVGGGLGGLAVATLLARGGRRVVLFEKARHLGGRAHTTHQEGYHLNLGPHALYMAGAAARVLGRLGLELRGRGPRGEGGFALRGGRLHTLPSGLVSLLTTDLLSTMGKLEFARVMANLMRVDASTLKGMSLEEWLCANVSREEVRDPVAMLFRVSTYCADLALLGADAAVAQHQAAMAQGVRYLDGGWVELVRGLSAIADAAGVERVLSARVEEVTREEGGGRPRVHGVRLADGTEWAAEAVVLAAGPQDVAALLPGDAVAAGWAAKAVPVKAATLEVGLSRLPRPGALIAFGVDRPWYASVHSAWARVAPEGGALVHVAKYLGERDAVASEPELEGVLELLQPGWRQHVVTRRFLPGLTVMHALPTKTEGLEGRPRPVVEHLQGLGLVGDWVGPEGMLVDASLSSAEAVARAWLGRAEGARAA
>NZ_CP022098.1|WP_095992644.1|11612063_11613014_+|sigma-70-family-RNA-polymerase-sigma-factor
MTSVDHEALEHAAREHERFLWGLCYRMTGVAADADELVQETYARALATPPGQPEEMRPWLTRVAMNLARDRLRRRKREDYVGPWLPSPVETGEEAVASVEAHLSGGGTTEGRYELLESVTFAFLLALEALTPRQRAVLLLRDVFDYPVREVAECLRMSETNVKVTHHRARAVMAAYDRERCVPTRELQERTRRTLEDFLGALVSGDVAAAEALLAEPVRALSDGGGETFAARVPVVGIKRVALFYRRLHELGGVADALEVRMINGLPALVAHWMQPAPGRPKRVVIRLDIGEDGRVRVLHSVQASRKLTGLPASTS
>NZ_CP022098.1|WP_095991167.1|11613187_11614108_+|endo-alpha-1,4-polygalactosaminidase
MSKLSLVAALTLGPLLGCGIQSTPSEPNPDGSIGAERLDAGAPLSDAGTPTSWWRPTPAQPIHWHWQLSQDFSYPRDVLPNKTVYDLDGELTSAETVAKLHALGPDIVVICYFDAGVYEDYRSDKARFPASVIGKPDEGWDGSYWLDIRQQDILLPIMRDRMINWCKNKGFDAIEPDETEVWSNDSGFPITKAQNNAYNKAIADLAHSLGMSVGLKGNNTEAPELVDYFDWALTEQCWEYDECQLFKNSFFAKGKAVFNVEYNTNPNCTLANQWHINSSRRDLDLVGPTASGYLYQPCIPDTQSTW
>NZ_CP022098.1|WP_095991168.1|11614168_11614861_-|NAD(P)-binding-domain-containing-protein
MKIGIIGAGMIGGTLARRWTRLGHEVFIANSRGPETLRELAAETGAKAVTPAEAARAGEVVVLTIPQKAILDLPKDLFANVPKDVVVIDTGNYYPIRDGQIAELDGGKVESEWVASRIGRPVVKVFNNIYFKNLLEKGTAKGTPGRIALPVAGDPPEARAKVLRLVDELGFDPVDAGSLSDSWRQQPGTPSYTHDLDAARLKQALAAAERGSIPEYRNAANESLKKYLTT
>NZ_CP022098.1|WP_095991169.1|11615069_11615492_+|hypothetical-protein
MSRFEPITLPTGRYALTAATDDAIRGSCGAPARAGQAAHPIMAFVAAVGGLGASVAEVCRLCGSSVDVGPVLASCAIRYPREMRIDQEYRVEARLADVVRKPSHRFGEADHARLEIALMQGEDIHAEVSLHWILPVRGEA
>NZ_CP022098.1|WP_095991170.1|11615488_11615851_+|hypothetical-protein
MSALPPIRIDAVEAAPMVVWVRAMNDDNPIHVDPAVADALGFGPRTVNPGPMNLAYAMNLLLAATPDRPIAAIEARFLGNVQSGDSVRAEGTQEGDTATLRLVRAEDGAVLVDAVARLRE
>NZ_CP022098.1|WP_095991171.1|11615938_11616469_+|polymer-forming-cytoskeletal-protein
MNILPSLLEPHAALLSPALNRLDELDAEGLLAAPVDLEAMVQHGVDSRPRLDGQRLEFDEPTCVVVTGDVTAETLVLEEQSVLLVLGNLKARSARLYGTALVLGTCEVTESLVGHGEPHTLTVLGAVQAGRCEMHQQYIMQFLGGGTLASLSDSEGGEEELLELMHAAGSALQVGA
>NZ_CP022098.1|WP_095991172.1|11616503_11617607_+|ankyrin-repeat-domain-containing-protein
MTKQQTELIDLIRKINDLHYIETYNRVEKPEAEYLAILRKAQDGNAAILDSIRQLLAEGVSLDFKTINGHTPLAVAVTQNNVELVQLLIAHGADIHSTMGYDTPLHRAAEFGADRVVRFLIEKGLDPRAKTPGGRSVLSAARSSRHSKNVVPLLVELLKKTKSQRPPPPKKLKELSEENVTRYLAGTAPATVAARDWEALQAFMDSVFVEEHSVTIDQLYENIEEHGGTRPHLVFACIDLIQKAATREPQHKKLKKVSKTTYVHHGDLEIDGDLGVRSLMVTGSLTVKGKASNPQGRQLFVGGDFACDTFYTEGPVVIGGDLRARTVDAFYNDYGLEVRGTLKADTLTVERHQVTAGRFDVRERIDK
>NZ_CP022098.1|WP_095991173.1|11617629_11618988_-|hydrolase
MKTIWKQSLLAAMSLVVPLSESLAGTADFTVQYQNYNAAGPNDDIIEAGIQVRNNTSAAIPLSNIVVRYWLTKNGATTVAPACWWWNAPSCSAISLSTGSASATGADQYVEIRFTSAAGSLAAGATTAPIDLGVTFGGATVNETDDYSYGNQTVPTDWSRITVHDAGSAPTGGLRGGTLPTGGTNPPTDPPPSNLAEFFDDFTYSGTGDAAFTNLWTVRTYAGGPGVSGATWSASNVSIVTEGSDRLMRLRATTNGTTAGTSHSEVLTQAQKFRFGTYATRMRFRDTPLSGTRVFADKYVETFFALTPYSSPSYSEQDYEYLPNGGWGQGNTPTMFLTSFDKNKTASTSARLAYSHDGWHTLVLHVTPSGNVYHIDGVERANHSSQFSPLINQFLDFQMWFIELGASGGARTYFEDVDWVYFAKDAYLDTNTVNAKVSSLRGASIPRKDTVP
>NZ_CP022098.1|WP_157759062.1|11619487_11620192_-|hypothetical-protein
MKEALKIVVPNVDLNPNRIKIEPLPENDRALQGTRANSWKEEPPTRDSIVLFGAIAARLMESGGFVVFHFDTDRVWAERDTSENRQKFESIIRERVRKILRGEATPPPPSGRGTHLALTPEEIEAALARLLVLSPCYSIESWLYQSTQELLAHCQERHTSAEHVQRIESWSADRRLLDEVSRPKKALLPCIGDLHNEALAKTFPADEVWLAERSFFESVERLRACSSLVEALGS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP022098_23

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022098_23

11839841-11839941

Orphan

Consensus_repeat	Method
GAGACGGACAGTTTGGAATGTAGTCCC	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of NZ_CP022098_23

>merge|NZ_CP022098|23|11839841-11839941|CRISPRCasFinder
GAGACGGACAGTTTGGAATGTAGTCCCGTTCGCATTCGGCCTCCCTCCTCCGCCGTGGCCGGCAAGGGGTGAGTGAGACGGACAGTTTGGAATGTAGTCCC

>NZ_CP022098|23|21|11839841-11839941|CRISPRCasFinder
GAGACGGACAGTTTGGAATGTAGTCCC	GTTCGCATTCGGCCTCCCTCCTCCGCCGTGGCCGGCAAGGGGTGAGT
GAGACGGACAGTTTGGAATGTAGTCCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022098.1\|WP_095991349.1\|11845364_11846069_-\|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NZ_CP022098.1\|WP_095991354.1\|11850042_11851935_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238020
NZ_CP022098.1\|WP_095991353.1\|11848598_11849411_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095991346.1\|11839966_11841523_-\|TROVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|368584
NZ_CP022098.1\|WP_095991345.1\|11838464_11839739_+\|tyrosine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235645
NZ_CP022098.1\|WP_095991343.1\|11836249_11837170_-\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|235737
NZ_CP022098.1\|WP_095991350.1\|11846163_11846565_+\|glyoxalase	unknown	unknown	gnl\|CDD\|319925
NZ_CP022098.1\|WP_095992663.1\|11849407_11849617_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022098.1\|WP_095991340.1\|11833963_11834851_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212492
NZ_CP022098.1\|WP_095991351.1\|11846627_11847515_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP022098.1\|WP_095991336.1\|11830812_11831205_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227936
NZ_CP022098.1\|WP_095991339.1\|11832944_11833967_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|293841
NZ_CP022098.1\|WP_095991341.1\|11834886_11835594_-\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_CP022098.1\|WP_095991352.1\|11847538_11848396_-\|ketopantoate-reductase-family-protein	unknown	unknown	gnl\|CDD\|224805
NZ_CP022098.1\|WP_095991337.1\|11831253_11831640_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319898
NZ_CP022098.1\|WP_095991338.1\|11831846_11832761_-\|subclass-B3-metallo-beta-lactamase	unknown	unknown	gnl\|CDD\|293846
NZ_CP022098.1\|WP_095991348.1\|11844819_11845362_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319898
NZ_CP022098.1\|WP_095991342.1\|11835590_11836253_-\|NAD(P)H-binding-protein	unknown	unknown	gnl\|CDD\|187560
NZ_CP022098.1\|WP_095992662.1\|11837166_11837721_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP022098.1\|WP_095991347.1\|11843717_11844392_-\|HAD-family-phosphatase	unknown	unknown	gnl\|CDD\|223710

Protein	Function_ID	Function_description	E-value
NZ_CP022098.1\|WP_095991349.1\|11845364_11846069_-\|YafY-family-transcriptional-regulator	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	4.91719e-56
NZ_CP022098.1\|WP_095991346.1\|11839966_11841523_-\|TROVE-domain-containing-protein	gnl\|CDD\|368584	pfam05731, TROVE, TROVE domain. This presumed domain is found in TEP1 and Ro60 proteins, that are RNA-binding components of Telomerase, Ro and Vault RNPs. This domain has been named TROVE, (after Telomerase, Ro and Vault). This domain is probably RNA-binding.	0.000105867
NZ_CP022098.1\|WP_095991345.1\|11838464_11839739_+\|tyrosine--tRNA-ligase	gnl\|CDD\|235645	PRK05912, PRK05912, tyrosyl-tRNA synthetase; Validated.	0
NZ_CP022098.1\|WP_095991343.1\|11836249_11837170_-\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|235737	PRK06197, PRK06197, short chain dehydrogenase; Provisional.	4.45023e-86
NZ_CP022098.1\|WP_095991350.1\|11846163_11846565_+\|glyoxalase	gnl\|CDD\|319925	cd07264, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	3.32156e-19
NZ_CP022098.1\|WP_095991354.1\|11850042_11851935_+\|hypothetical-protein	gnl\|CDD\|238020	cd00063, FN3, Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.	8.63863e-14
NZ_CP022098.1\|WP_095991340.1\|11833963_11834851_-\|SDR-family-oxidoreductase	gnl\|CDD\|212492	cd05327, retinol-DH_like_SDR_c_like, retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs. Classical SDR subgroup containing retinol-DHs, LPORs, and related proteins. Retinol is processed by a medium chain alcohol dehydrogenase followed by retinol-DHs. Pchlide reductases act in chlorophyll biosynthesis. There are distinct enzymes that catalyze Pchlide reduction in light or dark conditions. Light-dependent reduction is via an NADP-dependent SDR, LPOR. Proteins in this subfamily share the glycine-rich NAD-binding motif of the classical SDRs, have a partial match to the canonical active site tetrad, but lack the typical active site Ser. This subgroup includes the human proteins: retinol dehydrogenase -12, -13 ,and -14, dehydrogenase/reductase SDR family member (DHRS)-12 , -13 and -X (a DHRS on chromosome X), and WWOX (WW domain-containing oxidoreductase), as well as a Neurospora crassa SDR encoded by the blue light inducible bli-4 gene. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.98019e-92
NZ_CP022098.1\|WP_095991351.1\|11846627_11847515_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	4.32237e-28
NZ_CP022098.1\|WP_095991336.1\|11830812_11831205_+\|hypothetical-protein	gnl\|CDD\|227936	COG5649, COG5649, Uncharacterized conserved protein [Function unknown].	1.64218e-42
NZ_CP022098.1\|WP_095991339.1\|11832944_11833967_-\|hypothetical-protein	gnl\|CDD\|293841	cd16283, RomA-like_MBL-fold, Enterobacter cloacae RomA and related proteins; MBL-fold metallo hydrolase domain. Derepression of the romA-ramA locus results in a multidrug-resistance phenotype. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	2.24319e-68
NZ_CP022098.1\|WP_095991341.1\|11834886_11835594_-\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	8.56139e-15
NZ_CP022098.1\|WP_095991352.1\|11847538_11848396_-\|ketopantoate-reductase-family-protein	gnl\|CDD\|224805	COG1893, ApbA, Ketopantoate reductase [Coenzyme metabolism].	4.89238e-24
NZ_CP022098.1\|WP_095991337.1\|11831253_11831640_-\|VOC-family-protein	gnl\|CDD\|319898	cd06587, VOC, vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). Type I extradiol dioxygenases catalyze the incorporation of both atoms of molecular oxygen into aromatic substrates, which results in the cleavage of aromatic rings. They are key enzymes in the degradation of aromatic compounds. Type I extradiol dioxygenases include class I and class II enzymes. Class I and II enzymes show sequence similarity; the two-domain class II enzymes evolved from a class I enzyme through gene duplication. Glyoxylase I catalyzes the glutathione-dependent inactivation of toxic methylglyoxal, requiring zinc or nickel ions for activity. The antibiotic resistance proteins in this family use a variety of mechanisms to block the function of antibiotics. Bleomycin resistance protein (BLMA) sequesters bleomycin's activity by directly binding to it. Whereas, three types of fosfomycin resistance proteins employ different mechanisms to render fosfomycin inactive by modifying the fosfomycin molecule. Although the proteins in this superfamily are functionally distinct, their structures are similar. The difference among the three dimensional structures of the three types of proteins in this superfamily is interesting from an evolutionary perspective. Both glyoxalase I and BLMA show domain swapping between subunits. However, there is no domain swapping for type 1 extradiol dioxygenases.	4.1981e-07
NZ_CP022098.1\|WP_095991338.1\|11831846_11832761_-\|subclass-B3-metallo-beta-lactamase	gnl\|CDD\|293846	cd16288, BJP-1_FEZ-1-like_MBL-B3, BJP-1, FEZ-1, GOB-1, Mbl1b and related metallo-beta-lactamases, subclass B3; MBL-fold metallo-hydrolase domain. This subgroup of B3 subclass MBLs includes Bradyrhizobium diazoefficiens BJP-1, Fluoribacter gormanii FEZ-1, Elizabethkingia meningoseptica (Chryseobacterium meningosepticum) GOB-1, Caulobacter crescentus Mbl1b. MBLs (class B of the Ambler beta-lactamase classification) are a diverse group of metallo-enzymes that are capable of catalyzing the hydrolysis of a wide range of beta-lactam antibiotics. MBLs have been divided into three subclasses B1, B2 and B3, based on sequence/structural relationships and substrates, with the B1 and B2 MBLs being most closely related to each other. Subclass B3 enzymes are most active with two zinc ions bound in the active site, and have a broad-spectrum substrate profile. These B3 enzymes have a modified Zn2/DCH site (Asp-His-His).	3.79952e-121
NZ_CP022098.1\|WP_095991348.1\|11844819_11845362_+\|VOC-family-protein	gnl\|CDD\|319898	cd06587, VOC, vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). Type I extradiol dioxygenases catalyze the incorporation of both atoms of molecular oxygen into aromatic substrates, which results in the cleavage of aromatic rings. They are key enzymes in the degradation of aromatic compounds. Type I extradiol dioxygenases include class I and class II enzymes. Class I and II enzymes show sequence similarity; the two-domain class II enzymes evolved from a class I enzyme through gene duplication. Glyoxylase I catalyzes the glutathione-dependent inactivation of toxic methylglyoxal, requiring zinc or nickel ions for activity. The antibiotic resistance proteins in this family use a variety of mechanisms to block the function of antibiotics. Bleomycin resistance protein (BLMA) sequesters bleomycin's activity by directly binding to it. Whereas, three types of fosfomycin resistance proteins employ different mechanisms to render fosfomycin inactive by modifying the fosfomycin molecule. Although the proteins in this superfamily are functionally distinct, their structures are similar. The difference among the three dimensional structures of the three types of proteins in this superfamily is interesting from an evolutionary perspective. Both glyoxalase I and BLMA show domain swapping between subunits. However, there is no domain swapping for type 1 extradiol dioxygenases.	2.13146e-16
NZ_CP022098.1\|WP_095991342.1\|11835590_11836253_-\|NAD(P)H-binding-protein	gnl\|CDD\|187560	cd05250, CC3_like_SDR_a, CC3(TIP30)-like, atypical (a) SDRs. Atypical SDRs in this subgroup include CC3 (also known as TIP30) which is implicated in tumor suppression. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine rich NAD(P)-binding motif that resembles the extended SDRs, and have an active site triad of the SDRs (YXXXK and upstream Ser), although the upstream Asn of the usual SDR active site is substituted with Asp. For CC3, the Tyr of the triad is displaced compared to the usual SDRs and the protein is monomeric, both these observations suggest that the usual SDR catalytic activity is not present. NADP appears to serve an important role as a ligand, and may be important in the interaction with other macromolecules. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.95578e-10
NZ_CP022098.1\|WP_095992662.1\|11837166_11837721_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	6.86553e-08
NZ_CP022098.1\|WP_095991347.1\|11843717_11844392_-\|HAD-family-phosphatase	gnl\|CDD\|223710	COG0637, COG0637, Predicted phosphatase/phosphohexomutase [General function prediction only].	2.61858e-52

>NZ_CP022098.1|WP_095991345.1|11838464_11839739_+|tyrosine--tRNA-ligase
MTTPSIASVQPRSAFLRTLTERGFLNQCSDQTALDAALQQGAVPAYIGFDATADSLHVGHLMSIMTLRWLQRTGHKPIVLIGGGTTRIGDPSFRDSSRPMLDDAQIAANMEGIRRVFAKYLTFGDGPTDAVMVNNADWLDELRYIPLLRDVGQHFTVNRMLSFDSVKLRLDREQPMTFLEFNYMILQAFDFVELSRRHGCRLQMGGSDQWGNIVNGIELGRRMEGLDLFGLTTSLLTTASGIKMGKTASGAVWLNADRLSPWDFWQFWRNTEDADVGRFLRLFTELPLEEIARLEALEGAELNEAKKVLANEATRLCHGAEAATEAAETARRTFEEGAFGEGLHSVAVTRADLDAGLRLVELLVEAGLAESKGAARRLIRDSGARVNGTVVADEAALVTAADLDGEGRIRLSAGRKRHALVRCR
>NZ_CP022098.1|WP_095992662.1|11837166_11837721_-|TetR/AcrR-family-transcriptional-regulator
MTDDEAAARRARVLTAARWCFLNFGFAKTAFEDIAKRAGLSRTLLYRLFKDKEDIYRAVFVEWLVSRHPAAKEAASGAGTAYERLLSVCRLMVLEPWAEMVGAPMGAEFLEACQRIDPESEALHRRVALECVAAIVGDEASAKVFLLALDGLLADEPSNEVLEQRTKVLAARFAPQTRKKAVRS
>NZ_CP022098.1|WP_095991343.1|11836249_11837170_-|SDR-family-NAD(P)-dependent-oxidoreductase
MTTKWNPAQIPSQKGRRTIITGGNSGIGWEAAVVLARAGAEVVIAARNDGKAKESVERLRAIVPNADASTARLDLSDPTSIRAFADAQLALAKPIDVLVHNAGVMALPKREVSIDGHELQFATNVLGPYRLTALLLPALLRSKAPRVVTVASGTHKASPVPLTDLDSVNDYRPIRAYAKTKLANILFAKELQRRAGQRLLSLCCHPGAANTNLAGVTSLPMKLASFAIYPLIQSAARGAEPTLMAATLEAPMPGGYFGPTGFMELRGDPAEVKPAPFAEDPAAGRALFAELEHISGMTINFEGATR
>NZ_CP022098.1|WP_095991342.1|11835590_11836253_-|NAD(P)H-binding-protein
MKIVFLGASGMVGAGALREALAAPDVEAVLSVVRAPTGVMHPKLRELVMADLFEVASVEDQLVGYDACIWAIGISSSGLDEDAYARITEELTLSWARTLLRLNPKLSFCYCSAGGAGGPGMWARVRRRVEDTLKSMPFTHSGAVRPGFIRPGPGIRSKTRAYQLGVVLLKPLFLLTPLLVRFMPFLFTTSEILGRAMLRVVQGRADRFILESADINRVGA
>NZ_CP022098.1|WP_095991341.1|11834886_11835594_-|TVP38/TMEM64-family-protein
MSTTTRSLRNVKLGVVGLVLIMLAAAWSFGVFARVGEPRALAQALVEMGAWGYLAFIVAYTVLQPFGVPGSIFIVAAPLIWPWQTAFALSMVGTMSASVVGFSFARFVARDWVSARIPARLRKYDEALERSAFQTVVLLRLILWMPQVLHSFFGVSKVRFWTHFWGSLVGYVPPLLLVSYLGAEMFDASGKMQPAAWPIMAGLLVASLVIAALARAYERRRLSSSSRELRVAQRG
>NZ_CP022098.1|WP_095991340.1|11833963_11834851_-|SDR-family-oxidoreductase
MTQDLVGKVVLITGATDGIGKAAATEFAKRGATLTIVGRSKQKAEQVLAELKAASGNQNIDLLLCDLSRMADVKRAAEEFRARHDRLDVLVNNAGATFKTPTMGPDGFELTFALNHLAYFQLTTALLDLLKKTPGARVVSTSSGMQARGKLDLAKTPTSLEGSGPSAYATSKLANVLFTKELQRRLEGTTAAANCFEPGTVRTQFGGFGSDQGFLLNLVYTLAKPFSSTPEQGADSLIWLATSPEATPLKGEYVSKRRPARPQKQALDAKLAADLWTLSERLCAEAAGRVAGGTA
>NZ_CP022098.1|WP_095991339.1|11832944_11833967_-|hypothetical-protein
MKFHGLRLERVRASRQFDGEVFRNPAGAWSAPAGSVLPMLPEFLFGGAKRRPKAPLPTMRPHETWGRPINSGLRTTWLGHSTVLLEIDGHRILTDPVFGDRASPFSFAGPKRFHPVPAGLAELPTLDVVLLSHDHYDHLCASTIAALASMPTIPIVTSLGVGSHLERLGIAPERIHELDWGEACDVRGLRFTATPCQHFSGRSLGDRNTTLWSSWVIQSERHKIFFSGDTGLSEQFRETGAKYGPFDLVMLEIGAFHPGFEAIHLGPENALKVFEMLGGGTLLPVHWGTFDLALHTWDEPAETLMRLAAEQSLRIVTPGLGQVVEPSQLDGPTPWWRGLK
>NZ_CP022098.1|WP_095991338.1|11831846_11832761_-|subclass-B3-metallo-beta-lactamase
MKPLHLAAASLALVLALPSSAQSAAPTPPAARDWPSNWNTPTEPFRIIDNIYYVGTEGLGSYLFVTPEGHILLDGALPESAPLIEANIQKLGFKLSDIKYLLNSHAHFDHSGGLAQLKKDTGATLIASERDQSALEGGFYLGNEDEGATVPKVKVDRAIQDGYQLKLGGRTFTAHLTPGHSRGCTSWGFEVKDGGKTHPGLVFCSATIAANRLVERPQYEGIVGDYRSTFEKAARLKVDVFLAPHPEFFDLSGKRVKLAAGARPNPFIDPAGYQGFIARLKAAFEVGLKEQQDAAAKAVKAKGP
>NZ_CP022098.1|WP_095991337.1|11831253_11831640_-|VOC-family-protein
MHLGNFSVSLAVKDIAVSRAFYEKLGFRAIGGDQAQNWLIMQNETSTIGLFQGMFDKNILTFNPGWDRNANPLADFDDVRELQQTLQARGITLVSAADESSTGPASLMLIDPDGNPILIDQHVPKPKR
>NZ_CP022098.1|WP_095991336.1|11830812_11831205_+|hypothetical-protein
MSASERIDQKIASLGDWRGERLAEIRKLIHEVDPEVVEDWKWMGTPVWSHDGMYVLANPFKGKVKMTFFHGAQLPDPKKLFNADLKGGKWRAIDLREGDKLDTTALKALLRAAVDYNTTHSVPKSKGSRA
>NZ_CP022098.1|WP_095991346.1|11839966_11841523_-|TROVE-domain-containing-protein
MANLSLFQTTRGPAMPRPDALNEEGAPAFSFTPRHALAQYAATGCLNGTFYAAAEVQLDQLLALSGQVEPEFVARTALYCRHRGYMKDTPALLCAVLSVLGPELLPRVFPRVIDNGRMLRTFVQIMRSGLVARRSLGSLPKRLVREWLDARDEDTLFRDSVGQSPSLADIIRMVHPKPKTARREAFYGYLLGRPHAREALPELVAHYEDFKVRPSSREVPEVPFQLLTSLPLKTAAWVRIAQGASWQMTRMNLNTFARHGVFGESGMEKMIARRLADPAEVRRARVFPYQLLATWRAVGRQVPARVRDAVEEAMEVAIENVPRVDGRAYVCVDVSGSMQSPVTGHREGATTAVRCVDVAALLAAAMLRRNPGTQVVPFDHDVVPLTLHARDSIMTNAQRLAAVGGGGTSCSAPLAWLNARQAKGELVIFVSDNESWVDARAGAGTETLRQWELFRRRNPNARLMCIDLQPYRTTQAPEREDILNVGGFSDVVFELMSDFARGGLDARRWVESIESTGL
>NZ_CP022098.1|WP_095991347.1|11843717_11844392_-|HAD-family-phosphatase
MQPGTSRPYPFDAVLFDLDGVIIDTTALYYRVWETFARARGRVPTPAELLATNGRRGSETLQAWFGPGLAESDIAAHMHELDAMVRHQLATEPVSAVPGVHRFLEELRRAGVPWALGTSATAANAELALSRLGLSELFPVRVTAAEVTRGKPDPEVYLKAAAALGVAPSACVVIEDSVLGLRAGRAAGARCLALSTTFPRDVLSNEDPTWLAEDFRSLPFSVSP
>NZ_CP022098.1|WP_095991348.1|11844819_11845362_+|VOC-family-protein
MTLQARHPSRLHHTAYVTRDLEATRKFYEDLIGLPLVATWCEADELFGAVRTYCHTFFELGDGSALAFFQFEKPSDQELFGPKLPPTPFHHIALNVDRETQDGIEQRLRAAGHSEPGMYVLEHGYCRSLYVQDPNGMLVEFTWDNPEAVTPEATRSRRAQAHGELKRWLAGHRDSNNTFR
>NZ_CP022098.1|WP_095991349.1|11845364_11846069_-|YafY-family-transcriptional-regulator
MRRADRLFQLIQILRRSSRPVTADALAAELEVSKRSIYRDVADLIGQRVPIRGEAGIGYVLERDFDMPPLMLTPDELEAAVLGAQWVAERGDAALASAARDLVAKIAAVVPERLRPFIAEPTIGAPLPLGVAVDGLDMARTRAWIRSGRKIRIRYRDDQGRESERTIWPVIIGYAEAVRLLAAWCELRSTFRHFRTDRILAAEFRDERHGVSPDDLRARWRRHFEAERGVRLPG
>NZ_CP022098.1|WP_095991350.1|11846163_11846565_+|glyoxalase
MNFVSIRLITADLERLVRFYERLSGLRATRYTEDFAELITPACTLAIGSTRTLQLFGGDIARPADNHTAIIEFRVDDVDESFRRLKDVIGGALVQEPTTMPWGNRSLLFRDPDGTLVNFFTPVTKEAIAKFNR
>NZ_CP022098.1|WP_095991351.1|11846627_11847515_+|LysR-family-transcriptional-regulator
METKYEPSWDDLRVLLAVHRHRSFLAAGRALGISTSTTARRIEALEQALDRPLVHRSSAGTSVEPEALELVNLAEQLELGLQSVRRDEGDATASGTVRLSLSDGLIIPVTQVLATLRQKHPALLFEVSSEARMADLSRREADIGIRMARSASPVLVQRLIGRAQLGLYAARSYVERRVRDGRLKRQDMARHDFIGFETSHDKMPQVQWLIEQGAKRFVFRSNSYFAMREAAELGLGIMILGVMQVPPGSELVRLETEGEPPWVSAYLAYHRELRNVKRIRLVLDALESAFRAMRT
>NZ_CP022098.1|WP_095991352.1|11847538_11848396_-|ketopantoate-reductase-family-protein
MPQRIAVLGAGAIGTAFAYQLAQAGHAVTVVARGVRLARLRSDDGIVLVDGRRAAITLATTLPPTEDFDLVLVTVLSPQVPAVLPDLVASAARRVMFMFNTFESIAPLRDAVGADRFTFGFPGGVFSLIKDGRIEHQVRPGTTVIAAEDAALFSAAGIPTVTTPDMHAWLRSHAALVVGLMSVGCRAVATGRGITWAEARTAALATRQAYDLVRDLGHPILPSSLRVASALPRVLWALTFWLGSRAKILRDLGALGPQESRMLIDQMVAAAPPTKALDALRAIRL
>NZ_CP022098.1|WP_095991353.1|11848598_11849411_-|hypothetical-protein
MTISKLLSASDALVADQWQKLQPPGDSTAYRLLKEAGFFIWRTGQLYRFEDYLVRPSADRAVDVRTSWRGENGEEASEAWQTLARIRDTLQSAEKKNLIQVARAQLEFIASTGQCEEFHDYLKTFYRNPPPVIARFDTRDEAETWLRNLPEPPSSAYILVGNEYLEVFYSRERGVRALRRDYALERFIEAVASRGLPAPAASFDTHAEAAAWWKNHPAPPLSVFVRIAGELHFAVFHKKIDYRSLHPISILEDWRREQERIAEQEKTRSR
>NZ_CP022098.1|WP_095992663.1|11849407_11849617_-|hypothetical-protein
MRFEAMDTAVDWVRRHRTKILAGTVIIIAGVAFIAVVGASGGAALVFVPVVLVASSDNPLGFELMPETP
>NZ_CP022098.1|WP_095991354.1|11850042_11851935_+|hypothetical-protein
MFRNLVPVRKLIAGTLAFSLGCGVGPSPGMEEETGSATESTQGLGATERALASDRAYQWLKAQQDLTNGSALSGLVDSFDDWWNTTERKQIVYTYDQAVAAIAFMAKGDRVRAEKVLDKLVAIQDPDGSWINSYWWNGYGEELRKHVGPVAWVTMAFMTHEKLYGSTTYRTPARKALEWMLTFKKPNGAISGGRTTWDIQGVWTDEVWSSTEHNEDVYNLYRYYAGKFSDRTSAYNDAAQGVKQFLDNVMWNDTTKRFYGGWKNNTGLLDTNVPLDVNPWGILALGLSGTRDYKASLASVDNARGVGTVADPRYVHTLPYENTTITAYDFDWQYDCARANDQNGNYNGDRCADIWFEGSAFMSVAHHMNGNTTKADSIIDEIIKKQGTSGSLLGGVPYSLKGTSNNYWRMAQENCVSSTGWLILAIHRFNPFTGSVVNGGTNPTDTQAPSTPSSLKVSSTTSSSVTLSWTASTDNVGVAGYDIYRGSTLVGSSSATTFTVSGLSASTTYSFSIKARDAAGNTSAASNTVSATTSAAGNDGGHTTADYTANVTRTSSTQARISFKPTTSALYVDVHYTLNGGGQQNLRMALANGTWTQDVAGLSTGSRLEYWFTYEKSGPQYDSPHYTYTH

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP022098_8	8.5\|2249360\|16\|NZ_CP022098\|CRISPRCasFinder	2249360-2249375	16	NZ_CP022098.1	7000190-7000205	0	1.0
NZ_CP022098_12	12.2\|3423376\|19\|NZ_CP022098\|CRISPRCasFinder	3423376-3423394	19	NZ_CP022098.1	3423409-3423427	0	1.0
NZ_CP022098_15	15.1\|5454197\|22\|NZ_CP022098\|CRT	5454197-5454218	22	NZ_CP022098.1	5454098-5454119	0	1.0
NZ_CP022098_11	11.1\|3030338\|18\|NZ_CP022098\|CRISPRCasFinder	3030338-3030355	18	NZ_CP022098.1	4340303-4340320	1	0.944
NZ_CP022098_11	11.2\|3030380\|18\|NZ_CP022098\|CRISPRCasFinder	3030380-3030397	18	NZ_CP022098.1	10190040-10190057	1	0.944
NZ_CP022098_12	12.1\|3423334\|19\|NZ_CP022098\|CRISPRCasFinder	3423334-3423352	19	NZ_CP022098.1	8958501-8958519	1	0.947
NZ_CP022098_12	12.2\|3423376\|19\|NZ_CP022098\|CRISPRCasFinder	3423376-3423394	19	NZ_CP022098.1	3557978-3557996	1	0.947
NZ_CP022098_15	15.2\|5454245\|19\|NZ_CP022098\|CRT	5454245-5454263	19	NZ_CP022098.1	10716500-10716518	1	0.947
NZ_CP022098_15	15.3\|5454290\|22\|NZ_CP022098\|CRT	5454290-5454311	22	NZ_CP022098.1	5454050-5454071	1	0.955
NZ_CP022098_19	19.1\|9631752\|18\|NZ_CP022098\|CRISPRCasFinder	9631752-9631769	18	NZ_CP022098.1	4340303-4340320	1	0.944
NZ_CP022098_19	19.2\|9631794\|18\|NZ_CP022098\|CRISPRCasFinder	9631794-9631811	18	NZ_CP022098.1	10190040-10190057	1	0.944

1. spacer 8.5|2249360|16|NZ_CP022098|CRISPRCasFinder matches to position: 7000190-7000205, mismatch: 0, identity: 1.0

ttctcctgctgccgct	CRISPR spacer
ttctcctgctgccgct	Protospacer
****************

2. spacer 12.2|3423376|19|NZ_CP022098|CRISPRCasFinder matches to position: 3423409-3423427, mismatch: 0, identity: 1.0

aggaggaggcggaagcggc	CRISPR spacer
aggaggaggcggaagcggc	Protospacer
*******************

3. spacer 15.1|5454197|22|NZ_CP022098|CRT matches to position: 5454098-5454119, mismatch: 0, identity: 1.0

tggtcctccgggaccgggcgct	CRISPR spacer
tggtcctccgggaccgggcgct	Protospacer
**********************

4. spacer 11.1|3030338|18|NZ_CP022098|CRISPRCasFinder matches to position: 4340303-4340320, mismatch: 1, identity: 0.944

cgggtgagcgccttcacc	CRISPR spacer
cgggtgcgcgccttcacc	Protospacer
****** ***********

5. spacer 11.2|3030380|18|NZ_CP022098|CRISPRCasFinder matches to position: 10190040-10190057, mismatch: 1, identity: 0.944

gcatcccgcgcggccacc	CRISPR spacer
gcatgccgcgcggccacc	Protospacer
**** *************

6. spacer 12.1|3423334|19|NZ_CP022098|CRISPRCasFinder matches to position: 8958501-8958519, mismatch: 1, identity: 0.947

agcgcctggcgctcgagga	CRISPR spacer
agcgccgggcgctcgagga	Protospacer
****** ************

7. spacer 12.2|3423376|19|NZ_CP022098|CRISPRCasFinder matches to position: 3557978-3557996, mismatch: 1, identity: 0.947

aggaggaggcggaagcggc	CRISPR spacer
aggaggaggcggaggcggc	Protospacer
*************.*****

8. spacer 15.2|5454245|19|NZ_CP022098|CRT matches to position: 10716500-10716518, mismatch: 1, identity: 0.947

tatgccgggccctggggcg	CRISPR spacer
tacgccgggccctggggcg	Protospacer
**.****************

9. spacer 15.3|5454290|22|NZ_CP022098|CRT matches to position: 5454050-5454071, mismatch: 1, identity: 0.955

cggtcctccgggaccgggcgct	CRISPR spacer
cggtccgccgggaccgggcgct	Protospacer
****** ***************

10. spacer 19.1|9631752|18|NZ_CP022098|CRISPRCasFinder matches to position: 4340303-4340320, mismatch: 1, identity: 0.944

cgggtgagcgccttcacc	CRISPR spacer
cgggtgcgcgccttcacc	Protospacer
****** ***********

11. spacer 19.2|9631794|18|NZ_CP022098|CRISPRCasFinder matches to position: 10190040-10190057, mismatch: 1, identity: 0.944

gcatcccgcgcggccacc	CRISPR spacer
gcatgccgcgcggccacc	Protospacer
**** *************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP022098_15	15.1\|5454197\|22\|NZ_CP022098\|CRT	5454197-5454218	22	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	275728-275749	2	0.909
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP015867	Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence	100707-100735	3	0.897
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	413933-413963	4	0.871
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	1509608-1509636	5	0.828
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	224753-224781	5	0.828
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP029832	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence	240447-240475	5	0.828
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	303655-303683	5	0.828
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	248034-248062	5	0.828
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP015744	Shinella sp. HZN7 plasmid pShin-08, complete sequence	116329-116357	5	0.828
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP028348	Novosphingobium sp. THN1 plasmid pTHN, complete sequence	379496-379524	5	0.828
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NZ_CP024309	Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3b, complete sequence	9632-9662	6	0.806
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NZ_CP042824	Rhizobium sp. WL3 plasmid unnamed1, complete sequence	15393-15423	6	0.806
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	LR606149	Rhizobium sp. Q54 genome assembly, plasmid: 6	73525-73555	6	0.806
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NZ_CP006988	Rhizobium sp. IE4771 plasmid pRetIE4771b, complete sequence	11110-11140	6	0.806
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NZ_CP054030	Rhizobium sp. JKLM19E plasmid pPR19E03	65869-65899	6	0.806
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NZ_CP032923	Agrobacterium tumefaciens strain 1D1108 plasmid pAt1D1108a, complete sequence	28618-28648	6	0.806
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NZ_CP032924	Agrobacterium tumefaciens strain 1D1108 plasmid pAt1D1108b, complete sequence	17316-17346	6	0.806
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	113592-113620	6	0.793
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_LN831788	Streptomyces leeuwenhoekii strain type strain (C34 = DSM 42122 = NRRL B-24963) plasmid pSLE1, complete sequence	40307-40335	6	0.793
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2655986-2656014	6	0.793
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5313075-5313103	6	0.793
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	3008001-3008029	6	0.793
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	1699528-1699556	6	0.793
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	MT711975	Streptomyces phage Alderaan, complete genome	3065-3093	6	0.793
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_LR134446	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 4, complete sequence	58232-58260	6	0.793
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	MN103533	Mycobacterium phage Weirdo19, complete genome	23994-24022	6	0.793
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	CP054924	Verrucosispora sp. NA02020 plasmid unnamed, complete sequence	9404-9432	6	0.793
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP030863	Streptomyces globosus strain LZH-48 plasmid unnamed1, complete sequence	62771-62799	6	0.793
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP018081	Sulfitobacter sp. AM1-D1 plasmid unnamed5, complete sequence	274004-274032	6	0.793
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP045388	Ruegeria sp. THAF33 plasmid pTHAF33_d, complete sequence	67306-67334	6	0.793
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	MN602278	Escherichia coli plasmid pUZ8002, complete sequence	6549-6577	6	0.793
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	JX469830	Uncultured bacterium plasmid pG527, complete sequence	48044-48072	6	0.793
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	JX469833	Uncultured bacterium plasmid pWEC911, complete sequence	41336-41364	6	0.793
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NC_008357	Pseudomonas aeruginosa plasmid pBS228, complete sequence	74298-74326	6	0.793
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	CP002151	Uncultured bacterium plasmid PB5, complete sequence	32552-32580	6	0.793
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	CP002152	Uncultured bacterium plasmid PB11, complete sequence	35035-35063	6	0.793
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	CP002153	Uncultured bacterium plasmid PSP21, complete sequence	36723-36751	6	0.793
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP045387	Ruegeria sp. THAF33 plasmid pTHAF33_c, complete sequence	36531-36559	6	0.793
NZ_CP022098_17	17.2\|6605255\|30\|NZ_CP022098\|CRISPRCasFinder	6605255-6605284	30	NZ_CP021084	Deinococcus ficus strain CC-FR2-10 plasmid pDFI3, complete sequence	63132-63161	6	0.8
NZ_CP022098_17	17.2\|6605255\|30\|NZ_CP022098\|CRISPRCasFinder	6605255-6605284	30	NC_042088	Gordonia phage Gustav, complete genome	26458-26487	6	0.8
NZ_CP022098_17	17.2\|6605255\|30\|NZ_CP022098\|CRISPRCasFinder	6605255-6605284	30	MH271305	Gordonia phage Morrissey, complete genome	26823-26852	6	0.8
NZ_CP022098_1	1.1\|43665\|31\|NZ_CP022098\|CRISPRCasFinder	43665-43695	31	NZ_CP021914	Sagittula sp. P11 plasmid unnamed1, complete sequence	73371-73401	7	0.774
NZ_CP022098_1	1.1\|43665\|31\|NZ_CP022098\|CRISPRCasFinder	43665-43695	31	MT553342	Microbacterium phage Kelcole, complete genome	18492-18522	7	0.774
NZ_CP022098_1	1.1\|43665\|31\|NZ_CP022098\|CRISPRCasFinder	43665-43695	31	MT310894	Microbacterium phage Tempo, complete genome	18519-18549	7	0.774
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NZ_CP025013	Rhizobium leguminosarum strain Norway plasmid pRLN1, complete sequence	415587-415617	7	0.774
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NZ_CP006987	Rhizobium sp. IE4771 plasmid pRetIE4771a, complete sequence	5187-5217	7	0.774
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NZ_CP025507	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvA, complete sequence	431155-431185	7	0.774
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NC_011368	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence	576648-576678	7	0.774
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NZ_CP022670	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR5, complete sequence	70722-70752	7	0.774
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP012477	Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence	481150-481178	7	0.759
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP026489	Streptomyces sp. 604F plasmid unnamed, complete sequence	15452-15480	7	0.759
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	881609-881637	7	0.759
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	291592-291620	7	0.759
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	208535-208563	7	0.759
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_AP019795	Thermus thermophilus strain AA2-29 plasmid pAA229, complete sequence	40946-40974	7	0.759
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_AP019793	Thermus thermophilus strain AA2-20 plasmid pAA220, complete sequence	66133-66161	7	0.759
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	1136506-1136534	7	0.759
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP009154	Burkholderia pseudomallei strain TSV202 plasmid 2, complete sequence	39142-39170	7	0.759
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP054608	Sulfitobacter pseudonitzschiae strain H46 plasmid unnamed9, complete sequence	44226-44254	7	0.759
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP032313	Pannonibacter phragmitetus BB plasmid p.BB_1, complete sequence	49379-49407	7	0.759
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP045120	Rubrobacter sp. SCSIO 52909 plasmid unnamed1, complete sequence	129892-129920	7	0.759
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP023455	Rhodobacteraceae bacterium QY30 plasmid unnamed, complete sequence	31142-31170	7	0.759
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP045391	Roseivivax sp. THAF30 plasmid pTHAF30_b, complete sequence	63860-63888	7	0.759
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP045363	Roseivivax sp. THAF40 plasmid pTHAF40_c, complete sequence	31287-31315	7	0.759
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	LN997843	Streptomyces reticuli genome assembly TUE45, plasmid : II	630912-630940	7	0.759
NZ_CP022098_14	14.2\|4993035\|29\|NZ_CP022098\|CRISPRCasFinder	4993035-4993063	29	NZ_LR699074	Beijerinckiaceae bacterium RH AL1 isolate RH_AL1 plasmid 2	9436-9464	7	0.759
NZ_CP022098_17	17.2\|6605255\|30\|NZ_CP022098\|CRISPRCasFinder	6605255-6605284	30	NZ_LR594673	Variovorax sp. PBL-E5 plasmid 3	524423-524452	7	0.767
NZ_CP022098_1	1.1\|43665\|31\|NZ_CP022098\|CRISPRCasFinder	43665-43695	31	NZ_CP015740	Shinella sp. HZN7 plasmid pShin-04, complete sequence	215455-215485	8	0.742
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NZ_CP026529	Sinorhizobium meliloti strain AK21 plasmid pSmeAK21b, complete sequence	10572-10602	8	0.742
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NZ_CP033509	Mesorhizobium jarvisii strain ATCC 700743 plasmid pMJ700743b, complete sequence	13098-13128	8	0.742
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NZ_CP033370	Mesorhizobium loti strain SU343 plasmid pMLSU343b, complete sequence	19435-19465	8	0.742
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NC_011879	Pseudarthrobacter chlorophenolicus A6 plasmid pACHL01, complete sequence	162194-162222	8	0.724
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	533480-533508	8	0.724
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP041744	Paraburkholderia megapolitana strain LMG 23650 plasmid unnamed1, complete sequence	120601-120629	8	0.724
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NC_016585	Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence	506440-506468	8	0.724
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP029830	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence	296594-296622	8	0.724
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	1598887-1598915	8	0.724
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP045407	Roseovarius sp. THAF9 plasmid pTHAF9_c, complete sequence	51837-51865	8	0.724
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP034813	Paracoccus sp. Arc7-R13 plasmid unnamed2, complete sequence	136900-136928	8	0.724
NZ_CP022098_14	14.1\|4992981\|29\|NZ_CP022098\|CRISPRCasFinder	4992981-4993009	29	NZ_CP054032	Rhizobium sp. JKLM13E plasmid pPR13E01, complete sequence	173193-173221	8	0.724
NZ_CP022098_22	22.1\|11610280\|31\|NZ_CP022098\|CRISPRCasFinder	11610280-11610310	31	MN693926	Marine virus AFVG_250M186, complete genome	15631-15661	8	0.742
NZ_CP022098_1	1.1\|43665\|31\|NZ_CP022098\|CRISPRCasFinder	43665-43695	31	NZ_CP031793	Klebsiella pneumoniae strain INF116-sc-2279924 plasmid unnamed1, complete sequence	82410-82440	9	0.71
NZ_CP022098_1	1.1\|43665\|31\|NZ_CP022098\|CRISPRCasFinder	43665-43695	31	NZ_CP021946	Klebsiella pneumoniae strain AR_0152 plasmid tig00000195, complete sequence	52743-52773	9	0.71
NZ_CP022098_1	1.1\|43665\|31\|NZ_CP022098\|CRISPRCasFinder	43665-43695	31	NZ_CP013986	Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence	133347-133377	9	0.71
NZ_CP022098_1	1.1\|43665\|31\|NZ_CP022098\|CRISPRCasFinder	43665-43695	31	NZ_CP045691	Klebsiella pneumoniae strain TK421 plasmid pTK421_1, complete sequence	121961-121991	9	0.71
NZ_CP022098_1	1.1\|43665\|31\|NZ_CP022098\|CRISPRCasFinder	43665-43695	31	NZ_CP032357	Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence	103844-103874	9	0.71
NZ_CP022098_1	1.1\|43665\|31\|NZ_CP022098\|CRISPRCasFinder	43665-43695	31	NZ_CP011518	Pandoraea oxalativorans strain DSM 23570 plasmid pPO70-1, complete sequence	215412-215442	9	0.71
NZ_CP022098_1	1.1\|43665\|31\|NZ_CP022098\|CRISPRCasFinder	43665-43695	31	NZ_CP032342	Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence	181825-181855	9	0.71
NZ_CP022098_1	1.1\|43665\|31\|NZ_CP022098\|CRISPRCasFinder	43665-43695	31	NZ_CP033321	Azospirillum brasilense strain Cd plasmid p3, complete sequence	615714-615744	9	0.71
NZ_CP022098_1	1.1\|43665\|31\|NZ_CP022098\|CRISPRCasFinder	43665-43695	31	NZ_CP033315	Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence	21802-21832	9	0.71
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	LR606148	Rhizobium sp. Q54 genome assembly, plasmid: 5	8445-8475	9	0.71
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NZ_CP039693	Agrobacterium larrymoorei strain CFBP5473 plasmid pAlCFBP5473, complete sequence	41779-41809	9	0.71
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NZ_CP039913	Agrobacterium tumefaciens strain CFBP6625 plasmid pAtCFBP6625b, complete sequence	29090-29120	9	0.71
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NZ_LR723672	Rhizobium flavum strain YW14 plasmid 3	31133-31163	9	0.71
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	CP047390	Agrobacterium sp. CGMCC 11546 plasmid pB	31554-31584	9	0.71
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NC_021909	Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1e, complete sequence	605420-605450	9	0.71
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NZ_CP021815	Sinorhizobium meliloti strain M270 plasmid accessoryA, complete sequence	263613-263643	9	0.71
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NZ_CP016451	Sinorhizobium sp. RAC02 plasmid pBSY16_2, complete sequence	35962-35992	9	0.71
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NC_011982	Agrobacterium vitis S4 plasmid pTiS4, complete sequence	30346-30376	10	0.677
NZ_CP022098_7	7.1\|1890314\|31\|NZ_CP022098\|CRISPRCasFinder	1890314-1890344	31	NZ_CP034999	Rhizobium acidisoli strain FH23 plasmid pRapFH23a, complete sequence	250082-250112	10	0.677
NZ_CP022098_17	17.1\|6605195\|33\|NZ_CP022098\|CRISPRCasFinder	6605195-6605227	33	NZ_CP029830	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence	682620-682652	10	0.697

1. spacer 15.1|5454197|22|NZ_CP022098|CRT matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 2, identity: 0.909

tggtcctccgggaccgggcgct	CRISPR spacer
tggtcctccgggtccgggcgcc	Protospacer
************ ********.

2. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP015867 (Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence) position: , mismatch: 3, identity: 0.897

ggtga-cggcggccccgatggcctcggccg	CRISPR spacer
-gtgaccggcggcgccgaaggcctcggccg	Protospacer
 **** ******* **** ***********

3. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 4, identity: 0.871

gccgggatggtgtccgccgggatggt-gtcgc	CRISPR spacer
gccggggtggtgtccgccggaatggtcatcg-	Protospacer
******.*************.***** .***

4. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 5, identity: 0.828

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
gttgtcggcggccccgacggcctcggcgt	Protospacer
* ** ************.*********

5. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 5, identity: 0.828

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
gttgacggcggcctcgatgtcctcgtcgg	Protospacer
* ***********.***** ***** * *

6. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP029832 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.828

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
ggtgacggcggcgccgatcgcctcgcagg	Protospacer
************ ***** ******   *

7. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 5, identity: 0.828

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
gttgtcggcggccccgacggcctcggcgt	Protospacer
* ** ************.*********

8. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 5, identity: 0.828

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
gaagccggcggcctcgatggcctcggcca	Protospacer
*. * ********.**************.

9. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP015744 (Shinella sp. HZN7 plasmid pShin-08, complete sequence) position: , mismatch: 5, identity: 0.828

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
gccgtcggcggccacgatggcctcggcgg	Protospacer
* .* ******** ************* *

10. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP028348 (Novosphingobium sp. THN1 plasmid pTHN, complete sequence) position: , mismatch: 5, identity: 0.828

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
ggcaagggcggcgccgatggcctcgaccg	Protospacer
**..* ****** ************.***

11. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP024309 (Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3b, complete sequence) position: , mismatch: 6, identity: 0.806

--gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
aagcc--gctggtgtcggccgggatggtgtcca	Protospacer
  ***  * ******* **************

12. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP042824 (Rhizobium sp. WL3 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.806

--gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
aagcc--gctggtgtccgccggcatggtggcga	Protospacer
  ***  * ************* ****** **

13. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to LR606149 (Rhizobium sp. Q54 genome assembly, plasmid: 6) position: , mismatch: 6, identity: 0.806

--gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
aagcc--gctggtgtcggccgggatggtggcga	Protospacer
  ***  * ******* ************ **

14. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP006988 (Rhizobium sp. IE4771 plasmid pRetIE4771b, complete sequence) position: , mismatch: 6, identity: 0.806

--gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
aggcc--gctggtgtcggccgggatggtggcga	Protospacer
  ***  * ******* ************ **

15. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP054030 (Rhizobium sp. JKLM19E plasmid pPR19E03) position: , mismatch: 6, identity: 0.806

--gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
aagcc--gttggtgtcggccgggatggtggcga	Protospacer
  ***  * ******* ************ **

16. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP032923 (Agrobacterium tumefaciens strain 1D1108 plasmid pAt1D1108a, complete sequence) position: , mismatch: 6, identity: 0.806

--gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
aagcc--gctggtgtcggccgggatggtggcga	Protospacer
  ***  * ******* ************ **

17. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP032924 (Agrobacterium tumefaciens strain 1D1108 plasmid pAt1D1108b, complete sequence) position: , mismatch: 6, identity: 0.806

--gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
aagcc--gttggtgtcggccgggatggtggcga	Protospacer
  ***  * ******* ************ **

18. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 6, identity: 0.793

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
gaccacgtcggccccgctggcctcggcct	Protospacer
*.. *** ******** ***********

19. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_LN831788 (Streptomyces leeuwenhoekii strain type strain (C34 = DSM 42122 = NRRL B-24963) plasmid pSLE1, complete sequence) position: , mismatch: 6, identity: 0.793

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
ggtgacggcggccccgatgacatcgctga	Protospacer
*******************.* *** . .

20. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.793

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
gaacacggcggcctcgatggcctcgacca	Protospacer
*.  *********.***********.**.

21. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.793

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
ctcgacggcggcccgggtggcctcggcgg	Protospacer
  .*********** *.********** *

22. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.793

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
gacggcgccggcctcgatggcctcggcca	Protospacer
*..*.** *****.**************.

23. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 6, identity: 0.793

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
gaccacgtcggccccgctggcctcggcct	Protospacer
*.. *** ******** ***********

24. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to MT711975 (Streptomyces phage Alderaan, complete genome) position: , mismatch: 6, identity: 0.793

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
gtcgacggcggcctcgatgtcctcggcgt	Protospacer
* .**********.***** *******

25. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_LR134446 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 4, complete sequence) position: , mismatch: 6, identity: 0.793

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
cgcgacggcggcgccgacggcctcggcga	Protospacer
 *.********* ****.********* .

26. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to MN103533 (Mycobacterium phage Weirdo19, complete genome) position: , mismatch: 6, identity: 0.793

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
cgccgcggcgaccccgatcgcctcggccg	Protospacer
 *. .*****.******* **********

27. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to CP054924 (Verrucosispora sp. NA02020 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
ggtgacggcgtcccagatggcctggacgt	Protospacer
********** *** ******** *.*

28. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP030863 (Streptomyces globosus strain LZH-48 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.793

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
gatgacggcggccgcgatggcctggctca	Protospacer
*.*********** ********* * .*.

29. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP018081 (Sulfitobacter sp. AM1-D1 plasmid unnamed5, complete sequence) position: , mismatch: 6, identity: 0.793

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
ggcggaggcgtccccgatggcctcggcga	Protospacer
**.*. **** **************** .

30. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP045388 (Ruegeria sp. THAF33 plasmid pTHAF33_d, complete sequence) position: , mismatch: 6, identity: 0.793

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
ggcggaggcgtccccgatggcctcggcga	Protospacer
**.*. **** **************** .

31. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to MN602278 (Escherichia coli plasmid pUZ8002, complete sequence) position: , mismatch: 6, identity: 0.793

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
gctcacggcggccgcgatgccctcggcgt	Protospacer
* * ********* ***** *******

32. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to JX469830 (Uncultured bacterium plasmid pG527, complete sequence) position: , mismatch: 6, identity: 0.793

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
gctcacggcggccgcgatgccctcggcgt	Protospacer
* * ********* ***** *******

33. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to JX469833 (Uncultured bacterium plasmid pWEC911, complete sequence) position: , mismatch: 6, identity: 0.793

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
gctcacggcggccgcgatgccctcggcgt	Protospacer
* * ********* ***** *******

34. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NC_008357 (Pseudomonas aeruginosa plasmid pBS228, complete sequence) position: , mismatch: 6, identity: 0.793

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
gctcacggcggccgcgatgccctcggcgt	Protospacer
* * ********* ***** *******

35. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to CP002151 (Uncultured bacterium plasmid PB5, complete sequence) position: , mismatch: 6, identity: 0.793

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
gctcacggcggccgcgatgccctcggcgt	Protospacer
* * ********* ***** *******

36. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to CP002152 (Uncultured bacterium plasmid PB11, complete sequence) position: , mismatch: 6, identity: 0.793

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
gctcacggcggccgcgatgccctcggcgt	Protospacer
* * ********* ***** *******

37. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to CP002153 (Uncultured bacterium plasmid PSP21, complete sequence) position: , mismatch: 6, identity: 0.793

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
gctcacggcggccgcgatgccctcggcgt	Protospacer
* * ********* ***** *******

38. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP045387 (Ruegeria sp. THAF33 plasmid pTHAF33_c, complete sequence) position: , mismatch: 6, identity: 0.793

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
ggcggaggcgtccccgatggcctcggcga	Protospacer
**.*. **** **************** .

39. spacer 17.2|6605255|30|NZ_CP022098|CRISPRCasFinder matches to NZ_CP021084 (Deinococcus ficus strain CC-FR2-10 plasmid pDFI3, complete sequence) position: , mismatch: 6, identity: 0.8

cggaggtgaccctccggggccgcgcggcgg	CRISPR spacer
tgggtgtgaccctcctgggccgcgtggcga	Protospacer
.**. ********** ********.****.

40. spacer 17.2|6605255|30|NZ_CP022098|CRISPRCasFinder matches to NC_042088 (Gordonia phage Gustav, complete genome) position: , mismatch: 6, identity: 0.8

cggaggtgaccctccggggccgcgcggcgg	CRISPR spacer
cggagttgaccctccgaggccgcttggttg	Protospacer
***** **********.****** .**. *

41. spacer 17.2|6605255|30|NZ_CP022098|CRISPRCasFinder matches to MH271305 (Gordonia phage Morrissey, complete genome) position: , mismatch: 6, identity: 0.8

cggaggtgaccctccggggccgcgcggcgg	CRISPR spacer
cggagttgaccctccgaggccgcttggttg	Protospacer
***** **********.****** .**. *

42. spacer 1.1|43665|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP021914 (Sagittula sp. P11 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.774

gttggccgtgggggcgggcgcgttgccgagg	CRISPR spacer
ctgcgcgatggcggcgggcgcgatgccgagg	Protospacer
 *  ** .*** ********** ********

43. spacer 1.1|43665|31|NZ_CP022098|CRISPRCasFinder matches to MT553342 (Microbacterium phage Kelcole, complete genome) position: , mismatch: 7, identity: 0.774

gttggccgtgggggcgggcgcgttgccgagg	CRISPR spacer
gatcgccgtggggacgggcgagttgcccgcg	Protospacer
* * *********.****** ****** . *

44. spacer 1.1|43665|31|NZ_CP022098|CRISPRCasFinder matches to MT310894 (Microbacterium phage Tempo, complete genome) position: , mismatch: 7, identity: 0.774

gttggccgtgggggcgggcgcgttgccgagg	CRISPR spacer
gatcgccgtggggacgggcgagttgcccgcg	Protospacer
* * *********.****** ****** . *

45. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP025013 (Rhizobium leguminosarum strain Norway plasmid pRLN1, complete sequence) position: , mismatch: 7, identity: 0.774

--gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
aagcc--attggtgtcggccgggatggtggcga	Protospacer
  ***  . ******* ************ **

46. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP006987 (Rhizobium sp. IE4771 plasmid pRetIE4771a, complete sequence) position: , mismatch: 7, identity: 0.774

--gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
aagcc--attggtgtcggccgggatggtggcga	Protospacer
  ***  . ******* ************ **

47. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP025507 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvA, complete sequence) position: , mismatch: 7, identity: 0.774

--gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
aagcc--attggtgtcggccgggatggtggcga	Protospacer
  ***  . ******* ************ **

48. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NC_011368 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence) position: , mismatch: 7, identity: 0.774

gccgg--gatggtgtccgccgggatggtgtcgc	CRISPR spacer
--cgaccgctggtgtcggccgggatggtggcga	Protospacer
  **.  * ******* ************ **

49. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP022670 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR5, complete sequence) position: , mismatch: 7, identity: 0.774

--gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
aagcc--attggtgtcggccgggatggtggcga	Protospacer
  ***  . ******* ************ **

50. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP012477 (Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.759

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
catgacggcggccccgatggcttcgagtc	Protospacer
 .*******************.***. .

51. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP026489 (Streptomyces sp. 604F plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
ctctacggcggccccgacggcctcggctc	Protospacer
  . *************.*********.

52. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 7, identity: 0.759

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
ctcggcggcggcggcgatggcctcggccc	Protospacer
  .*.*******  **************

53. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.759

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
cacctcggtcgccccgatggcctcggccg	Protospacer
 ..  ***. *******************

54. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.759

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
cccgccggcggcggcgatggcctcggcca	Protospacer
  .* *******  **************.

55. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_AP019795 (Thermus thermophilus strain AA2-29 plasmid pAA229, complete sequence) position: , mismatch: 7, identity: 0.759

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
ggccacggcgaccccgatggcctcgcgga	Protospacer
**. ******.**************   .

56. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_AP019793 (Thermus thermophilus strain AA2-20 plasmid pAA220, complete sequence) position: , mismatch: 7, identity: 0.759

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
ggccacggcgaccccgatggcctcgcgga	Protospacer
**. ******.**************   .

57. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_AP014579 (Burkholderia sp. RPE67 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.759

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
aacgtcgccggcctcgatggcctcggcca	Protospacer
...* ** *****.**************.

58. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP009154 (Burkholderia pseudomallei strain TSV202 plasmid 2, complete sequence) position: , mismatch: 7, identity: 0.759

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
gcgttcctcggcctcgatggcctcggccg	Protospacer
*    *  *****.***************

59. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP054608 (Sulfitobacter pseudonitzschiae strain H46 plasmid unnamed9, complete sequence) position: , mismatch: 7, identity: 0.759

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
tttgacggcggcccagctggcctcgacga	Protospacer
  ************ * ********.* .

60. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP032313 (Pannonibacter phragmitetus BB plasmid p.BB_1, complete sequence) position: , mismatch: 7, identity: 0.759

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
gtcatcggcggcctcgatggcctcgtcca	Protospacer
* .. ********.*********** **.

61. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP045120 (Rubrobacter sp. SCSIO 52909 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.759

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
cggcacggcggccccgacggcctcgacga	Protospacer
 *  *************.*******.* .

62. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP023455 (Rhodobacteraceae bacterium QY30 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
cgatttggcggccctgctggcctcggccg	Protospacer
 *   .********.* ************

63. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP045391 (Roseivivax sp. THAF30 plasmid pTHAF30_b, complete sequence) position: , mismatch: 7, identity: 0.759

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
ggcagaggcgtccccgatggcctcggcga	Protospacer
**... **** **************** .

64. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP045363 (Roseivivax sp. THAF40 plasmid pTHAF40_c, complete sequence) position: , mismatch: 7, identity: 0.759

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
ggcagaggcgtccccgatggcctcggcga	Protospacer
**... **** **************** .

65. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to LN997843 (Streptomyces reticuli genome assembly TUE45, plasmid : II) position: , mismatch: 7, identity: 0.759

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
ggtgacggcggcccggatgccctggagga	Protospacer
************** **** *** *.  .

66. spacer 14.2|4993035|29|NZ_CP022098|CRISPRCasFinder matches to NZ_LR699074 (Beijerinckiaceae bacterium RH AL1 isolate RH_AL1 plasmid 2) position: , mismatch: 7, identity: 0.759

tgccgagaccgtgccggagcaggtgtcca	CRISPR spacer
cgccgagaccgtgccgccgcaggtaatcg	Protospacer
.***************  ******. .*.

67. spacer 17.2|6605255|30|NZ_CP022098|CRISPRCasFinder matches to NZ_LR594673 (Variovorax sp. PBL-E5 plasmid 3) position: , mismatch: 7, identity: 0.767

-----cggaggtgaccctccggggccgcgcggcgg	CRISPR spacer
acctgcg-----gaccctcccgggccgctcggcgg	Protospacer
     **     ******** ******* ******

68. spacer 1.1|43665|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP015740 (Shinella sp. HZN7 plasmid pShin-04, complete sequence) position: , mismatch: 8, identity: 0.742

gttggccgtgggggcgggcgcgttgccgagg	CRISPR spacer
catcgccgtggcggcgggcgcgttgcgccgc	Protospacer
  * ******* **************   *

69. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP026529 (Sinorhizobium meliloti strain AK21 plasmid pSmeAK21b, complete sequence) position: , mismatch: 8, identity: 0.742

gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
aaaccgatggtgtcggccgggatggtggcga	Protospacer
.    ********* ************ **

70. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP033509 (Mesorhizobium jarvisii strain ATCC 700743 plasmid pMJ700743b, complete sequence) position: , mismatch: 8, identity: 0.742

gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
ccgataatggtgtccgccgggatactgtcga	Protospacer
 * . .*****************. *****

71. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP033370 (Mesorhizobium loti strain SU343 plasmid pMLSU343b, complete sequence) position: , mismatch: 8, identity: 0.742

gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
ccgataatggtgtccgccgggatactgtcga	Protospacer
 * . .*****************. *****

72. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NC_011879 (Pseudarthrobacter chlorophenolicus A6 plasmid pACHL01, complete sequence) position: , mismatch: 8, identity: 0.724

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
cagcacggcggccgcgatggccacggcga	Protospacer
 .  ********* ******** **** .

73. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 8, identity: 0.724

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
ggtgccggcggcctcgatggccttcaggt	Protospacer
**** ********.*********. .

74. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP041744 (Paraburkholderia megapolitana strain LMG 23650 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.724

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
cgcgaaggcggccccgatggcctcatgga	Protospacer
 *.** ******************.   .

75. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NC_016585 (Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence) position: , mismatch: 8, identity: 0.724

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
ggtgccggcggcctcgatggccttcaggt	Protospacer
**** ********.*********. .

76. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP029830 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.724

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
ggtgccggcggcctcgatggccttcaggt	Protospacer
**** ********.*********. .

77. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.724

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
ggtgccggcggcctcgatggccttcaggt	Protospacer
**** ********.*********. .

78. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP045407 (Roseovarius sp. THAF9 plasmid pTHAF9_c, complete sequence) position: , mismatch: 8, identity: 0.724

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
agccgaggcgtccccgatggcctcggcga	Protospacer
.*. . **** **************** .

79. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP034813 (Paracoccus sp. Arc7-R13 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.724

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
ggtgccggcggcctcgatggccttcaggt	Protospacer
**** ********.*********. .

80. spacer 14.1|4992981|29|NZ_CP022098|CRISPRCasFinder matches to NZ_CP054032 (Rhizobium sp. JKLM13E plasmid pPR13E01, complete sequence) position: , mismatch: 8, identity: 0.724

ggtgacggcggccccgatggcctcggccg	CRISPR spacer
ctcgacggcggccgtgatggcctcgggat	Protospacer
  .********** .***********

81. spacer 22.1|11610280|31|NZ_CP022098|CRISPRCasFinder matches to MN693926 (Marine virus AFVG_250M186, complete genome) position: , mismatch: 8, identity: 0.742

gcatcgcacagcaacacaccagcatcaggta	CRISPR spacer
tttacgttcagcaacccaccggcatcaggta	Protospacer
 .  **. ******* ****.**********

82. spacer 1.1|43665|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP031793 (Klebsiella pneumoniae strain INF116-sc-2279924 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.71

gttggccgtgggggcgggcgcgttgccgagg	CRISPR spacer
cctggccgtgggggcgggcgtgtttgacggt	Protospacer
 .******************.***    .*

83. spacer 1.1|43665|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP021946 (Klebsiella pneumoniae strain AR_0152 plasmid tig00000195, complete sequence) position: , mismatch: 9, identity: 0.71

gttggccgtgggggcgggcgcgttgccgagg	CRISPR spacer
cctggccgtgggggcgggcgtgtttgacggt	Protospacer
 .******************.***    .*

84. spacer 1.1|43665|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP013986 (Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

gttggccgtgggggcgggcgcgttgccgagg	CRISPR spacer
cctggccgtgggggcgggcgtgtttgacggt	Protospacer
 .******************.***    .*

85. spacer 1.1|43665|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP045691 (Klebsiella pneumoniae strain TK421 plasmid pTK421_1, complete sequence) position: , mismatch: 9, identity: 0.71

gttggccgtgggggcgggcgcgttgccgagg	CRISPR spacer
cctggccgtgggggcgggcgtgtttgacggt	Protospacer
 .******************.***    .*

86. spacer 1.1|43665|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP032357 (Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_res, complete sequence) position: , mismatch: 9, identity: 0.71

gttggccgtgggggcgggcgcgttgccgagg	CRISPR spacer
cctggccgtgggggcgggcgtgtttgacggt	Protospacer
 .******************.***    .*

87. spacer 1.1|43665|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP011518 (Pandoraea oxalativorans strain DSM 23570 plasmid pPO70-1, complete sequence) position: , mismatch: 9, identity: 0.71

gttggccgtgggggcgggcgcgttgccgagg	CRISPR spacer
acgggccgtcggcgcgggcgcgttgcagccc	Protospacer
.. ****** ** ************* *

88. spacer 1.1|43665|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP032342 (Azospirillum brasilense strain MTCC4038 plasmid p3, complete sequence) position: , mismatch: 9, identity: 0.71

gttggccgtgggggcgggcgcgttgccgagg	CRISPR spacer
ggacgccgtggccgcgggcgcgttgcccgcc	Protospacer
*   *******  ************** .

89. spacer 1.1|43665|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP033321 (Azospirillum brasilense strain Cd plasmid p3, complete sequence) position: , mismatch: 9, identity: 0.71

gttggccgtgggggcgggcgcgttgccgagg	CRISPR spacer
ggacgccgtggccgcgggcgcgttgcccgcc	Protospacer
*   *******  ************** .

90. spacer 1.1|43665|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP033315 (Azospirillum brasilense strain Sp 7 plasmid p3, complete sequence) position: , mismatch: 9, identity: 0.71

gttggccgtgggggcgggcgcgttgccgagg	CRISPR spacer
ggacgccgtggccgcgggcgcgttgcccgcc	Protospacer
*   *******  ************** .

91. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to LR606148 (Rhizobium sp. Q54 genome assembly, plasmid: 5) position: , mismatch: 9, identity: 0.71

gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
aaaccgctggtgtcggccgggatggtggcga	Protospacer
.    * ******* ************ **

92. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP039693 (Agrobacterium larrymoorei strain CFBP5473 plasmid pAlCFBP5473, complete sequence) position: , mismatch: 9, identity: 0.71

gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
aaaccgctggtgtcggccgggatggtggcga	Protospacer
.    * ******* ************ **

93. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP039913 (Agrobacterium tumefaciens strain CFBP6625 plasmid pAtCFBP6625b, complete sequence) position: , mismatch: 9, identity: 0.71

gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
aaaccgctggtgtccgccggcatggtggcga	Protospacer
.    * ************* ****** **

94. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NZ_LR723672 (Rhizobium flavum strain YW14 plasmid 3) position: , mismatch: 9, identity: 0.71

gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
aaaccgctggtgtcggccgggatggtggcga	Protospacer
.    * ******* ************ **

95. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to CP047390 (Agrobacterium sp. CGMCC 11546 plasmid pB) position: , mismatch: 9, identity: 0.71

gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
aaaccgttggtgtcggccgggatggtggcga	Protospacer
.    * ******* ************ **

96. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NC_021909 (Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1e, complete sequence) position: , mismatch: 9, identity: 0.71

gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
aaaccgttggtgtcggccgggatggtggcga	Protospacer
.    * ******* ************ **

97. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP021815 (Sinorhizobium meliloti strain M270 plasmid accessoryA, complete sequence) position: , mismatch: 9, identity: 0.71

gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
aaaccgctggtgtcggccgggatggtggcga	Protospacer
.    * ******* ************ **

98. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP016451 (Sinorhizobium sp. RAC02 plasmid pBSY16_2, complete sequence) position: , mismatch: 9, identity: 0.71

gccggga----tggtgtccgccgggatggtgtcgc	CRISPR spacer
----aaacccttggtgtcggccgggatggtggcga	Protospacer
    ..*    ******* ************ **

99. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NC_011982 (Agrobacterium vitis S4 plasmid pTiS4, complete sequence) position: , mismatch: 10, identity: 0.677

gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
aaaccattggtgtcggccgggatggtggcga	Protospacer
.    . ******* ************ **

100. spacer 7.1|1890314|31|NZ_CP022098|CRISPRCasFinder matches to NZ_CP034999 (Rhizobium acidisoli strain FH23 plasmid pRapFH23a, complete sequence) position: , mismatch: 10, identity: 0.677

gccgggatggtgtccgccgggatggtgtcgc	CRISPR spacer
aaaccattggtgtcggccgggatggtggcga	Protospacer
.    . ******* ************ **

101. spacer 17.1|6605195|33|NZ_CP022098|CRISPRCasFinder matches to NZ_CP029830 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.697

gtgagctgctcgtcgccggggtggacacgaaga	CRISPR spacer
gcgagctgttcgtcgccggggtcgacgtcttcc	Protospacer
*.******.************* ***..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

10480057 : 10529503

Acanthocystis_turfacea_Chlorella_virus(20.0%)

protease,plate

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095990406.1\|10480057_10481086_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_095990407.1\|10481040_10482858_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_095990408.1\|10482907_10483366_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_095990409.1\|10483540_10484041_+	hypothetical protein	NA	NA	NA	NA
WP_095990410.1\|10484147_10485644_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_095990411.1\|10485689_10486199_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_095990412.1\|10486284_10486743_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_095990413.1\|10486771_10487881_-	type VI secretion system protein TssA	NA	NA	NA	NA
WP_095990414.1\|10487883_10489251_-	hypothetical protein	NA	NA	NA	NA
WP_157758974.1\|10489247_10489940_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_095990416.1\|10490035_10491352_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_095990417.1\|10491582_10493652_+	PHB depolymerase family esterase	NA	NA	NA	NA
WP_095990418.1\|10493917_10494832_+	hypothetical protein	NA	NA	NA	NA
WP_095990419.1\|10494906_10495908_+	carbon-nitrogen hydrolase family protein	M1HCD5	Acanthocystis_turfacea_Chlorella_virus	3.6e-08	26.6
WP_157758975.1\|10496040_10496409_+	hypothetical protein	NA	NA	NA	NA
WP_095990421.1\|10496875_10497898_+	glycoside hydrolase family 5 protein	NA	NA	NA	NA
WP_095992558.1\|10498046_10498769_+	HugZ family protein	NA	NA	NA	NA
WP_157758976.1\|10498787_10499102_-	hypothetical protein	NA	NA	NA	NA
WP_157758977.1\|10499025_10499406_-	NAD(P)-binding protein	NA	NA	NA	NA
WP_095990423.1\|10499504_10503578_-	A-macroglobulin complement component	NA	NA	NA	NA
WP_095990424.1\|10503697_10504597_-	DMT family transporter	NA	NA	NA	NA
WP_095990425.1\|10504742_10505636_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_095990426.1\|10505729_10506491_-	2OG-Fe(II) oxygenase	NA	NA	NA	NA
WP_095990427.1\|10506702_10507485_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_095990428.1\|10507837_10508119_-	hypothetical protein	NA	NA	NA	NA
WP_095990429.1\|10509094_10510117_+	hypothetical protein	NA	NA	NA	NA
WP_095990430.1\|10510264_10511182_-	hypothetical protein	NA	NA	NA	NA
WP_095990431.1\|10511301_10511760_-	hypothetical protein	NA	NA	NA	NA
WP_095990433.1\|10513004_10513799_-	ABC transporter permease	NA	NA	NA	NA
WP_095990434.1\|10513802_10514606_-	ABC transporter permease	NA	NA	NA	NA
WP_095990435.1\|10514602_10515598_-	ATP-binding cassette domain-containing protein	A0A2R8FG22	Brazilian_cedratvirus	2.9e-18	31.1
WP_095990436.1\|10515662_10516862_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_095990437.1\|10516862_10517354_-	peptidylprolyl isomerase	NA	NA	NA	NA
WP_095990438.1\|10517400_10518792_-	M20/M25/M40 family metallo-hydrolase	NA	NA	NA	NA
WP_095992559.1\|10518902_10519274_+	response regulator	NA	NA	NA	NA
WP_095990439.1\|10519294_10520194_+	molecular chaperone DnaJ	NA	NA	NA	NA
WP_095992560.1\|10520259_10521861_+	GAF domain-containing protein	A0A1B0VMK3	Pseudomonas_phage	3.1e-09	27.6
WP_095990440.1\|10521868_10523014_-	RNA methyltransferase	NA	NA	NA	NA
WP_095990441.1\|10523085_10523970_+	oxidoreductase	NA	NA	NA	NA
WP_095992561.1\|10523947_10524922_-	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_095990442.1\|10524831_10525395_-	NifU family protein	NA	NA	NA	NA
WP_095990443.1\|10525579_10526152_+	DUF2378 family protein	NA	NA	NA	NA
WP_095990444.1\|10526160_10526601_+	hypothetical protein	NA	NA	NA	NA
WP_002622993.1\|10526859_10527186_+\|protease	ATP-dependent Clp protease adaptor ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	1.9e-14	46.9
WP_095990445.1\|10527190_10529503_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	4.0e-159	40.5

DBSCAN-SWA_2

10676689 : 10738887

Bacillus_phage(18.18%)

tRNA,transposase,integrase,head

attL 10703915:10703965|attR 10717345:10717395

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095990550.1\|10676689_10677577_+\|transposase	ISL3 family transposase	A9YX10	Burkholderia_phage	1.2e-36	33.6
WP_095990551.1\|10677548_10678196_-	hypothetical protein	NA	NA	NA	NA
WP_095990552.1\|10678681_10678876_-	hypothetical protein	NA	NA	NA	NA
WP_095990553.1\|10679248_10681933_-	alpha-1,2-mannosidase	E5ESH9	Bathycoccus_sp._RCC1105_virus	5.9e-05	33.0
WP_095990554.1\|10682125_10683679_-	hypothetical protein	NA	NA	NA	NA
WP_095990555.1\|10683688_10684366_-	hypothetical protein	NA	NA	NA	NA
WP_095992573.1\|10684355_10685582_-	hypothetical protein	NA	NA	NA	NA
WP_095990556.1\|10685980_10688617_+	alpha-amylase	NA	NA	NA	NA
WP_095990557.1\|10688712_10689900_+	cytochrome P450	NA	NA	NA	NA
WP_095990558.1\|10689927_10690344_-	response regulator	W8CYM9	Bacillus_phage	1.8e-06	33.6
WP_095990559.1\|10690340_10691456_-	PAS domain-containing protein	W8CYF6	Bacillus_phage	3.2e-21	25.7
WP_095990560.1\|10691564_10692110_-	DUF1697 domain-containing protein	NA	NA	NA	NA
WP_095990561.1\|10692150_10693620_-	MFS transporter	NA	NA	NA	NA
WP_095992574.1\|10693764_10694586_-	mechanosensitive ion channel family protein	NA	NA	NA	NA
WP_095990562.1\|10694764_10696297_-	acetyl-CoA hydrolase	NA	NA	NA	NA
WP_095990563.1\|10696554_10696941_+	BlaI/MecI/CopY family transcriptional regulator	NA	NA	NA	NA
WP_095990564.1\|10696937_10698725_+	M56 family metallopeptidase	NA	NA	NA	NA
WP_095990565.1\|10698774_10699053_-	hypothetical protein	NA	NA	NA	NA
WP_095990566.1\|10699204_10699912_-	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_095990567.1\|10700016_10700451_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_095990568.1\|10700432_10701023_-	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_157758986.1\|10701395_10701566_+	hypothetical protein	NA	NA	NA	NA
WP_095990569.1\|10701682_10702288_+	glutathione S-transferase family protein	NA	NA	NA	NA
WP_095990570.1\|10702336_10703296_+	hemerythrin domain-containing protein	NA	NA	NA	NA
WP_095990571.1\|10703522_10703762_-	addiction module protein	NA	NA	NA	NA
10703915:10703965	attL	NA	NA	NA	NA
WP_095990573.1\|10704481_10705261_-	hypothetical protein	NA	NA	NA	NA
WP_095990574.1\|10705263_10705851_-	hypothetical protein	NA	NA	NA	NA
WP_095990575.1\|10705863_10706511_-	hypothetical protein	NA	NA	NA	NA
WP_095984753.1\|10706765_10707155_+\|transposase	transposase	NA	NA	NA	NA
WP_095991877.1\|10707202_10707493_+	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	1.3e-06	36.1
WP_095984753.1\|10709361_10709751_+\|transposase	transposase	NA	NA	NA	NA
WP_095991877.1\|10709798_10710089_+	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	1.3e-06	36.1
WP_095984752.1\|10710137_10711805_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	8.9e-60	36.8
WP_095990576.1\|10711949_10712678_+	hypothetical protein	NA	NA	NA	NA
WP_095990577.1\|10713132_10715418_+	hypothetical protein	NA	NA	NA	NA
WP_095990578.1\|10715410_10715626_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_095990579.1\|10715673_10716846_+\|integrase	site-specific integrase	Q6X9Q1	Myxococcus_phage	3.4e-42	35.0
WP_095990581.1\|10717674_10718076_+	response regulator	NA	NA	NA	NA
10717345:10717395	attR	NA	NA	NA	NA
WP_095990582.1\|10718064_10718718_-	ribulose-phosphate 3-epimerase	NA	NA	NA	NA
WP_095990583.1\|10718899_10720417_+	GAF domain-containing protein	NA	NA	NA	NA
WP_095990584.1\|10720465_10721896_-	pyruvate kinase	NA	NA	NA	NA
WP_095990585.1\|10721984_10722872_-	hypothetical protein	NA	NA	NA	NA
WP_095990586.1\|10722947_10723511_-	hypothetical protein	NA	NA	NA	NA
WP_095990587.1\|10723507_10724968_-	DUF814 domain-containing protein	M1HNF8	Acanthocystis_turfacea_Chlorella_virus	7.6e-07	38.0
WP_095990588.1\|10725057_10725282_-	excinuclease ABC subunit A	NA	NA	NA	NA
WP_095990589.1\|10725636_10726977_+	glycoside hydrolase family 1 protein	A0A0B5JD41	Pandoravirus	1.5e-46	32.2
WP_095990590.1\|10726955_10727975_-\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_095990591.1\|10728066_10729500_+	peptidase M50	NA	NA	NA	NA
WP_095990592.1\|10729584_10730607_+	stearoyl-CoA 9-desaturase	F2NZ38	Diadromus_pulchellus_ascovirus	1.3e-16	30.6
WP_095990593.1\|10730748_10732845_+	chloride channel protein	NA	NA	NA	NA
WP_095990595.1\|10733609_10735892_-	nitric-oxide reductase large subunit	NA	NA	NA	NA
WP_095990596.1\|10736105_10736915_+	glycoside hydrolase family 16 protein	NA	NA	NA	NA
WP_095992575.1\|10736927_10738160_-	MFS transporter	NA	NA	NA	NA
WP_095990597.1\|10738284_10738887_-\|head	head protein	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: NZ_CP022098.1|WP_095990578.1|10715410_10715626_+|helix-turn-helix-domain-containing-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP022098.1|WP_095990578.1|10715410_10715626_+|helix-turn-helix-domain-containing-protein

10715410_10715626_+

71 aa aa

10676689-10738887

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP022098_15	Orphan	15.2\|5454245\|19\|NZ_CP022098\|CRT	5454245-5454263	19	10716500-10716518	1

1. spacer 15.2|5454245|19|NZ_CP022098|CRT matches to NZ_CP022098 position: 10716500-10716518, mismatch: 1

tatgccgggccctggggcg	CRISPR spacer
tacgccgggccctggggcg	Protospacer
**.****************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP022098

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information