CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP017115	Staphylococcus aureus strain FORC_045, complete genome	13 crisprs	cas3,DEDDh,DinG,csa3,WYL	4	4	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP017115_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017115_1

811808-811888

Unclear

Consensus_repeat	Method
TTCTTTATGTTGGGGCCCCGCCAACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP017115_1

>merge|NZ_CP017115|1|811808-811888|CRISPRCasFinder
TTCTTTATGTTGGGGCCCCGCCAACTTGCATTGTTTGTAGAATTTCTTTTCGAAATTCTTTATGTTGGGGCCCCGCCAACT

>NZ_CP017115|1|1|811808-811888|CRISPRCasFinder
TTCTTTATGTTGGGGCCCCGCCAACT	TGCATTGTTTGTAGAATTTCTTTTCGAAA
TTCTTTATGTTGGGGCCCCGCCAACT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017115.1\|WP_000538141.1\|805526_806177_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|378993
NZ_CP017115.1\|WP_000513312.1\|813062_813902_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
NZ_CP017115.1\|WP_000006551.1\|819622_820567_+\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NZ_CP017115.1\|WP_000638419.1\|806173_806410_+\|CsbA-family-protein	unknown	unknown	gnl\|CDD\|227234
NZ_CP017115.1\|WP_000506531.1\|800148_802680_+\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
NZ_CP017115.1\|WP_000229237.1\|806678_808664_+\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
NZ_CP017115.1\|WP_000816305.1\|821969_822872_-\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|224015
NZ_CP017115.1\|WP_010956549.1\|802994_804105_+\|peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
NZ_CP017115.1\|WP_000617735.1\|799162_799735_+\|ribosome-associated-translation-inhibitor-RaiA	unknown	unknown	gnl\|CDD\|224461
NZ_CP017115.1\|WP_000369722.1\|817608_818520_+\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|224574
NZ_CP017115.1\|WP_000134963.1\|815908_816844_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NZ_CP017115.1\|WP_001049165.1\|821139_821727_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
NZ_CP017115.1\|WP_001248939.1\|818516_819512_+\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NZ_CP017115.1\|WP_001224793.1\|813909_814395_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_CP017115.1\|WP_000662681.1\|808671_811518_+\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_CP017115.1\|WP_000057543.1\|814402_815842_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
NZ_CP017115.1\|WP_000753321.1\|804513_805353_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP017115.1\|WP_072360986.1\|804258_804366_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_000958224.1\|812124_813057_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
NZ_CP017115.1\|WP_001790092.1\|802721_802826_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP017115.1\|WP_000538141.1\|805526_806177_+\|HD-domain-containing-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
NZ_CP017115.1\|WP_000513312.1\|813062_813902_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	4.82832e-120
NZ_CP017115.1\|WP_000638419.1\|806173_806410_+\|CsbA-family-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
NZ_CP017115.1\|WP_000506531.1\|800148_802680_+\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NZ_CP017115.1\|WP_000229237.1\|806678_808664_+\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP017115.1\|WP_000816305.1\|821969_822872_-\|TIGR01777-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	1.79553e-154
NZ_CP017115.1\|WP_010956549.1\|802994_804105_+\|peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
NZ_CP017115.1\|WP_000617735.1\|799162_799735_+\|ribosome-associated-translation-inhibitor-RaiA	gnl\|CDD\|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	1.13584e-37
NZ_CP017115.1\|WP_000369722.1\|817608_818520_+\|RNase-adapter-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
NZ_CP017115.1\|WP_000134963.1\|815908_816844_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
NZ_CP017115.1\|WP_001049165.1\|821139_821727_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
NZ_CP017115.1\|WP_001248939.1\|818516_819512_+\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
NZ_CP017115.1\|WP_001224793.1\|813909_814395_+\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
NZ_CP017115.1\|WP_000662681.1\|808671_811518_+\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_CP017115.1\|WP_000057543.1\|814402_815842_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.14043e-06
NZ_CP017115.1\|WP_000753321.1\|804513_805353_+\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.82721e-42
NZ_CP017115.1\|WP_000958224.1\|812124_813057_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
NZ_CP017115.1\|WP_000006551.1\|819622_820567_+\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153

>NZ_CP017115.1|WP_000662681.1|808671_811518_+|excinuclease-ABC-subunit-UvrA
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>NZ_CP017115.1|WP_000229237.1|806678_808664_+|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIEEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>NZ_CP017115.1|WP_000638419.1|806173_806410_+|CsbA-family-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>NZ_CP017115.1|WP_000538141.1|805526_806177_+|HD-domain-containing-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>NZ_CP017115.1|WP_000753321.1|804513_805353_+|CHAP-domain-containing-protein
MKKTLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKTPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>NZ_CP017115.1|WP_072360986.1|804258_804366_+|hypothetical-protein
MYLLKQHMQCAFSNITYGDFQGIELIVENVLNYMV
>NZ_CP017115.1|WP_010956549.1|802994_804105_+|peptide-chain-release-factor-2
MELSEIKRNIDKYNQDLTQIRGSLDLENKETNIQEYEEMMAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
>NZ_CP017115.1|WP_001790092.1|802721_802826_+|hypothetical-protein
MLWEESFYFTSVKYFKKCEEVVKRCYVLSFKKSV
>NZ_CP017115.1|WP_000506531.1|800148_802680_+|preprotein-translocase-subunit-SecA
MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
>NZ_CP017115.1|WP_000617735.1|799162_799735_+|ribosome-associated-translation-inhibitor-RaiA
MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ
>NZ_CP017115.1|WP_000958224.1|812124_813057_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>NZ_CP017115.1|WP_000513312.1|813062_813902_+|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYVENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEKLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>NZ_CP017115.1|WP_001224793.1|813909_814395_+|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>NZ_CP017115.1|WP_000057543.1|814402_815842_+|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>NZ_CP017115.1|WP_000134963.1|815908_816844_+|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>NZ_CP017115.1|WP_000369722.1|817608_818520_+|RNase-adapter-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>NZ_CP017115.1|WP_001248939.1|818516_819512_+|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>NZ_CP017115.1|WP_000006551.1|819622_820567_+|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>NZ_CP017115.1|WP_001049165.1|821139_821727_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>NZ_CP017115.1|WP_000816305.1|821969_822872_-|TIGR01777-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKVLFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGMILSNEGGALQTMKLPYKYYIGGRLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE

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Crispr_ID: NZ_CP017115_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017115_2

859270-859351

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP017115_2

>merge|NZ_CP017115|2|859270-859351|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGAGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>NZ_CP017115|2|2|859270-859351|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGAGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017115.1\|WP_000150012.1\|855262_855979_+\|type-I-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
NZ_CP017115.1\|WP_000974464.1\|854692_855115_-\|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
NZ_CP017115.1\|WP_000589549.1\|857214_857571_+\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
NZ_CP017115.1\|WP_001183856.1\|864164_865016_-\|DUF368-domain-containing-protein	unknown	unknown	gnl\|CDD\|224946
NZ_CP017115.1\|WP_000732326.1\|862562_863384_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_CP017115.1\|WP_000569884.1\|853799_854294_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
NZ_CP017115.1\|WP_001018962.1\|859906_860293_+\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
NZ_CP017115.1\|WP_000255544.1\|853027_853645_-\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
NZ_CP017115.1\|WP_000807671.1\|867624_868866_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NZ_CP017115.1\|WP_000290489.1\|857728_858109_+\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_CP017115.1\|WP_000662306.1\|858172_858286_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_001147953.1\|856750_857071_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP017115.1\|WP_000520233.1\|861849_862545_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NZ_CP017115.1\|WP_000205570.1\|866202_867510_+\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NZ_CP017115.1\|WP_000422910.1\|856061_856601_+\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
NZ_CP017115.1\|WP_000752917.1\|863737_863932_+\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_CP017115.1\|WP_000571218.1\|860831_861857_+\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NZ_CP017115.1\|WP_000168845.1\|865343_866105_+\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NZ_CP017115.1\|WP_001065801.1\|860285_860582_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP017115.1\|WP_000932228.1\|858287_859166_+\|DUF1963-domain-containing-protein	unknown	unknown	gnl\|CDD\|226395

Protein	Function_ID	Function_description	E-value
NZ_CP017115.1\|WP_000150012.1\|855262_855979_+\|type-I-3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	1.05028e-146
NZ_CP017115.1\|WP_000974464.1\|854692_855115_-\|organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	1.70812e-60
NZ_CP017115.1\|WP_000589549.1\|857214_857571_+\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
NZ_CP017115.1\|WP_000732326.1\|862562_863384_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	2.15951e-112
NZ_CP017115.1\|WP_000569884.1\|853799_854294_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
NZ_CP017115.1\|WP_001018962.1\|859906_860293_+\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
NZ_CP017115.1\|WP_000255544.1\|853027_853645_-\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	1.6558e-60
NZ_CP017115.1\|WP_000807671.1\|867624_868866_+\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_CP017115.1\|WP_000290489.1\|857728_858109_+\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	2.95269e-69
NZ_CP017115.1\|WP_001183856.1\|864164_865016_-\|DUF368-domain-containing-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	9.12578e-76
NZ_CP017115.1\|WP_001147953.1\|856750_857071_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.31384e-24
NZ_CP017115.1\|WP_000520233.1\|861849_862545_+\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	9.67625e-100
NZ_CP017115.1\|WP_000205570.1\|866202_867510_+\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	9.26601e-136
NZ_CP017115.1\|WP_000422910.1\|856061_856601_+\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	1.62265e-48
NZ_CP017115.1\|WP_000752917.1\|863737_863932_+\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.95583e-07
NZ_CP017115.1\|WP_000571218.1\|860831_861857_+\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	3.37873e-170
NZ_CP017115.1\|WP_000168845.1\|865343_866105_+\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.29081e-150
NZ_CP017115.1\|WP_001065801.1\|860285_860582_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
NZ_CP017115.1\|WP_000932228.1\|858287_859166_+\|DUF1963-domain-containing-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	5.66518e-74

>NZ_CP017115.1|WP_000932228.1|858287_859166_+|DUF1963-domain-containing-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMVLKEMKEETLNQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLDNLPEQQELFPVKEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQAHLKSLDADNEDIPFSGAFSIEFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>NZ_CP017115.1|WP_000662306.1|858172_858286_+|hypothetical-protein
MKENLLGTIIWSIATFYYSRMMKIMNLAILKIKIGGS
>NZ_CP017115.1|WP_000290489.1|857728_858109_+|glycine-cleavage-system-protein-GcvH
MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQIEALLTAEKYSEMIGE
>NZ_CP017115.1|WP_000589549.1|857214_857571_+|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>NZ_CP017115.1|WP_001147953.1|856750_857071_-|thioredoxin-family-protein
MQAIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYKDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>NZ_CP017115.1|WP_000422910.1|856061_856601_+|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLSGFLYLTDLEEDMPKAPRKNRNLITLY
>NZ_CP017115.1|WP_000150012.1|855262_855979_+|type-I-3-dehydroquinate-dehydratase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFINDLYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGEPQAPGQIDVTDLKAQVTLY
>NZ_CP017115.1|WP_000974464.1|854692_855115_-|organic-hydroperoxide-resistance-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVSPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>NZ_CP017115.1|WP_000569884.1|853799_854294_-|GNAT-family-N-acetyltransferase
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>NZ_CP017115.1|WP_000255544.1|853027_853645_-|amino-acid-transporter
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIIAAGLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGEAQIMSPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGEMVGSIDKTGKLLTIINKLSSIIIIIVALMILQKLIQLLF
>NZ_CP017115.1|WP_001018962.1|859906_860293_+|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>NZ_CP017115.1|WP_001065801.1|860285_860582_+|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>NZ_CP017115.1|WP_000571218.1|860831_861857_+|methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEQGPVTQVFENPQHTVTKRFVKDDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>NZ_CP017115.1|WP_000520233.1|861849_862545_+|ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>NZ_CP017115.1|WP_000732326.1|862562_863384_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>NZ_CP017115.1|WP_000752917.1|863737_863932_+|CsbD-family-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
>NZ_CP017115.1|WP_001183856.1|864164_865016_-|DUF368-domain-containing-protein
MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTSLIIKYFIAGMCASSAMLLPGISGSFMLLVFGFYGTVMLAISEVVKLNFAGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>NZ_CP017115.1|WP_000168845.1|865343_866105_+|Fe-S-cluster-assembly-ATPase-SufC
MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>NZ_CP017115.1|WP_000205570.1|866202_867510_+|Fe-S-cluster-assembly-protein-SufD
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKYFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDENASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSLKSVVIGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
>NZ_CP017115.1|WP_000807671.1|867624_868866_+|cysteine-desulfurase
MAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDVDQLINALKQTKEFFSYEF

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Crispr_ID: NZ_CP017115_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017115_3

1041662-1041754

Orphan

Consensus_repeat	Method
AAAAGCCCCTAACAACTAAAAGTTGTAAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP017115_3

>merge|NZ_CP017115|3|1041662-1041754|CRISPRCasFinder
AAAAGCCCCTAACAACTAAAAGTTGTAAGGAAGAAGAGGGACACATGCGCCGAGCACATGCATAAAATCCCCTAACAACTAAAAGTTGTAAGG

>NZ_CP017115|3|3|1041662-1041754|CRISPRCasFinder
AAAAGCCCCTAACAACTAAAAGTTGTAAGG	AAGAAGAGGGACACATGCGCCGAGCACATGCAT
AAAATCCCCTAACAACTAAAAGTTGTAAGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017115.1\|WP_000514290.1\|1050856_1051519_+\|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|223643
NZ_CP017115.1\|WP_088607361.1\|1036878_1038126_+\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|237507
NZ_CP017115.1\|WP_000685063.1\|1043769_1044942_+\|class-I-SAM-dependent-rRNA-methyltransferase	unknown	unknown	gnl\|CDD\|224017
NZ_CP017115.1\|WP_000273252.1\|1038390_1039197_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NZ_CP017115.1\|WP_000483713.1\|1032289_1033774_+\|amidophosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235984
NZ_CP017115.1\|WP_000238663.1\|1034797_1035364_+\|phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|223376
NZ_CP017115.1\|WP_000666801.1\|1029457_1030129_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	unknown	unknown	gnl\|CDD\|235140
NZ_CP017115.1\|WP_000064214.1\|1041763_1041898_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_000437472.1\|1045691_1045958_+\|phosphocarrier-protein-HPr	unknown	unknown	gnl\|CDD\|237503
NZ_CP017115.1\|WP_001289618.1\|1047915_1048149_-\|glutaredoxin-family-protein	unknown	unknown	gnl\|CDD\|239274
NZ_CP017115.1\|WP_000040052.1\|1045960_1047679_+\|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl\|CDD\|224006
NZ_CP017115.1\|WP_000033477.1\|1040604_1041180_-\|ECF-transporter-S-component	unknown	unknown	gnl\|CDD\|227065
NZ_CP017115.1\|WP_000381849.1\|1048346_1049708_+\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
NZ_CP017115.1\|WP_000709290.1\|1035378_1036857_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
NZ_CP017115.1\|WP_000009069.1\|1042049_1043345_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_000030823.1\|1033766_1034795_+\|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl\|CDD\|235439
NZ_CP017115.1\|WP_000032727.1\|1030121_1032311_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	unknown	unknown	gnl\|CDD\|234921
NZ_CP017115.1\|WP_000505966.1\|1044995_1045538_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368297
NZ_CP017115.1\|WP_000921973.1\|1039189_1040590_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213192
NZ_CP017115.1\|WP_000638453.1\|1049704_1050724_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|224213

Protein	Function_ID	Function_description	E-value
NZ_CP017115.1\|WP_000514290.1\|1050856_1051519_+\|TrkA-family-potassium-uptake-protein	gnl\|CDD\|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	4.35421e-66
NZ_CP017115.1\|WP_088607361.1\|1036878_1038126_+\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|237507	PRK13790, PRK13790, phosphoribosylamine--glycine ligase; Provisional.	0
NZ_CP017115.1\|WP_000273252.1\|1038390_1039197_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	7.19598e-29
NZ_CP017115.1\|WP_000030823.1\|1033766_1034795_+\|phosphoribosylformylglycinamidine-cyclo-ligase	gnl\|CDD\|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
NZ_CP017115.1\|WP_000238663.1\|1034797_1035364_+\|phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|223376	COG0299, PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism].	2.03517e-91
NZ_CP017115.1\|WP_000666801.1\|1029457_1030129_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	gnl\|CDD\|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	2.73525e-140
NZ_CP017115.1\|WP_000483713.1\|1032289_1033774_+\|amidophosphoribosyltransferase	gnl\|CDD\|235984	PRK07272, PRK07272, amidophosphoribosyltransferase; Provisional.	0
NZ_CP017115.1\|WP_000437472.1\|1045691_1045958_+\|phosphocarrier-protein-HPr	gnl\|CDD\|237503	PRK13780, PRK13780, phosphocarrier protein HPr; Provisional.	2.44795e-51
NZ_CP017115.1\|WP_001289618.1\|1047915_1048149_-\|glutaredoxin-family-protein	gnl\|CDD\|239274	cd02976, NrdH, NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase activity that is dependent on TRX reductase, not glutathione (GSH). It is part of the NrdHIEF operon, where NrdEF codes for class Ib ribonucleotide reductase (RNR-Ib), an efficient enzyme at low oxygen levels. Under these conditions when GSH is mostly conjugated to spermidine, NrdH can still function and act as a hydrogen donor for RNR-Ib. It has been suggested that the NrdHEF system may be the oldest RNR reducing system, capable of functioning in a microaerophilic environment, where GSH was not yet available. NrdH from Corynebacterium ammoniagenes can form domain-swapped dimers, although it is unknown if this happens in vivo. Domain-swapped dimerization, which results in the blocking of the TRX reductase binding site, could be a mechanism for regulating the oxidation state of the protein.	1.21197e-16
NZ_CP017115.1\|WP_000040052.1\|1045960_1047679_+\|phosphoenolpyruvate--protein-phosphotransferase	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
NZ_CP017115.1\|WP_000033477.1\|1040604_1041180_-\|ECF-transporter-S-component	gnl\|CDD\|227065	COG4721, COG4721, ABC-type cobalt transport system, predicted permease component [Inorganic ion transport and metabolism].	4.34592e-70
NZ_CP017115.1\|WP_000381849.1\|1048346_1049708_+\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	2.48829e-165
NZ_CP017115.1\|WP_000709290.1\|1035378_1036857_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NZ_CP017115.1\|WP_000685063.1\|1043769_1044942_+\|class-I-SAM-dependent-rRNA-methyltransferase	gnl\|CDD\|224017	COG1092, COG1092, Predicted SAM-dependent methyltransferases [General function prediction only].	2.1836e-146
NZ_CP017115.1\|WP_000921973.1\|1039189_1040590_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	1.87437e-64
NZ_CP017115.1\|WP_000032727.1\|1030121_1032311_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	gnl\|CDD\|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0
NZ_CP017115.1\|WP_000505966.1\|1044995_1045538_+\|hypothetical-protein	gnl\|CDD\|368297	pfam05128, DUF697, Domain of unknown function (DUF697). Family of bacterial hypothetical proteins that is sometimes associated with GTPase domains.	0.00844137
NZ_CP017115.1\|WP_000638453.1\|1049704_1050724_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|224213	COG1294, AppB, Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion].	1.67944e-76

>NZ_CP017115.1|WP_000033477.1|1040604_1041180_-|ECF-transporter-S-component
MSKGLKLSEILVTVLISVVFAVIYNLWWFVYNGVQATGLHLEQLTNGVWFMAAIVCYLIIPKPGIALLAEFAAGAGETIIMGRFDIPTIVYAFIQGLACELVFAIFKYQSRSVMVAMLAGFCTAIAAFPIDYFYGYLNEVAGWNLTLFIVFRLISGAVVAGVLSYLLVKALDKTGVTKLFRPAAKEDYDNL
>NZ_CP017115.1|WP_000921973.1|1039189_1040590_-|ABC-transporter-ATP-binding-protein
MLKVSDLRLKYPSGQRKIFDHLNITIQDKEKVLLLGPSGCGKSTLLNVLSGIVPNLIELPMKYDELIVDPLSGVIFQDPDSQFCMPKVYEELAFVLENRQVPREDMDALIINALNMVNLNVTPETYIKDLSGGMKQKLAIVETILQQSKTLFLDEPTAMLDVQATEDLWTKLIELWEDQTVVIVEHKVKHIWNHVDRVILMDYNGNIIADECPEIILQKYVHLLSEYGVWHPRAWEFAPSRVDFPTTNSHLLQFKNGRIIRGKSTLLSFSDLEIGLGEWITITGANGSGKTTLLESIMQLIKYQGDVYFENQRLTKIKHAAKHMYLVYQNPELQFITNSVYDEINIHFNHLSKDQSDDETIQLLKLLDLQNVKDQHPYELSIGQKRRLSVATALSSKADIIFLDEPTFGLDSHNTFQLIKLFQKRINLGQSIVMVTHDDEIIERYPSRRLKISDGALLDCDGDTNV
>NZ_CP017115.1|WP_000273252.1|1038390_1039197_-|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MYEQWKVRQSFVDDVNIITKLFLGIILFFFIIFVHNFDFMLYITILMLVFLLMFNGTQFKITAIFITISIGFALLSSLFMILYGNGSHTILKFGFIHITTESLVRGLHVSLRTIAISFFGILIALTSQVVMIFYSLMQHLKVKSKVAYAFMAAIRMIPLMISSLIQLRRSLKMRYQMIDAANYRGLKRFKHLIIPLLSQNIRKAHQLSVAMESKGFRDGPRTYYYNVPFSYKDIIFIIVLIAIITLAYYCSITLPITGIDDVRLGRVG
>NZ_CP017115.1|WP_088607361.1|1036878_1038126_+|phosphoribosylamine--glycine-ligase
MNVLVIGAGGREHALAYKLNQSNLVKQVFAIPGNEAMTPIAEVHSEISESDHQAILDFAKRQNVDWVVIGPEQPLIDGLADILRANGFKVFGPNKQAAQIEGSKLFAKKIMEKYNIPTADYKEVERKKDALTYIENCELPVVVKKDGLAAGKGVIIADTIEAARSAIEIMYGDEEEGTVVFETFLEGEEFSLMTFVNGDLAVPFDCIAQDHKRAFDHDEGPNTGGMGAYCPVPHISDDVLKLTNETIAQPIAKAMLNEGYQFFGVLYIGAILTKNGPKVIEFNARFGDPEAQVLLSRMESDLMQHIIDLDEGKRTEFKWKNESIVGVMLASKGYPDAYEKGHKVSGFDLNENYFVSGLKKQGDTFVTSGGRVILAIGKGDNVQDAQRDAYEKVSQIQSDHLFYRHDIANKALQLK
>NZ_CP017115.1|WP_000709290.1|1035378_1036857_+|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MKKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYQEVLTRLRNDSLDESYRQSLMIKVFEHTAEYDEAIVRFFKGDKETLRYGENPQQSAYFVRTSNAKHTIAGAKQLHGKQLSYNNIKDADATLALVKKFDTPATVAVKHMNPCGVGIGDTIEQAFQHAYEADSQSIFGGIVALNRAVTPELAEQLHSIFLEVIIAPKFTDEALDILKQKKNVRLLEIDMTIDSNEEEFVSVSGGYLVQDKDNYVVPKEEMKVVTEVAPTDEQWEAMLLGWKVVPSVKSNAIILSNNKQTVGIGAGQMNRVGAAKIALERAIEINDHVALVSDGFFPMGDTVELAAQHGIKAIIQPGGSIKDQDSIDMANKHGIAMVVTGTRHFKH
>NZ_CP017115.1|WP_000238663.1|1034797_1035364_+|phosphoribosylglycinamide-formyltransferase
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEPKQFDSKAAYEQHLVSLLNEDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDCGMDTGEIIEQRQCDIRPDDSKEQLEEKVKKLEYELYPSVIAKIVK
>NZ_CP017115.1|WP_000030823.1|1033766_1034795_+|phosphoribosylformylglycinamidine-cyclo-ligase
MSKAYEQSGVNIHAGYEAVERMSSHVKRTMRKEVIGGLGGFGATFDLSQLNMTAPVLVSGTDGVGTKLKLAIDYGKHDSIGIDAVAMCVNDILTTGAEPLYFLDYIATNKVVPEVIEQIVKGISDACVETNTALIGGETAEMGEMYHEGEYDVAGFAVGAVEKDDYVDSSEVKEGQVVIGLASSGIHSNGYSLVRKLINESGIDLASNFDNRPFIDVFLEPTKLYVKPVLALKKEVSIKAMNHITGGGFYENIPRALPAGYAARIDTTSFPTPKIFDWLQQQGNIDTNEMYNIFNMGIGYTVIVDEKDASRALKILAEQNVEAYQIGHIMKNESTAIELLGV
>NZ_CP017115.1|WP_000483713.1|1032289_1033774_+|amidophosphoribosyltransferase
MFNYSGLNEECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIVVSDQNELKGERGLGLLTEAIKDDQMERLKGYQHAIGHVRYATSGNKGIENIQPFLYHFYDMSVGICHNGNLINAKSLRQNLEKQGAIFHSSSDTEVIMHLIRRSKAPTFEEALKESLRKVKGGFTFAILTKDALYGAVDPNAIRPLVVGKMKDGTYILASETCAIDVLGAEFVQDIHAGEYVVINDKGITVKSYTHHTTTAISAMEYIYFARPDSTIAGKNVHAVRKASGKKLAQESPVNADMVIGVPNSSLSAASGYAEEIGLPYEMGLVKNQYVARTFIQPTQELREQGVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRRIVKMLKDSGANKVHVRIASPEFMFPSFYGIDVSTTAELISASKSPEEIKDYIGADSLAYLSVDGLIESIGLDYDAPYSGLCVESFTGDYPAGLYDYEANYKAHLSHRQKQYISKNKHFFDSEGNLNV
>NZ_CP017115.1|WP_000032727.1|1030121_1032311_+|phosphoribosylformylglycinamidine-synthase-subunit-PurL
MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGDHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGYGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQERMLLVVEKGTEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKDYNTSKNDYTHIDVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAIAQCLTTQD
>NZ_CP017115.1|WP_000666801.1|1029457_1030129_+|phosphoribosylformylglycinamidine-synthase-subunit-PurQ
MKFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDYRETSLSGFDGVLIPGGFSFGDYLRSGAMASVAPIISEVKRLAAEGKPVLGVCNGFQILTEIGLLPGALLHNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDEIYQQLKANNQIILKYVNNPNGSYDDIAGIVNKKGNVCGMMPHPERALETLLGTDSGVKLFEAMVKSWREQHV
>NZ_CP017115.1|WP_000064214.1|1041763_1041898_-|hypothetical-protein
MSNENQNKKAAEKAKEVEEKLKDKKEEKTEDINQTKQDIQDTLN
>NZ_CP017115.1|WP_000009069.1|1042049_1043345_+|hypothetical-protein
MSFLRKHAEIIFSYLIGIVSLFTGLIILINLPLIKQLNGGKKVDTHVHNVWEFLNAFFSEIIKVMSRFIGNFPIVSAIVIIIFGILVMLIGHTLLRTIKYDYDISIFFLVIGIMYFIITLILMTQVYGFFAVIFIIPFTIHIGYIVYKDELNQENVKNHFMWIIVSYGISYLITQIALYGRIDANEIESIDILSVNAFFIIMWLLGQMAIWNFLFLRRALPLTKQELGEEEPELSRTSKGNVTNQTKIHLKQLQDKTTEYARKTRRSVDLDKIRAKRDKFKKKVNDIIDIQEDDIPDWMRKPKWVKPMYVELFCGVVIFLFTFLEFNNRNALFVSGDWKLSQTQYVIEWVTLLILLFIIIAYIATTLTFHLKGKFYYLQLFMGSILFFKLLTEFINIMIHGLLLSVFITPTLLLMLLAIIISYSLQLRERP
>NZ_CP017115.1|WP_000685063.1|1043769_1044942_+|class-I-SAM-dependent-rRNA-methyltransferase
MKIATLNKGKETKYFNGYPLIEEEDIYSQDHLKEGDIFQIVTDKSQYVATAYVGRQHKGLGWVLTYDKAQEINTAFFVKLFNTALAERDYYFNIDGTNAFRLFNAEGDGVGGLTIDNYDGHLLIQWYSKGIYKFKYAILEAVRKVFDYKSIYEKVRFKDSEYSGGFVEGDAPEFPIVIEENFTFYNVDLEDGLMTGIFLDQKEVRKKLRDQYAKERHVLNLFSYTGAFSVIAASEASSTTSVDLANRSRSLTEENFGLNAIDPKSQYIYVMDTFDFYKYAARHGHSYDTIVIDPPSFARNKKRTFSVQKDYDKLINGALNILSSEGTLLLCTNASVYPLKQFKNTIKKTLEESGVDYELTEVMGLPKDFKTHPHYKPSKYLKAVFVNIRH
>NZ_CP017115.1|WP_000505966.1|1044995_1045538_+|hypothetical-protein
MGFKNNLTSNLTNKIGNSVFKIENVDGKGAMPTTIQELRERRQRAEAIVKRKSLMSSTMSVVPIPGLDFGVDLKLMKDIIEDVNKIYGLDHKQVNSLGDDVKERIMSAAAIQGSQFIGKRISSAFLKIVIRDVAKRTAAKQTKWFPVVGQAVSASISYYFMNKIGKDHIQKCENVIKNVM
>NZ_CP017115.1|WP_000437472.1|1045691_1045958_+|phosphocarrier-protein-HPr
MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK
>NZ_CP017115.1|WP_000040052.1|1045960_1047679_+|phosphoenolpyruvate--protein-phosphotransferase
MSKLIKGIAASDGVAIAKAYLLVEPDLTFDKNEKVTDVEGEVAKFNSAIEASKVELTKIRNNAEVQLGADKAAIFDAHLLVLDDPELIQPIQDKIKNENANAATALTDVTTQFVTIFESMDNEYMKERAADIRDVSKRVLSHILGVELPNPSMIDESVVIVGNDLTPSDTAQLNKEFVQGFATNIGGRTSHSAIMSRSLEIPAIVGTKSITQEVKQGDMIIVDGLNGDVIVNPTEDELIAYQDKRERYFADKKELQKLRDADTVTVDGVHAELAANIGTPNDLPGVIENGAQGIGLYRTEFLYMGRDQMPTEEEQFEAYKEVLEAMDGKRVVVRTLDIGGDKELSYLNLPEEMNPFLGYRAIRLCLAQQDIFRPQLRALLRASVYGKLNIMFPMVATINEFREAKAILLEEKENLKNEGHDISDDIELGIMVEIPATAALADVFAKEVDFFSIGTNDLIQYTLAADRMSERVSYLYQPYNPSILRLVKQVIEASHKEGKWTGMCGEMAGDETAIPLLLGLGLDEFSMSATSILKARRQINGLSKNEMTELANRAVDCATQEEVIELVNNYVK
>NZ_CP017115.1|WP_001289618.1|1047915_1048149_-|glutaredoxin-family-protein
MSEIIVYTQNDCPPCTFVKNYLNEHQIDFEERNINNQQYRNEMIDFDAFSTPFILLNGNPMYHVDLDEINKVLNIQD
>NZ_CP017115.1|WP_000381849.1|1048346_1049708_+|cytochrome-ubiquinol-oxidase-subunit-I
MDTVEISRFLTAMTLAVHIIFATIGVGMPLMFAIAEFLGIRKNDLQYIAMAKRWAKAYTITVAVGVVTGTIIGLQLSLIWPTFMEMGGHVIALPLFMETFAFFFEAIFLSIYLYTWDRFKNKWTHFLISIPVIIGGSFSAFFITSVNSFMNTPAGFELKNGKMVNVQPIEAMFNPSFIVRSFHVITTAGMTMAFVIASIAAFKLLRNRQPKDTVYHKKALKMSMIVGFFSTLLSMLAGDLSAKFLHKFQPEKLAAYEWHFDTSSHAKLLLFGVLDEKTQQVKGAIELPGLLSFLADNSVKTKVQGLNDFPKSLHPPMIVHYFFDLMVTMGILCFVISGVYVLTLMFKKLRKFSTHKWMLYGILLTGPASMLAIEFGWFLTEMGRQPWIVRGYMRVAEAATQAGGITFVTILFGILYIILMYTCAYVLIRMFKNKPAYEDVNRLAKKQGGEIEK
>NZ_CP017115.1|WP_000638453.1|1049704_1050724_+|cytochrome-d-ubiquinol-oxidase-subunit-II
MIYAFIGITVLWLFLFCYIIIASIDFGAGFFALHSKLTGDEKKINHLISRYLNPVWEVTNVFFVFFFVGFVGFFPESIKYLGTVLLIPGSIALIMISLRNSFYAFENYGQDTKLAWMIMYGVSGLLIPASLSTALTITEGGYINVRNNVIDLDWVQLLLSPFAWSVVFLAIISVLYISSGFLTYYAKKANDEPAYNLTRQWHIFLGPPMIIICLFVFLSLRIQNSEHFYSAVFDYWWMFAISFLFFALASLLTFFKKKHGLAFVFVILQMMFAFFGYGISKLPYLLYPFVKITDAYVNPEMGWTLVIVFILGLLLLLPSLILLLRLFVFDKEYVEGKKS
>NZ_CP017115.1|WP_000514290.1|1050856_1051519_+|TrkA-family-potassium-uptake-protein
MGKEYVVIGLGRFGGSIVRELNALDMDVMAIDHDENRVNEYSDIATHAVVADTTDEAVMKSLGIRNFDHVIVAIGENIQSSTLTTLILKELGVKKVTAKAQNDYHAKILNKIGADTVVHPERDMGRRIAHNVASASVLDYLELADEHSIVELKATEKMAGQSIIDLDIRAQYGINIIAIKRGKEFIISPNPNINLEIGDILIMIGHDNDLNRFEKNIATR

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Crispr_ID: NZ_CP017115_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017115_4

1198837-1198929

Orphan

Consensus_repeat	Method
TAAGAAACACTAATCAATAAATTGATAAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP017115_4

>merge|NZ_CP017115|4|1198837-1198929|CRISPRCasFinder
TAAGAAACACTAATCAATAAATTGATAAGAAGATTAGAGGAACGCTTGAGCTAAAGCTCATGCATAAGAAACACTAATCAATAAATTGATAAG

>NZ_CP017115|4|4|1198837-1198929|CRISPRCasFinder
TAAGAAACACTAATCAATAAATTGATAAG	AAGATTAGAGGAACGCTTGAGCTAAAGCTCATGCA
TAAGAAACACTAATCAATAAATTGATAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017115.1\|WP_000167269.1\|1197915_1198650_+\|3-oxoacyl-[acyl-carrier-protein]-reductase	unknown	unknown	gnl\|CDD\|235500
NZ_CP017115.1\|WP_000426914.1\|1199019_1199253_+\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|179197
NZ_CP017115.1\|WP_000572223.1\|1182409_1183717_+\|16S-rRNA-(cytosine(967)-C(5))-methyltransferase-RsmB	unknown	unknown	gnl\|CDD\|237857
NZ_CP017115.1\|WP_000915244.1\|1209207_1211814_-\|YfhO-family-protein	unknown	unknown	gnl\|CDD\|226888
NZ_CP017115.1\|WP_000517908.1\|1190328_1190517_-\|50S-ribosomal-protein-L28	unknown	unknown	gnl\|CDD\|234736
NZ_CP017115.1\|WP_001548538.1\|1195443_1196016_+\|transcription-factor-FapR	unknown	unknown	gnl\|CDD\|179847
NZ_CP017115.1\|WP_000626905.1\|1183719_1184814_+\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	unknown	unknown	gnl\|CDD\|237717
NZ_CP017115.1\|WP_000579564.1\|1185560_1187555_+\|serine/threonine-protein-kinase-Stk1	unknown	unknown	gnl\|CDD\|270916
NZ_CP017115.1\|WP_000171418.1\|1190958_1191333_+\|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl\|CDD\|224221
NZ_CP017115.1\|WP_157665722.1\|1213082_1213781_+\|ribonuclease-HII	unknown	unknown	gnl\|CDD\|260003
NZ_CP017115.1\|WP_000672867.1\|1217426_1218671_+\|FemA/FemB-family-glycyltransferase-FmhC	unknown	unknown	gnl\|CDD\|367067
NZ_CP017115.1\|WP_088607369.1\|1187782_1188658_+\|ribosome-small-subunit-dependent-GTPase-A	unknown	unknown	gnl\|CDD\|224084
NZ_CP017115.1\|WP_000888498.1\|1184820_1185564_+\|protein-serine/threonine-phosphatase-Stp1	unknown	unknown	gnl\|CDD\|223704
NZ_CP017115.1\|WP_000239748.1\|1196020_1197007_+\|phosphate-acyltransferase-PlsX	unknown	unknown	gnl\|CDD\|235414
NZ_CP017115.1\|WP_000236715.1\|1212214_1213099_+\|ribosome-biogenesis-GTPase-YlqF	unknown	unknown	gnl\|CDD\|236570
NZ_CP017115.1\|WP_001041666.1\|1216280_1217399_+\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|366664
NZ_CP017115.1\|WP_157665723.1\|1204513_1204597_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234647
NZ_CP017115.1\|WP_001020801.1\|1213957_1215124_+\|ADP-forming-succinate--CoA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234813
NZ_CP017115.1\|WP_000110251.1\|1215145_1216054_+\|succinate--CoA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|180194
NZ_CP017115.1\|WP_000593192.1\|1218843_1219716_+\|DNA-protecting-protein-DprA	unknown	unknown	gnl\|CDD\|223829

Protein	Function_ID	Function_description	E-value
NZ_CP017115.1\|WP_000167269.1\|1197915_1198650_+\|3-oxoacyl-[acyl-carrier-protein]-reductase	gnl\|CDD\|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	3.68137e-140
NZ_CP017115.1\|WP_000426914.1\|1199019_1199253_+\|acyl-carrier-protein	gnl\|CDD\|179197	PRK00982, acpP, acyl carrier protein; Provisional.	5.23888e-31
NZ_CP017115.1\|WP_000572223.1\|1182409_1183717_+\|16S-rRNA-(cytosine(967)-C(5))-methyltransferase-RsmB	gnl\|CDD\|237857	PRK14902, PRK14902, 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB.	0
NZ_CP017115.1\|WP_000915244.1\|1209207_1211814_-\|YfhO-family-protein	gnl\|CDD\|226888	COG4485, COG4485, Predicted membrane protein [Function unknown].	0
NZ_CP017115.1\|WP_000517908.1\|1190328_1190517_-\|50S-ribosomal-protein-L28	gnl\|CDD\|234736	PRK00359, rpmB, 50S ribosomal protein L28; Reviewed.	1.3072e-18
NZ_CP017115.1\|WP_001548538.1\|1195443_1196016_+\|transcription-factor-FapR	gnl\|CDD\|179847	PRK04424, PRK04424, transcription factor FapR.	2.37773e-98
NZ_CP017115.1\|WP_000626905.1\|1183719_1184814_+\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	gnl\|CDD\|237717	PRK14455, PRK14455, ribosomal RNA large subunit methyltransferase N; Provisional.	0
NZ_CP017115.1\|WP_000579564.1\|1185560_1187555_+\|serine/threonine-protein-kinase-Stk1	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.57684e-117
NZ_CP017115.1\|WP_000171418.1\|1190958_1191333_+\|Asp23/Gls24-family-envelope-stress-response-protein	gnl\|CDD\|224221	COG1302, COG1302, Uncharacterized protein conserved in bacteria [Function unknown].	4.1554e-37
NZ_CP017115.1\|WP_157665722.1\|1213082_1213781_+\|ribonuclease-HII	gnl\|CDD\|260003	cd07182, RNase_HII_bacteria_HII_like, Bacterial Ribonuclease HII-like. This family includes mostly bacterial type 2 RNases H, with some eukaryotic members. Bacterial RNase HII has a role in primer removal based on its involvement in ribonucleotide-specific catalytic activity in the presence of RNA/DNA hybrid substrates. Several bacteria, such as Bacillus subtilis, have two different type II RNases H, RNases HII and HIII; double deletion of these leads to cellular lethality. It appears that type I and type II RNases H also have overlapping functions in cells, as over-expression of Escherichia coli RNase HII can complement an RNase HI deletion phenotype. In Leishmania mitochondria, of the four distinct RNase H genes (H1, HIIA, HIIB, HIIC), HIIC is essential for the survival of the parasite and thus can be a potential target for anti-leishmanial chemotherapy. Ribonuclease H (RNase H) is classified into two families, type I (prokaryotic RNase HI, eukaryotic RNase H1 and viral RNase H) and type II (prokaryotic RNase HII and HIII, and eukaryotic RNase H2). RNase H endonucleolytically hydrolyzes an RNA strand when it is annealed to a complementary DNA strand in the presence of divalent cations, in DNA replication and repair.	1.74257e-78
NZ_CP017115.1\|WP_000672867.1\|1217426_1218671_+\|FemA/FemB-family-glycyltransferase-FmhC	gnl\|CDD\|367067	pfam02388, FemAB, FemAB family. The femAB operon codes for two nearly identical approximately 50-kDa proteins involved in the formation of the Staphylococcal pentaglycine interpeptide bridge in peptidoglycan. These proteins are also considered as a factor influencing the level of methicillin resistance.	0
NZ_CP017115.1\|WP_088607369.1\|1187782_1188658_+\|ribosome-small-subunit-dependent-GTPase-A	gnl\|CDD\|224084	COG1162, COG1162, Predicted GTPases [General function prediction only].	8.53811e-128
NZ_CP017115.1\|WP_000888498.1\|1184820_1185564_+\|protein-serine/threonine-phosphatase-Stp1	gnl\|CDD\|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	7.74558e-90
NZ_CP017115.1\|WP_000239748.1\|1196020_1197007_+\|phosphate-acyltransferase-PlsX	gnl\|CDD\|235414	PRK05331, PRK05331, phosphate acyltransferase PlsX.	6.1953e-178
NZ_CP017115.1\|WP_000236715.1\|1212214_1213099_+\|ribosome-biogenesis-GTPase-YlqF	gnl\|CDD\|236570	PRK09563, rbgA, GTPase YlqF; Reviewed.	2.28339e-159
NZ_CP017115.1\|WP_001041666.1\|1216280_1217399_+\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|366664	pfam01476, LysM, LysM domain. The LysM (lysin motif) domain is about 40 residues long. It is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. The structure of this domain is known.	1.45655e-14
NZ_CP017115.1\|WP_157665723.1\|1204513_1204597_+\|hypothetical-protein	gnl\|CDD\|234647	PRK00118, PRK00118, putative DNA-binding protein; Validated.	0.000177219
NZ_CP017115.1\|WP_001020801.1\|1213957_1215124_+\|ADP-forming-succinate--CoA-ligase-subunit-beta	gnl\|CDD\|234813	PRK00696, sucC, ADP-forming succinate--CoA ligase subunit beta.	0
NZ_CP017115.1\|WP_000110251.1\|1215145_1216054_+\|succinate--CoA-ligase-subunit-alpha	gnl\|CDD\|180194	PRK05678, PRK05678, succinyl-CoA synthetase subunit alpha; Validated.	0
NZ_CP017115.1\|WP_000593192.1\|1218843_1219716_+\|DNA-protecting-protein-DprA	gnl\|CDD\|223829	COG0758, Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion].	7.99896e-103

>NZ_CP017115.1|WP_000167269.1|1197915_1198650_+|3-oxoacyl-[acyl-carrier-protein]-reductase
MTKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVAPGFIVSDMTDALSDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQTIHVNGGMYM
>NZ_CP017115.1|WP_000239748.1|1196020_1197007_+|phosphate-acyltransferase-PlsX
MVKLAIDMMGGDNAPDIVLEAVQKAVEDFKDLEIILFGDEKKYNLNHERIEFRHCSEKIEMEDEPVRAIKRKKDSSMVKMAEAVKSGEADGCVSAGNTGALMSAGLFIVGRIKGVARPALVVTLPTIDGKGFVFLDVGANADAKPEHLLQYAQLGDIYAQKIRGIDNPKISLLNIGTEPAKGNSLTKKSYELLNQDHSLNFVGNIEAKTLMDGDTDVVVTDGYTGNMVLKNLEGTAKSIGKMLKDTIMSSTKNKLAGAILKKDLAEFAKKMDYSEYGGSVLLGLEGTVVKAHGSSNAKAFYSAIRQAKIAGEQNIVQTMKETVGESNE
>NZ_CP017115.1|WP_001548538.1|1195443_1196016_+|transcription-factor-FapR
MRGETLKLKKDKRREAIRQQIDSNPFITDHELSDLFQVSIQTIRLDRTYLNIPELRKRIKLVAEKNYDQISSIEEQEFIGDLIQVNPNVKAQSILDITSDSVFHKTGIARGHVLFAQANSLCVALIKQPTVLTHESSIQFIEKVKLNDTVRAEARVVNQTAKHYYVEVKSYVKHTLVFKGNFKMFYDKRG
>NZ_CP017115.1|WP_000171418.1|1190958_1191333_+|Asp23/Gls24-family-envelope-stress-response-protein
MTLEISNDYGKIDISNEVIASVVGGKAVECYGIVGMASRQQVRDGIAEILGHENYAKGIKVTENNGVVDIDMYIIVSYGVKISEVANNVQSTVKYTLEKSLNVSVNSINIYVQGVRVNNTGKKA
>NZ_CP017115.1|WP_000517908.1|1190328_1190517_-|50S-ribosomal-protein-L28
MGKQCFVTGRKASTGNRRSHALNSTKRRWNANLQKVRILVDGKPKKVWVSARALKSGKVTRV
>NZ_CP017115.1|WP_088607369.1|1187782_1188658_+|ribosome-small-subunit-dependent-GTPase-A
MKTGRIVKSISGVYQVDVNGERFNTKPRGLFRKKKFSPVVGDIVEFEVQNINEGYIHQVFERENELKRPPVSNIDTLVIVMSAVEPNFSTQLLDRFLVIAHSYQLNARVLVTKKDKTPIEKQFEINELLKIYENIGYETEFIGNDDDRKKIVEAWPAGLIVLSGQSGVGKSTFLNHYRPELNLETNDISKSLNRGKHTTRHVELFERQNGYIADTPGFSALDFDHIDKDEIKDYFLELNRYGETCKFRNCNHIKEPNCNVKHQLEIGNIAQFRYDHYLQLFNEISNRKVRY
>NZ_CP017115.1|WP_000579564.1|1185560_1187555_+|serine/threonine-protein-kinase-Stk1
MIGKIINERYKIVDKLGGGGMSTVYLAEDTILNIKVAIKAIFIPPREKEETLKRFEREVHNSSQLSHQNIVSMIDVDEEDDCYYLVMEYIEGPTLSEYIESHGPLSVDTAINFTNQILDGIKHAHDMRIVHRDIKPQNILIDSNKTLKIFDFGIAKALSETSLTQTNHVLGTVQYFSPEQAKGEATDECTDIYSIGIVLYEMLVGEPPFNGETAVSIAIKHIQDSVPNVTTDVRKDIPQSLSNVILRATEKDKANRYKTIQEMKDDLSSVLHENRANEDVYELDKMKTIAVPLKKEDLAKHISEHKSNQPKRETTQVPIVNGPAHHQQFQKPEGTVYEPKPKKKSTRKIVLLSLIFSLLMIALVSFVAMAMFGNKYEETPDVIGKSVKEAEQIFNKNNLKLGKISRSYSDKYPENEIIKTTPNTGERVERGDSVDVVISKGPEKVKMPNVIGLPKEEALQKLKSLGLKDVTIEKVYNNQAPKGYIANQSVTANTEIAIHDSNIKLYESLGIKQVYVEDFEHKSFSKAKKALEEKGFKVESKEEYSDDIDEGDVISQSPKGKSVDEGSTISFVVSKGKKSDSSDVKTTTESVDVPYTGKNDKSQKVKVYIKDKDNDGSTEKGSFDITSDQRIDIPLRIEKGKTASYIVKVDGKTVAEKEVSYDDV
>NZ_CP017115.1|WP_000888498.1|1184820_1185564_+|protein-serine/threonine-phosphatase-Stp1
MLEAQFFTDTGQHRDKNEDAGGIFYNRTNQQLLVLCDGMGGHKAGEVASKFVTDELKSRFEAENLIEEHQAENWLRNNIKDINFQLYHYAQENAEYKGMGTTCVCALVFEKSVVIANVGDSRAYVINSRQIEQITSDHSFVNHLVLTGQITPEEAFTHPQRNIITKVMGTDKRVSPDLFIKRLNFYDYLLLNSDGLTDYVKDNEIKRLLVKEGTIEDHGDQLMQLALDNHSKDNVTFILAAIEGDKV
>NZ_CP017115.1|WP_000626905.1|1183719_1184814_+|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN
MITAEKKKKNKFLPNFDKQSIYSLRFDEMQNWLVEQGQQKFRAKQIFEWLYQKRVDSIDEMTNLSKDLRQLLKDNFTVTTLTTVVKQESKDGTIKFLYELQDGYTIETVLMRHDYGNSVCVTTQVGCRIGCTFCASTLGGLKRNLEAGEIVSQVLTVQKALDATEERVSQIVIMGIGEPFENYDEMMDFLRIVNDDNSLNIGARHITVSTSGIIPRIYDFADEDIQINFAVSLHAAKDEVRSRLMPINRAYNVEKLIEAIQYYQEKTNRRVTFEYGLFGGVNDQLEHARELAHLIKGLNCHVNLIPVNHVPERNYVKTAKNDIFKFEKELKRLGINATIRREQGSDIDAACGQLRAKERQVETR
>NZ_CP017115.1|WP_000572223.1|1182409_1183717_+|16S-rRNA-(cytosine(967)-C(5))-methyltransferase-RsmB
MIENVRSLAFDTIQDILNEGAYSNLRINEVLSENELNAMDKALFTEIVYGTVKRKFTLDFYLKPFVKTKIKAWVRQLLWMSIYQYVYLDKVPNHAIINEAVEIAKERGGYHNGNVVNGILRTMMRSDLPDFNEIADPKKRMAIEYSMPKWIIDHWATHYGLEKTETILQSFLETTSTTVRANLTRASLDDIIEKLQDEGYDVEKDHDLPYCLHIGGQPIIHSRSFKDGFVSIQDKSSMFVAHIMNVDRHDHVLDACSAPGGKACHIAEVLMPEGQVDASDIHDHKIDLINFNIKKLRLTNIKAFQHDATKPYDKTYDKILVDAPCSGLGVMRHKPEIKYTQSKQHIESLVELQLEILENVKNNVKIGGEIIYSTCTIEQLENENVIYTFLKNNKNFEFEPFQHPITGELVKTLQIMPQDFNSDGFFITKIKRKDN
>NZ_CP017115.1|WP_000426914.1|1199019_1199253_+|acyl-carrier-protein
MENFDKVKDIIVDRLGVDADKVTEDASFKDDLGADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKFINSLEK
>NZ_CP017115.1|WP_157665723.1|1204513_1204597_+|hypothetical-protein
MTNKQRNYLELFYLEDYSLSESQILLM
>NZ_CP017115.1|WP_000915244.1|1209207_1211814_-|YfhO-family-protein
MLKKWLNSNVKQFFVITFISVILTLILFSTHIYDYIVNGTVFSGAGDGFRQMMPFQMYLYEHLSSFSSLYDASFGLGGDYMKGLSYYYSLSPLMWLNFLFIKIGETVGIFNPTTIHFWPTNQLIMAMIRAIITFVVTFYLFKILHFKRSTNMIATILYGMSTVVIYFNFTWSFYGSLLYLLPLSILGLERYFQQRKIGIFIVAIALTLFSNFYFSYYQAIIIGCYYLYRLIFTYKYDIVSRTQKLICVISATVLSVLSSVFGLFTGISAFLENDRKQNPNVDIPFLTPLDYHYFFFSDGFYITISILTIVALLSFKLYRFYFYRLFAIVTWLLFIGSLSQYFDSAFNGFSFPERRWVYILALSSSALCGLFIQHLSTLNMKYYLIRTIPVSIIALLYVLLSPTHPLALIVGIILLMVLAVILKFSLWRYKKLTVAILVLIVMIQQIVILDNNKNMAIKPYQQSLSTLKQHDYHSNYVNQLIKKINQNATGPFNRIDYMSDYALNSPFIYHYNGISLYSSIFNGDILKYYDKTLQINMPIDKNSTYRLLGNRQNLLSLWNVNDRIRVNHDDNLPYGFKIKSEHKDNKVRWIHSKNTIHYPSAHITNKVFSNKELKSPLDKEQAMLQGIVSNKTKDVNTHFKANKNLLSDSTIKLNSAAWQSPTKHLLQVKQNNGGLTVQLPKSVSNQFKDLYFEMDLELLSPDKAHDVKVNEYTQERNKLTYKYRRFVTPVTIRIKASDRIRLSLPKGKYRVNLKGIYGEDYTTLKDASNSLEAVKVSKTKQGYTITKNKNSSGYIVLPTAYNQGMKATSGDQSLKVEQVNGVMTGIKAPKNITKIQLSYAPPYYYLLITITIFGIICSIIFTRWARQK
>NZ_CP017115.1|WP_000236715.1|1212214_1213099_+|ribosome-biogenesis-GTPase-YlqF
MVIQWYPGHMAKAKREVSEQLKKVDVVFELVDARIPYSSRNPMIDEVINQKPRVVILNKKDMSNLNEMSKWEQFFIDKGYYPVSVDAKHGKNLKKVEAAAIKATAEKFEREKAKGLKPRAIRAMIVGIPNVGKSTLINKLAKRSIAQTGNKPGVTKQQQWIKVGNALQLLDTPGILWPKFEDEEVGKKLSLTGAIKDSIVHLDEVAIYGLNFLIQHDLARLKSHYNIEVPEDAEIIAWFDAIGKKRGLIRRGNEIDYEAVIELIIYDIRNAKIGNYCFDIFKDMTEELANDANN
>NZ_CP017115.1|WP_157665722.1|1213082_1213781_+|ribonuclease-HII
MTLTIKEVKQLINAVNTIEELENHECFLDERKGVQNAIARRRKALEKEQALKEKYVEMTYFENEILKEHPNAIICGIDEVGRGPLAGPVVACATILNSNHNYLGLDDSKKVPVTKRLELNEALKNEVTAFAYGIATAEEIDEFNIYKATQIAMQRAIDGLSVQPTHLLIDAMTLDNALPQVSLIKGDARSVSIAAASIMAKVFRDDYMTQLSKDYPEYGFEKTRVTVPNNIY
>NZ_CP017115.1|WP_001020801.1|1213957_1215124_+|ADP-forming-succinate--CoA-ligase-subunit-beta
MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKELNSDVYVVKAQIHAGGRGKAGGVKIAKSLSEVETYAKELLGKTLVTHQTGPEGKEIKRLYIEEGCAIQKEYYVGFVIDRATDQVTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQARRIAFNINIPKESVNKAAKFLLALYNVFIEKDCSIVEINPLVTTADGDVLALDAKINFDDNALFRHKDVVELRDLEEEDPKEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLDAGGSATREKVTEAFKIILGDENVKGIFVNIFGGIMKCDVIAEGIVEAVKEVDLTLPLVVRLEGTNVELGKKILKDSGLAIEPAATMAEGAQKIVKLVKEA
>NZ_CP017115.1|WP_000110251.1|1215145_1216054_+|succinate--CoA-ligase-subunit-alpha
MSVFIDKNTKVMVQGITGSTALFHTKQMLDYGTKIVAGVTPGKGGQVVEGVPVFNTVEEAKNETGATVSVIYVPAPFAADSILEAADADLDMVICITEHIPVLDMVKVKRYLQGRKTRLVGPNCPGVITADECKIGIMPGYIHKKGHVGVVSRSGTLTYEAVHQLTEEGIGQTTAVGIGGDPVNGTNFIDVLKAFNEDDETKAVVMIGEIGGTAEEEAAEWIKANMTKPVVGFIGGQTAPPGKRMGHAGAIISGGKGTAEEKIKTLNSCGVKTAATPSEIGSTLIEAAKEAGIYEALLTVNK
>NZ_CP017115.1|WP_001041666.1|1216280_1217399_+|LysM-peptidoglycan-binding-domain-containing-protein
MNKQQSKVRYSIRKVSIGILSISIGMFLALGMSNKAYADEIDKSKDFTRGYEQNVFAKSELNANKNTTKDKIKNEGAVKTSDTSLKLDNKSAISNGNEINQDIKISNTPKNSSQGNNLVINNNEPTKEIKIANLEAQNSNQKKTNKVTNNYFGYYSFREAPKTQIYTVKKGDTLSAIALKYKTTVSNIQNTNNIANPNLIFIGQKLKVPMTPLVEPKPKTVSSNNKSNSNSSTLNYLKTLENRGWDFDGSYGWQCFDLVNVYWNHLYGHGLKGYGAKDIPYANNFNSEAKIYHNTPTFKAEPGDLVVFSGRFGGGYGHTAIVLNGDYDGKLMKFQSLDQNWNNGGWRKAEVAHKVVHNYENDMIFIRPFKKA
>NZ_CP017115.1|WP_000672867.1|1217426_1218671_+|FemA/FemB-family-glycyltransferase-FmhC
MKFSTLSEEEFTNYTKKHFKHYTQSIELYNYRNKINHEAHIVGVKNDKNEVIAACLLTEARIFKFYKYFYSHRGPLLDYFDAKLVCYFFKELSKFIYKNRGVFILVDPYLIENLRDANGRIIKNYNNSVIVKMLGKIGYLHQGYTTGYSNKSQIRWISVLDLKDKDENQLLKEMEYQTRRNIKKTIEIGVKVEDLSIEETNRFYKLFQMAEEKHGFHFMNEDYFKRMQEIYKDKAMLKIACINLNEYQDKLKIQLLKIENEMMTVNRALNENPNSKKNKSKLNQLNMQLSSINNRISKTEELIFEDGPVLDLAAALFICTDDEVYYLSSGSNPKYNQYMGAYHLQWHMIKYAKSHNINRYNFYGITGVFSNEADDFGVQQFKKGFNAHVEELIGDFIKPVRPILYKFAKLIYKV
>NZ_CP017115.1|WP_000593192.1|1218843_1219716_+|DNA-protecting-protein-DprA
MIKLFLLKLYWAHFSTKQIHQFLMAYPNVIKEEGRKKDSYLCEWVNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYITYMDSEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQIALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHITIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI

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Crispr_ID: NZ_CP017115_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017115_5

1209049-1209134

Orphan

Consensus_repeat	Method
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP017115_5

>merge|NZ_CP017115|5|1209049-1209134|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACATAGAAGCTGGCGGAAAGTCAGCTTACAATAATGTGCAAGTTGG

>NZ_CP017115|5|5|1209049-1209134|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CGGGGCCCCAACATAGAAGCTGGCGG
AAAGTCAGCTTACAATAATGTGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017115.1\|WP_000426914.1\|1199019_1199253_+\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|179197
NZ_CP017115.1\|WP_000167269.1\|1197915_1198650_+\|3-oxoacyl-[acyl-carrier-protein]-reductase	unknown	unknown	gnl\|CDD\|235500
NZ_CP017115.1\|WP_157665722.1\|1213082_1213781_+\|ribonuclease-HII	unknown	unknown	gnl\|CDD\|260003
NZ_CP017115.1\|WP_000517908.1\|1190328_1190517_-\|50S-ribosomal-protein-L28	unknown	unknown	gnl\|CDD\|234736
NZ_CP017115.1\|WP_000915244.1\|1209207_1211814_-\|YfhO-family-protein	unknown	unknown	gnl\|CDD\|226888
NZ_CP017115.1\|WP_001020801.1\|1213957_1215124_+\|ADP-forming-succinate--CoA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234813
NZ_CP017115.1\|WP_000579564.1\|1185560_1187555_+\|serine/threonine-protein-kinase-Stk1	unknown	unknown	gnl\|CDD\|270916
NZ_CP017115.1\|WP_000171418.1\|1190958_1191333_+\|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl\|CDD\|224221
NZ_CP017115.1\|WP_001557331.1\|1219889_1221965_+\|type-I-DNA-topoisomerase	unknown	unknown	gnl\|CDD\|235516
NZ_CP017115.1\|WP_000672867.1\|1217426_1218671_+\|FemA/FemB-family-glycyltransferase-FmhC	unknown	unknown	gnl\|CDD\|367067
NZ_CP017115.1\|WP_157665723.1\|1204513_1204597_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234647
NZ_CP017115.1\|WP_000888498.1\|1184820_1185564_+\|protein-serine/threonine-phosphatase-Stp1	unknown	unknown	gnl\|CDD\|223704
NZ_CP017115.1\|WP_000239748.1\|1196020_1197007_+\|phosphate-acyltransferase-PlsX	unknown	unknown	gnl\|CDD\|235414
NZ_CP017115.1\|WP_088607369.1\|1187782_1188658_+\|ribosome-small-subunit-dependent-GTPase-A	unknown	unknown	gnl\|CDD\|224084
NZ_CP017115.1\|WP_000195254.1\|1222120_1223428_+\|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO	unknown	unknown	gnl\|CDD\|235416
NZ_CP017115.1\|WP_000236715.1\|1212214_1213099_+\|ribosome-biogenesis-GTPase-YlqF	unknown	unknown	gnl\|CDD\|236570
NZ_CP017115.1\|WP_001041666.1\|1216280_1217399_+\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|366664
NZ_CP017115.1\|WP_000593192.1\|1218843_1219716_+\|DNA-protecting-protein-DprA	unknown	unknown	gnl\|CDD\|223829
NZ_CP017115.1\|WP_001548538.1\|1195443_1196016_+\|transcription-factor-FapR	unknown	unknown	gnl\|CDD\|179847
NZ_CP017115.1\|WP_000110251.1\|1215145_1216054_+\|succinate--CoA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|180194

Protein	Function_ID	Function_description	E-value
NZ_CP017115.1\|WP_000426914.1\|1199019_1199253_+\|acyl-carrier-protein	gnl\|CDD\|179197	PRK00982, acpP, acyl carrier protein; Provisional.	5.23888e-31
NZ_CP017115.1\|WP_000167269.1\|1197915_1198650_+\|3-oxoacyl-[acyl-carrier-protein]-reductase	gnl\|CDD\|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	3.68137e-140
NZ_CP017115.1\|WP_157665722.1\|1213082_1213781_+\|ribonuclease-HII	gnl\|CDD\|260003	cd07182, RNase_HII_bacteria_HII_like, Bacterial Ribonuclease HII-like. This family includes mostly bacterial type 2 RNases H, with some eukaryotic members. Bacterial RNase HII has a role in primer removal based on its involvement in ribonucleotide-specific catalytic activity in the presence of RNA/DNA hybrid substrates. Several bacteria, such as Bacillus subtilis, have two different type II RNases H, RNases HII and HIII; double deletion of these leads to cellular lethality. It appears that type I and type II RNases H also have overlapping functions in cells, as over-expression of Escherichia coli RNase HII can complement an RNase HI deletion phenotype. In Leishmania mitochondria, of the four distinct RNase H genes (H1, HIIA, HIIB, HIIC), HIIC is essential for the survival of the parasite and thus can be a potential target for anti-leishmanial chemotherapy. Ribonuclease H (RNase H) is classified into two families, type I (prokaryotic RNase HI, eukaryotic RNase H1 and viral RNase H) and type II (prokaryotic RNase HII and HIII, and eukaryotic RNase H2). RNase H endonucleolytically hydrolyzes an RNA strand when it is annealed to a complementary DNA strand in the presence of divalent cations, in DNA replication and repair.	1.74257e-78
NZ_CP017115.1\|WP_000517908.1\|1190328_1190517_-\|50S-ribosomal-protein-L28	gnl\|CDD\|234736	PRK00359, rpmB, 50S ribosomal protein L28; Reviewed.	1.3072e-18
NZ_CP017115.1\|WP_000915244.1\|1209207_1211814_-\|YfhO-family-protein	gnl\|CDD\|226888	COG4485, COG4485, Predicted membrane protein [Function unknown].	0
NZ_CP017115.1\|WP_001020801.1\|1213957_1215124_+\|ADP-forming-succinate--CoA-ligase-subunit-beta	gnl\|CDD\|234813	PRK00696, sucC, ADP-forming succinate--CoA ligase subunit beta.	0
NZ_CP017115.1\|WP_000579564.1\|1185560_1187555_+\|serine/threonine-protein-kinase-Stk1	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.57684e-117
NZ_CP017115.1\|WP_000171418.1\|1190958_1191333_+\|Asp23/Gls24-family-envelope-stress-response-protein	gnl\|CDD\|224221	COG1302, COG1302, Uncharacterized protein conserved in bacteria [Function unknown].	4.1554e-37
NZ_CP017115.1\|WP_001557331.1\|1219889_1221965_+\|type-I-DNA-topoisomerase	gnl\|CDD\|235516	PRK05582, PRK05582, type I DNA topoisomerase.	0
NZ_CP017115.1\|WP_000672867.1\|1217426_1218671_+\|FemA/FemB-family-glycyltransferase-FmhC	gnl\|CDD\|367067	pfam02388, FemAB, FemAB family. The femAB operon codes for two nearly identical approximately 50-kDa proteins involved in the formation of the Staphylococcal pentaglycine interpeptide bridge in peptidoglycan. These proteins are also considered as a factor influencing the level of methicillin resistance.	0
NZ_CP017115.1\|WP_157665723.1\|1204513_1204597_+\|hypothetical-protein	gnl\|CDD\|234647	PRK00118, PRK00118, putative DNA-binding protein; Validated.	0.000177219
NZ_CP017115.1\|WP_000888498.1\|1184820_1185564_+\|protein-serine/threonine-phosphatase-Stp1	gnl\|CDD\|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	7.74558e-90
NZ_CP017115.1\|WP_000239748.1\|1196020_1197007_+\|phosphate-acyltransferase-PlsX	gnl\|CDD\|235414	PRK05331, PRK05331, phosphate acyltransferase PlsX.	6.1953e-178
NZ_CP017115.1\|WP_088607369.1\|1187782_1188658_+\|ribosome-small-subunit-dependent-GTPase-A	gnl\|CDD\|224084	COG1162, COG1162, Predicted GTPases [General function prediction only].	8.53811e-128
NZ_CP017115.1\|WP_000195254.1\|1222120_1223428_+\|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO	gnl\|CDD\|235416	PRK05335, PRK05335, tRNA (uracil-5-)-methyltransferase Gid; Reviewed.	0
NZ_CP017115.1\|WP_000236715.1\|1212214_1213099_+\|ribosome-biogenesis-GTPase-YlqF	gnl\|CDD\|236570	PRK09563, rbgA, GTPase YlqF; Reviewed.	2.28339e-159
NZ_CP017115.1\|WP_001041666.1\|1216280_1217399_+\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|366664	pfam01476, LysM, LysM domain. The LysM (lysin motif) domain is about 40 residues long. It is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. The structure of this domain is known.	1.45655e-14
NZ_CP017115.1\|WP_000593192.1\|1218843_1219716_+\|DNA-protecting-protein-DprA	gnl\|CDD\|223829	COG0758, Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion].	7.99896e-103
NZ_CP017115.1\|WP_001548538.1\|1195443_1196016_+\|transcription-factor-FapR	gnl\|CDD\|179847	PRK04424, PRK04424, transcription factor FapR.	2.37773e-98
NZ_CP017115.1\|WP_000110251.1\|1215145_1216054_+\|succinate--CoA-ligase-subunit-alpha	gnl\|CDD\|180194	PRK05678, PRK05678, succinyl-CoA synthetase subunit alpha; Validated.	0

>NZ_CP017115.1|WP_157665723.1|1204513_1204597_+|hypothetical-protein
MTNKQRNYLELFYLEDYSLSESQILLM
>NZ_CP017115.1|WP_000426914.1|1199019_1199253_+|acyl-carrier-protein
MENFDKVKDIIVDRLGVDADKVTEDASFKDDLGADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKFINSLEK
>NZ_CP017115.1|WP_000167269.1|1197915_1198650_+|3-oxoacyl-[acyl-carrier-protein]-reductase
MTKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVAPGFIVSDMTDALSDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQTIHVNGGMYM
>NZ_CP017115.1|WP_000239748.1|1196020_1197007_+|phosphate-acyltransferase-PlsX
MVKLAIDMMGGDNAPDIVLEAVQKAVEDFKDLEIILFGDEKKYNLNHERIEFRHCSEKIEMEDEPVRAIKRKKDSSMVKMAEAVKSGEADGCVSAGNTGALMSAGLFIVGRIKGVARPALVVTLPTIDGKGFVFLDVGANADAKPEHLLQYAQLGDIYAQKIRGIDNPKISLLNIGTEPAKGNSLTKKSYELLNQDHSLNFVGNIEAKTLMDGDTDVVVTDGYTGNMVLKNLEGTAKSIGKMLKDTIMSSTKNKLAGAILKKDLAEFAKKMDYSEYGGSVLLGLEGTVVKAHGSSNAKAFYSAIRQAKIAGEQNIVQTMKETVGESNE
>NZ_CP017115.1|WP_001548538.1|1195443_1196016_+|transcription-factor-FapR
MRGETLKLKKDKRREAIRQQIDSNPFITDHELSDLFQVSIQTIRLDRTYLNIPELRKRIKLVAEKNYDQISSIEEQEFIGDLIQVNPNVKAQSILDITSDSVFHKTGIARGHVLFAQANSLCVALIKQPTVLTHESSIQFIEKVKLNDTVRAEARVVNQTAKHYYVEVKSYVKHTLVFKGNFKMFYDKRG
>NZ_CP017115.1|WP_000171418.1|1190958_1191333_+|Asp23/Gls24-family-envelope-stress-response-protein
MTLEISNDYGKIDISNEVIASVVGGKAVECYGIVGMASRQQVRDGIAEILGHENYAKGIKVTENNGVVDIDMYIIVSYGVKISEVANNVQSTVKYTLEKSLNVSVNSINIYVQGVRVNNTGKKA
>NZ_CP017115.1|WP_000517908.1|1190328_1190517_-|50S-ribosomal-protein-L28
MGKQCFVTGRKASTGNRRSHALNSTKRRWNANLQKVRILVDGKPKKVWVSARALKSGKVTRV
>NZ_CP017115.1|WP_088607369.1|1187782_1188658_+|ribosome-small-subunit-dependent-GTPase-A
MKTGRIVKSISGVYQVDVNGERFNTKPRGLFRKKKFSPVVGDIVEFEVQNINEGYIHQVFERENELKRPPVSNIDTLVIVMSAVEPNFSTQLLDRFLVIAHSYQLNARVLVTKKDKTPIEKQFEINELLKIYENIGYETEFIGNDDDRKKIVEAWPAGLIVLSGQSGVGKSTFLNHYRPELNLETNDISKSLNRGKHTTRHVELFERQNGYIADTPGFSALDFDHIDKDEIKDYFLELNRYGETCKFRNCNHIKEPNCNVKHQLEIGNIAQFRYDHYLQLFNEISNRKVRY
>NZ_CP017115.1|WP_000579564.1|1185560_1187555_+|serine/threonine-protein-kinase-Stk1
MIGKIINERYKIVDKLGGGGMSTVYLAEDTILNIKVAIKAIFIPPREKEETLKRFEREVHNSSQLSHQNIVSMIDVDEEDDCYYLVMEYIEGPTLSEYIESHGPLSVDTAINFTNQILDGIKHAHDMRIVHRDIKPQNILIDSNKTLKIFDFGIAKALSETSLTQTNHVLGTVQYFSPEQAKGEATDECTDIYSIGIVLYEMLVGEPPFNGETAVSIAIKHIQDSVPNVTTDVRKDIPQSLSNVILRATEKDKANRYKTIQEMKDDLSSVLHENRANEDVYELDKMKTIAVPLKKEDLAKHISEHKSNQPKRETTQVPIVNGPAHHQQFQKPEGTVYEPKPKKKSTRKIVLLSLIFSLLMIALVSFVAMAMFGNKYEETPDVIGKSVKEAEQIFNKNNLKLGKISRSYSDKYPENEIIKTTPNTGERVERGDSVDVVISKGPEKVKMPNVIGLPKEEALQKLKSLGLKDVTIEKVYNNQAPKGYIANQSVTANTEIAIHDSNIKLYESLGIKQVYVEDFEHKSFSKAKKALEEKGFKVESKEEYSDDIDEGDVISQSPKGKSVDEGSTISFVVSKGKKSDSSDVKTTTESVDVPYTGKNDKSQKVKVYIKDKDNDGSTEKGSFDITSDQRIDIPLRIEKGKTASYIVKVDGKTVAEKEVSYDDV
>NZ_CP017115.1|WP_000888498.1|1184820_1185564_+|protein-serine/threonine-phosphatase-Stp1
MLEAQFFTDTGQHRDKNEDAGGIFYNRTNQQLLVLCDGMGGHKAGEVASKFVTDELKSRFEAENLIEEHQAENWLRNNIKDINFQLYHYAQENAEYKGMGTTCVCALVFEKSVVIANVGDSRAYVINSRQIEQITSDHSFVNHLVLTGQITPEEAFTHPQRNIITKVMGTDKRVSPDLFIKRLNFYDYLLLNSDGLTDYVKDNEIKRLLVKEGTIEDHGDQLMQLALDNHSKDNVTFILAAIEGDKV
>NZ_CP017115.1|WP_000915244.1|1209207_1211814_-|YfhO-family-protein
MLKKWLNSNVKQFFVITFISVILTLILFSTHIYDYIVNGTVFSGAGDGFRQMMPFQMYLYEHLSSFSSLYDASFGLGGDYMKGLSYYYSLSPLMWLNFLFIKIGETVGIFNPTTIHFWPTNQLIMAMIRAIITFVVTFYLFKILHFKRSTNMIATILYGMSTVVIYFNFTWSFYGSLLYLLPLSILGLERYFQQRKIGIFIVAIALTLFSNFYFSYYQAIIIGCYYLYRLIFTYKYDIVSRTQKLICVISATVLSVLSSVFGLFTGISAFLENDRKQNPNVDIPFLTPLDYHYFFFSDGFYITISILTIVALLSFKLYRFYFYRLFAIVTWLLFIGSLSQYFDSAFNGFSFPERRWVYILALSSSALCGLFIQHLSTLNMKYYLIRTIPVSIIALLYVLLSPTHPLALIVGIILLMVLAVILKFSLWRYKKLTVAILVLIVMIQQIVILDNNKNMAIKPYQQSLSTLKQHDYHSNYVNQLIKKINQNATGPFNRIDYMSDYALNSPFIYHYNGISLYSSIFNGDILKYYDKTLQINMPIDKNSTYRLLGNRQNLLSLWNVNDRIRVNHDDNLPYGFKIKSEHKDNKVRWIHSKNTIHYPSAHITNKVFSNKELKSPLDKEQAMLQGIVSNKTKDVNTHFKANKNLLSDSTIKLNSAAWQSPTKHLLQVKQNNGGLTVQLPKSVSNQFKDLYFEMDLELLSPDKAHDVKVNEYTQERNKLTYKYRRFVTPVTIRIKASDRIRLSLPKGKYRVNLKGIYGEDYTTLKDASNSLEAVKVSKTKQGYTITKNKNSSGYIVLPTAYNQGMKATSGDQSLKVEQVNGVMTGIKAPKNITKIQLSYAPPYYYLLITITIFGIICSIIFTRWARQK
>NZ_CP017115.1|WP_000236715.1|1212214_1213099_+|ribosome-biogenesis-GTPase-YlqF
MVIQWYPGHMAKAKREVSEQLKKVDVVFELVDARIPYSSRNPMIDEVINQKPRVVILNKKDMSNLNEMSKWEQFFIDKGYYPVSVDAKHGKNLKKVEAAAIKATAEKFEREKAKGLKPRAIRAMIVGIPNVGKSTLINKLAKRSIAQTGNKPGVTKQQQWIKVGNALQLLDTPGILWPKFEDEEVGKKLSLTGAIKDSIVHLDEVAIYGLNFLIQHDLARLKSHYNIEVPEDAEIIAWFDAIGKKRGLIRRGNEIDYEAVIELIIYDIRNAKIGNYCFDIFKDMTEELANDANN
>NZ_CP017115.1|WP_157665722.1|1213082_1213781_+|ribonuclease-HII
MTLTIKEVKQLINAVNTIEELENHECFLDERKGVQNAIARRRKALEKEQALKEKYVEMTYFENEILKEHPNAIICGIDEVGRGPLAGPVVACATILNSNHNYLGLDDSKKVPVTKRLELNEALKNEVTAFAYGIATAEEIDEFNIYKATQIAMQRAIDGLSVQPTHLLIDAMTLDNALPQVSLIKGDARSVSIAAASIMAKVFRDDYMTQLSKDYPEYGFEKTRVTVPNNIY
>NZ_CP017115.1|WP_001020801.1|1213957_1215124_+|ADP-forming-succinate--CoA-ligase-subunit-beta
MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKELNSDVYVVKAQIHAGGRGKAGGVKIAKSLSEVETYAKELLGKTLVTHQTGPEGKEIKRLYIEEGCAIQKEYYVGFVIDRATDQVTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQARRIAFNINIPKESVNKAAKFLLALYNVFIEKDCSIVEINPLVTTADGDVLALDAKINFDDNALFRHKDVVELRDLEEEDPKEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLDAGGSATREKVTEAFKIILGDENVKGIFVNIFGGIMKCDVIAEGIVEAVKEVDLTLPLVVRLEGTNVELGKKILKDSGLAIEPAATMAEGAQKIVKLVKEA
>NZ_CP017115.1|WP_000110251.1|1215145_1216054_+|succinate--CoA-ligase-subunit-alpha
MSVFIDKNTKVMVQGITGSTALFHTKQMLDYGTKIVAGVTPGKGGQVVEGVPVFNTVEEAKNETGATVSVIYVPAPFAADSILEAADADLDMVICITEHIPVLDMVKVKRYLQGRKTRLVGPNCPGVITADECKIGIMPGYIHKKGHVGVVSRSGTLTYEAVHQLTEEGIGQTTAVGIGGDPVNGTNFIDVLKAFNEDDETKAVVMIGEIGGTAEEEAAEWIKANMTKPVVGFIGGQTAPPGKRMGHAGAIISGGKGTAEEKIKTLNSCGVKTAATPSEIGSTLIEAAKEAGIYEALLTVNK
>NZ_CP017115.1|WP_001041666.1|1216280_1217399_+|LysM-peptidoglycan-binding-domain-containing-protein
MNKQQSKVRYSIRKVSIGILSISIGMFLALGMSNKAYADEIDKSKDFTRGYEQNVFAKSELNANKNTTKDKIKNEGAVKTSDTSLKLDNKSAISNGNEINQDIKISNTPKNSSQGNNLVINNNEPTKEIKIANLEAQNSNQKKTNKVTNNYFGYYSFREAPKTQIYTVKKGDTLSAIALKYKTTVSNIQNTNNIANPNLIFIGQKLKVPMTPLVEPKPKTVSSNNKSNSNSSTLNYLKTLENRGWDFDGSYGWQCFDLVNVYWNHLYGHGLKGYGAKDIPYANNFNSEAKIYHNTPTFKAEPGDLVVFSGRFGGGYGHTAIVLNGDYDGKLMKFQSLDQNWNNGGWRKAEVAHKVVHNYENDMIFIRPFKKA
>NZ_CP017115.1|WP_000672867.1|1217426_1218671_+|FemA/FemB-family-glycyltransferase-FmhC
MKFSTLSEEEFTNYTKKHFKHYTQSIELYNYRNKINHEAHIVGVKNDKNEVIAACLLTEARIFKFYKYFYSHRGPLLDYFDAKLVCYFFKELSKFIYKNRGVFILVDPYLIENLRDANGRIIKNYNNSVIVKMLGKIGYLHQGYTTGYSNKSQIRWISVLDLKDKDENQLLKEMEYQTRRNIKKTIEIGVKVEDLSIEETNRFYKLFQMAEEKHGFHFMNEDYFKRMQEIYKDKAMLKIACINLNEYQDKLKIQLLKIENEMMTVNRALNENPNSKKNKSKLNQLNMQLSSINNRISKTEELIFEDGPVLDLAAALFICTDDEVYYLSSGSNPKYNQYMGAYHLQWHMIKYAKSHNINRYNFYGITGVFSNEADDFGVQQFKKGFNAHVEELIGDFIKPVRPILYKFAKLIYKV
>NZ_CP017115.1|WP_000593192.1|1218843_1219716_+|DNA-protecting-protein-DprA
MIKLFLLKLYWAHFSTKQIHQFLMAYPNVIKEEGRKKDSYLCEWVNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYITYMDSEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQIALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHITIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI
>NZ_CP017115.1|WP_001557331.1|1219889_1221965_+|type-I-DNA-topoisomerase
MTLADNLVIVESPAKAKTIEKYLGKKYKVIASMGHVRDLPRSQMGVDTEDNYEPKYITIRGKGPVVKELKKHAKKAKNVFLASDPDREGEAIAWHLSKILELEDSKENRVVFNEITKDAVKESFKNPREIEMNLVDAQQARRILDRLVGYNISPVLWKKVKKGLSAGRVQSVALRLVIDRENEIRNFKPEEYWTIEGEFRYKKSKFNAKFLHYKNKPFKLKTKKDVEKITAALDGDQFEITNVTKKEKTRNPANPFTTSTLQQEAARKLNFKARKTMMVAQQLYEGIDLKKQGTIGLITYMRTDSTRISDTAKAEAKQYITDKYGESYTSKRKASGKQGDQDAHEAIRPSSTMRTPDDMKSFLTKDQYRLYKLIWERFVASQMAPAILDTVSLDITQGDIKFRANGQTIKFKGFMTLYVETKDDSDSEKENKLPKLEQGDKVTATQIEPAQHYTQPPPRYTEARLVKTLEELKIGRPSTYAPTIDTIQKRNYVKLESKRFVPTELGEIVHEQVKEYFPEIIDVEFTVNMETLLDKIAEGDITWRKVIDGFFSSFKQDVERAEEEMEKIEIKDEPAGEDCEVCGSPMVIKMGRYGKFMACSNFPDCRNTKAIVKSIGVKCPKCNDGDVVERKSKKNRVFYGCSKYPECDFISWDKPIGRDCPKCNQYLVENKKGKTTQVICSNCDYKEAAQK
>NZ_CP017115.1|WP_000195254.1|1222120_1223428_+|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO
MTQTVNVIGAGLAGSEAAYQLAERGIKVNLIEMRPVKQTPAHHTDKFAELVCSNSLRGNALTNGVGVLKEEMRRLNSIIIEAADKARVPAGGALAVDRHDFSGYITETLKNHENITVINEEINAIPDGYTIIATGPLTTETLAQEIVDITGKDQLYFYDAAAPIIEKESIDMDKVYLKSRYDKGEAAYLNCPMTEDEFNRFYDAVLEAEVAPVNSFEKEKYFEGCMPFEVMAERGRKTLLFGPMKPVGLEDPKTGKRPYAVVQLRQDDAAGTLYNIVGFQTHLKWGAQKEVIKLIPGLENVDIVRYGVMHRNTFINSPDVLNEKYELISQPNIQFAGQMTGVEGYVESAASGLVAGINLAHKILGKGEVVFPRETMIGSMAYYISHAKNNKNFQPMNANFGLLPSLETRIKDKKERYEAQANRALDYLENFKKTL

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Crispr_ID: NZ_CP017115_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017115_6

1677776-1677861

Orphan

Consensus_repeat	Method
TCTGTGTTGGGGCCCCATCCCCAACTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP017115_6

>merge|NZ_CP017115|6|1677776-1677861|CRISPRCasFinder
TCTGTGTTGGGGCCCCATCCCCAACTTGCACATTATTGAAATCTGACTTTTGGTCAGCTTCTGTGTTGGGGCCCCGTCCCCAACTT

>NZ_CP017115|6|6|1677776-1677861|CRISPRCasFinder
TCTGTGTTGGGGCCCCATCCCCAACTT	GCACATTATTGAAATCTGACTTTTGGTCAGCT
TCTGTGTTGGGGCCCCGTCCCCAACTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017115.1\|WP_000567030.1\|1676794_1677463_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NZ_CP017115.1\|WP_000137775.1\|1668415_1669339_-\|U32-family-peptidase	unknown	unknown	gnl\|CDD\|223896
NZ_CP017115.1\|WP_000734072.1\|1671342_1673973_-\|alanine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234701
NZ_CP017115.1\|WP_000044799.1\|1685510_1687277_-\|aspartate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234775
NZ_CP017115.1\|WP_001283312.1\|1674315_1676793_-\|ATP-dependent-RecD-like-DNA-helicase	unknown	unknown	gnl\|CDD\|273632
NZ_CP017115.1\|WP_000704122.1\|1682334_1682757_-\|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224870
NZ_CP017115.1\|WP_000102740.1\|1682841_1684116_+\|replication-associated-recombination-protein-A	unknown	unknown	gnl\|CDD\|237355
NZ_CP017115.1\|WP_000648617.1\|1666512_1667136_-\|uridine-kinase	unknown	unknown	gnl\|CDD\|235492
NZ_CP017115.1\|WP_000426912.1\|1671019_1671280_-\|IreB-family-regulatory-phosphoprotein	unknown	unknown	gnl\|CDD\|180108
NZ_CP017115.1\|WP_000342266.1\|1669341_1669980_-\|O-methyltransferase	unknown	unknown	gnl\|CDD\|226607
NZ_CP017115.1\|WP_000409158.1\|1679162_1680305_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
NZ_CP017115.1\|WP_000939059.1\|1670587_1671016_-\|Holliday-junction-resolvase-RuvX	unknown	unknown	gnl\|CDD\|223886
NZ_CP017115.1\|WP_000985895.1\|1680616_1681630_+\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274646
NZ_CP017115.1\|WP_000752909.1\|1682052_1682235_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_CP017115.1\|WP_000009238.1\|1681866_1682013_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_000134779.1\|1670264_1670573_-\|DUF1292-domain-containing-protein	unknown	unknown	gnl\|CDD\|184235
NZ_CP017115.1\|WP_000682646.1\|1684276_1685050_-\|tRNA-threonylcarbamoyladenosine-dehydratase	unknown	unknown	gnl\|CDD\|224100
NZ_CP017115.1\|WP_000848304.1\|1667135_1668404_-\|U32-family-peptidase	unknown	unknown	gnl\|CDD\|223896
NZ_CP017115.1\|WP_000066094.1\|1678043_1679162_-\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664
NZ_CP017115.1\|WP_001790559.1\|1685049_1685178_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP017115.1\|WP_000567030.1\|1676794_1677463_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	5.22121e-16
NZ_CP017115.1\|WP_000137775.1\|1668415_1669339_-\|U32-family-peptidase	gnl\|CDD\|223896	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones].	4.87045e-104
NZ_CP017115.1\|WP_000734072.1\|1671342_1673973_-\|alanine--tRNA-ligase	gnl\|CDD\|234701	PRK00252, alaS, alanyl-tRNA synthetase; Reviewed.	0
NZ_CP017115.1\|WP_000044799.1\|1685510_1687277_-\|aspartate--tRNA-ligase	gnl\|CDD\|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0
NZ_CP017115.1\|WP_001283312.1\|1674315_1676793_-\|ATP-dependent-RecD-like-DNA-helicase	gnl\|CDD\|273632	TIGR01448, recD_rel, helicase, putative, RecD/TraA family. This model describes a family similar to RecD, the exodeoxyribonuclease V alpha chain of TIGR01447. Members of this family, however, are not found in a context of RecB and RecC and are longer by about 200 amino acids at the amino end. Chlamydia muridarum has both a member of this family and a RecD. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP017115.1\|WP_000704122.1\|1682334_1682757_-\|Rrf2-family-transcriptional-regulator	gnl\|CDD\|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	5.58388e-46
NZ_CP017115.1\|WP_000648617.1\|1666512_1667136_-\|uridine-kinase	gnl\|CDD\|235492	PRK05480, PRK05480, uridine/cytidine kinase; Provisional.	5.13835e-138
NZ_CP017115.1\|WP_000426912.1\|1671019_1671280_-\|IreB-family-regulatory-phosphoprotein	gnl\|CDD\|180108	PRK05473, IreB-like, IreB family regulatory phosphoprotein. IreB (EF1202) was characterized in Enterococcus faecalis as a small protein, well-conserved in the Firmicutes. It belongs to a system that includes the Ser/Thr protein kinase IreK, and phosphatase IreP, undergoes phosphorylation on threonine residues, and is involved in regulating cephalosporin resistance. This family was previously named DUF965 by Pfam model pfam06135.	3.05024e-47
NZ_CP017115.1\|WP_000342266.1\|1669341_1669980_-\|O-methyltransferase	gnl\|CDD\|226607	COG4122, COG4122, Predicted O-methyltransferase [General function prediction only].	1.23148e-73
NZ_CP017115.1\|WP_000409158.1\|1679162_1680305_-\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	0
NZ_CP017115.1\|WP_000939059.1\|1670587_1671016_-\|Holliday-junction-resolvase-RuvX	gnl\|CDD\|223886	COG0816, COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) [DNA replication, recombination, and repair].	3.40149e-56
NZ_CP017115.1\|WP_000985895.1\|1680616_1681630_+\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|274646	TIGR03558, oxido_grp_1, luciferase family oxidoreductase, group 1. The Pfam domain family pfam00296 is named for luciferase-like monooxygenases, but the family also contains several coenzyme F420-dependent enzymes. This protein family represents a well-resolved clade within family pfam00296 and shows no restriction to coenzyme F420-positive species, unlike some other clades within pfam00296. [Unknown function, Enzymes of unknown specificity].	1.49102e-173
NZ_CP017115.1\|WP_000752909.1\|1682052_1682235_-\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	4.22501e-07
NZ_CP017115.1\|WP_000102740.1\|1682841_1684116_+\|replication-associated-recombination-protein-A	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NZ_CP017115.1\|WP_000134779.1\|1670264_1670573_-\|DUF1292-domain-containing-protein	gnl\|CDD\|184235	PRK13678, PRK13678, hypothetical protein; Provisional.	1.28539e-26
NZ_CP017115.1\|WP_000682646.1\|1684276_1685050_-\|tRNA-threonylcarbamoyladenosine-dehydratase	gnl\|CDD\|224100	COG1179, COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism].	1.59061e-126
NZ_CP017115.1\|WP_000848304.1\|1667135_1668404_-\|U32-family-peptidase	gnl\|CDD\|223896	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones].	5.98972e-149
NZ_CP017115.1\|WP_000066094.1\|1678043_1679162_-\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0

>NZ_CP017115.1|WP_000567030.1|1676794_1677463_-|tetratricopeptide-repeat-protein
MIDQQTIYQYIQNGKIEEALQALFGNIEENPTIIENYINAGIVLADANEIEKAERFFQKALTIDPKNGVVFYNLANVYYNQQRYQEAIKLYQQALQTEIEQVDCNYMIGMAFNQLESFKLALPYLMTAAELDKDKDAEVQFQYGLVLCQLEMFNEAITQLKHVLTIDKNHVDARYNLGLALFMKNEDIDEAITHFKEAVTIDPKHLLSQHALKTFTKMKEEE
>NZ_CP017115.1|WP_001283312.1|1674315_1676793_-|ATP-dependent-RecD-like-DNA-helicase
MSDPTLFDYSMIKGTVEAILFQNSDNFYTVLKVDTIETNEDFDTMPTVVGFLPNIVEGDVYTFKGQVVDHPRYGKQLKAETFEKEMPQTKEAIISYLSSDLFKGVGKKTAQNIVNTLGDNAINDILDDHSVLEKVSGLSKKKQKQIAEQISANQESEKIMIRLHDLGFGPKLSMAIYQFYLGDTLTILDRNPYQLIYDIKGIGFNKADQLARNIGIAYNDNERLKAALLYTLEEECIKQGHTYLPINVVIDLTVDVLNYQDEEVIEPEKLDEMLQYLNEEKRLIIDNEQVAIPSLYYSEIKSVQNLFRIKTHTNKLTEIEQSDLQMHIGEIEDANQVNYAASQKEALQTAINSKVMLLTGGPGTGKTTVIKGIVELYAEIHGLSLDYDDYVNDDYPVVLAAPTGRASKRLQESTGLEAMTIHRLIGWNQDTKPEDILENEINARLIIIDEMSMVDTWLFHQFLSAVPLDAQLIFVGDEDQLPSVGPGQVFKDLIESKAIPRVNLTEVYRQQDGSSIIELAHRMKLGQKIDITQRFHDRSFINCQANQIPTVVEKVVTSAVNKGYTMADIQVLAPMYKGNAGIKRLNQVLQDILNPKKKDTREIEFGDVVFRKGDKVLQLVNRPNDNIFNGDIGVIVGIFWAKENALNKDVLVVDFEGNEITFTKQDMMELTHAYCTSIHKSQGSEFPIVIMPIVKQYFRMLQRPILYTGLTRAKTSLVLLGDPEAFDIGLKTNGQARLTQLCTLLKNYFNSEDEEMLENTATNDTGASQTTIDDQVEAPMSSNDSGEVTSDSTKTDINVLTEATMFKIDPMINMGEITPYDFIER
>NZ_CP017115.1|WP_000734072.1|1671342_1673973_-|alanine--tRNA-ligase
MKKLKASEIRQKYLDFFVEKGHMVEPSAPLVPIDDDTLLWINSGVATLKKYFDGRETPKKPRIVNSQKAIRTNDIENVGFTARHHTFFEMLGNFSIGDYFKQEAIEFAWEFLTSDKWMGMEPDKLYVTIHPEDMEAYNIWHKDIGLEESRIIRIEGNFWDIGEGPSGPNTEIFYDRGEAYGQDDPAEEMYPGGENERYLEVWNLVFSEFNHNKDHSYTPLPNKNIDTGMGLERMASVSQNVRTNYETDLFMPIMNEIEKVSGKQYLVNNEQDVAFKVIADHIRTIAFAISDGALPANEGRGYVLRRLLRRAVRFSQTLGINEPFMYKLVDIVADIMEPYYPNVKEKADFIKRVIKSEEERFHETLEDGLAILNELIKKAKATTNEINGKDAFKLYDTYGFPIELTEEIAVQAGLKVDMTTFESEMQQQRDRARQARQNSQSMQVQSEVLKNITSASTFVGYDTATAQTTLTHLIYNGEEVSQVEAGETVYFMLTETPFYAVSGGQVADTGIVYNDNFEIAVSEVTKAPNGQNLHKGVVQFGQVNVGATVSAEVNQNDRRDIQKNHSATHLLHAALKSVLGDHVNQAGSLVEADRLRFDFSHFGPMTNDEIDQVERLVNEEIWKGIDVNIQEMDIASAKEMGAMALFGEKYGDVVRVVNMAPFSIELCGGIHVRNTSEIGLFKIVSESGTGAGVRRIEALTGKAAFLYLEDIQEKFNTMKSQLKVKSDDQVVDKLTQLQDEEKALLKQLEQRDKEITSLKMGNIENQVEEINGYKVLVTEVDVPNAKAIRSTMDDFKSKLQDTIIILASNVDDKVSMVATVPKSLTNNVKAGDLIKQMAPIVGGKGGGRPDMAQGGGTQPENISKSLSFIKDYIKNL
>NZ_CP017115.1|WP_000426912.1|1671019_1671280_-|IreB-family-regulatory-phosphoprotein
MENFDKTMKFDYEELPTQDVRDVLNNVYRTLDERGYNAVNQIVGYLLSGDPAYIPRQNEARNQIRHIDRDVIMEELVSYYLKEQNK
>NZ_CP017115.1|WP_000939059.1|1670587_1671016_-|Holliday-junction-resolvase-RuvX
MLQHKILGLDVGSRTVGIAISDIMGWTAQGLDTLRINEENNELGIDQLVDIIKKHNVGTVVIGLPKNMNNSIGFRGEASLTYKEKLLEAYPSIEIVMWDERLSTMAAERSLLEADVSRQKRKQVIDKMAAVFILQGYLDSLH
>NZ_CP017115.1|WP_000134779.1|1670264_1670573_-|DUF1292-domain-containing-protein
MTEHNHDSQLEINNEEELLTLFDEEGNEVLYRKVLEFYHPEFKKEYVILAEEGAQSDEDDMIELVPMINEPDESGDGGKLVPIETDEEWDMIEEVVNTEMEE
>NZ_CP017115.1|WP_000342266.1|1669341_1669980_-|O-methyltransferase
MDDLNKKYLIDLHQHQNSSIEVLREFAEVNEVPIVDRLTLDLIKQLIRMNNVKNILEIGTAIGYSSMQFASISDDIHVTTIERNETMIQYAKQNLATYHFENQVRIIEGNALEQFENVNDKVYDMIFIDAAKAQSKKFFEIYTPLLKHQGLVITDNVLYHGFVSDIGIVRSRNVRQMVKKVQDYNEWLIKQPGYTTNFLNIDDGLAISIKGE
>NZ_CP017115.1|WP_000137775.1|1668415_1669339_-|U32-family-peptidase
MTELLVTPKSLSHMETLIDLGADAFVIGEQKFGLRLPGEFNRQQMTEAVALAHKNDKKVYAAVNGLFHNYHLDAVEDYINFLHEIRVDRIIFGDPAVVMYVKAQENPIPLHWNAETLVTNHFQCNYWGKRGASRAVLARELNLDEIINIKENSNVEIEVQVQGMTCMFQSKRMLLGNYYTFQDRQMKIERRNDEQSLLLYDEERQNNYPVYEDYNGTHIMSPNDICLIEELAPFFEAGIDSFKIDGILQTEEYINVVTEQYRQAIDLYNEDPEIYEDEKFMLMDPIEEIQPDHRPFDEGFLYKQTVY
>NZ_CP017115.1|WP_000848304.1|1667135_1668404_-|U32-family-peptidase
MKTIEEIKSTPKTVMKKPELLAPAGNLEKLKIAVHYGADAVFLGGQEYGLRSNADNFTMEEIAEGVEFANRYGAKIYVTTNIIAHDENIEGLESYLRNLEKTGATGIIVADPLIIETCKEVAPKLEIHLSTQQSLSNYKAVEYWKEEGLDRVVLARETGAMEMREMKEKVDIEIEAFIHGAMCIAYSGRCTLSNHMTARDSNRGGCCQSCRWDYELLEVDDNGELDVFYNQGEVTPFAMSPKDLKLIESIPQMMDIGVDSLKIEGRMKSIHYIATVVSVYRKVIDAYAADPDNFKINPEWLIELDKCANRDTAPAFFEGTPGYEEQMFGQQQSKKSPFDFCGLVLDYNEDTKIATIQQRNNFKPGQEIEFFGPEIETFTQVVEAIYDEEGNSLDAARHPLQIVQIKVDRPIYPNNMMRKEIG
>NZ_CP017115.1|WP_000648617.1|1666512_1667136_-|uridine-kinase
MKATTIIGIAGGSGSGKTTVTNEIMKNLEGHSVALLAQDYYYKDQKHLTFDERLETNYDHPFAFDNDLLIENLKDLKNGKAVEVPTYDYASHTRSDITIDFKPKDVIIVEGIFALENKVLRDMMDVKIYVDTDADLRILRRLTRDTKERGRSMDSVINQYLSVVRPMHDQFIEPTKKYADIIIPEGGSNKVAIDIMTTKIQSLVSKQ
>NZ_CP017115.1|WP_000066094.1|1678043_1679162_-|tRNA-2-thiouridine(34)-synthase-MnmA
MSNKDIRVVVGMSGGVDSSVTAHVLKEQGYDVIGIFMKNWDDTDENGVCTATEDYNDVIEVCNQIGIPYYAVNFEKEYWDKVFTYFLDEYKKGRTPNPDVMCNKEIKFKAFLDHAMNLGADYVATGHYARIHRHEDGHVEMLRGVDNNKDQTYFLNQLSQQQLSKVMFPIGDIEKIEVRRIAEEQGLVTAKKKDSTGICFIGEKNFKTFLSQYLPAQPGDMITLDGKKMGKHSGLMYYTIGQRHGLGIGGDGDPWFVVGKNLKDNVLYVEQGFHHDALYSDYLIASDYSFVNPEDNDLDQGFECTAKFRYRQKDTKVFVKRENDHALRVTFAEPVRAITPGQAVVFYQGDVCLGGATIDDVFKNEGQLNYVV
>NZ_CP017115.1|WP_000409158.1|1679162_1680305_-|cysteine-desulfurase
MEIYADYAATTPVKPEVVDAMMMIYNSHYGNPSSIHAKGRDARKYLDESRRQIAQLLGADTHEIIFTSGATESNNTAIKGIVKANEQLGNHIITSKIEHHSVLHVFEQLEREGFDVTYLDVDDTGAIDLDQLEETITDKTILVSIMFVNNEVGTVQQIYDIQDIIAETNAYFHVDAVQAIGHLDVKFDEFEIDAMSITAHKFGGPKGVGALLVKDHVTLDYPQLGGEQELKRRAGTENLAQIVGMAKALQLAEKNRDDNNIHLMNLKEQFLVKLQERAIPFELNGSMTDATGHIVNLYFPFVEVETMLTLLDMAQIYVSSGSACTAGSTQPSHVLDAMFEDEERSNHSIRFSFNELTTENEINAIVAEIHKIYFKFKEES
>NZ_CP017115.1|WP_000985895.1|1680616_1681630_+|LLM-class-flavin-dependent-oxidoreductase
MAIKYSALNLVPIREGEDERTAINDMVKLAQHLDELSYERYWIAEHHNAPNLVSSATALLIQHTLEHTKHIRVGSGGIMLPNHAPLIVAEQFGTMATLFPNRVDLGLGRAPGTDMMTASALRRDQHDGVYKFPEEVSLLQQYFGPAHQQAYVRAYPAVGKNVPLYILGSSTDSAHLAARKGLPYVFAGHFAPQQMKEAIEIYKTLFEPSDVLDEPYVIVCLNTIVAENDDEAQYLASSMAQVMVSITRGRMQPVQPPTHELQNILTPREYAMAMERQKISLIGSENTVQQKIQDFMETYGEVNEIMAISYIYDKDMQLDSYRRFKNVINQINEKNTL
>NZ_CP017115.1|WP_000009238.1|1681866_1682013_-|hypothetical-protein
MSFMDKAKDAVEKFKNSDNEQVKNVKDKINEYTGSNNEEKKENEDKEK
>NZ_CP017115.1|WP_000752909.1|1682052_1682235_-|CsbD-family-protein
MADESKFDQFKGNVKETVGNVTDNKELEKEGQQDKATGKAKEVVENAKNKITDAIDKLKK
>NZ_CP017115.1|WP_000704122.1|1682334_1682757_-|Rrf2-family-transcriptional-regulator
MKISTKGRYGLTLMISLAKKEGQGCISLKSIAEENNLSDLYLEQLVGPLRNAGLIRSVRGAKGGYQLRVPAEEISAGDIIRLLEGPITFVESIESEPPAQKQLWIRMRDAVRDVLDNTTLKYLAEYVDTSEDLDGYMFYI
>NZ_CP017115.1|WP_000102740.1|1682841_1684116_+|replication-associated-recombination-protein-A
MSTEPLASRMRPKNIDEIISQQHLVGPRGIIRRMVDTKKLTSMIFYGPPGIGKTSIAKAISGSTQYKFRQLNAVTNTKKDMQLVVEEAKMSGQVILLLDEIHRLDKAKQDFLLPHLENGKIVLIGATTSNPYHAINPAIRSRAQIFELYPLNDEDVRQALTRAIEDEENGLKTYQPKIDEDAMTYFSTQSQGDVRSALNALELAVLSADNDKDGYRHVTLQDAKDCLQKGAFVSDKDGDMHYDVMSAFQKSIRGSDVNAALHYLARLIEAGDLPTIVRRLLVISYEDIGLASPNAGQRTLAAIESAERLGLPEARIPLSQAVIELCLSPKSNSAMSAIDSALSDIRNGHVGQIPNHLKDGHYQGAKDLGRSIGYKYPHQYVNGYVSQQYLPDKLKNKIYYEPKTTSKSEQQLKEIYNNLLKQRP
>NZ_CP017115.1|WP_000682646.1|1684276_1685050_-|tRNA-threonylcarbamoyladenosine-dehydratase
MKHQFSRNELAIGQQGLDLLKQQTVVILGVGGVGSFAAEALARTNIGHIILIDKDDVDITNVNRQLHALTTTVGQSKVSLMEERIKLINPDCKVTPLHMFYTEETYEEIFDNYDIDYFVDASDTIMYKVHLMKECLDRGIKVISSMGAANKTDPTRFTISDISKTHTDPMAKIIRQKLKKLGIRKGIPVVFSDESPIVIREDVKDIVGDKNAINRKGQMPPSSNAFVPSVVGLICASYVVNDVLKDIPVRRIKDKGQ
>NZ_CP017115.1|WP_001790559.1|1685049_1685178_-|hypothetical-protein
MGFIAFNKCFLVEFWENNQSDNAKYKILSYYVLMYKSVKEVK
>NZ_CP017115.1|WP_000044799.1|1685510_1687277_-|aspartate--tRNA-ligase
MSKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDREGIVQVVFNPAFSEEALKIAETVRSEYVVEVQGTVTKRDPETVNPKIKTGQVEVQVTNIKVINKSETPPFSINEENVNVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDDEGFFDIETPVLTKSTPEGARDYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQIVKCFRDEDLRADRQPEFTQVDIEMSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPRMTYKEAMRRYGSDKPDTRFEMELIDVSQLGRDMDFKVFKDTVENDGEIKAIVAKGAAEQYTRKDMDALTEFVNIYGAKGLAWVKVVEDGLTGPIGRFFETENVETLLTLTGAEAGDLVMFVADKPNVVAQSLGALRVKLAKELGLIDETKLNFLWVTDWPLLEYDEDAKRYVAAHHPFTSPKEADIAKLGTAPEEAEANAYDIVLNGYELGGGSIRIHDGELQEKMFEVLGFTKEQAQEQFGFLLDAFKYGAPPHGGIALGLDRLVMLLTNRTNLRDTIAFPKTASATCLLTNAPGEVSDKQLEELSLRIRH

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Crispr_ID: NZ_CP017115_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017115_7

1763643-1763729

Orphan

Consensus_repeat	Method
ATGCAAGTTGGGGTGGGGCCCCAACATAGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP017115_7

>merge|NZ_CP017115|7|1763643-1763729|CRISPRCasFinder
ATGCAAGTTGGGGTGGGGCCCCAACATAGAGAATTTCGAAAAGAAATTCTACAGACCATGCAAGTTGGGGTGGGCCCCAACATAGAA

>NZ_CP017115|7|7|1763643-1763729|CRISPRCasFinder
ATGCAAGTTGGGGTGGGGCCCCAACATAGA	GAATTTCGAAAAGAAATTCTACAGACC
ATGCAAGTTGGGGTGGGCCCCAACATAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017115.1\|WP_000136253.1\|1772640_1773135_-\|thiol-peroxidase	unknown	unknown	gnl\|CDD\|179055
NZ_CP017115.1\|WP_000777188.1\|1766040_1766730_-\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|234811
NZ_CP017115.1\|WP_000717561.1\|1754294_1755263_-\|ATP-dependent-6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111
NZ_CP017115.1\|WP_000123164.1\|1748020_1749289_-\|NADP-dependent-isocitrate-dehydrogenase	unknown	unknown	gnl\|CDD\|180792
NZ_CP017115.1\|WP_000058389.1\|1757527_1758757_-\|NAD-dependent-malic-enzyme-4	unknown	unknown	gnl\|CDD\|235976
NZ_CP017115.1\|WP_000634175.1\|1769534_1770035_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP017115.1\|WP_000689998.1\|1768275_1769394_-\|alanine-dehydrogenase	unknown	unknown	gnl\|CDD\|240630
NZ_CP017115.1\|WP_000277602.1\|1765322_1765736_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP017115.1\|WP_000471572.1\|1756475_1757333_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	unknown	unknown	gnl\|CDD\|235547
NZ_CP017115.1\|WP_000160435.1\|1763819_1765118_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|226594
NZ_CP017115.1\|WP_000883645.1\|1755531_1756476_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	unknown	unknown	gnl\|CDD\|235580
NZ_CP017115.1\|WP_001232648.1\|1752515_1754273_-\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235784
NZ_CP017115.1\|WP_000161666.1\|1766904_1767960_+\|aminopeptidase-P-family-protein	unknown	unknown	gnl\|CDD\|223085
NZ_CP017115.1\|WP_000829167.1\|1749337_1750459_-\|citrate-synthase	unknown	unknown	gnl\|CDD\|184468
NZ_CP017115.1\|WP_000818525.1\|1750806_1752168_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NZ_CP017115.1\|WP_000040069.1\|1770280_1771483_-\|acetate-kinase	unknown	unknown	gnl\|CDD\|234680
NZ_CP017115.1\|WP_000226910.1\|1759206_1762404_-\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|223660
NZ_CP017115.1\|WP_000626074.1\|1762424_1763366_-\|pApA-hydrolase-Pde2	unknown	unknown	gnl\|CDD\|223691
NZ_CP017115.1\|WP_001789984.1\|1768053_1768152_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_000840574.1\|1771570_1772518_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|223897

Protein	Function_ID	Function_description	E-value
NZ_CP017115.1\|WP_000136253.1\|1772640_1773135_-\|thiol-peroxidase	gnl\|CDD\|179055	PRK00522, tpx, thiol peroxidase.	8.69777e-99
NZ_CP017115.1\|WP_000777188.1\|1766040_1766730_-\|metal-dependent-hydrolase	gnl\|CDD\|234811	PRK00685, PRK00685, metal-dependent hydrolase; Provisional.	3.09103e-133
NZ_CP017115.1\|WP_000717561.1\|1754294_1755263_-\|ATP-dependent-6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	0
NZ_CP017115.1\|WP_000123164.1\|1748020_1749289_-\|NADP-dependent-isocitrate-dehydrogenase	gnl\|CDD\|180792	PRK07006, PRK07006, isocitrate dehydrogenase; Reviewed.	0
NZ_CP017115.1\|WP_000058389.1\|1757527_1758757_-\|NAD-dependent-malic-enzyme-4	gnl\|CDD\|235976	PRK07232, PRK07232, bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed.	0
NZ_CP017115.1\|WP_000634175.1\|1769534_1770035_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	9.27306e-36
NZ_CP017115.1\|WP_000689998.1\|1768275_1769394_-\|alanine-dehydrogenase	gnl\|CDD\|240630	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains. Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.	0
NZ_CP017115.1\|WP_000277602.1\|1765322_1765736_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	6.00154e-19
NZ_CP017115.1\|WP_000471572.1\|1756475_1757333_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	gnl\|CDD\|235547	PRK05654, PRK05654, acetyl-CoA carboxylase carboxyltransferase subunit beta.	0
NZ_CP017115.1\|WP_000160435.1\|1763819_1765118_-\|CBS-domain-containing-protein	gnl\|CDD\|226594	COG4109, COG4109, Predicted transcriptional regulator containing CBS domains [Transcription].	0
NZ_CP017115.1\|WP_000883645.1\|1755531_1756476_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	gnl\|CDD\|235580	PRK05724, PRK05724, acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated.	0
NZ_CP017115.1\|WP_001232648.1\|1752515_1754273_-\|pyruvate-kinase	gnl\|CDD\|235784	PRK06354, PRK06354, pyruvate kinase; Provisional.	0
NZ_CP017115.1\|WP_000161666.1\|1766904_1767960_+\|aminopeptidase-P-family-protein	gnl\|CDD\|223085	COG0006, PepP, Xaa-Pro aminopeptidase [Amino acid transport and metabolism].	2.15375e-126
NZ_CP017115.1\|WP_000829167.1\|1749337_1750459_-\|citrate-synthase	gnl\|CDD\|184468	PRK14035, PRK14035, citrate synthase; Provisional.	0
NZ_CP017115.1\|WP_000818525.1\|1750806_1752168_+\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	0
NZ_CP017115.1\|WP_000226910.1\|1759206_1762404_-\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|223660	COG0587, DnaE, DNA polymerase III, alpha subunit [DNA replication, recombination, and repair].	0
NZ_CP017115.1\|WP_000626074.1\|1762424_1763366_-\|pApA-hydrolase-Pde2	gnl\|CDD\|223691	COG0618, COG0618, Exopolyphosphatase-related proteins [General function prediction only].	1.30182e-98
NZ_CP017115.1\|WP_000040069.1\|1770280_1771483_-\|acetate-kinase	gnl\|CDD\|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	0
NZ_CP017115.1\|WP_000840574.1\|1771570_1772518_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|223897	COG0827, COG0827, Adenine-specific DNA methylase [DNA replication, recombination, and repair].	2.86206e-56

>NZ_CP017115.1|WP_000626074.1|1762424_1763366_-|pApA-hydrolase-Pde2
MISTLNEIMKCIEDNDTIIIHRHVRPDPDAYGSQLGLKYYIQQKFPQKQVFAVGEAESSLSFIGELDNIDDKTYQDALVIVCDTANAPRIDDERYSTGRKLIKIDHHPAVDQYGDINLVNTNASSTSEIIYDLISHFNDEAIVNKDIASVLYLGIVGDTGRFLFNNTSEHTMEIAGKLIGHDIDHNALLNKMMEKDPKMLPFQGYVLQHFELMDDGFCQVKITEDVLEQFGIQPNEASQFVNTIADIKGLKIWVFAVDEGNEIRCRLRSKGQLIINDIAQDFGGGGHPNASGVSVDSWDEFEQLATALRTKLN
>NZ_CP017115.1|WP_000226910.1|1759206_1762404_-|DNA-polymerase-III-subunit-alpha
MVAYLNIHTAYDLLNSSLKIEDAVRLAVSENVDALAITDTNVLYGFPKFYDACIANNIKPIFGMTIYVTNGLNTVETVVLAKNNDGLKDLYQLSSEIKMNALEHVSFELLKRFSNNMIIIFKKVGDQHRDIVQVFETHNDTYMDHLSISIQGRKHVWIQNVCYQTRQDADTISALAAIRDNTKLDLIHDQEDFGAHFLTEKEINQLDINQEYLTQVDVIAQKCDAELKYHQSLLPQYETPNDESAKKYLWRVLVTQLKKLELNYDVYLERLKYEYKVITNMGFEDYFLIVSDLIHYAKTNDVMVGPGRGSSAGSLVSYLLGITTIDPIKFNLLFERFLNPERVTMPDIDIDFEDTRRERVIQYVQEKYGELHVSGIVTFGHLLARAVARDVGRIMGFDEVTLNEISSLIPHKLGITLDEAYQIDDFKKFVHRNHRHERWFSICKKLEGLPRHTSTHAAGIIINDHPLYEYAPLTKGDTGLLTQWTMTEAERIGLLKIDFLGLRNLSIIHQILTQVKKDLGINIDIEKIPFDDQKVFELLSQGDTTGIFQLESDGVRSVLKKLKPEHFEDIVAVTSLYRPGPMEEIPTYITRRHDPSKVQYLHPHLEPILKNTYGVIIYQEQIMQIASTFANFSYGEADILRRAMSKKNRAVLESERQHFIEGAKQNGYHEDISKQIFDLILKFADYGFPRAHAVSYSKIAYIMSFLKVHYPNYFYANILSNVIGSEKKTAQMIEEAKKQGITILPPNINESHWFYKPSQEGIYLSIGTIKGVGYQSVKVIVDERYQNGKFKDFFDFARRIPKRVKTRKLLEALILVGAFDAFGKTRSTLLQAIDQVLDGDLNIEQDGFLFDILTPKQMYEDKEELPDALISQYEKEYLGFYVSQHPVDKKFVAKQYLTIFKLSNAQNNKPILVQFDKVKQIRTKNGQNMAFVTLNDGIETLDGVIFPNQFKKYEELLSHNDLFIVSGKFDHRKQQRQLIINEIQTLATFEEQKLAFAKQIIIRNKSQIDMFEEMIKATKENANDVVLSFYDETIKQMTTLGYINQKDSMFNNFIQSFNPSDIRLI
>NZ_CP017115.1|WP_000058389.1|1757527_1758757_-|NAD-dependent-malic-enzyme-4
MSLRDEALEMHKRNQGKLEVKPNVKVTNKEELSLAYSPGVAEPCKDIYEDKRKVYDYTIKGNTVAVITDGTAVLGLGNIGPEASIPVMEGKAVLFKSFAGINGVPIALNTTDTEEIIKTVKLLEPNYGGINLEDISAPRCFEIEERLKKETNIPVFHDDQHGTAIVTMAGLVNALRVVNKDIAKIKVVLNGAGAAGIAIVKLLYAYGVRNMVMCDSRGAIFEGRSYGMNPTKDVVAKWTNKDKIEGSLEEVVKDADVFIGVSVANALSQDMVKSMADNPIIFAMANPNPEIIPDDAKAAGARVVGTGRSDYPNQINNVLAFPGIFRGALEVEATHINEEMKKAAVEAIADLIDSSELNEDYCIPGPFDKRVAPSVARNVAKAAMESGVARIEVDPQDVYDKTMKLTDLQ
>NZ_CP017115.1|WP_000471572.1|1756475_1757333_-|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta
MFKDFFNRTKKKKYLTVQDSKNNDVPAGIMTKCPKCKKIMYTKELAENLNVCFNCDHHIALTAYKRIEAISDEGSFTEFDKGMTSANPLDFPSYLEKIEKDQQKTGLKEAVVTGTAQLDGMKFGVAVMDSRFRMGSMGSVIGEKICRIIDYCTENRLPFILFSASGGARMQEGIISLMQMGKTSVSLKRHSDAGLLYISYLTHPTTGGVSASFASVGDINLSEPKALIGFAGRRVIEQTINEKLPDDFQTAEFLLEHGQLDKVVHRNNMRQTLSEILKIHQEVTK
>NZ_CP017115.1|WP_000883645.1|1755531_1756476_-|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha
MLDFEKPLFEIRNKIESLKESQDKNDVDLQEEIDMLEASLERETKKIYTNLKPWDRVQIARLQERPTTLDYIPYIFDSFMELHGDRNFRDDPAMIGGIGFLNGRAVTVIGQQRGKDTKDNIYRNFGMAHPEGYRKALRLMKQAEKFNRPIFTFIDTKGAYPGKAAEERGQSESIATNLIEMASLKVPVIAIVIGEGGSGGALGIGIANKVLMLENSTYSVISPEGAAALLWKDSNLAKIAAETMKITAHDIKQLGIIDDVISEPLGGAHKDIEQQALAIKSAFVAQLDSLESLSRDEIANDRFEKFRNIGSYIE
>NZ_CP017115.1|WP_000717561.1|1754294_1755263_-|ATP-dependent-6-phosphofructokinase
MKKIAVLTSGGDSPGMNAAVRAVVRTAIYNEIEVYGVYHGYQGLLNDDIHKLELGSVGDTIQRGGTFLYSARCPEFKEQEVRKVAIENLRKRGIEGLVVIGGDGSYRGAQRISEECKEIQTIGIPGTIDNDINGTDFTIGFDTALNTIIGLVDKIRDTASSHARTFIIEAMGRDCGDLALWAGLSVGAETIVVPEVKTDIKEIADKIEQGIKRGKKHSIVLVAEGCMTAQDCQKELSQYINVDNRVSVLGHVQRGGSPTGADRVLASRLGGYAVDLLMQGETAKGVGIKNNKIVATSFDEIFDGKDHKFDYSLYELANKLSI
>NZ_CP017115.1|WP_001232648.1|1752515_1754273_-|pyruvate-kinase
MRKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAILLDTKGPEIRTHNMKDGIIELERGNEVIVSMNEVEGTPEKFSVTYENLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNLPGVRVSLPGITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFPKIENQEGIDNIAEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSLVNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVTPSEETARQCSIVWGVQPVVKKGRKSTDALLNNAVATAVETGRVSNGDLIIITAGVPTGETGTTNMMKIHLVGDEIANGQGIGRGSVVGTTLVAETVKDLEGKDLSDKVIVTNSIDETFVPYVEKALGLITEENGITSPSAIVGLEKGIPTVVGVEKAVKNISNNMLVTIDAAQGKIFEGYANVL
>NZ_CP017115.1|WP_000818525.1|1750806_1752168_+|amino-acid-permease
MAEKLQRELSNRHIQLIAIGGAIGTGLFLGAGQTIALTGPSILLTYIIIGFMLFMFMRGLGEIIIQNTEFKSFADVTNTYIGPFAGFVTGWTYWFCWIITGMAEVTAVAKYVSFWFPEIPNWISALFCVLLLMSFNLLSARLFGELEFWFSIIKIATIIGLIVVGFVMILFAFKTQFGHASFTNLYEHGIFAKGASGFFMSFQMALFSFVGIEMIGVTAGETKDPVKTIPKAINSVPIRILIFYVGALAVIMSIIPWQQVDPDNSPFVKLFALIGIPFAAGLINFVVLTAAASSCNSGIFSNSRMLFGLSSQQQAPPNFSKTNKYGVPHVAIFASSALLLVAALLNYIFPDATKVFTYVTTISTVLFLVVWGLIIIAYINYSRKNPDLHKNATYKLLGGKYMGYLIFVFFIFVFGLLFINVDTRRAIYFIPIWFILLAFMYLRYKRIAAKSNK
>NZ_CP017115.1|WP_000829167.1|1749337_1750459_-|citrate-synthase
MAELQRGLEGVIAAETKISSIIESQLTYAGYDIDDLAENAQFEEVIFLLWNYRLPNEEELAHLKGKLNQYMTLNPRVYTHFEEYVTDHVHPMTALRTSLSYIAHFDPDAENESDENRYERAMRIQAKVASLVTAFARVRQDKEPLKPNPDLSYAANFLYMLRGELPTDIEVEAFNKALILHADHELNASAFTARCAVSSLSDMYSGIVAAVGSLKGPLHGGANEQVMTMLSEIGSIENVDAYLDEKFANKDKVMGFGHRVYKDGDPRAKYLREMSRQITKDAGREELFEMSVKMEKRMAEEKGLIPNVDFYSASVYHCMEIPHDLFTPIFAVSRSAGWIAHILEQYKDNRIMRPRAKYIGETNRKYIPLEERK
>NZ_CP017115.1|WP_000123164.1|1748020_1749289_-|NADP-dependent-isocitrate-dehydrogenase
MTAEKITQGTEGLNVPNEPIIPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEWLPQETLDTIKEYLIAVKGPLTTPIGGGIRSLNVALRQELDLFTCLRPVRWFKGVPSPVKRPQDVDMVIFRENTEDIYAGIEFKEGTTEVKKVIDFLQNEMGATNIRFPETSGIGIKPVSKEGTERLVRAAIQYAIDNNRKSVTLVHKGNIMKFTEGSFKQWGYDLALSEFGDQVFTWQQYDEIVEKEGRDAANAAQEKAEKEGKIIIKDSIADIFLQQILTRPAEHDVVATMNLNGDYISDALAAQVGGIGIAPGANINYETGHAIFEATHGTAPKYAGLNKVNPSSVILSSVLMLEHLGWQEAADKITDSIEDTIASKVVTYDFARLMDGAEEVSTSAFADELIKNLK
>NZ_CP017115.1|WP_000160435.1|1763819_1765118_-|CBS-domain-containing-protein
MTKHEQILDYIESLSIGSKISVRKIAKFLNVSEGTAYRAIKDADKMGMVATIDRVGTVRIEKRNRNEIEHLTFNEIVNIIDGQVLGGNKGITKMVSKFAIGAMELKDILKYIGPKTLLIVGNREDVQIEALKRGTAILITGGFKPSNKVINFANEHDLPVLSSSYDTFLVANIINKALFNQKIRKDILIVQDIMTPLDDLSVLFDTMKIADYKRMANRTGHTRFPVVNESYKLVGIVTSREMINTKDDDEIDKVMTRNPIYVNAMSTVASCAHMMIWEGIELIPVVSSNKKTVGVINRQDVLKSMQLLGRQPQMGETINDQIAKYITMNQDGITVEVSPLLINHYGTVSKAAFVSIIEETIQYEMRKFKKGNVMIENLNIVYIKTVPIESHITVRFGILDVGRNFAKIEVNMHSQNDKVASALVICQMFDEV
>NZ_CP017115.1|WP_000277602.1|1765322_1765736_+|universal-stress-protein
MYKNILLGVDTQLKNEKALKEVSKLAGEGTVVTVLNAISEQDAQASIKAGVHLNKLTEERSKRLEKTRKALEDYGIDYDQIIVRGNAKEELLKHANSGKYEIVVLSNRKAEDKKKFVLGSVSHKVAKRATIPVLIVK
>NZ_CP017115.1|WP_000777188.1|1766040_1766730_-|metal-dependent-hydrolase
MKLSFHGQSTIYLEGNNKKVIVDPFISNNPKCDLNIETVQVDYIVLTHGHFDHFGDVVELAKKTGATVIGSAEMADYLSSYHGVENVHGMNIGGKANFDFGSVKFVQAFHSSSFTHENGIPVYLGMPMGIVFEVEGKTIYHTGDTGLFSDMSLIAKRHPVDVCFVPIGDNFTMGIDDASYAINEFIKPKISVPIHYDTFPLIEQDPQQFKDAVNVGDVQILKPGESVQF
>NZ_CP017115.1|WP_000161666.1|1766904_1767960_+|aminopeptidase-P-family-protein
MTKISKIIDELNNQQADAAWITTPLNVYYFTGYRSEPHERLFALLIKKDGKQVLFCPKMEVEEVKASPFTGEIVGYLDTENPFSLYPQTINKLLIESEHLTVARQKQLISGFNVNSFGDVDLTIKQLRNIKSEDEISKIRKAAELADKCIEIGVSYLKEGVTEREVVNHIEQTIKQYGVNEMSFDTMVLFGDHAASPHGTPGDRRLKSNEYVLFDLGVIYEHYCSDMTRTIKFGEPSKEAQEIYNIVLEAETSAIQAIKPGIPLKDIDHIARNIISEKGYGEYFPHRLGHGLGLQEHEYQDVSSTNSNLLEAGMVITIEPGIYVPGVAGVRIEDDILVTNEGYEVLTHYEK
>NZ_CP017115.1|WP_001789984.1|1768053_1768152_-|hypothetical-protein
MNDIDLIHYMLLMNIPAYVFLACLLHIAFRLG
>NZ_CP017115.1|WP_000689998.1|1768275_1769394_-|alanine-dehydrogenase
MKIGIPREIKNNENRVGLSPSGVHALVESGHTVLVETNAGSGSFFEDVDYKEAGAEIVAEQAKVWDVDMVIKVKEPLESEYPYFKEGLVLFTYLHLANEEKLTQALIDRKVISIAYETVQLPDRSLPLLSPMSEVAGRMSAQVGAEFLQKLNGGMGILLGGVPGVPKGKVTIIGGGQAGTNAAKIALGLGADVTILDVNPKRLQQLDDLFGGRVHTIMSNPLNIELYVKQSDLVIGAVLIPGAKAPRLVTEDMIKQMKNGSVIIDIAIDQGGIFETTDKITTHDDPTYIKHGVVHYAVANMPGAVPRTSTLALNNATLPYALMLANKGYREAFKSNQPLSLGLNTYKGHVTNKGVAEAFEMEYKSVEEALQL
>NZ_CP017115.1|WP_000634175.1|1769534_1770035_+|universal-stress-protein
MITYKNILIAVDGSHEAEWAFNRAVGVAKRNDAKLTIVNVIDSRTYSSYEVYDAQFTEKSKHFAEELLNGYKEVATNAGVKDVETRLEFGSPKSIIPKKLAHEINADLIMSGTSGLNAVERFIVGSVSESIVRHAPCDVLVVRTEELPADFQPQVATTQLREKYQN
>NZ_CP017115.1|WP_000040069.1|1770280_1771483_-|acetate-kinase
MSKLILAINAGSSSLKFQLIRMPEEELVTKGLVERIGLKDSIFTIEVNGEKVKTVQDIKDHVEAVDIMLDAFKAHNIINDINDIDGTGHRVVHGGEKFPESVAITDEVEKEIEELSELAPLHNPANLMGIRAFRKLLPNIPHVAIFDTAFHQTMPEKAYLYSLPYHYYKDYGIRKYGFHGTSHKFVSQRAAEMLDKPIEDLRIISCHIGNGASIAAIDGGKSIDTSMGFTPLAGVTMGTRSGNIDPALIPFIMEKTGKTAEQVLEILNKESGLLGLSGTSSDLRDLSEEAESGKARSQMALDVFASKIHKYIGSYAARMHGVDVIVFTAGIGENSVEIRAKVLEGLEFMGVYWDPKKNENLLRGKEGFINYPHSPVKVVVIPTDEESMIARDVMTFGGLK
>NZ_CP017115.1|WP_000840574.1|1771570_1772518_-|class-I-SAM-dependent-methyltransferase
MAEQQTIMERLFHTLDEKAKTLNNENGQSFIENLGLAMEQVYTNERGLLEQSTLQDRRKAFQFAYLSLMQEEKIQANHQITPDSIGLILGFLVERFMNNQEELHIVDIASGAGHLSATVKEVLPEIAVMHHLIEVDPVLSRVSVHLANFLEIPFDVYPQDAIMPLPLEEADIVIGDFPVGYYPIDERSKEFKLGFEEGHSYSHYLLIEQAINALKDAGYAFLVVPSNIFTGEHVKQLEKYIATETEMQAFLNLPPTLFKNEKARKSILILQKKKSGETKPVEVLLANIPDFKIPSQFQGFMTELNQWMDTNRPKK
>NZ_CP017115.1|WP_000136253.1|1772640_1773135_-|thiol-peroxidase
MTEITFKGGPIHLKGQQINEGDFAPDFTVLDNDLNQVTLADYAGKKKLISVVPSIDTGVCDQQTRKFNSDASKEEGIVLTISADLPFAQKRWCASAGLDNVITLSDHRDLSFGENYGVVMEELRLLARAVFVLDADNKVVYKEIVSEGTDFPDFDAALAAYKNI

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Crispr_ID: NZ_CP017115_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017115_8

1939229-1939356

Orphan

Consensus_repeat	Method
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP017115_8

>merge|NZ_CP017115|8|1939229-1939356|CRISPRCasFinder
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTCATTCCAGGAAGGAATGTATTCTAAGAGTTGAAATACTCCCGCATTATTATTAAATTATGGAGCGGAAGATAGGATTTGCACCTATACCTC

>NZ_CP017115|8|8|1939229-1939356|CRISPRCasFinder
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTC	ATTCCAGGAAGGAATGTATTCTAAGAGTTGAAATACTCCCGCATTATTATTA
AATTATGGAGCGGAAGATAGGATTTGCACCTATACCTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017115.1\|WP_000649907.1\|1935787_1937245_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223836
NZ_CP017115.1\|WP_000597238.1\|1952327_1954064_-\|SAV1866-family-putative-multidrug-efflux-ABC-transporter	unknown	unknown	gnl\|CDD\|224055
NZ_CP017115.1\|WP_001802394.1\|1933794_1934937_-\|tRNA-epoxyqueuosine(34)-reductase-QueG	unknown	unknown	gnl\|CDD\|272993
NZ_CP017115.1\|WP_000869444.1\|1947967_1948918_-\|2-hydroxyacid-dehydrogenase	unknown	unknown	gnl\|CDD\|240632
NZ_CP017115.1\|WP_001011599.1\|1949459_1950749_+\|glutamate-1-semialdehyde-2,1-aminomutase	unknown	unknown	gnl\|CDD\|183493
NZ_CP017115.1\|WP_000251255.1\|1954354_1954897_-\|DUF402-domain-containing-protein	unknown	unknown	gnl\|CDD\|184219
NZ_CP017115.1\|WP_000886468.1\|1957625_1958462_-\|membrane-protein	unknown	unknown	gnl\|CDD\|224596
NZ_CP017115.1\|WP_000116229.1\|1929802_1931188_-\|class-II-fumarate-hydratase	unknown	unknown	gnl\|CDD\|234779
NZ_CP017115.1\|WP_001144055.1\|1935072_1935801_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP017115.1\|WP_001236371.1\|1951041_1952136_+\|aromatic-acid-exporter-family-protein	unknown	unknown	gnl\|CDD\|226614
NZ_CP017115.1\|WP_000031108.1\|1932384_1932537_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_000379098.1\|1956387_1957365_+\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|224899
NZ_CP017115.1\|WP_000939521.1\|1948923_1949379_-\|thioredoxin-dependent-thiol-peroxidase	unknown	unknown	gnl\|CDD\|224146
NZ_CP017115.1\|WP_000063582.1\|1937502_1938564_-\|PTS-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226167
NZ_CP017115.1\|WP_001251224.1\|1932561_1933161_-\|glucosamine-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|223440
NZ_CP017115.1\|WP_000110011.1\|1947424_1947871_-\|peroxide-responsive-transcriptional-repressor-PerR	unknown	unknown	gnl\|CDD\|223806
NZ_CP017115.1\|WP_000284760.1\|1955198_1956236_-\|A/G-specific-adenine-glycosylase	unknown	unknown	gnl\|CDD\|224115
NZ_CP017115.1\|WP_000901023.1\|1931383_1931779_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_000669376.1\|1928520_1929342_+\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NZ_CP017115.1\|WP_000181394.1\|1933319_1933790_-\|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	unknown	unknown	gnl\|CDD\|223297

Protein	Function_ID	Function_description	E-value
NZ_CP017115.1\|WP_000649907.1\|1935787_1937245_-\|ABC-transporter-permease-subunit	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	2.14709e-98
NZ_CP017115.1\|WP_001802394.1\|1933794_1934937_-\|tRNA-epoxyqueuosine(34)-reductase-QueG	gnl\|CDD\|272993	TIGR00276, iron-sulfur_cluster-binding_protein, epoxyqueuosine reductase. This model was rebuilt to exclude archaeal homologs, now that there is new information that bacterial members are epoxyqueuosine reductase, QueG, involved in queuosine biosynthesis for tRNA maturation. [Protein synthesis, tRNA and rRNA base modification].	3.47689e-179
NZ_CP017115.1\|WP_000869444.1\|1947967_1948918_-\|2-hydroxyacid-dehydrogenase	gnl\|CDD\|240632	cd12155, PGDH_1, Phosphoglycerate Dehydrogenase, 2-hydroxyacid dehydrogenase family. Phosphoglycerate Dehydrogenase (PGDH) catalyzes the NAD-dependent conversion of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first step in serine biosynthesis. Over-expression of PGDH has been implicated as supporting proliferation of certain breast cancers, while PGDH deficiency is linked to defects in mammalian central nervous system development. PGDH is a member of the 2-hydroxyacid dehydrogenase family, enzymes that catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-Adenosylhomocysteine Hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann-fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	3.07559e-136
NZ_CP017115.1\|WP_001011599.1\|1949459_1950749_+\|glutamate-1-semialdehyde-2,1-aminomutase	gnl\|CDD\|183493	PRK12389, PRK12389, glutamate-1-semialdehyde aminotransferase; Provisional.	0
NZ_CP017115.1\|WP_000251255.1\|1954354_1954897_-\|DUF402-domain-containing-protein	gnl\|CDD\|184219	PRK13662, PRK13662, hypothetical protein; Provisional.	1.4746e-126
NZ_CP017115.1\|WP_000116229.1\|1929802_1931188_-\|class-II-fumarate-hydratase	gnl\|CDD\|234779	PRK00485, fumC, fumarate hydratase; Reviewed.	0
NZ_CP017115.1\|WP_001144055.1\|1935072_1935801_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	2.22702e-152
NZ_CP017115.1\|WP_001236371.1\|1951041_1952136_+\|aromatic-acid-exporter-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	1.5476e-86
NZ_CP017115.1\|WP_000886468.1\|1957625_1958462_-\|membrane-protein	gnl\|CDD\|224596	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	0.000164936
NZ_CP017115.1\|WP_000379098.1\|1956387_1957365_+\|metal-dependent-hydrolase	gnl\|CDD\|224899	COG1988, COG1988, Predicted membrane-bound metal-dependent hydrolases [General function prediction only].	2.87563e-40
NZ_CP017115.1\|WP_000939521.1\|1948923_1949379_-\|thioredoxin-dependent-thiol-peroxidase	gnl\|CDD\|224146	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	1.44283e-68
NZ_CP017115.1\|WP_000063582.1\|1937502_1938564_-\|PTS-transporter-subunit-IIC	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	2.31644e-122
NZ_CP017115.1\|WP_001251224.1\|1932561_1933161_-\|glucosamine-6-phosphate-isomerase	gnl\|CDD\|223440	COG0363, NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism].	1.49007e-10
NZ_CP017115.1\|WP_000110011.1\|1947424_1947871_-\|peroxide-responsive-transcriptional-repressor-PerR	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	6.09298e-56
NZ_CP017115.1\|WP_000284760.1\|1955198_1956236_-\|A/G-specific-adenine-glycosylase	gnl\|CDD\|224115	COG1194, MutY, A/G-specific DNA glycosylase [DNA replication, recombination, and repair].	5.5924e-157
NZ_CP017115.1\|WP_000597238.1\|1952327_1954064_-\|SAV1866-family-putative-multidrug-efflux-ABC-transporter	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NZ_CP017115.1\|WP_000669376.1\|1928520_1929342_+\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	3.35529e-78
NZ_CP017115.1\|WP_000181394.1\|1933319_1933790_-\|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	gnl\|CDD\|223297	COG0219, CspR, Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis].	1.70324e-88

>NZ_CP017115.1|WP_000063582.1|1937502_1938564_-|PTS-transporter-subunit-IIC
MSNANNADNKQFFSKILNSIGAGVVIALVPNALLGEVLKIFKSGNEILELTYQLVILIQSFMAFIIGVLAAHQFKFNGAGAAIVGTSAMIGSGAVVYSNNSFMLKGIGDIINTSLVVIIACLIYMVLQNKLGSFELIILPVLVPIVSGGIGLITLPYIRKITQAIGNVIHSFTDLNPLLMSILISVAFSLLMVTPISLVAIATAISLNGLGSGAANLGIVAACVTFLFGSLRVNSIGVNAVLLIGAAKMMIPVYLKNLIISIPLTINGIITGIIAYVLQVKGTPLSAGFGYTGLVGPINAFNRMSGDPTMNIILLALGYFVIPFVSAFIVHELCKKFIPIYSNDIYKFEVPKQ
>NZ_CP017115.1|WP_000649907.1|1935787_1937245_-|ABC-transporter-permease-subunit
MKCLIRFILVLGLLISSAMVYINPTAHAEQDQTWEKIKERGELRVGLSADYAPMEFEHTVNGKTEYAGVDIDLAKKIAKDNNLKLKIVNMSFDSLLGALKTGKIDIIISGMTSTPERKKQVDFSDSYMMTKNIMLVKKDKVNEYKDIKDFNNKKVGAQKGTEQEKIAQTEIENASITSLSRLPDVILALKSGKVEGAVVEKPVAEAYLKQNPKLGISNVKFNEEEKDTVIAVPKDSPKLLSQINKTIKEVKDKGLIDKYMTNAANAMNDDSGFISKYGSFFLKGIKITILISLIGVALGSILGAFVALMKLSKIKIISWIASIYIEILRGTPMLVQVFIVFFGITAALGLDISALVCGTIALVINSSAYIAEIIRAGINAVDKGQMEAARSLGLNYRQTMKSVIMPQAIKNILPALGNEFVTLIKESSIVSTIGVGEIMFNAQVVQGISFDPFTPLIVAAALYFVLTFVLTRIMNMIEGRLNASD
>NZ_CP017115.1|WP_001144055.1|1935072_1935801_-|amino-acid-ABC-transporter-ATP-binding-protein
MPVIKINNLNKVFGDNEVLKDINLEINQGEVVAIIGPSGSGKSTLLRCMNLLEVPTKGQVIFEGNDLTEKGTQVDKLRQKMGMVFQNFNLFPHKKVVDNIILAPKLLKKDNNDELHKEALSLLDKVGLKEKADVYPNQLSGGQKQRVAIARALAMHPDVILFDEPTSALDPEVVGDVLKVMKDLAKEGMTMVVVTHEMGFAKDVSDKVIFMADGVVVESGTPVEIFEQPQHERTQNFLARVL
>NZ_CP017115.1|WP_001802394.1|1933794_1934937_-|tRNA-epoxyqueuosine(34)-reductase-QueG
MGGIRLDTKQLKQDIIDYAYTIGIDSIGFTTADPFDELKQKLEAYHANGYASGFEESDIALRTEPKLSLPTARSIIAIAVGYPNKLKGAPKSVRGDRRGLFARASWGQDYHTIMRKRLDMLASFIESKVPDVEIKSMVDTGVLSDRAVAERAGLGFVGRNGFVINPKLGTWTYLGEMLVSIPFEPDDPLLDSCGDCTICVDRCPTSALVGNGQLNSQKCISFLTQTKGYMPDQYRYKIGNRLYGCDTCQQVCPKNRGINTEQDDIILEPEILKPRLVPLLRMSNKEFKQTYGHLAGAWRGKKPIQRNAILGLAHFNEVDAIPELKKVATTDERPMIRATAYWAIGQILGEEARDFINANYDQEDAEVQNEMIKGLDTRRE
>NZ_CP017115.1|WP_000181394.1|1933319_1933790_-|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL
MTNHIVLYQPEIPANTGNIARTCAGTNTHLHLIKPLGFRTDDKMLKRAGLDYWEFVNITYHDSIEAFFEATNGEYYLLTKFGKKTYSDFDFSNHDKDFYFIFGKETTGLPDWVKEKYQDTALRIPMSEHIRSLNLSNTAALLIYEALRQQDFPGLN
>NZ_CP017115.1|WP_001251224.1|1932561_1933161_-|glucosamine-6-phosphate-isomerase
MAMNFKVFDNSQLVAEYAADIIRKQFNNNPTTIAGFHLDTDQAPVLDELKKNVEKHAVDFSQINILDYDDKKSYFEALGVPAGQVYPIAYEKDAIELIADKIKTKENKGKLTLQVVSIDEQGKLNVSIRQGLMEAREIFLVVTGANKRDVVEKLYQENGKTSFEPADLKAHRMVNVILDKEAAAGLPEDVKAYFTSRFA
>NZ_CP017115.1|WP_000031108.1|1932384_1932537_-|hypothetical-protein
MSKDKDPKLNYHEEENSMVTDFEDLKELGKEMEQISDQNDQEKNSEEDSQ
>NZ_CP017115.1|WP_000901023.1|1931383_1931779_-|hypothetical-protein
MLGKYWIQLLIATVIISLISIKAFPLAIGALYLPVIFKVIKLQLNLSKGLIDDVNAQTFIKSNQSGIVISVICCLLITGILYYTLDGFYASLTGVLGTLVALNPYTTIVSAVLYILTAIATVEATKTKYRN
>NZ_CP017115.1|WP_000116229.1|1929802_1931188_-|class-II-fumarate-hydratase
MSVRIEHDTFGEIEVPADKYWGAQTERSKRNFPVGKERMPIEVVYGFAQLKRAAALANFDLGKLSEAKKDAIVYACDQILSGELDEHFPLVVWQTGSGTQSNMNVNEVVSYVANMYLKDHQIDESIHPNDDVNKSQSSNDTFPTAMHVALYQEVETKLEPALKLLRNTLKEKEDKFDSIIKIGRTHLQDATPIKLGQEISGWRYMLDRCEIMLSESKKHILNLAIGGTAVGTGINAHPEFGDKVAHYISENTGYPFVSSENKFHALTAHDEVVQLHGTLKALAGDLMKIANDVRWLASGPRAGLAEISIPENEPGSSIMPGKVNPTQCEMLTMVAVQVMGNDTVVGFASSQGNFELNVYKPVIMHNTLQSIYLLADGMETFNNNCAVGIEPIEENIDNYLNQSLMLVTALNPHIGYEKAAQIAKKAHKEGLTLKESAIQTGYVTEEQFEAWIKPEDMVDPH
>NZ_CP017115.1|WP_000669376.1|1928520_1929342_+|RluA-family-pseudouridine-synthase
MKFKIPENFNDLSLRDIFQQLKVPKKDLHHLNMSKDITINDKPARLMDKVHTGDDVFVPTIDEKSNYVPSYRYAQIKYEDDDMAIVMKPKGVKTHPNDLKESNTLMNHVIYTIDSDYVEPIHRLDQETVGLLIVAKNPLMKKILDRMLEDNDITRIYKANVKALLPLKPQTIDMPIGKDKFHSNKRRVSPTGQRAITHILTSKMIKEAVCQLEIKLDTGRTHQIRVHLAEIGHPVIGDPLYGDSTLRQLELESYKIEFVHPLTKEVISVSLDD
>NZ_CP017115.1|WP_000110011.1|1947424_1947871_-|peroxide-responsive-transcriptional-repressor-PerR
MSVEIESIEHELEESIASLRQAGVRITPQRQAILRYLISSHTHPTADEIYQALSPDFPNISVATIYNNLRVFKDIGIVKELTYGDSSSRFDFNTHNHYHIICEQCGKIVDFQYPQLNEIERLAQHMTDFDVTHHRMEIYGVCKECQDK
>NZ_CP017115.1|WP_000869444.1|1947967_1948918_-|2-hydroxyacid-dehydrogenase
MKVVGLNRMREVETELQQRFSDLDFKFYKKASEIPESDLADLDILVGYDGGINEAFLQRCPNLKWIAWFATGVNTLPLDYIADHGILLTNGKGVQAKQLSEYILAFILDDYKKMKLSYDNQRQHIYDSKITGKRLSGQTVLFLGTGAIATRTAKLAKAFNMNLIGLSKSGQNKDEFDEIYTIESLESTLPNADIIINALPETQETIHLLKKKHFELMKDEALFINIGRGSIVKEALLIEVLKSKVIRHAYLDVFENEPLKPNHELYELDNVTITAHITGNDYEAKYDLLDIFKNNLVNFLNKNDLIENEVDAKKGY
>NZ_CP017115.1|WP_000939521.1|1948923_1949379_-|thioredoxin-dependent-thiol-peroxidase
MLQKGEQFPIFKLENQDGTVITNDTLKGKKAIIYFYPRDNTPTCTTEACDFRDNLEMFNDLDVAVYGISGDSKKKHQNFIEKHGLNFDLLVDEDFKLAKETGVYQLKKSFGKESMGIVRTTFIIDEQGKVLDVIEKVKVKTQIEELKNILG
>NZ_CP017115.1|WP_001011599.1|1949459_1950749_+|glutamate-1-semialdehyde-2,1-aminomutase
MNFSESERLQQLSNEYILGGVNSPSRSYKAVGGGAPVVMKEGHGAYLYDVDGNKFIDYLQAYGPIITGHAHPHITKAIQEQAAKGVLFGTPTELEIEFSKKLRDAIPSLEKIRFVNSGTEAVMTTIRVARAYTKRNKIIKFAGSYHGHSDLVLVAAGSGPSQLGSPDSAGVPESVAREVITVPFNDINAYKEAIEFWGDEIAAVLVEPIVGNFGMVMPQPGFLEEVNEISHNNGTLVIYDEVITAFRFHYGAAQDLLGVIPDLTAFGKIVGGGLPIGGYGGRQDIMEQVAPLGPAYQAGTMAGNPLSMKAGIALLEVLEQDGVYEKLDSLGQQLEEGLLKLIEKHNITATINRIYGSLTLYFTDEKVTHYDQVEHSDGEAFGKFFKLMLNQGINLAPSKFEAWFLTTEHTEEDIQQTLKAADYAFSQMK
>NZ_CP017115.1|WP_001236371.1|1951041_1952136_+|aromatic-acid-exporter-family-protein
MRLGARIFKTGIAIILAMSIASLLPDDVGLKALAGVSAVVAMQPSIYRSFKTVSDQALGNIIGAILSVTMVTIFSDNFIIMGVTVIVLIAILFKFNLAHVATLASVTALIIMGQHTGSFYITAFYRFVLVMIGVISSSLVNFVFLPPKFETKIYYNSLNISSDIFMWFKLVLNDTTEFNNIKQDSHNLKQRVEKLEKIYDYYSEERPITKKHIHQQNRKKILFREVVQTTRQAYEVLNKLSRYQNDLYLLNNNFLLQIKLDLDSLTAFHEQILASLSKKARYNVTHVDYELDNPQKKDLLSTFQHELINHPYQTEYSFANVMQIVAAIEEYRHHLEHLDRIRISFFTYHRSDADIEIVEEDFDL
>NZ_CP017115.1|WP_000597238.1|1952327_1954064_-|SAV1866-family-putative-multidrug-efflux-ABC-transporter
MIKRYLQFVKPYKYRIFATIIVGIIKFGIPMLIPLLIKYAIDGVINNHALTTDEKVHHLTIAIGIALFIFVIVRPPIEFIRQYLAQWTSNKILYDIRKKLYNHLQALSARFYANNQVGQVISRVINDVEQTKDFILTGLMNIWLDCITIIIALSIMFFLDVKLTLAALFIFPFYILTVYVFFGRLRKLTRERSQALAEVQGFLHERVQGISVVKSFAIEDNEAKNFDKKNTNFLTRALKHTRWNAYSFAAINTVTDIGPIIVIGVGAYLAISGSITVGTLAAFVGYLELLFGPLRRLVASFTTLTQSFASMDRVFQLIDEDYDIKNGVGAQPIEIKQGRIDIDHVSFQYNDNEAPILKDINLSIEKGETVAFVGMSGGGKSTLINLIPRFYDVTSGQILIDGHNIKDFLTGSLRNQIGLVQQDNILFSDTVKENILLGRPTATDEEVVEAAKMANAHDFIMNLPQGYDTEVGERGVKLSGGQKQRLSIARIFLNNPPILILDEATSALDLESESIIQEALDVLSKDRTTLIVAHRLSTITHADKIVVIENGHIVETGTHRELIAKQGAYEHLYSIQNL
>NZ_CP017115.1|WP_000251255.1|1954354_1954897_-|DUF402-domain-containing-protein
MVRESIPKEGENIKIQSYKHDGKIHRVWSETTILKGTDHVVIGGNDHTLVTESDGRTWITREPAIVYFHSEYWFNVICMFREDGIYYYCNLSSPFVCDEEALKYIDYDLDIKVYPNGKYHLLDEDEYEQHMNQMNYPHDIDIILRRNVDILQQWIEQKKGPFAPDFIKVWNERYKKIRQY
>NZ_CP017115.1|WP_000284760.1|1955198_1956236_-|A/G-specific-adenine-glycosylase
MYQQSSFKENLIHWFDENQREMPWRQTTNPYYIWLSEVMLQQTQVKTVIDYYHRFVERFPTVEVLSQASEDEVLKYWEGLGYYSRARNFHTAIKEVYDKYEGLVPKDPDQFKALKGVGPYTQAAVMSIAYNVPLATVDGNVFRVWSRLNDDYRDIKLQSTRKSYEQELLPYVTTEAGTFNQAMMELGALICTPKNPLCLFCPVQENCEAFDKGTFEKLPVKSKNVSKKVIEQSVFLIRNNQGQYLLQKRREKLLHGMWQFPMFESEHARRKMTEKIGHDIQPVETPIFELKHQFTHLTWKIKVYAVSGAINIETLPDDMIWFDLSDRDQYTFPVPMSKIYQFING
>NZ_CP017115.1|WP_000379098.1|1956387_1957365_+|metal-dependent-hydrolase
MDTATHIAIGVGLTALATQDPAMASTFGATATTLIVGSLIPDGDTVLKLKDNATYISHHRGITHSIPFTILWPILITFLIFTFFSGTNPFHVWMWAQLAVFLHVFVDIFNSYGTQALRPITNKWIQLSVINTFDPIIFTVLCIGIVLWVIGLHPFAVFFPIIALLIIYYMIRFKMRAVIKQQALKAIQQEHHPVKVFVAPTIKFMEWRVAIQTDAHDYVGKAYGRNVVFSDKVERQTLSTDSILWKVKGNKDIRTFLNFSSIYRWQTTTLADGSTEIRLIDLRYLKNDHYSFVAIAHVTNDNVIDHSYIGWVFTEDKLQRKLYAK
>NZ_CP017115.1|WP_000886468.1|1957625_1958462_-|membrane-protein
MLDNIILYFKNLPHTKRYVTERLKQSWKSFLIVLAACLILIIASETLFSFSHLTDVKEVRWLFRIIVLIVFAVVMFTIYISYHHYMNDFLVTKLFNISAATPVVIMSILSFIMLVILTMISALVKPVNFETSYIALFYFIVMATIFVGLISVTFGLIRLLTEKINIIFYGVCVLCFLLLPIIFIPNPNHVFINHILMLNPMYYIVNGIAQSIIFGISSMENIPYHFYFILFLCLIAAVNFVLARYTTHAIYNKTSKVTQTDNQQDVSNDSTDEADTSS

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Crispr_ID: NZ_CP017115_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017115_9

2210837-2210917

Orphan

Consensus_repeat	Method
CAACTTTAGTTGTTAGGGGCTCTT	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NZ_CP017115_9

>merge|NZ_CP017115|9|2210837-2210917|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTCAACTTTAGTTGTTAGGGGCTTCT

>NZ_CP017115|9|9|2210837-2210917|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTT	ATGCATGCGCTTAGCGCAGGCGCTCCTACTTTT
CAACTTTAGTTGTTAGGGGCTTCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017115.1\|WP_001024095.1\|2207343_2208009_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
NZ_CP017115.1\|WP_000908178.1\|2213778_2214561_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_CP017115.1\|WP_000019743.1\|2208482_2209463_+\|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl\|CDD\|224151
NZ_CP017115.1\|WP_001292149.1\|2220995_2221430_+\|mannitol-specific-phosphotransferase-enzyme-IIA-component	unknown	unknown	gnl\|CDD\|227014
NZ_CP017115.1\|WP_000123402.1\|2203663_2205037_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
NZ_CP017115.1\|WP_001123300.1\|2202792_2203206_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NZ_CP017115.1\|WP_000648723.1\|2221429_2222536_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_CP017115.1\|WP_001792784.1\|2212036_2212195_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_000927361.1\|2218851_2220984_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP017115.1\|WP_000370917.1\|2212853_2213711_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_CP017115.1\|WP_000808817.1\|2205708_2205939_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_000495683.1\|2209728_2210820_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_001127960.1\|2205969_2206908_-\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
NZ_CP017115.1\|WP_000070866.1\|2202149_2202593_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
NZ_CP017115.1\|WP_000003759.1\|2208160_2208481_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP017115.1\|WP_088607402.1\|2217278_2218817_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP017115.1\|WP_000160304.1\|2201318_2202029_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NZ_CP017115.1\|WP_000334465.1\|2214792_2216598_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP017115.1\|WP_001802298.1\|2211252_2211357_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_000521495.1\|2230646_2232002_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670

Protein	Function_ID	Function_description	E-value
NZ_CP017115.1\|WP_001024095.1\|2207343_2208009_-\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.27122e-47
NZ_CP017115.1\|WP_000908178.1\|2213778_2214561_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	9.14849e-105
NZ_CP017115.1\|WP_000019743.1\|2208482_2209463_+\|CDF-family-zinc-efflux-transporter-CzrB	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.20197e-108
NZ_CP017115.1\|WP_001292149.1\|2220995_2221430_+\|mannitol-specific-phosphotransferase-enzyme-IIA-component	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_CP017115.1\|WP_000334465.1\|2214792_2216598_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP017115.1\|WP_001123300.1\|2202792_2203206_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	4.46591e-45
NZ_CP017115.1\|WP_000648723.1\|2221429_2222536_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_CP017115.1\|WP_000123402.1\|2203663_2205037_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
NZ_CP017115.1\|WP_000927361.1\|2218851_2220984_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	1.10767e-67
NZ_CP017115.1\|WP_000370917.1\|2212853_2213711_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	7.97122e-60
NZ_CP017115.1\|WP_001127960.1\|2205969_2206908_-\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
NZ_CP017115.1\|WP_000070866.1\|2202149_2202593_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
NZ_CP017115.1\|WP_000003759.1\|2208160_2208481_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
NZ_CP017115.1\|WP_088607402.1\|2217278_2218817_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_CP017115.1\|WP_000160304.1\|2201318_2202029_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
NZ_CP017115.1\|WP_000521495.1\|2230646_2232002_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0

>NZ_CP017115.1|WP_000495683.1|2209728_2210820_+|hypothetical-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYVQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPVFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>NZ_CP017115.1|WP_000019743.1|2208482_2209463_+|CDF-family-zinc-efflux-transporter-CzrB
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHAH
>NZ_CP017115.1|WP_000003759.1|2208160_2208481_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>NZ_CP017115.1|WP_001024095.1|2207343_2208009_-|SDR-family-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGEQDIKDALTQFEIEKD
>NZ_CP017115.1|WP_001127960.1|2205969_2206908_-|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>NZ_CP017115.1|WP_000808817.1|2205708_2205939_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>NZ_CP017115.1|WP_000123402.1|2203663_2205037_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>NZ_CP017115.1|WP_001123300.1|2202792_2203206_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDCIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>NZ_CP017115.1|WP_000070866.1|2202149_2202593_-|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>NZ_CP017115.1|WP_000160304.1|2201318_2202029_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>NZ_CP017115.1|WP_001802298.1|2211252_2211357_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NZ_CP017115.1|WP_001792784.1|2212036_2212195_+|hypothetical-protein
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>NZ_CP017115.1|WP_000370917.1|2212853_2213711_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASPYTKDVINRLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>NZ_CP017115.1|WP_000908178.1|2213778_2214561_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKKISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATSGTVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDEEVRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPMLAMIYVTHFIEEITSNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_CP017115.1|WP_000334465.1|2214792_2216598_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_CP017115.1|WP_088607402.1|2217278_2218817_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNISETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_CP017115.1|WP_000927361.1|2218851_2220984_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDIDGNTSFENEQTSYLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDAINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMVLITVLEEPLILPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NZ_CP017115.1|WP_001292149.1|2220995_2221430_+|mannitol-specific-phosphotransferase-enzyme-IIA-component
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_CP017115.1|WP_000648723.1|2221429_2222536_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NZ_CP017115.1|WP_000521495.1|2230646_2232002_-|phosphoglucosamine-mutase
MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK

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Crispr_ID: NZ_CP017115_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017115_10

2223159-2223245

Orphan

Consensus_repeat	Method
GCCAACTGATGTTTGCGTATCATTAGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP017115_10

>merge|NZ_CP017115|10|2223159-2223245|CRISPRCasFinder
GCCAACTGATGTTTGCGTATCATTAGTTTGCATATCTTTAGCTTTATTGTTTGCAACTGAGCCAACTGATGTTTGCATATCATTAGT

>NZ_CP017115|10|10|2223159-2223245|CRISPRCasFinder
GCCAACTGATGTTTGCGTATCATTAGT	TTGCATATCTTTAGCTTTATTGTTTGCAACTGA
GCCAACTGATGTTTGCATATCATTAGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017115.1\|WP_000334465.1\|2214792_2216598_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP017115.1\|WP_000894032.1\|2232028_2232961_-\|YbbR-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|227193
NZ_CP017115.1\|WP_000347896.1\|2232962_2233772_-\|TIGR00159-family-protein	unknown	unknown	gnl\|CDD\|224539
NZ_CP017115.1\|WP_000958531.1\|2241064_2242129_-\|P-loop-NTPase	unknown	unknown	gnl\|CDD\|378455
NZ_CP017115.1\|WP_001292149.1\|2220995_2221430_+\|mannitol-specific-phosphotransferase-enzyme-IIA-component	unknown	unknown	gnl\|CDD\|227014
NZ_CP017115.1\|WP_088607403.1\|2242276_2243719_-\|multidrug-efflux-MFS-transporter-LmrS	unknown	unknown	gnl\|CDD\|129794
NZ_CP017115.1\|WP_000908178.1\|2213778_2214561_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_CP017115.1\|WP_001793373.1\|2244041_2244515_-\|multidrug-efflux-transporter-SepA	unknown	unknown	gnl\|CDD\|374975
NZ_CP017115.1\|WP_000884735.1\|2246835_2248023_-\|UDPGP-type-1-family-protein	unknown	unknown	gnl\|CDD\|133036
NZ_CP017115.1\|WP_000648723.1\|2221429_2222536_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_CP017115.1\|WP_001792784.1\|2212036_2212195_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_000370917.1\|2212853_2213711_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_CP017115.1\|WP_001237503.1\|2244613_2245957_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP017115.1\|WP_000927361.1\|2218851_2220984_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP017115.1\|WP_000167873.1\|2233960_2234869_-\|arginase	unknown	unknown	gnl\|CDD\|212515
NZ_CP017115.1\|WP_000047255.1\|2246133_2246817_-\|hemolysin-III-family-protein	unknown	unknown	gnl\|CDD\|224191
NZ_CP017115.1\|WP_000495683.1\|2209728_2210820_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_088607402.1\|2217278_2218817_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP017115.1\|WP_001802298.1\|2211252_2211357_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_000521495.1\|2230646_2232002_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670

Protein	Function_ID	Function_description	E-value
NZ_CP017115.1\|WP_000334465.1\|2214792_2216598_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP017115.1\|WP_000894032.1\|2232028_2232961_-\|YbbR-like-domain-containing-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	6.26423e-118
NZ_CP017115.1\|WP_000347896.1\|2232962_2233772_-\|TIGR00159-family-protein	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	2.13611e-103
NZ_CP017115.1\|WP_000958531.1\|2241064_2242129_-\|P-loop-NTPase	gnl\|CDD\|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	6.43129e-115
NZ_CP017115.1\|WP_001292149.1\|2220995_2221430_+\|mannitol-specific-phosphotransferase-enzyme-IIA-component	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_CP017115.1\|WP_088607403.1\|2242276_2243719_-\|multidrug-efflux-MFS-transporter-LmrS	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.95689e-81
NZ_CP017115.1\|WP_000908178.1\|2213778_2214561_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	9.14849e-105
NZ_CP017115.1\|WP_001237503.1\|2244613_2245957_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	2.27036e-43
NZ_CP017115.1\|WP_000884735.1\|2246835_2248023_-\|UDPGP-type-1-family-protein	gnl\|CDD\|133036	cd04193, UDPGlcNAc_PPase, UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc) pyrophosphorylase (UAP) (also named GlcNAc1P uridyltransferase), catalyzes the reversible conversion of UTP and GlcNAc1 to PPi and UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc), the activated form of GlcNAc, is a key precursor of N- and O-linked glycosylations. It is essential for the synthesis of chitin (a major component of the fungal cell wall) and of the glycosylphosphatidylinositol (GPI) linker which anchors a variety of cell surface proteins to the plasma membrane. In bacteria, UDPGlcNAc represents an essential precursor for both peptidoglycan and lipopolysaccharide biosynthesis. Human UAP has two isoforms, resulting from alternative splicing of a single gene and differing by the presence or absence of 17 amino acids. UDPGlcNAc pyrophosphorylase shares significant sequence and structure conservation with UDPglucose pyrophosphorylase.	2.43588e-149
NZ_CP017115.1\|WP_000648723.1\|2221429_2222536_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_CP017115.1\|WP_000370917.1\|2212853_2213711_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	7.97122e-60
NZ_CP017115.1\|WP_000927361.1\|2218851_2220984_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	1.10767e-67
NZ_CP017115.1\|WP_000167873.1\|2233960_2234869_-\|arginase	gnl\|CDD\|212515	cd09989, Arginase, Arginase family. This family includes arginase, also known as arginase-like amidino hydrolase family, and related proteins. Arginase is a binuclear Mn-dependent metalloenzyme and catalyzes hydrolysis of L-arginine to L-ornithine and urea (Arg, EC 3.5.3.1), the reaction being the fifth and final step in the urea cycle, providing the path for the disposal of nitrogenous compounds. Arginase controls cellular levels of arginine and ornithine which are involved in protein biosynthesis, and in production of creatine, polyamines, proline and nitric acid. In vertebrates, at least two isozymes have been identified: type I (ARG1) cytoplasmic or hepatic liver-type arginase and type II (ARG2) mitochondrial or non-hepatic arginase. Point mutations in human arginase ARG1 gene lead to hyperargininemia with consequent mental disorders, retarded development and early death. Hyperargininemia is associated with a several-fold increase in the activity of the mitochondrial arginase (ARG2), causing persistent ureagenesis in patients. ARG2 overexpression plays a critical role in the pathophysiology of cholesterol mediated endothelial dysfunction. Thus, arginase is a therapeutic target to treat asthma, erectile dysfunction, atherosclerosis and cancer.	6.64002e-146
NZ_CP017115.1\|WP_000047255.1\|2246133_2246817_-\|hemolysin-III-family-protein	gnl\|CDD\|224191	COG1272, COG1272, Predicted membrane protein, hemolysin III homolog [General function prediction only].	2.41003e-66
NZ_CP017115.1\|WP_088607402.1\|2217278_2218817_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_CP017115.1\|WP_001793373.1\|2244041_2244515_-\|multidrug-efflux-transporter-SepA	gnl\|CDD\|374975	pfam17080, SepA, Multidrug Resistance efflux pump. SepA is a drug efflux protein that is involved in bacterial multidrug resistance. It is predicted to have four transmembrane domains.	3.24535e-30
NZ_CP017115.1\|WP_000521495.1\|2230646_2232002_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0

>NZ_CP017115.1|WP_000648723.1|2221429_2222536_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NZ_CP017115.1|WP_001292149.1|2220995_2221430_+|mannitol-specific-phosphotransferase-enzyme-IIA-component
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_CP017115.1|WP_000927361.1|2218851_2220984_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDIDGNTSFENEQTSYLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDAINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMVLITVLEEPLILPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NZ_CP017115.1|WP_088607402.1|2217278_2218817_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNISETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_CP017115.1|WP_000334465.1|2214792_2216598_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_CP017115.1|WP_000908178.1|2213778_2214561_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKKISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATSGTVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDEEVRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPMLAMIYVTHFIEEITSNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_CP017115.1|WP_000370917.1|2212853_2213711_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASPYTKDVINRLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>NZ_CP017115.1|WP_001792784.1|2212036_2212195_+|hypothetical-protein
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>NZ_CP017115.1|WP_001802298.1|2211252_2211357_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NZ_CP017115.1|WP_000495683.1|2209728_2210820_+|hypothetical-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYVQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPVFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>NZ_CP017115.1|WP_000521495.1|2230646_2232002_-|phosphoglucosamine-mutase
MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
>NZ_CP017115.1|WP_000894032.1|2232028_2232961_-|YbbR-like-domain-containing-protein
MLESKWGLRFIAFLLALFFFLSVNNVFGNIFNTGNLGQKSSKTIQDVPVEILYNTKDLHLTKAPETVNVTISGPQSKIIKIENPEDLRVVIDLSNAKAGKYQEKYQVKGLADDIHYSVKPKLANITLENKVTKKMTVQPDVSQSDIDPLYKITKQEVSPQTVKVTGGEEQLNDIAYLKATFKTNKKINGDTKDVAEVTAFDKKLNKLNVSIQPNEVNLQVKVEPFSKKVKVNVKQKGSLADDKELSSIDLEDKEIEIFGSRDDLQNISEVDAEVDLDGISESTEKTVKINLPEHVTKAQPSETKAYINVK
>NZ_CP017115.1|WP_000347896.1|2232962_2233772_-|TIGR00159-family-protein
MDFSNFFQNLSTLKIVTSILDLLIVWYVLYLLITVFKGTKAIQLLKGILVIVIGQQISMILNLTATSKLFDIVIQWGVLALIVIFQPEIRRALEQLGRGSFLKRYTSNTYSKDEEKLIQSVSKAVQYMAKRRIGALIVFEKETGLQDYIETGIAMDSNISQELLINVFIPNTPLHDGAMIIQGTKIAAAASYLPLSDSPKISKSLGTRHRAAVGISEVSDAFTVIVSEETGDISVTFDGKLRRDISNEIFEELLAEHWFGTRFQKKGVK
>NZ_CP017115.1|WP_000167873.1|2233960_2234869_-|arginase
MTKTKAIDIIGAPSTFGQRKLGVDLGPTAIRYAGLISRLKQLDLDVYDKGDIKVPVVNIEKFHSEQKGLRNYDEIIDVNQKLNKEVSASIENNRFPLVLGGDHSIAVGSVSAISKHYNNLGVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLELNSNVIKPENIVLIGMRDLDKGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKSRNVDGVHLSLDVDALDPLETPGTGTRVLGGLSYRESHFALELLHQSHLISSMDLVEVNPLIDSNNHTAEQAVSLVGTFFGETLL
>NZ_CP017115.1|WP_000958531.1|2241064_2242129_-|P-loop-NTPase
MLTVDQVKELVGEIKDPIIDVPLKETEGIVEVSIKEEKEHVSVKLAMAQLGGAPQLDLQMAVVNALKENGAKTVGIRFETLPEEKVNQFKPKEENKPKTIEGLLSQNNPVEFIAIASGKGGVGKSTVAVNLAVALAREGKKVGLVDADIYGFSVPDMMGIDEKPGIKGKEVIPVERHGVKVISMAFFVEENAPVIWRGPMLGKMLTNFFTEVKWGDIEYLILDLPPGTGDVALDVHTMLPSSKEIIVTTPHPTAAFVAARAGAMAKHTDHSILGVIENMSYFESKETGNKEYVFGKGGGTKLADELNTQLLGELPLEQPSWNPKDFAPSIYQSDDRLGKIYSSIAQKVIAATNK
>NZ_CP017115.1|WP_088607403.1|2242276_2243719_-|multidrug-efflux-MFS-transporter-LmrS
MAKVELTTRRRNFIVAVMLISAFVAILNQTLLNTALPSIMRELNINESTSQWLVTGFMLVNGVMIPLTAYLMDRIKTRPLYLAAMGTFLLGSIVAALAPNFGVLMLARVIQAMGAGVLMPLMQFTLFTLFSKEHRGFAMGLAGLVIQFAPAIGPTVTGLIIDQASWRVPFIIIVGIALVAFVFGLVSISSYNEVKYTKLDKRSVMYSTIGFGLMLYAFSSAGDLGFTSPIVIGALIISMVIIYLFIRRQFNITNALLNLRVFKNRTFALCTISSMIIMMSMVGLALLIPLYVQNSLSLSALLSGLVIMPGAIINGIMSVFTGKFYDKYGPRPLIYTGFTILTITTIMLCFLHTDTSYTYLIVVYAIRMFSVSLLMMPINTTGINSLRNEEISHGTAIMNFGRVMAGSLGTALMVTLMSFGAKIFLSTSPSHLTATEIKQQSIAIGVDISFAFVAVLVMAAYVIALFIREPKEIESNRRKF
>NZ_CP017115.1|WP_001793373.1|2244041_2244515_-|multidrug-efflux-transporter-SepA
MIVNYLKHKFYNLLTTMVVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIIFAVEHLMDYFRKMLPENAYFRGATFHLISYTVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
>NZ_CP017115.1|WP_001237503.1|2244613_2245957_-|MFS-transporter
MRLKSIITVIALILIMFMSAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPIVGELLSRFKIIYVAIAGLLLFSIGSFMCGLSTNFTMLIISRVIQGFGSGVLMSLSQIVPKLAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWHWLFYINIPIAIIAIILVIWTFHFPEEETVAKSKFDTKGLTLFYVFIGLIMFALLNQQLLLLNFLSFILAIVVAMCLFKVEKHVSSPFLPVVEFNRSITLVFITDLLTAICLMGFNLYIPVYLQEQLGLSPLQSGLVIFPLSLAWITLNFNLHRIEAKLSRKVIYLLSFTLLLVSSIIISFGIKLPVLIAFVLILAGLSFGYIYTKDSVIVQEETSPLQMKKMMSFYGLTKNLGASIGSTIMGYLYAIQSGIFGPNLHNVLSAVAVISIGLIVLWVVFFKEQSSQSKE
>NZ_CP017115.1|WP_000047255.1|2246133_2246817_-|hemolysin-III-family-protein
MSKSTKKSNDTIVETFKDIIPLSFGEEIGNAASHGVAALLTLLVLPYAAVHSYIAHGTLASVSMSIYVISIFMMFISSTIYHSMQNETPHKYILRIIDHSMIYVAISGTYTPILLTVVGGWIGWTVFILLWGTTLWGILYKSIAVKVNQKLSLIVYLVMGWVGIILLPIIFIRTSWIFILFIFLGGVSYTIGAWFYAQKNRPYFHMIWHIFIVIASLLHLIAILYFM
>NZ_CP017115.1|WP_000884735.1|2246835_2248023_-|UDPGP-type-1-family-protein
MLDKNQLAKYKQDHLCEYEKIMSNNEKEALEEKVASLDLDFIAKLYNDLYINKKTIDDVSAVSEVKYDIKSQMSDDEIKRLEEQGLQAIKEGQFAVLLMAGGQGTRLGYKGPKGSFEIEGVSLFELQANQLKTLNHQSGHTIQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMETPNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVKVLDPLFAGFTVEHDYDITSKTIQPKPGESVGRLVNVDCKDTVLEYSELDPEVANQFNNANIGIHAFKLGFILNAVNRELPYHLAIKNLKQLDENFGVIEQPTLKFELFYFDIFTYGTSFVTLQVPREEEFSPLKNKEGKDSVATATEDLRRMGLI

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Crispr_ID: NZ_CP017115_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017115_11

2322345-2322430

Orphan

Consensus_repeat	Method
CCAACTTGCACATTATTGTAAGCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP017115_11

>merge|NZ_CP017115|11|2322345-2322430|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTTTCGTCACCTTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTT

>NZ_CP017115|11|11|2322345-2322430|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTT	TCGTCACCTTCTATGTTGGGGCCCCG
CCAACTTGCACATTATTGTAAGCTGACTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017115.1\|WP_000051210.1\|2312916_2313081_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_000951060.1\|2319933_2320374_+\|winged-helix-DNA-binding-protein	unknown	unknown	gnl\|CDD\|197670
NZ_CP017115.1\|WP_000602937.1\|2324954_2325440_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
NZ_CP017115.1\|WP_000184413.1\|2320366_2321578_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NZ_CP017115.1\|WP_000134536.1\|2326758_2327253_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NZ_CP017115.1\|WP_000066900.1\|2321679_2322030_-\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
NZ_CP017115.1\|WP_001790034.1\|2322155_2322326_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_000503820.1\|2327254_2327761_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	unknown	unknown	gnl\|CDD\|223595
NZ_CP017115.1\|WP_000592298.1\|2313826_2316994_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NZ_CP017115.1\|WP_000600973.1\|2319007_2319772_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
NZ_CP017115.1\|WP_000230173.1\|2322607_2323630_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NZ_CP017115.1\|WP_000643988.1\|2323649_2324249_-\|molybdenum-cofactor-guanylyltransferase-MobA	unknown	unknown	gnl\|CDD\|234725
NZ_CP017115.1\|WP_000259724.1\|2325436_2326696_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NZ_CP017115.1\|WP_000866971.1\|2324255_2324489_-\|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl\|CDD\|340452
NZ_CP017115.1\|WP_001161082.1\|2313325_2313643_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_000413863.1\|2317110_2318376_-\|lipid-II:glycine-glycyltransferase-FemX	unknown	unknown	gnl\|CDD\|225224
NZ_CP017115.1\|WP_000913019.1\|2328965_2329571_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226628
NZ_CP017115.1\|WP_001566779.1\|2318764_2319016_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_000808500.1\|2324494_2324941_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|223391
NZ_CP017115.1\|WP_000076923.1\|2327791_2328796_-\|molybdopterin-biosynthesis-protein-MoeB	unknown	unknown	gnl\|CDD\|181084

Protein	Function_ID	Function_description	E-value
NZ_CP017115.1\|WP_000413863.1\|2317110_2318376_-\|lipid-II:glycine-glycyltransferase-FemX	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	3.69463e-143
NZ_CP017115.1\|WP_000602937.1\|2324954_2325440_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	4.35501e-50
NZ_CP017115.1\|WP_000184413.1\|2320366_2321578_+\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.54033e-72
NZ_CP017115.1\|WP_000134536.1\|2326758_2327253_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	9.25584e-98
NZ_CP017115.1\|WP_000066900.1\|2321679_2322030_-\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
NZ_CP017115.1\|WP_000643988.1\|2323649_2324249_-\|molybdenum-cofactor-guanylyltransferase-MobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	5.68918e-67
NZ_CP017115.1\|WP_000592298.1\|2313826_2316994_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NZ_CP017115.1\|WP_000076923.1\|2327791_2328796_-\|molybdopterin-biosynthesis-protein-MoeB	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	3.23825e-132
NZ_CP017115.1\|WP_000230173.1\|2322607_2323630_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
NZ_CP017115.1\|WP_000808500.1\|2324494_2324941_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.56799e-58
NZ_CP017115.1\|WP_000866971.1\|2324255_2324489_-\|molybdopterin-converting-factor-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	8.16473e-25
NZ_CP017115.1\|WP_000600973.1\|2319007_2319772_-\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	4.64519e-37
NZ_CP017115.1\|WP_000951060.1\|2319933_2320374_+\|winged-helix-DNA-binding-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.28933e-15
NZ_CP017115.1\|WP_000913019.1\|2328965_2329571_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	3.32197e-115
NZ_CP017115.1\|WP_000503820.1\|2327254_2327761_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	9.7838e-65
NZ_CP017115.1\|WP_000259724.1\|2325436_2326696_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	6.35078e-159

>NZ_CP017115.1|WP_001790034.1|2322155_2322326_+|hypothetical-protein
MFRFISFGQLVVYSTTFIPKKDILQLNGMECDINVKEPLKIYYVVILKSGIEMIFS
>NZ_CP017115.1|WP_000066900.1|2321679_2322030_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>NZ_CP017115.1|WP_000184413.1|2320366_2321578_+|MFS-transporter
MTNQGSLNKSPIFTKSFTINFFVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYPIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>NZ_CP017115.1|WP_000951060.1|2319933_2320374_+|winged-helix-DNA-binding-protein
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHKILLKETHND
>NZ_CP017115.1|WP_000600973.1|2319007_2319772_-|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNNIEAVKNKLQSERVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>NZ_CP017115.1|WP_001566779.1|2318764_2319016_+|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLAIIHMGILAHSTYVYLY
>NZ_CP017115.1|WP_000413863.1|2317110_2318376_-|lipid-II:glycine-glycyltransferase-FemX
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>NZ_CP017115.1|WP_000592298.1|2313826_2316994_-|efflux-RND-transporter-permease-subunit
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTFAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASAPNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVVTIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGNIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>NZ_CP017115.1|WP_001161082.1|2313325_2313643_+|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTMMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>NZ_CP017115.1|WP_000051210.1|2312916_2313081_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDLEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>NZ_CP017115.1|WP_000230173.1|2322607_2323630_-|GTP-3',8-cyclase-MoaA
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>NZ_CP017115.1|WP_000643988.1|2323649_2324249_-|molybdenum-cofactor-guanylyltransferase-MobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>NZ_CP017115.1|WP_000866971.1|2324255_2324489_-|molybdopterin-converting-factor-subunit-1
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>NZ_CP017115.1|WP_000808500.1|2324494_2324941_-|molybdenum-cofactor-biosynthesis-protein-MoaE
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>NZ_CP017115.1|WP_000602937.1|2324954_2325440_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRNEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>NZ_CP017115.1|WP_000259724.1|2325436_2326696_-|molybdopterin-molybdotransferase-MoeA
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETTTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFVDGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>NZ_CP017115.1|WP_000134536.1|2326758_2327253_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNKTIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSNQ
>NZ_CP017115.1|WP_000503820.1|2327254_2327761_-|molybdenum-cofactor-biosynthesis-protein-MoaB
MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>NZ_CP017115.1|WP_000076923.1|2327791_2328796_-|molybdopterin-biosynthesis-protein-MoeB
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWDGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>NZ_CP017115.1|WP_000913019.1|2328965_2329571_-|ATP-binding-cassette-domain-containing-protein
MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

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Crispr_ID: NZ_CP017115_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017115_12

2490588-2490666

Orphan

Consensus_repeat	Method
CCAACTTGCATTGTCTCTAGAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP017115_12

>merge|NZ_CP017115|12|2490588-2490666|CRISPRCasFinder
CCAACTTGCATTGTCTCTAGAAATTGGGAATCCAATTTCTCTTAGTTGGGACTCCGCCAACTTGCATTGTCTGTAGAAA

>NZ_CP017115|12|12|2490588-2490666|CRISPRCasFinder
CCAACTTGCATTGTCTCTAGAAA	TTGGGAATCCAATTTCTCTTAGTTGGGACTCCG
CCAACTTGCATTGTCTGTAGAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017115.1\|WP_088607410.1\|2488525_2490289_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP017115.1\|WP_000482647.1\|2490972_2491080_-\|type-I-toxin-antitoxin-system-Fst-family-toxin	unknown	unknown	unknown
NZ_CP017115.1\|WP_000456497.1\|2495234_2495708_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226231
NZ_CP017115.1\|WP_001217916.1\|2485628_2486315_-\|dethiobiotin-synthase	unknown	unknown	gnl\|CDD\|223210
NZ_CP017115.1\|WP_000831301.1\|2493059_2493719_+\|membrane-protein	unknown	unknown	gnl\|CDD\|222878
NZ_CP017115.1\|WP_001192075.1\|2493900_2495112_+\|multidrug-effflux-MFS-transporter	unknown	unknown	gnl\|CDD\|340878
NZ_CP017115.1\|WP_000286878.1\|2481487_2482180_-\|6-carboxyhexanoate--CoA-ligase	unknown	unknown	gnl\|CDD\|224342
NZ_CP017115.1\|WP_031928444.1\|2484292_2485651_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|273109
NZ_CP017115.1\|WP_001790576.1\|2486369_2486537_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_001176871.1\|2491857_2493000_+\|glycerate-kinase	unknown	unknown	gnl\|CDD\|272872
NZ_CP017115.1\|WP_001185692.1\|2499178_2501257_+\|sodium:proton-antiporter	unknown	unknown	gnl\|CDD\|223104
NZ_CP017115.1\|WP_000486494.1\|2486767_2488501_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP017115.1\|WP_000779360.1\|2491213_2491600_-\|GtrA-family-protein	unknown	unknown	gnl\|CDD\|225155
NZ_CP017115.1\|WP_001080281.1\|2495820_2496477_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227323
NZ_CP017115.1\|WP_000101538.1\|2497631_2499041_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NZ_CP017115.1\|WP_001046645.1\|2483283_2484291_-\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|235755
NZ_CP017115.1\|WP_000971548.1\|2482190_2483306_-\|pyridoxal-phosphate-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|223234
NZ_CP017115.1\|WP_000690199.1\|2496539_2497346_-\|phosphohydrolase	unknown	unknown	gnl\|CDD\|163441
NZ_CP017115.1\|WP_000200943.1\|2481009_2481477_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377623
NZ_CP017115.1\|WP_000783428.1\|2479980_2480958_+\|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B	unknown	unknown	gnl\|CDD\|273388

Protein	Function_ID	Function_description	E-value
NZ_CP017115.1\|WP_088607410.1\|2488525_2490289_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.42087e-146
NZ_CP017115.1\|WP_000101538.1\|2497631_2499041_+\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	0
NZ_CP017115.1\|WP_000456497.1\|2495234_2495708_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|226231	COG3708, COG3708, Uncharacterized protein conserved in bacteria [Function unknown].	2.01209e-37
NZ_CP017115.1\|WP_001217916.1\|2485628_2486315_-\|dethiobiotin-synthase	gnl\|CDD\|223210	COG0132, BioD, Dethiobiotin synthetase [Coenzyme metabolism].	1.45777e-70
NZ_CP017115.1\|WP_000831301.1\|2493059_2493719_+\|membrane-protein	gnl\|CDD\|222878	PHA02562, 46, endonuclease subunit; Provisional.	0.00700231
NZ_CP017115.1\|WP_001192075.1\|2493900_2495112_+\|multidrug-effflux-MFS-transporter	gnl\|CDD\|340878	cd17320, MFS_MdfA_MDR_like, Multidrug transporter MdfA and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as MdfA (also called chloramphenicol resistance pump Cmr), EmrD, MdtM, MdtL, bicyclomycin resistance protein (also called sulfonamide resistance protein), and the uncharacterized inner membrane transport protein YdhC. EmrD is a proton-dependent secondary transporter, first identified as an efflux pump for uncouplers of oxidative phosphorylation. It expels a range of drug molecules and amphipathic compounds across the inner membrane of E. coli. Similarly, MdfA is a secondary multidrug transporter that exports a broad spectrum of structurally and electrically dissimilar toxic compounds. These MDR transporters are drug/H+ antiporters (DHA) belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.81144e-73
NZ_CP017115.1\|WP_000286878.1\|2481487_2482180_-\|6-carboxyhexanoate--CoA-ligase	gnl\|CDD\|224342	COG1424, BioW, Pimeloyl-CoA synthetase [Coenzyme metabolism].	3.89049e-130
NZ_CP017115.1\|WP_031928444.1\|2484292_2485651_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl\|CDD\|273109	TIGR00508, hypothetical_protein_DESPIG_00326, adenosylmethionine-8-amino-7-oxononanoate transaminase. All members of the seed alignment have been demonstrated experimentally to act as EC 2.6.1.62, an enzyme in the biotin biosynthetic pathway. Alternate names include 7,8-diaminopelargonic acid aminotransferase, DAPA aminotransferase, and adenosylmethionine-8-amino-7-oxononanoate aminotransferase. The gene symbol is bioA in E. coli and BIO3 in S. cerevisiae. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	0
NZ_CP017115.1\|WP_001176871.1\|2491857_2493000_+\|glycerate-kinase	gnl\|CDD\|272872	TIGR00045, Glycerate_kinase, glycerate kinase. The only characterized member of this family so far is the glycerate kinase GlxK (EC 2.7.1.31) of E. coli. This enzyme acts after glyoxylate carboligase and 2-hydroxy-3-oxopropionate reductase (tartronate semialdehyde reductase) in the conversion of glyoxylate to 3-phosphoglycerate (the D-glycerate pathway) as a part of allantoin degradation. [Energy metabolism, Other].	0
NZ_CP017115.1\|WP_001185692.1\|2499178_2501257_+\|sodium:proton-antiporter	gnl\|CDD\|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	2.07656e-103
NZ_CP017115.1\|WP_000486494.1\|2486767_2488501_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	6.79158e-143
NZ_CP017115.1\|WP_000779360.1\|2491213_2491600_-\|GtrA-family-protein	gnl\|CDD\|225155	COG2246, COG2246, Predicted membrane protein [Function unknown].	1.41026e-22
NZ_CP017115.1\|WP_001080281.1\|2495820_2496477_+\|hypothetical-protein	gnl\|CDD\|227323	COG4990, COG4990, Uncharacterized protein conserved in bacteria [Function unknown].	2.51069e-72
NZ_CP017115.1\|WP_001046645.1\|2483283_2484291_-\|biotin-synthase-BioB	gnl\|CDD\|235755	PRK06256, PRK06256, biotin synthase; Validated.	0
NZ_CP017115.1\|WP_000971548.1\|2482190_2483306_-\|pyridoxal-phosphate-dependent-aminotransferase-family-protein	gnl\|CDD\|223234	COG0156, BioF, 7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism].	3.62949e-138
NZ_CP017115.1\|WP_000690199.1\|2496539_2497346_-\|phosphohydrolase	gnl\|CDD\|163441	TIGR03729, acc_ester, putative phosphoesterase. Members of this protein family belong to the larger family pfam00149 (calcineurin-like phosphoesterase), a family largely defined by small motifs of metal-chelating residues. The subfamily in this model shows a good but imperfect co-occurrence in species with domain TIGR03715 that defines a novel class of signal peptide typical of the accessory secretory system.	1.39132e-107
NZ_CP017115.1\|WP_000200943.1\|2481009_2481477_-\|hypothetical-protein	gnl\|CDD\|377623	pfam06177, QueT, QueT transporter. This family includes the queT gene encoding a hypothetical integral membrane protein with 5 predicted transmembrane regions. The queT genes in Firmicutes are often preceded by the PreQ1 (7-aminomethyl-7-deazaguanine) riboswitches of two distinct classes, suggesting involvement of the QueT transporters in uptake of a queuosine biosynthetic intermediate.	0.00179995
NZ_CP017115.1\|WP_000783428.1\|2479980_2480958_+\|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	5.50766e-128

>NZ_CP017115.1|WP_088607410.1|2488525_2490289_-|ABC-transporter-ATP-binding-protein
MNNQTNWIKILSGFASDSKWKIMLSILLSIISVFSGLVPYWAVFKIILMMINNAYTINSIMVYIFIALIAYISQVCCFGASTMLSHITAYEILSEIRKKLAQKLMRLPLGVVESKKIGELKNIFVDKVETIELSLAHMIPEVIGNLLLSAAIFLYIMLIDWRMASALLVTIPISIFAFKKVMSGFNETYAEQMKSNNYMNSAIVEFIEGIEVIKTFNQSQSSYKKYKDAVDNYKIHTLNWFKNTWGYMNLGASVLPSTFLGILPVGMYLISINQLNYAEFFLCIVLSLGVVAPIKNFTNYVNHLKSIQYALTEVNQILSLEELVLSTKFKKPQHYEIAFNNVGFSYNKDKDDLVFKHLSFTVPENNFTAIVGASGSGKSTIAKLISRYWDVTSGEITIGGINIKDIESKQLNDLVGFVGQDNFLLNLTFKENIKLGNPEATDEAVEKAAKLAQCHEFIEKLPDGYDTNVGTVGDKLSGGEKQRVTIARMILKDAPIIVLDEATAYVDPDNEQKIQEALNVLTQDKTLIVIAHRLSTIQHADQIIVLGKQQILEKGSHHLLLKLNGNYKKMWDTHMHTKDWGINTGHN
>NZ_CP017115.1|WP_000486494.1|2486767_2488501_-|ABC-transporter-ATP-binding-protein
MFQITFKILNWIRPYKARMILGFSMSFLNAIFIALPIFLAAKIFNNVLSHKPIYMKDILNVVIIMVLLVIGRFITAYFKSKSHESIAYEMSAKERLDIGDKLKNVRLGYFNSHHSNELTTIVTTDLTFLENFAMKMVDVVVNGYILITVLILSLLVVSWQVSLLACIGVLLSFFAIQLLERKSRQNAPAYHNVQNQLVEKVLEVIRGIQVIKSFAKENTSLKSFNQAVNESKRINTKIEMQYIPFNLLHLLSLKVVSIMIVLVACLLYMNHSIDLPTLIMISIFSFVIFDSVENINSAAHVLEMIDMTIDDIEKIKNAPELDENGKNLTIKNENIAFQNVNFSYDDKQVIKNVNFEIPTQTSTAIIGPSGSGKSTLCHLLLRFYDIDDGNIRIDGVDIKDMTLSTLMSKISAVFQKVYLFNDTIENNILFGNPGATKEEIIRAAKQACCHDFIMSLPEGYQTMLNEKGSNLSGGEKQRISIARAILKDAPIIILDEATASIDPENEQLIQTAINELSKGKTVITIAHKLETIKNADQIIVLNEGEIIQKGSHDELIRKPGMYQDFIRIKSKSAGWKL
>NZ_CP017115.1|WP_001790576.1|2486369_2486537_-|hypothetical-protein
MQLLILTDIFYRIAVYICPNSLRSLSHFNSKVKILPKFIVILRSLNSCFLEKHAP
>NZ_CP017115.1|WP_001217916.1|2485628_2486315_-|dethiobiotin-synthase
MRIFITSTNTDVGKTYVTKHLYHALKTRGHRVCIFKPFQTEERQDGTFPDLEVFKNECDLSYDITSLYTFKQPVSPHLAFKMTDQIFLNKQRVLDKVKVLDKEFDFILIEGAGGIAVPIYEGTDDFYMTKDLINDCADCVISVLPSKLGAISDAIVHQDYVNQNVSASNFLIMNRYTDSYIEKDNQITIGKLTNKTVYTFEEHATYENFSEAFLKQLIGVKNELHTTT
>NZ_CP017115.1|WP_031928444.1|2484292_2485651_-|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MNYTQQLKQKDSEYVWHPFTQMGVYSKEETIIIEKGKGSYLYDTNGNKYLDGYASLWVNVHGHNNKYLNKVIKKQLNKIAHSTLLGSSNIPSIELAEKLIEITPSNLRKVFYSDTGSASVEIAIKMAYQYWKNIDREKYAKKNKFITLNHGYHGDTIGAVSVGGIKTFHKIFKDLIFENIQVESPSFYRSNYDNENEMMTAILTNIEQILIERNDEIAGFILEPLIQGATGLFVHPKGFLKEVEKLCKKYDVLLICDEVAVGFGRTGKMFACNHEDVQPDIMCLGKAITGGYLPLAATLTSQKIYNAFLSDSHGVNTFFHGHTYTGNQIVCTVALENIRLYEKRKLLSHIETTSSTLEKQLHALKRHRNVGDVRGRGLMFGVELVTDKDSKTPLEIEKVERIVRKCKENGLMIRNLENVITFVPVLSMSNKEVKTMVRIFKKAVHNILDRKC
>NZ_CP017115.1|WP_001046645.1|2483283_2484291_-|biotin-synthase-BioB
MNLAKRILQGEQLTKETVLKIYEDTNIDTLDLLNEAYILRKHYFGKKVKLNMILNAKSGICPENCGYCGQSRDIKQKQRYALIPEEQIIDGAKVAHDNHIGTYCIVMSGRGPSDKEVDHISNTVRTIKSQHPQLKICACLGLTNDEQAKKLKSAGVDRYNHNINTSENYHDNVVTTHSYKDRTDTIELMKANNISPCSGVICGMGESNQDIVDMAFALKEMDADSIPINFLHPIKGTKFGSMDDLTPMKCLRIVALFRLINPTKEIRIAGGREVNLRSLQPLALKAANSIFVGDYLITGGQPNQLDYDMINDLGFEIDYDTCENKENKNDVSRAN
>NZ_CP017115.1|WP_000971548.1|2482190_2483306_-|pyridoxal-phosphate-dependent-aminotransferase-family-protein
MMFQEQIDLLQQKGLYRSLKSVGYIDRQYIEVENKRCTNYTSNDYLGLGQIAFDKDDFERFMRKYSYHLSSSRLISGSSTAYEEIETMLAGWLGYSACTILNSGYDANLALFNIFKNTNCVVFSDQENHASIIDGIKLSGLEKVIYKHLDIADLEKRLEKYPNQNIPKIIISDSAFSTNGDVVDIGQLVSLKHKYNATLILDVSHSFGIENYSNYQGVDILTSSLSKACGAYGGVILSSNDVKDMLINHGRPLIYSSSLPIYNLYFIKRNIEKLINADDRRTKLNSLSKYFNQKLKALNVNYNSSNSPIKFIEFDDIEAAENIHQTLLKHHVFTSYLRYPTVTKPMLRISLSYFHTEQDIDRLFEILHQED
>NZ_CP017115.1|WP_000286878.1|2481487_2482180_-|6-carboxyhexanoate--CoA-ligase
MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPIQQIKALQIIEDDKANLQHLTQECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSFGQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPYVKGELCVSDDLTYTTGYFASAKIGYHRLFDIKPVNTRYGGRIIFVDDRIDLNHYISFLESTPKQVVYERV
>NZ_CP017115.1|WP_000200943.1|2481009_2481477_-|hypothetical-protein
MTSKDITQISVIAAILTILAALKIPSIIPGLDFQLSAPAALLILAFFGIKKYFLGGLLSSLLLLVFGVFNPINVIISIIFRVIAIAVVYLLKINVLSLVLASVLGSLVSRLLLSIILNLPVWVVLLNAIPGVIFTLIVAIPLYLTLRKRMAVLLR
>NZ_CP017115.1|WP_000783428.1|2479980_2480958_+|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B
MKMNKLVKSSVATSMALLLLSGTANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKATGNINSGFVKPNPNDYDFSKLYWGAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTLGYTFGGDISISNGLSGGLNGNTAFSETINYKQESYRTTLSRNTNYKNVGWGVEAHKIMNNGWGPYGRDSFHPTYGNELFLAGRQSSAYAGQNFIAQHQMPLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMDLYQIRWNGFYWAGANYKNFKTRTFKSTYEIDWENHKVKLLDTKETENNK
>NZ_CP017115.1|WP_000482647.1|2490972_2491080_-|type-I-toxin-antitoxin-system-Fst-family-toxin
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK
>NZ_CP017115.1|WP_000779360.1|2491213_2491600_-|GtrA-family-protein
MKLTQTHAEILKFIIVGGINTLNYYVVYLLLLKLLHIEYMISHITGFLVAFVISYYLNCYFVYRVKPTWRKFISFPITQIVNVSLQTVLLYVFVSWLNLPAEIAPFAGLVITIPITFVLSKWILKDSN
>NZ_CP017115.1|WP_001176871.1|2491857_2493000_+|glycerate-kinase
MQLQKIVIAPDSFKESMTAQQVGNIIKQAFTNVYGNTLHYDIIPMADGGEGTTDALMHATGATKYTVIVNDPLMRPIEACYARADEQQIAIIEMAAASGLDLLEKEERNPLYTSSYGTGELIKDALNHGAKTIILGIGGSATNDGGTGMLSALGVQFTDVNGDLLQMNGANLAHIAQIDITNLDSRLKEVTFKVACDVSNPLLGENGATYIYGPQKGADAKMIPKLDFAMSHYHDKIKMCTGKSVNQIPGSGAAGGMGAALLAFCETTLTKGIDVVFDITDFHQRIKDADLVITGEGRMDYQTIFGKTPVGVALAAKQYHIPVIAICGSLGENYQHVYDFGIDSAYSIISSPSTLEDVLQNSEQNLLNTATDIARILKLQ
>NZ_CP017115.1|WP_000831301.1|2493059_2493719_+|membrane-protein
MKRTDKYRDSYQYDNQNQNHRRQSEDASYRQQYAKGDPEEHPERYYNGRDYRREQILEEENEKSRRSKKWLYIIIAILLIIVAIFVTRALLNNDSDKVSNDPKVSQNYKKQVENQDGQINQQVDNAKENIKNNQKTDDIIKNLQNQIDNLKQQEQNKADSKLTQFYQDQINKLTEANNALKNNASQGKIESMLNDINTKFDSIKSKLESLFKDENGGAN
>NZ_CP017115.1|WP_001192075.1|2493900_2495112_+|multidrug-effflux-MFS-transporter
MQSTKTKTKHFSFLLLITLGVMTAFGPLTIDMYVPSLPKVQGDFGSTTSEIQLTLSFTMIGLALGQFIFGPLSDAFGRKRIAVSILIIFILVSGLSMFVDQLPLFLTLRFIQGLTGGGVIVIAKASAGDKFSGNALAKFLASLMVVNGIITILAPLAGGLALSVATWRSIFTILTIVALIILIGVASQLPKTSKDELKQVNFSSVIKDFGSLLKKPAFIIPMLLQGLTYVMLFSYSSASPFITQKLYNMTPQQFSIMFAVNGVGLIIVSQVVALLVEKLHRHILLIILTIIQVVGVALIILTLTFHLPLWVLLIAFFLNVCPVTSIGPLGFTMAMEERTGGSGNASSLLGLFQFILGGAVAPLVGLKGEFNTSPYMIIIFITAILLVSLQIIYFKMIKKQHVA
>NZ_CP017115.1|WP_000456497.1|2495234_2495708_-|AraC-family-transcriptional-regulator
MEYQLQQLASLTLVGIKETYENGRQAQQHIAGFWQRCYQEGVIADLQLKNNGDLAGILGLCISELDGKMSYMIAVTGDNSADIEKYDVITLASSKYMVFEAQGAVPKAVQQKMEEVHHYIHQYQADTVKSAPFFELYQDGDTTSEKYITEIWMPVKG
>NZ_CP017115.1|WP_001080281.1|2495820_2496477_+|hypothetical-protein
MNRKILPVKPISQLFPIPMVMGCEGVSAAMMLQYNNQHIPATEIMRHWPTHPNNPHKGYVGHHLFIKLGNYHQTIFPEAYVPFLQKYNPNIVDGTGKSLEDLKGIIDQGQPVLIYHTNLGSKPLLRVFRFDNKPAKQVSNIHVTLLIGYDDYYYYYIDPLWSHIRRGLVLPAIIPNRKQIIKIRKEKMEYSFNSPGRKCIYVQPHSYTIENQQQNKHT
>NZ_CP017115.1|WP_000690199.1|2496539_2497346_-|phosphohydrolase
MKIGTIADLHIDRHNKKTSEDYLEALVEIVKYKKLDILLIAGDISNHYQLTHQFITQLTKQLDIPVKFVPGNHDLWEVESMTTQDIWNNYKSMSQCLVGKPFIVNEEWAIIGHTGWYDYSFAAQRFSLEHLQKGKHYGATWQDKERISWGISDQNLSKIAAEQVKKDILEVGNRRVILVTHVVTHPDFIVPMPHRIFDFYNAFIGTSDFNPLYAMFDIPYSIMGHVHFRKSVIDDGRCYLCPCLGYPRQWRSEDIYQEINETIQIIEI
>NZ_CP017115.1|WP_000101538.1|2497631_2499041_+|amino-acid-permease
MARKLHRELNNRHIQLIAIGGAIGTGLFLGSGQTISLTGPSLLFTYMIIGVVLFAFMRALGELLLSNTRFNSFVDIANEYLGPFGGFVIGWTYWLCWIVSSMSDLTAMGQYFAFWYPQVPNWITVLFIVLILISFNLLGARLFGELEFWFSIIKVVTIIAMVIVGLVLIFFSFKTHYGHASFTNLISHGGMFPGGTFGFLMSFQIAVYSFIGIELIGVTAGETKDPEKTLPKAINNVPIRILLFYIGGLLVIMSVIPWNDIDPNSSPFVKLFTLIGVPFAAGVVNFVVLTAAASATNSGIYSNSRILFGLSQQGLGPKVLNKTNSHGVPYLSMLVSSIALLIAALLNYIFPNAIQLFIYVTTLSTVLFLVVWAMIIVAYLMYLKKHPEAHKNSKFKLIGGKPIAYIILAFFFFVFILLFFSDETRAAIYISPFWFIFLFFFYKKYKTNAEKLAYEQRQNDSGHFRYDNQ
>NZ_CP017115.1|WP_001185692.1|2499178_2501257_+|sodium:proton-antiporter
MALLEAFLIFIFAVIISSVINNRFPQIPTAFIQIALGVVIFIIPIQVDFQFNSEVFMFAVIAPLLFVEGTHVSRTKLLEYRKPILLMSMALVFATVVGVGYFIHWIWPALPMPAAFAIAAILCPTDAVAVSAITRGKLLPKGSMTILEGESLLNDAAGIISFKIAVTALVTGTFSLFQAVEQFIISTILGVLIGAIIGFVVVRIRIDLTANKGLKDNNTLTFIQLLTPFVVYFLAEEVHASGIIAVVIAGLIHGLERDRLIRAQTELQMNYHQIWNTFSYALNGFVFVVLGFMIPTVVIDIFQTEPDNFSFLIVITILIAIAIYACRFVWVYFWYKDFYFPKNIQSYLDEEHDSHETPPSRVRYAFIMTMCGIHGTISLSMALTLPFIITKGQAFEYRNDLLFIASFMVLISLILAQIVLPLITPSAEDTTFKGMTYQSAKIFIVQKVIQHFKNESKKDKNDTNYRPVLNQYYGELLFLLNSEPDNQNTKELKRLEDIAKVIETSTLERLIDKGKATYQDINNYRNIVELTETHRTASFVEKFANFFKMLWLRLKAMKHYKALNKESKKQEFENSFKDVQKIMRIVNHNIILRLKEEQNSTNVLEVSLVINHYYDMSRSLKWRAQRRKERQENSNQIIPQAMFHNHKLEALYLQRHLLDELIRKNKINNIVAAQIRENINYNEIVLSLQSKH

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Crispr_ID: NZ_CP017115_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP017115_13

2630693-2630800

Orphan

Consensus_repeat	Method
ATTATTATAAATAATAAGTACACTACGGTTTACAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP017115_13

>merge|NZ_CP017115|13|2630693-2630800|CRISPRCasFinder
ATTATTATAAATAATAAGTACACTACGGTTTACAGTTGGATCTTCGCTCCAACTGCATAAGAGCCACTAATTATTATAAATAATAAGTACACTACGGTTTACAGTTGG

>NZ_CP017115|13|13|2630693-2630800|CRISPRCasFinder
ATTATTATAAATAATAAGTACACTACGGTTTACAGTTGG	ATCTTCGCTCCAACTGCATAAGAGCCACTA
ATTATTATAAATAATAAGTACACTACGGTTTACAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP017115.1\|WP_000432897.1\|2619126_2621121_-\|ferrous-iron-transport-protein-B	unknown	unknown	gnl\|CDD\|223447
NZ_CP017115.1\|WP_001796738.1\|2624833_2625001_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_000686167.1\|2633770_2635279_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224154
NZ_CP017115.1\|WP_000076661.1\|2630872_2631079_+\|copper-chaperone-CopZ	unknown	unknown	gnl\|CDD\|225328
NZ_CP017115.1\|WP_000161355.1\|2631168_2632167_-\|D-lactate-dehydrogenase	unknown	unknown	gnl\|CDD\|181499
NZ_CP017115.1\|WP_000111118.1\|2618943_2619114_-\|FeoB-associated-Cys-rich-membrane-protein	unknown	unknown	gnl\|CDD\|378908
NZ_CP017115.1\|WP_000259692.1\|2625112_2626657_-\|L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|179543
NZ_CP017115.1\|WP_000932073.1\|2621132_2621360_-\|ferrous-iron-transport-protein-A	unknown	unknown	gnl\|CDD\|224830
NZ_CP017115.1\|WP_000725225.1\|2639472_2640240_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP017115.1\|WP_000024129.1\|2628115_2630524_+\|copper-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319783
NZ_CP017115.1\|WP_000136500.1\|2626846_2627446_-\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
NZ_CP017115.1\|WP_001795496.1\|2638809_2639298_-\|glycosyl-4,4'-diaponeurosporenoate-acyltransferase	unknown	unknown	unknown
NZ_CP017115.1\|WP_001051422.1\|2621575_2624065_-\|fatty-acid-efflux-MMPL-transporter-FarE	unknown	unknown	gnl\|CDD\|225272
NZ_CP017115.1\|WP_000665232.1\|2624209_2624758_+\|fatty-acid-efflux-pump-transcriptional-regulator-FarR	unknown	unknown	gnl\|CDD\|224228
NZ_CP017115.1\|WP_000625079.1\|2632189_2633344_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|181219
NZ_CP017115.1\|WP_000178307.1\|2635290_2636154_-\|phytoene/squalene-synthase-family-protein	unknown	unknown	gnl\|CDD\|224478
NZ_CP017115.1\|WP_088607417.1\|2637323_2638817_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224154
NZ_CP017115.1\|WP_001221402.1\|2627684_2627876_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP017115.1\|WP_000871731.1\|2636190_2637318_-\|4,4'-diaponeurosporenoate-glycosyltransferase	unknown	unknown	gnl\|CDD\|132997
NZ_CP017115.1\|WP_000379821.1\|2640600_2642412_-\|O-acetyltransferase-OatA	unknown	unknown	gnl\|CDD\|224748

Protein	Function_ID	Function_description	E-value
NZ_CP017115.1\|WP_000932073.1\|2621132_2621360_-\|ferrous-iron-transport-protein-A	gnl\|CDD\|224830	COG1918, FeoA, Fe2+ transport system protein A [Inorganic ion transport and metabolism].	9.02667e-20
NZ_CP017115.1\|WP_000432897.1\|2619126_2621121_-\|ferrous-iron-transport-protein-B	gnl\|CDD\|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	0
NZ_CP017115.1\|WP_000686167.1\|2633770_2635279_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	1.03717e-133
NZ_CP017115.1\|WP_000076661.1\|2630872_2631079_+\|copper-chaperone-CopZ	gnl\|CDD\|225328	COG2608, CopZ, Copper chaperone [Inorganic ion transport and metabolism].	3.85103e-21
NZ_CP017115.1\|WP_000725225.1\|2639472_2640240_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.53845e-31
NZ_CP017115.1\|WP_000111118.1\|2618943_2619114_-\|FeoB-associated-Cys-rich-membrane-protein	gnl\|CDD\|378908	pfam12669, P12, Virus attachment protein p12 family. This family of proteins are related to Virus attachment protein p12 from the African swine fever virus. The family appears to contain an N-terminal signal peptide followed by a short cysteine rich region. The cysteine rich region is extremely variable and it is possible that only the N-terminal region is homologous.	0.00119197
NZ_CP017115.1\|WP_000259692.1\|2625112_2626657_-\|L-glutamate-gamma-semialdehyde-dehydrogenase	gnl\|CDD\|179543	PRK03137, PRK03137, 1-pyrroline-5-carboxylate dehydrogenase; Provisional.	0
NZ_CP017115.1\|WP_000161355.1\|2631168_2632167_-\|D-lactate-dehydrogenase	gnl\|CDD\|181499	PRK08605, PRK08605, D-lactate dehydrogenase; Validated.	0
NZ_CP017115.1\|WP_000024129.1\|2628115_2630524_+\|copper-translocating-P-type-ATPase	gnl\|CDD\|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP017115.1\|WP_000136500.1\|2626846_2627446_-\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	5.94515e-91
NZ_CP017115.1\|WP_001051422.1\|2621575_2624065_-\|fatty-acid-efflux-MMPL-transporter-FarE	gnl\|CDD\|225272	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only].	1.58078e-171
NZ_CP017115.1\|WP_000665232.1\|2624209_2624758_+\|fatty-acid-efflux-pump-transcriptional-regulator-FarR	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	8.81924e-09
NZ_CP017115.1\|WP_000178307.1\|2635290_2636154_-\|phytoene/squalene-synthase-family-protein	gnl\|CDD\|224478	COG1562, ERG9, Phytoene/squalene synthetase [Lipid metabolism].	2.37403e-100
NZ_CP017115.1\|WP_088607417.1\|2637323_2638817_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	1.37617e-132
NZ_CP017115.1\|WP_000625079.1\|2632189_2633344_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|181219	PRK08068, PRK08068, transaminase; Reviewed.	2.7078e-143
NZ_CP017115.1\|WP_000871731.1\|2636190_2637318_-\|4,4'-diaponeurosporenoate-glycosyltransferase	gnl\|CDD\|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	9.85714e-23
NZ_CP017115.1\|WP_000379821.1\|2640600_2642412_-\|O-acetyltransferase-OatA	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	6.58134e-84

>NZ_CP017115.1|WP_000024129.1|2628115_2630524_+|copper-translocating-P-type-ATPase
MANTKKTTLDITGMTCAACSNRIEKKLNKLDDVNAQVNLTTEKATVEYNPDQHDVQEFINTIQHLGYGVAVETVELDITGMTCAACSSRIEKVLNKMDGVQNATVNLTTEQAKVDYYPEETDADKLVTRIQKLGYDASIKDNNKDQTSRKAEALQHKLIKLIISAVLSLPLLMLMFVHLFNMHIPALFTNPWFQFILATPVQFIIGWQFYVGAYKNLRNGGANMDVLVAVGTSAAYFYSIYEMVRWLNGSTTQPHLYFETSAVLITLILFGKYLEARAKSQTTNALGELLSLQAKEARILKDGNEVMIPLNEVHVGDTLIVKPGEKIPVDGKIIKGMTAIDESMLTGESIPVEKNVDDTVIGSTMNKNGTITMTATKVGGDTALANIIKVVEEAQSSKAPIQRLADIISGYFVPIVVGIALLTFIVWITLVTPGTFEPALVASISVLVIACPCALGLATPTSIMVGTGRAAENGILFKGGEFVERTHQIDTIVLDKTGTITNGRPVVTDYHGDNQTLQLLATAEKDSEHPLAEAIVNYAKEKQLTLTETTTFKAVPGHGIEATIDHHHILVGNRKLMADNDISLPKHISDDLTYYERDGKTAMLIAVNYSLTGIIAVADTVKDHAKDAIKQLHDMGIEVAMLTGDNKNTAQAIAKQVGIDTVIADILPEEKAAQIAKLQQQGKKVAMVGDGVNDAPALVKADIGIAIGTGTEVAIEAADITILGGDLMLIPKAIYASKATIRNIRQNLFWAFGYNIAGIPIAALGLLAPWVAGAAMALSSVSVVTNALRLKKMRLEPRRKDA
>NZ_CP017115.1|WP_001221402.1|2627684_2627876_+|hypothetical-protein
MRILITGTVAILIILGLVKTIQDHEMTNDTSRQLSDNKDDDKVIHLNNFKNLHAKEFNPSDFF
>NZ_CP017115.1|WP_000136500.1|2626846_2627446_-|sugar-O-acetyltransferase
MTEKEKMLAEKWYDANFDQYLINERARAKDICFELNHTRPSATNKRKELIDQLFQTTTDNVSISIPFDTDYGWNVKLGKNVYVNTNCYFMDGGQITIGDNVFIGPNCGFYTATHPLNFHHRNEGFEKAGPIHIGSNTWFGGHVAVLPGVTIGEGSVIGAGSVVTKDIPPHSLAVGNPCKVVRKIDNDLPSETLNDETIK
>NZ_CP017115.1|WP_000259692.1|2625112_2626657_-|L-glutamate-gamma-semialdehyde-dehydrogenase
MVVEFKNEPGYDFSVQENVDMFKKALKDVEKELGQDIPLVINGEKIFKDDKIKSINPADTSQVIANASKATKQDVEDAFKAANEAYKSWKTWSANDRAELMLRVSAIIRRRKAEIAAIMVYEAGKPWDEAVGDAAEGIDFIEYYARSMMDLAQGKPVLDREGEHNKYFYKSIGTGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTPYIAYKLMEILEEAGLPKGVVNFVPGDPKEIGDYLVDHKDTHFVTFTGSRATGTRIYERSAVVQEGQNFLKRVIAEMGGKDAIVVDENIDTDMAAEAIVTSAFGFSGQKCSACSRAIVHKDVYDEVLEKSIKLTKELTLGNTVDNTYMGPVINKKQFDKIKNYIEIGKEEGKLEQGGGTDDSKGYFVEPTIISGLKSKDRIMQEEIFGPVVGFVKVNDFDEAIEVANDTDYGLTGAVITNNREHWIKAVNEFDVGNLYLNRGCTSAVVGYHPFGGFKMSGTDAKTGSPDYLLHFLEQKVVSEMF
>NZ_CP017115.1|WP_001796738.1|2624833_2625001_-|hypothetical-protein
MRYVISIIMGIVLAIWSFKQLSQSHLDSGFIFFFIVYVLCISYFNSDKHDKNKKR
>NZ_CP017115.1|WP_000665232.1|2624209_2624758_+|fatty-acid-efflux-pump-transcriptional-regulator-FarR
MKETDLRVIKTKKALSSSLLQLLEQQLFQTITVNQICDNALVHRTTFYKHFYDKYDLLEYLFNQLTKDYFARDISDRLNHPFQTISDTINNKEDLRDIAEFQEEDAEFNKVLKNVCIKIMHNDIKNNRDRIDIDSDIPDNLIFYIYDSLIEGFMHWIKDEKIDWPGEEIDKIFHKVINIKIK
>NZ_CP017115.1|WP_001051422.1|2621575_2624065_-|fatty-acid-efflux-MMPL-transporter-FarE
MAKFLYKMGTFIAKHKWSAVIAWIVIVAAILIPLATNAPKFDNDIKMTGLESLDTNKKIEKHFNQDSEKAQIRVVFKTTKDDGIVQPNITKDIKKTLDDIKKDDKHIDKISDPYENKQISKDKTTAFADITYDVSQTSLKDGSRDNVKSHLKDLRDNHNVQTELTGTGMTSTEVGGNSELVGIIVAFVVLLITFGSVIAAGLPIISALIGLASGVGIISLLTYAFDIPNVTLTLAVMIGLAVGIDYALFILFRYRQVMKTETDYIKGIGLAIGTAGSAVIFAGVTVVIAVCGLSLVGIDFLAVMGFASAISVIFAVFSALTLLPALISIFHKRIKVNKLQSNFKKDIDTPWSKFITGNALAAVLLGLIILVAAAIPVSHMRLGIPDDGVKPADSTQKKAYDIISDKFGEGFNGQIPMLINVKDKKDDPQGLQQDLQSVYKDIKDKKNVDIVTPPQMSKDNDYALMVVIPKKGPNAESTNDLVHDLRDYHKDAQDKYGFKTEISGQSVINIDMSKKLNEAIPLFATVIVVLAFFLLMIVFRSILIPLKAVLGFVLSLMATLGFTTLVMQDGFMKGLFGIETTGPMLAFLPVITIGILFGLAMDYEVFLMSRIHEEYSKTGDNDYSIKVGLKESGPVIVAAALIMFSVFFAFVFQEDVMIKSMGMALAFGVLFDAFVVRMMLIPALTKLFGKGSWYLPAWLNRIIPRVDIEGHALEKYKTVESQESEAKDSKETYDTTFKIYPQGATNVSKHQDVHGQDDVRSIVLDDKTMALYQEVKQQSASSFFLYDALIDYQNKHQLNSKQQVTNIEQLNKNIEKLNQLLEKNLRNKS
>NZ_CP017115.1|WP_000932073.1|2621132_2621360_-|ferrous-iron-transport-protein-A
MLNIKNGEMNKAYKIKRMDIANENMLYRLSAFGLTDDAIITIKQKCLFKGPCIIEVNGQQLSIRHCDACSIALEE
>NZ_CP017115.1|WP_000432897.1|2619126_2621121_-|ferrous-iron-transport-protein-B
MENYCILGNPNVGKTSLFNALTGSYEYIGNWSGVTVEKKVGKLKENVGQLIDLPGTYDLSPISKDETVVTDYLLNDSFSGIINIVDASQLKRNMQLTVQLLELNQPIYIGLNMIDVATKRGIKIDYHKLMKKLKTPIFPVVARTGKGTKHLLGEIKHLGEGYQPHFKINYGEKIEETIKNMCQIIMTETSHDKYQARFIAIQFLLNNMQIANELNSEVVNKLSSLRDQVDKQVEAVSVRREMERIRNHYIETLLQDVVTYPDEDKQYFSSRIDKILTHKYIGMPIFLAIMWLIFQTTFTWIGTPLSDQLDAFIGGTFTDSVKTIMNYLGVIPFLQDLITDGIIAGVGSVLVFVPQIVVLFFFISLLEDSGYMARIAVLMDRIMESFGLSGKSFIPMIIGFGCNVPSIMAARSIENEKERLTTILIAPFMSCSARLPVYALFVGIFFKENQSLVVLSLYVLGIIMAFLVSTVLTKTILKNDNAIFIVELPTYRVPSIKTLWRSTWEKAKGFVRKAGTFIFGGSVVIWLLSYVGPHGINVNINQSFLHMVGSFFGMLVQPLGFGTWQAGATLVPGFLAKEVIVSSMAIIYSSGDAGLVNVIQNQFTPLSAYAFMIFILLYIPCVSTVAAIRKETYSWKWTALAVVYPLVTAYVLTFIFYQIGHLFV
>NZ_CP017115.1|WP_000111118.1|2618943_2619114_-|FeoB-associated-Cys-rich-membrane-protein
MSVIINILIFLAIFGYALYTLVKFFKRSKQGKCGTCDINRDCCGTEQHTANHFPGK
>NZ_CP017115.1|WP_000076661.1|2630872_2631079_+|copper-chaperone-CopZ
MSQEILNVEGMSCGHCKSAVESALNNIDGVTSADVNLENGQVSVQYDDSKVAVSQMKDAIEDQGYDVV
>NZ_CP017115.1|WP_000161355.1|2631168_2632167_-|D-lactate-dehydrogenase
MTKIKIMSVRDEDMPYIKAWAEKHHVEVDITKEALTDDNVEGVAGYDGLSLSQQIPLSEHVYKRLNELDIKQIAQRSAGFDTYDLELANKYNLIVSNVPSYSPNSIAEFAVNQAINVVRHFNQIQTKVREHDFRWEPTILSKSIKDLKVAVIGTGRIGRVVADIFANGYQSDVVAYDPFPNAKIATYVDYKDTIEEAVEGADIVTLHVPATKYNHYLFNAELFKHFKKGAVFVNCARGSLVDTKALLDALDNGVIKGAALDTYEFERKLFPSDQRGKTLNDPLLESLIDREDVILTPHIAFYTEAAVKNLIVDALDATLDVLQTGDTRLRVN
>NZ_CP017115.1|WP_000625079.1|2632189_2633344_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MISNKLANIPDSYFGKTMGRKIEHGPLPLINMAVGIPDGPTPQGIIDHFQQALTIPENQKYGAFHGKEAFKQAIVDFYQRQYNVTLDKEDEVCILYGTKNGLVAVPTCVINPGDYVLLPDPGYTDYLAGVLLADGKPVPLNLEPPHYLPDWSTVDSQIIDKTKLIYLTYPNNPTGSTATKEVFDEAIAKFKDTDTKIVHDFAYGAFGFDAKNPSILASENGKDVAIEIYSLSKGYNMSGFRVGFAVGNKDMIQALKKYQTHTNAGMFGALQDAAIYALNHYDDFLEEQSNVFKTRRDRFEAMLAKADLPFVHAKGGIYVWLETPPGYDSEQFEQFLVQEKSILVAPGKPFGENGNRYVRISLALDDQKLDEAAIRLTELAYLYE
>NZ_CP017115.1|WP_000686167.1|2633770_2635279_-|NAD(P)/FAD-dependent-oxidoreductase
MKIAVIGAGVTGLAAAARIASQGHEVTIFEKNNNVGGRMNQLKKDGFTFDMGPTIVMMPDVYKDVFTACGKNYEDYIELRQLRYIYDVYFDHDDRITVPTDLAELQQMLESIEPGSTHGFMSFLTDVYKKYEIARRYFLERTYRKPSDFYNMTSLVQGAKLKTLNHADQLIEHYIDNEKIQKLLAFQTLYIGIDPKRGPSLYSIIPMIEMMFGVHFIKGGMYGMAQGLAQLNKDLGVNIELNAEIEQIIIDPKFKRADAIKVNGDIRKFDKILCTADFPSVAESLMPDFAPIKKYPPHKIADLDYSCSAFLMYIGIDIDVTDQVRLHNVIFSDDFRGNIEEIFEGRLSYDPSIYVYVPAVADKSLAPEGKTGIYVLMPTPELKTGSGIDWSDEALTQQIKEIIYRKLATIEVFEDIKSHIVSETIFTPNDFEQTYHAKFGSAFGLMPTLAQSNYYRPQNVSRDYKDLYFAGASTHPGAGVPIVLTSAKITVDEMIKDIEQGV
>NZ_CP017115.1|WP_000178307.1|2635290_2636154_-|phytoene/squalene-synthase-family-protein
MTMMDMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVCRKIDDSIDVYGDIQFLNQIKEDIQSIEKYPYEHHHFQSDRRIMMALQHVAQHKNIAFQSFYNLIDTVYKDQHFTMFETDAELFGYCYGVAGTVGEVLTPILSDHETHQTYDVARRLGESLQLINILRDVGEDFDNERIYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAIAEKDFQDVMDQIKVFSIEAQPIIELAARIYIEILDEVRQANYTLHERVFVDKRKKAKLFHEINSKYHRI
>NZ_CP017115.1|WP_000871731.1|2636190_2637318_-|4,4'-diaponeurosporenoate-glycosyltransferase
MKWLSRILTVIVTMSMACGALIFNRRHQLKAKTLNFNHKALTIIIPARNEEKRIGHLLHSIIQQQVPVDVIVMNDGSTDETARVARSYGATVVDVVDDTDGKWYGKSHACYQGVTHACTNRIAFVDADVTFLRKDAVETLINQYQLQGEKGLLSVQPYHITKRFYEGFSAIFNLMTVVGMNVFSTLDDGRTNQHAFGPVTLTNKEDYYATGGHKSANRHIIEGFALGSAYTSQSLPVTVYEGFPFVAFRMYQEGFQSLQEGWTKHLSTGAGGTKPKIMTAIVLWLFGSIASILGLCLSLKYRQMSVRKMVALYLSYTTQFIYLHRRVGQFSNLLMVCHPLLFMFFTKIFIQSWKQTHRYGVVEWKGRQYSISKEQ
>NZ_CP017115.1|WP_088607417.1|2637323_2638817_-|NAD(P)/FAD-dependent-oxidoreductase
MTKHIIVIGGGLGGISAAIRMAQSGYSVSLYEQNNHIGGKVNRHESDGFGFDLGPSILTMPYIFEKLFEYSKKQMSDYVTIKRLPHQWRSFFPDGTTIDLYEGIKETGQHNAILSKQDIEELQNYLNYTRRIDRITERGYFNYGLDTLSQIIKFHGPLNALINYDYVHTMQQAIDKRISNPYLRQMLGYFIKYVGSSSYDAPAVLSMLFHMQQEQGLWYVEGGIHHLANALEKLAREEGVTIHTGARVDNIKTYQRRVTGVRLDTGEFVKADYIISNMEVIPTYKYLIHLDTQRLNKLEREFEPASSGYVMHLGVACQYPQLAHHNFFFTENAYLNYQQVFHEKVLPDDPTIYLVNTNKTDHTQAPVGYENIKVLPHIPYIQDQPFTTEDYAKFRDKILDKLEKMGLTDLRKHIIYEDVWTPEDIEKNYRSNRGAIYGVVADKKKNKGFKFPKESQYFENLYFVGGSVNPGGGIPMVTLSGQQVADKINAREAKNRK
>NZ_CP017115.1|WP_001795496.1|2638809_2639298_-|glycosyl-4,4'-diaponeurosporenoate-acyltransferase
MKKYIKTAFFCSMYWLIVQLNIANLGTRIPDKYFRQKYIIFKSFNFEKHGKFWNKWFYVRKWKHKILDGHQLNQNIYDQRHLMTINTDEIEKMIIETKRAELIHWISILPVIIFNKGPRLVKYINIFYAMIANVPIIIVQRYNRPRLTQLLRILKRRGERHD
>NZ_CP017115.1|WP_000725225.1|2639472_2640240_-|CHAP-domain-containing-protein
MKKIVTATIATAGLATIAFAGHDAQAAEQNNNGYNSNDAQSYSYTYTIDAQGNYHYTWTGNWNPSQLTQNNTYYYNNYNTYSYNNASYNNYYNHSYQYNNYTNNSQTATNNYYTGGSGASYSTTSNNVHVTTTAAPSSNGRSISNGYASGSNLYTSGQCTYYVFDRVGGKIGSTWGNASNWANAAASSGYTVNNTPKVGAIMQTTQGYYGHVAYVEGVNSNGSVRVSEMNYGHGAGVVTSRTISANQAGSYNFIH
>NZ_CP017115.1|WP_000379821.1|2640600_2642412_-|O-acetyltransferase-OatA
MDTKDFKRLEKMYSPRYLPGLDGLRAFAVIGIIIYHLNAQWLSGGFLGVDTFFVISGYLITSLLISEYYRTQKIDLLEFWKRRLKRLIPAVLFLICVVLTFTLIFKPELIIQMKRDAIAAIFYVSNWWYISQNVDYFNQFAIEPLKHLWSLAIEEQFYLLFPLVITFLLHRFKPRNIIQTLFIVSLISLGLMIVIHFITGDNSRVYFGTDTRLQTLLLGCILAFIWPPFALKKDISKKIVVSLDIIGISGFAVLMTLFFIVGDQDQWIYNGGFYIISFATLFIIAIAVHPSSLFAKFLSMKPLLIIGKRSYSLYLWHYPIIVFVNSYYVQGQIPVYVYIIEILLTALMAEISYRFIETPIRKKGFKAFAFLPKKKGQFARTVLVILLLVPSIVVLSGQFDALGKQHEAEKKEKKTEFKTTKKKVVKKDKQEDKQTANSKEDIKKSSPLLIGDSVMVDIGNVFTKKIPNAQIDGKVGRQLVDATPIVKSQYKDYAKKGQKVVVELGTNGAFTKDQLNELLDSFGKADIYLVSIRVPRDYEGRINKLIYEAAEKRSNVHLVDWYKASAGHPEYFAYDGIHLEYAGSKALTDLIVKTMETHATNKK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP017115_1	1.1\|811834\|29\|NZ_CP017115\|CRISPRCasFinder	811834-811862	29	NZ_CP017115.1	2763178-2763206	0	1.0
NZ_CP017115_5	5.1\|1209079\|26\|NZ_CP017115\|CRISPRCasFinder	1209079-1209104	26	NZ_CP017115.1	286449-286474	0	1.0
NZ_CP017115_5	5.1\|1209079\|26\|NZ_CP017115\|CRISPRCasFinder	1209079-1209104	26	NZ_CP017115.1	2763090-2763115	0	1.0
NZ_CP017115_1	1.1\|811834\|29\|NZ_CP017115\|CRISPRCasFinder	811834-811862	29	NZ_CP017115.1	364057-364085	1	0.966
NZ_CP017115_1	1.1\|811834\|29\|NZ_CP017115\|CRISPRCasFinder	811834-811862	29	NZ_CP017115.1	1462370-1462398	1	0.966
NZ_CP017115_1	1.1\|811834\|29\|NZ_CP017115\|CRISPRCasFinder	811834-811862	29	NZ_CP017115.1	1822334-1822362	1	0.966
NZ_CP017115_2	2.1\|859294\|34\|NZ_CP017115\|CRISPRCasFinder	859294-859327	34	NZ_CP017115.1	1333492-1333525	1	0.971
NZ_CP017115_2	2.1\|859294\|34\|NZ_CP017115\|CRISPRCasFinder	859294-859327	34	NZ_CP017115.1	1424597-1424630	1	0.971
NZ_CP017115_5	5.1\|1209079\|26\|NZ_CP017115\|CRISPRCasFinder	1209079-1209104	26	NZ_CP017115.1	859628-859653	1	0.962
NZ_CP017115_5	5.1\|1209079\|26\|NZ_CP017115\|CRISPRCasFinder	1209079-1209104	26	NZ_CP017115.1	2763146-2763171	1	0.962
NZ_CP017115_1	1.1\|811834\|29\|NZ_CP017115\|CRISPRCasFinder	811834-811862	29	NZ_CP017115.1	161967-161995	2	0.931
NZ_CP017115_1	1.1\|811834\|29\|NZ_CP017115\|CRISPRCasFinder	811834-811862	29	NZ_CP017115.1	162025-162053	2	0.931
NZ_CP017115_1	1.1\|811834\|29\|NZ_CP017115\|CRISPRCasFinder	811834-811862	29	NZ_CP017115.1	817268-817296	2	0.931
NZ_CP017115_1	1.1\|811834\|29\|NZ_CP017115\|CRISPRCasFinder	811834-811862	29	NZ_CP017115.1	859336-859364	2	0.931
NZ_CP017115_1	1.1\|811834\|29\|NZ_CP017115\|CRISPRCasFinder	811834-811862	29	NZ_CP017115.1	908080-908108	2	0.931
NZ_CP017115_1	1.1\|811834\|29\|NZ_CP017115\|CRISPRCasFinder	811834-811862	29	NZ_CP017115.1	1126164-1126192	2	0.931
NZ_CP017115_1	1.1\|811834\|29\|NZ_CP017115\|CRISPRCasFinder	811834-811862	29	NZ_CP017115.1	1643484-1643512	2	0.931
NZ_CP017115_5	5.1\|1209079\|26\|NZ_CP017115\|CRISPRCasFinder	1209079-1209104	26	NZ_CP017115.1	780233-780258	2	0.923
NZ_CP017115_5	5.1\|1209079\|26\|NZ_CP017115\|CRISPRCasFinder	1209079-1209104	26	NZ_CP017115.1	780289-780314	2	0.923
NZ_CP017115_5	5.1\|1209079\|26\|NZ_CP017115\|CRISPRCasFinder	1209079-1209104	26	NZ_CP017115.1	780345-780370	2	0.923
NZ_CP017115_5	5.1\|1209079\|26\|NZ_CP017115\|CRISPRCasFinder	1209079-1209104	26	NZ_CP017115.1	824441-824466	2	0.923
NZ_CP017115_11	11.1\|2322375\|26\|NZ_CP017115\|CRISPRCasFinder	2322375-2322400	26	NZ_CP017115.1	1126088-1126113	2	0.923

1. spacer 1.1|811834|29|NZ_CP017115|CRISPRCasFinder matches to position: 2763178-2763206, mismatch: 0, identity: 1.0

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtttgtagaatttcttttcgaaa	Protospacer
*****************************

2. spacer 5.1|1209079|26|NZ_CP017115|CRISPRCasFinder matches to position: 286449-286474, mismatch: 0, identity: 1.0

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacatagaagctggcgg	Protospacer
**************************

3. spacer 5.1|1209079|26|NZ_CP017115|CRISPRCasFinder matches to position: 2763090-2763115, mismatch: 0, identity: 1.0

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacatagaagctggcgg	Protospacer
**************************

4. spacer 1.1|811834|29|NZ_CP017115|CRISPRCasFinder matches to position: 364057-364085, mismatch: 1, identity: 0.966

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcttgtagaatttcttttcgaaa	Protospacer
*******.*********************

5. spacer 1.1|811834|29|NZ_CP017115|CRISPRCasFinder matches to position: 1462370-1462398, mismatch: 1, identity: 0.966

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaa	Protospacer
********.********************

6. spacer 1.1|811834|29|NZ_CP017115|CRISPRCasFinder matches to position: 1822334-1822362, mismatch: 1, identity: 0.966

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaa	Protospacer
********.********************

7. spacer 2.1|859294|34|NZ_CP017115|CRISPRCasFinder matches to position: 1333492-1333525, mismatch: 1, identity: 0.971

attgagaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
****.*****************************

8. spacer 2.1|859294|34|NZ_CP017115|CRISPRCasFinder matches to position: 1424597-1424630, mismatch: 1, identity: 0.971

attgagaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
****.*****************************

9. spacer 5.1|1209079|26|NZ_CP017115|CRISPRCasFinder matches to position: 859628-859653, mismatch: 1, identity: 0.962

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacacagaagctggcgg	Protospacer
*************.************

10. spacer 5.1|1209079|26|NZ_CP017115|CRISPRCasFinder matches to position: 2763146-2763171, mismatch: 1, identity: 0.962

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacaaagaagctggcgg	Protospacer
************* ************

11. spacer 1.1|811834|29|NZ_CP017115|CRISPRCasFinder matches to position: 161967-161995, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

12. spacer 1.1|811834|29|NZ_CP017115|CRISPRCasFinder matches to position: 162025-162053, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

13. spacer 1.1|811834|29|NZ_CP017115|CRISPRCasFinder matches to position: 817268-817296, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaaattcttttcgaaa	Protospacer
********.******* ************

14. spacer 1.1|811834|29|NZ_CP017115|CRISPRCasFinder matches to position: 859336-859364, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

15. spacer 1.1|811834|29|NZ_CP017115|CRISPRCasFinder matches to position: 908080-908108, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

16. spacer 1.1|811834|29|NZ_CP017115|CRISPRCasFinder matches to position: 1126164-1126192, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaatttctttttgaaa	Protospacer
********.***************.****

17. spacer 1.1|811834|29|NZ_CP017115|CRISPRCasFinder matches to position: 1643484-1643512, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

18. spacer 5.1|1209079|26|NZ_CP017115|CRISPRCasFinder matches to position: 780233-780258, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacacagaagcaggcgg	Protospacer
*************.****** *****

19. spacer 5.1|1209079|26|NZ_CP017115|CRISPRCasFinder matches to position: 780289-780314, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacatagaagcagacgg	Protospacer
******************** *.***

20. spacer 5.1|1209079|26|NZ_CP017115|CRISPRCasFinder matches to position: 780345-780370, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacataaaagcaggcgg	Protospacer
***************.**** *****

21. spacer 5.1|1209079|26|NZ_CP017115|CRISPRCasFinder matches to position: 824441-824466, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacacagaagctgacgg	Protospacer
*************.********.***

22. spacer 11.1|2322375|26|NZ_CP017115|CRISPRCasFinder matches to position: 1126088-1126113, mismatch: 2, identity: 0.923

tcgtcaccttctatgttggggccccg	CRISPR spacer
tcgtcagcttctgtgttggggccccg	Protospacer
****** *****.*************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP017115_7	7.1\|1763673\|27\|NZ_CP017115\|CRISPRCasFinder	1763673-1763699	27	KM359505	Prochlorococcus phage P-TIM68, complete genome	102710-102736	5	0.815
NZ_CP017115_1	1.1\|811834\|29\|NZ_CP017115\|CRISPRCasFinder	811834-811862	29	MN693281	Marine virus AFVG_25M371, complete genome	6448-6476	7	0.759
NZ_CP017115_10	10.1\|2223186\|33\|NZ_CP017115\|CRISPRCasFinder	2223186-2223218	33	JN882286	Cronobacter phage vB_CsaP_GAP52, complete genome	23035-23067	7	0.788
NZ_CP017115_10	10.1\|2223186\|33\|NZ_CP017115\|CRISPRCasFinder	2223186-2223218	33	CP030544	Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence	7568-7600	7	0.788
NZ_CP017115_6	6.1\|1677803\|32\|NZ_CP017115\|CRISPRCasFinder	1677803-1677834	32	MT889383	Mycobacterium phage MiniLon, complete genome	11248-11279	9	0.719
NZ_CP017115_6	6.1\|1677803\|32\|NZ_CP017115\|CRISPRCasFinder	1677803-1677834	32	KT281791	Mycobacterium phage Lolly9, complete genome	11248-11279	9	0.719

1. spacer 7.1|1763673|27|NZ_CP017115|CRISPRCasFinder matches to KM359505 (Prochlorococcus phage P-TIM68, complete genome) position: , mismatch: 5, identity: 0.815

gaatttcgaaaagaaattctacagacc	CRISPR spacer
ctatttccaaaagaaattatacagatc	Protospacer
  ***** ********** ******.*

2. spacer 1.1|811834|29|NZ_CP017115|CRISPRCasFinder matches to MN693281 (Marine virus AFVG_25M371, complete genome) position: , mismatch: 7, identity: 0.759

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtttgtaggatttcttctaagtg	Protospacer
**************.*******.* .. .

3. spacer 10.1|2223186|33|NZ_CP017115|CRISPRCasFinder matches to JN882286 (Cronobacter phage vB_CsaP_GAP52, complete genome) position: , mismatch: 7, identity: 0.788

ttgcatatctttagctttattgtttgcaactga	CRISPR spacer
ttgcatatctttagctttatagcttttatatgc	Protospacer
******************** *.** .*  **

4. spacer 10.1|2223186|33|NZ_CP017115|CRISPRCasFinder matches to CP030544 (Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.788

ttgcatatctttagctttattgtttgcaactga	CRISPR spacer
ttgaataactttagctttattgttataaacagt	Protospacer
*** *** ****************   *** *

5. spacer 6.1|1677803|32|NZ_CP017115|CRISPRCasFinder matches to MT889383 (Mycobacterium phage MiniLon, complete genome) position: , mismatch: 9, identity: 0.719

gcacattattgaaatctgacttttggtcagct	CRISPR spacer
accccttcttgaaatctgactttaggtcctga	Protospacer
.* * ** *************** ****

6. spacer 6.1|1677803|32|NZ_CP017115|CRISPRCasFinder matches to KT281791 (Mycobacterium phage Lolly9, complete genome) position: , mismatch: 9, identity: 0.719

gcacattattgaaatctgacttttggtcagct	CRISPR spacer
accccttcttgaaatctgactttaggtcctga	Protospacer
.* * ** *************** ****

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

748923 : 756744

Hokovirus(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000244415.1\|748923_749979_-	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
WP_000149344.1\|749978_750665_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037807.1\|750639_751113_-	DoxX family protein	NA	NA	NA	NA
WP_001093562.1\|751455_751896_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_000604990.1\|752175_752760_-	hypothetical protein	NA	NA	NA	NA
WP_001062972.1\|752858_753572_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000941336.1\|753575_753995_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_000446724.1\|753996_754665_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000604515.1\|755015_755609_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.2e-38	43.5
WP_001217797.1\|755592_756744_+	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	2.1e-23	36.1

DBSCAN-SWA_2

768716 : 783447

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663032.1\|768716_769775_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	1.8e-21	26.7
WP_000197271.1\|770069_770612_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000429008.1\|771292_772210_-	lipid kinase	A0A1V0SBJ0	Catovirus	2.8e-07	22.4
WP_031760357.1\|772299_772401_+	hypothetical protein	NA	NA	NA	NA
WP_000193751.1\|772478_773984_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_000930014.1\|774324_774825_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_001068497.1\|774844_775711_-	DMT family transporter	NA	NA	NA	NA
WP_000692521.1\|776511_776910_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_000855505.1\|776872_778978_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000562498.1\|779095_780067_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000499195.1\|780580_780736_+	hypothetical protein	NA	NA	NA	NA
WP_000876318.1\|780774_781746_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_001245573.1\|781732_782689_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_000616840.1\|782685_783447_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	6.5e-18	31.6

DBSCAN-SWA_3

1026891 : 1035364

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000861572.1\|1026891_1027374_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7
WP_000009495.1\|1027360_1028485_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000174053.1\|1028488_1029193_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
WP_000848350.1\|1029192_1029456_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666801.1\|1029457_1030129_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_000032727.1\|1030121_1032311_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.0e-140	39.7
WP_000483713.1\|1032289_1033774_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-45	31.7
WP_000030823.1\|1033766_1034795_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.3e-61	41.4
WP_000238663.1\|1034797_1035364_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.0e-28	40.1

DBSCAN-SWA_4

1472062 : 1558570

102

Staphylococcus_phage(74.36%)

tail,capsid,holin,integrase,tRNA,transposase,terminase,plate,head,protease,portal

attL 1511821:1511838|attR 1557087:1557104

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000858784.1\|1472062_1473355_-\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	2.5e-54	30.0
WP_000525081.1\|1473676_1476370_-	ATP-dependent helicase DinG	A0A1X9I5C8	Streptococcus_phage	8.2e-47	34.4
WP_000049923.1\|1476393_1477365_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_000361543.1\|1477351_1478554_-\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	3.2e-35	42.5
WP_000690035.1\|1478558_1479701_-	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA	NA	NA	NA	NA
WP_000839926.1\|1479942_1480260_-	nucleotide pyrophosphohydrolase	NA	NA	NA	NA
WP_031774998.1\|1480595_1481276_-	zinc metallopeptidase	NA	NA	NA	NA
WP_000154680.1\|1481347_1481935_-	DUF1405 domain-containing protein	NA	NA	NA	NA
WP_088607377.1\|1481924_1482500_-	IDEAL domain-containing protein	G3MAV7	Bacillus_virus	1.6e-08	27.2
WP_000389510.1\|1482513_1483758_-	hypothetical protein	NA	NA	NA	NA
WP_000245895.1\|1483764_1485063_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_000776341.1\|1485072_1486137_-	3-dehydroquinate synthase	NA	NA	NA	NA
WP_001269923.1\|1486162_1487329_-	chorismate synthase	A0A291AU41	Pandoravirus	2.0e-34	32.1
WP_000195429.1\|1487729_1488902_-\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_000789522.1\|1489047_1489248_-	hypothetical protein	NA	NA	NA	NA
WP_000442479.1\|1489457_1489907_-	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	8.3e-29	44.5
WP_072472612.1\|1489998_1490943_-	heptaprenyl diphosphate synthase	A0A1V0SE37	Indivirus	1.3e-10	24.4
WP_000774677.1\|1490959_1491685_-	demethylmenaquinone methyltransferase	NA	NA	NA	NA
WP_000450555.1\|1491687_1492260_-	heptaprenyl pyrophosphate synthase subunit A	NA	NA	NA	NA
WP_001043863.1\|1492690_1492963_-	DNA-binding protein HU	A7KV42	Bacillus_phage	4.2e-28	73.3
WP_000161738.1\|1493133_1494132_-	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_000165530.1\|1494148_1495459_-	ribosome biogenesis GTPase Der	NA	NA	NA	NA
WP_000133954.1\|1495680_1496856_-	30S ribosomal protein S1	NA	NA	NA	NA
WP_000644391.1\|1497553_1498213_-	(d)CMP kinase	NA	NA	NA	NA
WP_000681769.1\|1498289_1499258_+	asparaginase	NA	NA	NA	NA
WP_001174260.1\|1499372_1500359_-	YpdA family putative bacillithiol disulfide reductase	NA	NA	NA	NA
WP_031867547.1\|1500519_1500636_-	hypothetical protein	NA	NA	NA	NA
WP_001837323.1\|1500760_1502221_-	elastin-binding protein EbpS	NA	NA	NA	NA
WP_000902120.1\|1502373_1503753_-	ATP-dependent DNA helicase RecQ	L7RCS0	Acanthamoeba_polyphaga_moumouvirus	2.9e-56	33.6
WP_001163801.1\|1503742_1504696_-	hypothetical protein	NA	NA	NA	NA
WP_001151997.1\|1504803_1505052_+	ferredoxin	A0A127AYY7	Bacillus_phage	8.3e-15	48.0
WP_001186912.1\|1505157_1505703_-	ECF transporter S component	NA	NA	NA	NA
WP_000476339.1\|1506112_1507027_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000476881.1\|1507083_1508001_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_061390271.1\|1508091_1508343_-	hypothetical protein	A0ZS61	Staphylococcus_virus	2.4e-25	100.0
WP_000528632.1\|1508552_1509110_-	hypothetical protein	W5R8Q1	Staphylococcus_phage	5.7e-104	100.0
WP_020444681.1\|1509834_1511289_-	CHAP domain-containing protein	B7T0L1	Staphylococcus_virus	1.0e-285	98.8
WP_000339141.1\|1511299_1511602_-\|holin	phage holin	A0A2I6PF56	Staphylococcus_phage	3.1e-48	100.0
WP_000466784.1\|1511737_1512037_-	DUF2951 domain-containing protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
1511821:1511838	attL	NA	NA	NA	NA
WP_000916020.1\|1512082_1512247_-	XkdX family protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
WP_001166599.1\|1512239_1512629_-	DUF2977 domain-containing protein	A0A2I6PER1	Staphylococcus_phage	2.2e-62	100.0
WP_031768055.1\|1512628_1514095_-\|plate	BppU family phage baseplate upper protein	A0A2I6PDE3	Staphylococcus_phage	2.4e-274	99.8
WP_031768053.1\|1514094_1516005_-	hypothetical protein	A0A2I6PDQ2	Staphylococcus_phage	0.0e+00	99.8
WP_000179860.1\|1516020_1516311_-	hypothetical protein	A0A2I6PF46	Staphylococcus_phage	2.1e-49	100.0
WP_000384474.1\|1516310_1517894_-	peptidase	A0A2I6PEQ5	Staphylococcus_phage	9.3e-309	100.0
WP_020444679.1\|1517902_1518727_-\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	1.2e-158	99.6
WP_088607378.1\|1518726_1524903_-\|tail	phage tail tape measure protein	A0A2I6PDS2	Staphylococcus_phage	0.0e+00	99.3
WP_000438833.1\|1524916_1525075_-	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
WP_000589165.1\|1525116_1525467_-	hypothetical protein	A0A2I6PDE6	Staphylococcus_phage	1.1e-55	100.0
WP_031768047.1\|1525524_1525980_-	Ig domain-containing protein	Q9B0D4	Staphylococcus_phage	2.0e-75	97.4
WP_031768043.1\|1526071_1526713_-\|tail	tail protein	A0A2I6PEP6	Staphylococcus_phage	5.5e-119	98.1
WP_001636966.1\|1526747_1527143_-	DUF3168 domain-containing protein	R4WAV1	Staphylococcus_phage	4.4e-66	99.2
WP_088607379.1\|1527143_1527545_-	hypothetical protein	R4WAN5	Staphylococcus_phage	2.3e-67	99.2
WP_000395498.1\|1527541_1527874_-	hypothetical protein	A0A2I6PES3	Staphylococcus_phage	4.1e-57	100.0
WP_000050973.1\|1527885_1528164_-\|head,tail	phage gp6-like head-tail connector protein	A0A2I6PEQ1	Staphylococcus_phage	2.1e-46	100.0
WP_001142734.1\|1528232_1529396_-\|capsid	phage major capsid protein	A0A2I6PEQ3	Staphylococcus_phage	1.2e-217	100.0
WP_000061866.1\|1529407_1530181_-\|protease	Clp protease ClpP	A0A2I6PEQ7	Staphylococcus_phage	2.4e-137	100.0
WP_001100664.1\|1530164_1531403_-\|portal	phage portal protein	A0A2I6PER5	Staphylococcus_phage	6.9e-235	100.0
WP_000153544.1\|1531407_1533099_-\|terminase	terminase large subunit	Q4ZD20	Staphylococcus_virus	0.0e+00	100.0
WP_000778933.1\|1533088_1533394_-\|terminase	terminase	A0A2I6PEQ6	Staphylococcus_phage	2.9e-49	100.0
WP_000160685.1\|1533520_1533835_-	HNH endonuclease	A0A2I6PED2	Staphylococcus_phage	8.5e-57	100.0
WP_000528512.1\|1533991_1534429_-	transcriptional regulator	A0A2I6PEN3	Staphylococcus_phage	7.9e-77	100.0
WP_088607380.1\|1534441_1535809_-	DEAD/DEAH box helicase	A0A2I6PE95	Staphylococcus_phage	3.0e-263	99.8
WP_000665203.1\|1535789_1536080_-	VRR-NUC domain-containing protein	A0A2I6PEN7	Staphylococcus_phage	6.5e-51	100.0
WP_011447017.1\|1536213_1536318_+	hypothetical protein	Q4ZCF8	Staphylococcus_virus	9.4e-13	100.0
WP_088607381.1\|1536420_1538868_-	hypothetical protein	R4WAL1	Staphylococcus_phage	0.0e+00	99.9
WP_000265258.1\|1538919_1539120_-	DUF1514 domain-containing protein	A0A2I6PF41	Staphylococcus_phage	2.9e-26	100.0
WP_001825321.1\|1539187_1539355_-	transcriptional activator RinB	A0A2I6PF16	Staphylococcus_phage	2.1e-22	100.0
WP_001125015.1\|1539342_1539543_-	hypothetical protein	A0A2I6PF22	Staphylococcus_phage	1.8e-28	100.0
WP_031893506.1\|1539517_1539706_-	DUF1381 domain-containing protein	Q4ZCG4	Staphylococcus_virus	6.1e-26	98.4
WP_088607382.1\|1539742_1540276_-	dUTP pyrophosphatase	A0A059T5A7	Staphylococcus_phage	4.3e-93	97.7
WP_001065085.1\|1540268_1540517_-	DUF1024 family protein	A0A0E3XC66	Staphylococcus_phage	1.2e-37	98.8
WP_072498756.1\|1540531_1540780_-	hypothetical protein	Q4ZCP1	Staphylococcus_virus	8.0e-42	96.3
WP_000235381.1\|1540788_1540989_-	hypothetical protein	A0A2I6PF32	Staphylococcus_phage	1.3e-29	100.0
WP_031893509.1\|1540991_1541249_-	DUF3310 domain-containing protein	A0A2I6PF10	Staphylococcus_phage	1.7e-42	98.8
WP_000113981.1\|1541248_1541650_-	PVL family protein	A0A2I6PF14	Staphylococcus_phage	1.2e-68	100.0
WP_001164629.1\|1541649_1541835_-	DUF3113 family protein	A0A2I6PEM8	Staphylococcus_phage	7.0e-27	100.0
WP_088607427.1\|1541847_1543800_-	DNA polymerase	A0A2I6PF18	Staphylococcus_phage	0.0e+00	98.6
WP_000645048.1\|1543867_1544425_-	DUF2815 family protein	A0A2I6PEP8	Staphylococcus_phage	1.8e-97	100.0
WP_088607383.1\|1544450_1545617_-	DUF2800 domain-containing protein	Q4ZCP7	Staphylococcus_virus	2.5e-218	99.0
WP_000985986.1\|1545613_1545976_-	hypothetical protein	Q4ZCP8	Staphylococcus_virus	2.2e-56	100.0
WP_000175000.1\|1545990_1546314_-	hypothetical protein	A0A2I6PDL5	Staphylococcus_phage	1.3e-52	100.0
WP_001285954.1\|1546392_1546554_-	DUF1270 domain-containing protein	A7TWM3	Staphylococcus_phage	8.6e-21	100.0
WP_001124160.1\|1546566_1546830_-	helix-turn-helix domain-containing protein	A7TWG0	Staphylococcus_phage	5.7e-46	100.0
WP_001097552.1\|1546854_1547070_-	hypothetical protein	A0A2I6PF01	Staphylococcus_phage	1.9e-31	100.0
WP_001128433.1\|1547124_1547490_+	hypothetical protein	A0A2I6PF07	Staphylococcus_phage	2.4e-63	100.0
WP_001025401.1\|1547458_1547704_-	DUF2829 domain-containing protein	A0A2I6PF15	Staphylococcus_phage	5.1e-41	100.0
WP_000642492.1\|1547759_1547969_+	hypothetical protein	W5R9J5	Staphylococcus_phage	1.2e-30	100.0
WP_000939498.1\|1547958_1548102_-	hypothetical protein	W5R8I6	Staphylococcus_phage	2.5e-16	100.0
WP_000435360.1\|1548116_1548560_-	hypothetical protein	W5R971	Staphylococcus_phage	1.5e-75	100.0
WP_000333485.1\|1548577_1548802_-	DUF739 family protein	A0A2I6PE94	Staphylococcus_phage	2.7e-36	100.0
WP_001089477.1\|1548963_1549344_+	helix-turn-helix domain-containing protein	A0A2I6PE55	Staphylococcus_phage	1.5e-63	99.2
WP_001558059.1\|1549365_1549824_+	hypothetical protein	B2ZYU2	Staphylococcus_phage	3.5e-83	99.3
WP_000755719.1\|1549841_1550276_+	hypothetical protein	A0A2D1G561	Staphylococcus_phage	2.8e-26	100.0
WP_000449655.1\|1550304_1550700_+	hypothetical protein	A0A2I6PEJ7	Staphylococcus_phage	3.8e-70	100.0
WP_001013104.1\|1550789_1550936_+	hypothetical protein	A0A2I6PEK8	Staphylococcus_phage	1.1e-14	89.6
WP_088607384.1\|1550932_1551547_-	ATPase	A7TW88	Staphylococcus_phage	1.3e-106	99.5
WP_088607385.1\|1551672_1552878_+\|integrase	site-specific integrase	A0A2I6PEZ6	Staphylococcus_phage	3.5e-223	99.8
WP_001793477.1\|1552920_1554948_-	hypothetical protein	B5WZK7	Staphylococcus_phage	1.1e-112	96.2
WP_001793476.1\|1554959_1555868_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000987769.1\|1556112_1557864_-	HAMP domain-containing protein	A0A1V0SGX0	Hokovirus	1.7e-21	33.6
1557087:1557104	attR	NA	NA	NA	NA
WP_000064078.1\|1557844_1558570_-	response regulator transcription factor	W8CYM9	Bacillus_phage	3.5e-45	43.0

DBSCAN-SWA_5

1615029 : 1623359

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001213908.1\|1615029_1615815_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
WP_000924220.1\|1615940_1616831_-	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	3.4e-26	36.0
WP_001062177.1\|1616840_1618187_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
WP_000683932.1\|1618300_1619401_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
WP_000624585.1\|1619403_1620081_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_001283055.1\|1620211_1621318_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_001217235.1\|1621541_1623359_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	7.9e-54	36.0

DBSCAN-SWA_6

1692968 : 1702011

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364542.1\|1692968_1693487_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
WP_000594997.1\|1693508_1695782_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	3.1e-63	29.1
WP_000749795.1\|1695984_1698264_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_001160682.1\|1698538_1698799_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_001112045.1\|1698817_1699957_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001019178.1\|1699979_1701005_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005768.1\|1701006_1702011_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_7

1827331 : 1904861

Staphylococcus_phage(94.83%)

protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_088607392.1\|1827331_1833892_-	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	2.9e-300	96.7
WP_000836465.1\|1834217_1834529_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
WP_001108725.1\|1834550_1836971_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.7
WP_001025071.1\|1837261_1838443_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	6.2e-217	99.7
WP_000526539.1\|1838552_1839506_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_000764419.1\|1839502_1840066_+	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
WP_000757543.1\|1840185_1840587_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000266096.1\|1841160_1841988_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001790712.1\|1841990_1842110_-	hypothetical protein	NA	NA	NA	NA
WP_001196354.1\|1842221_1843223_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
WP_001008549.1\|1843344_1843809_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.5e-70	100.0
WP_001159035.1\|1843821_1845003_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.7e-227	100.0
WP_000493886.1\|1845013_1845646_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	6.4e-112	99.0
WP_000384184.1\|1845652_1846684_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.6e-197	99.7
WP_001261671.1\|1847176_1848679_-	pyridine nucleotide-disulfide oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	1.5e-29	98.6
WP_000221179.1\|1849201_1849516_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	2.0e-53	100.0
WP_000989116.1\|1849515_1850808_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	1.1e-227	99.8
WP_001032833.1\|1850894_1851749_-	autolysin	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000384171.1\|1852024_1852249_-	hypothetical protein	NA	NA	NA	NA
WP_000671052.1\|1852447_1852918_+	RNA polymerase sigma factor SigS	A0A2H4PQT5	Staphylococcus_phage	1.0e-82	99.4
WP_001153742.1\|1853030_1853474_+	competence protein ComK	NA	NA	NA	NA
WP_001030469.1\|1853460_1853904_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
WP_001168907.1\|1854199_1854835_+\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001096494.1\|1855274_1855988_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_000091445.1\|1856247_1856550_+	hypothetical protein	NA	NA	NA	NA
WP_001200542.1\|1856805_1857171_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
WP_000623476.1\|1857167_1857521_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	2.0e-22	98.3
WP_000453314.1\|1857903_1858737_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	5.4e-159	100.0
WP_000366158.1\|1858948_1859857_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	1.7e-137	99.0
WP_000933822.1\|1859981_1861175_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_000109910.1\|1861546_1863139_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.8
WP_016169057.1\|1863516_1864263_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	2.2e-143	99.2
WP_000672013.1\|1864267_1864741_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	7.2e-84	98.7
WP_000718107.1\|1864806_1865064_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000778532.1\|1865060_1866062_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	2.8e-186	97.9
WP_000348356.1\|1866066_1867545_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.6e-281	97.0
WP_072419835.1\|1867703_1868159_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	5.7e-78	97.3
WP_001793444.1\|1868461_1869112_+	calcium-binding protein	A0A2H4PQM8	Staphylococcus_phage	3.0e-56	99.1
WP_000070649.1\|1869192_1870188_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	4.2e-73	97.2
WP_000669017.1\|1870261_1870888_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	3.6e-91	94.7
WP_000627541.1\|1870928_1871270_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	8.1e-53	92.0
WP_000414202.1\|1871370_1871943_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	3.3e-22	89.7
WP_000864135.1\|1872230_1872698_-	ImmA/IrrE family metallo-endopeptidase	A0A2H4PQN8	Staphylococcus_phage	3.3e-65	100.0
WP_000375477.1\|1873071_1873248_-	hypothetical protein	NA	NA	NA	NA
WP_000070814.1\|1873258_1873642_-	hypothetical protein	NA	NA	NA	NA
WP_001549059.1\|1874245_1874389_-\|transposase	transposase	A0A2H4PQU1	Staphylococcus_phage	6.4e-20	100.0
WP_001791893.1\|1874805_1874907_+	hypothetical protein	NA	NA	NA	NA
WP_088607393.1\|1881113_1882313_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	4.6e-228	99.5
WP_001793440.1\|1882305_1884045_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.4e-289	100.0
WP_001791797.1\|1884025_1884160_-	hypothetical protein	NA	NA	NA	NA
WP_001038688.1\|1884224_1884944_-\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.1e-131	100.0
WP_088607394.1\|1885094_1885811_-\|protease	serine protease SplE	A0A2H4PQN5	Staphylococcus_phage	5.4e-131	99.6
WP_011447030.1\|1885912_1886020_+	hypothetical protein	NA	NA	NA	NA
WP_001038704.1\|1885968_1886688_-\|protease	serine protease SplD	A0A2H4PQP9	Staphylococcus_phage	4.6e-130	99.6
WP_001038859.1\|1886808_1887528_-\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	3.2e-131	99.6
WP_001039444.1\|1887585_1888308_-\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	6.4e-132	100.0
WP_001005059.1\|1888432_1889140_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	7.7e-130	99.6
WP_001092763.1\|1890103_1890670_+	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	3.3e-99	100.0
WP_000586140.1\|1891143_1891842_-	hypothetical protein	A0A2H4PQH0	Staphylococcus_phage	3.8e-113	94.4
WP_000581552.1\|1891838_1892600_-	lantibiotic immunity ABC transporter MutE/EpiE family permease subunit	A0A2H4PQH2	Staphylococcus_phage	4.4e-131	100.0
WP_001096791.1\|1892596_1893289_-	lantibiotic protection ABC transporter ATP-binding subunit	A0A2H4PQG7	Staphylococcus_phage	6.2e-124	100.0
WP_000691541.1\|1893311_1894685_-	S8 family serine peptidase	A0A2H4PQH1	Staphylococcus_phage	2.9e-258	100.0
WP_000504439.1\|1894694_1895213_-	enterotoxin	A0A2H4PQG9	Staphylococcus_phage	2.0e-95	100.0
WP_000566596.1\|1895228_1896473_-	lanthionine synthetase C family protein	A0A2H4PQH9	Staphylococcus_phage	5.1e-238	100.0
WP_001092607.1\|1896465_1899459_-	lantibiotic dehydratase	A0A2H4PQG8	Staphylococcus_phage	0.0e+00	97.0
WP_000416756.1\|1899523_1899667_-	gallidermin/nisin family lantibiotic	A0A2H4PQH4	Staphylococcus_phage	5.3e-14	80.9
WP_000416759.1\|1900403_1900547_-	gallidermin/nisin family lantibiotic	NA	NA	NA	NA
WP_000782464.1\|1900788_1901772_-	bi-component leukocidin LukED subunit D	A0A2H4PQH7	Staphylococcus_phage	2.3e-185	99.1
WP_000473596.1\|1901773_1902709_-	beta-channel forming cytolysin	A0A2H4PQI5	Staphylococcus_phage	1.4e-174	100.0
WP_001086056.1\|1903604_1904060_+	hypothetical protein	Q4ZCB9	Staphylococcus_virus	6.3e-61	76.2
WP_000206350.1\|1904072_1904861_+	DUF1828 domain-containing protein	A0A2H4PQI0	Staphylococcus_phage	5.3e-140	95.8

DBSCAN-SWA_8

1986266 : 2088715

115

Staphylococcus_phage(88.16%)

tail,capsid,holin,integrase,tRNA,terminase,transposase,head,protease,portal

attL 2035617:2035634|attR 2084744:2084761

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000027917.1\|1986266_1987724_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_000170162.1\|1987725_1988028_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_000957020.1\|1988394_1989933_+	sodium/proline symporter PutP	NA	NA	NA	NA
WP_000831697.1\|1990021_1991221_-	CamS family sex pheromone protein	NA	NA	NA	NA
WP_000774565.1\|1991233_1993237_-	NAD-dependent DNA ligase LigA	A0A0K2QQN8	Ralstonia_phage	5.8e-114	36.1
WP_000992921.1\|1993240_1995433_-	DNA helicase PcrA	A7KV33	Bacillus_phage	1.0e-135	42.2
WP_000272070.1\|1995429_1996122_-	heptaprenylglyceryl phosphate synthase	NA	NA	NA	NA
WP_001165363.1\|1996293_1996596_-	hypothetical protein	NA	NA	NA	NA
WP_000572878.1\|1996704_1998000_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.6e-16	32.9
WP_000827761.1\|1998860_2000027_+\|protease	cysteine protease staphopain A	NA	NA	NA	NA
WP_000434534.1\|2000057_2000384_+	staphostatin A	NA	NA	NA	NA
WP_000669861.1\|2000675_2000849_-	NETI motif-containing protein	NA	NA	NA	NA
WP_000011542.1\|2000829_2001432_-	DUF2179 domain-containing protein	NA	NA	NA	NA
WP_000040866.1\|2001702_2002524_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	2.3e-69	52.7
WP_000284431.1\|2002516_2003986_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	4.5e-108	45.1
WP_000897635.1\|2004169_2005246_+	nitric oxide synthase oxygenase	NA	NA	NA	NA
WP_001177816.1\|2005265_2006060_+	prephenate dehydratase	NA	NA	NA	NA
WP_001802312.1\|2006131_2006239_+	hypothetical protein	NA	NA	NA	NA
WP_000323164.1\|2006249_2007812_-	SLC13 family permease	NA	NA	NA	NA
WP_000275710.1\|2008016_2009114_-	pectate lyase	U5PWM6	Bacillus_phage	1.6e-46	34.3
WP_000149686.1\|2009485_2010046_+	cysteine hydrolase	G3MA16	Bacillus_virus	2.0e-32	41.2
WP_001140871.1\|2010098_2011028_+	manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
WP_001790680.1\|2011222_2011396_-	hypothetical protein	NA	NA	NA	NA
WP_001021214.1\|2011447_2012827_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_000181322.1\|2012946_2013975_-	lactonase family protein	NA	NA	NA	NA
WP_000205106.1\|2014244_2014646_+	YolD-like family protein	U3PG23	Staphylococcus_phage	6.0e-23	42.9
WP_000267034.1\|2015218_2015392_-	hypothetical protein	NA	NA	NA	NA
WP_001188043.1\|2015842_2016883_+	linear amide C-N hydrolase	NA	NA	NA	NA
WP_000713072.1\|2016939_2017782_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_001033971.1\|2017778_2018336_-	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_000966288.1\|2018395_2018920_-	membrane protein	NA	NA	NA	NA
WP_000182842.1\|2019040_2019604_+	thioredoxin family protein	NA	NA	NA	NA
WP_088607395.1\|2019669_2020410_-	phenol-soluble modulin export ABC transporter permease subunit PmtD	NA	NA	NA	NA
WP_000763048.1\|2020409_2021282_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtC	A0A2H4PQG7	Staphylococcus_phage	6.1e-28	35.2
WP_000645726.1\|2021278_2021959_-	phenol-soluble modulin export ABC transporter permease subunit PmtB	NA	NA	NA	NA
WP_000991301.1\|2021959_2022856_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtA	A0A2H4PQG7	Staphylococcus_phage	1.1e-16	30.2
WP_000691584.1\|2022852_2023233_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000681968.1\|2023491_2023668_-	hypothetical protein	NA	NA	NA	NA
WP_000990056.1\|2023910_2024009_-	hypothetical protein	NA	NA	NA	NA
WP_001068523.1\|2024208_2025495_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_001792928.1\|2026119_2027868_-	MAP domain-containing protein	NA	NA	NA	NA
WP_000669791.1\|2028825_2029005_+	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	1.4e-24	98.3
WP_001791826.1\|2029315_2029576_+	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
WP_000702263.1\|2029628_2029979_-	complement inhibitor SCIN-A	A0A1P8L6B0	Staphylococcus_phage	7.5e-54	100.0
WP_001110820.1\|2030490_2030787_-	peptidoglycan hydrolase	A0A1P8L6B4	Staphylococcus_phage	1.6e-49	95.9
WP_000920038.1\|2031476_2031968_-	staphylokinase	A0A1W6JQ12	Staphylococcus_phage	4.7e-86	99.4
WP_000861025.1\|2032158_2032914_-	CHAP domain-containing protein	D2JLG5	Staphylococcus_phage	7.6e-152	99.6
WP_000611512.1\|2032925_2033180_-\|holin	phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
WP_031762631.1\|2033231_2033339_+	hypothetical protein	NA	NA	NA	NA
WP_011447039.1\|2033391_2033568_-\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	2.2e-22	98.3
WP_000750412.1\|2033676_2034450_-	staphylococcal enterotoxin type A	A0A1X9H080	Staphylococcus_phage	1.1e-145	100.0
WP_000340977.1\|2034822_2035197_-	hypothetical protein	G4KNR3	Staphylococcus_phage	3.3e-39	100.0
WP_001262621.1\|2035252_2035540_-	hypothetical protein	A0A1X9H0N7	Staphylococcus_phage	7.6e-44	100.0
WP_001000058.1\|2035585_2035738_-	hypothetical protein	A0A1W6JPL6	Staphylococcus_phage	7.6e-19	100.0
2035617:2035634	attL	NA	NA	NA	NA
WP_000582130.1\|2035730_2039513_-	hypothetical protein	A0A1X9H096	Staphylococcus_phage	0.0e+00	99.4
WP_001154317.1\|2039528_2041019_-\|tail	phage tail protein	R9QST9	Staphylococcus_phage	3.1e-298	100.0
WP_001133533.1\|2041018_2045668_-\|tail	phage tail tape measure protein	A0A1V0E5H1	Staphylococcus_phage	0.0e+00	94.7
WP_000570353.1\|2045723_2045846_-	hypothetical protein	D2JLF6	Staphylococcus_phage	6.9e-15	100.0
WP_000442601.1\|2045905_2046352_-	hypothetical protein	D2JLF5	Staphylococcus_phage	5.4e-73	100.0
WP_000570652.1\|2046416_2047370_-\|tail	phage tail protein	A7TWD0	Staphylococcus_phage	6.2e-175	100.0
WP_088607396.1\|2047370_2047751_-	hypothetical protein	D2JLF3	Staphylococcus_phage	1.4e-66	98.4
WP_000501244.1\|2047747_2048125_-	HK97 gp10 family phage protein	D2JLF2	Staphylococcus_phage	1.1e-61	100.0
WP_000975314.1\|2048124_2048460_-\|head,tail	head-tail adaptor protein	A7TWC7	Staphylococcus_phage	1.1e-59	100.0
WP_001177483.1\|2048446_2048779_-\|head,tail	phage head-tail adapter protein	D2JLF0	Staphylococcus_phage	2.1e-58	100.0
WP_001252099.1\|2048787_2048946_-	hypothetical protein	D2JLE9	Staphylococcus_phage	3.2e-20	100.0
WP_000849950.1\|2048981_2050229_-\|capsid	phage major capsid protein	A7TWC4	Staphylococcus_phage	5.0e-209	100.0
WP_000032525.1\|2050316_2050901_-\|head,protease	HK97 family phage prohead protease	D2JLE7	Staphylococcus_phage	9.8e-107	100.0
WP_011447040.1\|2050893_2052084_-\|portal	phage portal protein	D2JLE6	Staphylococcus_phage	1.8e-224	100.0
WP_000644964.1\|2052149_2052389_-	membrane protein	A7TWC1	Staphylococcus_phage	1.2e-34	98.7
WP_000133304.1\|2052363_2054058_-\|terminase	phage terminase large subunit	D2JLE4	Staphylococcus_phage	0.0e+00	100.0
WP_000919026.1\|2054060_2054528_-\|terminase	phage terminase small subunit P27 family	D2JLE3	Staphylococcus_phage	1.1e-81	100.0
WP_088607429.1\|2054656_2055001_-	HNH endonuclease	D2JLE2	Staphylococcus_phage	7.9e-64	99.1
WP_000406191.1\|2055016_2055469_-	nucleoside triphosphate pyrophosphohydrolase family protein	D2JLE1	Staphylococcus_phage	1.4e-79	100.0
WP_000282755.1\|2055583_2056054_-	hypothetical protein	D2JLE0	Staphylococcus_phage	1.7e-69	99.3
WP_001570807.1\|2056076_2056277_-	DUF1514 domain-containing protein	A0A2I6PDV9	Staphylococcus_phage	4.0e-28	98.5
WP_001005262.1\|2056276_2056927_-	hypothetical protein	D2JLD8	Staphylococcus_phage	8.9e-117	100.0
WP_000595265.1\|2057085_2057235_-	transcriptional activator RinB	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
WP_088607397.1\|2057248_2057563_-	hypothetical protein	A0A2I6PDG3	Staphylococcus_phage	5.6e-32	100.0
WP_000401978.1\|2057575_2057980_-	RusA family crossover junction endodeoxyribonuclease	A0A0H3U2W2	Staphylococcus_phage	6.9e-67	91.0
WP_000338527.1\|2057988_2058207_-	hypothetical protein	A0A1P8L6E4	Staphylococcus_phage	4.0e-37	98.6
WP_000148328.1\|2058213_2059107_-	DnaD domain-containing protein	A0A0E3TAG7	Staphylococcus_phage	1.6e-137	97.6
WP_000934765.1\|2059136_2059607_-	single-stranded DNA-binding protein	A0A1P8L6D9	Staphylococcus_phage	7.7e-78	96.2
WP_072353921.1\|2059607_2060225_-	MBL fold metallo-hydrolase	A0A1W6JPL3	Staphylococcus_phage	1.3e-85	98.1
WP_000138475.1\|2060305_2061226_-	recombinase	A0A2I6PDH5	Staphylococcus_phage	2.3e-166	100.0
WP_025175236.1\|2061227_2063171_-	AAA family ATPase	A0A2I6PDH3	Staphylococcus_phage	0.0e+00	99.1
WP_001205732.1\|2063179_2063443_-	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
WP_000291488.1\|2063451_2063712_-	DUF1108 family protein	A0A2I6PDH1	Staphylococcus_phage	2.6e-43	100.0
WP_000066020.1\|2063804_2063966_-	DUF1270 domain-containing protein	A0A2I6PDF7	Staphylococcus_phage	1.9e-20	100.0
WP_001120197.1\|2063962_2064283_-	DUF771 domain-containing protein	A0A2I6PDH6	Staphylococcus_phage	1.5e-56	100.0
WP_000275058.1\|2064341_2064974_+	hypothetical protein	A7TW95	Staphylococcus_phage	1.5e-113	100.0
WP_000939496.1\|2064988_2065129_-	hypothetical protein	A0A2I6PDG0	Staphylococcus_phage	1.9e-16	100.0
WP_001148861.1\|2065159_2065357_-	hypothetical protein	A0A1W6JPV3	Staphylococcus_phage	1.2e-24	100.0
WP_001148337.1\|2065372_2066122_-	antirepressor	Q8SDM9	Staphylococcus_phage	4.4e-136	99.6
WP_000351243.1\|2066178_2066718_+	hypothetical protein	A7TW92	Staphylococcus_phage	1.7e-97	100.0
WP_000435341.1\|2066741_2067002_-	transcriptional regulator	A7TW91	Staphylococcus_phage	2.7e-40	100.0
WP_000338186.1\|2067019_2067244_-	DUF739 family protein	A7TW90	Staphylococcus_phage	4.5e-36	100.0
WP_001208482.1\|2067402_2068173_+	helix-turn-helix domain-containing protein	A0A1P8L6G7	Staphylococcus_phage	6.2e-141	100.0
WP_001033320.1\|2068368_2069097_+	staphylococcal enterotoxin type Q	A0EX09	Staphylococcus_phage	2.3e-28	34.9
WP_000733771.1\|2069120_2069849_+	staphylococcal enterotoxin type K	A0EX09	Staphylococcus_phage	6.4e-23	32.3
WP_000857182.1\|2069932_2070970_+\|integrase	site-specific integrase	E9LT82	Staphylococcus_phage	2.6e-195	100.0
WP_000595401.1\|2072088_2073105_-	bi-component leukocidin LukGH subunit G	A0A2I6PER8	Staphylococcus_phage	2.3e-26	29.3
WP_000791417.1\|2073126_2074179_-	bi-component leukocidin LukGH subunit H	A0A2I6PDF3	Staphylococcus_phage	1.6e-35	32.1
WP_000206623.1\|2074614_2075838_+	ArgE/DapE family deacylase	NA	NA	NA	NA
WP_000812008.1\|2076209_2077055_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_088607398.1\|2077116_2078013_-	iron-hydroxamate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000195429.1\|2078064_2079237_-\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_001045079.1\|2079523_2080831_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_000022887.1\|2081684_2082128_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000195429.1\|2082405_2083578_+\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_088607430.1\|2083604_2084003_-	hypothetical protein	NA	NA	NA	NA
WP_001293059.1\|2084319_2084910_-\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	1.2e-96	94.7
2084744:2084761	attR	NA	NA	NA	NA
WP_000128898.1\|2084906_2085119_-	hypothetical protein	Q4ZE86	Staphylococcus_phage	1.1e-23	74.3
WP_000240642.1\|2085820_2087437_-	chaperonin GroEL	A0A240F779	uncultured_virus	3.4e-157	54.7
WP_000917289.1\|2087512_2087797_-	co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2
WP_000197635.1\|2087971_2088715_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP017115

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection