CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP021983	Halomicronema hongdechloris C2206 genome	28 crisprs	cas2,cas1,PD-DExK,cmr6gr7,cmr5gr11,cmr4gr7,cmr3gr5,cas10,RT,DinG,DEDDh,WYL,csa3,cas6,cas3,cas8b3,cas7,csx1,cas10d,csc2gr7,csc1gr5,cas4	7	14	3	0

1. NZ_CP021983

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP021983_1

• CRISPR_ID: NZ_CP021983_1
• CRISPR_location: 397394-397479
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP021983_1

Consensus_repeat	Method
GTCATTTTTACCCGGTCCTTGTC	CRISPRCasFinder

spacers of NZ_CP021983_1

>1.1|397417|40|NZ_CP021983|CRISPRCasFinder
CATAGCTGGGCGGGACCCATAGATTTCTCTCTGGGACGCA

CRISPR arrays and Neighbor proteins around NZ_CP021983_1

CRISPR arrays

The CRISPR arrays of NZ_CP021983_1

>merge|NZ_CP021983|1|397394-397479|CRISPRCasFinder
GTCATTTTTACCCGGTCCTTGTCCATAGCTGGGCGGGACCCATAGATTTCTCTCTGGGACGCAGTCATTTTTGCCCGGTCCTTGTC

>NZ_CP021983|1|1|397394-397479|CRISPRCasFinder
GTCATTTTTACCCGGTCCTTGTC	CATAGCTGGGCGGGACCCATAGATTTCTCTCTGGGACGCA
GTCATTTTTGCCCGGTCCTTGTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_088428923.1|391248_392079_-|multidrug-ABC-transporter-permease	unknown	unknown	gnl|CDD|226953
NZ_CP021983.1|WP_088428921.1|388073_389618_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223717
NZ_CP021983.1|WP_080812863.1|394129_394447_-|Mo-dependent-nitrogenase	unknown	unknown	gnl|CDD|369150
NZ_CP021983.1|WP_080812848.1|405647_406319_+|ribonuclease-III	unknown	unknown	gnl|CDD|234633
NZ_CP021983.1|WP_088428929.1|407427_407709_+|HNH-endonuclease	unknown	unknown	gnl|CDD|366837
NZ_CP021983.1|WP_080812856.1|397894_398458_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl|CDD|227303
NZ_CP021983.1|WP_080812860.1|395116_397105_-|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	unknown	unknown	gnl|CDD|273520
NZ_CP021983.1|WP_080812858.1|397648_397882_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088428927.1|402593_403709_+|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl|CDD|366370
NZ_CP021983.1|WP_088428919.1|386957_387518_-|peroxiredoxin	unknown	unknown	gnl|CDD|239315
NZ_CP021983.1|WP_088431481.1|392209_393211_+|DNA-ligase-associated-DEXH-box-helicase	unknown	unknown	gnl|CDD|274995
NZ_CP021983.1|WP_080812874.1|387600_387840_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088428925.1|400179_401931_-|Rieske-(2Fe-2S)-protein	unknown	unknown	gnl|CDD|239604
NZ_CP021983.1|WP_080812872.1|389619_390450_+|hypothetical-protein	unknown	unknown	gnl|CDD|225464
NZ_CP021983.1|WP_080812866.1|393600_393981_+|DUF1622-domain-containing-protein	unknown	unknown	gnl|CDD|377914
NZ_CP021983.1|WP_080812922.1|390466_391249_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|226218
NZ_CP021983.1|WP_080812854.1|399137_400121_+|ABC-transporter	unknown	unknown	gnl|CDD|226952
NZ_CP021983.1|WP_080812845.1|406385_406673_-|hypothetical-protein	unknown	unknown	gnl|CDD|226983
NZ_CP021983.1|WP_080812837.1|407762_408413_+|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NZ_CP021983.1|WP_080812841.1|407068_407431_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_088428923.1|391248_392079_-|multidrug-ABC-transporter-permease	gnl|CDD|226953	COG4587, COG4587, ABC-type uncharacterized transport system, permease component [General function prediction only].	6.57158e-76
NZ_CP021983.1|WP_080812856.1|397894_398458_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl|CDD|227303	COG4968, PilE, Tfp pilus assembly protein PilE [Cell motility and secretion / Intracellular trafficking and secretion].	5.47178e-17
NZ_CP021983.1|WP_080812863.1|394129_394447_-|Mo-dependent-nitrogenase	gnl|CDD|369150	pfam06967, Mo-nitro_C, Mo-dependent nitrogenase C-terminus. This family represents the C-terminus (approximately 80 residues) of a number of bacterial Mo-dependent nitrogenases. These are involved in nitrogen fixation in cyanobacteria. Note that many family members are hypothetical proteins.	3.09473e-52
NZ_CP021983.1|WP_088428929.1|407427_407709_+|HNH-endonuclease	gnl|CDD|366837	pfam01844, HNH, HNH endonuclease. His-Asn-His (HNH) proteins are a very common family of small nucleic acid-binding proteins that are generally associated with endonuclease activity.	5.42675e-08
NZ_CP021983.1|WP_088428921.1|388073_389618_+|FAD-dependent-oxidoreductase	gnl|CDD|223717	COG0644, FixC, Dehydrogenases (flavoproteins) [Energy production and conversion].	6.36927e-06
NZ_CP021983.1|WP_080812860.1|395116_397105_-|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	gnl|CDD|273520	TIGR01241, ATP-dependent_zinc_metalloprotease_FtsH, ATP-dependent metalloprotease FtsH. HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_CP021983.1|WP_088428927.1|402593_403709_+|mechanosensitive-ion-channel-family-protein	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	1.2396e-52
NZ_CP021983.1|WP_088428919.1|386957_387518_-|peroxiredoxin	gnl|CDD|239315	cd03017, PRX_BCP, Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing and detoxifying hydroperoxides. The protein was named BCP based on its electrophoretic mobility before its function was known. BCP shows substrate selectivity toward fatty acid hydroperoxides rather than hydrogen peroxide or alkyl hydroperoxides. BCP contains the peroxidatic cysteine but appears not to possess a resolving cysteine (some sequences, not all, contain a second cysteine but its role is still unknown). Unlike other PRXs, BCP exists as a monomer. The plant homolog of BCP is PRX Q, which is expressed only in leaves and is cellularly localized in the chloroplasts and the guard cells of stomata. Also included in this subfamily is the fungal nuclear protein, Dot5p (for disrupter of telomere silencing protein 5), which functions as an alkyl-hydroperoxide reductase during post-diauxic growth.	3.89936e-66
NZ_CP021983.1|WP_088431481.1|392209_393211_+|DNA-ligase-associated-DEXH-box-helicase	gnl|CDD|274995	TIGR04122, hypothetical_protein, putative exonuclease, DNA ligase-associated. Members of this protein family frequently are found annotated as a putative exonuclease involved in mRNA processing. This protein is found, exclusively in bacteria, associated with three other proteins: an ATP-dependent DNA ligase, a helicase, and putative phosphoesterase.	0
NZ_CP021983.1|WP_080812848.1|405647_406319_+|ribonuclease-III	gnl|CDD|234633	PRK00102, rnc, ribonuclease III; Reviewed.	3.07013e-92
NZ_CP021983.1|WP_088428925.1|400179_401931_-|Rieske-(2Fe-2S)-protein	gnl|CDD|239604	cd03528, Rieske_RO_ferredoxin, Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable microorganisms to tolerate and even exclusively utilize aromatic compounds for growth. ROs consist of two or three components: reductase, oxygenase, and ferredoxin (in some cases) components. The ferredoxin component contains either a plant-type or Rieske-type [2Fe-2S] cluster. The Rieske ferredoxin component in this family carries an electron from the RO reductase component to the terminal RO oxygenase component. BPDO degrades biphenyls and polychlorinated biphenyls. BPDO ferredoxin (BphF) has structural features consistent with a minimal and perhaps archetypical Rieske protein in that the insertions that give other Rieske proteins unique structural features are missing. CARDO catalyzes dihydroxylation at the C1 and C9a positions of carbazole. Rieske ferredoxins are found as subunits of membrane oxidase complexes, cis-dihydrodiol-forming aromatic dioxygenases, bacterial assimilatory nitrite reductases, and arsenite oxidase. Rieske ferredoxins are also found as soluble electron carriers in bacterial dioxygenase and monooxygenase complexes.	1.06605e-20
NZ_CP021983.1|WP_080812872.1|389619_390450_+|hypothetical-protein	gnl|CDD|225464	COG2912, COG2912, Uncharacterized conserved protein [Function unknown].	3.62526e-68
NZ_CP021983.1|WP_080812866.1|393600_393981_+|DUF1622-domain-containing-protein	gnl|CDD|377914	pfam07784, DUF1622, Protein of unknown function (DUF1622). This is a family of 14 highly conserved sequences, from hypothetical proteins expressed by both bacterial and archaeal species.	4.12565e-21
NZ_CP021983.1|WP_080812922.1|390466_391249_-|ABC-transporter-permease	gnl|CDD|226218	COG3694, COG3694, ABC-type uncharacterized transport system, permease component [General function prediction only].	5.52762e-89
NZ_CP021983.1|WP_080812854.1|399137_400121_+|ABC-transporter	gnl|CDD|226952	COG4586, COG4586, ABC-type uncharacterized transport system, ATPase component [General function prediction only].	5.48738e-155
NZ_CP021983.1|WP_080812845.1|406385_406673_-|hypothetical-protein	gnl|CDD|226983	COG4636, Uma2, Endonuclease, Uma2 family (restriction endonuclease fold) [General function prediction only].	0.00306764
NZ_CP021983.1|WP_080812837.1|407762_408413_+|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	4.83823e-22

Protein sequences

>NZ_CP021983.1|WP_080812860.1|395116_397105_-|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein
MAFKDQQDPRNSPNSPGSNGSRFRWVGGGLLILLAGFLLLNVFTTARQSAQYSSIAYSKFLEQVESNQVKEATIRDDLIRYELESPITTEMNGEEQQQTLFQTVPPPNDPDLTAMLRSHDVEFSAVPSNDGGWGGFGWFLIPLLFLGLWSFLLRNRGGGPGGAAALGVGKSKARLYSEGDTRTTFEDVAGVDEAKAELQEVVDFLRNSDKYTRLGAKIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFLSISGSEFIELFVGVGASRVRDLFNQAKKQAPCIVFIDELDALGKSRGGQSPFAGGGMSEQEQTLNQLLNEMDGFDPNNGVILLAATNRPEVLDPALQRPGRFDRQVVVDRPDKIGRKDILAVHTPVVKLADDVDLETLAARTPGFAGADLANLVNEAALLAARRNGDEVTMADFSEAIERVIAGLEKKSRVLTDEERTTVAYHETGHAIVGSLMPGAGKVEKISIVPRGVGALGYTLQLPEEDRFLVREDELRGRIAILLAGRSAEEVVFGAVSTGAGDDIQKATDMAERCITVYGMSQKLGPIAFEKQQQQFMEGFGNPRRSVSPAVMETIDQEVKTIVDGAHHMALKILMHNRQVLEEMAQHLLEDEVLEKDALRQHLSQVSSPEAMAQWLDTGNLEDDVYLQDQLAGAQSS
>NZ_CP021983.1|WP_080812863.1|394129_394447_-|Mo-dependent-nitrogenase
MLGSIFSSLSGVAPVANGRQVDCLHPVRRRLNNLTVTTPGLAHRLVRLIPAQCPFERDIRLLGHRVAHIPPLCKFNPLYDELVALRFRALCYLADECGEDISAYI
>NZ_CP021983.1|WP_080812866.1|393600_393981_+|DUF1622-domain-containing-protein
MSLDVVSTEISTLVVLLNGILTSLCQLLALFVIAIGVTKALFIFLKDALIRPQTPDAFQRSRLAMGYSFSLGLSFLIGATILKTMISSRWDDIARLAAIIAVRTLLNYLLLQAINSSKPETNAVST
>NZ_CP021983.1|WP_088431481.1|392209_393211_+|DNA-ligase-associated-DEXH-box-helicase
MALITLRPEGLYCEAGDFFIDPWRPVEQALITHAHADHARSGSQQYLATQISEGILRKRLGPAISLRGVEYGERVRLGDTWVSFHSAGHVLGSAQIRVEHKGEVWVVSGDYKRCADPSCAPFEVVPCDVFVTEATFGLPVYHWQSGEAIAHQIYQWWQGDKERASLLFCYAFGKAQRILSELTRFTERPVYVHGAIQGLTESYRQAGVAMVPTIPTAAPVDNLTYASYAGELVLAPPAAHRSSWMKRFRHPQTAFASGWMAVRGARRRRGYERGFVLSDHADWSGLIDTIHQTQARQVYVTHGQSDALARYLQAFLQVAGQPLETQFDGEDDH
>NZ_CP021983.1|WP_088428923.1|391248_392079_-|multidrug-ABC-transporter-permease
MVNPRLQRPRILPALSRALAVSRAMLSVYYAYMVEYRAELILWVLSGTFPLILMGIWAEAATSGRFGLQPTDFIQYFLAVFIVRQLTVVWVVWEFEREVVEGKLSPYLLQPVDPVWRHVFSHVSERFARLPFVFLLLGLFMVLYPEASWWPTPINLALTLAAAGLSFCLRFLMQYTFALLAFWTERASAIEQFWFLIYTFLSGMVAPLEMFPDAVREIVLWTPFPYLIYFPARLLTNQAAQVSQGFLAMVIWLGLCFALNRWLWRQGLKQYSGMGA
>NZ_CP021983.1|WP_080812922.1|390466_391249_-|ABC-transporter-permease
MTRYLRVLQLFWSTAVAAELEYRLNFLIAALSSLGGLSGGLFGLFLFYRTGYQFQGWRWEEALMVLGTFTWLQGVSATFLVPNLNKIVTHVQEGTLDFILLKPISSQFWLSTRVLSPWGLPDMGFGLAMMFYGGYRLGLQPSDYLWGIPPLIFGAVSLYSLWFMLGATSIWFVKIYNVTEVLRGLLEAGRFPIVAYPTAYRVFFTFIVPVAFLTTVPAQTMLDRGHWGWILGSAALAAGLLQCSRWFWRFALRFYTSASS
>NZ_CP021983.1|WP_080812872.1|389619_390450_+|hypothetical-protein
MDFSLARQRFYQAVQQSDDHIDLAEAALYIAQENYPELDVQAYLNALDTMAAEARERLPQNPYPLKTLQAINHYLFDDLGFYGNADDYYDPRNSFLNDVIDRRTGIPITLCLIYLEITKRLDFPMAGVGMPGHFLVRPTLDDMAIFVDPFNQGEILFAEDCQERLQQIYGSRAKLQPQHLNVVTAKMLLARMLANLKVIYLQQRDIPKALAAIDRILLMLPKAAVELRDRGLIYYQLGRLVEAQHNLELYLCERPDANDAYEIRHIIQQIERVQGE
>NZ_CP021983.1|WP_088428921.1|388073_389618_+|FAD-dependent-oxidoreductase
MTLTETMLAPLGQTLTGLRRADALWQRYRLGQLAPSSVVTTSPQPLGAVDWDVVISGGTLGILLGAGLARRGWRVALLEKGKLRGRAQEWNISRRELQTLVELELLTSAQLEDAIATEYNPGRIQFQGGDPIWVRDVLNIGVDPVTLLEQLKQTFLAAGGQLFEDTAFQSAQVHPDGVHVDANQPFKTRLMIDAMGHFSPIVAQARGQEKPDAVCLVVGTCAQGMPHNDKGDLIVSFTPIRRQCQYFWEAFPARDGRTTYLFTYADAHPERPSLEALLEDYFSLLPQYQSVSLEALRLQRALFGFFPCYRDSPLTYPWDRLIPIGDSSGSQSPLSFGGFGAMIRHLPRLTQGVDDALQQDCLARADLAWLQPYQPSLSVTWLFQRSMSVPMDRSVSDPQQINRLLAAIFEDMAALGDEVLKPFLQDVVQFSPLARTLLQTSLHHPGLVLRLLPQLGLANLLDWMRHYASLGLYSSLYPLGRASQRWLEALPQSYYPHRWVEALQYGAGRDYSLH
>NZ_CP021983.1|WP_080812874.1|387600_387840_-|hypothetical-protein
MGKLAPKANPFMTYRDPNTGRWVTVVPKTTQALQWAASRPQETIEVLEPDQFWQLAHGAATCSDARQLDTSRELVTARN
>NZ_CP021983.1|WP_088428919.1|386957_387518_-|peroxiredoxin
MGLCRRTWLRWCFAVGLVVLSWLATTPSTLAMGGPQIPLGQMAPDFTLPTNADDGAISLSDYRGQWVVLYFYPQDFTSGCTLEAQRFQRDLDDYRRHNAQILGVSADDVASHDQFCDAEGLAFPLLSDPNGTVSQLYGAWLGFRSLRHTYVIDPEGVMRARFLGVRPAIHSQEVLAKLERLQIQAN
>NZ_CP021983.1|WP_080812858.1|397648_397882_+|hypothetical-protein
MPTHDPANPNPQSADTNPEDNVVDPRDLVYKGGYDKEPDKIVNNPAVTPPMPEDTQTSTASFISDTAEDDEAEWLLD
>NZ_CP021983.1|WP_080812856.1|397894_398458_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MWFPEMLAFKPRRPESGFTLIELLIVIIVLGILAALAYPSYLNMTRRARYAEAKIAMNAIAKELKIYRAEHNRYPAEVASGERPEGVINWPSRVPFDSSYDYDHWAIAAGECYVQVAFYGENQIRDYTTNVEVVPPPALETIDDDLVLAVERYACDEAPAGGSSGGSSGGGSSGGGSSGGGEGGEED
>NZ_CP021983.1|WP_080812854.1|399137_400121_+|ABC-transporter
MTKITVDNLSKAYPVAVKAAGMAGTLRHFFQRTYRLVEAVKQISFQVYPGEVVGFLGPNGAGKTTTLKMLTGLIHPSSGQVNVAGHVPFQRDAAFLRQITLVMGQKQQLLWDLPALDSLRINAAIYGLSAKEFHYRVHELAEMLSLREQLNQPVRKLSLGERMKAEMLAALLHRPQVLFLDEPTLGLDVNAQVAVRNFLLEYNRRYQATVLLTSHYMADITALCRRVLLIHRGQLIYDGSLEGLLSRFAPYREVKLDLESPVEAEHLRAYGEVESLQGCTASLIVRREALTQTVSRLLADLAVQDLRVTDPPIEEVIGRVFQAGTVA
>NZ_CP021983.1|WP_088428925.1|400179_401931_-|Rieske-(2Fe-2S)-protein
MVISQTPTQQKHLVQVAQVAEIEAAGVKVVHAEGHAIALFHHNGQIYAIDNRCPHMGFPLHKGSVKDCILTCHWHHARFDLTSGGTFDIWADDGQAFPVEVRDGVVWVDVTPPADAHAYHRQRLVDGLEQSLSLVIAKSVIAQLAAGVDPTEPFQTGLDFGVRYRRQGWGAGLTMHTCMMQLLPHLQASDRPRALYHGLSAVARDCAGKPPRFTIQPLPNTPASFQTLKQWFRQFIEVRDAQGAERCLASAVQVGAEPPQLADMLFAAATDHRFIDGGHALDFTNKALEALDSVHWQNAEQVLTSLVSEYAGAERMEESNAWRYPIDLVDILEQTFEALPEAIATGQAQQFSIHDAVDSLVSVLLGDDPQAIATTLLATLGQGCSPADLAGMVAYAAARRIAQFQTNNDFRDWDTAHHAFTFANAVHQGLTRVSSLELLRGVFDAAMAVYLNRFLNMPPARLPDLDNRVEEPAALLADLPDLLNRQQQVQAASTLVGTYLHSGGDPAQLLAMLGNLLLREDRDFHTIQNLEAALQQYQHWQGHEAGIHVLVATARYLAAHAPTMRSQTQTYEIAARLQRGDSM
>NZ_CP021983.1|WP_088428927.1|402593_403709_+|mechanosensitive-ion-channel-family-protein
MWQEVWNYGLWGNQVSDYALAIAILLIGVIAINIVRIVVINRLKNWAQRTATPLDDRLLHLLERPAVRLGYLGTFYVAISNLELHRILQQSIRVVCVIVATILVICLLGSLVEYAVRLYLVARRSDATLEQTVNAIVPAIKIVLWAVGLVFLLDNLGFDISAVVAGLGIGGIAVALAAQGLLQDLFSYFSILIDRPFEIGDFVVIGNLVGTVEHIGIKTTRLRSLSGEQLVAANTDLTSSRIQNYKRMERRRIAFALGVTYETPTAKLEALPEMIQQVIDNTANVSFDRAHFLSYGDFSLNYEVVYYVETSDYAIYMDAQQAINLELKRRFEAQGIDFAFPTQVLYTWHQNPAVSTNGKTAAAGELADVNP
>NZ_CP021983.1|WP_080812848.1|405647_406319_+|ribonuclease-III
MPSLPRFQNPALWQQAMTHSSYANESPDSGANNERLEFLGDAILTFLSGEFLFQRYPNWSEGELTPLRAALVDQQQLGQFAQQLNLGQQLRLSRGVEGSGGRTNPRLLSSAFEALIGAYFLDSGADMAQVRQYVVPFFESVIAERVASVQQLNPKSRLQEWALSHLGEIPRYTIVAASGPDHAKQFVAEVRLQGTPYGRGSGHRKQEAEKEAARQALKRLQHP
>NZ_CP021983.1|WP_080812845.1|406385_406673_-|hypothetical-protein
MPLSTSQIQTDTWIKATWGEFAAAMDDPQYEKGRGYFDNGYMRIEMAPLGAGHARQNTLISQVISLYGMLHSLRVVGLTNCSIYKPGARVYTNPR
>NZ_CP021983.1|WP_080812841.1|407068_407431_+|hypothetical-protein
MATVAILPISDSSGERAYRAISGDKHSTGKTVGQALDALTAQLGEVEFRALLLIQSCRPDPFFSAEQQGRLSELMDVWRAARDQGQELPIEQQDELNALVEAELRAATARTAALIQQGNL
>NZ_CP021983.1|WP_088428929.1|407427_407709_+|HNH-endonuclease
MNPLYAAVAERANHRCEYCQAPEVVFSFPFEVEHSVPLARQGPHDKTNLALAYRSCNLRKGLRISGTTSGGRVLSKYPPHYPTTLPSGKPLRV
>NZ_CP021983.1|WP_080812837.1|407762_408413_+|Uma2-family-endonuclease
MVDTASRPQGIETDTWIPATWEAFVTLSNRPGFDKARGYYDKGWMRLEMAALGPWHGRDNAVVLKVIGLFAGLTNIRAVELINTSFHKSGEREAQPDIAFYLGESFQLLPRTNQPVDVEVYGAPQLAVEIASTTLGDDLGRKRLLYERLGVQEYWVVNVAMSEVVTFAVENGGSREIRESQVLPGLALSTVEEAMQRSQTEDDGALTRWLIQTFQG

Crispr_ID: NZ_CP021983_2

• CRISPR_ID: NZ_CP021983_2
• CRISPR_location: 497487-497735
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 3 spacers
• Cas_protein_info: cas2,cas1

Consensus repeat of NZ_CP021983_2

Consensus_repeat	Method
GAAGGTTTCCGTCCCCTTGCGGGGTAATGGATTTTGAAC	CRT
GTTTCCGTCCCCTTGCGGGGTAATGGATTTTGAAC	CRISPRCasFinder
GAAGGTTTCCGTCCCCTTGCGGGGTAATGGATTTTGAACA	PILER-CR

spacers of NZ_CP021983_2

>2.1|497526|31|NZ_CP021983|CRT
CGGCTGTCCGAAGGCATTTTCCATGGGTTCG
>2.2|497596|29|NZ_CP021983|CRT
ATCACTCAGACTCAGCTAGAACAGGCGCT
>2.3|497664|32|NZ_CP021983|CRT
AGTTGGTCAGTCTTCGGATGACGCTAGCGACC
>2.4|497526|35|NZ_CP021983|CRISPRCasFinder
CGGCTGTCCGAAGGCATTTTCCATGGGTTCGGAAA
>2.5|497596|33|NZ_CP021983|CRISPRCasFinder
ATCACTCAGACTCAGCTAGAACAGGCGCTGAAG
>2.6|497664|36|NZ_CP021983|CRISPRCasFinder
AGTTGGTCAGTCTTCGGATGACGCTAGCGACCGAAG
>2.7|497597|28|NZ_CP021983|PILER-CR
TCACTCAGACTCAGCTAGAACAGGCGCT
>2.8|497665|31|NZ_CP021983|PILER-CR
GTTGGTCAGTCTTCGGATGACGCTAGCGACC

CRISPR arrays and Neighbor proteins around NZ_CP021983_2

CRISPR arrays

The CRISPR arrays of NZ_CP021983_2

>merge|NZ_CP021983|2|497487-497735|CRT,CRISPRCasFinder,PILER-CR
TACGGTTTCCGTCCCCTTGCGGGGTAATGGATTTTGAACCGGCTGTCCGAAGGCATTTTCCATGGGTTCGGAAAGTTTCCGTCCCCTTGCGGGGTAATGGATTTTGAACATCACTCAGACTCAGCTAGAACAGGCGCTGAAGGTTTCCGTCCCCTTGCGGGGTAATGGATTTTGAACAGTTGGTCAGTCTTCGGATGACGCTAGCGACCGAAGGTTTCCGTCCCCTTGCGGGGTAATGGATTTTGAACC

>NZ_CP021983|2|1|497487-497734|CRT
TACGGTTTCCGTCCCCTTGCGGGGTAATGGATTTTGAAC	CGGCTGTCCGAAGGCATTTTCCATGGGTTCG
GAAAGTTTCCGTCCCCTTGCGGGGTAATGGATTTTGAAC	ATCACTCAGACTCAGCTAGAACAGGCGCT
GAAGGTTTCCGTCCCCTTGCGGGGTAATGGATTTTGAAC	AGTTGGTCAGTCTTCGGATGACGCTAGCGACC
GAAGGTTTCCGTCCCCTTGCGGGGTAATGGATTTTGAAC

>NZ_CP021983|2|2|497491-497734|CRISPRCasFinder
GTTTCCGTCCCCTTGCGGGGTAATGGATTTTGAAC	CGGCTGTCCGAAGGCATTTTCCATGGGTTCGGAAA
GTTTCCGTCCCCTTGCGGGGTAATGGATTTTGAAC	ATCACTCAGACTCAGCTAGAACAGGCGCTGAAG
GTTTCCGTCCCCTTGCGGGGTAATGGATTTTGAAC	AGTTGGTCAGTCTTCGGATGACGCTAGCGACCGAAG
GTTTCCGTCCCCTTGCGGGGTAATGGATTTTGAAC

>NZ_CP021983|2|1|497557-497735|PILER-CR
GAAAGTTTCCGTCCCCTTGCGGGGTAATGGATTTTGAACA	TCACTCAGACTCAGCTAGAACAGGCGCT
GAAGGTTTCCGTCCCCTTGCGGGGTAATGGATTTTGAACA	GTTGGTCAGTCTTCGGATGACGCTAGCGACC
GAAGGTTTCCGTCCCCTTGCGGGGTAATGGATTTTGAACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_088428976.1|492869_493673_-|DUF4058-domain-containing-protein	unknown	unknown	gnl|CDD|379094
NZ_CP021983.1|WP_080811867.1|497963_498752_-|hypothetical-protein	unknown	unknown	gnl|CDD|378383
NZ_CP021983.1|WP_080811870.1|495936_496719_-|DUF4058-domain-containing-protein	unknown	unknown	gnl|CDD|379094
NZ_CP021983.1|WP_080811860.1|502184_503555_+|XRE-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379062
NZ_CP021983.1|WP_080811865.1|498754_499150_-|four-helix-bundle-protein	unknown	unknown	gnl|CDD|377534
NZ_CP021983.1|WP_080811879.1|487486_488122_-|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	gnl|CDD|275017
NZ_CP021983.1|WP_080811862.1|499627_499906_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NZ_CP021983.1|WP_088428980.1|505746_506772_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811907.1|490074_491367_+|FAD-binding-oxidoreductase	unknown	unknown	gnl|CDD|223354
NZ_CP021983.1|WP_080811872.1|493701_495906_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NZ_CP021983.1|WP_088428978.1|499905_501870_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|376633
NZ_CP021983.1|WP_080811869.1|496788_497145_-|four-helix-bundle-protein	unknown	unknown	gnl|CDD|274132
NZ_CP021983.1|WP_088428971.1|491363_491960_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811853.1|505266_505734_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088428975.1|492383_492632_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088428969.1|488433_489243_+|DUF4230-domain-containing-protein	unknown	unknown	gnl|CDD|379417
NZ_CP021983.1|WP_080811864.1|499193_499613_-|four-helix-bundle-protein	unknown	unknown	gnl|CDD|377534
NZ_CP021983.1|WP_088428973.1|492004_492217_+|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NZ_CP021983.1|WP_080811855.1|504515_505037_-|hypothetical-protein	unknown	unknown	gnl|CDD|225002
NZ_CP021983.1|WP_080811857.1|503743_504226_-|hypothetical-protein	unknown	unknown	gnl|CDD|227838

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP021983.1|WP_080811862.1|499627_499906_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	7.7e-29	94.5	0.1
NZ_CP021983.1|WP_088428978.1|499905_501870_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	3.9e-93	306.6	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_088428976.1|492869_493673_-|DUF4058-domain-containing-protein	gnl|CDD|379094	pfam13267, DUF4058, Protein of unknown function (DUF4058). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 244 and 264 amino acids in length.	1.60899e-128
NZ_CP021983.1|WP_080811867.1|497963_498752_-|hypothetical-protein	gnl|CDD|378383	pfam10087, DUF2325, Uncharacterized protein conserved in bacteria (DUF2325). Members of this family of hypothetical bacterial proteins have no known function.	1.66686e-05
NZ_CP021983.1|WP_080811870.1|495936_496719_-|DUF4058-domain-containing-protein	gnl|CDD|379094	pfam13267, DUF4058, Protein of unknown function (DUF4058). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 244 and 264 amino acids in length.	1.01114e-108
NZ_CP021983.1|WP_080811860.1|502184_503555_+|XRE-family-transcriptional-regulator	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	0.000123737
NZ_CP021983.1|WP_080811879.1|487486_488122_-|PEP-CTERM-sorting-domain-containing-protein	gnl|CDD|275017	TIGR04155, hypothetical_protein, PEP-CTERM protein sorting domain, cyanobacterial subclass. This domain model describes a subclass with family TIGR02595 of PEP-CTERM protein sorting signals associated with bacterial exosortases. This subclass is restricted to Cyanobacteria, including the genera Cyanothece, Nostoc, Trichodesmium, Lyngbya, Arthospira, etc. This PEP-CTERM subclass features strongly conserved residues within the transmembrane region, including a Gx4GxG motif. Model TIGR03763 describes a corresponding cyanobacterial form of exosortase found in most species with this domain.	4.59328e-06
NZ_CP021983.1|WP_080811865.1|498754_499150_-|four-helix-bundle-protein	gnl|CDD|377534	pfam05635, 23S_rRNA_IVP, 23S rRNA-intervening sequence protein. This family consists of bacterial proteins encoded within an intervening sequence present within some 23S rRNA genes. It folds into an anti-parallel four-helix bundle and forms homopentamers.	1.82764e-22
NZ_CP021983.1|WP_080811862.1|499627_499906_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.53726e-29
NZ_CP021983.1|WP_080811855.1|504515_505037_-|hypothetical-protein	gnl|CDD|225002	COG2091, Sfp, Phosphopantetheinyl transferase [Coenzyme metabolism].	2.39626e-32
NZ_CP021983.1|WP_080811872.1|493701_495906_-|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	7.23236e-11
NZ_CP021983.1|WP_088428978.1|499905_501870_-|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	1.31153e-108
NZ_CP021983.1|WP_080811869.1|496788_497145_-|four-helix-bundle-protein	gnl|CDD|274132	TIGR02436, S23_ribosomal_protein, four helix bundle protein. This family describes a protein of unknown function whose structure is a bundle of four long alpha helices. Some of the first members of this family were found encoded in the (atypically large) intervening sequence (IVS) of Leptospira 23S RNA, a region often present in the rRNA gene and removed during rRNA processing without re-ligation. However, this location is not conserved, and naming this protein as a 23S RNA protein is both confusing and inaccurate.	4.17984e-28
NZ_CP021983.1|WP_080811864.1|499193_499613_-|four-helix-bundle-protein	gnl|CDD|377534	pfam05635, 23S_rRNA_IVP, 23S rRNA-intervening sequence protein. This family consists of bacterial proteins encoded within an intervening sequence present within some 23S rRNA genes. It folds into an anti-parallel four-helix bundle and forms homopentamers.	4.6041e-17
NZ_CP021983.1|WP_080811907.1|490074_491367_+|FAD-binding-oxidoreductase	gnl|CDD|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	4.48535e-57
NZ_CP021983.1|WP_088428969.1|488433_489243_+|DUF4230-domain-containing-protein	gnl|CDD|379417	pfam14014, DUF4230, Protein of unknown function (DUF4230). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 203 and 228 amino acids in length.	5.90461e-38
NZ_CP021983.1|WP_088428973.1|492004_492217_+|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0.00292504
NZ_CP021983.1|WP_080811857.1|503743_504226_-|hypothetical-protein	gnl|CDD|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	0.00546797

Protein sequences

>NZ_CP021983.1|WP_080811869.1|496788_497145_-|four-helix-bundle-protein
MPSDLKQRTKAFALRIIRLYSALPNTTVAQVLGKQILRSGTSVGAHYREAHRARSTAEFVSKLNGGLQELEETNYWLELLAESETIEPSRLNPLSQEAGELTAIFVTLVKNAKNNEPA
>NZ_CP021983.1|WP_080811870.1|495936_496719_-|DUF4058-domain-containing-protein
MPSPFPGMDPYLEHPSAWPNIHHRLMTAIADGLAPKLLPKYQVLIEVRVYQVDGQNSVIVGRPDVAVAQGQRQLPKKTNAAATAPHPGDAVTVTLMLPETIRQGYLEIREIATSQVITVVEVLSPTNKRPGRSRAKYEVKRATLLSSPCNFVEIDLLRQWLSLDIPQEVEPSTYHILVSPQELRPQAKWYGFNLPDPIPCFELPLQPEDELPVVDLKGLLDGIYDRSGYGLVIDYSQSPVPPLDDANAAWAKEWLAKATQ
>NZ_CP021983.1|WP_080811872.1|493701_495906_-|tetratricopeptide-repeat-protein
MLPPAPLDQLGIDPARIGAVRPHHRRTHYQAIVNWLTKYQPPANATNLERVKGYLEAFYHLCDMGEWQRAASLIFTELNTPTKARLHYQLKLWGYTSEQTGLYAALIDHVDAKRNGMFLQFLGTSYYAQGNYREAKACLERSLRIFQEVGDPVNRGMVLSHLGDVYYALGNYQTAIEHYQDWLTITRQVGLRIGEGIALGSLGNIHEAQGNYLQALDYHHQHLAIARQEKDVEMEGAALGNLGSCCQALGQYEQARDYHRRHLHLAQTIGNRSGESSALGGLGSACYTLGEYELATQYFERQRQIARDIHDPLSEGNALGGLGNVCFATGHYDQALKLHQRHLAMAQRLDHQQSMLHALGNLGNVLSATGQYPDAIDCYRQQLTTAQAIGDQLGISLAYGNLGVVAYGLGNYQDALEALHWQLAIVRQMGDRYHESQALGNLGNVHGALGDNTQALQCFQQAMSIAQQLGDRQGEANALGYLGNISYRLGHFQAALDYHQRHWDLATALGDMPGQGRALEGLGHAHLKLGHNDLALSYYFQTLDLVRQVGDVAGEGAALGNIGNVYDEMHDYAGAITYHEQDLAIARRLGQQQGEEAALVNLANAHSELGHHHQAVELYHQALAMARQLGDRWGEGLTLSNLGETLMKLGQHQAALATLHAALEITREQQARSPEALTYRHLGMLYQAMGDPETAADYLDRAIALAADLELPSAAECRRLRSTLRVEERVTSIP
>NZ_CP021983.1|WP_088428976.1|492869_493673_-|DUF4058-domain-containing-protein
MASPFPGMDPYLETPELWSAVHSRLIVAIADELVDHLSQKYRVEVEKRVYFSSEDDSILVGIPDVAVATGRSAAGTTEAATLPPPMQPEPVTVPLAAEVTERYLEIREVATGMVVAVIELLSPKNKRPGEGRIAYLRKRNQVLASVSHLVEIDLLRGGQPLPMSGQHPSDYHILISRADRRPTADLYRFGLQQPIPSFPVPLLPGEKEPILALQPLLNRVYEKGRYHLAIDYGQPPVPPLSKQNEQWMAELLANYQLGATPGNETYD
>NZ_CP021983.1|WP_088428975.1|492383_492632_+|hypothetical-protein
MGHGVGLNADAGHPPPLTLHQGGAGTDEGIQHPVPGTHGKAVQIVADQMGRKRQHGTIPVMHRAIRQRKLIQHLTRPSLRLG
>NZ_CP021983.1|WP_088428973.1|492004_492217_+|hypothetical-protein
MRSHRFPVATDPPPAHPAVAAPHWPPGQTAGYWPPGPPSPGPSAHGRNSQSPAPAPGPPAIPGSCATAGG
>NZ_CP021983.1|WP_088428971.1|491363_491960_-|hypothetical-protein
MHRGDARQLPALLPPQSIDAVITSPPYPNEKDYTRTTRLESVLLGFIRDRGELRRVKQTLIRSNSRSIYSTDDDDRWIQDYPQILALAQEIERSRAQQGKTSGFSRLYSRVVTLYFGGMARHLAELRPILRPGAQLAYVVGDQASYLGVLIQTGQLLADIAACLGYEVTDIDLFRSRRVASKNLALREEVVVLRWPGP
>NZ_CP021983.1|WP_080811907.1|490074_491367_+|FAD-binding-oxidoreductase
MVTSLDQYTSLLGSAAVVPWSELDGAWQTALALASQDPPSCVVYPDSLEDLTAAVACAHDHGWRLLPCGHGSKLSWGGLAAGIEVAISTARLPQAVDHAVGDLTVTAAAGHSLAELQDQLGQEQQFLAVDPTYPQHATLGGIVATADTGALRQRYGGVRDMLIGVRFVRYDGQIVKAGGRVVKNVAGYDLMKLMTGSFGTLGVLAELTFRTYPQAPAVATVLLAGDDAAVKQSLAELRRSPLTPVALDLLSPALMVALGHEPSLGLAARFETVAAGVEEQVQRTLTLGQNHGLAGQTLEGEAGANLWATMTQILGEGAGILAKVGCLPVAAVDLLRQVDELGGLGRIHTGSGVGLVALGVGQDSQAILETMRSHCQAHQGYLTLLQAPLDLKQQLQVWGYSGNSLAVMEQIKQQFDPPRLLSPGRFVGGL
>NZ_CP021983.1|WP_088428969.1|488433_489243_+|DUF4230-domain-containing-protein
MRSAPPKPPDSSDQSEQTSAKKPSSRAQKKSRGFTPLAPVRFVQGVGTSLVGIAVVMALLAGVGVWRSGDRFLEGLRLMLTAPQPEPEVDVRSVIIHKLQGASELTTAIFAMEAVVPTTSDRTLAGYVIGKTNLLYIAYGEVRAGVDLSRLDPSQITTGPESVRIQLPPAQILDSKLDVERSEVYDYDRGFLGLGPDNAPELQEMAQRQALQKITRAACSEGILTAANERAQLVVSQLLSPLAFESVQVDTQTPDELTCAGLANSDTVN
>NZ_CP021983.1|WP_080811879.1|487486_488122_-|PEP-CTERM-sorting-domain-containing-protein
MLSTQRSAIAALAATSGIMALAIGPADAATVSGGVSLTGDVNIIRSDSGQVTFDFTGSPNGIVTGGTGDFSGLSSAVVSDLTFNPAGSSPSGPLFRADPLSTFIDFGAQTINGETNGLTFALTSPVQVVDLFESGPLTAFFTDKPLRGQFIFGDTTTAAGLLTAQQVPGAGSYSMSITTEPVPEPLTILGSTSALAMGALLKRRQARQASS
>NZ_CP021983.1|WP_080811867.1|497963_498752_-|hypothetical-protein
MHDLRGFRRLLMALYRQPWLWMRGISGADRREKRRLMRRLSTLKAECNVLRQEQEAIHHQLSLENRGLRTLYEDMKAERDDLQLEIWELEDLVEELFQLLTAVEAWQPTAESEPLAEIPFGPQTRVEDQPLDHQTDVSTQKSQANLQAIDVSGIKLALVGGHDATRRGVIDELTRQHGLAKWVELPPFSKHSLGRSNIKAKIHDCDLVVLITGYMKHKQTDSIMQLRKVECLSGDVLLLNCRGKSGVVREILAYISQKNCKV
>NZ_CP021983.1|WP_080811865.1|498754_499150_-|four-helix-bundle-protein
MQDFIHSYQELQVYQLAFDSSVEIYQLSQGFPEAEKDLLTRQMLTASRSACASIAAAWGKRRYRRAFVATLSDAQAEAAEMQTWIQIAMACGYLGGEAGQTLFGRYRLIFSALDRLIGDASVWLKPLGEEL
>NZ_CP021983.1|WP_080811864.1|499193_499613_-|four-helix-bundle-protein
MKLSVYSFQDLQVYQLAFRCSVEIYDLAQHFPEETSACLTRQILATSRAVRAHIAAAWGKRRDRKALITQLSEAQLKAAEMQTWIEAAVAVGYLDGDAGQALSDHYRRIFSSLDQLMEGALVGERRRSEDSTNDLPATA
>NZ_CP021983.1|WP_080811862.1|499627_499906_-|CRISPR-associated-endonuclease-Cas2
MFYLICYDIVLDRRRNKVAHLLEGYGMRVQKSVFECVLTPDQRDMLQRRLNRYIKPNEDQVRFYPLSPRYRQKVLVLGLQPQREVDDVAFIV
>NZ_CP021983.1|WP_088428978.1|499905_501870_-|CRISPR-associated-endonuclease-Cas1
MKLYVEQLATAWHLVQRGSRAAGIDGITVDLFTGIAREQIHQLYRQMRQERYVARPAKGFYLAKQKGGHRLIGIPTVRDRIVQRYLLQSIYPSLENAFSDAVFAYRPGLSIYAAVKRVMERYRYQPTWVIKADIQQFFDQLSWPLLLHQLDQLSLPATWVQWIEQQLKAGIVVSGQFYQPGQGVLPGSILSGALANLYLNDFDRHCLEADIPLVRYGDDCVAVCQSYLEASRSLALMQDWIEGLSLSFHPEKTTIIPPGQAFVFLGHRFRNGTVEGPARQKAEGRRQKAPQPGYGPPQLCSIVKSPRRMLATSTDDYWRDGMTTLYITDQGSYLRVRHQQFQVFHNQELRCSVPASRISHVVLFGCCNVSHGAVRLALQRRIPLLYLSNKGRYFGRLQTTGQAKLEYLTQQVYKAQDPDFVRTQAASIIIGKLHNSRILLLRLNRRRKTEAATQAIATLAELMQTVPSAESVEAMLGREGTGANLYFQAYASLLKGQFEFEKRTRPPTDPVNSLLSLGYTLLSQNVHAMVEGVGLHTHFGNLHKPQANRPSLVCDLVEEFRAIAVDSLVAYLINSNIFSPDDFTPPDARGGVYLHPDAMKRFLKHWEEKLQQSVTHPHSGYKVSYRRCLELQVWEYVACLMGEQPVYRPMQWEG
>NZ_CP021983.1|WP_080811860.1|502184_503555_+|XRE-family-transcriptional-regulator
MVALALERNGFLTQGDLAAHLEIALSTVSNFFRGINVSVAKFEEISAALGLEARELIQAQTASQPARTDAGMPMTFYAYDEGWVGRQEVIAELGPQVRGSCRLLMITGIAGVGKTALAERLSLELAGFGAPLRDPFDAQDQTLDFGSFAARLLEKLGQVVTPCDRTAIPQLMARLVQALQHQPRLLLIDSLEELLQGNEQDGWSEFKDEVFLQFFQRVLTAEEFQSRIILTSQELPTQLLSLGTRYQNFWTTHLLTGLSASEQLALFEKTGLDVRPDAAGRSYLVRMGQAYEGHPLALRVIAGEIGSRPFFGDVVAYWNRYGHEIEAVEVVIAAAAAGQAVGAEDKWRLDRFTRTLRRNVRQRLEQTFQRLRQDAKFAYILLCEASVYRCAVPEDWWLSHLDYWDCDQETGGLALDALRDRFLVEEAIESGQYTLRQHNLIRSVSLDHLQRLDEIW
>NZ_CP021983.1|WP_080811857.1|503743_504226_-|hypothetical-protein
MTPPSQKSATIAASQWPQTSELVGVQFSLAADRDYDLYPQYTIGLHAWFLQQIQQFDPELSAYLHDHESEKPFAITGLSGEFVAHSRALHIQRGQRYSWQVHGFSRRTVAGLATWLQQLPKTLVLKDLPLTIQRVRTVLPATTYAELAAAPWEGNTVSLS
>NZ_CP021983.1|WP_080811855.1|504515_505037_-|hypothetical-protein
MRYMSGWRRRSNANVSWLDAQERWRYERCRFPQHRHEYLVAHALLRSCLSRYGEQPPQDWRFSTNAYGRPEIQVEQGAPPRRFNLSHTEGLVACAITRAAEVGIDVEHGGQPVRAGDLAAIAVANFAPVELAELARLTGIAWRHRFFDVWTLKEAYIKAQGLGGAENYLGNRP
>NZ_CP021983.1|WP_080811853.1|505266_505734_-|hypothetical-protein
MKLFHYVRRDRAENFGDRLNLWLWPRQLPNAFEADEGVTFVGIGTLINHLLPQRLTTPEAIIFSTGVGYERPLERLPATWRIYCVRGPLSAQALGLSKQQGIADGGLLVSRHWPPATQRHTPVAFMPHIHHASREYEPERTLKQLLAYRAARDKA
>NZ_CP021983.1|WP_088428980.1|505746_506772_-|hypothetical-protein
MTPSVYFYLPQRFWPDALPQQAGEAWPGYVVGMYAWTIQTYLWLRERLACELVDTLPSAGIVLVHRNSLRAHAEPLRPHPERLLVCLQGDLPPYPQAQIHVVQNPLQADGRYRRLFLPHWPQPGLIPRDPSRRERFDTVAFFGHQDNLAGLGDDWTAALARLGLQWQPRLNRNRWNQSTGIHQRWHDYSDVDVVVAVRSWGWRPQWRTRCFGHKPATKLYNGWLAGVPVIAGLESAYRAERQSPLDYIEVKRPEDCLKALLRLQQETTLRRAMTHNAHRRSQTVRPDAIAHRWLAFFQEVAFPAYARWRTQSDWGRLWLIQRQQLAARWGRLESKLRSRVF

Crispr_ID: NZ_CP021983_3

• CRISPR_ID: NZ_CP021983_3
• CRISPR_location: 704215-707055
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 38 spacers

Consensus repeat of NZ_CP021983_3

Consensus_repeat	Method
GTTTCCATTAATTCGACTTCCGAAGAAGTT	PILER-CR
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	CRISPRCasFinder
GTTTCCATTAATTCGACTTCCGAAGAAGTTNNNG	CRT

spacers of NZ_CP021983_3

>3.1|704245|39|NZ_CP021983|PILER-CR
TTGGGAGGAGCATCCCGCTCCCCAGCCGGATCCAGAGCC
>3.2|704314|42|NZ_CP021983|PILER-CR
TTGGGTGAAGCGATTTGCTGAAACCATAATGCAAATCCTATC
>3.3|704386|40|NZ_CP021983|PILER-CR
TTGGGTCCAACTTGCAGCAATTGATCGCTTGACTCTGTTT
>3.4|704456|39|NZ_CP021983|PILER-CR
TTGGGTGGAGTTAACGCCCAAATCTCGTGTCCGAATATT
>3.5|704525|45|NZ_CP021983|PILER-CR
TTGGGTCGAGGCCAGCCCGACCACCACGACTACCACCTCCATCGG
>3.6|704600|41|NZ_CP021983|PILER-CR
TTGGGTGGGTGATTCGAATGTCCATGAAAACGCAAACCAAC
>3.7|704671|39|NZ_CP021983|PILER-CR
TTGGGCTTTGGGTGAAGGTGATTTCCAAATTGCCCTTGA
>3.8|704740|44|NZ_CP021983|PILER-CR
TTGGGGCGGATGCAACGGTGTTTAGATTTGTTAACAACTGTTCC
>3.9|704814|42|NZ_CP021983|PILER-CR
TTGGGAGGCTCTGCTGAAGTGCAAGTCCGGGGCGACCAAAAC
>3.10|704886|47|NZ_CP021983|PILER-CR
TTGGGTTGGGTCGCCGACACCTGCGACGAGAACGGCGAGAACATGGG
>3.11|704963|41|NZ_CP021983|PILER-CR
TTGGGAGCGCGATCAGTTCCTCGCGGAGGTTGCTAGCGATA
>3.12|705034|40|NZ_CP021983|PILER-CR
TTGGGGGCCCAACAGCAGCAACAAGCCGCAGAAGCCAGCA
>3.13|705104|46|NZ_CP021983|PILER-CR
GGCGACCCGCTACAGCTCCAGGTGCTCGGCTCTCCTAGATTCTCTG
>3.14|705180|41|NZ_CP021983|PILER-CR
GGCGACTGTATCTGTAGCCTTGTTTTCTAGCCTGGGGAGAG
>3.15|705251|45|NZ_CP021983|PILER-CR
GGCGACTTAAAGCTTACGAGAAAGGGCGAAGAGTGTTCTCTAGAT
>3.16|705326|46|NZ_CP021983|PILER-CR
GGCGACAGTTTCTGATACACTCGCAGGGCAATAGCCATCTCCGTTT
>3.17|705402|41|NZ_CP021983|PILER-CR
GGCGACCTAGGGATTTTCGCTGCTTTTTCGCTGCCTTCTGA
>3.18|705473|45|NZ_CP021983|PILER-CR
GGCGACGAAATACACCATCTGCCAGTACGCCCCGGGATACGTTGA
>3.19|705548|40|NZ_CP021983|PILER-CR
GGCGACTAAATATCGGGGGCTGCCCGTTGTTCCTCCTCAA
>3.20|705618|48|NZ_CP021983|PILER-CR
GGCGACCCGAGTCATTCGCAGAGTATTTAAGGGTTGAGCTCTGCGGAG
>3.21|705696|44|NZ_CP021983|PILER-CR
GGCGACGGCGATCGAGGCGATCGAGGCGGGAGATGCCAATGAGG
>3.22|705770|46|NZ_CP021983|PILER-CR
GGCGACGGAGTTGAAAAATGCAAGAGTATTCAGTTTGGGCGAGACG
>3.23|705846|42|NZ_CP021983|PILER-CR
GGCGACAAGGATCAATGGGTGACAGTCCGCACTGCAACCTTT
>3.24|705918|49|NZ_CP021983|PILER-CR
GGCGACTAAACCTATCCTCGTGTTTGTAATACAAGTTGTATTACAAGGA
>3.25|705997|48|NZ_CP021983|PILER-CR
GGCGACAAAAGGAGCATCGCCGTTTATTTGTTGGCGCTTATCTACAAT
>3.26|706075|42|NZ_CP021983|PILER-CR
GGCGACCCTTAAAGAATCGATAAGGGTGAAGGGTGATTACAA
>3.27|706147|48|NZ_CP021983|PILER-CR
GGCGACCTTTAACAATGTCCCATTCAAGATTAAGGACGGGTTCGAAGA
>3.28|706225|50|NZ_CP021983|PILER-CR
GGCGACCCAACGACGGGACAAAACAAGACTCCCCAACTCCCGCTGCTGAG
>3.29|706305|42|NZ_CP021983|PILER-CR
GGCGACTCGTAAATCTGTTGCAATTCAAGGCCCGTCGGTCGC
>3.30|706377|51|NZ_CP021983|PILER-CR
GGCGACCTCCAGACCCATAGGCTGAGGCTGAATTAACTGCTGTTTGCCTGC
>3.31|706458|40|NZ_CP021983|PILER-CR
GGCGACTCAGACAGGCGAGACCACAATTGACAAGTACGCA
>3.32|706528|41|NZ_CP021983|PILER-CR
GGCGACCTAAGGCACTCCTTAGTATTTCAGCTGGGGATTTA
>3.33|706599|40|NZ_CP021983|PILER-CR
GGCGACCTAAAAATATCCATATTGGACAAGCAGTACTCGG
>3.34|706669|46|NZ_CP021983|PILER-CR
GGCGACACTTGCTGTGCAGGTTGAATCATCCCCTCAGGCTATTTGA
>3.35|706745|45|NZ_CP021983|PILER-CR
GGCGACTTAATTGACTCTGGTCCCTCCGTCCATGTCTCTTTCCCA
>3.36|706820|49|NZ_CP021983|PILER-CR
GGCGACTTGGCCGCGTGGATGAACCAATCGGGGCGTGAAATAATTGTCT
>3.37|706899|48|NZ_CP021983|PILER-CR
GGCGACTCATTGATAACGAAGTACGTGAAATTAAAACAGTAAACCCAG
>3.38|706977|43|NZ_CP021983|PILER-CR
GGCGACCTCAATGATGTCGGACACTCTGGCAGCATGGCTTTGG
>3.39|704251|33|NZ_CP021983|CRISPRCasFinder
GGAGCATCCCGCTCCCCAGCCGGATCCAGAGCC
>3.40|704320|36|NZ_CP021983|CRISPRCasFinder
GAAGCGATTTGCTGAAACCATAATGCAAATCCTATC
>3.41|704392|34|NZ_CP021983|CRISPRCasFinder
CCAACTTGCAGCAATTGATCGCTTGACTCTGTTT
>3.42|704462|33|NZ_CP021983|CRISPRCasFinder
GGAGTTAACGCCCAAATCTCGTGTCCGAATATT
>3.43|704531|39|NZ_CP021983|CRISPRCasFinder
CGAGGCCAGCCCGACCACCACGACTACCACCTCCATCGG
>3.44|704606|35|NZ_CP021983|CRISPRCasFinder
GGGTGATTCGAATGTCCATGAAAACGCAAACCAAC
>3.45|704677|33|NZ_CP021983|CRISPRCasFinder
TTTGGGTGAAGGTGATTTCCAAATTGCCCTTGA
>3.46|704746|38|NZ_CP021983|CRISPRCasFinder
CGGATGCAACGGTGTTTAGATTTGTTAACAACTGTTCC
>3.47|704820|36|NZ_CP021983|CRISPRCasFinder
GGCTCTGCTGAAGTGCAAGTCCGGGGCGACCAAAAC
>3.48|704892|41|NZ_CP021983|CRISPRCasFinder
TGGGTCGCCGACACCTGCGACGAGAACGGCGAGAACATGGG
>3.49|704969|35|NZ_CP021983|CRISPRCasFinder
GCGCGATCAGTTCCTCGCGGAGGTTGCTAGCGATA
>3.50|705040|34|NZ_CP021983|CRISPRCasFinder
GCCCAACAGCAGCAACAAGCCGCAGAAGCCAGCA
>3.51|705110|40|NZ_CP021983|CRISPRCasFinder
CCGCTACAGCTCCAGGTGCTCGGCTCTCCTAGATTCTCTG
>3.52|705186|35|NZ_CP021983|CRISPRCasFinder
TGTATCTGTAGCCTTGTTTTCTAGCCTGGGGAGAG
>3.53|705257|39|NZ_CP021983|CRISPRCasFinder
TTAAAGCTTACGAGAAAGGGCGAAGAGTGTTCTCTAGAT
>3.54|705332|40|NZ_CP021983|CRISPRCasFinder
AGTTTCTGATACACTCGCAGGGCAATAGCCATCTCCGTTT
>3.55|705408|35|NZ_CP021983|CRISPRCasFinder
CTAGGGATTTTCGCTGCTTTTTCGCTGCCTTCTGA
>3.56|705479|39|NZ_CP021983|CRISPRCasFinder
GAAATACACCATCTGCCAGTACGCCCCGGGATACGTTGA
>3.57|705554|34|NZ_CP021983|CRISPRCasFinder
TAAATATCGGGGGCTGCCCGTTGTTCCTCCTCAA
>3.58|705624|42|NZ_CP021983|CRISPRCasFinder
CCGAGTCATTCGCAGAGTATTTAAGGGTTGAGCTCTGCGGAG
>3.59|705702|38|NZ_CP021983|CRISPRCasFinder
GGCGATCGAGGCGATCGAGGCGGGAGATGCCAATGAGG
>3.60|705776|40|NZ_CP021983|CRISPRCasFinder
GGAGTTGAAAAATGCAAGAGTATTCAGTTTGGGCGAGACG
>3.61|705852|36|NZ_CP021983|CRISPRCasFinder
AAGGATCAATGGGTGACAGTCCGCACTGCAACCTTT
>3.62|705924|43|NZ_CP021983|CRISPRCasFinder
TAAACCTATCCTCGTGTTTGTAATACAAGTTGTATTACAAGGA
>3.63|706003|42|NZ_CP021983|CRISPRCasFinder
AAAAGGAGCATCGCCGTTTATTTGTTGGCGCTTATCTACAAT
>3.64|706081|36|NZ_CP021983|CRISPRCasFinder
CCTTAAAGAATCGATAAGGGTGAAGGGTGATTACAA
>3.65|706153|42|NZ_CP021983|CRISPRCasFinder
CTTTAACAATGTCCCATTCAAGATTAAGGACGGGTTCGAAGA
>3.66|706231|44|NZ_CP021983|CRISPRCasFinder
CCAACGACGGGACAAAACAAGACTCCCCAACTCCCGCTGCTGAG
>3.67|706311|36|NZ_CP021983|CRISPRCasFinder
TCGTAAATCTGTTGCAATTCAAGGCCCGTCGGTCGC
>3.68|706383|45|NZ_CP021983|CRISPRCasFinder
CTCCAGACCCATAGGCTGAGGCTGAATTAACTGCTGTTTGCCTGC
>3.69|706464|34|NZ_CP021983|CRISPRCasFinder
TCAGACAGGCGAGACCACAATTGACAAGTACGCA
>3.70|706534|35|NZ_CP021983|CRISPRCasFinder
CTAAGGCACTCCTTAGTATTTCAGCTGGGGATTTA
>3.71|706605|34|NZ_CP021983|CRISPRCasFinder
CTAAAAATATCCATATTGGACAAGCAGTACTCGG
>3.72|706675|40|NZ_CP021983|CRISPRCasFinder
ACTTGCTGTGCAGGTTGAATCATCCCCTCAGGCTATTTGA
>3.73|706751|39|NZ_CP021983|CRISPRCasFinder
TTAATTGACTCTGGTCCCTCCGTCCATGTCTCTTTCCCA
>3.74|706826|43|NZ_CP021983|CRISPRCasFinder
TTGGCCGCGTGGATGAACCAATCGGGGCGTGAAATAATTGTCT
>3.75|706905|42|NZ_CP021983|CRISPRCasFinder
TCATTGATAACGAAGTACGTGAAATTAAAACAGTAAACCCAG
>3.76|706983|37|NZ_CP021983|CRISPRCasFinder
CTCAATGATGTCGGACACTCTGGCAGCATGGCTTTGG
>3.77|704249|35|NZ_CP021983|CRT
GAGGAGCATCCCGCTCCCCAGCCGGATCCAGAGCC
>3.78|704318|38|NZ_CP021983|CRT
GTGAAGCGATTTGCTGAAACCATAATGCAAATCCTATC
>3.79|704390|36|NZ_CP021983|CRT
GTCCAACTTGCAGCAATTGATCGCTTGACTCTGTTT
>3.80|704460|35|NZ_CP021983|CRT
GTGGAGTTAACGCCCAAATCTCGTGTCCGAATATT
>3.81|704529|41|NZ_CP021983|CRT
GTCGAGGCCAGCCCGACCACCACGACTACCACCTCCATCGG
>3.82|704604|37|NZ_CP021983|CRT
GTGGGTGATTCGAATGTCCATGAAAACGCAAACCAAC
>3.83|704675|35|NZ_CP021983|CRT
GCTTTGGGTGAAGGTGATTTCCAAATTGCCCTTGA
>3.84|704744|40|NZ_CP021983|CRT
GGCGGATGCAACGGTGTTTAGATTTGTTAACAACTGTTCC
>3.85|704818|38|NZ_CP021983|CRT
GAGGCTCTGCTGAAGTGCAAGTCCGGGGCGACCAAAAC
>3.86|704890|43|NZ_CP021983|CRT
GTTGGGTCGCCGACACCTGCGACGAGAACGGCGAGAACATGGG
>3.87|704967|37|NZ_CP021983|CRT
GAGCGCGATCAGTTCCTCGCGGAGGTTGCTAGCGATA
>3.88|705038|36|NZ_CP021983|CRT
GGGCCCAACAGCAGCAACAAGCCGCAGAAGCCAGCA
>3.89|705108|42|NZ_CP021983|CRT
ACCCGCTACAGCTCCAGGTGCTCGGCTCTCCTAGATTCTCTG
>3.90|705184|37|NZ_CP021983|CRT
ACTGTATCTGTAGCCTTGTTTTCTAGCCTGGGGAGAG
>3.91|705255|41|NZ_CP021983|CRT
ACTTAAAGCTTACGAGAAAGGGCGAAGAGTGTTCTCTAGAT
>3.92|705330|42|NZ_CP021983|CRT
ACAGTTTCTGATACACTCGCAGGGCAATAGCCATCTCCGTTT
>3.93|705406|37|NZ_CP021983|CRT
ACCTAGGGATTTTCGCTGCTTTTTCGCTGCCTTCTGA
>3.94|705477|41|NZ_CP021983|CRT
ACGAAATACACCATCTGCCAGTACGCCCCGGGATACGTTGA
>3.95|705552|36|NZ_CP021983|CRT
ACTAAATATCGGGGGCTGCCCGTTGTTCCTCCTCAA
>3.96|705622|44|NZ_CP021983|CRT
ACCCGAGTCATTCGCAGAGTATTTAAGGGTTGAGCTCTGCGGAG
>3.97|705700|40|NZ_CP021983|CRT
ACGGCGATCGAGGCGATCGAGGCGGGAGATGCCAATGAGG
>3.98|705774|42|NZ_CP021983|CRT
ACGGAGTTGAAAAATGCAAGAGTATTCAGTTTGGGCGAGACG
>3.99|705850|38|NZ_CP021983|CRT
ACAAGGATCAATGGGTGACAGTCCGCACTGCAACCTTT
>3.100|705922|45|NZ_CP021983|CRT
ACTAAACCTATCCTCGTGTTTGTAATACAAGTTGTATTACAAGGA
>3.101|706001|44|NZ_CP021983|CRT
ACAAAAGGAGCATCGCCGTTTATTTGTTGGCGCTTATCTACAAT
>3.102|706079|38|NZ_CP021983|CRT
ACCCTTAAAGAATCGATAAGGGTGAAGGGTGATTACAA
>3.103|706151|44|NZ_CP021983|CRT
ACCTTTAACAATGTCCCATTCAAGATTAAGGACGGGTTCGAAGA
>3.104|706229|46|NZ_CP021983|CRT
ACCCAACGACGGGACAAAACAAGACTCCCCAACTCCCGCTGCTGAG
>3.105|706309|38|NZ_CP021983|CRT
ACTCGTAAATCTGTTGCAATTCAAGGCCCGTCGGTCGC
>3.106|706381|47|NZ_CP021983|CRT
ACCTCCAGACCCATAGGCTGAGGCTGAATTAACTGCTGTTTGCCTGC
>3.107|706462|36|NZ_CP021983|CRT
ACTCAGACAGGCGAGACCACAATTGACAAGTACGCA
>3.108|706532|37|NZ_CP021983|CRT
ACCTAAGGCACTCCTTAGTATTTCAGCTGGGGATTTA
>3.109|706603|36|NZ_CP021983|CRT
ACCTAAAAATATCCATATTGGACAAGCAGTACTCGG
>3.110|706673|42|NZ_CP021983|CRT
ACACTTGCTGTGCAGGTTGAATCATCCCCTCAGGCTATTTGA
>3.111|706749|41|NZ_CP021983|CRT
ACTTAATTGACTCTGGTCCCTCCGTCCATGTCTCTTTCCCA
>3.112|706824|45|NZ_CP021983|CRT
ACTTGGCCGCGTGGATGAACCAATCGGGGCGTGAAATAATTGTCT
>3.113|706903|44|NZ_CP021983|CRT
ACTCATTGATAACGAAGTACGTGAAATTAAAACAGTAAACCCAG
>3.114|706981|39|NZ_CP021983|CRT
ACCTCAATGATGTCGGACACTCTGGCAGCATGGCTTTGG

CRISPR arrays and Neighbor proteins around NZ_CP021983_3

CRISPR arrays

The CRISPR arrays of NZ_CP021983_3

>merge|NZ_CP021983|3|704215-707055|PILER-CR,CRISPRCasFinder,CRT
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGAGGAGCATCCCGCTCCCCAGCCGGATCCAGAGCCGTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGTGAAGCGATTTGCTGAAACCATAATGCAAATCCTATCGTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGTCCAACTTGCAGCAATTGATCGCTTGACTCTGTTTGTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGTGGAGTTAACGCCCAAATCTCGTGTCCGAATATTGTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGTCGAGGCCAGCCCGACCACCACGACTACCACCTCCATCGGGTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGTGGGTGATTCGAATGTCCATGAAAACGCAAACCAACGTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGCTTTGGGTGAAGGTGATTTCCAAATTGCCCTTGAGTTTCCATTAATTCGACTTCCGAAGAAGTTTTGGGGCGGATGCAACGGTGTTTAGATTTGTTAACAACTGTTCCGTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGAGGCTCTGCTGAAGTGCAAGTCCGGGGCGACCAAAACGTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGTTGGGTCGCCGACACCTGCGACGAGAACGGCGAGAACATGGGGTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGAGCGCGATCAGTTCCTCGCGGAGGTTGCTAGCGATAGTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGGGCCCAACAGCAGCAACAAGCCGCAGAAGCCAGCAGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACCCGCTACAGCTCCAGGTGCTCGGCTCTCCTAGATTCTCTGGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACTGTATCTGTAGCCTTGTTTTCTAGCCTGGGGAGAGGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACTTAAAGCTTACGAGAAAGGGCGAAGAGTGTTCTCTAGATGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACAGTTTCTGATACACTCGCAGGGCAATAGCCATCTCCGTTTGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACCTAGGGATTTTCGCTGCTTTTTCGCTGCCTTCTGAGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACGAAATACACCATCTGCCAGTACGCCCCGGGATACGTTGAGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACTAAATATCGGGGGCTGCCCGTTGTTCCTCCTCAAGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACCCGAGTCATTCGCAGAGTATTTAAGGGTTGAGCTCTGCGGAGGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACGGCGATCGAGGCGATCGAGGCGGGAGATGCCAATGAGGGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACGGAGTTGAAAAATGCAAGAGTATTCAGTTTGGGCGAGACGGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACAAGGATCAATGGGTGACAGTCCGCACTGCAACCTTTGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACTAAACCTATCCTCGTGTTTGTAATACAAGTTGTATTACAAGGAGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACAAAAGGAGCATCGCCGTTTATTTGTTGGCGCTTATCTACAATGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACCCTTAAAGAATCGATAAGGGTGAAGGGTGATTACAAGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACCTTTAACAATGTCCCATTCAAGATTAAGGACGGGTTCGAAGAGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACCCAACGACGGGACAAAACAAGACTCCCCAACTCCCGCTGCTGAGGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACTCGTAAATCTGTTGCAATTCAAGGCCCGTCGGTCGCGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACCTCCAGACCCATAGGCTGAGGCTGAATTAACTGCTGTTTGCCTGCGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACTCAGACAGGCGAGACCACAATTGACAAGTACGCAGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACCTAAGGCACTCCTTAGTATTTCAGCTGGGGATTTAGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACCTAAAAATATCCATATTGGACAAGCAGTACTCGGGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACACTTGCTGTGCAGGTTGAATCATCCCCTCAGGCTATTTGAGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACTTAATTGACTCTGGTCCCTCCGTCCATGTCTCTTTCCCAGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACTTGGCCGCGTGGATGAACCAATCGGGGCGTGAAATAATTGTCTGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACTCATTGATAACGAAGTACGTGAAATTAAAACAGTAAACCCAGGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGACCTCAATGATGTCGGACACTCTGGCAGCATGGCTTTGGGTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC

>NZ_CP021983|3|2|704215-707049|PILER-CR
GTTTCCATTAATTCAACTTCCGAAGAAGTT	TTGGGAGGAGCATCCCGCTCCCCAGCCGGATCCAGAGCC
GTTTCCATTAATTCAACTTCCGAAGAAGTT	TTGGGTGAAGCGATTTGCTGAAACCATAATGCAAATCCTATC
GTTTCCATTAATTCAACTTCCGAAGAAGTT	TTGGGTCCAACTTGCAGCAATTGATCGCTTGACTCTGTTT
GTTTCCATTAATTCAACTTCCGAAGAAGTT	TTGGGTGGAGTTAACGCCCAAATCTCGTGTCCGAATATT
GTTTCCATTAATTCAACTTCCGAAGAAGTT	TTGGGTCGAGGCCAGCCCGACCACCACGACTACCACCTCCATCGG
GTTTCCATTAATTCAACTTCCGAAGAAGTT	TTGGGTGGGTGATTCGAATGTCCATGAAAACGCAAACCAAC
GTTTCCATTAATTCAACTTCCGAAGAAGTT	TTGGGCTTTGGGTGAAGGTGATTTCCAAATTGCCCTTGA
GTTTCCATTAATTCGACTTCCGAAGAAGTT	TTGGGGCGGATGCAACGGTGTTTAGATTTGTTAACAACTGTTCC
GTTTCCATTAATTCAACTTCCGAAGAAGTT	TTGGGAGGCTCTGCTGAAGTGCAAGTCCGGGGCGACCAAAAC
GTTTCCATTAATTCAACTTCCGAAGAAGTT	TTGGGTTGGGTCGCCGACACCTGCGACGAGAACGGCGAGAACATGGG
GTTTCCATTAATTCAACTTCCGAAGAAGTT	TTGGGAGCGCGATCAGTTCCTCGCGGAGGTTGCTAGCGATA
GTTTCCATTAATTCAACTTCCGAAGAAGTT	TTGGGGGCCCAACAGCAGCAACAAGCCGCAGAAGCCAGCA
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACCCGCTACAGCTCCAGGTGCTCGGCTCTCCTAGATTCTCTG
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACTGTATCTGTAGCCTTGTTTTCTAGCCTGGGGAGAG
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACTTAAAGCTTACGAGAAAGGGCGAAGAGTGTTCTCTAGAT
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACAGTTTCTGATACACTCGCAGGGCAATAGCCATCTCCGTTT
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACCTAGGGATTTTCGCTGCTTTTTCGCTGCCTTCTGA
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACGAAATACACCATCTGCCAGTACGCCCCGGGATACGTTGA
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACTAAATATCGGGGGCTGCCCGTTGTTCCTCCTCAA
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACCCGAGTCATTCGCAGAGTATTTAAGGGTTGAGCTCTGCGGAG
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACGGCGATCGAGGCGATCGAGGCGGGAGATGCCAATGAGG
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACGGAGTTGAAAAATGCAAGAGTATTCAGTTTGGGCGAGACG
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACAAGGATCAATGGGTGACAGTCCGCACTGCAACCTTT
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACTAAACCTATCCTCGTGTTTGTAATACAAGTTGTATTACAAGGA
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACAAAAGGAGCATCGCCGTTTATTTGTTGGCGCTTATCTACAAT
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACCCTTAAAGAATCGATAAGGGTGAAGGGTGATTACAA
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACCTTTAACAATGTCCCATTCAAGATTAAGGACGGGTTCGAAGA
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACCCAACGACGGGACAAAACAAGACTCCCCAACTCCCGCTGCTGAG
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACTCGTAAATCTGTTGCAATTCAAGGCCCGTCGGTCGC
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACCTCCAGACCCATAGGCTGAGGCTGAATTAACTGCTGTTTGCCTGC
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACTCAGACAGGCGAGACCACAATTGACAAGTACGCA
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACCTAAGGCACTCCTTAGTATTTCAGCTGGGGATTTA
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACCTAAAAATATCCATATTGGACAAGCAGTACTCGG
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACACTTGCTGTGCAGGTTGAATCATCCCCTCAGGCTATTTGA
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACTTAATTGACTCTGGTCCCTCCGTCCATGTCTCTTTCCCA
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACTTGGCCGCGTGGATGAACCAATCGGGGCGTGAAATAATTGTCT
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACTCATTGATAACGAAGTACGTGAAATTAAAACAGTAAACCCAG
GTTTCCATTAATTCGACTTCCGAAGAAGTT	GGCGACCTCAATGATGTCGGACACTCTGGCAGCATGGCTTTGG
GTTTCCATTAATTCGACTTCCGAAGAAGTT

>NZ_CP021983|3|3|704215-707055|CRISPRCasFinder
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGA	GGAGCATCCCGCTCCCCAGCCGGATCCAGAGCC
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGT	GAAGCGATTTGCTGAAACCATAATGCAAATCCTATC
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGT	CCAACTTGCAGCAATTGATCGCTTGACTCTGTTT
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGT	GGAGTTAACGCCCAAATCTCGTGTCCGAATATT
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGT	CGAGGCCAGCCCGACCACCACGACTACCACCTCCATCGG
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGT	GGGTGATTCGAATGTCCATGAAAACGCAAACCAAC
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGC	TTTGGGTGAAGGTGATTTCCAAATTGCCCTTGA
GTTTCCATTAATTCGACTTCCGAAGAAGTTTTGGGG	CGGATGCAACGGTGTTTAGATTTGTTAACAACTGTTCC
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGA	GGCTCTGCTGAAGTGCAAGTCCGGGGCGACCAAAAC
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGT	TGGGTCGCCGACACCTGCGACGAGAACGGCGAGAACATGGG
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGA	GCGCGATCAGTTCCTCGCGGAGGTTGCTAGCGATA
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGGGG	GCCCAACAGCAGCAACAAGCCGCAGAAGCCAGCA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	CCGCTACAGCTCCAGGTGCTCGGCTCTCCTAGATTCTCTG
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	TGTATCTGTAGCCTTGTTTTCTAGCCTGGGGAGAG
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	TTAAAGCTTACGAGAAAGGGCGAAGAGTGTTCTCTAGAT
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	AGTTTCTGATACACTCGCAGGGCAATAGCCATCTCCGTTT
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	CTAGGGATTTTCGCTGCTTTTTCGCTGCCTTCTGA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	GAAATACACCATCTGCCAGTACGCCCCGGGATACGTTGA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	TAAATATCGGGGGCTGCCCGTTGTTCCTCCTCAA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	CCGAGTCATTCGCAGAGTATTTAAGGGTTGAGCTCTGCGGAG
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	GGCGATCGAGGCGATCGAGGCGGGAGATGCCAATGAGG
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	GGAGTTGAAAAATGCAAGAGTATTCAGTTTGGGCGAGACG
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	AAGGATCAATGGGTGACAGTCCGCACTGCAACCTTT
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	TAAACCTATCCTCGTGTTTGTAATACAAGTTGTATTACAAGGA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	AAAAGGAGCATCGCCGTTTATTTGTTGGCGCTTATCTACAAT
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	CCTTAAAGAATCGATAAGGGTGAAGGGTGATTACAA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	CTTTAACAATGTCCCATTCAAGATTAAGGACGGGTTCGAAGA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	CCAACGACGGGACAAAACAAGACTCCCCAACTCCCGCTGCTGAG
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	TCGTAAATCTGTTGCAATTCAAGGCCCGTCGGTCGC
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	CTCCAGACCCATAGGCTGAGGCTGAATTAACTGCTGTTTGCCTGC
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	TCAGACAGGCGAGACCACAATTGACAAGTACGCA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	CTAAGGCACTCCTTAGTATTTCAGCTGGGGATTTA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	CTAAAAATATCCATATTGGACAAGCAGTACTCGG
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	ACTTGCTGTGCAGGTTGAATCATCCCCTCAGGCTATTTGA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	TTAATTGACTCTGGTCCCTCCGTCCATGTCTCTTTCCCA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	TTGGCCGCGTGGATGAACCAATCGGGGCGTGAAATAATTGTCT
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	TCATTGATAACGAAGTACGTGAAATTAAAACAGTAAACCCAG
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC	CTCAATGATGTCGGACACTCTGGCAGCATGGCTTTGG
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCGAC

>NZ_CP021983|3|2|704215-707053|CRT
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGG	GAGGAGCATCCCGCTCCCCAGCCGGATCCAGAGCC
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGG	GTGAAGCGATTTGCTGAAACCATAATGCAAATCCTATC
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGG	GTCCAACTTGCAGCAATTGATCGCTTGACTCTGTTT
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGG	GTGGAGTTAACGCCCAAATCTCGTGTCCGAATATT
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGG	GTCGAGGCCAGCCCGACCACCACGACTACCACCTCCATCGG
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGG	GTGGGTGATTCGAATGTCCATGAAAACGCAAACCAAC
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGG	GCTTTGGGTGAAGGTGATTTCCAAATTGCCCTTGA
GTTTCCATTAATTCGACTTCCGAAGAAGTTTTGG	GGCGGATGCAACGGTGTTTAGATTTGTTAACAACTGTTCC
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGG	GAGGCTCTGCTGAAGTGCAAGTCCGGGGCGACCAAAAC
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGG	GTTGGGTCGCCGACACCTGCGACGAGAACGGCGAGAACATGGG
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGG	GAGCGCGATCAGTTCCTCGCGGAGGTTGCTAGCGATA
GTTTCCATTAATTCAACTTCCGAAGAAGTTTTGG	GGGCCCAACAGCAGCAACAAGCCGCAGAAGCCAGCA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACCCGCTACAGCTCCAGGTGCTCGGCTCTCCTAGATTCTCTG
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACTGTATCTGTAGCCTTGTTTTCTAGCCTGGGGAGAG
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACTTAAAGCTTACGAGAAAGGGCGAAGAGTGTTCTCTAGAT
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACAGTTTCTGATACACTCGCAGGGCAATAGCCATCTCCGTTT
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACCTAGGGATTTTCGCTGCTTTTTCGCTGCCTTCTGA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACGAAATACACCATCTGCCAGTACGCCCCGGGATACGTTGA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACTAAATATCGGGGGCTGCCCGTTGTTCCTCCTCAA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACCCGAGTCATTCGCAGAGTATTTAAGGGTTGAGCTCTGCGGAG
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACGGCGATCGAGGCGATCGAGGCGGGAGATGCCAATGAGG
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACGGAGTTGAAAAATGCAAGAGTATTCAGTTTGGGCGAGACG
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACAAGGATCAATGGGTGACAGTCCGCACTGCAACCTTT
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACTAAACCTATCCTCGTGTTTGTAATACAAGTTGTATTACAAGGA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACAAAAGGAGCATCGCCGTTTATTTGTTGGCGCTTATCTACAAT
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACCCTTAAAGAATCGATAAGGGTGAAGGGTGATTACAA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACCTTTAACAATGTCCCATTCAAGATTAAGGACGGGTTCGAAGA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACCCAACGACGGGACAAAACAAGACTCCCCAACTCCCGCTGCTGAG
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACTCGTAAATCTGTTGCAATTCAAGGCCCGTCGGTCGC
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACCTCCAGACCCATAGGCTGAGGCTGAATTAACTGCTGTTTGCCTGC
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACTCAGACAGGCGAGACCACAATTGACAAGTACGCA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACCTAAGGCACTCCTTAGTATTTCAGCTGGGGATTTA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACCTAAAAATATCCATATTGGACAAGCAGTACTCGG
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACACTTGCTGTGCAGGTTGAATCATCCCCTCAGGCTATTTGA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACTTAATTGACTCTGGTCCCTCCGTCCATGTCTCTTTCCCA
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACTTGGCCGCGTGGATGAACCAATCGGGGCGTGAAATAATTGTCT
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACTCATTGATAACGAAGTACGTGAAATTAAAACAGTAAACCCAG
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG	ACCTCAATGATGTCGGACACTCTGGCAGCATGGCTTTGG
GTTTCCATTAATTCGACTTCCGAAGAAGTTGGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_080808994.1|708854_709520_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NZ_CP021983.1|WP_080809003.1|701305_701518_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080808996.1|707317_708100_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088429085.1|710274_710499_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080808988.1|709802_710270_+|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|350254
NZ_CP021983.1|WP_080808984.1|710912_711128_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080809006.1|701058_701244_+|hypothetical-protein	unknown	unknown	gnl|CDD|99749
NZ_CP021983.1|WP_080808976.1|712205_712571_-|hypothetical-protein	unknown	unknown	gnl|CDD|375906
NZ_CP021983.1|WP_080809001.1|701560_701704_+|hypothetical-protein	unknown	unknown	gnl|CDD|224485
NZ_CP021983.1|WP_088429080.1|699689_700274_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NZ_CP021983.1|WP_080809032.1|694859_695210_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080808992.1|709575_709779_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080808978.1|711637_712048_+|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|350312
NZ_CP021983.1|WP_088429083.1|708322_708847_+|DUF29-domain-containing-protein	unknown	unknown	gnl|CDD|366774
NZ_CP021983.1|WP_080808998.1|701936_703430_+|hypothetical-protein	unknown	unknown	gnl|CDD|379094
NZ_CP021983.1|WP_088429078.1|699147_699363_+|hypothetical-protein	unknown	unknown	gnl|CDD|377095
NZ_CP021983.1|WP_080809029.1|695249_695594_-|hypothetical-protein	unknown	unknown	gnl|CDD|317949
NZ_CP021983.1|WP_080808981.1|711407_711641_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088429076.1|695773_698347_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|378942
NZ_CP021983.1|WP_080809018.1|698420_698882_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_080808994.1|708854_709520_-|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	7.06532e-22
NZ_CP021983.1|WP_080809006.1|701058_701244_+|hypothetical-protein	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	1.41408e-05
NZ_CP021983.1|WP_080808988.1|709802_710270_+|PIN-domain-containing-protein	gnl|CDD|350254	cd18687, PIN_VapC-like, uncharacterized subfamily of the VapC (virulence-associated protein C)-like family of the PIN domain superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons. Matelska et al. recently classified PIN-like domains into distinct groups; this subgroup includes some sequences belonging to one of these, PIN_3.	0.00146137
NZ_CP021983.1|WP_080809001.1|701560_701704_+|hypothetical-protein	gnl|CDD|224485	COG1569, COG1569, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	4.39712e-08
NZ_CP021983.1|WP_088429080.1|699689_700274_-|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	2.89085e-29
NZ_CP021983.1|WP_080808978.1|711637_712048_+|PIN-domain-containing-protein	gnl|CDD|350312	cd18745, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily. The PIN_VapC4-5_FitB-like subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 ribonuclease toxins of the VapBC toxin/antitoxin (TA) system, and Neisseria gonorrhoeae FitB toxin of the FitAB TA system. This subfamily belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	7.84549e-57
NZ_CP021983.1|WP_088429083.1|708322_708847_+|DUF29-domain-containing-protein	gnl|CDD|366774	pfam01724, DUF29, Domain of unknown function DUF29. This family consists of various hypothetical proteins from cyanobacteria, none of which are functionally described. The aligned region is approximately 120-140 amino acids long corresponding to almost the entire length of the proteins in the family. Structure 3fcn is a small protein that has a novel all-alpha fold. The N-terminal helical hairpin is likely to function as a dimerization module. This protein is a member of PFam family PF01724. The function of this protein is unknown. One protein sequence contains a fusion of this protein and a DnaB domain, suggesting a possible role in DNA helicase activity (hypothetical). Dali hits have low Z and high rmsd, suggesting probably only topological similarities (not functional relevance) (details derived from TOPSAN). The family has several highly conserved sequence motifs, including YD/ExD, DxxNVxEEIE, and CPY/F/W, as well as conserved tryptophans.	8.81231e-07
NZ_CP021983.1|WP_080808998.1|701936_703430_+|hypothetical-protein	gnl|CDD|379094	pfam13267, DUF4058, Protein of unknown function (DUF4058). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 244 and 264 amino acids in length.	1.53322e-05
NZ_CP021983.1|WP_088429078.1|699147_699363_+|hypothetical-protein	gnl|CDD|377095	pfam03683, UPF0175, Uncharacterized protein family (UPF0175). This family contains small proteins of unknown function.	8.33487e-16
NZ_CP021983.1|WP_080809029.1|695249_695594_-|hypothetical-protein	gnl|CDD|317949	pfam15643, Tox-PL-2, Papain fold toxin 2. A papain fold toxin domain found in bacterial polymorphic toxin systems.	3.03411e-28
NZ_CP021983.1|WP_088429076.1|695773_698347_+|CHAT-domain-containing-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	1.79801e-68
NZ_CP021983.1|WP_080808976.1|712205_712571_-|hypothetical-protein	gnl|CDD|375906	pfam18480, DUF5615, Domain of unknown function (DUF5615). This is a domain of unknown function found in potential toxin-antitoxin system component.	1.09978e-06

Protein sequences

>NZ_CP021983.1|WP_080808998.1|701936_703430_+|hypothetical-protein
MTASNTVQMVGELLARWWRSLSHRLPDAIAAIAARTPQPHGRLPHPYDDRSQLLGWLLQPCWPLIQAQPETEILTALQQQVSLLGHGSCSRLIECHLGVAPALQHDLLRRLLTEPVPRYEDIKTALAQWIASLLPAHLEVADFPLGDRWEAFLYESWPPGWQIVLTLAVAHWAGRDQGLFNAILADGLFGPTHHLGANLMVLRESVMLGAAEWIAPYLASLPPDCAQTMNFAFLAKGLPAGAVKHMSPAGQEAIAQWLSPHVPDQAVTLWTLINHLADAAPTARELLIALVPQLPKKTRRQVEVQLLRFQPIAAHPPLETLSKSDQRFLLAMYQEWAQQDEAALERLLATARGKQNDAAVSASRVLADLDSGPVSLEDWVPLVRSRFVGVRVNALTAMATQLAKQSVADATLKDIAIALATEDNPTVGRKFCDLVAEWVRRRHRVPPVVSRCYLLPANKRLVGDARVSRERRPYAELYPFSMRDAMPRFAVPLTLQS
>NZ_CP021983.1|WP_080809001.1|701560_701704_+|hypothetical-protein
MILATAFTADANCIITGDKDLLVLQSIREVSILKPADFLAYEEAFNQ
>NZ_CP021983.1|WP_080809003.1|701305_701518_+|hypothetical-protein
MEQDFLITLTNDLKAELEAAASDEGQSAASLAQKAIADYLFSRQFRTLRAYLLAKAQDDYTDEDIFKIVS
>NZ_CP021983.1|WP_080809006.1|701058_701244_+|hypothetical-protein
MDDAMKLFGVLEYWIADREQRKLEVYRRDRGVLKLALSLYARDELTSPVLPDFRVQISQFF
>NZ_CP021983.1|WP_088429080.1|699689_700274_-|Uma2-family-endonuclease
MVQLKPRFQSFEEYLAYDDGTDNLYELFNGELIPVPPESGFNVEIANLLFALLLPLVGHRRMRGHGLELEVRGEPRNRFPDLTVIRDEHIAQLKARNTIRLSMAPPLLVMEIVSPGEVQRNRDYVAKRMQYQDLGIPEYWVIDPQAETILVLVLQEGVYREVATLTGEDAVVSTQLGALNILASETFTAGIGGG
>NZ_CP021983.1|WP_088429078.1|699147_699363_+|hypothetical-protein
MTSITFDVPQDVFSALKTSPDEFAAELRLAAAIFWYQKGQISQEKAAQVAGLDRNWPGSIPMLEVKRLLMI
>NZ_CP021983.1|WP_080809018.1|698420_698882_-|hypothetical-protein
MMRQWQTLAGTIVQGYRVASGLSQQSPYPGGTLAMQWPHFLARGVDLRPYFLGTLNVAIAPHQVRIVKPEITLEQMAWTDAHDPETFSFSRCRLTWNGNTFDGWIYYPHPETKPMHVQRPDHLEVLMPKIEGIGYGDRVELSVLADEVQILPG
>NZ_CP021983.1|WP_088429076.1|695773_698347_+|CHAT-domain-containing-protein
MSGGRQMGMGSQASGMLAVLLVVMGAEFPVAATASEPAALIAQEPEPDATAPLERAEALNQQVIELYQAGRYQEAIPLAEEALAIRRQQLGERHPHVAASLNNLALLYEAQGRYGEAEPLYQESLAIRRQQLGERHPAVAQSLNNLALLYVAQGRYGEAEPLYQESLAIRRQQLGERHPDVASSLNNLAGLYVDQGRYGDAEPLYQESLAILHQQLGEHHPKVAASLNNLAVLYYAQGETTQAVRSFQAGLAIEEWHLEINLTTLTEAQRQDYAATLFGTTDAAISLSLQSAEAPPLGLTTLLRRKGRLLEAGSSSLQRLRQNLTPEDQTLLDNLIDVRQQLAALTFNPPENLPPEEYRSQLAALEQQDSDLSATLARRSAVFRVEAEPVEIAAVQAQIPADGVLVEYARYHPFDAKANPANRWGDPRYAAYLLFPNGRIEAIDLGDAAAIDTAVQAFTTLLQDPRADLRGDPATIITEIDPDRIETVTSTLQALVLDPIAPYLEGREHLLISPDSQLNRLPFEALQTDDGRYLVEQYQISYLNSGRDLLKFDVLDPSTAPAVILANPDYEQAAPRLRSGLDSVTGSYPSGVVGEAAPKELESRGERSSSGVERSSSGVETNRRSTDLSQLQVEPLPGTAAEAGAIQPLLPNATVLTEDQATENVLKTVQAPRILHIATHGFFLEDQPIPVAEESRGLSLAAADGLRALPRLTAPVENPLLRSGLALAGFNARSSGDEDGVFTALEAANLNLFGTQLVVLSACDTGLGDIANGEGVYGLRRAFAIAGAETQLMSLWQVSDTGTQSLMARYYEKLMAGMGRSEALRAVQLEMIRAGGQYSRPYYWAAFILAGDWRPLE
>NZ_CP021983.1|WP_080809029.1|695249_695594_-|hypothetical-protein
MTRDEVFEEVAKIISGYTVFQCVDCAAAIKAWLKANGIHGVHLQMTAIGRLKFIVSQRWQAGLDCIAQSGVHQGIEIYGRVFDNLSSEGLKRAEWMADFDCASGEFEVIELEKF
>NZ_CP021983.1|WP_080809032.1|694859_695210_-|hypothetical-protein
MAGLYNLIRKIHQQPGLYVGTPSISNLYMFLCGYAFSRQEQGLEITAEEKEFEKFQTWIQQRFKISATVSWAQIILLHAADERSGFELFFELFSEFLAQHQDSENQQSIGQDRVVA
>NZ_CP021983.1|WP_080808996.1|707317_708100_+|hypothetical-protein
MDWISGIAQTPAPTAQELELLRQQIEFLKEANAELEETFARYVDMVQLTLKTAGGVVGVVAVLGAAVSIKSLQDFRATLKNVNTRVREEVEQVIAIALRQERQRLRRLESILAREDIPERLSLTYLVPSTRPQRQLPSLTRLLDILAGRGFQPKLSFQPSFSDPAAAQQQPDLTTDIVVLDLYHGGFALDTERANPTIQAVAAKLPSQQAALVVYGNARFYQAVTDLTEQGEYCGASNNPLSLVARVLEAAYVMDAVRAG
>NZ_CP021983.1|WP_088429083.1|708322_708847_+|DUF29-domain-containing-protein
MTQELMDLRRSLIEGRYEDALLLVDELESMGKQAILRNIESFLVRLLVHLIKNQVEQRLTHSWLVLISDSIVQISKLNLRDNKTSYYIKPDEWEPYLEDALAEAVLPASLETLEGKLKPKQLADRIDRSSVLAMAKRLLSLMYETPRRDLPARINTVLATLPGGAEWFETDDVV
>NZ_CP021983.1|WP_080808994.1|708854_709520_-|Uma2-family-endonuclease
MARTLTPAPATQRGEQRVALRGLAWQQYQQIYHALPQSRAAHLTYAEGTLEIVMPLEDHEYASELIGLFIRILAVEMGLRLKSLRSTTLNRPDLDRGAEPDNAYYIHNQPQVAGRTIDLAQDPPPDLVVEIDITSTDIDKNRLYAALGVPELWRYDGQTWRIYQLQGDSYQAVPHSPTFPWIAKADLYRFLETAQQDEVAAEIAFRTWVRQRLAAMSSPES
>NZ_CP021983.1|WP_080808992.1|709575_709779_+|hypothetical-protein
MPLAGDAIADLYEHLSQVSGGLEMRSRGSDVDTQSQKWPVPGESLLSAFGTDYMEGGEVGICEIGFC
>NZ_CP021983.1|WP_080808988.1|709802_710270_+|PIN-domain-containing-protein
MTQPYKIYLDVCCLNRPFDGWQQDRVRFEGEAVLTILQRVRAGEWQLISSEAVEAELERLPNPEKRESILQLLDLASMTVTLDAQIDQRSQALENLGFGLYDSFHIACAETTGVDILLTTDDRLLKRAARYKEDIWVQLMNPVPWLMDVLSIPEE
>NZ_CP021983.1|WP_088429085.1|710274_710499_+|hypothetical-protein
MTPIELRQRGYQALVDALGVVDAIRFLQQAGWGIGNYTTERHQWLTPVTRQEFWQDVQRIRDQKSHPLSSDSET
>NZ_CP021983.1|WP_080808984.1|710912_711128_+|hypothetical-protein
MSPSNLSQMTFDDLQQIIAQIVDERIEQYLASSPLKQPPIKETLSSISQHRWTPPPDAPTVVEMLRSDRER
>NZ_CP021983.1|WP_080808981.1|711407_711641_+|hypothetical-protein
MDTVKQRLIQELDKTPTPLLQEIFDFVLFLKQRYSQNQPHFSAGWQPNFFEEVIGSWEGEKLVREAQPDYEQREELL
>NZ_CP021983.1|WP_080808978.1|711637_712048_+|PIN-domain-containing-protein
MTAYLLDTNVCIKLLNGDNPRVIQRLAAQKPEEIYLCTITQLELFYGAYRGTKTDKNLPKLARFFSQFTILSFEPLAAEIAGKLRARLHQLGTPIGGYDLQIAAIALAYQLTLVTHNTREFGRVEGLLYEDWEAQP
>NZ_CP021983.1|WP_080808976.1|712205_712571_-|hypothetical-protein
MSLQYLLDEHIPPLYRTQLVRREPELIVRIIGDPDAPAKGTLDPDILIWCEVHNFILVTNNRKSMPKHLADHLAQDRHIPGILVMDLGRNIGEIIEELLIIAGASNDHEYQDRIEYLPLTL

Crispr_ID: NZ_CP021983_4

• CRISPR_ID: NZ_CP021983_4
• CRISPR_location: 713023-713160
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: cmr6gr7,cmr5gr11,cmr4gr7,cmr3gr5,cas10

Consensus repeat of NZ_CP021983_4

Consensus_repeat	Method
TCTATGAAAATATTAAGCAGTTGTCGGAGCGACTGCTAAGGGTTGGAT	CRISPRCasFinder

spacers of NZ_CP021983_4

>4.1|713071|42|NZ_CP021983|CRISPRCasFinder
GAGAGCGCATCATCGACTGGCCCGTGAGGGCGATCGCTGCCC

CRISPR arrays and Neighbor proteins around NZ_CP021983_4

CRISPR arrays

The CRISPR arrays of NZ_CP021983_4

>merge|NZ_CP021983|4|713023-713160|CRISPRCasFinder
TCTATGAAAATATTAAGCAGTTGTCGGAGCGACTGCTAAGGGTTGGATGAGAGCGCATCATCGACTGGCCCGTGAGGGCGATCGCTGCCCTCTATGAAAATATTGAGCAGTTGTCGGAGCGACTGCTAAGGGTTGGAT

>NZ_CP021983|4|4|713023-713160|CRISPRCasFinder
TCTATGAAAATATTAAGCAGTTGTCGGAGCGACTGCTAAGGGTTGGAT	GAGAGCGCATCATCGACTGGCCCGTGAGGGCGATCGCTGCCC
TCTATGAAAATATTGAGCAGTTGTCGGAGCGACTGCTAAGGGTTGGAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_080808994.1|708854_709520_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NZ_CP021983.1|WP_080808992.1|709575_709779_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080808968.1|714121_716251_-|hypothetical-protein	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl|CDD|224520
NZ_CP021983.1|WP_088431502.1|716205_716619_-|hypothetical-protein	cmr5gr11	cls000022_cmr5gr11_CAS-III-B	unknown
NZ_CP021983.1|WP_080808976.1|712205_712571_-|hypothetical-protein	unknown	unknown	gnl|CDD|375906
NZ_CP021983.1|WP_080808984.1|710912_711128_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080808956.1|719225_722513_-|hypothetical-protein	cas10	cd09679_cas10_CAS-III	gnl|CDD|378863
NZ_CP021983.1|WP_080808988.1|709802_710270_+|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|350254
NZ_CP021983.1|WP_088429089.1|723563_725744_-|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|143636
NZ_CP021983.1|WP_088429087.1|712585_712918_-|DUF433-domain-containing-protein	unknown	unknown	gnl|CDD|377269
NZ_CP021983.1|WP_088429085.1|710274_710499_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080808958.1|718029_719229_-|hypothetical-protein	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	gnl|CDD|187879
NZ_CP021983.1|WP_080808978.1|711637_712048_+|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|350312
NZ_CP021983.1|WP_088429083.1|708322_708847_+|DUF29-domain-containing-protein	unknown	unknown	gnl|CDD|366774
NZ_CP021983.1|WP_080808952.1|722962_723511_+|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|380360
NZ_CP021983.1|WP_080808970.1|713249_714083_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080808962.1|716705_717686_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	cd09682_cmr4gr7_CAS-III-B	gnl|CDD|274210
NZ_CP021983.1|WP_080808981.1|711407_711641_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088429091.1|726721_727774_-|L-histidine-N(alpha)-methyltransferase	unknown	unknown	gnl|CDD|378355
NZ_CP021983.1|WP_080808960.1|717746_717944_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP021983.1|WP_088431502.1|716205_716619_-|hypothetical-protein	cmr5gr11	cls000022_cmr5gr11_CAS-III-B	4.1e-13	44.6	0.2
NZ_CP021983.1|WP_080808956.1|719225_722513_-|hypothetical-protein	cas10	cd09679_cas10_CAS-III	1.7e-54	180.1	0.0
NZ_CP021983.1|WP_080808962.1|716705_717686_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	cd09682_cmr4gr7_CAS-III-B	3e-40	133.3	0.0
NZ_CP021983.1|WP_080808958.1|718029_719229_-|hypothetical-protein	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	1.7e-49	163.8	1.0
NZ_CP021983.1|WP_080808968.1|714121_716251_-|hypothetical-protein	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	2.6e-17	58.0	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_080808994.1|708854_709520_-|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	7.06532e-22
NZ_CP021983.1|WP_080808958.1|718029_719229_-|hypothetical-protein	gnl|CDD|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	1.68994e-40
NZ_CP021983.1|WP_088429083.1|708322_708847_+|DUF29-domain-containing-protein	gnl|CDD|366774	pfam01724, DUF29, Domain of unknown function DUF29. This family consists of various hypothetical proteins from cyanobacteria, none of which are functionally described. The aligned region is approximately 120-140 amino acids long corresponding to almost the entire length of the proteins in the family. Structure 3fcn is a small protein that has a novel all-alpha fold. The N-terminal helical hairpin is likely to function as a dimerization module. This protein is a member of PFam family PF01724. The function of this protein is unknown. One protein sequence contains a fusion of this protein and a DnaB domain, suggesting a possible role in DNA helicase activity (hypothetical). Dali hits have low Z and high rmsd, suggesting probably only topological similarities (not functional relevance) (details derived from TOPSAN). The family has several highly conserved sequence motifs, including YD/ExD, DxxNVxEEIE, and CPY/F/W, as well as conserved tryptophans.	8.81231e-07
NZ_CP021983.1|WP_080808988.1|709802_710270_+|PIN-domain-containing-protein	gnl|CDD|350254	cd18687, PIN_VapC-like, uncharacterized subfamily of the VapC (virulence-associated protein C)-like family of the PIN domain superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons. Matelska et al. recently classified PIN-like domains into distinct groups; this subgroup includes some sequences belonging to one of these, PIN_3.	0.00146137
NZ_CP021983.1|WP_088429091.1|726721_727774_-|L-histidine-N(alpha)-methyltransferase	gnl|CDD|378355	pfam10017, Methyltransf_33, Histidine-specific methyltransferase, SAM-dependent. The mycobacterial members of this family are expressed from part of the ergothioneine biosynthetic gene cluster. EGTD is the histidine methyltransferase that transfers three methyl groups to the alpha-amino moiety of histidine, in the first stage of the production of this histidine betaine derivative that carries a thiol group attached to the C2 atom of an imidazole ring.	1.7373e-161
NZ_CP021983.1|WP_080808976.1|712205_712571_-|hypothetical-protein	gnl|CDD|375906	pfam18480, DUF5615, Domain of unknown function (DUF5615). This is a domain of unknown function found in potential toxin-antitoxin system component.	1.09978e-06
NZ_CP021983.1|WP_088429089.1|723563_725744_-|HAMP-domain-containing-protein	gnl|CDD|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	7.35799e-49
NZ_CP021983.1|WP_088429087.1|712585_712918_-|DUF433-domain-containing-protein	gnl|CDD|377269	pfam04255, DUF433, Protein of unknown function (DUF433).	3.90199e-07
NZ_CP021983.1|WP_080808952.1|722962_723511_+|cupin-domain-containing-protein	gnl|CDD|380360	cd02232, cupin_ARD, acireductone dioxygenase (ARD), cupin domain. Acireductone dioxygenase (ARD; also known as 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase) catalyzes the oxidation of 1,2-dihydroxy-3-keto-5-methylthiopentene to yield two different products depending on which active site metal is present (Fe2+ or Ni2+) as part of the methionine salvage pathway. The ARD apo-enzyme, obtained after the metal is removed, is catalytically inactive. The Fe(II)-ARD reaction yields an alpha-keto acid and formic acid, while Ni(II)-ARD instead catalyzes a shunt out of the methionine salvage pathway, yielding methylthiocarboxylic acid, formic acid, and CO. ARD belongs to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	2.34172e-53
NZ_CP021983.1|WP_080808978.1|711637_712048_+|PIN-domain-containing-protein	gnl|CDD|350312	cd18745, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily. The PIN_VapC4-5_FitB-like subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 ribonuclease toxins of the VapBC toxin/antitoxin (TA) system, and Neisseria gonorrhoeae FitB toxin of the FitAB TA system. This subfamily belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	7.84549e-57
NZ_CP021983.1|WP_080808962.1|716705_717686_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl|CDD|274210	TIGR02580, putative_CRISPR-associated_protein, CRISPR type III-B/RAMP module RAMP protein Cmr4. This model represents a CRISPR-associated protein from the family that includes TM1792 of Thermotoga maritima. This family is part of the broad RAMP superfamily (pfam03787) collection of CRISPR-associated proteins. It is the fourth of a recurring set of six proteins, four of are in the RAMP superfamily, that we designate the CRISPR RAMP module.	2.41905e-34
NZ_CP021983.1|WP_080808968.1|714121_716251_-|hypothetical-protein	gnl|CDD|224520	COG1604, COG1604, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	4.23992e-14
NZ_CP021983.1|WP_080808956.1|719225_722513_-|hypothetical-protein	gnl|CDD|378863	pfam12469, DUF3692, CRISPR-associated protein. This domain family is found in bacteria and archaea, and is typically between 101 and 138 amino acids in length. The proteins in this family are frequently annotated as CRISPR-associated proteins however there is little accompanying literature to confirm this.	6.75431e-35

Protein sequences

>NZ_CP021983.1|WP_088429087.1|712585_712918_-|DUF433-domain-containing-protein
MNLQDYFTFLAPDDIRISGTRIGIESILYEYIYRGKTPEEIAQQFHTVTLEQVYATILYYLHNKEEVSAYIADWLEFARQQREQQRQHPSPARLRLRQLKPENIITQTTT
>NZ_CP021983.1|WP_080808976.1|712205_712571_-|hypothetical-protein
MSLQYLLDEHIPPLYRTQLVRREPELIVRIIGDPDAPAKGTLDPDILIWCEVHNFILVTNNRKSMPKHLADHLAQDRHIPGILVMDLGRNIGEIIEELLIIAGASNDHEYQDRIEYLPLTL
>NZ_CP021983.1|WP_080808978.1|711637_712048_+|PIN-domain-containing-protein
MTAYLLDTNVCIKLLNGDNPRVIQRLAAQKPEEIYLCTITQLELFYGAYRGTKTDKNLPKLARFFSQFTILSFEPLAAEIAGKLRARLHQLGTPIGGYDLQIAAIALAYQLTLVTHNTREFGRVEGLLYEDWEAQP
>NZ_CP021983.1|WP_080808981.1|711407_711641_+|hypothetical-protein
MDTVKQRLIQELDKTPTPLLQEIFDFVLFLKQRYSQNQPHFSAGWQPNFFEEVIGSWEGEKLVREAQPDYEQREELL
>NZ_CP021983.1|WP_080808984.1|710912_711128_+|hypothetical-protein
MSPSNLSQMTFDDLQQIIAQIVDERIEQYLASSPLKQPPIKETLSSISQHRWTPPPDAPTVVEMLRSDRER
>NZ_CP021983.1|WP_088429085.1|710274_710499_+|hypothetical-protein
MTPIELRQRGYQALVDALGVVDAIRFLQQAGWGIGNYTTERHQWLTPVTRQEFWQDVQRIRDQKSHPLSSDSET
>NZ_CP021983.1|WP_080808988.1|709802_710270_+|PIN-domain-containing-protein
MTQPYKIYLDVCCLNRPFDGWQQDRVRFEGEAVLTILQRVRAGEWQLISSEAVEAELERLPNPEKRESILQLLDLASMTVTLDAQIDQRSQALENLGFGLYDSFHIACAETTGVDILLTTDDRLLKRAARYKEDIWVQLMNPVPWLMDVLSIPEE
>NZ_CP021983.1|WP_080808992.1|709575_709779_+|hypothetical-protein
MPLAGDAIADLYEHLSQVSGGLEMRSRGSDVDTQSQKWPVPGESLLSAFGTDYMEGGEVGICEIGFC
>NZ_CP021983.1|WP_080808994.1|708854_709520_-|Uma2-family-endonuclease
MARTLTPAPATQRGEQRVALRGLAWQQYQQIYHALPQSRAAHLTYAEGTLEIVMPLEDHEYASELIGLFIRILAVEMGLRLKSLRSTTLNRPDLDRGAEPDNAYYIHNQPQVAGRTIDLAQDPPPDLVVEIDITSTDIDKNRLYAALGVPELWRYDGQTWRIYQLQGDSYQAVPHSPTFPWIAKADLYRFLETAQQDEVAAEIAFRTWVRQRLAAMSSPES
>NZ_CP021983.1|WP_088429083.1|708322_708847_+|DUF29-domain-containing-protein
MTQELMDLRRSLIEGRYEDALLLVDELESMGKQAILRNIESFLVRLLVHLIKNQVEQRLTHSWLVLISDSIVQISKLNLRDNKTSYYIKPDEWEPYLEDALAEAVLPASLETLEGKLKPKQLADRIDRSSVLAMAKRLLSLMYETPRRDLPARINTVLATLPGGAEWFETDDVV
>NZ_CP021983.1|WP_080808970.1|713249_714083_-|hypothetical-protein
MRKRNRSNIQEFIVQEWLRPLTFILCIAAAVIAIYKLIELPPTSPQVGQVESEVLARQLEFILKMNSAFLGFLGIIGALLTWFFKNSLDDAKKVAREIARQELATHLQPLVKEEIEDLDRSLLAERVVRETVIDYHLTSDRDISLLEHSLLEDRGFRVNKWHDLREERTPFAKVLVIDFVHSGILPNPYSTQNDDRQKIFQERENIFKHTISRILSSRKGNPILVIYIRPGEGRIAAIDTLTTDFSEIKYYTSANTPVALMGAVVDAAYVADSIYRS
>NZ_CP021983.1|WP_080808968.1|714121_716251_-|hypothetical-protein
MGVLGDRYSWGGKRITMASNNKNKTTLQDLAFLKNQLPSENKPNKNRSNKPSKKSRNSKILSPRNRSKIPLQVLKLDDLELSISGVKYDYEDFFSKQEVLSELLSIQGLSSRLREIKSLLESEKLNRGNSRKETDFEKILKRISKEKRNNACNCSAIKKEILDIDDKRVRVLLANAAGADKDWTDLYERLNQRVELLACEITDLATKNSKKAIVSVQYPWRVRVGGLQGFRERLLPAMHPIYGIPYIPASSIKGILRSWARDANKSSDEINHLLGFLQGEKASMAAVEILDAFPTAPSLSVDVATPQWIWQGDQVKYGPSPHQILSLQNLNFNIGLTHTSRGKAEDVQVVMDWLEQAMLTSGLGSRVSAGYGQAHQVNDLTRPEESSPYKSKHHFELWSQGIYGADSGQREFRPSAVRGMLRYWFRAVALGLYTPEHCKELEAKLFGALEPKAVHGSIDIKVEFEEDQSSLNDVNIPHKISGTVILEAQEPSHLALIQNVYKLAIHLGGVGRGARRPLHWNKDKKHSGLRGCYWEPEKKDRLDCNKGIWQDFLTSLETSFTDVRKADPRGALSPGNPGGPGKGKRNQDVLNVNSGIFLIPSPNMKHPNQVDDWPQEGQSSEIRGKALDFLYNPDYKGKNLQKIGNEFIGGELGTPSFVWISSNNLNIPNQSYQVVTVFGTDHVSENPLPGRQKFVEDLQNAVNFTAISV
>NZ_CP021983.1|WP_088431502.1|716205_716619_-|hypothetical-protein
MKKEKEERRLPNARPSEKEVNERTKSYCEKSSSLVQGLSTYIAAWGLHRLTGDAKKFSIGMASDTKYKGKVYGLFLERLKYLSKEEFVIWSHGYDASDEKTLVNMELRKYTALNRLAMQLAKEWGFWATAILGEAKE
>NZ_CP021983.1|WP_080808962.1|716705_717686_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MDNYLTYLYLFTPLHTGGSADEGNLMGIAREVHIEFPYMPASSVRGRIRAAMEQKYENDGLKDAVQTFFGQKIEGGGQPTEGEVWFADATLLFFPIASLSHHLVWITCPLWLERWSRWLGNDGDNVKTFAEDCHKKLKGLEGNKAKSAIATFKAEPLYLQTALLKPDDIDSSVDTQSLSKKIKAITAGNGIIGEIEQRLVVLSNEDCVSLVETGLQREVRVALNENEKTVKGGSFRSEEAIPPETVLFFPWATKPIRPFKPKPGMKPEEIDKAKAEHKTRVDNHEAVKASLQDMLGKRLQFGGLEGLGRGWSSLKTDKSKTQEAQS
>NZ_CP021983.1|WP_080808960.1|717746_717944_-|hypothetical-protein
MDSLRERYLVDNQGKRIGVVLDIGVYQKLLEELEELESLYAFDMAKADDDEAIPLEQAITEIERL
>NZ_CP021983.1|WP_080808958.1|718029_719229_-|hypothetical-protein
MTWYRITPLDVLLFRDSRPFSPTEGSWAKGLFPPMPITVFHGLRSLLTQRPRDERNKPRDLTFLGPFLCDDKNALWLPTPKDLVCLYPKDVGAKKASDNWKAVRCLQPAPQDDAWKYLAFADTYPAPPAPMVTPHEVYRETLSNKGKPKQRIGEPQPWMRAKYLAAYLDGKEGDWDPEKLLEKPLFHNDPWNVQVMPHIQMQSGTRQVQEADGYFTEVAVRMKPGWHFVACLESPGESLPEQGVIRLGGEGHRAMVEKMNDPDEPPEWEALSQRATNDGKLKRAYLLTPGLAQAEPGTPIYASYPEVWHDCLEGCATDKPLMWGGISAIERPGNSAKTDNNKDENWEVGYIPQRASVPPGTVYVFKSLPERKKLLPEDESRQWLTTFEMLNYGMLLWGA
>NZ_CP021983.1|WP_080808956.1|719225_722513_-|hypothetical-protein
MTDYQRKLYAFLHALHPDSTEPLPAPFGELACWENLEDLHDWWEQHGGKLTGDIAAASDRINLDTNADLPDEVEVRHPISGQRQTITKPSSVPPLPERSRREQSLLEDIPAEIQRSTDAEQVFWWFWRFYPEYLAKANSQALLYPAHRILPDCPLHSYQSTVSALVGALSNQDAEKPEDRIPYLLLFSFSPVQEFIKASRKFLDFWAGSYLLHHLSARLCWYVADKYGPDAVIVPSLWGQDIFDAFTLRDKYPDFAPVMACLADGRTPVARFDDRISNSLSTAGFPNMITALVPGKEAAEKLGQDLSNKLVEEWRTISEKIRDDIRDKVITFLTDDQHQTAREELWREFEKSANPELYRQEMELLQQQNCWEWRHLWEAQIDNTWEPYWAAVPLGNPEKDLLIKPEADQEGQWAKAQDAIAWPPTDLPSEAERRVYQKELNVGTWWGSLQQRLRTAHMAVKNTRHWKIPAAPGPRSTLSGQFSALHPRLNYQKRQLRNGETRDFREGGGLPESSMRLFWLIMSYAYKGLFNGSEMLNALELTKRMAWQFGGVAESMGISTALPVLSPEDYEDEDKADLHLQESRDEIDYEQLIRFPNLSSIAAARFMYESYNQPNSKLRAYWRVLKKKIGSGFENAQHQAQFAARTRGRPTHVWKTDNRINPSQAKKGKNYNGVMFSSKWLADDLNLEKHSENGDGNEVATLRRLVDEAHRHDEVNLGDGSPGDWWVIVLGDGDGMGSYISGETLKAYQEYLIDLEPNHYFNNRQGIDPAEFACHFYDLLDTPKRMGPATHIGLNRALLDFSNRLVPYLTEKRYCGRVIYSGGDDVMAVLPLEDLPGYLRSLRAAWSGGPDPDNEFLQYAPSTSMSSEDRLKGSGYWHPKAPLEGIPFRPHFTMGQDATMSLGIVIANKAVPLPTVLESLWDAEKTAKAMPGKDGLCFRVIYGGGNTLEALMKGELLDDWWALIDKGTQTKDGQDDLSPMLYRLAEELPKRASVTKDYNLFAEAAKVIVSNRDESKQFDDFEGFCDQLMAWLKRWEAWVKTVDPKQLQPGYDPRQDPPLTGTSPDALGYLLRFSAFWVSKNAQRRAWVQPVEVKS
>NZ_CP021983.1|WP_080808952.1|722962_723511_+|cupin-domain-containing-protein
MAILQLETGPRFTALEDIARELAPLGIELNHWPLGDEPEMGSLLAQPALDEAEKATVLEALDTYFETLKATAGYQSRDLIALHPQVPNLEALLAKFDKIHTHADDEVRYIIDGEGVFGFVRPDGSQVRLTVQPEEYINVPAGTEHWFYLTAARRIKAIRYFSGTDGWTPEYTGRQIRVPAMA
>NZ_CP021983.1|WP_088429089.1|723563_725744_-|HAMP-domain-containing-protein
MPLLKSRVKQALRRVIHKPTLRLVFTVPVLLQLVGAVGLVGYLSFRNGQQAVQDLASQLRSEISARIRRELQGYFGDPHAINRLNASAFTYGDLDVVDARYGEHLLFQQMKIYPTIAFVYCGSAKGGEFFGILRSPETGQLQLSYGNAANNFFRDYYSLDVRGQRLHRLYQADRPFDSRQRPWYRAAVETERPTWTDVYIAFTTGLPNVTASLPVYDQWGRQLLGVCATDVVLPEEFRTFLTNLEVGDSGQAFVIDRQGHLISSSTDEPLMVGTGEDAQFLMAVDSENPLVRQSVQHLLQRYQRLQSIQTPEQWAFEVDGERQFLEVLPFNDPFGLDWLILVVVPESDFMAQIHANTRTTVILCLVALLLAMVIGILSTRWVTSPILQLNAAVKEIAAGHYNRLVSVDRPDEVGELAKSFNSMVLRLQHSFQRLETQRNAFARFFPREYLTFLNKASVTEIELGDHVSKEMAVMFSDIRYFTSLAEKMAPQETFDFINTYLQKISPEIRAYQGFVVKFIGDGMMAIFPKRVEDALDAGIAQFQRVREYNAQRQTTGDFAIEIGIGIHVGHLMLGMIGEHHRIQGDALSDTVNLAARLEGLTKFFGVSLLMSGQVLQQLQDPSRYLIRSLGQAIVRGRTEPIAIYEVLDAEAEAERHLKQQTLPQFEQGVAAYCDRNLTLAQACFQQVLAVHPGDRIAQLYLERTNRLLADGIPADWVGVWSFTQKR
>NZ_CP021983.1|WP_088429091.1|726721_727774_-|L-histidine-N(alpha)-methyltransferase
MPTINPSATADNAASASTLAEQDRLTLEYLTAVTPEQADGLDVIQGLSQTPKSLPPKYFYDERGSRLFEQITQLPEYYLTRTETQILQQSADAIATLTGPCDLIELGSGSSTKTRLLLDAYQRQGTPLHYLPVDVSGTMVEESAQALLQHYPQLTLHGLIGIYEQVLAQLPPSRFPRRLLAFIGSTLGNLSDAECDQFLTQVSQALAPGDYFLLGLDLRKPVDVLEAAYNDSQGVTAAFNLNLLHHLNWRFQGNLDPSQFRHVAQYNPVADQIEIYIESLQAQTARLKALDLTVTFAAGERLLSELSRKFDLPTMAASLQSYGLHTVHTFTDPHHWFGLLLCQRQPPAPH

Crispr_ID: NZ_CP021983_5

• CRISPR_ID: NZ_CP021983_5
• CRISPR_location: 805950-806042
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: cmr5gr11,cmr4gr7

Consensus repeat of NZ_CP021983_5

Consensus_repeat	Method
GGGCGCCCAGGCTATTGGTCGGGGCGCACGG	CRISPRCasFinder

spacers of NZ_CP021983_5

>5.1|805981|31|NZ_CP021983|CRISPRCasFinder
GCTATCGGTCGGGGCGCCCAGGCTATCGGTC

CRISPR arrays and Neighbor proteins around NZ_CP021983_5

CRISPR arrays

The CRISPR arrays of NZ_CP021983_5

>merge|NZ_CP021983|5|805950-806042|CRISPRCasFinder
GGGCGCCCAGGCTATTGGTCGGGGCGCACGGGCTATCGGTCGGGGCGCCCAGGCTATCGGTCGGGCGCCCAGGCTATTGGTCGGGGCGCACGG

>NZ_CP021983|5|5|805950-806042|CRISPRCasFinder
GGGCGCCCAGGCTATTGGTCGGGGCGCACGG	GCTATCGGTCGGGGCGCCCAGGCTATCGGTC
GGGCGCCCAGGCTATTGGTCGGGGCGCACGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_080808801.1|801702_802617_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|369777
NZ_CP021983.1|WP_088429120.1|800225_801110_+|DUF4349-domain-containing-protein	unknown	unknown	gnl|CDD|379526
NZ_CP021983.1|WP_080808773.1|814400_816113_-|RAMP-superfamily-protein	unknown	unknown	gnl|CDD|213662
NZ_CP021983.1|WP_080808795.1|803110_803962_+|M56-family-peptidase	unknown	unknown	gnl|CDD|320685
NZ_CP021983.1|WP_080807200.1|813049_814282_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080808776.1|811216_811912_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080808787.1|807837_808392_-|hypothetical-protein	unknown	unknown	gnl|CDD|226983
NZ_CP021983.1|WP_080808813.1|798504_799599_+|low-complexity-tail-membrane-protein	unknown	unknown	gnl|CDD|380188
NZ_CP021983.1|WP_088429122.1|803996_804188_-|high-light-inducible-protein	unknown	unknown	gnl|CDD|177653
NZ_CP021983.1|WP_080808810.1|799828_800029_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080808770.1|816344_816767_-|hypothetical-protein	cmr5gr11	mkCas0065_cmr5gr11_CAS-III-B	unknown
NZ_CP021983.1|WP_080808785.1|808397_808982_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NZ_CP021983.1|WP_080808779.1|810790_811069_+|hypothetical-protein	unknown	unknown	gnl|CDD|225363
NZ_CP021983.1|WP_088429129.1|811964_813031_-|ISKra4-family-transposase	unknown	unknown	unknown
NZ_CP021983.1|WP_088429124.1|804292_804763_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080808782.1|809407_810589_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088429118.1|795490_798505_+|translation-initiation-factor-IF-2	unknown	unknown	gnl|CDD|235401
NZ_CP021983.1|WP_088429126.1|804870_805626_-|hypothetical-protein	unknown	unknown	gnl|CDD|236138
NZ_CP021983.1|WP_080808798.1|802691_803111_+|CopY-family-transcriptional-regulator	unknown	unknown	gnl|CDD|226207
NZ_CP021983.1|WP_080808767.1|816785_817835_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	gnl|CDD|224255

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP021983.1|WP_080808767.1|816785_817835_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	8.5e-21	69.3	0.0
NZ_CP021983.1|WP_080808770.1|816344_816767_-|hypothetical-protein	cmr5gr11	mkCas0065_cmr5gr11_CAS-III-B	2.2e-54	177.3	1.7

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_080808801.1|801702_802617_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	2.22155e-20
NZ_CP021983.1|WP_088429120.1|800225_801110_+|DUF4349-domain-containing-protein	gnl|CDD|379526	pfam14257, DUF4349, Domain of unknown function (DUF4349). This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 282 and 353 amino acids in length. There is a single completely conserved residue D that may be functionally important.	5.14421e-48
NZ_CP021983.1|WP_080808773.1|814400_816113_-|RAMP-superfamily-protein	gnl|CDD|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	0.000225146
NZ_CP021983.1|WP_080808795.1|803110_803962_+|M56-family-peptidase	gnl|CDD|320685	cd07326, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase. This family contains peptidase M56, which includes zinc metalloprotease domain in MecR1 as well as BlaR1. MecR1 is a transmembrane beta-lactam sensor/signal transducer protein that regulates the expression of an altered penicillin-binding protein PBP2a, which resists inactivation by beta-lactam antibiotics, in methicillin-resistant Staphylococcus aureus (MRSA). BlaR1 regulates the inducible expression of a class A beta-lactamase that hydrolytically destroys certain ?-lactam antibiotics in MRSA. Both, MecR1 and BlaR1, are transmembrane proteins that consist of four transmembrane helices, a cytoplasmic zinc protease domain, and the soluble C-terminal extracellular sensor domain, and are highly similar in sequence and function. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription. All members contain the zinc metalloprotease motif (HEXXH). Homologs of this peptidase domain are also found in a number of other bacterial genome sequences, most of which are as yet uncharacterized.	3.92206e-35
NZ_CP021983.1|WP_080808787.1|807837_808392_-|hypothetical-protein	gnl|CDD|226983	COG4636, Uma2, Endonuclease, Uma2 family (restriction endonuclease fold) [General function prediction only].	5.60814e-25
NZ_CP021983.1|WP_080808813.1|798504_799599_+|low-complexity-tail-membrane-protein	gnl|CDD|380188	NF033183, colliding_TM, low-complexity tail membrane protein. Members of this family appear typically as an unusual gene pair with members of PF11998 (DUF3493). Strangely, members tend to have tail-to-tail overlapping regions, where the tail region from this protein is long, low-complexity, and typically rich in Asp, Glu, Asn, Gln, Ser, and Thr. These gene pairs occur broadly in Cyanobacteria. The function of this pair of convergently-transcribed overlapping proteins is unknown. The low-complexity region was trimmed from the seed alignment to build this HMM.	1.53174e-83
NZ_CP021983.1|WP_088429122.1|803996_804188_-|high-light-inducible-protein	gnl|CDD|177653	PLN00014, PLN00014, light-harvesting-like protein 3; Provisional.	4.86525e-07
NZ_CP021983.1|WP_080808785.1|808397_808982_-|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	8.42234e-34
NZ_CP021983.1|WP_080808779.1|810790_811069_+|hypothetical-protein	gnl|CDD|225363	COG2804, PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion].	1.67121e-07
NZ_CP021983.1|WP_088429118.1|795490_798505_+|translation-initiation-factor-IF-2	gnl|CDD|235401	PRK05306, infB, translation initiation factor IF-2; Validated.	0
NZ_CP021983.1|WP_088429126.1|804870_805626_-|hypothetical-protein	gnl|CDD|236138	PRK07994, PRK07994, DNA polymerase III subunits gamma and tau; Validated.	7.67628e-05
NZ_CP021983.1|WP_080808798.1|802691_803111_+|CopY-family-transcriptional-regulator	gnl|CDD|226207	COG3682, COG3682, Predicted transcriptional regulator [Transcription].	2.43389e-31
NZ_CP021983.1|WP_080808767.1|816785_817835_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl|CDD|224255	COG1336, COG1336, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	9.97971e-16

Protein sequences

>NZ_CP021983.1|WP_088429126.1|804870_805626_-|hypothetical-protein
MTPSAAPQTLSNRQVIWVLAGSVGLALAVGSLVRLMTASPEQADVSTPKVVTETSPAPPLFTSPLASTTSLLTLADPGLLQPSDKAARLAQVTAGRTDPFAPLTRPSLTGPDAATATPVATAATTTPVAVATPPQSLPTVSVTAPPASLPPLPSREVAPETPAVAAASSPARNPVDALELSGVVQVGDRIHLIVKEPNAKTSRYVSVGDSLAGGRVRVHRIEMSEEPVVILAYNGQHYTRTIGSMVVAGML
>NZ_CP021983.1|WP_088429124.1|804292_804763_-|hypothetical-protein
MRLSLTNQYLCPVCRHGHIHALVLMESFSCDFCRHMFAANLSEQTIHMVDGTQPTGWRWNGRTWKSLRQGDLDMTLMVWIVGILLIIAPVGLISVSAYMFPPLDEALAWPIAWAIITLLTHMTLVVWLLAEHYQVSTYIAIKVRLRQLIERFQAIT
>NZ_CP021983.1|WP_088429122.1|803996_804188_-|high-light-inducible-protein
MKRAIRLNNFAVEPKVYGDDHQRFGFNRYAEQLNGRLAMIGFVSALLFEALTGQGVFGWLTRL
>NZ_CP021983.1|WP_080808795.1|803110_803962_+|M56-family-peptidase
MHLSLLLLIGLLAVVMRLLWPRPQGSWPQRWWSTLQGFSLPPLLLLTMALAVLGMGGHGHMLGLPVSHGGCGLALLWWGIALGHLVWAGGQMVRSHQQTKHLPVLALADDHPVSILPVAIPYAAQTGIWQPKTLLSQGLLQELNQEELSAVLAHEAAHCHYQDPFWFFWLGWLRRWSGWLPRSEDFWQDLLLLRELRADQWASQRVDPLLLASVLVKLAAMQQSLAIPGAISLHEASLNRLEERVDALLNAAATDSVDSPASVFPYPGWSMALLPLLTILLHQ
>NZ_CP021983.1|WP_080808798.1|802691_803111_+|CopY-family-transcriptional-regulator
MAPLPQKRPRQLSLGPLEQEIMAIIWQANLTTATAIHGYILRDPDRELAYASVMTVLQRLGKKGWVTCDRSQRPYRWYPVVSSQEAAVWKAHQQLADFLAVGNPDVVAAFADSLDTASVEQLDAIARRIQAIRQQRQAP
>NZ_CP021983.1|WP_080808801.1|801702_802617_+|class-I-SAM-dependent-methyltransferase
MTSSITQNSLYQPLHPFLVADHTVDFSGPIPVDTALTPSPAITANSNYFDHPDWALNYFNACHRTDGFKERWQAATGTWDDKIVVDVGCGPGNVFATVGGQPRLLIGVDVALGSLALAQEIGYVPLLADAHQMPLRSHMADLVLLNATLHHCENMERVLIEAARLVKPGGKLVIDHDPQLQAWNYRGLGMAMYRIRHHLYARCLKDLDMDPHERTYALATEIHHHPGHGVTAEFFRGSLGQLGFQVNLYPHNQTLGAETLQGQRGSFPHWRYPLGQILSGINPWSDEAALSLLCVAVRAVADYS
>NZ_CP021983.1|WP_088429120.1|800225_801110_+|DUF4349-domain-containing-protein
MVYRLPYWARGGVLLAALWLVGCGAISTPESTSNEAVSEAMTAENSAAPARQDQTAEVAADTSALPERQPQLVKQANMSLRLADVEAGIDAIYDLAVQQQGDILNLRDQQPDTGQPRQVSLRLRIPQSALEATLDALRQLGEVQQQQVTVTDVSNQLVDLQARLRNLRKSEETLLTLMERSGSVADVLQVAQELSNVRETIERLEAQRQQLNTQVTYATVQVQLEATVTPVPTNPPLAETLTNTWQQATHSVSDLSTGVLRLSLWLIAYSPYWALVLAAAWGYRRWQRQAQSSS
>NZ_CP021983.1|WP_080808810.1|799828_800029_+|hypothetical-protein
MTRLSSHQADQFADDATIWQSLKCAIANSSGFQRWQGEQSETDLAKTPLEQLVRRYLRETLETLAY
>NZ_CP021983.1|WP_080808813.1|798504_799599_+|low-complexity-tail-membrane-protein
MQSFRLDPYLWIHLAGLAAVPLWFDVCLLGLAAGDPVLPVWLELGVLAVVGVLPVLWMQWQRPFCIFSLVALALKPDQMSPNQRRLLHLFQDPIGRGVSLLVPLPLLWGLWQLYRLAPLAANSTPFSNRGVGVLVAAIAFLLVNLFTQVPVRVLRVLLAPATALDGVDPYAPEAIPQDFTLIGLRVNQILPPLEIPSAEAPPESPSQPAVTDQEEIAPAPLAKEDKEDGDETDDTIVSQTEPAPEEEPAAAEMAADVSTDAGLAAWPVDDSVEALDYEGQAPQPAESESVDSPEGDGQDGPESSSEESSAIESHVSSDAPQPDDSNGYHLQETDVQPPKGHSEHEHESSSQSPDEPGDAESRSE
>NZ_CP021983.1|WP_088429118.1|795490_798505_+|translation-initiation-factor-IF-2
MNNGKIRIYELSRELDLENKDILAICDRLNIAVKSHSSTITGEDAAQIRSAAKSARAGKAKPRQPEKAHNGARPPVRKQQILEIRRHRTAPKPPNAPEPPQSPEEPAAIDNDEVSQGEVDALMTPPSRPEAPTRPSSTQLKPPVSRPQSPGQAEAESPQPPKPKTASPPEPEEQPAEPSEDKATAPAAKAPSKPKPELIGPPPKPTRPKPKVTNRRAQADTSEPAAKSARQPTIPIREVDDDDDDGPKLKPKPKLRRPKPSEPQQDEQPVTPEQDDTEDSRDARDDSAREPLLKRPSPSRSQRRKTREEPVDEEQEMRPKADKKSKRRQAIIEDDDELEEVIEGGSGGQSDASSNLSVSLARPPKQKKASASKPSAPATRSYKPPSRDRSGSSRQQRRERQEQATQQERPEILTLTSELTVHELAAKIVVPETDIIKSLFFKGIAANINQTLDVPTAKMVAEEFDILVETAEAESEAKKITEMLDDSDLESLVRRPPVVTIMGHVDHGKTTLLDSIRKTKVAQGEAGGITQHIGAYHVDVDHEDDSQQIVFLDTPGHEAFTAMRARGARVTDIAILVVAADDGVRPQTIEAISHAKAAGVPIVVAINKIDKETAQPDRVKQELMEHGLVPEEWGGDAIMVPVSAIAGENLDNLLEMLLLVAEIEDLQANPDRLAKGTVIEANLDKARGPVATLLVQNGTLKVGDAVVAGSVFGKVRAMIDDRGQRVTSASPSFAVEVLGLNDVPAAGDEFAVYGDEKEARAVADSRATEQRQSRLQQAMASRRVTLSSLSAQAQEGDLKELNLLLKADVQGSLEAILAALQQLPQNEVQVRVLLAAPGEISETDVDLAAASGAVIIGFNTTLAPGARQAADRLGVDVRDYDIIYKLLEDIQGAMEGLLEPELVEESLGQVEVRAVFPVRKGSVAGSYVQSGKVTRNCHLRVLRQGEVVYTGKLDSLKRMKDDVKEVAAGFECGIGIDGFNDWKEGDIIEAFRLVTKRRTLAMAR
>NZ_CP021983.1|WP_080808787.1|807837_808392_-|hypothetical-protein
MTISTSSLTLEAFLKLPETKPASEFIDGKVIQKPMPQGEHSLLQGTLCETINQQAKAAKVAMAFPELRCTVAGRSIVPDVAVFRWSRIPRQPSGRIANRFTIHPDWSIEILSPEQSQTRVLGNLLHCAQQGTELGWLLDPEEETVLVVWSDQRVQLLRGDVPLPVLTDINLSLTADQLFGWLMV
>NZ_CP021983.1|WP_080808785.1|808397_808982_-|Uma2-family-endonuclease
MTPSTATTQISFEDYVAYDDGTAARYELVDGALVAMTPPTFRHMLIAKFIEQCLDTEIRRLGFRWLCFREAGIRTGVRKSRLTDVYVLTPEQVSNFLDESAICQTAPLLTVEVVSPESVSRDYRYKRTEYAALGVPEYWIVDPLQSTVTVLQLDEGMYEETVFVGHQPLVSPTFPELDLTVETLLAAGELAEEE
>NZ_CP021983.1|WP_080808782.1|809407_810589_+|hypothetical-protein
MKTIRSLRLSQRLPILLGVALTACAQITVTGLTQGEQANQTITVNALEIKRGRIDTLARVQTFQGQPAVDSINELAIQLSITEANNPPDFSETYYYLAISSPKEAILGGTTGDPNYVPNQIGKLTFLTLNQGDNRVEAAPQIGDAHAGASWLARVEADDRTIPWSITEGDNCFLLEAEEEDCFDMETLSRLLFETLADSIEQGMRNDIPAIQSIRHRLHFVPRVSHPAIGLNNRPAKGFGFIYFAQINVPGANFQVYIPINFLFIANVNQYILVVDPLELDTQDQKTIAQIYVKENIAGGIDLNLTEQIIRDQLIDQLQAAPLPVLIPGIDFSEALLTAMNGAAGNPSQLSDDFDILLSPSGENRDLATTILWEQLVPGNILPRNQVDLFFLE
>NZ_CP021983.1|WP_080808779.1|810790_811069_+|hypothetical-protein
MELLEVDDRIREIMYDGTITQLQHHLSKVGFLSFRGAAIEKLLTGATTSEEVLRVLPRSSLTRKTAADTEVLQLVPSGSDAFAVASEKLTYS
>NZ_CP021983.1|WP_080808776.1|811216_811912_-|hypothetical-protein
MLSEIRQDLDCLEKNDSKYSRYENYLKKHQIEFYYHEICATGTDRLLDAINEFWMNFIESTKYAADIASSILQAGEDSDEEEIYNCGSQLLTCIGLYEEKDFSELINIINEIIERWGFLISDDVCSLLTCLRDFFQNELESDEYLEEDQVKTYDEIKQRNELFDLIQNLPQVQFEQLLFIVKPPSNVIPKSSAAQGIRTYALLEWSESSSECGLQRIDEALKTLSTSLIRK
>NZ_CP021983.1|WP_088429129.1|811964_813031_-|ISKra4-family-transposase
MSPEDQAALAQHSREIAKILHRNSPPEAVDTLEGIETTVRQQMLEHVSPEVGNFFVEACTQTQRGRPRQLKSVLGTLPIREQQAQRLGLEPHGRLSPLFEKCALRVAACQSYGKGETDVSVLTGMSLSHSTLQRLVQRQRETPPEAKQTVTEISVDGGKVRLRHPEKGEPSYWKEYKSARVENLYYGAAFQANDWLQDWLNSQPLANPIICLGDGHRGVWAVFRPIATVETRLEILDWYHLVENLYGVGGSLKRLKQAKALLWEGRVDETQALFTDCALEQARRFCDYLERHRHRIVNYGYFQAEQICSIGSGAVESAIKQIDHRMKLPGAQWVPDNVQQALQVRCAYLNRAYDC
>NZ_CP021983.1|WP_080807200.1|813049_814282_-|hypothetical-protein
MSTRKRFYVFNIYGDSKVGKTFLLKEFRNIALENNSFTSLIQKDLNDIPSIMQKIYEDLKESEVSNPIFEEHYSTYIRLKSKLKNTTDIPEAYIDLIGSNLTNINDFRISPEKEKIKNRLDINRIGQDREIQEGFQKAILDLKKFIKSEIVNSDDRKLLENPIDVLTFELLRALRSAAIDQPIVLFFDDYHINKNILDPWLIGLVETVGSSRGLPGNSIVVISGREKLDRETWLLFDSFISDVKLNRFRANDISVILDHQGIKDEIIKRFISKLTGGVPLHLKDLVKDLRNITKNNIHLDETIVLECYLNNRKTLINRKIFLDLAVPRIINESIYNLLVGTRLKQTSFELFTTIPFLIHRSDGWLYDSLIREKTISYRRSTLNPELQETHRRLGSISFLREPSICAEMKG
>NZ_CP021983.1|WP_080808773.1|814400_816113_-|RAMP-superfamily-protein
MSTLTDAANKVPLMFRAQVEGRCQVQRLIPKALEQDAERWADEWVDKAYPDAPNFGKDVQTRPYALSWRFITNSGQDDGVIRPVIGARGWPFYPGSSMKGVFRQAAHQLERAGELKLGTCDRYCGEKLENNDFRPGILRFHGGYPTDTRWTQNLVDIVHPQQQWQVKSNDKEGGAFIQISLYKPELIVGISSTTPLDDLEWEQIWHIWETALSLGLGCRVSAGYGQPQQRSGDILYRTRLKGQGQAAKLVDGTGEFRPNVFRAAIRGHALRIFGGLTNADQAEGLVQDLFGGIRGGATVGLLSMAFLDTQLELDDFGQGSYSQPTYTVEGELLWRLTRDLPQPQRQALTKLIEALTRFAMVFGGFGKSWRRADHRLVYPDYYDQGYKPLIGCHWEWLGKRSQVRDVRVRKLEKVGDFIAEVRQAAKEWMQLQTRTPQLDTHANWREAWHPDKVQVWGRETDGLEDCEAVRWLHGPYREAIPSVGIPEGSIYRSSITGQMGNVGRLWHRMYPKVRLVKDPENPKKPMPLVTRQYFELVTVFPDDSVESEQLLGFLNGQQTLFKKLWPMPRH
>NZ_CP021983.1|WP_080808770.1|816344_816767_-|hypothetical-protein
MGWQAYGLDREAQWLVLQALDIDNDKDIKGDACLRESYKMRESVAYGLERFWGEHMRHQGKQEKKSRYWKATWDILANILGPADVTLPNDSDPKAMAQKLWGEIPVDSSGKMLTLEDQRLALAVLTQLCDCLVWWTQRYK
>NZ_CP021983.1|WP_080808767.1|816785_817835_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MYHRAYGIIETLAPLHVGASAGEETGNLNLIFRDQFTQTGIIPGSSIRGRFRADMRLRRQQHLEASLKAAGVDLPAATARKVSSPEDPKKRLPRLEWLEQEAEKQSISVPELVNENHWYGHHAVTGQEDGGTTEALVKFEYASLVWIPVFCPGQPVVWVSCPRLLRRYKQITGKPEPVLRPKAAADGQPKQYPVKLREHRDRLFFNLGFLDNLAETPDLSNWVPKDSQIQPDNLVVVDDQDISIIHDMALYRQTRTKLEDDVKKVENFFGFEALPEDSILIFPIAVKDSVPHYDRASDASADGSARWKPFKNRTLRELYFGGLESIGCGHCEVTLAGDYFGDTPDDADA

Crispr_ID: NZ_CP021983_6

• CRISPR_ID: NZ_CP021983_6
• CRISPR_location: 826073-832012
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 77 spacers
• Cas_protein_info: cas2,cas1,cas10,cmr3gr5,cmr4gr7,cmr5gr11

Consensus repeat of NZ_CP021983_6

Consensus_repeat	Method
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CRISPRCasFinder
NNCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CRT
TTCCGAATTAACCCAATCG	PILER-CR
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CRISPRCasFinder

spacers of NZ_CP021983_6

>6.1|826109|34|NZ_CP021983|CRISPRCasFinder
CGCTTGAACACCCGGATCAGTATCCGCAGCGATC
>6.2|826179|43|NZ_CP021983|CRISPRCasFinder
TCACAGTCCTCGCTGAATTCGCTTCATTTTGAGCCACTCACCA
>6.3|826258|48|NZ_CP021983|CRISPRCasFinder
TCAGGGAACAAATTGATTTTGCCGTTCACCCAAATTGCGGCATAGATT
>6.4|826342|39|NZ_CP021983|CRISPRCasFinder
TCTTTATGCTCTGGTCTGTAGAGCTCTGGATTCAGCATC
>6.5|826417|38|NZ_CP021983|CRISPRCasFinder
TGATTAAGTTCGGGAACACAACCATCTGCAGTGTTATG
>6.6|826491|41|NZ_CP021983|CRISPRCasFinder
CCTCGATGTCCTTGAAGTTTTATAGGCTCTTTAGTATCCGC
>6.7|826568|39|NZ_CP021983|CRISPRCasFinder
CTTCTGCTAAGAAAGGATCCATCGTCAAACACGATAAAC
>6.8|826643|40|NZ_CP021983|CRISPRCasFinder
GCTGACGTAGCGCAAACCATTCTTCAGCCAGGAAGCTTGG
>6.9|826719|44|NZ_CP021983|CRISPRCasFinder
CCGTAGGCCCCATTTGCAACTGCGCGAATACAGGATTCCGTGCC
>6.10|826799|43|NZ_CP021983|CRISPRCasFinder
AGCAAGGGTTTCAGCCATTCCTCTCCCTTTGCTATACTCTTCC
>6.11|826878|43|NZ_CP021983|CRISPRCasFinder
TCGGGTATCAGTGCTGCTCCTAGTGCCTTAACCCCAACTCAAC
>6.12|826957|41|NZ_CP021983|CRISPRCasFinder
TTTGGAAAGTAGTTTATATAAATTTAGATGACTCCGAAAGC
>6.13|827034|41|NZ_CP021983|CRISPRCasFinder
TAAATACGGGTGGACCTTCAAAGATTTTGATTCTGTTGACC
>6.14|827111|41|NZ_CP021983|CRISPRCasFinder
TTATTCGAACCACTTGGATAAAGTCAACGAACAATTGACCC
>6.15|827188|44|NZ_CP021983|CRISPRCasFinder
GCGGGGAGCAGTCAACAGGTTGGTGAGTTTCTCATGTATGTTGC
>6.16|827268|49|NZ_CP021983|CRISPRCasFinder
CGTAACAGAGGTGGTCTAAGCTCTAAAACCCTTGCTGTGTAGGAGTTCC
>6.17|827353|38|NZ_CP021983|CRISPRCasFinder
AGTTCCTCCAAAAGATGTTTCTCAGAGTGTGGCGACCC
>6.18|827427|39|NZ_CP021983|CRISPRCasFinder
AATAATCAGTATAAAACTGCCCATTCGTAATACAAACAC
>6.19|827502|43|NZ_CP021983|CRISPRCasFinder
CCTAGTAATCCCCTGTTTGTTTTTGTAAGGGTAAGGCCGGTTG
>6.20|827581|38|NZ_CP021983|CRISPRCasFinder
GAAGGACGCATTATTGATCTTACTGGCGCAACCAACCC
>6.21|827655|44|NZ_CP021983|CRISPRCasFinder
CTTCGAAAGAAAAGACCTTTTCGGTTTCTATATCTGAATCTCCC
>6.22|827735|38|NZ_CP021983|CRISPRCasFinder
CAAAGTATCTACAAACCCAGCGGCGACCGCCCCCGGGC
>6.23|827809|41|NZ_CP021983|CRISPRCasFinder
CAAAGCTTGGGCCAGCTCTAAAGCACTGGCATCAACTTCCC
>6.24|827886|37|NZ_CP021983|CRISPRCasFinder
TGTTCAGGGTGTTCAATGGTAGTTGTTTTAGTTAGCC
>6.25|827959|39|NZ_CP021983|CRISPRCasFinder
GTTAAGTAAAAATTTTATTGAAAGAGTTCTTACCTTAAC
>6.26|828034|36|NZ_CP021983|CRISPRCasFinder
CAAATACATCCAGTCATAGAGGCGATTGTAAGGCAG
>6.27|828106|38|NZ_CP021983|CRISPRCasFinder
TGGCTGCATCGTCGCCTGGTGAAGCTAACGGAGCAAAC
>6.28|828180|43|NZ_CP021983|CRISPRCasFinder
CGGGGTGGTGACTAGCTCGTAGCAAGCAGTCAGCTCCCCGCCC
>6.29|828259|43|NZ_CP021983|CRISPRCasFinder
GGACTTAGGTACAGGGTTGTTTAGATGGACCTATTGGATCGCC
>6.30|828338|36|NZ_CP021983|CRISPRCasFinder
TTTTCCAAGATTTGGCAAATCAGCGGCGTGTCGTTG
>6.31|828410|39|NZ_CP021983|CRISPRCasFinder
AGATGTCACAACAAACCCTGAGGCCGCAGCATACAAGAC
>6.32|828485|39|NZ_CP021983|CRISPRCasFinder
ACTTGTCGGATCAGTAATTTACTGAGATCTCATCGCAGC
>6.33|828560|48|NZ_CP021983|CRISPRCasFinder
TGGGCCGGCGACTTGGTAGAGGTAACGGGGGTCCCTCTTCCTGTTTCC
>6.34|828644|42|NZ_CP021983|CRISPRCasFinder
CCACTGAAAAAGTTAGAGCTGTTATTGTTATAAACGATGGCC
>6.35|828722|42|NZ_CP021983|CRISPRCasFinder
TGTGGATTTAATGCTGCCGGGTCTCGTTATTGTTGTGAATAC
>6.36|828800|51|NZ_CP021983|CRISPRCasFinder
CCGTAATGGCAATTTTGTTATTATCTAGGTAATGAGAAAATTCTTTCATAG
>6.37|828887|41|NZ_CP021983|CRISPRCasFinder
CAACTCTTGGGGATCGAGGAGTACGGAAAATGCTTCATCCC
>6.38|828964|42|NZ_CP021983|CRISPRCasFinder
TCGTTGCCGATATGCAATCGCAGCGGGCAGCTCTTCTCCGTC
>6.39|829042|37|NZ_CP021983|CRISPRCasFinder
GGTGTAGCCAGGATTAGAAGGGTGGTCATTGGTCAAG
>6.40|829115|41|NZ_CP021983|CRISPRCasFinder
TCACGTCAACCCATAAGATCGTGTCCACAGATCCATTCGCC
>6.41|829192|44|NZ_CP021983|CRISPRCasFinder
CCCAGACAGTTGTGCTTTTTGACGCTAACCGTGCCAGCCCTGGC
>6.42|829272|40|NZ_CP021983|CRISPRCasFinder
CGACTTCCCCCAGCGGGACGCCACAGCCTCTTGAGCTGTG
>6.43|829348|41|NZ_CP021983|CRISPRCasFinder
CTATGCCTTCTTCAGTTATGGCGACGCCATGTTCCTGACCC
>6.44|829425|37|NZ_CP021983|CRISPRCasFinder
TACTTCCTCTAGTTCAACATATCCCGATGTAACCAAC
>6.45|829498|43|NZ_CP021983|CRISPRCasFinder
CCTCGCGCATCCACAGTAGGCTTTAGCAAATTTACCTCGATTG
>6.46|829577|46|NZ_CP021983|CRISPRCasFinder
AACATAAAAATTTGTTTTAGTTCTTACACGCCTCAGTTTCATGCAC
>6.47|829659|37|NZ_CP021983|CRISPRCasFinder
ACTGAAGCCTGTCGGGTGGCCCAGCGCATCCACATGC
>6.48|829732|40|NZ_CP021983|CRISPRCasFinder
CGAGAGGCAGGACCAGCGATTGCAGCAGCAGGAAGAGGAA
>6.49|829808|33|NZ_CP021983|CRISPRCasFinder
ACGTATGGCCGGCCAGCAGGTTCTATGTCTATA
>6.50|829877|39|NZ_CP021983|CRISPRCasFinder
GATCTCAAGTCGAGAGATCTTCAACAAATACCAAACTAG
>6.51|829952|38|NZ_CP021983|CRISPRCasFinder
CCACAGTCCCTAGGGGTTGAGGACGGAGCAGGTTTTCC
>6.52|830026|40|NZ_CP021983|CRISPRCasFinder
ATGACTGACGCCCGGGACTCACCCGAATCCCGCAAACGAG
>6.53|830102|40|NZ_CP021983|CRISPRCasFinder
CCGAACAATAACTGTCAGGTCACCAAAGTCAATGTTGTAG
>6.54|830178|38|NZ_CP021983|CRISPRCasFinder
CAAGGCTATCGATTAAAATGCGCTCGATTTTACCCGCA
>6.55|830252|39|NZ_CP021983|CRISPRCasFinder
AACTTTGAGTCCACCAGGATACCATAACAGGAGCACTAG
>6.56|830327|44|NZ_CP021983|CRISPRCasFinder
CCAGTTCTTTTTATAAAAAAGTTCTCACACCATAAGAGAAAGTT
>6.57|830407|34|NZ_CP021983|CRISPRCasFinder
GTGGTAGGAAAAGTCGCAGCAAATGGCGCGGCAC
>6.58|830477|44|NZ_CP021983|CRISPRCasFinder
GTCTCCGGGTTTGTAGGGTTTTTCCTTCCTGTTATCTATATCCC
>6.59|830557|38|NZ_CP021983|CRISPRCasFinder
TACAAGCAGCGGCTTCATTTGCAAGTTTACTGACTTCA
>6.60|830631|44|NZ_CP021983|CRISPRCasFinder
CATCATTCCATAGTCGATCTGGTCAACTGCCCATTAGGTTAGGC
>6.61|830711|39|NZ_CP021983|CRISPRCasFinder
ATGAATTCCTGCTAAGTCAAGATTTGGTAGTTCCGACAG
>6.62|830786|42|NZ_CP021983|CRISPRCasFinder
CAAACGATCGAAGTTGCTGATATTTCAGCGTTGAAAGCGCTC
>6.63|830864|45|NZ_CP021983|CRISPRCasFinder
CGGTCGTGATTGGTCGCTACGCGGCTGAGGGTGCTCTTTACCCTA
>6.64|826108|36|NZ_CP021983|CRT
CCGCTTGAACACCCGGATCAGTATCCGCAGCGATCG
>6.65|826178|45|NZ_CP021983|CRT
CTCACAGTCCTCGCTGAATTCGCTTCATTTTGAGCCACTCACCAA
>6.66|826257|50|NZ_CP021983|CRT
CTCAGGGAACAAATTGATTTTGCCGTTCACCCAAATTGCGGCATAGATTA
>6.67|826341|41|NZ_CP021983|CRT
CTCTTTATGCTCTGGTCTGTAGAGCTCTGGATTCAGCATCC
>6.68|826416|40|NZ_CP021983|CRT
CTGATTAAGTTCGGGAACACAACCATCTGCAGTGTTATGC
>6.69|826490|43|NZ_CP021983|CRT
CCCTCGATGTCCTTGAAGTTTTATAGGCTCTTTAGTATCCGCC
>6.70|826567|41|NZ_CP021983|CRT
CCTTCTGCTAAGAAAGGATCCATCGTCAAACACGATAAACC
>6.71|826642|42|NZ_CP021983|CRT
CGCTGACGTAGCGCAAACCATTCTTCAGCCAGGAAGCTTGGC
>6.72|826718|46|NZ_CP021983|CRT
CCCGTAGGCCCCATTTGCAACTGCGCGAATACAGGATTCCGTGCCC
>6.73|826798|45|NZ_CP021983|CRT
CAGCAAGGGTTTCAGCCATTCCTCTCCCTTTGCTATACTCTTCCC
>6.74|826877|45|NZ_CP021983|CRT
CTCGGGTATCAGTGCTGCTCCTAGTGCCTTAACCCCAACTCAACC
>6.75|826956|43|NZ_CP021983|CRT
CTTTGGAAAGTAGTTTATATAAATTTAGATGACTCCGAAAGCC
>6.76|827033|43|NZ_CP021983|CRT
CTAAATACGGGTGGACCTTCAAAGATTTTGATTCTGTTGACCC
>6.77|827110|42|NZ_CP021983|CRT
CTTATTCGAACCACTTGGATAAAGTCAACGAACAATTGACCC
>6.78|827186|47|NZ_CP021983|CRT
ACGCGGGGAGCAGTCAACAGGTTGGTGAGTTTCTCATGTATGTTGCC
>6.79|827267|50|NZ_CP021983|CRT
CCGTAACAGAGGTGGTCTAAGCTCTAAAACCCTTGCTGTGTAGGAGTTCC
>6.80|827351|41|NZ_CP021983|CRT
ACAGTTCCTCCAAAAGATGTTTCTCAGAGTGTGGCGACCCC
>6.81|827426|40|NZ_CP021983|CRT
CAATAATCAGTATAAAACTGCCCATTCGTAATACAAACAC
>6.82|827500|46|NZ_CP021983|CRT
AACCTAGTAATCCCCTGTTTGTTTTTGTAAGGGTAAGGCCGGTTGC
>6.83|827580|40|NZ_CP021983|CRT
CGAAGGACGCATTATTGATCTTACTGGCGCAACCAACCCC
>6.84|827654|46|NZ_CP021983|CRT
CCTTCGAAAGAAAAGACCTTTTCGGTTTCTATATCTGAATCTCCCC
>6.85|827734|40|NZ_CP021983|CRT
ACAAAGTATCTACAAACCCAGCGGCGACCGCCCCCGGGCC
>6.86|827808|43|NZ_CP021983|CRT
ACAAAGCTTGGGCCAGCTCTAAAGCACTGGCATCAACTTCCCC
>6.87|827885|39|NZ_CP021983|CRT
CTGTTCAGGGTGTTCAATGGTAGTTGTTTTAGTTAGCCC
>6.88|827958|41|NZ_CP021983|CRT
CGTTAAGTAAAAATTTTATTGAAAGAGTTCTTACCTTAACC
>6.89|828033|38|NZ_CP021983|CRT
CCAAATACATCCAGTCATAGAGGCGATTGTAAGGCAGC
>6.90|828105|40|NZ_CP021983|CRT
CTGGCTGCATCGTCGCCTGGTGAAGCTAACGGAGCAAACC
>6.91|828179|45|NZ_CP021983|CRT
ACGGGGTGGTGACTAGCTCGTAGCAAGCAGTCAGCTCCCCGCCCC
>6.92|828258|45|NZ_CP021983|CRT
CGGACTTAGGTACAGGGTTGTTTAGATGGACCTATTGGATCGCCC
>6.93|828337|38|NZ_CP021983|CRT
CTTTTCCAAGATTTGGCAAATCAGCGGCGTGTCGTTGC
>6.94|828409|41|NZ_CP021983|CRT
CAGATGTCACAACAAACCCTGAGGCCGCAGCATACAAGACC
>6.95|828484|41|NZ_CP021983|CRT
CACTTGTCGGATCAGTAATTTACTGAGATCTCATCGCAGCC
>6.96|828559|50|NZ_CP021983|CRT
CTGGGCCGGCGACTTGGTAGAGGTAACGGGGGTCCCTCTTCCTGTTTCCC
>6.97|828643|44|NZ_CP021983|CRT
CCCACTGAAAAAGTTAGAGCTGTTATTGTTATAAACGATGGCCC
>6.98|828721|44|NZ_CP021983|CRT
CTGTGGATTTAATGCTGCCGGGTCTCGTTATTGTTGTGAATACC
>6.99|828799|53|NZ_CP021983|CRT
CCCGTAATGGCAATTTTGTTATTATCTAGGTAATGAGAAAATTCTTTCATAGC
>6.100|828886|43|NZ_CP021983|CRT
ACAACTCTTGGGGATCGAGGAGTACGGAAAATGCTTCATCCCC
>6.101|828963|44|NZ_CP021983|CRT
CTCGTTGCCGATATGCAATCGCAGCGGGCAGCTCTTCTCCGTCC
>6.102|829041|39|NZ_CP021983|CRT
CGGTGTAGCCAGGATTAGAAGGGTGGTCATTGGTCAAGC
>6.103|829114|42|NZ_CP021983|CRT
CTCACGTCAACCCATAAGATCGTGTCCACAGATCCATTCGCC
>6.104|829190|46|NZ_CP021983|CRT
AACCCAGACAGTTGTGCTTTTTGACGCTAACCGTGCCAGCCCTGGC
>6.105|829270|42|NZ_CP021983|CRT
AACGACTTCCCCCAGCGGGACGCCACAGCCTCTTGAGCTGTG
>6.106|829346|43|NZ_CP021983|CRT
ACCTATGCCTTCTTCAGTTATGGCGACGCCATGTTCCTGACCC
>6.107|829423|39|NZ_CP021983|CRT
ACTACTTCCTCTAGTTCAACATATCCCGATGTAACCAAC
>6.108|829496|46|NZ_CP021983|CRT
ACCCTCGCGCATCCACAGTAGGCTTTAGCAAATTTACCTCGATTGC
>6.109|829576|47|NZ_CP021983|CRT
CAACATAAAAATTTGTTTTAGTTCTTACACGCCTCAGTTTCATGCAC
>6.110|829657|39|NZ_CP021983|CRT
ACACTGAAGCCTGTCGGGTGGCCCAGCGCATCCACATGC
>6.111|829730|42|NZ_CP021983|CRT
ACCGAGAGGCAGGACCAGCGATTGCAGCAGCAGGAAGAGGAA
>6.112|829806|35|NZ_CP021983|CRT
ACACGTATGGCCGGCCAGCAGGTTCTATGTCTATA
>6.113|829875|41|NZ_CP021983|CRT
AAGATCTCAAGTCGAGAGATCTTCAACAAATACCAAACTAG
>6.114|829950|40|NZ_CP021983|CRT
ACCCACAGTCCCTAGGGGTTGAGGACGGAGCAGGTTTTCC
>6.115|830024|42|NZ_CP021983|CRT
ACATGACTGACGCCCGGGACTCACCCGAATCCCGCAAACGAG
>6.116|830100|42|NZ_CP021983|CRT
ACCCGAACAATAACTGTCAGGTCACCAAAGTCAATGTTGTAG
>6.117|830176|40|NZ_CP021983|CRT
CTCAAGGCTATCGATTAAAATGCGCTCGATTTTACCCGCA
>6.118|830250|40|NZ_CP021983|CRT
ACAACTTTGAGTCCACCAGGATACCATAACAGGAGCACTA
>6.119|830324|46|NZ_CP021983|CRT
AAACCAGTTCTTTTTATAAAAAAGTTCTCACACCATAAGAGAAAGT
>6.120|830404|37|NZ_CP021983|CRT
AACGTGGTAGGAAAAGTCGCAGCAAATGGCGCGGCAC
>6.121|830475|45|NZ_CP021983|CRT
ACGTCTCCGGGTTTGTAGGGTTTTTCCTTCCTGTTATCTATATCC
>6.122|830554|40|NZ_CP021983|CRT
ACGTACAAGCAGCGGCTTCATTTGCAAGTTTACTGACTTC
>6.123|830628|46|NZ_CP021983|CRT
ACGCATCATTCCATAGTCGATCTGGTCAACTGCCCATTAGGTTAGG
>6.124|830708|42|NZ_CP021983|CRT
AACATGAATTCCTGCTAAGTCAAGATTTGGTAGTTCCGACAG
>6.125|830784|43|NZ_CP021983|CRT
ACCAAACGATCGAAGTTGCTGATATTTCAGCGTTGAAAGCGCT
>6.126|830861|47|NZ_CP021983|CRT
AAACGGTCGTGATTGGTCGCTACGCGGCTGAGGGTGCTCTTTACCCT
>6.127|830942|40|NZ_CP021983|CRT
AACATAGGCAAAGGAGAGATCAACCCAAAGAGGACGTCGA
>6.128|831016|43|NZ_CP021983|CRT
AAACTCAGCCCGCGACGAGCGAGCGAGGAGCACTATGCGCAGT
>6.129|831093|43|NZ_CP021983|CRT
AACCGGTTGATGCCGCCATGGAAGGCGGTACCATAGTTTCGTT
>6.130|831170|43|NZ_CP021983|CRT
AACTCACCTGAATAGTACCCAGAGATTGTGCCTGATTCAGTCC
>6.131|831247|42|NZ_CP021983|CRT
AACACCTGGCATCGACACCTGGCCTGTCACTACAACAACTGG
>6.132|831323|43|NZ_CP021983|CRT
AACTCTAAAAACTGACCCTTCCGTCATCGCCAGCGTTTCACCT
>6.133|831400|40|NZ_CP021983|CRT
AACTGAAAATCCAGAATCATGAGGACACTAAGCAACTTGT
>6.134|831474|45|NZ_CP021983|CRT
AACGACTGGCGTTTCCCAATGGGCCGAGCATTTTCATGCCGGTTC
>6.135|831553|42|NZ_CP021983|CRT
AACGGGAAGTTCCTCAAAAGTACTATATGGATTTGACTCAAG
>6.136|831629|41|NZ_CP021983|CRT
AACCAAAATCCCCGGTATTCTTCTTCTTGGATGTGAACTTC
>6.137|831704|42|NZ_CP021983|CRT
AACGCCCTCTCCCGTTGGGGTTGGCGCATGATATATCTTGGC
>6.138|831780|43|NZ_CP021983|CRT
AACATGGGGGAGCTAGGCCAGGAGCCGGTCGAAAACCTAAATA
>6.139|831857|40|NZ_CP021983|CRT
AACGTCAGTAACTGAAGCTTTGATTGAATCCCCCTTGTTA
>6.140|831931|45|NZ_CP021983|CRT
AACGATTGTTAATTGGAGTAGAGAGTCCACTTTCTGCGGTTTGCA
>6.141|826169|60|NZ_CP021983|PILER-CR
TAGTTGGAAACTCACAGTCCTCGCTGAATTCGCTTCATTTTGAGCCACTCACCAACCCAC
>6.142|826249|65|NZ_CP021983|PILER-CR
TAGTTGGAAACTCAGGGAACAAATTGATTTTGCCGTTCACCCAAATTGCGGCATAGATTACCCAC
>6.143|826334|56|NZ_CP021983|PILER-CR
TAGTTGGAAACTCTTTATGCTCTGGTCTGTAGAGCTCTGGATTCAGCATCCCCCAC
>6.144|826410|55|NZ_CP021983|PILER-CR
TAGTTGGAAACTGATTAAGTTCGGGAACACAACCATCTGCAGTGTTATGCCCCAC
>6.145|826485|58|NZ_CP021983|PILER-CR
TAGTTGGAAACCCTCGATGTCCTTGAAGTTTTATAGGCTCTTTAGTATCCGCCCCCAC
>6.146|826563|56|NZ_CP021983|PILER-CR
TAGTTGGAAACCTTCTGCTAAGAAAGGATCCATCGTCAAACACGATAAACCCCCAC
>6.147|826639|57|NZ_CP021983|PILER-CR
TAGTTGGAAACGCTGACGTAGCGCAAACCATTCTTCAGCCAGGAAGCTTGGCCCCAC
>6.148|826716|61|NZ_CP021983|PILER-CR
TAGTTGGAAACCCGTAGGCCCCATTTGCAACTGCGCGAATACAGGATTCCGTGCCCCCCAC
>6.149|826797|60|NZ_CP021983|PILER-CR
TAGTTGGAAACAGCAAGGGTTTCAGCCATTCCTCTCCCTTTGCTATACTCTTCCCCCCAC
>6.150|826877|60|NZ_CP021983|PILER-CR
TAGTTGGAAACTCGGGTATCAGTGCTGCTCCTAGTGCCTTAACCCCAACTCAACCCCCAC
>6.151|826957|58|NZ_CP021983|PILER-CR
TAGTTGGAAACTTTGGAAAGTAGTTTATATAAATTTAGATGACTCCGAAAGCCCCCAC
>6.152|827035|58|NZ_CP021983|PILER-CR
TAGTTGGAAACTAAATACGGGTGGACCTTCAAAGATTTTGATTCTGTTGACCCCCCAC
>6.153|827113|63|NZ_CP021983|PILER-CR
TAGTTGGAAACTTATTCGAACCACTTGGATAAAGTCAACGAACAATTGACCCCCCACCGATTG
>6.154|827196|61|NZ_CP021983|PILER-CR
TAGTTGGAAACGCGGGGAGCAGTCAACAGGTTGGTGAGTTTCTCATGTATGTTGCCCCCAC
>6.155|827277|65|NZ_CP021983|PILER-CR
TAGTTGGAAACCGTAACAGAGGTGGTCTAAGCTCTAAAACCCTTGCTGTGTAGGAGTTCCCCCAC
>6.156|827362|55|NZ_CP021983|PILER-CR
TAGTTGGAAACAGTTCCTCCAAAAGATGTTTCTCAGAGTGTGGCGACCCCCCCAC
>6.157|827437|61|NZ_CP021983|PILER-CR
TAGTTGGAAACAATAATCAGTATAAAACTGCCCATTCGTAATACAAACACCCCACCGATTG
>6.158|827518|60|NZ_CP021983|PILER-CR
TAGTTTGGAAACCTAGTAATCCCCTGTTTGTTTTTGTAAGGGTAAGGCCGGTTGCCCCAC
>6.159|827598|55|NZ_CP021983|PILER-CR
TAGTTGGAAACGAAGGACGCATTATTGATCTTACTGGCGCAACCAACCCCCACAC
>6.160|827673|61|NZ_CP021983|PILER-CR
TAGTTGGAAACCTTCGAAAGAAAAGACCTTTTCGGTTTCTATATCTGAATCTCCCCCCACC
>6.161|827754|55|NZ_CP021983|PILER-CR
TAGTTTGGAAACAAAGTATCTACAAACCCAGCGGCGACCGCCCCCGGGCCCCCAC
>6.162|827829|58|NZ_CP021983|PILER-CR
TAGTTGGGAAACAAAGCTTGGGCCAGCTCTAAAGCACTGGCATCAACTTCCCCCCACC
>6.163|827907|59|NZ_CP021983|PILER-CR
TAGTTGGAAACTGTTCAGGGTGTTCAATGGTAGTTGTTTTAGTTAGCCCCCACCGATTG
>6.164|827986|56|NZ_CP021983|PILER-CR
TAGTTGGAAACGTTAAGTAAAAATTTTATTGAAAGAGTTCTTACCTTAACCCCCAC
>6.165|828062|59|NZ_CP021983|PILER-CR
TAGTTGGAAACCAAATACATCCAGTCATAGAGGCGATTGTAAGGCAGCCCCCACCGATT
>6.166|828141|55|NZ_CP021983|PILER-CR
TAGTTGGAAACTGGCTGCATCGTCGCCTGGTGAAGCTAACGGAGCAAACCCCCAC
>6.167|828216|60|NZ_CP021983|PILER-CR
ATAGTTGGAAACGGGGTGGTGACTAGCTCGTAGCAAGCAGTCAGCTCCCCGCCCCCCCAC
>6.168|828296|60|NZ_CP021983|PILER-CR
TAGTTGGAAACGGACTTAGGTACAGGGTTGTTTAGATGGACCTATTGGATCGCCCCCCAC
>6.169|828376|53|NZ_CP021983|PILER-CR
TAGTTGGAAACTTTTCCAAGATTTGGCAAATCAGCGGCGTGTCGTTGCCCCAC
>6.170|828449|56|NZ_CP021983|PILER-CR
TAGTTGGAAACAGATGTCACAACAAACCCTGAGGCCGCAGCATACAAGACCCCCAC
>6.171|828525|56|NZ_CP021983|PILER-CR
TAGTTGGAAACACTTGTCGGATCAGTAATTTACTGAGATCTCATCGCAGCCCCCAC
>6.172|828601|70|NZ_CP021983|PILER-CR
TAGTTGGAAACTGGGCCGGCGACTTGGTAGAGGTAACGGGGGTCCCTCTTCCTGTTTCCCCCACCGATTG
>6.173|828691|58|NZ_CP021983|PILER-CR
TAGTTGGAAACCCACTGAAAAAGTTAGAGCTGTTATTGTTATAAACGATGGCCCCCAC
>6.174|828769|59|NZ_CP021983|PILER-CR
TAGTTGGAAACTGTGGATTTAATGCTGCCGGGTCTCGTTATTGTTGTGAATACCCCCAC
>6.175|828848|68|NZ_CP021983|PILER-CR
TAGTTGGAAACCCGTAATGGCAATTTTGTTATTATCTAGGTAATGAGAAAATTCTTTCATAGCCCCAC
>6.176|828936|58|NZ_CP021983|PILER-CR
TAGTTGGAAAACAACTCTTGGGGATCGAGGAGTACGGAAAATGCTTCATCCCCCCCAC
>6.177|829014|59|NZ_CP021983|PILER-CR
TAGTTGGAAACTCGTTGCCGATATGCAATCGCAGCGGGCAGCTCTTCTCCGTCCCCCAC
>6.178|829093|55|NZ_CP021983|PILER-CR
TAGTTGGAAACGGTGTAGCCAGGATTAGAAGGGTGGTCATTGGTCAAGCCCCCAC
>6.179|829168|58|NZ_CP021983|PILER-CR
TAGTTGGAAACTCACGTCAACCCATAAGATCGTGTCCACAGATCCATTCGCCCCCCAC
>6.180|829246|61|NZ_CP021983|PILER-CR
ATAGTTGGAAACCCAGACAGTTGTGCTTTTTGACGCTAACCGTGCCAGCCCTGGCCCCCAC
>6.181|829327|57|NZ_CP021983|PILER-CR
TAGGTTGGAAACGACTTCCCCCAGCGGGACGCCACAGCCTCTTGAGCTGTGCCCCCA
>6.182|829404|58|NZ_CP021983|PILER-CR
TAGTTGGAAACCTATGCCTTCTTCAGTTATGGCGACGCCATGTTCCTGACCCCCCCAC
>6.183|829482|54|NZ_CP021983|PILER-CR
TAGTTGGAAACTACTTCCTCTAGTTCAACATATCCCGATGTAACCAACCCCCAC
>6.184|829556|61|NZ_CP021983|PILER-CR
TAGTTGGAAACCCTCGCGCATCCACAGTAGGCTTTAGCAAATTTACCTCGATTGCCCCCAC
>6.185|829637|65|NZ_CP021983|PILER-CR
AATAGTTGGAAACAACATAAAAATTTGTTTTAGTTCTTACACGCCTCAGTTTCATGCACCCCCAC
>6.186|829722|54|NZ_CP021983|PILER-CR
TAGTTGGAAACACTGAAGCCTGTCGGGTGGCCCAGCGCATCCACATGCCCCCAC
>6.187|829796|57|NZ_CP021983|PILER-CR
TAGTTGGAAACCGAGAGGCAGGACCAGCGATTGCAGCAGCAGGAAGAGGAACCCCAC
>6.188|829873|50|NZ_CP021983|PILER-CR
TAGTTGGAAACACGTATGGCCGGCCAGCAGGTTCTATGTCTATACCCCAC
>6.189|829943|56|NZ_CP021983|PILER-CR
TAGTTGAACAAGATCTCAAGTCGAGAGATCTTCAACAAATACCAAACTAGCCCCAC
>6.190|830019|55|NZ_CP021983|PILER-CR
TAGTTGGAAACCCACAGTCCCTAGGGGTTGAGGACGGAGCAGGTTTTCCCCCCAC
>6.191|830094|57|NZ_CP021983|PILER-CR
TAGTTGGAAACATGACTGACGCCCGGGACTCACCCGAATCCCGCAAACGAGCCCCAC
>6.192|830171|57|NZ_CP021983|PILER-CR
TAGTTGGAAACCCGAACAATAACTGTCAGGTCACCAAAGTCAATGTTGTAGCCCCAC
>6.193|830248|56|NZ_CP021983|PILER-CR
TAGTTGGAACTCAAGGCTATCGATTAAAATGCGCTCGATTTTACCCGCAGCCCCAC
>6.194|830324|56|NZ_CP021983|PILER-CR
TAGTTGGAAACAACTTTGAGTCCACCAGGATACCATAACAGGAGCACTAGGCCCAC
>6.195|830400|61|NZ_CP021983|PILER-CR
ATAGTTGGAAACCAGTTCTTTTTATAAAAAAGTTCTCACACCATAAGAGAAAGTTCCCCAC
>6.196|830481|51|NZ_CP021983|PILER-CR
TAGTTGGAAACGTGGTAGGAAAAGTCGCAGCAAATGGCGCGGCACCCCCAC
>6.197|830552|60|NZ_CP021983|PILER-CR
TAGTTGAAACGTCTCCGGGTTTGTAGGGTTTTTCCTTCCTGTTATCTATATCCCCCCCAC
>6.198|830632|55|NZ_CP021983|PILER-CR
TAGTTGGAACGTACAAGCAGCGGCTTCATTTGCAAGTTTACTGACTTCACCCCAC
>6.199|830707|61|NZ_CP021983|PILER-CR
AGTTGGAAACGCATCATTCCATAGTCGATCTGGTCAACTGCCCATTAGGTTAGGCACCCAC
>6.200|830788|57|NZ_CP021983|PILER-CR
TAGTTGGAAACATGAATTCCTGCTAAGTCAAGATTTGGTAGTTCCGACAGGCCCCAC
>6.201|830865|64|NZ_CP021983|PILER-CR
CGGAATATTTGGAAACCAAACGATCGAAGTTGCTGATATTTCAGCGTTGAAAGCGCTCCCCCAC
>6.202|830949|66|NZ_CP021983|PILER-CR
CGGAATAGTTGGAAACGGTCGTGATTGGTCGCTACGCGGCTGAGGGTGCTCTTTACCCTACCCCAC
>6.203|831035|60|NZ_CP021983|PILER-CR
TAGTTGGAAACATAGGCAAAGGAGAGATCAACCCAAAGAGGACGTCGACCCCACCGATTG
>6.204|831115|58|NZ_CP021983|PILER-CR
ATAGTTGGAAACTCAGCCCGCGACGAGCGAGCGAGGAGCACTATGCGCAGTACCCCAC
>6.205|831193|58|NZ_CP021983|PILER-CR
TAGTTGGAAACCGGTTGATGCCGCCATGGAAGGCGGTACCATAGTTTCGTTCCCCACC
>6.206|831271|58|NZ_CP021983|PILER-CR
TAGTTGGAAACTCACCTGAATAGTACCCAGAGATTGTGCCTGATTCAGTCCCCCCCAC
>6.207|831349|56|NZ_CP021983|PILER-CR
TAGTTGGAAACACCTGGCATCGACACCTGGCCTGTCACTACAACAACTGGCCCCAC
>6.208|831425|58|NZ_CP021983|PILER-CR
TAGTTGGAAACTCTAAAAACTGACCCTTCCGTCATCGCCAGCGTTTCACCTCCCCCAC
>6.209|831503|55|NZ_CP021983|PILER-CR
TAGTTGGAAACTGAAAATCCAGAATCATGAGGACACTAAGCAACTTGTCCCCACC
>6.210|831578|60|NZ_CP021983|PILER-CR
TAGTTGGAAACGACTGGCGTTTCCCAATGGGCCGAGCATTTTCATGCCGGTTCCCCCCAC
>6.211|831658|57|NZ_CP021983|PILER-CR
TAGTTGGAAACGGGAAGTTCCTCAAAAGTACTATATGGATTTGACTCAAGCCCCCAC
>6.212|831735|56|NZ_CP021983|PILER-CR
TAGTTGGAAACCAAAATCCCCGGTATTCTTCTTCTTGGATGTGAACTTCTCCCCAC
>6.213|831811|57|NZ_CP021983|PILER-CR
TAGTTGGAAACGCCCTCTCCCGTTGGGGTTGGCGCATGATATATCTTGGCACCCCAC
>6.214|831888|58|NZ_CP021983|PILER-CR
TAGTTGGAAACATGGGGGAGCTAGGCCAGGAGCCGGTCGAAAACCTAAATATCCCCAC
>6.215|831966|55|NZ_CP021983|PILER-CR
TAGTTGGAAACGTCAGTAACTGAAGCTTTGATTGAATCCCCCTTGTTAGCCCCAC
>6.216|832041|60|NZ_CP021983|PILER-CR
TAGTTGGAAACGATTGTTAATTGGAGTAGAGAGTCCACTTTCTGCGGTTTGCAACCCCAC
>6.217|831096|41|NZ_CP021983|CRISPRCasFinder
CGGTTGATGCCGCCATGGAAGGCGGTACCATAGTTTCGTTC
>6.218|831173|41|NZ_CP021983|CRISPRCasFinder
TCACCTGAATAGTACCCAGAGATTGTGCCTGATTCAGTCCC
>6.219|831250|40|NZ_CP021983|CRISPRCasFinder
ACCTGGCATCGACACCTGGCCTGTCACTACAACAACTGGC
>6.220|831326|41|NZ_CP021983|CRISPRCasFinder
TCTAAAAACTGACCCTTCCGTCATCGCCAGCGTTTCACCTC
>6.221|831403|38|NZ_CP021983|CRISPRCasFinder
TGAAAATCCAGAATCATGAGGACACTAAGCAACTTGTC
>6.222|831477|43|NZ_CP021983|CRISPRCasFinder
GACTGGCGTTTCCCAATGGGCCGAGCATTTTCATGCCGGTTCC
>6.223|831556|40|NZ_CP021983|CRISPRCasFinder
GGGAAGTTCCTCAAAAGTACTATATGGATTTGACTCAAGC
>6.224|831632|39|NZ_CP021983|CRISPRCasFinder
CAAAATCCCCGGTATTCTTCTTCTTGGATGTGAACTTCT
>6.225|831707|40|NZ_CP021983|CRISPRCasFinder
GCCCTCTCCCGTTGGGGTTGGCGCATGATATATCTTGGCA
>6.226|831783|41|NZ_CP021983|CRISPRCasFinder
ATGGGGGAGCTAGGCCAGGAGCCGGTCGAAAACCTAAATAT
>6.227|831860|38|NZ_CP021983|CRISPRCasFinder
GTCAGTAACTGAAGCTTTGATTGAATCCCCCTTGTTAG
>6.228|831934|43|NZ_CP021983|CRISPRCasFinder
GATTGTTAATTGGAGTAGAGAGTCCACTTTCTGCGGTTTGCAA

CRISPR arrays and Neighbor proteins around NZ_CP021983_6

CRISPR arrays

The CRISPR arrays of NZ_CP021983_6

>merge|NZ_CP021983|6|826073-832012|CRISPRCasFinder,CRT,PILER-CR,CRISPRCasFinder
TCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCGCTTGAACACCCGGATCAGTATCCGCAGCGATCGCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTCACAGTCCTCGCTGAATTCGCTTCATTTTGAGCCACTCACCAACCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTCAGGGAACAAATTGATTTTGCCGTTCACCCAAATTGCGGCATAGATTACCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTCTTTATGCTCTGGTCTGTAGAGCTCTGGATTCAGCATCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTGATTAAGTTCGGGAACACAACCATCTGCAGTGTTATGCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCCTCGATGTCCTTGAAGTTTTATAGGCTCTTTAGTATCCGCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCTTCTGCTAAGAAAGGATCCATCGTCAAACACGATAAACCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGCTGACGTAGCGCAAACCATTCTTCAGCCAGGAAGCTTGGCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCCGTAGGCCCCATTTGCAACTGCGCGAATACAGGATTCCGTGCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACAGCAAGGGTTTCAGCCATTCCTCTCCCTTTGCTATACTCTTCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTCGGGTATCAGTGCTGCTCCTAGTGCCTTAACCCCAACTCAACCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTTTGGAAAGTAGTTTATATAAATTTAGATGACTCCGAAAGCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTAAATACGGGTGGACCTTCAAAGATTTTGATTCTGTTGACCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTTATTCGAACCACTTGGATAAAGTCAACGAACAATTGACCCCCCACCGATTGGGGTTAATTCGGAATAGTTGGAAACGCGGGGAGCAGTCAACAGGTTGGTGAGTTTCTCATGTATGTTGCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCGTAACAGAGGTGGTCTAAGCTCTAAAACCCTTGCTGTGTAGGAGTTCCCCCACCGATTGGGTTTAATTCGGAATAGTTGGAAACAGTTCCTCCAAAAGATGTTTCTCAGAGTGTGGCGACCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACAATAATCAGTATAAAACTGCCCATTCGTAATACAAACACCCCACCGATTGGGGTTAATTCGGAATAGTTTGGAAACCTAGTAATCCCCTGTTTGTTTTTGTAAGGGTAAGGCCGGTTGCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGAAGGACGCATTATTGATCTTACTGGCGCAACCAACCCCCACACCGATTGGGTTAATTCGGAATAGTTGGAAACCTTCGAAAGAAAAGACCTTTTCGGTTTCTATATCTGAATCTCCCCCCACCGAATTGGGTTAATTCGGAATAGTTTGGAAACAAAGTATCTACAAACCCAGCGGCGACCGCCCCCGGGCCCCCACCGATTGGGTTAATTCGGAATAGTTGGGAAACAAAGCTTGGGCCAGCTCTAAAGCACTGGCATCAACTTCCCCCCACCCGATTGGGTTAATTCGGAATAGTTGGAAACTGTTCAGGGTGTTCAATGGTAGTTGTTTTAGTTAGCCCCCACCGATTGGGGTTAATTCGGAATAGTTGGAAACGTTAAGTAAAAATTTTATTGAAAGAGTTCTTACCTTAACCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCAAATACATCCAGTCATAGAGGCGATTGTAAGGCAGCCCCCACCGATTGGTTAATTCGGAATAGTTGGAAACTGGCTGCATCGTCGCCTGGTGAAGCTAACGGAGCAAACCCCCACCGATTGGGTTAATTCGGAAATAGTTGGAAACGGGGTGGTGACTAGCTCGTAGCAAGCAGTCAGCTCCCCGCCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGGACTTAGGTACAGGGTTGTTTAGATGGACCTATTGGATCGCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTTTTCCAAGATTTGGCAAATCAGCGGCGTGTCGTTGCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACAGATGTCACAACAAACCCTGAGGCCGCAGCATACAAGACCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACACTTGTCGGATCAGTAATTTACTGAGATCTCATCGCAGCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTGGGCCGGCGACTTGGTAGAGGTAACGGGGGTCCCTCTTCCTGTTTCCCCCACCGATTGGGGTTAATTCGGAATAGTTGGAAACCCACTGAAAAAGTTAGAGCTGTTATTGTTATAAACGATGGCCCCCACCGATTGGGTTTAATTCGGAATAGTTGGAAACTGTGGATTTAATGCTGCCGGGTCTCGTTATTGTTGTGAATACCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCCGTAATGGCAATTTTGTTATTATCTAGGTAATGAGAAAATTCTTTCATAGCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAACAACTCTTGGGGATCGAGGAGTACGGAAAATGCTTCATCCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTCGTTGCCGATATGCAATCGCAGCGGGCAGCTCTTCTCCGTCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGGTGTAGCCAGGATTAGAAGGGTGGTCATTGGTCAAGCCCCCACCGATTGGGTAATTCGGAATAGTTGGAAACTCACGTCAACCCATAAGATCGTGTCCACAGATCCATTCGCCCCCCACCGATTGGGTTAATTCGGAAATAGTTGGAAACCCAGACAGTTGTGCTTTTTGACGCTAACCGTGCCAGCCCTGGCCCCCACCGATTGGGTTAATTCGGAATAGGTTGGAAACGACTTCCCCCAGCGGGACGCCACAGCCTCTTGAGCTGTGCCCCCACGATTGGGTTAATTCGGAATAGTTGGAAACCTATGCCTTCTTCAGTTATGGCGACGCCATGTTCCTGACCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTACTTCCTCTAGTTCAACATATCCCGATGTAACCAACCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCCTCGCGCATCCACAGTAGGCTTTAGCAAATTTACCTCGATTGCCCCCACCGATTGGGTTAATTCGAATAGTTGGAAACAACATAAAAATTTGTTTTAGTTCTTACACGCCTCAGTTTCATGCACCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACACTGAAGCCTGTCGGGTGGCCCAGCGCATCCACATGCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCGAGAGGCAGGACCAGCGATTGCAGCAGCAGGAAGAGGAACCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACACGTATGGCCGGCCAGCAGGTTCTATGTCTATACCCCACCGATTGGGTTAATTCGGAATAGTTGAACAAGATCTCAAGTCGAGAGATCTTCAACAAATACCAAACTAGCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCCACAGTCCCTAGGGGTTGAGGACGGAGCAGGTTTTCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACATGACTGACGCCCGGGACTCACCCGAATCCCGCAAACGAGCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCCGAACAATAACTGTCAGGTCACCAAAGTCAATGTTGTAGCCCCACCGATTGGGTTAATTCGGAATAGTTGGAACTCAAGGCTATCGATTAAAATGCGCTCGATTTTACCCGCAGCCCCACCGATTGGGTAATTCGGAATAGTTGGAAACAACTTTGAGTCCACCAGGATACCATAACAGGAGCACTAGGCCCACCGATTGGGTTAATTCGGAAATAGTTGGAAACCAGTTCTTTTTATAAAAAAGTTCTCACACCATAAGAGAAAGTTCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGTGGTAGGAAAAGTCGCAGCAAATGGCGCGGCACCCCCACCGATTGGGTTTAATTCGGAATAGTTGAAACGTCTCCGGGTTTGTAGGGTTTTTCCTTCCTGTTATCTATATCCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAACGTACAAGCAGCGGCTTCATTTGCAAGTTTACTGACTTCACCCCACCGATTGGGTTAATTCGGATAGTTGGAAACGCATCATTCCATAGTCGATCTGGTCAACTGCCCATTAGGTTAGGCACCCACCGATTGGGTTAATTCGGAATAGTTGGAAACATGAATTCCTGCTAAGTCAAGATTTGGTAGTTCCGACAGGCCCCACCGATTGGGTTAATCGGAATATTTGGAAACCAAACGATCGAAGTTGCTGATATTTCAGCGTTGAAAGCGCTCCCCCACCGATTGGGTTAATTCCGGAATAGTTGGAAACGGTCGTGATTGGTCGCTACGCGGCTGAGGGTGCTCTTTACCCTACCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACATAGGCAAAGGAGAGATCAACCCAAAGAGGACGTCGACCCCACCGATTGGGGTTAATTCGGAAATAGTTGGAAACTCAGCCCGCGACGAGCGAGCGAGGAGCACTATGCGCAGTACCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCGGTTGATGCCGCCATGGAAGGCGGTACCATAGTTTCGTTCCCCACCCGATTGGGTTTAATCGGAATAGTTGGAAACTCACCTGAATAGTACCCAGAGATTGTGCCTGATTCAGTCCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACACCTGGCATCGACACCTGGCCTGTCACTACAACAACTGGCCCCACCGATTGGGTTTAATTCGGAATAGTTGGAAACTCTAAAAACTGACCCTTCCGTCATCGCCAGCGTTTCACCTCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTGAAAATCCAGAATCATGAGGACACTAAGCAACTTGTCCCCACCCGATTGGGTTAATTCGGAATAGTTGGAAACGACTGGCGTTTCCCAATGGGCCGAGCATTTTCATGCCGGTTCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGGGAAGTTCCTCAAAAGTACTATATGGATTTGACTCAAGCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCAAAATCCCCGGTATTCTTCTTCTTGGATGTGAACTTCTCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGCCCTCTCCCGTTGGGGTTGGCGCATGATATATCTTGGCACCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACATGGGGGAGCTAGGCCAGGAGCCGGTCGAAAACCTAAATATCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGTCAGTAACTGAAGCTTTGATTGAATCCCCCTTGTTAGCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGATTGTTAATTGGAGTAGAGAGTCCACTTTCTGCGGTTTGCAACCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC

>NZ_CP021983|6|6|826073-830945|CRISPRCasFinder
TCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CGCTTGAACACCCGGATCAGTATCCGCAGCGATC
GCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TCACAGTCCTCGCTGAATTCGCTTCATTTTGAGCCACTCACCA
ACCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TCAGGGAACAAATTGATTTTGCCGTTCACCCAAATTGCGGCATAGATT
ACCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TCTTTATGCTCTGGTCTGTAGAGCTCTGGATTCAGCATC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TGATTAAGTTCGGGAACACAACCATCTGCAGTGTTATG
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CCTCGATGTCCTTGAAGTTTTATAGGCTCTTTAGTATCCGC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CTTCTGCTAAGAAAGGATCCATCGTCAAACACGATAAAC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	GCTGACGTAGCGCAAACCATTCTTCAGCCAGGAAGCTTGG
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CCGTAGGCCCCATTTGCAACTGCGCGAATACAGGATTCCGTGCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	AGCAAGGGTTTCAGCCATTCCTCTCCCTTTGCTATACTCTTCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TCGGGTATCAGTGCTGCTCCTAGTGCCTTAACCCCAACTCAAC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TTTGGAAAGTAGTTTATATAAATTTAGATGACTCCGAAAGC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TAAATACGGGTGGACCTTCAAAGATTTTGATTCTGTTGACC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TTATTCGAACCACTTGGATAAAGTCAACGAACAATTGACCC
CCCACCGATTGGGGTTAATTCGGAATAGTTGGAAAC	GCGGGGAGCAGTCAACAGGTTGGTGAGTTTCTCATGTATGTTGC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CGTAACAGAGGTGGTCTAAGCTCTAAAACCCTTGCTGTGTAGGAGTTCC
CCCACCGATTGGGTTTAATTCGGAATAGTTGGAAAC	AGTTCCTCCAAAAGATGTTTCTCAGAGTGTGGCGACCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	AATAATCAGTATAAAACTGCCCATTCGTAATACAAACAC
CCCACCGATTGGGGTTAATTCGGAATAGTTTGGAAA	CCTAGTAATCCCCTGTTTGTTTTTGTAAGGGTAAGGCCGGTTG
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	GAAGGACGCATTATTGATCTTACTGGCGCAACCAACCC
CCACACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CTTCGAAAGAAAAGACCTTTTCGGTTTCTATATCTGAATCTCCC
CCCACCGAATTGGGTTAATTCGGAATAGTTTGGAAA	CAAAGTATCTACAAACCCAGCGGCGACCGCCCCCGGGC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGGAAA	CAAAGCTTGGGCCAGCTCTAAAGCACTGGCATCAACTTCCC
CCCACCCGATTGGGTTAATTCGGAATAGTTGGAAAC	TGTTCAGGGTGTTCAATGGTAGTTGTTTTAGTTAGCC
CCCACCGATTGGGGTTAATTCGGAATAGTTGGAAAC	GTTAAGTAAAAATTTTATTGAAAGAGTTCTTACCTTAAC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CAAATACATCCAGTCATAGAGGCGATTGTAAGGCAG
CCCCCACCGATTGGTTAATTCGGAATAGTTGGAAAC	TGGCTGCATCGTCGCCTGGTGAAGCTAACGGAGCAAAC
CCCCACCGATTGGGTTAATTCGGAAATAGTTGGAAA	CGGGGTGGTGACTAGCTCGTAGCAAGCAGTCAGCTCCCCGCCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	GGACTTAGGTACAGGGTTGTTTAGATGGACCTATTGGATCGCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TTTTCCAAGATTTGGCAAATCAGCGGCGTGTCGTTG
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	AGATGTCACAACAAACCCTGAGGCCGCAGCATACAAGAC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	ACTTGTCGGATCAGTAATTTACTGAGATCTCATCGCAGC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TGGGCCGGCGACTTGGTAGAGGTAACGGGGGTCCCTCTTCCTGTTTCC
CCCACCGATTGGGGTTAATTCGGAATAGTTGGAAAC	CCACTGAAAAAGTTAGAGCTGTTATTGTTATAAACGATGGCC
CCCACCGATTGGGTTTAATTCGGAATAGTTGGAAAC	TGTGGATTTAATGCTGCCGGGTCTCGTTATTGTTGTGAATAC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CCGTAATGGCAATTTTGTTATTATCTAGGTAATGAGAAAATTCTTTCATAG
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAA	CAACTCTTGGGGATCGAGGAGTACGGAAAATGCTTCATCCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TCGTTGCCGATATGCAATCGCAGCGGGCAGCTCTTCTCCGTC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	GGTGTAGCCAGGATTAGAAGGGTGGTCATTGGTCAAG
CCCCCACCGATTGGGTAATTCGGAATAGTTGGAAAC	TCACGTCAACCCATAAGATCGTGTCCACAGATCCATTCGCC
CCCCACCGATTGGGTTAATTCGGAAATAGTTGGAAA	CCCAGACAGTTGTGCTTTTTGACGCTAACCGTGCCAGCCCTGGC
CCCCACCGATTGGGTTAATTCGGAATAGGTTGGAAA	CGACTTCCCCCAGCGGGACGCCACAGCCTCTTGAGCTGTG
CCCCCACGATTGGGTTAATTCGGAATAGTTGGAAAC	CTATGCCTTCTTCAGTTATGGCGACGCCATGTTCCTGACCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TACTTCCTCTAGTTCAACATATCCCGATGTAACCAAC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CCTCGCGCATCCACAGTAGGCTTTAGCAAATTTACCTCGATTG
CCCCCACCGATTGGGTTAATTCGAATAGTTGGAAAC	AACATAAAAATTTGTTTTAGTTCTTACACGCCTCAGTTTCATGCAC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	ACTGAAGCCTGTCGGGTGGCCCAGCGCATCCACATGC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CGAGAGGCAGGACCAGCGATTGCAGCAGCAGGAAGAGGAA
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	ACGTATGGCCGGCCAGCAGGTTCTATGTCTATA
CCCCACCGATTGGGTTAATTCGGAATAGTTGAACAA	GATCTCAAGTCGAGAGATCTTCAACAAATACCAAACTAG
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CCACAGTCCCTAGGGGTTGAGGACGGAGCAGGTTTTCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	ATGACTGACGCCCGGGACTCACCCGAATCCCGCAAACGAG
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CCGAACAATAACTGTCAGGTCACCAAAGTCAATGTTGTAG
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAACT	CAAGGCTATCGATTAAAATGCGCTCGATTTTACCCGCA
GCCCCACCGATTGGGTAATTCGGAATAGTTGGAAAC	AACTTTGAGTCCACCAGGATACCATAACAGGAGCACTAG
GCCCACCGATTGGGTTAATTCGGAAATAGTTGGAAA	CCAGTTCTTTTTATAAAAAAGTTCTCACACCATAAGAGAAAGTT
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	GTGGTAGGAAAAGTCGCAGCAAATGGCGCGGCAC
CCCCACCGATTGGGTTTAATTCGGAATAGTTGAAAC	GTCTCCGGGTTTGTAGGGTTTTTCCTTCCTGTTATCTATATCCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAACG	TACAAGCAGCGGCTTCATTTGCAAGTTTACTGACTTCA
CCCCACCGATTGGGTTAATTCGGATAGTTGGAAACG	CATCATTCCATAGTCGATCTGGTCAACTGCCCATTAGGTTAGGC
ACCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	ATGAATTCCTGCTAAGTCAAGATTTGGTAGTTCCGACAG
GCCCCACCGATTGGGTTAATCGGAATATTTGGAAAC	CAAACGATCGAAGTTGCTGATATTTCAGCGTTGAAAGCGCTC
CCCCACCGATTGGGTTAATTCCGGAATAGTTGGAAA	CGGTCGTGATTGGTCGCTACGCGGCTGAGGGTGCTCTTTACCCTA
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACATAGGCAAAGGAGAGATCAACCCAAAGAGGACGTCGACCCCACCGATTGGGGTTAATTCGGAAATAGTTGGAAACTCAGCCCGCGACGAGCGAGCGAGGAGCACTATGCGCAGTACCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CGGTTGATGCCGCCATGGAAGGCGGTACCATAGTTTCGTTC
CCCACCCGATTGGGTTTAATCGGAATAGTTGGAAAC	TCACCTGAATAGTACCCAGAGATTGTGCCTGATTCAGTCCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	ACCTGGCATCGACACCTGGCCTGTCACTACAACAACTGGC
CCCACCGATTGGGTTTAATTCGGAATAGTTGGAAAC	TCTAAAAACTGACCCTTCCGTCATCGCCAGCGTTTCACCTC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TGAAAATCCAGAATCATGAGGACACTAAGCAACTTGTC
CCCACCCGATTGGGTTAATTCGGAATAGTTGGAAAC	GACTGGCGTTTCCCAATGGGCCGAGCATTTTCATGCCGGTTCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	GGGAAGTTCCTCAAAAGTACTATATGGATTTGACTCAAGC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CAAAATCCCCGGTATTCTTCTTCTTGGATGTGAACTTCT
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	GCCCTCTCCCGTTGGGGTTGGCGCATGATATATCTTGGCA
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	ATGGGGGAGCTAGGCCAGGAGCCGGTCGAAAACCTAAATAT
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	GTCAGTAACTGAAGCTTTGATTGAATCCCCCTTGTTAG
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	GATTGTTAATTGGAGTAGAGAGTCCACTTTCTGCGGTTTGCAA


>NZ_CP021983|6|3|826074-832009|CRT
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CCGCTTGAACACCCGGATCAGTATCCGCAGCGATCG
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CTCACAGTCCTCGCTGAATTCGCTTCATTTTGAGCCACTCACCAA
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CTCAGGGAACAAATTGATTTTGCCGTTCACCCAAATTGCGGCATAGATTA
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CTCTTTATGCTCTGGTCTGTAGAGCTCTGGATTCAGCATCC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CTGATTAAGTTCGGGAACACAACCATCTGCAGTGTTATGC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CCCTCGATGTCCTTGAAGTTTTATAGGCTCTTTAGTATCCGCC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CCTTCTGCTAAGAAAGGATCCATCGTCAAACACGATAAACC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CGCTGACGTAGCGCAAACCATTCTTCAGCCAGGAAGCTTGGC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CCCGTAGGCCCCATTTGCAACTGCGCGAATACAGGATTCCGTGCCC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CAGCAAGGGTTTCAGCCATTCCTCTCCCTTTGCTATACTCTTCCC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CTCGGGTATCAGTGCTGCTCCTAGTGCCTTAACCCCAACTCAACC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CTTTGGAAAGTAGTTTATATAAATTTAGATGACTCCGAAAGCC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CTAAATACGGGTGGACCTTCAAAGATTTTGATTCTGTTGACCC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CTTATTCGAACCACTTGGATAAAGTCAACGAACAATTGACCC
CCCACCGATTGGGGTTAATTCGGAATAGTTGGAA	ACGCGGGGAGCAGTCAACAGGTTGGTGAGTTTCTCATGTATGTTGCC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CCGTAACAGAGGTGGTCTAAGCTCTAAAACCCTTGCTGTGTAGGAGTTCC
CCCACCGATTGGGTTTAATTCGGAATAGTTGGAA	ACAGTTCCTCCAAAAGATGTTTCTCAGAGTGTGGCGACCCC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CAATAATCAGTATAAAACTGCCCATTCGTAATACAAACAC
CCCACCGATTGGGGTTAATTCGGAATAGTTTGGA	AACCTAGTAATCCCCTGTTTGTTTTTGTAAGGGTAAGGCCGGTTGC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CGAAGGACGCATTATTGATCTTACTGGCGCAACCAACCCC
CACACCGATTGGGTTAATTCGGAATAGTTGGAAA	CCTTCGAAAGAAAAGACCTTTTCGGTTTCTATATCTGAATCTCCCC
CCACCGAATTGGGTTAATTCGGAATAGTTTGGAA	ACAAAGTATCTACAAACCCAGCGGCGACCGCCCCCGGGCC
CCCACCGATTGGGTTAATTCGGAATAGTTGGGAA	ACAAAGCTTGGGCCAGCTCTAAAGCACTGGCATCAACTTCCCC
CCACCCGATTGGGTTAATTCGGAATAGTTGGAAA	CTGTTCAGGGTGTTCAATGGTAGTTGTTTTAGTTAGCCC
CCACCGATTGGGGTTAATTCGGAATAGTTGGAAA	CGTTAAGTAAAAATTTTATTGAAAGAGTTCTTACCTTAACC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CCAAATACATCCAGTCATAGAGGCGATTGTAAGGCAGC
CCCCACCGATTGGTTAATTCGGAATAGTTGGAAA	CTGGCTGCATCGTCGCCTGGTGAAGCTAACGGAGCAAACC
CCCACCGATTGGGTTAATTCGGAAATAGTTGGAA	ACGGGGTGGTGACTAGCTCGTAGCAAGCAGTCAGCTCCCCGCCCC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CGGACTTAGGTACAGGGTTGTTTAGATGGACCTATTGGATCGCCC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CTTTTCCAAGATTTGGCAAATCAGCGGCGTGTCGTTGC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CAGATGTCACAACAAACCCTGAGGCCGCAGCATACAAGACC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CACTTGTCGGATCAGTAATTTACTGAGATCTCATCGCAGCC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CTGGGCCGGCGACTTGGTAGAGGTAACGGGGGTCCCTCTTCCTGTTTCCC
CCACCGATTGGGGTTAATTCGGAATAGTTGGAAA	CCCACTGAAAAAGTTAGAGCTGTTATTGTTATAAACGATGGCCC
CCACCGATTGGGTTTAATTCGGAATAGTTGGAAA	CTGTGGATTTAATGCTGCCGGGTCTCGTTATTGTTGTGAATACC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CCCGTAATGGCAATTTTGTTATTATCTAGGTAATGAGAAAATTCTTTCATAGC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	ACAACTCTTGGGGATCGAGGAGTACGGAAAATGCTTCATCCCC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CTCGTTGCCGATATGCAATCGCAGCGGGCAGCTCTTCTCCGTCC
CCCACCGATTGGGTTAATTCGGAATAGTTGGAAA	CGGTGTAGCCAGGATTAGAAGGGTGGTCATTGGTCAAGC
CCCCACCGATTGGGTAATTCGGAATAGTTGGAAA	CTCACGTCAACCCATAAGATCGTGTCCACAGATCCATTCGCC
CCCCACCGATTGGGTTAATTCGGAAATAGTTGGA	AACCCAGACAGTTGTGCTTTTTGACGCTAACCGTGCCAGCCCTGGC
CCCCACCGATTGGGTTAATTCGGAATAGGTTGGA	AACGACTTCCCCCAGCGGGACGCCACAGCCTCTTGAGCTGTG
CCCCCACGATTGGGTTAATTCGGAATAGTTGGAA	ACCTATGCCTTCTTCAGTTATGGCGACGCCATGTTCCTGACCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAA	ACTACTTCCTCTAGTTCAACATATCCCGATGTAACCAAC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAA	ACCCTCGCGCATCCACAGTAGGCTTTAGCAAATTTACCTCGATTGC
CCCCACCGATTGGGTTAATTCGAATAGTTGGAAA	CAACATAAAAATTTGTTTTAGTTCTTACACGCCTCAGTTTCATGCAC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAA	ACACTGAAGCCTGTCGGGTGGCCCAGCGCATCCACATGC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAA	ACCGAGAGGCAGGACCAGCGATTGCAGCAGCAGGAAGAGGAA
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAA	ACACGTATGGCCGGCCAGCAGGTTCTATGTCTATA
CCCCACCGATTGGGTTAATTCGGAATAGTTGAAC	AAGATCTCAAGTCGAGAGATCTTCAACAAATACCAAACTAG
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAA	ACCCACAGTCCCTAGGGGTTGAGGACGGAGCAGGTTTTCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAA	ACATGACTGACGCCCGGGACTCACCCGAATCCCGCAAACGAG
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAA	ACCCGAACAATAACTGTCAGGTCACCAAAGTCAATGTTGTAG
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAA	CTCAAGGCTATCGATTAAAATGCGCTCGATTTTACCCGCA
GCCCCACCGATTGGGTAATTCGGAATAGTTGGAA	ACAACTTTGAGTCCACCAGGATACCATAACAGGAGCACTA
GGCCCACCGATTGGGTTAATTCGGAAATAGTTGG	AAACCAGTTCTTTTTATAAAAAAGTTCTCACACCATAAGAGAAAGT
TCCCCACCGATTGGGTTAATTCGGAATAGTTGGA	AACGTGGTAGGAAAAGTCGCAGCAAATGGCGCGGCAC
CCCCACCGATTGGGTTTAATTCGGAATAGTTGAA	ACGTCTCCGGGTTTGTAGGGTTTTTCCTTCCTGTTATCTATATCC
CCCCCACCGATTGGGTTAATTCGGAATAGTTGGA	ACGTACAAGCAGCGGCTTCATTTGCAAGTTTACTGACTTC
ACCCCACCGATTGGGTTAATTCGGATAGTTGGAA	ACGCATCATTCCATAGTCGATCTGGTCAACTGCCCATTAGGTTAGG
CACCCACCGATTGGGTTAATTCGGAATAGTTGGA	AACATGAATTCCTGCTAAGTCAAGATTTGGTAGTTCCGACAG
GCCCCACCGATTGGGTTAATCGGAATATTTGGAA	ACCAAACGATCGAAGTTGCTGATATTTCAGCGTTGAAAGCGCT
CCCCCACCGATTGGGTTAATTCCGGAATAGTTGG	AAACGGTCGTGATTGGTCGCTACGCGGCTGAGGGTGCTCTTTACCCT
ACCCCACCGATTGGGTTAATTCGGAATAGTTGGA	AACATAGGCAAAGGAGAGATCAACCCAAAGAGGACGTCGA
CCCCACCGATTGGGGTTAATTCGGAAATAGTTGG	AAACTCAGCCCGCGACGAGCGAGCGAGGAGCACTATGCGCAGT
ACCCCACCGATTGGGTTAATTCGGAATAGTTGGA	AACCGGTTGATGCCGCCATGGAAGGCGGTACCATAGTTTCGTT
CCCCACCCGATTGGGTTTAATCGGAATAGTTGGA	AACTCACCTGAATAGTACCCAGAGATTGTGCCTGATTCAGTCC
CCCCCACCGATTGGGTTAATTCGGAATAGTTGGA	AACACCTGGCATCGACACCTGGCCTGTCACTACAACAACTGG
CCCCACCGATTGGGTTTAATTCGGAATAGTTGGA	AACTCTAAAAACTGACCCTTCCGTCATCGCCAGCGTTTCACCT
CCCCCACCGATTGGGTTAATTCGGAATAGTTGGA	AACTGAAAATCCAGAATCATGAGGACACTAAGCAACTTGT
CCCCACCCGATTGGGTTAATTCGGAATAGTTGGA	AACGACTGGCGTTTCCCAATGGGCCGAGCATTTTCATGCCGGTTC
CCCCCACCGATTGGGTTAATTCGGAATAGTTGGA	AACGGGAAGTTCCTCAAAAGTACTATATGGATTTGACTCAAG
CCCCCACCGATTGGGTTAATTCGGAATAGTTGGA	AACCAAAATCCCCGGTATTCTTCTTCTTGGATGTGAACTTC
TCCCCACCGATTGGGTTAATTCGGAATAGTTGGA	AACGCCCTCTCCCGTTGGGGTTGGCGCATGATATATCTTGGC
ACCCCACCGATTGGGTTAATTCGGAATAGTTGGA	AACATGGGGGAGCTAGGCCAGGAGCCGGTCGAAAACCTAAATA
TCCCCACCGATTGGGTTAATTCGGAATAGTTGGA	AACGTCAGTAACTGAAGCTTTGATTGAATCCCCCTTGTTA
GCCCCACCGATTGGGTTAATTCGGAATAGTTGGA	AACGATTGTTAATTGGAGTAGAGAGTCCACTTTCTGCGGTTTGCA
ACCCCACCGATTGGGTTAATTCGGAATAGTTGGA

>NZ_CP021983|6|3|826149-832001|PILER-CR
CGATTGGGTTAATTCGGAAT	AGTTGGAAACTCACAGTCCTCGCTGAATTCGCTTCATTTTGAGCCACTCACCAACCCACC
GATTGGGTTAATTCGGAATA	GTTGGAAACTCAGGGAACAAATTGATTTTGCCGTTCACCCAAATTGCGGCATAGATTACCCACCG
ATTGGGTTAATTCGGAATAG	TTGGAAACTCTTTATGCTCTGGTCTGTAGAGCTCTGGATTCAGCATCCCCCACCGA
TTGGGTTAATTCGGAATAGT	TGGAAACTGATTAAGTTCGGGAACACAACCATCTGCAGTGTTATGCCCCACCGAT
TGGGTTAATTCGGAATAGTT	GGAAACCCTCGATGTCCTTGAAGTTTTATAGGCTCTTTAGTATCCGCCCCCACCGATT
GGGTTAATTCGGAATAGTTG	GAAACCTTCTGCTAAGAAAGGATCCATCGTCAAACACGATAAACCCCCACCGATTG
GGTTAATTCGGAATAGTTGG	AAACGCTGACGTAGCGCAAACCATTCTTCAGCCAGGAAGCTTGGCCCCACCGATTGG
GTTAATTCGGAATAGTTGGA	AACCCGTAGGCCCCATTTGCAACTGCGCGAATACAGGATTCCGTGCCCCCCACCGATTGGG
TTAATTCGGAATAGTTGGAA	ACAGCAAGGGTTTCAGCCATTCCTCTCCCTTTGCTATACTCTTCCCCCCACCGATTGGGT
TAATTCGGAATAGTTGGAAA	CTCGGGTATCAGTGCTGCTCCTAGTGCCTTAACCCCAACTCAACCCCCACCGATTGGGTT
AATTCGGAATAGTTGGAAAC	TTTGGAAAGTAGTTTATATAAATTTAGATGACTCCGAAAGCCCCCACCGATTGGGTTA
ATTCGGAATAGTTGGAAACT	AAATACGGGTGGACCTTCAAAGATTTTGATTCTGTTGACCCCCCACCGATTGGGTTAA
TTCGGAATAGTTGGAAACTT	ATTCGAACCACTTGGATAAAGTCAACGAACAATTGACCCCCCACCGATTGGGGTTAATTCGGA
ATAGTTGGAAACGCGGGGAG	CAGTCAACAGGTTGGTGAGTTTCTCATGTATGTTGCCCCCACCGATTGGGTTAATTCGGAA
TAGTTGGAAACCGTAACAGA	GGTGGTCTAAGCTCTAAAACCCTTGCTGTGTAGGAGTTCCCCCACCGATTGGGTTTAATTCGGAA
TAGTTGGAAACAGTTCCTCC	AAAAGATGTTTCTCAGAGTGTGGCGACCCCCCCACCGATTGGGTTAATTCGGAAT
AGTTGGAAACAATAATCAGT	ATAAAACTGCCCATTCGTAATACAAACACCCCACCGATTGGGGTTAATTCGGAATAGTTTG
GAAACCTAGTAATCCCCTGT	TTGTTTTTGTAAGGGTAAGGCCGGTTGCCCCACCGATTGGGTTAATTCGGAATAGTTGGA
AACGAAGGACGCATTATTGA	TCTTACTGGCGCAACCAACCCCCACACCGATTGGGTTAATTCGGAATAGTTGGAA
ACCTTCGAAAGAAAAGACCT	TTTCGGTTTCTATATCTGAATCTCCCCCCACCGAATTGGGTTAATTCGGAATAGTTTGGAA
ACAAAGTATCTACAAACCCA	GCGGCGACCGCCCCCGGGCCCCCACCGATTGGGTTAATTCGGAATAGTTGGGAAA
CAAAGCTTGGGCCAGCTCTA	AAGCACTGGCATCAACTTCCCCCCACCCGATTGGGTTAATTCGGAATAGTTGGAAACT
GTTCAGGGTGTTCAATGGTA	GTTGTTTTAGTTAGCCCCCACCGATTGGGGTTAATTCGGAATAGTTGGAAACGTTAAGT
AAAAATTTTATTGAAAGAGT	TCTTACCTTAACCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCAAATACA
TCCAGTCATAGAGGCGATTG	TAAGGCAGCCCCCACCGATTGGTTAATTCGGAATAGTTGGAAACTGGCTGCATCGTCGC
CTGGTGAAGCTAACGGAGCA	AACCCCCACCGATTGGGTTAATTCGGAAATAGTTGGAAACGGGGTGGTGACTAGC
TCGTAGCAAGCAGTCAGCTC	CCCGCCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGGACTTAGGTACAGGGT
TGTTTAGATGGACCTATTGG	ATCGCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTTTTCCAAGATTTGGCAA
ATCAGCGGCGTGTCGTTGCC	CCACCGATTGGGTTAATTCGGAATAGTTGGAAACAGATGTCACAACAAACCCT
GAGGCCGCAGCATACAAGAC	CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACACTTGTCGGATCAGTAATTT
ACTGAGATCTCATCGCAGCC	CCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTGGGCCGGCGACTTGGTAGAG
GTAACGGGGGTCCCTCTTCC	TGTTTCCCCCACCGATTGGGGTTAATTCGGAATAGTTGGAAACCCACTGAAAAAGTTAGAGCTGTTATTG
TTATAAACGATGGCCCCCAC	CGATTGGGTTTAATTCGGAATAGTTGGAAACTGTGGATTTAATGCTGCCGGGTCTCGT
TATTGTTGTGAATACCCCCA	CCGATTGGGTTAATTCGGAATAGTTGGAAACCCGTAATGGCAATTTTGTTATTATCTAG
GTAATGAGAAAATTCTTTCA	TAGCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAACAACTCTTGGGGATCGAGGAGTACGGAAA
ATGCTTCATCCCCCCCACCG	ATTGGGTTAATTCGGAATAGTTGGAAACTCGTTGCCGATATGCAATCGCAGCGGGCAG
CTCTTCTCCGTCCCCCACCG	ATTGGGTTAATTCGGAATAGTTGGAAACGGTGTAGCCAGGATTAGAAGGGTGGTCATTG
GTCAAGCCCCCACCGATTGG	GTAATTCGGAATAGTTGGAAACTCACGTCAACCCATAAGATCGTGTCCACAGATC
CATTCGCCCCCCACCGATTG	GGTTAATTCGGAAATAGTTGGAAACCCAGACAGTTGTGCTTTTTGACGCTAACCGTGC
CAGCCCTGGCCCCCACCGAT	TGGGTTAATTCGGAATAGGTTGGAAACGACTTCCCCCAGCGGGACGCCACAGCCTCTTGAG
CTGTGCCCCCACGATTGGGT	TAATTCGGAATAGTTGGAAACCTATGCCTTCTTCAGTTATGGCGACGCCATGTTCCT
GACCCCCCCACCGATTGGGT	TAATTCGGAATAGTTGGAAACTACTTCCTCTAGTTCAACATATCCCGATGTAACCAAC
CCCCACCGATTGGGTTAATT	CGGAATAGTTGGAAACCCTCGCGCATCCACAGTAGGCTTTAGCAAATTTACCTC
GATTGCCCCCACCGATTGGG	TTAATTCGAATAGTTGGAAACAACATAAAAATTTGTTTTAGTTCTTACACGCCTCAGTTTC
ATGCACCCCCACCGATTGGG	TTAATTCGGAATAGTTGGAAACACTGAAGCCTGTCGGGTGGCCCAGCGCATCCACATGCCCCCAC
CGATTGGGTTAATTCGGAAT	AGTTGGAAACCGAGAGGCAGGACCAGCGATTGCAGCAGCAGGAAGAGGAACCCC
ACCGATTGGGTTAATTCGGA	ATAGTTGGAAACACGTATGGCCGGCCAGCAGGTTCTATGTCTATACCCCACCGATTG
GGTTAATTCGGAATAGTTGA	ACAAGATCTCAAGTCGAGAGATCTTCAACAAATACCAAACTAGCCCCACC
GATTGGGTTAATTCGGAATA	GTTGGAAACCCACAGTCCCTAGGGGTTGAGGACGGAGCAGGTTTTCCCCCCACCGA
TTGGGTTAATTCGGAATAGT	TGGAAACATGACTGACGCCCGGGACTCACCCGAATCCCGCAAACGAGCCCCACCG
ATTGGGTTAATTCGGAATAG	TTGGAAACCCGAACAATAACTGTCAGGTCACCAAAGTCAATGTTGTAGCCCCACCGA
TTGGGTTAATTCGGAATAGT	TGGAACTCAAGGCTATCGATTAAAATGCGCTCGATTTTACCCGCAGCCCCACCGATT
GGGTAATTCGGAATAGTTGG	AAACAACTTTGAGTCCACCAGGATACCATAACAGGAGCACTAGGCCCACCGATTGG
GTTAATTCGGAAATAGTTGG	AAACCAGTTCTTTTTATAAAAAAGTTCTCACACCATAAGAGAAAGTTCCCCACCGA
TTGGGTTAATTCGGAATAGT	TGGAAACGTGGTAGGAAAAGTCGCAGCAAATGGCGCGGCACCCCCACCGATTGGGTTTAAT
TCGGAATAGTTGAAACGTCT	CCGGGTTTGTAGGGTTTTTCCTTCCTGTTATCTATATCCCCCCCACCGATT
GGGTTAATTCGGAATAGTTG	GAACGTACAAGCAGCGGCTTCATTTGCAAGTTTACTGACTTCACCCCACCGATTGGGTTA
ATTCGGATAGTTGGAAACGC	ATCATTCCATAGTCGATCTGGTCAACTGCCCATTAGGTTAGGCACCCACCGATTG
GGTTAATTCGGAATAGTTGG	AAACATGAATTCCTGCTAAGTCAAGATTTGGTAGTTCCGACAGGCCCCACCGATTGGGTTA
ATCGGAATATTTGGAAACCA	AACGATCGAAGTTGCTGATATTTCAGCGTTGAAAGCGCTCCCCCACCGATTGGGTTA
ATTCCGGAATAGTTGGAAAC	GGTCGTGATTGGTCGCTACGCGGCTGAGGGTGCTCTTTACCCTACCCCACCGATTGGGTTAATT
CGGAATAGTTGGAAACATAG	GCAAAGGAGAGATCAACCCAAAGAGGACGTCGACCCCACCGATTGGGGTTAATTCGGAAATAGTTG
GAAACTCAGCCCGCGACGAG	CGAGCGAGGAGCACTATGCGCAGTACCCCACCGATTGGGTTAATTCGGAATAGTTGGAAA
CCGGTTGATGCCGCCATGGA	AGGCGGTACCATAGTTTCGTTCCCCACCCGATTGGGTTTAATCGGAATAGTTGGAAAC
TCACCTGAATAGTACCCAGA	GATTGTGCCTGATTCAGTCCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACA
CCTGGCATCGACACCTGGCC	TGTCACTACAACAACTGGCCCCACCGATTGGGTTTAATTCGGAATAGTTGGAAACTCT
AAAAACTGACCCTTCCGTCA	TCGCCAGCGTTTCACCTCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTG
AAAATCCAGAATCATGAGGA	CACTAAGCAACTTGTCCCCACCCGATTGGGTTAATTCGGAATAGTTGGAAACGACTGG
CGTTTCCCAATGGGCCGAGC	ATTTTCATGCCGGTTCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGG
GAAGTTCCTCAAAAGTACTA	TATGGATTTGACTCAAGCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCAAAAT
CCCCGGTATTCTTCTTCTTG	GATGTGAACTTCTCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGCCCTCTC
CCGTTGGGGTTGGCGCATGA	TATATCTTGGCACCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACATGGGGGA
GCTAGGCCAGGAGCCGGTCG	AAAACCTAAATATCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGTCAGTAA
CTGAAGCTTTGATTGAATCC	CCCTTGTTAGCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGATTGTTAATTG
GAGTAGAGAGTCCACTTTCT	GCGGTTTGCAACCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCGAAGAAA
AGAACGAGGGCGGAGGGCGG	AAGAACGAGGAGATTAGAGTGAAGGTGCTCACAAATGATGAGCCTCTCACCATTGGACTC


>NZ_CP021983|6|7|831060-832012|CRISPRCasFinder
	CGCTTGAACACCCGGATCAGTATCCGCAGCGATC
GCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TCACAGTCCTCGCTGAATTCGCTTCATTTTGAGCCACTCACCA
ACCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TCAGGGAACAAATTGATTTTGCCGTTCACCCAAATTGCGGCATAGATT
ACCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TCTTTATGCTCTGGTCTGTAGAGCTCTGGATTCAGCATC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TGATTAAGTTCGGGAACACAACCATCTGCAGTGTTATG
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CCTCGATGTCCTTGAAGTTTTATAGGCTCTTTAGTATCCGC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CTTCTGCTAAGAAAGGATCCATCGTCAAACACGATAAAC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	GCTGACGTAGCGCAAACCATTCTTCAGCCAGGAAGCTTGG
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CCGTAGGCCCCATTTGCAACTGCGCGAATACAGGATTCCGTGCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	AGCAAGGGTTTCAGCCATTCCTCTCCCTTTGCTATACTCTTCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TCGGGTATCAGTGCTGCTCCTAGTGCCTTAACCCCAACTCAAC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TTTGGAAAGTAGTTTATATAAATTTAGATGACTCCGAAAGC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TAAATACGGGTGGACCTTCAAAGATTTTGATTCTGTTGACC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TTATTCGAACCACTTGGATAAAGTCAACGAACAATTGACCC
CCCACCGATTGGGGTTAATTCGGAATAGTTGGAAAC	GCGGGGAGCAGTCAACAGGTTGGTGAGTTTCTCATGTATGTTGC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CGTAACAGAGGTGGTCTAAGCTCTAAAACCCTTGCTGTGTAGGAGTTCC
CCCACCGATTGGGTTTAATTCGGAATAGTTGGAAAC	AGTTCCTCCAAAAGATGTTTCTCAGAGTGTGGCGACCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	AATAATCAGTATAAAACTGCCCATTCGTAATACAAACAC
CCCACCGATTGGGGTTAATTCGGAATAGTTTGGAAA	CCTAGTAATCCCCTGTTTGTTTTTGTAAGGGTAAGGCCGGTTG
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	GAAGGACGCATTATTGATCTTACTGGCGCAACCAACCC
CCACACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CTTCGAAAGAAAAGACCTTTTCGGTTTCTATATCTGAATCTCCC
CCCACCGAATTGGGTTAATTCGGAATAGTTTGGAAA	CAAAGTATCTACAAACCCAGCGGCGACCGCCCCCGGGC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGGAAA	CAAAGCTTGGGCCAGCTCTAAAGCACTGGCATCAACTTCCC
CCCACCCGATTGGGTTAATTCGGAATAGTTGGAAAC	TGTTCAGGGTGTTCAATGGTAGTTGTTTTAGTTAGCC
CCCACCGATTGGGGTTAATTCGGAATAGTTGGAAAC	GTTAAGTAAAAATTTTATTGAAAGAGTTCTTACCTTAAC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CAAATACATCCAGTCATAGAGGCGATTGTAAGGCAG
CCCCCACCGATTGGTTAATTCGGAATAGTTGGAAAC	TGGCTGCATCGTCGCCTGGTGAAGCTAACGGAGCAAAC
CCCCACCGATTGGGTTAATTCGGAAATAGTTGGAAA	CGGGGTGGTGACTAGCTCGTAGCAAGCAGTCAGCTCCCCGCCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	GGACTTAGGTACAGGGTTGTTTAGATGGACCTATTGGATCGCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TTTTCCAAGATTTGGCAAATCAGCGGCGTGTCGTTG
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	AGATGTCACAACAAACCCTGAGGCCGCAGCATACAAGAC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	ACTTGTCGGATCAGTAATTTACTGAGATCTCATCGCAGC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TGGGCCGGCGACTTGGTAGAGGTAACGGGGGTCCCTCTTCCTGTTTCC
CCCACCGATTGGGGTTAATTCGGAATAGTTGGAAAC	CCACTGAAAAAGTTAGAGCTGTTATTGTTATAAACGATGGCC
CCCACCGATTGGGTTTAATTCGGAATAGTTGGAAAC	TGTGGATTTAATGCTGCCGGGTCTCGTTATTGTTGTGAATAC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CCGTAATGGCAATTTTGTTATTATCTAGGTAATGAGAAAATTCTTTCATAG
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAA	CAACTCTTGGGGATCGAGGAGTACGGAAAATGCTTCATCCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TCGTTGCCGATATGCAATCGCAGCGGGCAGCTCTTCTCCGTC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	GGTGTAGCCAGGATTAGAAGGGTGGTCATTGGTCAAG
CCCCCACCGATTGGGTAATTCGGAATAGTTGGAAAC	TCACGTCAACCCATAAGATCGTGTCCACAGATCCATTCGCC
CCCCACCGATTGGGTTAATTCGGAAATAGTTGGAAA	CCCAGACAGTTGTGCTTTTTGACGCTAACCGTGCCAGCCCTGGC
CCCCACCGATTGGGTTAATTCGGAATAGGTTGGAAA	CGACTTCCCCCAGCGGGACGCCACAGCCTCTTGAGCTGTG
CCCCCACGATTGGGTTAATTCGGAATAGTTGGAAAC	CTATGCCTTCTTCAGTTATGGCGACGCCATGTTCCTGACCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TACTTCCTCTAGTTCAACATATCCCGATGTAACCAAC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CCTCGCGCATCCACAGTAGGCTTTAGCAAATTTACCTCGATTG
CCCCCACCGATTGGGTTAATTCGAATAGTTGGAAAC	AACATAAAAATTTGTTTTAGTTCTTACACGCCTCAGTTTCATGCAC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	ACTGAAGCCTGTCGGGTGGCCCAGCGCATCCACATGC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CGAGAGGCAGGACCAGCGATTGCAGCAGCAGGAAGAGGAA
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	ACGTATGGCCGGCCAGCAGGTTCTATGTCTATA
CCCCACCGATTGGGTTAATTCGGAATAGTTGAACAA	GATCTCAAGTCGAGAGATCTTCAACAAATACCAAACTAG
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CCACAGTCCCTAGGGGTTGAGGACGGAGCAGGTTTTCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	ATGACTGACGCCCGGGACTCACCCGAATCCCGCAAACGAG
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CCGAACAATAACTGTCAGGTCACCAAAGTCAATGTTGTAG
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAACT	CAAGGCTATCGATTAAAATGCGCTCGATTTTACCCGCA
GCCCCACCGATTGGGTAATTCGGAATAGTTGGAAAC	AACTTTGAGTCCACCAGGATACCATAACAGGAGCACTAG
GCCCACCGATTGGGTTAATTCGGAAATAGTTGGAAA	CCAGTTCTTTTTATAAAAAAGTTCTCACACCATAAGAGAAAGTT
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	GTGGTAGGAAAAGTCGCAGCAAATGGCGCGGCAC
CCCCACCGATTGGGTTTAATTCGGAATAGTTGAAAC	GTCTCCGGGTTTGTAGGGTTTTTCCTTCCTGTTATCTATATCCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAACG	TACAAGCAGCGGCTTCATTTGCAAGTTTACTGACTTCA
CCCCACCGATTGGGTTAATTCGGATAGTTGGAAACG	CATCATTCCATAGTCGATCTGGTCAACTGCCCATTAGGTTAGGC
ACCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	ATGAATTCCTGCTAAGTCAAGATTTGGTAGTTCCGACAG
GCCCCACCGATTGGGTTAATCGGAATATTTGGAAAC	CAAACGATCGAAGTTGCTGATATTTCAGCGTTGAAAGCGCTC
CCCCACCGATTGGGTTAATTCCGGAATAGTTGGAAA	CGGTCGTGATTGGTCGCTACGCGGCTGAGGGTGCTCTTTACCCTA
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACATAGGCAAAGGAGAGATCAACCCAAAGAGGACGTCGACCCCACCGATTGGGGTTAATTCGGAAATAGTTGGAAACTCAGCCCGCGACGAGCGAGCGAGGAGCACTATGCGCAGTACCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CGGTTGATGCCGCCATGGAAGGCGGTACCATAGTTTCGTTC
CCCACCCGATTGGGTTTAATCGGAATAGTTGGAAAC	TCACCTGAATAGTACCCAGAGATTGTGCCTGATTCAGTCCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	ACCTGGCATCGACACCTGGCCTGTCACTACAACAACTGGC
CCCACCGATTGGGTTTAATTCGGAATAGTTGGAAAC	TCTAAAAACTGACCCTTCCGTCATCGCCAGCGTTTCACCTC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	TGAAAATCCAGAATCATGAGGACACTAAGCAACTTGTC
CCCACCCGATTGGGTTAATTCGGAATAGTTGGAAAC	GACTGGCGTTTCCCAATGGGCCGAGCATTTTCATGCCGGTTCC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	GGGAAGTTCCTCAAAAGTACTATATGGATTTGACTCAAGC
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	CAAAATCCCCGGTATTCTTCTTCTTGGATGTGAACTTCT
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	GCCCTCTCCCGTTGGGGTTGGCGCATGATATATCTTGGCA
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	ATGGGGGAGCTAGGCCAGGAGCCGGTCGAAAACCTAAATAT
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	GTCAGTAACTGAAGCTTTGATTGAATCCCCCTTGTTAG
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC	GATTGTTAATTGGAGTAGAGAGTCCACTTTCTGCGGTTTGCAA
CCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_080809559.1|840735_841116_-|cation:proton-antiporter	unknown	unknown	unknown
NZ_CP021983.1|WP_080808773.1|814400_816113_-|RAMP-superfamily-protein	unknown	unknown	gnl|CDD|213662
NZ_CP021983.1|WP_080808744.1|825595_825871_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|187856
NZ_CP021983.1|WP_088429135.1|835427_836579_-|ISAs1-family-transposase	unknown	unknown	gnl|CDD|379382
NZ_CP021983.1|WP_080809565.1|840183_840462_-|sodium:proton-antiporter	unknown	unknown	gnl|CDD|377023
NZ_CP021983.1|WP_088431512.1|833018_833363_+|DUF559-domain-containing-protein	unknown	unknown	gnl|CDD|225408
NZ_CP021983.1|WP_080808767.1|816785_817835_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	gnl|CDD|224255
NZ_CP021983.1|WP_080809504.1|837129_838302_-|transposase	unknown	unknown	gnl|CDD|376573
NZ_CP021983.1|WP_080813283.1|838896_839559_-|cation:proton-antiporter	unknown	unknown	gnl|CDD|237140
NZ_CP021983.1|WP_088429131.1|822428_823046_+|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NZ_CP021983.1|WP_080808770.1|816344_816767_-|hypothetical-protein	cmr5gr11	mkCas0065_cmr5gr11_CAS-III-B	unknown
NZ_CP021983.1|WP_080808756.1|823943_824363_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080808763.1|819175_821074_-|hypothetical-protein	cas10	cd09679_cas10_CAS-III	gnl|CDD|187810
NZ_CP021983.1|WP_088429133.1|824591_825596_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|376633
NZ_CP021983.1|WP_080813281.1|839555_840191_-|DUF4040-domain-containing-protein	unknown	unknown	gnl|CDD|236006
NZ_CP021983.1|WP_080809556.1|841112_842546_-|cation:proton-antiporter	unknown	unknown	gnl|CDD|235978
NZ_CP021983.1|WP_080808766.1|817964_819155_-|hypothetical-protein	cmr3gr5	pfam09700_cmr3gr5_CAS-III-B	gnl|CDD|187879
NZ_CP021983.1|WP_080808759.1|821386_822100_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080806623.1|834015_835062_-|IS5/IS1182-family-transposase	unknown	unknown	gnl|CDD|377531
NZ_CP021983.1|WP_080809562.1|840458_840710_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP021983.1|WP_088429133.1|824591_825596_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	9.4e-95	312.0	0.0
NZ_CP021983.1|WP_080808744.1|825595_825871_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	5.3e-28	92.0	0.0
NZ_CP021983.1|WP_080808766.1|817964_819155_-|hypothetical-protein	cmr3gr5	pfam09700_cmr3gr5_CAS-III-B	3e-18	61.3	0.0
NZ_CP021983.1|WP_080808767.1|816785_817835_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	8.5e-21	69.3	0.0
NZ_CP021983.1|WP_080808770.1|816344_816767_-|hypothetical-protein	cmr5gr11	mkCas0065_cmr5gr11_CAS-III-B	2.2e-54	177.3	1.7
NZ_CP021983.1|WP_080808763.1|819175_821074_-|hypothetical-protein	cas10	cd09679_cas10_CAS-III	5.2e-22	73.0	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_080808773.1|814400_816113_-|RAMP-superfamily-protein	gnl|CDD|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	0.000225146
NZ_CP021983.1|WP_080808744.1|825595_825871_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.55066e-29
NZ_CP021983.1|WP_088429135.1|835427_836579_-|ISAs1-family-transposase	gnl|CDD|379382	pfam13808, DDE_Tnp_1_assoc, DDE_Tnp_1-associated. This domain is frequently found N-terminal to the transposase, IS family DDE_Tnp_1, pfam01609 and its relatives.	7.44417e-19
NZ_CP021983.1|WP_080809565.1|840183_840462_-|sodium:proton-antiporter	gnl|CDD|377023	pfam03334, PhaG_MnhG_YufB, Na+/H+ antiporter subunit. This family includes PhaG from Rhizobium meliloti, MnhG from Staphylococcus aureus, YufB from Bacillus subtilis.	7.23743e-11
NZ_CP021983.1|WP_088431512.1|833018_833363_+|DUF559-domain-containing-protein	gnl|CDD|225408	COG2852, COG2852, Very-short-patch-repair endonuclease [Replication, recombination, and repair].	9.00616e-34
NZ_CP021983.1|WP_080808767.1|816785_817835_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl|CDD|224255	COG1336, COG1336, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	9.97971e-16
NZ_CP021983.1|WP_080809504.1|837129_838302_-|transposase	gnl|CDD|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	0.000108412
NZ_CP021983.1|WP_080813283.1|838896_839559_-|cation:proton-antiporter	gnl|CDD|237140	PRK12567, PRK12567, putative monovalent cation/H+ antiporter subunit B; Reviewed.	2.47262e-102
NZ_CP021983.1|WP_088429131.1|822428_823046_+|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	3.51274e-27
NZ_CP021983.1|WP_080808763.1|819175_821074_-|hypothetical-protein	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	2.9475e-16
NZ_CP021983.1|WP_088429133.1|824591_825596_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	2.7399e-109
NZ_CP021983.1|WP_080813281.1|839555_840191_-|DUF4040-domain-containing-protein	gnl|CDD|236006	PRK07377, PRK07377, hypothetical protein; Provisional.	1.70249e-77
NZ_CP021983.1|WP_080809556.1|841112_842546_-|cation:proton-antiporter	gnl|CDD|235978	PRK07234, PRK07234, putative monovalent cation/H+ antiporter subunit D; Reviewed.	0
NZ_CP021983.1|WP_080808766.1|817964_819155_-|hypothetical-protein	gnl|CDD|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	2.47807e-06
NZ_CP021983.1|WP_080806623.1|834015_835062_-|IS5/IS1182-family-transposase	gnl|CDD|377531	pfam05598, DUF772, Transposase domain (DUF772). This presumed domain is found at the N-terminus of many proteins found in transposons.	6.57123e-24

Protein sequences

>NZ_CP021983.1|WP_080808744.1|825595_825871_+|CRISPR-associated-endonuclease-Cas2
MLVLITYDIPDNKRRTKLATFLEGYGRRVQKSVFECFLTQAEMQELHRRIQRRVNPDEDNVRFYWLTPQSVAKSLAIGSDPPTPPPNVYII
>NZ_CP021983.1|WP_088429133.1|824591_825596_+|CRISPR-associated-endonuclease-Cas1
MCDLYVVKQGTCLRKEHGRFILNPPEDDGLEIPIREIERILLFGNIQLSTAVIGTCLQQQIPVVFLSRTGIYKGHLWSAELRDLEAERNQFLNYTDRTFHLETARAIIRGKLVNSRQLLLRLNRKRHLETVANAISGIQRDINASETAGSVDQLRGYEGITAARYFPALGQLLITPDFTFEERNRRPPRDPVNSLLSFGYTLLSNNVMSLILAEGLNPYLGNLHRSDKKLPELVLDLMEEFRSPVVDTLVVTLINRRTLHPDDFTWPTETGGVYIADAARRRFIHAFEANMNQSVKHPDVQEPVTYRRAIHYQVKRYKRALLEVIPYQPFVRAA
>NZ_CP021983.1|WP_080808756.1|823943_824363_+|hypothetical-protein
MARRKRNSATLEQVERRLESIRSIATDLDLGGGLSVQNFAIIVGDLAAKLAAYNTALSNIDKMADDVRVAEQAAKTMAENMLLGIGSHYGKTSQEYGMAGGSRRRGYRHPQVADPVPDPVTIPVVEPSQNGASAEPVLV
>NZ_CP021983.1|WP_088429131.1|822428_823046_+|Uma2-family-endonuclease
MVTIPLPDAQLMSFDEFIAWKPDNQPYELHHGTPIEMQPTGDHEEIIAFLNSVLVLEVHRLQQPLMLPKQALVKLPDEDTAYLPDVLLLNREALPQEPLWKRASTVTQGISVPLVIEVVSTNWRDDYGKKLVDYESLGIAEYWIVDHLGLGGRRYIGYPKQPTLSVYRLVDDEYQVRQFRGQEPIQSGLFPDLALTATAIFRAGP
>NZ_CP021983.1|WP_080808759.1|821386_822100_-|hypothetical-protein
MVLLHAVIAQATSDPATPTDLIKLFRESHAQLTTSFNLFVGAISTIFVVVGILLAFVGVRTRQEVQQTIQEVKLSVAEQVRSEVDRQIATKVDEEIGYIKKMVGREAAIGRTQVDYVFVAGEPERYPTEYDLLDARGFQMAPFLYDPERAWPESHVFVLDLMTPSLSPERKEALVKEAAAKLTQRRRPTVLVIYVKGIIEAVNTFPEDFNYIMSNMRGTLISAVVDAAQITQALRSQ
>NZ_CP021983.1|WP_080808763.1|819175_821074_-|hypothetical-protein
MSKPVYTAITFAPIQGFIENSRKLRDLYGSSYLLSFLSWAICSAQPECSVISPALPNVRQGMPNLILVRGNVPPEETETAFFSAWQCVVDTCRQWIECKISDAYYWERSWGLWAKYAWEFFIATGCSIPAARTAVLEKKRSRNWTGVNWTGESSTLSGADGIAWPKLGYLSPRDINYQQQKTEIEAFYATLSRTLGQAFIEAVGLTPADPETKAIEYGAAFVDPDEELSIPELVKRLVTHKALSERIQTNYQSQVRDYDLDRDQLQSITAIAHELDPQRFTDLNRLKRKYKKANQALEPEYWTGWFMGDGDNAGNYLAHHCHSDEDYTDFSCQMRQWGQRLYQNEWPQADGNGQTEPILPGNGRMIYAGGDDFLGVLYRERAEIQPHECLHWFSTFKSHVWENPDLTRPSAAVSNAPPTSDNDSKPITVSVGFVWAAPKVPQRDVLQHCREAEKSAKRHGKDRIAFRILFNGGNHLEWVCPWWLLEGDFSGSQDLDSLDTHDLSGLMPTCNDPGWTHIYNDIAVLEARHAFHGAQIDVALGLIEVYFGRPYRQLLGHPSNWWNRDDPNTGKRLFSGILGDPQRYMPEFDSSNDAWQRLNTHRFVLRDFNTWVINLAKVGFHLNRSDMAQLAA
>NZ_CP021983.1|WP_080808766.1|817964_819155_-|hypothetical-protein
MTTDSPSLPPFQYLITIQPLGLLYGSTGRFLSPENLVGRSGSQFPPSTAVLSGLIAAHYAQHAESKQALDDILKPLCLAGPFWQWTHTADRENIYVPTPMNCLAKLEPQHDATDVSEGSLVNRLEWDGQSWQPISDKALGKPEGGTWVAINDWKKLNEWQPDYQEPTVYGDPWRYTPHLHPYLMENERRVDADRERGSLFLENGVQMHPETCLVYLSNLSVENGWYRFGGEGHMVELTCHPISAGSELHKLLSHPLGKSFALITPAVWGSNRLSYRSPRLLKKGDKSRHQLAEINRDLAKLWDVATLITERPTTFRYRLGNRKNQQGEDVHQPNQPKVLSRGRYAVPAGSVYVLQDTFPDHHATWQDWPLDWFPREGPSLKRWGCGLALPVSGALP
>NZ_CP021983.1|WP_080808767.1|816785_817835_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MYHRAYGIIETLAPLHVGASAGEETGNLNLIFRDQFTQTGIIPGSSIRGRFRADMRLRRQQHLEASLKAAGVDLPAATARKVSSPEDPKKRLPRLEWLEQEAEKQSISVPELVNENHWYGHHAVTGQEDGGTTEALVKFEYASLVWIPVFCPGQPVVWVSCPRLLRRYKQITGKPEPVLRPKAAADGQPKQYPVKLREHRDRLFFNLGFLDNLAETPDLSNWVPKDSQIQPDNLVVVDDQDISIIHDMALYRQTRTKLEDDVKKVENFFGFEALPEDSILIFPIAVKDSVPHYDRASDASADGSARWKPFKNRTLRELYFGGLESIGCGHCEVTLAGDYFGDTPDDADA
>NZ_CP021983.1|WP_080808770.1|816344_816767_-|hypothetical-protein
MGWQAYGLDREAQWLVLQALDIDNDKDIKGDACLRESYKMRESVAYGLERFWGEHMRHQGKQEKKSRYWKATWDILANILGPADVTLPNDSDPKAMAQKLWGEIPVDSSGKMLTLEDQRLALAVLTQLCDCLVWWTQRYK
>NZ_CP021983.1|WP_080808773.1|814400_816113_-|RAMP-superfamily-protein
MSTLTDAANKVPLMFRAQVEGRCQVQRLIPKALEQDAERWADEWVDKAYPDAPNFGKDVQTRPYALSWRFITNSGQDDGVIRPVIGARGWPFYPGSSMKGVFRQAAHQLERAGELKLGTCDRYCGEKLENNDFRPGILRFHGGYPTDTRWTQNLVDIVHPQQQWQVKSNDKEGGAFIQISLYKPELIVGISSTTPLDDLEWEQIWHIWETALSLGLGCRVSAGYGQPQQRSGDILYRTRLKGQGQAAKLVDGTGEFRPNVFRAAIRGHALRIFGGLTNADQAEGLVQDLFGGIRGGATVGLLSMAFLDTQLELDDFGQGSYSQPTYTVEGELLWRLTRDLPQPQRQALTKLIEALTRFAMVFGGFGKSWRRADHRLVYPDYYDQGYKPLIGCHWEWLGKRSQVRDVRVRKLEKVGDFIAEVRQAAKEWMQLQTRTPQLDTHANWREAWHPDKVQVWGRETDGLEDCEAVRWLHGPYREAIPSVGIPEGSIYRSSITGQMGNVGRLWHRMYPKVRLVKDPENPKKPMPLVTRQYFELVTVFPDDSVESEQLLGFLNGQQTLFKKLWPMPRH
>NZ_CP021983.1|WP_088431512.1|833018_833363_+|DUF559-domain-containing-protein
MVEVARDLRQQQTPSEEKLWQQLRRKQRGYRVRRQQPIGPFIVDFYISQARLVIEVDGAVHTQHIEKDKQRQDLLEELGLTVLRFSTTAVEQTLSEVLEQIDTYVQILTTQTNI
>NZ_CP021983.1|WP_080806623.1|834015_835062_-|IS5/IS1182-family-transposase
MGQQGFWDIEERQQKLEQKKAVLNRLNQLVPWETFRPILMQIREKPRKSQAGRNPTDVLLLFKMLVLQKLYNISDDELEYQVNDRLSFMQFLGLGLEDRVPDATTVWLFREQLQQHGLVEALFEQFGAYLQGAGYAAKDGQIVDATLIPVPKQRNTREENQTLKQGEVPVEWQETPHQLAQKDVDARWTKKNGTSHYGYKNHINSDAGFKLIRRYSVTDASVHDSQVLGELLDADNSGDGLWADSAYLSVLIVEVLKLIGFEPHINERAYRNRPLSEAQKTANRERSKTRARVEHIFGDVVTSMGGKVVRSIGLARAQTQLGLKNLVYNLKRFVCLETQRAASAELAR
>NZ_CP021983.1|WP_088429135.1|835427_836579_-|ISAs1-family-transposase
MRLPPTPTTLDSRHEPAVERIEILEAFVALPDVRQASGKRHQMALCLALFTLAVTAGNRGFLAIGDWLKSYRSELIDLFNPPKGRLPSYSTIRRVLLKLDYGQYSAALARFFGIEPLAGETLAVDGKVLRGSYQLETDNPDSPPHPAILLVSAYLVERGLILEPYQVEHKTNEIKALPEFIKQLALKGVVIAFDAISTQKNCQLILDTDNHYLGALKGNQGNLHKSVQANFIAEDSYTEVSKGHGRLEKRVVSLCTTLDNIKPWPGLKTLIRVESERHFKKGGQPHLETETRYYVASFLESAESLARRIRGYWGVENKVHHIRDVTQGEDASRIRMHQLPQIFAVARNFALNLYRSNEFANMAQAERLCKFGLDTLKAIFRMK
>NZ_CP021983.1|WP_080809504.1|837129_838302_-|transposase
MPSSTQLYDQLLHYLRQYSHYRDLRHIKALSWMVTALICSGELSPPAWESYVISRANKAQSFERRWHRFFGNRLVEINQLYLPLVLLTLRQWEGKRLYLALDTTVLWNQYCMIHLSVVCCGRAVPLLWRVLEHGSATVAFEEYRPLLRRARWLLRQYPNLMLLADRGFANHDLMSWLQASSWHYCLRVPCDVLLHGPRRYPTEVRYLWPPKGEAIFYRNVRLWQDGSHQCNIVLATLKGVKEPWAVITDEPPTLQTLWRYALRFRVEELFLDSKSGAFEIEDSRIRSAVALERLYLVAAIALLYGTTTGMAVQIEGLRQQVDPHWRRGLSYLKIGLRWLKGVVHKGRQLLEPIALLVRDPEPCFASKKAEHDYYDQIWFSRIRSLSCRLE
>NZ_CP021983.1|WP_080813283.1|838896_839559_-|cation:proton-antiporter
MIWVYMAAGIALYIKMLAFPSPAMDATELSIVESIVQESGVPNTVSGIIFRNRLYDTIFEVVVFTLAIMGVRFLLADETPSCAIYQFTDTPSIVLARLGATIAALIGIELAIRGHLSPGGGFAAGVAGGTAIGLIAITSSTKWMEAIYQRWRAATWEKVSVLIFIVVAALTLVGIELPQGDLGALVSGGWIPVLNILVAIKVALGAWAAVLMFIRYRGLL
>NZ_CP021983.1|WP_080813281.1|839555_840191_-|DUF4040-domain-containing-protein
MAEDMYMVAIVLLLPLTAGMLVTQTNPYHGLVIRGILGAVAALVYALFGAADVALTEALVGTMLSITLYAVAVRSSLSMRLGVLAPDASSHSGPTVESEAWEPLLATLRTCLGRHHMRLELVPYPNLQALQSALKTKEVHTICRVPVLESPWDSTAAPYDLETRVHRLYELLQAELSPSLARLSHVAPASVGHSHSRTTGVGEVNSPEVQP
>NZ_CP021983.1|WP_080809565.1|840183_840462_-|sodium:proton-antiporter
MINACSYALIGIGIAFWFWGTVPLLGNRSVLFKLHTLSVSDTLGSMAIMVGLLLKIPREWPLLLLALISLAIWNTVLGYVLAYCSSAGGDHG
>NZ_CP021983.1|WP_080809562.1|840458_840710_-|hypothetical-protein
MNWLLSVMVIALMIPIYEAWQDNNAWQKILAFASIATKTSIMILVVSVLRDDWMIGVVGVLILSVGNAALMLLAHIIRRMNEV
>NZ_CP021983.1|WP_080809559.1|840735_841116_-|cation:proton-antiporter
MIRCLDLILRLTIWLLLTSDISLANIGIGTGVALLLPRHPVPTPVLRDWLHIIGRILVAIPKAYIEAIEMVIFPHTREEFTQERVRPNRSPGLVFLDILLITFTPKTIAVNYHQEGWYEVHRLRRR
>NZ_CP021983.1|WP_080809556.1|841112_842546_-|cation:proton-antiporter
MSTFTVAWICLPLFLGFGGYLLPKLIRHLALAVTLVSLGYGLRHLLAPASLTLELLDQAGVTLTVDSLSGFFIVTNALVTIAVVLYCWSSDKSAFFYTQIIILHGSVNAAFICADFISLYVALEVISIAAFLLIAYPRSDRSIWVGLRYLFVSNTAMLFYLIGAVLVYQGNQSFGFAGLQSAPTEATALIMLGLLTKGGIFISGLWLPLTHSESATPVSALLSGVVIKAGVFPLVRCALMVDSIAPIVRLFGVATALLGIGYAIFESDTKRMLALSTISQMGFVLAAPAAAGFYALTHGLVKAALFLTVGNLPNRNLKQLQQQRIPTSIWIALVIASLSISGFPLLSGFGAKVLTMKSLVSWQVIAMNLAALGTAILFAKFIFLPHGDETKAPVKSGFWMAIIVLLGGLIIANSVHSEVYTLTNLVKPLLTILIGWLAYGAVLQRTTLKLPRVLEEFEHLIGAMSLVIIALFWMVLA

Crispr_ID: NZ_CP021983_7

• CRISPR_ID: NZ_CP021983_7
• CRISPR_location: 1091429-1091515
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP021983_7

Consensus_repeat	Method
TGCGTCCCAAATAAAACTCTATGG	CRISPRCasFinder

spacers of NZ_CP021983_7

>7.1|1091453|39|NZ_CP021983|CRISPRCasFinder
GTCCCGCCCGGAAATAGAAAAGGACCGGCAAACAATGAT

CRISPR arrays and Neighbor proteins around NZ_CP021983_7

CRISPR arrays

The CRISPR arrays of NZ_CP021983_7

>merge|NZ_CP021983|7|1091429-1091515|CRISPRCasFinder
TGCGTCCCAAATAAAACTCTATGGGTCCCGCCCGGAAATAGAAAAGGACCGGCAAACAATGATTGCGTCCCAAATAAAAGTCTATGG

>NZ_CP021983|7|8|1091429-1091515|CRISPRCasFinder
TGCGTCCCAAATAAAACTCTATGG	GTCCCGCCCGGAAATAGAAAAGGACCGGCAAACAATGAT
TGCGTCCCAAATAAAAGTCTATGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_080806335.1|1089107_1091225_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|274350
NZ_CP021983.1|WP_080806328.1|1086351_1087104_+|aquaporin-family-protein	unknown	unknown	gnl|CDD|223653
NZ_CP021983.1|WP_080806331.1|1088371_1088614_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|225215
NZ_CP021983.1|WP_088429268.1|1100492_1102013_-|DUF697-domain-containing-protein	unknown	unknown	gnl|CDD|368297
NZ_CP021983.1|WP_080806447.1|1093804_1094338_-|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl|CDD|223854
NZ_CP021983.1|WP_080806324.1|1084965_1085565_-|glutathione-S-transferase	unknown	unknown	gnl|CDD|198315
NZ_CP021983.1|WP_088429266.1|1097250_1098672_-|pyruvate-kinase	unknown	unknown	gnl|CDD|223545
NZ_CP021983.1|WP_088429256.1|1087160_1087856_-|glutathione-S-transferase	unknown	unknown	gnl|CDD|183298
NZ_CP021983.1|WP_088429270.1|1102660_1105798_+|hypothetical-protein	unknown	unknown	gnl|CDD|226415
NZ_CP021983.1|WP_088429264.1|1095252_1097244_+|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl|CDD|223715
NZ_CP021983.1|WP_080806330.1|1088030_1088378_-|mRNA-degrading-endonuclease	unknown	unknown	gnl|CDD|182138
NZ_CP021983.1|WP_088429252.1|1083915_1084926_-|flavin-nucleotide-binding-protein	unknown	unknown	gnl|CDD|274926
NZ_CP021983.1|WP_088429260.1|1091789_1092188_-|rhodanese-like-domain-containing-protein	unknown	unknown	gnl|CDD|238089
NZ_CP021983.1|WP_080806351.1|1105810_1106062_+|DUF4242-domain-containing-protein	unknown	unknown	gnl|CDD|379428
NZ_CP021983.1|WP_080806340.1|1092319_1093705_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088429258.1|1088773_1088959_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088429262.1|1094732_1094984_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080806322.1|1083713_1083944_-|hypothetical-protein	unknown	unknown	gnl|CDD|379340
NZ_CP021983.1|WP_088429254.1|1085712_1086261_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP021983.1|WP_088431522.1|1098936_1100298_-|DUF697-domain-containing-protein	unknown	unknown	gnl|CDD|206646

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_080806335.1|1089107_1091225_-|tetratricopeptide-repeat-protein	gnl|CDD|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	9.90091e-31
NZ_CP021983.1|WP_080806328.1|1086351_1087104_+|aquaporin-family-protein	gnl|CDD|223653	COG0580, GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism].	4.14323e-73
NZ_CP021983.1|WP_080806331.1|1088371_1088614_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl|CDD|225215	COG2336, MazE, Growth regulator [Signal transduction mechanisms].	1.46372e-20
NZ_CP021983.1|WP_088429268.1|1100492_1102013_-|DUF697-domain-containing-protein	gnl|CDD|368297	pfam05128, DUF697, Domain of unknown function (DUF697). Family of bacterial hypothetical proteins that is sometimes associated with GTPase domains.	2.36444e-39
NZ_CP021983.1|WP_080806447.1|1093804_1094338_-|DNA-starvation/stationary-phase-protection-protein	gnl|CDD|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.94211e-64
NZ_CP021983.1|WP_080806324.1|1084965_1085565_-|glutathione-S-transferase	gnl|CDD|198315	cd03206, GST_C_7, C-terminal, alpha helical domain of an unknown subfamily 7 of Glutathione S-transferases. Glutathione S-transferase (GST) C-terminal domain family, unknown subfamily 7; composed of uncharacterized proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. GSTs also show GSH peroxidase activity and are involved in the synthesis of prostaglandins and leukotrienes. The GST fold contains an N-terminal thioredoxin-fold domain and a C-terminal alpha helical domain, with an active site located in a cleft between the two domains. GSH binds to the N-terminal domain while the hydrophobic substrate occupies a pocket in the C-terminal domain.	1.14317e-43
NZ_CP021983.1|WP_088429266.1|1097250_1098672_-|pyruvate-kinase	gnl|CDD|223545	COG0469, PykF, Pyruvate kinase [Carbohydrate transport and metabolism].	0
NZ_CP021983.1|WP_088429256.1|1087160_1087856_-|glutathione-S-transferase	gnl|CDD|183298	PRK11752, PRK11752, putative S-transferase; Provisional.	5.60011e-73
NZ_CP021983.1|WP_088429264.1|1095252_1097244_+|hybrid-sensor-histidine-kinase/response-regulator	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	9.37145e-56
NZ_CP021983.1|WP_080806330.1|1088030_1088378_-|mRNA-degrading-endonuclease	gnl|CDD|182138	PRK09907, PRK09907, endoribonuclease MazF.	1.63995e-39
NZ_CP021983.1|WP_088429252.1|1083915_1084926_-|flavin-nucleotide-binding-protein	gnl|CDD|274926	TIGR04025, hypothetical_protein, PPOX class probable FMN-dependent enzyme, DR_2398 family. Members of the PPOX family (see pfam01243) may contain either FMN or F420 as cofactor. This subfamily consists of proteins mostly from species that lack the capability to synthesize F420, and therefore most likely all bind FMN.	7.13204e-17
NZ_CP021983.1|WP_088429260.1|1091789_1092188_-|rhodanese-like-domain-containing-protein	gnl|CDD|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	3.92716e-17
NZ_CP021983.1|WP_080806351.1|1105810_1106062_+|DUF4242-domain-containing-protein	gnl|CDD|379428	pfam14026, DUF4242, Protein of unknown function (DUF4242). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 90 and 170 amino acids in length. There is a single completely conserved residue C that may be functionally important.	4.76725e-15
NZ_CP021983.1|WP_088429270.1|1102660_1105798_+|hypothetical-protein	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	2.69432e-35
NZ_CP021983.1|WP_080806322.1|1083713_1083944_-|hypothetical-protein	gnl|CDD|379340	pfam13701, DDE_Tnp_1_4, Transposase DDE domain group 1. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	1.49606e-08
NZ_CP021983.1|WP_088429254.1|1085712_1086261_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	5.43309e-12
NZ_CP021983.1|WP_088431522.1|1098936_1100298_-|DUF697-domain-containing-protein	gnl|CDD|206646	cd00880, Era_like, E. coli Ras-like protein (Era)-like GTPase. The Era (E. coli Ras-like protein)-like family includes several distinct subfamilies (TrmE/ThdF, FeoB, YihA (EngB), Era, and EngA/YfgK) that generally show sequence conservation in the region between the Walker A and B motifs (G1 and G3 box motifs), to the exclusion of other GTPases. TrmE is ubiquitous in bacteria and is a widespread mitochondrial protein in eukaryotes, but is absent from archaea. The yeast member of TrmE family, MSS1, is involved in mitochondrial translation; bacterial members are often present in translation-related operons. FeoB represents an unusual adaptation of GTPases for high-affinity iron (II) transport. YihA (EngB) family of GTPases is typified by the E. coli YihA, which is an essential protein involved in cell division control. Era is characterized by a distinct derivative of the KH domain (the pseudo-KH domain) which is located C-terminal to the GTPase domain. EngA and its orthologs are composed of two GTPase domains and, since the sequences of the two domains are more similar to each other than to other GTPases, it is likely that an ancient gene duplication, rather than a fusion of evolutionarily distinct GTPases, gave rise to this family.	7.53966e-42

Protein sequences

>NZ_CP021983.1|WP_080806335.1|1089107_1091225_-|tetratricopeptide-repeat-protein
MAGERGGSGFIQWLRQLAGGVTGGIGLVTSLVGLIQLFRGHSGLVSLLLLGLGIVLLWLACLYYARFWQPERRDASSSGFQPAPTDSQVQRQRQKKRRRKIVRRMAKVGLVLVPLLVIAGVSTWQYVERLPSQQVVIVVAEFDGPDVQNYRVTDTILRELRDATEEYDDVKVEALDEAITEQAGSDAARKLGEQQKASILIWGWYGKTETAVPISVNFEVLKPPEYLPEFGESASGTVQTAALAELNSFQLQTRLSAEMAYLTLFTLGMARYAAEDWSGAIDRFEAALLQTQEPLASLERHIALFYKGNAHFFDEDFNAAIAAYDAALKIEPDDHEALNNKGVALADLGRYEAAIAAYDAALNIKPDKHEALYNKGNVLYHLDRYEAAIAAYDAALNIKPDDHAALYNKGNALADLGRYQAAIAAYDAALNIKPDKHEALYNKGNALADLGRYEAAIAAYDAALNIKPDKHEALYNKGNALYHLGRYEAAIAAYDAALNIKPDLHEALNNKGNALADLGRYEAAIAAYDAALNIKPDKHETLYNKGVALADLGRYGAAIVAYDAALKIKPDYDAALHNKGVALAALGRYDAAIAAFDAALKIKPDDHVALNNKGNALTALGRYEQAIHALNAALDIEPNDPGSHFHLARCQALLGNTDEALDSLATLFRLAPDAGREAVAASRDFDSLGDHPRFQALMASDSPKQ
>NZ_CP021983.1|WP_088429258.1|1088773_1088959_-|hypothetical-protein
MTDLLLILGRWLLTGEAMLTDGAVALQTDTILQVRAWEWLRQQYPHLEVICRHRLSIKTAP
>NZ_CP021983.1|WP_080806331.1|1088371_1088614_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MVATVTKWGNSLALRIPQHIAKEIQLTEGAEVDLAVIDGNLVIKPRPRRRYSLEELIAAITPETLHSEVETGVAVGNEAW
>NZ_CP021983.1|WP_080806330.1|1088030_1088378_-|mRNA-degrading-endonuclease
MVNPAERYIPDRGHILYLDFNPTKGHEQRGHRPAFVLSPRSYNAKSTLALFMPITRQQKGYPFEVLLPPELQIQGVILVDQIKCLDWTARNVQFVEIVPDSLVEEVQAKIEPLIL
>NZ_CP021983.1|WP_088429256.1|1087160_1087856_-|glutathione-S-transferase
MIDLFTYTTPNGRKPSILLEELQLPYTVHAINIGQGEQFSPEFVAINPNSKIPAIVDRDHQLAVFESGAILIYLAEKTGKLLPTEAVARAQVMEWLMFQMASVGPMFGQLGHFRNAAPDPIPYAIERYRKETLRLLGVLDRQLADQPYIAGDYSIADIATFPWVAAVKTPYLDISLADFPWVSGWIDAMKARPAVQVGMNILKPAFKSDYGTVAPPQETRQALEMAQKQAA
>NZ_CP021983.1|WP_080806328.1|1086351_1087104_+|aquaporin-family-protein
MDPFYGEIIGTALLILLGNGVVANVVLEGTKAEASDWNTITLGWGMAVFVSVFSVAAISGAHLNPAVSLGLAVAGKFSWSILPVYVLGQFIGAAIGAMLVWLFYRPHLAKTRDCDRKLAVFCTTPAIRDRVSNFLCESMGTSVLVFSVLQLAKPTFGLGALDALPVGLLVLAIGLSLGGTTGYAINPARDLAPRIMHALLPIPGGKRDSDWPYAWVPVLAPLFGALLAAWLYLALGGEIRVDLPSVSEFF
>NZ_CP021983.1|WP_088429254.1|1085712_1086261_+|TetR/AcrR-family-transcriptional-regulator
MPKETYIPSLFGLFRQYGYDGATLAKISAATGLGKASLYHHFPDGKEEMVEAVLSYSDDWLQENVLTPLANEGTAQERLQKMCDRIDDLYAGGTQPCLLAILQAGTGRDVFHGQVNALLKRWIGAIARVLAQAGMDDRLAHQRGEDAIIAIQGALMLSQGLKDPSPFQRVIQALPEELCRQP
>NZ_CP021983.1|WP_080806324.1|1084965_1085565_-|glutathione-S-transferase
MITLYGHEMSGNSYKVRLLLELLQLDYDWAAVDLMQGEHKSPEYLALNPFGQVPLLIDGDMKLADAQAILVYLARQYGGEQWLPMDAVALAQVVRWLSITAGEVRQGPENARLYHLFGATSINIDRAQQKADQILTQLDKHLLGRTWLEFQRHTIADIAVFPYVALAPDGQVDLAPYSQVLTWIDRVKHLPGFISMAGL
>NZ_CP021983.1|WP_088429252.1|1083915_1084926_-|flavin-nucleotide-binding-protein
MTTGWTQPHSPFHAGEQAVQTRMGVRDKLEKLGRRVVRDYLADQHREFYHLLPFLIVGTLDHQGHPWASILTGPPGFITAPDPYHLRMATQPLFGSPLADHLTAGADIGILGILPENRRRNRSTGRISAVDDAGITVAIAQTFGNCPQYIQTRTMEVLPEVADPGQAKHIVQGERLDDAAKALISRSDTLFIATAYTPSQDSPAFGADASHRGGNPGFVRVEDDQTLIFPDFTGNFHFNTVGNILLNPSVGLLFIDFDTRDLLYLTGQADIIWEGEEVTAFLGAERFIRIHVEAWQRVAASLPLQFQFGEYSPMLQHSGSWEQMDATLAAKHLRCQ
>NZ_CP021983.1|WP_080806322.1|1083713_1083944_-|hypothetical-protein
MRPNIYDVNDHDDLRHEQLFGVVLGQLESDHPRCAPLAGKSTLNRLEQAMHVPGDLFDSRYVKMSLAPGDDCRQRR
>NZ_CP021983.1|WP_088429260.1|1091789_1092188_-|rhodanese-like-domain-containing-protein
MANVSEQIDAVKSNLTGPAPTLTELPPQASPQDLQARLNWGEPALTIIDVRDRTAYNQERIQGAISMPRAELLPMIQGSLESTRDIYIYGDNDDDTAAAAEQLRQAGFTRVVELKDGLAGWQAISAPTEGNA
>NZ_CP021983.1|WP_080806340.1|1092319_1093705_-|hypothetical-protein
MARVNWSTLSKRWNQGVTLLITLNVGLVLFNLSYVPLRGLYLQYVPTLVQAYDPLKGIEPHPQTQTYLETVATLRQTLATQGLEAQESEALLADLRQQSMTLIEENPFLIENQMASFAQLKRRMRGYMQTASAQNAFQRFWSQAYLNEVGWPTALAYFDRRIEPILARNYFRQTIATGQFVDFFWWVDGFFMAFFAGELLVRSLVVSRRQPGVSWLDAIARRWYELPLVLPFWRWLRILPMLVRLHRSGLANIEWLLSQITHEPAAYLSNRISQYLLVRLINQTQDSVQQGTLFTADETALQVPVGEPDKVNRILDRLTELVIYRVVPTLQPDLEAVLRHSLKQALTNSNLYDGLRQIPGIETMPASALDLLASYLAQATCDILVDSYDDEQGRVLLDQLNRDFRQALGEEIKGQETATELKQLLFDLLEEVKINYVQREKIHDPEATLAEVDTLQQRPSS
>NZ_CP021983.1|WP_080806447.1|1093804_1094338_-|DNA-starvation/stationary-phase-protection-protein
MRPINIGLSDEQRQGVIELLNQHLADAYLLLIKTKKYHWDVVGPQFRTLHELWEEHYQALTESIDDYAERIRALGGYPLGTVEGFLKHASLKEHPGDLPDANEMVGRLVVDHEQVIRNLRQAIDQCSDQFHDEGTADFLTGQLEAHEEMAWMLRSFIEGTGIEPSGYRPEVRPSVAR
>NZ_CP021983.1|WP_088429262.1|1094732_1094984_+|hypothetical-protein
MAASHPLKGLELLDCAKSNAEQGVAIAAHQCGYGSDIEGFARSLKRTCEDIGVDIESLGDLITPPDRQEGRGLDIAPDSTNIL
>NZ_CP021983.1|WP_088429264.1|1095252_1097244_+|hybrid-sensor-histidine-kinase/response-regulator
MAQSQILLLEDIAFDIETIRTALDSGGIESNMICVDNRQDFIAALQATSIDLVLADYALPNFDGLAALDIIRGQYPHIPFILVSGLMGEELAIETLKQGATDYVLKQRLGRLVPAVKRALNETAERRARYRAEQALQESEDRFRASVEIMLDCFGIYSAIRNTSRQIQDFRIEYLNTAACQQLGQDPWTVIGQRLSEQFPMYQAMGLVDAYAQVVETGQPLVQESLLYEDDQAEVLATALDVRAAKLGDSVVVTWRNITDRKLSEQERESLLAREQAAREEAEAASRVKDEFLATLSHELRTPLNAMQGWLQLLQRRRLDEGTATRALATIQRNVEALRRLIEDVLDVSRIIRGKLKLTVTPLDVAPVVLAATETILPAAEAKQIDLQTQLAATATLVLGDRNRLQQIIWNLLSNAIKFTPEGGRVDIRLEVLNHYVQIQVQDSGKGIEPEFLPHIFERFRQADSSTTRRHMGLGLGLAIVRHLVELHGGLVRADSPGLGQGATFTMLLPQLSQTSSDTWAEGNMASQAMASLKNCRILIVDDQADARELYTTFFKGLRANVKAVATATEALTLQDSFRPDVLVSDVCRPGMQGYELIQQIRQRYLIPAIALMQAAVPEEKRQVLAAGFQIYLSKPVEMQQLADAIAHLTYSDATTPGNQPSS
>NZ_CP021983.1|WP_088429266.1|1097250_1098672_-|pyruvate-kinase
MHLLPHRTKIVATIGPASSSRDTIQHMIRAGMSVARLNFSHGSYDDHAQRIRLLRQVAQEHDTPITLLQDLQGPKIRVGALAEDGMQLAAGKRLTLLPSDHATGLNQVTIDYPHLAADARPGMTILLDDGLLELQIEAVEPPAVHCRVIQGGPLRSRKGVNLPDLTLRLPSLTAKDREDLKFGLSQGVDMVSLSFVRRAEDVQALKQLLATHGAADVPVLAKIEKPQAIANLEAILAVCDAVMVARGDLGVEMRAEKVPMLQKRIIRACNLRKLPVITATQMLDSMIHNPRPTRAEASDVANAIIDGTDAVMLSGESAVGAFPVESVQMLGRIAADIEPELEFVNNPPAKTDETHALSEALNVIDKVLDLRCIVSFTASGYTAMIAAGERPRAPVIALTPNVKVYHRLNLVWGVKPILVDTPATSFEAMTQQADQYLCDRTYASPGDKVLIMGGIPAGISQGTNFIKIHTIGN
>NZ_CP021983.1|WP_088431522.1|1098936_1100298_-|DUF697-domain-containing-protein
MTRVQQSLRQTARRYQEHIQQPQGEATARQRQATIKTGIEQLTTLANRLEQPTLTVAVFGLVSRGKSAVINALLGQPVLQTGPLHGVTRWPRSVYWSPPVETVHSTNLPMQIELIDTPGLDEVDGQERADMAQTIASQADLILFVVSGDITRTEYQALTMLQASHKPILLVFNKTDLYPEMDRQAVYDALRRLWQQSQAEAPLALGLEQVVMVAAEPAPLQVRVEWPDGHSSHEWESPPPQIAPLRQAILTLVQHHGPALLALNALGQAQSLETKMVKTAMALHQPAAEQLIWQFAKYKALAVALNPIAVLDVLGGVMSDLILIRSLARLYGLSMTNYEAGRLWQAIVRSSGVVLLSELGSGLLLGVGKSAGAVTSVFDSSAGLTAWAGAMVAQASAAGYGTYAVGKAAQQYLERGGSWGPQGIRQTLQELLHQLDSDATTEHLRQELQSLLD
>NZ_CP021983.1|WP_088429268.1|1100492_1102013_-|DUF697-domain-containing-protein
MTLTRPILIGGLGLTAVLGLLNGLHDSLTDHATLLVLMGVGSGVWWWRRRRQQPSSPVVPSSPVDRAAVDRLLALTTEQLDTLTTEIREHLDPEDRGPWLSRVEGLRQQGTALAEDLDRQTLTLALLGDPGVGKSTLRHHLSETWLPSLATTVMLQEGTTTLPAEQDPDILLWVTATDLTDSALASLRHYQQLGHRLVLVFNKQDQYGPLDRATMQQQLHQHSQSLPETIPVVAVTAQPGPLKVRRHQPNGSVEEWLETPQPETTDLLEHLRELVQQQQQELVLATAMRQGQQLQRRVRDHLNQLRRQRAMPTVERLQWIAAATAFANPLPSLDVLATAAINGQLVMDLGRIYQQGFSWQQAKATATTLAKLTVQLGLVELSSQALTSFLKSHAATYVAGGVVQGLSAAYLTRLAGLSLIDHFEEQSGRGSEAAPLSVQSLSQRLRPLMKQSQQSDWFKDLVAEGLSRLHRPADAAPTPVALATASAEPINLPESLLCDQDNASTD
>NZ_CP021983.1|WP_088429270.1|1102660_1105798_+|hypothetical-protein
MSHTPDTCQKSTAGSILSLKLLGDFRLAYANELVTSVQTPRLQSLLAHLVLHRHAPQSRQHLAVCIWPDSTDSQARTNLRRELYHLRQALPDAKKFLDIRPNTLQWRPADSPFHLDAADFEAAVALAQQTQDVVIRQTALEKAISLYQGDLLPSCYDDWIIPERNQLRQTYVHALDTMIEYLQEQREYGAAIAYAHRRLTHDPLCEAAYRRLMQLHGLNGDRASALQVYHRCVEVLEAKLGVEPSPATCEVVERLQTWESKAKDQNLDNSKFKIQNSKSFHPPLIGRETECRTLRHWLTTENTEQLLLLTGEPGIGKTRLLDELRASVLAARGQVLQGRGFEAEMVRPYGAWIDALRSGPQATHRAAQAEAGDGLSVALDRLLSTAGNEPEALSDRAQLFDAVVERLLRLAADCGLTVVILDDLQWLDETSIALLHYASRLLRGSLVRFACATRPRALAQNAPAAGFIQALQRERCLQSIDLAPLNRAHTSELARTFHSPVDEERLFLDSGGNPLFALEIARSAHSDSAAGPGNLEVLIQARLQQLEPAARELLPWAAALGRSFRLTTLAQVADNSPMGLLAALEQLEQYGIIRPGTDSDPDFEDDIEYDFAHDMVRQVAYQRLSQPRRRWVHLQLAQALEHLSGKTDTLAGEIAHHAALGGNRTLAAATALRAAQRCLRLFAYAEASKLAQRGIQHCQKLKDEQRVALHLELLGVYVLAGVSRAQVPTLEQELQGLIAEAKTLKLKDTAAIGLEALIALSYDHGDLTGVHQHSLQAAETGRSTSPAMTARTLANSGSCLADIGRDMPQAEALLLEAQSLAARVGIELSDIPHGLGCVRRFAGDWAEARQLLATGWQQARREQDHWRESVCLLNLALVEFEAGTPGAALPYCQEMAIVADKIGGEGSEAAFAEGLSALAQYQLGHTDAAARLESALTTLRQIDAKRMLAFVLTAAAESDLQREHPETAIPRAEEALQVAQIVDYPSSIALAWAVLIRATVGIEPDSAKSPAEQLQALHRALDGSPLSARARRAVDSLNPMLAIEV
>NZ_CP021983.1|WP_080806351.1|1105810_1106062_+|DUF4242-domain-containing-protein
MVRLVLETTYDPPFTETDWDSANQRLFPCLELHNVRWIRSLVSGDRTRSICEFEAPDAESVRQSYRQAQVPFGRIWAAELQEP

Crispr_ID: NZ_CP021983_8

• CRISPR_ID: NZ_CP021983_8
• CRISPR_location: 1166486-1166561
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP021983_8

Consensus_repeat	Method
CCTTGCCGATGCGACGCGATCTAT	CRISPRCasFinder

spacers of NZ_CP021983_8

>8.1|1166510|28|NZ_CP021983|CRISPRCasFinder
TGCGCCTAACCGCAAATGAAATCCTGCG

CRISPR arrays and Neighbor proteins around NZ_CP021983_8

CRISPR arrays

The CRISPR arrays of NZ_CP021983_8

>merge|NZ_CP021983|8|1166486-1166561|CRISPRCasFinder
CCTTGCCGATGCGACGCGATCTATTGCGCCTAACCGCAAATGAAATCCTGCGCCTTGCCGATGCGACGCGATCTTG

>NZ_CP021983|8|9|1166486-1166561|CRISPRCasFinder
CCTTGCCGATGCGACGCGATCTAT	TGCGCCTAACCGCAAATGAAATCCTGCG
CCTTGCCGATGCGACGCGATCTTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_080806179.1|1174525_1175746_-|DUF790-domain-containing-protein	unknown	unknown	gnl|CDD|368530
NZ_CP021983.1|WP_080806192.1|1166823_1167069_-|hypothetical-protein	unknown	unknown	gnl|CDD|372577
NZ_CP021983.1|WP_080806205.1|1158167_1158872_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080806435.1|1162454_1163633_+|glycosyltransferase-family-1-protein	unknown	unknown	gnl|CDD|340831
NZ_CP021983.1|WP_080806180.1|1174105_1174477_-|response-regulator	unknown	unknown	gnl|CDD|381164
NZ_CP021983.1|WP_080806208.1|1155251_1157678_+|hypothetical-protein	unknown	unknown	gnl|CDD|349872
NZ_CP021983.1|WP_088429282.1|1167575_1168766_-|aminotransferase-class-V-fold-PLP-dependent-enzyme	unknown	unknown	gnl|CDD|184450
NZ_CP021983.1|WP_080806194.1|1163645_1166189_-|glycogen/starch/alpha-glucan-phosphorylase	unknown	unknown	gnl|CDD|376320
NZ_CP021983.1|WP_080806182.1|1172991_1174134_+|bifunctional-diguanylate-cyclase/phosphodiesterase	unknown	unknown	gnl|CDD|238923
NZ_CP021983.1|WP_080806186.1|1168806_1170657_-|ferrous-iron-transport-protein-B	unknown	unknown	gnl|CDD|223447
NZ_CP021983.1|WP_080806177.1|1175790_1176573_-|3-methyl-2-oxobutanoate-hydroxymethyltransferase	unknown	unknown	gnl|CDD|376814
NZ_CP021983.1|WP_080806198.1|1161333_1161936_-|lipase	unknown	unknown	gnl|CDD|238873
NZ_CP021983.1|WP_080806184.1|1170891_1171794_+|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|369881
NZ_CP021983.1|WP_080806200.1|1160901_1161312_-|RidA-family-protein	unknown	unknown	gnl|CDD|100011
NZ_CP021983.1|WP_080806429.1|1159803_1160814_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379326
NZ_CP021983.1|WP_080806203.1|1158871_1159690_+|hypothetical-protein	unknown	unknown	gnl|CDD|238910
NZ_CP021983.1|WP_088431530.1|1157719_1157950_+|DUF3796-domain-containing-protein	unknown	unknown	gnl|CDD|372251
NZ_CP021983.1|WP_080806228.1|1154800_1155211_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080806190.1|1167185_1167404_-|KTSC-domain-containing-protein	unknown	unknown	gnl|CDD|379296
NZ_CP021983.1|WP_088431532.1|1171860_1172921_+|IS630-family-transposase	unknown	unknown	gnl|CDD|315923

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_080806179.1|1174525_1175746_-|DUF790-domain-containing-protein	gnl|CDD|368530	pfam05626, DUF790, Protein of unknown function (DUF790). This family consists of several hypothetical archaeal proteins of unknown function.	0
NZ_CP021983.1|WP_080806192.1|1166823_1167069_-|hypothetical-protein	gnl|CDD|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	9.57289e-09
NZ_CP021983.1|WP_080806435.1|1162454_1163633_+|glycosyltransferase-family-1-protein	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	2.75822e-71
NZ_CP021983.1|WP_080806180.1|1174105_1174477_-|response-regulator	gnl|CDD|381164	cd19937, REC_OmpR_BsPhoP-like, phosphoacceptor receiver (REC) domain of BsPhoP-like OmpR family response regulators. Bacillus subtilis PhoP (BsPhoP) is part of the PhoPR two-component system that participates in a signal transduction network that controls adaptation of the bacteria to phosphate deficiency by regulating (activating or repressing) genes of the Pho regulon upon phosphorylation by PhoR. When activated, PhoPR directs expression of phosphate scavenging enzymes, lowers synthesis of the phosphate-rich wall teichoic acid (WTA) and initiates synthesis of teichuronic acid, a non-phosphate containing replacement anionic polymer. Members of this subfamily belong to the OmpR family of DNA-binding response regulators, which are characterized by a REC domain and a winged helix-turn-helix (wHTH) DNA-binding output effector domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	4.51053e-36
NZ_CP021983.1|WP_080806208.1|1155251_1157678_+|hypothetical-protein	gnl|CDD|349872	cd03875, M28_Fxna_like, M28 Zn-peptidase Endoplasmic reticulum metallopeptidase 1. Peptidase family M28; Endoplasmic reticulum metallopeptidase 1 (ERMP1; Felix-ina, FXNA or Fxna peptidase; KIAA1815) subfamily. ERMP1 is a multi-pass membrane protein located in the endoplasmic reticulum membrane. In humans, Fxna may play a crucial role in processing proteins required for the organization of somatic cells and oocytes into discrete follicular structures, although which proteins are hydrolyzed has not yet been determined. Another member of this subfamily is the 24-kDa vacuolar protein (VP24) which is probably involved in the formation of intravacuolar pigmented globules (cyanoplasts) in highly anthocyanin-containing vacuoles; however, the biological function of the C-terminal region which includes the putative transmembrane metallopeptidase domain is unknown.	2.09482e-70
NZ_CP021983.1|WP_088429282.1|1167575_1168766_-|aminotransferase-class-V-fold-PLP-dependent-enzyme	gnl|CDD|184450	PRK14012, PRK14012, IscS subfamily cysteine desulfurase.	0
NZ_CP021983.1|WP_080806194.1|1163645_1166189_-|glycogen/starch/alpha-glucan-phosphorylase	gnl|CDD|376320	pfam00343, Phosphorylase, Carbohydrate phosphorylase. The members of this family catalyze the formation of glucose 1-phosphate from one of the following polyglucoses; glycogen, starch, glucan or maltodextrin.	0
NZ_CP021983.1|WP_080806182.1|1172991_1174134_+|bifunctional-diguanylate-cyclase/phosphodiesterase	gnl|CDD|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	7.08171e-119
NZ_CP021983.1|WP_080806186.1|1168806_1170657_-|ferrous-iron-transport-protein-B	gnl|CDD|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	0
NZ_CP021983.1|WP_080806177.1|1175790_1176573_-|3-methyl-2-oxobutanoate-hydroxymethyltransferase	gnl|CDD|376814	pfam02548, Pantoate_transf, Ketopantoate hydroxymethyltransferase. Ketopantoate hydroxymethyltransferase (EC:2.1.2.11) is the first enzyme in the pantothenate biosynthesis pathway.	1.13474e-150
NZ_CP021983.1|WP_080806198.1|1161333_1161936_-|lipase	gnl|CDD|238873	cd01835, SGNH_hydrolase_like_3, SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	1.95751e-55
NZ_CP021983.1|WP_080806184.1|1170891_1171794_+|PAS-domain-S-box-protein	gnl|CDD|369881	pfam08447, PAS_3, PAS fold. The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya.	1.78319e-16
NZ_CP021983.1|WP_080806200.1|1160901_1161312_-|RidA-family-protein	gnl|CDD|100011	cd06154, YjgF_YER057c_UK114_like_6, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.	2.61244e-56
NZ_CP021983.1|WP_080806429.1|1159803_1160814_-|GNAT-family-N-acetyltransferase	gnl|CDD|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.5775e-29
NZ_CP021983.1|WP_080806203.1|1158871_1159690_+|hypothetical-protein	gnl|CDD|238910	cd01935, Ntn_CGH_like, Choloylglycine hydrolase (CGH)_like. This family of choloylglycine hydrolase-like proteins includes conjugated bile acid hydrolase (CBAH), penicillin V acylase (PVA), acid ceramidase (AC), and N-acylethanolamine-hydrolyzing acid amidase (NAAA) which cleave non-peptide carbon-nitrogen bonds in bile salt constituents. These enzymes have an N-terminal nucleophilic cysteine, as do other members of the Ntn hydrolase family to which they belong. This nucleophilic cysteine is exposed by post-translational prossessing of the precursor protein.	5.55012e-09
NZ_CP021983.1|WP_088431530.1|1157719_1157950_+|DUF3796-domain-containing-protein	gnl|CDD|372251	pfam12676, DUF3796, Protein of unknown function (DUF3796). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 120 amino acids in length.	0.000534346
NZ_CP021983.1|WP_080806190.1|1167185_1167404_-|KTSC-domain-containing-protein	gnl|CDD|379296	pfam13619, KTSC, KTSC domain. This short domain is named after Lysine tRNA synthetase C-terminal domain. It is found at the C-terminus of some Lysyl tRNA synthetases as well as a single domain in bacterial proteins. The domain is about 60 amino acids in length and contains a reasonably conserved YXY motif in the centre of the sequence. The function of this domain is unknown but it could be an RNA binding domain.	4.62833e-21
NZ_CP021983.1|WP_088431532.1|1171860_1172921_+|IS630-family-transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.97716e-29

Protein sequences

>NZ_CP021983.1|WP_080806194.1|1163645_1166189_-|glycogen/starch/alpha-glucan-phosphorylase
MTTEQTQSIQVEDDRSGLGIETLRRAIADNLFYLQGKWPEIATLNDFYMALANTVRDRLMPRWLNTIRNYRRSEVRVVAYLSAEFLLGPHLGIKLINLGIEELVRQAVADSGLALEDLLAQEEEPGLGNGGLGRLAACYMESLATLEIPAIGYGIRYEFGIFDQELRDGWQVEVTDKWLQYGNPWEIPRPESAVMVRFGGRTEAYTDDEGAYRVRWIPARVVKGVPYDTPIVGYYVNTTNTLRLWRAEAAESFNFQAFNQGDYYGAVDQKIYSENLTKVLYPNDEPLQGKQLRLEQQYFFVSCALQDMIRLHRGAGGDLRQFHQKFAVQLNDTHPAVAVAELMRLLVDEHRLPWDAAWEVSQSTFGFTNHTLLPEALEKWPLPLFGSLLPRHLEIIYEINQRFLDQARVHFLGDSQKLAQLSLIDESGERYVRMAHLACVGSHAINGVAELHSELLKQTVLKDFYQLWPQKFQNKTNGVTPRRWLLLCNPRLSQLITEHIGTDWVCQLEQLRQLEAYAEDREFQRQWRQIKRAVKQDLADHIQQTLNIAINPDSLFDIQVKRIHEYKRQHLNVLHIITLYNRIRRNPDIDIVPRTFIFGGKAAPGYIMAKLMIKVITSVAEVVNNDPQVCDRIKVVFLPDYNVTNSQPVYPAADLSEQISTAGKEASGTGNMKFSLNGALTIGTLDGANVEIRQAVGAENFFLFGLTIEEVQQLQESGYNPWDYYNRTPDLKEAINLINSGFFSHGNRELFKPLVDSLVYDDPYLLLADYSAYIDCQDTVGQRFRETDTWTRMSILNSARMGYFSSDRAIREYCQDIWHVTPISVQLKPYVQADAGLKVENWHPDVL
>NZ_CP021983.1|WP_080806435.1|1162454_1163633_+|glycosyltransferase-family-1-protein
MHIAWLGKKSPFCGNVTYGREITNALLERGHRVTFLHFAQSADAETEHPDCVEVSLPFLFKSQILTIPSPKSGKLLIEALRQLQPDLVHASLTLSPLDFRLPEICDQLGLPLVATFHPPFDRKVRSLTSGTQHLTYQLYTPCLANFDRVIVFSNLQRDLLVKLGVPEDTVAVIPNGVDPQKYSPGPSTIKSEVNAEQLFVYQGRVSPEKNVEALLKGWRQARLGSSCKLVIVGSGPLTASLKMFYGAEDNVTWLGFVADEQRRIEILRGADGFILPSLVEGLSLSLLEAMACGVACIATDVGADGEVLEGGAGIILDPQRVSSQLQTILPICRDQPEMLDLLGRKARQRVLDRYTLSDNISHLEALYTEVVTPVTPPAALLTPLNLPNGSSS
>NZ_CP021983.1|WP_080806198.1|1161333_1161936_-|lipase
MSQDSRICFLGDSFVNGTGDPTCLGWTGRVCAALAAAGRSITYYNLGIRGETSMALAQRWQGEATRRFAPGADNRLVFCFGTNDTTWERGRVRIDLADTLAHSRQILSIARTLAPVLLVSPPAIADPAQNQRTQRLCQGLQDLCADLSVPYIDEFMPLQQSVIWMTQVQAGDGAHPQAAGYEEWAQHILQHSVWQQWMTP
>NZ_CP021983.1|WP_080806200.1|1160901_1161312_-|RidA-family-protein
MPFDRQLVSSGTPWETSVGYARAVRIGPHVWVSGTTATDAQGGIVAPGDGYGQTLRILSNVEQALMQVGAALTDVVRTRLYVTDIAQWQAIGQAHGEVFGQIRPAATMVEVSRLITPEMVVEIEVDAFIQRAVEAL
>NZ_CP021983.1|WP_080806429.1|1159803_1160814_-|GNAT-family-N-acetyltransferase
MLLIGSCCRALSIAAAYCCGHQMPMSMLLVEPAAIQHLQALLLGPDALTHQFGLAIAPDINLSTTALAFSLRHLVEGKVWPRWWTHLFILNDSRLVIGYGGYKGNPDADGIVEIGYAIAPSYQRQGFATQAARILMERAFAAQVTCVQAHTLPQENPSTRVLRKLGMARVASLEHPEDGAIWRWERRDPLPLIRSAIPADAEAIHQLVMAVIIRDLHPELSSEGQQTLARIITPDSLRQRLQRGAKIWVAEEAENLVGVIEVTPQQHIKLFFVASHRRHRGIGRLLFEMVKHHTTGPITVNSSAYALPVYRRLGFLQHGPITSHHGITFYPLRYPR
>NZ_CP021983.1|WP_080806203.1|1158871_1159690_+|hypothetical-protein
MCSIFSRILDGQVIVGRNFDWIQLGDNLHFVPPTRLYGLTTYGLFLIEQFGSDRPLEGMNSQGLFMGMTGIHADNFSPRKHNDYPIRLDEFGAMRFVLERAATTPQAVAILDQAEIVPHGVEPYVRLQYFIVDRHGEFCVIAGQEQTVLKRLDAIPFAAITNFPLSLRDNVVCDRFATLQRALPSVIHVKEVMALVETVSTELTVYSCLYSLTQQTVSVCVERDFQSILNFSLDQEMAQGYGFYNFGQLKLMSPDRKDRFKDAQYEVQRGFA
>NZ_CP021983.1|WP_080806205.1|1158167_1158872_+|hypothetical-protein
MRAATRLQNLLIPALFIAAFLIIYITSIEVTLNRGDNQFVNRAWSWSQYGIGLWAFLVFLWKINKVKQHYIWVGLLYAAINLLASYQVWGILPLGIWSQTTIIFLCFVATCLLTQNRRRVRSSLVAFSLQKLIRSALIGVALSLPFAIINILLWQMSRLSSVMSWQSPLHAANRSLIAGISEEIIFRFFILSFFLQSLRKTLPRRWLVMIAFFFGIVPLRNRRTTLTELISGLD
>NZ_CP021983.1|WP_088431530.1|1157719_1157950_+|DUF3796-domain-containing-protein
MSNPQRKKFWIGFLGFLGFLGFLAFAQDAPPLLFYFTFFSFFSAFRYLREELKYLGLLGVVGFIVAILGVLGIISV
>NZ_CP021983.1|WP_080806208.1|1155251_1157678_+|hypothetical-protein
MRFPKWWPRLSRPSSRVGRGFVLVALLVLSVILALAQLVPPAPLSASATPTQFSAQRAMPHLEAIAHQSRYAGSPGHTAAREHLIDAIAALGLEPEVQSTTVVQRWPGATRFEVGTVQNVLVRLAGTASTGAIALDGHYDSGPTAPGAADCGGCVATLLETLRALRAGPPLQNDVIFVFADAEETGDLGAHAFVTQHPWNQDVRLAINFEATGNQGPSVLYSTNHNNQRLIAGFVSASPHPVAHSFASAFLHWLPMLRGGCDLEEFMDRGSAGLGFALAGNTTGYHTKLDNVQTFDRRSLQHQGSYALALVQYFGNQDLTTLQTSNTKSQSAVYFNVLPKVVVYYSTAWAMPLAAAVSLLYLGVVGLGLRRRQLSLKGLLVGAIVFGISAIAAVLLAALLWWGIKTANSNLQVTMVGHYRTLHYFVGLVCFTVALMAIAQLWLQKKLSLSNRIAGALLVWDGLMLLTSAQTPDISYLFTFPLLFSLLLLGWQLLDPRFRLGSWVHILALTLAALPGTLLLLPAMVTPNLAWMLRFEYASPLPFLALSLIFVVLLMGLLIPHVEVLTANPRQALRPSRSDWSRRWLLPGLLLLASGLIFSVATATSGFDADHPRPNLIAYELNVDSGEATWVSEDAQLDDWTAQFFPAQTPKTAYETFLGMRTQAFQAPAPIVPLAAPDVELLSDTVSGRDRRLHLRLTSPRQAVNLHGEIAAGGVITAATVNGQEMDLAPFPLEARDHLAFSYYNLPPDGIDLILTVQSAQPLQLTLRDTSYGPPQIPDQAIAPRPADKMPAAVSERDPTAVMKTFRL
>NZ_CP021983.1|WP_080806228.1|1154800_1155211_+|hypothetical-protein
MILKSGLLYFAIVFAVGFILGPIRVLWAVPRFGTRVGELMEMPFMLIAIILAALWVVRRLSVPPGLWTRLCMGLVALGFLLIAEFGAVLQLWGLSIAEYLANRDPVSGTIYILMLGVFAAMPWLVSRKKRGGHLSS
>NZ_CP021983.1|WP_080806192.1|1166823_1167069_-|hypothetical-protein
MAKQHDMSITPRRKPPRNPLPKADKQANRTLARLRIRGEHSIRRLKRFRIFAERYRNRRRRFGLRLHLLAGILNYEMGLPI
>NZ_CP021983.1|WP_080806190.1|1167185_1167404_-|KTSC-domain-containing-protein
MELQFVESSMIQAFGYDEKTETLLVIFNSGKTYQYSEVPKETYEGLLASDSKGSYMRNFVIDCYPYVLMKKR
>NZ_CP021983.1|WP_088429282.1|1167575_1168766_-|aminotransferase-class-V-fold-PLP-dependent-enzyme
MSRPIYLDAHATTPVDPQVVQAMLPFFTEHFGNPASITHAYGWEAEAAVKSARQRIAAAINATPEEMVFTSGATEANNLAIKGVAEAYFAQGRHLITVQTEHSAVLDPCRYLEALGFEVTYLPVRPDGLIDLAELEAAIRPDTILVSVMAANNEIGVLQPLAEIGQLCCRLRQGSGIPLLHSDAAQALGKLPLDVQAMGIDLMSLTAHKLYGPKGIGALYGRRRQPRVRLAPQLHGGGHERGMRSGTLYTPQIVGFAKAVELALETMTAEAERLQGLRQHLWSQLQPLPAVRLNGHPTRRLPGNLNVSVAGVDGQALLLGLRTIAAVSSGAACSSTSTAPSHVLKALGHSDELAYASLRFGIGRFNTTAEIDRVAKGAIATIQSLRQATDLSGYVR
>NZ_CP021983.1|WP_080806186.1|1168806_1170657_-|ferrous-iron-transport-protein-B
MTCHSPSTTSTTTTTTTRRVALLGMPNTGKSTLFNRLTGAAAAVGNWPGITVDLLQAPLSLPEPMAGQQVELVDLPGTYDLGGFSDDERVVRQFLENFPIDLVLVVINAAQVDRQLRLLLQVKALGLPVLAVFTMADEARHYGVEIDGEGLAEHLGLAVEIIDAKRGQGHRQVLAAMASILAGEPESYRIDTLSETLAAGAERLPQQVEQALAGRVQMPAQLTRTVTETLDRVLLHPVLGLPCFFLGMLGIFWLIWTLGLPAQDAMDWLAGQLQRGLLEPVLQPLPPIVQDLALNGIWNGVATVASFVPLIVLFFMLMAVLEDSGYLARSAYLMDALMARLGLDGRSFVLQMMGFGCNVPALMGTRIMRSHTLRLLTMLVIPFALCSARLQVFVFIIATVFPGGNGALVLFSLYVLSFGAAIGTAALFQGRFPNDDPFVLELPPYRLPTLTQVLRRGWQEVTTFLRRASRFIILGCVAVWTLTALPPGATGPETIGGHIGQWLSPVMHPIGIDPYLTLALIFGFVAKEVVLGSLAVIYGLNAAAVSGYIGDHVSFAQGYSFCLFCLLYTPCLTTLVTLLNESKSWRFTLLSVGFSLALAWLTSWSFYQSARLLNLA
>NZ_CP021983.1|WP_080806184.1|1170891_1171794_+|PAS-domain-S-box-protein
MRPHLSLIPTSFGLCLLGSSVSLLLLNLESWDGEQGPLSASVPLGTVIALIGITIVSMTWLSAWILSQQMIQLIRQLTEYLLQVQAGDCDRPMRGLIWSRDLVHELNRWSSLLVDILHAHYRIETDLRESEERYALALQGANDGIWDWDLRSNRMHYSSRWKTLLGYDEETIGASPEDWFSRIHPEDLLSVKVSLAAHLQGETPHFESEHRLLRGDGRYGWVLVRGLAVCDQQHQTNRIAGSLTDITARKQTEEQLRYEALHDSLTHLPNRTHLIQQLQQTLDTVRVHPQYLAAVLLLDL
>NZ_CP021983.1|WP_088431532.1|1171860_1172921_+|IS630-family-transposase
MNSFQLEHQQKVDNRAILSDFISSNPDSRELKRALAVKMALEGEPYFKITKFLGINKSFITYWKNRFEAQGIEGIKLGYQGSKSYLTPDDRTEIISWLRTRNYWNFDELVSYLDEHYDVIYKSKQSYYTLFSEAGISWKKSQKTNPKSDPALVKKKREEIQGFIRQNQFKIESGELIVLFLDECHLLWGDVCGYVWGKTDMRIEIPITNERIRQTYYGALNYQTKEFILHPYEKGNGENTVAFMKYLQEQNPGKQIALIWDGASYHKSQEIKDFLATVNHGKEETEWQFKCILFAPNSPEQNPVEDVWLQAKNSLRRFWRLCRSFPAVKYLFEFFIDHQKFDFSKIEEYSPCS
>NZ_CP021983.1|WP_080806182.1|1172991_1174134_+|bifunctional-diguanylate-cyclase/phosphodiesterase
MLQCLAQRLATCVRPNDFVARFGGDEFVILLNNLSSAAGVGQIARRIQTQLLQPLTLDGYDISVSASIGIVPVNATYCHPEDLLRDADTAMYEAKARGRSCEVIFDQSMHRRSMTVLQLEADLRRAIERQEFCLYYQPIYCLANGRCQGMEALVRWHHPERGLVSPSDFIPLAEETGLIVPIGEWVLQTACAQAKVWYDAGQELSMSVNLSARQLQDPQLPDRIARVLRQAGLPAHLLQLEVTESFAMADVHLTSQLLQQLRAMGMQIAIDDFGTSYSSLGYLRRFPVSVLKIDKSFVQDVGVSQDAGVIISAIIAMAHILDIKVIAEGVETERQLAFLRNQECDSIQGFLMGCPLPANQVEQCLECMESWAIAADAAVA
>NZ_CP021983.1|WP_080806180.1|1174105_1174477_-|response-regulator
MSTILIVDDSSTLREMIAGLLIKLGMTVTEAKDGVEAQQILQTNPPDLMVLDIIMPNMNGYELCRWAKNNPSTKDIPIVICSSKGEEFDRHWGMKQGADAYIAKPFRPSEMVETVKQLLRQRR
>NZ_CP021983.1|WP_080806179.1|1174525_1175746_-|DUF790-domain-containing-protein
MIHRYQGEAIQPKRLALDGPYLALAADLIECFRQHQGKSQGELNRHLQELEGENTDYRIQRGLAHILRSSFAHFDIVSPLEPSQLRQRVFTLAATTVPNPTQAQHHLAILAQQLSQELEREVTPADIRQGLYADLQENRILVECEAPTAAALLHRYNLSQVQGIFYKASQVVLNLHRNDPGEYKLMFRYLKLFRLMAYIEGDADHGFTITIDGPTSLFKPSTRYGLDMAKVLPALLHVSRWSLMATLQLRDRYSGNLRQHHYTLKSDCGLVSHYPPGKPYDSLLEQSFAKRWPAQSEWRLEREVDLIPIPGSVMIPDFRLVHQDGREFLLEIVGYWRPDYLRKKFAQVRQAGQVPLILAVSERLNLDKAGVRLQDIPVPIVWFKEKLQPKAVLQVLQGICDRTNSP
>NZ_CP021983.1|WP_080806177.1|1175790_1176573_-|3-methyl-2-oxobutanoate-hydroxymethyltransferase
MVVNVHQFKQWKRDGRAIVVLTAWDYMSGQIVVQAGADIVLVGDSLAMVALGYETTLPLTLEEMLHHAKAVRRAVDRVPLVVDMPFLSYQVSVAGAIHSAGRVLQETEATAVKVEGGHPAIAPTIAALVQVGIPVMGHVGLTPQSVNQFGGFRRQGTSAESAQRILEEAKAVEAAGAFCIVLEHIPAELAQQISQTLTIPTIGIGAGAHCDGQVLVTADVLGLSSWQPKFAKAYGNLRQSAIDAAHQFCEEVRTRRFPNP

Crispr_ID: NZ_CP021983_9

• CRISPR_ID: NZ_CP021983_9
• CRISPR_location: 1269698-1269795
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP021983_9

Consensus_repeat	Method
CTTAGGTTTCAGCCCTACACGCA	CRISPRCasFinder

spacers of NZ_CP021983_9

>9.1|1269721|52|NZ_CP021983|CRISPRCasFinder
TCCCTACACGGTTTTTCCCAACCCCTACACACCCTACACAACTCCTACACTA

CRISPR arrays and Neighbor proteins around NZ_CP021983_9

CRISPR arrays

The CRISPR arrays of NZ_CP021983_9

>merge|NZ_CP021983|9|1269698-1269795|CRISPRCasFinder
CTTAGGTTTCAGCCCTACACGCATCCCTACACGGTTTTTCCCAACCCCTACACACCCTACACAACTCCTACACTACTTAGGTTTCAGCCCTACACGCA

>NZ_CP021983|9|10|1269698-1269795|CRISPRCasFinder
CTTAGGTTTCAGCCCTACACGCA	TCCCTACACGGTTTTTCCCAACCCCTACACACCCTACACAACTCCTACACTA
CTTAGGTTTCAGCCCTACACGCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_080811641.1|1261550_1261868_-|thioredoxin	unknown	unknown	gnl|CDD|200072
NZ_CP021983.1|WP_080811639.1|1262784_1264560_-|hypothetical-protein	unknown	unknown	gnl|CDD|224563
NZ_CP021983.1|WP_080811634.1|1269869_1270088_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811648.1|1258115_1259393_-|glucosylglycerol-3-phosphatase	unknown	unknown	gnl|CDD|370536
NZ_CP021983.1|WP_088431543.1|1260172_1260742_-|NUDIX-hydrolase	unknown	unknown	gnl|CDD|239516
NZ_CP021983.1|WP_080811662.1|1275612_1276269_-|hypothetical-protein	unknown	unknown	gnl|CDD|271197
NZ_CP021983.1|WP_080811625.1|1272352_1273015_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088429321.1|1266914_1269038_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811644.1|1259834_1260020_+|DUF4278-domain-containing-protein	unknown	unknown	gnl|CDD|372912
NZ_CP021983.1|WP_088429319.1|1265133_1266864_+|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl|CDD|225387
NZ_CP021983.1|WP_080811627.1|1271450_1271981_-|ParA-family-protein	unknown	unknown	gnl|CDD|349760
NZ_CP021983.1|WP_080811629.1|1270988_1271303_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811637.1|1264602_1264959_-|stress-response-translation-initiation-inhibitor-YciH	unknown	unknown	gnl|CDD|236021
NZ_CP021983.1|WP_080811624.1|1273011_1273440_-|hypothetical-protein	unknown	unknown	gnl|CDD|274043
NZ_CP021983.1|WP_080811622.1|1273587_1274388_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811632.1|1270185_1270425_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811643.1|1260961_1261462_-|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	unknown	unknown	gnl|CDD|238269
NZ_CP021983.1|WP_080811621.1|1275320_1275572_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811631.1|1270448_1270844_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088431545.1|1262048_1262795_+|3-oxoacyl-[acyl-carrier-protein]-reductase	unknown	unknown	gnl|CDD|235500

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_080811648.1|1258115_1259393_-|glucosylglycerol-3-phosphatase	gnl|CDD|370536	pfam09506, Salt_tol_Pase, Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase). Proteins in this family are glucosylglycerol-phosphate phosphatases, with the gene symbol stpA (Salt Tolerance Protein A). A motif characteristic of acid phosphatases is found, but otherwise this family shows little sequence similarity to other phosphatases. This enzyme acts on the glucosylglycerol phosphate, product of glucosylglycerol phosphate synthase and immediate precursor of the osmoprotectant glucosylglycerol.	0
NZ_CP021983.1|WP_080811641.1|1261550_1261868_-|thioredoxin	gnl|CDD|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	1.73246e-39
NZ_CP021983.1|WP_080811639.1|1262784_1264560_-|hypothetical-protein	gnl|CDD|224563	COG1649, COG1649, Uncharacterized protein conserved in bacteria [Function unknown].	7.49881e-108
NZ_CP021983.1|WP_080811627.1|1271450_1271981_-|ParA-family-protein	gnl|CDD|349760	cd02042, ParAB_family, partition proteins ParAB family. ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the initiation of DNA replication. ParB regulates the ParA ATPase activity by promoting nucleotide exchange in a fashion reminiscent of the exchange factors of eukaryotic G proteins. ADP-bound ParA binds single-stranded DNA, whereas the ATP-bound form dissociates ParB from its DNA binding sites. Increasing the fraction of ParA-ADP in the cell inhibits cell division, suggesting that this simple nucleotide switch may regulate cytokinesis. ParA shares sequence similarity to a conserved and widespread family of ATPases which includes the repA protein of the repABC operon in Rhizobium etli symbiotic plasmid. This operon is involved in the plasmid replication and partition.	1.92918e-25
NZ_CP021983.1|WP_088431543.1|1260172_1260742_-|NUDIX-hydrolase	gnl|CDD|239516	cd03424, ADPRase_NUDT5, ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+, for its activity. It also contains a highly conserved 23-residue Nudix motif (GX5EX7REUXEEXGU, where U = I, L or V) which functions as a metal binding site/catalytic site. In addition to the Nudix motif, there are additional conserved amino acid residues, distal from the signature sequence, that correlate with substrate specificity. In humans, there are four distinct ADPRase activities, three putative cytosolic enzymes (ADPRase-I, -II, and -Mn) and a single mitochondrial enzyme (ADPRase-m). Human ADPRase-II is also referred to as NUDT5. It lacks the N-terminal target sequence unique to mitochondrial ADPRase. The different cytosolic types are distinguished by their specificities for substrate and specific requirement for metal ions. NUDT5 forms a homodimer.	5.34986e-50
NZ_CP021983.1|WP_080811662.1|1275612_1276269_-|hypothetical-protein	gnl|CDD|271197	cd01197, INT_FimBE_like, FimB and FimE and related proteins, integrase/recombinases. This CD includes proteins similar to E.coli FimE and FimB and Proteus mirabilis MrpI. FimB and FimE are the regulatory proteins during expression of type 1 fimbriae in Escherichia coli. The fimB and fimE proteins direct the phase switch into the 'on' and 'off' position. MrpI is the regulatory protein of proteus mirabilis fimbriae expression. This family belongs to the integrase/recombinase superfamily.	3.62302e-49
NZ_CP021983.1|WP_080811644.1|1259834_1260020_+|DUF4278-domain-containing-protein	gnl|CDD|372912	pfam14105, DUF4278, Domain of unknown function (DUF4278). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and viruses. Proteins in this family are typically between 58 and 136 amino acids in length. There is a single completely conserved residue R that may be functionally important.	5.32741e-12
NZ_CP021983.1|WP_088429319.1|1265133_1266864_+|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl|CDD|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	5.49806e-102
NZ_CP021983.1|WP_080811624.1|1273011_1273440_-|hypothetical-protein	gnl|CDD|274043	TIGR02225, Tyrosine_recombinase_XerD, tyrosine recombinase XerD. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerD, one of two closely related chromosomal proteins along with XerC (TIGR02224). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and with homologs of XerD on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerD, as some apparent XerD examples score below the trusted and noise cutoff scores. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	0.000185781
NZ_CP021983.1|WP_080811637.1|1264602_1264959_-|stress-response-translation-initiation-inhibitor-YciH	gnl|CDD|236021	PRK07451, PRK07451, translation initiation factor.	1.01024e-47
NZ_CP021983.1|WP_080811643.1|1260961_1261462_-|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	gnl|CDD|238269	cd00483, HPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is HPPK which catalyzes pyrophosphoryl transfer from ATP to 6-hydroxymethyl-7,8-dihydropterin (HP). The functional enzyme is a monomer. Mammals lack many of the enzymes in the folate pathway including, HPPK.	6.72597e-64
NZ_CP021983.1|WP_088431545.1|1262048_1262795_+|3-oxoacyl-[acyl-carrier-protein]-reductase	gnl|CDD|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	5.7913e-134

Protein sequences

>NZ_CP021983.1|WP_088429321.1|1266914_1269038_+|hypothetical-protein
MAPSSRWISGVSHSGKTTRLTDTLSHYGEVMAPALDQGRTLLVFAANGDNRITLAQRLIQATQGRYPMQTTTPSGFLMEEVSLFWPLLVTQLELPTQFPLRLRPETEQDLAMALWQPQLQTGALQVEGWLPDQTVRRGLDFLQLAAAAAIAPEDIGPMLADGIPPGFAPPTVWQTLAQALITWRNWCLQRGLLTYGIIGELYWRYLLPHPDYIARLPQRFCGVLADDVDEYPAVASLWFETLLAQGIPGCFTWNPDGQVRLGVGADPERLQQLQTHCQQHESLPQPVPPTLAYDWGPTIVQWVMDPLALPVPPPAIQTLQVTSRGDLLRRTAETIVAAIQAGRVAPTEVAIIAPGLDAIARYTLADILVSRGIPVEPLNEQRPLAASPLVRALLTLLTFVYPGLGRLMPREAVAEMLVVLSQTPEAEVGQAWFDRVQIDPVRAELIVDHCFVPHPEQPQLLPVSHFPRWDRLGYRATQAYEALLSWLQDQQQQRQQRLIPSVVAFLDRAIQQFLWRGNALPYDQLAALRELMETAQHFWEVDEQLRRLDPTSRQPPQEAIARFIQLLQRDTVTANPFPADALGTGPQGVTLATVFQYRLQRLSHRWQFWLDAGSPRWLTGTDALFGYPLFLSTWSGRSWTAVDIEQAHEQRLERILRDLLSRASERVVLCHSDLAVSGQEQTGPLLGLVNTAQPWGDEADNLAHLST
>NZ_CP021983.1|WP_088429319.1|1265133_1266864_+|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MGWGRVGWGLASSWIVITASGATAVAKSSPVPTGVQPAARYAQVDPSQDRFPDTDVPEPMPLQDGPALPTPSQPTAPPLPQEEQPPGEQTVYVEQIRVLGSTVFSPAELQAVVAPFAGQTLTLEGLTQAANAVTQLYLNRGYITSQAVVSDQVVADGILEIQVIEGALEAIQVEGTERLDDYVRSRIALAGLQPLNQFRLEDQLRLLQADPLFADITARLRAGSGQGQSILVVQVTEAPAFAANLVADNYSPRSVGQERIGAVLQYRNPVGWGDTLLASAYYSSEGGSKLYELSYRVPLNPMNGTLQLRAAPNEFRIVDEAFTGPGLNIEGSTEIYEAIVRQPLIRTPRQELALSLGFRYRDGETLINNLITGENRTSVVSFGQDYLRRDPQGAWAVRSQFRFGTGLFDATDGAEPDGQFFSWLGQLQRLQVLSPDQVLLLQADLQLANDSLLGSEQFFVGGGQSVRGYFQNQRSGDNGVRFSIEDRITLVREDDGRVLLQTTPFLDLGYVWAKDADINQLTDDNLLLGTGVGFILNMTPDLTTRLDIGVPLITLDEQAGDRPSRVQVHFNVNYRL
>NZ_CP021983.1|WP_080811637.1|1264602_1264959_-|stress-response-translation-initiation-inhibitor-YciH
MAQRKSSSKGSPCDRTVYSEFGGSNHAALARAQPDLPPEKQQLRVQASRKGRKGKTVTVISGFQQAPERLNALAKTLKGKCGSGGTVKDNTIEIQGDHADQLVQLLSQQGYPAKASGR
>NZ_CP021983.1|WP_080811639.1|1262784_1264560_-|hypothetical-protein
MFPFRSGMARLMGLVTLILTTFLVIGLAPDGTSRLSFPASMAGLPTPTSCAPTEQPVVDDATVTSNSAVTWAEFLEQLQRVLAAGPTPDWPPNAFEQALGVTAMTHVAAHYPRRYFEPTRPLLRAEAFMALAASLGIPPVITPNGILTTHFQDAAQIPAVTREGVAAALTQGLLAGQAEAGRLRPTEPITDAEVAILLCQAHALEARPPTQRPALGESIPAPTIPTTETRGVWLTNIDSEVLFSRQQLETALDRLAALNFNTVYPTVWNWGYTLFPSRVAAEVIGQQQRLYAERSTPALEAAQGRRDMLLELITLAHERGLAVIPWFEFGFMAPADYELARRHPEWFTQQGDGNPIAAEGQDLRRWLNPFHPQVQAFMLSLVNELMANYEVDGFQIDDHLGLPVEFGYDPYTVGQYQAEHDGRRPPTDSRDPEWLRWRADRISDFVGQLHRVVKGRRPEAVFSVAPNPYPFAYDHFLQDWPTWQRRGYVDEMIVQVYRQDLDRFVWELNRTPLQRVRSRIPTSIGILSGLKRRPIAMDWIRQQIDAIRDRTFAGMSFFFYETLWTSDTETFDQRYQALQAAFAAPARRPRP
>NZ_CP021983.1|WP_088431545.1|1262048_1262795_+|3-oxoacyl-[acyl-carrier-protein]-reductase
MAALQDQVAIITGASRGIGRAVAQTLAAEGAKVVVNYARSGDAAEAVVAQIHQQGGEGIALQADVSQTDQVDTLIQTTLDKWGRIDVLINNAGITRDTLLLRMKPADWQAVIDLNLTGVFLCTRAVAKLMLKQRQGRIVNIASVAGQMGNPGQANYSAAKAGVIGFTKTVAKELASRGVTVNAVAPGFIATDMTGDLSNAEEILKFIPLGRFGQPEEIAGMVRFLAADAAAAYITGQVFNVDGGMVMA
>NZ_CP021983.1|WP_080811641.1|1261550_1261868_-|thioredoxin
MVTKQKFQSFAELLAGSQQPLLVDFYATWCGPCQMMTGILEQVNAQLQGQLKVVKIDTDRYPQIASQHHIEALPTLVLFKQGQPVDRIEGVLAANQLIERLQPHL
>NZ_CP021983.1|WP_080811643.1|1260961_1261462_-|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase
MESVSCAIALGSNLGDSVAILQGALAALNALPQTELARQSRLYRTKPVGPPQPDYLNGCALVTTRLTPEVLLQQLLTIERRFGRIRRERWGPRQLDLDLLLWDDIVLQTPSLQIPHPRMHERAFVLVPLAEIAADWVDPRSGQTIQDLAQQVGAQDVWPLTLAASP
>NZ_CP021983.1|WP_088431543.1|1260172_1260742_-|NUDIX-hydrolase
MPIHQEPPQLLKQRLFYEGRKFNFEVNRLRLPNKAEGDWECIRHPGGALAVPVTPSGELVLVRQYRFALQGRLLEFPAGTVEPDEHPATTIQRELEEETGYRAHTWQPIGNFPLAPGYSDEIIYAFLATDLEHLDDGPQTDIDEDIEVILMTPEALTKAILSGEAVDAKSIASLFMVRPYLDALAPAET
>NZ_CP021983.1|WP_080811644.1|1259834_1260020_+|DUF4278-domain-containing-protein
MQLSYRGAHYEATIPNLEADNIEEIGRYRGATMTRKHFKVAQPHHGRVELTYRGVKYSHEV
>NZ_CP021983.1|WP_080811648.1|1258115_1259393_-|glucosylglycerol-3-phosphatase
MAIASSQPLHQQTYSLDHDRFEELLATTENLLIIQDLDGVCMGLVKDPRHRTIQPAYVEATQAFDGHFYVLTNGEHIGQRGVNGIIERAYGDAAQVRQRGLYLPGLAAGGVQWQTRQGELAHPGVSEAELAFLRSVPEQIRQRLRAFFRDHPTNLDDATLEPGIAASALENVASPTANLNTFHELLQDDPATYNALQHAMAALMEDLLAAAAAQGLADSFFVHYAPNHGRGNDGKETVWFSQGPESGTTDFQFMLRGAIKEAGVLALLNRYYAQRTGTYPLGPEFSVRQAPHDHEELVALVRDAFDPAQMPTLVGVGDTVTSQVFEVDGRPVAKRGGSDRNFLQLIQDIGRLYDNGNVVTYVDSSGGELKNRKALQIETVAGHLQVVAGPGDPRDSEDPLTLNVVFPGGYQQYCATFQAAARRRD
>NZ_CP021983.1|WP_080811634.1|1269869_1270088_+|hypothetical-protein
MILAIIWAEQGLAIRPSGIGLLLARGGIQPEEELESMRSLRTHRARSHPAGMPGTAPASLPPELQRQTAEDG
>NZ_CP021983.1|WP_080811632.1|1270185_1270425_+|hypothetical-protein
MNPALAAKFLYGTEPLTGAEYNDLTANPEMARLLSQARELRPQAQPPAQPQPAPQQQYTSEQLQQMDQTELAAIAFKSN
>NZ_CP021983.1|WP_080811631.1|1270448_1270844_+|hypothetical-protein
MAQNGDNLTPKQLAAVAELARGSSHQATVDATGVSHRQLSRWKAQPDFKEAILEAQRAIYGQSIAAIVTAMNTATTTLVEICENQEASDASRVSAARSILENGLKAFGQADLDRRVEEIEELFKSESAETT
>NZ_CP021983.1|WP_080811629.1|1270988_1271303_+|hypothetical-protein
MELTTRIEQLRQLKAASRRKREAMATGDRERIQQAIRVLRAQLPIAPVRSVESAAVAMAQLMRLERELYPHNADEVAELAVRYGVDPGEFIQVLQEKWHEKKGF
>NZ_CP021983.1|WP_080811627.1|1271450_1271981_-|ParA-family-protein
MFLTVSSFEGGVGKTTSTIHLAAFLAGLDGGESVLLVDGDENRSATSWSKRGELPFKVVAVDAAFRHIPKFKHVVIDTGARPSREDLEPLVEGCDLLILPTTPEAMAVDALVQTIDLLKEIGGDHYRVLFTMVHGNPKVQMASMAREALLSSWVEYRRGMAPAAAWKRVSGKQPEA
>NZ_CP021983.1|WP_080811625.1|1272352_1273015_+|hypothetical-protein
MSKSNKVLIIGASVALGVIAVVALGVGWMQFVSFRNEQAERAEAEEREARQEALNAISAECRDLRRIVNQTGDFMQEFEAEIQVFSDNASQVETLQDIKSAATEYTDAVDTVVVRLDGLTSELESKTYQDETLKGFQSEYTKVVKGFRTSLLEAGQAMNIIISTPSEAELPSRIDKSQEQTMAAVSSIEELSNTEDKLISDVNAYCEETNIERNELQTTN
>NZ_CP021983.1|WP_080811624.1|1273011_1273440_-|hypothetical-protein
MTSLANTTVFDPEVFSEAMRIATAMATIDRSQLWSEDELVAEFLDYKGKNSANTRAAYGRDLSHYRSFLQLQYQGDIGLSPGDTGAVDEYAAFLRSQVELEALAKSTDLDLVKQTLGHSSLAVTSNYLKANPQDSSGLHLVA
>NZ_CP021983.1|WP_080811622.1|1273587_1274388_+|hypothetical-protein
MLSGTIGIIIIMKSPKLLIASCSLLMLALTSCGLVPFSKTSSSQETPAAVAEEASSDEDQPIDDSFGEAVNTAMAAAEAAQTAQTADEWGNVAELWTKAIELMKAVPESSENYQTAQQKVEEYQRNVDYAADAAFAEKKVSSKYSEIHRFYGQPLMNVAENFGASLAQSGDRFTSEDETAEFYAESSNGESISYVEVGVKSLGPCQPNEAIGLSKTIMALGDVPSTNKVRETESSGYVTYRVEGLTVKTSCLYDGDWYTISVSADD
>NZ_CP021983.1|WP_080811621.1|1275320_1275572_-|hypothetical-protein
MADETILATFKIDKDTWHQFKARAKSRNSNASAVLKSLVYDYLDGKLDGLVESQGETLADAIAALSEQVKDLDRRLGKSSVAA
>NZ_CP021983.1|WP_080811662.1|1275612_1276269_-|hypothetical-protein
MNLDAQEPKVEQKGSVLPFPGVRPRLAKAGTSPNKGHEATGRTREYLTPAEIDQLLTAAKRTARNGHRNHMIVLMGYRHGLRVSEIADLRWADVDFQQGTILIRRLKGSHDSTHYLEGDELRGLRRLERENADSPFIFCSSTGAPLASSAISAMIKRTGKGLFRFPIHAHMLRHSCGYYLANKGVDTRTIQAWLGHANIRHTAHYTAMSPTQFKGLWS

Crispr_ID: NZ_CP021983_10

• CRISPR_ID: NZ_CP021983_10
• CRISPR_location: 1277480-1277627
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP021983_10

Consensus_repeat	Method
CACTCCCCCCCGCAGGTCGGGGGCGGG	CRISPRCasFinder

spacers of NZ_CP021983_10

>10.1|1277507|33|NZ_CP021983|CRISPRCasFinder
CAAGTCATGAGCAAGCCTGGGGCAAGTCAGGTC
>10.2|1277567|34|NZ_CP021983|CRISPRCasFinder
GGCGCAGTACGGGCTCAACACAGGCTCACAAAAC

CRISPR arrays and Neighbor proteins around NZ_CP021983_10

CRISPR arrays

The CRISPR arrays of NZ_CP021983_10

>merge|NZ_CP021983|10|1277480-1277627|CRISPRCasFinder
CACTCCCCCCCGCAGGTCGGGGGCGGGCAAGTCATGAGCAAGCCTGGGGCAAGTCAGGTCCACTCCCCCCCGCAGGTCGGGGGCGGGGGCGCAGTACGGGCTCAACACAGGCTCACAAAACACACTCCCCCCGCAGGTCGGGGGCGGG

>NZ_CP021983|10|11|1277480-1277627|CRISPRCasFinder
CACTCCCCCCCGCAGGTCGGGGGCGGG	CAAGTCATGAGCAAGCCTGGGGCAAGTCAGGTC
CACTCCCCCCCGCAGGTCGGGGGCGGG	GGCGCAGTACGGGCTCAACACAGGCTCACAAAAC
ACACTCCCCCCGCAGGTCGGGGGCGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_080811660.1|1277936_1278245_-|hypothetical-protein	unknown	unknown	gnl|CDD|366699
NZ_CP021983.1|WP_080811627.1|1271450_1271981_-|ParA-family-protein	unknown	unknown	gnl|CDD|349760
NZ_CP021983.1|WP_080811617.1|1277678_1277924_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811609.1|1280686_1282000_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811601.1|1283280_1283463_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811629.1|1270988_1271303_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811662.1|1275612_1276269_-|hypothetical-protein	unknown	unknown	gnl|CDD|271197
NZ_CP021983.1|WP_080811619.1|1276421_1277333_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811611.1|1280181_1280706_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811632.1|1270185_1270425_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811624.1|1273011_1273440_-|hypothetical-protein	unknown	unknown	gnl|CDD|274043
NZ_CP021983.1|WP_080811607.1|1281996_1282644_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811615.1|1278603_1279812_-|M23-family-peptidase	unknown	unknown	gnl|CDD|366703
NZ_CP021983.1|WP_080811625.1|1272352_1273015_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811613.1|1279768_1280185_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811621.1|1275320_1275572_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811622.1|1273587_1274388_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811631.1|1270448_1270844_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811605.1|1282647_1282965_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811603.1|1282968_1283205_-|hypothetical-protein	unknown	unknown	gnl|CDD|234760

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_080811624.1|1273011_1273440_-|hypothetical-protein	gnl|CDD|274043	TIGR02225, Tyrosine_recombinase_XerD, tyrosine recombinase XerD. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerD, one of two closely related chromosomal proteins along with XerC (TIGR02224). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and with homologs of XerD on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerD, as some apparent XerD examples score below the trusted and noise cutoff scores. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	0.000185781
NZ_CP021983.1|WP_080811615.1|1278603_1279812_-|M23-family-peptidase	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	3.37766e-10
NZ_CP021983.1|WP_080811627.1|1271450_1271981_-|ParA-family-protein	gnl|CDD|349760	cd02042, ParAB_family, partition proteins ParAB family. ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the initiation of DNA replication. ParB regulates the ParA ATPase activity by promoting nucleotide exchange in a fashion reminiscent of the exchange factors of eukaryotic G proteins. ADP-bound ParA binds single-stranded DNA, whereas the ATP-bound form dissociates ParB from its DNA binding sites. Increasing the fraction of ParA-ADP in the cell inhibits cell division, suggesting that this simple nucleotide switch may regulate cytokinesis. ParA shares sequence similarity to a conserved and widespread family of ATPases which includes the repA protein of the repABC operon in Rhizobium etli symbiotic plasmid. This operon is involved in the plasmid replication and partition.	1.92918e-25
NZ_CP021983.1|WP_080811662.1|1275612_1276269_-|hypothetical-protein	gnl|CDD|271197	cd01197, INT_FimBE_like, FimB and FimE and related proteins, integrase/recombinases. This CD includes proteins similar to E.coli FimE and FimB and Proteus mirabilis MrpI. FimB and FimE are the regulatory proteins during expression of type 1 fimbriae in Escherichia coli. The fimB and fimE proteins direct the phase switch into the 'on' and 'off' position. MrpI is the regulatory protein of proteus mirabilis fimbriae expression. This family belongs to the integrase/recombinase superfamily.	3.62302e-49
NZ_CP021983.1|WP_080811660.1|1277936_1278245_-|hypothetical-protein	gnl|CDD|366699	pfam01541, GIY-YIG, GIY-YIG catalytic domain. This domain called GIY-YIG is found in the amino terminal region of excinuclease abc subunit c (uvrC), bacteriophage T4 endonucleases segA, segB, segC, segD and segE; it is also found in putative endonucleases encoded by group I introns of fungi and phage. The structure of I-TevI a GIY-YIG endonuclease, reveals a novel alpha/beta-fold with a central three-stranded antiparallel beta-sheet flanked by three helices. The most conserved and putative catalytic residues are located on a shallow, concave surface and include a metal coordination site.	1.28446e-05
NZ_CP021983.1|WP_080811603.1|1282968_1283205_-|hypothetical-protein	gnl|CDD|234760	PRK00432, PRK00432, 30S ribosomal protein S27ae; Validated.	0.000593823

Protein sequences

>NZ_CP021983.1|WP_080811619.1|1276421_1277333_-|hypothetical-protein
MAAAIKQCRPYRIPKGFARWDELCTAMAVLINAVEGVDRATLLHGHRCGLWLSQNAPLYLVRTAVLRACEHTDIDFAADNKLLAGLNEPPIRTALFLLPSNALIAPDGGCVDWAVVHISDREHPELSQGEYELAGNTYRFPWLPHQNDYRYNWQWSTLDTRCSTLFSGFDIANDGSLIQGPPTLGTSELTGADLEFTHHVRNILLQLLLIASYQPSLISGEGNPPATPKGNPPRRSQTRYWQPRVISMPKSELRSPREGKRAGGGSGKREHWRRGHWRNQPVGAGRRSRRLIWIKPMIIGAEP
>NZ_CP021983.1|WP_080811662.1|1275612_1276269_-|hypothetical-protein
MNLDAQEPKVEQKGSVLPFPGVRPRLAKAGTSPNKGHEATGRTREYLTPAEIDQLLTAAKRTARNGHRNHMIVLMGYRHGLRVSEIADLRWADVDFQQGTILIRRLKGSHDSTHYLEGDELRGLRRLERENADSPFIFCSSTGAPLASSAISAMIKRTGKGLFRFPIHAHMLRHSCGYYLANKGVDTRTIQAWLGHANIRHTAHYTAMSPTQFKGLWS
>NZ_CP021983.1|WP_080811621.1|1275320_1275572_-|hypothetical-protein
MADETILATFKIDKDTWHQFKARAKSRNSNASAVLKSLVYDYLDGKLDGLVESQGETLADAIAALSEQVKDLDRRLGKSSVAA
>NZ_CP021983.1|WP_080811622.1|1273587_1274388_+|hypothetical-protein
MLSGTIGIIIIMKSPKLLIASCSLLMLALTSCGLVPFSKTSSSQETPAAVAEEASSDEDQPIDDSFGEAVNTAMAAAEAAQTAQTADEWGNVAELWTKAIELMKAVPESSENYQTAQQKVEEYQRNVDYAADAAFAEKKVSSKYSEIHRFYGQPLMNVAENFGASLAQSGDRFTSEDETAEFYAESSNGESISYVEVGVKSLGPCQPNEAIGLSKTIMALGDVPSTNKVRETESSGYVTYRVEGLTVKTSCLYDGDWYTISVSADD
>NZ_CP021983.1|WP_080811624.1|1273011_1273440_-|hypothetical-protein
MTSLANTTVFDPEVFSEAMRIATAMATIDRSQLWSEDELVAEFLDYKGKNSANTRAAYGRDLSHYRSFLQLQYQGDIGLSPGDTGAVDEYAAFLRSQVELEALAKSTDLDLVKQTLGHSSLAVTSNYLKANPQDSSGLHLVA
>NZ_CP021983.1|WP_080811625.1|1272352_1273015_+|hypothetical-protein
MSKSNKVLIIGASVALGVIAVVALGVGWMQFVSFRNEQAERAEAEEREARQEALNAISAECRDLRRIVNQTGDFMQEFEAEIQVFSDNASQVETLQDIKSAATEYTDAVDTVVVRLDGLTSELESKTYQDETLKGFQSEYTKVVKGFRTSLLEAGQAMNIIISTPSEAELPSRIDKSQEQTMAAVSSIEELSNTEDKLISDVNAYCEETNIERNELQTTN
>NZ_CP021983.1|WP_080811627.1|1271450_1271981_-|ParA-family-protein
MFLTVSSFEGGVGKTTSTIHLAAFLAGLDGGESVLLVDGDENRSATSWSKRGELPFKVVAVDAAFRHIPKFKHVVIDTGARPSREDLEPLVEGCDLLILPTTPEAMAVDALVQTIDLLKEIGGDHYRVLFTMVHGNPKVQMASMAREALLSSWVEYRRGMAPAAAWKRVSGKQPEA
>NZ_CP021983.1|WP_080811629.1|1270988_1271303_+|hypothetical-protein
MELTTRIEQLRQLKAASRRKREAMATGDRERIQQAIRVLRAQLPIAPVRSVESAAVAMAQLMRLERELYPHNADEVAELAVRYGVDPGEFIQVLQEKWHEKKGF
>NZ_CP021983.1|WP_080811631.1|1270448_1270844_+|hypothetical-protein
MAQNGDNLTPKQLAAVAELARGSSHQATVDATGVSHRQLSRWKAQPDFKEAILEAQRAIYGQSIAAIVTAMNTATTTLVEICENQEASDASRVSAARSILENGLKAFGQADLDRRVEEIEELFKSESAETT
>NZ_CP021983.1|WP_080811632.1|1270185_1270425_+|hypothetical-protein
MNPALAAKFLYGTEPLTGAEYNDLTANPEMARLLSQARELRPQAQPPAQPQPAPQQQYTSEQLQQMDQTELAAIAFKSN
>NZ_CP021983.1|WP_080811617.1|1277678_1277924_-|hypothetical-protein
MTTTSYTFARRTHNLPDDIDWRRTFEAPSYKQALQMAADYWFGGQKITDTHVDGNGVITLLSRAPGQQGWGGNVIGTLMEW
>NZ_CP021983.1|WP_080811660.1|1277936_1278245_-|hypothetical-protein
MRGCYLLHFRQPLDPSTPNRARHYIGYATDIDKRIKQHRKGRGSRFCAVAHERGIEFDVVCTWPNMGRDFERALKAQKNAPRLCWCCKLQTADPGKHRGVME
>NZ_CP021983.1|WP_080811615.1|1278603_1279812_-|M23-family-peptidase
MPTTGRCRMQGSPVRPIRPTFEELSPDLQWSLVNQWQRRDWSITAICVGLSSLLLAPVLVPSLNDRIAQGLNMVTRVTESADAVGDAIAPDFGEPIQAGEKIAGHPVTSGYGPRKAPCEGCSNQHRGVDLATPSGTTIYAPADKDKRVRVRCWRDGNGGGLVADIESESLPARKFQALHLSRCADGWHRGGQIIAKTGATGNGTGPHLDWRERDASGAHYHPANGPLIWALTGSKPVAPFSELSNTEKTCAIGAAEGTRDDNCDPTSAYYGHRDPGNGARNMGSFSYQHGASTPEEADQKQLARLQQAERDLQKRALEKWGQPLSKPAIAAALDIWNQSPDAGSRLIKHLPTHAPTPEQLVAARIAALNESRRELGGAPMNVPADQRRRVDQLLKHIRDDDR
>NZ_CP021983.1|WP_080811613.1|1279768_1280185_-|hypothetical-protein
MNRAKARNIAISSVPAALLILIADMAAPGWGRFINPVWLAKAQIAKLDRGWRELQPPGEDDPRLEACQQVLSENTVGNTQEQLRGALTGETEQIAVQWLGPPTCQLANDTYRWLTESGLSIDVIYADDGEVQDARLTR
>NZ_CP021983.1|WP_080811611.1|1280181_1280706_-|hypothetical-protein
MVGPKNNDVIDVEFSTVGGTGGGLAPYQSGGGIGRRRNAPRSNIADGGYFDATNKRKPLFFIDTATDDMGSLMAIRAWLSCLRHRPLQTMAVTGASVWLGLAGASGGLNLMRGDVLQCRGDIWNPVVSGCNLAAIVAPPTRAAAGGIHDVMLGTEEMGTPVESRPVIRAVPVDQ
>NZ_CP021983.1|WP_080811609.1|1280686_1282000_-|hypothetical-protein
MKPIYRLATAAGCGVASLGIATTAPQLSTLTADDLAAFANGQAVEVQYQRPGRLPAVALGLTALGFLGWWLMDQQPKPVTIADDSQAQPSGQTIEAPPGVEPPKRYIDVAGVLANNLHPTLITGNPRTGKGVVIAQAWRYVKQIRPEATIWVIQPKPHKNEMGYWDGCDRILPVMLEDHAPNDETIAQQLTDFIHEWRRQPTRPTVLVIDEGIKLDAMQPKWYRDFLIPTIKVEMSSGETDDRHLWMITQSPLVADLGLTGGNRAPLRLLAIETPESTEHLHSLMKSYRSIETKPDALVFQQSLSPKKAIFYHSDLGEWMPLLSYKVPSVTVGGTVQDLNRGSDMVQTLNRLYGKGYTSQGSGLNRFGSGGSDPPFSTPEILNRVRDCREMGLNQAQILLALWGVKKGGSQAYKDALDQYKTMIDILEAQDNGWSEK
>NZ_CP021983.1|WP_080811607.1|1281996_1282644_-|hypothetical-protein
MKEKDTRETPFTVPPEFRREIVRIDQPAPKWWQRQDVLIAGGIGSIAVLGLGIALFTGTGGQTYQPEPSMELDKDAIVAGAESSTEELIYQSSEQLQAFREQLLSQEARRYLLEAERQATDPEASCFSQSVHCALDQFARDAIASIERAKADRDWQQMLGAVSRVQAIELARQSVAPVEPEANLSQLAIQNLVESRQRLRSAEAESKAWEVREQP
>NZ_CP021983.1|WP_080811605.1|1282647_1282965_-|hypothetical-protein
MMQCLTSFFHSNAVAQLETLYGSKLQKMPTPERLALIAILAEAAYMVTMDGHSEYLHVIAENNGYSFTSHPRLLQLLAQLDSELNGASDAVRLIEGIASLMPTGG
>NZ_CP021983.1|WP_080811603.1|1282968_1283205_-|hypothetical-protein
MLTAHDIREFAARIQGNSPELSRDAALVQAVDMLANLETALAAYGRANPLCPQCSGHYLKRLSCGRCGGSGHVSAVEG
>NZ_CP021983.1|WP_080811601.1|1283280_1283463_-|hypothetical-protein
MQLIEIRRRLEDLTEFGAPAPSPSEWAALKRAWATLKPQTLPSYHPVIDDRIALVESLHR

Crispr_ID: NZ_CP021983_11

• CRISPR_ID: NZ_CP021983_11
• CRISPR_location: 1482357-1482438
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: WYL,PD-DExK

Consensus repeat of NZ_CP021983_11

Consensus_repeat	Method
GGACTCCGGCTTTGAGCAAACCCGCCAA	CRISPRCasFinder

spacers of NZ_CP021983_11

>11.1|1482385|26|NZ_CP021983|CRISPRCasFinder
CGAACCGCCGAACTGCAGCAGACCAT

CRISPR arrays and Neighbor proteins around NZ_CP021983_11

CRISPR arrays

The CRISPR arrays of NZ_CP021983_11

>merge|NZ_CP021983|11|1482357-1482438|CRISPRCasFinder
GGACTCCGGCTTTGAGCAAACCCGCCAACGAACCGCCGAACTGCAGCAGACCATGGACTCCGGCTTTGAGCAAACCCGCCAA

>NZ_CP021983|11|12|1482357-1482438|CRISPRCasFinder
GGACTCCGGCTTTGAGCAAACCCGCCAA	CGAACCGCCGAACTGCAGCAGACCAT
GGACTCCGGCTTTGAGCAAACCCGCCAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_088429375.1|1492449_1493718_+|toll/interleukin-1-receptor-domain-containing-protein	unknown	unknown	gnl|CDD|379328
NZ_CP021983.1|WP_088431555.1|1473184_1474897_-|ATPase	unknown	unknown	gnl|CDD|370720
NZ_CP021983.1|WP_080814266.1|1483018_1483639_+|UPF0016-domain-containing-protein	unknown	unknown	gnl|CDD|225030
NZ_CP021983.1|WP_080813546.1|1493814_1494435_+|hypothetical-protein	PD-DExK	mkCas0061_PD-DExK_CAS-I:CAS-III	unknown
NZ_CP021983.1|WP_080814247.1|1487860_1488586_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088429369.1|1475593_1477600_-|hypothetical-protein	unknown	unknown	gnl|CDD|238121
NZ_CP021983.1|WP_080813551.1|1489701_1491072_-|IS4-family-transposase	unknown	unknown	gnl|CDD|376573
NZ_CP021983.1|WP_088429367.1|1470880_1473037_-|glycine--tRNA-ligase-subunit-beta	unknown	unknown	gnl|CDD|234925
NZ_CP021983.1|WP_088429373.1|1492044_1492227_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080814232.1|1464495_1465749_+|glycosyl-transferase	unknown	unknown	gnl|CDD|340851
NZ_CP021983.1|WP_080813553.1|1488578_1488971_-|hypothetical-protein	unknown	unknown	gnl|CDD|375612
NZ_CP021983.1|WP_088429363.1|1467257_1469507_+|1,4-alpha-glucan-branching-protein-GlgB	unknown	unknown	gnl|CDD|235445
NZ_CP021983.1|WP_088429371.1|1485073_1486255_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|224370
NZ_CP021983.1|WP_080814239.1|1480144_1481071_+|TIGR01777-family-protein	unknown	unknown	gnl|CDD|187553
NZ_CP021983.1|WP_080814244.1|1483646_1485035_-|phosphodiesterase	unknown	unknown	gnl|CDD|225914
NZ_CP021983.1|WP_088429365.1|1469503_1470877_-|UDP-N-acetylmuramoyl-L-alanine--D-glutamate-ligase	unknown	unknown	gnl|CDD|235059
NZ_CP021983.1|WP_080814233.1|1466492_1466996_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NZ_CP021983.1|WP_080814264.1|1479749_1480148_+|photosystem-II-reaction-center-protein-Psb28	unknown	unknown	gnl|CDD|367722
NZ_CP021983.1|WP_080814246.1|1486906_1487632_-|TIGR03985-family-CRISPR-associated-protein	WYL	mkCas0075_WYL_CAS-I:CAS-III	gnl|CDD|274901
NZ_CP021983.1|WP_080814262.1|1465765_1466110_-|glutaredoxin-3	unknown	unknown	gnl|CDD|274017

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP021983.1|WP_080813546.1|1493814_1494435_+|hypothetical-protein	PD-DExK	mkCas0061_PD-DExK_CAS-I:CAS-III	1.9e-58	192.0	0.1
NZ_CP021983.1|WP_080814246.1|1486906_1487632_-|TIGR03985-family-CRISPR-associated-protein	WYL	mkCas0075_WYL_CAS-I:CAS-III	1.8e-104	345.0	0.4

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_088429375.1|1492449_1493718_+|toll/interleukin-1-receptor-domain-containing-protein	gnl|CDD|379328	pfam13676, TIR_2, TIR domain. This is a family of bacterial Toll-like receptors.	6.06587e-15
NZ_CP021983.1|WP_088431555.1|1473184_1474897_-|ATPase	gnl|CDD|370720	pfam09818, ABC_ATPase, Predicted ATPase of the ABC class. Members of this family include various bacterial predicted ABC class ATPases.	0
NZ_CP021983.1|WP_080814266.1|1483018_1483639_+|UPF0016-domain-containing-protein	gnl|CDD|225030	COG2119, COG2119, Predicted membrane protein [Function unknown].	5.69867e-44
NZ_CP021983.1|WP_088429369.1|1475593_1477600_-|hypothetical-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	1.90542e-100
NZ_CP021983.1|WP_080813551.1|1489701_1491072_-|IS4-family-transposase	gnl|CDD|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	2.33661e-07
NZ_CP021983.1|WP_088429367.1|1470880_1473037_-|glycine--tRNA-ligase-subunit-beta	gnl|CDD|234925	PRK01233, glyS, glycyl-tRNA synthetase subunit beta; Validated.	0
NZ_CP021983.1|WP_080814232.1|1464495_1465749_+|glycosyl-transferase	gnl|CDD|340851	cd03825, GT4_WcaC-like, putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.	2.68878e-137
NZ_CP021983.1|WP_080813553.1|1488578_1488971_-|hypothetical-protein	gnl|CDD|375612	pfam18182, mCpol, minimal CRISPR polymerase domain. Minimal version of the CRISPR polymerase domain. Predicted to generate cyclic nucleotides, potentially sensed by CARF domains which in turn activate various effector domain including HEPN RNases, CARF sensor and effectors are found in conserved genome contexts. Part of a broader class of conflict systems reliant on the production of second messenger nucleotide or nucleotide derivatives. Implicates CRISPR polymerase of the Type III CRISPR/Cas systems in a nucleotide synthetase functional role.	4.51937e-25
NZ_CP021983.1|WP_088429363.1|1467257_1469507_+|1,4-alpha-glucan-branching-protein-GlgB	gnl|CDD|235445	PRK05402, PRK05402, 1,4-alpha-glucan branching protein GlgB.	0
NZ_CP021983.1|WP_088429371.1|1485073_1486255_-|aldo/keto-reductase	gnl|CDD|224370	COG1453, COG1453, Predicted oxidoreductases of the aldo/keto reductase family [General function prediction only].	4.02507e-151
NZ_CP021983.1|WP_080814239.1|1480144_1481071_+|TIGR01777-family-protein	gnl|CDD|187553	cd05242, SDR_a8, atypical (a) SDRs, subgroup 8. This subgroup contains atypical SDRs of unknown function. Proteins in this subgroup have a glycine-rich NAD(P)-binding motif consensus that resembles that of the extended SDRs, (GXXGXXG or GGXGXXG), but lacks the characteristic active site residues of the SDRs. A Cys often replaces the usual Lys of the YXXXK active site motif, while the upstream Ser is generally present and Arg replaces the usual Asn. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	9.84021e-139
NZ_CP021983.1|WP_080814244.1|1483646_1485035_-|phosphodiesterase	gnl|CDD|225914	COG3379, COG3379, Uncharacterized conserved protein [Function unknown].	8.15308e-129
NZ_CP021983.1|WP_088429365.1|1469503_1470877_-|UDP-N-acetylmuramoyl-L-alanine--D-glutamate-ligase	gnl|CDD|235059	PRK02705, murD, UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase.	0
NZ_CP021983.1|WP_080814233.1|1466492_1466996_+|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	5.40488e-17
NZ_CP021983.1|WP_080814264.1|1479749_1480148_+|photosystem-II-reaction-center-protein-Psb28	gnl|CDD|367722	pfam03912, Psb28, Psb28 protein. Psb28 is a 13 kDa soluble protein that is directly assembled in dimeric PSII supercomplexes. The negatively charged N-terminal region is essential for this process. This protein was formerly known as PsbW, but PsbW is now reserved for pfam07123.	5.07519e-41
NZ_CP021983.1|WP_080814246.1|1486906_1487632_-|TIGR03985-family-CRISPR-associated-protein	gnl|CDD|274901	TIGR03985, hypothetical_protein_sll7078, CRISPR-associated protein, TIGR03985 family. Members of this protein family belong to CRISPR-associated (Cas) gene clusters. The majority of members are Cyanobacterial.	5.5375e-116
NZ_CP021983.1|WP_080814262.1|1465765_1466110_-|glutaredoxin-3	gnl|CDD|274017	TIGR02181, GRX_bact, Glutaredoxin, GrxC family. Glutaredoxins are thioltransferases (disulfide reductases) which utilize glutathione and NADPH as cofactors. Oxidized glutathione is regenerated by glutathione reductase. Together these components compose the glutathione system. Glutaredoxins utilize the CXXC motif common to thioredoxins and are involved in multiple cellular processes including protection from redox stress, reduction of critical enzymes such as ribonucleotide reductase and the generation of reduced sulfur for iron sulfur cluster formation. Glutaredoxins are capable of reduction of mixed disulfides of glutathione as well as the formation of glutathione mixed disulfides. This family of glutaredoxins includes the E. coli protein GrxC (Grx3) which appears to have a secondary role in reducing ribonucleotide reductase (in the absence of GrxA) possibly indicating a role in the reduction of other protein disulfides. [Energy metabolism, Electron transport].	1.64478e-43

Protein sequences

>NZ_CP021983.1|WP_080814239.1|1480144_1481071_+|TIGR01777-family-protein
MKVAITGATGFVGSRLVKRLQEQGHDSLVLTRDASKGRRVFPTSAFPRVQVVAYEPLQSGAWQDAIAGCDGVVNLAGAPISERWTPEHKQAMLNSRQIGTAKVVEAIANAEPKPNVLVNASAIGYYGTSETARFDETSAPVEDDFLSQVCRAWEAEAHKVKEAGVRLVILRFGIVLGMGGAIARMVPPFRLFAGGPIGSGRQWFSWIHREDLVSLILKALSEDTMAGIYNATTPHPVRMAELCHALGEVLNRPSWLPVPDFVLEALLGDGAKVVLEGQQVLPKRTEASGFTFQYPRVKAALQEILTDS
>NZ_CP021983.1|WP_080814264.1|1479749_1480148_+|photosystem-II-reaction-center-protein-Psb28
MTVSPTLEFFEGIYEDLSNVSLRQNRGTGVRSAKLIFEHMEAIEQFKSFRRQFSKALKLTDEEGIITVEPSGIKFIFGGPEGDDLVRVECLLEIDRDDHWQRFMRFMHRYADAHGMAYGESNPDAIQGSKPS
>NZ_CP021983.1|WP_088429369.1|1475593_1477600_-|hypothetical-protein
MLCCLNPQCPLPSNPRTAERCQGCGHPLVKRLRGRYIPIKLLGQGGFGRTFLGLDTDRLNSPCVIKQFAPQTQGTKSFDKAVKLFEQEAMRLHDLGEHPQIPTLLAYFAHDHYLYLVQQSIEGTTLYQELQERGAYDGQQVRQLLLDLLPVLQFIHHQGVIHRDITPTNILRRQQDGKAILIDFGVAKQFSEAVTPQPGTRIGTEGYSPIEQLRGGHAYPASDLYSLGVTCLHLLTNRKPEDLYDPLQGQWQWRQILQAAGRSIDPPLAQVLERLVQDLVGDRYQSAQDALRDLQGNGAWQGVVPGWVRQHPAGPISSPPQPPSSPPSEPPEPSEPPSTARPATTKPQTSSPPPTSRPQSSGRRPRSGTPRSRGWHCVRTVVGHRSWVMAVAFNPKTPALVSGSLDDTIRVWHLPSGKEFYSLEAHPRGVNDVVISRGGQVMASCGDDHTVRVWNLAQGKVLHTLTGHLRDVMSVAMGQRGFLLASGGEDRSLMLWKLDQGRHLKTLRGTAGIIKAVAMTADEQTLVSGGLDNQVRLWDIATGTLVRTLSGHLHSVNDLAISRDDKLIASASKDGTVRLWELATGTLLQTLAEHTQDVNGVAIAPDSRTLVSGSNDGTVKLWDLQTGQCLYSLSGHTGAVQAVAIHSSGRLIASASTDKTIRLWKWTG
>NZ_CP021983.1|WP_088431555.1|1473184_1474897_-|ATPase
MATLDSALRQQLHRLDGQSYKAYKSIRGTYEFPDFTLHIDYVQGDPFAAPSQVRLQVPRQTARFPAELYSSPVRAVALADYLTRQVYQVAQQLKSNRGSGKSGLIAIAPPSQAILARTAAQVRDGDLEIRCTVGLPAFGRRIAGRQAAELLCDDLPDILDQALCYDVLDAAALQRHVDTAEDADWLRQQLPQRDLVAFIADGARLPRRSGIDERPLEAEVIPFRSPDSLRVSVDCPHAGTITGMGIPSGITLIVGGGYHGKSTLLRAIETGIYAHIPGDGREQVVCLPAAVKVRAEDGRSVSGVDISPFIKNLPQERSTHAFSTTNASGSTSQAANIMEAVEAGAQALLVDEDTSATNFMIRDRRMQALIAKDREPITPFIDKVRQLYDDYGISTVLVMGGSGDYFDVADTVIALDNYEPREVTAQAQAIARQYVTERQREGGEHFGPITPRVVLPQGIDPSQGRKPVSLKVRQVDQVRFGREDIDLSAVEQLVEPGQVRAMAAAMVYGRQFMDGQRSLAEILSAIMADLDRDGLDCLDDRVSGDLVRFRPQDLAAALNRLRTLTIQPRE
>NZ_CP021983.1|WP_088429367.1|1470880_1473037_-|glycine--tRNA-ligase-subunit-beta
MATFLLEVGTEELPASFVEDAINQWRGSIASALAEELLTPAAVTVYGTPRRLAVVVAGLPERQPDRTDEVKGPPAQAAFQDGQPTRAAEGFARSRGVAVADLEVRDTDKGPFVFVTQSIAGRPAADILPEQVPQWIFGLEGKRFMRWGDGDLRFPRPIRWVVALLDDQVLPFSLENGSEVCPCDRISPGHRVLHPDPVVIAQASTYRETLNQAYVDVDPVSRADHIYQQLQAAASRVNGVPIIAAALLQEVTHLVEWPTAVVGKFDPAFLELPPEVITMEMESHQRYFPVRPNDGSAPLLPYFITVSNGDPAKADIIAAGNARVIRARLSDGKFFFDADRAIALETFSKRLHQVTFEERLGSMADKVDRIVAIADHIATQLSLAAPERQVIQRAAQLCKADLVTQMVGEFPELQGIMGEKYARHQGEADAVAVAIAEHYLPRGADDPLPQTLAGQVVGMADRLDTLVGIFSLGQLPSGSSDPFALRRAANAIVNVTWTAELPINLEQLLVTVIADFTANPNLTVAQPKELEQQLQDFFLQRIRTLLQDELAIDYDLVNAVLGDADADYAQRMLSDLLDARDRARFLHAMRSDGTLERIYETVNRATRLAAQGDLDTDILDPTPVVDPDQFQQPSEQAFLATLQTLLPQTQAAQAQRDYSQLVAGLEQATPVVSRFFDGPDSVLVMAEDAAIRRNRLNLLGLLRNHARVLADFGAIVKS
>NZ_CP021983.1|WP_088429365.1|1469503_1470877_-|UDP-N-acetylmuramoyl-L-alanine--D-glutamate-ligase
MNNAHVIGLGRSGIAAARLLHQDGWHVVLSDRNPAPRWLDQQSALETAGITVRLGYSFDPSEAVNLVVVSPGVPWDSPALIAAREQGLEVIGEMELAWRFLKDRPWVGITGTNGKTTTTALTAAIFQAAGFRAPACGNIGYAACELALSDQVPDWVIAEVSSYQIEAAATLAPQIGLWTTFTPDHLQRHYSLDNYFAIKASLLHRCEARVFNGDDPFLRRRIPDHFSQGYWTSIAGKVPLTSAPTHGSGQATTGPITYLEGGWVICQGQPIVAVDAFQMVGQHNWQNLLLAVTAAHLADIAPAAIAAAVANFSGVPHRLEHICTWQSIDFINDSKATNYDAAAVGLQSVTAPVVLIAGGDAKPGDDQAWLQLIQKKVATVLLIGTAAPDLAHRLDEVGYTAYEIVDTMKRALVRARDLAPAQQARTVLLSPACASFDQYPDFEVRGDHFRRLCLEHC
>NZ_CP021983.1|WP_088429363.1|1467257_1469507_+|1,4-alpha-glucan-branching-protein-GlgB
MVCQTPIDQIKRITENQHDNPFEILGSHVLEDQDHHKRWVVRAFLPNADAVWVINPEARRQHPMQSVHHPHFFECEVEADELAMNYLLKIKEGEHERVIHDPYAFKTPLLTDYDIYLFGEGNHHRIYEKMGAHPVEVDGVAGVYFSVWAPNARNVSIIGDFNQWDGRKHQMRRLNGGVWDLFIPELTAGTTYKYEIKNPAGHLYYKSDPYGFQQEVRPNTASVVNDLEYTWGDDDWLEARRHQDPQQEPISVYEVHLGSWLHASADQPPEPGEVVRVSQKPEGRFLTYRELAHTLVPYAKELGYTHIEVLPVAEHPYDGSWGYQVAGHYAPTSRFGTPQDFMYFVDQCHQQGLGVIVDWVPGHFPKDSHGLACFDGSHLYEHADPRKGEHKGWGTLVFNYSRREVSNFLIANALFWFDKYHIDGIRVDAVASMLYLDYDRKDGEWVPNRFGGNENLEVVDFLRQLNYLIFGYYPGVLSIAEESTAWPNVSRPTYIGGLGFNLKWNMGWMHDMLDYFSTDPLYRRYHQNHITFSIWYAFSENFMLALSHDEVVHGKGNLYQKMPGDEWQKLANLRALYGYMYTHPGKKTLFMGMEFGQTSEWNCWLDLDWGLLNQIPHQQLKQFIGDLNALYKSQPALYTDDFSAAGFEWIDCNDADNSVVSFIRQAKDSPDFLVTVCNFTPTPLFDYWVGVPEPGHYQELINSDAEIYGGSDTGNFGGKDTQPWPENPRWPHALSLTLPPLGVLVLKLS
>NZ_CP021983.1|WP_080814233.1|1466492_1466996_+|tetratricopeptide-repeat-protein
MTDAITLPIAPAGPGTASVAANVGETRQEGSEYFWFQRGVLLANSQQYAEALVDFEATLALFPTLIEALLYQGVCRLHLRQPAAALASCDRILTLVPHHTQALLFRGVALQQLGQYRQAYAVYDQALEGFCCPLQQHWWHHLPSLITPWQSLWNHILSSRHSVKPLS
>NZ_CP021983.1|WP_080814262.1|1465765_1466110_-|glutaredoxin-3
MTLQHRINQWLGRHPETIKAHVEIYTWQTCPYCIRAKLLLWWKGVTFTEYKIDGDGGARLRMAKRAHGRKTVPQIFVNDQHIGGCDQLYALDRQGRLDALLATAPSPEGVLETS
>NZ_CP021983.1|WP_080814232.1|1464495_1465749_+|glycosyl-transferase
MKSLILSTSDIEGGAARAAYRLHQGLQAMGSPSQLLVRAKFSGDKSVIVEKSMLTKLGPPMNTLMMRRYPQRQRKLFSSQWFPDAIASQVARLNPDVVNLHWVSNGFLRIETLAKLKKPLFWTLQDMWPFTGGCHYSEACDRYQQACGRCPQLKSNRERDLSRSIWQRKRKAWKGINLTIVTPSHWMADCVRASSLLQHRRVEVIPFCLDTSLYRPLPTALARQALNLPADKRLVLFGALSATSDHRKGFHLLVPALKRLSQQAQWQDTVELAVFGSSAPATPVDLGFKAHYLGSFQDDLSLALIYSAADVMVVPSLYESFGQTTSEALACGTPVVAFNATGPKDVVDHQLNGYLASPYDVDDLAHGIGWILADPERHQRLSLQAREKAEHAFPLRRQAQAYLTLFEQVLSQSAATA
>NZ_CP021983.1|WP_080814266.1|1483018_1483639_+|UPF0016-domain-containing-protein
MLTGFTAGLLLITLSELGDKTFFIGAILAMRHSRRWVFTGVTAALLAMTILSVLIGQVVTALPHVYVQGVAIALFLGFGGKLLYDAWSMARPGDLDHEQADALAAVEQREQGLTTWSTGAILAEAFTLTFMAEWGDRTQLATITLAAAHHPIGIVAGASLGHTITTCIAVICGKLVAGRISERLLTGLGGGLFVLFGLITALRMGT
>NZ_CP021983.1|WP_080814244.1|1483646_1485035_-|phosphodiesterase
MPTPRLLIIGLDCMEPSLVFEQWRSQLPHLSRLMAQGSYGRLESSIPAITVPAWSCMMTGRDPGELGIYGFRNRQDRNYHSMAISDGRAVKFPRLWDLLGEAGWQVAVLSVPGTSPPYPVNGSLVSCFLTPSPEVPFTHPPELGQQLRSWMPDFMMDVPNFRSDDKKQILENLYRLCDQRFTLAEKLIVQDGPDFLMLVDMGVDRIHHAFWKPMDPRHPQYEPDSPYATAIYDYYRHVDQRVGSLLEHCDQDTAVLVVSDHGAQPLMGGICINEWLQAQGYLTLKQRPDTPQSLDQVAVDWEQTQAWGAGGYYARIFLNVKGREPQGVVPMAAYEATRDQLIDQLSQLPGPAGCPLKVEAFKPQQIYQKVRGRAPDLIVYFDDLAWRSIGSVGFDSIYAVENDTGPDDANHAPQGLMIFYDPQDPKQGQVLQQAQLYDILPSLLHRYSLVAPAGLRGQQLSW
>NZ_CP021983.1|WP_088429371.1|1485073_1486255_-|aldo/keto-reductase
MQYRRFGRTNLPMPVFSCGGMRYQHSWKDSPHWQIPQKNQANLEATIRRALEVGITHIETARGYGTSEIQLGRILPRLPREKLIVQTKISPKPDPQDFRRTLEQSLQNLRLEHIDLLGIHGINTPDLLDYTVRPGGCLEVAQAFQRAGRIGHIGFSTHAPTWVILQAIETNQFDYVNLHWYYINQDNWPAIEAANRHDMGVFIISPSDKGGHLYNPPQKLVDLCAPLSPMVFNDLFCLSHPQVHTLSLGAARPSDFDEHLQVLPLLEQAAEILPPIVQRLEQAASDALGTDWLRTWQVGLPTPEDTPGRINIPTILWLHNLLVAFDMDEYAKARYNLLGNGGHWFPGQQAGDIDRLDLSKCLARSPHAQKIPKLLAETHQRLGGETVKRLSQS
>NZ_CP021983.1|WP_080814246.1|1486906_1487632_-|TIGR03985-family-CRISPR-associated-protein
MRVDSYQQQIEALWQTPDGGVIQFDNWVVRQRRTATVTVYPVCVHYARRAKYLSAYGQDPDGHIGWHNYRLDRIRSPHLRVLPWGDPAVPPELKTLRDTGQLPTPEQVQVQLAAAWGFNFYLPKALLIMRFEPEFAHGYVQDTERHPTFGPVSYGELAQLVHIEVAEATEQQEILQVLAQRPATDAYYRGWMRVGDINVTMRLRDWRPQGEVIAPLVVRQQMMSEAARELDNYGILRNPAI
>NZ_CP021983.1|WP_080814247.1|1487860_1488586_-|hypothetical-protein
MLKTLLVFLFSPNVDSYINAISYAYENMGIEAIKLIHIKGTETGITDSEASNISSKIWGRLGDLSSRFSGVYKQINEQLLKRELIPIEYSNLKRELYQVIKSQKNTKWIVDLTTAPKRPSIDVFAVCLALGIESVYTFELKPKYDPNRSDDFLYHVLNETDYSYTCLSKTDPVRNSQSSLLRKSYLLWYVGAISLVVMLISLIVFITIGPESSFIQGLNLTAAVVGLISPAFALVDQKRRV
>NZ_CP021983.1|WP_080813553.1|1488578_1488971_-|hypothetical-protein
MTKLYFAADGDDVGHHLEYLMLRNESAKIFEFSKVFHKAMLWLEYELIESCEAEIIFTGGDNILARISKTDDTLNLIEKIRFEFQKKAKSTLSIGLGKTPREAYFALKLAKTSGKNCVRQFRELEDFLDA
>NZ_CP021983.1|WP_080813551.1|1489701_1491072_-|IS4-family-transposase
MMPNRAAVLKEQYQNSIGLPFSDVLPEAEIQAVLEAQGVTYRQVLYTPIVVLWSWLSQVLDSDSSLSHAVKRVTTWMRVAGLSVPSADTGAYSKARKRWPESIFPPLVKRVATALQAQVSPAQRWCGRVVRAFDATTILMSDTEVNQRAYPQHSNQKSGCGFPLLKLQVWFCVTTGAVLEVAMAPFRVSEWRLARHLYQTLCPEDVVVADSAYGTYVDLAGVTAMGADAVFRKHHQRRCDFRRGKKLGIGDHIVRWQRPKKCPHALSPEEFEALPEALEVREVYLSIQVPGFRPSNFVVVTTLIDPKRYPRAKLAQLYQLRWQAAEVNLRHLKTTLAMEMVAAKTPTMVTKSIWVHLLAYNLLRTLMWEAGADAEVGALRLSLQGTRQQFNHFRPELLHLSPSARPQGYQALLNAVRELIIPFRPHRSEPRVVKRRPKPFPRMQEPRSVAKAKLVA
>NZ_CP021983.1|WP_088429373.1|1492044_1492227_+|hypothetical-protein
MTLAKASETALIRGHKRLEDTTIQLMQLSDYSNGVGITFSASKTGMTHKILIWILSIMSS
>NZ_CP021983.1|WP_088429375.1|1492449_1493718_+|toll/interleukin-1-receptor-domain-containing-protein
MNTAPTTSYRSPFVSTFLSHSSADSDLAAAVTKRLGRRGVLTWLDKNELLEMGSLDGVLKQAVQQQATLTLFLSEASLKSEWCRDELRWAIEAQAGTDHLLPVYLGDPLKLIKSHPLLRERFLHADGNRVNQLGYACQQEAGEPNPDAIAQKIAATAYHRSIPDPWSEVVIVLDQRGSGPRRGLPKLPANIASLQAPTLTFRPDTRSRQMRELLTGDDWDDMANTLKQSLSNALGTVRGEPRKVRVLGNAQTGLVWAVGRHFDRTTAADLYGYDRDGLAVTNQGQARHTPLLGGNPERAQPANDKAKAPEVKLPTVALGIGSQRRYGSQVQDAGPDLPLFWIESGSIEDSKQAMELVADIVASVEQLRREYGTRELVLFWTTANHVALLAAANLTSHVIPKIKYMEWDHANDRYVHLPMLGD
>NZ_CP021983.1|WP_080813546.1|1493814_1494435_+|hypothetical-protein
MPFSGFKSLGETLKEFEIVYTEANFIEGVPFAISDYFRQDLRLMLDDAVVDNSEYAICENLVYPILKEIWKQYRRNFILWSHEFLNCDAQLSGFPEYILARRSPLGKIVFDKPYFVLVEAKQDNFDAAWSQCLAEMIAAQRLNDNEQLVIFGITSNGDRWQFGKLDGTQFTLNRTFYTIQELDTLFAAVNYVFQQCEQQLNALIAV

Crispr_ID: NZ_CP021983_12

• CRISPR_ID: NZ_CP021983_12
• CRISPR_location: 1777108-1777357
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_CP021983_12

Consensus_repeat	Method
GCTTCAATGGGGCCGCTCATTTAGAGAGCGGTGCGAC	PILER-CR
GCTTCAATGGGGCCGCTCATTTAGAGAGCGGTGCGAC	CRISPRCasFinder
GCTTCAATGGGGCCGCTCATTTAGAGAGCGGTGCGAC	CRT

spacers of NZ_CP021983_12

>12.1|1777145|34|NZ_CP021983|PILER-CR,CRISPRCasFinder,CRT
CCACTATGATGTGCCGCTTACTCAGAAGGCCTGG
>12.2|1777216|35|NZ_CP021983|PILER-CR,CRISPRCasFinder,CRT
TCTTTTTCACCAATTTTCGAAGAGGCGAGGAGCAA
>12.3|1777288|33|NZ_CP021983|CRT
GCAAAGAACAAATAGATCAGATGCCGGTTATTG

CRISPR arrays and Neighbor proteins around NZ_CP021983_12

CRISPR arrays

The CRISPR arrays of NZ_CP021983_12

>merge|NZ_CP021983|12|1777108-1777357|PILER-CR,CRISPRCasFinder,CRT
GCTTCAATGGGGCCGCTCATTTAGAGAGCGGTGCGACCCACTATGATGTGCCGCTTACTCAGAAGGCCTGGGCTTCAATGGGGCCGCTCATTTAGAGAGCGGTGCGACTCTTTTTCACCAATTTTCGAAGAGGCGAGGAGCAAGCTTCAATGGGGCCGCTCATTTAGAGAGCGGTGCGACGCAAAGAACAAATAGATCAGATGCCGGTTATTGGCTTCAATGGGGCCACGCAGAGCATGGGGTGAGTTCC

>NZ_CP021983|12|4|1777108-1777287|PILER-CR
GCTTCAATGGGGCCGCTCATTTAGAGAGCGGTGCGAC	CCACTATGATGTGCCGCTTACTCAGAAGGCCTGG
GCTTCAATGGGGCCGCTCATTTAGAGAGCGGTGCGAC	TCTTTTTCACCAATTTTCGAAGAGGCGAGGAGCAA
GCTTCAATGGGGCCGCTCATTTAGAGAGCGGTGCGAC

>NZ_CP021983|12|13|1777108-1777287|CRISPRCasFinder
GCTTCAATGGGGCCGCTCATTTAGAGAGCGGTGCGAC	CCACTATGATGTGCCGCTTACTCAGAAGGCCTGG
GCTTCAATGGGGCCGCTCATTTAGAGAGCGGTGCGAC	TCTTTTTCACCAATTTTCGAAGAGGCGAGGAGCAA
GCTTCAATGGGGCCGCTCATTTAGAGAGCGGTGCGAC

>NZ_CP021983|12|4|1777108-1777357|CRT
GCTTCAATGGGGCCGCTCATTTAGAGAGCGGTGCGAC	CCACTATGATGTGCCGCTTACTCAGAAGGCCTGG
GCTTCAATGGGGCCGCTCATTTAGAGAGCGGTGCGAC	TCTTTTTCACCAATTTTCGAAGAGGCGAGGAGCAA
GCTTCAATGGGGCCGCTCATTTAGAGAGCGGTGCGAC	GCAAAGAACAAATAGATCAGATGCCGGTTATTG
GCTTCAATGGGGCCACGCAGAGCATGGGGTGAGTTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_088429476.1|1781547_1782018_-|MEKHLA-domain-containing-protein	unknown	unknown	gnl|CDD|378025
NZ_CP021983.1|WP_080806008.1|1779171_1780500_-|glutamate-5-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|234685
NZ_CP021983.1|WP_080813551.1|1788349_1789720_-|IS4-family-transposase	unknown	unknown	gnl|CDD|376573
NZ_CP021983.1|WP_088429480.1|1783995_1787394_+|NgoFVII-family-restriction-endonuclease	unknown	unknown	gnl|CDD|197275
NZ_CP021983.1|WP_080806024.1|1771867_1772545_-|peptide-methionine-(S)-S-oxide-reductase-MsrA	unknown	unknown	gnl|CDD|234604
NZ_CP021983.1|WP_080806103.1|1787990_1788281_+|nucleotidyltransferase	unknown	unknown	gnl|CDD|224583
NZ_CP021983.1|WP_080806010.1|1778354_1778729_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080814250.1|1791841_1792747_-|glycerol-acyltransferase	unknown	unknown	gnl|CDD|153249
NZ_CP021983.1|WP_088429478.1|1782103_1782625_-|metal-binding-protein	unknown	unknown	gnl|CDD|370771
NZ_CP021983.1|WP_080806025.1|1768953_1771251_+|1,4-alpha-glucan-branching-protein-GlgB	unknown	unknown	gnl|CDD|235445
NZ_CP021983.1|WP_080806027.1|1767424_1768261_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080806001.1|1787418_1787973_+|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NZ_CP021983.1|WP_088429470.1|1767058_1767346_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080806018.1|1774389_1774608_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080806020.1|1773714_1774149_+|glyoxalase	unknown	unknown	gnl|CDD|319945
NZ_CP021983.1|WP_080806104.1|1768555_1768831_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080806016.1|1774706_1775405_-|phosphoglycerate-mutase	unknown	unknown	gnl|CDD|234902
NZ_CP021983.1|WP_088429472.1|1772746_1773511_-|TIGR00297-family-protein	unknown	unknown	gnl|CDD|224749
NZ_CP021983.1|WP_080806012.1|1777424_1777622_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088429474.1|1776202_1776814_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_088429476.1|1781547_1782018_-|MEKHLA-domain-containing-protein	gnl|CDD|378025	pfam08670, MEKHLA, MEKHLA domain. The MEKHLA domain shares similarity with the PAS domain and is found in the 3' end of plant HD-ZIP III homeobox genes, and bacterial proteins.	9.00176e-74
NZ_CP021983.1|WP_080806008.1|1779171_1780500_-|glutamate-5-semialdehyde-dehydrogenase	gnl|CDD|234685	PRK00197, proA, gamma-glutamyl phosphate reductase; Provisional.	0
NZ_CP021983.1|WP_080806024.1|1771867_1772545_-|peptide-methionine-(S)-S-oxide-reductase-MsrA	gnl|CDD|234604	PRK00058, PRK00058, peptide-methionine (S)-S-oxide reductase MsrA.	1.85731e-160
NZ_CP021983.1|WP_080806001.1|1787418_1787973_+|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	3.14983e-32
NZ_CP021983.1|WP_080814250.1|1791841_1792747_-|glycerol-acyltransferase	gnl|CDD|153249	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this suubgroup are such LPLATs as 2-acylglycerol O-acyltransferase (MGAT), and similar proteins.	1.53458e-31
NZ_CP021983.1|WP_088429478.1|1782103_1782625_-|metal-binding-protein	gnl|CDD|370771	pfam09988, DUF2227, Uncharacterized metal-binding protein (DUF2227). Members of this family of hypothetical bacterial proteins possess metal binding properties; however, their exact function has not, as yet, been determined.	2.26967e-60
NZ_CP021983.1|WP_080806025.1|1768953_1771251_+|1,4-alpha-glucan-branching-protein-GlgB	gnl|CDD|235445	PRK05402, PRK05402, 1,4-alpha-glucan branching protein GlgB.	0
NZ_CP021983.1|WP_080813551.1|1788349_1789720_-|IS4-family-transposase	gnl|CDD|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	2.33661e-07
NZ_CP021983.1|WP_080806103.1|1787990_1788281_+|nucleotidyltransferase	gnl|CDD|224583	COG1669, COG1669, Predicted nucleotidyltransferases [General function prediction only].	1.89335e-19
NZ_CP021983.1|WP_080806020.1|1773714_1774149_+|glyoxalase	gnl|CDD|319945	cd08357, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) familyprotein, glyoxalase I, and type I ring-cleaving dioxygenases. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.73404e-40
NZ_CP021983.1|WP_088429480.1|1783995_1787394_+|NgoFVII-family-restriction-endonuclease	gnl|CDD|197275	cd09178, PLDc_N_Snf2_like, N-terminal putative catalytic domain of uncharacterized HKD family nucleases fused to putative helicases from the Snf2-like family. N-terminal putative catalytic domain of uncharacterized archaeal and prokaryotic HKD family nucleases fused to putative helicases from the Snf2-like family, which belong to the DNA/RNA helicase superfamily II (SF2). Although Snf2-like family enzymes do not possess helicase activity, they contain a helicase-like region, where seven helicase-related sequence motifs are found, similar to those in DEAD/DEAH box helicases, which represent the biggest family within the SF2 superfamily. In addition to the helicase-like region, members of this family also contain an N-terminal putative catalytic domain with one copy of the conserved HKD motif (H-x-K-x(4)-D, where x represents any amino acid residue), and have been classified as members of the phospholipase D (PLD, EC 3.1.4.4) superfamily.	2.71541e-33
NZ_CP021983.1|WP_088429472.1|1772746_1773511_-|TIGR00297-family-protein	gnl|CDD|224749	COG1836, COG1836, Predicted membrane protein [Function unknown].	2.64473e-65
NZ_CP021983.1|WP_080806016.1|1774706_1775405_-|phosphoglycerate-mutase	gnl|CDD|234902	PRK01112, PRK01112, 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase.	2.94262e-147
NZ_CP021983.1|WP_088429474.1|1776202_1776814_-|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	5.99119e-30

Protein sequences

>NZ_CP021983.1|WP_088429474.1|1776202_1776814_-|Uma2-family-endonuclease
MTPAIAPPLSFLKFLETLPEDGNRYELVNGERVQLMATRAHDDVADFIYDAFRDEVRRDQLNYKVSRFASVKTRRDDGLVQGRTPDVSVIDKAVWTSDPKAYAALEDPIQLAVEVSSTNWRDDYLYKLAEYEALGILEYWIVDYLAVGATRYIGSPKTPTISVYTLENGEYQLQQFRGCDRITSMTFPKLTLTAEAILQASGL
>NZ_CP021983.1|WP_080806016.1|1774706_1775405_-|phosphoglycerate-mutase
MPILILLRHGQSLWNADNLFTGWVDVPLSERGRAEATIASCKLRDYRVDVCYTSLLFRAMETAVICLTECDDICGGKTPIFKHDADDPDWHGWDRYQVDPTKELPIFPSSKLDERYYGDLQGLNKAETAAKFGQEQVQEWRRSFDVRPPGGESLEDTMNRAVPFFCDRILPHLKQGDNVLISAHGNSLRAIIMYLDRLAPEEVPGLELMTGVPIVYDIDAQGNVVHKQVLDK
>NZ_CP021983.1|WP_080806018.1|1774389_1774608_+|hypothetical-protein
MATRLCELVEQVLTTGYLDVQTERQLKALLRQEHKPEDFDAFMNLQWAVMDGLVIQESRERYRQQLQRSKRA
>NZ_CP021983.1|WP_080806020.1|1773714_1774149_+|glyoxalase
MSASVLFHLAFPVANIPQTKEFYVEGLGCLPGRESPSSLILNFYGHQLVAHVSQEPLTPQRGIYPRHFGLVFPQAADWDALLQRAQDKHLTFHQPARRRFPDSPLEHRTFFLEDPFYNLLEFKYYCDASAIFGQTALAQIGDSE
>NZ_CP021983.1|WP_088429472.1|1772746_1773511_-|TIGR00297-family-protein
MDVSPALQPWLWGVAINTALLAIAWVAPKKLLTVAGYFHAWILGVLIWGCLGWAGYTVVMVYFLVGSAVTRIGAARKQAAGIAEGRSGRRGPENVWGSAAAGSLCALGILALQAQGNMAGGALLALGFVASFSTKLSDTTASEVGKAYGRRTFLVTTLKPVPPGSEGAVSLEGTLAGVVASVAIAFVGWAVGLIPASGIILCAIAALIATTCESLIGATLQETITWLTNELVNVINTLIGAIIAIALQWLLWQI
>NZ_CP021983.1|WP_080806024.1|1771867_1772545_-|peptide-methionine-(S)-S-oxide-reductase-MsrA
MVLFGFGKKQSLPSSEEALSGRAEKMPVPERHYVNGNSLTPPFPAGMETAMFGLGCFWGAERKFWQLEGVYTTAVGYAAGHTPNPTYHEVCSGMTGHAEVVLVVFDPKVISYEQLLKTFWESHNPTQGMRQGNDTGTQYRSGIYVYSEAQRQLAEASRDAYQQALTKAGYGNITTEILDAPEFYYAEAYHQQYLAKNPGGYCGLGGTNVTCPVGLSDGVMGRADM
>NZ_CP021983.1|WP_080806025.1|1768953_1771251_+|1,4-alpha-glucan-branching-protein-GlgB
MAVTVAPEQIDRIVWNQHHDPFEVLGPHMVQLDGKTVWAVRAYLPNAEAAWVVLPETRKEFAMEASHHPHFFECIIAAEEVVNYQLRYQEGGHERVVYDPYAFKTRRITDFDIHLFAEGNHHRIYEKLGAHPTTMEGIAGVYFAVWAPNARNVSVLGNFNHWDGRKHQMRRSGNGIWELFIPDIAAGEHYKYEIKNPSGHMYEKADPYGFQQEVRPKTASVVANLDGYSWHDQDWMEQRRHTEPLTQPISVYEVHLGSWLHGSSAQPATNPDGTPVSPVAVAELKPGARFLTYRELAERLIPYVKEMGFTHIELLPVAEHPFDGSWGYQVTGYYAVTSRYGTPQDFMYFVDQCHQNGIGVIVDWVPGHFPKDGHGLAFFDGTHLYEHADPRRGEHKEWGTLVFNYGRNEVRNFLVANAVFWFDKYHIDGMRVDAVASMLYLDYCRKPGEWVTNQYGGRENIEAADFLRQTNHVLFSYFPGILSIAEESTSWPMVSWPTYVGGLGFNLKWNMGWMHDMLDYFHMDPWFRQFHQNNVTFSIWYAYSENFMLALSHDEVVHGKSNMLGKMPGDDWQKFANLRCLYSYMFMHPGKKTLFMSMEFGQWSEWNVWGDLEWHLLQYTPHQTLRRCISQLNALYRSEAALYSQDFSEEGFEWIDCSDGRHSVVSFMRRAKDSQEFIVVVCNFTPQPHSHYRIGVPEQGYYREIFNSDARDFNGSNMGNLGGKWSEDWSYHGRSFSLDLTLPPLAVIALKLDRQRTWEAKAENG
>NZ_CP021983.1|WP_080806104.1|1768555_1768831_+|hypothetical-protein
MVIGLFSVGWSQPVLGLPPADETPEEVLRTEIIVEARSPLDGEPLSPSEYAELQAQLQDPNRERTLSSEVRYVIFLLQLRRVIKPVVPFLP
>NZ_CP021983.1|WP_080806027.1|1767424_1768261_+|hypothetical-protein
MFQSIAWPRVPHRAGTWLRQVRAVLPGAINERLIQFCGIQRSGNHAVINWIIAQQSLKTCFINGVNPRHNPWFNNWGIAYHNYDYWPRERDRTGALVSKQLLLCSYENQPLNHVFDPSFRLQRYVGGSRRRDSVLLLRDPYNTFASWFKAGWPLSEDTIYLWKQYAREYLGLSQQTPPGTVMIAFNQWFTQADYRQRLADALDLPFTDHGLDRITHHGGGSSFEQQVLQGKASHMKVLERFKGFLDHPDFIQIFRDPDLIDLSEQIFGPIPGTEMLTR
>NZ_CP021983.1|WP_088429470.1|1767058_1767346_+|hypothetical-protein
MICLTLGLRARSSPRVLSLTKALAQHHPLIIGDGPLWQLWLNGVTMYSSRLAHQSIRSLRRMGAEPSLRLLVDILIRQLIMVTGVALALTALLDL
>NZ_CP021983.1|WP_080806012.1|1777424_1777622_+|hypothetical-protein
MSSAERQAPSSEASDQAYDGLLDKEKQLNALSERMLLAVAVQYGKDSYEYEMAGGTRTSERKRLG
>NZ_CP021983.1|WP_080806010.1|1778354_1778729_-|hypothetical-protein
MFLPSALCLLPSAFCLLPSALCFLPFPALLPCPLTLYLLSAYSPAHPPFDREPKHSLTQHSTLKTHHFPPPSLSPVGPFLATHDLPRFSKTTHATHSPSPHHPITPSPHHPITPFPLSAFCLPI
>NZ_CP021983.1|WP_080806008.1|1779171_1780500_-|glutamate-5-semialdehyde-dehydrogenase
MTAFQSPVSLQQPAFSLTKVAQQTRQAARSLASLSTPVKNQAIEAMAQALAAAEAEILAANATDCESALASHLAQPLYDRLKLDAVKLRAAIAGVRNVAQLPDPVGQVQIHRQLDQGLVLKRITCPLGVLGVIFESRPDAVMQIASLAVKSGNGVILKGGKEAVRSCRALVAAIQQGLEQVGLDSAAVQLLTTREETRALLALDEYVDLIIPRGSNAFVRYVQDNTRIPVLGHAEGICHLYVDAAADVEKGVAIALDAKVGYPSACNAIETLLVHRAIAPQFLPTAAAALQQEQVDLRGDAATQTFLPDIIPASESDWATEYSARILAIKVVDSLEAAIDHINTYGSRHTEAIITEDEAAAASFMDRVNAAGVYHNCSTRFADGCRYGFGAEVGISTQTMPPRGPVGLEGLVTYKYQLVGDGHIVATYSGTQAKPFQHRDLL
>NZ_CP021983.1|WP_088429476.1|1781547_1782018_-|MEKHLA-domain-containing-protein
MSQPLWQRPDIIDWSQRLLASYRHWLGQDLLPLAAAAPEAARQLFWAPRVVVSHGTQADPVLNYGNQAALDLWQLNWDRFTQTPSRHTAEPMHRQERTNMLAQLEAQGYVDNYRGVRISSQGRRFYIERAIIWNVVDDTGKRVGQAATFKEWQFLS
>NZ_CP021983.1|WP_088429478.1|1782103_1782625_-|metal-binding-protein
MPSGRTHDRITLWSLPLVLLVASRITLDPWLTGIVGGGYLFGGFMFGPDLDIHSVQYKRWGWFRWIWLPYRGSLRHRSRLSHGPIIGTTLRVLYLSLWLGLLGLIIIDVLNSLGRAQVTWADIGQGMTLGLRQFAPQWLALVCGIELGALSHSVSDWLVSSLRRQRRGQRPRR
>NZ_CP021983.1|WP_088429480.1|1783995_1787394_+|NgoFVII-family-restriction-endonuclease
MPRIFDNIEQHFHPALCSALGSAYRADFCVGYFNLRGWDEVDSQINQFAGGEGACCRLLIGMNKLPQEELYESRSLLSSKGGIDNRKVIQLKKRIAQEFRQQLAIGIPSDREEAALRKLSAQIRAKKLVVKLFLKHSLHAKLYLVHRQDAHSPIVGFLGSSNLTFSGLSYQGELNVDVLDHDACEKLQRWFDDRWNEYWCFDISEDLADLIDSSWAREQQPPPYHIYLKIAYHLSQEARAGLSEYRIPRDIDIQLFEFQKAAVQIAAHHVNRRGGVLIGDVVGLGKTLVGATLARILQDDFFLETLIICPKNLVSMWQDYVDSYRLLAKMLSISRVQNELPELRRYRVVLIDESHNLRNREGKRYRAIQEYVAMNECRCILLSATPYNKTYLDLSAQLQLFVSEDKDLGIRPEGLLDQIGGELEFIRKHQAAVRSLRAFELSEHADDWHDLMKLYMVRRTRSFIQNNYAEVEEQLPLEKEWQNRPPRKYLEFPDGRRAYFPERQPKTLKFQAEDESSPYAVLYSEAVVEAINGFNLPRYGLGNYAISTRNRKLTADEERQLKGLSRAGKRLMGFSRTNLYKRLESGGPAFIQSLDRHILRNYIFLHAIEQGLDLPIGSQEASLLDTRNNDEDTDALVASLFDVEAEDEDMATEAALDLADADYRQRAAEVYEQYATRYKRRFKWIKPALFKVALKKSLLADAQILTTILKNCGTWQATEDTKLTALIELLTLKHPDEKVLIFTQFADTARYLTDELKRAGIEQIEGVTGDSDNPAAVAWRFSPRSNHKPIPAAEELRVLVATDVLSEGLNLQDCAIIVNYDLPWAIIRLIQRAGRVDRIGQTADQILCYSFLPVEGVERIIRLRSRLRQRLQENAEVVGTDEAFFEDDMDEQTILDLYHEKSGILDGEADSEVDLTSEAYQIWKNAIDADPTLKPTIENLPPVIYSTRAHAPTSGQPEGVLVYLKTPEGNDALALIDREGKSITQSQLAILRLAQCESETPAIPKDPDHHKLVSEGVKHILKEEKSSGGQLGRPSGARFRTYERLKRHAQAVKGTLFESQDLLNAIDLIYRHPLRQTATDQLNRQLKSGIDDHQLADLVVALYQDERLCLVHESESDCEPQIICSMGLFQAR
>NZ_CP021983.1|WP_080806001.1|1787418_1787973_+|Uma2-family-endonuclease
MTITTAKWSLDEYHQMIAANILAKRRVELLNGEIVEMAPEGPEHAQTSTDAADYLRGLLGARALIREAKPITLPNSDSEPEPDIAIVHPRRELYRTRHPYPEDIFWLIEYANTSWVKDSEVKRPTYAQAGIPEYWIVNLKRLTVTVLWQPEQGDYPQATTLTQGTLTPQAFPEVEVSVQRLIEG
>NZ_CP021983.1|WP_080806103.1|1787990_1788281_+|nucleotidyltransferase
MQRETVLIKVRSARTTLEAMGVRSLHLFGSVARNQATQSSDVDFVVEFSHPVGFFQLLQVQHYLEDLLERPVDVGTLAALKAHLRQPVLEDMICVF
>NZ_CP021983.1|WP_080813551.1|1788349_1789720_-|IS4-family-transposase
MMPNRAAVLKEQYQNSIGLPFSDVLPEAEIQAVLEAQGVTYRQVLYTPIVVLWSWLSQVLDSDSSLSHAVKRVTTWMRVAGLSVPSADTGAYSKARKRWPESIFPPLVKRVATALQAQVSPAQRWCGRVVRAFDATTILMSDTEVNQRAYPQHSNQKSGCGFPLLKLQVWFCVTTGAVLEVAMAPFRVSEWRLARHLYQTLCPEDVVVADSAYGTYVDLAGVTAMGADAVFRKHHQRRCDFRRGKKLGIGDHIVRWQRPKKCPHALSPEEFEALPEALEVREVYLSIQVPGFRPSNFVVVTTLIDPKRYPRAKLAQLYQLRWQAAEVNLRHLKTTLAMEMVAAKTPTMVTKSIWVHLLAYNLLRTLMWEAGADAEVGALRLSLQGTRQQFNHFRPELLHLSPSARPQGYQALLNAVRELIIPFRPHRSEPRVVKRRPKPFPRMQEPRSVAKAKLVA
>NZ_CP021983.1|WP_080814250.1|1791841_1792747_-|glycerol-acyltransferase
MALDRDFLKAAATVVEQYVRARLAPADTLTGWSLDDRDPDTISALLPFYGWLYRHYFRVQTDGWQHIPETGNVLLIGSHNGGLAAPDTVMMAYDWLRRFGPDRPVYALMEPSIWRLLPGVARLATQVGTLQANSQLAVAALRRGASLLIYPGGLRDVFRPHSQRDRICFYHNTGFIKLALLEEVPIVPLISYGAHDTLIVLADLYPYLAQLHRWGLPWLFGLDPEVWPLYLGLPWGLSPGPLPNLPLPVPLHTRVCPPIIFERCGLAAAHDEAYIEACYHRVCETMQRQLDQLFAEHQPEG

Crispr_ID: NZ_CP021983_13

• CRISPR_ID: NZ_CP021983_13
• CRISPR_location: 2138193-2138305
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP021983_13

Consensus_repeat	Method
CGCAGCGCTCTACCAACTGAGCTAATTCCCC	CRISPRCasFinder

spacers of NZ_CP021983_13

>13.1|2138224|51|NZ_CP021983|CRISPRCasFinder
GTGTTGTCCGCACCGCATCGGTGCGATTGGCCTGCGGCCACCCTGCGGGAA

CRISPR arrays and Neighbor proteins around NZ_CP021983_13

CRISPR arrays

The CRISPR arrays of NZ_CP021983_13

>merge|NZ_CP021983|13|2138193-2138305|CRISPRCasFinder
CGCAGCGCTCTACCAACTGAGCTAATTCCCCGTGTTGTCCGCACCGCATCGGTGCGATTGGCCTGCGGCCACCCTGCGGGAACGCAGCGCTCTACCAACTGAGCTAATTCCCC

>NZ_CP021983|13|14|2138193-2138305|CRISPRCasFinder
CGCAGCGCTCTACCAACTGAGCTAATTCCCC	GTGTTGTCCGCACCGCATCGGTGCGATTGGCCTGCGGCCACCCTGCGGGAA
CGCAGCGCTCTACCAACTGAGCTAATTCCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_080813837.1|2138319_2139084_-|HAD-family-phosphatase	unknown	unknown	gnl|CDD|223710
NZ_CP021983.1|WP_080813822.1|2149442_2149814_+|LuxR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197715
NZ_CP021983.1|WP_080813826.1|2148700_2148961_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|198034
NZ_CP021983.1|WP_088431613.1|2145191_2145425_-|hypothetical-protein	unknown	unknown	gnl|CDD|367139
NZ_CP021983.1|WP_080813828.1|2147993_2148197_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088429658.1|2140051_2140447_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080813846.1|2118862_2119285_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080813849.1|2117167_2118352_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173847
NZ_CP021983.1|WP_088429660.1|2143188_2143806_+|dephospho-CoA-kinase	unknown	unknown	gnl|CDD|184807
NZ_CP021983.1|WP_088429656.1|2136957_2137560_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NZ_CP021983.1|WP_088429654.1|2133900_2136021_+|acylase	unknown	unknown	gnl|CDD|376618
NZ_CP021983.1|WP_088429650.1|2120441_2125955_-|FkbM-family-methyltransferase	unknown	unknown	gnl|CDD|225858
NZ_CP021983.1|WP_088429661.1|2143808_2145173_-|sorbosone-dehydrogenase	unknown	unknown	gnl|CDD|225044
NZ_CP021983.1|WP_080813844.1|2119299_2119545_-|acyl-carrier-protein	unknown	unknown	gnl|CDD|376348
NZ_CP021983.1|WP_080813840.1|2136307_2136922_+|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NZ_CP021983.1|WP_080813832.1|2141447_2141873_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080813842.1|2119565_2120420_-|3-hydroxybutyryl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|180269
NZ_CP021983.1|WP_080813848.1|2118355_2118838_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088429663.1|2148947_2149379_+|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|350250
NZ_CP021983.1|WP_088429652.1|2125955_2131271_-|non-ribosomal-peptide-synthetase	unknown	unknown	gnl|CDD|235564

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_080813837.1|2138319_2139084_-|HAD-family-phosphatase	gnl|CDD|223710	COG0637, COG0637, Predicted phosphatase/phosphohexomutase [General function prediction only].	2.46676e-35
NZ_CP021983.1|WP_080813826.1|2148700_2148961_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl|CDD|198034	smart00966, SpoVT_AbrB, SpoVT / AbrB like domain. This domain is found in AbrB from Bacillus subtilis. The product of the abrB gene is an ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. AbrB is thought to interact directly with the transcription initiation regions of genes under its control. AbrB contains a helix-turn-helix structure, but this domain ends before the helix-turn-helix begins. The product of the B. subtilis gene spoVT is another member of this family and is also a transcriptional regulator. DNA-binding activity in this AbrB homologue requires hexamerisation. Another family member has been isolated from the Sulfolobus solfataricus and has been identified as a homologue of bacterial repressor-like proteins. The Escherichia coli family member SohA or Prl1F appears to be bifunctional and is able to regulate its own expression as well as relieve the export block imposed by high-level synthesis of beta-galactosidase hybrid proteins.	8.02479e-11
NZ_CP021983.1|WP_088429652.1|2125955_2131271_-|non-ribosomal-peptide-synthetase	gnl|CDD|235564	PRK05691, PRK05691, peptide synthase; Validated.	0
NZ_CP021983.1|WP_080813849.1|2117167_2118352_-|acyl-CoA-dehydrogenase	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	1.51762e-118
NZ_CP021983.1|WP_088429660.1|2143188_2143806_+|dephospho-CoA-kinase	gnl|CDD|184807	PRK14730, coaE, dephospho-CoA kinase; Provisional.	4.89201e-103
NZ_CP021983.1|WP_088429656.1|2136957_2137560_-|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	4.59329e-29
NZ_CP021983.1|WP_088429654.1|2133900_2136021_+|acylase	gnl|CDD|376618	pfam01804, Penicil_amidase, Penicillin amidase. Penicillin amidase or penicillin acylase EC:3.5.1.11 catalyzes the hydrolysis of benzylpenicillin to phenylacetic acid and 6-aminopenicillanic acid (6-APA) a key intermediate in the the synthesis of penicillins. Also in the family is cephalosporin acylase and aculeacin A acylase which are involved in the synthesis of related peptide antibiotics.	2.89236e-141
NZ_CP021983.1|WP_088431613.1|2145191_2145425_-|hypothetical-protein	gnl|CDD|367139	pfam02672, CP12, CP12 domain. The function of this domain is unknown, it does contain three conserved cysteines and a histidine, that suggests this may be a zinc binding domain (Bateman A pers. observation). This domain is found associated with CBS domains in some proteins pfam00571.	7.98227e-23
NZ_CP021983.1|WP_088429661.1|2143808_2145173_-|sorbosone-dehydrogenase	gnl|CDD|225044	COG2133, COG2133, Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism].	5.67358e-79
NZ_CP021983.1|WP_080813844.1|2119299_2119545_-|acyl-carrier-protein	gnl|CDD|376348	pfam00550, PP-binding, Phosphopantetheine attachment site. A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This domain forms a four helix bundle. This family includes members not included in Prosite. The inclusion of these members is supported by sequence analysis and functional evidence. The related domain of the anguibactin system regulator AngR has the attachment serine replaced by an alanine.	0.00393434
NZ_CP021983.1|WP_080813840.1|2136307_2136922_+|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	1.86942e-24
NZ_CP021983.1|WP_080813842.1|2119565_2120420_-|3-hydroxybutyryl-CoA-dehydrogenase	gnl|CDD|180269	PRK05808, PRK05808, 3-hydroxybutyryl-CoA dehydrogenase; Validated.	3.56164e-118
NZ_CP021983.1|WP_088429650.1|2120441_2125955_-|FkbM-family-methyltransferase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
NZ_CP021983.1|WP_088429663.1|2148947_2149379_+|PIN-domain-containing-protein	gnl|CDD|350250	cd18683, PIN_VapC-like, Uncharacterized subfamily of the VapC (virulence-associated protein C)-like family of the PIN domain superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.164e-48
NZ_CP021983.1|WP_080813822.1|2149442_2149814_+|LuxR-family-transcriptional-regulator	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	4.36379e-10

Protein sequences

>NZ_CP021983.1|WP_088429656.1|2136957_2137560_-|Uma2-family-endonuclease
MMIPAATRDLTFEAFIDVEDGNELNEYELVDGRLVLMPEPDDWHEEILEFLSFMFELQYRRMTLRYSVRQRNALMIDDVRGRRPDIAVIDRPATRREDRQPGIRSVPRMIVEIASGNWSTDLVEKQEEYEALQVPEYWIVDYRGQIPAKYCQRGKGKKVIVLTLEDGVYQKAEYVEGEAVPCLTFPELGLTVEQILTAEE
>NZ_CP021983.1|WP_080813840.1|2136307_2136922_+|Uma2-family-endonuclease
MTIAINPPTLTIDEFLAGYGDDNRYELIDGEVFDLEPTGPHEEVAAFITSKICVQIDLQGLPWFVLQRGLLRPSGMGNTAFRPDVAVVDRNELAKEPCWMEQSMLTLGSSIKFVAEVVSSNWQNDYARKTEDYAALGIPEYWIADYAGLGRTRYIGKPKQPTLSMGILVHGEYEVHQLRGSQNVVSPTFPSLNLTAEQVLKTGR
>NZ_CP021983.1|WP_088429654.1|2133900_2136021_+|acylase
MLSIPCLPNPMRRLIWVLLGGALALLIGVSWPLAGTTATEILWDTYGVPHIYADDTEELFRAFGWAQAQSHGDLILRLYGQARGRAAEYWGEDYLDSDRWVHTMGIPSRAQAWYEAQTPQFQTYLDAFAAGVNAYAQTHEAAIADEVEAVLPISGVDLLAHGQRVLNFTFVVNPQQVAALATDDSAAAMALPTPGSNGWAIAPQRSASGEAMLLANPHLPWSEAFRWYEAHLIAPDLNVYGASLVGIPVLNIAFNDQLGWTHTVNLHDGWDAYQLRLTEDGYWFDGQMRPFEVSTQALQVKQADGTLQPKTLTIRRSLHGPVVQEQGDTAIALRVVGLEHPGALEQWWQMGRAHTLAEFEAALQRLQIPMFTVLYADRQGHILHLFNGHVPVRSGGDVEDWSGLLPGDTSDTLWSEIHAYSELPRLLDPPTGWLQNANDPPWTTTLPPAIDPDDYPTYIAPLPSMDSRAQRSARMLAEDQQISFEEMVKYKHSPRMELADRLLDDLIPAARQQGRCTSTSGCRCPGCLGSGAAADSRAAVLFATWARQVDLERLFATPWDENAPLSTPAGLADPAGAVAALEAAAAQVQTAYGALDIAWGDVFRLRSGPVDLPASGGPGHLGIFRNLWFAPEEDGTFTAVGGDSYVAAVEFSDPVRAMAVMTYGNATQASAPRQQEQLDLAAQQQLRPVWLSRAAIEANLVVRESF
>NZ_CP021983.1|WP_088429652.1|2125955_2131271_-|non-ribosomal-peptide-synthetase
MSFSTLVDLLRRRALHQPGQKAFTFLKDGEIEAGSLTYRELDHQSRTIAARLQAMGLEGERALLLYPPGLEYLAAFFGCLYAGVIAVPAYPPRNQRNTPRILAVVKDAEAAIALTTTVIQARLQSLLRKHEDLADLQWLTTDDLAAGAAGEWQPPTLGSDSLAFLQYTSGSTGMPKGVMLSHGNLLHNAAVTYELMGHSPESVFVSWLPVYHDMGLIGGILQPLYGDFPCILMPPASFLQRPYRWLQTISHYRGTTSGAPNFAYELCVEKVTPEQRQSLDLSSWTVAFNGAEPVRSQTLERFAAEFATCGFRSQAFYPCYGMAEATLMVSGGRQQEAPVVKLLQKVALEHNRVVEANGHSVDQAQSLVGCGQTMPQQRIVIAHPETQIRCAGDEIGEIWVSGPSVGQGYWQRPAESEQTFAAYLADTGVGPFLRTGDLGFLHQGELFITGRTKDLIIIRGRNLYPQDIELTTERSHPALRSGGGAAFMVEEQREEKLVVVQELEFRQKPDPEEVTAAIREAIAQEHEVQAYAVVLIKPGTIPKTSSGKIQRRATRAGFLAGHLEVISSSLLETTIPGEVPATLNRKTLLALPPIEAQLMLVSYLQALVAEVLQITPSQINSQQPISALGLDSLKAFELKNRLEVDLQVSVSISDLFDHLNLTQLAIKILAQLELPEHLPSVPLVPVKAQRQHHPLSYPQKRLWFLDQLAPANPAYNIAFALQFQGPLSADILERSLNEVIRRHEPLRTTFKLVEGQPAQVITPSCWLPLKVVDCQNLSSEARESEVQRCATQASQQPFQLSQGPLMRAQLFHLAPQQHVLLLTLHHIIADEWSVEVLIRELLGNYKGFLSHGEIPALPAVSVQYKDFTHWQRQWLRGERMEGQLAYWIQHLEGAPAVLALPTDHPRPAVQTYQGARQSLALPHPLTEKLKALSEQENVTLFMVLLAAFKTLLYRYTGQDDILVGSPIANRSRSELKGLIGFFVNTLVLRTDLSGNPRFQELLGRVRQVALGAYAHQDVPFNQLVEALQPERDVSHTPLFQVSFTLRQAPQLDTVPGLTVRPFEVDSKTAQFDLSLVVETTEQGLTTLFEYNTDLFEAATITRMLGHWQQLLEGIVASPQTRLSDLPLLTEAERCQILKQWNDTEVDYPRDLCIHQLFEAQVERTPDAVAVVFEQQQLTYRELNQRANQLAHYLQQLGVKPEGLVGICVERSVEMVIGLLGILKAGGAYVPLDPAYPQERLAFILADAKVSVLLTQRELLEALPTEGAAVVGLDTNWEKIAQENLNNPVNQTDSKSLAYAIYTSGSTGKPKGTLIPHRGLINYLTWCVQAYEVEGGKGTIVHSSLAFDLTITGLFSPLLVGRQVTLIPEDQSVESLTNVLRKESNLSLVKLTPAQLLLLTQQLLPKEAAGRTNAFIIGGENLLTENISFWQSFAPATMLVNEYGPTETVVGCCVYRVPHGETQSSSVPIGQPIANTQLYVLDQYHQPVPIGVPGELYIGGAGLGRGYLNQPELTAEKFVPNPFSDKPGTRLYKTGDLARYRSDGNLEFLGRIDHQVKVRGYRIELGEIEGLLRQHPDIREAVVVKREDVPGDQRLVAYVVSNIGVETTTNSFRNFLKEKLPEYMVPSVFIKLKALPLTTNGKIDRQALPVPDSTRPELEAAYVAPHSEIEQAIAKVWQEVLHLEKVGINDNFFDLGGHSLLMAQVNHKLQELFNQDLSVVELFQNPTINSLAQYLSRESKQQPSFQSMRDRAQKQIEAINRQKQLLMKQGKR
>NZ_CP021983.1|WP_088429650.1|2120441_2125955_-|FkbM-family-methyltransferase
MGNIETYESVEGIAVIGMAGRFPGAKSIEEFWQNLCDGVESISFFTDEELIASGIGASVLNDPHYVKAGAVLDDIEFFDASFFDINPREAEVTDPQHRIFLECAWEALENAGYDTTRCRNRIGVYAGTGINNYLPFDISRDPMGSAQCYQTLIGNDKDFLTTRISYKLNLKGPSVTVQTACSTSLVSTTLACQSLLNYQCDVALVGGISIRVPQKIGHLYQEEGVLSADGHCRAFDAKAQGTVLGNGVGTVVLKRLEDAIADGDCIHAVIKGSAINNDGSGKVGYTAPSVEGQTEVIAEALALAEIESETVSYIETHGTGTSLGDPIEIAALTKVFRGSTDKKGFCAIGSVKTNVGHLDTAAGVTSLIKTVLALKHKQIPPSLNFKEPNPEIDFANSPFYVNTQLSEWKVNETPRRAGVSSFGIGGTNAHLILEEAPSVETSSSFRPWQLLLLSAKTSSALETATTNLGDHLQQHSELNLADVAYTLQVGRRQFDHRRAVVCQDLQDAIAALQNPKRVLTSSIQDTGTRSVAFMFTGLGPQYVNMGRELYQCQPTFREHVEHCCKILRPLLGLDLITVLYPDQDESSDDTGADLAQSGIDLRQMLGRSEEPVNAASQQLNQTWLTQPALFVIEYALAQLWQAWGVRPRAMIGYSIGEYVAACLAGVLSLEDALMLVARRAQLIQSLPSGAMLAIPLSEQEVQPLLGENLSLSAINGSSLCVVAGATDAIDELENQLTQQGLACRRLATSHAFHSHMMASMVDSFSRLVKTIRFKPPQIPYISNVTGTWITAAEATNPDYWTQHLCQPVRFADGVSQLWQKYTPALLEVGPGQTLSSLALQCLENQQVTDKVVLPSLRYTYDRQSDVAFLLNTLGQLWLAGILIDWSGFYINERRHRLPLPTYPFERQRYWIEPQKPGNPVNSGASNSQQKLDITEWFHIPSWKRAAPPVPFESGKWGNRKQPWLVLVDRCGVGSQLVKQLEKECQDIIIVGIGEEFRKLNQQEYTINPGKRDDYDTLLCELHFSNKIPKSIVHLWTITANEQAEPGLESWEQIQSLSFYSLLFLAQALGEQGIDDPLHIDIISNNLQELTDTDDICPEKATLLGPCRVIPQEYSNITCRSIDITLPQSGTRQWQQLIDQLFSELAAPTADKVIAYRGNRRWVQCFEPLPVAGKTLRTAKLRQGGVYLITGGLGGLGLAIAQHLAKTVQAKLVIIERSGLPPKTEWEQWLSNHEEDNPVSIKIKKVQAMEEFGAEVLVIKADVTHLEQMQGMVDRVRDRFGEIHGIIQTTPPIGASIIQLKTTESAASILNFKVKGAMVLDAVLKDTQLDFLVLFSSINAITGGLGQVDYSAGNAFLDAFAHYNFYRRNIHTVSINWDPGPGHNLQAAVSPEIQAGLRQMRERYGIEFKKGIAALWHILSSQQPQVVVSTRNLQTLFEENEVLAAASLLENLEKRHPQSTQLRPNLKTAYVAPRNETECKIAELYQELLGVDRIGIHDNFFDVGGNSLIGIQLLSRLRQEFQVELSLRFIFEAPSVAELALIIEEILIREIEELTENEAEELVSVLPQSSEQTPRVVSQRRYKLPNHLEIAYQTKTEADYFYQDIFENKVYLKHGIALNEGDCIFDVGANIGLFTLFAYQHCKNPIIYAFEPAPPLFEILSFNTALHEVNVKLFNVGLSNETKTATFTFYPQSSGMSSFYGDRGEEQEVLKAIMLNQLQTGMAGMEQVMQYSDELLEERFKSQSFTCQLKTLSDVISENNIENIDLLKIDVQKSELDVLQGIKDKDWKKIKQIVLEIHDTEGRLVQITNLLKTQKYNVVAEQEDLYENSNIYNVYAAR
>NZ_CP021983.1|WP_080813842.1|2119565_2120420_-|3-hydroxybutyryl-CoA-dehydrogenase
MKIQTVGVVGAGVMGVGIAQNLAQTGHQVILIDVSEEILEKANQEIKNNIRFQGFFNKKEKPENPDVVLNRIQFSTNYKLLDGVEFVIENVTEKWSIKKEVYPQLEAICPESVVFAANTSAIPITRIASVTKRASKVLGMHFMNPVPLKPTVEMIRGYHTSEETIETAKNLLSQMGKEGIVVNDSPGFVSNRVLMLTINEAIFLLHDQVASAEEVDRIFKTCFGHKMGPLETADLIGLDTILFSIEVLYESFNDSKYRPCPLLKRMVDAGLYGRKSGKGFYAYS
>NZ_CP021983.1|WP_080813844.1|2119299_2119545_-|acyl-carrier-protein
MQDFKAKLKTFLSQFFGNHDLQDDEDIFAVGFVNSMFAMQLVLFIEQEFQVTVENEDLELDNFRTISAMASLLERKKSILT
>NZ_CP021983.1|WP_080813846.1|2118862_2119285_-|hypothetical-protein
MNQFINEKMQANNHLLEATSSQTQDFYFRFLADSQHIDTQTNIYTYLRSMYGAWKHRKYFDKIENYCIFIGCGRTGHSLVGACLDTHPDMVISDELGAVKYINKHSYSKGQIYYLILKGAQVHAQAGKTVAGYSYAVPNQ
>NZ_CP021983.1|WP_080813848.1|2118355_2118838_-|hypothetical-protein
MIGDKEAAPTTAILKSYPGLLDILYKKMGTNIHFIHVIRNPYDVIDTFTKREEVDIEIAIELYSLVCKAVAELKTRIDLDKILEITNESFIENPKYCLKQLCNFLSMPASEDYLKDCASIVYNKPNKSRFNVQLNSELIDLVKKKIIDRYLFLNHYSYQG
>NZ_CP021983.1|WP_080813849.1|2117167_2118352_-|acyl-CoA-dehydrogenase
MKLELTTQQKENRAAFRVFVDEAIVPYANQWDRQERTPAELIKKFAQQGYLGALLPKDSGGSGMDMITYGLLSEEIGRGCSSLRSLLTVHSMVSLALLKWSSQSQKAYWLPKLASGEVIAAFALSEPNVGSDAKSVETTATLSGNAYLLNGQKKWITYGQIADIFLVFAQCDGKPSAFLVEKNSPGLSIEPISGMLGVRASMLAELHFNDCQILQENLVCRQGFGFSHVASTALDCGRYSVAWGCVGIAQACLEACIRYTSERKQFGVYLREHQLIRQLVTEMLTNVKAARLLCYQAGYLKEIGDPGSIAETSIAKYFASKIATQAANDAVQIHGANGCTNEYAVARCLRDAKIMEIIEGSTQIQQITIADYGYQEYTSPSPSTVNFQDLLART
>NZ_CP021983.1|WP_080813837.1|2138319_2139084_-|HAD-family-phosphatase
MTSANSHSHASLKALLLDFNGIIINDESLHCQLLEQLLLEENLRPNREDVAAACLGRSDRACLTNLLGSRGRVVSDDYLDTLLAKKSQRYIEAMSQQDLPLYPGLDDLVFQGRAAQLKLAVVTGTMQTEVAWVLRQAGIYDHLSALVCGDDLPATGSKPAPDGYLLAIERLNQAHPGLNLTPAHCLAIEDSFAGIEAAKRAQVPVAGVAHTYPYQMIHRRADWVVDNLSELDLDWLRDYYANPRPTPSSVSSVW
>NZ_CP021983.1|WP_088429658.1|2140051_2140447_+|hypothetical-protein
MTLLTPTHIQALLQEPIPDRQAYGRLMEIYCVVKAGGVRVQIEAASGHLARQQWRLEKTISELSCHHAHHPQIPILRQEVAELRRSVAWRIDFLRTIHPQEEAAVQQHLAAIEAYVAAQGEQLRGACPNNH
>NZ_CP021983.1|WP_080813832.1|2141447_2141873_+|hypothetical-protein
MVAGSGVGVGPGVAAEGVAELGTDDADGLPAAAARGASITARLRRPGDCAGGVRPGSGWSAMAEPLRGVAGLLSGAVTLGLISGGSAEVAVSTKGSSKLAVSKSGGVNDQPLSVDWLPEHAVRATKLLQEARVQMRMRIPL
>NZ_CP021983.1|WP_088429660.1|2143188_2143806_+|dephospho-CoA-kinase
MAAPSPRIIGLTGGIATGKSTVSHYLEQHHGIPVLDADAYARQAVVPGSPIFQAIVQRYGTAMVQPDGELDRRRLGDVVFYNTDEKRWLEQQIHPFVRQCFAQAMVRLQDCPVVVHSIPLLFEANLVDQVTESWVVICSEAQQCQRLMARNQLSRTDAIARIQSQMPLLDKAARADVVLDNSTTVAALYGQVDQALNEHSSITPG
>NZ_CP021983.1|WP_088429661.1|2143808_2145173_-|sorbosone-dehydrogenase
MPFCGLKALPLLLVLGLFACTEPSSVAPSPAPADSDSATPSGAEKDAAIASGAEPANPIATEPLVPSPIRITLADLPQPFASQSARKPPQVIDIPSNPRLQVPAGFTVNVFAENLDRPRWLALTPEGDVLVTETRQNRIRRLQDQNDDGAADAVTTFADASHGLDIPFGMAFTADHFYLGNTSTLRRYPYRTGQATLQGSGEVIAELPGGGYRQHWTRNVVVSPDQQRLYVSIGSRSNVSAEPLPRASVQVMALDGSAPETVASGLRNPVGLDFHPVTGDLYTTVNERDGLGDDLVPDYLTRIQAGEFYGWPYAYLQPDWLDPRQVVDGRSRRPDLAAQTQTPDVLFQAHSAALGLQFYDGNTFPQRYHQGAFVAFRGSWNRQQGTGYKLVFVPFSSEGRPLGHYEDFLTGFLVDPQGPTTWGRPVGLLMMPDGSLLFTEEMNGRIYRVQFSQG
>NZ_CP021983.1|WP_088431613.1|2145191_2145425_-|hypothetical-protein
MSVDDTKFQQELENAVEYARQVCDQQGADSQACAVAWDTVEEMRAEVSHQHQTPAKTGFDQYLEDNPDAPEGLIYDT
>NZ_CP021983.1|WP_080813828.1|2147993_2148197_+|hypothetical-protein
MAIPLQRLLQDQFDRLGAAYTSTSRMSTAYPQARIVAEQGQLALELYQPFTRLAQMMMGYAPLTFAV
>NZ_CP021983.1|WP_080813826.1|2148700_2148961_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MPTVTVSDKGQVVIPAAIRKQLGITPGSQLTFTLEGNTIRVEVKRHKPTTTIDEGFGMLVCPPGPARRLQDFDIAQAMREDNHERP
>NZ_CP021983.1|WP_088429663.1|2148947_2149379_+|PIN-domain-containing-protein
MNALDTNILARFYVDDPNDPEAQWQRPLTRKVLAESASVFVPLSVILELEWVLRAFYGFGCQDFVQVIRHLLGLPHVTIEHWERVADALEWHLQGLDWADALHLAASRHCENLMSFDDKRFARRAQRLKLKPSVLVPGESGGE
>NZ_CP021983.1|WP_080813822.1|2149442_2149814_+|LuxR-family-transcriptional-regulator
MIEHLAHCLLESRQLFPGQPIQLQDQVSLPDETRVSLQAQWIDLGPQQASCIVVILENLTAVAHQQAQIDAWRYGLTEREAQVWERALLGLSYRDIGQELFIALNTVKRHMKSIRRKQSDGCG

Crispr_ID: NZ_CP021983_14

• CRISPR_ID: NZ_CP021983_14
• CRISPR_location: 2245320-2247343
• CRISPR_type: Unclear
• Repeat_type: I-A,I-B,II-B
• Spacer_info: 28 spacers
• Cas_protein_info: cas2,cas1,cas7,cas8b3,cas3

Consensus repeat of NZ_CP021983_14

Consensus_repeat	Method
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	CRISPRCasFinder
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	CRT
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	PILER-CR

spacers of NZ_CP021983_14

>14.1|2245355|35|NZ_CP021983|CRISPRCasFinder,CRT
GTTGAGGGCGCATCAGTCAAAACTGATCGAGGTCG
>14.2|2245425|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
CGAAGCCGCTAAACAGGGTACTGCAACGGGTATCCAG
>14.3|2245497|34|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
AGTTTTGGTCACGGTCCAGGGTACTGGCCCAGCC
>14.4|2245566|35|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
TCCATCCAGTTCCCCTTCTCTGGCAATGCCAGCCT
>14.5|2245636|38|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
GGGATGGTCGTCAGGGTGATGATAGCACCAATCCAGAT
>14.6|2245709|36|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
GGGGGCAGTGTCCCGGGACGTTCTACGACATAAGGG
>14.7|2245780|34|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
ATATAGCGCAATTCGATCGGGCGCTTCTTCGAGG
>14.8|2245849|36|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
TCTTTCAACTCCGATCGGATTTCGGGCTTCAACCTA
>14.9|2245920|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
TCCGTGCCAGCAAAAGAAATTGTCACATTTCTGTCCG
>14.10|2245992|38|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
TTTATCTCCTTGTCTAGGTTCTGTTGAGCCCCCTGAGA
>14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
TTTTCCCCCACCGCCTCCGCCTCCACCCCCTCCACCT
>14.12|2246137|36|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
ATGTCCCGATTAACTCAGTGGCTACGTCGCCACCTG
>14.13|2246208|35|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
CGTGTGTTTTCCGTGGTTGATGGCGTAGGGCAGCC
>14.14|2246278|36|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
CCCTGCGTTCTCAAGCTATCCTGTTCTTTTTTGCGG
>14.15|2246349|40|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
CCATCGTAGGCATCCCGAGAAATGTCCTTAGACGACTCCA
>14.16|2246424|34|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
ATATAGCGCAATTCGATCGGGCGCTTCTTCGAGG
>14.17|2246493|36|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
TCTTTCAACTCCGATCGGATTTCGGGCTTCAACCTA
>14.18|2246564|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
TCCGTGCCAGCAAAAGAAATTGTCACATTTCTGTCCG
>14.19|2246636|38|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
TTTATCTCCTTGTCTAGGTTCTGTTGAGCCCCCTGAGA
>14.20|2246709|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
GAAATTACTGTGAAAGACACAGAGGGAAAGTCCTATA
>14.21|2246781|36|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
GACAATCGGCCTCTGCACGTTCAGTGGCGGTGGCAC
>14.22|2246852|35|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
ATGCTTTTCTCGTGGACCGTAAACGCTAGGCCCAA
>14.23|2246922|36|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
AATCAGTAATGCCCAATTGTTCACTACCTCTTGGGT
>14.24|2246993|36|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
GCACGGATGGTACTGCGATCGCCCGAAACACTGGGC
>14.25|2247064|35|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
TGAGAACTTCATCGTACCAATGTTTCTTAGTCATC
>14.26|2247134|36|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
TAGTCCTCATCCACGTACCACTCAGGGGCGCACGTA
>14.27|2247205|35|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR
CTCCCGGGCGAGAACAGCGCGTCTACTGTTTTCTG
>14.28|2247275|34|NZ_CP021983|CRT
GAAGAACAATTCAAAATTCAAAACTCAAAACTCA

CRISPR arrays and Neighbor proteins around NZ_CP021983_14

CRISPR arrays

The CRISPR arrays of NZ_CP021983_14

>merge|NZ_CP021983|14|2245320-2247343|CRISPRCasFinder,CRT,PILER-CR
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACGTTGAGGGCGCATCAGTCAAAACTGATCGAGGTCGCCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACCGAAGCCGCTAAACAGGGTACTGCAACGGGTATCCAGCCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACAGTTTTGGTCACGGTCCAGGGTACTGGCCCAGCCCCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACTCCATCCAGTTCCCCTTCTCTGGCAATGCCAGCCTCCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACGGGATGGTCGTCAGGGTGATGATAGCACCAATCCAGATCCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACGGGGGCAGTGTCCCGGGACGTTCTACGACATAAGGGCCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACATATAGCGCAATTCGATCGGGCGCTTCTTCGAGGCCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACTCTTTCAACTCCGATCGGATTTCGGGCTTCAACCTACCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACTCCGTGCCAGCAAAAGAAATTGTCACATTTCTGTCCGCCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACTTTATCTCCTTGTCTAGGTTCTGTTGAGCCCCCTGAGACCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACTTTTCCCCCACCGCCTCCGCCTCCACCCCCTCCACCTCCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACATGTCCCGATTAACTCAGTGGCTACGTCGCCACCTGCCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACCGTGTGTTTTCCGTGGTTGATGGCGTAGGGCAGCCCCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACCCCTGCGTTCTCAAGCTATCCTGTTCTTTTTTGCGGCCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACCCATCGTAGGCATCCCGAGAAATGTCCTTAGACGACTCCACCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACATATAGCGCAATTCGATCGGGCGCTTCTTCGAGGCCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACTCTTTCAACTCCGATCGGATTTCGGGCTTCAACCTACCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACTCCGTGCCAGCAAAAGAAATTGTCACATTTCTGTCCGCCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACTTTATCTCCTTGTCTAGGTTCTGTTGAGCCCCCTGAGACCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACGAAATTACTGTGAAAGACACAGAGGGAAAGTCCTATACCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACGACAATCGGCCTCTGCACGTTCAGTGGCGGTGGCACCCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACATGCTTTTCTCGTGGACCGTAAACGCTAGGCCCAACCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACAATCAGTAATGCCCAATTGTTCACTACCTCTTGGGTCCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACGCACGGATGGTACTGCGATCGCCCGAAACACTGGGCCCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACTGAGAACTTCATCGTACCAATGTTTCTTAGTCATCCCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACTAGTCCTCATCCACGTACCACTCAGGGGCGCACGTACCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCACCTCCCGGGCGAGAACAGCGCGTCTACTGTTTTCTGCCGCCAAACCTCTGATGCCGCAAGGCTTTGAGCACGAAGAACAATTCAAAATTCAAAACTCAAAACTCATCGCCAAACCTCTGTTCGCGAAGCGTTGCCGCAGG

>NZ_CP021983|14|15|2245320-2247274|CRISPRCasFinder
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	GTTGAGGGCGCATCAGTCAAAACTGATCGAGGTCG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	CGAAGCCGCTAAACAGGGTACTGCAACGGGTATCCAG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	AGTTTTGGTCACGGTCCAGGGTACTGGCCCAGCC
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TCCATCCAGTTCCCCTTCTCTGGCAATGCCAGCCT
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	GGGATGGTCGTCAGGGTGATGATAGCACCAATCCAGAT
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	GGGGGCAGTGTCCCGGGACGTTCTACGACATAAGGG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	ATATAGCGCAATTCGATCGGGCGCTTCTTCGAGG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TCTTTCAACTCCGATCGGATTTCGGGCTTCAACCTA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TCCGTGCCAGCAAAAGAAATTGTCACATTTCTGTCCG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TTTATCTCCTTGTCTAGGTTCTGTTGAGCCCCCTGAGA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TTTTCCCCCACCGCCTCCGCCTCCACCCCCTCCACCT
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	ATGTCCCGATTAACTCAGTGGCTACGTCGCCACCTG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	CGTGTGTTTTCCGTGGTTGATGGCGTAGGGCAGCC
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	CCCTGCGTTCTCAAGCTATCCTGTTCTTTTTTGCGG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	CCATCGTAGGCATCCCGAGAAATGTCCTTAGACGACTCCA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	ATATAGCGCAATTCGATCGGGCGCTTCTTCGAGG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TCTTTCAACTCCGATCGGATTTCGGGCTTCAACCTA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TCCGTGCCAGCAAAAGAAATTGTCACATTTCTGTCCG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TTTATCTCCTTGTCTAGGTTCTGTTGAGCCCCCTGAGA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	GAAATTACTGTGAAAGACACAGAGGGAAAGTCCTATA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	GACAATCGGCCTCTGCACGTTCAGTGGCGGTGGCAC
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	ATGCTTTTCTCGTGGACCGTAAACGCTAGGCCCAA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	AATCAGTAATGCCCAATTGTTCACTACCTCTTGGGT
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	GCACGGATGGTACTGCGATCGCCCGAAACACTGGGC
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TGAGAACTTCATCGTACCAATGTTTCTTAGTCATC
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TAGTCCTCATCCACGTACCACTCAGGGGCGCACGTA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	CTCCCGGGCGAGAACAGCGCGTCTACTGTTTTCTG
CCGCCAAACCTCTGATGCCGCAAGGCTTTGAGCAC

>NZ_CP021983|14|5|2245320-2247343|CRT
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	GTTGAGGGCGCATCAGTCAAAACTGATCGAGGTCG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	CGAAGCCGCTAAACAGGGTACTGCAACGGGTATCCAG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	AGTTTTGGTCACGGTCCAGGGTACTGGCCCAGCC
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TCCATCCAGTTCCCCTTCTCTGGCAATGCCAGCCT
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	GGGATGGTCGTCAGGGTGATGATAGCACCAATCCAGAT
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	GGGGGCAGTGTCCCGGGACGTTCTACGACATAAGGG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	ATATAGCGCAATTCGATCGGGCGCTTCTTCGAGG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TCTTTCAACTCCGATCGGATTTCGGGCTTCAACCTA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TCCGTGCCAGCAAAAGAAATTGTCACATTTCTGTCCG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TTTATCTCCTTGTCTAGGTTCTGTTGAGCCCCCTGAGA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TTTTCCCCCACCGCCTCCGCCTCCACCCCCTCCACCT
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	ATGTCCCGATTAACTCAGTGGCTACGTCGCCACCTG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	CGTGTGTTTTCCGTGGTTGATGGCGTAGGGCAGCC
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	CCCTGCGTTCTCAAGCTATCCTGTTCTTTTTTGCGG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	CCATCGTAGGCATCCCGAGAAATGTCCTTAGACGACTCCA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	ATATAGCGCAATTCGATCGGGCGCTTCTTCGAGG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TCTTTCAACTCCGATCGGATTTCGGGCTTCAACCTA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TCCGTGCCAGCAAAAGAAATTGTCACATTTCTGTCCG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TTTATCTCCTTGTCTAGGTTCTGTTGAGCCCCCTGAGA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	GAAATTACTGTGAAAGACACAGAGGGAAAGTCCTATA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	GACAATCGGCCTCTGCACGTTCAGTGGCGGTGGCAC
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	ATGCTTTTCTCGTGGACCGTAAACGCTAGGCCCAA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	AATCAGTAATGCCCAATTGTTCACTACCTCTTGGGT
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	GCACGGATGGTACTGCGATCGCCCGAAACACTGGGC
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TGAGAACTTCATCGTACCAATGTTTCTTAGTCATC
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TAGTCCTCATCCACGTACCACTCAGGGGCGCACGTA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	CTCCCGGGCGAGAACAGCGCGTCTACTGTTTTCTG
CCGCCAAACCTCTGATGCCGCAAGGCTTTGAGCAC	GAAGAACAATTCAAAATTCAAAACTCAAAACTCA
TCGCCAAACCTCTGTTCGCGAAGCGTTGCCGCAGG

>NZ_CP021983|14|5|2245390-2247274|PILER-CR
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	CGAAGCCGCTAAACAGGGTACTGCAACGGGTATCCAG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	AGTTTTGGTCACGGTCCAGGGTACTGGCCCAGCC
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TCCATCCAGTTCCCCTTCTCTGGCAATGCCAGCCT
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	GGGATGGTCGTCAGGGTGATGATAGCACCAATCCAGAT
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	GGGGGCAGTGTCCCGGGACGTTCTACGACATAAGGG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	ATATAGCGCAATTCGATCGGGCGCTTCTTCGAGG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TCTTTCAACTCCGATCGGATTTCGGGCTTCAACCTA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TCCGTGCCAGCAAAAGAAATTGTCACATTTCTGTCCG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TTTATCTCCTTGTCTAGGTTCTGTTGAGCCCCCTGAGA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TTTTCCCCCACCGCCTCCGCCTCCACCCCCTCCACCT
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	ATGTCCCGATTAACTCAGTGGCTACGTCGCCACCTG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	CGTGTGTTTTCCGTGGTTGATGGCGTAGGGCAGCC
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	CCCTGCGTTCTCAAGCTATCCTGTTCTTTTTTGCGG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	CCATCGTAGGCATCCCGAGAAATGTCCTTAGACGACTCCA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	ATATAGCGCAATTCGATCGGGCGCTTCTTCGAGG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TCTTTCAACTCCGATCGGATTTCGGGCTTCAACCTA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TCCGTGCCAGCAAAAGAAATTGTCACATTTCTGTCCG
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TTTATCTCCTTGTCTAGGTTCTGTTGAGCCCCCTGAGA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	GAAATTACTGTGAAAGACACAGAGGGAAAGTCCTATA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	GACAATCGGCCTCTGCACGTTCAGTGGCGGTGGCAC
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	ATGCTTTTCTCGTGGACCGTAAACGCTAGGCCCAA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	AATCAGTAATGCCCAATTGTTCACTACCTCTTGGGT
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	GCACGGATGGTACTGCGATCGCCCGAAACACTGGGC
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TGAGAACTTCATCGTACCAATGTTTCTTAGTCATC
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	TAGTCCTCATCCACGTACCACTCAGGGGCGCACGTA
CCGCCAAACCTCTGATGCCGCAAGGCGTTGAGCAC	CTCCCGGGCGAGAACAGCGCGTCTACTGTTTTCTG
CCGCCAAACCTCTGATGCCGCAAGGCTTTGAGCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_080809751.1|2249438_2249684_+|hypothetical-protein	unknown	unknown	gnl|CDD|377095
NZ_CP021983.1|WP_080809754.1|2249676_2250180_+|DUF3368-domain-containing-protein	unknown	unknown	gnl|CDD|225269
NZ_CP021983.1|WP_080809748.1|2247756_2247951_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl|CDD|224514
NZ_CP021983.1|WP_080809732.1|2239205_2240876_+|type-I-MYXAN-CRISPR-associated-protein-Cmx8	cas8b3	mkCas0177_cas8b3_CAS-I-B	gnl|CDD|275206
NZ_CP021983.1|WP_080809742.1|2243100_2244768_+|type-I-MYXAN-CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|274899
NZ_CP021983.1|WP_080809744.1|2244777_2245071_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|378256
NZ_CP021983.1|WP_088429726.1|2247410_2247809_+|DUF2283-domain-containing-protein	unknown	unknown	gnl|CDD|378367
NZ_CP021983.1|WP_088429728.1|2250792_2251137_-|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|143393
NZ_CP021983.1|WP_080809765.1|2252287_2254318_-|molybdate-ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|224043
NZ_CP021983.1|WP_088431625.1|2235792_2238198_+|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	gnl|CDD|350688
NZ_CP021983.1|WP_080809736.1|2241796_2242537_+|type-I-MYXAN-CRISPR-associated-protein-Cas5/Cmx5/DevS	unknown	unknown	gnl|CDD|274218
NZ_CP021983.1|WP_088429724.1|2238708_2239203_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080809757.1|2250285_2250483_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088431532.1|2248139_2249200_-|IS630-family-transposase	unknown	unknown	gnl|CDD|315923
NZ_CP021983.1|WP_088429730.1|2251348_2251921_+|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NZ_CP021983.1|WP_080809734.1|2240902_2241784_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl|CDD|187818
NZ_CP021983.1|WP_080809748.1|2250489_2250684_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl|CDD|224514
NZ_CP021983.1|WP_080809739.1|2242552_2242789_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080809727.1|2238202_2238421_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080809729.1|2238404_2238680_-|BrnT-family-toxin	unknown	unknown	gnl|CDD|367913

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP021983.1|WP_080809732.1|2239205_2240876_+|type-I-MYXAN-CRISPR-associated-protein-Cmx8	cas8b3	mkCas0177_cas8b3_CAS-I-B	1.1e-207	685.7	1.0
NZ_CP021983.1|WP_088431625.1|2235792_2238198_+|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	2e-47	156.6	0.0
NZ_CP021983.1|WP_080809734.1|2240902_2241784_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	1.4e-25	84.8	0.0
NZ_CP021983.1|WP_080809742.1|2243100_2244768_+|type-I-MYXAN-CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	1.1e-92	305.1	0.0
NZ_CP021983.1|WP_080809744.1|2244777_2245071_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	1e-21	71.8	0.4

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_080809754.1|2249676_2250180_+|DUF3368-domain-containing-protein	gnl|CDD|225269	COG2405, COG2405, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	1.5727e-26
NZ_CP021983.1|WP_080809748.1|2247756_2247951_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl|CDD|224514	COG1598, COG1598, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	1.94908e-07
NZ_CP021983.1|WP_080809742.1|2243100_2244768_+|type-I-MYXAN-CRISPR-associated-endonuclease-Cas1	gnl|CDD|274899	TIGR03983, hypothetical_protein_LA3181, CRISPR-associated endonuclease Cas1, subtype MYXAN. Members of this protein are the Cas1 endonuclease, or Cas1 domain in Cas4/Cas1 fusion proteins, of the MYXAN subtype of CRISPR/Cas systems. These systems typically feature repeats and spacers each about 36 base pairs in length. Species with this type of CRISPR system include Myxococcus xanthus, Cyanothece sp., Leptospira interrogans, Sorangium cellulosum, Anabaena variabilis ATCC 29413, etc.	0
NZ_CP021983.1|WP_080809732.1|2239205_2240876_+|type-I-MYXAN-CRISPR-associated-protein-Cmx8	gnl|CDD|275206	TIGR04413, hypothetical_protein_LEP1GSC082_4029, CRISPR type MYXAN-associated protein Cmx8. Members of this family occur only in CRISPR/cas loci of the MYXAN type, but are present in a minority of such systems. This protein appears to replace the MYXAN system Cas8a1/Csx13 protein (TIGR03485/TIGR03486), compared to which it shows similar length and composition but only about 12 percent sequence identity.	0
NZ_CP021983.1|WP_080809744.1|2244777_2245071_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	4.71374e-18
NZ_CP021983.1|WP_088429726.1|2247410_2247809_+|DUF2283-domain-containing-protein	gnl|CDD|378367	pfam10049, DUF2283, Protein of unknown function (DUF2283). Members of this family of hypothetical bacterial proteins have no known function.	4.72445e-15
NZ_CP021983.1|WP_088429728.1|2250792_2251137_-|nucleotidyltransferase-domain-containing-protein	gnl|CDD|143393	cd05403, NT_KNTase_like, Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins. S. aureus KNTase is a plasmid encoded enzyme which confers resistance to a wide range of aminoglycoside antibiotics which have a 4'- or 4''-hydroxyl group in the equatorial position, such as kanamycin A. This enzyme transfers a nucleoside monophosphate group from a nucleotide (ATP,GTP, or UTP) to the 4'-hydroxyl group of kanamycin A. This enzyme is a homodimer, having two NT active sites. The nucleotide and antibiotic binding sites of each active site include residues from each monomer. Included in this subgroup is Escherichia coli AadA5 which confers resistance to the antibiotic spectinomycin and is a putative aminoglycoside-3'-adenylyltransferase. It is part of the aadA5 cassette of a class 1 integron. This subgroup also includes Haemophilus influenzae HI0073 which forms a 2:2 heterotetramer with an unrelated protein HI0074. Structurally HI0074 is related to the substrate-binding domain of S. aureus KNTase. The genes encoding HI0073 and HI0074 form an operon. Little is known about the substrate specificity or function of two-component NTs. The characterized members of this subgroup may not be representive of the function of this subgroup. This subgroup belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, co-ordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are conserved in this subgroup.	1.03812e-13
NZ_CP021983.1|WP_080809765.1|2252287_2254318_-|molybdate-ABC-transporter-permease-subunit	gnl|CDD|224043	COG1118, CysA, ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism].	4.0316e-110
NZ_CP021983.1|WP_088431625.1|2235792_2238198_+|CRISPR-associated-helicase-Cas3'	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.65979e-42
NZ_CP021983.1|WP_080809736.1|2241796_2242537_+|type-I-MYXAN-CRISPR-associated-protein-Cas5/Cmx5/DevS	gnl|CDD|274218	TIGR02593, CRISPR-associated_protein_Cas5, CRISPR-associated protein Cas5, N-terminal domain. This model represents a shared N-terminal domain, about 43 amino acids in length, common to a number of related protein families each of which is associated with a distinct subtype of CRISPR/cas system, where CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeat and Cas is an abbreviation for CRISPR-associated. Members of this family are widely distributed enough that we designated the family Cas5. Homology appears remote, or absent, between the more C-terminal regions different subfamilies of these proteins, which typically are 210 to 265 amino acids in total length. Cas5 proteins of six different CRISPR/cas subtypes so far defined are described by respective full-length models TIGR01868, TIGR01876, TIGR01895, TIGR01874, TIGR02586, and TIGR02592. The best characterized protein in this family is DevS or Myxococcus xanthus, a Cas protein that appears to participate in a species-specific developmental pathway.	9.19165e-08
NZ_CP021983.1|WP_080809751.1|2249438_2249684_+|hypothetical-protein	gnl|CDD|377095	pfam03683, UPF0175, Uncharacterized protein family (UPF0175). This family contains small proteins of unknown function.	2.48894e-20
NZ_CP021983.1|WP_088431532.1|2248139_2249200_-|IS630-family-transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.97716e-29
NZ_CP021983.1|WP_088429730.1|2251348_2251921_+|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	6.026e-35
NZ_CP021983.1|WP_080809734.1|2240902_2241784_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl|CDD|187818	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cst2/DevR family.	2.2682e-16
NZ_CP021983.1|WP_080809748.1|2250489_2250684_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl|CDD|224514	COG1598, COG1598, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	1.94908e-07
NZ_CP021983.1|WP_080809729.1|2238404_2238680_-|BrnT-family-toxin	gnl|CDD|367913	pfam04365, BrnT_toxin, Ribonuclease toxin, BrnT, of type II toxin-antitoxin system. BrnT is a ribonuclease toxin of a type II toxin-antitoxin system that exhibits a RelE-like fold. The antitoxin that neutralizes this toxin is pfam14384. BrnT is found in bacteria, archaea, bacteriophage, and plasmids. BrnT-BrnA forms a 2:2 tetrameric complex and autoregulates its own expression, which is induced by a number of different environmental stresses. Expression of BrnT alone results in cessation of bacterial growth which can be rescued after subsequent expression of BrnA.	1.02966e-32

Protein sequences

>NZ_CP021983.1|WP_080809744.1|2244777_2245071_+|CRISPR-associated-endonuclease-Cas2
MAESKNYYLICYDIRDPKRWRRAYKLLKGYGETIQYSIFRVRLNQREREQLRWKLEKILTEEDSLLIAGLCQRCVERIEACNRPESWEVEHDMHQIL
>NZ_CP021983.1|WP_080809742.1|2243100_2244768_+|type-I-MYXAN-CRISPR-associated-endonuclease-Cas1
MTTSLIKPAINSRDTIRVNALHALAYCPRLYYLEDVEELYTQDAAVFAGRRLHVELEKGEDEEWVHLVLESADLGLRGKVDALKTRNRQTIPYEHKRGRCYRDRDNKPQPWQSDRIQILAYACLIEAALGITVPEGRIRYHADNVLVHVLLDDQGRQEVREAVARAWQLRQSTQRPPVTSNERLCARCSLAPVCLPEETRLVQGQSHQPRRLFPEDDERKIIHVTEAGTRISKSGDQFKITKRDGDATAIPSRQVGQLVLHSYAQISTQAIYFCADQEVGLHFISGGGRYLGSFDTRQGSIQRRIRQYEALTQPEVCLKLARQLVVCRGQSQRKFLMRGQRSLEVANHALEQAIDQMQRTLKQVPKAESATSLLGLEGNLAALYFGALPHLIAENAVADFQFDGRNRRPPKDRINAMLSFGYALLLKDVMNAILTVGLEPALGFYHQPRTQAPPLALDLMEIFRVPLVDMPVMASVNRNQWDIADDFIRRGEQVWLSDSGRRKFISLYERRKEESWKHPVTHYSLTYRRLIELEVRLLEKEWMDEGGLFAQLVIR
>NZ_CP021983.1|WP_080809739.1|2242552_2242789_+|hypothetical-protein
MSSLSISGEVLAGLTTIAQQFNLSVEELLTRISQGKLAIIDADELEDLLDIRDAALAESDAENQERVPWQAVKQELDL
>NZ_CP021983.1|WP_080809736.1|2241796_2242537_+|type-I-MYXAN-CRISPR-associated-protein-Cas5/Cmx5/DevS
MDNLWLRIRAPFAAFRGFQAGVYRATAPVMPPSAAFGLVLNLAGIEMRDSKQEPTTLIRQDLPCLRLAIGVPNKQLPNGEAVPETESEVCSLYQQLHSYPVGSSGKELRKRTHGAKYWIVPVRREFLVGFDIMLGIQTQASDLLEKVIQGLRGDFNESRYGLPFAGDNNFLFDRIDVVDSPPPTLWYVQMQPDDPPLRGSYRLTVGIDRADNSKTTSHLYAPLEEAITEPPELAWTWTPKEPVRAA
>NZ_CP021983.1|WP_080809734.1|2240902_2241784_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MMHKNLFATVLTYPAPSSNYRGESEENRTVLQKIAKGRQEYTVISPESMRNALREMLQKTGIPCNRSRLQDEDQLAVEFKEFPNAEKYADDFLFGFLVADKEAIKKNKGLPAKRDSVLRMNMAVALTPYRFDATFHQSPLNAGNSPWKNSSTSALLHREVAHTAYQYPFALAYSDCKAKPEWTKALLQAISQLSDVAGGHARSYYEMAPKSIVARLTPSLIAGFDTYGFDEQGKFSELARIHDNDLPADEFWIGGELSRNMDETRKEELAQVGVKFYDNPQTLLADLAEEFLK
>NZ_CP021983.1|WP_080809732.1|2239205_2240876_+|type-I-MYXAN-CRISPR-associated-protein-Cmx8
MVKNKTKGEVDALTLNYRLAELPSSQHRAGLAGLVCIIRWLERQPDFQEETANGTICKLTRLDDLGASIELNQAGVEALFNEIYAASTEEQERPQLLKNKQKEIIPPLREEEREVTDKKGKTKTKKVYIYPVVVPAGSFLADPAYDKSVEGKNGLWIKLWRDMVWSILRGVPATRKPFEARAEGSYGDDAASIWKQLTQPEDYTVDLPSTYFLGAQSSNAENVPFKDRARLQFLLHFWLFAAQIYVPAVVDNEGKRDFVGYALAIPDVARLEWFCDELPEILSDRSTERSRYRPRDAVVDLAVASALDMMKRLRDRLKQKTGEKLAEDLVFGIDVIHTEKQGNNIRVLSSTRLDPEESMLDEYAQIRDGFWSPLFRKQCLLNLVDDKPWYTKFDVLLCTLPYERTIEDRYFQRDVREKLKALSQKEKQMDETTAVDNSVSIETLVFRLVGNYVTRKLKSKHELEWKAEWKGLKNEELNQKADYKKYSEMKAKVAKSAFLDVRSRTEPMDFINYFVSSLCSVPQHMKSTAYVALTQALYQDTDKVRTLTLLALSANG
>NZ_CP021983.1|WP_088429724.1|2238708_2239203_+|hypothetical-protein
MARQQHISTFDILVRLSMMPLALSTEPRGMLNTSRMDNHRCRKALMPTLQGISEEVGISQKIGIVCERRDIRLSLLEAAMTTEQLSLLDHATQLLSEQRIPYEVDTATAAKLLRISVSTLNRAKNARKLPYKREIDGYCASASFVGNPKRKDLWLITFKKIGGA
>NZ_CP021983.1|WP_080809729.1|2238404_2238680_-|BrnT-family-toxin
MQFQWDGQKASANHRKHSVTFEEAVTVFGDPLAITISDPQHSRDEARWLTIGLSLSGRLLVVSYTERDNSVRVISARLATRRERSDYESGN
>NZ_CP021983.1|WP_080809727.1|2238202_2238421_-|hypothetical-protein
MNPETDPNSTDDMLPEYDFSGGVRGKHYEAYQKSTNIVVLDPDVAEIFKDSAAVNEALRMLAKVAKSLPAET
>NZ_CP021983.1|WP_088431625.1|2235792_2238198_+|CRISPR-associated-helicase-Cas3'
MPELPDQLLAKSPRPGRKPVTLEEHLQDTAVCAAQIFRLNGRWGQNWCRFFQISTAEEQFLLNLQVAALFHDLGKANEDFYAAVSQPGFTQQTIRHEHLSALMLCLPEVRNWLSQDSRLDANIITAAVLSHHLKAFDDSTSVKDKERSERIKNYRWGHVQTLKQSVVLYLQHEEVTATLQRIVDLTDLQEIPSLPKTAWRPASEWEQAWRKGKKQFAPSFKRDLRKNTQRRSLLIAVKAGLILSDAAASGLVREGYDISDWIEAIVHSEAIAANEISEKILLPWIQQIEQRTKKPFKFHAFQEQAAEQGKKALLLVACGGGKTLAAWKWAEQQTQKYNIGKVIFLYPTRGTATEGFRDYVGWAPEADAALVTGTAKYELEAMAENPSESIADKVFRTEADERLYALSFWSKRFFSATVDQFLSFMEHSYQSLCLLPVLADSAVIIDEVHSFDRSMFDILISFLNTFHIPVLCMTATLPQSRRDELVKAGLKVFPTATDRASEALADLKELEQADRYWLEPVADFSVAFDKAVTAYQAGLRVLWVVNTVDRCLAIAQKLEAVLDGGVLTYHSRFRLRDRQKVHANTVKAFSFSEGDVPKRAIAVTTQVCEMSLDLDADVLITEIAPVSSLVQRFGRANRHLKRSFATLHPYMPPANLPYQRNDLETANAFLESFETELVSQLQLATALEIYARPERDADGSSSFLNSGYYAVPGSFRDTDEFAIPCILDSDLDAIESLVKDRQPYDGFIVNVPHKWAKAWLEDGNPRPEWLPKYLNVVSGAADRYQVNRGFITKSPEEVELG
>NZ_CP021983.1|WP_088429726.1|2247410_2247809_+|DUF2283-domain-containing-protein
MKIIYDPEVDVLRILFRETPISESDADESGIIFDLDAQGNVVGLEILDASQRIDDPTSVSYRVAKLTEAEVASAEDTLQNLLMDPDAGKPVKEAIQQQLLQMRGRREKRTLSLENAMEALSLPSDSDIPPES
>NZ_CP021983.1|WP_080809748.1|2247756_2247951_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MRSHPDDTIVLQPDDNGTFVAYVPAIPGCHAWGQTPEVAQRELANVFVMIREEYLNQTASSALP
>NZ_CP021983.1|WP_088431532.1|2248139_2249200_-|IS630-family-transposase
MNSFQLEHQQKVDNRAILSDFISSNPDSRELKRALAVKMALEGEPYFKITKFLGINKSFITYWKNRFEAQGIEGIKLGYQGSKSYLTPDDRTEIISWLRTRNYWNFDELVSYLDEHYDVIYKSKQSYYTLFSEAGISWKKSQKTNPKSDPALVKKKREEIQGFIRQNQFKIESGELIVLFLDECHLLWGDVCGYVWGKTDMRIEIPITNERIRQTYYGALNYQTKEFILHPYEKGNGENTVAFMKYLQEQNPGKQIALIWDGASYHKSQEIKDFLATVNHGKEETEWQFKCILFAPNSPEQNPVEDVWLQAKNSLRRFWRLCRSFPAVKYLFEFFIDHQKFDFSKIEEYSPCS
>NZ_CP021983.1|WP_080809751.1|2249438_2249684_+|hypothetical-protein
MVQVTVNVPEEFLANRDADTFARQMQLAAAIYWYARGEVSMGKAAEFAGLNRPEFLDILAHEKIDVFQVDFDDLERELSRD
>NZ_CP021983.1|WP_080809754.1|2249676_2250180_+|DUF3368-domain-containing-protein
MTDAALPPIINTSPLIFLTKADLLSLLQIRYATVLVPDIVVQEIRQYGPLDNTAQILQKTDWLTVVETPPPLSPDLQACNLDAGEASVLAWACAHPPTEAILDDLAGRRCAHKLGIPIRGTLGLVLAAKQQGHIPAAKPVILKLRETGMYLSDRVINKALALVEETL
>NZ_CP021983.1|WP_080809757.1|2250285_2250483_+|hypothetical-protein
MQDGETLSLVEKLIRELGGSDCKFKRAVIVAIADSNAQMQVNLSKKRFSNSYCRCVGAVKNAHYP
>NZ_CP021983.1|WP_080809748.1|2250489_2250684_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MRSHPDDTIVLQPDDNGTFVAYVPAIPGCHAWGQTPEVAQRELANVFVMIREEYLNQTASSALP
>NZ_CP021983.1|WP_088429728.1|2250792_2251137_-|nucleotidyltransferase-domain-containing-protein
MSKIAPDLSVAHWLNVMINRIVERFQPLKIILFGSYARGEATADSDIDLLVVMPTVTSKRRKAVEIGQVLADLPVSKDIVVTTPEDIEVYGQLVGTILRPALRDGKILYERTAS
>NZ_CP021983.1|WP_088429730.1|2251348_2251921_+|Uma2-family-endonuclease
MVNTTTQPLTFEEYLTYSDGSDNRYELVDGQLVLMNPPRTEHLLITKFLEKQFDTEIQRLSLSWVTFREAGVRTGFNKSRLTDLCIVTREQARELLGQSAVFQTAPQLIVEVVSPDSITRDYRYKRSEYAALEVPEYWIVDPLEAKVTLLRWEEGLYEETVFTGEQAITSPNLPGLHLNVTQVLDASTLS
>NZ_CP021983.1|WP_080809765.1|2252287_2254318_-|molybdate-ABC-transporter-permease-subunit
MPDDLTPLWISLKTASVATVLATCLGILAAGWMLSYRGRARGLIDGVLTLPLVLPPTVVGFLLLLLLGKNSPIGQALNYLGVSPIFTWTAAVMAATVVAFPLVYKTVLSALEQLDSTLISSARTLGASDWRIFWQILLPLVWPGILAGMILAFARALGEFGATLMVGGSISGVTQTIPIAIFFAAEAGRMGVALAWVVLMVLISLVVITGIHQGSRNALPRTVLPQAGAQRLFNWIYFGTLKVNQFGLIPAVLTQQRRRLGHPSAQTTRALARSRSPNGRGRVPVDTAAREPGLPQLAVEAFPAPQTMTTPSSNSPTQPQAAELVVQIERQVPGFDLDLQFRTDQQPLGLLGASGSGKTMTLRCIAGLDTPSQGRIVLNGRVLFDSHKRINLPSCDRNVGIVFQNYALFPHLTVAQNIAFGMAAIPKPQRAADVVQYLDMMDLSGLGDRYPHQLSGGQQQRVALARALAIQPDMLLLDEPLSALDTYLRSHVEKLLVEVLSEYRGITLFITHKLEEAYRICTNLLVLANGRILANGTKEAIFQRPPSIEVAKVSECKNFSRARRVDDTHIEAIDWTCQLAVQAPIPADLAYVGLRAHHIQFVFPGEQPNTFPSWLAILTETQHRVTLYLKLHGQPSGPHDYHLQAEVYREKWDRLRHSPFPWYICLDPARLIVMPE

Crispr_ID: NZ_CP021983_15

• CRISPR_ID: NZ_CP021983_15
• CRISPR_location: 2291345-2291594
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 3 spacers
• Cas_protein_info: csx1,cmr5gr11,cas1,cas2

Consensus repeat of NZ_CP021983_15

Consensus_repeat	Method
CCTTCCCACTCAGT-GGGAAACTAATTGAATGGAAAC	PILER-CR
CCTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	CRT
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	CRISPRCasFinder

spacers of NZ_CP021983_15

>15.1|2291381|34|NZ_CP021983|PILER-CR,CRT
AGGATAAAGTATCCTCTAATGTGAAACTCTCTCT
>15.2|2291451|35|NZ_CP021983|PILER-CR,CRT
TCGCGGCGATCCGTGGAACCGAAGCGGAAGAACTG
>15.3|2291522|37|NZ_CP021983|PILER-CR,CRT
GGTCGTACCCTGCCTCCTCGGCCGCTTTCTCGGTGGC
>15.4|2291381|35|NZ_CP021983|CRISPRCasFinder
AGGATAAAGTATCCTCTAATGTGAAACTCTCTCTT
>15.5|2291451|36|NZ_CP021983|CRISPRCasFinder
TCGCGGCGATCCGTGGAACCGAAGCGGAAGAACTGC
>15.6|2291522|38|NZ_CP021983|CRISPRCasFinder
GGTCGTACCCTGCCTCCTCGGCCGCTTTCTCGGTGGCC

CRISPR arrays and Neighbor proteins around NZ_CP021983_15

CRISPR arrays

The CRISPR arrays of NZ_CP021983_15

>merge|NZ_CP021983|15|2291345-2291594|PILER-CR,CRT,CRISPRCasFinder
CCTTCCCACTCAGTGGGAAACTAATTGAATGGAAACAGGATAAAGTATCCTCTAATGTGAAACTCTCTCTTCTTCCCACTCAGTGGGAAACTAATTGAATGGAAACTCGCGGCGATCCGTGGAACCGAAGCGGAAGAACTGCCTTCCCACTCAGTGGGAAACTAATTGAATGGAAACGGTCGTACCCTGCCTCCTCGGCCGCTTTCTCGGTGGCCCTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC

>NZ_CP021983|15|6|2291345-2291594|PILER-CR
CCTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	AGGATAAAGTATCCTCTAATGTGAAACTCTCTCT
TCTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	TCGCGGCGATCCGTGGAACCGAAGCGGAAGAACTG
CCTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	GGTCGTACCCTGCCTCCTCGGCCGCTTTCTCGGTGGC
CCTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC

>NZ_CP021983|15|6|2291345-2291594|CRT
CCTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	AGGATAAAGTATCCTCTAATGTGAAACTCTCTCT
TCTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	TCGCGGCGATCCGTGGAACCGAAGCGGAAGAACTG
CCTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	GGTCGTACCCTGCCTCCTCGGCCGCTTTCTCGGTGGC
CCTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC

>NZ_CP021983|15|16|2291346-2291594|CRISPRCasFinder
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	AGGATAAAGTATCCTCTAATGTGAAACTCTCTCTT
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	TCGCGGCGATCCGTGGAACCGAAGCGGAAGAACTGC
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	GGTCGTACCCTGCCTCCTCGGCCGCTTTCTCGGTGGCC
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_088429766.1|2301926_2303111_+|transaldolase	unknown	unknown	gnl|CDD|183426
NZ_CP021983.1|WP_088429774.1|2309246_2309933_-|KR-domain-containing-protein	unknown	unknown	gnl|CDD|235546
NZ_CP021983.1|WP_080813411.1|2288991_2289210_-|hypothetical-protein	unknown	unknown	gnl|CDD|377095
NZ_CP021983.1|WP_088429762.1|2289695_2290115_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088429770.1|2304406_2306092_+|alpha-glucosidase	unknown	unknown	gnl|CDD|200472
NZ_CP021983.1|WP_080813406.1|2294247_2294526_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NZ_CP021983.1|WP_080813413.1|2288542_2288995_-|DUF3368-domain-containing-protein	unknown	unknown	gnl|CDD|225269
NZ_CP021983.1|WP_080813426.1|2281597_2282050_+|hypothetical-protein	cmr5gr11	mkCas0065_cmr5gr11_CAS-III-B	unknown
NZ_CP021983.1|WP_080813419.1|2286321_2286645_+|DUF433-domain-containing-protein	unknown	unknown	gnl|CDD|377269
NZ_CP021983.1|WP_080814380.1|2308274_2309138_-|inositol-monophosphatase-family-protein	unknown	unknown	gnl|CDD|238815
NZ_CP021983.1|WP_088429772.1|2306241_2308269_+|glycogen-debranching-protein	unknown	unknown	gnl|CDD|283786
NZ_CP021983.1|WP_080813407.1|2293250_2294243_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|376633
NZ_CP021983.1|WP_088429760.1|2287035_2288472_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080813425.1|2282033_2283728_+|RAMP-superfamily-protein	unknown	unknown	gnl|CDD|213662
NZ_CP021983.1|WP_088429756.1|2283864_2285352_+|hypothetical-protein	csx1	mkCas0108_csx1_CAS-III	unknown
NZ_CP021983.1|WP_088429758.1|2285611_2285920_-|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl|CDD|198403
NZ_CP021983.1|WP_080813417.1|2286649_2287012_+|hypothetical-protein	unknown	unknown	gnl|CDD|375906
NZ_CP021983.1|WP_088431631.1|2297065_2299498_+|endonuclease-MutS2	unknown	unknown	gnl|CDD|234750
NZ_CP021983.1|WP_088429764.1|2299505_2300951_-|deoxyribodipyrimidine-photolyase	unknown	unknown	gnl|CDD|274644
NZ_CP021983.1|WP_088429768.1|2303193_2303997_+|3-oxoacyl-ACP-reductase	unknown	unknown	gnl|CDD|187616

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP021983.1|WP_080813407.1|2293250_2294243_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	9.6e-85	279.1	0.0
NZ_CP021983.1|WP_088429756.1|2283864_2285352_+|hypothetical-protein	csx1	mkCas0108_csx1_CAS-III	1.3e-90	299.4	5.9
NZ_CP021983.1|WP_080813406.1|2294247_2294526_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	1.9e-28	93.2	0.0
NZ_CP021983.1|WP_080813426.1|2281597_2282050_+|hypothetical-protein	cmr5gr11	mkCas0065_cmr5gr11_CAS-III-B	3.7e-64	209.0	1.5

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_088429770.1|2304406_2306092_+|alpha-glucosidase	gnl|CDD|200472	cd11333, AmyAc_SI_OligoGlu_DGase, Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins. The sucrose isomerases (SIs) Isomaltulose synthase (EC 5.4.99.11) and Trehalose synthase (EC 5.4.99.16) catalyze the isomerization of sucrose and maltose to produce isomaltulose and trehalulose, respectively. Oligo-1,6-glucosidase (EC 3.2.1.10) hydrolyzes the alpha-1,6-glucosidic linkage of isomaltooligosaccharides, pannose, and dextran. Unlike alpha-1,4-glucosidases (EC 3.2.1.20), it fails to hydrolyze the alpha-1,4-glucosidic bonds of maltosaccharides. Dextran glucosidase (DGase, EC 3.2.1.70) hydrolyzes alpha-1,6-glucosidic linkages at the non-reducing end of panose, isomaltooligosaccharides and dextran to produce alpha-glucose.The common reaction chemistry of the alpha-amylase family enzymes is based on a two-step acid catalytic mechanism that requires two critical carboxylates: one acting as a general acid/base (Glu) and the other as a nucleophile (Asp). Both hydrolysis and transglycosylation proceed via the nucleophilic substitution reaction between the anomeric carbon, C1 and a nucleophile. Both enzymes contain the three catalytic residues (Asp, Glu and Asp) common to the alpha-amylase family as well as two histidine residues which are predicted to be critical to binding the glucose residue adjacent to the scissile bond in the substrates. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
NZ_CP021983.1|WP_088429774.1|2309246_2309933_-|KR-domain-containing-protein	gnl|CDD|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	2.25803e-51
NZ_CP021983.1|WP_080813411.1|2288991_2289210_-|hypothetical-protein	gnl|CDD|377095	pfam03683, UPF0175, Uncharacterized protein family (UPF0175). This family contains small proteins of unknown function.	3.37825e-16
NZ_CP021983.1|WP_080813406.1|2294247_2294526_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	7.93945e-30
NZ_CP021983.1|WP_088429764.1|2299505_2300951_-|deoxyribodipyrimidine-photolyase	gnl|CDD|274644	TIGR03556, photolyase_8HDF, deoxyribodipyrimidine photo-lyase, 8-HDF type. This model describes a narrow clade of cyanobacterial deoxyribodipyrimidine photo-lyase. This group, in contrast to several closely related proteins, uses a chromophore that, in other lineages is modified further to become coenzyme F420. This chromophore is called 8-HDF in most articles on the DNA photolyase and FO in most literature on coenzyme F420. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP021983.1|WP_080813419.1|2286321_2286645_+|DUF433-domain-containing-protein	gnl|CDD|377269	pfam04255, DUF433, Protein of unknown function (DUF433).	6.9739e-06
NZ_CP021983.1|WP_080814380.1|2308274_2309138_-|inositol-monophosphatase-family-protein	gnl|CDD|238815	cd01637, IMPase_like, Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1,6-bisphosphate, inositol poly- and monophosphates, PAP and PAPS, sedoheptulose-1,7-bisphosphate and probably others.	1.27422e-27
NZ_CP021983.1|WP_088429772.1|2306241_2308269_+|glycogen-debranching-protein	gnl|CDD|283786	pfam06202, GDE_C, Amylo-alpha-1,6-glucosidase. This family includes human glycogen branching enzyme AGL. This enzyme contains a number of distinct catalytic activities. It has been shown for the yeast homolog GDB1 that mutations in this region disrupt the enzymes Amylo-alpha-1,6-glucosidase (EC:3.2.1.33).	6.56875e-156
NZ_CP021983.1|WP_080813407.1|2293250_2294243_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	9.37467e-107
NZ_CP021983.1|WP_088429768.1|2303193_2303997_+|3-oxoacyl-ACP-reductase	gnl|CDD|187616	cd05358, GlcDH_SDR_c, glucose 1 dehydrogenase (GlcDH), classical (c) SDRs. GlcDH, is a tetrameric member of the SDR family, it catalyzes the NAD(P)-dependent oxidation of beta-D-glucose to D-glucono-delta-lactone. GlcDH has a typical NAD-binding site glycine-rich pattern as well as the canonical active site tetrad (YXXXK motif plus upstream Ser and Asn). SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	4.62261e-107
NZ_CP021983.1|WP_080813425.1|2282033_2283728_+|RAMP-superfamily-protein	gnl|CDD|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	0.00060144
NZ_CP021983.1|WP_088429766.1|2301926_2303111_+|transaldolase	gnl|CDD|183426	PRK12309, PRK12309, transaldolase.	0
NZ_CP021983.1|WP_088429758.1|2285611_2285920_-|GIY-YIG-nuclease-family-protein	gnl|CDD|198403	cd10456, GIY-YIG_UPF0213, The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1. This family contains a group of uncharacterized proteins found mainly in bacteria and several in dsDNA viruses. Although their function roles have not been recognized, these proteins show significant sequence similarities with the N-terminal GIY-YIG endonuclease domain of structure-specific endonuclease subunit SLX1, which binds another structure-specific endonuclease subunit SLX4 to form an active heterodimeric SLX1-SLX4 complex. This complex functions as a 5' flap endonuclease in yeast, and has also been identified as a Holliday junction resolvase in human.	2.25881e-33
NZ_CP021983.1|WP_080813417.1|2286649_2287012_+|hypothetical-protein	gnl|CDD|375906	pfam18480, DUF5615, Domain of unknown function (DUF5615). This is a domain of unknown function found in potential toxin-antitoxin system component.	5.047e-10
NZ_CP021983.1|WP_088431631.1|2297065_2299498_+|endonuclease-MutS2	gnl|CDD|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	0
NZ_CP021983.1|WP_080813413.1|2288542_2288995_-|DUF3368-domain-containing-protein	gnl|CDD|225269	COG2405, COG2405, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	2.23493e-32

Protein sequences

>NZ_CP021983.1|WP_088429762.1|2289695_2290115_-|hypothetical-protein
MSRQKRNSTALEQAERRLESLRSIARDLDLGRGLSVHNFAAILDDLATKLAAYNTALSNIDKMADDIRMAEKAARAMSEQMLMGVGSHYGRTSQEYEMAGGSRRKGHPRARVTANVPAPVVVPTTEPSQNGASATPVSV
>NZ_CP021983.1|WP_080813411.1|2288991_2289210_-|hypothetical-protein
MAQLTIDLPASISTDEAKLFLAAKLYEVGKLSLGKAAKLAGYSKSSFIELISKMDVPVVNYPADDLEQEIAL
>NZ_CP021983.1|WP_080813413.1|2288542_2288995_-|DUF3368-domain-containing-protein
MNAAVTNSTCLIGLERIQQLDMLPQVFTPITISPAVQSEVGISAPWLTIQAPQNRGIVRSLQTQIDEGEAATIALAMELGDVFVILDDLSARRIAQQLQLKVIGTVGMLLRAKQQGIISEVKPILDALTTANFRISEAIVRRAIQLADEE
>NZ_CP021983.1|WP_088429760.1|2287035_2288472_+|hypothetical-protein
MQTLIITVGTRQVGWRCADGTVCCFGADGDRNQHPRHTDRLYAELGIQRGCQDGYPWSVQDLGQRYYHRCRHDLDGTFDPVELLLDHEIIEAQYSQGLTDVVLWGTRQPDTTDASYRSRDTHWLAQLMAGKIRQTWPELTVAVFEPVVAATDSTAIRHALEDFLVQHTQGVEEVTLLIQTKGALPAIAHSLDICAAALVRQYPVLQVVPIEPVPLYSGDSQSANRSQHHQVISIGEYFWPIERLRIVAAWQQGNFSEAALWLMAHQDRHRLLYRLAQQLSLAANWQIEALFQPQGLGQWLQAGSLHQVVPATQIEIWRTQVEAIRHSPPAQTWECSFLVYLLLRQGNYTDAFMRFAQTLERLLYLRSQADQWFHADELQGRHPGFKQLIDRWFQSQGTPLPGPHYDQVDRIRNTRNQVVHQAKAMTLDDLCRLWPSTASTTAEALHGAMEHMLHQMYASSSGPSLLHALYDWGLSQLI
>NZ_CP021983.1|WP_080813417.1|2286649_2287012_+|hypothetical-protein
MTLKYLLDENVDSVYQVQIQRQEPEVIVFRIGMPGTPSIQSSDSDILCWCEEHSFILLTNNRKSMPVHLADHLAQGRHVPGIFILNNELSLGQQLEELILIAMASEETDFQDRITYLPIV
>NZ_CP021983.1|WP_080813419.1|2286321_2286645_+|DUF433-domain-containing-protein
MQLEDYFDFLAPDDIRLKGTRVGIETILYDFIHRCRTPEAIAQSYPSLSLEQVYATILYYLHNQEAVSAYLADWMEWSHQRREEQRQNPPPQVLKLRQLKAEKAASQ
>NZ_CP021983.1|WP_088429758.1|2285611_2285920_-|GIY-YIG-nuclease-family-protein
MPYTYILECADGSYYTGSTWNMARRLWEHQEGLGANYTAKRLPVRLVYCEECDRIDTAFQREKQIQGWSRKKKLALIASDMNQLHVLAECQNASHHENLHAD
>NZ_CP021983.1|WP_088429756.1|2283864_2285352_+|hypothetical-protein
MTTWILTIGSSDVLLKSDRNWNSLERQAQAKTRDLPHFRPSIVKMPNGADFFAFPVRALGIVYSSQLETYSSDLCLPRLETLCGQFRTSYPEHIIILLTDQAHLQPAARRKTHHAYWQDTCELKPILEFYLNQKFPDVSQDYLIVRPEPQGETIEVLGLDHWDSTLSLIQALMADIDDKSHKTIYVSHQGGIPALSSAVQFVTLTKFADKVQFLVSNEFQENSSELISSSTYLRGIRLQEAKRLLLRHDYVGVQELLRHGLLTSDDPLGSKIDSLLNSAILWNQAQFKQFSESLPLELQERTQEWWWAGYESAYLAMIRLEQGNTVEALFHSFRAAEGMLSNWAKWYYPDDIKEDKKGAPIVFLREDSHLPDYLKSKLAEKREKNKEANFMLYSQELFNLFQAVHPDASENENVKVIWKGAKGVRNQQFHRLLGLNEKEVFRAWGCKENRKAWEDRLLNCLNFIAGQDFKSLKDSSLMSRVQAELWGALNSVNLP
>NZ_CP021983.1|WP_080813425.1|2282033_2283728_+|RAMP-superfamily-protein
MAQIPDMAKKVPMMFRAQVEGRCQLQRVYTDRNKSNEAQDSERWVSEWVEKAYPSPPVFDLTVQTRSYQLNWRFVTNGGQDDGIIRPVIGSFGWPFYPGSSMKGVFRQACNKDQAERYCGKELSGKDWQPGILRFHGGYPTNTQWTDRLVDIIHPQQERQVQREKTTSAFAQVSLYRPELQFGISSTELLDDTEWDTIWQIWERGLSSGLGCRVSAGYGQVADHAGQTLFKCRLKGQGQAPKLLDVDETGEFRPNIFRAAIRGHALRLFGGLTDATNAERLVNELFGSVQGSGDVGLLAMSFQPCREIIGSYGRGRWEQPTYEVEGDLYWMLNRPLADPNQRKALSNLIKALMHFAMVFGGFGKSWRRADHRIFYPDYAEQDAKPLIGCHWQWSEQSLTRNYKVRKLENIATFLQAIRKVARTWVQLQKANSRQWAKTWREAWHPQNVQVWGRVAREAEDSRAVEWLHGPYRPAMPTANILEGTIKQTSVTGKLNRIGRLWHRMYPIVRLVRNPEDPDGKPIAKMRSRPEYLELLTLFPNDSPEFLDFLDFLETQQTMFQKLWP
>NZ_CP021983.1|WP_080813426.1|2281597_2282050_+|hypothetical-protein
MAWNSYGLDREAQQLVLSARRRDEALPKAERSKKASLNQGHKMRMAIPYGLERFWGEHLRLQEKERNKSIYWKETWDAFVRVMDIAGIEIPNDDVSYSDTSGIQSMSERLWELDLKKQRVALAVLTQLCDALVWWTQRYKGGAKANGSNP
>NZ_CP021983.1|WP_080813407.1|2293250_2294243_+|CRISPR-associated-endonuclease-Cas1
MSTLYVAQQGCYVKLQQEQLLIKHNDAICQRVQLPLVDQILVFGHCQLTTQALRACLQRQVSVLYLSRMGQCYGRLLPMIQGYRQLARYQQDLSEVQRLRVAKILVKAKLWNSRVLLQRQGRTRPTPGIAQAVGQLAILIRQVNEARDNAALMGIEGAGAAAYFTALGDCFVQPGFTFTERNRRPPRDPVNAMLSFGYQVLWNHLYSLIEAQNLDPYEACLHQGSRKHAALVSDLLEPFRAPLVDSLVLYLVNRKVMDPEADFEPQKGGCYLNDSGRRKYLQAFVVRMETEITSSSTLPRPRWDLLMAQVQEYKRFVYEPQTLFKPYLIR
>NZ_CP021983.1|WP_080813406.1|2294247_2294526_+|CRISPR-associated-endonuclease-Cas2
MLLYIVAYDIPSNRRRKKISDLLEGYGRRVQYSVFELMLSPAKYAELRRRLRRYVQMEEDSVRFYPVSKHTLDQVEIWGGVPLTQPPGSIIV
>NZ_CP021983.1|WP_088431631.1|2297065_2299498_+|endonuclease-MutS2
MIQQETLDLLEWPRLCQQVSTFAATKLGAIAAQQLVIPTHQGDSERLLAQTQEAYRLDELPPGLKFTGIHDIGDALDRAGCQGILQGDELLAIATTLNGARQLRRFIDSQEEVPVLSQLVSELRTYPELEQTIHHCIDERGRVADRASEKLTGIREKLNHCRDQIYQKLQRILQRQGQAIQQPVITQRGDRFVLAVKAPQKDAIPGIVHDSSTSGATLYVEPHSVVDLGNRLRQLQRQEQAEDDAVRRRLSHQVAAVQPDLEQLLAIVTSLDLATARARYSRWLAANLPRFTATNEQTTLRQLRHPLLVWQQQHEEGPEVVPIDVIIRPQLRVIAITGPNTGGKTVTLKTLGLAALMAKAGLFLPAREPVELPWFSHILADIGDEQSIEQSLSTFSGHIKRISRILAAIQEPGDRAKLDGEAASEEEATAAAPANALVLLDEVGAGTDPSEGSALATALLQSLADQAQLTVATTHYGELKALKYQDDRFENASVEFDEVSLSPTYRLLWGIPGRSNALTIARRLGLATQVIEQAEATLGTGSHQDVNQIIAGLEAQRQRQEDKAAEAAQLVAQAERLHQEVTDKARFLRQREQSLQQQQTQAIQAAVTQARAEIAKVIRRLQQGQATAQEAQQATDAVNKIAQQHQPAPAAPAKAKPGFRPQEGDRVRLPSLGQTAEVLSPADEDGKLTVRFGLMKTTVSLADVESLQGEKVEMPSKPKPQTTVPAAPAAPAVRTSRNTFDLRGLRVSEAEAVLDDALARAQGPIWIIHGHGTGKLRAGVQEYLKHHPQVQRFEAAEQADGGTGVTVAHL
>NZ_CP021983.1|WP_088429764.1|2299505_2300951_-|deoxyribodipyrimidine-photolyase
MAEQLLFWHRRDLRLADNLGLAAAYQRSPKVVGVFCLDPAILQRDDVAPARVHYMLGCLQELQHRYGEAGGQLLILQGRPQQQIPALAAALGAAAVYWHRDVEPYSRQRDQAVAEALKEKGIEMCTTFWDQLLQSPGQVLTGGGTPYTVYTPFWRKWVQLPKAEPVPAPESFEGLSDREQTALEQGGTVALPSLQDLGFEWSSPLPLAAGEWAAQRRLEEFCREDRAIAQYGEARNLPCEDGTSRLSAALKFGAIGIRTVWAMAEAAYSRCRSDETRQNIRAWQQELAWREFYQHVMYFFPELAEGPYRPQWQYFPWVNDKQQFQAWCQGRTGYPIVDAAMRQLNQTGWMHNRCRMIVASFLTKDLIIDWRWGEKYFMQRLVDGDLAANNGGWQWSASSGMDPKPLRIFNPASQAKKFDPEAEYIRQWLPELRHLDTAPLVTGQIPEEDCDRNGYPRPIVDHKRQQAIFKDKYKAEKAATT
>NZ_CP021983.1|WP_088429766.1|2301926_2303111_+|transaldolase
MASSLLEQLRQMTTVVADTGDIQAIEQFTPQDATTNPSLITAAAQMPQYQEIVDETLLKAKQDAGSAMSDKAIANLAFKRLAVAFGLKILQIIPGRVSTEVDARLSYDTEATLATARDLIAQYEQAGVSRERVLIKIASTWEGIQAATVLEQEGIHCNLTLLFGLHQAIACAQAGVTLISPFVGRILDWYKQETGQEYPPAEDPGVLSVTQIYNYYKKFDHTTEVMGASFRNIGEICELAGCDLLTISPKLLAQLDSIQEPLVRRLDPEKAKTMAIDPISMDEAAFRQMHRQDRMASEKLEEGINGFSKALETLERLLVERLCARMAGEKMVDHAAQDLFKACDLDGDGFITREEWLGTDAVFDALDLDHDGKITAEEINAGLGVAVKPAMAVA
>NZ_CP021983.1|WP_088429768.1|2303193_2303997_+|3-oxoacyl-ACP-reductase
MRLDGKVALVTGSSQGIGQVIAIRLAEAGAKVVINYRSHPEGAAETVAKIRAMGGECHGAEGYCDDDHAFSIGADLSILADIHRLVGESIDHYGQLDILVNNAGIEKHAPFWEVTEKAFDAVINVNLKGVFFTTQAVVKHLMATERSGKIINISSVHEDLPFPNFAPYCASKGGLKMLTRDLAVELAPYGITVNNVAPGAIETPINSELLNNQAKLNALLKNIPLGRLGHPQDVAGLVEFLASDDANYITGSTFFVDGGLTWNYQEQ
>NZ_CP021983.1|WP_088429770.1|2304406_2306092_+|alpha-glucosidase
MSSSSHAMPQPWWEEGVIYQIYPLTFADGNGDGTGDLRGIIARLDYLNDGDPDSETCLGIDAIWLSPINQSPMIDNGYDVVDYTDICPIFGTLADFDELLDQAHQRGIKIVMDLVVNHTSNQHSWFLESASSRDHPKADWYLWQDAWEGRDLPNNWQSYFGGTGWTYAEERGQFYFHTFNENQPDLNWQNPEVRAAIYDIIRFWLDRGVDGFRLDASSAYSQDPYFRDNPLKYGASDKNAYNNYHHLYDRNLPENHQIIKEIRAILEEYGDRLLIGETFIDNRLYDSIVFYGVNNDELHFPLTFEFPFSPWYPGYLQRQIEKTEKVTPVGAWPTYFLDNHDIPRHLSRWIECSLCVDSVAIAKAAATLLLTVRGTPILYYGQELGMVDNTEIPANKLQDRAVVKSGTGETPPPRDGARTPMQWDDFPQAGFSFGRDVDPWLPVHTNYHQLNVQAALQDPDSILTFYRQLIQVRRRSGALRRGQWRPLIHYPHEHLAYVRETEAETVLVLINFSYEKPLELDVLVNREAWTVLLSTTYKTGKLIDLPDTLQPFEVSIVQKLA
>NZ_CP021983.1|WP_088429772.1|2306241_2308269_+|glycogen-debranching-protein
MTVPLGRDICGDLPHAERREWLVTNGIGGYGCGTIAGLLSRHYHGLLVAALKPPLQRTLLLAKLDEQVIYGGQVYALGCNRWADGAVIPQGYRLIERFCLEGTVPVWTFAIADGLLEKRVWMEQGANTTYVRYTLVRASQPLTLSLQALVNYRDHHGNPQGPGWQMQGRPRPQGIEIRAFEGAVPFYLLAAGAEISPAHSWYRHYALAVEQYRGIYPYDDHLHGATVTVDLAVGQSLTLVASTGPDADLNGEAALRRQRLHEQGLLQQWHAAAGQDHPAWVHQLVLAADQFVVGRTVAGTPGKTVIAGYPWFGDWGRDTMIALPGLAIATGRPAIARPILRTFAQYLDQGMLPNLFPEAGESPGYNTVDAILWYFEALRAYYQASQDQALLAELFPALAEVIEWHQRGSRYQIHLDSDGLIYAGEPGVQLTWMDAKVDDWVVTPRIGKPIEISALWYNALVAMAQFAPVLGKSATPYQQLAEQTRQGFQRFWPGNRGYCYDVLDGPEGDDTSLRPNQIVAVALPASELLGPSLLSPVQQRAVVDSVAQHLVTSYGLRSLAADAPQYQGHYGGDRWQRDGAYHQGPVWGWLIGPFVQAHLKVYGDSSLARRFLAPLADHLSDGCIGSLSEIFDGDPPHRPRGAFAQAWTVAEVLRAYRLTVEAPREYQATTGLDMT
>NZ_CP021983.1|WP_080814380.1|2308274_2309138_-|inositol-monophosphatase-family-protein
MPSPTPRQILDTLLPYLKTAGAYARQIQPRIAAQPAKAAGSDNFFAAALSDADLSVQTFVEVALLAHFPELRFYGEEHAQTYNTKYFRAIDLGPQDDYLITLDPIDGTQFYLDGHDNYQIILTVLNQDEFEAVLAISPSQHCYYYTVRGQGTHRGHWQDTMADCRPLMVQPKTPAVCLGFALTALIDPLKDRYQVFHTGSSYSKQRQIPNFNGLLSGDLAGAVLERSQFIDGAALAFMAQEMGYWVTTWEGQPPPPLHQCRDMRRPGLVIGATAEVHRDLLAAVRTI
>NZ_CP021983.1|WP_088429774.1|2309246_2309933_-|KR-domain-containing-protein
MAQHILITGVSRGLGRAMTEEFISLGHTIWGCARQAEPVTALQNHYGPPHDFAVVDVANQDQVKAWGQSLLERHGPPDILINNAGVINALAPLWQVPPAEFDRVIDVNIKGVANVLRQFVPAMVQRGRGIIVNLSSGWGRSTSPQVAPYCTSKWAIEGMTRALAQELPATMAAVPLNPGIIHTDMLEVCYGDEAASFTALQQWKKQVVPFILQLSPKDNGRPLTVPGG

Crispr_ID: NZ_CP021983_16

• CRISPR_ID: NZ_CP021983_16
• CRISPR_location: 2294711-2296526
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 24 spacers
• Cas_protein_info: cas2,cas1,csx1

Consensus repeat of NZ_CP021983_16

Consensus_repeat	Method
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	PILER-CR
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	CRISPRCasFinder
CCCCACTCGTTGGGGAAACTAATTGAATGGAAA	CRT
CCCACTCGTTGGGGAAACTAATTGAATGGAAAC	PILER-CR

spacers of NZ_CP021983_16

>16.1|2294747|39|NZ_CP021983|PILER-CR,CRISPRCasFinder
TATCGAGTGAGTCACCGTCTCGTCATTTGGGTCGATTAT
>16.2|2294822|42|NZ_CP021983|PILER-CR,CRISPRCasFinder
TACATCCGAACTTAAGCCCAGGGGGTACACCGCCGCCAGAGG
>16.3|2294900|42|NZ_CP021983|PILER-CR,CRISPRCasFinder
TGAATTACTGTCGCTCATTATTGGGAGAGCGGTAGTCGGACT
>16.4|2294978|40|NZ_CP021983|PILER-CR,CRISPRCasFinder
GACTCGAGATTCAAGCCGCCGGCCCGGACGAAGGTGTCCA
>16.5|2295054|39|NZ_CP021983|CRISPRCasFinder
CTTGTGTAACGTCACAATCAAACCAACAATTATTTACAG
>16.6|2295129|47|NZ_CP021983|CRISPRCasFinder
ATGGTTCTTCTGCGGCGAATCAATCAGTAGATGAATCCCTTATAGAC
>16.7|2295212|39|NZ_CP021983|CRISPRCasFinder
GCATAATCCCTTAGCACGACCTTGGCGGCTCCCCGTTGA
>16.8|2295287|35|NZ_CP021983|CRISPRCasFinder
TGAATTGTCAGTGCCATCATTATCACTATCAACGA
>16.9|2295358|36|NZ_CP021983|CRISPRCasFinder
CCCCCGGATGGCGTCTCGTGAGGCCGAAATTAACAA
>16.10|2295430|43|NZ_CP021983|CRISPRCasFinder
CTAATACTTCCAAAACGTTTAAGGAAATTTCTGGACGATCCCA
>16.11|2295509|35|NZ_CP021983|CRISPRCasFinder
TCAAATGAGGCTGAGGGATTATGGGAGAGTTTAAG
>16.12|2295580|35|NZ_CP021983|CRISPRCasFinder
ATATAAATCATCTTGAATTTTTACGTATGGTCGCA
>16.13|2295651|35|NZ_CP021983|CRISPRCasFinder
CACTCATCAATAATTTCAATGAGTATGATTTTAGG
>16.14|2295722|36|NZ_CP021983|CRISPRCasFinder
TTAGTGATTTCAAAGGAAGCTCCATTAGCAAAAGTC
>16.15|2295794|34|NZ_CP021983|CRISPRCasFinder
TCCGTATTTCTGAAATATTCAGTATTCAGCCAAC
>16.16|2295864|39|NZ_CP021983|CRISPRCasFinder
GCAAAAGATTTAATAAAACTATTGAGGCGGCTATGACTT
>16.17|2295939|41|NZ_CP021983|CRISPRCasFinder
TAATTCCATTGATTTATTCCCCTCTAGTCTTTGGCTGACAA
>16.18|2296016|38|NZ_CP021983|CRISPRCasFinder
GTTCTTCAAGTGATCTTCATCTATCTTCAGAACAGAAG
>16.19|2296090|36|NZ_CP021983|CRISPRCasFinder
TCTCCGATGAAGTTCCAACACCTGTTGTTAGAACAC
>16.20|2296162|38|NZ_CP021983|CRISPRCasFinder
GTAAAATGGCTCCTGCTCGATTAGCCACTGACAGCCAA
>16.21|2296236|38|NZ_CP021983|CRISPRCasFinder
CCGTAGGAGTAGTAACGATAATCTCCTTGATCCCCTTG
>16.22|2296310|39|NZ_CP021983|CRISPRCasFinder
GGGTGAACGACCGTCCATCGGACGGGACCACAGTCTCCG
>16.23|2296385|34|NZ_CP021983|CRISPRCasFinder
ATTTTACTAAAGCAAAAAGCTCTCCGGAGATAGC
>16.24|2296455|36|NZ_CP021983|CRISPRCasFinder
TTCATATTCCCCAGTGGACAAGGATAGAGTTCGCCA
>16.25|2294746|43|NZ_CP021983|CRT
CTATCGAGTGAGTCACCGTCTCGTCATTTGGGTCGATTATGTC
>16.26|2294821|46|NZ_CP021983|CRT
CTACATCCGAACTTAAGCCCAGGGGGTACACCGCCGCCAGAGGGTC
>16.27|2294899|46|NZ_CP021983|CRT
CTGAATTACTGTCGCTCATTATTGGGAGAGCGGTAGTCGGACTGTC
>16.28|2294977|44|NZ_CP021983|CRT
CGACTCGAGATTCAAGCCGCCGGCCCGGACGAAGGTGTCCAGTC
>16.29|2295053|43|NZ_CP021983|CRT
CCTTGTGTAACGTCACAATCAAACCAACAATTATTTACAGGTC
>16.30|2295128|51|NZ_CP021983|CRT
CATGGTTCTTCTGCGGCGAATCAATCAGTAGATGAATCCCTTATAGACGTC
>16.31|2295211|43|NZ_CP021983|CRT
CGCATAATCCCTTAGCACGACCTTGGCGGCTCCCCGTTGAGTC
>16.32|2295286|39|NZ_CP021983|CRT
CTGAATTGTCAGTGCCATCATTATCACTATCAACGACGT
>16.33|2295357|40|NZ_CP021983|CRT
CCCCCCGGATGGCGTCTCGTGAGGCCGAAATTAACAAGTC
>16.34|2295429|47|NZ_CP021983|CRT
CCTAATACTTCCAAAACGTTTAAGGAAATTTCTGGACGATCCCATGT
>16.35|2295508|38|NZ_CP021983|CRT
CTCAAATGAGGCTGAGGGATTATGGGAGAGTTTAAGGT
>16.36|2295578|39|NZ_CP021983|CRT
ACATATAAATCATCTTGAATTTTTACGTATGGTCGCAGT
>16.37|2295649|39|NZ_CP021983|CRT
ACCACTCATCAATAATTTCAATGAGTATGATTTTAGGGT
>16.38|2295720|40|NZ_CP021983|CRT
ACTTAGTGATTTCAAAGGAAGCTCCATTAGCAAAAGTCGT
>16.39|2295792|38|NZ_CP021983|CRT
ACTCCGTATTTCTGAAATATTCAGTATTCAGCCAACGT
>16.40|2295862|43|NZ_CP021983|CRT
ACGCAAAAGATTTAATAAAACTATTGAGGCGGCTATGACTTGT
>16.41|2295937|45|NZ_CP021983|CRT
ACTAATTCCATTGATTTATTCCCCTCTAGTCTTTGGCTGACAAGT
>16.42|2296014|42|NZ_CP021983|CRT
ACGTTCTTCAAGTGATCTTCATCTATCTTCAGAACAGAAGGT
>16.43|2296088|40|NZ_CP021983|CRT
ACTCTCCGATGAAGTTCCAACACCTGTTGTTAGAACACGT
>16.44|2296160|42|NZ_CP021983|CRT
ACGTAAAATGGCTCCTGCTCGATTAGCCACTGACAGCCAAGT
>16.45|2296234|42|NZ_CP021983|CRT
ACCCGTAGGAGTAGTAACGATAATCTCCTTGATCCCCTTGGT
>16.46|2296308|43|NZ_CP021983|CRT
ACGGGTGAACGACCGTCCATCGGACGGGACCACAGTCTCCGGT
>16.47|2296383|38|NZ_CP021983|CRT
ACATTTTACTAAAGCAAAAAGCTCTCCGGAGATAGCCG
>16.48|2296453|40|NZ_CP021983|CRT
ACTTCATATTCCCCAGTGGACAAGGATAGAGTTCGCCAGT
>16.49|2295212|42|NZ_CP021983|PILER-CR
GCATAATCCCTTAGCACGACCTTGGCGGCTCCCCGTTGAGTC
>16.50|2295287|38|NZ_CP021983|PILER-CR
TGAATTGTCAGTGCCATCATTATCACTATCAACGACGT
>16.51|2295358|39|NZ_CP021983|PILER-CR
CCCCCGGATGGCGTCTCGTGAGGCCGAAATTAACAAGTC
>16.52|2295430|47|NZ_CP021983|PILER-CR
CTAATACTTCCAAAACGTTTAAGGAAATTTCTGGACGATCCCATGTC
>16.53|2295510|38|NZ_CP021983|PILER-CR
TCAAATGAGGCTGAGGGATTATGGGAGAGTTTAAGGTC
>16.54|2295581|38|NZ_CP021983|PILER-CR
ATATAAATCATCTTGAATTTTTACGTATGGTCGCAGTC
>16.55|2295652|38|NZ_CP021983|PILER-CR
CACTCATCAATAATTTCAATGAGTATGATTTTAGGGTC
>16.56|2295723|39|NZ_CP021983|PILER-CR
TTAGTGATTTCAAAGGAAGCTCCATTAGCAAAAGTCGTC
>16.57|2295795|37|NZ_CP021983|PILER-CR
TCCGTATTTCTGAAATATTCAGTATTCAGCCAACGTC
>16.58|2295865|42|NZ_CP021983|PILER-CR
GCAAAAGATTTAATAAAACTATTGAGGCGGCTATGACTTGTC
>16.59|2295940|44|NZ_CP021983|PILER-CR
TAATTCCATTGATTTATTCCCCTCTAGTCTTTGGCTGACAAGTC
>16.60|2296017|41|NZ_CP021983|PILER-CR
GTTCTTCAAGTGATCTTCATCTATCTTCAGAACAGAAGGTC
>16.61|2296091|39|NZ_CP021983|PILER-CR
TCTCCGATGAAGTTCCAACACCTGTTGTTAGAACACGTC
>16.62|2296163|41|NZ_CP021983|PILER-CR
GTAAAATGGCTCCTGCTCGATTAGCCACTGACAGCCAAGTC
>16.63|2296237|41|NZ_CP021983|PILER-CR
CCGTAGGAGTAGTAACGATAATCTCCTTGATCCCCTTGGTC
>16.64|2296311|42|NZ_CP021983|PILER-CR
GGGTGAACGACCGTCCATCGGACGGGACCACAGTCTCCGGTC
>16.65|2296386|37|NZ_CP021983|PILER-CR
ATTTTACTAAAGCAAAAAGCTCTCCGGAGATAGCCGT
>16.66|2296456|39|NZ_CP021983|PILER-CR
TTCATATTCCCCAGTGGACAAGGATAGAGTTCGCCAGTC

CRISPR arrays and Neighbor proteins around NZ_CP021983_16

CRISPR arrays

The CRISPR arrays of NZ_CP021983_16

>merge|NZ_CP021983|16|2294711-2296526|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACTATCGAGTGAGTCACCGTCTCGTCATTTGGGTCGATTATGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACTACATCCGAACTTAAGCCCAGGGGGTACACCGCCGCCAGAGGGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACTGAATTACTGTCGCTCATTATTGGGAGAGCGGTAGTCGGACTGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACGACTCGAGATTCAAGCCGCCGGCCCGGACGAAGGTGTCCAGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACCTTGTGTAACGTCACAATCAAACCAACAATTATTTACAGGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACATGGTTCTTCTGCGGCGAATCAATCAGTAGATGAATCCCTTATAGACGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACGCATAATCCCTTAGCACGACCTTGGCGGCTCCCCGTTGAGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACTGAATTGTCAGTGCCATCATTATCACTATCAACGACGTCCCACTCGTTGGGGAAACTAATTGAATGGAAACCCCCCGGATGGCGTCTCGTGAGGCCGAAATTAACAAGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACCTAATACTTCCAAAACGTTTAAGGAAATTTCTGGACGATCCCATGTCCCCACTCGTTGGGGAACTAATTGAATGGAAACTCAAATGAGGCTGAGGGATTATGGGAGAGTTTAAGGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACATATAAATCATCTTGAATTTTTACGTATGGTCGCAGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACCACTCATCAATAATTTCAATGAGTATGATTTTAGGGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACTTAGTGATTTCAAAGGAAGCTCCATTAGCAAAAGTCGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACTCCGTATTTCTGAAATATTCAGTATTCAGCCAACGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACGCAAAAGATTTAATAAAACTATTGAGGCGGCTATGACTTGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACTAATTCCATTGATTTATTCCCCTCTAGTCTTTGGCTGACAAGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACGTTCTTCAAGTGATCTTCATCTATCTTCAGAACAGAAGGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACTCTCCGATGAAGTTCCAACACCTGTTGTTAGAACACGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACGTAAAATGGCTCCTGCTCGATTAGCCACTGACAGCCAAGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACCCGTAGGAGTAGTAACGATAATCTCCTTGATCCCCTTGGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACGGGTGAACGACCGTCCATCGGACGGGACCACAGTCTCCGGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACATTTTACTAAAGCAAAAAGCTCTCCGGAGATAGCCGTCCCACTCGTTGGGGAAACTAATTGAATGGAAACTTCATATTCCCCAGTGGACAAGGATAGAGTTCGCCAGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC

>NZ_CP021983|16|7|2294711-2295053|PILER-CR
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	TATCGAGTGAGTCACCGTCTCGTCATTTGGGTCGATTAT
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	TACATCCGAACTTAAGCCCAGGGGGTACACCGCCGCCAGAGG
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	TGAATTACTGTCGCTCATTATTGGGAGAGCGGTAGTCGGACT
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	GACTCGAGATTCAAGCCGCCGGCCCGGACGAAGGTGTCCA
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACCTTGTGTAACGTCACAATCAAACCAACAATTATTTACAGGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACATGGTTCTTCTGCGGCGAATCAATCAGTAGATGAATCCCTTATAGACGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	GCATAATCCCTTAGCACGACCTTGGCGGCTCCCCGTTGAGTC
CCCACTCGTTGGGGAAACTAATTGAATGGAAAC	TGAATTGTCAGTGCCATCATTATCACTATCAACGACGT
CCCACTCGTTGGGGAAACTAATTGAATGGAAAC	CCCCCGGATGGCGTCTCGTGAGGCCGAAATTAACAAGTC
CCCACTCGTTGGGGAAACTAATTGAATGGAAAC	CTAATACTTCCAAAACGTTTAAGGAAATTTCTGGACGATCCCATGTC
CCCACTCGTTGGGGAACTAATTGAATGGAAACT	CAAATGAGGCTGAGGGATTATGGGAGAGTTTAAGGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACA	TATAAATCATCTTGAATTTTTACGTATGGTCGCAGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACC	ACTCATCAATAATTTCAATGAGTATGATTTTAGGGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACT	TAGTGATTTCAAAGGAAGCTCCATTAGCAAAAGTCGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACT	CCGTATTTCTGAAATATTCAGTATTCAGCCAACGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACG	CAAAAGATTTAATAAAACTATTGAGGCGGCTATGACTTGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACT	AATTCCATTGATTTATTCCCCTCTAGTCTTTGGCTGACAAGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACG	TTCTTCAAGTGATCTTCATCTATCTTCAGAACAGAAGGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACT	CTCCGATGAAGTTCCAACACCTGTTGTTAGAACACGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACG	TAAAATGGCTCCTGCTCGATTAGCCACTGACAGCCAAGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACC	CGTAGGAGTAGTAACGATAATCTCCTTGATCCCCTTGGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACG	GGTGAACGACCGTCCATCGGACGGGACCACAGTCTCCGGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACA	TTTTACTAAAGCAAAAAGCTCTCCGGAGATAGCCGTC
CCACTCGTTGGGGAAACTAATTGAATGGAAACT	TCATATTCCCCAGTGGACAAGGATAGAGTTCGCCAGTCC


>NZ_CP021983|16|17|2294711-2296526|CRISPRCasFinder
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	TATCGAGTGAGTCACCGTCTCGTCATTTGGGTCGATTAT
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	TACATCCGAACTTAAGCCCAGGGGGTACACCGCCGCCAGAGG
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	TGAATTACTGTCGCTCATTATTGGGAGAGCGGTAGTCGGACT
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	GACTCGAGATTCAAGCCGCCGGCCCGGACGAAGGTGTCCA
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	CTTGTGTAACGTCACAATCAAACCAACAATTATTTACAG
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	ATGGTTCTTCTGCGGCGAATCAATCAGTAGATGAATCCCTTATAGAC
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	GCATAATCCCTTAGCACGACCTTGGCGGCTCCCCGTTGA
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	TGAATTGTCAGTGCCATCATTATCACTATCAACGA
CGTCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	CCCCCGGATGGCGTCTCGTGAGGCCGAAATTAACAA
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	CTAATACTTCCAAAACGTTTAAGGAAATTTCTGGACGATCCCA
TGTCCCCACTCGTTGGGGAACTAATTGAATGGAAAC	TCAAATGAGGCTGAGGGATTATGGGAGAGTTTAAG
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	ATATAAATCATCTTGAATTTTTACGTATGGTCGCA
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	CACTCATCAATAATTTCAATGAGTATGATTTTAGG
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	TTAGTGATTTCAAAGGAAGCTCCATTAGCAAAAGTC
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	TCCGTATTTCTGAAATATTCAGTATTCAGCCAAC
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	GCAAAAGATTTAATAAAACTATTGAGGCGGCTATGACTT
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	TAATTCCATTGATTTATTCCCCTCTAGTCTTTGGCTGACAA
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	GTTCTTCAAGTGATCTTCATCTATCTTCAGAACAGAAG
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	TCTCCGATGAAGTTCCAACACCTGTTGTTAGAACAC
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	GTAAAATGGCTCCTGCTCGATTAGCCACTGACAGCCAA
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	CCGTAGGAGTAGTAACGATAATCTCCTTGATCCCCTTG
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	GGGTGAACGACCGTCCATCGGACGGGACCACAGTCTCCG
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	ATTTTACTAAAGCAAAAAGCTCTCCGGAGATAGC
CGTCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	TTCATATTCCCCAGTGGACAAGGATAGAGTTCGCCA
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC

>NZ_CP021983|16|7|2294714-2296524|CRT
CCCACTCGTTGGGGAAACTAATTGAATGGAAA	CTATCGAGTGAGTCACCGTCTCGTCATTTGGGTCGATTATGTC
CCCACTCGTTGGGGAAACTAATTGAATGGAAA	CTACATCCGAACTTAAGCCCAGGGGGTACACCGCCGCCAGAGGGTC
CCCACTCGTTGGGGAAACTAATTGAATGGAAA	CTGAATTACTGTCGCTCATTATTGGGAGAGCGGTAGTCGGACTGTC
CCCACTCGTTGGGGAAACTAATTGAATGGAAA	CGACTCGAGATTCAAGCCGCCGGCCCGGACGAAGGTGTCCAGTC
CCCACTCGTTGGGGAAACTAATTGAATGGAAA	CCTTGTGTAACGTCACAATCAAACCAACAATTATTTACAGGTC
CCCACTCGTTGGGGAAACTAATTGAATGGAAA	CATGGTTCTTCTGCGGCGAATCAATCAGTAGATGAATCCCTTATAGACGTC
CCCACTCGTTGGGGAAACTAATTGAATGGAAA	CGCATAATCCCTTAGCACGACCTTGGCGGCTCCCCGTTGAGTC
CCCACTCGTTGGGGAAACTAATTGAATGGAAA	CTGAATTGTCAGTGCCATCATTATCACTATCAACGACGT
CCCACTCGTTGGGGAAACTAATTGAATGGAAA	CCCCCCGGATGGCGTCTCGTGAGGCCGAAATTAACAAGTC
CCCACTCGTTGGGGAAACTAATTGAATGGAAA	CCTAATACTTCCAAAACGTTTAAGGAAATTTCTGGACGATCCCATGT
CCCCACTCGTTGGGGAACTAATTGAATGGAAA	CTCAAATGAGGCTGAGGGATTATGGGAGAGTTTAAGGT
CCCCACTCGTTGGGGAAACTAATTGAATGGAA	ACATATAAATCATCTTGAATTTTTACGTATGGTCGCAGT
CCCCACTCGTTGGGGAAACTAATTGAATGGAA	ACCACTCATCAATAATTTCAATGAGTATGATTTTAGGGT
CCCCACTCGTTGGGGAAACTAATTGAATGGAA	ACTTAGTGATTTCAAAGGAAGCTCCATTAGCAAAAGTCGT
CCCCACTCGTTGGGGAAACTAATTGAATGGAA	ACTCCGTATTTCTGAAATATTCAGTATTCAGCCAACGT
CCCCACTCGTTGGGGAAACTAATTGAATGGAA	ACGCAAAAGATTTAATAAAACTATTGAGGCGGCTATGACTTGT
CCCCACTCGTTGGGGAAACTAATTGAATGGAA	ACTAATTCCATTGATTTATTCCCCTCTAGTCTTTGGCTGACAAGT
CCCCACTCGTTGGGGAAACTAATTGAATGGAA	ACGTTCTTCAAGTGATCTTCATCTATCTTCAGAACAGAAGGT
CCCCACTCGTTGGGGAAACTAATTGAATGGAA	ACTCTCCGATGAAGTTCCAACACCTGTTGTTAGAACACGT
CCCCACTCGTTGGGGAAACTAATTGAATGGAA	ACGTAAAATGGCTCCTGCTCGATTAGCCACTGACAGCCAAGT
CCCCACTCGTTGGGGAAACTAATTGAATGGAA	ACCCGTAGGAGTAGTAACGATAATCTCCTTGATCCCCTTGGT
CCCCACTCGTTGGGGAAACTAATTGAATGGAA	ACGGGTGAACGACCGTCCATCGGACGGGACCACAGTCTCCGGT
CCCCACTCGTTGGGGAAACTAATTGAATGGAA	ACATTTTACTAAAGCAAAAAGCTCTCCGGAGATAGCCG
TCCCACTCGTTGGGGAAACTAATTGAATGGAA	ACTTCATATTCCCCAGTGGACAAGGATAGAGTTCGCCAGT
CCCCACTCGTTGGGGAAACTAATTGAATGGAA

>NZ_CP021983|16|8|2295179-2296526|PILER-CR
	TATCGAGTGAGTCACCGTCTCGTCATTTGGGTCGATTAT
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	TACATCCGAACTTAAGCCCAGGGGGTACACCGCCGCCAGAGG
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	TGAATTACTGTCGCTCATTATTGGGAGAGCGGTAGTCGGACT
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	GACTCGAGATTCAAGCCGCCGGCCCGGACGAAGGTGTCCA
GTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACCTTGTGTAACGTCACAATCAAACCAACAATTATTTACAGGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAACATGGTTCTTCTGCGGCGAATCAATCAGTAGATGAATCCCTTATAGACGTCCCCACTCGTTGGGGAAACTAATTGAATGGAAAC	GCATAATCCCTTAGCACGACCTTGGCGGCTCCCCGTTGAGTC
CCCACTCGTTGGGGAAACTAATTGAATGGAAAC	TGAATTGTCAGTGCCATCATTATCACTATCAACGACGT
CCCACTCGTTGGGGAAACTAATTGAATGGAAAC	CCCCCGGATGGCGTCTCGTGAGGCCGAAATTAACAAGTC
CCCACTCGTTGGGGAAACTAATTGAATGGAAAC	CTAATACTTCCAAAACGTTTAAGGAAATTTCTGGACGATCCCATGTC
CCCACTCGTTGGGGAACTAATTGAATGGAAACT	CAAATGAGGCTGAGGGATTATGGGAGAGTTTAAGGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACA	TATAAATCATCTTGAATTTTTACGTATGGTCGCAGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACC	ACTCATCAATAATTTCAATGAGTATGATTTTAGGGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACT	TAGTGATTTCAAAGGAAGCTCCATTAGCAAAAGTCGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACT	CCGTATTTCTGAAATATTCAGTATTCAGCCAACGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACG	CAAAAGATTTAATAAAACTATTGAGGCGGCTATGACTTGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACT	AATTCCATTGATTTATTCCCCTCTAGTCTTTGGCTGACAAGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACG	TTCTTCAAGTGATCTTCATCTATCTTCAGAACAGAAGGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACT	CTCCGATGAAGTTCCAACACCTGTTGTTAGAACACGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACG	TAAAATGGCTCCTGCTCGATTAGCCACTGACAGCCAAGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACC	CGTAGGAGTAGTAACGATAATCTCCTTGATCCCCTTGGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACG	GGTGAACGACCGTCCATCGGACGGGACCACAGTCTCCGGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAACA	TTTTACTAAAGCAAAAAGCTCTCCGGAGATAGCCGTC
CCACTCGTTGGGGAAACTAATTGAATGGAAACT	TCATATTCCCCAGTGGACAAGGATAGAGTTCGCCAGTCC
CCACTCGTTGGGGAAACTAATTGAATGGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_088429766.1|2301926_2303111_+|transaldolase	unknown	unknown	gnl|CDD|183426
NZ_CP021983.1|WP_080810634.1|2315792_2319440_-|methionine-synthase	unknown	unknown	gnl|CDD|273959
NZ_CP021983.1|WP_088429774.1|2309246_2309933_-|KR-domain-containing-protein	unknown	unknown	gnl|CDD|235546
NZ_CP021983.1|WP_080813411.1|2288991_2289210_-|hypothetical-protein	unknown	unknown	gnl|CDD|377095
NZ_CP021983.1|WP_088429762.1|2289695_2290115_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088429770.1|2304406_2306092_+|alpha-glucosidase	unknown	unknown	gnl|CDD|200472
NZ_CP021983.1|WP_080813406.1|2294247_2294526_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NZ_CP021983.1|WP_080813413.1|2288542_2288995_-|DUF3368-domain-containing-protein	unknown	unknown	gnl|CDD|225269
NZ_CP021983.1|WP_080813419.1|2286321_2286645_+|DUF433-domain-containing-protein	unknown	unknown	gnl|CDD|377269
NZ_CP021983.1|WP_080814380.1|2308274_2309138_-|inositol-monophosphatase-family-protein	unknown	unknown	gnl|CDD|238815
NZ_CP021983.1|WP_088429772.1|2306241_2308269_+|glycogen-debranching-protein	unknown	unknown	gnl|CDD|283786
NZ_CP021983.1|WP_080813407.1|2293250_2294243_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|376633
NZ_CP021983.1|WP_088429760.1|2287035_2288472_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080813417.1|2286649_2287012_+|hypothetical-protein	unknown	unknown	gnl|CDD|375906
NZ_CP021983.1|WP_080810632.1|2310020_2315396_-|hypothetical-protein	unknown	unknown	gnl|CDD|226415
NZ_CP021983.1|WP_088429768.1|2303193_2303997_+|3-oxoacyl-ACP-reductase	unknown	unknown	gnl|CDD|187616
NZ_CP021983.1|WP_088429758.1|2285611_2285920_-|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl|CDD|198403
NZ_CP021983.1|WP_088431631.1|2297065_2299498_+|endonuclease-MutS2	unknown	unknown	gnl|CDD|234750
NZ_CP021983.1|WP_088429756.1|2283864_2285352_+|hypothetical-protein	csx1	mkCas0108_csx1_CAS-III	unknown
NZ_CP021983.1|WP_088429764.1|2299505_2300951_-|deoxyribodipyrimidine-photolyase	unknown	unknown	gnl|CDD|274644

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP021983.1|WP_080813406.1|2294247_2294526_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	1.9e-28	93.2	0.0
NZ_CP021983.1|WP_080813407.1|2293250_2294243_+|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	9.6e-85	279.1	0.0
NZ_CP021983.1|WP_088429756.1|2283864_2285352_+|hypothetical-protein	csx1	mkCas0108_csx1_CAS-III	1.3e-90	299.4	5.9

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_088429770.1|2304406_2306092_+|alpha-glucosidase	gnl|CDD|200472	cd11333, AmyAc_SI_OligoGlu_DGase, Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins. The sucrose isomerases (SIs) Isomaltulose synthase (EC 5.4.99.11) and Trehalose synthase (EC 5.4.99.16) catalyze the isomerization of sucrose and maltose to produce isomaltulose and trehalulose, respectively. Oligo-1,6-glucosidase (EC 3.2.1.10) hydrolyzes the alpha-1,6-glucosidic linkage of isomaltooligosaccharides, pannose, and dextran. Unlike alpha-1,4-glucosidases (EC 3.2.1.20), it fails to hydrolyze the alpha-1,4-glucosidic bonds of maltosaccharides. Dextran glucosidase (DGase, EC 3.2.1.70) hydrolyzes alpha-1,6-glucosidic linkages at the non-reducing end of panose, isomaltooligosaccharides and dextran to produce alpha-glucose.The common reaction chemistry of the alpha-amylase family enzymes is based on a two-step acid catalytic mechanism that requires two critical carboxylates: one acting as a general acid/base (Glu) and the other as a nucleophile (Asp). Both hydrolysis and transglycosylation proceed via the nucleophilic substitution reaction between the anomeric carbon, C1 and a nucleophile. Both enzymes contain the three catalytic residues (Asp, Glu and Asp) common to the alpha-amylase family as well as two histidine residues which are predicted to be critical to binding the glucose residue adjacent to the scissile bond in the substrates. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
NZ_CP021983.1|WP_080810634.1|2315792_2319440_-|methionine-synthase	gnl|CDD|273959	TIGR02082, Methionine_synthase, 5-methyltetrahydrofolate--homocysteine methyltransferase. This family represents 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13), one of at least three different enzymes able to convert homocysteine to methionine by transferring a methyl group on to the sulfur atom. It is also called the vitamin B12(or cobalamine)-dependent methionine synthase. Other methionine synthases include 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (MetE, EC 2.1.1.14, the cobalamin-independent methionine synthase) and betaine-homocysteine methyltransferase. [Amino acid biosynthesis, Aspartate family].	0
NZ_CP021983.1|WP_088429774.1|2309246_2309933_-|KR-domain-containing-protein	gnl|CDD|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	2.25803e-51
NZ_CP021983.1|WP_080813411.1|2288991_2289210_-|hypothetical-protein	gnl|CDD|377095	pfam03683, UPF0175, Uncharacterized protein family (UPF0175). This family contains small proteins of unknown function.	3.37825e-16
NZ_CP021983.1|WP_088429768.1|2303193_2303997_+|3-oxoacyl-ACP-reductase	gnl|CDD|187616	cd05358, GlcDH_SDR_c, glucose 1 dehydrogenase (GlcDH), classical (c) SDRs. GlcDH, is a tetrameric member of the SDR family, it catalyzes the NAD(P)-dependent oxidation of beta-D-glucose to D-glucono-delta-lactone. GlcDH has a typical NAD-binding site glycine-rich pattern as well as the canonical active site tetrad (YXXXK motif plus upstream Ser and Asn). SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	4.62261e-107
NZ_CP021983.1|WP_088429764.1|2299505_2300951_-|deoxyribodipyrimidine-photolyase	gnl|CDD|274644	TIGR03556, photolyase_8HDF, deoxyribodipyrimidine photo-lyase, 8-HDF type. This model describes a narrow clade of cyanobacterial deoxyribodipyrimidine photo-lyase. This group, in contrast to several closely related proteins, uses a chromophore that, in other lineages is modified further to become coenzyme F420. This chromophore is called 8-HDF in most articles on the DNA photolyase and FO in most literature on coenzyme F420. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP021983.1|WP_080813419.1|2286321_2286645_+|DUF433-domain-containing-protein	gnl|CDD|377269	pfam04255, DUF433, Protein of unknown function (DUF433).	6.9739e-06
NZ_CP021983.1|WP_080814380.1|2308274_2309138_-|inositol-monophosphatase-family-protein	gnl|CDD|238815	cd01637, IMPase_like, Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1,6-bisphosphate, inositol poly- and monophosphates, PAP and PAPS, sedoheptulose-1,7-bisphosphate and probably others.	1.27422e-27
NZ_CP021983.1|WP_088429772.1|2306241_2308269_+|glycogen-debranching-protein	gnl|CDD|283786	pfam06202, GDE_C, Amylo-alpha-1,6-glucosidase. This family includes human glycogen branching enzyme AGL. This enzyme contains a number of distinct catalytic activities. It has been shown for the yeast homolog GDB1 that mutations in this region disrupt the enzymes Amylo-alpha-1,6-glucosidase (EC:3.2.1.33).	6.56875e-156
NZ_CP021983.1|WP_080813407.1|2293250_2294243_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	9.37467e-107
NZ_CP021983.1|WP_080813413.1|2288542_2288995_-|DUF3368-domain-containing-protein	gnl|CDD|225269	COG2405, COG2405, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	2.23493e-32
NZ_CP021983.1|WP_080813417.1|2286649_2287012_+|hypothetical-protein	gnl|CDD|375906	pfam18480, DUF5615, Domain of unknown function (DUF5615). This is a domain of unknown function found in potential toxin-antitoxin system component.	5.047e-10
NZ_CP021983.1|WP_080810632.1|2310020_2315396_-|hypothetical-protein	gnl|CDD|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	0
NZ_CP021983.1|WP_088429758.1|2285611_2285920_-|GIY-YIG-nuclease-family-protein	gnl|CDD|198403	cd10456, GIY-YIG_UPF0213, The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1. This family contains a group of uncharacterized proteins found mainly in bacteria and several in dsDNA viruses. Although their function roles have not been recognized, these proteins show significant sequence similarities with the N-terminal GIY-YIG endonuclease domain of structure-specific endonuclease subunit SLX1, which binds another structure-specific endonuclease subunit SLX4 to form an active heterodimeric SLX1-SLX4 complex. This complex functions as a 5' flap endonuclease in yeast, and has also been identified as a Holliday junction resolvase in human.	2.25881e-33
NZ_CP021983.1|WP_088429766.1|2301926_2303111_+|transaldolase	gnl|CDD|183426	PRK12309, PRK12309, transaldolase.	0
NZ_CP021983.1|WP_088431631.1|2297065_2299498_+|endonuclease-MutS2	gnl|CDD|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	0
NZ_CP021983.1|WP_080813406.1|2294247_2294526_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	7.93945e-30

Protein sequences

>NZ_CP021983.1|WP_080813406.1|2294247_2294526_+|CRISPR-associated-endonuclease-Cas2
MLLYIVAYDIPSNRRRKKISDLLEGYGRRVQYSVFELMLSPAKYAELRRRLRRYVQMEEDSVRFYPVSKHTLDQVEIWGGVPLTQPPGSIIV
>NZ_CP021983.1|WP_080813407.1|2293250_2294243_+|CRISPR-associated-endonuclease-Cas1
MSTLYVAQQGCYVKLQQEQLLIKHNDAICQRVQLPLVDQILVFGHCQLTTQALRACLQRQVSVLYLSRMGQCYGRLLPMIQGYRQLARYQQDLSEVQRLRVAKILVKAKLWNSRVLLQRQGRTRPTPGIAQAVGQLAILIRQVNEARDNAALMGIEGAGAAAYFTALGDCFVQPGFTFTERNRRPPRDPVNAMLSFGYQVLWNHLYSLIEAQNLDPYEACLHQGSRKHAALVSDLLEPFRAPLVDSLVLYLVNRKVMDPEADFEPQKGGCYLNDSGRRKYLQAFVVRMETEITSSSTLPRPRWDLLMAQVQEYKRFVYEPQTLFKPYLIR
>NZ_CP021983.1|WP_088429762.1|2289695_2290115_-|hypothetical-protein
MSRQKRNSTALEQAERRLESLRSIARDLDLGRGLSVHNFAAILDDLATKLAAYNTALSNIDKMADDIRMAEKAARAMSEQMLMGVGSHYGRTSQEYEMAGGSRRKGHPRARVTANVPAPVVVPTTEPSQNGASATPVSV
>NZ_CP021983.1|WP_080813411.1|2288991_2289210_-|hypothetical-protein
MAQLTIDLPASISTDEAKLFLAAKLYEVGKLSLGKAAKLAGYSKSSFIELISKMDVPVVNYPADDLEQEIAL
>NZ_CP021983.1|WP_080813413.1|2288542_2288995_-|DUF3368-domain-containing-protein
MNAAVTNSTCLIGLERIQQLDMLPQVFTPITISPAVQSEVGISAPWLTIQAPQNRGIVRSLQTQIDEGEAATIALAMELGDVFVILDDLSARRIAQQLQLKVIGTVGMLLRAKQQGIISEVKPILDALTTANFRISEAIVRRAIQLADEE
>NZ_CP021983.1|WP_088429760.1|2287035_2288472_+|hypothetical-protein
MQTLIITVGTRQVGWRCADGTVCCFGADGDRNQHPRHTDRLYAELGIQRGCQDGYPWSVQDLGQRYYHRCRHDLDGTFDPVELLLDHEIIEAQYSQGLTDVVLWGTRQPDTTDASYRSRDTHWLAQLMAGKIRQTWPELTVAVFEPVVAATDSTAIRHALEDFLVQHTQGVEEVTLLIQTKGALPAIAHSLDICAAALVRQYPVLQVVPIEPVPLYSGDSQSANRSQHHQVISIGEYFWPIERLRIVAAWQQGNFSEAALWLMAHQDRHRLLYRLAQQLSLAANWQIEALFQPQGLGQWLQAGSLHQVVPATQIEIWRTQVEAIRHSPPAQTWECSFLVYLLLRQGNYTDAFMRFAQTLERLLYLRSQADQWFHADELQGRHPGFKQLIDRWFQSQGTPLPGPHYDQVDRIRNTRNQVVHQAKAMTLDDLCRLWPSTASTTAEALHGAMEHMLHQMYASSSGPSLLHALYDWGLSQLI
>NZ_CP021983.1|WP_080813417.1|2286649_2287012_+|hypothetical-protein
MTLKYLLDENVDSVYQVQIQRQEPEVIVFRIGMPGTPSIQSSDSDILCWCEEHSFILLTNNRKSMPVHLADHLAQGRHVPGIFILNNELSLGQQLEELILIAMASEETDFQDRITYLPIV
>NZ_CP021983.1|WP_080813419.1|2286321_2286645_+|DUF433-domain-containing-protein
MQLEDYFDFLAPDDIRLKGTRVGIETILYDFIHRCRTPEAIAQSYPSLSLEQVYATILYYLHNQEAVSAYLADWMEWSHQRREEQRQNPPPQVLKLRQLKAEKAASQ
>NZ_CP021983.1|WP_088429758.1|2285611_2285920_-|GIY-YIG-nuclease-family-protein
MPYTYILECADGSYYTGSTWNMARRLWEHQEGLGANYTAKRLPVRLVYCEECDRIDTAFQREKQIQGWSRKKKLALIASDMNQLHVLAECQNASHHENLHAD
>NZ_CP021983.1|WP_088429756.1|2283864_2285352_+|hypothetical-protein
MTTWILTIGSSDVLLKSDRNWNSLERQAQAKTRDLPHFRPSIVKMPNGADFFAFPVRALGIVYSSQLETYSSDLCLPRLETLCGQFRTSYPEHIIILLTDQAHLQPAARRKTHHAYWQDTCELKPILEFYLNQKFPDVSQDYLIVRPEPQGETIEVLGLDHWDSTLSLIQALMADIDDKSHKTIYVSHQGGIPALSSAVQFVTLTKFADKVQFLVSNEFQENSSELISSSTYLRGIRLQEAKRLLLRHDYVGVQELLRHGLLTSDDPLGSKIDSLLNSAILWNQAQFKQFSESLPLELQERTQEWWWAGYESAYLAMIRLEQGNTVEALFHSFRAAEGMLSNWAKWYYPDDIKEDKKGAPIVFLREDSHLPDYLKSKLAEKREKNKEANFMLYSQELFNLFQAVHPDASENENVKVIWKGAKGVRNQQFHRLLGLNEKEVFRAWGCKENRKAWEDRLLNCLNFIAGQDFKSLKDSSLMSRVQAELWGALNSVNLP
>NZ_CP021983.1|WP_088431631.1|2297065_2299498_+|endonuclease-MutS2
MIQQETLDLLEWPRLCQQVSTFAATKLGAIAAQQLVIPTHQGDSERLLAQTQEAYRLDELPPGLKFTGIHDIGDALDRAGCQGILQGDELLAIATTLNGARQLRRFIDSQEEVPVLSQLVSELRTYPELEQTIHHCIDERGRVADRASEKLTGIREKLNHCRDQIYQKLQRILQRQGQAIQQPVITQRGDRFVLAVKAPQKDAIPGIVHDSSTSGATLYVEPHSVVDLGNRLRQLQRQEQAEDDAVRRRLSHQVAAVQPDLEQLLAIVTSLDLATARARYSRWLAANLPRFTATNEQTTLRQLRHPLLVWQQQHEEGPEVVPIDVIIRPQLRVIAITGPNTGGKTVTLKTLGLAALMAKAGLFLPAREPVELPWFSHILADIGDEQSIEQSLSTFSGHIKRISRILAAIQEPGDRAKLDGEAASEEEATAAAPANALVLLDEVGAGTDPSEGSALATALLQSLADQAQLTVATTHYGELKALKYQDDRFENASVEFDEVSLSPTYRLLWGIPGRSNALTIARRLGLATQVIEQAEATLGTGSHQDVNQIIAGLEAQRQRQEDKAAEAAQLVAQAERLHQEVTDKARFLRQREQSLQQQQTQAIQAAVTQARAEIAKVIRRLQQGQATAQEAQQATDAVNKIAQQHQPAPAAPAKAKPGFRPQEGDRVRLPSLGQTAEVLSPADEDGKLTVRFGLMKTTVSLADVESLQGEKVEMPSKPKPQTTVPAAPAAPAVRTSRNTFDLRGLRVSEAEAVLDDALARAQGPIWIIHGHGTGKLRAGVQEYLKHHPQVQRFEAAEQADGGTGVTVAHL
>NZ_CP021983.1|WP_088429764.1|2299505_2300951_-|deoxyribodipyrimidine-photolyase
MAEQLLFWHRRDLRLADNLGLAAAYQRSPKVVGVFCLDPAILQRDDVAPARVHYMLGCLQELQHRYGEAGGQLLILQGRPQQQIPALAAALGAAAVYWHRDVEPYSRQRDQAVAEALKEKGIEMCTTFWDQLLQSPGQVLTGGGTPYTVYTPFWRKWVQLPKAEPVPAPESFEGLSDREQTALEQGGTVALPSLQDLGFEWSSPLPLAAGEWAAQRRLEEFCREDRAIAQYGEARNLPCEDGTSRLSAALKFGAIGIRTVWAMAEAAYSRCRSDETRQNIRAWQQELAWREFYQHVMYFFPELAEGPYRPQWQYFPWVNDKQQFQAWCQGRTGYPIVDAAMRQLNQTGWMHNRCRMIVASFLTKDLIIDWRWGEKYFMQRLVDGDLAANNGGWQWSASSGMDPKPLRIFNPASQAKKFDPEAEYIRQWLPELRHLDTAPLVTGQIPEEDCDRNGYPRPIVDHKRQQAIFKDKYKAEKAATT
>NZ_CP021983.1|WP_088429766.1|2301926_2303111_+|transaldolase
MASSLLEQLRQMTTVVADTGDIQAIEQFTPQDATTNPSLITAAAQMPQYQEIVDETLLKAKQDAGSAMSDKAIANLAFKRLAVAFGLKILQIIPGRVSTEVDARLSYDTEATLATARDLIAQYEQAGVSRERVLIKIASTWEGIQAATVLEQEGIHCNLTLLFGLHQAIACAQAGVTLISPFVGRILDWYKQETGQEYPPAEDPGVLSVTQIYNYYKKFDHTTEVMGASFRNIGEICELAGCDLLTISPKLLAQLDSIQEPLVRRLDPEKAKTMAIDPISMDEAAFRQMHRQDRMASEKLEEGINGFSKALETLERLLVERLCARMAGEKMVDHAAQDLFKACDLDGDGFITREEWLGTDAVFDALDLDHDGKITAEEINAGLGVAVKPAMAVA
>NZ_CP021983.1|WP_088429768.1|2303193_2303997_+|3-oxoacyl-ACP-reductase
MRLDGKVALVTGSSQGIGQVIAIRLAEAGAKVVINYRSHPEGAAETVAKIRAMGGECHGAEGYCDDDHAFSIGADLSILADIHRLVGESIDHYGQLDILVNNAGIEKHAPFWEVTEKAFDAVINVNLKGVFFTTQAVVKHLMATERSGKIINISSVHEDLPFPNFAPYCASKGGLKMLTRDLAVELAPYGITVNNVAPGAIETPINSELLNNQAKLNALLKNIPLGRLGHPQDVAGLVEFLASDDANYITGSTFFVDGGLTWNYQEQ
>NZ_CP021983.1|WP_088429770.1|2304406_2306092_+|alpha-glucosidase
MSSSSHAMPQPWWEEGVIYQIYPLTFADGNGDGTGDLRGIIARLDYLNDGDPDSETCLGIDAIWLSPINQSPMIDNGYDVVDYTDICPIFGTLADFDELLDQAHQRGIKIVMDLVVNHTSNQHSWFLESASSRDHPKADWYLWQDAWEGRDLPNNWQSYFGGTGWTYAEERGQFYFHTFNENQPDLNWQNPEVRAAIYDIIRFWLDRGVDGFRLDASSAYSQDPYFRDNPLKYGASDKNAYNNYHHLYDRNLPENHQIIKEIRAILEEYGDRLLIGETFIDNRLYDSIVFYGVNNDELHFPLTFEFPFSPWYPGYLQRQIEKTEKVTPVGAWPTYFLDNHDIPRHLSRWIECSLCVDSVAIAKAAATLLLTVRGTPILYYGQELGMVDNTEIPANKLQDRAVVKSGTGETPPPRDGARTPMQWDDFPQAGFSFGRDVDPWLPVHTNYHQLNVQAALQDPDSILTFYRQLIQVRRRSGALRRGQWRPLIHYPHEHLAYVRETEAETVLVLINFSYEKPLELDVLVNREAWTVLLSTTYKTGKLIDLPDTLQPFEVSIVQKLA
>NZ_CP021983.1|WP_088429772.1|2306241_2308269_+|glycogen-debranching-protein
MTVPLGRDICGDLPHAERREWLVTNGIGGYGCGTIAGLLSRHYHGLLVAALKPPLQRTLLLAKLDEQVIYGGQVYALGCNRWADGAVIPQGYRLIERFCLEGTVPVWTFAIADGLLEKRVWMEQGANTTYVRYTLVRASQPLTLSLQALVNYRDHHGNPQGPGWQMQGRPRPQGIEIRAFEGAVPFYLLAAGAEISPAHSWYRHYALAVEQYRGIYPYDDHLHGATVTVDLAVGQSLTLVASTGPDADLNGEAALRRQRLHEQGLLQQWHAAAGQDHPAWVHQLVLAADQFVVGRTVAGTPGKTVIAGYPWFGDWGRDTMIALPGLAIATGRPAIARPILRTFAQYLDQGMLPNLFPEAGESPGYNTVDAILWYFEALRAYYQASQDQALLAELFPALAEVIEWHQRGSRYQIHLDSDGLIYAGEPGVQLTWMDAKVDDWVVTPRIGKPIEISALWYNALVAMAQFAPVLGKSATPYQQLAEQTRQGFQRFWPGNRGYCYDVLDGPEGDDTSLRPNQIVAVALPASELLGPSLLSPVQQRAVVDSVAQHLVTSYGLRSLAADAPQYQGHYGGDRWQRDGAYHQGPVWGWLIGPFVQAHLKVYGDSSLARRFLAPLADHLSDGCIGSLSEIFDGDPPHRPRGAFAQAWTVAEVLRAYRLTVEAPREYQATTGLDMT
>NZ_CP021983.1|WP_080814380.1|2308274_2309138_-|inositol-monophosphatase-family-protein
MPSPTPRQILDTLLPYLKTAGAYARQIQPRIAAQPAKAAGSDNFFAAALSDADLSVQTFVEVALLAHFPELRFYGEEHAQTYNTKYFRAIDLGPQDDYLITLDPIDGTQFYLDGHDNYQIILTVLNQDEFEAVLAISPSQHCYYYTVRGQGTHRGHWQDTMADCRPLMVQPKTPAVCLGFALTALIDPLKDRYQVFHTGSSYSKQRQIPNFNGLLSGDLAGAVLERSQFIDGAALAFMAQEMGYWVTTWEGQPPPPLHQCRDMRRPGLVIGATAEVHRDLLAAVRTI
>NZ_CP021983.1|WP_088429774.1|2309246_2309933_-|KR-domain-containing-protein
MAQHILITGVSRGLGRAMTEEFISLGHTIWGCARQAEPVTALQNHYGPPHDFAVVDVANQDQVKAWGQSLLERHGPPDILINNAGVINALAPLWQVPPAEFDRVIDVNIKGVANVLRQFVPAMVQRGRGIIVNLSSGWGRSTSPQVAPYCTSKWAIEGMTRALAQELPATMAAVPLNPGIIHTDMLEVCYGDEAASFTALQQWKKQVVPFILQLSPKDNGRPLTVPGG
>NZ_CP021983.1|WP_080810632.1|2310020_2315396_-|hypothetical-protein
MLSIPGYQIIEKVYEGVRSVVYRAYEDLGQGSIILKTFKQAYPSLRDIARFRHQYEITKGLELDGIAKPYRLERHNNIIYLILEDFGGQPIYEVIGELARDVGTFLDTAIRITQCLGELHANQIIHRDIKPDNILINPKTSEVKLIDLGLSTRFSQERQEVGNPDSLEGTLAYMSPEQTGRMNRLVDYRTDFYSLGVTFYQLLTEQLPFTADDPLELVHSHIARLPTPPHELNPAVPVCLSNIVLKLMAKTAEDRYQSSQGLIADLTYCRDQWQQSKQIYEFPLGQLDVCDRFVIPQKLYGRERERQSLMEAFERVSQGAVELMLVCGFAGIGKSALIHEIHKPIVRQRGYFITGKFDQLQRNIPYASLIQAFQRLVRQVLSDSPERISQWREQLMAAWGQNGQVILEVIPDVELIIGPQPPLEPLSPVEAQNRFKQVFLQFVGVFAQASHPLVLFLDDLQWADFSSLSLLQELLLSPSLHHLLVIGAYRDNEVADGHLLTASLRELQAQQATIRRLVLLPLSLVDGTQLVADTLGCSIEQCDQLAQLIVKKTDGNPFFLTRLLTYLHEQGLIRRHGRQWYWNLQDIRQASIPDDVVDLVLGQLRQLPAAIQHCLMLAACIGNQFDLAILAVICEQPLVRVAQGLDDAIATNLITPLADTHRIIPHLAHSDAHPSEEIRVTYRFLHDRVQQAAYALLTDEHQRQSIHLKIGRLLLANQPISDQDASLFNLVNQLNYGAPLITETSERLQLAQLNLKAGQKAKASVAYDAALAYLSQGMALLSDSAWDQHYTLTYTLNKDRLECEYLCGHFDQAQQLFQHLTEHARTLVDIAEIYGLQIVLYTTLGRFADVIHLGYEGLAKLGWSVPTTPQQVKLAVWKELLWIKWHLLGRRIPRLLQRSPLQDPVQLAKLNLMAQVIPTLYYTDMEASNLFYLKMASLSLRHGNAPASAVAYLGLGRLLGEKLGEFQNRYQFGQLAIQLVEASNSKALKCKTHFLFGGFIHPWTQPAQGDLTYLRSAYQAGMDAGDLIWACYANNVLSMRLFFLGRQLVEIESEAQRFLIHAQQVKEQYTPTFLVVTRQVARCLQGNTNSATNLSDADFDEAAHLNLLQTQPGLVGALNWYYVTKTLLCFLANDPDAALAAAQQADKTIGAAMGLYRVAAHSFYYALCCVTAYQRQRDPARRQYIWQTLQRHWQKLHRWATHSPANFRHKADLIQAEMARLKHQFPQAERLYQKAIRGAREAGYLQNEALANELAADFYDGRGLDVIGRAYRIEARYAYLQWGAISKVQSLDEAYPFLGGTLDGLFPGAGDTLTPSVSSYGSTNSQPGDLDLKSVIKATQALSGEILLDKLLTTMVHTLLENAAAQRVVLVLTYRGAPTIEAEGWSDRDAVQILQATPVGEVTHLSQHIVNYVLRTGESVVLANATEQGPFVHDPYVVQHQPKSLLCAPLTTQGKLLGLVYLENNLTVDTFTPGRLEVINILSAQVAISIENANLYTNLAALNQAYERFVPHEFLQFLERDSILDVQLGDQVLKRMTVMFADIRAFTALSEQLSPKENFDFLNTYLKRVGPVIRQHRGFIDKYIGDAVMALFPQSADDALTAAIALQQTVVAYNVERQSQGGMLPIRIGVGLHTGNLMLGTVGEEERMESTVISDSVNLANRVEGLTKLYGNYITLTGDTLGDLANPVRYQYRFLDRVRVRGRENPVEIYDVFDGDNEQQRHLKVATRTTFEQGVCLYYAEQFHEAEPIFQDVLAQNPRDQAAQLYVQRCQTYRDTGFPPGWDGVERLDLS
>NZ_CP021983.1|WP_080810634.1|2315792_2319440_-|methionine-synthase
MVTAFLERLQSPDHSVIVFDGGMGTNLQVQNLTADDFGGPQYEGCNEYLVITKPEAVAKVHRDFLEAGADVIETDTFGGTSVVLAEYDLADRAYEINRAAAQLAKQVAADCSTPDKPRFVAGSMGPGTKLPTLGHIDFDTLKGAYVEQAQGLLAGSVDLLIVETCQDVLQIKAALNAIMEVFEAGARRVPLMVSVTMEQQGTMLVGTEIAAALTILEPYPIDILGLNCATGPDLMKDHIKYLCQHSPFVVSCIPNAGLPENVGGQAVYRLTPMELRMALMHFVEDLGVQIIGGCCGTRPEHIQQLAEIAQDLHLKQRPVRLALQPSQEPWPEPRPRLNYVPAAASIYSPQPYDQDNSFLIIGERLNASGSKKCRETLNAEDWDGLVALGRSQVREGAHVLDVNVDYVGRDGERDMHELVSRLVTNVTLPLMLDSTEWTKMEAGLKVAGGKCILNSTNYEDGEERFLKVLELAKRYGAGVVVGTIDEEGMARTAEKKFQIAQRAYRAALEYGIPAHELFFDTLALPISTGIEEDRGNGKATMEAVGLIRENLPGCHIVLGVSNISFGLNSAARVALNSVFLHDAMERGLDAAIVSAAKILPLAKIEPEHQQICRDLIYDRRQYDGDICTYDPLTKLTTLFAGKSVKKKEAIAKDLPIEEQLKQHIIDGERIGLEEALEKALKTYEPLDIINTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAYLEPLMEKSDSDGSGKGIVVIATVKGDVHDIGKNLVDIILSNNGYKVVNLGIKQPVDAIIQAYRQHNADCIAMSGLLVKSTAFMKDNLEVFNEQGITVPVILGGAALTPKFVYQDCQNTYKGKVVYGKDAFSDLHFMDKLMPAKAATNWDDLQGFLDEVDAQAGGEDKAEQAVANREQQGDSSGQPVEGKEQVDATTALPDTRRSEAVDLTMPRPTPPFWGTRILNPEHIPLDEVFWYLDLQALFVGQWQFRKQKGQSREEYEAFLQETVHPILAEWTQRVQTEALLHPQIIYGYFPCLAAGNSLHIYDPSVVDGKMAPPEPIAIFDFPRQKSMRRLCIADFFLPKELAQPGQFDVFPMQAVTVGEVATAYAQQLFQSDRYTDYLYYYGLSVQTAEAMAEWCHARIRQELGYGDQEPATIREVLQQRYQGSRYSFGYPACPNIQDQAVQLELLACDRIGMTMDESEQLYPEQSTTAIIAYHPVAKYFST

Crispr_ID: NZ_CP021983_17

• CRISPR_ID: NZ_CP021983_17
• CRISPR_location: 2567342-2567427
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_CP021983_17

Consensus_repeat	Method
TTTTTGCCGGTCCTTCTCTATAGT	CRISPRCasFinder

spacers of NZ_CP021983_17

>17.1|2567366|38|NZ_CP021983|CRISPRCasFinder
CAGACGGGACCCATTGATTTTTCTTTGGGACGCAATCA

CRISPR arrays and Neighbor proteins around NZ_CP021983_17

CRISPR arrays

The CRISPR arrays of NZ_CP021983_17

>merge|NZ_CP021983|17|2567342-2567427|CRISPRCasFinder
TTTTTGCCGGTCCTTCTCTATAGTCAGACGGGACCCATTGATTTTTCTTTGGGACGCAATCATTTTTGCCGGTCCTTCTCTATAGT

>NZ_CP021983|17|18|2567342-2567427|CRISPRCasFinder
TTTTTGCCGGTCCTTCTCTATAGT	CAGACGGGACCCATTGATTTTTCTTTGGGACGCAATCA
TTTTTGCCGGTCCTTCTCTATAGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_080813045.1|2559351_2560128_+|glycosyltransferase	unknown	unknown	gnl|CDD|224833
NZ_CP021983.1|WP_080813032.1|2553673_2554867_+|hypothetical-protein	unknown	unknown	gnl|CDD|340860
NZ_CP021983.1|WP_088429889.1|2567824_2568931_-|hypothetical-protein	unknown	unknown	gnl|CDD|319862
NZ_CP021983.1|WP_080813064.1|2572250_2572442_-|DUF2949-domain-containing-protein	unknown	unknown	gnl|CDD|371402
NZ_CP021983.1|WP_080813029.1|2552742_2553696_+|hypothetical-protein	unknown	unknown	gnl|CDD|133055
NZ_CP021983.1|WP_088429895.1|2572673_2573036_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080813043.1|2557899_2558697_+|hypothetical-protein	unknown	unknown	gnl|CDD|274008
NZ_CP021983.1|WP_088429893.1|2571306_2572218_+|DUF1838-domain-containing-protein	unknown	unknown	gnl|CDD|378086
NZ_CP021983.1|WP_088429903.1|2574964_2575279_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088429883.1|2556676_2557858_+|glycosyltransferase-family-1-protein	unknown	unknown	gnl|CDD|340831
NZ_CP021983.1|WP_088431647.1|2554875_2555775_+|hemolytic-protein-HlpA-like-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088429901.1|2574557_2574824_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088429887.1|2564623_2567146_+|polymerase	unknown	unknown	gnl|CDD|377422
NZ_CP021983.1|WP_088429897.1|2573394_2573853_-|glyoxalase/bleomycin-resistance/dioxygenase-family-protein	unknown	unknown	gnl|CDD|319917
NZ_CP021983.1|WP_088429899.1|2574043_2574430_-|ArsR-family-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042
NZ_CP021983.1|WP_088429885.1|2561866_2564620_+|hypothetical-protein	unknown	unknown	gnl|CDD|273357
NZ_CP021983.1|WP_088429891.1|2569217_2571227_+|DUF4157-domain-containing-protein	unknown	unknown	gnl|CDD|379338
NZ_CP021983.1|WP_088429905.1|2575881_2576427_+|DUF4168-domain-containing-protein	unknown	unknown	gnl|CDD|379360
NZ_CP021983.1|WP_088431649.1|2560181_2561597_+|sugar-transferase	unknown	unknown	gnl|CDD|274398
NZ_CP021983.1|WP_080813039.1|2555785_2556673_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|372616

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP021983.1|WP_088429899.1|2574043_2574430_-|ArsR-family-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	4.6e-14	47.6	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_080813045.1|2559351_2560128_+|glycosyltransferase	gnl|CDD|224833	COG1922, WecG, Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane].	3.39448e-81
NZ_CP021983.1|WP_088429889.1|2567824_2568931_-|hypothetical-protein	gnl|CDD|319862	cd16383, GUN4, porphyrin-binding protein domain GUN4. GUN4 is a porphyrin-binding protein involved in chlorophyll biosynthesis regulation and intracellular signaling, found in aerobic photosynthetic organisms. It has been implicated in retrograde signalling between the chloroplast and nucleus. GUN4 can bind protoporphyrin IX (PIX) and magnesium protoporphyrin IX (MgPIX), substrate and product of the Mg-chelatase, as well as heme and cobalt protoporphyrin IX (CoPIX). It may play a role in protecting plants from reactive oxygen species (ROS)-mediated damage.	8.02847e-60
NZ_CP021983.1|WP_080813064.1|2572250_2572442_-|DUF2949-domain-containing-protein	gnl|CDD|371402	pfam11165, DUF2949, Protein of unknown function (DUF2949). This family of proteins with unknown function appear to be restricted to Cyanobacteria.	7.90576e-24
NZ_CP021983.1|WP_080813029.1|2552742_2553696_+|hypothetical-protein	gnl|CDD|133055	cd06433, GT_2_WfgS_like, WfgS and WfeV are involved in O-antigen biosynthesis. Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	2.51883e-32
NZ_CP021983.1|WP_088429899.1|2574043_2574430_-|ArsR-family-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	4.20253e-19
NZ_CP021983.1|WP_080813043.1|2557899_2558697_+|hypothetical-protein	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.000350463
NZ_CP021983.1|WP_088429893.1|2571306_2572218_+|DUF1838-domain-containing-protein	gnl|CDD|378086	pfam08894, DUF1838, Protein of unknown function (DUF1838). This family of proteins are functionally uncharacterized.	9.66953e-86
NZ_CP021983.1|WP_088429883.1|2556676_2557858_+|glycosyltransferase-family-1-protein	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	7.8865e-52
NZ_CP021983.1|WP_080813032.1|2553673_2554867_+|hypothetical-protein	gnl|CDD|340860	cd05844, GT4-like, glycosyltransferase family 4 proteins. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to glycosyltransferase family 4 (GT4). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	1.40913e-116
NZ_CP021983.1|WP_088429887.1|2564623_2567146_+|polymerase	gnl|CDD|377422	pfam04932, Wzy_C, O-Antigen ligase. This group of bacterial proteins is involved in the synthesis of O-antigen, a lipopolysaccharide found in the outer membrane in gram-negative bacteria. This family includes O-antigen ligases such as E. coli RfaL.	1.65513e-12
NZ_CP021983.1|WP_088429897.1|2573394_2573853_-|glyoxalase/bleomycin-resistance/dioxygenase-family-protein	gnl|CDD|319917	cd07254, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	2.51596e-47
NZ_CP021983.1|WP_088429885.1|2561866_2564620_+|hypothetical-protein	gnl|CDD|273357	TIGR00947, 2A73, putative bicarbonate transporter, IctB family. This family of proteins is suggested to transport inorganic carbon (HCO3-), based on the phenotype of a mutant of IctB in Synechococcus sp. strain PCC 7942. Bicarbonate uptake is used by many photosynthetic organisms including cyanobacteria. These organisms are able to concentrate CO2/HCO3- against a greater than ten-fold concentration gradient. Cyanobacteria may have several such carriers operating with different efficiencies. Note that homology to various O-antigen ligases, with possible implications for mutant cell envelope structure, might allow alternatives to the interpretation of IctB as a bicarbonate transport protein. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	5.01076e-14
NZ_CP021983.1|WP_088429891.1|2569217_2571227_+|DUF4157-domain-containing-protein	gnl|CDD|379338	pfam13699, DUF4157, Domain of unknown function (DUF4157). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 80 amino acids in length. This domain contains an HEXXH motif that is characteristic of many families of metallopeptidases. However, no peptidase activity has been shown for this domain.	1.43537e-31
NZ_CP021983.1|WP_088429905.1|2575881_2576427_+|DUF4168-domain-containing-protein	gnl|CDD|379360	pfam13767, DUF4168, Domain of unknown function (DUF4168).	1.07204e-08
NZ_CP021983.1|WP_088431649.1|2560181_2561597_+|sugar-transferase	gnl|CDD|274398	TIGR03025, EPS_sugtrans, exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase. Members of this family are generally found near other genes involved in the biosynthesis of a variety of exopolysaccharides. These proteins consist of two fused domains, an N-terminal hydrophobic domain of generally low conservation and a highly conserved C-terminal sugar transferase domain (pfam02397). Characterized and partially characterized members of this subfamily include Salmonella WbaP (originally RfbP), E. coli WcaJ, Methylobacillus EpsB, Xanthomonas GumD, Vibrio CpsA, Erwinia AmsG, Group B Streptococcus CpsE (originally CpsD), and Streptococcus suis Cps2E. Each of these is believed to act in transferring the sugar from, for instance, UDP-glucose or UDP-galactose, to a lipid carrier such as undecaprenyl phosphate as the first (priming) step in the synthesis of an oligosaccharide "block". This function is encoded in the C-terminal domain. The liposaccharide is believed to be subsequently transferred through a "flippase" function from the cytoplasmic to the periplasmic face of the inner membrane by the N-terminal domain. Certain closely related transferase enzymes, such as Sinorhizobium ExoY and Lactococcus EpsD, lack the N-terminal domain and are not found by this model.	5.8952e-131
NZ_CP021983.1|WP_080813039.1|2555785_2556673_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|372616	pfam13489, Methyltransf_23, Methyltransferase domain. This family appears to be a methyltransferase domain.	7.65309e-33

Protein sequences

>NZ_CP021983.1|WP_088429887.1|2564623_2567146_+|polymerase
MKSTSTSQDGTLLGLLTVALYAVFTLLPGSSTMMVSWPWVFLWQAALALPILWLLWQLWHKPLRAFRLGGGLDWIVALGVIGLIVSTLGAEFPQQARWYGWAALGGVAAVYALRGWLTTPRRCLRLLQGQGGLAIAFILVSLGLWLSQIYWPELARLETLQQYGVEQSFNFNLTSLRNWQPIGHQNYVAGYLVLMLPLLAGLAWVGRGWQRWLWLGGGLLGLVDLYTTSSRGGWLALIATAVVALAVALLRSPLPKKVVLPAGAVGVIALVGLALANPRIRQLVLALLSGRTQSGELAYRFITNAVGWAMGKAHPWSGIGLGGVPVAYQAYRPAWAGREAELQFQLHGTPAQLWAELGIWGILIPLLLSGWGLYCTWRWLRHPSPNQLLAPLVWSLLAGLLACGLISLTDYQLDILCISGGLALYGAVLATTFHSPGSASSPPQRITRGLVGLGLGLTVAMGVWLVPIHRAWQLSSQGFAAIRQDDLPTFVQTLERAHQLAPWEPYYPYQLGWKLGDLSYQAPPEVAERLRRDAITWFQRGLKASPYQEFGHSNLGWLQVQVEPKAAVQSFTRSAQLVPAKQGVFFGLGFSLLRAGQPEQATEAMVLELLRHPLGLTSPVWQTGQFSPLYAPMLASLEARYSEFLEQLAPGNGLTRYLHQLRGSLRWWQGDLAGAEADWTIGGTVISRAVLDLAQGQPVDAAALPDSPGKFAILAWQTPSERRALLEKAWVTQPEDLPQLEEGLPPPEMIDQLVQSMRAAESFDQWLHIAPTWEPRSKRLGFGVLSRHIDGLLPADYLPRIENVAMVKFFEELLPSPTYRPEWDRALQPQRQGLIQSLAM
>NZ_CP021983.1|WP_088429885.1|2561866_2564620_+|hypothetical-protein
MVSWPWIAIWQGGTLLLGLATIGQLRRFQRPWRGLGYGFDGLVLATALGLTLATVVAPFPTVAAWTLTQGLGYGLLLYVARNALSQPRFSSTVLWWGLAGMAVGVAVISLSYWRPDAAMWQQGNFCNAIRNLYPLGHHNFVGGYFALTLPLAVALALAQSGWRRWLGLGLALVVALALYVSGSRGAALGLVVWLLVTLVSVVGRRQGKQRWRLGLLGLVLLLLVTAAMATNPRVRDLMQGLALDPDEPVAVAVSDGPARDRIFMLGTAANILRDRPLLGIGPGNMGRVSNRYRPIEAGAGLDHVQQLHNTPAQLAGELGLVGIGLYLAWWVLVGRLCWRLHRAPLTPPDRTLLYGIGGSYLAYGVSSLTDYQLENIPIAVTLSLSLVMLLGLADTYLVKDTAAMSWPQRSRRWTSLGVLALVALAIRLWLPFDLSLALGQSAISQLQQQNLVTADSRWQKATRLAPWDPTFGALAGEELLQVESWADSDSNQQVIRQAVYDYFHQAQAAAPNDVWFNQNLAVLYYQDGDWQQAEHYGRRAAQLLPRNQSFIYALLGLIYLAQESPDQAVAALAIEALVHPDFLTYPAWQQPPLAAVYPQVVEATLGHYDTLLVDVSPATPGYDRLQTNVQALRWWLGRPIPSADQSKRTSTVALHQNGRGLLLEEWGRPEAAFHLPFSPRGRRGWGMRERPNQQGGHNLCALSSEGEAAASLSHSPAPLVGVRAGGRGVATGHKQSTATESSFIKSSVLRPPPSALLRTLMLAEPDPEQALDVLNQAIAAGDGSPSLQLLRAWLAPEVYLDDYLAATDLSDQERQVLQGHMLEERNLRDWMRSLTQAVTARYRGSLAFSYRNRAANQISLILQPTELETYTLVEQLGLFRDWPREFPALDYQIERLCIQALNLPHPTCQDRTAAPCG
>NZ_CP021983.1|WP_088431649.1|2560181_2561597_+|sugar-transferase
MPHRDIRAPRTPQLKQIWTWRWQRVLLLVLSDILALTVAWRIAHFLNQFFSPIPDQLVWWVWLDLPSLFWIFVPVTLAVFAQYGLYGPLTQVKNYVRAAQLITAIYLLSLVLVYFYDPKLDPPRSLFFSAWGSSVALVMLARLLVTLVLRPIEQRWVQGRLFLIASARRLKLLSDTLQQRSSMTVVGSALATTANSPITLQAILKSGAQLVLAEDLPDATLASSLYWQLRRAGIALRLVPSSREMLYRRGVPEIFAGIPTLRLDAPLVDGLDYRLKRTLDYVGAALGMLVLAPLLLGAAIAIRLDSPGPIFFRQERIGLHGKVFPMWKFRTMAADAARQQITLETQNQSQDGILFKLKSDPRITRVGQFLRRTSLDELPQLFNVLWGQMSLVGPRPLPLRDVAHFDAGHHVRHQVLPGITGLWQISGRSDIGSFDDAARLDLHYIDNWSLNLDLDILMETLKIVLLGKGAY
>NZ_CP021983.1|WP_080813045.1|2559351_2560128_+|glycosyltransferase
MRALPARDILGVRVDGTSYGDACDRIWAWTESGTPAYVVAANVHVIMTAYWNRAFRRVLRRAALVTPDGMPLVLGLRWLGLTGQGRVYGPDLMLAWCQRAARAGLPIYLYGGSEATLAQLRVNLSDWFPDLKIAGSHAPPFRSLTPAEDIVDRQRIQASGAKVVLVGLGCPKQEHWMARQVSHLPLVMIGVGAAFSFHSGTVAQAPRWMMGCSLEWLYRLGREPRRLWRRYLINNPAFMLLFGLQLLRQRLGLASSQP
>NZ_CP021983.1|WP_080813043.1|2557899_2558697_+|hypothetical-protein
MQSQEQLQRRLSAAFDERQAAVLAEVVTEAYSELVKTHDFNELKEIVRELAQAQTRTEQQVDTLALRMDELAQAQTRTEQQVDTLALRMDELAQAQTRTEQRVDTLAVRMDELAQAQTRTEEAVRELAEGQRDLRRQLGGLAMTVGYRLEDDAYKALPALMERDHGVRVQGRLKRGYLNDAQGRSLEVNILGNAIWEGEPATIIGESKSQLSAPEIERFIRRRLQPLQQVLPRVFPVLVTHMVSGPEVDDYARQRGIALYYSYDF
>NZ_CP021983.1|WP_088429883.1|2556676_2557858_+|glycosyltransferase-family-1-protein
MRLLYTLTSYRPALGGAQIHTHLLAQHLAEHHAVQAVCHWDHNRSDWLLGTTLRQPPARDYEIDTISVHRLGFSWTEKLRMAIWLPLYYPLMQVALPPIAGEVARHLHPLAQSADLIHNVRIGREGLSYASWQTACQYDIPFVFTPVHHPRWVGWRYRAYIELYRRADAVIALTPSEKSTLIDLGVAPDHIHVTGIGPVLAEQADAQRFRRQYGLEAPMVLFLGQHYPYKGFRQLLEAAPLVWQHHSDTQFVFIGPPVKDSDQVFLAYTDSRIHHLGPVDLQAKTDALAACDLLCVPSSQESFGGVFTEAWSLGKPVVGGRIPAVADVVYEGTDGFLVAQDPDQIAERICYLLAYPERAQAMGQAGQAKVQQHYTWPTLAQKTEQVYRAVLGI
>NZ_CP021983.1|WP_080813039.1|2555785_2556673_+|class-I-SAM-dependent-methyltransferase
MDSQSARISGSKESSILCPICQSRRQRELYPTHGGQLVRCCDCQVVLFTPRPSQAELDRYYNAQSYYEHYQSSPMGQAVFAQHRYQQLCRVLRRYAPYLLTQQPRVMLDVGCGTGQLLAVAATQGWQIQGIDLSAAAVKQAQEQLGPVVQRGTIAEIASSPNIYDLITSYHVIEHLLDPVLLLRHIYKVLRPGGAVFIETPNIDSLGARLRGNRWSHIIPPEHITYFNPTSLQRALQQAGFQTIQTLTIRPQVIESLAHIPLFLKGIASLAYTVAPWMNLGASLQAIALKPSCHG
>NZ_CP021983.1|WP_088431647.1|2554875_2555775_+|hemolytic-protein-HlpA-like-protein
MHTPVALIIFNRPELTQKALEAIALVQPPVLYVIADGPRTGHPSDAAACKQTRALVDQIPWDCQVIKIYADNNLGCRERVSSGLDWVFNHTETAIVLEDDCIADPTFFHFCEQLLERYRDDTRVMAISGDNFQRSRQPRTPYSYYFSRYPHCWGWATWRRAWQCYDNTMALWPNIRDGCWLYDLLESRFEVAYWRRVFQKVYDNQINSWAFRWTFACWLHSGLAILPRVNLVSNIGFSSYSTHTRNRSSPFAALPVAAMPFPLKHPPFMIRDVQADRFTYQTMYSPLVRARAKLRQWLP
>NZ_CP021983.1|WP_080813032.1|2553673_2554867_+|hypothetical-protein
MIQSQDDNQPTNVLIYRDLLLPYSETFIKNQVISLTKYRGIYAGTLTNKSHPDLLEAEQVISLDRIVQFSLPWRLLFKFFGMVHPDWIRAIRQQSPVLLHAHFGPDAVWAMPLARQLKLPLLITFHGYDATLSEGLSAFTNRLYGLYLKRRNSLFNQAQGVIAVSKFVQSQLEAKGCPPDKIYQHYIGIDTAYFCPDRQQQRSPIILFVGRLVEKKGCFPLIQAIARVQQVTPDIELILIGDGSLRSALETEATAHLKRYQFLGQQPPSTVRDWMNRAKVLCVPSQQAASGDTEGLGMVFLEAQAMGLPVVSCRSGGIPEAVVHGETGFLVPEGDVNGLAQHIVRLVEDAPLWQRLSHQGRAWVCDRFDLQTQTRKLEAIYDTVLAEHQRKRLGSRC
>NZ_CP021983.1|WP_080813029.1|2552742_2553696_+|hypothetical-protein
MSDPPLVSILINNYNYGEFLPQAIDSALQQSYPNLEVIVVDDGSQDDSAAVIKNYQGNIITVLKQNGGQASAFNAGFAASSGEIVCFLDADDFFLPEKVETIIHWFHKFPNIGWIFHELDYVDRDSNLLSVNRKIADFECQRIDLRHILRESGKIPYSIPCATCGLCLRRDVLDQILPMPESRSVTISDNYIKLSALALSPGIILSQRLAAQRIHDRNIYTFRPDATKLSAEISLKTGYYLRERFPEIEKFTDKLFAKGLGTMIGAIGLKGALSLPETNRYLKRFSTWQSLLRVILSRTVFYTLKSSMKKNDPKPGR
>NZ_CP021983.1|WP_088429889.1|2567824_2568931_-|hypothetical-protein
MPDSSDYQNRLELFNRLTALPTPQLGSLIFALNPPEGNVPPPSAAPATRIEALLTWVESPIGCRLDTLKAVLNEIDASQQLSPSQYQTPGPQPQAAAEQYQQEVVRIVSEGNGTITETERIFLDVLQEHLSIPAAEAQRIQQRCLSPYASYRNMVERLVEQSYPLTSAAKHTLQRSRRKFSLSDLAANQIEKSVLWGEDDLSSEQGIDYVRLRRLLKACDWKGADQETIDRMLDAMGKRSWYAISDEDLLNFPCADLKTIDRLWVKYSHGRFGFSVQQQIYIECGATFDGKCPDDWQIRRNLLEQFERRVGWRKRGLERGQTYYYYDVTFSTSSPKGHLPALYNSGGGCYDSIQVLEVGLASRLADCS
>NZ_CP021983.1|WP_088429891.1|2569217_2571227_+|DUF4157-domain-containing-protein
MRIFTKAARRPSVSLLRGTDRARLSNGLDQRRSLVHLQRSPFTISSPRDSYEQEADRIAEQGMHMPEPQLQQRCACGGGCPRCEQAQGGDKSLLTKRVYPPSLGGASAPPSVQTVIASSGQPLDTRIRRSMELRLDHDFSQIRIHTDGRAAQSAEEIGAIAYTSGTNIAFARGKYQPGTVSGQRLIAHELVHVVQQSGPDNLSRKAFIQRACLPDPECEPPDTGEARVGSAKRFGEEVTEKAAPKRAERKKLPPETARSGLHGRPAEAVEHLFQEHISDLRPVIHGVFVDEDLPDDVGASRADCLQWAQVSLPPGTKVPEFEGAVHSCIFVPAALERQAAIYNSGGVPDPRFTRQEWLRWAVLRVLTHETTHARFLGANIRYPSSDENCTEERLAKEISELAAVISEFPFVNRLKQDLQDAWFNHHLKDPTEVTGESISGAIRDIRCSCECPDADAMIRAAFEFASSSWTERQKQTFHAHMKRGKGKEFDIYWPYDASRTGRVGRHELSLAAGVGFSGSDKLKVAMLTYRYVMWNWVEGRLRVTGGVQLNLASLFESDPHGEFGAAIGGLQFVSTPVSRDKRFGGFTGRLETGFGLGEFTLEPVAPQSRETTVSSRDWVLQVSGGVQFFIPRFTHLRPVSIEAAYRLAQPLDSDARQINTFSISAILPL
>NZ_CP021983.1|WP_088429893.1|2571306_2572218_+|DUF1838-domain-containing-protein
MMTQPLPSTFLTMALGMGLMIVSLGCPGAEARSLDLSRPEDTLQAFRKLLCSVEDGRTVYYGWVGQVYSRVPGERDRHLFNVQGVSTRACVSLTSETGSPGFRQVSREVMLYLDPETDAVLEHWDNPWTGERNRVMAVANDPVNSSPFWAETTGQRLQFQWLGETDTLFLSVVIPLFYPNPLGSDYQDYVGGYYHAMELFNFAVDRSDLLGSDREEVSQVALSWSRISPWLPWMEMGGRPGEMVFQAASTRLEDWRQLPQPLRTQMETEFALYQEPPPLDDDRPNETTWTNFRHYLEALPTME
>NZ_CP021983.1|WP_080813064.1|2572250_2572442_-|DUF2949-domain-containing-protein
MSKQARLVEFLNQELAVPTDAIALGVRQSASMPNLLPMVLWQYGIVTTYQLEQIFDWLEASTG
>NZ_CP021983.1|WP_088429895.1|2572673_2573036_-|hypothetical-protein
MTLSTLIQRSRTWLRTVAIALLASMVGLMIGVNNPAYADTAEESVEYIAADGSDLTAVAQCLPQELSQPSLARALSESGNDFLEKVFDVKDDYGDYELDSTEVEYLNCLKQTGVTPQVER
>NZ_CP021983.1|WP_088429897.1|2573394_2573853_-|glyoxalase/bleomycin-resistance/dioxygenase-family-protein
MANLKTHVALHVADLHRSVSFYRAMLGTEPVKYKADYAKFDLDNPGLNLALNASDAMVRDRPFRAIETPGTLSHLGIQVDSREAVREAISRFQTAGLITFAEPDTDCCYALQDKVWVTDPDGNRWEIFVVTIADTTPDMNLTTSQDQRACCD
>NZ_CP021983.1|WP_088429899.1|2574043_2574430_-|ArsR-family-transcriptional-regulator
MEASHSSPSSIDGIAATFAALGQPSRLRIVRLLLSAYPQGLPAGEIQKELGISAPTLSHHLDKLRQVGIVTAKKDRQWIWYAVRSQVLKSLIDFLFAECCTRNQVVAFDPSAWPSDWGEAEGSSGCCD
>NZ_CP021983.1|WP_088429901.1|2574557_2574824_-|hypothetical-protein
MDLDRAMFNPASVFASPGAVCDAQDLSHAQKVEILRRWEYDARELQVAAEENMGEGSEELLDEILAALHQLGAGIDLDNSPPTKQGGF
>NZ_CP021983.1|WP_088429903.1|2574964_2575279_-|hypothetical-protein
MAAKNGGKNSPNLVHQFKSSCKTPVIKGFRGAELLRLPQLIMSRLIDLEILQSAATSPMTQAIAPPLNFLEFLETLPDDGNRYELVNGERVQRMATRAHDDVAD
>NZ_CP021983.1|WP_088429905.1|2575881_2576427_+|DUF4168-domain-containing-protein
MVNHHSDDPSNRKLYMLLRSLLLTGSLLASLGAGALPVAAQAPPQQTPPQQAPTPSQAEVSAETIDQFVAAFKQVQAIRESAQAEMAAAVEAEGLTIEEFNAMVEAQQDPDSQASMDLSQQDIERFMAAADQVSTIQQEAQGEIEAAIQEEGLAVEEFSQIMALAQQDPELREAINQRLNE

Crispr_ID: NZ_CP021983_18

• CRISPR_ID: NZ_CP021983_18
• CRISPR_location: 2822496-2823556
• CRISPR_type: TypeI-D
• Repeat_type: NA
• Spacer_info: 14 spacers
• Cas_protein_info: cas2,cas1,cas4,cas6,csc1gr5,csc2gr7,cas10d,cas3

Consensus repeat of NZ_CP021983_18

Consensus_repeat	Method
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAA	PILER-CR
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	CRISPRCasFinder
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	CRT

spacers of NZ_CP021983_18

>18.1|2822532|37|NZ_CP021983|PILER-CR
CTTGTCCTCAGTCCGGTATTTGGCGGTTTCTGCGGCG
>18.2|2822605|37|NZ_CP021983|PILER-CR
CGCTTACTCAGAAAGGGAGGTCAAGAAGGTCCTCTTT
>18.3|2822678|36|NZ_CP021983|PILER-CR
CAGGAAAATGCAACGATATTTTGTGATTGAGCCCTT
>18.4|2822750|38|NZ_CP021983|PILER-CR
CGCGGCTAAGATGCGGCAATAGCACGACACTATGCCTA
>18.5|2822824|37|NZ_CP021983|PILER-CR
CCGATCAGTCAAGGTGGTGTGGGACAACCTGCTGCCT
>18.6|2822897|39|NZ_CP021983|PILER-CR
CGCCAAGTGGCGGGGGAGTGGGGCATGGGCCAGTGAGTA
>18.7|2822972|47|NZ_CP021983|PILER-CR
GACTGAAACCTAGCAGTGAGATATATGGTGAACGCTCCCCCCAGGCT
>18.8|2823055|35|NZ_CP021983|PILER-CR
CACAGCAAAGATGCCAGTAATGCCGTGCAGTACAG
>18.9|2823126|37|NZ_CP021983|PILER-CR
CCGCCCCATGTAGGTACGCCCCACGCAGGTTAGCCCT
>18.10|2823199|36|NZ_CP021983|PILER-CR
CCGACCCTGTGGGCCGACTGTGGTTGGCCTGTAGAG
>18.11|2823271|37|NZ_CP021983|PILER-CR
CAGATCCCTTATCCCGATGCGTCCACTCCGAACACAG
>18.12|2823344|38|NZ_CP021983|PILER-CR
CCTATCCAAGCGGACGATCGATTTGCCGTTGGTGTCAG
>18.13|2823418|36|NZ_CP021983|PILER-CR
CATGCCAGAGCCTACCACCAGCAGCACCCCTGCCAA
>18.14|2822533|36|NZ_CP021983|CRISPRCasFinder,CRT
TTGTCCTCAGTCCGGTATTTGGCGGTTTCTGCGGCG
>18.15|2822606|36|NZ_CP021983|CRISPRCasFinder,CRT
GCTTACTCAGAAAGGGAGGTCAAGAAGGTCCTCTTT
>18.16|2822679|35|NZ_CP021983|CRISPRCasFinder,CRT
AGGAAAATGCAACGATATTTTGTGATTGAGCCCTT
>18.17|2822751|37|NZ_CP021983|CRISPRCasFinder,CRT
GCGGCTAAGATGCGGCAATAGCACGACACTATGCCTA
>18.18|2822825|36|NZ_CP021983|CRISPRCasFinder,CRT
CGATCAGTCAAGGTGGTGTGGGACAACCTGCTGCCT
>18.19|2822898|38|NZ_CP021983|CRISPRCasFinder,CRT
GCCAAGTGGCGGGGGAGTGGGGCATGGGCCAGTGAGTA
>18.20|2822973|39|NZ_CP021983|CRISPRCasFinder,CRT
CCTAGCAGTGAGATATATGGTGAACGCTCCCCCCAGGCT
>18.21|2823049|34|NZ_CP021983|CRISPRCasFinder,CRT
ACAGCAAAGATGCCAGTAATGCCGTGCAGTACAG
>18.22|2823120|36|NZ_CP021983|CRISPRCasFinder,CRT
CGCCCCATGTAGGTACGCCCCACGCAGGTTAGCCCT
>18.23|2823193|35|NZ_CP021983|CRISPRCasFinder,CRT
CGACCCTGTGGGCCGACTGTGGTTGGCCTGTAGAG
>18.24|2823265|36|NZ_CP021983|CRISPRCasFinder,CRT
AGATCCCTTATCCCGATGCGTCCACTCCGAACACAG
>18.25|2823338|37|NZ_CP021983|CRISPRCasFinder,CRT
CTATCCAAGCGGACGATCGATTTGCCGTTGGTGTCAG
>18.26|2823412|35|NZ_CP021983|CRISPRCasFinder,CRT
ATGCCAGAGCCTACCACCAGCAGCACCCCTGCCAA
>18.27|2823484|36|NZ_CP021983|CRISPRCasFinder,CRT
GCTAAATAACTGGCGCAAGCATTGACTTGGGATACT

CRISPR arrays and Neighbor proteins around NZ_CP021983_18

CRISPR arrays

The CRISPR arrays of NZ_CP021983_18

>merge|NZ_CP021983|18|2822496-2823556|PILER-CR,CRISPRCasFinder,CRT
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAACTTGTCCTCAGTCCGGTATTTGGCGGTTTCTGCGGCGCTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAACGCTTACTCAGAAAGGGAGGTCAAGAAGGTCCTCTTTCTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAACAGGAAAATGCAACGATATTTTGTGATTGAGCCCTTCTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAACGCGGCTAAGATGCGGCAATAGCACGACACTATGCCTACTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAACCGATCAGTCAAGGTGGTGTGGGACAACCTGCTGCCTCTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAACGCCAAGTGGCGGGGGAGTGGGGCATGGGCCAGTGAGTACTCGCCAACTTCTAAATCTCGGCAACGAGGACTGAAACCTAGCAGTGAGATATATGGTGAACGCTCCCCCCAGGCTCTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAACACAGCAAAGATGCCAGTAATGCCGTGCAGTACAGCTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAACCGCCCCATGTAGGTACGCCCCACGCAGGTTAGCCCTCTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAACCGACCCTGTGGGCCGACTGTGGTTGGCCTGTAGAGCTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAACAGATCCCTTATCCCGATGCGTCCACTCCGAACACAGCTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAACCTATCCAAGCGGACGATCGATTTGCCGTTGGTGTCAGCTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAACATGCCAGAGCCTACCACCAGCAGCACCCCTGCCAACTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAACGCTAAATAACTGGCGCAAGCATTGACTTGGGATACTCTCGCCAACTTCTAAATCTCGGCAACGGTGATCGATA

>NZ_CP021983|18|9|2822496-2823482|PILER-CR
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAA	CTTGTCCTCAGTCCGGTATTTGGCGGTTTCTGCGGCG
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAA	CGCTTACTCAGAAAGGGAGGTCAAGAAGGTCCTCTTT
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAA	CAGGAAAATGCAACGATATTTTGTGATTGAGCCCTT
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAA	CGCGGCTAAGATGCGGCAATAGCACGACACTATGCCTA
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAA	CCGATCAGTCAAGGTGGTGTGGGACAACCTGCTGCCT
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAA	CGCCAAGTGGCGGGGGAGTGGGGCATGGGCCAGTGAGTA
CTCGCCAACTTCTAAATCTCGGCAACGAGGACTGAA	ACCTAGCAGTGAGATATATGGTGAACGCTCCCCCCAGGCTCTCGCCA
ACTTCTAAATCTCGGCAACGAGACTGAAACACAGCA	AAGATGCCAGTAATGCCGTGCAGTACAGCTCGCCA
ACTTCTAAATCTCGGCAACGAGACTGAAACCGCCCC	ATGTAGGTACGCCCCACGCAGGTTAGCCCTCTCGCCA
ACTTCTAAATCTCGGCAACGAGACTGAAACCGACCC	TGTGGGCCGACTGTGGTTGGCCTGTAGAGCTCGCCA
ACTTCTAAATCTCGGCAACGAGACTGAAACAGATCC	CTTATCCCGATGCGTCCACTCCGAACACAGCTCGCCA
ACTTCTAAATCTCGGCAACGAGACTGAAACCTATCC	AAGCGGACGATCGATTTGCCGTTGGTGTCAGCTCGCCA
ACTTCTAAATCTCGGCAACGAGACTGAAACATGCCA	GAGCCTACCACCAGCAGCACCCCTGCCAACTCGCCA
ACTTCTAAATCTCGGCAACGAGACTGAAA

>NZ_CP021983|18|19|2822496-2823556|CRISPRCasFinder
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	TTGTCCTCAGTCCGGTATTTGGCGGTTTCTGCGGCG
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	GCTTACTCAGAAAGGGAGGTCAAGAAGGTCCTCTTT
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	AGGAAAATGCAACGATATTTTGTGATTGAGCCCTT
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	GCGGCTAAGATGCGGCAATAGCACGACACTATGCCTA
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	CGATCAGTCAAGGTGGTGTGGGACAACCTGCTGCCT
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	GCCAAGTGGCGGGGGAGTGGGGCATGGGCCAGTGAGTA
CTCGCCAACTTCTAAATCTCGGCAACGAGGACTGAAA	CCTAGCAGTGAGATATATGGTGAACGCTCCCCCCAGGCT
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	ACAGCAAAGATGCCAGTAATGCCGTGCAGTACAG
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	CGCCCCATGTAGGTACGCCCCACGCAGGTTAGCCCT
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	CGACCCTGTGGGCCGACTGTGGTTGGCCTGTAGAG
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	AGATCCCTTATCCCGATGCGTCCACTCCGAACACAG
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	CTATCCAAGCGGACGATCGATTTGCCGTTGGTGTCAG
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	ATGCCAGAGCCTACCACCAGCAGCACCCCTGCCAA
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	GCTAAATAACTGGCGCAAGCATTGACTTGGGATACT
CTCGCCAACTTCTAAATCTCGGCAACGGTGATCGATA

>NZ_CP021983|18|8|2822496-2823556|CRT
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	TTGTCCTCAGTCCGGTATTTGGCGGTTTCTGCGGCG
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	GCTTACTCAGAAAGGGAGGTCAAGAAGGTCCTCTTT
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	AGGAAAATGCAACGATATTTTGTGATTGAGCCCTT
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	GCGGCTAAGATGCGGCAATAGCACGACACTATGCCTA
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	CGATCAGTCAAGGTGGTGTGGGACAACCTGCTGCCT
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	GCCAAGTGGCGGGGGAGTGGGGCATGGGCCAGTGAGTA
CTCGCCAACTTCTAAATCTCGGCAACGAGGACTGAAA	CCTAGCAGTGAGATATATGGTGAACGCTCCCCCCAGGCT
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	ACAGCAAAGATGCCAGTAATGCCGTGCAGTACAG
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	CGCCCCATGTAGGTACGCCCCACGCAGGTTAGCCCT
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	CGACCCTGTGGGCCGACTGTGGTTGGCCTGTAGAG
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	AGATCCCTTATCCCGATGCGTCCACTCCGAACACAG
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	CTATCCAAGCGGACGATCGATTTGCCGTTGGTGTCAG
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	ATGCCAGAGCCTACCACCAGCAGCACCCCTGCCAA
CTCGCCAACTTCTAAATCTCGGCAACGAGACTGAAAC	GCTAAATAACTGGCGCAAGCATTGACTTGGGATACT
CTCGCCAACTTCTAAATCTCGGCAACGGTGATCGATA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_080810411.1|2818018_2818777_+|type-I-D-CRISPR-associated-protein-Cas5/Csc1	csc1gr5	cd09711_csc1gr5_CAS-I-D	gnl|CDD|274458
NZ_CP021983.1|WP_080810409.1|2818715_2819561_+|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	gnl|CDD|227838
NZ_CP021983.1|WP_088430044.1|2821990_2822287_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NZ_CP021983.1|WP_080810395.1|2829186_2829780_+|phycobiliprotein-lyase	unknown	unknown	gnl|CDD|312763
NZ_CP021983.1|WP_080810412.1|2817005_2817998_+|type-I-D-CRISPR-associated-protein-Cas7/Csc2	csc2gr7	cd09709_csc2gr7_CAS-I-D	gnl|CDD|375747
NZ_CP021983.1|WP_088431673.1|2823666_2824434_-|glycerol-acyltransferase	unknown	unknown	gnl|CDD|153249
NZ_CP021983.1|WP_080810414.1|2814018_2817003_+|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	cas10d	cd09712_cas10d_CAS-I-D	gnl|CDD|187843
NZ_CP021983.1|WP_080810408.1|2819597_2819858_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080810398.1|2826810_2827515_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080810393.1|2829793_2830330_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080810390.1|2832342_2832972_-|precorrin-8X-methylmutase	unknown	unknown	gnl|CDD|180325
NZ_CP021983.1|WP_088430038.1|2811884_2814005_+|type-I-D-CRISPR-associated-helicase-Cas3'	cas3	cd09710_cas3_CAS-I-D	gnl|CDD|187841
NZ_CP021983.1|WP_080810400.1|2826564_2826798_+|hypothetical-protein	unknown	unknown	gnl|CDD|381327
NZ_CP021983.1|WP_088430042.1|2820955_2821933_+|type-I-D-CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|274976
NZ_CP021983.1|WP_080810392.1|2831357_2831927_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NZ_CP021983.1|WP_088430040.1|2819934_2820210_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080810386.1|2834606_2834942_-|YtxH-domain-containing-protein	unknown	unknown	gnl|CDD|227313
NZ_CP021983.1|WP_088431675.1|2830366_2830945_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080810406.1|2820371_2820953_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl|CDD|187768
NZ_CP021983.1|WP_080810401.1|2824548_2826213_-|CTP-synthase	unknown	unknown	gnl|CDD|235437

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP021983.1|WP_080810411.1|2818018_2818777_+|type-I-D-CRISPR-associated-protein-Cas5/Csc1	csc1gr5	cd09711_csc1gr5_CAS-I-D	1.6e-56	185.8	0.4
NZ_CP021983.1|WP_088430042.1|2820955_2821933_+|type-I-D-CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	3e-107	353.0	0.0
NZ_CP021983.1|WP_088430044.1|2821990_2822287_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	7.5e-27	88.1	0.0
NZ_CP021983.1|WP_080810412.1|2817005_2817998_+|type-I-D-CRISPR-associated-protein-Cas7/Csc2	csc2gr7	cd09709_csc2gr7_CAS-I-D	3.5e-73	241.1	0.0
NZ_CP021983.1|WP_088430038.1|2811884_2814005_+|type-I-D-CRISPR-associated-helicase-Cas3'	cas3	cd09710_cas3_CAS-I-D	2.2e-61	202.5	0.0
NZ_CP021983.1|WP_080810409.1|2818715_2819561_+|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	7.3e-23	76.2	0.1
NZ_CP021983.1|WP_080810414.1|2814018_2817003_+|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	cas10d	cd09712_cas10d_CAS-I-D	4.9e-210	694.4	0.0
NZ_CP021983.1|WP_080810406.1|2820371_2820953_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	6.3e-34	112.4	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_080810411.1|2818018_2818777_+|type-I-D-CRISPR-associated-protein-Cas5/Csc1	gnl|CDD|274458	TIGR03159, cas_Csc1, CRISPR type I-D/CYANO-associated protein Csc1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family is a CRISPR-associated (Cas) family strictly associated with the Cyano subtype of CRISPR/Cas locus, found in several species of Cyanobacteria and several archaeal species. This family is designated Csc1 for CRISPR/Cas Subtype Cyano protein 1, as it is often the first gene upstream of the core cas genes, cas3-cas4-cas1-cas2.	1.31584e-61
NZ_CP021983.1|WP_080810409.1|2818715_2819561_+|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.42116e-17
NZ_CP021983.1|WP_088430044.1|2821990_2822287_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.35153e-28
NZ_CP021983.1|WP_080810395.1|2829186_2829780_+|phycobiliprotein-lyase	gnl|CDD|312763	pfam09367, CpeS, CpeS-like protein. This family, that includes CpeS proteins, is functionally uncharacterized.	3.57647e-94
NZ_CP021983.1|WP_080810412.1|2817005_2817998_+|type-I-D-CRISPR-associated-protein-Cas7/Csc2	gnl|CDD|375747	pfam18320, Csc2, Csc2 Crispr. The Csc2 Crispr family of proteins forms a core RNA recognition motif-like domain, flanked by three peripheral insertion domains: a lid domain, a Zinc-binding domain and a helical domain. The CRISPR-Cas system is possibly a mechanism of defence against invading pathogens and plasmids that functions analogously to the RNA interference (RNAi) systems in eukaryotes.	0
NZ_CP021983.1|WP_088431673.1|2823666_2824434_-|glycerol-acyltransferase	gnl|CDD|153249	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this suubgroup are such LPLATs as 2-acylglycerol O-acyltransferase (MGAT), and similar proteins.	7.19196e-38
NZ_CP021983.1|WP_080810414.1|2814018_2817003_+|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	gnl|CDD|187843	cd09712, Cas10d_I-D, CRISPR/Cas system-associated protein Cas10d. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain. Fused to N-terminal HD domain; signature gene for I-D subtype; also known as Csc3 family.	0
NZ_CP021983.1|WP_080810390.1|2832342_2832972_-|precorrin-8X-methylmutase	gnl|CDD|180325	PRK05953, PRK05953, Precorrin-8X methylmutase.	5.01642e-134
NZ_CP021983.1|WP_088430038.1|2811884_2814005_+|type-I-D-CRISPR-associated-helicase-Cas3'	gnl|CDD|187841	cd09710, Cas3_I-D, CRISPR/Cas system-associated protein Cas3; Distinct diverged subfamily of Cas3 helicase domain. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Diverged DNA helicase Cas3'; signature gene for Type I and subtype I-D.	7.25612e-53
NZ_CP021983.1|WP_080810400.1|2826564_2826798_+|hypothetical-protein	gnl|CDD|381327	cd19101, AKR_unchar, uncharacterized aldo-keto reductase (AKR) superfamily protein. This family includes a group of uncharacterized AKR superfamily proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance in both health and industrial applications.	2.26942e-19
NZ_CP021983.1|WP_088430042.1|2820955_2821933_+|type-I-D-CRISPR-associated-endonuclease-Cas1	gnl|CDD|274976	TIGR04093, hypothetical_protein_L8106_25395, CRISPR-associated endonuclease Cas1, subtype CYANO. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes a clade of Cas1 limited to the CYANO subtype of CRISPR/Cas system and most often the type found there.	3.85607e-148
NZ_CP021983.1|WP_080810392.1|2831357_2831927_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	8.56417e-24
NZ_CP021983.1|WP_080810386.1|2834606_2834942_-|YtxH-domain-containing-protein	gnl|CDD|227313	COG4980, GvpP, Gas vesicle protein [General function prediction only].	1.46801e-21
NZ_CP021983.1|WP_080810406.1|2820371_2820953_+|CRISPR-associated-protein-Cas4	gnl|CDD|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	2.43967e-33
NZ_CP021983.1|WP_080810401.1|2824548_2826213_-|CTP-synthase	gnl|CDD|235437	PRK05380, pyrG, CTP synthetase; Validated.	0

Protein sequences

>NZ_CP021983.1|WP_088430044.1|2821990_2822287_+|CRISPR-associated-endonuclease-Cas2
MAIKLLYLIIYDLPDDKAANKRRNRLHKMLSGYGEWTQYSVFECFLTATQFARLQIQIERLIKPETDSVRIYILDTGAIKRTLVYGSKRPRQPEAIIL
>NZ_CP021983.1|WP_088430042.1|2820955_2821933_+|type-I-D-CRISPR-associated-endonuclease-Cas1
MTTLYVTQPDAVLSKKYEAFAVALRQEDGSWQKRSVPAQTVEQVILMGNPQITGDALTYALELGLPVHYLTSFGKYLGSALPGHSRNGQLRLAQYALHIDPDRRLALVQAIVEAKIHNQFSVLYRHGQSDNPLKHRKKATRKQKTLDKVRGIEGMAAREYFACWPAMLKQDWGFTGRNRRPARDPVNALLSFAYALLQVQVTAAIHLAGLDPYVGYLHEVHHGQPALVLDVMEEFRPLIADNLVLAVINNREIQPQDFTESLGAYTLSDRGRKTFLQAFERKMTDEFKHPVFDYRCTYRRAVELQARLLSRHLQEAIPYKPLMLR
>NZ_CP021983.1|WP_080810406.1|2820371_2820953_+|CRISPR-associated-protein-Cas4
MQDDYLPLAYLNAWEYCPRRFYLEYQLGEMADNEHIILGRHLHRVVDDEGQQYDGDILTRRHQWVWSDRLRVKGVIDLVEQQGDQLIPVEFKKGAMGRHLSDHFQLCAAGLCLEERTQQPITHGEIFYHSNRRRQHVPFTPELRQATEDAILAAHDSLNAPIPKPITNKRKCQACSLQGICLPFEVNLLRETT
>NZ_CP021983.1|WP_088430040.1|2819934_2820210_+|hypothetical-protein
MRKATIVRATRDRQLEISPEIQAQLNRGDEYLIWQSGDSIHLQKIHKPSSFEDLMARVDALGPDPDQLNMEEITNLVKEVRRDMQQSNHQE
>NZ_CP021983.1|WP_080810408.1|2819597_2819858_+|hypothetical-protein
MTIQDLIATLSQFDPNTPVVISGYEGGYNDVSVVRPLEIQLNVNNKHYYGAHHCVKGTLVPDVPLTSVVYLGGFNPISDAPELSYH
>NZ_CP021983.1|WP_080810409.1|2818715_2819561_+|CRISPR-associated-endoribonuclease-Cas6
MKPAYPLAVTTGQDIWPTPHRSTSLYSIVVQLAAAGQGRFPATLGRAIHSQVLTWLQAGDSSVAQAVHSTQVSPMSLSGLVGRRRKQGTRPDDEFYFRIGLLNGDLLEPLLAGLDTWGTQPISLGNFPFVLRGVEALPGEHKQVQIGNYHLLSKTSPVSDDLSLELRSPTAFKQGKKTIQPFPLPELVFGSLLRRWNAFAPEDLQFSQIEWQGMVSAFDLKTRVLRLEGGPQIGSVGWIRYRFLDAEQARIASVLAQYAFFAGVGYKTTMGMGQVQSLNHA
>NZ_CP021983.1|WP_080810411.1|2818018_2818777_+|type-I-D-CRISPR-associated-protein-Cas5/Csc1
MLYQCDLTLHDNVFFATREMGTLFETEKYLHNWALSYALFEGQYLNRPYRLQGEYAQKPNYLDSSHEQSLHPLNETGIYVFPAQPLQWAYQVNTFKAAQVNYYGKSKQFGDKGADRNYPINFGRAKELAVGSTYRTYIMAKDQATLPDWLQQKDDDKRRTWIRLGKWAAKIHIQAKSIAGETTGSGTFICRHPLNPLDLAVSIRLMVYNRIVMPPVSLVSQAQLEGEYWRLPDETCLPIGCYYGARYMANAS
>NZ_CP021983.1|WP_080810412.1|2817005_2817998_+|type-I-D-CRISPR-associated-protein-Cas7/Csc2
MTILESLKPEFHSTFPRLASGKYVHFLMVRHSQSFPVFQTDGVLNVARTKAGLDTTDKFSRLVMFKRKQTTPERLAGRELLRSLGLTTADKENKERFCEYNGEGSCKKCPDCIIYGFAIGDSGSERSKVYSDSAFSLSPYEQSHKSFTFNAPFEGGTMSEAGEMRSAINELDHILPEVNFPTVETLRDPTYEGFIYVLGNLLRTRRYGAQESRTGTMTNHLIGIAFADGEIFSNLYFTQALYDALKNDLDAPIDEVRNKAQEVAAILLAQEPVRKTQQIFGEQLDSLLAEVTAIYQDEAQSQTVLSILYQQTQTYAETYGANSGKKGRRK
>NZ_CP021983.1|WP_080810414.1|2814018_2817003_+|type-I-D-CRISPR-associated-protein-Cas10d/Csc3
MTLLQDLLTTTLQEEPDPVIQRFVETVVPAMEQEFALVPALGGSDAVHRYRLRDDPFCEEKVQRWNQSADQSLLVHVINAILTAWNLQTFLDEDKQLTEEEKKLLCLGLTLHDYNKYCQGEEEDAPKTHEVSEILGLCHKLGHKLNFTDFWQDWENYLGDIGFLAQNTQYKTGTNPRLEVWNPKITDQRRLKNPLRPLLAFGDIAVHMNDPADIVTPKEGNQSRSRGHALREHLETLQIERKLVYHRLRDCTGLLTTGIHNAVLHFTEDLDWKPILFFAQGVVYLAPLDSETPDRETIQAVLWEQIQQLLANKMLSGDIGFKRDGKGLKVAPQTLEVFKPAQLIRGLPDVIIAKVGNAKNPATPKRLASLELSDTECQKLEPAADLRSDRLAELIFLAQKEFFGACPDFVPWVLKYLGIEQGISPEQTQVQSGGVNYGWYRAAAYYIAVTQKNTLDNEELEKILENLAYSLADWAEENDLLPEYKSPTQDVFHRYLNQNLEVSGWEPCLTSFDDELSAYTAAKTKASKQPICSLSSGEFASEDQMDSVVLFKPQQYSNKNPLGGRHIKRGISKIWSLEMLIRQAMWAVPAGKLEDQRPVFLYIFPAYVYSPQTAKVVRVLMDELKDRINFWDIRKFWQENNMDIQALRSYSWLEEESEAGRFGNPNYGRGDRRDLPFVAITYTTTRGKTVTDAWIEPAFLAMALPMLLGVKVVASTSPAPLYSSDSEFRESVKLDGPAGFWNSLGLPNSLHLEEWLQNRVQRLDELLNRLMIAYALHLDCEGDPPDPRWRAFANTVRDMMTDVLNIFSLAASHFRELKREPYPDEVGRYWRYAQIWTEGNTNMQKKLKITKQLVTEYRKFYRVNLSESSHAILLPLSKALELILSVPEDWDDEELILQGSGQLQDALDRQKVYRPILSDKSLPYQERKVQELEAIQAFVTTCVKDLFGEMCKGDRALLQENRNRIKSGVEFAYRWLTLQESQAETKNQKTEGEK
>NZ_CP021983.1|WP_088430038.1|2811884_2814005_+|type-I-D-CRISPR-associated-helicase-Cas3'
MKVFLKPLYSKLNDGPGNCPLGCQEKCRVAENSDLKPLKGQSCALSLHQALTWEAVVQGDTDVIFNTAATGDGKSLAATLPILLNKNLRMVGMYPTIELVDDQDRSHRDSDTRKGWHSTFGLNAEKRIDRLYGEELSRRVRDGESNRFQELRKAIENKPLILTNPDIFHLITHFQYKNPAYGDFELPLLMAEFPDFWLFDEFHIFGPHQESAVINSMGFIRRSQRRKRRFLFTSATPKDSFVKQLKAADFGEPKIIPGNYSDHPQDGYRKILEPVELEFMQLKKQDVLEWLQGKYHEVYEWLANEQRGRGLIILNSVAQAGRVVDLLKGLFQNSVEVEEISGRMDRASRQVTQEKLKHSRKPVLVIGTSAVDVGVDFKIHLLIFESSDSATVIQRLGRLGRHEGFKHYRAIALLPEYASWILGKLKKQLTEGASVDREELRDTIIDAFDAPKEFQEYRREWGVVQAQGMLSQLKAKEYAKVMQPVYERIAKDLQPLYGSNIIGFAQRKLRDYDKSVAEAIQTELIRFRGGTSIQAAVWDENRFYTYDLLRLLPYTLVEVLDEAEFLEAAYRRGYRDYTFQYAQVFLKVQRWVDERIDIQLRTGRDSSELQCCDLILLGKLRLSQHPQADVINCMSRKKFLSFLVPGDYWKVRDALRVGPLFGLYPLLDSSEKSYACAFGQDALLLKALRNGRLSKLCRQNSAPMFF
>NZ_CP021983.1|WP_088431673.1|2823666_2824434_-|glycerol-acyltransferase
MMRLWRWLYQYYFRVDTDGWQHIPQDGPLLFVGSHNGGLATPDLPMFMYDWYRRFGLEQPIYGLMHPKVWQIFPKTAQVAASLGAIRAHPKMAIAALAQGAHVLVYPGGAQDSFRPHRLRHRIHLAGRTGFIKLALRQGATIVPLVSWGAHDSLIVLEDCYDQAKYLHRLGMPWLFNTDPEVFPIYLGLPWGVSLGALPNIPLPVQIHTRVGQPIRFPHYGRDTLRDRTYVMACHDIVVTQMQALLDTLAREVAT
>NZ_CP021983.1|WP_080810401.1|2824548_2826213_-|CTP-synthase
MTKFVFVTGGVVSSIGKGIVAASLGRLLKSRDYSVSILKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFTDTAMSRLNSVTTGSIYQAVINKERRGDYQGGTVQVIPHITNEIKERVHRVARNTSPDVVITEIGGTVGDIESLPFLEAIRQFRKDVGRRDVLYMHVTLVPWIASAGELKTKPTQHSVKELRSIGIQPDILVCRCERPVPDYIKEKISEFCDVPAGCVITSQDANSIYEVPLNLEQEGLAHQVLDILQLPQRQPDLTHWRALVDGLYSSTKPVEIAIVGKYVSLNDAYLSVVESLRHAAIAHKAALRVCWVNSEDIEIYGPERYLSGMDGVVVPGGFGTRGVGGKIRAIQYIREQKIPFLGLCLGMQCSVVEWARHVVHLEHANSSEFEPNTPNPVISLLPEQQDVVDLGGTMRLGLYPCRLQPDTLAQQLYQKEVIYERHRHRYEFNNAYRNLFVDSGYVISGTSPDGRLVEMIELPDHPFFIASQFHPEFQSRPSTPHPLFLGFVRAALEQPSAASPAATDAATVEVTPADAMV
>NZ_CP021983.1|WP_080810400.1|2826564_2826798_+|hypothetical-protein
MANVAVRYVLEQPTVAGAIVGARLSIAEHIIAEHIEDNSRVFDFALTDSDQARLQAACQGSHDLFQLIGDCGDEYRR
>NZ_CP021983.1|WP_080810398.1|2826810_2827515_+|hypothetical-protein
MIAAMPPVRSRPLLYLVCSLALIITLVLAKGGIAWVSESYIYSLPMIGGLFKSLEVLELSNIIIFALLGLGLGAATVYLSHRTPIALRGLLLVLAIPIVFSASYWVRQTLWIQAVSETANIPHQQAVQLTNQVLRQETGTAGFIGFFRYTTRVPLLPTSPSELQQLAEDERWLRSELTRFSGVEPGIFSMAFESAGWGIRGFYMLLALLTAVIYFVKGQTWAEAARLRRASRRS
>NZ_CP021983.1|WP_080810395.1|2829186_2829780_+|phycobiliprotein-lyase
MEAMDFFRLSEGHWRSQRTTHHLPFRRAELGMLQIEAQALEADDPKVVEICQLHEIDPSLAIGGASVQWQGSMAWDQDDNGHSGSTILALVPDEQQPHQGSLLRERGYAEIVPVVGRYEVDEQDGLVLITEYETMSSIERFWFPNANLRLRTSTVKRFGGFSTASFCAETRLDLPASRDESAPATDLQSQFYSVMGW
>NZ_CP021983.1|WP_080810393.1|2829793_2830330_+|hypothetical-protein
MDWALRGTDYLATLRQWAYRSDMIELRGELRQRLQMCEWIGHNIHRVNQHLNQLLADCQACFHPQARPPVHILAAPLAERMSLDGFCNLSSQPITLFIDVGCLIPDDWLGVIAHEYTHAVLRSPGHDQGFGRVLSHLCLGLGLPVPPSDALESGRLAVWPRHHTKADPADFWQGNTMY
>NZ_CP021983.1|WP_088431675.1|2830366_2830945_-|hypothetical-protein
MLVITTGEVAQAQTTPSRSPDLFTQPQAQAQTATSLNADSNIDDTLYLNHDQVREHSLRLRETTRWNGITLPAGSVIRGQFEPIEGGLQYVATSVEVRDGQRPAREGHRTYSLTALSDPLHDVKDPRETNTGAILTDAAIGAAGGAALGEIFGDIDLLEVLGGAAAGAAVGNVTAQRVVVIEPGQVIPLHTQ
>NZ_CP021983.1|WP_080810392.1|2831357_2831927_+|pentapeptide-repeat-containing-protein
MRHAIWVVCAVVLSWLLWTPPSWAFIQDDVDLLLDTNSCPVCILNEADLSDLNLQKANLKVAVLAESNLKGTDLTKANLVLTDFTNADLSGAVLASAQMNGANLNKAKLAGADLHEAEMTQANLGNADLRNADLRGAIMLSVTLGTADLTGANLKDANLRGVNRSRARFCNTIMPDGEIENRSCPEQGS
>NZ_CP021983.1|WP_080810390.1|2832342_2832972_-|precorrin-8X-methylmutase
MEWHVTDAQSLKLIDREIGEHTLSPSEYEIVRRVIYTTADFDYATLIHFSDQALQSGAAALAARTTIIVDVPMVQVGITPEIQGTFANPVYCSMDALTRPQKGKTGTAWGIETLAHRYPEGIFVIGASQTALAALVDLIEADQVRPALVVATPASFLDAEGIKDRLKNSLIPHIRIAGRKGSAVVAAAIVNGLVDLAWQAYGQDAKSLG
>NZ_CP021983.1|WP_080810386.1|2834606_2834942_-|YtxH-domain-containing-protein
MANNSASFLGGMLLGTALGTAAGLLAAPRTGRETRHLLRKSADALPELVEDLSSTLQLQADRLSETTLKNWDHTLDRLRDAIAAGQAASRATYDSLTQSERSLSAESPSQE

Crispr_ID: NZ_CP021983_19

• CRISPR_ID: NZ_CP021983_19
• CRISPR_location: 2828011-2828403
• CRISPR_type: TypeI-D
• Repeat_type: NA
• Spacer_info: 5 spacers
• Cas_protein_info: cas2,cas1,cas4,cas6

Consensus repeat of NZ_CP021983_19

Consensus_repeat	Method
CTTCCCACTCAGT-GGGAAACTAATTGAATGGAAAC	PILER-CR
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	CRISPRCasFinder
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	CRT

spacers of NZ_CP021983_19

>19.1|2828046|35|NZ_CP021983|PILER-CR,CRISPRCasFinder,CRT
CAAAAGCCCACTCCACGTGTAGGATCTACCCACCC
>19.2|2828116|38|NZ_CP021983|PILER-CR,CRISPRCasFinder,CRT
CTGCCAGCTTGTGCTGGTATGTGTGGTGAAGTAGAAGT
>19.3|2828189|37|NZ_CP021983|PILER-CR,CRISPRCasFinder,CRT
ACCTCAACGGGTACTAAAGCCCCGTCAACAACGGCTG
>19.4|2828261|37|NZ_CP021983|PILER-CR,CRISPRCasFinder,CRT
TGTACACGTTGAGACGACGCCTCGGTAGGTGGCGAAT
>19.5|2828333|36|NZ_CP021983|PILER-CR,CRISPRCasFinder,CRT
CCTCGCTCTACCCTGGAGTTGTAATTTCTCCAAAAA

CRISPR arrays and Neighbor proteins around NZ_CP021983_19

CRISPR arrays

The CRISPR arrays of NZ_CP021983_19

>merge|NZ_CP021983|19|2828011-2828403|PILER-CR,CRISPRCasFinder,CRT
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAACCAAAAGCCCACTCCACGTGTAGGATCTACCCACCCCTTCCCACTCAGTGGGAAACTAATTGAATGGAAACCTGCCAGCTTGTGCTGGTATGTGTGGTGAAGTAGAAGTCTTCCCACTCAGTGGGAAACTAATTGAATGGAAACACCTCAACGGGTACTAAAGCCCCGTCAACAACGGCTGCTTCCCACTCAGTGGGAAACTAATTGAATGGAAACTGTACACGTTGAGACGACGCCTCGGTAGGTGGCGAATCTTCCCACTCAGTGGGAAACTAATTGAATGGAAACCCTCGCTCTACCCTGGAGTTGTAATTTCTCCAAAAACTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC

>NZ_CP021983|19|10|2828011-2828403|PILER-CR
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	CAAAAGCCCACTCCACGTGTAGGATCTACCCACCC
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	CTGCCAGCTTGTGCTGGTATGTGTGGTGAAGTAGAAGT
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	ACCTCAACGGGTACTAAAGCCCCGTCAACAACGGCTG
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	TGTACACGTTGAGACGACGCCTCGGTAGGTGGCGAAT
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	CCTCGCTCTACCCTGGAGTTGTAATTTCTCCAAAAA
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC

>NZ_CP021983|19|20|2828011-2828403|CRISPRCasFinder
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	CAAAAGCCCACTCCACGTGTAGGATCTACCCACCC
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	CTGCCAGCTTGTGCTGGTATGTGTGGTGAAGTAGAAGT
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	ACCTCAACGGGTACTAAAGCCCCGTCAACAACGGCTG
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	TGTACACGTTGAGACGACGCCTCGGTAGGTGGCGAAT
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	CCTCGCTCTACCCTGGAGTTGTAATTTCTCCAAAAA
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC

>NZ_CP021983|19|9|2828011-2828403|CRT
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	CAAAAGCCCACTCCACGTGTAGGATCTACCCACCC
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	CTGCCAGCTTGTGCTGGTATGTGTGGTGAAGTAGAAGT
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	ACCTCAACGGGTACTAAAGCCCCGTCAACAACGGCTG
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	TGTACACGTTGAGACGACGCCTCGGTAGGTGGCGAAT
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC	CCTCGCTCTACCCTGGAGTTGTAATTTCTCCAAAAA
CTTCCCACTCAGTGGGAAACTAATTGAATGGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_080810390.1|2832342_2832972_-|precorrin-8X-methylmutase	unknown	unknown	gnl|CDD|180325
NZ_CP021983.1|WP_080810398.1|2826810_2827515_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088430044.1|2821990_2822287_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NZ_CP021983.1|WP_080810395.1|2829186_2829780_+|phycobiliprotein-lyase	unknown	unknown	gnl|CDD|312763
NZ_CP021983.1|WP_088431673.1|2823666_2824434_-|glycerol-acyltransferase	unknown	unknown	gnl|CDD|153249
NZ_CP021983.1|WP_080810401.1|2824548_2826213_-|CTP-synthase	unknown	unknown	gnl|CDD|235437
NZ_CP021983.1|WP_080810408.1|2819597_2819858_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080810384.1|2835023_2835353_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088431675.1|2830366_2830945_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080810393.1|2829793_2830330_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088430046.1|2835539_2837741_+|DUF1565-domain-containing-protein	unknown	unknown	gnl|CDD|284923
NZ_CP021983.1|WP_080810400.1|2826564_2826798_+|hypothetical-protein	unknown	unknown	gnl|CDD|381327
NZ_CP021983.1|WP_088430042.1|2820955_2821933_+|type-I-D-CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|274976
NZ_CP021983.1|WP_080810392.1|2831357_2831927_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NZ_CP021983.1|WP_080810378.1|2838401_2838737_+|photosystem-II-reaction-center-protein-Psb28	unknown	unknown	gnl|CDD|237446
NZ_CP021983.1|WP_088430040.1|2819934_2820210_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080810409.1|2818715_2819561_+|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	gnl|CDD|227838
NZ_CP021983.1|WP_088430048.1|2838753_2839251_+|molybdenum-cofactor-biosynthesis-protein	unknown	unknown	gnl|CDD|238451
NZ_CP021983.1|WP_080810406.1|2820371_2820953_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl|CDD|187768
NZ_CP021983.1|WP_080810386.1|2834606_2834942_-|YtxH-domain-containing-protein	unknown	unknown	gnl|CDD|227313

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP021983.1|WP_088430042.1|2820955_2821933_+|type-I-D-CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	3e-107	353.0	0.0
NZ_CP021983.1|WP_088430044.1|2821990_2822287_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	7.5e-27	88.1	0.0
NZ_CP021983.1|WP_080810406.1|2820371_2820953_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	6.3e-34	112.4	0.0
NZ_CP021983.1|WP_080810409.1|2818715_2819561_+|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	7.3e-23	76.2	0.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_080810401.1|2824548_2826213_-|CTP-synthase	gnl|CDD|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP021983.1|WP_088430044.1|2821990_2822287_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.35153e-28
NZ_CP021983.1|WP_080810395.1|2829186_2829780_+|phycobiliprotein-lyase	gnl|CDD|312763	pfam09367, CpeS, CpeS-like protein. This family, that includes CpeS proteins, is functionally uncharacterized.	3.57647e-94
NZ_CP021983.1|WP_088431673.1|2823666_2824434_-|glycerol-acyltransferase	gnl|CDD|153249	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this suubgroup are such LPLATs as 2-acylglycerol O-acyltransferase (MGAT), and similar proteins.	7.19196e-38
NZ_CP021983.1|WP_080810409.1|2818715_2819561_+|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.42116e-17
NZ_CP021983.1|WP_088430048.1|2838753_2839251_+|molybdenum-cofactor-biosynthesis-protein	gnl|CDD|238451	cd00886, MogA_MoaB, MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea, and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MogA, together with MoeA, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes. In contrast, MoaB shows high similarity to MogA, but little is known about its physiological role. All well studied members of this family form highly stable trimers.	9.55108e-64
NZ_CP021983.1|WP_080810390.1|2832342_2832972_-|precorrin-8X-methylmutase	gnl|CDD|180325	PRK05953, PRK05953, Precorrin-8X methylmutase.	5.01642e-134
NZ_CP021983.1|WP_088430046.1|2835539_2837741_+|DUF1565-domain-containing-protein	gnl|CDD|284923	pfam07602, DUF1565, Protein of unknown function (DUF1565). These proteins share a region of homology in their N termini, and are found in several phylogenetically diverse bacteria and in the archaeon Methanosarcina acetivorans. Some of these proteins also contain characterized domains such as pfam00395 and pfam03422.	1.7552e-25
NZ_CP021983.1|WP_080810400.1|2826564_2826798_+|hypothetical-protein	gnl|CDD|381327	cd19101, AKR_unchar, uncharacterized aldo-keto reductase (AKR) superfamily protein. This family includes a group of uncharacterized AKR superfamily proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance in both health and industrial applications.	2.26942e-19
NZ_CP021983.1|WP_088430042.1|2820955_2821933_+|type-I-D-CRISPR-associated-endonuclease-Cas1	gnl|CDD|274976	TIGR04093, hypothetical_protein_L8106_25395, CRISPR-associated endonuclease Cas1, subtype CYANO. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes a clade of Cas1 limited to the CYANO subtype of CRISPR/Cas system and most often the type found there.	3.85607e-148
NZ_CP021983.1|WP_080810392.1|2831357_2831927_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	8.56417e-24
NZ_CP021983.1|WP_080810378.1|2838401_2838737_+|photosystem-II-reaction-center-protein-Psb28	gnl|CDD|237446	PRK13612, PRK13612, photosystem II reaction center protein Psb28; Provisional.	2.81196e-64
NZ_CP021983.1|WP_080810406.1|2820371_2820953_+|CRISPR-associated-protein-Cas4	gnl|CDD|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	2.43967e-33
NZ_CP021983.1|WP_080810386.1|2834606_2834942_-|YtxH-domain-containing-protein	gnl|CDD|227313	COG4980, GvpP, Gas vesicle protein [General function prediction only].	1.46801e-21

Protein sequences

>NZ_CP021983.1|WP_080810398.1|2826810_2827515_+|hypothetical-protein
MIAAMPPVRSRPLLYLVCSLALIITLVLAKGGIAWVSESYIYSLPMIGGLFKSLEVLELSNIIIFALLGLGLGAATVYLSHRTPIALRGLLLVLAIPIVFSASYWVRQTLWIQAVSETANIPHQQAVQLTNQVLRQETGTAGFIGFFRYTTRVPLLPTSPSELQQLAEDERWLRSELTRFSGVEPGIFSMAFESAGWGIRGFYMLLALLTAVIYFVKGQTWAEAARLRRASRRS
>NZ_CP021983.1|WP_080810400.1|2826564_2826798_+|hypothetical-protein
MANVAVRYVLEQPTVAGAIVGARLSIAEHIIAEHIEDNSRVFDFALTDSDQARLQAACQGSHDLFQLIGDCGDEYRR
>NZ_CP021983.1|WP_080810401.1|2824548_2826213_-|CTP-synthase
MTKFVFVTGGVVSSIGKGIVAASLGRLLKSRDYSVSILKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFTDTAMSRLNSVTTGSIYQAVINKERRGDYQGGTVQVIPHITNEIKERVHRVARNTSPDVVITEIGGTVGDIESLPFLEAIRQFRKDVGRRDVLYMHVTLVPWIASAGELKTKPTQHSVKELRSIGIQPDILVCRCERPVPDYIKEKISEFCDVPAGCVITSQDANSIYEVPLNLEQEGLAHQVLDILQLPQRQPDLTHWRALVDGLYSSTKPVEIAIVGKYVSLNDAYLSVVESLRHAAIAHKAALRVCWVNSEDIEIYGPERYLSGMDGVVVPGGFGTRGVGGKIRAIQYIREQKIPFLGLCLGMQCSVVEWARHVVHLEHANSSEFEPNTPNPVISLLPEQQDVVDLGGTMRLGLYPCRLQPDTLAQQLYQKEVIYERHRHRYEFNNAYRNLFVDSGYVISGTSPDGRLVEMIELPDHPFFIASQFHPEFQSRPSTPHPLFLGFVRAALEQPSAASPAATDAATVEVTPADAMV
>NZ_CP021983.1|WP_088431673.1|2823666_2824434_-|glycerol-acyltransferase
MMRLWRWLYQYYFRVDTDGWQHIPQDGPLLFVGSHNGGLATPDLPMFMYDWYRRFGLEQPIYGLMHPKVWQIFPKTAQVAASLGAIRAHPKMAIAALAQGAHVLVYPGGAQDSFRPHRLRHRIHLAGRTGFIKLALRQGATIVPLVSWGAHDSLIVLEDCYDQAKYLHRLGMPWLFNTDPEVFPIYLGLPWGVSLGALPNIPLPVQIHTRVGQPIRFPHYGRDTLRDRTYVMACHDIVVTQMQALLDTLAREVAT
>NZ_CP021983.1|WP_088430044.1|2821990_2822287_+|CRISPR-associated-endonuclease-Cas2
MAIKLLYLIIYDLPDDKAANKRRNRLHKMLSGYGEWTQYSVFECFLTATQFARLQIQIERLIKPETDSVRIYILDTGAIKRTLVYGSKRPRQPEAIIL
>NZ_CP021983.1|WP_088430042.1|2820955_2821933_+|type-I-D-CRISPR-associated-endonuclease-Cas1
MTTLYVTQPDAVLSKKYEAFAVALRQEDGSWQKRSVPAQTVEQVILMGNPQITGDALTYALELGLPVHYLTSFGKYLGSALPGHSRNGQLRLAQYALHIDPDRRLALVQAIVEAKIHNQFSVLYRHGQSDNPLKHRKKATRKQKTLDKVRGIEGMAAREYFACWPAMLKQDWGFTGRNRRPARDPVNALLSFAYALLQVQVTAAIHLAGLDPYVGYLHEVHHGQPALVLDVMEEFRPLIADNLVLAVINNREIQPQDFTESLGAYTLSDRGRKTFLQAFERKMTDEFKHPVFDYRCTYRRAVELQARLLSRHLQEAIPYKPLMLR
>NZ_CP021983.1|WP_080810406.1|2820371_2820953_+|CRISPR-associated-protein-Cas4
MQDDYLPLAYLNAWEYCPRRFYLEYQLGEMADNEHIILGRHLHRVVDDEGQQYDGDILTRRHQWVWSDRLRVKGVIDLVEQQGDQLIPVEFKKGAMGRHLSDHFQLCAAGLCLEERTQQPITHGEIFYHSNRRRQHVPFTPELRQATEDAILAAHDSLNAPIPKPITNKRKCQACSLQGICLPFEVNLLRETT
>NZ_CP021983.1|WP_088430040.1|2819934_2820210_+|hypothetical-protein
MRKATIVRATRDRQLEISPEIQAQLNRGDEYLIWQSGDSIHLQKIHKPSSFEDLMARVDALGPDPDQLNMEEITNLVKEVRRDMQQSNHQE
>NZ_CP021983.1|WP_080810408.1|2819597_2819858_+|hypothetical-protein
MTIQDLIATLSQFDPNTPVVISGYEGGYNDVSVVRPLEIQLNVNNKHYYGAHHCVKGTLVPDVPLTSVVYLGGFNPISDAPELSYH
>NZ_CP021983.1|WP_080810409.1|2818715_2819561_+|CRISPR-associated-endoribonuclease-Cas6
MKPAYPLAVTTGQDIWPTPHRSTSLYSIVVQLAAAGQGRFPATLGRAIHSQVLTWLQAGDSSVAQAVHSTQVSPMSLSGLVGRRRKQGTRPDDEFYFRIGLLNGDLLEPLLAGLDTWGTQPISLGNFPFVLRGVEALPGEHKQVQIGNYHLLSKTSPVSDDLSLELRSPTAFKQGKKTIQPFPLPELVFGSLLRRWNAFAPEDLQFSQIEWQGMVSAFDLKTRVLRLEGGPQIGSVGWIRYRFLDAEQARIASVLAQYAFFAGVGYKTTMGMGQVQSLNHA
>NZ_CP021983.1|WP_080810395.1|2829186_2829780_+|phycobiliprotein-lyase
MEAMDFFRLSEGHWRSQRTTHHLPFRRAELGMLQIEAQALEADDPKVVEICQLHEIDPSLAIGGASVQWQGSMAWDQDDNGHSGSTILALVPDEQQPHQGSLLRERGYAEIVPVVGRYEVDEQDGLVLITEYETMSSIERFWFPNANLRLRTSTVKRFGGFSTASFCAETRLDLPASRDESAPATDLQSQFYSVMGW
>NZ_CP021983.1|WP_080810393.1|2829793_2830330_+|hypothetical-protein
MDWALRGTDYLATLRQWAYRSDMIELRGELRQRLQMCEWIGHNIHRVNQHLNQLLADCQACFHPQARPPVHILAAPLAERMSLDGFCNLSSQPITLFIDVGCLIPDDWLGVIAHEYTHAVLRSPGHDQGFGRVLSHLCLGLGLPVPPSDALESGRLAVWPRHHTKADPADFWQGNTMY
>NZ_CP021983.1|WP_088431675.1|2830366_2830945_-|hypothetical-protein
MLVITTGEVAQAQTTPSRSPDLFTQPQAQAQTATSLNADSNIDDTLYLNHDQVREHSLRLRETTRWNGITLPAGSVIRGQFEPIEGGLQYVATSVEVRDGQRPAREGHRTYSLTALSDPLHDVKDPRETNTGAILTDAAIGAAGGAALGEIFGDIDLLEVLGGAAAGAAVGNVTAQRVVVIEPGQVIPLHTQ
>NZ_CP021983.1|WP_080810392.1|2831357_2831927_+|pentapeptide-repeat-containing-protein
MRHAIWVVCAVVLSWLLWTPPSWAFIQDDVDLLLDTNSCPVCILNEADLSDLNLQKANLKVAVLAESNLKGTDLTKANLVLTDFTNADLSGAVLASAQMNGANLNKAKLAGADLHEAEMTQANLGNADLRNADLRGAIMLSVTLGTADLTGANLKDANLRGVNRSRARFCNTIMPDGEIENRSCPEQGS
>NZ_CP021983.1|WP_080810390.1|2832342_2832972_-|precorrin-8X-methylmutase
MEWHVTDAQSLKLIDREIGEHTLSPSEYEIVRRVIYTTADFDYATLIHFSDQALQSGAAALAARTTIIVDVPMVQVGITPEIQGTFANPVYCSMDALTRPQKGKTGTAWGIETLAHRYPEGIFVIGASQTALAALVDLIEADQVRPALVVATPASFLDAEGIKDRLKNSLIPHIRIAGRKGSAVVAAAIVNGLVDLAWQAYGQDAKSLG
>NZ_CP021983.1|WP_080810386.1|2834606_2834942_-|YtxH-domain-containing-protein
MANNSASFLGGMLLGTALGTAAGLLAAPRTGRETRHLLRKSADALPELVEDLSSTLQLQADRLSETTLKNWDHTLDRLRDAIAAGQAASRATYDSLTQSERSLSAESPSQE
>NZ_CP021983.1|WP_080810384.1|2835023_2835353_-|hypothetical-protein
MAGETGDMVVLVVVGLNLAIATAGFYLAWRLWRLRLHLSRLADLLLAWQQDSQRHLRETPLHLGRQGTARLRQQYAQLQQQVLLIRRLVSIMGWLAAILRRRQRLGRSS
>NZ_CP021983.1|WP_088430046.1|2835539_2837741_+|DUF1565-domain-containing-protein
MQVNPASGRDDRPGGPYQTLAHALQQATAGTLIQLAAGTYSQASGERFPLLVPDGVLLLGDESTQGTAIVIHGGGPHHSPSQGEQTVTLILAGSAQLRGVTVTNPRAGGIGLWIEQGAPLVSRCRLRQCGHGGGQILAQARPTIVDTLIEANGTVGLQWQGHAKGEVQRCQCRQSGQALSILGAAAPLLSALHCSGNRVGCRIGATARPVLRQTRLDNNEIGLWVDAEALPDLGHPQDDGGNVWRHNRQADLRNDTARRLQSVGNDVVPQGLVGAVALVASQRPDPVAVPPPLGQAPPTPDSPPASPAPPPATPSPQGSRFRDMAGHWAAPFVEGLAQRGLVKGFIDGRFRPDQQVTRAQFAALTVASFANNATTTRKTSAPFQDLPPQHWAAAAIATAQDQGFLSGYPDGTVRPDQPMTRVQALVALANGLGLPSTAIPVTYRDRAQIPSYAVGPVAAATQQGLVVNYPHPQELRPMAPITSAEVAALVYQGLVNQGQATVMTSPYVVAATADWPRFTDVAHHWAAAFIEPLADRGLIQGYADGRFQPDQPMTRAQFAAMLTQAFHPISPATARGFPGRAPRLLGADAIQTAYRAGFMAGFPDHTFGPNHPLLRVQVLVSLVNGLFSAAATADSQQWQHYQDADAIPAYARQAIAQATGLGLVVTHSRSTAMPPQPRCQPGRGGRHGASSPGSPGAPGPGGVSLYCHSHWRRRIGERWAYRVVGGVRVSQAT
>NZ_CP021983.1|WP_080810378.1|2838401_2838737_+|photosystem-II-reaction-center-protein-Psb28
MAEIQFARGIKEEAVPDVRMTRSPDGTNGTATFYFDHPKALSVEEGVEVTGMYLIDEEGELVSREVNARFVNGEPTGIEATYIIRSLEEWDRFMRFMNRYAEENGLGFTKS
>NZ_CP021983.1|WP_088430048.1|2838753_2839251_+|molybdenum-cofactor-biosynthesis-protein
MVPLSEAGQPRSVGCGVITASDTRTPETDSSGQLIQDRLTTAGHRVGSYHLVADEPEQIRPLVLSLAQRPDLQVLIITGGTGIAPRDVTYDAIATLITKTLPGFGELFRYLSYLEIGSRAMASRAVAGVCENTLIFSLPGSTKAVRLAMDELILPELRHLTSLLQ

Crispr_ID: NZ_CP021983_20

• CRISPR_ID: NZ_CP021983_20
• CRISPR_location: 2878020-2878091
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP021983_20

Consensus_repeat	Method
GTGATGGGGTGTTGGGGTGATGGG	CRISPRCasFinder

spacers of NZ_CP021983_20

>20.1|2878044|24|NZ_CP021983|CRISPRCasFinder
GTGTTGGCGGAGCCTGCGCGGAGC

CRISPR arrays and Neighbor proteins around NZ_CP021983_20

CRISPR arrays

The CRISPR arrays of NZ_CP021983_20

>merge|NZ_CP021983|20|2878020-2878091|CRISPRCasFinder
GTGATGGGGTGTTGGGGTGATGGGGTGTTGGCGGAGCCTGCGCGGAGCGCATAGGGGTGATGGGGTGATGGG

>NZ_CP021983|20|21|2878020-2878091|CRISPRCasFinder
GTGATGGGGTGTTGGGGTGATGGG	GTGTTGGCGGAGCCTGCGCGGAGC
GCATAGGGGTGATGGGGTGATGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_080810344.1|2868369_2868669_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|223687
NZ_CP021983.1|WP_088430063.1|2874262_2876890_-|TonB-dependent-siderophore-receptor	unknown	unknown	gnl|CDD|273805
NZ_CP021983.1|WP_080810335.1|2873183_2874206_-|iron-siderophore-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|238566
NZ_CP021983.1|WP_088430065.1|2877393_2877975_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NZ_CP021983.1|WP_080812095.1|2882828_2883704_+|EfeM/EfeO-family-lipoprotein	unknown	unknown	gnl|CDD|271139
NZ_CP021983.1|WP_080812093.1|2881502_2882456_-|AraC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225117
NZ_CP021983.1|WP_080810337.1|2872082_2873090_-|sucrase-ferredoxin	unknown	unknown	gnl|CDD|227101
NZ_CP021983.1|WP_088430067.1|2878235_2879195_-|AraC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225117
NZ_CP021983.1|WP_080810348.1|2867707_2867929_-|DUF2281-domain-containing-protein	unknown	unknown	gnl|CDD|378366
NZ_CP021983.1|WP_080812085.1|2879451_2880186_-|hypothetical-protein	unknown	unknown	gnl|CDD|99749
NZ_CP021983.1|WP_080812091.1|2881179_2881455_-|DUF1636-domain-containing-protein	unknown	unknown	gnl|CDD|377928
NZ_CP021983.1|WP_080810346.1|2867992_2868364_-|DUF1636-domain-containing-protein	unknown	unknown	gnl|CDD|377928
NZ_CP021983.1|WP_088430073.1|2887194_2887512_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080810415.1|2869965_2870514_+|transposase	unknown	unknown	gnl|CDD|224854
NZ_CP021983.1|WP_080812089.1|2880826_2881147_-|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|143393
NZ_CP021983.1|WP_088430071.1|2885147_2886986_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NZ_CP021983.1|WP_080810416.1|2868814_2869348_+|DDE-transposase-family-protein	unknown	unknown	gnl|CDD|379382
NZ_CP021983.1|WP_080812087.1|2880498_2880834_-|HEPN-domain-containing-protein	unknown	unknown	gnl|CDD|368314
NZ_CP021983.1|WP_088430069.1|2883891_2884536_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NZ_CP021983.1|WP_080810342.1|2869307_2869880_+|hypothetical-protein	unknown	unknown	gnl|CDD|227720

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_080810344.1|2868369_2868669_-|ABC-transporter-substrate-binding-protein	gnl|CDD|223687	COG0614, FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism].	1.52156e-10
NZ_CP021983.1|WP_088430063.1|2874262_2876890_-|TonB-dependent-siderophore-receptor	gnl|CDD|273805	TIGR01783, Ferrienterobactin_receptor, TonB-dependent siderophore receptor. This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	5.97123e-90
NZ_CP021983.1|WP_080810335.1|2873183_2874206_-|iron-siderophore-ABC-transporter-substrate-binding-protein	gnl|CDD|238566	cd01146, FhuD, Fe3+-siderophore binding domain FhuD. These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA-like protein is comprised of two globular subdomains connected by a long alpha helix and binds its specific ligands in the cleft between these domains.	1.79905e-76
NZ_CP021983.1|WP_088430065.1|2877393_2877975_-|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	3.77076e-29
NZ_CP021983.1|WP_080812095.1|2882828_2883704_+|EfeM/EfeO-family-lipoprotein	gnl|CDD|271139	cd14656, Imelysin-like_EfeO, EfeO is a component of the EfeUOB operon. This family includes the EfeO domain, an essential component of the EfeUOB operon which is highly conserved in bacteria. However, its biochemical function is unknown. EfeO contains an N-terminal cupredoxin (CUP)-like domain and C-terminal imelysin-like domain that may bind iron. Algp7, a member of EfeO family protein from Sphingomonas sp. A1, is found to bind alginate at neutral pH, but does not contain the CUP domain, thus having a role that does not seem to be related to iron uptake. Some members of this family are fused to an N-terminal putative EfeU ion permease domain. The imelysin-like domain of this family also contains the GxHxxE sequence motif and a highly conserved functional site, suggesting a similar role to other imelysin family proteins containing the same motif.	6.0479e-54
NZ_CP021983.1|WP_080812093.1|2881502_2882456_-|AraC-family-transcriptional-regulator	gnl|CDD|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.66015e-26
NZ_CP021983.1|WP_080810337.1|2872082_2873090_-|sucrase-ferredoxin	gnl|CDD|227101	COG4759, COG4759, Uncharacterized protein conserved in bacteria containing thioredoxin-like domain [Posttranslational modification, protein turnover, chaperones].	1.41771e-131
NZ_CP021983.1|WP_088430067.1|2878235_2879195_-|AraC-family-transcriptional-regulator	gnl|CDD|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.9268e-32
NZ_CP021983.1|WP_080810348.1|2867707_2867929_-|DUF2281-domain-containing-protein	gnl|CDD|378366	pfam10047, DUF2281, Protein of unknown function (DUF2281). Members of this family of hypothetical bacterial proteins have no known function.	4.83049e-08
NZ_CP021983.1|WP_080812085.1|2879451_2880186_-|hypothetical-protein	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	1.32024e-08
NZ_CP021983.1|WP_080812091.1|2881179_2881455_-|DUF1636-domain-containing-protein	gnl|CDD|377928	pfam07845, DUF1636, Protein of unknown function (DUF1636). The sequences featured in this family are derived from a number of hypothetical prokaryotic proteins. The region in question is approximately 130 amino acids long.	9.8538e-14
NZ_CP021983.1|WP_080810346.1|2867992_2868364_-|DUF1636-domain-containing-protein	gnl|CDD|377928	pfam07845, DUF1636, Protein of unknown function (DUF1636). The sequences featured in this family are derived from a number of hypothetical prokaryotic proteins. The region in question is approximately 130 amino acids long.	7.64447e-53
NZ_CP021983.1|WP_080810415.1|2869965_2870514_+|transposase	gnl|CDD|224854	COG1943, COG1943, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.37085e-26
NZ_CP021983.1|WP_080812089.1|2880826_2881147_-|nucleotidyltransferase-domain-containing-protein	gnl|CDD|143393	cd05403, NT_KNTase_like, Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins. S. aureus KNTase is a plasmid encoded enzyme which confers resistance to a wide range of aminoglycoside antibiotics which have a 4'- or 4''-hydroxyl group in the equatorial position, such as kanamycin A. This enzyme transfers a nucleoside monophosphate group from a nucleotide (ATP,GTP, or UTP) to the 4'-hydroxyl group of kanamycin A. This enzyme is a homodimer, having two NT active sites. The nucleotide and antibiotic binding sites of each active site include residues from each monomer. Included in this subgroup is Escherichia coli AadA5 which confers resistance to the antibiotic spectinomycin and is a putative aminoglycoside-3'-adenylyltransferase. It is part of the aadA5 cassette of a class 1 integron. This subgroup also includes Haemophilus influenzae HI0073 which forms a 2:2 heterotetramer with an unrelated protein HI0074. Structurally HI0074 is related to the substrate-binding domain of S. aureus KNTase. The genes encoding HI0073 and HI0074 form an operon. Little is known about the substrate specificity or function of two-component NTs. The characterized members of this subgroup may not be representive of the function of this subgroup. This subgroup belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, co-ordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are conserved in this subgroup.	2.15438e-15
NZ_CP021983.1|WP_088430071.1|2885147_2886986_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	8.883e-117
NZ_CP021983.1|WP_080810416.1|2868814_2869348_+|DDE-transposase-family-protein	gnl|CDD|379382	pfam13808, DDE_Tnp_1_assoc, DDE_Tnp_1-associated. This domain is frequently found N-terminal to the transposase, IS family DDE_Tnp_1, pfam01609 and its relatives.	3.04068e-18
NZ_CP021983.1|WP_080812087.1|2880498_2880834_-|HEPN-domain-containing-protein	gnl|CDD|368314	pfam05168, HEPN, HEPN domain.	1.99215e-18
NZ_CP021983.1|WP_088430069.1|2883891_2884536_-|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	6.38351e-21
NZ_CP021983.1|WP_080810342.1|2869307_2869880_+|hypothetical-protein	gnl|CDD|227720	COG5433, COG5433, Transposase [DNA replication, recombination, and repair].	7.723e-05

Protein sequences

>NZ_CP021983.1|WP_088430065.1|2877393_2877975_-|Uma2-family-endonuclease
MVQQLSARFQTFEEYLAYDDGTDRLYELFNGELIAVPPESGCNVQIANRLFLTFALRLGTDRVRGHGLELEVRGEPKNRYPDLTLIRDEHVSLLAQRNTIRLTMSPPLLVVEVVSPGELQWQRDYVAKRLQYQDVGIPEYWIVDPQAQTVLVLTLEGDTYTELGTATGEEPVPSRQLSTLDLTPSALFAAGAQ
>NZ_CP021983.1|WP_088430063.1|2874262_2876890_-|TonB-dependent-siderophore-receptor
MRSHSITGLVQCSYALASTLSLTTLVALGWAQPATGNDLGERASGQVGESNTNERGTSQIPTTPSPHHPTTPSPLSPSGRLRQHPSTPPPATTVTEWVAQIEAAIIEITGVRVESSETGLQVILETADGDLSVPTTETVGNALVAEIPNAVLALPEGDEFQATDPAAGIARVSVTAVGQDRIQVAIMGTDAPPEATVSAEAGNLVWTVVPGIAQVDDADDAIEIVVTGEQEGYRTSNATTGTRLNIPLLETPASIGVITEELIQDRAARRGEELAPYISGVIQGGQEGASGNTPQFTIRGFDVQRQTFVNGLRDNPRFLVRDLANIERIEILKGFSSLLFGPGTPGGVVNYITERPEDTPSYDISFEAGSFDFYRGEVDLTGPLTQNQNLLYRLNLAFQESNSFVPNIEDDRIFVAPALTWLTGGGGSLTLEAEYFRLEKDGTTGAKFFDGEFFFDRSFTDPRNSDINRHFRVAAYFDQPISEQWSIALSGQYFDTRRELDPSAITINVNANNELPLFVGQILDDFNQANLRGEIRGDFEIGASEHQLLAGAEYNRSETDFPLRLGSDFPIIDVANPTFDFPLPPLGDPIPINNISNDWGIYIQDFITLGRFRLLAGLRYGQFENKDGISDEVFQDDDFVAPSVGLLYMLSDSASIYGSFSQSTEPQFGETIDGEFIEPRRATQFEIGGKVNLFDNRLSLTTALFDLTQTNIAETDPIDPNFVIPVGDVRSRGVELDIAGQITDNFRVILAYTNLFEAEIIDGEPDLEGNRFLNSPRNSLGLYGEYEFTQGALNGLSLGAGLVYVGERAGDTANSFTVPSFVRVDLGAAYQVENWTFRLTIDNLFDERFIVSASDRARLPQGEPLSVTGSVSVRF
>NZ_CP021983.1|WP_080810335.1|2873183_2874206_-|iron-siderophore-ABC-transporter-substrate-binding-protein
MIDQTPSIGNLRKILSGNGCNVPGRLRHVLSAIAMFLLISACSGTFSQNSSSHQPSLPVSDCHIVKHAMGETCVPNNLQRVVVLGGLDYVLSLGIKPVGSDELEADFPHLKDKTKGIENVGSVNIPNLEKILQLKPDFILSYRDGLKENYDTLSKIAPTVIFPFEHSDKWKERLMQYAETLDRIDVAKQMITDYYARLEAFKDQMGERLNQLEVSIVRIYPNQIVVYLKDSFCGTILADAGVSRPAYQNQMGGQQDISKERIHDLDGDAMFVWTYGYNAEQAQQANSALKRLKADPLWSQLAVVKQGKVYEVPGYWIGDGPLAANAVVDDLFKYLVGEKE
>NZ_CP021983.1|WP_080810337.1|2872082_2873090_-|sucrase-ferredoxin
MTKAEILTNFCYCCEVSKANGEDPIGSAGNYDAFLFIEVPEPWPIEFWQAQPQFQPIADLATQLKKEQGLSLRAMAIAPDCQYSQPNYTRILYYRRPSEEGFVQFEKQEFVVPDEQVVTVVLALLQQPDLLPQFESSRQETEDIREMMLCTHGSYDVACGRFGYPLYRQLRSEHAANSGGKLRVWRCTHLGPHNFAPTLVDFPEGRYWGHLELEVLDLLVYRRGPVADLYDYYQGWAGLSQVEQIAEREMWMQEGWNWFHYAKVSQVLAMDESDEYYPDWAEVRIDFNSHEGRVSGTYEARVEVSGTVKTMWSSGKDKPLWEVKQYRVSRLNKVV
>NZ_CP021983.1|WP_080810415.1|2869965_2870514_+|transposase
MPDYRRPEIAGGTYFITQVTYQRQPWLCREIGRHALRTAINQVRGTRPFAIDAFVLLPDHFHCLWTLPQNDSDLSTRLRLIKTYVTRHYGTQLGLDIDVSDSRRKRKERNLWQRRFWEHLIRDDTDFAQYCDYIHYNPVHHQLCQVPTEWQFSSVHRLIIEGIYPPNWGDYPVEFGLEGRWQ
>NZ_CP021983.1|WP_080810342.1|2869307_2869880_+|hypothetical-protein
MRLAPKKNCQLILDTDNHYLGALKGNQGNLHKSVQANFIAEDSYTEVSKGHGRLEKRVVSLCTTLDNIKPWPGLKTLIRVESERHFKKGGQPHLETETRYYVASFLESAESLARRIRGYWGVENKVHHIRDVTQGEDASRIRMHQLPQIFAVARNFALNLYRSNEFANMAQAERLCKFGLDTLKAIFRMK
>NZ_CP021983.1|WP_080810416.1|2868814_2869348_+|DDE-transposase-family-protein
MPDVRQASGKRHQMALCLALFTLAVTAGNRGFLAIGDWLKSYRSELIDLFNPPKGRLPSYSTIRRVLLKLDYGQYSAALARFFGIEPLAGETLAVDGKVLRGSYQLETDNPDSPPHPAILLVSAYLVERGLILEPYQVEHKTNEIKALPEFIKQLALKGVVIAFDAISTQKKLSAHP
>NZ_CP021983.1|WP_080810344.1|2868369_2868669_-|ABC-transporter-substrate-binding-protein
MKWPCPTKSAIALVSACGGTLFQNFDADIIFVWTWGYTSEFAKDTEKLLESLKTDPLWLQLQAVKEGNVYEVPAYWMGDSILDAYAVIDDLFKYLVDDQ
>NZ_CP021983.1|WP_080810346.1|2867992_2868364_-|DUF1636-domain-containing-protein
MSKHILFICKSCNAKSEQEHTSDPSDGTKLLNQLQILHQTWPHQADLEIREVGCLWTCSSPCAVAFSAPDKATYLFTQVPATESAKALLKFGEHYLASNDGTIPWKHFPEALQSASIAKIPSV
>NZ_CP021983.1|WP_080810348.1|2867707_2867929_-|DUF2281-domain-containing-protein
MSTAETIYELVKTLPEDQANLVLVFAEFVHQRTQASDNLNNSSITTYFGILKDSPNFNEDSVAIQRAMRREWE
>NZ_CP021983.1|WP_088430067.1|2878235_2879195_-|AraC-family-transcriptional-regulator
MALTLSQRDYHELIQASATAATGATGDFEEKWHYPESLGQGYQHSIELRDGVQMDIARYQLRHQVMTTAEERPHPVECTFYLEGAYTDPPLGPKCYGLYGSGLAPGGTSIKPAEHPHAWLSLHIDPERLSQWLGSRALPLPELLRSPQQLYYSQFGTMTAPMQMVLHQILHCPYTGVIKQLYLESKAWELLTLCLHDALSQQQPPGPSINLKPADIERIHQARDILLRHFNNPPTLAELARQIHLNECALKRGFRQVFGTTVFGYLHHYRLDYARQLLQQGTKTVTGVAHTVGFASRSSFARAFRKKFGINPGQYLRQG
>NZ_CP021983.1|WP_080812085.1|2879451_2880186_-|hypothetical-protein
MSNPLATTDEVTFPDANLLITEDDTPVDNFASAKQQRLLVSSLYSSLRGSTFLAEANVGIYHAVNQPAVVPDVFISLDVQVPEAWWEKPNRCYLVWNFGKPPEVVLEVVSNRVGNELTSKLQTYAQMRVGYYVVYDPARQLGENPLYLYELRGLHYAELSEHWLEPMGIGLTLWQGEFEGRHDTWLRWCDAQGNMLLTGDEKAEQERQRAEQERQRAEQERQRAERLAAMLKARGIDPEELSDT
>NZ_CP021983.1|WP_080812087.1|2880498_2880834_-|HEPN-domain-containing-protein
MNDAQYEETQQWLIKSQRDLKVAQVLLDNEESLLDAVVYHCQQSAEKALKAYLASQNIAFVKTHDLDVLLGLCSSSKPDFQSLQEAADILTPYATEAVLVLKFVTQRLPEQ
>NZ_CP021983.1|WP_080812089.1|2880826_2881147_-|nucleotidyltransferase-domain-containing-protein
MPQLTLDLLEQMTQRLVAALKPEQIILFGSYAYGEPTKDSDIDLLVILSESDEPRYRRARKAHRALRGMGIPKDILVMTRAEVDRQASVSSSLVGQALRQGKVLYE
>NZ_CP021983.1|WP_080812091.1|2881179_2881455_-|DUF1636-domain-containing-protein
MNYGTLTRPKTKRSSSPMPLKGCVTGAVLLSKAVNRPTYLFTNLPDLPTVESAEALLQFVELYRQHDGESIPGRQFPEALQSAQVAKIPAV
>NZ_CP021983.1|WP_080812093.1|2881502_2882456_-|AraC-family-transcriptional-regulator
MTITLSQADYWELLQESVSDCFSEDTLNWVCAFSSALGQGVRRDLSLRDGIDLVIEDSCFQDDLVMQHCDRIHPVEYTFEQISLAGRRQQRYHFYGSGLAPGDPWRIPSCDRILRINVHIDPEVLQRWLGDTPQALNLLLRLPDEKFYEHSGAPTAAMQMTVQQILNCPFQGLTQRLYLESKVWELMVLLIETLQSGNDAPQSAYRLTPDDVERIHYASNLLHRRLLNPPSLIELARAIGINDHKLKVGFRQVFGTTVFGYLHQQRLERSRQLLESGDMNVTQAAHAVGFANRGHFAAAFRRKFGVNPGVYLRRRRG
>NZ_CP021983.1|WP_080812095.1|2882828_2883704_+|EfeM/EfeO-family-lipoprotein
MKTLLRNVLLSLLATLCIVGTASYTQQAVSSPSATAQAQLAQAADDPYAEQIDMGVAYFREKAAEQLALVKDFLAVLATGDLEAAKAAYIEARPPYEQIEVLAASFEQEDSDIDARPYSFEQGEASPDFISFHRIEALLFRDGDVAAAIPYAEGLVASVESLIDKLNDPSNFNSSLNFEGIIGLATEIPAKKISSEEETWSDQSLLIFKNNWIGIYSQVQPFETVLSAEIMTDVDAAYKACMDAIAPFYPDGQVAAMPYSSLSTADRKRISEASYQFRNALIEAAESLGLA
>NZ_CP021983.1|WP_088430069.1|2883891_2884536_-|tetratricopeptide-repeat-protein
MRAIRLSWWPFLLACLILPMQAGPAMAQSAQEVAQEGIEAYRAGDYEAAARAWRQLIELQPENPDAYNNLGATLYFLGDLEGSAAAYRRAIELDPDSATIYNNLGMVLVQQEQYQEAIAAYQQAIELDPEMAETYNNLGNLLEGEEAVAAYQQAVELNPDYAEAYNNLGTALANLERYEEAIAAYEQALAIDPDFTAAQENLTAVEQRLGATAE
>NZ_CP021983.1|WP_088430071.1|2885147_2886986_-|ABC-transporter-ATP-binding-protein
MGGSEQSYRQLLVTYLAPQRGRVMGLAVTLLGGIGLQVLNPQILRYFIDTAVAGGSQRLLVLAALGFMAIAFIRHGLAIASTYFSETVAWSATNDLRLDLAQHTLNLDLAFHKAHTPGELVERVDGDVDALSRFFSQFVLQVIGNGLLVVGILTILWVEDWRAGLSLSLFALVALGILGGLQSLAVAPWRHYRQVSAEFYGFVAEHLGGLEDIRANGAVDYVMQRLYRLLRRWLTVFHQARFTSTLLWGSTVGLFTLGHAIALAIGAYLWQRNAITIGTVYLLFYYATLLQDPIERIRQELEQFQQAIASVQRIQHLLSHRSSLLPGGQAVLPKGPLSVEFHEVWFRYEGEEKNFEFSGLSSQFNITQRDPTQHPELNTQNSLYTLQNLTLHLPAGQVLGLLGRTGSGKSTLARLLLRLYDIQRGQIRLAGINIAQVPLPELPLRVGFVTQDVQLFQTSVRNNLTFFNEHIPDQAILHTLDQLGLMPWLEQLPQGLDTELGADSGGLSAGQAQLLAFARVFLKDPGLVVLDEASSRLDPLTEQLIEQAVDRLLANRTGIIIAHRLKTVARADQILILEKGQIVEYGDRLSLAGDPNSRFAHLLRAGSATELA
>NZ_CP021983.1|WP_088430073.1|2887194_2887512_-|hypothetical-protein
MQCSWGQWSQELAQNHLMVEHPLIQTGGHPMGRAPNRSGIYRLTTRVVKYLMLALFAFLLVCLTAPIFSDFQVIGTLVSTISPWFWRLAIVTICLMATSAVAEAL

Crispr_ID: NZ_CP021983_21

• CRISPR_ID: NZ_CP021983_21
• CRISPR_location: 2964669-2964754
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP021983_21

Consensus_repeat	Method
CCCCATCACCCCATCACCCCATCTAC	CRISPRCasFinder

spacers of NZ_CP021983_21

>21.1|2964695|34|NZ_CP021983|CRISPRCasFinder
CCATCACCCCATCTACGTTCTCCGCTCTCCGTCC

CRISPR arrays and Neighbor proteins around NZ_CP021983_21

CRISPR arrays

The CRISPR arrays of NZ_CP021983_21

>merge|NZ_CP021983|21|2964669-2964754|CRISPRCasFinder
TCCGTCCTCCCCATCACCCCATCACCCCATCACCCCATCTACGTTCTCCGCTCTCCGTCCTCCGTCCTCCCCATCACCCCATCACC

>NZ_CP021983|21|22|2964669-2964754|CRISPRCasFinder
TCCGTCCTCCCCATCACCCCATCACC	CCATCACCCCATCTACGTTCTCCGCTCTCCGTCC
TCCGTCCTCCCCATCACCCCATCACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_080807670.1|2969707_2969941_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088430138.1|2965713_2966562_+|histone-deacetylase	unknown	unknown	gnl|CDD|212519
NZ_CP021983.1|WP_080807681.1|2966605_2967415_+|rhodanese-domain-containing-protein	unknown	unknown	gnl|CDD|223982
NZ_CP021983.1|WP_088430134.1|2955609_2957871_+|capsular-biosynthesis-protein	unknown	unknown	gnl|CDD|349772
NZ_CP021983.1|WP_080807679.1|2967432_2968089_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|366722
NZ_CP021983.1|WP_080807676.1|2968604_2968970_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080807737.1|2968420_2968612_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088430136.1|2959215_2960877_+|peptidase-M15A	unknown	unknown	gnl|CDD|311960
NZ_CP021983.1|WP_080807740.1|2953875_2955327_+|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|224512
NZ_CP021983.1|WP_080807710.1|2951642_2953403_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_CP021983.1|WP_080807686.1|2963048_2964047_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293840
NZ_CP021983.1|WP_080807700.1|2960883_2961450_-|DUF4231-domain-containing-protein	unknown	unknown	gnl|CDD|379418
NZ_CP021983.1|WP_080807693.1|2962046_2962847_-|KR-domain-containing-protein	unknown	unknown	gnl|CDD|223377
NZ_CP021983.1|WP_080807701.1|2958329_2959145_-|HAD-family-phosphatase	unknown	unknown	gnl|CDD|223635
NZ_CP021983.1|WP_080807664.1|2971106_2972279_-|histidine-kinase	unknown	unknown	gnl|CDD|236462
NZ_CP021983.1|WP_080807690.1|2962866_2963049_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080807697.1|2961597_2962032_+|hypothetical-protein	unknown	unknown	gnl|CDD|224442
NZ_CP021983.1|WP_080807673.1|2968963_2969536_-|cyclase	unknown	unknown	gnl|CDD|176875
NZ_CP021983.1|WP_080807667.1|2969973_2970993_-|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl|CDD|377085
NZ_CP021983.1|WP_080807684.1|2965414_2965639_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_088430138.1|2965713_2966562_+|histone-deacetylase	gnl|CDD|212519	cd09993, HDAC_classIV, Histone deacetylase class IV also known as histone deacetylase 11. Class IV histone deacetylases (HDAC11; EC 3.5.1.98) are predicted Zn-dependent enzymes. This class includes animal HDAC11, plant HDA2 and related bacterial deacetylases. Enzymes in this subfamily participate in regulation of a number of different processes through protein modification (deacetylation). They catalyze hydrolysis of N(6)-acetyl-lysine of histones (or other proteins) to yield a deacetylated proteins. Histone deacetylases often act as members of large multi-protein complexes such as mSin3A or SMRT/N-CoR. Human HDAC11 does not associate with them but can interact with HDAC6 in vivo. It has been suggested that HDAC11 and HDAC6 may use non-histone proteins as their substrates and play a role other than to directly modulate chromatin structure. In normal tissues, expression of HDAC11 is limited to kidney, heart, brain, skeletal muscle and testis, suggesting that its function might be tissue-specific. In mammals, HDAC11 proteins are known to be involved in progression of various tumors. HDAC11 plays an essential role in regulating OX40 ligand (OX40L) expression in Hodgkin lymphoma (HL); selective inhibition of HDAC11 expression significantly up-regulates OX40L and induces apoptosis in HL cell lines. Thus, inhibition of HDAC11 could be a therapeutic drug option for antitumor immune response in HL patients.	4.80577e-139
NZ_CP021983.1|WP_088430134.1|2955609_2957871_+|capsular-biosynthesis-protein	gnl|CDD|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	1.50342e-54
NZ_CP021983.1|WP_080807681.1|2966605_2967415_+|rhodanese-domain-containing-protein	gnl|CDD|223982	COG1054, COG1054, Predicted sulfurtransferase [General function prediction only].	6.23854e-142
NZ_CP021983.1|WP_080807679.1|2967432_2968089_-|methyltransferase-domain-containing-protein	gnl|CDD|366722	pfam01596, Methyltransf_3, O-methyltransferase. Members of this family are O-methyltransferases. The family includes catechol o-methyltransferase, caffeoyl-CoA O-methyltransferase and a family of bacterial O-methyltransferases that may be involved in antibiotic production.	1.14252e-81
NZ_CP021983.1|WP_088430136.1|2959215_2960877_+|peptidase-M15A	gnl|CDD|311960	pfam08291, Peptidase_M15_3, Peptidase M15.	8.37428e-21
NZ_CP021983.1|WP_080807740.1|2953875_2955327_+|sugar-ABC-transporter-substrate-binding-protein	gnl|CDD|224512	COG1596, Wza, Periplasmic protein involved in polysaccharide export, contains SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis].	5.88435e-32
NZ_CP021983.1|WP_080807710.1|2951642_2953403_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.88307e-46
NZ_CP021983.1|WP_080807686.1|2963048_2964047_+|MBL-fold-metallo-hydrolase	gnl|CDD|293840	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	8.23894e-56
NZ_CP021983.1|WP_080807700.1|2960883_2961450_-|DUF4231-domain-containing-protein	gnl|CDD|379418	pfam14015, DUF4231, Protein of unknown function (DUF4231). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea, eukaryotes and viruses. Proteins in this family are typically between 148 and 288 amino acids in length.	6.82867e-27
NZ_CP021983.1|WP_080807693.1|2962046_2962847_-|KR-domain-containing-protein	gnl|CDD|223377	COG0300, DltE, Short-chain dehydrogenases of various substrate specificities [General function prediction only].	6.99273e-57
NZ_CP021983.1|WP_080807701.1|2958329_2959145_-|HAD-family-phosphatase	gnl|CDD|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	4.84884e-24
NZ_CP021983.1|WP_080807664.1|2971106_2972279_-|histidine-kinase	gnl|CDD|236462	PRK09303, PRK09303, histidine kinase.	0
NZ_CP021983.1|WP_080807697.1|2961597_2962032_+|hypothetical-protein	gnl|CDD|224442	COG1525, COG1525, Micrococcal nuclease (thermonuclease) homologs [DNA replication, recombination, and repair].	4.86149e-27
NZ_CP021983.1|WP_080807673.1|2968963_2969536_-|cyclase	gnl|CDD|176875	cd08866, SRPBCC_11, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	2.77393e-25
NZ_CP021983.1|WP_080807667.1|2969973_2970993_-|YihY/virulence-factor-BrkB-family-protein	gnl|CDD|377085	pfam03631, Virul_fac_BrkB, Virulence factor BrkB. This family acts as a virulence factor. In Bordetella pertussis, BrkB is essential for resistance to complement-dependent killing by serum. This family was originally predicted to be ribonuclease BN, but this prediction has since been shown to be incorrect.	8.9452e-53

Protein sequences

>NZ_CP021983.1|WP_080807686.1|2963048_2964047_+|MBL-fold-metallo-hydrolase
MNQLRRWAIGWLVALITLAAIVGLQTQTPAQAPSELTLNRAGLTLEELADGVYGLIASTDFPPSDPAMAICNGGIVIGSDGVLVIDPFQTEELANLLFATVANLTDQPIRYVVNTHYHFDHSGGNAAAKALDLPILGRGPIREFMLSRNLEMDPNATPPEVIVNGAGELWLGERQIQLTEFDGHSGGTDLVIYIPDADVLMAGDLLFSQRLPYLGDGNIRVWQQTLEHLAVDYDTATILPGHGPVSDRTHLTTLKDYLEQLETWAMTWEAAGLSQAEAIEQTPLPDTYSDYLFQALFPGNLEVAYQQITLGHDDAAAIERYFQAQAPALQAL
>NZ_CP021983.1|WP_080807690.1|2962866_2963049_+|hypothetical-protein
MDSLGSSGYSHEPSTAVGNEWGHLSIDAVYRIGAPLPLSEADAHSKTEDYRCRQIRPPQS
>NZ_CP021983.1|WP_080807693.1|2962046_2962847_-|KR-domain-containing-protein
MTQLQQAFILITGASGGFGQEFCRQLLALDGQLILTDIHGPTLEQQAAILSHSVSPGKILACLTADLASRDGCDSLYQQIQGLGYPVDVLINNAGRGCVGRLDEVPAEQWEQLMQVNLLAPMRLSALFANVMVQRRRGHIVNLSSLAGWIAPPGLVPYAASKFGLRGFSQGLARELAPYRVQVTAVYPGFSRTPILQSPRYGSLAGSMAALPDWLVSEPASVIRATIRAIQRNQRQVFPDRVGPIVQRLQRFTPGLVPWLSHILDA
>NZ_CP021983.1|WP_080807697.1|2961597_2962032_+|hypothetical-protein
MALPRHSFHLNVIKDGDTLIASGNNITESVRLYGIDCPELAQAPYGEAARQRIQKLLEPYDTIEVIEVDRDRHGRLVGEVWVEDGCINTQLLAEGHAVAYGRHLKGEFRDRYVQAEAIARKARLNFWQQPRPEMPWDYRQRHPH
>NZ_CP021983.1|WP_080807700.1|2960883_2961450_-|DUF4231-domain-containing-protein
MAKQTYADFLKQDFKQLFDALNLDDIQRHYLRSRWLDQVIWMEKKAAFCRDWYYRLRLTAITLGIIVPILLGLEFTNPRASQVKKYLAIGLSGVVAVSAAIEEFFHYGERWYHYRRTVESLKTHGWQFSQLSGQYSDYDTCKAAFDDFTDQIEELIQRDVEIYVTQIAQQDKTQKSQQKQSKLPREQT
>NZ_CP021983.1|WP_088430136.1|2959215_2960877_+|peptidase-M15A
MATLLPDQRNDYYLSEAARVGIHKPILAALYAVHGQPQLPDGELGLGIYPVNRVGPDQVNTFPEQVQYAANTVRSLTDSLTAEGWQGRDLWNASESRYSDRLLRTLAAGYRPPASDTSAALLEASDFNTLKDAYLADIVYDYEADQLPHNPAHLDKALLAFAERVPPHYGRLGFQRQALLEAVRLWRKLDSHEAVLEALEISEPVSQADETALDQALVNFVQGAVRYYSGYPYQREALLRLVQLWRQMDSREETIQWLASHDPHAHEANLHIIDPALIAFVQHLPGQYKGQGDQRFALTEAYRLWQQLASRAMALESLGVDPRTVVQQADDKTALTETAAQIDQGLLAFIKSVPQTYQETETQREALIRLVQIWRRLEGRIPTLQALCDDLRRMERAQRHAVEAMPAPEAAPQPPRPPRWTPENVQLAASIVPNGNFTWAEATHGGTRLPPNQATIDAMVRIAALAQQARDRIGRPFKVTSWYRPPEINARVGGASQSRHIIGDAIDFYCDGLSGNQLYWALDPWWPGGLGRYRRFPYLAHLDARGYRARWTH
>NZ_CP021983.1|WP_080807701.1|2958329_2959145_-|HAD-family-phosphatase
MARLQSLTTSEFIQTRRHIRLIATDMDGTLTQAGQLTPGLLQALIELQAAGLAVLIVTGRSVGWVQGLVSYLPVAGAIAENGGLYMAKPDLQLQPLVDLRDITAHRQQLAQLFAQLQGQYPQLRESSDNRFRLSDWTFDVAGLSPDTLTSLQATCAHQGWGFTYSTVQCHLKLPHQDKAPGLQTVLRRYFPDLSPEQVLTVGDSPNDQSLFDTAYFPYSVGVANVAHYCDGRRLAPGGHPMTHLPTYLTTAAEAAGFCELVQQLLAQAHHP
>NZ_CP021983.1|WP_088430134.1|2955609_2957871_+|capsular-biosynthesis-protein
MNADSSLPVTAEKSFLPNRSDDEGGIDLGQIIDAIRRRLLLVAGVTTVVASAAVLKALTDTPIYEASFEILTNPVTLETRIISAANPQTLSNQQDVVAVSVDEAKLKILKSPKVIDPVVEELQETFPAIDYGDVARGLTVQPTSQDILTVTYQHPDPAVVTAVLDVVEDAFLQFSLEERQRDILRGIDFVDEQLPQLRSRVDALQSQLEALRRQYNLIDPEAQGQQLTQQISSFSQERLDIRVQLNEAKLLYDNLDQQLDQQGELAAASLLNENPRYQSLLDKLLEIDTQLAEDSVLFMGESPEIQYLREQRQQLLPLLAQEGQRTERQLVSMIRELETRDQALGQAIDQLNQRMKVLSSVARRYSDIQRELQIATENLNQFLSKREALRIDAAQRQTPWELLSQPGNPRASAASVKRNLLLGSVLGVLLGIGAALLIDRLSSVIYTPKELKSLSKLPLLGVIPFNEYLERYGPAASVATRLRQAGYILNITNKADEQEQSQASTPFIESFRSLYASLRLLNPDRSLTSLTVSSATPGAGKTTVCLHLGQAAAAMGRRVLLVDTDLRRPSLHKKIGMKNAKGLTDYIASPELSIEEVTQPVPLDDNLSIITAGSLPPDPTKVLSSRRMEEFIGMVNQQFDLVIYDTPPLLGFADAFLTGVHSNGFLMVVGLGKVKRTVFQQALEDLKVSMIPVLGLVANGAKEDQMASSYSYYQYYTQDEALPSQTNGALKTEPAGLLKSLKDLPIVKSMTKK
>NZ_CP021983.1|WP_080807740.1|2953875_2955327_+|sugar-ABC-transporter-substrate-binding-protein
MTSYRLFPPQLMSPLAGLTLLTFVAVSLPATASLPSQRATPPPPPPSTLESAYRLGAGDRIRIDIFRVPQYSGEHDLLVDGSINLPVAGSVDLAGLTLDQASEAIAIAYSNILRRPRITVSLVTPRPLRIGIAGEVTEPGSYTLNSGETPTITALLEAAGGLTQMADLRQVQIYRSQRFGPNQIINVNLWQLLQTGDLRYDVTLRDGDTVRVPTAASLNLAEALQMSTASFASNESRPLNVAVVGEVFRPGPYTVTGTARTGAAGVPGGGGGTAIPPTVTRAIQVAGGIRPMANIRDIQIRRQTRTAGEQTIAVNLWQLLQTGDLTQDIVLQEGDTVIVPTATAIDEEEAAQIAAASFSPDTVKVNVVGEVGRPGIIEVAPNTPLNQALLAAGGFNNRASRGEVDLVRLNPDGTVEQREIPVDFTQGLDDETNPPIRNNDVIIVGRSTPATIGDTLDTIARPISSAISLFTIPLTLLRLFESF
>NZ_CP021983.1|WP_080807710.1|2951642_2953403_-|serine/threonine-protein-kinase
MTDFPDFTPYGYTLTDVLGCNRAGGRVTYLAQDCNHCTEVVIKQFQFAQTTAWSDLEAHEREIEVLRSLNHPGIPRYLDSFQTDNGFCMVQEYKQARPLSATRSFGPAEVRQLAIALLEILVYLQSRFPPVIHRDIKPDNILVDDHLRVYLVDFGFARIGDGEVGVSSVVKGTLGFMPPEQLFNRALTEASDLYGLGMTLVCLLTKTQPDAIGDLVDISYRVKFKHLLPTVNRPWINWLERLVEPRLKDRYSNAVTALEAVPNCAIYSPKVHLSTATIQLAATQSRQTLTHSLHIHNPIPETTLQGTWTIEPHPSDGPSDLQRHPWISVQPASFAGNRIDCQITVDVGRLMPDRLYERTLRLTSNALPEAYTLPLQVRTASVLAQKSQTYWQSLSLLFLFALFLYRGVYWFVGNPLAVDGNLALASFGTAAGTAAGFEIAGWTLATTGATISANASIIAGGGVGLITFLVAWSMAGAIGGSLTEILLGGGVGLASGWIAGIALGMTVEALINRYLSPGFAIRLALLTMALGCSLSLGLTIGLMRPEILALLTLLSLSLGTHLIQEPLRRARIIAHQQRTHRHLIRP
>NZ_CP021983.1|WP_080807684.1|2965414_2965639_+|hypothetical-protein
MSSEATPPQAGTKPSSPAGQQGASPATTAATSSPGSTSAAVTVVPADHPHPLDVPDSLVHDLDLRQRRPLSSLL
>NZ_CP021983.1|WP_088430138.1|2965713_2966562_+|histone-deacetylase
MAKFGGLYHHLLQERVIEPTQVYQPGAPPLEWLTLVHGVGYVTAYCQGHLEAKAQRRIGLPWSPDLVQRTCAVVGGTILTAKLALRHGLACNTAGGTHHAFPDYGTGFCIFNDLAVAARVLLQQALVQQVLIIDLDVHQGDGTAWIFNQDPRVFTFSMHCAVNFPGTKQLSDLDVPLPAGMQDDAYLKTLMDYLPSLLQQVNPDLVLYDAGVDTHQADRLGKLAMSDAGIYRRDHCVLKTCARAGYPVACVIGGGYGDDMEALIWRHSLVHRAATAVFRELI
>NZ_CP021983.1|WP_080807681.1|2966605_2967415_+|rhodanese-domain-containing-protein
MAFIVATFYKFVPLSNTQELRSHLLSWGQALNLRGTICLAPEGINGTLAGDQPAIDQMLHQLRQHPVLADITPRTATTPTLPFERFKVKLKPEIVTLGRPEVNPIQQVGTYVSPQDWNALISDPEVLVLDTRNHYEVSIGSFQGAINPATDRFREFPAYVAQLNPTVHKRVAMFCTGGIRCEKASAYLLQQGFEQVYHLQGGILNYLETIPETESLWQGECFVFDDRVAVGHGLQPGIHQMCQGCGHPVSPEDQASPQYLPGHWCPHCL
>NZ_CP021983.1|WP_080807679.1|2967432_2968089_-|methyltransferase-domain-containing-protein
MTRKTLNLDESLYTYLLDHSLREPESLARLRQETANQPMAQMQISPEQGQFMALLVRLMGAKWTLEVGVFTGYSALAVALALPPEGKLVACDISEDYTAIARRHWQQAGVADKIDLRLAPALETLDQLLVEGTRFDFAFIDADKRNYLAYYERTLQLLRPGGLMTIDNVLWSGRVADDTVKDAQTEAIRAFNQALYEDDRVDLSLVPIADGLTLALKR
>NZ_CP021983.1|WP_080807737.1|2968420_2968612_+|hypothetical-protein
MSESSVVQISAVTGWIIGISHVKDSGYQCWVINPDLDVLSDGTLYSTSSAAMSAGRAFVERFS
>NZ_CP021983.1|WP_080807676.1|2968604_2968970_-|hypothetical-protein
MLKRLKGSLVMGVGYMLSPLSWWNDLFFNLPIAYGFAYVVTWGQPDWFWAATVVGYWLSNVLGIVMMQWGAVDLFFSQRQANWRRDLLISLGSSTAYTLVVAALLYTHLLPVPEFLAQAPN
>NZ_CP021983.1|WP_080807673.1|2968963_2969536_-|cyclase
MVLALERPPHLLVDVPHPSDHCLQALLRGQIVVDTYGYTEAGKAVTAQMYVPLMRSHLWEQLTHYSRWTQYFPNIVHSELLASHHRGSQGCRRLYQVGRKAFLMMNAQVEIYLNVFETLHRRIQFRFERGSFTDFAADLTLQDCQGGTLLTYSVQATPLIPVPGFLVEQAMRHDLPGNMEQMRRVLCRSC
>NZ_CP021983.1|WP_080807670.1|2969707_2969941_+|hypothetical-protein
MLLTTVGCHLFRVPFVISPMSSRRPETQLFIVLAVLTLAVWVLRGLTILAFLPGIILWLLLLTSIATGIVSSWRSMH
>NZ_CP021983.1|WP_080807667.1|2969973_2970993_-|YihY/virulence-factor-BrkB-family-protein
MPMRRIRRALSVRAFIRFLRCLLTPKTLREVVRRTGEQRLPSLASEMAYNAILGLFPGILALLTAIGLVASLEATLMQLASRLSDVTPVEALTVIRNFTQEVNQGNSSRLFSLSFGFSLWAASGAVSAAMRALDEIHEVPRGQSRPFWKAKLVSLGLTLGTLLLLLVACALVFVSNWLVHRVAAQGGPMISLGLLHLWRWLSWPLALAIVAAAFVLIYRFGPSRWQPGKPLVPGAVLAALAWAGLSMGFRLYGAHFGHFNRVYGAVGAVIVLLLWLYLGSLSMLMGDQLNVTVGDDLRQRAVRRGLRPQGPGLPVAPPSFESFTIRRREDGASPKRWSP
>NZ_CP021983.1|WP_080807664.1|2971106_2972279_-|histidine-kinase
MEATSQASQASKVPLKLLLFIDKRPSSSDHVRQIRQYLKSLEEHFHINLDVVDVGEHPYLAEHYRLVASPALIKIAPLPQRTLTGSDIVPQLQHWWPRWHQNAQAQVAPAADGASGDELVFYDPNDSIAHSAELMKLSDDIFRLNQVKEELEAQLRFKNRIIAMMAHDLRNPLTAASIAVETLEMGYGHQQEGTTKLSPELTNQLLKHVKTQIRAIDRMITDILQTARGASAELQIQPQDMDLKALCFDVLGAMKNRIREKQQRVQIDIPQDLPHVYADGSQIRRVILNLLDNAIKYTPLKGTVEVMALHRTNQKVQVTIHDSGPGIPEENRDNIFEERFRLQRDESQDGYGLGLALCQRILRAHYGQIWVDSVVNEGSYFHFTLPVYRA

Crispr_ID: NZ_CP021983_22

• CRISPR_ID: NZ_CP021983_22
• CRISPR_location: 3044329-3045219
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 12 spacers

Consensus repeat of NZ_CP021983_22

Consensus_repeat	Method
CTTCCCACTAGGT-GGGAAACTAATTGAATGGAAAC	PILER-CR
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	CRISPRCasFinder
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	CRT

spacers of NZ_CP021983_22

>22.1|3044364|35|NZ_CP021983|PILER-CR,CRISPRCasFinder,CRT
ATGCAAGCATACGTACACCTCACCCTCGACTCATC
>22.2|3044434|38|NZ_CP021983|PILER-CR,CRISPRCasFinder,CRT
ATCCAGTCCGCTCGCTTCTTGTATAGAAGCTTGTAGAC
>22.3|3044507|35|NZ_CP021983|PILER-CR,CRISPRCasFinder,CRT
AAGTCTTGGACGAGGGCGGATTAGCTTTTTCTCAA
>22.4|3044577|41|NZ_CP021983|PILER-CR,CRISPRCasFinder,CRT
CGCTTCCACAATTCAGCTGGGCACCTGCCCAGCTTCTCGGG
>22.5|3044653|34|NZ_CP021983|PILER-CR,CRISPRCasFinder,CRT
GGGCCTCCCACTCTTTCCGGGTCGCCCAGATGAT
>22.6|3044722|39|NZ_CP021983|PILER-CR,CRISPRCasFinder,CRT
TTCCGTTTCCTCCTGATGGGAGGAAGGCCTTGACTGGAT
>22.7|3044796|36|NZ_CP021983|PILER-CR,CRISPRCasFinder,CRT
CCATCAGAAGCTCTATATCGCGCCTTGATGGAACCG
>22.8|3044867|36|NZ_CP021983|PILER-CR,CRISPRCasFinder,CRT
TCCTGAGCCTGTTCACGACTCATCTTCGAGACTCGA
>22.9|3044938|35|NZ_CP021983|PILER-CR,CRISPRCasFinder,CRT
TCTGTTTGGCCGGTGATGGTGTCAGATAACGCGTG
>22.10|3045008|36|NZ_CP021983|PILER-CR,CRISPRCasFinder,CRT
ATTCGCGCACCACCCGGGGGTGATGATGACTTCAGA
>22.11|3045079|36|NZ_CP021983|PILER-CR,CRISPRCasFinder,CRT
ATTCGCGCACCACCCGGGGGTGATGATGACTTCAGA
>22.12|3045150|35|NZ_CP021983|PILER-CR,CRISPRCasFinder,CRT
TCCTAAAGAGTCCTCCAGGAATTGCAGCAAGGCGA

CRISPR arrays and Neighbor proteins around NZ_CP021983_22

CRISPR arrays

The CRISPR arrays of NZ_CP021983_22

>merge|NZ_CP021983|22|3044329-3045219|PILER-CR,CRISPRCasFinder,CRT
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAACATGCAAGCATACGTACACCTCACCCTCGACTCATCCTTCCCACTAGGTGGGAAACTAATTGAATGGAAACATCCAGTCCGCTCGCTTCTTGTATAGAAGCTTGTAGACCTTCCCACTAGGTGGGAAACTAATTGAATGGAAACAAGTCTTGGACGAGGGCGGATTAGCTTTTTCTCAACTTCCCACTAGGTGGGAAACTAATTGAATGGAAACCGCTTCCACAATTCAGCTGGGCACCTGCCCAGCTTCTCGGGCTTCCCACTAGGTGGGAAACTAATTGAATGGAAACGGGCCTCCCACTCTTTCCGGGTCGCCCAGATGATCTTCCCACTAGGTGGGAAACTAATTGAATGGAAACTTCCGTTTCCTCCTGATGGGAGGAAGGCCTTGACTGGATCTTCCCACTAGGTGGGAAACTAATTGAATGGAAACCCATCAGAAGCTCTATATCGCGCCTTGATGGAACCGCTTCCCACTAGGTGGGAAACTAATTGAATGGAAACTCCTGAGCCTGTTCACGACTCATCTTCGAGACTCGACTTCCCACTAGGTGGGAAACTAATTGAATGGAAACTCTGTTTGGCCGGTGATGGTGTCAGATAACGCGTGCTTCCCACTAGGTGGGAAACTAATTGAATGGAAACATTCGCGCACCACCCGGGGGTGATGATGACTTCAGACTTCCCACTAGGTGGGAAACTAATTGAATGGAAACATTCGCGCACCACCCGGGGGTGATGATGACTTCAGACTTCCCACTAGGTGGGAAACTAATTGAATGGAAACTCCTAAAGAGTCCTCCAGGAATTGCAGCAAGGCGACTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC

>NZ_CP021983|22|11|3044329-3045219|PILER-CR
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	ATGCAAGCATACGTACACCTCACCCTCGACTCATC
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	ATCCAGTCCGCTCGCTTCTTGTATAGAAGCTTGTAGAC
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	AAGTCTTGGACGAGGGCGGATTAGCTTTTTCTCAA
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	CGCTTCCACAATTCAGCTGGGCACCTGCCCAGCTTCTCGGG
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	GGGCCTCCCACTCTTTCCGGGTCGCCCAGATGAT
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	TTCCGTTTCCTCCTGATGGGAGGAAGGCCTTGACTGGAT
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	CCATCAGAAGCTCTATATCGCGCCTTGATGGAACCG
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	TCCTGAGCCTGTTCACGACTCATCTTCGAGACTCGA
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	TCTGTTTGGCCGGTGATGGTGTCAGATAACGCGTG
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	ATTCGCGCACCACCCGGGGGTGATGATGACTTCAGA
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	ATTCGCGCACCACCCGGGGGTGATGATGACTTCAGA
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	TCCTAAAGAGTCCTCCAGGAATTGCAGCAAGGCGA
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC

>NZ_CP021983|22|23|3044329-3045219|CRISPRCasFinder
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	ATGCAAGCATACGTACACCTCACCCTCGACTCATC
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	ATCCAGTCCGCTCGCTTCTTGTATAGAAGCTTGTAGAC
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	AAGTCTTGGACGAGGGCGGATTAGCTTTTTCTCAA
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	CGCTTCCACAATTCAGCTGGGCACCTGCCCAGCTTCTCGGG
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	GGGCCTCCCACTCTTTCCGGGTCGCCCAGATGAT
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	TTCCGTTTCCTCCTGATGGGAGGAAGGCCTTGACTGGAT
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	CCATCAGAAGCTCTATATCGCGCCTTGATGGAACCG
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	TCCTGAGCCTGTTCACGACTCATCTTCGAGACTCGA
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	TCTGTTTGGCCGGTGATGGTGTCAGATAACGCGTG
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	ATTCGCGCACCACCCGGGGGTGATGATGACTTCAGA
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	ATTCGCGCACCACCCGGGGGTGATGATGACTTCAGA
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	TCCTAAAGAGTCCTCCAGGAATTGCAGCAAGGCGA
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC

>NZ_CP021983|22|10|3044329-3045219|CRT
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	ATGCAAGCATACGTACACCTCACCCTCGACTCATC
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	ATCCAGTCCGCTCGCTTCTTGTATAGAAGCTTGTAGAC
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	AAGTCTTGGACGAGGGCGGATTAGCTTTTTCTCAA
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	CGCTTCCACAATTCAGCTGGGCACCTGCCCAGCTTCTCGGG
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	GGGCCTCCCACTCTTTCCGGGTCGCCCAGATGAT
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	TTCCGTTTCCTCCTGATGGGAGGAAGGCCTTGACTGGAT
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	CCATCAGAAGCTCTATATCGCGCCTTGATGGAACCG
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	TCCTGAGCCTGTTCACGACTCATCTTCGAGACTCGA
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	TCTGTTTGGCCGGTGATGGTGTCAGATAACGCGTG
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	ATTCGCGCACCACCCGGGGGTGATGATGACTTCAGA
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	ATTCGCGCACCACCCGGGGGTGATGATGACTTCAGA
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC	TCCTAAAGAGTCCTCCAGGAATTGCAGCAAGGCGA
CTTCCCACTAGGTGGGAAACTAATTGAATGGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_080808023.1|3041788_3042145_+|DUF1579-domain-containing-protein	unknown	unknown	gnl|CDD|377882
NZ_CP021983.1|WP_088431687.1|3052753_3053521_+|protein-tyrosine-phosphatase	unknown	unknown	gnl|CDD|350348
NZ_CP021983.1|WP_080808033.1|3040666_3041098_+|glyoxalase	unknown	unknown	gnl|CDD|319943
NZ_CP021983.1|WP_080808008.1|3049769_3050351_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NZ_CP021983.1|WP_080808030.1|3041132_3041549_+|VOC-family-protein	unknown	unknown	gnl|CDD|319899
NZ_CP021983.1|WP_080808035.1|3039999_3040410_+|ketosteroid-isomerase	unknown	unknown	gnl|CDD|226769
NZ_CP021983.1|WP_080808000.1|3051123_3051372_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080807998.1|3051681_3052509_-|response-regulator	unknown	unknown	gnl|CDD|381085
NZ_CP021983.1|WP_088430164.1|3050360_3050756_-|hypothetical-protein	unknown	unknown	gnl|CDD|274519
NZ_CP021983.1|WP_080808014.1|3046464_3047424_-|EamA/RhaT-family-transporter	unknown	unknown	gnl|CDD|273359
NZ_CP021983.1|WP_088430166.1|3050836_3051079_-|hypothetical-protein	unknown	unknown	gnl|CDD|274519
NZ_CP021983.1|WP_080808037.1|3039564_3039981_+|aldehyde-activating-protein	unknown	unknown	gnl|CDD|226314
NZ_CP021983.1|WP_088431685.1|3042754_3043393_+|glutathione-S-transferase-family-protein	unknown	unknown	gnl|CDD|223698
NZ_CP021983.1|WP_080808043.1|3038378_3038624_+|hypothetical-protein	unknown	unknown	gnl|CDD|226769
NZ_CP021983.1|WP_080808026.1|3041562_3041787_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080808040.1|3038677_3039538_+|class-D-beta-lactamase	unknown	unknown	gnl|CDD|225322
NZ_CP021983.1|WP_080808049.1|3037222_3037645_+|YciI-family-protein	unknown	unknown	gnl|CDD|226318
NZ_CP021983.1|WP_080808011.1|3047472_3049308_-|hypothetical-protein	unknown	unknown	gnl|CDD|276809
NZ_CP021983.1|WP_080808017.1|3046033_3046468_+|peptidylprolyl-isomerase	unknown	unknown	gnl|CDD|223976
NZ_CP021983.1|WP_088430162.1|3045309_3045891_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_080808023.1|3041788_3042145_+|DUF1579-domain-containing-protein	gnl|CDD|377882	pfam07617, DUF1579, Protein of unknown function (DUF1579). A family of paralogous hypothetical proteins identified in Rhodopirellula baltica that also has members in Gloeobacter violaceus, Sinorhizobium meliloti and Agrobacterium tumefaciens.	2.57461e-41
NZ_CP021983.1|WP_088431687.1|3052753_3053521_+|protein-tyrosine-phosphatase	gnl|CDD|350348	cd14498, DSP, dual-specificity phosphatase domain. The dual-specificity phosphatase domain is found in typical and atypical dual-specificity phosphatases (DUSPs), which function as protein-serine/threonine phosphatases (EC 3.1.3.16) and protein-tyrosine-phosphatases (EC 3.1.3.48). Typical DUSPs, also called mitogen-activated protein kinase (MAPK) phosphatases (MKPs), deactivate MAPKs by dephosphorylating the threonine and tyrosine residues in the conserved Thr-Xaa-Tyr motif residing in their activation sites. All MKPs contain an N-terminal Cdc25/rhodanese-like domain, which is responsible for MAPK-binding, and a C-terminal catalytic dual specificity phosphatase domain. Atypical DUSPs contain the catalytic dual specificity phosphatase domain but lack the N-terminal Cdc25/rhodanese-like domain that is present in typical DUSPs or MKPs. Also included in this family are dual specificity phosphatase-like domains of catalytically inactive members such as serine/threonine/tyrosine-interacting protein (STYX) and serine/threonine/tyrosine interacting like 1 (STYXL1), as well as active phosphatases with substrates that are not phosphoproteins such as PTP localized to the mitochondrion 1 (PTPMT1), which is a lipid phosphatase, and laforin, which is a glycogen phosphatase.	4.60546e-33
NZ_CP021983.1|WP_080808033.1|3040666_3041098_+|glyoxalase	gnl|CDD|319943	cd08355, TioX_like, Micromonospora sp. TioX and similar proteins. Micromonospora sp. TioX is encoded by a gene of the thiocoraline biosynthetic gene cluster. Thiocoraline is a thiodepsipeptide with potent antitumor activity. TioX may be involved in thiocoraline resistance or secretion. TioX belongs to vicinal oxygen chelate (VOC) superfamily that is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	5.46435e-51
NZ_CP021983.1|WP_080808008.1|3049769_3050351_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.17261e-23
NZ_CP021983.1|WP_080808030.1|3041132_3041549_+|VOC-family-protein	gnl|CDD|319899	cd06588, PhnB_like, Escherichia coli PhnB and similar proteins. The Escherichia coli phnB gene is found next to an operon of fourteen genes (phnC-to-phnP) related to the cleavage of carbon-phosphorus (C-P) bonds in unactivated alkylphosphonates, supporting bacterial growth on alkylphosphonates as the sole phosphorus source. It was originally considered part of that operon. PhnB appears to play no direct catalytic role in the usage of alkylphosphonate. Although many of the proteins in this family have been annotated as 3-demethylubiquinone-9 3-methyltransferase enzymes by automatic annotation programs, the experimental evidence for this assignment is lacking. In Escherichia coli, the gene coding 3-demethylubiquinone-9 3-methyltransferase enzyme is ubiG, which belongs to the AdoMet-MTase protein family. PhnB-like proteins adopt a structural fold similar to bleomycin resistance proteins, glyoxalase I, and type I extradiol dioxygenases.	8.33295e-42
NZ_CP021983.1|WP_080808035.1|3039999_3040410_+|ketosteroid-isomerase	gnl|CDD|226769	COG4319, COG4319, Ketosteroid isomerase homolog [Function unknown].	9.86636e-22
NZ_CP021983.1|WP_088430164.1|3050360_3050756_-|hypothetical-protein	gnl|CDD|274519	TIGR03323, alt_F1F0_F1_gam, alternate F1F0 ATPase, F1 subunit gamma. A small number of taxonomically diverse prokaryotic species, including Methanosarcina barkeri, have what appears to be a second ATP synthase, in addition to the normal F1F0 ATPase in bacteria and A1A0 ATPase in archaea. These enzymes use ion gradients to synthesize ATP, and in principle may run in either direction. This model represents the F1 gamma subunit of this apparent second ATP synthase.	7.1204e-45
NZ_CP021983.1|WP_080808014.1|3046464_3047424_-|EamA/RhaT-family-transporter	gnl|CDD|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	2.90579e-11
NZ_CP021983.1|WP_088430166.1|3050836_3051079_-|hypothetical-protein	gnl|CDD|274519	TIGR03323, alt_F1F0_F1_gam, alternate F1F0 ATPase, F1 subunit gamma. A small number of taxonomically diverse prokaryotic species, including Methanosarcina barkeri, have what appears to be a second ATP synthase, in addition to the normal F1F0 ATPase in bacteria and A1A0 ATPase in archaea. These enzymes use ion gradients to synthesize ATP, and in principle may run in either direction. This model represents the F1 gamma subunit of this apparent second ATP synthase.	0.00287794
NZ_CP021983.1|WP_080808037.1|3039564_3039981_+|aldehyde-activating-protein	gnl|CDD|226314	COG3791, COG3791, Uncharacterized conserved protein [Function unknown].	3.01339e-14
NZ_CP021983.1|WP_088431685.1|3042754_3043393_+|glutathione-S-transferase-family-protein	gnl|CDD|223698	COG0625, Gst, Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	1.91876e-26
NZ_CP021983.1|WP_080808043.1|3038378_3038624_+|hypothetical-protein	gnl|CDD|226769	COG4319, COG4319, Ketosteroid isomerase homolog [Function unknown].	6.3193e-12
NZ_CP021983.1|WP_080808011.1|3047472_3049308_-|hypothetical-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	0.00122445
NZ_CP021983.1|WP_080808040.1|3038677_3039538_+|class-D-beta-lactamase	gnl|CDD|225322	COG2602, COG2602, Beta-lactamase class D [Defense mechanisms].	7.97366e-80
NZ_CP021983.1|WP_080808049.1|3037222_3037645_+|YciI-family-protein	gnl|CDD|226318	COG3795, COG3795, Uncharacterized protein conserved in bacteria [Function unknown].	6.82385e-46
NZ_CP021983.1|WP_080807998.1|3051681_3052509_-|response-regulator	gnl|CDD|381085	cd00156, REC, phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response regulators (PRRs). Two-component systems (TCSs) involving a sensor and a response regulator are used by bacteria to adapt to changing environments. Processes regulated by two-component systems in bacteria include sporulation, pathogenicity, virulence, chemotaxis, and membrane transport. Response regulators (RRs) share the common phosphoacceptor REC domain and different effector/output domains such as DNA, RNA, ligand-binding, protein-binding, or enzymatic domains. Response regulators regulate transcription, post-transcription or post-translation, or have functions such as methylesterases, adenylate or diguanylate cyclase, c-di-GMP-specific phosphodiesterases, histidine kinases, serine/threonine protein kinases, and protein phosphatases, depending on their output domains. The function of some output domains are still unknown. TCSs are found in all three domains of life - bacteria, archaea, and eukaryotes, however, the presence and abundance of particular RRs vary between the lineages. Archaea encode very few RRs with DNA-binding output domains; most are stand-alone REC domains. Among eukaryotes, TCSs are found primarily in protozoa, fungi, algae, and green plants. REC domains function as phosphorylation-mediated switches within RRs, but some also transfer phosphoryl groups in multistep phosphorelays.	1.30642e-23
NZ_CP021983.1|WP_080808017.1|3046033_3046468_+|peptidylprolyl-isomerase	gnl|CDD|223976	COG1047, SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones].	6.37176e-43

Protein sequences

>NZ_CP021983.1|WP_088431685.1|3042754_3043393_+|glutathione-S-transferase-family-protein
MTDLILTTFDWVPKTPRGYVRDIRVRWALEEARLPYSVTSVPFRDRSAEHFSHQPFGQVPWLTDGDISIFESGAILLHLGELSDRLMPAEPHGRSEVIQWLFAALNSVEMASLPWSLFKFSGDTEGTPGRKHLDEFLKARLHHMEKVLAGRQWLTATFSVADILMADVLRLVDRFDGLVESPACRDYVAHATARPAFVKAHADQMAHFAKAD
>NZ_CP021983.1|WP_080808023.1|3041788_3042145_+|DUF1579-domain-containing-protein
MSPFRLRRNTILGQGEMCGEGGDMTSIMTLGYNPQTQRYVGTWVGSMMSLLWVYDGELDAARQVLTLISEGPAMTGDGTAQYRDEIAFEDDDHRVMTSHMMRADGQWHWFMTAHYRRR
>NZ_CP021983.1|WP_080808026.1|3041562_3041787_+|hypothetical-protein
MTLTLEELQEKLADINQLVANLQTSAAFEKYYADDIVMIEGDGTVTTGKNACRRGREFFFKEMLIEFRESKLIS
>NZ_CP021983.1|WP_080808030.1|3041132_3041549_+|VOC-family-protein
MKLIPYLNFDGDCEAAFTFYEQVFGGKLGDKMIYKGSPMEADVPPEWHDKIMHTHLTIGDQEIMGSDAPPAYFKEPQGTEVTIQIDDPEKAEQIFRALAENGTVKMDIQETFWAKRFGMLTDQFGIPWMVNCDKAPEE
>NZ_CP021983.1|WP_080808033.1|3040666_3041098_+|glyoxalase
MTNDAKTAIATIIPTLRYRDASAAVDWLCQAFGFEKHLVVPDDDGGIAHAELVFGNGMVMVGAACEDEFGRLQQPPSQGNAVVTQSPYILVEDVDKHYERAVAAGAQIVTDIKDQDYGGRDYSCRDPEGHVWNFGTYDPWTAG
>NZ_CP021983.1|WP_080808035.1|3039999_3040410_+|ketosteroid-isomerase
MADNDTQSTRKASIQNLLEQWASATRFGKQDDVLVNHAPDVTIFDVLPPLQYESADAYRQSWDEWQPTTKGPGIFELHNLKITAGKDVAFAYGLIRCGGTKPDGKTFEDWVRATFCLCNVNGNWRITHQHISMPIG
>NZ_CP021983.1|WP_080808037.1|3039564_3039981_+|aldehyde-activating-protein
MKTTEISCLCGTVKVQLTGHPITQFYCHCDDCQATSGGAYIGVAVYPVDAVKIMQGELTTWTLKSLPRQRCAVCGTHVMAEVPGLAQVGIKANLLPKGEFKPDFHLHCRYAVLPVKDDLPHFKDLPASFGGTDGTSNW
>NZ_CP021983.1|WP_080808040.1|3038677_3039538_+|class-D-beta-lactamase
MICVPKWFGGLVAGSVMTIVAQPALAEAGVQPVTPLLAQQEVPAQVDFAPHFQDLGIEGSIIIYDLNLNQTYQHNSERNSTPYLPGSTFKILNSLISLEAGVIDNDLAILTWDGVERIVPAWNRDLNMRTAFPLSAVWFYQVLARRVGHDRMQQSVAEAGYGNQDIGSAEDIDTFWLTGDLRTTPEEQIDFLRRLYNDDVPFSEDVIALGKDIMIVEQTPDYTIRAKTGWVGFGEPDQEQIGWYVGYVEQADNVYFFATNIDIRDEDDPAARVEVTRRCLETLQLL
>NZ_CP021983.1|WP_080808043.1|3038378_3038624_+|hypothetical-protein
MQGDVGYEIRNLNLSVGDDVAFSNSINQMSGVKTTGEKFDIWVRMTVGYRKQDGRWRVVHEHISVPFYMNGSFKAAVDLEP
>NZ_CP021983.1|WP_080808049.1|3037222_3037645_+|YciI-family-protein
MKVVVLVKATPDSEAGVMPTEAILAEMGQFNEELVKAGVMLAGEGLHPSSKGVRVQFSGKNRTVIDGPFTETKELVAGFWLWQVQSMAEALDWIKRSPFQDGEVEIRPIFADEDFGEAFTPELREQEERLCTEMEKQKSA
>NZ_CP021983.1|WP_088430162.1|3045309_3045891_-|hypothetical-protein
MGGLGGQIAGKSLQITYGFLAQQWVGWANSLPLLLATVETLGLPTNPCEQGKQKGRRQKAEIKAEGRRQKAEGRRQKQWVGWANSLPLLLATVETLGLPTNPCEQGKQKGRGQLVLYDFQSGSAKRVAAPQGQRSRWHSLPGGHREGRNKGRRQKAACPVRVAAPQGQRSRWHSLPGGHREGRRQKAASNRGL
>NZ_CP021983.1|WP_080808017.1|3046033_3046468_+|peptidylprolyl-isomerase
MAQAQKGDTVLIHYTGKLTDGTVFDSSVERGPLQFDIGAGNVIPGFETAVIGMSPGDSKTETIGSDQAYGPHRDEMVVVVDRQQIPDEIPLNIGQQLQLQGPEGRPPLPVLVTEVSDGKVTLDANHPLAGEDLVFDIELVDIVS
>NZ_CP021983.1|WP_080808014.1|3046464_3047424_-|EamA/RhaT-family-transporter
MLGVAIVLLSACFFCVQNVIVRVLFNQQVVLGIGVTGGFVPPTLENSFLLLVMRMVLVVPLMAGLAAGFYPATWKDIRQLGSSHQRRPLLQAIAGGGLMFLYLALLYVAIGLLPAGIALTLFFSYPVFTALFSWGVFGTRPSRYRWVIMGLILLGSYLTMPAASGGDSQSWLGVLFGLAAGVAYALYTVNAQKSFDVVHPFPFTWISFATTLALSTLSLSLGRGNVSQVPAAAWGPLWIGGLLSALVTFAGHVLNNLGIRGIGATAAAMIGASNPALTVVLAWVAIQEAITPVQLSGVILVTASVAMLAREHRPRGRES
>NZ_CP021983.1|WP_080808011.1|3047472_3049308_-|hypothetical-protein
MGNRYQDLIEGIVTAILKGQVRSKEQIYQRLQSEVEIGTGELFERCLQDRFDAIEQVLATDPDELQQAKATRQQRALKTLQSEWERWQQANQVQAILSQTLARLTSAEPQERLPRLLQALDINQPHPLSRDQVRQLGRQLQTAASPEDAAPSLQDLARGLQGGLDTWQQLQGHAISWIYDQSQPSLGFDNQRQRGPWPHWAQVIKQHPLHSIFADLAQHQTITATGIPHPLSVCDWLALAWVLQRLQLGLVSWFDQQPYDSRAGKRLSIATYLTFAVVWSQLRARLQHLGQSNLVQGCFQMTLQVLYQFAQQDYFPLYGGLFAALSGESLQVLLDYLDQPLKQEPNTAGKARILTLLGYSQRALGRYTVAQQFHHRALDSARQAGDTRCEIANLNHLSRTAVMAEQFQQAIDDSQRALIMARQAGDRLGEANALANYGYSQVCQARQQSLQPQQYESTLTYLQQGLALGQQLGDRPSQALCANSLGMAQVMLGRYDAALESLEQGLRVAHDIGDQFLQGMNYAYMASAYRGLDTLDMAIFTGCLAMYLLHQIDSEHWRQPAGVVSILYGQLGAGRFTDTLANYRSGFLKQIGVDGYDYLPTLLADYRQSLD
>NZ_CP021983.1|WP_080808008.1|3049769_3050351_+|pentapeptide-repeat-containing-protein
MRRDYSIPLSLLSVLLLAGAAPAEAPPSELRSTNVRRLLITNSCSRCDLAGVDLSGAHLIGADLREADLTGANLTGANLEGADLTAANLTGANLTGSFLTNASLVRADLDNANLTQAQLYYVNVTGASMENLNLAEATVVGTPISIGGSLDPSQANTAPTVRPHELWELEPPREPGAFPHDLLDVPVQIMPQV
>NZ_CP021983.1|WP_088430164.1|3050360_3050756_-|hypothetical-protein
MWVFHNRPAAGTQSTPTLVQLFPLSYLYLQTLQRQPWPCRCRPQITLDSNRLFSAVFQQQGFIRLYRACAESLASENASRLAAMQIAEKNIEERLAELKTTFQQQRQDTITDELLDIISGFEALAPPAHGG
>NZ_CP021983.1|WP_088430166.1|3050836_3051079_-|hypothetical-protein
MARLRTAMAAVGRALDRAQLVFGSRMADALRLAHHPLEECLSVPGSIVGITPLVQQIVMQLVVHGINKPTIESAGILPAT
>NZ_CP021983.1|WP_080808000.1|3051123_3051372_-|hypothetical-protein
MNTQDTARQHLAQQRQKQHHLQQSMQERSEEELTDLSDAAIQAEARESLTNQRHHDHQLEDTMTSRSAAEIEPQASPESTAE
>NZ_CP021983.1|WP_080807998.1|3051681_3052509_-|response-regulator
MVQRLRQNLNCDSSHAVVSAAIASAPQLWVVGATAPFNQRVSAAALAMGLRCTVVATPSQALALLRTQLPAGVLLWIDQATLDIGMTLLDALTDHGEHIPSLLVTDTQDFQQRLQMVQRGADRLLLPSISPQHALEIIQESLHTTGAAHKVLILDDDSQVLELLQAVLSPWGFQLTTLADPTQLLPTLEAVRPRLLVLDVEMPQINRLEICRVLRADDRWRQLPILILTVHEDIPTQQQAFQVGVDDFISKPVMAADLANRILNRLQRVQAQESS
>NZ_CP021983.1|WP_088431687.1|3052753_3053521_+|protein-tyrosine-phosphatase
MLEPIDVVLQLQSPHFPEELQVQVWTNLPTRFNGDGTWYAIEIPYLETSHGHYRFQGSLRPTSPGDFELTYRVSHRANPEMMQWLAGPRDNAVLRVAPPAPDQEWTQRPNPTEIMPGVYVGNFMAASQAEALGFDAVLNMAEELNPTVGNGIAYGKLACRDGAGHPIPEDHLQAAVAWIEHQLAQGKQRVLVHCRAGIGRSGSVGVAYCFYKHPQWSYAQALDYVWSKKPDVYPHRQLQESLERLFPRAGSRSNK

Crispr_ID: NZ_CP021983_24

• CRISPR_ID: NZ_CP021983_24
• CRISPR_location: 3278981-3279075
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP021983_24

Consensus_repeat	Method
CAACCCTTCTTAGGGATTGAAAC	CRISPRCasFinder

spacers of NZ_CP021983_24

>24.1|3279004|49|NZ_CP021983|CRISPRCasFinder
CAACTGGATCAGCATCTGGCAAAACGCCCCGGCGTGTTCCAATCAACAA

CRISPR arrays and Neighbor proteins around NZ_CP021983_24

CRISPR arrays

The CRISPR arrays of NZ_CP021983_24

>merge|NZ_CP021983|24|3278981-3279075|CRISPRCasFinder
CAACCCTTCTTAGGGATTGAAACCAACTGGATCAGCATCTGGCAAAACGCCCCGGCGTGTTCCAATCAACAAAAACCCTTCTTAGGGATTGAAAC

>NZ_CP021983|24|25|3278981-3279075|CRISPRCasFinder
CAACCCTTCTTAGGGATTGAAAC	CAACTGGATCAGCATCTGGCAAAACGCCCCGGCGTGTTCCAATCAACAA
AAACCCTTCTTAGGGATTGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_088430261.1|3279666_3280242_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP021983.1|WP_080807021.1|3273297_3273840_-|hypothetical-protein	unknown	unknown	gnl|CDD|375593
NZ_CP021983.1|WP_080807029.1|3277938_3278334_-|hypothetical-protein	unknown	unknown	gnl|CDD|376574
NZ_CP021983.1|WP_080807035.1|3283482_3285018_-|MFS-transporter	unknown	unknown	gnl|CDD|273322
NZ_CP021983.1|WP_080807025.1|3275309_3276143_-|ATP:cob(I)alamin-adenosyltransferase	unknown	unknown	unknown
NZ_CP021983.1|WP_080807041.1|3289470_3290544_+|hypothetical-protein	unknown	unknown	gnl|CDD|168934
NZ_CP021983.1|WP_080810192.1|3264167_3264869_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213191
NZ_CP021983.1|WP_080807030.1|3278507_3278930_-|hypothetical-protein	unknown	unknown	gnl|CDD|225995
NZ_CP021983.1|WP_080810188.1|3268259_3270650_-|DUF3893-domain-containing-protein	unknown	unknown	gnl|CDD|372482
NZ_CP021983.1|WP_080807023.1|3273826_3274903_-|hypothetical-protein	unknown	unknown	gnl|CDD|380126
NZ_CP021983.1|WP_088430259.1|3276187_3276532_-|hypothetical-protein	unknown	unknown	gnl|CDD|376574
NZ_CP021983.1|WP_080807037.1|3285166_3286753_-|ferredoxin--nitrite-reductase	unknown	unknown	gnl|CDD|236572
NZ_CP021983.1|WP_080810190.1|3267204_3267639_-|hypothetical-protein	unknown	unknown	gnl|CDD|275209
NZ_CP021983.1|WP_080807034.1|3281093_3283298_-|nitrate-reductase	unknown	unknown	gnl|CDD|239155
NZ_CP021983.1|WP_088431699.1|3280522_3280987_-|nitrate-reductase-associated-protein	unknown	unknown	gnl|CDD|378232
NZ_CP021983.1|WP_088430263.1|3287250_3288354_+|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|224331
NZ_CP021983.1|WP_088431701.1|3288461_3289373_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NZ_CP021983.1|WP_080807109.1|3290540_3291134_-|molybdenum-cofactor-guanylyltransferase	unknown	unknown	gnl|CDD|235063
NZ_CP021983.1|WP_080807020.1|3270652_3273301_-|hypothetical-protein	unknown	unknown	gnl|CDD|224120
NZ_CP021983.1|WP_080807042.1|3291300_3291948_+|DUF3386-domain-containing-protein	unknown	unknown	gnl|CDD|371771

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_088430261.1|3279666_3280242_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.77354e-17
NZ_CP021983.1|WP_080807021.1|3273297_3273840_-|hypothetical-protein	gnl|CDD|375593	pfam18155, pPIWI_RE_Z, pPIWI RE three-gene island domain Z. Poorly-understood domain observed N-terminal to DinG-type helicase, which is part of a conserved three-gene island also containing a REase domain and the pPIWI_RE module. This three gene island is predicted to form a conflict system which targets R-loop formation of invasive plasmids during plasmid replication.	5.80834e-05
NZ_CP021983.1|WP_080807029.1|3277938_3278334_-|hypothetical-protein	gnl|CDD|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	7.50115e-36
NZ_CP021983.1|WP_080807035.1|3283482_3285018_-|MFS-transporter	gnl|CDD|273322	TIGR00886, Nitrate/nitrite_transporter_NarK, nitrite extrusion protein (nitrite facilitator). [Transport and binding proteins, Anions].	1.74022e-55
NZ_CP021983.1|WP_080807037.1|3285166_3286753_-|ferredoxin--nitrite-reductase	gnl|CDD|236572	PRK09566, nirA, ferredoxin-nitrite reductase; Reviewed.	0
NZ_CP021983.1|WP_080807041.1|3289470_3290544_+|hypothetical-protein	gnl|CDD|168934	PRK07394, PRK07394, hypothetical protein; Provisional.	0
NZ_CP021983.1|WP_080810192.1|3264167_3264869_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213191	cd03224, ABC_TM1139_LivF_branched, ATP-binding cassette domain of branched-chain amino acid transporter. LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.	4.80173e-115
NZ_CP021983.1|WP_080807030.1|3278507_3278930_-|hypothetical-protein	gnl|CDD|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.08032e-13
NZ_CP021983.1|WP_080810188.1|3268259_3270650_-|DUF3893-domain-containing-protein	gnl|CDD|372482	pfam13111, DUF3962, Protein of unknown function (DUF3962). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 233 and 796 amino acids in length. There is a conserved FSY sequence motif.	8.19088e-23
NZ_CP021983.1|WP_080807023.1|3273826_3274903_-|hypothetical-protein	gnl|CDD|380126	pfam18154, pPIWI_RE_REase, REase associating with pPIWI_RE. Restriction endonuclease (REase) domain family, found in a conserved three-gene island that also contains a DinG-type helicase and the pPIWI_RE module. This three gene island is predicted to form a conflict system which targets R-loop formation of invasive plasmids during plasmid replication.	1.011e-10
NZ_CP021983.1|WP_088430259.1|3276187_3276532_-|hypothetical-protein	gnl|CDD|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	5.0793e-21
NZ_CP021983.1|WP_080810190.1|3267204_3267639_-|hypothetical-protein	gnl|CDD|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	1.2945e-39
NZ_CP021983.1|WP_080807034.1|3281093_3283298_-|nitrate-reductase	gnl|CDD|239155	cd02754, MopB_Nitrate-R-NapA-like, Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol oxidation via a membrane-anchored tetraheme cytochrome. Members of the MopB_Nitrate-R-NapA CD belong to the molybdopterin_binding (MopB) superfamily of proteins.	0
NZ_CP021983.1|WP_088431699.1|3280522_3280987_-|nitrate-reductase-associated-protein	gnl|CDD|378232	pfam09655, Nitr_red_assoc, Conserved nitrate reductase-associated protein (Nitr_red_assoc). Proteins in this entry are found in the Cyanobacteria, and are mostly encoded near nitrate reductase and molybdopterin biosynthesis genes. Molybdopterin guanine dinucleotide is a cofactor for nitrate reductase. These proteins are sometimes annotated as nitrate reductase-associated proteins, though their function is unknown.	1.65407e-87
NZ_CP021983.1|WP_088430263.1|3287250_3288354_+|HEAT-repeat-domain-containing-protein	gnl|CDD|224331	COG1413, COG1413, FOG: HEAT repeat [Energy production and conversion].	1.40598e-16
NZ_CP021983.1|WP_088431701.1|3288461_3289373_+|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	9.75856e-52
NZ_CP021983.1|WP_080807109.1|3290540_3291134_-|molybdenum-cofactor-guanylyltransferase	gnl|CDD|235063	PRK02726, PRK02726, molybdenum cofactor guanylyltransferase.	1.63967e-89
NZ_CP021983.1|WP_080807020.1|3270652_3273301_-|hypothetical-protein	gnl|CDD|224120	COG1199, DinG, Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair].	0.000251784
NZ_CP021983.1|WP_080807042.1|3291300_3291948_+|DUF3386-domain-containing-protein	gnl|CDD|371771	pfam11866, DUF3386, Protein of unknown function (DUF3386). This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are about 220 amino acids in length.	1.60271e-118

Protein sequences

>NZ_CP021983.1|WP_080807030.1|3278507_3278930_-|hypothetical-protein
MQPLLTKLLNLPGVEVEDYYDLGDQLILDVEAQTDRATCPRCHQDSHHVHQNHPYLVRDLSISDRTVLLRVNRRQFKCLTFGKPFSEPLNFVGKRRKHTDRFCKAMVQQLIHSDAHNVAMNNGLTDEEVASIVKYIAKKT
>NZ_CP021983.1|WP_080807029.1|3277938_3278334_-|hypothetical-protein
MLEHILEVSIDLSGNYRSFVNKYLPNADIVADRFHIMKLVNDELNRTRNQLKREANAAPDTPENKVVRQALKQSKYALLKPEDNLTEVQQNKLNEIRDASPKLAEMHGLKEQFRTIFETASKCRAIACKSA
>NZ_CP021983.1|WP_088430259.1|3276187_3276532_-|hypothetical-protein
MTCLALDTWVDKLFCQVRLIQNKCDCPASKWSEALFELLDWMVDAETYFNGSVGTLCRWFGEVLNYFENGTTNGIVEGINNRLKLIKRLGFGFSNFDNFELRCLICWNIDMNLA
>NZ_CP021983.1|WP_080807025.1|3275309_3276143_-|ATP:cob(I)alamin-adenosyltransferase
MSTDTGAESFRFQSLRRVFVDWNLRRFGQDKGLSLNSAKTILGQVSELDVAKKVDELKADLLKIRRTIFETSGGVTFEEEEYYEKLTSEQVEYLLNLLKEADIDESDAELVLALLRDHGTDVLSRMNVFLERFPSLSKSIYHFSKYVDDRESLASLILNFIRAGENITEDQLFWMGKLSEDYLADTSEYSSILLELYEHPNATLISRAKILEIPEQRFGMIELREEHLRTGKSDWLAWSAAVGTRGATAISRNHTLTYFSKASPMNKIIGDCIRSLP
>NZ_CP021983.1|WP_080807023.1|3273826_3274903_-|hypothetical-protein
MAVEHAEIGFAYLLKAIALSPDGRASSGLPLRETEHALDHFAVAAFKQGVHPPGNWSELVREVINEPYCEWPSYLQGDLLEPTDRLIQFGKIPDQTIKVSAWVSELADDEDYVALRNSPDEIEENQFFNEMRSYCQSQEDPQRLYVELRRYLVSSVSKTEDEMIDFLSGKPKELRGLIDKAYYIADTAPSDFACKQCGAPSIDCKPHPQCRDCISMQSIEVRKYESGEKVLRGRIASAFYFRSAIDVNLFEEFKRTLSTCELWPNLDLDGDVSVKFPNGDYWIFDCKDYLYPRSLIRKVSKERFTRDCDRFIYVIPDRVGEVYLQQARDALPNHNFLFFNRAIASVKDKVRRIRSART
>NZ_CP021983.1|WP_080807021.1|3273297_3273840_-|hypothetical-protein
MPGRDLSKLESVIEVFADEEVIESPRLTAKLEACLWAFHHLYPNEPIDLLRFVVSGNVHQIDATKPTQLHRSLQVIGGPFLTWEYARRSVLSPYFELPERVRGFSIKDDSVHLQLGECQIEQNSQAILPGRFDIYKDCMSKPIPLKETHVKRRGNGIYLLRSYKHDDGQLERIEIEGFPL
>NZ_CP021983.1|WP_080807020.1|3270652_3273301_-|hypothetical-protein
MNLIQIPPQRSANPELSVTFDQLINFTGELVSQQRLPKYYLEELHNLKLSQFPKMGETETLTFNQVVALHGPAGTGKSILIRLVTLYFANKSSYRIAIISPTITTALSTAQKLWPYLSHGKQDIAVIVGRSNRNRYRKDFLETPESSNLEHIGHDVLDYSCALAGLSEHVDRENPPCLDLKYRSERGEPNCHCPFIDNCSRHRQEQNLAQSSVLITTPEGALLSNIQLANQPMPVLEYITKTFNICFIDEADSAQQRIQSRLSPDKDLREWLEEVSSYQDVIRRKRSRNLKRLSVAGLNNDLNQASTIFDWLIGYLSRRPEACTSLEKMSFFNATFLQLNWIKKTHEFIKEIQSGWSNEDYQAIKEQLFPLLKKGVKSTSDDPFSIATSQIFYEEDFDGSPNNIIAVKLSQALSQYKSFQSLEEAEQRLFVDYFLIILAVNALLVLLHDADRGLTASEMAISIKRDAPQPALSSNPKYLENIFPRLITGRAAGLVLDRGINHDDLNLLYFSLLFSGPDLVANLSKLYELDDYAGCHFVLATATGWLPDGRSIYHLRTDGYLLQRQDRQHGQISLHYHPFYKSDGNPIFVSGLETEDKLAAISEITKRLFEGGSASIVEQDLQQYPEARRRALLTTNSKTQCWAVWEALEFLGQGDRCKVLVGDNDNLDSFDPRKRAACLRRRHAERFATIPGVDVLIAYFQGVSRDINIVPPGSREAAFCALYSLVRPHAHPTDLQISIELFLVSLFETDQRLPDILARRAKLLAEKDPPQRFNLLDQCRYYARIADRLIDQAFKRQIRYLPQASKSFMNNILLNRWWVEDIGQLWPRIMRGQVDATVRLCDAAYSSYLGDAIDRAKQLQKDPKAVFLWSQGIQALLNVKGF
>NZ_CP021983.1|WP_080810188.1|3268259_3270650_-|DUF3893-domain-containing-protein
MKISLKAAALQLNPNQLRDSYYSLTFPADLKQILLVDYSRDRSQRGNHPISLPGYQFKALVNASIPQVVCADGRLPTDKPFLFCLEHVPEERVKRLLKHWVRETFTLPKKRGQKSAVEQDITASLAAIEQASFRWQEHQLSPEDWELSVNSTAQPRDSCLFEIIPSIVVSQIVKSNLSFPEFSSQFQSIKFLPALEIASSLFQKPQFCITDVFYSKKGNPYSFMIHPRLLQIPGQPQIYLPLDFGVRRYLSKPYTRKKLPESFSVMIYTPNGVCTAKINEVRCWENNLAELLSKFDYDSVPSADELLSNPLGWSNPDLKLRFLVVNREGREKFQDVTAGVTPNDLAHLFDTIAPILQPGFEYFEPKIIDKGNSKFSKLRPSSCPDLIHYVDFQDIGKALEHEAKKLKFNLIKETDPGLVEMCNPIPVTPEDNWQQRNQDRDQVIAERVKALPERCNETKVLILPIYPENYFKQRPQEDPYNSLEEFLPDRNLLIKRLTVPTGEDEVEEISHKCKATLLTMKCRLGYHDGLIPEALKAYELPLDLQTIGIHLHKLSNGNYLPVAVKLDAKGILTGRTAISTWQPLREFIPYVQAATTIEGCKGLKLKNLTSSFFRELADSTISTLILPYSNNTRQALNGLYDSKFGADGTISLLNQNGELELFKLPNNCRVIRCRDGGELPQATLWNNDKNQPARGRAIAQFGDNSYLLIRPKASTDQSNSQESMLRPYEHRSGKVIQPKTKTTAKKITLVEANPLLQPNDKTLHWLGYLQYLQRIAPQYDNFLHLPLVLHIPSAFL
>NZ_CP021983.1|WP_080810190.1|3267204_3267639_-|hypothetical-protein
MATNETEKVRQLQRSLYRKAKQEPQTKFYSLYDKLCREDVLWEAWRQVRLNQGAPGIDGVSIREIEENGQAVTLIQQLQAQLRKQTYHFDAVRRVDIPKPQGGTRPLGIATVKDRIVQTAMKLVLEPIGSPGIIMQQQEKNASR
>NZ_CP021983.1|WP_080810192.1|3264167_3264869_+|ABC-transporter-ATP-binding-protein
MSLVLNNVHSGYGGVDILKGVNLRVAPGEIVVIIGPNGAGKSTVLKSLFGLATVRQGKIFFQGQEITRLRCDRMVRRGICYVPQTNNVFASLSVQENLEMGAFVRDDDYRPQLEQVYELFPPLRKKHQQPAGTLSGGQRQMVAMGRALMVQPQLLLLDEPTAGLSPLFVQQIFDIIGTINQLGVSLLIVEQNAKQALQMADRGYVLTMGQNRYEDTGQNLLNNPQIADMFLGG
>NZ_CP021983.1|WP_088430261.1|3279666_3280242_-|TetR/AcrR-family-transcriptional-regulator
MARTQSSRSSARDRILATAADLFYREGVQNVGIDRIIAESGVAKMSLYNHFKSKDALIAAWLLQQDEAWRSWFQTRVEQSATEPLDRLLAMFDVLEEWFNQPDFRGCAFLNSTVELVDPNHPGYQVSMQHQQLTFDYILGLVQAANLSDPEGITRQVMIIMEGTVVIAMLQHCSGIACCGKQILSTLLEHQ
>NZ_CP021983.1|WP_088431699.1|3280522_3280987_-|nitrate-reductase-associated-protein
MSEKPVFFAFEADFVESLRCIPMQVRFKLDTCGIKLKLDQWHRFDAQERYSLAQWPCSTEAEIQTYRTYLQQLVLQHTQTPAKDLAVDPEPPWHQPGAVPVQTQEQAQALGITIPVDKWANLTPLQRFALYKLSRPGHENRNFLPALQEFKLAE
>NZ_CP021983.1|WP_080807034.1|3281093_3283298_-|nitrate-reductase
MTDATKTLCPYCGVGCGLEVLPPARRGRPVQRDSQGFPLWQTRGDRNHPSSKGQVCVKGATVGEALNKDRLKHPMLRSSLEQPFQQVSWDEALTVLTDKIQTVRQQLGPEALCMYGSGQFQTEDYYIAQKLMKGCLGSNNFDANSRLCMASAVAGYLQSFGSDGPPCCYADLELTDCAFIIGSNTAECHPIVFNRLRKHHKKNRQVKLVVVDPRRTETAKDADLHLAIKPGSDITLLNGMAHLLLRWCKLDALFIEECTHGFTDYAAVVEQYPPEKVAQACGITVPELETATRYWAEAERVLSLWSMGLNQSAEGTAKVRTLINLHLMTGQVGKPGAGPFSLTGQPNAMGGREAGGLAHLLPGYRSVANPEHRQVLEQAWQLPAGSIAAAPGLDTWEMVRALERNQVGLLWVAATNPAVSLPDLERAQAALRRSPFTVYQDAYYPTETAAYAHLLLPAAQWGEKTGVMTNSERVVTLCPAFCPPAAEARPDWEIFAEVGRRLGFTEQFAFQSAAEVFTEFVQLTRGRVCDMTGLSHECLAPGPKQWPYPADDPSQAMDKRLYTDLRFPTPDGRARFASFHSRGLAEPPSPEFPFVLTTGRLYGHWHTQTRTGRIEKTRTMYAEPLLEMNPRDAQELRLQSGQWVEVRSRRGQVRVKLRVTQTIRRGTVFLPMHWGVLWATAAECNALTHPEVCPVSLEPELKACAVHITPVSDTVTAPMQQAHPEAMPVGASPL
>NZ_CP021983.1|WP_080807035.1|3283482_3285018_-|MFS-transporter
MLAEMWSLRGRYKILHMTWFAFFLSFVVWFNLAPLATAIQEEFGLDAGQIRTIAICNVALTVPARIIIGMLLDKYGPRLTYSLLLIYAAIPCIAFAAAQNFSQLVAARLALSIVGAGFVIGIRMVAEWFPPREIGLAEGIYGGWGNFGSAASAFTMVGLATFLSFFPGAFQVADGPLLNWRMAIAATGIIAALYGILYYFSVEDTPPGKPYQRPHSTRGVEVTSQRDFWFLMAMNLPLVGILAVLAWRLKGIGFLNDGTFAITLIVLAGLYLYQAYNCWHVNQELLTGRKRYAPEDRYPFSQVALLELTYIVNFGSELAVVSMLPAFFELTFGLSKQAAGMIAATYAFMNLMSRPGGGLISDRMGSRKMTMSVLLLCMGIGYLMMSTVTNAWLLPLAIALTMVCSFFVQAAEGSTFAMVPLVKRRITGQVAGNVGAYGNVGAVAYLTIYSLLPEGVIGDRIFFQVLGVAGVVVAMLCFFFMKEPRGSFAEFHEGEEAYVTPSTPAPLPVKE
>NZ_CP021983.1|WP_080807037.1|3285166_3286753_-|ferredoxin--nitrite-reductase
MVSASKKTGTKLNKFERYKAEKDGLAVKDELEEMAQMGWEAVDETDLTQRLKWLGIFFRPVTPGKFMLRLRMPNGVLNSHRLRVLATIVQRYGDDGSADITTRQNLQLRGVRLEDIPDIFQRLKHAGMTSVQSGMDNVRNITGSPVAGLDANELIDTQGLIRKVQDMITGNGDGNYAFTNLPRKFNIAIEGGRDNSVHAEINDIAFVPAYREEQLGFNVLVGGFFSARRCAAAIPLDAWVPPDDTVVDVCRAILEVYRDHGPRANRQKSRLMWLIDDWGLDRFRSTVEAAMGRPLARAAATDEIDWDKRDHIGVHPQKQPGLNYVGLHVPVGRLQADDMVEIARLAEVYGNGEIRLTVEQNLILPNIPDSRLPVFLQEPVLQKFSLEPTPLVRSLVSCTGSRFCNFALIETKQRALALAQSLDQALAVPQPVRIHWTGCPNSCGQPQVADIGLMGTKVRKDGQAVEGVDIYMGGKVGKDAQLGQCVQKGVACEDLPQVMQQLLIDHFQAQPREADNQSQHNGHTVTAL
>NZ_CP021983.1|WP_088430263.1|3287250_3288354_+|HEAT-repeat-domain-containing-protein
MFSDQPAAIATAIDTLLAGDFQDRWQVAKQFSEIGVAALPALLELMQDEALDWEVRWFVTRILGNFESSTAIEALIQLLLHSDDDDLRQMAAAALAQIGVAAVTALAPLLQYPVQRPLVVQALARIPHRAVIPLLMQVVRDEQASVRATAMAALGHFSQPDLLPVLMMALDDREATVRAEAVRGLGRWSATQMQPAHIARLAQGLTDVDDNVAQLTANTLGRLGTPPAITALITALQGPPPPVHRQVALVRSLMRCLTEGGLSCLMERWTTLALPAQAEIISGLNHLEDRALQEQAAMTLCHYLRVGIVPAPLWPHLILTLGYLRHPDALPLLQQLLQDDDPRVRMHASEALRQLNSQGSSSAPEAP
>NZ_CP021983.1|WP_088431701.1|3288461_3289373_+|LysR-family-transcriptional-regulator
MRLEHLQAFLSVAATGSFQKAAQECNVTQSTISRQIQTLEAELGTSLFHRTSQAKLTIAGDCLLPQARKISQAWAQAVQEIDTLMAGKQPELCVAAIQSVCAYFLPPILQQFCQVYPEVQLRVTALGSDRSLKVLRDGLVDVAIVMENPLLTTGPEMVVDVLYEEPIQVLMAAEHPLSRCSAVPWAELVHRPQVMFKDGYGMQRLVKEQFQRYGVEPKTVLELNTLEAFRGIVRQGQLIALLPQSALIDSQQDETLAIRPTEDPPLVRRVLLVTTQDRVDIPPIQRFCALVRGANQRIISAVA
>NZ_CP021983.1|WP_080807041.1|3289470_3290544_+|hypothetical-protein
MSHQFRELLKKVGSGTHTSKQLTRQEAALATRMMLQQEATPAQIGAFLIAHRIRRPTSIELAGILDAYGVLGPRLSSQPSSKAAMVFGLPYDGRSRTAPAQPLVALLLATMGCPVVLHGSNCMPTKYGLPLIDIWQGLGIDWMGLSLAQVQAVFQATGVGFLYLPEQFPLAQGLVPYREQIGKRPPMATAELMWCPYAGDACLVSGYVHPPTEGLLTGTLDLQGIPHYLTVKGLEGSSDLPRARTAIIGIHRHGSEERLLLHAREYGLGDSSEFPLSEPLVYIEQLQQLLRGAPSPLMPVALWNGGFYLWQSGLCSSLEAGIAQAETLLVSGQVQETVTRLCDRIAASRRRDPLILR
>NZ_CP021983.1|WP_080807109.1|3290540_3291134_-|molybdenum-cofactor-guanylyltransferase
MSVLILAGGQSRRMGQDKALLPWQGDTLLGRTCRLALTCCPTVLVVTPWPQRYRSQLPQAVCFITESHPPGTPPPGPLMGFLRGLPQVSTEWVLLLACDLPRLSEALLQQWASQLDQVSPQMLAWVPRTEQGWEPLCGFYRRGCLQSLQQFAAGGGRSFQRWLDQEAVQPLTLPHAAVLWNCNTPQDWATIGGQDFC
>NZ_CP021983.1|WP_080807042.1|3291300_3291948_+|DUF3386-domain-containing-protein
MVGTQTSARDLFRSAYENRYTWDANFPGYTAKVTYTHNGQTVTGQVRVGADLKAQVTDITDETAQKAVHNQLWETAIHRVRRAFEDTHGQNSFQYGQTLADGGIEILMGGKADGDRYHLRDNQVTMVHRHIHGVVVTIHTFSSHNTGEGYLSHRYDSIYHDPKTGEPRGGKSVFEDDYERVGDYFILSRRHVVTDTDHGPDTQTFEFANIELLSQ

Crispr_ID: NZ_CP021983_23

• CRISPR_ID: NZ_CP021983_23
• CRISPR_location: 3276075-3276171
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP021983_23

Consensus_repeat	Method
GTTCCAATCAACAAAAACCCTTC	CRISPRCasFinder

spacers of NZ_CP021983_23

>23.1|3276098|51|NZ_CP021983|CRISPRCasFinder
TTAGGGATTGAAACCTGAATGATTCCGCCCCTGTATCCGTACTCATAGGGT

CRISPR arrays and Neighbor proteins around NZ_CP021983_23

CRISPR arrays

The CRISPR arrays of NZ_CP021983_23

>merge|NZ_CP021983|23|3276075-3276171|CRISPRCasFinder
GTTCCAATCAACAAAAACCCTTCTTAGGGATTGAAACCTGAATGATTCCGCCCCTGTATCCGTACTCATAGGGTGTTCCAATCAACAAAAATCCTTC

>NZ_CP021983|23|24|3276075-3276171|CRISPRCasFinder
GTTCCAATCAACAAAAACCCTTC	TTAGGGATTGAAACCTGAATGATTCCGCCCCTGTATCCGTACTCATAGGGT
GTTCCAATCAACAAAAATCCTTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_088430261.1|3279666_3280242_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP021983.1|WP_080810190.1|3267204_3267639_-|hypothetical-protein	unknown	unknown	gnl|CDD|275209
NZ_CP021983.1|WP_080807029.1|3277938_3278334_-|hypothetical-protein	unknown	unknown	gnl|CDD|376574
NZ_CP021983.1|WP_080810198.1|3261435_3262659_-|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|380569
NZ_CP021983.1|WP_080807021.1|3273297_3273840_-|hypothetical-protein	unknown	unknown	gnl|CDD|375593
NZ_CP021983.1|WP_080807037.1|3285166_3286753_-|ferredoxin--nitrite-reductase	unknown	unknown	gnl|CDD|236572
NZ_CP021983.1|WP_080807020.1|3270652_3273301_-|hypothetical-protein	unknown	unknown	gnl|CDD|224120
NZ_CP021983.1|WP_088430259.1|3276187_3276532_-|hypothetical-protein	unknown	unknown	gnl|CDD|376574
NZ_CP021983.1|WP_080810188.1|3268259_3270650_-|DUF3893-domain-containing-protein	unknown	unknown	gnl|CDD|372482
NZ_CP021983.1|WP_088431701.1|3288461_3289373_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NZ_CP021983.1|WP_088431697.1|3259499_3260456_+|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl|CDD|119323
NZ_CP021983.1|WP_080807034.1|3281093_3283298_-|nitrate-reductase	unknown	unknown	gnl|CDD|239155
NZ_CP021983.1|WP_080810194.1|3263391_3264171_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213186
NZ_CP021983.1|WP_088430263.1|3287250_3288354_+|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|224331
NZ_CP021983.1|WP_080810199.1|3260830_3261295_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NZ_CP021983.1|WP_080810192.1|3264167_3264869_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213191
NZ_CP021983.1|WP_080807035.1|3283482_3285018_-|MFS-transporter	unknown	unknown	gnl|CDD|273322
NZ_CP021983.1|WP_080807030.1|3278507_3278930_-|hypothetical-protein	unknown	unknown	gnl|CDD|225995
NZ_CP021983.1|WP_080807023.1|3273826_3274903_-|hypothetical-protein	unknown	unknown	gnl|CDD|380126
NZ_CP021983.1|WP_088431699.1|3280522_3280987_-|nitrate-reductase-associated-protein	unknown	unknown	gnl|CDD|378232

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_088430261.1|3279666_3280242_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.77354e-17
NZ_CP021983.1|WP_080810190.1|3267204_3267639_-|hypothetical-protein	gnl|CDD|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	1.2945e-39
NZ_CP021983.1|WP_080807029.1|3277938_3278334_-|hypothetical-protein	gnl|CDD|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	7.50115e-36
NZ_CP021983.1|WP_080810198.1|3261435_3262659_-|amino-acid-ABC-transporter-substrate-binding-protein	gnl|CDD|380569	cd06346, PBP1_ABC_ligand_binding-like, type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.	1.37972e-125
NZ_CP021983.1|WP_080807021.1|3273297_3273840_-|hypothetical-protein	gnl|CDD|375593	pfam18155, pPIWI_RE_Z, pPIWI RE three-gene island domain Z. Poorly-understood domain observed N-terminal to DinG-type helicase, which is part of a conserved three-gene island also containing a REase domain and the pPIWI_RE module. This three gene island is predicted to form a conflict system which targets R-loop formation of invasive plasmids during plasmid replication.	5.80834e-05
NZ_CP021983.1|WP_080807037.1|3285166_3286753_-|ferredoxin--nitrite-reductase	gnl|CDD|236572	PRK09566, nirA, ferredoxin-nitrite reductase; Reviewed.	0
NZ_CP021983.1|WP_080807020.1|3270652_3273301_-|hypothetical-protein	gnl|CDD|224120	COG1199, DinG, Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair].	0.000251784
NZ_CP021983.1|WP_088430259.1|3276187_3276532_-|hypothetical-protein	gnl|CDD|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	5.0793e-21
NZ_CP021983.1|WP_080810188.1|3268259_3270650_-|DUF3893-domain-containing-protein	gnl|CDD|372482	pfam13111, DUF3962, Protein of unknown function (DUF3962). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 233 and 796 amino acids in length. There is a conserved FSY sequence motif.	8.19088e-23
NZ_CP021983.1|WP_088431701.1|3288461_3289373_+|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	9.75856e-52
NZ_CP021983.1|WP_088431697.1|3259499_3260456_+|branched-chain-amino-acid-ABC-transporter-permease	gnl|CDD|119323	cd06581, TM_PBP1_LivM_like, Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivM forms a heterodimer with another TM, LivH, to generate the transmembrane pore. LivH is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.	4.81174e-71
NZ_CP021983.1|WP_080807034.1|3281093_3283298_-|nitrate-reductase	gnl|CDD|239155	cd02754, MopB_Nitrate-R-NapA-like, Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol oxidation via a membrane-anchored tetraheme cytochrome. Members of the MopB_Nitrate-R-NapA CD belong to the molybdopterin_binding (MopB) superfamily of proteins.	0
NZ_CP021983.1|WP_080810194.1|3263391_3264171_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213186	cd03219, ABC_Mj1267_LivG_branched, ATP-binding cassette component of branched chain amino acids transport system. The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).	1.21004e-109
NZ_CP021983.1|WP_088430263.1|3287250_3288354_+|HEAT-repeat-domain-containing-protein	gnl|CDD|224331	COG1413, COG1413, FOG: HEAT repeat [Energy production and conversion].	1.40598e-16
NZ_CP021983.1|WP_080810199.1|3260830_3261295_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	8.02477e-23
NZ_CP021983.1|WP_080810192.1|3264167_3264869_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213191	cd03224, ABC_TM1139_LivF_branched, ATP-binding cassette domain of branched-chain amino acid transporter. LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.	4.80173e-115
NZ_CP021983.1|WP_080807035.1|3283482_3285018_-|MFS-transporter	gnl|CDD|273322	TIGR00886, Nitrate/nitrite_transporter_NarK, nitrite extrusion protein (nitrite facilitator). [Transport and binding proteins, Anions].	1.74022e-55
NZ_CP021983.1|WP_080807030.1|3278507_3278930_-|hypothetical-protein	gnl|CDD|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.08032e-13
NZ_CP021983.1|WP_080807023.1|3273826_3274903_-|hypothetical-protein	gnl|CDD|380126	pfam18154, pPIWI_RE_REase, REase associating with pPIWI_RE. Restriction endonuclease (REase) domain family, found in a conserved three-gene island that also contains a DinG-type helicase and the pPIWI_RE module. This three gene island is predicted to form a conflict system which targets R-loop formation of invasive plasmids during plasmid replication.	1.011e-10
NZ_CP021983.1|WP_088431699.1|3280522_3280987_-|nitrate-reductase-associated-protein	gnl|CDD|378232	pfam09655, Nitr_red_assoc, Conserved nitrate reductase-associated protein (Nitr_red_assoc). Proteins in this entry are found in the Cyanobacteria, and are mostly encoded near nitrate reductase and molybdopterin biosynthesis genes. Molybdopterin guanine dinucleotide is a cofactor for nitrate reductase. These proteins are sometimes annotated as nitrate reductase-associated proteins, though their function is unknown.	1.65407e-87

Protein sequences

>NZ_CP021983.1|WP_080807023.1|3273826_3274903_-|hypothetical-protein
MAVEHAEIGFAYLLKAIALSPDGRASSGLPLRETEHALDHFAVAAFKQGVHPPGNWSELVREVINEPYCEWPSYLQGDLLEPTDRLIQFGKIPDQTIKVSAWVSELADDEDYVALRNSPDEIEENQFFNEMRSYCQSQEDPQRLYVELRRYLVSSVSKTEDEMIDFLSGKPKELRGLIDKAYYIADTAPSDFACKQCGAPSIDCKPHPQCRDCISMQSIEVRKYESGEKVLRGRIASAFYFRSAIDVNLFEEFKRTLSTCELWPNLDLDGDVSVKFPNGDYWIFDCKDYLYPRSLIRKVSKERFTRDCDRFIYVIPDRVGEVYLQQARDALPNHNFLFFNRAIASVKDKVRRIRSART
>NZ_CP021983.1|WP_080807021.1|3273297_3273840_-|hypothetical-protein
MPGRDLSKLESVIEVFADEEVIESPRLTAKLEACLWAFHHLYPNEPIDLLRFVVSGNVHQIDATKPTQLHRSLQVIGGPFLTWEYARRSVLSPYFELPERVRGFSIKDDSVHLQLGECQIEQNSQAILPGRFDIYKDCMSKPIPLKETHVKRRGNGIYLLRSYKHDDGQLERIEIEGFPL
>NZ_CP021983.1|WP_080807020.1|3270652_3273301_-|hypothetical-protein
MNLIQIPPQRSANPELSVTFDQLINFTGELVSQQRLPKYYLEELHNLKLSQFPKMGETETLTFNQVVALHGPAGTGKSILIRLVTLYFANKSSYRIAIISPTITTALSTAQKLWPYLSHGKQDIAVIVGRSNRNRYRKDFLETPESSNLEHIGHDVLDYSCALAGLSEHVDRENPPCLDLKYRSERGEPNCHCPFIDNCSRHRQEQNLAQSSVLITTPEGALLSNIQLANQPMPVLEYITKTFNICFIDEADSAQQRIQSRLSPDKDLREWLEEVSSYQDVIRRKRSRNLKRLSVAGLNNDLNQASTIFDWLIGYLSRRPEACTSLEKMSFFNATFLQLNWIKKTHEFIKEIQSGWSNEDYQAIKEQLFPLLKKGVKSTSDDPFSIATSQIFYEEDFDGSPNNIIAVKLSQALSQYKSFQSLEEAEQRLFVDYFLIILAVNALLVLLHDADRGLTASEMAISIKRDAPQPALSSNPKYLENIFPRLITGRAAGLVLDRGINHDDLNLLYFSLLFSGPDLVANLSKLYELDDYAGCHFVLATATGWLPDGRSIYHLRTDGYLLQRQDRQHGQISLHYHPFYKSDGNPIFVSGLETEDKLAAISEITKRLFEGGSASIVEQDLQQYPEARRRALLTTNSKTQCWAVWEALEFLGQGDRCKVLVGDNDNLDSFDPRKRAACLRRRHAERFATIPGVDVLIAYFQGVSRDINIVPPGSREAAFCALYSLVRPHAHPTDLQISIELFLVSLFETDQRLPDILARRAKLLAEKDPPQRFNLLDQCRYYARIADRLIDQAFKRQIRYLPQASKSFMNNILLNRWWVEDIGQLWPRIMRGQVDATVRLCDAAYSSYLGDAIDRAKQLQKDPKAVFLWSQGIQALLNVKGF
>NZ_CP021983.1|WP_080810188.1|3268259_3270650_-|DUF3893-domain-containing-protein
MKISLKAAALQLNPNQLRDSYYSLTFPADLKQILLVDYSRDRSQRGNHPISLPGYQFKALVNASIPQVVCADGRLPTDKPFLFCLEHVPEERVKRLLKHWVRETFTLPKKRGQKSAVEQDITASLAAIEQASFRWQEHQLSPEDWELSVNSTAQPRDSCLFEIIPSIVVSQIVKSNLSFPEFSSQFQSIKFLPALEIASSLFQKPQFCITDVFYSKKGNPYSFMIHPRLLQIPGQPQIYLPLDFGVRRYLSKPYTRKKLPESFSVMIYTPNGVCTAKINEVRCWENNLAELLSKFDYDSVPSADELLSNPLGWSNPDLKLRFLVVNREGREKFQDVTAGVTPNDLAHLFDTIAPILQPGFEYFEPKIIDKGNSKFSKLRPSSCPDLIHYVDFQDIGKALEHEAKKLKFNLIKETDPGLVEMCNPIPVTPEDNWQQRNQDRDQVIAERVKALPERCNETKVLILPIYPENYFKQRPQEDPYNSLEEFLPDRNLLIKRLTVPTGEDEVEEISHKCKATLLTMKCRLGYHDGLIPEALKAYELPLDLQTIGIHLHKLSNGNYLPVAVKLDAKGILTGRTAISTWQPLREFIPYVQAATTIEGCKGLKLKNLTSSFFRELADSTISTLILPYSNNTRQALNGLYDSKFGADGTISLLNQNGELELFKLPNNCRVIRCRDGGELPQATLWNNDKNQPARGRAIAQFGDNSYLLIRPKASTDQSNSQESMLRPYEHRSGKVIQPKTKTTAKKITLVEANPLLQPNDKTLHWLGYLQYLQRIAPQYDNFLHLPLVLHIPSAFL
>NZ_CP021983.1|WP_080810190.1|3267204_3267639_-|hypothetical-protein
MATNETEKVRQLQRSLYRKAKQEPQTKFYSLYDKLCREDVLWEAWRQVRLNQGAPGIDGVSIREIEENGQAVTLIQQLQAQLRKQTYHFDAVRRVDIPKPQGGTRPLGIATVKDRIVQTAMKLVLEPIGSPGIIMQQQEKNASR
>NZ_CP021983.1|WP_080810192.1|3264167_3264869_+|ABC-transporter-ATP-binding-protein
MSLVLNNVHSGYGGVDILKGVNLRVAPGEIVVIIGPNGAGKSTVLKSLFGLATVRQGKIFFQGQEITRLRCDRMVRRGICYVPQTNNVFASLSVQENLEMGAFVRDDDYRPQLEQVYELFPPLRKKHQQPAGTLSGGQRQMVAMGRALMVQPQLLLLDEPTAGLSPLFVQQIFDIIGTINQLGVSLLIVEQNAKQALQMADRGYVLTMGQNRYEDTGQNLLNNPQIADMFLGG
>NZ_CP021983.1|WP_080810194.1|3263391_3264171_+|ABC-transporter-ATP-binding-protein
MLHLEGVSKTFAGFRAVDNCSFQIEAGKITGLIGPNGAGKTTLFNMVAGVLKPSQGHIVLDGRNVTGMAPHQLFRLGLVRTFQIPREFGRMTVLENLMVVPPCQLGENLWMSWFRWQRVLRQERQIRHKAEEVLGWVNLLHVRDELAQNLSGGQKKLLELGRTLMIEPKVILLDEPGAGVNRTLLRQLTDIIVRLNQEWGCTICLIDHDLELVDHLCHHVVVMAQGTVMAAGTMAEMRQNPQVQDAYLGNVHPARTLSS
>NZ_CP021983.1|WP_080810198.1|3261435_3262659_-|amino-acid-ABC-transporter-substrate-binding-protein
MTVLVAACGGTQQTTEDTEATTESASRETVDLGALLPMTGDLQAFGETSLNGINMAVDDINADGGVLGKTLAVNVGDTQTAAQPSIDAAQKLISLEGVVAIIGALSSGNTIPVAESITSKNTIPQISSASTSPVITGLNDNDFLFRTVPSDAFQGVALAQIAREQELEQLAVIYINNDYGQGLAESFKAAFEAQGGTITGMVPYEQAQASYRGELQQLAQGDATALTLIGYPENGITILKQALEEGFFDSFVFTDGMKAPEVIDAIGAETLEGAFGTAPQALTDSDAYQTFVSAYEAAYGELPPKPYIDTAYDATMLLALAIQKAGNTDGAAIRDALREVANAPGTKVGPGDWAVAVDALADGEDIDYEGASGALEFDDNGDVGGTFAHWVIQDGEIVTVEVFEPKS
>NZ_CP021983.1|WP_080810199.1|3260830_3261295_+|pentapeptide-repeat-containing-protein
MDGHQLLTQYDKGNRAFLSANLRDADLKQAYLIGINLSRSDLRRADLRGADLSRANLSHANLADANLQDANLYGANLTGSNLSRANIRHANLSKTNLQGAQLTDAELSGANFHEANLAGAHMHGVDLTGIDMVSDNPDYLRVCRARLTTGIPRS
>NZ_CP021983.1|WP_088431697.1|3259499_3260456_+|branched-chain-amino-acid-ABC-transporter-permease
MLAFGIFFATLASIYAILTLGLNIQWGYAGMLNIGVGAFFAVGAYTSAIATTPQSDNYIGGFELPMVVGLLLAMAVAGILAGLIGIITLGLRSDYLAIATIGIAEIVRLVLKNEAWLTNGVRGIAGIANPFTGLLPGANGLLYLAGVLVILGLVFWASDRAYRSPWGRVLRALREDEPASQAAGKNVLVFRLQAFILGAMFMGLAGALYAHFVAFISPEAFQPEFATFIVWVMLIAGGSGNTRGAVLGAIAIWALWSGTELITNLVPVAWVTRASALRLLLIGGLLQVILLARPEGIWPEHPPQPIDSEPKRRWRLRR
>NZ_CP021983.1|WP_088430259.1|3276187_3276532_-|hypothetical-protein
MTCLALDTWVDKLFCQVRLIQNKCDCPASKWSEALFELLDWMVDAETYFNGSVGTLCRWFGEVLNYFENGTTNGIVEGINNRLKLIKRLGFGFSNFDNFELRCLICWNIDMNLA
>NZ_CP021983.1|WP_080807029.1|3277938_3278334_-|hypothetical-protein
MLEHILEVSIDLSGNYRSFVNKYLPNADIVADRFHIMKLVNDELNRTRNQLKREANAAPDTPENKVVRQALKQSKYALLKPEDNLTEVQQNKLNEIRDASPKLAEMHGLKEQFRTIFETASKCRAIACKSA
>NZ_CP021983.1|WP_080807030.1|3278507_3278930_-|hypothetical-protein
MQPLLTKLLNLPGVEVEDYYDLGDQLILDVEAQTDRATCPRCHQDSHHVHQNHPYLVRDLSISDRTVLLRVNRRQFKCLTFGKPFSEPLNFVGKRRKHTDRFCKAMVQQLIHSDAHNVAMNNGLTDEEVASIVKYIAKKT
>NZ_CP021983.1|WP_088430261.1|3279666_3280242_-|TetR/AcrR-family-transcriptional-regulator
MARTQSSRSSARDRILATAADLFYREGVQNVGIDRIIAESGVAKMSLYNHFKSKDALIAAWLLQQDEAWRSWFQTRVEQSATEPLDRLLAMFDVLEEWFNQPDFRGCAFLNSTVELVDPNHPGYQVSMQHQQLTFDYILGLVQAANLSDPEGITRQVMIIMEGTVVIAMLQHCSGIACCGKQILSTLLEHQ
>NZ_CP021983.1|WP_088431699.1|3280522_3280987_-|nitrate-reductase-associated-protein
MSEKPVFFAFEADFVESLRCIPMQVRFKLDTCGIKLKLDQWHRFDAQERYSLAQWPCSTEAEIQTYRTYLQQLVLQHTQTPAKDLAVDPEPPWHQPGAVPVQTQEQAQALGITIPVDKWANLTPLQRFALYKLSRPGHENRNFLPALQEFKLAE
>NZ_CP021983.1|WP_080807034.1|3281093_3283298_-|nitrate-reductase
MTDATKTLCPYCGVGCGLEVLPPARRGRPVQRDSQGFPLWQTRGDRNHPSSKGQVCVKGATVGEALNKDRLKHPMLRSSLEQPFQQVSWDEALTVLTDKIQTVRQQLGPEALCMYGSGQFQTEDYYIAQKLMKGCLGSNNFDANSRLCMASAVAGYLQSFGSDGPPCCYADLELTDCAFIIGSNTAECHPIVFNRLRKHHKKNRQVKLVVVDPRRTETAKDADLHLAIKPGSDITLLNGMAHLLLRWCKLDALFIEECTHGFTDYAAVVEQYPPEKVAQACGITVPELETATRYWAEAERVLSLWSMGLNQSAEGTAKVRTLINLHLMTGQVGKPGAGPFSLTGQPNAMGGREAGGLAHLLPGYRSVANPEHRQVLEQAWQLPAGSIAAAPGLDTWEMVRALERNQVGLLWVAATNPAVSLPDLERAQAALRRSPFTVYQDAYYPTETAAYAHLLLPAAQWGEKTGVMTNSERVVTLCPAFCPPAAEARPDWEIFAEVGRRLGFTEQFAFQSAAEVFTEFVQLTRGRVCDMTGLSHECLAPGPKQWPYPADDPSQAMDKRLYTDLRFPTPDGRARFASFHSRGLAEPPSPEFPFVLTTGRLYGHWHTQTRTGRIEKTRTMYAEPLLEMNPRDAQELRLQSGQWVEVRSRRGQVRVKLRVTQTIRRGTVFLPMHWGVLWATAAECNALTHPEVCPVSLEPELKACAVHITPVSDTVTAPMQQAHPEAMPVGASPL
>NZ_CP021983.1|WP_080807035.1|3283482_3285018_-|MFS-transporter
MLAEMWSLRGRYKILHMTWFAFFLSFVVWFNLAPLATAIQEEFGLDAGQIRTIAICNVALTVPARIIIGMLLDKYGPRLTYSLLLIYAAIPCIAFAAAQNFSQLVAARLALSIVGAGFVIGIRMVAEWFPPREIGLAEGIYGGWGNFGSAASAFTMVGLATFLSFFPGAFQVADGPLLNWRMAIAATGIIAALYGILYYFSVEDTPPGKPYQRPHSTRGVEVTSQRDFWFLMAMNLPLVGILAVLAWRLKGIGFLNDGTFAITLIVLAGLYLYQAYNCWHVNQELLTGRKRYAPEDRYPFSQVALLELTYIVNFGSELAVVSMLPAFFELTFGLSKQAAGMIAATYAFMNLMSRPGGGLISDRMGSRKMTMSVLLLCMGIGYLMMSTVTNAWLLPLAIALTMVCSFFVQAAEGSTFAMVPLVKRRITGQVAGNVGAYGNVGAVAYLTIYSLLPEGVIGDRIFFQVLGVAGVVVAMLCFFFMKEPRGSFAEFHEGEEAYVTPSTPAPLPVKE
>NZ_CP021983.1|WP_080807037.1|3285166_3286753_-|ferredoxin--nitrite-reductase
MVSASKKTGTKLNKFERYKAEKDGLAVKDELEEMAQMGWEAVDETDLTQRLKWLGIFFRPVTPGKFMLRLRMPNGVLNSHRLRVLATIVQRYGDDGSADITTRQNLQLRGVRLEDIPDIFQRLKHAGMTSVQSGMDNVRNITGSPVAGLDANELIDTQGLIRKVQDMITGNGDGNYAFTNLPRKFNIAIEGGRDNSVHAEINDIAFVPAYREEQLGFNVLVGGFFSARRCAAAIPLDAWVPPDDTVVDVCRAILEVYRDHGPRANRQKSRLMWLIDDWGLDRFRSTVEAAMGRPLARAAATDEIDWDKRDHIGVHPQKQPGLNYVGLHVPVGRLQADDMVEIARLAEVYGNGEIRLTVEQNLILPNIPDSRLPVFLQEPVLQKFSLEPTPLVRSLVSCTGSRFCNFALIETKQRALALAQSLDQALAVPQPVRIHWTGCPNSCGQPQVADIGLMGTKVRKDGQAVEGVDIYMGGKVGKDAQLGQCVQKGVACEDLPQVMQQLLIDHFQAQPREADNQSQHNGHTVTAL
>NZ_CP021983.1|WP_088430263.1|3287250_3288354_+|HEAT-repeat-domain-containing-protein
MFSDQPAAIATAIDTLLAGDFQDRWQVAKQFSEIGVAALPALLELMQDEALDWEVRWFVTRILGNFESSTAIEALIQLLLHSDDDDLRQMAAAALAQIGVAAVTALAPLLQYPVQRPLVVQALARIPHRAVIPLLMQVVRDEQASVRATAMAALGHFSQPDLLPVLMMALDDREATVRAEAVRGLGRWSATQMQPAHIARLAQGLTDVDDNVAQLTANTLGRLGTPPAITALITALQGPPPPVHRQVALVRSLMRCLTEGGLSCLMERWTTLALPAQAEIISGLNHLEDRALQEQAAMTLCHYLRVGIVPAPLWPHLILTLGYLRHPDALPLLQQLLQDDDPRVRMHASEALRQLNSQGSSSAPEAP
>NZ_CP021983.1|WP_088431701.1|3288461_3289373_+|LysR-family-transcriptional-regulator
MRLEHLQAFLSVAATGSFQKAAQECNVTQSTISRQIQTLEAELGTSLFHRTSQAKLTIAGDCLLPQARKISQAWAQAVQEIDTLMAGKQPELCVAAIQSVCAYFLPPILQQFCQVYPEVQLRVTALGSDRSLKVLRDGLVDVAIVMENPLLTTGPEMVVDVLYEEPIQVLMAAEHPLSRCSAVPWAELVHRPQVMFKDGYGMQRLVKEQFQRYGVEPKTVLELNTLEAFRGIVRQGQLIALLPQSALIDSQQDETLAIRPTEDPPLVRRVLLVTTQDRVDIPPIQRFCALVRGANQRIISAVA

Crispr_ID: NZ_CP021983_25

• CRISPR_ID: NZ_CP021983_25
• CRISPR_location: 4121034-4121145
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP021983_25

Consensus_repeat	Method
CTGGTATGGCACCTCACCCACTGAGTTGCGCCAGCACT	CRISPRCasFinder

spacers of NZ_CP021983_25

>25.1|4121072|36|NZ_CP021983|CRISPRCasFinder
ATTTAAAGGCAGAAGGCAGAAGGCAGAAGGATGAAA

CRISPR arrays and Neighbor proteins around NZ_CP021983_25

CRISPR arrays

The CRISPR arrays of NZ_CP021983_25

>merge|NZ_CP021983|25|4121034-4121145|CRISPRCasFinder
CTGGTATGGCACCTCACCCACTGAGTTGCGCCAGCACTATTTAAAGGCAGAAGGCAGAAGGCAGAAGGATGAAACTGGTATGGCACCTCACCCACTGAGTTGCGCCAGCACT

>NZ_CP021983|25|26|4121034-4121145|CRISPRCasFinder
CTGGTATGGCACCTCACCCACTGAGTTGCGCCAGCACT	ATTTAAAGGCAGAAGGCAGAAGGCAGAAGGATGAAA
CTGGTATGGCACCTCACCCACTGAGTTGCGCCAGCACT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_088431773.1|4127805_4128489_-|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|238923
NZ_CP021983.1|WP_080805791.1|4109579_4110308_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293795
NZ_CP021983.1|WP_080808206.1|4128858_4130844_-|molecular-chaperone-HtpG	unknown	unknown	gnl|CDD|235366
NZ_CP021983.1|WP_080808184.1|4119162_4119600_+|DUF4079-domain-containing-protein	unknown	unknown	gnl|CDD|372553
NZ_CP021983.1|WP_088430673.1|4111599_4112553_-|sulfotransferase-domain-containing-protein	unknown	unknown	gnl|CDD|366246
NZ_CP021983.1|WP_080808188.1|4120125_4120920_+|cobalt-ABC-transporter	unknown	unknown	gnl|CDD|224058
NZ_CP021983.1|WP_080808209.1|4131595_4132639_-|hypothetical-protein	unknown	unknown	gnl|CDD|340849
NZ_CP021983.1|WP_088430679.1|4123335_4123872_+|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl|CDD|223854
NZ_CP021983.1|WP_080805786.1|4112598_4112889_-|DUF1330-domain-containing-protein	unknown	unknown	gnl|CDD|377765
NZ_CP021983.1|WP_080808212.1|4132637_4132829_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080808191.1|4121358_4122024_+|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|224331
NZ_CP021983.1|WP_080808437.1|4124601_4126242_-|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	unknown	unknown	gnl|CDD|236467
NZ_CP021983.1|WP_080808215.1|4134050_4136732_-|ATP-dependent-chaperone-ClpB	unknown	unknown	gnl|CDD|274529
NZ_CP021983.1|WP_088430675.1|4113276_4114164_-|N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP021983.1|WP_080808194.1|4122541_4123015_-|transcriptional-repressor	unknown	unknown	gnl|CDD|223806
NZ_CP021983.1|WP_080808185.1|4119787_4120180_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080808439.1|4132829_4133834_-|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|132997
NZ_CP021983.1|WP_088431771.1|4115037_4118955_+|hypothetical-protein	unknown	unknown	gnl|CDD|238121
NZ_CP021983.1|WP_088430677.1|4114169_4114655_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080805789.1|4110968_4111394_-|GFA-family-protein	unknown	unknown	gnl|CDD|226314

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_088431773.1|4127805_4128489_-|EAL-domain-containing-protein	gnl|CDD|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	2.27079e-63
NZ_CP021983.1|WP_080805791.1|4109579_4110308_-|MBL-fold-metallo-hydrolase	gnl|CDD|293795	cd07709, flavodiiron_proteins_MBL-fold, catalytic domain of flavodiiron proteins (FDPs) and related proteins; MBL-fold metallo-hydrolase domain. FDPs catalyze the reduction of oxygen and/or nitric oxide to water or nitrous oxide respectively. In addition to this N-terminal catalytic domain they contain a C-terminal flavin mononucleotide-binding flavodoxin-like domain. Although some FDPs are able to reduce NO or O2 with similar catalytic efficiencies others are selective for either NO or O2, such as Escherichia coli flavorubredoxin which is selective toward NO and G. intestinalis FDP which is selective toward O2. These enzymes belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. Some members of this subgroup are single domain.	1.50155e-50
NZ_CP021983.1|WP_080808206.1|4128858_4130844_-|molecular-chaperone-HtpG	gnl|CDD|235366	PRK05218, PRK05218, heat shock protein 90; Provisional.	0
NZ_CP021983.1|WP_080808188.1|4120125_4120920_+|cobalt-ABC-transporter	gnl|CDD|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	9.60706e-71
NZ_CP021983.1|WP_088430673.1|4111599_4112553_-|sulfotransferase-domain-containing-protein	gnl|CDD|366246	pfam00685, Sulfotransfer_1, Sulfotransferase domain.	8.77463e-49
NZ_CP021983.1|WP_080808439.1|4132829_4133834_-|glycosyltransferase-family-2-protein	gnl|CDD|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	8.80025e-25
NZ_CP021983.1|WP_080808209.1|4131595_4132639_-|hypothetical-protein	gnl|CDD|340849	cd03822, GT4_mannosyltransferase-like, mannosyltransferases of glycosyltransferase family 4 and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. ORF704 in E. coli has been shown to be involved in the biosynthesis of O-specific mannose homopolysaccharides.	8.74177e-22
NZ_CP021983.1|WP_088430679.1|4123335_4123872_+|DNA-starvation/stationary-phase-protection-protein	gnl|CDD|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	6.04736e-34
NZ_CP021983.1|WP_080805786.1|4112598_4112889_-|DUF1330-domain-containing-protein	gnl|CDD|377765	pfam07045, DUF1330, Domain of unknown function (DUF1330). This family consists of several hypothetical bacterial proteins of around 90 residues in length. The function of this family is unknown.	2.07478e-34
NZ_CP021983.1|WP_080808191.1|4121358_4122024_+|HEAT-repeat-domain-containing-protein	gnl|CDD|224331	COG1413, COG1413, FOG: HEAT repeat [Energy production and conversion].	7.58074e-34
NZ_CP021983.1|WP_080808437.1|4124601_4126242_-|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	gnl|CDD|236467	PRK09328, PRK09328, N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional.	5.12849e-85
NZ_CP021983.1|WP_080808215.1|4134050_4136732_-|ATP-dependent-chaperone-ClpB	gnl|CDD|274529	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB. Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization].	0
NZ_CP021983.1|WP_088430675.1|4113276_4114164_-|N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.76302e-09
NZ_CP021983.1|WP_080808194.1|4122541_4123015_-|transcriptional-repressor	gnl|CDD|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	2.70942e-36
NZ_CP021983.1|WP_080808184.1|4119162_4119600_+|DUF4079-domain-containing-protein	gnl|CDD|372553	pfam13301, DUF4079, Protein of unknown function (DUF4079). This is an uncharacterized family of proteins.	2.99635e-30
NZ_CP021983.1|WP_088431771.1|4115037_4118955_+|hypothetical-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	7.59014e-83
NZ_CP021983.1|WP_080805789.1|4110968_4111394_-|GFA-family-protein	gnl|CDD|226314	COG3791, COG3791, Uncharacterized conserved protein [Function unknown].	2.20588e-35

Protein sequences

>NZ_CP021983.1|WP_080808188.1|4120125_4120920_+|cobalt-ABC-transporter
MGGWLDRLDSLEFGGIILSVVLQLEQVTLDSPLSAQPLLNQISFSLAPGEFVGIVGPSGAGKTSLLRLINRLQDASHGQIQVQHRPVSAWPVVSLRQQMALVLQEPKLLGMTVQEAMHYPLKLRGMAATEARKRVNHWLERLQIPRDWQGRTELELSVGQRQRVAIARALVTEPPLLLLDEPTSALDVGHGERLLACLQELATAQGMAILMANHQLDWVEQFCSRVLYLQQGKLGGDWPATVVNWHHLREAIADVERRAAAEWD
>NZ_CP021983.1|WP_080808185.1|4119787_4120180_+|hypothetical-protein
MWLYGALSERVVLDDVGLRVTYPIWIRWLLRRGWSLDWSQITALKPRTTGQSGLVYYCLSRDQQAYLLPMRVAGFARLVQQLESHTGIDTGDVKPLAQPWMYLILLGFTGLLLWVDGWIVWTAWSLEGLS
>NZ_CP021983.1|WP_080808184.1|4119162_4119600_+|DUF4079-domain-containing-protein
MDLPSFIWLWRIAAWSMGLSVTAYLVLATLGGWLALTRLTNRPRPGWVRSLHIAVGVILVSLVLLLLSIGIIGTLGEYGSLGHSYHLPAGLTVVTLVLLSAWSAARIDVSRPWARRLHVGINGILFVALATVTFTGWQVVQKYLP
>NZ_CP021983.1|WP_088431771.1|4115037_4118955_+|hypothetical-protein
MTAKKSRRRGVVLSLQGQHKLEAARRQLEQTVNGGDRFTLEELCDRTRLALSTIARVLDAQVGVDKQTLSQVFAAFDLLLERTDYQHPGLSQAPDAFPPSGSTAIAPSPEPSPQTIDWGEAIDVSLFYGRTAELATLERWIQQDRCRLIAILGMGGIGKTALSVKLAQQSVVSREGQEGGEDQLTTSPLSPNPSGQATPTPLHPPTPSPTHSFTHIIWRTLRNAPPLELLLTDLIQVLSGQQETAASLTVGPLLSRFMHYLRQHRCLLILDNYETVLQGGQFAGAYRQGYEGYGELLRQVGELPHPSCLVLTSREKPETIADLEGETLPVRSLGLPGLLPADTDHLFDAIGLSQSPAGRRRLMEIYSGNPLALKIVATSIRELFDSDVDAFLGEETLVFNGIRRLLNQQMQRLTRLEKQVMFWLAINREWVTIAELQADIVPPVPKQRLLETLESLARRSLIEQKNARFTQQPVVMEYMTEQVIEQVGDALETLTLDLDAVSSEGLIFNAYALIKATAKEYVRDSQTRLILQPIARHLAECFSSVAALEQQMLRILTRVRRSETRGSSYGAGNLINLMSHLHLDLSDYDFSNLTIRQACLQKTPLHRVNLKDAHLIACRFAEPVPHPNSLAISPDGDRMAIGGEDGAIQMWQVSTGTPLLTLQAHSTFVFALAFAPQRDANSPNGNLLASGSMDSGIKFWEVESGQCLQAWQFERPWALAFTSDGRFLAGSLGDSDRAIHLWDWRTGQSLKTFLGHTGPASGLAFIPATASHSQRLVSGGQDCLLKIWDVDSGECLRTLTDHRGMVWSVAVHPEGDRFATASFDQTIKIWDVETEVCLQTLLGHTAEVTSVRFSPDGLLLVSSSSDRTLRLWEVATGKCLTVLQSHEDSVWAAAFIAGHTPTGEWASGQAIVSVGMDQSVRFWDISHVPPTSENSTLDLSGLSGQCLKTIQGDSTGIRSVACHPQGDLIASGGLGGVVRLWDTAGTCLRELPGHTASIWKVSFHPKGHLLASASLNGEVRVWDVATGRCRHSLWRNQSWIQAFGFSPQGHLVSASSTDATILFWDAETGECWRSIALSTDAYILGLDFHPQGHYFVSAGNNSQLRWWDMATGECFRVQSAKEGHTWAIAFHPQGHLFASVGHNLDVKLWDADSGECLDSLLGHTGIHGAVAFSPDGTILASGRSDRTIRLWDVATRQCLHVLEGHTSTVTSIAFMPSTAQPLHNQPALLVSGSLDGTVCLWDVGTGTCLKQFRPDRLYEGMMIIGTTGLTVGEKSALLALGAVEGIHPSTTRSIKPIGEAIAECH
>NZ_CP021983.1|WP_088430677.1|4114169_4114655_-|hypothetical-protein
MLHHISVAVNNPRHVATVMAEIMQGQVAPFPFNPGSFVAMAGDELGTMIEFYPLGSELIPDAHEGQAGFRLVPQPTRYVSFHAAISVPISLEEIERIADRAGWRVFPCSRDGLFDVIELWVENWLMIELLTPAIAPKYLAAFSPANIAELVNQLSLVDARR
>NZ_CP021983.1|WP_088430675.1|4113276_4114164_-|N-acetyltransferase
MQTLIPSPDLTLTIRPGTAADADACGEICYEAFKAISTQHNFPPDFPTPAVAHGLISMLFSQPDLYYSVVAEVGGRIVGSNFLQEGCAIAGVGPITVASDIQNASVGRHLMATVLDRAQQQGFAGVRLLQATFHNRSLSLYTKLGFDVQEPLANIQGPPLNLQIPGYPVRPATEADLPGCDRLCQEVHGFTRSHELLATIRQGSATVVEHDSRITGYATLIGFFGHAVGETNEDLKALIGAAPAFEGSGFMLPSRNSHLFRWCLEHGLRVVQPMTLMSLGLYNQPKGVFLPSILF
>NZ_CP021983.1|WP_080805786.1|4112598_4112889_-|DUF1330-domain-containing-protein
MSAYCVFDLLNVTDPEKMEQYRAGVFDNVARHGGKYLTVGGNPAVAEGHWQPNFLVVIEFPSLQQAHDWYDSDDYADLKALSLSGSESNAVFVEGF
>NZ_CP021983.1|WP_088430673.1|4111599_4112553_-|sulfotransferase-domain-containing-protein
MTQATLQQSLEIGDRYHYQTPIQWPQKTRELHSHHFDSTIWNEFQFRDDDIIIGSYAKSGTTWTQQIVGQLIFNGAPDVEVAVLSPWLDLRIPPKAIKLPEVEAQTHRRFLKTHLPVDALVFSPKAKYLYVARDGRDVVWSLYNHHANGNEAFYDALNNTPGRVGPALEKPSESVVQYFRDWLDNDGYPFWPFWENIKTWWAIRHLPNVMLLHYADLKRDMPGQIREIAAFLDIPIDENQWPTILEHCSFDYMKRHAEKSAPLGGTFWEGGAQTFVHKGTNGRWKDMLSTEDSQRYEAIALDQLGVDCARWLVNGMA
>NZ_CP021983.1|WP_080805789.1|4110968_4111394_-|GFA-family-protein
MTLGGSCLCKAVSYEITGPLGPTGHCHCSICRKAHGAAFVTWTLINSEQFRWTSGLELVQGYESSPGRQRCFCRQCGSHLVSTEAGNVTEVVLATIDGDPGVRPEEHIFVDSKAPWYEITDGLPQSAAWPPGMDPSLPLKV
>NZ_CP021983.1|WP_080805791.1|4109579_4110308_-|MBL-fold-metallo-hydrolase
MIVTHTTVTNTQSGTNLYEVADGIYRINTPVPGFSFNQYLIVDEEPLLFHTGLRKLFPMIHEAVAKLIPIERLRYIAFSHVEADECGSLNEWLAAAPHAIPVCGKIAAMVSIEDMADRAPHALADGEVLSVGKHSVRWFDTPHLPHAWECGYLMEEATKTLFCGDLFTQGGADLPPLIASDILGPSEVFRQQMDYYSHTKNGREMLERLASTKPRVLACMHGSAWQGDGAKLLQALAEELSE
>NZ_CP021983.1|WP_080808191.1|4121358_4122024_+|HEAT-repeat-domain-containing-protein
MSIVDLEHISQQLDSKDPKDRMLALAALRGVSPEQAAPLIRKVLYDGNLQVRSMAVFALGLKPDEQACDTLINLLEHDPDYGIRADAAGALGYLEDPRAFGPLVRAFYEDTDWLVRFSAAVSLGNLKNPQAHDVLIEALGSDQEIMQQAAIAAIGEIGDMKALDEILTFAQSEDWLVRQRLAEALGNLPSSKGESALRFLEKDAHPQVATAARLSLQRLVQ
>NZ_CP021983.1|WP_080808194.1|4122541_4123015_-|transcriptional-repressor
MTTDPSQAGDLMKELFHQGGFRFTRQRQKIIGLFHACQEGQHLNADTIHHQLACQGEHVSPSTIYRTLHVMVNLGLLRELELADGKKSYELSNPYAGDHHHLVCVQCGAVVEFEEDMTSEVAHDQAASQGYSILDCQFTIYGVCSNCQHHLIPTHLS
>NZ_CP021983.1|WP_088430679.1|4123335_4123872_+|DNA-starvation/stationary-phase-protection-protein
MPTTETLLQSSNEITDNPILLEKSITEPICEGLGVAYASFMALYLQYQKHHFVVEGAEYYMLHEYFAESYGEVQEHAHDVGERLHGLGGIPAHSFSKLAQLCCFEQESDDVFRCRLMIEHDLKAEQSLVDVLRRQAAQAESLGDRATRYLYEQILLKTEERAYHLEHFLTRDSLKLGW
>NZ_CP021983.1|WP_080808437.1|4124601_4126242_-|peptide-chain-release-factor-N(5)-glutamine-methyltransferase
MASGPGGWTDGLPGRCGGGPHLSVVLGQFDWTGGVSPGIAGGDPGPGRGIAIRGSGLVRGGSIWESFGWFRDWRNARRITGSRRIPSSGTEGRPARDYPDSPAAQSRCDAWCASRLGSVVIGGSGDRRYRCDRRSISRSLDGQPHSENWSGLVASPGPVVLLRSTAFPHPGAALLQRPAPYALELSAVSRLRHRTPPVAAGGRGLSLRTRPGATAVSARPIEPSSAGLGAVEGAVSRTEGAHTITGSELWQWWQMARQQALAQQIDPAEVDWLVRAISDVDGLSLRLQSFRQRAAIPCRYGLPALETLWQRRRQEHIPVQYLVGQTQWRDFTLQVSTAVLIPRPETELLIELVHAAVAQTPALEAGTWVDLGTGSGAIALGLAKALPRAHIIAVDCSAEALALAAANAAANGLCDRIELRQGHWFTPLADLRGQLAGMVANPPYIPSAMVATLAPEVAVHEPRLALDGGPDGLTAIQHLIDAAPDYLQANGLWLIEAMAGQPATILQQLQQHGAYCDLQRHRDLAGLERFVQARCQGPQGSRRHSQ
>NZ_CP021983.1|WP_088431773.1|4127805_4128489_-|EAL-domain-containing-protein
MAFQPIVNMATRQIFAQEALVRGLHGESAGYVLAQVTDKTRYDFDQACRVKAVELAARLNIQSDLSINFLPNAVYHPENCIQTTLMAAKRYQFPLDRIIFEFTESEEVKDLTHLRSIVEDYKRRGFRTAIDDFGAGHSGLNLLADFQTDYIKLDMALTRHIDQDNSRQAIVKGIVQVCRELCVELIAEGIETYEEMQALQDMGIELLQGFYFAKPSWQSLATVHWPA
>NZ_CP021983.1|WP_080808206.1|4128858_4130844_-|molecular-chaperone-HtpG
MTTILEQGNINIHTENIFPIIKKWLYSDHEIFLRELVSNAVDAIQKLSMVARAGDFSGDITNPEIEITLDKDKGTLSVCDTGIGMTADEIKKYINQVAFSSAEEFISKYKDNADQPIIGHFGLGFYSSFMVASRVEIDSLSYQEGATAVHWSCDGTTQFELSDSDRSQHGTTITLTLMEDEKEYLEPARIRQLIKTYCDFMPVPIKLDGEVVNQHEALWKKSPSSLSDDDYLEFYRYLYPFQEDPLLWVHLNTDYPFVVNGILYFPKLQPDIDVTKSHIKLFCNQVFVTDNCEEVIPRFLMPLRGVIDSSDIPLNVSRSFLQNDRTVRRIADYIARKVADSLKQLYRSDRKQYVRSWQDLGTFVKFGSLNDEKFKQQVEDILIFRTTANLSQAQGDSAKVEVESGGDDVWQEVSANEESATDQRGYHYTTLKEYLERNKDRHENRVFYATDEVSQATYIELHKSQGLEVLFMDSFIDTHFVSFLEREYSDIKFSRVDADLDDTLVDREQDSEIVDPTTNKTRADQIKELFEQALNKPKVNIKPQALKGDATAPPAMVLLPEATRRMQEMSALIQQKAIEFPEEHVLMVNTAHPLIQNLLNLSQGSIIQTGGGSSPSAELAQLICQQVYDLALMAQKGFDAEGMTTFVDRSNQLLTQLTEKV
>NZ_CP021983.1|WP_080808209.1|4131595_4132639_-|hypothetical-protein
MKVLAWPAFKTRYKNPYPWLLYTSMVQSGVTVEELSPRRLLTGRYDIIHIHWPVETIVRHPRWSMALLRMLLFMGLLHWARWREAQVVWTIHDEQPHVLLHPGLAHWCQSLLVHRVDATITLCQVSQQRLPAQLPELADKPSFVIPHGHYRQVYANQISKTAAKDQLGIPDSHPTLLFLGYISPYKNVPQLITTFRQIQQPDIALVVAGHPDDEPLRTAIEQAAGDDGRVRLHLRFIADDGLQVFFQAADLVVLPFQAILNSGSVLLALSFDRPVLVPHLGAMPEWQQQLGTTWVETYEGPLTAERLEAALMAQTNAERPRQAPLDWLDWSVIGDKTLDVYRQLCRS
>NZ_CP021983.1|WP_080808212.1|4132637_4132829_+|hypothetical-protein
MAMAAVAIPSQNAHIQEKCSRQPLRGHLKTRLKALQGKRFRAYGSVGQNPVWSKVAGYFPNIL
>NZ_CP021983.1|WP_080808439.1|4132829_4133834_-|glycosyltransferase-family-2-protein
MTFSEAFLDFTVVICTYNGAQRLPAVLACLQQQVTPAQLRWEILIIDNNSGDHTASLIRSYEHTCQAQCSIRYSFEPQQGASFARQRAIRLAHSELIGFLDDDNLPDPNWVAAAYDFGQQHPQAGAYGSQIYGQFEAPPPQNFARIRSFFALTQRGPTPHRYERRQRVLPPGAGLVVRKQAWLETVPARCILSGPTPTQRLAGEDLEAVSYIQLSDWEIWYNPAMTLRHAIPAERLQRHYLLPFFRGIGLSRYVTRMLSVYPWQRPLILPCYLLSDTLKVLWHLLRYRHRIDEDLVAACELQLFLWSLISPFYLGQRFICLRIFPGHPYRSGTP
>NZ_CP021983.1|WP_080808215.1|4134050_4136732_-|ATP-dependent-chaperone-ClpB
MQPTDPDKFTTKAWDAIVEAQAVARRYKHQYLEVEHVAIALLEQEAGLGHTILKKAKLEPDLLLSELETFAQRQARVRMATDNNLYLGQSLDRLLDKAEDARQSLRDKFISIEHLLLGFVEDDRIGRRLLRGFEVDAAALMTAIKLVRGNQQVTDQNPESHYQALEKFGRDLTEQAREGKLDPVIGRDEEIRRVVQVLSRRTKNNPVLIGEPGVGKTAIAEGLAQRIINGDVPESLKNRQLISLDIGGLIAGAKYRGEFEDRLRSVLREVTESSGQIVLFIDELHTVVGTGASQGTMDAGNLLKPMLARGELRCIGATTLDEYRKHIEKDAALERRFQQVYVDQPSVDDAISILRGLKERYEVHHGVHISDSALVAAATLSDRYIADRFLPDKAIDLVDEAAAKLKMEITSKPVELETIDRRLMQLEMEKLSLQAEGQSAGPASRSAQERLERIQQEIDQLAEKQQTLTGQWQSEKQTLEAINTLKEEEDQLRVQIEQAERAYDLNTAAQLKYGRLETVQREREAKEAQLLEIQARGSTLLREQVSEADIAEIVAKWTGIPVNRLLESERQKLLQLESYLHQRVIGQEEAVAAVAAAIRRARAGMKDPGRPIGSFLFMGPTGVGKTELARALAECLFDTEASLVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLSEAVRRHPYSVVLLDEVEKAHPDVFNILLQVLDDGRITDGQGRLVDFRNTVIVMTSNIGSDHILDVAGSDAQYEAMRKRVMQALRSHFRPEFLNRVDDLILFHALGRQQLRQIVAIQVQRIQRLLADQKLQIELSESALDYIAEVGYDPVYGARPLKRAIQKELENPIATKILENAFPAGSIIQAERADGSLQFHCTPPPDPSPTPEPSTQIQSPVS

Crispr_ID: NZ_CP021983_26

• CRISPR_ID: NZ_CP021983_26
• CRISPR_location: 4429520-4429615
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP021983_26

Consensus_repeat	Method
TGAACCACTAGGGGTGTCTAGTATGGTGG	CRISPRCasFinder

spacers of NZ_CP021983_26

>26.1|4429549|38|NZ_CP021983|CRISPRCasFinder
GCTTGGCGTTGAAACCTCGTTACAGGTGGCTAGGCATT

CRISPR arrays and Neighbor proteins around NZ_CP021983_26

CRISPR arrays

The CRISPR arrays of NZ_CP021983_26

>merge|NZ_CP021983|26|4429520-4429615|CRISPRCasFinder
TGAACCACTAGGGGTGTCTAGTATGGTGGGCTTGGCGTTGAAACCTCGTTACAGGTGGCTAGGCATTGAACCACTAAGGGGTGTCTAGTATGGTGG

>NZ_CP021983|26|27|4429520-4429615|CRISPRCasFinder
TGAACCACTAGGGGTGTCTAGTATGGTGG	GCTTGGCGTTGAAACCTCGTTACAGGTGGCTAGGCATT
GAACCACTAAGGGGTGTCTAGTATGGTGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_088430860.1|4438028_4438469_+|hypothetical-protein	unknown	unknown	gnl|CDD|215568
NZ_CP021983.1|WP_088431793.1|4432355_4432976_+|LysE-family-translocator	unknown	unknown	gnl|CDD|224199
NZ_CP021983.1|WP_088430844.1|4424462_4425326_-|KR-domain-containing-protein	unknown	unknown	gnl|CDD|180446
NZ_CP021983.1|WP_088430846.1|4425353_4426409_-|NAD-dependent-epimerase	unknown	unknown	gnl|CDD|187652
NZ_CP021983.1|WP_088430850.1|4427961_4429416_+|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl|CDD|224089
NZ_CP021983.1|WP_088430854.1|4430320_4430572_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_088431795.1|4432997_4434101_-|aminotransferase-class-V-fold-PLP-dependent-enzyme	unknown	unknown	gnl|CDD|223594
NZ_CP021983.1|WP_088430856.1|4431030_4431963_+|cation-transporter	unknown	unknown	gnl|CDD|224151
NZ_CP021983.1|WP_080811124.1|4438474_4439299_+|TlyA-family-RNA-methyltransferase	unknown	unknown	gnl|CDD|224110
NZ_CP021983.1|WP_080811126.1|4439896_4441207_+|ATPase	unknown	unknown	gnl|CDD|379114
NZ_CP021983.1|WP_088430848.1|4427465_4427765_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811098.1|4420947_4421181_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811113.1|4429959_4430292_-|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|143393
NZ_CP021983.1|WP_080811107.1|4426413_4427430_-|NAD(P)-dependent-alcohol-dehydrogenase	unknown	unknown	gnl|CDD|176237
NZ_CP021983.1|WP_080811103.1|4422749_4423283_-|hypothetical-protein	unknown	unknown	gnl|CDD|226158
NZ_CP021983.1|WP_088430840.1|4421279_4422062_-|hydrolase	unknown	unknown	gnl|CDD|238877
NZ_CP021983.1|WP_088430842.1|4422165_4422630_-|hypothetical-protein	unknown	unknown	gnl|CDD|226158
NZ_CP021983.1|WP_088431797.1|4434601_4436053_+|recombinase-B	unknown	unknown	gnl|CDD|274603
NZ_CP021983.1|WP_088431532.1|4423335_4424396_-|IS630-family-transposase	unknown	unknown	gnl|CDD|315923
NZ_CP021983.1|WP_088430858.1|4436165_4436981_+|acyl-[acyl-carrier-protein]--UDP-N--acetylglucosamine-O-acyltransferase	unknown	unknown	gnl|CDD|183539

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_088430860.1|4438028_4438469_+|hypothetical-protein	gnl|CDD|215568	PLN03088, PLN03088, SGT1, suppressor of G2 allele of SKP1; Provisional.	5.35776e-06
NZ_CP021983.1|WP_088431793.1|4432355_4432976_+|LysE-family-translocator	gnl|CDD|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	4.89816e-27
NZ_CP021983.1|WP_088430844.1|4424462_4425326_-|KR-domain-containing-protein	gnl|CDD|180446	PRK06180, PRK06180, short chain dehydrogenase; Provisional.	9.01608e-112
NZ_CP021983.1|WP_088430846.1|4425353_4426409_-|NAD-dependent-epimerase	gnl|CDD|187652	cd08948, 5beta-POR_like_SDR_a, progesterone 5-beta-reductase-like proteins (5beta-POR), atypical (a) SDRs. 5beta-POR catalyzes the reduction of progesterone to 5beta-pregnane-3,20-dione in Digitalis plants. This subgroup of atypical-extended SDRs, shares the structure of an extended SDR, but has a different glycine-rich nucleotide binding motif (GXXGXXG) and lacks the YXXXK active site motif of classical and extended SDRs. Tyr-179 and Lys 147 are present in the active site, but not in the usual SDR configuration. Given these differences, it has been proposed that this subfamily represents a new SDR class. Other atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.47878e-101
NZ_CP021983.1|WP_080811103.1|4422749_4423283_-|hypothetical-protein	gnl|CDD|226158	COG3631, COG3631, Ketosteroid isomerase-related protein [General function prediction only].	1.58369e-10
NZ_CP021983.1|WP_088431797.1|4434601_4436053_+|recombinase-B	gnl|CDD|274603	TIGR03491, TIGR03491, RecB family nuclease, putative, TM0106 family. Members of this uncharacterized protein family are found broadly but sporadically among bacteria. The N-terminal region is homologous to the Cas4 protein of CRISPR systems, although this protein family shows no signs of association with CRISPR repeats.	0
NZ_CP021983.1|WP_088431795.1|4432997_4434101_-|aminotransferase-class-V-fold-PLP-dependent-enzyme	gnl|CDD|223594	COG0520, csdA, Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones].	8.22315e-91
NZ_CP021983.1|WP_080811124.1|4438474_4439299_+|TlyA-family-RNA-methyltransferase	gnl|CDD|224110	COG1189, COG1189, Predicted rRNA methylase [Translation, ribosomal structure and biogenesis].	6.20039e-119
NZ_CP021983.1|WP_080811126.1|4439896_4441207_+|ATPase	gnl|CDD|379114	pfam13304, AAA_21, AAA domain, putative AbiEii toxin, Type IV TA system. Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.	1.459e-23
NZ_CP021983.1|WP_088430856.1|4431030_4431963_+|cation-transporter	gnl|CDD|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	3.46659e-75
NZ_CP021983.1|WP_080811113.1|4429959_4430292_-|nucleotidyltransferase-domain-containing-protein	gnl|CDD|143393	cd05403, NT_KNTase_like, Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins. S. aureus KNTase is a plasmid encoded enzyme which confers resistance to a wide range of aminoglycoside antibiotics which have a 4'- or 4''-hydroxyl group in the equatorial position, such as kanamycin A. This enzyme transfers a nucleoside monophosphate group from a nucleotide (ATP,GTP, or UTP) to the 4'-hydroxyl group of kanamycin A. This enzyme is a homodimer, having two NT active sites. The nucleotide and antibiotic binding sites of each active site include residues from each monomer. Included in this subgroup is Escherichia coli AadA5 which confers resistance to the antibiotic spectinomycin and is a putative aminoglycoside-3'-adenylyltransferase. It is part of the aadA5 cassette of a class 1 integron. This subgroup also includes Haemophilus influenzae HI0073 which forms a 2:2 heterotetramer with an unrelated protein HI0074. Structurally HI0074 is related to the substrate-binding domain of S. aureus KNTase. The genes encoding HI0073 and HI0074 form an operon. Little is known about the substrate specificity or function of two-component NTs. The characterized members of this subgroup may not be representive of the function of this subgroup. This subgroup belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, co-ordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are conserved in this subgroup.	4.77508e-12
NZ_CP021983.1|WP_080811107.1|4426413_4427430_-|NAD(P)-dependent-alcohol-dehydrogenase	gnl|CDD|176237	cd08276, MDR7, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family. This group is a member of the medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, but lacks the zinc-binding sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	5.6653e-161
NZ_CP021983.1|WP_088430850.1|4427961_4429416_+|PLP-dependent-aminotransferase-family-protein	gnl|CDD|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	1.63268e-135
NZ_CP021983.1|WP_088430840.1|4421279_4422062_-|hydrolase	gnl|CDD|238877	cd01839, SGNH_arylesterase_like, SGNH_hydrolase subfamily, similar to arylesterase (7-aminocephalosporanic acid-deacetylating enzyme) of A. tumefaciens. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	1.01934e-64
NZ_CP021983.1|WP_088430842.1|4422165_4422630_-|hypothetical-protein	gnl|CDD|226158	COG3631, COG3631, Ketosteroid isomerase-related protein [General function prediction only].	1.78689e-07
NZ_CP021983.1|WP_088431532.1|4423335_4424396_-|IS630-family-transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.97716e-29
NZ_CP021983.1|WP_088430858.1|4436165_4436981_+|acyl-[acyl-carrier-protein]--UDP-N--acetylglucosamine-O-acyltransferase	gnl|CDD|183539	PRK12461, PRK12461, UDP-N-acetylglucosamine acyltransferase; Provisional.	2.50674e-124

Protein sequences

>NZ_CP021983.1|WP_088430850.1|4427961_4429416_+|PLP-dependent-aminotransferase-family-protein
MRLSPLEPSQDKVLYQQVADRLQEQIANGTLKPGDRLPSIRKLKQQLSVSFSTVTEAYRLLEDRGLISARPQSGYYVKLTALQQHLEPSLTEPYARVCEIKTSLTFKLFSNLLEPDVIQLGAATPSPEHLPVAPLNRLMAKVMREHPEAHTYNVPAGCERLRTEVSKRMLDAGCSIHPDHLLITNGAHEAIYLSLQAVTTPGDTIAIASPTYFALLETLKALNLKVCALPTHPRQGISLSHLEAALASGNVQACLLVSNFSHPLGTCMEDDTKKQLVELMTRYQVPLIEDDVYGELYFEGTRPKAIKAFDTDNRVIYCSSVSKTLSPGLRLGWCSGGCYHLKVVYRKSVMNRMSAIAPQLAVTAFLANGGYDRHLRHLRRTYQTQMHRMLQAICDYFPAETCVTHPHGGHVLWLEMPEGFDAIQLYDDALQRGISIAPGPIFSASGECYRSCFALNTALPWSDRIEQAMQTLGHLAKKQMAVNF
>NZ_CP021983.1|WP_088430848.1|4427465_4427765_-|hypothetical-protein
MGQSHCCAYLDQKVSASSQSVEGQFLGRKAVLLGLKIHLARLGEAVARGFRLSKEPVISKQQDRQGDFYYRVYDPYHRSHHTFRAENEVRIWLEERHYR
>NZ_CP021983.1|WP_080811107.1|4426413_4427430_-|NAD(P)-dependent-alcohol-dehydrogenase
MKSIALTDAFGSDHLRLIATDLPDFGPDEILVKLQAAALNYVDLLLIKGDLNPDLSFPVMPVSDGAGVVEAVGSQVTEFQPGDRVVTTYIPDWIDGRYTPANSQMTTRPGMGRRPGQLAEYKSFRAHELIKRPTFLSAAEAATLPIAALTAWNALAYGQAKPGDTVLLHGTGGVSIFALQFAKAAGLRVIITSSSDHKLAKAAALGADHGINYRQTPDWVGEVLAATTGAGVDLVVETVGGQNLNRSLDALRLDGHISVVGFLEGQHSSLDLVSLNLKRAKLHGLSVGSRQDFADMLRAMAANQIHPVMDKTFPLEATPEAFRYLESGHHFGKVVIEI
>NZ_CP021983.1|WP_088430846.1|4425353_4426409_-|NAD-dependent-epimerase
MTTSMQALIAGASGIIGRGTARTLRERDIPVQGLARRPIHGMETVSVDLCDRTATVDAIAQQAAHTTHLFYAALAPHPNLSLEAQQNAQMLATLLDALEKASAPLERVVIYQGFKIYGIHLPGAVVPTPAREDDASHMPPNLYQAQAAILTERAPHADWDYVVLRPDLVVDGNGYGNPMHIALTIGVFAELSRELGIPLRYPGTNAAYQVLMQFTDADLLGRASLWAATTPAAGGEAFNVTNGDVFRWQRLWPDVAEYLGLDMAPPIPLKLTEHMADKGEVWRRLAERHGLVEPNLDKLVGWAFGDMLFNTETDIISDVNKIRRFGFTETADARLTLLKALDRLKEQRVLP
>NZ_CP021983.1|WP_088430844.1|4424462_4425326_-|KR-domain-containing-protein
MTTQQPRIWFITGSSRGLGRALTETVLELGDSVVATARKPERLTDLVQQYGDRLLALPLDVTQPFAIQTAVMHALQAFGHVDVLVNNAGYGVFGAVEEVTAPAVRQQFETNVYGALEVTCALLPHLRRQRSGHILNISSSGGFVGFPGAGIYGASKFALEGWSEALAQEVAPLGIRVTIVEPGAFRTAFNGVLRSPAQTIQDYAETSGQMMHWLRQMHGQQPGDPQKAAAAMMQVVDHPDPPLRLVLGADALIQRVAVLLIATISLSILMSQPLHPDAALNLMPSLI
>NZ_CP021983.1|WP_088431532.1|4423335_4424396_-|IS630-family-transposase
MNSFQLEHQQKVDNRAILSDFISSNPDSRELKRALAVKMALEGEPYFKITKFLGINKSFITYWKNRFEAQGIEGIKLGYQGSKSYLTPDDRTEIISWLRTRNYWNFDELVSYLDEHYDVIYKSKQSYYTLFSEAGISWKKSQKTNPKSDPALVKKKREEIQGFIRQNQFKIESGELIVLFLDECHLLWGDVCGYVWGKTDMRIEIPITNERIRQTYYGALNYQTKEFILHPYEKGNGENTVAFMKYLQEQNPGKQIALIWDGASYHKSQEIKDFLATVNHGKEETEWQFKCILFAPNSPEQNPVEDVWLQAKNSLRRFWRLCRSFPAVKYLFEFFIDHQKFDFSKIEEYSPCS
>NZ_CP021983.1|WP_080811103.1|4422749_4423283_-|hypothetical-protein
MEFFKNQRLSDTFSTELGNAPTSRNELLKNATVQQTMTRSVVSQYFKMVYADAEPELIASLFSEDVDFYIPGAVDIVPWIGRRHGRSGVVDFIQELRSYTEPIKFDIRSIVVEGHQGIALGALETLVKSTGKIIKSEFAFEFSVQGSLITRYRIFEDGFAVAKAIGESENNAQEIHF
>NZ_CP021983.1|WP_088430842.1|4422165_4422630_-|hypothetical-protein
MNPKERIRIVEAYFRKIDAKDATVFDLFTEDVQMFFPKFGFGYGKADMIQFSEIMGRHLERLEHDIENFNYIVAGDSVVVEGTERGVTRNDVRWPDGLISEGRFCNVFEFRGDLIRRVFIYVDPDYTSADQERIAIFRGNQRNPIVDVSPHSSN
>NZ_CP021983.1|WP_088430840.1|4421279_4422062_-|hydrolase
MTSPLKRAIALLIATVTTLTLTTRSVHSDSPDTPVRVLVYGDSNTWGWVPTESGFPTTRFLSEQRFPGVMQRELGPEFDIIENGLNNRTTNLDFPEAIDLVAGGGFNGARTLPGLLAAHAPLDWVVIMLGTNDLRAPFHRTATEAAAAIAPLIDIVHDSGGSVANTYDAPRVLIVAPPRIGNMPHPEMAAAFSDAERTSQGFAAAYAAVAEAAAVPFLDATEIIGVTAGWDGIHLSAEQHQRLGQTLAIALYTSTASAPD
>NZ_CP021983.1|WP_080811098.1|4420947_4421181_-|hypothetical-protein
MNFETLGEITDIEVIAVGNSIREVERLRKAYGTGRWRKLKGIATISLDDGSICRAELHWYEAHNIGKKEFKIKRFLE
>NZ_CP021983.1|WP_080811113.1|4429959_4430292_-|nucleotidyltransferase-domain-containing-protein
MKPVLPNALSPVLKPLKQYLQEHYQDRLNQVVLFGSHARQQATENSDIDILVVLDDPVDASAEGRRTSEFIAQLCLEHDLLISCLFLPTSRYQTENSPLLRNIRQEGIVL
>NZ_CP021983.1|WP_088430854.1|4430320_4430572_+|hypothetical-protein
MGVEHNHYNILVLWGDRLGGVDVLDGQDKLPDEFSLSSLDIKSAEMTNIMMSDNTCDASFRASAARDPESRSSALSPRECLNP
>NZ_CP021983.1|WP_088430856.1|4431030_4431963_+|cation-transporter
MHIHALDQWQHSHDFADDRSHAEKNTKLVMLLTAVTMVAEIVAGTFFGSMALLADGWHMATHVAAFGITIFAYHYARRHAADPQYTFGTGKVSVLGGFASAVALAVIAFLMAFESVERLFQPQMIQFNEAIGVAILGLVVNLVSAWLLQAQPDHGHHHHHHHDQNLRAAYFHVLADALTSIFAIVALLAGQFLGWVWMDALMGLVGAGVITKWAYGLVRDTSSVLLDGAVDRKIKLDIVTTIEEDADNRVTDLHVWYLNQDHLAATISLVTHYPQAPEHYKQLLSRLPSLSHVLVEVNQCHGEPCLAVRP
>NZ_CP021983.1|WP_088431793.1|4432355_4432976_+|LysE-family-translocator
MTGRHIATLFGTMLVLAVVPGPSDVAVVARSLISGFTQGLIMVVGIVMADLLFIVLAVFSLAEVADSLGALFVIVNYGCGLYLIGLGIHALRSRPHSIEVSDVRQYPGYSSFLVGLLITLADPKAILFYMGLLPAFVELSTITVLDILVIMLIATTVVGGVKGTYACLANQAKGVFKNSRLRQRLESIAGCVLLGIGLFIVLQPHV
>NZ_CP021983.1|WP_088431795.1|4432997_4434101_-|aminotransferase-class-V-fold-PLP-dependent-enzyme
MPQAALEAIQRAHWKIQQEGPFCGQINRWLQQQAEATRQLMATELGCPATAITLTEDVTVGCNIPLWGLEWQAGDHILLSDCEHPGVIAAVQEICRRFGVETSQFSLLDGLDQRSPVEAMAARLRPRTRLLVISHLTWNTGQVLPLADMVRYCHDRPQPVWVLVDAAQSVGSLPLNLTASEVDFYAFTGHKWWCGPAGLGGLYVRPALCDRIHPTFIGWRGITTDDQGQPTGWKPNGQRYEVATSDYALQAGLQAALSLHQQWGSADQRYQRICQLSHYLWQQLQTLPQIRCLRQVPPESGLVSFQILAAGQPAPSQHVSLVQTLESQGFMLRTLLFPHCVRACVHYFTTEAEIDQLVGAIKTAGSA
>NZ_CP021983.1|WP_088431797.1|4434601_4436053_+|recombinase-B
MLFHYQRCSRRAFLDLYGTSTQPDPPSDYLEKLKQDSTHHRQGMLQRYQPRHRPLYPARDWQAGRQATQALMAQGVDHITQGVLTAPATAGIALVSRPDLLIKQPGKSFWGDWYYVPMDIKLGKKPKLDYQVVAAFHAYLLSHTQGMWPEESWLALREGRLYSVDLVRQIPKMQEVLADCLQDLQAETAPSVFISHSRCDLCHWFSHCYDQAKTTQHLSLLPGVTPARYSQLQGLQLTTVEALAQANPRRLAPLPGFGETVAEKLIHQAQAILHNRAIARTDEDNRFPLVPGQLPSAAVELYFDIEAAPDQDLIYLHGVLVVNHEAGSEEFHALLAETPEEEYEAWQGFLALVQRYPEAPIYHFCPYEAQTARKLARLYGTADAVVEPLLARFVDMHWCITESVTLPIESYALKHIARWIGFDWRDSGANGAQSICWYNDWLTTCDRTYLEAILRYNEDDCRATYWIKRWLVEFAQPFWAPKP
>NZ_CP021983.1|WP_088430858.1|4436165_4436981_+|acyl-[acyl-carrier-protein]--UDP-N--acetylglucosamine-O-acyltransferase
MTIHPTAVIEAGAVLGQGVVVGPFSYVAHDTYVGDGCHLGPHVTLLPYTTLGAGSRVHAGAVLGDIPQDLSFNDAVSHVRVGQQCVLREGVTIHRGTQPDSVTVVGDGYLLMANSHVGHNARLGKRVIMANGALVGGYAEVGDRAFISGNCLIHQFTRVGRLVMMSGGSAAQKDVPPFCMTRSSTTNIIMGLNVVGLRRAAFSAPERQTLQRALRVLYRSGLNIQTATAKLEQEFDSPLVTEICQFVRGSKRGICKFVKPAAKASGDEAGW
>NZ_CP021983.1|WP_088430860.1|4438028_4438469_+|hypothetical-protein
MADIVSLEFWVWLVVIGGTLAVGMISMSRAYLRPPSKTLLFPRPQPQSSLPLSQAARLSFEQGCEAFKQQQFRRTIDRFAQVIAAEPNCAEAFHNRGLMQANLGNDNYAIADLLQASDLYDRQGTKAGLEQVKAQLQQMATRSQDK
>NZ_CP021983.1|WP_080811124.1|4438474_4439299_+|TlyA-family-RNA-methyltransferase
MAKQRLDALLVERGLCDSRQMAQRLIRAGAVRVNQQLVDKPGHAIAANADIQVKRRAPYVSRGGEKLAKALADFEISVCDRICLDGGISTGGFSDCLLQAGARLVYGIDVGYGQVAWKLRQDPRLVLRERTNLRHLTPETLYGPDRSWPDLGVMDVSFISLTKVLPAFWRLLQPPREVVLLVKPQFEVGREQVGKKGVVRDAKVQAQAIWTVWQTAQALGWHYRGLTWSAMVGPAGNIEYLLWLSADPGVSLEGPELAMIQDRTQTAQTTLLKS
>NZ_CP021983.1|WP_080811126.1|4439896_4441207_+|ATPase
MLTQIELKNFKSYRSGTLQLGRLTVLIGANASGKSNVIEALRLLARIAEGERLSLLGGPYKQDETIFRGGVENLGYRGSKSFGLSCVTTEPEWKDLSIDLSLGGDGDLHVTKEKITSHTSTVPLYEITSAPQGAGSDVFVTYNNFARGGKKPSIVCSSHMAIFTQLLSDIRFRPENTKSRKIIPKVAERYVQWLSSIVFLEPEPSSMRSYGHKVDKVLKEHGENLSGVIYNLCLNPNVKSSVLDFVQSLPEQDIENIDFIETPRDEVMLQLTETFGGASTTYDASILSDGTLRVLSIAAAMLSAPEQSLVVIEEIDNGVHPSRAADLLERISSIAKNRDLRVLISSHNPALLDALPDEAIPETVFCYRSPQDGSSQLVRLQDIPDYPELIAQGSVGHLMTRGLLERFVKQHPGTEQKKKKAMEWLASLAVVGEPRE

Crispr_ID: NZ_CP021983_27

• CRISPR_ID: NZ_CP021983_27
• CRISPR_location: 4878256-4878366
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_CP021983_27

Consensus_repeat	Method
CCCACAGCCGAAGCACCTCAAAGGTGTGACGATTCTCCG	CRISPRCasFinder

spacers of NZ_CP021983_27

>27.1|4878295|33|NZ_CP021983|CRISPRCasFinder
CATTGGGAAACCCTGGAACATCAGGCCATGCAA

CRISPR arrays and Neighbor proteins around NZ_CP021983_27

CRISPR arrays

The CRISPR arrays of NZ_CP021983_27

>merge|NZ_CP021983|27|4878256-4878366|CRISPRCasFinder
CCCACAGCCGAAGCACCTCAAAGGTGTGACGATTCTCCGCATTGGGAAACCCTGGAACATCAGGCCATGCAACCCACAGCCGAAGCACCTCAAAGGTGTGACGATTCTCCG

>NZ_CP021983|27|28|4878256-4878366|CRISPRCasFinder
CCCACAGCCGAAGCACCTCAAAGGTGTGACGATTCTCCG	CATTGGGAAACCCTGGAACATCAGGCCATGCAA
CCCACAGCCGAAGCACCTCAAAGGTGTGACGATTCTCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_088431080.1|4875293_4876040_-|DUF4058-domain-containing-protein	unknown	unknown	gnl|CDD|379094
NZ_CP021983.1|WP_088431082.1|4891823_4892399_-|hypothetical-protein	unknown	unknown	gnl|CDD|275380
NZ_CP021983.1|WP_080811279.1|4884278_4884725_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811290.1|4869744_4870215_-|thioredoxin-dependent-thiol-peroxidase	unknown	unknown	gnl|CDD|224146
NZ_CP021983.1|WP_080811275.1|4885269_4885605_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811274.1|4885749_4887213_-|hypothetical-protein	unknown	unknown	gnl|CDD|240017
NZ_CP021983.1|WP_080811280.1|4878500_4882442_-|NACHT-domain-containing-protein	unknown	unknown	gnl|CDD|227922
NZ_CP021983.1|WP_080811291.1|4869289_4869745_-|NUDIX-hydrolase	unknown	unknown	gnl|CDD|223979
NZ_CP021983.1|WP_080811289.1|4870338_4871532_+|HlyC/CorC-family-transporter	unknown	unknown	gnl|CDD|224173
NZ_CP021983.1|WP_080811269.1|4889674_4889956_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811293.1|4868467_4869217_+|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|277316
NZ_CP021983.1|WP_080811270.1|4888293_4888557_-|DUF4365-domain-containing-protein	unknown	unknown	gnl|CDD|379535
NZ_CP021983.1|WP_088431076.1|4867010_4868057_+|biotin-synthase-BioB	unknown	unknown	gnl|CDD|235755
NZ_CP021983.1|WP_080811277.1|4884621_4885134_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811315.1|4877156_4877588_-|hypothetical-protein	unknown	unknown	gnl|CDD|379326
NZ_CP021983.1|WP_088431078.1|4874085_4875204_-|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NZ_CP021983.1|WP_080811286.1|4872400_4873786_-|MFS-transporter	unknown	unknown	gnl|CDD|349950
NZ_CP021983.1|WP_088431084.1|4892441_4892801_-|transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|197713
NZ_CP021983.1|WP_080811272.1|4887202_4888261_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080811282.1|4876590_4877124_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP021983.1|WP_088431084.1|4892441_4892801_-|transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	7.1e-17	56.6	0.2

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_088431080.1|4875293_4876040_-|DUF4058-domain-containing-protein	gnl|CDD|379094	pfam13267, DUF4058, Protein of unknown function (DUF4058). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 244 and 264 amino acids in length.	7.03439e-103
NZ_CP021983.1|WP_088431082.1|4891823_4892399_-|hypothetical-protein	gnl|CDD|275380	sd00033, LRR_RI, leucine-rich repeats, ribonuclease inhibitor (RI)-like subfamily. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.	3.51844e-12
NZ_CP021983.1|WP_080811290.1|4869744_4870215_-|thioredoxin-dependent-thiol-peroxidase	gnl|CDD|224146	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	7.26882e-83
NZ_CP021983.1|WP_080811274.1|4885749_4887213_-|hypothetical-protein	gnl|CDD|240017	cd04659, Piwi_piwi-like_ProArk, Piwi_piwi-like_ProArk: PIWI domain, Piwi-like subfamily found in Archaea and Bacteria. RNA silencing refers to a group of related gene-silencing mechanisms mediated by short RNA molecules, including siRNAs, miRNAs, and heterochromatin-related guide RNAs. The central component of the RNA-induced silencing complex (RISC) and related complexes is Argonaute. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the 5' anchoring of the guide RNA and the other, the catalytic site for slicing. This domain is also found in closely related proteins, including the Piwi subfamily, where it is believed to perform a crucial role in germline cells, via a similar mechanism.	4.12206e-101
NZ_CP021983.1|WP_080811280.1|4878500_4882442_-|NACHT-domain-containing-protein	gnl|CDD|227922	COG5635, COG5635, Predicted NTPase (NACHT family) [Signal transduction mechanisms].	4.0756e-30
NZ_CP021983.1|WP_080811291.1|4869289_4869745_-|NUDIX-hydrolase	gnl|CDD|223979	COG1051, COG1051, ADP-ribose pyrophosphatase [Nucleotide transport and metabolism].	5.55915e-26
NZ_CP021983.1|WP_088431078.1|4874085_4875204_-|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	4.86153e-18
NZ_CP021983.1|WP_080811293.1|4868467_4869217_+|serine/threonine-protein-phosphatase	gnl|CDD|277316	cd00144, MPP_PPP_family, phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain. The PPP (phosphoprotein phosphatase) family is one of two known protein phosphatase families specific for serine and threonine. This family includes: PP1, PP2A, PP2B (calcineurin), PP4, PP5, PP6, PP7, Bsu1, RdgC, PrpE, PrpA/PrpB, and ApA4 hydrolase. The PPP catalytic domain is defined by three conserved motifs (-GDXHG-, -GDXVDRG- and -GNHE-). The PPP enzyme family is ancient with members found in all eukaryotes, and in most bacterial and archeal genomes. Dephosphorylation of phosphoserines and phosphothreonines on target proteins plays a central role in the regulation of many cellular processes. PPPs belong to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	2.73218e-23
NZ_CP021983.1|WP_080811270.1|4888293_4888557_-|DUF4365-domain-containing-protein	gnl|CDD|379535	pfam14280, DUF4365, Domain of unknown function (DUF4365). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, eukaryotes and viruses. Proteins in this family are typically between 182 and 530 amino acids in length. There is a single completely conserved residue D that may be functionally important.	1.00047e-06
NZ_CP021983.1|WP_088431076.1|4867010_4868057_+|biotin-synthase-BioB	gnl|CDD|235755	PRK06256, PRK06256, biotin synthase; Validated.	8.39619e-163
NZ_CP021983.1|WP_080811315.1|4877156_4877588_-|hypothetical-protein	gnl|CDD|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	0.000269349
NZ_CP021983.1|WP_080811289.1|4870338_4871532_+|HlyC/CorC-family-transporter	gnl|CDD|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	8.97624e-85
NZ_CP021983.1|WP_080811286.1|4872400_4873786_-|MFS-transporter	gnl|CDD|349950	cd06176, MFS_BCD_PucC-like, Bacteriochlorophyll delivery (BCD) family, also called PucC family, of the Major Facilitator Superfamily. The bacteriochlorophyll delivery (BCD) family, also called PucC family, is composed of the PucC protein and related proteins including LhaA (also called ORF477 and F1696) and bacteriochlorophyll synthase 44.5 kDa chain (also called ORF428). These proteins are found in photosynthetic organisms. Rhodobacter capsulatus LhaA and PucC are implicated in light-harvesting complex 1 and 2 (LH1 and LH2) assembly. PucC may function to shepherd or sequester LH2 alpha and beta proteins to facilitate proper assembly, as well as deliver bacteriochlorophyll a to nascent LH2 complexes. The BCD family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.15667e-131
NZ_CP021983.1|WP_088431084.1|4892441_4892801_-|transcriptional-regulator	gnl|CDD|197713	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.	1.12286e-18

Protein sequences

>NZ_CP021983.1|WP_080811315.1|4877156_4877588_-|hypothetical-protein
MLVATDQPDAAWMWDYKLRQSQREARYEAYALEADFLTQGLMFIETQWHRSHLPERFPLVYVEALSSAPWNRFALERPPFYHGVGRLLLMFARRRSLALGYGGRVGLHSLPGAEGFYRRLQMPDYDADPEKEGLVYFEYGAIA
>NZ_CP021983.1|WP_080811282.1|4876590_4877124_-|hypothetical-protein
MDEDRLAKQLAETGNIMDLCQDPAWLEETAQIEKECGGYVEAGLLLREYAMSAQTVTPDQLQQVRLQSVLFAELHQWMSTWQLGLSFEKTYTQARQIVRHHLQSATEEQAAWLKALLTEIEQKLPPEQAPVRSQTIGWFRQVFTTDDWQQLAEIAAQEIYAGVSQLERLHSAQTSSV
>NZ_CP021983.1|WP_088431080.1|4875293_4876040_-|DUF4058-domain-containing-protein
MYNPFPGMNPYLEQPGLWPQVHNRLMVAIADEITPQVAPKYRVSIEERIYTTTEVMPFMGIADVSVTHRREAEPVVQRATTQVAVPRRVKVPLPVEVTERFLEVRLVQTNEVACVIEVLSPSNKRSGEGREAYETKRRKILGSATNLVEIDLLRGGTAMTLMDPAQKPYSILVSASIERPDAELYEFDLRTAMPTFPVPLQPQELIPTVNLQKVFNDVYDRARFDLVIDYEQPVQPQLLLYGIDDVSG
>NZ_CP021983.1|WP_088431078.1|4874085_4875204_-|pentapeptide-repeat-containing-protein
MEVRQFLRQYANGKRSFVWADLRQANLTGVDLREVNLSRANLTEANLSRANLTGANLTRTNLTRTNLTRANLTDAVLRQANLTGALIDLEALEPQAYVGAILPDGTRFELPAIAESEAAEPAPASAEPVAAVSDAASHSQHSDTSQSGTSKAAGDPLLAPAQGTQWQQPPPTRRSILRKRSRSLPWPNLILFGLGYGGLGLFLYLHQAAWIGWPLVWITAFLWLVGEPYLWFMPVAAALAALVTTGLSVVAIAVAGLASLGLFGGLKMLGWPWSRALRDAIWVGGIGAVLVAIASLAFYGRDAYSGGGIILSPTLPLALLILLGSLCIGVGSMAQLQLQEASWVRSHMARLLSLDAGVGLLLGTLVGWLLAH
>NZ_CP021983.1|WP_080811286.1|4872400_4873786_-|MFS-transporter
MLRLGVFNMGLGIMSLLTLGVLNRIMIDELQVPALIAAGTIAVHQFMAPARIWFGQLSDSRPLLGYHRSSYIWLGIMAVAITSFLALQVVWLLGDGIATQGWGPQIYPWVGLLGVMFAIYGLALSATSTPFTALLVDVSDEQTRSRLVGIGWAMLMVGIITGVAITTVVLQAIDLDTSLAELQGSVNRLFIIAPAVVCGLAILSTAGIEKNYSRRRRRSLTADREDKVTLRQAFRVLTASRQTGLFFTFLLVLSLSLFMQDAILEPYGGEVFNMPISETAQLNAAFGLGTLVGIILTGFWIVPRLGKKRTVTYGCLGAALCLLLIGLSGTTAEPVLLLTAVCCFGFASGILTLGAIVLMLDLTVAETAGTFVGAWGLAQAIARGSATVLGGGVLDLGRGLLALAPSGTGGASPTWLAYGLVFFMQAVGMVVAVWLLKRVDIQEFQANAKQAITAALESDMD
>NZ_CP021983.1|WP_080811289.1|4870338_4871532_+|HlyC/CorC-family-transporter
MRIKSTLSTILVGCLPVTLVIPGPLAEVTLTPLLGVVWLDAIALLGLLALSAFFSGSETAITALDNLKLRALIQEQGDPNRLFTLVMKNRTRFITTLLIGNNLVNNLAAILTSNLFAIWFGSAGVGLAAATITFLLLIFGEITPKSLAIHNVMAYFKVAVRPIYWLSRLLASLGIIQLLETITQRAVRLFQGTPVPQHESLRDLELLIEVLGGKGQLDLHKHELLNRALTLDQLTARDVVKPRIEMQTIAHDASLQTLISLCLETGFSRIPVQGGSKDEIVGIVHLKRALQQLTLLRQTGQTDGPISTAIQPPVYVPEVKPITGLLRQMLQQQFHMAIVVDEYGGTVGLVTLEDILEELVGEIYDESDFPARRRLRSAPAAPLPPLVPSPSDRSSHP
>NZ_CP021983.1|WP_080811290.1|4869744_4870215_-|thioredoxin-dependent-thiol-peroxidase
MTINVGDPAPNFSLPDAEGNTVSLSDLRGKRVVLYFYPRDNTPGCTKEACGFRDAYPDYQGQEVVVLGVSTDDAKSHGKFATKFNLPFPLLVDDGGQVASAYGSYGLKKFMGKEYMGISRSTFIIGPDGRIEKIYRQVKPDTHASDVLADLASLST
>NZ_CP021983.1|WP_080811291.1|4869289_4869745_-|NUDIX-hydrolase
MGYLWHPIRVLLGLLLRRPILGTSVIPLLPSGEIVLVRRRDSGRWGLPGGFVDWGEDIVTAARRELAEETGLSWQSLERLVGIYSHPWRDPRFHSVCVALSAQVTGMPQVNDPREILEVRAFSPSRLPLEHLSHDHHRQLQDYFAGAIILA
>NZ_CP021983.1|WP_080811293.1|4868467_4869217_+|serine/threonine-protein-phosphatase
MSRRLFIGDVHGHYDGLMSLLDAIAPAADDQLYFVGDLIDRGAQSADVVDFVRRYATGCVRGNHEQLLMEAFVDGEVHMPRLQGWLHSGGQMTLSSYRTTEQMLEDLEWIRTLPLYIDLETVWLVHAGVDPNRSLEQQSSREMCWIRDSFHYHPQPYFDDKLIITGHTMTFTLPGVAIGQIAQGPGWIDIDTGAYHPRSGWLTAVDPDNQQVYQINVYESRYRCRSWSDAITWVAPKRSQRFWPLALAM
>NZ_CP021983.1|WP_088431076.1|4867010_4868057_+|biotin-synthase-BioB
MTIVDWNRLAERALAGEELEREVARAVLQAEDNQLLEQLAAAYRVRRHYWENRVRLHFLLNAQSGLCPEDCNYCSQSKLSMAEIEKYPFMSQGKILAAAERAHQLQAGTFCMVISGRSPSEKVFNQVLEAVQAVKGRYPMKICACLGLLDQQQTQALAEAGVDRVNHNLNTAEAYHSSICSTHMFQDRVETVTAVQTAGLTTCSGGILGMGETDDDVIDLALSLRRLQVTSVPVNFLIPIPGTPLAEAGTTLTPRQCLRILCLFRLLLPSQEIRIAGGREVHMRQLQPLGLYAANSIFIGDYLTTPGQATRLDFEMIRDAGFVLENADGTPLPAVPVETLIPSAQAAP
>NZ_CP021983.1|WP_080811280.1|4878500_4882442_-|NACHT-domain-containing-protein
MPGALRFLHQRWLLCCQRSCLMGLFSAALTASLLLGSASFMASQAESWATPEALQSSIEERAINHANAGEQMYHDSVYEEFKDNSLGWDRLEILDVYEAKFTEERERLKSDLKEFLPLNWLTGGILLLLGALLTYIRDRVSAGVEAIGNWLYRRVSGNPLLRNLALQKYRNYLKEHLKHLDTPFKIEPPLEMAAVYVPLKVKEWSEAPNHPTDATDIYQALSQQKGLKRLMVTGPPGSGKSVLLKHIAFTYGNDALDLPDNPIPVRLELNTLTGPDLDEVRFVKRLVKVLEDSNFPNAKNFVAQGLQKGKLLLLLDGLDEVSSQVRPQVVRVINEVLRKYTCPAVVTCRTAVYNHEFDLVLNRNRLEVDEFSDRQIRQFLQAWDARMPPEKSVEQLMQELQNRPKIKILAQNPLLLTIIAGLYTEARFILPYSRTKFYQRATGFLLEQRDQEHNIPNQYPMRDKWSVLRKLALAIQDTLDPNNPDRRNIPYTTVLSLINQTLPVLSPKTDDADSILEEIVSRSGLLQKVVMDDGDECYRFAHLTLQEFFAAKALISEDDALVTRFQQDPTAWREVVKLWCGMAKNSTQLIQQVYEQDALTAFECLADAQTVEQDLADQIVTHMMQDLYRATTDDTVARAFGTVAADSRPQSQGQKVFALLSQRLETEAGDVFKAAAVSLSMTNLPQAAEVLATQYRQDPPAISEALIRMGDVAVPDLARLAQSDDLEAVAALHKIATPEAAKALIPLLWRPEPALQTSAAWRLATLLPRFGIEAALKTYDLSAAIKTDDSIQTPEQAQSLSWVWLPFEESGSSAMPVIAGRIAAILSVLLAEIHSRLLDSEDWKEVADPRIIIPLCAIHLRPTGSIGRTPTNKEELKILVDRGFDQAKFKNTAFGKMAVVVRESRNSFWGIQLSTESQEILDKLIGNTRSNDAGSNNERIKRWLILLSGVKRNLQAELLYRLTDNYRLPNDQDWARIFEPAQTYQFAQSVHYWLILGIALFASAGAVAQVFSEMVQQPERIMNGLLALSIVVVLAFWIALWQGMEARLEPLIFRQLGPFGVGTFTHAIQALRTNASFWKSMTLFQKALTSNSMFGVVCGVAVVGGVLTIAVAAGAGAGFNAWWAMAEVVAMAGLTAMTGANTGSWWDRASWAIAMVAVLVIGFWADAADNIAWIGAWAMAWVVASVVAMVGASLSGYGAALLSEIYTLQGKQHSSIPGWKKGVAFFAFPYFCWFPITAIFSFLGLRNLLHSLNWGNWGLAAVIWLSLFSFCSGLWVYGQRKERVASNPLQGILDEDYPQYLPRSNQRRRRKKL
>NZ_CP021983.1|WP_080811279.1|4884278_4884725_-|hypothetical-protein
MGFLNWWKNEASSQEETASQLDLIGDSQVLAPQRKRVDGAIVNKRFTQSIRDNGGAGDVFQRSVVEETRELFDCTVNELYRETGGKKGRRETLPQAAQEAYMVNESLAANELERQIGTIGGDSQDEVNDQIVGSVRQTSKNTRRWLPW
>NZ_CP021983.1|WP_080811277.1|4884621_4885134_-|hypothetical-protein
MIRDILHTRHSGSAMKLLELKDKVWKAWKLFNDASGVITQEVTFVQDVKRFGDRRYKATWIRALAQFTAQASYESCLDAYMLVLDNFNFTTNRWDYEYRHEILDAFLAYPDALDLIRTGLEQLFSSEFAPREREEADGFFELVEERSQQPGRDGLPIRLDWRLPSTSSAA
>NZ_CP021983.1|WP_080811275.1|4885269_4885605_+|hypothetical-protein
MPKLDCCDRCRFYSHTLYLVCANHPKGVETPTCPDFVPDSLRSEEESLAFYEPWQPEDASYYADELILDPIQRLTNAQRLELLDTHPLFTGRCPKCESPIPQTDPPRIHWD
>NZ_CP021983.1|WP_080811274.1|4885749_4887213_-|hypothetical-protein
MKIDFLSEPELEFGNGGRHIDIRFGMMHHKPLDYGTASAPSEIKLGVVGSSETVEGLESWLDKCKQGIEAKKSKQPYLFPEFPGFGEIESLPTNISVNSRRNAIISNKAIDKLLENTDRNLLIKETVDALIEELKYIDEKTGPDVLICALPQSLLERMDEDEADYASQASTKSQRFEKSKAISLDFHDLFKAKAMALRKPTQVVLPSTINLAKKPKKSNRRKNKSLQDEATRAWNLYTALYYKALGTPWRLVRSAQDLATCYVGISFYRTLDRSKLLTSTAQIFNERGEGVILRGGQAEVTKDDRQPYLPATDAAELLANVLSLYRREHRNLPARIVLHKTSRFIPEEFDGFQDALDKHGIDTAEFISFDNRSGTRLFRNGKYPPLRGTLLSLDEQTGVLYTRGSIDFFSTYPGMYVPRPLKFRCESTEDTQKNLAQEILALTKMNWNNTQFDRGEPITIRAARQVGSILKYIGKDEPLEFHYRFYM
>NZ_CP021983.1|WP_080811272.1|4887202_4888261_-|hypothetical-protein
MIIVRVPEREAYWISVKEHFRHSERRKTRKALFDKQANRFDGRVRNALIELAVPRGSGLYLAPRPKKEELYSNLLKVSQFGEKLYTGYTMTEDESRAYTDLLKIGQTLGREWILDGNFILSFHNLRHQPWSTVCDAGTVEEHDVEEWSLSSMRERHHQFVWLLNNTLREKVKGDLLFDRKKECYYFKATPNLSVHTYYYQSLAKKTHRDVFLAYKKKNSEEIAYYRHSAFIGQFLRIDSSWFLEITPTYFFTRDGCTRDKYDQEHLSGIKRLEKNSAVFGQLIMWVEYLSTSPQGELFQLPYPFLTFSKLEKFNINVGIDDAMWIGSEDAESSALLSDDLNELPLFQLDNEN
>NZ_CP021983.1|WP_080811270.1|4888293_4888557_-|DUF4365-domain-containing-protein
MPKKIGKRDITGQKGINVIEEIVLEMGFLWYPTGGVEAGIDGFIEIRDDVTEEVTNSIIQVQGKATEQKNFYQKTILNSNTNVDNET
>NZ_CP021983.1|WP_080811269.1|4889674_4889956_-|hypothetical-protein
MSDSTFKITLGALLVVYLLLFISGPATPWRQSFTFDVAEIVCMALSLAYLYESIKARRGVGMVQARKKFEQNCILYAIAGIALKVISNSQFVT
>NZ_CP021983.1|WP_088431082.1|4891823_4892399_-|hypothetical-protein
MPVGLPLRKLLPFCRFLKSQPNDSHQSPATVLLSDGLLFSLPPQLENVIGDAPLERLRQRLSVCIWEFPDGQPTPKLTTNALSNLPSELAALEHLKVLNLSGNPLGQLPEIIFQLKSLTKLNAIAVNLSEIPESLGQIANLTQLRLDSNQITTIPECIGQLIELEKLDLENNQIGNRPVGIKPQVSPALVY
>NZ_CP021983.1|WP_088431084.1|4892441_4892801_-|transcriptional-regulator
MSDSEEKAMQAIGADAPVSGILSVEKAQRMAEFFGVLGDPNRWRILSALASRELRVGELAEAVEMTESAVSHQLRVLRTMRLVSYRKRGRNVYYCLKDKHIFNLYREASEHLDEPNDDD

Crispr_ID: NZ_CP021983_28

• CRISPR_ID: NZ_CP021983_28
• CRISPR_location: 4961134-4961222
• CRISPR_type: Orphan
• Repeat_type: I-E
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP021983_28

Consensus_repeat	Method
CTGGATTCCCGCCGGCGCGGGAATGAC	CRISPRCasFinder

spacers of NZ_CP021983_28

>28.1|4961161|35|NZ_CP021983|CRISPRCasFinder
TCCTCACTTCTCACTTCTCCCTCCTCCCTTCTCCC

CRISPR arrays and Neighbor proteins around NZ_CP021983_28

CRISPR arrays

The CRISPR arrays of NZ_CP021983_28

>merge|NZ_CP021983|28|4961134-4961222|CRISPRCasFinder
CTGGATTCCCGCCGGCGCGGGAATGACTCCTCACTTCTCACTTCTCCCTCCTCCCTTCTCCCCTGGACTCCCGCCGGCGCGGGAATGAC

>NZ_CP021983|28|29|4961134-4961222|CRISPRCasFinder
CTGGATTCCCGCCGGCGCGGGAATGAC	TCCTCACTTCTCACTTCTCCCTCCTCCCTTCTCCC
CTGGACTCCCGCCGGCGCGGGAATGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP021983.1|WP_080805615.1|4966802_4967366_-|response-regulator	unknown	unknown	gnl|CDD|381085
NZ_CP021983.1|WP_088431124.1|4970079_4970832_+|hypothetical-protein	unknown	unknown	gnl|CDD|99749
NZ_CP021983.1|WP_088431823.1|4965632_4966799_+|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl|CDD|235596
NZ_CP021983.1|WP_080805550.1|4968887_4970003_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270400
NZ_CP021983.1|WP_080805552.1|4967887_4968787_+|lipoyl-synthase	unknown	unknown	gnl|CDD|237261
NZ_CP021983.1|WP_080805574.1|4948053_4948992_+|hypothetical-protein	unknown	unknown	gnl|CDD|379006
NZ_CP021983.1|WP_088431126.1|4970984_4971650_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|368559
NZ_CP021983.1|WP_088431120.1|4961887_4962982_+|sensor-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP021983.1|WP_080805563.1|4958480_4958903_+|response-regulator	unknown	unknown	gnl|CDD|381108
NZ_CP021983.1|WP_088431118.1|4947093_4947666_-|DUF3172-domain-containing-protein	unknown	unknown	gnl|CDD|371494
NZ_CP021983.1|WP_080805565.1|4953656_4958477_+|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|226702
NZ_CP021983.1|WP_080805578.1|4946018_4947053_+|tetratricopeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|276809
NZ_CP021983.1|WP_088431122.1|4963088_4965422_-|DUF4071-domain-containing-protein	unknown	unknown	gnl|CDD|366883
NZ_CP021983.1|WP_080805567.1|4951881_4952487_-|IS630-family-transposase	unknown	unknown	gnl|CDD|315923
NZ_CP021983.1|WP_080805619.1|4945216_4945981_+|RNA-polymerase-subunit-sigma-70	unknown	unknown	gnl|CDD|224511
NZ_CP021983.1|WP_080805561.1|4958905_4960996_+|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|236645
NZ_CP021983.1|WP_080805572.1|4948864_4950703_+|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|223715
NZ_CP021983.1|WP_080805570.1|4950900_4951374_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080805553.1|4967640_4967859_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP021983.1|WP_080805545.1|4971728_4971995_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP021983.1|WP_080805615.1|4966802_4967366_-|response-regulator	gnl|CDD|381085	cd00156, REC, phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response regulators (PRRs). Two-component systems (TCSs) involving a sensor and a response regulator are used by bacteria to adapt to changing environments. Processes regulated by two-component systems in bacteria include sporulation, pathogenicity, virulence, chemotaxis, and membrane transport. Response regulators (RRs) share the common phosphoacceptor REC domain and different effector/output domains such as DNA, RNA, ligand-binding, protein-binding, or enzymatic domains. Response regulators regulate transcription, post-transcription or post-translation, or have functions such as methylesterases, adenylate or diguanylate cyclase, c-di-GMP-specific phosphodiesterases, histidine kinases, serine/threonine protein kinases, and protein phosphatases, depending on their output domains. The function of some output domains are still unknown. TCSs are found in all three domains of life - bacteria, archaea, and eukaryotes, however, the presence and abundance of particular RRs vary between the lineages. Archaea encode very few RRs with DNA-binding output domains; most are stand-alone REC domains. Among eukaryotes, TCSs are found primarily in protozoa, fungi, algae, and green plants. REC domains function as phosphorylation-mediated switches within RRs, but some also transfer phosphoryl groups in multistep phosphorelays.	6.41846e-21
NZ_CP021983.1|WP_088431124.1|4970079_4970832_+|hypothetical-protein	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	5.58945e-07
NZ_CP021983.1|WP_088431823.1|4965632_4966799_+|pyridoxal-phosphate-dependent-aminotransferase	gnl|CDD|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	0
NZ_CP021983.1|WP_080805552.1|4967887_4968787_+|lipoyl-synthase	gnl|CDD|237261	PRK12928, PRK12928, lipoyl synthase; Provisional.	0
NZ_CP021983.1|WP_080805574.1|4948053_4948992_+|hypothetical-protein	gnl|CDD|379006	pfam12974, Phosphonate-bd, ABC transporter, phosphonate, periplasmic substrate-binding protein. This is a family of periplasmic proteins which are part of the transport system for alkylphosphonate uptake.	3.80612e-45
NZ_CP021983.1|WP_088431126.1|4970984_4971650_-|Uma2-family-endonuclease	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	7.08303e-12
NZ_CP021983.1|WP_088431120.1|4961887_4962982_+|sensor-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	6.19226e-44
NZ_CP021983.1|WP_080805563.1|4958480_4958903_+|response-regulator	gnl|CDD|381108	cd17557, REC_Rcp-like, phosphoacceptor receiver (REC) domain of cyanobacterial phytochrome response regulator Rcp and similar domains. This family is composed of response regulators (RRs) that are members of phytochrome-associated, light-sensing two-component signal transduction pathways such as Synechocystis sp. Rcp1, Tolypothrix sp. RcpA, and Agrobacterium tumefaciens bacteriophytochrome response regulator AtBRR. They are stand-alone RRs containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. Also included in this family us Methanosaeta harundinacea methanogenesis regulatory protein FilR2, also a stand-alone RR. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.26469e-61
NZ_CP021983.1|WP_088431118.1|4947093_4947666_-|DUF3172-domain-containing-protein	gnl|CDD|371494	pfam11371, DUF3172, Protein of unknown function (DUF3172). This family of proteins has no known function.	3.41251e-89
NZ_CP021983.1|WP_080805565.1|4953656_4958477_+|PAS-domain-S-box-protein	gnl|CDD|226702	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms].	1.05364e-51
NZ_CP021983.1|WP_080805578.1|4946018_4947053_+|tetratricopeptide-repeat-containing-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	4.79952e-08
NZ_CP021983.1|WP_088431122.1|4963088_4965422_-|DUF4071-domain-containing-protein	gnl|CDD|366883	pfam02026, RyR, RyR domain. This domain is called RyR for Ryanodine receptor. The domain is found in four copies in the ryanodine receptor. The function of this domain is unknown.	1.27183e-27
NZ_CP021983.1|WP_080805567.1|4951881_4952487_-|IS630-family-transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.25946e-23
NZ_CP021983.1|WP_080805619.1|4945216_4945981_+|RNA-polymerase-subunit-sigma-70	gnl|CDD|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	4.48455e-06
NZ_CP021983.1|WP_080805561.1|4958905_4960996_+|PAS-domain-S-box-protein	gnl|CDD|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	4.15653e-115
NZ_CP021983.1|WP_080805572.1|4948864_4950703_+|HAMP-domain-containing-protein	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.5539e-41
NZ_CP021983.1|WP_080805550.1|4968887_4970003_+|ABC-transporter-substrate-binding-protein	gnl|CDD|270400	cd13682, PBP2_TRAP_alpha-ketoacid, Substrate-binding component of an alpha-keto acid binding Tripartite ATP-independent Periplasmic transporter and related proteins; contains the type 2 periplasmic-binding protein fold. This subgroup includes TRAP transporters that bind to ketoacids such as pyruvate and alpha-ketobutyrate, xylulose, and other unknown ligands. TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP; often called the P subunit) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process (the M subunit) and a smaller membrane of unknown function (the Q subunit). The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	0

Protein sequences

>NZ_CP021983.1|WP_080805561.1|4958905_4960996_+|PAS-domain-S-box-protein
MSDSLRVLIVEDAEDDALLVLRELRRGNFDLVWERVQTAESLRTLLTTRAWDVIISDYRLPGFDAPAALEIVKQSQLDIPFIMVSGTIGERSAVEIMKAGAHDYLMKDNLVRLPEAVRRELRDAQIRAERKQAEVALRRQLAAIEAAIDGIGILQGDTYLYLNQAYLNLFGYDHAEELVGKTWRLCYSQVEIDRFEQEVFPVLDRDRAWQGEAIATRKDGSTFAQGVSLTLTEDGLLISVCRDISDLKQAQEMLIYIALHDPLTGLPNRKLLIERLELAINRARRLENYHYAVLFLDLDRFKVINDSLGHSVGDQLLIAIAQRLKVHVRDIDLVARLGGDEFVILLEEISGPEDVIQISERILADFQTPFIIHDYEIFTSFSIGIVLGTQDYHQTSDLMRDADIAMYRAKAQQNNSYKFFDAAMHTQALNRLTLETDLRKALNQQEFVVYYQPIFDLFNHRLFGFEALVRWQHPTRGFISPDEFISIAEETGFIVPLDNWVLYNACQQIASWENQFANGSSFKISINLSAQDLRKVNLIQDVDDILADTGLAGHSLTLEITESLLIENIDQTIDLLVQLASRNIQISIDDFGTGYSSLGYLHRFPVNNLKIDRSFVDQIQSESREYHVVDTIIALGQHLGLSVIAEGVETTQQLEWLQQLRCEFGQGYLFSKPLAAAEIERRYLARLEETYNSNEG
>NZ_CP021983.1|WP_080805563.1|4958480_4958903_+|response-regulator
MATPRPILLVEDNPDDERLTLRALRQGKVTNPIQVARNGEEALTVLFSADPLPTVVLLDLKLPKIDGLEVLRRIRGHDRTRLLPVVVLTSSSEERDIVESYSLGANSYVRKPVDFDQFTNAISQLGLYWVLINEPLPESL
>NZ_CP021983.1|WP_080805565.1|4953656_4958477_+|PAS-domain-S-box-protein
MLDTLLLIPHGHCYLWKPNLVGLHVVSDALIGIAYYSIPLTLLYFVQKRKDVPFDWIFLLFSAFIAFCGTTHLMSIWTLWHPAYWVSGTIKALTAAISVYTAIQLIPIVPKALDLPSPAQLEAINHQLQQHVAKREQAERHLRQLSARLNLAVKSAAIGIWDWDMTQDILTWDKRMYELYGLIPECFTPAYGAWSSCLHPDDRRAAEMAAQQALQGEKDFDQDFRVVHPDGSIHYIKANALVQRDPHGDPQRMIGVSYDITDRKQAEQQLQQLNQALEAKVEERTRELQALARREQLSANIATQIRSSLDLQVILETAVREIRSLLQCARVNIWRFDADGQTMVVAESTDSSLSLVGERVNDTCLQDYTALYRQGRVRIVPDIYTTDMSACHRELLIRSQIRAKILVPLLCGDELWGLLHVSESQHPRDWQPEEVELLQALSVQLGIALQQATIHQQLQAELNERQQTEARLRASEQRYITLAAAVPVGIYRTDAAGNCLYVNDRLGQITGLAPEATMGQGWRQGLHPDDRDRVVTEWYQSAQENRPFQLEYRFQHPDGTVRWVYGQSVAEWDADGQVIGYVGTITDISERKRLEAERKQVEAERLQAKQTRKELTLLEQILDIILAGYWDWDIPGNQEYLSLGFKQMFGYADHELPNTPETWQNLIFPQDLPGVLECFNRHVQSRGEVPYVNEVRYRHKDGSTVWVICSSKVIEWDEAGNPLRMIGCHIDISDRKRAEAALISSEARLQYLVSSSPVVIFSCKPNGDYGATFISENVEALLGWNAQDFLADSEFWLNHLHPDDAERVLAGLANLFTGDFYAHEYRLRKGDDTYCWCLAQLRLIRDQAGNPLEMLGYLIDISDRKHTEAALRDSEARLQLITDSIPGCISYTDASQHYRFVNHTYEEWFGCRKEDILERSIAEVLGAEAYQRARQHIERVLSGETVTYENELPYQGRQPRYVSGKLVPEIDSQGRVHGYYALITDISDLKQAEAALKASRAYYQGIVSDQTELICRFLPDGILTFVNDAYCQFFQKSPEDLLGRSFTPLIPAEDKEIALQTFNSLSVDNPVVTCEHRVIAPDGSIRWQQWTDRALVDPDGNFIEFQAVGRDITALKEAEADIKRHLTAIEAAIDGISILRDGHYSYLNQSQLTLFGYSQAEDLLGQSWQVLYPAQEVRRFQKEVLPQVKQHGFWHGEATGKRRDNTLFPVEVSLTLTPTGDIIRVCRDISDRKQAEDHLRQMSVRLNLAVKSAAMGIWDWDVTHNILTWDQQMYELYGITPEQFTNVYEAWSSSVHPDDLAAAETAVQQALRGEKDFDQDFRVIHPDGTIRFIKANALVQRNRHGDPEWMIGINYDITARKRTEAQIQEYATQLESSNRELEAFAYSVSHDLRAPLRAIDGFSKALLEDYGDTFDEEGQDYFDRIRKNVTRMGMLIDDLLSLSRVSRYEIRHTTVNLSTLAQELMAELQASEPERPVEVGIAPDAIVSADATLMRVVLTNLLQNAWKFTSHHPTARIEFGMIYPDGQPVYFVRDDGAGFDMAYSNMLFGVFQRLHNIHEFPGTGIGLATVQRAIHRHGGRVWAEATVEQGATFYFTLPSTPLELGA
>NZ_CP021983.1|WP_080805567.1|4951881_4952487_-|IS630-family-transposase
MTGIQALERTMPDIAMKPGRCVRVEFEYIRHGTQALIASLNVATGRIDQATVGDTRTEQDLDTHLRALLAQSPEAPKIHLVMDCLNTHQSESLVRLAAELEPEPLALGVKGKSGILQSMATRAAFLTNAAHRLVVHFTPKHCSWLNQIGIWFSILVRKLLRRSSFKSQAELRAKILDFVDYFNRTMAKPFKWNYTGKPLTA
>NZ_CP021983.1|WP_080805570.1|4950900_4951374_+|hypothetical-protein
MVTNRVSATLDSSELQTMMAAIATIPEKLSFFAGLTPEERKSLLKMADTNEAFARRALEVATQTPDFLPCSFDLEEMQRDLTLFTSLQPVILAVTQLQEMLTYTATAAGNEAYTAALEVYRYAKANGTMAGLDDLVEKLGEWFTKRANPKGSQPVTE
>NZ_CP021983.1|WP_080805572.1|4948864_4950703_+|HAMP-domain-containing-protein
MRRQPGVMSCSNLKRQLSSMSFPREPVLPLLGSKCYMTWWAINKTRALRLPGWQRWSPQRSLGVKLTMTMTGLVVIAISGVTALSVQREQNTFHQEWKERASLLLDTLEVVARDPLYDLEADVLSQLISALAQNHPLLTSGHIYDSDGRIIADLHRQGPVYATQSSPLGQRLINSEPTVFIWQSQQLVAGRAIIAGEQRLGAVSIGLSTAPLQQKVARVRNQGIVIALIAGGLGASIAVVLSRSITTPLQALVVATRKIAQGDLNQQVPIQSHDELAVLAQSFNEMTSRLQQTLSLLQAHKDELEQRVQERTQALSEAIQHLQQTQTQLVQSEKMSSLGQLVAGVAHEINNPASFIHGNLTYASTYIQDLLDIITLYQRHYPNPPAGLQEAIDAVDLAFIQSDLPKLLQSMQVGSDRINEIVRSLRTFSRLEEGDFKPADIHDGIDSTLMILKHRLKMATGNGIQVVKHYAPLDPIDCRLGQLNQVFMNILTNAIDALQDQEAAPSSPSQQPPTIEIRTRSLSPDWIAIHIFNNGPSIDTEIHSKLFDPFFTTKSVGQGTGLGLSISYQIVTEHHRGRLYCHSKANWGTEFILELPTHHPDETMPDLAAADR
>NZ_CP021983.1|WP_080805574.1|4948053_4948992_+|hypothetical-protein
MLHLWLKIILGLGVILGVSGCSPDSLSSDTTSPAADPAATETFVIADISDEPAAKIDAYQPMANYLAEQLSEFGIEAGAVKVAPDMATMTQWLATGDVDLYFDSPYPAMRVKTGSGATVLLRRWKTGVAAYSTILFARQDSNRQTVHDLLGQVVAFEEEFSTSGYMLPKAYLAEAGLSLTQLNDPTAQVPPDQIGYVFSRHEQTTIQWVLSQRVVAGAVGSPYFYSIPESTREQLVILAETEALPRHIGLVSPTMDAAQQQALKTVLMAMDETPAGRDVLQQFEETAQFDEFPQGASTAIARIKVLYDLVGD
>NZ_CP021983.1|WP_088431118.1|4947093_4947666_-|DUF3172-domain-containing-protein
MRRTRPSRSSKSYDSYRSTEPPPPKSPLGSTLNYMTLAIIGGVFILGIGLGIAFSSSTTSMTPQNVASREFIDRRAPNPEMCVQYGASAVVADARIFLTFNPFGVYLSQPTMQPGCVIRRNNWAVLEKRGLIDSEDERQCRQRMNTFGYTGDANNEQAAKVDCIYQNDAAGNLFLNQQGAGAPPPGTENF
>NZ_CP021983.1|WP_080805578.1|4946018_4947053_+|tetratricopeptide-repeat-containing-protein
MATPKRWPYGWLLVVLTLGFVGPSALATDLDQQLDIRPFNATAGQPRNVADQWLRLGSQQATAGRPAEAIASWQQAIEIYHALGDTVALGLTYDYIGLTFASLGQYDQAESALRRRLAIARDNQNLQREIFGWNNLGSLLLQQGNVAAAQAAFSEASVLARSVNHPEGLGLSLSNLGLVAAIQGQWQDARKYYETAAGYRYTAADWAGEAHTSNGLGDVYQALDQESAAIGAYRLALRLARDVNDVAVQLRAIDGLLPIYLDRNELTTVRRLIDQRLALTLGANDPQTVVSLMYAGDYYRRSGDIAAARTLYYRGMQLAAALEMKLEQADLANRLVQLGGLPVL
>NZ_CP021983.1|WP_080805619.1|4945216_4945981_+|RNA-polymerase-subunit-sigma-70
MRIPSFPECDHEIVQSLFHLSDRELVSLLKHHPDSGRYFTAIFCRYSPIVYSLIRHSARSPVQADYLFAITWRHILYELSGLDWPEAVPGKSSFSLQSWLINITALCINQVPLPDVEQIHYAIEDASPPLWCYLERALENLPPIERLMVVMAQTFHWSATRIAAYLQAEGERLSPGDVKSRLQDAYRHLEEALPTDIRAIYLGAAGTDNGYQEGNESDENDEDERLLDQVFAPNEPSADRSYLQLMLQGKKAAL
>NZ_CP021983.1|WP_088431120.1|4961887_4962982_+|sensor-histidine-kinase
MQALVVATRKIAQGDLNQQVPIQSHDELAVLAQSFNEMTSRLQQTLSLLQAHKDELEQRVQERTQALSEAIQHLQQTQTQLVQSEKMSSLGQLVAGVAHEINNPASFIHGNLTYASTYIQDLLDIITLYQQHYPNPPAGLQEAIDAVDLAFIQSDLPKLLQSMQVGSDRINEIVRSLRTFSRLEEGDFKPADIHDGIDSTLMILKHRLKMATGNGIQVVKHYAPLDPIDCRLGQLNQVFMNILTNAIDALQDQGAAPSSPSQQPPTIEIRTRSLSPDWIAIHIFNNGPSIDTEIHSKLFDPFFTTKSVGQGTGLGLSISYQIVTEHHRGRLYCHSKANWGTEFILELPTHHPDETMPDLAAADH
>NZ_CP021983.1|WP_088431122.1|4963088_4965422_-|DUF4071-domain-containing-protein
MDASAVVTPQWRKSEGDPQRSGKRCRGQEQPVYQPQPIDTSQATLTAEYLYLAERLAENSHDHWAQALLGLGWRYGTRLNAAERTHPYLCPFEQLPEAVQEQQLQVYLDNLKTAVALGYRIEAQPVAPPRIKLGTAEAATATLRIGAGAMPRQLAPLLALRREIVTLRPRTPDLHCSLGEMMLQLGETLMAYDVLADGLKQWPQHLRLQQLLALALARSGATHAANEVLGQLMAAGQDDDETLSLLARTHKDLWRQAGPDQMRSHHLKLAADRYLEAYRRSGSLWPGINAATLSLLQGNRGQARQLATAVAETARQALEQATKTGQDTYWILATLGEAELVLGRYDQAAAYYTQAVQVGQGRFGDLGSSYRNAALLMQHLGQGLDPLREWFQMPRVIVFCGHRMDAANRPQPRLPPVLEDSVYDAIHTRLQQLNGRVGYASAACGSDILFLEALLELGGECNIVLPYNRDQFIQDSVSTATAGDWVARFDRVLSQAREVVVASDCKPQADDVSYEYSNRLLHGLAKIRAEQLYTDLVPLAVWNGQPGDGPGGTASTVAYWQQWSHQVEIIDSAALLAAAGYDTESEPRSTPTAALEQQQREIRALLFADVVQYTQLLEDQLCIFMRHFLEAVAALSNQPRYQPLTKNTWGDALYYVFPTVQEAGLFALDLGDLMQSIDWQQQGLPADLTIRIALHAGPVLRNVDPITNQVNYMGTHVNHAARIEPITPPGKVYASQAFAAIATSEGQQSFTCSYVGRMPWAKHYGTFPTYHVQRLHS
>NZ_CP021983.1|WP_088431823.1|4965632_4966799_+|pyridoxal-phosphate-dependent-aminotransferase
MTIADRVNRVTPSMTLAISAKAKAMKAEGLDVCSFSAGEPDFDTPDHIKAAAKQALDQGKTRYGPAAGEPALRRAIAQKLQQDNDLCYGPENIIVTNGGKHSLYNLMMTLIGPGDEVIIPAPYWVSYPEMVTLAGGTPVIVPTDLAGGYKITPEQLRRHITPQTRLFILNSPSNPTGTVYSPEEIKALAEVVIEADIWVVSDEIYEKIRYDDVPHLSIGAIGPEAYQRTLLSNGFAKAYAMTGWRIGYLAGPVELIRAMNTLQSHSTSNVCTFAQYGAIAALEGPQDCIATMGHAFAQRRQVMLKAIHSIPGLSCATPQGAFYLYVDISALAVPSLDFCSQLLEEKYVATIPGVAFGAEGSIRLSYATDLETIERGLERLAAFVRSRS
>NZ_CP021983.1|WP_080805615.1|4966802_4967366_-|response-regulator
MASHKILVIDDSRVIRMRVRDMLPQGNFEVIEAQDGVEGMSAIQDQRPNLIMLDFLLPRKSGWEVFQEIQARPDLQHIPLVLMSGRKEEVTEKIQEPFEYFEFIQKPFDQKELIGAIKGAMAKARKARPAQAAAPAAEAPPGEAAAGGIDPADYQALVAKVNHLQAEVNQLKGQLAKMLAFIKQKLK
>NZ_CP021983.1|WP_080805553.1|4967640_4967859_+|hypothetical-protein
MNPRLAPVEPPCEHHKRFALVVGVRGEHRGKEEGKGQKAEGFNSKFKIYCYLAEATRAAAANPQALPCMDLQ
>NZ_CP021983.1|WP_080805552.1|4967887_4968787_+|lipoyl-synthase
MSPQPQSSPAPELTQLPTWLKRPIGKASELSRVQKIIKQRQIHTICEEGRCPNRGECYAQGTATFLLMGPTCTRSCAFCQVDKGHAPMALDPEEPRKVAESVQLLGLRYVVLTSVARDDLPDQGAAWFVQTMAAIRAICPETQIEVLTPDFWGGPEPQRQQYQRLATVVGAGPACFNHNIETVQRLQGPVRRGAKYERSLDVLRQVKAIDSSVPTKSGLMLGHGETEAEVIEALADLRAVACDRITLGQYMRPSLAHRPVQHYWTPEAFERLGAMATTMGFAHVRSGPLVRSSYHAGEA
>NZ_CP021983.1|WP_080805550.1|4968887_4970003_+|ABC-transporter-substrate-binding-protein
MKRRHIIRYGAGAAGVAALAACNANTDTASAPTSTTGSDLPQVRWRMATSWPQSLDTIFGGAQTVCDRVSALSGGRFTIEPYAAGEIVPGLQVLDAVQSGTVECGHSASYYYVGKNPALAFGTTVPFGLNAQQQNAWFYHGGGLDTMHRLYADFGVINFPAGNTGTQMGGWFKQPINSVSDLQGLKMRIPGLGGEVMSRLGVNVQVLPGGEIFLALDRGAIDAAEWVGPYDDEKLGLNDAAQYYYYPGWWEPGATLEAQVNLQAWESLPQEYQEIFKTAAYEANINMLAQYDSLNGAALQRLMDGGTQLTPYSDEIMAAAEAASLEFYEENANQDATFKEVYEQWRTFRQEVYAWNRVNELSFARFSNRES
>NZ_CP021983.1|WP_088431124.1|4970079_4970832_+|hypothetical-protein
MVDQLAISEEVAFPDASQLVTEDDTPVDNFASAKQQRLLVSSLYSALLGQVFLAEANVGIYHIFSQPPIVPDVFVSFNVQVPQDWWEKQNRCYLVWNFGKPPEIVIEVVSNQVGNELTDKFATYEHMRVSYYAVYDPSLQLSETPLRLFELRGMHYTEMTEPWLEQVGLGLTTWQGDFEGRQDTWLRWCNAEGAMLLTGDEQAAQARQQAEQERQRAEQERQRAEQERQRADRLADLLRAQGIDPDQLPQ
>NZ_CP021983.1|WP_088431126.1|4970984_4971650_-|Uma2-family-endonuclease
MVLISTQISELDLDNFDGQLTQTVVLSNISWQTYRAMLADLGDHRATRIAYNQGVLTLKMPSKLHEIINRLLGQIVTTLTEVLGLEVLNVGSMTLNRPDLQQGAEPDTGFYIQHAPQLEGLDPVIPEKLPPDLVIAVGITSPSTQRLHIYAALEVPEVWRYSKRQGLVIYQLTPTGYAASAVSLAFPQVTAADLNGFLEQRQSQSENQVMRSVRHWSQSLA
>NZ_CP021983.1|WP_080805545.1|4971728_4971995_+|hypothetical-protein
MAETIEQVTMQAYKVAATVSENGTLVLRGLPFQAGRVVEVIVLEQISVAPAEHSPQEQTSLDHDYLLGVETQMSEWASAEDEAAYHDL

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP021983_2	2.2|497596|29|NZ_CP021983|CRT	497596-497624	29	NZ_CP021983.1	138399-138427	0	1.0
NZ_CP021983_2	2.3|497664|32|NZ_CP021983|CRT	497664-497695	32	NZ_CP021983.1	1212532-1212563	0	1.0
NZ_CP021983_2	2.3|497664|32|NZ_CP021983|CRT	497664-497695	32	NZ_CP021983.1	1705852-1705883	0	1.0
NZ_CP021983_2	2.5|497596|33|NZ_CP021983|CRISPRCasFinder	497596-497628	33	NZ_CP021983.1	138399-138431	0	1.0
NZ_CP021983_2	2.6|497664|36|NZ_CP021983|CRISPRCasFinder	497664-497699	36	NZ_CP021983.1	1212532-1212567	0	1.0
NZ_CP021983_2	2.6|497664|36|NZ_CP021983|CRISPRCasFinder	497664-497699	36	NZ_CP021983.1	1705852-1705887	0	1.0
NZ_CP021983_2	2.7|497597|28|NZ_CP021983|PILER-CR	497597-497624	28	NZ_CP021983.1	138400-138427	0	1.0
NZ_CP021983_2	2.8|497665|31|NZ_CP021983|PILER-CR	497665-497695	31	NZ_CP021983.1	1212533-1212563	0	1.0
NZ_CP021983_2	2.8|497665|31|NZ_CP021983|PILER-CR	497665-497695	31	NZ_CP021983.1	1705853-1705883	0	1.0
NZ_CP021983_14	14.2|2245425|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR	2245425-2245461	37	NZ_CP021983.1	1276826-1276862	0	1.0

1. spacer 2.2|497596|29|NZ_CP021983|CRT matches to position: 138399-138427, mismatch: 0, identity: 1.0

atcactcagactcagctagaacaggcgct	CRISPR spacer
atcactcagactcagctagaacaggcgct	Protospacer
*****************************

2. spacer 2.3|497664|32|NZ_CP021983|CRT matches to position: 1212532-1212563, mismatch: 0, identity: 1.0

agttggtcagtcttcggatgacgctagcgacc	CRISPR spacer
agttggtcagtcttcggatgacgctagcgacc	Protospacer
********************************

3. spacer 2.3|497664|32|NZ_CP021983|CRT matches to position: 1705852-1705883, mismatch: 0, identity: 1.0

agttggtcagtcttcggatgacgctagcgacc	CRISPR spacer
agttggtcagtcttcggatgacgctagcgacc	Protospacer
********************************

4. spacer 2.5|497596|33|NZ_CP021983|CRISPRCasFinder matches to position: 138399-138431, mismatch: 0, identity: 1.0

atcactcagactcagctagaacaggcgctgaag	CRISPR spacer
atcactcagactcagctagaacaggcgctgaag	Protospacer
*********************************

5. spacer 2.6|497664|36|NZ_CP021983|CRISPRCasFinder matches to position: 1212532-1212567, mismatch: 0, identity: 1.0

agttggtcagtcttcggatgacgctagcgaccgaag	CRISPR spacer
agttggtcagtcttcggatgacgctagcgaccgaag	Protospacer
************************************

6. spacer 2.6|497664|36|NZ_CP021983|CRISPRCasFinder matches to position: 1705852-1705887, mismatch: 0, identity: 1.0

agttggtcagtcttcggatgacgctagcgaccgaag	CRISPR spacer
agttggtcagtcttcggatgacgctagcgaccgaag	Protospacer
************************************

7. spacer 2.7|497597|28|NZ_CP021983|PILER-CR matches to position: 138400-138427, mismatch: 0, identity: 1.0

tcactcagactcagctagaacaggcgct	CRISPR spacer
tcactcagactcagctagaacaggcgct	Protospacer
****************************

8. spacer 2.8|497665|31|NZ_CP021983|PILER-CR matches to position: 1212533-1212563, mismatch: 0, identity: 1.0

gttggtcagtcttcggatgacgctagcgacc	CRISPR spacer
gttggtcagtcttcggatgacgctagcgacc	Protospacer
*******************************

9. spacer 2.8|497665|31|NZ_CP021983|PILER-CR matches to position: 1705853-1705883, mismatch: 0, identity: 1.0

gttggtcagtcttcggatgacgctagcgacc	CRISPR spacer
gttggtcagtcttcggatgacgctagcgacc	Protospacer
*******************************

10. spacer 14.2|2245425|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR matches to position: 1276826-1276862, mismatch: 0, identity: 1.0

cgaagccgctaaacagggtactgcaacgggtatccag	CRISPR spacer
cgaagccgctaaacagggtactgcaacgggtatccag	Protospacer
*************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP021983_11	11.1|1482385|26|NZ_CP021983|CRISPRCasFinder	1482385-1482410	26	NZ_CP026518	Deinococcus sp. NW-56 plasmid unnamed2, complete sequence	156358-156383	3	0.885
NZ_CP021983_11	11.1|1482385|26|NZ_CP021983|CRISPRCasFinder	1482385-1482410	26	CP054927	Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence	351092-351117	4	0.846
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024790	Nostoc flagelliforme CCNUN1 plasmid pNFSY05, complete sequence	34539-34572	5	0.853
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024791	Nostoc flagelliforme CCNUN1 plasmid pNFSY06, complete sequence	111675-111708	5	0.853
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	314746-314779	5	0.853
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	500244-500277	5	0.853
NZ_CP021983_5	5.1|805981|31|NZ_CP021983|CRISPRCasFinder	805981-806011	31	NZ_AP022622	Mycobacteroides abscessus strain JCM 30620 plasmid pJCM30620_1	77940-77970	6	0.806
NZ_CP021983_5	5.1|805981|31|NZ_CP021983|CRISPRCasFinder	805981-806011	31	NC_021279	Mycobacteroides abscessus subsp. bolletii 50594 plasmid 2, complete sequence	57240-57270	6	0.806
NZ_CP021983_11	11.1|1482385|26|NZ_CP021983|CRISPRCasFinder	1482385-1482410	26	MN585966	Gordonia phage Faith5x5, complete genome	37478-37503	6	0.769
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024791	Nostoc flagelliforme CCNUN1 plasmid pNFSY06, complete sequence	200901-200934	6	0.824
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	260797-260830	6	0.824
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NC_009926	Acaryochloris marina MBIC11017 plasmid pREB1, complete sequence	223917-223950	6	0.824
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP050442	Tolypothrix sp. PCC 7910 plasmid unnamed2, complete sequence	56819-56852	6	0.824
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_CP023279	Nostoc sp. CENA543 plasmid pCENA543c, complete sequence	26983-27018	6	0.833
NZ_CP021983_11	11.1|1482385|26|NZ_CP021983|CRISPRCasFinder	1482385-1482410	26	NC_023283	Streptomyces sp. FR1 plasmid pFRL3, complete sequence	60608-60633	7	0.731
NZ_CP021983_14	14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR	2246065-2246101	37	NZ_CP018229	Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence	248130-248166	7	0.811
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	121210-121243	7	0.794
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	317585-317618	7	0.794
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	503114-503147	7	0.794
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NC_007410	Trichormus variabilis ATCC 29413 plasmid A, complete sequence	266582-266615	7	0.794
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP047243	Trichormus variabilis 0441 plasmid unnamed1, complete sequence	272307-272340	7	0.794
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_CP011314	Klebsiella pneumoniae subsp. pneumoniae strain 234-12 plasmid pKpn23412-362, complete sequence	49705-49740	7	0.806
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_LT883139	Escherichia coli isolate 6666666.257727.embl plasmid I	53350-53385	7	0.806
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_CP034054	Klebsiella pneumoniae strain KP_NORM_BLD_2015_112126 plasmid unnamed1, complete sequence	292034-292069	7	0.806
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_CP034046	Klebsiella pneumoniae strain KP_NORM_BLD_2014_104014 plasmid unnamed1, complete sequence	338621-338656	7	0.806
NZ_CP021983_2	2.1|497526|31|NZ_CP021983|CRT	497526-497556	31	NZ_CP021794	Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence	186871-186901	8	0.742
NZ_CP021983_2	2.1|497526|31|NZ_CP021983|CRT	497526-497556	31	NZ_CP019585	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymA, complete sequence	489758-489788	8	0.742
NZ_CP021983_2	2.1|497526|31|NZ_CP021983|CRT	497526-497556	31	NC_017327	Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence	1139257-1139287	8	0.742
NZ_CP021983_2	2.1|497526|31|NZ_CP021983|CRT	497526-497556	31	NZ_CP021217	Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence	725661-725691	8	0.742
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024790	Nostoc flagelliforme CCNUN1 plasmid pNFSY05, complete sequence	34064-34097	8	0.765
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024790	Nostoc flagelliforme CCNUN1 plasmid pNFSY05, complete sequence	95469-95502	8	0.765
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024791	Nostoc flagelliforme CCNUN1 plasmid pNFSY06, complete sequence	111200-111233	8	0.765
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024791	Nostoc flagelliforme CCNUN1 plasmid pNFSY06, complete sequence	120043-120076	8	0.765
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024791	Nostoc flagelliforme CCNUN1 plasmid pNFSY06, complete sequence	174393-174426	8	0.765
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024791	Nostoc flagelliforme CCNUN1 plasmid pNFSY06, complete sequence	114495-114528	8	0.765
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	315221-315254	8	0.765
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	374719-374752	8	0.765
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	408851-408884	8	0.765
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	500719-500752	8	0.765
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	236687-236720	8	0.765
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	586677-586710	8	0.765
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NC_009926	Acaryochloris marina MBIC11017 plasmid pREB1, complete sequence	223924-223957	8	0.765
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_AP017296	Nostoc sp. NIES-3756 plasmid pNOS3756_1, complete sequence	221527-221560	8	0.765
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_AP017296	Nostoc sp. NIES-3756 plasmid pNOS3756_1, complete sequence	393399-393432	8	0.765
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NC_007410	Trichormus variabilis ATCC 29413 plasmid A, complete sequence	259111-259144	8	0.765
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP047243	Trichormus variabilis 0441 plasmid unnamed1, complete sequence	264836-264869	8	0.765
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_CP011314	Klebsiella pneumoniae subsp. pneumoniae strain 234-12 plasmid pKpn23412-362, complete sequence	49698-49733	8	0.778
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	AP018321	Nostoc sp. HK-01 plasmid plasmid3 DNA, complete genome	2088-2123	8	0.778
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_LT883139	Escherichia coli isolate 6666666.257727.embl plasmid I	53357-53392	8	0.778
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_LT883139	Escherichia coli isolate 6666666.257727.embl plasmid I	53364-53399	8	0.778
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_LT883139	Escherichia coli isolate 6666666.257727.embl plasmid I	53371-53406	8	0.778
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_LT883139	Escherichia coli isolate 6666666.257727.embl plasmid I	53378-53413	8	0.778
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_LT883139	Escherichia coli isolate 6666666.257727.embl plasmid I	53385-53420	8	0.778
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_LT883139	Escherichia coli isolate 6666666.257727.embl plasmid I	53392-53427	8	0.778
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_LT883139	Escherichia coli isolate 6666666.257727.embl plasmid I	53399-53434	8	0.778
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_LT883139	Escherichia coli isolate 6666666.257727.embl plasmid I	53406-53441	8	0.778
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_CP034054	Klebsiella pneumoniae strain KP_NORM_BLD_2015_112126 plasmid unnamed1, complete sequence	291999-292034	8	0.778
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_CP034054	Klebsiella pneumoniae strain KP_NORM_BLD_2015_112126 plasmid unnamed1, complete sequence	292006-292041	8	0.778
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_CP034054	Klebsiella pneumoniae strain KP_NORM_BLD_2015_112126 plasmid unnamed1, complete sequence	292013-292048	8	0.778
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_CP034054	Klebsiella pneumoniae strain KP_NORM_BLD_2015_112126 plasmid unnamed1, complete sequence	292020-292055	8	0.778
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_CP034054	Klebsiella pneumoniae strain KP_NORM_BLD_2015_112126 plasmid unnamed1, complete sequence	292027-292062	8	0.778
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_CP034046	Klebsiella pneumoniae strain KP_NORM_BLD_2014_104014 plasmid unnamed1, complete sequence	338586-338621	8	0.778
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_CP034046	Klebsiella pneumoniae strain KP_NORM_BLD_2014_104014 plasmid unnamed1, complete sequence	338593-338628	8	0.778
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_CP034046	Klebsiella pneumoniae strain KP_NORM_BLD_2014_104014 plasmid unnamed1, complete sequence	338600-338635	8	0.778
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_CP034046	Klebsiella pneumoniae strain KP_NORM_BLD_2014_104014 plasmid unnamed1, complete sequence	338607-338642	8	0.778
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_CP034046	Klebsiella pneumoniae strain KP_NORM_BLD_2014_104014 plasmid unnamed1, complete sequence	338614-338649	8	0.778
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_CP024792	Nostoc flagelliforme CCNUN1 plasmid pNFSY07, complete sequence	283983-284018	8	0.778
NZ_CP021983_3	3.50|705040|34|NZ_CP021983|CRISPRCasFinder	705040-705073	34	NC_016585	Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence	662691-662724	9	0.735
NZ_CP021983_14	14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR	2246065-2246101	37	NC_019387	Thermus oshimai JL-2 plasmid pTHEOS01, complete sequence	120696-120732	9	0.757
NZ_CP021983_14	14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR	2246065-2246101	37	NZ_LR594660	Variovorax sp. PBL-H6 plasmid 2	42943-42979	9	0.757
NZ_CP021983_14	14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR	2246065-2246101	37	NZ_LR594667	Variovorax sp. SRS16 plasmid 2	757423-757459	9	0.757
NZ_CP021983_14	14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR	2246065-2246101	37	NZ_LR594690	Variovorax sp. WDL1 plasmid 2	773187-773223	9	0.757
NZ_CP021983_14	14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR	2246065-2246101	37	NZ_LR594672	Variovorax sp. PBL-E5 plasmid 2	757557-757593	9	0.757
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	374712-374745	9	0.735
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	NZ_CP024788	Nostoc flagelliforme CCNUN1 plasmid pNFSY03, complete sequence	54568-54601	9	0.735
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	AP018320	Nostoc sp. HK-01 plasmid plasmid2 DNA, complete genome	75263-75296	9	0.735
NZ_CP021983_14	14.28|2247275|34|NZ_CP021983|CRT	2247275-2247308	34	JQ062992	Bacillus phage phIS3501, complete genome	23327-23360	9	0.735
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NC_010631	Nostoc punctiforme PCC 73102 plasmid pNPUN01, complete sequence	46789-46824	9	0.75
NZ_CP021983_3	3.49|704969|35|NZ_CP021983|CRISPRCasFinder	704969-705003	35	MN234235	Mycobacterium phage BogosyJay, complete genome	50383-50417	10	0.714
NZ_CP021983_3	3.49|704969|35|NZ_CP021983|CRISPRCasFinder	704969-705003	35	MN234200	Mycobacterium phage Maminiaina, complete genome	50365-50399	10	0.714
NZ_CP021983_3	3.55|705408|35|NZ_CP021983|CRISPRCasFinder	705408-705442	35	KC847113	Bacillus phage PBP180, complete sequence	7052-7086	10	0.714
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	252125-252160	10	0.722
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	475675-475710	10	0.722
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_CP023279	Nostoc sp. CENA543 plasmid pCENA543c, complete sequence	27145-27180	10	0.722
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_CP024790	Nostoc flagelliforme CCNUN1 plasmid pNFSY05, complete sequence	67773-67808	10	0.722
NZ_CP021983_25	25.1|4121072|36|NZ_CP021983|CRISPRCasFinder	4121072-4121107	36	NZ_AP014816	Geminocystis sp. NIES-3708 plasmid pGM01, complete sequence	10577-10612	10	0.722
NZ_CP021983_2	2.4|497526|35|NZ_CP021983|CRISPRCasFinder	497526-497560	35	NZ_CP019585	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymA, complete sequence	489754-489788	11	0.686
NZ_CP021983_2	2.4|497526|35|NZ_CP021983|CRISPRCasFinder	497526-497560	35	NC_017327	Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence	1139253-1139287	11	0.686
NZ_CP021983_2	2.4|497526|35|NZ_CP021983|CRISPRCasFinder	497526-497560	35	NZ_CP021217	Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence	725657-725691	11	0.686
NZ_CP021983_2	2.4|497526|35|NZ_CP021983|CRISPRCasFinder	497526-497560	35	NZ_CP021794	Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence	186871-186905	11	0.686
NZ_CP021983_3	3.57|705554|34|NZ_CP021983|CRISPRCasFinder	705554-705587	34	NZ_CP028345	Vibrio parahaemolyticus isolate R13 plasmid pVpR13_55Kb, complete sequence	20304-20337	11	0.676
NZ_CP021983_3	3.57|705554|34|NZ_CP021983|CRISPRCasFinder	705554-705587	34	NZ_CP021150	Vibrio campbellii strain LA16-V1 plasmid pLA16-4, complete sequence	18278-18311	11	0.676
NZ_CP021983_3	3.57|705554|34|NZ_CP021983|CRISPRCasFinder	705554-705587	34	NZ_CP034303	Vibrio parahaemolyticus strain 20160303005-1 plasmid pVPSD2016-4, complete sequence	59553-59586	11	0.676
NZ_CP021983_3	3.57|705554|34|NZ_CP021983|CRISPRCasFinder	705554-705587	34	NZ_CP028144	Vibrio parahaemolyticus strain R14 plasmid pVpR14_56Kb, complete sequence	53847-53880	11	0.676
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NC_004041	Rhizobium etli CFN 42 plasmid p42d, complete sequence	136648-136685	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP020898	Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRetBra5b, complete sequence	104954-104991	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP021027	Rhizobium sp. TAL182 plasmid pRetTAL182c, complete sequence	157133-157170	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013633	Rhizobium sp. N324 plasmid pRspN324c, complete sequence	167316-167353	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013555	Rhizobium phaseoli strain N931 plasmid pRphaN931c, complete sequence	187012-187049	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP020950	Rhizobium sp. CIAT894 plasmid pRheCIAT894c, complete sequence	187753-187790	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013587	Rhizobium phaseoli strain N161 plasmid pRphaN161b, complete sequence	135535-135572	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013598	Rhizobium sp. N741 plasmid pRspN741c, complete sequence	173804-173841	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013561	Rhizobium phaseoli strain N841 plasmid pRphaN841d, complete sequence	167482-167519	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013578	Rhizobium phaseoli strain N671 plasmid pRphaN671d, complete sequence	192216-192253	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013550	Rhizobium phaseoli strain R611 plasmid pRetR611c, complete sequence	157198-157235	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013530	Rhizobium phaseoli strain R723 plasmid pRphaR723c, complete sequence	157198-157235	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013535	Rhizobium phaseoli strain R650 plasmid pRphaR650c, complete sequence	157198-157235	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013540	Rhizobium phaseoli strain R630 plasmid pRphaR630c, complete sequence	176728-176765	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013544	Rhizobium phaseoli strain R620 plasmid pRphaR620b, complete sequence	104068-104105	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013566	Rhizobium phaseoli strain N831 plasmid pRphaN831c, complete sequence	187013-187050	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013502	Rhizobium esperanzae strain N561 plasmid pRspN561b, complete sequence	173726-173763	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013583	Rhizobium phaseoli strain N261 plasmid pRphaN261c, complete sequence	157198-157235	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013508	Rhizobium sp. N1341 plasmid pRspN1341c, complete sequence	173804-173841	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013519	Rhizobium sp. N113 plasmid pRspN113b, complete sequence	173803-173840	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013572	Rhizobium phaseoli strain N771 plasmid pRphaN671d, complete sequence	192216-192253	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP021125	Rhizobium sp. Kim5 plasmid pRetKim5a, complete sequence	160677-160714	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013492	Rhizobium sp. N6212 plasmid pRspN6212b, complete sequence	176366-176403	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013514	Rhizobium sp. N1314 plasmid pRspN1314c, complete sequence	167482-167519	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013497	Rhizobium sp. N621 plasmid pRspN621b, complete sequence	176366-176403	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013592	Rhizobium sp. N871 plasmid pRspN871b, complete sequence	173726-173763	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	CP007643	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803b, complete sequence	216346-216383	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NC_010996	Rhizobium etli CIAT 652 plasmid pB, complete sequence	154734-154771	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP013604	Rhizobium sp. N731 plasmid pRspN731c, complete sequence	167484-167521	11	0.711
NZ_CP021983_3	3.59|705702|38|NZ_CP021983|CRISPRCasFinder	705702-705739	38	NZ_CP017243	Rhizobium etli 8C-3 plasmid pRsp8C3b, complete sequence	149809-149846	11	0.711
NZ_CP021983_3	3.69|706464|34|NZ_CP021983|CRISPRCasFinder	706464-706497	34	MN693840	Marine virus AFVG_250M262, complete genome	26840-26873	11	0.676
NZ_CP021983_3	3.69|706464|34|NZ_CP021983|CRISPRCasFinder	706464-706497	34	MN693764	Marine virus AFVG_250M260, complete genome	15162-15195	11	0.676
NZ_CP021983_3	3.69|706464|34|NZ_CP021983|CRISPRCasFinder	706464-706497	34	MN694215	Marine virus AFVG_250M156, complete genome	15405-15438	11	0.676
NZ_CP021983_3	3.69|706464|34|NZ_CP021983|CRISPRCasFinder	706464-706497	34	MN694023	Marine virus AFVG_250M259, complete genome	26502-26535	11	0.676
NZ_CP021983_3	3.69|706464|34|NZ_CP021983|CRISPRCasFinder	706464-706497	34	MN694629	Marine virus AFVG_250M263, complete genome	15160-15193	11	0.676
NZ_CP021983_3	3.69|706464|34|NZ_CP021983|CRISPRCasFinder	706464-706497	34	MN693970	Marine virus AFVG_250M261, complete genome	26767-26800	11	0.676
NZ_CP021983_14	14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR	2246065-2246101	37	NC_013859	Azospirillum sp. B510 plasmid pAB510e, complete sequence	199019-199055	11	0.703
NZ_CP021983_16	16.13|2295651|35|NZ_CP021983|CRISPRCasFinder	2295651-2295685	35	MN369754	Streptomyces phage Limpid, complete genome	36926-36960	12	0.657
NZ_CP021983_16	16.13|2295651|35|NZ_CP021983|CRISPRCasFinder	2295651-2295685	35	NC_048719	Streptomyces phage Annadreamy, complete genome	36927-36961	12	0.657
NZ_CP021983_14	14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR	2246065-2246101	37	NZ_LT703507	Mycobacterium chimaera strain Mycobacterium chimaera MC045 isolate Mycobacterium chimaera plasmid 3	77349-77385	15	0.595
NZ_CP021983_14	14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR	2246065-2246101	37	NZ_CP015273	Mycobacterium chimaera strain ZUERICH-1 plasmid unnamed 1, complete sequence	69574-69610	15	0.595
NZ_CP021983_14	14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR	2246065-2246101	37	NC_020275	Mycobacterium intracellulare subsp. yongonense 05-1390 plasmid pMyong1, complete sequence	54677-54713	15	0.595
NZ_CP021983_14	14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR	2246065-2246101	37	NZ_CP029333	Mycobacterium avium subsp. hominissuis strain MAC109 plasmid pMAC109a, complete sequence	118324-118360	15	0.595
NZ_CP021983_14	14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR	2246065-2246101	37	NZ_CP045964	Mycobacterium chimaera strain AUSMDU00007395 plasmid pAUSMDU00007395_01, complete sequence	60817-60853	15	0.595
NZ_CP021983_14	14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR	2246065-2246101	37	NC_022654	Mycobacterium kansasii ATCC 12478 plasmid pMK12478, complete sequence	61357-61393	15	0.595
NZ_CP021983_14	14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR	2246065-2246101	37	NZ_CP015280	Mycobacterium chimaera strain DSM 44623 plasmid unnamed 2, complete sequence	30752-30788	15	0.595
NZ_CP021983_14	14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR	2246065-2246101	37	NZ_CP023153	Mycobacterium chimaera strain FLAC0070 plasmid pFLAC0070_2, complete sequence	18389-18425	15	0.595
NZ_CP021983_14	14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR	2246065-2246101	37	NZ_CP019224	Mycobacterium chimaera strain CDC 2015-22-71 plasmid pDHQP20152271_1, complete sequence	61914-61950	15	0.595

1. spacer 11.1|1482385|26|NZ_CP021983|CRISPRCasFinder matches to NZ_CP026518 (Deinococcus sp. NW-56 plasmid unnamed2, complete sequence) position: , mismatch: 3, identity: 0.885

cgaaccgccgaactgcagcagaccat	CRISPR spacer
cgcaccgccgaactggagcagaccaa	Protospacer
** ************ ********* 

2. spacer 11.1|1482385|26|NZ_CP021983|CRISPRCasFinder matches to CP054927 (Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.846

cgaaccgccgaactgcagcagaccat	CRISPR spacer
ggaaccggcgaactgccgcagaccct	Protospacer
 ****** ******** ******* *

3. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024790 (Nostoc flagelliforme CCNUN1 plasmid pNFSY05, complete sequence) position: , mismatch: 5, identity: 0.853

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
ccataacaattcaaaattcaaaattcaaaattca	Protospacer
  * *******************.******.***

4. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024791 (Nostoc flagelliforme CCNUN1 plasmid pNFSY06, complete sequence) position: , mismatch: 5, identity: 0.853

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
ccataacaattcaaaattcaaaattcaaaattca	Protospacer
  * *******************.******.***

5. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 5, identity: 0.853

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
ccataacaattcaaaattcaaaattcaaaattca	Protospacer
  * *******************.******.***

6. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 5, identity: 0.853

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
ccataacaattcaaaattcaaaattcaaaattca	Protospacer
  * *******************.******.***

7. spacer 5.1|805981|31|NZ_CP021983|CRISPRCasFinder matches to NZ_AP022622 (Mycobacteroides abscessus strain JCM 30620 plasmid pJCM30620_1) position: , mismatch: 6, identity: 0.806

gctatcggtcggggcgcccaggctatcggtc	CRISPR spacer
gctgcggctcggggcgcccaggatatctgtc	Protospacer
***.. * ************** **** ***

8. spacer 5.1|805981|31|NZ_CP021983|CRISPRCasFinder matches to NC_021279 (Mycobacteroides abscessus subsp. bolletii 50594 plasmid 2, complete sequence) position: , mismatch: 6, identity: 0.806

gctatcggtcggggcgcccaggctatcggtc	CRISPR spacer
gctgcggctcggggcgcccaggatatctgtc	Protospacer
***.. * ************** **** ***

9. spacer 11.1|1482385|26|NZ_CP021983|CRISPRCasFinder matches to MN585966 (Gordonia phage Faith5x5, complete genome) position: , mismatch: 6, identity: 0.769

cgaaccgccgaactgcagcagaccat	CRISPR spacer
agaaccgccgaaccgcagcagaagcc	Protospacer
 ************.********   .

10. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024791 (Nostoc flagelliforme CCNUN1 plasmid pNFSY06, complete sequence) position: , mismatch: 6, identity: 0.824

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
ccgaaacaattcaaaattcaaaattcaaaattca	Protospacer
  ..*******************.******.***

11. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 6, identity: 0.824

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
tgttaacaattcaaaattcaaaattcaaaattca	Protospacer
 .  *******************.******.***

12. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NC_009926 (Acaryochloris marina MBIC11017 plasmid pREB1, complete sequence) position: , mismatch: 6, identity: 0.824

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
gatatctaattcaaaattcaaaactcaaaattca	Protospacer
** .  .***********************.***

13. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP050442 (Tolypothrix sp. PCC 7910 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.824

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
tcataccaattcaaaattcaaaattcaaaattca	Protospacer
  * * *****************.******.***

14. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_CP023279 (Nostoc sp. CENA543 plasmid pCENA543c, complete sequence) position: , mismatch: 6, identity: 0.833

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
actttaaggcagatggcagaaggcagaaggttttaa	Protospacer
*.** ******** **************** *  **

15. spacer 11.1|1482385|26|NZ_CP021983|CRISPRCasFinder matches to NC_023283 (Streptomyces sp. FR1 plasmid pFRL3, complete sequence) position: , mismatch: 7, identity: 0.731

cgaaccgccgaactgcagcagaccat	CRISPR spacer
gccggcgccgaactgcagcagaccta	Protospacer
   . *******************  

16. spacer 14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP018229 (Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.811

ttttcccc----caccgcctccgcctccaccccctccacct	CRISPR spacer
----gcccgaggcgccgcctccgcctccaccccctccgcct	Protospacer
     ***    *.***********************.***

17. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 7, identity: 0.794

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
ccaaatcaattcaaaattcaaaattcaaaattaa	Protospacer
  *.* *****************.******.* *

18. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 7, identity: 0.794

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
tcaaaacaattcaaaatgcaaaattcaaaatgca	Protospacer
  *.************* *****.******. **

19. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 7, identity: 0.794

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
tcaaaacaattcaaaatgcaaaattcaaaatgca	Protospacer
  *.************* *****.******. **

20. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NC_007410 (Trichormus variabilis ATCC 29413 plasmid A, complete sequence) position: , mismatch: 7, identity: 0.794

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
tcataccaattcaaaattcaaaattcaaaattaa	Protospacer
  * * *****************.******.* *

21. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP047243 (Trichormus variabilis 0441 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.794

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
tcataccaattcaaaattcaaaattcaaaattaa	Protospacer
  * * *****************.******.* *

22. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_CP011314 (Klebsiella pneumoniae subsp. pneumoniae strain 234-12 plasmid pKpn23412-362, complete sequence) position: , mismatch: 7, identity: 0.806

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
gctggaaggcagaaggcagaaggcagaaggcagaag	Protospacer
..* .*************************  ***.

23. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_LT883139 (Escherichia coli isolate 6666666.257727.embl plasmid I) position: , mismatch: 7, identity: 0.806

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
gctggaaggcagaaggcagaaggcagaaggcagaag	Protospacer
..* .*************************  ***.

24. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_CP034054 (Klebsiella pneumoniae strain KP_NORM_BLD_2015_112126 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.806

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
gctggaaggcagaaggcagaaggcagaaggcagaag	Protospacer
..* .*************************  ***.

25. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_CP034046 (Klebsiella pneumoniae strain KP_NORM_BLD_2014_104014 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.806

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
gctggaaggcagaaggcagaaggcagaaggcagaag	Protospacer
..* .*************************  ***.

26. spacer 2.1|497526|31|NZ_CP021983|CRT matches to NZ_CP021794 (Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.742

cggctgtccgaaggcattttccatgggttcg	CRISPR spacer
gatatagccgaaggccttttccatggcttcg	Protospacer
 .  *. ******** ********** ****

27. spacer 2.1|497526|31|NZ_CP021983|CRT matches to NZ_CP019585 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.742

cggctgtccgaaggcattttccatgggttcg	CRISPR spacer
gatatagccgaaggccttttccatggcttcg	Protospacer
 .  *. ******** ********** ****

28. spacer 2.1|497526|31|NZ_CP021983|CRT matches to NC_017327 (Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence) position: , mismatch: 8, identity: 0.742

cggctgtccgaaggcattttccatgggttcg	CRISPR spacer
gatatagccgaaggccttttccatggcttcg	Protospacer
 .  *. ******** ********** ****

29. spacer 2.1|497526|31|NZ_CP021983|CRT matches to NZ_CP021217 (Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.742

cggctgtccgaaggcattttccatgggttcg	CRISPR spacer
gatatagccgaaggccttttccatggcttcg	Protospacer
 .  *. ******** ********** ****

30. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024790 (Nostoc flagelliforme CCNUN1 plasmid pNFSY05, complete sequence) position: , mismatch: 8, identity: 0.765

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
ttcgggtaattcaaaattcaaaattcaaaattca	Protospacer
   *...****************.******.***

31. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024790 (Nostoc flagelliforme CCNUN1 plasmid pNFSY05, complete sequence) position: , mismatch: 8, identity: 0.765

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
aacggatcagtcaaaattcaaaattcaaaattca	Protospacer
.* *.*. * *************.******.***

32. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024791 (Nostoc flagelliforme CCNUN1 plasmid pNFSY06, complete sequence) position: , mismatch: 8, identity: 0.765

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
ttcgggtaattcaaaattcaaaattcaaaattca	Protospacer
   *...****************.******.***

33. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024791 (Nostoc flagelliforme CCNUN1 plasmid pNFSY06, complete sequence) position: , mismatch: 8, identity: 0.765

gaagaac-----aattcaaaattcaaaactcaaaactca	CRISPR spacer
-----atttttgaattcaaaattcaaaattcaaaattca	Protospacer
     *.     ****************.******.***

34. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024791 (Nostoc flagelliforme CCNUN1 plasmid pNFSY06, complete sequence) position: , mismatch: 8, identity: 0.765

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
ttaatgaaattcaaaattcaaaattcaaaattca	Protospacer
  *. . ****************.******.***

35. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024791 (Nostoc flagelliforme CCNUN1 plasmid pNFSY06, complete sequence) position: , mismatch: 8, identity: 0.765

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
ccaattcaattcaaaattcaaaattcaaaatgca	Protospacer
  *.  *****************.******. **

36. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 8, identity: 0.765

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
ttcgggtaattcaaaattcaaaattcaaaattca	Protospacer
   *...****************.******.***

37. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 8, identity: 0.765

gaagaac------aattcaaaattcaaaactcaaaactca	CRISPR spacer
------ctttttgaattcaaaattcaaaattcaaaattca	Protospacer
      *      ****************.******.***

38. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 8, identity: 0.765

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
ttaatgaaattcaaaattcaaaattcaaaattca	Protospacer
  *. . ****************.******.***

39. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 8, identity: 0.765

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
ttcgggtaattcaaaattcaaaattcaaaattca	Protospacer
   *...****************.******.***

40. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 8, identity: 0.765

gaagaac-----aattcaaaattcaaaactcaaaactca	CRISPR spacer
-----atttttgaattcaaaattcaaaattcaaaattca	Protospacer
     *.     ****************.******.***

41. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 8, identity: 0.765

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
ccaattcaattcaaaattcaaaattcaaaatgca	Protospacer
  *.  *****************.******. **

42. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NC_009926 (Acaryochloris marina MBIC11017 plasmid pREB1, complete sequence) position: , mismatch: 8, identity: 0.765

gaagaacaattcaaaattcaaaactcaaaactca-------	CRISPR spacer
-------aattcaaaattcaaaactcaaaattcaaaactct	Protospacer
       ***********************.***       

43. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_AP017296 (Nostoc sp. NIES-3756 plasmid pNOS3756_1, complete sequence) position: , mismatch: 8, identity: 0.765

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
ttgctccaattcaaaattcaaaattcaaaattca	Protospacer
  .   *****************.******.***

44. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_AP017296 (Nostoc sp. NIES-3756 plasmid pNOS3756_1, complete sequence) position: , mismatch: 8, identity: 0.765

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
tagtaacaattcaaaattcaaaattcaatatgct	Protospacer
 *. *******************.**** *. * 

45. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NC_007410 (Trichormus variabilis ATCC 29413 plasmid A, complete sequence) position: , mismatch: 8, identity: 0.765

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
atgaatcaattcaaaattcaaaattcaaaattaa	Protospacer
. ..* *****************.******.* *

46. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP047243 (Trichormus variabilis 0441 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
atgaatcaattcaaaattcaaaattcaaaattaa	Protospacer
. ..* *****************.******.* *

47. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_CP011314 (Klebsiella pneumoniae subsp. pneumoniae strain 234-12 plasmid pKpn23412-362, complete sequence) position: , mismatch: 8, identity: 0.778

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
ggcagaaggcagaaggcagaaggcagaagggagaag	Protospacer
. . .*************************. ***.

48. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to AP018321 (Nostoc sp. HK-01 plasmid plasmid3 DNA, complete genome) position: , mismatch: 8, identity: 0.778

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
gagggaaggcagaaggcagagggcagaaggaagaag	Protospacer
.   .***************.********** ***.

49. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_LT883139 (Escherichia coli isolate 6666666.257727.embl plasmid I) position: , mismatch: 8, identity: 0.778

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
ggcagaaggcagaaggcagaaggcagaaggcagaag	Protospacer
. . .*************************  ***.

50. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_LT883139 (Escherichia coli isolate 6666666.257727.embl plasmid I) position: , mismatch: 8, identity: 0.778

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
ggcagaaggcagaaggcagaaggcagaaggcagaag	Protospacer
. . .*************************  ***.

51. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_LT883139 (Escherichia coli isolate 6666666.257727.embl plasmid I) position: , mismatch: 8, identity: 0.778

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
ggcagaaggcagaaggcagaaggcagaaggcagaag	Protospacer
. . .*************************  ***.

52. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_LT883139 (Escherichia coli isolate 6666666.257727.embl plasmid I) position: , mismatch: 8, identity: 0.778

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
ggcagaaggcagaaggcagaaggcagaaggcagaag	Protospacer
. . .*************************  ***.

53. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_LT883139 (Escherichia coli isolate 6666666.257727.embl plasmid I) position: , mismatch: 8, identity: 0.778

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
ggcagaaggcagaaggcagaaggcagaaggcagaag	Protospacer
. . .*************************  ***.

54. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_LT883139 (Escherichia coli isolate 6666666.257727.embl plasmid I) position: , mismatch: 8, identity: 0.778

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
ggcagaaggcagaaggcagaaggcagaaggcagaag	Protospacer
. . .*************************  ***.

55. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_LT883139 (Escherichia coli isolate 6666666.257727.embl plasmid I) position: , mismatch: 8, identity: 0.778

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
ggcagaaggcagaaggcagaaggcagaaggcagaag	Protospacer
. . .*************************  ***.

56. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_LT883139 (Escherichia coli isolate 6666666.257727.embl plasmid I) position: , mismatch: 8, identity: 0.778

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
ggcagaaggcagaaggcagaaggcagaagggagaag	Protospacer
. . .*************************. ***.

57. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_CP034054 (Klebsiella pneumoniae strain KP_NORM_BLD_2015_112126 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.778

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
ggcagaaggcagaaggcagaaggcagaagggagaag	Protospacer
. . .*************************. ***.

58. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_CP034054 (Klebsiella pneumoniae strain KP_NORM_BLD_2015_112126 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.778

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
ggcagaaggcagaaggcagaaggcagaaggcagaag	Protospacer
. . .*************************  ***.

59. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_CP034054 (Klebsiella pneumoniae strain KP_NORM_BLD_2015_112126 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.778

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
ggcagaaggcagaaggcagaaggcagaaggcagaag	Protospacer
. . .*************************  ***.

60. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_CP034054 (Klebsiella pneumoniae strain KP_NORM_BLD_2015_112126 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.778

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
ggcagaaggcagaaggcagaaggcagaaggcagaag	Protospacer
. . .*************************  ***.

61. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_CP034054 (Klebsiella pneumoniae strain KP_NORM_BLD_2015_112126 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.778

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
ggcagaaggcagaaggcagaaggcagaaggcagaag	Protospacer
. . .*************************  ***.

62. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_CP034046 (Klebsiella pneumoniae strain KP_NORM_BLD_2014_104014 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.778

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
ggcagaaggcagaaggcagaaggcagaagggagaag	Protospacer
. . .*************************. ***.

63. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_CP034046 (Klebsiella pneumoniae strain KP_NORM_BLD_2014_104014 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.778

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
ggcagaaggcagaaggcagaaggcagaaggcagaag	Protospacer
. . .*************************  ***.

64. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_CP034046 (Klebsiella pneumoniae strain KP_NORM_BLD_2014_104014 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.778

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
ggcagaaggcagaaggcagaaggcagaaggcagaag	Protospacer
. . .*************************  ***.

65. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_CP034046 (Klebsiella pneumoniae strain KP_NORM_BLD_2014_104014 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.778

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
ggcagaaggcagaaggcagaaggcagaaggcagaag	Protospacer
. . .*************************  ***.

66. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_CP034046 (Klebsiella pneumoniae strain KP_NORM_BLD_2014_104014 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.778

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
ggcagaaggcagaaggcagaaggcagaaggcagaag	Protospacer
. . .*************************  ***.

67. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_CP024792 (Nostoc flagelliforme CCNUN1 plasmid pNFSY07, complete sequence) position: , mismatch: 8, identity: 0.778

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
aaacaaaggcagagggcagagggcagaaggaaagaa	Protospacer
*  .*********.******.********** ..**

68. spacer 3.50|705040|34|NZ_CP021983|CRISPRCasFinder matches to NC_016585 (Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence) position: , mismatch: 9, identity: 0.735

gcccaacagcagcaacaagccgcagaagccagca	CRISPR spacer
ggccaacagcagcaacaggcagcagagtgcgacg	Protospacer
* ***************.** *****.  *..*.

69. spacer 14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR matches to NC_019387 (Thermus oshimai JL-2 plasmid pTHEOS01, complete sequence) position: , mismatch: 9, identity: 0.757

ttttcccccaccgcctccgcctccaccccctccacct	CRISPR spacer
aggcccggcaccgcctccacctccaccccctccaggt	Protospacer
   .**  **********.***************  *

70. spacer 14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR594660 (Variovorax sp. PBL-H6 plasmid 2) position: , mismatch: 9, identity: 0.757

ttttcccccaccgcctccgcctccaccccctccacct	CRISPR spacer
ggtagcgccttcgcctccgccgccacccccgccacct	Protospacer
  *  * ** .********** ******** ******

71. spacer 14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR594667 (Variovorax sp. SRS16 plasmid 2) position: , mismatch: 9, identity: 0.757

ttttcccccaccgcctccgcctccaccccctccacct	CRISPR spacer
ggtagcgccttcgcctccgccgccacccccgccacct	Protospacer
  *  * ** .********** ******** ******

72. spacer 14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR594690 (Variovorax sp. WDL1 plasmid 2) position: , mismatch: 9, identity: 0.757

ttttcccccaccgcctccgcctccaccccctccacct	CRISPR spacer
ggtagcgccttcgcctccgccgccacccccgccacct	Protospacer
  *  * ** .********** ******** ******

73. spacer 14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR594672 (Variovorax sp. PBL-E5 plasmid 2) position: , mismatch: 9, identity: 0.757

ttttcccccaccgcctccgcctccaccccctccacct	CRISPR spacer
ggtagcgccttcgcctccgccgccacccccgccacct	Protospacer
  *  * ** .********** ******** ******

74. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 9, identity: 0.735

gaagaacaattcaaaattcaaaactcaaaactca-------	CRISPR spacer
-------aattcaaaattcaaaattcaaaattcaaaattca	Protospacer
       ****************.******.***       

75. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to NZ_CP024788 (Nostoc flagelliforme CCNUN1 plasmid pNFSY03, complete sequence) position: , mismatch: 9, identity: 0.735

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
tttattgaattcaaaattcaaaattcaaaattca	Protospacer
   .   ****************.******.***

76. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to AP018320 (Nostoc sp. HK-01 plasmid plasmid2 DNA, complete genome) position: , mismatch: 9, identity: 0.735

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
tcttgtcaattcaaaattcaaaattcaaaatgca	Protospacer
    . *****************.******. **

77. spacer 14.28|2247275|34|NZ_CP021983|CRT matches to JQ062992 (Bacillus phage phIS3501, complete genome) position: , mismatch: 9, identity: 0.735

gaagaacaattcaaaattcaaaactcaaaactca	CRISPR spacer
aatgaacaattaaaaattcaaaacgcactagacc	Protospacer
.* ******** ************ **  *  * 

78. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NC_010631 (Nostoc punctiforme PCC 73102 plasmid pNPUN01, complete sequence) position: , mismatch: 9, identity: 0.75

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
ctagaaaggcagagggcagaaggcaggaggcaggag	Protospacer
 *  *********.************.***  *.*.

79. spacer 3.49|704969|35|NZ_CP021983|CRISPRCasFinder matches to MN234235 (Mycobacterium phage BogosyJay, complete genome) position: , mismatch: 10, identity: 0.714

gcgcgatcagttcctcgcggaggttgctagcgata	CRISPR spacer
cgtcgatcccttcctcgcggaggttgctgaccagg	Protospacer
   *****  ******************..* * .

80. spacer 3.49|704969|35|NZ_CP021983|CRISPRCasFinder matches to MN234200 (Mycobacterium phage Maminiaina, complete genome) position: , mismatch: 10, identity: 0.714

gcgcgatcagttcctcgcggaggttgctagcgata	CRISPR spacer
cgtcgatcccttcctcgcggaggttgctgaccagg	Protospacer
   *****  ******************..* * .

81. spacer 3.55|705408|35|NZ_CP021983|CRISPRCasFinder matches to KC847113 (Bacillus phage PBP180, complete sequence) position: , mismatch: 10, identity: 0.714

-----ctagggattttcgctgctttttcgctgccttctga	CRISPR spacer
acatcctgaa-----tcgctgctttttctctgcctgctga	Protospacer
     **...     ************* ****** ****

82. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 10, identity: 0.722

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
cgggaaaggcagagggcaggaggcagaaggctttta	Protospacer
    *********.*****.********** *   *

83. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 10, identity: 0.722

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
caagaaaggcagagggcagaaggcaggaggctcagt	Protospacer
    *********.************.*** * *. 

84. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_CP023279 (Nostoc sp. CENA543 plasmid pCENA543c, complete sequence) position: , mismatch: 10, identity: 0.722

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
gaggcaaggcagacggcagacggcagaaggaaggag	Protospacer
.    ******** ****** ********** *.*.

85. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_CP024790 (Nostoc flagelliforme CCNUN1 plasmid pNFSY05, complete sequence) position: , mismatch: 10, identity: 0.722

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
ggcagaaggcagagggcaggaggcagaaggaaaaat	Protospacer
. . .********.*****.*********** .** 

86. spacer 25.1|4121072|36|NZ_CP021983|CRISPRCasFinder matches to NZ_AP014816 (Geminocystis sp. NIES-3708 plasmid pGM01, complete sequence) position: , mismatch: 10, identity: 0.722

atttaaaggcagaaggcagaaggcagaaggatgaaa	CRISPR spacer
gaaaaaaggcagacggcagaaagcagaagggaaata	Protospacer
.   ********* *******.********. .* *

87. spacer 2.4|497526|35|NZ_CP021983|CRISPRCasFinder matches to NZ_CP019585 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymA, complete sequence) position: , mismatch: 11, identity: 0.686

cggctgtccgaaggcattttccatgggttcggaaa	CRISPR spacer
gatatagccgaaggccttttccatggcttcgggtg	Protospacer
 .  *. ******** ********** *****. .

88. spacer 2.4|497526|35|NZ_CP021983|CRISPRCasFinder matches to NC_017327 (Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence) position: , mismatch: 11, identity: 0.686

cggctgtccgaaggcattttccatgggttcggaaa	CRISPR spacer
gatatagccgaaggccttttccatggcttcgggtg	Protospacer
 .  *. ******** ********** *****. .

89. spacer 2.4|497526|35|NZ_CP021983|CRISPRCasFinder matches to NZ_CP021217 (Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence) position: , mismatch: 11, identity: 0.686

cggctgtccgaaggcattttccatgggttcggaaa	CRISPR spacer
gatatagccgaaggccttttccatggcttcgggtg	Protospacer
 .  *. ******** ********** *****. .

90. spacer 2.4|497526|35|NZ_CP021983|CRISPRCasFinder matches to NZ_CP021794 (Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence) position: , mismatch: 11, identity: 0.686

cggctgtccgaaggcattttccatgggttcggaaa	CRISPR spacer
gatatagccgaaggccttttccatggcttcgggtg	Protospacer
 .  *. ******** ********** *****. .

91. spacer 3.57|705554|34|NZ_CP021983|CRISPRCasFinder matches to NZ_CP028345 (Vibrio parahaemolyticus isolate R13 plasmid pVpR13_55Kb, complete sequence) position: , mismatch: 11, identity: 0.676

taaatatcgggggctgcccgttgttcctcctcaa	CRISPR spacer
caaatctcgggggctgcccgtttttatctcattg	Protospacer
.**** **************** ** ...* . .

92. spacer 3.57|705554|34|NZ_CP021983|CRISPRCasFinder matches to NZ_CP021150 (Vibrio campbellii strain LA16-V1 plasmid pLA16-4, complete sequence) position: , mismatch: 11, identity: 0.676

taaatatcgggggctgcccgttgttcctcctcaa	CRISPR spacer
caaatctcgggggctgcccgtttttatctcattg	Protospacer
.**** **************** ** ...* . .

93. spacer 3.57|705554|34|NZ_CP021983|CRISPRCasFinder matches to NZ_CP034303 (Vibrio parahaemolyticus strain 20160303005-1 plasmid pVPSD2016-4, complete sequence) position: , mismatch: 11, identity: 0.676

taaatatcgggggctgcccgttgttcctcctcaa	CRISPR spacer
caaatctcgggggctgcccgtttttatctcattg	Protospacer
.**** **************** ** ...* . .

94. spacer 3.57|705554|34|NZ_CP021983|CRISPRCasFinder matches to NZ_CP028144 (Vibrio parahaemolyticus strain R14 plasmid pVpR14_56Kb, complete sequence) position: , mismatch: 11, identity: 0.676

taaatatcgggggctgcccgttgttcctcctcaa	CRISPR spacer
caaatctcgggggctgcccgtttttatctcattg	Protospacer
.**** **************** ** ...* . .

95. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NC_004041 (Rhizobium etli CFN 42 plasmid p42d, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

96. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP020898 (Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRetBra5b, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

97. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP021027 (Rhizobium sp. TAL182 plasmid pRetTAL182c, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

98. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013633 (Rhizobium sp. N324 plasmid pRspN324c, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

99. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013555 (Rhizobium phaseoli strain N931 plasmid pRphaN931c, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

100. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP020950 (Rhizobium sp. CIAT894 plasmid pRheCIAT894c, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

101. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013587 (Rhizobium phaseoli strain N161 plasmid pRphaN161b, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

102. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013598 (Rhizobium sp. N741 plasmid pRspN741c, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

103. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013561 (Rhizobium phaseoli strain N841 plasmid pRphaN841d, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

104. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013578 (Rhizobium phaseoli strain N671 plasmid pRphaN671d, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

105. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013550 (Rhizobium phaseoli strain R611 plasmid pRetR611c, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

106. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013530 (Rhizobium phaseoli strain R723 plasmid pRphaR723c, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

107. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013535 (Rhizobium phaseoli strain R650 plasmid pRphaR650c, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

108. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013540 (Rhizobium phaseoli strain R630 plasmid pRphaR630c, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

109. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013544 (Rhizobium phaseoli strain R620 plasmid pRphaR620b, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

110. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013566 (Rhizobium phaseoli strain N831 plasmid pRphaN831c, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

111. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013502 (Rhizobium esperanzae strain N561 plasmid pRspN561b, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

112. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013583 (Rhizobium phaseoli strain N261 plasmid pRphaN261c, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

113. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013508 (Rhizobium sp. N1341 plasmid pRspN1341c, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

114. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013519 (Rhizobium sp. N113 plasmid pRspN113b, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

115. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013572 (Rhizobium phaseoli strain N771 plasmid pRphaN671d, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

116. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP021125 (Rhizobium sp. Kim5 plasmid pRetKim5a, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

117. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013492 (Rhizobium sp. N6212 plasmid pRspN6212b, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

118. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013514 (Rhizobium sp. N1314 plasmid pRspN1314c, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

119. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013497 (Rhizobium sp. N621 plasmid pRspN621b, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

120. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013592 (Rhizobium sp. N871 plasmid pRspN871b, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

121. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to CP007643 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803b, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

122. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NC_010996 (Rhizobium etli CIAT 652 plasmid pB, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

123. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP013604 (Rhizobium sp. N731 plasmid pRspN731c, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

124. spacer 3.59|705702|38|NZ_CP021983|CRISPRCasFinder matches to NZ_CP017243 (Rhizobium etli 8C-3 plasmid pRsp8C3b, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgatcgaggcgatcgaggcgggagatgccaatgagg	CRISPR spacer
ggcgatcgaggcgatcgaagcgggcgagatggttatcg	Protospacer
******************.***** ** .. . *.  *

125. spacer 3.69|706464|34|NZ_CP021983|CRISPRCasFinder matches to MN693840 (Marine virus AFVG_250M262, complete genome) position: , mismatch: 11, identity: 0.676

tcagacaggcgagaccacaattgacaagtacgca	CRISPR spacer
cacgacaggtgagaccacgattgacaatattgat	Protospacer
.  ******.********.********   .*  

126. spacer 3.69|706464|34|NZ_CP021983|CRISPRCasFinder matches to MN693764 (Marine virus AFVG_250M260, complete genome) position: , mismatch: 11, identity: 0.676

tcagacaggcgagaccacaattgacaagtacgca	CRISPR spacer
cacgacaggtgagaccacgattgacaatattgat	Protospacer
.  ******.********.********   .*  

127. spacer 3.69|706464|34|NZ_CP021983|CRISPRCasFinder matches to MN694215 (Marine virus AFVG_250M156, complete genome) position: , mismatch: 11, identity: 0.676

tcagacaggcgagaccacaattgacaagtacgca	CRISPR spacer
cacgacaggtgagaccacgattgacaatattgat	Protospacer
.  ******.********.********   .*  

128. spacer 3.69|706464|34|NZ_CP021983|CRISPRCasFinder matches to MN694023 (Marine virus AFVG_250M259, complete genome) position: , mismatch: 11, identity: 0.676

tcagacaggcgagaccacaattgacaagtacgca	CRISPR spacer
cacgacaggtgagaccacgattgacaatattgat	Protospacer
.  ******.********.********   .*  

129. spacer 3.69|706464|34|NZ_CP021983|CRISPRCasFinder matches to MN694629 (Marine virus AFVG_250M263, complete genome) position: , mismatch: 11, identity: 0.676

tcagacaggcgagaccacaattgacaagtacgca	CRISPR spacer
cacgacaggtgagaccacgattgacaatattgat	Protospacer
.  ******.********.********   .*  

130. spacer 3.69|706464|34|NZ_CP021983|CRISPRCasFinder matches to MN693970 (Marine virus AFVG_250M261, complete genome) position: , mismatch: 11, identity: 0.676

tcagacaggcgagaccacaattgacaagtacgca	CRISPR spacer
cacgacaggtgagaccacgattgacaatattgat	Protospacer
.  ******.********.********   .*  

131. spacer 14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR matches to NC_013859 (Azospirillum sp. B510 plasmid pAB510e, complete sequence) position: , mismatch: 11, identity: 0.703

ttttcccccaccgcctccgcctccaccccctccacct	CRISPR spacer
ctgacccccatcgcctccgcctccgcccccatggcgc	Protospacer
.*  ******.*************.***** . .* .

132. spacer 16.13|2295651|35|NZ_CP021983|CRISPRCasFinder matches to MN369754 (Streptomyces phage Limpid, complete genome) position: , mismatch: 12, identity: 0.657

cactcatcaataatttcaatgagtatgattttagg	CRISPR spacer
ataatgcgaataatttcattgattatgattttatc	Protospacer
    ... ********** *** **********  

133. spacer 16.13|2295651|35|NZ_CP021983|CRISPRCasFinder matches to NC_048719 (Streptomyces phage Annadreamy, complete genome) position: , mismatch: 12, identity: 0.657

cactcatcaataatttcaatgagtatgattttagg	CRISPR spacer
ataatgcgaataatttcattgattatgattttatc	Protospacer
    ... ********** *** **********  

134. spacer 14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LT703507 (Mycobacterium chimaera strain Mycobacterium chimaera MC045 isolate Mycobacterium chimaera plasmid 3) position: , mismatch: 15, identity: 0.595

ttttcccccaccgcctccgcctccaccccctccacct------	CRISPR spacer
------gctgccgcccccgcctccgcctccacccccagacggg	Protospacer
       *..*****.********.**.** ** **       

135. spacer 14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015273 (Mycobacterium chimaera strain ZUERICH-1 plasmid unnamed 1, complete sequence) position: , mismatch: 15, identity: 0.595

ttttcccccaccgcctccgcctccaccccctccacct------	CRISPR spacer
------gctgccgcccccgcctccgcctccacccccagacggg	Protospacer
       *..*****.********.**.** ** **       

136. spacer 14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR matches to NC_020275 (Mycobacterium intracellulare subsp. yongonense 05-1390 plasmid pMyong1, complete sequence) position: , mismatch: 15, identity: 0.595

ttttcccccaccgcctccgcctccaccccctccacct------	CRISPR spacer
------gctgccgcccccgcctccgcctccacccccagacggg	Protospacer
       *..*****.********.**.** ** **       

137. spacer 14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029333 (Mycobacterium avium subsp. hominissuis strain MAC109 plasmid pMAC109a, complete sequence) position: , mismatch: 15, identity: 0.595

ttttcccccaccgcctccgcctccaccccctccacct------	CRISPR spacer
------gctgccgcccccgcctccgcctccacccccagacggg	Protospacer
       *..*****.********.**.** ** **       

138. spacer 14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045964 (Mycobacterium chimaera strain AUSMDU00007395 plasmid pAUSMDU00007395_01, complete sequence) position: , mismatch: 15, identity: 0.595

ttttcccccaccgcctccgcctccaccccctccacct------	CRISPR spacer
------gctgccgcccccgcctccgcctccacccccagacggg	Protospacer
       *..*****.********.**.** ** **       

139. spacer 14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR matches to NC_022654 (Mycobacterium kansasii ATCC 12478 plasmid pMK12478, complete sequence) position: , mismatch: 15, identity: 0.595

ttttcccccaccgcctccgcctccaccccctccacct------	CRISPR spacer
------gctgccgcccccgcctccgcctccacccccagacggg	Protospacer
       *..*****.********.**.** ** **       

140. spacer 14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015280 (Mycobacterium chimaera strain DSM 44623 plasmid unnamed 2, complete sequence) position: , mismatch: 15, identity: 0.595

ttttcccccaccgcctccgcctccaccccctccacct------	CRISPR spacer
------gctgccgcccccgcctccgcctccacccccagacggg	Protospacer
       *..*****.********.**.** ** **       

141. spacer 14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023153 (Mycobacterium chimaera strain FLAC0070 plasmid pFLAC0070_2, complete sequence) position: , mismatch: 15, identity: 0.595

ttttcccccaccgcctccgcctccaccccctccacct------	CRISPR spacer
------gctgccgcccccgcctccgcctccacccccagacggg	Protospacer
       *..*****.********.**.** ** **       

142. spacer 14.11|2246065|37|NZ_CP021983|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019224 (Mycobacterium chimaera strain CDC 2015-22-71 plasmid pDHQP20152271_1, complete sequence) position: , mismatch: 15, identity: 0.595

ttttcccccaccgcctccgcctccaccccctccacct------	CRISPR spacer
------gctgccgcccccgcctccgcctccacccccagacggg	Protospacer
       *..*****.********.**.** ** **       

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	302064 : 372910	59	Lactobacillus_phage(16.67%)	protease,integrase,transposase	attL 328503:328518|attR 359987:360002
DBSCAN-SWA_2	782611 : 838302	43	Cafeteria_roenbergensis_virus(100.0%)	protease,tail,transposase	NA
DBSCAN-SWA_3	4789098 : 4799086	7	uncultured_Mediterranean_phage(16.67%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP021983|302064:372910|DBSCAN-SWA
GCTATGGCAGGCGGCGATGACAGCCACGGTAAAACCCGTAGGCCAAGCTGCCTAGCAGGGCTAGCCCCAGTAACCCTGCCAGAGGATTTTGCCCAATGCCGGTTAACCAAGGGGAAATGTGGGCTGCTGGCCTGACCATATCGGTCACATCAACCACGTAATAGGCTCCCACTAAGCCGCCATGCAAGCCGATGGGTAGGGCCAAGCTCGGGGAGCGGTGGCCTAAGCGGGTGCGGCGGGCCCAGACAAGGGTAAGCCCTAGTAGGAGTAATCCAACAAATTGAGGCAGGCTGTCGAGAATAGCCGCCAGGGGTCTGAGGTAATGTGCGATCGCAAATAGTCCGGCATCACCCCAAAGGGCGACCGCCATAGAATAATCCTGCTCCAGCTCAAACAACAGCCAGCCCCGGAAAAACAGCTCCTCGGCCATCCCCACCCCTAACCCAACCAAGCACCCCTGCCAGACATAGTGCCCCATTGCCAGTGGCAGCGGTTGTAAGGTTCCCCAGCCTAACCCAATCTGCAGCCCTAATAGCGCACCAACACTGAGGTACCCCAGGGCCAATCCTACCCCCAGACCAGCCACCATCTTGCCAGGATGATGCAGCCCCAAGGTGCGATAGGGTTGGCTGAGGTCATGGATGCGCCGTCCCCACCCAGGCAGTAAGCCCAAAAACACAATATACAGAAGCCCTAAAGCCAATGGCCCTGCTGCCGTCCACCGCTCCTCAACACCATATAACGGCAGTCCCAGCGGTAACCAGGCCGCCCCTAAGACCATCAGGAACAGGCCAATCCGAAGCGGTGCTGGCCAGCAGCCCATAGCCCTAAGCAGTTTCAACCATCCTCTGCCCCTAATTCCTACTCATCGGGCTCGATGGAGCTAGTCAATCCCCGCCCCCGTAAGCCTTCACAATAAAACTCGGCATGCTCCAGGGCGCAGGTAATCACCAGAGCCACCTCCGCCGTATGGGCCTGCATCATAATATCGACCGCCTGGGGCATGGTTAGGCTAGGGACTACCTTCATCAACGACTCCACCACATGCTCCATTGTGTTGAAGTCATCGTTGTGGAGCAGCACCCGGTAGCGGGGAGCAGGTTTGCGAATTGTCGATGTTGAGGAGCGTTCAATGGTCTCAACCGACACGGGGTCCCCCTATGTTCACTAAGGTATGGACTTAAAGACGCTAATAGGGCCTAAAGCGACCTTTTCTACGTTGTATCACACTGCTTTATCCACGGGGAGCAGCGAGATGGGCAGAACCCTCGTGGACATCGTCTGGGCAGCATTCCCTAGAGGGCTTAGCTGGCCAACGATACAATAGGGCTGCTTACCTACATCACGAGTCGCGCGTCCGTCTCTAGGCCATGGCCTTTCGACCTAACCAAATTCTTTATCTAGAACACAATGGCCGGCGTCTCTATGTGGAGGTCATTCAGATTATCGAGTCACGCCAAATCTGCTGGGCTAGGCCACTGCTACTGGTCGATGTCTCAGATAGCCAGGAGATGCCAGACGACATCTCCCCTGAGCATGGGCTCCATTGCTTACAGGGTGGTCCCGACATTCTCTGGCCCCTGGCCCAATTTCAACCTGCCCTAGATACTGCCCTGCTGCCGCTGCTGGGTTACCTGACTCCCTCTGGCGCCTTCCCAACATCGGCCTCTTTTTCCGAGCGTCGCCTCCATCAACCCCTGCGCCAATTTATGGATGCCCTCTGGATGGATCAGCAACAGCAGTTCTTCGGGCAGGGTGCCTAAGGAAAACTCGAGGAAAACTCAGGCACTTACCCATAAACACGGAGAGCCCTACCGCGAAAACCGAGAAAAATCTTTACAAATTCGCTAAATCACTTCAGAATCCTTCAATATCTATTACAGTGCCCTTAAAGCCCTTGACGCCTATGGCCTATGGTCCTTTCAGCCTTGGGTTCAGCCTTGGGTAAAGTCCCACTAAGGGCTTGGCACCAACTTAACCCGCCCAGCATCCATCTCACACATGAGCAATTCCAAGGCCTCGAAATCCACTTCCGAGACATAGCCAAGGCGACTCAGTTCGCAGTTGATGCCCTGCTCGATATCAGGGGTCAAGCGACGAATGTACAGTGCTCTTTCAACGAGGGTTCGAATGATAGTCGATGATGCCTGCATACCAAGAGCCAGCCAAGCTGGTTAGTGTGTAAGGTGCTAGTTATGATTCTCTGATACCGACTCCATCCAGAGCGTGATCCAGCCATAAGCTCTTGCGTGATTAGCGTCAAACACTGTGGTGATTTAGATCACATTTGCTCTAGTAGTAACGCAGGGCACTGTACGTGATATCACTTACCTGAAACTTTAAACAAATCAGAATGGTCATTAAGATTCAGCGAAACAAACGCCTCGGTCTGGGCATCCCCAGCTGAGCAGCTTAACGTCAATGTCATCGGACGGGTTTGAGTACGGCGACCTCTGTTGTCAGACTTCGCAGGAGTGAATGGGTATGTACAGCTTCGATACTTCTATGATGTTTATGCAGCCTAGCGGTGCTCTCAGTGCCGCCAATGCCCAAGATTTTTATGGTCAGATGGCTAGCCAGCTACGGTCCGATCCGGTAACTGGCTTAGTTGTGGACATGAGCCAGGTGGAATCTTTAGACAGTGCTGGCTTAAATGCCTTAGCCTCTGCCTTGCAGCTAGCACAAACTCTGAACAAGACGTTTCGCCTCAAGGCAGTTCCTCCTTCCATTCAGATTATTTTTGAGCTGACTCAGTTGGATGGGGTGTTTGAGCTAGCTGATGACTCGGCAGTGCTGCCTGTGGCTGCTTAACGTTGATATGGTGCAGCCCCAGTGGCACGAAATACCTTAGACGTGCTGGCGATTGTTCATCGCCGCTATGCCGTCTCTGGAATACCTGGCAATACTCTCGGAAATGCTCTCGGAGCAAATGATTCGGGAGTATTTTACTGGCTCTGTTAAGCCGCCAAGGCCCCCGCAGCTATCCGCTATAGTGAAGGCAATGTCGCAAGCATAGTGTGGTTAGTTGTCGTGCCCGTTGCTATCGAATCCCTGATCAATGCGGATGTTGCCAAACCAGCCCGATATTTAGGCAATGAGCTGGGGGCTGTCCATAAACCCTGGCATCAGGCTCAGGTGCGATGGGCCCTCACCTACCCAGAACTCTACGAGGTGGGCGCCTCTAATCTGGGGCATATCATCCTGTACAGCATTCTCAATGCTCAACCTCGGCAACTGTGCGATCGCGCCTATTTGCCTGCTGCCGATTTAGTGACTAAGCTGCGGCAAAGCGGGACGCCTCTGTTTGCCGTCGAGTCCCGTCGCCATCTGCTCGAGTTCGACATTCTCGGTTTCAGCCTCAGCTACGAACTAGGGGCCACCAATCTGCTAGAAATGCTAGATCTGGCTCAGATTCCGTTGACCTGGCGAGAGCGACAGCAGGCGGGTCCCTGGGCCGTAGACAGCGGCAGTTGGCCCCTGATCTTTGCTGGGGGGCAAACGGCTACTTCCAATCCTGAACCCTACGCCGATTTCCTGGACTTCGTTGCCCTCGGGGATGGGGAGGAATTACTGCCTGAGATTGCCCTAGTGGTAGAAGAAGGCAAAGCCGCCGGGCTCAGTCGTCAAGACCTACTGCTCGATCTAGCTCAGGTGCCAGGGGTGTACGTACCCCAGTTCTATGACATGGCCGCCGATGGTTCCGTGTATCCCAACCGCCCTGATGTCCCGGCTCGGGTCGTGCGTCGGGTGGCAACACCGATGCCAGAGTATTCCATCGGCTTAGTGCCCTATGTCGAAACTGTCCATGACCGCCTCACGGTGGAAATTCGCCGTGGCTGCACCCGCGGCTGCCGCTTCTGCCAGCCCGGCATGCTAACCCGTCCCGCCCGGGATGTGTCGCCAGACAAAGTGGTAGACACCATTGAGCAGGGTCTTCGAAAAACTGGCTACAACGAGTTCTCCTTGCTCTCCCTGAGTTGCTCCGATTATCTGGCCCTACCTTCCCTAGGTGTAGAGGTGAAAAATCGGCTGCAACAGGAGAATATTTCCCTGTCCTTGCCCAGCCAGCGGGTTGACCGCTTCGATGAAAATATCGCTCACATTATCGGCGGTACTCGTCAAACCGGGCTGACATTTGCCCCGGAGGCTGGTACCCAGCGGATGCGAGACATTGTCAATAAGGGCCTAACCAACGAAGAGCTACTCCGGGGTGTCAAAACCGCCTATGAGCAGGGATGGGATCGGGTGAAGCTCTACTTCATGATTGGTCTGCCGGGTGAGACCGATGTGGATGTCTTGGGGATTGCCGAGACCGTACGGTGGCTGCGGCAAGAATGTCGCCAGCCAGGACGCAAGGCTCTGGCGGTGAACCTGACCATTTCGAACTTCACCCCCAAACCCCATACCCCCTTCCAGTGGCATGCCGTGTCTACCGCCGAGTTTGAACGGAAGCAAGCCCTGCTTAAAGAAGAGTTTCGCTCCCTACGAGGGGTCAAGATGAATTTCACGGATGTGCGCATCTCGGCCATGGAAGACTTTGTCGGTCGCGGAGATCGTCGTCTAGCCGCTGTAGTGCATCGGGCCTGGCAACTGGGGGCGGGTATGGATGCCTGGTGGGAAAGTCTAGATCGGGCCTTTGCCGCTTGGACCCAAGCCATTGACGAGGCGGGGCTGAGCTGGAAGTATCGGCAGCGAGAGCAGGACTGGAACACGCTGGAGGCAGGCGAGCAGGCTGCAAGCCTGGAGGCTCCCTTGCCCTGGGACCACATCGATACCGGCATCGATAAAGCGTGGCTGCAGGCCGATCTGCGCCGGGCCTTGGCGGCCGCCACTGTGCCCGATTGTTCCTTTGAGGGCTGCTCCCACTGTGGGGTCTGTGGCCCCGACTTCGGCCACAACGTGGTGGTGGCGCCACCGCCAATTCCCACCTTTGAGGGACACTTTACCCCGCCCCAAGAGCGGGTGCAGCGGATTCGGGTGCGCCTGGGTAAGCAGGGCAATCTCACCTTGCTCAGCCATTTGGATTTGATGCGGTTGCTGGATCGAGCCGTACGCCGGGCTGCCTTACCTCTGGCCTTTACGGGAGGGTTTCATCCGGGCCCGCGAATTTCTGCGGCCAATGCCTTACCCCTGGGGGCCACTAGTGCCGGTGAAATCGTCGATTTTGAGCTGACCTCTCCCTTAGCGGTCGCAGCCTTTTGCCAGCGGCTAGGGGCAGAACTGCCCTCGGAGCTCCCTATTCATGAGGCTGCGGAAGTATCTTTGTCGGCGCCGTCGGCGACCAAGGCCTTGGCGCAGGCTGAGTATGTGATCACGGTGGCAGGGGCCGACGAGGTTGCGATCGCACCAGCAGAGTGGGCGGCCTGGGTCGCTGCCGTCAAGGCGGCCGATAGGATAATCTGGGACCATCGGACTAAGTCGGGCAAGTTGCGGCAGGTCAATCTGTGCGATCGCCTCGATAGCCTTGACCCGATAGCGGCTCCGTCTCCTCAGGACCTGCCACCCCAGAGCCACCTCAGCGATCCAGCCCATCAGGCCCTGATTCGCTATGGGGGCAGTTGTCGCAATGACGGCAGCCAACTGCGCCCCGACCATGTGGTCTTCATGCTAGAGCAGGTGAGCCAACGGCCCCTACGGCTCTGTCACATCCATCGTCAACGGCTTATCCTTACTCCTACGCCGGGAGATTCTACCCATGCAGCTGAAATGGTTACGGCCTCGGTTACGGCTTCTTTGGGGACCCATTAATCCTGGAGTGAGGGTGCTGGCGGCTGCGGGCCTGCTCCTAGGACTAGGGATACCGGCCTGGAGTCAGACGTCATCCCCCGGGGCCAGTACCTGCCAGGTAGATATCCTGGGCTCGGAGTTGGCATGGCGGCAATGTTGGCTGGAAGCCACTCCCCTGTTATCCACAGAAAGCGACGCCACCATCGTCGACGAAGACACCCTATCCCTAACGACAATGACCCGGCCCAGCCTCTGGTGGCGTCGAGATCAGCTGCCCTCTCGCTTAGGCGGAGATCGCCTGATCGAGGGCTGGACAGCCTATCACTTGGTCGACCCGACCATGCAGGTCATCGATATTGACATCAATGGACAGGGCTGGCGGATCCTCACCCTGGCGGAGCGTTATGGCTTGCTGACCCAGTTTGGCTCAGCGGCTAAAGCCTACGGCTATAACGTGCGGTTATATCGGGGCAGCGATCAGTTTCGAGAGCGATTGGCGCTGTATGTGTGCGATTTTAGTCACACTCCGGAGCTAGAGGGGCAGACAAGCACAGACTCAGACGCTACGGCCCAAATCCCCTGCAACGCTGAATTGTATGACCCTGGCCAACTCTAACCAGGGCTGCGCATCTCTTGCCAGAGCCGATCGTAGGCAGTTTGCGCCGAGTCCGATAGGGGCTGCAGAAACTCACTGCGGCCATAGAGGTCTGCTGGTGGAAAGATCAACGGCTGCTCCTGTAGATTAGAAGGCAATGCCTGGCGTTGCTGCCCAGCGTAGAGCGGAGACCCTCCCTGACTCAGGAGCGATAGCTGCGCGGCATGGTCAGGCGTGAGGCAAAATTCGATCCACTGTTTTGCTGCCGCAGACAAGGGCAATGGCGCATTGGTGGGACGCACCCACAGATCTGCCGTCAGTATTGTTCCTTCCTGGGGGATTCCGGCTTGAAATTGGCGATATTGGCTCAACTGGGGCAGCAAATCGGTGGACCAGCCCACGATCAACCAGAGATCGCCATTGATTAGGGCTTTCAACCCATGCTCGGAGCTGTATAGCTGCACCTGTTGTTGCAGGGTCTGTAGTCGCTCCGATAGTGCGGCCATGGCCTGCACATCAGGAGAATTGGCCGATTGATTCAGGGCCTTCAGGGCCAGCCCCAACACCAACCGCGGATGATCCGGCAAGGCAAAACGACGCTGTAGATCTGGGTGCCACAGATCTTGCCATTGGCTAGGCTGCCAGCCTAACCGCTGAAATGGCCGGGGGTCGTAGATCCAAATCAAGCTGCCCCATCGGTAAGGGACGGCCCAGATCGCTCCGTCCTCTGCGAATTGACCGTTGCGATCGCGTCGCACCAACTGCTGCCAAGCAGGAGATAGCCGTTGCCAGCCGGGTAAATGCTCTGAGCGCAGTGGTTGAATCAACTGCTCTTGGACTGCCGCCGTCAGCCAATAATCACCTAAGCTGACCCAATCAGGGGCATTCCCTGGGGATGACTCTGATTGCCAGAACCGCACCCAATTCCAAATCCGTTGCCACCGGGGAACCGCCTCTCCAGGGAGCCTCTGCCACCGGCGTAAATCCTGGAATAGCGATAACAGAGAAGGGGTGGCCGTAAACGTAGCCGACGCTTGGCTCTGCCGTTTAAATCGTTTGATCAGTCGGGCCGGGATTGACCCCTCCAACAGCCTCACCTCAACCTCAGGGGAGGCGGGGCCACAGGCCGAGAGTCCTAGGCCAATAGTTGCCGCCACTAACTGCAAAAACGTTCTACGCTTCATCGTTGGGATGCTCACCGTTATTGCCCACTATTAAACCGATATCACAGCCACAGACATTCCTGTCCGTGGCACTCTACTGTATCGTTCGAAACAATTAGTCCTCTTCAGACTGTGAAAGGTTAAATGTTGATTGAGCTATTCAGGGATGTCCGAATCTAGAGCCTAGGATAGGAAGGAACTCATGTGAGATGAAATGTCCTATGGACTCTCTTCAGGAACAGGTTACAGTTTTGACCACCAAGGTAGATGCTTTGCATACCGCCCTGGATCAGGTCAATCATCGGGTCTCTGAAATCCTAAATACCTCCCAACCAACCCTGAACGATGGGTTCACTGATTCGGTGATGGGAAACGATGGTCAATCCACTGTGATTGCCGAGGGGATGTTTGAGCACAAAGATATTCTGATGGATACCACCTACTCAAAGCTGGACCACTCCAGTACAGAAACTCAGATCTCTCCAGAAGTACAGGTGCGAAGACTAACGGCTCAGTTAACTGCCGCCTATAATCGCATTGCGGCCCTAGAAGAGCAGTTGCTGGCGCTACGCAGTCACCATTGAGTAGTTCCCTTCCCGGGGTGATTTTCGTCGACAGTATCCATGACGGGACACCTCCCCTTCATCTCAATCAATTTGTCCCTGTCCCGACATGCCATTGATTCGAAGCGTTTGTTCCCACAGGGCTTCCACGGCAGCCAAAAGCTCTGGCTGCTGCCAGTTTTTGTGGAGATGGGCTGCGATCGCACATCCGCCAGCCCCCACCCCTTCCTTCACAAATCCCTGCTCATAGGCTCGCAGTTGCGGATAATGAGACCTCTCAAAGCTCAACTGAGTGGCGATTAGCGGCACATCTGCTACCTGCACAGCAAGGCCAACCGTGTCTCCACTACCATCTGTGGCCACCCAACGGGTCGTTCCCACGGCAATGCGCTCCGGGGTCCAAGCTAGGCCATGGTAGCCTGCCACTGCCCGCAGCAGCGCGTAGACAGCCAACATTTGGGTCCCCCCCGCCAGCAACACCCCAACCCGTCGACTTGCCGCAATTGCCATCGCCGCCACCACCACCTGCATCGGGTCACCTACCGCCGCCGCCAGTGCCAATGGATCTAGGGCCCCCTCCGTAAAGGCAGGGGATTGCCGCCAGGCAGACAGTCCGGCTTGGGCAACTGCTAACTTCTGTGTATGGTTACAGGTGGGATGGCTGCTGTTGACCCGGTCCGTGGCGTCGATCCCTAACCCCAGTAGCACGGCCAAGGCCGTTGTGGTTCCCCCTACCACGCATTCTCCCAGGACGAGATACCCTGCCTGGGCCTCTCGAGATAACCGCTCCCCCCAGTGCACCCCCCGTTGCCATAGCTGCCGCACTTGAGCCATCGGCATAGCCTCTCCCCCACTCAAACAGCTAGCCACAGGCCCCTGCAAGTCAATCGCAGGAGCGGGTAGAGGGTGAGGCAATCCGGCATTAAATAGCCGCAACGGCAAGTGCTGGCTAGTCACCAGCGCCCGGGTAATGATGGCCGGTGACGCTCCTGCCATCAACGGCGGTAAGGCATAACGAGGGCGAGGATGGGGACCCTTATAGAGAAATTCCGCGTCTGCCAGTGCCGTCTGCTGTCGATCAGCTGGAGTTGCCCCTGCCGCTGAAATTCCGGGAATCAAGCCCGTAGCCGTAAAGCCAAAGACAATGGCAATATAAGGCCGTCGCCAGCGACAGCAATCTAACCATTGTTGTCCAGCCTCAACCTGAGTATGAACCTGGTTCATGGAGAAGGCAAGCGAGGTTAACTCTCCAACAAGACTTGTACCCAACGAGGAGGGGCAGGCATCGGCATCCCCAGTCGTTCTAGCAACAACCCAGCAGCCAGGTGCACGGTGAACAGGTAAACCACATTGCTGATCACTACCATCACCAGCGCCAATCCCTGAACCGTGAGCAGATCAACCTGGCCCAGAACAGCAACGCCGAGTATACCCAGATCAACCAACCGTTCCAGGATCCAATCCAAGATTTGGGCCATTTGATTGATCAAATACACCCAGAGATCTTCGCCGATCAGCATTGATAACAACCAGATGCGGAAGAAAAATCCCAAACTACCTAACAAAGTGCCCACAGCAATCGAAACATACCAATTGGCCCGACGAAACCACAGGTATCCCAGTTGCACCCCCAAGACTCCATAGGGCATCAGAAACAGTAGGCTGCGAGGGGGTCCCATCAACACCGCTAACAATAGGCTGGCCACCAATGCCGACATCCATGCCGCCCGAGCTCCCCAACGCAAATACACCATGGCCATGGGCACCGGGAAGAAGATGCGGAGCAGAGGTCCTGGCGGAAAGTAGGCATTAATTAGCCAGATCAAACTGGCCGTGCTAGCCAAGAATGCCGTTTCCACCATCACTAAGGGACCGGCCTTACTGGCCAGTTGGTGTCTCAAGCGCTGAGTTCCCACTCCCGATGCCGGAGTATAGGTCAGAAATGCCTCAACGTCCTCAAATTCTGCCTCTATCTCCCGGTCAGAAGAACCATCTGGAGACGATGACGACGATGACGAACTGGCCTGAAATGCCCGGTGGGCAAACGAATCACTCATGACTCCTCAAACTAGCAGACGCTCCAGAGCATCAATGTCTGGAATCCGCATAATATCGCGCTCTCGCACGATCAAAGTCTTTTTCTCCAGTTTGCTGAGAACCCGAGTCACTGTCTCTCGAGCTAGGCCACTCAAACTACTGAGTTCTCGATGGGGTAAATTAGGAATCTCAACGCCATTATCCCCCTCTTGCCCCTGACCATCCGCTAGAAACAAGATAATGTCGGCCACCCGAGACATACTGTCCGACTCTCGGAGACGCAAGCGGCGATTTACCTGACGTAAACGCCGAGCCATGAGTTGAGCCAATCGAATACCCGCAATAGGTTCGGTGTGGATGAGATGCACAAAATCGTTGGCTGGCATATTGCCAATCATGGTGGGCACTAAGGTAATCACATCCGTGGAGCGAGGCACCTCATCTAGGGGAGCCATTTCCCCGAAGACTTCTCCCTTGCCCAAAATATTCAGCGTTACCTCTTTGCCGTCTAGATTGTAGGTACGAATTTTGACCCAACCGTCCAAAATAAAATAAACAGAGGATCCCCAGTCATTCTCTAGCAGCAACACCTGGTTAGCAGGGTGTCGACGAGTAACAACCTGAGCCGTTGCCTGCTGCACTGCGGCGTCAGGAATACCTTGAAAGAAAGGAGCTGAGCGGATCAACTCACTCTCTGAGTGATGATCACGAGGGCCGTAGCGAGGGTCCATAGGTTACTACACTAAGTTCTGGTCAGGGAAACGGATTCGACATGCTATTGAGCCGATAGTCATGCCCGCAGCCCACCACTGCCGCTAGAGACAGTCCAGGCTCAGGGTAGCTATGGGTTACTAGCCATGCTTACCATCTCCCTAAGGGAGTCATCAGGTAAAATCAGCAGGTTTACGGATATATTGGCTATCGTTTTCATCCAGGCTGATCAATAGTGGCCGCAGGGAGTCCTCTGGCAAACTTTCCCAGAAACCTATTAACATACTACCCCGGAGATTTCCTCCCTCTGACCCCGGTGCCACCATCGGTCGACCTCTGGGCATCAATGCGCTTAGCCACGAAGTATTCGTCACGTCTAACTAAGGCATTCTGTGACGTTTTGTGTGAGTTGGCCTACACTTTGGGCAATCCCTCGGTTATCGAGGGCAGTAGCTGATGATTTTCTTGGACTTGGGGGCCTTTATATACCGAGGTGGATTTGGTACCACCGTATTGTAGGCGCTAAATGGGTATGCCTTGATGGATTTAAGGTGGGTAAGGTGACAGAGCAACGGGATCAACTCGAGACGCTAATAGAAGATATCGATGCCCTTTTGAAGAAGGCATCTCCTCGGTTTGGGCGTGGTGCCCAGGAGGACAGTCAACAGCGTCAGATCCTGGAGCGAGCCCGCCAGCACATCCTTGATCTGCAGCAATGGATGACTGCGCCGGGAGGGTGGGGACCAATTGATCCTGCCAGTGGTGCCGTTGACCCTCCTGAGGATTCTAATCCGGATCTTACTGAGTCAGCCCAAACCGTGCTACGGGCATTGCTACAAGAGATGCAATACCTGCGCAGCCAGTTCATTCAACCCTTGCGTACTGAGATAGAGACACTGCAGCAGGAGCGGACTGAGTTACTGGAACAGGTGCGGCAATTAGAAGTGGAGCGTCTCAGGCTGCAAGGACAGTCTCCTGAGCCATCTTCCCAGCAGGAGTGGATACAAGTGGTGGCCCACCACCTAGAGGCCTCCTTAGCAGAGCGCCTTGACCGGGCCGTGGCACGCCGGCAGGCAGAGACGAGTAATCGTCCCCTATTAGAAGGTACACCGCCCCAGCCAGCAGAAGCCGACCTGTCATTGCTAGATCCCCATCAGCGCTTGGCTTATGTGAGGCGAGTTCAGGCTGAAGCCGATCAGGCATTGCTCCAGCTAGACAATACCCTCCGGGCTGTCTTTGCAACTCTGCAACAGAACGCACTCAGCTATCAAGATTCCCTAGCTCAGGGATTAGCCGCCATGCATTCCCTAGGTCAACAGGGAGAAGTCACCCTGCGGGCTCTGATCAGTGATTTGGGGCAGCAACTGCGTCAAGAAGTGGCTTACCTAGAGGCAGCAAGCACTGATGAGCAGGGGCAATTGCTAGCGGCTCAGCAGACATCCCCATCCTCAACAGAGCGGCCTGATGATACCGACACCGATAGCATCTCGACGGCGGCAACGGCTGCTGCAGCTCCTGATCTAGACTGGGAGCTGGCCGACGAAGTTGAGTTTGAAGCCGACGAAGAAATTACTCTGTTGCAACTCGATCAGGAAATCGAGCAGTTGCAACTGGACGCTACGGCAGATCCTTCCCTATTGTTGGAAGAGGACACCGAGACAGAAGCTCCTGACGTATCGGAGCCGACTGCCGCTGCCGCTTCAGACTTTCCTGTCGATCCATTAACCGTGTTAGGGCAACTCGATCAGGCGCTCCCTGATCCTGAGCAGCGGGTAGATGTTCCCGACCGCTCCGTTGATGCCACCATTGCCGCTGCCGCTGAAGAGCTTTTCCCGGATGCTGAGGCTGAGGCTGAGGCTCTCTTTGCGGATCTATTCGGTCCAGCACCAGCATCCTCTAGCCAGGATACCGCCACCGCAGCCGAGCCTTCCATTCCTGACAATGCTGATGAGACTACTGAATCATCTCCTGATGACAGCCTGGCCTCGTCACCAGCGGCAGATGACGATCTTTCTTTAGAGACTGACGAGACCGGAGCGCCCTCAACCAGCATAGACCGGCTAGACGAAATATTGTTTGACGAGGATCTCTTGCAGGTGCCCCCTGAGTCGTCGAACGCAGACCATCTTGGCACTGAGATAGATCTATTTGGGGAAGCTACCGCGGCAACCTTAGAGCAGCCTAGGGTTGAGGTGACCGACACCATACATTCTTTGGATCAGCTTCTCCCGAGCGGCAGCCTTGACCGCGATACTAGCAGCCCTTCCTTGGCCGAATCTGAGGCCCTAGCAGCTGAGCCATTTATTCCTGCCAGTCCCGATGAGGACTTGCTCACTACTGAGACTGATACGGAGTCGGCTTCGTCTCCTCTATCCCTTGATCCAGATATTCTGGCCCAGTTAACCGCTGACCTCTCTCGCCTGGAGGGACCATCGGTATCCGCAGAAGATGGTTTGGAATTCTTAGCTGGGGGGCAAGCCCTAGAGGAGGATGACATCCCCGAGCAGCCGACCGATAGAGAACCAGCCCCCCCACCCCCCTCCTCAGCAGCGACCTGGGCGTCAGACTCGTCTGTCTTTGAAACCACTGTGGATGACTGGAAGACGGCTGTGCAGTCCACGACAGATACCCTGCTAGATGAATCGGGGTTGATGGCTGAGGAGCATGAGGCCGAAACACCAAGCGCCCAAGCGTCGGCTCCCCAGATGTCCTCATCGACTGCAGAGGCGCCGGAGTCTGCCCAGCATCTTGATCTTCCGGATGATGACCTAGATCCCCTCGCGGCTCAAGTGTCAGAGGTTCCCTATGGTTCCCCTAGGGCCGAACATGTTATCGATGCCGTGGGGACATCCCAATCATCGACACCTGAACCAAATTCCCCGGCCGAGTTAGATCCGGACACGCTGACTTGGGAGACCTGGGCGGATGCAGCCGCTACACCTACCTCCATTGAAGCCACCGAGGAGGACTTGGCAGAAACCCTGCCACCAGAGGACTGGCTGTCTATAGATACTAGTCCGGTAGCCACGTCAGAGGCGGATCGGCCTGACGAGACAACGGCTGCACCAGAAATAGAGTCATATACCGCTGAGTGGAAGGACCCAGAGCAGATAGGCACTGAGGAAAATCCCGAGTCGATCGATAGTGCCATCCCGGCGGCCTCTGAGGAGACCCGACAGTCAGCGACTACCTCAGCGCCGGAAGGTGAAGCGTCTTGGTCGTCAGATACCTCCTTGGCAGCATCCCCACTGCCAACGACACCCGAGGCAGCCCCAGCGGCTGAGTCCATGTCTGGAGCGGCTGAGATTGACACACACGAAGCACCGATTGAATCGTCAGAGCAGCTTGAGGCCACTCTAGATGAGCAGCCCCTGGTGGAAACCGACGCCGCTGCTCCATGGCCCTCTGTGGCTGGAGAAGCCCGGGAAGAAACAGCGGCAGCTTCCGCTAATGCCAGGGTCGAAGAACCTCTGCCAGAGATGACCGCATTGTCCGGTTCTGATGCTGAGGAGGGCGGGGCAGAGTGGTCAGAGGTGCTGGCGACTGAGAGCGAGGATGATTGGGTAGGGCAGGATGACACCGACTCTCAGGATAGGGAGCCAGCTATTGCTGGTACGGTGCTGCGTTCCCCTAGTCCTGCCACTGCTGACCCCTCGTCTGAGCACTCTGATTCGGTAGAAGAGGCGCGGTTGGATCAGCCTGGGGCTGAAGACGCAGGCGTGTCGGCATCAACCGACGGTGAGCAGGGCGCAACGGGTGAGTCGCGGCTGGAACCACCATTGGCAACGGCGGAGCCAACGCAGATGGCGGCGACCCCGGCTGGGATGAGTCCTGACGCTTCGGCATTGCCTGGGGAGACCTCGGGCGAGTGGTTTTTAGGGCTAGATATTGGTACCACTGGCCTGTCAGCGGTCTTGCTCAACCGGGCCGATGGTCAGGTGTATCCCCTCTATTGGATCGACTCTACTCTGGCAGATAGTGTGGCCGAGAAGATCTTTCGCTTGCCAGCAGTGGTGTCGATAGCGGCTGACTCGGGGGATACCTCGATGCCGTGGCGGGTGCGATCGCATGGTATGGCTGCCTTAGCTGTGAACTGGGCAGAGGAGGCGGCACATCCCTACCGGCTGCTGACGGCCATGAAGCCGCTCTTGCAGCTGGGCATTCCCTACCAAGCCCCTGATACCCAGCACTGGCAACCACAGTTGCCTTGGCCCGAGGGGGACCCGCTGCCCCTGCAGGCGGTGCAGTTGGGACTGCAATCGCTGCTGCAGACCCTAACCCCTAGCCAAGGGACAGCCCTCGTTTTGGGGGCCACAGACCTCGACCAGCAATCGCTACATCAGGCCATATCCCACTTGCAAGGGGTCATCGTCAACTATCCGGCGGCATGGTCTGATACCTATAGTTTCAACCTGCGGGAAGCGATTCTGGCGGCGGGATTAGTCTCGCAACCCGATGCCATCTACTTCATCGAAGATGCGATCGCAGCGATTCTCTCTGGCCTGCCGGATCCGGACCGCCTCGCCCCGCCCCAAGTTCAGTCCCTGAAGCAGCAGAACCTTTACGGCGGCCAATGGCACGGTGGCACCGTCGTCATCAGTGCTGGGGCCAGCCTCAGCGAAATTGCCGTGGTCAACCTGCCCCACGACGCCGAGGCCCTGAGTCGAGAAGATTTTGTCCTACAGCGGCTAGACTATGGCGGCAATGCCATCGATCTGGACATCATTTGCCAGCTCTTGCATCCCAGTGAGCGTCGCCAACCAACCCAGACATCTGCCGCCCCCGATCCAGATGACACGGGTTGGGGCTGGCAGGCAGCCCTGCCAGAGCTGGCCCATACCCCCTGGAGTAGCCTAGGGCTCTCGCAGCTATCCTTACCCCGGCCAGGGGACCCGGACCTGGAGATGCGATCGCAGCTGCAGCAACGATTAGAATCCTCCTTATTGGGGCAAACCGTCTTGGAAGCAGCCCGCCACCTGAAGCTAATCCTGCAGCACCAATCCCAATTCAACCTGGTCCTAGGGAATCAATGCTGGCAAGTGCGGCGCAAAGAGCTAGAGAGCCAAATCTTACTGCCCTATCAACGCCGACTCAACCAGGCCTTGAATCAGCTGCTGAGTCAAACCGGACTGAGCAATCAAGCCATTAACCAGGTCATTTGCACCGGTGGTACCGCCTCCCTTAAATTTCTCAGTGACTGGCTGCGACAAAAACTCCCGAACGCCACCATCATCCAGGATACTTACCCCAGCAATCGTCCCCCCAGCTGCAGCCGCGTAGCTTATGGGTTAGTCAATCTAGCCCGATATCCCCAACTGCTGGAAAAGACTCGCCATCAATACAGCGACTACTTCCTGCTGCTGGAGCTGTTGCGCACCTTCCCCGATCAGCCGATGCCGCTGGCTGGCATTGTCCATTTGCTCGAGCAACGGGGCATTAACATCCAAGCCTGCCAAGACCACCTCTTCGCACTGCTGGACGGACACTTACCACCAGGCCTACTGCCTCCACCCCAGTGGAGTAGCCATCAGCCTGGCCGACTACAGGCCCTCAGGAGTGTTCCCCTATTTAGCCGCGGGTCGGGCCAGATCTATGTCCCTAACTCAGCCCAGTGTCAGCGACTTTGGGACTATCTCCAGCACATCTTGGCCAATAAGCGCCAGCCCCTGCAAGAGCCCCTCGTGATTCCCCTGTGGACCATGGCCCCAGTCCCCTGATCAATCCGAGGGGATTAAACCATAGAGGAAAACAATAACGGTGCCATCTTTGATAGAATTGAATCTATGGGAAATGGTCCAGGTAGGAGGAGACGAGCCACCTTGCCTTTACCAGCTATCCCTGTCGATTACCGGGTTGATCAGACGGCTGTAGTCAACGGGGACTGCATCCAGATCCCAGGCTAGGGAGCTATCTGATACTCACCCGCTCAACCAACCAAGACATTGGCCAATCAAGGGGGACGTACCGTTGATTCATGCAACGCTACATCAACTGAAAGTATTTGAGGCAACGGCCCGCCATGGCAGCTTTACCCGCGCTGCCGAGGAGCTCTTCTTAACCCAGCCCACTGTCTCGATTCAGGTCAAGCAGCTGACAAAAGCAGTTGGGTTGCCCCTGTTCGAACAAATCGGTAAGCGCCTCTATCTCACCCAAGCCGGCCAAAAACTCTTGGAGACCTGCCAAGAGATCTTCGCAGGGCTGGATCAATTTGAGATGTCAGTGGCCGACCTCAAGGGCCTGAAACAAGGCCAGCTCAAGCTAGCGGTCATTACCACCGCCAAATATTTCGTGCCGCGGCTACTCGGTCCCTTTTGCCAGCGCTATCCCGGCGTTGACATTTCCCTCAAGGTGACCAATCACCAGCATATTCAGGAGCGCATGGCTAACAACGAAGACGATCTTTACATCATCAGCCAGCCCCCTGAACAACCCGATCTCAAGATTTATCCATTCTTGGAAAATCCTTTAGTGGTCATCGCTCCCAAAAATCATCCCCTGGTCGGCAAATCTAATGTCGCCATCCAAGCCCTCAATGATGAGCCCTTTATCATGCGGGAACCGGGTTCAGGGACCCGGCATGCGGTTCAATCTCTCTTTGCCAAGCACAAGATAGACGTGCGGGTACGCTTGGAGCTGGGCAGCAATGAAGCCATTAAACAGGCCATTGCTGGCGGTCTGGGGATCTCGGTCCTGTCGCTCCATACCATTATTTCCGAGGGCACCAGCGGCGAATTTGCCATTCTCGATATCGACCATTTCCCCATCGAGCGGCAATGGTATGTGGCCCATTTGGCCGGCAAACAACTCTCCGTAGTAGCTGACACGTTCTTGACCTACTTGCAAACAGAAAGCCATACCCTGGCCGAGAAATTCTTACCGGGCATCAAACCAGCTAAGGCCAGGCAGGGCAACCTCTCGAAGGCATCGTAGCCGCCGTTGCCTGGCATCTCCTGGTTCGGTGCTTTCTGACAATATTCCAGCAAACAAGTGTCCGTTTCGGGCCGCCTCACTTCATAATGGGGACGATGTCGCAGACTTCGACACCCTATGCCAAGAACGCCCAGCGAATATATCATTCACCTACTATTTGATGGCGGCCACCATCAGGAGGTGCGCTTTTCCAGTATTCAAGAGTTTCAGAAGTGGTACAGCGGTGAGTTAATGCCTAAGGCCAACTCCGATGATTTCATCAGCGTGCCGGTGCCCAAGATCAATCCCGGTGAGTACATGGTGATTCGGCCCTCGCGCCTGGTCAGCATTCGGGTGGAACCCGTCTTTAGCTCTAGTGTGGAGCGCTTTTAGGGATCTGTGGCCATGGTGCGTTCCCTGTCTCAGGGCTTAGGGCTTCTGGCCATCGTCGCCAGCCTCAGCTGGGGCTCGTCTCTGAGAGCTCAACCCTCACCGTTGGAACCGCTGCCGCTGCCACTGGACGAGGTGCTGGGGCCGCAGGGGGGATGCGATCGCAGCCTCTGGGAAACCCCTAGTGAACGGGTGCGGTTAATCCGAGCCATAGGCCATAGCCTCCGCTACCTGGACACCGAGGCGGCGGCCAGCGCCTACGCTACCTATCCCGTCGCTGGGATTACCCACCGGCGAGTACGTCGCAGTCTGGTGCGCTTTCGCCAGTTGCTCTATCAGAGTCGCTCCTTTGCCGACTTTCAGCAGGCTCTGCAGCAGGAGTTTATGCTCTATCGTTCTGTGGGTCAGGATGGTGCCGGAACCGTACTCTTCACCGGCTACTTCCAGCCCACTTACGCCGCCAGTCGGGTGCCCACCGCCGACTATCGCTACCCCCTCTACCGCCGCCCTGCCGACCTAGAACACTGGCCCACCCCGCATCCCACCCGCCTGGAGCTAGAGGGCAGCGATGGCTTGCAAGGATCTCAGGGGCCCCTAGCCGGGCTAGAACTGGTCTGGCTACGGGAGCGCCTGGAAGCCTTTTTGATCCATGTGCAGGGCTCAGCCCGATTGCAATTACCTAATGGTGAGCAACTCTCCGTGGGCTATGCTGGCCGCACCGACTATAACTACACCAGCATCGGCCGCGAGCTGATTAATGACAGTGTCGTCGCCGAGGCCGATCTCTCCTTGCCAGTGCTGCTCGATTATTTTCAGCGGCATCCCGAGGCCCTAGATCACTATCTACCCCGGAACCGACGCTTCATCTTCTTTCAAGAGACTGCTGGCGGACCGCCCCTGGGCAGCCTCAATGTCCCGGTCACCGCTGGCCGCTCCATCGCCACCGACAAAGCCTTGATGCCCCCAGGCGCTTTAGCACTGATCCGCCTGCCCCTGCCCCAGCTGACTGCCGACGGATATTGGCGCAGCCAAACAGTAGACCGTTGTGTCCTTGACCAAGATACCGGCGGCGCAATTCAAGGAGCCGGGCGGGTCGATGTCTTTCTCGGCACCGGCTTCGTTGCCGGTGAACAAGCCGGGCGCCTTCACGGTGCGGGAGAGCTCTATTATCTCTTGCTGCGAGAGAGCCCCTAGCGCTGTTGCCCATCTGGGGATCCAGGCCTGAGTGATGGGTTACTCAGGGGGATCTCAGGCTGGTGCGCTATCTGTAGTCAAAGCATATGCAGAGCGAATTCAGCCTTCCGTATCTATGGAGTCGTCAATTTCCCTCAAGCACCACGTTATTCAAAATCGCATTCGCCAGGTCGGGATTAATGAGAACTACTGGTATCCCGTGGCCTGGTCCCATCAGTTGCCAGTAGGGCAAATTCTTGCCATCACCATTTGGGGCCATTCAATTGCGGTATATCGAGATGTCCAGGGTCAGGTTCATGCCCTGGAAAATGCCTGTCCTCATAAGGGGGTTGAACTGCACTTAGGAGAGGTGCAGGGCGACTGTCTCGTCTGCCCCTACCATGGCTGGCAGTTTAATCCCCAGGGCCAGTGTGTGGCCATTCCCTATTTTCCAGCCGAGCAAAAGTTACCACGAGCTCAAGCTCGCCGCTATCCAGCTGCCGATCAGTACGGCATGATCTGGGTCTTCCCAGGCAATAGCCAACAGGCCTCATCACAGGCAATTCCCGCCATTCCAGAGTATGACGATCCCAATTGCCTAGCCATTCCGATCACCGGCATCTTTGCGGCCCACTTCTCAATTTGCAATGAAAATACGATGGATGTCTTCCATGGGTTTTTACATAAAAATCTTCAGGGCTGGTTCAACCCGGTATTGCTAGATCTGCAGGAGGGTGACGATTACGTGAATGCTCGCTATCAGGTCTCTTATAAAGGGTTTCTCAGTCAGTTTCTAGGGCTAGGTAGCGATAATGCTGGCGTGTCTACTCGTATTGTTTCCATTCATTATCAATACCCCCATTACCACAGCACTTTGGAAGGGGTGTCATCTCTATACCTGATGCGGTTGCCGGTGAGCCCCACTCAAACTCGCTCATTCTCGTGGTTGTTTTTACCCAAAATTCGCCTGCCGAAATGGTTGCTACGGCCCCTGAAGCCAACGGTAGTTCCGCTCATTCGTCGATTGCTATTTATGCCTTTCCTGGAGCAGGATATGGCGATGATGGCCAGCGAACAGCGAACCTATAGCCGCAGCCCCAATCGACAATATGTGGAGGTGAATCCGGCCATTATCGCGCTGCAGCGCGTGATCATGAAGCAATATGAGCTGTACCAGCAACAGATGCGATGGCCAAAGGCCGGTCGTAGACCATCGCACCCCTCAGGGTTGCCTCTGCCGAATTAGCTGGGACGGTAACCAGGGGTGTAAAGTCCGATGGCTAAGGGGCTAGCGTTTGCTAAAGAGTCTGTAAGGGCGCTACCAGCCAATTCTAGATTCGGCTAGGCTGTGACTGAACCATTTGGGTTCATATTCGTCAGTTGTGAAGTAATCCCTATTAAATATTGCGCCTATGTTTGACTGCATTATTGTCGGGGCTGGCCCCGCCGGAGGGACTGCCGCCTATCATCTGGCCAAGCGAGGGCATTCAGTACTCCTGCTAGATAAAGATCCCCTGCCCCGCTACAAGCCCTGCAGTGGTGCAGTCTCACCTAGTGTGGCCCAGTGGTTTGATTTTGATTTCAGCCCCGCCATCGACTTAAAGGTGAGCCGGATTCGCTACACCTGGAAACTCGGGGATGCCATTGATGCCCGCTTAAATACCTCAGAGCCGATCTGGATGGTGAAGCGGGATGTCTTCGACCATTTTCTGGTGCAGCAGGCTCAGCAGCAGGGGGCAACCCTCAAGGACAATACCCCGGTCACAGGCATTACCTTTCAGGGCGATGGCTGGCAGGTGATGACTCCTCAAGGAGCCTTCGATGGCCGCTATCTGATTGCCGCCGATGGAGCTAAGGGACCGATGGCGGGGTGGCTCGGCTTCAAAGACCACAAACCCCGATTGACCAGTCTCTTAGAGATCAGTGCCAAGGCAGACGGCAACTCCGATGCCCCGATTCAGTTTGAGTTTGGCCTGGTCAAGAACGGGTGTTTGTGGAGTTTTCCCAAGCGCCAAGGCTATTCCATCGGGGTGGGTTCTTTCCTGGGCAATAACCTCAAGGACTTCCAATCTCCCCTGGCCGACTATGCCGCCGAACTCGGCCTTTCCCTGAAGCAGGGCACAGAATATCAGCATCCCTTGCAACTGTGGGACGGCAATCGCCCCCTGCATACCCAGCAGGCGCTGCTGGCCGGGGAAGCTGCGGCCATGGTAGATCCCTTGACGGCTGAGGGGATTCGACCGGCCATGTACGGTGGTGTCAAGGCTGCCGAAGCCATTGACGCCGCCCTGCAGGGAGATGCCAAGGCTCTAGCCGCCTACACAGAAGCTATCCAACAGCAATGGGGGGCTGATATGCAGTGGGCTCAGCGCATTGCCGGGTTATTTTATCGAATGCCTGGTCTGGGATTCCGAGTGGGCATCAAGCGACCCACGGCGACTGACCGCTTAGGGCAGTTACTGGCCGGAGACATCCATTATGCTGATATTGCCAATCGAGTAATTAAGCGCCTCAGCGGCAGTCTGATTCCAGGTCGAGGCTAGTAGAGGGGAACGGAGGACGGAAAAGGGGTGGATGGGTGATGGGGTGTTGGCGGAGCCTGCCCGCAGGGCTTTGGGGTGATGGGGTGATGAGGAGTGAGGAGTGAGGAGTGACGAGAAGGAAGGCCCCACGGGTTGATGAGTTTTGAGTTTTGAGTTTTGAGTGAGTGAATGTTTTGGCTCCCTGTCAAACGGTGGATGGGCCGGCAAGTAGGCCGATAGCGGATAAAGGATAAGAGGACAGGGTAGGGGCGCGGTTGCCGCGCCCAATGCAGAAAACCCTCCATCTCGCGTCTCCGCCGATGCGACGCGATCTTGAACGGCTGATCGACCATTCCTTCCGCGGGGTCCAGGGCGGCGGAACGCCCTGGTCGTCGGAGTCCGAGGGGAACGAGATCCCCTCGGGCGAGCTCTCTGGCTTGGAAAACCAAGTGCGGTCTTATCGAGGTCCATCGCTTCCTGGCCGATGCGATGCGACGATCTATCACTACCTATCGACCATCCCATCCGCAGGGTCCAGAGCAATGGTTCGACTGCGCTCACCACAAGCAGGTCTGGGTCGGAGAACGCTCTGGCTGCTGGCCGAGGGTGACGCTCTGGATTCTCGCCTAGGCGAGAATGACGGTACTAGTGTTCAGTATTATTGCCTCGGCCTAGCCAAATAGGTATAGCGCACCCAGGCGCTATGCTCATAGTGTTGTAGCAATAGCTGCGACTCGTGCAGGGTGATCTGCCGATCCTGCAGGGCTTGTTCCGTGCGGCGGCGAATATTTTCCACCAGGTCTTCTGAGTCATACTGCACATAGCCCAGCACTTTTCGGTCATGGTGTCCCCTTTGACTACATGTTCGATCTGATAGCCTTATGGGGGTGAGGTTGGATGTGGACTGCAATTGGTGTCGCCGAACAGGTTGTGGCAGATTGCCCCATAATCTCCTGGTAGGCTCCCCCAGAAATAGGCCCAGATAATAGGGCTCACCAGAGTTAAGGGATGCAACTCGAGTACTGATTTGACATCCCGGAGATCGATAAATTGGTCGATTTTTGCCGTCGCTATCGCAGGTGAGGTCAGCCAAGGTAGCCCGACAACTGGGCTCTTCGTCCAGGCGATGGATGGGCATGATGGGAAAGAGCTGGCCAATGGCCCAAGCATCCGGGGCCGATTGGAAGACGGAGAGGTTGATGTAGTAGATGGAGGCCATGATCTTTTCCAGGTCTTCCAAGTCATCCGGCACATAGTCTTCATGGCGGATGATGGTGCAGATCTTGGCACAGCAGGCCCAGAAGAGTCGTTCTAGTGTGGCCCGTTCGGTGAGGCTGAGGTAGCCGAAGCTAAACAGGCTGATGGCTTCTTCTTTGAACTGGAGGGCGTCGTGGTAGACCTCTTGGTAGTTTTTCAGGCCGATGTTGGCATAGGTCTCGTAGAGTTCGCGGACTAGGGGATGGTCGTCTTCGCCGGGAGGCTCCAGGGTCGCCCCAGTGGGCACGTCACTGCTGCCCAGCACATCGAATACCAGCACGGATTGGTGAGATGCGATCGCACGGCCACTCTCGCTAATCAGGGTTGGCGGCGTTAAGTGACGGGAGGCGCAAGCCTCTTTCACTTCGGCGACGACATCGTTGGCATAATTCTGGATGCTGTAGTTCTTAGACGCGTGAAAATTGGTCTTAGAGCCGTCGTAGTCGACCCCGAGGCCACCGCCCACGTCCAGATAGCGCATATTCGCTCCCAGGGCAGCCAGCTCCACATAAATACGACTGGCCTCGCGCAGGGCATCCTTAATTACGCTAATGGCCGAAATCTGAGAGCCAATGTGGAAATGCAGCAACTGCAAGCAATCCAGCATATTCTCCTGGCGCAACCGTTCCACCACCGTCAGCACCTCGGGAATCGTGAGCCCAAACTTGGCCCGATCCCCGGCTGAGCTACCCCAGCGACCAATGCCCTGGCTGCTCAGTTTGACTCGTACTCCCAGTACAGGCTGGATATCGAGGTGATGACTGGCCTGAATCACCAGATCGACTTCTTCCTGCTGTTCCAGGACGATGATCGGCACCTGCCCCAGCCGCTGCCCTAGCATGGCCGTCTCGATATACTCGCGGTCCTTATAGCCATTACAAATCAATAGGGAGCCAGGGGTGTTCAACGTGGCCAGAGCGATCAATAGCTCAGGTTTGGAGCCCGCCTCTAGGCCAAATTGATGGGGACTGCCAAAGCGAACTAAATCTTCGACCAGGTGCCGTTGCTGATTGCACTTCACCGGAAACACGCCGCGGTAGACGCCGCCATAGCGATAGCGGGCAATGGCCTTAGCAAAACAGGCTTGCAGCCGTTCCAGGCGATCCTGCAAAATGTCGGAGAAGCGAATCAGAATGGGCAGGCCTAGATTGCGCTGCTGCAGAGCCTGAACCAGTTCATAGAGGTCGAGGGAGCCACCTCGTTCCCCCTGGGGGGAGACGGTGATATGCCCGGCAGCATTGATTGAAAAATAGGGATCTCCCCAGCCTTGGATGCGGTACAGTTCTTCACTGTCCTCGATGGTCCACGAGGCACTGGGAGCGAGTAACTGAGCAGTATCATCTGATGACGGTGACTGGGGCTGAGGCTGATAAAGCGATGATGGGATGCGACTCATAGGGGTTCTCCGCCGTTTTAGGCCAACCTCATGATGCCCGCCAGCCCCTCCTGAGGTCCCAAACACAAGGACGGCCTAGGGCTAAGCACTAGGCCAGGAGAGCTGTAGGATTACACAGGCTTACGGGCTCAAATTGTAACAAAGAGCCCTAGGGCTATTGAGGGGGTACCGAGGAATTCCCCTGATCTGGAAAGGGCAGGGATACCACTGGGGATGCACTGTCGATCATGTCGAGGGGAACCTGCTGGACGACCGTCTTGAAAATATCGATGAAGGCGTACACGGCTGGGGGCAGCAGGGCATCCTTCAGGACGATCAATCCGATCACGCGCTCTAGGGGCACTGGAACCTCGGCAACGCGAATGCCTGAGGGGATCGGTTCTGCCGCCAGGCGAGCCATGATGGTGGCCCCTAGCCCCCGTTTCACCATGCCCAGAATGGTGGAATCTTCTTTGACTTCGTAGGTGGGCTTCACGGTCACCCCACATCGCCTCAGATGGCGATCGACGTAGGTGCGATCGCTATCGTGGGCTGGTCCTAAGATCAGCGGGTAGGTGGATAGGTGGGGCCAGGTGAAGGGCTGGGGCGGAGGCTCTGGAGCCGGTGGCAGCAGCACTACGTAGCGATCGTGGAGCAGTTCCCAGGCTTCGAACTCCGGCTGGGTGGGAAGGTAGGTAAAGCCGACATCGGCGCGCCCCTGGCGCAGATCCTCTTCGACTTGCTGAAAGTTTTGGTATTCGTTGATGGTGATGCCTAAGCCGGGATATTGCTGGCGAAATTGCTGGATCACCACTGGCAGCAGATGGGTGGCAACGCTACGAAAACCGGCAATGCGTACCTGCCCGGCCTGCAGGCCCCGAGCCGCTTGGGCTTGGCGACAGAGATGCTCTAGGCCCTGCAAGACCCGGCGCGCCTCTTCGGTGATTTGAGCCCCAATGGGAGTGAGGATGGCCCCCTGACGACTGCGGCTCAAGAGCACCACTCCCAATTCCTCCTCTAGGGTTGCGATCGCATGACTAACAGCCGACTGCGACAAATTTAATTGCAACGCCGCATCACTGAAGGAGCCGCTGTCCGCAATGGTGACCAGGGCCCGCAATTGGGAAATTTTTAGTCGATAGGGGTTAATCTTACCCATACAGTAGACTCCACCCCCCCATGCCGATGATGTGATGGACAATGACAAAATAGTAGCCTTCTTCAGTTCTCCTGTGGGTCCTTCCCTGCCCCCGGATTGCCTGGACAAGGTGCCTTTCAACAATTAGCGTGATCCTAACTCAACTGTCCTCATGCAATCTGGGGGATGCTGATGGTGGTGAGTGCAGTCGAACCACCGCCCTAGATCCCGTGGACGGGCTTGTTGGTGAGTAGTCATAGACCTCGATAAGACCATGCTTAATTGTGCAGCTCGGGGTACTCACCCGGGGAAATTTCGCTTTCCCCGGACCCCTACGACCAGGGCAAACCGCTTGTAGTGTTCGCAAAGCGGCTCCGCAGGAGCAACGAAGTCGAACTACTGCCCTGGACCTGCGGAAGGACTTATCGGTTAGGCGCAATAGATCGCGTCGCATCGGCAAGGACGCGAGGGACCTTTCCCCCTTATTCCCTGTCCCCTCTTCACGCTTTACCCTTCGACTGCGCTCAGGGCAAGCTCTTCACTCTTCACTCCCCGTCTCTCCGTCCTCCGCTCTGCCTATGACCGATAGCCTATTGACCGCCGCCGTCTTATTTGGGGCCACCTTGATTTCCTCTACCTTTGGCTTCGGCAGTGCTCTCTTTGCCATGCCCCTCTTGACCCTGGTGGTTGGCATTGAGACAGCGACTCCCTTGTTCGGTTTGGTTGGCCCCACCATCGCCATCTCGATTGCCATCATGAGCTGGCAAGAGATTCAATTAACCGTCACCAGTCGCCTAATTGCGGCTACCCTCTGCGGCCTTCCCATTGGGGTCTGGCTGATCCGCACCCTTCCTGGGGACTGGTTAGCCGATGGCCTCGGTGTGGCCCTGATTGGGTTTGGTCTCTATCGCCTGGGCCGGGTCACCCTGCCGAGACTGATTCATCCCGGTTGGGCCTACCCCTTTGGTTTCGTGGCCGGCATCCTAGCCGGGGCTTACAACACCAACGGTCCACCCGTAGTGGTCTATGGCAACTTGTGTCGCTGGCCGCCAGAGCGATTTCGAGCCACATTGCAGGGCTATTTTCTGCCAACCGGCTTAGCGATTCTGGCCAGTCATGGTCTCGGGGGGCTTTGGAGTGTTCACATTTTTCAGCTCTATGGTCTCTCGTTGCCCCTGGTCTTCCTAGCCGTCTGGATGGGCCACTGGTTGAATCGACGGCTACCGACCGAGCAATTCGAGCGGTTCTTGTCTGGGTTGCTGCTGGTGCTCGGCAGCTTGATGATTTGGCGCTAGTCCCCAGGCCTGCCTCTCCCTGGGACCTCCCCTCACTGAGCAGTGCTCCACTCTTCGACCGTGGGTCTTACTGCCATGCATTGCTTACCCAGACTCAAGCAGAACGACCCACGAGCAGAAGGACCCACGAGCAGAACGACCCACGTTACCTGCCCAGGATTAAACTTCATGGAAAATCCCAGACATCTTTAAGGCGGCTTTGTTCATCTCAGGGCCTTCAAGACGTATTCTCTAAGAGGTGATTCGCCAAGCAAACTCCTATTAAAACTATATTTTTGGTTTCTGCGCTGATTGGGGCCCAAGGCTCTATCTGAACCTGGTGGACCGTCATCCCCCTAATTCTTAACTATATGAATTTTGCAGCCATGGTTAGATGACCCCTAGCAGTATCTTTGGTGCTGGTCTGACGACTATTGTCACCATGGTTTTCCTAACTCGGTGTCTTTCATGAAATTGATTATTCAAATTCCCTGCTACAACGAGGAGGCGACTCTGCCGATCACCCTGGGAGATTTGCCCCGACAAGTCCCCGGCATCGACGACGTCGAGTGGCTGATCATCAACGATGGCAGCACCGATCGGACGGTGGAGGTGGCGCGAGAATGGGGAGTTGACCATATCGTCGACTTTGATCACAATCGCGGTCTGGCTAAGGCATTTATGGCTGGCTTAGAGGCTAGCCTCAAGGCAGGAGCCGATATCATCGTCAACACCGATGCCGATAACCAGTACTATGCCGGCGACATTCCCCGCCTAGTAGAGCCAATTCTGGCGGGGCAAGCCGAGATCGTCATCGGAGCCCGACCGATTCAACGGATCCGGCATTTTTCTCCGGTCAAGAAGGTCTTGCAAAAACTGGGTAGCTGGGCCGTGCGGATGGCTAGCCGCACCTCTGTGGCCGATGCCCCCAGCGGCTTCCGCGCCATCAGCCGTCAGGCCGCCCTGCAGCTGAATGTCTTCAACGAATATACCTATACTCTGGAGACGATTATCCAGGCGGGGCAGCGGGGCATGGCAGTGATCTCGGTGCCAGTGCATACCAATGACTATCTGCGCCCCTCGCGGTTGGTCAAGAGCATTGTGTCCTATGTGCAGCGCTCCTTGCTCACCATCCTGCGCATCTTTGTCACCTATCGGCCCCTACAATTTTTCACGATTCTGGGGGCGATTCCATTTTCGGCCGGCTTTTTATTGGGCCTCCGTTGGCTCTATTTCTTTTTAATCGTGGGCTCGGATCGCACCCGCGTTCCCAGCTTGATCTTGACGGCCATTTTGATCTTGATTGGTGTCCAGCTCTGGGTCTTTGGCCTGGTGGCCGATCTGCTATCGGTGAACCGCAAGTTGTTGGAAGACATTCAGCTGCGGCTGCGCCGTAACGACATCGAAACGGAACGACAGCGACGGCTGTTGCAGCAGCAATCTTCGTCCCTGAAGGTAGGGCGTTCTGGTCGCTAGCGTTGGCGGTGTTGATTGGAGTGCTTCATGCGAGATCTCTTTGCCCGGGAAGCCTTAGCTCACATTCCTAAGCTCCTCACCCTTCAGGACCGCAATCCCCACAGTCCTACCTATGGCTGCTTCGATCGCAATTTCTGGCAGTACAAGATCATCGATTTTCCCAGTGGCATGGCCCAGGAGTTTGTCTGGCCCTTGGCCCTGGCCTATGACACGGACTTAGCGGGGAATGAGTTCTACCGGCAACCGCGGCTACGGGACTGGGTGGAGGCGGGGATCCGCTATGCGGCGTCTAGTGCCCATCGGGATGGCTCCTGTGATGATTATTTTCCCTTTGAGCGAGCCAGCGGCGCGGCGGCCTTCTCGTTGCTGGCCTGTTTGCAGAGCTATCGGTTGCTGGATCTCGATGATCCCAAGTTGCTGCGGTTCTTTGAGAAACGGGCTGACTGGCTAGCTCACCACCTGGAGAGCGGTCGCCTGACTAACCACCAGGCATTGATTGCGCTGTGTTTGGAGTTGGCGTCTCGGTTGCTGGGCACCGATAAATGGGCGGCTGCCATTCAGAACCGGTTGGAGCTGGTGTTTTCCTGGCAAAATCCGGAGGGATGGTTTCAGGAGTATGAGGGCTGTGATCCGGGCTATCACACCCTGACGCTGGGCTGTTTGGCCTGGCTCTATGATCTACGGCCCAGCTCCCGCCTCAAGGATGCGATCGCAAAGGGGGTCAACCTCACCGCCTACTTTGTCCATCCCGATGGTTCCTACGGCGGCGAATATACCAGCCGCAACACCTACAATTTCTTCCCCCATGGCTTTGAGCGCATCGGCCGCTGGTTTCCGCCAGCCCTCAGTATCAACGACTGCATCCTGGAAGGGCTGGCCCAGGGGAAAGGAGCCTGCTATGCCGATGACCATATCGTGGGGCACCACAGCTGGAGTTATCTACTGGCTTGGCGCGACTTCGTGGCCGAGCGACCGCCACTGAAGCCGCCCTCGATGGGGCGCCTATGGCTGCCCGAGGCCCGTATCTTGATCGACCAGCGGGCCGATACCCGTCTCTACCTGGCCCTGAATAAGGGGGGCGCCTTTAAGGTCTTTCGTGACGAGCGGCTACTGCTCTCCGATACTCAATTTTCCCTGGTGGTGCGTCAGGGCCGCAAGGTGAAAAACGCCGTCGGCCATCTGGTGGGTCCCTATCGCTATCACCTGGGCGAGGACGAGGTCGTGGTGGAAGGGTCCCTGGGCTGGGCCAAGCAGAAGCAGATGACGCCGCTGAATCTGATCATCCTACGATTGGTGATGCTGACGGTGGGTCGCTTCTTCCCCAACCTGATTCGCAAGCTGCTGCAGACCCTGCTGATTACTGGCAAGACGCCAGCACCGTTTCGCTTTCGCCGCCAGTTGCGCTGGCAGCAGGGGCGCTGGCAACTGCGGGACGAACTGCGGGCTGATTCCTGGAGTCAGGTGATGGCCGTTGGCATCGGCCCCGACCAGACCTCTATCTATGTGGTCATGAGTCGCACCTTTCAAACCGGACAGTTGCACCCCTGGCTGGATCTGACCCCCCAGGTACGGCAGTTGTCGCCTGGAGAGCCCCTGATCGTGGAGCGTACCCTATGAAACGATTCGTCTCGATTCTGGTCAGCCTTGGCATCCTGGCCCTGCTCTATCGCCGCATCGACCTGGCGGGGCTATTGCAGGTGTTTCAGACCTGCGATCGCACCTGGATGGCCATCAGCCTGGCCATGGTGATCCCCATCACCGGGGTCACCGCCTGGCGGCTGCAACAGTTGATGCCGCCCAAGGCGGCCCTGGGCGTGGGGGAGGCCAATCGCCTGATCCTGGCCGCCAGCACCCTGAATATGGTATTGCCCTCCAAGATGGGGGATATCATCAAGGCCTACTTCATGCGGGATCGGGGCCATCTCAGCGGCTCCCTGTCCCTGTCTATCGTGGTGTTCGAGAAGACCTGCGATATGCTCTCGCTGCTGCTGTGGTGCGCCTTTGGCCTGCTGCTGTATCCCTACAAGGATGCCTGGTTTGTGCTCATGACTGCCGGCATCATCGGCGGCTTGGCCCTGGGGCTGCTGTTGTTGGGCTCTAAGGGCTTCGCCAAGCTGTTTTTCGGTACGGCTCGCCGCCTGGCACCGGGCAAAGTGGCCGAGAAAGTGCACCGCCTGCAGGCCTCCTGGGGCGAGATGCATGATTACATCTGGTGCGATCGCACCCAGCTGCTCAGAGTCAGCTTCACCTCCGTCTTCATCTGGTTCCTGCATCTGCTGCAGATCTGGTTCTTCATCCTGGCCCTGAAAGCCTGGACCCCATTCCTCACTAACTTGGCCCTCTCCCCCCTGGCGATTCTGGCCGGGCTGCTGCCCCTCACCTTTGCCGGGGTCGGCACCCGCGACGCCGCCCTAGTCTTTCTCTACAGTTCCTACTTCGACGAGGCCACCGGGGCGGCCCTGGGGCTGTTGTGCACTTCTCGCTACTTTCTACCTGCCATCGGCGGCCTGCCCTTCCTGAGCCAATATATGACTGCGGTCAACGCTTTCCGCAAGGGACCCCCTCGCCTCAACCTGGGCCAGCGCCGCTGATGATGAAAGCTAGTCCAAAGGCCGCCCAGTAATAGGGCCGACTACTTTAGCTACCCACAATCAAATTGTGTCAGTTAACCAGCCTAACTACTCTTCCAACTCGCTGGGGTCGATGCCGAGTTGCCGCAATTTTTCCATAGCCCGATTTAACTTGCGCTGGGTCTGGTTACGCTCTTGGTATAGCTCCTCAGGGTCTTTAAATCGCTCTCCATGGGGATAGAACAACGCCAGTCCATCCTCAAACATGTCAAATTTCACACCTAGGGTCGGGGAGGTCCAGGGCAGGTTGAGGCAAGTTAGCAGTACAGGCCGATCATCTGGAGCCTGTCGCGTTAGTCCCCAAAACTCGAGATTATCGGGATCATAGAAGACCATTTCCAGCACCCCATACCGGTCGTAAAACGCTTGCTTCTGAGAAATTTCAGTGGCCGTATTACTGGGAGAGATGATCTCAAAGACCACCTGGGGCGGAATGTTGTCCTCTTCCCACTGCTTGTAGCTACCACGATCGCCATCTGGCCGACCCAGCACCACCATGGCATCGGGGGCCTGGGAGGGAACGGGGGGAGCCTCCACCTGAACCGGATACCAGAGCAGATCCCCTGCGACAAAAGCCGTTTGGTCTTGCAAGAGGTTGCTCAGATTGCTGACCAAACGCACGATCCAACGGTACTGCTTCGTGTTATCAGCCATAGGCTGACCATCGGAGTCGGGGTAGAGATCCGTGGTTACCGTTGCTTGGGTCATGGTCGGATGGCCCCATCATCATACTGCTGGCTAATGCTGGCCCTCATGGGTAACCCCTATTTTGGCAGCCTATCTCAATTCTGGCATTGAAGTCATAGGATAGGATTCTCTAGGCCGATGCTTGGAGCTGATTTTTGGGGAATCCGACATGTGGCCAGTCAAACATGGACAGCGTCACGCCACTGAAATCGAACGGTGGATATACGCCAATCTGCTGGCTAAACTCTTTGAACGGGTTGGACAGAGCCTGTATAAGTTCAGGGTAGTCAGATATAGGGGATAGTAGACCCTACTGAGACATTGAGTTTATGCGACCCCTATTCTCTGGCCTCCTGTTAACTGGATTGACCCTGTCAGCCCTATCGATGCTGCCCCCGCGGGCTCCTGGGGGAGATTTGACCGGCTCTGTTTCTGTGGCTCCGGCCCAGGCTCAGACCCGCGAAGATGAGCTTTACTATACCTTCTATGGTCAGCGCGTCCCCCTCACCTTGCGGCAAGATCAGATCGCCGTGGCTCTGAAATCTCAACCCAGTGGGGCCCGGGGAGGACCTTCGCCCTTTCAACAGCTGCAGCACAACTTGCTGGGTCGGCCTGCCGGGGGGCGTGCCGGTCGTGGCGGTGAGGCGGGGCCAGCCCTAGAGGTAACCCTGCGGCCCTTGGGAAATCGCTACGCGGTGATCGAACTGCCTGAGGTGTCTGCCGAGTTGAGGGCAGCGGTGCAGCAGCGGTTGCAACGGCCCTATGTGGAAGCTACCCTGCCGGTGCTCAGCCGCAGCGGCGAGGAGGACACAATCATTCTGCCCAATGAAATTGTGGTCAGTTTCGAGCCCGATGCCCCTGCCAGCCAGGTGCAGCTGACCCTGAGTCGTTATGGCCTGGAAGAGGTGCGGCCCTTGCGCTTTAGCCAAAACCGCTATCTGGTCAGCCGTCGCGATGGGGCTGGGCTACAGGTGCTGAACGTAGCCAATCAACTGAATGGAGTAGCGGGGATTCAGTCGGCTACCCCCAATTTTGTGCAGACGCTGCCCTACCGAGCCGTGCCCCAGAGTCTGGAGCAGCTTGCGATCGCATCTTCCCGGCCCAACCCCCCCTTAGATAATCTCTTGGCCCGGCTATCTGGCCCTCGGGACTGGCCCGTAGCCACCGATTTATTCCCCCTGCACTGGCACCTCGACAGCACCGCCTTTCGCGGCACCCGCCAACCCCGCACTGACATTCGGGTGACTGAGGCCTGGTCCCAAGGCAGCCAAGGAGAGGGCGTCGTCGTCGCCGTCATCGACAGCCTGATCCAGTGGGACCATCCTGATCTGGCCGATAACCTCTATGCCATTGCCGAAGACCAAGCCGGTCGTCTGCCCGGCGAAGTCCATGGCTGGGATTTCTCGAACCGGGACACCACCTGCCAGGCCGACCGTTGCGCTGTCGGTGACCCCGACACTCGCATCAGTGATGCCGAGTTAGACTTGGTGCGCACCGACTTTCAAAATACCTTTACCCTCTCCGATGGCGAGCTGCTACAAACTTACCGGGGATTGGCCAATCGCATTGCTAATGCCCGTCCAAAGTGGTCACAGCGGCAGATTGCCAATGTCATCCGTGGCTACATTCAGGGAGACATTATGGCCGAATTCCACGGCACCTGGTCTAGCGGGGTAGTGGCGGCCAACCCCGGTAGTGCTCGCGGTGCTGTCGGCGTGGCTCCAGAGGCCGAGATCTTGCCGGTACGGGTGTTTGGCCTCGGTGGCGAAATCACCGTGGCTGCCCTGGTGGAAGCCATTGGCTATGCTGCTGAGCGGGGGGTCGATGTGATCAACCTGAGCCTAGGGGGATTGCTACCGGATCGGGAGCTGACCGACCAGATTATGGCCGTGTTGGATGCCCACCCTGACCTAGTGATTGTGGCCTCAGCTGGTAATGACAGCCTGGATGGTGTCGGGTTCCCGGCGGCGATTCCAGCGGTGATTTCCGTGGGGGCCACCACCCTCGAGGGCGAGCGTACCGTCTATAGCAGTTACGGAGGCGGCCTGGATGTGGTTGCTCCTGGCGGTGACATTAGCCAGGTGCCCATGTATGGCATTCTCACCACTGGCGGCACCTGGGTGCCTGGCTTCTGGCAAGGGATCGAGCAGCCTATCCACCCTTGGAGTTTAGGGTTGGATCCCTTGGGGCATTACGTACAGGTGCAGGGCACCTCCTTCTCGGCTCCTGCCACTACTGGGACGGTAGCGCTGATGCTGGCAGCCAATGGCGATCTGACCCGAGCCCAGGTCAGCCAGATTTTACAGACCACTGCCGATTACGAGGGATTGGCCCTGACCCAGTCAGAGATGAATCAGTATCGCCTGCAGGCAGCGGTGGGCCTAGGTACGGTGGTGGAGAACCAGGTGTTGCGACCCACGGGCATTTTTAGCTTTCCGGAGCCGATTTCCCCGGAGCAGTATTACTTCGGTGGGGGACTAGTGAATGCCGCCGCCGCTGTGGAGCAAGCCCGGAAACTACGCTGAGTGGGCAGATAAAGTGACCATGGCCGCAGCCTCGGCGATGGATGATGCCTAGTCTGCGGCGATGAACGCCCAGGGCGATGGGGGCAATGGCGGGTAGGTGCTCAGTTGCGATCGCATGCCCCCCAGTCAGATCAACCCATACTCCCAGCCATCGACAGGATGACCGGCTCCTGCAACACCATCGCTCTCCAAGCATCGCCAACAGACAGGGGAATCAAATTGGTTATCGTGGGCGCCCTGGGCAATTTATCGATTATTGTGAAATTGGCACAAAATCGTAGCCAGTGCCAGAACGCGATGGATTAGCCGGCTGCACCTCAACCAGCTGCAAACCCCCTCTGCGGTCACCGGCAGGAGTAAAGCGGATCGGCCCTTGCACCCCCTCAGCCTCAAAGGTGTCACTGGCCAAGGCTTGCTGAATACCGGTGCGGGAAGGGGCTTGAGCAATCGCCTCAATCAAAGCTTGGGACGCATCATAGGCCATTGCCGTGGCCCAATTGACATCGGCTCCCCAAAGTTGTCGGGACGCCTGGACAAAGGGGGCATTGGGATCGCCCTGAATATGCCACGGGATCGGCAGCACCATACCAACCGCATTTTGCCCACTCACTTCTAACGTCTTGAGACCATATAGATTGCCGATATCCCCCACCAACTGCAACCGACGCTGATTGACGGTGACCAGCTGTAAGGCCCGATCGACAGTATCGGGCGAGGGGATTAAGGTCAACGCGCCAGCAGCTTGATCTAGGGCATCCTGAATCAAGCGCTGGGGTCTAAAGCCAGAGGTACTCAAATCCCATTCCCCCACCACTTGCCCACCTCGAGCAGAAACCGCCGACACAAACTCGGTTTTCAGAGACTGGCTGTATTGACTGGTGGGATCGTGGGCAACAATCATATTCCTAATAGATGCTTGGCTCAGCAGATAATCAGCCATTGTTCTACCGACAATGGCATTATTGGGAATAATGCGAAAGACATAATCGCTAATCCCTGAAATGTCAGGGCTGGTGCTGACTGGACTAATTAATACCAGCTGATTGTCTGCATAAATTGGTGCCACTGCCAGAGTAACTTGACTGCTCCAGTGTCCCATTACCGCCAATATGTCTGAATTAGTAGCCAATTCGGAGATCACTTGGCGGGCAATATTGGGATCATCATTATCATCCGCGACAATCAGCTTCAAAGGTTCACCATTAATCCCTCCCCTTTGATTGACTTCATGCTGAGCCTGGGCAAAGCCTCGCAGCATTTCGAGGGAAAAGGGAGCCGTATTGACGTCAACAGGCACTAAAACAGCCACCTGATGAGCGGAGCCATCGCCAATCTCGGCATTATTCAGATAGATAAGCGTTTCAGGATCATTGCGATAGAGCTGTCTTGCCGATCTAAAAGCCTGCGCTGCCTGCTCAAACTCGCCATTGGCTAATGCTCGTACCCCCTGCTGTTTGGCGGAACCAAAGGCAGGATTTTCGATGCCCAACGCGTCGGTAGAAATGAGAATATGCTCACCAGCGCTAATCCGTGATTCTTCGGTAACCGCTGGGTCAGGAGTAGACCCTGAACTGGTAATAGACTCTGTGTCAGTCTCTCCTTGCCGATTAAAGAACCAATACCCACCCCCAACGATAGCTAAACCAATCAGAATATAAACAATGGGAGGGGGACCCTTTGAACGCCGAACCATAAATAAAAATTGTAATACTCTAAATCCTGCCTTAGCTGGCAATGATCATATGGCCGTTTGGTTGATCATGCAAATGCTTATCAGCTTGATAAGATCATAAGTCAGTGGTATTGCCAGCAAAATATAGTTGTTTTCCTGGAGTATAGCCACTGCAACAGAAACGTTGTTGCAGTTATTGACTCGAAGATTCGGGATCGATAAATGGCTTGTCATTCATGGCATTGGTCCTCTGCGGCGACTCAGTTAGCTCAGAATTTCGAAGTTTTTTTAACCGTTTTTCAACCTGATCATTCAATGTCATTTTTTCAATGTCAGCTTGCAACTGGTCCTGGGGATCCTCTGACAGCTCGGCATACGCCTCTTCATAAAATGACCGATCTTCAACGACCGCTTTGGCCGCTTCAAACTGTGATTGCGATGACTGGATGTTGAGACTGTCATTGGTCTCTGCTACCAGTCGCAACGCTTCATTGATTTCAGCCATATCCTTCATATGCTGGAATTCAAATTTATAGGCCTCCAGCCGCATGCGTTCGCGATCGAGTTTTTCTTTAGACTGGTTGACTAATGCTTCAACTTGCCGCACTCGTTGCTCTAGCTGGGGTAGGAATCGCTCGATTTGTAAGGCACGGGTCATGGCCAGACGGGCTGCTTCTATATTACCTAACTGCTGCGCCAGAACGGCTTCATGCTCAGCATCTTGCAGTTCTTTGACTTTGATTTCGTATTTTTTCTTGGCCCGCTCGTAACTAGCTGCTTGGGTAGATACAGCCTGTGAGAGCTGCTGAACAGACGTCTGCATGGAGCGTAGAGATTCTTCGGCCGCATTAACAGCACCTTGACTATCCGCTTCTATTGGTCTGCCCCACAACCAGTTCCAGCTAATGACTACGACTCGACCCGCTCGCTCTCCCATCAGCCAGTAGACAAATTTCTTCATGGAGTTGCTCCTTATATTGTTTAAGTCGCTGAAGTTGTCGGCTGTTATTGTCTACTGTCGAGTTCCAGGTCAGAAGCTAACCAGCCTCACCCCAGGCTAAGCAGAAGGCTTTGCGGCTAAGGCCGCCTTGGGATAGGCGATACGCTTGTGGTTGTATTGCTGCCACACTTGCACGAAGATGTCGGCAATGATGCGCATATGCTCCCGGGTTAAGCCTGAATCCACCAGCTGATCATCTTTCCAACGAGCTCGCAAGATTCGGTTGACCATGGTTAGAGCCTCTTCAGGCGTCGCCTCCTTCAGAGAGCGCAACGCCGCTTCGCAAGAGTCGGCCAGCATGACAATCCCCGTTTCCGGTGATTGGGGAATGGGACCGTCATAGCGGAAGTCTTCTTCCCGCACCACCAAGGTAGCGTCCTCAGCCGCCCGTTCTTTAGCCTGATGATAGAAATAGCTGATCAGCATGGTGCCCTGGTGTTCTGGGATAAAGGCCCGCAGTGCCTTGGGCAGGCGGCACTTGCGGGCCATGACAATGCCTTCGGTGACATGCTTCTTAATGATGGTGGCACTCAGCCAGGGATCGGCAATTTGATCGTGCTTATTGGGGCCTCCCATCTGATTTTCGATGAATCCCTGGGGATCATGCATCTTGCCGATGTCGTGGTAGAGGGTGCCAGCTCGGACCAGCTCCACATTGCAGCCCAGCACCCGGGCGGCTGCCTCGGCCAGGCTGGCCACGAACATGGTGTGTTGAAATGTGCCCGGCGCTTCTGATGACAATCGCTTCAGCAAGGGGCGGTTAGGGTTGGACAACTCCGCCAGGCGAATTGGGGTGACTAAATCGAAGACATGCTCTAAGTAGGGACTGAGGCCCAGGGCTAAGATACTGGACACCAGACCATAGGCCCCCTGTAGGGCAGAGCCAGTCAGAATGCCATACCAAGCCGATGGCGACACTGGATTGACAATCAGAGTCAGGATTAGGTAGACCCCACCCTGAGTTAAGCCAATGCCACCCCCTAATAGGGCCAGCTCCTCGCGCGATCGCAACCGAGACGCCACCACACTACCGACCAGGGCACCGACCACGCTAGCTACCAGCGGCACGCTACTGACATTAGTGCCGATAGGAACCAATATTCCCAGCAGAGCGATCACTGTAGCCCCTAGGGCCGACCCATAAAAGCTACCGACCAGTAAGCCCACTGCCGGCAGGCCATAGGCGGCACTACCAAACACCAACAGCCCGGCCGTTGTCATCACCATCAGGGTGATCAACACATAATCCCGTCGCCGTAATCCCCCATGGTAGATATGCTCTACCAGCAGAAATATAGAGACTCCCCCGGCCACCAGAACGCCATAGCCCACAAACCCAAGCCAGTTAAACCGTCGCTGACTGAGATTGAAGTGGTCCAGCAGCACGAAGTCAGCCTGGCTGATGGTTTCACCGGCAGCTACGATGACTTCACCCTGTTGTACAGAGACGGTGACCGGCTCCACCGCTTCAGCAGCTTTTTCTGCTTGCAGGCGAGTGCGCTCAGGATCCTCGATCAGATTTGGAGTAAGCACCGACGTCAGCATCTGAGTAGCCAGGGGGGTGGCCACTGACGGCACAGTCTCCTGAAGCTGTGTCCCAATGGCATCCTTCAATACATCGGACGGTAATCCTGGGGAAATCCCCTGGGTGATCATGCGGTCAGTGACCTGGCGTAAGCCCGTCTTGGTAGCCTGCCATTCCTCTTCGCTGAGCTGTAGCAGGCGAGGACCGAACGGCTGATCCATCTGCTCGATGTCGGTCAAGGTGCGCTGATAACGGCGGCGAACAGACTCAAGTTGATCGCCAAGGGTTGCAAATGCCACTGACGACTCTTGTTGTCGTAGGGTAATCAGCTCTCGGGCCACCTGTTTAGGTTGTGGCGATAGGCTTTGAAATTCCTCATGCTGACGCTGATTACCCTCAGATGGCGAGGATGAGCCCGGTGCCTGCTCTAGCGGCCAAGACTGCACTAAGGACCAAATTGATTGCCACTCCTCTTGGTCAGCGGATTGGATATAGCGTTGCGCCGCTGTGGATAAGCGATGGGTGGGTAGAAAGGGAAGGGTTCCGGCTTGCTGTCTCAGCCGTTCCCCTTGCTGAAGGAGCTGGTCAAGCGACTGCAGCATTGCCTCATTAACGGCTGGATCCAGCATCAGCACCCGCAGTACCCCATTCCGGGCTGCCATTTGCTGGGCCTCTGTAGACTCCGTATCGACGACGGTGGCATCCTTGGGAGCAATGATGGTTTCCGGAGCCTGACTGTCCACCTGCAGCCCAGGTTGGTTGTAGAAGCGCTGCCCCAGTCCTGCTGTCAGGGATAACACTGCCACGGCAAAAATCAGCCGGGGTTGCTTGAGGCGACCTGACTGCCGTCTTGCCCGTCGCGGCGGTGGCGGGGAAGAGGTGTCTGATGGACTAATGGGCACGGCAGGAGAAAACCGATGTAACATGCGGTGAGTGAAGCGAGAAGTGGCAGATCTGGACCCCAAGGACCTCCGGAATGAAACGCGGAGAGAGTTGGTAGATGGCTTCCACCGCTGTTCCACTTGGCCGATTAAGAGCCGGAGTAACTTCATCATGGTTGTCCAGTCTTACGTCCGTAGAGCCTGCACCACAGAGTGGTTAGCAGTGGCAAGTTATATAGAGTGATAGCACTCCGGAGTGAAAGGATGAGAATGTAGCAGTTACCGCGGCTGACTGGTGTTCTCTGGTAGCTGGTCCTTAACACACTGAGTATCGATTAAGCAGCGCCTAGAAAACCCAGTCGAGGCTCTAACGAAACGATACCTCAGTGCAAGCTATGGACCCTGACGGTTGCGAGGTACTTGCCTCAGTTAGAGTGCATAGGCTATAGATTGCCCCCTCGATCACCCGCTGCTAAAGTAGATTGCTCAAATTATTATAGTTCTCCTGCCTGAGACTCACAGGTAGGGCATACCCATCACCGGGATGTTGCTATCGGGATCTGGGGGCAGTTGAGTCATGCGAACCCCAGCCCAACTGGCCAAGAGAGACTCTGCTAGCTGCCAAAGATCTGTTTCGCGGCATCCCCATATCCGTTGTAAAGGGCTGATGGTGGACCTAGATGATGTCATGGCTAGCCGCCAGGATAGGGGAATGATGGACAGCCCTGCGGTGGCAGTTGCCAGCAACCCGATCAACCCGCAAGTCGCGACTGTATCGTTGGCTTCTAGGCCTCGACCCATGGCCAAGCGATAGTCTCCACCACTGCTGTCCAGGTAATGCAGAGCTAGGGCTAGGGGCTGCAGCAGAGGAGAGAGCCGACAGTAGGCGGCAGAGGTCGTCAGGCAATGGCGGAGGTCAGCGATGGGAGCACTAATAGCCACGGGGGGGGCTCGATCGAGCCCCCTAGTTATGTTGGGGACAGCAAACGCAGGGGAGGAGAGACTGGCTTGGCTTAAGTGCTGCCGCAGGTATTCGTGAACAACCCAGACAGCGGCTAAGGCTGCAGGCTCGTAGGCATGGCTTAGGGTCTGCAGCAATCGGTCGCAAGCGTGCTGAGGGTAGCGCAGTCGCCAAGGTAACAGCACTAGGGGCAGGGCTGCTGGGGGGGCAATGGCCAAGGACGTCAGCCGGGGCGTGATTTCTTGAGCTAGGGAGTGACCCAAATGCAGCATTGCTGGGGGCCAAGGCACCGCTTTCATAGGTGGAGACTGTGGTGAAGGCGGTCGGGGCTTGAGGGCATTGCTGGCGGCCAGGGTGACGGCGATGGCCATACCACTGACGAGACTGCGATAGCTATAGATGAGGGGCTGCATCGTGGCAGTCTACCTACTCCGAATAAACGACGGCGTGCTTAAATGGGGGGATGACGCTGGGACTGTCGGTAACTCCCTGGGCAACCCAGGCTGACCTCTAGCCGCTTTGATGTTCCTATGATACGTGCCTGTTCAACTGACGTGCGATGGCCCCAAGCCGGTCGAAAGCCATCGCATCATTGCCACGCCTCCATCGATCGGCGTCAAATCTGGCCCATGCTTCTGGCTACGCTAGTTGGGGTTGCCGGTGGCGATCTATTCACGGCGCAGGCTAGCCAAGCCATAGAGATGGCACCAGCAGGTTCCGTAACTGGCGAGCCACAGCTAACTGCCCTGGGCCAAAATAAAGACCTATCACTGCGATTAGCTCGGATCACTCGGCCCACCCTACAACTTGGTAGCACTGGGGAGACGGTGCAAGAGTTGCAAACTGTTTTACTCTTTCTGGGCTACTATTCAGGTCCTGTAGATGGTCAATATCTGGATGCCACCGAAGAGGCTGTGCGTCAGTTTCAGGCGGCAGCGGGTCTGAATCCTGACGGTGTCGTCGGTCCAGCTACTTGGAATCAGCTCTTTCCATCCCCACCCCGGCAAGCCAATCCACCTAGTACGACAACCTCAGCCTCGACTGTCCCTGAGACTAGTTCAGTGACTCCGGTAGCACCGGCAGAAGCTACCAATCCGACCGCCGCATCGGAAGCCTCATCAACTGCGGCAGAGCCTACCGTTGCCCAGACAACATCAGAGGATTCGGAAGAGGTTGCGGAACCTGCAGGGTCGGAAAAGCCGCCAGAGTCATCCGGTCAGGGTCCTGTGGAGTTGCCTGTGTTGAGATCAGGGTTAGCTGGTCCAGCCGTTGCTCGATTGCAGGAGCGCCTTAGGGTATTGGGAGTCTATGCCGGAGTTATCGATGGCATCTTTGGTCGCCAAACCGAAGCAGCGGTTCGACAAATTCAGCGTCGCTATCAGCTACAGGTAGACGGCATTGTCGGTCCAGCGACTTGGCAAGCCCTATTAGCCAATTAAAGTGGTTCAGGCCTGAGGGCACGATTGGAGCGGGTCGATGCTTCCTCTACTCAGCTTGAACCAACCAAGGCGGCACCGGATCTGCCCACTCTGTTTTGGAGGATTCGAGCTGTTGCGGGGCAGACACTCCATGTTGGACATAGAGCATATAGTTGCCCATCAAAAAATAAACGCCCATCATGGCCGCTGCCGATGACGCCACTAGGAAGCCAGCCAACATCAGAGAAAACTCCTGATCTGCAATGGCTCGCTCCATCAGGCGCAATGCCCAGGCAACTAGGGCAATGACAATGACCAAAATAAGGAGCATCATAAAAGGATTACACTAGGTCGCTGTCGCTGTCGTTCCCTCAGCCACTTCGTCCGATGCCTCTATGGGGGAAAGCACCTAAGCTGAGGAAAGTTTATAAAAGTCTACTTTACGTATTGTAACAGAGACTCATGAAAACGGGAGGGTATTTCTACGCGCTTTGGGCAGATTGGTCTAGCCTGCAACCCTCTTGGGATACAGGGATTAGTCTAGGGGGGCAGGTGGGAATCTACCCAGCCCAATTTCTTCAGCTCTGCCGCACCGTCACTTGATGGTGGGCTAGATAGGCTTTGATCTCACCTACCGAGAGCTGTCCGTAGTGCAGTAGGGAGGCCAGTAGAGCGGCTTCGGCCCCGCCCGCGGTCAAGGCCGCGTGAATGTGTTGGCAAGTCCCGGCGCCTCCAGAGGCAATGATTGGCACGGCTACGGCCTCGGCGATGGTGTGGGTCAGTTCTAAGTCATAGCCAGCCTGGGTACCATCGGCGTCCATACTGGTCAGCAAGATCTCCCCGGCCCCTCGTTCTACGACTTCCTGAGCCCAGGCAACGGCATCTAGGCCGGTGTTGTCGCGTCCACCCCGTACGTAAACATCCCACTCGGGGCGATCTGGAAAGCGACGGCGGGCGTCGATGGCCACAACGATGCACTGACAGCCAAACCGCTCACTAGCTTGGTTAATAAAGTCAGGATTGCGGACGGCGGTTGAGTTAATGCTGATCTTGTCGGCCCCGGCTCTTAACAATTTTTTAATTGTTTCTAAGGATTGAATGCCCCCCCCTACGGTAAGGGGAATAAAAACTTGTTCGGCCGTGCGATAGACCACATCGAAGATGATGTCGCGATCTTCGTGGGTGGCGGTGATGTCTAAGAAAACCAATTCATCGGCACCGGCGTCGTTGTAGGCCTGAGCTAGCTCTACTGGATCGCCCGCATCTCTGAGATTAACAAAGTTGATGCCTTTCACCACGCGACCGGCTTTGACGTCGAGACAAGGGAGAATCCGTTTTGCCAGCATGGGAGTCGATGTCCTGTATTGAGATCTCACTATGACTTTAAAGCAGCCTCTGAGTCAGGACGCTGATACACTGTGGAATGGTTTAACTCGTTGTAATCATTGAAGAGGAGTCCTGGGACCGGAATGGGCTTAGAGATCGGACAAAAGGTAAAGGTGACACGGCTGCGGGATCGAGTGTCTAGGGATTTGGCCAATCGTTTGGGCCAAAGCGGCGTGGTTAGCCAGTATAAAATGGTTGATGGCAGCGATGTGGGCGTTGTGGTGGAGTTTCCCGATAAGTTCTCGAGCTGGTTTTTTGAGGACGAATTAAGCTCTGAGTCATAAAGACAGCCAGATTGTAAGCGTTTCATGGCATTTATTCTTACCTTTCTCGGCAAGGGCGGCAGTGGGCGTAGCACCCTTGCGATCGCAACTGCCCAGAAATTTGCCCGGCAGGGCAAGGCAGTCTTGTTAGCAACTCAGGACGCTGGACCTGTCGTGGGAACTCAGTTGGGGCAATCGCTAACCGCCACGCCCCAGTCGGTCGAAACCAACCTATGGGCCATGCAATTGCGATCGGCTACCCTGCTGGAGCAGAGTTGGGATGCTGTCAAGGCTCTAGAAGCCCAATACCTGCGCACCCCCTTTTTCAAAGAGGTCTACGGCCAGGAGCTCGGGGTCTTACCCGGCATGGACGAGGCCTTAGCCCTAGATGCTCTGCGACGCTATGATGCCAGCGGTGACTACGACGTCATTGTCTACGATGGCGCTGGGGATCAAACCACCCTGCGCATGTTTGGGTTACCTGAGATCCTGGATTGGTATCTGCGCCGCTTTCGCCAGGTCTTCGAAGCCTCAGATTTAGGCAAAGCCTTATCGCCCTTTATTCAGCCCATCGCCAACGCTGTCCTAGCCGGGGATTGGGCAGGGCGACTAGAACAACCCAGCCAACAGGCTGCCGATCTCTTAGGACAGGGCCGCACTGCCATCAACGATCCCACCCGGGTATTGGCTTGCCTAGTCACGACTCCCGAGGCTGCCGCCGTGGCTACGGCCCGTCACCTGTGGGGAGGGGCTCAACAAATCGGCTTGGCCGTAGGGGCGGTCTTGGTTAACCAGACTACGGCTGGAACCCTCGAACCAGAGGTCTTTGCTCCCTTGTCGAACCATGCCATCCCGGCCCTAGCTACCCAGGATTGGGCAGCCTTAATCGACGCTCTGCCTGACTTTAACCAATTGGCTCAATCAGCCCCTCGTCCTATAGTTATTGATGTCCCGGCCAGACGGGTCAGTTTGTTCTTGCCGAGTTTCGATAAGACCCAGGTGACCTTGACCCAATATGGTCCAGAGGTCACGGTAGAAGCGGGCGATCAACGGCGCAATCTGCTGCTGCCAGAAGAATTACGAGGTCGACCGGTGCAGGGCGCTAAATTTCAAGATCGTTCCCTAGTGATTTCGTTCTAGTGCCTACCCTTAGGGCTAACCACCAAGCCCAAAGAACTAATCTTAGGCGATGACCAGTGCTGACGGCCATTGCTGTCATGCGTCATCATAATCCTGGTAAACCTACGTGGTGCGTTTCCGTCATGGCTGACCCTCAGCTACCCACAGATTCACAGCAGGCCGCGTCTAACCGCAGCGGCCAGACTCGCCAACTACTCGGCATGAGAGGGGCCCAAGCAGGTGAGACCTCCATCTGGAAGATTCGTCTGCAGTTGATGAAACCCATCACCTGGATTCCTCTGATTTGGGGAGTTGTCTGTGGATCGGCTTCCTCCGGTAACTTTAGCTGGACAGTAGACAATGTGCTGGTCGCCCTGGCCTGTATGCTGCTGTCAGGCCCGTTACTGGCAGGCTATACCCAGACCCTCAACGACTTCTACGATCGAGAGATCGATGCCATCAATGAGCCCTACCGCCCCATCCCCTCAGGAGCGATCTCTGTCCCTCAAGTAGTCGCCCAAATCTTGATATTACTTGGTGCTGGCATCGCCCTAGCCTATGGCCTCGATCAGTGGGCTGGCAATACATTTCCGACCATTACGGCAACTGCCGTCGGTGGCTCCCTGCTGTCATATATCTATTCGGCTCCTCCCCTGAAGCTGAAGAAAAACGGTTGGCTGGGAAACTATGCGTTGGGAGCTAGCTACATCGCTCTGCCTTGGTGGGCTGGTCATGCCCTCTTTGGCGATCTCAACCTGACCATCATCGGGCTGACCCTGTTTTATAGCCTAGCCGGGTTGGGCATCGCCGTTGTGAATGACTTCAAGAGCGTAGAGGGTGATCGGCAGTTAGGACTGCAATCCCTACCCGTCATGTTTGGGGTCACCGCAGCCGCCTGGATTTGCGTGCTGATGATCGATGTCTTTCAGGGGGGAATCGCCGCCTATCTGATCGGAGTGCACCAGAATGCCTATGCTGTGCTCCTGATTCTGCTAATCATTCCCCAAATCACCTTTCAAGACATGTACTTTCTCAGGGCTCCCCTAGAGAATGATGTGAAATATCAAGCCAGTGCCCAACCATTTCTGGTGTTGGGCATGTTGGTTACGGCCCTGGCCCTAGGAAATGCTGGTGTTTGATTCTAGAGACCCCATCGAGATAGACTCCTCGATGCAGTGGTGCGACGATGATGACCGTGATACTTGGGGTTATGGGGACCTTGGATAGCTTATGTCATTATGGGATGCCCTGATCAAATATCCTCTGGGACACCTGATTGAGCGCATGGGGCCGACTAAACTCCATCATGCCGCCGAGAATCACATGCGTCGCGTCACTCAGGCGAGTGCTTCCACCCCACCCGCCTCTCATCATGCCCGACGACGGCGACGCTCCCCTCACCCTCCGCAGCGACGTCCTCTATATCGGCGTCCTCTATTTTGGGGGGTGTTATTAGTCGCGGCAGGCGTCGCCGGGGGAACAACCCGAGCCTATCGTTTCTGGGTCGCTGCCAACGCCACCCTGCCCGATGATATTTCCCGAGTGCTGACCTACCAACGGGGCGGCACCCTCACCATTGAGGCATCGGATGGCCGTATTTTGCAGAAGTTGGGACCGGCCACCCGAGAGAATATCCAATACGAACAGCTGCCGACTAATTTAGTGCAGGCCTTCATCGCCTCCGAAGATCGCCGCTTTTACGCCCACAATGGCATTGACTTCCAAGCCATCGCCCGGGCAGCTATGGCCAACCTGCGCCAGCGGGAAGTCGTTGAGGGGGCTAGCACCATCACCCAACAGCTGGCCCGCATCGTCTTTCTGAATCAGGAACTGACCTTCCAACGCAAGGTACGGGAGGCACTACTGGCGCTGAAGCTAGAGCAAAATCTCAGCAAGCAGCAAATTCTCGAACGTTACCTCAACCTGGTCTATCTCGGCTCCGGGGCCTACGGAGTTGCCGATGCCGCTTGGGTCTATTTTGGCAAAACGGTCGATCAGCTGACGGTGGCTGAGTCGGCACTGATTGCCGGTATGGCGCCAGCTCCCAGCCTCTACTCGCCTTTGAGTCAACCGGAAGCTGCTCGCCGCCAGCGCAATCGAGTCATTCGCCGCATGCAGGAAATTGGTGCCATTTCTGACCTAGAAGCCGAGGCGGCTCTTGCTACCGCTGTTACCACAACTCCCAATCAACCCAAGTATCTCTACAGCGAATTTCCCTATTTCACCATCCATGTTCAAAACCAGTTGGCTCAAATACTCAGCCCCGAGCAACTAGAAGCGGGCGGATTGGTGGTCGAAACCACGCTGAATATCGATTGGCAGCGCCAAGCTGAATCAGCTGTCACAACGGCCCTAGAACGGCTCGGGCCGCGGCAGCGATTTCGTCAGGGAGCCCTGGTCGCGATTGATCCCCGCAGTGGTGAAATCAAAGCCATGGTTGGGGGAACTGATTTTGACGAAAGCCAGTTTAACCGGGTTACTCAGGCACAACGGCAACCAGGCTCTACGTTCAAAACCTTTGTTTACACCACAGCGATTGCGGCTGGCTTTTCTCCGTATAAGCCCTATGTTGATGCCAAATTTGTAGTCGATGGCTATGAACCCAAGAACTATTCTGGAGACTACAGGGGAACCGTTCCGTTGCGGGACGCGCTGGCATCCTCTATCAATATCGTGGCAGTTAAGCTGCTGCTCGACGTAGGGTTCGATCCAGTCATCCAGATGGCCCAACGTATGGGGATTGAATCGGAACTACTGCCGACCTATTCCCTTAGCCTTGGGGCCTCGGAGGTGACTCTGCTGGAACTGACAAGCGCCTATGGCACCCTGGCTAATCAGGGCAAGCATATGCCTACCCACGCCATTCGACGGGTGTTGAACAGCCAGGGAGAGGTTCTCTACGAGTCAGGGGTTGAGCCTCAGCAGGCAGTAGATGCTGACACTGCTGCCATCATGACTTGGATGTTACAAAGAGGTGGTGCGAGGCGGGCCACAGGTGGTAATGCAACCTTGGTCGTCCCGTGGCAGGTAAGACGGGCACATCCGAAAAAATCGGGATCTGTGGTTTGTTGGTTATATTCCCAGTTGGTAGCCGGGGTGTGGTTGGGGAATGACAATAACCAACCCGACTTGGGGGGCGAGTAAGTTCTGCTGCCTATACCTGGCGCCTGTTTATGGAGGAGCTGGTCGAGTCTTTTGAAGAGGAGCATTTCCTGATCTGCCTAATCTTTCCAACCGCAAGGGCACCATCGAAGCGGAACCGGTCAAGCCTAAGCGGGTACGGGCGGCTAAACCCAACCGTGGTGAGGAGAATGAAGGCACCAATAGGCAGGAGGCCCCGGCTGCTGCCCCCCCGCAGACGAAGACAACGAAGGTACCGGGTCTGGAGAATCGGAACAACCTGCCAGGGAAGCCACTAATCAGGAGCAGGGTGAAGGTGGGGCTGCCGATGAAACGGCTGATCCATCGGTAAGCCCGTCTCCGGCTGGTTCGGAGCAGCCAGTTGATGATGGCGGCAGTGCGCCTCCGGCTCCGGCTCCGGCTCCAGCTCCGGCTCCAGCCCCAACGTCTCCTCCGGCTGGTGATGCCACCTCGAGTGGCAGTTCCCCTGCGGGTGATGGGGAGGGATAACCAGAGATTCGATATAATCTGAGAGCTGTTATCGGAGAAAGGAACTGATGGGTTTTTGCTTGGGTGCAACCACCGGTGAAGCTGGATTTCCTATCGCGTTTACAGCGGTGTATGTAGTGGGGTTCATTGCTGCCGTAGTGATTGGCTCCATTGCCTGGTACAACTCCAAGCGACCGGCCGGTTGGGAAGGCAAGGATCGTCCTGATTTCATTCCTGATATCGAAAAAGACAATGCCGAAAAAGAGTCTTGAGGACCAGAAGGTGAGTCTTATTGGTATGCCCTCGATTGATTCTCCTGCATCCTTGGACCGTATAGGGGGCCTATCAGGGCTGTTGTTGTAGCCAGCCTTGGTAAAGTCGGCGTAGCGCGCGGATGACTTGCGAGTGCAAGTGGTGGCCATTGGTGGAGGTGGGCTGTAAGTTTTGTAGGCGATTCAATAGAGTGGCTTCTTCTGCAGCGACTTCTCCATCGCTGTAGATCAGCCCGCTGATGGCTTCAATCAGAGCCTCACAGTCTTGAGGGGTGGGAGTATCCCCCAGATAGTCTCGAATCCACTGATAACACTGCTCTGGGTTAACGGCGACGAGTTCTTTGAGCAGGGGCCGTACCATGGGATGCTGCTCTAAGTGGTAGCGTGCTGCCAGCTGATGCAAGTACTGCCGTTCTTCAGACTGAACAGCGCCGTCGATCCAAGCAACGCCGATAAGGATGCGCAGGAGTTGTGGAGTATGGGTAGCCGTTGACATGGCTGGGAAGAGAGATGGGCTACGGTCGCGATAGGGTTATCCTAGCGTCTGTTGCTGCAGCTGGCGGATTCTCGTGACATATTGCAAGCCTGGGGCCACCCTGGCTTAAGGCGGTGGAGCCTGTTGCTGTTGGCTACGAAAGCGCAGATATTCCGCGATGGCGGCAATCAAACCGGAGGCCAAGATCAAGAGGACGCTGAGGGCATTGATGTCGGGTTTGACGCCGGTGCGGACTCGGCTAAAGATCTCTAGGGGCAAGGGATTGGCTCCGCCCCCGGCGGTGAAGCTGGAAATGAGCAGGTCGTCCATGCTGAGGACGAAGGCCAGCAGGCATCCGGAAATAATGCCAGGGGTCAGTTGCGGCAGTAGTACCTTGAGCAGGGCTTGGGCTGGGGTTGCCCCCAGGTCGAGGGCTGCTTCTTCTAAGTGGGGATTGAGGCCCTGCAGACGACTGGAGACAACCACGGCAATATAGGCCAGGCAGAACACCATATGGGCGGCAATGATGGTCCAAATACTCAGGGGAATGGCCAGAGAAGCTAGAAATACCAGGGTGGCAACGGCAATGGCGATGTCGGGCACAATCAAGGGCAGGTAGGAAATGCCTCGGTAGAGGGCTTTGCCAGGGAAATAATATTTGCTCAGACCAATGGCCATGAGGGTACCTAGAACGGCAGAGATGCCGACGGCCCCGGTGGCGACGATGAGGCTGTCTTGCAGGGCCGAGAAGATGCGGGCATCGTCGAATAGCAAGCGGTACCAGCGCCAGCTCAGGCCCTGCCAACTAGCACTGTAACGAGAGTCGTTGAGGCTATAGACGGCTAGCACCAAGATTGGCAGGTACATGCCCCCGAACATGAGCAAGGCAAATAGGCCGAGCCAGGGAATGCGGTGGCGTAGGCAGGAGAGAGACGGCATAGATAGGTAGATTTCAGGCTAGTAAACGGCGGCATAAATTTGACTCCCGTAGCCGGGGAGCTGGTGGAATAGGGTGCTGGGGGCTAAGAGTCTGCACCTGTCATCCTTGCCTGGGGCAGAGCTAGGTTTCGGAGACTGAAGATCGATCGCCGTAGCGCAGCAATAATGCGATCGCAACACTGACGGCCAGAATCATGACCATGCTCAGGGCCGAGCCAAAGCCCCAATTGCGGGTCGGTCCTAGAAACTGGTTATAGATCAAACGGGCGATATTCATGCTAGAGGCTCCCCCCAGCAGCGTCGGCACCACGAAATCGCCGACGCTGGTGATGAACACCAGCAGACAGCCAGCGGCGATGCCAGCCAGAGTCTGGGGCACCGTCACCTGCCAGAACCCCTGCAGAGGGGTGGCCCCTAGATCCGCGGCGGCTTCCAATAGCCGGGTATCCAGCTTCTCCAGAGATGCGTAGAGAATGAGCACCATATAGGGCAGAAAGCTGTAGCTCAGGCCAATGAAGACCGCCGCCGTCGTATGTAGCCAGGCCTGGGTGGGCAACCCCAGATGCGCCAACACTAGGTTCAACAGTCCCGTGGGGCGCAAAATGCTGATCCAAGCATAGGCTCGCAGCAGAGAGGAGGTCCACAGGGGCAACACAAAGGCCACTAGCAGCAGATTGCGCCAGCGGCGCGGGGCCTTCAGGGCTAGCCAATAGGCCACCGGGAAGCCCAAGAGGAGACAGATCGAGGTGGTACCGGCAGCGAAATACAAGGAGCGGGCGATCACCCGCAGGTACACCGGCTGCAGAATCTGCAGGTAGTTATCCAGGCCATAGCCCGCCGCCGGCTCCCCTGGCCGCAACCCTGGCACCAGGCTGATATCCAGAATCAACAGGGTGGGTATCACCAGCAGTAGTCCTAGCCAGAGGCCGGCGGGGCCTAACAAGGCAATTGGCCCCAGCAGTCGCCTCAGGCGCTGCCGCAGCCAGATGCTGCCGCGATGTAGCCCCCCCGGTGCCTTGCTCAGAGACAGGAACTGTCATCGCCATGCATCCTCCCGCACGATTCCTCTCCCCTTTATTCTCCTTATATTCCCCTTTAGGCGCTGGTAATTTCAGTCCAATAGCGGTCGTAGGTCTCGAGCACCTCGTTCGGCAGGGGGGCGATGCCTTCACACTTGTCTACCACCTCGGCCGGGGGAAATAGGTCTTGATTGTTTTTCAGCTCAGGACTCAACTGATCGTAAGCGCTCTGGTTGGCGGTGGCGAAAAAGAGCCGCTCCACGGCGTCTTTACACACCTGGGGCTGCAGGATGAAATTAATCCACTCATAGGCGGCATCCACATTGGGGGCCGTGGTGGGAATGGCCATGGTGTCGGTCCAGACCGAGGAGCCGCTGGCGGGGACGATATATTCGAACCGCTCGTCTTCTAGGGTGGCTGCGATCGCATCGGACGAGTAGCTCATCACCATCAATAGATCGCCCCCCAGCAACTCCGTTTCAAAGCCAGAGGTTTTGAAAGAGGCGATGTGGGGTTTTAGTTCCATCAACCGATTAAACGCCGCTTCCAGCTCCGCCGAATCCGTAGAGTTATAGGAATACCCCAGGGACTTCAGCACCGCACCCAGCGTTTCCCGCACGTCCTCCAGCAACGTCAGCCGTCGAGACAGAACATCCTGTTGTTGCCACAGATACTCCCAATCTTGAGGAACCGTTGGCAGGGCCTCCCGGTTGAATAACAGCCCCGTAGTGCCCCAGCAAAAGGGCACACTGTAGCGATTGCCGCGGTCATAGACCGGATCTTGCCACTTGGCTAACAGCGCGTTAGTGCCTGCGAGCCGGTCCTGGTCTAAGGCGGTCAGCAACTCCAGGTTCCGCATCTTGATCACCATGTAATCGGAGGGATAGACGATGCTGTAATTACTGCCGCCTCCTGCTTGCAGCTTGGCCAACATCGCCTCATTGGACTCATAAGTATTAACCACCACCTCGATGCCGGTGGCCTCTGTAAACTGGTCCATCAAGGCTTGGTCCGTATAATTGGCCCAGGTATAGACATAGAGCTTGCCATCGTTACCATTGCCAGTGCCGGTGGGCGTCGCAGAGGGGGGGGCCTCAGACTGCACATTCGTGATGTTCTGCCGACAGTTGGCCAGGGCTAAACTAGCCACCGTTGCAGCGGATCCGTATAAAAATCGTCGCCGCGTAGTGCTAGACAGCCGGCGAGAACCATGAAAGGAAAGGCGTGGTCTGCGGGGCATCGTTAGTCGCTCCTTGCTGAAACTAGAACGCTGAGACTAGAGCAGATAACTCAATCAGACAAGGCATCAGACAGGTTACGGGGCCGGACATTCGGTCTACACACAATCAATCATGTCCCAAGCACCAGGCAGTCTGCCGGAGACCAACGGACATAAACCGGAGTTTGGGGGCGTAACCATCGCCCTGACCGATTTGGCTGCAGTGCCATCAGCTGCGCGCCATTGGTTAACTGCACGATGCAATGGACATGGGTGCCCAAATACATGACATGACTCACCTGGCCCGGATAGCAGTTATGGTCAGTGTCAGGGGGCGATGGGCTGAGATGAATATTTTCGGGACGCACACTGAGAAACACAGCGGCCCCCATGGCCGGTAGCGGCACCGACGTGGGTGGGTGCTGAACCAGCACCCGCAATCCCTGCTGGGTCAACACCCGCAGATGAGTGCCCTGATGCTGCTGGATCTGCCCTGACAGCAAGTTGGTTTCACCGATAAAATCTGCCACAAAGGGCGTTTTCGGGTATTCGTAGATCTCACTGGGGCTGCCCACCTGCTCGATCCGGCCCGCTTGCATGACGGCGATGCGGTCTGACAGGGACAGGGCCTCTTCCTGGTCATGGGTCACCATGATGAAGGTGATGCCCAGGGTCCGCTGCAGATTAGACAGCTCCACCTGCATCTGTTTACGCAACTTCAGATCCAGGGCCCCCAGGGGTTCATCTAGCAGCATCACTGCCGGCCGATTGACCAAGGCCCTGGCCAGGGCTACCCGCTGTTGCTGGCCCCCCGATAGATAAGACGGAAACCGCTGGGCGAAGTTCTCCATCTTCACCAGGTGCAGGGCCTGCTGTACCCGTTGGGCCAGCTGGGCCCGCCCCACCCGTTGCAACCGCAACCCAAAGGCCACGTTATCCCATACCGACAGGTGGTCAAACAGGGCATAGTTCTGAAACACCATATTGACCGGACGCCGGTAGGCTGGCACCCGGCCCATGGGACGCCCCCGAATGATAATCTCACCGGCAGACGGCACCTCGAAACCGGCAATCATCCGTAATACCGTGGTCTTACCGCAGCCAGACGGTCCCAGAATACTGAAGAATTCTCCCTGGTGGATGGCTAAATTGGCTGCCCGCACTGCCGGTTCGCCATCAAAGCTCTTAGACACCTGCCGTAGCTCAACATCCAAAGCGGCTTCTGCCTGAGCGATCGCAGACGGAGGCAAACTGGTTTGAGCCATGGCAGCTGTCTCCTAGAGAAATACCCGGCCCAGGGGCTCAAAGGGGCGAAAATTGGCCATTGATTCCCATTGGCGTTGGCCCTATTGTATCCAGCTCTTGCCGTGGCACCAAATGGCTGGAACGGGTGAGCAAGTAAGTGGGCGAGTAACGAGTAACGAGTAACGAGTAACGAGTAGTGACTTACTTTTCACTCTTCACTCTGCTTCGCACGGGCTAAGCCCTCCGGGCAGGCTACGCCAACGCCCTACACTCTTCACTCTTCACCCTTCACTTCCCCAGCCGGTGAGGGCGATACACTAAGATGGGTGCTGTTTCTTCCTACCCGACTCTGGTTGGCTATGGCTCTGATACCGTTTTCTGCTCCGGTCTCTACCCGCGACACGACACGTACGGTGGGTCGCGACTATCAAGCCGTGGTGCTAATGGCCATCTTGTCGTTGTTGTTGCTGGGAGGCTTTGGCAGCCGCCTGGCCTACCTGCAGCTGATGCAAGGAGACGCGAATCGCCAATTGGCGGAGAATAACCGGATTCGGTTGTTGCCAAAGCGGCCAGCCCGGGGGAGTCTGCTTGACCGCGAGGGGCGACTGCTAGCGGGCAATCGCCTGTCTCACTCGGTGACCCTATGGCCGATTGCGCTACCGAAGTCCCAGTGGCCCGAAGTTATCCGTCGTCTCTCGACCTTGCTCAATATTCCGACTGAGGACATTCAGACCAAACTGGAGCAAGCCGGCTATTCCTCCCTAGAAGCAGTCTCCATCGCCCGGGGCATCAGCCCGGCCCAGGCCACGGCTCTGGCCGAATACAGTGCTGAGCTACCAGCTGTACGGCTGGAGGCGGAAGCGGTACGCAGCTATCCCAATGGCGACCTGGCGGCCCATGTGCTGGGCTATACCGGCGAACTCACCCAGGAAGAGCTGCAAGAGCGCCAGGATGCTGGCTATCGCCTCGGGGATGTAGTGGGTCGCATGGGAGCTGAGGCTGCCTTCGAGGCCGACCTGCGGGGGGAATGGGGTGGTCAACAAGTCGAAATTGATAGCTCTGGCCGAGTGCTGCGGGTGCTGGGCGATAAGCCCGCCATCTCCGGGGAGGATGTGCAGCTGACCCTAGATATAGAGATTCAAAAGGTGGCGGAGGCGGCCTTGGGCGATCAAGTTGGGGCCATCGTTGCCCTCGACCCTAACAATGGAGCCGTGCTGGCCATGGTCAGCCGTCCCGCCTTCGATCCTAATATTTTCTCCACCCAGATTACTCAGGCCCAGTGGCAACAGTTGCAGAGTGCCAGTTACCCCTTCCTGAATCGGGCTTTGCGGGCCTATCCACCAGCTAGCACCTTTAAGATCGTGACGACTTCAGCAGCCTTGGAGTCGGGGCGCTATAGTCCTGGTACCGTGCTGCCCACCTATCCCTATGTGCAGGTGGGCGGAATTCAGTTCTGGGACTGGAATAAGGCAGGCTTCGGACCGCTGGGCTTTACCGGGGCCATGGCCATGAGTAGTGATACGTTCTTCTATCAAATTGCCATGGGCATCAAGCGAGCCCCCTTGATTGAATGGACGCGCCGTTATGGATTCGGTCAGAAAACGGGCATCGAGATCGGGGCCGATGAGAGTGCGGGACTGGTTCCTGACAATGCGTGGAAGATAGAAAACGTCGGCCATGAATGGACCATTGGTGACACCATCAACATGTCCATCGGCCAGGGATTTCTGCAGGCAACGCCACTACAGGTGGCAGGCATGTTTGCGATCGCAGCTAATGGCGGCTATCGGGTCACCCCCCATCTCCTCCACGATCAGGAAGACACCGAAGACTGGCGGGAGCCTATTGGCCTCAGCCCTACCACCATTGACATCTTACAGAAAGGCCTGCGCCGGGTGATCACCAGCGGCACGGCCCGGGCGCTCAACGATGCCAATCTGCCTCCCATCGCTGGTAAGACTGGCACCGCCGAAGCCCCACCGGGTAAATCCCATGCCTGGTTTGGCGGCTATATACCCGCCGCCGACCCCGAGATTCTGGTAGTGGCCTTTGCCGAGCATTCCGGTGGCGGCGGTAGTGCCGTGACCGCGCCCATGGTGAAGCAAGTGCTAGCAGCCTACGTCAACGGCCAATCGCAGTAAGAGGATATTTGGAAAGTACTCTGCGACCTTGCTCCAGACTGGAGTCTGGCCAACGGAACCATACGCTCTAAAACGCCTGCCTTACAGGCCTTTCAGCCGATTTTCAAATGTCCTCTAAGCCCTGTCGGCATGTCCCCAGAGCCTCCAGAACTAATTATCGAAGCCGGCCGCACCGAAGCCCAGTACTGGCGAGACCTCTGGCGCTATCGCGAGCTATTTTACTTTCTGGCCTGGCGGGATATCTTGGTGCGCTACAAGCAAACCGCCGTCGGCGTCGCCTGGGCACTGCTGCGGCCCTTTCTGACCATGGTGGTGTTTACGGTGGTCTTCGGCCGCCTGGCCAAGTTGCCCACAGAGGGAGATGCCCCTTACCCGATTCTGGTGTTTGCGGCCATGTTGCCCTGGCAATTTTTCGCCAATGCCCTAACCGAGTGCAGCAACAGCCTGATTCAAAATGCCAACCTGATTGCAAAGGTCTATTTCCCTCGATTGGTGGTGCCTACCAGTGCCGTCATCGTCAGCTTCGTCGACTTTTTGATCTCGGGGATCATTTTGCTAGGGCTGATGGCCTGGTACGCAGCCGTGCCCTCCTGGCGGATTATCACCTTGCCGGGGTTCATCGCCATCGCCTTCGCGGCGGCCATGGGGGCTGGCCTCTGGTTAGCGGCCCTAAACGTGCAGTATCGCGACTTTCGCTACGTGGTGCCGTTTCTGGTGCAGTTTGGCCTCTACATCTCGCCGGTGGGCTTCAGCAGCAGCATCGTGCCCCAACAGTGGCGGCTGTTGTATTCTCTCAATCCCATGGTGGGGGTGATTGACGGCTTTCGCTGGGCCATCATCGGCGGTGATGTGCAGCTCTACTGGCCCGGCTTCTTGCTGTCCTTGCTGCTGGTGGCCGCATTGCTCTTCAGCGGCATCCTCTATTTTCGCCACATGGAGCGCACCTTTGCCGATATCATTTGATGCCTTAGAAGATTGATGCCTTAGAAGATTCCAAGCTACAGGGTCACTCAGAAACGAGGTTAGCCCTCACCCCTGATGAATGATGGGGATGCGATCGCATCTTACAGCATTGGTCAGTCAGCTTAGGACGTGGATGATCGCCCAATCGCCCAGTCTAGGAAGGTTAGCTGCCTCGCCAATGCACAAAGCATTGTTTAGCCTAAACCTGGAAGGGCTTGAGTCGGAGCCAAAGTTGCTAGTGACATATCCCTGTGCCTAAAGACTAGCAATCCAGGGGACTTCTTACCCCACGGCCACCCCGATTCAGAACGTGGGTGTAGATCATGGTGGTTTTTACATCCTTATGCCCCAGCAGCTCCTGCACGGTGCGAATGTCGTAACCATCTTCCAGCAGATGAGTGGCAAAACTGTGACGAAACGTGTGGCAACTGACGTGTTTGGACACTTTTGCCTGGCGAACTGCTCGCTTGATCGCCCGCTGCAAGCCACTTTCGTGCAGATGGTGACGTCTTGTGACACCACTGCGAGGATCTTGAGAGAATCGTTCTGCCGGAAAGACAAATTGCCAGATCCACTCACGGTCGGCATGAGGATACTTGCGCTCCAGCGCAAAGGGTAGATACACCGAGCCATGTCCTTGTGCCAAATCTTGATGGTGCAATTGTCGAACACCATGCAGATGGTCTTTGAGATCTGCGCTCACACTGGTAGGCAGCATTGTTCGGCGGCTCTCTCCACCTTTTGTATCTCTGACCGTTATCTGTTGTTGGGCAAAGTCGAGATCTTTGACCCGTAGCCGTAGGGCTTCGTTTAACCGCAAGCCACTGCCATAAAGCAGCTTGGCAACTAGCTGATAACTGCCGCTCAGATTTTGCAGCACTGAGTTGACTTCATCAGGGGTGAGCACGGTCGGTAAATGGCGCGATCGCTTTGCCCGCACGGCATTGATATCCACCCCTAGATCTTGCTTCAACACCTGACGATAGAGAAACACGACCGCATTCAGCGCCTGATTCTGCGTTGAAGCCGAGACCTTACCCACCACTGCTAGATGGGTCAAAAACGCCTCTAACTCAGCTTCTCCCATCTCAGCGGGATGCCGCTTTTGATGGAACAAGATGTAGCGGCGAATCCAATAAACGTAGGTTTGCTCGGTGCGATAGGAATAGTGCTTTAGCCGGATTTGGTCTCGGACTTGGTCCAGTAGTTTGCGAGGTTGAGTTTCCATCAGTGGTAGATGCAGTACATACGTATTTACTTTGACGTATGTTTGGCGCAATATCCTGAGAAAACGCGGCAGCTATACTGAAGCTTTCAATATATCTACCCAATATAAACGTACTATATGGACAGCTTGCAGCCTATCCGCCGAATTGGGCGAGATATACTGCGATTAATCCATATATCTGCCCCAAACGGGGTAGATATACTGAAGGAGTCGATCTAATAAGAGTTGGACAGCGCTCGAACACGATCGTGAAACGCACAGTGCCCGATGAGAGAAGTGCTATCTGAACACCTAGCCACGTTCATCCGGTCCCTCCCGGAGAAGCGCGAGTACGCCCGCGACGATCTTCTCGTTCCTGCGCTGAAGGTCGCCGAGGATGCCGACAAGGGGCTTGCCGTGTACGACGCTCCGTTCGGCTGGGGCAACCAAGAAGCGCGTGTGGCCCTGATTGGCGTGACGCCGGGTTTCACCCAGATGCAGATTCTCTATCGCGTAGTGCGGAGGCACCTCCTGTTGGGTGCGAGCCCCGAAGACGCTTGCAGGTTGGCCAAGTACGAAGCCAGCTTTGGTGGCACCATGCGCGGGAATCTCGTTCGGATGCTGGACGAGCTCGGGGTGCCGGAACTCCTCGAGGTCGCATCCACCGCCGATCTCTTTGGTTCCAGTTCCCATCTTCTGCACACCACTTCGGCTGTTCGGTACCCGACGTTCCTCCACGGGCAGAACTACACTGGCAGTCAGCCGCGGCTCGTGAGGTCCGCCTTCTTGATGCGATACGTTCGGGACGTTCTTGCGCCGGAGCTGTCCCGGCTCCATGCTGCAGTCTTCGTTCCACTCGGCAAGAGCGTCGCCGAGGCCTTGGAGCTACTGGAGACCGAGCAGCGCATCCCGGCTGGTCGAACGCTACATGGATTCCCACATCCATCGGGCGCGAACGGTCACCGCGCGCGGCAATTCGAGAAGGGGAAGCCCGCGATGAGGCGGCGGTTCGAGGAGATCTTGTGTGGAGGTGCCTCGGCGGGCGCTGTCCAACAACAGCATGCAGCGGACGGCGCTGCGCGCCGCCGCTGATGCCACACGTTAGGCGGCGCTCCGCGCACTCGGAGGTACGACCATGGAGCTCGTATTCGCCCTACTCGTTGTCGCGATTCTCGCTAGCCTGCCTGCAGCCGTGCTCGTTGTTGGCGTCTTCACAGCTCACGCCAGGCCCGACTCGCCTCTGCTTCGGCACTGGCGGCTCGTTGCCACCGTCGGTTTCTCGGCCTGGGCCTTGCTCACCCTGGTCTCGCACCTCTCCGACGCCCCTGGCTACACGGGCATCGGTTCCGGTCTTGGCATTCTCCTTTTGGTGTTCGTCTTTATCGCCCGCTCCAGAGCTTCCACTCTCTCCTCGGGCACGGCATAGCCGCCCAGGGTGCATCGCGCCGCCTAACAAGGCGCTGCAGCTGACGAGCGCCACGGGAGTCGAATCGGTCCAACGCCGCCCAAAGCGCGCTCCGCGCGCAGGGCGGCTCGTGCCAGCTGGCGGCCACCTCCTGTGGCACAATCGGGGCTCCACCAGCGGCGCTCGCAGCTGAGCGCCTGATCCGTTAGCTGTCTGCCTACAGCAAGCATCTACCTGTGGACGCTCCTGGAAGTTTGGGGCATCTTAGACTTATGCCTTAATCAGTTACCGCTGGAATGGAGTAGCTAGAGAATGAGTAGCTCTGCTTACGAAGGGTTCAACGAAGAGAGCTTCTTCGACCGTGTTGAAGCTCAGTTTGTTAAGAAAGCCCCTAATTTGTCTCAGACGCTTAACATTGCCGTCATTGGAAAAGTCAGTGCGGGGAAAAGTTCCTTAATTAATGCCTTGCTTAAGCTGAGTCGTCGGCAAGCGTTAGAAATTGCTAAAGTTGGTGCCACATCAGGAGTAACTACTGATCTAACAATCCTCAAGCTAGATGAAAAAGTACATCTTGTCGATTCCCCTGGGCTTGATGATGTTCGTACTGAGAATAGCGAGCTAACAAAGAAGTTTCTTAAGCATATAGATGTTGGTATATTTGTAGTAACTGGCTCCTCAGATTCCTCACAAAAGAAAAACTTAGATGATTTGCGACAGCATTGCGATGCTATTTTTGTCGTCCTAAATAAAATCGATGAATGGGATGACTTAGATCCATCTGTCTTAGAAGATATTATTCAACAGTGGAAGACTGATCTTGAAGTAGAGAAAATATACCCAACTTGTGCAAAGGGTTACGATCCTAAAAGTCGTCTCCCTACAATGGATATCAGAGGTGTTGCAAAACTCCGGAATGACATTGGGGATTTCCTTGAAAAAAAAGGTAAAGACCTATTGTTAGCTAGGCACATGGCCCAGAAACAATCTCATGCGGTTAAAATTATTGCAGTAGCTTTAGCCGCTGTAGCTGGAGAAGCTTTTATACCTGGTAGTGCCATTTATATTACAGCTACGCAAGGAGCCGCAATTGCATCTCTGTCTTATCTTTATACTGGCGAAATCCTATCTGCTGAATCGACCCTAAGCATTTTACCTAAATTCGTTGCTGAGACAGCAGGCTCTAATCTTTTTCTGTTTGTAAAATCCTTCTTGCCTCCAACAGGTATCGTCGATGTCGCTGCTGCTGGAGTTGCAGTTGTCATTACGCTAGCATTGCTTGCGACAGTTAATTATCTACTTTCCAATGGAGAGGAGCTGGAGCAGGAAGAACTTCTGCGCTCCAAGTTTAGAACATATCATCAGCAAGCAAAAGATACTTTTAAGGAGTTGGCATTAACTGACGTGCGTGATCTTCCTAGCTGGACAAAACTTGTAAACAAGTTTCTTGGCAGTCGTCAATAATTGATGTTCCTTACTTATTAGACCATATTCTGGATTTGACAATTTAATTGGGTTATTCTGAAAGCATTTTTAGAGTTAGGTGATGGAAGTAATGCCTAAACAGTATCAACCTCAAGACCTGTTCGAAATTGTAGCTGATACCGTTATCAGTATAAAGACAAAGGATGGTTCTGGTAGTGGAGTTATTTTTAACAAAAATGGTATCGCGGTTACTAACAGACACGTTGTTGACACTAATACTAAAGCTCTAGTTGGCTTGAGAAACGGCGATAAGTTTATTGGTAAAGTCATTCGTTCGTATTCAGATATTGATTTAGCCTTTGTAAAATTTGACTTAACTAAGTCTTCATTGCTCAGATCTTCTCTAATTTTTTCTGGTGAAGACTTTAGCCCATGTTGCCAGCGGAAACTTAAAGTTGGGGAGCCTGTGTTTGCAATTGGTCATCCAATGGGTCTTGACTATACCCTGACTCAGGGCATCATTAGTTCTATAGAAAGAACAATTGAGGCGGCTAAGTTTATTCAAATAGATGTGTCTATTAATCCCGGCAACAGTGGTGGTGCCCTTTACACAGCTTATGGAGAATTGGCTGGTATCAATACAATGGGTTACGTGAATTCAGAACATCTAAATTTTGCCATACCCATTGATGAAGTGGTTAAACGATATTCTACTTGGCTTGAAGAAGAGGCTAAAGGATTTACACGCTATTGTGCAGTGTGTGGTTTCTCATCCATTGACGATAAATATTGTGAGAATTGTGGTGCTTCTCTCAAAAGAGATTCTAGTCAAGAAGATGATTTTTTAAGCAAATCAGATCTTGCAGAAGACGTGAAGATGAGTATGAAAAGTGATGCCTTGGCAACTTGCAAAGCTTGCGGGACATCTGTTTCATCAAGTCTCAAATATTGTTCAACCTGTGGTTCTACTTTATAAAAGTGAGTTGAGGTAATATGGGAATTTTTGGGGATTTAATTGAAGGGGTTGGTAGCCTTCTAGGAAACAAGCAAGATAACGAGGTTTCAGTTGGAAGCTATATTCAAATTGTAGAAGCTTTACTTAAAGAACTTGGCGTAGATATCAAAGAGTCTAGACTTGACCTTGAATCTAAAAATGACAGGGGTTGGGTAATTCAGAAAGGTAGTGCCCAGATCATTATTCTGATAGCAGAAAATGATGAAGACGATGATCCTACTATAGAAGTGGTTTCACCCATTCTGAAACTTCCCTCTCAAAACATTCTGCCGTTTTATCGCCGATGCCTTGAACTCAATAGAGGTTTGATTGGATGTGCTGTTTGTGTCAGTGAAGATAAGGTTTTGGTGAGAGCAGAAATACCTCTCAGCGGTCTAAGTCTGGAAAGTATTGCATTGATGATCTTTAATGTCGCAGGAGCGGCAGATCAACTAGATGATGAACTAGCAGAAGAGTTCGGTGCTAAGTTATACGATGAATCCTAAACCACAAATTGACCGTGGTTGATTGCTAAGACTATCACTTGGTAGCAATTTCATTTTGGATAGACAATATTCACGTTGCCCCTATTTTATTGTGCCCCTTAGCCGAGTCCAAACTATGCAAATCACCCTCGACTTACCTGAAGAACTGCTTCAATACTTTGATCAAGATCACCTTTCTCGTGAAATTTTAGAGGCATTAGCGGTACAAGCCTATCAAACTGAAAAAATTACTAGTGCTCAAGTTGGTCGTATTCTGGGTCTACCCTCTCGCTGGGCAGTGGATAGCTTTTTGAAGCAACATTGTGCCTATTTACATTACGATGAGACAGACCTGGAGAGCGATCGTGAAACCCTTCGCCAACTTCGTGCGAATCGAGCTAATAGCGCCTCATGATCGCCGTCTCTGATACTTCGCCAGTTAATTATTTGCTGCTGATTGACCAGATTGATCTGCTTCCTCGCTTGTTTCAGCAAATCATCATTCCCGATGTGGTTCGGAAGGAAATGCTTGATCCCTTGGCACCACCTGCCCTTCAACAATGGATTACTCATCCTCCTTCTTGGCTTACAGTCCAAACTGTTTCCGGGGTTGATACAACCCTCAATGCCCTTGATCCAGGAGAACAAGCTGCCATCACCCTTGCTCAAACCTTGCCAGCAGATTTGCTGATTATCGATGAACGATTGGGAAGACGTGTCGCTAGCGATCGGGGAATCCCGATTATCGGCACCCTTGGAATTCTAGATGATGCCGCAAGTCAAGGGTTGATAGAACTAGCAGATGCAATCGCTCGATTGCAACAGACGAATTTCCGTATTTCTCGTCGCATTATTCAAACATTGCTGGAAAATAGAGCATAGTACAAGTAGGTAGGGTCGGCGAGGAAAGCCAGCTAACACTGCGTGGCAGCGGACGGGCGAAAGTCACTGGTTTTAAGTTCAAGGTTGCCTGCCGCCGCTGCACTTCACCGTTAGCTGTCATACGCTCTAGGCTCAGCGGGTGCTACCAACACGAATGAATGTGTAGACAGTTTGCTCAGTTAAGCTAAAATTCATGAATGCTGCTGGTCAGGATGAGCGATCACTGATAATGGAGACTTCTCTAGTTCATTACGTTGAAAAGACTGATCTAATCAACAAGACAGAAATTGAAAAAGTTATATTGTTAGCCTCTTACTATCAAAGAAATGGTCAGAATGATTTTGAGTTCACAATAGAGTCTGTGTGCAATTGGTTTGAAACTTTAGGTTTACATAAACCGAATAAGTCAAGACTGAAACAAAAAATTAGCAAATCTCGTTCTTTTGTTAAGGGGAAAACTAAAAATTCTTATAGAATCCACGCCAGCGAAATTCAAGCTATTTATAAAAAATATCCTTTTTTGGAAGAGCCATCTGAGGAAATACTATCAACTGATACGATTTTGCCCGCTCCCCTATATGAAAATACACGTGGATATATAGAATCTTTATCCAAACAAATCAATGCCTCCTACGAGAATAATATATTTGATGGATGTGCAGTTTTAATGCGAAGACTTCTAGAGATATGCTTAATTCACTCATATGAACATCAAGGCATTGATTCAGAAATAAAAGACTCTCAAGGGAATTATGAAGTACTTTCTAAAATTGTTTCTAATGCTTTGAATAATTCGAAGCTCTCCCTTTCAAGAAATACCAAAACTTGCTTGGAGGATTTTCGTGCGATTGGGAATTATTCTGCACATAAGATTTATTATAACGCAAGAAAAACGGATATAAAGAAGGTGGTTTTAGAGTATAGGGCAACGATTGAGGAGTTACTGTACAAAAGTGGAATTCGAACATAGGGCAATGGAACCAAGTATTTCAGCGAAGGCGAAAATAAATTTCAAAACTGGCGAGGTTGAATTCGAAGGATCGGAACAGTTTGTAGAAAATCAGCTTAATAATATAGATACCATTGCAGAATATATGGCGCTTCTTATATCTAATAATTCTACAGATGAAGTAGACGAAATTGAGCAAGAAGAGATAGCGGCTGTTGCAGAAGAAGAAGAAGAAAAGTTGGTGACAGTTGGTGAGCAAGATCTTCATGTTCCAGATACTTTTGGTGAGTGGTTTCATGGCTTTAAGGATGATGCCAATGATCTCGACAAGGCGCTTATCACAGCTTTTTATGTGCAAAAACAAGCACCAGATAATGACTTCAAAACATCTGAAGTTAATCAGTCTTTGCAAGATCATGGCATTAAGCTTTCAAACCCCTCAAGCTCATTGAAGCGATTAGCCTCTAAAAAACTACTTTTTCAAACCCGGAAAGTAGGAAAGCTAAAATACATGAGAGTATCTGCAGACGGCGTTAAGCATCTTAAAACGCTACGAAGATAGCATTGCTATTCCTAAGTGATCCTAAAACCAGCTAACACTACGTTGGTGCGGATGGAACAGAGGTTATCGGTTAGAGTTCAGGGTTGTCTGCCGCCGCACAACTTCACCGTTGGACAGCGCTCGAACACGATCGTGAAACGCACAGTGCCCGATGAGAGAAGTGCTATCTGAACACCTAGCCACGTTCATCCGGTCCCTCCCGGAGAAGCGCGAGTACGCCCGCGACGATCTTCTCGTTCCTGCGCTGAAGGTCGCCGAGGATGCCGACAAGGGGCTTGCCGTGTACGACGCTCCGTTCGGCTGGGGCAACCAAGAAGCGCGTGTGGCCCTGATTGGCGTGACGCCGGGTTTCACCCAGATGCAGATTCTCTATCGCGTAGTGCGGAGGCACCTCCTGTTGGGTGCGAGCCCCGAAGACGCTTGCAGGTTGGCCAAGTACGAAGCCAGCTTTGGTGGCACCATGCGCGGGAATCTCGTTCGGATGCTGGACGAGCTCGGGGTGCCGGAACTCCTCGAGGTCGCATCCACCGCCGATCTCTTTGGTTCCAGTTCCCATCTTCTGCACACCACTTCGGCTGTTCGGTACCCGACGTTCCTCCACGGGCAGAACTACACTGGCAGTCAGCCGCGGCTCGTGAGGTCCGCCTTCTTGATGCGATACGTTCGGGACGTTCTTGCGCCGGAGCTGTCCCGGCTCCATGCTGCAGTCTTCGTTCCACTCGGCAAGAGCGTCGCCGAGGCCTTGGAGCTACTGGAGACCGAGCAGCGCATCCCGGCTGGTCGAACGCTACATGGATTCCCACATCCATCGGGCGCGAACGGTCACCGCGCGCGGCAATTCGAGAAGGGGAAGCCCGCGATGAGGCGGCGGTTCGAGGAGATCTTGTGTGGAGGTGCCTCGGCGGGCGCTGTCCAACAACAGCATGCAGCGGACGGCGCTGCGCGCCGCCGCTGATGCCACACGTTAGGCTTCTCATGCTGACTGCCTGACACATCTTTTACTCTAGTCGGCAGGATAGAGAGCGGATGCGAGAGAACCAGATTTGGTCGTAATAGTCGTGCTCCGCTTTTTTGGAGGCAAAACAAGGCTCTGGGTCACGGACTAACAGCGCTATCGGCTCTAGAAGCTGTCGTCCTTTGTGAACGACTCCCTTAAGCCAGCGCAATCCAATCTTGAGGTAGCTGAGTCCGCGCCGCCAATGAGGGTCTACCTGCTGCCTAAGGCCTTCAATCTGAACCGCCATGCCAGTGGTTGTTCCATAAAGCAGTGCAATAGCGGCCACTAGATAAAGTCGCTCAAGGGCTACCGCTGAGCGGATTCGGGAGTCTTCAATCTCGAAAGCTCCTGATTTGCTATCCAAAAACAGCTCCTCTACTCTGAAACGCAACGCGTAGCGCCAGAGCGTCTGCAAGGTAGGCGGTTCATCGGTGATGACGGCCCAAGGCTCTTTGACGCCTTTAAGCGTCGCCAGCACGATGTTGCACTGGTGGGAGCCATCCTGCCACAGCCTGACATTTCGATAGAAAATCGCCTCGCCTTTTGGCGGCCACAGATATCTCACTTCAGTCGGATAACGCCTTGGCCCGTGCAGCAGGACATCGCAGGGCACTCGCAAGCAGTAGTGCCAACTGCTCGCTTGCAACCAACTCATCAAGTCGTGGTTGGCAAAGCCTCGGTCGGCCAGCAGCATTAGGTTCGGGTACTGCCTCAAAAGCCACCGGGCACGGCGCAGCAAAGGGCGGTATTCTTCAAAAGCCACCGTTGCACTGCCATGCTCAAGCACTCGCCACAGTAGCGGGACTGCTCGTCCGCAGCACACCACTGACAGGTGAATCATGCAGTATTGGTTCCACAGCACCGTTGTATCGAGTGCCAGATACAGCCGCTTGCCCTCCCACTGCCTCAGCGTCAGCAGCACCAGCGGTAGGTAGAGCTGATTTATCTCAACGAGCCGGTTGCCGAAAAATCGATGCCACCGCCGCTCGAAGCTTTGCGCTTTGTTGGCACGGCTTATCACGTAGGACTCCCAAGCAGGTGGGCTCAGCTCACCACTACAAATCAGGGCGGTGACCATCCAAGATAGGGCTTTGATATGGCGCAAGTCCCGGTAGTGGCTGTATTGACGCAGATAGTGCAGCAGTTGATCATAGAGCTGGGTAGAGCTTGGCATGTCGCTTTGGCCGTCAGTGTGGTAACTACAGCCTCGCACACGAGCTCTGCCTATTTCCTCTTTGTCCTGATATGACTACCTTTCAGCTACTTCTGTCAGGCACTCAGCTTCTCATGGGCACCTCGAAAAATAGCCAGAGCGATCTCAGTATGAGATCATAAGGTCGGTTTTGTTGAAGCACGCAGGCCATGGGACAGCAGGGATTCTGGGATATCGAAGAGCGCCAGCAAAAACTGGAGCAAAAGAAGGCGGTACTGAATCGGTTGAATCAACTGGTGCCGTGGGAGACCTTTCGTCCGATTCTGATGCAGATTCGAGAGAAACCGCGCAAAAGCCAGGCCGGTCGTAACCCCACCGATGTCCTGTTACTCTTCAAGATGCTGGTGCTGCAAAAGCTATACAACATCAGCGATGACGAACTGGAATATCAGGTCAACGACCGACTGTCCTTCATGCAATTTCTCGGTTTGGGGCTTGAGGATAGAGTCCCGGATGCAACGACGGTGTGGCTCTTCCGAGAACAGTTGCAGCAGCACGGCTTGGTGGAGGCGTTGTTCGAGCAGTTTGGAGCCTATCTGCAAGGGGCAGGCTATGCCGCCAAGGATGGGCAAATTGTGGATGCGACCTTGATTCCAGTTCCCAAACAACGCAACACCCGTGAGGAGAACCAAACCCTCAAGCAGGGTGAGGTTCCCGTTGAGTGGCAAGAGACCCCTCATCAGCTCGCGCAAAAAGATGTTGACGCCCGATGGACGAAGAAAAATGGAACGTCCCACTACGGCTACAAAAACCACATCAATAGTGATGCCGGCTTTAAGCTCATTCGCCGTTACAGCGTCACCGATGCGTCGGTCCATGACTCGCAGGTCTTGGGCGAGTTGCTCGATGCGGATAATAGCGGCGATGGACTTTGGGCCGATAGTGCGTATCTCTCCGTGCTGATTGTCGAGGTGCTGAAATTGATAGGGTTTGAGCCGCATATAAATGAACGGGCCTATCGCAATCGCCCCTTAAGCGAGGCCCAGAAAACCGCGAATCGAGAGCGCTCCAAAACCCGTGCCAGAGTGGAGCACATCTTCGGAGATGTCGTCACCAGCATGGGTGGCAAGGTGGTGCGCAGCATCGGGTTAGCCCGTGCCCAGACCCAGCTAGGTCTGAAAAATCTGGTGTATAACCTGAAGCGGTTTGTGTGTCTCGAAACCCAACGTGCTGCATCGGCTGAACTGGCAAGATAATCGGACCTAAAGCCGGGAAATCGACTTAAACGTGGTCTTCCAACCCTATTTTTTTGTCAAAATGGGAAGCTTTTTTCGGTGGAATGTCTCGGACTCTCTTTGAGTCACCTTGACGGTCTCAAATGAGACGCCATTAGCTAAAGAAAACTGATTAATCGAGGTCCCCTCATGTTATAGGAAAATACAAAATAACAACCTTTAAGCACTAAAGATGTCGTCAATTTGGATAATTCTTCTGGACGTTTCCAGTTCTATGAATGAAGGCTTCTCTGGCAGAGGAGCAACTGATCCTCTAGCAGAACGAGGTGCTTGGCGAACAAAGCTGGAGGCTGCTTCAGAGCTTTTACTGCGCCAGATTGCTTCTATACGTGATCAAGATGTTGCAGTTATTAAGTTCGCTGATCAGGCTGAAAAGATTTTTCAAGGACATCAAAGTGCTTTCTCTCCATCTTCCTTTAGTGTCCTTCAAGGTGGTGGACGTACTAATCTTACTGCGGCGCTCAATATTGTTGCGATTGATTCTTCGTTCAATCGATATCGTGCACTTAGTGTGCTTATACTGTCAGATGGATTAGCAAATATTGGGAACCCTCAAATAGAAGCTGAGCGAATAATTGAGAGATACCCTTTTGCACGAATAGACACCATCCTGATTGATGAAACTGATCAAGGACGAGCAATTGCTGAAAGTGTCTCTATTAATGGTTCTGTTCGAAATGCTGTCTCTATTCTACAACTTCAAGATTCTGTTGAGAGAGCCCGTGTAGCTGGTCTTCAGCAAGAGATTAGTGGTTTAGCGCAGCGACAGCTTGCACTTGAGAGTGAACTGTCTGCAATCGCCAATGTTTCTACACCGACATTACTAACTGTAACTTCTCAAGTCTCTCTCACGCCTTCTTCCTTGCGAGATCAAATCTCACCATTTCTCACTGGAATAGAAGAGATACAAGAGGTTGCATCTACTGCGTCAGGTGCTTCTTATCGAGGTCGTATACGTTCTATATCACAAAGCTCTCCTGTCTCGATCTCTTTATCAGGTCTGCGTGAAGCAGTAGAGCTTTTTCTTGAGTGGATAGTACCTTGGCGTAGAGAGCATGTTGAGCAGATGCTAGTGCTTCAACGAAGGCGGGAAGAGCTTGAACAAAGGAAGCTTGAAATGGATTTAGGTCGTGAGAATGCAGAGCTTGATGCTCTTGAGCTTTCAAATCGCCGTCTTGAACTTGAACTTCTTACTTCCAAGCTAGAACTTGCAGAAAGATTACTCAATCATCTTGACCCTAACGAGAATATGTCGGGATCTGAGCGAGTTGCTTATGTTCAAAAGCTTGTTGGTAGCATAGATCGTCTCGCAAGTAATAGACTCGAATTTCAAGCATCCGGCCCAGGCTTTGAGTCCAGGTCAAATATCCAGTAATAATAATGATTTCAGCTTGCAAACCAGAGAGGTATAAGTGCTAACAATTATAGAACCTTGGTATGCCTAACAATTTCTTGCAGGCGGACGCGAAGGCAAAAGGTTCGGACTTTTCCGAAAGATGGTCTCGCGCCGCTGAAGATTACCGTCAGGCTACTCAATAACCACCAGAGGATTGGCCATGGGTACTTTTGCACAGAAATCAAGGGCAACTCAGCAGATTACATCTGCCAAGCCTGCGATCAAGCCTACGATATCCAGTCGGATCCAGCGGCATGAGTTGCCCCCGCAGTGTCATCGTCCACATCCAGGAGCACTACAGACGAAACTCACGATCGACCAGCCTGGAGACATCTATGAACAGGAGGCAGATCGTGTTGCGAACCAAGTGATTCGCATGCCTGATCCCAAGCTGCAGCGCACCTGTGCCTGTGGTGGTGGCTGTCCCCAGTGTCAGGCACAGCGACCGGAGCAGAAACCAATGCGCCTACAACTGCGGCGCCTTCAGTCGAACAACGAGGAACAGATTTCAGCACTGCCCATCGTCCACGAAGTATTGCGCTCACCCGGCCAGCCCCTGGATGCCCACACCCGCAGCTTTATGGAGCCACGTTTTGGGCATGATTTCAGCCAAGTGCGAGTGCACACGGATGCGAAGGCGGCAGAGTCAGCACAAGCGATCAATGCGCAGGGGTATACAGTGGGCCAGCACGTTGTCTTGGATAACGACCGATTATCTTCAGGGCACCTCGAAAAATAGCCAGAGCGATCTCAGTATGAGATCATAAGGTCGGTTTTGTTGAAGCACGCAGGCCATGGGACAGCAGGGATTCTGGGATATCGAAGAGCGCCAGCAAAAACTGGAGCAAAAGAAGGCGGTACTGAATCGGTTGAATCAACTGGTGCCGTGGGAGACCTTTCGTCCGATTCTGATGCAGATTCGAGAGAAACCGCGCAAAAGCCAGGCCGGTCGTAACCCCACCGATGTCCTGTTACTCTTCAAGATGCTGGTGCTGCAAAAGCTATACAACATCAGCGATGACGAACTGGAATATCAGGTCAACGACCGACTGTCCTTCATGCAATTTCTCGGTTTGGGGCTTGAGGATAGAGTCCCGGATGCAACGACGGTGTGGCTCTTCCGAGAACAGTTGCAGCAGCACGGCTTGGTGGAGGCGTTGTTCGAGCAGTTTGGAGCCTATCTGCAAGGGGCAGGCTATGCCGCCAAGGATGGGCAAATTGTGGATGCGACCTTGATTCCAGTTCCCAAACAACGCAACACCCGTGAGGAGAACCAAACCCTCAAGCAGGGTGAGGTTCCCGTTGAGTGGCAAGAGACCCCTCATCAGCTCGCGCAAAAAGATGTTGACGCCCGATGGACGAAGAAAAATGGAACGTCCCACTACGGCTACAAAAACCACATCAATAGTGATGCCGGCTTTAAGCTCATTCGCCGTTACAGCGTCACCGATGCGTCGGTCCATGACTCGCAGGTCTTGGGCGAGTTGCTCGATGCGGATAATAGCGGCGATGGACTTTGGGCCGATAGTGCGTATCTCTCCGTGCTGATTGTCGAGGTGCTGAAATTGATAGGGTTTGAGCCGCATATAAATGAACGGGCCTATCGCAATCGCCCCTTAAGCGAGGCCCAGAAAACCGCGAATCGAGAGCGCTCCAAAACCCGTGCCAGAGTGGAGCACATCTTCGGAGATGTCGTCACCAGCATGGGTGGCAAGGTGGTGCGCAGCATCGGGTTAGCCCGTGCCCAGACCCAGCTAGGTCTGAAAAATCTGGTGTATAACCTGAAGCGGTTTGTGTGTCTCGAAACCCAACGTGCTGCATCGGCTGAACTGGCAAGATAA

Protein sequences of DBSCAN-SWA_1

>NZ_CP021983|302064:372910|313410_318576_+|WP_088428891.1|DBSCAN-SWA
MGKVTEQRDQLETLIEDIDALLKKASPRFGRGAQEDSQQRQILERARQHILDLQQWMTAPGGWGPIDPASGAVDPPEDSNPDLTESAQTVLRALLQEMQYLRSQFIQPLRTEIETLQQERTELLEQVRQLEVERLRLQGQSPEPSSQQEWIQVVAHHLEASLAERLDRAVARRQAETSNRPLLEGTPPQPAEADLSLLDPHQRLAYVRRVQAEADQALLQLDNTLRAVFATLQQNALSYQDSLAQGLAAMHSLGQQGEVTLRALISDLGQQLRQEVAYLEAASTDEQGQLLAAQQTSPSSTERPDDTDTDSISTAATAAAAPDLDWELADEVEFEADEEITLLQLDQEIEQLQLDATADPSLLLEEDTETEAPDVSEPTAAAASDFPVDPLTVLGQLDQALPDPEQRVDVPDRSVDATIAAAAEELFPDAEAEAEALFADLFGPAPASSSQDTATAAEPSIPDNADETTESSPDDSLASSPAADDDLSLETDETGAPSTSIDRLDEILFDEDLLQVPPESSNADHLGTEIDLFGEATAATLEQPRVEVTDTIHSLDQLLPSGSLDRDTSSPSLAESEALAAEPFIPASPDEDLLTTETDTESASSPLSLDPDILAQLTADLSRLEGPSVSAEDGLEFLAGGQALEEDDIPEQPTDREPAPPPPSSAATWASDSSVFETTVDDWKTAVQSTTDTLLDESGLMAEEHEAETPSAQASAPQMSSSTAEAPESAQHLDLPDDDLDPLAAQVSEVPYGSPRAEHVIDAVGTSQSSTPEPNSPAELDPDTLTWETWADAAATPTSIEATEEDLAETLPPEDWLSIDTSPVATSEADRPDETTAAPEIESYTAEWKDPEQIGTEENPESIDSAIPAASEETRQSATTSAPEGEASWSSDTSLAASPLPTTPEAAPAAESMSGAAEIDTHEAPIESSEQLEATLDEQPLVETDAAAPWPSVAGEAREETAAASANARVEEPLPEMTALSGSDAEEGGAEWSEVLATESEDDWVGQDDTDSQDREPAIAGTVLRSPSPATADPSSEHSDSVEEARLDQPGAEDAGVSASTDGEQGATGESRLEPPLATAEPTQMAATPAGMSPDASALPGETSGEWFLGLDIGTTGLSAVLLNRADGQVYPLYWIDSTLADSVAEKIFRLPAVVSIAADSGDTSMPWRVRSHGMAALAVNWAEEAAHPYRLLTAMKPLLQLGIPYQAPDTQHWQPQLPWPEGDPLPLQAVQLGLQSLLQTLTPSQGTALVLGATDLDQQSLHQAISHLQGVIVNYPAAWSDTYSFNLREAILAAGLVSQPDAIYFIEDAIAAILSGLPDPDRLAPPQVQSLKQQNLYGGQWHGGTVVISAGASLSEIAVVNLPHDAEALSREDFVLQRLDYGGNAIDLDIICQLLHPSERRQPTQTSAAPDPDDTGWGWQAALPELAHTPWSSLGLSQLSLPRPGDPDLEMRSQLQQRLESSLLGQTVLEAARHLKLILQHQSQFNLVLGNQCWQVRRKELESQILLPYQRRLNQALNQLLSQTGLSNQAINQVICTGGTASLKFLSDWLRQKLPNATIIQDTYPSNRPPSCSRVAYGLVNLARYPQLLEKTRHQYSDYFLLLELLRTFPDQPMPLAGIVHLLEQRGINIQACQDHLFALLDGHLPPGLLPPPQWSSHQPGRLQALRSVPLFSRGSGQIYVPNSAQCQRLWDYLQHILANKRQPLQEPLVIPLWTMAPVP
>NZ_CP021983|302064:372910|338944_341464_-|WP_080810708.1|DBSCAN-SWA
MKLLRLLIGQVEQRWKPSTNSLRVSFRRSLGSRSATSRFTHRMLHRFSPAVPISPSDTSSPPPPRRARRQSGRLKQPRLIFAVAVLSLTAGLGQRFYNQPGLQVDSQAPETIIAPKDATVVDTESTEAQQMAARNGVLRVLMLDPAVNEAMLQSLDQLLQQGERLRQQAGTLPFLPTHRLSTAAQRYIQSADQEEWQSIWSLVQSWPLEQAPGSSSPSEGNQRQHEEFQSLSPQPKQVARELITLRQQESSVAFATLGDQLESVRRRYQRTLTDIEQMDQPFGPRLLQLSEEEWQATKTGLRQVTDRMITQGISPGLPSDVLKDAIGTQLQETVPSVATPLATQMLTSVLTPNLIEDPERTRLQAEKAAEAVEPVTVSVQQGEVIVAAGETISQADFVLLDHFNLSQRRFNWLGFVGYGVLVAGGVSIFLLVEHIYHGGLRRRDYVLITLMVMTTAGLLVFGSAAYGLPAVGLLVGSFYGSALGATVIALLGILVPIGTNVSSVPLVASVVGALVGSVVASRLRSREELALLGGGIGLTQGGVYLILTLIVNPVSPSAWYGILTGSALQGAYGLVSSILALGLSPYLEHVFDLVTPIRLAELSNPNRPLLKRLSSEAPGTFQHTMFVASLAEAAARVLGCNVELVRAGTLYHDIGKMHDPQGFIENQMGGPNKHDQIADPWLSATIIKKHVTEGIVMARKCRLPKALRAFIPEHQGTMLISYFYHQAKERAAEDATLVVREEDFRYDGPIPQSPETGIVMLADSCEAALRSLKEATPEEALTMVNRILRARWKDDQLVDSGLTREHMRIIADIFVQVWQQYNHKRIAYPKAALAAKPSA
>NZ_CP021983|302064:372910|303433_303826_+|WP_088428879.1|DBSCAN-SWA
MAFRPNQILYLEHNGRRLYVEVIQIIESRQICWARPLLLVDVSDSQEMPDDISPEHGLHCLQGGPDILWPLAQFQPALDTALLPLLGYLTPSGAFPTSASFSERRLHQPLRQFMDALWMDQQQQFFGQGA
>NZ_CP021983|302064:372910|362477_363332_+|WP_080814167.1|DBSCAN-SWA
MEVMPKQYQPQDLFEIVADTVISIKTKDGSGSGVIFNKNGIAVTNRHVVDTNTKALVGLRNGDKFIGKVIRSYSDIDLAFVKFDLTKSSLLRSSLIFSGEDFSPCCQRKLKVGEPVFAIGHPMGLDYTLTQGIISSIERTIEAAKFIQIDVSINPGNSGGALYTAYGELAGINTMGYVNSEHLNFAIPIDEVVKRYSTWLEEEAKGFTRYCAVCGFSSIDDKYCENCGASLKRDSSQEDDFLSKSDLAEDVKMSMKSDALATCKACGTSVSSSLKYCSTCGSTL
>NZ_CP021983|302064:372910|307824_308406_+|WP_088428883.1|DBSCAN-SWA
MLAAAGLLLGLGIPAWSQTSSPGASTCQVDILGSELAWRQCWLEATPLLSTESDATIVDEDTLSLTTMTRPSLWWRRDQLPSRLGGDRLIEGWTAYHLVDPTMQVIDIDINGQGWRILTLAERYGLLTQFGSAAKAYGYNVRLYRGSDQFRERLALYVCDFSHTPELEGQTSTDSDATAQIPCNAELYDPGQL
>NZ_CP021983|302064:372910|358584_359550_-|WP_080814162.1|integrase|DBSCAN-SWA
METQPRKLLDQVRDQIRLKHYSYRTEQTYVYWIRRYILFHQKRHPAEMGEAELEAFLTHLAVVGKVSASTQNQALNAVVFLYRQVLKQDLGVDINAVRAKRSRHLPTVLTPDEVNSVLQNLSGSYQLVAKLLYGSGLRLNEALRLRVKDLDFAQQQITVRDTKGGESRRTMLPTSVSADLKDHLHGVRQLHHQDLAQGHGSVYLPFALERKYPHADREWIWQFVFPAERFSQDPRSGVTRRHHLHESGLQRAIKRAVRQAKVSKHVSCHTFRHSFATHLLEDGYDIRTVQELLGHKDVKTTMIYTHVLNRGGRGVRSPLDC
>NZ_CP021983|302064:372910|302064_302886_-|WP_088428877.1|protease|DBSCAN-SWA
MGCWPAPLRIGLFLMVLGAAWLPLGLPLYGVEERWTAAGPLALGLLYIVFLGLLPGWGRRIHDLSQPYRTLGLHHPGKMVAGLGVGLALGYLSVGALLGLQIGLGWGTLQPLPLAMGHYVWQGCLVGLGVGMAEELFFRGWLLFELEQDYSMAVALWGDAGLFAIAHYLRPLAAILDSLPQFVGLLLLGLTLVWARRTRLGHRSPSLALPIGLHGGLVGAYYVVDVTDMVRPAAHISPWLTGIGQNPLAGLLGLALLGSLAYGFYRGCHRRLP
>NZ_CP021983|302064:372910|311352_312168_-|WP_088428889.1|DBSCAN-SWA
MSDSFAHRAFQASSSSSSSSPDGSSDREIEAEFEDVEAFLTYTPASGVGTQRLRHQLASKAGPLVMVETAFLASTASLIWLINAYFPPGPLLRIFFPVPMAMVYLRWGARAAWMSALVASLLLAVLMGPPRSLLFLMPYGVLGVQLGYLWFRRANWYVSIAVGTLLGSLGFFFRIWLLSMLIGEDLWVYLINQMAQILDWILERLVDLGILGVAVLGQVDLLTVQGLALVMVVISNVVYLFTVHLAAGLLLERLGMPMPAPPRWVQVLLES
>NZ_CP021983|302064:372910|350394_350817_-|WP_080814153.1|DBSCAN-SWA
MSTATHTPQLLRILIGVAWIDGAVQSEERQYLHQLAARYHLEQHPMVRPLLKELVAVNPEQCYQWIRDYLGDTPTPQDCEALIEAISGLIYSDGEVAAEEATLLNRLQNLQPTSTNGHHLHSQVIRALRRLYQGWLQQQP
>NZ_CP021983|302064:372910|345366_346461_+|WP_080810693.1|DBSCAN-SWA
MAFILTFLGKGGSGRSTLAIATAQKFARQGKAVLLATQDAGPVVGTQLGQSLTATPQSVETNLWAMQLRSATLLEQSWDAVKALEAQYLRTPFFKEVYGQELGVLPGMDEALALDALRRYDASGDYDVIVYDGAGDQTTLRMFGLPEILDWYLRRFRQVFEASDLGKALSPFIQPIANAVLAGDWAGRLEQPSQQAADLLGQGRTAINDPTRVLACLVTTPEAAAVATARHLWGGAQQIGLAVGAVLVNQTTAGTLEPEVFAPLSNHAIPALATQDWAALIDALPDFNQLAQSAPRPIVIDVPARRVSLFLPSFDKTQVTLTQYGPEVTVEAGDQRRNLLLPEELRGRPVQGAKFQDRSLVISF
>NZ_CP021983|302064:372910|364910_365687_+|WP_080814175.1|DBSCAN-SWA
MNAAGQDERSLIMETSLVHYVEKTDLINKTEIEKVILLASYYQRNGQNDFEFTIESVCNWFETLGLHKPNKSRLKQKISKSRSFVKGKTKNSYRIHASEIQAIYKKYPFLEEPSEEILSTDTILPAPLYENTRGYIESLSKQINASYENNIFDGCAVLMRRLLEICLIHSYEHQGIDSEIKDSQGNYEVLSKIVSNALNNSKLSLSRNTKTCLEDFRAIGNYSAHKIYYNARKTDIKKVVLEYRATIEELLYKSGIRT
>NZ_CP021983|302064:372910|344250_345018_-|WP_080810701.1|DBSCAN-SWA
MLAKRILPCLDVKAGRVVKGINFVNLRDAGDPVELAQAYNDAGADELVFLDITATHEDRDIIFDVVYRTAEQVFIPLTVGGGIQSLETIKKLLRAGADKISINSTAVRNPDFINQASERFGCQCIVVAIDARRRFPDRPEWDVYVRGGRDNTGLDAVAWAQEVVERGAGEILLTSMDADGTQAGYDLELTHTIAEAVAVPIIASGGAGTCQHIHAALTAGGAEAALLASLLHYGQLSVGEIKAYLAHHQVTVRQS
>NZ_CP021983|302064:372910|354104_355238_-|WP_080814157.1|DBSCAN-SWA
MAQTSLPPSAIAQAEAALDVELRQVSKSFDGEPAVRAANLAIHQGEFFSILGPSGCGKTTVLRMIAGFEVPSAGEIIIRGRPMGRVPAYRRPVNMVFQNYALFDHLSVWDNVAFGLRLQRVGRAQLAQRVQQALHLVKMENFAQRFPSYLSGGQQQRVALARALVNRPAVMLLDEPLGALDLKLRKQMQVELSNLQRTLGITFIMVTHDQEEALSLSDRIAVMQAGRIEQVGSPSEIYEYPKTPFVADFIGETNLLSGQIQQHQGTHLRVLTQQGLRVLVQHPPTSVPLPAMGAAVFLSVRPENIHLSPSPPDTDHNCYPGQVSHVMYLGTHVHCIVQLTNGAQLMALQPNRSGRWLRPQTPVYVRWSPADCLVLGT
>NZ_CP021983|302064:372910|336468_337908_-|WP_088428897.1|DBSCAN-SWA
MVRRSKGPPPIVYILIGLAIVGGGYWFFNRQGETDTESITSSGSTPDPAVTEESRISAGEHILISTDALGIENPAFGSAKQQGVRALANGEFEQAAQAFRSARQLYRNDPETLIYLNNAEIGDGSAHQVAVLVPVDVNTAPFSLEMLRGFAQAQHEVNQRGGINGEPLKLIVADDNDDPNIARQVISELATNSDILAVMGHWSSQVTLAVAPIYADNQLVLISPVSTSPDISGISDYVFRIIPNNAIVGRTMADYLLSQASIRNMIVAHDPTSQYSQSLKTEFVSAVSARGGQVVGEWDLSTSGFRPQRLIQDALDQAAGALTLIPSPDTVDRALQLVTVNQRRLQLVGDIGNLYGLKTLEVSGQNAVGMVLPIPWHIQGDPNAPFVQASRQLWGADVNWATAMAYDASQALIEAIAQAPSRTGIQQALASDTFEAEGVQGPIRFTPAGDRRGGLQLVEVQPANPSRSGTGYDFVPISQ
>NZ_CP021983|302064:372910|304547_304874_+|WP_088428881.1|DBSCAN-SWA
MYSFDTSMMFMQPSGALSAANAQDFYGQMASQLRSDPVTGLVVDMSQVESLDSAGLNALASALQLAQTLNKTFRLKAVPPSIQIIFELTQLDGVFELADDSAVLPVAA
>NZ_CP021983|302064:372910|363349_363856_+|WP_080814169.1|DBSCAN-SWA
MGIFGDLIEGVGSLLGNKQDNEVSVGSYIQIVEALLKELGVDIKESRLDLESKNDRGWVIQKGSAQIIILIAENDEDDDPTIEVVSPILKLPSQNILPFYRRCLELNRGLIGCAVCVSEDKVLVRAEIPLSGLSLESIALMIFNVAGAADQLDDELAEEFGAKLYDES
>NZ_CP021983|302064:372910|350117_350321_+|WP_088428903.1|DBSCAN-SWA
MGFCLGATTGEAGFPIAFTAVYVVGFIAAVVIGSIAWYNSKRPAGWEGKDRPDFIPDIEKDNAEKES
>NZ_CP021983|302064:372910|302924_303212_-|WP_080810747.1|protease|DBSCAN-SWA
MSVETIERSSTSTIRKPAPRYRVLLHNDDFNTMEHVVESLMKVVPSLTMPQAVDIMMQAHTAEVALVITCALEHAEFYCEGLRGRGLTSSIEPDE
>NZ_CP021983|302064:372910|322743_323874_+|WP_080810724.1|DBSCAN-SWA
MFDCIIVGAGPAGGTAAYHLAKRGHSVLLLDKDPLPRYKPCSGAVSPSVAQWFDFDFSPAIDLKVSRIRYTWKLGDAIDARLNTSEPIWMVKRDVFDHFLVQQAQQQGATLKDNTPVTGITFQGDGWQVMTPQGAFDGRYLIAADGAKGPMAGWLGFKDHKPRLTSLLEISAKADGNSDAPIQFEFGLVKNGCLWSFPKRQGYSIGVGSFLGNNLKDFQSPLADYAAELGLSLKQGTEYQHPLQLWDGNRPLHTQQALLAGEAAAMVDPLTAEGIRPAMYGGVKAAEAIDAALQGDAKALAAYTEAIQQQWGADMQWAQRIAGLFYRMPGLGFRVGIKRPTATDRLGQLLAGDIHYADIANRVIKRLSGSLIPGRG
>NZ_CP021983|302064:372910|369845_371048_+|WP_088428909.1|DBSCAN-SWA
MSSIWIILLDVSSSMNEGFSGRGATDPLAERGAWRTKLEAASELLLRQIASIRDQDVAVIKFADQAEKIFQGHQSAFSPSSFSVLQGGGRTNLTAALNIVAIDSSFNRYRALSVLILSDGLANIGNPQIEAERIIERYPFARIDTILIDETDQGRAIAESVSINGSVRNAVSILQLQDSVERARVAGLQQEISGLAQRQLALESELSAIANVSTPTLLTVTSQVSLTPSSLRDQISPFLTGIEEIQEVASTASGASYRGRIRSISQSSPVSISLSGLREAVELFLEWIVPWRREHVEQMLVLQRRREELEQRKLEMDLGRENAELDALELSNRRLELELLTSKLELAERLLNHLDPNENMSGSERVAYVQKLVGSIDRLASNRLEFQASGPGFESRSNIQ
>NZ_CP021983|302064:372910|350922_351663_-|WP_080814178.1|DBSCAN-SWA
MYLPILVLAVYSLNDSRYSASWQGLSWRWYRLLFDDARIFSALQDSLIVATGAVGISAVLGTLMAIGLSKYYFPGKALYRGISYLPLIVPDIAIAVATLVFLASLAIPLSIWTIIAAHMVFCLAYIAVVVSSRLQGLNPHLEEAALDLGATPAQALLKVLLPQLTPGIISGCLLAFVLSMDDLLISSFTAGGGANPLPLEIFSRVRTGVKPDINALSVLLILASGLIAAIAEYLRFRSQQQQAPPP
>NZ_CP021983|302064:372910|343739_344006_-|WP_080810703.1|DBSCAN-SWA
MMLLILVIVIALVAWALRLMERAIADQEFSLMLAGFLVASSAAAMMGVYFLMGNYMLYVQHGVSAPQQLESSKTEWADPVPPWLVQAE
>NZ_CP021983|302064:372910|331986_332964_+|WP_080810715.1|DBSCAN-SWA
MKRFVSILVSLGILALLYRRIDLAGLLQVFQTCDRTWMAISLAMVIPITGVTAWRLQQLMPPKAALGVGEANRLILAASTLNMVLPSKMGDIIKAYFMRDRGHLSGSLSLSIVVFEKTCDMLSLLLWCAFGLLLYPYKDAWFVLMTAGIIGGLALGLLLLGSKGFAKLFFGTARRLAPGKVAEKVHRLQASWGEMHDYIWCDRTQLLRVSFTSVFIWFLHLLQIWFFILALKAWTPFLTNLALSPLAILAGLLPLTFAGVGTRDAALVFLYSSYFDEATGAALGLLCTSRYFLPAIGGLPFLSQYMTAVNAFRKGPPRLNLGQRR
>NZ_CP021983|302064:372910|371445_371808_+|WP_088431479.1|DBSCAN-SWA
MPDPKLQRTCACGGGCPQCQAQRPEQKPMRLQLRRLQSNNEEQISALPIVHEVLRSPGQPLDAHTRSFMEPRFGHDFSQVRVHTDAKAAESAQAINAQGYTVGQHVVLDNDRLSSGHLEK
>NZ_CP021983|302064:372910|346583_347579_+|WP_080810691.1|DBSCAN-SWA
MADPQLPTDSQQAASNRSGQTRQLLGMRGAQAGETSIWKIRLQLMKPITWIPLIWGVVCGSASSGNFSWTVDNVLVALACMLLSGPLLAGYTQTLNDFYDREIDAINEPYRPIPSGAISVPQVVAQILILLGAGIALAYGLDQWAGNTFPTITATAVGGSLLSYIYSAPPLKLKKNGWLGNYALGASYIALPWWAGHALFGDLNLTIIGLTLFYSLAGLGIAVVNDFKSVEGDRQLGLQSLPVMFGVTAAAWICVLMIDVFQGGIAAYLIGVHQNAYAVLLILLIIPQITFQDMYFLRAPLENDVKYQASAQPFLVLGMLVTALALGNAGV
>NZ_CP021983|302064:372910|334019_336215_+|WP_088428895.1|DBSCAN-SWA
MRPLFSGLLLTGLTLSALSMLPPRAPGGDLTGSVSVAPAQAQTREDELYYTFYGQRVPLTLRQDQIAVALKSQPSGARGGPSPFQQLQHNLLGRPAGGRAGRGGEAGPALEVTLRPLGNRYAVIELPEVSAELRAAVQQRLQRPYVEATLPVLSRSGEEDTIILPNEIVVSFEPDAPASQVQLTLSRYGLEEVRPLRFSQNRYLVSRRDGAGLQVLNVANQLNGVAGIQSATPNFVQTLPYRAVPQSLEQLAIASSRPNPPLDNLLARLSGPRDWPVATDLFPLHWHLDSTAFRGTRQPRTDIRVTEAWSQGSQGEGVVVAVIDSLIQWDHPDLADNLYAIAEDQAGRLPGEVHGWDFSNRDTTCQADRCAVGDPDTRISDAELDLVRTDFQNTFTLSDGELLQTYRGLANRIANARPKWSQRQIANVIRGYIQGDIMAEFHGTWSSGVVAANPGSARGAVGVAPEAEILPVRVFGLGGEITVAALVEAIGYAAERGVDVINLSLGGLLPDRELTDQIMAVLDAHPDLVIVASAGNDSLDGVGFPAAIPAVISVGATTLEGERTVYSSYGGGLDVVAPGGDISQVPMYGILTTGGTWVPGFWQGIEQPIHPWSLGLDPLGHYVQVQGTSFSAPATTGTVALMLAANGDLTRAQVSQILQTTADYEGLALTQSEMNQYRLQAAVGLGTVVENQVLRPTGIFSFPEPISPEQYYFGGGLVNAAAAVEQARKLR
>NZ_CP021983|302064:372910|309769_310132_+|WP_080810739.1|DBSCAN-SWA
MDSLQEQVTVLTTKVDALHTALDQVNHRVSEILNTSQPTLNDGFTDSVMGNDGQSTVIAEGMFEHKDILMDTTYSKLDHSSTETQISPEVQVRRLTAQLTAAYNRIAALEEQLLALRSHH
>NZ_CP021983|302064:372910|364246_364717_+|WP_080814173.1|DBSCAN-SWA
MIAVSDTSPVNYLLLIDQIDLLPRLFQQIIIPDVVRKEMLDPLAPPALQQWITHPPSWLTVQTVSGVDTTLNALDPGEQAAITLAQTLPADLLIIDERLGRRVASDRGIPIIGTLGILDDAASQGLIELADAIARLQQTNFRISRRIIQTLLENRA
>NZ_CP021983|302064:372910|320173_321352_+|WP_080810727.1|DBSCAN-SWA
MVRSLSQGLGLLAIVASLSWGSSLRAQPSPLEPLPLPLDEVLGPQGGCDRSLWETPSERVRLIRAIGHSLRYLDTEAAASAYATYPVAGITHRRVRRSLVRFRQLLYQSRSFADFQQALQQEFMLYRSVGQDGAGTVLFTGYFQPTYAASRVPTADYRYPLYRRPADLEHWPTPHPTRLELEGSDGLQGSQGPLAGLELVWLRERLEAFLIHVQGSARLQLPNGEQLSVGYAGRTDYNYTSIGRELINDSVVAEADLSLPVLLDYFQRHPEALDHYLPRNRRFIFFQETAGGPPLGSLNVPVTAGRSIATDKALMPPGALALIRLPLPQLTADGYWRSQTVDRCVLDQDTGGAIQGAGRVDVFLGTGFVAGEQAGRLHGAGELYYLLLRESP
>NZ_CP021983|302064:372910|330400_331990_+|WP_080810716.1|DBSCAN-SWA
MRDLFAREALAHIPKLLTLQDRNPHSPTYGCFDRNFWQYKIIDFPSGMAQEFVWPLALAYDTDLAGNEFYRQPRLRDWVEAGIRYAASSAHRDGSCDDYFPFERASGAAAFSLLACLQSYRLLDLDDPKLLRFFEKRADWLAHHLESGRLTNHQALIALCLELASRLLGTDKWAAAIQNRLELVFSWQNPEGWFQEYEGCDPGYHTLTLGCLAWLYDLRPSSRLKDAIAKGVNLTAYFVHPDGSYGGEYTSRNTYNFFPHGFERIGRWFPPALSINDCILEGLAQGKGACYADDHIVGHHSWSYLLAWRDFVAERPPLKPPSMGRLWLPEARILIDQRADTRLYLALNKGGAFKVFRDERLLLSDTQFSLVVRQGRKVKNAVGHLVGPYRYHLGEDEVVVEGSLGWAKQKQMTPLNLIILRLVMLTVGRFFPNLIRKLLQTLLITGKTPAPFRFRRQLRWQQGRWQLRDELRADSWSQVMAVGIGPDQTSIYVVMSRTFQTGQLHPWLDLTPQVRQLSPGEPLIVERTL
>NZ_CP021983|302064:372910|355577_357359_+|WP_088428907.1|DBSCAN-SWA
MALIPFSAPVSTRDTTRTVGRDYQAVVLMAILSLLLLGGFGSRLAYLQLMQGDANRQLAENNRIRLLPKRPARGSLLDREGRLLAGNRLSHSVTLWPIALPKSQWPEVIRRLSTLLNIPTEDIQTKLEQAGYSSLEAVSIARGISPAQATALAEYSAELPAVRLEAEAVRSYPNGDLAAHVLGYTGELTQEELQERQDAGYRLGDVVGRMGAEAAFEADLRGEWGGQQVEIDSSGRVLRVLGDKPAISGEDVQLTLDIEIQKVAEAALGDQVGAIVALDPNNGAVLAMVSRPAFDPNIFSTQITQAQWQQLQSASYPFLNRALRAYPPASTFKIVTTSAALESGRYSPGTVLPTYPYVQVGGIQFWDWNKAGFGPLGFTGAMAMSSDTFFYQIAMGIKRAPLIEWTRRYGFGQKTGIEIGADESAGLVPDNAWKIENVGHEWTIGDTINMSIGQGFLQATPLQVAGMFAIAANGGYRVTPHLLHDQEDTEDWREPIGLSPTTIDILQKGLRRVITSGTARALNDANLPPIAGKTGTAEAPPGKSHAWFGGYIPAADPEILVVAFAEHSGGGGSAVTAPMVKQVLAAYVNGQSQ
>NZ_CP021983|302064:372910|304018_304216_-|WP_080810744.1|DBSCAN-SWA
MQASSTIIRTLVERALYIRRLTPDIEQGINCELSRLGYVSEVDFEALELLMCEMDAGRVKLVPSP
>NZ_CP021983|302064:372910|333051_333711_-|WP_088428893.1|DBSCAN-SWA
MTQATVTTDLYPDSDGQPMADNTKQYRWIVRLVSNLSNLLQDQTAFVAGDLLWYPVQVEAPPVPSQAPDAMVVLGRPDGDRGSYKQWEEDNIPPQVVFEIISPSNTATEISQKQAFYDRYGVLEMVFYDPDNLEFWGLTRQAPDDRPVLLTCLNLPWTSPTLGVKFDMFEDGLALFYPHGERFKDPEELYQERNQTQRKLNRAMEKLRQLGIDPSELEE
>NZ_CP021983|302064:372910|345141_345342_+|WP_080810699.1|DBSCAN-SWA
MGLEIGQKVKVTRLRDRVSRDLANRLGQSGVVSQYKMVDGSDVGVVVEFPDKFSSWFFEDELSSES
>NZ_CP021983|302064:372910|308402_309569_-|WP_088428885.1|DBSCAN-SWA
MKRRTFLQLVAATIGLGLSACGPASPEVEVRLLEGSIPARLIKRFKRQSQASATFTATPSLLSLFQDLRRWQRLPGEAVPRWQRIWNWVRFWQSESSPGNAPDWVSLGDYWLTAAVQEQLIQPLRSEHLPGWQRLSPAWQQLVRRDRNGQFAEDGAIWAVPYRWGSLIWIYDPRPFQRLGWQPSQWQDLWHPDLQRRFALPDHPRLVLGLALKALNQSANSPDVQAMAALSERLQTLQQQVQLYSSEHGLKALINGDLWLIVGWSTDLLPQLSQYRQFQAGIPQEGTILTADLWVRPTNAPLPLSAAAKQWIEFCLTPDHAAQLSLLSQGGSPLYAGQQRQALPSNLQEQPLIFPPADLYGRSEFLQPLSDSAQTAYDRLWQEMRSPG
>NZ_CP021983|302064:372910|305093_307811_+|WP_080810912.1|DBSCAN-SWA
MPVAIESLINADVAKPARYLGNELGAVHKPWHQAQVRWALTYPELYEVGASNLGHIILYSILNAQPRQLCDRAYLPAADLVTKLRQSGTPLFAVESRRHLLEFDILGFSLSYELGATNLLEMLDLAQIPLTWRERQQAGPWAVDSGSWPLIFAGGQTATSNPEPYADFLDFVALGDGEELLPEIALVVEEGKAAGLSRQDLLLDLAQVPGVYVPQFYDMAADGSVYPNRPDVPARVVRRVATPMPEYSIGLVPYVETVHDRLTVEIRRGCTRGCRFCQPGMLTRPARDVSPDKVVDTIEQGLRKTGYNEFSLLSLSCSDYLALPSLGVEVKNRLQQENISLSLPSQRVDRFDENIAHIIGGTRQTGLTFAPEAGTQRMRDIVNKGLTNEELLRGVKTAYEQGWDRVKLYFMIGLPGETDVDVLGIAETVRWLRQECRQPGRKALAVNLTISNFTPKPHTPFQWHAVSTAEFERKQALLKEEFRSLRGVKMNFTDVRISAMEDFVGRGDRRLAAVVHRAWQLGAGMDAWWESLDRAFAAWTQAIDEAGLSWKYRQREQDWNTLEAGEQAASLEAPLPWDHIDTGIDKAWLQADLRRALAAATVPDCSFEGCSHCGVCGPDFGHNVVVAPPPIPTFEGHFTPPQERVQRIRVRLGKQGNLTLLSHLDLMRLLDRAVRRAALPLAFTGGFHPGPRISAANALPLGATSAGEIVDFELTSPLAVAAFCQRLGAELPSELPIHEAAEVSLSAPSATKALAQAEYVITVAGADEVAIAPAEWAAWVAAVKAADRIIWDHRTKSGKLRQVNLCDRLDSLDPIAAPSPQDLPPQSHLSDPAHQALIRYGGSCRNDGSQLRPDHVVFMLEQVSQRPLRLCHIHRQRLILTPTPGDSTHAAEMVTASVTASLGTH
>NZ_CP021983|302064:372910|341809_342667_-|WP_080810706.1|DBSCAN-SWA
MQPLIYSYRSLVSGMAIAVTLAASNALKPRPPSPQSPPMKAVPWPPAMLHLGHSLAQEITPRLTSLAIAPPAALPLVLLPWRLRYPQHACDRLLQTLSHAYEPAALAAVWVVHEYLRQHLSQASLSSPAFAVPNITRGLDRAPPVAISAPIADLRHCLTTSAAYCRLSPLLQPLALALHYLDSSGGDYRLAMGRGLEANDTVATCGLIGLLATATAGLSIIPLSWRLAMTSSRSTISPLQRIWGCRETDLWQLAESLLASWAGVRMTQLPPDPDSNIPVMGMPYL
>NZ_CP021983|302064:372910|366379_367183_+|WP_080814143.1|DBSCAN-SWA
MREVLSEHLATFIRSLPEKREYARDDLLVPALKVAEDADKGLAVYDAPFGWGNQEARVALIGVTPGFTQMQILYRVVRRHLLLGASPEDACRLAKYEASFGGTMRGNLVRMLDELGVPELLEVASTADLFGSSSHLLHTTSAVRYPTFLHGQNYTGSQPRLVRSAFLMRYVRDVLAPELSRLHAAVFVPLGKSVAEALELLETEQRIPAGRTLHGFPHPSGANGHRARQFEKGKPAMRRRFEEILCGGASAGAVQQQHAADGAARRR
>NZ_CP021983|302064:372910|368587_369634_+|WP_080806623.1|transposase|DBSCAN-SWA
MGQQGFWDIEERQQKLEQKKAVLNRLNQLVPWETFRPILMQIREKPRKSQAGRNPTDVLLLFKMLVLQKLYNISDDELEYQVNDRLSFMQFLGLGLEDRVPDATTVWLFREQLQQHGLVEALFEQFGAYLQGAGYAAKDGQIVDATLIPVPKQRNTREENQTLKQGEVPVEWQETPHQLAQKDVDARWTKKNGTSHYGYKNHINSDAGFKLIRRYSVTDASVHDSQVLGELLDADNSGDGLWADSAYLSVLIVEVLKLIGFEPHINERAYRNRPLSEAQKTANRERSKTRARVEHIFGDVVTSMGGKVVRSIGLARAQTQLGLKNLVYNLKRFVCLETQRAASAELAR
>NZ_CP021983|302064:372910|363971_364250_+|WP_080814171.1|DBSCAN-SWA
MQITLDLPEELLQYFDQDHLSREILEALAVQAYQTEKITSAQVGRILGLPSRWAVDSFLKQHCAYLHYDETDLESDRETLRQLRANRANSAS
>NZ_CP021983|302064:372910|310195_311335_-|WP_088428887.1|DBSCAN-SWA
MNQVHTQVEAGQQWLDCCRWRRPYIAIVFGFTATGLIPGISAAGATPADRQQTALADAEFLYKGPHPRPRYALPPLMAGASPAIITRALVTSQHLPLRLFNAGLPHPLPAPAIDLQGPVASCLSGGEAMPMAQVRQLWQRGVHWGERLSREAQAGYLVLGECVVGGTTTALAVLLGLGIDATDRVNSSHPTCNHTQKLAVAQAGLSAWRQSPAFTEGALDPLALAAAVGDPMQVVVAAMAIAASRRVGVLLAGGTQMLAVYALLRAVAGYHGLAWTPERIAVGTTRWVATDGSGDTVGLAVQVADVPLIATQLSFERSHYPQLRAYEQGFVKEGVGAGGCAIAAHLHKNWQQPELLAAVEALWEQTLRINGMSGQGQID
>NZ_CP021983|302064:372910|312174_312879_-|WP_080810736.1|DBSCAN-SWA
MDPRYGPRDHHSESELIRSAPFFQGIPDAAVQQATAQVVTRRHPANQVLLLENDWGSSVYFILDGWVKIRTYNLDGKEVTLNILGKGEVFGEMAPLDEVPRSTDVITLVPTMIGNMPANDFVHLIHTEPIAGIRLAQLMARRLRQVNRRLRLRESDSMSRVADIILFLADGQGQEGDNGVEIPNLPHRELSSLSGLARETVTRVLSKLEKKTLIVRERDIMRIPDIDALERLLV
>NZ_CP021983|302064:372910|361246_362395_+|WP_080814165.1|DBSCAN-SWA
MSSSAYEGFNEESFFDRVEAQFVKKAPNLSQTLNIAVIGKVSAGKSSLINALLKLSRRQALEIAKVGATSGVTTDLTILKLDEKVHLVDSPGLDDVRTENSELTKKFLKHIDVGIFVVTGSSDSSQKKNLDDLRQHCDAIFVVLNKIDEWDDLDPSVLEDIIQQWKTDLEVEKIYPTCAKGYDPKSRLPTMDIRGVAKLRNDIGDFLEKKGKDLLLARHMAQKQSHAVKIIAVALAAVAGEAFIPGSAIYITATQGAAIASLSYLYTGEILSAESTLSILPKFVAETAGSNLFLFVKSFLPPTGIVDVAAAGVAVVITLALLATVNYLLSNGEELEQEELLRSKFRTYHQQAKDTFKELALTDVRDLPSWTKLVNKFLGSRQ
>NZ_CP021983|302064:372910|351856_352759_-|WP_080814155.1|DBSCAN-SWA
MSKAPGGLHRGSIWLRQRLRRLLGPIALLGPAGLWLGLLLVIPTLLILDISLVPGLRPGEPAAGYGLDNYLQILQPVYLRVIARSLYFAAGTTSICLLLGFPVAYWLALKAPRRWRNLLLVAFVLPLWTSSLLRAYAWISILRPTGLLNLVLAHLGLPTQAWLHTTAAVFIGLSYSFLPYMVLILYASLEKLDTRLLEAAADLGATPLQGFWQVTVPQTLAGIAAGCLLVFITSVGDFVVPTLLGGASSMNIARLIYNQFLGPTRNWGFGSALSMVMILAVSVAIALLLRYGDRSSVSET
>NZ_CP021983|302064:372910|319906_320161_+|WP_080810730.1|DBSCAN-SWA
MPRTPSEYIIHLLFDGGHHQEVRFSSIQEFQKWYSGELMPKANSDDFISVPVPKINPGEYMVIRPSRLVSIRVEPVFSSSVERF
>NZ_CP021983|302064:372910|326660_327644_-|WP_080810722.1|DBSCAN-SWA
MGKINPYRLKISQLRALVTIADSGSFSDAALQLNLSQSAVSHAIATLEEELGVVLLSRSRQGAILTPIGAQITEEARRVLQGLEHLCRQAQAARGLQAGQVRIAGFRSVATHLLPVVIQQFRQQYPGLGITINEYQNFQQVEEDLRQGRADVGFTYLPTQPEFEAWELLHDRYVVLLPPAPEPPPQPFTWPHLSTYPLILGPAHDSDRTYVDRHLRRCGVTVKPTYEVKEDSTILGMVKRGLGATIMARLAAEPIPSGIRVAEVPVPLERVIGLIVLKDALLPPAVYAFIDIFKTVVQQVPLDMIDSASPVVSLPFPDQGNSSVPPQ
>NZ_CP021983|302064:372910|367226_368399_-|WP_080809504.1|transposase|DBSCAN-SWA
MPSSTQLYDQLLHYLRQYSHYRDLRHIKALSWMVTALICSGELSPPAWESYVISRANKAQSFERRWHRFFGNRLVEINQLYLPLVLLTLRQWEGKRLYLALDTTVLWNQYCMIHLSVVCCGRAVPLLWRVLEHGSATVAFEEYRPLLRRARWLLRQYPNLMLLADRGFANHDLMSWLQASSWHYCLRVPCDVLLHGPRRYPTEVRYLWPPKGEAIFYRNVRLWQDGSHQCNIVLATLKGVKEPWAVITDEPPTLQTLWRYALRFRVEELFLDSKSGAFEIEDSRIRSAVALERLYLVAAIALLYGTTTGMAVQIEGLRQQVDPHWRRGLSYLKIGLRWLKGVVHKGRQLLEPIALLVRDPEPCFASKKAEHDYYDQIWFSRIRSLSCRLE
>NZ_CP021983|302064:372910|342784_343693_+|WP_088428901.1|DBSCAN-SWA
MIRACSTDVRWPQAGRKPSHHCHASIDRRQIWPMLLATLVGVAGGDLFTAQASQAIEMAPAGSVTGEPQLTALGQNKDLSLRLARITRPTLQLGSTGETVQELQTVLLFLGYYSGPVDGQYLDATEEAVRQFQAAAGLNPDGVVGPATWNQLFPSPPRQANPPSTTTSASTVPETSSVTPVAPAEATNPTAASEASSTAAEPTVAQTTSEDSEEVAEPAGSEKPPESSGQGPVELPVLRSGLAGPAVARLQERLRVLGVYAGVIDGIFGRQTEAAVRQIQRRYQLQVDGIVGPATWQALLAN
>NZ_CP021983|302064:372910|359817_360621_+|WP_080814143.1|DBSCAN-SWA
MREVLSEHLATFIRSLPEKREYARDDLLVPALKVAEDADKGLAVYDAPFGWGNQEARVALIGVTPGFTQMQILYRVVRRHLLLGASPEDACRLAKYEASFGGTMRGNLVRMLDELGVPELLEVASTADLFGSSSHLLHTTSAVRYPTFLHGQNYTGSQPRLVRSAFLMRYVRDVLAPELSRLHAAVFVPLGKSVAEALELLETEQRIPAGRTLHGFPHPSGANGHRARQFEKGKPAMRRRFEEILCGGASAGAVQQQHAADGAARRR
>NZ_CP021983|302064:372910|371863_372910_+|WP_080806623.1|transposase|DBSCAN-SWA
MGQQGFWDIEERQQKLEQKKAVLNRLNQLVPWETFRPILMQIREKPRKSQAGRNPTDVLLLFKMLVLQKLYNISDDELEYQVNDRLSFMQFLGLGLEDRVPDATTVWLFREQLQQHGLVEALFEQFGAYLQGAGYAAKDGQIVDATLIPVPKQRNTREENQTLKQGEVPVEWQETPHQLAQKDVDARWTKKNGTSHYGYKNHINSDAGFKLIRRYSVTDASVHDSQVLGELLDADNSGDGLWADSAYLSVLIVEVLKLIGFEPHINERAYRNRPLSEAQKTANRERSKTRARVEHIFGDVVTSMGGKVVRSIGLARAQTQLGLKNLVYNLKRFVCLETQRAASAELAR
>NZ_CP021983|302064:372910|321467_322577_+|WP_080810726.1|DBSCAN-SWA
MESSISLKHHVIQNRIRQVGINENYWYPVAWSHQLPVGQILAITIWGHSIAVYRDVQGQVHALENACPHKGVELHLGEVQGDCLVCPYHGWQFNPQGQCVAIPYFPAEQKLPRAQARRYPAADQYGMIWVFPGNSQQASSQAIPAIPEYDDPNCLAIPITGIFAAHFSICNENTMDVFHGFLHKNLQGWFNPVLLDLQEGDDYVNARYQVSYKGFLSQFLGLGSDNAGVSTRIVSIHYQYPHYHSTLEGVSSLYLMRLPVSPTQTRSFSWLFLPKIRLPKWLLRPLKPTVVPLIRRLLFMPFLEQDMAMMASEQRTYSRSPNRQYVEVNPAIIALQRVIMKQYELYQQQMRWPKAGRRPSHPSGLPLPN
>NZ_CP021983|302064:372910|338080_338848_-|WP_088428899.1|DBSCAN-SWA
MKKFVYWLMGERAGRVVVISWNWLWGRPIEADSQGAVNAAEESLRSMQTSVQQLSQAVSTQAASYERAKKKYEIKVKELQDAEHEAVLAQQLGNIEAARLAMTRALQIERFLPQLEQRVRQVEALVNQSKEKLDRERMRLEAYKFEFQHMKDMAEINEALRLVAETNDSLNIQSSQSQFEAAKAVVEDRSFYEEAYAELSEDPQDQLQADIEKMTLNDQVEKRLKKLRNSELTESPQRTNAMNDKPFIDPESSSQ
>NZ_CP021983|302064:372910|360664_360955_+|WP_080814163.1|DBSCAN-SWA
MELVFALLVVAILASLPAAVLVVGVFTAHARPDSPLLRHWRLVATVGFSAWALLTLVSHLSDAPGYTGIGSGLGILLLVFVFIARSRASTLSSGTA
>NZ_CP021983|302064:372910|357488_358322_+|WP_080814160.1|DBSCAN-SWA
MSPEPPELIIEAGRTEAQYWRDLWRYRELFYFLAWRDILVRYKQTAVGVAWALLRPFLTMVVFTVVFGRLAKLPTEGDAPYPILVFAAMLPWQFFANALTECSNSLIQNANLIAKVYFPRLVVPTSAVIVSFVDFLISGIILLGLMAWYAAVPSWRIITLPGFIAIAFAAAMGAGLWLAALNVQYRDFRYVVPFLVQFGLYISPVGFSSSIVPQQWRLLYSLNPMVGVIDGFRWAIIGGDVQLYWPGFLLSLLLVAALLFSGILYFRHMERTFADII
>NZ_CP021983|302064:372910|365691_366228_+|WP_080814176.1|DBSCAN-SWA
MEPSISAKAKINFKTGEVEFEGSEQFVENQLNNIDTIAEYMALLISNNSTDEVDEIEQEEIAAVAEEEEEKLVTVGEQDLHVPDTFGEWFHGFKDDANDLDKALITAFYVQKQAPDNDFKTSEVNQSLQDHGIKLSNPSSSLKRLASKKLLFQTRKVGKLKYMRVSADGVKHLKTLRR
>NZ_CP021983|302064:372910|318826_319789_+|WP_080810732.1|DBSCAN-SWA
MIHATLHQLKVFEATARHGSFTRAAEELFLTQPTVSIQVKQLTKAVGLPLFEQIGKRLYLTQAGQKLLETCQEIFAGLDQFEMSVADLKGLKQGQLKLAVITTAKYFVPRLLGPFCQRYPGVDISLKVTNHQHIQERMANNEDDLYIISQPPEQPDLKIYPFLENPLVVIAPKNHPLVGKSNVAIQALNDEPFIMREPGSGTRHAVQSLFAKHKIDVRVRLELGSNEAIKQAIAGGLGISVLSLHTIISEGTSGEFAILDIDHFPIERQWYVAHLAGKQLSVVADTFLTYLQTESHTLAEKFLPGIKPAKARQGNLSKAS
>NZ_CP021983|302064:372910|329365_330373_+|WP_080810718.1|DBSCAN-SWA
MKLIIQIPCYNEEATLPITLGDLPRQVPGIDDVEWLIINDGSTDRTVEVAREWGVDHIVDFDHNRGLAKAFMAGLEASLKAGADIIVNTDADNQYYAGDIPRLVEPILAGQAEIVIGARPIQRIRHFSPVKKVLQKLGSWAVRMASRTSVADAPSGFRAISRQAALQLNVFNEYTYTLETIIQAGQRGMAVISVPVHTNDYLRPSRLVKSIVSYVQRSLLTILRIFVTYRPLQFFTILGAIPFSAGFLLGLRWLYFFLIVGSDRTRVPSLILTAILILIGVQLWVFGLVADLLSVNRKLLEDIQLRLRRNDIETERQRRLLQQQSSSLKVGRSGR
>NZ_CP021983|302064:372910|328201_328918_+|WP_080810720.1|DBSCAN-SWA
MTDSLLTAAVLFGATLISSTFGFGSALFAMPLLTLVVGIETATPLFGLVGPTIAISIAIMSWQEIQLTVTSRLIAATLCGLPIGVWLIRTLPGDWLADGLGVALIGFGLYRLGRVTLPRLIHPGWAYPFGFVAGILAGAYNTNGPPVVVYGNLCRWPPERFRATLQGYFLPTGLAILASHGLGGLWSVHIFQLYGLSLPLVFLAVWMGHWLNRRLPTEQFERFLSGLLLVLGSLMIWR
>NZ_CP021983|302064:372910|352830_353994_-|WP_088428905.1|DBSCAN-SWA
MPRRPRLSFHGSRRLSSTTRRRFLYGSAATVASLALANCRQNITNVQSEAPPSATPTGTGNGNDGKLYVYTWANYTDQALMDQFTEATGIEVVVNTYESNEAMLAKLQAGGGSNYSIVYPSDYMVIKMRNLELLTALDQDRLAGTNALLAKWQDPVYDRGNRYSVPFCWGTTGLLFNREALPTVPQDWEYLWQQQDVLSRRLTLLEDVRETLGAVLKSLGYSYNSTDSAELEAAFNRLMELKPHIASFKTSGFETELLGGDLLMVMSYSSDAIAATLEDERFEYIVPASGSSVWTDTMAIPTTAPNVDAAYEWINFILQPQVCKDAVERLFFATANQSAYDQLSPELKNNQDLFPPAEVVDKCEGIAPLPNEVLETYDRYWTEITSA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_088428877.1|302064_302886_-|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_080810747.1|302924_303212_-|protease	ATP-dependent Clp protease adapter ClpS	NA	NA	NA	NA
WP_088428879.1|303433_303826_+	hypothetical protein	NA	NA	NA	NA
WP_080810744.1|304018_304216_-	hypothetical protein	NA	NA	NA	NA
WP_088428881.1|304547_304874_+	anti-sigma factor antagonist	NA	NA	NA	NA
WP_080810912.1|305093_307811_+	B12-binding domain-containing radical SAM protein	NA	NA	NA	NA
WP_088428883.1|307824_308406_+	hypothetical protein	NA	NA	NA	NA
WP_088428885.1|308402_309569_-	polyamine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_080810739.1|309769_310132_+	hypothetical protein	NA	NA	NA	NA
WP_088428887.1|310195_311335_-	TIGR00303 family protein	NA	NA	NA	NA
WP_088428889.1|311352_312168_-	DUF2232 domain-containing protein	NA	NA	NA	NA
WP_080810736.1|312174_312879_-	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_088428891.1|313410_318576_+	hypothetical protein	NA	NA	NA	NA
WP_080810732.1|318826_319789_+	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	7.7e-16	24.2
WP_080810730.1|319906_320161_+	hypothetical protein	NA	NA	NA	NA
WP_080810727.1|320173_321352_+	murein transglycosylase	NA	NA	NA	NA
WP_080810726.1|321467_322577_+	aromatic ring-hydroxylating dioxygenase subunit alpha	A0A076FFT9	Aureococcus_anophage	1.4e-08	24.4
WP_080810724.1|322743_323874_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_080810722.1|326660_327644_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_080810720.1|328201_328918_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
328503:328518	attL	NA	NA	NA	NA
WP_080810718.1|329365_330373_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_080810716.1|330400_331990_+	hypothetical protein	NA	NA	NA	NA
WP_080810715.1|331986_332964_+	UPF0104 family protein	NA	NA	NA	NA
WP_088428893.1|333051_333711_-	hypothetical protein	NA	NA	NA	NA
WP_088428895.1|334019_336215_+	peptidase S8	NA	NA	NA	NA
WP_088428897.1|336468_337908_-	receptor ligand binding family protein	NA	NA	NA	NA
WP_088428899.1|338080_338848_-	hypothetical protein	NA	NA	NA	NA
WP_080810708.1|338944_341464_-	HDIG domain-containing protein	NA	NA	NA	NA
WP_080810706.1|341809_342667_-	hypothetical protein	NA	NA	NA	NA
WP_088428901.1|342784_343693_+	peptidoglycan-binding protein	A0A023ZWN3	Mycobacterium_phage	5.8e-05	51.7
WP_080810703.1|343739_344006_-	hypothetical protein	NA	NA	NA	NA
WP_080810701.1|344250_345018_-	imidazole glycerol phosphate synthase subunit HisF	NA	NA	NA	NA
WP_080810699.1|345141_345342_+	DUF2862 domain-containing protein	NA	NA	NA	NA
WP_080810693.1|345366_346461_+	arsenic-transporting ATPase	NA	NA	NA	NA
WP_080810691.1|346583_347579_+	chlorophyll synthase ChlG	NA	NA	NA	NA
WP_088428903.1|350117_350321_+	hypothetical protein	NA	NA	NA	NA
WP_080814153.1|350394_350817_-	TerB family tellurite resistance protein	NA	NA	NA	NA
WP_080814178.1|350922_351663_-	ABC transporter permease	NA	NA	NA	NA
WP_080814155.1|351856_352759_-	ABC transporter permease	NA	NA	NA	NA
WP_088428905.1|352830_353994_-	spermidine/putrescine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_080814157.1|354104_355238_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.7e-28	35.1
WP_088428907.1|355577_357359_+	penicillin-binding protein 2	NA	NA	NA	NA
WP_080814160.1|357488_358322_+	ABC transporter permease	NA	NA	NA	NA
WP_080814162.1|358584_359550_-|integrase	integron integrase	A0A1P8DJJ6	Virus_Rctr41k	1.6e-61	43.2
WP_080814143.1|359817_360621_+	hypothetical protein	NA	NA	NA	NA
359987:360002	attR	NA	NA	NA	NA
WP_080814163.1|360664_360955_+	hypothetical protein	NA	NA	NA	NA
WP_080814165.1|361246_362395_+	GTP-binding protein	NA	NA	NA	NA
WP_080814167.1|362477_363332_+	hypothetical protein	A0A1B1IT49	uncultured_Mediterranean_phage	1.4e-08	48.5
WP_080814169.1|363349_363856_+	YbjN domain-containing protein	NA	NA	NA	NA
WP_080814171.1|363971_364250_+	hypothetical protein	NA	NA	NA	NA
WP_080814173.1|364246_364717_+	DUF3368 domain-containing protein	NA	NA	NA	NA
WP_080814175.1|364910_365687_+	DUF4145 domain-containing protein	NA	NA	NA	NA
WP_080814176.1|365691_366228_+	hypothetical protein	NA	NA	NA	NA
WP_080814143.1|366379_367183_+	hypothetical protein	NA	NA	NA	NA
WP_080809504.1|367226_368399_-|transposase	transposase	NA	NA	NA	NA
WP_080806623.1|368587_369634_+|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
WP_088428909.1|369845_371048_+	VWA domain-containing protein	NA	NA	NA	NA
WP_088431479.1|371445_371808_+	DUF4157 domain-containing protein	NA	NA	NA	NA
WP_080806623.1|371863_372910_+|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP021983|782611:838302|DBSCAN-SWA
CATGCTTTTCTGGTTGCTTCTCCTGGGCATTTTTACCTACGTTGTGGTCAAGCGCAGCGTGGCTAATGTCACTCGCACGCCGACGTGGTTACTGTGGCTGGTGATGATGTTGCCTGCCTTTAGCTTGGTGATCTGGGCTTCGGTGCAGGGCAGCGAAGAGCCTTTTCCCACGGTGCTGCTGATTAGTTTGTTTGTCCTATGTCCCCTACTGTACTGGTGGTTAATTCAGTGGGGCCGCCCGCAGCCTGCTGCTCAGGTCAAGGCTAGGCCCTCTGAGCGCACAACACTGCCATCATCAGAGGAATCAAAATCTACCCTACGCCCCATGAACCGGGATGAAGAAGCGACGCTGAAGCATTGCTTCCCCTGGACGGTTTATTACCTACAAAACATCGAATATCGTCCCCAGGCCATGATCTGTCGGGGACAATTGCGGGCAACCCCAACGGTGGCCTACGAGACGGTGCGAGAGAATGTCCACTCTCGCTTTGGGGATCGGTTTCTGTTGGTATTTCAAGAGGGATTTAATGGTAAGCCGTTCTTCGCCCTAGTGCCTAATCCCCGCACTCAGACCCAGCAAATGTCTACCCAACCACCATTGACCCGGCCGGGATTGGCCCTGGGTTTATTTTTGACGACGGTGTTCACCACCACCGGGGTGGGCGCGATCATTGCCGGGGTGTCTGAAGAGACGCTGCAAGCAGACCCGGCCTCGATTTTGCGGGGATTGCCCTATGCCTTAGCCCTAATGGCCATTTTAGGGATCCACGAATTGGGACATTATCTGATGGCGCGGCGGTATCAGATTCAGACGACGTTGCCTTATTTCATTCCGGTGCCCTTCTTTCTAGGGACCTTCGGGGCATTTATTCAGATGCGCTCGCCGGTGCCTAACCGCCGCGCCCTGTTTGATGTGGGCATCGCTGGTCCTATGGCTGGCCTAGTCATTACCTTGCCTGTGCTGCTCCTGGGGTTACGGCTGTCAACTGTGGTGCCGTTAGCGGAGGAAGCCAGCTTACTTAATTTTGAGGCCCTCGACCCCAGTGCTTCGGTCATGGTAGCGTTGCTGAGTAAACTAGCCTTAGGCAGCCGCCTGACCCTAGAACATGCCATTCATTTGCATCCCATGGCGGTGGCTGGCTGTTTGGGGTTAGTGGTGACGGCTCTCAATCTGATGCCGGTGGGGCAACTGGATGGCGGGCACATTGTCCATGCCATGTATGGTCAACGTACTGGGGCTATTATTGGTCAAGTGTCACGCCTACTCGTGCTGGCGCTGGCAGTGGTGCATCCGGAATTGCTAATTTGGGCGATTCTGTTGTTTTTTATTCCGGCAGTGGATGAGCCCGCTCTGAATGATGTGAGTGAGTTGGATAATCAACGTGACCTCTGGGGTCTAATGTCCCTGGTTGTGCTGGTGATGATTGTCTTACCGGCTCCTTCCCCGCTGCTGTCGCTACTGTTTTGAGTCAGTAGTGGGTTGCTAGAGTATGTGGAAGTCCCTGTGCTCTCTTGTCTGGTGAGGACAAATCCATGGCCCACGATGTCACTCAGTGGCTAGCTGAAATCCGCACCCTGCAGCAGCAACTGGCCCAAGTACGTCAGGAGCGCGATGATGCCTATGCCAGTGCCGCTACCTGGCGGCGGCTGTATGAAACTGAGGCGCGACAGCGACGACAGGATACGCAGGCGTTGCGATCGCAGCTGCAGTCTCTGCAGGAAACCCTAACCCAGCTCAATGGTCAGGGGACTGATTTTCTAGAGCACGCGGTGGATCTGTCCCAGCAACAGATCTCGGACATCAATACTATCGACGAGTTGCGATCGCACCTAACGGCTGTCCTGCAGCGTTGCCAACAACTGCGTCAAGCCCTAGAATGCGAACGGCACCAACACGGACAAACGCGCCAAGCTCTAACCACCGCCTTGGGAGACACCTTCGATCGGGTCAAAGGGTGGTCATCTAGTTAAAACCCCATAACCCCAGCCAAGGTCTCTAGATCAGCCGGCAACCCTCCCTTCACCTGATTTTGGCTGTGCTTAATTGCCGTGTCCGGATCTTTGAGCCCATTCCCCGTGAGCACACAGACTACCGTTGCCCCAGCAGGCACCCGATCCTTAACCTTCAATAAGCCAGCCACAGAGGCGGCACTGGCCGGTTCACAGAAAATCCCCTCTTCTGCTGCCAGCAATCGGTAGGCTGCCAAAATCTCTTCATCAGTGACGGCTGAAAACTCGCCCTGACTCGCTTCCTGAACTGCCCTGGCCCGATCACGGTTAGCCGGATTGCCAATGCGAATAGCCGTAGCCACCGTTTCTGGATGAGTTACCGTGTGGTTCAGCACCATAGGTGCCGCCCCCGCTGCCTGAAATCCCATCATCCGAGGCAAGCGCTGGCACCGTTCCTGCTGGTGGTACTCACAGAATCCCATCCAATAGGCCGTGATGTTTCCAGCATTCCCCACGGGGATGCATAGCCAATCCGGAGCATCTCCCAGAACGTCCACTACCTCAAAAGCCGCCGTCTTCTGCCCCTCCAAGCGAAAGGGATTGATGGAATTTACCAAGGTGACTGGATAGTGCTCAGCCAATTGACGCACCATGGTTAAGGCCTGATCAAAATTGCCCTGAATGGCCAAAACCTCAGCCCCATAGAGTAGGGCTTGGGCCAACTTACCCATGGCCACATAGCCATCCGGGATGATCACAAACGCCCTGAGGCCACCGCGACGAGCATAGGCTGCCGCCGCCGCTGAGGTATTGCCAGTGCTGGCACAAATGACGGCTTCAGCCCCCATTTCCTTAGCCTTAGAGATGGCCAGGGTCATGCCTCGATCTTTGAAGCTGCCGGTTGGGTTTAAGCCGTCATACTTGACGAACACCTGCACCGAGCGACCGACACGCTCAGCAATCGCTGGCACCCTAATCAGCGGGGTATTACCTTCACACAGACTCACAATTGGGGTGGCATCTGTCACCGGCAGGAAAGGACGATATGTTTCGATCAACCCTGGCCAAGGACGTGTACCAATGGCAGGATAGTCAGCCTGGGGACTCTCAGAGATAGGGCTATTTAAGCTCAGGGTCACGATAGATCACTTGAACCGCGGCATCAGCAAGATTCGGTCTATCGTCGACACTGCTCCAGGTGAACCCAGGGACCTTAGTGACGTTTGAGCAATAGACCGTGTCCTTCAGTCTAACGTGTGCTCCGAACAGACCTACAGAGAAAATCCCTTGATCCACTTCAGAAACTGCCACAATTCCATCTAGACCACTGAGTTAGTCTCAATACCATCTGTAGCAGCTGATTTAGTTTAGAATCCATGGCATCGCTTCATCCATCTATCTGTCGATGCAATTTCAGGAGTTGGATGGGATGCTACTTAAGCATTCACCTAAATCGCCTGACGCCACGCTTAAATTGTGGAGCACCCGATGAGTATGCTGTCGGCCCCCTCTCGCTGCGAGCCCCCCTATGCCCTCCTAGAGCAATCCAGACGGCCCCCAGAAGCGTCCTTCCCCCATGCCATTGCTCCTACAAACTGGATTGCAGATCAGACATCTCCCTACTCCCTAGCTCACCAAGTCGAGTTACAGCACCTACAGGCAGAGGCCGATGCACTCTTACGGCAGCTGCAAGCCATTCAGCAAGCCCGAGGGACCTCACCCACTAGTACTCTGCAGCAGAAATAACGCCTCTATTGATCGTGGCATCCATGGGAAGGGTATCCCGTTTGAATAGGAGCACCTGTGTTGCAGCCATTGCCTTAATCCTACTCAGTTGTGTTCCCATTAGCACAGGCAGCTACCAAGAGGCATAGGAAGTAAGCCTCCTGTCGTTCCACCCGAGTTCCTGTGCCGCAGCGATGAGGTGATGATTTATCTGCTCATCTCGCTCACTAGCCCAAAAACAGGTGATAGGCGGGGTTTTGGTTCTCGCCCCAGTAGGGATAGCCCAGGGTGTCTAAGAAGGCTTGCCAGTCGTCCATATCTTGGGGGGGCACCTGAATCCCCGCCACGATGCGGCCGTAGTCGGAGCCATTATTGCGATAGTGGAACAGGCTGATGTTCCAGTTGGGGCTCATGGCGGTGACAAACTTCATCAGGGCTCCAGGCCGCTCCGGAAACTCGAAACGATAGAGTAATTCATCCTGGGCCAGGGGCGATTTACCTCCCACCATGTGGCGCAGGTGCATCTTGGCCAGTTCGTTATCGGTGAGATCCAGGGTAGTGAAGCCCTGAGACTCGAACTTGGCGGCAATTTCGGCGGCATCGACCCGGTCGCGGATTTGCAGGCCGACGAAAATGTGGGCTTCTTCTTGGTGGGCGATGCGGTAGTTGAACTCGGTCAGGTTGCGTTTGCCGATACACTCACAGAATTGGCGCAGACTGCCGGGTCGCTCGGGAATGGTGACGGCGAAGATGGCCTCTCGCCGCTCCCCTAACTCGGCCCGCTCGGCCACAAACCGCAGCCGATCGAAGTTCATGTTGGCACCACAGGCGACGGCTACCAGAGTCTGTCCCTGAATGCCCTGCTGTTCTGCATAGGCCTTGGCGCCGGCCACAGCTAGGGCGCCGGCCGGTTCCAAAATAGAGCGGGTGTCTTCGAAGACATCTTTGATGGCGGCACAGGTGTCGTCAGTGTCTACCCGAATGATGCGGTCGACATAGCGCTGGCAGAGGCGGAAGGTCTCGGCCCCGACTTGCCGCACCGCCACTCCATCGGCAAACAGGCCGACTTGCTCTAGCCGCACCCGCTGTCCAGCCTGCAGGGACTGGTACATGGCGTCGGCATCGGTGGGTTCGACGCCGATGATCTGGATCTCTGGCCTTAGCCGCTTGACATAGGCGGCAATGCCGGCAATCAGGCCACCGCCACCGATGGCCACGAAGATGGCATGAATCGGTTGCTGATATTGGCGCAGGATTTCCATGGCGATGGTGCCCTGGCCCGCAATCACATCAGGATCATCGAAGGGATGGATGAAGGTAAGGCCCTTTTCTCGCTCCAGTTGGCGGGCATGGCTATAGGCATCGTCGTAGGTTTCGCCGTGGAGCACCACGTCGCCGCCGCGGGCTTTGACGGCGTCAATCTTCACTTGGGGAGTGGTGGTGGGCATGACGATGATGGCCCGACTGCCCAGATGACGAGCTCCCAAGGCTACCCCCTGGGCATGGTTGCCTGCCGACGAGGCAATCACGCCCTTGGCTAGGCTTTCTGGGGGTAAATGGGCCATTTTGTTATAGGCTCCCCGCAGCTTGAAGGAAAACACCGACTGCACGTCTTCCCGCTTCAGCAGTACCTGGTTCTGCAGTCGGGTGGATAGATTAGGGGCGACTTCCAAGGGGCTCTCTTGGGCCACGTCATAGACCCGAGCCAGGAGGATGCGTTCTAGATAACCGTCGCTGGACATGGAGGGGAGGGTAATGGGCGACATTCTCACGCTACCACTGCCTGGGTATTTCCAGGACCATGGGAGAATCTGAAGCAAGTTCGTGGGGGGTAGTCTGTAGGGGCGATGCAGGTCATCGGCATTGACTTAGGGGGCACGGCCATTAAGGCAGGGCGCTTTAACCAGGCGGGAGACTGTCTGCAATCGCTGACTATGCCCACGGCGGCACCGCCGCACCCGGATCAGGTCTTGGCCCAGATGGCCGCTGCGATCGCATCCCTCGATCCTCACCACCAGGTGCACGCCATCGGGGTCGGCACGCCGGGGCCAGCCGATGCCGCCGGCCGGGTAGCCCGCATTGCCATCAACCTAGCCGGCTGGATCGAGGTGCCCGTGGCCGACTACTTAGAGGCCAAGGGTGGCCGCCCCACGGTGGTGGCCAACGACGCCAACTGTGCCTGCCTGGGGGAGGCCTGGCTGGGGGCGGGACGACCGTTTCGCGATATCGTCATGCTGACCCTGGGCACTGGCGTCGGCGGGGCGGTAATGCTGAATGGTCAGCTGTTTTTAGGGCGCCATGGGGCCGCCGCCGAACCCGGCTTAGTCACCCTAAACCCTGAGGGCCCCGCCTGCAATAGCGGCAATCGCGGCTCCCTAGAGCAATACTGCTCGGTGCAGGCGGTGCGGCGACAAACCGGCCAAGAGCCCAGTCACTTGGCAGCTCGAGCCCGGGCCGGAGATGCCGATGCGATCGCATTTTGGCAACAGTATGGCCGCTGGCTGGGGGCCGGTTTAGCCAGTTCTGTCTACCTACTCACCCCGGAAGCCATCATTTTGGGCGGCGGCATCAGTGCCAGTGCCGACCTGTTTCTGCCCAGCACCCTAACCGAGCTGCAGCAACGGGTGATGGCCACTTCCTACGACAATCTACAGATCTGTATCGCCCAACTAGGCAGCCAGGCTGGCCGGGTCGGGGCCGCCAAATTGGCCCTACAGCAGTTGGGGCTAGGCAGAGACTAGGACAGGGCGGCAGCCGTGAACTACACCGTGCCCTACTACCTACTCGGGATATGGGCCCGAAATCGGCTGGCCACACACCCGAGTCAAGACCCAGTCCCGCATCAAGTCATTGACTAACTCTGGCCGCTCATCGTGGGGGCAGTGGCCTGCTGGTAAATAATGCTCCGTCAGCTGCGGATAATACTGGCGAAAGCGGGCGCCCCGCTGCCGCGTATCCATCCAGGGATCTCCCTCGCCCCAGAGCGTCAGCAAGGGGGGGCAGAGTCGAGTTAGCAGGACATCCACCGGTTCTCCCCGAGGCGCCTTAAACACCGAGGCAAATACCCTAGCCGCGCCAGCGTCACAAGCGGGGCGATAGATCGCCTCTACCAGATCATCAGTCACCGCCGTGGCATCTAGATACACCTTCATCAAGGTCTTGCGAATGGTGGCCCGCCGCCGTACATACTGAAACAACAGCCAACTGGGCAGCGGCTGCAGCATGACACTGCGTAGGGCCTTAGCCAGGGCACCACCAATGCTAGATTTAGCCGTTGAGACCTGAGCATCCGAGAAGGGGCCAGCACTGTTCAGTAGCACCAGCCCGGCGGCAGCCTCTGGATGATTAGCGGCGACACAGAGACTGGCATAGCCCCCCAAGGAGTTACCGACCAACACCACTGGTTGCCCAATGACTTGGGTAATAAAGTCGTGCAATTGGGCCTGCCAGAGATCACCGCTGTACTGCCAGGGGGGTTTAGCCGAGCGGCCGAACCCCACCAAATCGATGGCCCACACCTGAAACTGATGTTGGAGATCGGCCAGGTTCTTCCGCCAGTGGTCGGTAGACGCCCCAAATCCATGTACCAATAGCAACGGCGGGCGATCGCCTGGGGGGGGTCCGGCTTGAACGTAATAGACTGGCTGTCCTCGCCAGGTCCAGTGCTGGCCAACACCAGAGGAATCAATGGGATTACGGTCAGAAATCGTCACCATCGCGGTTAACCATCGTGAATAAACCATGTTCGAGTCCAGCCCCGAAGGGTTGTCTAGGAAAGACTGCCAGGTCTGGAGCGGAGCTGGGTACCTCCCTATTCCAGACCAAACTAGCCATAAGCCCTTTAATCTCAGCACTTTTCCCTAGCAAGTCCTTCAGGCTGTTTTGATGGTAGCGAATCCCCTCTTAAATCCAGGGAACTAGCTTCCAGGCTGCTATCGGCAGCTGACAAAACTTGATAGGGTAACACTGCTTTCGTGTCGCATTCGTATCAGGTGGTCCAGTGCTATGGCTGCTCTCGCCCGTTCCCACAAAATTCCTCGCCGCCGCCGTACCAAATGGCTCTGGTTTGAGCGCCTGATGGCTCTGATTGCCCTAGTCAACTTAGCCCTAGTCCTATTCGACCTCAGCTATATCCGCTTTCGAGACTTTTATTTGAAGTTCGTGCCAGAGCTCACTGAGTGGTACGGCGCCACCTATAAGGGCATTCAGCCAGAGCGATCCACCGTGACCTACCTAGAGACCGTGGATCGCCTCGAGGAGCAAGTGGCCCAAACCGGGCTGCAATCACGTCAGGCAACTATCTTGTTGAACCAGCTGCAACAGCAGAGCATCGAGCTAATCGATGAGAACCCCTTTCAGGTGGCCAATAAATCCGGCACCCTAGAGCGGATCAAAAACATGATGCGCGATCGCATCGGTACCGATTCTGCCAAAGTCGCCTTTCGCACCTTCTGGAGCCAAGACCATCTGAGCCAAAATCCCTGGTCTGAGGAAATAGACTTCTTCAACGACGACATCAAGCCGTTGATGCAGACCAACTACTTCCGTCGCATTGGCATCGACGGCTTACCCTTGGATTGGTTCTGGCAGATCGACGGTTGGTTCATCCTTGTATTTGGTCTGGAGCTGGCAGCTCGCTCCTTCTACCTCTGCCGTCACTACAAAAATGTCACCTGGCTCGATGCCCTCTTGTGGCGTTGGTACGACCTGTTAATGGTGCTGCCGTTTAGTGCCGTGCGAATGCCCGTCCTCGGCTTGAGCCGCACCATCACCGTTGCCATTCGCCTCGATCAGTCCCAGTTGATCGATTTACAGCCCTTACGGAATCGCATCAATCGCTTCTTTATCAGCCAAGTGGCGATTGAACTCACCGAGGTCGTGATCCTGCGCATTATCGATCAATGTCAAAACCTGATCCGAGCCGGAGATGTCACCCGCTGGTTAGTGGATGCCGGCACCGGCCGCCGCTACATCGACATCAATGGCATCGATGAGCTACAGGTCATGTCCCAACGGTTCATCACCATCCTGGTAGAGCAAGTGTTGCCCCAAATCAAACCAGAAATCGACGCCGTACTGAACCATAGCCTTAACCAGGTGCTAGGCCAAGCCCCAGCCTATGGCGGCCTGCGTCGGCTACCTGGCATTGGCACCCTGCCTGATCAACTGGCCCAGCGCCTCGCTGCAGAGATATCTACCAATGCCTATGACGCCCTCAAGCAGACCCTAGAGGATGATCAGGGAGCGGTACTGATCCGCAGCCTGGTGGCCAAATTGACCGACCGTCTACGCCATGAGGTGCAGCAAGATGACACCCTGGATGAATTCGAGTCCCTGACCGTAGCCCTACTGGAGGAGGTCAAGCTCAACTATGTGCGTCGCCTGGCCGCCGAGGACATAGAACAGCTGATGGAAGAACGGTACCGCCTCTACAACGTCACTCAGGAAGGCCGCGCCTCCTCCAACTAAACCCCGAGGCAGCCTCAGCCCCCTTGCCTACTCACTACCTGAGCGGCCACCAGGAGACCTTGTCCCGAGTCGCCCCATAGATCTGCTTTAGCGCCTCTGGATCCACCACCTGTACCGTATCGGGGTTGGAGTCAGCTGCCTTACCGGCCTTGAGTAAGCCAATCTGGGTCATCCCCTTGAGTACCTGTTCCACGGTGCGATGGTTCAGTTGACAGGCGCGGGCAATAATATCAACTGGCAGGTCAAAACTGTAGGTACCATCTAGGCTAGGTTGGTTGCCTAAGGATCGTTCCTGATAAATCAGGGCCCGCAATAGGGCTGCCACTGCCTGAGGAGGATAGGTGCTGCAGTTTAGCAGATGATATTGAAACTTCTCTCGCATCTCAAATAGCAAATCATACCGCTGCCGAAACACATCACTATCTCGGTAGAGGGCTTGGACAGCGGCGACGGGTAATTTGATCACATCGGTGGTTTTATAGGCTTCCACTAGACTCGGGAAAGCCCTCAACACCGGGCCATGGCTAAAGGCGAGGTTTCGCATGCCGAAACACCCGCCGGGATAGGTCAGGGCGATGATCCGATCGAGAGGAGTGCTGCGCACCACCACCGGCCCGCCCGCCACGATGGCATAGAGATGCTCCAGCCAGGTCTGGGGGCGAAACGCTGTAAATACGGGGCGATTGGAATAAAGTTTCTCTAAAATCAGCGTGTCAGGAGACAGGTAAGACGCCAACCAACTGGGCTCCATGTGCCGAAACAAAACGTTCCCCTGGATCAGGACCACAATCGGGTCAAAGGCATTAGCATGCTTGGCTGGTTTAGCCATGGCGAAGCAGGAATTTGTACCAACCCTGGTTTATTGTCCCATGGAGTCGAGGAGGAAGGGATTAGGAAGGGATTAGGAAGGTTAGGAGTAGATTTGGTCGGTTCTGGGAGCAATGCGCTACTATAAACGATGGACAGCTTTTAGAAGGTGTCCTCCCGTTTCTGATAGGTATTGAGGAAAGTGGGTTGGTACCCACTTTTTTTTATGGGAGTTGGTCTATGACACATCCTCTCATCCCCCAAATTTTGGATTTAGCGGCTCCGGTAGCCGAACGGTTGGGATTAGAGATCGTCGGGGCGGTTTTTCAGACCAATCAGGCTCCGCCTGTGTTGCGGATTGATGTGCGCAATCCCAGCCAGCATGATACCGGATTAGATGACTGCGAGCGAATGAGTCAGGGCATCGAAGCAGTACTCGATGCTACCGATATCATTCCTGATGCCTATGTACTGGAGATTTCTAGTCCTGGCATTTCGTCTCAGCTCACCTCGGATCGGGACTTCATAGTCTTCAAAGGATTCATGGTGGAGGTGCACCTATCCACACCCCACCGGGGTAAACATCAGTGGGTAGGCCAATTAATTCGCCGCGACGACACCACCCTTTATCTCAATCAAAAAGGTAAGTCCATTTCCCTACCCTGGAAAGCTGTTGAATCAGTTCAACTCAGTAATCAGTCCGTTGACTAGGGTGCCCCCTTTCCAAGCCTGTCGGGTCTCCCCCTCACTACCATTTTACCTGGAGGTGTATGCCATGTCTCTCGTTAATTTGCCAAATTTACAGGAACTGATTGACCACATCAGCCGTGAGCGCAATTTGCCTAAGCACGCCGTCGAAAATGCCCTACGAGAAGCCTTACTAAAGGGATATGAACGCTATCGGCGCACTCAGCGCATGGATGGTAATGTCCAATTTGAGGAAGATTATTTCGACAATTTCGATATTGAGCTAGATACCGATGAATATGGCGAGCAAGGATTTCGGGTCTTAGCCAGCAAGGCCATCGTTGAAGAGGTGCAGAGTGCTGATCACGAGATCGCGCTGGTAGAGGTGCAGGAAGTTGCTCCCGAAGCTCAATTGGGGGACACGGTGGTGTTAGATGTTACCCCAGAGCAGCGGGAATTTGGTCGTATGGCAGCGATTCAAACAAAGCAGGTATTAGCCCAAAAGTTACGGGATCAGCAGCGTAAGATGATCCAGGAAGAATTTCAGGATTTAGAGGGCACGATTCTGAATGCTCGGGTGCTACGGTTTGAGCGTCAGTCAGTGATTATGGCCGTCAGCAGCAGCCTCGGGCAGCCTGAGGTCGAGGCTGAGTTGCTGAAGCGCGATCAACTGCCTAATGACAACTATCGGGCTAATGCTACTTTTCGAGTGGCGCTCAAAAAAGTATCGGAAGGATCCCATCGTGGCCCTCAACTGCTGGTGTCTCGGGCCGATGCCAGTTTGGTGGTAGAACTCTTTTCCAACGAAGTACCAGAAATCGAAGATGAAATTGTGCGGATTGTGGCGGTGGCACGGGAGGCCAATCCTCCCTCCCGTTCTGTGGGGCCTCGCACCAAGATCGCAGTGGATACGGTAGAACGGGATGTAGATCCGGTAGGAGCCTGTATCGGCGCCCGCGGTTCTCGGATTCAGGTCGTCGTGAATGAGCTGCGGGGCGAGAAAATTGATGTGATTCGCTGGTCTCCGGATCCCGCCACCTATATCGCCAATGCTCTGAGTCCAGCTCGGGTGGATGAGGTGCGCCTGATGAACCCAGAAGAACGGCAGGCCCATGTGTTGGTGCCCGAAGATCAGCTCAGTTTGGCCATCGGTAAAGAAGGGCAAAATGTACGACTGGCGGCCCGTTTGACGGGCTGGAAGATTGATATTAAGGATGCGGCTAAGTATGACTATGCCGCCGAAGATGAAAAACAGGCTGAAATCCAAGCCCAGCGGGAAGCTCAGCAGCAAGTAGCCCTAGCAGCTACGGCAGCAACTGCCACCGATTTAGAGGCCAATCTAGAGGATGAGAACGGGGCTGCAGAGGAAGCCCTAGCTCCTGTGACAGGTCCATCCTTAGCTGATGCCGCCATGGCAACAGAAGAGAGGGCAACTGCCAGGGAGGCAGGCACACCAGAGGCCTCAACGCCGGCAGAATCAGCTTCAGAGGCGGTGTCGGATAACGCAGCGTCGGCTGAGGATTCCCTGGAAGAGAACACGCTGGCAGAGGACCTTGAAGAGGACACAGTCGACGAAACCCCCGTCGAAAGCGATGAAGCCTATCCAAGGGAAGAAGAGTAACCAAGCCCCGCCCACTAGTATGGAATAGCACCTTTTATTGAGACCATCGTTTGGCTCCTATCCTGGGTGGGGGCTGCCAATGAAACCCAATCTACGCCGCTGTATCAGCTGCCGCAAAGTGGCTCCGAAGTCGGCCCTTTGGCGAATCGTCCGCGTTTTTCCCAGCCGGACAGTACAATTAGATGAAGGTATGGGGCGGTCAGCTTACCTCTGTCCTCAGGTAGATTGCCTCCGGACAGCTCAAAAGAAGAACCGTCTCGGACGTGCCCTGAAAGCGTCAGTGCCACCGAGTATCTACGAAGAGCTCTGGCAGCGGTTGGAGTCTTCCTCGGTTAAGGGGTCTGAGCGCTCCTCACCAGATTGAAGGGCTGTCCTGTCAGTAAATGGGCAACTGCCCCAAGATTGTCTACTGTTACCCGCTGTTCAGCTGTAGCGGTGACTGATTAAACTCAATAGAAGAGGAGTATAGTCTTTATGCTCTGCTTTGATGACCGACGATAAGCCTATCAACGGTCAGCTTGGGTGAGGTAACGAGTCGTTTGCATAGGAAGGTTGATGTAGTTTCGTTAGAAAAATAGGACGGGCATATGGCATAGCTAGGATTGTCAGAGGGAGATTTGGATGAACAACGGCAAGATCAGAATTTACGAATTATCACGGGAACTAGATTTAGAGAATAAGGATATTTTAGCGATCTGCGATCGCTTGAATATTGCCGTAAAAAGTCATAGCAGTACCATCACTGGTGAAGACGCTGCCCAGATTCGGTCGGCTGCTAAATCGGCAAGGGCTGGTAAGGCTAAGCCTCGACAACCTGAGAAGGCTCATAATGGCGCGCGTCCGCCAGTAAGGAAGCAACAAATCTTAGAAATTCGTCGCCATCGAACAGCGCCCAAACCGCCGAATGCTCCTGAACCTCCCCAATCGCCAGAGGAGCCTGCTGCTATCGACAATGATGAAGTCAGCCAGGGAGAGGTTGATGCTCTGATGACCCCTCCCAGCCGTCCGGAGGCTCCGACGCGTCCCTCTAGCACCCAGCTAAAACCACCGGTGAGTCGTCCACAATCCCCGGGCCAGGCTGAGGCTGAATCACCTCAGCCACCGAAGCCGAAGACAGCTAGTCCGCCGGAGCCAGAGGAGCAACCCGCGGAGCCGTCGGAAGATAAGGCTACTGCTCCGGCGGCAAAGGCACCTAGTAAGCCCAAGCCAGAACTGATTGGACCGCCTCCCAAGCCGACTCGTCCTAAGCCCAAGGTCACCAACCGCCGGGCTCAAGCTGATACCTCCGAGCCGGCGGCGAAGTCGGCTCGACAACCCACTATCCCGATTCGGGAAGTAGATGATGATGACGACGATGGGCCGAAGCTTAAGCCGAAGCCGAAGCTACGTCGTCCCAAACCATCAGAGCCGCAACAAGACGAGCAGCCCGTCACCCCTGAGCAAGATGACACCGAAGACTCGAGGGATGCTAGGGATGACTCTGCCCGTGAACCATTGCTGAAACGGCCATCTCCATCGCGATCGCAACGCCGCAAGACTCGAGAAGAGCCTGTTGATGAAGAGCAGGAAATGCGGCCCAAGGCTGACAAGAAGAGCAAGCGGCGTCAGGCCATCATTGAAGATGATGACGAACTCGAAGAAGTGATTGAGGGTGGATCCGGCGGTCAGTCCGATGCTTCCTCTAATCTAAGTGTGTCCCTAGCTCGGCCCCCTAAGCAGAAGAAGGCATCTGCTTCGAAACCCTCTGCACCTGCGACTCGCTCCTATAAACCCCCTAGTCGCGATCGCAGCGGCAGTAGTCGTCAACAACGGCGGGAACGGCAAGAGCAGGCCACCCAGCAAGAGCGGCCAGAAATTCTGACTCTAACCAGCGAACTGACTGTACACGAACTGGCGGCCAAGATCGTTGTACCTGAAACCGATATCATCAAGTCCCTCTTCTTCAAGGGGATCGCCGCTAACATTAATCAGACTCTAGACGTCCCCACGGCCAAGATGGTGGCTGAAGAGTTCGACATTCTGGTGGAGACTGCTGAAGCCGAATCTGAAGCCAAGAAGATCACTGAGATGTTAGATGACAGTGATCTGGAAAGCCTGGTGCGGCGACCGCCAGTCGTCACTATCATGGGCCACGTTGATCACGGTAAGACGACCCTGTTGGACTCCATTCGCAAAACCAAGGTAGCCCAGGGAGAAGCCGGTGGTATCACTCAGCATATTGGGGCCTACCATGTCGATGTGGACCATGAGGACGACTCTCAACAGATTGTCTTCCTCGACACTCCTGGTCACGAAGCATTTACCGCTATGAGGGCTCGGGGTGCCCGCGTGACCGACATTGCCATCCTGGTGGTTGCGGCTGACGATGGGGTGCGCCCCCAAACCATTGAAGCTATTAGCCATGCTAAGGCAGCTGGGGTGCCGATCGTGGTTGCTATCAACAAGATTGACAAAGAGACAGCCCAGCCTGATCGAGTCAAGCAAGAACTCATGGAACATGGCCTAGTGCCAGAAGAATGGGGCGGCGATGCCATCATGGTGCCCGTCAGTGCGATTGCCGGTGAGAACCTCGATAATCTATTGGAAATGCTGCTCCTGGTGGCTGAGATCGAAGATCTACAGGCCAATCCAGATCGCCTGGCTAAGGGGACAGTGATTGAGGCCAACCTCGATAAGGCCCGAGGACCGGTGGCGACCCTACTGGTGCAAAACGGCACCCTGAAGGTCGGTGATGCTGTTGTCGCGGGCTCTGTCTTTGGTAAGGTGCGAGCCATGATTGATGATCGGGGTCAGCGAGTCACCTCGGCCTCACCATCCTTTGCCGTAGAGGTGCTGGGCTTGAATGATGTCCCGGCGGCTGGCGATGAGTTTGCCGTCTACGGTGATGAGAAAGAGGCTAGAGCCGTGGCTGATTCTCGAGCGACGGAGCAGCGCCAATCCCGTCTGCAGCAGGCCATGGCCTCTCGTCGGGTAACTCTGAGTTCCTTGTCAGCCCAAGCCCAGGAAGGAGATCTGAAGGAGCTAAACCTGCTGCTCAAGGCCGATGTGCAAGGTTCCTTGGAAGCCATCTTGGCAGCGTTGCAACAGCTACCTCAGAACGAAGTGCAGGTGCGCGTGTTGCTGGCAGCTCCCGGTGAAATTTCCGAAACGGACGTGGATTTGGCTGCGGCCAGTGGGGCTGTGATTATTGGCTTCAATACCACTCTGGCACCAGGGGCCCGTCAAGCCGCAGATCGCCTAGGCGTGGATGTGCGCGACTATGACATCATTTACAAGCTCCTAGAAGATATTCAGGGAGCCATGGAAGGCCTACTGGAACCCGAGCTGGTCGAGGAGTCCCTGGGTCAGGTAGAAGTGCGCGCTGTGTTCCCGGTGCGCAAGGGCTCAGTGGCCGGCTCCTATGTACAGTCCGGCAAGGTTACCCGTAATTGCCATCTGCGGGTATTGCGCCAGGGCGAGGTGGTGTATACTGGTAAACTCGATTCCTTGAAGCGCATGAAGGATGATGTCAAAGAGGTGGCGGCTGGCTTCGAGTGCGGTATTGGTATTGATGGCTTTAATGACTGGAAAGAAGGCGACATTATTGAAGCCTTCCGTCTGGTGACGAAGCGCCGCACATTAGCAATGGCTCGGTAATGCAGTCTTTTCGGCTTGATCCCTACCTCTGGATTCACCTAGCAGGACTGGCAGCTGTACCGCTTTGGTTCGATGTTTGTTTACTGGGGCTGGCTGCCGGTGACCCTGTTCTGCCAGTTTGGCTAGAACTAGGAGTGCTGGCGGTTGTAGGAGTGTTGCCTGTGTTGTGGATGCAGTGGCAGCGGCCTTTCTGCATCTTTAGCCTGGTGGCGTTGGCACTGAAGCCAGACCAGATGAGCCCTAACCAACGACGCCTATTACATCTGTTTCAGGATCCCATCGGCCGTGGGGTGTCTCTGCTGGTTCCCTTGCCGTTGCTCTGGGGACTGTGGCAGCTCTATCGCTTGGCTCCCTTAGCTGCGAACAGTACTCCCTTCTCCAATCGAGGGGTAGGGGTGCTGGTGGCTGCGATCGCATTTTTGCTGGTCAATTTGTTTACTCAGGTACCTGTGCGGGTGCTGCGGGTACTATTGGCTCCAGCCACTGCCTTAGACGGGGTAGATCCCTATGCTCCAGAGGCCATTCCCCAAGATTTCACCTTGATTGGGCTGCGGGTAAACCAGATTCTACCGCCACTGGAAATACCATCGGCTGAAGCCCCGCCTGAGTCGCCGTCCCAGCCAGCAGTAACCGACCAAGAGGAAATAGCCCCTGCCCCTTTGGCCAAGGAAGATAAGGAAGATGGGGATGAGACGGATGACACCATTGTCTCGCAGACAGAACCAGCCCCAGAGGAAGAGCCGGCGGCTGCCGAGATGGCTGCTGATGTCTCTACCGACGCAGGATTGGCAGCTTGGCCCGTCGATGACTCGGTCGAAGCCCTGGATTATGAAGGCCAGGCCCCACAACCTGCCGAGTCTGAATCTGTTGACTCCCCAGAGGGAGACGGGCAGGATGGGCCAGAATCTTCCTCAGAGGAGAGCTCGGCCATAGAATCCCATGTCTCCTCAGATGCCCCTCAGCCAGACGACAGCAATGGCTATCATCTTCAAGAGACAGATGTGCAGCCCCCAAAGGGGCATTCAGAGCACGAGCACGAGTCATCCTCGCAGTCGCCAGATGAGCCTGGTGATGCTGAATCAAGGTCAGAGTAAGGGCTGATTTGCCAACCACAGCGCCGACTTGACACAGCCATCAGGTGCTCAAGTGACGGTGGAGTGCGATTTTGGATAATGTTTCACGTCACATTTATGGCTGCTTAACAGACTAGACGGCATTTCTGTGGCATCTAACACAATGTAGCCTGGGTGACTGCGCTATCCTAAGATTGAGCTCGTATGAGGCTGGCTCCAATATAATCTAGGTTTTGGCAGCGAGGCATTTATGACTAGGCTTTCTTCTCACCAGGCTGATCAGTTCGCCGATGATGCCACTATTTGGCAGAGTTTAAAGTGTGCGATCGCAAATAGTTCTGGATTTCAGCGCTGGCAGGGAGAGCAGAGTGAGACGGATCTGGCAAAAACGCCCCTAGAGCAATTGGTTCGTCGTTACCTACGAGAAACCCTCGAGACTCTCGCTTATTAAGGACGACCCCAGGCTAAGCCACCTGGGCTAGTTAACTCAGTGACGCATTCTGCAGTCATTGATAGCACCCTTGCCTGAGATGGAGATCCCCAGGTCTCCATGGTTATTTTTTTATTGGCCGTTACACAATTGGAAACCCCGTCCCACGGTGAATAGGCTAACCCCATACTGGTGATGATCGCCTAGGAAAGTCATCATGGTTTATCGGTTACCGTATTGGGCCCGGGGTGGAGTATTATTAGCGGCGCTCTGGTTAGTGGGTTGTGGTGCGATATCGACACCGGAGTCGACAAGTAATGAGGCCGTATCTGAGGCCATGACCGCCGAGAATTCTGCGGCACCGGCGCGTCAGGATCAGACCGCCGAGGTGGCAGCAGATACCTCTGCCTTACCCGAACGGCAGCCTCAGTTGGTGAAACAAGCTAACATGTCGCTGCGGTTAGCCGATGTAGAGGCAGGTATCGACGCCATATACGATCTGGCCGTTCAGCAGCAAGGGGATATCCTGAATCTTCGAGATCAGCAGCCAGACACCGGCCAACCTCGTCAAGTTTCACTGCGGCTACGGATCCCTCAGAGTGCCTTAGAAGCGACCCTAGACGCCCTGCGACAGCTGGGTGAAGTCCAGCAGCAACAGGTCACAGTTACCGATGTGTCAAACCAGTTGGTGGATCTGCAGGCCCGGCTGCGGAATTTACGCAAGTCAGAGGAAACTCTATTGACGCTCATGGAGCGCTCTGGATCGGTGGCAGATGTGCTGCAGGTGGCTCAAGAACTGAGCAATGTCCGGGAAACCATCGAACGCCTCGAGGCGCAACGACAGCAATTGAACACCCAGGTAACCTACGCCACGGTGCAGGTGCAGCTGGAAGCAACGGTCACTCCGGTCCCCACCAACCCTCCCTTGGCGGAGACCCTAACCAATACTTGGCAGCAGGCTACCCATTCCGTCAGCGACCTCAGTACTGGCGTGTTGCGCCTCAGTCTCTGGCTGATTGCCTACAGTCCCTATTGGGCGCTGGTGTTGGCAGCAGCTTGGGGGTATCGCCGTTGGCAACGGCAGGCCCAGTCCTCTTCTTGAGTGGTAACAAGGAGATCCCGTGCCTCTGGGCGGGTAATGCTGTGCGAGTACTACTGCTAGAAAGTCCTGGGAACTGCTAGTTAATCGGCCCTTTTCTCTAGAATTCTGCTGTTTTGTCGTGGGATCGCGTCCGTAAAGATTCACAGTATTTTCATTCGCAGCAGCGAGAACTTAAACGAGGATTTTAGAGGCAAGCAGTACGATTGAAGTTACACGGATTCCATTTGAAGTTGTCCCACCTCCCCTGAGCCCTGGAGACAGATTTCGTTAAGGACATTCGTTAAGGACAAAGGAAAGTGCTGGGGAGCAATGGGGGCGATTAAGCTGAGCATTACATTGCAGCAATCTGAGATTCGTGCCCAGTCTATTTTCTAATTTTTTTATTGATTTTTGTCAATGGGATATCGCTTGTAATGATCGCAGTATCTTTCACCCGAGTAGCAATGTTTAGACACTTATAGACACTTACCTTAAAGCAGCATGCTATTTTGCTTGAGCGTTACGTCAAAAAATTTACCGTAGAGACCAGCGCTCAGGCTGCATTAAATAATGAACTGAGCCTGGTGTATACTACCCACCTAGATTTAATAAAATGACCTCATCAATTACCCAAAACAGCCTTTATCAACCCCTGCATCCTTTCTTGGTCGCTGACCATACTGTTGACTTTTCTGGCCCTATTCCTGTAGACACTGCCCTAACGCCGAGTCCAGCGATTACGGCCAATAGTAACTATTTCGATCATCCCGACTGGGCCTTGAACTATTTCAATGCCTGTCATCGTACCGATGGTTTTAAGGAGCGCTGGCAAGCAGCGACTGGCACCTGGGATGACAAGATTGTGGTAGATGTGGGCTGTGGCCCTGGCAATGTGTTTGCCACGGTGGGCGGACAGCCGCGGTTGTTGATTGGGGTGGATGTGGCCTTGGGATCGCTGGCCCTAGCGCAGGAGATCGGCTATGTGCCATTACTGGCTGATGCCCATCAAATGCCCTTGCGATCGCACATGGCCGATCTAGTCCTCCTCAATGCCACCCTGCACCACTGCGAAAATATGGAGCGGGTCCTAATCGAGGCAGCTCGCCTAGTCAAGCCCGGCGGCAAGCTAGTCATCGATCACGATCCCCAACTGCAGGCCTGGAACTATCGAGGCCTGGGCATGGCTATGTATCGGATTCGTCACCATCTCTATGCCCGCTGCCTAAAGGACTTGGACATGGATCCCCATGAGCGGACCTATGCCCTGGCCACCGAAATTCATCACCATCCCGGCCATGGCGTCACTGCCGAATTCTTCCGAGGCAGCCTGGGCCAGCTTGGATTTCAGGTCAATCTCTATCCCCATAACCAAACCCTAGGAGCCGAGACCTTACAGGGCCAACGCGGTTCCTTTCCCCATTGGCGCTACCCCCTAGGGCAAATACTCTCAGGCATTAACCCCTGGTCTGACGAAGCGGCCCTCTCGCTATTGTGTGTGGCGGTTCGAGCCGTTGCCGATTACTCATAGGAACTCTCTGGAGACTAGAGGTTCCATGCCCAGTTACACTAAGGCTATGGCTTCTAGGCTGGAGACAAATCCCTATGGCCCCCCTTCCGCAGAAACGGCCCCGCCAACTCTCCCTGGGACCGTTAGAGCAGGAAATCATGGCGATCATATGGCAAGCGAACTTGACCACGGCCACGGCTATCCATGGGTATATCCTTAGGGATCCTGATCGGGAATTGGCCTATGCATCGGTAATGACGGTGCTGCAGCGTCTCGGTAAAAAGGGATGGGTTACCTGCGATCGCAGCCAGCGTCCCTATCGCTGGTACCCAGTCGTGTCATCCCAGGAGGCCGCCGTCTGGAAGGCTCACCAACAGCTAGCGGACTTTCTGGCGGTTGGTAATCCCGATGTGGTGGCGGCTTTCGCCGATAGTCTCGATACTGCTAGCGTAGAGCAACTAGACGCCATTGCCCGGCGTATCCAAGCCATTCGACAGCAACGACAAGCGCCTTGATGCATCTGAGCTTATTGCTACTGATAGGGCTGCTGGCTGTGGTCATGCGTCTGCTTTGGCCGCGACCTCAGGGATCTTGGCCACAGCGCTGGTGGTCTACCCTGCAAGGATTCTCCCTACCGCCGCTGTTGCTCTTGACGATGGCTTTGGCGGTCTTGGGCATGGGGGGACATGGCCACATGCTAGGTCTGCCGGTCAGCCATGGGGGCTGTGGTTTGGCCTTGCTATGGTGGGGCATTGCCCTAGGGCACTTAGTCTGGGCTGGCGGACAAATGGTGCGATCGCATCAGCAGACAAAGCACTTACCAGTCCTAGCCCTAGCCGACGATCATCCTGTCAGCATTTTGCCCGTAGCCATTCCCTATGCCGCTCAAACAGGCATCTGGCAACCAAAAACCCTCCTCAGTCAAGGGCTCTTGCAGGAGCTCAACCAGGAAGAACTCTCAGCTGTCCTAGCCCACGAAGCGGCCCACTGCCACTACCAAGATCCCTTCTGGTTTTTCTGGCTAGGCTGGCTCAGGCGCTGGAGTGGCTGGTTACCTCGTAGTGAAGACTTTTGGCAAGACCTGCTACTACTGCGAGAGCTGCGGGCCGATCAGTGGGCTAGCCAACGGGTCGATCCTCTACTGCTGGCTAGCGTGCTCGTCAAATTAGCGGCTATGCAGCAATCGCTGGCCATTCCCGGCGCCATCTCACTACACGAGGCTTCTCTTAACCGTTTAGAAGAGCGAGTCGATGCCCTGCTAAACGCTGCTGCTACTGACTCAGTCGATAGTCCTGCCTCAGTTTTTCCTTATCCTGGGTGGTCTATGGCCCTACTTCCCTTGCTGACAATTTTGTTGCACCAGTGAGGGAATTGGCCAGGGATGAGGCAACTGGCGCAATCTAAAGCCGCGTCAGCCAGCCAAACACCCCTTGACCAGTCAGGGCTTCAAACAGGAGGGCCGAGACAAACCCGATCATGGCCAAGCGGCCATTCAGCTGCTCGGCATATCGGTTGAAGCCAAATCGCTGATGGTCATCGCCATAAACTTTAGGCTCAACCGCAAAATTATTCAGGCGGATTGCCCGCTTCAGGGGTGTATCCGTTGGGCGTCATGGCAGCATATCCATCTATCTGCCCACATCGTAACGCAATGTAAATACTTGTTGCATTTTCTTGGTAGAAGGGTGAGAACTGCCTAGGTGATTGCCTGAAAACGCTCTATTAGCTGCCGCAGCCGTACCTTGATGGCAATGTACGTAGACACCTGATAGTGTTCAGCCAACAACCACACCACCAGAGTCATATGGGTCAGCAGGGTGATGATGGCCCAGGCAATCGGCCAAGCCAACGCCTCATCTAAGGGTGGAAACATGTAAGCTGACACACTGATCAGGCCGACCGGAGCAATGATGAGCAAAATGCCCACGATCCAGACCATCAGCGTCATATCCAGATCTCCCTGGCGCAGGGATTTCCAAGTACGACCGTTCCACCGCCAACCAGTGGGCTGGGTACCATCGACCATGTGAATGGTCTGCTCACTCAGATTGGCCGCAAACATATGTCGGCAAAAGTCGCAAGAAAACGACTCCATCAGGACCAAGGCGTGAATATGGCCATGGCGGCAGACTGGACAGAGATACTGATTTGTCAGGCTGAGTCGCACTGGTTCGGCTCCTGACCGTTCCCTTCCCTGATGCGTCTGCTGCGGGTTAGATGATAACCAAGCCATAGGAGGAGATGAAGGCAATCATGGGGACATTGCTTAATTGCTTAGAGCATACCGGCAACCACCATGCTACCGATGGTGCGGGTATAGTGTTGGCCATTGTAAGCGAGAATGACAACCGGCTCCTCGGACATCTCAATACGATGGACTCGCACCCGCCCACCCGCTAAGCTATCTCCGACACTGACGTAACGGCTGGTTTTGGCATTGGGTTCTTTCACAATTAAATGGATGCGATCGCCAACTTGCACGACCCCACTGAGTTCAAGGGCATCTACTGGGTTTCGGGCAGGAGAAGACGCTGCCGCTACTGCAGGTGTCTCGGGGGCAACTTCACGGCTAGGTAAGGGGGGCAAGGAAGCCGGGGGGGCAGTGACGGATACAGTTGGCAGGCTCTGGGGAGGCGTCGCCACAGCCACTGGAGTCGTGGTCGCAGCGGTGGCAACTGGCGTCGCCGTCGCCGCGTCTGGACCAGTTAGGGAGGGTCGGGTCAGGGGAGCAAAGGGATCGGTCCGTCCAGCAGTCACCTGGGCTAATCGGGCTGCCTTATCGGATGGCTGTAACAGCCCGGGATCGGCCAATGTCAGTAGTGATGTTGTCGAGGCCAAGGGAGAGGTGAACAAGGGCGGTGCTGGGCTAGTCTCTGTGACGACCTTTGGAGTCGAAACGTCTGCCTGTTCCGGCGAGGCAGTCATCAAGCGCACTAAGCTACCAACGGCCAACGCTAGGCCAACGCTGCCAGCCAAGACCCAGATGACCTGACGATTTGAGAGTGTTTGCGGTGCAGCGGATGGTGTCATTGCCAATTCCCCAGGACTAACCCACGAGCTTCCCTGTAGGATAGCGAATTATTCCTAAAATAACGTTAGATTAACGCCATTTCCTCAGCTTAATAATTTTGCTCAATACGCTCCCTGGTTGGCTGGGTCCCCCTGGCACGCCAAGGCAGCAGATTGTGATGAAATACATCCCGGCGGAGCCATAATCGTATCCCTGCAGTCGAATGGAACGACGATGGTGGTTTTCGGGGTCGTAGTTCATCAGAGATATGCGATCGCTTCTCCAGTTAGAATTCCCTGAATATCGGGTGGAGGCGTATGTCTGCAGATCACACATGGGATAGGGGCGCCCAGGCTATTGGTCGGGGCGCACGGGCTATCGGTCGGGGCGCCCAGGCTATCGGTCGGGCGCCCAGGCTATTGGTCGGGGCGCACGGCCGTGCGCCCCGACGGGCGGTGGGGTACCACGTGTAGGGTTTGCAGAATCGGTGTTAATCCTTCAATGTCGCGGCATCGGCCATAGCTTTTTGAATAGCGTTTGCTGGCCATTGAGAAACGCCAGCAACTCCTCCGATTCCACTGAGCCATCGGGAAACAGGGTGACCAGCTCGCAATATTGCCGGGTGACTAAGGGCATGGGCTTTCTAGGATTCTCAGGATCTTTCACCAGCCGCACTTTGGGATACATGCGATGCCACAGCCGCCCAATAGTTCCCATTTGCCCCGTCATTGATGACCGATAAATTGATCCCTCGGGAATGCCAACCGACGGAATCGCCTCTCGATAGGGGCCATGCAGCCATCGCACCGCTTCACAATCGTCCAGGCCATCGGTTTCACGTCCCCACACCTGCACCCTGTCTGGATGCCAGGCTTCTCGCCAGTTGGCATGGGTATCGGGTTGGGGCGTCACGGTTTGCAACTGCATCCACTCTCGGGCCGCCTAGCGCACTTCGGCAATGAAATCCCCTACTTTTTCCAGCTTGCGCACCCGTACATCCCGTACCTGGGACCGTTTACCCAACCATTCCCAGTGGCAGCCGATCAGCGGTTTGTAGCCCTGGTCATAGTAGTCGGGATAGACCAGACGATGGTCGGCCCGGCGCCAGGATTTGCCAAAGCCACCGAAGACCATGGCAAAGCGGGTCAAGGCTTCAATCAGTTTCGTTAGGGCTTGCCGCTGGGGCTGAGGTAGGTCTCGGGTGAGCCGCCAGAGCAGTTCTCCCTCCACCGTGTAAGTAGGCTGACTATAAGAACCTTGCCCAAAATCATCTAGCTCCAACTGGGTGTCGAGAAAGGCCATACTCAGCAAGCCCACAGTGGCTCCACCCCTAATGCCGCCAAACAGCTCCTGGACCAAACCTTCAGCTTGATCTGCACTGGTTAAGCCGCCAAAGATACGCAGGGCATGGCCCCGGATGGCGGCGCGAAATACGTTGGGGCGAAACTCTCCGGTGCCATCCACTAGCTTGGCAGCCTGACCCTGCCCCTTGAGGCGCGTGCGGTAGAGAATATCGCTGCTGCGTTGTTGGGGTTGACCATAACCGGCACTGACGCGACAGCCCAGCCCCAGGGACAGCGCCGTTTCCCAAATATGCCAGATTTGCTCCCATTCAAGGTCATCCAGGGGAGTAGTGCTGGAGATGCCGACTGCCAGCTTAGGTTTATAGAGGGAGATCTGTATGAATGCCCCGCCTTCCTTCTCTCCAGATTTCACCTGCCACTGCTGCTGGGGATGGACAATATCCACCAGGTTCTGAGTCCAGCGGGTATCGGTGGGGTAACCGCCATGAAATCGTAAAATGCCGGGGCGAAAGTCATCATTTTCTAGTTTTTCGCCGCAGTAGCGATCGCATGTCCCTTCCGGTAATTCCCCCGTCCGTTCCAGCTGCCGAGCCGCCTGGCGGAACACGCCCTTCATGCTGCTGCCGGGGTAAAAGGGCCAACCCCTGGCCCCAATCACCGGACGAATCACCCCATCGTCTTGGCCGCTATTGGTAATGAAGCGCCAGCTCAAGGCATAGGTGCGGGTTTGCACGTCTTTGCCAAAATCAGGCGCCTCTGGATAGGCCTTGTCGACCCATTCATCGGCCCAGCGCTCGGCATCTTGCTCGGGGGCCTTAGGGATCAGCCGCTGCACCTGGCAGCGACCCTCCACTTGGGCCCGAAACATCAGGGGGACTTGGTTGGCGATCGTAGAGGAGTGAGCCATGGGGATACCTGAATCGAGATTTAAACCATCAACCAACCAAACAGTTGGTCTGCGGTGAGGGAGAGGTTAATATCCGTCAGCACTGGCAGGGGAACATCCCCCCTGAGCAACTGCACCCGCTGATCGGACCAAACCACCAGGACCGTTTCTTCCTCCGGGTCAAGCAACCAGCCCAGTTCGGTGCCCTGTTGGGCACAGTGCAGCAGGTTGCCTAACACGCGAGTCTGGCTCTGCTCAGGTGAGAGAATTTCGATCGACCAGTCTGGGTGAATGGTGAAGCGATTGGCGATGCGCCCTGAGGGTTGACGAGGAATGCGGCTCCAGCGAAATACCGCCACATCAGGCACGATGGATCGACCAGCAACCGTACAGCGCAATTCAGGAAAGGCCATGGCGACTTTGGCCGCCTTGGCTTGCTGATTAATCGTTTCACACAGGGTTCCCTGTAGCAGGCTGTGTTCCCCTTGTGGCATGGGTTTCTGGATGACTTTGCCATCGATAAATTCAGAGGCGGGCTTGGTTTCAGGGAGTTTTAGGAATGCTTCCAGGGTGAGCGATGAGGTTGAAATGGTCATGGTCTCTACTCTTCTTCAGCGAGCTCTCCAGCTGCCAGTAGTGTCTCCACCGTCAGGTCCAGCTCTGGAAACGTTGGGGATACCAGTGGCTGATGGCCGACAAACACCGTCTCCTCATACATGCCTTCGTCAAGCTGCAGCACCGTCACCGTTGACTGCAAGGGGTCAACGATCCAATATTCTGGTACGCCCAGGGCGGCATATTCCGTGCGCTTGTAACGGTAATCGCGGCTGACGGACTCTGGACTCACCACCTCCACCGTCAGTAAGGGAGCAGTTTGGCAAATGGCGGATTCATCAAGAAAATTGCTGACCTGCTCTGGAGTTAGTACATAAACGTCAGTCAAACGTGATTTCCGGACGCCGGTACGAATCCCCGCTTCTCGAAAACACAGCCATCTAAAGCCTAAACGACGAATTTCAGTATCGAGGCACTGCTCAATGAATTTAGCTATCAGCATATGCCGAAACGTTGGTGGCGTCATTGCGACCAGTGCTCCATCCACCAGTTCGTAGCGAGCGGCAGTGCCGTCGTCGTAGGCGACATAGTCTTCAAAGCTGATCTGGGTTGTGGCGGTTGACGGTGTCATCACACCCCCTCCAGTACTAAGGTGCTGTGGGTGTTTTTATTCTGGCATCTCCCTAATAGCTGGCAGTGACACCAAGGTGGTAGGGTGGGCATTGTCTCATCTAGAGTTTGGGCTGATGGTGATTGAGCCAAGCAATGCCCGCCGTTTCGCATAGTTGGTGGGCAAGCCAGGATTGTCGTATTTTGCTGAGGTGACCTGTGATGGGATTGCCCACCCTACTTTCCTTGGTTACACTCTGAAACCGCCCCAATTCTGTCCAGGGATATGACAACCATGCTGACATCTGGTGACGTAACGATCCGGCAGGAGTTATCTCAAGTGGGCATAGGTGGCGTGACCCAGTTTCCCTTGCCAGAGATCACTCTACCCAATGCCTGGCCCTTCTTTGGGAAAACAGACCTCCCCCTCAGAGTCGATGAGACGCTATGAAAACAATCCGCAGCCTGCGCCTTAGTCAGCGATTACCCATTTTATTGGGGGTGGCATTGACTGCCTGCGCCCAGATCACCGTCACTGGACTGACCCAGGGAGAACAGGCGAATCAAACCATCACCGTCAACGCCCTGGAGATCAAACGTGGGCGAATTGATACCCTGGCTCGGGTCCAGACCTTTCAAGGTCAACCCGCTGTTGATTCGATTAACGAGCTCGCTATTCAGCTCAGCATTACCGAAGCCAATAATCCGCCGGATTTCAGCGAAACCTACTACTACCTCGCCATCAGTAGCCCCAAAGAAGCCATTCTGGGAGGAACGACCGGTGACCCCAACTATGTCCCTAACCAAATTGGCAAATTAACGTTTCTGACACTTAATCAAGGTGATAACCGAGTCGAAGCCGCCCCCCAAATCGGAGATGCCCATGCAGGCGCATCCTGGTTGGCGAGAGTTGAAGCCGATGATCGGACGATTCCCTGGTCCATTACAGAGGGCGATAATTGCTTTCTGCTCGAAGCGGAGGAGGAAGATTGCTTTGATATGGAAACCCTGTCTCGTCTGCTATTCGAAACCCTGGCAGACTCCATAGAACAGGGTATGCGCAACGATATCCCAGCCATCCAAAGCATTCGCCATCGCCTCCATTTCGTACCGCGAGTGAGTCATCCAGCGATCGGGTTGAATAACCGACCGGCTAAGGGCTTCGGGTTTATCTACTTTGCTCAAATTAATGTGCCCGGTGCCAATTTCCAGGTGTATATACCCATTAATTTCTTGTTTATTGCCAATGTCAATCAGTACATCCTTGTGGTGGACCCGCTCGAATTGGACACCCAGGATCAAAAGACCATTGCCCAAATTTATGTCAAAGAGAATATCGCTGGGGGCATTGATCTCAACCTTACCGAGCAGATTATCCGCGACCAACTCATCGACCAACTCCAAGCTGCTCCCTTACCGGTTCTGATTCCAGGTATTGATTTTTCCGAGGCCCTGTTAACGGCCATGAATGGTGCTGCTGGTAATCCCTCGCAACTCTCCGATGATTTTGATATTTTATTGAGCCCATCTGGGGAAAATCGGGATCTGGCAACCACCATTCTATGGGAACAACTGGTTCCCGGTAATATCCTGCCCCGCAATCAAGTCGACCTTTTCTTCCTGGAGTAACCCGAGCTTGGGTTAAGTCATTCAATCAGAATTCGCTCCCATGGAGCGGCCGTCGTGTGGGTTGAGGCACGAAACCCACGACCCTTTGAATCAGCTTTTGCACCGTGACTGAGTTCAGCTCAAGTTCAGCAGGGAAACTGGCGGCGGGGACGGGGCTGCAGCCAGTGCTTTCAGTCCGGGTACCTAGGCCGCGAAGCCATCGTGGAGCTGCTGGAAGTCGATGATCGCATTCGCGAGATCATGTACGACGGCACCATTACCCAATTGCAACATCACCTCAGCAAAGTCGGCTTCCTATCCTTTCGCGGTGCGGCCATTGAGAAGTTATTGACCGGCGCCACCACCTCTGAAGAAGTGCTCAGGGTGCTTCCCCGCAGTTCTTTGACCCGAAAAACAGCGGCCGATACGGAGGTTTTACAGCTGGTGCCCTCTGGGTCAGACGCATTTGCCGTGGCGTCTGAAAAGCTTACCTATAGCTAAGTTCCTCAGAAAAATGGGCAAGCCAGAATTGTCGCATTTTCCTGAGATAACTGACATTTCGCAGGTTGACAGTATTTTTTTGATGTGCCCGGCTTCTCTACGCTGAGTTTAGGAGAACATCTATAGAGTCATTTCGAAGAATTGGTATTATTTCCTAATTAGAGAGGTTGACAATGTTTTTAGGGCTTCATCTATTCTTTGAAGACCACATTCAGAACTACTTTCACTCCACTCTAGTAATGCATAAGTACGGATACCCTGTGCTGCAGAACTTTTGGGTATGACATTAGAGGGTGGCTTTACTATGAATAGGAGTTGTTCAAACTGAACTTGTGGAAGATTTTGGATTAAATCAAAAAGTTCGTTCCGCTGCTTTATTTCATCGTAAGTTTTAACTTGATCTTCTTCTAAATATTCATCTGATTCTAATTCATTTTGAAAGAAATCCCTAAGGCAGGTCAATAGTGAGCAAACATCATCACTAATTAAAAATCCCCATCTCTCAATGATTTCATTAATAATGTTGATCAATTCGGAAAAATCTTTCTCTTCATATAAACCTATGCAAGTCAATAGCTGACTACCGCAATTATAGATTTCTTCCTCATCGCTGTCTTCACCAGCCTGTAAGATGGAACTAGCAATATCTGCAGCATATTTAGTTGATTCAATGAAATTCATCCAGAATTCATTAATTGCATCTAAAAGGCGATCAGTTCCAGTAGCACAAATTTCATGGTAATAAAATTCTATTTGGTGCTTTTTTAGATAATTCTCATAGCGAGAATATTTTGAATCGTTTTTTTCTAAACAATCTAGATCCTGTCTTATTTCGGACAGCAAATCTTGATAGTGTCTGCTCAGCCTTCGGGAGCATCTCAAAGTTGCAAAAACATCAACAATCGTAGGCTCTATTCAGATAGGCACATCGCACCTGCAAGGCTTGCTGAACATTGTCGGGCACCCATTGAGCGCCTGGGAGTTTCATGCGATGGTCAATCTGCTTGATGGCTGACTCAACTGCACCTGAGCCAATCGAACAGATTTGTTCAGCTTGAAAATAGCCGTAATTCACAATTCGGTGACGATGTCGCTCCAAGTAATCACAGAATCGCCGGGCTTGCTCCAGAGCGCAGTCGGTAAATAACGCCTGGGTTTCATCAACCCGCCCTTCCCATAACAGAGCTTTGGCTTGTTTCAGCCGTTTTAATGAGCCCCCAACTCCATAGAGGTTTTCGACCAAGTGGTACCAATCGAGAATTTCTAAACGGGTTTCCACGGTGGCGATGGGACGAAACACCGCCCAGACGCCCCGATGCCCATCGCCAAGGCAGATGATGGGGTTCGCTAACGGTTGGCTATTTAGCCAGTCTTGCAGCCAGTCATTTGCCTGAAACGCCGCCCCATAGTACAGATTCTCGACCCGAGCACTCTTGTATTCTTTCCAGTAACTGGGTTCGCCTTTTTCCGGATGCCGCAGGCGCACTTTACCGCCATCGACACTGATCTCGGTGACCGTCTGCTTCGCCTCCGGTGGGGTCTCACGTTGGCGTTGCACGAGGCGTTGCAGCGTTGAATGACTCAACGACATCCCCGTTAAAACGGACACGTCGGTTTCGCCTTTCCCATAGCTTTGGCAGGCCGCAACCCGCAACGCACATTTCTCAAAGAGCGGGCTGAGACGACCGTGGGGTTCGAGGCCCAACCGCTGGGCTTGCTGTTCCCGAATCGGGAGGGTCCCCAGAACACTTTTTAGCTGCCGGGGGCGTCCCCGTTGGGTTTGGGTGCACGCTTCGACAAAAAAATTCCCACTTCGGGACTGACGTGCTCCAGCATCTGCTGCCGCACCGTCGTTTCAATGCCTTCAAGTGTGTCAACGGCTTCAGGAGGGCTATTGCGATGCAGAATCTTGGCAATCTCGCGGCTATGCTGGGCTAAGGCGGCTTGGTCTTCGGGGGACAAGAGCTTTTGGGGTAGAGACTACCCTTTCATCTCAGCACAGATGCTGGGTTCTCGCAAAAATGAGATGCTCCCCAGCCTTCGATGAGTCTCTTGCAGTTCAGGGTTGAGCGTCGACCTTCTATAACTAATTGTTTTTTCCCTTATTAGGGAATCATAAAGCCATCCATCAGAACGATGAATTAAAAAAGGAATTGTCGTGAATAATTCAAAGCTAGTTTGTTTAAGTCTTGTACCCACGAGGAGATTATAAATACTTTCATTTATAATTCTAGGGACCGCTAGATCCAAGAATATTTTTCTATTTATCAAGGTTTTACGATTATTGAGATAGCATTCCAATACGATAGTTTCATCTAAATGAATATTATTTTTTGTGATATTCCGCAAATCTTTTACCAAGTCTTTCAGATGAAGAGGAACGCCACCCGTTAACTTTGATATAAATCTCTTGATAATCTCATCTTTAATTCCTTGGTGATCAAGAATTACAGAGATATCATTGGCCCTAAACCGATTTAACTTGACGTCAGATATAAATGAGTCAAATAAGAGCCATGTTTCCCTATCTAGCTTTTCACGACCTGAGATAACCACAATTGAATTTCCTGGTAGCCCTCTACTAGAGCCAACTGTTTCTACTAATCCTATTAGCCATGGATCCAGTATGTTTTTGTTGATATGATAGTCATCAAAAAAAAGTACTATAGGTTGATCAATAGCAGCACTTCTAAGTGCTCTTAGGAGTTCAAATGTTAGAACATCTATAGGGTTTTCAAGTAATTTCCTATCGTCTGAATTTACAATTTCTGACTTAATAAACTTCTTTAGGTCCAAAATCGCTTTCTGAAAGCCTTCTTGAATTTCTCTATCTTGTCCAATTCTATTAATATCAAGACGATTTTTTATCTTTTCCTTCTCAGGAGATATCCTAAAATCATTGATGTTGGTAAGGTTGCTACCGATTAGATCAATATACGCTTCGGGTATGTCCGTGGTATTCTTTAACTTTGACTTTAATCTGATATAGGTTGAATAATGTTCTTCAAAAATTGGATTTGATACCTCAGACTCTTTCAGATCTTCATATATCTTTTGCATTATTGATGGAATATCATTCAGATCTTTTTGGATTAGGGATGTAAATGAATTATTTTCAAGGGCAATATTCCTGAACTCTTTTAATAAGAATGTTTTCCCAACCTTGCTATCTCCATAAATGTTAAAGACATAGAAGCGCTTTCTGGTAGACATTCGAAGATTATTACGAAACCTTTGTCGATATCTATTTCGCCCTGGAAACTCTTCTAGGCGTCTTATATTAAGTAAATCTCTAAGTTCCATTTTCGTGGAAGGATAATGAGGCTAAAAATCAGTGTCTTGGCATCGGCCATAGCTTTTTGAATAATGTTTGCTGGCCATTGAGAAACCCTAGCAGCTGCTCCGATTCCACTGAGTCATCGGGAAACACGGTGACTAGCTCAAAATATTGCCGGGTGACCAAGGGCATGGGCTTCTTAGGGTTCTCAGGATCCTTCACCAGTCGTACTTTGGGATACATGCGGTGCCACAGCCGCCCGACATTGCCCATCTGCCCGGTAATAGACGAGCGGTAAATCGATCCTTCCGGAATGCCGACCGACGGAATCGCCTCTCGATAGGGGCCATGCAGCCATCGCACCGCTTCACAATCTTCCAGTCCGTCGGTTTCGCGTCCCCACACCTGCACCTTGTCTGGATGCCAGGCCTCTCGCCAGTTGGCATGGGTGTCGAGTTGGGGCGTCCTGGTCTGCAGCTGCATCCATTCCTTGGCCGCCTGGCGCACTTCGGCAATGAAGTCGCCTACTTTTTCTAGCTTGCGCACCCGCACATCTCGCACTTGGGACCGCTTGCCCAGCCATTCCCAGTGGCAACCGATTAGCGGTTTGTAGCCCTGATCATAATAGTCAGGGTAAACCAGACGATGGTCAGCCCGGCGCCAGGATTTGCCAAAGCCACCGAAGACCATGGCGAAGCGGGTCAGGGCCTCGATCAGTTTAGTCAGGGCTTGCCGCTGGGGCTGAGGTAGGTCTCGGGTGAGTCGCCAGAGCAATTCTCCCTCCACGGTGTAAGTGGGCTGACTATAGGAACCTTGGCCAAAATCATCCAGCTCCAACTGGGTGTCGAGAAAGGCCATACTCAGCAAGCCCACAGTGGCTCCACCCCTAATGCCACCAAAGAGATCCTGGACCAGACCTTCAGCCTGGTCGGCATTGGTTAAGCCGCCAAAGATACGCAAGGCATGGCCCCGGATGGCGGCGCGAAAGACATTGGGGCGAAACTCTCCAGTGCCATCTACTAACTTGGCCGCCTGACCCTGACCTTTGAGGCGCGTGCGGTAGAGAATATCGCCGCTGCGTTGTTGAGGTTGGCCATAGCCAGCACTGACTCGGCAGCCCAGCCCCAGGGACAGCGCCGTTTCCCAGATGTGCCAGATTTGTTCCCATTCAAGGTCATCCAGGGGAGTAGTGCTGGAGATGCCGACTATCAGCTCGGGTTTATAGAGGGAGATCTGTATGAATGCCCCGCCTTCCTTATCGTTCGATTTGACCTGCCACTGCTGCTGGGGATGGACAATATCCACCAGGTTCTGAGTCCAGCGGGTGTCGGTGGGGTAGCCGCCGTGAAATCGTAAAATACCAGGGCGAAAGTCATTATTTTCTAGTTTTTCGCCGCAGTAGCGATCGCATGTCCCCAGTTTTAATTCCCCGGCCCGTTCCAATTGGTGAGCCGCCTGGCGAAATACGCCCTTCATGCTGCTGCCGGGGTAAAAGGGCCAACCCCTGGCCCCAATTACCGGACGAATCACCCCGTCGTCTTGACCGCTATTGGTAATGAAGCGCCAGCTCAGAGCATAGGGGCGGGTTTGCACGTCTTTGCCAAAATTAGGCGCATCGGGATAGGCTTTGTCGACCCATTCATCGGCCCAGCGCTCGGCATCTTGTTCCAAGGCCTTGGGAATCAGTCGCTGTACCTGGCAGCGCCCCTCCACCTGAGCCCGAAACATCAGGGGAACTTTGTTGGCGGCATCGGTGAGAGTAGACATGGGTCAATAGCGAGAGTTAAGGGATGGACTGGGGATAGAGGCCAAACTCGGCATGAAGAAAGTGGTAGGGCGGGCATTGTCTCGTTTAGAGTTTGGGCTGATGGTGATTGAGCCAAGCAATGCCAGCCGTTGCGAATAAATGATGGGCAAACCAAGCCTGTCGCATGTTGCTGAGGTGACCTGTGATGGGGTTGTCCATCCTACTTCTCTAAAGGACATGGAGTTGCGCATCTACTTATATCGCTGGGTCCACCAGACCAGACAATCGCAGAGTTGGGTCAGCACTGCCAGGGCCAATCGTTGGTCTTCTAGAGTTAACATTTTGCCGCTGGAATCTACTGGAATTTCTCCCCAAAGCTTTTGTGCCATTGCTTTAGGGTCAGAGTCGTTGGGAAGAGTGACATCTGCTGGACCCAGTATGTTAGCCAGTATGTCCCAGGTGGCTTTCCAATACCGGGACTTTTTCTCTTGTTTCCCTTGATGACGCATGTGTTCGCCCCAAAACCGTTCCAACCCATAGGCGACTGATTCCCGCATCTTATAAGATTCACGCAGACAGGCGTCACCTTTTATATCTTTATCGTTATCAATATCTAGCGCCTGAAGCACCAGCCACTGGGCTTCTCTATCGAGTCCGTATGCTTGCCATCCCATAGATATTTCCTCCTCGCATTATGCGTCTGCATCGTCTGGCGTATCGCCAAAATAGTCGCCAGCCAGCGTCACTTCACAGTGACCACAACCGATAGATTCCAAGCCCCCGAAGTACAGCTCTCGCAGGGTGCGATTTTTAAAGGGTTTCCAGCGGGCACTGCCATCTGCGGAAGCGTCCGAGGCTCTGTCATAGTGCGGAACGCTGTCTTTTACAGCAATCGGAAAGATCAAGATACTGTCTTCGGGCAGTGCTTCAAACCCGAAGAAGTTTTCTACTTTTTTGACATCGTCTTCTAGCTTGGTGCGGGTTTGACGATAGAGCGCCATGTCATGAATGATGCTGATGTCTTGATCATCCACAACCACTAAGTTGTCAGGCTGGATCTGCGAGTCTTTGGGAACCCAGTTAGACAGGTCAGGCGTTTCCGCCAAATTATCCAGAAATCCTAAGTTGAAGAAGAGGCGATCGCGGTGTTCCCGCAGCTTTACCGGATATTGCTTTGGTTGGCCATCAGCCGCTGCCTTGGGACGAAGCACTGGCTCAGGCTTGCCAGTAATCTGTTTGTAGCGACGCAATAGTCGGGGACAGCTCACCCAGACCACCGGCTGTCCTGGACAAAAGACTGGAATCCATACCAGGGACGCATACTCAAACTTAACCAGTGCCTCTGTGGTGCCGCCATCTTCCTGACCGGTGACGGCATGATGACCATACCAGTGATTTTCGTTCACCAGCTCAGGCACTGAAATCGATTGCTTCTCGGCTTCCTGCTCTAGCCATTCCAGCCGGGGCAACCGTTTCTTTGGGTCCTCCGGACTGCTGACTTTACGGGCTGTCGCTGCTGGAAGGTCAACGCCTGCTGCCTTCAACGATGCTTCTAAGTGCTGTTGCCGTCTCAGGCGCATATCGGCGCGAAAGCGACCGCGAATGGAGCTGCCGGGGATAATTCCCGTCTGGGTGAACTGGTCGCGAAAGATCAGATTCAGGTTACCGGTTTCTTCGCCGGCGCTGGCCCCCACATGGAGCGGGGCCAGGGTTTCGATGATGCCGTAGGCTCTGTGATACATAGGAAAACGAGAAACAAAGAACGACGCAGAAACACGTAGCGTGGGTTAGGCGCGATCGGGAGGGAAACCGGCGCTGGGGGCCGACATCAGAGCCGTAACCCACGGGGCGCACACGGGAACACAGGAGAATTACGGTAGCGCCCCCGATACGGGCAACGCCAAGCCACAGCCCCAGCGTTTGAGAGAGGGTCCCTCGCGGGGGAACCAGTCCAGGGGCCAGTCTTGCCAGGTGGCATGGTGATCGGGGAACGTGTCTTGCAAGACATAAACGCTGCCAGCCGGGACGGCGTAGCGACCTCGCGACAGGACCTTAGGCTGGTTAGGTTGATGGACATCTTCTCCCTGCTGGTTCTTGCGGTTGCCCAGGCGGTAGCGAAACGTCGTGGGACGTTCCGTGATTAACGTGGCGACATCCCAGAGTTTGGCTAGGTCTCTGTTGATCTCTGCAAGCTGGTGGCGGCTCTTGTCGCCTTTCTTCAGCAGCCTGGGACTACGGTAAGACAGACGGTTTGAGCCCCAAACAGCCGGGGTAATCAAGGCAAAGCTTTTGCCCAACGGATGGGATAGCAGCTTATGGAGTTCAGAACCTGCTGAGATCGGGTGACAGGTGAGCTCTACCATGTGTCCTTCACCGCCGAAGCGGTACCAGCCGTTTTCCACCGAGAGGTTGGAGAGATAGACCAAACACGTCTCAGGATGCATTTGCACCCCATTTTCTAAGAACAGACTGCCACGTTCGCGATCGGCATCGACCCGGCGTTCGTTTTCCATCAGGTAGGGATGGAGATGGGGGGTGTAACGCCAAGGATCACCGTAGACAGTCGGCTCCTGATAGTCGGGTTGCCATTCGTTCAGTTTTTTCCAATCGTTGATGGCGACCCAGGTGCCTCCTTCAGGTTTACCGAGAGCTTTATCTGAGATAGGTTGCCAGCTCTGGCCATCCCACTCCAGGCGATTGACTAACGATCCTTCAGACACGTCGGTTGCATCGTGCTGAGGCTCTAGCTTGGCCAGACAGTTCATGGGAGTAGGAACGTAGATATTTTCTCTATCGGCGGTGTGGGTCCACTGCCAGAAAGGACCCGCCAAACAGAGGGGCTTGAGGATGTCGTCTAGGGCTTGCTTACTCTCGGCGTGCTGAGCGTAGTGGGCCGCGATTAAGCCAGATAAGACGGCGGTACTAGGAGGGAATTGGCTGCCCGATCGCCCCACCAAGTTTTCCGGAGATAGAAATCGCCCGGTACTGCCATAGAGCAGACCCAACGGCTGGATGGTGATCAGGTATTGAAAGGGCGGTAAGGAGGGGCTATCGGTGGTCATAGCATTTTACGGGTGGCTGCTTAGGCGGCGAGTTGGGCCATGTCTGAGCGATTCAGGTGAAAGCCGACTTTGGCCAGGTTGATGACCCAGGTGTTGAAATCTCGCAGTACAAACCTATGGGTGTTAAGGCGCTGCCAGGCATCATTAGAGCTATCGAACTCCGGCATGTATCGCTGAGGGTCACCCAAGATGCCGCTAAAGAGGCGCTTGCCGGTGTTGGGATCATCCCGGTTCCACCAGTTGGATGGATGTCCTAATAGCTGACGATACGGACGACCAAAGTAAACCTCGATCAACCCGAGCGCTACATCAATCTGGGCGCCATGAAAGGCGTGGCGAGCTTCGAGGACAGCAATATCGTTATAGATATGGGTCCAGCCTGGATCGTTGCAGGTTGGCATTAACCCGCTTAAGTCATGGGTATCCAGAGAATCTAGATCCTGCGATCCCGAAAAATCACCTTCCAACAGCCACCAGGGACAGACCCACTCCAAGTGATTACCGCCGTTGAACAAAATGCGAAAGGCGATGCGGTCTTTGCCGTGCCTCTTTGCCGACTTCTCTGCTTCGCGGCAATGCTGCAACACATCTCGCTGGGGCACCTTGGGAGCCGCCCACACAAACCCAACGCTCACCGTGATGGGTTTTGAGTCGTTATCAGAAGTCGGAGGAGCATTGCTCACCGCTGCCGAGGGGCGAGTCAGATCAGGATTCTCCCAAACGTGAGACTTAAAAGTACTGAACCAGTGCAGACACTCATGGGGCTGTATTTCTGCCCGTTCCCGGTAGAGCACCCCGAGAAAGTCATCGCCCCCCGCGTAAATCATGCGGCCATTGCCAGGCAGAATAGGCTCGGTTTGACCATTTCCATCCGCTTGGGGCCATTCGTTCTGGTACAGTCGTTGGCCCCACTGTCGCATTTGGCAACTAAAGTCGGTGTAATCCTCGTCGCTGTGGCAGTGATGGGCCAGATAGTTACCGGCGTTGTCGCCGTCGCCCATGAACCAGCCCGTCCAGTATTCCGGCTCTAGGGCTTGATTCGCTTTTTTATACTTGCGCTTGAGGCGATTTAAATCAGTAAACCTTTGTGGATCTAGTTCATGAGCAATGGCGGTGATGGATTGTAGCTGATCGCGATCGAGGTCATAGTCTCTGACTTGGCTCTGGTAGTTCGTCTGGATTCTTTCAGAAAGGGCTTTGTGGGTGACTAAGCGCTTGACCAGCTCTGGAATGCTCAGTTCCTCGTCTGGATCGACGAAGGCAGCACCGTACTCAATGGCTTTCGTCTCAGGATCAGCAGGCGTGAGTCCGACGGCTTCTATGAATGCCTGACCCAGGGTTCGGCTCAGGGTGGCATAGAAGGCCTCAATTTCAGTCTTTTGCTGCTGGTAGTTGATGTCGCGGGGGCTGAGATACCCTAGCTTGGGCCAGGCGATGCCATCGGCCCCTGACAGAGTTGAGCTTTCACCCGTCCAGTTGACGCCCGTCCAGTTGCGGGAGCGTTTTTTCTCCAGCACTGCCGTTCTCGCGGCTGGGATGGAGCATCCAGTTGCGATAAAGAACTCCCAGGCATACTTTGCCCACAGTCCCCAGGACCGTTCCCAGTAGTAGGCGTCGGATATCTTGCATTCGATCCACTGGCGGCAGGTATCTACCACACACTGCCAGGCAGAGAAGAAAGCCGTTTCAGTCTCTTCCGGCGGCACGTTACCACGAACGAGAATCAGATTCGGCATGCCCTGACGCACATTGGGCAGGGCTGGAGAGATCACAGAGCACTCTGGTTGGGCACTGCAAATCGCCCAGGATAAGAACGAGAGCAGGTAGGAGCTGCCATAGAGGTCTCGCAATTTGCGGGAGTTTTCAATAAAGCCTTGGATAGGAGCGAAGGTAATAGCCGTGTAGACGGGCTTAGACATACCAATAGGGGAAATAGGCAGTTAACACATAATTGCCCACCAACCTAGCCGCGAATGCTGGCAATTTAGGCAGATTTAATGTTTCTTTTGAAATCAGGAAGCCTGGCGCTACGAAGTTGCTCTAATAAGCTTCAGCCCTAGCAATCTCTGAAAAGCTAGGGCGTAGCGTGGGTCGCAGTGCGACCCACCGACCCACGATCATGGTGCGAAGGTTGATGCAAAGTGCCGTGGGTTTCGTGCCTCAACCCACACTACGGTCGCTCTATAGGAGCGAATGCTGATTGAATGACTTAACCCGAATTCAGGTTATTGTTACTGGCTTCTCAAAGCTTGGGTAATCTGAGCCGCATCAACCACTGCGCTAATCAGAGTGCCGCGCATATTGGACATGATGTAGTTGAAATCTTCAGGAAACGTGTTGACCGCTTCGATTATGCCCTTGACGTAAATCACCAGCACCGTTGGTCGGCGCCGTTGGGTGAGTTTCGCCGCCGCTTCCTTGACTAAAGCTTCCTTGCGCTCGGGCGATAGCGACGGCGTCATCAGATCCAGCACAAAGACATGGCTCTCAGGCCAGGCTCGTTCGGGGTCATAGAGAAACGGGGCCATCTGGAATCCGCGTGCGTCTAACAGGTCATACTCCGTGGGGTATCGTTCCGGCTCACCCGCCACAAATACATAATCCACCTGAGTACGGCCAATGGCGGCTTCTCGACCCACCATCTTTTTGATGTAGCCGATCTCCTCATCTACCTTAGTGGCAATCTGGCGATCTACTTCTGAACGCACCTGTTCCGCCACTGACAGCTTCACCTCTTGAATCGTCTGCTGCACTTCCTGGCGAGTGCGGACGCCAACGAAGGCCAGTAGAATGCCCACGACCACAAAGATCGTGCTGATGGCACCAACGAATAGGTTAAAGCTGGTGGTGAGCTGAGCGTGGGACTCTCGAAAGAGCTTAATCAGGTCAGTGGGGGTGGCGGGGTCAGACGTTGCCTGGGCGATGACAGCATGAAGCAAGACCATAGAAGCCAGTGGAGTTTAATGCACCTCAGTATAAATCTCGGGTCCGCCCTTCTTACATAGCCCCTCTCATTTTGGGAAATTTGCTTTCGCCCTGAGGAGAGCCTGGAGCATGGGTCATTTCCCAGGCCGCAAACAGCTATTCTCTGGCCCCGCGAGGACCCATGCTCCTCCAGGAAATAGCTGCCCGCATGCCTGCCGCAAAGGGCATCCAGAGAACCATGGCATCCTCAGAACGGATCGGCTCCCCTGCTCCCCTTGTGAGAGTAGCGGCATCCTAACCCCTGGGCTATGCTGGCCCCATAGCGATCTCCCTCCCCCGACACGCCCCATGGTGACCATCCCGCTTCCCGATGCCCAGCTGATGAGCTTCGACGAGTTCATCGCCTGGAAACCCGACAACCAACCCTATGAACTCCACCATGGCACCCCCATCGAGATGCAGCCCACCGGCGACCACGAAGAAATCATCGCCTTCTTAAATTCAGTGCTGGTACTGGAAGTGCATCGGCTGCAGCAGCCCTTGATGCTGCCCAAGCAAGCTCTGGTCAAACTCCCAGATGAAGACACCGCCTACCTGCCCGATGTGTTGCTGCTGAACCGCGAGGCCTTGCCCCAAGAACCCTTGTGGAAGCGAGCCTCAACCGTCACCCAAGGAATATCAGTGCCCTTGGTGATCGAGGTGGTCAGCACTAACTGGCGCGATGACTATGGCAAGAAACTGGTGGATTACGAGAGCCTGGGGATTGCCGAATATTGGATCGTTGACCACTTAGGATTGGGCGGACGTCGCTACATTGGCTATCCCAAGCAGCCGACCCTCTCGGTCTATCGTCTGGTGGATGACGAGTATCAGGTCCGTCAGTTTCGAGGTCAGGAGCCGATCCAATCCGGGCTATTTCCCGATCTAGCATTAACGGCAACAGCGATTTTTCGAGCTGGGCCATGAGGCTCGGCTCCCCTGCTCCCCTCGTAGAAGTAGGGGCTGGGGGAAGAGGGAAATTGCGAGGTGTCGTGCCTCGAGAATCTGCGGAATAGCGTAGACCTCTACCTGGATTCCGGGTCGCGCTGACGCTTGCCCGGAATGACGGTCATGCTTTCCAATATTGGTTTAGCCGTCACAGGTATCACACTCCCGTCATTCCCGCGGCGGCGGGACTCCAAAGCACCAATCTCGGCAACGACTCAGAGCCCCCTGCATTGCAACGTCCCTTAATGTTGTTACAACGCGACTTGCTTTCGTTACATCAAAAGCTGCTCACGTTCGACCGCGACTTGCTTTTGTTACAACGATAGTTGCTTTCGTTACACCAAAAGCTGCTTTGCATCGAACAATAGTTGCTCACGTTATAACAATAGCTACTCACGTTGTAACAATAGTTGCTCACGTTGTAACAATAGCTGCTCACGTTACAACGAGACTTACTTTCGTTACACCAATAGCTGCTCTCGTTACAGCAAAAGCTGCTTTGCATCGAACGAAAGTAGCTCACGCTCGAACAAATCTACTTCTGAGTCTAAGCCCATCAAGTCACCAAACTCCCTACCCAGCCCGGCGTCTGGCCCGACTAGCCACCATCAGCGCCCAAGCAGATGCTGATCCCCCCTGAGGCTTACTCCAAACGCCAGCGCCTGACCTCAGTAAACTCCCCCAGGTCCACCCTGAAGCCCGCTTAAAAGTTCCCGAGAACTACTCAAGGCTCTTTAGGTTTAAATGCCTAGAGTATAGGAATAGTTCTAACGGGATGACCTACATCAAGGGCCAGGCTGCATCGGCAACACCGACATCAGGGTGTATATCATTCCAGCAGAGCTGTCATATGTTCTTTAGCAAAAGGAGTGCATTATGGCACGCCGTAAACGAAATTCAGCCACCCTTGAACAGGTAGAACGCCGTCTGGAAAGCATCCGCTCCATCGCCACCGATCTAGACCTGGGCGGCGGCCTCAGCGTCCAGAACTTCGCCATCATCGTCGGCGATCTGGCGGCCAAACTGGCAGCCTACAACACCGCCCTCTCCAACATCGACAAAATGGCCGACGATGTTCGCGTCGCCGAACAAGCCGCCAAAACCATGGCCGAGAATATGCTGTTGGGCATCGGCAGCCACTATGGCAAAACCAGCCAAGAATATGGAATGGCAGGCGGGAGCCGCCGTCGAGGTTATCGCCATCCGCAGGTGGCAGATCCGGTCCCTGACCCCGTTACCATACCGGTGGTTGAGCCGTCCCAGAATGGGGCCAGCGCCGAGCCGGTTTTGGTTTAGGGCCTTGGCGTGATGGTTTGTTGAAGCTGTCACTAGATCACACCTTACTTACCCATTAAACCCCAGAGTTCTGAATGAACCCTGGGGTTTTAATCATGACGCCATATCGAAGCAATGCTGAGATCATCGTCAGCGGCAATCGTCGCCCGCCCCAATTCACTTCCTACTATTTTCGACCAGACCTAAGTCTGGATCAATACAAATGTTTTGGTTTGGGAGTTATTTATTATGTGTGACCTTTATGTAGTAAAGCAAGGCACCTGCCTGCGTAAAGAGCATGGACGCTTTATTCTCAATCCGCCTGAAGATGACGGCTTAGAGATTCCTATTCGAGAGATCGAGCGCATCCTGCTCTTTGGTAATATCCAGCTCAGCACTGCCGTGATCGGCACCTGTCTGCAGCAACAGATTCCGGTGGTCTTCCTCAGCCGAACCGGCATCTATAAAGGACATCTCTGGAGTGCTGAGCTTAGAGATTTAGAGGCTGAACGTAACCAGTTCCTGAACTATACCGATAGGACCTTTCACTTAGAAACTGCCCGAGCCATCATTCGCGGCAAGCTCGTGAACTCCAGGCAACTCTTACTGCGCCTCAACCGCAAGCGTCACCTGGAGACCGTCGCCAATGCTATTAGTGGAATTCAGCGAGACATTAATGCTTCAGAGACAGCGGGCTCCGTTGACCAACTGCGAGGCTACGAAGGCATTACGGCTGCTCGCTATTTTCCAGCCCTGGGTCAGTTATTGATCACCCCTGACTTTACCTTTGAAGAGCGCAACCGCCGCCCACCTAGGGATCCTGTCAACTCCCTACTGAGCTTTGGCTACACGCTGCTTTCGAACAATGTCATGAGTCTCATCCTGGCAGAGGGCTTAAATCCCTACCTGGGCAATCTCCACCGCTCCGATAAAAAACTACCGGAGCTGGTGCTCGACCTCATGGAAGAGTTTCGCTCCCCAGTCGTGGACACCCTGGTGGTGACGCTGATTAATCGCCGCACCCTGCACCCCGATGACTTTACCTGGCCCACCGAAACCGGTGGCGTCTATATCGCCGATGCCGCCCGGCGACGGTTTATTCATGCCTTCGAAGCCAATATGAACCAAAGCGTTAAACATCCAGATGTGCAAGAACCGGTGACCTATCGCCGCGCTATTCACTACCAGGTGAAGCGCTATAAACGAGCCCTGCTGGAGGTTATACCTTACCAACCTTTCGTGAGGGCGGCCTAATGCTGGTGCTGATCACTTACGATATTCCCGATAATAAACGCCGCACCAAGTTGGCAACCTTTCTAGAAGGCTACGGACGACGGGTACAAAAAAGTGTGTTTGAATGTTTTCTAACCCAAGCAGAAATGCAGGAGTTACATCGACGCATTCAACGCCGTGTTAATCCTGATGAAGATAATGTGCGCTTTTATTGGCTTACCCCTCAGTCCGTTGCCAAGAGTCTGGCCATTGGCAGCGACCCGCCTACCCCACCTCCCAATGTTTACATCATTTAAATGCCTCCCATCGACGCACCCCTACCAATGGCTGTAGCTCCCATTCTCTCGTGGAGGTGCGTCGATGCCTTGCACCATCAGGGGTTTGAGCATTGGTTGGAGGCTGAAATGCTCGATTTTGAGCATGATGGAGTATCCTGTTTAGCAGGTGCGTCGATTCAACGGCTGAAACCCGCTCCGGGCAAGGCCCCCCAGACGAACTCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCGCTTGAACACCCGGATCAGTATCCGCAGCGATCGCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTCACAGTCCTCGCTGAATTCGCTTCATTTTGAGCCACTCACCAACCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTCAGGGAACAAATTGATTTTGCCGTTCACCCAAATTGCGGCATAGATTACCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTCTTTATGCTCTGGTCTGTAGAGCTCTGGATTCAGCATCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTGATTAAGTTCGGGAACACAACCATCTGCAGTGTTATGCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCCTCGATGTCCTTGAAGTTTTATAGGCTCTTTAGTATCCGCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCTTCTGCTAAGAAAGGATCCATCGTCAAACACGATAAACCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGCTGACGTAGCGCAAACCATTCTTCAGCCAGGAAGCTTGGCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCCGTAGGCCCCATTTGCAACTGCGCGAATACAGGATTCCGTGCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACAGCAAGGGTTTCAGCCATTCCTCTCCCTTTGCTATACTCTTCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTCGGGTATCAGTGCTGCTCCTAGTGCCTTAACCCCAACTCAACCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTTTGGAAAGTAGTTTATATAAATTTAGATGACTCCGAAAGCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTAAATACGGGTGGACCTTCAAAGATTTTGATTCTGTTGACCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTTATTCGAACCACTTGGATAAAGTCAACGAACAATTGACCCCCCACCGATTGGGGTTAATTCGGAATAGTTGGAAACGCGGGGAGCAGTCAACAGGTTGGTGAGTTTCTCATGTATGTTGCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCGTAACAGAGGTGGTCTAAGCTCTAAAACCCTTGCTGTGTAGGAGTTCCCCCACCGATTGGGTTTAATTCGGAATAGTTGGAAACAGTTCCTCCAAAAGATGTTTCTCAGAGTGTGGCGACCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACAATAATCAGTATAAAACTGCCCATTCGTAATACAAACACCCCACCGATTGGGGTTAATTCGGAATAGTTTGGAAACCTAGTAATCCCCTGTTTGTTTTTGTAAGGGTAAGGCCGGTTGCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGAAGGACGCATTATTGATCTTACTGGCGCAACCAACCCCCACACCGATTGGGTTAATTCGGAATAGTTGGAAACCTTCGAAAGAAAAGACCTTTTCGGTTTCTATATCTGAATCTCCCCCCACCGAATTGGGTTAATTCGGAATAGTTTGGAAACAAAGTATCTACAAACCCAGCGGCGACCGCCCCCGGGCCCCCACCGATTGGGTTAATTCGGAATAGTTGGGAAACAAAGCTTGGGCCAGCTCTAAAGCACTGGCATCAACTTCCCCCCACCCGATTGGGTTAATTCGGAATAGTTGGAAACTGTTCAGGGTGTTCAATGGTAGTTGTTTTAGTTAGCCCCCACCGATTGGGGTTAATTCGGAATAGTTGGAAACGTTAAGTAAAAATTTTATTGAAAGAGTTCTTACCTTAACCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCAAATACATCCAGTCATAGAGGCGATTGTAAGGCAGCCCCCACCGATTGGTTAATTCGGAATAGTTGGAAACTGGCTGCATCGTCGCCTGGTGAAGCTAACGGAGCAAACCCCCACCGATTGGGTTAATTCGGAAATAGTTGGAAACGGGGTGGTGACTAGCTCGTAGCAAGCAGTCAGCTCCCCGCCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGGACTTAGGTACAGGGTTGTTTAGATGGACCTATTGGATCGCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTTTTCCAAGATTTGGCAAATCAGCGGCGTGTCGTTGCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACAGATGTCACAACAAACCCTGAGGCCGCAGCATACAAGACCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACACTTGTCGGATCAGTAATTTACTGAGATCTCATCGCAGCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTGGGCCGGCGACTTGGTAGAGGTAACGGGGGTCCCTCTTCCTGTTTCCCCCACCGATTGGGGTTAATTCGGAATAGTTGGAAACCCACTGAAAAAGTTAGAGCTGTTATTGTTATAAACGATGGCCCCCACCGATTGGGTTTAATTCGGAATAGTTGGAAACTGTGGATTTAATGCTGCCGGGTCTCGTTATTGTTGTGAATACCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCCGTAATGGCAATTTTGTTATTATCTAGGTAATGAGAAAATTCTTTCATAGCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAAACAACTCTTGGGGATCGAGGAGTACGGAAAATGCTTCATCCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTCGTTGCCGATATGCAATCGCAGCGGGCAGCTCTTCTCCGTCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGGTGTAGCCAGGATTAGAAGGGTGGTCATTGGTCAAGCCCCCACCGATTGGGTAATTCGGAATAGTTGGAAACTCACGTCAACCCATAAGATCGTGTCCACAGATCCATTCGCCCCCCACCGATTGGGTTAATTCGGAAATAGTTGGAAACCCAGACAGTTGTGCTTTTTGACGCTAACCGTGCCAGCCCTGGCCCCCACCGATTGGGTTAATTCGGAATAGGTTGGAAACGACTTCCCCCAGCGGGACGCCACAGCCTCTTGAGCTGTGCCCCCACGATTGGGTTAATTCGGAATAGTTGGAAACCTATGCCTTCTTCAGTTATGGCGACGCCATGTTCCTGACCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTACTTCCTCTAGTTCAACATATCCCGATGTAACCAACCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCCTCGCGCATCCACAGTAGGCTTTAGCAAATTTACCTCGATTGCCCCCACCGATTGGGTTAATTCGAATAGTTGGAAACAACATAAAAATTTGTTTTAGTTCTTACACGCCTCAGTTTCATGCACCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACACTGAAGCCTGTCGGGTGGCCCAGCGCATCCACATGCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCGAGAGGCAGGACCAGCGATTGCAGCAGCAGGAAGAGGAACCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACACGTATGGCCGGCCAGCAGGTTCTATGTCTATACCCCACCGATTGGGTTAATTCGGAATAGTTGAACAAGATCTCAAGTCGAGAGATCTTCAACAAATACCAAACTAGCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCCACAGTCCCTAGGGGTTGAGGACGGAGCAGGTTTTCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACATGACTGACGCCCGGGACTCACCCGAATCCCGCAAACGAGCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCCGAACAATAACTGTCAGGTCACCAAAGTCAATGTTGTAGCCCCACCGATTGGGTTAATTCGGAATAGTTGGAACTCAAGGCTATCGATTAAAATGCGCTCGATTTTACCCGCAGCCCCACCGATTGGGTAATTCGGAATAGTTGGAAACAACTTTGAGTCCACCAGGATACCATAACAGGAGCACTAGGCCCACCGATTGGGTTAATTCGGAAATAGTTGGAAACCAGTTCTTTTTATAAAAAAGTTCTCACACCATAAGAGAAAGTTCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGTGGTAGGAAAAGTCGCAGCAAATGGCGCGGCACCCCCACCGATTGGGTTTAATTCGGAATAGTTGAAACGTCTCCGGGTTTGTAGGGTTTTTCCTTCCTGTTATCTATATCCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAACGTACAAGCAGCGGCTTCATTTGCAAGTTTACTGACTTCACCCCACCGATTGGGTTAATTCGGATAGTTGGAAACGCATCATTCCATAGTCGATCTGGTCAACTGCCCATTAGGTTAGGCACCCACCGATTGGGTTAATTCGGAATAGTTGGAAACATGAATTCCTGCTAAGTCAAGATTTGGTAGTTCCGACAGGCCCCACCGATTGGGTTAATCGGAATATTTGGAAACCAAACGATCGAAGTTGCTGATATTTCAGCGTTGAAAGCGCTCCCCCACCGATTGGGTTAATTCCGGAATAGTTGGAAACGGTCGTGATTGGTCGCTACGCGGCTGAGGGTGCTCTTTACCCTACCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACATAGGCAAAGGAGAGATCAACCCAAAGAGGACGTCGACCCCACCGATTGGGGTTAATTCGGAAATAGTTGGAAACTCAGCCCGCGACGAGCGAGCGAGGAGCACTATGCGCAGTACCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCGGTTGATGCCGCCATGGAAGGCGGTACCATAGTTTCGTTCCCCACCCGATTGGGTTTAATCGGAATAGTTGGAAACTCACCTGAATAGTACCCAGAGATTGTGCCTGATTCAGTCCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACACCTGGCATCGACACCTGGCCTGTCACTACAACAACTGGCCCCACCGATTGGGTTTAATTCGGAATAGTTGGAAACTCTAAAAACTGACCCTTCCGTCATCGCCAGCGTTTCACCTCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACTGAAAATCCAGAATCATGAGGACACTAAGCAACTTGTCCCCACCCGATTGGGTTAATTCGGAATAGTTGGAAACGACTGGCGTTTCCCAATGGGCCGAGCATTTTCATGCCGGTTCCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGGGAAGTTCCTCAAAAGTACTATATGGATTTGACTCAAGCCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCAAAATCCCCGGTATTCTTCTTCTTGGATGTGAACTTCTCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGCCCTCTCCCGTTGGGGTTGGCGCATGATATATCTTGGCACCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACATGGGGGAGCTAGGCCAGGAGCCGGTCGAAAACCTAAATATCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGTCAGTAACTGAAGCTTTGATTGAATCCCCCTTGTTAGCCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACGATTGTTAATTGGAGTAGAGAGTCCACTTTCTGCGGTTTGCAACCCCACCGATTGGGTTAATTCGGAATAGTTGGAAACCGAAGAAAAGAACGAGGGCGGAGGGCGGAAGAACGAGGAGATTAGAGTGAAGGTGCTCACAAATGATGAGCCTCTCACCATTGGACTCTTCCGTCCTCTCTCTTCCCTCTTCCGTCCTTCGGACCATGGGCGGAAGAACGAGGAGATTAGAAGAAAGATGCTCACAAATGATGAGCCTCTCACCATCGGACTCTTCCGTCCTCTCTCTTCCCTCTTTCGTCCTTCGAAGTTTGAGAGAGTAGGTAGGGTGGGCAAAATCAGGATATAGCAAGCCTAACTGAATTTAGAATGAGAATCGCTTACAAAGCCTATAGTCTATGGAATGCTGTTCGAAATTCAACTGTGATTGCTATAGATAACCCTCGCTGGTGCCTGTAAGCTTTGTTTGCCCACCAATTTTTTCAGCGGTGGGCATTGTAGTTTGAGTGTGGGTTAGCCAAGATTTCGGACAAGATAATGCCCACCCTACGAGCTCACTTTTTAACCAAATTCCTCCCTCTTCCGTCTTCTCTCTTCCGTCCTTTCAACTCCGATTGGGTTAATTCGGAATAGATGACGGCTCAAAGTCCCTCTCCCGCTCTGGGAGAGGGATTTAGGGAGAGGGAAAACTCAGCTATCAAAGAGCCTTCCTCCACGGAATTCGCCCCTTCGCATACCAGGTGGGCAAGCCAAAGATTGACCCTACCTAGCTAAGCTACCGATGCTGGGCTTACCCACCCTACAATTCCTGGGAGAGGGATTTAGGGAGAGGGAAAACCCAGCCATCAATGCGCTTTCTCACGCTAAGTTCGCCCTCTATCCCCTAACCCCCCTACGACTGCGCTCAGGGCATCGCTTTCTGCCAAAATGGGCGAAAGGGGAACCAGACCCATCAAAGACTACTCCCAACATGAGATAACCCCTTATAGAAAGGGCATTCTTACCCAAAGAACACCACTCGAAAACCCGCCCAATGACCTCCCATCCCACAGAAAAATGGGACATCCCCGAATCCCTACGTCGTCGCATGGTCGAAGTAGCCCGCGACCTACGACAACAGCAGACCCCATCAGAAGAAAAACTTTGGCAACAGTTACGACGCAAGCAACGCGGTTATAGAGTGCGGCGACAACAGCCTATCGGTCCCTTTATCGTAGACTTCTACATATCCCAAGCTCGACTCGTGATCGAAGTTGATGGTGCCGTTCACACTCAACACATTGAAAAAGACAAACAACGGCAAGACCTTTTAGAAGAACTCGGATTAACCGTTCTCCGCTTCTCTACAACCGCAGTAGAGCAAACCTTATCAGAAGTCTTAGAGCAGATCGATACTTACGTTCAAATCCTGACAACTCAGACAAATATTTAGTAACCTTCAAAGCCCCTCTCCCCTGGTTGACTGACAAAAGATTCTGCATTGGGCGCGGAAACCGCGCCCTTACCAGATTGCTGTAGGGGGCAGGTTCCCTGACCCTTTGGATAGTCTGGGTTCTAGCAGGTTTTGTCAGTCAATGAGCCCTCTCCCGCTCTGGGAGAGGGATTTAGGGAGAGGGAAAACTCAGCTATCAAAGAGCCTTCCTCCACCGAATTCGCCCCTTCACATACCAGGTGGGCAAGCCAAAGATTGACCCTACCTGGCTAAAGCTATCGATGCTGGGCTTAGCCACCCTACGATTCCTGACTGGTCCCGTATTAGGATCAATACAACCCTTCAGACCCTTGAGCCATGCCTCAAACTGCAACCGACTACAAACATATTGTCCTCGATGAAAACCAAGTGCCCTTAATCGAAGGCAGCACACTAAAAGTGATTGAAATTGTCATGGCCCAAAGAGCTTATGGCTGGACTCCTGAAGGGGACCTCGATTAATCAGTTTTCTTTAGCTAATGGCGTCTCATTTGAGACCGTCAAGGTGACTCAAAGAGAGTCCGAGACATTCCACCGAAAAAAGCTTCCCATTTTGACAAAAAAATAGGGTTGGAAGACCACGTTTAAGTCGATTTCCCGGCTTTAGGTCCGATTATCTTGCCAGTTCAGCCGATGCAGCACGTTGGGTTTCGAGACACACAAACCGCTTCAGGTTATACACCAGATTTTTCAGACCTAGCTGGGTCTGGGCACGGGCTAACCCGATGCTGCGCACCACCTTGCCACCCATGCTGGTGACGACATCTCCGAAGATGTGCTCCACTCTGGCACGGGTTTTGGAGCGCTCTCGATTCGCGGTTTTCTGGGCCTCGCTTAAGGGGCGATTGCGATAGGCCCGTTCATTTATATGCGGCTCAAACCCTATCAATTTCAGCACCTCGACAATCAGCACGGAGAGATACGCACTATCGGCCCAAAGTCCATCGCCGCTATTATCCGCATCGAGCAACTCGCCCAAGACCTGCGAGTCATGGACCGACGCATCGGTGACGCTGTAACGGCGAATGAGCTTAAAGCCGGCATCACTATTGATGTGGTTTTTGTAGCCGTAGTGGGACGTTCCATTTTTCTTCGTCCATCGGGCGTCAACATCTTTTTGCGCGAGCTGATGAGGGGTCTCTTGCCACTCAACGGGAACCTCACCCTGCTTGAGGGTTTGGTTCTCCTCACGGGTGTTGCGTTGTTTGGGAACTGGAATCAAGGTCGCATCCACAATTTGCCCATCCTTGGCGGCATAGCCTGCCCCTTGCAGATAGGCTCCAAACTGCTCGAACAACGCCTCCACCAAGCCGTGCTGCTGCAACTGTTCTCGGAAGAGCCACACCGTCGTTGCATCCGGGACTCTATCCTCAAGCCCCAAACCGAGAAATTGCATGAAGGACAGTCGGTCGTTGACCTGATATTCCAGTTCGTCATCGCTGATGTTGTATAGCTTTTGCAGCACCAGCATCTTGAAGAGTAACAGGACATCGGTGGGGTTACGACCGGCCTGGCTTTTGCGCGGTTTCTCTCGAATCTGCATCAGAATCGGACGAAAGGTCTCCCACGGCACCAGTTGATTCAACCGATTCAGTACCGCCTTCTTTTGCTCCAGTTTTTGCTGGCGCTCTTCGATATCCCAGAATCCCTGCTGTCCCATGGCCTGCGTGCTTCAACAAAACCGACCTTATGATCTCATACTGAGATCGCTCTGGCTATTTTTCGAGGTGCCCTGAAGAGATTTACGTTAACCACCGCAATCTAACCATGAGTCAGATTTATGGAGCACTCTCCTACTACTGGGATCACAAAGCAGACCTAGATGCTGCCATTGAAGCCGACCTTCAGGAGGCGGAAGCAATGCGCTTAGAAGCTGGCGAGTCCCCCTTCGTTGCACGACTGAAAGCTCAGGGCTTGTTGCAATGAGCCTCAGCTTGTATATGGACGAGAATGTTCATGGTGCCATCACCACAGGATTACGGATAAGAGAAGTTGATGTTCTAACCGTGCAGGAAGACGGCAGGGCTATTTCATTCTAAAAATGGCCTTGAGGGTATCTAGACCAAACTTGCAGAGTCGTTCAGCCTGAGCCATATTGGCGAACTCGTTGGAGCGATAGAGGTTGAGCGCGAAGTTTCGAGCGACGGCGAAGATTTGCGGCAACTGGTGCATACGAATGCGCGAAGCATCTTCTCCCTGGGTCACATCCCGGATATGATGTACCTTATTTTCAACGCCCCAATAGCCCCGAATGCGCCGAGCCAAGGATTCCGCTGATTCTAAAAACGAGGCGACATAGTAGCGGGTCTCAGTTTCTAAGTGAGGCTGCCCGCCCTTCTTGAAGTGTCGCTCACTCTCCACTCGAATGAGCGTCTTCAGCCCTGGCCAGGGCTTGATGTTATCGAGGGTGGTGCATAGGCTAACGACCCGCTTCTCCAGTCGCCCATGCCCTTTACTGACCTCGGTGTAGCTGTCCTCAGCGATAAAGTTGGCCTGAACGCTTTTGTGCAAGTTACCCTGATTGCCTTTGAGGGCACCCAAGTAATGATTGTCGGTGTCAAGGATGAGCTGACAGTTTTTTTGGGTGCTAATCGCATCAAAGGCTATCACCACCCCCTTCAGCGCCAGTTGCTTAATGAACTCGGGCAGGGCTTTGATTTCGTTGGTCTTGTGCTCTACCTGATAGGGCTCCAGAATCAACCCCCGCTCCACCAGATAAGCACTGACCAATAGAATGGCGGGATGAGGGGGAGAGTCAGGATTGTCAGTCTCCAGTTGATACGACCCGCGTAAGACTTTGCCATCCACCGCTAAGGTTTCACCGGCTAACGGTTCAATGCCAAAGAACCGAGCCAAGGCCGCCGAATACTGTCCATAGTCTAGCTTTAGCAGCACCCGGCGAATCGTGCTGTAGGAGGGAAGACGGCCCTTGGGCGGGTTGAAGAGGTCAATCAACTCGCTGCGGTAGCTTTTGAGCCAGTCGCCAATGGCCAGAAATCCACGATTACCGGCCGTCACCGCCAGGGTGAAGAGCGCCAGGCATAAGGCCATCTGATGTCGTTTGCCAGAGGCCTGACGGACATCTGGCAGGGCAACGAAGGCTTCGAGGATCTCGATGCGCTCTACAGCAGGCTCATGCCTCGAGTCGAGGGTAGTAGGGGTAGGGGGCAGACGCATAGACGCTAGGACCATTGGGATTAGCCTGAAACTCTAGCATCTTTAGGTCCCCTTGAGAATGAAATGGCCCTGGGAAGACGGACGTTCTGGCATGGCGGATGATCTCGTTATACAGCGAGCAACTGAGCTAGAGCGTATTGTCTTCTCTCAGGACCGAGATTTTTTAGTCGAAGCAAAACGGTGTCAAGAAGATGGCATCCGTTTCTCTGGAGTTGTCTATGGTCATCAACTTATGGTTCAGATCGGAGAATGTATCCGAGATTTAGAGTTAATCGCAACGTTAGGAGAACCGCAGGAATTTGAAAATAGAGTTCAATTTCTGCCGTTTTAGTGTTAACTAGCTGAAGGAATTAATTCGGCATAGATGACGGCTCAAAGTAGGTAGGGTGGGCAAAATCAGGATAGATAACCCTCGCTGGTGCCTGTAAGCTTTGTTTGCCCACCAATTTTTTCAGCGGTGGGCATTGTAGTTTGAGTGTGGGTTAGCAAAGATTTCGGACAAGATAATGCCCACCCTACGAGCTCTTCCCCTGACTGCCTGACACATCTTTTACTCTAGTCGGCAGGATAGAGAGCGGATGCGAGAGAACCAGATTTGGTCGTAATAGTCGTGCTCCGCTTTTTTGGAGGCAAAACAAGGCTCTGGGTCACGGACTAACAGCGCTATCGGCTCTAGAAGCTGTCGTCCTTTGTGAACGACTCCCTTAAGCCAGCGCAATCCAATCTTGAGGTAGCTGAGTCCGCGCCGCCAATGAGGGTCTACCTGCTGCCTAAGGCCTTCAATCTGAACCGCCATGCCAGTGGTTGTTCCATAAAGCAGTGCAATAGCGGCCACTAGATAAAGTCGCTCAAGGGCTACCGCTGAGCGGATTCGGGAGTCTTCAATCTCGAAAGCTCCTGATTTGCTATCCAAAAACAGCTCCTCTACTCTGAAACGCAACGCGTAGCGCCAGAGCGTCTGCAAGGTAGGCGGTTCATCGGTGATGACGGCCCAAGGCTCTTTGACGCCTTTAAGCGTCGCCAGCACGATGTTGCACTGGTGGGAGCCATCCTGCCACAGCCTGACATTTCGATAGAAAATCGCCTCGCCTTTTGGCGGCCACAGATATCTCACTTCAGTCGGATAACGCCTTGGCCCGTGCAGCAGGACATCGCAGGGCACTCGCAAGCAGTAGTGCCAACTGCTCGCTTGCAACCAACTCATCAAGTCGTGGTTGGCAAAGCCTCGGTCGGCCAGCAGCATTAGGTTCGGGTACTGCCTCAAAAGCCACCGGGCACGGCGCAGCAAAGGGCGGTATTCTTCAAAAGCCACCGTTGCACTGCCATGCTCAAGCACTCGCCACAGTAGCGGGACTGCTCGTCCGCAGCACACCACTGACAGGTGAATCATGCAGTATTGGTTCCACAGCACCGTTGTATCGAGTGCCAGATACAGCCGCTTGCCCTCCCACTGCCTCAGCGTCAGCAGCACCAGCGGTAGGTAGAGCTGATTTATCTCAACGAGCCGGTTGCCGAAAAATCGATGCCACCGCCGCTCGAAGCTTTGCGCTTTGTTGGCACGGCTTATCACGTAGGACTCCCAAGCAGGTGGGCTCAGCTCACCACTACAAATCAGGGCGGTGACCATCCAAGATAGGGCTTTGATATGGCGCAAGTCCCGGTAGTGGCTGTATTGACGCAGATAGTGCAGCAGTTGATCATAGAGCTGGGTAGAGCTTGGCAT

Protein sequences of DBSCAN-SWA_2

>NZ_CP021983|782611:838302|816785_817835_-|WP_080808767.1|DBSCAN-SWA
MYHRAYGIIETLAPLHVGASAGEETGNLNLIFRDQFTQTGIIPGSSIRGRFRADMRLRRQQHLEASLKAAGVDLPAATARKVSSPEDPKKRLPRLEWLEQEAEKQSISVPELVNENHWYGHHAVTGQEDGGTTEALVKFEYASLVWIPVFCPGQPVVWVSCPRLLRRYKQITGKPEPVLRPKAAADGQPKQYPVKLREHRDRLFFNLGFLDNLAETPDLSNWVPKDSQIQPDNLVVVDDQDISIIHDMALYRQTRTKLEDDVKKVENFFGFEALPEDSILIFPIAVKDSVPHYDRASDASADGSARWKPFKNRTLRELYFGGLESIGCGHCEVTLAGDYFGDTPDDADA
>NZ_CP021983|782611:838302|799828_800029_+|WP_080808810.1|DBSCAN-SWA
MTRLSSHQADQFADDATIWQSLKCAIANSSGFQRWQGEQSETDLAKTPLEQLVRRYLRETLETLAY
>NZ_CP021983|782611:838302|825595_825871_+|WP_080808744.1|DBSCAN-SWA
MLVLITYDIPDNKRRTKLATFLEGYGRRVQKSVFECFLTQAEMQELHRRIQRRVNPDEDNVRFYWLTPQSVAKSLAIGSDPPTPPPNVYII
>NZ_CP021983|782611:838302|811964_813031_-|WP_088429129.1|transposase|DBSCAN-SWA
MSPEDQAALAQHSREIAKILHRNSPPEAVDTLEGIETTVRQQMLEHVSPEVGNFFVEACTQTQRGRPRQLKSVLGTLPIREQQAQRLGLEPHGRLSPLFEKCALRVAACQSYGKGETDVSVLTGMSLSHSTLQRLVQRQRETPPEAKQTVTEISVDGGKVRLRHPEKGEPSYWKEYKSARVENLYYGAAFQANDWLQDWLNSQPLANPIICLGDGHRGVWAVFRPIATVETRLEILDWYHLVENLYGVGGSLKRLKQAKALLWEGRVDETQALFTDCALEQARRFCDYLERHRHRIVNYGYFQAEQICSIGSGAVESAIKQIDHRMKLPGAQWVPDNVQQALQVRCAYLNRAYDC
>NZ_CP021983|782611:838302|821386_822100_-|WP_080808759.1|DBSCAN-SWA
MVLLHAVIAQATSDPATPTDLIKLFRESHAQLTTSFNLFVGAISTIFVVVGILLAFVGVRTRQEVQQTIQEVKLSVAEQVRSEVDRQIATKVDEEIGYIKKMVGREAAIGRTQVDYVFVAGEPERYPTEYDLLDARGFQMAPFLYDPERAWPESHVFVLDLMTPSLSPERKEALVKEAAAKLTQRRRPTVLVIYVKGIIEAVNTFPEDFNYIMSNMRGTLISAVVDAAQITQALRSQ
>NZ_CP021983|782611:838302|793336_794869_+|WP_088429116.1|DBSCAN-SWA
MSLVNLPNLQELIDHISRERNLPKHAVENALREALLKGYERYRRTQRMDGNVQFEEDYFDNFDIELDTDEYGEQGFRVLASKAIVEEVQSADHEIALVEVQEVAPEAQLGDTVVLDVTPEQREFGRMAAIQTKQVLAQKLRDQQRKMIQEEFQDLEGTILNARVLRFERQSVIMAVSSSLGQPEVEAELLKRDQLPNDNYRANATFRVALKKVSEGSHRGPQLLVSRADASLVVELFSNEVPEIEDEIVRIVAVAREANPPSRSVGPRTKIAVDTVERDVDPVGACIGARGSRIQVVVNELRGEKIDVIRWSPDPATYIANALSPARVDEVRLMNPEERQAHVLVPEDQLSLAIGKEGQNVRLAARLTGWKIDIKDAAKYDYAAEDEKQAEIQAQREAQQQVALAATAATATDLEANLEDENGAAEEALAPVTGPSLADAAMATEERATAREAGTPEASTPAESASEAVSDNAASAEDSLEENTLAEDLEEDTVDETPVESDEAYPREEE
>NZ_CP021983|782611:838302|788132_789026_+|WP_080808834.1|DBSCAN-SWA
MQVIGIDLGGTAIKAGRFNQAGDCLQSLTMPTAAPPHPDQVLAQMAAAIASLDPHHQVHAIGVGTPGPADAAGRVARIAINLAGWIEVPVADYLEAKGGRPTVVANDANCACLGEAWLGAGRPFRDIVMLTLGTGVGGAVMLNGQLFLGRHGAAAEPGLVTLNPEGPACNSGNRGSLEQYCSVQAVRRQTGQEPSHLAARARAGDADAIAFWQQYGRWLGAGLASSVYLLTPEAIILGGGISASADLFLPSTLTELQQRVMATSYDNLQICIAQLGSQAGRVGAAKLALQQLGLGRD
>NZ_CP021983|782611:838302|807837_808392_-|WP_080808787.1|DBSCAN-SWA
MTISTSSLTLEAFLKLPETKPASEFIDGKVIQKPMPQGEHSLLQGTLCETINQQAKAAKVAMAFPELRCTVAGRSIVPDVAVFRWSRIPRQPSGRIANRFTIHPDWSIEILSPEQSQTRVLGNLLHCAQQGTELGWLLDPEEETVLVVWSDQRVQLLRGDVPLPVLTDINLSLTADQLFGWLMV
>NZ_CP021983|782611:838302|804870_805626_-|WP_088429126.1|DBSCAN-SWA
MTPSAAPQTLSNRQVIWVLAGSVGLALAVGSLVRLMTASPEQADVSTPKVVTETSPAPPLFTSPLASTTSLLTLADPGLLQPSDKAARLAQVTAGRTDPFAPLTRPSLTGPDAATATPVATAATTTPVAVATPPQSLPTVSVTAPPASLPPLPSREVAPETPAVAAASSPARNPVDALELSGVVQVGDRIHLIVKEPNAKTSRYVSVGDSLAGGRVRVHRIEMSEEPVVILAYNGQHYTRTIGSMVVAGML
>NZ_CP021983|782611:838302|810790_811069_+|WP_080808779.1|DBSCAN-SWA
MELLEVDDRIREIMYDGTITQLQHHLSKVGFLSFRGAAIEKLLTGATTSEEVLRVLPRSSLTRKTAADTEVLQLVPSGSDAFAVASEKLTYS
>NZ_CP021983|782611:838302|790290_791754_+|WP_088429115.1|DBSCAN-SWA
MAALARSHKIPRRRRTKWLWFERLMALIALVNLALVLFDLSYIRFRDFYLKFVPELTEWYGATYKGIQPERSTVTYLETVDRLEEQVAQTGLQSRQATILLNQLQQQSIELIDENPFQVANKSGTLERIKNMMRDRIGTDSAKVAFRTFWSQDHLSQNPWSEEIDFFNDDIKPLMQTNYFRRIGIDGLPLDWFWQIDGWFILVFGLELAARSFYLCRHYKNVTWLDALLWRWYDLLMVLPFSAVRMPVLGLSRTITVAIRLDQSQLIDLQPLRNRINRFFISQVAIELTEVVILRIIDQCQNLIRAGDVTRWLVDAGTGRRYIDINGIDELQVMSQRFITILVEQVLPQIKPEIDAVLNHSLNQVLGQAPAYGGLRRLPGIGTLPDQLAQRLAAEISTNAYDALKQTLEDDQGAVLIRSLVAKLTDRLRHEVQQDDTLDEFESLTVALLEEVKLNYVRRLAAEDIEQLMEERYRLYNVTQEGRASSN
>NZ_CP021983|782611:838302|816344_816767_-|WP_080808770.1|DBSCAN-SWA
MGWQAYGLDREAQWLVLQALDIDNDKDIKGDACLRESYKMRESVAYGLERFWGEHMRHQGKQEKKSRYWKATWDILANILGPADVTLPNDSDPKAMAQKLWGEIPVDSSGKMLTLEDQRLALAVLTQLCDCLVWWTQRYK
>NZ_CP021983|782611:838302|835427_836579_-|WP_088429135.1|transposase|DBSCAN-SWA
MRLPPTPTTLDSRHEPAVERIEILEAFVALPDVRQASGKRHQMALCLALFTLAVTAGNRGFLAIGDWLKSYRSELIDLFNPPKGRLPSYSTIRRVLLKLDYGQYSAALARFFGIEPLAGETLAVDGKVLRGSYQLETDNPDSPPHPAILLVSAYLVERGLILEPYQVEHKTNEIKALPEFIKQLALKGVVIAFDAISTQKNCQLILDTDNHYLGALKGNQGNLHKSVQANFIAEDSYTEVSKGHGRLEKRVVSLCTTLDNIKPWPGLKTLIRVESERHFKKGGQPHLETETRYYVASFLESAESLARRIRGYWGVENKVHHIRDVTQGEDASRIRMHQLPQIFAVARNFALNLYRSNEFANMAQAERLCKFGLDTLKAIFRMK
>NZ_CP021983|782611:838302|802691_803111_+|WP_080808798.1|DBSCAN-SWA
MAPLPQKRPRQLSLGPLEQEIMAIIWQANLTTATAIHGYILRDPDRELAYASVMTVLQRLGKKGWVTCDRSQRPYRWYPVVSSQEAAVWKAHQQLADFLAVGNPDVVAAFADSLDTASVEQLDAIARRIQAIRQQRQAP
>NZ_CP021983|782611:838302|784143_784581_+|WP_080808842.1|DBSCAN-SWA
MAHDVTQWLAEIRTLQQQLAQVRQERDDAYASAATWRRLYETEARQRRQDTQALRSQLQSLQETLTQLNGQGTDFLEHAVDLSQQQISDINTIDELRSHLTAVLQRCQQLRQALECERHQHGQTRQALTTALGDTFDRVKGWSSS
>NZ_CP021983|782611:838302|834015_835062_-|WP_080806623.1|transposase|DBSCAN-SWA
MGQQGFWDIEERQQKLEQKKAVLNRLNQLVPWETFRPILMQIREKPRKSQAGRNPTDVLLLFKMLVLQKLYNISDDELEYQVNDRLSFMQFLGLGLEDRVPDATTVWLFREQLQQHGLVEALFEQFGAYLQGAGYAAKDGQIVDATLIPVPKQRNTREENQTLKQGEVPVEWQETPHQLAQKDVDARWTKKNGTSHYGYKNHINSDAGFKLIRRYSVTDASVHDSQVLGELLDADNSGDGLWADSAYLSVLIVEVLKLIGFEPHINERAYRNRPLSEAQKTANRERSKTRARVEHIFGDVVTSMGGKVVRSIGLARAQTQLGLKNLVYNLKRFVCLETQRAASAELAR
>NZ_CP021983|782611:838302|817964_819155_-|WP_080808766.1|DBSCAN-SWA
MTTDSPSLPPFQYLITIQPLGLLYGSTGRFLSPENLVGRSGSQFPPSTAVLSGLIAAHYAQHAESKQALDDILKPLCLAGPFWQWTHTADRENIYVPTPMNCLAKLEPQHDATDVSEGSLVNRLEWDGQSWQPISDKALGKPEGGTWVAINDWKKLNEWQPDYQEPTVYGDPWRYTPHLHPYLMENERRVDADRERGSLFLENGVQMHPETCLVYLSNLSVENGWYRFGGEGHMVELTCHPISAGSELHKLLSHPLGKSFALITPAVWGSNRLSYRSPRLLKKGDKSRHQLAEINRDLAKLWDVATLITERPTTFRYRLGNRKNQQGEDVHQPNQPKVLSRGRYAVPAGSVYVLQDTFPDHHATWQDWPLDWFPREGPSLKRWGCGLALPVSGALP
>NZ_CP021983|782611:838302|795490_798505_+|WP_088429118.1|DBSCAN-SWA
MNNGKIRIYELSRELDLENKDILAICDRLNIAVKSHSSTITGEDAAQIRSAAKSARAGKAKPRQPEKAHNGARPPVRKQQILEIRRHRTAPKPPNAPEPPQSPEEPAAIDNDEVSQGEVDALMTPPSRPEAPTRPSSTQLKPPVSRPQSPGQAEAESPQPPKPKTASPPEPEEQPAEPSEDKATAPAAKAPSKPKPELIGPPPKPTRPKPKVTNRRAQADTSEPAAKSARQPTIPIREVDDDDDDGPKLKPKPKLRRPKPSEPQQDEQPVTPEQDDTEDSRDARDDSAREPLLKRPSPSRSQRRKTREEPVDEEQEMRPKADKKSKRRQAIIEDDDELEEVIEGGSGGQSDASSNLSVSLARPPKQKKASASKPSAPATRSYKPPSRDRSGSSRQQRRERQEQATQQERPEILTLTSELTVHELAAKIVVPETDIIKSLFFKGIAANINQTLDVPTAKMVAEEFDILVETAEAESEAKKITEMLDDSDLESLVRRPPVVTIMGHVDHGKTTLLDSIRKTKVAQGEAGGITQHIGAYHVDVDHEDDSQQIVFLDTPGHEAFTAMRARGARVTDIAILVVAADDGVRPQTIEAISHAKAAGVPIVVAINKIDKETAQPDRVKQELMEHGLVPEEWGGDAIMVPVSAIAGENLDNLLEMLLLVAEIEDLQANPDRLAKGTVIEANLDKARGPVATLLVQNGTLKVGDAVVAGSVFGKVRAMIDDRGQRVTSASPSFAVEVLGLNDVPAAGDEFAVYGDEKEARAVADSRATEQRQSRLQQAMASRRVTLSSLSAQAQEGDLKELNLLLKADVQGSLEAILAALQQLPQNEVQVRVLLAAPGEISETDVDLAAASGAVIIGFNTTLAPGARQAADRLGVDVRDYDIIYKLLEDIQGAMEGLLEPELVEESLGQVEVRAVFPVRKGSVAGSYVQSGKVTRNCHLRVLRQGEVVYTGKLDSLKRMKDDVKEVAAGFECGIGIDGFNDWKEGDIIEAFRLVTKRRTLAMAR
>NZ_CP021983|782611:838302|794948_795233_+|WP_080808818.1|DBSCAN-SWA
MKPNLRRCISCRKVAPKSALWRIVRVFPSRTVQLDEGMGRSAYLCPQVDCLRTAQKKNRLGRALKASVPPSIYEELWQRLESSSVKGSERSSPD
>NZ_CP021983|782611:838302|800225_801110_+|WP_088429120.1|DBSCAN-SWA
MVYRLPYWARGGVLLAALWLVGCGAISTPESTSNEAVSEAMTAENSAAPARQDQTAEVAADTSALPERQPQLVKQANMSLRLADVEAGIDAIYDLAVQQQGDILNLRDQQPDTGQPRQVSLRLRIPQSALEATLDALRQLGEVQQQQVTVTDVSNQLVDLQARLRNLRKSEETLLTLMERSGSVADVLQVAQELSNVRETIERLEAQRQQLNTQVTYATVQVQLEATVTPVPTNPPLAETLTNTWQQATHSVSDLSTGVLRLSLWLIAYSPYWALVLAAAWGYRRWQRQAQSSS
>NZ_CP021983|782611:838302|801702_802617_+|WP_080808801.1|DBSCAN-SWA
MTSSITQNSLYQPLHPFLVADHTVDFSGPIPVDTALTPSPAITANSNYFDHPDWALNYFNACHRTDGFKERWQAATGTWDDKIVVDVGCGPGNVFATVGGQPRLLIGVDVALGSLALAQEIGYVPLLADAHQMPLRSHMADLVLLNATLHHCENMERVLIEAARLVKPGGKLVIDHDPQLQAWNYRGLGMAMYRIRHHLYARCLKDLDMDPHERTYALATEIHHHPGHGVTAEFFRGSLGQLGFQVNLYPHNQTLGAETLQGQRGSFPHWRYPLGQILSGINPWSDEAALSLLCVAVRAVADYS
>NZ_CP021983|782611:838302|814400_816113_-|WP_080808773.1|DBSCAN-SWA
MSTLTDAANKVPLMFRAQVEGRCQVQRLIPKALEQDAERWADEWVDKAYPDAPNFGKDVQTRPYALSWRFITNSGQDDGVIRPVIGARGWPFYPGSSMKGVFRQAAHQLERAGELKLGTCDRYCGEKLENNDFRPGILRFHGGYPTDTRWTQNLVDIVHPQQQWQVKSNDKEGGAFIQISLYKPELIVGISSTTPLDDLEWEQIWHIWETALSLGLGCRVSAGYGQPQQRSGDILYRTRLKGQGQAAKLVDGTGEFRPNVFRAAIRGHALRIFGGLTNADQAEGLVQDLFGGIRGGATVGLLSMAFLDTQLELDDFGQGSYSQPTYTVEGELLWRLTRDLPQPQRQALTKLIEALTRFAMVFGGFGKSWRRADHRLVYPDYYDQGYKPLIGCHWEWLGKRSQVRDVRVRKLEKVGDFIAEVRQAAKEWMQLQTRTPQLDTHANWREAWHPDKVQVWGRETDGLEDCEAVRWLHGPYREAIPSVGIPEGSIYRSSITGQMGNVGRLWHRMYPKVRLVKDPENPKKPMPLVTRQYFELVTVFPDDSVESEQLLGFLNGQQTLFKKLWPMPRH
>NZ_CP021983|782611:838302|808397_808982_-|WP_080808785.1|DBSCAN-SWA
MTPSTATTQISFEDYVAYDDGTAARYELVDGALVAMTPPTFRHMLIAKFIEQCLDTEIRRLGFRWLCFREAGIRTGVRKSRLTDVYVLTPEQVSNFLDESAICQTAPLLTVEVVSPESVSRDYRYKRTEYAALGVPEYWIVDPLQSTVTVLQLDEGMYEETVFVGHQPLVSPTFPELDLTVETLLAAGELAEEE
>NZ_CP021983|782611:838302|822428_823046_+|WP_088429131.1|DBSCAN-SWA
MVTIPLPDAQLMSFDEFIAWKPDNQPYELHHGTPIEMQPTGDHEEIIAFLNSVLVLEVHRLQQPLMLPKQALVKLPDEDTAYLPDVLLLNREALPQEPLWKRASTVTQGISVPLVIEVVSTNWRDDYGKKLVDYESLGIAEYWIVDHLGLGGRRYIGYPKQPTLSVYRLVDDEYQVRQFRGQEPIQSGLFPDLALTATAIFRAGP
>NZ_CP021983|782611:838302|792801_793272_+|WP_080808823.1|DBSCAN-SWA
MTHPLIPQILDLAAPVAERLGLEIVGAVFQTNQAPPVLRIDVRNPSQHDTGLDDCERMSQGIEAVLDATDIIPDAYVLEISSPGISSQLTSDRDFIVFKGFMVEVHLSTPHRGKHQWVGQLIRRDDTTLYLNQKGKSISLPWKAVESVQLSNQSVD
>NZ_CP021983|782611:838302|786512_788027_-|WP_080809199.1|DBSCAN-SWA
MSSDGYLERILLARVYDVAQESPLEVAPNLSTRLQNQVLLKREDVQSVFSFKLRGAYNKMAHLPPESLAKGVIASSAGNHAQGVALGARHLGSRAIIVMPTTTPQVKIDAVKARGGDVVLHGETYDDAYSHARQLEREKGLTFIHPFDDPDVIAGQGTIAMEILRQYQQPIHAIFVAIGGGGLIAGIAAYVKRLRPEIQIIGVEPTDADAMYQSLQAGQRVRLEQVGLFADGVAVRQVGAETFRLCQRYVDRIIRVDTDDTCAAIKDVFEDTRSILEPAGALAVAGAKAYAEQQGIQGQTLVAVACGANMNFDRLRFVAERAELGERREAIFAVTIPERPGSLRQFCECIGKRNLTEFNYRIAHQEEAHIFVGLQIRDRVDAAEIAAKFESQGFTTLDLTDNELAKMHLRHMVGGKSPLAQDELLYRFEFPERPGALMKFVTAMSPNWNISLFHYRNNGSDYGRIVAGIQVPPQDMDDWQAFLDTLGYPYWGENQNPAYHLFLG
>NZ_CP021983|782611:838302|804292_804763_-|WP_088429124.1|DBSCAN-SWA
MRLSLTNQYLCPVCRHGHIHALVLMESFSCDFCRHMFAANLSEQTIHMVDGTQPTGWRWNGRTWKSLRQGDLDMTLMVWIVGILLIIAPVGLISVSAYMFPPLDEALAWPIAWAIITLLTHMTLVVWLLAEHYQVSTYIAIKVRLRQLIERFQAIT
>NZ_CP021983|782611:838302|824591_825596_+|WP_088429133.1|DBSCAN-SWA
MCDLYVVKQGTCLRKEHGRFILNPPEDDGLEIPIREIERILLFGNIQLSTAVIGTCLQQQIPVVFLSRTGIYKGHLWSAELRDLEAERNQFLNYTDRTFHLETARAIIRGKLVNSRQLLLRLNRKRHLETVANAISGIQRDINASETAGSVDQLRGYEGITAARYFPALGQLLITPDFTFEERNRRPPRDPVNSLLSFGYTLLSNNVMSLILAEGLNPYLGNLHRSDKKLPELVLDLMEEFRSPVVDTLVVTLINRRTLHPDDFTWPTETGGVYIADAARRRFIHAFEANMNQSVKHPDVQEPVTYRRAIHYQVKRYKRALLEVIPYQPFVRAA
>NZ_CP021983|782611:838302|782611_784078_+|WP_088429113.1|protease|DBSCAN-SWA
MLFWLLLLGIFTYVVVKRSVANVTRTPTWLLWLVMMLPAFSLVIWASVQGSEEPFPTVLLISLFVLCPLLYWWLIQWGRPQPAAQVKARPSERTTLPSSEESKSTLRPMNRDEEATLKHCFPWTVYYLQNIEYRPQAMICRGQLRATPTVAYETVRENVHSRFGDRFLLVFQEGFNGKPFFALVPNPRTQTQQMSTQPPLTRPGLALGLFLTTVFTTTGVGAIIAGVSEETLQADPASILRGLPYALALMAILGIHELGHYLMARRYQIQTTLPYFIPVPFFLGTFGAFIQMRSPVPNRRALFDVGIAGPMAGLVITLPVLLLGLRLSTVVPLAEEASLLNFEALDPSASVMVALLSKLALGSRLTLEHAIHLHPMAVAGCLGLVVTALNLMPVGQLDGGHIVHAMYGQRTGAIIGQVSRLLVLALAVVHPELLIWAILLFFIPAVDEPALNDVSELDNQRDLWGLMSLVVLVMIVLPAPSPLLSLLF
>NZ_CP021983|782611:838302|813049_814282_-|WP_080807200.1|DBSCAN-SWA
MSTRKRFYVFNIYGDSKVGKTFLLKEFRNIALENNSFTSLIQKDLNDIPSIMQKIYEDLKESEVSNPIFEEHYSTYIRLKSKLKNTTDIPEAYIDLIGSNLTNINDFRISPEKEKIKNRLDINRIGQDREIQEGFQKAILDLKKFIKSEIVNSDDRKLLENPIDVLTFELLRALRSAAIDQPIVLFFDDYHINKNILDPWLIGLVETVGSSRGLPGNSIVVISGREKLDRETWLLFDSFISDVKLNRFRANDISVILDHQGIKDEIIKRFISKLTGGVPLHLKDLVKDLRNITKNNIHLDETIVLECYLNNRKTLINRKIFLDLAVPRIINESIYNLLVGTRLKQTSFELFTTIPFLIHRSDGWLYDSLIREKTISYRRSTLNPELQETHRRLGSISFLREPSICAEMKG
>NZ_CP021983|782611:838302|823943_824363_+|WP_080808756.1|DBSCAN-SWA
MARRKRNSATLEQVERRLESIRSIATDLDLGGGLSVQNFAIIVGDLAAKLAAYNTALSNIDKMADDVRVAEQAAKTMAENMLLGIGSHYGKTSQEYGMAGGSRRRGYRHPQVADPVPDPVTIPVVEPSQNGASAEPVLV
>NZ_CP021983|782611:838302|784577_785642_-|WP_088431508.1|DBSCAN-SWA
MGTRPWPGLIETYRPFLPVTDATPIVSLCEGNTPLIRVPAIAERVGRSVQVFVKYDGLNPTGSFKDRGMTLAISKAKEMGAEAVICASTGNTSAAAAAYARRGGLRAFVIIPDGYVAMGKLAQALLYGAEVLAIQGNFDQALTMVRQLAEHYPVTLVNSINPFRLEGQKTAAFEVVDVLGDAPDWLCIPVGNAGNITAYWMGFCEYHQQERCQRLPRMMGFQAAGAAPMVLNHTVTHPETVATAIRIGNPANRDRARAVQEASQGEFSAVTDEEILAAYRLLAAEEGIFCEPASAASVAGLLKVKDRVPAGATVVCVLTGNGLKDPDTAIKHSQNQVKGGLPADLETLAGVMGF
>NZ_CP021983|782611:838302|811216_811912_-|WP_080808776.1|DBSCAN-SWA
MLSEIRQDLDCLEKNDSKYSRYENYLKKHQIEFYYHEICATGTDRLLDAINEFWMNFIESTKYAADIASSILQAGEDSDEEEIYNCGSQLLTCIGLYEEKDFSELINIINEIIERWGFLISDDVCSLLTCLRDFFQNELESDEYLEEDQVKTYDEIKQRNELFDLIQNLPQVQFEQLLFIVKPPSNVIPKSSAAQGIRTYALLEWSESSSECGLQRIDEALKTLSTSLIRK
>NZ_CP021983|782611:838302|837129_838302_-|WP_080809504.1|transposase|DBSCAN-SWA
MPSSTQLYDQLLHYLRQYSHYRDLRHIKALSWMVTALICSGELSPPAWESYVISRANKAQSFERRWHRFFGNRLVEINQLYLPLVLLTLRQWEGKRLYLALDTTVLWNQYCMIHLSVVCCGRAVPLLWRVLEHGSATVAFEEYRPLLRRARWLLRQYPNLMLLADRGFANHDLMSWLQASSWHYCLRVPCDVLLHGPRRYPTEVRYLWPPKGEAIFYRNVRLWQDGSHQCNIVLATLKGVKEPWAVITDEPPTLQTLWRYALRFRVEELFLDSKSGAFEIEDSRIRSAVALERLYLVAAIALLYGTTTGMAVQIEGLRQQVDPHWRRGLSYLKIGLRWLKGVVHKGRQLLEPIALLVRDPEPCFASKKAEHDYYDQIWFSRIRSLSCRLE
>NZ_CP021983|782611:838302|819175_821074_-|WP_080808763.1|DBSCAN-SWA
MSKPVYTAITFAPIQGFIENSRKLRDLYGSSYLLSFLSWAICSAQPECSVISPALPNVRQGMPNLILVRGNVPPEETETAFFSAWQCVVDTCRQWIECKISDAYYWERSWGLWAKYAWEFFIATGCSIPAARTAVLEKKRSRNWTGVNWTGESSTLSGADGIAWPKLGYLSPRDINYQQQKTEIEAFYATLSRTLGQAFIEAVGLTPADPETKAIEYGAAFVDPDEELSIPELVKRLVTHKALSERIQTNYQSQVRDYDLDRDQLQSITAIAHELDPQRFTDLNRLKRKYKKANQALEPEYWTGWFMGDGDNAGNYLAHHCHSDEDYTDFSCQMRQWGQRLYQNEWPQADGNGQTEPILPGNGRMIYAGGDDFLGVLYRERAEIQPHECLHWFSTFKSHVWENPDLTRPSAAVSNAPPTSDNDSKPITVSVGFVWAAPKVPQRDVLQHCREAEKSAKRHGKDRIAFRILFNGGNHLEWVCPWWLLEGDFSGSQDLDSLDTHDLSGLMPTCNDPGWTHIYNDIAVLEARHAFHGAQIDVALGLIEVYFGRPYRQLLGHPSNWWNRDDPNTGKRLFSGILGDPQRYMPEFDSSNDAWQRLNTHRFVLRDFNTWVINLAKVGFHLNRSDMAQLAA
>NZ_CP021983|782611:838302|798504_799599_+|WP_080808813.1|tail|DBSCAN-SWA
MQSFRLDPYLWIHLAGLAAVPLWFDVCLLGLAAGDPVLPVWLELGVLAVVGVLPVLWMQWQRPFCIFSLVALALKPDQMSPNQRRLLHLFQDPIGRGVSLLVPLPLLWGLWQLYRLAPLAANSTPFSNRGVGVLVAAIAFLLVNLFTQVPVRVLRVLLAPATALDGVDPYAPEAIPQDFTLIGLRVNQILPPLEIPSAEAPPESPSQPAVTDQEEIAPAPLAKEDKEDGDETDDTIVSQTEPAPEEEPAAAEMAADVSTDAGLAAWPVDDSVEALDYEGQAPQPAESESVDSPEGDGQDGPESSSEESSAIESHVSSDAPQPDDSNGYHLQETDVQPPKGHSEHEHESSSQSPDEPGDAESRSE
>NZ_CP021983|782611:838302|789065_789992_-|WP_088431510.1|DBSCAN-SWA
MSDRNPIDSSGVGQHWTWRGQPVYYVQAGPPPGDRPPLLLVHGFGASTDHWRKNLADLQHQFQVWAIDLVGFGRSAKPPWQYSGDLWQAQLHDFITQVIGQPVVLVGNSLGGYASLCVAANHPEAAAGLVLLNSAGPFSDAQVSTAKSSIGGALAKALRSVMLQPLPSWLLFQYVRRRATIRKTLMKVYLDATAVTDDLVEAIYRPACDAGAARVFASVFKAPRGEPVDVLLTRLCPPLLTLWGEGDPWMDTRQRGARFRQYYPQLTEHYLPAGHCPHDERPELVNDLMRDWVLTRVCGQPISGPYPE
>NZ_CP021983|782611:838302|809407_810589_+|WP_080808782.1|DBSCAN-SWA
MKTIRSLRLSQRLPILLGVALTACAQITVTGLTQGEQANQTITVNALEIKRGRIDTLARVQTFQGQPAVDSINELAIQLSITEANNPPDFSETYYYLAISSPKEAILGGTTGDPNYVPNQIGKLTFLTLNQGDNRVEAAPQIGDAHAGASWLARVEADDRTIPWSITEGDNCFLLEAEEEDCFDMETLSRLLFETLADSIEQGMRNDIPAIQSIRHRLHFVPRVSHPAIGLNNRPAKGFGFIYFAQINVPGANFQVYIPINFLFIANVNQYILVVDPLELDTQDQKTIAQIYVKENIAGGIDLNLTEQIIRDQLIDQLQAAPLPVLIPGIDFSEALLTAMNGAAGNPSQLSDDFDILLSPSGENRDLATTILWEQLVPGNILPRNQVDLFFLE
>NZ_CP021983|782611:838302|791788_792583_-|WP_080808826.1|DBSCAN-SWA
MAKPAKHANAFDPIVVLIQGNVLFRHMEPSWLASYLSPDTLILEKLYSNRPVFTAFRPQTWLEHLYAIVAGGPVVVRSTPLDRIIALTYPGGCFGMRNLAFSHGPVLRAFPSLVEAYKTTDVIKLPVAAVQALYRDSDVFRQRYDLLFEMREKFQYHLLNCSTYPPQAVAALLRALIYQERSLGNQPSLDGTYSFDLPVDIIARACQLNHRTVEQVLKGMTQIGLLKAGKAADSNPDTVQVVDPEALKQIYGATRDKVSWWPLR
>NZ_CP021983|782611:838302|833018_833363_+|WP_088431512.1|DBSCAN-SWA
MVEVARDLRQQQTPSEEKLWQQLRRKQRGYRVRRQQPIGPFIVDFYISQARLVIEVDGAVHTQHIEKDKQRQDLLEELGLTVLRFSTTAVEQTLSEVLEQIDTYVQILTTQTNI
>NZ_CP021983|782611:838302|803110_803962_+|WP_080808795.1|DBSCAN-SWA
MHLSLLLLIGLLAVVMRLLWPRPQGSWPQRWWSTLQGFSLPPLLLLTMALAVLGMGGHGHMLGLPVSHGGCGLALLWWGIALGHLVWAGGQMVRSHQQTKHLPVLALADDHPVSILPVAIPYAAQTGIWQPKTLLSQGLLQELNQEELSAVLAHEAAHCHYQDPFWFFWLGWLRRWSGWLPRSEDFWQDLLLLRELRADQWASQRVDPLLLASVLVKLAAMQQSLAIPGAISLHEASLNRLEERVDALLNAAATDSVDSPASVFPYPGWSMALLPLLTILLHQ
>NZ_CP021983|782611:838302|786048_786306_+|WP_080808837.1|DBSCAN-SWA
MSMLSAPSRCEPPYALLEQSRRPPEASFPHAIAPTNWIADQTSPYSLAHQVELQHLQAEADALLRQLQAIQQARGTSPTSTLQQK
>NZ_CP021983|782611:838302|803996_804188_-|WP_088429122.1|DBSCAN-SWA
MKRAIRLNNFAVEPKVYGDDHQRFGFNRYAEQLNGRLAMIGFVSALLFEALTGQGVFGWLTRL

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_088429113.1|782611_784078_+|protease	site-2 protease family protein	NA	NA	NA	NA
WP_080808842.1|784143_784581_+	hypothetical protein	NA	NA	NA	NA
WP_088431508.1|784577_785642_-	threonine synthase	NA	NA	NA	NA
WP_080808837.1|786048_786306_+	hypothetical protein	NA	NA	NA	NA
WP_080809199.1|786512_788027_-	threonine ammonia-lyase, biosynthetic	NA	NA	NA	NA
WP_080808834.1|788132_789026_+	ROK family protein	NA	NA	NA	NA
WP_088431510.1|789065_789992_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_088429115.1|790290_791754_+	hypothetical protein	NA	NA	NA	NA
WP_080808826.1|791788_792583_-	cAMP-binding protein	NA	NA	NA	NA
WP_080808823.1|792801_793272_+	ribosome maturation factor RimP	NA	NA	NA	NA
WP_088429116.1|793336_794869_+	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_080808818.1|794948_795233_+	DUF448 domain-containing protein	NA	NA	NA	NA
WP_088429118.1|795490_798505_+	translation initiation factor IF-2	E3T4N3	Cafeteria_roenbergensis_virus	1.6e-22	24.3
WP_080808813.1|798504_799599_+|tail	low-complexity tail membrane protein	NA	NA	NA	NA
WP_080808810.1|799828_800029_+	hypothetical protein	NA	NA	NA	NA
WP_088429120.1|800225_801110_+	DUF4349 domain-containing protein	NA	NA	NA	NA
WP_080808801.1|801702_802617_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_080808798.1|802691_803111_+	CopY family transcriptional regulator	NA	NA	NA	NA
WP_080808795.1|803110_803962_+	M56 family peptidase	NA	NA	NA	NA
WP_088429122.1|803996_804188_-	high light inducible protein	NA	NA	NA	NA
WP_088429124.1|804292_804763_-	hypothetical protein	NA	NA	NA	NA
WP_088429126.1|804870_805626_-	hypothetical protein	NA	NA	NA	NA
WP_080808787.1|807837_808392_-	hypothetical protein	NA	NA	NA	NA
WP_080808785.1|808397_808982_-	Uma2 family endonuclease	NA	NA	NA	NA
WP_080808782.1|809407_810589_+	hypothetical protein	NA	NA	NA	NA
WP_080808779.1|810790_811069_+	hypothetical protein	NA	NA	NA	NA
WP_080808776.1|811216_811912_-	hypothetical protein	NA	NA	NA	NA
WP_088429129.1|811964_813031_-|transposase	ISKra4 family transposase	NA	NA	NA	NA
WP_080807200.1|813049_814282_-	hypothetical protein	NA	NA	NA	NA
WP_080808773.1|814400_816113_-	RAMP superfamily protein	NA	NA	NA	NA
WP_080808770.1|816344_816767_-	hypothetical protein	NA	NA	NA	NA
WP_080808767.1|816785_817835_-	type III-B CRISPR module RAMP protein Cmr4	NA	NA	NA	NA
WP_080808766.1|817964_819155_-	hypothetical protein	NA	NA	NA	NA
WP_080808763.1|819175_821074_-	hypothetical protein	NA	NA	NA	NA
WP_080808759.1|821386_822100_-	hypothetical protein	NA	NA	NA	NA
WP_088429131.1|822428_823046_+	Uma2 family endonuclease	NA	NA	NA	NA
WP_080808756.1|823943_824363_+	hypothetical protein	NA	NA	NA	NA
WP_088429133.1|824591_825596_+	CRISPR-associated endonuclease Cas1	NA	NA	NA	NA
WP_080808744.1|825595_825871_+	CRISPR-associated endonuclease Cas2	NA	NA	NA	NA
WP_088431512.1|833018_833363_+	DUF559 domain-containing protein	NA	NA	NA	NA
WP_080806623.1|834015_835062_-|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
WP_088429135.1|835427_836579_-|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_080809504.1|837129_838302_-|transposase	transposase	NA	NA	NA	NA

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NZ_CP021983|4789098:4799086|DBSCAN-SWA
GTCAAGTCAGAGCAGCTACCGGATGGTCTGCCAGCACCTTAGCCAGGTATTGCCCAGTGTAGGAGTGGGGCTGCTGGGCCAGCTCTTCTGGAGTACCGACGGCGATGACTTCACCGCCATGCTCACCGCCCTCCGGTCCCAGGTCGATGACCCAGTCGGCACAGCGAATCACATCCAGGTTGTGCTCGATCATCAGCACCGAGTTGCCCTTATTCACCAGGCGCTGCACCACATCCAACAGCTTGTGCACATCGTAAAAAGACAGGCCGGTGGTGGGTTCGTCGATCAAATAAAGGGTCTTGCCGGTGGCGCGGCGGGCCAGTTCCGAGGCCAGCTTCATCCGCTGCGCCTCGCCTCCAGAGAGGGTGGGGGCCGTCTGCCCCAGGCGAATATAGCCCAGGCCCACATCCACCATGGTCTGTAGTCGGCTGGCCGCCTTGGGAATATTCTGGAAAAAGTCCAGGGCTTCTTCTGCCGTCATGTTGAGTACATCGGCAATGGTGCGGTCCTTATATGTCACCTGCAGGGTCTCCCGGTTATAGCGGGCCCCTTTGCAGACTTCGCACTGCACGTAGACATCCGGCAGGAAGTTCATCTCGATCACATTCACGCCCTGGCCGCTGCAGGCTTCGCAGCGTCCCCCCTTGACGTTGAACGAAAACTGCCCCGCCTTGTAGCCGCGGGCCTTAGCCTCGATGGTTTCGGTGAAGAGGTTGCGGATGACGTCGAACACTCCAGTGTAGGTGGCCGGATTAGAGCGGGGTGTGCGGCCAATGGGGGATTGGTCGATGACGATGACTTTATCCAGGGCCTTGAGTCCCGAGAGCTTGTCTAGATCTTTCGGAAAGGGGACTTTGCTGCCGAAGTGGTGCTGCAGGGCCGGGTAGAGCAAGTTGTTCACCAGGGTAGACTTGCCGGAGCCCGAGACCCCAGTCACACAGACGAACTGCCCCAACGGAATCTCCACGTCGATATGCTTCAGGTTGTTGCGACGGGCCCCGTGGAGTTTCAGGCTGCGGCGATTGCCGGGCCGCCGCTGGGCTGGGGTGGGAATCACCAAGCGCCGGGCCAGATAGGCCCCAGTCACAGAATCTGCAGCCTGAGTCAGGTCGTCGATATGGCCTTGGACCACGATGTGGCCGCCGTGGATACCAGCACCGGGACCAATATCCACTAGGTGGTCGGCAGCCCGAATGGTGTCTTCATCGTGCTCCACCACGATCAGGGTATTGCCCAGATCCCGCAGCCGGGTCAGGGTGCGCAACAGGCGGTCATTGTCACGCTGGTGCAAGCCGATGCTGGGCTCGTCTAGGACATAGAGGACGCCGGTGAGGCCGGAGCCAATCTGGGTGGCTAGGCGAATACGCTGGGCCTCGCCGCCGGAGAGGGACATGGCGGTGCGGTGTAGGGTCAGATAGTCGAGGCCTACGTCGATGAGGAATTGTAGCCGGGCCTTGATTTCCTTTAGCACTAGTTCACCGATCTGGCGTTGGCGCCAGGATAGTAGCGGCGTTCCCTCATCACCGGCCAGGGTCTTGATCCGCTCCAGGCATTTGCGAATGGAGACGTTGGTCAGATCGAGCACATTGTAAGGGCCCATGCGTACGGCCAGGGATTCGGGCTTGAGCCGGGCTCCCTGACACACGTCACAGGGCTGATCGATCAAGTATTTTTCCAGCTTTTGCTTGTAGAGTTCGGAGCTGGCATCGCGATACTGGCGCTCTAAGATGGGCAGCACCCCTTCATAGCGCCGTTCATAGCCTTTGCGATCCCGATAGCGGGAGTCGGTTTCGATGTAGATCTTCTCGTCGCAGCCGTAGAGTACGATCTGCTGCTGCTCCTGGGTCAGCTGTTCCCAGGGGGTTTGAATCTGGAAGCCAAAGGCCTGGCCAACGCTGTAGAGCAGCGAGAAATAATAGGTGTTGTCCTTTTCCGACCAGGGGGCAATAGCGGCGTAGACCGGCAGTTTGGGATCGGGCACCACTAGATCGGCGGCGAAGGTGGGTAAGTTGCCCAAGCCATGGCAATGGGGACAGGCGCCGTAGGGGGAGTTGAAGGAGAACAGCCGTGGCGACAGCTCTTCCATGACGGCCCCGTGTTCCGGGCAAGCGAAGTTCTCCGAGAAGACCAACTCCGGCGGTAGGCCATAGGATGCTTCCCCTTCTGCCGCCTGGGGCAGTGAGTCAGACAGAGATTGAGATCGCAGCGGCACCACCTTAGACTCGCCAGACTGCCCCGCTTGAGCCCGATTGCGGTCTGGCAAAACGTCGATGACGGCAATGCCACTGGAGCGCTTCAGGCAGGTGGCCAGGGAGTCAGCCAGCCGCTCTTGCAGCCCTGGCTTTTTCACCAGTCGGTCTACCACTACTTCGATGGTGTGGGCCTGGTTTTTGTCCAGCTCGATGGCATCGGTGAGGTCACGGATGTCGCCGTTGACCCGGACTCGCACAAATCCCTCCGAGGCCAGAGCGGACAGCAGCTTCTTGTGGGTGCCCTTCTTGCCCCGCACCACCGGGGCCAACAGCTGAAACCGGGTGCCGTCTGGCAATTCCAGCACCCGGTCGATCATCTGGTCGATGGTCTGGGGGGCGATGCTGCGATCGCATCGGGGACAGTGGGGCTCCCCGGCTCGGCCAAACAGCAACCGCAAATAGTCATAGATCTCCGTCACCGTACCCACCGTAGAGCGGGGGTTATGGGAGGTGGACTTCTGGTCGATGGAAATGGCCGGGCTCAGCCCCTCGATGGCATCGACATCGGGCTTGTCCACCTGGCCCAAAAACTGGCGGGCATAGGCACTGAGGGACTCCACATAGCGTCGCTGCCCCTCGGCAAAAATCGTATCGAAGGCTAGGGACGACTTGCCGGAGCCTGATACCCCCGTAAACACAATCAGCTGATTCCGGGGCAGATCCAGGTCAATATCTTTGAGATTGTGTTGTCGCGCCCCCCGTACCCGGATCACATTATCATCATCAGGAGAGGCGGGCCGACCCAGCACTCGTTGCCGCCACTGCCCTACCGTTGTGGGCCTGGTCTAGAAGAGAATCGCGCTGGGGCATAGCCGCTCAAGGGATGGATCTAGCATCGTAGGCAATACAGTTCTTAATATAGTAGCCCGCTCACGGAAAGCAAGGGGAATCTGTTCTCCGCAGCAGTAAGTTGGCGCCAGTGCGGAAATGGACAGTCTCCCGTTGAAGATCCTCTGATGCCTGGCGGCAAAGCGGCTGATTCACAGTCCCTATGGCGATCCTATAGACACGCCACGTCCCTGGGGATCTGGGAAATCCCATGGCCAGCTCCTTGATGGCCAATGATGGCGCCATCAGCATCTACTGTGTAAGAAAAGTCAGGGGCATCTTCAGGCCCAGGCGGAATGAGTCTCTCCGTCTGCCTGTCTATCAGTAACCAGTCAGTGTACTAATCCGCCGGTTGGGTAGCGTTTAGCCTAGGCGCGCTTTCCCAGGGTTAACGTTGTCTAACCCAGGCAACCATTTGTGACCGCCAAGGAGTCTACCATGTCGTCCGGTCGCCATGCTCATCTACCTGGGAGCCGCCGCCAGGGACTACTGATCACAGCCTTGTCCTTGGCCCCCTCCCAGCTCATCGGCAGTGCGTTCAATATTTGGTACAACCTCAGCCATATTCAACCGCTGCTGACCCCGGTCCAGCATCAGGTGTTTCAAGAGGCGATTGGGGTCTTTAATCTGACGGTGTATCCCGCCGCCATGGTCTTTTGGTTCTGGCTGTTTTTCTCCCTGCGGCCCGTGGCTAGTCGTCTGCTGGCGGATCAGCCGGTACCGCCTGCCCGACTGATGGCGGCCCAACGGCGGGTGATCAACCTACCCTGGTTGTCCATGCTGGTGGCTGGGATTGGCTGGCTCTTATGTATCCCGGTGTTTCTGACGGTGCTAGAGCGGACCGCTGACCCCTTGGCCCCCCAGGTGTGGATTCACCTGCCCATTTCCATCTTGATTTCCACGGTGATTGCCCTCACCCACGGCAGCTTCACCATCGACCTCCTCAGCCAACGGTTGCTCTATCCCCTCTTTTTTCGCCAGGCCCATCCGGCTGAGATTCCCGGGGCCTATCCCCTCACCCTGAAAAATCGCATTACCTTCTGGGCGGTCTCCGCCAGCATCTGCCCCATTGCTTCCTTGTTGTTGCTGGAGTTTGTGCCCAATGCCAACAATATGGGGTCGTTTTCTCTGTTGGTGGGGCTGTTGGGCATGGGGTTTAGCCTGGTCAGTGCCTGGATGCTGTCTCAGCTGGTGGTGGAGCCGGTGGACATGCTGCAGGATGCGGCTAAACGGGTTGCCCAGGGTGATTTAACGGTGCAAATTACCCAACCCCGGGGGGATGAGTTCGGCACCTTAATCGATGCCTTCAATGCCATGGTGACGGAACTGCGAGACAAGCAGCATCTGTTGGAAACCTTCGGCCGCCATGTGGGAGAACAGGCGGCCCGGCAGATTCTGCAGCAGGATCCGGGGTTGGGAGGGACCGAACAGGTGCTGACGGTGATGTTTGCCGATCTGCGAAACTTTACCGCCCGCTGCAATCACAGTACCCCCCAGGAGATCGTGGCCCTACTCAACCTCTTCTTGGCTGACATGGTGGAGATCGTGGAGCACCAGCATGGGGGCATGGTGAATAAGTTTCTGGGGGATGGGTTTATGGCCCTATTCGGCGTGGGGGAGCCGGACGGCGACCATGCTGCCCGTGCGATCGCATCGGGTCAAGCCATGCTGGGCAGTTTAGAACAGCTGAATCGAATCTTGGCCGAGAAAAACATCGCGCCGCTGGCCATTGGCATCGGCCTGCACACCGGCCCGGCAGTGGTGGGGAGCATTGGCTCCCCCCAGCGGTTAGAATACACCGCCATCGGCAGCACGGTGAATATTGCCTCTCGGGTAGAAAGCCTGACCAAGACCGTTGGCTATCCCCTGCTGTTCACCGCCGCCACCCGTGTCGCCCTGCCCGCGGATATACCCCTGCAGGCCCTGCCCCCCCAGCCAGTGCGGGGGTTAGATCAGCCGCTGCCGGTGTTCTCCCTGACCCAGTCGGTACGCCTGGACAGGAGTGCCCCTGGCACAGCGAAGGGTAATAGGTCCGGTGAGTCTGGTGCTTAGCCCTTAAAGACATCCCGGGTAAATAGCACCAATACGGCTCCGAACACCATAGCGGCAAGTGCAAAATCCATCGACTCCTCCTTAAATCGCAATCAGTGACAAATAGGTGCATCAACGGTGACGACGGTAGCGCTATATCTAACCAAACCCCTTCCTGAGGTTAAGACTGCCGCAGCACTCCAGATCAGTGCATCTCAGAGGCCTTAGCAAAGCCTTCGTAGTCCCGCTGCGCTTTCTTTACCCAGGCCGTCATGCACCTAAATTCAGCCTAGCCGGATCCTCAAGGTTTCTTATGGGGGGCCAAGCCCATCTCCCTATCCCCACCCCCCCCTGGGCATAGAAACCCAGAGCACTTTAGCAGTATGGTCATGCTGTCATCCATGACAGACATGACAGATTGAATTCATGACAGATTGAGAGGAGAGGATCACCACCATGGCTTACCAACTACCGGCCCTGCCCTACGACTACAGTGCCTTAGAACCCTACATTTCTAAGACCACCCTAGAGTTCCATCACGACAAACATCACGCCGCCTATGTGACCAAGTTCAACAATGCGGTAGCGGCAACAGAATTAGCCAGCCAGCCCATTGAGCAGGTGATTAAAACTGTGGCCAAAGATCCCACCAAGACAGGGATTTTCAATAATGCCGCCCAAGCCTGGAATCATACCTTTTACTGGAACAGCATGACCCCCGGTGGCAGTCAGCCCAGTGGCAAATTAGCCGAGAAAATTGAGACTGATTTCGGCAGTTTTGACCAGTGTGTCGAGGCCTTTAAAACAGCCGCCGCCACCCAATTTGGCAGCGGCTGGGCCTGGCTGGTGCTAGAGGATGGCCAGCTCAAGGTAACCAAAACGGCCAATGCCGACAATCCCCTTACCCATAATCAAGTGCCCCTGTTAACCATGGATGTGTGGGAACACGCCTATTATTTGGATTATCAAAACAGACGGCCCGACTACATCCAGACCTTTCTACAGCATCTGGTCAATTGGGACTTTGCTGCTGAAAATCTGGCAGCGGCCCAATAATTACCATGATTCTAGACCCTGACTATCCCCATATTGTCCTCACCTTCACCTACCGAGGTTGGTGTATTCAGATCGACCAGGGGGAATGGGACGGCGAGGTCACCTATGGTGCCTGGGCTAATCATGACCAGGGCTGTGCGGTGGCCGTCCCCTATGCCCGCTCCCGCACCGAGGCCGTGCTGCAAGCCAAGCAATGGGTGAATCGCCGCCTGCAGGGGATGCAGTCGTCCCAGTAATGTTAGGGGGCTGGTGCCATCGTCAGGACCAGATTCCGGTAGCCCTTGGCGTACAATAGCTTCGCTGCAGGAGGTCACGACTATGGGCTACTTTCGACCTGCCATTGAGGCCATGACCGGCTATGTGCCAGGGGAACAGCCGCCGCCGGGGACGCCGGTGATCAAGCTCAACACCAATGAAAATCCCTATCCGCCGTCTCCCCAGGCCATGGCAGTGCTGCACAGCCTGGATAGTGAGTGGTTGCGGCGCTATCCCGATCCCTATGGCCGTGAGGTGCGCCAGGCCGTGAGTCAGGGGCTGCAGGTACCAGAAGATTGGGTCATTGTTACCAACGGCAGCGATGATCTGCTCAATATTTTGATTCGGGCCTGTGCCGAAGGCCACAGCCGCCCCGTTGCCTATCCCACCCCCACCTATGTGCTCTACCGCACTCTGGCGGCCCTGCAACCGGCCCAGGTGATCGAGATCCCCTACCCAGAGAACTATCGACTACCGCTCGACGAGCTCGTTGCCGCCCAAGCCGCCGTCACCCTGATCGCCAGCCCCAACAGCCCCTCCGGCCACAGTGTTCCTGTGGTTGATCTGGGCCGACTAGCCCAGCGGTTGTCGGGGATCTTGGCCATTGACGAAGCCTATGTGGACTTCGCCGACACCTCAGCCCTAGAGTTAGTGCAGCAGCATGCCAATGTTCTGCTGCTGCGCACCCTATCCAAGGGCTATGGCCTAGCCGGGCTGCGGCTGGGGTTCGGCCTGGCTCAACCGGAGTTAATCGCGGGTCTGTTTAAAGTGAAAGACAGCTACACCGTCGATGCCGTGGCCATGGCCGTCGGTGCCGCTGCCCTGCGAGACCAAGCTTATAAGGATCAACGAGCCAAGCAGATCAAGGCCAGCCGCACCCGCCTAATCCGGGAGCTGCGACGCTTGGGCTTCACCGTCCCCGACTCCCAGGGCAATTTTGTCTTGGCCACCGTTCCTATGGGATCTGCCCAGGCCTTGACCCAGGCCCTGAAGCAGCGGGGCATTCTAGTGCGATACTTTAACCAACCGGGCCTGGATGACAAGCTGCGGATTACCATTGGCACCGAGGCGCAAAATCAACAGTTGCTGGAGATCTTGCAGGCATTGTTGGCCAATGCCCATTCCCTCAATTGACGCGATTCCCTATTTATAGCGTTGGCCAGTCAGCTGAGGACATAGCTGATCGCCCAATAGCCTAGCCTAGGAAGGCTGACTGGCTCGCCACCGCACACAGCATGATGGCGGTGGCTATAACGACAGGGGCGCGAGCGGCTTCCCATCCCAGTAGAGCAGCCTTGCGATCTAGGCCCCAGCGGTAGCCTCCCAAGGCCCCCGATTCTCGAATCACCCGATGGCAGGGAATCAAATAGGCAATGGGGTTGCGACCGATGGCACTGCCCACGGCCTGGCAAGCGGTGGGGCGACCGATGAGGGCGGCCACGGTGCCATAGGTCACTAGCCCTCCCGGCGGAATCTGCAGCAAGGCTTGCCACACCTGCACTTGGAAGTTGGTGCCCCGTACCAGCAGCGGCAGGGGACGGGGGAGAGACGAATGGTCATCGGGGGGGCGATGGCCCTTCAGGGCTGCTCCAGCCCCTCTAGGATGGCTTAGCCGACCATCGCCTCCCCAGGGAATCTGGCTCCAGCAGAGCCTGACTGCATCATCGTCTCGAATCAGAGTTGCCTGGGGCCAAGCCTGGCCCAGACCAGCCACGGCCTGGGTCACCTCATCAGCGAACTGGAGATGGCAAATCCCCCGGTCCGTGATCCCCATCAAGGCTAAGCCCACAGGCGTGGCATGCATACCGTAGTAAATCTGTAACCCCTGGCCCTTACCCTTGGCCTCACCCGGGGTCATGGCCTGCAGCGTCACAAACAGATCGTGGAGTCGGCCTGGCCCCGACAGCCCCACCTCCTGGCTCAGGTGTAACAGGCTCTGGGTGTTAGCCAGGCGAGCCTTAGCGGCTTCCAGGGTGAGGCAGCGCAGAAACCGCTTGGGACTGAGCCCGACCCAGCGAGTGAAGAGCCGCTGAAAGTGATACTCGCTCAAGTTGACCTGGGCAGCAATGGTGGCTAGATCAGGCTGTTCATGGCGATGCTCGACCATGAAGTGAATAGCCCGGGCCATGGCAGCATAGGTATCTGAGTGGGTGGCTGTGGAGTCGTCCGTGAGTTCAGTGACCATAAGGGTTGCAAGAACCGATGGCTTTACTTTACCTAGGCCATCACCACGACACCACCCGATTCTTGCCAAGTGTGTTCTCCCCATTTCCCCCTTCAACCCCTTCAACTTCTTCCTCTGAGACCACGAGCTTGTGTGTTACACTGATGAATCGTGGATAGGCGGGTCGGTGCCCGAGTGGTTAATGGGGGCGGACTGTAAATCCGCTGGCTATGCCTACGCTGGTTCGAATCCAGCCCGGCCCATCCACATCGCTGCCCATGTAGCTCAGTGGTAGAGCACACCCTTGGTAAGGGTGAGGTCACGAGTTCAATCCTCGTCATGGGCTCTGGATTCAACCATCCTCTGAGTCAGATAAACCGGATATCGGATCAGGAGACGGAGGTCATGGCCGGGGAGTATTGGTAGTACTCGCAGTACCAGCGGACGAATCGCTCGATGCCGGCTTCGATGGGGGTGTTGGGCTGAAAGCCGACGGCTCGCATCAGATCGTCCACATCGGCGTAGGTGGTGGGTACATCTCCCGGTTGCATCGGCTTCATGATTTTTTGGGCGGGCTTGCCCATGGCGGCTTCAATCACCTCAATGAAGCGAAGTAGCTCTACGGGTTGATGATTGCCGATGTTATAGACCTGGTAAGGGGCTCGGCTGTTGAGGCTGTCGGCGGCGATGGGGGGTGGGGGGGTGCCCATGACTCGCACCACGCCTTCGACGACGTCGTCGATATAGGTGAAATCCCGCTGCATCTGGCCGTGATTATAAACTTCGATGGGGTGTCCCTTTGCGATCGCATCCACAAACTTGAAATAGGCCATATCGGGCCGACCCCAAGGGCCATAGACCGTGAAGAAGCGCAGGCCTGTGGTGGGGATCTGGTAGAGATGACTGTAGGCATGGGCCATCAGCTCATTGGCCTTTTTGGTAGCGGCATAGAGCGAGACCGGGTGATCTACGGCATCGCTGACGGAGAAGGGCACCTTGCGATTGGCCCCGTAGATGGAACTGGACGAGGCATAGACCAGGTGCGCCACCTGCCCGTGGCGGCAGCCCTCCAGGATATTCAAAAACCCTGAGAGATTGCTGTCGCCGTAGGCAAAGGGATTACTGAGGGAATAGCGCACCCCGGCTTGGGCGGCCATGTGCAAGACATAGTCGAAGGACTGGGTCTGGAATAACTGCTGCATGCCTTCGCGGTTGGCTAGGTCCAGCTTTTCAAAGGTAAAGCCGGGATAGGGGGTGAGCTGGGCGATGCGATCGCGCTTGAGCCGCACATCGTAGTAATCATTGAGATTATCGATGCCATACACCTGCACTCCATCTGCCAGTAACCGTTGGGCTAAGAAAAATCCGATAAACCCCGCTACCCCAGTCACCAATACTTGCAT

Protein sequences of DBSCAN-SWA_3

>NZ_CP021983|4789098:4799086|4796714_4797704_-|WP_080813573.1|DBSCAN-SWA
MVTELTDDSTATHSDTYAAMARAIHFMVEHRHEQPDLATIAAQVNLSEYHFQRLFTRWVGLSPKRFLRCLTLEAAKARLANTQSLLHLSQEVGLSGPGRLHDLFVTLQAMTPGEAKGKGQGLQIYYGMHATPVGLALMGITDRGICHLQFADEVTQAVAGLGQAWPQATLIRDDDAVRLCWSQIPWGGDGRLSHPRGAGAALKGHRPPDDHSSLPRPLPLLVRGTNFQVQVWQALLQIPPGGLVTYGTVAALIGRPTACQAVGSAIGRNPIAYLIPCHRVIRESGALGGYRWGLDRKAALLGWEAARAPVVIATAIMLCAVASQSAFLG
>NZ_CP021983|4789098:4799086|4798072_4799086_-|WP_080813572.1|DBSCAN-SWA
MQVLVTGVAGFIGFFLAQRLLADGVQVYGIDNLNDYYDVRLKRDRIAQLTPYPGFTFEKLDLANREGMQQLFQTQSFDYVLHMAAQAGVRYSLSNPFAYGDSNLSGFLNILEGCRHGQVAHLVYASSSSIYGANRKVPFSVSDAVDHPVSLYAATKKANELMAHAYSHLYQIPTTGLRFFTVYGPWGRPDMAYFKFVDAIAKGHPIEVYNHGQMQRDFTYIDDVVEGVVRVMGTPPPPIAADSLNSRAPYQVYNIGNHQPVELLRFIEVIEAAMGKPAQKIMKPMQPGDVPTTYADVDDLMRAVGFQPNTPIEAGIERFVRWYCEYYQYSPAMTSVS
>NZ_CP021983|4789098:4799086|4795269_4795500_+|WP_088431044.1|DBSCAN-SWA
MILDPDYPHIVLTFTYRGWCIQIDQGEWDGEVTYGAWANHDQGCAVAVPYARSRTEAVLQAKQWVNRRLQGMQSSQ
>NZ_CP021983|4789098:4799086|4792615_4794229_+|WP_088431042.1|DBSCAN-SWA
MSSGRHAHLPGSRRQGLLITALSLAPSQLIGSAFNIWYNLSHIQPLLTPVQHQVFQEAIGVFNLTVYPAAMVFWFWLFFSLRPVASRLLADQPVPPARLMAAQRRVINLPWLSMLVAGIGWLLCIPVFLTVLERTADPLAPQVWIHLPISILISTVIALTHGSFTIDLLSQRLLYPLFFRQAHPAEIPGAYPLTLKNRITFWAVSASICPIASLLLLEFVPNANNMGSFSLLVGLLGMGFSLVSAWMLSQLVVEPVDMLQDAAKRVAQGDLTVQITQPRGDEFGTLIDAFNAMVTELRDKQHLLETFGRHVGEQAARQILQQDPGLGGTEQVLTVMFADLRNFTARCNHSTPQEIVALLNLFLADMVEIVEHQHGGMVNKFLGDGFMALFGVGEPDGDHAARAIASGQAMLGSLEQLNRILAEKNIAPLAIGIGLHTGPAVVGSIGSPQRLEYTAIGSTVNIASRVESLTKTVGYPLLFTAATRVALPADIPLQALPPQPVRGLDQPLPVFSLTQSVRLDRSAPGTAKGNRSGESGA
>NZ_CP021983|4789098:4799086|4789098_4792098_-|WP_088431040.1|DBSCAN-SWA
MLGRPASPDDDNVIRVRGARQHNLKDIDLDLPRNQLIVFTGVSGSGKSSLAFDTIFAEGQRRYVESLSAYARQFLGQVDKPDVDAIEGLSPAISIDQKSTSHNPRSTVGTVTEIYDYLRLLFGRAGEPHCPRCDRSIAPQTIDQMIDRVLELPDGTRFQLLAPVVRGKKGTHKKLLSALASEGFVRVRVNGDIRDLTDAIELDKNQAHTIEVVVDRLVKKPGLQERLADSLATCLKRSSGIAVIDVLPDRNRAQAGQSGESKVVPLRSQSLSDSLPQAAEGEASYGLPPELVFSENFACPEHGAVMEELSPRLFSFNSPYGACPHCHGLGNLPTFAADLVVPDPKLPVYAAIAPWSEKDNTYYFSLLYSVGQAFGFQIQTPWEQLTQEQQQIVLYGCDEKIYIETDSRYRDRKGYERRYEGVLPILERQYRDASSELYKQKLEKYLIDQPCDVCQGARLKPESLAVRMGPYNVLDLTNVSIRKCLERIKTLAGDEGTPLLSWRQRQIGELVLKEIKARLQFLIDVGLDYLTLHRTAMSLSGGEAQRIRLATQIGSGLTGVLYVLDEPSIGLHQRDNDRLLRTLTRLRDLGNTLIVVEHDEDTIRAADHLVDIGPGAGIHGGHIVVQGHIDDLTQAADSVTGAYLARRLVIPTPAQRRPGNRRSLKLHGARRNNLKHIDVEIPLGQFVCVTGVSGSGKSTLVNNLLYPALQHHFGSKVPFPKDLDKLSGLKALDKVIVIDQSPIGRTPRSNPATYTGVFDVIRNLFTETIEAKARGYKAGQFSFNVKGGRCEACSGQGVNVIEMNFLPDVYVQCEVCKGARYNRETLQVTYKDRTIADVLNMTAEEALDFFQNIPKAASRLQTMVDVGLGYIRLGQTAPTLSGGEAQRMKLASELARRATGKTLYLIDEPTTGLSFYDVHKLLDVVQRLVNKGNSVLMIEHNLDVIRCADWVIDLGPEGGEHGGEVIAVGTPEELAQQPHSYTGQYLAKVLADHPVAALT
>NZ_CP021983|4789098:4799086|4794664_4795264_+|WP_080813577.1|DBSCAN-SWA
MAYQLPALPYDYSALEPYISKTTLEFHHDKHHAAYVTKFNNAVAATELASQPIEQVIKTVAKDPTKTGIFNNAAQAWNHTFYWNSMTPGGSQPSGKLAEKIETDFGSFDQCVEAFKTAAATQFGSGWAWLVLEDGQLKVTKTANADNPLTHNQVPLLTMDVWEHAYYLDYQNRRPDYIQTFLQHLVNWDFAAENLAAAQ
>NZ_CP021983|4789098:4799086|4795582_4796653_+|WP_080813575.1|DBSCAN-SWA
MGYFRPAIEAMTGYVPGEQPPPGTPVIKLNTNENPYPPSPQAMAVLHSLDSEWLRRYPDPYGREVRQAVSQGLQVPEDWVIVTNGSDDLLNILIRACAEGHSRPVAYPTPTYVLYRTLAALQPAQVIEIPYPENYRLPLDELVAAQAAVTLIASPNSPSGHSVPVVDLGRLAQRLSGILAIDEAYVDFADTSALELVQQHANVLLLRTLSKGYGLAGLRLGFGLAQPELIAGLFKVKDSYTVDAVAMAVGAAALRDQAYKDQRAKQIKASRTRLIRELRRLGFTVPDSQGNFVLATVPMGSAQALTQALKQRGILVRYFNQPGLDDKLRITIGTEAQNQQLLEILQALLANAHSLN

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_088431040.1|4789098_4792098_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	8.8e-284	49.6
WP_088431042.1|4792615_4794229_+	adenylate/guanylate cyclase domain-containing protein	A0A2H4N7Z5	Lake_Baikal_phage	1.1e-22	29.8
WP_080813577.1|4794664_4795264_+	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	2.4e-44	45.6
WP_088431044.1|4795269_4795500_+	hypothetical protein	NA	NA	NA	NA
WP_080813575.1|4795582_4796653_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	1.7e-16	24.5
WP_080813573.1|4796714_4797704_-	hypothetical protein	A0A2P1EL10	Moumouvirus	3.9e-15	48.2
WP_080813572.1|4798072_4799086_-	NAD-dependent epimerase	A0A2K9KZK0	Tupanvirus	8.7e-18	25.0