CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP022021	Listeria monocytogenes strain FDA709873-33 plasmid pCFSAN021445, complete sequence	0 crisprs	csa3,cas5	0	0	2	0
NZ_CP022020	Listeria monocytogenes strain FDA709873-33 chromosome, complete genome	2 crisprs	DinG,cas3,WYL,casR,RT,DEDDh,csa3	0	0	10	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1195 : 21815

Streptococcus_phage(50.0%)

transposase,protease,integrase

attL 1933:1951|attR 21853:21871

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002319817.1\|1195_1876_-\|transposase	IS6-like element ISS1N family transposase	A0A1X9I6C6	Streptococcus_phage	2.5e-109	84.1
1933:1951	attL	NA	NA	NA	NA
WP_023559433.1\|2042_3161_+\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A0S1WEW6	Vibrio_phage	8.7e-11	27.1
WP_023559432.1\|3307_3937_+	Abi family protein	M1PS09	Streptococcus_phage	3.5e-25	35.1
WP_023559431.1\|3928_4864_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	7.1e-83	51.0
WP_003725285.1\|5557_6502_-	AAA domain-containing protein	A7KV75	Bacillus_phage	9.2e-46	36.8
WP_003750115.1\|6502_6691_-	hypothetical protein	NA	NA	NA	NA
WP_003725286.1\|6761_7271_-	hypothetical protein	NA	NA	NA	NA
WP_003725287.1\|7510_8374_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_003725288.1\|8769_9126_-	glyoxalase	NA	NA	NA	NA
WP_003725292.1\|10051_10396_-	quaternary ammonium compound efflux SMR transporter BcrC	NA	NA	NA	NA
WP_003725293.1\|10413_10731_-	quaternary ammonium compound efflux SMR transporter BcrB	NA	NA	NA	NA
WP_003725294.1\|10742_11282_-	efflux transporter transcriptional regulator BcrA	NA	NA	NA	NA
WP_157671086.1\|11928_12063_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_023559430.1\|12132_13746_-	DUF1738 domain-containing protein	NA	NA	NA	NA
WP_002319817.1\|13809_14490_-\|transposase	IS6-like element ISS1N family transposase	A0A1X9I6C6	Streptococcus_phage	2.5e-109	84.1
WP_003725297.1\|14489_14993_-	AAA family ATPase	NA	NA	NA	NA
WP_003725298.1\|14985_16422_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A2H4JGQ6	uncultured_Caudovirales_phage	9.4e-18	24.8
WP_003725299.1\|16580_17180_+	recombinase family protein	I1ZBD6	Salisaeta_icosahedral_phage	1.8e-15	31.8
WP_003726380.1\|17453_17813_+	winged helix-turn-helix transcriptional regulator	E4ZFI8	Streptococcus_phage	5.4e-23	48.2
WP_003726381.1\|17809_19927_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	5.3e-235	62.6
WP_023558764.1\|20571_21075_-\|integrase	tyrosine-type recombinase/integrase	D2XR58	Bacillus_phage	6.6e-19	35.9
WP_003726384.1\|21134_21815_+\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	1.2e-92	69.0
21853:21871	attR	NA	NA	NA	NA

DBSCAN-SWA_2

83729 : 124801

Streptococcus_phage(31.25%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002389568.1\|83729_84410_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	2.6e-119	90.7
WP_003728481.1\|85033_86398_+	FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	1.9e-07	23.5
WP_003728480.1\|86643_87513_-	glycine betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003728477.1\|88383_89148_+\|transposase	transposase	NA	NA	NA	NA
WP_003728476.1\|89610_91494_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	5.6e-87	35.3
WP_002319817.1\|91613_92294_-\|transposase	IS6-like element ISS1N family transposase	A0A1X9I6C6	Streptococcus_phage	2.5e-109	84.1
WP_003728473.1\|94587_95799_-	hypothetical protein	NA	NA	NA	NA
WP_003728472.1\|96049_96613_-	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	2.0e-40	51.1
WP_031644250.1\|97186_97552_+	DUF3221 domain-containing protein	NA	NA	NA	NA
WP_031641532.1\|97572_98871_+	hypothetical protein	NA	NA	NA	NA
WP_003725288.1\|99270_99627_-	glyoxalase	NA	NA	NA	NA
WP_009917198.1\|100552_100897_-	quaternary ammonium compound efflux SMR transporter BcrC	NA	NA	NA	NA
WP_003725293.1\|100914_101232_-	quaternary ammonium compound efflux SMR transporter BcrB	NA	NA	NA	NA
WP_003725294.1\|101243_101783_-	efflux transporter transcriptional regulator BcrA	NA	NA	NA	NA
WP_031644247.1\|102223_102463_+	hypothetical protein	NA	NA	NA	NA
WP_003728469.1\|104536_107452_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	1.9e-174	36.7
WP_003728468.1\|107455_108010_-	recombinase family protein	A0A0F7LA37	Escherichia_phage	7.0e-38	53.4
WP_003728467.1\|108289_108649_+	Cd(II)-sensing metalloregulatory transcriptional repressor CadC	E4ZFI8	Streptococcus_phage	3.1e-26	50.0
WP_003728466.1\|108648_110784_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	1.6e-247	64.5
WP_003728465.1\|110976_111318_-	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_003728464.1\|111311_111554_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_003728463.1\|111614_111866_-	hypothetical protein	NA	NA	NA	NA
WP_003728462.1\|111996_112323_+	hypothetical protein	A0A2K9V3N4	Faecalibacterium_phage	3.2e-06	40.8
WP_003731676.1\|112322_112985_+	DUF2786 domain-containing protein	NA	NA	NA	NA
WP_003769263.1\|113003_113381_+	DUF3850 domain-containing protein	C9E2N9	Enterococcus_phage	2.2e-14	55.1
WP_023553717.1\|113779_114028_+	hypothetical protein	NA	NA	NA	NA
WP_003728519.1\|114149_114398_+	hypothetical protein	NA	NA	NA	NA
WP_003728518.1\|114398_114824_+	hypothetical protein	NA	NA	NA	NA
WP_003728517.1\|114827_115550_+	CRISPR-associated protein Cas5	NA	NA	NA	NA
WP_003769259.1\|116370_117240_-\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	7.1e-69	51.1
WP_088518325.1\|117208_117508_-	hypothetical protein	Q6J1X3	Lactobacillus_phage	8.8e-11	43.4
WP_003728513.1\|118031_119798_+	hypothetical protein	NA	NA	NA	NA
WP_003728512.1\|119809_120550_+	hypothetical protein	NA	NA	NA	NA
WP_003728511.1\|120837_121446_+	recombinase family protein	A0A1W5LU24	Ralstonia_phage	1.0e-21	42.9
WP_003728510.1\|121435_121663_+	hypothetical protein	NA	NA	NA	NA
WP_151305387.1\|121769_122003_-	hypothetical protein	NA	NA	NA	NA
WP_003728509.1\|122022_122259_+	helix-turn-helix transcriptional regulator	A0A097PBE6	Streptococcus_pyogenes_phage	6.7e-14	53.4
WP_003728507.1\|122686_124801_+\|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	3.4e-117	39.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP022020

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP022020_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022020_1

511715-512299

Orphan

Consensus_repeat	Method
GATGTAAGTAATTTTGATACNAGTTCAGTAACTNATATG	CRT

7 spacers

The CRISPR arrays of NZ_CP022020_1

>merge|NZ_CP022020|1|511715-512299|CRT
GATTTGAGTGGTCTTGATACTAGTGCGGTAACTACTATGTGGGATATGTTTAACAGCTGTAGGGCACTTGAGGAACTGGATGTAAGTAATTTTGATACGAGTTCAGTAACTAATATGTCTTACATGTTTTATGATAATAGAAACCTTGAGGTGCTGGATGTAAGCAACCTTGATACCGGTTCAGTAACTAATATGTATGCCATGTTTGAAGATTGTACTAGTCTTGAAGAGCTGGATGTAAGTAATTTTGATACGAGTTCAGTAACTGATATGTATAGAGTGTTTAATGGCTGTGAAAAACTGAAGAAACTAGATGTAAGTAATTTCGATACCAGTTCCGCTACTGCAATGGTTCAAATGTTTAGAAATTGTAGCGCCCTTGAGAAGTTGGATGTAAGTAATTTTAATACGAGCTTAGTAACTGATATGCGTGCCATGTTTGCTGGTTGTACTAGTCTTGAAGCGTTAGATGTAAGTAATTTTGATACGAGTTCAGTAACTAATATGGCTGCCATGTTTTCTGATAATGAAAAACTGGAGAAGCTTGATTTAAGTACCTTTGATACCAGTTCAGTGACTAACATG

>NZ_CP022020|1|1|511715-512299|CRT
GATTTGAGTGGTCTTGATACTAGTGCGGTAACTACTATG	TGGGATATGTTTAACAGCTGTAGGGCACTTGAGGAACTG
GATGTAAGTAATTTTGATACGAGTTCAGTAACTAATATG	TCTTACATGTTTTATGATAATAGAAACCTTGAGGTGCTG
GATGTAAGCAACCTTGATACCGGTTCAGTAACTAATATG	TATGCCATGTTTGAAGATTGTACTAGTCTTGAAGAGCTG
GATGTAAGTAATTTTGATACGAGTTCAGTAACTGATATG	TATAGAGTGTTTAATGGCTGTGAAAAACTGAAGAAACTA
GATGTAAGTAATTTCGATACCAGTTCCGCTACTGCAATG	GTTCAAATGTTTAGAAATTGTAGCGCCCTTGAGAAGTTG
GATGTAAGTAATTTTAATACGAGCTTAGTAACTGATATG	CGTGCCATGTTTGCTGGTTGTACTAGTCTTGAAGCGTTA
GATGTAAGTAATTTTGATACGAGTTCAGTAACTAATATG	GCTGCCATGTTTTCTGATAATGAAAAACTGGAGAAGCTT
GATTTAAGTACCTTTGATACCAGTTCAGTGACTAACATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022020.1\|WP_003740428.1\|500747_502343_+\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225306
NZ_CP022020.1\|WP_003728986.1\|518521_520222_+\|oleate-hydratase	unknown	unknown	gnl\|CDD\|227060
NZ_CP022020.1\|WP_023550311.1\|507038_508577_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|368260
NZ_CP022020.1\|WP_003725186.1\|496335_498495_-\|transglutaminase	unknown	unknown	gnl\|CDD\|376628
NZ_CP022020.1\|WP_003725189.1\|502477_503761_+\|cytosine-permease	unknown	unknown	gnl\|CDD\|271377
NZ_CP022020.1\|WP_003733207.1\|517851_518412_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379534
NZ_CP022020.1\|WP_026747116.1\|513262_515020_+\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP022020.1\|WP_003725199.1\|516472_516739_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022020.1\|WP_003728092.1\|504854_506405_+\|hydantoinase/oxoprolinase-family-protein	unknown	unknown	gnl\|CDD\|223223
NZ_CP022020.1\|WP_003728093.1\|503761_504862_+\|DUF917-domain-containing-protein	unknown	unknown	gnl\|CDD\|226065
NZ_CP022020.1\|WP_003725208.1\|520372_521476_+\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	unknown	unknown	gnl\|CDD\|237717
NZ_CP022020.1\|WP_023550313.1\|508840_510922_+\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP022020.1\|WP_003721252.1\|515085_515559_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022020.1\|WP_003727318.1\|516091_516397_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|273478
NZ_CP022020.1\|WP_003721242.1\|499644_500592_-\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NZ_CP022020.1\|WP_003725209.1\|521565_522045_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226231
NZ_CP022020.1\|WP_003721253.1\|515578_516064_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022020.1\|WP_003721271.1\|522202_522568_+\|heme-oxygenase-IsdG	unknown	unknown	gnl\|CDD\|183970
NZ_CP022020.1\|WP_009929138.1\|498491_499640_-\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635
NZ_CP022020.1\|WP_003734632.1\|495463_496219_-\|DUF4866-family-protein	unknown	unknown	gnl\|CDD\|379782

Protein	Function_ID	Function_description	E-value
NZ_CP022020.1\|WP_003740428.1\|500747_502343_+\|PucR-family-transcriptional-regulator	gnl\|CDD\|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	2.42853e-59
NZ_CP022020.1\|WP_003728986.1\|518521_520222_+\|oleate-hydratase	gnl\|CDD\|227060	COG4716, COG4716, Myosin-crossreactive antigen [Function unknown].	0
NZ_CP022020.1\|WP_023550311.1\|507038_508577_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|368260	pfam05043, Mga, Mga helix-turn-helix domain. M regulator protein trans-acting positive regulator (Mga) is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This domain is found in the centre of the Mga proteins. This family also contains a number of bacterial RofA transcriptional regulators that seem to be largely restricted to streptococci. These proteins have been shown to regulate the expression of important bacterial adhesins. This is presumably a DNA-binding domain.	1.01429e-19
NZ_CP022020.1\|WP_003725186.1\|496335_498495_-\|transglutaminase	gnl\|CDD\|376628	pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine, and aspartate residues that form the catalytic triad in the structurally characterized transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologs of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.	4.40206e-28
NZ_CP022020.1\|WP_003725189.1\|502477_503761_+\|cytosine-permease	gnl\|CDD\|271377	cd11484, SLC-NCS1sbd_CobB-like, nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain. This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).	2.40318e-96
NZ_CP022020.1\|WP_003733207.1\|517851_518412_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|379534	pfam14278, TetR_C_8, Transcriptional regulator C-terminal region. This domain is a tetracycline repressor, domain 2, or C-terminus.	2.23521e-25
NZ_CP022020.1\|WP_026747116.1\|513262_515020_+\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	5.49851e-29
NZ_CP022020.1\|WP_003721271.1\|522202_522568_+\|heme-oxygenase-IsdG	gnl\|CDD\|183970	PRK13316, PRK13316, heme oxygenase IsdG.	3.55164e-70
NZ_CP022020.1\|WP_003728092.1\|504854_506405_+\|hydantoinase/oxoprolinase-family-protein	gnl\|CDD\|223223	COG0145, HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	1.15698e-106
NZ_CP022020.1\|WP_003728093.1\|503761_504862_+\|DUF917-domain-containing-protein	gnl\|CDD\|226065	COG3535, COG3535, Uncharacterized conserved protein [Function unknown].	0
NZ_CP022020.1\|WP_003725208.1\|520372_521476_+\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	gnl\|CDD\|237717	PRK14455, PRK14455, ribosomal RNA large subunit methyltransferase N; Provisional.	0
NZ_CP022020.1\|WP_023550313.1\|508840_510922_+\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	3.76219e-29
NZ_CP022020.1\|WP_003727318.1\|516091_516397_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|273478	TIGR01167, Zinc_metalloprotease_ZmpB, LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other].	4.34504e-05
NZ_CP022020.1\|WP_003721242.1\|499644_500592_-\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	7.47241e-102
NZ_CP022020.1\|WP_003725209.1\|521565_522045_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|226231	COG3708, COG3708, Uncharacterized protein conserved in bacteria [Function unknown].	1.03205e-42
NZ_CP022020.1\|WP_009929138.1\|498491_499640_-\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	1.37557e-52
NZ_CP022020.1\|WP_003734632.1\|495463_496219_-\|DUF4866-family-protein	gnl\|CDD\|379782	pfam16160, DUF4866, Domain of unknown function (DUF4866). This family consists of uncharacterized proteins around 250 residues in length and is mainly found in various human gut Firmicute species and abundant in human gut metagenomic datasets. The function of this family is unknown.	2.71521e-121

>NZ_CP022020.1|WP_023550313.1|508840_510922_+|BspA-family-leucine-rich-repeat-surface-protein
MKKFSMRVVLIISVLFIALGNANVSIAQERDTTNKLPEEELGSLDTSNLIAEEVAQEKPAEVENLEEIPTTDELMQNPEVREQPVADSDDPDLTAVSSGDYWTIYYNSANDEYSLRMFGNVPSSKPSAWNSYLKYIKHIEIEEATLTGDFSSYFRSNVFTVLESVRIERSNLSGVTSFARAFEGDSESESPLEKVIIRDNYYQETPSLTNISRMFTLCRKLSELDVSGLNTSSVTKMDTIFSNANSLKELDVSHFDTSSVTDMSSMFAACNSLEELDVSNFDTSSVTNMKYMLSGLHLKKLDVSNFDTSSVTNMYGMFAYCYNLEELDVSNFDTSSVNNMLHMFYVCNNLEELDLSNFDTSSVTNMFAMFAYCTSLKEIDVSNFDTSSVTTMSAMFFECSSLEALDLSNFDTSSVTTMASMFENSTALKSLYLDNFTDAASMTDMFKGTTSLTYLFVSHNLSTFNRLENTSWYDEKNWVQFSNLSQLQTYHRKQSEPTGYRKGAFLSLTMDAMGGEFEDAEEQKVQNKVSGEYWEEIVPVKEDYYFDGWYLDQNFTNKFDFSLPAAVSTTIYAKWVENYTVIIPASISLNEATELKVEGINRGSKALSVGLNRLATSVSESNELTLANTADTTVQCSAPLSWDGSENNPEKAILTLAPGSEITEGDAVMAIEAPENIQAGKYTGNLVFSINYE
>NZ_CP022020.1|WP_023550311.1|507038_508577_+|helix-turn-helix-domain-containing-protein
MREYLDSKSQKKVALLEKIFYAENHTSTQEELLNDLNITYPTLISTIKTINFDIERFGYKAFSIVHSAPNLSYTLKISDNCSIQLIINAYIRESPKFQILETLLLASFPNLQALAKKVHVSYSGIKKEIKELNEELRERNLSISTGNQVEITGDEFSLRIFYAFLFLVAYSGDRWPFSFVQYDEITDILESCPKEIYRANSIDKAMMIHYYVAMHLLRDRMNCQIDTTRQFKVALYKACTEESKKSESAFIKKVAKQLPNRNYKEMTYTTQIILSTIVAFGSYSSIEKMPSFFYMDEQLEEMGFMKLVDFASEQVNDNLSIPFSEKEMELLRYSFASINYRYFLLDNLINKFNNIVPGYTNLDRNIRKIHKVNHLEPLISQLVNLKEMDPLKPFEERLASDYLIILDKRIDFSIHTLPIKVTILSTISNETAVFDFMRYFSSYYNLEIINQVDPVVDLYISDFSVSPEVLTSLRINQPIIYVNTRWLESDYVKINDNLAKIARKKFIANKKN
>NZ_CP022020.1|WP_003728092.1|504854_506405_+|hydantoinase/oxoprolinase-family-protein
MYKIGIDVGGTNTDAVILDENQQLIHSVKMPTSEDIETGITESLHRVLSETGIDRSKVTHAMLGTTQCTNAIVERKKLAKVGVLRLGYPATASVLPYTAWPEDMVGFLSGKYKLTGGGYEYDGQVLSEINEAEIRETLASWKGEVESVAVVGVFSSLKNDQELAVQKIIEEELGADIPVSISSSVGSVGLIERENATILNAALFKVIAATSDGFEKALEQEGIAHAEIYLCQNDGTLMSLNYARQFPILTIACGPTNSIRGASYLAGLKDAMVLDVGGTTSDIGVLTDGFPRESSLAVDVGGVRTNFRMPDIISIGLGGGSIVREKDGDITIGPDSVGYRISEEALVFGGKTMTTTDIAVRLGRAEIGNPELVAHIPTDFAEKAYKKIAEMTEDAIDKMKTSSGSVSLVLVGGGSVIIPDEISGVAQIFRDKNGPVANAIGASISQISGQYEQIYIYSQIEREEALQDAEQKAREQATLAGAVTDSIEVVEVEEIPLAYHPGNATRLRVKVVGNLV
>NZ_CP022020.1|WP_003728093.1|503761_504862_+|DUF917-domain-containing-protein
MRYLDEQAIENIAIGAAFLGTGGGGDPYIGKMMALTAIKKHGPIKLLSPEEIADDDYFIPAAMMGAPSVLIEKFPKGDEFVRVFEKLGRYVGKEVKGTFPMEAGGVNSMIPIVVAAQLGLPMVDCDGMGRAFPELQMVTFHLDGISATPMAITDEKGNIGIMETIDNKWTERLARVTTVEMGASSLVSLYPCNGAQIKQSSIKNIVTLSEEIGKVIRETSMDEAEKLQKLLDVTHGYHLFEGKITDVVRETRAGFNFGRVKIDGLNKDTGSEVIVHFQNENLVAEKNGEPIAITPDLICMVDLETLMPVTTEALKYGKRVRVMALPADDAWRTDKGIETVGPRYFGYDVDFEPLEELVKKEERRHV
>NZ_CP022020.1|WP_003725189.1|502477_503761_+|cytosine-permease
MTEKKSVEQTQSWQSLAFVWTGAMICVPSLLVGGTLISGMPLWEAILIALLGYGVIVLFMIYQGMQSSDLGIPAVSVASQVFGEQGSKKIISILLAIACLGWFGIQANVCGAAFSQFLGIYGINLPVPVSSLIWGVIMLLSAIYGIRILSILNYIAVPVLLFVCIYGLVVSLNDGGLAIVENYKPAGSMSFMTGLAITIGSFALGAVIAGDYSQYTKSRKDVVKAAIVGILPSGVLMITVGAVLALTAGTADISVVFTNLGLPVLGIIGLILAAWTTNAVNAFSGGIAIINVFNISEKYHKVAVAVAGGLGTILAVIGILNHFVPIMSVLSAMVPPVAGVMIASYWIVQKGDKSKWAPVPGVNWLGVSSWLVGAVIAGIPVILTFFPELPQLPNQPLIGIILSLAVYLIGAKVLSGKTNNVENLEGK
>NZ_CP022020.1|WP_003740428.1|500747_502343_+|PucR-family-transcriptional-regulator
MSVKLADLMKLPSLKEAKVVSGKSGLSKLVSSISVLEYTEVALLEDDLFDNDEFYGSEIVVSAFVNIRDDVEAQCRTIERLHKVGEVALILYYVGIFVPKMDQKLIDFANELDFTIIVMPENEMSLRYSEVIYEVVEAIVKQEMTDTNFVTESLEQISSVRPPQRNIDTTLKILSDRTHTSLVLTDNSFQVINSITWPRTRHWDFERIIEASKQIGEHELVQLTLDERDFYTARKPIFQDGMQAMHLFMMKEKGVLTADVVMQITEVVQVFMNLWGRNYVEISTAELMKAILNDESVKMRRLGKILNVDVSSIKWMWLVKTEEIRDNEQVLAELKSFVASHFQVSLIDLFEDNIVVLLDNSVAQRDRTHTANEFAMMMKEHGIDLKITVCQGMEQTSDVQSAYSLVNEYKNAANAIYANKSIYSLQEIDFAAKCVEIVDRGELAIAEQMRPLKPLEDNDELIETLSVFLLEGESNYNQAAELLFLHKNTIKYRIQRINELLQYPATKIPESYNLYLAVAIRRILGGNNNNK
>NZ_CP022020.1|WP_003721242.1|499644_500592_-|MoxR-family-ATPase
MSIEPSIKIEEIINEVEKVIVGKRHVVKLSLTALLAGGHVLLEDVPGVGKTMMVRTLSKTIGVSFKRIQFTPDLLPADVTGVSIFNPETRDFEFRPGPVMGNIVLADEINRTAPRTQAALLEGMAENSVTVDGITRKLANPFFVMATQNPIEYEGTYALPEAQLDRFLLKINIGYPTVEEEMQLLTLKQYQDPLDQTQQVVTLSELLDLKNKAKQVFIDDVLKNYIIRLVDATRKHPSVALGISPRGSLAFMQAAQAFALIEGRDYVIPDDIQYLAPYIFTHRLILKSEAYYNEETAESIIASILKNTSVPVEKR
>NZ_CP022020.1|WP_009929138.1|498491_499640_-|DUF58-domain-containing-protein
MLKKRLLLAFRWIIMLIIYAGLWTYTLFQGDTASWFLTYFFSFILLLLFLSSIYPLKAWKVNRRFVKNTYHDGDLIDMQVSFTRKSRYPVGYLLFQQKIPASFGNVSARQQVVYPLFKKHFTVTLAGFVGVRGIHSFPPVDVETSDAFGLLERSRQLSSEKSLTIYPTYFPDVLEKISEASPENERNAAYWTLKKNSNLHSLREFSSGDRISLIDWKSSAKSDQLMTREFENSATSRLSVIFYGASHPNFELSLRAAYSFIRKISEDNGEIRVTLLGDQTSKFAPAKGTSRLQDISTAFAEIAPVDSLTLQESLDSNLHSGEKILLFTPCIDTMLMQKVTRLTDNKQLQIITFQSEHSKAMDAPAIFLEPASLLSRWEREAK
>NZ_CP022020.1|WP_003725186.1|496335_498495_-|transglutaminase
MKRYLTLVMLFILSVLLISEWIYPFAELTELSTANWIILFITLSLGSFFLRLKYYWTIPLHIVMIIFVSGIYYAKGGILAGNWFVSFFQITFNGFRDMVQFRSSDISMDFILIVFLIALWLLSYITTYSILRKQRVMSVLVLTVAYLAVINTFTDYNSNWAIVRTVLEGFLLLHLALASRIAAPNRISADSLKRNGLFYHIFVILLLAVFVFSSLMLPKKAPIFPDPVPTIKNALGINTTRTVGYSEDDTTLGGALKKDNATVFTARAEKGHYWRVESKTVYTGTGWANANSADVISFSSGDNFPIQLTEQTTGATNTAEISFASSNDYMPYPYGTQTVNGAVDSFSANLTIERVGPVDTIKNYTVQLKTPVYNIEKMQNADFSTLSNAFVSQYTQTPKDLPDRVTKLANKVTKDADSIYDKTKAIERYLSASGTFTYSTEDAKETPRGADYVDQFLFETQIGYCDNFSTSMVVMLRSLGIPARWAKGYTPGEGEKKENDAKTTYTITNNNAHSWPEVFFPGTGWVPFEPTATFSNPENFQEPTTETANKPETPNDSTSTPETPNTADKTPEQDNGSSSTGETPKKEEPKTETAASNFEIPSWVWWIPAGLVVTLLALAIIFRRRIRRYLLLRSLRNSPEFGKTYHRLMKLLASYGYVRESSETLRHFSTRVDAELTTTEFSRLTKMYEAQIYSNNLTEKVITAEETQLVQQVIARLTK
>NZ_CP022020.1|WP_003734632.1|495463_496219_-|DUF4866-family-protein
MTTIFPKEQNVAPLFEQILANPTACRRFKDVFLDNLESYQETRGFEKDDTLFAKIILSAYRQSDVSALLLGVCGRTLFELLRQAFLIPKKLTVDNPFFLTDKEGNFIAKKDDISNREQEKFQEIYQSDLHHSETTIFLVDDDDIIHSYEPDFSISTKRINKKRGILVLYSLPDTLKLGMTESEVYAFIWKTFLHIQEIIPSSRIFYGQETSENADELGVFLPIHHFEKKMLQNIEQVNELVDALREQMVNK
>NZ_CP022020.1|WP_026747116.1|513262_515020_+|BspA-family-leucine-rich-repeat-surface-protein
MKKFSMRVVLIISVLFIALGSANVSTAQERDTTNKLPEVELGSLDTSNIIAEEVAQEKPAEVEQLEEIPTTDELMQNPDVLEQPVADSDDTDLTVVSSGDFWTIYRNTVNNEYSLCMFGNVPSSRPTAWNTYLNRIKHIEIEEATLTGSFASYFSGDYFTVLESVKIEQCNLSGVTSFEKAFYNSGIEKVIIRDNDYPTAPSLLTTQYMFQLCRKLSELDLSGLDTSAITNIYGMFQFCSGLEELDLSHFDTSSVTNMYSMFSGCGSLEILDVSNWDTSSVTNMNRMFQNCTSLEELDLSTFDTSSMTDMGMMFNGCTALKSLYLDNFTDAAIMTDMFTGTTSLTYLFVSHNLSTFNNLENTSWYDEKNWVQFSNLSQLQTYHRNQSEPTGYRKGAFLSLTMDAMGGEFEDAEEQKVQNKISGEYWEEVIPVKEGHYFDGWYLDQNFTNKFDFSLPAAVSTTIYAKWVENYTVVIPASISLNEATELKVEGINRGSKTLSVGLNYGETTISENNKLTLSNTADATVQCLVPLSWDGSENNPENAILTLAPGSEITEGDAVMEIKSPENIQAGKYTGNVVFSIKYE
>NZ_CP022020.1|WP_003721252.1|515085_515559_+|hypothetical-protein
MKKKRVVIISLLLLLVSVIGISSYFLFKDKINLLDVDHSAVDWNGKKQKDTSGEENTIAIPGFEKVTLYANETKQAVNFHNPEINDCYFKISLIHPDGSVLWISDLIEPGKGMYSIELEKTLAVGEYENAVLKYECFSLNDQSPLNGSEINLKLVVV
>NZ_CP022020.1|WP_003721253.1|515578_516064_+|hypothetical-protein
MNKLVLSTLSVAAMGMVFFSGGTAYAADKEGNTVVEYSVEGDYTLVVPEKVNLSNDNATEMSVKTINRNLEPGKEVEVTLSSGLSADGEIELQRVGAISDVITSSFKSNNSVVPMANPVIGSFSGYAMEETEVSKIQIGNPQGDKKAGAYQTTLTFTAAFK
>NZ_CP022020.1|WP_003727318.1|516091_516397_+|LPXTG-cell-wall-anchor-domain-containing-protein
MKRKLVLAMVLISFCGMFFLSPDRVQASQTVVEVLISEDDLDVSEENIQEIPKKELAASSDKDNKQPILPKAGDTVTNYTLLGLVLVLIWLIMQRKRKKKE
>NZ_CP022020.1|WP_003725199.1|516472_516739_+|hypothetical-protein
MARIEYGEEIQKSLLVLYSRGSTIDSICKEYGIPRYEFHKWMKLHDADKLETKEVKTFLQIRELKQQKNKLEEEILFLNEAINLLESP
>NZ_CP022020.1|WP_003733207.1|517851_518412_+|TetR-family-transcriptional-regulator
MAESLITKKAIAGGLMELCQHKRFEKISIADITNICGLNRQTFYYHFTDKYDLLTWTYENDFFHCLADGITLGNWDKHVLKMLESIKENADFYKNTVSADASILSFCFSKLTNSLFMDLFEKIDTNGAVNEADRVFYAEFFSYGCSGVLIKWITRGFKEAPETIANQLFRLAKDTEFLANSMYREN
>NZ_CP022020.1|WP_003728986.1|518521_520222_+|oleate-hydratase
MKNKKRTLVALTGAAIGTGIAAKKISEQKAAEKERAVDEAIKARYYGDKQVYFVGGGIASLAGAVYLIRDANFDGKNIHIIEGMHILGGSNDGAGSVEHGFVCRGGRMLNEETYENFWDLFSSIPSLDMPNFSVTEEILNFDHLHPTHAQARLVDKDRNILDAHSMGFNNNDRMLMTKLLATPEEKLDNLTIRDWFDEHFFETNFWYMWQTTFAFQKWSSLFEFRRYMNRMMLEFSRIDTLEGVTRTPLNQYESLILPLKTFLDKHHVDFTINQTVEDIDFKDAPGITATALHLSDGSTIELGPDDDVIMTNACMTDSATLGDMNTPAPKPEEKPISGELWYKVAQKKPNLGNPEPFFGHEEETNWQSFTVTCHGDKLLKRIERFTGNIPGSGALMTFKDSNWLMSTVVAAQPHFKAQDANTTIFWGYGLYPDRVGDFVKKPMKECTGEEILYELMCHLNWQDDFEEIKADIINVIPCYMPYIDAQFEPRAMSDRPAVVPEGSTNFAMISQFVEIPKDMVFTEEYSVRAARIAVYTLLDIDKKICPVTPHNRDPKVLAKATQTMFR
>NZ_CP022020.1|WP_003725208.1|520372_521476_+|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN
MEKSSIYGLTWTKLTEWLEAHGQKKFRATQVWDWLYRKRVKTFEEMSNVPKETIELLTANFVMNTLEEQVVQESTDGTTKYLFKLSDGNLIETVMMKQEYGLSVCVTTQVGCNIGCTFCASGLLKKSRDLTAGEIVEQIMNVQHYLDGRNLEERVSHVVVMGIGEPFDNYDNVMDFLRVINHDKGLAIGARHITVSTSGLAPRIIDFANEDFQVNLAISLHAPNNELRTSIMRINKTYSIEKLMEAIHYYVNKTNRRITFEYIMLKGVNDHKKEALELAALLGEHRHLAYVNLIPYNPVDEHIDYERSTKEDVLAFYDTLKKNGINCVIRREHGTDIDAACGQLRSKQIKRVGVRERMKQKQAAAEE
>NZ_CP022020.1|WP_003725209.1|521565_522045_+|AraC-family-transcriptional-regulator
MEVEIVERNAFTAVGKKRTFSVENDAQKEKISQFWQEANTNGDAERINELAEFATIDGILGVCKMNGDKMDYYIAIESELTPPADMEKLIIPASKWAIFKSVGPLPSAIQKVWEYIYGEWFQTSNYAHGNAPELEVYTEGDTTAADYYSEVWIPVVEKE
>NZ_CP022020.1|WP_003721271.1|522202_522568_+|heme-oxygenase-IsdG
MIIVTNTIKVEKGAAEHVIRQFTGANGDGHPTKDIAEVEGFLGFELWHSKPEDKDYEEVVVTSKWESEEAQRNWVKSDSFKKAHGRTKDTREQREDRKGIVGNAIARFEVVHVQNPVIVEK

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Crispr_ID: NZ_CP022020_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP022020_2

513935-514192

Orphan

Consensus_repeat	Method
GATACCAGTTCCGTTACTAATATG	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP022020_2

>merge|NZ_CP022020|2|513935-514192|CRISPRCasFinder
GATACGAGTGCTATAACTAATATATATGGCATGTTTCAATTTTGCTCTGGTCTTGAAGAGTTAGATTTAAGTCATTTTGATACCAGTTCCGTTACTAATATGTATTCCATGTTTTCGGGTTGTGGATCACTGGAGATTTTGGATGTAAGCAATTGGGATACGAGTTCCGTTACTAATATGAATAGAATGTTTCAAAATTGTACTAGTCTTGAAGAGCTAGATTTAAGTACCTTTGATACCAGTTCAATGACTGACATG

>NZ_CP022020|2|1|513935-514192|CRISPRCasFinder
GATACGAGTGCTATAACTAATATA	TATGGCATGTTTCAATTTTGCTCTGGTCTTGAAGAGTTAGATTTAAGTCATTTT
GATACCAGTTCCGTTACTAATATG	TATTCCATGTTTTCGGGTTGTGGATCACTGGAGATTTTGGATGTAAGCAATTGG
GATACGAGTTCCGTTACTAATATG	AATAGAATGTTTCAAAATTGTACTAGTCTTGAAGAGCTAGATTTAAGTACCTTT
GATACCAGTTCAATGACTGACATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP022020.1\|WP_003721252.1\|515085_515559_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022020.1\|WP_003728986.1\|518521_520222_+\|oleate-hydratase	unknown	unknown	gnl\|CDD\|227060
NZ_CP022020.1\|WP_023550311.1\|507038_508577_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|368260
NZ_CP022020.1\|WP_003725186.1\|496335_498495_-\|transglutaminase	unknown	unknown	gnl\|CDD\|376628
NZ_CP022020.1\|WP_003725189.1\|502477_503761_+\|cytosine-permease	unknown	unknown	gnl\|CDD\|271377
NZ_CP022020.1\|WP_003733207.1\|517851_518412_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379534
NZ_CP022020.1\|WP_026747115.1\|511057_513127_+\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP022020.1\|WP_003728092.1\|504854_506405_+\|hydantoinase/oxoprolinase-family-protein	unknown	unknown	gnl\|CDD\|223223
NZ_CP022020.1\|WP_003728093.1\|503761_504862_+\|DUF917-domain-containing-protein	unknown	unknown	gnl\|CDD\|226065
NZ_CP022020.1\|WP_003731249.1\|522841_524605_+\|RNA-directed-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|238824
NZ_CP022020.1\|WP_003725208.1\|520372_521476_+\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	unknown	unknown	gnl\|CDD\|237717
NZ_CP022020.1\|WP_023550313.1\|508840_510922_+\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP022020.1\|WP_003727318.1\|516091_516397_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|273478
NZ_CP022020.1\|WP_003721242.1\|499644_500592_-\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NZ_CP022020.1\|WP_003725209.1\|521565_522045_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226231
NZ_CP022020.1\|WP_003721271.1\|522202_522568_+\|heme-oxygenase-IsdG	unknown	unknown	gnl\|CDD\|183970
NZ_CP022020.1\|WP_003725199.1\|516472_516739_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP022020.1\|WP_003740428.1\|500747_502343_+\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225306
NZ_CP022020.1\|WP_009929138.1\|498491_499640_-\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635
NZ_CP022020.1\|WP_003721253.1\|515578_516064_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP022020.1\|WP_003740428.1\|500747_502343_+\|PucR-family-transcriptional-regulator	gnl\|CDD\|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	2.42853e-59
NZ_CP022020.1\|WP_003728986.1\|518521_520222_+\|oleate-hydratase	gnl\|CDD\|227060	COG4716, COG4716, Myosin-crossreactive antigen [Function unknown].	0
NZ_CP022020.1\|WP_023550311.1\|507038_508577_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|368260	pfam05043, Mga, Mga helix-turn-helix domain. M regulator protein trans-acting positive regulator (Mga) is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This domain is found in the centre of the Mga proteins. This family also contains a number of bacterial RofA transcriptional regulators that seem to be largely restricted to streptococci. These proteins have been shown to regulate the expression of important bacterial adhesins. This is presumably a DNA-binding domain.	1.01429e-19
NZ_CP022020.1\|WP_003725186.1\|496335_498495_-\|transglutaminase	gnl\|CDD\|376628	pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine, and aspartate residues that form the catalytic triad in the structurally characterized transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologs of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.	4.40206e-28
NZ_CP022020.1\|WP_003725189.1\|502477_503761_+\|cytosine-permease	gnl\|CDD\|271377	cd11484, SLC-NCS1sbd_CobB-like, nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain. This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).	2.40318e-96
NZ_CP022020.1\|WP_003733207.1\|517851_518412_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|379534	pfam14278, TetR_C_8, Transcriptional regulator C-terminal region. This domain is a tetracycline repressor, domain 2, or C-terminus.	2.23521e-25
NZ_CP022020.1\|WP_026747115.1\|511057_513127_+\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	8.72154e-31
NZ_CP022020.1\|WP_003728092.1\|504854_506405_+\|hydantoinase/oxoprolinase-family-protein	gnl\|CDD\|223223	COG0145, HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	1.15698e-106
NZ_CP022020.1\|WP_003728093.1\|503761_504862_+\|DUF917-domain-containing-protein	gnl\|CDD\|226065	COG3535, COG3535, Uncharacterized conserved protein [Function unknown].	0
NZ_CP022020.1\|WP_003731249.1\|522841_524605_+\|RNA-directed-DNA-polymerase	gnl\|CDD\|238824	cd01646, RT_Bac_retron_I, RT_Bac_retron_I: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA branches out from a small ssRNA molecule via a 2'-5'phosphodiester linkage. Bacterial retron RTs produce cDNA corresponding to only a small portion of the retron genome.	1.43128e-28
NZ_CP022020.1\|WP_003725208.1\|520372_521476_+\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	gnl\|CDD\|237717	PRK14455, PRK14455, ribosomal RNA large subunit methyltransferase N; Provisional.	0
NZ_CP022020.1\|WP_023550313.1\|508840_510922_+\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	3.76219e-29
NZ_CP022020.1\|WP_003727318.1\|516091_516397_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|273478	TIGR01167, Zinc_metalloprotease_ZmpB, LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other].	4.34504e-05
NZ_CP022020.1\|WP_003721242.1\|499644_500592_-\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	7.47241e-102
NZ_CP022020.1\|WP_003725209.1\|521565_522045_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|226231	COG3708, COG3708, Uncharacterized protein conserved in bacteria [Function unknown].	1.03205e-42
NZ_CP022020.1\|WP_003721271.1\|522202_522568_+\|heme-oxygenase-IsdG	gnl\|CDD\|183970	PRK13316, PRK13316, heme oxygenase IsdG.	3.55164e-70
NZ_CP022020.1\|WP_009929138.1\|498491_499640_-\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	1.37557e-52

>NZ_CP022020.1|WP_026747115.1|511057_513127_+|BspA-family-leucine-rich-repeat-surface-protein
MKKLSIRVILIVTIIFIACGSANVSIAQERDIINKLPEVELGSLYTSNLITEEVAQDKPAEVENLEQAPTTDDLVQNPDVLEQPIADSDDSDLTVVNSGDFWTIYRNTVNGEYSLHMFGNVPSSKPTAWNSYLNRIKHIEIEEATLTGNFSSYFRNNVFTVLESVRIERSNLSRVTSFALAFYGSGIEKVIIRDNNYPTAPSLLTTEGMFKNCSNLMEVDLSGLDTSAVTTMWDMFNSCRALEELDVSNFDTSSVTNMSYMFYDNRNLEVLDVSNLDTGSVTNMYAMFEDCTSLEELDVSNFDTSSVTDMYRVFNGCEKLKKLDVSNFDTSSATAMVQMFRNCSALEKLDVSNFNTSLVTDMRAMFAGCTSLEALDVSNFDTSSVTNMAAMFSDNEKLEKLDLSTFDTSSVTNMGTMFKNCTALKSLFLDNFTHAASSTDMFTGTTSLSYLFVSHNVSNFNGLENTNWYDEKNWVQFSNLSQLQTYHRKQSEPTGYRKGEFLSLTMDAMGGQFEDAEEQKVQSKISGEYWEEVIPVKEGHYFDGWYLDQNFTNKFDFSLPATVSATLYAKWVENYTVVIPASISLNEATELKVEGINRGSKTLSVGLNYEETTISESNKLTLSNTADTTVQCLAPLSWDGSETNPKNAILTLAPGSEITEGDAVMEIESPENIQAGTYTGNLVFSINYE
>NZ_CP022020.1|WP_023550313.1|508840_510922_+|BspA-family-leucine-rich-repeat-surface-protein
MKKFSMRVVLIISVLFIALGNANVSIAQERDTTNKLPEEELGSLDTSNLIAEEVAQEKPAEVENLEEIPTTDELMQNPEVREQPVADSDDPDLTAVSSGDYWTIYYNSANDEYSLRMFGNVPSSKPSAWNSYLKYIKHIEIEEATLTGDFSSYFRSNVFTVLESVRIERSNLSGVTSFARAFEGDSESESPLEKVIIRDNYYQETPSLTNISRMFTLCRKLSELDVSGLNTSSVTKMDTIFSNANSLKELDVSHFDTSSVTDMSSMFAACNSLEELDVSNFDTSSVTNMKYMLSGLHLKKLDVSNFDTSSVTNMYGMFAYCYNLEELDVSNFDTSSVNNMLHMFYVCNNLEELDLSNFDTSSVTNMFAMFAYCTSLKEIDVSNFDTSSVTTMSAMFFECSSLEALDLSNFDTSSVTTMASMFENSTALKSLYLDNFTDAASMTDMFKGTTSLTYLFVSHNLSTFNRLENTSWYDEKNWVQFSNLSQLQTYHRKQSEPTGYRKGAFLSLTMDAMGGEFEDAEEQKVQNKVSGEYWEEIVPVKEDYYFDGWYLDQNFTNKFDFSLPAAVSTTIYAKWVENYTVIIPASISLNEATELKVEGINRGSKALSVGLNRLATSVSESNELTLANTADTTVQCSAPLSWDGSENNPEKAILTLAPGSEITEGDAVMAIEAPENIQAGKYTGNLVFSINYE
>NZ_CP022020.1|WP_023550311.1|507038_508577_+|helix-turn-helix-domain-containing-protein
MREYLDSKSQKKVALLEKIFYAENHTSTQEELLNDLNITYPTLISTIKTINFDIERFGYKAFSIVHSAPNLSYTLKISDNCSIQLIINAYIRESPKFQILETLLLASFPNLQALAKKVHVSYSGIKKEIKELNEELRERNLSISTGNQVEITGDEFSLRIFYAFLFLVAYSGDRWPFSFVQYDEITDILESCPKEIYRANSIDKAMMIHYYVAMHLLRDRMNCQIDTTRQFKVALYKACTEESKKSESAFIKKVAKQLPNRNYKEMTYTTQIILSTIVAFGSYSSIEKMPSFFYMDEQLEEMGFMKLVDFASEQVNDNLSIPFSEKEMELLRYSFASINYRYFLLDNLINKFNNIVPGYTNLDRNIRKIHKVNHLEPLISQLVNLKEMDPLKPFEERLASDYLIILDKRIDFSIHTLPIKVTILSTISNETAVFDFMRYFSSYYNLEIINQVDPVVDLYISDFSVSPEVLTSLRINQPIIYVNTRWLESDYVKINDNLAKIARKKFIANKKN
>NZ_CP022020.1|WP_003728092.1|504854_506405_+|hydantoinase/oxoprolinase-family-protein
MYKIGIDVGGTNTDAVILDENQQLIHSVKMPTSEDIETGITESLHRVLSETGIDRSKVTHAMLGTTQCTNAIVERKKLAKVGVLRLGYPATASVLPYTAWPEDMVGFLSGKYKLTGGGYEYDGQVLSEINEAEIRETLASWKGEVESVAVVGVFSSLKNDQELAVQKIIEEELGADIPVSISSSVGSVGLIERENATILNAALFKVIAATSDGFEKALEQEGIAHAEIYLCQNDGTLMSLNYARQFPILTIACGPTNSIRGASYLAGLKDAMVLDVGGTTSDIGVLTDGFPRESSLAVDVGGVRTNFRMPDIISIGLGGGSIVREKDGDITIGPDSVGYRISEEALVFGGKTMTTTDIAVRLGRAEIGNPELVAHIPTDFAEKAYKKIAEMTEDAIDKMKTSSGSVSLVLVGGGSVIIPDEISGVAQIFRDKNGPVANAIGASISQISGQYEQIYIYSQIEREEALQDAEQKAREQATLAGAVTDSIEVVEVEEIPLAYHPGNATRLRVKVVGNLV
>NZ_CP022020.1|WP_003728093.1|503761_504862_+|DUF917-domain-containing-protein
MRYLDEQAIENIAIGAAFLGTGGGGDPYIGKMMALTAIKKHGPIKLLSPEEIADDDYFIPAAMMGAPSVLIEKFPKGDEFVRVFEKLGRYVGKEVKGTFPMEAGGVNSMIPIVVAAQLGLPMVDCDGMGRAFPELQMVTFHLDGISATPMAITDEKGNIGIMETIDNKWTERLARVTTVEMGASSLVSLYPCNGAQIKQSSIKNIVTLSEEIGKVIRETSMDEAEKLQKLLDVTHGYHLFEGKITDVVRETRAGFNFGRVKIDGLNKDTGSEVIVHFQNENLVAEKNGEPIAITPDLICMVDLETLMPVTTEALKYGKRVRVMALPADDAWRTDKGIETVGPRYFGYDVDFEPLEELVKKEERRHV
>NZ_CP022020.1|WP_003725189.1|502477_503761_+|cytosine-permease
MTEKKSVEQTQSWQSLAFVWTGAMICVPSLLVGGTLISGMPLWEAILIALLGYGVIVLFMIYQGMQSSDLGIPAVSVASQVFGEQGSKKIISILLAIACLGWFGIQANVCGAAFSQFLGIYGINLPVPVSSLIWGVIMLLSAIYGIRILSILNYIAVPVLLFVCIYGLVVSLNDGGLAIVENYKPAGSMSFMTGLAITIGSFALGAVIAGDYSQYTKSRKDVVKAAIVGILPSGVLMITVGAVLALTAGTADISVVFTNLGLPVLGIIGLILAAWTTNAVNAFSGGIAIINVFNISEKYHKVAVAVAGGLGTILAVIGILNHFVPIMSVLSAMVPPVAGVMIASYWIVQKGDKSKWAPVPGVNWLGVSSWLVGAVIAGIPVILTFFPELPQLPNQPLIGIILSLAVYLIGAKVLSGKTNNVENLEGK
>NZ_CP022020.1|WP_003740428.1|500747_502343_+|PucR-family-transcriptional-regulator
MSVKLADLMKLPSLKEAKVVSGKSGLSKLVSSISVLEYTEVALLEDDLFDNDEFYGSEIVVSAFVNIRDDVEAQCRTIERLHKVGEVALILYYVGIFVPKMDQKLIDFANELDFTIIVMPENEMSLRYSEVIYEVVEAIVKQEMTDTNFVTESLEQISSVRPPQRNIDTTLKILSDRTHTSLVLTDNSFQVINSITWPRTRHWDFERIIEASKQIGEHELVQLTLDERDFYTARKPIFQDGMQAMHLFMMKEKGVLTADVVMQITEVVQVFMNLWGRNYVEISTAELMKAILNDESVKMRRLGKILNVDVSSIKWMWLVKTEEIRDNEQVLAELKSFVASHFQVSLIDLFEDNIVVLLDNSVAQRDRTHTANEFAMMMKEHGIDLKITVCQGMEQTSDVQSAYSLVNEYKNAANAIYANKSIYSLQEIDFAAKCVEIVDRGELAIAEQMRPLKPLEDNDELIETLSVFLLEGESNYNQAAELLFLHKNTIKYRIQRINELLQYPATKIPESYNLYLAVAIRRILGGNNNNK
>NZ_CP022020.1|WP_003721242.1|499644_500592_-|MoxR-family-ATPase
MSIEPSIKIEEIINEVEKVIVGKRHVVKLSLTALLAGGHVLLEDVPGVGKTMMVRTLSKTIGVSFKRIQFTPDLLPADVTGVSIFNPETRDFEFRPGPVMGNIVLADEINRTAPRTQAALLEGMAENSVTVDGITRKLANPFFVMATQNPIEYEGTYALPEAQLDRFLLKINIGYPTVEEEMQLLTLKQYQDPLDQTQQVVTLSELLDLKNKAKQVFIDDVLKNYIIRLVDATRKHPSVALGISPRGSLAFMQAAQAFALIEGRDYVIPDDIQYLAPYIFTHRLILKSEAYYNEETAESIIASILKNTSVPVEKR
>NZ_CP022020.1|WP_009929138.1|498491_499640_-|DUF58-domain-containing-protein
MLKKRLLLAFRWIIMLIIYAGLWTYTLFQGDTASWFLTYFFSFILLLLFLSSIYPLKAWKVNRRFVKNTYHDGDLIDMQVSFTRKSRYPVGYLLFQQKIPASFGNVSARQQVVYPLFKKHFTVTLAGFVGVRGIHSFPPVDVETSDAFGLLERSRQLSSEKSLTIYPTYFPDVLEKISEASPENERNAAYWTLKKNSNLHSLREFSSGDRISLIDWKSSAKSDQLMTREFENSATSRLSVIFYGASHPNFELSLRAAYSFIRKISEDNGEIRVTLLGDQTSKFAPAKGTSRLQDISTAFAEIAPVDSLTLQESLDSNLHSGEKILLFTPCIDTMLMQKVTRLTDNKQLQIITFQSEHSKAMDAPAIFLEPASLLSRWEREAK
>NZ_CP022020.1|WP_003725186.1|496335_498495_-|transglutaminase
MKRYLTLVMLFILSVLLISEWIYPFAELTELSTANWIILFITLSLGSFFLRLKYYWTIPLHIVMIIFVSGIYYAKGGILAGNWFVSFFQITFNGFRDMVQFRSSDISMDFILIVFLIALWLLSYITTYSILRKQRVMSVLVLTVAYLAVINTFTDYNSNWAIVRTVLEGFLLLHLALASRIAAPNRISADSLKRNGLFYHIFVILLLAVFVFSSLMLPKKAPIFPDPVPTIKNALGINTTRTVGYSEDDTTLGGALKKDNATVFTARAEKGHYWRVESKTVYTGTGWANANSADVISFSSGDNFPIQLTEQTTGATNTAEISFASSNDYMPYPYGTQTVNGAVDSFSANLTIERVGPVDTIKNYTVQLKTPVYNIEKMQNADFSTLSNAFVSQYTQTPKDLPDRVTKLANKVTKDADSIYDKTKAIERYLSASGTFTYSTEDAKETPRGADYVDQFLFETQIGYCDNFSTSMVVMLRSLGIPARWAKGYTPGEGEKKENDAKTTYTITNNNAHSWPEVFFPGTGWVPFEPTATFSNPENFQEPTTETANKPETPNDSTSTPETPNTADKTPEQDNGSSSTGETPKKEEPKTETAASNFEIPSWVWWIPAGLVVTLLALAIIFRRRIRRYLLLRSLRNSPEFGKTYHRLMKLLASYGYVRESSETLRHFSTRVDAELTTTEFSRLTKMYEAQIYSNNLTEKVITAEETQLVQQVIARLTK
>NZ_CP022020.1|WP_003721252.1|515085_515559_+|hypothetical-protein
MKKKRVVIISLLLLLVSVIGISSYFLFKDKINLLDVDHSAVDWNGKKQKDTSGEENTIAIPGFEKVTLYANETKQAVNFHNPEINDCYFKISLIHPDGSVLWISDLIEPGKGMYSIELEKTLAVGEYENAVLKYECFSLNDQSPLNGSEINLKLVVV
>NZ_CP022020.1|WP_003721253.1|515578_516064_+|hypothetical-protein
MNKLVLSTLSVAAMGMVFFSGGTAYAADKEGNTVVEYSVEGDYTLVVPEKVNLSNDNATEMSVKTINRNLEPGKEVEVTLSSGLSADGEIELQRVGAISDVITSSFKSNNSVVPMANPVIGSFSGYAMEETEVSKIQIGNPQGDKKAGAYQTTLTFTAAFK
>NZ_CP022020.1|WP_003727318.1|516091_516397_+|LPXTG-cell-wall-anchor-domain-containing-protein
MKRKLVLAMVLISFCGMFFLSPDRVQASQTVVEVLISEDDLDVSEENIQEIPKKELAASSDKDNKQPILPKAGDTVTNYTLLGLVLVLIWLIMQRKRKKKE
>NZ_CP022020.1|WP_003725199.1|516472_516739_+|hypothetical-protein
MARIEYGEEIQKSLLVLYSRGSTIDSICKEYGIPRYEFHKWMKLHDADKLETKEVKTFLQIRELKQQKNKLEEEILFLNEAINLLESP
>NZ_CP022020.1|WP_003733207.1|517851_518412_+|TetR-family-transcriptional-regulator
MAESLITKKAIAGGLMELCQHKRFEKISIADITNICGLNRQTFYYHFTDKYDLLTWTYENDFFHCLADGITLGNWDKHVLKMLESIKENADFYKNTVSADASILSFCFSKLTNSLFMDLFEKIDTNGAVNEADRVFYAEFFSYGCSGVLIKWITRGFKEAPETIANQLFRLAKDTEFLANSMYREN
>NZ_CP022020.1|WP_003728986.1|518521_520222_+|oleate-hydratase
MKNKKRTLVALTGAAIGTGIAAKKISEQKAAEKERAVDEAIKARYYGDKQVYFVGGGIASLAGAVYLIRDANFDGKNIHIIEGMHILGGSNDGAGSVEHGFVCRGGRMLNEETYENFWDLFSSIPSLDMPNFSVTEEILNFDHLHPTHAQARLVDKDRNILDAHSMGFNNNDRMLMTKLLATPEEKLDNLTIRDWFDEHFFETNFWYMWQTTFAFQKWSSLFEFRRYMNRMMLEFSRIDTLEGVTRTPLNQYESLILPLKTFLDKHHVDFTINQTVEDIDFKDAPGITATALHLSDGSTIELGPDDDVIMTNACMTDSATLGDMNTPAPKPEEKPISGELWYKVAQKKPNLGNPEPFFGHEEETNWQSFTVTCHGDKLLKRIERFTGNIPGSGALMTFKDSNWLMSTVVAAQPHFKAQDANTTIFWGYGLYPDRVGDFVKKPMKECTGEEILYELMCHLNWQDDFEEIKADIINVIPCYMPYIDAQFEPRAMSDRPAVVPEGSTNFAMISQFVEIPKDMVFTEEYSVRAARIAVYTLLDIDKKICPVTPHNRDPKVLAKATQTMFR
>NZ_CP022020.1|WP_003725208.1|520372_521476_+|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN
MEKSSIYGLTWTKLTEWLEAHGQKKFRATQVWDWLYRKRVKTFEEMSNVPKETIELLTANFVMNTLEEQVVQESTDGTTKYLFKLSDGNLIETVMMKQEYGLSVCVTTQVGCNIGCTFCASGLLKKSRDLTAGEIVEQIMNVQHYLDGRNLEERVSHVVVMGIGEPFDNYDNVMDFLRVINHDKGLAIGARHITVSTSGLAPRIIDFANEDFQVNLAISLHAPNNELRTSIMRINKTYSIEKLMEAIHYYVNKTNRRITFEYIMLKGVNDHKKEALELAALLGEHRHLAYVNLIPYNPVDEHIDYERSTKEDVLAFYDTLKKNGINCVIRREHGTDIDAACGQLRSKQIKRVGVRERMKQKQAAAEE
>NZ_CP022020.1|WP_003725209.1|521565_522045_+|AraC-family-transcriptional-regulator
MEVEIVERNAFTAVGKKRTFSVENDAQKEKISQFWQEANTNGDAERINELAEFATIDGILGVCKMNGDKMDYYIAIESELTPPADMEKLIIPASKWAIFKSVGPLPSAIQKVWEYIYGEWFQTSNYAHGNAPELEVYTEGDTTAADYYSEVWIPVVEKE
>NZ_CP022020.1|WP_003721271.1|522202_522568_+|heme-oxygenase-IsdG
MIIVTNTIKVEKGAAEHVIRQFTGANGDGHPTKDIAEVEGFLGFELWHSKPEDKDYEEVVVTSKWESEEAQRNWVKSDSFKKAHGRTKDTREQREDRKGIVGNAIARFEVVHVQNPVIVEK
>NZ_CP022020.1|WP_003731249.1|522841_524605_+|RNA-directed-DNA-polymerase
MRKKVDVLSMDNEKAREFFMKPSSYFSQNLPKYFNLGYLLESAESKLGKKQLKKEMYFENKVYSNFPNVNFLIQTNKTISTYRPITLLHPYIYVDYVNFLTEIKIWEELKERFQNLQEEVKEKIICSSLPFDIETSKEDDSKKEMALNFWKSIEQETIKYSLGYNYLLKLDISNFYGSIYTHTLCWAFHGENYSKEAKNSKNLQNLTGDKCDRKFQWMNYGETVGIPQGNVISDLMSELLLAYIDSELVKKIDDEIDYKIIRYRDDYRIFTKRLEDSTLVKRELVVLLQRFKLNLGESKTSQTTDIISGSLKEDKMYWIEHDPVTKLTSDKFYRSPKILMKKSLEEHKNKKYKTRVFNEFFKKHFHNRTYQATLQKHLLIIKVFSDLYPNSGQLIAALHEFEGRLLDLNYKDFRNIGTEVEVLIAILVDIIKKNPKITEIGVKLLSTLLKKINFEEFEMKYLESNNSNEVQSDFEVKLAYINSVNHKLSNSNYNDYLEIWMQRLVVKNLKESTTLSDLYIEQSKNELVKFCNSIIRGKEMIQIFNEDWLKDEHKIELSKFINLNEIDKLTDIISDDEIYLAEYNQMT

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

125857 : 132384

Listeria_phage(33.33%)

tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003728215.1\|125857_126310_-	ImmA/IrrE family metallo-endopeptidase	A0A059T7S0	Listeria_phage	4.0e-31	47.9
WP_003721740.1\|126315_126651_-	helix-turn-helix transcriptional regulator	A0A2H4JAR9	uncultured_Caudovirales_phage	4.0e-20	52.5
WP_009927883.1\|126867_127296_+	hypothetical protein	NA	NA	NA	NA
WP_003731177.1\|127307_127724_+	hypothetical protein	A8ASQ1	Listeria_phage	6.5e-20	37.9
WP_003728212.1\|128003_128393_+	DUF5072 domain-containing protein	NA	NA	NA	NA
WP_003721744.1\|128405_128918_+\|tail	phage major tail protein, TP901-1 family	A0A097PBF4	Streptococcus_pyogenes_phage	1.2e-47	62.7
WP_003721745.1\|128965_129268_+	hypothetical protein	NA	NA	NA	NA
WP_003740367.1\|129309_129714_+	hypothetical protein	NA	NA	NA	NA
WP_009928420.1\|129700_131569_+	membrane protein	A0A097PAU2	Streptococcus_pyogenes_phage	4.5e-20	45.8
WP_003734720.1\|131565_132384_+\|tail	phage tail family protein	A0A060AFE1	Staphylococcus_phage	7.2e-39	35.0

DBSCAN-SWA_2

689700 : 745080

Listeria_phage(54.84%)

terminase,tail,head,capsid,portal,holin,protease,transposase,integrase

attL 682407:682424|attR 742828:742845

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
682407:682424	attL	NA	NA	NA	NA
WP_031641925.1\|689700_690852_-\|integrase	site-specific integrase	A8ATX2	Listeria_phage	3.4e-87	46.3
WP_031641924.1\|690873_691587_-	lipoprotein	NA	NA	NA	NA
WP_031641923.1\|691641_692142_-	hypothetical protein	A0A1S7FYX8	Listeria_phage	7.1e-13	31.1
WP_031641922.1\|692142_692493_-	helix-turn-helix domain-containing protein	A0A059T669	Listeria_phage	2.3e-18	49.0
WP_031641921.1\|692646_692844_+	helix-turn-helix transcriptional regulator	A0A059T7X5	Listeria_phage	7.5e-11	52.3
WP_031641920.1\|692866_693193_+	DUF771 domain-containing protein	A0A2H4J474	uncultured_Caudovirales_phage	4.9e-15	41.5
WP_031641918.1\|694405_694762_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_012951305.1\|695172_695349_+	hypothetical protein	A8ATL8	Listeria_phage	1.7e-14	69.0
WP_031641917.1\|695362_695887_+	hypothetical protein	A0A059T5F9	Listeria_phage	2.8e-97	98.3
WP_003731842.1\|695899_696067_+	hypothetical protein	A8ASN5	Listeria_phage	9.2e-18	80.0
WP_003731843.1\|696078_696294_+	hypothetical protein	NA	NA	NA	NA
WP_031645809.1\|696372_696966_+	pentapeptide repeat-containing protein	A8ATE4	Listeria_phage	6.0e-43	88.6
WP_060595899.1\|697008_697722_+	SAM-dependent DNA methyltransferase	A8ATD5	Listeria_phage	2.7e-130	97.9
WP_088518278.1\|697732_698677_+\|integrase	site-specific integrase	A8ATD6	Listeria_phage	1.1e-176	98.1
WP_009928035.1\|698689_699370_+	hypothetical protein	A8ATD7	Listeria_phage	1.1e-120	96.5
WP_031641750.1\|699366_699576_+	hypothetical protein	NA	NA	NA	NA
WP_012951315.1\|699625_699817_+	hypothetical protein	NA	NA	NA	NA
WP_012951316.1\|699876_700395_+	hypothetical protein	NA	NA	NA	NA
WP_012951317.1\|700391_700934_+\|integrase	tyrosine-type recombinase/integrase	H0USV4	Bacillus_phage	4.3e-48	53.3
WP_012951318.1\|701215_701443_+	hypothetical protein	NA	NA	NA	NA
WP_102578311.1\|701468_701744_+	hypothetical protein	NA	NA	NA	NA
WP_049961585.1\|701740_702103_+	HNH endonuclease	A0A075M5R4	Enterococcus_phage	3.5e-14	44.1
WP_012951321.1\|702197_702725_+\|terminase	phage terminase small subunit P27 family	J7KC46	Streptococcus_phage	6.1e-31	46.7
WP_012951322.1\|702693_704445_+\|terminase	terminase large subunit	A0A2H4JCI4	uncultured_Caudovirales_phage	4.1e-156	50.7
WP_023552290.1\|704451_704652_+	DUF1056 family protein	NA	NA	NA	NA
WP_088518279.1\|704695_705889_+\|portal	phage portal protein	A0A2H4JAR2	uncultured_Caudovirales_phage	1.0e-81	42.3
WP_012951324.1\|705885_706452_+\|head,protease	HK97 family phage prohead protease	A0A1D6Z2A7	Staphylococcus_phage	1.0e-44	52.2
WP_012951325.1\|706515_707685_+\|capsid	phage major capsid protein	A0A060AI54	Enterococcus_phage	2.1e-44	38.1
WP_012951326.1\|707732_708071_+\|head,tail	phage gp6-like head-tail connector protein	A0A2H4JB77	uncultured_Caudovirales_phage	8.1e-13	37.8
WP_012951327.1\|708040_708361_+\|head	phage head closure protein	NA	NA	NA	NA
WP_012951329.1\|708721_709120_+	hypothetical protein	NA	NA	NA	NA
WP_031641752.1\|709140_709716_+\|tail	phage major tail protein	M1PRQ7	Streptococcus_phage	9.2e-33	42.9
WP_012951331.1\|709805_710153_+	hypothetical protein	NA	NA	NA	NA
WP_012951334.1\|714540_716784_+	minor structural protein GP75	A0A059T682	Listeria_phage	1.6e-56	29.4
WP_031641753.1\|716789_719081_+	phage minor structural protein	A0A059T7Y6	Listeria_phage	8.8e-135	38.2
WP_031641433.1\|719073_720135_+	hypothetical protein	A8ATW1	Listeria_phage	1.6e-94	68.6
WP_003722523.1\|720173_720539_+	hypothetical protein	Q9T1A0	Listeria_phage	7.4e-12	100.0
WP_003722522.1\|720551_720833_+\|holin	holin	A8ASL4	Listeria_phage	3.4e-41	94.6
WP_088518280.1\|720829_721678_+	peptidase M15	A0A059T7Y8	Listeria_phage	1.8e-138	93.6
WP_003724378.1\|722530_723202_+	hypothetical protein	NA	NA	NA	NA
WP_003724379.1\|723231_723417_+	hypothetical protein	NA	NA	NA	NA
WP_003724380.1\|723957_724491_+	DUF3267 domain-containing protein	NA	NA	NA	NA
WP_014929420.1\|724554_725472_+	aldo/keto reductase family oxidoreductase	NA	NA	NA	NA
WP_021496183.1\|725737_727618_+	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	8.3e-107	38.1
WP_003724383.1\|727712_728441_+	hypothetical protein	NA	NA	NA	NA
WP_003724384.1\|728580_729231_+	TalA family protein	M4SLG0	Cyanophage	1.7e-14	29.3
WP_003740476.1\|729273_731094_-	LTA synthase family protein	W6LM83	Streptococcus_phage	7.7e-49	28.7
WP_003727231.1\|731328_732720_+	amino acid permease	NA	NA	NA	NA
WP_088518281.1\|732809_733649_+	VOC family protein	NA	NA	NA	NA
WP_003721764.1\|733731_734016_-	hypothetical protein	NA	NA	NA	NA
WP_003724388.1\|734113_735064_+	magnesium transporter CorA family protein	NA	NA	NA	NA
WP_003724389.1\|735087_735729_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_003727229.1\|735771_738462_+	YhgE/Pip domain-containing protein	NA	NA	NA	NA
WP_003731019.1\|738507_739155_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_003731020.1\|739164_739701_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003740477.1\|739687_740680_-	DUF975 family protein	NA	NA	NA	NA
WP_003721771.1\|740870_741080_+	hypothetical protein	NA	NA	NA	NA
WP_003727224.1\|741147_741855_+	serine/threonine protein phosphatase	A0A249Y183	Enterococcus_phage	1.3e-20	28.2
WP_003724396.1\|741900_742464_-	DUF420 domain-containing protein	NA	NA	NA	NA
WP_003724397.1\|742583_743000_+	hypothetical protein	NA	NA	NA	NA
742828:742845	attR	NA	NA	NA	NA
WP_009928463.1\|743042_743672_+	endonuclease III domain-containing protein	NA	NA	NA	NA
WP_023550362.1\|743668_744565_-	Rgg/GadR/MutR family transcriptional regulator	NA	NA	NA	NA
WP_003724400.1\|744798_745080_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_3

1160969 : 1168392

Hokovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003730941.1\|1160969_1161353_+	glycerol-3-phosphate cytidylyltransferase	A0A1V0SGE7	Hokovirus	1.4e-16	40.7
WP_003727002.1\|1161374_1162358_+	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	2.0e-11	33.8
WP_026747136.1\|1162372_1163386_+	glycosyltransferase	A0A1V0SAH6	Catovirus	1.8e-10	31.2
WP_003721509.1\|1163594_1165085_+	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	9.5e-114	49.7
WP_088518287.1\|1165096_1165921_+	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	9.7e-68	52.2
WP_009929872.1\|1165933_1166242_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_009929871.1\|1166302_1166707_+	PTS lactose transporter subunit IIBC	NA	NA	NA	NA
WP_023550418.1\|1166835_1168392_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	6.0e-18	29.2

DBSCAN-SWA_4

1315287 : 1372124

Bacillus_virus(16.67%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003734523.1\|1315287_1316427_-\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_003723563.1\|1316506_1316902_-	helix-turn-helix transcriptional regulator	A9D9J6	Lactobacillus_prophage	1.3e-14	57.4
WP_003727524.1\|1317052_1317268_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003727523.1\|1317391_1317925_+\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_003731300.1\|1317940_1318606_+	hypothetical protein	NA	NA	NA	NA
WP_031695868.1\|1318893_1319805_+	hypothetical protein	NA	NA	NA	NA
WP_003723884.1\|1319919_1321203_+	trigger factor	NA	NA	NA	NA
WP_003723886.1\|1321387_1322647_+\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.4e-145	63.2
WP_003726393.1\|1322765_1323332_+	type I signal peptidase SipX	NA	NA	NA	NA
WP_003726394.1\|1323366_1323936_+	type I signal peptidase SipY	NA	NA	NA	NA
WP_003727520.1\|1324037_1324580_+	type I signal peptidase SipZ	NA	NA	NA	NA
WP_003726396.1\|1324589_1325453_+	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_003727519.1\|1325449_1326235_+	ribonuclease HII	G4YAY0	Emiliania_huxleyi_virus	6.7e-26	37.6
WP_003727518.1\|1326368_1327229_+	DNA-protecting protein DprA	NA	NA	NA	NA
WP_003727517.1\|1327501_1329580_+	type I DNA topoisomerase	A0A1V0SB35	Catovirus	5.4e-107	37.5
WP_003726401.1\|1329642_1330947_+\|tRNA	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	NA	NA	NA	NA
WP_023550485.1\|1331229_1332132_+	tyrosine recombinase XerC	A0A142K7N4	Mycobacterium_phage	1.8e-14	29.5
WP_031641425.1\|1332152_1332692_+\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_003727514.1\|1332705_1334115_+\|protease	ATP-dependent protease ATPase subunit HslU	W6AS21	Erwinia_phage	7.5e-44	27.8
WP_003726695.1\|1334135_1334915_+	GTP-sensing pleiotropic transcriptional regulator CodY	NA	NA	NA	NA
WP_023550487.1\|1335017_1335437_+	acyl-CoA thioesterase	NA	NA	NA	NA
WP_003724130.1\|1335459_1335771_+	hypothetical protein	NA	NA	NA	NA
WP_003726697.1\|1335773_1336646_+	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_003726698.1\|1336687_1337284_-	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_003727511.1\|1337441_1337849_+	CoA-binding protein	NA	NA	NA	NA
WP_003727510.1\|1338029_1339997_+	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	5.1e-123	42.5
WP_010958880.1\|1339993_1342453_+	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	1.1e-101	31.8
WP_003726814.1\|1342534_1343002_+	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_023550490.1\|1343629_1345438_+	class 1 internalin InlK	NA	NA	NA	NA
WP_088518289.1\|1345470_1347357_-	acetyltransferase	B5WZU0	Pseudomonas_phage	3.8e-43	32.2
WP_026747190.1\|1347569_1348268_+	glycerophosphodiester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	2.2e-12	32.4
WP_003723738.1\|1348500_1350177_+	glycerol-3-phosphate dehydrogenase/oxidase	NA	NA	NA	NA
WP_003726658.1\|1350303_1351221_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_003719566.1\|1351342_1351576_+	RNA chaperone Hfq	NA	NA	NA	NA
WP_012681271.1\|1351686_1352910_+	GTPase HflX	NA	NA	NA	NA
WP_003727505.1\|1352902_1354129_+	methionine gamma-lyase family protein	NA	NA	NA	NA
WP_003719570.1\|1354330_1354699_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_003723435.1\|1354769_1356104_+	type I glutamate--ammonia ligase	A0A1V0SJ53	Klosneuvirus	2.0e-06	26.4
WP_023550496.1\|1356247_1357543_+	arsenic transporter	A0A2H4PQU3	Staphylococcus_phage	2.2e-146	62.1
WP_003734519.1\|1357576_1358101_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_009928625.1\|1358131_1358746_-	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	9.3e-15	62.1
WP_026747189.1\|1358901_1359231_+	cell division suppressor protein YneA	NA	NA	NA	NA
WP_003727501.1\|1359324_1359552_+	DUF896 domain-containing protein	NA	NA	NA	NA
WP_009928628.1\|1359698_1361693_+	transketolase	NA	NA	NA	NA
WP_003726667.1\|1361913_1362153_+	YneF family protein	NA	NA	NA	NA
WP_003726668.1\|1362201_1362933_-	class I SAM-dependent methyltransferase	A0A1X9I6N4	Streptococcus_phage	2.3e-81	58.0
WP_003726669.1\|1362954_1363461_-	ParB-like nuclease domain-containing protein	A0A220GKT8	Streptococcus_phage	1.4e-56	66.7
WP_003731336.1\|1363470_1364775_-	DUF3440 domain-containing protein	A0A220GKF8	Streptococcus_phage	1.2e-133	52.1
WP_012681273.1\|1364764_1365970_-	helicase SNF2	L0P6E9	Lactobacillus_phage	7.0e-91	46.6
WP_003727498.1\|1365947_1366322_-	hypothetical protein	NA	NA	NA	NA
WP_003723449.1\|1366614_1367343_+	UMP kinase	NA	NA	NA	NA
WP_003723450.1\|1367342_1367900_+	ribosome recycling factor	NA	NA	NA	NA
WP_003727497.1\|1368130_1368889_+	isoprenyl transferase	R9W0U9	Flavobacterium_phage	4.4e-22	42.1
WP_003727496.1\|1368902_1369691_+	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_003726414.1\|1369705_1370848_+	1-deoxy-D-xylulose-5-phosphate reductoisomerase	NA	NA	NA	NA
WP_088518290.1\|1370861_1372124_+\|protease	RIP metalloprotease RseP	NA	NA	NA	NA

DBSCAN-SWA_5

1731858 : 1740577

Listeria_phage(100.0%)

holin,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_069002483.1\|1731858_1732224_+	hypothetical protein	A8ATJ4	Listeria_phage	9.6e-60	100.0
WP_015987340.1\|1732237_1732441_+	hypothetical protein	A8ATJ3	Listeria_phage	2.1e-32	100.0
WP_015987339.1\|1732468_1732690_+	helix-turn-helix transcriptional regulator	A8ATJ2	Listeria_phage	1.4e-34	100.0
WP_015987338.1\|1732752_1733718_-	PlyB054	A8ATJ1	Listeria_phage	1.0e-185	100.0
WP_015987337.1\|1733717_1733975_-\|holin	phage holin	A8ATJ0	Listeria_phage	2.0e-40	100.0
WP_015987336.1\|1733985_1734201_-	LysM peptidoglycan-binding domain-containing protein	A8ATI9	Listeria_phage	1.1e-28	100.0
WP_015987335.1\|1734219_1734666_-	hypothetical protein	A8ATI8	Listeria_phage	4.0e-68	100.0
WP_015987334.1\|1734641_1735088_-	hypothetical protein	A8ATI7	Listeria_phage	4.4e-75	100.0
WP_015987333.1\|1735274_1735616_-	hypothetical protein	A8ATI5	Listeria_phage	1.5e-46	100.0
WP_015987332.1\|1735621_1736350_-	hypothetical protein	A8ATI4	Listeria_phage	3.5e-138	100.0
WP_010991663.1\|1736370_1737012_-	hypothetical protein	A8ATI3	Listeria_phage	9.1e-114	100.0
WP_088518295.1\|1737001_1738153_-\|plate	baseplate J/gp47 family protein	A8ATI2	Listeria_phage	7.2e-210	99.7
WP_010991665.1\|1738145_1738508_-	DUF2634 domain-containing protein	A8ATI1	Listeria_phage	1.4e-58	100.0
WP_010991666.1\|1738504_1738843_-	hypothetical protein	A8ATI0	Listeria_phage	5.4e-57	100.0
WP_010991668.1\|1739648_1740014_-	hypothetical protein	A8ATH8	Listeria_phage	3.2e-63	100.0
WP_010991669.1\|1740013_1740577_-	LysM peptidoglycan-binding domain-containing protein	A8ATH7	Listeria_phage	9.2e-94	100.0

DBSCAN-SWA_6

1745298 : 1779118

Listeria_phage(100.0%)

terminase,head,integrase

attL 1766121:1766137|attR 1783195:1783211

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003731526.1\|1745298_1745511_-	hypothetical protein	A8ATH5	Listeria_phage	3.7e-32	100.0
WP_003731525.1\|1745473_1745830_-	hypothetical protein	A8ATH4	Listeria_phage	1.4e-60	100.0
WP_003731524.1\|1745882_1746281_-	hypothetical protein	A8ATH3	Listeria_phage	4.7e-68	100.0
WP_003731523.1\|1746297_1747293_-	DUF3383 family protein	A8ATH2	Listeria_phage	1.9e-182	100.0
WP_003731522.1\|1747297_1747786_-	hypothetical protein	A8ATH1	Listeria_phage	3.2e-87	100.0
WP_003731521.1\|1747775_1748150_-	hypothetical protein	A8ATH0	Listeria_phage	4.6e-65	100.0
WP_003731520.1\|1748149_1748749_-	hypothetical protein	A8ATG9	Listeria_phage	2.6e-110	100.0
WP_003731519.1\|1748748_1749084_-	DUF4054 domain-containing protein	A8ATG8	Listeria_phage	2.1e-53	100.0
WP_003731518.1\|1749095_1749482_-	hypothetical protein	A8ATG7	Listeria_phage	1.0e-64	97.7
WP_003731517.1\|1749504_1750410_-	DUF2184 domain-containing protein	A8ATG6	Listeria_phage	2.1e-164	99.0
WP_003731516.1\|1750430_1750880_-	hypothetical protein	A8ATG5	Listeria_phage	9.0e-76	100.0
WP_003731515.1\|1750879_1751989_-	DUF2213 domain-containing protein	A8ATG4	Listeria_phage	6.5e-176	100.0
WP_003731514.1\|1752037_1752208_-	hypothetical protein	A8ATG3	Listeria_phage	1.1e-26	100.0
WP_003731513.1\|1752204_1753614_-\|head	phage head morphogenesis protein	A8ATG2	Listeria_phage	7.8e-267	100.0
WP_003731512.1\|1753606_1754992_-	DUF1073 domain-containing protein	A8ATG1	Listeria_phage	1.1e-265	100.0
WP_003731511.1\|1755005_1756466_-\|terminase	phage terminase large subunit	A8ATG0	Listeria_phage	4.4e-289	100.0
WP_003731510.1\|1756443_1757328_-	hypothetical protein	A8ATF9	Listeria_phage	6.6e-139	99.3
WP_010990878.1\|1757373_1757598_-	hypothetical protein	A8ATN8	Listeria_phage	2.7e-36	100.0
WP_010991671.1\|1757625_1757856_-	hypothetical protein	A8ATN7	Listeria_phage	9.7e-34	100.0
WP_003731507.1\|1757986_1758184_-	hypothetical protein	A8ATN6	Listeria_phage	5.2e-28	100.0
WP_015987349.1\|1758231_1759569_-	ParB N-terminal domain-containing protein	A8ATN5	Listeria_phage	9.7e-259	100.0
WP_003731505.1\|1759565_1759859_-	hypothetical protein	A8ATN4	Listeria_phage	2.3e-48	100.0
WP_003731503.1\|1760386_1761154_-	hypothetical protein	A8ATN0	Listeria_phage	1.6e-141	100.0
WP_003731502.1\|1761166_1761589_-	hypothetical protein	A8ATM9	Listeria_phage	6.3e-71	100.0
WP_088518296.1\|1761669_1762230_-	hypothetical protein	A8ATM8	Listeria_phage	5.4e-102	96.2
WP_003731500.1\|1762241_1762493_-	DUF3850 domain-containing protein	A8ATM7	Listeria_phage	9.9e-40	95.2
WP_003731499.1\|1762489_1762642_-	hypothetical protein	A8ATM6	Listeria_phage	8.1e-21	100.0
WP_003731498.1\|1762842_1763178_-	hypothetical protein	A8ATZ5	Listeria_phage	4.6e-08	93.1
WP_003731496.1\|1763385_1763769_-	preprotein translocase subunit YajC	A8ATZ3	Listeria_phage	2.4e-53	88.2
WP_003731495.1\|1763872_1764088_-	hypothetical protein	NA	NA	NA	NA
WP_003731494.1\|1764084_1764294_-	hypothetical protein	A8ATE0	Listeria_phage	4.8e-32	98.6
WP_003731493.1\|1764290_1764815_-	hypothetical protein	A8ASP1	Listeria_phage	1.1e-32	47.8
1766121:1766137	attL	NA	NA	NA	NA
WP_003731491.1\|1766188_1766611_-	hypothetical protein	A8ATL9	Listeria_phage	1.2e-53	100.0
WP_003731490.1\|1766622_1766799_-	hypothetical protein	A8ATL8	Listeria_phage	2.0e-23	100.0
WP_003731489.1\|1766758_1767139_-	hypothetical protein	A8ATL7	Listeria_phage	3.1e-69	100.0
WP_003731488.1\|1767179_1767800_-	hypothetical protein	A8ATL6	Listeria_phage	1.1e-108	100.0
WP_003731487.1\|1767820_1768258_-	RusA family crossover junction endodeoxyribonuclease	A8ATL5	Listeria_phage	1.6e-77	100.0
WP_003731486.1\|1768238_1768448_-	hypothetical protein	A8ATL4	Listeria_phage	8.2e-32	100.0
WP_003731485.1\|1768448_1768655_-	hypothetical protein	A8ATL3	Listeria_phage	5.6e-33	100.0
WP_003731483.1\|1768832_1769648_-	ATP-binding protein	A8ATL1	Listeria_phage	4.8e-144	100.0
WP_003731482.1\|1769571_1770489_-	DUF4373 domain-containing protein	A8ATL0	Listeria_phage	2.2e-169	100.0
WP_003731481.1\|1770500_1771238_-	MBL fold metallo-hydrolase	A8ATK9	Listeria_phage	1.7e-135	100.0
WP_003731480.1\|1771197_1771983_-	phage recombination protein Bet	A8ATK8	Listeria_phage	7.9e-144	100.0
WP_015987342.1\|1771983_1773927_-	AAA family ATPase	A8ATK7	Listeria_phage	0.0e+00	100.0
WP_003731478.1\|1773913_1774255_-	hypothetical protein	A8ATK6	Listeria_phage	1.2e-56	100.0
WP_003731477.1\|1774272_1774500_-	hypothetical protein	A8ATK5	Listeria_phage	1.8e-32	100.0
WP_003731476.1\|1774677_1774968_-	hypothetical protein	A8ATK4	Listeria_phage	4.6e-49	100.0
WP_049872582.1\|1775117_1775312_-	hypothetical protein	A8ATK3	Listeria_phage	9.4e-22	100.0
WP_003731474.1\|1775286_1775580_-	helix-turn-helix domain-containing protein	A8ATK2	Listeria_phage	2.3e-48	100.0
WP_003731473.1\|1775594_1776119_-	hypothetical protein	A8ATK1	Listeria_phage	5.5e-93	100.0
WP_003731472.1\|1776195_1776381_-	helix-turn-helix transcriptional regulator	A8ATK0	Listeria_phage	1.2e-29	100.0
WP_003731471.1\|1776541_1776970_+	helix-turn-helix transcriptional regulator	A8ATJ9	Listeria_phage	4.0e-73	100.0
WP_003731470.1\|1776986_1777406_+	ImmA/IrrE family metallo-endopeptidase	A8ATJ8	Listeria_phage	4.0e-78	100.0
WP_003731469.1\|1777453_1777846_+	hypothetical protein	A8ATJ7	Listeria_phage	2.3e-59	100.0
WP_003731468.1\|1777942_1779118_+\|integrase	site-specific integrase	A8ATJ6	Listeria_phage	6.2e-225	100.0
1783195:1783211	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1852200 : 1885065

Erysipelothrix_phage(70.0%)

terminase,tail,head,capsid,portal,holin,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014929970.1\|1852200_1853115_-	N-acetylmuramoyl-L-alanine amidase	A0A1D8ETE4	Propionibacterium_phage	3.9e-33	44.0
WP_025186379.1\|1853104_1853518_-\|holin	phage holin family protein	A0A2K5B2A2	Erysipelothrix_phage	1.5e-37	57.0
WP_003731143.1\|1853566_1853986_-	DUF1617 family protein	A0A1S5RCP5	Lactobacillus_phage	2.4e-06	26.5
WP_003731142.1\|1853972_1854134_-	hypothetical protein	NA	NA	NA	NA
WP_003731141.1\|1854146_1858211_-	hypothetical protein	A0A1B1P770	Bacillus_phage	8.7e-85	41.8
WP_003731140.1\|1858195_1858888_-	hypothetical protein	A0A1L2BYA2	Clostridium_phage	1.7e-20	29.0
WP_003731139.1\|1858903_1861465_-	hypothetical protein	A0A2K5B297	Erysipelothrix_phage	3.9e-83	74.1
WP_003731138.1\|1861532_1862177_-	DUF1643 domain-containing protein	NA	NA	NA	NA
WP_003731137.1\|1862428_1862812_-	hypothetical protein	A0A2K5B295	Erysipelothrix_phage	5.4e-37	64.2
WP_003731136.1\|1862821_1863412_-\|tail	phage tail protein	A0A2K5B294	Erysipelothrix_phage	4.1e-76	72.2
WP_029645088.1\|1863413_1863722_-	hypothetical protein	NA	NA	NA	NA
WP_003731135.1\|1863748_1864180_-	HK97 gp10 family phage protein	A0A2K5B292	Erysipelothrix_phage	7.6e-40	59.4
WP_003731134.1\|1864172_1864511_-\|head,tail	head-tail adaptor protein	A0A2K5B291	Erysipelothrix_phage	1.7e-23	54.7
WP_003731133.1\|1864507_1864819_-\|head,tail	phage gp6-like head-tail connector protein	A0A2K5B290	Erysipelothrix_phage	2.2e-36	74.0
WP_003731132.1\|1864829_1866047_-\|capsid	phage major capsid protein	A0A2I4R671	Erysipelothrix_phage	1.1e-102	48.0
WP_095591263.1\|1866050_1866803_-\|protease	Clp protease ClpP	M1PLE5	Streptococcus_phage	1.9e-62	55.7
WP_014929974.1\|1866699_1868061_-\|portal	phage portal protein	A0A2K5B287	Erysipelothrix_phage	2.7e-179	74.0
WP_100066221.1\|1868128_1868389_-	hypothetical protein	NA	NA	NA	NA
WP_088518322.1\|1868520_1870113_-\|terminase	terminase large subunit	A0A2K5B285	Erysipelothrix_phage	7.2e-269	84.8
WP_003731127.1\|1870173_1870398_-	hypothetical protein	A0A2K5B284	Erysipelothrix_phage	2.0e-15	48.6
WP_023559365.1\|1870387_1870576_-	DUF5049 domain-containing protein	NA	NA	NA	NA
WP_003731125.1\|1870559_1870754_-	hypothetical protein	NA	NA	NA	NA
WP_003731124.1\|1870756_1871146_-	DUF4314 domain-containing protein	E4ZFL7	Streptococcus_phage	3.1e-16	71.0
WP_003731123.1\|1871234_1872485_-	site-specific DNA-methyltransferase	A0A2I4R670	Erysipelothrix_phage	7.4e-144	62.0
WP_100066220.1\|1872474_1872852_-	hypothetical protein	A0A0B5HE03	Vibrio_phage	4.5e-12	38.8
WP_014929977.1\|1873076_1873859_-	S-adenosylmethionine synthetase	NA	NA	NA	NA
WP_031641527.1\|1873863_1874442_-\|terminase	terminase	A0A2K5B277	Erysipelothrix_phage	1.2e-53	52.8
WP_031641526.1\|1874574_1874940_-	HNH endonuclease	A0A2K5B276	Erysipelothrix_phage	1.4e-31	56.9
WP_003731117.1\|1875107_1875536_-	DUF1492 domain-containing protein	A0A2K5B275	Erysipelothrix_phage	1.5e-27	45.8
WP_014929979.1\|1875532_1876885_-	DEAD/DEAH box helicase	A0A2K5B273	Erysipelothrix_phage	6.8e-159	69.0
WP_003731115.1\|1876884_1877169_-	VRR-NUC domain-containing protein	A0A2K5B272	Erysipelothrix_phage	3.5e-25	60.2
WP_003731114.1\|1877165_1877375_-	hypothetical protein	NA	NA	NA	NA
WP_003731113.1\|1877512_1879756_-	hypothetical protein	A0A1B0RXC5	Streptococcus_phage	4.8e-210	49.7
WP_014929980.1\|1879748_1880093_-	hypothetical protein	A0A2K5B270	Erysipelothrix_phage	4.1e-28	51.4
WP_003731110.1\|1881065_1883003_-	DNA polymerase	A0A2K5B2B0	Erysipelothrix_phage	7.7e-265	68.6
WP_003731109.1\|1883063_1883606_-	DUF2815 family protein	A0A2K5B2A9	Erysipelothrix_phage	8.9e-78	77.2
WP_003731108.1\|1883607_1884750_-	DUF2800 domain-containing protein	M1Q218	Streptococcus_phage	1.5e-122	57.8
WP_010821424.1\|1884750_1885065_-	hypothetical protein	A0A2K5B2A7	Erysipelothrix_phage	6.6e-09	41.5

DBSCAN-SWA_8

1966142 : 1974428

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003726209.1\|1966142_1966709_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	8.3e-26	36.4
WP_003726210.1\|1966705_1967755_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.2e-63	44.4
WP_003722245.1\|1967773_1969201_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.1e-53	34.6
WP_009918191.1\|1969185_1971405_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	6.5e-159	40.8
WP_003726212.1\|1971397_1972081_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_003722248.1\|1972084_1972330_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_003726214.1\|1972341_1973055_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3F9V5	Synechococcus_phage	2.0e-40	38.3
WP_003729814.1\|1973135_1974428_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	2.5e-17	33.0

DBSCAN-SWA_9

2501597 : 2543154

Listeria_phage(93.75%)

terminase,tail,capsid,portal,holin,plate,integrase

attL 2498694:2498709|attR 2535753:2535768

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2498694:2498709	attL	NA	NA	NA	NA
WP_012951563.1\|2501597_2501831_-	hypothetical protein	A8ATC5	Listeria_phage	1.6e-36	98.7
WP_023548524.1\|2502227_2502395_-	hypothetical protein	NA	NA	NA	NA
WP_031641270.1\|2502659_2503505_-	peptidase M15	A0A059T7Y8	Listeria_phage	1.6e-137	94.7
WP_003722522.1\|2503504_2503786_-\|holin	holin	A8ASL4	Listeria_phage	3.4e-41	94.6
WP_003727799.1\|2503798_2504164_-	hypothetical protein	A8ASL3	Listeria_phage	1.7e-11	97.9
WP_003722524.1\|2504191_2504350_-	hypothetical protein	Q9T1A1	Listeria_phage	6.0e-19	100.0
WP_003731746.1\|2504354_2504672_-	hypothetical protein	Q9T1A2	Listeria_phage	1.7e-49	92.4
WP_088518304.1\|2504683_2505757_-\|plate	phage baseplate upper protein	Q9T1A3	Listeria_phage	1.1e-180	90.5
WP_014931687.1\|2505756_2506785_-	hypothetical protein	Q9T1A4	Listeria_phage	2.1e-189	98.8
WP_031645706.1\|2506785_2507811_-	phage minor structural protein	Q9T1A5	Listeria_phage	3.9e-191	93.3
WP_031645707.1\|2507819_2508638_-\|tail	phage tail family protein	Q9T1A6	Listeria_phage	3.8e-149	93.4
WP_088518305.1\|2508639_2514024_-	tape measure protein	Q9T1A7	Listeria_phage	0.0e+00	97.8
WP_003722531.1\|2514034_2514640_-	hypothetical protein	Q9T1A8	Listeria_phage	1.3e-109	100.0
WP_003727791.1\|2514645_2515068_-\|tail	phage tail assembly chaperone	Q9T1A9	Listeria_phage	4.1e-70	100.0
WP_003727790.1\|2515122_2515455_-	hypothetical protein	Q9T1B0	Listeria_phage	1.8e-49	99.1
WP_009925981.1\|2515384_2515819_-\|tail	tail protein	Q9T1B1	Listeria_phage	3.0e-76	97.9
WP_003737937.1\|2515821_2516229_-	hypothetical protein	A8ASK1	Listeria_phage	2.0e-66	99.3
WP_029508830.1\|2516228_2516567_-	hypothetical protein	A0A0B5CTV8	Listeria_phage	5.4e-57	95.5
WP_055310957.1\|2516566_2516929_-	hypothetical protein	A0A059T658	Listeria_phage	1.5e-60	95.0
WP_009925044.1\|2516928_2517324_-	hypothetical protein	A0A059T5E3	Listeria_phage	2.2e-54	82.4
WP_009925045.1\|2517325_2517484_-	hypothetical protein	A8ASJ7	Listeria_phage	9.6e-17	92.3
WP_088518306.1\|2517483_2518383_-\|capsid	phage major capsid protein	Q9T1B7	Listeria_phage	5.0e-166	99.3
WP_009925047.1\|2518406_2518976_-	scaffold protein	A0A0B5CTV7	Listeria_phage	1.2e-80	97.9
WP_039381673.1\|2519054_2520194_-	hypothetical protein	A8ASJ4	Listeria_phage	1.3e-200	96.0
WP_060577779.1\|2520194_2521964_-\|portal	phage portal protein	A8ASJ3	Listeria_phage	7.8e-264	91.2
WP_031645718.1\|2521976_2523308_-\|terminase	PBSX family phage terminase large subunit	A8ASJ2	Listeria_phage	3.5e-261	98.9
WP_031645719.1\|2523276_2523819_-\|terminase	terminase small subunit	A8ASJ1	Listeria_phage	1.2e-90	98.3
WP_010990212.1\|2523876_2524140_-	hypothetical protein	A0A0S2MYE7	Enterococcus_phage	1.7e-34	78.2
WP_009911405.1\|2524166_2524466_-	phage protein	A0A2H4JBC0	uncultured_Caudovirales_phage	3.8e-14	40.7
WP_003735131.1\|2524860_2525295_-	hypothetical protein	A8ASQ1	Listeria_phage	4.3e-75	99.3
WP_046377523.1\|2525439_2525844_-	endodeoxyribonuclease	A8AU00	Listeria_phage	2.1e-71	99.3
WP_014601286.1\|2525809_2525950_-	BH0509 family protein	A8ATZ9	Listeria_phage	2.6e-18	100.0
WP_088518307.1\|2525946_2526252_-	response regulator	A8ATZ8	Listeria_phage	3.4e-42	92.1
WP_088518308.1\|2526283_2526766_-	single-stranded DNA-binding protein	A8ATZ7	Listeria_phage	1.0e-77	92.5
WP_088518309.1\|2526762_2527008_-	DUF3850 domain-containing protein	A0A059T7N3	Listeria_phage	1.5e-32	90.7
WP_088518310.1\|2527000_2527336_-	hypothetical protein	A8ATZ5	Listeria_phage	2.1e-08	89.7
WP_085400849.1\|2527335_2527524_-	hypothetical protein	NA	NA	NA	NA
WP_003727764.1\|2527520_2527706_-	hypothetical protein	A0A059T5G1	Listeria_phage	4.1e-27	100.0
WP_003725081.1\|2527702_2527891_-	SAM--benzoic acid carboxyl methyltransferase	D7RWG4	Brochothrix_phage	4.4e-08	49.1
WP_088518311.1\|2527894_2528413_-	hypothetical protein	A8ASP1	Listeria_phage	9.8e-34	52.6
WP_023548475.1\|2528409_2528778_-	hypothetical protein	Q8W5X1	Listeria_phage	1.1e-55	87.7
WP_023548473.1\|2528774_2528954_-	hypothetical protein	A0A059T5G0	Listeria_phage	6.0e-23	93.2
WP_023548471.1\|2528950_2529631_-	hypothetical protein	A8ATD7	Listeria_phage	3.3e-122	97.8
WP_023548469.1\|2529643_2530588_-\|integrase	site-specific integrase	A8ATD6	Listeria_phage	1.7e-177	98.4
WP_023548467.1\|2530598_2531312_-	SAM-dependent DNA methyltransferase	A8ATD5	Listeria_phage	7.2e-128	96.6
WP_088518312.1\|2531308_2532241_-	DnaD domain-containing protein	A8ATY7	Listeria_phage	9.7e-165	98.1
WP_079441179.1\|2532260_2533076_-	recombinase RecT	A8ATY6	Listeria_phage	1.0e-149	98.5
WP_077915324.1\|2533078_2534038_-	YqaJ viral recombinase family protein	A8ATY5	Listeria_phage	2.7e-178	99.4
WP_003733629.1\|2534273_2534462_-	hypothetical protein	Q9T175	Listeria_phage	1.2e-21	80.6
WP_003733630.1\|2534569_2534785_-	hypothetical protein	Q9T176	Listeria_phage	9.7e-20	67.6
WP_003733631.1\|2534781_2535315_-	hypothetical protein	Q9T177	Listeria_phage	5.5e-80	87.6
WP_088518313.1\|2535437_2536217_-	phage antirepressor Ant	A0A059T6E7	Listeria_phage	3.4e-139	96.5
2535753:2535768	attR	NA	NA	NA	NA
WP_088518314.1\|2536280_2536511_+	hypothetical protein	A0A059T7Q3	Listeria_phage	2.0e-34	97.4
WP_003727748.1\|2536515_2536677_-	hypothetical protein	A0A059T7X7	Listeria_phage	1.2e-19	98.1
WP_003769995.1\|2536708_2536990_-	hypothetical protein	Q9T180	Listeria_phage	1.4e-39	96.8
WP_003733634.1\|2536986_2537223_-	hypothetical protein	A0A059T5E9	Listeria_phage	3.3e-37	100.0
WP_003769996.1\|2537262_2537547_-	hypothetical protein	A0A0B5D168	Listeria_phage	1.6e-46	98.9
WP_003735007.1\|2537558_2537753_-	hypothetical protein	A0A059T6E5	Listeria_phage	1.3e-26	100.0
WP_003731220.1\|2537756_2538008_-	helix-turn-helix transcriptional regulator	A8ATX6	Listeria_phage	7.6e-40	100.0
WP_009911345.1\|2538156_2538465_+	helix-turn-helix transcriptional regulator	A8ATX5	Listeria_phage	7.8e-47	98.0
WP_009911346.1\|2538495_2538987_+	bacteriophage gp35-type protein	A8ATX4	Listeria_phage	1.1e-90	98.8
WP_025370648.1\|2539009_2539228_+	zinc-ribbon domain-containing protein	A0A059T6E3	Listeria_phage	1.3e-32	97.2
WP_003770013.1\|2539243_2539966_+	hypothetical protein	A0A059T7P9	Listeria_phage	7.4e-88	84.6
WP_003770015.1\|2539987_2540863_+	hypothetical protein	A0A0B5D0D1	Listeria_phage	2.2e-150	94.5
WP_009911646.1\|2540926_2542285_+	recombinase family protein	Q8LTD8	Listeria_phage	2.0e-251	97.1
WP_031641942.1\|2542275_2542752_+	competence protein ComK	NA	NA	NA	NA
WP_003739618.1\|2542806_2543154_-	helix-turn-helix transcriptional regulator	A0A0A7RTK4	Clostridium_phage	9.9e-06	40.7

DBSCAN-SWA_10

2687473 : 2695315

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003725407.1\|2687473_2688445_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	5.2e-52	39.4
WP_003731212.1\|2688452_2689421_-	YvcK family protein	A1IMD5	Streptococcus_phage	1.8e-68	43.6
WP_003722606.1\|2689422_2690298_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.9e-08	29.7
WP_003725409.1\|2690405_2692136_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	9.5e-174	53.1
WP_077915067.1\|2692177_2693239_-	galactose mutarotase	NA	NA	NA	NA
WP_009918601.1\|2693255_2694239_-	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	3.1e-52	38.7
WP_003722610.1\|2694355_2695315_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.0e-88	53.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP022021

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP022020

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection