CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP019721	Veillonella parvula strain UTDB1-3 chromosome, complete genome	10 crisprs	DEDDh,csa3,cas6,csm3gr7,csx19,csx10gr5,cas10,csx20,cas1,cas2,csx1,cas3	3	2	6	2

1. NZ_CP019721

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP019721_1

• CRISPR_ID: NZ_CP019721_1
• CRISPR_location: 309077-309182
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP019721_1

Consensus_repeat	Method
CCCCTGTGTTGATGTAACTATGGTTAGTCGCAT	CRISPRCasFinder

spacers of NZ_CP019721_1

>1.1|309110|40|NZ_CP019721|CRISPRCasFinder
TCCATTCAATGGTATTCTTATCAAAGGCCAGCGTTGTAGT

CRISPR arrays and Neighbor proteins around NZ_CP019721_1

CRISPR arrays

The CRISPR arrays of NZ_CP019721_1

>merge|NZ_CP019721|1|309077-309182|CRISPRCasFinder
CCCCTGTGTTGATGTAACTATGGTTAGTCGCATTCCATTCAATGGTATTCTTATCAAAGGCCAGCGTTGTAGTCCCCTGTGTTGATGTAACTATGGTTAGTCGCAT

>NZ_CP019721|1|1|309077-309182|CRISPRCasFinder
CCCCTGTGTTGATGTAACTATGGTTAGTCGCAT	TCCATTCAATGGTATTCTTATCAAAGGCCAGCGTTGTAGT
CCCCTGTGTTGATGTAACTATGGTTAGTCGCAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019721.1|WP_077707700.1|311336_311642_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707705.1|316856_320051_-|phage-tail-protein	unknown	unknown	gnl|CDD|274008
NZ_CP019721.1|WP_077707707.1|320659_321622_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707696.1|308359_308911_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707706.1|320040_320226_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707699.1|310351_311350_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707702.1|315604_315931_-|C40-family-peptidase	unknown	unknown	gnl|CDD|366353
NZ_CP019721.1|WP_004697615.1|320369_320648_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707691.1|303764_304103_-|branched-chain-amino-acid-transporter-permease	unknown	unknown	gnl|CDD|224601
NZ_CP019721.1|WP_077707692.1|304861_306028_-|iron-containing-alcohol-dehydrogenase	unknown	unknown	gnl|CDD|224890
NZ_CP019721.1|WP_077707695.1|307974_308367_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707693.1|306180_306420_-|hypothetical-protein	unknown	unknown	gnl|CDD|340158
NZ_CP019721.1|WP_187658826.1|306857_307484_-|hypothetical-protein	unknown	unknown	gnl|CDD|224117
NZ_CP019721.1|WP_077707694.1|307398_307974_-|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl|CDD|376556
NZ_CP019721.1|WP_077707701.1|311650_315601_-|hypothetical-protein	unknown	unknown	gnl|CDD|227076
NZ_CP019721.1|WP_077707703.1|315914_316520_-|DUF1833-family-protein	unknown	unknown	gnl|CDD|227018
NZ_CP019721.1|WP_077707689.1|301583_302699_-|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|273776
NZ_CP019721.1|WP_004694895.1|304095_304761_-|AzlC-family-ABC-transporter-permease	unknown	unknown	gnl|CDD|129446
NZ_CP019721.1|WP_077707698.1|310009_310336_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707690.1|302810_303662_+|aldo/keto-reductase	unknown	unknown	gnl|CDD|381359

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP019721.1|WP_077707705.1|316856_320051_-|phage-tail-protein	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	4.7984e-05
NZ_CP019721.1|WP_077707702.1|315604_315931_-|C40-family-peptidase	gnl|CDD|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	2.95885e-13
NZ_CP019721.1|WP_077707691.1|303764_304103_-|branched-chain-amino-acid-transporter-permease	gnl|CDD|224601	COG1687, AzlD, Predicted branched-chain amino acid permeases (azaleucine resistance) [Amino acid transport and metabolism].	1.49165e-31
NZ_CP019721.1|WP_077707692.1|304861_306028_-|iron-containing-alcohol-dehydrogenase	gnl|CDD|224890	COG1979, COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion].	0
NZ_CP019721.1|WP_077707693.1|306180_306420_-|hypothetical-protein	gnl|CDD|340158	pfam17443, pXO2-72, Uncharacterized protein pXO2-72. This is a family of unknown function found in Bacilli.	0.00146405
NZ_CP019721.1|WP_187658826.1|306857_307484_-|hypothetical-protein	gnl|CDD|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	0.000517393
NZ_CP019721.1|WP_077707694.1|307398_307974_-|N-acetylmuramoyl-L-alanine-amidase	gnl|CDD|376556	pfam01510, Amidase_2, N-acetylmuramoyl-L-alanine amidase. This family includes zinc amidases that have N-acetylmuramoyl-L-alanine amidase activity EC:3.5.1.28. This enzyme domain cleaves the amide bond between N-acetylmuramoyl and L-amino acids in bacterial cell walls (preferentially: D-lactyl-L-Ala). The structure is known for the bacteriophage T7 structure and shows that two of the conserved histidines are zinc binding.	0.00865105
NZ_CP019721.1|WP_077707701.1|311650_315601_-|hypothetical-protein	gnl|CDD|227076	COG4733, COG4733, Phage-related protein, tail component [Function unknown].	1.48444e-29
NZ_CP019721.1|WP_077707703.1|315914_316520_-|DUF1833-family-protein	gnl|CDD|227018	COG4672, gp18, Phage-related protein [Function unknown].	1.00486e-11
NZ_CP019721.1|WP_077707689.1|301583_302699_-|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl|CDD|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	8.29236e-41
NZ_CP019721.1|WP_004694895.1|304095_304761_-|AzlC-family-ABC-transporter-permease	gnl|CDD|129446	TIGR00346, Uncharacterized_membrane_protein_HI_1738, 4-azaleucine resistance probable transporter AzlC. Overexpression of this gene results in resistance to a leucine analog, 4-azaleucine. The protein has 5 potential transmembrane motifs. It has been inferred, but not experimentally demonstrated, to be part of a branched-chain amino acid transport system. Commonly found in association with azlD. [Transport and binding proteins, Amino acids, peptides and amines].	1.34297e-47
NZ_CP019721.1|WP_077707690.1|302810_303662_+|aldo/keto-reductase	gnl|CDD|381359	cd19133, AKR_AKR5F1, the AKR5F family of aldo-keto reductase (AKR). Klebsiella sp. 2,5-diketo-D-gluconic acid reductase (2,5-DKG reductase) is a founding member of aldo-keto reductase family 5 member F1 (AKR5F1). It catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).	1.75813e-130

Protein sequences

>NZ_CP019721.1|WP_077707696.1|308359_308911_-|hypothetical-protein
MDILNDILVMLISGVSHEHIVSMGVIIILTTVLLFIDAAQRITTEVLRYNKDNHRNNTPITLLTTLAWYGWGKGGYVDATTGLKRRYLMSERLRSDLLTKLCVQYPAWMVLSVVFESLPDIPIPNTELFLDHIFSFLFMLIPFFSECWSIIENLREMVEDDLVDFGKIFQGVLEIIRAWRGNG
>NZ_CP019721.1|WP_077707695.1|307974_308367_-|hypothetical-protein
MDKLAIINRIKRSYQSIRIAGIRPTGVLATRALVLVMLVPMILVVAQYALSTIRGYVSPEANQLIDKGVLIIDHINVPSVLMAIVGLCGMFIDKDHNGIPDKLEEPNTLPTNRPGIQQLADDVNHDERGK
>NZ_CP019721.1|WP_077707694.1|307398_307974_-|N-acetylmuramoyl-L-alanine-amidase
MFRQLTMDELKDLALDAYGQIEKAYLHWTGVKGGKHFKDYHINIDRDGTMWTDMEALTNYKEHTYMRNSNAVGIAIEACWDAVSENNLGSEPPTTAQLTTMAQIMAVLTINAGVPLDLQHQMTHAEAADNKDGLDLYYLDPTGFPNNTYGPDSNVDRWDLLVCHEGDERWSGGDWLRGTARWWGAQWGSTI
>NZ_CP019721.1|WP_187658826.1|306857_307484_-|hypothetical-protein
MKVTNDGAGATGYVVLLDGGVLSGVVRFRKEQLCMKLSRTKLYLRLLVSALFLVCLAFLSSVSHAASLEGTSTQEPTISVPVSSWNELKGRLTKAESSINNSEKALQQANDLTAMQGTALTELKIINEERTKELNALKAINEKQGQELTKASNLLTTQEAKLNEASTSLEELTEQIKRNKRTEQRLKRQRDTWAVVSGVFGLAGAIRR
>NZ_CP019721.1|WP_077707693.1|306180_306420_-|hypothetical-protein
MKLKFELDDIMTTQEAAERWNVTADSLKQNCRGRVKNGFKEGEFKKSGKMWLVTRQGMERLYGKESALSSVIKSVSDEH
>NZ_CP019721.1|WP_077707692.1|304861_306028_-|iron-containing-alcohol-dehydrogenase
MYNFDFYNPTHIVFGKDRLDELDTLVPKDAKVLITYGGGSAVHSGLIDHIVKALGNRKVEQFGGIEPNPSLETCERAVAFIKEHGVDFVLAVGGGSVVDATKLIVMGATYDGPVIEVMKAGVPEVPVDMVPNPLPFGTVMTLPATGSEMNNGAVITYGDGKYPVFSSLVFPKFSMLDPTLTFTLPERQVKNGVIDTFVHTTEQYLTYPVEGRIQDRFSEGILKTMIEIGKETVENPENYDIRANHVWASTLALNGLIGAGVPQDWATHLIGHELTAAYHLDHGITLAIVLPALLEVKKADKLEKLAQYATRVWHITEGTNEEKADKAIAKTREFFESLGVSTHLKDYGLGEEAVDKIVKQLEDHGMTQLGENGDVTPEVAREILTRAL
>NZ_CP019721.1|WP_004694895.1|304095_304761_-|AzlC-family-ABC-transporter-permease
MIPMGLSFLFLGVGFGLYATSQGFPWWTAPVLASTIFAGSMEFVTIGLLMAGFDPVNTFMLTLFVNGRHFFYGLSALQRYVHMGWKWFPTVAWMCDESFAINVSTKLPDDVDEKWFYFHVSWLNYIFWVVSTLVGGLFGDLLASVDLRGIGFVLPGLFIVIFLEMLFNAKSNNIRGLGAVGAVVALAMLLLTGKSLFMLASMGCMLVVCYIAYKWGGVHLD
>NZ_CP019721.1|WP_077707691.1|303764_304103_-|branched-chain-amino-acid-transporter-permease
MTSFEIVITVAIVVAGTLLTRFSAFLIFPPGKKAPDFVQYLGKALPAAVMGMLVVYTFKDTIVLSYPYGVPELIALLVTVGMHVWKRNMFMSIGAGTVVYMILVQAVFNIPK
>NZ_CP019721.1|WP_077707690.1|302810_303662_+|aldo/keto-reductase
MEERMDFRILNNGSFIPSIGYGTYKTGTEGETEQAVANALGVGYRLLDTAAYYGNEEAVAKGIKASGIKRTDIIITTKIWHTDAGYDNTMRAVESSLKRLDTNYIDIMLVHQPLGDYYGSWRAMEELYDQNVLRGLGLSNFYEDRLIDLLYHCNVKPVVNQIECHPFNQRQSLLQLMRKHQVVGMAWSPFTRDRQPIFDHPIIKSLAEKYGVSKHQIILRWHIQQGIIPLPKANNVSHMEANFDVFDFKLTNIDMDVMELLDQQDFLEDHHTAPGLERLLQLK
>NZ_CP019721.1|WP_077707689.1|301583_302699_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MQINRFCSVIAILGVMIMALAIAGCGTKTVSVAEVTYKDMPLQIHNDANVTALNKATITPTLTGQVVYAVKVGDQVQQGQTVATVDTSALQQQLASLQGQLAQAQSQSYATAVTTTTAASIDSTQLEQAQRMREAGIITQKEYDRILERSQPQTTTVTTGGGGGVNTAAIEAQIAQVSAQMAASTIVAPIAGTVTSIYNEDRQMAIADRPFMMIQQSTPMVASLSIPRDAAMKLGTAEAKNGMKVLLKVGDQEIPGELTYVDITQPENVPSVLVKATFNNEKGLIKAGEFYTLVIESNVKAKMLTVPTKAVRENQDGKYVYVLTENNTVDVRVVEVGITEGDDVAIISGLNEGDKVIATDGTFELGESVKL
>NZ_CP019721.1|WP_077707698.1|310009_310336_-|hypothetical-protein
MNVKDIDLNIGEDFGIVYAVQDDNVDLTGFKSVFAIRKRASGPLVIKVQGVVSGKIATFNISGKDTLEIKSFGEHVYDAFAYKESEPSRYYKLGMGVVNIIQDVAMHD
>NZ_CP019721.1|WP_077707699.1|310351_311350_-|hypothetical-protein
MEFINIQNKEGVTIINDTYDNLVYLSFPKQKDAVLYTGAMRGITPTVQIPLKPVAYAPMLVPTSKYQYGYIAGEANVIQVFYITNRIYHGDAPLIAVSVPQGFEFAAQWVHKRREQLMVLVVDVIKPGEKVTQAMVDEVKAGIKFYCFGYFEDVMANADTPRIRFVDKVGSSKPNTALQVLGRHKYYKASWATDYNLHNDVIYDSRIRYLRVIDHYVHDWYNQLSNYIPDTFTDMARDPKTYGVKVAIIPMSVIDASVWGPNINNGDKKSHTGRVWQTFRFHDESTVSLKSYQFINWNTVTTYPVGCSGKTTSQYLVVDVTGYDKQGTIPFN
>NZ_CP019721.1|WP_077707700.1|311336_311642_-|hypothetical-protein
MEPHVLAYDANGNIILNLKERLTRIDGRMYVSGIPNRRQQITVNGLQPGQHVWAAAMGQYLVAEVRGNIITYYFAVSQDEYNINRQFKGLTYEGWLAYGIY
>NZ_CP019721.1|WP_077707701.1|311650_315601_-|hypothetical-protein
MVNVIIINNPFKPEQRDTKYLPFKQGKSISYYFSAPGEWVYSVNGHEAAPDTVVNDEDYIVVMPRVEGKSFGILLSIGLAVFTGGIASGAIFGIQSLIWRSVIAMAVGMIGNAIVSKLTAPKVDRSNSEQSNTYGWGGTETVTGQGYPLAVTYGRMKSAGILLSRHVISDGEKQYLNLLYCAGEGELSKIEDISINANPISNYKDVQVDIRKGTNDQTVIPNFNDNFADQSLNYELTESWNTQQVQGNACDAIELTVGFPNGLYYSNDSGGADRTSVTLKAEIRKVGDESWQALPLANQKGMAGHIKRRDAWNFIKSDNNVTNTSDYAGRIEEATNNAFYRVFRFDNLEKARYEIRMRCSAKDGKSLRHINKVYWVQLTQIIYDDFVHPGKALIGIKALATSQLSGTDPKVTWIQERSEVYVFNPYINKYEAQPADNPAWVAYDLIHICRKIGGEYVVFGQPYMRLDYNAFKAWADKCNTNGFTFNYIYDTAMRLWDALKYPEAVGRGKVIPVGTRFTCVSDYQSTPVQLFTVANIKHGSFTEEFQGVEARANSVEISFLNKDKDYERDVIPVYGDTYDESDTLTNPAQVELMGCTSLEQAYKHGKHFLRCNKYEIRTVTIEAFTDAIACTVGDIILIQHDIPEWGEGGRVVAVSGQTITLDKEVSVQPGKNYQLLIRSNSTDIVSTFNVVNVSGLNVIVKEAIPVQPDAVYAFGEISKSAKPFRVLAITKTLSEMTRKIQCMEYYPELYVSDDGTVPSIDYTNHGVSDIQAVGLVSDVYGANGIMYSRIGVTWQLPRDGKVSNVVVNYRNVKSDTWTYIGNYPASTNTTTISDVLLGATYEVRVQAINELGQLTTGVTKSIAIPKMQAPEDVQNLHVLSRYNQTADKSVYYDLQVLFDPPSNPANFDVAEVWYLLKSKSGKPVAGQEWQYAGSSNSQVIIKSLGPGEEYRIKAISVDRFGNRAETAQMVDVIVKPMDAIPAMPSNFGIAFGRNATASWDEVLNADVDYYELRTDNNPGKDTNALLARVKGTSAVLTLSKRADTVYLYARSTLGKYSTAATYEYNVPQLAAPELVVKSQLGGFNLYFSTKPAQAYAIRCHVIGDERTDAFETTSTMLTYSNSAGIYRIRCSFVDVFGDGFVNEKQVVIKTQIDASLLDLESLGLNKVDERIKELDKKFNTNSKETTRRITNLASHTESRITELAGSIDLQVKKSIGEIDGGELVSRINLSQSGVYIAGKLIHITGATKFDDNVIVNRMIQANAVTADKLQVDNLSAVSGTIGLLRSKETGARVEIQDNLITGFDDDNNPRIKLGCW
>NZ_CP019721.1|WP_077707702.1|315604_315931_-|C40-family-peptidase
MHPISDLTDIIGTPFSEMKCWDVVVEVYRRSGIPLPEYTQIQMDEWREVREPMPGSVLVFALYGKNLDHVGVYLGEGKFIHATEHSGTCIEHISKYVPRLKHIYERKE
>NZ_CP019721.1|WP_077707703.1|315914_316520_-|DUF1833-family-protein
MLPLSTASILEKNQISATGVWLMLLEISYKGDTIRLVYNTENIQFQGNTYIAFPFTIQDVTENATDLPNIKLSVSNVTRTIQRMAESNNGFTGANVIIRVVNTNIPGVCEQEEHFVITGTHANAEWMEFTLGTDFSFTRRFPLIRVMKDFCPFKFKGVQCGYKGRETQCNKTLARCRELGNSTRFGGEPTIPQGGLYASNK
>NZ_CP019721.1|WP_077707705.1|316856_320051_-|phage-tail-protein
MANNLIDIVVQLTDKNTEAGLKKITASAEGAKSALGKMKNDLMAIGAGVGVVGIGAKLAKEAIQWDVAVKKLSGITGATAKETSELLAVANYMGVAMEDSAGAFAKFSKNVGAAKEKMEVARAEGKLGTDIFSKLGYTLEDIKGKNTVEVFKMIQERLRGMKDGAEKTRVEMELFGRTGYQMHAMLNMSAEQMDKVAERAKAMGLIIDDETAAKSAKLNRELKDLENTGKRLAVSIGHELVPVFNDYAKGVLDVAKEFESMTAEQKEAIGGIVKFGAEAGAVIVVMRSLTSALGFMRLATIAAAGPWVTLATVAGLAAKNIYDAVYASKTAGSYLNVEVDGMKAHRNLNSDKGTSEAYMANHDGRYWVEDSSFFGFFKNDRLATKEEGARIDAALKQKEEADAAKAKLDEDLAKAKADLANGGLTNTEAINKANEEAAKAAKAQEQAAKKTQQAAEKLTSAVERMSELYRSLTLQSLQIDGSQYEIDKLNAKNQYEANNKNIRDIIRSVSGLSGGVTGEAVSVLDAANEQLGKAYELGADGTWATDCGKLFSDSVLQAFGKDVPRYVPSIMDAARAAGAWHDAGDGYTPKAGDGVVVLGDNHIVISDGAGGYTGANSSTGVVSKPSVSGDFGTITGYVDTSLLAGHTGGAAADTAGSATNAKKLAESDLTASVRAKNEEVYQKRLAEAQRNQTIRVRKMNEDIKKLDFERTGDRLQLLKAEAEAQKAQIDDNVREYTKAVGDKELAEKKAQAERLKLASDTEQKIRELAYTQTSETVDHLTNMVTLGRLSRSDADALLAEELKTYIDYARSEVNEAQLTATQRLQIEKNLLESQQKLWELAGRSLKTSLQEAARQYKQETTNYADLAKSTFDSTMSSINSAWTNNLEAMATGTKSFSKGIRDIFKDMTNAIIKMMIQLTFQQYVMPKLLRLFGGVVNGIGSLGAAKGTSSFAGGSSFSSVFTGNRFAAGGKTNPGLMLVGENGPELLQSSGSHRIYTASETRRLMGGTTSNNVVVNIVNQSGQELESKQQNSRFDGENYVIDVVVRAMESNKGGMRDAIKASAV
>NZ_CP019721.1|WP_077707706.1|320040_320226_-|hypothetical-protein
MRVYNASRMQRRWHSGGIAGFDMPAVLEVAKAYGIEPLPHLIDLLVLLEAKELEVAHKNGQ
>NZ_CP019721.1|WP_004697615.1|320369_320648_-|hypothetical-protein
MAFEDIKLRGLTFAERSELIKAELDPLYTPLPEETPEPAKLLWYRDLAEWIMKNVYKMSDSEIAEAPNDGVMELAIETMRFTNEKKAEIEKN
>NZ_CP019721.1|WP_077707707.1|320659_321622_-|hypothetical-protein
MATAKRAQGSQSHVAIAFEADFGTTPTTGGVITPIISSSVKASQNLNDSTVIRGDRNPAAPFRGNIDTSGSLTVPVGVIDIGYWLKAAFGQPTSNTTGQAPNKKSEHVFKIGNTMPSLTIEQGYPDVNVFQQFAGVRVSKLGFKFGGDAELTASVDVMGCKETLAATTFDAAAKAVNFLPFQNLNATIKEGGVTVANILSCDINFDFGLDGDSYAIGGKGFRTYIDPGIATISGTVKAFFQNKDLLNKAVNGTESSLELRLEQDDWSLTFKLPELVYERQSPGIDGPRGVNIELPFKAYYRADAGKSAAIITLVNNQEQY

Crispr_ID: NZ_CP019721_2

• CRISPR_ID: NZ_CP019721_2
• CRISPR_location: 512612-512734
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP019721_2

Consensus_repeat	Method
CCTATCTCTGAAAATGACTTAGCTCGCTATGGAGG	CRISPRCasFinder

spacers of NZ_CP019721_2

>2.1|512647|53|NZ_CP019721|CRISPRCasFinder
TTATTTTAATAGGTCCTAGTTGGAGATACTAATTTCATATAAAAGGAAAAGCC

CRISPR arrays and Neighbor proteins around NZ_CP019721_2

CRISPR arrays

The CRISPR arrays of NZ_CP019721_2

>merge|NZ_CP019721|2|512612-512734|CRISPRCasFinder
CCTATCTCTGAAAATGACTTAGCTCGCTATGGAGGTTATTTTAATAGGTCCTAGTTGGAGATACTAATTTCATATAAAAGGAAAAGCCCCTATCTCTAAAAATGACTTAGCTCGCTATGGAGG

>NZ_CP019721|2|2|512612-512734|CRISPRCasFinder
CCTATCTCTGAAAATGACTTAGCTCGCTATGGAGG	TTATTTTAATAGGTCCTAGTTGGAGATACTAATTTCATATAAAAGGAAAAGCC
CCTATCTCTAAAAATGACTTAGCTCGCTATGGAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019721.1|WP_008602005.1|513211_513532_-|HigA-family-addiction-module-antidote-protein	unknown	unknown	gnl|CDD|274228
NZ_CP019721.1|WP_077707816.1|503162_504308_-|glycosyl-hydrolase-family-3	unknown	unknown	gnl|CDD|224389
NZ_CP019721.1|WP_038125650.1|506701_507100_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707815.1|501868_503020_-|lactaldehyde-reductase	unknown	unknown	gnl|CDD|182595
NZ_CP019721.1|WP_077707818.1|505205_505832_-|site-2-protease-family-protein	unknown	unknown	gnl|CDD|100079
NZ_CP019721.1|WP_077707819.1|505841_506612_-|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl|CDD|223672
NZ_CP019721.1|WP_077707820.1|507254_507773_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP019721.1|WP_077707829.1|519277_519853_-|TonB-dependent-receptor	unknown	unknown	unknown
NZ_CP019721.1|WP_077707832.1|521989_523246_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707822.1|511585_512359_-|hypothetical-protein	unknown	unknown	gnl|CDD|319844
NZ_CP019721.1|WP_077707821.1|508029_508620_+|nitroreductase	unknown	unknown	gnl|CDD|380313
NZ_CP019721.1|WP_077707824.1|513934_514651_-|DUF554-domain-containing-protein	unknown	unknown	gnl|CDD|377371
NZ_CP019721.1|WP_173014537.1|515701_516145_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707828.1|518291_518828_-|flavin-reductase	unknown	unknown	gnl|CDD|224766
NZ_CP019721.1|WP_077707827.1|516754_518086_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707830.1|519910_521167_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707825.1|515102_515702_-|DNA-3-methyladenine-glycosylase-I	unknown	unknown	gnl|CDD|377025
NZ_CP019721.1|WP_004694513.1|510154_511477_+|MFS-transporter	unknown	unknown	gnl|CDD|236889
NZ_CP019721.1|WP_077707817.1|504592_504826_-|(2Fe-2S)-binding-protein	unknown	unknown	gnl|CDD|377304
NZ_CP019721.1|WP_077707823.1|512771_513125_-|Spx/MgsR-family-RNA-polymerase-binding-regulatory-protein	unknown	unknown	gnl|CDD|239334

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP019721.1|WP_077707816.1|503162_504308_-|glycosyl-hydrolase-family-3	gnl|CDD|224389	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism].	2.90858e-75
NZ_CP019721.1|WP_004694513.1|510154_511477_+|MFS-transporter	gnl|CDD|236889	PRK11273, glpT, glycerol-3-phosphate transporter.	0
NZ_CP019721.1|WP_077707815.1|501868_503020_-|lactaldehyde-reductase	gnl|CDD|182595	PRK10624, PRK10624, L-1,2-propanediol oxidoreductase; Provisional.	0
NZ_CP019721.1|WP_077707820.1|507254_507773_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	5.39159e-21
NZ_CP019721.1|WP_077707819.1|505841_506612_-|carboxymuconolactone-decarboxylase-family-protein	gnl|CDD|223672	COG0599, COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown].	2.4926e-11
NZ_CP019721.1|WP_008602005.1|513211_513532_-|HigA-family-addiction-module-antidote-protein	gnl|CDD|274228	TIGR02607, Virulence-associated_protein_I, addiction module antidote protein, HigA family. Members of this family form a distinct clade within the larger family HTH_3 of helix-turn-helix proteins, described by pfam01381. Members of this clade are strictly bacterial and nearly always shorter than 110 amino acids. This family includes the characterized member HigA, without which the killer protein HigB cannot be cloned. The hig (host inhibition of growth) system is noted to be unusual in that killer protein is uncoded by the upstream member of the gene pair. [Regulatory functions, DNA interactions, Regulatory functions, Protein interactions, Mobile and extrachromosomal element functions, Other].	4.70932e-29
NZ_CP019721.1|WP_077707822.1|511585_512359_-|hypothetical-protein	gnl|CDD|319844	cd07544, P-type_ATPase_HM, P-type heavy metal-transporting ATPase; uncharacterized subfamily. Uncharacterized subfamily of the heavy metal-transporting ATPases (Type IB ATPases) which transport heavy metal ions (Cu(+), Cu(2+), Zn(2+), Cd(2+), Co(2+), etc.) across biological membranes. The characteristic N-terminal heavy metal associated (HMA) domain of this group is essential for the binding of metal ions. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0.00611407
NZ_CP019721.1|WP_077707821.1|508029_508620_+|nitroreductase	gnl|CDD|380313	cd02136, PnbA_NfnB-like, nitroreductase similar to Mycobacterium smegmatis NfnB. Members of this family utilize FMN as a cofactor and catalyze reduction of a variety of nitroaromatic compounds, including nitrofurans, nitrobenzens, nitrophenol, nitrobenzoate and quinones by using either NADH or NADPH as a source of reducing equivalents in an obligatory two-election transfer mechanism. The enzyme is typically a homodimer. Mycobacterium smegmatis nitroreductase NfnB plays a role in resistance to benzothiazinone.	1.47848e-43
NZ_CP019721.1|WP_077707824.1|513934_514651_-|DUF554-domain-containing-protein	gnl|CDD|377371	pfam04474, DUF554, Protein of unknown function (DUF554). Family of uncharacterized prokaryotic proteins. Multiple predicted transmembrane regions suggest that the region is membrane associated.	1.35108e-68
NZ_CP019721.1|WP_077707828.1|518291_518828_-|flavin-reductase	gnl|CDD|224766	COG1853, COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only].	2.70772e-14
NZ_CP019721.1|WP_077707825.1|515102_515702_-|DNA-3-methyladenine-glycosylase-I	gnl|CDD|377025	pfam03352, Adenine_glyco, Methyladenine glycosylase. The DNA-3-methyladenine glycosylase I is constitutively expressed and is specific for the alkylated 3-methyladenine DNA.	4.89063e-108
NZ_CP019721.1|WP_077707817.1|504592_504826_-|(2Fe-2S)-binding-protein	gnl|CDD|377304	pfam04324, Fer2_BFD, BFD-like [2Fe-2S] binding domain. The two Fe ions are each coordinated by two conserved cysteine residues. This domain occurs alone in small proteins such as Bacterioferritin-associated ferredoxin (BFD). The function of BFD is not known, but it may may be a general redox and/or regulatory component involved in the iron storage or mobilisation functions of bacterioferritin in bacteria. This domain is also found in nitrate reductase proteins in association with Nitrite and sulphite reductase 4Fe-4S domain (pfam01077), Nitrite/Sulfite reductase ferredoxin-like half domain (pfam03460) and Pyridine nucleotide-disulphide oxidoreductase (pfam00070). It is also found in NifU nitrogen fixation proteins, in association with NifU-like N terminal domain (pfam01592) and NifU-like domain (pfam01106).	1.69055e-13
NZ_CP019721.1|WP_077707823.1|512771_513125_-|Spx/MgsR-family-RNA-polymerase-binding-regulatory-protein	gnl|CDD|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	4.8139e-57
NZ_CP019721.1|WP_077707818.1|505205_505832_-|site-2-protease-family-protein	gnl|CDD|100079	cd06158, S2P-M50_like_1, Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the S2P/M50 family of RIP proteases use proteolytic activity within the membrane to transfer information across membranes to integrate gene expression with physiologic stresses occurring in another cellular compartment. In eukaryotic cells they regulate such processes as sterol and lipid metabolism, and endoplasmic reticulum stress responses. In prokaryotes they regulate such processes as sporulation, cell division, stress response, and cell differentiation. This group includes bacterial, eukaryotic, and Archaeal S2P/M50s homologs with a minimal core protein and no PDZ domains.	2.38277e-40

Protein sequences

>NZ_CP019721.1|WP_077707822.1|511585_512359_-|hypothetical-protein
MKFLQSLSAQVSLRTQGAILALGLLFIILDALTEPMNPAIDLAWVTVIICGLPLLINSVQSILDHLEIHANFLIVIAMVALIAIGDYHTAAYVGLIVHGGFFLEQLITGDVHYTLDDDMLPTMPTQLVALRQGINNYSSVIVVAVMLLSMGSYALTQNFMHTITLLVILCPCSLELVLVALMMGSLVDENSPTAGLSKEAKQCHLGLLIVSIMFHVAIIGAGVLGSINPVTAAALHGLARLGLVYNLKVLNGSLCVA
>NZ_CP019721.1|WP_004694513.1|510154_511477_+|MFS-transporter
MSIFSPAPHIERLPEAQIDSTYKRLRREVFAGTFIGYATFYLIRQNFSLAVPYMIAEYGYTKADLGIVMTILSVAYGVSKFVMGNASDRSNPKYFSTVGLLLSALVMLLFGTLPGVMSSIPIMCVLALLNGWFQGMGYPPYAKNMVTWFSRSERGAWWSWWNVSHNLGGGIIAPLATLGIYLFGTWHSIFFFPALISIVLAIITFVLLKDTPQSCGLPPIEEYKHEVVHTHTENEEKSTFKEIFYKYILHNKYLWYLAIANIFVYFIRYGVVSWAPTYLTAVKGFTKEGSRWAYFLYEWAGIPGMLVSGYLSDRVFRGRRAPATICFMLFVILAILVYWFNPAGNILIDNLALIAIGFLIYGPVMMIGLQAADMVPRVATGGATGLTGLLGYLIGSAGAGAFMGLMVDLYGWDGGFIALVGACILSIVFLLLTLGDKGQQ
>NZ_CP019721.1|WP_077707821.1|508029_508620_+|nitroreductase
MNTLGCIKTRHSTRKFKADQLSRKLIDQVLDAGRRAPSGGNTQLTHFMVITNQDVLNELVTLVQEEYGKMPITENTLPYMVNIIKMSAEGKFVFNYGAPVLIVLASKPSYANNFADVSCAMQNMMLACNELDLGSCWVNQIRHLQDNERIQAKMHELGLSEDEKVYASLAIGYPDMPNGLNRREIEAKGYPVTYID
>NZ_CP019721.1|WP_077707820.1|507254_507773_-|MarR-family-transcriptional-regulator
MAEIGVLEGYKHKEDVPDSEYLRLENQLSFPLYVVAKEIVNAYRSHLDPLNLTYTQYVVMMALWQYGDLSVKELGQVLRLDSGTLTPLLKKLEAKAFLKRKRSRQDERVVMVTLTDTGKALRDVAVHIPRRLAESSGPIFDVEETRQLRMLLNKLLEAIDNANAKTAENMKG
>NZ_CP019721.1|WP_038125650.1|506701_507100_-|hypothetical-protein
MNKNLLGAFVLAGTLLVGGVANAANWNGLANYPEVPNSANGTETYFFDKASEFKGIDSSRNNVFGVNVINMHNNQYGEATLFKYLVNPSLHTVYRYAPDGQVYQIQPGTNEFNMFMAAWKEVYGTTFEFPAL
>NZ_CP019721.1|WP_077707819.1|505841_506612_-|carboxymuconolactone-decarboxylase-family-protein
MSKSEFAQAYTERMFPDIAAPAGYIDPEFEVLFDNFAFDEVITEEDRNVPAKDRFLAILATLVGASAVDEYALMLPAALNFGLIPDEVVELIYQAVPYLGIGRVRPFFKVTNKIFDYRGEAIVDPSRSTITGESRLEKGVEKQVEIFGESMRNSYQEGPEDIRHINKWLANMFGDYYTRKGLSVAHREMITFCFLAAQGGCEAQLKAHVEGNLNVGNSKQYLINIASQCVPYIGYPRTLNALRCIQEGYTAWEAKQ
>NZ_CP019721.1|WP_077707818.1|505205_505832_-|site-2-protease-family-protein
MFDLNPVQILASIPAIMIVFSIFGYAEAKVATWFGDPTPRLAGRLTLSPMAHLDLIGTICIILVGFGWAKPMSINPSYFQDPRRDISLLAFAGPVAGLIAGFIFTFIYMLLGKLGLMESQGLAMVMQYIILYSIGLSIFCLIPFPPLPGFNIILPWLPTEWQMRYYQLGMLNLLFFIILINTPIISIVIRPLQQTIFKIYFAIIGLIL
>NZ_CP019721.1|WP_077707817.1|504592_504826_-|(2Fe-2S)-binding-protein
MNFEENQVPEAILDKLTKVCTCRSITRKTIKEAILNGAHTFPQVKEATRAGTGACGGKGCGPRIVKLLAEMKEQGKI
>NZ_CP019721.1|WP_077707816.1|503162_504308_-|glycosyl-hydrolase-family-3
MFRRFIAVTMIGALALTTGCGLHNPFTSKAEPVTYESVAQSELSPEQKVDKLVANMSDADKVGQLLMIGIHGTTLNDDAKFMLNEYRVGGIILFDRNMESKDQVKTLIADINKAGKSVGLTPLFLGIDQEGGAVARMDDKLIKVPPAEELGKTSVEQAVSLAKQSGVELKDLGFNINFAPVADLGLTYGRSFSTNPDEVVRYAGAVGKAYDEAGLWYSYKHFPGIGKTDVDLHADTSIVPVSKETLLSEDTKVFIDLIKQSKPNTYTIMVSHAMYPQIDPDHPASLSKAIITDWLRKDIGYNGVVVTDDMDMGALAKHYTFGDMAVQSILAGSDILLVCHEYEHMQEAYNGLMKAVKDGRISKERLDESVKRILLMKMSKI
>NZ_CP019721.1|WP_077707815.1|501868_503020_-|lactaldehyde-reductase
MARRIMLNGTSYFGQGAIQEIVNEIKNRHFKKVLVTSTPDLFEFKVATKVTDLLDAAGIAYEVYDGIKPNPTIENVTAGVEACKAAGADVIVAVGGGSPIDTSKAIATIITNPEFADVRSLEGLAPTKNPCLPIIAVTTTSGTAAEVTINYVITDVEKNRKFVCVDPHDIPIVAIVDPDMSASMPTGLCAATGMDALVHAVEGYITKGAWELTDMLHLKAIEIIGRSLRSAVAGDYAGREAMSLGQYIAGMGFSNVGLGIVHSMAHPLSAVYDIPHGKACAMLLTAVLKFNAPATGEKYREIARVMGVPHVDTMDESTYRQAAIDVIQKLADDVGIPKSLSEAGVKREDISFLAESAFNDACTPGNPRDASLEEIIGIYESIF
>NZ_CP019721.1|WP_077707823.1|512771_513125_-|Spx/MgsR-family-RNA-polymerase-binding-regulatory-protein
MLFVEYPKCTTCKKAKKFLDDHNIKYTDRDIKSENPTAEEIAAWYPQSGKDLKAFFNTSGMIYREQQLKDKLPNLSEEEKLALLASNGMLVKRPILVLEDKVLVGFKEAEWVEALKL
>NZ_CP019721.1|WP_008602005.1|513211_513532_-|HigA-family-addiction-module-antidote-protein
MEKFIPTPTISEILKEEFMDPLGLSAYRLAKDIHVPVSRIQEILNGTRSISADTSLRLAKYFGVSEGYFLRLQMDVDLRTAKLSEGMDEVLSSIAHCASLEPVDCQ
>NZ_CP019721.1|WP_077707824.1|513934_514651_-|DUF554-domain-containing-protein
MIGLGTAINIGLIIAGSLCGLAFGRFMKENLKQTLMIVSGIIVLLLGMSGAMQYMLVIVNGSLQTTGPLLMIISMVVGAVIGEIIDLNHWITVFGDWVKARTGNAGDPKFTHAFITASLTFTVGAMGVLGSIQDGLTGNYQTLLLKGILDGIIVMVMVSSMGKGALFSFIPVGITQWLITAMAHIAAPLMTPSAIDNLSYVGSILIFCVGIDLIWPGKIRIANLLPAIFVAMGLTFLL
>NZ_CP019721.1|WP_077707825.1|515102_515702_-|DNA-3-methyladenine-glycosylase-I
MTTCEWPTTPLYQDYHDYEWGRPIHDDQHQFEHLCLESLQCGLSWLTILNKRNIIRACFDHFDIDAVAAYGESDIERIMQTVGMLKHRPKIEAIINNAAAFKRIQSEFGSFCNYIWGFTNHKTIIYENHPEGHFPTKNGLSTRISKDLKQRGFKFVGPVTIYSHLQASGLINDHGKDCPCFEEINKTADIVWLPVDDEA
>NZ_CP019721.1|WP_173014537.1|515701_516145_-|hypothetical-protein
MSVVKPLLWLLEPYIVYKAYLWGARFMAQPFTWEGELDWFAFMLTLLLVIDVVALPLVIFYCPGLNPGVRVPDWIRRLGMPIYTVHNWLDSKVGGDTSTPIIWLRKALHSLLLFIYYLVSFYVGGHLIMGLVVALMYDVLVWAHGGV
>NZ_CP019721.1|WP_077707827.1|516754_518086_+|hypothetical-protein
MTKLPLLACAFIMSTILSPIGAIDVNIPGADSKFSKDAYINYQTTNPDIEKDVANYVKTLKLTDKANGINKNEIEYTKAASIYRGQNYHNTVISVHDQYNQIRLSFPVAGIKSDYHIGRYQNPSRTIEDYRVLTNNGSLNLEIDYADFKDYDWRNTKIAYEKLTDKDVRNFLQDNAKRKSSKQISDIKGTVFSYPTVTYSTWDSMKMPHFKNGKKTTLTIDTINFKFKGYNMRHPLYHAGFVYYDNNPVLNKVPTDKLLANYVLPSVQNLNELNQYSRIESLNGVQYRVPKDAIYEGESKGSEHQDIRYYKKGDIIFFVSTNNIPKNPYARDLVVNGHYNFKINLDTFWDIYYSQPTSDYINYAVIWNNNIPGLSTHIYTPHKDNHILTFNSYDGTYSFTYIIFYPSFLHAEEVQKLRNMIEFFDSTNNPSFKMQEHVLFPEA
>NZ_CP019721.1|WP_077707828.1|518291_518828_-|flavin-reductase
MKPFETKDYKAFTMFENHWALVTAGTLDNFNTCTVSWGSMGNIWGPNGGDISTVTVYIHPARYTQEFMAKYDTFTVSFFPESYRKALGYLGSHSGRDENKVANSGLTPVAVGDGVTFKEAELTFVCKKLYEHQFDEAHLAEKVKDYYASNPAVYTQTGHDRWEPHYMYIGEVVDAIED
>NZ_CP019721.1|WP_077707829.1|519277_519853_-|TonB-dependent-receptor
MKRKYLITGLVIGLQLVSGYSYESDASWLSKTWDRLETNAAKQSYDWPKAEQYTHYAGGQIVGTTLPDEDMMILGVSLGNTFDSVKASLGQPTKETSRGLTYGGVTFGNFKMDGVGPIVTYMMIENRDATTHRGIAVGDSMRKVLNVYGRPDLVDSNNRWFYGKYRYRTDMMHGIQFEQKGDKVSKILIYK
>NZ_CP019721.1|WP_077707830.1|519910_521167_-|hypothetical-protein
MLRKSLIMMALATAFTMNVNAVQIKVPEGQPPVPGADASIPANAYENYSHINEKAIQEAEAFSAKVQKTVEKPSIAIEKVFKEKSGLAKAVKLGEYSQSTVILLHDEKNNIRLAVPNISLRGDTVESKSSDGPLFVVRGFTSILMVGPPHGKEFSKRMHNEGVYTYSGLENASWKILKAKTHVMYTEFTPKNTNTTYGITYLGGGDVKEPYQDKIAEVVMSNYIIPSIESLSRLDNYSHVKHWDNFSYRIPKKAKLVSEVMEDNKYEVRTYEDAGIKIRVLRFQIDPNVVDKSLAKKQIFAFLNKYGDLEAPTQYATVWNNGLPGFLVDRYKSNGGSYLRHFTKDSEYYYSYRIDYDESKSSYKHKQLRDMVEYVDFDNVESLRKAPQWRISDSHKKKLDADPIFNPWYMEWIKILTQ
>NZ_CP019721.1|WP_077707832.1|521989_523246_-|hypothetical-protein
MLRKSVMMMALAVTFTMNVSAIQIEVPAGQPAMPGSDASIPANAYENYRHVNEVAEQNAESYSEFIKSQPMNPKSGMDKLYRERPGLAKALELADYSQSTVVLIHEGNKNIRLSVPNVSFRGDTVESKSGKGPLYAVRSLSSFLVVGPPHGKELNKYAEEEGKYTYPGLHDTSWKLMSNNARVMYTEFTPNDSKTTYGITYGGWVNTEDPYQDKSPEVVMSNYIIPSIESLSGLDTYSRVEHWGNFSYRVPKTAKLVSETVENSQYDVRTYEDTGSKIRVVRTSILGEKRDGTVIKSSILSFLRKYNDLETPTQYAVVWNNGIAGSLIDSYKPNGESYLRHVVKDSVYFYSYRINYDESKTSYTHKQWRDMIEYVGFDDAVKLRKGPQWREDGTYKEKLESGPIFIPWYMEWVKLLNQ

Crispr_ID: NZ_CP019721_3

• CRISPR_ID: NZ_CP019721_3
• CRISPR_location: 531403-532136
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 9 spacers
• Cas_protein_info: cas6,csm3gr7,csx19,csx10gr5

Consensus repeat of NZ_CP019721_3

Consensus_repeat	Method
GTTTCCGTCCCCATNAGGGGATTATTTAATTTAAC	CRT
GGGGATTATTTAATTTAAC	PILER-CR

spacers of NZ_CP019721_3

>3.1|531438|45|NZ_CP019721|CRT
CAGCGCCAACCATCAACAAATACCGATAGACCTTAAAGGGTACTT
>3.2|531518|42|NZ_CP019721|CRT
GCCATACCGCAGCATGAATAATGCAGCACGTATTAATGTAGG
>3.3|531595|42|NZ_CP019721|CRT
TAAATGTCCCTGTTGATGTATTAAGACCTCAAACAATAGCTT
>3.4|531672|41|NZ_CP019721|CRT
TAATCAAGCACGTAATTACGTACCAAACCTAACGTAATTAT
>3.5|531748|43|NZ_CP019721|CRT
CTCACCAACGGCTTTGAAAAAATGCTATTCATGACGCTTGACG
>3.6|531826|43|NZ_CP019721|CRT
GCTTATATAATGGCAAGACCTAAAGCGAAAGGGGTTGAGTATT
>3.7|531904|44|NZ_CP019721|CRT
TATTTAACGCCTAAAACCTTATTCGCACCTAGCCACTTTGATAC
>3.8|531983|41|NZ_CP019721|CRT
GAAACTGCAGATTTAATTATTACGCCAGTTTCACTTAGTCA
>3.9|532059|43|NZ_CP019721|CRT
ATAATGATAAGTATATATCGTTTTGATGAGTTTATAATTTATT
>3.10|531438|61|NZ_CP019721|PILER-CR
CAGCGCCAACCATCAACAAATACCGATAGACCTTAAAGGGTACTTGTTTCCGTCCCCATTA
>3.11|531518|58|NZ_CP019721|PILER-CR
GCCATACCGCAGCATGAATAATGCAGCACGTATTAATGTAGGGTTTCCGTCCCCATTA
>3.12|531595|58|NZ_CP019721|PILER-CR
TAAATGTCCCTGTTGATGTATTAAGACCTCAAACAATAGCTTGTTTCCGTCCCCATTA
>3.13|531672|57|NZ_CP019721|PILER-CR
TAATCAAGCACGTAATTACGTACCAAACCTAACGTAATTATGTTTCCGTCCCCATCA
>3.14|531748|59|NZ_CP019721|PILER-CR
CTCACCAACGGCTTTGAAAAAATGCTATTCATGACGCTTGACGGTTTCCATCCCCTAAT
>3.15|531826|59|NZ_CP019721|PILER-CR
GCTTATATAATGGCAAGACCTAAAGCGAAAGGGGTTGAGTATTGTTTCCGTCCCCTAAT
>3.16|531904|60|NZ_CP019721|PILER-CR
TATTTAACGCCTAAAACCTTATTCGCACCTAGCCACTTTGATACGCTTCCGTCCCCATCA
>3.17|531983|57|NZ_CP019721|PILER-CR
GAAACTGCAGATTTAATTATTACGCCAGTTTCACTTAGTCAGTTTCCGTCCCCATCA
>3.18|532059|59|NZ_CP019721|PILER-CR
ATAATGATAAGTATATATCGTTTTGATGAGTTTATAATTTATTGTTTCCGTCCCCATCA

CRISPR arrays and Neighbor proteins around NZ_CP019721_3

CRISPR arrays

The CRISPR arrays of NZ_CP019721_3

>merge|NZ_CP019721|3|531403-532136|CRT,PILER-CR
CTTTTCTGACCCCATTGGGGATTATTTAATTTAACCAGCGCCAACCATCAACAAATACCGATAGACCTTAAAGGGTACTTGTTTCCGTCCCCATTAGGGGATTATTTAATTTAACGCCATACCGCAGCATGAATAATGCAGCACGTATTAATGTAGGGTTTCCGTCCCCATTAGGGGATTATTTAATTTAACTAAATGTCCCTGTTGATGTATTAAGACCTCAAACAATAGCTTGTTTCCGTCCCCATTAGGGGATTATTTAATTTAACTAATCAAGCACGTAATTACGTACCAAACCTAACGTAATTATGTTTCCGTCCCCATCAGGGGATCATTTAATTTAACCTCACCAACGGCTTTGAAAAAATGCTATTCATGACGCTTGACGGTTTCCATCCCCTAATGGGGATTATTTAATTTAACGCTTATATAATGGCAAGACCTAAAGCGAAAGGGGTTGAGTATTGTTTCCGTCCCCTAATGAGGATTGTTTAATTTAACTATTTAACGCCTAAAACCTTATTCGCACCTAGCCACTTTGATACGCTTCCGTCCCCATCAGGGGATTATTTAATTTAACGAAACTGCAGATTTAATTATTACGCCAGTTTCACTTAGTCAGTTTCCGTCCCCATCAGGGGATTATTTAATTTAACATAATGATAAGTATATATCGTTTTGATGAGTTTATAATTTATTGTTTCCGTCCCCATCAGGGGATTATTTAATTTAAC

>NZ_CP019721|3|1|531403-532136|CRT
CTTTTCTGACCCCATTGGGGATTATTTAATTTAAC	CAGCGCCAACCATCAACAAATACCGATAGACCTTAAAGGGTACTT
GTTTCCGTCCCCATTAGGGGATTATTTAATTTAAC	GCCATACCGCAGCATGAATAATGCAGCACGTATTAATGTAGG
GTTTCCGTCCCCATTAGGGGATTATTTAATTTAAC	TAAATGTCCCTGTTGATGTATTAAGACCTCAAACAATAGCTT
GTTTCCGTCCCCATTAGGGGATTATTTAATTTAAC	TAATCAAGCACGTAATTACGTACCAAACCTAACGTAATTAT
GTTTCCGTCCCCATCAGGGGATCATTTAATTTAAC	CTCACCAACGGCTTTGAAAAAATGCTATTCATGACGCTTGACG
GTTTCCATCCCCTAATGGGGATTATTTAATTTAAC	GCTTATATAATGGCAAGACCTAAAGCGAAAGGGGTTGAGTATT
GTTTCCGTCCCCTAATGAGGATTGTTTAATTTAAC	TATTTAACGCCTAAAACCTTATTCGCACCTAGCCACTTTGATAC
GCTTCCGTCCCCATCAGGGGATTATTTAATTTAAC	GAAACTGCAGATTTAATTATTACGCCAGTTTCACTTAGTCA
GTTTCCGTCCCCATCAGGGGATTATTTAATTTAAC	ATAATGATAAGTATATATCGTTTTGATGAGTTTATAATTTATT
GTTTCCGTCCCCATCAGGGGATTATTTAATTTAAC

>NZ_CP019721|3|1|531419-532136|PILER-CR
GGGGATTATTTAATTTAAC	CAGCGCCAACCATCAACAAATACCGATAGACCTTAAAGGGTACTTGTTTCCGTCCCCATTA
GGGGATTATTTAATTTAAC	GCCATACCGCAGCATGAATAATGCAGCACGTATTAATGTAGGGTTTCCGTCCCCATTA
GGGGATTATTTAATTTAAC	TAAATGTCCCTGTTGATGTATTAAGACCTCAAACAATAGCTTGTTTCCGTCCCCATTA
GGGGATTATTTAATTTAAC	TAATCAAGCACGTAATTACGTACCAAACCTAACGTAATTATGTTTCCGTCCCCATCA
GGGGATCATTTAATTTAAC	CTCACCAACGGCTTTGAAAAAATGCTATTCATGACGCTTGACGGTTTCCATCCCCTAAT
GGGGATTATTTAATTTAAC	GCTTATATAATGGCAAGACCTAAAGCGAAAGGGGTTGAGTATTGTTTCCGTCCCCTAAT
GAGGATTGTTTAATTTAAC	TATTTAACGCCTAAAACCTTATTCGCACCTAGCCACTTTGATACGCTTCCGTCCCCATCA
GGGGATTATTTAATTTAAC	GAAACTGCAGATTTAATTATTACGCCAGTTTCACTTAGTCAGTTTCCGTCCCCATCA
GGGGATTATTTAATTTAAC	ATAATGATAAGTATATATCGTTTTGATGAGTTTATAATTTATTGTTTCCGTCCCCATCA
GGGGATTATTTAATTTAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019721.1|WP_077707840.1|537606_538281_-|phosphoribosyltransferase	unknown	unknown	gnl|CDD|223970
NZ_CP019721.1|WP_077707841.1|538619_539423_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	gnl|CDD|227838
NZ_CP019721.1|WP_077708640.1|536657_537653_-|DNA-processing-protein-DprA	unknown	unknown	gnl|CDD|376794
NZ_CP019721.1|WP_077707834.1|524423_525005_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_187658828.1|531180_531345_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707839.1|536094_536631_-|hydrolase	unknown	unknown	unknown
NZ_CP019721.1|WP_077707829.1|519277_519853_-|TonB-dependent-receptor	unknown	unknown	unknown
NZ_CP019721.1|WP_077707832.1|521989_523246_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707833.1|523845_524415_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707846.1|544905_545553_-|CRISPR-associated-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|377130
NZ_CP019721.1|WP_077707842.1|539422_541432_-|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|274902
NZ_CP019721.1|WP_077707828.1|518291_518828_-|flavin-reductase	unknown	unknown	gnl|CDD|224766
NZ_CP019721.1|WP_077707843.1|541433_541997_-|TIGR03984-family-CRISPR-associated-protein	csx19	cls001376_csx19_CAS-III-D	gnl|CDD|274900
NZ_CP019721.1|WP_077707845.1|543337_544918_-|hypothetical-protein	csx10gr5	cls000715_csx10gr5_CAS-III-D	unknown
NZ_CP019721.1|WP_077707830.1|519910_521167_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707838.1|533722_535978_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707836.1|527040_529434_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707844.1|541989_543324_-|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl|CDD|187857
NZ_CP019721.1|WP_077707835.1|525278_526697_+|sodium:solute-symporter-family-protein	unknown	unknown	gnl|CDD|271357
NZ_CP019721.1|WP_077707837.1|529870_531175_+|cytosine-permease	unknown	unknown	gnl|CDD|236821

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP019721.1|WP_077707841.1|538619_539423_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	3.3e-15	51.5	0.0
NZ_CP019721.1|WP_077707842.1|539422_541432_-|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	1.7e-156	517.6	0.7
NZ_CP019721.1|WP_077707845.1|543337_544918_-|hypothetical-protein	csx10gr5	cls000715_csx10gr5_CAS-III-D	9.6e-13	42.7	0.8
NZ_CP019721.1|WP_077707843.1|541433_541997_-|TIGR03984-family-CRISPR-associated-protein	csx19	cls001376_csx19_CAS-III-D	1.4e-49	163.0	0.2
NZ_CP019721.1|WP_077707844.1|541989_543324_-|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	1.6e-34	114.6	0.0
NZ_CP019721.1|WP_077707846.1|544905_545553_-|CRISPR-associated-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	9.6e-38	124.4	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP019721.1|WP_077707841.1|538619_539423_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl|CDD|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.40482e-05
NZ_CP019721.1|WP_077707842.1|539422_541432_-|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl|CDD|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	8.61432e-150
NZ_CP019721.1|WP_077708640.1|536657_537653_-|DNA-processing-protein-DprA	gnl|CDD|376794	pfam02481, DNA_processg_A, DNA recombination-mediator protein A. The SMF family, of DNA processing chain A, dprA, are a group of bacterial proteins. In H. pylori, dprA is required for natural chromosomal and plasmid transformation. It has now been shown that DprA is found to bind cooperatively to single-stranded DNA (ssDNA) and to interact with RecA. In the process, DprA-RecA-ssDNA filaments are produced and these filaments catalyze the homology-dependent formation of joint molecules. While the E.coli SSB protein limits access of RecA to ssDNA, DprA alleviates this barrier. It is proposed that DprA is a new member of the recombination-mediator protein family, dedicated to natural bacterial transformation.	7.7447e-41
NZ_CP019721.1|WP_077707843.1|541433_541997_-|TIGR03984-family-CRISPR-associated-protein	gnl|CDD|274900	TIGR03984, hypothetical_protein_FrEUN1fDRAFT_5778, CRISPR-associated protein, TIGR03984 family. Members of this protein family are found exclusively in CRISPR-containing organisms, in operon contexts with RAMP (repeat-associated mystery protein) proteins also linked to CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats).	4.04648e-46
NZ_CP019721.1|WP_077707828.1|518291_518828_-|flavin-reductase	gnl|CDD|224766	COG1853, COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only].	2.70772e-14
NZ_CP019721.1|WP_077707844.1|541989_543324_-|CRISPR-associated-protein	gnl|CDD|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	2.90366e-15
NZ_CP019721.1|WP_077707840.1|537606_538281_-|phosphoribosyltransferase	gnl|CDD|223970	COG1040, ComFC, Predicted amidophosphoribosyltransferases [General function prediction only].	0.00821492
NZ_CP019721.1|WP_077707846.1|544905_545553_-|CRISPR-associated-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.49345e-12
NZ_CP019721.1|WP_077707835.1|525278_526697_+|sodium:solute-symporter-family-protein	gnl|CDD|271357	cd10322, SLC5sbd, Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain. This family represents the solute-binding domain of SLC5 proteins (also called the sodium/glucose cotransporter family or solute sodium symporter family) that co-transport Na+ with sugars, amino acids, inorganic ions or vitamins. Family members include: the human glucose (SGLT1, 2, 4, 5), chiro-inositol (SGLT5), myo-inositol (SMIT), choline (CHT), iodide (NIS), multivitamin (SMVT), and monocarboxylate (SMCT) cotransporters, as well as Vibrio parahaemolyticus glucose/galactose (vSGLT), and Escherichia coli proline (PutP) and pantothenate (PutF) cotransporters. Vibrio parahaemolyticus Na(+)/galactose cotransporter (vSGLT) has 13 transmembrane helices (TMs): TM-1, an inverted topology repeat: TMs1-5 and TMs6-10, and TMs 11-12 (TMs numbered to conform to the solute carrier 6 family Aquifex aeolicus LeuT). One member of this family, human SGLT3, has been characterized as a glucose sensor and not a transporter. Members of this family are important in human physiology and disease.	3.8582e-92
NZ_CP019721.1|WP_077707837.1|529870_531175_+|cytosine-permease	gnl|CDD|236821	PRK11017, codB, cytosine permease; Provisional.	1.42691e-79

Protein sequences

>NZ_CP019721.1|WP_187658828.1|531180_531345_+|hypothetical-protein
MAIHKLSAILGTIIMGIGSFITCLATSESTITLGNGMLVVSIIMMGFGYSKWQP
>NZ_CP019721.1|WP_077707837.1|529870_531175_+|cytosine-permease
MSKEKLEFVEPVNTNTDNEYSREPVPLGSRKSCFSLTIVWTGFVFLVTSMMAGGGLAAGLTFNELLLAMVLGNIFLCIIAGLVSVIAYKTGLTFALLTRYSFGQEGSRIASLFVPIVNLGWYTIQAALYGHFIAQVFNLSYIGEIIAMMLSAVIMGIFAVLGIKSLAVFGYIAIPSIVFLSLGTAARSVQTIGGWQELFNYVPLQSIDLLSGITIVIGTWILSTATCIADIMRYGKSKKDVITASTIGLLGGNTLMISCGAIAGVAMNDGDLINVLLSFGLVFPSLLLLTTNIFTTNGANLYSTSLNLANSFKLNRNIMLAVLIAISALATMTQPYKIDSLFVFLSTLGIIVPPLCGIILADFYLVHRGKYIDYNKATFKKWNLVPWITWAIALVCVKFIPFGLASLNGIVIGALLYALITYIVKPNVVSKSKG
>NZ_CP019721.1|WP_077707836.1|527040_529434_-|hypothetical-protein
MYNVTITTTGIFDEIRPSLFPPIEGKEGITFMNALVYRVDPKSSFEEGDAITDNDPEFALERERIRAFVAALCEAYGKPYGELRDEFVEALPEFMLYGTYKGQALLSTGRNGYYQVFPMYKSNRGRRLLFQDGYAPNQITKYICDHMLRYFVITLFSNIGAFGSDAGVQHIATPLSLYGLHQALDDVDRAYLSELITVNSLDNTYSMDASNQSEFLLLADALGAYMVQAMDGYTESERLDSLSQDPFFRKICEPVHRFYMSLTGDAVLSVYDDSNHWSDCLLDHYIYDRYYRFAYDLEFWEEGDEGVLAYVRGRILLPLANDLINQLSQEKLHVDLYPTLDKTLEYLNFLIHYTSKAQEMLDAIEITMGSSNSMTEHKDESATTYEAEGTTLLANSTVGLSVYDQIYCLLEACSTAIRKYGAYGSLLPIVDALDTAIGEVDIESPDSWQAEYVQRVSRLSKWYRMLGHAFTGNDTYERLLQELITAQEESPFIHETYFNNYIRDLDGQDNVFNLECLQYLLLHHDIEKGDCESFEQHVQSIDHPYFKMPFERFGEIHGLVDLKSREDSNDIVYFLLLLKAIYRFYLDQLDQDLWQELLRLWSMYEKRKFQDYHAQWLCAKYMVALAVHMGDREQAELIKQDLAITFDEPLHRRNYSSAYQWSPLAFYTMAQIDEALGHLDLAQDNYDKAYVTHAYTQARWAYYKSKCASLWNVNQLSTAETKSAETVTKPIELERKPTTTVMKSTTSEIRTTVTEISLVVAEIKPDFEAVIQENKGKFFTMDEYKEYFNAHMIYLYR
>NZ_CP019721.1|WP_077707835.1|525278_526697_+|sodium:solute-symporter-family-protein
MDSLTIIWVIICAYLLLNLLVGVYCHIRVKDSTDYLLAGRRIGVLMTAGTLAATEIGGGSTVGVAAKAYGSWGLSAGWYVVSAGIGVILVALIAPLLRRAMATTVPEIIGRRFGASSHLITSILSMLATITLAGVQITATATIISVLTGLSTELAILICGAVLVIYTMSGGMWSVTMTDVIHFFVLVGGFSLAVPFVLHNVGGWESVVAKLPPEQLGFTKVGWKTIIGLIIMYFMTFSTGQESVQRYFAAKDERTAVLGSIICGIIMALFAFVPAILGLVALAEFPNIEANNAVATVALNLMPPIMAGFVMAAVVSATLSSGAGDLLGAATVFTKDIVEHHFGKSLTDAQLTNYSRLCVLFLGIIAIIISLVSKAIIPMLVFAFTMRSAGPFAAFLLGLTWKNATAGAGIWSIVLGSIAGVYWEFVGNPYGIMSIIFGSIVSLIVFVAVVCIERAMGKPPAPPAIPDDVKEI
>NZ_CP019721.1|WP_077707834.1|524423_525005_-|hypothetical-protein
MIQRILMLALVLLAFTMPTEAITFQELKTSPQFKLVHQHEYEKPSAIVNDGGMYVYLNTYSVEVQKYAPPQYTLSAIYYVVHTSHYQAEIIEKRLTVNYDANYSLATLIKSSHTMNPSPSMLALIEASESKSGLFMSDSDRAIYTLDGALKKNPSSEGTRNLPLNRKNIIMYDLADAMFMSAYQQHFDDIVVQ
>NZ_CP019721.1|WP_077707833.1|523845_524415_-|hypothetical-protein
MKRIYLLSLWLLACLVLPMKGQAVSQAELLNPEHYQHIDSTVDSGRGDGKYLDLSSIKAVDAPDGHRRVEATIYVLMPASNLIQGIQLQYDYDLEQSLRHLITIHDRGLQQGANTPYISIWRAKQENSGIIGTVTGGIAFNNEGKTRRQRLQKEHLEAMILPPQFGMERYTIANIIYQKAYGVAYDDEP
>NZ_CP019721.1|WP_077707832.1|521989_523246_-|hypothetical-protein
MLRKSVMMMALAVTFTMNVSAIQIEVPAGQPAMPGSDASIPANAYENYRHVNEVAEQNAESYSEFIKSQPMNPKSGMDKLYRERPGLAKALELADYSQSTVVLIHEGNKNIRLSVPNVSFRGDTVESKSGKGPLYAVRSLSSFLVVGPPHGKELNKYAEEEGKYTYPGLHDTSWKLMSNNARVMYTEFTPNDSKTTYGITYGGWVNTEDPYQDKSPEVVMSNYIIPSIESLSGLDTYSRVEHWGNFSYRVPKTAKLVSETVENSQYDVRTYEDTGSKIRVVRTSILGEKRDGTVIKSSILSFLRKYNDLETPTQYAVVWNNGIAGSLIDSYKPNGESYLRHVVKDSVYFYSYRINYDESKTSYTHKQWRDMIEYVGFDDAVKLRKGPQWREDGTYKEKLESGPIFIPWYMEWVKLLNQ
>NZ_CP019721.1|WP_077707830.1|519910_521167_-|hypothetical-protein
MLRKSLIMMALATAFTMNVNAVQIKVPEGQPPVPGADASIPANAYENYSHINEKAIQEAEAFSAKVQKTVEKPSIAIEKVFKEKSGLAKAVKLGEYSQSTVILLHDEKNNIRLAVPNISLRGDTVESKSSDGPLFVVRGFTSILMVGPPHGKEFSKRMHNEGVYTYSGLENASWKILKAKTHVMYTEFTPKNTNTTYGITYLGGGDVKEPYQDKIAEVVMSNYIIPSIESLSRLDNYSHVKHWDNFSYRIPKKAKLVSEVMEDNKYEVRTYEDAGIKIRVLRFQIDPNVVDKSLAKKQIFAFLNKYGDLEAPTQYATVWNNGLPGFLVDRYKSNGGSYLRHFTKDSEYYYSYRIDYDESKSSYKHKQLRDMVEYVDFDNVESLRKAPQWRISDSHKKKLDADPIFNPWYMEWIKILTQ
>NZ_CP019721.1|WP_077707829.1|519277_519853_-|TonB-dependent-receptor
MKRKYLITGLVIGLQLVSGYSYESDASWLSKTWDRLETNAAKQSYDWPKAEQYTHYAGGQIVGTTLPDEDMMILGVSLGNTFDSVKASLGQPTKETSRGLTYGGVTFGNFKMDGVGPIVTYMMIENRDATTHRGIAVGDSMRKVLNVYGRPDLVDSNNRWFYGKYRYRTDMMHGIQFEQKGDKVSKILIYK
>NZ_CP019721.1|WP_077707828.1|518291_518828_-|flavin-reductase
MKPFETKDYKAFTMFENHWALVTAGTLDNFNTCTVSWGSMGNIWGPNGGDISTVTVYIHPARYTQEFMAKYDTFTVSFFPESYRKALGYLGSHSGRDENKVANSGLTPVAVGDGVTFKEAELTFVCKKLYEHQFDEAHLAEKVKDYYASNPAVYTQTGHDRWEPHYMYIGEVVDAIED
>NZ_CP019721.1|WP_077707838.1|533722_535978_-|hypothetical-protein
MRFLTLSTTGIFNAIRPSLFPPIEGKETTTFLLALDYYVPDRCFLEDEQEDVEAARKSYDLECKRIRAFVKALCNDWGKPIEELRTEIINCLPEFISHGTYNGEPLLSEPRDGYYTIYPMYKSYRGRDMLFPTHQSSKEEAQYIFDHMLRYFLKAFFEPDAFFGYLDGAFHIDTPLSVTTVQQILEDLERETVPSPLSVSSISNTHTMDEPTIINTEFLLITDAFGAYMVQAMEGDTESEQLAALTEDPFVCEMCCSLHKCFMINNRCFSISIYDECNIWIDKLLDAYAMHDYLQILSVYNDDFPCYDNGVIGYEKQYLVEPLLDNLVKDLTREKLLVQLSPQNEQRKDYLNFILTHDESVQSIFEEIYEKRLDGRDIYKQQDLAKVLTLDVRLCCTFYCMIDACRHAFNRRMYASILPIVDKLDTQLAKVQISATDTWQVEYLVKASRISQWYRALAYACLGDERIEPILQDLMVMQQQDPVLYKEQMDSIFENLDDPEHAFNTEDLRYALLHYYVETNNQPGYERYIKELYPPILGIDSDYKVQKNILLYGENGKYCENYSNRDFYLWLKALWTFYLDDIDKEFWNEIADQWEQQDYIPIFYGINDYELCANYMIKLAVHFGDIQRAEKYKKEFDMAIPNKKEPMEDAPSGYRWPFFDYYLIAQVNESLGNIEIAKEHYHKALSLATFGEARWEQYEEQHGGIWKTYKDFGYSGPDLKFEDWIKDSTVTYDTIEEYKKVLDKYVFYMYK
>NZ_CP019721.1|WP_077707839.1|536094_536631_-|hydrolase
MFHIVDVDNTLVFTDELNTAGYVHALACMALEPRKVVPRITREIVQEWYPQLSEYDLVHIATLKQSYVESHLDMSQLNSSVARVLSTYGRERCALWTAANPERIRMLLRHHMVTDYRAIRFSNKTENDISHAVQDFCVLFDCEPEELCFHEDNPEVINHLRKLGMTVMAVEVKAETVA
>NZ_CP019721.1|WP_077708640.1|536657_537653_-|DNA-processing-protein-DprA
MWHTPTVVLLIEKGHNMNISPIALKIWAVHNTTSRITTRKSFHDNWKTEDEFLAMMSDIPNIDDVVHDLSVAVDDMDWMDGAVCCFDADFPVINESAPKGDRPYLLFYKGDLSLLSDLNRNVAVIGYTTPNEDIMARESKIVEQLVQRSQHIVSGLAKGCDAIGHTVCMDYGGKTIAILPSPLNAISPADHRDMAHQIIEKGGLVISEYYNGPRSRNEAINRYVERDRLQALFAKAVVLIASYEGRDGDSGSRHAMGKAYSYGHLACAMYDETTDSEVLEMKLNRNLISRQKARQLVTIPSVVSAAGYTSVTVDDLVGLVNPALEAQQKLF
>NZ_CP019721.1|WP_077707840.1|537606_538281_-|phosphoribosyltransferase
MEVHMEQLIRRFTLSSNEYLSRDCVGYYRDLYLRFREPGNPDFLNTLKNTLNNYCPSVLKSARQEVYDRVKRDIPDIMKAEKLEEAVVAVVPRSKAFMSPNQLGFRDAVQECVRILQANGYSGITDGISCIMRHTNTKTTHIHKNLPGFDNCGSEPYVGITNDTCHINADVVRDKTVILIDDIYTKTVNVDEDCIQALYDAGAARVVFYAVAYTYRRSSYRKGA
>NZ_CP019721.1|WP_077707841.1|538619_539423_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MLGTVTIALEVQNRGSLPAFPGRYLHAALFSILSHVDADEATWWHDMEGIKPFSLQLSFKEPRQDNIIRRGDILYLHVSVWHSELWGLLEGISEGLELVFGRLRTTIVGVRYGAPFNLLLKIDNELELISRRLSAKQVGRITFEVMTPTSFNGTHGDITFPTASLIFSSLVDKWNAGDMTDALNKDLIRTVVEKVTLERWEGYTKRVFYGRDRGLTGFVGKFIFNISRLTEEENQLITILALFGQHCGIGRLSSQSLGQVHVTLQNK
>NZ_CP019721.1|WP_077707842.1|539422_541432_-|TIGR03986-family-CRISPR-associated-RAMP-protein
MAGKGKSKNRHAASEAFFARNNPGMDVEKVANERHYGGNRGGQNRSGGYNNSYNNQGGNRSGGNSKYPSEPASAAYNFVRLPEHVIPAEFYNGHFEGVTKDVLKAYCDHVQQADTHTGYIDLTITTETPLFIGGPSKQDEDTPLEFYGGQDNPTIPGASLKGMVKEIFKIVTASSFRPYQRGTGLGDFEDRYLYFRDFASSIKSLKEYYASRMVGMEKNGKGEMKAATKATPGFIIQTVDNNYFAVPSESRKMSYSGDYEMQKKKDTPSIDWNDQYVNIHTGRMNSKKSYMRITRPGNFEGKRIPILQECIDSYKDDKNRGTLNLLDKKVGKSGDAAKNYTRCDDVKFVVPCFFSEKDGIVEHFGHGRFYRIAYDLKISDHLPTTLEQHNNGVDLCDSVFGYGDNWAGRLSFSDAHVVGPVRMCQSDYPHPLMGPNPTSFQLYLEQDVDNHSTYNHWGHEGASIRGYKMYWHQPLAKAKDWTRTEAEKAIQGTRKIRPVDTGVTFKSRIHFERLSSVELGALLMSLDLDHYSGGNRRTYYKLGMGKSIGFGSIKLESAVTVFDSKERYGSLFGGNTWNTGASITTPNEYVESFTQYRDNALGSNISSYKAMLDDLFMMLDWNIANGPNAAKNWTEGISMMTIKNNKMDPRIKYRSKLDTPKSFIAKWSK
>NZ_CP019721.1|WP_077707843.1|541433_541997_-|TIGR03984-family-CRISPR-associated-protein
MSKQLHSYEGVYTRTCGICGPTANVNVLAVAKEQMKQEGLVITWSVHEVKWGYYKQGGFQFSDGTTDVDLAYLQDMRIFNEMEELRLTVQHGEVVYRYINDEAGKAVIYVDSSSRMIGEVDAGRTQLNRVESFTSLIDTGRKLSQIIPVSTTKQYCYLTTRNYIGYLDNHQASYTDYRYVKIEAKEV
>NZ_CP019721.1|WP_077707844.1|541989_543324_-|CRISPR-associated-protein
MLNSASVIGRYTLTGTVKLTSPLVIRAGVSNDILNDTVDDIVVTYHDGQPFIPGTSLAGVLRQAIQGLEPVSEDVLFGSIDDKGTQSALQINDIPLDNTNIVVRDGICIDDVRGVTKDGAKYDFEVIESGATGRLRIDCVIRQCHENQVDKIERALVALANLLKNGISVGARTVNGLGRIACKDISLEHYDFTKPEHVKAWLLRKAGTSVAIPERCMIAEKDLVIDIECCLEDTVLIKSIFEEAWEDKSVALFIPGTSIKGVLRHYCSRILQALGRSNQAVDALFGYSIEKTNESRKGRVMVDEVYFDKSFTQEEQPRIRVDRFTGGAMNGALFQDHPVRKGKGKELVFPLRMTVKDCSDSEAGLVLLLVKDLMTGQITLGANRTIGYGRIKGNSVAVQYHGESYGIDGTGKVTEGESTKLEALVQALHQSTEDTMLAKEGAHE
>NZ_CP019721.1|WP_077707845.1|543337_544918_-|hypothetical-protein
MEQVNITITVKSPTLIANSSTAGVLTSTRGSIDGRVLRGLFASQFISSHKLGREAHKNQDFMNLFYGDLRFVAAYKHTPKGTSFPAPLSLQKNKNAEGYASDDVVDFYTGKDLLGFKGVKGFVIVDGKECSPVQIETAIKLHMSRSLEQERVQGRSNEGRNIFNYEYIEPNQVFVGSVVGPKAALEEFVRQFPKQLDCHIGRSRRTEYGHCIVEIGDITAVPTPVNSGNSIYVRLHTPLVLGNESIGHVVAQAVQSIGSDISVGTVFASYQEEQSFNSIWGVRSSAEASASAGSIVELVKESGWSQDDLDKLQNILYNGMGTRLQEGYGQGRLWTPGEFKMVKLGKQEAPKLKSLHTLTQEIAKKVLEKQVIVNARLRAAHDVDTYIKRTMSRSGISKHFASVLLTELGTNHETGHKQLQQFLEDKKAEGQKKNEPRVIEKNLREFHLGHAYTRSETKRVNLMEYIIDFDAPTLVAACLAKSGESGTYYEIPAELVDMVGLDKQKLSNVVAYEYWTYFFRHIRKIK
>NZ_CP019721.1|WP_077707846.1|544905_545553_-|CRISPR-associated-protein
MYTLTIKLLSPTMLMSGQGDVNTDSTIVHDRYGIPFIPAKRVRGVLYESAIEVAEMMHAAGLNTFTIDDVKVLFNRLEGAEDNPRLSISNLTIADYDVVASELAALEEQYPAVFTKERVLEEYTSMRYYTSIDQVTGTALEGTLHNSRVLNRALAFSGQIDVEDMTEIERLILACAVRNLTGIGGKRNRGFGQVECTIDDASFDLESLGGTLWNK

Crispr_ID: NZ_CP019721_4

• CRISPR_ID: NZ_CP019721_4
• CRISPR_location: 532384-533286
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 12 spacers
• Cas_protein_info: cas6,csm3gr7,csx19,csx10gr5

Consensus repeat of NZ_CP019721_4

Consensus_repeat	Method
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	CRISPRCasFinder
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	CRT
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	PILER-CR

spacers of NZ_CP019721_4

>4.1|532419|38|NZ_CP019721|CRISPRCasFinder
CTAATCATTGATACTTGTGGTATGCTTGAAGCTTACTC
>4.2|532492|35|NZ_CP019721|CRISPRCasFinder,CRT
AGGATATTATGAAAAAAGAATATTTAGTTGAAAAA
>4.3|532562|39|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
TTTTGGCAATAACGATTCCTCGATCATGAATCGTTTACC
>4.4|532636|38|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
TTGGCTAAAATTGGTATAGATGGAAGTCAATATGGAAC
>4.5|532709|34|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
CTAAATGGCTTCAAAAGCTAAAAGATACTAATCA
>4.6|532778|38|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
ATAATAACGATTACGACACAATTTATTTTTGTGTTGAG
>4.7|532851|37|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
TCTAAAAAACCAATGCTTAAAATACAAATGGATTTAA
>4.8|532923|40|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
AAGAAGGTCATCGAATACGTGATGACCATATGACATAGAC
>4.9|532998|36|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
TCATTAGTCATCTTAAGTTTAATTGTTGTATTCATA
>4.10|533069|36|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
ACCCTAATTCTTTCGACTCTTTCATATTTATTATTA
>4.11|533140|38|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
AATTAATACAGATGGTCTTGATAAACTTTGGGGCGAAC
>4.12|533213|39|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
CCAAAAATTGTATTGCTATAGTTCCCAAATTGGATAGTA

CRISPR arrays and Neighbor proteins around NZ_CP019721_4

CRISPR arrays

The CRISPR arrays of NZ_CP019721_4

>merge|NZ_CP019721|4|532384-533286|CRISPRCasFinder,CRT,PILER-CR
ATTAATATACTATAAACGTTAATTGTTGTTGCAACCTAATCATTGATACTTGTGGTATGCTTGAAGCTTACTCGTTTCAATACCGTAAACGGTAAGCACTGTTGCAGCAGGATATTATGAAAAAAGAATATTTAGTTGAAAAAGTTTCAATACCGTAAACGGTAAGCACTGTTGCAACTTTTGGCAATAACGATTCCTCGATCATGAATCGTTTACCGTTTCAATACCGTAAACGGTAAGCACTGTTGCAACTTGGCTAAAATTGGTATAGATGGAAGTCAATATGGAACGTTTCAATACCGTAAACGGTAAGCACTGTTGCAACCTAAATGGCTTCAAAAGCTAAAAGATACTAATCAGTTTCAATACCGTAAACGGTAAGCACTGTTGCAACATAATAACGATTACGACACAATTTATTTTTGTGTTGAGGTTTCAATACCGTAAACGGTAAGCACTGTTGCAACTCTAAAAAACCAATGCTTAAAATACAAATGGATTTAAGTTTCAATACCGTAAACGGTAAGCACTGTTGCAACAAGAAGGTCATCGAATACGTGATGACCATATGACATAGACGTTTCAATACCGTAAACGGTAAGCACTGTTGCAACTCATTAGTCATCTTAAGTTTAATTGTTGTATTCATAGTTTCAATACCGTAAACGGTAAGCACTGTTGCAACACCCTAATTCTTTCGACTCTTTCATATTTATTATTAGTTTCAATACCGTAAACGGTAAGCACTGTTGCAACAATTAATACAGATGGTCTTGATAAACTTTGGGGCGAACGTTTCAATACCGTAAACGGTAAGCACTGTTGCAACCCAAAAATTGTATTGCTATAGTTCCCAAATTGGATAGTAGTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC

>NZ_CP019721|4|3|532384-533286|CRISPRCasFinder
ATTAATATACTATAAACGTTAATTGTTGTTGCAAC	CTAATCATTGATACTTGTGGTATGCTTGAAGCTTACTC
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAGC	AGGATATTATGAAAAAAGAATATTTAGTTGAAAAA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	TTTTGGCAATAACGATTCCTCGATCATGAATCGTTTACC
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	TTGGCTAAAATTGGTATAGATGGAAGTCAATATGGAAC
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	CTAAATGGCTTCAAAAGCTAAAAGATACTAATCA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	ATAATAACGATTACGACACAATTTATTTTTGTGTTGAG
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	TCTAAAAAACCAATGCTTAAAATACAAATGGATTTAA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	AAGAAGGTCATCGAATACGTGATGACCATATGACATAGAC
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	TCATTAGTCATCTTAAGTTTAATTGTTGTATTCATA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	ACCCTAATTCTTTCGACTCTTTCATATTTATTATTA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	AATTAATACAGATGGTCTTGATAAACTTTGGGGCGAAC
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	CCAAAAATTGTATTGCTATAGTTCCCAAATTGGATAGTA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC

>NZ_CP019721|4|2|532457-533286|CRT
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAGC	AGGATATTATGAAAAAAGAATATTTAGTTGAAAAA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	TTTTGGCAATAACGATTCCTCGATCATGAATCGTTTACC
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	TTGGCTAAAATTGGTATAGATGGAAGTCAATATGGAAC
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	CTAAATGGCTTCAAAAGCTAAAAGATACTAATCA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	ATAATAACGATTACGACACAATTTATTTTTGTGTTGAG
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	TCTAAAAAACCAATGCTTAAAATACAAATGGATTTAA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	AAGAAGGTCATCGAATACGTGATGACCATATGACATAGAC
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	TCATTAGTCATCTTAAGTTTAATTGTTGTATTCATA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	ACCCTAATTCTTTCGACTCTTTCATATTTATTATTA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	AATTAATACAGATGGTCTTGATAAACTTTGGGGCGAAC
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	CCAAAAATTGTATTGCTATAGTTCCCAAATTGGATAGTA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC

>NZ_CP019721|4|2|532527-533286|PILER-CR
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	TTTTGGCAATAACGATTCCTCGATCATGAATCGTTTACC
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	TTGGCTAAAATTGGTATAGATGGAAGTCAATATGGAAC
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	CTAAATGGCTTCAAAAGCTAAAAGATACTAATCA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	ATAATAACGATTACGACACAATTTATTTTTGTGTTGAG
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	TCTAAAAAACCAATGCTTAAAATACAAATGGATTTAA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	AAGAAGGTCATCGAATACGTGATGACCATATGACATAGAC
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	TCATTAGTCATCTTAAGTTTAATTGTTGTATTCATA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	ACCCTAATTCTTTCGACTCTTTCATATTTATTATTA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	AATTAATACAGATGGTCTTGATAAACTTTGGGGCGAAC
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	CCAAAAATTGTATTGCTATAGTTCCCAAATTGGATAGTA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019721.1|WP_077707840.1|537606_538281_-|phosphoribosyltransferase	unknown	unknown	gnl|CDD|223970
NZ_CP019721.1|WP_077707841.1|538619_539423_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	gnl|CDD|227838
NZ_CP019721.1|WP_077708640.1|536657_537653_-|DNA-processing-protein-DprA	unknown	unknown	gnl|CDD|376794
NZ_CP019721.1|WP_077707834.1|524423_525005_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_187658828.1|531180_531345_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707839.1|536094_536631_-|hydrolase	unknown	unknown	unknown
NZ_CP019721.1|WP_077707829.1|519277_519853_-|TonB-dependent-receptor	unknown	unknown	unknown
NZ_CP019721.1|WP_077707832.1|521989_523246_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707833.1|523845_524415_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707846.1|544905_545553_-|CRISPR-associated-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|377130
NZ_CP019721.1|WP_077707842.1|539422_541432_-|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|274902
NZ_CP019721.1|WP_077707828.1|518291_518828_-|flavin-reductase	unknown	unknown	gnl|CDD|224766
NZ_CP019721.1|WP_077707843.1|541433_541997_-|TIGR03984-family-CRISPR-associated-protein	csx19	cls001376_csx19_CAS-III-D	gnl|CDD|274900
NZ_CP019721.1|WP_077707845.1|543337_544918_-|hypothetical-protein	csx10gr5	cls000715_csx10gr5_CAS-III-D	unknown
NZ_CP019721.1|WP_077707830.1|519910_521167_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707838.1|533722_535978_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707836.1|527040_529434_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707844.1|541989_543324_-|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl|CDD|187857
NZ_CP019721.1|WP_077707835.1|525278_526697_+|sodium:solute-symporter-family-protein	unknown	unknown	gnl|CDD|271357
NZ_CP019721.1|WP_077707837.1|529870_531175_+|cytosine-permease	unknown	unknown	gnl|CDD|236821

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP019721.1|WP_077707841.1|538619_539423_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	3.3e-15	51.5	0.0
NZ_CP019721.1|WP_077707842.1|539422_541432_-|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	1.7e-156	517.6	0.7
NZ_CP019721.1|WP_077707845.1|543337_544918_-|hypothetical-protein	csx10gr5	cls000715_csx10gr5_CAS-III-D	9.6e-13	42.7	0.8
NZ_CP019721.1|WP_077707843.1|541433_541997_-|TIGR03984-family-CRISPR-associated-protein	csx19	cls001376_csx19_CAS-III-D	1.4e-49	163.0	0.2
NZ_CP019721.1|WP_077707844.1|541989_543324_-|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	1.6e-34	114.6	0.0
NZ_CP019721.1|WP_077707846.1|544905_545553_-|CRISPR-associated-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	9.6e-38	124.4	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP019721.1|WP_077707841.1|538619_539423_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl|CDD|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.40482e-05
NZ_CP019721.1|WP_077707842.1|539422_541432_-|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl|CDD|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	8.61432e-150
NZ_CP019721.1|WP_077708640.1|536657_537653_-|DNA-processing-protein-DprA	gnl|CDD|376794	pfam02481, DNA_processg_A, DNA recombination-mediator protein A. The SMF family, of DNA processing chain A, dprA, are a group of bacterial proteins. In H. pylori, dprA is required for natural chromosomal and plasmid transformation. It has now been shown that DprA is found to bind cooperatively to single-stranded DNA (ssDNA) and to interact with RecA. In the process, DprA-RecA-ssDNA filaments are produced and these filaments catalyze the homology-dependent formation of joint molecules. While the E.coli SSB protein limits access of RecA to ssDNA, DprA alleviates this barrier. It is proposed that DprA is a new member of the recombination-mediator protein family, dedicated to natural bacterial transformation.	7.7447e-41
NZ_CP019721.1|WP_077707843.1|541433_541997_-|TIGR03984-family-CRISPR-associated-protein	gnl|CDD|274900	TIGR03984, hypothetical_protein_FrEUN1fDRAFT_5778, CRISPR-associated protein, TIGR03984 family. Members of this protein family are found exclusively in CRISPR-containing organisms, in operon contexts with RAMP (repeat-associated mystery protein) proteins also linked to CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats).	4.04648e-46
NZ_CP019721.1|WP_077707828.1|518291_518828_-|flavin-reductase	gnl|CDD|224766	COG1853, COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only].	2.70772e-14
NZ_CP019721.1|WP_077707844.1|541989_543324_-|CRISPR-associated-protein	gnl|CDD|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	2.90366e-15
NZ_CP019721.1|WP_077707840.1|537606_538281_-|phosphoribosyltransferase	gnl|CDD|223970	COG1040, ComFC, Predicted amidophosphoribosyltransferases [General function prediction only].	0.00821492
NZ_CP019721.1|WP_077707846.1|544905_545553_-|CRISPR-associated-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.49345e-12
NZ_CP019721.1|WP_077707835.1|525278_526697_+|sodium:solute-symporter-family-protein	gnl|CDD|271357	cd10322, SLC5sbd, Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain. This family represents the solute-binding domain of SLC5 proteins (also called the sodium/glucose cotransporter family or solute sodium symporter family) that co-transport Na+ with sugars, amino acids, inorganic ions or vitamins. Family members include: the human glucose (SGLT1, 2, 4, 5), chiro-inositol (SGLT5), myo-inositol (SMIT), choline (CHT), iodide (NIS), multivitamin (SMVT), and monocarboxylate (SMCT) cotransporters, as well as Vibrio parahaemolyticus glucose/galactose (vSGLT), and Escherichia coli proline (PutP) and pantothenate (PutF) cotransporters. Vibrio parahaemolyticus Na(+)/galactose cotransporter (vSGLT) has 13 transmembrane helices (TMs): TM-1, an inverted topology repeat: TMs1-5 and TMs6-10, and TMs 11-12 (TMs numbered to conform to the solute carrier 6 family Aquifex aeolicus LeuT). One member of this family, human SGLT3, has been characterized as a glucose sensor and not a transporter. Members of this family are important in human physiology and disease.	3.8582e-92
NZ_CP019721.1|WP_077707837.1|529870_531175_+|cytosine-permease	gnl|CDD|236821	PRK11017, codB, cytosine permease; Provisional.	1.42691e-79

Protein sequences

>NZ_CP019721.1|WP_187658828.1|531180_531345_+|hypothetical-protein
MAIHKLSAILGTIIMGIGSFITCLATSESTITLGNGMLVVSIIMMGFGYSKWQP
>NZ_CP019721.1|WP_077707837.1|529870_531175_+|cytosine-permease
MSKEKLEFVEPVNTNTDNEYSREPVPLGSRKSCFSLTIVWTGFVFLVTSMMAGGGLAAGLTFNELLLAMVLGNIFLCIIAGLVSVIAYKTGLTFALLTRYSFGQEGSRIASLFVPIVNLGWYTIQAALYGHFIAQVFNLSYIGEIIAMMLSAVIMGIFAVLGIKSLAVFGYIAIPSIVFLSLGTAARSVQTIGGWQELFNYVPLQSIDLLSGITIVIGTWILSTATCIADIMRYGKSKKDVITASTIGLLGGNTLMISCGAIAGVAMNDGDLINVLLSFGLVFPSLLLLTTNIFTTNGANLYSTSLNLANSFKLNRNIMLAVLIAISALATMTQPYKIDSLFVFLSTLGIIVPPLCGIILADFYLVHRGKYIDYNKATFKKWNLVPWITWAIALVCVKFIPFGLASLNGIVIGALLYALITYIVKPNVVSKSKG
>NZ_CP019721.1|WP_077707836.1|527040_529434_-|hypothetical-protein
MYNVTITTTGIFDEIRPSLFPPIEGKEGITFMNALVYRVDPKSSFEEGDAITDNDPEFALERERIRAFVAALCEAYGKPYGELRDEFVEALPEFMLYGTYKGQALLSTGRNGYYQVFPMYKSNRGRRLLFQDGYAPNQITKYICDHMLRYFVITLFSNIGAFGSDAGVQHIATPLSLYGLHQALDDVDRAYLSELITVNSLDNTYSMDASNQSEFLLLADALGAYMVQAMDGYTESERLDSLSQDPFFRKICEPVHRFYMSLTGDAVLSVYDDSNHWSDCLLDHYIYDRYYRFAYDLEFWEEGDEGVLAYVRGRILLPLANDLINQLSQEKLHVDLYPTLDKTLEYLNFLIHYTSKAQEMLDAIEITMGSSNSMTEHKDESATTYEAEGTTLLANSTVGLSVYDQIYCLLEACSTAIRKYGAYGSLLPIVDALDTAIGEVDIESPDSWQAEYVQRVSRLSKWYRMLGHAFTGNDTYERLLQELITAQEESPFIHETYFNNYIRDLDGQDNVFNLECLQYLLLHHDIEKGDCESFEQHVQSIDHPYFKMPFERFGEIHGLVDLKSREDSNDIVYFLLLLKAIYRFYLDQLDQDLWQELLRLWSMYEKRKFQDYHAQWLCAKYMVALAVHMGDREQAELIKQDLAITFDEPLHRRNYSSAYQWSPLAFYTMAQIDEALGHLDLAQDNYDKAYVTHAYTQARWAYYKSKCASLWNVNQLSTAETKSAETVTKPIELERKPTTTVMKSTTSEIRTTVTEISLVVAEIKPDFEAVIQENKGKFFTMDEYKEYFNAHMIYLYR
>NZ_CP019721.1|WP_077707835.1|525278_526697_+|sodium:solute-symporter-family-protein
MDSLTIIWVIICAYLLLNLLVGVYCHIRVKDSTDYLLAGRRIGVLMTAGTLAATEIGGGSTVGVAAKAYGSWGLSAGWYVVSAGIGVILVALIAPLLRRAMATTVPEIIGRRFGASSHLITSILSMLATITLAGVQITATATIISVLTGLSTELAILICGAVLVIYTMSGGMWSVTMTDVIHFFVLVGGFSLAVPFVLHNVGGWESVVAKLPPEQLGFTKVGWKTIIGLIIMYFMTFSTGQESVQRYFAAKDERTAVLGSIICGIIMALFAFVPAILGLVALAEFPNIEANNAVATVALNLMPPIMAGFVMAAVVSATLSSGAGDLLGAATVFTKDIVEHHFGKSLTDAQLTNYSRLCVLFLGIIAIIISLVSKAIIPMLVFAFTMRSAGPFAAFLLGLTWKNATAGAGIWSIVLGSIAGVYWEFVGNPYGIMSIIFGSIVSLIVFVAVVCIERAMGKPPAPPAIPDDVKEI
>NZ_CP019721.1|WP_077707834.1|524423_525005_-|hypothetical-protein
MIQRILMLALVLLAFTMPTEAITFQELKTSPQFKLVHQHEYEKPSAIVNDGGMYVYLNTYSVEVQKYAPPQYTLSAIYYVVHTSHYQAEIIEKRLTVNYDANYSLATLIKSSHTMNPSPSMLALIEASESKSGLFMSDSDRAIYTLDGALKKNPSSEGTRNLPLNRKNIIMYDLADAMFMSAYQQHFDDIVVQ
>NZ_CP019721.1|WP_077707833.1|523845_524415_-|hypothetical-protein
MKRIYLLSLWLLACLVLPMKGQAVSQAELLNPEHYQHIDSTVDSGRGDGKYLDLSSIKAVDAPDGHRRVEATIYVLMPASNLIQGIQLQYDYDLEQSLRHLITIHDRGLQQGANTPYISIWRAKQENSGIIGTVTGGIAFNNEGKTRRQRLQKEHLEAMILPPQFGMERYTIANIIYQKAYGVAYDDEP
>NZ_CP019721.1|WP_077707832.1|521989_523246_-|hypothetical-protein
MLRKSVMMMALAVTFTMNVSAIQIEVPAGQPAMPGSDASIPANAYENYRHVNEVAEQNAESYSEFIKSQPMNPKSGMDKLYRERPGLAKALELADYSQSTVVLIHEGNKNIRLSVPNVSFRGDTVESKSGKGPLYAVRSLSSFLVVGPPHGKELNKYAEEEGKYTYPGLHDTSWKLMSNNARVMYTEFTPNDSKTTYGITYGGWVNTEDPYQDKSPEVVMSNYIIPSIESLSGLDTYSRVEHWGNFSYRVPKTAKLVSETVENSQYDVRTYEDTGSKIRVVRTSILGEKRDGTVIKSSILSFLRKYNDLETPTQYAVVWNNGIAGSLIDSYKPNGESYLRHVVKDSVYFYSYRINYDESKTSYTHKQWRDMIEYVGFDDAVKLRKGPQWREDGTYKEKLESGPIFIPWYMEWVKLLNQ
>NZ_CP019721.1|WP_077707830.1|519910_521167_-|hypothetical-protein
MLRKSLIMMALATAFTMNVNAVQIKVPEGQPPVPGADASIPANAYENYSHINEKAIQEAEAFSAKVQKTVEKPSIAIEKVFKEKSGLAKAVKLGEYSQSTVILLHDEKNNIRLAVPNISLRGDTVESKSSDGPLFVVRGFTSILMVGPPHGKEFSKRMHNEGVYTYSGLENASWKILKAKTHVMYTEFTPKNTNTTYGITYLGGGDVKEPYQDKIAEVVMSNYIIPSIESLSRLDNYSHVKHWDNFSYRIPKKAKLVSEVMEDNKYEVRTYEDAGIKIRVLRFQIDPNVVDKSLAKKQIFAFLNKYGDLEAPTQYATVWNNGLPGFLVDRYKSNGGSYLRHFTKDSEYYYSYRIDYDESKSSYKHKQLRDMVEYVDFDNVESLRKAPQWRISDSHKKKLDADPIFNPWYMEWIKILTQ
>NZ_CP019721.1|WP_077707829.1|519277_519853_-|TonB-dependent-receptor
MKRKYLITGLVIGLQLVSGYSYESDASWLSKTWDRLETNAAKQSYDWPKAEQYTHYAGGQIVGTTLPDEDMMILGVSLGNTFDSVKASLGQPTKETSRGLTYGGVTFGNFKMDGVGPIVTYMMIENRDATTHRGIAVGDSMRKVLNVYGRPDLVDSNNRWFYGKYRYRTDMMHGIQFEQKGDKVSKILIYK
>NZ_CP019721.1|WP_077707828.1|518291_518828_-|flavin-reductase
MKPFETKDYKAFTMFENHWALVTAGTLDNFNTCTVSWGSMGNIWGPNGGDISTVTVYIHPARYTQEFMAKYDTFTVSFFPESYRKALGYLGSHSGRDENKVANSGLTPVAVGDGVTFKEAELTFVCKKLYEHQFDEAHLAEKVKDYYASNPAVYTQTGHDRWEPHYMYIGEVVDAIED
>NZ_CP019721.1|WP_077707838.1|533722_535978_-|hypothetical-protein
MRFLTLSTTGIFNAIRPSLFPPIEGKETTTFLLALDYYVPDRCFLEDEQEDVEAARKSYDLECKRIRAFVKALCNDWGKPIEELRTEIINCLPEFISHGTYNGEPLLSEPRDGYYTIYPMYKSYRGRDMLFPTHQSSKEEAQYIFDHMLRYFLKAFFEPDAFFGYLDGAFHIDTPLSVTTVQQILEDLERETVPSPLSVSSISNTHTMDEPTIINTEFLLITDAFGAYMVQAMEGDTESEQLAALTEDPFVCEMCCSLHKCFMINNRCFSISIYDECNIWIDKLLDAYAMHDYLQILSVYNDDFPCYDNGVIGYEKQYLVEPLLDNLVKDLTREKLLVQLSPQNEQRKDYLNFILTHDESVQSIFEEIYEKRLDGRDIYKQQDLAKVLTLDVRLCCTFYCMIDACRHAFNRRMYASILPIVDKLDTQLAKVQISATDTWQVEYLVKASRISQWYRALAYACLGDERIEPILQDLMVMQQQDPVLYKEQMDSIFENLDDPEHAFNTEDLRYALLHYYVETNNQPGYERYIKELYPPILGIDSDYKVQKNILLYGENGKYCENYSNRDFYLWLKALWTFYLDDIDKEFWNEIADQWEQQDYIPIFYGINDYELCANYMIKLAVHFGDIQRAEKYKKEFDMAIPNKKEPMEDAPSGYRWPFFDYYLIAQVNESLGNIEIAKEHYHKALSLATFGEARWEQYEEQHGGIWKTYKDFGYSGPDLKFEDWIKDSTVTYDTIEEYKKVLDKYVFYMYK
>NZ_CP019721.1|WP_077707839.1|536094_536631_-|hydrolase
MFHIVDVDNTLVFTDELNTAGYVHALACMALEPRKVVPRITREIVQEWYPQLSEYDLVHIATLKQSYVESHLDMSQLNSSVARVLSTYGRERCALWTAANPERIRMLLRHHMVTDYRAIRFSNKTENDISHAVQDFCVLFDCEPEELCFHEDNPEVINHLRKLGMTVMAVEVKAETVA
>NZ_CP019721.1|WP_077708640.1|536657_537653_-|DNA-processing-protein-DprA
MWHTPTVVLLIEKGHNMNISPIALKIWAVHNTTSRITTRKSFHDNWKTEDEFLAMMSDIPNIDDVVHDLSVAVDDMDWMDGAVCCFDADFPVINESAPKGDRPYLLFYKGDLSLLSDLNRNVAVIGYTTPNEDIMARESKIVEQLVQRSQHIVSGLAKGCDAIGHTVCMDYGGKTIAILPSPLNAISPADHRDMAHQIIEKGGLVISEYYNGPRSRNEAINRYVERDRLQALFAKAVVLIASYEGRDGDSGSRHAMGKAYSYGHLACAMYDETTDSEVLEMKLNRNLISRQKARQLVTIPSVVSAAGYTSVTVDDLVGLVNPALEAQQKLF
>NZ_CP019721.1|WP_077707840.1|537606_538281_-|phosphoribosyltransferase
MEVHMEQLIRRFTLSSNEYLSRDCVGYYRDLYLRFREPGNPDFLNTLKNTLNNYCPSVLKSARQEVYDRVKRDIPDIMKAEKLEEAVVAVVPRSKAFMSPNQLGFRDAVQECVRILQANGYSGITDGISCIMRHTNTKTTHIHKNLPGFDNCGSEPYVGITNDTCHINADVVRDKTVILIDDIYTKTVNVDEDCIQALYDAGAARVVFYAVAYTYRRSSYRKGA
>NZ_CP019721.1|WP_077707841.1|538619_539423_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MLGTVTIALEVQNRGSLPAFPGRYLHAALFSILSHVDADEATWWHDMEGIKPFSLQLSFKEPRQDNIIRRGDILYLHVSVWHSELWGLLEGISEGLELVFGRLRTTIVGVRYGAPFNLLLKIDNELELISRRLSAKQVGRITFEVMTPTSFNGTHGDITFPTASLIFSSLVDKWNAGDMTDALNKDLIRTVVEKVTLERWEGYTKRVFYGRDRGLTGFVGKFIFNISRLTEEENQLITILALFGQHCGIGRLSSQSLGQVHVTLQNK
>NZ_CP019721.1|WP_077707842.1|539422_541432_-|TIGR03986-family-CRISPR-associated-RAMP-protein
MAGKGKSKNRHAASEAFFARNNPGMDVEKVANERHYGGNRGGQNRSGGYNNSYNNQGGNRSGGNSKYPSEPASAAYNFVRLPEHVIPAEFYNGHFEGVTKDVLKAYCDHVQQADTHTGYIDLTITTETPLFIGGPSKQDEDTPLEFYGGQDNPTIPGASLKGMVKEIFKIVTASSFRPYQRGTGLGDFEDRYLYFRDFASSIKSLKEYYASRMVGMEKNGKGEMKAATKATPGFIIQTVDNNYFAVPSESRKMSYSGDYEMQKKKDTPSIDWNDQYVNIHTGRMNSKKSYMRITRPGNFEGKRIPILQECIDSYKDDKNRGTLNLLDKKVGKSGDAAKNYTRCDDVKFVVPCFFSEKDGIVEHFGHGRFYRIAYDLKISDHLPTTLEQHNNGVDLCDSVFGYGDNWAGRLSFSDAHVVGPVRMCQSDYPHPLMGPNPTSFQLYLEQDVDNHSTYNHWGHEGASIRGYKMYWHQPLAKAKDWTRTEAEKAIQGTRKIRPVDTGVTFKSRIHFERLSSVELGALLMSLDLDHYSGGNRRTYYKLGMGKSIGFGSIKLESAVTVFDSKERYGSLFGGNTWNTGASITTPNEYVESFTQYRDNALGSNISSYKAMLDDLFMMLDWNIANGPNAAKNWTEGISMMTIKNNKMDPRIKYRSKLDTPKSFIAKWSK
>NZ_CP019721.1|WP_077707843.1|541433_541997_-|TIGR03984-family-CRISPR-associated-protein
MSKQLHSYEGVYTRTCGICGPTANVNVLAVAKEQMKQEGLVITWSVHEVKWGYYKQGGFQFSDGTTDVDLAYLQDMRIFNEMEELRLTVQHGEVVYRYINDEAGKAVIYVDSSSRMIGEVDAGRTQLNRVESFTSLIDTGRKLSQIIPVSTTKQYCYLTTRNYIGYLDNHQASYTDYRYVKIEAKEV
>NZ_CP019721.1|WP_077707844.1|541989_543324_-|CRISPR-associated-protein
MLNSASVIGRYTLTGTVKLTSPLVIRAGVSNDILNDTVDDIVVTYHDGQPFIPGTSLAGVLRQAIQGLEPVSEDVLFGSIDDKGTQSALQINDIPLDNTNIVVRDGICIDDVRGVTKDGAKYDFEVIESGATGRLRIDCVIRQCHENQVDKIERALVALANLLKNGISVGARTVNGLGRIACKDISLEHYDFTKPEHVKAWLLRKAGTSVAIPERCMIAEKDLVIDIECCLEDTVLIKSIFEEAWEDKSVALFIPGTSIKGVLRHYCSRILQALGRSNQAVDALFGYSIEKTNESRKGRVMVDEVYFDKSFTQEEQPRIRVDRFTGGAMNGALFQDHPVRKGKGKELVFPLRMTVKDCSDSEAGLVLLLVKDLMTGQITLGANRTIGYGRIKGNSVAVQYHGESYGIDGTGKVTEGESTKLEALVQALHQSTEDTMLAKEGAHE
>NZ_CP019721.1|WP_077707845.1|543337_544918_-|hypothetical-protein
MEQVNITITVKSPTLIANSSTAGVLTSTRGSIDGRVLRGLFASQFISSHKLGREAHKNQDFMNLFYGDLRFVAAYKHTPKGTSFPAPLSLQKNKNAEGYASDDVVDFYTGKDLLGFKGVKGFVIVDGKECSPVQIETAIKLHMSRSLEQERVQGRSNEGRNIFNYEYIEPNQVFVGSVVGPKAALEEFVRQFPKQLDCHIGRSRRTEYGHCIVEIGDITAVPTPVNSGNSIYVRLHTPLVLGNESIGHVVAQAVQSIGSDISVGTVFASYQEEQSFNSIWGVRSSAEASASAGSIVELVKESGWSQDDLDKLQNILYNGMGTRLQEGYGQGRLWTPGEFKMVKLGKQEAPKLKSLHTLTQEIAKKVLEKQVIVNARLRAAHDVDTYIKRTMSRSGISKHFASVLLTELGTNHETGHKQLQQFLEDKKAEGQKKNEPRVIEKNLREFHLGHAYTRSETKRVNLMEYIIDFDAPTLVAACLAKSGESGTYYEIPAELVDMVGLDKQKLSNVVAYEYWTYFFRHIRKIK
>NZ_CP019721.1|WP_077707846.1|544905_545553_-|CRISPR-associated-protein
MYTLTIKLLSPTMLMSGQGDVNTDSTIVHDRYGIPFIPAKRVRGVLYESAIEVAEMMHAAGLNTFTIDDVKVLFNRLEGAEDNPRLSISNLTIADYDVVASELAALEEQYPAVFTKERVLEEYTSMRYYTSIDQVTGTALEGTLHNSRVLNRALAFSGQIDVEDMTEIERLILACAVRNLTGIGGKRNRGFGQVECTIDDASFDLESLGGTLWNK

Crispr_ID: NZ_CP019721_5

• CRISPR_ID: NZ_CP019721_5
• CRISPR_location: 549989-551458
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 19 spacers
• Cas_protein_info: cas2,cas1,csx20,cas10,csm3gr7,csx10gr5,csx19,csx1,cas6

Consensus repeat of NZ_CP019721_5

Consensus_repeat	Method
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	CRISPRCasFinder
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	CRT
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	PILER-CR

spacers of NZ_CP019721_5

>5.1|550024|39|NZ_CP019721|CRISPRCasFinder
TATCGCGAAATTCGCTAGTGATAAACGTGTGCAACCGAT
>5.2|550098|87|NZ_CP019721|CRISPRCasFinder
TCACCCTTGTTTTACCTTCACTTCGTTCAGGTACTTGAGATGTGCGGACCTCATCGTCGCTTTGCTCCTCTGCTGTCTCGCACCCTT
>5.3|550220|38|NZ_CP019721|CRISPRCasFinder,CRT
AAGGTGGAAGGCGTCGATGTATACCGTCCGGTTTTCAA
>5.4|550293|38|NZ_CP019721|CRISPRCasFinder,CRT
AAGGTGGAAGGCGTCGATGTATACCGTCCGGTTTTCAA
>5.5|550366|40|NZ_CP019721|CRISPRCasFinder,CRT
TCCCAAATCATTCTGAAACACCATGATAAAGATAGTAATC
>5.6|550441|40|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
CAGAACGTAGCGATTTATTAGTACCAGCTGAAGTTGTGCG
>5.7|550516|34|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
TTCAAGAAGAATGGAACGCTACTGATTTAATTGA
>5.8|550585|38|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
GATATGGATACGATGTATGTAGATAAAGAACGCTATAG
>5.9|550658|36|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
ATAATTCTCATCGGTGAGACTCTCCATTGAATATAG
>5.10|550729|38|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
AAAAAAGATTTAGAATATTTAATACAAGAAAATAAGCG
>5.11|550802|39|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
AATTAAAATAAAGAGAAAGGGTGAACTGTCTTGTGCACT
>5.12|550876|40|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
TTTGTGCTATTGCACAATTAGTTTTAGGTAGTTATTTCTC
>5.13|550951|36|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
ATGAACAAAAAGATCGAAAAGATGACTTTAGATTTT
>5.14|551022|37|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
ACTGATGTAGAAGACATCGAAGTTGGTTATATTCAAG
>5.15|551094|39|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
GATAGAAAACTTTCAACATACAACATCGATATTTTTTAA
>5.16|551168|36|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
TAGTCATATGACCATATGTATCACGGCGTTGAATAC
>5.17|551239|36|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
CCTCATTTAATTAATTAAAATTATTTTATTTTGGCA
>5.18|551310|41|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
CACCGATGCCGATAGATTTAGTTGCGTTTGCCAAGATGCCA
>5.19|551386|37|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
TGCAACATCTCGTTCTATTAAACCAGGCGAGAAGGTA

CRISPR arrays and Neighbor proteins around NZ_CP019721_5

CRISPR arrays

The CRISPR arrays of NZ_CP019721_5

>merge|NZ_CP019721|5|549989-551458|CRISPRCasFinder,CRT,PILER-CR
CTGCGCATACCGTAAACGGTAAGCACTGTTGCAACTATCGCGAAATTCGCTAGTGATAAACGTGTGCAACCGATGTTTCAATACCGTAAACGGTAAGCTGAATCCCTTATCACCCTTGTTTTACCTTCACTTCGTTCAGGTACTTGAGATGTGCGGACCTCATCGTCGCTTTGCTCCTCTGCTGTCTCGCACCCTTCTGCGCATACCGTAAACGGTAAGAGCTGTTGCAACAAGGTGGAAGGCGTCGATGTATACCGTCCGGTTTTCAAGTTTCAATACCGTAAACGGTAAGAGCTGTTGCAACAAGGTGGAAGGCGTCGATGTATACCGTCCGGTTTTCAAGTTTCAATACCGTAAACGGTAAGAGCTGTTGCAACTCCCAAATCATTCTGAAACACCATGATAAAGATAGTAATCGTTTCAATACCGTAAACGGTAAGAGCTGTTGCAACCAGAACGTAGCGATTTATTAGTACCAGCTGAAGTTGTGCGGTTTCAATACCGTAAACGGTAAGAGCTGTTGCAACTTCAAGAAGAATGGAACGCTACTGATTTAATTGAGTTTCAATACCGTAAACGGTAAGAGCTGTTGCAACGATATGGATACGATGTATGTAGATAAAGAACGCTATAGGTTTCAATACCGTAAACGGTAAGAGCTGTTGCAACATAATTCTCATCGGTGAGACTCTCCATTGAATATAGGTTTCAATACCGTAAACGGTAAGAGCTGTTGCAACAAAAAAGATTTAGAATATTTAATACAAGAAAATAAGCGGTTTCAATACCGTAAACGGTAAGAGCTGTTGCAACAATTAAAATAAAGAGAAAGGGTGAACTGTCTTGTGCACTGTTTCAATACCGTAAACGGTAAGAGCTGTTGCAACTTTGTGCTATTGCACAATTAGTTTTAGGTAGTTATTTCTCGTTTCAATACCGTAAACGGTAAGAGCTGTTGCAACATGAACAAAAAGATCGAAAAGATGACTTTAGATTTTGTTTCAATACCGTAAACGGTAAGAGCTGTTGCAACACTGATGTAGAAGACATCGAAGTTGGTTATATTCAAGGTTTCAATACCGTAAACGGTAAGAGCTGTTGCAACGATAGAAAACTTTCAACATACAACATCGATATTTTTTAAGTTTCAATACCGTAAACGGTAAGAGCTGTTGCAACTAGTCATATGACCATATGTATCACGGCGTTGAATACGTTTCAATACCGTAAACGGTAAGAGCTGTTGCAACCCTCATTTAATTAATTAAAATTATTTTATTTTGGCAGTTTCAATACCGTAAACGGTAAGAGCTGTTGCAACCACCGATGCCGATAGATTTAGTTGCGTTTGCCAAGATGCCAGTTTCAATACCGTAAACGGTAAGAGCTGTTGCAACTGCAACATCTCGTTCTATTAAACCAGGCGAGAAGGTAGTTTCAATACCGTAAACGGTAAGAGCTGTTGCAACA

>NZ_CP019721|5|4|549989-551458|CRISPRCasFinder
CTGCGCATACCGTAAACGGTAAGCACTGTTGCAAC	TATCGCGAAATTCGCTAGTGATAAACGTGTGCAACCGAT
GTTTCAATACCGTAAACGGTAAGCTGAATCCCTTA	TCACCCTTGTTTTACCTTCACTTCGTTCAGGTACTTGAGATGTGCGGACCTCATCGTCGCTTTGCTCCTCTGCTGTCTCGCACCCTT
CTGCGCATACCGTAAACGGTAAGAGCTGTTGCAAC	AAGGTGGAAGGCGTCGATGTATACCGTCCGGTTTTCAA
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	AAGGTGGAAGGCGTCGATGTATACCGTCCGGTTTTCAA
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	TCCCAAATCATTCTGAAACACCATGATAAAGATAGTAATC
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	CAGAACGTAGCGATTTATTAGTACCAGCTGAAGTTGTGCG
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	TTCAAGAAGAATGGAACGCTACTGATTTAATTGA
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	GATATGGATACGATGTATGTAGATAAAGAACGCTATAG
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	ATAATTCTCATCGGTGAGACTCTCCATTGAATATAG
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	AAAAAAGATTTAGAATATTTAATACAAGAAAATAAGCG
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	AATTAAAATAAAGAGAAAGGGTGAACTGTCTTGTGCACT
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	TTTGTGCTATTGCACAATTAGTTTTAGGTAGTTATTTCTC
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	ATGAACAAAAAGATCGAAAAGATGACTTTAGATTTT
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	ACTGATGTAGAAGACATCGAAGTTGGTTATATTCAAG
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	GATAGAAAACTTTCAACATACAACATCGATATTTTTTAA
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	TAGTCATATGACCATATGTATCACGGCGTTGAATAC
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	CCTCATTTAATTAATTAAAATTATTTTATTTTGGCA
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	CACCGATGCCGATAGATTTAGTTGCGTTTGCCAAGATGCCA
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	TGCAACATCTCGTTCTATTAAACCAGGCGAGAAGGTA
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAACA

>NZ_CP019721|5|3|550185-551457|CRT
CTGCGCATACCGTAAACGGTAAGAGCTGTTGCAAC	AAGGTGGAAGGCGTCGATGTATACCGTCCGGTTTTCAA
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	AAGGTGGAAGGCGTCGATGTATACCGTCCGGTTTTCAA
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	TCCCAAATCATTCTGAAACACCATGATAAAGATAGTAATC
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	CAGAACGTAGCGATTTATTAGTACCAGCTGAAGTTGTGCG
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	TTCAAGAAGAATGGAACGCTACTGATTTAATTGA
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	GATATGGATACGATGTATGTAGATAAAGAACGCTATAG
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	ATAATTCTCATCGGTGAGACTCTCCATTGAATATAG
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	AAAAAAGATTTAGAATATTTAATACAAGAAAATAAGCG
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	AATTAAAATAAAGAGAAAGGGTGAACTGTCTTGTGCACT
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	TTTGTGCTATTGCACAATTAGTTTTAGGTAGTTATTTCTC
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	ATGAACAAAAAGATCGAAAAGATGACTTTAGATTTT
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	ACTGATGTAGAAGACATCGAAGTTGGTTATATTCAAG
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	GATAGAAAACTTTCAACATACAACATCGATATTTTTTAA
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	TAGTCATATGACCATATGTATCACGGCGTTGAATAC
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	CCTCATTTAATTAATTAAAATTATTTTATTTTGGCA
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	CACCGATGCCGATAGATTTAGTTGCGTTTGCCAAGATGCCA
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	TGCAACATCTCGTTCTATTAAACCAGGCGAGAAGGTA
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC

>NZ_CP019721|5|3|550406-551457|PILER-CR
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	CAGAACGTAGCGATTTATTAGTACCAGCTGAAGTTGTGCG
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	TTCAAGAAGAATGGAACGCTACTGATTTAATTGA
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	GATATGGATACGATGTATGTAGATAAAGAACGCTATAG
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	ATAATTCTCATCGGTGAGACTCTCCATTGAATATAG
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	AAAAAAGATTTAGAATATTTAATACAAGAAAATAAGCG
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	AATTAAAATAAAGAGAAAGGGTGAACTGTCTTGTGCACT
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	TTTGTGCTATTGCACAATTAGTTTTAGGTAGTTATTTCTC
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	ATGAACAAAAAGATCGAAAAGATGACTTTAGATTTT
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	ACTGATGTAGAAGACATCGAAGTTGGTTATATTCAAG
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	GATAGAAAACTTTCAACATACAACATCGATATTTTTTAA
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	TAGTCATATGACCATATGTATCACGGCGTTGAATAC
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	CCTCATTTAATTAATTAAAATTATTTTATTTTGGCA
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	CACCGATGCCGATAGATTTAGTTGCGTTTGCCAAGATGCCA
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	TGCAACATCTCGTTCTATTAAACCAGGCGAGAAGGTA
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019721.1|WP_077707855.1|570256_571405_-|glycosyl-hydrolase-family-3	unknown	unknown	gnl|CDD|366376
NZ_CP019721.1|WP_077707850.1|555023_557042_+|hypothetical-protein	csx1	cd09732_csx1_CAS-III	unknown
NZ_CP019721.1|WP_077707842.1|539422_541432_-|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|274902
NZ_CP019721.1|WP_077708641.1|557102_559247_-|TM1812-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	gnl|CDD|378186
NZ_CP019721.1|WP_077707849.1|549148_549568_-|DUF805-domain-containing-protein	unknown	unknown	gnl|CDD|377540
NZ_CP019721.1|WP_077707853.1|566631_567240_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707843.1|541433_541997_-|TIGR03984-family-CRISPR-associated-protein	csx19	cls001376_csx19_CAS-III-D	gnl|CDD|274900
NZ_CP019721.1|WP_077707844.1|541989_543324_-|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl|CDD|187857
NZ_CP019721.1|WP_077707852.1|563955_564726_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	gnl|CDD|273848
NZ_CP019721.1|WP_077707848.1|547745_548744_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|376633
NZ_CP019721.1|WP_077707846.1|544905_545553_-|CRISPR-associated-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|377130
NZ_CP019721.1|WP_008601954.1|548758_549037_-|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|378256
NZ_CP019721.1|WP_077707856.1|571818_573249_-|iron-hydrogenase-small-subunit	unknown	unknown	gnl|CDD|274171
NZ_CP019721.1|WP_077707854.1|567559_568426_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NZ_CP019721.1|WP_077707845.1|543337_544918_-|hypothetical-protein	csx10gr5	cls000715_csx10gr5_CAS-III-D	unknown
NZ_CP019721.1|WP_077707851.1|559388_561785_+|hypothetical-protein	unknown	unknown	gnl|CDD|379100
NZ_CP019721.1|WP_008601959.1|547187_547553_-|hypothetical-protein	csx20	cls000118_csx20_CAS-I:CAS-III	unknown
NZ_CP019721.1|WP_187658829.1|552642_552843_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_004694443.1|568716_569781_-|ATP-binding-protein	unknown	unknown	gnl|CDD|379062
NZ_CP019721.1|WP_077707847.1|545555_547157_-|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	gnl|CDD|274209

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP019721.1|WP_077707850.1|555023_557042_+|hypothetical-protein	csx1	cd09732_csx1_CAS-III	3.4e-11	37.9	0.1
NZ_CP019721.1|WP_077707842.1|539422_541432_-|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	1.7e-156	517.6	0.7
NZ_CP019721.1|WP_077708641.1|557102_559247_-|TM1812-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	4.2e-12	40.9	4.9
NZ_CP019721.1|WP_077707843.1|541433_541997_-|TIGR03984-family-CRISPR-associated-protein	csx19	cls001376_csx19_CAS-III-D	1.4e-49	163.0	0.2
NZ_CP019721.1|WP_077707844.1|541989_543324_-|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	1.6e-34	114.6	0.0
NZ_CP019721.1|WP_077707852.1|563955_564726_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	7.3e-17	56.8	0.1
NZ_CP019721.1|WP_077707848.1|547745_548744_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	7.2e-75	246.6	0.0
NZ_CP019721.1|WP_077707846.1|544905_545553_-|CRISPR-associated-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	9.6e-38	124.4	0.0
NZ_CP019721.1|WP_008601954.1|548758_549037_-|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	1e-18	62.2	0.4
NZ_CP019721.1|WP_077707845.1|543337_544918_-|hypothetical-protein	csx10gr5	cls000715_csx10gr5_CAS-III-D	9.6e-13	42.7	0.8
NZ_CP019721.1|WP_008601959.1|547187_547553_-|hypothetical-protein	csx20	cls000118_csx20_CAS-I:CAS-III	1.1e-58	192.0	0.0
NZ_CP019721.1|WP_077707847.1|545555_547157_-|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	9.6e-79	260.0	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP019721.1|WP_077707852.1|563955_564726_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl|CDD|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	0.000585577
NZ_CP019721.1|WP_077707842.1|539422_541432_-|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl|CDD|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	8.61432e-150
NZ_CP019721.1|WP_077708641.1|557102_559247_-|TM1812-family-CRISPR-associated-protein	gnl|CDD|378186	pfam09455, Cas_DxTHG, CRISPR-associated (Cas) DxTHG family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. The family describes Cas proteins of about 400 residues that include the motif [VIL]-D-x-[ST]-H-[GS]. The CRISPR and associated proteins are thought to be involved in the evolution of host resistance. The exact molecular function of this family is currently unknown.	0.00192657
NZ_CP019721.1|WP_077707849.1|549148_549568_-|DUF805-domain-containing-protein	gnl|CDD|377540	pfam05656, DUF805, Protein of unknown function (DUF805). This family consists of several bacterial proteins of unknown function.	6.22624e-10
NZ_CP019721.1|WP_077707843.1|541433_541997_-|TIGR03984-family-CRISPR-associated-protein	gnl|CDD|274900	TIGR03984, hypothetical_protein_FrEUN1fDRAFT_5778, CRISPR-associated protein, TIGR03984 family. Members of this protein family are found exclusively in CRISPR-containing organisms, in operon contexts with RAMP (repeat-associated mystery protein) proteins also linked to CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats).	4.04648e-46
NZ_CP019721.1|WP_077707844.1|541989_543324_-|CRISPR-associated-protein	gnl|CDD|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	2.90366e-15
NZ_CP019721.1|WP_077707855.1|570256_571405_-|glycosyl-hydrolase-family-3	gnl|CDD|366376	pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain.	4.47107e-31
NZ_CP019721.1|WP_077707848.1|547745_548744_-|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	4.40622e-95
NZ_CP019721.1|WP_077707846.1|544905_545553_-|CRISPR-associated-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.49345e-12
NZ_CP019721.1|WP_008601954.1|548758_549037_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	3.83589e-14
NZ_CP019721.1|WP_077707856.1|571818_573249_-|iron-hydrogenase-small-subunit	gnl|CDD|274171	TIGR02512, Periplasmic_hydrogenase_large_subunit, [FeFe] hydrogenase, group A. This model describes iron-only hydrogenases of anaerobic and microaerophilic bacteria and protozoa. This model is narrower, and covers a longer stretch of sequence, than pfam02906. This family represents a division among families that belong to pfam02906, which also includes proteins such as nuclear prelamin A recognition factor in animals. Note that this family shows some heterogeneity in terms of periplasmic, cytosolic, or hydrogenosome location, NAD or NADP dependence, and overal protein protein length.	0
NZ_CP019721.1|WP_077707854.1|567559_568426_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	3.18865e-14
NZ_CP019721.1|WP_077707851.1|559388_561785_+|hypothetical-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	0.00177802
NZ_CP019721.1|WP_004694443.1|568716_569781_-|ATP-binding-protein	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	3.42348e-06
NZ_CP019721.1|WP_077707847.1|545555_547157_-|hypothetical-protein	gnl|CDD|274209	TIGR02578, CRISPR-associated_protein_Cas10/Csm1, CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2. A typical example is TM1811 from Thermotoga maritima. CRISPR are Clustered Regularly Interspaced Short Palindromic Repeats. This protein family belongs to a conserved gene cluster regularly found near CRISPR repeats.	3.09865e-05

Protein sequences

>NZ_CP019721.1|WP_077707849.1|549148_549568_-|DUF805-domain-containing-protein
MIIKEGIMENLQQELKSMLSLSGRMNRRSYFMNLLMIIGIGYLGGLCISLAPVSKFFWVLGWSIIGYSVVRELAIASRRIHDLNGPTYLAGIYIVAAIIAIFEPTLAKIMGFVKIGLVLMPGDEDPNNYGERPDSMIVV
>NZ_CP019721.1|WP_008601954.1|548758_549037_-|CRISPR-associated-endonuclease-Cas2
MMRYLISYDISDTKIRNKVVKYLESFCYRVQYSVFLCVHAHVRVETIAKKLEVLTQGDETRRLLIVSISDTAKTPIWCNKMIPLTEDKMLII
>NZ_CP019721.1|WP_077707848.1|547745_548744_-|CRISPR-associated-endonuclease-Cas1
MMLETLYVMTPGISIRQDGGLLVLEKDHSVIKEIPIATVSNLVLGRTIQISTQVMFSLVKQGSLIQFVDHKYQLVGTLGDEHTTLQRLLWQVACFQNQEFALDGAKYIVRRKIKGQIALLNQYKKSKCIPNFVVVHRTMQALLKRVERTKKVDTLRGIEGLASRTYFSVLGHVLSEPWEFSGRKRHPSPDPVNAILSYGYSFLEREVRACLLTAGLDVRIGVLHSTNNRKDSLVYDVMDIFRQDIIDRFVLKLLNRHMMLPEDFDLSERGCFLSKETNKKWVELYEDYMKAELSRLDNLAPRKWIQQEIQAFISYLKSLGETVDIEKSENIS
>NZ_CP019721.1|WP_008601959.1|547187_547553_-|hypothetical-protein
MFINHTNHPSQYWSDEQLAAAHQYGEVVDIPFPLIDPALPSGEIGQLVQEYAGRIISLNPQAVLCQGEFVYCHALVERLLAVGITVLVATSERLVSESYEAGINEKIVNFQFVQFREYCHL
>NZ_CP019721.1|WP_077707847.1|545555_547157_-|hypothetical-protein
MQVNAILFDVQSIQKYIFANNKLKANVGASFIVDRLFEDVLCKEIINKLGVEADTTSWLTRSDSITSLPKTIYVAYIGGGNALVLIDDKHESLVQDIVKKFTTQVLVQYPGLKVGATTGYITLDGTQFSADLGKLYKQLKANQFALNPIVHPANTGLTTICDFSGDVADTTQSFGDEKRLVATSFTAKFEAFEAANSRLKIDLFGTETTDWVFPSEFEELGQNQSTEKSKTGINDIAIVHIDGNNMGAHFRQCKTLEERSALSKRVATKTLESFKALVQWIIDKYDILDENLELSKNMLPIRPIIIGGDDITFICNARIAVQASHYLMQQLLSDKNGISISSCAGIAVIPTSYPFFRGYEMAEQLCDSAKSKMREYNAVHKVNESCWMDFAFLHGETAPTLEQFFANEYSSLTGNMHFGPYQVFNDNIEAEKDIFALSKLLECTNQFILVKDKAYSGDLLAHNKVKELRSVLQDNEHMWTVFLEQLRNTNKFMPTVSGWDAFKEKLWAKVNGKMRTPYVDAIELMDYVLPGLE
>NZ_CP019721.1|WP_077707846.1|544905_545553_-|CRISPR-associated-protein
MYTLTIKLLSPTMLMSGQGDVNTDSTIVHDRYGIPFIPAKRVRGVLYESAIEVAEMMHAAGLNTFTIDDVKVLFNRLEGAEDNPRLSISNLTIADYDVVASELAALEEQYPAVFTKERVLEEYTSMRYYTSIDQVTGTALEGTLHNSRVLNRALAFSGQIDVEDMTEIERLILACAVRNLTGIGGKRNRGFGQVECTIDDASFDLESLGGTLWNK
>NZ_CP019721.1|WP_077707845.1|543337_544918_-|hypothetical-protein
MEQVNITITVKSPTLIANSSTAGVLTSTRGSIDGRVLRGLFASQFISSHKLGREAHKNQDFMNLFYGDLRFVAAYKHTPKGTSFPAPLSLQKNKNAEGYASDDVVDFYTGKDLLGFKGVKGFVIVDGKECSPVQIETAIKLHMSRSLEQERVQGRSNEGRNIFNYEYIEPNQVFVGSVVGPKAALEEFVRQFPKQLDCHIGRSRRTEYGHCIVEIGDITAVPTPVNSGNSIYVRLHTPLVLGNESIGHVVAQAVQSIGSDISVGTVFASYQEEQSFNSIWGVRSSAEASASAGSIVELVKESGWSQDDLDKLQNILYNGMGTRLQEGYGQGRLWTPGEFKMVKLGKQEAPKLKSLHTLTQEIAKKVLEKQVIVNARLRAAHDVDTYIKRTMSRSGISKHFASVLLTELGTNHETGHKQLQQFLEDKKAEGQKKNEPRVIEKNLREFHLGHAYTRSETKRVNLMEYIIDFDAPTLVAACLAKSGESGTYYEIPAELVDMVGLDKQKLSNVVAYEYWTYFFRHIRKIK
>NZ_CP019721.1|WP_077707844.1|541989_543324_-|CRISPR-associated-protein
MLNSASVIGRYTLTGTVKLTSPLVIRAGVSNDILNDTVDDIVVTYHDGQPFIPGTSLAGVLRQAIQGLEPVSEDVLFGSIDDKGTQSALQINDIPLDNTNIVVRDGICIDDVRGVTKDGAKYDFEVIESGATGRLRIDCVIRQCHENQVDKIERALVALANLLKNGISVGARTVNGLGRIACKDISLEHYDFTKPEHVKAWLLRKAGTSVAIPERCMIAEKDLVIDIECCLEDTVLIKSIFEEAWEDKSVALFIPGTSIKGVLRHYCSRILQALGRSNQAVDALFGYSIEKTNESRKGRVMVDEVYFDKSFTQEEQPRIRVDRFTGGAMNGALFQDHPVRKGKGKELVFPLRMTVKDCSDSEAGLVLLLVKDLMTGQITLGANRTIGYGRIKGNSVAVQYHGESYGIDGTGKVTEGESTKLEALVQALHQSTEDTMLAKEGAHE
>NZ_CP019721.1|WP_077707843.1|541433_541997_-|TIGR03984-family-CRISPR-associated-protein
MSKQLHSYEGVYTRTCGICGPTANVNVLAVAKEQMKQEGLVITWSVHEVKWGYYKQGGFQFSDGTTDVDLAYLQDMRIFNEMEELRLTVQHGEVVYRYINDEAGKAVIYVDSSSRMIGEVDAGRTQLNRVESFTSLIDTGRKLSQIIPVSTTKQYCYLTTRNYIGYLDNHQASYTDYRYVKIEAKEV
>NZ_CP019721.1|WP_077707842.1|539422_541432_-|TIGR03986-family-CRISPR-associated-RAMP-protein
MAGKGKSKNRHAASEAFFARNNPGMDVEKVANERHYGGNRGGQNRSGGYNNSYNNQGGNRSGGNSKYPSEPASAAYNFVRLPEHVIPAEFYNGHFEGVTKDVLKAYCDHVQQADTHTGYIDLTITTETPLFIGGPSKQDEDTPLEFYGGQDNPTIPGASLKGMVKEIFKIVTASSFRPYQRGTGLGDFEDRYLYFRDFASSIKSLKEYYASRMVGMEKNGKGEMKAATKATPGFIIQTVDNNYFAVPSESRKMSYSGDYEMQKKKDTPSIDWNDQYVNIHTGRMNSKKSYMRITRPGNFEGKRIPILQECIDSYKDDKNRGTLNLLDKKVGKSGDAAKNYTRCDDVKFVVPCFFSEKDGIVEHFGHGRFYRIAYDLKISDHLPTTLEQHNNGVDLCDSVFGYGDNWAGRLSFSDAHVVGPVRMCQSDYPHPLMGPNPTSFQLYLEQDVDNHSTYNHWGHEGASIRGYKMYWHQPLAKAKDWTRTEAEKAIQGTRKIRPVDTGVTFKSRIHFERLSSVELGALLMSLDLDHYSGGNRRTYYKLGMGKSIGFGSIKLESAVTVFDSKERYGSLFGGNTWNTGASITTPNEYVESFTQYRDNALGSNISSYKAMLDDLFMMLDWNIANGPNAAKNWTEGISMMTIKNNKMDPRIKYRSKLDTPKSFIAKWSK
>NZ_CP019721.1|WP_187658829.1|552642_552843_-|hypothetical-protein
MQQYLLFTVLKQPDGPGFFESIILLQQYLPFTVCAEGCETAEEQSDDEVRTSQVPERSEGKTKVTK
>NZ_CP019721.1|WP_077707850.1|555023_557042_+|hypothetical-protein
MEHHIYLTFLSTLHTKNNPYNPQKLEKTVVNLTEIAPFNVIRQTNESALKYLLHNKRKENSTFKLDKLFFFKSPEMENTFKESTISSLNVFEEQMCDYINKTSIPITWSPETINYIDCGDIDYIDNLKDSIIDMSQAIMEYYKSKSSDDRVILHVDLSGGPRTAIMLMIAIIRLVAFQGIEIGSILYANVNANNNSIVRVYEGNSIYNIYDMITGFAEFNQFGSVDTLKNYVNTLDNPDVQIKELISSMGDFSEAVRLSSRGIFQRSMEDIHKLLTDIESSKQEIPANNRENHKNFEIEALKLMSGKIQNNYKTVLANKEDDLAYIDWCLDNGYLQQALALFAEFVPRAILESKMIILDDTIFPTDSDNELSASMENFNTINEYTAKTMEIVNNRATKINNKIKSVLLKYFSGDFSKESKRIIKEVLKDKKNNTSTNITREDTQYPKFEEQLINDINQIILKEAEKEPHNYLKYKTFTNNNVNVPSKLLRLISNIGINTKSIVGINEFSKDIRRYFTAALVHQLKEIKDLPSDVVTVNDQYEITLNDTNKLFKVRDAFISIFTNSNNDDIYRFLFANFVSYQYPIDLFPHQLYGIDGLTLNSVLKSNPEKITQVARILNLYRTLKGSRNDTAHAREEKRGQFIESEDIKRELKQCLNDIRKVREYICTYNQQ
>NZ_CP019721.1|WP_077708641.1|557102_559247_-|TM1812-family-CRISPR-associated-protein
MAIHNIFLSFLSKVSNTSIKTIVNTDIEDAIRSSIATNESSLKYILYHTWKDEKTRDISFDKIYLLCTDGVMAHQSNSPSSYDIFVNQMCKFYNVMGHNEQAFFDALDHVPCGTDLDDISRIKSSIIEMSKKILDFKDTFTNDKDEVRLYMDITGGPRNAAMILLVISRLLAYHGIIVDDVYYSGYKEIENGPGEITVHKVLDIYELFDIIAGFEEFKLFGSAKKLNTYFKSPENIGTGNIESTATATKKLLKAMDSFSEAINISSRGAFEKSIARLDDSLSLVHSMANNTDNNKTFDQELIELLHKPIEQSYTTLLQHHRNHASDELAYIDWCLDHDYLQQALTLFCEYVPEYAVDKGIIKCDSLVFNAYYEDTQQNKEKRLLQAAIKAWNRAGNNIHFSTFYNVVMPDHDKKTSEKDARSMPMRLFNSINNARMQYLAAMINAKKDEVAPNIDKVITYYIKFVRNEKKKIQIVERDLQKQKERIHLMVDEETTKLREKCEVLLNQYGFTLYLQDDRYAENYTLLEYILFLQDILESVENIEAFNNILESLRKNIISEVLSKEEFKEYIICDADNSSFRLKKTSMLARNVVCNAILNHLIEEKKYKAYKSLIMHQLPDTKDSAVTAAELLLSQKKSNHRGVPLFEVSGVYIPHVLLDDIAKTMKFIEQYFEIKKARNDSNHANKEVLCKYTTSQELLDEMRKCVAMARELSRK
>NZ_CP019721.1|WP_077707851.1|559388_561785_+|hypothetical-protein
MYIFKRESIMATTTNYLNDLASMRQFIRSLTFGNHNRGKATVRGIKESQHDDVIRRLDYFDIIRHIYTQRIGKTSIHHLAKDDFVDGYNYLNNLYELYAAVPEQIYVQLCILSYIGANDDVTITDLYTNLNQEPYLDHYIDLVENLYEQRNKKQEPPCIIDQQYIQRQVKTLEILGAITKTELTKGYTYSIKPTIIEELSKQQLQELAMAVFFYTNVSITSAAGHILLKKIMYLINDFSLKDQQKCMYYDFNNTYFSFKDNNPNNVIDGDIFYPLADALHRQKKVRLSFYESGKPREIVSPLALQTYYGENKNMLCSINNGRIQWNRIDRIKSLEVTKYNSTNTVPQIQTKDKTFDTCIIHFLTLKDYDLVYDKFIRHFKESLTVLSSTDEYIELQLEVQDALQLLPQLRSYLPYVYITYTNKSSIKDKFYNNLYASLNIDFVEPEGYKKRKKINRFLHPLQRKESDNNKTKKDKDLDGTYVSSVLNDINAITFTTQYQLQLDLINGVVHTKQDIEGLINHRRLLTPAPYKKVLRNDDYEQFLADALVEPNENGEEVESILPDLPLVIISDAERMFLKDLISDTRANWLLSPELCQILSTELETVDTTFPRGSWTRVPTMTDDTPLTMQVITQCLQAIQNNERIMIQDKELSPCRIEYSVGSNGYTLIAYDHATDTFLDYPLRNESNIIKTAAPRLEDIETIYANYRDESKRTVTFTLYDANNAVDRCFNYFSNYTIQAKDINDEEFTIEVSYLPFQEIDILRHLLKLGCAVRITDDSPLKKQLETIYKTALIHAPSI
>NZ_CP019721.1|WP_077707852.1|563955_564726_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MSDNVEIMSIELVIVADLSIKIVQSIGSVLHGVLMELVGTEYAGQLHETGLRPYSQYIYFDKHKKQYIWRLSAVTADAVNRIVRPTLEMPEKIFLKQKRGYLYIKDRTILEETSYEALIHKFWSSDAFYSQTKLQCMSTTSFKVDQQYTIFPEAFRIYRYLLRQWNHFSTFGTMDADSLIDTFEKGVFIRDYNLRMGIYSLEGIKIRGFRGQIVMQFKRNIELQKILALLSYYSQFTGLGIKTALGMGGVKCEIIE
>NZ_CP019721.1|WP_077707853.1|566631_567240_-|hypothetical-protein
MAIDDKPTDLMAARLSKGEDLDLIYTNPKNHIVCFIPTYQPSGGDSTKCYFVDGREEMVHLPMRTITRELAMQEGLRPNYIMTSDGRRSSYTAPKTYGPHLTFAHIKCRRPIGKDVVYGLFNVAIPYEYIVTEGPEPDTSYIHVADFAPILVYQSPRHVKHKLNEAMLEHCNYVRKMLARIKLSQNPQVVAELFIAWRDLTR
>NZ_CP019721.1|WP_077707854.1|567559_568426_-|sigma-70-family-RNA-polymerase-sigma-factor
MLYTNEEPLVQKICIKTANLQHDNYQSETLETQALPSHSLLSKADESTRSIPEELKLQTLVCGHQVLSSLSDKSLVSICQKPNMRIQTVGYQPWSVDELRHDAAQIELCRRYRPLILHYTNRMGNREFREDVESYLWAILIESIYSFDLNGTVPFPGFVKAGIMYGYMRYWKRERLRYHREIHIPDRTTDDGEVAFGMDIFASGENVADMVMSADEEHRLRARLVWALGRLSPDQRDLLRRVYGECQSLVSVSEELNCSRQAIQRRHERAIRKLRRYLSTDFKDVRVH
>NZ_CP019721.1|WP_004694443.1|568716_569781_-|ATP-binding-protein
MNFVGRAEIIERIQSRIAMGQMSLCVVYGPHRSGKSYVASQLVRRHKAIYLAGRMANESVHVADINRALEARFVPANAQDTFEPVESLQQAFVRLFESSVKTPQTVVIDDYPSLVEAVPQFPIHLRDLLDTYKDTSRLNIILMANGLEQLDGRIIGDRSLIGPFVSEYLEVKPFSLVDMKSLGLHYAKDDLRTVFAVTGGLPAYVQYFDNGESIDTNIINLFFSVTGALFEETQYILHRDMKNITGANAILTGLASLERPYYVELLQESQIKSGTFTSRLNDLMSMGLVGRIQASNRGNAKYADYHFTNSMFHFWYRYVYKYWGDIVRGYGADVYYNHVKPQLKDFVQAACIAI
>NZ_CP019721.1|WP_077707855.1|570256_571405_-|glycosyl-hydrolase-family-3
MNQFFRRVLSGLALLVAVVGTTGCQHESQAEQETVRTVSYRAVLESNKPVSEKVDTWIAAMSQEDKVGQLMMISLHGSTIGQSQKDVIRKYRVSGVMLTNENLINKNQVKTFTSDIMQTAITSSMVTPYIAVYRDRILHGNESFLRLPKPNRWGQLPMDRIINLATRSAIEMRDMGFNLVIGPNANLGVPNMSYTSDPTWAGHINLAMVERYQINHMWSAYNYFPAVTLGDASFGSANEAKAYLSNNDVAVFKRLIAQTTANSYMLVMSHIQIPAIDNEHLASSSKPIIDGWLRKELGYKGIVMTDRIDVGALQSNQKIGDYAVASILAGSDLILVDADTIHIDEVHRALTQAVADGTITTERLNESVKRILLMKMQTQMDP
>NZ_CP019721.1|WP_077707856.1|571818_573249_-|iron-hydrogenase-small-subunit
MSQYEFIDKRVPIALDNPSIYHDISKCKNCTLCRRACADVMSVLDYYDLDANGDVPVCIHCGQCAAACPFDSMHAKSELEKVKAALADPEKIVVIQTAPAVRVSIGEGFGYEPGTFLEGKMVGALRKLGADYVVDTNFGADLTIMEEASELVERLKNGGQIPQFTSCCPAWVRFAEIYFPELIPNLSSTRSCIAMEAAMIKTYFAEKKGIDPRNIVSVSVNPCTAKKAETKREEENAAARYHNDESLGMDTDISITTREFIRWIQEEHIDFNTVEESQFDDLIGMETGASIIFGNTGGVMEAALRTAYKLITDKEPPPYALTHLEDVRGMEGVKEATVQLGDDVTLSVAVVHGGKNTRDFLNALKDSGKHYDFIEVMACPGGCIGGGGQPRTKLPQAVKTKEARIGGLYEADENYKWVASYENEEIQTLYKDFLGEPLGHKAHELLHTHYTDRSAVLGTRKDVTPETCPTSPKFKG

Crispr_ID: NZ_CP019721_6

• CRISPR_ID: NZ_CP019721_6
• CRISPR_location: 552738-554211
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 19 spacers
• Cas_protein_info: cas2,cas1,csx20,cas10,csm3gr7,csx10gr5,csx19,csx1,cas6

Consensus repeat of NZ_CP019721_6

Consensus_repeat	Method
GTTTCAATACCGTAAACGGTAAGAGCTGTTGCAAC	CRISPRCasFinder
GTTTCAATACCGTAAACGGTANGTACTGTTGCAAC	CRT
AGTTTCAATACCGTAAACGGTAAGTACTGTTGCAACT	PILER-CR
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	CRT
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	PILER-CR

spacers of NZ_CP019721_6

>6.1|552773|37|NZ_CP019721|CRISPRCasFinder,CRT
AATATAATACTTTCGAAGAATCCCGGCCCATCTGGCT
>6.2|552845|38|NZ_CP019721|CRISPRCasFinder,CRT
CTTGCCGCAATGCAAGCACAGAATGCAATGCTTATGGA
>6.3|552918|37|NZ_CP019721|CRISPRCasFinder,CRT
TCGAAGAAGTTCGTGAAATCTTCGGGAAAGGAGTAAA
>6.4|552990|41|NZ_CP019721|CRISPRCasFinder,CRT
TTTAATACATTGCAATATGCAGTATTGGTATGCATGATTGC
>6.5|553066|87|NZ_CP019721|CRISPRCasFinder
TCACCTTCGTTTTACCTTCACTTCGTTCAGGTACTTGAGATGTGCGGACCTCATCGTCGCTTTGCGCCTCTGCTGTCTCGCACCCTT
>6.6|553188|40|NZ_CP019721|CRISPRCasFinder,CRT
TAACATTACTCATATTATTGAGTTTATCGAAAGGAATAAA
>6.7|553263|37|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
GAAGTTTTGATGAAGCCATGGTTCTTAAGGTTGGTAA
>6.8|553335|38|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
GAAAGAGTACACTAATTATTTGTTCATTAGTCGTGTCC
>6.9|553408|35|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
GCGATAGATAGGTACTGCTACCTTATCGCCTGGTT
>6.10|553478|37|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
TTAAATAATACATCGTCTACTATAACTTCACCACAGA
>6.11|553550|37|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
CTTATTACTAAGAGTCTTCGTTAATCCATGGTATTAG
>6.12|553622|38|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
TTTACCATTAGCAGATGAAAACATTTGCAATGGTACAG
>6.13|553695|39|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
TTCCTAGGATGTCAATACATACCCATTGAGGTATATCGA
>6.14|553769|35|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
GAGATGCTGTGTCAGAGATGGTATCTAAATCTAAA
>6.15|553839|43|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
AGCACAAAAATTGAATACTTATGTAGGTTTGTTTGCTGCACCA
>6.16|553917|41|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
TCAGTGGTTTTATATGTACTGGTAGTGAACTTTTCAAGATG
>6.17|553993|38|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
TACCTAAAAAATCAGCAAATTTGTTTATAGTTCCATAG
>6.18|554066|39|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
TTGTTTTGAATATGTATAAAGAGGGTAAATAAAATGAGA
>6.19|554140|37|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR
AATTTAAGAACAGGATCTACTTCTGCAGTAGCCATAA
>6.20|552847|36|NZ_CP019721|PILER-CR
TTGCCGCAATGCAAGCACAGAATGCAATGCTTATGG
>6.21|552920|35|NZ_CP019721|PILER-CR
CGAAGAAGTTCGTGAAATCTTCGGGAAAGGAGTAA

CRISPR arrays and Neighbor proteins around NZ_CP019721_6

CRISPR arrays

The CRISPR arrays of NZ_CP019721_6

>merge|NZ_CP019721|6|552738-554211|CRISPRCasFinder,CRT,PILER-CR,CRT,PILER-CR
CGGCGCATACCGTAAACGGTAAGTACTGTTGCAACAATATAATACTTTCGAAGAATCCCGGCCCATCTGGCTGTTTCAACACCGTAAACAGTAAGTACTGTTGCAACCTTGCCGCAATGCAAGCACAGAATGCAATGCTTATGGAGTTTCAATACCGTAAACGGTAAGTACTGTTGCAACTCGAAGAAGTTCGTGAAATCTTCGGGAAAGGAGTAAAGTTTCAATACCGTAAACGGTAGGTACTGTTGCAACTTTAATACATTGCAATATGCAGTATTGGTATGCATGATTGCGTTTCAATACCGTAAACGGTAGGCTGAATCCCTTATCACCTTCGTTTTACCTTCACTTCGTTCAGGTACTTGAGATGTGCGGACCTCATCGTCGCTTTGCGCCTCTGCTGTCTCGCACCCTTCGGCGCATACCGTAAACGGTAAGTACTGTTGCAACTAACATTACTCATATTATTGAGTTTATCGAAAGGAATAAAGTTTCAATACCGTAAACGGTAAGTACTGTTGCAACGAAGTTTTGATGAAGCCATGGTTCTTAAGGTTGGTAAGTTTCAATACCGTAAACGGTAAGTACTGTTGCAACGAAAGAGTACACTAATTATTTGTTCATTAGTCGTGTCCGTTTCAATACCGTAAACGGTAAGTACTGTTGCAACGCGATAGATAGGTACTGCTACCTTATCGCCTGGTTGTTTCAATACCGTAAACGGTAAGTACTGTTGCAACTTAAATAATACATCGTCTACTATAACTTCACCACAGAGTTTCAATACCGTAAACGGTAAGTACTGTTGCAACCTTATTACTAAGAGTCTTCGTTAATCCATGGTATTAGGTTTCAATACCGTAAACGGTAAGTACTGTTGCAACTTTACCATTAGCAGATGAAAACATTTGCAATGGTACAGGTTTCAATACCGTAAACGGTAAGTACTGTTGCAACTTCCTAGGATGTCAATACATACCCATTGAGGTATATCGAGTTTCAATACCGTAAACGGTAAGTACTGTTGCAACGAGATGCTGTGTCAGAGATGGTATCTAAATCTAAAGTTTCAATACCGTAAACGGTAAGTACTGTTGCAACAGCACAAAAATTGAATACTTATGTAGGTTTGTTTGCTGCACCAGTTTCAATACCGTAAACGGTAAGTACTGTTGCAACTCAGTGGTTTTATATGTACTGGTAGTGAACTTTTCAAGATGGTTTCAATACCGTAAACGGTAAGTACTGTTGCAACTACCTAAAAAATCAGCAAATTTGTTTATAGTTCCATAGGTTTCAATACCGTAAACGGTAAGTACTGTTGCAACTTGTTTTGAATATGTATAAAGAGGGTAAATAAAATGAGAGTTTCAATACCGTAAACGGTAAGTACTGTTGCAACAATTTAAGAACAGGATCTACTTCTGCAGTAGCCATAAGTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC

>NZ_CP019721|6|5|552738-554211|CRISPRCasFinder
CGGCGCATACCGTAAACGGTAAGTACTGTTGCAAC	AATATAATACTTTCGAAGAATCCCGGCCCATCTGGCT
GTTTCAACACCGTAAACAGTAAGTACTGTTGCAAC	CTTGCCGCAATGCAAGCACAGAATGCAATGCTTATGGA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TCGAAGAAGTTCGTGAAATCTTCGGGAAAGGAGTAAA
GTTTCAATACCGTAAACGGTAGGTACTGTTGCAAC	TTTAATACATTGCAATATGCAGTATTGGTATGCATGATTGC
GTTTCAATACCGTAAACGGTAGGCTGAATCCCTTA	TCACCTTCGTTTTACCTTCACTTCGTTCAGGTACTTGAGATGTGCGGACCTCATCGTCGCTTTGCGCCTCTGCTGTCTCGCACCCTT
CGGCGCATACCGTAAACGGTAAGTACTGTTGCAAC	TAACATTACTCATATTATTGAGTTTATCGAAAGGAATAAA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GAAGTTTTGATGAAGCCATGGTTCTTAAGGTTGGTAA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GAAAGAGTACACTAATTATTTGTTCATTAGTCGTGTCC
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GCGATAGATAGGTACTGCTACCTTATCGCCTGGTT
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TTAAATAATACATCGTCTACTATAACTTCACCACAGA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	CTTATTACTAAGAGTCTTCGTTAATCCATGGTATTAG
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TTTACCATTAGCAGATGAAAACATTTGCAATGGTACAG
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TTCCTAGGATGTCAATACATACCCATTGAGGTATATCGA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GAGATGCTGTGTCAGAGATGGTATCTAAATCTAAA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	AGCACAAAAATTGAATACTTATGTAGGTTTGTTTGCTGCACCA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TCAGTGGTTTTATATGTACTGGTAGTGAACTTTTCAAGATG
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TACCTAAAAAATCAGCAAATTTGTTTATAGTTCCATAG
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TTGTTTTGAATATGTATAAAGAGGGTAAATAAAATGAGA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	AATTTAAGAACAGGATCTACTTCTGCAGTAGCCATAA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC

>NZ_CP019721|6|4|552738-553065|CRT
CGGCGCATACCGTAAACGGTAAGTACTGTTGCAAC	AATATAATACTTTCGAAGAATCCCGGCCCATCTGGCT
GTTTCAACACCGTAAACAGTAAGTACTGTTGCAAC	CTTGCCGCAATGCAAGCACAGAATGCAATGCTTATGGA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TCGAAGAAGTTCGTGAAATCTTCGGGAAAGGAGTAAA
GTTTCAATACCGTAAACGGTAGGTACTGTTGCAAC	TTTAATACATTGCAATATGCAGTATTGGTATGCATGATTGC
GTTTCAATACCGTAAACGGTAGGCTGAATCCCTTATCACCTTCGTTTTACCTTCACTTCGTTCAGGTACTTGAGATGTGCGGACCTCATCGTCGCTTTGCGCCTCTGCTGTCTCGCACCCTTCGGCGCATACCGTAAACGGTAAGTACTGTTGCAAC	TAACATTACTCATATTATTGAGTTTATCGAAAGGAATAAA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GAAGTTTTGATGAAGCCATGGTTCTTAAGGTTGGTAA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GAAAGAGTACACTAATTATTTGTTCATTAGTCGTGTCC
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GCGATAGATAGGTACTGCTACCTTATCGCCTGGTT
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TTAAATAATACATCGTCTACTATAACTTCACCACAGA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	CTTATTACTAAGAGTCTTCGTTAATCCATGGTATTAG
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TTTACCATTAGCAGATGAAAACATTTGCAATGGTACAG
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TTCCTAGGATGTCAATACATACCCATTGAGGTATATCGA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GAGATGCTGTGTCAGAGATGGTATCTAAATCTAAA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	AGCACAAAAATTGAATACTTATGTAGGTTTGTTTGCTGCACCA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TCAGTGGTTTTATATGTACTGGTAGTGAACTTTTCAAGATG
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TACCTAAAAAATCAGCAAATTTGTTTATAGTTCCATAG
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TTGTTTTGAATATGTATAAAGAGGGTAAATAAAATGAGA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	AATTTAAGAACAGGATCTACTTCTGCAGTAGCCATAA


>NZ_CP019721|6|4|552810-552990|PILER-CR
GTTTCAACACCGTAAACAGTAAGTACTGTTGCAACCT	TGCCGCAATGCAAGCACAGAATGCAATGCTTATGGA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAACTC	GAAGAAGTTCGTGAAATCTTCGGGAAAGGAGTAAA
GTTTCAATACCGTAAACGGTAGGTACTGTTGCAACTTTAATACATTGCAATATGCAGTATTGGTATGCATGATTGCGTTTCAATACCGTAAACGGTAGGCTGAATCCCTTATCACCTTCGTTTTACCTTCACTTCGTTCAGGTACTTGAGATGTGCGGACCTCATCGTCGCTTTGCGCCTCTGCTGTCTCGCACCCTTCGGCGCATACCGTAAACGGTAAGTACTGTTGCAACTAACATTACTCATATTATTGAGTTTATCGAAAGGAATAAAGTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GAAGTTTTGATGAAGCCATGGTTCTTAAGGTTGGTAA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GAAAGAGTACACTAATTATTTGTTCATTAGTCGTGTCC
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GCGATAGATAGGTACTGCTACCTTATCGCCTGGTT
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TTAAATAATACATCGTCTACTATAACTTCACCACAGA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	CTTATTACTAAGAGTCTTCGTTAATCCATGGTATTAG
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TTTACCATTAGCAGATGAAAACATTTGCAATGGTACAG
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TTCCTAGGATGTCAATACATACCCATTGAGGTATATCGA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GAGATGCTGTGTCAGAGATGGTATCTAAATCTAAA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	AGCACAAAAATTGAATACTTATGTAGGTTTGTTTGCTGCACCA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TCAGTGGTTTTATATGTACTGGTAGTGAACTTTTCAAGATG
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TACCTAAAAAATCAGCAAATTTGTTTATAGTTCCATAG
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TTGTTTTGAATATGTATAAAGAGGGTAAATAAAATGAGA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	AATTTAAGAACAGGATCTACTTCTGCAGTAGCCATAA


>NZ_CP019721|6|5|553153-554211|CRT
	AATATAATACTTTCGAAGAATCCCGGCCCATCTGGCT
GTTTCAACACCGTAAACAGTAAGTACTGTTGCAAC	CTTGCCGCAATGCAAGCACAGAATGCAATGCTTATGGA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TCGAAGAAGTTCGTGAAATCTTCGGGAAAGGAGTAAA
GTTTCAATACCGTAAACGGTAGGTACTGTTGCAAC	TTTAATACATTGCAATATGCAGTATTGGTATGCATGATTGC
GTTTCAATACCGTAAACGGTAGGCTGAATCCCTTATCACCTTCGTTTTACCTTCACTTCGTTCAGGTACTTGAGATGTGCGGACCTCATCGTCGCTTTGCGCCTCTGCTGTCTCGCACCCTTCGGCGCATACCGTAAACGGTAAGTACTGTTGCAAC	TAACATTACTCATATTATTGAGTTTATCGAAAGGAATAAA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GAAGTTTTGATGAAGCCATGGTTCTTAAGGTTGGTAA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GAAAGAGTACACTAATTATTTGTTCATTAGTCGTGTCC
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GCGATAGATAGGTACTGCTACCTTATCGCCTGGTT
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TTAAATAATACATCGTCTACTATAACTTCACCACAGA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	CTTATTACTAAGAGTCTTCGTTAATCCATGGTATTAG
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TTTACCATTAGCAGATGAAAACATTTGCAATGGTACAG
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TTCCTAGGATGTCAATACATACCCATTGAGGTATATCGA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GAGATGCTGTGTCAGAGATGGTATCTAAATCTAAA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	AGCACAAAAATTGAATACTTATGTAGGTTTGTTTGCTGCACCA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TCAGTGGTTTTATATGTACTGGTAGTGAACTTTTCAAGATG
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TACCTAAAAAATCAGCAAATTTGTTTATAGTTCCATAG
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TTGTTTTGAATATGTATAAAGAGGGTAAATAAAATGAGA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	AATTTAAGAACAGGATCTACTTCTGCAGTAGCCATAA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC

>NZ_CP019721|6|5|553228-554211|PILER-CR
	TGCCGCAATGCAAGCACAGAATGCAATGCTTATGGA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAACTC	GAAGAAGTTCGTGAAATCTTCGGGAAAGGAGTAAA
GTTTCAATACCGTAAACGGTAGGTACTGTTGCAACTTTAATACATTGCAATATGCAGTATTGGTATGCATGATTGCGTTTCAATACCGTAAACGGTAGGCTGAATCCCTTATCACCTTCGTTTTACCTTCACTTCGTTCAGGTACTTGAGATGTGCGGACCTCATCGTCGCTTTGCGCCTCTGCTGTCTCGCACCCTTCGGCGCATACCGTAAACGGTAAGTACTGTTGCAACTAACATTACTCATATTATTGAGTTTATCGAAAGGAATAAAGTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GAAGTTTTGATGAAGCCATGGTTCTTAAGGTTGGTAA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GAAAGAGTACACTAATTATTTGTTCATTAGTCGTGTCC
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GCGATAGATAGGTACTGCTACCTTATCGCCTGGTT
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TTAAATAATACATCGTCTACTATAACTTCACCACAGA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	CTTATTACTAAGAGTCTTCGTTAATCCATGGTATTAG
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TTTACCATTAGCAGATGAAAACATTTGCAATGGTACAG
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TTCCTAGGATGTCAATACATACCCATTGAGGTATATCGA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GAGATGCTGTGTCAGAGATGGTATCTAAATCTAAA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	AGCACAAAAATTGAATACTTATGTAGGTTTGTTTGCTGCACCA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TCAGTGGTTTTATATGTACTGGTAGTGAACTTTTCAAGATG
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TACCTAAAAAATCAGCAAATTTGTTTATAGTTCCATAG
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	TTGTTTTGAATATGTATAAAGAGGGTAAATAAAATGAGA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	AATTTAAGAACAGGATCTACTTCTGCAGTAGCCATAA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019721.1|WP_077707855.1|570256_571405_-|glycosyl-hydrolase-family-3	unknown	unknown	gnl|CDD|366376
NZ_CP019721.1|WP_077707850.1|555023_557042_+|hypothetical-protein	csx1	cd09732_csx1_CAS-III	unknown
NZ_CP019721.1|WP_077707842.1|539422_541432_-|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|274902
NZ_CP019721.1|WP_077708641.1|557102_559247_-|TM1812-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	gnl|CDD|378186
NZ_CP019721.1|WP_077707849.1|549148_549568_-|DUF805-domain-containing-protein	unknown	unknown	gnl|CDD|377540
NZ_CP019721.1|WP_077707853.1|566631_567240_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707843.1|541433_541997_-|TIGR03984-family-CRISPR-associated-protein	csx19	cls001376_csx19_CAS-III-D	gnl|CDD|274900
NZ_CP019721.1|WP_077707844.1|541989_543324_-|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl|CDD|187857
NZ_CP019721.1|WP_077707852.1|563955_564726_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	gnl|CDD|273848
NZ_CP019721.1|WP_077707848.1|547745_548744_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|376633
NZ_CP019721.1|WP_077707846.1|544905_545553_-|CRISPR-associated-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|377130
NZ_CP019721.1|WP_008601954.1|548758_549037_-|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|378256
NZ_CP019721.1|WP_077707856.1|571818_573249_-|iron-hydrogenase-small-subunit	unknown	unknown	gnl|CDD|274171
NZ_CP019721.1|WP_077707854.1|567559_568426_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NZ_CP019721.1|WP_077707845.1|543337_544918_-|hypothetical-protein	csx10gr5	cls000715_csx10gr5_CAS-III-D	unknown
NZ_CP019721.1|WP_077707851.1|559388_561785_+|hypothetical-protein	unknown	unknown	gnl|CDD|379100
NZ_CP019721.1|WP_008601959.1|547187_547553_-|hypothetical-protein	csx20	cls000118_csx20_CAS-I:CAS-III	unknown
NZ_CP019721.1|WP_004694437.1|573572_573947_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_004694443.1|568716_569781_-|ATP-binding-protein	unknown	unknown	gnl|CDD|379062
NZ_CP019721.1|WP_077707847.1|545555_547157_-|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	gnl|CDD|274209

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP019721.1|WP_077707850.1|555023_557042_+|hypothetical-protein	csx1	cd09732_csx1_CAS-III	3.4e-11	37.9	0.1
NZ_CP019721.1|WP_077707842.1|539422_541432_-|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	1.7e-156	517.6	0.7
NZ_CP019721.1|WP_077708641.1|557102_559247_-|TM1812-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	4.2e-12	40.9	4.9
NZ_CP019721.1|WP_077707843.1|541433_541997_-|TIGR03984-family-CRISPR-associated-protein	csx19	cls001376_csx19_CAS-III-D	1.4e-49	163.0	0.2
NZ_CP019721.1|WP_077707844.1|541989_543324_-|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	1.6e-34	114.6	0.0
NZ_CP019721.1|WP_077707852.1|563955_564726_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	7.3e-17	56.8	0.1
NZ_CP019721.1|WP_077707848.1|547745_548744_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	7.2e-75	246.6	0.0
NZ_CP019721.1|WP_077707846.1|544905_545553_-|CRISPR-associated-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	9.6e-38	124.4	0.0
NZ_CP019721.1|WP_008601954.1|548758_549037_-|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	1e-18	62.2	0.4
NZ_CP019721.1|WP_077707845.1|543337_544918_-|hypothetical-protein	csx10gr5	cls000715_csx10gr5_CAS-III-D	9.6e-13	42.7	0.8
NZ_CP019721.1|WP_008601959.1|547187_547553_-|hypothetical-protein	csx20	cls000118_csx20_CAS-I:CAS-III	1.1e-58	192.0	0.0
NZ_CP019721.1|WP_077707847.1|545555_547157_-|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	9.6e-79	260.0	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP019721.1|WP_077707852.1|563955_564726_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl|CDD|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	0.000585577
NZ_CP019721.1|WP_077707842.1|539422_541432_-|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl|CDD|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	8.61432e-150
NZ_CP019721.1|WP_077708641.1|557102_559247_-|TM1812-family-CRISPR-associated-protein	gnl|CDD|378186	pfam09455, Cas_DxTHG, CRISPR-associated (Cas) DxTHG family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. The family describes Cas proteins of about 400 residues that include the motif [VIL]-D-x-[ST]-H-[GS]. The CRISPR and associated proteins are thought to be involved in the evolution of host resistance. The exact molecular function of this family is currently unknown.	0.00192657
NZ_CP019721.1|WP_077707849.1|549148_549568_-|DUF805-domain-containing-protein	gnl|CDD|377540	pfam05656, DUF805, Protein of unknown function (DUF805). This family consists of several bacterial proteins of unknown function.	6.22624e-10
NZ_CP019721.1|WP_077707843.1|541433_541997_-|TIGR03984-family-CRISPR-associated-protein	gnl|CDD|274900	TIGR03984, hypothetical_protein_FrEUN1fDRAFT_5778, CRISPR-associated protein, TIGR03984 family. Members of this protein family are found exclusively in CRISPR-containing organisms, in operon contexts with RAMP (repeat-associated mystery protein) proteins also linked to CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats).	4.04648e-46
NZ_CP019721.1|WP_077707844.1|541989_543324_-|CRISPR-associated-protein	gnl|CDD|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	2.90366e-15
NZ_CP019721.1|WP_077707855.1|570256_571405_-|glycosyl-hydrolase-family-3	gnl|CDD|366376	pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain.	4.47107e-31
NZ_CP019721.1|WP_077707848.1|547745_548744_-|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	4.40622e-95
NZ_CP019721.1|WP_077707846.1|544905_545553_-|CRISPR-associated-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.49345e-12
NZ_CP019721.1|WP_008601954.1|548758_549037_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	3.83589e-14
NZ_CP019721.1|WP_077707856.1|571818_573249_-|iron-hydrogenase-small-subunit	gnl|CDD|274171	TIGR02512, Periplasmic_hydrogenase_large_subunit, [FeFe] hydrogenase, group A. This model describes iron-only hydrogenases of anaerobic and microaerophilic bacteria and protozoa. This model is narrower, and covers a longer stretch of sequence, than pfam02906. This family represents a division among families that belong to pfam02906, which also includes proteins such as nuclear prelamin A recognition factor in animals. Note that this family shows some heterogeneity in terms of periplasmic, cytosolic, or hydrogenosome location, NAD or NADP dependence, and overal protein protein length.	0
NZ_CP019721.1|WP_077707854.1|567559_568426_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	3.18865e-14
NZ_CP019721.1|WP_077707851.1|559388_561785_+|hypothetical-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	0.00177802
NZ_CP019721.1|WP_004694443.1|568716_569781_-|ATP-binding-protein	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	3.42348e-06
NZ_CP019721.1|WP_077707847.1|545555_547157_-|hypothetical-protein	gnl|CDD|274209	TIGR02578, CRISPR-associated_protein_Cas10/Csm1, CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2. A typical example is TM1811 from Thermotoga maritima. CRISPR are Clustered Regularly Interspaced Short Palindromic Repeats. This protein family belongs to a conserved gene cluster regularly found near CRISPR repeats.	3.09865e-05

Protein sequences

>NZ_CP019721.1|WP_077707849.1|549148_549568_-|DUF805-domain-containing-protein
MIIKEGIMENLQQELKSMLSLSGRMNRRSYFMNLLMIIGIGYLGGLCISLAPVSKFFWVLGWSIIGYSVVRELAIASRRIHDLNGPTYLAGIYIVAAIIAIFEPTLAKIMGFVKIGLVLMPGDEDPNNYGERPDSMIVV
>NZ_CP019721.1|WP_008601954.1|548758_549037_-|CRISPR-associated-endonuclease-Cas2
MMRYLISYDISDTKIRNKVVKYLESFCYRVQYSVFLCVHAHVRVETIAKKLEVLTQGDETRRLLIVSISDTAKTPIWCNKMIPLTEDKMLII
>NZ_CP019721.1|WP_077707848.1|547745_548744_-|CRISPR-associated-endonuclease-Cas1
MMLETLYVMTPGISIRQDGGLLVLEKDHSVIKEIPIATVSNLVLGRTIQISTQVMFSLVKQGSLIQFVDHKYQLVGTLGDEHTTLQRLLWQVACFQNQEFALDGAKYIVRRKIKGQIALLNQYKKSKCIPNFVVVHRTMQALLKRVERTKKVDTLRGIEGLASRTYFSVLGHVLSEPWEFSGRKRHPSPDPVNAILSYGYSFLEREVRACLLTAGLDVRIGVLHSTNNRKDSLVYDVMDIFRQDIIDRFVLKLLNRHMMLPEDFDLSERGCFLSKETNKKWVELYEDYMKAELSRLDNLAPRKWIQQEIQAFISYLKSLGETVDIEKSENIS
>NZ_CP019721.1|WP_008601959.1|547187_547553_-|hypothetical-protein
MFINHTNHPSQYWSDEQLAAAHQYGEVVDIPFPLIDPALPSGEIGQLVQEYAGRIISLNPQAVLCQGEFVYCHALVERLLAVGITVLVATSERLVSESYEAGINEKIVNFQFVQFREYCHL
>NZ_CP019721.1|WP_077707847.1|545555_547157_-|hypothetical-protein
MQVNAILFDVQSIQKYIFANNKLKANVGASFIVDRLFEDVLCKEIINKLGVEADTTSWLTRSDSITSLPKTIYVAYIGGGNALVLIDDKHESLVQDIVKKFTTQVLVQYPGLKVGATTGYITLDGTQFSADLGKLYKQLKANQFALNPIVHPANTGLTTICDFSGDVADTTQSFGDEKRLVATSFTAKFEAFEAANSRLKIDLFGTETTDWVFPSEFEELGQNQSTEKSKTGINDIAIVHIDGNNMGAHFRQCKTLEERSALSKRVATKTLESFKALVQWIIDKYDILDENLELSKNMLPIRPIIIGGDDITFICNARIAVQASHYLMQQLLSDKNGISISSCAGIAVIPTSYPFFRGYEMAEQLCDSAKSKMREYNAVHKVNESCWMDFAFLHGETAPTLEQFFANEYSSLTGNMHFGPYQVFNDNIEAEKDIFALSKLLECTNQFILVKDKAYSGDLLAHNKVKELRSVLQDNEHMWTVFLEQLRNTNKFMPTVSGWDAFKEKLWAKVNGKMRTPYVDAIELMDYVLPGLE
>NZ_CP019721.1|WP_077707846.1|544905_545553_-|CRISPR-associated-protein
MYTLTIKLLSPTMLMSGQGDVNTDSTIVHDRYGIPFIPAKRVRGVLYESAIEVAEMMHAAGLNTFTIDDVKVLFNRLEGAEDNPRLSISNLTIADYDVVASELAALEEQYPAVFTKERVLEEYTSMRYYTSIDQVTGTALEGTLHNSRVLNRALAFSGQIDVEDMTEIERLILACAVRNLTGIGGKRNRGFGQVECTIDDASFDLESLGGTLWNK
>NZ_CP019721.1|WP_077707845.1|543337_544918_-|hypothetical-protein
MEQVNITITVKSPTLIANSSTAGVLTSTRGSIDGRVLRGLFASQFISSHKLGREAHKNQDFMNLFYGDLRFVAAYKHTPKGTSFPAPLSLQKNKNAEGYASDDVVDFYTGKDLLGFKGVKGFVIVDGKECSPVQIETAIKLHMSRSLEQERVQGRSNEGRNIFNYEYIEPNQVFVGSVVGPKAALEEFVRQFPKQLDCHIGRSRRTEYGHCIVEIGDITAVPTPVNSGNSIYVRLHTPLVLGNESIGHVVAQAVQSIGSDISVGTVFASYQEEQSFNSIWGVRSSAEASASAGSIVELVKESGWSQDDLDKLQNILYNGMGTRLQEGYGQGRLWTPGEFKMVKLGKQEAPKLKSLHTLTQEIAKKVLEKQVIVNARLRAAHDVDTYIKRTMSRSGISKHFASVLLTELGTNHETGHKQLQQFLEDKKAEGQKKNEPRVIEKNLREFHLGHAYTRSETKRVNLMEYIIDFDAPTLVAACLAKSGESGTYYEIPAELVDMVGLDKQKLSNVVAYEYWTYFFRHIRKIK
>NZ_CP019721.1|WP_077707844.1|541989_543324_-|CRISPR-associated-protein
MLNSASVIGRYTLTGTVKLTSPLVIRAGVSNDILNDTVDDIVVTYHDGQPFIPGTSLAGVLRQAIQGLEPVSEDVLFGSIDDKGTQSALQINDIPLDNTNIVVRDGICIDDVRGVTKDGAKYDFEVIESGATGRLRIDCVIRQCHENQVDKIERALVALANLLKNGISVGARTVNGLGRIACKDISLEHYDFTKPEHVKAWLLRKAGTSVAIPERCMIAEKDLVIDIECCLEDTVLIKSIFEEAWEDKSVALFIPGTSIKGVLRHYCSRILQALGRSNQAVDALFGYSIEKTNESRKGRVMVDEVYFDKSFTQEEQPRIRVDRFTGGAMNGALFQDHPVRKGKGKELVFPLRMTVKDCSDSEAGLVLLLVKDLMTGQITLGANRTIGYGRIKGNSVAVQYHGESYGIDGTGKVTEGESTKLEALVQALHQSTEDTMLAKEGAHE
>NZ_CP019721.1|WP_077707843.1|541433_541997_-|TIGR03984-family-CRISPR-associated-protein
MSKQLHSYEGVYTRTCGICGPTANVNVLAVAKEQMKQEGLVITWSVHEVKWGYYKQGGFQFSDGTTDVDLAYLQDMRIFNEMEELRLTVQHGEVVYRYINDEAGKAVIYVDSSSRMIGEVDAGRTQLNRVESFTSLIDTGRKLSQIIPVSTTKQYCYLTTRNYIGYLDNHQASYTDYRYVKIEAKEV
>NZ_CP019721.1|WP_077707842.1|539422_541432_-|TIGR03986-family-CRISPR-associated-RAMP-protein
MAGKGKSKNRHAASEAFFARNNPGMDVEKVANERHYGGNRGGQNRSGGYNNSYNNQGGNRSGGNSKYPSEPASAAYNFVRLPEHVIPAEFYNGHFEGVTKDVLKAYCDHVQQADTHTGYIDLTITTETPLFIGGPSKQDEDTPLEFYGGQDNPTIPGASLKGMVKEIFKIVTASSFRPYQRGTGLGDFEDRYLYFRDFASSIKSLKEYYASRMVGMEKNGKGEMKAATKATPGFIIQTVDNNYFAVPSESRKMSYSGDYEMQKKKDTPSIDWNDQYVNIHTGRMNSKKSYMRITRPGNFEGKRIPILQECIDSYKDDKNRGTLNLLDKKVGKSGDAAKNYTRCDDVKFVVPCFFSEKDGIVEHFGHGRFYRIAYDLKISDHLPTTLEQHNNGVDLCDSVFGYGDNWAGRLSFSDAHVVGPVRMCQSDYPHPLMGPNPTSFQLYLEQDVDNHSTYNHWGHEGASIRGYKMYWHQPLAKAKDWTRTEAEKAIQGTRKIRPVDTGVTFKSRIHFERLSSVELGALLMSLDLDHYSGGNRRTYYKLGMGKSIGFGSIKLESAVTVFDSKERYGSLFGGNTWNTGASITTPNEYVESFTQYRDNALGSNISSYKAMLDDLFMMLDWNIANGPNAAKNWTEGISMMTIKNNKMDPRIKYRSKLDTPKSFIAKWSK
>NZ_CP019721.1|WP_077707850.1|555023_557042_+|hypothetical-protein
MEHHIYLTFLSTLHTKNNPYNPQKLEKTVVNLTEIAPFNVIRQTNESALKYLLHNKRKENSTFKLDKLFFFKSPEMENTFKESTISSLNVFEEQMCDYINKTSIPITWSPETINYIDCGDIDYIDNLKDSIIDMSQAIMEYYKSKSSDDRVILHVDLSGGPRTAIMLMIAIIRLVAFQGIEIGSILYANVNANNNSIVRVYEGNSIYNIYDMITGFAEFNQFGSVDTLKNYVNTLDNPDVQIKELISSMGDFSEAVRLSSRGIFQRSMEDIHKLLTDIESSKQEIPANNRENHKNFEIEALKLMSGKIQNNYKTVLANKEDDLAYIDWCLDNGYLQQALALFAEFVPRAILESKMIILDDTIFPTDSDNELSASMENFNTINEYTAKTMEIVNNRATKINNKIKSVLLKYFSGDFSKESKRIIKEVLKDKKNNTSTNITREDTQYPKFEEQLINDINQIILKEAEKEPHNYLKYKTFTNNNVNVPSKLLRLISNIGINTKSIVGINEFSKDIRRYFTAALVHQLKEIKDLPSDVVTVNDQYEITLNDTNKLFKVRDAFISIFTNSNNDDIYRFLFANFVSYQYPIDLFPHQLYGIDGLTLNSVLKSNPEKITQVARILNLYRTLKGSRNDTAHAREEKRGQFIESEDIKRELKQCLNDIRKVREYICTYNQQ
>NZ_CP019721.1|WP_077708641.1|557102_559247_-|TM1812-family-CRISPR-associated-protein
MAIHNIFLSFLSKVSNTSIKTIVNTDIEDAIRSSIATNESSLKYILYHTWKDEKTRDISFDKIYLLCTDGVMAHQSNSPSSYDIFVNQMCKFYNVMGHNEQAFFDALDHVPCGTDLDDISRIKSSIIEMSKKILDFKDTFTNDKDEVRLYMDITGGPRNAAMILLVISRLLAYHGIIVDDVYYSGYKEIENGPGEITVHKVLDIYELFDIIAGFEEFKLFGSAKKLNTYFKSPENIGTGNIESTATATKKLLKAMDSFSEAINISSRGAFEKSIARLDDSLSLVHSMANNTDNNKTFDQELIELLHKPIEQSYTTLLQHHRNHASDELAYIDWCLDHDYLQQALTLFCEYVPEYAVDKGIIKCDSLVFNAYYEDTQQNKEKRLLQAAIKAWNRAGNNIHFSTFYNVVMPDHDKKTSEKDARSMPMRLFNSINNARMQYLAAMINAKKDEVAPNIDKVITYYIKFVRNEKKKIQIVERDLQKQKERIHLMVDEETTKLREKCEVLLNQYGFTLYLQDDRYAENYTLLEYILFLQDILESVENIEAFNNILESLRKNIISEVLSKEEFKEYIICDADNSSFRLKKTSMLARNVVCNAILNHLIEEKKYKAYKSLIMHQLPDTKDSAVTAAELLLSQKKSNHRGVPLFEVSGVYIPHVLLDDIAKTMKFIEQYFEIKKARNDSNHANKEVLCKYTTSQELLDEMRKCVAMARELSRK
>NZ_CP019721.1|WP_077707851.1|559388_561785_+|hypothetical-protein
MYIFKRESIMATTTNYLNDLASMRQFIRSLTFGNHNRGKATVRGIKESQHDDVIRRLDYFDIIRHIYTQRIGKTSIHHLAKDDFVDGYNYLNNLYELYAAVPEQIYVQLCILSYIGANDDVTITDLYTNLNQEPYLDHYIDLVENLYEQRNKKQEPPCIIDQQYIQRQVKTLEILGAITKTELTKGYTYSIKPTIIEELSKQQLQELAMAVFFYTNVSITSAAGHILLKKIMYLINDFSLKDQQKCMYYDFNNTYFSFKDNNPNNVIDGDIFYPLADALHRQKKVRLSFYESGKPREIVSPLALQTYYGENKNMLCSINNGRIQWNRIDRIKSLEVTKYNSTNTVPQIQTKDKTFDTCIIHFLTLKDYDLVYDKFIRHFKESLTVLSSTDEYIELQLEVQDALQLLPQLRSYLPYVYITYTNKSSIKDKFYNNLYASLNIDFVEPEGYKKRKKINRFLHPLQRKESDNNKTKKDKDLDGTYVSSVLNDINAITFTTQYQLQLDLINGVVHTKQDIEGLINHRRLLTPAPYKKVLRNDDYEQFLADALVEPNENGEEVESILPDLPLVIISDAERMFLKDLISDTRANWLLSPELCQILSTELETVDTTFPRGSWTRVPTMTDDTPLTMQVITQCLQAIQNNERIMIQDKELSPCRIEYSVGSNGYTLIAYDHATDTFLDYPLRNESNIIKTAAPRLEDIETIYANYRDESKRTVTFTLYDANNAVDRCFNYFSNYTIQAKDINDEEFTIEVSYLPFQEIDILRHLLKLGCAVRITDDSPLKKQLETIYKTALIHAPSI
>NZ_CP019721.1|WP_077707852.1|563955_564726_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MSDNVEIMSIELVIVADLSIKIVQSIGSVLHGVLMELVGTEYAGQLHETGLRPYSQYIYFDKHKKQYIWRLSAVTADAVNRIVRPTLEMPEKIFLKQKRGYLYIKDRTILEETSYEALIHKFWSSDAFYSQTKLQCMSTTSFKVDQQYTIFPEAFRIYRYLLRQWNHFSTFGTMDADSLIDTFEKGVFIRDYNLRMGIYSLEGIKIRGFRGQIVMQFKRNIELQKILALLSYYSQFTGLGIKTALGMGGVKCEIIE
>NZ_CP019721.1|WP_077707853.1|566631_567240_-|hypothetical-protein
MAIDDKPTDLMAARLSKGEDLDLIYTNPKNHIVCFIPTYQPSGGDSTKCYFVDGREEMVHLPMRTITRELAMQEGLRPNYIMTSDGRRSSYTAPKTYGPHLTFAHIKCRRPIGKDVVYGLFNVAIPYEYIVTEGPEPDTSYIHVADFAPILVYQSPRHVKHKLNEAMLEHCNYVRKMLARIKLSQNPQVVAELFIAWRDLTR
>NZ_CP019721.1|WP_077707854.1|567559_568426_-|sigma-70-family-RNA-polymerase-sigma-factor
MLYTNEEPLVQKICIKTANLQHDNYQSETLETQALPSHSLLSKADESTRSIPEELKLQTLVCGHQVLSSLSDKSLVSICQKPNMRIQTVGYQPWSVDELRHDAAQIELCRRYRPLILHYTNRMGNREFREDVESYLWAILIESIYSFDLNGTVPFPGFVKAGIMYGYMRYWKRERLRYHREIHIPDRTTDDGEVAFGMDIFASGENVADMVMSADEEHRLRARLVWALGRLSPDQRDLLRRVYGECQSLVSVSEELNCSRQAIQRRHERAIRKLRRYLSTDFKDVRVH
>NZ_CP019721.1|WP_004694443.1|568716_569781_-|ATP-binding-protein
MNFVGRAEIIERIQSRIAMGQMSLCVVYGPHRSGKSYVASQLVRRHKAIYLAGRMANESVHVADINRALEARFVPANAQDTFEPVESLQQAFVRLFESSVKTPQTVVIDDYPSLVEAVPQFPIHLRDLLDTYKDTSRLNIILMANGLEQLDGRIIGDRSLIGPFVSEYLEVKPFSLVDMKSLGLHYAKDDLRTVFAVTGGLPAYVQYFDNGESIDTNIINLFFSVTGALFEETQYILHRDMKNITGANAILTGLASLERPYYVELLQESQIKSGTFTSRLNDLMSMGLVGRIQASNRGNAKYADYHFTNSMFHFWYRYVYKYWGDIVRGYGADVYYNHVKPQLKDFVQAACIAI
>NZ_CP019721.1|WP_077707855.1|570256_571405_-|glycosyl-hydrolase-family-3
MNQFFRRVLSGLALLVAVVGTTGCQHESQAEQETVRTVSYRAVLESNKPVSEKVDTWIAAMSQEDKVGQLMMISLHGSTIGQSQKDVIRKYRVSGVMLTNENLINKNQVKTFTSDIMQTAITSSMVTPYIAVYRDRILHGNESFLRLPKPNRWGQLPMDRIINLATRSAIEMRDMGFNLVIGPNANLGVPNMSYTSDPTWAGHINLAMVERYQINHMWSAYNYFPAVTLGDASFGSANEAKAYLSNNDVAVFKRLIAQTTANSYMLVMSHIQIPAIDNEHLASSSKPIIDGWLRKELGYKGIVMTDRIDVGALQSNQKIGDYAVASILAGSDLILVDADTIHIDEVHRALTQAVADGTITTERLNESVKRILLMKMQTQMDP
>NZ_CP019721.1|WP_077707856.1|571818_573249_-|iron-hydrogenase-small-subunit
MSQYEFIDKRVPIALDNPSIYHDISKCKNCTLCRRACADVMSVLDYYDLDANGDVPVCIHCGQCAAACPFDSMHAKSELEKVKAALADPEKIVVIQTAPAVRVSIGEGFGYEPGTFLEGKMVGALRKLGADYVVDTNFGADLTIMEEASELVERLKNGGQIPQFTSCCPAWVRFAEIYFPELIPNLSSTRSCIAMEAAMIKTYFAEKKGIDPRNIVSVSVNPCTAKKAETKREEENAAARYHNDESLGMDTDISITTREFIRWIQEEHIDFNTVEESQFDDLIGMETGASIIFGNTGGVMEAALRTAYKLITDKEPPPYALTHLEDVRGMEGVKEATVQLGDDVTLSVAVVHGGKNTRDFLNALKDSGKHYDFIEVMACPGGCIGGGGQPRTKLPQAVKTKEARIGGLYEADENYKWVASYENEEIQTLYKDFLGEPLGHKAHELLHTHYTDRSAVLGTRKDVTPETCPTSPKFKG
>NZ_CP019721.1|WP_004694437.1|573572_573947_-|hypothetical-protein
MKKTLAAVLAAGALLIGGIGSVDAANWYTVGTDSNGVTWSIDNDSVKKDDKKAVMDIKAMDYEGYHYIVTEEFNHKKREVKDLKVTLYNPQGYVVKEEQVNKNSRKVEPGTPAYAVFQLIWGGK

Crispr_ID: NZ_CP019721_7

• CRISPR_ID: NZ_CP019721_7
• CRISPR_location: 562598-563513
• CRISPR_type: TypeI
• Repeat_type: NA
• Spacer_info: 12 spacers
• Cas_protein_info: csx1,cas2,cas1,csx20,cas10,csm3gr7,cas6,csa3

Consensus repeat of NZ_CP019721_7

Consensus_repeat	Method
GTTTCAATACCGTAAACGGTAAGNACTGTTGCAAC	CRT
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	CRISPRCasFinder
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	PILER-CR

spacers of NZ_CP019721_7

>7.1|562633|40|NZ_CP019721|CRT
CGCACTTAATGAAGCAAGAAGTTCCCTTGAACGAAATGCA
>7.2|562708|38|NZ_CP019721|CRT,CRISPRCasFinder
GAGGGTAAATAAAATATGTGTGTAATTGCATATGCTAG
>7.3|562781|35|NZ_CP019721|CRT,CRISPRCasFinder
GATAAAACAAGTGCATCTAGTGCTAACGTATGCCA
>7.4|562851|37|NZ_CP019721|CRT,CRISPRCasFinder,PILER-CR
GCCCAACAGAAGGGTATATCCATAACGATCTAATGGA
>7.5|562923|41|NZ_CP019721|CRT,CRISPRCasFinder,PILER-CR
AAAAAACTAATTGATGCGTGGAGCTGGCTCAACTCCGATAA
>7.6|562999|40|NZ_CP019721|CRT,CRISPRCasFinder,PILER-CR
TTGTAGACATTCTAATCATAGCTCCAAGCTTGATTGGACA
>7.7|563074|37|NZ_CP019721|CRT,CRISPRCasFinder,PILER-CR
CTGATTGGGAAGGCCGTCCCGATGGGGCGGTCGAAAT
>7.8|563146|36|NZ_CP019721|CRT,CRISPRCasFinder,PILER-CR
CTTCTTGAATAATTTTATCTATCTGATCAAATGTCA
>7.9|563217|38|NZ_CP019721|CRT,CRISPRCasFinder,PILER-CR
TTCAGCTCAATAAGACAAGGAATTGAAATAAAATTATA
>7.10|563290|43|NZ_CP019721|CRT,CRISPRCasFinder,PILER-CR
TTTCTAATATAGCACTTACTGATGAGTATGCATTTAGTGGTCA
>7.11|563368|36|NZ_CP019721|CRT,CRISPRCasFinder,PILER-CR
GGAAAAGAGAGTTGAAAAAATGGTCGAATATAGATG
>7.12|563439|40|NZ_CP019721|CRT,CRISPRCasFinder,PILER-CR
AAATTCCAACAGTATCGCTACTGCTGTTAAGACCGAGTTG

CRISPR arrays and Neighbor proteins around NZ_CP019721_7

CRISPR arrays

The CRISPR arrays of NZ_CP019721_7

>merge|NZ_CP019721|7|562598-563513|CRT,CRISPRCasFinder,PILER-CR
TATACACATATCGTAACGATAAATACTATTGCAACCGCACTTAATGAAGCAAGAAGTTCCCTTGAACGAAATGCAGTTTCAATACCGTAAATAGTAAGTACTATTGCAACGAGGGTAAATAAAATATGTGTGTAATTGCATATGCTAGATTTCAATACCATAAACGATAGGTACTGTTGCAACGATAAAACAAGTGCATCTAGTGCTAACGTATGCCAGTTTCAATACCGTAAACGGTAAGTACTGTTGCAACGCCCAACAGAAGGGTATATCCATAACGATCTAATGGAGTTTCAATACCGTAAACGGTAAGTACTATTGCAACAAAAAACTAATTGATGCGTGGAGCTGGCTCAACTCCGATAAGTTTCAATACCGTAAACGGTAAGCACTGTTGCAACTTGTAGACATTCTAATCATAGCTCCAAGCTTGATTGGACAGTTTCAATACCGTAAACGGTAAGCACTGTTGCAACCTGATTGGGAAGGCCGTCCCGATGGGGCGGTCGAAATGTTTCAATACCGTAAACGGTAAGCACTGTTGCAACCTTCTTGAATAATTTTATCTATCTGATCAAATGTCAGTTTCAATACCGTAAACGGTAAGCACTGTTGCAACTTCAGCTCAATAAGACAAGGAATTGAAATAAAATTATAGTTTCAATACCGTAAACGGTAAGCACTGTTGCAACTTTCTAATATAGCACTTACTGATGAGTATGCATTTAGTGGTCAGTTTCAATACCGTAAACGGTAAGCACTGTTGCAACGGAAAAGAGAGTTGAAAAAATGGTCGAATATAGATGGTTTCAATACCGTAAACGGTAAGCACTGTTGCAACAAATTCCAACAGTATCGCTACTGCTGTTAAGACCGAGTTGGTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC

>NZ_CP019721|7|6|562598-563513|CRT
TATACACATATCGTAACGATAAATACTATTGCAAC	CGCACTTAATGAAGCAAGAAGTTCCCTTGAACGAAATGCA
GTTTCAATACCGTAAATAGTAAGTACTATTGCAAC	GAGGGTAAATAAAATATGTGTGTAATTGCATATGCTAG
ATTTCAATACCATAAACGATAGGTACTGTTGCAAC	GATAAAACAAGTGCATCTAGTGCTAACGTATGCCA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GCCCAACAGAAGGGTATATCCATAACGATCTAATGGA
GTTTCAATACCGTAAACGGTAAGTACTATTGCAAC	AAAAAACTAATTGATGCGTGGAGCTGGCTCAACTCCGATAA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	TTGTAGACATTCTAATCATAGCTCCAAGCTTGATTGGACA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	CTGATTGGGAAGGCCGTCCCGATGGGGCGGTCGAAAT
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	CTTCTTGAATAATTTTATCTATCTGATCAAATGTCA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	TTCAGCTCAATAAGACAAGGAATTGAAATAAAATTATA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	TTTCTAATATAGCACTTACTGATGAGTATGCATTTAGTGGTCA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	GGAAAAGAGAGTTGAAAAAATGGTCGAATATAGATG
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	AAATTCCAACAGTATCGCTACTGCTGTTAAGACCGAGTTG
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC

>NZ_CP019721|7|6|562673-563513|CRISPRCasFinder
GTTTCAATACCGTAAATAGTAAGTACTATTGCAAC	GAGGGTAAATAAAATATGTGTGTAATTGCATATGCTAG
ATTTCAATACCATAAACGATAGGTACTGTTGCAAC	GATAAAACAAGTGCATCTAGTGCTAACGTATGCCA
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GCCCAACAGAAGGGTATATCCATAACGATCTAATGGA
GTTTCAATACCGTAAACGGTAAGTACTATTGCAAC	AAAAAACTAATTGATGCGTGGAGCTGGCTCAACTCCGATAA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	TTGTAGACATTCTAATCATAGCTCCAAGCTTGATTGGACA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	CTGATTGGGAAGGCCGTCCCGATGGGGCGGTCGAAAT
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	CTTCTTGAATAATTTTATCTATCTGATCAAATGTCA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	TTCAGCTCAATAAGACAAGGAATTGAAATAAAATTATA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	TTTCTAATATAGCACTTACTGATGAGTATGCATTTAGTGGTCA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	GGAAAAGAGAGTTGAAAAAATGGTCGAATATAGATG
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	AAATTCCAACAGTATCGCTACTGCTGTTAAGACCGAGTTG
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC

>NZ_CP019721|7|6|562816-563513|PILER-CR
GTTTCAATACCGTAAACGGTAAGTACTGTTGCAAC	GCCCAACAGAAGGGTATATCCATAACGATCTAATGGA
GTTTCAATACCGTAAACGGTAAGTACTATTGCAAC	AAAAAACTAATTGATGCGTGGAGCTGGCTCAACTCCGATAA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	TTGTAGACATTCTAATCATAGCTCCAAGCTTGATTGGACA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	CTGATTGGGAAGGCCGTCCCGATGGGGCGGTCGAAAT
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	CTTCTTGAATAATTTTATCTATCTGATCAAATGTCA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	TTCAGCTCAATAAGACAAGGAATTGAAATAAAATTATA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	TTTCTAATATAGCACTTACTGATGAGTATGCATTTAGTGGTCA
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	GGAAAAGAGAGTTGAAAAAATGGTCGAATATAGATG
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC	AAATTCCAACAGTATCGCTACTGCTGTTAAGACCGAGTTG
GTTTCAATACCGTAAACGGTAAGCACTGTTGCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019721.1|WP_077707855.1|570256_571405_-|glycosyl-hydrolase-family-3	unknown	unknown	gnl|CDD|366376
NZ_CP019721.1|WP_077707850.1|555023_557042_+|hypothetical-protein	csx1	cd09732_csx1_CAS-III	unknown
NZ_CP019721.1|WP_004694437.1|573572_573947_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077708641.1|557102_559247_-|TM1812-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	gnl|CDD|378186
NZ_CP019721.1|WP_077707849.1|549148_549568_-|DUF805-domain-containing-protein	unknown	unknown	gnl|CDD|377540
NZ_CP019721.1|WP_077707853.1|566631_567240_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707854.1|567559_568426_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NZ_CP019721.1|WP_077707852.1|563955_564726_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	gnl|CDD|273848
NZ_CP019721.1|WP_077707848.1|547745_548744_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|376633
NZ_CP019721.1|WP_077707846.1|544905_545553_-|CRISPR-associated-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|377130
NZ_CP019721.1|WP_077707851.1|559388_561785_+|hypothetical-protein	unknown	unknown	gnl|CDD|379100
NZ_CP019721.1|WP_077707856.1|571818_573249_-|iron-hydrogenase-small-subunit	unknown	unknown	gnl|CDD|274171
NZ_CP019721.1|WP_077707858.1|575259_576615_+|MFS-transporter	unknown	unknown	gnl|CDD|129794
NZ_CP019721.1|WP_004698032.1|576929_577301_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_008601954.1|548758_549037_-|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|378256
NZ_CP019721.1|WP_008601959.1|547187_547553_-|hypothetical-protein	csx20	cls000118_csx20_CAS-I:CAS-III	unknown
NZ_CP019721.1|WP_187658829.1|552642_552843_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707857.1|574059_575157_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042
NZ_CP019721.1|WP_004694443.1|568716_569781_-|ATP-binding-protein	unknown	unknown	gnl|CDD|379062
NZ_CP019721.1|WP_077707847.1|545555_547157_-|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	gnl|CDD|274209

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP019721.1|WP_077707850.1|555023_557042_+|hypothetical-protein	csx1	cd09732_csx1_CAS-III	3.4e-11	37.9	0.1
NZ_CP019721.1|WP_008601954.1|548758_549037_-|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	1e-18	62.2	0.4
NZ_CP019721.1|WP_077707852.1|563955_564726_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	7.3e-17	56.8	0.1
NZ_CP019721.1|WP_077708641.1|557102_559247_-|TM1812-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	4.2e-12	40.9	4.9
NZ_CP019721.1|WP_008601959.1|547187_547553_-|hypothetical-protein	csx20	cls000118_csx20_CAS-I:CAS-III	1.1e-58	192.0	0.0
NZ_CP019721.1|WP_077707847.1|545555_547157_-|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	9.6e-79	260.0	0.0
NZ_CP019721.1|WP_077707857.1|574059_575157_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	3.3e-11	38.4	0.0
NZ_CP019721.1|WP_077707846.1|544905_545553_-|CRISPR-associated-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	9.6e-38	124.4	0.0
NZ_CP019721.1|WP_077707848.1|547745_548744_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	7.2e-75	246.6	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP019721.1|WP_077707855.1|570256_571405_-|glycosyl-hydrolase-family-3	gnl|CDD|366376	pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain.	4.47107e-31
NZ_CP019721.1|WP_077708641.1|557102_559247_-|TM1812-family-CRISPR-associated-protein	gnl|CDD|378186	pfam09455, Cas_DxTHG, CRISPR-associated (Cas) DxTHG family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. The family describes Cas proteins of about 400 residues that include the motif [VIL]-D-x-[ST]-H-[GS]. The CRISPR and associated proteins are thought to be involved in the evolution of host resistance. The exact molecular function of this family is currently unknown.	0.00192657
NZ_CP019721.1|WP_077707849.1|549148_549568_-|DUF805-domain-containing-protein	gnl|CDD|377540	pfam05656, DUF805, Protein of unknown function (DUF805). This family consists of several bacterial proteins of unknown function.	6.22624e-10
NZ_CP019721.1|WP_077707854.1|567559_568426_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	3.18865e-14
NZ_CP019721.1|WP_077707852.1|563955_564726_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl|CDD|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	0.000585577
NZ_CP019721.1|WP_077707848.1|547745_548744_-|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	4.40622e-95
NZ_CP019721.1|WP_077707846.1|544905_545553_-|CRISPR-associated-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.49345e-12
NZ_CP019721.1|WP_077707851.1|559388_561785_+|hypothetical-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	0.00177802
NZ_CP019721.1|WP_077707856.1|571818_573249_-|iron-hydrogenase-small-subunit	gnl|CDD|274171	TIGR02512, Periplasmic_hydrogenase_large_subunit, [FeFe] hydrogenase, group A. This model describes iron-only hydrogenases of anaerobic and microaerophilic bacteria and protozoa. This model is narrower, and covers a longer stretch of sequence, than pfam02906. This family represents a division among families that belong to pfam02906, which also includes proteins such as nuclear prelamin A recognition factor in animals. Note that this family shows some heterogeneity in terms of periplasmic, cytosolic, or hydrogenosome location, NAD or NADP dependence, and overal protein protein length.	0
NZ_CP019721.1|WP_077707858.1|575259_576615_+|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.72685e-42
NZ_CP019721.1|WP_008601954.1|548758_549037_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	3.83589e-14
NZ_CP019721.1|WP_077707857.1|574059_575157_-|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	9.16581e-13
NZ_CP019721.1|WP_004694443.1|568716_569781_-|ATP-binding-protein	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	3.42348e-06
NZ_CP019721.1|WP_077707847.1|545555_547157_-|hypothetical-protein	gnl|CDD|274209	TIGR02578, CRISPR-associated_protein_Cas10/Csm1, CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2. A typical example is TM1811 from Thermotoga maritima. CRISPR are Clustered Regularly Interspaced Short Palindromic Repeats. This protein family belongs to a conserved gene cluster regularly found near CRISPR repeats.	3.09865e-05

Protein sequences

>NZ_CP019721.1|WP_077707851.1|559388_561785_+|hypothetical-protein
MYIFKRESIMATTTNYLNDLASMRQFIRSLTFGNHNRGKATVRGIKESQHDDVIRRLDYFDIIRHIYTQRIGKTSIHHLAKDDFVDGYNYLNNLYELYAAVPEQIYVQLCILSYIGANDDVTITDLYTNLNQEPYLDHYIDLVENLYEQRNKKQEPPCIIDQQYIQRQVKTLEILGAITKTELTKGYTYSIKPTIIEELSKQQLQELAMAVFFYTNVSITSAAGHILLKKIMYLINDFSLKDQQKCMYYDFNNTYFSFKDNNPNNVIDGDIFYPLADALHRQKKVRLSFYESGKPREIVSPLALQTYYGENKNMLCSINNGRIQWNRIDRIKSLEVTKYNSTNTVPQIQTKDKTFDTCIIHFLTLKDYDLVYDKFIRHFKESLTVLSSTDEYIELQLEVQDALQLLPQLRSYLPYVYITYTNKSSIKDKFYNNLYASLNIDFVEPEGYKKRKKINRFLHPLQRKESDNNKTKKDKDLDGTYVSSVLNDINAITFTTQYQLQLDLINGVVHTKQDIEGLINHRRLLTPAPYKKVLRNDDYEQFLADALVEPNENGEEVESILPDLPLVIISDAERMFLKDLISDTRANWLLSPELCQILSTELETVDTTFPRGSWTRVPTMTDDTPLTMQVITQCLQAIQNNERIMIQDKELSPCRIEYSVGSNGYTLIAYDHATDTFLDYPLRNESNIIKTAAPRLEDIETIYANYRDESKRTVTFTLYDANNAVDRCFNYFSNYTIQAKDINDEEFTIEVSYLPFQEIDILRHLLKLGCAVRITDDSPLKKQLETIYKTALIHAPSI
>NZ_CP019721.1|WP_077708641.1|557102_559247_-|TM1812-family-CRISPR-associated-protein
MAIHNIFLSFLSKVSNTSIKTIVNTDIEDAIRSSIATNESSLKYILYHTWKDEKTRDISFDKIYLLCTDGVMAHQSNSPSSYDIFVNQMCKFYNVMGHNEQAFFDALDHVPCGTDLDDISRIKSSIIEMSKKILDFKDTFTNDKDEVRLYMDITGGPRNAAMILLVISRLLAYHGIIVDDVYYSGYKEIENGPGEITVHKVLDIYELFDIIAGFEEFKLFGSAKKLNTYFKSPENIGTGNIESTATATKKLLKAMDSFSEAINISSRGAFEKSIARLDDSLSLVHSMANNTDNNKTFDQELIELLHKPIEQSYTTLLQHHRNHASDELAYIDWCLDHDYLQQALTLFCEYVPEYAVDKGIIKCDSLVFNAYYEDTQQNKEKRLLQAAIKAWNRAGNNIHFSTFYNVVMPDHDKKTSEKDARSMPMRLFNSINNARMQYLAAMINAKKDEVAPNIDKVITYYIKFVRNEKKKIQIVERDLQKQKERIHLMVDEETTKLREKCEVLLNQYGFTLYLQDDRYAENYTLLEYILFLQDILESVENIEAFNNILESLRKNIISEVLSKEEFKEYIICDADNSSFRLKKTSMLARNVVCNAILNHLIEEKKYKAYKSLIMHQLPDTKDSAVTAAELLLSQKKSNHRGVPLFEVSGVYIPHVLLDDIAKTMKFIEQYFEIKKARNDSNHANKEVLCKYTTSQELLDEMRKCVAMARELSRK
>NZ_CP019721.1|WP_077707850.1|555023_557042_+|hypothetical-protein
MEHHIYLTFLSTLHTKNNPYNPQKLEKTVVNLTEIAPFNVIRQTNESALKYLLHNKRKENSTFKLDKLFFFKSPEMENTFKESTISSLNVFEEQMCDYINKTSIPITWSPETINYIDCGDIDYIDNLKDSIIDMSQAIMEYYKSKSSDDRVILHVDLSGGPRTAIMLMIAIIRLVAFQGIEIGSILYANVNANNNSIVRVYEGNSIYNIYDMITGFAEFNQFGSVDTLKNYVNTLDNPDVQIKELISSMGDFSEAVRLSSRGIFQRSMEDIHKLLTDIESSKQEIPANNRENHKNFEIEALKLMSGKIQNNYKTVLANKEDDLAYIDWCLDNGYLQQALALFAEFVPRAILESKMIILDDTIFPTDSDNELSASMENFNTINEYTAKTMEIVNNRATKINNKIKSVLLKYFSGDFSKESKRIIKEVLKDKKNNTSTNITREDTQYPKFEEQLINDINQIILKEAEKEPHNYLKYKTFTNNNVNVPSKLLRLISNIGINTKSIVGINEFSKDIRRYFTAALVHQLKEIKDLPSDVVTVNDQYEITLNDTNKLFKVRDAFISIFTNSNNDDIYRFLFANFVSYQYPIDLFPHQLYGIDGLTLNSVLKSNPEKITQVARILNLYRTLKGSRNDTAHAREEKRGQFIESEDIKRELKQCLNDIRKVREYICTYNQQ
>NZ_CP019721.1|WP_187658829.1|552642_552843_-|hypothetical-protein
MQQYLLFTVLKQPDGPGFFESIILLQQYLPFTVCAEGCETAEEQSDDEVRTSQVPERSEGKTKVTK
>NZ_CP019721.1|WP_077707849.1|549148_549568_-|DUF805-domain-containing-protein
MIIKEGIMENLQQELKSMLSLSGRMNRRSYFMNLLMIIGIGYLGGLCISLAPVSKFFWVLGWSIIGYSVVRELAIASRRIHDLNGPTYLAGIYIVAAIIAIFEPTLAKIMGFVKIGLVLMPGDEDPNNYGERPDSMIVV
>NZ_CP019721.1|WP_008601954.1|548758_549037_-|CRISPR-associated-endonuclease-Cas2
MMRYLISYDISDTKIRNKVVKYLESFCYRVQYSVFLCVHAHVRVETIAKKLEVLTQGDETRRLLIVSISDTAKTPIWCNKMIPLTEDKMLII
>NZ_CP019721.1|WP_077707848.1|547745_548744_-|CRISPR-associated-endonuclease-Cas1
MMLETLYVMTPGISIRQDGGLLVLEKDHSVIKEIPIATVSNLVLGRTIQISTQVMFSLVKQGSLIQFVDHKYQLVGTLGDEHTTLQRLLWQVACFQNQEFALDGAKYIVRRKIKGQIALLNQYKKSKCIPNFVVVHRTMQALLKRVERTKKVDTLRGIEGLASRTYFSVLGHVLSEPWEFSGRKRHPSPDPVNAILSYGYSFLEREVRACLLTAGLDVRIGVLHSTNNRKDSLVYDVMDIFRQDIIDRFVLKLLNRHMMLPEDFDLSERGCFLSKETNKKWVELYEDYMKAELSRLDNLAPRKWIQQEIQAFISYLKSLGETVDIEKSENIS
>NZ_CP019721.1|WP_008601959.1|547187_547553_-|hypothetical-protein
MFINHTNHPSQYWSDEQLAAAHQYGEVVDIPFPLIDPALPSGEIGQLVQEYAGRIISLNPQAVLCQGEFVYCHALVERLLAVGITVLVATSERLVSESYEAGINEKIVNFQFVQFREYCHL
>NZ_CP019721.1|WP_077707847.1|545555_547157_-|hypothetical-protein
MQVNAILFDVQSIQKYIFANNKLKANVGASFIVDRLFEDVLCKEIINKLGVEADTTSWLTRSDSITSLPKTIYVAYIGGGNALVLIDDKHESLVQDIVKKFTTQVLVQYPGLKVGATTGYITLDGTQFSADLGKLYKQLKANQFALNPIVHPANTGLTTICDFSGDVADTTQSFGDEKRLVATSFTAKFEAFEAANSRLKIDLFGTETTDWVFPSEFEELGQNQSTEKSKTGINDIAIVHIDGNNMGAHFRQCKTLEERSALSKRVATKTLESFKALVQWIIDKYDILDENLELSKNMLPIRPIIIGGDDITFICNARIAVQASHYLMQQLLSDKNGISISSCAGIAVIPTSYPFFRGYEMAEQLCDSAKSKMREYNAVHKVNESCWMDFAFLHGETAPTLEQFFANEYSSLTGNMHFGPYQVFNDNIEAEKDIFALSKLLECTNQFILVKDKAYSGDLLAHNKVKELRSVLQDNEHMWTVFLEQLRNTNKFMPTVSGWDAFKEKLWAKVNGKMRTPYVDAIELMDYVLPGLE
>NZ_CP019721.1|WP_077707846.1|544905_545553_-|CRISPR-associated-protein
MYTLTIKLLSPTMLMSGQGDVNTDSTIVHDRYGIPFIPAKRVRGVLYESAIEVAEMMHAAGLNTFTIDDVKVLFNRLEGAEDNPRLSISNLTIADYDVVASELAALEEQYPAVFTKERVLEEYTSMRYYTSIDQVTGTALEGTLHNSRVLNRALAFSGQIDVEDMTEIERLILACAVRNLTGIGGKRNRGFGQVECTIDDASFDLESLGGTLWNK
>NZ_CP019721.1|WP_077707852.1|563955_564726_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MSDNVEIMSIELVIVADLSIKIVQSIGSVLHGVLMELVGTEYAGQLHETGLRPYSQYIYFDKHKKQYIWRLSAVTADAVNRIVRPTLEMPEKIFLKQKRGYLYIKDRTILEETSYEALIHKFWSSDAFYSQTKLQCMSTTSFKVDQQYTIFPEAFRIYRYLLRQWNHFSTFGTMDADSLIDTFEKGVFIRDYNLRMGIYSLEGIKIRGFRGQIVMQFKRNIELQKILALLSYYSQFTGLGIKTALGMGGVKCEIIE
>NZ_CP019721.1|WP_077707853.1|566631_567240_-|hypothetical-protein
MAIDDKPTDLMAARLSKGEDLDLIYTNPKNHIVCFIPTYQPSGGDSTKCYFVDGREEMVHLPMRTITRELAMQEGLRPNYIMTSDGRRSSYTAPKTYGPHLTFAHIKCRRPIGKDVVYGLFNVAIPYEYIVTEGPEPDTSYIHVADFAPILVYQSPRHVKHKLNEAMLEHCNYVRKMLARIKLSQNPQVVAELFIAWRDLTR
>NZ_CP019721.1|WP_077707854.1|567559_568426_-|sigma-70-family-RNA-polymerase-sigma-factor
MLYTNEEPLVQKICIKTANLQHDNYQSETLETQALPSHSLLSKADESTRSIPEELKLQTLVCGHQVLSSLSDKSLVSICQKPNMRIQTVGYQPWSVDELRHDAAQIELCRRYRPLILHYTNRMGNREFREDVESYLWAILIESIYSFDLNGTVPFPGFVKAGIMYGYMRYWKRERLRYHREIHIPDRTTDDGEVAFGMDIFASGENVADMVMSADEEHRLRARLVWALGRLSPDQRDLLRRVYGECQSLVSVSEELNCSRQAIQRRHERAIRKLRRYLSTDFKDVRVH
>NZ_CP019721.1|WP_004694443.1|568716_569781_-|ATP-binding-protein
MNFVGRAEIIERIQSRIAMGQMSLCVVYGPHRSGKSYVASQLVRRHKAIYLAGRMANESVHVADINRALEARFVPANAQDTFEPVESLQQAFVRLFESSVKTPQTVVIDDYPSLVEAVPQFPIHLRDLLDTYKDTSRLNIILMANGLEQLDGRIIGDRSLIGPFVSEYLEVKPFSLVDMKSLGLHYAKDDLRTVFAVTGGLPAYVQYFDNGESIDTNIINLFFSVTGALFEETQYILHRDMKNITGANAILTGLASLERPYYVELLQESQIKSGTFTSRLNDLMSMGLVGRIQASNRGNAKYADYHFTNSMFHFWYRYVYKYWGDIVRGYGADVYYNHVKPQLKDFVQAACIAI
>NZ_CP019721.1|WP_077707855.1|570256_571405_-|glycosyl-hydrolase-family-3
MNQFFRRVLSGLALLVAVVGTTGCQHESQAEQETVRTVSYRAVLESNKPVSEKVDTWIAAMSQEDKVGQLMMISLHGSTIGQSQKDVIRKYRVSGVMLTNENLINKNQVKTFTSDIMQTAITSSMVTPYIAVYRDRILHGNESFLRLPKPNRWGQLPMDRIINLATRSAIEMRDMGFNLVIGPNANLGVPNMSYTSDPTWAGHINLAMVERYQINHMWSAYNYFPAVTLGDASFGSANEAKAYLSNNDVAVFKRLIAQTTANSYMLVMSHIQIPAIDNEHLASSSKPIIDGWLRKELGYKGIVMTDRIDVGALQSNQKIGDYAVASILAGSDLILVDADTIHIDEVHRALTQAVADGTITTERLNESVKRILLMKMQTQMDP
>NZ_CP019721.1|WP_077707856.1|571818_573249_-|iron-hydrogenase-small-subunit
MSQYEFIDKRVPIALDNPSIYHDISKCKNCTLCRRACADVMSVLDYYDLDANGDVPVCIHCGQCAAACPFDSMHAKSELEKVKAALADPEKIVVIQTAPAVRVSIGEGFGYEPGTFLEGKMVGALRKLGADYVVDTNFGADLTIMEEASELVERLKNGGQIPQFTSCCPAWVRFAEIYFPELIPNLSSTRSCIAMEAAMIKTYFAEKKGIDPRNIVSVSVNPCTAKKAETKREEENAAARYHNDESLGMDTDISITTREFIRWIQEEHIDFNTVEESQFDDLIGMETGASIIFGNTGGVMEAALRTAYKLITDKEPPPYALTHLEDVRGMEGVKEATVQLGDDVTLSVAVVHGGKNTRDFLNALKDSGKHYDFIEVMACPGGCIGGGGQPRTKLPQAVKTKEARIGGLYEADENYKWVASYENEEIQTLYKDFLGEPLGHKAHELLHTHYTDRSAVLGTRKDVTPETCPTSPKFKG
>NZ_CP019721.1|WP_004694437.1|573572_573947_-|hypothetical-protein
MKKTLAAVLAAGALLIGGIGSVDAANWYTVGTDSNGVTWSIDNDSVKKDDKKAVMDIKAMDYEGYHYIVTEEFNHKKREVKDLKVTLYNPQGYVVKEEQVNKNSRKVEPGTPAYAVFQLIWGGK
>NZ_CP019721.1|WP_077707857.1|574059_575157_-|winged-helix-turn-helix-transcriptional-regulator
MSITIRFSDYALETNETLIQRIQFVYSPLNELFRSLHVLLNPRHHGTNIDWVIEIQDKLTEEFYENLHYFQLFYELGVSPILLCNFRYHMTTIEEEIQNLKKFLVNYPTIQLIEYLERIIDDRENAFIPTLAKGLEWKDFSLNENDQLLKDLKRNATSVYRRFFSFIDWYRKSIFDDTWKEKSIEQKLLIEIQKQSSFLREKGFIEMFNHLQIDRIHWEKGALAIIKPFNQEVYLKDSDSIMLLPSYFIWPHLFVESFNQGIAITYDIAEQPSYYNSTPEGLVTIFKALSDSVRLQIMNYVLEKPSTTQSLAQILLMTESSVSRHLQILKDAKLLKARKVKKFVLYEPTELVTQLMPNFYRFFRN
>NZ_CP019721.1|WP_077707858.1|575259_576615_+|MFS-transporter
MNKQLQDLLITIVAGMGMLLSTLDTGIINIALPFLKEQFQTSTDIAAFTITGYTLALAISILPLGVLSDKFGKLKISYLGFVLFGLSSLFCGLINNISLLIIGRIFQGIGAAALQATSAALITTLVSEKRKNSSIGILGIMIGLGPILGPSLGGIILSLSFWQLIFLINIPFVILGIACNNFLLNKLSEKNNNRQLDMLGITINTLMLVSLLLGLSLLNKSHLFVVGIILILSSLLLGIIFYYMELKNKHALIDIKGLKNNPQVISYLFQTVTFGFASAMIFLLPPFIFEQSYHLEVGQTGFLVLGAPTGLVLFSRISSKINNGNKNKLFSHIGLSIIIISLIFLLLINPNWPYQLLTLGLFIYGIGGGYFQPANIASIMQASPMEIQGSTGALQRMLQNVAISIGSAIGATCLNIWSNDLLLATRIGWGITLILVIISLKEVFKFSHHNS
>NZ_CP019721.1|WP_004698032.1|576929_577301_-|hypothetical-protein
MKKWLAAMFAAGVFFVGGFGQASAADWYYIDADADDAAWFIDNSSVYKTDDAATVLVKINNVEGFTYIYTVRIDRKEKTWTELDTTVYSNAGIALLSSKQAQKPTKIEPDTMGAEVMQALWGK

Crispr_ID: NZ_CP019721_8

• CRISPR_ID: NZ_CP019721_8
• CRISPR_location: 564911-566267
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 17 spacers
• Cas_protein_info: cas6,csx1,cas2,cas1,csx20,cas10,csa3

Consensus repeat of NZ_CP019721_8

Consensus_repeat	Method
GTTTCCGTCCCCNNANGGGGATNATTTAATTTAAC	CRT
GTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC	CRISPRCasFinder
GGGGATCATTTAATTTAAC	PILER-CR

spacers of NZ_CP019721_8

>8.1|564946|44|NZ_CP019721|CRT
ATTAGACATGAATTGCTGCATATCATTAATGATGATTTCCATAT
>8.2|565025|47|NZ_CP019721|CRT
TCTCAATATGTGTTCAATGACGGCAAAACTAGCGGCCAAGAAAAAGG
>8.3|565107|43|NZ_CP019721|CRT
AATCACGTAGTATGAACGCTAATGATTATTGCTGGGTTTTATG
>8.4|565185|39|NZ_CP019721|CRT,CRISPRCasFinder
GAAAAAGTAGAGGGTAAAGAATACAAAAAAATGGTATTC
>8.5|565259|42|NZ_CP019721|CRT,CRISPRCasFinder
CATTAGCTGTAATTTCAATGATGACAACAGGAGTTGTCTTTG
>8.6|565336|38|NZ_CP019721|CRT,CRISPRCasFinder
TTAAGGAGGACGAGGAATAATGGGCTATATGTTAATTG
>8.7|565409|43|NZ_CP019721|CRT,CRISPRCasFinder
TAGCACGATTCAAGATGTTTAATGTCATGTTGAATGGTAACGT
>8.8|565487|43|NZ_CP019721|CRT,CRISPRCasFinder
AATTCATCAATATGATGCGTTCATTTACAACGATGAACACAGT
>8.9|565565|44|NZ_CP019721|CRT,CRISPRCasFinder
ACAAGTCCAGGTGATTTAAAGATCGGAGACGCTACTCCGTTAAT
>8.10|565644|43|NZ_CP019721|CRT,CRISPRCasFinder
GTTAGACCGACTAAATCGCTGATGCGGAGACCAGAGTTAATTC
>8.11|565722|43|NZ_CP019721|CRT,CRISPRCasFinder
ATACATCAAATTTCTTTTATTGGTGTCAAGTTCGCCATAAAAA
>8.12|565800|42|NZ_CP019721|CRT,CRISPRCasFinder
TGTTTCTTCAATTTGTTTATTCATATTAACTACCTTTCTATT
>8.13|565877|44|NZ_CP019721|CRT,CRISPRCasFinder
TATATGGAATATACATATAGAACAATTCAAGATTATTTCTACAA
>8.14|565956|43|NZ_CP019721|CRT,CRISPRCasFinder
ACGTTTACATAGATTTCTTTATCTGAATAGATTCTAGAAACTA
>8.15|566034|41|NZ_CP019721|CRT,CRISPRCasFinder
GTACTTCTAACAATAGCTTCTTGATATTCATTATCTACCAT
>8.16|566110|44|NZ_CP019721|CRT,CRISPRCasFinder
TTCAAATATTGTATTCCATAATATCAAATCAGAAATAGATGTAA
>8.17|566189|44|NZ_CP019721|CRT,CRISPRCasFinder
GATAAAACGTGCGTATAAATCATTAGTTTTATTAAAGGAAGAAA
>8.18|565185|55|NZ_CP019721|PILER-CR
GAAAAAGTAGAGGGTAAAGAATACAAAAAAATGGTATTCGTTTCCGTCCCCCAAT
>8.19|565259|58|NZ_CP019721|PILER-CR
CATTAGCTGTAATTTCAATGATGACAACAGGAGTTGTCTTTGGTTTCCGTCCCCATCA
>8.20|565336|54|NZ_CP019721|PILER-CR
TTAAGGAGGACGAGGAATAATGGGCTATATGTTAATTGGTTTCCGTCCCCCAAT
>8.21|565409|59|NZ_CP019721|PILER-CR
TAGCACGATTCAAGATGTTTAATGTCATGTTGAATGGTAACGTATTTCCGTCCCCATCA
>8.22|565487|59|NZ_CP019721|PILER-CR
AATTCATCAATATGATGCGTTCATTTACAACGATGAACACAGTGTTTCCGTCCCCATTA
>8.23|565565|60|NZ_CP019721|PILER-CR
ACAAGTCCAGGTGATTTAAAGATCGGAGACGCTACTCCGTTAATGTTTCCGTCCCCTAAT
>8.24|565644|59|NZ_CP019721|PILER-CR
GTTAGACCGACTAAATCGCTGATGCGGAGACCAGAGTTAATTCGTTTCCGTCCCCTAAT
>8.25|565722|59|NZ_CP019721|PILER-CR
ATACATCAAATTTCTTTTATTGGTGTCAAGTTCGCCATAAAAAGTTTCCGTCCCCTAAT
>8.26|565800|58|NZ_CP019721|PILER-CR
TGTTTCTTCAATTTGTTTATTCATATTAACTACCTTTCTATTGTTTCCGTCCCCTAAT
>8.27|565877|60|NZ_CP019721|PILER-CR
TATATGGAATATACATATAGAACAATTCAAGATTATTTCTACAAGTTTCCGTCCCCTAAT
>8.28|565956|59|NZ_CP019721|PILER-CR
ACGTTTACATAGATTTCTTTATCTGAATAGATTCTAGAAACTAGTTTCCGTCCCCTAAT
>8.29|566034|57|NZ_CP019721|PILER-CR
GTACTTCTAACAATAGCTTCTTGATATTCATTATCTACCATGTTTCCGTCCCCTAAT
>8.30|566110|60|NZ_CP019721|PILER-CR
TTCAAATATTGTATTCCATAATATCAAATCAGAAATAGATGTAAGTTTCCGTCCCCTAAT
>8.31|566189|60|NZ_CP019721|PILER-CR
GATAAAACGTGCGTATAAATCATTAGTTTTATTAAAGGAAGAAAGTTTCCGTCCCCTAAT

CRISPR arrays and Neighbor proteins around NZ_CP019721_8

CRISPR arrays

The CRISPR arrays of NZ_CP019721_8

>merge|NZ_CP019721|8|564911-566267|CRT,CRISPRCasFinder,PILER-CR
AGAACCGGTCCCGTAAAAGGATTATTTAATTTAACATTAGACATGAATTGCTGCATATCATTAATGATGATTTCCATATGTTTCCGCCCCCTAAAGGGGATCATTTAATTTAACTCTCAATATGTGTTCAATGACGGCAAAACTAGCGGCCAAGAAAAAGGGGTTCCGTCCTCATCAGAGGTTTATTTAATTTAATAATCACGTAGTATGAACGCTAATGATTATTGCTGGGTTTTATGGTTTCCGTCCCCATCAGGGGATTATTTAATTTAACGAAAAAGTAGAGGGTAAAGAATACAAAAAAATGGTATTCGTTTCCGTCCCCCAATGGGGATTATTTAATTTAACCATTAGCTGTAATTTCAATGATGACAACAGGAGTTGTCTTTGGTTTCCGTCCCCATCAGGGGATTATTTAATTTAACTTAAGGAGGACGAGGAATAATGGGCTATATGTTAATTGGTTTCCGTCCCCCAATGAGGATTATTTAATTTAACTAGCACGATTCAAGATGTTTAATGTCATGTTGAATGGTAACGTATTTCCGTCCCCATCAGGGGATTATTTAATTTAACAATTCATCAATATGATGCGTTCATTTACAACGATGAACACAGTGTTTCCGTCCCCATTAGGGGATCATTTAATTTAACACAAGTCCAGGTGATTTAAAGATCGGAGACGCTACTCCGTTAATGTTTCCGTCCCCTAATGGGGATCATTTAATTTAACGTTAGACCGACTAAATCGCTGATGCGGAGACCAGAGTTAATTCGTTTCCGTCCCCTAATGGGGATCATTTAATTTAACATACATCAAATTTCTTTTATTGGTGTCAAGTTCGCCATAAAAAGTTTCCGTCCCCTAATGGGGATCATTTAATTTAACTGTTTCTTCAATTTGTTTATTCATATTAACTACCTTTCTATTGTTTCCGTCCCCTAATGGGGATCATTTAATTTAACTATATGGAATATACATATAGAACAATTCAAGATTATTTCTACAAGTTTCCGTCCCCTAATGGGGATCATTTAATTTAACACGTTTACATAGATTTCTTTATCTGAATAGATTCTAGAAACTAGTTTCCGTCCCCTAATGGGGATCATTTAATTTAACGTACTTCTAACAATAGCTTCTTGATATTCATTATCTACCATGTTTCCGTCCCCTAATGGGGATCATTTAATTTAACTTCAAATATTGTATTCCATAATATCAAATCAGAAATAGATGTAAGTTTCCGTCCCCTAATGGGGATCATTTAATTTAACGATAAAACGTGCGTATAAATCATTAGTTTTATTAAAGGAAGAAAGTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC

>NZ_CP019721|8|7|564911-566267|CRT
AGAACCGGTCCCGTAAAAGGATTATTTAATTTAAC	ATTAGACATGAATTGCTGCATATCATTAATGATGATTTCCATAT
GTTTCCGCCCCCTAAAGGGGATCATTTAATTTAAC	TCTCAATATGTGTTCAATGACGGCAAAACTAGCGGCCAAGAAAAAGG
GGTTCCGTCCTCATCAGAGGTTTATTTAATTTAAT	AATCACGTAGTATGAACGCTAATGATTATTGCTGGGTTTTATG
GTTTCCGTCCCCATCAGGGGATTATTTAATTTAAC	GAAAAAGTAGAGGGTAAAGAATACAAAAAAATGGTATTC
GTTTCCGTCCCCCAATGGGGATTATTTAATTTAAC	CATTAGCTGTAATTTCAATGATGACAACAGGAGTTGTCTTTG
GTTTCCGTCCCCATCAGGGGATTATTTAATTTAAC	TTAAGGAGGACGAGGAATAATGGGCTATATGTTAATTG
GTTTCCGTCCCCCAATGAGGATTATTTAATTTAAC	TAGCACGATTCAAGATGTTTAATGTCATGTTGAATGGTAACGT
ATTTCCGTCCCCATCAGGGGATTATTTAATTTAAC	AATTCATCAATATGATGCGTTCATTTACAACGATGAACACAGT
GTTTCCGTCCCCATTAGGGGATCATTTAATTTAAC	ACAAGTCCAGGTGATTTAAAGATCGGAGACGCTACTCCGTTAAT
GTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC	GTTAGACCGACTAAATCGCTGATGCGGAGACCAGAGTTAATTC
GTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC	ATACATCAAATTTCTTTTATTGGTGTCAAGTTCGCCATAAAAA
GTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC	TGTTTCTTCAATTTGTTTATTCATATTAACTACCTTTCTATT
GTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC	TATATGGAATATACATATAGAACAATTCAAGATTATTTCTACAA
GTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC	ACGTTTACATAGATTTCTTTATCTGAATAGATTCTAGAAACTA
GTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC	GTACTTCTAACAATAGCTTCTTGATATTCATTATCTACCAT
GTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC	TTCAAATATTGTATTCCATAATATCAAATCAGAAATAGATGTAA
GTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC	GATAAAACGTGCGTATAAATCATTAGTTTTATTAAAGGAAGAAA
GTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC

>NZ_CP019721|8|7|565150-566267|CRISPRCasFinder
GTTTCCGTCCCCATCAGGGGATTATTTAATTTAAC	GAAAAAGTAGAGGGTAAAGAATACAAAAAAATGGTATTC
GTTTCCGTCCCCCAATGGGGATTATTTAATTTAAC	CATTAGCTGTAATTTCAATGATGACAACAGGAGTTGTCTTTG
GTTTCCGTCCCCATCAGGGGATTATTTAATTTAAC	TTAAGGAGGACGAGGAATAATGGGCTATATGTTAATTG
GTTTCCGTCCCCCAATGAGGATTATTTAATTTAAC	TAGCACGATTCAAGATGTTTAATGTCATGTTGAATGGTAACGT
ATTTCCGTCCCCATCAGGGGATTATTTAATTTAAC	AATTCATCAATATGATGCGTTCATTTACAACGATGAACACAGT
GTTTCCGTCCCCATTAGGGGATCATTTAATTTAAC	ACAAGTCCAGGTGATTTAAAGATCGGAGACGCTACTCCGTTAAT
GTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC	GTTAGACCGACTAAATCGCTGATGCGGAGACCAGAGTTAATTC
GTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC	ATACATCAAATTTCTTTTATTGGTGTCAAGTTCGCCATAAAAA
GTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC	TGTTTCTTCAATTTGTTTATTCATATTAACTACCTTTCTATT
GTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC	TATATGGAATATACATATAGAACAATTCAAGATTATTTCTACAA
GTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC	ACGTTTACATAGATTTCTTTATCTGAATAGATTCTAGAAACTA
GTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC	GTACTTCTAACAATAGCTTCTTGATATTCATTATCTACCAT
GTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC	TTCAAATATTGTATTCCATAATATCAAATCAGAAATAGATGTAA
GTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC	GATAAAACGTGCGTATAAATCATTAGTTTTATTAAAGGAAGAAA
GTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC

>NZ_CP019721|8|7|565166-566267|PILER-CR
GGGGATTATTTAATTTAAC	GAAAAAGTAGAGGGTAAAGAATACAAAAAAATGGTATTCGTTTCCGTCCCCCAAT
GGGGATTATTTAATTTAAC	CATTAGCTGTAATTTCAATGATGACAACAGGAGTTGTCTTTGGTTTCCGTCCCCATCA
GGGGATTATTTAATTTAAC	TTAAGGAGGACGAGGAATAATGGGCTATATGTTAATTGGTTTCCGTCCCCCAAT
GAGGATTATTTAATTTAAC	TAGCACGATTCAAGATGTTTAATGTCATGTTGAATGGTAACGTATTTCCGTCCCCATCA
GGGGATTATTTAATTTAAC	AATTCATCAATATGATGCGTTCATTTACAACGATGAACACAGTGTTTCCGTCCCCATTA
GGGGATCATTTAATTTAAC	ACAAGTCCAGGTGATTTAAAGATCGGAGACGCTACTCCGTTAATGTTTCCGTCCCCTAAT
GGGGATCATTTAATTTAAC	GTTAGACCGACTAAATCGCTGATGCGGAGACCAGAGTTAATTCGTTTCCGTCCCCTAAT
GGGGATCATTTAATTTAAC	ATACATCAAATTTCTTTTATTGGTGTCAAGTTCGCCATAAAAAGTTTCCGTCCCCTAAT
GGGGATCATTTAATTTAAC	TGTTTCTTCAATTTGTTTATTCATATTAACTACCTTTCTATTGTTTCCGTCCCCTAAT
GGGGATCATTTAATTTAAC	TATATGGAATATACATATAGAACAATTCAAGATTATTTCTACAAGTTTCCGTCCCCTAAT
GGGGATCATTTAATTTAAC	ACGTTTACATAGATTTCTTTATCTGAATAGATTCTAGAAACTAGTTTCCGTCCCCTAAT
GGGGATCATTTAATTTAAC	GTACTTCTAACAATAGCTTCTTGATATTCATTATCTACCATGTTTCCGTCCCCTAAT
GGGGATCATTTAATTTAAC	TTCAAATATTGTATTCCATAATATCAAATCAGAAATAGATGTAAGTTTCCGTCCCCTAAT
GGGGATCATTTAATTTAAC	GATAAAACGTGCGTATAAATCATTAGTTTTATTAAAGGAAGAAAGTTTCCGTCCCCTAAT
GGGGATCATTTAATTTAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019721.1|WP_077707855.1|570256_571405_-|glycosyl-hydrolase-family-3	unknown	unknown	gnl|CDD|366376
NZ_CP019721.1|WP_077707852.1|563955_564726_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	gnl|CDD|273848
NZ_CP019721.1|WP_004694437.1|573572_573947_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077708641.1|557102_559247_-|TM1812-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	gnl|CDD|378186
NZ_CP019721.1|WP_077707849.1|549148_549568_-|DUF805-domain-containing-protein	unknown	unknown	gnl|CDD|377540
NZ_CP019721.1|WP_077707853.1|566631_567240_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707854.1|567559_568426_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NZ_CP019721.1|WP_077707850.1|555023_557042_+|hypothetical-protein	csx1	cd09732_csx1_CAS-III	unknown
NZ_CP019721.1|WP_077707848.1|547745_548744_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|376633
NZ_CP019721.1|WP_004698046.1|577379_579848_-|DNA-gyrase-subunit-A	unknown	unknown	gnl|CDD|235502
NZ_CP019721.1|WP_077707851.1|559388_561785_+|hypothetical-protein	unknown	unknown	gnl|CDD|379100
NZ_CP019721.1|WP_077707856.1|571818_573249_-|iron-hydrogenase-small-subunit	unknown	unknown	gnl|CDD|274171
NZ_CP019721.1|WP_077707858.1|575259_576615_+|MFS-transporter	unknown	unknown	gnl|CDD|129794
NZ_CP019721.1|WP_004698032.1|576929_577301_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_008601954.1|548758_549037_-|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|378256
NZ_CP019721.1|WP_008601959.1|547187_547553_-|hypothetical-protein	csx20	cls000118_csx20_CAS-I:CAS-III	unknown
NZ_CP019721.1|WP_187658829.1|552642_552843_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_077707857.1|574059_575157_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042
NZ_CP019721.1|WP_004694443.1|568716_569781_-|ATP-binding-protein	unknown	unknown	gnl|CDD|379062
NZ_CP019721.1|WP_077707847.1|545555_547157_-|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	gnl|CDD|274209

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP019721.1|WP_077707852.1|563955_564726_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	7.3e-17	56.8	0.1
NZ_CP019721.1|WP_008601954.1|548758_549037_-|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	1e-18	62.2	0.4
NZ_CP019721.1|WP_077708641.1|557102_559247_-|TM1812-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	4.2e-12	40.9	4.9
NZ_CP019721.1|WP_008601959.1|547187_547553_-|hypothetical-protein	csx20	cls000118_csx20_CAS-I:CAS-III	1.1e-58	192.0	0.0
NZ_CP019721.1|WP_077707847.1|545555_547157_-|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	9.6e-79	260.0	0.0
NZ_CP019721.1|WP_077707857.1|574059_575157_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	3.3e-11	38.4	0.0
NZ_CP019721.1|WP_077707850.1|555023_557042_+|hypothetical-protein	csx1	cd09732_csx1_CAS-III	3.4e-11	37.9	0.1
NZ_CP019721.1|WP_077707848.1|547745_548744_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	7.2e-75	246.6	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP019721.1|WP_077707855.1|570256_571405_-|glycosyl-hydrolase-family-3	gnl|CDD|366376	pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain.	4.47107e-31
NZ_CP019721.1|WP_077708641.1|557102_559247_-|TM1812-family-CRISPR-associated-protein	gnl|CDD|378186	pfam09455, Cas_DxTHG, CRISPR-associated (Cas) DxTHG family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. The family describes Cas proteins of about 400 residues that include the motif [VIL]-D-x-[ST]-H-[GS]. The CRISPR and associated proteins are thought to be involved in the evolution of host resistance. The exact molecular function of this family is currently unknown.	0.00192657
NZ_CP019721.1|WP_077707849.1|549148_549568_-|DUF805-domain-containing-protein	gnl|CDD|377540	pfam05656, DUF805, Protein of unknown function (DUF805). This family consists of several bacterial proteins of unknown function.	6.22624e-10
NZ_CP019721.1|WP_077707854.1|567559_568426_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	3.18865e-14
NZ_CP019721.1|WP_077707852.1|563955_564726_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl|CDD|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	0.000585577
NZ_CP019721.1|WP_077707848.1|547745_548744_-|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	4.40622e-95
NZ_CP019721.1|WP_004698046.1|577379_579848_-|DNA-gyrase-subunit-A	gnl|CDD|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0
NZ_CP019721.1|WP_077707851.1|559388_561785_+|hypothetical-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	0.00177802
NZ_CP019721.1|WP_077707856.1|571818_573249_-|iron-hydrogenase-small-subunit	gnl|CDD|274171	TIGR02512, Periplasmic_hydrogenase_large_subunit, [FeFe] hydrogenase, group A. This model describes iron-only hydrogenases of anaerobic and microaerophilic bacteria and protozoa. This model is narrower, and covers a longer stretch of sequence, than pfam02906. This family represents a division among families that belong to pfam02906, which also includes proteins such as nuclear prelamin A recognition factor in animals. Note that this family shows some heterogeneity in terms of periplasmic, cytosolic, or hydrogenosome location, NAD or NADP dependence, and overal protein protein length.	0
NZ_CP019721.1|WP_077707858.1|575259_576615_+|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.72685e-42
NZ_CP019721.1|WP_008601954.1|548758_549037_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	3.83589e-14
NZ_CP019721.1|WP_077707857.1|574059_575157_-|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	9.16581e-13
NZ_CP019721.1|WP_004694443.1|568716_569781_-|ATP-binding-protein	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	3.42348e-06
NZ_CP019721.1|WP_077707847.1|545555_547157_-|hypothetical-protein	gnl|CDD|274209	TIGR02578, CRISPR-associated_protein_Cas10/Csm1, CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2. A typical example is TM1811 from Thermotoga maritima. CRISPR are Clustered Regularly Interspaced Short Palindromic Repeats. This protein family belongs to a conserved gene cluster regularly found near CRISPR repeats.	3.09865e-05

Protein sequences

>NZ_CP019721.1|WP_077707852.1|563955_564726_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MSDNVEIMSIELVIVADLSIKIVQSIGSVLHGVLMELVGTEYAGQLHETGLRPYSQYIYFDKHKKQYIWRLSAVTADAVNRIVRPTLEMPEKIFLKQKRGYLYIKDRTILEETSYEALIHKFWSSDAFYSQTKLQCMSTTSFKVDQQYTIFPEAFRIYRYLLRQWNHFSTFGTMDADSLIDTFEKGVFIRDYNLRMGIYSLEGIKIRGFRGQIVMQFKRNIELQKILALLSYYSQFTGLGIKTALGMGGVKCEIIE
>NZ_CP019721.1|WP_077707851.1|559388_561785_+|hypothetical-protein
MYIFKRESIMATTTNYLNDLASMRQFIRSLTFGNHNRGKATVRGIKESQHDDVIRRLDYFDIIRHIYTQRIGKTSIHHLAKDDFVDGYNYLNNLYELYAAVPEQIYVQLCILSYIGANDDVTITDLYTNLNQEPYLDHYIDLVENLYEQRNKKQEPPCIIDQQYIQRQVKTLEILGAITKTELTKGYTYSIKPTIIEELSKQQLQELAMAVFFYTNVSITSAAGHILLKKIMYLINDFSLKDQQKCMYYDFNNTYFSFKDNNPNNVIDGDIFYPLADALHRQKKVRLSFYESGKPREIVSPLALQTYYGENKNMLCSINNGRIQWNRIDRIKSLEVTKYNSTNTVPQIQTKDKTFDTCIIHFLTLKDYDLVYDKFIRHFKESLTVLSSTDEYIELQLEVQDALQLLPQLRSYLPYVYITYTNKSSIKDKFYNNLYASLNIDFVEPEGYKKRKKINRFLHPLQRKESDNNKTKKDKDLDGTYVSSVLNDINAITFTTQYQLQLDLINGVVHTKQDIEGLINHRRLLTPAPYKKVLRNDDYEQFLADALVEPNENGEEVESILPDLPLVIISDAERMFLKDLISDTRANWLLSPELCQILSTELETVDTTFPRGSWTRVPTMTDDTPLTMQVITQCLQAIQNNERIMIQDKELSPCRIEYSVGSNGYTLIAYDHATDTFLDYPLRNESNIIKTAAPRLEDIETIYANYRDESKRTVTFTLYDANNAVDRCFNYFSNYTIQAKDINDEEFTIEVSYLPFQEIDILRHLLKLGCAVRITDDSPLKKQLETIYKTALIHAPSI
>NZ_CP019721.1|WP_077708641.1|557102_559247_-|TM1812-family-CRISPR-associated-protein
MAIHNIFLSFLSKVSNTSIKTIVNTDIEDAIRSSIATNESSLKYILYHTWKDEKTRDISFDKIYLLCTDGVMAHQSNSPSSYDIFVNQMCKFYNVMGHNEQAFFDALDHVPCGTDLDDISRIKSSIIEMSKKILDFKDTFTNDKDEVRLYMDITGGPRNAAMILLVISRLLAYHGIIVDDVYYSGYKEIENGPGEITVHKVLDIYELFDIIAGFEEFKLFGSAKKLNTYFKSPENIGTGNIESTATATKKLLKAMDSFSEAINISSRGAFEKSIARLDDSLSLVHSMANNTDNNKTFDQELIELLHKPIEQSYTTLLQHHRNHASDELAYIDWCLDHDYLQQALTLFCEYVPEYAVDKGIIKCDSLVFNAYYEDTQQNKEKRLLQAAIKAWNRAGNNIHFSTFYNVVMPDHDKKTSEKDARSMPMRLFNSINNARMQYLAAMINAKKDEVAPNIDKVITYYIKFVRNEKKKIQIVERDLQKQKERIHLMVDEETTKLREKCEVLLNQYGFTLYLQDDRYAENYTLLEYILFLQDILESVENIEAFNNILESLRKNIISEVLSKEEFKEYIICDADNSSFRLKKTSMLARNVVCNAILNHLIEEKKYKAYKSLIMHQLPDTKDSAVTAAELLLSQKKSNHRGVPLFEVSGVYIPHVLLDDIAKTMKFIEQYFEIKKARNDSNHANKEVLCKYTTSQELLDEMRKCVAMARELSRK
>NZ_CP019721.1|WP_077707850.1|555023_557042_+|hypothetical-protein
MEHHIYLTFLSTLHTKNNPYNPQKLEKTVVNLTEIAPFNVIRQTNESALKYLLHNKRKENSTFKLDKLFFFKSPEMENTFKESTISSLNVFEEQMCDYINKTSIPITWSPETINYIDCGDIDYIDNLKDSIIDMSQAIMEYYKSKSSDDRVILHVDLSGGPRTAIMLMIAIIRLVAFQGIEIGSILYANVNANNNSIVRVYEGNSIYNIYDMITGFAEFNQFGSVDTLKNYVNTLDNPDVQIKELISSMGDFSEAVRLSSRGIFQRSMEDIHKLLTDIESSKQEIPANNRENHKNFEIEALKLMSGKIQNNYKTVLANKEDDLAYIDWCLDNGYLQQALALFAEFVPRAILESKMIILDDTIFPTDSDNELSASMENFNTINEYTAKTMEIVNNRATKINNKIKSVLLKYFSGDFSKESKRIIKEVLKDKKNNTSTNITREDTQYPKFEEQLINDINQIILKEAEKEPHNYLKYKTFTNNNVNVPSKLLRLISNIGINTKSIVGINEFSKDIRRYFTAALVHQLKEIKDLPSDVVTVNDQYEITLNDTNKLFKVRDAFISIFTNSNNDDIYRFLFANFVSYQYPIDLFPHQLYGIDGLTLNSVLKSNPEKITQVARILNLYRTLKGSRNDTAHAREEKRGQFIESEDIKRELKQCLNDIRKVREYICTYNQQ
>NZ_CP019721.1|WP_187658829.1|552642_552843_-|hypothetical-protein
MQQYLLFTVLKQPDGPGFFESIILLQQYLPFTVCAEGCETAEEQSDDEVRTSQVPERSEGKTKVTK
>NZ_CP019721.1|WP_077707849.1|549148_549568_-|DUF805-domain-containing-protein
MIIKEGIMENLQQELKSMLSLSGRMNRRSYFMNLLMIIGIGYLGGLCISLAPVSKFFWVLGWSIIGYSVVRELAIASRRIHDLNGPTYLAGIYIVAAIIAIFEPTLAKIMGFVKIGLVLMPGDEDPNNYGERPDSMIVV
>NZ_CP019721.1|WP_008601954.1|548758_549037_-|CRISPR-associated-endonuclease-Cas2
MMRYLISYDISDTKIRNKVVKYLESFCYRVQYSVFLCVHAHVRVETIAKKLEVLTQGDETRRLLIVSISDTAKTPIWCNKMIPLTEDKMLII
>NZ_CP019721.1|WP_077707848.1|547745_548744_-|CRISPR-associated-endonuclease-Cas1
MMLETLYVMTPGISIRQDGGLLVLEKDHSVIKEIPIATVSNLVLGRTIQISTQVMFSLVKQGSLIQFVDHKYQLVGTLGDEHTTLQRLLWQVACFQNQEFALDGAKYIVRRKIKGQIALLNQYKKSKCIPNFVVVHRTMQALLKRVERTKKVDTLRGIEGLASRTYFSVLGHVLSEPWEFSGRKRHPSPDPVNAILSYGYSFLEREVRACLLTAGLDVRIGVLHSTNNRKDSLVYDVMDIFRQDIIDRFVLKLLNRHMMLPEDFDLSERGCFLSKETNKKWVELYEDYMKAELSRLDNLAPRKWIQQEIQAFISYLKSLGETVDIEKSENIS
>NZ_CP019721.1|WP_008601959.1|547187_547553_-|hypothetical-protein
MFINHTNHPSQYWSDEQLAAAHQYGEVVDIPFPLIDPALPSGEIGQLVQEYAGRIISLNPQAVLCQGEFVYCHALVERLLAVGITVLVATSERLVSESYEAGINEKIVNFQFVQFREYCHL
>NZ_CP019721.1|WP_077707847.1|545555_547157_-|hypothetical-protein
MQVNAILFDVQSIQKYIFANNKLKANVGASFIVDRLFEDVLCKEIINKLGVEADTTSWLTRSDSITSLPKTIYVAYIGGGNALVLIDDKHESLVQDIVKKFTTQVLVQYPGLKVGATTGYITLDGTQFSADLGKLYKQLKANQFALNPIVHPANTGLTTICDFSGDVADTTQSFGDEKRLVATSFTAKFEAFEAANSRLKIDLFGTETTDWVFPSEFEELGQNQSTEKSKTGINDIAIVHIDGNNMGAHFRQCKTLEERSALSKRVATKTLESFKALVQWIIDKYDILDENLELSKNMLPIRPIIIGGDDITFICNARIAVQASHYLMQQLLSDKNGISISSCAGIAVIPTSYPFFRGYEMAEQLCDSAKSKMREYNAVHKVNESCWMDFAFLHGETAPTLEQFFANEYSSLTGNMHFGPYQVFNDNIEAEKDIFALSKLLECTNQFILVKDKAYSGDLLAHNKVKELRSVLQDNEHMWTVFLEQLRNTNKFMPTVSGWDAFKEKLWAKVNGKMRTPYVDAIELMDYVLPGLE
>NZ_CP019721.1|WP_077707853.1|566631_567240_-|hypothetical-protein
MAIDDKPTDLMAARLSKGEDLDLIYTNPKNHIVCFIPTYQPSGGDSTKCYFVDGREEMVHLPMRTITRELAMQEGLRPNYIMTSDGRRSSYTAPKTYGPHLTFAHIKCRRPIGKDVVYGLFNVAIPYEYIVTEGPEPDTSYIHVADFAPILVYQSPRHVKHKLNEAMLEHCNYVRKMLARIKLSQNPQVVAELFIAWRDLTR
>NZ_CP019721.1|WP_077707854.1|567559_568426_-|sigma-70-family-RNA-polymerase-sigma-factor
MLYTNEEPLVQKICIKTANLQHDNYQSETLETQALPSHSLLSKADESTRSIPEELKLQTLVCGHQVLSSLSDKSLVSICQKPNMRIQTVGYQPWSVDELRHDAAQIELCRRYRPLILHYTNRMGNREFREDVESYLWAILIESIYSFDLNGTVPFPGFVKAGIMYGYMRYWKRERLRYHREIHIPDRTTDDGEVAFGMDIFASGENVADMVMSADEEHRLRARLVWALGRLSPDQRDLLRRVYGECQSLVSVSEELNCSRQAIQRRHERAIRKLRRYLSTDFKDVRVH
>NZ_CP019721.1|WP_004694443.1|568716_569781_-|ATP-binding-protein
MNFVGRAEIIERIQSRIAMGQMSLCVVYGPHRSGKSYVASQLVRRHKAIYLAGRMANESVHVADINRALEARFVPANAQDTFEPVESLQQAFVRLFESSVKTPQTVVIDDYPSLVEAVPQFPIHLRDLLDTYKDTSRLNIILMANGLEQLDGRIIGDRSLIGPFVSEYLEVKPFSLVDMKSLGLHYAKDDLRTVFAVTGGLPAYVQYFDNGESIDTNIINLFFSVTGALFEETQYILHRDMKNITGANAILTGLASLERPYYVELLQESQIKSGTFTSRLNDLMSMGLVGRIQASNRGNAKYADYHFTNSMFHFWYRYVYKYWGDIVRGYGADVYYNHVKPQLKDFVQAACIAI
>NZ_CP019721.1|WP_077707855.1|570256_571405_-|glycosyl-hydrolase-family-3
MNQFFRRVLSGLALLVAVVGTTGCQHESQAEQETVRTVSYRAVLESNKPVSEKVDTWIAAMSQEDKVGQLMMISLHGSTIGQSQKDVIRKYRVSGVMLTNENLINKNQVKTFTSDIMQTAITSSMVTPYIAVYRDRILHGNESFLRLPKPNRWGQLPMDRIINLATRSAIEMRDMGFNLVIGPNANLGVPNMSYTSDPTWAGHINLAMVERYQINHMWSAYNYFPAVTLGDASFGSANEAKAYLSNNDVAVFKRLIAQTTANSYMLVMSHIQIPAIDNEHLASSSKPIIDGWLRKELGYKGIVMTDRIDVGALQSNQKIGDYAVASILAGSDLILVDADTIHIDEVHRALTQAVADGTITTERLNESVKRILLMKMQTQMDP
>NZ_CP019721.1|WP_077707856.1|571818_573249_-|iron-hydrogenase-small-subunit
MSQYEFIDKRVPIALDNPSIYHDISKCKNCTLCRRACADVMSVLDYYDLDANGDVPVCIHCGQCAAACPFDSMHAKSELEKVKAALADPEKIVVIQTAPAVRVSIGEGFGYEPGTFLEGKMVGALRKLGADYVVDTNFGADLTIMEEASELVERLKNGGQIPQFTSCCPAWVRFAEIYFPELIPNLSSTRSCIAMEAAMIKTYFAEKKGIDPRNIVSVSVNPCTAKKAETKREEENAAARYHNDESLGMDTDISITTREFIRWIQEEHIDFNTVEESQFDDLIGMETGASIIFGNTGGVMEAALRTAYKLITDKEPPPYALTHLEDVRGMEGVKEATVQLGDDVTLSVAVVHGGKNTRDFLNALKDSGKHYDFIEVMACPGGCIGGGGQPRTKLPQAVKTKEARIGGLYEADENYKWVASYENEEIQTLYKDFLGEPLGHKAHELLHTHYTDRSAVLGTRKDVTPETCPTSPKFKG
>NZ_CP019721.1|WP_004694437.1|573572_573947_-|hypothetical-protein
MKKTLAAVLAAGALLIGGIGSVDAANWYTVGTDSNGVTWSIDNDSVKKDDKKAVMDIKAMDYEGYHYIVTEEFNHKKREVKDLKVTLYNPQGYVVKEEQVNKNSRKVEPGTPAYAVFQLIWGGK
>NZ_CP019721.1|WP_077707857.1|574059_575157_-|winged-helix-turn-helix-transcriptional-regulator
MSITIRFSDYALETNETLIQRIQFVYSPLNELFRSLHVLLNPRHHGTNIDWVIEIQDKLTEEFYENLHYFQLFYELGVSPILLCNFRYHMTTIEEEIQNLKKFLVNYPTIQLIEYLERIIDDRENAFIPTLAKGLEWKDFSLNENDQLLKDLKRNATSVYRRFFSFIDWYRKSIFDDTWKEKSIEQKLLIEIQKQSSFLREKGFIEMFNHLQIDRIHWEKGALAIIKPFNQEVYLKDSDSIMLLPSYFIWPHLFVESFNQGIAITYDIAEQPSYYNSTPEGLVTIFKALSDSVRLQIMNYVLEKPSTTQSLAQILLMTESSVSRHLQILKDAKLLKARKVKKFVLYEPTELVTQLMPNFYRFFRN
>NZ_CP019721.1|WP_077707858.1|575259_576615_+|MFS-transporter
MNKQLQDLLITIVAGMGMLLSTLDTGIINIALPFLKEQFQTSTDIAAFTITGYTLALAISILPLGVLSDKFGKLKISYLGFVLFGLSSLFCGLINNISLLIIGRIFQGIGAAALQATSAALITTLVSEKRKNSSIGILGIMIGLGPILGPSLGGIILSLSFWQLIFLINIPFVILGIACNNFLLNKLSEKNNNRQLDMLGITINTLMLVSLLLGLSLLNKSHLFVVGIILILSSLLLGIIFYYMELKNKHALIDIKGLKNNPQVISYLFQTVTFGFASAMIFLLPPFIFEQSYHLEVGQTGFLVLGAPTGLVLFSRISSKINNGNKNKLFSHIGLSIIIISLIFLLLINPNWPYQLLTLGLFIYGIGGGYFQPANIASIMQASPMEIQGSTGALQRMLQNVAISIGSAIGATCLNIWSNDLLLATRIGWGITLILVIISLKEVFKFSHHNS
>NZ_CP019721.1|WP_004698032.1|576929_577301_-|hypothetical-protein
MKKWLAAMFAAGVFFVGGFGQASAADWYYIDADADDAAWFIDNSSVYKTDDAATVLVKINNVEGFTYIYTVRIDRKEKTWTELDTTVYSNAGIALLSSKQAQKPTKIEPDTMGAEVMQALWGK
>NZ_CP019721.1|WP_004698046.1|577379_579848_-|DNA-gyrase-subunit-A
MADQQWSHGNIHPVQIDKEMKNAYIDYAMSVIVMRALPDVRDGLKPVHRRILYAMHETGMTPNKPYKKSARIVGDVLGKYHPHGDSSVYDATVRLAQDFNTRYLLVDGHGNFGSIDGDSAAAMRYTEVRMAKITTEMLADIDKETVDFMPNYDESLQEPTVLPAKIPNLLINGSSGIAVGMATNIPPHNLNEVCNGLAMLIDNPDVTVDELMTAIKGPDFPTGALILGREGIKKAYSTGRGSVKMRARATIEEMSKGKHKIVVTEIPYQVNKARVIETIANLSRDKVIDGITALRDESDRQGMRIVIELRADVQPDIVLNKLYKHTQLQETFGVIMLALVDGHPRVLNLKEVLGYYLDHRLDVIVRRTQFELNKAEARAHILEGLLIALDHIDEVIATIRSSQTDEIARNALMQKFGLSEKQAVAILDMRLRRLTGLEREKIEEEYKELLALIEDLKAILASEARQRQIIKDELDDMKKKYGDPRRSEITIDTSDLDVEDLIADEEMVITLTKQGYIKRMNANVYRNQHKGGAGVIGMKTKEDDYVTQIMHVRTHNTLLFFTSAGRAYRLKAYEVPEAGSRNSRGTAMVNVLPLAVGESVTTMIDLERVHEDVNLFMVTEFGVVKRTAIEEYRNIRRSGLNAINLDEGDRLISVNVTTGNQDILIGTKLGIAIRFSEHDVRLMKRAAHGVRGIKLNAGDVVVGAGVLNTDESEAQVFTISEEGFGKRNDAEAYTLQKRGGKGSKNFKITNKTGDVVAVEVVHNDDEVMLISEQGKIIRFNMNDIAVKKGKAISGVKTQNLDEGDKVASIAVIPGAEIEEEVE

Crispr_ID: NZ_CP019721_9

• CRISPR_ID: NZ_CP019721_9
• CRISPR_location: 1180195-1180304
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP019721_9

Consensus_repeat	Method
AAAACTGCAATTGATAAAAATACTGG	CRISPRCasFinder

spacers of NZ_CP019721_9

>9.1|1180221|58|NZ_CP019721|CRISPRCasFinder
TGATATTGCAACAAATAAAGGAGATATTGCAGCCAATAAACAAAAAATAGCCGACAAT

CRISPR arrays and Neighbor proteins around NZ_CP019721_9

CRISPR arrays

The CRISPR arrays of NZ_CP019721_9

>merge|NZ_CP019721|9|1180195-1180304|CRISPRCasFinder
AAAACTGCAATTGATAAAAATACTGGTGATATTGCAACAAATAAAGGAGATATTGCAGCCAATAAACAAAAAATAGCCGACAATAAAACTGCAATAGATAAAAATACTGG

>NZ_CP019721|9|8|1180195-1180304|CRISPRCasFinder
AAAACTGCAATTGATAAAAATACTGG	TGATATTGCAACAAATAAAGGAGATATTGCAGCCAATAAACAAAAAATAGCCGACAAT
AAAACTGCAATAGATAAAAATACTGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019721.1|WP_077708211.1|1173083_1174280_+|divalent-metal-cation-transporter	unknown	unknown	gnl|CDD|224826
NZ_CP019721.1|WP_077708212.1|1174354_1175098_+|5-oxoprolinase-subunit-PxpB	unknown	unknown	gnl|CDD|367142
NZ_CP019721.1|WP_077708210.1|1169594_1170695_+|2-iminoacetate-synthase-ThiH	unknown	unknown	gnl|CDD|236425
NZ_CP019721.1|WP_021147832.1|1167287_1168592_+|phosphomethylpyrimidine-synthase-ThiC	unknown	unknown	gnl|CDD|376689
NZ_CP019721.1|WP_021147837.1|1171346_1171994_+|thiamine-phosphate-synthase	unknown	unknown	gnl|CDD|238317
NZ_CP019721.1|WP_021147838.1|1172174_1172942_+|5-oxoprolinase-subunit-PxpA	unknown	unknown	gnl|CDD|212099
NZ_CP019721.1|WP_051147513.1|1170701_1171343_+|sulfur-carrier-protein-ThiS-adenylyltransferase-ThiF	unknown	unknown	gnl|CDD|236320
NZ_CP019721.1|WP_077708214.1|1175084_1176107_+|biotin-dependent-carboxyltransferase-family-protein	unknown	unknown	gnl|CDD|224895
NZ_CP019721.1|WP_077708221.1|1194468_1195215_+|ubiquinone/menaquinone-biosynthesis-methyltransferase	unknown	unknown	gnl|CDD|234689
NZ_CP019721.1|WP_077708217.1|1185817_1187227_+|MATE-family-efflux-transporter	unknown	unknown	gnl|CDD|240542
NZ_CP019721.1|WP_077708222.1|1202726_1203587_+|polysaccharide-deacetylase-family-protein	unknown	unknown	gnl|CDD|213023
NZ_CP019721.1|WP_004692958.1|1195195_1195927_-|SIMPL-domain-containing-protein	unknown	unknown	gnl|CDD|225516
NZ_CP019721.1|WP_021147833.1|1168615_1168813_+|sulfur-carrier-protein-ThiS	unknown	unknown	gnl|CDD|340451
NZ_CP019721.1|WP_004692962.1|1190292_1190949_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_021147834.1|1168814_1169585_+|thiazole-synthase	unknown	unknown	gnl|CDD|234687
NZ_CP019721.1|WP_077708220.1|1191138_1192656_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|235774
NZ_CP019721.1|WP_004692960.1|1192901_1194122_-|serine/threonine-transporter-SstT	unknown	unknown	gnl|CDD|184190
NZ_CP019721.1|WP_077708219.1|1187779_1188817_+|OmpA-family-protein	unknown	unknown	gnl|CDD|143586
NZ_CP019721.1|WP_077708224.1|1203595_1204090_+|MogA/MoaB-family-molybdenum-cofactor-biosynthesis-protein	unknown	unknown	gnl|CDD|238451
NZ_CP019721.1|WP_004692963.1|1189043_1190165_+|AI-2E-family-transporter	unknown	unknown	gnl|CDD|223701

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP019721.1|WP_077708211.1|1173083_1174280_+|divalent-metal-cation-transporter	gnl|CDD|224826	COG1914, MntH, Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism].	4.46029e-67
NZ_CP019721.1|WP_077708212.1|1174354_1175098_+|5-oxoprolinase-subunit-PxpB	gnl|CDD|367142	pfam02682, CT_C_D, Carboxyltransferase domain, subdomain C and D. Urea carboxylase (UC) catalyzes a two-step, ATP- and biotin-dependent carboxylation reaction of urea. It is composed of biotin carboxylase (BC), carboxyltransferase (CT), and biotin carboxyl carrier protein (BCCP) domains. The CT domain of UC consists of four subdomains, named A, B, C and D. This domain covers the C and D subdomains of the CT domain. This domain covers the whole length of kipI (kinase A inhibitor) from Bacillus subtilis. It can also be found in S. cerevisiae urea amidolyase Dur1,2, which is a multifunctional biotin-dependent enzyme with domains for urea carboxylase and allophanate (urea carboxylate) hydrolase activity.	9.06673e-94
NZ_CP019721.1|WP_077708210.1|1169594_1170695_+|2-iminoacetate-synthase-ThiH	gnl|CDD|236425	PRK09240, thiH, 2-iminoacetate synthase ThiH.	0
NZ_CP019721.1|WP_021147832.1|1167287_1168592_+|phosphomethylpyrimidine-synthase-ThiC	gnl|CDD|376689	pfam01964, ThiC_Rad_SAM, Radical SAM ThiC family. ThiC is found within the thiamine biosynthesis operon. ThiC is involved in pyrimidine biosynthesis. ThiC participates in the formation of 4-Amino-5-hydroxymethyl-2-methylpyrimidine from AIR, an intermediate in the de novo pyrimidine biosynthesis. Thic is a member of the radical SAM superfamily.	0
NZ_CP019721.1|WP_021147837.1|1171346_1171994_+|thiamine-phosphate-synthase	gnl|CDD|238317	cd00564, TMP_TenI, Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5- (beta-hydroxyethyl) thiazole phosphate to yield thiamine phosphate. TenI is a enzymatically inactive regulatory protein involved in the regulation of several extracellular enzymes. This superfamily also contains other enzymatically inactive proteins with unknown functions.	6.14154e-70
NZ_CP019721.1|WP_021147838.1|1172174_1172942_+|5-oxoprolinase-subunit-PxpA	gnl|CDD|212099	cd10787, LamB_YcsF_like, LamB/YcsF family of lactam utilization protein. The LamB/YbgL family includes the Aspergillus nidulans protein LamB, and its homologs from all three kingdoms of life. The lamb gene locates at the lam locus of Aspergillus nidulans, consisting of two divergently transcribed genes, lamA and lamB, needed for the utilization of lactams such as 2-pyrrolidinone. Both genes are under the control of the positive regulatory gene amdR and are subject to carbon and nitrogen metabolite repression. Although the exact molecular function of LamB is unknown, it might be required for conversion of exogenous 2-pyrrolidinone to endogenous GABA.	8.22068e-140
NZ_CP019721.1|WP_051147513.1|1170701_1171343_+|sulfur-carrier-protein-ThiS-adenylyltransferase-ThiF	gnl|CDD|236320	PRK08644, PRK08644, sulfur carrier protein ThiS adenylyltransferase ThiF.	3.10499e-84
NZ_CP019721.1|WP_077708214.1|1175084_1176107_+|biotin-dependent-carboxyltransferase-family-protein	gnl|CDD|224895	COG1984, DUR1, Allophanate hydrolase subunit 2 [Amino acid transport and metabolism].	1.40475e-110
NZ_CP019721.1|WP_077708221.1|1194468_1195215_+|ubiquinone/menaquinone-biosynthesis-methyltransferase	gnl|CDD|234689	PRK00216, ubiE, bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE.	1.44245e-98
NZ_CP019721.1|WP_077708217.1|1185817_1187227_+|MATE-family-efflux-transporter	gnl|CDD|240542	cd13137, MATE_NorM_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	1.47114e-86
NZ_CP019721.1|WP_077708222.1|1202726_1203587_+|polysaccharide-deacetylase-family-protein	gnl|CDD|213023	cd10918, CE4_NodB_like_5s_6s, Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands. This family belongs to the large and functionally diverse carbohydrate esterase 4 (CE4) superfamily, whose members show strong sequence similarity with some variability due to their distinct carbohydrate substrates. It includes bacterial poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, hemin storage system HmsF protein in gram-negative species, intercellular adhesion proteins IcaB, and many uncharacterized prokaryotic polysaccharide deacetylases. It also includes a putative polysaccharide deacetylase YxkH encoded by the Bacillus subtilis yxkH gene, which is one of six polysaccharide deacetylase gene homologs present in the Bacillus subtilis genome. Sequence comparison shows all family members contain a conserved domain similar to the catalytic NodB homology domain of rhizobial NodB-like proteins, which consists of a deformed (beta/alpha)8 barrel fold with 6 or 7 strands. However, in this family, most proteins have 5 strands and some have 6 strands. Moreover, long insertions are found in many family members, whose function remains unknown.	1.62856e-53
NZ_CP019721.1|WP_004692958.1|1195195_1195927_-|SIMPL-domain-containing-protein	gnl|CDD|225516	COG2968, COG2968, Uncharacterized conserved protein [Function unknown].	6.4365e-42
NZ_CP019721.1|WP_021147833.1|1168615_1168813_+|sulfur-carrier-protein-ThiS	gnl|CDD|340451	cd00565, Ubl_ThiS, ubiquitin-like (Ubl) domain found in sulfur carrier protein ThiS. ThiS, also termed Thiamine biosynthesis protein (ThiaminS), is a sulfur carrier protein involved in thiamin biosynthesis in prokaryotes. It has the beta-grasp ubiquitin-like (Ubl) fold with low sequence similarity to ubiquitin (Ub), and is activated in an ATP-dependent manner by sulfurtransferases, similar to the activation mechanism of Ub-activating enzyme E1. ThiS has common evolutionary origin with Ub-related protein modifiers in eukaryotes, a beta-grasp fold as Ub, and is closely related to proteins MoaD and Urm1.	8.89718e-17
NZ_CP019721.1|WP_021147834.1|1168814_1169585_+|thiazole-synthase	gnl|CDD|234687	PRK00208, thiG, thiazole synthase; Reviewed.	2.83468e-144
NZ_CP019721.1|WP_077708220.1|1191138_1192656_-|FAD-dependent-oxidoreductase	gnl|CDD|235774	PRK06292, PRK06292, dihydrolipoamide dehydrogenase; Validated.	7.16502e-130
NZ_CP019721.1|WP_004692960.1|1192901_1194122_-|serine/threonine-transporter-SstT	gnl|CDD|184190	PRK13628, PRK13628, serine/threonine transporter SstT; Provisional.	0
NZ_CP019721.1|WP_077708219.1|1187779_1188817_+|OmpA-family-protein	gnl|CDD|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	4.97394e-29
NZ_CP019721.1|WP_077708224.1|1203595_1204090_+|MogA/MoaB-family-molybdenum-cofactor-biosynthesis-protein	gnl|CDD|238451	cd00886, MogA_MoaB, MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea, and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MogA, together with MoeA, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes. In contrast, MoaB shows high similarity to MogA, but little is known about its physiological role. All well studied members of this family form highly stable trimers.	1.61805e-59
NZ_CP019721.1|WP_004692963.1|1189043_1190165_+|AI-2E-family-transporter	gnl|CDD|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	6.96798e-40

Protein sequences

>NZ_CP019721.1|WP_077708214.1|1175084_1176107_+|biotin-dependent-carboxyltransferase-family-protein
MDINEFQRALIRVDAPGMYTTIQDIGRIGFQQYGMPVAGPMDSESYLLGQALVGNKEPLGALECTVLPPTLTVQGTCIVAFTGADMHPTINNVVVPRYIPFICHEGDIISGGFSQCGVRMYIAFSGGVDVPAINGSVSTHTKAKIGGFEGRSLQAGDQFGIKAFTRHEVNVCDFYGTHKLFNTALYNRGGRECHEPLRVVLGEQAKYFTEKGIKTFGSKIYTLTVQCDRMGFRLDGPVIEHIDSADIISDGAVFGSIQVPSDGNPIVLMADRQTTGGYTKIGTVITADLPRLSQLPVGDGIHFDIISVEEAQEIYRTYIRHLHKRIELAHEQSLYVFKVS
>NZ_CP019721.1|WP_077708212.1|1174354_1175098_+|5-oxoprolinase-subunit-PxpB
MKPTISPVGDCAISIDFGQVIDPKINRHIRQIIEQIKDLQLDGIIELVPTYCALLVQYDAMVYSYSDICRILEPTLQESVTDSANELVTIVEIPTVYGGEFGPDLGFVASYNHLSEAEVVSIHSGTDYLVYMLGFIPGFTYLGGMDPRIATPRLSSPRTLIPAGSVGIAGEQTGTYPSDSPGGWQIIGRTPVTMYDMSKEQAALLQAGDYVRYVSIDENEFHRVKSLGMEYIPSIYEIESGDLRGYK
>NZ_CP019721.1|WP_077708211.1|1173083_1174280_+|divalent-metal-cation-transporter
MKPITGKASFSVLLGAAFLMATSSIGPGFMLQTAAFTNELKADFAFAIVVSVIFSIIAQLNVWTIIGVSQMRGQDIANKVLPGLGYIVAFLISLGGLAFNIGNIGGASMGLNIIFGIDTTTAAAISGILGILLFTSKKMGGVLDNTAKVLGTVMLVLIAYVAFSTNPPVGEALSHSVIPEHVPWLATITLIGGTVGGYITFSGGHRLIDAGITGQEHLKDVRRAAIMGMSVDALVRVLLFLAVLGVVSMDFVLDSKDPAGSAFLLGAGEIGHKLFGIVFFCAALTSVVGAAYTSVSFLKTLFKIVERNEKLTIMAFIFISTCILIFIGKPVSLLILAGSVNGLILPVTLAVMLVATHKSEIVGTYKHNKLLYYTGWIVVLVTSYIGVTSLKGIAKLLG
>NZ_CP019721.1|WP_021147838.1|1172174_1172942_+|5-oxoprolinase-subunit-PxpA
MSHYVDLNSDLGESFGNYTLGMDSEVLNHVTSANIACGWHAGDPLIMDATVRICKEKGVAIGAHPGYPDLMGFGRRAMAVNPAEAKAYMMYQLGALQAFCDSYDITLQHMKLHGAFYNTACVTPVLADAILDGLQAVNPNIAAMVLSGSYIAQEAQRRGIPVIQEVFADRGYTEEGTLVPRTEVGAFIKDPQEALDRVLMMVTKGKVVTNTGKTIDIVADSVCVHGDNPEAIAFTRYIREGLIKAGVTVANFQHR
>NZ_CP019721.1|WP_021147837.1|1171346_1171994_+|thiamine-phosphate-synthase
MNRKDKLTEVINACPIYGITGGTRDVVTLVKDMLSAGIRIIQYREKGKTPILRYQEAMILRRLTYDYHALLIIDDYVDLALAIHADGVHIGQDDLPPNTVRRIVGPNMLIGWSTHSISDLKAANRYTSVIDYIGVGPIFSTQTKPNANPVGISYVYWAKQFSKVPIVAIGGIKTTNADIVWQAHPDFICAVSEITESDNIQNTVYELMTGYSRVR
>NZ_CP019721.1|WP_051147513.1|1170701_1171343_+|sulfur-carrier-protein-ThiS-adenylyltransferase-ThiF
MCMAHMNNEFETAISHFYSPEEFRKLQNSVVGIIGAGGLGSNCAVNLVRSGIRNLIVADYDIVELSNLNRQHYFSCHVGQYKVEALQDVLTALNSNVIVKIYKDKLTTENIPEIYKKADILIEAFDAVEAKSMFLEAATSVDVPKIMVSGLAGIGNSDALRTKKLGQNLYIVGDEHSGVDNAYPYAPRVAIAAAKQADLALSLLLEKTMSNEV
>NZ_CP019721.1|WP_077708210.1|1169594_1170695_+|2-iminoacetate-synthase-ThiH
MSFLDVLSRVSDEDIAETLEAITGDEILSTLSKPALAIDDALILLSPQALLYLEDMAQLAHEQTVQQFGYTIQLFTPMYISNYCDNGCVYCGYSHHSGIAREKLSLNDIELEAKAIAETGLEQVLVLTGESKSCSPPAYIQAAVETLVPIFSSVSIEVYSLTLEEYKGLVAVGADGMTMFQETYNPTLYAQLHPFGPKSGFAKRIDTPELACQAGFRVVNIGALMGLDEWRREAYKTMLHLNYLVQHYPDVELSVSVPRIRPCAVGYSPKYPVDDTALVQYILALRLLFPRVGITLSSRESKYMRDNLVRLGITKLSAGVTTSVGGHTKQDDSSQFTISDNRSVSEMAVMLENNGYQPIYKDWQTL
>NZ_CP019721.1|WP_021147834.1|1168814_1169585_+|thiazole-synthase
MLDSFTVGNTTFSSRLLVGTGKYASYNLMRDALVASKSDIVTVALRRAGTTQSEEDILNYIPDRMHLLPNTSGARNADEAIRIARMARELGCGDLIKIEVIQDQMYLMPDNLETIRAAEVLAKEGFIVFPYMSPNLMDAKRLVDAGASCIMPLASPIGSNRGLEAKGLIEILINSIDVPIIVDAGIGRPSDATIAMEMGASAVLVNTAIATSSNPVGMAEAFYYAVEAGRKAYLAKCAPKKSVGSASSPLTGFLRK
>NZ_CP019721.1|WP_021147833.1|1168615_1168813_+|sulfur-carrier-protein-ThiS
MDLIVNGEPKYVVGEQLHLILDELGYSGKHFVVELNGEILSKEAYTTTKLTAADRLEIVSFVGGG
>NZ_CP019721.1|WP_021147832.1|1167287_1168592_+|phosphomethylpyrimidine-synthase-ThiC
MFMTQLESAVAGVVTKEMKVVAEKERMDEEVLRSLVAAGKVVIPCNKQHTSISPEGIGKRLRTKVNVNLGTSKDVTDYDSEIEKVNRAIRLGAESIMDLSTHGDTRIFRRKLIETSPVMIGTVPIYDSVIHHQKDLGELTAQDFLDTIRLHAQDGVDFITIHSGITRKTIDQIKNHKRLLNIVSRGGSLVFAWMSMTGHENPFYEYFDEILKICKEYDVTLSLGDACRPGCLADATDVCQIEELVRLGELAKRAKQYGVQAMIEGPGHVPLHQIQMNMEIQESLCDGAPFYVLGPLVTDIAPGYDHITAAIGGAVAGMYGASFLCYVTPAEHLALPNADDVKDGIMAFKIAAHAADIARGIPNARDIDDTMAKARQVLDWEAQYACALDPERARSIRESRAPEEDHGETCSMCGKFCAVRSMNKALQEEYIDIL
>NZ_CP019721.1|WP_077708217.1|1185817_1187227_+|MATE-family-efflux-transporter
MLDRIQRWLSVDTMLPVAERLGPVGTTKQLYGNYLKIAWPATLQGLMLQFMTAIDLAMVGALGASALASVGIMGQPEMVMLIFCRALSIAVTAIIARRHGEGGVDGMNAVLKQSILLNFLIYVPLLLICFLNLEHILRFTGAEDGYIETAVWYGRFIVISLIFQSFSQIVGAALIGYGNTKVIFKSNVVGNILNTIMNFFLIYGIGFFPELGVMGAGVSTMISSAIIALLLLRTISQHTSTGLTLRHPSKWTFERPVLHTMFHVGGSSLGEQFFERFGMYTYTMIVASLGAVPLAAHYVCMNLMDIFYYFAMGLGFAGASHTGQSLGHKRPDIARTYGKIGARIGLVVGLVSALIFMGPGDFLVQLYTRESDVVTLSATLMGIMAIAAFPQALQQVYSGVLKGAGDTYYIMKYSLVSVAIIRPIITYLLCITLGLGLFGAWLSLCFDQSLRLCCSYLRFIRGTWQHKVV
>NZ_CP019721.1|WP_077708219.1|1187779_1188817_+|OmpA-family-protein
MNKKLLALLAVAAVGVSVAGATPQTQFNKGEFQVNLGASDSKAKTKAWTSDAKWNFDGGVTYAFTDKTALQYQYHGLNDKMFGTSYSDRMQEVNLIQSLNKNFAVYGGYAHISGDTFPKANNIAQLGVIGKANLGSKVDVYGKAGVGTKRTTTWEAGLGYKVNQDWDINAGYRYINTKRDDKSNISFQGPVVGLSYRFGGHKSVAPVYTPAPAPVYTPAPAPTVEAPAYKTPKLDYYVQSIYFDSDQDVARADQYPNLTAAVNAANQYSQDQVKLMGNADTDANPQYNIALSERRVQHVAQYLVNHGVSADRLIGIANGDVKPVATNSTAAGKAENRRVDVYIHR
>NZ_CP019721.1|WP_004692963.1|1189043_1190165_+|AI-2E-family-transporter
MKEFKYYKQLIGAIILAGIMIMMALRISDIASGLDAIFTAFVPLIVGACIAFVLDILVVRYERWLWPKCGSGWKYKIRRPLSLLLSFVTISVIVYFIARMALPQLIHSMSIIVAASPQLYTDFQTWMQHITETVPMASNQTIIDALSGENIAKYTREWGTKGGTYIVNAMGTVLSWTLNIGLGLIFAVYMLLDKERLMLQGKRILKAYASDEWVNRVSYVTRVAVQTFSNFFVGQFIDALVLGVMVGITLWLFNIEYATTIACVIGLTGLIPLLGIYVGGIIGAVMLLTVSPMDALIYVIILEVLHQIESNFIYPKIVGNSVGLPGLWVFAAVIVGGSLMGVTGMLIGVPLVATCYKLIMTDVDGRLASNEGL
>NZ_CP019721.1|WP_004692962.1|1190292_1190949_+|hypothetical-protein
MNKKLISMALTGVLAVGMLSVATPSVADARKTKPETSTDISVKRAPGESIVMTMSQIGTIFQNRYPNAALHSVELNSNDLNYGYKVVGYSKYHQYKMKIDVITGNASDMEEGGKPKKVIGEIFNKDKVIESTQAERVAKQQLGNDAVMKGWKIEAHNGKVLYYVTMHQDGKKVVVTVDAETGAYVEQSKSYKLPPEPDQGFDGRKTNLVWGSDIDMGR
>NZ_CP019721.1|WP_077708220.1|1191138_1192656_-|FAD-dependent-oxidoreductase
MKQYDIIVVGTGGATIVADAALKKGLKVAIIEKGKFGGTCLTRGCIPTKVMVTAANAIQETKEFKKIGVNVGPATMDWHTVSKRTWHKIDESAGIYDYYNAYDNVDVYRGAASFVSDKVMNIHLNDGSGIVEITAPTIILGTGGYSNVPNVPGLQESGFLTSESLFGDKFPKQPYKSLAVLGAGPIGVEFAHVFDSAGTKVTILQHNVRLVPKEDADISEHLLNNYRERGINVLLNQDTVEIRQEDGLKVVVTKDRTTGEITETKVEEILVAAGIRPAVEELHLENTGIETRPKGWIKTNEFLETSVDGIYALGDVNGEPAFRHRANYEADIIAHNLFYATSEDDYRWARYDTLPKVTFSYPEIGSVGLTEAEAIKAGYNVGVGKNFYSSTAKGYAMGINPGDVNDGFVKIVVDKDTNHILGMHVVGPQASILFQPYVNLMNSGVTPLTAINEEIASERTKRLREKGITREMDPRSVITVGETMSPHPSLVEVIMWTQVYYENRW
>NZ_CP019721.1|WP_004692960.1|1192901_1194122_-|serine/threonine-transporter-SstT
MNRFVKSINRVSLIQQIIIGLIIGILTALYVPDVANELALLGVLFVGALKGIAPILVFFLVIAAISKHRSGQKTGMGSVITLYLLGTFLSAALAVIVSFFFPTTLHLAAGAADAAPPQGIVEVMTTLLKNVVDNPVKALMTANYIGILGWALIIGGALRHAPMNTKEVMESIAQAITTVVGWIIRFAPLGIMGLVAESIATNGIEALIGYFQLLVLLLGSMIFVALVINPILSFIYLRRNPYPLVFKCLRESAIYAFFTRSSAANIPVNLDLAKRLKLNPDMYSVSIPLGATINMGGAAITITIMTLAAAHTLGIVVDIPTAILLSVIATIGACGASGVAGGSLLLIPLACSLFGISNDVAMQVVGVGFIIGVLQDSTETALNSSTDILFTATADYAKRGYHQDWN
>NZ_CP019721.1|WP_077708221.1|1194468_1195215_+|ubiquinone/menaquinone-biosynthesis-methyltransferase
MNTKEFKTYADKEKFVQGVFSNIAKNYDLMNTVLSFGQDYFWRKFSVKAMNIGPHQYVLDVACGTCVFTKEALCQEPTLKVEALDFNSEMLNQGRVRIEAAGLLNQVNLVQGDAMALPYEDNTFDAAMSGFAMRNVPDIKQVLSEMQRVVKPGGKVVVLELAKPSMFGFKQLYNFYFSYILPIIGKLSKDNSSYAWLPESLRRYPHQSEILEIWKSLGYENATYHELTGGIVAVHEGVVPENSIVDNK
>NZ_CP019721.1|WP_004692958.1|1195195_1195927_-|SIMPL-domain-containing-protein
MKLSKHLLSKAVAIAAICATMGTTTLAAPQGTFDTSEINITGQASRSVAPNYAILTLGITSQNTNINAAKSNNDRIMSNLISQLANLGVAKKDIYTSSISINPTSDYQDGKRINTGYNVSNHVTVKINNLDNVGKVVDAAVSAGANDINNLSFQNDVSQQLSDSLTTEAIQNGRHKAEVIAAALGRTLGPVKTVSISTTETSTMDSGYYRNPVMLKAALETATPVEKGSLIVSQDANITYYLQ
>NZ_CP019721.1|WP_077708222.1|1202726_1203587_+|polysaccharide-deacetylase-family-protein
MYKYGKSCIKKLLYCMAICIAILAVSIGVMWGLSSDYKLYGVPVLNYHQINDEKHSALTLHVDQFKEQMEYLHNHGYNTITLNQLYDYLQNGSDLPEKPIVITFDDGYVDNYEHALPILKEYNMKATLFMISDAANTPGFVNTAQMHQMESAGFDIQGHTNHHKILTHMDPTELPDAILGGKTSMEGILGEPINYLAYPGGFNDMLVQYVTKQSGYKMAFTVQPGTVKPGDNLYALNRLAVFQGDTPYLSFWLRLHCAPLIKYTWALRDTLRDNGWTILASIVPLF
>NZ_CP019721.1|WP_077708224.1|1203595_1204090_+|MogA/MoaB-family-molybdenum-cofactor-biosynthesis-protein
MSYEVVARPLRVAVLTVSDTRTLETDKGGNKVQEFLEAANHIVADRKIVIDDCEAIINAMTPWCNDESIDVIISTGGTGIAMRDVTIEAVNSLYEKHIPGFGEIFRYLSYTEDIGTKAMASRAEAGVNNNTLMFSIPGSVGAVILAMSKLIIPEMGHLVREITK

Crispr_ID: NZ_CP019721_10

• CRISPR_ID: NZ_CP019721_10
• CRISPR_location: 1184253-1184360
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP019721_10

Consensus_repeat	Method
TGATATTGCAACTAATAAGGACAA	CRISPRCasFinder

spacers of NZ_CP019721_10

>10.1|1184277|60|NZ_CP019721|CRISPRCasFinder
TATTGCTGCGAACAAACAAAATATTGCTGATAACAAAGCGGCCATCACTAAAAATACTAG

CRISPR arrays and Neighbor proteins around NZ_CP019721_10

CRISPR arrays

The CRISPR arrays of NZ_CP019721_10

>merge|NZ_CP019721|10|1184253-1184360|CRISPRCasFinder
TGATATTGCAACTAATAAGGACAATATTGCTGCGAACAAACAAAATATTGCTGATAACAAAGCGGCCATCACTAAAAATACTAGTGATATTGCAACTAATAAGGATAA

>NZ_CP019721|10|9|1184253-1184360|CRISPRCasFinder
TGATATTGCAACTAATAAGGACAA	TATTGCTGCGAACAAACAAAATATTGCTGATAACAAAGCGGCCATCACTAAAAATACTAG
TGATATTGCAACTAATAAGGATAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019721.1|WP_077708211.1|1173083_1174280_+|divalent-metal-cation-transporter	unknown	unknown	gnl|CDD|224826
NZ_CP019721.1|WP_077708212.1|1174354_1175098_+|5-oxoprolinase-subunit-PxpB	unknown	unknown	gnl|CDD|367142
NZ_CP019721.1|WP_077708210.1|1169594_1170695_+|2-iminoacetate-synthase-ThiH	unknown	unknown	gnl|CDD|236425
NZ_CP019721.1|WP_021147832.1|1167287_1168592_+|phosphomethylpyrimidine-synthase-ThiC	unknown	unknown	gnl|CDD|376689
NZ_CP019721.1|WP_021147837.1|1171346_1171994_+|thiamine-phosphate-synthase	unknown	unknown	gnl|CDD|238317
NZ_CP019721.1|WP_021147838.1|1172174_1172942_+|5-oxoprolinase-subunit-PxpA	unknown	unknown	gnl|CDD|212099
NZ_CP019721.1|WP_051147513.1|1170701_1171343_+|sulfur-carrier-protein-ThiS-adenylyltransferase-ThiF	unknown	unknown	gnl|CDD|236320
NZ_CP019721.1|WP_077708214.1|1175084_1176107_+|biotin-dependent-carboxyltransferase-family-protein	unknown	unknown	gnl|CDD|224895
NZ_CP019721.1|WP_077708221.1|1194468_1195215_+|ubiquinone/menaquinone-biosynthesis-methyltransferase	unknown	unknown	gnl|CDD|234689
NZ_CP019721.1|WP_077708217.1|1185817_1187227_+|MATE-family-efflux-transporter	unknown	unknown	gnl|CDD|240542
NZ_CP019721.1|WP_077708222.1|1202726_1203587_+|polysaccharide-deacetylase-family-protein	unknown	unknown	gnl|CDD|213023
NZ_CP019721.1|WP_004692958.1|1195195_1195927_-|SIMPL-domain-containing-protein	unknown	unknown	gnl|CDD|225516
NZ_CP019721.1|WP_021147833.1|1168615_1168813_+|sulfur-carrier-protein-ThiS	unknown	unknown	gnl|CDD|340451
NZ_CP019721.1|WP_004692962.1|1190292_1190949_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP019721.1|WP_021147834.1|1168814_1169585_+|thiazole-synthase	unknown	unknown	gnl|CDD|234687
NZ_CP019721.1|WP_077708220.1|1191138_1192656_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|235774
NZ_CP019721.1|WP_004692960.1|1192901_1194122_-|serine/threonine-transporter-SstT	unknown	unknown	gnl|CDD|184190
NZ_CP019721.1|WP_077708219.1|1187779_1188817_+|OmpA-family-protein	unknown	unknown	gnl|CDD|143586
NZ_CP019721.1|WP_077708224.1|1203595_1204090_+|MogA/MoaB-family-molybdenum-cofactor-biosynthesis-protein	unknown	unknown	gnl|CDD|238451
NZ_CP019721.1|WP_004692963.1|1189043_1190165_+|AI-2E-family-transporter	unknown	unknown	gnl|CDD|223701

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP019721.1|WP_077708211.1|1173083_1174280_+|divalent-metal-cation-transporter	gnl|CDD|224826	COG1914, MntH, Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism].	4.46029e-67
NZ_CP019721.1|WP_077708212.1|1174354_1175098_+|5-oxoprolinase-subunit-PxpB	gnl|CDD|367142	pfam02682, CT_C_D, Carboxyltransferase domain, subdomain C and D. Urea carboxylase (UC) catalyzes a two-step, ATP- and biotin-dependent carboxylation reaction of urea. It is composed of biotin carboxylase (BC), carboxyltransferase (CT), and biotin carboxyl carrier protein (BCCP) domains. The CT domain of UC consists of four subdomains, named A, B, C and D. This domain covers the C and D subdomains of the CT domain. This domain covers the whole length of kipI (kinase A inhibitor) from Bacillus subtilis. It can also be found in S. cerevisiae urea amidolyase Dur1,2, which is a multifunctional biotin-dependent enzyme with domains for urea carboxylase and allophanate (urea carboxylate) hydrolase activity.	9.06673e-94
NZ_CP019721.1|WP_077708210.1|1169594_1170695_+|2-iminoacetate-synthase-ThiH	gnl|CDD|236425	PRK09240, thiH, 2-iminoacetate synthase ThiH.	0
NZ_CP019721.1|WP_021147832.1|1167287_1168592_+|phosphomethylpyrimidine-synthase-ThiC	gnl|CDD|376689	pfam01964, ThiC_Rad_SAM, Radical SAM ThiC family. ThiC is found within the thiamine biosynthesis operon. ThiC is involved in pyrimidine biosynthesis. ThiC participates in the formation of 4-Amino-5-hydroxymethyl-2-methylpyrimidine from AIR, an intermediate in the de novo pyrimidine biosynthesis. Thic is a member of the radical SAM superfamily.	0
NZ_CP019721.1|WP_021147837.1|1171346_1171994_+|thiamine-phosphate-synthase	gnl|CDD|238317	cd00564, TMP_TenI, Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5- (beta-hydroxyethyl) thiazole phosphate to yield thiamine phosphate. TenI is a enzymatically inactive regulatory protein involved in the regulation of several extracellular enzymes. This superfamily also contains other enzymatically inactive proteins with unknown functions.	6.14154e-70
NZ_CP019721.1|WP_021147838.1|1172174_1172942_+|5-oxoprolinase-subunit-PxpA	gnl|CDD|212099	cd10787, LamB_YcsF_like, LamB/YcsF family of lactam utilization protein. The LamB/YbgL family includes the Aspergillus nidulans protein LamB, and its homologs from all three kingdoms of life. The lamb gene locates at the lam locus of Aspergillus nidulans, consisting of two divergently transcribed genes, lamA and lamB, needed for the utilization of lactams such as 2-pyrrolidinone. Both genes are under the control of the positive regulatory gene amdR and are subject to carbon and nitrogen metabolite repression. Although the exact molecular function of LamB is unknown, it might be required for conversion of exogenous 2-pyrrolidinone to endogenous GABA.	8.22068e-140
NZ_CP019721.1|WP_051147513.1|1170701_1171343_+|sulfur-carrier-protein-ThiS-adenylyltransferase-ThiF	gnl|CDD|236320	PRK08644, PRK08644, sulfur carrier protein ThiS adenylyltransferase ThiF.	3.10499e-84
NZ_CP019721.1|WP_077708214.1|1175084_1176107_+|biotin-dependent-carboxyltransferase-family-protein	gnl|CDD|224895	COG1984, DUR1, Allophanate hydrolase subunit 2 [Amino acid transport and metabolism].	1.40475e-110
NZ_CP019721.1|WP_077708221.1|1194468_1195215_+|ubiquinone/menaquinone-biosynthesis-methyltransferase	gnl|CDD|234689	PRK00216, ubiE, bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE.	1.44245e-98
NZ_CP019721.1|WP_077708217.1|1185817_1187227_+|MATE-family-efflux-transporter	gnl|CDD|240542	cd13137, MATE_NorM_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	1.47114e-86
NZ_CP019721.1|WP_077708222.1|1202726_1203587_+|polysaccharide-deacetylase-family-protein	gnl|CDD|213023	cd10918, CE4_NodB_like_5s_6s, Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands. This family belongs to the large and functionally diverse carbohydrate esterase 4 (CE4) superfamily, whose members show strong sequence similarity with some variability due to their distinct carbohydrate substrates. It includes bacterial poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, hemin storage system HmsF protein in gram-negative species, intercellular adhesion proteins IcaB, and many uncharacterized prokaryotic polysaccharide deacetylases. It also includes a putative polysaccharide deacetylase YxkH encoded by the Bacillus subtilis yxkH gene, which is one of six polysaccharide deacetylase gene homologs present in the Bacillus subtilis genome. Sequence comparison shows all family members contain a conserved domain similar to the catalytic NodB homology domain of rhizobial NodB-like proteins, which consists of a deformed (beta/alpha)8 barrel fold with 6 or 7 strands. However, in this family, most proteins have 5 strands and some have 6 strands. Moreover, long insertions are found in many family members, whose function remains unknown.	1.62856e-53
NZ_CP019721.1|WP_004692958.1|1195195_1195927_-|SIMPL-domain-containing-protein	gnl|CDD|225516	COG2968, COG2968, Uncharacterized conserved protein [Function unknown].	6.4365e-42
NZ_CP019721.1|WP_021147833.1|1168615_1168813_+|sulfur-carrier-protein-ThiS	gnl|CDD|340451	cd00565, Ubl_ThiS, ubiquitin-like (Ubl) domain found in sulfur carrier protein ThiS. ThiS, also termed Thiamine biosynthesis protein (ThiaminS), is a sulfur carrier protein involved in thiamin biosynthesis in prokaryotes. It has the beta-grasp ubiquitin-like (Ubl) fold with low sequence similarity to ubiquitin (Ub), and is activated in an ATP-dependent manner by sulfurtransferases, similar to the activation mechanism of Ub-activating enzyme E1. ThiS has common evolutionary origin with Ub-related protein modifiers in eukaryotes, a beta-grasp fold as Ub, and is closely related to proteins MoaD and Urm1.	8.89718e-17
NZ_CP019721.1|WP_021147834.1|1168814_1169585_+|thiazole-synthase	gnl|CDD|234687	PRK00208, thiG, thiazole synthase; Reviewed.	2.83468e-144
NZ_CP019721.1|WP_077708220.1|1191138_1192656_-|FAD-dependent-oxidoreductase	gnl|CDD|235774	PRK06292, PRK06292, dihydrolipoamide dehydrogenase; Validated.	7.16502e-130
NZ_CP019721.1|WP_004692960.1|1192901_1194122_-|serine/threonine-transporter-SstT	gnl|CDD|184190	PRK13628, PRK13628, serine/threonine transporter SstT; Provisional.	0
NZ_CP019721.1|WP_077708219.1|1187779_1188817_+|OmpA-family-protein	gnl|CDD|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	4.97394e-29
NZ_CP019721.1|WP_077708224.1|1203595_1204090_+|MogA/MoaB-family-molybdenum-cofactor-biosynthesis-protein	gnl|CDD|238451	cd00886, MogA_MoaB, MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea, and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MogA, together with MoeA, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes. In contrast, MoaB shows high similarity to MogA, but little is known about its physiological role. All well studied members of this family form highly stable trimers.	1.61805e-59
NZ_CP019721.1|WP_004692963.1|1189043_1190165_+|AI-2E-family-transporter	gnl|CDD|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	6.96798e-40

Protein sequences

>NZ_CP019721.1|WP_077708214.1|1175084_1176107_+|biotin-dependent-carboxyltransferase-family-protein
MDINEFQRALIRVDAPGMYTTIQDIGRIGFQQYGMPVAGPMDSESYLLGQALVGNKEPLGALECTVLPPTLTVQGTCIVAFTGADMHPTINNVVVPRYIPFICHEGDIISGGFSQCGVRMYIAFSGGVDVPAINGSVSTHTKAKIGGFEGRSLQAGDQFGIKAFTRHEVNVCDFYGTHKLFNTALYNRGGRECHEPLRVVLGEQAKYFTEKGIKTFGSKIYTLTVQCDRMGFRLDGPVIEHIDSADIISDGAVFGSIQVPSDGNPIVLMADRQTTGGYTKIGTVITADLPRLSQLPVGDGIHFDIISVEEAQEIYRTYIRHLHKRIELAHEQSLYVFKVS
>NZ_CP019721.1|WP_077708212.1|1174354_1175098_+|5-oxoprolinase-subunit-PxpB
MKPTISPVGDCAISIDFGQVIDPKINRHIRQIIEQIKDLQLDGIIELVPTYCALLVQYDAMVYSYSDICRILEPTLQESVTDSANELVTIVEIPTVYGGEFGPDLGFVASYNHLSEAEVVSIHSGTDYLVYMLGFIPGFTYLGGMDPRIATPRLSSPRTLIPAGSVGIAGEQTGTYPSDSPGGWQIIGRTPVTMYDMSKEQAALLQAGDYVRYVSIDENEFHRVKSLGMEYIPSIYEIESGDLRGYK
>NZ_CP019721.1|WP_077708211.1|1173083_1174280_+|divalent-metal-cation-transporter
MKPITGKASFSVLLGAAFLMATSSIGPGFMLQTAAFTNELKADFAFAIVVSVIFSIIAQLNVWTIIGVSQMRGQDIANKVLPGLGYIVAFLISLGGLAFNIGNIGGASMGLNIIFGIDTTTAAAISGILGILLFTSKKMGGVLDNTAKVLGTVMLVLIAYVAFSTNPPVGEALSHSVIPEHVPWLATITLIGGTVGGYITFSGGHRLIDAGITGQEHLKDVRRAAIMGMSVDALVRVLLFLAVLGVVSMDFVLDSKDPAGSAFLLGAGEIGHKLFGIVFFCAALTSVVGAAYTSVSFLKTLFKIVERNEKLTIMAFIFISTCILIFIGKPVSLLILAGSVNGLILPVTLAVMLVATHKSEIVGTYKHNKLLYYTGWIVVLVTSYIGVTSLKGIAKLLG
>NZ_CP019721.1|WP_021147838.1|1172174_1172942_+|5-oxoprolinase-subunit-PxpA
MSHYVDLNSDLGESFGNYTLGMDSEVLNHVTSANIACGWHAGDPLIMDATVRICKEKGVAIGAHPGYPDLMGFGRRAMAVNPAEAKAYMMYQLGALQAFCDSYDITLQHMKLHGAFYNTACVTPVLADAILDGLQAVNPNIAAMVLSGSYIAQEAQRRGIPVIQEVFADRGYTEEGTLVPRTEVGAFIKDPQEALDRVLMMVTKGKVVTNTGKTIDIVADSVCVHGDNPEAIAFTRYIREGLIKAGVTVANFQHR
>NZ_CP019721.1|WP_021147837.1|1171346_1171994_+|thiamine-phosphate-synthase
MNRKDKLTEVINACPIYGITGGTRDVVTLVKDMLSAGIRIIQYREKGKTPILRYQEAMILRRLTYDYHALLIIDDYVDLALAIHADGVHIGQDDLPPNTVRRIVGPNMLIGWSTHSISDLKAANRYTSVIDYIGVGPIFSTQTKPNANPVGISYVYWAKQFSKVPIVAIGGIKTTNADIVWQAHPDFICAVSEITESDNIQNTVYELMTGYSRVR
>NZ_CP019721.1|WP_051147513.1|1170701_1171343_+|sulfur-carrier-protein-ThiS-adenylyltransferase-ThiF
MCMAHMNNEFETAISHFYSPEEFRKLQNSVVGIIGAGGLGSNCAVNLVRSGIRNLIVADYDIVELSNLNRQHYFSCHVGQYKVEALQDVLTALNSNVIVKIYKDKLTTENIPEIYKKADILIEAFDAVEAKSMFLEAATSVDVPKIMVSGLAGIGNSDALRTKKLGQNLYIVGDEHSGVDNAYPYAPRVAIAAAKQADLALSLLLEKTMSNEV
>NZ_CP019721.1|WP_077708210.1|1169594_1170695_+|2-iminoacetate-synthase-ThiH
MSFLDVLSRVSDEDIAETLEAITGDEILSTLSKPALAIDDALILLSPQALLYLEDMAQLAHEQTVQQFGYTIQLFTPMYISNYCDNGCVYCGYSHHSGIAREKLSLNDIELEAKAIAETGLEQVLVLTGESKSCSPPAYIQAAVETLVPIFSSVSIEVYSLTLEEYKGLVAVGADGMTMFQETYNPTLYAQLHPFGPKSGFAKRIDTPELACQAGFRVVNIGALMGLDEWRREAYKTMLHLNYLVQHYPDVELSVSVPRIRPCAVGYSPKYPVDDTALVQYILALRLLFPRVGITLSSRESKYMRDNLVRLGITKLSAGVTTSVGGHTKQDDSSQFTISDNRSVSEMAVMLENNGYQPIYKDWQTL
>NZ_CP019721.1|WP_021147834.1|1168814_1169585_+|thiazole-synthase
MLDSFTVGNTTFSSRLLVGTGKYASYNLMRDALVASKSDIVTVALRRAGTTQSEEDILNYIPDRMHLLPNTSGARNADEAIRIARMARELGCGDLIKIEVIQDQMYLMPDNLETIRAAEVLAKEGFIVFPYMSPNLMDAKRLVDAGASCIMPLASPIGSNRGLEAKGLIEILINSIDVPIIVDAGIGRPSDATIAMEMGASAVLVNTAIATSSNPVGMAEAFYYAVEAGRKAYLAKCAPKKSVGSASSPLTGFLRK
>NZ_CP019721.1|WP_021147833.1|1168615_1168813_+|sulfur-carrier-protein-ThiS
MDLIVNGEPKYVVGEQLHLILDELGYSGKHFVVELNGEILSKEAYTTTKLTAADRLEIVSFVGGG
>NZ_CP019721.1|WP_021147832.1|1167287_1168592_+|phosphomethylpyrimidine-synthase-ThiC
MFMTQLESAVAGVVTKEMKVVAEKERMDEEVLRSLVAAGKVVIPCNKQHTSISPEGIGKRLRTKVNVNLGTSKDVTDYDSEIEKVNRAIRLGAESIMDLSTHGDTRIFRRKLIETSPVMIGTVPIYDSVIHHQKDLGELTAQDFLDTIRLHAQDGVDFITIHSGITRKTIDQIKNHKRLLNIVSRGGSLVFAWMSMTGHENPFYEYFDEILKICKEYDVTLSLGDACRPGCLADATDVCQIEELVRLGELAKRAKQYGVQAMIEGPGHVPLHQIQMNMEIQESLCDGAPFYVLGPLVTDIAPGYDHITAAIGGAVAGMYGASFLCYVTPAEHLALPNADDVKDGIMAFKIAAHAADIARGIPNARDIDDTMAKARQVLDWEAQYACALDPERARSIRESRAPEEDHGETCSMCGKFCAVRSMNKALQEEYIDIL
>NZ_CP019721.1|WP_077708217.1|1185817_1187227_+|MATE-family-efflux-transporter
MLDRIQRWLSVDTMLPVAERLGPVGTTKQLYGNYLKIAWPATLQGLMLQFMTAIDLAMVGALGASALASVGIMGQPEMVMLIFCRALSIAVTAIIARRHGEGGVDGMNAVLKQSILLNFLIYVPLLLICFLNLEHILRFTGAEDGYIETAVWYGRFIVISLIFQSFSQIVGAALIGYGNTKVIFKSNVVGNILNTIMNFFLIYGIGFFPELGVMGAGVSTMISSAIIALLLLRTISQHTSTGLTLRHPSKWTFERPVLHTMFHVGGSSLGEQFFERFGMYTYTMIVASLGAVPLAAHYVCMNLMDIFYYFAMGLGFAGASHTGQSLGHKRPDIARTYGKIGARIGLVVGLVSALIFMGPGDFLVQLYTRESDVVTLSATLMGIMAIAAFPQALQQVYSGVLKGAGDTYYIMKYSLVSVAIIRPIITYLLCITLGLGLFGAWLSLCFDQSLRLCCSYLRFIRGTWQHKVV
>NZ_CP019721.1|WP_077708219.1|1187779_1188817_+|OmpA-family-protein
MNKKLLALLAVAAVGVSVAGATPQTQFNKGEFQVNLGASDSKAKTKAWTSDAKWNFDGGVTYAFTDKTALQYQYHGLNDKMFGTSYSDRMQEVNLIQSLNKNFAVYGGYAHISGDTFPKANNIAQLGVIGKANLGSKVDVYGKAGVGTKRTTTWEAGLGYKVNQDWDINAGYRYINTKRDDKSNISFQGPVVGLSYRFGGHKSVAPVYTPAPAPVYTPAPAPTVEAPAYKTPKLDYYVQSIYFDSDQDVARADQYPNLTAAVNAANQYSQDQVKLMGNADTDANPQYNIALSERRVQHVAQYLVNHGVSADRLIGIANGDVKPVATNSTAAGKAENRRVDVYIHR
>NZ_CP019721.1|WP_004692963.1|1189043_1190165_+|AI-2E-family-transporter
MKEFKYYKQLIGAIILAGIMIMMALRISDIASGLDAIFTAFVPLIVGACIAFVLDILVVRYERWLWPKCGSGWKYKIRRPLSLLLSFVTISVIVYFIARMALPQLIHSMSIIVAASPQLYTDFQTWMQHITETVPMASNQTIIDALSGENIAKYTREWGTKGGTYIVNAMGTVLSWTLNIGLGLIFAVYMLLDKERLMLQGKRILKAYASDEWVNRVSYVTRVAVQTFSNFFVGQFIDALVLGVMVGITLWLFNIEYATTIACVIGLTGLIPLLGIYVGGIIGAVMLLTVSPMDALIYVIILEVLHQIESNFIYPKIVGNSVGLPGLWVFAAVIVGGSLMGVTGMLIGVPLVATCYKLIMTDVDGRLASNEGL
>NZ_CP019721.1|WP_004692962.1|1190292_1190949_+|hypothetical-protein
MNKKLISMALTGVLAVGMLSVATPSVADARKTKPETSTDISVKRAPGESIVMTMSQIGTIFQNRYPNAALHSVELNSNDLNYGYKVVGYSKYHQYKMKIDVITGNASDMEEGGKPKKVIGEIFNKDKVIESTQAERVAKQQLGNDAVMKGWKIEAHNGKVLYYVTMHQDGKKVVVTVDAETGAYVEQSKSYKLPPEPDQGFDGRKTNLVWGSDIDMGR
>NZ_CP019721.1|WP_077708220.1|1191138_1192656_-|FAD-dependent-oxidoreductase
MKQYDIIVVGTGGATIVADAALKKGLKVAIIEKGKFGGTCLTRGCIPTKVMVTAANAIQETKEFKKIGVNVGPATMDWHTVSKRTWHKIDESAGIYDYYNAYDNVDVYRGAASFVSDKVMNIHLNDGSGIVEITAPTIILGTGGYSNVPNVPGLQESGFLTSESLFGDKFPKQPYKSLAVLGAGPIGVEFAHVFDSAGTKVTILQHNVRLVPKEDADISEHLLNNYRERGINVLLNQDTVEIRQEDGLKVVVTKDRTTGEITETKVEEILVAAGIRPAVEELHLENTGIETRPKGWIKTNEFLETSVDGIYALGDVNGEPAFRHRANYEADIIAHNLFYATSEDDYRWARYDTLPKVTFSYPEIGSVGLTEAEAIKAGYNVGVGKNFYSSTAKGYAMGINPGDVNDGFVKIVVDKDTNHILGMHVVGPQASILFQPYVNLMNSGVTPLTAINEEIASERTKRLREKGITREMDPRSVITVGETMSPHPSLVEVIMWTQVYYENRW
>NZ_CP019721.1|WP_004692960.1|1192901_1194122_-|serine/threonine-transporter-SstT
MNRFVKSINRVSLIQQIIIGLIIGILTALYVPDVANELALLGVLFVGALKGIAPILVFFLVIAAISKHRSGQKTGMGSVITLYLLGTFLSAALAVIVSFFFPTTLHLAAGAADAAPPQGIVEVMTTLLKNVVDNPVKALMTANYIGILGWALIIGGALRHAPMNTKEVMESIAQAITTVVGWIIRFAPLGIMGLVAESIATNGIEALIGYFQLLVLLLGSMIFVALVINPILSFIYLRRNPYPLVFKCLRESAIYAFFTRSSAANIPVNLDLAKRLKLNPDMYSVSIPLGATINMGGAAITITIMTLAAAHTLGIVVDIPTAILLSVIATIGACGASGVAGGSLLLIPLACSLFGISNDVAMQVVGVGFIIGVLQDSTETALNSSTDILFTATADYAKRGYHQDWN
>NZ_CP019721.1|WP_077708221.1|1194468_1195215_+|ubiquinone/menaquinone-biosynthesis-methyltransferase
MNTKEFKTYADKEKFVQGVFSNIAKNYDLMNTVLSFGQDYFWRKFSVKAMNIGPHQYVLDVACGTCVFTKEALCQEPTLKVEALDFNSEMLNQGRVRIEAAGLLNQVNLVQGDAMALPYEDNTFDAAMSGFAMRNVPDIKQVLSEMQRVVKPGGKVVVLELAKPSMFGFKQLYNFYFSYILPIIGKLSKDNSSYAWLPESLRRYPHQSEILEIWKSLGYENATYHELTGGIVAVHEGVVPENSIVDNK
>NZ_CP019721.1|WP_004692958.1|1195195_1195927_-|SIMPL-domain-containing-protein
MKLSKHLLSKAVAIAAICATMGTTTLAAPQGTFDTSEINITGQASRSVAPNYAILTLGITSQNTNINAAKSNNDRIMSNLISQLANLGVAKKDIYTSSISINPTSDYQDGKRINTGYNVSNHVTVKINNLDNVGKVVDAAVSAGANDINNLSFQNDVSQQLSDSLTTEAIQNGRHKAEVIAAALGRTLGPVKTVSISTTETSTMDSGYYRNPVMLKAALETATPVEKGSLIVSQDANITYYLQ
>NZ_CP019721.1|WP_077708222.1|1202726_1203587_+|polysaccharide-deacetylase-family-protein
MYKYGKSCIKKLLYCMAICIAILAVSIGVMWGLSSDYKLYGVPVLNYHQINDEKHSALTLHVDQFKEQMEYLHNHGYNTITLNQLYDYLQNGSDLPEKPIVITFDDGYVDNYEHALPILKEYNMKATLFMISDAANTPGFVNTAQMHQMESAGFDIQGHTNHHKILTHMDPTELPDAILGGKTSMEGILGEPINYLAYPGGFNDMLVQYVTKQSGYKMAFTVQPGTVKPGDNLYALNRLAVFQGDTPYLSFWLRLHCAPLIKYTWALRDTLRDNGWTILASIVPLF
>NZ_CP019721.1|WP_077708224.1|1203595_1204090_+|MogA/MoaB-family-molybdenum-cofactor-biosynthesis-protein
MSYEVVARPLRVAVLTVSDTRTLETDKGGNKVQEFLEAANHIVADRKIVIDDCEAIINAMTPWCNDESIDVIISTGGTGIAMRDVTIEAVNSLYEKHIPGFGEIFRYLSYTEDIGTKAMASRAEAGVNNNTLMFSIPGSVGAVILAMSKLIIPEMGHLVREITK

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP019721_3	3.4|531672|41|NZ_CP019721|CRT	531672-531712	41	NZ_CP019721.1	1072160-1072200	0	1.0
NZ_CP019721_7	7.5|562923|41|NZ_CP019721|CRT,CRISPRCasFinder,PILER-CR	562923-562963	41	NZ_CP019721.1	320339-320379	2	0.951
NZ_CP019721_6	6.5|553066|87|NZ_CP019721|CRISPRCasFinder	553066-553152	87	NZ_CP019721.1	552651-552737	27	0.69

1. spacer 3.4|531672|41|NZ_CP019721|CRT matches to position: 1072160-1072200, mismatch: 0, identity: 1.0

taatcaagcacgtaattacgtaccaaacctaacgtaattat	CRISPR spacer
taatcaagcacgtaattacgtaccaaacctaacgtaattat	Protospacer
*****************************************

2. spacer 7.5|562923|41|NZ_CP019721|CRT,CRISPRCasFinder,PILER-CR matches to position: 320339-320379, mismatch: 2, identity: 0.951

aaaaaactaattgatgcgtggagctggctcaactccgataa	CRISPR spacer
aaaaaactaattgatgcgtggagttggctcaactccgacaa	Protospacer
***********************.**************.**

3. spacer 6.5|553066|87|NZ_CP019721|CRISPRCasFinder matches to position: 552651-552737, mismatch: 27, identity: 0.69

tcaccttcgttttaccttcacttcgttcaggtacttgagatgtgcggacctcatcgtcgc	CRISPR spacer
tcaccttcgttttaccttcacttcgttcaggtacttgagatgtgcggacctcatcgtcgc	Protospacer
************************************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP019721_5	5.13|550951|36|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR	550951-550986	36	NZ_CP020607	Lactococcus lactis subsp. lactis bv. diacetylactis strain FM03 plasmid pLd3, complete sequence	2112-2147	8	0.778
NZ_CP019721_5	5.17|551239|36|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR	551239-551274	36	MN694456	Marine virus AFVG_250M1118, complete genome	49079-49114	10	0.722
NZ_CP019721_5	5.17|551239|36|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR	551239-551274	36	AP013539	Uncultured phage_MedDCM-OCT-S28-C3 DNA, complete genome, group G7, isolate: uvMED-CGR-U-MedDCM-OCT-S28-C3	13121-13156	15	0.583

1. spacer 5.13|550951|36|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020607 (Lactococcus lactis subsp. lactis bv. diacetylactis strain FM03 plasmid pLd3, complete sequence) position: , mismatch: 8, identity: 0.778

atgaacaaaaagatcgaaaagatgactttagatttt	CRISPR spacer
atgaacaaaaatatcgaaaatatgaccctaaaaatg	Protospacer
*********** ******** *****..**.*  * 

2. spacer 5.17|551239|36|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR matches to MN694456 (Marine virus AFVG_250M1118, complete genome) position: , mismatch: 10, identity: 0.722

cctcatttaattaattaaaattattttattttggca	CRISPR spacer
atttatttaattaattaaaatagttttattaattaa	Protospacer
 .*.***************** .*******     *

3. spacer 5.17|551239|36|NZ_CP019721|CRISPRCasFinder,CRT,PILER-CR matches to AP013539 (Uncultured phage_MedDCM-OCT-S28-C3 DNA, complete genome, group G7, isolate: uvMED-CGR-U-MedDCM-OCT-S28-C3) position: , mismatch: 15, identity: 0.583

cctcatttaattaattaaaattattttattttggca-------	CRISPR spacer
-------aaatttaataaaattattttaattaatgaaattaat	Protospacer
        **** * ************* ** .  *       

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	323512 : 342708	18	Synechococcus_phage(23.08%)	terminase,head,portal	NA
DBSCAN-SWA_2	1045906 : 1051895	6	Prochlorococcus_phage(33.33%)	NA	NA
DBSCAN-SWA_3	1063084 : 1139493	102	Bacteriophage(25.0%)	terminase,tRNA,plate,tail,capsid,protease,integrase,portal	attL 1063069:1063087|attR 1101978:1101996
DBSCAN-SWA_4	1802518 : 1810782	8	uncultured_virus(33.33%)	tRNA	NA
DBSCAN-SWA_5	1974848 : 1985379	10	uncultured_phage(42.86%)	NA	NA
DBSCAN-SWA_6	2043625 : 2053096	7	Klosneuvirus(16.67%)	tRNA,protease	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP019721|323512:342708|DBSCAN-SWA
ATTATTTACCAGGGTTTTTGTACAAGCCACGGAAGTCGAGCGCTGTTGCGTTGCAATCCATTGCTACTTTGTACTCAATGCCGTCAACTTTAAAGCCTGTTTGTGTTTCCAATCGAGGTGTTTCAACACCGTTCAAGTACGTTACTTCGATAGTTTGAACATCTGTAGGACGAGCTGCTAAATACCATGCGTGTGGATCTGTTAATGCCGCATCAACTACAATAGTGAATCGACCGCCGAATGGGTTAACTGTACCATTGCTACGAGCTGGGTCCACTGTGGATTTAACCAATTCGTAAGCCAATGCTTCGAGTTCTGGCGGAATAATCAAATATGTAGGTGCGATGTTCAAATTGCGATTTTCGCCAATATGCTTTTGACGGCGCATTGCTGCTACACCCGCAGATAAGGAGGCAACACTTAATTCAGCACCAGTAGCCGCCAAGTTGCCTCTGTCAGTACCGAATAGTGCTTTACCGTCACTCAATACGGTATTACCTGTTAGCAATCCGTACACCATGCTGTTGATGGTATCCTTTGCAGAACGACCAAATTTGGAAGCGATATCTTTGAACACACCCAAATCATCATTGATGATAGCTTGTCGTGTTAAGCTGAATGTACGACCGTATGTTAATACACGAACGTCGTTACCAGCTTCTTCCAACTTAGAATCCTTGAATTGTCCACCTTCAGGAACGAGTTTCAATTCAGCTGTTTCAGAAAGTAAAATACGTTTTGCCGGTTTGAAATCACGATTACTACCTTTGCCGGTCCATGCATCGAATGTAGTCGGTGCAGTTTCATAGCCTTGTACCAAGGACTTATTTGCTACGTTAGACAAAGCAATTGGGAAGGTAGACGTGGAGTTGATAGCTTCACGAGCCAATTCCAAACGGTCAGCATAGTTAGCGGTTAATCCTTCACGAACTAAAGACTCACGAGCTAATTCCATCAAGGACATAGAACGAAGTTCATTTGCGCCTGGTGCAGGGTTCGCAACAGGGATGCCTGCAGACATCATCAAAGCATCTTGCATAGCCATACGGAACTTATCAGAATCTGCTTCACCAACTTTAACGGATACTGGTTTATTGCGTTCACGCAACGCATCCATTACTGCCTCACGAACTTCGGCAACAGATTTGCCGGATTTGATGAATTCATCTACACCGTCAACTTCGAAATCACGGCATAGGCTAGTGATTGTGGATACACGTTCACGTTCTGCTGCAATCAATTTTTTAGCGTCATCCGCATTAAAACCTTTAACTCCGGACTCTGGTACTTCCGGTACTACTTGTGGCACGTTTTGCTCAGTGCCTTTTGCTTTTGCATCACCTTTCATAGGTTCCTCCTCATTATCATCTACACTTCTGCCTACCCCTACACTTGGATCTGCAGGGACGGACACAATACTAATTTCCAATGGTTCCCAGCCTGTAATTACATATCCTGGGCCGGTAAAACGACCATTGGAGCTTTTAGAATCGAAATCGATTAATTCCTCATATCGACTTATGTCATATCCGACACTCACACCTTGTAACGTGCCTTTTAACACTTTTTGATAAATCTTTTCAGATTCATCATCTTCATCGAATCGAACAATCGCCTTGCCGCGATTATCTTCAATCCACACTTTATCGATGTGACCAACAACTGCACTGCGATTGTGATTGAATAGTAATGTTCCTAAACCGTTATTAAATCGGTCTAGGTTAACGCATCCTTCGTCATGACACAATATCTCTGTTCCGAACCATCTTTCATATGGTTCTTCAGAGGAAAAGGACAATTCGACGGTACGGTCATCATTCGCCTCGATGTTTGTAATTTGCGCCTCTCGGGCATATTTACCTAAGAGCTGATTCTTTGCAAATTTCCCCACTAGCTATCATCTCCTTTCATATCAGTGGCGTTATCATCCGCTAGATTCGTTATGTCCCCATTCATATCAAGGGCAACACCCAATTCCTTAATGCGGTCTTGTTCCAGCTTCCGCTGTTCTAATACTTCTTCCCAGTCCTTACCTGATGCACTACATACATCCTCGAGCGTTGTGAGTCCTGCCTTAATCGCTTCCTTGTTAGCATTAACTTCCTTAACAGGGTCAATCCAAGACCAGCCTGGAGCTAACCACGCTACTTTTTTATAAAGTTTTGGGTTCGCTGCATAGTCATTGGCCGGGATAATTCCCTTCAGGTAGCACGCTTCAATGAAAGCCCGCCATACCGGCATACAAAAATGCTCAATTATAAAACGCTGCATCTGCTTGAATGATTGCTGGTCCTCCAGCATATTCTGCCGAGCTGCGGAGAAGTTACCACTAATATTGCGCGTCACTATGTCCGCGCTTAGACCCATACCTGACGCTATGCGTCTTGTTTGTGTCGCTGAGTATTCTGATGCGGTTCCTGCATTTCGCTTAGGCTCCGCAAACGAAATAGATTCACCGGCACGTAGATGCTGGATAATCCCTGGTGCCATCGAGCGGACTTTTTTGCCTTTACTGTCAATCTTACTTGCAACCATCGGGTTACCCCCAGTATTACTTGTTACGAACGCGCCGAAACATGCGGCTACACGAGCCGCTATAAGGTCGGCATCCATGTATTCATCTACGTCGTGAATACGCTTTAATACGAGGGCTAACATACTAACCCCGCGCAGTTCACTAGGTCTACGAGGCTTATGTAACAGGAAAGCCCTATTACTTGGTAATCGTGCCTCATTAAATGACCGTATTCCTAACGGGTCTGTTTGGAATACGTGATATGCTATTGGTCTTCCGTATTTATTAACTTCCACGCCATTAACAATACTGTTGCCATTCTCGCTTACCGATACGGCTCCGATATTCTCGCCCTCGATAAGCTGTAATGATAGTGGTATATCTGCGCCTTCGGAGGTCATATTAACTAAGATTTCCCCGTCATAGACCATTCGGCGCAGAGCCATTTCCTGCAATTCGTAGAACGTAGATATCCCTCTGATATCCGCATTCTCTTTATCCACCCAGTCAGACCAAGCCTCCTCAATCTTCTTATTGAGTCTTTCATTCAGCTTTCCTGCGCGGGTCTTAATTTTGCACTGTGGCTTTATTCCGGTACCTACTACATTCCGTAGTAATGCCAATACAACACTTTCAGCGAGGTCACTATTAAGTTCTGCTGCACGTGCACGACCGCGGATCAAATCACGTTGGCCTGATGCTACCTGTTCAGCTGTACCAAATACTGGCATCCAGTCGCCACTCAATCGGTCTGTTGACGCCGCATCATATCCACGTTCAAGCGAACTACGGAAATATGCCCTGCGAGCAGCACGCTCTGGATTGAAATAAGCTATTACCTTATCAAGTATGTTCATCGTCGTTCCCATGACACGTAGGATGTCGTGCTATTACATTCCTCATCATCAACGCGAACCATTAACTCACGTTCACGGGCATATAATGTCGGTAGGTCATGCGTTTTAAAACGCTTACCACCTACAGACATCTCGGCGTATCCATTCGTCTCGATTTCCTCGATTATCGTTCGAATACGCTCCAAGTCTTCTCTTGCGCTCATGGTCTCACCTCCTTCTTAGCTAAACCAACCTCGGCTATCTGCATTAAAGTCTTCAACATCCGTATCTTCGTCCTCCTCATCGGTATCCAGATTATATTCGGGTAAGTATTTAACACCTACCGAGTCCGCCACCATGGCGTTGTATACACACGTATCCAACAAGTGATTTGTTGGATGACTGGTTAATGGTTTCCATTGCACTGTAACTGCTCCGGTCTTTACATTTCGGATTTCTTGCTTTTCCTCCGACCGGAGGTGTTCCGAATATTCCTCCGGGCAATCCTTAAATAAATGGATTGTGCCAGGCTCATTAGCCGGACGTACCATACGTGCAAATATAAAGTCCTTCCAGTAATCGGTATTCACTACGTACAGCTTCATGCCTCCGATGACGCCCTTCTCGATGCTGCTCATCTTATAAGGCGGCGCTAGAGGACTGTGCGATGAATCACCTTTAACTGGCACGCATACTTCTGGGTACTGCGCACAGTACTGATATACTTCATCTGTTCGGTAGCCACTATCGATACCGGCCCTCACAATCTTACGGGCCTCACCATACTCTGATGGATATTCTCTATCGATGAGTATCTCGGTTAAGTCTGCCCAACTACTTGCTTGACCATAATCGACTAAGTAGCTTGATACACCATGGGCGTAGGCTCTAACCTCCCACCAGAAATGATCCTGCTGCACGTCGACAGAGGCGATAAGTAGTGGCGCATGCTGTGGCACAACACCTCGAGGAACTTCCGATTGCGTAAACACGAGGTTCTGCGTGCTTTTAGTTTTCGCAGATTTCCACGGCTCTGCTAGCCATGAATTGATGAAGTTCATTAACTCACTTGGCGTATCTTTTGATTTGACAAACTCATACGCTACATCCCCGAAGGTGACCCATGGAGAATATAGAGATGATAGCTGATAGGCGACCGACCGGACGACTCGAACTTGCGATTCATTCACCGCCAGCCATTCACCTTGCCGGAGCATATCCATCTTATGCTTATCATCAATACGGTGCTTACAATGTTCGCACTCATAATATGCGGTATCACGTATCATATCCGCATTGCCATGGTGTTCTTCCGGCCATTTTATCTGTTTGAATTTGAGGGTCTGCGACACCCCGCAATGCGGACATGGCACGTAATACTGCTTACGTTCATTTGCGCCCATATAGGATTGCCAAATATTGCCACTTTCAATCGTAGGAGTTGACACCCTTACAATCTTCTTATCAACGAATGTCTTGGTACGTTCCTCAGCCAGCTTAATCGGATTCGCTTCCTTACCGGAGAAAGCTGGGTACTTATCAATTTCATCGAAGAATAAGTACTTAATTGACCGACTTGACAAGCTACTTGGTGAGTTCGCTCCTACGAGCACCATGTAATTCCCGTTAACGAAGTCTAACTCTAGTAGCTTACTGCTTTCGTCATACATATCCGCAAGCGGCTCTACGCTCCTAATCATTGGCTGTACACGTTTATCACTAGCGAATTTCGCGATAGTATCCGTCGGATAAACCATCATGGTTGGAGATACGGTTTGATGTAACGCATATCCAATCATATTAAGCTCAGTTTCCGTCTTACCAATCTGCGCTCCGAAACATAACGAGATGCTTTCAATGAGAGGGTCTGTGAATTTGTCCATAGGCTCCTTGAGATAAGGTGTCCGCGCTGTACGCCATCGTCCAGGTTCAGCAGATATATTAGTCAGTACCCTGTACCTATCCGCCCATTCCGAAACGGTGTATCTTTCAGGTGGCTTGAATGCCTCTAATTCCTCAGGGAACCAGTCAACCTTTGGACTTACCTTTTCCCGTGGCTTTGACTTTCGGCGTGTACTCGCCTGCGCGTGCGTAGCTTTCGAGGTATTCTTCGACAAGGCCATTCACCACCTTTTCTACACGAGCACGTTCCTCAGGATCCGTGAATTCACTTCCGATACGCTTACCTAATTTGGTAAACGATGTTTTTAATTCCAATATTCGGTTAGCCCATGCCTGCGCCACATCGGCACGAGGGACATATTCGCCATTAAGCACATCTAGCATTTTCTTTTCACGCGCGGCCTTTGCTTCTTTATAATCTGCTTCGGCTTCTAACTTACGAGTTGATGCGGATTTGCTTTTAGCGTTATCACCTTTCGCCTGTCCTAAATACACGAGGACTTCCCGGAGATTCCACCAACCTACAGAGGCTTTAGGCATCCCTGCTTTATGATGTCGAGAAATAATTTCCGGAGTGACCCGCAAGAGGTCACATAGTTGAGTGCTTGATACGAGCAGATTGCCCGCAGCATCAAATTTCACTCTCGGTTTTGTGTCCGCCATAGGTGTACTCCTTTCTAAATTCGTCTTTCTACATTCAACAGGAAAATTTTTCTCACAGAGAGAGGACCATCGCGCGGGGGCGACCAGCGGCCATTTTTCGCCCTCGGAGTACCTTTTCCAAATTTTTATTTTCTCAATTAGGTATTATCATTGATACTCAATAAAAAAGGGTAGACCTCAACTAAGTAAGGTCTACCCCGGGGCAGTGCAGCAGGCAGACATATTGTGCGGGCCAGACACTGCCTGCTATCTACTACATTTACATTATATTAAATTAAGAGTGTGCCATTCTATGCCATCTTTTCAAATTCAGCTATTGCTTTCTTGTGAAGTCTGTGAACTTGTCGCCACGAATACCCTAGTTCGACAGCTATCTGCTCCCATGGCAATGCATTAATGTATCTGAGATTCAGTACATCTCTGTATTGTCCGTCAGTTATTTGGTTGATGACTTGCTTGACCTTGTTTCGAGAATCAATCAATTCATCCCATTCTCTGTTCAGCTCCTCCCTACATTCTTGTAAGTGCTTACTGATTCGTGGCATAGCATCTCCCGATTCACATATCTGTATAGCTTCTGAATGTAAATCTCGGTTAATCGCACCTAGCTGAATCTCTAACGCACGCATTCGCTGCTCAGTATGACGGACAGCTTGTAATTCTTCTATATCCATCATATGCGATAGTCCCCATATTTACTGATAATCATCTGTGCTCGTAGTAATCCGTCAATGTATCCGCTTTCACGAATTCTATCATATAGCATAGGTGATCTCAGTTGTCTATTCCGGGCTCGTATGATGGCAAGACTTAAATCTGACTGTACAGCACCTACAATCACATCTGCCCTGCTTCTACACTTTTGCATCATTTACCTCCATACGTTCGACAATATCCTCGATGGCTTCTACCATATCTGCTTTGCATTGCTCAACAGCGGTAAACATCTCCTCACACATGGCGTACGCATCATCACTCAGGTCATCATCTAATCTCTCGGCAACATTATCCTTAAGATTATCTACAACCTTAACTATATCCATGACAAGATAATACGTGTCATCTAGATAGTGCCCTTTGTTAATTAGTAGTCGCTCGACTTTTGTCATGTTCTTCCCTCTTTGCGATTTCCCGATTTAGATACCAACGGGCTTTTTTCAAATCCTTAATAGCATCGTCCTTATGACCAGCTCGGGATACATACTTTACTACATTACCCAATCGATACCCTAGTTTCTTGTCTTCGATGTAATCGATAACCTCGATATTTCCTTGTGTATAATGGCTTGGGTGGTTTATATCATCGCATTGATTAATTATGCGATTAGGAGATTTATCTGCTATAACTTTCTCTATTGTTAATCCTGATTGATTCGATACATTCTGTAATCGTTTTAGATTTTCGTTAGCTGCCAAACGTTTTAAAGTTTCATTAGCTGATAACTTAATAGGTGGTGGCGGTGGTCTATTAGGTCTCTCATACAATCTACCTGGGGTTAGCTCATATACTGTCTTGTGTTTTCGATTATCAATGATATCTATAACTTGAATAGTCGTGTAACACACTATTACTACGATTAATCCTGCCGTTATAAATTGACCCATATTAATCATCCTTTCTGTATTTATCGATTCTTGCTTTTAGGCTTTGCAGCACATATTCCTGTGCTCGGTCTTTTTGGGCTAGTGCATCCATCATATCCTCATCACGAGTTCCCTCACATATTAGATGATGGATAATTACCTTCTCCATTTGACCTTGGCGATGTAACCGCTTATTAGCTTGTTGATATAATTCAAGACTCCAGTTTAACCCGAACCATATTACGTGGTTACCACCGTCCTGTAAGTTAAGCCCGTATGCCGTACTAGCCGGATGTGCTAATAGAATATCAATCTCTCCAGCATTCCACGCTATCTCATCATCGGCACCCTTTAACTCACAGACTCGTAATTTAGTCTTAGCTAATGCTTCTTTTAACCGTTTACAGTCATGTTTAAAGTTGTAAAACACTAATGCAGGCTTTCCGTTTAACTGTTCTACGAGTTCCATAAATGCCTCAATTTTACAACCATGTATCTCGTGAACGTTTCTGTCGCCATCATATACAGCACCGTTCGCTAGCTGTTGTAGCTTTGTGGATAATGCTGCTGCACTCAAAGCTGTGATATCTTCGTCGGCTTCAATCAACTCTAATACAGATGTGCGCTCCATATCTTCGTAGGCTTTTTTGGCTTTCGCATCTAACTGCACATATTTAATATCGTTGATTACTGGAGGTAATTCCAAATAGTCATCAGCTTTCATGGATATGCATAACCCAGATATTGCCGTCATAATGCTGTCATTTGAATCGGATTTAGGTTTATAGGAGTACACCATTTCGCGTGACCTCTGATCGGGCTCGAAATAGTAATCTCTAAATCCTGTATACGTTTTCCCTAATGACTCGCCGCGGTCTAATAAATACACTTGCGCCCATAGGTCGATTAATCCGTTAGGGGCTGGCGTACCTGTTAACAACACCATGCGCTTGATATGGTTATGCATATAGGCTAATGACTTAAAACGCTTAGCTGTGTGGTTTTTAAAGGAACTAGATTCATCCACAACTACCATGTCAAACGGCCATACATTCTTGTAGTAATCAACTAACCACGTTACATTCTCTCGATTGATGATGTAGATGTCAGCAGGTGTGTTTAAAGCCTTAATACGCTTTTTCAAGCTGCCTAATACAGTAGATATCCTTAATATACCTACACCGTCCCATTTTCGCGCTTCTCGTTGCCATGTAGCCTCCGCTACTTTCTTAGGCGCTATGATTAGCACTTTACGGATGGCAAATCTAGAGTACTTCAATTCGTATATGGCTGATAACGTGATAATCGTTTTCCCTAAACCCATATCCAGGAATAACCCTATCTTATCTTGATTAACGGTCTTGTCGATACAATATCGTTGATACGCATGCGGATTAAACTGCATTACGATTTCACCCCGAATTCTTCTGTGAATTGTTCCAGATAACCAGACACGGCATCATCACCTTTTAACACAAATACTTTTTGATTTAGCTTTTGAAGTTCACGGGCTTGGACACCCTGCAACCGCGAAAGTACGCCTTTGGACGTCTTCAACTCTACGAAATGAATAACGCCGTTCGGCCATATGACGATACGATCAGGCACACCGACATTACCAGGGGATACAAACTTATACGCTTTACCTCCCGCGCGTTTGACGCCTACAACTAATTTTCTCTCGATATCCTTTTCTAACATTTCTCACCTCTGAAATTTTTAAACGTTAACATGTTTACATACGCGTATATGAGGGTTCAAATTAAGGCTGTAAAGGGCGTATTTTTTCTTAAAACTCTTTGTTTTGATATTTACCAGTATATAATGTTAACAATGTTAACCAACCTATATGAATATAGATAAATACTGACTTTATGCGTTAACATAGTACGTTAACATTCTCCGAATTCGTTAACATTCTAATGTTAACAAAAATACTGAGAATGTTAACGCTTAATTGAGAATGTTAACACTATAATTTCAGTTTTGACTCGTTGATTCTGAACCCTCTTTGATGCCCATATTCACCAAATCTCATCAACTGACTTCCGCCCATTGTATATGGGGAGTCCGCCAGTATTTGATTAATTTCCCTGGTCTCTATTTTCTTCATGCGACTTGGGTCGTTACCGAAACATTCCCACCATACCTCTGCCGCACAAATACGGTCACGATATACTAACTCTTGACCCTCGGCAGGTTTAGCATTCATGCTAAGATACGTCCTCCTGGCGCTCCGACTCATCACATTCCAATTTAAAGGTACCTTAATTAATAAAAACTCATTAATCAGTCCTGCTTTGGTGTTTGATTCCATATGCGCCTCTCTAGCCGCATCAGCCAGTTTTAGTACATTCGGGTCATCCTCGATAATGAGGCTTTCCCCGCTTTTATACCGATACAAAGCCTCCGCCCATAACTGGTCTACTTCCCCTGGAAGATTAACGAATATATTCTTTCGTGGAGTCGTCATCTCAAGATCAATAGGCCAAAATCGGCGATTGCCTGTAATATCCTTTAGGAATTCATATTGATTCGTGCTACCAAAGAACACACACTGCCGTGGATACTCTTGCGTACGTCGGCCATAGGCTTGACGAAATACATCTACTTGACGGCTTAGGAATTGCTTGGATGCATTTTCTTCAGCCCTCGAATACCCAGCCATTTCACCAGCTTCTATAATCCATTTACCTTGAATGCCTTCTGCAGCTTCCTTACCCTCAAAGGTATTTAATCCGTCAGCGTACCACTTCTTGCCCATTGTGCGGATAAGAGTACTTTTACCAATACCCTGACCGCCAATAAGAATTGGCATCGTGTCATACTTGCATCCAGGCTCAAACGCTCGCGCTACTGCCGCTGTAAATGACTTCCTAGCGGCTGCACGGGTATATACATTATCCTCAGCCCCTAAGTAGTCGATGAATATGGTATCTAATCGGGCAATGCCGTCCCAGGATAACCCGTTAAGGTAATCTAGTACTTCATTAAATCCATTTTGCTCAGCGCACATAATGAGGGCATCCATGATTTTATCTTTACCGGTGATATCATATTTATTTTCTAGGTACCACCGTAAGCCTGCATCATCTGCGTCTGTCCATATGCGAAGTCCTGGTGTTGGGTTCCATGGTAGGGCCCCTTTTGCCACGTATCTCGAACCAAATCTATCATAGGCAAGTCTACCGACAAGCGCCGGATCATGGTGCATGATTTTAAGCATATTATCTAGTGTGTTCTTAGGTCGACCATTCTCGTCGTACTTTAAAGTCGAACTTTTCATCCAGTCGACGTTCGTTAACGCATTAGGGTCGAGGTCGGATGTCTCAGCGTGAGCCGATACATCCGTGATAATATCAGCAAATACATTTGATGCCGATTCTCGGGCACGGGCCATGTTGAGTTCGTTAACGACTACCGTATCTTGCATAGCTAGTTTAGACATAGCCATGTAAGATGGTAGCTTATGCCCAGGTGTCCCATCCTTAGCAGTCTCGTCTAAGCTGTGGAACTTATGCAGCCGAATAAGGTCAAAGGCATTAACTAATTGACCACTACACGGGTCAGTATTATGGTGACTGAACAGGAATGTATCGTCATCATATATAACCGCCCCGGCTACTGTTGAGCCAGTAACGAACGTTAAGCGGTCCTCGCTGCCGTCAACATCGACATATGCATGAGGTATGAATTTATCAATCGCCTCACGGATACCATATATTCGACAAAAGGCACCTACGATACCTGGTTTTTCTCTCGGATCAGCTTGCTTTGCAAGTAGCTGCTTTTCATGCTGAGATGCTTCCTTACCCGGTACTTGTGGCCAAGAACGCACATCTCGCCAATCAGTGTATTGGCCGAGCATACCGTCAGCAGATAAGAATGCCTTATCGCCTACGTAATATACATATTGCGCATCGTTCGGGCATGATGGCCAATACATGAGCCGAGAAGCTTCGAACGTAGTTCCATCCATCATACCAATGCCGATGAGCTCCGCTAGCTTACGAGCAATAGGCTCATACTCATCAGGTGTCATCGTTCTATCAGTAGGGACGATAACACGTAACCGCGGACGGTGCACCGTATGAGAACGGGTTGAGTATATGACATAAGCCATGCCTAGGCTGTCAATCGTGCGAGCGACGTTCTCAGTTTCCCCAGGCGATATGGCATCCATATCAAGAGTAATCAAATCACGCCCAGACACGTTAATAGCTTTACGCTGCAGACCGTTTAACGTACCACCAACAAAGCCACCTATGTCCTTTAGCTTGCTTTTCTCAGATTTTGGCAATCTGTGGTATTCGTCCACGGTTTCTGTTGTACGAACGGGGATTTTGAGGCGTTCACAAAACTCGGACCACATCATCTCCGTACGGGTCCATTGCTTTGATGTGCGACTCGCACCGATACTGATGGTAATCAGTTTATCGTTTTGCAAGTGTATCCCCTCCTAATCTTTCATATAATAGTCATTAGTAAATCCTGCGGATGATAATAGCAGCCCGTCTGCCCAAGGTATGGCGATTGAGAATATAGCATTAACATCATTTAACGTAGATTCTGCATTCTCCTTGTTGATTTCAAGTACAGCCTCATCATGAATGTGCATGATAATTTGATATCCAGCATCCTCCAATCGGCGTAACGTTAACGCTAAACAATCGCGAGCGACTGCTTGTGTGATGTTTTCGACTAATTTGCCTCCATAGGTGCTTTCAGTAACCCATGCAGCATTTACCTTAGTCTTAAAATGTACAGCATCCTTACCGAATGCATTCTGCTTAATGCTTGGGCTAGGATAAAATAGCTTACGTCCACTCGGTAACTCAATCGTCATATAACGGTAACCGTATATTGGATCGATTTCCAAACGGAACATAATGCCGTGGTCAAGGCCTATAGGATTCCCGGTAGTAACGGTGTACACGGCCGCATTCTCAACGGCATACCATAAATCTCTTATTCTAGGCGATGCGTTGCGCCATAAATTTACGATTTCAGGTAATTCCTCCTCATGAAGTCCCATATCAAGAGCTCCCATGGCTTTTAATGCATTCACTCCGCCTTGATAGCCGAGTGCCAATTCAGCGACTTTACCTTTTTGTCTAAGATGACCATTCTCGCCATGCTTAACAACGGGAACACCAAACATCGATGATGCGGAAGCACAGTATATGTCTCCGCCCTCAGCGAATACACGTTGCCGCCAATGTTCTCCCGATAACCAAGCAATAACACGAGCCTCAATGGCTGAGAAGTCGGCCACACATAATGTATTGTCCTTTTCAGCAATAATTGAGGTACGAATTAATTGAGATAGCGTATCCGATACATCGCCATATAGAAGTTCTAACCCTTGACGGTTTTTGGTTTTAACGAGATGCCGAGCCGTGTCGAGGTTCTCGATGTAATTTCTCGGCAGGTTCTGCACCTGGATAAGACGACCCGCCCAGCGTCCGGTACGGTTGGCACCATAGAACTGCAATGTTCCCCTGAGTCGAAGATCAGCGCCCATGGCACTATCAGTCATCGTATATTTAGATACAGATGACTTAGCTAGCTTTTTACGAATCATAAGCACTTTTGTGGCAACGTCATCCGCATCCGTCAGAGCATCGGCCACAGTGTCCTTAGTTAACTTTTCAAGACTGACATTAGTATTATTGTTTAGCCAATCAAGTAATTGATTCCGGCTGTTAGGGTTGCTAAGTCCTGTAATTCGATAAGCCTCATTCATCAACATTTCTCGATTTTCCTCATCAACGTATAAGGCACCCTCAACCAATTCATGGTCAATGCGTACCCCTCTACTATTGATTTGGATATCAAGATACCAATCTTTCCACGTATCATCAGGTACAGGGAACGAGGCTAATCTGTGATAACATTCCATCTCAGTCACAACGTCCTGGCGGTTGTACTCGATAAAAGCATTCCATTTATCCGTATCGTGTCTAGGTAGATTACGTGTACGGCCACCATTTCGTTTGGTGGGCTTACATGGTGTACAAAAGTACTTGATAAGTGCTTTCCCTGATGTGTCCTTTTTCTTATCCTGAGGTAACCCCAGGGCCTTGCCGAGTAAGGCTAGGCCCATAGGATATCCTAAGTAGGCACCGTGAATCATCGTACACTGCCACTGATCAACAGATGTGAGTAACCCTGCACGATTTAGACACGTAATTTCAAATTGTGCATTGTAAGCGTGCTTGATTACATCTGAGTTTAATAAATCACGAATTACACTGTCAGGAATTACTCCTCCCTGCGCTAAATCTACAACTTCAACAGGACCAAAGTCGTAGGAATACGCAAATAGTAATATGGTGAAATCAGGCGATTCAGTATATTTGTACACTCCGAATGAGATATCGGTCGATGAATATGTTTCTATATCAATACTTAGATGCCTCATATCAGGCACCTATTAGTAAGGTTGACCAGTTACAGGGTTAATCCCTACAGGAGCTTGCTGCACGGATTGCTGAGGTGTCGTAGCATATGCCGGTTGTACATAACCTTGTTGAGCGGCTTGTTGTTGCACAGGTTGACCTGCTGCTACTGGAGCACCGGTATAAACATTAGCCGCACTACCTTGAGGTGCACCAAATACAGAGGATGCTGCAACAGGCATACTGCCCAACGCTTCACCATCGCGTACTTTTTGAACAGGGCCCAAACCACATCCAATACCAGTGGATTGATTGGAGTAGAAGAAGAATCGAACGAGTACATTGACATACATGCCGGAGTATACTTGCGTAGGATTTGTGAGAGGATTACCTTGAAGATCCACTACTTCAACTTTATAGCTAGCATCTTGTGCTGCTGTAAATACCCAATGGCCTTTACATTCAGGACCAAACTCCTTACCAGATTGTGTGTAACCATCACCGTCATGAATTGGTGTTTTTGGCTGTGCTGGAACACGTGCGCCGAATTTAGTACGAGCTGATTGGATAGCAGCTTCGATAGCATTCATGAGAGCTTGGTGTTGAGCTACATCAGTTTTAGGTAATAGAATAGTAGCTGAATATCTAGGTTTAGCACCAGGCTGTGTGGAGTTGGCCCAAGGTTCTAATAGATGGCAATAGGATACACGAACATTTTGCAATAATACTTCAGTTGGTTGTGGAACGAATGACATAATTAATTACCTCCATTATTATCATTAGATATATTAAAAATTTGCGCCGCAGTAGGTTGATTGGTAATCCGAGGGCGCTTATCGGATTCCTCAACTAGGGTAGGCTTGCCTGCTTTCTTAACTATCATGTCGCCTACCATATCATTAAATTGGGTTTTACCGATGGTCTTTTCCATCTGTGCCAATGTTAATGTCTTACGTTCATACAGAATGCTTTCATCGATACCAGCCTTGATTAAAGTATCAATAGCAGCATCAGTGTCTTGAAAGGCTCGACTACCACGACCCTCTACAGCTTTCCAGCCAGGGACTGTCACTCCGTTAAGGGATTCGGTGAGTGCGTAGTCTTTCATGTCTTCGAGCCAAGCAGCGACGTCTTTACCTCGACGAAGATATTCGCCGAGTTCTGTCATCGAGATAAGCCGAGGATCATGATTAGAAACTAGCGCACTGTGCAATGAGTCATTTGCCTCATATCGGGCTTTACATTGCTGCTTAGCCCTGCAGAATCTGCACCAGTCACCGGGTTCAAATTTACCGTTACCAGACATAGCCTCATCTGCGCGAGGTTTGACAAATGTATTACCCCAATCCAGTAATTCTGCCGTAGGGATTTCCCATTCGCTGATATTATTAACACGAGGCTGCACGATAGTCATTTTGACCGTATTGAACATATAGAGTAAGCTATATGCGTCAATCGCACCGAGGGCGTATAACATCATTTGCGGATTGTGTTCCGCATCAACGACTACCCCTTTTCCGTGCTTATAATCAACAATGTGCAAGGTATCCCCAGATAAGATGATACAGTCAGCCGTGCCGAATCCATCGGGTACATAACGACTAAAATCAACGCGTTTTTCAATGGCTACTACTGGAGTTGCCGTGCAACCTAACATAACACCTTTGACATATTCAAGGTATGTTTCCGAGGTATCGTCCATTTCTGGTTGCCACAATTCATCCTTTTTGATTTTGTTGAATTTGCGAGTGTATGTGGATTTAGCCATGGCCGTGGTATACTTCTGTAGTTTTAACTCACACAGTTCATGCGCCAGGGTTCCTTCCTTTGCATACACAGATGTACTATCGGGAAAGTTCTCCTCTAGGAGAGGGGCGGCTGTACAATGCAGCCACCGGTGTGACCCCGATGCGTTTAATAATGCATGTGATCGAGGTGCCATTAGATTCTTGCCCCCAATCCTCTAATTGCATTTACTAATTCAGGGTATCTCTCCTCAGGTACTTGACCCAAGTATTGAACACCGAATTGTGTCATTAATTGTTGCAATTCTACAGCCTTCCCTGCGTCAAGTAATGGTGCAAGCGCCGCTTGAATTTCAGGCAATGTATACTTCTTAACTTCTTGAGATACCGGAGCAGTAACAGGTGTTTGCACAGGTGCAGTAACTGTTTGTACCGGGGCATCAGTTGCCACGTTGATAGTTGGTGCTGTAACGGCTACTTGAGTAGGAGTAACTTGTACAGCTGCATTAGGTACCGTCATGGATACCGAGTTTGGTTGCACAGCTACTGTTGTAGTAGGTACACCTTGATTTGTATCTTGCGGAGCTAAATTAGATACGCACACGGACGGTGCTGCTACTGTAGATACCACTGTATCTACCATGCCAGGGGCTTTATCATCCATTGCTCTATCGCTATCTACAAAACTTTTGAATTGATTTAACACAGCTTTTAGCTGATTATATACATCTAGTACATTAACTCCTTGAACTTCAACTTTAATCATTCTTTAACTCCTCCTGAATATTAATAATTGATTGGTTGTAATACGATTCTTTTAACTCAAAACCTAAAGCCCTACGGCCCATACGAAGTGCCATAACTGGGACCGTACCAATACCAGCAAATGGATCAAGTACGATATCATTTGGATTACTCCACAATTCTATGCATCGAGCCACAGTATCTAGCTGCAGCGGGCAAATATGACGTTCGTCCTTATTGTCACGAGCTGCTTTATAATTCAGCGTATGCGTTTGGCGGATATCGGCCCATACAGGATTAGCATATCGGCGCCATACTTGATGGCTATATATAGGCTCTGTATTATATTTTTGCTTTTTATCAAACAAAACTGGATTGGGCGCAGGTCTTTCAATTCCTTTGATTCCCTCAGGTTCCTCTTGACCGAAGAACTGGATAAACCCCTCTGGATGCGCGATGGGCTCCGGATTGTCACCAGGTTTACGCAATGTCACGATGTAATCAGGCGCCCCCATTCTACACATGGCAGAATCTTTTACAATTTGCTTGTGTAAAAGCCCTAGCGCTTTTGTCCGAGTAGCCTCAATGAGAGGATCTTTCCAAATCGTGACTCGGGAATGCATCACGAATCCAGCATCCTGGAAGGCTCGAATAATGTCACCAGGAAAATCTTTCATTCCGATAACACCGTCCCTAGATTTTGTGAGTGGCAAATCCATACAATGGACCGATACTAATCGCCCTGGCATTATTACACGGTATAGTTCTGCGATTAAATACTTGAAATGTTGCCAAAACTCGATATCAGTAGATGAGTTGCCCATATCCCTATCAGAATTAGAGTAAACATACAAGCTACTAAATGGAGGGCTGAATATAGAGTAATGAACGCTATCATCAGGTAGCCCTTTCAGCACTTCTACTGAGTCACCATTATAGATTGCAAATCGGGACTCAATTAACTGATTTAGCACGTTCATGTTGTAGGTCCTCCTTTGATTTCTTATTTAGCGCTTGCAGCATTGCGACTCCAGCAAGGGAGGCTATAGCTATATTCATGCCTGCGTCAACAGCTAATTTAGTTAATTTGGCTGCTTTTAACTCATTGATGTGGATGACTCTTATGTTATGCCCCTTAGCATAAGCTAATTCCAAGTTGCACCCGGTTGAGTTCTCCCAGCCGTTGCACATTACGATTGCATCGCAGCCACTTAGAAGGTCAATGCACCAGTCTATGCCGGTATCATAATCGACCTTATCGTACAAATGCCCCAATATATGTATGGGTGATAGGAATATGTTATGGGTATCACTACCAAAAGGTTCTTTTATTGGAAATACGCCCATATTGTCCTGCAGCCACTTTAATACAGAGTCAGCATTCTTTTTATTTTTAGCCAATCCCCCGAATGGATGGCTTATGTAAATTTTAGTCATATAACAGCCCTCATTTCTGCCCAGTTAGGTAACACCATCGGCACACACGGATTGTATTCCGTTGATTCCCGTCTAGTTTTAGATAATTCAGTACGAACAGCGTCACGAGTAAGCGCAATCATAGCGTCCCTCATTTTTATAGCATCCGCTTCCTTACGTTCGATGTTTGCTTTAACCGCGCCCTCCTTTTCGGAGATTACGATATATGCGTTCACCTCATGCTTCTGGCCAAATCGCCAGCATCGGCGAAGTGCTTGATAATACTGTTCATAACTATCGGATAGCCCAACAAATATCATATTGTGGCAGTTTTGCCAGTTCATTCCGAATCCGGCGATACTTGGCTTTGTTACCAAACATTTTAGGAATCCAGAACCAAAACCTAACATCATGCCCTGCTTTCGAGTCGCCTTATCACTACCTTTGACGTCCTCTGCGAGATCAATCATTTCTTTCAAAGTAGTCGATTCATCATTAAGGTCGCACCACACTAGCCATTGCTCATTAGATGCATTGACTAAATCAGCTGCTGCTCTACATCTTGATTCAAGAGATGCTTTGCGAGCCCTGCGGCGTTCTAGTAATGATAAAGTAGGAACATCTTCACCAGTTTTATCAACGACGATTTCATGTACATGTAACTCAGGCAATTCATAGCCATCATCTTCATAACCTAGGGATGCCGGATTATCTAGCACTACTGCCCATGACGCCATCCACTCCCAAAAGGTATTCTCTGCATGGCCTTTTAATCGCCATTTAGCAGTATCACTACCATCGTGCGTGAAATACATAGATAGCATCTCATTACGGCTCATAATGCCGAGGAACTCCGCATGATTGCCAAGCTCCATATAGTCATTTGGTGCAGGTGTTGCCGTACATGCCAAGCGATATGGTGTATTACTGAATCGATTTATTAAATCTGTACGTACTTTACCAGTAAATGACTTTAGGATACTCGATTCATCAAGCACGACACCTATCAGATTATCGGTATTAAATCGGCCCAATTTCTCGTAATTCGTAATATTAACGCCTGGTACAATGTCATCATCGGATTCGCATATAGTCACAGGAATATCGAAACGTTCACCCTCGGATTGTGTTTGAGCGGCCACAGCTAGCGGTGCTAATATGAGTACTGATCCACCTGTATGTAAATAAATCTCATACGCCCAGGACAGCTGCATTAAAGTTTTACCTAATCCACAATCCGCAAATATGGCGGCTTTACCTTTTGCCAAGGCCCACTTAACGATATCTCGTTGAAAATCAAATAGGTGTTTGTTTAGCATACCTGTATCAATATCAAATCCGTGAGATTCTGACATTTTAGACTTGAGGTTGATGAAAGCGTTATAATTCAT

Protein sequences of DBSCAN-SWA_1

>NZ_CP019721|323512:342708|339353_339923_-|WP_077707727.1|DBSCAN-SWA
MIKVEVQGVNVLDVYNQLKAVLNQFKSFVDSDRAMDDKAPGMVDTVVSTVAAPSVCVSNLAPQDTNQGVPTTTVAVQPNSVSMTVPNAAVQVTPTQVAVTAPTINVATDAPVQTVTAPVQTPVTAPVSQEVKKYTLPEIQAALAPLLDAGKAVELQQLMTQFGVQYLGQVPEERYPELVNAIRGLGARI
>NZ_CP019721|323512:342708|329717_330104_-|WP_077707717.1|DBSCAN-SWA
MMDIEELQAVRHTEQRMRALEIQLGAINRDLHSEAIQICESGDAMPRISKHLQECREELNREWDELIDSRNKVKQVINQITDGQYRDVLNLRYINALPWEQIAVELGYSWRQVHRLHKKAIAEFEKMA
>NZ_CP019721|323512:342708|332415_332712_-|WP_077707722.1|DBSCAN-SWA
MLEKDIERKLVVGVKRAGGKAYKFVSPGNVGVPDRIVIWPNGVIHFVELKTSKGVLSRLQGVQARELQKLNQKVFVLKGDDAVSGYLEQFTEEFGVKS
>NZ_CP019721|323512:342708|325401_326883_-|WP_077707713.1|portal|DBSCAN-SWA
MNILDKVIAYFNPERAARRAYFRSSLERGYDAASTDRLSGDWMPVFGTAEQVASGQRDLIRGRARAAELNSDLAESVVLALLRNVVGTGIKPQCKIKTRAGKLNERLNKKIEEAWSDWVDKENADIRGISTFYELQEMALRRMVYDGEILVNMTSEGADIPLSLQLIEGENIGAVSVSENGNSIVNGVEVNKYGRPIAYHVFQTDPLGIRSFNEARLPSNRAFLLHKPRRPSELRGVSMLALVLKRIHDVDEYMDADLIAARVAACFGAFVTSNTGGNPMVASKIDSKGKKVRSMAPGIIQHLRAGESISFAEPKRNAGTASEYSATQTRRIASGMGLSADIVTRNISGNFSAARQNMLEDQQSFKQMQRFIIEHFCMPVWRAFIEACYLKGIIPANDYAANPKLYKKVAWLAPGWSWIDPVKEVNANKEAIKAGLTTLEDVCSASGKDWEEVLEQRKLEQDRIKELGVALDMNGDITNLADDNATDMKGDDS
>NZ_CP019721|323512:342708|337447_338167_-|WP_077707725.1|DBSCAN-SWA
MSFVPQPTEVLLQNVRVSYCHLLEPWANSTQPGAKPRYSATILLPKTDVAQHQALMNAIEAAIQSARTKFGARVPAQPKTPIHDGDGYTQSGKEFGPECKGHWVFTAAQDASYKVEVVDLQGNPLTNPTQVYSGMYVNVLVRFFFYSNQSTGIGCGLGPVQKVRDGEALGSMPVAASSVFGAPQGSAANVYTGAPVAAGQPVQQQAAQQGYVQPAYATTPQQSVQQAPVGINPVTGQPY
>NZ_CP019721|323512:342708|335470_337435_-|WP_077707724.1|DBSCAN-SWA
MRHLSIDIETYSSTDISFGVYKYTESPDFTILLFAYSYDFGPVEVVDLAQGGVIPDSVIRDLLNSDVIKHAYNAQFEITCLNRAGLLTSVDQWQCTMIHGAYLGYPMGLALLGKALGLPQDKKKDTSGKALIKYFCTPCKPTKRNGGRTRNLPRHDTDKWNAFIEYNRQDVVTEMECYHRLASFPVPDDTWKDWYLDIQINSRGVRIDHELVEGALYVDEENREMLMNEAYRITGLSNPNSRNQLLDWLNNNTNVSLEKLTKDTVADALTDADDVATKVLMIRKKLAKSSVSKYTMTDSAMGADLRLRGTLQFYGANRTGRWAGRLIQVQNLPRNYIENLDTARHLVKTKNRQGLELLYGDVSDTLSQLIRTSIIAEKDNTLCVADFSAIEARVIAWLSGEHWRQRVFAEGGDIYCASASSMFGVPVVKHGENGHLRQKGKVAELALGYQGGVNALKAMGALDMGLHEEELPEIVNLWRNASPRIRDLWYAVENAAVYTVTTGNPIGLDHGIMFRLEIDPIYGYRYMTIELPSGRKLFYPSPSIKQNAFGKDAVHFKTKVNAAWVTESTYGGKLVENITQAVARDCLALTLRRLEDAGYQIIMHIHDEAVLEINKENAESTLNDVNAIFSIAIPWADGLLLSSAGFTNDYYMKD
>NZ_CP019721|323512:342708|330281_330536_-|WP_077707719.1|DBSCAN-SWA
MTKVERLLINKGHYLDDTYYLVMDIVKVVDNLKDNVAERLDDDLSDDAYAMCEEMFTAVEQCKADMVEAIEDIVERMEVNDAKV
>NZ_CP019721|323512:342708|338169_339354_-|WP_077707726.1|DBSCAN-SWA
MAPRSHALLNASGSHRWLHCTAAPLLEENFPDSTSVYAKEGTLAHELCELKLQKYTTAMAKSTYTRKFNKIKKDELWQPEMDDTSETYLEYVKGVMLGCTATPVVAIEKRVDFSRYVPDGFGTADCIILSGDTLHIVDYKHGKGVVVDAEHNPQMMLYALGAIDAYSLLYMFNTVKMTIVQPRVNNISEWEIPTAELLDWGNTFVKPRADEAMSGNGKFEPGDWCRFCRAKQQCKARYEANDSLHSALVSNHDPRLISMTELGEYLRRGKDVAAWLEDMKDYALTESLNGVTVPGWKAVEGRGSRAFQDTDAAIDTLIKAGIDESILYERKTLTLAQMEKTIGKTQFNDMVGDMIVKKAGKPTLVEESDKRPRITNQPTAAQIFNISNDNNGGN
>NZ_CP019721|323512:342708|331033_332416_-|WP_077707721.1|DBSCAN-SWA
MQFNPHAYQRYCIDKTVNQDKIGLFLDMGLGKTIITLSAIYELKYSRFAIRKVLIIAPKKVAEATWQREARKWDGVGILRISTVLGSLKKRIKALNTPADIYIINRENVTWLVDYYKNVWPFDMVVVDESSSFKNHTAKRFKSLAYMHNHIKRMVLLTGTPAPNGLIDLWAQVYLLDRGESLGKTYTGFRDYYFEPDQRSREMVYSYKPKSDSNDSIMTAISGLCISMKADDYLELPPVINDIKYVQLDAKAKKAYEDMERTSVLELIEADEDITALSAAALSTKLQQLANGAVYDGDRNVHEIHGCKIEAFMELVEQLNGKPALVFYNFKHDCKRLKEALAKTKLRVCELKGADDEIAWNAGEIDILLAHPASTAYGLNLQDGGNHVIWFGLNWSLELYQQANKRLHRQGQMEKVIIHHLICEGTRDEDMMDALAQKDRAQEYVLQSLKARIDKYRKDD
>NZ_CP019721|323512:342708|330507_331032_-|WP_077707720.1|DBSCAN-SWA
MGQFITAGLIVVIVCYTTIQVIDIIDNRKHKTVYELTPGRLYERPNRPPPPPIKLSANETLKRLAANENLKRLQNVSNQSGLTIEKVIADKSPNRIINQCDDINHPSHYTQGNIEVIDYIEDKKLGYRLGNVVKYVSRAGHKDDAIKDLKKARWYLNREIAKREEHDKSRATTN
>NZ_CP019721|323512:342708|326879_327086_-|WP_077707714.1|DBSCAN-SWA
MSAREDLERIRTIIEEIETNGYAEMSVGGKRFKTHDLPTLYARERELMVRVDDEECNSTTSYVSWERR
>NZ_CP019721|323512:342708|341334_342708_-|WP_077707730.1|DBSCAN-SWA
MNYNAFINLKSKMSESHGFDIDTGMLNKHLFDFQRDIVKWALAKGKAAIFADCGLGKTLMQLSWAYEIYLHTGGSVLILAPLAVAAQTQSEGERFDIPVTICESDDDIVPGVNITNYEKLGRFNTDNLIGVVLDESSILKSFTGKVRTDLINRFSNTPYRLACTATPAPNDYMELGNHAEFLGIMSRNEMLSMYFTHDGSDTAKWRLKGHAENTFWEWMASWAVVLDNPASLGYEDDGYELPELHVHEIVVDKTGEDVPTLSLLERRRARKASLESRCRAAADLVNASNEQWLVWCDLNDESTTLKEMIDLAEDVKGSDKATRKQGMMLGFGSGFLKCLVTKPSIAGFGMNWQNCHNMIFVGLSDSYEQYYQALRRCWRFGQKHEVNAYIVISEKEGAVKANIERKEADAIKMRDAMIALTRDAVRTELSKTRRESTEYNPCVPMVLPNWAEMRAVI
>NZ_CP019721|323512:342708|323512_325402_-|WP_077707712.1|head|DBSCAN-SWA
MGKFAKNQLLGKYAREAQITNIEANDDRTVELSFSSEEPYERWFGTEILCHDEGCVNLDRFNNGLGTLLFNHNRSAVVGHIDKVWIEDNRGKAIVRFDEDDESEKIYQKVLKGTLQGVSVGYDISRYEELIDFDSKSSNGRFTGPGYVITGWEPLEISIVSVPADPSVGVGRSVDDNEEEPMKGDAKAKGTEQNVPQVVPEVPESGVKGFNADDAKKLIAAERERVSTITSLCRDFEVDGVDEFIKSGKSVAEVREAVMDALRERNKPVSVKVGEADSDKFRMAMQDALMMSAGIPVANPAPGANELRSMSLMELARESLVREGLTANYADRLELAREAINSTSTFPIALSNVANKSLVQGYETAPTTFDAWTGKGSNRDFKPAKRILLSETAELKLVPEGGQFKDSKLEEAGNDVRVLTYGRTFSLTRQAIINDDLGVFKDIASKFGRSAKDTINSMVYGLLTGNTVLSDGKALFGTDRGNLAATGAELSVASLSAGVAAMRRQKHIGENRNLNIAPTYLIIPPELEALAYELVKSTVDPARSNGTVNPFGGRFTIVVDAALTDPHAWYLAARPTDVQTIEVTYLNGVETPRLETQTGFKVDGIEYKVAMDCNATALDFRGLYKNPGK
>NZ_CP019721|323512:342708|332983_335458_-|WP_077707723.1|DBSCAN-SWA
MQNDKLITISIGASRTSKQWTRTEMMWSEFCERLKIPVRTTETVDEYHRLPKSEKSKLKDIGGFVGGTLNGLQRKAINVSGRDLITLDMDAISPGETENVARTIDSLGMAYVIYSTRSHTVHRPRLRVIVPTDRTMTPDEYEPIARKLAELIGIGMMDGTTFEASRLMYWPSCPNDAQYVYYVGDKAFLSADGMLGQYTDWRDVRSWPQVPGKEASQHEKQLLAKQADPREKPGIVGAFCRIYGIREAIDKFIPHAYVDVDGSEDRLTFVTGSTVAGAVIYDDDTFLFSHHNTDPCSGQLVNAFDLIRLHKFHSLDETAKDGTPGHKLPSYMAMSKLAMQDTVVVNELNMARARESASNVFADIITDVSAHAETSDLDPNALTNVDWMKSSTLKYDENGRPKNTLDNMLKIMHHDPALVGRLAYDRFGSRYVAKGALPWNPTPGLRIWTDADDAGLRWYLENKYDITGKDKIMDALIMCAEQNGFNEVLDYLNGLSWDGIARLDTIFIDYLGAEDNVYTRAAARKSFTAAVARAFEPGCKYDTMPILIGGQGIGKSTLIRTMGKKWYADGLNTFEGKEAAEGIQGKWIIEAGEMAGYSRAEENASKQFLSRQVDVFRQAYGRRTQEYPRQCVFFGSTNQYEFLKDITGNRRFWPIDLEMTTPRKNIFVNLPGEVDQLWAEALYRYKSGESLIIEDDPNVLKLADAAREAHMESNTKAGLINEFLLIKVPLNWNVMSRSARRTYLSMNAKPAEGQELVYRDRICAAEVWWECFGNDPSRMKKIETREINQILADSPYTMGGSQLMRFGEYGHQRGFRINESKLKL
>NZ_CP019721|323512:342708|327101_328985_-|WP_077707715.1|terminase|DBSCAN-SWA
MALSKNTSKATHAQASTRRKSKPREKVSPKVDWFPEELEAFKPPERYTVSEWADRYRVLTNISAEPGRWRTARTPYLKEPMDKFTDPLIESISLCFGAQIGKTETELNMIGYALHQTVSPTMMVYPTDTIAKFASDKRVQPMIRSVEPLADMYDESSKLLELDFVNGNYMVLVGANSPSSLSSRSIKYLFFDEIDKYPAFSGKEANPIKLAEERTKTFVDKKIVRVSTPTIESGNIWQSYMGANERKQYYVPCPHCGVSQTLKFKQIKWPEEHHGNADMIRDTAYYECEHCKHRIDDKHKMDMLRQGEWLAVNESQVRVVRSVAYQLSSLYSPWVTFGDVAYEFVKSKDTPSELMNFINSWLAEPWKSAKTKSTQNLVFTQSEVPRGVVPQHAPLLIASVDVQQDHFWWEVRAYAHGVSSYLVDYGQASSWADLTEILIDREYPSEYGEARKIVRAGIDSGYRTDEVYQYCAQYPEVCVPVKGDSSHSPLAPPYKMSSIEKGVIGGMKLYVVNTDYWKDFIFARMVRPANEPGTIHLFKDCPEEYSEHLRSEEKQEIRNVKTGAVTVQWKPLTSHPTNHLLDTCVYNAMVADSVGVKYLPEYNLDTDEEDEDTDVEDFNADSRGWFS
>NZ_CP019721|323512:342708|340855_341338_-|WP_077707729.1|DBSCAN-SWA
MTKIYISHPFGGLAKNKKNADSVLKWLQDNMGVFPIKEPFGSDTHNIFLSPIHILGHLYDKVDYDTGIDWCIDLLSGCDAIVMCNGWENSTGCNLELAYAKGHNIRVIHINELKAAKLTKLAVDAGMNIAIASLAGVAMLQALNKKSKEDLQHERAKSVN
>NZ_CP019721|323512:342708|339915_340881_-|WP_077707728.1|DBSCAN-SWA
MNVLNQLIESRFAIYNGDSVEVLKGLPDDSVHYSIFSPPFSSLYVYSNSDRDMGNSSTDIEFWQHFKYLIAELYRVIMPGRLVSVHCMDLPLTKSRDGVIGMKDFPGDIIRAFQDAGFVMHSRVTIWKDPLIEATRTKALGLLHKQIVKDSAMCRMGAPDYIVTLRKPGDNPEPIAHPEGFIQFFGQEEPEGIKGIERPAPNPVLFDKKQKYNTEPIYSHQVWRRYANPVWADIRQTHTLNYKAARDNKDERHICPLQLDTVARCIELWSNPNDIVLDPFAGIGTVPVMALRMGRRALGFELKESYYNQSIINIQEELKND
>NZ_CP019721|323512:342708|328890_329427_-|WP_077707716.1|DBSCAN-SWA
MADTKPRVKFDAAGNLLVSSTQLCDLLRVTPEIISRHHKAGMPKASVGWWNLREVLVYLGQAKGDNAKSKSASTRKLEAEADYKEAKAAREKKMLDVLNGEYVPRADVAQAWANRILELKTSFTKLGKRIGSEFTDPEERARVEKVVNGLVEEYLESYARAGEYTPKVKATGKGKSKG

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_077707712.1|323512_325402_-|head	Mu-like prophage major head subunit gpT family protein	A0A1W6JT88	Pseudomonas_phage	1.5e-60	43.5
WP_077707713.1|325401_326883_-|portal	phage portal protein	G8CLA3	Synechococcus_phage	1.1e-58	29.5
WP_077707714.1|326879_327086_-	hypothetical protein	NA	NA	NA	NA
WP_077707715.1|327101_328985_-|terminase	phage terminase large subunit family protein	A0A2K9V301	Faecalibacterium_phage	2.6e-116	42.3
WP_077707716.1|328890_329427_-	hypothetical protein	NA	NA	NA	NA
WP_077707717.1|329717_330104_-	DUF1492 domain-containing protein	A0A218MNE1	uncultured_virus	2.1e-09	40.5
WP_077707719.1|330281_330536_-	hypothetical protein	NA	NA	NA	NA
WP_077707720.1|330507_331032_-	DUF3310 domain-containing protein	A0A1B1IWM3	uncultured_Mediterranean_phage	1.1e-13	61.3
WP_077707721.1|331033_332416_-	DEAD/DEAH box helicase	S5MA26	Brevibacillus_phage	1.7e-136	51.3
WP_077707722.1|332415_332712_-	VRR-NUC domain-containing protein	A0A2I6PE31	Staphylococcus_phage	8.7e-11	37.9
WP_077707723.1|332983_335458_-	virulence-associated protein E	A0A1S7FZ15	Listeria_phage	7.7e-185	42.2
WP_077707724.1|335470_337435_-	DNA polymerase	H7BVQ1	unidentified_phage	1.2e-177	50.3
WP_077707725.1|337447_338167_-	DUF2815 family protein	A0A2K5B2A9	Erysipelothrix_phage	8.1e-18	36.9
WP_077707726.1|338169_339354_-	DUF2800 domain-containing protein	H7BVP9	unidentified_phage	4.3e-93	46.8
WP_077707727.1|339353_339923_-	hypothetical protein	NA	NA	NA	NA
WP_077707728.1|339915_340881_-	site-specific DNA-methyltransferase	F4YCV3	Synechococcus_phage	2.6e-96	56.3
WP_077707729.1|340855_341338_-	DUF4406 domain-containing protein	NA	NA	NA	NA
WP_077707730.1|341334_342708_-	helicase	F4YCV3	Synechococcus_phage	1.3e-133	52.3

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP019721|1045906:1051895|DBSCAN-SWA
TATGAAGGTCGGTATTATCATGGGCAGCAAGTCTGACCTGGACACAATGAAAAAAGCATCTGCCGTACTTGATGAATTTAACATTCCCTATGAAATGGTTATTGCCTCAGCTCATCGTACCCCAGAGGCTGTGAAGAACTTTGTCACACGACTTGAAGATGAAGGGGCTATCGCTTTTATTGCTGGTGCTGGCGCGGCGGCTCATTTACCTGGTGTGGTGGCGAGCTTCACTACATTACCTGTTATCGGCATTCCTCTTAATGCAACGGCTCTAAAAGGCATTGATTCTTTGCTTGCTATCGTTCAAATGCCATCTGGTATGCCTGTAGCAACTATGGCTGTAGATGGTGCTAAAAATGCAGCGCTCTTTGCAGTACAAATTGGAGCAGCTTTCAATAAAGACCTGAAAGAACAATATCAACTATATCGTAAAGATATGGCTGAAAAAGTCTTAGCAGACAATGCAGAATTACAAGGTGCTATTCATATTTAATCATGTAAATCATCGGCGATTAAATATTGGTTAAGAAAAACAGTTTATTTAGATATCTATTACATAGTTTGTATCATTAATTAGTTTGTATCATTAATTTATGATAAAGGAGAAAGATCATGGCTAACATCGATTTGGAAAAATTAACATTATTGTACGAAGGCAAAGCAAAACAAGTATATGCAACAGATAACAAAGATGAGTACATCGTTCATTACAAAGATGATGCCACTGCATTTAATGGCGAGAAACATGATACCATTCTTGGAAAAGGTGTTTTGAACAATAAAATTTCCTCTTTCTTCTTTGAATTGTTGAAAAAAGAAGGCGTACCAACTCATTTCGTTCGTCGTGAAGATGATCGCAACCAAACAGTACTTGCATTGAAAATAGTTCCTCTTGAAGTTATTGTTCGTAATATTGCGGCTGGCTCTATGGCTAAACGCTTTGGCATTGAAGAAGGAACTCCACTTAAACATCCAATCCTTGAATTCTGCTACAAAAATGATGAATTAGGCGATCCATTTGCCAATGAATCCCAAATCACAGCACTTGGTTGGGCTACTCAAGAACAACTTGATGTAATTTCTACAATTACTTTAAAGGTAAATGATATATTGAAGAAATTTTTGGCTACTAAAAATGTGACCCTTGTAGATTTCAAGGTAGAATTTGGTACCCATAATGGTGAAGTTTTATTGGGTGATGAAATTTCTCCTGATACATGCCGTTTCTGGGATGCTACAACTGGTGAAAAACTTGACAAAGACCGTTTCCGTCGAGATCTTGGTAATATTGAAGAAGCATATAAGGAAATGTTATTCCGTCTTACAGGTGAGCGTGCCTAATAGGGGGAAGATGAACTACGATTCTGTTTTTGACAAATGGCACGAAGAGTGTGGTGTATTCGGCATCTATGATAGGACCGTTGATGTAGCACGCTATGTATATTGGGGGCTATTTGCTCTCCAACATCGTGGTCAAGAAAGTGCGGGCATTGCTGTTACCGATGGTCATGATGTAGAACTGAAAAAAGGCATGGGCTTGTTGACCGAGGCTATCAAAGAATTACCATCTTTGCCAAGCTATATGGGGACTGGTCATGTGCGGTACTCTACGACCGGTTCCAATAATCCGCGTAATATCCAGCCTTTGGTTATTCACTACCAAGGCGGTCAAATTGCGGTGGCTCACAATGGAAACTTAACGAATGCCTTATCTATTCGAAAACGTCTTGAAGCCGATGGTTCCATCTTTCAAACGACGATGGATTCTGAGGTTATCGTAAACTTGATAGCCCGTTCTAAAGCAGAAACACAAGCGGAACGGATTGCCGATGCGGCGCGTCAAATTGAAGGGGCGTTCTCTTTAGTCATTACTACGAACGACTCTTTAGTAGGTGTACGAGACCCTCAAGGATTTAGACCACTTTGTTTAGGTAAAACTGAAAATGGTTATGTGCTCTCTAGTGAAAGCTGTGCTTTTGATGCGATTAAGGCAGAGTTTATTCGTCATATAGATCCTGGTGAAATGGTTATCATCGATGACTCTGGTGTGCGTAGTACAATCTATGCGGAACCAGAAAAAATCGATAAAAAACTTTGCGTCTTTGAATACATTTATTTTGCACGTGGCGATAGTCATATCGATGGTCAATCCGTATATCAATCTCGGCTAAATATGGGCCGCGAACTATATAACGAAACTAAGTATGATGCGGACATCGTAATGTCCATTCCGGATTCCGGTACAACAGCTGCATTAGGTTATGCTCGTGCATCGGGTATCCCTTTTGCAGAAGGTTTAGTTAAGAACCGTTATAGCGGTCGTACCTTTATTAAACCAAATCAAGAGGAACGAGAATTAGCTGTTCGTATGAAGCTAAATGCATTGCCACATATTGTTGGAGGTAAGCGTATCGTCCTTATTGATGATTCTATTGTGCGCGGTACTACGAGTGGTATCATTGTAAAAATGCTAAAAGAGGCTGGTGCTAAAGAGATTTATATGTGTATTAGTTCTCCAACTATTGAGTATTCCTGTCACTATGGCATTGATACATCGGTGCGTAAAGAACTTATAGCAGCTACTCATACAGTGGATGAAATTAAAGATTTTATCAAGGCTGATAAATTACATTACTTGTCTCGTGAAGGCCTATGTCGTGCTGTATCTGATGTAAAGCCAGATGATTTATGTTTTGCATGTTTCAATGGTGATTATAGTGTAGCGGTTCCTGCGGATCAAGAGGAAGGGGTCAAATATGTGCTCGAATAAAACTAGTTTAACCTATCGTGATGCAGGTGTTGATATCGATGCAGGTAATCGCGCCGTAGAACTGATGAAAGAATCTGTTAAACGCACGTATATACCGGGTGTTGTTGGTGATTTAGGTGGTTTTGGGGGACTCTATTCCTTAGCTGGTCATGCTATGTCTGATCCTATGCTCGTATCTGGTACAGATGGGGTGGGCACCAAATTACGTCTCGCTATTATGATGGATAAACATGATACTATCGGTCAAGACTGTGTAGCTATGAGTGTTAATGATATCCTCGTACAAGGTGCTACACCTTTATTCTTCCTTGATTATATTGCGGTTGGCAAACTAGAGCCTGTAAAAGTGGCGGATATCGTACGCGGTGTAGCTGAGGCGTGCGAAGAATCAGGCTGCGCCTTACTAGGCGGTGAAACTGCTGAGATGGCAGGTTTCTACGATGATGAGGATTATGATGTAGCTGGTTTTGCCGTTGGTATCGTAGATCGTCCTAAATTGATTACTGGTGAAAGTATTAAAGCTGGTGATGTGATTTTGGGCTTGCCATCTTCTGGAGTACATTCCAACGGCTTCTCCTTGGTTCGTAAAATTGTATTCGATCATAAACAGTTGTCTATTGATACAGAAATTCCAGAATTTGGTAAAACTTTAGGCGAAGAATTATTAACGCCTACTCGTTTATATCCTAAAGCTGTATTACCGTTGATTAAAGAAGATTTAATTAGAGGTATGGTTCATATTACGGGCGGCGGTTTCTATGAAAATATTCCTCGCGTCTTACCGGCGGGAGTAACGGCAGAGATCGATTGTGATACATGGCCTCGCCTTCCAGTTTTTGAAAAGCTACAAGAATGGGGCAATGTAGATTGGCATGAAATGTACCGTACTTTTAATATGGGCATTGGCATGATCCTCATAGTGGACACTGCGGATGTGGATCGAGTAAAGGCAAATCTTGAAAGTCGTAATGAAGCGGTTTATGAAATTGGTCATATCGTTAAAGGCGAAGGTCCAGTTGTTGTAAAAGGGGCGGTATTTAATGACTAGTTCCGTAGCTAGAAAACGTCTAGCTCTATTCGCAAGCGGTAGAGGCTCCAATGGGGAAGCCCTTTATAAAGCCATGCAAGAAGGATATATTAATGGTGAGTTTGTAGTTATCATTACAGATCACGGTGATGCAGGGATTGTTGAACGTTCTAAACCTTGGAATATTCCACTCATTGTCATCGAGCGTAGCGACTATGATTCTAAAGCTAGCTTTGAACAAGCCCAGTTAGATGCGTTAGAGCCCTATAAGGTAGATGGTATCGTTTTGGCTGGATATATGCGTATTGTAGGGGCTCAACTTATTGAGCACTATGAGCATAGAATTTTAAATATCCATCCTGCCTTGTTGCCATCTTTTCCGGGACTACATGGGCATCAACAAGCTATCGATGCGGGCGTAAAGGTAACTGGTTGTACGGTACACTTTGTTGATGCCGGAATGGATACAGGTCCTATTATCATGCAGAATACAGTTCCTCTATTACCAGACGATACAGAGGATACCCTGAGTGATAGATTATTGCCTATTGAACATAAAACATATAAAGAGGCGTTACGACTATTTTGTGAGGATAAGCTCACTATAAAAGGTCGTACGGTTTATATTGAAGATTGATATGTGTAAGCAAATGGAGAGGTTACATGATTAAAAATGCACTGCTTAGTGTTTCTGATAAAACGGGTATTGTAGATTTTGCAAAAGGTTTAGTTGACTTAGGTGTAACCATTTATTCTACAGGTGGTACGCTTAAGGCCATAACCGAAGCAGGTATTCCGGCAAAATCGGTAGAGTCTTTGACAGGTTTTCCAGAAATGATGGATGGCCGAGTAAAAACTTTACATCCTAACGTGCATGGTGGTATTTTGGCTATCCGTGATAATGCGGAGCATAAACAAGCTATGGCAGAACATGGTATCGAACCAATCGACCTTGTTGTGGTGAATCTTTACCCGTTCCGTGAAACCATTGCAAAACCTAATGTATCCTTAGAAGAGGCCATCGAAAATATCGATATTGGTGGTCCTACGATGGTTCGTTCTGCCGCAAAAAATCATGCGTACGTAGGCATCGTAGTAAATCCAAATCATTACGATGAAATCATTACGATGCTCAAGGATCAAGGTGAATTGACTAAGGAATATCGCTTTGGACTTGCCAAAGAAGCCTTTGCTCATACAGCGGCTTACGATGTGGCCATCGCTAATTATATGAGTGGAATCTTGAATGAAGGTCCTACACCTCCTGAATATCTGAGCGCTTATGAAAAGGTAACAAATCTTAGATATGGAGAAAATCCGCATCAACAAGCAGCATTCTACAAAGAAATTGGTACAGCTCATGGCATGGGGGCTTTAAAACAACTACATGGCAAAGAGCTTTCCTATAATAATATTGTAGACATGGAAGCGGCATGGAATATGGTATGGGAATTTACTAATCCAGCTGCATGTATCATTAAGCATACGAACCCATGTGGTGCAGCTACTGCAGCTACATTACATGATGCATATGTAAATGCTTATGAAGCGGACTCCGTATCTGCCTTTGGTGGCATCGTAGCCTTAAATCGTGAAGTAGATGCAAGTACAGCGGAGGAAATGAGCAAAATTTTCTTAGAAGTTATTATGGCACCTGCTTTCACAAAAGAAGCATTAGAAATCCTTGAAGCTAAGAAGAATATTCGCCTCATCGAGCTATCTAAGCCGGAATCTGGCCAAGTGACAGTGAAAAAGGTGTCTGGTGGTTTATTAGTGCAAACAGAAGACGATCTGGTAGAAGACCGCGCCAATTATAAAGTTGTTACGAAGGTACAACCGACAGAGGAACAATGGAAAGCCCTAGAATTTGCATGGAAACTTGTAAAACATGTAAAGTCCAATGCTATTTTGATTTCTAATGAAAAACGTACCCTTGGAGTTGGGGCGGGTCAAATGAATCGCGTAGGCTCTGCAAAAATTGCCCTTGAACAAGCCGGGGAAGCCGCTAAAGGCGCTGTTTTGGCATCCGATGCATTCTTCCCCTTTGGCGATACCGTGGAAACAGCGGCAAAACATGGCATTGCAGCTATTATTCAACCAGGTGGCTCTATTCGCGATGAAGAGTCTATCAAAGCGGCTGACGAAGCGGGTATTGCCATGGTATTTACAAACATTCGTCACTTTAAACATTAA

Protein sequences of DBSCAN-SWA_2

>NZ_CP019721|1045906:1051895|1046532_1047246_+|WP_038149765.1|DBSCAN-SWA
MEKLTLLYEGKAKQVYATDNKDEYIVHYKDDATAFNGEKHDTILGKGVLNNKISSFFFELLKKEGVPTHFVRREDDRNQTVLALKIVPLEVIVRNIAAGSMAKRFGIEEGTPLKHPILEFCYKNDELGDPFANESQITALGWATQEQLDVISTITLKVNDILKKFLATKNVTLVDFKVEFGTHNGEVLLGDEISPDTCRFWDATTGEKLDKDRFRRDLGNIEEAYKEMLFRLTGERA
>NZ_CP019721|1045906:1051895|1048661_1049723_+|WP_077708110.1|DBSCAN-SWA
MCSNKTSLTYRDAGVDIDAGNRAVELMKESVKRTYIPGVVGDLGGFGGLYSLAGHAMSDPMLVSGTDGVGTKLRLAIMMDKHDTIGQDCVAMSVNDILVQGATPLFFLDYIAVGKLEPVKVADIVRGVAEACEESGCALLGGETAEMAGFYDDEDYDVAGFAVGIVDRPKLITGESIKAGDVILGLPSSGVHSNGFSLVRKIVFDHKQLSIDTEIPEFGKTLGEELLTPTRLYPKAVLPLIKEDLIRGMVHITGGGFYENIPRVLPAGVTAEIDCDTWPRLPVFEKLQEWGNVDWHEMYRTFNMGIGMILIVDTADVDRVKANLESRNEAVYEIGHIVKGEGPVVVKGAVFND
>NZ_CP019721|1045906:1051895|1045906_1046398_+|WP_077708108.1|DBSCAN-SWA
MKVGIIMGSKSDLDTMKKASAVLDEFNIPYEMVIASAHRTPEAVKNFVTRLEDEGAIAFIAGAGAAAHLPGVVASFTTLPVIGIPLNATALKGIDSLLAIVQMPSGMPVATMAVDGAKNAALFAVQIGAAFNKDLKEQYQLYRKDMAEKVLADNAELQGAIHI
>NZ_CP019721|1045906:1051895|1049715_1050339_+|WP_077708111.1|DBSCAN-SWA
MTSSVARKRLALFASGRGSNGEALYKAMQEGYINGEFVVIITDHGDAGIVERSKPWNIPLIVIERSDYDSKASFEQAQLDALEPYKVDGIVLAGYMRIVGAQLIEHYEHRILNIHPALLPSFPGLHGHQQAIDAGVKVTGCTVHFVDAGMDTGPIIMQNTVPLLPDDTEDTLSDRLLPIEHKTYKEALRLFCEDKLTIKGRTVYIED
>NZ_CP019721|1045906:1051895|1050365_1051895_+|WP_077708112.1|DBSCAN-SWA
MIKNALLSVSDKTGIVDFAKGLVDLGVTIYSTGGTLKAITEAGIPAKSVESLTGFPEMMDGRVKTLHPNVHGGILAIRDNAEHKQAMAEHGIEPIDLVVVNLYPFRETIAKPNVSLEEAIENIDIGGPTMVRSAAKNHAYVGIVVNPNHYDEIITMLKDQGELTKEYRFGLAKEAFAHTAAYDVAIANYMSGILNEGPTPPEYLSAYEKVTNLRYGENPHQQAAFYKEIGTAHGMGALKQLHGKELSYNNIVDMEAAWNMVWEFTNPAACIIKHTNPCGAATAATLHDAYVNAYEADSVSAFGGIVALNREVDASTAEEMSKIFLEVIMAPAFTKEALEILEAKKNIRLIELSKPESGQVTVKKVSGGLLVQTEDDLVEDRANYKVVTKVQPTEEQWKALEFAWKLVKHVKSNAILISNEKRTLGVGAGQMNRVGSAKIALEQAGEAAKGAVLASDAFFPFGDTVETAAKHGIAAIIQPGGSIRDEESIKAADEAGIAMVFTNIRHFKH
>NZ_CP019721|1045906:1051895|1047256_1048675_+|WP_077708109.1|DBSCAN-SWA
MNYDSVFDKWHEECGVFGIYDRTVDVARYVYWGLFALQHRGQESAGIAVTDGHDVELKKGMGLLTEAIKELPSLPSYMGTGHVRYSTTGSNNPRNIQPLVIHYQGGQIAVAHNGNLTNALSIRKRLEADGSIFQTTMDSEVIVNLIARSKAETQAERIADAARQIEGAFSLVITTNDSLVGVRDPQGFRPLCLGKTENGYVLSSESCAFDAIKAEFIRHIDPGEMVIIDDSGVRSTIYAEPEKIDKKLCVFEYIYFARGDSHIDGQSVYQSRLNMGRELYNETKYDADIVMSIPDSGTTAALGYARASGIPFAEGLVKNRYSGRTFIKPNQEERELAVRMKLNALPHIVGGKRIVLIDDSIVRGTTSGIIVKMLKEAGAKEIYMCISSPTIEYSCHYGIDTSVRKELIAATHTVDEIKDFIKADKLHYLSREGLCRAVSDVKPDDLCFACFNGDYSVAVPADQEEGVKYVLE

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_077708108.1|1045906_1046398_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.0e-32	47.7
WP_038149765.1|1046532_1047246_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3FCN6	Synechococcus_phage	6.3e-47	44.8
WP_077708109.1|1047256_1048675_+	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	9.9e-52	31.3
WP_077708110.1|1048661_1049723_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SQF5	Cyanophage	7.1e-63	42.0
WP_077708111.1|1049715_1050339_+	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	2.0e-20	32.1
WP_077708112.1|1050365_1051895_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	3.6e-76	53.0

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NZ_CP019721|1063084:1139493|DBSCAN-SWA
ATCAGAATATTTTAGAAATGCGTTCCACGATGTCATCTTCCATTTTAGGCGTGACGTGTGAATAGGTATCCATTGTTTCTTGAAACGAAGCATGGCCTAGGCGTTCTTGTATAGCTTTCATATTTGCCCCATTTTCAATGAGAAGTGTGGCGTGGGTATGTCTTGTACCGTGCATAGTAAAAGTTGGCTTACCGATTAAATTGGCGTATTTCTTACATAACTTACTGACTTCATCAGGGCAGCGAGGAGCACCTTTAATACCAGGAAATACTAAATTATTATTAATCCAGTTCATCGTCTTGATTCTGCGTTTATCTATGACTGTTTTATGTTTTATAAGTTCTTGGAGTGTGTCTGTATCAATGGCTATTATCCGTTTTGATGACGTAGTCTTAGTTGTATTTGATATAACTGCAGTGGATCCAATCTTGAGTGCTGTTTGTGAAATGGATATGGTCGATTTCTTAAAGTCGATATCAGACCATCTTAGGCCTAACAATTCAGAACGGCGCATACCAGTTGCAAATGCTAATTTAAAGAGTGTGTGATGCTCAGAGTTAGATATATTAGATAAGAAGCTCTTAACTTCATCTGCAGACAACGTTACCATATGGCGGACTTTAACCTGTTTTGGCCGATCTATGTTTTTCATGTAATTTTTAGGGATAATGTCATCTTTTACCGCCTGCTCTAATATGGATCCTAGAATTGTCATGGTGTAGGATATAGTCCTTGATGACAATCCATCCATTGATTCAAATACATACCGTAATGTATTAGGTTTAATTTCGGCTAACTTTACGCCGCCGATTTTATCTCTGATATAGCGATTGATAATTCCTGTATAGCTTTGATATGTGGCAGGGGTTATAGTCTTTGCTTTTAGTTGTAACCATATATTAATCCATGTATTTAATGAGATGGTAGCATCGAAATTGGCGCACGATTGGTTAGCATTTACATATTTCTCCATAGCTTCCGTAGCAGCTTTCTTAGTGCTGCCATAGAAGTATTTACGCTTACCGTTTATCATCTTTGATACTTGGTAGCGTCCATCGGTTCGTTTTTTTGCCATAAAAATAACCTCCTGAGCATAATAAATAAGCCTTAGAGGATTTATGATATAATTATATTGGAGTAAAAATGAAGTACCTCTAAGGTATGTAGTTTTTAATGGCCCTCACTGCGGTGAGGGCTTATTTTTTTACAATAAAAAAGGCCCTTAGGAAAACCTAAGAGCCTATTGTAACCTTAATGGTTACTCATCATTTGTTTGATAGCTTGGTGCTACCTCGTATTTACATACTATCATAGACTACGGTTTTTCGCAACTAAAATAAAGAAATTTTAATTTAGTTTCTAAATTATTTAACAATTCATCGGGTAAAATTATATTTGTAAGAACATCTGTGGTTCGAACCGGAGCTTTTATTCGCTGTTTGCTTATTGTTGTTATTTGTCCGATGTCAGCCATGCTTTCTGATTTTAGATTATCAAGATAGCTTAACACGGCCATAGCATCTTTATGTTGCTTTCTAAGTTTTATTACTCGTGATTGTAAAGATTTATCTGTTCTTATAACATCAATAGGATACTTTTTGGCTAAATCATCTGCTTCTTGATTAAGTGCCTTTACCATGGCCTTAGCTTTATCATCGATTAAATCCGATAATACACCTCCTAATGGCACCATGTATAAATTTTGATATGATGTATTTTTGTCCTTCTTACTTCGCAAGGGGATAACTGTGAGGGTCGATGTATTTTTACTATTTTTTATATCTAATACAATTGCATAGTGCAACCCGCCTAATTCTTGGCCTACTCTAAATCCAAAATTTACAAATACGATTTGACCCCGTTTGTATGTAATTAATTGCTTTGGCTTAAAGGTTTTTTCGTTTTTTATATAGCCGAGATAATCCCTAAGCCAATAAGCAAGAATAGCCGCTTTTTTATAATCCTTTTGCATGAGCTCCTTTACATAGTTTTTATATCTATAAAGGAGCTGCTTTTGGAATTTAATAAATTCAAGGATATTTTTGGGATCTTTAAAATTCATGTAAATTTCCTCCCTTATTAATTACATTAGAATATAGAATCTAGCGCAGTATCATGCCGGCGTTATTTTTTTATATCCCAAATATCCCTCTTAAGATGTCTCGATTACGTTCATGCTTAGCTTTCTTTTCGGCAGCTTGCTGTTCTTCAATGCGTTTTTGTTCCTGAATCTGCGCTTCATTTTCTTGCTGATTTTTATAATCTGTTAATTTAGCGTCACGACCAACTAACCCTTTTACAGAAGCAATAAGTGCTTCACCACCACTTCCAGGGGCTGGAGTGCGAGTGGCATTTACTGCAGCCTCTTTAACAACTGTATCAGAACCATTCCTATAAACATAATATTGTATGATTGTAACAGAAGAATCTGCGAAGTGAATATTGTATTCTCTTAATTCTTGAAAACCTCTAGTTTGTATCCAGACAGCCCACGCTTTAGCAGTATCAGTAGCTGGGTCATAGGAGAGTGTGTTTAAATCGACTTTCCCTGTGTAATCAGAATTTGAATAAAACCATTGCCAACGTGCGTCATTGAATTCTTTAGCACTAACCATCATTGTTACGCATAGTACAAATATTGTTACTAATACTAACCCTTTTTTCATATTGTCATCTCCCTGTGTTAAATTATGTGGTGATAGAAATCGATTCCGTTAAAGTCCCCATTTTCAATTTGAGACATCCTTACCATACGTTCGACTAAGTTAACGTGATGTTCCACATAAAAGTCATCACGAATAATATGACTTAACTCATGTTTAATTTCCTCCCTCATGCGATCATGGGGGAGATTTTTATTTATGTAGATATTATGGGTATCCACATCTTCACATTCCTCCGATACCGCATTAGTATGTGGTAAATTGCAATAAATTATATTAACTACCAATTACAACACCCTCCCTTGTGTCGACTATTTATGTTTAGATCTGTTGAGCCCGCAAAAAATCTAGTTTTTCTTTGTAAGCTTTTGACGAAGGGGCCATAAGTACGTCTTGCATAAACTCGCTAATTACTGGTATGTATTCCTTATAAATCATACTAAATACATCCTTATCAATAGCTTGTGTGAAATTAATAAATGCATTGTTCGGTAATAAATATTTAAAAACAATGAGTAATTTAAAAATATTGGTAATGTTATCTTGATATTCAAATTGAAAAGTAGTGGTAAAGTCGACAAGTAATGGCAAGCTTTCTTTTAACTTTGGGTAATCATGGTTGATAAAACTTGAAAAGTGGGCACAGTCATTACGAACTTGATTTAAAAATAATATACTTGTACGAAGTTGGCTTGGAGTCATATGGAAAAATGATGAAATATTATCCTGAATTTTAAGAACTTCATAGAAGTGTAGCATTTCACCAAATGAAAGATTATTAATAAAAATCCATATAGGGATATGTCCATGTTTTGTTCGATAGTGAGTAAACGGCTTAAATGTAGTATCCTTGTATATCTTTTTTAATCGTTTTATTAATAACTCATGCTTTAATTCATTTTTCTTTGTCTTTAGATTTTGTGTGTAATTTGATTCATTTAAATATGGTTCTATGTAGTGACAATCAATGCTATCACCATCAAATGGTCCGTAAGCTTTTGCAAACTCATAAGATATACAAGTTTTTAATCGTTGCTCGATTTGTAAAATAGGATAAAATATAAGGTTTTTAATTCTAGCATCAACTTGTTGGATACTGAATAGTTTAAAGAAATCGATATCATCAATATATTCATCATTAGTTAGAAAAGGCTTATTATATTGGTTGATAATATTGTAATATCCATATGTTTGTAGCAAATCTTTCACATACGATTTAGAATTTTTGAGTATGGTCATTCTAATATCACGATCAGAGGTTGGATGTTTAAATGGATTGTGAATATGAATTACAGCTGGACCTTTTATATCAGGGGAAGGTGATTTATTAGTATATTTAGGTAACAAACCAGAATTGGATAATATATCTATTTGTTCATCGTAAGTTTTAAATGATTTCATAATAATAAAAAGGCCATGCACACATAAGTGTACATGACCTTTTTCAGGTTGCAGCTTTTTGCAAAGCCTCCCCAGATACCATGTACACAATATACCATTGCAAGAACTCTTTGTCAAACTCCTTTCTTTTATATTGATTCTGATATTGCGGACAATTATTTATATTTAGATTTTAAAAATTCAATATATTCCACAGCTTTTTGCATATCCTCCTTTGAAATTCCACGTGATGCGGAGAATAATAAACGTGCAGAAGGACGGGTGCGAAGGTATTCAGCGTATTCAGCTGTTTCAGAATCAAGGTAGTAACCTTGTGGAGTATCATCCTTATCCCAACCGATTAACCATTCTGGATTTACTTCTAATATGGGAGCCAATCTATTAATAAAATCAATAGAAACACTAGCGATTTTACCAGATTCATATCTTTGCATATTACTTTCACTAATACCTAATCTTGCTCCTAAGTCAGCTAATGTTATGCCTTTTTGCTTTCTAATGGCTTTTATTCTTTCTCCTATTTCTTTGTTTATTGCATTTCTTTCATCGGTACTCATAATATGCCTCCAAATAAGAATCGCCCTTACAAACATATATTACAATAAACTTGAATAAAATTCAAGAAAAATTATAAAACTTTTATAAAATCTTGCATATGATGGTTGACATGTTTTTCTAATAGGCTTATCATGTAATCAGAAACTTGCATAGTGTGCAAGAAAAGTGAGGTGAAAAGATGAAATTAGAAAAACTGAAAGGATTGTTGGTAGAACATAAGAAAACATATGCAGATTTAGCAGAGTTGTTAGGCGTTTCTATTACAACTATTAACAGTAAAATGAATGGGAAAACACAGTTTGATGTAGTAGAGGCTACAATGATTAGTGATTGGCTTGGATTAGACTGCTCTAGTCGAGTAGATATTTTTTTACACAATAACTTGCATAATATACAAGTTATAAGTTAGAAGAGGTGAAATTACATGAAAAGCCCATTACAGAGACACATGGATAACCTTGGGAACAAGACGGAAGAAGGAGGAGAAACAAGTATCACAAAAAAAGAGCCACATGATGAGGCTCAAAAAAAGTGGATTATATTTAGATATTTTAATGCTTTGAAATATAACAAAGACCAATCACTAGAGGAAAAATTACAAGACATAAGATATTGCACAAGAGTTAATTTGGGACTGTTTGTGATTGCAGTGATCCTAACGATTCTAAATATTACGAGAATATAAAGGTTAATATTGCAATTATTATTGTTGTAAATATACCAATGCCAGCTAACCATGCAGCAAATTTACCATATTTAGCAGATTCCTTTGAAATACGAAGACTTTCTTCTGCAAGTTGTAATGTATGATTTTCTTTTTCCAACTGATGCAAAAAATTTAAACCAGATACAGTTAGTTGAAATTCATCAGAATCATCAAAATAATAAGGGGCAAAAAAATCTTTTGGTATAGTTACAAGTTTAAAGTAGGAATGTATTAGAGAGGTAGTATTAGAGATTGCAGATATACGTTCAATAGAATAAAAGGGTGGTTCAACTTTCTTTTTGGGAGTATTGGATAAATACAATTGGAGAGTTGCATCGTTCAATATTGATACTTCTGCTTTTAATTCAGCGTAAGTTTTTGACTTCCTATTAATGAATAATATTAATTTCTCTAAATTTTCATTGGTTAGAGAATGAGCGTGTGAATCAAAGGAATCAAGTTCTTCTTTATAGTTTAAATACTCTTGTTCAATAGAATTTTGCGATAACTGAAGATTAGAAATAGGTAATGCCTTCATAATCCCTATATTTTTTTGGATGGCATTACTAATAGCTTCAGATTTTTTAATAAGTCGCTAGTGGGTTTCATAAAAGACCTCCTTTCAGAGTAATTATAGCACTAGGGAAGGCGATACGAAGGAGAAACAAATGAAAGAAATTAAAGAAAAATTACATCAAGTAATTTTAAAAAGATTAGACATGACAATGAATGAAACAAGTTATACAGATCCATATATTGTTCCATACATTGAATTATATTAACGCTTAGAAGAAAAGAGTGTTCCACACCAAGAAGAACACTCTAAATAGTTAATTAAGAAAGGAATTATGAAATGGATACCACAGAATTGGCATTAATTATTTCAGCAATGGCATTAGGAATAGCTATAGCTAAATTAATTCTACAATAGCATAGAGTTATTTAAATATAGAAATTATGACTGCTATAAATGAAAGAAATAAAGCTAGATTAGAACGACATGTGGCATGCTTATCTATCTTACGTTGTTCTAACACTGCTTCATAATATGATCTTCCACTTGGAGTTATTTCATAAGTGTTATTAGAAAGAATACCTTCTGAATCACTATGAAAACCATCGGTATTGGTAATGAAGTTTAGTTGTAATAAGTAAGATAATTCAAGCGCCATGTTATAGGCTGATAGACCAGTAATACCGCTTAATTGTTGTGGAGACAAATTTCGCTGATAGAACTGTTCTAAATAAGAAAAACTTTTTTTATCCAAAAGATATAAGTCCATATACTCACCTCCTTTTGAGATGAGTATAGCATGAGTGATAAAAATTGAAAGAGGTGAAATCACATTTTACAAGGTAATTACGGAAAACCGTAATGCAGCGAATGTGAAAATAACAAAGGAGCGATATGCGAACCATTTATTAACACAGAAAGGAGATTGCGATGAAAATCATTATAGAAGGTACTGCTGAAGAAATTTGGGCATTAATGGAAAAAGAGCCCTGCTGTGAACAGAGCTCTAGTAATCAATGGTTTCCTGAAGACAGTAATCGGAAATATTACGAAAAATCAACAAGTGGTCCTAACCTGAAAAAATAGTTTCGTTGATATATTTCCAAGCCTCCTTTGGTAACCAACCTTGGGTATTATTTATTACTTCTATGACCAGTAACCTATCATTGCTATCTAGATATTTGGTTATTTTGTCAGATACTTCTTGGGCTGATTGATAATTAGATCTAATTAAATAGGACGATTTCCAATATGTACACCAAGCTCCATCACTTGCCGATTTGATTGCTTGGATAACATTTTCATAATCTTGTCCCGCTTTATTCAAATCATAAGTAATAAAATAACGTTTTTTCATTCCACTCACCTCCTTTCTATATCCATTATAGCAAACGCGGAGGTGAGGGAAGTAATACTAATAAACAGATGAAGGGGGTGTAGAGATGAAGAACCCTGTAGGGGGGATTTATACAAAAGAAAATGGAGAACAATTTAATTATCAAAATAAATTTATAAGAGTTGAGCCAACAGGGGGTGATTTTTGGGACTACTTTCCATTTATTGCTGTAGTGGTTTCCTCTGTTTCATTAGGCGTATCCATAGCATTTTGGGTGCTTAAAATTTTATGAAAATTAGATAAATTGTAATGGACTTTATAGAGCTTAAATTTTTTTCTATTAGATGTTGATAAAGGAGAGCGATGCCATGGTAGCCAAGCATATTGAGGAATTTTAAATTCAATGCAGATTCCCTCTTTAATAGAAATATTTTTATTAAGGATAACCAAGATAGGTAACTCTAAACAGCTGCCTGATGTAATTGGACCGCAGCGTGATTTAGGAAGATCAATAATAAAATTTTCTAAGGCCTTTGGCCCAAATGGACTAATTAATAAAGAGGGATTGTCTCTTAGCCATGGAACGCTAGATAAAGTGCAAAGAAAATGGTTTTCATTTGTTTTAGGGTTATAGGCTCGTAAATCAAAATAAGAACTATTGGTAGTGCTGGCATTCACAATGATTGCGGTTGTAAAAATTGCATATTGATTAGTTGAATTTTCAAAAACATTATCATGGGCTTCTATATTTTTTGTAACATCTAGTGCAAAGCAATTGGCATCAAAATCAACAGTTATTAATCTTCTTTCTCGCAAATATGATAGTAAAGAAAGCAATAAAGCCGCCAATGAAATGATTATTGGAATAAAATCCATAATTTCACCTACCTTCTAAGGGGATTATACAAATAATTATTTAAAAATACACAAAATATTCATGAAAACTTTATGAACACATATAAAAAGATATAAAGGAGGATTATTGTGGACAGGAATAAATTATGCATTACAGTTGCTGAGGCTGCTGAACTAGCAAGCGTTCCTCAGGATGTGATTCGCCAATGGGCGGCCGATTTTGATTTCCCGTCGATGAAAATAGGAGCCCGAGGTGGCAAACGATTGATTCATTTAGATTCGTTTAATGCATGGCTAGGGAAACGATGCCAGGCACGAATAGGAGAGTAAGGAGGTAAAAGACAAGATGAGTGCGATGACATACAAAGAAAAACGTGAGTTTAGACGTGCTGCTATGGCGCCACAATTAGCTGATGTTATAGAGGGTTTTATTGTCGGAGCATGTTTTTTATATCTAGTAGTAGGTATTTTCTATTGGTGGATTACAGGGGAGATATTAGTGAAATGGTAAAACGATGTTATCACTGGGGATATAAATTCTCCGGATGTTAGAAAGGATTAAGGAGGGGATAAAAAATGAAAGATAAAAGAGAAAAGGCACTAGATCTACTAAAAAGATATTTAATGTTTGATGATGAAGAAATGCAAGTTTTAAGGGAACACATTACATCAATCAGCGTAAGCAATAAAAGTGCAAGTTTAGACTTTACTATTCTTGCTAATGGATGCGCTATTTTTGTTAAGCGAAAGACAGGGGAATATGTATTACGCATAACAGGTAAAGGCCCAATTAAAGAAAACAAAGTATATCTTGCATTAAGGGCAAGAGAAATACTGCTTGATGCGGTGATGAATAATGAGTAAACACTGCAGCATATGTGATGAGTGCAACAAAAAAGGCCATGCCTACATTCATTGTAGACAGGCCAAAGGAATAATCTGCATGGAACATTGCGATACATGTCAATATTTAGAAATAGAAAAAGGAGATATGCATTGTAACTATCCAAGGCAAAAAGAAAAGGCCACTAATTAAAGTAGCCTAATCAAGCACGTAATTACGTACCAAACCTAACGTAATTATATCACACATGGGCATAAAAGACTAGGGAAAAGCTTATTTAAAGGCTTTTCCTTATTAACTGGATATAAGTATTAAAAAATCAACCATGGGGTAATTACGAGATGAGGAAGCGTAAAAAAGTCATATCTAAAAACATGATAGAAGTACTTGATTATCACACATCAAGAACATATAGAAAGAATGGCAAGCGTGTAAAAAAGAAAAACATCACACCAGAAGCACAGAAAAAGCAAAATGAAAAACAAGCGGAAGCAATGCTGCGTATGTTGATTGATAATAACTTCACTACAAATGATTGTTATATCACACTCACATATAAGGAACAGCCAGCCACATGGGAAGATGCAAAGAAAGACATTCAGAATTTTATAAGAAGGCTAAAACGCAAATATAAAAAACTGGGTAAAGAATTGAAATACATTTACATAGCGGAGGGAAAAACAAGAATACATTTCCACATGATCATCAATAATGCAGAACTATATTCAGATGAGTTGAATGAACTTTGGCCACATGGCATGCATAAGTTGATGTTGTATCAAGGAAGAGCAGAAGATGCAGTAAAATTAGCAAGCTACTTTGTGAAAGAAAAACGGAGTGCATGTTATTCAGATAAAGAAGATGCATTTAAGCGTAGGTGGAACAGTAGCAAGAATTTAGAAAAACCAAAAGTAAAAACAGAAATATTGAAGCCAAGCGAATGGAGAGATTATATCCAACCGCCAAAAGGCTATTACGTAGAGACGGACAGTGTAGTTGAGTCTGTATCAGAAGAGGGATATCCTTACAGATTTTATAGACTAATAAGAATTGAGGAGGTCAAACATGGCACTACTAGGAATAGGCATTGTAGTAGGGGTAATACTAGGAGTATCAATAATAGCATTATGCGTAATTAGTAAAGAATGTGAGGAATGGGAGGAAAAAGTAAATGATAAACGTAAATGAGGTATTTTTAAGTGGCAACGTAGTAGCAGATGCAGAACTACGTTATACAAAAACAGGAAAGCCAGTACTCACATTTAGAATGGCAACCAATAAATATGTGAATGAGCAACAGAGTACACAATATCACAACATTGTATGTTGGGTTGATGCGGAACTTTATAGTGGGTTACGTAAAGGTGATTTTGTAGCCGTGAATGGCGAGTTAAGAACTAGATCATATGACAAAGACGGAAGCAAACGATATATCACAGAGATTATAGTGAAAAATCTTACATACGGCCTTAAACAAAATGAAAGCGCTGCAAGTAACTTTGATAATGGGTTTGCAGACAATGATGAAAATATCCCATTCTAGGAGGAAATAAAAATGAGAAGAGGTAGACCAAGAAAGATATGCAGTCATTCATTTGGACCAGCTAAGAGCGGTGCATTATGGGTAAAAACATCTTGCCCTAAAGGGAAAACATCAATTAAAGTCTTTAGAGGCAAAACAGCAGGCACATTATATTGGCTAAAAAAAGAGGAATGTGAAGATTGCCCTGCATATAGTCCGACAAAGATTTATGCAAAATAGGAGGGAATATGCAAAACACAAGCATGGCAGGTGTACCGATTAATTGAATAAACTGGTTAGCACTAGGTGCAGTAGTGTACGGTGCAATGGAAAAGAAAAAAGCACTAAGAGTCTTAGGATTAAAAGAGCAATATAAAACAAATGATTTAATCAAGTATGCAGAAGTAAAAGCATTAGTTAATAAAGGGATAAGTTACAGAGAAATAGCAGAAGAGTTAGGGGTAGGCTTATCAACATTTAAAAATAAATGTAAAGAACTAGGAATAACATCTAAAAGGGGTAGAAAAAGTAACAAACATTGATGCGGTTGCGCTAGGGGGCAGACTATGAACCATGTAACAACACTATTCAATAGTAATGAGTTTGGGGAACTTAGAACCATCATTATTGAAAATGAAGTATACTTTGTGGCCAAGAGCGTAGCAACTGCACTTGGATATAAAGATACTGCAGATGCAATAAGAAAACATATTGATGAAGAGGATAAGCTGCGTTGGCAAATTGCCGACACAGGCCAGAAGAGGGAAACATATTTAATCAATGAGTCTGGACTATATTCCTTGATATTGAAATCAAAGATGCCAAGCGCTAAGAAATTTAAACGCTGGGTAACTAGCGAAGTACTTCCACAAATTAGAAAAACAGGTAGCTATGAGTTAAATATTCCAAAGACACTACCAGAAGCATTGAGATTGTATGCAGATGAAGTAGAAGCACACAACCAATCAAAGGCAATCATTGAACAACAGAAGCAACAAATAGCCGAATATGAGCCAAAGGTTGATTATGTGGATAAAATTTTAAGCAGTACAAACGCGATGACAGTAACACAGATTGCTGCAGATTATGGACTAAGTGCGAAAGCATTAAACAAGATATTACATGATGCACACATTCAACGTAGTGTAAATGGACAATGGATTTTGTATAGCGATTTAATGCGAAAAGGATATACAAAGACTAAAACACACACATACATGACTACAGATGGAAGATTGGAGTGCAAAACATCTACACGTTGGACACAAAAAGGAAGATTGATGATACACGAGTTATTAAAGAAGTTAGGAATCAATGCAGTGTGTGAGGAGGTAGCATGAAGCCATTAATATATAAAGGCCTAAGAAAGAACTTAAACAGGTCAGAATGGGTAATCAGTGATGAAATAAAGCAAAGCTATTCACAAATCAGACTACTAGCAATAGAAAATGATACATATGCATGGGTACAAATTGAGGACGGAACACTATGCAGAGGAAGCGAAGCAAAAGACACGCTAGGGAAAAGGATATATGAAAAGGACCATATAGAGTTTGATTGCAAATCAATACAAGAAAAACCAATGGTAGGGGAAGTATATTACAGCGTTGATAAATACCAATGGAGATGTAAGGCAATTAACCAGCAAAACAAACAAAATGATGCGGTACTAGATTTTGACTTAGCATTTGTAGTGAATAATGGAAATGCAAGAGTAGTTGGTAATAGATTAGAGGGATATGAGCATGAATGATAGATACAGAAATGTATGCAAAAAGCATGATCTAATTGTAGCGGAGATATAAGATATGACGGAAGAAGAAATACAAAAGAAGTTAGGAAAGCATTTATTTTTAAAGAATATAACTATTCCTAATATAACAATGCATGGAGATGGGAAAGGGGAATATGAAGCAGATTTAATCTACTTCAATCTTAAAGCTAGAGTGGTTACTGAAATAGAAATCAAGGTAAGCATTCAAGATTTTAGAGCAGATTTTAAGAAGAAAAGATACCATGATCATTTACATGTAGGCTATTTGTATTATGCAGTCCCACAAGACTTGTATGAAGACCATAAGGATGAAATAGAAAGTTTATTAGGTGATGCGGGATTAATAGTGGCCAATATATCTAATAATAAAAAAGAAGATGTTAGATACATTAAAAGGGCAAAAAAACGCAAAGATGTAAAGGCATTAAATGAAAGTGAAGTTATTAACTATTTAAGGATTGGATGCATGAAATGGGTAAATAGATAGTAATTAGGGGATATTTAATTTTGATAAAGGCGTTATTATGAAAATACCATGTAGGGACTGCAAATTTAGAGAAGTAGGATGTCACAGTAAATGTGAAAGCTATAAACAATATAGAGCATCATTAGATAAGCTTAATGAAGAAAAGAATATGCAAGGAGATGCCTATAAATATGTTGGAGATAACGTAAGGGCAATTAGGCATAGAATGCGAAAGCTTAAAGGATATAGCTGCACTGTGAGTGATTAAAATGAAATTAGATTTATGGGTAAAGCTAAATATAACAATGGTTGATGATAGCAAGGTAAGTGGCTGGACACAGATTTATGGGAAACATGGGTTAGCTATGTACAATAAACCATTTAAAACATTAAAGCCAATTGTTAATGATCACATAGATAAAATGAATTGGTTAGCTATTTGTAATAGGTGGGGTGAAACAAATCAAATCATAGAAGTAAACACAAGCAAGATAAAGAAATATGTTATCAAAGAGTGTGTACAACCATATGATACAGAAGAAGAATATTATGCAATTAAAGAATGGTATAGAAACAATATGAGAAGAAGAACATTATTAGAAAACAATGGATAATAAAAATATTTTAGATGCATGCTGCGGTTCAAGAATGTTCTGGTTTAACAAAAAAAATAAAAATACTGTTTATATGGATAATAGGACGGAAGAAACAATGCTTTGTGACGGTAGGAAATTAATTGTTAAGCCAGATATAATGGCAGATTTTAGAGAAATGCCATATAAAGAAGAAACATTTCACCTTGTTATATTTGATCCACCACATTTATTAAGAGCTGGTGATGAGTCATATTTGAAATTGAAGTATGGACGATTAGGGGAAGCCTGGAAAGAAGATATAAAGAAAGGGCTAGCGGAATGTTGGAGAGTACTTAAAACGAATGGAACAATGATATTCAAATGGAATGAAGAGCAAATAACATTACCACAGGTAAAAAAACTATTACCATGCGAGCCAATTATTGGGCAACGAAGAGGGAAAACAATATGGTTAGTGTTTTTCAAATAATAAGGAGAAGCAATTCTTAGAAATATTCAAAGAAGTTTATAAGAAAGGAAAGTAAAAATGGAAATACTAAGTGTTGCATTTGGAGAAAAAAAGAAAATTAAATATGAAAAAGCAAATAGTACTGGGGTTACTGAAACATATCAACTAATTACAAAGGATGAATTTAGGCCAGAGATATTAGATGCATATGTAAAGGCAAGGATTGTAGTAATTGATACATTTAAGGCTTTCAAATTTATTAGAGAAGAATGGTTAAAGATTAAATCAATTAACTTTAGGTGGCATAAAGAACTGCCAAGAGTAATTGTAGCAGCAAGATATGTACTAGAAATTACAAATAAAAAAGGTGATAAATGCACAATAAGTACTTCATGGCTACCAATAGCAGAGGAAACACAAGAGAAGTTAATTCCATTGGTAGAAGAAATTGAAATGTTTGTACGTGGAACAAGAGCGCAGGGGAAATTATGGGAAGAAGAATTAGAAGATGATGCGGTTGAAGGAGAAACATTTCATATTAATGATCTAGTACAAGAAGGAGAAGCGGATGATTAAAGACCAATTAATTTATGTAGCGCATCCATTTGGAGGCAATAAAGAAAATAAATTTTCCATAGATACAATTATGAAAAATCTAGTAATGCTAGATAAGAACAATACATACTTATCGCCTCTTCATAATTTTAGTATGGTGTACTTTGAGGATGAGTATGCAAAAGGTTTGAAGATATGTTTGGATATGTTAAATAGATGTGATGCATTGGTATTATGTGGTGACTGGGAAACATCAAAAGGATGCATTGGAGAATGGTCCTTTGCAATAGCTAAAGGAATGCCAGTATATACATGGGAAGAATGGACCGATAAATTAAAAGAACAGGGGAACCAGTATAGATGACAGGAAGAGAATATTTAAATCAGATAAGAGATACTGATTTGAATATTAAATGTAAGGAAAGAGAAGTATTTAGGTTACGGCAAGATATACTTTGTTTACAAGCCATAGATTATAGTAAGGATATTGTAAGCGGAGGAAAACCAATAACTATTGCGGATAAAATTGCAAATCTTGATGCGGTTACAGAAGAGATTATGAAAGAATGGAGTGATTTCTTACAGGAGAGAGAGCGAGCAAGATTTATGATCAATCAAATTTGTAGTACTAAGCAAAGGATTGTATTAGTAGATAGGTACATTAATGGATGTACATGGGAAAAGGTTGCAGAACTAATAGATTGTTCAAGGCAGAATGTTCATAACTTACATAAAAGAGCAATTAAAAATTTTGAGGAAATTTACAAAAAGGTTGCTATTATTTGACACTCAATATATGAGATACTGTATGTGGGCATGGATGAAGAGAACACTTTCAACAAGCCTACTAGAATATCCACATACTATTAAGGACTACATCATACAAAGGTCACACAACACAGTATGATGCGGTCCTTTTTAGTTTATAAGGAGAATTTGATGAAACACAAAAGAATTACATCAAAGAAAACAATTCAAGAAATACGGAAGCAATATTGTGAGATATGCGGACAACGTACAAATATTGAACCGCATCATATTAATACACGTGGTAGTGGTGGCGGAGATATTAAGGAGAACTTAATACAACTATGCACGCAATGCCATATCAATACACACAGTGGGCAATATCCAACAAAAGACGATTGCTTAAATAAAGTAGCAGAGCGTGAAGGTATTACATATTATGAAGCATATGCAATTAATCGTAGAGCAATGGGATATGATGTATGACAAGAATAAATTGTAATAGGGGCAGATGCTTAAATAATAAATATGGCATCTGCACTGCAGATACAATTGAATATGAGGGAATATGTCAAACCTATATAACACACGACCAAGCACACAAAAGTAATTGTGGATTATGAACTCGTTCTCATGGCAGATTTAAGAGAAACAGCCGTGATGTATTAAGATAGCTTGGGTGTAGTGTCCGTACTAAATAATAAAAAATAAATTTAAATTATTACACGATTTGTTGAGTTTTTGAGTAAATCTTTTGTGGGTCCTTCTGGAGAAAAATGAAACCGTGCGGTGGCCGAGACCCCAAAATTTGCCTAGATTTTAATTTTTTTATGGCCTTGCTAGTGATACAGGTAATGAAAGGAGGCTGATTGATAAGTGAAAATTACAGATGATTTGAAAACAGCAACGGCCTCTCAGTCGAACTTGGCAAAAGCACTTGGGCTCTCGCGTCAACGTGTTTCGCAACTGCTCCAAGAAGGAGTTTTAGCAACGGATGAAAAGAACCAAATTCTGGTTATCAAATCCGTTATCAATTATGTCAAATATAAGGGCCAATCTTCTGCTGAAGAGGAAAGCAGTTCCGATGATGCGATATTCGAGGTTGAAAAGGCCAAGAATGAACGTGCGAAACGCAAGATTGCTGAGTTGAAGCTAGCCAAAATGAACGGCGAAGTGTACTCAGCAGATACTGTAGAACAGGTAATGACAGAAATGCTCGTGAATTTGCGTACACAATTGTTAGGATTGCCAACTAAATTGGCGCCACAATTACAGAACGTAACAAAAGAGGAAGCATATAACTTGTTAACTCAAGAAATTGAGGATAAATTATCTGAATTAAGTGAATATACGCCGTCATTATTCATGGATAGCGATGAATTAGACGATGATAAAGCGCCAAATTAGGTGCTTTTTAATGCAAAAAAAGGAGGTGATAGCATGAAAACGGCAAAAGAATTGTGGCAATATGCCTCTAAAATGGGCTTAAAACCACTACCAAAAACCAGTGTTAGCCAATGGGCTGATGATTATCGCATGCTATCACAAGGTATTTCTGCGGAACCAGGGCGATGGAAAACAAGTAGAGCTCCATATCAAAAGGATATTATGGATGCATTTACGCAACCTGGTATCAATCGGGTAGTGGTTAAAAGTGCCAGTCAAGTGGGAAAATCAGATATCATGAATAATGTACTAGGGCGATACGCTCATCTTGACCCATGTGCAGTCATGATGATTCAACCTACTATCGAATTGGCTCAAGATTATTCGAAGTCTCGTATTTCTCCGATGATTCGTGATACGAAAGTATTATCACAAGTGTTTTACGAAACAAAATCGGAAGACGGAGCTAAGACACGAGACGGCAAGAACACAATCTTATCTAAACTCTTCCCTGGTGGTCGTCTCATCATGTGTGGTGCGAACAGTCCGGCCGGATTGGCATCACGTCCTGTGCGCGTACTACTTGCGGATGAAGTAGACCGTTTCCCAGATAGCGCCGGCACAGAAGGTGACCCTGTAGACCTTGCTGCCAAACGTATGACAACGTTCTGGAATAGGGTAATGGGGTTATTCTCCACGCCAACTAATGAAGGGAGCTCCCGCATCGATGTAGAGTATCAAACAGGTACGCAAGAAGAGTGGCAACATGAGTGTCCTAATTGTGGTGAGTATCATTTGATACGACATACTGAGATGGAATGTGAGACAAAGGAACATAAGGACGCTAAAGGCCGGAAGATTATAGTAGTTAGTGATGTGAAATGGCGGTGTCCAGATTGCGGATCTACATTCTCTGAAGACGAAATGCGGAAAGTCCCTCAAAAGTACATATCGAAAAACCCAGCTGCGTTGCATAATGGCATACGCAGTTTTTTTGTGAATGGATTCACGTCTCCGTGGCTCACATGGAATGACATAATGAGGGAATGGCTAGAGGCAAAAGGCGACCCTACACGTGAAAAAGTAGTTATGAATACTCGTTTTGGTGAATCATATGCGCAACAAGGTGCATTCGAAGACTACCAACAATTCATTAGGCGCCGTGAGAAGTACGGCGCAGACCTTCCGGACGGTGTGTTACTGCTAACTGGTGCCGTCGATACACAAGACAACCGGTTAGAGTATGAAATCACCGGTTGGGGGTACGGTGAAGAATGTTGGGGAATCTGTAAGGGTGTTATCTTAGGAGAACCTGATAATAAAGCGACATGGGATGCACTTGATGCGGTGCTTGATAAGGTGTACCGATTTAAGAACGGAACAGGGCTTAAAGTAGCACGTGCTTTCATTGACTCCGGCGGTCACTACACGTCAAAAGTATATGAATACTGTGAAAAGAACTTCAGCAAGCAACGATTTGCCATCAAAGGTACGGCCGGAACACCTGGCATACCGTTAAATTATAAGATTGGTAAAGCATCTGGAAGCAAGATTCCACTTGTCATGCTAGGTGTAGACGATGGGAAACAACAGGTAATGAGCCGATTGGCCATCGATGAACCTGGCGCTAAGTACTTTCATTTCCCTTTGGATGAAGAATTCCTAGGAACTAGAGGGTATGACGAGTTGTATTTCAAAGGGATCATTTCGGAACACAAGAAGAAAGTAAAACGTAAGGGCGTTATCCATGAAATATGGGAACCTACTGCAGGGGTTCGTAATGAACCATTGGACTTACGAGTCTATAACCTAGCATGTATGAACTCAATCCACCCCGATTGGGATAGATTGGCGGAAGTAGTTAAAGGTGGAGGCTATTCCGCTACAACAGTAACTGCTCCACGGAAGAAACCAATGCGGAATCGTGTTCGTAGAGCTAGTAAAGCGGCAGATATTTAGGAGGATGTATGGCAACTAGTTATTCAAGAAAGCCAAGGCTAATTGACGTGCGATTAGAATGGTACGTCAAAGCTGAGGAGGCAATATTGACCGGGCAAAGCTATACAATCGGAAATCGTACTCTTACAAGGGCAAATTTGGCTGAAGTAAGAAAAATGATTGATGATTTAGTGGCAAGAGGCGCCAAATTACCCGGTATGGATACCGATAATGGTCGTGGAAACAGGTCGAAACGGGTAGTTTTTAGAGATTAGGAGGCTAAAATGGCGAGAAAAAACAATAAGTTTAGCGCTAAAATAGGCACTCCGAGGGCTAAAAATAGCGGATATAGTGAGGGCGGAGCTTCTCACAATAACAAATCATTGAAGGGATATAACCCTAGAAAATTGGGCTATAAGGCGGATATTGGTGCGAATTTATCGACTTTGCGTGATAGATCCGCAGATTTAGCTATCAATACACCAGTTGGCACGGCTGCAATCAACACAAGCACTACTCATACAGTTGGCGCAGGCCTCAACGTGTTCCCTAGACCTAAGTTTCAAATCTTGGGAATCAGTGCAGAGGAGGCTAGAGCATGGGCTCGTAAGGTTCGTGCTGAGTTTGATTTATGGGCCGAATCAAAAGACTGTGATATCTACCGTAAAAACAATTTATATGACATGCAAAGCATAGCATATCAAGGATATCTCACAGATGGTGATAGTTTTGCGGTATTTAGACGTAAGCCGACAACACCAGATATGCCGTATACGTTGCGCCTTCAATTAATTGAAGGTAATCGTGTAAGTAATCCGCTTACTGATTCCACATATGTTACAGGCGACCCAACTGGCGTTGAAGCGCTTAACCCAGATAATGGGAACCGCATATTGAATGGTGTAGAAATCGATACTGACGGTGCTATTGTAGCCTACTGGGTATCTAATCAAGTACCTGGCGAACCAATTACAAGCATGTTAACGACATGGGCAAGGGTTGAAGCATACGGCAAGCGTACAAGCATTCCGAATGTACTGCAAATTAGTAATGATACTAGACCAGAGCAGTATAGAGGAGTTCCTTATTTGGCTCCAGTTATTGAAACGCTAAAGCAAGTGTATCGATATACAAATGCAGAGCTTACATCGGCTATTATTAAATCGTATTTTGCGTTATTCTTTACGGAAGCCGTGACTAATTCAGGTTCATTAAATGATATGTTGGCCGATAATGGTGTTGATGATCCAACGGAACCAGTAGTCGATGTATCAGAATACAATTTAGGACCTGGCACATTAAATGCCTTACCTAAAGGTGTGGATGTAAAAAGTGTTGATGCTTCCAATGCTCAATCTACTTTTGAAGTATTTAGTACCCAACTCATCAAACAAGTAGGTGCTGCACTTAACCAGCCTTACGAAGTATTGATGAAGAACTTTAACTCTTCGTATTCTGCAAGCCGTGCAGCAATGTTACAGGCTTGGGAAGAATATAAACTACGGCGAAAGTGGTTCGCTCGTGACTTCTGCCAACCAATCTATGAGATATGGTTAATGGAAGCAGTAGCGAACGGCCGAATTGAAGCGCCTGGTTTCTTTGATGATCCATTAATTCGAAAAGCATGGTGCAATGCCGATTGGTTCGGACCAACGATGTCCATCCTTGACCCTGTTAAGGATATGAATGGTAGTACCCTTCGCATTGAGAATGGAGTTTCCACTCGCGAACGTGAAGCGGCTGAAATGACAGGGACAGACCTTGAAGAAAACATTGCACAACTTGCATTTGAAAAGCAACTCATGGAGAAATATGGCATGGAGCTAGCTGATGCGGTAAATCCTTCCGTTGGCTCTAAATCTGAAGCGAAAGGAGGTGAAGAGGATGAATAAATTTTGGTCTGTTAAGAATTTTGTAAATCAAGATGGTACCGGTCAATCTGAATTGTTTTTGTATGGTGATATTTCTGATACCTCTTGGTGGGGTGATGAAATTACACCACGTGAATTTGCAAGTGATTTGGCTAGTTGTAATGGTAATGACTTAACAATGCGCATCAACTCTGGTGGTGGTGACGTGTTCGCAGCACAAGCTATCCACAATATGATCAAAGCCTATACTGGCAAAGTAACAGCACATATTGATGGCTTATGCGCAAGTGCTGCTACAATTATTGCCTGTGCGGCGGATAAGGTAATCATGCCAAGTAATGCTCTGTACATGATTCACAATCCATCTGTATTTCTAGGTGATAGCTTTGATGCGGACGGATTAACTAAAATGGCTAACTATTTGGCGAGTGTTAAACAGACAATCGCAAACATTTATTTGAGCCGTAGCGACGTTTTGACATCTGAACAGGTAAATACACTTATGGATGATGAAACGTGGCTCACGGCGGACGAGGCGAAGTCCTACGGCCTGATTGATGAAGTAGATACGGCGATTACGGACAAAGCTGTTATGAATAACGGAATGGTTATCGTAAACAAAGTATCTTGCAAATACTCGGCCAAAAATGAAGCCAAAATCAAACAATTTTTAACAAGTAAGGAGAAACCTATGACTGAAAACCAATTCATGGCAAGCTTAAAAGGTTTGCTCGGTATTTCTACAAATGAACCTGCAGAAAACGCAGCAGTAACAGCAGAACGCGAACGCGTTGAAGCATTAAATACGTTAAAAGGTGATAATGAAGTCGTCAATCGTTTAGTTGATGTAGCTGTTAAAGAAGGTAAAACAGTAAATGAAGTAACACCTTTCATCTCTGCCGTATCTGATATTCCTGCAAGTGATAACAAAGTAGTTGACCAAATTCGACAATTAGTTATTGATCAAATGGAATCTGGTGCGGATAAAGTGGCACCTCAAGGTGCATCTACAACAGAAACCAACGATGCGGTAGCAAAAGCTAGTGCAATTGATGAAGTCGTAGCATTTGCGAATGCTAAGAAAGGCGGTAAATAATGGCATATTTCGAGCAAGTAAATGGTGTCGCAGCTGATTATCTATTAGGTGGTGGCGGTGTACCGGTATTAACTCAAAATGTAAAAGTAGCAGCCGGCGATTATAAACGTGGCCAAGTTCTTGAAAACAACTCTGGTACATTCCAAAAAATCGCAAGTGGTAAGCCTGCGGGTATCGTAGTATCTGATACTACTGCAACTACTGAACACAATGTATTAACTGTATACATTTCCGGTCGCTTTAATCGTGAAGTATTGGTAGTTGACCAAGCTTACAAAATTAATGATCATGAAGCGGACTTCAAGGACGCTCACTTATTCTTAACTAGCATTAAATAGGGGGAACTATATAATGGCAATTGATTTCAAAGATACATTTTCCTTGATGCAAGCTGTGGAACGAATGAAAACTCCGGCAAGTTTCTTGCTTGATACTTTCTTCCCACAAGTTCCAGCAGTTGCAACTTCTAAAAAAATCGCAGTAGAAACTCGTAAACGTGGTCGCACATTAGCACCTTTCGTATCTCGTGGTGCATCTGGCGTTAATGTTAAACGTGCAGGATCTAAAATTGCTTTATACGAAGCACCTATGATGGGCCCTCGTACAGTTATTGACCCAGAACAACTTGATCAACGTGCATTTGCTGAAAACATTGTGTCTACAATGACACCTGCACAACGTGCCGCACAAATGCAAGCTGAAGATTTGTCTTACTTACAAGGCACAATTATTAATCGTAAAAATAAAATGGCAGCCGATTTGCTTACTACTGGTAAATGCAAAATCGAAGGCTATGCTGACGATGGTGAAACAGTTCAAGTTGATGAAATTGATTTCGAATTTGAACAAGACATTACACCTACTACTACTTGGGACCAAGCGGGTGCTGACATTTATGGCGACTTGAAAATGGCGTCCGAAAAAATTCAAGAAAACGCAGGTATCGTTCCAACTGTGTTAGTCGTTGGTAAAAACGTTGAAAAATACATTCTTGATAATGCATCCATCAACAAAATGTTAGCAATTCCTAATCGCGAAAACATGTCTATGTTCAGTTTTGCTCCTGAATACTTGTCTCCACAAGTTCGATATGTTGGCCGTATCATGTCTTTGAATATTGATGTGTACGCATACCTTGAAACATATCAAGATGATGAAGGTAAAGTAAAATCCTTTATTGGTGATGATGCAGCAGTATTAGGTGTTCCTGGCCGTGGCCGTCAACAACATGCAGCAGTAACATTGCTCAACGATGACAATCAATTCACAACATATGCAGGCATTTATGTACCTTACTACTATGCTAATAAGGCTACACAAGAATTAACATTGTCTGTATACTCCCGTTGCGTATTGATTCCTGAAACTATCGACGATTGGGCTACTATTAAGACTAAATAGGGGGTAACCTACTTATGAAAATCAGAGTATTAAAGGGTTATTTAGCACATGAAGGCGAGATGTATGGCAAAGGCGAAGTAGTCGACATCAAAAAGGAAACGGTTGCGTTGTCCTTGCTTGAATCTGATAAGTTTGAATCTGCTGAAGATGATCCTATCGAAGTAACGGAACCATTGGAAGTCGTTCCAGATGAACCAGAAGAAGAAATGGAATTACCTGAAGTTGATGCGGAAGTTACGGTGAAAAAATAATGCGATTTAGAGATTACCTAGAAAGCGATATTGACGATGTATTCCTTAATGAAGACGAATTCGCCGAAGGGCATAATCTAAATGGCACAGTAGCTAAAGCGATTATCCAATCGCCAACGGCGAGGGAGTCATTCTTGTCGAATGGCTCTCACGTATCAAATGACGGATTACACGGGGTGTCTGTATTTGTGCATTGCAAATTAAAGGACATCCCTGAAATTCCATCACAGGGAAACGTATTCCGATTAGATGATGATGTGTACATCGTTCAAAGTGCAACGGAAGAAGATGGGCTCGTGTCTATCGAACTTAGAGCAGAAGCTAGAGGCGGTGTTGACGGATGGTTGAGCTAGAACTTGATAAAAGTGCAGTGAAAACAATTGAAAAAGCACTGGAAACATTAAAAGAAGATAGAGTTCGACGTGTCTGCCAAGCCGCATCTAAGCGTGCTGCAACAACCGCAAGAAAAGCAGGTACGCAAGCACTACGTAATATCTACGCCATTAAAGGTGTATCGGTCGTAAAGTCTGGTGTATCTATTAATAAATTGAATGATGGCACAGAAATGCGTGTCAAAGGTGGTTATACTAGCGCTCAAAAGTACTTTAAGATTAAATCGCTTAAACGAAAAGGTGTGTTTGTGTCTATTAAAAAAGGTACAGAAACAAAGGTACCAAATGGCTTTGTTAGTGCATCTGGTATATTCATGAAACGCCAAGGCAAGGACCGATACCCATTAAAAGGGATATATGGACCAGCCTTACCGCAAATGTTTGGTAATGAAACTGTTATGAATGCCATGCAAAAAGAAGGCATGGAAATGTATGAAAAGCGCCTATATCACGAATTAGAGCGTGCGTTAGGAGGTAACTAATGACACCATTAGATGTATCAGACGGCATTGCCGCCTATCTCATGGATGAGTTGCGCAAGCTAAATGAAACAAGTGATGTTACCACGAGCCCTATTCGAGTATGGAGCGGGTTCTTACCAAGGGTGGATAAGAATGAAGATAAGCGCAAGTTATGTCCAGCGGTAGTAGTGCATCCGTATTCTGTTAGTGATGCGGATAGTTCGACGGTAGGTATTACTGTATTGGTAACTACTTATGACGAGGCCTTAACAAAAGGTCATGTCGGACTATATCACCTCTTAGAGGTAGTGCGTGAGCGGTTACTATCTGATAATCCAGTAGCGCTTAAATATGAAATTAAGGAGAATACCGTTAATACAACAATTCCTGATGATCAACCATACCCTCAATGGGTTGGATATCTTGAATTTGAAGTGTACATTCCAGTTATTCGTAGAAATCTTAACAAGATATTTACGGATAATAAAGTAATTGAATAGGAGACAACGATGAACCCTGTTGTATATGTTGGGCCTTCGTTCCGCAGTAGCCGGTTAAATCAATTCATGGTATTTAGCGACGGTGCACCACTGCCGGAAGCGGAAGACCCTATTTTTATGCATTTATTCGTGCCTCTGGACGAACTCAACCAAGCAATGATTGATGTGAGAACACAAGGCACACAATTAAATGTATTCTATGTTAACGCATTGAAGAATTATAAAGGAGTGAAGTAAATGGCCTTTTATCATGGCGTCAAAACAAGTGAGCAAGCTACCTCTGTAATTGCTCCTGTCCAAACTACTGCCGGCCTTCCAATTGTGTTCGGTACTGCACCTGTACACCTTACAGAAGACCCTAGCGCAGTAATTAATAAGCCAATCATCTGTTATAGCTGGGAAGAAGCTGTTCAACAACTTGGCTATTCTGAAGATTGGACACATTTCACATTGTGTGAAGCAATGTACGCACAATTCAAATTGTATGGCGTAGCTCCAATCGTATTTGTTAACGTATTGGATCCTGCTAAACATAAGAAATCCACTACAACAACTGCTACATTGACAGAAAAGAAATGCATTGTAAAAGCTGCAGTATTGCTTAACACATTGCAAGTATCTAGTGGCGGTCAAACAGGTGTGGCCAACACAGATTACACGGCGGCATTTGATGACAAAAATCAATTAATCATCTCTGTTATCAAAGGTGGTAAGTTCGATTCCGCAAGTACATTGGACCTCACATACGATGAACTCGATGTAGAAAACTTCGATTATAAAAACGTAATCGGCGGTGTAGATAGTAATGAAAAAGCAACAGGCTTTGAATTGATTGATACAATCTATCATCATTTCGGTATTGTACCTGGTCTTATTGCTGCACCTGGATTCTCTCAACATCCTACAGTCGCTTCCGTGATGAAAGCAAAATCTCGTGTTATTAATAACTTGTTTGGTGCGACTACTTTGGTAGATATCGATACTACACAAGTTGTTAAATACACAGATGCTTACGAATGGAAGAAAGGTAATAGCTATACAGGTGAATCTGAAGTCGTATGTTGGCCGATGGTTCGCAATGGCGATTATATGTTCCATATGTCTACGCACATCATGGGCATTATTGGCAAATGTGATGCATCCAATAGCGATATTCCTACGTTATCCCCTTCCAATAAGTCTATGAATATCACAGGCTTGTGCTTAGCTAATGGTAAGGAAGTAATGCTTACGCATTCGCAAGCAAACTTATTGAACTCTCAAGGTATTATGACGGCCGTTAATATCAATGGTTGGGTATCTTGGGGTAACTATACAGGTGCATATCCTGGCACAACTGATGTTAAGGATACATTCATTTGTGTACGCCGGTTCAATGATTGGGATGACCAAACATTCATCTTAACCTATTGGCAAAAAGTGGATATGCCTATCTTGCCTCGTAATATAAAGACAATTCTTGATAGTGAAACAATCCGTCTTAACGGTCTTACTTCTCGTGGCTTTATCTTGGGCGGTCGTATTGAATTCAAAGAAGCAGAAAACCCTACAACAGATTTGTTGAATGGTATTATTCGCTTCCATAAATACCGTACACCTCCAATTCCAGCGCAAGAAATTGAAAGCATTTCTGAATACGATGTTTCCTATTTCAAAACGCTATTTCAAACAGTATAGAAAGGGGTAATTAATCATGGCATCTATCAATCAAGTGCCGGAAGTACTTAATGACTTCCGTGTATACGAAGAAGGCTCTGACAACTGTTTAGGTGTTGCCAAAGTGGAATTACCTAGTGAATCTGTAATGACTCAAACTGTAAAAGGTGTGGGCATTGCAGGTGAAGTAGAAGCGCCAGTTATTGGACACTACTCCTCTATGGAAACAAAACTTACTTGGAACACTCCAACAGAAACTACACACCGCCTTACGGGTGGTCGTGGCGTACGCTTAGAAGTACGTGGTGCTATCCAATGTTGGGATAGTGGCAAAGATAAATATGTAATCGTGCCTACACGTGCTGTTATTCGTGGCCGTGCTAAATCTAAAGAAAATGGCACATATGAATCTGGCAATACTATCGATGCAACGAACACAATCGAAACTACATACTTGAAACTCGAACAAGATGGCAAGGTAGTTCGTGAAATCGATAAATACGCCTATAAAGATTCTATTTCTGATGGCACCGACTTCCTTGGCGATGTTCGTGCTGCACTCGGTATTTAGTCTGTAGAAAGGACGATCACTAATGAGTAAACATAACACTATGAACGAAACACATGAACAAACAGGTATTGAATTAGTAAAAGCTGGTCATTCCTTACAATTTGAAGGCATCAGCGGGTACACATTAATTAAATGCGAAAAGTCCGCTAAGGGTGAAGATAAAACTATTACAGTTCCGGCATTATCCATGACGTATCAAGCACATGTAGCAGCTGCTGTATGCGGATGTAAAGTGGATGATATTTATAGTCTCCCGGCTGCCGATTTCACTAGAGTGTGCTTAGAGGTACAGAATTTTTTGCTCAATTCCGAAAAATAACAGACCTAGAACGGTATTTTACTGAGTGTGCAATTACGTGTAGTAAATACACTAGCACACCGATGGACTACTTCATTAGAGAGCTAGACGTGGATGAGTTCATAGTCCACGTTCGGCTCATTAGTGATAGTATCGAGCGCGAGAATAAAACAATGAAAGGGAGAAAATAATGGCCAATAAAGTCTTAGAAATGGCGATTGCCATTAAAGGTAAACTCGATGGCGGGTTATCTTCCTCCGTATCAAAAGCATCTCAGGAACTCAATAAATTATCTAATGTAATCAAAGATCAACAGGCGCAATATAGAAAACTACAAGCTATATCGCAAAAGACTGGTAATGTTAGCGATAGGAACGCAGCAATTGCAGCTGAGCAAAAGCTGAATTCTATGTTACAACGGCAAGCCCGGTTACGGTCTAATATCGCAAGTCAGACGGCGCATCAAAATGCAATCAGTAAAATGGGTGGTGCAAGTCCTTTAGCAGGTGCTGCATCAGCTGCGCAAGGTGCTAGTGCTGCGGTAAGTGGTATTACAGGAAAGCTTGCAAGTTTAGCTATGGTTGCCGCCGGTGGGTTTGGTATTGGTGCCATTATAGATAATGTAGTAAATGCTGGCGAAGCACTTTATCAATTGTCTAATAAATTACATATGACAACCGCTGAAACGGCACAATTTAAGAAGATTATGACATTAAGTGGTGTTGATGTAGAAGCGGCCGCAAAGTCTTTCGCTAAAATGGATAAGACTTTGGCTGGTGGCGGTAAAAGTGCTGAAGCTTTGCAAGGATATCTCAGTCAATTTGGTGTATCCTTAACCGATGCCAATGGCAAGTTATTGCCTATGAATCAACAGTTGGATGCAATGGCTAAAGGTTACCAAAATGCGGTAGCACAAGGCCGGGGACAAGAATTCATGCTTGAAACGCTAGGTGCAAAAGGCATGGAGCTTACTAAAGTATTTGAGAACTATGCAGATGCACAAGCGGCCGCATCACAAATCAAAGGCGTCGGAATAGATCCTAAATCACTCCATGAAATATGGCTACAAATGAACATCTTGAAAGCGGAAGCTACGCAAGTTGCATTAGGGTTGGCACAAGCCTTTATACCGATTGCTCAGCAAATATTACCGGCACTAATACCGGTATTGCAAGCTGTTGTAACCTTCATGAAGGATAATAAGGAAGCTATTGCCGCCGTAGTCACTAATGGATTGAAATTAGCCTTACTGTATGGTACGGCTACAAAACTAGCATCAGGTATTACTACAATTACCACGGCATTTAAAGGTGTAGAAACGGCAACGGGTGCATTTAAAGCAGCGGGTGCATTAATAGGTGGTCCATGGGTAATCGCTATCATGGCGATTATTGCGGTGATATACCTATTAGTAACTAATTGGGATACTATCTGTGCCACGTTAACATCTGTTTGGGATAGTGTATGTTCTGGATTGAGTTCAATATGGGATAGCGTATGTTCTGCTTTAAGTTCCGCATGGAGCGCCATTATATCCGGTATTATGGCTGTAATTAATGGGTTCTTATCATTAGGCCTTAGCGCATTTAATGCATTGAAAGCGGCAATAATTGCTTATGTAAATCTATGGTTAAACCTACCAACATATATTGGTATGGCCGTAGGATTCATAATAGGCATTATTTTGCGATTACCAGAGATAGCGGTACAAGTTGGTACTGCTGTTATATCTGCCGTTGTATCATTCGCTACTGAATGTTATAACTTCGCAGTTACTACATTTAGTGCTATGGTCGATGATATCTACAACTTCTTAATTAACTTACCTATGTACATGATCACTTTGGGCGCTGAGTTTGTAGCGGAGGTTATTTCGTTTGCCTCTGAGGCATATGCTACGGCCACATCATGGATTAGTAGTTTGGTTAATGATGTTATTAATTTCATCATGAATTTACCAAGTGCATGTGCTGATGCGGGAGCCGGTTTCGTAGCTGCCGCAGGCCAATGGGCAAGTGATGCCTATAATGCGGTATTAGACTGGATTAAACAAATTCCTAGTGCTGTATCTAATGCAATTTCAGGCGCATGGGATAGCATTAAGGCTCAATTTAGTGGTGGCTTTACTGTAGGTGTTCAAGCTGCAGGCGGTAATGCGTATGCTAATGGTGGTGTGATTACATCTCCGGAAGTCGCATTGATTGGTGAAGCTGGATATCCTGAAGTAATTGTACCTATTGATGGTAGTGCTAATGCTATGAACCTATGGCAAACGGCCGGACGAATGTTAGGTGTGAGTGGTGCGCAGTCAGCTGTAGCGCCTACTGTATCATTAGCACCTAGCGTGCCTGTTGCATCCTCATCTAGTAGTAGTGGGGCACCTGTACAGATTACATTTGCACCAGTTATAAATGCTGGTAATGGTTCAACTGATGATATTATGTCGGCATTGGATGCTAAAATGCGAGAATTTGAACAAATGATGCGTAGCTATACCGCCGGACAACGGAGGTTAAGTTATGACTAGTTATACAACAATACAAGGGGATATGTGGGATTTAATCGCTTATAAGGTGTATGGCAACGAACGATACATTAATCTATTGTTAGAAGCAAACCAAAAACATCGTAATACGGCGATATTTTCCGCTGGTGTTGTGTTAACATGCCCAGATGTTCCTGCTGATTCCTTGCCTGAATTCTTACCACCATGGAGGCGATAGTATATGAGCTTACAAAAGAGCCTAGCTAAGGTCCAGAAATGGAAGAAAGATTTAACGCCACAAACGAAGTTAGCACGGCGGGCATGGTGTACGATTGGTTACCAACATTGGGGGAGTAAGGAGTCAAAGGACATCACCGACGATATTAGTAAATACCTTCTTGATGTAACTTTCACAGATAACCTTTCAGGAACTGTAGATGACGTGGCTATCTCACTAGAAGATAGGGGCCGTCTATGGGTCGGCGATTGGTACCCTGTGAAAGGGTCATTACTAGAAGTGGCAATTAATACCGTAGCATGGGAGAAATTAGGGGATGAACAATTTACGTTGCCAATCGGCAAATTTGAAATTGATGAATTCGAGGGCAGTAGTCTTCCTGATGTAGTTAAAATCAAAGGTGTCGCTATTATCGGTAGTACTGACTTGCGGGAGAAAAAGAAAGACAAATCGTGGAAAACTACAACGCTTAAAGCGATTGCTACCGAGAAAGCAAAAGATAATAAATTAAAGCTAGTATGGGATGCGGATTTTGACCCACCGTTAAAAGATGCATCACAAAGTGCTGAATCAGACCTCGCATTCTTGCAGAAACTATGCAATGATGCGGGGTTTTCTCTTAAGGTATCCACTGAACAGTTGATTATATTCGATGATTACAAATACGAAAACGTGAAGCCTAAAGTTATAATTCGTAGACCAGGTGGCCAATATCAACCTGTACAGACGAAGGAAGGCGAGCAACCGCCTTTGATTATTACTAGAGCCTTATCTTATTCGTACAAAAGTAAAACTCGTGAAGTATATCGAGCATGCCATGTGAAATATACAGATAAGGATAAGAAATCCGTTATCGAGGATACATTCGAAGATCCTGACCGTAAGGGTCACACGTACCTTGCTGTATTAGAGGTTAATGAACAGGTTAAAGATAAGGCTGAGGCAAAGAGATTGGCTAAAAAGAAGCTAAGAGAAGCCAATAAAGAAGCCGATACAATGTCTTTTAGTTTTCCTGGCAATCCTCTTATTATGGCATCGGTTACGGTTAATCTCGAAGGATTTGGGGTGTTCGATGGTAATTATTTAATTACTAAAGCAACGCATACATTAGGGGCCAATTATTCAACGTCGATTGATGTAAGGAGGTGTTTAAATGGCTACTGACATATTATCCACATTAGTGGATATGATATTTATTGGAAATGTTTCAAGTACAATTCCTGAAGAAGGTAAAGCCGTTGTTACACGCCTAGACAGAGAAGGTGTTGTAACGGCGCCATTATCTGTCATTAATCGAGGTGCAGCACATGATAAGGACTATTGGATGCCGGCTATTGATGACCAGGTATTGTGCATTATGTTGCCTAATCGGTCCGGACGTGGGTTTTCCGATGGATTCATTATTGGCACATTCTTTAGTAGTGCGGATCCGACTCCAGGCGGTGCGGATAATGGTAAACGTGTGCTTACTGTTCCTGGAGATATGACTCTTAATGTTGGAGGTACTTTATCAATTAATTCAAGCGGTGGGGATGTAGTGGTCAATGGTATTTCCTTAGTTCATCATGTGCATGGCGGTGTAGTGTCTGGTGGTTCTACAACATCAGGACCAGAATAGGAGGTATAGATGTATATCGGTTATTTGGCGGATATAGTATTTTATACCGCATTAGATAATGTTCTTACTGTATCGGATGTAACGCGTTCAGGTAGTGCTCGATGGGAAAAGCACAATTTGATGTTAGAAAAGCCTGTCAAACAATTTAGCGGACCTGATGTGGAACAAATTACATGTAAGATTCTTATTTCTGCATCACTTGGACAATCTCCAGATAGTACTGTTAAGAAATTGCGAAATTATCGCGATATGGGGGCTGTATTACCGTTTATTATCGGTGGTAAACCTGTTAGTCAAAACTACTTTGTCATCATGTCTATGAGCGAGGATAGCTTATTCACGGATGCATACGGTAAGACTCAATCTATTGAGGTTTCTCTAACTCTTGAGGAATATTCGGATAATAATACAGTAGAAGAAAAGTCCATGCTAAATCAATATGGTCAGAAGTTCAATAAAGTTAATACGATATTGAGGAGGTTCTAGCCATGTCAGCAACGTATGAAATTAAACCAGTAACTGACAATAGGATATCGCTAGCACCTGAAAGTGAAGTCGCTGAGATTTTGCAGAATGTGCAAACGATTATTTCTACTGTTCGTGGTAGCGTGCCACTAGATAGGGAGTTTGGTATTGATGGTCGCATTATTGATATGCCTATCCATCAGGCGCAAGCTCATCTATCTAACGACATATTCCAACAAATTAAACGGTATGAACCACGTGCCAAAATTAGTGATATATCATTTACCGCCACACAAAATGGGGCGTTGATTCCGAAAGTGATGGTGACTGTATGAGATTATCTGATTTACCTAATGTTGAGTTTTTTAACACAGATAAAGAACACGTTCAACAGAAGGTATTTGATATTTACACAACAATAACAGGGCGAACCTTGGGAGAGGGCGATCCTGTTACTTTATTTTTAAATGTAATTTCGGAAATTATTATCCGATTATTGAACGATGCAAATTATGCAGCTAAACAAAATCTATTAGCCTATGCAGAAGGCGATAACTTGGACCATGTTGGAGCTGTTCCTGCTGCTGTTGAGCGATTAAAGGCAACGAAAGCGACTACAACAATTCAAGCAACATTGTCAGCAGTGCGCACGAACTCTGTCATTATTCCAAAGTGGACTAGAATATCAACTGGAAGTGGCGAATATTTTGCTACTGTTGAGGATTTGGTTATTCTACCAGGTCAACTTAATGGATCCGTAAAAGCAGAAGCACAAATTGCCGGGGCGCGAGGCAATGGGTTTAAGCCGGGCGAGATAAGTACAATTATTGATCCTATAGCTTATGTGGATACGATGCGTAATATAACTCTATCTGAAGGTGGTTCTGATACAGAGGACGACGAATCGTATCGCGAACGTATTCATGAGGCTCCAGAATCGTTCTCTGTGGCAGGCCCTGAAGGGGCGTATGAGTATTTTACAAAGTCCGCGTCGCACCTTGTGGCAGATGTAGGCGTATCTTCTCCACGTCCAGGTGAGGTTAATATTTATCCCTTATTAGCAGGAGGAGGACTTCCTGGGCAAGAATTGCTCACGACTATTACGGATTATTTATCTGATAAGAAACGTAGGCCTCTGACTGATAAGCTAACTGTATTAGCACCTACTACTACGCAATATAACATCGACGCTAAGTATTACATTGAAAAAGGCGCCGATGCAACGGTGGTAAAAGCTAAGGCAGATAAAGCAGTTAATGACTATGTTATATGGCAAAAGTCAAAATTGGGCCGTGATATAGTACCCAGTCGATTGGTTCAAATGCTCATGGATGTATCCGGAATTAAACGCGTTGAAGTAACGGCACCTATATTTACCCCGATTGCAGAACAAAGCGGCGTGGCAGTAGCCAATACAATCGCTGTAGCGCTCGCAGGAAGTGAGGAAGAATGATACTTGATAGCAAGTATACTAGTGCGGAGCATCTTCCGTCCTCAATCGATAGGGAACCAGTTAAGTCCCTTGCTAAAACGTGGGATGATATGCTGGCCGAATTTATGAATACGAATACTCTGCTATTATGGTCGTCTATTGATACTGAACCAGAGAGTGTAATTGATCATTTAGCGTATCAATTACACGTGGATGACTATGATAGTGGGTTACCGATAGAGACTAAACGTGAAATGGTGAAGAACTCAATTGATATTCACCGCCATAAGGGCACGCCGTATGCTGTTGAAAAGGCCGTACAGACTATATATTCTGATTCAAAAACCGAAGAATGGTTTGAATATGGCGGGAAACCGTATTATTTCAAGGTTACGCTAATCACAGCCCCATTAAGAGGCGAAACAGATATAGCTAAGCTTGTACGTGCTATTAATGCGGCTAAAAATGTACGGTCCTGGCTAGATGGTATTGAATTCATTCGACGAATTAACTTCAATAAGTATTTTGCCGGATGGTGCGGTGTATCTAGGAAAGTGAATATCAAGTGTGATTTCACGAATGCATGGCGCATTAATTTGAATACCCATGTAACGTCTTATACTGTTGAATCGAAGAAAACTAAGATTAATGTAGTGCTAGATAATAGCGTTAGATAGGAGGAATATATGGCAGAATGGTCAAATGCAACCATGACTGATGTTGGCGCGAATTTGCAAGCGAAGGTGAATGCAGGCAAAACTAAGCTGACATTCACTAAAATCAAAGTAGGTAGTGGTGTTAATTCAACGAATCCATTGGCATTAACTGATGTAATCTCCTCTAAGTGGGAAACTACTAATTTTGTAGTTAAGCTAGAAGGTAAAATTGTAAGTGTTGATACAGTTATAACTAATACTGGTATACATGAAGCTTTCCGAATGTCTGAAATTGGGTTATTTGCACAAGATCCTGATAAAGGCGAAATATTGTATGCATACCTTACGGACCCTGAACCGGACAGAATGCCGGCAGAAAGTGGCTCGGTAGTTGTATCTCAAGAATTAACAATCGGAATGGTATTTAGTAATACAGGAAATGTATCGCTAACTGTTAATATGGGTGCGTTGGTAACACGTGAGCAGTTAACAGAAGCAGTTAAACAACATAACACAGATATTTCATCTCATCCAGCGATTACAGCTATGATTGCCAAAATCCTCGGTGCAACTAACTGGCAAGAAAATCCAGTTGCTACATTGAAGGATATAAAAAATCTTATCGGGCAAGGTGCTATCGTGGCATCTAAACTCGATGCCAATGCTGGTTTCGTAAAATTTGCGAATGGTTTCACTATCCAGTGGGGAGTGGGTGGTCAAGATAACGTAACTAAGACAGAGGTACGATTTCCTATCAAATTTACAACTTTATTCATGGCGAACGCTATAGATGCGTACTGGTCAGGCTCTGACACGCCTAGGTATTTCGCTAACTCCGTGTCAGAGAGCAACGCAACTAAGGCCGTATTTTCGGCAAGTGATAGATATGCTGCTTCTTATTACTGGTTCGCACTAGGAATAATCTAATTTCCTAGGATAATGAACATAATCTGATCACCGACACCTTTGGATATTAAGCCTTCCCTACGACCATCCAAACAAAACTACCTGTGTCCACTCTGTTGGTTAAGAATCGGATGGTGTTTCTATTAGCTTGAGAAAACCCACTGTTCCAAGTAATAAAACATTCTGATCCAGAAGTAGCAACACTAACAGAGTCATCAGTGGCTAAGGCAATTAGTACAGTGCTGCTAATCGGCAGCGAAATATCTTTATAGTATTTATTGGAATCAAACCAAGTTAATCCCCACTGGGGAGTTATTTTAATAATTCTATGGCTTTTCGTAGCTCACGAATAGTCTTATGTGTGTATACCCTGGTGGTAATATCGCCTTGTTTGTGGCCTAGTAAAGAACGTAATGTGTTGGGCGGTGCTACCGAGTCAAGTAAACTTGCAAATGTATGACGAGTATCGTGGATAGTATGCTTACAATTTAACTGTTTCATAATATCCTTGAAATTCTTATGGAATGTTGTGTAACTGATGGTGAATAGATATGCTTCGGTGCTGGTGTATACTTGCTCTATTAGTGGCATGATGCGGTGATGTATAGGAATGATACGGCCTTCACCGGCTTTCGTTTTAGCGTGTCTTACGATGAGGTATGACGATCGCCTATGGATATCTTGCCTACGTAAGTTAAGTAGCTCGCCGATACGGAGCCCGGTGTAGAGCAACATTAAAATCATTTGGGAATAAGAATTATCTATCGCCCATAATTTGTTGATTTGTTGGCGAGTGAATACTCTTCTTTTAATCATTGGTATATTGGGCCCTAGATTTAAGTGTGAGGCGTAATTAGTGATAGGGTAATCTTGGATGATTGCGTAATTAAATAATTGATTAAGTAACGTGCGGACTTTCTTACATGATGAGTAAGAAAGTCCTTTTACGTGCATGGAATTAATCACATTTTGAAGGTGCTGAAAATGAATATCCGTGATAGGCATATCCGCTATGTTGGATATGTGTTTAAAAGCAATATGGTAAGACTTAACGACACTCTTAGTAATAGCTTGTGAGTGAATAGGCAACCACTCGTTAAATAGTTGCCTTAATGTAATGGTATTGCGTTGTCTACGTTTTAGTATAACGGCGTAACGGCGCATAATTTCACCTCCGAAAGGATGCTACTATGAATCAATATGTATTTATTTTAAATGACAAAGGGGAGCGTATTACATCCCTGTGTGATAACACGTTGAGCCGTGATGATATTATGGCGCAAGCTGAACACGATTATCCAAATGCACAATATGTGTATTCTGCAGATGGTGACAGTATGCTAGATGAATTTATGAGCGGTAAATTGTATGTAAACGGAAAATTTATTGAGCCTGATCCGTATGTTCCTACAAAGGAAGATAAGATTAACGCTATAAAAGCTGAATATGAACCCCGCTTCAAAACGCTAGAAGAAGCGCAACGTAGATTGCTACTTATGGGAAAACCTACTAATGCAATTAGCACTCAATATATCAAGTTGAATAACGAAATGGTCGCACGAATTAAGGAGGTGCAATAATATGCCTAAATATATCGGTGATAGCAAAGTTCCTGTTATGGAATTCTGTGAGTACTGCTGGGAAGTACTCAACGATGACGGTACATGTCCAACAGAAGGATGCGTGCACAATGATTTAATGGCTTTAGATGAAGAATCATAAGGGCATGGGGGAGTGAATGGATATTCTTAATGATATTTTAATCATGCTCATCAGTGGTATATCGCATGAACATATAGTCAGTATGGGGGTAGTGATTATTTTAACCACTACATTGTTATTTGTGGACACAATACAGCGGATTGCTGCAGAAGTGTTGCGGTATAACAAAGATAATCACAGGCCTAATAATCCTATTACACTACTAACAACATTGACCTGGTATGGATGGGGAAAAGGTAGGTATATCGATGAAACTACCGGTGAACGGCGTAGATATTTAATGAGTGAGCGCCTTAGAGGTGATCTATTAAAGAAACTATGCATACAATATCCGGCATGGATGATACTATCCATTGTATTTATTTCATTACCTGATATCCCAATACCAAACACCAATCTATTCTTAGACCATATATTCTCTTATGCATTTATGCTGATACCATTCTTCGCTGAGTGTTGGTCTATTATTGAAAACCTACGTGAAATGGTTGAAGATGACCTAATTGATATAGGAAAAATATTTCAATATACGATTGAAATCATAAAGGCATGGAGGGGTAATGGATAAGCTAGCGATTATTAACCGCATTAAGCGGTCATATAAGTCCATTCGAATAGCTGGCATACGGCCAACAGGTGTATTAGCAACGAGGGCATTGGTCCTCGTCATGCTAGTACCGATGATATTAGTCGTTGCCCAGTATGTGCTATCGACGATTAAGGGGTATGTATCCCCTGAAGAGAATCAGCTTATCGATAAGGGTATTCTTATAATTGACCATATATTCGTACCATCAGTGCTTATGACCATTGTTGGATTGTGTGGCATGTTCATCGATAAGAACCATAACGGGATTCCAGATAAGCTTGAGGAACCAAATACATTGCCTATGAACAGACCTGGCATACAACAATTAGAGGATGATATTAACCATGACGAGAGGGGGAAATAAATGTTTAGACAAATTACAATGGACGAGTTAAAAGACCTAGCGCTAGATGCCTATGGCCAAATTGAAAAGGCGTACTATCATTGGACAGGGGTAAAAGGTGGTAAGCACTTCACAGATTACCATATCAACATCGACCGAGCAGGTACAATGTGGACCGATATAGAGGCCTTAACCGATTATAAGGAACACACCTATATGCGCAATAGTAACGCTGTAGGCATTGCCATTGAAGCGTGTTGGGATGCAGTCAGTGAAAATAACCTAGGTAGTGAACCACCAACAAAAGAACAGTTGGCCACTATGACACAAATTATGGCGGTGCTTACTATTAATGCAGGTGTGCCACTTGACCTACAACATCAGATGACGCACGCCGAAGCAGCAGATAATCGGGACGGATTGGACCTCTATTATTTAGATCCGACGGGCTATCCAAATAATACGTACGGCCCAGACTCCAACGTTGACCGATGGGACCTCTTGGTGTGCCATGAGGGCGACGAACGATGGAGTGGTGGTGACTGGTTACGTGGCACCGCTCGATGGTGGGGTGCTCAGTGGGGTAGTACAATTTAGGAAGGAGTTACCATGTATGAAACTATCAAGAACAAAGTTATATCTGCGTTTACTCTTAAGCGTGTTATTTGTGGTGTGCTTAGCATTATTTCCATCTATTTCGCATGCAGCCTCATCGGAGGGTACCTCGACACAAGAGCCGACTATCAGCGTACCCGTGAGCAGTTGGAACGAACTCAAAGGGCGCTTGATGAAAGCAGAAAGCTCAATCAACAACTCCGAGAAAGCATTGCAGCAAGCCAACAGCTTAACCGCGACGCAGGGAACAGCATTAACAGAATTGAAGATTATCAACGAAGAACGGACGAAGGAATTGAACGCGCTCAAAGCAATCAACGAGAAACAGGGGCAAGAATTAACGAAAGCCTCCAATCTCTTGACAACGCAAGAAGCGAAATTGAACGAAGCCTCGACCTCATTAGAAGAATTGACAGAACAAATCAAACGCAACAAACGAACCGAACAGCGCCTTAAACGGCAACGTGACACATGGGCCGTGGTAAGCGGTGTATTTGGATTGGCAGGTGCAATTCGTCGATGACTGAGAGGTGATCCATACATCTCCTGAGCATGAGCAGGTGGACTCATGGATTGACTATATAAAAGACCTTACCAGGATATAACTTGGTAAGGTCTTTTTTTTATATTTAATTTATTGCATACAATCTAAAAATATGGTGTAATTAGGGTAATAATAGGAGGTGGGAGTAATGCTGAAAATTCTTAATTGTAATCCACATTTTATGAGGGACCCAGTGCCCGTGTCGAACTATGCTGAAGCGTGGGACGTAATATGTTCCATGCAAAGGGAATTAGGTCAAGGGATACTTGCTGTTGACAGAGAGGCTTGGGAAGTTTTGGGATTAGCTGAGCATTTCCCTGAATTTGTTTGGAAAGAAAATGTAAAGGCGGTATACATTAATAGCGATAAATCGTTACTGATTCCTGCCCCAAGGAGATATTGTAGATCTAATGTTTTGAAGCTTATCAAATTCTTTGGACTCCACTATTCTATCCGAGAAATATAAATGTATATATGACATCATTTTGACATCATATTATATAAAAATATAGTGAAATATAAATAGATACGCTAGTAATCGAGCTAGATATTTGCTGTATTTATAAGTTTTGTGTGTGAACTTTAAATGCCACGCCATCTTGAGGGGGTGGTGAGCTAACGCTCGTGCGGGTTCAAGTCCCGCCAACCGCACCAAGCTAATAAAATAAGGGTTTACAGGTAATTCTGTAAGCCCTTATTTTTATTTATGTAGATATTATAGGTATCTATATCATCACATTCCTCCGACACAGCGTTGGCATGTGGTAAATCGCAGTAAATCAAATTTACAACCAATAGTAACACTCTTCCTTGTGTATTATTTTGAAAGCGCTTTTTTGCTTTCTTTTCTTATTTGTTGGATGCTTTTAGTCGGTGTTTCTAAATCTTCAGGCATGGTACCGCCTAATTCTTTGATAGTTTGACGTACCTTTGCCCCAACGTCATGATGAATTTTATTAGCGTTTTCTTTTCCTTTTATTCCTTCCCGGCGCAATTTTTCATCAGTTTGTGTAGATCGGAATAGATTAGCAGCAAGTTCGGTACTACCCATATGATCTAAAATCTTCTGAGATTTTTTTAGACCTTTTTTAGCGTGAATTTGCTTTACGCCCAAACCTCCATATAAACCCTTATAGCCTTCGTTTTGAAAAATAGCATAATCTTTAGGTTCTTTTATACCTGCTTGGTTAGCAGCTTCAGCTAAAGATATATTATGCTCTTTAATATCTTGTCGGATTTGTAAACGTAAGCTATCTTCTTTTTGTAATTCTAATTGCTCTTGCTCGTGAGTTTTCACAGCAAAATAGGTTTGAGCTAATGCAATTACCTCTTTACGAGGATTGCCATTCATAGCAATTAAGTAACAAGCATATCTAGAGAGTACTATATCTTGTATACTACGTTGTAAGTTAGCCCCAACATCTACCAATTTGTTGACGTCAACAAATTCGGATTGAACTGCATGACCACTGGTTTCACAAGCACTTTTAGCCTTTTCAATAATTTTACTAAAATTTCTCCATTCTGAGTATTCGAGTATTTCTTGTAAATCTCGAGCATACCAATACTCATTGCCATCATCATCTATTTGTTTAATTGATTCAAAAGGGGACTGATAAGTATTGTCTGCATTGCTAGGACTCTCTTCAGGGAAAAAGAAAAACATATAAACCTCCTGTTATCTATATATCTTACTTATTTTTATGTCTAGATTTTATAAATTCTATGTAGTTTACCACTTCTTGCATTTCCTCTTTAGAGATCTCTCTTGATGCGGAAAACAATAAACGCATTTCTGGGCGTGTGTGCAATATTTCAGCATACTCTGCAGCTTCTTTATCTTGGTAGTATTGCTCATCGTCTTTATCCCAGCCCATTATCACTGCAGGCGATATATTAAAAACCCTTGCTAATCCTTCGATTTTATCAGAGGGAATATTTGTAATAATATTATTCTCATATTTATATAATGTTTGTTTTGAAACACCGATTTTTTCACCGACTTCTTCTAGAGTCATCTTATTGTTAATTCTGAGATTTTTAATTCTATCTCCTTTATTAGTAGTCATGGGTTTACCTCGCTCTTAATAGTCTCCTTATGAGTTAATATTACACTGTCTTAACTTTGTGGGCAACATTTTTGTAAAAAATATTTACAAAAATAACTTGATAGGTTACTATTGCTAAATTGTTCTATAAGCAACTTAAAAAGTTATAAATAGAAAAAGGAGGCGATATATTGATTGATGTAAATAAGTTAAAAGGAGCAATTGTAAGTGCTGGGAAAATACAAAATGAAGTAGCTAAGGCGCTCGGAATTACACCTAAAACATTCTTTTTAAAATTAAAAAAGGAGTGTTTGGGCTGATGAGATTGAAGTTATGATTGACTACCTTTCAATTGGAGCTCCTTTGTCTATTTTTCGTGCAAAGAATGCAACTTAATAAGTTACAAAAAATGAAGTGATACAAATGAAACAAGAAACAGGAAAAGTAAAATGCCCCAAATGTAATATAGAAGTGATAGGTGGAAATTTCTGTGAACATTGTGGGGCAAAATTATAAGCTATATGTGATTGTTGGGTAGTAAAGAAAAAATATAATTGTGGTTTTGATAAATGCAAAGGTTATAAGTTGTTAATTGAATGTATCAAGGGAAAAGAATATTTCTAATACCTTCAGATATAGCATCAGAAATAAGTCTTTTAGCTAAAGAACTGATTTCAGAAGGAAGCTTATTAAACAATAATTTTAATTGTAAAGCGGATACCTCTGATTGAGGAGTTTCAGAAAAAATAACTGGTAAGTAGGACATAAAATGTTTTTTTTCTTCTTCTGTTAATTGGTCCTGCATGTCTAGAAGTTTAGAAATCGAATTTATTTTTTCTTCTGTCCATGGGAATGGATATCCACAATGATGACAGTATTTAGGGGGTGTATAGGTTGAAAAGCTAATAACACCAGGAACATCATATTCACCACGAATAGGGGTATTACAGTTTGGACAAGAAGTTATAGTTTCAGCTCTACATTCAGGACAGAAATTAGATAGGTGAGCAGAGTTATGAATATTAGATGTAATAACATGACCATTTTTACAAACTTGCGCAGTTCGATAAGTACCCATTATAATCACCACCTTTAAATTGTAGGGATATGGCCCAAATTTTGTTCATGTTTAAGCCATGAAATAACATCTGATTGGAGCGTAGCATAAAACGGTTGCACAATTGGGGTAATAAGTAAAAGATCGTTGTTATCTATTTTATTACTTAAATATACGTAGACTGAGTCGATATTATCGTTGGTAGAAATTAACCATTGAGAATGTAAACACTTAATATAGGCATCATAAGTTTTGATTGCATTGATTAAATTTGTGTAATTTTGACCTTGCTTATTTAAATCATAACTTACTAAGAATACTGCCATTATAATCACGTCCTTTTAGAAACTTAAAAGAAATGGAGAAAAAATGATTAAACAAGAAAGAGAAATTAAAGATAGCAAACACTTTCAGGTTAATAGATTAGCATTTTACGTTCAACTTAAAACAATGACTGTAGATAATCTTAAAAAATACCCACATTGGAATTCAGAAAGAATGGATGTAATCTATTATTTAGCCAAGTATGGAGAGAAGGAGGAGTTGAAGAAACTATCAAAGCAAACTTTGTGCAATGTGGATTAAAGTATCAAATGTTAAAGGGATTGCCTTTTGGATAGCGTAATCTTTTACTTTGTTCCATATCGTATCGCTAGATAATAAATCAACAAACTGTTGCCCATCATGTGTTAATGCTAGTTCTAAATATAAATAATCTCTTGATTTAGAGCTAGCATTTAAGCCAGACAATAGACCATTCTGTATAAGGATATAAATGTGATAGTCAATAGTAAGCCTGTTGATATCAGGGAAGTTGATTGAGTCATTATTATTAACTGTTGGAAGAGGGAAATCTTGAACTGCTAATAATATATCTCTGCACAAAGAATAATCTATTTTCATAGTTTCACCTCCTTTCGTTAAAGGAAATAAGTGATATTAGCATATCTCATTGTCTATCACTGCTTGAATTATAACAACAACTTATTAATAAACATGAAATAAACATGAAATAAATATGAAAAGAAAGTTAAAAGAGGATCTTAAGAAGAAAATAGATAGAAAATAGTAAAAGAGTAACCAATATTATATAAGTGGTACTTATATAATATTGGGTTCATAGTGCTTAAAATTGTGTCAATTAATCTTAACAAATATCTGGTAGAGGCAAAAAATCACTAATAGGATAGAGGCGGCAATTAAAAGTAGAAAAAATAAAATTAGAACTATAAAAGCTGAAATTGAATGAATAAGTATGATGTGGAATATTTTAACGCTTGCTTTTATACCAATATTGCCTGGGCAGAAAAGAGGGATGTATATTATATTCAGAAATTATATTTAGGTTAGTAGTTAATGAAACTCAATTATGGTGTCAAGTGAAAACTGCTTTACGCGGAAAGACAATTGGGTAAAATAATAATTCTGTTTCTGCCAGTGAAGTGTAAAAAGACTAAAAAGGATATAATAAACTAATATATATGGAAAAATATGATAGGATGTTTCCATTGAGATTAAAAGGTAAGAAGAGATTTATAGGGTATGTAAGTTAAGGAGTATCTTATATATTCTGGTATAATCCTAATCATCAATTATTTTGTTCTTCCTTATAAAGTGATTCTTTTTATAACTGTATTGGCATACTTCTAGATTCTGTGTACAATCATAGTAATTAGTAATATACATTTATATATAGTTTTCAGTATGAGAGAAGATTATGATTTTTAATTATGGCGAGACATTACGTATCCGAAGGGATTTATATACGATTTTAGGCAAAATACGCTATATTGATACTCATGGAAAAATTGGGTATGAGTATAAGTTAGTTAGACATAAGAATAATGCAGAGTTTTGGCTCAGTTGGGATAAGAAGCGAGATGCGTACCAGTTTTCCAAGTTGTGTGGAAAAGCACTACCAGCCGATATGAAACTCATAGATAGTGGTTATGAGATGGTAACGGGCACTTGGGGTGAGGTAGACGTAGGTACTACTGATACTGCTAAATATAAAGAGTATGAAAATGCTGATGGTACTGCTACGTTTTCTGTTCAAGAGTGGGCTTTTGAAACGGAATATTCAAAAGGCTTTTACATTAATAAAGAATACGTATCTGTCGAAAAGGATTCAGAGGTAACCGAGTCTATTCTAGATAAAATGGATACGATTAAGAAGCTAAAGTTCATAGGACCAATCGGTTGGATTTTGGGGAACTTACTACTTTATATGCCAATCTTTGATATAAAAATATTGAATGATGTACGGGATGTACTTACCTGGCCTTATATAGTAGCTGGGAGTATAGTCCTTGGTATCATTGTGGCTTGTGCTTTCATTATTTCCAGAACTATGCGTTGATGAAAACACATTGGTTATATAGGAGTCCCTTTCGTGGGGCAAATAAAAGGTCGTAACATGTATTAATACATATTACGACCTTTTTACTATAGGATTTATTTGTTAGGGGTTAGCTATTAGCTTCAGCTGGTTGAAGTTGTTCAAGTTCAGCTTCTTTAGCATCTAATTCTTTGGCGCCAAAATGAGCCAATACACAGAATGTAATACAAAGAACACATGCTACTAATAAAAGATAGAAACCTGCATTCCAACCAAATTTATCTGCTAAAACACCAAATAGTGTTGTACCTAAGTTTGCACCAACAATGTAACTCATGAATCCACGAAGACCAACAGCAGAACCTACTGCAAATGGTGGTACAATATCCATAGTTTGTACTGAAGCTAAGAATTGAGGAATGTAGATTAAACAACCTACAATAGCAGCGAAGAAAGTAACCCATAAGAGAGACTCGCTTTGCCAATAACCAAATATACAGAAGAAGATAATACTTATAGCAATGATTGCAGGTGGCATGCGATAACCTTTAAAGAATTTATCGGAAATGTAACCAGCAAAAATAGTAGAAGGGATAGCCGCCCATTCAAAGAATAAAAAGGCAACAGACATTTCTGCTTTGGAAAACCCCTTTACTTGCAATAAATAAATTGGAAGCCACGTAAGCATACCAAAGCGAATCATGTAAACGAAGGTGTCAACTAATGATACATACCAAGCGTTTTTATTTTTCAATACGTATTTTACAAAGATTTCTCTTGTGCTCATATGGGGGGCTTCAGAACTTCTGTGCGCCTTATGAGCTGTGTCAGCGATGATTTCACTTGTTGGTGGTAAGCCTTCACGTTCAGGGCTTTCTTTGATTAAGAAAGAAATGGCAATTGCTATGATAATTGCAATAAGCGCTGGTACACCATAACTCCCTAATTGCCAGTGATCTGTAGTAGTAAAATATAATGCGGCAGCTACGATTGGGGCTACGATACCACCACCGAGATTATGGGAAATATTCCAGATAGCTCCATAACGGCCACGTTCCTGTTTTGGGTACCATTTAGCTAAGGTGATAAAGGATGGTCCTACACCAAATCCTTGGAAAAAGCCATTTAGTACTACTAAAACTAAGAAGAAGGCGAGACTATCGGCAAAGCTCATAAAGATATTGATAATTGCACAGCAAATGAGACCGAAAGCCATAAACTTGGCAGGACTTGCTTTGTCCGCAAGACTACTCATAAAGCCTTTACTTAGACCATAAGCGATAAGCATACCACTAGATAGCAAACCAATTTCTGTTTTGCTCATATGGAGGATATCTGATAAAAAGTGTGTTGATAAGGCAAAGTTATTACGAACAATATAGTACGCAGCATAACCTATAAAAATACCAATTAATGATTGCAATCTATATTTATAATATAGATTCATAATCATGCTTTGTGGCACTGATGATTTTGCCTCTTTGGGTTGTAGAAATGAAAACATAGTTATTACCTTTCTTTCTTAATAACTAAATCCTATTGCATTGTTAATACTACCATTTCTATAGAATTCATGTAAATGATTTATGAGATAAAAATATTAATTTGCAACATTAAATTGTTTATTATTAGCTGAAGATACGTATAGAAAACATTTGAATTATAGACAAGTACTTCTTAATATATTAGATTAAATATATGGGGAGGTTATAATCTATGAAATACTTACGCCGTGAACTTAATCAAGTAGAAAAAGAATATGTAAAACAATTTGGTGAAGATTCTTTAAATCGTGTCATCCTTCATGATCCTAATACAAAGGATAAACAAGAGGTGCAAGATACTATTGATATTCTAAAAGGAGCAATTGCAAAAAATAAACCTCTAGAACAGGTTCCAGAGGAGATGTGGAAGCTTATTGAGTTTTAATGTATATGAATCCCATAAATAAAATAAAAAGGCACATTGTCATATGAACAGGCTATCTAACAATGAAATAATTTTAGATGGGTGTTCAATACAATGTGCCTTTGTTTTATAGTTTGTAGAGTTCAGGTTTGCGATCTCTAAAGATGTTGATTTTGTTACGGATATCTTCTACTACGGTGAGGTCGATATCTACAGATGAGATGCCCTCCCTAGTGTCCATTTCGAGGAGGTTTGTACCCCATGGATCGTATACAGCGGAGTGACCAGTGCTTTGAACTCGACCTACTGTACCACAGCCGTTGACAGCACATAAGAAGAGTTGGTTTTCAATGGCGCGCACTTCGTTTAATACTTGCCAGTGGCGTAAACGCATAGTAGGCCATTGAGCAGGTACAAATAATAACTCTGTATTTGATAATGCAGCCATTCTTACGAGCTCAGGAAAGCGAATATCGTAACAGATAACCGTACTACAAGGAATACCATCCAATTCGAAATGAGTGGTATGCGTACCGCTAGCGAAGTATTGGTCCTCTTTAGCAGGACTAAATCCGTGCATTTTGGAATACTCTCCTACGAGCTTGCCTTCACGGTTGTAAGCATAGGAGGTATTAAATACTAAATCCTCTTTTGCTACGGCTACAGAACCGCCCACAATGTTTACATTGTGTTCTTTTGCGAATGTACTTAATAAAGCTTTTGTTCTTTCTCCATTTCTGTCAGAAATATTGATTAAATCCTTAGATGGATGAAATCCTGTATTCCATGTTTCGGGCAAGACGATAATGTCAGGCTTTTCTGATAGGGCTTGTGAAAGTAATTCTTGGACGCGCGCATAATTGTATTCCACTTCGTTTACATGGACGTCCATTTGTATAAGGCTTAAGCGTTTTTTCATAGAGAATCCTTTATCTATTAGATGAATATAATTCTAGTAATGTGTATTATAATTAGAATATTAAAGCATTATTGAGTGTATTACAATATAAGAGTCGATAAAGCTAGTTTAATTTTTTTACAATCTTTTGATAATAATAGTTTGCATACTATTTATGGAGATATAGGTTATTACTTTAGATAATGTTAGATCTTTTGGTGAAAATATGGAAATAATAGATGTTATAAATGCGCGAACTAGCGTACGTCGGTATAAAAAATCTTCTTCGGTTGGAGAAGACATAATTCAAAATTTGGTAGCTCTCGGAATGCGAGCTCCATCCCCTAAAAATCGTCAGCCCTGGCAGGTTGTTCATGTGACGGGCGTGGAGAAAAAACATTTCGTGAATCTTGGCTTTCAAGTGCTAGAGCAATATAAAGAACGAAAAGAACATTTTGGTAGTTTAGAGATTAGTCTTAAGGCTATGCAAACTGCTAGTGATTTACTCTTTGTATATAATCCTTACGATCATTTGTCAGATTATGCTCAAGTGTGGGAAAAAAGTGATTTACAAGCTATTGGCGCTTTTATAGAACATATTTTATTGGGGGCAAAAGCAATTGGGTTAGGTACATTGTGGATGAATGATGTGTATTTTATGCAAAGTGAAAGTAAAGCCTTTTTAAATATTCCTCACGATGTACAGGCAATCATTGCTATAGGTATTCCAGATGAGTCCATGTATCCTAGACCTCGAAAATCGATTGATGAAGTACTAATAAAGCGTTAATTTTTACTATTCTTCATGGAAATGTTATAATATTCTGTATATAATTGTGTTCTAATAGAGGAGGACCTATGAAACGGATTCCGTTGGTAACACTGTTAGTTTTGGTATTGGCAATGGTTGTGGCAGGTTGTGGATTGCTTTCACAAAAAACAGAACCTACTAGTTCAGTACCGCCTGTAAAAGAAGTTAAGATGGTACATCCAACGGGTATTCCTGTTCTTATGTATCATAAAGTCGGCGACGACAAAGATAATGATGCAGTTATTCGGGAGGATTTGTTTAGAGAACAAATGAAGTTCCTCAAGGATAATGGCTATAATCCATTGACGATGGATCAATTGTATGATTATGTTGTAAATGGTGCTGCGGTGCCTGAAAAACCTGTTGTTTTAACCTTTGATGACGGTTATGCAGATACATATTCTATCGTATATCCACTTATGAAAGAATATGGATTCCCGGCTACTGTATTTATCAATCCTGGCGATGTTGGGACGCGTCTAACTTGGGATCAAGTGCGTGAAATGCACAAAAATGGTATTACTATTTCAAACCATGGTTTCCAACACATAGAAATGGGCCAATTGTCGGAAGCAAAACAAATTGAAAATATTACAAAGGCCCAAGAGGCACTTGCTAAAGAAGTAGGCATTAAGGATAATCCTTGGTTCTGCTATCCATATGGAGATAAAAATGAATTCACCGACTCAGCATCTAAGAAAGCTGGCATTAAAATGGGGATGGCTATGAAATCTGGCTGGGCTCATACTGGTGATAATCCATATAATATTTTGCGTGTTTGGGTAGGCAATGCGGTGGATATCAAGCATTTTGAAGAACGCATTAGCACCGAACATTTCACTGATTTATAAGGAGAAATACATTGTTCAAAAAGAATTGGGTAAAGTTCATCATTATGGTGTTCTTATTTACCGTTGTCACATCACCCTTCGTGGTGCTCTTTGGACCATTTAATAATGTAAAGCGCGCTGTAATTGGTGCTATCTTACAATCCCGCCATCCTCATTACATTACATGGTTGTTTAATGAAGACGAATTACAATCTATTTTGGGGACTGTAGGGGTTGTTAAAAGCCAAGATTTGTTCAAGTTTAATGCTCGTGAAGATAAGACTTTAAATCTTGAAAAAATCCAGTCTGCTCGTTATGTAGGCTATATTTTAGAAATTCCTGATCCTCGTCGTATTCAAGTAGGTACAGCAGCTAATATTCAAGAAAAAGGTGATACTACAAGTAATATTGCGAAAATGAATAATGCTGTAGCAGCAATTAATGGTGGTGGTTTCCACGATCCTAATGGTACTGGTACAGGTCGTTTGCCATATGGTTTCATCTTGCATGACGGTGAGTACGTTATCGGCAAGGATGTAGGCCCTGATGAAGATGTAGACTTTGTAGGTTTCTCTAAATCTGGTAATCTTATCGCTGGTAACTATGATAAAACTCAGCTTAGTGATATGAAGGCCATGGAAGGTATTACCTTTGGTCCGCCTCTTATCGTCGATGGTAAGAAGATGATTACCGAAGGTGATGGAGGCTGGGGCGTAGGTCCTCGTACTGCTATCGGTCAAAAGAAAGATGGCACAGTTCTATTCCTTGTAATCGATGGTCGCCAACCAGGATATTCTATTGGGGCTACCTTGCGTGACGTACAAGATATTCTATTTGAAAAAGGTTGCTACATTGCAGCAAATTTAGATGGCGGTTCTAGTTCAACTTTGTACCTAAATGGTAAAGTCGTAAATAAACCTGCCGATTTGTTAGGGGAACGCATGATCCCAACGGCGTTTATCGTGAAATAGGAGGACAGATGAAACCTTTTACGCGTGTACTGAGCGCCTTTGCGGTAGGTATTCTTCTGCAAGGTGGGGTATACCTATACCTTGATCAATATATGTTTGCACCGACTACAGAGTTTAACGTAGCAGGCGCATCAAAAGATGATACTAAAAACTTCCCTGATGTGAAGGAAGGCACTAAATATGTGTCCTATGACCGTCAATTTATGGCCGTTGTTACAGAAAACTCTTTGAAAATTTACAAGGCTAATGAAAGTAAGCCTACAAATATCGATTTGAAGGGTCGTTCGATTAGTTACTTCAACTGGATGCCAGACCGTAACTATGCTGTCATGGGTTTATATGACTCCAGAGATGTTGTCATGGCTCGTCTTAATGCGGATGATCCAGAACACGAAGTTGATACGAAACTTGAAGACTTGCCTCGGGGCAGTAAAATTGTAGATGCTGCGTACTCTGAAGCGACAAATGTGGTGTATATGAAGGTAAAAGTTCAAGAACACACATATCGCATTTATCGTACCGATGCTAACTACGATACACGTCGCGTTTACATGCAAGCTACTGATATCGGTCATATCGGTGTATTCTACGATGAAGATAACTTCTTCTACGATAATGTGAGAACTGGGGATGTATTCATGTTCAACGGCATTGAAGGGGGATGGCGTGTTATCAACCCTGAAGGGCGTTTCCGCTTTATCGGTGTTGATATGGACAAAACCATCTACATCGCTCGTGTTGATGAGGACAACAATGCATTGACTGTTTACACTGGTAAACTCGGTGTAGGCTTCAATCCAGTTTATAAATACAACCACCCTACTACATTTAATGAATTGACATTATCTGATGTAAAAAACATCATTAAGAATGGTAGTGAAGAAACTACTAAGGTAACAGAAGATAATACGTCTTCTAAATCATCCAATAGTAGTGGTAGTAAAAAGAAATCTTAAGAAAAAGCCTTTATAATGTTCTTTCATTATAAAGGCTTTATTCCTATAATAGTATGTACCCTAAGGATATCTATGAATATATTATTTGTACGCCTTAGTTACATAGGTGATGTTTTGCATGCTACACCTGCTGCGCGGTGGATTAAGGAACAGTATCCTGATGCTAAGTTGCATTGGATTGTAACGCCTAGTATGGCAGAGCTTTTACAGGGTAATCCCTATGTAGATAAAATTATTCCCTGGGAACGGGATATATATGAGGCACATTCTAAAAAACTACATATTCCTACAATGTGGCGCATGTGGTGGGATCTTAAGGCCAAATTAGAGCCTTATAAATTTGATGTAGCCGTTGATGTGCAAGGGCGACTCATAACAGGGCTAGTACTATTAGCTTCAGGAGCCCCCATTAGACTTGGCCTTGGTGGCACAAAAGAGTTGAATTGGCTGTTTACTAACTATAAAACGAAGCCTAGTACAGAACACGTGATTAAACGCTATGTAGAGGTAGCTCAGTTGTTAACAAAGGCTATTACTGAACATGCAAATTTAGATACATCGCTTAACATTGATAAATACGGTATTGAGAGCAGTTGTTCACTAAATGAATCTAATGCTAATATGCTATACCACATGGATTTTCAGGTGCCAACAAATTTACATAGTTGGGCAGAAGAGCAATGGAAGTCGATTGATAATGACGTTTCTTTACATCGAGGCGTGGTAGAAACTCCGTTACGCATTGGGCTGGTATTAGGTACCTCTTGGGCAACGAAAGAGTGGCCTCAGGAAAAATGGTATTCTCTCATTAAATCCCTTCAATATAGAGGAAATTTTGTTTGTTTAGGTGGTCCTAAAGAGGCTACTCAATACAAACCCTTGCTGGACTCTTTGACAGATGAGGGTATTGATAAAATTGTTCTGAATATGTTAGGGAAAACGACACTTCAAGAATTAGGGGCTTTAATTGAAAGTTGTGATGTATTAGTTACTGCAGATACGGGAGCTCTGCATATTGCGTTAGCTTTAAATAAGCCTGTAGTAGCACTCTTTGGCCCTACGGACCCTAAATTATGGGGCCCTCTGACGGGGACCTTTAAGGTGCTCGTAAATGACGAATTAGATTGCTTGGGGTGTCGAAAACGACGTTGTCCTAAGCCAGATCAATATTGTATGTCTGGTATTGATCCAGTACGCGTAAAGAAAGCAATTTTTGAACTGATAGGAGATACACATGGCAAAGTTTAAAATTCAAAAAGGTTTATCCGATGCGGATATGATGAAAAATTTTAAGGATACAGAAAATTTCGAAGATACTATGCTCAATATGGAGCGAGATGCTAAGAAACCAGTAGTTCATCAAAGTCCAAAGCAAAAAGAAGATGCTTTTTACCGTGAGTTCTTAACTGAAAAAGTAGAGACTATGATTGGTAAAATGCTCCTTGATATCAAGATGGAGTATTTTAAAGAAGGGGAAGGGGCTTTCTCTATTCAGGTGAAACGGGAAGGTAAAAATATTGTCCTTGAAACTGCGCCTAAAAAGGTTAAGCCTGAGAAGTAAGCCGTATAATGGAGACTATCAAATTTTAAAGATTAGGTCAGAACCTGTCCGTAAATGGGCAGGTTCTTTTGCATGTTTATGCATTTAAAAATATCGGCTTAGTTATTAATAAAATTGATGAGCTTATAAATATACCGACGTTTATCGAATTACTACATTTATAAATACCGATATATTTTGAAAAGTATTTAATAATAACCAAAAATTATTACGATATAATTTTTAGTTTCTCATTAAAATGAGCAATTACAAAAAAATTAATTTGATTAAACATACATGCTAAACTCTAGTTTCTCTGCAGTTTTTTGTGATATTCATCACGAAAAAATCATCTTAGAATACATGAGATTATGAGTAAATAGCATAATGTGGTTGTTGACAAAGAATTTTATAAGTAGTCTAATATAAGTATGTATTACGATTTTAGCGCGTTTGGCTAGTGTGAGCAGACATCGAAAAAATCGTAAAAAAAATAGGTATGAGATAGTTGTTTAATGAGTGTATAAAGTTACATACACAGACTATTTCGATTTGGAGGATTAACATGGCTAAAAAATTAAGAATTTGCGAAACCGTTCTTCGTGACGGTCATCAATCTATTTTGGCAACACGTATGCGCTACGAACAAATGGAACCAGTGCTCGGCCTTTTAGATGATATTGGTTATGAAGCTCTTGAATGTTGGGGCGGCGCTACTTATGACAGCTGTCTTCGTTTCTTGAATGAAGATCCATGGGAACGCCTTCGCAAATTGAAAGCTAATTTGAAAAATACCCCATTGCAAATGTTGCTTCGCGGTCAAAATTTGTTGGGCTATAAACACTACTCCGACGACGTAGTAGAAGCATTCTGTAATGCGGCTGTAAAAAATGGTATCGACCGTATCCGTATTTTTGACGCATTGAATGACCCACGCAATATGGAAGCTGCTATTAAGTATTCCAAAAAAGCTGGTGCACACGTTCAATCCGCTATGGTATACACAATTTCTCCAGTTCACACAACTGAAAGCTTCTTGAAAGTAGCTGAAACTTTGGTAGAAATGGGTACTGATTCTCTTTGTATCAAAGATATGTCTGGTTTGTTAGGACCTGCTGATGCATATGATTTGGTTTCTACTTTCAAAAAACGTTTTGGCGAATTGCCAATCGACTTGCATAGCCATTTCACTTGCGGTCTTGCTAGTACTACATACTGGGAAGCTGCTAAAGCTGGCGTAGATATTATCGATACTGCTATCTCTCCATTTGCTCATGCAACTAGCCAACCAGCTACTGAAACTATGATTGAAATGTTCAAAGGTACTGAATGGGATCTTGGTCTTGACCTTGATAAATACATTCCATTAGTTGACCACTTCCGTAAAGTAAAACAACAAATCGCAGAAGAATTCAACTTGAAACCAGCTAGTGATGTAATCCCTGCTGTTCGTCGTTACCAAATTCCTGGCGGTATGTTGTCCAATACTCAAAACCAATTGAACGAAATGGGTATGGGTGATCGCTTCTTTGACGTTATGGATGAAATGCCACGCGTTCGTGAAGACTTGGGTTACCCTCCATTGGTAACTCCAACATCCCAAATCGTTGGTACAATGGCTATGATGAACGTTATGATGGGCGACCGTTACAAAATGGTTCCTAACGAAGTTAAAGATCTTGTTCGTGGTAAATATGGTCAATTACCTGGTACAATTTCTGATGAAATTCGTCAAACTATCATTGGTGATGAACAACCTATTACTTGCCGTCCAGCAGATCTTATCGAACCTGAATTGGAAGGTTACCGTCAAGATTTAGCTTCTAAAGGCTACAATGGCATCACTGACGAAGACGTATTGACTTACGCTATGTTCCCAGAAGTTGCTATTAACTTCTTCGATGCAAATCGTCGTTAATCCAAATTTTAAAAGAGGATTCTTAGGAATCCTCTTTTTTTTGACCATATTTAAACTATCCTCATAGAGAAATAGTATAATTCAGTATATATTTTGTTTTATTAAATGAAGAGATTCAATAGTTGTTTCATTTTTTATATTTTAGCTTTTTTATAAACAGTATAGACAAGTTCCTATTAAAAGGGGAGACTAAGGAACTATGAAATATCAGATATTACCAATTTTCATATCGCCATAAGATACATGGGTGCGTGTGAAAATATAATTTTTACGAAAAGTATTAGATATTAAAAGGGTCGAGATACCTTTTAATAATCGGTCAATTATAAACTACGTATGAAAGAATAGTGAAAAATATGTTGGATATTTGCGTGTTTTACTTGCGTTAAGTTATAAAAATAGCGTAAACTATAGAGAGTATCTACTATTTATGATATTGAGGTAATCCTGTGAATTTACAAATACGAATTTGGATATCCAATGTTGTGCTGTTTGTTGTACCTATTTTAATAGCAATTATTTTATTTTTGCTATATTTTACAGGTTTGCGCATATTGGCCAATGCCGGTTACTATTTGCGTATTGAGCAGGAACAACAGTTTAAAAGTGTTAGTCGAATAACTGAAACCATTACCTTTTATGGGTTAGAAAATGATCTAATTAATAGCTTGGTTAAGCCTAGCTATAGCTTACTTGATCCAAAGGAAGTATATGTTGAAGTACTTGATCAAGGAAGTATGGTGTATAACTACGGTAATCCACAAATCTATAGTGCTTCTGCCATTGTTGGTCTTATTGATGTTAACCCTGAATTACAGGGCATCGTATATCAATCCAATAATACTTTCGTTTACGAAATGAGAAAGTACGATGGACGTCATTCCTATGTATACCATATTGCGATTAGGCGTGCTACTCATGGTAGTGATAGCTTAATGGAATCCGTATCTTTCTATATTATCGTAGTTTCCATATTGCTCTTTATTGTTACATTTTTTGCTATTAACCGATTTGTTACACGATTTATCATGATTCACGTTAAGAACATGACAAAGTCGTTAGAAATGGCAAATCGTCAGATTGAAATGGAACAGGAGCAACAAAAAGAGTTACTCGCTGGTATATCCCATGATATACGAACTCCGTTGACGGCTATTAAAGCGTATGCTGAAGGCGTTCGTGACGGTATTGCACCAACGGAAGAGCAACAAAAAAGATACATGGGGATTATTTTGAAACGGGCCAATGATTTAGATTCTATGTTAGAGGAACTATTCCTCATAACAACATTGAATTATAAAAAAGAATCTCGTCCATCTGAGCGAATTGAATTAGGTCAGTTTGTACGTGACTTTGTAGAAGATCATTTAGCTCCGTATCAATCGAAGGGGCTTGAGATTAAGGCCCGTATAGCTACGGAAACACCTTTTATCAATGCTAACCCACAATTGTTACAACGTGTTTTGCAGAATGTGTTGAACAATAGTGCTAAGTATAAAATGACCGATATTGGTCATTGCGTCATAGATGTAACGAGTGATGATGATTTTGTATACTGTGTCATCAGTGATGATGGACCAGGTGTACCGCCAGAATCTCTAGAGCGTCTGATGCGACCATTCTATCGTGTAGATTCGTCTCGTACGAATCCTCAAGAAGGTAGTGGCCTAGGATTGTCGATTATCCGTCGAATTATGGAAATCTTTGAAGGCCGAGTTATGATTGAAAATGTAAGGCCACATGGTCTACGTATTATATTAGAGTTTCCTAAGCAAGGAGAAGAATCATGAGTGAACATATCTTAATTATTGAAGACGATTTGGATATTGCCAATATTGAGCGTGATTATTTAATGGTGGCGGGCTATGATGTAACGATTATGACTAATGGTACAGATGGCATTGAAGCAGCATTAAATACTCCTGTAGACCTTATTATCCTTGATGTTATGTTGCCAGAAATGGATGGCTTTGAAGTTTGTCGTCAAATTCGTGACAAAGTTCGTGTGCCAATCGTTATGGTAACTGCGCGTCTTGATGATATCGACAAAATCCGTGGCTTAGGCGTAGGCGCTGATGATTATATTGAAAAGCCATTCTCTCCATCTGTATTGATTGCGAAGATCAAAGCTATGTTGGCGCAATATAAACGTTTAACAGAGCGCGATGCAATGGAAACAAACGCTATTCAATCCGGTGAAATCCGTCTCGACCCTAAAATGATGAAAGTATGGGTGAATGAAAAAGAAGTTCATCTCAAAAAGAAAGAATTCCAGTTGTTAGAGTTCTTGATGCGTAACCGTGATATTGTATTTAGCAAAGAAGAATTGTATTCTCGTGTATGGGGACTTGACTCCTATGGTGATTATGCAACTGTAGCGGTTCATATTAATCGTTTACGTGAAGAAATTGAGGATAATCCATCCGATAGTAAGCATATTATTACAGTGTGGGGTGTAGGGTATAAATTCGTTTAGTATCGAGAATATGCATTCACATTATACTCACGTTGTTCGTGGCTGTTGATTAGATATGACTTTATAGAGATTTTATTATAGAGATATAATCAAAGGTTTAAGAATTGTTTATATAGTTACTTTGATAGTTTAGATATTCCATGTATACTTATTTAAGTAAGGCTGACTATGACTCTAGATAAGTAATATTTTAACTTCTCTCTCTTAATAAGTTCTCTCTAAAGCTTATCTAGATCACATATACTCTCTCTCAACAGTCCTTACACTCTCAAACTATATGCATAAAGGGCATTTGCTAGCGACGGCTAGTAAATGCCCTTTATGTTTTTTAGATTTTAGATATTTGAATACATTCTATACAGCTTCTTTCAGGATTCTAGGTATTTATCTAGTGGAGGATATACGGTTATAATAATTATACTTTCATAAGAAAAGTTATAAATTGATATCTTGCATTGTAAAAGCAGGCGTACTATAATAGGTTCATCAAAATCAATTTTATAAAATTGATTTTGAGATGATTTGAATTATTGTGAGACGTGGCGTATTTATAAAGTATCATAATTATATGATTTATGATTTGGTTCTTATTTTACCTTTTATAATCATCATTAAGACGTTATGGGTGATGTAGAAGAATATTAAGAAGAATATAAGGAGATCTACATGACATTTTCAAAATATAAGAAAACAGTAATTGCGTGTATTCTTGCTTTGGGTATTGGGGTAGGCGGAGGATACTATTTCTTTGGCAGCCCTGTTAATACGCAACCAACAAACGTGAGAGAACAAACTAAACAGACTAAGCCTATTACTGAAACGCGTAATACCTATGTAGTACAAGCAGCTAAAGAATCTGGGCCAGCTGTAGTAGGGATTACAACACAAGTATTTCAAAAGGATATTTTTAACCGTACTATCTATGCTGGAGAAGGTGTCGGATCTGGTGTGCTTATCGATAATGACGGACATATTATAACAAATAAACATGTGGTAGCGGGGGCTAGAAATGGGGAGGTTACAGTATCATTGTCTGATGGCAGTACGGTGACGGGGACTGTTATAGGTTCAGATTCACAGACGGACTTAGCAGTTGTAAAAATTAAACCTCCAAAAGATATTAAACCTATCAAAATTGGTGACTCTGACTCCTTGCAAGTAGGGGAGCCAGCTATTGCTATTGGCAATCCTTTAGGTCTTGAGTTTAAAGGTTCAGTTACCTCTGGTGTTATTAGTGCCTTAGCACGTACAATTGATGATCAAGGTCAACGATTCCCATTGATTCAAACTGATGCAGCCATTAATCCAGGTAACTCAGGTGGTGCGCTTATTAATGCAGATGGTGAGTTAATTGGTATCAATAGCTCTAAAATCTCTAAAGAGGGAATTGAAGGTATGGGCTTTGCTATTCCAATTAATTCTGCGATGACAATTGTTGATTCTATTATTAAAAATGGTAAGGTCATTCGCCCTTATATTGGGGTGTGGGCTGTAGACCGTCAAACTGCAGCGCGCAATAATGTAACCTATGAAGGTGATGGACTTCTTGTTGTTCAACTTGATCCTAATGGTCCTGCTGCACAAGCTGGTCTCGTAGAAGGGGATACGATTGCACAAATTGATGGTAAAGATATTACTACATTACTTGAATTAAAAGAACAAATTGATGCTAAGAGCCCGGGAGATACAATTTTGGTATCCTATACTCATAACGGCAAAATGAAGAGTACACAGCTTAAATTAGGGGAAGCGTCTTCAAATTAGAATCTAGTAAATAAAACTTAATTAAGTATTCCAATAATGCACTACTTTCTTTTGTAGTGTTAGAAAATCCTCATCTTTTAGATGAGGATTTTTAGTTATAATAGGGTACTTTAATAGATTTTGTATAAAAAATACCATAAATAAGAAAATTTTTTTGAAAAAATTTTTCCCTATAAACGCAGAAATTAACTGTGTTTATAGATTAGAAATAAGAAAAAATATATTAAATTTCAATATTTTTTTACAAGGTACCTTGCGTTCCGAGGTACCTTATGTTATTATATATTTGTCAGTACATGATAGTGACCGTAAGAGAACTTTCACATTGGCAGGCAAGCACAGCCTAAAAGGGAGGAACTATGCAAGTTCAATTAAAAAAAGGTGTTATGGACATGCTGGTGCTAGCATTATTAACACAAAATGATCGCTACGGATACGAAATCGTAAGCACCATTTCAGAATATATTGAAATATCTGAAGGAACGATATATCCATTGTTTAACAGACTGAAAAAAGAAAAGTATGTTGAAACGTATTTAAAGGAGTCTTCTACAGGCCCATCACGGAAATACTATCATATCACGAACGAAGGCCGTGCAGCATATAACAAGATGCGTCAAGAATGGGATGATTTTTCTGTTGTTATCAATATGCTGTTGAAAGGAGTCGATAATAATGAACAAAAATAGCTTTTTGGATGCATTGCGTAATATATTTAAAAAAGCGCGTGTTGCAGATGTGGAGAGTATTATAGAGGTTTATGAAGAGCATTTTGCGGTAGGTTATGAAAAGGGGCTTACCGATAGTGAGATCATTAAATCCTTAGGGACTCCAGAGGAAATATATGCATCCTACGTAGATGCAGGTATCATTACAGACACAATGAATCAAGATGGTAGTGAAAGTAAATCCGTTAATATGCAGGAAATTTATGCACGATTTGATGATTATAAAGAGCGTCTTTTACCTCAATTACCGGGGATGGCTAAAAAAGCATCTAAGACTTTGCTCTCTATTGGAAGTGCCTTATCCTATATTGTAGGTGCTCTTATATTCATTATTACACCGGCTATCTTGTTCTTACTAGGTAGCTCATGGCAACCATTTGAGAATGTTACTGCATTTCCAGTATTGTCCATTGTAACTTTAGTGGCACTTGGTGGTGTAGGTTTATTTGGTGGACTTACATGCGTCTTTGTTGGTACAGAGCTTCGCGGTGTGCGTGAACGTTACTTCCGCAATGTAGATTAAGGAGGTCCTATGAGACGAATTATAATAACAGCGATTTTAACCGTAATTTGTGCTGTTGGGGCATGTACATCTTTTGCCGTTAATGATTTACCTAATTTCGGTGAATGGATGAAAACGAATGAACAACAGTTTAGAAAACCACATAGACATGATGGTCCTAATCAGTATATGGATAAACATATGATGGATGGAAATAATCATATGATGCCTCAAGATGGCATGGGACCAAATAATGGTCAGCATATGCACTCAAATGGTCAAATGCCTCCGCAAGGTCAAATGCCTATGCAAGGCCAACCACCTCAACAACCTAATGGCAATGCACCACAACAACAAACTGATCAAGGTGCACCACAAACTACACAAAACTAACGATACTTTATGAGTCCATTTCTCTCATAAGATATAGAGAACGTGGTCATGAAAGTGCATTCATGGCCACCATAGAGTCACACACTCTATGTGATACATTCGTATCAGAATCTCTCTCTTACACACAATAACTACACACAAACAAAAAGAGCTCCTCAGTGAAGGAGCTCTTTTTGTGTATATTTTATTTGATGTGTTTAGAACCGCGTTCTGTCATAGCTATGCCATCTTTACAAAGAGGGCATTCTTCAGGTTTGTAAGTTGGAACTTTAAGATTAAGTAATGCTTGTACCTTTTCGTGAGGAACACCGAATTCTGCTTTGCCACCAGAACGGTTAACAAGAAGGCCTACACCTACGATTTCACCACCGGATTGGTTTACAACATTTACTACTTCTTGTACAGAACCACCAGTAGTTACGATGTCTTCAACGATAAGTACCCTTGTGCCTGGCTCGATTTTAAAGCCACGACGCAATGTCATAACGCCTTTTTCGCGTTCTGTGAAGATAGCACGAGTGCCAAGCGCTTTACCTACTTCATGAGCAAGTAAGATGCCGCCAGTCATAGGTCCAATAACAAGTTCCACATTTTGATCGCGGAAGCGTTCAGCTAATTCTTTACAAAGTTTTTCAGTATATTTAGGATGTTGCAATACGTTGAATTTTTCAACGTACATTGGGCTGTGGAGACCAGATGTCAAAAGGAAGTGACCTTCTAAAATAGCTTGAGTGTCGATAAGTAATTGTTTTACTTCTTGTTCTGTCATCATTTGGATACCTTCTCCATTTCTTCAATAATTAAACGAACCGCTTCACGAGGGTTTTCGGCTTGTGTAATAGGTCGACCGATAACAAGGCGAGATGCTCCATCTTGTAGTGCACTAGCTGGTGTAGCAACCCGTTTTTGGTCGTCTGTTGTTGCAAAGGAAGGGCGAATACCAGGGGTAACGATGAGGAAGTCATCGCCACATGCTTCACGAATCATTTTGGCTTCTAATGCGGAACATACAACACCATCCATACCACAGTCTTTAGCGAGTTTTGCAAGGCGAATGACTTGGTCGGAAATTGGTAGCTGACCACCAATAGCAGTCCAAGATTCATCGTCAAAGCTAGTTAATGCGGTGATGGCTAATAATTTTGGGCGTTCTACGCCTAGTTCTTTGCCACTCTCACGAGCTGCCTCAACAGCAGCTTTCATCATGACAGGACCACCTTGACCATGTAAAGTAATTAAACTAGCGCCGAGACGTGTTAAGGAAGCTACGCCATGGGCTACGGTATTTGGAATGTCGTGCAATTTCAAATCAAGAAATACTTGTTTGTTTTGCTCCTGTAAAAAACGAATTGTTTTTGCTCCTTCGGCGTAGAATAGCTCCATGCCGACCTTGTAAAAGCTAACCGAATCACCGAGGGATAATACGATTTCTTTCACTGCATCCATCGTGGATACGTCAAGAGCAACGATTAATCTGTCATCTGCCATGTTGCAACCTCCATACTACATACATATCTAAATAATTTTCACATACTGAGGGTCTATCTGTCAATTAAAATTGGTATGAATGAGGTGATTATTGCTCACCTTTGAACAGTAGATTATAGTCTATTTCATGCTATAATAAGTAGAGTAAATGAATATAATTCTTATATATAGATTTTGAAAGGAGTCCTATGTTAGATTTTGTTGCATTAGACTTTGAAACAGCAAATAAATTTAAAAATAGTGCGTGCTCCTTGGCGGTTATTACCGTAAAGGACGGACAAATTACCAAAAAAGCATATAGCCTCATCAAGCCTCCGTTTATGAGTTTTGATGATGAATGTATTGAAATTCATGGTATCCAACCGAAGGATGTTCTTCATGAAAAGACCTTTGATCAGTTGTGGAATGCCATTTATGAAAACCATTTAAAAGGTAATATTATGGTGGCTCACAATGCGAAATTCGATATGAACGTATTGCGTGCTACTTTAGATTATTATAAAATCCCTTGGCCAGAACTAGATTATGCATGTACAGTTAAACTTTCACGTGCGGTATGGCCTGATTTGGTTAATCATAAGTTGAATACAATGGCCGCATATATTGGAGTTGAGTTTAAACATCACTATGCACTGGATGATGCAGAGACTTGTGCAAAGGTTGTATTAGAAGCTGCTAAGTTGAAAGGCGTTAATAGTTTACCAGATTTATTAAAGGCTACAGGTGTACCATTAGAACCATTCATTGATGATAAAAATCGCTCTGCTCAAGATGCATTACATAAAGAGCCAGAACCAGAGCAAATGTCGTTCTTTTAGTAAGGAGAGGTACTATGTTGGGTAAAGAATTATTAGCTTATGTAGATCATACATTATTGCGTCCTACAGCTACATGGGATGATATTAAAGAAGTTTGTGAGGATGGTATAAGGTATAAAACCGCATCTGTTTGTATTCCTCCAGATTTTGTAGCATCTGCCCATGAAGCATATCCAGAACTTAACATATGTACCGTTATCGGCTTCCCTTTAGGATATGAAACAACAGAGGTAAAGGTGGCAGAAACGAAACAGGCTATTGAAGAGGGCGCTTCTGAAATTGATATGGTTATTAATCTTGGAGATGTAAAGCAAGGTGATTTTGAAGCGGTAACTAGCGAAATTGAGGCGCTTAAGAAGGCTTGTGGTGATAAAATTTTAAAAGTTATTATCGAAACTTGTTATCTTACAGATTCTGAAAAGGTGGCGCTTTGTAAATGTATTACAAATGGTGGCGCAGACTATATTAAAACATCTACTGGATTTGGTAGCGGCGGTGCAAGCCTTGAAGATATTAGACTCTTTAAAAAGCATATTGGTCCTAATGTACAGATTAAGGCTGCAGGTGGTATTCGCTCTATTACGGATATGAAAGCCTATATTGCAGAAGGTTGTAGCCGAATTGGAGCCAGTGCAGCTGTAGAGTTACTAAAGAATCACTTGAACGAAGAAGTATAATAGAAAACCACCTAGGCTATGCTTAGGTGGTTTCTTAGAATGGCGGTGTAACTATGCGTATGTATGATATTATTCTGAAGAAAAGGGCGAACTTGCCGTTAACAGATGAGGAAATCCGCTTTGTCATAGATGGTTATGTAAAGGGGGAAATCCCTGATTACCAAGTGAGTGCGCTCTTGATGACCATAGTTTTTAATGGTATGAATGCTCGCGAACTAGGAACTTTGACCTTGGCTATGGCTCAATCAGGTAATATGGTAGACTTGTCAAATATTGATGGGATTACCGTAGATAAACATAGTACAGGCGGCGTGGGAGATAAGACAACACTTATTATTGCACCTCTCGTAGCCGCTTCTGGCGGCAAGGTGGCTAAGATGTCTGGACGTGGACTTGGTCATACAGGTGGCACTATTGATAAGATGGAATCTATTCCAAATTTAAAGGTATCTTTAGAGCAAGATGCTTTTATCAATCAAGTTAATAAAATTGGTCTTGCTGTTATTGGTCAGTCGGAAGGGCTTGCACCTGCTGATAAAAAGCTATATGCTTTGCGCGATGTGACGGGAACTGTTGATAGTATCCCTCTTATTGCATCCTCTGTTATGAGCAAAAAATTGGCTTCTGGTGCTCAAGCAATTTTGTTAGATGTAAAGGTTGGCAGTGGTGCCTTTATGAAAAACATAGAGGATGCTCGTGAATTGGCTAAAGCAATGGTAGATATTGGAAAGGAAAATGGCCGTTCAGTTAAGGCTATTTTGACGGATATGGATCGACCGCTAGGCCATGCTATTGGAAATGCGTTGGAGATTCGCGAGGTTATTGATACGTTGAAAGGTCATGGTCCAGAAGATTTAACGCATGAATGTATTATCATGGCTGCCCACATGCTCGTATTGAGTCATATATGCGACTATGAAACGGCTCTCAGTCGTGTGCAAGAGGCACTCGACTCTGGTGCCGCATTAGAACGATTGCGTATGATGATTGATGCTCAAGATGGCGACAGCCGAGTTATTGATGATGAAAGCCTATTAGCCATTGGCAAATTCACCTATGATGTTACAGCGCCTCAAGACGGTTATATTACCCATATGAATACAGAACAATGCGGGATTGCATCCGTTATGCTTGGAGCCGGTCGCACTGTTAAGGATGGTCCTATCGATTATAGTGCGGGCATCTTGATGCACAAGAAAACAGGCGACTCAGTTACAGTAGGTGAATGTATAGCTACCTTGTATGCTTCTGATGAGAGCTTGCTTTCTAATGCTGCAAAGACATATTTAGAGGCGATTACCTTTGGCGAAACTGCACCAATCATGGCGGATACGATTCTTGATATAGTGGAATGAGGAGATCCATATGATAGAAAAGGAAACTCATATGACAGAACAGGAAATTCAAAACCTTATAGATCGCGCCATCGTTGCTCGTGAGAAAACTTATAGTCCGTATTCCCATTTTGGCGTAGGTGCAGCTATTCTCTGTGAGGATGGGACTATTTATGAAGGGTGTAACATAGAAAATGCTTCTTATGGCTTAACGAACTGTGCAGAACGAACCGCTATATTTAAAGCTGTATCAGAAGGGCATACAAATTTTAAGGCTCTTGCCGTAGTTGCTGATACGGAAGGGCCTTGTGCACCATGTGGTGCTTGTCGTCAGGTAATGGGAGAGTTTAACATTCCTATTATCATTATGAGAAACATGAAGGGCAATATAAAAGTAGTATCTATTGAAGCGTTATTACCATTTAGTTTTTCATCTAACGATGTAATTGATAGATAGTACCTTCAGCATTGGAATATTCCAAAGACAAATTATCTGAATTTATTGTATCTGGAAGATAATCGTCACCATAAACGAGTAGATATATTTTTTTATTTGTTGGTAAGTCATTTATAGATATAAACGGCATGACATCTTTAGCGTTCCAAGAAATAGTAGTTGGATCAGGGGCTACTTCATTGGGGCCGAGTAATTGATATACTTCATGACCGCTATAGTAAGTAGGTGAAACGCGATATCTACCACTACCTTGTACAAGAATGGAGTCATCACTAATAGACTGGCTAATAAATTGGCTAATACTAGGTGTTGAGGCTTTCTTCATTTGTGGTACTGCTACTGCAAATGTAAGCACTATATAAGCAATACCCATAACGAATGCCGTTTTATAAATTAAGTTGATACGTTTGTAGCACATAACAGCTATTAATATAGTTAACGGTGTTAAAGCAGGAAAACTATAGGTGGAGTACTTAGTTGCCATACAAGTGAAAAATAGGATAACTATACCAGCCCAGACAGCTAAAAAGCTATGGAATGGAATATTGGTAAACCAATTCTTGCGATTACTATAAATTGACTTCGGTAATATAATGGACCAAGGTAATAATGCTATGATTGTTATAGGAATGTAATAGTACCAAACATTGAATCTTGGATGCTCAGACACTGTAGCACGAAGCCAATTATGGACACCTAGAAAGACATTGATAAAGTCATTTCCATGGGTGATATACATATAATAATACCAACTACCACCGAGGCTTAGAAATAGTAACAGTCCAGGTATAATCTGTAGACTAAATAATTCTCGAATATCTCGTCTGATTGCAAGGTAAACTAATATGATGAGACCTGGCAATAGGAATCCAATTGGACCTTTAGTCAATACGGCAAAAGCAGATGCTATATAGGCTAATAGATAGTAACGTTTATAACCTCGTTGACCTGTTTTATGATGTATGTATCCTATGTAAAAGCTCATTAAGGTAGCATTAAAGTATAGTCCTAGGGTCATATCTGTTATAAGAGATTTTGCGATAATCCAATATTCTGCTGACACGGATACGATAATGGCGCTCACAAGAGCAATAACGTGGTTTGTTTGTGCTTTTACAAAGCGATAGATTAGAAAAATATTGCAGAGAGCTAAAAGGCTAGAAAAGAATCTAGCGCCAAAGTTTGTAATGCCAAATAGTTTGAAACCAACAATGAGTTCCCAATAATAAAATATAGGCTTATCATACCAATAATGACCAAAAATTTGTGGAGATAAATAGTTTTTGGTTAGAAGCATTTCTTTTGCGGTTAGCGCATAATTAGACTCTGCAGGATCCGTAATACTAAGATATGCATTTCCAATAAAATAAATGATGGCAGAGAAGATAAGGACTATCAAAATATGATAGTTCTTATTTTTTAAGACATACTTCATAGCCTTAACCTTTCATGCTAAATTGTTTACTCAATGGTTGGTTTGCTTTTTTTATAAGATATAGGCTTAGTTTTGTATTTATGAGTAATCGGAAAATATTATATTTAGGGTGATTTAATAGCGTATCAATCTTAGAAGATAAATAGTTTTGATAGACTTTAAATAACAAATATGTGATGAGGATACCCATGATAACGTCTAGAGGATAATGATGACCAACAAAGACTTTCGCAAAACCTGTTAAAATGGTTCCACTTAGTAGAATAGAACCTAGTCTCTTATAAACTGCTAAAATTGGTAATGAAATAGCAGTCATTGCCATAGCATGGGTGCTAGGAAAACTAGAATCAGCTACATGAGGAATAAGTAGATTTACTGTGTGTGTGACGAATGGTCTTGGTTCTTGCACTATGAAACCAATGATACTATGAGCTATCATGGTAATACCAAGAAATGCGATAGTATGTATGCAGGTTTTTATAAGTCTTTTATCTTTAAAATAGAGGCCTAATCCAGATAAGAGTATCAGTAATAAAGCAAAGACTATTGAAAGGTATTTTACAATGTATATCATACTTGTATCTAGCCACGTATATGTACCTGCTAGGCTGTTGATAAGTTGAAAGATTTCGTAATTCATATATATCTCCTTTTTATTTGATGACTTTCTTGTATGAATACATCATAAAGGAGAAATATTACGAAAATATAACGATGAAATTACATCTTCTAAAAGATTGATTTCTATATCATGACAGATAAGATATAGGTTTGTATAATAGTTAAAAAGGAGGTATCTATGCTTTTTAACTGGTTTAATAGCTTAGGCGTACGGCGAAAGATGATAATTAGTAATTTATTAATTATTATCATACCTTTTATTGTTTTACTTACCGCCTTATCTATAGTATGGGGGGTTATTCGTTATACTAATCCTGTAAATCATCGTCAGTGGATGATGCTAGCGCCTAGTACAATTCAGTCTCAAGTATTTCAATTGGGGTTAGAACAAATAAATAAGAAACTTTCAAAAGAGTCTACATCAATAAGTGATATTTTGGATAGTAGTGCTGTTTTAGAAGCACAAGGCTTAGATATAGTCATTCTCAAAGATAATAAAATAGTTTATGCTACGCCAGATATAGAGCCTAATATAATGTTATCGAACGTTAAAAATATGATAAATGGCTTAGAGTCTAATCATTATTTGAACTGGGAAGGCAACCAATTTACCTATGTGAATTCCTATGATATGGGACTTACAGTGTATGGTGCTGGTAGAATCCCATTTATGACTAAAAGTATGGGGCCAGAATCAACGGATAAGAAAATGGTGGAAGGCGCTTTTGGTATAGGTATTTTAATGATAATAGCTATTATCATTGGTATAGGCCTATATATATCCAATCGATTAGGTGAGTATATTTTGAGACCTGTCATAGATTTGAAGCAAGCTGCTGATGATCTCAAAAATGGGATAGTGCCAAAAAGAATTGCTGTAAGAAATCACGATGAATTAGGGGTTACTTGTGAGGCATTTAATAATATGCAGGAATCATTGCTTAAAGCCCGTCAAGAGCAAGACCTTTATGAAGAGCGTAGGCGCGAAATGATAGCAGGGGTTTGTCATGATATTTCAACACCACTTACATCGGTAAAGGGGTATGCTAGTGGTATTATTGAAGGTATTGCAAATACAGAAGAGAAGCAAGCACGCTATGTGCAGCGGATTTATGATATGGCGGGGCGTATTGAACATTTAGTTAATATGCTATCGGACTTTTCGCAACTAGAGTTAAAACAAATTCACTACAATCGAGATACATATGCATTAGATGATTTAATTCGAGAGTATATTAGAGAGCGACATTTAAATAATCATGAACTTATCGTTTTACATGAATCGTATAGTGCCGAAGATAGTTTAATAGTAATTGATCGGATACAGTTTTATCGTGTTTTGGATAATCTTGTATCCAATAGTATAAAGTATAGACGTGGCGAATCTGTATCTATTGATATATCTACAGCTAAGATAGATAATGGCTGTAAACTGACTTTTTCAGATGATGGGAAAGGTGTTCCTACAGAAATGTTAAATCGTTTGTTTGATATTTTTTTCCGTACTGATGAAGCACGTACAGAGGTAGCTAATGGTAATGGCATTGGGCTGGCTATTGTAAAACAAATCGTTGAAGATATGAATGGTTCTATTCATGCTGAACATAATGATAGTGGACCTGGACTATCCATTGTGATGGAGTTTCCTTTGGATAAGGAGTAAAAGTATGGGAAAAGTTTTAATTATTGAAGATGATATGGGTATCTATGAGTTAGAGCGAGATTATTTAGAAATCGAAGGCTATGAAGTAGACATTCAAACTAATGGCGTTGATGGGTTAAAGGCAGCCCTTGATTATGAATATGACTTAATTATTCTTGACATTATGATTCCTAAAAAGGATGGATTCTCTGTGTGTCGAGATATTCGTAAGGAAAAAGAAATACCTATTATTATGGTCAGTGCTAAACGTGAAGATATTGATAAAATTCGGGGGCTAGGACTTGGTGCTGATGATTATATGATTAAACCTTTTAGTCCGGCAGAGCTTGTAGCACGTGTTAAATCACACATTCAGCGTTATAATCGCATCCGTAATAGTCTAAGCCCTACAGTTGTGTTGGACGCAAAAATTACTGCAGGTAGCTTAGAGATATTGCTTGATTCTCATCAAGTTTTTTTAGGTGGTACTGAGGTGAATTTGACTCCACGTGAATATGACATTTTAGTTCTTCTTGCATCTAGCCCTAATCGTGTATTTACAAAAGAAGAAGTATTTGAAAGTATCTGGGGGATAGACTCTTTAGGAGAAACTTCAACAATTATGGTTCATATAAATAGATTAAGAGCTAAAATTGATAAACAATTCCAAAATGAAGAGTATATTGATACTGTTTGGGGTGTAGGGTATCGTTTCCATAAATGGGATAATTATATAAAACAATAGTATAAAATATTAAATAAAAAAGGCGTCTCAATGGAGACACCTTTAAACATAATTTTGACTAGTATATGAAGAAAGCTAGCCGCTGAGGCTAGCTTTTTGATGCTTAGAATGCAGGAACAATAGCACCTTGGTATTTTTCTTGGATGAATTTGATAATTTCAGGACTATGAAGTGCAGCCATCAATTTTTTGATGCGAGGGTCATTTTCATTGCCTTTAAGTACAGTTACGATATTTACGTAAGGGGAATCGTTATTTTCAATTGCCAATGCATCTTTGCCAGGGTTAAGACCTGCGTTTAATGCAAAGTTAGTGTTGATAGCGGCTAAGGCTACATCGTCAAGGGAACGAGGTACTTGTGCTGCTTCTAATTCTACGAATTGATATTCGTTAGGGTTCGCAGTAATATCTTGCACTGTAGATAAGATGTTTGTAGAGTCTTTTAATGTAATTAGACCTTGTTTTTGTAATAACAATAATGCACGGCCACCGTTTGTAGGGTCATTAGGAATAGCGATTTTAGCGCCTTTTGGAAGATCTTTCAAATCTTTGATTTTACGGGAGTATAAACCCATTGGCTCAAGATGAACACCACCGGCAGATACTAAGTCAAGTTTGTGAGCTTTTGCGAATTCCTCCATGTAAGGTACGTGTTGGAAGAAGTTGGCATCAATCTCTTTGTCCCCTAAAGCCAAGTTAGGTGTGTTGTAATCAGTAAATTCTGTGATTTTTAATTCGATACCATCTTTTGCTAAGATTGGTTTAACTTGTTCCAAAATTTCTGCGTGAGGTACTGCTGTTGCCCCAATTTTTAATACTTGTTTGCCATCGCTAGCAGCTTGTTTGTTGTCGTTACCACAGCCTGCGATTAATAAAGCGCCGCCAAGGATGACAGTAGCTGCTAATGCTAAAAATTTTCTCATTAGACACACTCCTTATACAATAATTACATATAAAATATTAAATCTATAGTACTAAATAATTTCCTATCTATCAAGAAGGAATTATTATAGGTTCTCCATAACTAAAAACTATGGAGAACCTATAATATAAGTATGTTCATTTTTTAAATTAATTTGCCCATGATAAGTCCAATCGCCCACATTAGTTGATAAATCATAGCGGCTCCAGCGGTAGTACCCATAGCCTTATCTAATTGGAACTCATCTGTATTGGTAGATAATGTATGAATTGTTTTGAAAGCTAGTGGTGCTGCAAGGAACGCTAATAAGGCGAACCATGTCATATGGCCTACTATAATCCAAGCAATGATCCAAATAAAATTGAAAATATATGAGATACTCATTAAGCTGAGTGCTCTTTCACGACCAAGCACGATTGGCAACGTGTGACGTCCATGGCTTTCATCATTACGAATATCTCGGATATTATTCGTCAACATGATGGAACCAACTAGCAATGTAGATGGAATTGCAGGAATTAACAGGGCTAAGGATAATTCTCGTATCCAGGCATAGCCTGTAATGAGTACGATAGCAAAACCCATGGCGATACCAGAGGAAATTTCCCCAAATGGTGTTCGAGAAATTGGTTTTGGACCGCCAGAGTAAAGGAAACTAATTAGAATACATAAGAAGCCTACCGGGATGTAGTACCAAGTTATAGTAGCAGATAAATAAAGACCAATAATAATGGGTACAAACATGAGTACTTTAATCATCGTTATAATGAGCTCTGGTGTTATAACGCCACGTGTGATAGAACCAGCATTACCTACCTTTTGACCAGCATCGAGTCCAGATTTAAAGTCTTTATATTCATTCCATAAATTAGCTACAATTTGGGCTGTTACAACAGCTAAAAATATGAGCATTGTATGGAAAATGGCAAGACCTGTACCCTGAGCAGCACCAAATGCATAATAACTAAAGGCGGCACCTAAAATGGTAGGCCCCAATGTAGCAGCTAATGTGCGAGGCCTAGTGAGGGGAATTAATTCTTGTATCATGTTAAAAGCACACCGAGTGTGCACTCCTTTCCATTTCTCATACATATATCATCTTTACATGTCTATTTATGTATTGTATAGCAGAAAGGTAAGCTTGTAAATTATACTATACAGTTATATATGTCGATATAGTATAATAATTAATATATGCAGTATAGATTCTCCTTTAAACTCTTAATATATACTGCACAGATTATCTAACAATCTATACATAGTGTATTGTTAAAAAGGTGAGGTGTCTTATGAGAACTCTCAATAAAAAGTTGATGACATTGGCTTGTGCCACCTGTTTAACTGTGGGTATGGGGGCAGTGGCATGTGCTGATACGGTAGATTTAGGTTATGGTATGTACGGCACAACTTCCCCAACTGTGAAAGCTGTAGAAGTTATGCATATTTCTACTGATACAAGATTGCGTAATCAAGAACAAGATAAATTTCTTAAAGTAGCAAATAAATCTGCTGTTGATACTATTAATAATGTTGTGAAAGCACAGACTGGTGTAGCTGTTGAACCAGTGAAGGGGGACTTTCTTGATGGTTACTCCTTCTATCAATTGCAAGGTACTGATAAACAAGGACATCATATAGGTGGTTTAATTGTTATTAACTATTCTAAAAATGCAATTGATCAAGTTATAGGTATGAATAAGACTATTTTAGAGAAGGGGGCAGATGCGGAAAAAGCCGCATTAAAGCATTCTATCTCTAAATATGTAGAATCTTACTCTAAAGAGACGGCCCAACAACAATTACAAGGCCTGAAGAGCAATACTATTGAAGGTGCTAAATTAGCTAAAGATCTAAAAACGATAAATGATAAGTTACCTTCTCAAATTATAGGTGTCTTTGATAAAATGCTTGCCACAGATAAGAAATCATCTCCTAAAAGTATAGAAGAGATCCGTTCTTATGTAGACTTTATGGCAAAACAAGTAAGCCTAGATGCAACGCATGTGGCCTATAAACCTGTTCAAACACGCTATGGTACAGCTGTGACAGGCGATTTACGCGGTAGTCTAAAATATGATGGCTTTAGAAATACTTATTCCTTAATTGGTTATGCTGTTCCTACAGATAAAGGTGTATCTTTACAGATTTTAATGTCTGATGACTCTAGCTATGATTATTGGGCTAATGAGTTGAATCATATGTATCAAACACAATCTCTCAAGGGAGGTAAATAATATGAAATCTTTGAAAGTATTGGCTTGTGCAGCTTGCCTAATGGGTACTGTATCTGGCGTAGGTTTTGCTAAGGATGTACAAACAATTGCAGGATCCATGGTAGTGCCTAATAATGTAAATATTGTTTCTGCGTCTAAAACAAATACACGTGATTTTGTAGAGAAACAAATGCAACAGAATCCCTCAAAATCTACGATGGCGAATATGATGGCAAAGGAATTTTTCCAAAACTTTGGTACTAATTTTGATATATACCAATTGCAAGGGGCAGATAAAACTGGTCAAAAAGATGCATTCGTAGTGGCTGTAGATGTTAAACAAATAGCGCAACAAGTGGCTAAAGAAAAGGCTAATGACCCTATGTTTATAGCGGCAATGGCCGCTCTTGATAAAGGTCAAATTGATCCTGTAACAGAGCAACTTCTATTAGGAACAATAAATAAACAGATTCCCACTAGCACAACAGTAGTTCCTTTGAATGGACCTATTAATGTGTCTAGTCGTGATTCCCAAAAAGCAACGATTATGCCTAAAACACTTAAAACTCTAACCGTAGAAAATGCAGAACAAGTACATCCGGTGGCTGGTACAAAATATCAAACATATGCAGCAAGCTCTCGCTTGTTATATGCAGATGGAAATGTACAAACTCCACTCTATGCAAATGCTGCATTTGTGTTGAAGCCAGGAAAACCAGTGTTGTATGTAGGTATAACAACTGATGTACAACGTGATTATTTCAAACCAATATTTGATAATGCATTTAAATCAATTAAATAATTGGTTATATACGTACTTTTGTGTAATATGTGATATATTGAGGTAAGTCATATATATCGAGGCATCAACATGAGTTTCGCACCTTAAATATAGTCATATTAATTTATATTTATTTATAAAAGGAGATTTATCATGAAAACAATTTCTACAGACAAAGCACCAGCAGCAGTAGGCCCTTACTCTCAAGCTAAAGTTATTGGCGGTTTATTATTTGCTTCTGGTCAAATTCCACTCAATCCTGCAACTGGTACAGTTGTTGAAGGGGGCATTGTAGAGCAAACTGAACAAGTATGCAAAAATATTGAAGCCGTATTGACTGAAGCTGGTACAGACTTTTCCAAGGTTGTTAAAACAACTTGCTTCTTAGCTGATATTGGTGATTTCAAAGCATTTAATGAAGTGTATGCTAAATATTTCACTTCTAAACCAGCTCGTTCATGTGTAGCAGTAAAAGACCTTCCATTAGGCGTTATTGTAGAAGTGGAAATTATTGCGGAAGTATAAGATGGATTATGTTTCTTTGTTACAGTCAGAGATGCGTCCTGCCTTCGGTTGTACTGAGCCAATTGCATTGGCTTATGCGGCTGCGAAGGCAGTCTCTGTTTTAGATGAATTTCCTAACCGTATTCACGCAAGATGCAGCGCGAATATTATTAAAAATGTAAAATCTGTAGTCATTCCAAATTCTGGGGGACGAAAAGGACTAACGGCGGCTGCTACACTGGGTGCTATTGTAGGTCATCCAGAGCGTGAACTAGAGGTATTAGAATCTGCTACAGACGAAGATCGCAAATGGCTTGGCACATTGCTTGATGCTAACTTCTGTAACGTTTCACTTGCTGAAGGCGTAGATAATCTATATATAGAAATCACTGCAGAAACAGATGAACATACAGCGGTTGTTCGCATTGAAAATGACCATACGAATGTAACATATGTATCAGTAGATGGCGAGATTGTCTCTGAAACAGTCAATGAAATTAAGAAAGCGGCCAAAACAGAATATGCCATGACCTTCGATAGCATTTACGAATTTGCTTTAACAGGTGATATTTCTGGTATCCTACCTCAAATTAAACAGCAAGTTGAGTATAATACTGCAATTTCTAAGGAAGGTCTGTCCAATGATTATGGATCTAATATTGGACAATTGTTATTGTTAGATGAAGAAAATCCATCTCTCGAAACGAAATGTAAGGCTCGTGCCGCAGCTGGCTCTGATGCGCGTATGAGTGGCTGCCCATTGCCTGTTGTTATTTGCTCTGGCTCTGGTAATCAAGGTTTAACCGTGTCTGTACCAATCATTACGACTGCCGAGGAACTTGGTAAAAGTGAAGATGAATTGTATCGCGCTCTCGTCTTTGCTAACTTGCTAACGCTTTACGTTAAATCTGGTATTGGTAAATTGTCTGCATACTGTGGCGTTGTATCTGCCGGTGTGGTAAGTGTAGCAGGTATTGCCTTCTTGAAGGGTGATAGTAAAGATATAATCGAGAACACTCTTGTAAATGGTCTTGCAAGTTTATCTGGTATCGTATGTGATGGTGCGAAACCATCCTGTGCAGGTAAAATTGCAATTTCCCTTGATGGCGCCTTTATGGGATATAAACAAGCTCGCCTTAACAAAAACTACCAAAAAGGCGATGGACTTGTAGCATACTCCGTTGATGAAACTATCCGCAGTATTGGTGCTGTGGCACAAGGCATGAAAGAAACGGATGTAGTTATATTGAATGAAATGCTAAAACACTAAACTGCAAGTGACGTGGTTAGCTGAATATAAAAAGAACCCTTCGTTGGTCTGTACCTTCAAAAATTGTGTCCAATTTTTGGGGTACAGTTCACGTGAAGGGTTCTTTTTTGTTTATTGTAGTTTTTTAGGATCTTTAAGTATCAATGAAGCCCCAAGACCCACTACTAGGAATGGTACGAGTGTCATCATAGCGGCAGGTAAAGAATAGGTATCCGCAAGGTTACCTACTACAGGTGCGATGATACCGCCGATAGTTTGGCTCACCCCAAGGGTAATACCGGACGCAAAGCCGATGCTTTTAGCAAGGTAGGTTTGGCCTAGTACGATAACGGGGCTGTAGCTAAGAGCTTTAGCAGCGCCAATCATGAGTAGTAACATATAGGCTATAGGCATCATGATAACAGGGGAGAAGGTTGGCACTTCTGTTAATAGGAACATGGCTGGCAACCAAATCAATAGGGATAGTCTAATGATTTTAATGGGACCATATTTGTCGCCTAATAGACCGCCAATATATGTCATGAAGATACCGATACTAAAGAATATGGTTAATGCAAAGCTACCTTGCTCTGGGCTAGTGCCGAGTTCACGAGTCCAGAAGATAGGAATAAATGCATTGATAACGCGGAAGTTTACTGATTGGCTTAGGATGATAATAAACAAGATACCAAAGTATTTCCAGTAATTTTTTAGCGGCTTAGCCACTAGTGTAGGGTTTTCCATAGCTACCGCTTGGTCGATAGTGCGTGCTTGAGTTACTATGCGCGGCATGAGGACGAATAAAACTGTTGAGATGATAAGACCCACTATGGTAAAAGCTGCCAGTCCATGAGGTCCTACTGTATAGGCAATAGAGCCCGCAAAGAGTGGACCGATGGCAAAACCAGAGCTACCACCGATGGCGAAGGTACCCATGGCTTTACCTTTTTTACCACCTCCCAGGCGATTCATGATTTTCGCTCCTTCAGGGTGGAAGATAGAGGAGCCTACACCAGCTAAGGTAGCACAAACAAGCAAGCTTTCATAAGAGGTTACAAAACCCATGGCACCTGTGCTACAAGCTGAGAGCAGAACACCTAAGGCGATTAGCCGTGGCTGATTGATCTTGTCAGAGACATAACCTAATAATGGCTGTAACAATGAAGATAATGCTGTATTGGCTAATATGAGAAAGCCTGCTTGCTCTAAACTAAGTCCATAAGTGTAGATAAATAATGGCAAGAGGGCAGGTAATACACTTTGACAGGAGTCGTTAATCATATGACTCACCGTAATGAGATAAGGGTAATATTTTTTCATAGTAGTGGTCCCTTCGCAAAAAAGCGCTAACCATGGTTAGCGCTTTATATATTTTATATGGCAGAGGAGGAGGGATTTGAACCCCCGCGCCGGTTGCCCGACCTACCGCATTTCGAGTGCGGACCCTTCAGCCTCTTGGGTACTCCTCCGTGTTTTACGGCGCTCTTTAAAAAAGTCTTTCATGATTTGACTACATTCATCACCAAGGACCCCCGATGCTAATTCGGGTTCATGATTTAAACCAGGGTGAGAGAGTACATTGAAAAGAGACTCTACAGCGCCTCCTTTGTAATCACTTGCACCATATACAACACGGTCAATACGACTGTTGATGATGGCTCCAGCGCACATCGGACACGGCTCTATCGTAACATACAGGGTACAACCAGTCAACCGCCAACGCTTGAGTACATCGCATGCTTCGCGGATGACGAGCACCTCTGCATGAGCCGTTGCATCGTGATCTAATTCGCGGCGATTATGGTGGCGTGAAATGATTGTATTGTTTTGAACTAAAATGGCGCCGATAGGAATTTCTCCTAGAGCATAAGCTTTGTGGGCCTCCTTTAGGGCAAAACCCATAAAATATTCATCACGGCTACGCTCATCCATATTTTTAATCTCTATAGGTGTAATGTTCTTTGTCAT

Protein sequences of DBSCAN-SWA_3

>NZ_CP019721|1063084:1139493|1096813_1097710_+|WP_077708165.1|DBSCAN-SWA
MAEWSNATMTDVGANLQAKVNAGKTKLTFTKIKVGSGVNSTNPLALTDVISSKWETTNFVVKLEGKIVSVDTVITNTGIHEAFRMSEIGLFAQDPDKGEILYAYLTDPEPDRMPAESGSVVVSQELTIGMVFSNTGNVSLTVNMGALVTREQLTEAVKQHNTDISSHPAITAMIAKILGATNWQENPVATLKDIKNLIGQGAIVASKLDANAGFVKFANGFTIQWGVGGQDNVTKTEVRFPIKFTTLFMANAIDAYWSGSDTPRYFANSVSESNATKAVFSASDRYAASYYWFALGII
>NZ_CP019721|1063084:1139493|1087373_1087601_+|WP_077708155.1|DBSCAN-SWA
MNPVVYVGPSFRSSRLNQFMVFSDGAPLPEAEDPIFMHLFVPLDELNQAMIDVRTQGTQLNVFYVNALKNYKGVK
>NZ_CP019721|1063084:1139493|1081676_1083284_+|WP_077708148.1|portal|DBSCAN-SWA
MARKNNKFSAKIGTPRAKNSGYSEGGASHNNKSLKGYNPRKLGYKADIGANLSTLRDRSADLAINTPVGTAAINTSTTHTVGAGLNVFPRPKFQILGISAEEARAWARKVRAEFDLWAESKDCDIYRKNNLYDMQSIAYQGYLTDGDSFAVFRRKPTTPDMPYTLRLQLIEGNRVSNPLTDSTYVTGDPTGVEALNPDNGNRILNGVEIDTDGAIVAYWVSNQVPGEPITSMLTTWARVEAYGKRTSIPNVLQISNDTRPEQYRGVPYLAPVIETLKQVYRYTNAELTSAIIKSYFALFFTEAVTNSGSLNDMLADNGVDDPTEPVVDVSEYNLGPGTLNALPKGVDVKSVDASNAQSTFEVFSTQLIKQVGAALNQPYEVLMKNFNSSYSASRAAMLQAWEEYKLRRKWFARDFCQPIYEIWLMEAVANGRIEAPGFFDDPLIRKAWCNADWFGPTMSILDPVKDMNGSTLRIENGVSTREREAAEMTGTDLEENIAQLAFEKQLMEKYGMELADAVNPSVGSKSEAKGGEEDE
>NZ_CP019721|1063084:1139493|1108980_1109772_-|WP_077708181.1|DBSCAN-SWA
MKKRLSLIQMDVHVNEVEYNYARVQELLSQALSEKPDIIVLPETWNTGFHPSKDLINISDRNGERTKALLSTFAKEHNVNIVGGSVAVAKEDLVFNTSYAYNREGKLVGEYSKMHGFSPAKEDQYFASGTHTTHFELDGIPCSTVICYDIRFPELVRMAALSNTELLFVPAQWPTMRLRHWQVLNEVRAIENQLFLCAVNGCGTVGRVQSTGHSAVYDPWGTNLLEMDTREGISSVDIDLTVVEDIRNKINIFRDRKPELYKL
>NZ_CP019721|1063084:1139493|1065766_1066018_-|WP_077708645.1|DBSCAN-SWA
MYCNLPHTNAVSEECEDVDTHNIYINKNLPHDRMREEIKHELSHIIRDDFYVEHHVNLVERMVRMSQIENGDFNGIDFYHHII
>NZ_CP019721|1063084:1139493|1137657_1138845_-|WP_012863974.1|DBSCAN-SWA
MKKYYPYLITVSHMINDSCQSVLPALLPLFIYTYGLSLEQAGFLILANTALSSLLQPLLGYVSDKINQPRLIALGVLLSACSTGAMGFVTSYESLLVCATLAGVGSSIFHPEGAKIMNRLGGGKKGKAMGTFAIGGSSGFAIGPLFAGSIAYTVGPHGLAAFTIVGLIISTVLFVLMPRIVTQARTIDQAVAMENPTLVAKPLKNYWKYFGILFIIILSQSVNFRVINAFIPIFWTRELGTSPEQGSFALTIFFSIGIFMTYIGGLLGDKYGPIKIIRLSLLIWLPAMFLLTEVPTFSPVIMMPIAYMLLLMIGAAKALSYSPVIVLGQTYLAKSIGFASGITLGVSQTIGGIIAPVVGNLADTYSLPAAMMTLVPFLVVGLGASLILKDPKKLQ
>NZ_CP019721|1063084:1139493|1071245_1071446_+|WP_008715497.1|DBSCAN-SWA
MDRNKLCITVAEAAELASVPQDVIRQWAADFDFPSMKIGARGGKRLIHLDSFNAWLGKRCQARIGE
>NZ_CP019721|1063084:1139493|1125676_1126978_+|WP_021147799.1|DBSCAN-SWA
MRMYDIILKKRANLPLTDEEIRFVIDGYVKGEIPDYQVSALLMTIVFNGMNARELGTLTLAMAQSGNMVDLSNIDGITVDKHSTGGVGDKTTLIIAPLVAASGGKVAKMSGRGLGHTGGTIDKMESIPNLKVSLEQDAFINQVNKIGLAVIGQSEGLAPADKKLYALRDVTGTVDSIPLIASSVMSKKLASGAQAILLDVKVGSGAFMKNIEDARELAKAMVDIGKENGRSVKAILTDMDRPLGHAIGNALEIREVIDTLKGHGPEDLTHECIIMAAHMLVLSHICDYETALSRVQEALDSGAALERLRMMIDAQDGDSRVIDDESLLAIGKFTYDVTAPQDGYITHMNTEQCGIASVMLGAGRTVKDGPIDYSAGILMHKKTGDSVTVGECIATLYASDESLLSNAAKTYLEAITFGETAPIMADTILDIVE
>NZ_CP019721|1063084:1139493|1073131_1073503_+|WP_077708134.1|DBSCAN-SWA
MINVNEVFLSGNVVADAELRYTKTGKPVLTFRMATNKYVNEQQSTQYHNIVCWVDAELYSGLRKGDFVAVNGELRTRSYDKDGSKRYITEIIVKNLTYGLKQNESAASNFDNGFADNDENIPF
>NZ_CP019721|1063084:1139493|1114553_1114880_+|WP_004698343.1|DBSCAN-SWA
MAKFKIQKGLSDADMMKNFKDTENFEDTMLNMERDAKKPVVHQSPKQKEDAFYREFLTEKVETMIGKMLLDIKMEYFKEGEGAFSIQVKREGKNIVLETAPKKVKPEK
>NZ_CP019721|1063084:1139493|1132922_1133825_-|WP_021147805.1|DBSCAN-SWA
MIQELIPLTRPRTLAATLGPTILGAAFSYYAFGAAQGTGLAIFHTMLIFLAVVTAQIVANLWNEYKDFKSGLDAGQKVGNAGSITRGVITPELIITMIKVLMFVPIIIGLYLSATITWYYIPVGFLCILISFLYSGGPKPISRTPFGEISSGIAMGFAIVLITGYAWIRELSLALLIPAIPSTLLVGSIMLTNNIRDIRNDESHGRHTLPIVLGRERALSLMSISYIFNFIWIIAWIIVGHMTWFALLAFLAAPLAFKTIHTLSTNTDEFQLDKAMGTTAGAAMIYQLMWAIGLIMGKLI
>NZ_CP019721|1063084:1139493|1131960_1132779_-|WP_004698373.1|DBSCAN-SWA
MRKFLALAATVILGGALLIAGCGNDNKQAASDGKQVLKIGATAVPHAEILEQVKPILAKDGIELKITEFTDYNTPNLALGDKEIDANFFQHVPYMEEFAKAHKLDLVSAGGVHLEPMGLYSRKIKDLKDLPKGAKIAIPNDPTNGGRALLLLQKQGLITLKDSTNILSTVQDITANPNEYQFVELEAAQVPRSLDDVALAAINTNFALNAGLNPGKDALAIENNDSPYVNIVTVLKGNENDPRIKKLMAALHSPEIIKFIQEKYQGAIVPAF
>NZ_CP019721|1063084:1139493|1128853_1129489_-|WP_021147802.1|DBSCAN-SWA
MNYEIFQLINSLAGTYTWLDTSMIYIVKYLSIVFALLLILLSGLGLYFKDKRLIKTCIHTIAFLGITMIAHSIIGFIVQEPRPFVTHTVNLLIPHVADSSFPSTHAMAMTAISLPILAVYKRLGSILLSGTILTGFAKVFVGHHYPLDVIMGILITYLLFKVYQNYLSSKIDTLLNHPKYNIFRLLINTKLSLYLIKKANQPLSKQFSMKG
>NZ_CP019721|1063084:1139493|1071692_1071980_+|WP_077708132.1|DBSCAN-SWA
MKDKREKALDLLKRYLMFDDEEMQVLREHITSISVSNKSASLDFTILANGCAIFVKRKTGEYVLRITGKGPIKENKVYLALRAREILLDAVMNNE
>NZ_CP019721|1063084:1139493|1112371_1113319_+|WP_077708184.1|DBSCAN-SWA
MKPFTRVLSAFAVGILLQGGVYLYLDQYMFAPTTEFNVAGASKDDTKNFPDVKEGTKYVSYDRQFMAVVTENSLKIYKANESKPTNIDLKGRSISYFNWMPDRNYAVMGLYDSRDVVMARLNADDPEHEVDTKLEDLPRGSKIVDAAYSEATNVVYMKVKVQEHTYRIYRTDANYDTRRVYMQATDIGHIGVFYDEDNFFYDNVRTGDVFMFNGIEGGWRVINPEGRFRFIGVDMDKTIYIARVDEDNNALTVYTGKLGVGFNPVYKYNHPTTFNELTLSDVKNIIKNGSEETTKVTEDNTSSKSSNSSGSKKKS
>NZ_CP019721|1063084:1139493|1121692_1122268_+|WP_008602778.1|DBSCAN-SWA
MNKNSFLDALRNIFKKARVADVESIIEVYEEHFAVGYEKGLTDSEIIKSLGTPEEIYASYVDAGIITDTMNQDGSESKSVNMQEIYARFDDYKERLLPQLPGMAKKASKTLLSIGSALSYIVGALIFIITPAILFLLGSSWQPFENVTAFPVLSIVTLVALGGVGLFGGLTCVFVGTELRGVRERYFRNVD
>NZ_CP019721|1063084:1139493|1105162_1105510_-|WP_077708177.1|DBSCAN-SWA
MKIDYSLCRDILLAVQDFPLPTVNNNDSINFPDINRLTIDYHIYILIQNGLLSGLNASSKSRDYLYLELALTHDGQQFVDLLSSDTIWNKVKDYAIQKAIPLTFDTLIHIAQSLL
>NZ_CP019721|1063084:1139493|1067883_1068114_+|WP_077708126.1|DBSCAN-SWA
MKLEKLKGLLVEHKKTYADLAELLGVSITTINSKMNGKTQFDVVEATMISDWLGLDCSSRVDIFLHNNLHNIQVIS
>NZ_CP019721|1063084:1139493|1136298_1137546_+|WP_077708192.1|DBSCAN-SWA
MDYVSLLQSEMRPAFGCTEPIALAYAAAKAVSVLDEFPNRIHARCSANIIKNVKSVVIPNSGGRKGLTAAATLGAIVGHPERELEVLESATDEDRKWLGTLLDANFCNVSLAEGVDNLYIEITAETDEHTAVVRIENDHTNVTYVSVDGEIVSETVNEIKKAAKTEYAMTFDSIYEFALTGDISGILPQIKQQVEYNTAISKEGLSNDYGSNIGQLLLLDEENPSLETKCKARAAAGSDARMSGCPLPVVICSGSGNQGLTVSVPIITTAEELGKSEDELYRALVFANLLTLYVKSGIGKLSAYCGVVSAGVVSVAGIAFLKGDSKDIIENTLVNGLASLSGIVCDGAKPSCAGKIAISLDGAFMGYKQARLNKNYQKGDGLVAYSVDETIRSIGAVAQGMKETDVVILNEMLKH
>NZ_CP019721|1063084:1139493|1076844_1077342_+|WP_077708143.1|DBSCAN-SWA
MEILSVAFGEKKKIKYEKANSTGVTETYQLITKDEFRPEILDAYVKARIVVIDTFKAFKFIREEWLKIKSINFRWHKELPRVIVAARYVLEITNKKGDKCTISTSWLPIAEETQEKLIPLVEEIEMFVRGTRAQGKLWEEELEDDAVEGETFHINDLVQEGEADD
>NZ_CP019721|1063084:1139493|1069994_1070282_-|WP_077708130.1|DBSCAN-SWA
MKKRYFITYDLNKAGQDYENVIQAIKSASDGAWCTYWKSSYLIRSNYQSAQEVSDKITKYLDSNDRLLVIEVINNTQGWLPKEAWKYINETIFSG
>NZ_CP019721|1063084:1139493|1068129_1068390_+|WP_077708127.1|DBSCAN-SWA
MKSPLQRHMDNLGNKTEEGGETSITKKEPHDEAQKKWIIFRYFNALKYNKDQSLEEKLQDIRYCTRVNLGLFVIAVILTILNITRI
>NZ_CP019721|1063084:1139493|1065215_1065749_-|WP_077708123.1|DBSCAN-SWA
MKKGLVLVTIFVLCVTMMVSAKEFNDARWQWFYSNSDYTGKVDLNTLSYDPATDTAKAWAVWIQTRGFQELREYNIHFADSSVTIIQYYVYRNGSDTVVKEAAVNATRTPAPGSGGEALIASVKGLVGRDAKLTDYKNQQENEAQIQEQKRIEEQQAAEKKAKHERNRDILRGIFGI
>NZ_CP019721|1063084:1139493|1075991_1076336_+|WP_077708141.1|DBSCAN-SWA
MKLDLWVKLNITMVDDSKVSGWTQIYGKHGLAMYNKPFKTLKPIVNDHIDKMNWLAICNRWGETNQIIEVNTSKIKKYVIKECVQPYDTEEEYYAIKEWYRNNMRRRTLLENNG
>NZ_CP019721|1063084:1139493|1090079_1092416_+|WP_077708158.1|DBSCAN-SWA
MANKVLEMAIAIKGKLDGGLSSSVSKASQELNKLSNVIKDQQAQYRKLQAISQKTGNVSDRNAAIAAEQKLNSMLQRQARLRSNIASQTAHQNAISKMGGASPLAGAASAAQGASAAVSGITGKLASLAMVAAGGFGIGAIIDNVVNAGEALYQLSNKLHMTTAETAQFKKIMTLSGVDVEAAAKSFAKMDKTLAGGGKSAEALQGYLSQFGVSLTDANGKLLPMNQQLDAMAKGYQNAVAQGRGQEFMLETLGAKGMELTKVFENYADAQAAASQIKGVGIDPKSLHEIWLQMNILKAEATQVALGLAQAFIPIAQQILPALIPVLQAVVTFMKDNKEAIAAVVTNGLKLALLYGTATKLASGITTITTAFKGVETATGAFKAAGALIGGPWVIAIMAIIAVIYLLVTNWDTICATLTSVWDSVCSGLSSIWDSVCSALSSAWSAIISGIMAVINGFLSLGLSAFNALKAAIIAYVNLWLNLPTYIGMAVGFIIGIILRLPEIAVQVGTAVISAVVSFATECYNFAVTTFSAMVDDIYNFLINLPMYMITLGAEFVAEVISFASEAYATATSWISSLVNDVINFIMNLPSACADAGAGFVAAAGQWASDAYNAVLDWIKQIPSAVSNAISGAWDSIKAQFSGGFTVGVQAAGGNAYANGGVITSPEVALIGEAGYPEVIVPIDGSANAMNLWQTAGRMLGVSGAQSAVAPTVSLAPSVPVASSSSSSGAPVQITFAPVINAGNGSTDDIMSALDAKMREFEQMMRSYTAGQRRLSYD
>NZ_CP019721|1063084:1139493|1093765_1094230_+|WP_077708160.1|plate|DBSCAN-SWA
MATDILSTLVDMIFIGNVSSTIPEEGKAVVTRLDREGVVTAPLSVINRGAAHDKDYWMPAIDDQVLCIMLPNRSGRGFSDGFIIGTFFSSADPTPGGADNGKRVLTVPGDMTLNVGGTLSINSSGGDVVVNGISLVHHVHGGVVSGGSTTSGPE
>NZ_CP019721|1063084:1139493|1101650_1101968_+|WP_077708171.1|DBSCAN-SWA
MLKILNCNPHFMRDPVPVSNYAEAWDVICSMQRELGQGILAVDREAWEVLGLAEHFPEFVWKENVKAVYINSDKSLLIPAPRRYCRSNVLKLIKFFGLHYSIREI
>NZ_CP019721|1063084:1139493|1072301_1073099_+|WP_077708133.1|DBSCAN-SWA
MRKRKKVISKNMIEVLDYHTSRTYRKNGKRVKKKNITPEAQKKQNEKQAEAMLRMLIDNNFTTNDCYITLTYKEQPATWEDAKKDIQNFIRRLKRKYKKLGKELKYIYIAEGKTRIHFHMIINNAELYSDELNELWPHGMHKLMLYQGRAEDAVKLASYFVKEKRSACYSDKEDAFKRRWNSSKNLEKPKVKTEILKPSEWRDYIQPPKGYYVETDSVVESVSEEGYPYRFYRLIRIEEVKHGTTRNRHCSRGNTRSINNSIMRN
>NZ_CP019721|1063084:1139493|1068376_1068949_-|WP_077708128.1|DBSCAN-SWA
MKALPISNLQLSQNSIEQEYLNYKEELDSFDSHAHSLTNENLEKLILFINRKSKTYAELKAEVSILNDATLQLYLSNTPKKKVEPPFYSIERISAISNTTSLIHSYFKLVTIPKDFFAPYYFDDSDEFQLTVSGLNFLHQLEKENHTLQLAEESLRISKESAKYGKFAAWLAGIGIFTTIIIAILTFIFS
>NZ_CP019721|1063084:1139493|1134067_1135012_+|WP_021147806.1|DBSCAN-SWA
MRTLNKKLMTLACATCLTVGMGAVACADTVDLGYGMYGTTSPTVKAVEVMHISTDTRLRNQEQDKFLKVANKSAVDTINNVVKAQTGVAVEPVKGDFLDGYSFYQLQGTDKQGHHIGGLIVINYSKNAIDQVIGMNKTILEKGADAEKAALKHSISKYVESYSKETAQQQLQGLKSNTIEGAKLAKDLKTINDKLPSQIIGVFDKMLATDKKSSPKSIEEIRSYVDFMAKQVSLDATHVAYKPVQTRYGTAVTGDLRGSLKYDGFRNTYSLIGYAVPTDKGVSLQILMSDDSSYDYWANELNHMYQTQSLKGGK
>NZ_CP019721|1063084:1139493|1066067_1067264_-|WP_187658831.1|DBSCAN-SWA
MTKSSCNGILCTWYLGRLCKKLQPEKGHVHLCVHGLFIIMKSFKTYDEQIDILSNSGLLPKYTNKSPSPDIKGPAVIHIHNPFKHPTSDRDIRMTILKNSKSYVKDLLQTYGYYNIINQYNKPFLTNDEYIDDIDFFKLFSIQQVDARIKNLIFYPILQIEQRLKTCISYEFAKAYGPFDGDSIDCHYIEPYLNESNYTQNLKTKKNELKHELLIKRLKKIYKDTTFKPFTHYRTKHGHIPIWIFINNLSFGEMLHFYEVLKIQDNISSFFHMTPSQLRTSILFLNQVRNDCAHFSSFINHDYPKLKESLPLLVDFTTTFQFEYQDNITNIFKLLIVFKYLLPNNAFINFTQAIDKDVFSMIYKEYIPVISEFMQDVLMAPSSKAYKEKLDFLRAQQI
>NZ_CP019721|1063084:1139493|1101097_1101481_+|WP_077708648.1|DBSCAN-SWA
MSSWNELKGRLMKAESSINNSEKALQQANSLTATQGTALTELKIINEERTKELNALKAINEKQGQELTKASNLLTTQEAKLNEASTSLEELTEQIKRNKRTEQRLKRQRDTWAVVSGVFGLAGAIRR
>NZ_CP019721|1063084:1139493|1098879_1099269_+|WP_077708167.1|DBSCAN-SWA
MNQYVFILNDKGERITSLCDNTLSRDDIMAQAEHDYPNAQYVYSADGDSMLDEFMSGKLYVNGKFIEPDPYVPTKEDKINAIKAEYEPRFKTLEEAQRRLLLMGKPTNAISTQYIKLNNEMVARIKEVQ
>NZ_CP019721|1063084:1139493|1111424_1112363_+|WP_004693677.1|DBSCAN-SWA
MFKKNWVKFIIMVFLFTVVTSPFVVLFGPFNNVKRAVIGAILQSRHPHYITWLFNEDELQSILGTVGVVKSQDLFKFNAREDKTLNLEKIQSARYVGYILEIPDPRRIQVGTAANIQEKGDTTSNIAKMNNAVAAINGGGFHDPNGTGTGRLPYGFILHDGEYVIGKDVGPDEDVDFVGFSKSGNLIAGNYDKTQLSDMKAMEGITFGPPLIVDGKKMITEGDGGWGVGPRTAIGQKKDGTVLFLVIDGRQPGYSIGATLRDVQDILFEKGCYIAANLDGGSSSTLYLNGKVVNKPADLLGERMIPTAFIVK
>NZ_CP019721|1063084:1139493|1084358_1084697_+|WP_077708150.1|DBSCAN-SWA
MAYFEQVNGVAADYLLGGGGVPVLTQNVKVAAGDYKRGQVLENNSGTFQKIASGKPAGIVVSDTTATTEHNVLTVYISGRFNREVLVVDQAYKINDHEADFKDAHLFLTSIK
>NZ_CP019721|1063084:1139493|1089613_1089910_+|WP_077708157.1|DBSCAN-SWA
MSKHNTMNETHEQTGIELVKAGHSLQFEGISGYTLIKCEKSAKGEDKTITVPALSMTYQAHVAAAVCGCKVDDIYSLPAADFTRVCLEVQNFLLNSEK
>NZ_CP019721|1063084:1139493|1089057_1089591_+|WP_038125816.1|tail|DBSCAN-SWA
MASINQVPEVLNDFRVYEEGSDNCLGVAKVELPSESVMTQTVKGVGIAGEVEAPVIGHYSSMETKLTWNTPTETTHRLTGGRGVRLEVRGAIQCWDSGKDKYVIVPTRAVIRGRAKSKENGTYESGNTIDATNTIETTYLKLEQDGKVVREIDKYAYKDSISDGTDFLGDVRAALGI
>NZ_CP019721|1063084:1139493|1077337_1077685_+|WP_077708646.1|DBSCAN-SWA
MKDQLIYVAHPFGGNKENKFSIDTIMKNLVMLDKNNTYLSPLHNFSMVYFEDEYAKGLKICLDMLNRCDALVLCGDWETSKGCIGEWSFAIAKGMPVYTWEEWTDKLKEQGNQYR
>NZ_CP019721|1063084:1139493|1127391_1128849_-|WP_077708190.1|DBSCAN-SWA
MKYVLKNKNYHILIVLIFSAIIYFIGNAYLSITDPAESNYALTAKEMLLTKNYLSPQIFGHYWYDKPIFYYWELIVGFKLFGITNFGARFFSSLLALCNIFLIYRFVKAQTNHVIALVSAIIVSVSAEYWIIAKSLITDMTLGLYFNATLMSFYIGYIHHKTGQRGYKRYYLLAYIASAFAVLTKGPIGFLLPGLIILVYLAIRRDIRELFSLQIIPGLLLFLSLGGSWYYYMYITHGNDFINVFLGVHNWLRATVSEHPRFNVWYYYIPITIIALLPWSIILPKSIYSNRKNWFTNIPFHSFLAVWAGIVILFFTCMATKYSTYSFPALTPLTILIAVMCYKRINLIYKTAFVMGIAYIVLTFAVAVPQMKKASTPSISQFISQSISDDSILVQGSGRYRVSPTYYSGHEVYQLLGPNEVAPDPTTISWNAKDVMPFISINDLPTNKKIYLLVYGDDYLPDTINSDNLSLEYSNAEGTIYQLHR
>NZ_CP019721|1063084:1139493|1081421_1081667_+|WP_060923706.1|DBSCAN-SWA
MATSYSRKPRLIDVRLEWYVKAEEAILTGQSYTIGNRTLTRANLAEVRKMIDDLVARGAKLPGMDTDNGRGNRSKRVVFRD
>NZ_CP019721|1063084:1139493|1122824_1123412_-|WP_077708189.1|DBSCAN-SWA
MMTEQEVKQLLIDTQAILEGHFLLTSGLHSPMYVEKFNVLQHPKYTEKLCKELAERFRDQNVELVIGPMTGGILLAHEVGKALGTRAIFTEREKGVMTLRRGFKIEPGTRVLIVEDIVTTGGSVQEVVNVVNQSGGEIVGVGLLVNRSGGKAEFGVPHEKVQALLNLKVPTYKPEECPLCKDGIAMTERGSKHIK
>NZ_CP019721|1063084:1139493|1074818_1075235_+|WP_077708138.1|DBSCAN-SWA
MKPLIYKGLRKNLNRSEWVISDEIKQSYSQIRLLAIENDTYAWVQIEDGTLCRGSEAKDTLGKRIYEKDHIEFDCKSIQEKPMVGEVYYSVDKYQWRCKAINQQNKQNDAVLDFDLAFVVNNGNARVVGNRLEGYEHE
>NZ_CP019721|1063084:1139493|1094239_1094716_+|WP_077708161.1|tail|DBSCAN-SWA
MYIGYLADIVFYTALDNVLTVSDVTRSGSARWEKHNLMLEKPVKQFSGPDVEQITCKILISASLGQSPDSTVKKLRNYRDMGAVLPFIIGGKPVSQNYFVIMSMSEDSLFTDAYGKTQSIEVSLTLEEYSDNNTVEEKSMLNQYGQKFNKVNTILRRF
>NZ_CP019721|1063084:1139493|1073796_1074024_+|WP_077708136.1|DBSCAN-SWA
MYGAMEKKKALRVLGLKEQYKTNDLIKYAEVKALVNKGISYREIAEELGVGLSTFKNKCKELGITSKRGRKSNKH
>NZ_CP019721|1063084:1139493|1079508_1081413_+|WP_077708147.1|terminase|DBSCAN-SWA
MKTAKELWQYASKMGLKPLPKTSVSQWADDYRMLSQGISAEPGRWKTSRAPYQKDIMDAFTQPGINRVVVKSASQVGKSDIMNNVLGRYAHLDPCAVMMIQPTIELAQDYSKSRISPMIRDTKVLSQVFYETKSEDGAKTRDGKNTILSKLFPGGRLIMCGANSPAGLASRPVRVLLADEVDRFPDSAGTEGDPVDLAAKRMTTFWNRVMGLFSTPTNEGSSRIDVEYQTGTQEEWQHECPNCGEYHLIRHTEMECETKEHKDAKGRKIIVVSDVKWRCPDCGSTFSEDEMRKVPQKYISKNPAALHNGIRSFFVNGFTSPWLTWNDIMREWLEAKGDPTREKVVMNTRFGESYAQQGAFEDYQQFIRRREKYGADLPDGVLLLTGAVDTQDNRLEYEITGWGYGEECWGICKGVILGEPDNKATWDALDAVLDKVYRFKNGTGLKVARAFIDSGGHYTSKVYEYCEKNFSKQRFAIKGTAGTPGIPLNYKIGKASGSKIPLVMLGVDDGKQQVMSRLAIDEPGAKYFHFPLDEEFLGTRGYDELYFKGIISEHKKKVKRKGVIHEIWEPTAGVRNEPLDLRVYNLACMNSIHPDWDRLAEVVKGGGYSATTVTAPRKKPMRNRVRRASKAADI
>NZ_CP019721|1063084:1139493|1102319_1103168_-|WP_077708172.1|DBSCAN-SWA
MFFFFPEESPSNADNTYQSPFESIKQIDDDGNEYWYARDLQEILEYSEWRNFSKIIEKAKSACETSGHAVQSEFVDVNKLVDVGANLQRSIQDIVLSRYACYLIAMNGNPRKEVIALAQTYFAVKTHEQEQLELQKEDSLRLQIRQDIKEHNISLAEAANQAGIKEPKDYAIFQNEGYKGLYGGLGVKQIHAKKGLKKSQKILDHMGSTELAANLFRSTQTDEKLRREGIKGKENANKIHHDVGAKVRQTIKELGGTMPEDLETPTKSIQQIRKESKKALSK
>NZ_CP019721|1063084:1139493|1099427_1099979_+|WP_077708168.1|DBSCAN-SWA
MDILNDILIMLISGISHEHIVSMGVVIILTTTLLFVDTIQRIAAEVLRYNKDNHRPNNPITLLTTLTWYGWGKGRYIDETTGERRRYLMSERLRGDLLKKLCIQYPAWMILSIVFISLPDIPIPNTNLFLDHIFSYAFMLIPFFAECWSIIENLREMVEDDLIDIGKIFQYTIEIIKAWRGNG
>NZ_CP019721|1063084:1139493|1107075_1108449_-|WP_077708179.1|DBSCAN-SWA
MFSFLQPKEAKSSVPQSMIMNLYYKYRLQSLIGIFIGYAAYYIVRNNFALSTHFLSDILHMSKTEIGLLSSGMLIAYGLSKGFMSSLADKASPAKFMAFGLICCAIINIFMSFADSLAFFLVLVVLNGFFQGFGVGPSFITLAKWYPKQERGRYGAIWNISHNLGGGIVAPIVAAALYFTTTDHWQLGSYGVPALIAIIIAIAISFLIKESPEREGLPPTSEIIADTAHKAHRSSEAPHMSTREIFVKYVLKNKNAWYVSLVDTFVYMIRFGMLTWLPIYLLQVKGFSKAEMSVAFLFFEWAAIPSTIFAGYISDKFFKGYRMPPAIIAISIIFFCIFGYWQSESLLWVTFFAAIVGCLIYIPQFLASVQTMDIVPPFAVGSAVGLRGFMSYIVGANLGTTLFGVLADKFGWNAGFYLLLVACVLCITFCVLAHFGAKELDAKEAELEQLQPAEANS
>NZ_CP019721|1063084:1139493|1096144_1096804_+|WP_077708164.1|tail|DBSCAN-SWA
MILDSKYTSAEHLPSSIDREPVKSLAKTWDDMLAEFMNTNTLLLWSSIDTEPESVIDHLAYQLHVDDYDSGLPIETKREMVKNSIDIHRHKGTPYAVEKAVQTIYSDSKTEEWFEYGGKPYYFKVTLITAPLRGETDIAKLVRAINAAKNVRSWLDGIEFIRRINFNKYFAGWCGVSRKVNIKCDFTNAWRINLNTHVTSYTVESKKTKINVVLDNSVR
>NZ_CP019721|1063084:1139493|1086010_1086364_+|WP_077708647.1|DBSCAN-SWA
MRFRDYLESDIDDVFLNEDEFAEGHNLNGTVAKAIIQSPTARESFLSNGSHVSNDGLHGVSVFVHCKLKDIPEIPSQGNVFRLDDDVYIVQSATEEDGLVSIELRAEARGGVDGWLS
>NZ_CP019721|1063084:1139493|1063084_1064158_-|WP_077708121.1|integrase|DBSCAN-SWA
MAKKRTDGRYQVSKMINGKRKYFYGSTKKAATEAMEKYVNANQSCANFDATISLNTWINIWLQLKAKTITPATYQSYTGIINRYIRDKIGGVKLAEIKPNTLRYVFESMDGLSSRTISYTMTILGSILEQAVKDDIIPKNYMKNIDRPKQVKVRHMVTLSADEVKSFLSNISNSEHHTLFKLAFATGMRRSELLGLRWSDIDFKKSTISISQTALKIGSTAVISNTTKTTSSKRIIAIDTDTLQELIKHKTVIDKRRIKTMNWINNNLVFPGIKGAPRCPDEVSKLCKKYANLIGKPTFTMHGTRHTHATLLIENGANMKAIQERLGHASFQETMDTYSHVTPKMEDDIVERISKIF
>NZ_CP019721|1063084:1139493|1078944_1079475_+|WP_077708146.1|DBSCAN-SWA
MKITDDLKTATASQSNLAKALGLSRQRVSQLLQEGVLATDEKNQILVIKSVINYVKYKGQSSAEEESSSDDAIFEVEKAKNERAKRKIAELKLAKMNGEVYSADTVEQVMTEMLVNLRTQLLGLPTKLAPQLQNVTKEEAYNLLTQEIEDKLSELSEYTPSLFMDSDELDDDKAPN
>NZ_CP019721|1063084:1139493|1092615_1093776_+|WP_077708159.1|DBSCAN-SWA
MSLQKSLAKVQKWKKDLTPQTKLARRAWCTIGYQHWGSKESKDITDDISKYLLDVTFTDNLSGTVDDVAISLEDRGRLWVGDWYPVKGSLLEVAINTVAWEKLGDEQFTLPIGKFEIDEFEGSSLPDVVKIKGVAIIGSTDLREKKKDKSWKTTTLKAIATEKAKDNKLKLVWDADFDPPLKDASQSAESDLAFLQKLCNDAGFSLKVSTEQLIIFDDYKYENVKPKVIIRRPGGQYQPVQTKEGEQPPLIITRALSYSYKSKTREVYRACHVKYTDKDKKSVIEDTFEDPDRKGHTYLAVLEVNEQVKDKAEAKRLAKKKLREANKEADTMSFSFPGNPLIMASVTVNLEGFGVFDGNYLITKATHTLGANYSTSIDVRRCLNGY
>NZ_CP019721|1063084:1139493|1098001_1098853_-|WP_077708166.1|integrase|DBSCAN-SWA
MRRYAVILKRRQRNTITLRQLFNEWLPIHSQAITKSVVKSYHIAFKHISNIADMPITDIHFQHLQNVINSMHVKGLSYSSCKKVRTLLNQLFNYAIIQDYPITNYASHLNLGPNIPMIKRRVFTRQQINKLWAIDNSYSQMILMLLYTGLRIGELLNLRRQDIHRRSSYLIVRHAKTKAGEGRIIPIHHRIMPLIEQVYTSTEAYLFTISYTTFHKNFKDIMKQLNCKHTIHDTRHTFASLLDSVAPPNTLRSLLGHKQGDITTRVYTHKTIRELRKAIELLK
>NZ_CP019721|1063084:1139493|1086884_1087364_+|WP_077708154.1|DBSCAN-SWA
MTPLDVSDGIAAYLMDELRKLNETSDVTTSPIRVWSGFLPRVDKNEDKRKLCPAVVVHPYSVSDADSSTVGITVLVTTYDEALTKGHVGLYHLLEVVRERLLSDNPVALKYEIKENTVNTTIPDDQPYPQWVGYLEFEVYIPVIRRNLNKIFTDNKVIE
>NZ_CP019721|1063084:1139493|1076328_1076787_+|WP_077708142.1|DBSCAN-SWA
MDNKNILDACCGSRMFWFNKKNKNTVYMDNRTEETMLCDGRKLIVKPDIMADFREMPYKEETFHLVIFDPPHLLRAGDESYLKLKYGRLGEAWKEDIKKGLAECWRVLKTNGTMIFKWNEEQITLPQVKKLLPCEPIIGQRRGKTIWLVFFK
>NZ_CP019721|1063084:1139493|1131137_1131857_+|WP_021147804.1|DBSCAN-SWA
MGKVLIIEDDMGIYELERDYLEIEGYEVDIQTNGVDGLKAALDYEYDLIILDIMIPKKDGFSVCRDIRKEKEIPIIMVSAKREDIDKIRGLGLGADDYMIKPFSPAELVARVKSHIQRYNRIRNSLSPTVVLDAKITAGSLEILLDSHQVFLGGTEVNLTPREYDILVLLASSPNRVFTKEEVFESIWGIDSLGETSTIMVHINRLRAKIDKQFQNEEYIDTVWGVGYRFHKWDNYIKQ
>NZ_CP019721|1063084:1139493|1123408_1124128_-|WP_004698328.1|DBSCAN-SWA
MADDRLIVALDVSTMDAVKEIVLSLGDSVSFYKVGMELFYAEGAKTIRFLQEQNKQVFLDLKLHDIPNTVAHGVASLTRLGASLITLHGQGGPVMMKAAVEAARESGKELGVERPKLLAITALTSFDDESWTAIGGQLPISDQVIRLAKLAKDCGMDGVVCSALEAKMIREACGDDFLIVTPGIRPSFATTDDQKRVATPASALQDGASRLVIGRPITQAENPREAVRLIIEEMEKVSK
>NZ_CP019721|1063084:1139493|1124316_1124946_+|WP_008602770.1|DBSCAN-SWA
MLDFVALDFETANKFKNSACSLAVITVKDGQITKKAYSLIKPPFMSFDDECIEIHGIQPKDVLHEKTFDQLWNAIYENHLKGNIMVAHNAKFDMNVLRATLDYYKIPWPELDYACTVKLSRAVWPDLVNHKLNTMAAYIGVEFKHHYALDDAETCAKVVLEAAKLKGVNSLPDLLKATGVPLEPFIDDKNRSAQDALHKEPEPEQMSFF
>NZ_CP019721|1063084:1139493|1069855_1070011_+|WP_187658832.1|DBSCAN-SWA
MKIIIEGTAEEIWALMEKEPCCEQSSSNQWFPEDSNRKYYEKSTSGPNLKK
>NZ_CP019721|1063084:1139493|1104976_1105192_+|WP_077708176.1|DBSCAN-SWA
MIKQEREIKDSKHFQVNRLAFYVQLKTMTVDNLKKYPHWNSERMDVIYYLAKYGEKEELKKLSKQTLCNVD
>NZ_CP019721|1063084:1139493|1069349_1069694_-|WP_077708129.1|DBSCAN-SWA
MDLYLLDKKSFSYLEQFYQRNLSPQQLSGITGLSAYNMALELSYLLQLNFITNTDGFHSDSEGILSNNTYEITPSGRSYYEAVLEQRKIDKHATCRSNLALFLSFIAVIISIFK
>NZ_CP019721|1063084:1139493|1117226_1118567_+|WP_077708186.1|DBSCAN-SWA
MNLQIRIWISNVVLFVVPILIAIILFLLYFTGLRILANAGYYLRIEQEQQFKSVSRITETITFYGLENDLINSLVKPSYSLLDPKEVYVEVLDQGSMVYNYGNPQIYSASAIVGLIDVNPELQGIVYQSNNTFVYEMRKYDGRHSYVYHIAIRRATHGSDSLMESVSFYIIVVSILLFIVTFFAINRFVTRFIMIHVKNMTKSLEMANRQIEMEQEQQKELLAGISHDIRTPLTAIKAYAEGVRDGIAPTEEQQKRYMGIILKRANDLDSMLEELFLITTLNYKKESRPSERIELGQFVRDFVEDHLAPYQSKGLEIKARIATETPFINANPQLLQRVLQNVLNNSAKYKMTDIGHCVIDVTSDDDFVYCVISDDGPGVPPESLERLMRPFYRVDSSRTNPQEGSGLGLSIIRRIMEIFEGRVMIENVRPHGLRIILEFPKQGEES
>NZ_CP019721|1063084:1139493|1108661_1108874_+|WP_077708180.1|DBSCAN-SWA
MKYLRRELNQVEKEYVKQFGEDSLNRVILHDPNTKDKQEVQDTIDILKGAIAKNKPLEQVPEEMWKLIEF
>NZ_CP019721|1063084:1139493|1099270_1099411_+|WP_174892239.1|DBSCAN-SWA
MPKYIGDSKVPVMEFCEYCWEVLNDDGTCPTEGCVHNDLMALDEES
>NZ_CP019721|1063084:1139493|1070471_1071137_-|WP_077708131.1|DBSCAN-SWA
MDFIPIIISLAALLLSLLSYLRERRLITVDFDANCFALDVTKNIEAHDNVFENSTNQYAIFTTAIIVNASTTNSSYFDLRAYNPKTNENHFLCTLSSVPWLRDNPSLLISPFGPKALENFIIDLPKSRCGPITSGSCLELPILVILNKNISIKEGICIEFKIPQYAWLPWHRSPLSTSNRKKFKLYKVHYNLSNFHKILSTQNAMDTPNETEETTTAINGK
>NZ_CP019721|1063084:1139493|1121376_1121706_+|WP_077708187.1|DBSCAN-SWA
MQVQLKKGVMDMLVLALLTQNDRYGYEIVSTISEYIEISEGTIYPLFNRLKKEKYVETYLKESSTGPSRKYYHITNEGRAAYNKMRQEWDDFSVVINMLLKGVDNNEQK
>NZ_CP019721|1063084:1139493|1095026_1096148_+|WP_077708163.1|plate|DBSCAN-SWA
MRLSDLPNVEFFNTDKEHVQQKVFDIYTTITGRTLGEGDPVTLFLNVISEIIIRLLNDANYAAKQNLLAYAEGDNLDHVGAVPAAVERLKATKATTTIQATLSAVRTNSVIIPKWTRISTGSGEYFATVEDLVILPGQLNGSVKAEAQIAGARGNGFKPGEISTIIDPIAYVDTMRNITLSEGGSDTEDDESYRERIHEAPESFSVAGPEGAYEYFTKSASHLVADVGVSSPRPGEVNIYPLLAGGGLPGQELLTTITDYLSDKKRRPLTDKLTVLAPTTTQYNIDAKYYIEKGADATVVKAKADKAVNDYVIWQKSKLGRDIVPSRLVQMLMDVSGIKRVEVTAPIFTPIAEQSGVAVANTIAVALAGSEEE
>NZ_CP019721|1063084:1139493|1119919_1121017_+|WP_004698370.1|DBSCAN-SWA
MTFSKYKKTVIACILALGIGVGGGYYFFGSPVNTQPTNVREQTKQTKPITETRNTYVVQAAKESGPAVVGITTQVFQKDIFNRTIYAGEGVGSGVLIDNDGHIITNKHVVAGARNGEVTVSLSDGSTVTGTVIGSDSQTDLAVVKIKPPKDIKPIKIGDSDSLQVGEPAIAIGNPLGLEFKGSVTSGVISALARTIDDQGQRFPLIQTDAAINPGNSGGALINADGELIGINSSKISKEGIEGMGFAIPINSAMTIVDSIIKNGKVIRPYIGVWAVDRQTAARNNVTYEGDGLLVVQLDPNGPAAQAGLVEGDTIAQIDGKDITTLLELKEQIDAKSPGDTILVSYTHNGKMKSTQLKLGEASSN
>NZ_CP019721|1063084:1139493|1126988_1127414_+|WP_174892240.1|DBSCAN-SWA
MIEKETHMTEQEIQNLIDRAIVAREKTYSPYSHFGVGAAILCEDGTIYEGCNIENASYGLTNCAERTAIFKAVSEGHTNFKALAVVADTEGPCAPCGACRQVMGEFNIPIIIMRNMKGNIKVVSIEALLPFSFSSNDVIDR
>NZ_CP019721|1063084:1139493|1092408_1092612_+|WP_060924349.1|tail|DBSCAN-SWA
MTSYTTIQGDMWDLIAYKVYGNERYINLLLEANQKHRNTAIFSAGVVLTCPDVPADSLPEFLPPWRR
>NZ_CP019721|1063084:1139493|1087601_1089041_+|WP_077708156.1|tail|DBSCAN-SWA
MAFYHGVKTSEQATSVIAPVQTTAGLPIVFGTAPVHLTEDPSAVINKPIICYSWEEAVQQLGYSEDWTHFTLCEAMYAQFKLYGVAPIVFVNVLDPAKHKKSTTTTATLTEKKCIVKAAVLLNTLQVSSGGQTGVANTDYTAAFDDKNQLIISVIKGGKFDSASTLDLTYDELDVENFDYKNVIGGVDSNEKATGFELIDTIYHHFGIVPGLIAAPGFSQHPTVASVMKAKSRVINNLFGATTLVDIDTTQVVKYTDAYEWKKGNSYTGESEVVCWPMVRNGDYMFHMSTHIMGIIGKCDASNSDIPTLSPSNKSMNITGLCLANGKEVMLTHSQANLLNSQGIMTAVNINGWVSWGNYTGAYPGTTDVKDTFICVRRFNDWDDQTFILTYWQKVDMPILPRNIKTILDSETIRLNGLTSRGFILGGRIEFKEAENPTTDLLNGIIRFHKYRTPPIPAQEIESISEYDVSYFKTLFQTV
>NZ_CP019721|1063084:1139493|1129648_1131133_+|WP_021147803.1|DBSCAN-SWA
MLFNWFNSLGVRRKMIISNLLIIIIPFIVLLTALSIVWGVIRYTNPVNHRQWMMLAPSTIQSQVFQLGLEQINKKLSKESTSISDILDSSAVLEAQGLDIVILKDNKIVYATPDIEPNIMLSNVKNMINGLESNHYLNWEGNQFTYVNSYDMGLTVYGAGRIPFMTKSMGPESTDKKMVEGAFGIGILMIIAIIIGIGLYISNRLGEYILRPVIDLKQAADDLKNGIVPKRIAVRNHDELGVTCEAFNNMQESLLKARQEQDLYEERRREMIAGVCHDISTPLTSVKGYASGIIEGIANTEEKQARYVQRIYDMAGRIEHLVNMLSDFSQLELKQIHYNRDTYALDDLIREYIRERHLNNHELIVLHESYSAEDSLIVIDRIQFYRVLDNLVSNSIKYRRGESVSIDISTAKIDNGCKLTFSDDGKGVPTEMLNRLFDIFFRTDEARTEVANGNGIGLAIVKQIVEDMNGSIHAEHNDSGPGLSIVMEFPLDKE
>NZ_CP019721|1063084:1139493|1104151_1104628_-|WP_077708174.1|DBSCAN-SWA
MGTYRTAQVCKNGHVITSNIHNSAHLSNFCPECRAETITSCPNCNTPIRGEYDVPGVISFSTYTPPKYCHHCGYPFPWTEEKINSISKLLDMQDQLTEEEKKHFMSYLPVIFSETPQSEVSALQLKLLFNKLPSEISSLAKRLISDAISEGIRNILFP
>NZ_CP019721|1063084:1139493|1094718_1095030_+|WP_077708162.1|DBSCAN-SWA
MSATYEIKPVTDNRISLAPESEVAEILQNVQTIISTVRGSVPLDREFGIDGRIIDMPIHQAQAHLSNDIFQQIKRYEPRAKISDISFTATQNGALIPKVMVTV
>NZ_CP019721|1063084:1139493|1122277_1122640_+|WP_077708188.1|DBSCAN-SWA
MRRIIITAILTVICAVGACTSFAVNDLPNFGEWMKTNEQQFRKPHRHDGPNQYMDKHMMDGNNHMMPQDGMGPNNGQHMHSNGQMPPQGQMPMQGQPPQQPNGNAPQQQTDQGAPQTTQN
>NZ_CP019721|1063084:1139493|1135925_1136297_+|WP_021147808.1|DBSCAN-SWA
MKTISTDKAPAAVGPYSQAKVIGGLLFASGQIPLNPATGTVVEGGIVEQTEQVCKNIEAVLTEAGTDFSKVVKTTCFLADIGDFKAFNEVYAKYFTSKPARSCVAVKDLPLGVIVEVEIIAEV
>NZ_CP019721|1063084:1139493|1124960_1125623_+|WP_004698377.1|DBSCAN-SWA
MLGKELLAYVDHTLLRPTATWDDIKEVCEDGIRYKTASVCIPPDFVASAHEAYPELNICTVIGFPLGYETTEVKVAETKQAIEEGASEIDMVINLGDVKQGDFEAVTSEIEALKKACGDKILKVIIETCYLTDSEKVALCKCITNGGADYIKTSTGFGSGGASLEDIRLFKKHIGPNVQIKAAGGIRSITDMKAYIAEGCSRIGASAAVELLKNHLNEEV
>NZ_CP019721|1063084:1139493|1078260_1078554_+|WP_187658834.1|DBSCAN-SWA
MKHKRITSKKTIQEIRKQYCEICGQRTNIEPHHINTRGSGGGDIKENLIQLCTQCHINTHSGQYPTKDDCLNKVAEREGITYYEAYAINRRAMGYDV
>NZ_CP019721|1063084:1139493|1085774_1086011_+|WP_077708152.1|DBSCAN-SWA
MKIRVLKGYLAHEGEMYGKGEVVDIKKETVALSLLESDKFESAEDDPIEVTEPLEVVPDEPEEEMELPEVDAEVTVKK
>NZ_CP019721|1063084:1139493|1106324_1106966_+|WP_077708178.1|DBSCAN-SWA
MIFNYGETLRIRRDLYTILGKIRYIDTHGKIGYEYKLVRHKNNAEFWLSWDKKRDAYQFSKLCGKALPADMKLIDSGYEMVTGTWGEVDVGTTDTAKYKEYENADGTATFSVQEWAFETEYSKGFYINKEYVSVEKDSEVTESILDKMDTIKKLKFIGPIGWILGNLLLYMPIFDIKILNDVRDVLTWPYIVAGSIVLGIIVACAFIISRTMR
>NZ_CP019721|1063084:1139493|1077681_1078107_+|WP_077708144.1|DBSCAN-SWA
MTGREYLNQIRDTDLNIKCKEREVFRLRQDILCLQAIDYSKDIVSGGKPITIADKIANLDAVTEEIMKEWSDFLQERERARFMINQICSTKQRIVLVDRYINGCTWEKVAELIDCSRQNVHNLHKRAIKNFEEIYKKVAII
>NZ_CP019721|1063084:1139493|1067302_1067704_-|WP_077708125.1|DBSCAN-SWA
MSTDERNAINKEIGERIKAIRKQKGITLADLGARLGISESNMQRYESGKIASVSIDFINRLAPILEVNPEWLIGWDKDDTPQGYYLDSETAEYAEYLRTRPSARLLFSASRGISKEDMQKAVEYIEFLKSKYK
>NZ_CP019721|1063084:1139493|1115424_1116777_+|WP_008602782.1|DBSCAN-SWA
MAKKLRICETVLRDGHQSILATRMRYEQMEPVLGLLDDIGYEALECWGGATYDSCLRFLNEDPWERLRKLKANLKNTPLQMLLRGQNLLGYKHYSDDVVEAFCNAAVKNGIDRIRIFDALNDPRNMEAAIKYSKKAGAHVQSAMVYTISPVHTTESFLKVAETLVEMGTDSLCIKDMSGLLGPADAYDLVSTFKKRFGELPIDLHSHFTCGLASTTYWEAAKAGVDIIDTAISPFAHATSQPATETMIEMFKGTEWDLGLDLDKYIPLVDHFRKVKQQIAEEFNLKPASDVIPAVRRYQIPGGMLSNTQNQLNEMGMGDRFFDVMDEMPRVREDLGYPPLVTPTSQIVGTMAMMNVMMGDRYKMVPNEVKDLVRGKYGQLPGTISDEIRQTIIGDEQPITCRPADLIEPELEGYRQDLASKGYNGITDEDVLTYAMFPEVAINFFDANRR
>NZ_CP019721|1063084:1139493|1086351_1086885_+|WP_077708153.1|DBSCAN-SWA
MVELELDKSAVKTIEKALETLKEDRVRRVCQAASKRAATTARKAGTQALRNIYAIKGVSVVKSGVSINKLNDGTEMRVKGGYTSAQKYFKIKSLKRKGVFVSIKKGTETKVPNGFVSASGIFMKRQGKDRYPLKGIYGPALPQMFGNETVMNAMQKEGMEMYEKRLYHELERALGGN
>NZ_CP019721|1063084:1139493|1118563_1119253_+|WP_004693664.1|DBSCAN-SWA
MSEHILIIEDDLDIANIERDYLMVAGYDVTIMTNGTDGIEAALNTPVDLIILDVMLPEMDGFEVCRQIRDKVRVPIVMVTARLDDIDKIRGLGVGADDYIEKPFSPSVLIAKIKAMLAQYKRLTERDAMETNAIQSGEIRLDPKMMKVWVNEKEVHLKKKEFQLLEFLMRNRDIVFSKEELYSRVWGLDSYGDYATVAVHINRLREEIEDNPSDSKHIITVWGVGYKFV
>NZ_CP019721|1063084:1139493|1135013_1135793_+|WP_021147807.1|DBSCAN-SWA
MKSLKVLACAACLMGTVSGVGFAKDVQTIAGSMVVPNNVNIVSASKTNTRDFVEKQMQQNPSKSTMANMMAKEFFQNFGTNFDIYQLQGADKTGQKDAFVVAVDVKQIAQQVAKEKANDPMFIAAMAALDKGQIDPVTEQLLLGTINKQIPTSTTVVPLNGPINVSSRDSQKATIMPKTLKTLTVENAEQVHPVAGTKYQTYAASSRLLYADGNVQTPLYANAAFVLKPGKPVLYVGITTDVQRDYFKPIFDNAFKSIK
>NZ_CP019721|1063084:1139493|1138947_1139493_-|WP_077708650.1|tRNA|DBSCAN-SWA
MTKNITPIEIKNMDERSRDEYFMGFALKEAHKAYALGEIPIGAILVQNNTIISRHHNRRELDHDATAHAEVLVIREACDVLKRWRLTGCTLYVTIEPCPMCAGAIINSRIDRVVYGASDYKGGAVESLFNVLSHPGLNHEPELASGVLGDECSQIMKDFFKERRKTRRSTQEAEGSALEMR
>NZ_CP019721|1063084:1139493|1064398_1065145_-|WP_077708122.1|DBSCAN-SWA
MNFKDPKNILEFIKFQKQLLYRYKNYVKELMQKDYKKAAILAYWLRDYLGYIKNEKTFKPKQLITYKRGQIVFVNFGFRVGQELGGLHYAIVLDIKNSKNTSTLTVIPLRSKKDKNTSYQNLYMVPLGGVLSDLIDDKAKAMVKALNQEADDLAKKYPIDVIRTDKSLQSRVIKLRKQHKDAMAVLSYLDNLKSESMADIGQITTISKQRIKAPVRTTDVLTNIILPDELLNNLETKLKFLYFSCEKP
>NZ_CP019721|1063084:1139493|1104642_1104933_-|WP_077708175.1|DBSCAN-SWA
MAVFLVSYDLNKQGQNYTNLINAIKTYDAYIKCLHSQWLISTNDNIDSVYVYLSNKIDNNDLLLITPIVQPFYATLQSDVISWLKHEQNLGHIPTI
>NZ_CP019721|1063084:1139493|1103193_1103571_-|WP_077708173.1|DBSCAN-SWA
MTTNKGDRIKNLRINNKMTLEEVGEKIGVSKQTLYKYENNIITNIPSDKIEGLARVFNISPAVIMGWDKDDEQYYQDKEAAEYAEILHTRPEMRLLFSASREISKEEMQEVVNYIEFIKSRHKNK
>NZ_CP019721|1063084:1139493|1071462_1071627_+|WP_187658833.1|DBSCAN-SWA
MSAMTYKEKREFRRAAMAPQLADVIEGFIVGACFLYLVVGIFYWWITGEILVKW
>NZ_CP019721|1063084:1139493|1083276_1084359_+|WP_077708149.1|protease|DBSCAN-SWA
MNKFWSVKNFVNQDGTGQSELFLYGDISDTSWWGDEITPREFASDLASCNGNDLTMRINSGGGDVFAAQAIHNMIKAYTGKVTAHIDGLCASAATIIACAADKVIMPSNALYMIHNPSVFLGDSFDADGLTKMANYLASVKQTIANIYLSRSDVLTSEQVNTLMDDETWLTADEAKSYGLIDEVDTAITDKAVMNNGMVIVNKVSCKYSAKNEAKIKQFLTSKEKPMTENQFMASLKGLLGISTNEPAENAAVTAERERVEALNTLKGDNEVVNRLVDVAVKEGKTVNEVTPFISAVSDIPASDNKVVDQIRQLVIDQMESGADKVAPQGASTTETNDAVAKASAIDEVVAFANAKKGGK
>NZ_CP019721|1063084:1139493|1084710_1085760_+|WP_077708151.1|capsid|DBSCAN-SWA
MAIDFKDTFSLMQAVERMKTPASFLLDTFFPQVPAVATSKKIAVETRKRGRTLAPFVSRGASGVNVKRAGSKIALYEAPMMGPRTVIDPEQLDQRAFAENIVSTMTPAQRAAQMQAEDLSYLQGTIINRKNKMAADLLTTGKCKIEGYADDGETVQVDEIDFEFEQDITPTTTWDQAGADIYGDLKMASEKIQENAGIVPTVLVVGKNVEKYILDNASINKMLAIPNRENMSMFSFAPEYLSPQVRYVGRIMSLNIDVYAYLETYQDDEGKVKSFIGDDAAVLGVPGRGRQQHAAVTLLNDDNQFTTYAGIYVPYYYANKATQELTLSVYSRCVLIPETIDDWATIKTK
>NZ_CP019721|1063084:1139493|1073515_1073722_+|WP_077708135.1|DBSCAN-SWA
MRRGRPRKICSHSFGPAKSGALWVKTSCPKGKTSIKVFRGKTAGTLYWLKKEECEDCPAYSPTKIYAK
>NZ_CP019721|1063084:1139493|1109977_1110541_+|WP_077708182.1|DBSCAN-SWA
MEIIDVINARTSVRRYKKSSSVGEDIIQNLVALGMRAPSPKNRQPWQVVHVTGVEKKHFVNLGFQVLEQYKERKEHFGSLEISLKAMQTASDLLFVYNPYDHLSDYAQVWEKSDLQAIGAFIEHILLGAKAIGLGTLWMNDVYFMQSESKAFLNIPHDVQAIIAIGIPDESMYPRPRKSIDEVLIKR
>NZ_CP019721|1063084:1139493|1113391_1114567_+|WP_077708185.1|DBSCAN-SWA
MNILFVRLSYIGDVLHATPAARWIKEQYPDAKLHWIVTPSMAELLQGNPYVDKIIPWERDIYEAHSKKLHIPTMWRMWWDLKAKLEPYKFDVAVDVQGRLITGLVLLASGAPIRLGLGGTKELNWLFTNYKTKPSTEHVIKRYVEVAQLLTKAITEHANLDTSLNIDKYGIESSCSLNESNANMLYHMDFQVPTNLHSWAEEQWKSIDNDVSLHRGVVETPLRIGLVLGTSWATKEWPQEKWYSLIKSLQYRGNFVCLGGPKEATQYKPLLDSLTDEGIDKIVLNMLGKTTLQELGALIESCDVLVTADTGALHIALALNKPVVALFGPTDPKLWGPLTGTFKVLVNDELDCLGCRKRRCPKPDQYCMSGIDPVRVKKAIFELIGDTHGKV
>NZ_CP019721|1063084:1139493|1099971_1100364_+|WP_077708169.1|DBSCAN-SWA
MDKLAIINRIKRSYKSIRIAGIRPTGVLATRALVLVMLVPMILVVAQYVLSTIKGYVSPEENQLIDKGILIIDHIFVPSVLMTIVGLCGMFIDKNHNGIPDKLEEPNTLPMNRPGIQQLEDDINHDERGK
>NZ_CP019721|1063084:1139493|1110609_1111413_+|WP_077708183.1|DBSCAN-SWA
MKRIPLVTLLVLVLAMVVAGCGLLSQKTEPTSSVPPVKEVKMVHPTGIPVLMYHKVGDDKDNDAVIREDLFREQMKFLKDNGYNPLTMDQLYDYVVNGAAVPEKPVVLTFDDGYADTYSIVYPLMKEYGFPATVFINPGDVGTRLTWDQVREMHKNGITISNHGFQHIEMGQLSEAKQIENITKAQEALAKEVGIKDNPWFCYPYGDKNEFTDSASKKAGIKMGMAMKSGWAHTGDNPYNILRVWVGNAVDIKHFEERISTEHFTDL
>NZ_CP019721|1063084:1139493|1100364_1100940_+|WP_077708170.1|DBSCAN-SWA
MFRQITMDELKDLALDAYGQIEKAYYHWTGVKGGKHFTDYHINIDRAGTMWTDIEALTDYKEHTYMRNSNAVGIAIEACWDAVSENNLGSEPPTKEQLATMTQIMAVLTINAGVPLDLQHQMTHAEAADNRDGLDLYYLDPTGYPNNTYGPDSNVDRWDLLVCHEGDERWSGGDWLRGTARWWGAQWGSTI
>NZ_CP019721|1063084:1139493|1075290_1075743_+|WP_077708139.1|DBSCAN-SWA
MTEEEIQKKLGKHLFLKNITIPNITMHGDGKGEYEADLIYFNLKARVVTEIEIKVSIQDFRADFKKKRYHDHLHVGYLYYAVPQDLYEDHKDEIESLLGDAGLIVANISNNKKEDVRYIKRAKKRKDVKALNESEVINYLRIGCMKWVNR
>NZ_CP019721|1063084:1139493|1074048_1074822_+|WP_077708137.1|DBSCAN-SWA
MNHVTTLFNSNEFGELRTIIIENEVYFVAKSVATALGYKDTADAIRKHIDEEDKLRWQIADTGQKRETYLINESGLYSLILKSKMPSAKKFKRWVTSEVLPQIRKTGSYELNIPKTLPEALRLYADEVEAHNQSKAIIEQQKQQIAEYEPKVDYVDKILSSTNAMTVTQIAADYGLSAKALNKILHDAHIQRSVNGQWILYSDLMRKGYTKTKTHTYMTTDGRLECKTSTRWTQKGRLMIHELLKKLGINAVCEEVA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1063069:1063087	attL	NA	NA	NA	NA
WP_077708121.1|1063084_1064158_-|integrase	site-specific integrase	A0A0A8WIE1	Clostridium_phage	6.1e-30	29.8
WP_077708122.1|1064398_1065145_-	type II toxin-antitoxin system PemK/MazF family toxin	J7KDP1	Streptococcus_phage	6.4e-10	28.8
WP_077708123.1|1065215_1065749_-	hypothetical protein	NA	NA	NA	NA
WP_077708645.1|1065766_1066018_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_187658831.1|1066067_1067264_-	Abi family protein	A0A1Q1PVS3	Staphylococcus_phage	3.1e-14	27.7
WP_077708125.1|1067302_1067704_-	helix-turn-helix transcriptional regulator	A0A2I6PD82	Staphylococcus_phage	3.1e-11	36.4
WP_077708126.1|1067883_1068114_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_077708127.1|1068129_1068390_+	hypothetical protein	NA	NA	NA	NA
WP_077708128.1|1068376_1068949_-	hypothetical protein	NA	NA	NA	NA
WP_077708129.1|1069349_1069694_-	hypothetical protein	NA	NA	NA	NA
WP_187658832.1|1069855_1070011_+	hypothetical protein	NA	NA	NA	NA
WP_077708130.1|1069994_1070282_-	hypothetical protein	M9Q2L4	Clostridium_phage	5.3e-21	53.9
WP_077708131.1|1070471_1071137_-	hypothetical protein	NA	NA	NA	NA
WP_008715497.1|1071245_1071446_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_187658833.1|1071462_1071627_+	hypothetical protein	NA	NA	NA	NA
WP_077708132.1|1071692_1071980_+	hypothetical protein	NA	NA	NA	NA
WP_077708133.1|1072301_1073099_+	hypothetical protein	H7BW41	unidentified_phage	1.4e-18	39.0
WP_077708134.1|1073131_1073503_+	single-stranded DNA-binding protein	E5DV85	Deep-sea_thermophilic_phage	8.9e-13	36.3
WP_077708135.1|1073515_1073722_+	hypothetical protein	NA	NA	NA	NA
WP_077708136.1|1073796_1074024_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_077708137.1|1074048_1074822_+	phage antirepressor KilAC domain-containing protein	A0A0A8WIE3	Clostridium_phage	5.0e-58	47.1
WP_077708138.1|1074818_1075235_+	hypothetical protein	NA	NA	NA	NA
WP_077708139.1|1075290_1075743_+	MmcB family DNA repair protein	NA	NA	NA	NA
WP_077708141.1|1075991_1076336_+	hypothetical protein	NA	NA	NA	NA
WP_077708142.1|1076328_1076787_+	class I SAM-dependent methyltransferase	A8ATY8	Listeria_phage	8.6e-58	66.2
WP_077708143.1|1076844_1077342_+	hypothetical protein	NA	NA	NA	NA
WP_077708646.1|1077337_1077685_+	DUF4406 domain-containing protein	NA	NA	NA	NA
WP_077708144.1|1077681_1078107_+	DUF1492 domain-containing protein	NA	NA	NA	NA
WP_187658834.1|1078260_1078554_+	HNH endonuclease	NA	NA	NA	NA
WP_077708146.1|1078944_1079475_+	hypothetical protein	A0A0C5AN04	Bacteriophage	1.0e-14	36.2
WP_077708147.1|1079508_1081413_+|terminase	phage terminase large subunit family protein	A0A2K9V2Q8	Faecalibacterium_phage	1.2e-140	43.4
WP_060923706.1|1081421_1081667_+	hypothetical protein	NA	NA	NA	NA
WP_077708148.1|1081676_1083284_+|portal	phage portal protein	A0A2K9V452	Faecalibacterium_phage	4.8e-111	42.6
WP_077708149.1|1083276_1084359_+|protease	ATP-dependent Clp protease proteolytic subunit	A0A0C5AEN1	Bacteriophage	2.4e-37	30.5
WP_077708150.1|1084358_1084697_+	hypothetical protein	NA	NA	NA	NA
WP_077708151.1|1084710_1085760_+|capsid	major capsid protein	NA	NA	NA	NA
WP_077708152.1|1085774_1086011_+	hypothetical protein	NA	NA	NA	NA
WP_077708647.1|1086010_1086364_+	hypothetical protein	A0A2K9V315	Faecalibacterium_phage	7.5e-09	33.6
WP_077708153.1|1086351_1086885_+	hypothetical protein	NA	NA	NA	NA
WP_077708154.1|1086884_1087364_+	hypothetical protein	NA	NA	NA	NA
WP_077708155.1|1087373_1087601_+	hypothetical protein	NA	NA	NA	NA
WP_077708156.1|1087601_1089041_+|tail	phage tail protein	A0A059WKP9	Vibrio_phage	1.0e-120	47.3
WP_038125816.1|1089057_1089591_+|tail	phage major tail tube protein	A0A0C5AJ56	Bacteriophage	4.3e-24	37.9
WP_077708157.1|1089613_1089910_+	hypothetical protein	NA	NA	NA	NA
WP_077708158.1|1090079_1092416_+	hypothetical protein	A0A0C5ABJ2	Bacteriophage	1.4e-07	31.5
WP_060924349.1|1092408_1092612_+|tail	tail protein X	A0A0C5AEF4	Bacteriophage	5.2e-15	55.2
WP_077708159.1|1092615_1093776_+	hypothetical protein	A0A0C5AJ59	Bacteriophage	7.1e-48	34.8
WP_077708160.1|1093765_1094230_+|plate	baseplate assembly protein	A0A059WRL9	Vibrio_phage	1.6e-11	34.7
WP_077708161.1|1094239_1094716_+|tail	phage tail protein	NA	NA	NA	NA
WP_077708162.1|1094718_1095030_+	hypothetical protein	A0A067ZJ13	Vibrio_phage	3.0e-14	44.1
WP_077708163.1|1095026_1096148_+|plate	baseplate J/gp47 family protein	A0A0C5AEG2	Bacteriophage	2.7e-76	43.3
WP_077708164.1|1096144_1096804_+|tail	phage tail protein I	A0A0C5AJ63	Bacteriophage	3.8e-22	39.2
WP_077708165.1|1096813_1097710_+	hypothetical protein	A0A0C5AEQ0	Bacteriophage	2.2e-12	33.5
WP_077708166.1|1098001_1098853_-|integrase	site-specific integrase	A0A0E3Y5J2	Fusobacterium_phage	6.8e-32	33.1
WP_077708167.1|1098879_1099269_+	hypothetical protein	NA	NA	NA	NA
WP_174892239.1|1099270_1099411_+	hypothetical protein	NA	NA	NA	NA
WP_077708168.1|1099427_1099979_+	hypothetical protein	NA	NA	NA	NA
WP_077708169.1|1099971_1100364_+	hypothetical protein	NA	NA	NA	NA
WP_077708170.1|1100364_1100940_+	N-acetylmuramoyl-L-alanine amidase	NA	NA	NA	NA
WP_077708648.1|1101097_1101481_+	hypothetical protein	NA	NA	NA	NA
WP_077708171.1|1101650_1101968_+	hypothetical protein	NA	NA	NA	NA
WP_077708172.1|1102319_1103168_-	DNA damage-inducible protein D	A0A1W6JPJ7	Morganella_phage	1.9e-66	58.6
1101978:1101996	attR	NA	NA	NA	NA
WP_077708173.1|1103193_1103571_-	helix-turn-helix transcriptional regulator	A0A2H4J5K1	uncultured_Caudovirales_phage	3.6e-09	46.2
WP_077708174.1|1104151_1104628_-	DUF2321 domain-containing protein	NA	NA	NA	NA
WP_077708175.1|1104642_1104933_-	hypothetical protein	A0A1J0MFQ1	Staphylococcus_phage	7.5e-07	40.0
WP_077708176.1|1104976_1105192_+	hypothetical protein	NA	NA	NA	NA
WP_077708177.1|1105162_1105510_-	DUF2513 domain-containing protein	NA	NA	NA	NA
WP_077708178.1|1106324_1106966_+	hypothetical protein	NA	NA	NA	NA
WP_077708179.1|1107075_1108449_-	MFS transporter	NA	NA	NA	NA
WP_077708180.1|1108661_1108874_+	hypothetical protein	NA	NA	NA	NA
WP_077708181.1|1108980_1109772_-	carbon-nitrogen family hydrolase	NA	NA	NA	NA
WP_077708182.1|1109977_1110541_+	nitroreductase family protein	NA	NA	NA	NA
WP_077708183.1|1110609_1111413_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_004693677.1|1111424_1112363_+	phosphodiester glycosidase family protein	A0A1P8CWN9	Bacillus_phage	4.7e-10	29.2
WP_077708184.1|1112371_1113319_+	hypothetical protein	NA	NA	NA	NA
WP_077708185.1|1113391_1114567_+	glycosyltransferase family 9 protein	NA	NA	NA	NA
WP_004698343.1|1114553_1114880_+	hypothetical protein	NA	NA	NA	NA
WP_008602782.1|1115424_1116777_+	pyruvate carboxylase subunit B	NA	NA	NA	NA
WP_077708186.1|1117226_1118567_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	5.9e-22	25.6
WP_004693664.1|1118563_1119253_+	response regulator transcription factor	W8CYM9	Bacillus_phage	7.7e-34	35.9
WP_004698370.1|1119919_1121017_+	trypsin-like peptidase domain-containing protein	W5SAB9	Pithovirus	7.2e-10	31.5
WP_077708187.1|1121376_1121706_+	PadR family transcriptional regulator	NA	NA	NA	NA
WP_008602778.1|1121692_1122268_+	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_077708188.1|1122277_1122640_+	transcriptional regulator	NA	NA	NA	NA
WP_077708189.1|1122824_1123412_-	orotate phosphoribosyltransferase	NA	NA	NA	NA
WP_004698328.1|1123408_1124128_-	orotidine-5'-phosphate decarboxylase	NA	NA	NA	NA
WP_008602770.1|1124316_1124946_+	3'-5' exonuclease	A0A2I6PEZ7	Staphylococcus_phage	1.6e-14	30.1
WP_004698377.1|1124960_1125623_+	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_021147799.1|1125676_1126978_+	pyrimidine-nucleoside phosphorylase	A0A0H3UZD4	Geobacillus_virus	4.6e-112	51.1
WP_174892240.1|1126988_1127414_+	cytidine deaminase	NA	NA	NA	NA
WP_077708190.1|1127391_1128849_-	glycosyltransferase family 39 protein	NA	NA	NA	NA
WP_021147802.1|1128853_1129489_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_021147803.1|1129648_1131133_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	3.6e-20	27.1
WP_021147804.1|1131137_1131857_+	response regulator transcription factor	W8CYM9	Bacillus_phage	8.0e-42	39.6
WP_004698373.1|1131960_1132779_-	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_021147805.1|1132922_1133825_-	1,4-dihydroxy-2-naphthoate octaprenyltransferase	NA	NA	NA	NA
WP_021147806.1|1134067_1135012_+	hypothetical protein	NA	NA	NA	NA
WP_021147807.1|1135013_1135793_+	hypothetical protein	NA	NA	NA	NA
WP_021147808.1|1135925_1136297_+	RidA family protein	NA	NA	NA	NA
WP_077708192.1|1136298_1137546_+	serine dehydratase subunit alpha family protein	NA	NA	NA	NA
WP_012863974.1|1137657_1138845_-	MFS transporter	NA	NA	NA	NA
WP_077708650.1|1138947_1139493_-|tRNA	tRNA adenosine(34) deaminase TadA	NA	NA	NA	NA

Sequences of DBSCAN-SWA_4

Nucleotide sequences of DBSCAN-SWA_4

>NZ_CP019721|1802518:1810782|DBSCAN-SWA
CCTATGCTAATGCTTTGTATGCGTCATAACCTTTTTCTTCGATTTCACGTACAAGAGAAGCATCACCAGTTTTAACAATCTTGCCATTAATCAACACATGAACATAGTCTGGTTTTAGTTTTTGCAAGATTTGGTTATGATGAGTAATGATTAATACAGCATTTTCTTCGTTATGGAAACGTTGTACACCTTCAGATACGATACGAACCGCATCTACGTCAAGGCCAGAATCAGTTTCATCAAGAATAGCCAATTTAGGATTCAAAATGGACATTTGAAGAATTTCATTCTTCTTGCGTTCACCACCAGAGAAGCCTTCATTTACATAACGTTGCGCATAAGATAAATCAAAGGACAATTCATCCATTTTTTCTTTCAATTCTTTTTTGAAAGATAATGCACGTACATTTTCACCAGTAATTGTGGATTTAGCTGTACGAATGAAGTTTTCTACAGTAATACCAGGAATAGAAATTGGATTTTGGAAGGACATAAAAATACCCGCTTTTGCACGATCGTTTACTGCATCTTCCGTAATATCCTTACCATCAAAAATGATAGAACCACTATCTACTGTATATGTAGAGTTACCCATGATTGCATTAGCAAGTGTAGATTTACCAGCACCATTTGTCCCCATCACAACATGAATTTCACCTTTATTAATTGTTAAATCAATACCTTTCAAGATTTGTTTCTCTTCAACAGATACCTTTAAATCTTTTATCTGAAGTAATTCAGCCAAAATGTTCACTCCTTTTATTTGTATGTAACCATAAGAAACATACACTCGTTATATATAAAACGTATATACTGACACATATAAAAAGGCGGTACGCACTAACGTGAATACCGCCGTAATTCTCGCCAACTTAGCAAGTATGTGCATAACAATCTACACTCATTATACATTCTTATCTAAATGATAGCAAGATATTCCTACTAAAATATACAGGAATTAAAAGAATATCAAGTATTACATATATTGATAGGTTTTTATTAATATTAATTCTCATCCTATTCGATTCTCAATATTAAATTATAGGTTTGAAAAATCAAGAGTTCCAAATAAATCATCGTATGTTTCAGCACGACGAATTTGTGTAACAGATCCATCTTTATGTAGCAATAACTCTGCAGAACGTAATTTACCATTATAATTGAAACCCATAGAATGTCCATGTGCACCAGCATCGTGAATGATGACACGATCTCCAATATCAATTTTTGGCAGCTCTCGTTGAATAGCAAATTTATCATTATTTTCACATAAGGAGCCTGTTACATCATATACATGATCCTTGGGATCATTTTCTTTCCCCATTACGGTAATGTGATGATAAGAGCCATACAACGCCGGACGCATAAGATTTGCCATACAAGCATCTAAACCGATGTAATGACGATAAATATCTTTTTTATGAATAGCAGTAGAAACAAGATAACCAAATGGACCTGTTACCATACGCCCACATTCATAAGCCAATGCTACATCATTAAGTCCATTAGCTACTAAAATCCGATTATACGCTTCTTCTACACCCTTGCTTAATACGCGGAAGTCTACTGGTGTTTGTTCTGGTTTATAAGCTACACCTACACCTCCACCTAAATCAATAAATTCAACAGTGATACCAAGTTCTTTTTTAATATCTACAGCAAGATTAAAGCAAAGCTCTGCTGTACCAACTAAACCGTCAATATCAAGTTCGTTAGAAACAACCATTGTATGAATACCAAAGTGTTTTACACCTTTAGCTTGTAATTGTTTATACGCTTCAAATATTTGTTCGCGTGTCATACCATATTTAGCTTCTTCAGGAAGGCCAATAATTGTATTGCCCCCTTCCTTTAAAGAACCCGGATTATAACGCACGCAGAATGTATCTGGCAAAGAGCCATGATTTTTTTCTAAATATTCGATATGTGTAATATCATCAAGATTGATGATTGCACCCATTTCAAGTGCCTTTTTATACTCCACATATGGTGTGTCATTAGATGTGAACATAATATCATGGCCCGTAATACCCACTTTTTCACATAAAAGTAGTTCCGCTAAGGAAGAACAGTCTGCGCCAACCCCAAGCTTTTGTAACAAACGCATGATATACGGATTTGGAGTTGCTTTAACTGCAAAATATTGCTTGAATCCCTTATTCCAAGAGAATGCATTGATGAAAGATTTCATATTCTCAATAATTCCTTCTTCATCATAAATATGGAATGGAGTTGGATACTGAGCAATAATATTTTCTAATTGTTCTGACGTGAATGGAACTGTTTTTTTGTTCATGATAACCTTTCTACATAAATAAAAGACTCATCAGCCGATGAGTCTTTTATTCTAATTTCCTAATTATTTAAATAAAGCTTTATCTAAACTAAAGCGACCAGCACCAGCAAAAAATAACATAAGTGCACCAAAGCCTAATTGAGATGGGTAGTCCCAGCTAAAGAAACTACCATTCAAACTCACAATAGTCGCAGTTGCTAAAGTACCTACAACTAGAATAGCACCAATACGTGTAAATAATCCTACTGCAATGAGAATACCACCAATCATTTCTGCAAGTGCTGCCATAGTGCCTAACATCTCATAACCACCGGATACACCTAAAGGTGCTAACATAGTCCCTACTTTGTAGAGCCCTTCAGCTCCGCTAAGCCATTTTAAATAACCATGATAAAACATGGAAATGCCCAATGCAAGGCGATAAATCAATAAGCCAAAGTTTACATAATTAGGTTTACTTTTAAAAATAAAGTTCAACATAGTGATCCTTCTTTCAATTCAAATATAGCAAATCGAATAAATTCGATACATTAATTATACTATTAGAGAATAACTATGTCAATAAGACTCACTATTAAATTCTATAGAATTATATCATACATTGTATACAAAATCAATTTTATCGATGTAATCAACATAATATAGTCAGCTTAAATACAATCATAGTTTTTTTGAAATTTGAAATTTAAAACATTACACCCTTACAATAGATTAATTTATCAGTAAAAAATAATCCTAATGAATATGAAAAAATGTAATTCACAATTCATTAGGATTATTATATTTCTTATAAAATTAATTCTAAGCAGCTGATTACATCATACCGCCCATACCACCCATTGGAGGCATTGCAGGAACTGCTGCATTTTCATCTACCTTATCAGCTACGATTGTTTCAGTAGTTAATACAAGAGATGCGATAGATGCGGCATTTTGAAGGGCAGAACGAGTAACTTTTGCAGGGTCAACAATACCAGCTTTAACCATATCGATGTATTCTTCAGTCAAGGCATTGAAACCTACACCAGCTTCAGTATTTTTAACTTTTTCTACTACTACAGAACCTTCGAGACCAGCGTTGTATGCAATTTGACGAAGTGGTTCTTCTACAGCGCGTTTTACAAGGTTAATACCAGTTTGAACATCACCAGTAGCTTTCAATGTATTCAATGCAGGGATGATATCGATGAATGTAGTACCACCACCAGCTACGATACCTTCTTCGACAGCTGCACGGGTTGCGTTCAATGCGTCTTCAATGCGAAGTTTCTTATCTTTCATTTCAACTTCTGTAGCAGCACCTACTTCGATAACTGCAACACCACCGGACAATTTAGCTAGACGTTCTTGTAATTTTTCACGGTCGAAATCAGAAGTAGTTTCTTCAACTTGTGCACGGATTTGGTTAACGCGTTTAGTAATTACATCTTTATCACCTGCGCCATCAATGATTGTAGTTTCATCTTTAGTGATGCGAACTTGACGAGCTGTACCAAGATCTTCAAGTTCTACAGAATCAAGCTTACGGCCCATATCTTCAGTGATTACCGTACCGCCAGTTAAGATAGCGATATCTTCAAGCATAGCTTTACGACGATCACCAAAGCCAGGAGCCTTAACGGCTACAGCTTTGAATGTACCACGCAAACGGTTTACTACTAATGTAGCCAACGCTTCCCCTTCTACATCTTCAGCGATAATAAGAAGTTCTTTGCCTACTTTTACTACTTTTTCAAGTGTTGGCAACATATCTGCGATGGCACTGATTTTACGATCAGTGATCAAGATATATGGGTTATCCATAACAGCTTCCATACGATCAGGGTCAGTTACCATGTAAGGGGAAATGTAACCACGATCAAATTGCATACCTTCTACTACATTTAATGCAGTTTGCAAACCTTTGGATTCTTCAACAGTAATAACACCGTCATTACCAACCTTTTCCATAGCTTCAGCAATCAAACCACCGATTTCTTCGTCAGCAGCAGATACACTTGCAACTTGAGCAATTTCAGCTTTACCAGAAACTTTAATAGAGCGTTTTTTGATTTCTTCAACTAAAGTTTTTACTGCTGTTTCAATACCTTTTTTCAAAATCATTGGGTTAGCACCAGCTGCTACATTGCGCATACCTTCTTGAATCATAGCTTGTGCCAATACTGTGGCAGTAGTAGTACCATCACCTGCTACGTCGTTAGTTTTAGTAGCAACTTCTTTTACCAACTGAGCACCCATATTTTCAAATGGATCTGGAAGTTCGATATCGCGAGCAATAGTTACACCATCATTTGTAATTGTTGGGGAACCGAATTTTTTATCCAACACAACATTACGACCTTTTGGACCTAATGTAACTTTTACAGCATTTGCTAATTGATCTACGCCACGACCTAAAGCACGACGAGCTTCTTCATTAAACAAGATTTCTTTTGCCATATGTATTACCTCCTAAATAGTAACACTATCCAATGTAACGAAATATATGTGCCCTTAGGCAATATAGAATGCATCATCAGTTTTTATAGTCATATAGACTATAAATTAGCGATTATAATACTGCTAAAATATCGCGTTCGCTAACAATCAAATGAGTAGCACCATCAATTTCTAATTCGCTACCAGCATATTTTGCGAACATAACAGTGTCGCCAACTTTAACTTCTGGAGCTACACGTTGACCATTGTCATATACTTTACCAGCACCTACAGCTACAACTACACCTTCTTGAGGTTTTTCTTTTGCTGTATCAGGAAGGAAGATACCACTTTTAGTTTTTTCTTCTTTTGCTTCTAGACGGATAAGAACGCGGTCAGCTAATGGTTTTAACATATAATGTCACTCCTTTTTACTAGTTAATCTCCATAATTTATTAGCACTCTAACTCATCGAGTGCTAATTACAAGTATTATTATAACCGAAGTTAAAATAATTGCAAGTACTAATTTTGATTTTTTGACTTTTTAGATATTATTTGACTTATTAGACTGTTTAATAATGAGATTACATGTTTCTATAATAGATATTTGTTTATTCATACTTAAGGTGCGAATGCGATTATACGCTTCCGCTTCAGATATAGAATATAGTTCCATTAATATACCAGTTCCCTTTTGAATGATTTTACGATCTTCTAATGACTGTTCTAACTCAGCCATCTTTTCGCGCAACTGAGCATCACTTTTATAGCGACCTAAAGCCATCTCTAAGGTAGGAACTAACTGTTCCTCCCGTACTGGTTTAATTAAATAGCCATATACACCAGAATCTCGAGCCTTATCGATTAAATCTTGCTGGCTATAACTTGTTAATAATACTACAGGTGCTTCATGGTGAAAGCCAATTTGACGTGCCGCCTCAATACCATCTAATTCTGGCATCTTAACATCCATCAATATAATATCTGGCTTATGTTTTTTACAAAGTGCTAAAGCTTCAACACCATTTGTACCTTCTGCAACGACTTCATGACCACAAGACTCAATAATATCTCGTAAATCCATACGTATTAGGGATTCATCATCCACGATTAAAACGCGCATTTATGCCTCCTTTTTCATATATATCGTCACCAATACACCTGTTCCAGTATTTTCTATGGATAAACTTCCTTTTAATTCATGAGTAACTAAATTATTAATAATTGTTAAACCTAACCGTTTATTAGACGAAACAGAAAAATCACTAGGCAATCCTTTTCCGTTATCTGTAAAAGCCAGTTTAATTGTACTACCTGCATTAGTAACTGCTAGATGAACATTTCCACGATTCCCGTCTAACCCATGTTCTAAGCTATTCGTAATCAATTCATTAATAATAAGAGATACATAACTTGCCATATGAGAAGAAATTAGCATATCTTCGCCACTATAAGTAAAAGTAACCTCTTGGTCTTGTCGCACCATACTCATACGCAACAAACGACATAATTCATCGTAAATTGATCGTATACCAATATAATCCTCATCGTAATGAGACACTATATCGTGAACTAGAGCCATGCTCTCGATGCGATTAATCCCCTCTTGGAGTGCTTGCTTTACATCTGGCAAGCTAGAGCGTCTCGCCTCCATACGCAATAACCCTGCTACAGTTTGTAAGTTATTTTTTACACGATGATGAACCTCTTTGATAATGGAATTTTTAACCAATAATTCTTGTTGCTGTTTACTTTCACGAGTACAATCATGAAGAACTAAAAAGCACCTCGTTTCATTGCGCCCCATAGCAATAGGAATCATGTGCTGACGAATTACCATATCTTGATAGATTTCTTCATTTATACGTATACTTCTATCTAATAATACCTGCTGTATAGCGGACATCTTTAAGGTACTGCTAAAAATTGATGAACCTACCAAGCGACGATCAAAGCCTAATACATCTACTAACTTCATAGCTGCATCGTTAGCATACAGTATTTTATAAGTGTCGTCGAAAATAATTAAACCATCAAAATAGGACATGGGTTCGTAAGACAATATTTGTTCATCAGTAGCCGTCAGCATAAGACGTTGCATCGTATCAGACAAAAGGTATTCTTGCTCATATTGTTCTGCCTTAATAGATGGTGATAATGTAAAAGATATCCCCCCAATAATACGACCTCCGTTGTCTACGATAGGAAAGACATATTGACGCTGCTTGTCATCTAACCCGATAAGTGGTTGACCATCTTTCATCATAGCATGCCACGTATGACTGCCTTTTAAATGACGTGTAGTAATCCCTTGATCACTGCGTTCTATGCATAGCATATCTGCACATTGTTGTAATCTCTCACCTTGTCCTGTCTCTAGTAGGGGTGTAAAAATCTGTATCCTTTGACGAGTTAAAGACTCGCCAAAGGATATGAGTTTACTAATATGCTCAAGTAATGAGGTTTGTAATGGTCCTAATGGTGTTCTATTTAAAATATCTTGACCAATATCCACGATTAATCCTCTTTCCAAGATACGTATCCAATTTCAACACTAGGCTTTGCATTCAATGTTAAATCGCCAAATTTTCCAGCCTGCGCCATATAATAAGCTCGACATCCAATCATGGCAGCATTGTCAGTAGACAATATTTTATGTGGTTTGTAATAAGTAAAACCTTCTTCTACACACATAGCTTCTAAAGCCTTTTGTAATCCTTTATTAGCTGATACACCGCCAGCAATAGTAATACGACTTTCACCTAAAGTATGTGCGGCATCTTTCATCTTTTCTACTAACACATCTACGATGGCCTTTTGAAACGATGCAGCCACATCAGCTTGATTGATAGGCTCATTCTTTTGTTGCTTACTATTTAAATAGTTTAAAACTGCGGATTTCAAACCACTAAAGCTAAATTCAAAATTACCTGGTTCACTTAAAGCCTTTGGAAATTCAATAGCCTCTGAATTCCCTTCAGTGGCAAGGGCATCGATATGAGGACCCCCTGGATAAGGAAATCCCATAACCCGTGCAATCTTATCAAAAGCCTCACCAGCTGCGTCATCTCGTGTTTGACCAAGAACATCAAAATCTTCATATCCTTTTACATGTACTAACATGGTATGACCACCAGATACAACAAGACTTAAAAACGGAGGCTCCAGTTCTGGATTAGCTAAAAAGTTAGCAAAAATATGACCTTCCATATGGTGCACTGGCACCAAGGGAATCCCTGTAGCAAAGGATAACCCTTTTGCAGCAGCTATACCAACTAATAAAGCCCCTACAAGACCTGGCCCATACGTAACACCAATATGATTGATATCTTGTAGAGTCACATTCGCATCACGTAATGCTTGGTCTATAACAGGTATAACTTGTTCTATATGATGACGTGATGCAATTTCAGGTACAACGCCACCAAATTTTCTATGTATTGGTACTTGGCTTGAAATAACATTAGACAAAACGGTGCGCCCGTCCTTAAGGACAGAAGCAGAGGTTTCATCACAGCTACTTTCCAAGGCTAATGTGTATATACTCAT

Protein sequences of DBSCAN-SWA_4

>NZ_CP019721|1802518:1810782|1804876_1805293_-|WP_004696040.1|DBSCAN-SWA
MLNFIFKSKPNYVNFGLLIYRLALGISMFYHGYLKWLSGAEGLYKVGTMLAPLGVSGGYEMLGTMAALAEMIGGILIAVGLFTRIGAILVVGTLATATIVSLNGSFFSWDYPSQLGFGALMLFFAGAGRFSLDKALFK
>NZ_CP019721|1802518:1810782|1809750_1810782_-|WP_077708478.1|tRNA|DBSCAN-SWA
MSIYTLALESSCDETSASVLKDGRTVLSNVISSQVPIHRKFGGVVPEIASRHHIEQVIPVIDQALRDANVTLQDINHIGVTYGPGLVGALLVGIAAAKGLSFATGIPLVPVHHMEGHIFANFLANPELEPPFLSLVVSGGHTMLVHVKGYEDFDVLGQTRDDAAGEAFDKIARVMGFPYPGGPHIDALATEGNSEAIEFPKALSEPGNFEFSFSGLKSAVLNYLNSKQQKNEPINQADVAASFQKAIVDVLVEKMKDAAHTLGESRITIAGGVSANKGLQKALEAMCVEEGFTYYKPHKILSTDNAAMIGCRAYYMAQAGKFGDLTLNAKPSVEIGYVSWKED
>NZ_CP019721|1802518:1810782|1803556_1804813_-|WP_008714049.1|DBSCAN-SWA
MNKKTVPFTSEQLENIIAQYPTPFHIYDEEGIIENMKSFINAFSWNKGFKQYFAVKATPNPYIMRLLQKLGVGADCSSLAELLLCEKVGITGHDIMFTSNDTPYVEYKKALEMGAIINLDDITHIEYLEKNHGSLPDTFCVRYNPGSLKEGGNTIIGLPEEAKYGMTREQIFEAYKQLQAKGVKHFGIHTMVVSNELDIDGLVGTAELCFNLAVDIKKELGITVEFIDLGGGVGVAYKPEQTPVDFRVLSKGVEEAYNRILVANGLNDVALAYECGRMVTGPFGYLVSTAIHKKDIYRHYIGLDACMANLMRPALYGSYHHITVMGKENDPKDHVYDVTGSLCENNDKFAIQRELPKIDIGDRVIIHDAGAHGHSMGFNYNGKLRSAELLLHKDGSVTQIRRAETYDDLFGTLDFSNL
>NZ_CP019721|1802518:1810782|1805626_1807252_-|WP_077708474.1|DBSCAN-SWA
MAKEILFNEEARRALGRGVDQLANAVKVTLGPKGRNVVLDKKFGSPTITNDGVTIARDIELPDPFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAMIQEGMRNVAAGANPMILKKGIETAVKTLVEEIKKRSIKVSGKAEIAQVASVSAADEEIGGLIAEAMEKVGNDGVITVEESKGLQTALNVVEGMQFDRGYISPYMVTDPDRMEAVMDNPYILITDRKISAIADMLPTLEKVVKVGKELLIIAEDVEGEALATLVVNRLRGTFKAVAVKAPGFGDRRKAMLEDIAILTGGTVITEDMGRKLDSVELEDLGTARQVRITKDETTIIDGAGDKDVITKRVNQIRAQVEETTSDFDREKLQERLAKLSGGVAVIEVGAATEVEMKDKKLRIEDALNATRAAVEEGIVAGGGTTFIDIIPALNTLKATGDVQTGINLVKRAVEEPLRQIAYNAGLEGSVVVEKVKNTEAGVGFNALTEEYIDMVKAGIVDPAKVTRSALQNAASIASLVLTTETIVADKVDENAAVPAMPPMGGMGGMM
>NZ_CP019721|1802518:1810782|1807777_1808356_-|WP_077708476.1|DBSCAN-SWA
MRVLIVDDESLIRMDLRDIIESCGHEVVAEGTNGVEALALCKKHKPDIILMDVKMPELDGIEAARQIGFHHEAPVVLLTSYSQQDLIDKARDSGVYGYLIKPVREEQLVPTLEMALGRYKSDAQLREKMAELEQSLEDRKIIQKGTGILMELYSISEAEAYNRIRTLSMNKQISIIETCNLIIKQSNKSNNI
>NZ_CP019721|1802518:1810782|1807364_1807646_-|WP_077708475.1|DBSCAN-SWA
MLKPLADRVLIRLEAKEEKTKSGIFLPDTAKEKPQEGVVVAVGAGKVYDNGQRVAPEVKVGDTVMFAKYAGSELEIDGATHLIVSERDILAVL
>NZ_CP019721|1802518:1810782|1802518_1803262_-|WP_004696035.1|DBSCAN-SWA
MAELLQIKDLKVSVEEKQILKGIDLTINKGEIHVVMGTNGAGKSTLANAIMGNSTYTVDSGSIIFDGKDITEDAVNDRAKAGIFMSFQNPISIPGITVENFIRTAKSTITGENVRALSFKKELKEKMDELSFDLSYAQRYVNEGFSGGERKKNEILQMSILNPKLAILDETDSGLDVDAVRIVSEGVQRFHNEENAVLIITHHNQILQKLKPDYVHVLINGKIVKTGDASLVREIEEKGYDAYKALA
>NZ_CP019721|1802518:1810782|1808356_1809748_-|WP_077708477.1|DBSCAN-SWA
MDIGQDILNRTPLGPLQTSLLEHISKLISFGESLTRQRIQIFTPLLETGQGERLQQCADMLCIERSDQGITTRHLKGSHTWHAMMKDGQPLIGLDDKQRQYVFPIVDNGGRIIGGISFTLSPSIKAEQYEQEYLLSDTMQRLMLTATDEQILSYEPMSYFDGLIIFDDTYKILYANDAAMKLVDVLGFDRRLVGSSIFSSTLKMSAIQQVLLDRSIRINEEIYQDMVIRQHMIPIAMGRNETRCFLVLHDCTRESKQQQELLVKNSIIKEVHHRVKNNLQTVAGLLRMEARRSSLPDVKQALQEGINRIESMALVHDIVSHYDEDYIGIRSIYDELCRLLRMSMVRQDQEVTFTYSGEDMLISSHMASYVSLIINELITNSLEHGLDGNRGNVHLAVTNAGSTIKLAFTDNGKGLPSDFSVSSNKRLGLTIINNLVTHELKGSLSIENTGTGVLVTIYMKKEA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004696035.1|1802518_1803262_-	Fe-S cluster assembly ATPase SufC	G9BWD6	Planktothrix_phage	1.9e-09	25.4
WP_008714049.1|1803556_1804813_-	diaminopimelate decarboxylase	NA	NA	NA	NA
WP_004696040.1|1804876_1805293_-	DoxX family protein	D2X5Z2	uncultured_marine_phage	3.5e-05	33.9
WP_077708474.1|1805626_1807252_-	chaperonin GroEL	A0A219YK78	uncultured_virus	1.6e-159	56.8
WP_077708475.1|1807364_1807646_-	co-chaperone GroES	A0A221S3C8	uncultured_virus	2.0e-17	52.7
WP_077708476.1|1807777_1808356_-	response regulator	Q6XM27	Feldmannia_irregularis_virus	2.3e-07	28.7
WP_077708477.1|1808356_1809748_-	sensor histidine kinase	NA	NA	NA	NA
WP_077708478.1|1809750_1810782_-|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	1.0e-69	43.4

Sequences of DBSCAN-SWA_5

Nucleotide sequences of DBSCAN-SWA_5

>NZ_CP019721|1974848:1985379|DBSCAN-SWA
ATTACACAAAGAAGAAATCATTTTGTTCTGTGAAAGCTTTCACAGGAACAGCAAGCCCTGCAGAGATTAAATAGTCACGTAAACCATGTGCCACTATAGACTCAGTTCCAAAATGCCCCGCATCAACTACGAGTAAGCCTAATTCCTTAGCCATTTGCGCCTCATGATACTTCACATCACCTGTAATATAGGCATCTACATGTAACCGGGCAGCATCCTTAATAAATTCTGCACCTGCACCAGAGCATAAAGCAATGGATTGAATCGCTTTCGGCACAATACCAGCAAAACGAATGTTAGCATCAGGCAACGCTTCTTGTACCCACTCACGGAAAGAATCTAAGTTTAATGCATTAGGCAAGCGACCTACCCGTCCTAGATATTGAGTTGAACTAGTAGGCTCGACTATATTCAAAACCTCATAAGCAACTTCTTCATATGGATGAGCAGCTTTCATAGCCGCTACGACTTTGCTTAAATGCGTACCATCAACGATAGCATTCACTTGTACCTCAGGAACCACTGTCAAAGCACCAGCTGCCCCAATGACAGGATGAGAATCTTCATTACCAACAAAGCGTCCTTCCCCATGGATACTGAAACTGCAATGCTCGTAATTACCAATTCGGCCTGCCCCTGCATCACCCATCGCCAATCGAACCGCATCAGCCGAGCTTTCAGGTACAAAAGTGGTCACCTTATAAAGCGCCTCTTCACCAGTTTTAATGAAGCCCTTAATATCTATAAGTCCCAATTGCTTCGCCAACATATCATTTAGACCGCCTGGTGCGATATCAAGATTTGTATGAGCACTATATACGGCAATCTTATGTTGAATCAGCTTATTAATCGTACGCCCATGAGCAGTATCACATGATATCTGTTTCAACCCTTTAAAGATTAATGGGTGGTGGCTAACAATTAAATTACAATTTTGTTCAATAGCATATTCTACGGTTTCTTCTGTTACGTCTAACGTAGTCACTACACCTGTAACAACTACATTCCGATCGCCCACCATTAAACCTACATTATCCCAAGACTCTGCATAAGAACGCGGTGCTAATTGCTCCATCAAGGTAATAACTTGTTGAACCGTTATCATACAACTCACTTCTTTCTATTTATTCTCTAAAAGATTACGAAGAAAATTAACTTCCTGCTCTAAATCCTGATATTTATCAGTATGATTTAATTTCTCTGTCATATCATCTAATGCACATTGTCGTTGATATATTAAATACTCTATATATTTCATCCAAAGTGGTGGTCTATCTTGTTCCAATAAAGCCCCTACAGACCACAACAAGGAGTCTTCCGGTAACGATTGATAAACATCTACATATTCAGTCATACCTGTATAAGCTTCCACGCAGTCATTGCGCACGGCTAAAAATGCTGTATAGAGCTTACCAGCATCTTCTACGATAATTTCTAGAACAATAACATATCCCTTTTGAACCATATATTGACGTAATTCTTTTTGTCCATTCTGTGGTTGGAGTACATAGAACTCTAATGGTTCTGGGCCTGCATCTACAATATCTCGCATTAAAAATCCACCCATACCACAACAAATGGCGCCGTTCAACTCGCCCTTTTCTGTCACTTTAAGACCATCGCCTAAACGACAATCTACTTTATCGGCTAGTCCACAAGACTCAACATATGATCTTGCAGACTCTAACGGACCTTTATGTACATCACCGGCAATGACATATTCAGCGCGTTGACGGTTGATGAGCTCTACCGCTAAATAGCCATGATCGGTACCGATATCGGCAATGGCATGAGCCTTAGGTACGATTGAGAATACCGCTTCTAGGCGGTCCATCATAGGTCTAGGTTCCATAACTTCCTCTACTATTACTAATCATTTATTCTTAATTACTAATTCTTGATTATTTTCTTACTTATTTGTTCTCGTTTATATAGCTCTAAACACAATACTATTCTGAAATAATCTCTATTATGTTACCTCAAAATGAGCTACATATAAAAATAACCGTCCTTGAAATCTCAAGGACGGTAGATATCAACATAATGGTGGGCCCACCTGGGTTCGAACCAGGGACCGACCGGTTATGAGCCGGTTGCTCTACCCCTGAGCTATAGGCCCTCAGTTAGTTTCTAGCTTATTAATTATACCGAATAGACTATCATTTAGTCAAGGAAACTCAAATCTTAAGACTGTTTCATTAGCATAAAACGGTGAATCATATGATCTTCGTTAAATACGCCTTTAGTAGTTAGTGTAGTCGTTTGGCTATCTGTAGATTTAATGCCTCGTGCACTCATGCAGCTGTGCGACGATATAATGTGCACAATAACATCATTAGACCCTGTCGCTAAAGAAATTACTTCCGCAATATCTTCACCAATTTTTTCTTGCAATTGTAAACGCTTGCAACACATTTCAGCTATGCGAGGAATCTTAGATAAACCTATGACACGACCTTTTGGTATATACCCAATACTGATACTCATATCATACATCAATGCCATATGATGTTCACAATGAGAGAAGCAAGTAATATCCTTTACTACTACCATTTGATTTGTATCTACAGCGAAGGTTTTACCATACATTTCTGCAATTTCAGCATTTGTATACTGAATGCCTTCATATACCTCTTCCATCATTTGAGCTACCCGTTTCGGTGTTTCTAACAAACCGTCCCGATTAGGATCCTCACCTAGTGCTTCTAACAACTGATATATAAGCGATTCTATTTTTTTTGTATCCATATTTACCCCTTTATATCAAGATTCCATCAGATCCCATATCATACTATGCATAAAAAAAGATACTGACACTACACATCCTAATAATACTATACACCCTTTGTATCTGGATCCCAGACAAATTTATGGATTTGCAGTTGAAATCGTACATTTTGCAAATTATATGCTTTCATATAATCGATAATCAATACCGCTTCAATCTGTCCCCATACAGGCGATACATATATTTGAGCCGCTGTAGGATATTGGTCAATTATGCGACGCATACAATCCAAATCTTCTGGAGAACCAACGACAAACTTGATAAGATCTCGTTCTGTAGCCACCTTGAATATGTCTATATTCATAGACTCTTCGGCTAAAGAAGACGGTGTTTTATAATCGTAGGTAAACCACACATTATCTCTATGAAAACTCGGTATAATCGTGCCATTTGTTTCAATATTGAAATCATAAAGGCTATTATTAAGCATCTCTCGTTTATCAAATTTATCTATATCAATAATACAAGTTGAACCAGCTTGACCTGATGTATTATCCTGCATTGTTTCAGCCTTCCGACGATTTAACTCATCGATTAGCTCTACTACAGCGGCTTCTTGCAATAAGGGCTCCCCACCAGTAATAGTAATGCGATGATTACCTAAGCTTTCAATAACATCAGCCACCTCAGCTACAGTCATCTCTGTGAAAATACTATCAATGCCGTAACTATAAGTCGTATCGCAATAGGAACAGCGAATATTGCAATCATGAAGACGTAAAAATGTAGTCAGCAAGCCTTGCCGACTACCTTCCCCATCAATAGAGGCAAAAATCTCAATCACGTTCATAAACAGCTGTGTTCCCTTCAGATTCTTGAACCTCTACTTTAAAGCATTTTGGGCCCAATTCATCAGCAATCCATTTTGCCATATTCTCCGCAGTGGGATTAATGTCACCTAGTACATCGTTGATATGGCGATGATCCAAGCGACCATGAATTTTTTCTTTAATAATCGTAAAGTCGATGACCATCCCGTTATGATCTAACTCTTCAGAGCGTGCATGAACTGTAATAATCCAGTTATGCCCATGAAGATTTTGACATTTACTCGGATAATCTAGTTTTAATTGATGAGATGCACTCACCTCTAACCGTTTAGTAACTGTAAACATTATATCTCCTATCTATTACATAAGCTTTCAACTTATATCTATTACATAAGACTTATCGCTATTACATGAAACCCTTGTCTATTACATAAGTCTTATCACAAAATATTTTTTATTGTAAGATATTATTATTTTTTATTATAACACAAAAGGGTTGTAATACAGTGCTATACAACACTGCATTACAACCCTTAAGAGTTTCAAAATATTATAAGAAGTCTTTGATTTTATCACGTTTACCGCGATTGCGCAATTTAGTAAGCGCTTTACCTTCAATCTGACGAATACGTTCTCTTGTTACATTGAAATGTTGACCAACTTCTTCCAATGTACGAGGCTTACCATCCTTCAAACCAAAACGTAAAATCAAGACTTGTTGCTCACGATCAGTCAAGCATGTAAATACATCTTCAATCTGCTCTTGCAATAAAATGTAGCTAGCTGCATCGTCTGGAGCAATTGCATCTTGGTCCTCGATGAAGTCCCCTAAATGGGAATCTTCCTCTTCACCAATCGGAGTTTCCAAGGATACTGGCTCTTGAGCGATTTTCTGAATTTCACGCACCCGCTCTACAGTAATTCCCATACCTTCAGCAATTTCTTCTGGCAATGGCTCACGACCCTTGTCTTGCAACAATTGTCTAGAAATACGAATCAATTTATTAATTGTTTCTACCATATGTACAGGAATACGAATCGTACGAGCTTGGTCTGCAATAGCACGCGTAATTGCTTGACGAATCCACCATGTAGCATACGTAGAAAATTTATAACCTTTAGTATAATCGAATTTATCTACCGCTTTGATTAGACCTAAGTTACCTTCTTGGATTAGATCCAAGAACAACATACCGCGACCTACATAACGTTTTGCGATACTTACAACTAGTCGCAAGTTAGCATCTACCAATTTTTTCTTTGCCTTTTTGCTAAGTTGAATATCTTTATATGTAGCATCCTCTTGAGCACCAGCTTCAATTTGCTTAGCTAATACGATTTCTTCATCAGCTGAAAGCAATGGCACTCGACCAATCTCTTTTAGGTACATTCGTACAGGGTCATCGATATTAACACCAGAATCAACACTTAAATCGATAGCAATTTTTTTCTCGCTAGAAACTTCGTCTTCATCTTCATCCGTTTCAATTGTATGATTATCTGTATCATCAGCATCAATATCTGCCACAATCTCAACATTCAATTTACCCAAAGTCGTATAAATATCATCTAATTGTTCCGCAGTAATTTCCGTCTGCTCATGAAGAGCATCTGAAATCTCGGATTGTGTCAACACACCGCTCTTACGGCCTTTTTCAAGAAGTTGCTCAACAATCTCCTCTATTTGACTTTTTTGTACTTTCTTAGCCACAGCGCTCTCCTTTTTAACCATTAATGATTTACTTAGACCATTCTCTAATTAAATTCTGTATTTCCTGACACTTATGTAATTCGCTAATAAACGTCGAATCTCCTGCTCGTTTTAATTGATCCGCCATAATCGAATGCGCTTTATACTGTTCACGCAATGAATGGAGCCTTATCTTGCGGATTAATGCAGGCACTTGTACCTTATATTCATCGTCACTCATGACGACCAACCTAGAGTAAATATCGTATTCTTGAGAAGATAAAACAGATTGAATTGCAGTTTCATCTAGACGACCTTCGGACTTATACAAGGTGAATAGCTTTTCTATTATACCTCGATATTCAATTTTTTCAAAGTCCTCTAATGGCAAATAGCTCATCATATGTTGTAATACTTCGCCATTTGTGAAAGCTAAGGATAATAATTTTTCCGCATCACCCCTTGGTAAATCCTGTGTTGGCAAAGGTGTCGATGCCGTATCCACTAATTCAATTTGTCCTTTTTTCACATAATCTCTAAAGTATCTAAAAATAGTACTATTATCAAGCCATAATGGCAATGCCAATGTTTTTAAAGCATCATCTCTCTGCGTTTGACTATCTATATTTGCAATATATGGGAAAACATCTGCCATAACAGCCTGCTTTCCTTCTGTATCATTTGTATCGTGTTTAATTAAAGACTCACTTAATAGATAATCAAGAGGCTTAACAGCTTTAGCAACTAACTCCTTAAATGCCTGCCCCCCATGATTACGCACATAATCATCTGGATCTTTGCCGTCTGGCATAGCAAGGACACGCACCTTAAAATCCGTATTTTGCAATAATTCAATAGCTCTAGCAGCCGCTTGACGACCAGCACCATCCATATCATAAGCTAACACGATTTCTTCAGCCTGCCTCATCAAGATATGTCCATGATCTCTTGTATAAGCAGTCCCCAATGATGCGACTACATTAGTAACACCATGATTATGAGCAGATATAACATCCATATAGCCTTCTACAAGAATAGCTTGTTTTTCCTCACGAATAGATTTATAAGCCTTATCAAAAGCAAATAGAAGTTTACCTTTTTCAAAGATTGATGACTCTGGAGAGTTTAAATATTTTGGTGTACTATCATCCATAACGCGCCCACCAAAAGCAACTACTCGCCCTTTACCATCCATAATGGGGAACATAATTCTATTTCTGAAGAAGTCATAAAATTGACCCTTTTGATTCTTTCGGACAAGATTCAACTCCAAGAGAATGGAATCATCAATACCACGGTCATGAAAGGCACGATATAACTTATCCCAACCATCAGGAGCAAAACCAAGTTTAAATTGTTCTATGGTTTCTTGTGTGAGCCCCCTCTTTTTCAAATAATCTAATCCCACTTTACCAATAGACGTTTGAGTGAGACAGTTATGGAAAAAGGTGGTTGCTAAATCAGAAGCTTCATACAGTTTTTTACGTCTTTCATCTCTAGCTCTTTGCTCAGGTGAAAGTTTCGCCTCTGGCAATGGAATATTAGCTCGATTAGCTAGCCGTTCTAGGGCTTCTACAAAGGTTAAATGCTCTAATTCCATAAGAAATTTAATAGCATTTCCTGATGCATGGCAACCAAAACAATAATAAAAACCCTTTTCAGGAGCTACGCTAAAGGATGGCGTTTTTTCATTATGAAATGGACAACAACCCCAATAGTTCTTGCCGCGTTTCTTTAAAGCTACATGCTCGGATACAACTGACACGATATCATTAGCATCTTTGATTTGTTCAATCAACTCATTTTCAAAATATCGGCTCATAGCCAACGCCTCCTTCCCCATATATATATTAATTCTATATACAAATAAAAAATCCTCTATTTGTAAAGCATTTTAATCAATTAAATTATAAAAATAATATAAAAAAGCTTGATACGAATCATAGGAATCATCATCTACAATGTAATGTACATGATGATTTCTATACGCCGTATATAGCAATATGTAATTACCGAAACTTTGATAACAATAGGCTGCAATGAAAACATTGCAGCCTATACTTATCGCTTATAGCATATTATTTTGCGTAATCCACAACGCGAGTTTCACGAATAATTACGACCTTAATTTGGCCTGGATATTCAAGTTCTGACTCGATGCGTTTTACGATATTCCGAACAAGTAATGTAGACTCAGCTTCATCAATCTTATCCGGCTTTACTACAACGCGAATCTCACGACCGGCTTGAATAGCAAAACATTTTTCAACGCCTTCGAAGGATTCAGCGATTTCTTCCAATTTAGATAAACGTTTTAAGTAGTTTTCTAATGTTTCTCGACGTGCTCCTGGACGGGCAGCGGAGATAGCATCAGCGGCAGCTACTAATACAGCTTCTACTGTTTGGAACTCTTCATCACCATGATGAGCACCAATACAGTTAATTACTGCTGCACTTTCACGATATTTACGAGCCACATCAACACCGATTTGAACATGAGAACCTTCAAGTTCACGGTCTAATGCTTTACCAATATCATGAATCAAACCACCTCGTTTAGCCAAAGTTACATCACAGCCTAGTTCAGCTGCCATTAAACCTGCTAAATGAGATACTTCAATGGAATGTTTCAATACGTTTTGACCATAACTAGTACGATATTTCAAACGGCCTAAAATCTTAACAATTTCAGGATGTAAGCCGTGAACATCAGCTTCAAATGTCGCTTGTTCACCAGCCTCTTTAATAGTTTGGTCCACCTCTTTACGAGCTTTACCAACCATTTCTTCAATACGAGCTGGATGGATACGACCATCTACAATCAATTTTTCCAGCGCAATACGAGCCACTTCACGACGAATTGGATCGAAGCCGGAAAGAATAACTGCTTCTGGCGTGTCATCGATAATCAAATCAATACCTGTTAATGTTTCGAGTGCACGAATGTTACGGCCCTCACGACCGATAATGCGACCCTTCATTTCATCATTAGGCAATGCCACTACGGATACGGTAGTTTCCGCTACATGGTCAGCTGCACAACGTTGGATAGCAGAGGAGATAATTTCTTTCGCTTTTTTCTCCGCTTCATCCTTAGCTTGCTGCTCCATTTCCTTAACCATAATCGCCGTTTCATGACGGATTTCTTGTTCCACATTCGTTAACAAGATATTTTTTGCTTCTTCAAACGTCATGCCAGAAATACGTTCTAATTCTGCCATTTGTTTTTCATACAAAGCTTCTACCTTTTCACGGCTTTGGGCTAAGTCAGCTTCTTTGCGATGTAAAGCTTCCTCTTTGTGCTCAATATTGTCTAATTTTTTATCCAAAGATTCTTCTTTTTGAAGAATACGACGTTCCATACGTTGAAGTTCAGAACGACGATCTTTATTTTCTCGTTCCACATCAGAACGGAGCTTATGAATTTCTTCTTTCGCTTCTAATAAAGCTTCTTTCTTTTTAGACTCAGCTGTGCGTTCACCATTTGCAATGATGCGTGCAGCCTCTTGTTCAGCTTGATTCAGTTTTCCTTCAGCAATATTTTTTCTTAAAAAATAGCCTACCCCTAGTCCAATCAGTACCATTACCACTGCAATTAGACTATACTCTAAAATTTCTTTCACCTCCTTCTATTTCTCAAAATTGAGCTTTCATGCTCCTTTTTATGCCCTTTATGCATTAAATTATCAATTAGCCATATCATCATATAAATAAATAAGGCTATTATTAATTTTAGACTTCAAAGCCCTTTCTGTCAAGATTTTACAAGCTTAGTAAGGCCTCTCAAAAAGCATAATTTATTCATAAAAATCATTGCATACAACTTGAATTGTGCTTGTTGAGAACCCCCTGTATTTGAGAAAACTGAAAACCTTTACCCGAGGAGTCTTTTCTTCATTGAGAATAGATCCAAACTTTTTCTCTACCACCCGATAAGCAGCTTTTACCTCATCATAAGCAGAAATTTCTTGAGGAATCGCAAGTCCTCGAAGTTTCATTTTTTGCTTAATCATATAAGCACCGTATTTTTGTTCTTTCATCAAATAGGTTAATACTTGCTCCGATAAACGTTCATCATTGATGTAATCATAATCTCTAAGGCGCTCAAGGACCCTCTCAATGATAGGGTCCTCGAATTGTTTACGTCTCATTTTTTGTGTCAGTTCATAAGAACTAAGAAAGCGTTGAGCTAAGAAGCGATACGCTTGATCCATAGCAGCTTGCATCGTTTCGTCACTCATGATTATACTTCTTCAGTTACTTCTTCACCGATTACATCGATTTCTTCAGTACCAACAGCTAATGTATCACGAATAATGCGATCGATTTCATCAGCTATTTGTGGATTGTCTAGCAAGTATTGTTTAGCCGCTTCTTTACCTTGGCCCATACGTTCCCCATTATAAGAATACCAAGCACCAGATTTATTAATAATTTCCATATTTGTACCAATATCAATAAGTGTGCCAGTTTTAGAAATACCTTCGCCATACATCAAATCAAATTCAGCGGTCTTAAATGGAGGTGCCACCTTATTTTTAACAACTTTGACTTTTGTGCGAGCACCAACATTTTCATTATTTGCTTTGATCAATTCCCCTTTACGAACATCAAGACGCACAGAAGAATAGAATTTCAACGCACGACCACCAGTTGTTGTTTCAGGATTACCAAACATAACACCTACTTTTTCACGCAATTGGTTGATGAAGATAACAACTGTTTTGGATTTACTGATGATACCAGTCAATTTACGCAAGGCTTTACTCATCAAACGAGCTTGTAAACCTACATGAGCGTCACCCATTTCACCATCAATTTCCGCTTTAGGTACCAATGCTGCTACGGAGTCAACTACAACAATATCTACTGCACCACTGCGAACAAGGGCTTCTGTAATTTCAAGAGCTTGTTCTCCATTATCTGGTTGAGAAATCAACAAATTATTGATATCTACACCCAAATTGCGAGCATATACAGGATCCATCGCATGCTCCGCATCAATAAATGCTGCAATGCCACCTTGTTTTTGAGCTTCTGCTACCGCGTGAAGAGCTACTGTTGTTTTACCAGAAGATTCTGGACCATAGATTTCAATTACACGACCACGAGGGAAACCACCTACACCAACAGCAATATCGATAGCTAGAGAACCAGAGGAAATCACCTCTACATTCATGCGATCTGCCGCCTCACCAAGACGCATAATAGCACCTTTACCAAAATCTTTTTCAATTTGTTTTAATGCGTTATCCAACGCTGCTTGTCTACCATCTACAGCCAT

Protein sequences of DBSCAN-SWA_5

>NZ_CP019721|1974848:1985379|1984338_1985379_-|WP_008601363.1|DBSCAN-SWA
MAVDGRQAALDNALKQIEKDFGKGAIMRLGEAADRMNVEVISSGSLAIDIAVGVGGFPRGRVIEIYGPESSGKTTVALHAVAEAQKQGGIAAFIDAEHAMDPVYARNLGVDINNLLISQPDNGEQALEITEALVRSGAVDIVVVDSVAALVPKAEIDGEMGDAHVGLQARLMSKALRKLTGIISKSKTVVIFINQLREKVGVMFGNPETTTGGRALKFYSSVRLDVRKGELIKANNENVGARTKVKVVKNKVAPPFKTAEFDLMYGEGISKTGTLIDIGTNMEIINKSGAWYSYNGERMGQGKEAAKQYLLDNPQIADEIDRIIRDTLAVGTEEIDVIGEEVTEEV
>NZ_CP019721|1974848:1985379|1975967_1976699_-|WP_077708558.1|DBSCAN-SWA
MEPRPMMDRLEAVFSIVPKAHAIADIGTDHGYLAVELINRQRAEYVIAGDVHKGPLESARSYVESCGLADKVDCRLGDGLKVTEKGELNGAICCGMGGFLMRDIVDAGPEPLEFYVLQPQNGQKELRQYMVQKGYVIVLEIIVEDAGKLYTAFLAVRNDCVEAYTGMTEYVDVYQSLPEDSLLWSVGALLEQDRPPLWMKYIEYLIYQRQCALDDMTEKLNHTDKYQDLEQEVNFLRNLLENK
>NZ_CP019721|1974848:1985379|1977031_1977595_-|WP_021148327.1|DBSCAN-SWA
MDTKKIESLIYQLLEALGEDPNRDGLLETPKRVAQMMEEVYEGIQYTNAEIAEMYGKTFAVDTNQMVVVKDITCFSHCEHHMALMYDMSISIGYIPKGRVIGLSKIPRIAEMCCKRLQLQEKIGEDIAEVISLATGSNDVIVHIISSHSCMSARGIKSTDSQTTTLTTKGVFNEDHMIHRFMLMKQS
>NZ_CP019721|1974848:1985379|1982173_1983679_-|WP_038125528.1|DBSCAN-SWA
MVLIGLGVGYFLRKNIAEGKLNQAEQEAARIIANGERTAESKKKEALLEAKEEIHKLRSDVERENKDRRSELQRMERRILQKEESLDKKLDNIEHKEEALHRKEADLAQSREKVEALYEKQMAELERISGMTFEEAKNILLTNVEQEIRHETAIMVKEMEQQAKDEAEKKAKEIISSAIQRCAADHVAETTVSVVALPNDEMKGRIIGREGRNIRALETLTGIDLIIDDTPEAVILSGFDPIRREVARIALEKLIVDGRIHPARIEEMVGKARKEVDQTIKEAGEQATFEADVHGLHPEIVKILGRLKYRTSYGQNVLKHSIEVSHLAGLMAAELGCDVTLAKRGGLIHDIGKALDRELEGSHVQIGVDVARKYRESAAVINCIGAHHGDEEFQTVEAVLVAAADAISAARPGARRETLENYLKRLSKLEEIAESFEGVEKCFAIQAGREIRVVVKPDKIDEAESTLLVRNIVKRIESELEYPGQIKVVIIRETRVVDYAK
>NZ_CP019721|1974848:1985379|1974848_1975952_-|WP_077708557.1|DBSCAN-SWA
MITVQQVITLMEQLAPRSYAESWDNVGLMVGDRNVVVTGVVTTLDVTEETVEYAIEQNCNLIVSHHPLIFKGLKQISCDTAHGRTINKLIQHKIAVYSAHTNLDIAPGGLNDMLAKQLGLIDIKGFIKTGEEALYKVTTFVPESSADAVRLAMGDAGAGRIGNYEHCSFSIHGEGRFVGNEDSHPVIGAAGALTVVPEVQVNAIVDGTHLSKVVAAMKAAHPYEEVAYEVLNIVEPTSSTQYLGRVGRLPNALNLDSFREWVQEALPDANIRFAGIVPKAIQSIALCSGAGAEFIKDAARLHVDAYITGDVKYHEAQMAKELGLLVVDAGHFGTESIVAHGLRDYLISAGLAVPVKAFTEQNDFFFV
>NZ_CP019721|1974848:1985379|1978411_1978750_-|WP_021148329.1|DBSCAN-SWA
MFTVTKRLEVSASHQLKLDYPSKCQNLHGHNWIITVHARSEELDHNGMVIDFTIIKEKIHGRLDHRHINDVLGDINPTAENMAKWIADELGPKCFKVEVQESEGNTAVYERD
>NZ_CP019721|1974848:1985379|1978955_1980116_-|WP_077708559.1|DBSCAN-SWA
MAKKVQKSQIEEIVEQLLEKGRKSGVLTQSEISDALHEQTEITAEQLDDIYTTLGKLNVEIVADIDADDTDNHTIETDEDEDEVSSEKKIAIDLSVDSGVNIDDPVRMYLKEIGRVPLLSADEEIVLAKQIEAGAQEDATYKDIQLSKKAKKKLVDANLRLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVDKFDYTKGYKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINKLIRISRQLLQDKGREPLPEEIAEGMGITVERVREIQKIAQEPVSLETPIGEEEDSHLGDFIEDQDAIAPDDAASYILLQEQIEDVFTCLTDREQQVLILRFGLKDGKPRTLEEVGQHFNVTRERIRQIEGKALTKLRNRGKRDKIKDFL
>NZ_CP019721|1974848:1985379|1983892_1984336_-|WP_039965037.1|DBSCAN-SWA
MSDETMQAAMDQAYRFLAQRFLSSYELTQKMRRKQFEDPIIERVLERLRDYDYINDERLSEQVLTYLMKEQKYGAYMIKQKMKLRGLAIPQEISAYDEVKAAYRVVEKKFGSILNEEKTPRVKVFSFLKYRGFSTSTIQVVCNDFYE
>NZ_CP019721|1974848:1985379|1980144_1981917_-|WP_077708560.1|DBSCAN-SWA
MSRYFENELIEQIKDANDIVSVVSEHVALKKRGKNYWGCCPFHNEKTPSFSVAPEKGFYYCFGCHASGNAIKFLMELEHLTFVEALERLANRANIPLPEAKLSPEQRARDERRKKLYEASDLATTFFHNCLTQTSIGKVGLDYLKKRGLTQETIEQFKLGFAPDGWDKLYRAFHDRGIDDSILLELNLVRKNQKGQFYDFFRNRIMFPIMDGKGRVVAFGGRVMDDSTPKYLNSPESSIFEKGKLLFAFDKAYKSIREEKQAILVEGYMDVISAHNHGVTNVVASLGTAYTRDHGHILMRQAEEIVLAYDMDGAGRQAAARAIELLQNTDFKVRVLAMPDGKDPDDYVRNHGGQAFKELVAKAVKPLDYLLSESLIKHDTNDTEGKQAVMADVFPYIANIDSQTQRDDALKTLALPLWLDNSTIFRYFRDYVKKGQIELVDTASTPLPTQDLPRGDAEKLLSLAFTNGEVLQHMMSYLPLEDFEKIEYRGIIEKLFTLYKSEGRLDETAIQSVLSSQEYDIYSRLVVMSDDEYKVQVPALIRKIRLHSLREQYKAHSIMADQLKRAGDSTFISELHKCQEIQNLIREWSK
>NZ_CP019721|1974848:1985379|1977681_1978425_-|WP_042986446.1|DBSCAN-SWA
MNVIEIFASIDGEGSRQGLLTTFLRLHDCNIRCSYCDTTYSYGIDSIFTEMTVAEVADVIESLGNHRITITGGEPLLQEAAVVELIDELNRRKAETMQDNTSGQAGSTCIIDIDKFDKREMLNNSLYDFNIETNGTIIPSFHRDNVWFTYDYKTPSSLAEESMNIDIFKVATERDLIKFVVGSPEDLDCMRRIIDQYPTAAQIYVSPVWGQIEAVLIIDYMKAYNLQNVRFQLQIHKFVWDPDTKGV

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_077708557.1|1974848_1975952_-	Nif3-like dinuclear metal center hexameric protein	A0A2P1EK93	Megavirus	6.4e-14	38.0
WP_077708558.1|1975967_1976699_-	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_021148327.1|1977031_1977595_-	GTP cyclohydrolase I	S4U0J3	uncultured_phage	7.1e-62	67.2
WP_042986446.1|1977681_1978425_-	4Fe-4S cluster-binding domain-containing protein	S4TZT1	uncultured_phage	4.7e-53	47.8
WP_021148329.1|1978411_1978750_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	4.4e-43	68.8
WP_077708559.1|1978955_1980116_-	RNA polymerase sigma factor RpoD	F4YCU2	Synechococcus_phage	9.3e-40	37.6
WP_077708560.1|1980144_1981917_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	1.8e-55	36.0
WP_038125528.1|1982173_1983679_-	ribonuclease Y	NA	NA	NA	NA
WP_039965037.1|1983892_1984336_-	regulatory protein RecX	NA	NA	NA	NA
WP_008601363.1|1984338_1985379_-	recombinase RecA	A0A0S2MVG1	Bacillus_phage	9.6e-121	63.6

Sequences of DBSCAN-SWA_6

Nucleotide sequences of DBSCAN-SWA_6

>NZ_CP019721|2043625:2053096|DBSCAN-SWA
ATTATAAGGTTTCAAGGAACGCTTCACGTTCCAATAACGCTTGTTGTTTTTGTTTATATTCTTCTAACTTTTCTTTTTCTTTTGCTACTACAGCTTCAGGAGCTTTTGCTAAGAAGCCTTGGTTAGACAATTTACCTTCCAAACGAGAAATTTCTTTTTCCATTTGGATTTTTTCCTTTGCAATACGCTCTCTTTCTTTTTCACCGTCAATCAAGTCTTTAAGTAAGAGATATACTTCCATACCATTGACAACGGTTACAGTCGCATTTTCTGGTTTTGGATCATCGGTACTAAGAATTGTTACTTTCTCAGCCCAAGCCAATGTTACGAAGTAGTCACTATGTTCTGCTACAGTTTTAGCTAATGCTTCATCTGTTGGCGCTACGATAACCTCAGCTTTTTTACCTAAAGGCACATTCATTTCAGCACGCATGTTACGAATACCTTTGATAGCATCCATCATAACTTCCATTTGACGTGCTGCCCCTTCAAGATTATCGAATTTCAATGCTTCAGGCCATTTAGTAACAACGATGCTGTCCCCTTCATGTGGCAAATGTTGCCAAATATGTTCAGTTACGAACGGCATGAATGGATGTAATAATTCGAGCATATGACGTAAGATTGTTACAAGTAAATATTGAACTGTATGACGATCACGTTCGTCGCTTTCACTATACAAACGAGGTTTCGCTAATTCAATGTACCAATCGCAGTACGTATTCCAAATGAAATCATATACGGAACTTGCAGCTTCACCAAGTTCGAATTTATCGAGATTAGATGTTACGCTTTGTACTGTTTCATTGTATTTCTGAACAATCCATTGGTCTGCTAATGTCAAATCATCTGCTGTTGGAACGAAACTTTCATCATAATTTGTAAGGTTCATCAATACAAATTTTGATGCATTCCAAATCTTATTGGCGAAGTTACGGTTAGCCTCAACACGTTCCATGTAGAAACGCATATCGTTACCAGGTGTATTGCCTGTTACAAGGGTAAAACGTAATGCATCAGCACCATATTGATCAATTACATCAAGAGGATTGATACCATTACCCAAGGATTTACTCATTTTACGGCCCTGGCTGTCGCGAACAAGGCCATGAATAAATACATGTTTAAATGGAATTTCATGTTCAAACTCTAGAGCCATAAAGATCATACGAGCAACCCAAAAGAAGATGATATCGTAACCAGTTACAAGCACACTTGTTGGATACCATTGTTTAAGTTCTGGAGTTTGCTTAGGCCAACCCATTGTGGCAAACGGCCATAAACCAGAGCTAAACCATGTATCAAGAACATCTGGATCTTGTGTAACATGACCGTGGCAATGAGGACATTCTGTAATATCTTCACGGCTAACGATAGTTTCACCACAGTCATCACAATACCATGCAGGAATGCGATGGCCCCACCACAATTGACGAGAAATCGTCCAATCGCGGATATTTTCAAGCCAGTTCACATATGTTTTTGTAAAACGTTCAGGAACGAACTCTACTTCGTGGTCTTTAACAACCTTAAGAGCTGGCTCTGCCAATGGTTTCATATCTACGAACCATTGTTTAGATACCATTGGTTCGATGATTGTATTACAACGGGAGCAATGACCTACTGCATGGTCATGATCATCAATTTTTTCAAGTAGGCCTAATTCTTTGAGTTCTGCTACTACTTGTTTACGCGCTTCTTCACGAGGTAAGCCATTAAATTTGCCAGCACCTTCATTCATTGTTGCATCATTGTTCATAACAACGATGGATTCCAAATTATGACGTTGGCCCATTTCAAAGTCATTAGGGTCATGAGCAGGTGTAATTTTTACACAGCCTGTACCGAAGCTAGCATCTACATAGTCATCGGCAATTACAGGAATTTCTCGATTAACAAATGGCAAGATCAATGTTTTACCAATGAGATCTTTATAACGATCATCATCAGGATTTACTGCTACTGCTACGTCACCAAACATTGTTTCTGGACGAGTTGTAGCAACAACAACAAAACGATTATCATCACCTTTTACAGGATATTTAATATGCCATAAATGGCCATGTTCGTCTTCATGCTCAACTTCAACATCAGATAACGCAGTGGCACAACGAGGACACCAGTTGATGATGCGTTCACCGCGATAGATCAAACCTTTTTCATAAAGGCTTACAAATACTTCGCGCACTGCATGGTAATACCCTTCATCCAAAGTAAATCGCTCACGGTTCCAATCACAGGATGCGCCAAGGCTACGGATTTGTTTTACAATAGTATCACCATATTCTTTTTTCCATTCCCACACGCGCTCTACGAATTTTTCACGGCCCAAATCATAGCGAGATTTTCCTTCTTCTTTAGCAAGCATCTCTTCTACTTTGATTTGTGTAGCAATACCAGCGTGGTCTGTACCTGGCATCCACAATACATTGTAGCCTTGCATGCGTTTGAAACGGATGAGGATGTCTTGTAATGTGTTATCAAGGGCATGCCCCATATGCAACATACCAGTTACATTAGGAGGTGGTAATACGATACTAAATGGCTCTTTATTCGTGTCTACTTCTTCGTGAAAGTATCCTTGATTTTCCCAATAAGAATACCATTTGCCTTCTATTTCACCAGGATTATATGTGGTTAAATTTTCGTAGGTTTTCATCGTTCCTCCTAAAAGACTCCTTAGCGCTTCATAATTTTAGCCAATACAAATAGGCTTGTTTCATATAGCAATATCATAGGTAATGCAATCATCGTTTGCGAGAACATATCCGGTGTAGGTGAAATGACAGCACCTATGATAAAGGATATAAGAATAAATATCTTTCGCTTCGTTTTTAAAAAGCGTGATGTAATTAAGTTGAAATATCCCAAAATAATTAAGATCAACGGCAACTCAAAGATAAATCCAAAGGGCAGTACAAAGGATAATACAAAGTCCATATACTGACCAATAGAAAACATCGGCTGTAATTCATCTGTAGCAAAGCCCATAAAGAACTTCACTGCTGCAGGCAATACGAGAAAATAAGAAAATACAATACCTATCCCGAATAGACCAATTGCTACTGGTAAGATCCAGTTAGATAGCTGCTTTTCTCGCACAGTTAGTGCAGGCTTAACAAATAGCCAAATCTGATGCAATATAATGGGAGCGGCTATGACTAAGCCACCTACAACAGACACCTTCATATATGTAAAAAATGCTTCAGTAGGTCTCATATAATAGAGCTTGCCAGCCGGTTTTAGGAGTATTTCCAATAATAAGTCTACATAATAATAAGAAATACAAGTTCCCACAATAACCGCTACAGCTATTATAATCAATCGTTTTCGCAGCTCTGAAAGATGTCCTACAAGGGACAATTCCCTTGCTTCATCCATCATCTTCTGCTCTATAGCCGTATAAACTGGTTCATCTTCCACATCCTCAGAAATGTGTTGAGTTGCCACCTTATATCGTTCTTGCTCAGACTTTTGTTCTGCTTCACGCCTTTTTTGACGAACTACACTATCAAAAGAAGGTTTTTGCATGGGATATTCGAAATCCGATTTTGGTTCGAATGGTTCCATATTATACCTTTCTATCAGCCAGATTTTCTACAGCCATCACAAGAAATTCCTTCCCTGGGAAATCACGCACTGCAGCGAGTGCCGCTAGAGCATCTTTACAATATTTATCAGCTACAGCTAATGTATTATCAATTCCACCTTGAGCAATAACATAATCAATAATGTCTTGCTCATTACCACCATTATTTAAGCCTTTAATCTCTTCAAGCAATTTATCTTTATTACCATCGTTAACGATGCTTAATAACGGATACGTCAATAGTCCCTCTCGAAGATCATTCCCTACAGGCTTTCCCGTTGTTTCCGCTGTTTCACGATAATCCATAATATCGTCTGTAATTTGGAATGCCATGCCTAATGCATGACCATATTTTTTCAACTCTATGATTTCATCCTCTTGCCAATCTCCTAAGAGACCACCAAGCTCCATACAGCCTTCCATGAAGTCTGCTGTTTTCTTTTGCGTCTTTGTCATATAACGCTCTATGCCTTGATCGATGCGATATACATCTTCCATTTGCATGAACTCACCTTCTACGAGGCATGTAATAATATGAGAGAATACTTGAAGATACTTCATATTCGTCATTTCAGATACGATTTTAAATGCTTTAGCAAATAAATAATCACCACTAAGGATAGCTACCTTATTGCCTTTATGCATGTGAATTGTATCCTCCCCACGGCGAATTTCAGCTTGATCTAAAACATCGTCATGGATAAGTGTTGCTAAATGAAGCATTTCAACAGCCTCAGCAATTTTAATGCGTTGACGCTCTATAGATGTACCTGCATTAGCAATCAATAGACACAATTGAGCGCGCAAACGCTTACCACCTGCTGCTGATAACGGTCGAATCAGTGCATTGAAGTCCTCTGCACCGGTATTAAAAGATGATGCAAGAGACTCTTCGACACGCTCTAAATCTAGAGCAATGCGTTCCATAATCTCTAATTCGTTCGTTTGACTCATGCTTCATCTCCTACCAAAATTTTATTGATTCGTTGTTGTAAAAGCTCACGTCCAGTATGCTTTAAAGAGCTGTACAAAATCGGCGGGGTAGCCGTTGGATATAGCTCTTTAATAATAGACAAGTTTGCAGACTTTTCTTTAGCCGTCAATTTATCGGCCTTGGTCACTACAATTTGTAACGGAACACCGGCTTCGACGAGCCAATCAAAGGCCACCTTATCAATGGCCATTTCAGGATGGCGACCATCGATAAGTAAACACAACAACATCAATCGTTCAGAATGTAAAATATAATCGGCAATAAAGGAAGACCACAGATTGCGGTTTCCTTTATTTGTCTTTGCAAAACCATAACCAGGAAGGTCCACGAGAAACCAGTTATATCTGCGTTCCTCGGTGTCAGAAATATCCTCTTTTGATTCAATATCAAAGTAGTTTATCGTCTTAGTCTTACCTGGCTGACCACTAACGAGGGCTAACCCACGATAGTTACATAAAGAATTAATCAACGAAGACTTGCCCACATTAGAGCGTCCAAGGAAGGCGATTTCTACGGTATCCCCTTCAGGATATTGATCCGCCTTCACACAGGAAGTATTATATTTTGCAGCTATAATACGAGGCCCCTTTGGTTCTTTTCGTGTATATTGTGGTTTTGGGCCCATTGGTTTAGTGGATTTTTTCTTCTTTTGCATTACACAAGTGCCTTTGCTAATACTTCATCCATTGTCTTAACTGGCGTAATGATGAGTCCTTCTTTCACAATGTCAGGTAATTCTGCAATATCCTTTTCATTGCCTTTTGGAATCAACACCTCTTTAATACCATGAGACAAGGCTGCTAATAATTTTTCTTTTAAGCCGCCTATTGGTAATACGCGGCCACGCAATGTGATTTCACCAGTCATGGCAATATCAGAACGAACCTTGCGGTTAGTCAAAATAGATACCATAGCTAATGTCATTGTAATACCTGCTGAAGGACCATCTTTAGGGGTTGCCCCTTCTGGCAAGTGAACGTGAATATCAAGCTTTTTATAAAAATCTTCTTCAATCTTTAAAGCTTTTGCATTATGGCGAATATAACTCATAGCCGCTTGACCAGACTCTTGCATAACCTTGCCGAGACTACCAGTTAAAGCCAATTTACCGGTACCATTCATAGTTGTAGCTTCACATGGTAATACTACACCACCAACAGATGTCCAAGCTAATCCATTTACATAGCCAACTTGTGCTTTCTTTTCTCGCTCTTGGTCAACAAAGATTGGTGCGCCTAAGAATTCGTGAAGATTCTTAGTAGTGACTTTTGGTGCGTCTCCGCCTTCTTCAACTACTTTGAAAGCAATCTTACGGCAAATCTTAGCAATTGTTTTCTCTAAAGTACGAACACCTGCTTCGCGAGTATATTCGGAAATTACCTTTCTTAACACAGCATCAGATAATTTAACCTTGTAATCTTCAAGGCCATTTTTCTTAATTTGCTTAGGTGTTAAGTAACGCTTAGCAATTTCTAGTTTTTCTTCTTCCATATAGCTGGACAACTCAATAATTTCCATACGATCTAACAATGGACCAGGAATATTAGATGCTACATTAGCCGTAGTAATCCAGAAAACTTCAGAGAAGTCGAACGGTACTTCGATAAAGTGATCACTAAATGTGCTATTTTGTTCTGGATCCAATACTTCTAATAACGCTGAAGATGGATCACCTTTATAATCAGATGCTAATTTATCAATTTCATCCAATAAAAATACAGGATTCTTAGTACCTACATTTTTTAACCCCTGAATCATACGACCAGGTAAAGCACCAATATAAGTACGTCGATGTCCACGAATTTCAGCTTCATCACGAACACCACCTAAGGATGCACGGATAAACTTACGATTCATTGCTTTAGCAATAGAGGTAGCCAAAGAGGTTTTACCAACGCCTGGTGGGCCTACTAAACAAAGAATAGAGCCACTATTTTTACCAGTTAATTTACGAACCGCTAAAAATTCTAAAATGCGTTTCTTAACCTTTTCAAGGCCATAATGATCGGCCTCGAGCATAGCATGAGCGCCCTTAATATCTAAACGGTCTTCCGTTAATTCGTTCCACGGTAATGCCAATACCCAATCTAGGTAATTGCGCAAAATTGTTGCTTCCGGCATCAATTGAGGCATGCGGCTGTAACGAGAAATTTCTTTATCAATACGCGTATGTACGTCTTCACTTAGATTAAGTGCTTTTAACTTAACTCGTAGTTCTTCTGCCTCCTCCTCGGGATCCCCTTTATCACCCAACTCATCGTGGATAACGCGGATTTTTTCGCGCAAGAAATATTCCTTCTGCGCTTTTTCCATAGATTGACGCACTTGATTATTGATGGAATTTTCCAAATCAGAGATTTGTAATTCCATATTTAAAATGCCTACAATCATGTTAAGACGACGAGCCACAGATAATTCTTCAAGTAACTCTTGACGTTTCAAATTATTAATAGGCAATAGAAATGCAACTTGGTCAGCTAATTCACAAGGATTGCGTAATTCCATAACGCGCGTTACACCTTCATCAGTAACTGATTTAGCTTCTTCTGCCCATTCGCCAAATTTAGCTTGAACCAAACGACGATAAGCTTCAAGCTCTACATCGTCTTCAAATTCAGACGCCACTCGTTCATAGTCTCCTATATAATAAGGGTCCATGCTAGTAATATTCATAAGACGAATACGAGTGATGCCCTCTACAAGAACACGTACTATACCACCTGGTAAGCGCAACATTTGTTTAATTTTTACTAATGTACCCATTTGGGCTAAATCATGAACTGTTGGCGCATCTACAGCATCATCTTTTTGAGTTACGACAGCTAAAATGCGGTCCTCATTCATTGCGGCTTCCACCGCCTTAATGGATTTGTCTCGACCGATATCGAGGTGAATCACGATATTCGGGTATACTACCATGCCTCTGAGAGGTACGGTAGGGATCCCAACTTCGAGTAAATTCATACTTCCTCCAGGTATATATATTATGAAAAGAAACTCATTCCTACACAGAAATGAGTTTCTTCGAATTACGATTTCAACTGGATGTCTTGGTCTGCCTCATTTTTGAGTATAGGTTCACCTGTGCTTAATACGGATTCACGATTCACAATGCACTTAGTTACTTCCGGCATGGAAGGAACCTCAAACATTACGCGTTTCATCACCTTTTCAATGATAGCACGCAAACCACGAGCACCTGTTTTTCGCTGTAATGCTTCATCAGCGATTTCTTCTAATGCATCTTCAGTGAAAGTTAATTCTACACCATCAAGGGATAGAATTTTTTCATATTGTTTTGTTAATGCATTTTTAGGCTTTGTCAAAATTTGAATTAACGCATCTCTGTCTAATTGATCTAATGTCACCATTACTGGCAAACGTCCAATAAACTCAGGAATCAAGCCAAATTTTAATAAATCTTCAGGTACAACATCTTTTAAGATAGCCGATACATTGCGTTCTTCTTTACGCTGTACATCTGCACCAAAGCCAAGTGTTTTCTTAGCGGTACGCTTAGTAATAACCTTATCCATACCATCAAATGCACCACCACAAATAAAGAGAATATTCGTAGTGTCAATTTGAAGCATTTCTTGATTAGGATGCTTCCTACCACCTTGTGGGGGAACAGAAGCGACAGTACCTTCTAAGATTTTAAGCAATGCTTGTTGTACGCCTTCACCAGACACATCACGTGTAATGGAAGGGTTCTCAGACTTACGAGCAATCTTATCAATTTCATCGATATAGATAATGCCACGTTCAGCCCGAGCTATATCATAATCTGCAGCTTGGATAATTTTGAGTAAGATGTTTTCTACATCTTCCCCTACATACCCAGCCTCAGTTAAGCTTGTAGCATCTGCAATAGCAAATGGTACTTCTAGCATTTTCGCTAAGGTTTGAGCCAATAGTGTTTTACCACTACCAGTAGGACCAATGAATAAAACATTAGCCTTTTGTAATTCTACATCATCAACTACATTATCTGTTTGTAAACGTTTGTAGTGATTATATACAGCCACGGCTAAAGAGATTTTAGCATCATCTTGACCAATGACATATTCGTCAAGATGAGCTTTAATTTCTCTAGGCGTTGGCAATTCTTTTAAATTGAAGTCGTCCGTCTCAACCGCACCCAACTCATCTGCAATGATGCGTTCACAAACTTCAACGCATTCATCACAAATATACACGTTAGGCCCCGCCACTAATTTGCGGACTTCTTCGCTTGTGCGTCCACAAAAACTGCAGCGCATAGTGTCTTTATCTTTTGCCAAGGGGCGCCTCCATTACTTGCTTTCTACAGGTTCTCTTGTGAGCACCTCATCAATTAAGCCGTATTCAACGGCATCCTGAGCACTCATGAAGTTATCGCGATCTGTATCGCGAGCTACTACTTCAATATCTTGTCCACTGCGAGAAGCTAAGATACCATTTAACTCTTCACGCATGCGAAGAATCTCACGGGCATGGATTTCAATTTCAGATGCTTGTCCTTGTACACCACCTAATGGTTGGTGAATCATGATGCGCGCATGAGGTAACGCATATCGTTTACCTTTAGTGCCAGCTGTTAAAAGCACAGCACCCATGCTCGCTGCAGAGCCTACACAAATAGTAGACACATCTGGTTTAATATATTGCATCGTATCATAAATAGCCATACCTGCGGTTACAACACCACCAGGGCTATTGATGTACAAATGGATATCCTTATCAGGATCCTCTGCTTCCAGGAATAACATTTGCGCAATAACCGCATTTGCCACATTATCATCGATGGGGCCACCAAGGAAAATAATGCGATCCTTTAACAAGCGAGAGTAAATATCATAGGAACGCTCTCCGCGTTCACCTTGTTCAACTACGATTGGTACATACAT

Protein sequences of DBSCAN-SWA_6

>NZ_CP019721|2043625:2053096|2048861_2051171_-|WP_004696511.1|DBSCAN-SWA
MNLLEVGIPTVPLRGMVVYPNIVIHLDIGRDKSIKAVEAAMNEDRILAVVTQKDDAVDAPTVHDLAQMGTLVKIKQMLRLPGGIVRVLVEGITRIRLMNITSMDPYYIGDYERVASEFEDDVELEAYRRLVQAKFGEWAEEAKSVTDEGVTRVMELRNPCELADQVAFLLPINNLKRQELLEELSVARRLNMIVGILNMELQISDLENSINNQVRQSMEKAQKEYFLREKIRVIHDELGDKGDPEEEAEELRVKLKALNLSEDVHTRIDKEISRYSRMPQLMPEATILRNYLDWVLALPWNELTEDRLDIKGAHAMLEADHYGLEKVKKRILEFLAVRKLTGKNSGSILCLVGPPGVGKTSLATSIAKAMNRKFIRASLGGVRDEAEIRGHRRTYIGALPGRMIQGLKNVGTKNPVFLLDEIDKLASDYKGDPSSALLEVLDPEQNSTFSDHFIEVPFDFSEVFWITTANVASNIPGPLLDRMEIIELSSYMEEEKLEIAKRYLTPKQIKKNGLEDYKVKLSDAVLRKVISEYTREAGVRTLEKTIAKICRKIAFKVVEEGGDAPKVTTKNLHEFLGAPIFVDQEREKKAQVGYVNGLAWTSVGGVVLPCEATTMNGTGKLALTGSLGKVMQESGQAAMSYIRHNAKALKIEEDFYKKLDIHVHLPEGATPKDGPSAGITMTLAMVSILTNRKVRSDIAMTGEITLRGRVLPIGGLKEKLLAALSHGIKEVLIPKGNEKDIAELPDIVKEGLIITPVKTMDEVLAKALV
>NZ_CP019721|2043625:2053096|2052502_2053096_-|WP_004696517.1|DBSCAN-SWA
MYVPIVVEQGERGERSYDIYSRLLKDRIIFLGGPIDDNVANAVIAQMLFLEAEDPDKDIHLYINSPGGVVTAGMAIYDTMQYIKPDVSTICVGSAASMGAVLLTAGTKGKRYALPHARIMIHQPLGGVQGQASEIEIHAREILRMREELNGILASRSGQDIEVVARDTDRDNFMSAQDAVEYGLIDEVLTREPVESK
>NZ_CP019721|2043625:2053096|2051236_2052469_-|WP_038125529.1|protease|DBSCAN-SWA
MRCSFCGRTSEEVRKLVAGPNVYICDECVEVCERIIADELGAVETDDFNLKELPTPREIKAHLDEYVIGQDDAKISLAVAVYNHYKRLQTDNVVDDVELQKANVLFIGPTGSGKTLLAQTLAKMLEVPFAIADATSLTEAGYVGEDVENILLKIIQAADYDIARAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPNQEMLQIDTTNILFICGGAFDGMDKVITKRTAKKTLGFGADVQRKEERNVSAILKDVVPEDLLKFGLIPEFIGRLPVMVTLDQLDRDALIQILTKPKNALTKQYEKILSLDGVELTFTEDALEEIADEALQRKTGARGLRAIIEKVMKRVMFEVPSMPEVTKCIVNRESVLSTGEPILKNEADQDIQLKS
>NZ_CP019721|2043625:2053096|2047195_2048167_-|WP_021148372.1|DBSCAN-SWA
MSQTNELEIMERIALDLERVEESLASSFNTGAEDFNALIRPLSAAGGKRLRAQLCLLIANAGTSIERQRIKIAEAVEMLHLATLIHDDVLDQAEIRRGEDTIHMHKGNKVAILSGDYLFAKAFKIVSEMTNMKYLQVFSHIITCLVEGEFMQMEDVYRIDQGIERYMTKTQKKTADFMEGCMELGGLLGDWQEDEIIELKKYGHALGMAFQITDDIMDYRETAETTGKPVGNDLREGLLTYPLLSIVNDGNKDKLLEEIKGLNNGGNEQDIIDYVIAQGGIDNTLAVADKYCKDALAALAAVRDFPGKEFLVMAVENLADRKV
>NZ_CP019721|2043625:2053096|2048163_2048862_-|WP_008601447.1|DBSCAN-SWA
MQKKKKSTKPMGPKPQYTRKEPKGPRIIAAKYNTSCVKADQYPEGDTVEIAFLGRSNVGKSSLINSLCNYRGLALVSGQPGKTKTINYFDIESKEDISDTEERRYNWFLVDLPGYGFAKTNKGNRNLWSSFIADYILHSERLMLLCLLIDGRHPEMAIDKVAFDWLVEAGVPLQIVVTKADKLTAKEKSANLSIIKELYPTATPPILYSSLKHTGRELLQQRINKILVGDEA
>NZ_CP019721|2043625:2053096|2046303_2047194_-|WP_021148371.1|DBSCAN-SWA
MEPFEPKSDFEYPMQKPSFDSVVRQKRREAEQKSEQERYKVATQHISEDVEDEPVYTAIEQKMMDEARELSLVGHLSELRKRLIIIAVAVIVGTCISYYYVDLLLEILLKPAGKLYYMRPTEAFFTYMKVSVVGGLVIAAPIILHQIWLFVKPALTVREKQLSNWILPVAIGLFGIGIVFSYFLVLPAAVKFFMGFATDELQPMFSIGQYMDFVLSFVLPFGFIFELPLILIILGYFNLITSRFLKTKRKIFILISFIIGAVISPTPDMFSQTMIALPMILLYETSLFVLAKIMKR
>NZ_CP019721|2043625:2053096|2043625_2046283_-|WP_077708585.1|tRNA|DBSCAN-SWA
MKTYENLTTYNPGEIEGKWYSYWENQGYFHEEVDTNKEPFSIVLPPPNVTGMLHMGHALDNTLQDILIRFKRMQGYNVLWMPGTDHAGIATQIKVEEMLAKEEGKSRYDLGREKFVERVWEWKKEYGDTIVKQIRSLGASCDWNRERFTLDEGYYHAVREVFVSLYEKGLIYRGERIINWCPRCATALSDVEVEHEDEHGHLWHIKYPVKGDDNRFVVVATTRPETMFGDVAVAVNPDDDRYKDLIGKTLILPFVNREIPVIADDYVDASFGTGCVKITPAHDPNDFEMGQRHNLESIVVMNNDATMNEGAGKFNGLPREEARKQVVAELKELGLLEKIDDHDHAVGHCSRCNTIIEPMVSKQWFVDMKPLAEPALKVVKDHEVEFVPERFTKTYVNWLENIRDWTISRQLWWGHRIPAWYCDDCGETIVSREDITECPHCHGHVTQDPDVLDTWFSSGLWPFATMGWPKQTPELKQWYPTSVLVTGYDIIFFWVARMIFMALEFEHEIPFKHVFIHGLVRDSQGRKMSKSLGNGINPLDVIDQYGADALRFTLVTGNTPGNDMRFYMERVEANRNFANKIWNASKFVLMNLTNYDESFVPTADDLTLADQWIVQKYNETVQSVTSNLDKFELGEAASSVYDFIWNTYCDWYIELAKPRLYSESDERDRHTVQYLLVTILRHMLELLHPFMPFVTEHIWQHLPHEGDSIVVTKWPEALKFDNLEGAARQMEVMMDAIKGIRNMRAEMNVPLGKKAEVIVAPTDEALAKTVAEHSDYFVTLAWAEKVTILSTDDPKPENATVTVVNGMEVYLLLKDLIDGEKERERIAKEKIQMEKEISRLEGKLSNQGFLAKAPEAVVAKEKEKLEEYKQKQQALLEREAFLETL

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_077708585.1|2043625_2046283_-|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	3.4e-170	41.7
WP_021148371.1|2046303_2047194_-	twin-arginine translocase subunit TatC	A0A1B1IVR7	uncultured_Mediterranean_phage	4.0e-19	28.9
WP_021148372.1|2047195_2048167_-	polyprenyl synthetase family protein	A0A1V0SE37	Indivirus	8.6e-07	23.8
WP_008601447.1|2048163_2048862_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_004696511.1|2048861_2051171_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	1.5e-177	44.7
WP_038125529.1|2051236_2052469_-|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	9.9e-141	62.7
WP_004696517.1|2052502_2053096_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	4.0e-55	55.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage
NZ_CP019721.1|WP_077708127.1|1068129_1068390_+|hypothetical-protein	1068129_1068390_+	86 aa aa	NA	NA	NA	1063084-1139493	yes
NZ_CP019721.1|WP_077708128.1|1068376_1068949_-|hypothetical-protein	1068376_1068949_-	190 aa aa	NA	NA	NA	1063084-1139493	yes

Protein sequences of NZ_CP019721.1|WP_077708127.1|1068129_1068390_+|hypothetical-protein

>NZ_CP019721.1|WP_077708127.1|1068129_1068390_+|hypothetical-protein
MKSPLQRHMDNLGNKTEEGGETSITKKEPHDEAQKKWIIFRYFNALKYNKDQSLEEKLQDIRYCTRVNLGLFVIAVILTILNITRI

Self-targetings in the prophage

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP019721_3	TypeIII	3.4|531672|41|NZ_CP019721|CRT	531672-531712	41	1072160-1072200	0

1. spacer 3.4|531672|41|NZ_CP019721|CRT matches to NZ_CP019721 position: 1072160-1072200, mismatch: 0

taatcaagcacgtaattacgtaccaaacctaacgtaattat	CRISPR spacer
taatcaagcacgtaattacgtaccaaacctaacgtaattat	Protospacer
*****************************************

Protein sequences of NZ_CP019721.1|WP_077708128.1|1068376_1068949_-|hypothetical-protein

>NZ_CP019721.1|WP_077708128.1|1068376_1068949_-|hypothetical-protein
MKALPISNLQLSQNSIEQEYLNYKEELDSFDSHAHSLTNENLEKLILFINRKSKTYAELKAEVSILNDATLQLYLSNTPKKKVEPPFYSIERISAISNTTSLIHSYFKLVTIPKDFFAPYYFDDSDEFQLTVSGLNFLHQLEKENHTLQLAEESLRISKESAKYGKFAAWLAGIGIFTTIIIAILTFIFS

Self-targetings in the prophage

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP019721_3	TypeIII	3.4|531672|41|NZ_CP019721|CRT	531672-531712	41	1072160-1072200	0

1. spacer 3.4|531672|41|NZ_CP019721|CRT matches to NZ_CP019721 position: 1072160-1072200, mismatch: 0

taatcaagcacgtaattacgtaccaaacctaacgtaattat	CRISPR spacer
taatcaagcacgtaattacgtaccaaacctaacgtaattat	Protospacer
*****************************************