CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP019323	Lactobacillus allii strain WiKim39 chromosome, complete genome	19 crisprs	cas3,csa3,cas9,cas1,cas2,csn2,cas14j,DEDDh,DinG	0	10	9	0
NZ_CP019324	Lactobacillus allii strain WiKim39 plasmid pWIKIM01, complete sequence	1 crisprs	NA	0	1	2	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP019323_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019323_1

204878-205002

Orphan

Consensus_repeat	Method
AAACGTGTGCCAAAACGCAATTTTCTCCTGTATAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP019323_1

>merge|NZ_CP019323|1|204878-205002|CRISPRCasFinder
AAACGTGTGCCAAAACGCAATTTTCTCCTGTATAAATCTAAGAAATAAGGAATTGGTGATATACTTTTTTTCTACTCAGTTTTGTAGCTCAAACGTGTGCCAAAACGCAATTTTCTCCGTATAAG

>NZ_CP019323|1|1|204878-205002|CRISPRCasFinder
AAACGTGTGCCAAAACGCAATTTTCTCCTGTATAA	ATCTAAGAAATAAGGAATTGGTGATATACTTTTTTTCTACTCAGTTTTGTAGCTC
AAACGTGTGCCAAAACGCAATTTTCTCCGTATAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019323.1\|WP_120270328.1\|213185_213899_-\|NAD-dependent-protein-deacylase	unknown	unknown	gnl\|CDD\|238702
NZ_CP019323.1\|WP_076613737.1\|208543_208831_-\|Veg-family-protein	unknown	unknown	gnl\|CDD\|377636
NZ_CP019323.1\|WP_083685884.1\|209788_210358_-\|ribonuclease-M5	unknown	unknown	gnl\|CDD\|273019
NZ_CP019323.1\|WP_076613736.1\|207539_208382_-\|pur-operon-repressor	unknown	unknown	gnl\|CDD\|236414
NZ_CP019323.1\|WP_076613733.1\|203092_204508_-\|DASS-family-sodium-coupled-anion-symporter	unknown	unknown	gnl\|CDD\|279307
NZ_CP019323.1\|WP_076613735.1\|206076_207465_-\|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	unknown	unknown	gnl\|CDD\|184643
NZ_CP019323.1\|WP_076613734.1\|205083_206064_-\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_CP019323.1\|WP_076613730.1\|198914_200615_+\|glycerol-3-phosphate-dehydrogenase/oxidase	unknown	unknown	gnl\|CDD\|380303
NZ_CP019323.1\|WP_076613727.1\|196132_196573_-\|DUF1934-domain-containing-protein	unknown	unknown	gnl\|CDD\|378129
NZ_CP019323.1\|WP_157886429.1\|204611_204788_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076613726.1\|195441_196086_-\|DNA-directed-RNA-polymerase-subunit-delta	unknown	unknown	gnl\|CDD\|275360
NZ_CP019323.1\|WP_076613731.1\|201428_201848_+\|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl\|CDD\|376605
NZ_CP019323.1\|WP_076613728.1\|196638_197457_+\|lipoate--protein-ligase-family-protein	unknown	unknown	gnl\|CDD\|319742
NZ_CP019323.1\|WP_076613740.1\|210357_211122_-\|TatD-family-hydrolase	unknown	unknown	gnl\|CDD\|223162
NZ_CP019323.1\|WP_076613732.1\|201977_203009_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226326
NZ_CP019323.1\|WP_083686007.1\|200751_201351_+\|MmcQ/YjbR-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|225197
NZ_CP019323.1\|WP_076613729.1\|197456_198797_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
NZ_CP019323.1\|WP_076613738.1\|208911_209802_-\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP019323.1\|WP_076613742.1\|213908_214865_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076613741.1\|211121_213140_-\|methionine--tRNA-ligase	unknown	unknown	gnl\|CDD\|237028

Protein	Function_ID	Function_description	E-value
NZ_CP019323.1\|WP_120270328.1\|213185_213899_-\|NAD-dependent-protein-deacylase	gnl\|CDD\|238702	cd01411, SIR2H, SIR2H: Uncharacterized prokaryotic Sir2 homologs from several gram positive bacterial species and Fusobacteria; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins have been shown to regulate gene silencing, DNA repair, metabolic enzymes, and life span.	5.07079e-99
NZ_CP019323.1\|WP_076613737.1\|208543_208831_-\|Veg-family-protein	gnl\|CDD\|377636	pfam06257, VEG, Biofilm formation stimulator VEG. VEG is a family that is highly conserved among Gram-positive bacteria. It stimulates biofilm formation through inducing transcription of the tapA-sipW-tasA operon. The products of this operon are resposible for production of the amyloid fibre (TasA) component of the biofilm. Veg or a Veg-induced protein acts as an antirepressor of SinR - part of the major overall biofilm transcriptional control system - to regulate and stimulate biofilm formation. Veg is transcribed at high levels during both exponential growth and sporulation.	1.15095e-27
NZ_CP019323.1\|WP_083685884.1\|209788_210358_-\|ribonuclease-M5	gnl\|CDD\|273019	TIGR00334, Ribonuclease_M5, ribonuclease M5. This family of orthologous proteins shows a weak but significant similarity to the central region of the DnaG-type DNA primase. The region of similarity is termed the Toprim (topoisomerase-primase) domain and is also shared by RecR, OLD family nucleases, and type IA and II topoisomerases. [Transcription, RNA processing].	5.09059e-44
NZ_CP019323.1\|WP_076613736.1\|207539_208382_-\|pur-operon-repressor	gnl\|CDD\|236414	PRK09213, PRK09213, pur operon repressor; Provisional.	6.52023e-155
NZ_CP019323.1\|WP_076613733.1\|203092_204508_-\|DASS-family-sodium-coupled-anion-symporter	gnl\|CDD\|279307	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region. There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.	1.45768e-110
NZ_CP019323.1\|WP_076613735.1\|206076_207465_-\|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	gnl\|CDD\|184643	PRK14354, glmU, bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU.	0
NZ_CP019323.1\|WP_076613734.1\|205083_206064_-\|ribose-phosphate-diphosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	0
NZ_CP019323.1\|WP_076613730.1\|198914_200615_+\|glycerol-3-phosphate-dehydrogenase/oxidase	gnl\|CDD\|380303	NF033461, glycerol3P_ox_1, type 1 glycerol-3-phosphate oxidase. Glycerol-3-phosphate oxidase, also called alpha-glycerophosphate oxidase (GlpO), is an FAD-dependent enzyme related to the glycerol-3-phosphate dehydrogenase GlpD. Notably, GlpO releases hydrogen peroxide, which can contribute to virulence.	0
NZ_CP019323.1\|WP_076613727.1\|196132_196573_-\|DUF1934-domain-containing-protein	gnl\|CDD\|378129	pfam09148, DUF1934, Domain of unknown function (DUF1934). Members of this family are found in a set of hypothetical bacterial proteins. Their precise function has not, as yet, been defined.	5.03354e-11
NZ_CP019323.1\|WP_076613726.1\|195441_196086_-\|DNA-directed-RNA-polymerase-subunit-delta	gnl\|CDD\|275360	TIGR04567, DNA-directed_RNA_polymerase_subunit_delta, DNA-directed RNA polymerase delta subunit. Members of this family are the RNA polymerase delta subunit, as found in the Firmicutes and the Mollicutes. All members of the seed alignment have an extended C-terminal low-complexity region, consisting largely of Asp and Glu, that is not included in the model. Proteins giving borderline scores should be checked to confirm a similar acidic C-terminal domain. [Transcription, DNA-dependent RNA polymerase].	1.23427e-30
NZ_CP019323.1\|WP_076613731.1\|201428_201848_+\|large-conductance-mechanosensitive-channel-protein-MscL	gnl\|CDD\|376605	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL.	2.29229e-43
NZ_CP019323.1\|WP_076613728.1\|196638_197457_+\|lipoate--protein-ligase-family-protein	gnl\|CDD\|319742	cd16443, LplA, lipoate-protein ligase. Lipoate-protein ligase A (LplA) catalyzes the formation of an amide linkage between free lipoic acid and a specific lysine residue of the lipoyl domain in lipoate dependent enzymes, similar to the biotinylation reaction mediated by biotinyl protein ligase (BPL). The two step reaction includes activation of exogenously supplied lipoic acid at the expense of ATP to lipoyl-AMP and then transfer to the epsilon-amino group of a specific lysine residue of the lipoyl domain of the target protein.	9.12802e-42
NZ_CP019323.1\|WP_076613740.1\|210357_211122_-\|TatD-family-hydrolase	gnl\|CDD\|223162	COG0084, TatD, Mg-dependent DNase [DNA replication, recombination, and repair].	4.41556e-104
NZ_CP019323.1\|WP_076613732.1\|201977_203009_-\|hypothetical-protein	gnl\|CDD\|226326	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown].	1.1094e-35
NZ_CP019323.1\|WP_083686007.1\|200751_201351_+\|MmcQ/YjbR-family-DNA-binding-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	5.08558e-17
NZ_CP019323.1\|WP_076613729.1\|197456_198797_+\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	2.38119e-146
NZ_CP019323.1\|WP_076613738.1\|208911_209802_-\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	1.83046e-117
NZ_CP019323.1\|WP_076613741.1\|211121_213140_-\|methionine--tRNA-ligase	gnl\|CDD\|237028	PRK12267, PRK12267, methionyl-tRNA synthetase; Reviewed.	0

>NZ_CP019323.1|WP_157886429.1|204611_204788_-|hypothetical-protein
MLPLFWSFIFIVVILIFCLRNERYIRNVKRYKSDLMSIGIALGITAIILISFIMISGR
>NZ_CP019323.1|WP_076613733.1|203092_204508_-|DASS-family-sodium-coupled-anion-symporter
MKNRNKKIFYSIAVILVVLIIWFLPIPVGVKAAGWHTFAIFIGFILGCLLNLAPLAVLSIIMMAFLTISQAMPAEMIYAGFGNSAVWLIMFAFFVAIGFRTTKLGFRIAYYLIYRFGHSSLALSYVLTICDVIMAPFVPNTNARGAGVLYPITISLSKSLGSEPDDGTQNKIGSFLLLTSFHQNLIAGSLFLTAMATNPLALSMGKSVFHVSISWFDWLKYTSVPSLLALLIVPLVIYFIHKPELKKIPNAQNFAKEKLNEMGKVSTKEVIMILVFVLMIVLWSTTQFTNLDNTSIALLGLAILVVAGVIGLDDILSEKKVWNIFIWLPPLMAITPYLAQTGVIKWFKNIMSDSVSGLSLMSAFIVLALVYLYIHYFFTSVLVHMQALYIPFATVLVSLGANATMVIMMFAMLTCISPSTTHYGTGTASIYFATGYVSQKEWWRVGFIVSMTEFLIFMIIGLGWWKILGMF
>NZ_CP019323.1|WP_076613732.1|201977_203009_-|hypothetical-protein
MKKYKVIVWGLGNVGRAAIRMIQDKESLELVGAVDVDPKKIGKDSGEIFGFPKTGIVVINNIDDALKLDADIVLDYTPLVRDEKGGFTPSAEAICKILRAKKNVVTTLPIYYSQVTTPDLYKMINDAAKENNVSYLPTGLLPGAYASYIPTVLAGLMGRVDKIVVQSGEDDQHNFSSWVKVFGYGMDPDKFPQDKLKMGIASYYVSGVYELGERLGFKFDDMKIEHECFKAPVDLHPIFGTVKKGTISGHRFTMTGMVNGEEKASLIYVHKICDDVAKVPEIDNKIHIEGIPKTLDISIDGMMPLDESYVTSAAPSVNVIPMVVDGDSGFLQALDLKVVTPLK
>NZ_CP019323.1|WP_076613731.1|201428_201848_+|large-conductance-mechanosensitive-channel-protein-MscL
MFKEFQEFISRGSVVDLAVGVIVGAAFNSLVSALTTYIINPLLGVFIGQINLSEMKFEFFGASFLIGDFINALINFLIVMFVVFTIVKLMNNMRRDGSKSKFDESVEELDPQLEYLQQIRDLLRYQQLRDQEQDKKRRK
>NZ_CP019323.1|WP_083686007.1|200751_201351_+|MmcQ/YjbR-family-DNA-binding-protein
MNDNLLIYQTDILNQQFQLIITLNANSELTTKLIEISDGNEYRLHLDPSATGSFVNSVRNEFLGVINEIVDNCFDTDIFKNSQTKQVIEYVNDTYDTELEFLWEKFPNYAALRRLDNKKWYGLLMIVNAKKIGLDIDGDVEVLDLRIDTDKMEQTIDNKTFFPGYHMNKKHWYAIYLNDGISNEELFQRINNSYILADK
>NZ_CP019323.1|WP_076613730.1|198914_200615_+|glycerol-3-phosphate-dehydrogenase/oxidase
MKEFSEQTRLDNLRSMQNEELDLLVIGGGITGSGITLDAQTRGIKTGLVEMRDFASGTSSRSTKLVHGGLRYLKQAAINEVHEVGSERAIVYNNAPQITTPLKMMLPFYNGGTFGPFSTAIGLDVYDRLAQVKSSERKYMLDPQHTTDREPFIKSENLKGSGVYVEYRTDDARLTLEVVKKASELGALIANYTKVTDLLYDENQKVCGVIFEDQISGTTGEIHAKKVVNSCGPWVDEIRDMDGSNTGKHLHLTKGVHLVIDHENFPISNSIYFDTPFHDGRMMFAIPRENKTYIGTTDTTWNSDPKEPNITVEDVTYILAAANQMFDLPEQLTPDDVESGWSGVRPLIQEEGKSPSEISRKDEIFHSKSGLLSIAGGKLTGYRKMAEKIVNEVAFELSTETDYEYQSQQTKNLTLSGGEVGGDEGWDLYLEEMTELGIVTYKLERDDAQKLVQRFGSNVTDVYELIPDDDFKDNLPRVDWAMLQYGLKAEMVEHPIDYLLRRSSQMLFDINHMKDVEDPVIDYMSDYYGWDEATKKSMTDEVNEKLKLTDLSEIKKAYHEHIAKEV
>NZ_CP019323.1|WP_076613729.1|197456_198797_+|HD-domain-containing-protein
MTYKLEMLPREKVFRDPIHNYIHVQHRVILDLINTKEFQRLRRIKQLGTASFTFQGAEQSRFTHCMGVYEITRQICDNFKRNYPTKNPGDGLWNDDERIVALCAALLHDVGHGPYSHTFEHIFNTDHEQWTQRIITSKETEINQVLRQVSDDFPEKVASVIAHTYDNPQVVQMISSQIDADRMDYLLRDAYFTGTKYGMFDLTRILRVMRPYKNGIAFDYDGMHAVEDYVLSRFQMYQQVYFHPVSRGMEVVLTKLLQRAKDLYEHNHMNDFEMPSLLIPFFENNVGIDDYLSLDDGILNTYFTLWQNYPDEILKDLSYRFLSRKPLKSAEYDQETEKILPKLADIVESAGFAKEYYTSTNTSYDLPYDVYSPNSNKNRTQIEIMRDDGSLIELSTISGLVNALTGKISGDERFYFPKSMLVEHPDDIFSNTYEQFQEHIFNDEII
>NZ_CP019323.1|WP_076613728.1|196638_197457_+|lipoate--protein-ligase-family-protein
MNNTILLYNQEITKDEDMLKPFADTGAILKFTSENSIPVAHFWTTPPTVILGLQDQRLKNIAGGMKRLEEKRYLYYVRNSGGLGVVTDEGILNFTLFLPNKNNITIDQAYEQMHQIMQKTFSDKIKTGEIVHSYCPGTYDLSIDGKKIAGISQRRSGNAVAIMAYISVTGNQKKRSQLMKDFYEISNYPLHKKITYPNIDIHCMTNLDEILNHPLTINQAKEQIIETLKLSGYQLNQNEFNIIRESLPYKDAYKQTMDDLIYKNQKLLSEEK
>NZ_CP019323.1|WP_076613727.1|196132_196573_-|DUF1934-domain-containing-protein
MENNSVNVNVELNMETLQAGEITHTKIVEPGKFTKIGKSMYLRFDESLDNNDKASILVKVGDDGEIHLKRVAKSTNLASLLYFTHKKHNSGHLQTEYGVLPLGTFTNDSVVEVINKPLSGKINIDYDLIYDNNIVGNYKFRLIFSA
>NZ_CP019323.1|WP_076613726.1|195441_196086_-|DNA-directed-RNA-polymerase-subunit-delta
MEFEKLKNQNKDELSLIEVAYEILDTSNKEAMNFSNIVNKIQDYLGRSDADVKDSLPQFYTDLNNDGSFLSLGENVWGLRKWYPFDSVDEEVNHPEDNGTENTHKAAQKVNAFMSDDAEDDDVVDYDDADLNVTDMDDDDDESDESSSNGPDLSKFTNSDLSVDDDSDDEQDTGLDDGIEGQLSEFDADDDDEDSDIDLSDEDDDDDSDEDDDI
>NZ_CP019323.1|WP_076613734.1|205083_206064_-|ribose-phosphate-diphosphokinase
MSYQSNERPMKIFALNSNKPLAEKIAKEVGIPLGKSSVTRFSDGEIQINIEESIRGAEVFLIQSTSAPVNDNLMELLIMVDALKRASAHLINVVIPYYGYARQDRKSRSREPITAKLVANMLERAGVNRVLALDLHAAQIQGFFDIPVDHLMGAPLLADYFLTNHLEEDAVVVSPDHGGVTRARKLAEFLKTPIAIIDKRRPRANVAEVMNIIGNVKGKRAIIIDDMIDTAGTISLASQALIDAGATEVYACCTHPILSGPAIERIEASPIKKLIVTDSINLPKEKIIDRMVQVSVGPLIGDAIRRIHDNEPVSPLFDNRFKANKK
>NZ_CP019323.1|WP_076613735.1|206076_207465_-|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU
MSNRYVIILAAGKGTRMKSKLYKVLHPVAGKAMVDHVLTQVEKMKPAIVETVIGSGAEKVRDLLGDRTKYALQEEQLGTAHAVLQTEDVLADKEGTTLIVNGDTPLFTAETFEKLFNYHEKQQAAVTILTAHADNPFGYGRMVRGVDGSVSKIVEQKDATDEELKIQEINTGVLCFDNKLLFDNLHNVKNDNAQGEYYLPDLIGMFKKQNKKVSAYQMADLSESMGVNDRVALSHAEKLMQTRINEFHMREGVTIIDPNNTYIDADVKIGSDTVIEPNVKIFGKTVIGSNCLIGSGSRLEKAVIEDNVKIISSTIESAIMHEGSDIGPNSHLRPKAEIGKEVHVGNFCEIKNAKIGDRTKVGHLTYVGDATLGTDINVGCGVVFVNYDGVKKWHSNIGDHSFIGSNSNIVAPVEMSDHSFIAAGSTITNDIPKHAMAIARQRQTNKEDFWDRLPLSKSEDWE
>NZ_CP019323.1|WP_076613736.1|207539_208382_-|pur-operon-repressor
MKTRRSERLIDETRYLLERPHTLISLAFFAKRYESAKSSISEDLGILRRTFMIRGIGALETLPGAGGGVIFTPGISKEEATDFITTTTKRLEEPDRILPGGYLYLTDLLADPEVLRTIGRMIATQYSQSSIDVVMTVATKGIPIAQSVANFLNIPFVMVRRDSKITEGSTISVNYASGSSDRIEKMELSKRSLPEGSRVLVVDDFMKGGGTINGMRSLISEFNAIFAGATVFAENINVRSEFRDTKVTSLFKVNQIDTVNRILKMEPGDYLAKTDFSYFE
>NZ_CP019323.1|WP_076613737.1|208543_208831_-|Veg-family-protein
MPTSLKSIKSRLDSHLGENLTVVAQAGRKKVIRRRGTLAETFHSVFVVDLDQDENSFERVSYSYADLLTKSIDITFDSEAANEDSSADTEVADAE
>NZ_CP019323.1|WP_076613738.1|208911_209802_-|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MTLNRLSISDPIRTNDILRKYKLRAKKSLGQNFLTSEKVLNEIVDASKLKSDEIAIEIGPGIGALTEKLAEVAEKVYAFEIDQSLIPVLEDTLSYYDNIEVFNEDILKVNLDDFVKEHHLEGKTIKVVANLPYYITTPIMLSLINSDYPFQALVLMMQKEVAERITANPGHREYGSLTIAVQTQMDAKIACIVGKESFIPRPKVDSAVAVLERLPKEKIDIEDPEFFNKLIRSSFAQKRKSLMNNFLNWLGRTDENREIIKEVFKDCEIAENARGEQVSIEQYKKLATDLQQRIKK
>NZ_CP019323.1|WP_083685884.1|209788_210358_-|ribonuclease-M5
MKIKEIIVVEGKSDTNRLKDCLGEVDTIETRGSALSDETIERIKAAQQKRGVIIFTDPDFNGNRLRTIISKVVPDAKQAFLPRNKAVPKKSDGSLGIEHAKDEDIKKALASIYTMSDLTDDYSTNDMIDLGLIGDVSSQKRREFVGDDLKLGYTNAKQFLNRLNMQQVSPQKLLAAVEKFDKGSTHDTK
>NZ_CP019323.1|WP_076613740.1|210357_211122_-|TatD-family-hydrolase
MKIFDTHTHLNDPAFAGKTQEYIDRAAEFDVDEMAIIGQNEDYNIEAIRLAQNYKPLHAVIGWHPEFASEYNEEQLVNQIKLPEVVAIGEIGLDYHWSENPESSIQKATLIKQLDVAQQYNMPVSIHCRDAFEDMYEILKNHDMSKSGIIMHSFNGNLEWLNKFLDLGLMISYSGVVTFKNAKEVHESAKNTPLDRLLVETDAPYLAPEPYRGHQNEPGYTRFVLDAIAKYKDIDPDIVAQHTFENSYRVYNIK
>NZ_CP019323.1|WP_076613741.1|211121_213140_-|methionine--tRNA-ligase
MTQDKKTFYITTPIYYPSGKLTIGNSYTTIAADTLARYKRNEGFDVFFLTGTDEHGLKIEQKAEAKHMKPQEYVDMMASDIKKLWKLLEISNDKFIRTTDDYHVAAVQKIVEKLIAQGDIYLGEYTGWYSVDDEEYFTESQLAEVYRDKDGKVSGGLAPSGHEVTLVKEPSYFFKMGKYADRLLKYYEDNPTFIEPEIRKNEMVNNFIKPGLEDLAVSRTSFTWGVPVPSDPKHVVYVWVDALLNYITALGYMSDDDSLFKKYWPANVQFVGKEIVRFHTIYWPIILMALGIDLPKQVFGHGWLLMKDGKMSKSKGNVVYPEMLVNRYGLDSLRYYLMRAMPFGNDGMFTPEDYIDKINYDLANDLGNLLNRTISMINKYDDGKVVSVKAVTEFDTALEGAYETTLTDYRKHMDKFEFPDALASVWAFISRANKYIDETKPWVLAKDADKKEELDSVLGHLAEGLRLIALLISPVMTQSPIKMFAQLGLDYDNDKSLKFGDTVVGKTVTSDPTPIFPRLDAKEEVEYIKNKMAEEKAKNGSGKLSKSAQAKAKAQSESEDEYPKEISFDDFSKVKMVVTEILDVKRAANADKLLQFTLDDGTGIDRQILSSMYEFYPNFKELIGKKVVAVINLKPRKIRGEWSNGMLLSTEAGDDVKLVLVDNSHKNGAILG
>NZ_CP019323.1|WP_120270328.1|213185_213899_-|NAD-dependent-protein-deacylase
MSDEISEFKDLLKAAKFVTFLTGAGVSTPSGIPDYRSKNGLYKREKYDFPPEYMLSHENLLKNPEIFHDFTVHNMYFPDALPNIIHKKMAEISNDKGAIVTQNVDKLHTKAGAKNVVEFHGNLYDDIHCLTCGKQFDYKYYMKDYIHHEDNGIIRPGTTVLYGENINPKNVEKAVEYVKKADLLVVVGTSFKVYPFAGLLNYASSDAKLVVINKEDIDIDSSGLAISDDAVNVFSQL
>NZ_CP019323.1|WP_076613742.1|213908_214865_-|hypothetical-protein
MERIDINNLSDNIVNQISKIEQLTDNKVEIYSDFSDHQFLTLDQASHETKHNKITVTITNEKYSEFVLLHELYHVELENSGEPLISCAVTSGDRDVDGRIISTANSLFESLEHSLVVQKQIDDGSYTDEIKKEYLKGIDHALNPNVQLDPDNMRFYRSLIIFDAIIFGQHSEDSDWKLNFPVSFKVASKLVKQVEDNDLTKPFQFRRALINVLEEYNDLIISRGYESMHYHEFLNVTPIVSERQLRLNLNQTYNIKHSAFKNRSTGDDAFALIAINDGQSVATLNFDSTKVNPEFYKAYYQRTLKETFAKNGIKYQLR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP019323_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019323_2

231543-231640

Orphan

Consensus_repeat	Method
TTTTCAGGGTCTACATCGTTGTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP019323_2

>merge|NZ_CP019323|2|231543-231640|CRISPRCasFinder
TTTTCAGGGTCTACATCGTTGTCTTCTTCCGTATTGTCTGATCCATCTGGCAATTCACCCGGTATTGTTACTGGCTTTTCAGGGTCTACATTGTTGTC

>NZ_CP019323|2|2|231543-231640|CRISPRCasFinder
TTTTCAGGGTCTACATCGTTGTC	TTCTTCCGTATTGTCTGATCCATCTGGCAATTCACCCGGTATTGTTACTGGC
TTTTCAGGGTCTACATTGTTGTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019323.1\|WP_076613755.1\|228841_229084_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076613766.1\|242488_243676_-\|Firmicu-CTERM-sorting-domain-containing-protein	unknown	unknown	gnl\|CDD\|200396
NZ_CP019323.1\|WP_076613752.1\|224597_225041_-\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NZ_CP019323.1\|WP_076613760.1\|235902_236598_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076613750.1\|222350_223073_-\|DUF4811-domain-containing-protein	unknown	unknown	gnl\|CDD\|374344
NZ_CP019323.1\|WP_076613751.1\|223072_224566_-\|multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP019323.1\|WP_076613753.1\|225154_226180_-\|tryptophan--tRNA-ligase	unknown	unknown	gnl\|CDD\|183400
NZ_CP019323.1\|WP_083685887.1\|240495_241851_-\|putative-glycosyltransferase,-exosortase-G-system-associated	unknown	unknown	gnl\|CDD\|132155
NZ_CP019323.1\|WP_083686008.1\|243881_244745_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223730
NZ_CP019323.1\|WP_076613763.1\|238487_240071_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274774
NZ_CP019323.1\|WP_076613765.1\|241850_242450_-\|exosortase-family-protein-XrtG	unknown	unknown	gnl\|CDD\|188282
NZ_CP019323.1\|WP_076613757.1\|230027_231095_+\|acyltransferase	unknown	unknown	gnl\|CDD\|225813
NZ_CP019323.1\|WP_076613754.1\|226477_228742_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|226482
NZ_CP019323.1\|WP_083685886.1\|240063_240492_-\|6-carboxytetrahydropterin-synthase	unknown	unknown	gnl\|CDD\|132156
NZ_CP019323.1\|WP_076613762.1\|237624_238293_+\|metal-dependent-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224240
NZ_CP019323.1\|WP_076613761.1\|236964_237486_-\|DUF308-domain-containing-protein	unknown	unknown	gnl\|CDD\|225786
NZ_CP019323.1\|WP_076613749.1\|222012_222216_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076613756.1\|229252_229918_-\|CAAX-protease-family-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076613759.1\|233443_235396_-\|TetM/TetW/TetO/TetS-family-tetracycline-resistance-ribosomal-protection-protein	unknown	unknown	gnl\|CDD\|223556
NZ_CP019323.1\|WP_076613748.1\|219330_221682_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP019323.1\|WP_076613765.1\|241850_242450_-\|exosortase-family-protein-XrtG	gnl\|CDD\|188282	TIGR03110, exosort_Gpos, exosortase family protein XrtG. Members of this protein family are found in a modest number of non-pathogenic Gram-positive bacteria, including three species of Lactococcus and three paralogs in Clostridium acetobutylicum. This protein appears related to the conserved core region of a family of proposed transpeptidases, exosortase (previously EpsH), thought to act on PEP-CTERM proteins. Members of the seed alignment include all exosortase proposed active site residues. However, in contrast to canonical exosortase (TIGR02602) and archaeal (TIGR03762), and cyanobacterial (TIGR03763) variants, this family has not yet been matched to a cognate PEP-CTERM-like sorting signal. This protein is assigned the gene symbol XrtG (eXosoRTase family protein of Gram-positives).	7.9984e-68
NZ_CP019323.1\|WP_076613766.1\|242488_243676_-\|Firmicu-CTERM-sorting-domain-containing-protein	gnl\|CDD\|200396	TIGR04145, hypothetical_protein, Firmicu-CTERM domain. This C-terminal domain is found only in the Firmicutes, where its presence is sporadically distributed. Proteins with this domain are most conserved in the C-terminal region, where the pattern of ending with a transmembrane domain resembles both the LPXTG (sortase target) and PEP-CTERM (exosortase target) domain structures. However, members occur exclusively in the presence of an exosortase-like protein XrtG (TIGR03110), a putative glycosyltransferase (TIGR03111), and a 6-pyruvoyl tetrahydropterin synthase-related protein (TIGR03112).	2.85087e-12
NZ_CP019323.1\|WP_076613752.1\|224597_225041_-\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	9.66532e-12
NZ_CP019323.1\|WP_076613753.1\|225154_226180_-\|tryptophan--tRNA-ligase	gnl\|CDD\|183400	PRK12282, PRK12282, tryptophanyl-tRNA synthetase II; Reviewed.	0
NZ_CP019323.1\|WP_076613751.1\|223072_224566_-\|multidrug-efflux-MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	7.8452e-99
NZ_CP019323.1\|WP_076613750.1\|222350_223073_-\|DUF4811-domain-containing-protein	gnl\|CDD\|374344	pfam16069, DUF4811, Domain of unknown function (DUF4811). This family of proteins is found in bacteria. Proteins in this family are typically between 188 and 241 amino acids in length. There is a single completely conserved residue Y that may be functionally important.	6.18629e-49
NZ_CP019323.1\|WP_083685887.1\|240495_241851_-\|putative-glycosyltransferase,-exosortase-G-system-associated	gnl\|CDD\|132155	TIGR03111, glyc2_xrt_Gpos1, putative glycosyltransferase, exosortase G-associated. Members of this protein family are probable glycosyltransferases of family 2, whose genes are near those for the exosortase homolog XrtG (TIGR03110), which is restricted to Gram-positive bacteria. Other genes in the conserved gene neighborhood include a 6-pyruvoyl tetrahydropterin synthase homolog (TIGR03112) and an uncharacterized intergral membrane protein (TIGR03766).	0
NZ_CP019323.1\|WP_083686008.1\|243881_244745_-\|alpha/beta-hydrolase	gnl\|CDD\|223730	COG0657, Aes, Esterase/lipase [Lipid metabolism].	2.18076e-31
NZ_CP019323.1\|WP_076613763.1\|238487_240071_-\|hypothetical-protein	gnl\|CDD\|274774	TIGR03766, hypothetical_protein_lp_2141, conserved hypothetical integral membrane protein. Models TIGR03110, TIGR03111, and TIGR03112 describe a three-gene system found in several Gram-positive bacteria, where TIGR03110 (XrtG) is distantly related to a putative transpeptidase, exosortase (TIGR02602). This model describes a small clade that correlates by both gene clustering and phyletic pattern, although imperfectly, to the three gene system. Both this narrow clade, and the larger set of full-length homologous integral membrane proteins, have an especially well-conserved region near the C-terminus with an invariant tyrosine. The function is unknown.	1.66707e-148
NZ_CP019323.1\|WP_076613757.1\|230027_231095_+\|acyltransferase	gnl\|CDD\|225813	COG3274, COG3274, Predicted O-acyltransferase [General function prediction only].	3.07627e-16
NZ_CP019323.1\|WP_076613754.1\|226477_228742_+\|AAA-family-ATPase	gnl\|CDD\|226482	COG3973, COG3973, Superfamily I DNA and RNA helicases [General function prediction only].	4.27665e-119
NZ_CP019323.1\|WP_083685886.1\|240063_240492_-\|6-carboxytetrahydropterin-synthase	gnl\|CDD\|132156	TIGR03112, 6_pyr_pter_rel, 6-pyruvoyl tetrahydropterin synthase-related domain. Members of this family are small proteins, or small domains of larger proteins, that occur in certain Firmicutes in the same regions as members of families TIGR03110 and TIGR03111. Members of TIGR03110 resemble exosortase, a proposed protein sorting transpeptidase (see TIGR02602). TIGR03111 represents a small clade among the group 2 glycosyltransferases. Members of the current protein family resemble eukaryotic known and prokaryotic predicted 6-pyruvoyl tetrahydropterin synthases.	1.1067e-37
NZ_CP019323.1\|WP_076613762.1\|237624_238293_+\|metal-dependent-transcriptional-regulator	gnl\|CDD\|224240	COG1321, TroR, Mn-dependent transcriptional regulator [Transcription].	2.23073e-43
NZ_CP019323.1\|WP_076613761.1\|236964_237486_-\|DUF308-domain-containing-protein	gnl\|CDD\|225786	COG3247, HdeD, Uncharacterized conserved protein [Function unknown].	3.1122e-06
NZ_CP019323.1\|WP_076613759.1\|233443_235396_-\|TetM/TetW/TetO/TetS-family-tetracycline-resistance-ribosomal-protection-protein	gnl\|CDD\|223556	COG0480, FusA, Translation elongation factors (GTPases) [Translation, ribosomal structure and biogenesis].	4.24065e-113

>NZ_CP019323.1|WP_076613757.1|230027_231095_+|acyltransferase
MKKNNRIFFLDFIRVIAIFLVIFIHVSAIDTTLNIGSGQWQITKILNYFAHISVPMFFMISGALLLNSKKTKSISYTWKQRIPRVVIPFILWSIISPIVVGIYAHSLSATNVLSSIKLMLYQPTSPTLWFMYPLIGVYILSPIIREFVENASKKMLLYTMLIWLITNSLLPSIAVMFPKSNAFTIYPVANFFLVGGFVGYFILGYLMTQINVNKYSNISLIIAMLIFGLSGNFISELVPKIFDAFNGYYVTSIFIPLMSIPAYILLQKWGQNIKSEKVISVFEFLAPLVFGIYLIHNLLILYLEPWFMSILPFGGILSTFIRYIAVASLSTLIIWIISLIPGLNYLLTGTHKKRL
>NZ_CP019323.1|WP_076613756.1|229252_229918_-|CAAX-protease-family-protein
MRVGESPRIDLVRYLIWIIFSVITLSLKNITATDKGLNIILMIIFFAVGIVFTFLMTRRYLRERRSFSDNPTGFMSSLISNIGLVTLMIILVCALRLMVSYLQVTGKLPSFQNDDVASSDQKVFIFNMIANIFIIAIQQQLVQTGFFFNYFFRKSTAGNAVIGIVLSGVIGGLISLPGSLLQFFMMMALGWCYALTYLYTQDEKMAMLVGLISAIVGTILI
>NZ_CP019323.1|WP_076613755.1|228841_229084_+|hypothetical-protein
MYPRKIKIAPIIKVNVNGITIFLTNSASNMTRNKKTSMDRFLANFTIKTISNIWKMNIAIEAFDNPIIIAAFYRNINPSM
>NZ_CP019323.1|WP_076613754.1|226477_228742_+|AAA-family-ATPase
MTINETKEEEQTRVSKIAQKIDNKIAQTTENLEKAHTETHNIYRNYGENIKVNTFEVDDKMETNASVQQQKQLVTLAVENENILESNKQQLENLQGSPYFGRIDVVEDNEEDTLYIGTSTLQDDDGEFLIYDWRAPISGIYYNGILGKVSYSTPNGKAEVDLKKKRQFQIINNKIRTMFDTNETVGDEILQSVLSEYSDEYMKNIVATIQHEQNTIIRDTHSDVLLVQGVAGSGKTSAILQRVAYLLYHSRSTLDADKIVLFSPNRLFSNYISEVLPSLGERNMRQVTLNEFISFRLTGIQVETLFDRYEKDERNLPQTTIDIRLFKESADFLTTLEQTEKENKEHTLYFEDIIFEGKPFFTKEEISEIYNRQNTAFSIPDRFLKTKNILIKQLKRRIHNDRDEDWVQAEIDNLNDEDFQQIITDNNIEESTNQRSIIAEEFLKERYAPIYNALINNYFFDPYKEYVFLLTNMNQDIVSNKVWQTMIESIDQNVEAHKLGLSDAIAILYLRDFITDSGTNHNIQHIFIDEIQDYTMAQLKYISHSFPNAKMTLLGDRAQDVLTSSYRNKDVIDAICELYQGKKVTTINLNQSYRSTAEITDFAKSLLPNAKEVKSFSRKGEIPSIKVFDDETDYYMGLKQTARELTDKYETVAILTRNQAQAEQVYTHFGDESLVTLVDADFRSVPKGILVMPIYLAKGLEFDAVIGHDISAANYPDSRSRDTLYTICTRAMHNLTLCVEKVPSPLLEHTKITN
>NZ_CP019323.1|WP_076613753.1|225154_226180_-|tryptophan--tRNA-ligase
MTTNTILSGDRPTGKLHIGHYLGSLHNRVKLQNEGKYKLFIMIADMQALTDNARNPEKIRNSLIQVALDYLSVGIDPAKSNILIQSQIPALNELTMYYLDLVNVSRLERNPTVKSEIKQKGFGQSIPAGFLTYPVSQAADITAFKADTVPVGDDQEPMLEQTREIVRTFNNTYNTNTLVEPKGIFPPKGQGRLPGIDGNAKMSKSLGNCIYLSDPEDVVTKKVMSMYTDPDHIHVEDPGKIEGNTVFTYLDAFAEDKKMVEQLKEQYQAGGLGDVKVKRYLNDVLQEVLKPMRERRAEYEKDIPSVYQILKDGSDRANEVANQTLSEVRSAIGVNYFDNLK
>NZ_CP019323.1|WP_076613752.1|224597_225041_-|winged-helix-turn-helix-transcriptional-regulator
MDDYDLIGFAVRFMMQRKRILSVFLKGRNLNLADCIILMLSIKHPEYNQEKIGEVTLFDGAIIARSLKKLENQDLVTRKVDKSNRRRKIVQITETGKEFGNKLMAAFKDSNETIYSGITEDELEQLDVILAKVYTNLDKVKIPDSNK
>NZ_CP019323.1|WP_076613751.1|223072_224566_-|multidrug-efflux-MFS-transporter
MANSSAQVDVNGKAYNRNLLVLVLLVGTFCTVLNGTILTTAFPTLMKEFNVTTSAVQWLTTGFLMVNGIMIPVTAWLSNNFSNKILYIVAMSTFLVGTIMCFTAPNFQTILAGRLVQAVGVGITMPLLQVIMLSIFPPAKRGTAMGLSGIVIGLAPAIGPTLSGWIIDNFTWRDLFGMIIPIVIIVIILAFAFMRPVIETKRTKLDVLSLLLSTFGFGSVLYGFSSVGDKGWGSPIVLGTIIGGIIIVILFGYRQLKMDTPFLELRVFKQKRFAVAAALSSVTNMAMVGVEMILPLYLQIVKGMSAFHSGLTLLPGAILIGIMSPITGRAFDRFGAKDLARMGMFLLTAGTIPFLFLTKTTPVLDIIILYMIRMFGISMVLMPVTTDGMNSLPLHLMSHGTAVNNTVRQVFSSMGTAILVSVLTNVTNNLKPGKSILTKTPLKYENDFFNATLSGYHAAFGIAILFCVVALVISFMIRDSHKSKDVDLNKVEMAGDK
>NZ_CP019323.1|WP_076613750.1|222350_223073_-|DUF4811-domain-containing-protein
MIIVLILLSVVLAFYFAVFIQNKKVGYSLMAVSIVVFLCGLVMLISNEYNHFGMHKVTSEKTEQIQTVQKGNNILLYKELGTSGKEDVYIYRRPETAKAKNPDHTKAKLNVTNKVKKGASSNTLAQKTTRWEYKNGFYSFLFGISGNDKEFVKQTNTFHIGDDWLVLSTTQAAKLSKEMKSKKVQAQMKTQGEAYVKAALTTAMTQNPTMSASQQKQVMKQAQKEFKAQAMAKVVKELTK
>NZ_CP019323.1|WP_076613749.1|222012_222216_-|hypothetical-protein
MKNNTKLFLYCGALLAVLSVGLVTTVSAATVPSIDTDTSIPEPEKVGTQVDTDVNVANNAIHEISRA
>NZ_CP019323.1|WP_076613748.1|219330_221682_+|hypothetical-protein
MRIHIKFRVFYLIFFFFISLIFCATKTVNAADIDDGITNWKVSSYNEVQSLPIGGNLSLGYAFGLAADKNYQVADHLDSTMTTDSVAISTDNAYYSKINTFLNNNGKYISAIFQSGITGTGGLPQQSVSLSSPDFMIVPNNNSSTATGKDYSLLTNALKNKQYYIGTDDNGNKAFKIVGDFQRNDSFGNFNLKAEILLRASQSNSAVVYRELYLQNNTTSTQSFGVLYGEDTYLNDSDIVAIQDLGDQSGFFIQNGNYKLMVSKNVPDGPSNYIGQENNTGLNWLAGFIPANFSGTGAEAKSFNYGDNIMNKRGDSTYTLKWPYTTLAPSQTAHYASTIGVTEAPYSLPVAGKTYTNETSSDKLNRVGDKLKFNLKIGNYGFNSKWSYDDLVDKIPDGLQIDTSTIKMTTASGTQNISSDVYDSSSKTLTFYPSVLLTDGQSATISFEATITESASNQTLSNTANFTGHDAINTSDGSKTYNASVDIPVEKSSFEYTFTNLVKNETKGDSDFSEKTDAVAGDIVDYQIKFGTNSDSKDYFTGGQLKTSIPDGMTFVSGQIIGSDGWTGSASPDSNGNFSLGIGNVGNGTFATLNFKAKVSQASAGVITSTANMSGTTSTGISTGDMVSNVAQVDISDVVGFTETPRLIDFGTTNFAGKEKSLTNVATTGQLIVNHPTEDNYYVQVGFTNANTEQMVNSNGDALSPSADGLMFLKQRVDSDTDTGTWTPIPSNPSSIPIKSGTFNGSQNLTNYIGVGAWKLYLGSNTKSGNYSGTLTWSLTDAP
>NZ_CP019323.1|WP_076613759.1|233443_235396_-|TetM/TetW/TetO/TetS-family-tetracycline-resistance-ribosomal-protection-protein
MKHIVTGIVAHVDAGKTTLSESLLFKSGQLRKIGRVDNGDTFLDSDKLEKKRGITIFSHQASLKFGDTQLTLLDTPGHVDFAAQTEQVLDVLDYAILVISATDGIQGYTRTLWRLLKHRNIPVFIFVNKMDANGVNKSEVLKSLQETFHGCIDFDEDLSEESYEEIAMQDDDVLEDFLDSGEVSEDVIREMIKQRKIFPCYFGAALKQDGVDNFLQGIDKWTIESSYQQDFGAKVFKVSHDDKGERLTWLRVTGGVLINKSIIVDEQKANQLRIYNGSKFTTSQEIVSGGICTIPGLVDTFPGQGIGVEKDSGAPEIQPVLNYSLDVNGNDVHECLKSLRQLEDENQQLHVTWSSHLQEIHVQIMGKVQLEILQQEMLDRFNLDIRFGASSILYKETVTKAVEGVGHFEPLRHYAEVHLLLKPNDGKGLIFNSDCDLEVLSKNWQHQVLTNLNAKEQLGVLTGSPLTNMDITLVGGRFSNVHSVGGDFREATWRAVRQGLMELKRSGSCQLLEPWYRFRLEVNATQVGRAMNDIQKMSGSFDTPKSGNIAGNTVLTGIAPVSEMQDYAQEVQAYTHGQGEIEYMVDGYNPCHNTDEVVEKFDYDPVSDLDNTPGSVFCAHGAGYPVKWEDVPNMAHFPYVYTQAQLEKIN
>NZ_CP019323.1|WP_076613760.1|235902_236598_+|hypothetical-protein
MGSEFSFLHFAIVLDKKDNSKKRTLTVIPLTSKQKSGRFPLGKEIFNQTITIINSRIEENEDKHRRIQQNINKITNEIADLVNDFLDAIIENNCDYKEELKQFKISDDEEDRFETNNLLKELTKYVEKNNHLEYSDELLPKFNEQLELMANESKNLSKDASQLNKETLDLQKVIDIYQGYNKNSYVRLTDVTTISKFRIKRLNRFDSSGKIQLSSEQMKVISDELMKLYIS
>NZ_CP019323.1|WP_076613761.1|236964_237486_-|DUF308-domain-containing-protein
MNYTKRRFDWFGFIIGLISLYAGYLVLWYPLGSLSTIAAIFGVYVILRGIYQLWFGSQMTRFLGVRSGWTVFSSIVDILIGVLFIAHLNFGVMVFIYMFAIWFLIDAIFQLTTSRLYHFFGKKYYIAIVILAILNLIFALILLFNPILAGGVIIFFLAFFFITTGIVEIIEAF
>NZ_CP019323.1|WP_076613762.1|237624_238293_+|metal-dependent-transcriptional-regulator
MSPNKENYLKTIYELNYDFTKITNKRIAEIMDVSAPSVTEMLNSLSADGYLTHSPYNKITLTPKGNKISEKLVKTHRLWEVFLNRCLDYPVDNVHHHADDLEHSSDKDLMDHLNEFLDFPQRCPHGGIIPGNGKGETDADDKLLSMIPDGQTVQIVRVSDNYDFLQYFSSLNMRIDDTIKIIKKEKFDNSLVLKKEDGSSVTIGAKAIDYIFVEDRPDMETK
>NZ_CP019323.1|WP_076613763.1|238487_240071_-|hypothetical-protein
MRRFYNFSHTIINIFWRVLFFLTLFFALTSSNIIIGDNDTFGTSTTMVTSGLVILIIAIAVLNYAYPKIHAWFSNVFVKHQLITSGLMLLAVLIGQVVFVSYVHPVAGFDAGALHYAAISAEHAKEVNTIAYYSLYPNNILSMLGMHWLTEVSGQTSWQFFDYVTLALVDLSAIFNLLSVVVVRKRLLGVAMYIHCAWLAVFPSIIMPYTDAWVLPFISLFLLCYFLMRNSLSFKNSLAQLIFVLSSIGCGVSLVLTYFVKPSAIVPAIAIVIIELLTWLVQKKHFTLKGTILTFSVLILVGGSAGLTYKTASNVIQNQTYIKIDKSLSIPPIHFMAMGVYGEGGYNTKQAVEMSVLRTKKEKTDYSIEMLTRRLKKLGPLGYLKFLAMKQRNNTADGTFGWLKEGHFFRDNQKTNNKGISNKIKNYVYLYGKHIADFRFAAQLWWIALLMIIALGFGPRQNIIQILRLSMVGGFLFLLLFEGGRSRYLIQYLPCLLLLGTFSFERAVENVKRLLGWYEVKLDESEK
>NZ_CP019323.1|WP_083685886.1|240063_240492_-|6-carboxytetrahydropterin-synthase
MIKQRSYKIKSYVNASHAVRWKSGTGKKHNHTWEIVCELHAFEGMVSFFDIEKSLSAAIDELSGKYLNDLPEFKVINPTVENVTEYLFDKVDGILKDNGAMLLRIEVSDSPTRSFCIDVTGRNIPTESEIKSEQKKQDESDA
>NZ_CP019323.1|WP_083685887.1|240495_241851_-|putative-glycosyltransferase,-exosortase-G-system-associated
MYWINLALSRMGFWITWALIPIVVEIIPAIVSTIKLMYMHLHEPKLEAPGKWPWVSIIVPVYNSEDTLFACIESINNQTYTKKAMQIVLANNQSTDDSFGVYAKAQNTFPELILRYVNTDNGKAKALNTAIYESIGNYVINIDSDGVLEPNAVKNMVLRFENDPSIAAMTGAILPNSSMVQNVKGFWHRILAKNEYYEYAQAFLSGRTIESSRDQLFTMSGAFSAFRREVLMETFLYDIDTIGEDTDMTFQIRTRLGKKVVICSNAIFYCEPISGLNELYTQRQRWQRGEMEVAHNYMAKTAGLKEFFNNFLVRRMIIDHTFSFPRMIWTFASFVLIAFGYSPIILLLSYILIYALYVFVGLINFISVGILLREYHDEQHYYLKLWWVVMTLPVYMFICSWIRLIGIINGMTTRSSWQMKNINTEITQLQSVFKDDVKTVKEQRSKDREGK
>NZ_CP019323.1|WP_076613765.1|241850_242450_-|exosortase-family-protein-XrtG
MNVYILLGIVVWLYVLSVLKRAQLSAFFFIVGSAGLFFILTAISRPYWVWFFTHAVIHGVDLFSRITNWSNVMLKTGLVYITNGHNPVVMSIDYECSGIIETCAFIALTVFFPMYKRKEKVFYAIFGLVFIYLSNVLRLIIVITIVHFGGGSAFFLAHSVIGRLVFYVLVIALYYNVFTYSQLTRGIYREFLDWGHHKQ
>NZ_CP019323.1|WP_076613766.1|242488_243676_-|Firmicu-CTERM-sorting-domain-containing-protein
MKLHKMIMVGALALGLSGLTVFTNSATVNADDTSSNIAIDGQYSDWQSTKLTTGYNGGIAIVGDGQYADIYVHMQYGDVPSSGYVLSINGKDYYMSSKSSDGSSGDSKQVSFTGGKWDGGDQYGTVGTGYVSQDNGSGVGEFRIDLSKFDDSSSSASQKVSVRAYSIGNTPATTSTNITSPTTSTGVVTDKGDTNEKGDTPTDVNASNDNDNLNTNIDGKYQDWKNMTLTEGYNGYTAMSSDGDNIYVYVKMKNGTVPGYGDYNFDIGGKKFYIWSDNISNNLSSGESKKISLTGGDINEGHQYGTVGTGYVSNVDNKSVAEFKIDMSKLGVSSMTGQTITMSNPNIGAQKVTVAGGSTGPILLSGIGAVVAILGYVQLKRKGYLDKKDLRISGK
>NZ_CP019323.1|WP_083686008.1|243881_244745_-|alpha/beta-hydrolase
MRLEWKKSDDHRDLGLPTNPKGVKRYNDISYGPVGVSNLLDVYEPNNTPGKLPVIVNCHGGGYFYGTKETYQFYGLDWAKRGFAFVNFNYRLAPETVFPGALQDTDKVMQWVSENAEEYNLDLNRVFLVGDSAGGNMVLQFMTAYSNTNYRDWFGFKELDKVNILGAAMNCGVYFLNRPGAISGAVESYFTAKVQKEMHEQMTPQNYIDATVPPLYVMSANQDFLHDEAVRMDQFLCDSNIKHEFKIYGDEDHPRGHVFHVNMRDDLARECNDDEQKFFEAEFDKVR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP019323_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019323_3

340849-340974

Orphan

Consensus_repeat	Method
CTTTGAGCTTGTAACCTTTCTACTCAAACTTGCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP019323_3

>merge|NZ_CP019323|3|340849-340974|CRISPRCasFinder
CTTTGAGCTTGTAACCTTTCTACTCAAACTTGCTGAAATGCGATTCAAATCTTGGTTTCTTCTCTATTGAATCTTTTTTAGGTCTTTGAGTGCTTTGAGCTTGTAACCTTTCTACTCAATCTTGCT

>NZ_CP019323|3|3|340849-340974|CRISPRCasFinder
CTTTGAGCTTGTAACCTTTCTACTCAAACTTGCT	GAAATGCGATTCAAATCTTGGTTTCTTCTCTATTGAATCTTTTTTAGGTCTTTGAGTG
CTTTGAGCTTGTAACCTTTCTACTCAATCTTGCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019323.1\|WP_076613846.1\|338591_339644_-\|D-alanine--D-alanine-ligase	unknown	unknown	gnl\|CDD\|234948
NZ_CP019323.1\|WP_076613840.1\|331361_331829_-\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|377139
NZ_CP019323.1\|WP_076613844.1\|335668_337099_-\|6-phospho-beta-galactosidase	unknown	unknown	gnl\|CDD\|184102
NZ_CP019323.1\|WP_076613849.1\|341842_342592_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|283645
NZ_CP019323.1\|WP_076613853.1\|346804_348301_+\|cardiolipin-synthase	unknown	unknown	gnl\|CDD\|211988
NZ_CP019323.1\|WP_076613851.1\|345417_345858_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076613841.1\|331897_332902_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380509
NZ_CP019323.1\|WP_083686011.1\|337487_338357_-\|PRD-domain-containing-protein	unknown	unknown	gnl\|CDD\|170086
NZ_CP019323.1\|WP_076613855.1\|350248_351202_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|369561
NZ_CP019323.1\|WP_076613847.1\|339820_340771_+\|DUF1002-domain-containing-protein	unknown	unknown	gnl\|CDD\|377628
NZ_CP019323.1\|WP_083685894.1\|351314_353423_-\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NZ_CP019323.1\|WP_076613845.1\|337131_337470_-\|PTS-lactose/cellobiose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|224364
NZ_CP019323.1\|WP_076613843.1\|333633_335415_-\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|273055
NZ_CP019323.1\|WP_076613857.1\|353557_353938_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|319924
NZ_CP019323.1\|WP_076613842.1\|333125_333578_+\|DUF3284-domain-containing-protein	unknown	unknown	gnl\|CDD\|378692
NZ_CP019323.1\|WP_083685892.1\|341098_341941_-\|viroplasmin-family-protein	unknown	unknown	gnl\|CDD\|260010
NZ_CP019323.1\|WP_076613852.1\|345864_346566_+\|zinc-metallopeptidase	unknown	unknown	gnl\|CDD\|377289
NZ_CP019323.1\|WP_083685893.1\|342742_345418_+\|YhgE/Pip-domain-containing-protein	unknown	unknown	gnl\|CDD\|224428
NZ_CP019323.1\|WP_076613839.1\|330555_331350_-\|PTS-sugar-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|377077
NZ_CP019323.1\|WP_076613854.1\|348487_349954_-\|catalase	unknown	unknown	gnl\|CDD\|163712

Protein	Function_ID	Function_description	E-value
NZ_CP019323.1\|WP_076613846.1\|338591_339644_-\|D-alanine--D-alanine-ligase	gnl\|CDD\|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	9.50931e-113
NZ_CP019323.1\|WP_076613840.1\|331361_331829_-\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|377139	pfam03830, PTSIIB_sorb, PTS system sorbose subfamily IIB component.	4.93813e-55
NZ_CP019323.1\|WP_076613844.1\|335668_337099_-\|6-phospho-beta-galactosidase	gnl\|CDD\|184102	PRK13511, PRK13511, 6-phospho-beta-galactosidase; Provisional.	0
NZ_CP019323.1\|WP_076613849.1\|341842_342592_+\|alpha/beta-hydrolase	gnl\|CDD\|283645	pfam06028, DUF915, Alpha/beta hydrolase of unknown function (DUF915). This family consists of several bacterial proteins of unknown function. Members of this family have an alpha/beta hydrolase fold.	2.87583e-42
NZ_CP019323.1\|WP_076613853.1\|346804_348301_+\|cardiolipin-synthase	gnl\|CDD\|211988	TIGR04265, bac_cardiolipin, cardiolipin synthase. This model is based on experimentally characterized bacterial cardiolipin synthases (cls) from E. coli, Staphylococcus aureus (two), and Bacillus pseudofirmus OF4. This model describes just one of several homologous but non-orthologous forms of cls. The cutoff score is set arbitrarily high to avoid false-positives. Note that there are two enzymatic activites called cardiolipin synthase. This model represents type 1, which does not rely on a CDP-linked donor, but instead does a reversible transfer of a phosphatidyl group from one phosphatidylglycerol molecule to another.	2.16565e-148
NZ_CP019323.1\|WP_076613841.1\|331897_332902_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|380509	cd06286, PBP1_CcpB-like, ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species. This group includes the ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species. Catabolite control protein B (CcpB) is 30% identical in sequence to CcpA which functions as the major transcriptional regulator of carbon catabolite repression/regulation (CCR), a process in which enzymes necessary for the metabolism of alternative sugars are inhibited in the presence of glucose. Like CcpA, the DNA-binding protein CcpB exerts its catabolite-repressing effect by a mechanism dependent on the presence of HPr(Ser-P), the small phosphocarrier proteins of the phosphoenolpyruvate-sugar phosphotransferase system, but with a less significant degree.	9.66093e-99
NZ_CP019323.1\|WP_083686011.1\|337487_338357_-\|PRD-domain-containing-protein	gnl\|CDD\|170086	PRK09772, PRK09772, transcriptional antiterminator BglG; Provisional.	5.39366e-27
NZ_CP019323.1\|WP_076613855.1\|350248_351202_+\|alpha/beta-hydrolase	gnl\|CDD\|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	2.32554e-86
NZ_CP019323.1\|WP_076613847.1\|339820_340771_+\|DUF1002-domain-containing-protein	gnl\|CDD\|377628	pfam06207, DUF1002, Protein of unknown function (DUF1002). This protein family has no known function. Its members are about 300 amino acids in length. It has so far been detected in Firmicute bacteria and some archaebacteria.	5.99347e-63
NZ_CP019323.1\|WP_083685894.1\|351314_353423_-\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	5.72717e-23
NZ_CP019323.1\|WP_076613845.1\|337131_337470_-\|PTS-lactose/cellobiose-transporter-subunit-IIA	gnl\|CDD\|224364	COG1447, CelC, Phosphotransferase system cellobiose-specific component IIA [Carbohydrate transport and metabolism].	3.61797e-37
NZ_CP019323.1\|WP_076613843.1\|333633_335415_-\|PTS-transporter-subunit-EIIC	gnl\|CDD\|273055	TIGR00394, lac_pts_IIC, phosphotransferase system, lactose specific, IIC component. This family of proteins models the IIC domain of the phosphotransferase system (PTS) for lactose. The IIC domain catalyzes the transfer of a phosphoryl group from the IIB domain to lactose. When the IIC component and IIB components are in the same polypeptide chain they are designated IIBC. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS].	3.15931e-156
NZ_CP019323.1\|WP_076613857.1\|353557_353938_-\|hypothetical-protein	gnl\|CDD\|319924	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.11556e-07
NZ_CP019323.1\|WP_076613842.1\|333125_333578_+\|DUF3284-domain-containing-protein	gnl\|CDD\|378692	pfam11687, DUF3284, Domain of unknown function (DUF3284). This family of proteins with unknown function appears to be restricted to Firmicutes.	0.00321646
NZ_CP019323.1\|WP_083685892.1\|341098_341941_-\|viroplasmin-family-protein	gnl\|CDD\|260010	cd09278, RNase_HI_prokaryote_like, RNase HI family found mainly in prokaryotes. Ribonuclease H (RNase H) is classified into two evolutionarily unrelated families, type 1 (prokaryotic RNase HI, eukaryotic RNase H1 and viral RNase H) and type 2 (prokaryotic RNase HII and HIII, and eukaryotic RNase H2). RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner. RNase H is involved in DNA replication, repair and transcription. RNase H is widely present in various organisms, including bacteria, archaea and eukaryotes and most prokaryotic and eukaryotic genomes contain multiple RNase H genes. Despite the lack of amino acid sequence homology, type 1 and type 2 RNase H share a main-chain fold and steric configurations of the four acidic active-site (DEDD), residues and have the same catalytic mechanism and functions in cells. One of the important functions of RNase H is to remove Okazaki fragments during DNA replication. Prokaryotic RNase H varies greatly in domain structures and substrate specificities. Prokaryotes and some single-cell eukaryotes do not require RNase H for viability.	8.39607e-56
NZ_CP019323.1\|WP_076613852.1\|345864_346566_+\|zinc-metallopeptidase	gnl\|CDD\|377289	pfam04298, Zn_peptidase_2, Putative neutral zinc metallopeptidase. Zinc metallopeptidase zinc binding regions have been predicted in some family members by a pattern match (Prosite:PS00142), of the characteristic HEXXH motif.	1.43645e-115
NZ_CP019323.1\|WP_083685893.1\|342742_345418_+\|YhgE/Pip-domain-containing-protein	gnl\|CDD\|224428	COG1511, COG1511, Predicted membrane protein [Function unknown].	4.8451e-111
NZ_CP019323.1\|WP_076613839.1\|330555_331350_-\|PTS-sugar-transporter-subunit-IIC	gnl\|CDD\|377077	pfam03609, EII-Sor, PTS system sorbose-specific iic component.	5.3514e-70
NZ_CP019323.1\|WP_076613854.1\|348487_349954_-\|catalase	gnl\|CDD\|163712	cd08156, catalase_clade_3, Clade 3 of the heme-binding enzyme catalase. Catalase is a ubiquitous enzyme found in both prokaryotes and eukaryotes, which is involved in the protection of cells from the toxic effects of peroxides. It catalyzes the conversion of hydrogen peroxide to water and molecular oxygen. Catalases also utilize hydrogen peroxide to oxidize various substrates such as alcohol or phenols. Clade 3 catalases are the most abundant subfamily and are found in all three kingdoms of life; they have a relatively small subunit size of 43 to 75 kDa, and bind a protoheme IX (heme b) group buried deep inside the structure. Clade 3 catalases also bind NADPH as a second redox-active cofactor. They form tetramers, and in eukaryotic cells, catalases are located in peroxisomes.	0

>NZ_CP019323.1|WP_076613847.1|339820_340771_+|DUF1002-domain-containing-protein
MKKLNIVLLSLVSLITFGIFTTQSVKADSLSDQPVMTLGTSLTDSQKQGTISALSSQISGSDSNYTTVTVTGDTLVKYLNPSGSSFTSSSGVWSSALIQKTSSGSGINVKIVDYNGTNNITTITADQYRNAAITAGISDANIYVTSATQIDGSGALAGIYAAYASTGNSLNQSQVNAAQNEMGVLSGITDANKGTDGYTDKQLNNAVAGMKSDIAQKGTNITVNQITTIVNNNLQRNDLQNIITDNQKQKIINLMVEIRDSGALKNSNFKKQASRLSSDITSKAKNLFNNLDTQENRNFIQKIWDSIVSFFQGLFN
>NZ_CP019323.1|WP_076613846.1|338591_339644_-|D-alanine--D-alanine-ligase
MKIVVLSGGRSTERNVSLSSGVKITNALRSKGYEVAYVDSFLGVDVEEERIDDLFTTQPEDEKNLVIADEVLTDEKINALRKDDTIGLLGKNVLKICQHADIVYMGLHGEDGENGKMQAVFDVFDIKYTGSGSLASGIAMDKKFSKEVFVQNHIQTADYTTTTTSDITADDIPFGFPMVVKPSNGGSSVGTHIIRNESELKDNIADALRFDKEVLIEEYIKGREFSVAMVDNHALPAVEITVDTGWYDFQHKFVENNVTHFITPPDLDDETHQRMQEMTKDTFEALGMSNYGRVDFLLRDSELYVMEANTLPGMTPLSLMPREAKAAGISYADLCESIIKSKVRIYENEK
>NZ_CP019323.1|WP_083686011.1|337487_338357_-|PRD-domain-containing-protein
MLLVVNRVYNNNTVLVDVDKNKQAIIQGRGVGFQRRRGDEVLPASVERIFYLDTDEARHRFGSLLKDVPIDITMTSFSIIEMAKKTYHYPLLDYIYVTLTDHISQTYKHLMAGKYEKSTVPDIRERYPTEYKIADKALQMINHDLNVHFPNDATKALALHFINARGTEQEDHPKEENPSTRVNEVVQSVFKEYGITRNITNQNYFDRLMIHLQYLVERLQTNEQDKRLLSQDIESDFQKLYPKSFEIANEITDKLQSSLHITLNDNELVYFIIHIQRLIQESETTSSNS
>NZ_CP019323.1|WP_076613845.1|337131_337470_-|PTS-lactose/cellobiose-transporter-subunit-IIA
MATKEEISMTGFSIVAYAGDAKTDLISALRKARDGDIEAAHKLVESANDSINDAHNEQTKLLSKEAGGEDMDVTFIMVHGQDTLMTTMMLKDEVEFFIDEYDRINKIEKKLG
>NZ_CP019323.1|WP_076613844.1|335668_337099_-|6-phospho-beta-galactosidase
MDIELNRVKKLPKGFVWGGATAAYQVEGSTKVDGKGKTMWDDYLKKQGRFSPDPASDFYNRYPEDISLSKKYGLNAIRVSISWTRIFPEGFGKPVQAGVDYYHRLFKECIDQGITPYVSLHHFDSPKTLFDDGDWLNRKNIDYFVEYAKFCFDEFTEIKHWFTINELISLAYSQYIQGNFPPNHKFDVTSAIQAEHNELLAHARVVNLFKDGGYDGKIGLIHVLQPVYPYPEKKENQHAADLQDAFMNAFLLDGTFKGEYSDKTMKLINEILTANDAKLDIQDGDMDILKKASTQNDYFGLNYYQPSFVAAYAGDSTNHFNGTGEKGTSSFKFKGVGQAVKNPNIPTTDWDWNIYPEGLYDILKRVSTDYPESKEIFITENGLGLKEELPEDVKDDTIIEDDKRIDFVDQHMEAILRARDEGVNVNGYFIWSLQDQFSWANGYNKRYGLFFIDFATQKRYIKKSALWYKALADTMK
>NZ_CP019323.1|WP_076613843.1|333633_335415_-|PTS-transporter-subunit-EIIC
MQFIIDKLEKHQKFFDKISKNIYLMAIKDGFLAAMPIILFSSVFIMLTNIPPLFHVNLPVGLNDWFNKIYNYTMGFVGFYVAGTTARALTGSMNQRIKGSRFINATSTQMASMAGFMMLAISQTKSGAFVGDYFGTKGILSAFVSAFITVLVYKFCVEKDITIKMPKEVPGTISQVFRDVFPFSFSIIIMGLLDVGVRAWLNVPFSEMIATLIAPIFKGAESYVGMAFIWFLIPLFWFMGIHGPSIVKPAITAALYGNTTANLDLFKAGNFPFHSLTENFGNFVGELGGTGATFVVPFIFMFLMKSKQLKAIGKASFIPVMFAVNEPLLFGAPIILNPYFFIPFVLAPVVNVVIGKFFIDVLGMRGFMYILSWAIPGPIGAFFDTNFQPISLVLMVLLLVLDTLIYLPFCRAYDATLVKEEAENLEKEEAEDTDGVALAGSSTGSSTTATPEVATEDTDSNDKVSDPSDITKLDHQIRVLVLCAGGGTSEQLANALTDGAKKYNVPIIASAGAYGSHRDILPNFDLVVLAPQVRIYYDDLKADTDRLGIQLVATKGQQYIALTRDSKKALDFVMENLKKNNEETTSDPATSND
>NZ_CP019323.1|WP_076613842.1|333125_333578_+|DUF3284-domain-containing-protein
MKYTYKMKASQEAVYQALMREQLHYFQQFIPGLKKLRPRVEINKKLQTKQSKKSVDTTIKVSEIKQPELYIQEADSSNGHIVQTFNIVKTGETCELVYSEDMYTIKGGAKRSYGLLTPLYKYSFNSACKKRGIYLDKVALERFTKSESKI
>NZ_CP019323.1|WP_076613841.1|331897_332902_-|LacI-family-DNA-binding-transcriptional-regulator
MATISDVARLAGLSVSTVSRVINDSPHVSPKKRKLVKEAMNQLGYVPLPAARQLRGSSSKSLAVVVPRIVNPFFSHLIDAIERTLVSAEFNTIIVQTYGSKKQELNALELLKMQQVDGVILCSLENEWSVISEYLKFGKIVLANEYLKDLPIPMIYADQYQGLKSGTEYLIKQGFKNIAYATGRKTLSIAPLGSDFDSDRFHGFQDALQDADMSYNSNLIFYNAHTEEDGNNILDSILQLEDKPDAIIAGSDEVAAGIVEEARSRGVLVPSQLGILGIDDQPMSSKLNIPLSTIRQPVDEMGIKAAQVMISELDGNKERNIELLKLEVIPRQSA
>NZ_CP019323.1|WP_076613840.1|331361_331829_-|PTS-sugar-transporter-subunit-IIB
MTVVLARIDQRLVHGLIVNQWAQALKVKRFMVVDDEISQNEDIKASMRMSKPAGTGMSIINTEKAITNFTSGKYDAQRVFVLVKEPETLIKLIDAGVEIPKVDLGIIFNEDGRVPVTKFVALNDKEKSDLKTIQDKNIPTVIQYVPTDTEEPYKG
>NZ_CP019323.1|WP_076613839.1|330555_331350_-|PTS-sugar-transporter-subunit-IIC
MSGIQLLQDILIIILAGYMTIDQNGLVIMSWFPVIVGTIAGIIMGDLTTALTIAGTFQLMMLGVAALGGASAPNYGLATIIGVFIATRTGTGIKSAIAVGLPVGLLAIQLEVVARIIANFLAHKMQSDNNNSQWKKMNLEAWLGPILFSLQTALPAILIVFFGPEVVTFILKVVPTWVTDGLTVAGGMLPVVGIGMLLHYMPVKKFLPYIIVGFVLAAYLNVGVLGIALIGFAGAYWYFFSESKKVSEPVTGATSDDEDDDYDE
>NZ_CP019323.1|WP_083685892.1|341098_341941_-|viroplasmin-family-protein
MIKLQCRLNHFFSRVVPTTKAVNIKYRPLFIFHCFTPANLLYNEKYKIITRRGKTVQKYYAVRRGKNPGIYRSWAECKSQVDGFTGARYKSFTTEAEAKEFLKGKDSYTPKTKTNKSSDIKDFDIVIYTDGGSRNHGNVKGGHVKSNDRAAWAYHINAGSKVFEGTDGEFGATNNRMEIMALIESIKRLNELKLNNRKIIFILDSQYVLNAITKNWLNGWKRRGFKKADGKVPINVELWKELDKLLPTVSDKTFEWTKGHATNVGNNRVDELLNETMDKM
>NZ_CP019323.1|WP_076613849.1|341842_342592_+|alpha/beta-hydrolase
MENKQWPIFYIHGFRGGDYTTEKMIESALKFNHKDEYLKATISWRGKITYEGTWTSDHHPIIQVVFKNKYVGSTQISYWLSKLLFNLRTKHEFDTYDAIGHSLGAVALLLVNLKEKLHPYMPRLKKLVTIAGPFNGILGLGDLPNVNRIKPDGRPAFMSPTYFRIFMGRNSISDDLRVLNIYGNVDDHSNSDKYISVTSVKSISYILKPRVKEYIDYPVNGSKAEHSLMHDNSEILKRVNNFIYSNPLT
>NZ_CP019323.1|WP_083685893.1|342742_345418_+|YhgE/Pip-domain-containing-protein
MLALIILPCLYCWFNVWALWDPYSNTSDLKVAVYSDDQSVKLNDEKIAIGKDLIANLKKNDGLGWTFVDSKQELNQGVKDGSYYAGIYIPKNFSKDIISFASGKIKKPTLVYSVNQKINAVAPKLTSSGATTLQNTISEEFIGTVSKTITNVLNKSGVEIENNLPMLRRLSSLLVTTDDNRDELQDIMDKVKQANTIVPDLNNKLSEANEMYGYIPQLNTDAQKLVTLNNFLPLADSGGTAVKQLQNKIPEIQSAGTQINTVDTDFSQISNLMDSSITQVNNGINVITSVENVMPEVTEFGKSAQSSVEDVNNNLIPKLQKALPVIKSTVDTGLSMVYNLSKQISTSATNINTLIDKIKENPDNDQVQSQLKTVLQNIADNGAQIGSVAKQVASTLTDLQNTYNQLASQNGKEQTTKLDRPIKLLNNLEPLGNTLATQANYILDNYDNLSTDELQSKLTELATQSNTLADQVTSIQNLGIIDSVSDTISTTQSLLTSASTVLSDLNTSVIPEIPALLNNTKGILQTAQTYLQKYQQQLPAIGNEIHDANTLLNGNMSNIVTGINVANDFYNNDYPNLKKKLATATFFVQYQLPEIENQLSTTLNLINTKTPELEQSLAAANDFAVNDWPQLEKDVHHSAKLLKAGTKDVDLSAIIKLMKADANTESDFFSNPVKLKQDNLYNIPNYGSASAPFYLALCIWVGALLLSSVFTVHFKLNDKEKLRYGFKQQFNGRYLTFFSLNLFQSIAASLGNIFILHAYVQNKVALVLFAMLISFVFISILYSLVQMFGTVGKGLGIIILVLSISGAGGNFPVVLSDGFFRVINPYLPFTYAVNLFREAVGGIYWPNAIKDIVVLLAFGIVFYLMGLLLTEKLKPLINKLHKSAKKSMIIE
>NZ_CP019323.1|WP_076613851.1|345417_345858_+|hypothetical-protein
MTKLKSYRPFITKNFLWEFPTHFKLKEASEFLGDSIAETTDYISNTAKNIMRNNSIYWFLQDKRTKELVGLIAVENIDQDKKSGKLVVQLSVTDSIDKEEIADRLVTFVKEQIDLDTLEFEALDHIVQEKFTNNGYNISSKELKRS
>NZ_CP019323.1|WP_076613852.1|345864_346566_+|zinc-metallopeptidase
MYGYLGYGFGPTFILVIIGIAISLWASWYVKHTFNRYDQYDSSRGTTGADAARYILDQSGLQNIQINRVSGNLTDNYNPGNKTLNLSDSTFASTSVAAIGVAAHECGHAIQDKNAYVPMRARAALVPAVNLGSNFSIPLIFVGILLGRNHTLIMAGIILFSLVVLFQLVTLPVEFNASGRAIKILSSGDLLEKNEVPMVRKVLGAAALTYVAAALSSALQLIRLILIFGNNRD
>NZ_CP019323.1|WP_076613853.1|346804_348301_+|cardiolipin-synthase
MIDVWIIWLILIILLLNTISALITVFHRPRNIVTTWAWILVLILLPIVGFLIYAFFGRGIAQEKIFSISNQKHVGLDQLKLMEIADTTKRRLIENQNNNNDPATRSDQTHYADHIIKFFNETEEAPLTRHNKVDLFFDGKEKFEKMFEDVRNAKETVHVEYYAFIKSDIGDEFLKLLTQKAKEGLEVRLIYDPWGSNGTRKSWFKDFEAAGGEVLQFITSKNVIAKTRLNYHLHRKIVVIDGCIGWTGGFNVGDQYVNVTEKFGYWRDTHVRIKGVATLLLQERFFQDWNASIEKSEEALVFDEKYFPSDKFDDTDNSPIQIVSDGPDRREEVLKDGFIDMIVSAKKSVWIQSPYLVPDDPMFTALTIAARSGVDVRIMIPCMPDHPFIYRATQYYANLLTSYGIKIYSYQKGFLHAKASVFDGKICTVGSMNQDFRSYSLNFEANAFIYDSKVAHKISRAFENDMKDSLLITPEVIKSQGHWLHFKQRFSRLLSPIL
>NZ_CP019323.1|WP_076613854.1|348487_349954_-|catalase
MTKKLTTEAGQPFADNQHTQTAGSRGPVLIQDYDMLEKIAHFDRERIPERVVHAKGAGATGVFELENDMGKYTKADLFSGAGKKTPIMMRISQVAGEKGYPDTVRDVRGFSIKFYTQEGNYDIVGNNTPVFFVNDPLKFPDFIHSQKRDPKTNRRTQDMQWDFWSHSPESLHQVTYLMGDRGLPASYRTMNGYGSHTFKWVNKDGEQFWIKYHMMSNQGVKNISAQLADKLASENTDYLQDDLFDAIDKGDFPSWNMYVQIIPYEEGLKYKWDIFDVTKVVSHKDYPLIKVGKLTLNKNPENYFTDVEEAAVSPANFVPGIEPSPDKLLQGRLFAYKDTQRYRLGANFEDLPVNRPLVEVHNYERDGAMKSDNQGSGVNYEPNSFDGPKEVPNAAIKHYEVEGMAGNQAYSHNVDYTTQPGDLYRLMSDEEKDRLIETIKDNLGQVKKDEIKILEIKQFYGADKDYGTRVAKALNMDIDEIMNSENFV
>NZ_CP019323.1|WP_076613855.1|350248_351202_+|alpha/beta-hydrolase
MINRISLESEALAICEGTDPHPRIYEGSADDGRKILNDLQNSPVTKSNVDIQDVAVDTGEWGQINVRIIRPEANYGKLPVIFYIHGAGWVFGNAHTHDKLVRELALRTNSVVVFPEYSLSPEAKYPTAIEQNYAALKWVEKNAKDINVDIDKLTVAGDSVGGNMATVMTLMAKERKGPQIKQQLLYYPVTNANFDTESYNTFADHYYLTKEGMEWFWDQYTTDPEQRAEITASPLRATKEQLEGLPDAMILNGEADVLRDEGEEYARHLREAGVDVTQIQFQGMIHDFVMINSLDEAKATRAAMDASTKWLNKKNNK
>NZ_CP019323.1|WP_083685894.1|351314_353423_-|BspA-family-leucine-rich-repeat-surface-protein
MAQNSTYEISIKFRKTILTGIIAMGGLCLFVCRGVTVHASKNDSEIQRLMDVNAILESEATSSDAVSVIQPKDDSLMSGVFGTCDWDVDSDGTLTIHEGTLDAGAGNWMSYVDYIVNVKIDDGVIFNQDSSNLFASLTNVKTIDVTNADTSNVYDMSNMFKSCPVLTTISGIKNFDTSQTTNMHGMFDTVVSLKTLDLSTWDTSNVVDMGRLFAGDSALKVTGLNDLDTSQVTDMQYMFYNSRQESLDDIENWDVSKVENFAWFFGSCTKLTEIDLSNWDTSSATSMQSMFTQMSAYPVINMGGKFTTENVTNFSLMFASSNMETLDLSNFNTSKVLNMSWMFSNTKYLTTLLGSFDTSSTTSLDTMFSNSSLNDLSGLNLEEWDTSKCTNFSNMFTNTTFTNLDVVANFDFSKAFIISEMFSGCKNLTSIDVSKFDLSKVSSASSIFEGDTSLRTLDLSSWDTTNLDMGDALSGTDSLWKINLGPKTILSSNIGLVTPPGNDTEIFDDTTSEVYTNISDHWQTVLNGTDHDPKGPTYSVDDIYNLYANPSSSDSTIVWQQEPYYEASIEVPSVDFKASLPSAKGVVQRQSDWGIIFHNYSYPAQPLTKSIEVKVSSPLTSTEGNVLNDSLIFKKENGETVTLNDNNQSIFNGSIPSTIGDDGSGNQQLLWDDDGGLLLNLDGTQLSGDYQGTLDWTMVDSV
>NZ_CP019323.1|WP_076613857.1|353557_353938_-|hypothetical-protein
MLQKLEVMLYVRNVDLIARFFEDALGATLIKETEMIDTSTEIKLSVLDQVNINLYDVEFIREYSPMVSLEMPSLMFLTNDIREVHDRIEMFANTISEISTQGDQLVFNFSDPEDHHFAVGTIEQDI

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP019323_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019323_4

497844-497963

Orphan

Consensus_repeat	Method
CGAAAACGTGTGACAAAACACAATTTTCTCAATATAAGCCCAAAAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP019323_4

>merge|NZ_CP019323|4|497844-497963|CRISPRCasFinder
GGAAAACGTGTGACAAAATTCCACTTTTTTCACAGAATTCGCTAAGCGCTTGTGACACATAAATGGTTTTCTTACGAAAACGTGTGACAAAACACAATTTTCTCAATATAAGCCCAAAAG

>NZ_CP019323|4|4|497844-497963|CRISPRCasFinder
GGAAAACGTGTGACAAAATTCCACTTTTTTCACAGAATTCGCTAAG	CGCTTGTGACACATAAATGGTTTTCTTA
CGAAAACGTGTGACAAAACACAATTTTCTCAATATAAGCCCAAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019323.1\|WP_076613980.1\|501958_503350_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|182694
NZ_CP019323.1\|WP_076613974.1\|495205_495394_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076613972.1\|493246_493672_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NZ_CP019323.1\|WP_076613968.1\|488857_489589_+\|acetylglutamate-kinase	unknown	unknown	gnl\|CDD\|234869
NZ_CP019323.1\|WP_076613975.1\|495632_495956_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP019323.1\|WP_076613982.1\|504492_505053_-\|DUF1211-domain-containing-protein	unknown	unknown	gnl\|CDD\|226078
NZ_CP019323.1\|WP_076613981.1\|503414_504353_+\|AEC-family-transporter	unknown	unknown	gnl\|CDD\|223751
NZ_CP019323.1\|WP_076613978.1\|499220_500156_-\|NADP-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|176191
NZ_CP019323.1\|WP_076613970.1\|490913_492053_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|181076
NZ_CP019323.1\|WP_076613977.1\|498116_499121_-\|SLAP-domain-containing-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076613971.1\|492074_492983_-\|cysteine-synthase-family-protein	unknown	unknown	gnl\|CDD\|107204
NZ_CP019323.1\|WP_076613979.1\|500354_501779_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|182694
NZ_CP019323.1\|WP_076613973.1\|493793_495179_+\|DHA2-family-efflux-MFS-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|129794
NZ_CP019323.1\|WP_083685902.1\|505934_506642_-\|cation:proton-antiporter	unknown	unknown	gnl\|CDD\|223104
NZ_CP019323.1\|WP_076613984.1\|508058_509474_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|129987
NZ_CP019323.1\|WP_076613969.1\|489620_490751_+\|acetylornithine-transaminase	unknown	unknown	gnl\|CDD\|179505
NZ_CP019323.1\|WP_125673059.1\|505064_505874_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223104
NZ_CP019323.1\|WP_076613976.1\|496152_497625_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341045
NZ_CP019323.1\|WP_076613983.1\|506753_507920_-\|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl\|CDD\|224090
NZ_CP019323.1\|WP_076613967.1\|487612_488827_+\|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ	unknown	unknown	gnl\|CDD\|239065

Protein	Function_ID	Function_description	E-value
NZ_CP019323.1\|WP_076613980.1\|501958_503350_+\|amino-acid-permease	gnl\|CDD\|182694	PRK10746, PRK10746, putative transport protein YifK; Provisional.	0
NZ_CP019323.1\|WP_076613984.1\|508058_509474_+\|amino-acid-permease	gnl\|CDD\|129987	TIGR00909, putative_amino_acid_transporter, amino acid transporter. [Transport and binding proteins, Amino acids, peptides and amines].	3.41054e-118
NZ_CP019323.1\|WP_076613981.1\|503414_504353_+\|AEC-family-transporter	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	1.96322e-34
NZ_CP019323.1\|WP_076613972.1\|493246_493672_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	2.15241e-09
NZ_CP019323.1\|WP_076613968.1\|488857_489589_+\|acetylglutamate-kinase	gnl\|CDD\|234869	PRK00942, PRK00942, acetylglutamate kinase; Provisional.	1.82319e-82
NZ_CP019323.1\|WP_076613975.1\|495632_495956_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	8.18483e-09
NZ_CP019323.1\|WP_076613982.1\|504492_505053_-\|DUF1211-domain-containing-protein	gnl\|CDD\|226078	COG3548, COG3548, Predicted integral membrane protein [Function unknown].	7.22873e-31
NZ_CP019323.1\|WP_076613969.1\|489620_490751_+\|acetylornithine-transaminase	gnl\|CDD\|179505	PRK02936, argD, acetylornithine transaminase.	0
NZ_CP019323.1\|WP_076613978.1\|499220_500156_-\|NADP-dependent-oxidoreductase	gnl\|CDD\|176191	cd05289, MDR_like_2, alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases. Members identified as zinc-dependent alcohol dehydrogenases and quinone oxidoreductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	3.14793e-140
NZ_CP019323.1\|WP_076613970.1\|490913_492053_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|181076	PRK07671, PRK07671, bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase.	0
NZ_CP019323.1\|WP_076613971.1\|492074_492983_-\|cysteine-synthase-family-protein	gnl\|CDD\|107204	cd01561, CBS_like, CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. Deficiency of CBS leads to homocystinuria, an inherited disease of sulfur metabolism characterized by increased levels of the toxic metabolite homocysteine. Cysteine synthase on the other hand catalyzes the last step of cysteine biosynthesis. This subgroup also includes an O-Phosphoserine sulfhydrylase found in hyperthermophilic archaea which produces L-cysteine from sulfide and the more thermostable O-phospho-L-serine.	5.27525e-136
NZ_CP019323.1\|WP_076613979.1\|500354_501779_+\|amino-acid-permease	gnl\|CDD\|182694	PRK10746, PRK10746, putative transport protein YifK; Provisional.	0
NZ_CP019323.1\|WP_083685902.1\|505934_506642_-\|cation:proton-antiporter	gnl\|CDD\|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	1.79681e-18
NZ_CP019323.1\|WP_076613973.1\|493793_495179_+\|DHA2-family-efflux-MFS-transporter-permease-subunit	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.06667e-63
NZ_CP019323.1\|WP_125673059.1\|505064_505874_-\|hypothetical-protein	gnl\|CDD\|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	6.46147e-06
NZ_CP019323.1\|WP_076613976.1\|496152_497625_-\|MFS-transporter	gnl\|CDD\|341045	cd17502, MFS_Azr1_MDR_like, Saccharomyces cerevisiae Azole resistance protein 1 (Azr1p), and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of multidrug resistance (MDR) transporters including various Saccharomyces cerevisiae proteins such as azole resistance protein 1 (Azr1p), vacuolar basic amino acid transporter 1 (Vba1p), vacuolar basic amino acid transporter 5 (Vba5p), and Sge1p (also known as Nor1p, 10-N-nonyl acridine orange resistance protein, and crystal violet resistance protein). MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. This subfamily belongs to the Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters (MMR-like MDR transporter) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.57207e-44
NZ_CP019323.1\|WP_076613983.1\|506753_507920_-\|pyridoxal-phosphate-dependent-aminotransferase	gnl\|CDD\|224090	COG1168, MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism].	1.44504e-149
NZ_CP019323.1\|WP_076613967.1\|487612_488827_+\|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ	gnl\|CDD\|239065	cd02152, OAT, Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in the arginine biosynthetic pathway. Members of this family may experience feedback inhibition by L-arginine. The active enzyme is a heterotetramer of two alpha and two beta chains, where the alpha and beta chains are the result of autocatalytic cleavage. OATs found in the clavulanic acid biosynthesis gene cluster catalyze the fifth step only, and may utilize acetyl acceptors other than glutamate.	0

>NZ_CP019323.1|WP_076613976.1|496152_497625_-|MFS-transporter
MSRNRKILVTFALVLSNMMAGLDATIINTALPAIISDLHGIQYMGWIVAIFLLGMAVSTPLWSKFGEKKGNKVAYITATIVFMIGALFQGLAPNIIWFITARSIMGIGAGGMNTIPFIIYSQIFKNIKRRSQVIGIASAGFSGTSIVGPLIGGWIVDSFSWHWVFYINLPLALLSITIVSIYFNIKEKLNEEKVDYFGAVLMVLGLTSFLIGIQLLGVSSIWITLVFIILGAGLIFWMSRVEEKVEDPIVPNRLFKNEKLVIDLILFALLWGSFVAFNIYIPMWAQGIMGLTALIGGMTQIPGAIANFIGSELEPFMQRRMSRYVIIAIGTLSFLISFAGLFWASQNASYTFLLIMGVFEGFGVGICFNALLIAVQFDVEQRDVPISTSFAYLVRILSQTFMSSIYGVILNLALIKGVRGSHGHITMSMMNKLSNAAVAKELPKAVVPEMKRIFFSGIHNIMLSALILIILVIIILVYLFSSEAHKKSAI
>NZ_CP019323.1|WP_076613975.1|495632_495956_+|helix-turn-helix-transcriptional-regulator
MINEIGKIIRDKRRSLSLTIEQLAEKADVSESLVSQLERGVNSNISINKLERISTAVDLKLPDLFDKPANNGIKYLELLDFLADLPRDKREDISDKILALLSSMHTL
>NZ_CP019323.1|WP_076613974.1|495205_495394_-|hypothetical-protein
MLQIKLVPYHEEAEESERQYIFTENLNMTIERLEKSDNKVIDVDFFNTTDTSYAAIKYEAKK
>NZ_CP019323.1|WP_076613973.1|493793_495179_+|DHA2-family-efflux-MFS-transporter-permease-subunit
MNRQLNSKLIISIIATGLLSFCGVVVETATNITFPVLMKEFSVSTSTVQWMTTGYLLVASIMMPLSAFLKNSFTSKKLFSTASILFILGLLLDVTAPTFIQLVTGRIIQGIGAGIALPLMFNIILEQAPINKIGFLMGLGTLVTAVAPAIGPTFGGLVVDTFNWRSIFLFLLPIVILALILGLVSIQQVTKPKRTKLDFIGLIYIALTFVGIIVGFSNLSTIVTSPMNFFIPFVIGVISLFLFLRHSVKSDNPLLNLNVFSNKSFSLHLGAYFLIQLIALGISFILPNYIQLVNNKSALIAGLIVLPGAAIGAILAPLSGTIYDKLGARKPIMTGIILEIISLLLFFILGKTLTITTILVIYIILMLGMGSVMGNTMTNALQQLNETQIADGNGMFNTVQQFAGAVGTSIVSTIIAFSQNSNSSLTYSAKTAIGAQHAFLLLLIFILIACLSLNHATKNSK
>NZ_CP019323.1|WP_076613972.1|493246_493672_-|MarR-family-transcriptional-regulator
MDRLFGILIKKANNAVNRDAEKYAQTLGLTSVQISIIDYVSHEENNQDIFQKDVEKEFNIRRATATSSLKLMEDRDLLVRVPVKSDARLKRIILTPKAHSLAKQIDDYFNETERRIINVMGSENKDIVRTALQHCIKELSD
>NZ_CP019323.1|WP_076613971.1|492074_492983_-|cysteine-synthase-family-protein
MLVDNIYQTIGNTPLMKLDIKVPNGSNIYAKLEMFNPGGSIKDRLGVNLIEDGIEKGLIKDKTTIIEPTAGNTGIGVALAAQKYHLTVKLVVPDQFSQEKQVLMKALGAELINTPAEDGIVGAIKKARDLASQIDDSYVPMQFVNEANPQTYYKTMGQEILHDIPTKIDAFVAGAGSGGTFVGTAKALLEKNREMKSITVEPAGSILNGGPKHSHRTEGIGVEFVPPFFKEIKVDDIQTIDDDDAFYYVRWMAKNLGLFAGSSSGAALAASLEVARTLPSNSTIVTVFPDSSERYLSKHIYN
>NZ_CP019323.1|WP_076613970.1|490913_492053_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MKFNTKLIHGGFSEDPTTGAVSTPIYRSSTFHQHKLGAGPKWEYGRTGNPTRASLETLIAEIEDGKYGFAFASGSAAIHAVFSTFSSGDHIVVGNDVYGGTFRLINKVLKRFGLEFTSVDTSDFDAVEKAIQKNTKAIYLESPTNPLLKITDIKGIAKIAKKHNLETIVDNTFATPYNQNPLTLGADIVVHSATKYLGGHSDVVAGLAVTSDDKIAEDLAFLQNSIGSVLGPDDSWLLMRGIKTLGVRMRVHDENTRIVYDYLNNNDKVARIYYPGNKESKGYEIAKEQMNTFGAMISFELQPGLDPKKFVESLKLIDLAESLGGIESLIEVPSVMTHAAIPREIRLQNGIKDELVRLSVGIEDSKDLLDDLKQAFDQI
>NZ_CP019323.1|WP_076613969.1|489620_490751_+|acetylornithine-transaminase
MEHVFPTYSRFPFDLVNGHDVYLDDNHGKTYLDFTSGIGVCSFGYSNEIIQQSVEEQIKKVWHISNLYESELQDKVADQLCNDDQLAFFCNSGTEANEAAFKLARKASGKSTVIAFNNGFHGRTYGSMSLTGNPDIRRGFEPLVPDIIFADYNDDAAINLINSDVAAVILEVIQGEGGVNNGNKSWLQGIQKACHDNGVILIIDEVQTGIGRTGTKFAFEQFNLDPDIITSAKALGNGTPIGAMIGKKKFAKFFGPGTHGTTFGGNKISLAAATGVLQQLTPEFLDGVQNKSKTVWDYLNNEIAPLNSVTDISGLGLMIGIHIDDKFPVGDVISQLQDAGLLTLSAKYNTLRLLPPLVMSEEELLNGLEKIKLVLK
>NZ_CP019323.1|WP_076613968.1|488857_489589_+|acetylglutamate-kinase
MEGTIVIKIGGNASNQLPDTFFQQIKNWWDMGKHVLIIHGGGPQISKWSEMLNLSVKKIDGIRVTDDATLDVTKAVLLGMVQPKICQYLSESGLPVIGMNASDNHLITGEYLNKSEYGEVGKVTGINKQWLDEVLEDQIGVLAPLAQTSDGQWLNVNADMAAAKIAVELNAESLVLITDVPGVLNSGKVVSQLTETDADDLFKKDIIKSGMMPKINASFAAHKNGVDQTFITNDLSKPGTHFQ
>NZ_CP019323.1|WP_076613967.1|487612_488827_+|bifunctional-glutamate-N-acetyltransferase/amino-acid-acetyltransferase-ArgJ
MQTSLENTSEYQIIEFTWPKGYQSDGLHAGLRKVKNDMGWIYSTTPAKAAGTYTTNQFQAAPTTLTKNTINKNHTLQAIIMNSAVANSCTGKLGEKNALTTQKLVAEKLNINPDLVGVASTGLIGDQLPMDIITKGIEKLQLTDNTEVTNAVLTTDKHAKTISIQIDIDGKPVTISGFCKGSGMIHPMMATMLGFVTTDANIEDGLLQEILSSEVDSTFNQITVDGDTSTNDMVVTMANGQAENTELTKDSPDYPSFVSAFHEVLSTLAQDIAEDGEGSTKLVEVNVQNAATHDDGQKVAKAIVGSNLVKSAIFGEDANWGRIVAAIGQTDATVDIEHTSIWLNDLPLVVDSQAADFDEKEMKQALSNNKITILVDLNSGTSTGQAWGCDLTYNYVRINATYKS
>NZ_CP019323.1|WP_076613977.1|498116_499121_-|SLAP-domain-containing-protein
MRRSIILSGILFSSLIFGATTTPAVVNAAEEVTAAATKDADTDVTANISYYDATNNLVGTETLTGAVGSTQTLNSIPAGYALQNAGNKTITLVNANGAKSYEQSVFVNKVVSNNIIFKTADESEVGRTTVSSEKVGDKVDLTDEQIPSGYAASDKSVTIQTDGNTQIVTVTKVDPISSFKGVVTTGKDNVSLYQVDGSAIKSRALAPNSAWSVDKKLVLNGVTYYRVATSEWAKGSDVTVEGDSTSTDTNTDTNTDTDTNTDATLPDGIVKADKTAVTTISEGSTTLYKADGTAIKNRGLGGKTSWLTTKMATINGEKMYKVATNEWVAAKDIK
>NZ_CP019323.1|WP_076613978.1|499220_500156_-|NADP-dependent-oxidoreductase
MKAVVINEYGNVDKLQMENITIPEIADDEVLVEVKATSVNPIDWKLREGYLAESIPLKFPIILGWDVAGVITRTGRKVKEFKTGDKVLARPDLTNRGTYAEYTAVKEDKLALLPENVSYEEAAALPLAGMTAWQGVYDYLEVKPGQKVLMQGGAGGVGIIAIQLLKHIGAHVYTTASAKNEEFLKSLGAERVIDYHDTDFSKELNDLDAVFDTVGGDTLAKSYSVLKQGGRLITIAGNIDEDLAKAKDITAQSIWLRPNGKQLTQLVNLVSEGVVKVIIDSTHPFTQDGVKAAQEVSESHHAKGKIVISMK
>NZ_CP019323.1|WP_076613979.1|500354_501779_+|amino-acid-permease
MEKKTLSRSLSSRQMQMIALGGTIGVGLFMGSASTIKWTGPSVLLAYALAGLILYMVMRALGEMLYVDPSTGSFAKYATEYIHPVVGYLTAWSNVFQYLVVGISEVIAVGTYLEFWWPSMPKWIAGVVVVVTLCVANLTSVKAYGELEFWFALIKVVTIIFMIILGLLVIIFGVGNHGHPVGISNLWVNGGFFTGGLKGFVFALSIVVASYQGVEVIGITAGEAEDPQNNIVRAIRSIVGRILIFYIGAIFVIVSIYPWDKLGTIGSPFVETFAKVGITFAAEIINFVMLTAAMSGCNSGIFSSSRMLYTLGLEKYLPKSFTKLSPHKVPYIPVITISAGILIGLILNYTLPVLFHTSSNIFVIVYSSSVLPGMVPWFVILISELRFRKQNAEHMKNHPFKMPLYPISNYLSIVALLIILVFMFMNPETTVSLMVGVVFLIVMTAIYFLHERGRDHTQTNATSTDEAFAEEDEK
>NZ_CP019323.1|WP_076613980.1|501958_503350_+|amino-acid-permease
MKEEKLKRSLSSRQMQMIALGGTIGVGLFMGSASTIKWTGPSVLLAYALAGLILYMVMRALGEMLYVDPSTGSFAKFGTEYIHPVVGYLTAWSNVFQWLVVGISEVIAVGTYLSFWWPNAPQWIVGVIVVVTLCIANLTSVKAYGELEFWFSLIKVVTIIFMIVLGFLVILFGVGNHGHPVGFSNLWANGGFFTGGLKGFIFALSIVVASYQGIEVIGITAGEAENPKETITHAIRSIVGRILIFYIGAIFVIVTIYPWNKLGTMGSPFTETFAKFGITFAAEIINFVVLTAALSGCNSGIFSSSRMLYTLGIENRLPKAFTKLSRHKVPYLPVIVISTGILIGLILNYALPLIFHTSNNIFVIVYSSSILPGMVPWFVILFSELRFRKQNAEQMVDHPFKMPFYPLSNYLSIAALVVILFFMFLNPETTVSLLVGVVFLVVMTLIYFIREHRIDKNDNVRKD
>NZ_CP019323.1|WP_076613981.1|503414_504353_+|AEC-family-transporter
MGVFFQSVQGILIIIILIAVGYVLAQKKWFSDESTKMIAKLVTQVALPAYMIYTITHDFTAAKLIKLLPNLVIPCLSMTILIGISVIMIKVLHIDKDHQGLFSSMFFNSNTVFVGLPVNMALFGPESLPYVLVYYMANTTFFWTLGTYLIQVDGEKKGTFNWKTTIGKLLSPPLLGFIIGLILVILHIQLPNFLMSDFQYVGNLTIPLSMIFIGISISNAGLTNVTFHKENVGVLFGRFICAPLLMSALFLFIPGPALMKQVFIIQAAMPVMTNAPVVAKLYHADSNYAAIMVTETTVLSLFVVPVLMMIIK
>NZ_CP019323.1|WP_076613982.1|504492_505053_-|DUF1211-domain-containing-protein
MKKERFEAFTDAVLAIILTILTLELRLPEDNHSINALISVVPQFVTYIFTFLSISTMWINHHYLFVHVKEIDNRILWYNIILLFWVSLLPATTAWVGSDILARVPAILYAVNILLYNMSFAFLRNSVTKKVADTKSGKIINRTKNLEWISFFINFISLLITFFIPPFVFVGITINMILWSISNFKN
>NZ_CP019323.1|WP_125673059.1|505064_505874_-|hypothetical-protein
MSRSRFSIPRYLSFFNQTVSFVGGVLNSYVFVVLGISIARIVTDQRVELSTTLKWLWIGITIYVVSTTIRYLYARFLSKNSKIEAVTFAFGGVHGAVTLALSFSLSEMGIKGTDFDLILLTETVVIILSMLVPTILFKFILNPILDDDDILLKSKRVREKMVGVGINYVRDLEISPAVKESVTFDLLDQTRKTTVKEFLAQWRGVNNRRYAFSGFQAVEERQILMNTFEKEREFLYELLDGVELSEAQYIYDVYSELLISESLVLDYRE
>NZ_CP019323.1|WP_083685902.1|505934_506642_-|cation:proton-antiporter
MDLYISAVIILVLVAISNLAAKFIKVIPRTYINLFMGIIFACIPLISKLVIGFDSEFFMSFVIAPLLFFDGQQTRSFLVQRKFKEILGTAIILALISATVGLFAVNKIFKVGLPLALIMIAISTPTDATALDSVREGRDVPKRTEVVLKMESLFNDASGIILLQAAVLWFKTGELSYTRNFGDFLISAVGGVILGAGVAFITMVIRQMIIRSRFNETSSHLLIYFATPILIYLVA
>NZ_CP019323.1|WP_076613983.1|506753_507920_-|pyridoxal-phosphate-dependent-aminotransferase
MSYDFDKEFDRRNTNSEKWDVLENELPMWIADMDFQTAPEIMEAMKKSIDGGIFGYQFVPDSYYEAVKNWFELEHNFKPETDWMVFSTGVMPSISAIIRHLTDVGDNILLQEPNYNSFYKAIESNGRNVTNSELTYKNDAYQIDWEDLKNKLSDPQTTVMIVCNPHNPTGHIWDAKTLSRIGQLAKDNDVLIISDEIHGDLSMPNNSYIPFASLDESIIDNSISLVSPTKTFNLAMLHASTLFVPNENLRNKVRRAISIDGHNEPGILAIDGTIAAYTKGHDWLSELRQYISINRQLLSDYVAKNIPELTVLKSDATYLAWIDCTKVTDDSAELNEFIRKETGLYLAEGTKYRGNGSEFLRMNLATNKSRVQDGLNRLERGIHAYINK
>NZ_CP019323.1|WP_076613984.1|508058_509474_+|amino-acid-permease
MPSFFRKKDVINDLKNKDTVLERTLGSKDLIIMGVGVIVGSGIFITPGIIAANYAGPGVIFTYLFAALVCIGAAFCYSEFASTIPLAGSAYTYSYSVYGEVVAWIVGWSLVSEYLFAAASTAVSWSAYFRNLLAGFGITLPKALQSAANTSGNSQGRFDIIAFVIVLLATVLLLQGLTESVKINAIMVYVKIFVILLFVVVAAFFVKPKNYSPFLPFGWSGIGKGASVAFYAFLGFDVVSTASEEVKNPKRNMPIGIIASLLIVAVLYSLVSFVLVGAVNYKQLNVADPVAHALNILNQNWASGIISLGAVMGMTTVLLVIMYGGTRLIYSFSRDGLLPKGFKSVNKNSIPANSTVLVGLAAAIAAAVLPIEKITELVNIGTLLAFASTSIGVIFLRHGKNTRDLKPAFKVPLYPIFPLISFFACIYLMTQLQPFTWHMYGIWTGIGLVIYFGYGYGHSLINKKKANSKRI

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP019323_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019323_5

577658-577753

Orphan

Consensus_repeat	Method
GCGTGACAAAACACAATTTTCTCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP019323_5

>merge|NZ_CP019323|5|577658-577753|CRISPRCasFinder
GCGTGACAAAACACAATTTTCTCCATAGAATTTAAGAAGTAGCTGTGGCATAACTCGTTTTCTAGCGAAAACGCGTGACAGAACACAATTTTCTCC

>NZ_CP019323|5|5|577658-577753|CRISPRCasFinder
GCGTGACAAAACACAATTTTCTCC	ATAGAATTTAAGAAGTAGCTGTGGCATAACTCGTTTTCTAGCGAAAAC
GCGTGACAGAACACAATTTTCTCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019323.1\|WP_076614050.1\|571725_573168_+\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
NZ_CP019323.1\|WP_076614060.1\|586476_587241_+\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
NZ_CP019323.1\|WP_076614054.1\|577847_578819_-\|polyprenyl-synthetase-family-protein	unknown	unknown	gnl\|CDD\|173833
NZ_CP019323.1\|WP_076614061.1\|587370_587958_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP019323.1\|WP_076614047.1\|568833_569589_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133381
NZ_CP019323.1\|WP_083685906.1\|584938_586213_-\|PTS-sugar-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|224372
NZ_CP019323.1\|WP_076614056.1\|579812_581009_-\|acetate-kinase	unknown	unknown	gnl\|CDD\|234680
NZ_CP019323.1\|WP_076614046.1\|568273_568816_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NZ_CP019323.1\|WP_076614048.1\|569724_570537_+\|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	unknown	unknown	gnl\|CDD\|238574
NZ_CP019323.1\|WP_076614062.1\|587966_589115_+\|cation:proton-antiporter	unknown	unknown	gnl\|CDD\|223551
NZ_CP019323.1\|WP_076614053.1\|575910_577653_+\|thiol-reductant-ABC-exporter-subunit-CydC	unknown	unknown	gnl\|CDD\|227320
NZ_CP019323.1\|WP_076614057.1\|581146_583063_+\|accessory-Sec-system-glycosyltransferase-Asp1	unknown	unknown	gnl\|CDD\|224117
NZ_CP019323.1\|WP_076614059.1\|584112_584934_-\|tyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|379135
NZ_CP019323.1\|WP_076614055.1\|578901_579816_+\|1,4-dihydroxy-2-naphthoate-polyprenyltransferase	unknown	unknown	gnl\|CDD\|235695
NZ_CP019323.1\|WP_076614058.1\|583134_584067_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133030
NZ_CP019323.1\|WP_076614052.1\|574178_575924_+\|thiol-reductant-ABC-exporter-subunit-CydD	unknown	unknown	gnl\|CDD\|227321
NZ_CP019323.1\|WP_076614044.1\|565577_566300_+\|DUF975-family-protein	unknown	unknown	gnl\|CDD\|283754
NZ_CP019323.1\|WP_076614043.1\|564630_565398_-\|pyrroline-5-carboxylate-reductase	unknown	unknown	gnl\|CDD\|223422
NZ_CP019323.1\|WP_076614051.1\|573164_574178_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|376764
NZ_CP019323.1\|WP_076614049.1\|570573_571584_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223769

Protein	Function_ID	Function_description	E-value
NZ_CP019323.1\|WP_076614050.1\|571725_573168_+\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	0
NZ_CP019323.1\|WP_076614060.1\|586476_587241_+\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	3.25092e-32
NZ_CP019323.1\|WP_076614054.1\|577847_578819_-\|polyprenyl-synthetase-family-protein	gnl\|CDD\|173833	cd00685, Trans_IPPS_HT, Trans-Isoprenyl Diphosphate Synthases, head-to-tail. These trans-Isoprenyl Diphosphate Synthases (Trans_IPPS) catalyze head-to-tail (HT) (1'-4) condensation reactions. This CD includes all-trans (E)-isoprenyl diphosphate synthases which synthesize various chain length (C10, C15, C20, C25, C30, C35, C40, C45, and C50) linear isoprenyl diphosphates from precursors, isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). They catalyze the successive 1'-4 condensation of the 5-carbon IPP to allylic substrates geranyl-, farnesyl-, or geranylgeranyl-diphosphate. Isoprenoid chain elongation reactions proceed via electrophilic alkylations in which a new carbon-carbon single bond is generated through interaction between a highly reactive electron-deficient allylic carbocation and an electron-rich carbon-carbon double bond. The catalytic site consists of a large central cavity formed by mostly antiparallel alpha helices with two aspartate-rich regions (DDXX(XX)D) located on opposite walls. These residues mediate binding of prenyl phosphates via bridging Mg2+ ions, inducing proposed conformational changes that close the active site to solvent, protecting and stabilizing reactive carbocation intermediates. Farnesyl diphosphate synthases produce the precursors of steroids, cholesterol, sesquiterpenes, farnsylated proteins, heme, and vitamin K12; and geranylgeranyl diphosphate and longer chain synthases produce the precursors of carotenoids, retinoids, diterpenes, geranylgeranylated chlorophylls, ubiquinone, and archaeal ether linked lipids. Isoprenyl diphosphate synthases are widely distributed among archaea, bacteria, and eukareya.	1.38838e-80
NZ_CP019323.1\|WP_076614061.1\|587370_587958_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	4.90096e-14
NZ_CP019323.1\|WP_076614047.1\|568833_569589_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133381	cd01106, HTH_TipAL-Mta, Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA. Helix-turn-helix (HTH) TipAL, Mta, and SkgA transcription regulators, and related proteins, N-terminal domain. TipAL regulates resistance to and activation by numerous cyclic thiopeptide antibiotics, such as thiostrepton. Mta is a global transcriptional regulator; the N-terminal DNA-binding domain of Mta interacts directly with the promoters of mta, bmr, blt, and ydfK, and induces transcription of these multidrug-efflux transport genes. SkgA has been shown to control stationary-phase expression of catalase-peroxidase in Caulobacter crescentus. These proteins are comprised of distinct domains that harbor an N-terminal active (DNA-binding) site and a regulatory (effector-binding) site. The conserved N-terminal domain of these transcription regulators contains winged HTH motifs that mediate DNA binding. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Unique to this family, is a TipAL-like, lineage specific Bacilli subgroup, which has five conserved cysteines in the C-terminus of the protein.	1.59094e-42
NZ_CP019323.1\|WP_083685906.1\|584938_586213_-\|PTS-sugar-transporter-subunit-IIC	gnl\|CDD\|224372	COG1455, CelB, Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism].	2.21451e-111
NZ_CP019323.1\|WP_076614056.1\|579812_581009_-\|acetate-kinase	gnl\|CDD\|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	0
NZ_CP019323.1\|WP_076614046.1\|568273_568816_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	3.79469e-27
NZ_CP019323.1\|WP_076614048.1\|569724_570537_+\|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	gnl\|CDD\|238574	cd01169, HMPP_kinase, 4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of the hydroxyl group of HMP to form 4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate (HMP-P) and then the phophorylation of HMP-P to form 4-amino-5-hydroxymethyl-2-methyl-pyrimidine pyrophosphate (HMP-PP), which is the substrate for the thiamine synthase coupling reaction.	6.44972e-108
NZ_CP019323.1\|WP_076614062.1\|587966_589115_+\|cation:proton-antiporter	gnl\|CDD\|223551	COG0475, KefB, Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	3.14424e-63
NZ_CP019323.1\|WP_076614053.1\|575910_577653_+\|thiol-reductant-ABC-exporter-subunit-CydC	gnl\|CDD\|227320	COG4987, CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	1.29987e-158
NZ_CP019323.1\|WP_076614057.1\|581146_583063_+\|accessory-Sec-system-glycosyltransferase-Asp1	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	2.19774e-10
NZ_CP019323.1\|WP_076614059.1\|584112_584934_-\|tyrosine-protein-phosphatase	gnl\|CDD\|379135	pfam13350, Y_phosphatase3, Tyrosine phosphatase family. This family is closely related to the pfam00102 and pfam00782 families.	2.01112e-63
NZ_CP019323.1\|WP_076614055.1\|578901_579816_+\|1,4-dihydroxy-2-naphthoate-polyprenyltransferase	gnl\|CDD\|235695	PRK06080, PRK06080, 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated.	7.82137e-66
NZ_CP019323.1\|WP_076614058.1\|583134_584067_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|133030	cd04187, DPM1_like_bac, Bacterial DPM1_like enzymes are related to eukaryotic DPM1. A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily.	5.85064e-76
NZ_CP019323.1\|WP_076614052.1\|574178_575924_+\|thiol-reductant-ABC-exporter-subunit-CydD	gnl\|CDD\|227321	COG4988, CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	0
NZ_CP019323.1\|WP_076614044.1\|565577_566300_+\|DUF975-family-protein	gnl\|CDD\|283754	pfam06161, DUF975, Protein of unknown function (DUF975). Family of uncharacterized bacterial proteins.	2.58991e-19
NZ_CP019323.1\|WP_076614043.1\|564630_565398_-\|pyrroline-5-carboxylate-reductase	gnl\|CDD\|223422	COG0345, ProC, Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism].	7.27053e-72
NZ_CP019323.1\|WP_076614051.1\|573164_574178_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|376764	pfam02322, Cyt_bd_oxida_II, Cytochrome bd terminal oxidase subunit II. This family consists of cytochrome bd type terminal oxidases that catalyze quinol-dependent, Na+-independent oxygen uptake. Members of this family are integral membrane proteins and contain a protohaem IX centre B558. One member of the family, Klebsiella pneumoniae CydB, is implicated in having an important role in micro-aerobic nitrogen fixation in the enteric bacterium Klebsiella pneumoniae. The family forms an integral functional unit with subunit I, family Bac_Ubq_Cox, pfam01654.	2.47441e-89
NZ_CP019323.1\|WP_076614049.1\|570573_571584_+\|hypothetical-protein	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	4.52582e-08

>NZ_CP019323.1|WP_076614053.1|575910_577653_+|thiol-reductant-ABC-exporter-subunit-CydC
MNFFKTFKGDTWVKPYIKQYKGLLITVLLLGLVTSICASALMFTSGYTIDKAATHPVNILLIYVPILLTRAFGIGRPTFKYIERLKSHNWVLRVTSNLRTRLYTTLESDAAFLNEHHKTGDIMGLLSEDISHLQNLYLRTVFPTVISYLLTIIGSLVLGIYNPAFGFFVFLLLAIEVLIVPLVSVSIESARRVRQKQIKANLYTNLTDNILGADDWIISGRQKDFKNLSSSNISELNNSKDKSKSFRRNRDLFLQLIFVGIAICFIIFTNLTMTDGQEQANFVSAVVLCLFPLSETFIPVSQGYEEWPEYRDSIIRLNSLKPVESNLPKQAQLDPKKFEKIDIENIDFEYDADSPVLIKNFSQTIQKGQKIALLGPSGIGKTTILQLILGDLIPQSGSIKVNEKNVQELQEHREQIFSVLNQKPFLFNTSVMNNVRLGNESKSDSEVKAALEKVGLKDLIETLPDKYNTLVGENGSNFSGGEQERLALARILLQDAPVVLLDEPTVGLDPITENDLLKTFFTVLADKTIIWVTHHLQGINYVDHVIFMNSKEIEMQGSPTDLYKTNKHFRELYKMDQGFK
>NZ_CP019323.1|WP_076614052.1|574178_575924_+|thiol-reductant-ABC-exporter-subunit-CydD
MIDKRLLSLPGTKRLFIMLAGLTFLQAFAILFQGKYLAEALVNSWEQKSLQTIILPMSLFAVAFLLRHCFNWINNKVVENYAENTSEEIRSKLLDKVYTSGPSMISEEGTGNLVTASLDGIDLIENYFKLIFTKLMNMSIIPPVLLIYIYTQNLASGITLTVIVPLVILFMIILGLAAQAKADSQYHQYTILSNHFLDALRGLPTLKMLGLSKRYAKNIYTVSDEYRRRTMNTLRIAILSTFALDWLTTLGIAILAVFLGLGLINNSFPLFPALVTLILAPEYFLPLRDFSSDYHATLNGKNALNSIFDILNYKDTDTEDGLESLEWNEKSEVDIKNLVFNYSRDQSNIDSSLDIDHLKLSGYKNIGVIGKSGSGKTTLIRALGGFLTPDSGVITINDKSIEHFKQRSWQNELTFLPQSPYLFATTIAENIAFYKPDATKEEIQAAAKKAGLTEFIDTLSLGYQTIIGEGGRGISGGQQQRIMLARAFLAKDRHVLIFDEPTAHLDIETEYALKKPMEELFKNHLVIFATHRLHWIQEMDYVIVMSNGQIAEQGTPEDLSKHNGAYSKLISNMRGDQNELL
>NZ_CP019323.1|WP_076614051.1|573164_574178_+|cytochrome-d-ubiquinol-oxidase-subunit-II
MTLANLWFILIGLLFSIFLFLEGFDFGVGMSTRFLAKDFDERLALMTSIGPHWDGNETWLVTAGGAMFASLPLMYASLFSGYYIVLLLVLVGLILRGVSFEFVKHAETRTGKNIWMWTFFVGSFMAPFLLCLMLLSMVQGIPMNANGDAFPKFFDVVNLLSVVGGVAGTLLSLVHGLNFIRLRVEGPLRDRARKLNQILYPILFLGEVVFAVLVFFQTDFFTKRFGSSLFITVLIVLFSLLGYYGVLKDKEGFSFAGSGLSLSMVIVLLFNGLFPRVMIATNPAHSILIKNAANSHYTLTIMTIVAAILIPIVAIYFIWSYTLFTKRINPREHTVKY
>NZ_CP019323.1|WP_076614050.1|571725_573168_+|cytochrome-ubiquinol-oxidase-subunit-I
MLDIGLSIVSLARFQFAMTTVFHFFFVPFSIGMAVLVATMETLYAVKKDKVYLDMAKFWGKIFLLSFAVGIVTGIIQEFQFGMNWSEYSRFMGDVFGAPLAIEALLAFFIESVFIGIWMFTWDRFKPGLHALMIWMTAIGTMLSAIWILAANSFMQHPTGFKINNTTGRIQLTDFGAVITNPQLWRVFPHVILAAIMTAGCVIAGMSAWGLLRKKKDENHFFKVSLRFGLWVSLIFAILSAGAGDLQTQQIIKDQPMKFAATEGIYKDTKDPAPWTVVEAIDAKNHTASSQVEIPKVLSILAYHRLSGSVKGMNSINKELHAKYDKKFGKDMNYYTPPKTLFWSFRVMTGIDLLVMLIAFLGVIWSRKKKDTIENKKWFMVIVGLAIWVPFIGNSAGWFITEFGRYPWIVYGLFTIADAVSPTSTVGTLLFSNIVYFLLFTLLGGVMIWYSRQTLHHGPYYEMEDSKQNVDPFAKEAFVK
>NZ_CP019323.1|WP_076614049.1|570573_571584_+|hypothetical-protein
MVRITKISAGTILLILSIILMIKSGFENFIAALVGTGAIGGAAGILLAITYIIAAAVYILTNRSYSVVPDVVSFVILILGGLMGLFNSSLPGTKFLVIWSWIGIVIGAIVLIISIADLILHPATEEDEEPLDDNYDQPNNYQQNQNNQYPQQNYYQQPMQYQDPNQNQFGQSPYQQPNPQFNQGQNGYQGQNPQFNQNQGSYQNNQYNNQNRQPNQYPQNNFNPQFNQQNQPNRQFGSSQQSQQTNYPVPTNNGQFNRNNQINNNQMNHNNQPNRPNQFGNMNQNNQMGQQTMNRQFGQQQQGFNPQQNPNQPNQAPTNGPYGFKNFDPTKSRSHK
>NZ_CP019323.1|WP_076614048.1|569724_570537_+|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase
MMNEFIQVLTIAGSDSDGSAGAQADLKTFMARGVYGMSVLTAAVAGNSYGIHDSINMPSSFIKSQIKDIKDDFNVSAFKTGMLSDSEIIRTVAEEIKDKPFGTFVLDPVIITKHGAMLLESEAYQTLIDELFPLADLITPNFYEAKKLSGLELNNHEEIVEAAHKLRDLGPKNIMIKGEHADESMDSVEDFVLLEDGQSFWISEPYVKTEHVNGTGDTLSSSIVAEIAKGESMENAIRISKTFTYHAIKNEIAVGHKYGPINHFIKDDVK
>NZ_CP019323.1|WP_076614047.1|568833_569589_-|MerR-family-transcriptional-regulator
MEYTIKQLADLAGVSTRTLRYYDQIDLLKPKYNSKNNYRIYGEKQIDRLQQILFYRALEFSLSKIKQLMNDDDYSELTALKEQQELLVLKQRNLDELLNTVNATIKAKQEKITMTDNDKFEAFKNIKIKENESEFGKEIRDKYGDDVVDESNHKFAGLRQVDIKKMKKIEEDMFVNLLKVDESDLDSVYAKLVYEDHKKWLSYSLPNYSASTHRGLVDMYITDKRFSDYYNNKANKPVVQLLRDVVYHYTK
>NZ_CP019323.1|WP_076614046.1|568273_568816_-|GNAT-family-N-acetyltransferase
MSGKVDWVVDEHIKLRIVKPDDDSDLFALVDENRQQLEKYMPWAQDTKTVANEHRFLEYCQKQITKKALWPVTILVDGKVAGMFDFHDFDHADRHCSIGYWLGKGYQHNGVMTRVVKAAIKIGFEELDMHKIALLAEVENTSSNNVAIRNGFHLDGTLKEHIYSDGKFHDANIYSMLEHS
>NZ_CP019323.1|WP_076614044.1|565577_566300_+|DUF975-family-protein
MKNYHSRAELKREVKNLLKRRWTTGVLLYLIPLLITGMGNTANNHNPNTKFVYGSTDFYVNFTMLFRVLAITGIITFILGVIFSLISISATFRGLDWVNDPELDVQPLKSNFTYFRSPDWWKLMLTYLLVNVFTFLWSLLLIVPGIIKMFSYSQTYFIYKDLNDRNLADDYSLTDYITKSKELMSGNKWRYFVLQLSFLGWFILGGVTVIGMLWVFPYYKLTMANFYKDLAEQNKDILGY
>NZ_CP019323.1|WP_076614043.1|564630_565398_-|pyrroline-5-carboxylate-reductase
MIGFIGAGSIGGAVITGLIKNGYDAKEIVVKGGKSNRTKALQEHLGFKLVQKIKQLEDVNPIFIGVGANALDSVLLELKSISKDKLIIAFTGNATVAKLRQSLPDAKVAHAIPNTPVKVGAGFTGITYSEKFTEQEKKQVISIMGYTGQLVEVPETQLGILGTVAGCSPAFLDLFIEALSDAGVKHGLNRKLAYDAAIGMALGSSKLALQSDLNPSALKDEVTSPGGSTIKGVAALEEYGFRNAVIKAVDAAEGE
>NZ_CP019323.1|WP_076614054.1|577847_578819_-|polyprenyl-synthetase-family-protein
MAHSIWKDYPQVDSKLDQTTAFIHSSVKIRNRQISQMIIDLTSGGKMLRPAFFLLFSSFGPDRKPDEVLIPLAASVELLHVATLIHDDVIDDSPLRRGKTTIHTRYGKRNAIYAGDYLFTLYFEMISRYSVKKSDILLNSLSMKKILIGELDQMLINYNVDATAKMYIREVSGKTAELFSLSTEMGAIVSGADEKLTSLSRNIGHDIGMSFQIIDDILDFSDSRVTGKPNLEDLKNGVYTLPYILGLQDKNERLINILSESDLSDSDIKKAADIIENEGYLDSAKDIARTYNQHALKRINRLPNNTNKIVLKKVVNKLLRRIK
>NZ_CP019323.1|WP_076614055.1|578901_579816_+|1,4-dihydroxy-2-naphthoate-polyprenyltransferase
MKPSVFFELVEIKAKTASVFPFLMGTLYSYYHWQSINALDLILFFIAMFLFNMAVDINDNYWDYKNATGAESFRRNTNVIGVNHLNIHLIGWIDFTFTVVAALIGIFIVYRTGLPLLFMGIFSFAVGFLYAGGPHPINRGPLGEFFSGFTMGFVIYLISIYINVFDSPAVILDFKFYGDALLSSLLTVFSISNLLLANNIADEEEDKTLGRKTLVYYLTKDNSIFILKSLYVLGFLALTCSVIIGLLPKMMLLTFLIAPIVYKNTKSFCDNPIKKETFPFIIKNLLMITLTEVVTFLIGVLTNF
>NZ_CP019323.1|WP_076614056.1|579812_581009_-|acetate-kinase
MKIMAINAGSSTLKWKLFEMPEKKTIASGMIDRLGSPKSIFKLKYNGEKIEHEEAIESNDIAVLSVLDALKERHIIERFEDIAAFGHRVVAGGEEFKNSEIVTEENLDKILQLSEYAPLHNKIEAYYINVFKKLVPRAIEVAVFDTSFFTDIPAVNYLYSVDLDDYKQFKARRYGAHGTSHRYIAQRLNELVDGGIEDKNVIVMHLGSGASISAIKNGKAVDISMGFTPLSGITMSTRSGDIDVSILPYLMKKLGLTDIDDMIDILNHKSGLLGISGVSADMRDIEAVEDTNKRAKLALDIFRNRIIKYVGSYIAEMGGVDVLAFTAGVGENSPEVRGDILEAFSYLGIKIDADNNKLRGKEVRITTDDSKIAAYTVPTDEELMIAQDTYKFAQLLTL
>NZ_CP019323.1|WP_076614057.1|581146_583063_+|accessory-Sec-system-glycosyltransferase-Asp1
MKFLDMLRKLDNEPEKSSTSTDSASTQAPKDNSDSTEKVEENNLNNEVAEQKEQLPVTTHDKRVNIEEQMDSLSNHYAQLRNDLKTNLFSEKDEHETKKETLDKYLNTLKRDQKESNEKLADIKAQNDDAEIERLAGVHADQKEQQELLNQFKEQQQALSDKLTDANDQLNNKQDELEKNEKSETDMSASIKEEKDLQKMMVLMENQKNSIDKLYKERANVQKDIDNIKADINSLQENVDNVNKNLNSTTSTLDLLKSKVNQIEDKIKNDKNYRIETTAGLERHLQSLADERETIEGELKEVNDNIDYLEKYIKDVFHSAYLVRDVYLDSDKDYYVVADSFDAESKQDVFDTIKLIETKLQKPVTLVSTFYNNHLNDIIDKSAKKSNIHIPNVVSLFDQLQASSNPTTNTVSIPENDGWVTRTDVKTHDTVIYDQSNTLLMTVEYSEDKKIDRINYYKNDQVVKTNLYNDAGQLSSVKNFNKEKVLTEHNFYRTDGSIVLTVIFEDQKAISYQLFDKNGLLEHDFNNKSELINWWLESISPNTDNAIFIGNNNDLLYNLLIKADNLDSKSTIPLLQNVSENIKDIISMLDKNTDITNILVQYSKDLHAIESETNRDICVSVIRSSASGELALPESLEI
>NZ_CP019323.1|WP_076614058.1|583134_584067_+|glycosyltransferase-family-2-protein
MKTISVIVPCYNEEETINLYYDAMTKVKNEKNKFNFEYWFIDDGSSDKTLKVLKELQAKHSDEVHYISFSRNFGKEAALYAGINEVKGEYTAVMDVDLQDPPEMLEEMFDTLEEGEYDCVGTARMDREGENPIISFFSNSFYGVINKMSQTKIVSGARDFRLMTRQMVDAILSMTEYNRFSKGIFSWVGFKTKYLPYKNRKRVAGETSWNFWKLFKYAVTGIIDFSERPLMFATWMGVFFSGISILAIIGIIIRKLVFPLSSVTGWASMVSIILLIGGIQLLSIGILGEYIGKIFLEVKRRPIYIVKEKK
>NZ_CP019323.1|WP_076614059.1|584112_584934_-|tyrosine-protein-phosphatase
MSEFKNNRLIQLDGTFNTRDLGGYKTEDGRMVKWGRLYRSDDLYTLTPADVQWFVDNHLTTIIDFRNINERINRPDKKIPDTEYYVLSPDDDTAAMASADLKSDKRKIDKLIARKKQGTLDLSVDGLKESMIKLVRDPKAQELYRHVLDLHIARLDAVVLQHCRGGKDRTGYGSALVLFALGVSEQDVIKDYMLTAKYNSARNARRMAEYEQYTDDKVTLQYLANAMSTRKEVIDAGISTMKLIADTPLGYIENVLGFNKQDINKLRKIYLIN
>NZ_CP019323.1|WP_083685906.1|584938_586213_-|PTS-sugar-transporter-subunit-IIC
MGAKMQSFTNKIQSSMGKFASNKLLSAISNGMIRLLPVTMVGSVFAILGNLGFPGYQEFVNKIGFGSIFAMGVQMTTNLISIYVLISLAYEYSKKLNGSKVNSILLSVMSFFLLTPISNFKVKGSAVVGLDLTYLGSKGMFVAMIVSLSVTRLYCLLENKHITIKMPDSVPPAVSNSFTGLVPAWIIAGIVLVINGILRATPFGDIHDLVYTIVQTPLEHLGGSIWALLFILFFSEFLWFFGIHGSMATSAIIYTLYQPLELQNLAAYTAGQALPNILTKTFIDVMKGPRHFALALLLLFICRSHHMKSVGKVAIIPAIFGISEPMKFGIPMVLNPILFIPMTLSPVISVGLAYAATSLKLIPRMTGITFPWNIPVVSGLIVGDWRTAVLQVIQLFIAMALYYPFIKFLDRQTLEQEAEQVEKE
>NZ_CP019323.1|WP_076614060.1|586476_587241_+|MurR/RpiR-family-transcriptional-regulator
MTSAKFDQRIINLTKDLTTNEKSVIDYIHTHTADINKMTISQLAQNVHYSNSFISKVVKKIGYADFAEMRYELKEENEKNDISKEFDVISQQRIDIAKTNSLLLQTKFDSINKLLDEATAVYVYGTGHSQANYIRELSRNLMLLVKVPVILLSGLSEFESVQPSIKKTDCVLIASISGESPTVIKGVKYLVLNKVPIISLTEFSDNTLASLSTYNLFYYSTPIPNPTGRKDVVSFLSLGYCIDFVIREYIDYLN
>NZ_CP019323.1|WP_076614061.1|587370_587958_+|TetR/AcrR-family-transcriptional-regulator
MNSRDKQAENTKNAILRVAAKDFLSQGYQATSTRKIAQELNITQPNMYHYYKNKKVLYAKAIENEVGGFSEKLYAEYNKNKDLPFDEMLTTISTFMVSNFKLNFFMLRHDLDTVFTDDEKKDISKNWDGGYYKVLFNIFQAHKEELRSDLSIPVQVGTFLTMLVPYIEYNEAKRKRNIANLNTMIKIFIHGIKKE
>NZ_CP019323.1|WP_076614062.1|587966_589115_+|cation:proton-antiporter
MEFITLLALMLFLTLIVSHIFNKMNLPAVIGQLILGVILGRGMLNIVKSTNELQLFADIGVILLMFIAGLESDLKLLRKHLGPSITVAIFGVILPVALTLLTSLIFNINMRESIFISVVFAATSVSISVEVLKSLNYLSSTSGTVILGAAVADDILAISILSVMSGTLTGNFSMKKIWTLLALWVLFVIVTYVAYRFIVPAIMKLADYAEATHAPTITALVICLIFAYFADWVQLDSVLGAFVAGIAISNTPNYNSKINRNIEIVGYSVFIPIFFISIGLNLEFTSLLKDFWLIFFFTVTGIFGKLIGAGFGARISGFNMKDSYVIGSGMISRGEMALIVAQVGYSVHLLSEEYYSTVIISIILITILAPFFLKHSISKNPI

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP019323_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019323_6

600507-601400

TypeII

Consensus_repeat	Method
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	PILER-CR
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	CRISPRCasFinder
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	CRT

13 spacers

csn2,cas2,cas1,cas9,cas14j

The CRISPR arrays of NZ_CP019323_6

>merge|NZ_CP019323|6|600507-601400|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACCAAAAAAATTGGTAGTTCTTTCACAGGAGCAGTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACCAAAACGTTAAAAATAAACTGAGTCTCGTGTGTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACCCTAGAACTGCTGACAAAGCGACTTTTGACAGTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACCAATGAAGTACTAGTTAAGAACTTTAATATGGTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACCTGTTCTAAAAATACAAGAGGCAACCAAGCGGTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACCATATATGTCACGTAGCAAATCAGTAAACTTGTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACCTGGCGTCAGCGTCAATGTTTGCCATGTTGGGTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACCTGCTTTGAGTAATTCTTCGATTCTGTTCTCGTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACCAATGTTAAACAAGATTGAGAGTCAAGCTACGTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACCTGTAATATGCTATAGTGAGACTATTAAATAGTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACCATTTTTAACGTTCTCAATGAGTAATATTGAGTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACCATCTCCTAAAGCAACAATCACGCAGCTAGAGTTTTAGTAGTATGTCTTTCTTAGTAGTTTAGAACCAATATTGAGTGAGCCCCGTACAGTAACACGGTTTTAGCAGTATGTCTTTCTTAGTAGTTTAAAAAC

>NZ_CP019323|6|1|600507-601334|PILER-CR
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	AAAAAAATTGGTAGTTCTTTCACAGGAGCA
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	AAAACGTTAAAAATAAACTGAGTCTCGTGT
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	CTAGAACTGCTGACAAAGCGACTTTTGACA
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	AATGAAGTACTAGTTAAGAACTTTAATATG
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	TGTTCTAAAAATACAAGAGGCAACCAAGCG
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	ATATATGTCACGTAGCAAATCAGTAAACTT
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	TGGCGTCAGCGTCAATGTTTGCCATGTTGG
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	TGCTTTGAGTAATTCTTCGATTCTGTTCTC
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	AATGTTAAACAAGATTGAGAGTCAAGCTAC
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	TGTAATATGCTATAGTGAGACTATTAAATA
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	ATTTTTAACGTTCTCAATGAGTAATATTGA
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	ATCTCCTAAAGCAACAATCACGCAGCTAGA
GTTTTAGTAGTATGTCTTTCTTAGTAGTTTAGAACC

>NZ_CP019323|6|6|600507-601400|CRISPRCasFinder
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	AAAAAAATTGGTAGTTCTTTCACAGGAGCA
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	AAAACGTTAAAAATAAACTGAGTCTCGTGT
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	CTAGAACTGCTGACAAAGCGACTTTTGACA
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	AATGAAGTACTAGTTAAGAACTTTAATATG
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	TGTTCTAAAAATACAAGAGGCAACCAAGCG
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	ATATATGTCACGTAGCAAATCAGTAAACTT
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	TGGCGTCAGCGTCAATGTTTGCCATGTTGG
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	TGCTTTGAGTAATTCTTCGATTCTGTTCTC
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	AATGTTAAACAAGATTGAGAGTCAAGCTAC
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	TGTAATATGCTATAGTGAGACTATTAAATA
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	ATTTTTAACGTTCTCAATGAGTAATATTGA
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	ATCTCCTAAAGCAACAATCACGCAGCTAGA
GTTTTAGTAGTATGTCTTTCTTAGTAGTTTAGAACC	AATATTGAGTGAGCCCCGTACAGTAACACG
GTTTTAGCAGTATGTCTTTCTTAGTAGTTTAAAAAC

>NZ_CP019323|6|1|600507-601400|CRT
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	AAAAAAATTGGTAGTTCTTTCACAGGAGCA
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	AAAACGTTAAAAATAAACTGAGTCTCGTGT
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	CTAGAACTGCTGACAAAGCGACTTTTGACA
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	AATGAAGTACTAGTTAAGAACTTTAATATG
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	TGTTCTAAAAATACAAGAGGCAACCAAGCG
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	ATATATGTCACGTAGCAAATCAGTAAACTT
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	TGGCGTCAGCGTCAATGTTTGCCATGTTGG
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	TGCTTTGAGTAATTCTTCGATTCTGTTCTC
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	AATGTTAAACAAGATTGAGAGTCAAGCTAC
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	TGTAATATGCTATAGTGAGACTATTAAATA
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	ATTTTTAACGTTCTCAATGAGTAATATTGA
GTTTTAGTAGTATGTCATTCTTAGTAGTTTAGAACC	ATCTCCTAAAGCAACAATCACGCAGCTAGA
GTTTTAGTAGTATGTCTTTCTTAGTAGTTTAGAACC	AATATTGAGTGAGCCCCGTACAGTAACACG
GTTTTAGCAGTATGTCTTTCTTAGTAGTTTAAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019323.1\|WP_076614068.1\|598588_599467_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP019323.1\|WP_076614070.1\|599773_600172_+\|hypothetical-protein	csn2	cd12218_csn2_CAS-II-A	gnl\|CDD\|213411
NZ_CP019323.1\|WP_076614076.1\|606645_607554_-\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_CP019323.1\|WP_076614064.1\|590629_591397_+\|DUF1003-domain-containing-protein	unknown	unknown	gnl\|CDD\|226844
NZ_CP019323.1\|WP_076614074.1\|604266_604968_+\|glucosamine-6-phosphate-deaminase	unknown	unknown	gnl\|CDD\|238693
NZ_CP019323.1\|WP_192844209.1\|610044_611433_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	unknown	unknown	gnl\|CDD\|235392
NZ_CP019323.1\|WP_076614075.1\|605088_606462_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|129987
NZ_CP019323.1\|WP_083685907.1\|600099_600480_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd12218_csn2_CAS-II-A	gnl\|CDD\|213411
NZ_CP019323.1\|WP_076614063.1\|589202_590390_+\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224172
NZ_CP019323.1\|WP_076614073.1\|603203_604070_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP019323.1\|WP_076614069.1\|599471_599777_+\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0206_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|226043
NZ_CP019323.1\|WP_076614062.1\|587966_589115_+\|cation:proton-antiporter	unknown	unknown	gnl\|CDD\|223551
NZ_CP019323.1\|WP_076614065.1\|591462_593493_+\|KUP/HAK/KT-family-potassium-transporter	unknown	unknown	gnl\|CDD\|376906
NZ_CP019323.1\|WP_076614066.1\|593619_594177_-\|cysteine-hydrolase	unknown	unknown	gnl\|CDD\|238245
NZ_CP019323.1\|WP_076614078.1\|608134_610036_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	unknown	unknown	gnl\|CDD\|235362
NZ_CP019323.1\|WP_076614077.1\|607696_608050_-\|DUF1801-domain-containing-protein	unknown	unknown	gnl\|CDD\|227933
NZ_CP019323.1\|WP_076614067.1\|594335_598433_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	mkCas0193_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|374653
NZ_CP019323.1\|WP_076614080.1\|611580_612423_-\|membrane-protein-insertase-YidC	unknown	unknown	gnl\|CDD\|179508
NZ_CP019323.1\|WP_076614072.1\|601818_603072_+\|transposase	cas14j	-	gnl\|CDD\|223747
NZ_CP019323.1\|WP_076614081.1\|612452_612794_-\|ribonuclease-P-protein-component	unknown	unknown	gnl\|CDD\|234782

Protein	Function_ID	Function_description	E-value
NZ_CP019323.1\|WP_076614068.1\|598588_599467_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.40748e-97
NZ_CP019323.1\|WP_076614070.1\|599773_600172_+\|hypothetical-protein	gnl\|CDD\|213411	cd12218, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	1.48629e-05
NZ_CP019323.1\|WP_076614076.1\|606645_607554_-\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.71745e-45
NZ_CP019323.1\|WP_076614064.1\|590629_591397_+\|DUF1003-domain-containing-protein	gnl\|CDD\|226844	COG4420, COG4420, Predicted membrane protein [Function unknown].	3.32316e-52
NZ_CP019323.1\|WP_076614074.1\|604266_604968_+\|glucosamine-6-phosphate-deaminase	gnl\|CDD\|238693	cd01399, GlcN6P_deaminase, GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or deamination. It is the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate (GlcNAc6P). GlcN6P deaminase is a hexameric enzyme that is allosterically activated by GlcNAc6P.	3.92275e-116
NZ_CP019323.1\|WP_192844209.1\|610044_611433_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	gnl\|CDD\|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
NZ_CP019323.1\|WP_076614075.1\|605088_606462_+\|amino-acid-permease	gnl\|CDD\|129987	TIGR00909, putative_amino_acid_transporter, amino acid transporter. [Transport and binding proteins, Amino acids, peptides and amines].	1.98909e-107
NZ_CP019323.1\|WP_083685907.1\|600099_600480_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213411	cd12218, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	4.10113e-27
NZ_CP019323.1\|WP_076614063.1\|589202_590390_+\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	2.07557e-109
NZ_CP019323.1\|WP_076614073.1\|603203_604070_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	7.23677e-22
NZ_CP019323.1\|WP_076614069.1\|599471_599777_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	6.80001e-25
NZ_CP019323.1\|WP_076614062.1\|587966_589115_+\|cation:proton-antiporter	gnl\|CDD\|223551	COG0475, KefB, Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	3.14424e-63
NZ_CP019323.1\|WP_076614065.1\|591462_593493_+\|KUP/HAK/KT-family-potassium-transporter	gnl\|CDD\|376906	pfam02705, K_trans, K+ potassium transporter. This is a family of K+ potassium transporters that are conserved across phyla, having both bacterial (KUP), yeast (HAK), and plant (AtKT) sequences as members.	0
NZ_CP019323.1\|WP_076614066.1\|593619_594177_-\|cysteine-hydrolase	gnl\|CDD\|238245	cd00431, cysteine_hydrolases, Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It also contains isochorismatase, an enzyme that catalyzes the conversion of isochorismate to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of the vinyl ether bond, and other related enzymes with unknown function.	1.86925e-48
NZ_CP019323.1\|WP_076614078.1\|608134_610036_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	gnl\|CDD\|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
NZ_CP019323.1\|WP_076614077.1\|607696_608050_-\|DUF1801-domain-containing-protein	gnl\|CDD\|227933	COG5646, COG5646, Uncharacterized conserved protein [Function unknown].	1.66997e-20
NZ_CP019323.1\|WP_076614067.1\|594335_598433_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|374653	pfam16592, Cas9_REC, REC lobe of CRISPR-associated endonuclease Cas9. The REC lobe of Cas9 - the CRISPR-associated endonuclease Cas9 - includes the REC1 and REC2 domains. REC1 forms an elongated, alpha-helical structure consisting of 25 alpha helices and two beta-sheets, whereas REC2 inserted within REC1 adopts a six-helix bundle structure. The REC lobe and the NUC lobe of Cas9 fold to present a positively charged groove at their interface which accommodates the negatively charged sgRNA:target DNA heteroduplex. CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system occurs naturally in bacteria as a defense against invasion by phages or other mobile genetic elements. Cas9 is targeted to specific genomic locations by sgRNAs or single guide RNAs, in order to complex with invading DNA in order to cleave it and render it inactive.	5.2129e-152
NZ_CP019323.1\|WP_076614080.1\|611580_612423_-\|membrane-protein-insertase-YidC	gnl\|CDD\|179508	PRK02944, PRK02944, YidC family membrane integrase SpoIIIJ.	2.96627e-86
NZ_CP019323.1\|WP_076614072.1\|601818_603072_+\|transposase	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	4.51279e-27
NZ_CP019323.1\|WP_076614081.1\|612452_612794_-\|ribonuclease-P-protein-component	gnl\|CDD\|234782	PRK00499, rnpA, ribonuclease P; Reviewed.	1.54586e-48

>NZ_CP019323.1|WP_083685907.1|600099_600480_+|type-II-A-CRISPR-associated-protein-Csn2
MIKQINELVFDSINGYDENFYYDLMPELTKLLKSKELSIDTSNWQNYYDKLQSVIRFYVEFDNKRLLLFHGLERLCSLEQINELNDYLKSVELSVVSLESYPMTLKRPGLNTHVYSIDEDHVRFDY
>NZ_CP019323.1|WP_076614070.1|599773_600172_+|hypothetical-protein
MSPESITIFPYKPFDIEYGMTIFNLQNEEEFSNLLFNLNQLKKHEAFIDDVDQYIHFYVDEEDNLKTSLKQVAMLGDLTSYNINSVGNLKLVFQKIVADNQVINRDKLESLNKLTNLFLIPSMVTTKIFIMI
>NZ_CP019323.1|WP_076614069.1|599471_599777_+|CRISPR-associated-endonuclease-Cas2
MRLMIMFDLPTLTAQDRKNYRQFRKNLLNDGFIMMQESIYTCLLVNGTSAKFLENKINVYAPKKGLIQSLIITEKQYEAMRLITGEKNNRPENRFERLVVI
>NZ_CP019323.1|WP_076614068.1|598588_599467_+|type-II-CRISPR-associated-endonuclease-Cas1
MGWETIYITSRSKLSYKSNHLLVQTVADIQEIPFHHIGCIVIATTQAVITGYLVEKLTQADIKVIFCDSDHNPCAELNGYYSNNNRNQNIEKQFSWPIPKKELLWTSIVTNKIENQINVLKQYNLDTTAIIQEFNQIKDNDKTNREAVIAMKYFPALFGSNFSRGNKEDNINKMLNYGYTILLSSVNQEIIAQGYLTQLGIHHHSNQNDFNLSSDLMEPFRQFVDQIVVEHKDSDFDLETKLDILAVLEKQISYNDKNYILKNAINQHVQNCFKFLDSQKLSVAKVDFKNEV
>NZ_CP019323.1|WP_076614067.1|594335_598433_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MNRKTTKYNVGLDIGTASVGWATTGNNYNLLKAKKRNLWGVRLFNTAETAADRRMNRSIRRRYRRRRNRLNWLDEIFSSELFKTDPGFLNRMKYSWVSKNDKSRTRDNYNLFIDKDFNDQTYYEEYPTIFHLRKRLIENPEKADIRLVYLAIHNILKYRGNFTYEHQKFDVSRMNDGLEYTLKELNQALDQFGLSFPNDTDFKLIGDILVKKDWNPSSKVSRIIKELNPTKDMKQFYTYVIKLLVGNKADLTKLFNIESNELSPISFSSNSIENDLATAEEVLSDEQYNIILLANSIYSTIVLNNILNGKTYISFAQVEKYTEHHEDLMKLKNIWRNDEDTAAVKKARNAYEKYLNNGKYTIQEFYKDIGKYLEEKDDDDSKNALEKIDNNKYLLKQRTSDNGVIPFQLNEAELIKIIDNQSQYYPFLKDNKDKILSLINFRIPYYVGPLQSKDKIQSKDKIQSKDKSGFAWMARKENGPIRPWNFDEKVDREKSSNNFIRRMTSTDTYLIGEPVVPKNSLIYQKYEVLSELNNVKIVSTGEGSENQERLRVEVKQRIFNELFKKYNTVSAKRLKDWLIKESYYSAPEIHGLSDKTKFVSSLSSYRKLSKIFGNDFVDNVKNQDQLEQIIEWQTVFEDREILKLKLNKSNQYDEKQINQLVAIRYQGWGRFSNKLLTQLFVNTKIGNEHEPSNHSIIDLLWQTKSNLMEILRDDKYNFESQIKELNIEDSSDKKPLELVNDLHGSPALKRGIWQAISIVQELSEFMGHAPEHIFIEFTRDDQDSSITKSRYNSLKKRYQDIKQMVTDLAPTLKESLFPTKDLEDLMKDKRNSLSNQRLMLYFSQMGRSLYSDAEIDITRLFTSDYQVDHILPQSYIKDDSLENKALVKASENQRKQDDLLLSKDIIANNLTRWEYLKKAGLMGPKKFANLTRTVVTDRQKEGFINRQLVQTSQMVKNVANILDSIYPDTQVIETRASLGMGFRDSFSNLNKKTWHYEHPEFVKNRNVNDFHHAQDAYISTIVGTYQLKKYPRDNMRLVFNAYSKFFEDVKKKTRQERGKIPAYSSNGFIIGSMFNGKTQVNKNGEIIWDQQIKDSISKTFKFKQYNITKQNYINDGALYKQTILNKNNKELIPLKKDLDPHIYGGYTGDITSYSVLIDVDGKKKLISIPVRIAREITAKRINIKDWISNKVKHKKEIQILIDVVPVGQLVKSGDKGLISLPSGTEIANANQLILDYKETALLSLLEHSTLDNYRFILSGDNEDILQSIYSDLIFKIQKLYPLYSSESKRFNDNLDEFNNCSIYDQFNIIEQILNLLHANSTCANLNFGNIKSTRLGRRSNGYEFSDSDFIYKSPTGLYESIIHID
>NZ_CP019323.1|WP_076614066.1|593619_594177_-|cysteine-hydrolase
MASHEALLIVDYTNDFVADNGALTCGKPGQLIEPNIIKVAEEMRKNGDWVWLPTDLHVPFDHYHPETKLFPAHNVQDTWGRELYGELKPWYEKHADEENLKFFDKTRYSAFAGTDLDMRFRERDVDTIHLAGVCTDICVLHTAIDAYNLNYNIVIHSSCVASFNQLGHDWALEHFEKVLGAKIVK
>NZ_CP019323.1|WP_076614065.1|591462_593493_+|KUP/HAK/KT-family-potassium-transporter
MKKTTSSFSKLGMLITLGIVYGDIGTSPLYVMNAIINDAGNMKSAVPEYIIGSISLIFWTLMLITTIKYVLIAMRADNNHEGGIFALYALVRSKKWLIIPALIGGSALLADGTLTPAVTVTSAMEGLKGQEIGGFTMSNSQSVILILVTIILLTIFIIQKFGAERIGKSFGPIMLIWFSFIGIVGLVNISNDFTVLKALSPVYAIKILTSPVNHAGIFILGSVFLATTGAEALYSDMGQVGKFNIYGTWPFVYITLMLNYLGQGAWVMSHYMDKQYMNLNTVNPFYEMLPGQLKIFAILIATMAAVIASQALITGSFTLVEEAIGLKILPRLRVKFPGNIKSQLYIGSVNWLLCLVTLSVVWGFRTSEHMEAAYGLAITMTMLMTTILLHQFLVMKHHKVGATIFVTFFIILESLFFISSLVKFVHGGYITVIITAIILMIMVIWYYGNKRRDSYLNESQSVSLLDYIPQLEKLSTDTNIPLFATNLVFLNRIEDDYSIKRSIIYSILDQDPKRAKVYWFITVNQTNNPYECNYSVDMMNTRNVVDVQLNLGFKKSQHVNIYIRQIVNALLDEKIIDPQTPDYSMMKNRRVGSFKFVILNEQFQDLGAQEHMKSLDRFLIGGRILLQNMTLPPALWYGLEFSDVTEEKVPLFLGSHVDNYLVKDSVTNVKSEPKNE
>NZ_CP019323.1|WP_076614064.1|590629_591397_+|DUF1003-domain-containing-protein
MSVKKTQSCIICHKRFSPIEGLFLRDLNDSLKQEIIDKNDFAKSSSFVCLRDLQIIRLSKMQHIIDKDLEMDQKMNDEFQKELSKNTYVIRNLNDTIHGELTRGQKLSDAVARFGGSWGFIISFIVILIVWMAFNVVHFLGINFDPYPFILLNLFLSCIAAIQAPIIMMSQNRQAQRDRFDAENDYRTNTKSEMEIRILHEKIDQLNEVQWPHLLDIQKMQVEVLSELENEIQSNRAEQERSNNPQHRRHRNRNQ
>NZ_CP019323.1|WP_076614063.1|589202_590390_+|NAD(P)/FAD-dependent-oxidoreductase
MAHILVLGAGYGGLTAARDLAKSTPAGTQIDLVDKNVLHVEKTGLHMIAAGTTRADAVTFDIHSVLPSNVNFIQACVKDLDLDNKTVHFEDHDDITYDYIVVALGFRSEDFGLEGASDNALILQDLDTAKNIYKTMNKNIANYKDSQDPADLSIVVCGAGFTGIEILGELVDTVKILKAKYGVPEIKVTCLEMATRILPMFDEELANYAVSYLEKNGIKLLTGAKITKIEPKAVVYMDGEEEKQVEGSTILWTVGVSGSDVIKDSGLEARRNRVTTTSFLNIEEHPEAYFIGDDSAMIPEGAERPLPTTGQLASAEGVAVAYNIGAALNGKELKPFVYTSLGTIASLGQNHGIAEILGKGYKFKGHTASLLKHLSGDRSLMEVAGLKTAFKKGTI
>NZ_CP019323.1|WP_076614062.1|587966_589115_+|cation:proton-antiporter
MEFITLLALMLFLTLIVSHIFNKMNLPAVIGQLILGVILGRGMLNIVKSTNELQLFADIGVILLMFIAGLESDLKLLRKHLGPSITVAIFGVILPVALTLLTSLIFNINMRESIFISVVFAATSVSISVEVLKSLNYLSSTSGTVILGAAVADDILAISILSVMSGTLTGNFSMKKIWTLLALWVLFVIVTYVAYRFIVPAIMKLADYAEATHAPTITALVICLIFAYFADWVQLDSVLGAFVAGIAISNTPNYNSKINRNIEIVGYSVFIPIFFISIGLNLEFTSLLKDFWLIFFFTVTGIFGKLIGAGFGARISGFNMKDSYVIGSGMISRGEMALIVAQVGYSVHLLSEEYYSTVIISIILITILAPFFLKHSISKNPI
>NZ_CP019323.1|WP_076614072.1|601818_603072_+|transposase
MKTMPQLPYYYGTKVRIFPSNSQKRLIKKNSDASRFIYNQMAGINQELYFLRQVKIPIKIVQKRIDTLEERLRNPATGISNIHGWLNDKELDSLMKANAIRNYRSAWSMFYKVHNTGIPVFHKKGIEQKYQTSCMYAGKLPITNMNNGNVRLLNNRYIHLPKLGNIRFKGMPKKLLSRKENIRIGTTTVSMDSTGCYYISLQLASEQPFVTVLNINNSSPIGIDLNTDNFITDSDGNTIDNPRYYRSIKGKLAKAQQKLSRRALRAKREHRSLCDSKNYQEQRKIVATIQRRVTNCRKNFLHNVSTTLIKNHDLVVAEELRSKNMLQNHALAMSIADVGWKIFLNMLTYKAELYGQKFITISPYNTTQKCSNCAFVMRGNQKLTLADRKWTCPKCCMHHIRDHNAAKNILNKGLILN
>NZ_CP019323.1|WP_076614073.1|603203_604070_-|alpha/beta-hydrolase
MEKVFEISKGKVNVKVTGDLDSEKTVIALIPGINGTIEYFDEITPLLQEKYTVVALDLLGQGKSTLSDDGKYNIDMQAWSMLEVIARLRITEKIMVFGYGIGGLIAMRMAELRDFAISKFVLLNTPANAKYADMDAHSSLASIPLLGKLAKSPVKSSLYFSKDFDTSKLKNQNVVNDAANTVNRKTDKKLGKIAEEYLEEKALNKRLRVVGLPTLAIFSDGDQILTEAGVKDAKATIGRVPHLVIKDLLGAGHVGMIEKPKEVCDMIVKFDDDTKDFDYTEVESIDDK
>NZ_CP019323.1|WP_076614074.1|604266_604968_+|glucosamine-6-phosphate-deaminase
MNIIKVQDQDLGGKEAFNLIATDIKNGAKVLGLATGSSPITLYKEMTNSDIDFSNITSVNLDEYVGLNADNEQSYHYFMKDHLFSKKPFKNSYVPDGSNSDAKDATSKYDKIIEENPIDVQVLGIGRNGHIGFNEPGSPLDGKTSKVSLTESTIEANKRFFDDEKDVPRYAYSMGIGSIMKAKKIILLAYGENKADAIAKTVNGPVTSDVPASALQNHPDVTIIVDGAAAAKL
>NZ_CP019323.1|WP_076614075.1|605088_606462_+|amino-acid-permease
MLKKLFKKADYKQYIADDSHFSKTLTKNNLIAMGIGSIIGTGIFILPGIVAYATSGPAITISFILAAIVCVLAAMCFAELSSTFPVAGSTYSYGSIIFGQFPGWIVGWALCLEYILGVSAVSSGFSAYFVSMFNNFGIHLPHAITGPFIPSEGTFINLPSIIVLILIYFLLRRGVQSSARMNTIVVFIKLAVIIAFIVIGLFYIKPQNYHPYFPMGGVGVVKGAALVFFAYLGFDVIPSSAPEVKDPQKNIPAGIMISLSICAALYLIMAAVLTGMVNYTKLNVSDPVVFALKEVGLSKITFLISIGALAGMFTMMLNTIYGGSRLVYALGRDKLIPEVFGKIDNKSKMPKTSLNAITILAVLLGGFVSLEELTSLVNIGTLLSFVFVSLGVIKLRQRKDVPKSGFKVPFYPWFPAISAGLCILLMTQVSINSWIASIGWFAIGIGIYFAYGYRKAE
>NZ_CP019323.1|WP_076614076.1|606645_607554_-|Gfo/Idh/MocA-family-oxidoreductase
MKKIGVIGLGNIAQKAYLPVMASLQDKYEWHLTTRNSEKGQKLAKKYGFTHVHQTLDQLIAEQPLAVFVHTPTSTHEQIIRQLLNAGINVYVDKPVSENLSVVKDLYKLAEEKDLMLTCGFNRRFAPFDQVLKAIPDKRLIMSEKIREGAQQETKFAIFDLMIHSVDTALYLMDEPIKSVNNHLVTKGKYLEQGYVTLTSEHSQVQITNNLVGGVNLEQTTVQSSEQRAQVTNLNLLDTYQTGIKEQTTRPDWERNLVTRGFEPLILEFLSAVSSSGDNPISPESSILSHKICADLADSSNK
>NZ_CP019323.1|WP_076614077.1|607696_608050_-|DUF1801-domain-containing-protein
MSPIEEYIKNAPKNQQEMLNSMYYLLKNELCDANEKISYGMPTFYLDENIVHFAGMKNHLGFYPTPGPIAEFSIQLKDYKTSKGAIQFPYDQKLPEDLIKSIITFRKQEILNGKSSD
>NZ_CP019323.1|WP_076614078.1|608134_610036_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG
MQVKEFDSENYDVVVVGAGHAGSEAALASARMGQKTLLVTINLDMVAFMPCNPSVGGPAKGIVVREVDALGGEMGRNIDKTYVQMRMLNTGKGPAVRALRAQADKNMYHRMMKEVLEDEPNLTLRQGVVDKLIVEDGVCKGVVTATGARYHAKSVVLTAGTSSRGKIIIGELTYSSGPNNSIPSIKLSEDLESHGFKLTRFKTGTPPRVNEATIDFDKTEEQPGDKEPNHFSFETPDSQYLKDQMSCWMTYTNATTHAIIRENLDRAPMFSGVIKGVGPRYCPSIEDKIVRFADKPRHQIFLEPEGRDTKEYYVGDFSTSMPEEVQLKMIHSVAGLEHAKLMRPGYAIEYDVIEPWQLKLNLETKVVKNLFTAGQMNGTSGYEEAAGQGLMAGINAALRAQNKDPFILRRDEAYIGVMIDDLVTKGTNEPYRLLTSRAEYRLILRHDNADLRLTDKGYDLGLISDDRYARFNDKRDATKAELKRLNRKMITPSMAESFMEDHGFKSLKDGILADHLLRRPEVHYEDIIAMIGDPEGVPVDRRVKEQVEIAIKYAGYIKKEQMKIERLKKMESKKIPDRLDYTKVPSLATEAVQKLSKITPETIAQASRISGVNPADIGILSVYIEQGRIAKIS
>NZ_CP019323.1|WP_192844209.1|610044_611433_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE
MMPTVTEYDTIAAVSTPPGEGGISIVRLSGDQAIDIAKKIYKGKNLTKVATHTINYGHIYDPTDKSLVDEVMVSVMRAPKTFTREDVVEINTHGGIVPTNKVLQLLIGAGARMAEPGEFTKRAFLNGRIDLTEAESVMDLIRAKTDKAMQVAVNQLDGNLNHLISNLRQEILDALAQVEVNIDYPEYDTEQMTTKMLLEKAKLVGSNIDSLLKTADSGEILQHGLATAIVGKPNVGKSSLLNRLLDEDKAIVTDVAGTTRDVVEQYVNIDGVPLKLIDTAGVRDTQDKVEKIGVERSIKALNEADLVILVLDSSRELESDDIELLDATKDKRRIIIFNKNDLIPVITPKNVSQLKDDDIIIVTSAIKNDGIDTIKQTIGKIFNAGIEDSSTDVIITSARQAGLLRQAKINLNDVISGIQAGMPIDLVQIDMTSCWDTLGEITGESYPDELITQLFSQFCLGK
>NZ_CP019323.1|WP_076614080.1|611580_612423_-|membrane-protein-insertase-YidC
MNKKSLKKYLGVALLLSVVLVLAGCSNLNEPITSQSTGFWDHYILYSFSRFILWLASLVGNSYGWAIVLFTIVIRVILLPLNWFQIRSMNKQMQIQPQMKALQNKYSAKDVDTQQKLREETQKLYSEAGVNPVAGCLPLAVQMPVMFALYQAIYKTTQLRDGSFLWMQLGKADPYYIMAILAALFTFLSTYISSYSQPTQNATTKIMTYVMPIFIFVPALTFPSAITIYWVVTNAFQVLQTLAFQNPFKYRRERREKEEEEREKERKLRKAKKRVYKRRK
>NZ_CP019323.1|WP_076614081.1|612452_612794_-|ribonuclease-P-protein-component
MRKSYRIKKENEYQYVYSKGKSCANRNFVLYQMPKTGQKHFRVGLSVGKKVSHTAVGRNRIKRYVRQSLLELKPDLPAELDFLIIARKPSVDLDMFETKKNIVHLLKLGKVIG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP019323_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019323_7

840014-840112

Orphan

Consensus_repeat	Method
TGATGCAACAACAGGTGCTTCAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP019323_7

>merge|NZ_CP019323|7|840014-840112|CRISPRCasFinder
TGATGCAACAACAGGTGCTTCAAAGCATGACGACTCTGATGACTCAGAAGAACAAAGTGGCCCAACGCCTCAAGTTGATGCAACAACAGGTGCTTCAGA

>NZ_CP019323|7|7|840014-840112|CRISPRCasFinder
TGATGCAACAACAGGTGCTTCAAA	GCATGACGACTCTGATGACTCAGAAGAACAAAGTGGCCCAACGCCTCAAGT
TGATGCAACAACAGGTGCTTCAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019323.1\|WP_076614278.1\|845376_846024_+\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|380314
NZ_CP019323.1\|WP_076614266.1\|832194_834618_+\|flavocytochrome-c	unknown	unknown	gnl\|CDD\|273816
NZ_CP019323.1\|WP_076614269.1\|837033_837333_+\|DUF2316-family-protein	unknown	unknown	gnl\|CDD\|370809
NZ_CP019323.1\|WP_076614268.1\|836228_836960_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|369777
NZ_CP019323.1\|WP_076614277.1\|843840_845268_+\|C69-family-dipeptidase	unknown	unknown	gnl\|CDD\|335383
NZ_CP019323.1\|WP_076614267.1\|834839_836066_+\|OFA-family-MFS-transporter	unknown	unknown	gnl\|CDD\|340911
NZ_CP019323.1\|WP_076614281.1\|850070_850949_+\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NZ_CP019323.1\|WP_076614279.1\|846097_847330_-\|DUF389-domain-containing-protein	unknown	unknown	gnl\|CDD\|377221
NZ_CP019323.1\|WP_076614265.1\|831571_832195_+\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223508
NZ_CP019323.1\|WP_076614271.1\|838430_838994_+\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223508
NZ_CP019323.1\|WP_076614264.1\|830422_831379_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP019323.1\|WP_076614275.1\|842410_842719_+\|bacteriocin-immunity-protein	unknown	unknown	gnl\|CDD\|370205
NZ_CP019323.1\|WP_076614280.1\|847350_848529_-\|cation:proton-antiporter	unknown	unknown	gnl\|CDD\|223551
NZ_CP019323.1\|WP_120270351.1\|837390_838233_-\|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl\|CDD\|366370
NZ_CP019323.1\|WP_076614263.1\|829483_830419_+\|FAD:protein-FMN-transferase	unknown	unknown	gnl\|CDD\|224394
NZ_CP019323.1\|WP_076614273.1\|840148_841090_+\|FAD:protein-FMN-transferase	unknown	unknown	gnl\|CDD\|224394
NZ_CP019323.1\|WP_076614274.1\|841261_842245_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381305
NZ_CP019323.1\|WP_076618667.1\|848854_850084_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270451
NZ_CP019323.1\|WP_076614276.1\|842798_843380_+\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|365914
NZ_CP019323.1\|WP_076614262.1\|828389_829463_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368573

Protein	Function_ID	Function_description	E-value
NZ_CP019323.1\|WP_076614278.1\|845376_846024_+\|nitroreductase-family-protein	gnl\|CDD\|380314	cd02137, MhqN-like, nitroreductase family protein similar to the NAD(P)H nitroreductase MhqN. A diverse subfamily of the nitroreductase family containing uncharacterized proteins; includes nitroreductases MhqN, YodC, YdgI, DrgA. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.	1.29662e-43
NZ_CP019323.1\|WP_076614266.1\|832194_834618_+\|flavocytochrome-c	gnl\|CDD\|273816	TIGR01813, Fumarate_reductase_flavoprotein_subunit, flavocytochrome c. This model describes a family of redox proteins related to the succinate dehydrogenases and fumarate reductases of E. coli, mitochondria, and other well-characterized systems. A member of this family from Shewanella frigidimarina NCIMB400 is characterized as a water-soluble periplasmic protein with four heme groups, a non-covalently bound FAD, and essentially unidirectional fumarate reductase activity. At least seven distinct members of this family are found in Shewanella oneidensis, a species able to use a wide variety of pathways for respiraton. [Energy metabolism, Electron transport].	1.3457e-99
NZ_CP019323.1\|WP_076614269.1\|837033_837333_+\|DUF2316-family-protein	gnl\|CDD\|370809	pfam10078, DUF2316, Uncharacterized protein conserved in bacteria (DUF2316). Members of this family of hypothetical bacterial proteins have no known function.	1.16332e-38
NZ_CP019323.1\|WP_076614268.1\|836228_836960_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	3.84419e-28
NZ_CP019323.1\|WP_076614277.1\|843840_845268_+\|C69-family-dipeptidase	gnl\|CDD\|335383	pfam03577, Peptidase_C69, Peptidase family C69.	8.51019e-173
NZ_CP019323.1\|WP_076614267.1\|834839_836066_+\|OFA-family-MFS-transporter	gnl\|CDD\|340911	cd17353, MFS_OFA_like, Oxalate:formate antiporter (OFA) and similar proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of Oxalobacter formigenes oxalate:formate antiporter (OFA or OxlT) and similar proteins. O. formigenes, a commensal found in the gut of animals and humans, plays an important role in clearing dietary oxalate from the intestinal tract, which is carried out by OFA/OxlT, an anion transporter that facilitates the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation. This exchange generates an electrochemical proton gradient and is the source of energy for ATP synthesis in this cell. The OFA-like subfamily belongs to the Monocarboxylate transporter -like (MCT-like) family of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.71516e-102
NZ_CP019323.1\|WP_076614281.1\|850070_850949_+\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	6.51218e-56
NZ_CP019323.1\|WP_076614279.1\|846097_847330_-\|DUF389-domain-containing-protein	gnl\|CDD\|377221	pfam04087, DUF389, Domain of unknown function (DUF389). Family of hypothetical bacterial proteins with an undetermined function.	3.93482e-49
NZ_CP019323.1\|WP_076614265.1\|831571_832195_+\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|223508	COG0431, COG0431, Predicted flavoprotein [General function prediction only].	2.57509e-43
NZ_CP019323.1\|WP_076614271.1\|838430_838994_+\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|223508	COG0431, COG0431, Predicted flavoprotein [General function prediction only].	1.25165e-43
NZ_CP019323.1\|WP_076614264.1\|830422_831379_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.11091e-39
NZ_CP019323.1\|WP_076614275.1\|842410_842719_+\|bacteriocin-immunity-protein	gnl\|CDD\|370205	pfam08951, EntA_Immun, Enterocin A Immunity. Gram-positive lactobacilli produce bacteriocins to kill closely-related competitor species. To protect themselves from the bacteriocidal activity of this molecule they co-express an immunity protein (for discussion of this operon see Bacteriocin_IIc pfam10439). The immunity protein structure is a soluble, cytoplasmic, antiparallel four alpha-helical globular bundle with a fifth, more flexible and more divergent C-terminal helical hair-pin. The C-terminal hair-pin recognizes the C-terminus of the producer bacteriocin and this interaction is sufficient to dis-orient the bacteriocin within the membrane and close up the permeabilising pore that on its own the bacteriocin creates. These immunity proteins interact in the same way with other bacteriocins, family Bacteriocin_II, pfam01721. Since many enterococci can produce more than one bacteriocin it seems likely that the whole operon can be carried on transferable plasmids.	1.9619e-05
NZ_CP019323.1\|WP_076614280.1\|847350_848529_-\|cation:proton-antiporter	gnl\|CDD\|223551	COG0475, KefB, Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	2.92355e-61
NZ_CP019323.1\|WP_120270351.1\|837390_838233_-\|mechanosensitive-ion-channel-family-protein	gnl\|CDD\|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	7.87994e-39
NZ_CP019323.1\|WP_076614263.1\|829483_830419_+\|FAD:protein-FMN-transferase	gnl\|CDD\|224394	COG1477, ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism].	1.94028e-88
NZ_CP019323.1\|WP_076614273.1\|840148_841090_+\|FAD:protein-FMN-transferase	gnl\|CDD\|224394	COG1477, ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism].	1.43207e-81
NZ_CP019323.1\|WP_076614274.1\|841261_842245_-\|aldo/keto-reductase	gnl\|CDD\|381305	cd19079, AKR_EcYajO-like, Escherichia coli YajO and similar proteins. Escherichia coli YajO is the prototype of this family. It is an uncharacterized aldo/keto reductase family oxidoreductase.	0
NZ_CP019323.1\|WP_076618667.1\|848854_850084_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270451	cd14748, PBP2_UgpB, The periplasmic-binding component of ABC transport system specific for sn-glycerol-3-phosphate; possesses type 2 periplasmic binding fold. This group includes the periplasmic component of an ABC transport system specific for sn-glycerol-3-phosphate (G3P) and closely related proteins from archaea and bacteria. Under phophate starvation conditions, Escherichia coli can utilize G3P as phosphate source when exclusively imported by an ATP-binding cassette (ABC) transporter composed of the periplasmic binding protein, UgpB, the transmembrane subunits, UgpA and UgpE, and a homodimer of the nucleotide binding subunit, UgpC. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.17151e-79
NZ_CP019323.1\|WP_076614276.1\|842798_843380_+\|peptidylprolyl-isomerase	gnl\|CDD\|365914	pfam00160, Pro_isomerase, Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD. The peptidyl-prolyl cis-trans isomerases, also known as cyclophilins, share this domain of about 109 amino acids. Cyclophilins have been found in all organisms studied so far and catalyze peptidyl-prolyl isomerisation during which the peptide bond preceding proline (the peptidyl-prolyl bond) is stabilized in the cis conformation. Mammalian cyclophilin A (CypA) is a major cellular target for the immunosuppressive drug cyclosporin A (CsA). Other roles for cyclophilins may include chaperone and cell signalling function.	3.0232e-66
NZ_CP019323.1\|WP_076614262.1\|828389_829463_+\|hypothetical-protein	gnl\|CDD\|368573	pfam05708, Peptidase_C92, Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family. Amidase_YiiX is a family of permuted papain-like amidases. It has amidase specificity for the amide bond between a lipid and an amino acid (or peptide). From the structure, a tetramer, each monomer is made up of a layered alpha-beta fold with a central, 6-stranded, antiparallel beta-sheet that is protected by helices on either side. The catalytic Cys154 in UniProtKB:Q74NK7, Structure 3kw0, is located on the N-terminus of helix alphaF. The two additional helices located above Cys154 contribute to the formation of the active site, where the lysine ligand is bound.	1.35499e-06

>NZ_CP019323.1|WP_076614271.1|838430_838994_+|NAD(P)H-dependent-oxidoreductase
MKIEAIVGSNKKLSYNRKLLQFISKHFTDDEIHINEIKDIPMFNENYPTGNDDNYDPELITELAKRLTEADAIIIGCPEYNHSVPSALKSVIEWLSYRIHPLSGKPVMIVGASIHPQGSSRSQTHLREILDSPGVNAEVFPGNEFFLGTAKKSFDENGDLINPGTVAFLEKCFSGFRLYSEEIHKFK
>NZ_CP019323.1|WP_120270351.1|837390_838233_-|mechanosensitive-ion-channel-family-protein
MQLTVNLNKFIKNLLFKFDWESLAQHVISVITQLILLTLVLLLINWIGKKIIRHLFKSNLNLSKSPISQNKMNTIYTIVLNIFKYILLFFWIYAILSAIGIPVGTLIAGAGIFSLAIGLGAQGFVSDMVNGFFILLEQQISVGDYININGIEGTVTYVGIRTTQLKSVDGTLNFIPNRNITVVSNLSRNDMRALIEIPVSSDSPFDNIKQVIEHVDKGLDLKSLKITQKPSILGFSNLNDGTLVIQIVAFTKHGEQFNVKNVLMKKYLTALNSAGINLPK
>NZ_CP019323.1|WP_076614269.1|837033_837333_+|DUF2316-family-protein
MSLTNEQRVSTVREFHENLEISGLTFTQMADDLGTTAKVIEDILNLNVEKIEDPWILRNYLIKKIISLNKEPVPFTALAGDYHDYWFLNSKLIDKEKVV
>NZ_CP019323.1|WP_076614268.1|836228_836960_+|class-I-SAM-dependent-methyltransferase
MNNIYDNDKFFEKYSKMNRSINGLSGAGEWSTLKPMLPDFTNKDVLDLGCGYGWIDRYAVENNARSVLGVDLSEKMLAVAKEKTETDKIDYIKGDISQIDFEDNRFDIVISSLALHYVESFSYLIKKISKYLKPNGILIFSVEHPIFTAQGSEEWNYDENGNIKDFPVDNYFKEGKRETDFLGETVVKYHKTLTTYLDGLLTSGFRLNRVVEPMPPKNMMDIPGMKDELRRPMMLIISATNIK
>NZ_CP019323.1|WP_076614267.1|834839_836066_+|OFA-family-MFS-transporter
MTKEINRWQVLIASTAILLCTGAVYAFSVFAGPLSADKGWSMAEIMLAFTINSAISPIPMILGGFLTDKHLAKWTIIVGGLMFGLGFFLTGLVTSPSMLYLTYGLIGGLGQGLAYSGCLSNTIKLFPDKKGLASGIITAGMGGAAIIAAPIANSFIQSHDALYAFRMLGIFYMIVVAIASFFIKEAPVGFKPAGFNPPERHGKGLPNKNWIAMLKTPYFYLIFLMLFTGAFSGLMIASNAAVIGQQMFKLTAGTAALYVSLYSLSNCAGRVVWGSVSDKVGRNNALNIILGVIVLAFIVLVTVSSQAGFAIGIIVLGLCFGGVMGVFPPLVIENYGPLNQGVNYGIIFCGYSGAAFFGPKVAANMAAANGGDFSKAFYVAIAVALVGLVLNIIYIQLKKRESAEAVTA
>NZ_CP019323.1|WP_076614266.1|832194_834618_+|flavocytochrome-c
MKFIGIVGTNAEKSYNRMLLQFMKQHFSDKAEIEILELFDVPMFDESDDQSNSEIIQEFNTKISDADGVIIATPEHNHSVPSALNSIIEWLSFNLHPFDGKPVMIVGASLHPQGSSRAQLHLRQILDAPGVNAAVMPGSEFLLGQAKDAFDDNGNLKSEGTIDFLDSCFTKFKRFTEIANLLNVPEDLNFKPGTFEVTAKGHNGDLPMSVTLSDDRIEDIDIDTSKETKGIADVVFTKIPQEIVDGQTLNVDVISGASITSHGVIDGVAKAVKMAGGNPEILKKRPKASNIVRNDEEYTTDVVVVGAGGAGLTAAAKILDEGKSVIIAEKFPSPGGNTVRAGGPMNAADPTWQNKFDANAGEAHRLKEIKDMKLDDIDPEYRDDFKELQKQIGQYLDSKGNYLFDSKLLFRIQTYLGGKRTDLQGNEIHGQYDLVKILTDHALESVKWLEKVGVEFDKNEVTMPVGALWRRGHKPMGPEGFAYIKALKKYVEDNGGKLMTETPVKELIIENGEVKGVIARGNSGQKITIHANSVILASGGYGANTKMLKKYNTYWTEIDDDIKTSNSPAITGDGIKLGLSAGADLVGMGFTQMMPVSDPDTGEIFTGLQVPPANFIMVNQSGKRFVNEYGSRDQLTQAAIDNGNLFYLIADDEIKKTAYNTSQEKIDNQVKAGTLYRDDTLTGLAKQLKIDPEVFVDTITKYNSYVDAGNDPEFGKDAFDLKVVKAPFYATPRKPAIHHTMGGLKIDPETHVLNKDGQIINGLYAAGEVAGGLHAGNRLGGNSLADIFTFGRIAGKESINQRVEQSE
>NZ_CP019323.1|WP_076614265.1|831571_832195_+|NAD(P)H-dependent-oxidoreductase
MKFIGIVGTNATKSTNRQLLQFMQKHFSKKADLEVCEIKGLPAFNQPQDRVLPTGLKDLSDKIEESDGVIIATPEYDHTVPAPLKSVLEWLSYTTRPFIDKPVMIVGASYGALGSSRAQNHLRQILDAPELKARVMPSEEFLLGHSLQAFDESGDLIYKDKATELEECFDQFLLFVDITNQLVKNHGFQAEQNKEFTWEKATEGGNN
>NZ_CP019323.1|WP_076614264.1|830422_831379_-|LysR-family-transcriptional-regulator
MPMIDSPNMLQYLDTLLKYGNYTKAAKSLYISQPYLTQTIKKVEKELDIEIINRHDTPLQLTEAGRIYYQYLNSMEVKQDNFRKQISKYASTEHTIIRIGVLSSLGTYLLPLFLPTYLKSHPNVKIELYEAIPDINEKKTLNGDLDFFIGQNPETISPRLTVYDQGKHGYYAIIPESSKLYQPKEKFLKPGSISIKSLLQENLILTTHGSAIRRQVDYLIHKFKIQPNIVLESNNIFTIVALATNNLGVTFLPESVPIPKANDNINIYKLPMDLISLNYFIAHPADKTLIAAETELVDSFLHYLKFDIEVKNASPMIS
>NZ_CP019323.1|WP_076614263.1|829483_830419_+|FAD:protein-FMN-transferase
METAEKKLHLMGTIIIVWVKAKNPQDLLDMAEKKLIDYESRFSANAKSHLTNINDNAGIRPVKIESDLFELIKIGKEQSLIRNSALNIAIGPLIQAWRIGFNDARYPGQARINELLKLIDPADIILDETNQTIFLKHKQMSLDLGAIAKGYFADKIINYFKSQQASAGFISLGGNVLTFGDEPDHLDGMWRIGVQNPFLPRGNFVATLKVLDKSVVTSGIYERKFVFKGHTYHHIFDTSTGYPIKTNLESITIVADKSIDCEIWTTRLFGQNALKAVEILNKLDGIDGVVVTTDGQMAYSDGLKKKITLVQ
>NZ_CP019323.1|WP_076614262.1|828389_829463_+|hypothetical-protein
MNDLLHNYRMSRTMGIVVLLGLFMFGTLPIMIIAYCYLALVLIIHTWVKIGFSKKVKSSLTVIYGFMLAFQITFVTLTVFPMHNINLLYYPAKIFAVVLFSIPFLVERFITVSNGAEFYMPTVESVTAISFEELRDNTKRIRSMMQSVSNMNQKISIDHVKTVLEDIPRHSSVRYINQGTLTQYYFDAAKKSLDDEHMYLVVSNTGSPASEIISAFTQKQFNHVSLSFDRALDTIISYNGGDNIYPPGMNAETLEFFHQKSDASVLIYSLPATVEQKQFLIDKIAEINHNGSAYNLLGLVAKHSYKPNIMFCSQFVYKMLKLAGLEFFDKKDGEVRPTDFIELDYYKKLDFEYEITF
>NZ_CP019323.1|WP_076614273.1|840148_841090_+|FAD:protein-FMN-transferase
MIDNLIQHRIHKTGYALGTNISLTTFGTLNSFGVDEAFKLIQRYEDLLTVNRGHSEMMSVNKSAGLDPVQVSNATYSLVKTAMKYSRQNFGFNAAIGPLVKLWKIGFVGANIPSDDDIKKRMRLIDPSDVELDDVKQSVFLHKSGMELDLGGIAKGYIADRIRDLWHSLGIDRGIIDLGGNVLFVGDSPNQANHKWIVGVQDPTSKRGETIENIQIGECSAVTSGIYERFLEIDGKKYHHVIDPRTGYPLKTDLAAVTVFVKNSIEGELEAKRLFFNNGPIPNWGADNDDLYGAVLVYQDGHFTTLKSVTERE
>NZ_CP019323.1|WP_076614274.1|841261_842245_-|aldo/keto-reductase
MEYTKLGNTGLDVSRICLGTMGFGTPGKGQFPWSIGQEDSKKIVEHALDLGINFFDTANTYSNGMSEHHLGNALKDKNRDELVVATKVFFDSSDKPNMSGLSRKAILSQIDRSLARLQMDYVDLYIIHRWDFNTPIEETMCALNDVVKSGKARYIGASAMYSWQFEKANAIAKANGFAQFVSMQDHLNLLYREEEREMLPLCEEENIAVTPYSPLASGRLARDWTASTKRAETDNIAKAKYDNTEAQDKIIVDRVGEIAQKHNVDRVQIALAWLLQKKQVVAPIVGATKSNHLDGAVKALDVTLTDEDIELLESPYLPHKLMGARTY
>NZ_CP019323.1|WP_076614275.1|842410_842719_+|bacteriocin-immunity-protein
MKTRDEKVQTMMDQISTAYSDSQVKKSPEAMELLFNSAKELDKTNDYSLVATKLCKKITYYSFEHPKDGLNALIVLYHQIKGYATKYDGIALAAMMLPVWFG
>NZ_CP019323.1|WP_076614276.1|842798_843380_+|peptidylprolyl-isomerase
MYPQLDLENAKGTKITIKTNHGDIDIQLFDELVPKTVKNFVELAKKDYYNGVVFHRVIPDFMIQGGDPTGTGMGGESIYGDAFEDEFSDQLFNLDGALSMANAGPNTNGSQFFIVTNQNMPKRMIKQMAPAGYPEEIIAEYKNGGTPWLDHRHTVFGQVTDGMDVVREIAKVKRDRNDKPDEDVIIESVTERE
>NZ_CP019323.1|WP_076614277.1|843840_845268_+|C69-family-dipeptidase
MKNTSSDCTEILVGKGASMDGSTIVARNEDGYGPINPIKFVVHEAKDQKDAFYNSVTTGVKVPLPDHAYRYTATPQADQSDGQYEEAGINEYNVGMSSTETTETNARVLGYDPLVTDGVDEEAMLTLVLPYIKTAKEGAIRLGALLEKYGTGECNSIAFNDKDEIWLLETAGGHHWAAMRLPEDTYAIVPNQTVVQDIDVSDTDNFLVATDLVDFVAKHHLNPQPDKFNFREIFGTHSEEDAYYNTPRTWYGQKLFNPEIEQEPTDQNMTLAKKPSKKIAIEDVQYFLSSHYNGTKYDPFGTFASGTKEEQRQFRSIAMDRNQASSILQIRSDVDKNHAAVQWLSLGFFAYSPYVPFYTNITDTPEDYKNTTNNVDVNNVYWLEKTLSVMIEPHYHEYSDMIHAYLKGCQSFARQRLEATDVSLDNVNDNVTDVLTKSNIKTAAEISSRTHKLFDGIVKKGLTLSKTTWEKGQNL
>NZ_CP019323.1|WP_076614278.1|845376_846024_+|nitroreductase-family-protein
MDATKKLVNNDFSDIMLNRHSYRKFKSGVSIPREEISEMLKEATSAPSACNLQSWHFVVCDNKEGKDKAHSVMMPFNYEQTDTSSAVIFVLGDTQSHYKYRDVWNKACDNGQITPEMRDKVFKTFLPLYENADRSFLEKDATIDGSMIAMQLLLIARAHGYEANPMSGYAFDKVAETFDLDKERFIPVTAIAIGKPDGEFTKSVRYAVDEVTDFI
>NZ_CP019323.1|WP_076614279.1|846097_847330_-|DUF389-domain-containing-protein
MNQQSEEESELRIDTIDSSVREDLKLDWSNFAILFCSIIIASVGLNMDSSPVIIGAMLISPIMAPITGIGYSIGSGYTGLLKKSARLFAIELLIGIVASSIYFTLSPMKEASEQLMNRTSPTLWDVLIAFFGGIAGIIAASKKTPGNILPGVAIATALMPPLCTVGYGISQTNWQIIGGAAYLFLINAFFIALSALLGTIIFRLQSGQKLDIPLKNRVFTIVLAVIIIIPSMISASTIVKQSYVEAQLDQFVTGELSSVYVTKKDVSNNKITLSIIGNSISKTRLKSLKNDLDEYHLGGYSLKINQLTNGDYITTDAFNKYVKEQSSVKSSSSSETSLDKLQDKLMSSKYSDDIKDVYVGNMQDSKDEKHKVVVVKLTDTGKNDKDTLDKGIQKLVKKTISDSDVTVIYN
>NZ_CP019323.1|WP_076614280.1|847350_848529_-|cation:proton-antiporter
MGFLGILVLILITTTIVGHYSSRMGIPAVIGQLLVGIILGPAILNWVKPTEFIHIFSEMGVIILMFIAGIESDLQLLKKYLKPSFLVAILGVIVPVALTYGVSLLFNLGVKESLFISVIFAATSVSISVAVLKELDVLNGKAGATILGAAVVDDILAVIILSVMVSLMGEGVKGSSSGTNLILTFTEQILFFIAIYFVVKFLAPYMARIGEKLFIPVGPTIMAMILCFGMAYLADLIGLSSVVGAFFAGIAISQTRVLEEVDHSIEPIGYAIFIPVFFVSIGLNMSLSGIENDLWFIIALTIVAILSKLFGAGLGAHLSHFTFAESYMVGAGMVSRGEMALIIAQIGYQSKLISSDYYSAIISAIILTTLLAPFLLKHAAKLSPQIPKDLNR
>NZ_CP019323.1|WP_076618667.1|848854_850084_+|ABC-transporter-substrate-binding-protein
MMVIFAGCSSTSKTSAKSVTHITYWHVNAQTQGGSTVDKLVEEFNKTHKNIKVTAKYNPNMYQGLMQNLQSAQASGKVPDVVQVGWAYDNYFSSNFKYMTPTDAAKKFDGNDKFINNHFTTKTLSFAKDANKKLVGLPYSLSTPVLFVNNDLLKQYNIDVKSLDTWEGVQSAAKVIKDQGGKYGLYIQEPGDTWAQQALMLSNGAKIQKNGKAAFASSNGTGAYKLYQEMVTDKTALHTPWAQGMDSFVKGDVAMAFTTIAQASHIKKGASFNASAIIAPHFKNHKTVVPAGGSMLAITAQDSAQQKAAWEFEKFMFKASSSVTWSKGTGYLPPTKDALDSKEFKDYVSENPMLVPAVKTLDKAIPWTSFPKNGLQAEQAMVDARDKILSGSDVSSTLKAAQDKINAQQ
>NZ_CP019323.1|WP_076614281.1|850070_850949_+|sugar-ABC-transporter-permease
MHNNKKFLPFIYLLPTGILLTIFMIIPIIYTFYLSFFDWNLIAPTKDFVGMKNYIEVFTDPVNQKVLLNTFFYIVLLLVLNFIIPYVISLIVKFFIKRMQGVYKIIFFIPSLFSLVVGAMIFSWLLNPVSGPVAFLFRQSGFVLPNWTNSGGLAIVVICLITNWKVFGYNFILLLTGLGSIPKNIIDASTVDRIPKWRMIWNVILPMNRSIAIYVLILTIVQGLQYAFTPINVITTGGPYYGSSNVLYHTYLNAFVLYRTGSASALAITTFIIFLVLLYLEIRFVEGRSRYE

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP019323_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019323_8

923742-923874

Orphan

Consensus_repeat	Method
GAAGAAATTGTGAATTGTATCGCGTTTCAGCAAGTTTGAGGATAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP019323_8

>merge|NZ_CP019323|8|923742-923874|CRISPRCasFinder
GAAGAAATTGTGAATTGTATCGCGTTTCAGCAAGTTTGAGGATAAAAAAGAAAAGAACAAATTTTTTTACCTGAAAAAATCAAGAAGAGAAGAAATTGTGAATTGTATCGCGTTTCAGCAAGTTTGAGGATAA

>NZ_CP019323|8|8|923742-923874|CRISPRCasFinder
GAAGAAATTGTGAATTGTATCGCGTTTCAGCAAGTTTGAGGATAA	AAAAGAAAAGAACAAATTTTTTTACCTGAAAAAATCAAGAAGA
GAAGAAATTGTGAATTGTATCGCGTTTCAGCAAGTTTGAGGATAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019323.1\|WP_076614354.1\|927732_928002_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076614343.1\|918637_918997_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|377579
NZ_CP019323.1\|WP_076614340.1\|915337_916066_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224041
NZ_CP019323.1\|WP_076614350.1\|925014_925287_-\|metal-sensing-transcriptional-repressor	unknown	unknown	gnl\|CDD\|197390
NZ_CP019323.1\|WP_076614353.1\|927195_927618_+\|arsenate-reductase-(thioredoxin)	unknown	unknown	gnl\|CDD\|131738
NZ_CP019323.1\|WP_076614357.1\|930349_931705_+\|PTS-sugar-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|224372
NZ_CP019323.1\|WP_076614342.1\|916891_918400_-\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|341249
NZ_CP019323.1\|WP_076614344.1\|919363_920749_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP019323.1\|WP_076614349.1\|924036_924870_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|236841
NZ_CP019323.1\|WP_157886437.1\|931728_931902_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076614346.1\|921561_922020_-\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|223806
NZ_CP019323.1\|WP_076614347.1\|922238_922928_+\|VIT-family-protein	unknown	unknown	gnl\|CDD\|153123
NZ_CP019323.1\|WP_076614351.1\|925457_925781_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP019323.1\|WP_076614352.1\|926027_927056_-\|LCP-family-protein	unknown	unknown	gnl\|CDD\|181811
NZ_CP019323.1\|WP_076614345.1\|920738_921437_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP019323.1\|WP_076614348.1\|922944_923646_+\|VIT-family-protein	unknown	unknown	gnl\|CDD\|153123
NZ_CP019323.1\|WP_076614355.1\|928049_928775_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_CP019323.1\|WP_076614341.1\|916066_916888_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|183100
NZ_CP019323.1\|WP_083685916.1\|918983_919274_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|376540
NZ_CP019323.1\|WP_076614356.1\|928944_930324_+\|glycoside-hydrolase-family-1-protein	unknown	unknown	gnl\|CDD\|225343

Protein	Function_ID	Function_description	E-value
NZ_CP019323.1\|WP_076614343.1\|918637_918997_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|377579	pfam05973, Gp49, Phage derived protein Gp49-like (DUF891). This family consists of hypothetical bacterial proteins of unknown function as well as phage Gp49 proteins.	1.81268e-16
NZ_CP019323.1\|WP_076614340.1\|915337_916066_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	5.7553e-102
NZ_CP019323.1\|WP_076614350.1\|925014_925287_-\|metal-sensing-transcriptional-repressor	gnl\|CDD\|197390	cd10155, BsYrkD-like_DUF156, Uncharacterized protein YrkD from Bacillus subtilis and related domains; this domain superfamily was previously known as part of DUF156. This domain family contains an uncharacterized protein YrkD from Bacillus subtilis and related proteins. This family is part of a larger superfamily that contains various transcriptional regulators that respond to different stressors such as Cu(I), Ni(I), sulfite, and formaldehyde, and includes CsoRs (copper-sensitive operon repressors). CsoRs form homotetramers (dimer of dimers). In Mycobacterium tuberculosis CsoR, within each dimer, two Cys residues on opposite subunits, along with a His residue, bind the Cu(I) ion (forming a triagonal S2N coordination complex, C-H-C). These residues are conserved in the majority of members of this superfamily. In this family, however, not all these residues are conserved, there is an Asn instead of the His (C-N-C); also a conserved Tyr and a Glu residue that facilitates allosteric regulation of DNA binding for CsoRs are very poorly conserved.	4.33268e-20
NZ_CP019323.1\|WP_076614353.1\|927195_927618_+\|arsenate-reductase-(thioredoxin)	gnl\|CDD\|131738	TIGR02691, Protein_ArsC, arsenate reductase (thioredoxin). This family describes the well-studied thioredoxin-dependent arsenate reductase of Staphylococcus aureaus plasmid pI258 and other mechanistically similar arsenate reductases. The mechanism involves an intramolecular disulfide bond cascade, and aligned members of this family have four absolutely conserved Cys residues. This group of arsenate reductases belongs to the low-molecular weight protein-tyrosine phosphatase family (pfam01451), as does a group of glutathione/glutaredoxin type arsenate reductases (TIGR02689). At least two other, non-homologous groups of arsenate reductases involved in arsenical resistance are also known. This enzyme reduces arsenate to arsenite, which may be more toxic but which is more easily exported. [Cellular processes, Detoxification].	3.80205e-76
NZ_CP019323.1\|WP_076614357.1\|930349_931705_+\|PTS-sugar-transporter-subunit-IIC	gnl\|CDD\|224372	COG1455, CelB, Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism].	5.65519e-120
NZ_CP019323.1\|WP_076614342.1\|916891_918400_-\|AMP-binding-protein	gnl\|CDD\|341249	cd05926, FACL_fum10p_like, Subfamily of fatty acid CoA ligase (FACL) similar to Fum10p of Gibberella moniliformis. FACL catalyzes the formation of fatty acyl-CoA in a two-step reaction: the formation of a fatty acyl-AMP molecule as an intermediate, followed by the formation of a fatty acyl-CoA. This is a required step before free fatty acids can participate in most catabolic and anabolic reactions. Fum10p is a fatty acid CoA ligase involved in the synthesis of fumonisin, a polyketide mycotoxin, in Gibberella moniliformis.	2.10682e-135
NZ_CP019323.1\|WP_076614344.1\|919363_920749_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	4.89951e-52
NZ_CP019323.1\|WP_076614349.1\|924036_924870_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|236841	PRK11088, rrmA, 23S rRNA methyltransferase A; Provisional.	6.59837e-37
NZ_CP019323.1\|WP_076614346.1\|921561_922020_-\|transcriptional-repressor	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	4.45716e-40
NZ_CP019323.1\|WP_076614347.1\|922238_922928_+\|VIT-family-protein	gnl\|CDD\|153123	cd02432, Nodulin-21_like_1, Nodulin-21 and CCC1-related protein family. Nodulin-21_like_1: This is a family of proteins closely related to nodulin-21, a plant nodule-specific protein that may be involved in symbiotic nitrogen fixation. This family is also related to CCC1, a yeast vacuole transmembrane protein that functions as an iron and manganese transporter. .	4.16462e-92
NZ_CP019323.1\|WP_076614351.1\|925457_925781_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	1.48855e-32
NZ_CP019323.1\|WP_076614352.1\|926027_927056_-\|LCP-family-protein	gnl\|CDD\|181811	PRK09379, PRK09379, LytR family transcriptional regulator.	2.28704e-77
NZ_CP019323.1\|WP_076614345.1\|920738_921437_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	5.0235e-81
NZ_CP019323.1\|WP_076614348.1\|922944_923646_+\|VIT-family-protein	gnl\|CDD\|153123	cd02432, Nodulin-21_like_1, Nodulin-21 and CCC1-related protein family. Nodulin-21_like_1: This is a family of proteins closely related to nodulin-21, a plant nodule-specific protein that may be involved in symbiotic nitrogen fixation. This family is also related to CCC1, a yeast vacuole transmembrane protein that functions as an iron and manganese transporter. .	5.66702e-99
NZ_CP019323.1\|WP_076614355.1\|928049_928775_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	2.75965e-58
NZ_CP019323.1\|WP_076614341.1\|916066_916888_-\|ABC-transporter-permease-subunit	gnl\|CDD\|183100	PRK11365, ssuC, aliphatic sulfonate ABC transporter permease SsuC.	6.76449e-100
NZ_CP019323.1\|WP_083685916.1\|918983_919274_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|376540	pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within Neisseria gonorrhoeae NGO_0477, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteristic of the whole family.	5.09469e-10
NZ_CP019323.1\|WP_076614356.1\|928944_930324_+\|glycoside-hydrolase-family-1-protein	gnl\|CDD\|225343	COG2723, BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase [Carbohydrate transport and metabolism].	3.91045e-173

>NZ_CP019323.1|WP_076614348.1|922944_923646_+|VIT-family-protein
MKAVNVAKSKKQKKTMAERSNTLRAGVLGSNDGILTVVGVLFSVAVATTNQFTIFIAGLSDLLACAFSMASGEYASVSSQKDTEKAAIEKERELIKTDFAGEVQAVADFYVKRGVTENTSKEIAEELMKKNALATVVKVKYDLDLGHYMSPWDAAFSSLVAASSGGIFPLVAMTLLPVSLQWPGTILAVTLSVALTGFLSAKLGDGLVKTAIIRNVIVGIITMIIHYSVGLML
>NZ_CP019323.1|WP_076614347.1|922238_922928_+|VIT-family-protein
MQKKKKNRSLAEKINVMRASVMGANDGIVSVAGIVIGVAGARSSNYAIFLAGIAGMLAGTISMAMGEWVSVSTQRDSERRAIEKESAALDGNYDREFEFIKNKYQSTGISSDLALKATKEMMSDDSLDVAVRERYGFNPKEHTSAIAAALASMISFPTGSILPLLSITLFPSNIKIVATVVAVIIALTVTGYTAAALGNANRLKAVFRNVLSGLLTMLVTYLIGSLFAH
>NZ_CP019323.1|WP_076614346.1|921561_922020_-|transcriptional-repressor
MANSSVMEDTLKVLKEHKLRVTPQRHIILAYLASHHNHPTVETIRSGLSKDLPNMGSSTIYNTLNTFVEHHLVVELQNGDGSTHYDYFGTPHYHAICTNCGKIVDVSYPGFSKDEKALEEKTADISGYMISGNHMEVYGLCPECQVKLGIKK
>NZ_CP019323.1|WP_076614345.1|920738_921437_-|response-regulator-transcription-factor
MKNTILIVEDELSLSSYLTKELQFEDFNVVVANDGLEAMEKYEEHQNELLLILLDWMLPKLDGMEVLRRIRKHDQVPVIIMTARDYVGDKVAGLDNGADDYITKPFEIEELLARVRVIQRRAEQLSEPDQTYQIADLTLNTKSHQVVRNNVNIQLTRREYDLLLFFLQHVNQVFTRDELLDNVWGEDFLGQQNVVDVYVGYLRSKIDGKNDRPLIQTIRGVGYSIEDTANED
>NZ_CP019323.1|WP_076614344.1|919363_920749_-|HAMP-domain-containing-histidine-kinase
MKTKNVTTYEKLINQGINRLVVIITLSISLLILAFVGVQQTMMTTRDAQGLMMSLNRSNIESIPNFIEWNNANERHTKQNSFIRVKTQDKSVTAASLKRQSVIMTSPSSKRFLARKKLHIFFNKNMVYIPGYGLFLYYTQKNNNTTYQLWVSLNNLLRSLLLLLIVIAFVVFVTLGFGTWWARRLAKSLSAPTLELVNETKKTTQDLETNQPSLTVPDSPLEINELGNSFNDLLNVQNQRLEREKQFVSDSSHELRTPIAAIRGNISLIKRRGDKHPEVIPESLDFIDEESLRMQKLIENLLHLSRADKADVELSEVNLSETIKQLSDHYQASIPQNINVSIEPDLVINGNLDLIQQITIALLDNASKYSPKNGHIDVNVSKDNDNINLSIADNGMGIPDDKKDKIFQRFYRVDESHSTQIKGSGLGLAIVAKLVILNNAQIIVSDNKPNGSIFTVTFKKA
>NZ_CP019323.1|WP_083685916.1|918983_919274_+|helix-turn-helix-transcriptional-regulator
MTKVELINAAEYIENEKRKNPELSRMMDIEENKMELAINISKLRRSLGYSQEEFAKKVNKPQSTIARIESGEGNPTMKTIFEIGYAVGKKVNISYE
>NZ_CP019323.1|WP_076614343.1|918637_918997_+|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MKKVEFVFLVLDGKSEIMEFINGLPVKDRSKLYDTINIISEFGIPIAARQEWVKKLDSDIYEIRSKVGTNIQRCLYFHKYKNIYVITNGFTKKTDRTPQREIRRARLLMNRSKSQDDKS
>NZ_CP019323.1|WP_076614342.1|916891_918400_-|AMP-binding-protein
MSKLTNQLKQQLTNNPNRPIMQDAQKNWYTGSVLNKERETWLNYWSTQGIGYNDIVLVALTNSVTYSLVVQSLWEIGAIVHPINPAVTEIQINELEEQYNYSAMIMNSDMDEPDTLNDTFEKRPKLTTLHEPEVELYIRKTHESHLAKEPFDNQFAIIMHTSGTTGKPKRVGLTHNQLLANADNIIVSEELTDYDRTMIVMPLFHVNAMVISNLATRLSDGQLLFRPKFSAHLFWKEVFDEQLTWVSLTPAIIEILLQRDEQPKPNKLRFLRTASAPLLPSTHEEFKIRFDIPLIESYGMTEAASQITQNPLNATKQNSVGIPYGTDVLIVDSDYKELKTNAIGEIALKGDSVIDHYLDAQPETFSNGYLLTGDLGKIDDDGYLYIVGRRKEMIIRGGENVNPLAVEDCLTVLPFIKEMAVVGTSDKIYGEAVTAVIITNEEQTDHRYQLALLKNLANNQLMPAERPTQYIFGQELPKNATGKIQRTLLAKEIEEKQYVKEA
>NZ_CP019323.1|WP_076614341.1|916066_916888_-|ABC-transporter-permease-subunit
MQKSIDLNTSNSNPARHFSFPTQKLLPFIIPVTLVVVWQLASSVGWLSTSVLPSPIAVLQDGITLTASGELPKNLSISLYRATLGLLIGGGIGFILGFVNGMSKTFSLLFDSSIQMFRNIPHLALIPLIIIWLGINESAKISLVAIGTMFPVYINTYSGIRSVDNDLIEMGKSYELSRFDMFKKIIFPAALPQILVGVRYALGVMWTTLIVAETISASSGIGYMANNAEDFVDMETVVLCIVVYAILGKISDLVAKSFESLLLEWQTTGRNNI
>NZ_CP019323.1|WP_076614340.1|915337_916066_-|ABC-transporter-ATP-binding-protein
MKTNTMIKVNNIGKTYNNQIALQSVNLDIHNGEFVALVGMSGGGKSTLLRLIAGLEKPTSGSIDIDKTKSKSLVRMMFQEDRLLPWMTVIENLSFKSKKPEDIKHAKELLDLVELNDYADHYPNQLSGGQKQRVALARALMTDPEILLLDEPLGALDALTRRKMQDLILDICKKQNLTTVLVTHDVDEAARMADHIVVMKDSTNYFETDGPKDIRNPGQVGLVAEKVLDAILEEKPHVMKTA
>NZ_CP019323.1|WP_076614349.1|924036_924870_+|methyltransferase-domain-containing-protein
MNKDKLKRFLNSQGFFKCPNCGEKLSLNNTSLVCANNHNFDISKYGYVNFLLNMKQQKNYDKDNFENRGLILKDGLYDHILNNLTNIISNLPIETILDTGCGEGYYSREIHKSLDKQMLAFDISKDSIQQAAKNDQGNSVKWFVGDLAQLPIQDSSVDCILDIFSPANYSEFHRILKDKGYLIKVIPGENHVIELRKQASEFLRSDSYSNQRVREYFEEHFDVVDEINATKTYDVSKEVRDAFIQMTPLLFNVDKTKVNWEEIDQITVDSKILIGKA
>NZ_CP019323.1|WP_076614350.1|925014_925287_-|metal-sensing-transcriptional-repressor
MSQTIEEEQASKKITSQLKRSRGQLDGILKMMEDNRSCDDVLVQLSAVKSGVDKAMKLVIAQNIRKNVNCVDEQQLKDLQGSLDLMMKTK
>NZ_CP019323.1|WP_076614351.1|925457_925781_+|thioredoxin-family-protein
MSNIKEISDATYNDQTNTGLVITDFNADWCPPCKMMNPILEKLSSKDELGDKIKFTSMNVDHNPQTPDNFGIQGIPTFIIKKDGNVVGRLVGYQPEEKFRAALAQYM
>NZ_CP019323.1|WP_076614352.1|926027_927056_-|LCP-family-protein
MKIFKRIVIVIVALLAVIAVALGIYIYQGKKALDSVDSNSTSVSDKINTGKPISILLLGADTGADGRIDRGNSDTMMIITLNPKTHKSVMYSIPRDTMAEIVGAGKKQKNVQKINAAYNIGKSDMAKKTVSKLLGIPVDYSVAINMGALEKAVNFVGGVTVTTPIKVSYDGITIPKGTHHLNGKQALSYVRMRYQDPRGDYGRQIRQQQVLKAVTKKLEQPKYLVKLPDLITKLGPDVDSDLTDSQMEKFPIKYHSAGKKLTTKQLQGQSAWINGSSYQILPTEVMQSASDKLRANLGLSKKTLNNTETKLNKLNSAYFKDPDNTDYDTNGLDTTYYTDNTF
>NZ_CP019323.1|WP_076614353.1|927195_927618_+|arsenate-reductase-(thioredoxin)
MKKIYFICTGNSCRSQMAEGFAKKYLPDWEVRSAGVEVHGLNPKAVEVMAEKGIDISHNTSDLIDPEYFNKCDFVVTLCGDARDRCPRVPSGVTHLHWGLNDPAKASGSDVDILNVFREVRDKLEHKVDCFSKNTHNIGN
>NZ_CP019323.1|WP_076614354.1|927732_928002_+|hypothetical-protein
MTDSKIMRSIKKYVDSLEVKVTFSEPTNFNPIKYPQLEEMGQWSHDRVRNTLTLQTKHLIDYNEGDLVDALTDSRVDPYKYAIESRTFA
>NZ_CP019323.1|WP_076614355.1|928049_928775_-|GntR-family-transcriptional-regulator
MAYKYKEVANKLRDQIKAGKYVPGELLPDQNNLAKSFNTTRITVHKAIQLLVVEGMVYSKRGSGTFVRKDYASDEESTNYGSVSPIDKPLGATHTNQGKKVTSKVLELSARMPSASEANKLIIQPTDPVYVIRRVRYVNKEIFAYENTIMPTKITTITKEVLHGSVYAHLQEEGLNIEGSHRVISAEKATQIDLDTGIANELGEPIMVINQLSYLDDGQPFEISETHFPYEKSHITADITL
>NZ_CP019323.1|WP_076614356.1|928944_930324_+|glycoside-hydrolase-family-1-protein
MTKQLPKDFAWGNSTSSMQTEGAWNIGGKGKSVYDDRPATENSSDWHDAIDEYHRYEEDFDLMAKQGMNFYRFQISWSRVNPDGDGEFNEEGIEFYSKLIDALLARNITPMICLYHFDMPLHLAQEYNGFLSRHVVDAFVKYGAEMVKRFGDRVKYWITFNEQNLYHMGEAFRIAGYLEGDKTDDELYQISHHVMLAHAGVANYIHDNTDCLIGGMLAYSEVYPATSDPKDVLYARQINEFMNRDLLDVFAYGRYSNEVMTFVKNHGIDMDFQPEDEDVFIKLTSDFIAFSYYRSDTISAAQVPEGTIPNHYLDEGIKKNPYLETSEFGWQIDPLGFRDILTKVYNEYGIPMFPIENGIGVREKFDGGEIQDDYRIKYHRDHIQAMEDAIFEDGVDVIGYLGWGLIDIPSSSGNMDKRYGTVYVNRTNHDLLDMARVPKKSYWWLKHVIETNGADLGDI
>NZ_CP019323.1|WP_076614357.1|930349_931705_+|PTS-sugar-transporter-subunit-IIC
MSKESTSEKLEHSSFLDKFTQISVTVGNWVYLRSLRDAFAVILPVFIIAGLGTLLNNTVFMWIFKGDTLTKVQVFGNAISNGTLNVASVLVAPMIGYALAKNKGFNNPIAAAAMSLASLFIMMPGTVSLTDAAGKAHNVTGGLSFLNTGTQGMFGGIIIGLVATAMFIKLAGVKKLQINLGENVPPAVSSSFSVLLPALILMSFFALIAALLAGFFNTDLINLIKNWVQEPLRGFNTSILGFCVIYFVANFLFTLGIHQTVISGSLMDPLVLINMNQNMLAYAHHAHIPNIITTSFVSNYVLVGGSGSTISLIIAILLFSKVKSSKDVAKLSLAPGIFNINEPMIFGYPIVFNLPMMIPFVLFPIIGALMGYYATLLGIVSKTVVLVPWTTPPLIGPYLSTAGDWRAVVLQVVILAIGVVLYLPFMKISERVAAKQAEQLHAEQDAGTVNA
>NZ_CP019323.1|WP_157886437.1|931728_931902_+|hypothetical-protein
MKFERIWFSYIAIALLILLGLFDLVNFGLSLTTISTFVVAILFIVTLHNKQSVKKRD

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP019323_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019323_9

963589-963686

Orphan

Consensus_repeat	Method
AAGAAATTGTGTTCTGTTACGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP019323_9

>merge|NZ_CP019323|9|963589-963686|CRISPRCasFinder
AAGAAATTGTGTTCTGTTACGCGTTTGCGAAGCAAACAAGAAGCAAGACTGAACTTGAACTAAAAATTTCAATAAAAGAAATTGTGTTCTGTTACGCG

>NZ_CP019323|9|9|963589-963686|CRISPRCasFinder
AAGAAATTGTGTTCTGTTACGCG	TTTGCGAAGCAAACAAGAAGCAAGACTGAACTTGAACTAAAAATTTCAATAA
AAGAAATTGTGTTCTGTTACGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019323.1\|WP_076614378.1\|956597_957068_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP019323.1\|WP_076618679.1\|963991_965221_+\|carboxylate--amine-ligase	unknown	unknown	gnl\|CDD\|226433
NZ_CP019323.1\|WP_076614380.1\|957715_958204_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076614382.1\|959017_959683_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076614379.1\|957130_957676_+\|DNA-3-methyladenine-glycosylase-I	unknown	unknown	gnl\|CDD\|377025
NZ_CP019323.1\|WP_076614387.1\|969033_971616_+\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|223650
NZ_CP019323.1\|WP_076614386.1\|965237_965702_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|238182
NZ_CP019323.1\|WP_076618683.1\|966156_968064_+\|peptidase-M13	unknown	unknown	gnl\|CDD\|341056
NZ_CP019323.1\|WP_076614390.1\|973921_975967_-\|Ig-like-domain-containing-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076614377.1\|955342_956467_+\|glycerate-kinase	unknown	unknown	gnl\|CDD\|376844
NZ_CP019323.1\|WP_083685918.1\|972344_972590_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_120270354.1\|960405_961608_+\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|277347
NZ_CP019323.1\|WP_076614381.1\|958194_959028_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213192
NZ_CP019323.1\|WP_076618686.1\|968322_969024_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_CP019323.1\|WP_076614383.1\|959721_960243_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP019323.1\|WP_120270358.1\|971664_972102_+\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133384
NZ_CP019323.1\|WP_076614389.1\|973173_973917_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|226674
NZ_CP019323.1\|WP_076614388.1\|972733_973147_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380361
NZ_CP019323.1\|WP_076614376.1\|954479_955280_-\|tyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|379135
NZ_CP019323.1\|WP_076614385.1\|961620_963498_+\|asparagine-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|273676

Protein	Function_ID	Function_description	E-value
NZ_CP019323.1\|WP_076614378.1\|956597_957068_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	1.47675e-31
NZ_CP019323.1\|WP_076618679.1\|963991_965221_+\|carboxylate--amine-ligase	gnl\|CDD\|226433	COG3919, COG3919, Predicted ATP-grasp enzyme [General function prediction only].	2.38159e-97
NZ_CP019323.1\|WP_076618686.1\|968322_969024_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	2.3333e-105
NZ_CP019323.1\|WP_076614379.1\|957130_957676_+\|DNA-3-methyladenine-glycosylase-I	gnl\|CDD\|377025	pfam03352, Adenine_glyco, Methyladenine glycosylase. The DNA-3-methyladenine glycosylase I is constitutively expressed and is specific for the alkylated 3-methyladenine DNA.	6.49269e-106
NZ_CP019323.1\|WP_076614387.1\|969033_971616_+\|FtsX-like-permease-family-protein	gnl\|CDD\|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	8.07569e-12
NZ_CP019323.1\|WP_076614386.1\|965237_965702_+\|universal-stress-protein	gnl\|CDD\|238182	cd00293, USP_Like, Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae Usp reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, athough Usp lacks ATP-binding activity.	3.44736e-17
NZ_CP019323.1\|WP_076618683.1\|966156_968064_+\|peptidase-M13	gnl\|CDD\|341056	cd08662, M13, Peptidase family M13 includes neprilysin and endothelin-converting enzyme I. The M13 family of metallopeptidases includes neprilysin (neutral endopeptidase, NEP, enkephalinase, CD10, CALLA, EC 3.4.24.11), endothelin-converting enzyme I (ECE-1, EC 3.4.24.71), erythrocyte surface antigen KELL (ECE-3), phosphate-regulating gene on the X chromosome (PHEX), soluble secreted endopeptidase (SEP), and damage-induced neuronal endopeptidase (DINE)/X-converting enzyme (XCE). Proteins in this family fulfill a broad range of physiological roles due to the greater variation in the active site's S2' subsite allowing substrate specificity. NEP is expressed in a variety of tissues including kidney and brain, and is involved in many physiological and pathological processes, including blood pressure and inflammatory response. It degrades a wide array of substrates such as substance P, enkephalins, cholecystokinin, neurotensin and somatostatin. It is an important enzyme in the regulation of amyloid-beta (Abeta) protein that forms amyloid plaques that are associated with Alzeimers disease (AD). ECE-1 catalyzes the final rate-limiting step in the biosynthesis of endothelins via post-translational conversion of the biologically inactive big endothelins. Like NEP, it also hydrolyzes bradykinin, substance P, neurotensin, and Abeta. Endothelin-1 overproduction has been implicated in various diseases including stroke, asthma, hypertension, and cardiac and renal failure. Kell is a homolog of NEP and constitutes a major antigen on human erythrocytes; it preferentially cleaves big endothelin-3 to produce bioactive endothelin-3, but is also known to cleave substance P and neurokinin A. PHEX forms a complex interaction with fibroblast growth factor 23 (FGF23) and matrix extracellular phosphoglycoprotein, causing bone mineralization. A loss-of-function mutation in PHEX disrupts this interaction leading to hypophosphatemic rickets; X-linked hypophosphatemic (XLH) rickets is the most common form of metabolic rickets. ECEL1 is a brain metalloprotease which plays a critical role in the nervous regulation of the respiratory system, while DINE is abundantly expressed in the hypothalamus and its expression responds to nerve injury. A majority of these M13 proteases are prime therapeutic targets for selective inhibition.	0
NZ_CP019323.1\|WP_076614377.1\|955342_956467_+\|glycerate-kinase	gnl\|CDD\|376844	pfam02595, Gly_kinase, Glycerate kinase family. This is family of Glycerate kinases.	1.99053e-45
NZ_CP019323.1\|WP_120270354.1\|960405_961608_+\|metallophosphoesterase	gnl\|CDD\|277347	cd07402, MPP_GpdQ, Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain. GpdQ (glycerophosphodiesterase Q, also known as Rv0805 in Mycobacterium tuberculosis) is a binuclear metallophosphoesterase from Enterobacter aerogenes that catalyzes the hydrolysis of mono-, di-, and triester substrates, including some organophosphate pesticides and products of the degradation of nerve agents. The GpdQ homolog, Rv0805, has 2',3'-cyclic nucleotide phosphodiesterase activity. GpdQ and Rv0805 belong to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	1.62913e-05
NZ_CP019323.1\|WP_076614381.1\|958194_959028_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	1.8897e-30
NZ_CP019323.1\|WP_076614383.1\|959721_960243_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	7.51401e-07
NZ_CP019323.1\|WP_120270358.1\|971664_972102_+\|MerR-family-transcriptional-regulator	gnl\|CDD\|133384	cd01109, HTH_YyaN, Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB. Putative helix-turn-helix (HTH) MerR-like transcription regulators of Bacillus subtilis, YyaN and YraB, and related proteins; N-terminal domain. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	5.00261e-45
NZ_CP019323.1\|WP_076614389.1\|973173_973917_+\|SDR-family-oxidoreductase	gnl\|CDD\|226674	COG4221, COG4221, Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only].	1.14251e-101
NZ_CP019323.1\|WP_076614388.1\|972733_973147_+\|cupin-domain-containing-protein	gnl\|CDD\|380361	cd02233, cupin_HNL-like, Granulicella tundricola hydroxynitrile lyase (GtHNL) and related proteins, cupin domain. This family includes archaeal, eukaryotic, and bacterial proteins homologous to hydroxynitrile lyase from Granulicella tundricola (GtHNL), a novel class of HNLs that does not show any sequence or structural similarity to any other HNL and does not contain conserved motifs typical of HNLs. HNLs comprise a diverse group of enzymes that vary in terms of their substrate specificity, enantioselectivity and the need for a co-factor. In plants, they catalyze the reversible cleavage of cyanohydrins, yielding HCN and aldehydes or ketones. Also included in this family is TM1010 from Thermotoga maritima, a protein of unknown function. Some but not all members of this family have N- or C-terminal carboxymuconolactone decarboxylase domains in addition to the cupin domain. Members of this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	3.5169e-50
NZ_CP019323.1\|WP_076614376.1\|954479_955280_-\|tyrosine-protein-phosphatase	gnl\|CDD\|379135	pfam13350, Y_phosphatase3, Tyrosine phosphatase family. This family is closely related to the pfam00102 and pfam00782 families.	2.17163e-79
NZ_CP019323.1\|WP_076614385.1\|961620_963498_+\|asparagine-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|273676	TIGR01536, Asparagine_synthetase_1, asparagine synthase (glutamine-hydrolyzing). This model describes the glutamine-hydrolysing asparagine synthase. A poorly conserved C-terminal extension was removed from the model. Bacterial members of the family tend to have a long, poorly conserved insert lacking from archaeal and eukaryotic sequences. Multiple isozymes have been demonstrated, such as in Bacillus subtilis. Long-branch members of the phylogenetic tree (which typically were also second or third candidate members from their genomes) were removed from the seed alignment and score below trusted cutoff. [Amino acid biosynthesis, Aspartate family].	1.99903e-151

>NZ_CP019323.1|WP_076614385.1|961620_963498_+|asparagine-synthase-(glutamine-hydrolyzing)
MCGIVGFVDKNIADKAPVIESMMDTIKHRGPNSSGELIDGSVALGFRRLSIIDIKSGMQPIYNEDRSKAIIFNGEIYNYQDVRKDLLKAGHIFATDTDTEVLLHGFEEWGIVELLKRIRGMFAFVIYDLETGDITGARDFFGIKPLYYYNRQGTFIFGSEIKSFLKHPNFKKELNKAALKPYLTFQYSALNETFFKNVFRIPEGHYFTFKKGKLSIKKYWDMQFKENNLSFEDTVKRIDESLRDSVKEHAISDVPVGSLLSSGVDSSYVTAILKPQHTYSIDFDTSTYEEGSSAKVLADKLGLENTRGVVTKDEAIKAMPLIQYYMDEPDSNPSCVPLYFLTKLASKDVTVILSGEGADELFAGYANYGYHSHSKAIRIFAEDLKKLPKSARYSLAHGLKKMPNFPGRLHLYESTAKAEEFFIGQAKIFTEQEAADLVKPDFEKSRSVKDIVMKSYSKVTEYSDEVKKMQYLDLHQFMSNDILLKADRMSMANSMELRVPFLDKEVAKVAEGIPTKYLLNSKDSKYALRVAAERALPKEWAKREKLGFPVPIRDWIRTEDVYHKFYKLFSEDYVNEFFDQDKILSMLDGFYKGQNDDRRKIWTIYTFLIWYKVFFINDGQKPTEN
>NZ_CP019323.1|WP_120270354.1|960405_961608_+|metallophosphoesterase
MIVLRYWENRKLNIKNFVKKVLRPKPSALISAQTDSLMRRLKPRRFVTDYITDVYNNNVRPNVSDNTVTLSVLTDTHAKAVASASYYGINGIRHIIEANSAVDDLDIDLNVHLGDLIDGSDKPEISRGLLRFAVENYQNNEKPFYIAEGNHDENDKYDEHKFVSSASFNRDDYDNLVTKFDFQQSKILRLNPVSKVSWFDKGDVRIIFLNTSDIPYILNNGSKKYDVKKVRGIREQQISDLITILEDTVDKHVVVFGHANLISPSGRSALNFNGDLIQQLFVSFNNKDRGQIKNELTGDFGVNLRYDFSSTGISKVSNYICGHMHYEKYYNVSGINHIILNCSALMGKKHGLTTDYNKKWDRKYNEISELAGYFVNIDPDKLRLQIFGYGAATRYVSFEI
>NZ_CP019323.1|WP_076614383.1|959721_960243_+|GNAT-family-N-acetyltransferase
MSSIYLRQAKADDLKRVIEIINGEKSALLVRGVNQWQQGYPDEEILKQDIEEGINYVLILDGEIVGTAALQQGYDKSYQSISGSWSDESEVTYSIIHRIAVESGHQGEKLTTALIQQLLTISYYLGYHDIRIDTHPDNRVMQHVITDNRFIERGNITLDIDQGIRKAYQIILK
>NZ_CP019323.1|WP_076614382.1|959017_959683_+|hypothetical-protein
MKVKVLLINFINLILRNFLYPTLLMIFLSFELAINSLLELNMNQKFGLLVIGVFFVSLLTSMNFLKNDAAVNRYLFQKINNYWLYFLMQVLTLTIVAIFSAIVMSIFSFTFSINSIVAILPLATTGLVGVGIAFICKPQWNNHPYIAQIGIVVFVYIALAGTGDNILNYIQWFIPPVSKVITIFQEQSSIRALIPVSIQQLVYSCVLIILSGTFYEKKMSN
>NZ_CP019323.1|WP_076614381.1|958194_959028_+|ATP-binding-cassette-domain-containing-protein
MAIVELITVKDLSLQNEGYFAFKHVTFSLTQNEILSIVGDSGSGKSQLLETLAKMKTADSGKIEYTPGVRIGYLPQFDPQIITKSVRNYLEEIRRFTGKLAVSQKQLKELIAYMGMSPYLDRQIRQLSYGLKQRLDFLAAVAGHPNVLLLDEPFSFQNSKYTSNMLDIIGDLKQNGSGIIIASTYQDSSITNYFDKFYIMKNKSLEEVKNKAEEIKCMLIFTVKSDSMALTTDISKYLASNISSLVELRIPLGMKDSVIKEMIDLNYQFEGARILEG
>NZ_CP019323.1|WP_076614380.1|957715_958204_+|hypothetical-protein
MNSETISKLAEWLDKNDVDIEKKTEKLDASKVYDIIDSLEVLRKPIKDYFDMTEDDYYQNESDHRLTLQNPTRKLSELHDRIQVNHVDGSLSDHEINFTYNHEDPYVKGEYNIKTDLNLVNYSFVVIGAVYNNTIVADIRNSISKDAILSIGLAARAIEEWQ
>NZ_CP019323.1|WP_076614379.1|957130_957676_+|DNA-3-methyladenine-glycosylase-I
MRCPWADSSKEMQEYHDTEWCKVSHDERYFFEMLTLELSQAGLSWETIIKRRSGYRTLFDGFDIDAVAKFDDAKKEELLKDPRIIRNKLKVNATINNARQIQVMHENNQRFSDYIWSFVDNKQIVNHYEDMSEMPAQTKLSQDISKNLKKRGFRFVGPTIIYSFLQSVGVINDHLDSCDFK
>NZ_CP019323.1|WP_076614378.1|956597_957068_+|universal-stress-protein
MEQDYKRILVPVDGSKEAEMAFRKAVTVAQMNGGHLDVLTVLDTKQFIGLHGGMLNGDVIYQLSEDAQKYLNELKEEAVKDGYPEQEIDIHVRFGEPKTVISQEFVEEYKNDLIMIGSTGMNAVTRLLVGSVSEYVTRNARTDVIIVRTDTDNSKI
>NZ_CP019323.1|WP_076614377.1|955342_956467_+|glycerate-kinase
MIFIIAPGKYPDNVSSRKIGQAIYSGISRAIPNADIVTMPVTDSRDGMPALVKHTIGGEWFELPFFDAFWQNKLGRYLITKIDGQDTVIMDSEQIVGLELAIGKTRDQLFHATSHGLGEFILDAISSGHKNIVICLGRTAVADGGLGALQVLGAKIYDEDGTIIPEGENPLINAYSVDLDGVKKLLPSRTRITILLNYSNNYEIRYKINYLNEAQENFLEDNLVYVTEKANEKYNLDVHPMPNSEAIKTLAGAFAMIDAHIFRSSFEWIANVTGMDSTIRSADVLVTATDDISAESMHDEMLYHLSKIAGNSKIPTFVLCNNFIDDFEDYEQLFTGIFSTQMSKYYLKEYDEQTLFDNYEAVANQLARTMMSFH
>NZ_CP019323.1|WP_076614376.1|954479_955280_-|tyrosine-protein-phosphatase
MDNATKKTHRILNLENGRNFRELGGYKTLDGKTIKYHKALRSAGLGDLSDKDVNFLGNYGLKTDIDFRSIDEAAKKPDKMPKGTKYVSLPVFKEDETEASKIQGTSIPDLDYVPIDGYNHMLEAYLDMVNGPQAKLAYQNFFSELLANSNNDEVLLFHCSAGKDRTGMGAFFLMSALNVPMTTIKDDYLLTNKASKSFIDHLLSQVVEHEPTLVDTIKALMTVNINYLETAQKAIEETSGSIDNYIREELKVSDHDISDLKKIYLM
>NZ_CP019323.1|WP_076618679.1|963991_965221_+|carboxylate--amine-ligase
MNVYGMARAFHELYGGVVDAYAGAQLAPTRYTEIINLTIYPGFAEDPVFIKKMREIAKKYENHDEPIILIGCGDGYAELISQHMEELSKTFICPYVGYDLLKSLNNKESFYKVADEHNLPHPLTKIITKAAYEDSDKSGLEVPFDFPVALKPANSVEWLDINFEGRKKAFTIHSNEEYMDIVSKIYDNGYNSDLILQDFIPGDDSNMRVLNAYVDKENHVKMMCLGHPILEDPTPQSIGNYVAIVPEFNQDVYDLVQKFLEDIEFTGFANFDMKYDARDKTFKFFEINLRQGRSSFFVTLNGYNLAKYVVEDYIEDSLDKQPTVYANKNKAQHKLWLGIPVKVFRKYAADNEASEYAEELIKQDRTGTTVFYDKDKSFKRWLLMTYMFHNYVKRFDKYFQANKGRDFKK
>NZ_CP019323.1|WP_076614386.1|965237_965702_+|universal-stress-protein
MDELKEYKVSKIEYSKILICVDSDDFTSSKNAFNYACSLARHYGAELGIASVLETGDLNIFQSLDPEVLKDRRNEIKELLESYGQKAKTYGVENVHLMVTEGNPGSVIVEKVIPSFKPDLVIVGVEEKNRHRNTIGSQASKIVNNSRVSVSVIR
>NZ_CP019323.1|WP_076618683.1|966156_968064_+|peptidase-M13
MVNAKPADYKENLYLAVNGAWQEHAEIPADKPRTGGFMDLDEGVEKSLMKEFHEFANDEGKINDDLMLQAVKLYRLTNNVEHLNKFHHQPILKDIQKINDITSLQEFSDNLAELSKNGFPLPIDISIDADMKDTSKNVVYIGGASLILPDKTYYAKGNKSGEQLLAKFSEVATKLLSMIGYNLDDAKAIVQKALEFDKLLVPIVKGSEEWADYTKMYNPMPFDEYVTKSDSVDLSSQVTEQINDTPKMVIITEPRYLDNLNKIINEDTFENIKAWMMVNFLTGNASSLDEEFRQVIGEYNLALSGAKELQNRTKFAYHRAAGIFSQVVGVYYGKKYFGEDAKKDVRNMIKTMISIYEQRISDNTWLSEDTKKKAIVKLDKIEVKVGYPDKIDDIYNKISINENDSLYDNLREIRKIFIQDSLDQYHKSVDRTKWLMPGHMVNACYDPSRNDITFPAAILQAPFYSLDQTSSENFGGIGAVIAHEISHAFDNNGAQFDEFGNMNNWWTKEDYSKFTELTQSMIDEFNEVPFAGGKVNGKLVVSENVADVGGLRCALEAAKTEDDYDVKKFFINWARVWRLKATQEFNELLLSTDVHAPGPLRANVQAQNMDEFYPAFDVTKDDGMWLDEDKRVNIW
>NZ_CP019323.1|WP_076618686.1|968322_969024_+|ABC-transporter-ATP-binding-protein
MAYIEVKNEYKRYQMGETQIIANDDLTFDIKRGELTVILGPSGAGKSTVLNILGGMDTPSDGQVIIDGTDIAQFSERQLTEYRRNDVGFVFQFYNLIPNLTTKENVELASAIVDDALDATEVLNQVGLSGRIDNFPSQLSGGEQQRVAIARALAKNPKLLLCDEPTGALDYETGKQVLTLLQDASHKDNKTVVIITHNSALAAMADRIIRINDAKVRSVEDNSTPTPVQDIEW
>NZ_CP019323.1|WP_076614387.1|969033_971616_+|FtsX-like-permease-family-protein
MKPLTRNMYRDIGKSKGRFIAIILIIMLGVLTFVGVKAAGPSLNDSLDKTVTAKKLSDIQVISTTGFTKKDIDLAQKTKGAKAETVKYKQVTGGKSHVAISLYGYKKANNQNQLIVRSGRLPKNNSEIILDQVAKTKYNYKLGDKFTFDKSADLKSRTYKVVGFASSPQYIDNESRGSSNVGDGTVRMFAYIYDKQMNLPFATELNVRFKSLQAKNTFTNSYKDAVDDKVDSLKARFKNRASTRTKSLLGDNLSVINSQQEQLDQAKSQLQQAKSLGSDVTSQEQTLNAQQAKLTAAKKKLQEQTKTTYTWQTREDLPGFSDYGESSDRIAAIANVFPVFFFLIAALITFTTITRMIEEARGQIGTFKALGYTKWEIAKNYFYYALAAGLIGTIMGAVIGNESLPRIVLALYKQYIPLTWDVKFQWVYALLALAFSLIATVAAAMIVVRQELSEGPADLMRPKAPKSAKKILLERIKPLWNHLSFNRKVSYRNLFRFKSRMFMTIIGIAGGTALILTGFGIQNSIGASGTRQYNEIFNYQAVVRLTKNNQTKKALKVLNDSKQYRSSTAISATTGKVFANGKNVDDVNIYTPENKDFSKYIHLENTKKNKTIKLKDNEVVLTKKMANTLNVKAGDSIKINTTNNKGGKIKVSAVTQNFVGHFMYLNKETYNQLFKTQPKVNTLLVNLSTQTNKQRNSLANKLLNHGGVVGTSYTYDQQSTIAKMTSSLKPIVLIFILLSGVLSFVVLYNLTNINVSERIRELSTIKVLGFYNNEVTMYIVRENIILTIMGIIVGYGVGNLLTAYILNQASTPLVIFPLTISVIGYIVATVLMILFTMIVMLITHQKLKGIDMIGALKSNE
>NZ_CP019323.1|WP_120270358.1|971664_972102_+|MerR-family-transcriptional-regulator
METKISEKQYRIGDFAQVTGLSSPTLRYYEKEGLIKPHRTDNGLRYYTDQDAGWIKFLLHLKSTGMTIEQLKKYVQWRAEGDSTIDKRVALLQEVHDNFEKEFAELQHSWTILNDKLDWYKGKVNGHIEDSESFARYLKRLNHQE
>NZ_CP019323.1|WP_083685918.1|972344_972590_+|hypothetical-protein
MIIKAHKQGNSMMITLPSFLKVEEGTSFEPRMLENGTIELVPTTKNPSSMKELFKNWNGKYNPDPEMKDWDNINPSGNEIM
>NZ_CP019323.1|WP_076614388.1|972733_973147_+|cupin-domain-containing-protein
MAKFEELKDEGVFPVGDKNEAYAKYFIGQSYLQNLVSSDDNIDVSVGNVTFEPGCRNDWHIHHDGFQILLVTGGTGWYQEAGKPAQLLKQGDVVAIHEGVKHWHGATKDSWFSHVAITKGTSEWLEKVSDAEYAKLG
>NZ_CP019323.1|WP_076614389.1|973173_973917_+|SDR-family-oxidoreductase
MSVENKVVVITGASSGIGEATAKLLASNGAKVVLGARREEKLAKIVADIESAGGTAAYKVTDVRDPKEVSALVQLANDKYGKLDVIFNNAGIMPSSPISALHTDEWNDMIDINIKGVLNGVAAVMPEFTKQKHGHIITTSSVAGINSYPGAGVYGATKFAVRNLMEVIRMESAQEGTNIRTSTLYPAAINTELLNTITDKDARKGMDALYNQVGIAPISIARVVQFAIDQPEEVNVNEFTIYPTKQA
>NZ_CP019323.1|WP_076614390.1|973921_975967_-|Ig-like-domain-containing-protein
MRCKFKRIVAAILCAVTFFCLIKVTSTLSDGNFQLQYDVSAASAKTPTDPPIKIIGIWLTSGYDLQPDTDNYTTVNNPITLYTNAGRSIFSTLLSLTASPHYQWYSSTDGLIYSKVSSSNGGTDKNLTINPSTIGTKYYQLWTDWYTLVSWGLFDTTAYTNVINVHTLSDPINAKSMTVSSGSNYLYNNLTSSLSGLFTYPTADTTSMHTNTIPNNATGTVKWYSSDSSIASVDENTGVVSSNTDGKDGTVTIRGVYTNPDGTTLSDSTKIKVGGGLDDETTSVGDKATFTLQGSYSSAGNVSTSIEWHRVSADGKSDTVVSKGSSLSYTTAATTLSDDGTYYYAKVKVSQSDSTGKISTQTGQTNKAKLNVLTKGDPDISQKIELADTQTGADSDSVLNNVMTGDQLVLSDTLTNKSSTGTLANGKLVIPIRKGSTLQTVALDNTILMLKGTMINNSVNITQDYNSNKGYDEVILSSPTNSGSGSALNFDLNQKHTVEIFYKIAKVDTKETLTTAPTISGTNSDSENYSSNGPFTTINFATGGISLDPSDISFGSHLQQPGAKLFDRTKATNSPNNVLTVDDSRRGIDGKSQIQISSTPLYKKDTDNTNQVLDSDLRYYDPDGTYSSLADGSVVIESTASGSPLSSITWIPTAGLRLYLPNEPTSGSYTGTITWSAITSV

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP019323_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019323_10

1102760-1102977

Orphan

Consensus_repeat	Method
GTAGCGAATTTGCGAAGCAAAGAGAAAGA	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP019323_10

>merge|NZ_CP019323|10|1102760-1102977|CRISPRCasFinder
GTAACGCGTTTGCGAAGCAAACAAGAGGAAAAAAAGAGAAGCGCATAAAGTAGCGAATTTGCGAAGCAAAGAGAAAGAGTATAATTTCGTAGCGAATTTGCAGAGCAAAGAGAAAGAACCAAAAAAGGAATACAGTTCGTAGCGAATTTGCAAAGCAAAGAGAAAGAACCAAAAAAGGAAATACAGTACGTAGCGAATTTGCGAAGCAAAGAGAAAGA

>NZ_CP019323|10|10|1102760-1102977|CRISPRCasFinder
GTAACGCGTTTGCGAAGCAAACAAGAGGA	AAAAAAGAGAAGCGCATAAA
GTAGCGAATTTGCGAAGCAAAGAGAAAGA	GTATAATTTCGTAGCGAATTTGCAGAGCAAAGAGAAAGAACCAAAAAAGGAATACAGTTC
GTAGCGAATTTGCAAAGCAAAGAGAAAGA	ACCAAAAAAGGAAATACAGTAC
GTAGCGAATTTGCGAAGCAAAGAGAAAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019323.1\|WP_076614500.1\|1097610_1098954_-\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|379084
NZ_CP019323.1\|WP_076614514.1\|1111024_1113361_-\|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl\|CDD\|319795
NZ_CP019323.1\|WP_076614505.1\|1101674_1102655_+\|ribose-phosphate-pyrophosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_CP019323.1\|WP_076614507.1\|1104900_1105695_+\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NZ_CP019323.1\|WP_076614504.1\|1101273_1101654_+\|YueI-family-protein	unknown	unknown	gnl\|CDD\|377952
NZ_CP019323.1\|WP_076614510.1\|1108179_1108617_+\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	unknown	unknown	gnl\|CDD\|273918
NZ_CP019323.1\|WP_125673055.1\|1092011_1093931_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076614511.1\|1108630_1110073_+\|Fe-S-cluster-assembly-protein-SufB	unknown	unknown	gnl\|CDD\|131035
NZ_CP019323.1\|WP_076614503.1\|1100950_1101190_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076614506.1\|1103055_1104507_+\|glycoside-hydrolase-family-1-protein	unknown	unknown	gnl\|CDD\|225343
NZ_CP019323.1\|WP_076614498.1\|1094289_1096230_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076614499.1\|1096971_1097256_-\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	unknown	unknown	gnl\|CDD\|225619
NZ_CP019323.1\|WP_076614496.1\|1091144_1091891_+\|glycerophosphoryl-diester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176505
NZ_CP019323.1\|WP_076614508.1\|1105705_1106989_+\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NZ_CP019323.1\|WP_076614509.1\|1106975_1108193_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NZ_CP019323.1\|WP_076614515.1\|1113440_1114103_+\|HAD-hydrolase-like-protein	unknown	unknown	gnl\|CDD\|319798
NZ_CP019323.1\|WP_076614502.1\|1099923_1100697_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|366154
NZ_CP019323.1\|WP_076614512.1\|1110269_1110524_+\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	unknown	unknown	gnl\|CDD\|274102
NZ_CP019323.1\|WP_076614501.1\|1099102_1099855_-\|tyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|379135
NZ_CP019323.1\|WP_076614513.1\|1110516_1110801_+\|type-II-toxin-antitoxin-system-YafQ-family-toxin	unknown	unknown	gnl\|CDD\|379750

Protein	Function_ID	Function_description	E-value
NZ_CP019323.1\|WP_076614500.1\|1097610_1098954_-\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|379084	pfam13240, zinc_ribbon_2, zinc-ribbon domain. This family consists of a single zinc ribbon domain, ie half of a pair as in family DZR. pfam12773.	3.44476e-07
NZ_CP019323.1\|WP_076614514.1\|1111024_1113361_-\|HAD-IC-family-P-type-ATPase	gnl\|CDD\|319795	cd02609, P-type_ATPase, uncharacterized subfamily of P-type ATPase transporter, similar to uncharacterized Streptococcus pneumoniae exported protein 7, Exp7. This subfamily contains P-type ATPase transporters of unknown function, similar to Streptococcus pneumoniae Exp7. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids. They are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle. A general characteristic of P-type ATPases is a bundle of transmembrane helices which make up the transport path, and three domains on the cytoplasmic side of the membrane. Members include pumps that transport various light metal ions, such as H(+), Na(+), K(+), Ca(2+), and Mg(2+), pumps that transport indispensable trace elements, such as Zn(2+) and Cu(2+), pumps that remove toxic heavy metal ions, such as Cd(2+), and pumps such as aminophospholipid translocases which transport phosphatidylserine and phosphatidylethanolamine.	0
NZ_CP019323.1\|WP_076614505.1\|1101674_1102655_+\|ribose-phosphate-pyrophosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	2.75799e-149
NZ_CP019323.1\|WP_076614507.1\|1104900_1105695_+\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	3.12946e-139
NZ_CP019323.1\|WP_076614504.1\|1101273_1101654_+\|YueI-family-protein	gnl\|CDD\|377952	pfam07997, DUF1694, Protein of unknown function (DUF1694). This family contains many hypothetical proteins.	1.34197e-33
NZ_CP019323.1\|WP_076614510.1\|1108179_1108617_+\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	gnl\|CDD\|273918	TIGR01994, Iron-sulfur_cluster_assembly_scaffold_protein_IscU, SUF system FeS assembly protein, NifU family. Three iron-sulfur cluster assembly systems are known so far. ISC is broadly distributed while NIF tends to be associated with nitrogenase in nitrogen-fixing bacteria. The most recently described is SUF, believed to be important to maintain the function during aerobic stress of enzymes with labile Fe-S clusters. It is fairly widely distributed. This family represents one of two different proteins proposed to act as a scaffold on which the Fe-S cluster is built and from which it is transferred. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	7.82482e-65
NZ_CP019323.1\|WP_076614515.1\|1113440_1114103_+\|HAD-hydrolase-like-protein	gnl\|CDD\|319798	cd04302, HAD_5NT, haloacid dehalogenase (HAD)-like 5'-nucleotidases similar to the Pseudomonas aeruginosa PA0065. 5'-nucleotidases dephosphorylate nucleoside 5'-monophosphates to nucleosides and inorganic phosphate. Purified Pseudomonas aeruginosa PA0065 displayed high activity toward 5'-UMP and 5'-IMP, significant activity against 5'-XMP and 5'-TMP, and low activity against 5'-CMP. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.73029e-72
NZ_CP019323.1\|WP_076614511.1\|1108630_1110073_+\|Fe-S-cluster-assembly-protein-SufB	gnl\|CDD\|131035	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB. This protein, SufB, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_CP019323.1\|WP_076614506.1\|1103055_1104507_+\|glycoside-hydrolase-family-1-protein	gnl\|CDD\|225343	COG2723, BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase [Carbohydrate transport and metabolism].	0
NZ_CP019323.1\|WP_076614499.1\|1096971_1097256_-\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	gnl\|CDD\|225619	COG3077, RelB, DNA-damage-inducible protein J [DNA replication, recombination, and repair].	1.43359e-09
NZ_CP019323.1\|WP_076614496.1\|1091144_1091891_+\|glycerophosphoryl-diester-phosphodiesterase	gnl\|CDD\|176505	cd08562, GDPD_EcUgpQ_like, Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46), UgpQ, and similar proteins. GP-GDE plays an essential role in the metabolic pathway of E. coli. It catalyzes the degradation of glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols, which are major sources of carbon and phosphate. E. coli possesses two major G3P uptake systems: Glp and Ugp, which contain genes coding for two distinct GP-GDEs. UgpQ gene from the E. coli ugp operon codes for a cytosolic phosphodiesterase GlpQ, which is the prototype of this family. Various glycerophosphodiesters, such as glycerophosphocholine (GPC), glycerophosphoethanolanmine (GPE), glycerophosphoglycerol (GPG), glycerophosphoinositol (GPI), and glycerophosphoserine (GPS), can only be hydrolyzed by UgpQ during transport at the inner side of the cytoplasmic membrane to alcohols and G3P, which is a source of phosphate. In contrast to Ca2+-dependent periplasmic phosphodiesterase GlpQ, cytosolic phosphodiesterase UgpQ requires divalent cations, such as Mg2+, Co2+, or Mn2+, for its enzyme activity.	5.24181e-87
NZ_CP019323.1\|WP_076614508.1\|1105705_1106989_+\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	5.47512e-117
NZ_CP019323.1\|WP_076614509.1\|1106975_1108193_+\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_CP019323.1\|WP_076614502.1\|1099923_1100697_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	4.68104e-33
NZ_CP019323.1\|WP_076614512.1\|1110269_1110524_+\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	gnl\|CDD\|274102	TIGR02384, Putative_antitoxin_RelB, addiction module antitoxin, RelB/DinJ family. Plasmids may be maintained stably in bacterial populations through the action of addiction modules, in which a toxin and antidote are encoded in a cassette on the plasmid. In any daughter cell that lacks the plasmid, the toxin persists and is lethal after the antidote protein is depleted. Toxin/antitoxin pairs are also found on main chromosomes, and likely represent selfish DNA. Sequences in the seed for this alignment all were found adjacent to toxin genes. The resulting model appears to describe a narrower set of proteins than pfam04221, although many in the scope of this model are not obviously paired with toxin proteins. Several toxin/antitoxin pairs may occur in a single species. [Cellular processes, Toxin production and resistance, Mobile and extrachromosomal element functions, Other].	1.12054e-17
NZ_CP019323.1\|WP_076614501.1\|1099102_1099855_-\|tyrosine-protein-phosphatase	gnl\|CDD\|379135	pfam13350, Y_phosphatase3, Tyrosine phosphatase family. This family is closely related to the pfam00102 and pfam00782 families.	1.6107e-72
NZ_CP019323.1\|WP_076614513.1\|1110516_1110801_+\|type-II-toxin-antitoxin-system-YafQ-family-toxin	gnl\|CDD\|379750	pfam15738, YafQ_toxin, Bacterial toxin of type II toxin-antitoxin system, YafQ. YafQ is a family of bacterial toxin ribonucleases of type II toxin-antitoxin systems. The E.coli gene is expressed from the dinB operon. The cognate antitoxin for the E. coli protein is DinJ, in family RelB_antitoxin, pfam02604.	1.03165e-32

>NZ_CP019323.1|WP_076614505.1|1101674_1102655_+|ribose-phosphate-pyrophosphokinase
MSSTSLDKIALLSLNGNKPLAKRISEYMGVPLLDASVSHFADGEINIQINESIRGKDVYIIHSVSDPVNDNFMELMIAVDALRRASTKQIICVLPYFAYTRSDRKSRAREPISAKLFSNMLEMGGVDRVIALDMHADQIQGFFDIPVDHLRAMPIFAKYFMDKMDDKKDDFVFVAPDHNSMKRARSLAEVFGSQIAIVDQRSTEEQSVVPGVIGDVEGKKCVIVDDLIDTGTRMINSAEALKEAGAVDVYAAATHPIFSKTAAKDLQKSALKEIVVTDSIVVPDECKFDKLKILSVTDLLGDSIRKTELDESTSSLFKVRDSYTLI
>NZ_CP019323.1|WP_076614504.1|1101273_1101654_+|YueI-family-protein
MTDVEDYIKKNVFGKPQLKPDEKNKFLGNFAERVGIALTVAQLKNPANMKTVEGVMKKYPQYHLYLNGKIDSYILDKYLQLSVKLKYKFTIVSQSAVRNKERVMTDNDMGLVIADESRPIDRPVLI
>NZ_CP019323.1|WP_076614503.1|1100950_1101190_-|hypothetical-protein
MDEMVFFNPGDAIANSKDFGEAVRGAQIYKAKDPYESSLIIAEDVSDKKSFVVYFAKDEKSKVKDSDKSVVPYHFKKKL
>NZ_CP019323.1|WP_076614502.1|1099923_1100697_+|glycosyltransferase-family-2-protein
MVKNKLSIIMTTFNAASYVMSMLDSLIAQTNKDFELVVVDDCSTDKTLDIIASYEKKYDWITVYEHTQNSGVSAARNTGLKHISGNLVNFIDGDDWLEPGYVDFFLTVFENTDTDLVTCGFFMDTENGKSKVKTEKRQNGFVDRDEAIKQITKISGTVMGYTWNKVYRRSIIENNEIHFQTDLDLMEDQVFNVEYATVAKKFYLDNLPLYHYVSRKDSITKKFFDIDNVRDVGVANLRVLKTIRSSKLDKDSKREME
>NZ_CP019323.1|WP_076614501.1|1099102_1099855_-|tyrosine-protein-phosphatase
MKRILNLDGAINLRELGGYKTTDGKQIKYNKLLRSGDISNLTPQALKYLKNYGLKYVVDFRGDNEQQMWSDRNTDFYKIYSDPVYPLKGNGDKLASSLNNTSSYLGLIYQSVLLDKNGQQAYQLLFNLLLENNKDNNSVLFHCAAGKDRTGMAAILILKALGVDDETITRDYLLTNLMYASPSVINGTLNDESGDQDINKMNMTKADLESITSVFDAIEHYYGSFENYLTQALKFDKNKLNQLRNIYLEK
>NZ_CP019323.1|WP_076614500.1|1097610_1098954_-|zinc-ribbon-domain-containing-protein
MFCPNCGQRVDPSQKFCDHCGYDLTSIKNKRNESDQNQAKKDDDTIKSLADIEAELNDSEPESKSVPEKEINNYQQAPAQKKEYNSLRQASEVENTKQNTVRTFESTKKVPDDTLDDRTVAYDKDAFRQASKKPYQYAKSAQEQHDPSLNETQDLGKKFKERFKTSEDPFKPTKSEMKKLQQKKKQQEESDTSDGLIHNMGKFAKNNIYLCIFAVIIVAILLVVKRNYGFIALALAVLLWFLASQVSHGGEVSANKKFKRDNHPQSGSDEYNENNDHQEQQYKEPKKHKTHDNRRGKNMRQKVIIGSSVIGFVASIGGPFINGVSLSSTIASAASYTANFGYQYSTIIVNLSSAIRLICFLSPIIAMIAACFRNRGSVKLVRLFTVLPTIIYAVVFAIFYSGAVNSALITGQTAVNGTQFGISFYILLVTSIVSLVMAYALHPRERL
>NZ_CP019323.1|WP_076614499.1|1096971_1097256_-|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin
MARIEARIDGTIKNKAKDVLANHGLTISDFMRMTLTTVANEGLPKYYSIPNRQLKDSIQEVVDDLSGKEKLPEAHNLKELDQLLSSDDTLRPSK
>NZ_CP019323.1|WP_076614498.1|1094289_1096230_+|hypothetical-protein
MRRKKGIVFVTLLFTLLTVVFFVNETRSVSADDTEIGYYKKPTGDVRKFLGIWLTSGYNLQPSTDNYVQVNNTVTLHTDSGRSVWDRAISLNGFSHYKWYQSTDGQKWSKVPDKENGDRKHMPVTPTTTGTVYYQQRVAWYYLFEVLTSPVVYSQVAAVHSLPDPVNATDVEVTTDDDYLYNSDNDVTDTTTYAHADITPANFTGTLSWSIDDTNLATIDEDTGLITANTLRKSGTVTVTATLTNPDGTITTGDTKVQIGGGLDDQTVKAGKTATFSLRGNIGELDEDDTSYSVKWYKEDPITHYRTQLDVDSKALSITTPETTLDDDGTLYLAIIQVKMGTTSMSYTTNDAFLYVTPEGGPDINIDDTLENETFNDNTNTDTMLYGVINGDKVTYHNTITNDSQTGTLSDGKYVLPLHSDTEVTKVTLDGTELSSDEYEVTENDTTKEINLIISDLNFKNNQSHSIDVETVVGGITKKETTQTIPYITGKDDDGDSYQKIGKVESISYSTDMIEQSINDIDYGEVVSYGQEALVYRSDDLNWPNNLIEIDDMRRYKNPVTVSVSQGADLENEKGQTLSGNLRYYDDDGKYTDLLSSSAVVKSTAENEQLESIGWYKNNGLVLYLNGASSAGVYTTQLNWEISDTI
>NZ_CP019323.1|WP_125673055.1|1092011_1093931_+|hypothetical-protein
MRRILFLLVIMLIFVITGGISIKNVTADSEDVKPLNKPSDPPHSFLGVWTSSGYTLQPDAQNYTTPGHKVVLNTKAVKSGWGFMDANYRWYKSTDGGVNWSEVSDYDAGMTKNLHITPKEVGTTYYQQKAVWTGSWFNSTQVAWSQVAAVHVVPQDIYAKKIQLSHDDDYLYNTKNEIAPNSTLVREQVDPDNYTEDLVWSVDNSELASIDTETGELFANLLGKSGVVTVSATIDNPDGTTISASTKVIIGGGLADQVTESGKSARFTLLGRIGKLDLNSKEESEYTIKWFRQPVGTSQSIEVDASSNKASFIDVTDPKMKNSGDLYWAVINVRENGKDHSYTTNKAKLTVEPTDKPNIELNNEVKNESFDVDNIDTVLNQVSHNDKVVYENDIINKSDGGSLVNGEFVLPIRPGTGIDSVIIDGVKLDPKDYRYVAEYDDKSSALIIDNINCLPEQTRHIKISTTVGSITQNETLITQPQIVSNEEDHSYSKVGNILTLNYVTNILNKSIRDISYGSINAYSKEKIISRTLDTNMPNNVVEIKDQRRVKSPLKVFVSQISNFTNEKGILLPGSLRLYDNDKYVDIIENKSLVEASRQNEPVKSIGWSEKNGLLLYMHGSPVLEGKYSATLNWTFEDSV
>NZ_CP019323.1|WP_076614496.1|1091144_1091891_+|glycerophosphoryl-diester-phosphodiesterase
MSKKILAHRGIPTIAPENTMAGFNAVIDYGIDWIETDLSITKDESVFVIHDDKLDRTTNENGSIETLDASLVKKADAGSWFAEKFRGERIPTLDQLIDFLNIHKLNANVELKGVVGDDANHLADSLVSQFASAVDRLDPDVQLIISSFNPIMLQKMHELRPSLDYAMLFDCYGMGEDWNLYMQASHAKYIHPDSRGLTEAKVKKMKEYGYQVNVWTVDDVNRAQELFSWGVDGIFTNIADRMKFLVKN
>NZ_CP019323.1|WP_076614506.1|1103055_1104507_+|glycoside-hydrolase-family-1-protein
MTTTFPKNFLWGGATAANQYEGAWNEGGKGPSDSDMLLSGTYDKPRVFTKELKDDGYYPSHLGSDFYHHYKEDIKLLAGMGYKTYRMSIAWSRVFPNGDDATPNQEGLDFYRSVFEECHKYGIEPLVTISHYEMPYHLTDKYNGWGNRLAIDFYVKYAKTLFTEYKDLVHYWLTFNEINIGMMFGGYMSLGMKVKDGSAPFNPKQTDEDIQNNLQGLHHQFVASALAVKVGHEINPDNKIGCMIAGNVNYPLTSNPDDILKAQQTNEMMNYYCGDVQVRGAYPHFAQRFWDEHNVKLNITAEDEAVLKEGVVDYYTFSYYSSNAVTTDESKGEAGGNFTMGVKNPYLKYSEWGWAMDPKGLRWYLNDVYGRYQIPIMVVENGLGARDVVESDGSINDDYRIEYLQGHIEQMKEAIKDGVDLVGYTPWGCIDLVSAGTGQMEKRYGFVYVNRDDNQVGDFSRTPKKSYYWYKKVIASNGADLDN
>NZ_CP019323.1|WP_076614507.1|1104900_1105695_+|Fe-S-cluster-assembly-ATPase-SufC
MSTLEVKDLHVSVTDEENGLGQEILKGVDLTMSTGEIHAIMGPNGTGKSTLSQAIMGNSKYKVTQGDILLDGESILEWPVDKRARAGLFLAMQYPAEIPGVTNIEFMRAAINARREKDDQIPVRKFIKKLDEKQEILDMTDAMSGRYLNEGFSGGEKKRNEILQLLMIEPSFAILDEIDSGLDIDALKVVSRGVNSMRGDKFGSLIITHYQRLLNYIVPDQVHIMMGGRIVQSGGPELAKKLEDEGYAGIRDDLNIDVKLTDEI
>NZ_CP019323.1|WP_076614508.1|1105705_1106989_+|Fe-S-cluster-assembly-protein-SufD
MRPSLKDKYMDDVIQFSQQNNEPDWFTKFRTDNLTSSSDLSLPTYEKINYRSWRLDRPSDFSTTSNISDYKHTQSKSYIVQSGSKTLDLKLQQSLVDAGVILTDIFTAIREYPELIQKYYMTKVVKPDENKLTAIHAAMMNGGIFLYIPTGVKVTDSIQATFIQDNNIKRDFNQHVLIIAEDNTELTYLETFSSKGDVEENKSNIVVEVIAGNDCHIHFSALDQMSKKTTSYLSRRGITGNNSRIDWAIGFMNDGNIIGDFGTDLIGEGSHTEAKVVAITTGDQVQGIDTKVTNYGRHTIGHILQHGVILESSTLTFNGVGHIVKGARGSDAQQESRVLMLSRKARGDANPILLIDENDVTAGHAASVGRVNEEQMYYLMSRGIDEPTAQRLVIRGFLSSVITEIPEEEVRERLTQMIERKLINGQQ
>NZ_CP019323.1|WP_076614509.1|1106975_1108193_+|cysteine-desulfurase
MDNNDFPILHQKVNDEDLVYLDNAATTQKPKQVIEAMEKFYYNDNANVHRGVHTLAERSTEQFEDARQKVQKFINAKSTKEIIFTKGTTDSLNMVAQSFGENIHEGDEIVISIMEHHSNLIPWQQLAIKKHATLKYIELTDDGQLDMSQAKSLINDRTKIVSVAHVSNVLGVINPVKELAKLAHKHGAVMVVDGAQSTPHMPIDVQDMDCDFFAFSGHKMLSETGIGVLYGKEKLLEKMTPVEYGGEMIEFVKKFSTTFNDLPWKFEAGTPNIAGAISLGFAIDYLNGIGMQNIFDYEQKIVSYVLPKLLAIDGIEVYGPKDPKLHTAVISFNLLGLHPHDLATGLDMEGVAVRAGHHCAQPLMTYLGLSATARASFYFYNSLEDADRLVGAIRATKEFFKHGTI
>NZ_CP019323.1|WP_076614510.1|1108179_1108617_+|SUF-system-NifU-family-Fe-S-cluster-assembly-protein
MALSRMDDLYRQVILDHSDNPHHHGELSNANKSIELKNPTCGDVLTLDLDIENDVIKDMAFGGYGCTISQASASMMTDAVIGKKTSEAEQMVQTFSNMIIGEDVDTDSLEDAAVLEGVSKFPARIKCATLAWKALHKAMNKKDSE
>NZ_CP019323.1|WP_076614511.1|1108630_1110073_+|Fe-S-cluster-assembly-protein-SufB
MPETENTKNNEDAVSSVEDLGLSDDYDFGFHDDVKPVFTTGRGLTEDVVRAISKEKKEPKWMLDFRLKCYETYKKMPMPDFGPDLSKLDLKNMRYYQKATDKKYRDWDDVPTELKNTFDRLGVPEAERQYLAGSSAQYESEVVYHNMRDEFAKFGIIFTDTDTALREYPELFRKWFGKLVHPNDNKFAALNGAVWSGGSFIYVPKGVKLDIPIQSYFRLNAENSGQFERTLIIVDEGASIQYVEGCTAPNYSTDSLHAAVVEVYAQKDAYVRYTTIQNWSNNVYSLETKRAQAMENSTMEWVDGNLGSKITMKYPSVYLDGEGARGTMLSIAVAGKGVDQDAGARMIHNAKNTSSSIVSKSISKDGGAVDYRGTVRFERNSDGSKAHVECDTIIMDEESSSDTVPYNEILNGNVSMEHEAKVSKVSEEQLYYLMSRGLSEAKATEMIIMGFVEPFTKELPMEYAVELNRLIGYEMEGTVG
>NZ_CP019323.1|WP_076614512.1|1110269_1110524_+|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin
MSDTRISLRIDPELKKDAQELYSDLGLDLTSAVTMFLKQSVREQALPFKPELEDSESVQARKEAFKKDLKKYKTVDDWWDNLNA
>NZ_CP019323.1|WP_076614513.1|1110516_1110801_+|type-II-toxin-antitoxin-system-YafQ-family-toxin
MLEIVQTPTFVKDFKKLKKKHYNMLLLKKVVTHIVKGENEILVSKYRDHALKGNWQGFREVHIEKDWLLVYLVNKGELRLALIRTGSHSQILGK
>NZ_CP019323.1|WP_076614514.1|1111024_1113361_-|HAD-IC-family-P-type-ATPase
MVKVKRPTEYTDLDTGLNQQQINQKISNGQTNVQIKKLSRPIPKILSDNLFTLFNFVNLVIAVLIFWTGSYRNLFFLGPVIANIVIGSYQEIRSKITVDKISLVNEQDFPTLRDKKIVNVAIEDLVEDDIVCLKRGNTIPADGIVRYTNGLQTNESSITGEADSIVKSVDSEVFSGSFVVAGQAKIQLTQVGLNSNVSQISSAVGKDKRSVSVLMRIINNIIKILTYTIIPIGLLLFFRSFLKNGDVSTSILRTSASVIGMIPEGLVVLTSIALATGAYNLSKKNILVRSLSAIETLARVDTLCLDKTGTITTGKLSIKDTLSYNNYSENQVQSIATKIVDVTKETNATALAINKLQIKGTDEEVSEVIPFSSESKYSGFVSKDGTRYIMGAPEFIIKNASEIITSKVDLAAQQGFRVIAVLKEKNELQTLIGLLMISDEVRPQATSTFSYLKNQGIDLKIISGDNPVTVANVAAQAGIDTNNSYIDMSEHLDEDYSNLVMNYKVFGRVRPSQKSALIKAMQDNGLTVGMTGDGVNDVLAMRQSDCSIAIAGESDAAEATADFVLLNRNFDSMIYMLNEGRRVINNVERVASLFLIKTIYSVVLSIMFIILGTGYPFEPSQLTPVNALTVGIPTFILALEPNYTPPAGRFMRNVMEIALPSAIVNILMISIIYFVGNHMNLSYHTTSTLCVFSIGIIGYCALISISNPLILRKKIMIAVSFILFMLAFMYTDKAFGIQSILIWRYSFLYLSIFLVSWPLFMFMREVLGRRVFSKINWK
>NZ_CP019323.1|WP_076614515.1|1113440_1114103_+|HAD-hydrolase-like-protein
MNNLFFDLDGTIINSEPGIMKSLKYMYNNTLGYVPHDDDTLRKFIGPTLGASFEKYDGIGLDDPKAREMFNTFKEYYAVDGWEQFKVYDGVKEMLMNLSGDGKQVFIATSKPETFAKKIIDQIGMKPYVRHVFGASDDEETRTLKEDVIAYGIKKTSINLNSDNLVMVGDRSSDIVGAHKNNLKAIGVTYGFGTREELDEASSEWIVNKPQDIVKLAMEK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP019323_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019323_11

1122821-1122948

Orphan

Consensus_repeat	Method
GAAGAAATTGTGTTTAGTAGCGCGTTTCAGCAAGTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP019323_11

>merge|NZ_CP019323|11|1122821-1122948|CRISPRCasFinder
GAAGAAATTGTGTTTAGTAGCGCGTTTCAGCAAGTTTGAGAAGAAAAAGAAGTAAAACACAAATCTTTTAGAATCTAAAAAAGTAAGATAAGAAGAAATTGTGTTTAGTAGCGCGTTTCAGCAAGTTT

>NZ_CP019323|11|11|1122821-1122948|CRISPRCasFinder
GAAGAAATTGTGTTTAGTAGCGCGTTTCAGCAAGTTT	GAGAAGAAAAAGAAGTAAAACACAAATCTTTTAGAATCTAAAAAAGTAAGATAA
GAAGAAATTGTGTTTAGTAGCGCGTTTCAGCAAGTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019323.1\|WP_076614528.1\|1123716_1124478_+\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|377026
NZ_CP019323.1\|WP_076614529.1\|1124711_1125206_-\|thiol-peroxidase	unknown	unknown	gnl\|CDD\|239312
NZ_CP019323.1\|WP_076614526.1\|1121872_1122724_+\|YitT-family-protein	unknown	unknown	gnl\|CDD\|224203
NZ_CP019323.1\|WP_076614533.1\|1127202_1127718_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
NZ_CP019323.1\|WP_043023465.1\|1128464_1129490_-\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP019323.1\|WP_076614522.1\|1119766_1120105_+\|CrcB-family-protein	unknown	unknown	gnl\|CDD\|376809
NZ_CP019323.1\|WP_076614534.1\|1127833_1128265_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|273478
NZ_CP019323.1\|WP_076614518.1\|1115535_1116918_-\|HlyC/CorC-family-transporter	unknown	unknown	gnl\|CDD\|224173
NZ_CP019323.1\|WP_076614521.1\|1119355_1119763_+\|CrcB-family-protein	unknown	unknown	gnl\|CDD\|376809
NZ_CP019323.1\|WP_076614535.1\|1129621_1130467_+\|WxL-domain-containing-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076614525.1\|1120876_1121740_-\|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224995
NZ_CP019323.1\|WP_076614517.1\|1114943_1115309_+\|iron-sulfur-cluster-biosynthesis-family-protein	unknown	unknown	gnl\|CDD\|366687
NZ_CP019323.1\|WP_076614532.1\|1126815_1127139_-\|Arc-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|367702
NZ_CP019323.1\|WP_076614524.1\|1120568_1120760_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076614530.1\|1125302_1125956_+\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|376405
NZ_CP019323.1\|WP_076614527.1\|1122956_1123598_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
NZ_CP019323.1\|WP_076614519.1\|1117113_1117662_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|133378
NZ_CP019323.1\|WP_076614523.1\|1120138_1120567_+\|DUF805-domain-containing-protein	unknown	unknown	gnl\|CDD\|377540
NZ_CP019323.1\|WP_076614531.1\|1125987_1126791_-\|SPFH/Band-7/PHB-domain-protein	unknown	unknown	gnl\|CDD\|223407
NZ_CP019323.1\|WP_076614520.1\|1118064_1118964_+\|decarboxylating-6-phosphogluconate-dehydrogenase	unknown	unknown	gnl\|CDD\|236582

Protein	Function_ID	Function_description	E-value
NZ_CP019323.1\|WP_076614528.1\|1123716_1124478_+\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|377026	pfam03358, FMN_red, NADPH-dependent FMN reductase.	4.0132e-15
NZ_CP019323.1\|WP_076614529.1\|1124711_1125206_-\|thiol-peroxidase	gnl\|CDD\|239312	cd03014, PRX_Atyp2cys, Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a bacterial periplasmic peroxidase which differs from other PRXs in that it shows substrate specificity toward alkyl hydroperoxides over hydrogen peroxide. As with all other PRXs, the peroxidatic cysteine (N-terminal) of Tpx is oxidized into a sulfenic acid intermediate upon reaction with peroxides. Tpx is able to resolve this intermediate by forming an intramolecular disulfide bond with a conserved C-terminal cysteine (the resolving cysteine), which can then be reduced by thioredoxin. This differs from the typical 2-cys PRX which resolves the oxidized cysteine by forming an intermolecular disulfide bond with the resolving cysteine from the other subunit of the homodimer. Atypical 2-cys PRX homodimers have a loop-based interface (A-type for alternate), in contrast with the B-type interface of typical 2-cys and 1-cys PRXs.	3.1134e-57
NZ_CP019323.1\|WP_076614526.1\|1121872_1122724_+\|YitT-family-protein	gnl\|CDD\|224203	COG1284, COG1284, Uncharacterized conserved protein [Function unknown].	2.81415e-59
NZ_CP019323.1\|WP_076614533.1\|1127202_1127718_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.38748e-12
NZ_CP019323.1\|WP_043023465.1\|1128464_1129490_-\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	3.87757e-70
NZ_CP019323.1\|WP_076614522.1\|1119766_1120105_+\|CrcB-family-protein	gnl\|CDD\|376809	pfam02537, CRCB, CrcB-like protein, Camphor Resistance (CrcB). CRCB is a family of bacterial integral membrane proteins with four TMs.. Over expression in E. coli also leads to camphor resistance.	2.38411e-15
NZ_CP019323.1\|WP_076614534.1\|1127833_1128265_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|273478	TIGR01167, Zinc_metalloprotease_ZmpB, LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other].	0.00725469
NZ_CP019323.1\|WP_076614518.1\|1115535_1116918_-\|HlyC/CorC-family-transporter	gnl\|CDD\|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	9.5365e-98
NZ_CP019323.1\|WP_076614521.1\|1119355_1119763_+\|CrcB-family-protein	gnl\|CDD\|376809	pfam02537, CRCB, CrcB-like protein, Camphor Resistance (CrcB). CRCB is a family of bacterial integral membrane proteins with four TMs.. Over expression in E. coli also leads to camphor resistance.	1.00492e-25
NZ_CP019323.1\|WP_076614525.1\|1120876_1121740_-\|NAD(P)-dependent-oxidoreductase	gnl\|CDD\|224995	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism].	1.83478e-112
NZ_CP019323.1\|WP_076614517.1\|1114943_1115309_+\|iron-sulfur-cluster-biosynthesis-family-protein	gnl\|CDD\|366687	pfam01521, Fe-S_biosyn, Iron-sulphur cluster biosynthesis. This family is involved in iron-sulphur cluster biosynthesis. Its members include proteins that are involved in nitrogen fixation such as the HesB and HesB-like proteins.	6.43814e-26
NZ_CP019323.1\|WP_076614532.1\|1126815_1127139_-\|Arc-family-DNA-binding-protein	gnl\|CDD\|367702	pfam03869, Arc, Arc-like DNA binding domain. Arc repressor act by he cooperative binding of two Arc repressor dimers to a 21-base-pair operator site. Each Arc dimer uses an antiparallel beta-sheet to recognize bases in the major groove.	0.000186583
NZ_CP019323.1\|WP_076614530.1\|1125302_1125956_+\|nitroreductase-family-protein	gnl\|CDD\|376405	pfam00881, Nitroreductase, Nitroreductase family. The nitroreductase family comprises a group of FMN- or FAD-dependent and NAD(P)H-dependent enzymes able to metabolize nitrosubstituted compounds.	6.16494e-28
NZ_CP019323.1\|WP_076614527.1\|1122956_1123598_-\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	3.24708e-51
NZ_CP019323.1\|WP_076614519.1\|1117113_1117662_+\|hypothetical-protein	gnl\|CDD\|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	0.00114132
NZ_CP019323.1\|WP_076614523.1\|1120138_1120567_+\|DUF805-domain-containing-protein	gnl\|CDD\|377540	pfam05656, DUF805, Protein of unknown function (DUF805). This family consists of several bacterial proteins of unknown function.	9.49495e-17
NZ_CP019323.1\|WP_076614531.1\|1125987_1126791_-\|SPFH/Band-7/PHB-domain-protein	gnl\|CDD\|223407	COG0330, HflC, Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones].	8.01529e-37
NZ_CP019323.1\|WP_076614520.1\|1118064_1118964_+\|decarboxylating-6-phosphogluconate-dehydrogenase	gnl\|CDD\|236582	PRK09599, PRK09599, NADP-dependent phosphogluconate dehydrogenase.	0

>NZ_CP019323.1|WP_076614526.1|1121872_1122724_+|YitT-family-protein
MEFIKNYYKSILAALFYGVTSAMGIQLFLQPSKIYTSGVMGASQLVVNLLEQFAHINTQVYIWYFIFNIPLVVVSWLKLGKKFTILSMIAIISASVFILFIPLHPITNDPMLASVFGGVMTGVGIGICFRNGFSTGGTDVIALIVQKSTGRTVGQVSFAVNAMIVIVAGIVFGWELALYTMVSIYISNVLVDKMYIQQQKVTVVVYSHYIDKISKELLQTINRGITLDYNLTGAYSGEPIGSMTMVLTKYELFFVKKSVLKIDPNAFINIQPTVEIKGNFNDN
>NZ_CP019323.1|WP_076614525.1|1120876_1121740_-|NAD(P)-dependent-oxidoreductase
MKTLGFIGTGVMGTGIINNLLKANYPVNIYTRTESKAEPLLKEGAKWFASPKIVAENSDIIFSMVGFPQDVKDVYFKDNGVFAGLTSGKIIVDMTTSTPTLAKEIGEKAEKLGVKTLDAPVSGGDVGARDGKLTIMVGGSKEAFDELVPLFEIIGQTNHYFGSYGSGQHAKMANQIMIAGTMTGMSEMFVYAKAAGLDMESVLKTVSGGSANNWSLDNYGPRVLKGDFKPGFYSKHFLKDLRIALDESEKMGLDLPATKQAKALYEKLVDEKDLGNDGTQALIKLWW
>NZ_CP019323.1|WP_076614524.1|1120568_1120760_+|hypothetical-protein
MFKKNKENQRFEVHSEEYIGQHGLSIITDKTTGVQYISDITGMGSGMTVLVDKDGKPLLNKET
>NZ_CP019323.1|WP_076614523.1|1120138_1120567_+|DUF805-domain-containing-protein
MEEKEIWNESDRPNLINSTKLYFQDMFVGAKRMSRADYWWGLFGITLVSAVVMGLFAWLVTVMPINDFYWSAVWSIALVMTCGYYLISIWTASIRRLHDRNMRAWWMFSYVLPVIGEVMMIVLMCLPQQNDNNNWAKFVEVD
>NZ_CP019323.1|WP_076614522.1|1119766_1120105_+|CrcB-family-protein
MSIFLVGFGAGIGAFFRNELTHLSRKITVDFPVITLLINIFGAFALGIFTAHINGSLLLFLGTGFCGGFTTYGTMNMELSQLWFQKKFVRCFLYFALTYIIGILGFIVGINL
>NZ_CP019323.1|WP_076614521.1|1119355_1119763_+|CrcB-family-protein
MTKSKSFIIIFIGAFIGSNLRYGESLLFKTSSGFPYGTLVANLSGALILPFLIHYLQDRFHLSANVILALSTGLLGSYTTFSTFTADAYRLYQMQNWIMLITYLTITITGGFICALIGNYLAAGSAFVDYSERGK
>NZ_CP019323.1|WP_076614520.1|1118064_1118964_+|decarboxylating-6-phosphogluconate-dehydrogenase
MKLAMIGLGKMGINLTENLIRNNNEVVAYDLSKDAKADAVKLGAKVADSLEEVINNLDTPRIVWVMLPAGNPTNSTVDTLSELLDQNDIVIDGGNSFYEDSLKHNEILKNKGIKFFDVGTSGGMDGANHDGNFMIGGDDEKLFSYIEPIFEGIAQTDGYLYTGKAGSGHYLKMVHNGIEYGMMQAIAEGFDVLTHSQFEYDNEAVAKVWSNGSVIRGWLMELAQSAFSKDSNLEEIKGVMHSSGEGKWTLEEALKLQVPTPVIAASLMMRYRSLEDDTMTGKVVSALRNEFGGHDVDKK
>NZ_CP019323.1|WP_076614519.1|1117113_1117662_+|hypothetical-protein
MSKAKSSKFLTPAKAAEDLGISVATLRKYSLIVEHTTKDSDYFERNSQNNRLYTSKNIEDFKQMVELGHRPKMTLDSAAKQIFPAADVEEETTEVKDEKVEELKTTISTLKAEAKKSEETIDDLKKKLADAIEEKDSLQSQFDRFREESKNKEDSVIKEKVNEQVQEEHDSSKGHWWNRFVK
>NZ_CP019323.1|WP_076614518.1|1115535_1116918_-|HlyC/CorC-family-transporter
MSSSTITTNLIIILITFIFAFFFVAAEFALIQTRPSQLEDAISKGEGNPKKLKRALMMVNNLNEYLSTTQVGTSIAGIILGWIGESTIEYLLIDFFGLIHLSNGSGGLHAIGSVVGVLLLTYLEVVLTEIVPKNVSIDMPLKMLMLTVTPMRIFHLSVYPFVWLLNSSASGIVKLMGLKPADSENEIFSQSEILRLSKSAVQGGDMDQNDVVFMQRAFELNDKVAKDIMVDRTSLYVVDITDNVKDVLKDYLQQGFSRFPVVADNDKDKVLGYVYAYDIVRQNQVDGEIGISRILRSVNTVPETMPIQDILSKMIKKQTPIVVVVDEYGGTSGIVTDKDIYEELFGTVKDEIDDVSDEYIVKNADNSYNVSGKTTLYDFERYFRADIPEFQESDIITIGGYIIEKYPNIGPDFELTMNNFKFKVVEFDHGFVNWFNVSVDKTAVTKQDNLASLTDVDDLK
>NZ_CP019323.1|WP_076614517.1|1114943_1115309_+|iron-sulfur-cluster-biosynthesis-family-protein
MKIELTNEAKNKLQAYVDNGKKIILDLDDGYGRFSGEGDCALITKFRIIAVDANENLSDYPITLDSEVGKIYYKKSAEDFLDDGLKLEVNPKTQLLVFKNTKEIIDSSVNIIDYDTVKANA
>NZ_CP019323.1|WP_076614527.1|1122956_1123598_-|SDR-family-oxidoreductase
MKVLIIGAHGKVGHLLTGELQSNNIEFVAGLRNQEQIDAYQANNMETQFIDLNASLDDIGNSIKESGADVIVFSAGAGGAGYDITMEIDLDGAIKTMIAAEAIGIKRYVMVSSIFSDDRSKWEASGIRPYMIAKHYADEHLRGSNLDYTIIHPGTLTNDDSIGKIEVLDPEKGGSIPRIDVAKSIATIITNPNTIKKEYSIISGDVDIDSAFK
>NZ_CP019323.1|WP_076614528.1|1123716_1124478_+|NAD(P)H-dependent-oxidoreductase
MKVLGILAAHQEHGINAKLLSAVLENVDSGVETETIFLEDYDITPHKYHEKNEVLDELSAKLAESDVWVFAAPTYWRELSGVLKNFFDCMRPKFVYFKENGDTIPGKFKDKHYLSISSCYVSTLENFVTGVTDDTFKTIDRVMSAAGVIKTGEIVLPGTFGMKEVPESKLKLCAKYGHKISQKKRKDDSTVKRYIQLFFMIAIMALITMGIQLPLKQVMPSNFWTDYVSFTIIFFVLLGSILHFVTFVKHRRR
>NZ_CP019323.1|WP_076614529.1|1124711_1125206_-|thiol-peroxidase
MDLDFKGKAVSTIGTPVSVGEKFPDFTVLDKDNKSITLDSLLDKPLLISVVPDIDTRICSLQTKHFNQEIDGHTEINFVTISKNTIEEQSNWCAAENVKNMKMLSDTNHDFGEKSKLFIPDLGILARSVWFVDTNKQVLYSEILKVQATEPNYDKVLDQVDQMN
>NZ_CP019323.1|WP_076614530.1|1125302_1125956_+|nitroreductase-family-protein
MGKNLIYKRRSIRSFDDEEVSDSLIEEIIKDASHAPSWQNAQPWHVYVAKDGVLDRIKAEYKNAKKNNLPSNTDITTPHRDNRSDLSMKNIEEWGDSVKEALGDQGTDLPEFQEARADLFHAPAVAYLTAKKNASEFTIYDIGSFGQTLMLSATSWGIGTIPAYALVTYPDILKKELLIPDDEEVVIGIAMGYPDDSKLNCIKTTRTDVDNILDIRK
>NZ_CP019323.1|WP_076614531.1|1125987_1126791_-|SPFH/Band-7/PHB-domain-protein
MFGIKIVHQNHKGLVELLGKYHHSVEAGLHFYIPIIERIYSVSLAMNPLRLPDYSIITKDNAEVRASLTLNYHTTDAVKYKYENTDSVESMSQLVRGHLRDIIGRMDLNEALGSTSKINQELAAAIGDLTNTYGVNVDRINIDELKPSTSIQDSMDKQLKADRERVAAIAKAEGEAKSIELTTKAKNEALIATADAQAKATRTRADAESYRITQMNEILNQAKSGYFENQSIEAFKELANSPTNTVVVSGDKIGEMGKIPVIKKMLE
>NZ_CP019323.1|WP_076614532.1|1126815_1127139_-|Arc-family-DNA-binding-protein
MADKKFLLRLDEDLYQKVAKRAEADNRSVNKYIVHLLQNNTKETTFENRQFVGQTIKGSDILTESGLVNVSGIYYRYIIADSTQVDPTGLYTILGATGNILTLQQVK
>NZ_CP019323.1|WP_076614533.1|1127202_1127718_+|GNAT-family-N-acetyltransferase
MHLIGKKVIIRNFEEGDFDSFYVLVKNKANHDLSGMEYTTDINEAKKIFYRYMETPGSYCIALKESSLMVGIIELNERGMSGELQKTREVGFIIEGKYRRLGLASEAIELIIKYGFERLGLIELWASAEEDNIAPQKLLVKHNFKYIYEVNQALNFLGGDDKILRYYLLKG
>NZ_CP019323.1|WP_076614534.1|1127833_1128265_+|LPXTG-cell-wall-anchor-domain-containing-protein
MKKRQRTRKSLKLKKRIVGYFAIAVIVLGVVGGFSVNHVIAESTNNSNGSIARSEAVVANTDGLSGADGSNANVLLSDDNTGNNTGATVKDTSNVTPSVNVNNMSSYPQTGDAHEYGYIIMGFSILIGLFAFYTKKIRIFATD
>NZ_CP019323.1|WP_043023465.1|1128464_1129490_-|IS30-family-transposase
MTRIKNIISNQYHQLNLAERGRIEALRGLDWSIRRIAKALHRNPSTISRELRRGTTTQINANTRIFEQSYLAETGEAVYRKHRLNSCYRGLFDHCQTFCNALVTALKARPRMHSVDTFVHQFKTNYPGVVCPSTPTVYRYIDDQRLTIRNSDLPAKLRRRVKRPGTKHHRINKKNLGHSIEERPTVVQARQELGHWEGDLVKGKRVESEPALMTLTERVSRLEIIVKLPNYHADTCLKALQNTLYDYGTEYFKTITFDNGAEFSSLSQVAGTDIYFAHPYSPWERGTNENTNGLLREFFPKGRSLVLASLIDIQLAQDTLNNRLRRSLNYRCPADLMPELA
>NZ_CP019323.1|WP_076614535.1|1129621_1130467_+|WxL-domain-containing-protein
MKLSKNVLVGSLATTGMILGMVAPATTAFAATTSGLVGSDNKVTPTTDLKEGQDAGVLGGKDSDLAIAYDAGDGSTVGSATATSNANVTVVSGILTLDAVPDFGFGSGASGTTVNLKSNAATGDGVDGNNEGLLQVTESRSQTPGFTLSAQLGAFKDATTSDAVTTTSAFNLNLPKQGLVNAKGENIGKVGDQYTTGNVVSTGNDTSKTNIDGAATDVMDVSGDYTTGPISASYKDANSASLDIANGIGDGTAPGTAQSLKSEITWTLTAKPSTNAATPKA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP019323_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019323_12

1187770-1187895

Orphan

Consensus_repeat	Method
GAAGAAATTGTGTTTTGTATCGCGTTTCAGCAAGTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP019323_12

>merge|NZ_CP019323|12|1187770-1187895|CRISPRCasFinder
GAAGAAATTGTGTTTTGTATCGCGTTTCAGCAAGTTTGAGGATAAAAAAGAAAAGCACAAATTCTTTTGACCAGAAAAAAATAAGAAGAGAAGAAATTGTGTTTTGTATCGCGTTTCGGCAAGTTT

>NZ_CP019323|12|12|1187770-1187895|CRISPRCasFinder
GAAGAAATTGTGTTTTGTATCGCGTTTCAGCAAGTTT	GAGGATAAAAAAGAAAAGCACAAATTCTTTTGACCAGAAAAAAATAAGAAGA
GAAGAAATTGTGTTTTGTATCGCGTTTCGGCAAGTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019323.1\|WP_076614611.1\|1197039_1198434_+\|O-antigen-ligase-family-protein	unknown	unknown	gnl\|CDD\|372600
NZ_CP019323.1\|WP_076614612.1\|1198452_1199184_-\|WecB/TagA/CpsF-family-glycosyltransferase	unknown	unknown	gnl\|CDD\|224833
NZ_CP019323.1\|WP_076618722.1\|1188300_1190853_+\|YfhO-family-protein	unknown	unknown	gnl\|CDD\|370572
NZ_CP019323.1\|WP_076614609.1\|1194269_1195745_+\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|225646
NZ_CP019323.1\|WP_076614615.1\|1201840_1202659_+\|ammonia-dependent-NAD(+)-synthetase	unknown	unknown	gnl\|CDD\|234831
NZ_CP019323.1\|WP_076614614.1\|1200361_1201837_+\|nicotinate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|236426
NZ_CP019323.1\|WP_076614602.1\|1182075_1182366_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076614607.1\|1190950_1192459_+\|glycerol-kinase-GlpK	unknown	unknown	gnl\|CDD\|234594
NZ_CP019323.1\|WP_083685936.1\|1181212_1181344_+\|XkdX-family-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076614599.1\|1180759_1181200_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076614606.1\|1186341_1187679_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|181958
NZ_CP019323.1\|WP_076614598.1\|1178870_1180760_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076614603.1\|1182366_1183353_+\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|214760
NZ_CP019323.1\|WP_076614610.1\|1196259_1196961_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_CP019323.1\|WP_076614608.1\|1192493_1193999_+\|glycerol-kinase-GlpK	unknown	unknown	gnl\|CDD\|234594
NZ_CP019323.1\|WP_076614613.1\|1199242_1200307_+\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340831
NZ_CP019323.1\|WP_076614604.1\|1183600_1183855_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_083685937.1\|1183826_1184354_+\|DUF2335-domain-containing-protein	unknown	unknown	gnl\|CDD\|227650
NZ_CP019323.1\|WP_076614605.1\|1184586_1185582_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381315
NZ_CP019323.1\|WP_076614601.1\|1181761_1182076_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP019323.1\|WP_076614615.1\|1201840_1202659_+\|ammonia-dependent-NAD(+)-synthetase	gnl\|CDD\|234831	PRK00768, nadE, ammonia-dependent NAD(+) synthetase.	0
NZ_CP019323.1\|WP_076618722.1\|1188300_1190853_+\|YfhO-family-protein	gnl\|CDD\|370572	pfam09586, YfhO, Bacterial membrane protein YfhO. This protein is a conserved membrane protein. The yfhO gene is transcribed in Difco sporulation medium and the transcription is affected by the YvrGHb two-component system. Some members of this family have been annotated as glycosyl transferases of the PMT family.	4.47636e-167
NZ_CP019323.1\|WP_076614609.1\|1194269_1195745_+\|peptide-MFS-transporter	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	1.99796e-151
NZ_CP019323.1\|WP_076614614.1\|1200361_1201837_+\|nicotinate-phosphoribosyltransferase	gnl\|CDD\|236426	PRK09243, PRK09243, nicotinate phosphoribosyltransferase; Validated.	0
NZ_CP019323.1\|WP_076614610.1\|1196259_1196961_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	4.84653e-87
NZ_CP019323.1\|WP_076614607.1\|1190950_1192459_+\|glycerol-kinase-GlpK	gnl\|CDD\|234594	PRK00047, glpK, glycerol kinase GlpK.	0
NZ_CP019323.1\|WP_076614606.1\|1186341_1187679_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|181958	PRK09564, PRK09564, coenzyme A disulfide reductase; Reviewed.	5.41306e-111
NZ_CP019323.1\|WP_076614611.1\|1197039_1198434_+\|O-antigen-ligase-family-protein	gnl\|CDD\|372600	pfam13425, O-antigen_lig, O-antigen ligase like membrane protein.	4.01339e-59
NZ_CP019323.1\|WP_076614603.1\|1182366_1183353_+\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|214760	smart00644, Ami_2, Ami_2 domain.	7.15607e-09
NZ_CP019323.1\|WP_076614608.1\|1192493_1193999_+\|glycerol-kinase-GlpK	gnl\|CDD\|234594	PRK00047, glpK, glycerol kinase GlpK.	0
NZ_CP019323.1\|WP_076614613.1\|1199242_1200307_+\|glycosyltransferase-family-4-protein	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	3.18698e-49
NZ_CP019323.1\|WP_076614612.1\|1198452_1199184_-\|WecB/TagA/CpsF-family-glycosyltransferase	gnl\|CDD\|224833	COG1922, WecG, Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane].	1.8279e-91
NZ_CP019323.1\|WP_083685937.1\|1183826_1184354_+\|DUF2335-domain-containing-protein	gnl\|CDD\|227650	COG5346, COG5346, Predicted membrane protein [Function unknown].	2.73264e-09
NZ_CP019323.1\|WP_076614605.1\|1184586_1185582_-\|aldo/keto-reductase	gnl\|CDD\|381315	cd19089, AKR_AKR14A1_2, AKR14A family of aldo-keto reductase (AKR). Escherichia coli L-glyceraldehyde 3-phosphate reductase (GPR/YghZ), also called GAP reductase, is a founding member of aldo-keto reductase family 14 member A1 (AKR14A1). It catalyzes the stereospecific, NADPH-dependent reduction of L-glyceraldehyde 3-phosphate (L-GAP). It is also involved in the stress response as a methylglyoxal reductase which converts the toxic metabolite methylglyoxal to acetol in vitro and in vivo. Salmonella enterica AKR is a founding member of aldo-keto reductase family 14 member A2 (AKR14A2). It catalyzes the conversion of 3-hydroxybutanal (3-HB) to 1,3-butanediol (1,3-BDO) by using NADPH as a cofactor.	4.56448e-132

>NZ_CP019323.1|WP_076614606.1|1186341_1187679_+|FAD-dependent-oxidoreductase
MKVSIIGCTHAGTFSAMNILKAHPDWEVSVFERNDNLSFLSCGIALWVSDRVSDPNKMFYSSPDDLAKLGAKMHMLHDVTSIDFDNKKLHVKNLENNEDFEQDYDKLVLTTGSSPIVPNIPGINSSRVQLCKNWTNATELKENAKNINSAIVIGAGYIGAELAEGYATLGKKTTLIDALPDVLAKNFDKNMSKVAEKDYIDNGVTLGLGEKVQAFEEVEDGVIVKTDKNEYKADVAVMSVGFRPNTDMYKDEFETLPNGALIVDKYMHTSKPDVFSAGDAASVFYNPTNDNQYIPLATNAVRQGILVGANIEKDTAEYIGTQSSSAVELFGRTYAASGLTAGHAKALGKKVETVSLEDNYRPEFMLSTTPVLMNLVWDPETRVIVGGALTSMYDVSQSANLLSLAIQKKVTIDELSMVDFFFQPNFDKPVNYVSALAIAAVEKAN
>NZ_CP019323.1|WP_076614605.1|1184586_1185582_-|aldo/keto-reductase
MYSASDNRYTNNFIRHAGNTGLMLPPISLGLWRHFGSADPLSDRRDVILHAFDKGIFHFDVANHYGDGQTGFGTSEELLGQILKDDLKSYRDELVISTKVGYEIHDGPYGIGTSRKSIIQGINDSLQRLNLDYVDVYYAHRYDDATPIEETVTALNDVVKSGKALYVGVSNYEVPELKKAIAMFKKLNTPFVLDQMSMNLLNNHVETSGLSQLLKDNGAGVIAYGPLCEGLLSERYLKGIPDSFNIHHTNKSLLDNGSDALVAKLNKLNELAKNRDQTLSQMSLAWLLRDPVVASVIIGTTNNDHLDENLQALNNLEFSSNEVEEINMLIK
>NZ_CP019323.1|WP_083685937.1|1183826_1184354_+|DUF2335-domain-containing-protein
MKNQNSMEHKENSTETDDATVTDNADESTVNSEIKATVDNFEKLAPKQREQVISKLEMYSGPIPHPDILKKYDDMYNGAAQEIIDNGVQESVHRRSMESEYLKQNTVRNRRRDWMGFLIGTLGIVFGFYLLYLGHTVVGSIFSGGTLVTLVSVFASNNNSESSEEEDNDGKDSEN
>NZ_CP019323.1|WP_076614604.1|1183600_1183855_+|hypothetical-protein
MTKLFKGLNNIIFNVNKQVSSIAFDTLRITKSDNSSLKSHIVINSSYSNSKQKEKNAIKSDFDAIGKDLFKSLKQYEKSKFNGA
>NZ_CP019323.1|WP_076614603.1|1182366_1183353_+|N-acetylmuramoyl-L-alanine-amidase
MFNPNVIKMNHVLSGDQGDARVAQKKYIIVHESGNDKDTKYADMLSNEVTFMHNNYSSAYTTHFVGYMDTSNEAQIYQIGTPGYVSWGALSANPYAPVQIEFARVYQNDRAKFKQAYHLYIEAIRYYAGLYEIPLKLDEAGNGVKSHQWITNNYGGDHQDPYAYFASMGISKSQFKHDVENGIDEVVQDTKVNRTTITIQNGPKSGIAGWTLEGKIIPGSNSKLVNGSSWLSNGLKKINGLPMYKIANDEYIPKKYTDQAGIVTINGVGGISSVTSTGEKNIGSESKFQDLTQWKTTDKLYQIAGRYYFKVATDEYIDAFYTIGGGNK
>NZ_CP019323.1|WP_076614602.1|1182075_1182366_+|hypothetical-protein
MDIIQNLNLINATELILIALICYGLTQAAKQSKLKSTYMPFISMVVGAFVGIIVALIMHDSELGKAGIVGFLVGGWTSGLFTGVKAVINDKKEILK
>NZ_CP019323.1|WP_076614601.1|1181761_1182076_+|hypothetical-protein
MTDIVVAVVSAIGGGVMTGFFNVWQAKLKNQGSNESVYADHTKELFERLDQITQERDDLKDQVNDLQLKIDYQSNIIEKQGKTIDALNKQMGELNSKFDLWEES
>NZ_CP019323.1|WP_083685936.1|1181212_1181344_+|XkdX-family-protein
MINLLKMEFGWGTLKKEDITGYIPAVISKEDFKTITGDDFTDD
>NZ_CP019323.1|WP_076614599.1|1180759_1181200_+|hypothetical-protein
MTKVALMLDDNRNITNFAEYPYSLNQDTSKGWILVESDPAFNISDISNWTIRGSDNKLVHISSNQTPDEENQNAITELTKQGLNQVLTVGQIQSAVTEVTKQNLDLARDNIQLKQDKTDMQSAITELTKQVITLSTPVSTTETTTK
>NZ_CP019323.1|WP_076614598.1|1178870_1180760_+|hypothetical-protein
MATSNKLTRTARVASHAFLSAQYEDKKGNVVVSKPVGDGNTLDLATIFKNSGFSGGTSGGNSGTGGNDGGDDINPPSAGDDIYPGDVTKGEVTKRYPIWSGNQNITETTPIEVNQPLDQVFANYDGLQFDVSLNKVTHLGDSSSDSINVQPTNTDNQDNQFSTSIPIPISIESNTFLNKKKVTIPLTGNADNKIIHVSKLTNTGIIPITAAELQSESTVPGLGAGYTNMPKTTNVSISATAVYRNLTSITENADRSSEEIVVYKDDVIYSVGQPGCQFMTIDGLIPNTNYASNQFSFCYRNSISKIESTHVGIQAFTTREITNVSAIPATIVFDTVNIKSYSYAHGFGFFYQQLQQGYSLALFDADNKIIAKGIPGVPFVSIDGLDAESSYKGLGISVGLICSEDLPKDSVVSAPSITIEYTNDQSLTISSTNGITKLADGTDKQDYSVSLSGINTFKKQSSVSQMANSYLFVGNSDKVDFTNIDSNFDNIDDGLEICLVEKIVTAPGYRTTLDELGLPSKFRISKKKLLSAMNSYDLFDKYFAMEKAHYPKSIESLENGIWKSYSGDVNVGIAGTKCNLKISNSTLTIDSDFKAATSVMSPNLSSILNSSNAVQFKIASVKTYKEEAK
>NZ_CP019323.1|WP_076618722.1|1188300_1190853_+|YfhO-family-protein
MKKNRILYYIGAFGINLAIISVIFWINGLVPFGNYNFLTSDLGTQYIAFLTELRRQLVSGNFHLYLFSQSLGDNFFPIISYYLLSPFNLLLVFFKAQSVPIAADVIIMLKISTMGVTMAYFFKQYFKQSNPSNYIFTVAYGFCGFVASYFYDLMWLDALIMLPIVAVGVMRVIQQHKYVLYYFSILLSIIFNYYLGYMLCIFSVCFFIYLALENNLMKQSNRFVIIRNYLITSILAGLSSAVVLVPTFAGMLKTAKTSFDGFNYLPSASFGFEAFTQLGIGGNTFTQRLQHGPSVFMTSTILILLLSYFFSDRVEKIDKNHSLFLIGILLASMFITTFNTIWHMFQNPAGFPFRNSFIFSFACIFIARKAFSAGVFKDTSTIIKATCTAGGLISIGYATEWLIPRFIERMGYERPDNEYNSYYFWLSLICIVISGFLIYLFQKNHYFGILILLMVSFEGFSNFNSVLGTAYLGDQRVYSHQYSRENDILEDVKHSSHPGHRIVVSKSGLNKAFPEQYNNYNDPILFNINGLSLYSSTLNQDTMMMMNNLGYFSLNVRRVSYFGGTALTNALYGVYFDVSQLNKLYKVNENYDAPTLGFLVNKDVYDFQMIPNRALDNQNRLWQDLNGNNTEYLKNASIQNMSQEDVKKRTKYIYQLKTEARGPLYFYVSPFNYYSSKIYVNGKRISTPQIKVQKSAVMDLGDFKKNESVKVEILTSNPLEINPSYFRTLDSKVFEPTVDKFRANSMKISSDLNHDTIKGTIKVKDASPLLLSVPYDNGWSAYDNGRKVEIHKVVSDLMAIDLSKGYHKIELKYQVPGLKLGWIISITSMITFALYFGYDKYKNKNKSQVK
>NZ_CP019323.1|WP_076614607.1|1190950_1192459_+|glycerol-kinase-GlpK
MLNEYIMAIDEGTTSTRAIIFDKQGSKVADAQREFTQHFPEPGWVEHDANEIWNAVQSTIANVFIESGVKPNQIAGIGITNQRETTVIWDKETGLPIYNAIVWQSRQTTDIANKLKKDGYDDLIHEKTGLLIDSYFSATKIRWILDHVKGAQERAERGELLFGTIDSWLLWKLSGGATHVTDYSNASRTMLFNIHDLKWDKDILKILNIPEAMLPTVRPNSEVYGKTKDYHFYGSEVPISGMAGDQQAALFGQMAFEPGMVKNTYGTGAFVVMNTGETPQLSDNNLLTTIGYGINGKVYYALEGSIFVAGSAIQWLRDAMKLVDSAPESEEAAKSSTDNDEVYVVPAFTGLGAPYWDSDARGAVFGLTRGTTREDFIKATLQSLAYQSRDVIETMKKDTGIDIPTLKVDGGAANNKYLMQFQADIIQTPVQRAKDLETTALGAAFLAGLAVGYWKDLDEIKKDYATGAIFKPSMDKDRADYLYEGWQQAVSATRQFKHKAIK
>NZ_CP019323.1|WP_076614608.1|1192493_1193999_+|glycerol-kinase-GlpK
MDKEQYVLAIDEGTTTTRAIIFDHTGKKIVAARHPIRQIMPNPGWVEHDATEIWNAVQTTIATALIESGIKPDQINSIGIASQRETSVIWDKKTGLPIHNAIVWQSRQTSKLANELIKDGYEDEIHQKTGLIVSPYFSATKIRWILDHVDGAQERAENGELLFGTINTWLLWQLTDGQSFLTDYSNASRTMLFNINDLKWDTSLLKLFNIPEKMLPEVRSNSELFGTTKNYHFYGSEVPITGMIGSQQASLFGQMAFEPGMVKNTYGTGAFAVMNTGNKPALSDNNLLTTIAYGINGEIKYALEGSIFVAGGALQWLRDGMRMIKNTPDTDAFAKKSTSQDEVYVVPAFSGLGAPYWDDAAHGTVFGITRGTTNDDFIKATLQAIAYQTKDIIDTMNSDSGIPIEVLKVDGAATKNDYLMKFQSDLLGIPLQVSSELETTSLGAAFLAGLGNGYWKDIEDIKKNYKTGTVYEPDMDEKTRDNLYDGWKEAVNATMAFKHHR
>NZ_CP019323.1|WP_076614609.1|1194269_1195745_+|peptide-MFS-transporter
MDDKKKDRGFFGQPIGLRTLFLTEFWERFSYYGMRAILLFYMYYAIDKGGLGMNQVTAASVMSIYGSLVYMSSVIGGYISDRILGARRTVFWGGVLIMLGHIALSFPLGESGLFLSIGLITIGTGLLKPNVSEMVGGLYTDDDPRRDSGFSIYVMGINLGSLIAPQAVSVMWHSFSFHAGFSLAAIGMFIGLIVYWWDGKNLPDTSLKAPDPISGPELKQFYRRVTYGVVAIIIIVAIMAFASALTVDNFIIILSVLGIALPVGYFVMMLTSKKVTKIERSRVVAYIPLFIAAAIFWAIEEQGSVVLALFAAEQTQLHFANFSISAPQFQMLNPFFIIIYSPIFAWLWLKLGKRQPSSPSKFWMGLVATAVSYFVLMIPLVGLSPAGKVNPLWLVLSWGIIEIGEMLISPVGLSATTKLAPKAFSSQMMSMWFLADSAGQAANAQLVKLFEPGNPSNEMMFFGVTGIVTLVVGVLLAILVPKIKPLMKGVN
>NZ_CP019323.1|WP_076614610.1|1196259_1196961_+|GntR-family-transcriptional-regulator
MRVPVYIQIHNRIKKEIESGKWAVGERIPSERKLAEDFDVSRMTLRQAIQTLVDEGILQRQVGSGTYVSSSKVQEKMFGTTSFTEITEGQGKKPSSKTVSYHTADPSMSEMEKLKLADGDQVLRMERIRYADDQPICFEVTTIPLSIVSNLNKEDITSSLYKALENKAELRLGSATQTVSAMLASEKIATLLSVKRGSAILRLRQVTTLDDGRPFEYVRSQYAGDRFEFYLER
>NZ_CP019323.1|WP_076614611.1|1197039_1198434_+|O-antigen-ligase-family-protein
MQSFVKKYSIFLMLYIVFQPILDSITGLMMRLNMDVTFGVFIRMIVMAVTVFYLLIYLILNLDNKRGFMIIGYFVLLALMSVINLYINYRTKTLFVASLEITTLAKSLYYPIMLLGYFFTFEELAEDRVINKYFPKVIFYAVNLITIIMIVAHFTNTAFSSYSYYKLGESGWFYAANELSAIVSITIPIMIWYALEKIDTLTRVYYWITIILAVYSALLIGTKGSLIAIICGICMGILATVVQFFRRGSNKKLLAGLCGLLVITLGGIFVAYPAMAVSRTAELHTEMIKYKKKQAKTKKGITKDQEKYVKTNKTVSYLLSGRTVYFETAAHNFQKATPAQKIFGMGYATNFKKVKDAKLVEMDYIDIFFQFGFLGTIVYMAPLVYCLVYLIGLFFRKFKYMWSFKWSLLVASVALGFGMALLTGHVIEAPSVSIYFVTILAYAMFNARVFFRTNEDPDTIGVEK
>NZ_CP019323.1|WP_076614612.1|1198452_1199184_-|WecB/TagA/CpsF-family-glycosyltransferase
MHKNRINILGTEFDNFTEKQFQKYLSDDMDARSNKFIVTANPEMVLSAQKNPKFSKVINSADYVIPDGIGIIKGAKTLGTPMHERITGFDTLMYLIKTANRKQLKVYLLGAKEEVIKASAKRIEREYPQIDLVGYHDGYFKDNQIVIDEIVQKKPNVILVALGYPKQEFFIDEYRKNIDAIWIGVGGSFDVFSGTKKRAPGIFQKLNLEWLYRLIKEPTRIGRMLAIPKYMRLIKKEKKNAEN
>NZ_CP019323.1|WP_076614613.1|1199242_1200307_+|glycosyltransferase-family-4-protein
MRVLHINAGNEDGGARTYIVNLMKGQQVTHTESSLLTFEDGPVAKMARENGLKVAVMPQKQRFDLSILKPLVTYINNNQIDIVHTHGPRANYIVSMIHKKINAKWAITVHSDPRIDFSGLKGKVMLNLNLHALKKADFLFYMNPDLKLYFEKLKIPDNKLFEVFNAIDFSHSNPLPIKHLTFSILEVARLVEVKNHELLLNALSKVKFNYRLTLVGDGPRMSELQKMSKDLGIDDKVDFVGFKEHTGDYYEDCDISVLTSRSESLPTVYLESAYYGRPVIATNVGATNKIINNETGWLIDSENEEQLIDALYDAYTNWKNDTLNQLGLALYQESRENYSIEKLAELVDQGYKQI
>NZ_CP019323.1|WP_076614614.1|1200361_1201837_+|nicotinate-phosphoribosyltransferase
MMTQYQDEGLTLHTDYYELNMMYTYWKKGLHNRNAVFECFFRSLPFDNGFAIFAGLDHVIDYLNNLKFSDSDIEYLREYGEFDEEFLSWLKDFKFSCTIRSAKEGDLVFNEEPIFQVEGPLAQCQLIETAVLNMINYQTLVATKAARIKTVCGDDPVLEFGSRRAQEVDAALWGSRASYIGGFDATSNVLAGKLFGIPISGTHAHALVQTYRNEYEAFKAYAETHKNCVFLVDTYDTLKSGVPNAIKVAKEMGDRINFQGVRIDSGDMAYISKRVREQLDEAGFTDAKVYASNDLDEKTILNLKMQGAKIDVWGIGTKNITAFDQPALGAVYKLVSIEDDRGNMMDTLKLSSNAVKISTPGKKQVWRITNNEKNNKSEGDYVTLWNENPREHSSLYMFHPQYTYINKTVEDFQAEPLLHDIFEDGKQIYTSPSVQDIRDYCAKNLDSLWDEYKRILNPQVYPVDLSSKLYSHKMKYIEKIRNDVNNIRIGD
>NZ_CP019323.1|WP_076614615.1|1201840_1202659_+|ammonia-dependent-NAD(+)-synthetase
MRPLQKEIIAYEGTKPVIDVDEEIRRSVDFLKNYLLKNKGLKSLVLGISGGQDSTLAGRLSQIAMTELRDETGDSDYKFIAVRLPYGEQADESDAMQAIEWMQADVVSRVNIKASVDALVRAVEENNYNITDFNKGNIKARTRMIAQYAIAGDNKGVVVGTDHAAENITGFFTKFGDGAADITPLFRLDKRQGRALLERLNAPKNLYEKTPTADLEEDRPSLPDELALGVSYTDIDNYLEGKDIPEKSAEIIENWYKKTAHKRRNPYTVFDK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP019323_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019323_13

1344989-1345061

Orphan

Consensus_repeat	Method
AGAAGAGAAGAAATTGTGTTTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP019323_13

>merge|NZ_CP019323|13|1344989-1345061|CRISPRCasFinder
AGAAGAGAAGAAATTGTGTTTTGAATCGCGTTTGGAGTAAGTTTGAGGACAGAAGATAAGAAATTGTGTTTTG

>NZ_CP019323|13|13|1344989-1345061|CRISPRCasFinder
AGAAGAGAAGAAATTGTGTTTTG	AATCGCGTTTGGAGTAAGTTTGAGGAC
AGAAGATAAGAAATTGTGTTTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019323.1\|WP_076614954.1\|1339237_1340161_-\|cysteine-synthase-A	unknown	unknown	gnl\|CDD\|273465
NZ_CP019323.1\|WP_076614945.1\|1336889_1337651_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP019323.1\|WP_076614979.1\|1346264_1347587_+\|branched-chain-amino-acid-transport-system-II-carrier-protein	unknown	unknown	gnl\|CDD\|283235
NZ_CP019323.1\|WP_076614938.1\|1335413_1336181_+\|recombination-regulator-RecX	unknown	unknown	gnl\|CDD\|237619
NZ_CP019323.1\|WP_076614971.1\|1343233_1344811_+\|peptide-chain-release-factor-3	unknown	unknown	gnl\|CDD\|179105
NZ_CP019323.1\|WP_083685950.1\|1354104_1354689_+\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
NZ_CP019323.1\|WP_076614966.1\|1341821_1343174_+\|HlyC/CorC-family-transporter	unknown	unknown	gnl\|CDD\|224173
NZ_CP019323.1\|WP_076614941.1\|1336265_1336799_+\|DUF402-domain-containing-protein	unknown	unknown	gnl\|CDD\|184219
NZ_CP019323.1\|WP_076614991.1\|1349771_1351058_+\|GntP-family-permease	unknown	unknown	gnl\|CDD\|225330
NZ_CP019323.1\|WP_076614957.1\|1340173_1340971_-\|homoserine-O-succinyltransferase	unknown	unknown	gnl\|CDD\|235433
NZ_CP019323.1\|WP_076614996.1\|1351076_1352225_+\|glycerate-kinase	unknown	unknown	gnl\|CDD\|376844
NZ_CP019323.1\|WP_076614975.1\|1345178_1346180_+\|choloylglycine-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|238303
NZ_CP019323.1\|WP_076614951.1\|1338374_1339160_-\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|270429
NZ_CP019323.1\|WP_076614999.1\|1352783_1354067_+\|RNA-polymerase-factor-sigma-54	unknown	unknown	gnl\|CDD\|274109
NZ_CP019323.1\|WP_076615003.1\|1354706_1355375_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367760
NZ_CP019323.1\|WP_076614987.1\|1348440_1349496_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|226355
NZ_CP019323.1\|WP_076614983.1\|1347572_1348415_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381364
NZ_CP019323.1\|WP_076615008.1\|1355583_1356387_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|369792
NZ_CP019323.1\|WP_076614948.1\|1337650_1338346_-\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_CP019323.1\|WP_076614962.1\|1341219_1341684_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP019323.1\|WP_076614954.1\|1339237_1340161_-\|cysteine-synthase-A	gnl\|CDD\|273465	TIGR01139, Cysteine_synthase, cysteine synthase A. This model distinguishes cysteine synthase A (CysK) from cysteine synthase B (CysM). CysM differs in having a broader specificity that also allows the use of thiosulfate to produce cysteine thiosulfonate. [Amino acid biosynthesis, Serine family].	2.41834e-154
NZ_CP019323.1\|WP_076614945.1\|1336889_1337651_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	4.50717e-116
NZ_CP019323.1\|WP_076614979.1\|1346264_1347587_+\|branched-chain-amino-acid-transport-system-II-carrier-protein	gnl\|CDD\|283235	pfam05525, Branch_AA_trans, Branched-chain amino acid transport protein. This family consists of several bacterial branched-chain amino acid transport proteins which are responsible for the transport of leucine, isoleucine and valine via proton motive force.	4.12832e-144
NZ_CP019323.1\|WP_076614966.1\|1341821_1343174_+\|HlyC/CorC-family-transporter	gnl\|CDD\|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	9.4581e-129
NZ_CP019323.1\|WP_076614971.1\|1343233_1344811_+\|peptide-chain-release-factor-3	gnl\|CDD\|179105	PRK00741, prfC, peptide chain release factor 3; Provisional.	0
NZ_CP019323.1\|WP_083685950.1\|1354104_1354689_+\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	8.95694e-65
NZ_CP019323.1\|WP_076614938.1\|1335413_1336181_+\|recombination-regulator-RecX	gnl\|CDD\|237619	PRK14135, recX, recombination regulator RecX; Provisional.	1.44081e-83
NZ_CP019323.1\|WP_076614941.1\|1336265_1336799_+\|DUF402-domain-containing-protein	gnl\|CDD\|184219	PRK13662, PRK13662, hypothetical protein; Provisional.	1.00167e-123
NZ_CP019323.1\|WP_076614991.1\|1349771_1351058_+\|GntP-family-permease	gnl\|CDD\|225330	COG2610, GntT, H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism].	1.24043e-51
NZ_CP019323.1\|WP_076614957.1\|1340173_1340971_-\|homoserine-O-succinyltransferase	gnl\|CDD\|235433	PRK05368, PRK05368, homoserine O-succinyltransferase; Provisional.	2.7709e-60
NZ_CP019323.1\|WP_076614996.1\|1351076_1352225_+\|glycerate-kinase	gnl\|CDD\|376844	pfam02595, Gly_kinase, Glycerate kinase family. This is family of Glycerate kinases.	0
NZ_CP019323.1\|WP_076614975.1\|1345178_1346180_+\|choloylglycine-hydrolase-family-protein	gnl\|CDD\|238303	cd00542, Ntn_PVA, Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins. PVA has an N-terminal nucleophilic cysteine, as do other members of the Ntn hydrolase family to which PVA belongs. This nucleophilic cysteine is exposed by post-translational prossessing of the PVA precursor. PVA forms a homotetramer.	1.62959e-100
NZ_CP019323.1\|WP_076614951.1\|1338374_1339160_-\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|270429	cd13711, PBP2_Ngo0372_TcyA, Substrate binding domain of ABC transporters involved in cystine import; the type 2 periplasmic binding protein fold. This subgroup includes cystine-binding domain of periplasmic receptor-dependent ATP-binding cassette transporters from Neisseria gonorrhoeae and Bacillus subtilis and their related proteins. Cystine is an oxidized dimeric form of cysteine that is required for optimal bacterial growth. In Bacillus subtilis, three ABC transporters, TcyJKLMN (YtmJKLMN), TcyABC (YckKJI), and YxeMNO are involved in uptake of cystine. Likewise, three uptake systems were identified in Salmonella enterica serovar Typhimurium, while in Escherichia coli, two transport systems seem to be involved in cystine uptake. Moreover, L-cystine limitation was shown to prevent virulence of Neisseria gonorrhoeae; thus, its L-cystine solute receptor (Ngo0372) may be suited as target for an antimicrobial vaccine. The cystine receptor belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.14268e-94
NZ_CP019323.1\|WP_076614999.1\|1352783_1354067_+\|RNA-polymerase-factor-sigma-54	gnl\|CDD\|274109	TIGR02395, RNA_polymerase_sigma-54_factor, RNA polymerase sigma-54 factor. A sigma factor is a DNA-binding protein protein that binds to the DNA-directed RNA polymerase core to produce the holoenzyme capable of initiating transcription at specific sites. Different sigma factors act in vegetative growth, heat shock, extracytoplasmic functions (ECF), etc. This model represents the clade of sigma factors called sigma-54, or RpoN (unrelated to sigma 70-type factors such as RpoD/SigA). RpoN is responsible for enhancer-dependent transcription, and its presence characteristically is associated with varied panels of activators, most of which are enhancer-binding proteins (but see Brahmachary, et al., ). RpoN may be responsible for transcription of nitrogen fixation genes, flagellins, pilins, etc., and synonyms for the gene symbol rpoN, such as ntrA, reflect these observations [Transcription, Transcription factors].	5.02791e-127
NZ_CP019323.1\|WP_076615003.1\|1354706_1355375_+\|hypothetical-protein	gnl\|CDD\|367760	pfam03992, ABM, Antibiotic biosynthesis monooxygenase. This domain is found in monooxygenases involved in the biosynthesis of several antibiotics by Streptomyces species. It's occurrence as a repeat in Streptomyces coelicolor SCO1909 is suggestive that the other proteins function as multimers. There is also a conserved histidine which is likely to be an active site residue.	0.000142971
NZ_CP019323.1\|WP_076614987.1\|1348440_1349496_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|226355	COG3835, CdaR, Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms].	3.69536e-66
NZ_CP019323.1\|WP_076615008.1\|1355583_1356387_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|369792	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase. This family contains haloacid dehalogenase-like hydrolase enzymes.	2.95663e-58
NZ_CP019323.1\|WP_076614948.1\|1337650_1338346_-\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	8.41719e-74
NZ_CP019323.1\|WP_076614983.1\|1347572_1348415_-\|aldo/keto-reductase	gnl\|CDD\|381364	cd19138, AKR_YeaE, Escherichia coli YeaE and similar proteins. Escherichia coli YeaE is the prototype of this family. It acts as an aldo-keto reductase (AKR) that catalyzes the reversible reduction of ketones to the respective alcohols using NAD(P)H as a hydride donor.	2.71889e-121

>NZ_CP019323.1|WP_076614971.1|1343233_1344811_+|peptide-chain-release-factor-3
MDQKQLNNEVKKRRTFAIISHPDAGKTTITEQMLYFGGVIRSAGTVKAKKSGQFATSDWMEIEKKRGISVTSSVMQFHYRDKDVNILDTPGHEDFSEDTYRTLMAVDAAVMVIDSAKGIEPQTKKLFKVVKKRGIPIFTFMNKLDRDGRDPLDLIAELEDLLNIEGCAMNWPIGMGKELKGLYDITNNRVELYRKEGDDRYLPLDENNKLPAGNDLEGEGVYDQAVGEVDLIKEAGNTFDIKKIQAGNQTPVFFGSALTNFGVQTFLDSFLDMAPAPGEHKMQNSDDIVKPDDTEFSAFVFKIQANMNPNHRDRIAFVRICSGEFEKGIDVTLQRTGKVMRLNNATEFMSDQREQVKSAVAGDIVGLYDTGNFQIGDTIYTGKKEVQFEDLPQFTPEMFMQVQAKNVMKQKSFHKGMQQLVQEGAVQLYRTYTTNDYILGAVGQLQFEVFQFRMKNEYNCDVVMNPIGSRTARWIDPEQLDPAMSSTRNMLVKDMEDQPLFLFENRFAENWFVNKYPDVKLSSKL
>NZ_CP019323.1|WP_076614966.1|1341821_1343174_+|HlyC/CorC-family-transporter
MSDDPTGATLTGQLILIVVLTFLNAFFAAGEMAIVSVNKTSVEEKAKDGNRKAIKILQAINHPNNFLSTIQVAITLAGFLSSASAATSLTGVMEGLIGKFPGSRELSIVIITIILSYFTLVLGELYPKRIALHSPYKVASATEPVVSIFGKILKPFVWLLTKSIDLLMKITPIDFSKKDDKVTRNEMMATIQKSRQSGTINSDEYQMLQGIIRFGDTTIREIMVPRIDTFMIDINDPIDKNIDAILSQPFSRIPVYGGDKDTIIGIVHIKNLLKKARESGFENITLKEIMTEPLFVQESTNIDSVLIKMRSTQTQIAMVVDEYGGIVGLATIEDLIEEIVGEIDDEYDEVTTNYRRLSSNKYSVIGRFSLEDFNDLFNEDLEAEDVDTIAGYLIANIGEIPDENHPKSFTLEDGLILTSDEMNGSRIEKVLVTLPDSKTKSVMANTFRNK
>NZ_CP019323.1|WP_076614962.1|1341219_1341684_-|hypothetical-protein
MSNKKITIIYILFFIIPYIICLLVVGVSYNALVLHALTWRVLVGGIVGSLGMFAVKVIAQRPVLIMYRSANRKSLKSLINFFILERSKVVIGLNLVFDFFLSLASIYIVAKVLTLQQIMGTTLGWLVLVLMVSLTLASYLEFETLSIYTEKKNK
>NZ_CP019323.1|WP_076614957.1|1340173_1340971_-|homoserine-O-succinyltransferase
MEHVKIGILNLMQEKIPTNQNFEHILKDESVDLTFYYSATRYVDRVLDTRITETMKPLDLSEISQFDGFIITGSPVEKLNFEQVTYIQEINELLDKLNQLNIPQLYICWGAMAAMDHFYQIKKSILPHKTFGIYQNNITNDTYLLHNVSNEFPAPHARYAEMNHQDIADNSSLEINAVSENGLLTLVTSKIRPQVFIFSHLEYPQNGLDDEYKRELASGKVPNAFPARNYYSPIDKHPMFTWKETQIQFFSNWLNCIKDTKLIKS
>NZ_CP019323.1|WP_076614954.1|1339237_1340161_-|cysteine-synthase-A
MTKIADNITELIGDTPIVKLNKVVPDDAADVYVKLEFFNPGSSIKDRIALAMIEDAEKSGKIKPGDTIVEPTSGNTGIGLSLVSAAKGYHLIIMMPDTMSVERRKLMQGYGTKLVLTPGSEGMGGAIKRAKDLAEEKGYFLPMQFTNPANPAIHEKTTGKEIIDAFGDDSIDAFVAGVGTGGTLSGVSHALTKKYPDITIYALEAAESPLLKEGKTGPHKIQGISAGMIPDTLDQDSYSDIVEVTSDQAIQTAQEVSKKEGFLPGISSGANIYGAIQIAKKLGKGKKVVTVAPDNGERYLSTDLFKF
>NZ_CP019323.1|WP_076614951.1|1338374_1339160_-|transporter-substrate-binding-domain-containing-protein
MKKRLVLLLTTIAALVLILTGCSSNKDATNTKTKGTLTVGLEGTYAPYSYREDGKLKGFEVDFARDIAKEMGLKVKFVPTKWDSLIAGLNSNTFDVVINNVAMNKSREKQYIFSTPYIYSRSALILKKDNTDIKNITDIKGKKVAAGTGTDNYNKAEKYGADIVPSSDFQTSMSMIDQGRVVAAVNSKEAFLTWKKDHKNTDLKYQVISSKYIAASKIAPIYNKKSTGLRNDVNKAIKKLYKDGTMKKLSIKYFGEDITKK
>NZ_CP019323.1|WP_076614948.1|1337650_1338346_-|amino-acid-ABC-transporter-permease
MWHIIISSLPEMIGAMLQFTIPLAIISFIFGLILAVLTALIKFIQPSENKALKYPWLVLRAIANFYVWLFRSTPLLVQLFIIFFGLPSVGIQLPAFIAAVIGFSLNTGAYASETIRSALLSVPQDQWDAAYTLNFTTRQTLMKIVLPQAVRIALPPLSNSFIGLVKDTSLASSITILEMFQVSQQITAKNYQPLLMYTLAAALYAIVCSLLSWLQHYLERRTSKYVKGGQN
>NZ_CP019323.1|WP_076614945.1|1336889_1337651_-|amino-acid-ABC-transporter-ATP-binding-protein
MLSAKHINKQYEGKTVLNDISVDFPDGKTTVILGPSGSGKSTLLRSLDMLVRPESGTVSFPDLSIDYSRPISKKDSFDLRRKTSMVFQNWNLFPNLTVIDNITTAPITVLKRSKEDAQTLAKSLIKEVGLAGLEDRYPSQLSGGQQQRISICRALAMNPEYILLDEPTSALDPELETQVLRILEKLCQQGQSMVIVTHNMEFARLVSDKIVFIEDGNKIYDGSTKEFFGNPTPRTKEFLSGISLDEENDKINQ
>NZ_CP019323.1|WP_076614941.1|1336265_1336799_+|DUF402-domain-containing-protein
MQIPKEGDYVAIQSYKHDGHLHRTWRETMVLKTSENEIIGCNENTLVTESDGRRWVTREPALVYFHKHYWFNIITMIRESGVSYYCNLATPFALDKEAIKYIDYDLDVKVFPDGEKRLLDVDEYAAHSKMWNYPPEIDAILHRNVDILIDWIDKGKGPFSQSYVDLWMQRYEELSHH
>NZ_CP019323.1|WP_076614938.1|1335413_1336181_+|recombination-regulator-RecX
MAKVTKIQAQKRKGRYNVYLDGEYSFPVSETTLVDYRLMNGLELDDAQIKEIKSRENINKAYGDAVNYLSYELRTEKEMRDYLYKKEYSSPVVFSVMERLQKLNYMDDNAYAVSFINTQLNTTANGPKVIRQKMIQKGVPATIIEDKLSEIDQDKLLENATVFAGKQVRKQRHKSFQQMMTKLKQGLYQKGYSGEIISQAIDDLELERDDESETENLQLLVEKVKHRYNNPAKLINYLMTKGYRYDAIKKVLKGE
>NZ_CP019323.1|WP_076614975.1|1345178_1346180_+|choloylglycine-hydrolase-family-protein
MCTGISYESTDNQEFFGRTQEYNLEYDYVLAQFPRDYVVDISASKWKTKYSVIGVSARIDHQLMPTVLDGLNEFGLACSTQYFAEDNIYNTMDEIIEEGKSPVYAEQFIFYILSMCKDIDDVKQILKSVAIPNSSIVQKTGLPQHFFIKDGSGRSIVVEPSIAAEFGFNVYENKIGVMTNSPSFDWQVTNLKNYTGLTTKFQNDLQLNNTTIKSLGKSSGLIGLPGDYTAPSRFVKATTLLNFSEKTDSNNSINLGFHILSMSDIPKGVVICADGTSEYTQYTSLYNQTKRELYIKLYDNLDVQKITFSDEYANNSEPKIYELVKESHYKELK
>NZ_CP019323.1|WP_076614979.1|1346264_1347587_+|branched-chain-amino-acid-transport-system-II-carrier-protein
MDKKLSWRNSLFIGSMLFGLFFGAGNLIFPVFLGQQAGSHVGLAISGFLITGIGLPLLGVAGMGMTRSSSVFELAEHVNKPFAYVFTILLYLTIGPLFATPRLATTSFQMGISPFVSSDNRRGFLIIFSIVFFIVAWLFARKPSNIMTYVGKWLTPTFLILLGILIVVALVKPMGNFSATPQGMYKKSPVLTGFTEGYNTMDALASLVFGVVVIDAIKELGITKPVQIAKETIKSGAISIILMGILYSLLAIIGTMSLGKLSLATNGGVTLAQIFKYYFGSVGSILLALIVIIACLKTAIGLISSFGDSMTEIFPKTNYQAMIALASVVSCVIANLGLTKLIKYSTPVLMFIYPLAIVMILLAVFSPIIGTSSKVYKTTLVFTIIPAVFSGMENLPKGLQVRSILSINQVLPFSSMGLGWIIPAFLGLIIGYILSKLDHV
>NZ_CP019323.1|WP_076614983.1|1347572_1348415_-|aldo/keto-reductase
MRQIQFNDQPTSIIGMGTWRIGEDPSKGSAEIQTIQYGLNHGITLIDTAEMYGEGAAETLVGEAIKDFDRQKFQLVSKFYPYHATPKLIKNSLEHSLKRLQTDYLDLYLLHWRGETPLAETISGLVDMKKAGYIKDFGVSNFDINDLKELYSVPNGDQCKVNQNLYNIGSRGIEYSILPWQKEHDISFMGYSPFGSDKNAYLHPQEIITDMANQKHITIFQLLLAWVIRNNDLLSIAKTSSLEHLKDNLGSIDVRFTDDELELLDKYYPAPTKETPLDVI
>NZ_CP019323.1|WP_076614987.1|1348440_1349496_-|helix-turn-helix-domain-containing-protein
MKLDPILAQSIVDRMMESIPYNINMMNEHGYIIASGDKNRLNTLHVGAVDAIEKSETLPMIQSFGTHGQPGVNIPVQFQSKTIGVIGITGDPKKVTPLASLLKISTELLITQSYNNQVEAQHKNRLNRFLYQWTEVTDDIKAQTELNIEAKLLQVDLFIQRFAIVVETADTTPLLIKKNDYTLALSPHSTVIITASDTAMNLYLKRAISKHIKVGVGNKTTLLGKSVKQAQSTIRVAQIFDFDNTNFYNQISLIDKILSTDLSTHEIIEQFNTLHQTDGGRELIDTLSCYFINNESVTETSKQLHIHRNTTNYRLNKISEYFGLDLHILDETFKLYLNYLFFQESVYKRTH
>NZ_CP019323.1|WP_076614991.1|1349771_1351058_+|GntP-family-permease
MAVIAWWAALIGLALAIILILFKVNPVYSLMMGSIIGCLLGGMSLAQTTNTIVTGSSGVMGTIIRVIAAGVLAGVMMESGAANVIATNIVSHFSDRLTILALALSTMVLTGVGIFIPVAVLIVAPIALEVGQKMHYSKLSLLVALSGGGKAGNIISPNPNTIAAAKGFNVELSQVMIADFVPAVVGLIVAVLLAMLVKNRGTFIPADQKFAKKEVEDLPSLGSAITTPLVAVVLLLITPIGDVLGIKALSSLNIDAMYILPIAGLIGTLAMKQQRKFLTYMKNGLARMTDVVMILIGAGAIAGLISASNLPQEIVMLVKSSGISGTFLAPIAGILMAGATGSTSTGVILASNSFSKSIMSLGISGTGAAAMVHTGATVIDQLPHGNYFHVTAQSVNMQFKERMSVVVWEMLVGLSMTIVATLMYGGLF
>NZ_CP019323.1|WP_076614996.1|1351076_1352225_+|glycerate-kinase
MKIVLAPDSFKNSLTAKQVASAMQTGLQRVYPDATFVKVPMADGGEGTVQSLVDAKNGQILTEKVINPLGVETQAHYGLIDDGSVAVIEMAEASGIQFINEYTRNPYVTTTYGTGQLMKAAIKHGAKTIIIGIGGSATNDGGAGMAQALGAHLLDADNNELKYGGAVLKKLSKIDISEMLPELNDIKIIVASDVTNPLTGKNGASHVFGPQKGANEEMVEFLDDALSHYAKVIKKDLGKDLEQTPGAGAAGGLGAGLLAFTNAKLQSGVDIVVNYTGLKDQVKDADLVFTGEGQIDFQTKFGKTPIGVSQATKEVNKNATVVAIAGSVGDRISELYPLGIDAIFTCVPGVQSLDKAISDSGKNIEQVCENVGRLFKSVTTRG
>NZ_CP019323.1|WP_076614999.1|1352783_1354067_+|RNA-polymerase-factor-sigma-54
MQLKQSHQLKQKQMQKLSLTQGMRQSIVMLQSDAIDLSEYLKDVSLENPLFDVHTSLDVPFMQGTRDNQSYQLRDNSQSLFEYLLDQVQLTMRDTPLRDLVIYLVEQLDPNGYLPITDKEIMDELNIDKVSLLDALTLLQQLDPPGVGAHDLRECLLLQAQADRESPEYAVDILKYYFDTMVDHDWQTIQNNLQIDKTTLDENIDYIKELSATPGERYNGSDLQYVVPELQVKNNDGKLSLAITRYGQPQLIFAQETYDLLSKTVDNDVKNYIKEKYDQYQTLEYNLERRIKTVSMIGKVIVQTQYKFFTQETTTLEPLLLRDVAQRLQLSESTVSRAINGKYIQTDFGMIELKNLFSRRSKVSDGVKSRSVDQVKDTIKKLIDEEDKPLSDQKISDLLKESGLEVARRTVAKYREQLHILTANKRK
>NZ_CP019323.1|WP_083685950.1|1354104_1354689_+|sugar-O-acetyltransferase
MMTEHEKLLAGLDYDYRDPELQGMIAHCKELVGIINTTTDFKKRQESVDNLFGVSGKGLTINGQISALYGEHIHVGDDVFINGNCTFQDSNIITLGSRVVIAPDTKLYCGEHAIDASKRFGVREDGSKYLITYTKPISIGDDVWIGGNVTIIGGVTIGNNVIVGAGAVVTKDVPDNTIVAGVPAKVIRSLEPLK
>NZ_CP019323.1|WP_076615003.1|1354706_1355375_+|hypothetical-protein
MEKLTQAPLFRLFNLKIDPINRTSFLDVGQNNLMTSIKNEVGTLAMYTGHLDSSGADNIVIELYKDQPSYEIHANSPQFAAFKKVAGKIVVDQSVTSLNPQLLLESTEPVQGIKQAEFVQLTELTIDDSSIDKFRILVSEKMKQDKSKSEVLVAYAGNDSADSTKWYLFEIYQNKSVYDDCQKEEYVKKYKEETKQMIKQTKNYTLNPDTVVNHGGLDFENK
>NZ_CP019323.1|WP_076615008.1|1355583_1356387_-|Cof-type-HAD-IIB-family-hydrolase
MIKQIFSDMDGTLLNDRGVISDMNIQTIKSCNIPFTLVSARSPIEMFDTIDVLGLTNTQIAFNGGLIYKRHGNSIDKISEDFLDSRVVENITLQMRQQFEDISLSLYTDEKWYTDKIDSGIKLETSLTFHEPEVVKYPEFFKNVDEDIYKIMFIANSISEMTTIIKALDDLHLTGVSIQQSGNNYLEITSDKAKKSAGIAYIQKLNHLEKSEMAAFGDGHNDIPMLKMTGTSIIMENATKEVKKYATHITKTNQQDGVSFGIMNFIK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP019323_14

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019323_14

2139682-2139799

Orphan

Consensus_repeat	Method
AAGTGATCTCGCCTAATTTAATAGTAACAACTCAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP019323_14

>merge|NZ_CP019323|14|2139682-2139799|CRISPRCasFinder
AAGTGATCTCGCCTAATTTAATAGTAACAACTCACCGTCTCATAAAAAAAGAGACCACCAGCATTTCGATAAATCGAAGTGCAAAGTGATCTCGCCTAATTTAATAGTAACAATTCAC

>NZ_CP019323|14|14|2139682-2139799|CRISPRCasFinder
AAGTGATCTCGCCTAATTTAATAGTAACAACTCAC	CGTCTCATAAAAAAAGAGACCACCAGCATTTCGATAAATCGAAGTGCA
AAGTGATCTCGCCTAATTTAATAGTAACAATTCAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019323.1\|WP_076618914.1\|2146101_2147055_-\|N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	unknown	unknown	gnl\|CDD\|271335
NZ_CP019323.1\|WP_076617352.1\|2136580_2138335_-\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|273055
NZ_CP019323.1\|WP_076617369.1\|2143970_2145320_-\|PTS-sugar-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|224372
NZ_CP019323.1\|WP_076617349.1\|2135119_2136544_-\|6-phospho-beta-galactosidase	unknown	unknown	gnl\|CDD\|184102
NZ_CP019323.1\|WP_076618911.1\|2143427_2143946_-\|glycine/betaine/sarcosine/D-proline-family-reductase-selenoprotein-B	unknown	unknown	gnl\|CDD\|377820
NZ_CP019323.1\|WP_076618908.1\|2139886_2141197_-\|Sapep-family-Mn(2+)-dependent-dipeptidase	unknown	unknown	gnl\|CDD\|349884
NZ_CP019323.1\|WP_076617362.1\|2141220_2142333_-\|M42-family-metallopeptidase	unknown	unknown	gnl\|CDD\|349906
NZ_CP019323.1\|WP_076617385.1\|2150150_2151311_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|226925
NZ_CP019323.1\|WP_076617339.1\|2131828_2133568_-\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|273055
NZ_CP019323.1\|WP_120270405.1\|2147308_2148643_+\|guanine-deaminase	unknown	unknown	gnl\|CDD\|238628
NZ_CP019323.1\|WP_076618905.1\|2129977_2130568_-\|dihydroxyacetone-kinase-subunit-L	unknown	unknown	gnl\|CDD\|274099
NZ_CP019323.1\|WP_076617342.1\|2133605_2133953_-\|PTS-lactose/cellobiose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|238133
NZ_CP019323.1\|WP_076617336.1\|2130593_2131586_-\|dihydroxyacetone-kinase-subunit-DhaK	unknown	unknown	gnl\|CDD\|237724
NZ_CP019323.1\|WP_076617380.1\|2148629_2149973_+\|purine/pyrimidine-permease	unknown	unknown	gnl\|CDD\|274468
NZ_CP019323.1\|WP_076617358.1\|2138734_2139589_-\|PRD-domain-containing-protein	unknown	unknown	gnl\|CDD\|170086
NZ_CP019323.1\|WP_076617354.1\|2138350_2138704_-\|PTS-lactose/cellobiose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|129903
NZ_CP019323.1\|WP_076617372.1\|2145346_2146063_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_CP019323.1\|WP_076617332.1\|2129605_2129974_-\|PTS-dependent-dihydroxyacetone-kinase-phosphotransferase-subunit-DhaM	unknown	unknown	gnl\|CDD\|184702
NZ_CP019323.1\|WP_076617345.1\|2133967_2134822_-\|PRD-domain-containing-protein	unknown	unknown	gnl\|CDD\|170086
NZ_CP019323.1\|WP_076617366.1\|2142346_2143411_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|349906

Protein	Function_ID	Function_description	E-value
NZ_CP019323.1\|WP_076618914.1\|2146101_2147055_-\|N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	gnl\|CDD\|271335	cd04513, Glycosylasparaginase, Glycosylasparaginase and similar proteins. Glycosylasparaginase catalyzes the hydrolysis of the glycosylamide bond of asparagine-linked glycoproteins. This enzyme is an amidase located inside lysosomes. Mutation of this gene in humans causes a genetic disorder known as aspartylglycosaminuria (AGU). The glycosylasparaginase precursor undergoes autoproteolysis through an N-O or N-S acyl rearrangement of the peptide bond, which leads to the cleavage of a peptide bond between an Asp and a Thr. This proteolysis step generates an exposed N-terminal catalytic threonine and activates the enzyme.	2.45731e-122
NZ_CP019323.1\|WP_076617352.1\|2136580_2138335_-\|PTS-transporter-subunit-EIIC	gnl\|CDD\|273055	TIGR00394, lac_pts_IIC, phosphotransferase system, lactose specific, IIC component. This family of proteins models the IIC domain of the phosphotransferase system (PTS) for lactose. The IIC domain catalyzes the transfer of a phosphoryl group from the IIB domain to lactose. When the IIC component and IIB components are in the same polypeptide chain they are designated IIBC. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS].	0
NZ_CP019323.1\|WP_076617369.1\|2143970_2145320_-\|PTS-sugar-transporter-subunit-IIC	gnl\|CDD\|224372	COG1455, CelB, Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism].	8.2004e-141
NZ_CP019323.1\|WP_076617349.1\|2135119_2136544_-\|6-phospho-beta-galactosidase	gnl\|CDD\|184102	PRK13511, PRK13511, 6-phospho-beta-galactosidase; Provisional.	0
NZ_CP019323.1\|WP_076618911.1\|2143427_2143946_-\|glycine/betaine/sarcosine/D-proline-family-reductase-selenoprotein-B	gnl\|CDD\|377820	pfam07355, GRDB, Glycine/sarcosine/betaine reductase selenoprotein B (GRDB). This family represents a conserved region approximately 350 residues long within the selenoprotein B component of the bacterial glycine, sarcosine and betaine reductase complexes.	4.20162e-20
NZ_CP019323.1\|WP_076618908.1\|2139886_2141197_-\|Sapep-family-Mn(2+)-dependent-dipeptidase	gnl\|CDD\|349884	cd03888, M20_PepV, M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides. Peptidase M20 family, Peptidase V (Xaa-His dipeptidase; PepV g.p. (Lactobacillus lactis); X-His dipeptidase; beta-Ala-His dipeptidase; carnosinase) subfamily. The PepV group of proteins is widely distributed in lactic acid bacteria. PepV, along with PepT, functions at the end of the proteolytic processing system. PepV is a monomeric metalloenzyme that preferentially degrades hydrophobic dipeptides. The Streptococcus gordonii PepV gene is homologous to the PepV gene family from Lactobacillus and Lactococcus spp. PepV recognizes and fixes the dipeptide backbone, while the side chains are not specifically probed and can vary, rendering it a nonspecific dipeptidase. It has been shown that Lactococcus lactis subspecies lactis (L9) PepV does not hydrolyze dipeptides containing Pro or D-amino acids at the C-terminus, while PepV from Lactobaccilus has been shown to have L-carnosine hydrolyzing activity. The mammalian PepV also acts on anserine and homocarnosine (but not on homoanserine), and to a lesser extent on some other aminoacyl-L-histidine dipeptides. Also included is the Staphylococcus aureus metallopeptidase, Sapep, a Mn(2+)-dependent dipeptidase where large interdomain movements could potentially regulate the activity of this enzyme.	1.27884e-136
NZ_CP019323.1\|WP_076617362.1\|2141220_2142333_-\|M42-family-metallopeptidase	gnl\|CDD\|349906	cd05656, M42_Frv, M42 Peptidase, endoglucanases. Peptidase M42 family, Frv (Frv Operon Protein; Endo-1 4-Beta-Glucanase; Cellulase Protein; Endoglucanase; Endo-1 4-Beta-Glucanase Homolog; Glucanase; EC. 3.2.1.4) subfamily. Frv is a co-catalytic metallopeptidase, found in archaea and bacteria, including Pyrococcus horikoshii tetrahedral shaped phTET1 (DAPPh1; FrvX; PhDAP aminopeptidase; PhTET aminopeptidase; deblocking aminopeptidase), phTET2 (DAPPh2) and phTET3 (DAPPh3), Haloarcula marismortui TET (HmTET) as well as Bacillus subtilis YsdC. All of these exhibit aminopeptidase and deblocking activities. The HmTET is a broad substrate aminopeptidase capable of degrading large peptides. PhTET2, which shares 24% identity with HmTET, is a cobalt-activated peptidase and possibly a deblocking aminopeptidase, assembled as a 12-subunit tetrahedral dodecamer, while PhTET1 can be alternatively assembled as a tetrahedral dodecamer or as an octahedral tetracosameric structure. The active site in such a self-compartmentalized complex is located on the inside such that substrate sizes are limited, indicating function as possible peptide scavengers. PhTET2 cleaves polypeptides by a nonprocessive mechanism, preferring N-terminal hydrophobic or uncharged polar amino acids. Streptococcus pneumoniae PepA (SpPepA) also forms dodecamer with tetrahedral architecture, and exhibits selective substrate specificity to acidic amino acids with the preference to glutamic acid, with the substrate binding S1 pocket containing an Arg allows electrostatic interactions with the N-terminal acidic residue in the substrate. The YsdC gene is conserved in a number of thermophiles, archaea and pathogenic bacterial species; the closest structural homolog is Thermotoga maritima FrwX (34% identity), which is annotated as either a cellulase or an endoglucanase, and is possibly involved in polysaccharide biosynthesis or degradation.	3.11971e-123
NZ_CP019323.1\|WP_076617385.1\|2150150_2151311_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|226925	COG4552, Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases [General function prediction only].	6.95567e-45
NZ_CP019323.1\|WP_076617339.1\|2131828_2133568_-\|PTS-transporter-subunit-EIIC	gnl\|CDD\|273055	TIGR00394, lac_pts_IIC, phosphotransferase system, lactose specific, IIC component. This family of proteins models the IIC domain of the phosphotransferase system (PTS) for lactose. The IIC domain catalyzes the transfer of a phosphoryl group from the IIB domain to lactose. When the IIC component and IIB components are in the same polypeptide chain they are designated IIBC. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS].	0
NZ_CP019323.1\|WP_120270405.1\|2147308_2148643_+\|guanine-deaminase	gnl\|CDD\|238628	cd01303, GDEase, Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and therefore can play a role in the regulation of cellular GTP and the guanylate nucleotide pool.	2.84489e-145
NZ_CP019323.1\|WP_076618905.1\|2129977_2130568_-\|dihydroxyacetone-kinase-subunit-L	gnl\|CDD\|274099	TIGR02365, dha_L_ycgS, dihydroxyacetone kinase, phosphoprotein-dependent, L subunit. Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form (EC 2.7.1.-) with a phosphoprotein donor related to PTS transport proteins. This family represents the subunit homologous to the E. coli YcgS subunit.	1.13201e-68
NZ_CP019323.1\|WP_076617342.1\|2133605_2133953_-\|PTS-lactose/cellobiose-transporter-subunit-IIA	gnl\|CDD\|238133	cd00215, PTS_IIA_lac, PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation. This family of proteins normally function as a homotrimer, stabilized by a centrally located metal ion. Separation into subunits is thought to occur after phosphorylation.	8.64566e-35
NZ_CP019323.1\|WP_076617336.1\|2130593_2131586_-\|dihydroxyacetone-kinase-subunit-DhaK	gnl\|CDD\|237724	PRK14481, PRK14481, dihydroxyacetone kinase subunit DhaK; Provisional.	0
NZ_CP019323.1\|WP_076617380.1\|2148629_2149973_+\|purine/pyrimidine-permease	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	1.55112e-85
NZ_CP019323.1\|WP_076617358.1\|2138734_2139589_-\|PRD-domain-containing-protein	gnl\|CDD\|170086	PRK09772, PRK09772, transcriptional antiterminator BglG; Provisional.	9.38599e-27
NZ_CP019323.1\|WP_076617354.1\|2138350_2138704_-\|PTS-lactose/cellobiose-transporter-subunit-IIA	gnl\|CDD\|129903	TIGR00823, PTS_system_lactose-specific_IIA_component, phosphotransferase system enzyme II, lactose-specific, factor III. The PTS Lactose-N,N?-Diacetylchitobiose-b-glucoside (Lac) Family (TC 4.A.3)Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains.The Lac family includes several sequenced lactose (b-galactoside) permeases of Gram-positive bacteria as well as the E. coli N,N?-diacetylchitobiose (Chb)permease which can transport aromatic b-glucosides and cellobiose as well as the chitin disaccharide, Chb, but only Chb induces expression of the chboperon. While the Lac permeases consist of two polypeptide chains (IIA and IICB), the Chb permease of E. coli consists of three (IIA, IIB and IIC). In B. subtilis, a PTS permease similar to the Chb permease of E. coli is believed to transport lichenan (a b-1,3;1,4 glucan) degradation products, oligosaccharides of 2-4 glucose units. This model is specific for the IIA subunit of the Lac PTS family. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	9.0066e-36
NZ_CP019323.1\|WP_076617372.1\|2145346_2146063_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	3.32131e-61
NZ_CP019323.1\|WP_076617332.1\|2129605_2129974_-\|PTS-dependent-dihydroxyacetone-kinase-phosphotransferase-subunit-DhaM	gnl\|CDD\|184702	PRK14484, PRK14484, phosphotransferase mannnose-specific family component IIA; Provisional.	2.84307e-41
NZ_CP019323.1\|WP_076617345.1\|2133967_2134822_-\|PRD-domain-containing-protein	gnl\|CDD\|170086	PRK09772, PRK09772, transcriptional antiterminator BglG; Provisional.	1.211e-33
NZ_CP019323.1\|WP_076617366.1\|2142346_2143411_-\|hypothetical-protein	gnl\|CDD\|349906	cd05656, M42_Frv, M42 Peptidase, endoglucanases. Peptidase M42 family, Frv (Frv Operon Protein; Endo-1 4-Beta-Glucanase; Cellulase Protein; Endoglucanase; Endo-1 4-Beta-Glucanase Homolog; Glucanase; EC. 3.2.1.4) subfamily. Frv is a co-catalytic metallopeptidase, found in archaea and bacteria, including Pyrococcus horikoshii tetrahedral shaped phTET1 (DAPPh1; FrvX; PhDAP aminopeptidase; PhTET aminopeptidase; deblocking aminopeptidase), phTET2 (DAPPh2) and phTET3 (DAPPh3), Haloarcula marismortui TET (HmTET) as well as Bacillus subtilis YsdC. All of these exhibit aminopeptidase and deblocking activities. The HmTET is a broad substrate aminopeptidase capable of degrading large peptides. PhTET2, which shares 24% identity with HmTET, is a cobalt-activated peptidase and possibly a deblocking aminopeptidase, assembled as a 12-subunit tetrahedral dodecamer, while PhTET1 can be alternatively assembled as a tetrahedral dodecamer or as an octahedral tetracosameric structure. The active site in such a self-compartmentalized complex is located on the inside such that substrate sizes are limited, indicating function as possible peptide scavengers. PhTET2 cleaves polypeptides by a nonprocessive mechanism, preferring N-terminal hydrophobic or uncharged polar amino acids. Streptococcus pneumoniae PepA (SpPepA) also forms dodecamer with tetrahedral architecture, and exhibits selective substrate specificity to acidic amino acids with the preference to glutamic acid, with the substrate binding S1 pocket containing an Arg allows electrostatic interactions with the N-terminal acidic residue in the substrate. The YsdC gene is conserved in a number of thermophiles, archaea and pathogenic bacterial species; the closest structural homolog is Thermotoga maritima FrwX (34% identity), which is annotated as either a cellulase or an endoglucanase, and is possibly involved in polysaccharide biosynthesis or degradation.	2.87928e-75

>NZ_CP019323.1|WP_076617358.1|2138734_2139589_-|PRD-domain-containing-protein
MVNILQVFNNNSVLADIGDHRQAIIKGNGIAFNKHKGSKVNTDKIEKIFYLNTKGSQENLYFLLKDIPIDIVTTTYEIIDYGNKKFDYSVLDYAYITLSDHILESTKRFNKGTYKENLIPDMEAQYPTEYAIARYALEVIQNNLGIKFPISEIRALALHFINSKGEEPEEGQLKQDESQDINDIVKKILSDNKIFRLGSNGNYFDRFMIHLQYLAGRLDKPDDGDDVLSPKFEKEMQESYPESFEIAKQIYDELQERLGNKLGSNELLYFVIHIQRLIQEDTKD
>NZ_CP019323.1|WP_076617354.1|2138350_2138704_-|PTS-lactose/cellobiose-transporter-subunit-IIA
MTVTKEDISMTGFAIVAYAGDAKSALINALNKAKEGQIDEAKKLVESANESIVDAHNEQTKLLANEAGGMDMDVTFIMVHGQDTLMTTMMLKDEVEFFIDEYERINKIEEKLDIKNN
>NZ_CP019323.1|WP_076617352.1|2136580_2138335_-|PTS-transporter-subunit-EIIC
MDVLTSKIEKMRPVFEKFAANIYVSAIRDGFIAAMPIILFSSLFLLVTYLPNAWGFYWPSNIESNLLIAYNYSMGLLALFVTATTAKNLTDAKNLDLPKTNQMNSVSIIMASEIAFIICAIVQNKGGADLTYMGTQGLIASYLVGLIVPNIYYVCIKNNVTIKMPPQVPQNISQTFKDVIPMALSVTAFWAFSLLLMSTTGKNLPELIVALLAPVFSASDSYIGLAIIAGAMAFFWFVGVQGPSIVAPAVAAIEITNTEANLKLFQAGQQATHILAQNTQDYVMNMGGTGSTFVLGFMFLLLARSKQLKAIGKASFIPVAFSVNEPILFGAPIIMNPVFFIPFILTPMVNICLYKFFIVTLGMNGMMYVMPWVIPAPIGILISTGFAPLSFVFVLLSLVIDVFIWFPFMRVYDGQMLEEEAKKAKEVGLNLDSDEENAIDDDNDSDVEVSADGTVMATASSGASATVEKVDDAASINAGFTKETAVMVICAGGGTSGILANALNKIAKDRDLPLSAAARAYGQDMNMIQDMDLVILAPQMDSMKGNVKKITDKYGAKLATTSGKEYIALTRDPDMALKFVKEHI
>NZ_CP019323.1|WP_076617349.1|2135119_2136544_-|6-phospho-beta-galactosidase
MSKTLPKDFLMGGASAAYQVEGATKEDGKGRVLWDDFLEKQGRFSPDPAADFYHRYDEDLTLAQEYGVQVIRVSIAWSRIFPDGAGKIEPRGVAYYHKLFASCEKHNIVPYVTLHHFDTPERLHEAGDWLSQEMLDDFLAYAKYCFKEFPEVTHWITINEPTSMAIQQYTSGTFPPAEKGRFDKTFQAEHNQILVHARIVNAYKDMNLGGEIGIVHALQTVYPYSDSKEDKHAAALQDAFENRLYLDGTLAGKYHQETLDLVKEILDANDQPMFKYSDSEMKEISAAAHKLDFVGVNNYFSKWLRAYDGASETVHNGTGAKGTSVSRIHGIGEEKKPDDVETTDWDWPIYPKGMHDILMRIHDEYPLVPATYVTENGIGLKEELPENATDETIIDDPKRIDYLKKYFGAIADAISDGANVKGYFIWSLQDQFSWTNGYSKRYGLFFVDFPTQKRYVKKSAFWFKKLSETHEIED
>NZ_CP019323.1|WP_076617345.1|2133967_2134822_-|PRD-domain-containing-protein
MVKIAQVFNNNSALVNLGDKRQAIVKGKGIAFGKSKGADIDTDRIEKIFYLNTKESQQNLYFLMKDIPIDVVTTTYEIIDYAKRKFNYNVLDYVYITLSDHIYGAYQRFLADTYTESVVPDMSNQYPREYLIASYGLDVINKNLNVDFPESEMKSIALHFINAKGEESKEGKLNKKQTIDINKVVKDVLGQNNIIRFDDNANYYDRFMIHLQYLAGRLDTPSKDNDKLNEKLESEMMKAYPKSFDIAKNIYEQLQLKLDKKLSGNELLYFIIHIQRLTQEKANN
>NZ_CP019323.1|WP_076617342.1|2133605_2133953_-|PTS-lactose/cellobiose-transporter-subunit-IIA
MAVTKEEISMTGFAIVAYAGDAKTALIKALNKARDGEIDEARKFLEESNQSIVDAHNEQTKLLANEAGGMDMDVTFIMVHGQDTLMTTMMLKDQVEFFIDEYDRINKIEQKLGMK
>NZ_CP019323.1|WP_076617339.1|2131828_2133568_-|PTS-transporter-subunit-EIIC
MNGIVKQIEKAQPFFKKLSANIYLQAVRDGFISLMPIIIFSSLFLLVANVPNIWGFYWPTNVSDGLLKVYNYSMGVLSLMAAANVARALTKSKNLKLAKINQIPTASVMFAAQIAFLLVAVDPFNNKLGLFFTTGYMGTKGLLAAFLVGFIVPNLYYVCFKNHITIKMPDAVPQNISSAFANIIPFALSTSVFAIFDIAFRAATGTNLAAWIIQVLAPLFTAADGYVGLAIIYGAMAFFWFIGIQGPSIVEPAVTAIYLSNVEANLKMFQTGGHATDVLAQGTQYFVATLGGTGATLVITYMFALMAKSSELKAVGRAAAIPVSFGVNEPILFGAPLILNPVFFIPFLLTPILNVWLFKFFIDHLGMNGFIYNLPWTTPGPIGLYMGTGFSIQALILVFLLLVVDFIFYYPFFKAYDAQKVAEEADKAAEAKKNGVDPNADTSAVVATAAGDIPLGLTKDKKELNILVICAGGGTSGILANALNKMSKEKDLPVEAAAAAYGAHSDLLPDMDVVVLAPQMDAMRDSLKEEADHSDVSMITTTGKQYIDLTRHADKALHFIVGKLNDKQSGDTDADPVTD
>NZ_CP019323.1|WP_076617336.1|2130593_2131586_-|dihydroxyacetone-kinase-subunit-DhaK
MKKIINNVEDIVPEMISGLVRTNSDLLKEIEGTTAVVRNDKLFSEHKQVGIVSGGGSGHEPLHAGFVGDGMLSAAVAGEVFTSPTPDQIYEAICAVDQGLGVLLIVKNYSGDIMNFDMAKEMAEADDIKIATVVVDDDISVKNSEFTQGKRGVAGTALVEKIIGAAARLGESLDELVKLGKSVVDNTKTIGIALHAATVPAVGHPGFELKDDEIEYGIGIHNERGYSVEKIQPAKELAHELIEKIIKEFDDKSGKFAVLINGMGGTPLMEQYIFANNVLDELESKNIDVEFSKVGNLVTSLDMQGISLTIMKANDDWIDKLKEPVVTIGW
>NZ_CP019323.1|WP_076618905.1|2129977_2130568_-|dihydroxyacetone-kinase-subunit-L
MKLELEQSQKWVELFVQKLETNKAYLNELDTAIGDGDHGTNMDRGAKAITESLSKKTPNTVSDLYKAVAFAMIQKVGGASGPLYGTAFLDMSKAVKTENIELSDLIQVGSDGIKRRGESDVKMKTMIDVWQPIADDLKSNKLDKANVDTALNSTKDMVATKGRASYLEEKSKGHLDPGSQSSAYLFESLVDVLGDN
>NZ_CP019323.1|WP_076617332.1|2129605_2129974_-|PTS-dependent-dihydroxyacetone-kinase-phosphotransferase-subunit-DhaM
MKFGIVIVSHSNKIAEGVKELIAEAAPNVSITTAGGTDDNEIGSSIQKVQEAVDSNTGDEILAFYDLGSSKMNLDMVSEMSDKVIHRFDVALVEGAYAAATMAQVDSPLEIIENSVKDLKIK
>NZ_CP019323.1|WP_076618908.1|2139886_2141197_-|Sapep-family-Mn(2+)-dependent-dipeptidase
MNEVRPDFQELFDEHKSEFLEYLDGLIKIPSVNGNKTFKAPFGIGPKNALDYMLNLSEKLGFRTGSVSDCVGWAEYGPENAEEYFGVLGHTDVVDVEDDWSYPPFKLTKVDNMMYGRGVLDNKGPLMSTLFALYLIKLQGIKLNKRVRIMFGTDEESGSRDIPYYLNEQKPPYAGYTPDCKFPIVYGERGLVDLTISQDISDGSIDQIESISGQFDRSYIPDYAKFKLSDGTWKEFTGKKAPSNAPDMADNVLPKIADNWVGLAGQTGDFFMWLSAKISKQTDGKNLGLDFADEESGSLQLSLYKIEKKNNKLSFNISMRYPISITEDKVLSQLKSQLKDGMSITVNRSFQSKLSEKNQEYIKQFSNIYEEDTGLDGTPVTTTGATYARALPNIVAFGPSFPGQKGIAHKGDEWLQFSDWQMMMEIYYDCFITELC
>NZ_CP019323.1|WP_076617362.1|2141220_2142333_-|M42-family-metallopeptidase
MSNEAIDLELLRNLSEADGIGGREREVSRIVHSYAQPYVDNIYYDNLGSIILKQNGINKNGPKVMLSAHMDEVGFEVRQITEQGFLKLLPIGGWWGHVMPAQEMTVTTNDNKKYIGVIGSRAPHGLSDEVKNKVMKPMSMFLDMGVDNKFEIEQMGIEIGNMITPNIKVRQMNNPNYLLGKAWDDRFSLGAELEVMKRTSVMDHEATLYFTGSTQEEVGIRGARSAVHKIKPDLAIAMDVTTAQDTPLDDRNVDNLGKGVVLAVLDSLTIANKGLLYRMKRLATEQKLDIRYDFMTVGGTDACNIHKAMDGIPTMTVSMPTRYMHSPRLMVNLDDYKQTITLLTEFCKTLSEKDVSLFKETTREALVDKY
>NZ_CP019323.1|WP_076617366.1|2142346_2143411_-|hypothetical-protein
MLSNESINLFEEISSVHGVAGNERLVSEMLRKYYEELSDDIIYDNLGSIYAVKKSKNVNAKRVMVSGHMDEIGFIINKFYDNGLIGALMLGNIPKNSLLGASVEAFNEKRHVFPGTILSIREDETVLDEKNNLIIDLGFMDKNQSETNLQIGDTISFSSEFIRTSSGTIMCRNINGRYAPVIGIELLRALDNIELPFDLYVGCTVQEQVGLRGIQTATNKVSPDLAIILESNKSFDYQLNSEDKIGILGGGLLLTYYAKTVLPNRLLISELKKLCDNNEIKYQYYYSLEDSEAGWVNKLRTGCPSLFINIPVRNFNTPKSVISEEDFGSAREALIKFIEQLDNNKIELFKSENR
>NZ_CP019323.1|WP_076618911.1|2143427_2143946_-|glycine/betaine/sarcosine/D-proline-family-reductase-selenoprotein-B
MEILIVLDQIQAGLGGTEHGDLPLGGKKIALGAADMFDKYLNKDEKITTTLFCGDEYYMKNKNEVSLKLAAMINKLKPDAVICGPAFHYVEYAEMCAQTGAIVSEKTNIPVVAAMSKECSDVIKEYSNKVDIVKMPRKGGTGLSESLQDIIDVCRKKVNGDDLNEFKEIKIY
>NZ_CP019323.1|WP_076617369.1|2143970_2145320_-|PTS-sugar-transporter-subunit-IIC
MFNKLEKVLMPAATKLGSNRILIAIRDGFLITTPLIIVASIFLLIANFPIPGWSEFWANYFGNGWESWFTNVSRAVFNTVGFFTCFSTAYAYARQIKSDAIQAAASALVAFLILTPTKMIVDGLKEPVDGVLDMEYLGTNGIFLGLIVAFIAVIIYDFVYKRGWTIKMPDGVPPAVAQSFEALIPSAFVIMVFFFIRILFGMTGFETLHNFIYQILQVPLKGAGNTLMAQIIYGFACTIFWFFGINGPAVANSVFAPITKVLTMENLDAFQNGHKLPNIFTDPFSNFFTNFGGGGSTLSLVIVMLLVCKSERIKQLGKLAIVPGFFGINEPIIFGLPIVLNPILLVPFNLVPLINLLLSTLVTKIGIIPYTNGVALPWTTPIGFSGYLSTGSLWASVYQILLLILGCLIYYPFIKTLDKQYLKEEHDAKMEKVENISFDDLTNDDLNFI
>NZ_CP019323.1|WP_076617372.1|2145346_2146063_-|GntR-family-transcriptional-regulator
MQNYLYIEIANQIKKDIDNRIYSSHQKLPSEIDLADQFSTSRLTVRKAIETLEKEQVVVKERNKGTYVLADNQKISSGSAGLSGFTEVAKKLNLKVNTKVLSFEIISNYPKEIGRGLQLKEDEMVFRIERLRLIDSNPMTLENLYLRETLLPTLNEKQASESLYNLIELSNSIGYASQELEAIQLSAEVSKKLEVEDKLPAFLAHTITYSVDGYPILYDNSYYRSDKYTFHNILYRKN
>NZ_CP019323.1|WP_076618914.1|2146101_2147055_-|N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase
MTFAMIGTWRMAYEGLSKGMELMKNGGNSSDAVETAIKEVEDYPFFKSVGYGGLPNANGLVEMDSAFMDGDTFAVGAVAGISDIKNPISVSRKLSKEHFNSFLVGSGASEYAVLNGFERKSMLTARAKKIWEKRKREIAQENLSPYDGHDTVGMISLDPKCSMAVGTSTSGLFMKKPGRTGDSALVGDGFYCDSEIGGAAATGLGEDIMKGCLCYEIVRLMGTGLTPQAACDKAVYPFIDKLKKRYGKVGEFSLVALNNKGEWGVATNVEFTFAAGDNKNAPKIMMANPGEDGTTVIEPITKKWLDAYELRIKAPID
>NZ_CP019323.1|WP_120270405.1|2147308_2148643_+|guanine-deaminase
MTYQIVFEGAIFSSVSFDKADFSPKVLTCIDQSGLIDRIISVDEPDYKSVKQTAENLNILHPIPKGSYLLPGFIDLHVHAPQWPQAGLALDKPLDEWLQKYTFPLEVKYKDLNFAKENYTGLVNELLENGTTTVLYFGSIHTDANLVLADICAEAGQRAFIGKVAMDNPTQTPEYYRDSSSKESLEQTELFINRLLDKQKKTGAELTPVITPRFVPSCTDETLAGLGNLAKKYDLPIQSHCSESIWEDHYAIERFNLRDTQVLDKFHLLTSKSIMAHATQLNDSDLELFKQRNTAIAHCPISNVYFGNSVLPVKHIHEKNINMGMGTDISGGFSPSIYRNIQQSVMSSQMLQDNSHSDSRISATNAFYLATIGGAKALHIKTGQISVGYKADFQIVTDQYFNSMSNEPQDVFERLIYHTTKSEINEVYVSGKQVINRGEHHGRK
>NZ_CP019323.1|WP_076617380.1|2148629_2149973_+|purine/pyrimidine-permease
MEENKSSLLIGPDDKVGFGEAGFLGLQHVLAMDIYVPPIILAGMMAMGIGDQMSLLQSTFLAAGIGTILQTYVFMKMPVSQGPSFVPLGAAAGVVLASGGIKGNGMATLIGSLLIGAIILIILGATGVFQKIISKLVPALVGGTIITCVGLSLIPSALNDNIFEASGNINNNIILASITALTLLISVGISMRFPKVRRIFRTGSIILALAVGTIVSSLMGLFNWKTVADAAWFSLPSGTAFNYGISFSPSAIITFIIIYAVITTETTGTWFAMGAVTNHEISKKQWNMGIIGEGFSCLVAALLGTTPVTGYSTNAGVISITGVASKRVFLFAGIWFTILGFFSKLSAFLAAIPAPVIGGVFAIICVTIMLNGLNVIRALNTTDRDIYIIGLPIILTLALVLLPASVTKQAPQILQYLLGSPIAAAAIAAIVLNLLMPKVKTLTSDAA
>NZ_CP019323.1|WP_076617385.1|2150150_2151311_-|GNAT-family-N-acetyltransferase
MTNYRLEKNDFEKFYELYLYSFNRPDNEQKKNALSDRFDHSLAYGIMNGDKLGSGLLSIPFTVNFHGVTYHMNGIGDVMSAPEFAGRGGAGTLLNQALTDMYNENVTLSYLAPFSFKYYRKFGYEQVFNHVITDIPSSKWPRIKSPNSGHIKRVRLNEVPKSARILYNNHNILGGVIREDWWWDHMAYKHSDWFAALYYNDTDELDGYLFYSNENDNLIIQEWVTNDPNSYKALANFIVKHQSMFNNFIYESPDSEVKTDLLDEPYVAKVSTIPYMSARIVNLKSFIKKYPFIKHNLDPVIIDVSDTLEWNNQTWSLSIKNGNVKFEKTSEPSSVKLDIQTLTKAMFGIRSLNSLAHYGYVQGSTVSIDTLSKILVTEKPQLRDYF

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP019323_15

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019323_15

2280955-2281066

Orphan

Consensus_repeat	Method
GAAACGTGTGACAAAACACAATTTTCCCCAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP019323_15

>merge|NZ_CP019323|15|2280955-2281066|CRISPRCasFinder
GAAACGTGTGACAAAACACAATTTTCCCCATTCAACTTAAAAAGGGTTGTGGCAACTCTGTTTTTACTCAAACTTGCGGTGGAAACGTGTGACAAAACACAATTTTCCCCAT

>NZ_CP019323|15|15|2280955-2281066|CRISPRCasFinder
GAAACGTGTGACAAAACACAATTTTCCCCAT	TCAACTTAAAAAGGGTTGTGGCAACTCTGTTTTTACTCAAACTTGCGGTG
GAAACGTGTGACAAAACACAATTTTCCCCAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019323.1\|WP_076617798.1\|2274712_2275723_-\|threonylcarbamoyl-AMP-synthase	unknown	unknown	gnl\|CDD\|223088
NZ_CP019323.1\|WP_076617833.1\|2286452_2286638_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076617810.1\|2277666_2278248_-\|thymidine-kinase	unknown	unknown	gnl\|CDD\|235272
NZ_CP019323.1\|WP_076617794.1\|2274027_2274657_-\|uracil-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234653
NZ_CP019323.1\|WP_076617843.1\|2288544_2288844_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076617791.1\|2273227_2273938_-\|F0F1-ATP-synthase-subunit-A	unknown	unknown	gnl\|CDD\|235617
NZ_CP019323.1\|WP_076617851.1\|2289145_2290582_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076617787.1\|2272990_2273203_-\|F0F1-ATP-synthase-subunit-C	unknown	unknown	gnl\|CDD\|180739
NZ_CP019323.1\|WP_076617848.1\|2288859_2289156_-\|XkdX-family-protein	unknown	unknown	gnl\|CDD\|378241
NZ_CP019323.1\|WP_076617836.1\|2287294_2288338_-\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|133475
NZ_CP019323.1\|WP_076617820.1\|2281163_2283035_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP019323.1\|WP_076617826.1\|2284849_2285527_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP019323.1\|WP_076617782.1\|2272392_2272917_-\|F0F1-ATP-synthase-subunit-B	unknown	unknown	gnl\|CDD\|180240
NZ_CP019323.1\|WP_076617802.1\|2275725_2276610_-\|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	unknown	unknown	gnl\|CDD\|236467
NZ_CP019323.1\|WP_076617813.1\|2278399_2279740_+\|Mur-ligase-family-protein	unknown	unknown	gnl\|CDD\|223840
NZ_CP019323.1\|WP_076617823.1\|2283034_2284756_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP019323.1\|WP_076617829.1\|2285527_2285737_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076617806.1\|2276554_2277652_-\|peptide-chain-release-factor-1	unknown	unknown	gnl\|CDD\|234801
NZ_CP019323.1\|WP_076617816.1\|2279847_2280831_-\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NZ_CP019323.1\|WP_076617839.1\|2288339_2288558_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377377

Protein	Function_ID	Function_description	E-value
NZ_CP019323.1\|WP_076617798.1\|2274712_2275723_-\|threonylcarbamoyl-AMP-synthase	gnl\|CDD\|223088	COG0009, SUA5, Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis].	2.98255e-85
NZ_CP019323.1\|WP_076617810.1\|2277666_2278248_-\|thymidine-kinase	gnl\|CDD\|235272	PRK04296, PRK04296, thymidine kinase; Provisional.	6.79483e-102
NZ_CP019323.1\|WP_076617794.1\|2274027_2274657_-\|uracil-phosphoribosyltransferase	gnl\|CDD\|234653	PRK00129, upp, uracil phosphoribosyltransferase; Reviewed.	4.72344e-137
NZ_CP019323.1\|WP_076617791.1\|2273227_2273938_-\|F0F1-ATP-synthase-subunit-A	gnl\|CDD\|235617	PRK05815, PRK05815, F0F1 ATP synthase subunit A; Validated.	6.794e-61
NZ_CP019323.1\|WP_076617787.1\|2272990_2273203_-\|F0F1-ATP-synthase-subunit-C	gnl\|CDD\|180739	PRK06876, PRK06876, F0F1 ATP synthase subunit C; Validated.	2.6716e-18
NZ_CP019323.1\|WP_076617848.1\|2288859_2289156_-\|XkdX-family-protein	gnl\|CDD\|378241	pfam09693, Phage_XkdX, Phage uncharacterized protein (Phage_XkdX). This entry identifies a family of small (about 50 amino acid) phage proteins, found in at least 12 different phage and prophage regions of Gram-positive bacteria. In a number of these phage, the gene for this protein is found near the holin and endolysin genes.	0.00176523
NZ_CP019323.1\|WP_076617836.1\|2287294_2288338_-\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|133475	cd06583, PGRP, Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20 kDa) extracellular proteins; intermediate PGRPs (PGRP-I) that are 40-45 kDa and are predicted to be transmembrane proteins; and long PGRPs (PGRP-L), up to 90 kDa, which may be either intracellular or transmembrane. Several structures of PGRPs are known in insects and mammals, some bound with substrates like Muramyl Tripeptide (MTP) or Tracheal Cytotoxin (TCT). The substrate binding site is conserved in PGRP-LCx, PGRP-LE, and PGRP-Ialpha proteins. This family includes Zn-dependent N-Acetylmuramoyl-L-alanine Amidase, EC:3.5.1.28. This enzyme cleaves the amide bond between N-acetylmuramoyl and L-amino acids, preferentially D-lactyl-L-Ala, in bacterial cell walls. The structure for the bacteriophage T7 lysozyme shows that two of the conserved histidines and a cysteine are zinc binding residues. Site-directed mutagenesis of T7 lysozyme indicates that two conserved residues, a Tyr and a Lys, are important for amidase activity.	1.43671e-13
NZ_CP019323.1\|WP_076617820.1\|2281163_2283035_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NZ_CP019323.1\|WP_076617826.1\|2284849_2285527_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	8.34901e-14
NZ_CP019323.1\|WP_076617782.1\|2272392_2272917_-\|F0F1-ATP-synthase-subunit-B	gnl\|CDD\|180240	PRK05759, PRK05759, F0F1 ATP synthase subunit B; Validated.	2.49731e-36
NZ_CP019323.1\|WP_076617802.1\|2275725_2276610_-\|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	gnl\|CDD\|236467	PRK09328, PRK09328, N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional.	1.1713e-101
NZ_CP019323.1\|WP_076617813.1\|2278399_2279740_+\|Mur-ligase-family-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	1.29649e-68
NZ_CP019323.1\|WP_076617823.1\|2283034_2284756_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.85551e-141
NZ_CP019323.1\|WP_076617806.1\|2276554_2277652_-\|peptide-chain-release-factor-1	gnl\|CDD\|234801	PRK00591, prfA, peptide chain release factor 1; Validated.	0
NZ_CP019323.1\|WP_076617816.1\|2279847_2280831_-\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	1.05241e-37
NZ_CP019323.1\|WP_076617839.1\|2288339_2288558_-\|hypothetical-protein	gnl\|CDD\|377377	pfam04531, Phage_holin_1, Bacteriophage holin. This family of holins is found in several staphylococcal and streptococcal bacteriophages. Holins are a diverse family of proteins that cause bacterial membrane lysis during late-protein synthesis. It is thought that the temporal precision of holin-mediated lysis may occur through the buildup of a holin oligomer which causes the lysis.	4.7467e-10

>NZ_CP019323.1|WP_076617816.1|2279847_2280831_-|serine-hydrolase
MKKFQQTEAQILDMVNQQVVPGVSYGFISNYSDSDIQTSLDESNFAGDKSWVPKITLLKGDELYDLASLTKVMGTVPIILKLIDEKKLSLHDPINKYLPQFKDGRVEIFHLLTHTSGIAGYIQNRDSLNDQQLIDALLSLPVTDNFNKKVVYTDTGMIFLGLIIEKIYQLPVQTVINNFVRDTWNLMDTTFSPEIARCTPTYEVNGQMLIGVPNDPKARQLGIHCGSAGMFSSLVDVMEFSRVMLTKKYKFLYKNFTDLFPGRSLGWDIKPGNILFHTGYTGHFIALDYIHKNAMVVLTNRVHPIEHNEVFLKHRDVILDSFLNESK
>NZ_CP019323.1|WP_076617813.1|2278399_2279740_+|Mur-ligase-family-protein
MTFKSSIATLTGKSSYFILSKFFNGGSSYPGKIAYKIDPDILTSLGKNYDLIIVTGTNGKTLTTSLINKMVTQKYDDVLTNPTGSNMIQGIVTSFVTHHKTSKKPLAVLEVDEANVEIICKYIKPKYFVLTNIFRDQMDRYGEIYTTYQKILNGIKLAPDATIIANGDAAIFSSKKLPNKVIYYGFSSKGHEKDDIKAPTNTDGVLCPNCNHIMHYHFISYANLGSYFCPNCGFKQNDLKYQVTNIKTLLPNKTEFEINGNSFTMNIGGKYNIYNALAAFAVASEMGITVDQMQKAFSYDEKVFGRQETITVDKKDVNIILVKNPVGLNQVIETILSDKSDYSLAFLLNANYADGIDTSWIWDANFEDFNYDKIPLVITGGKRVKDVTYRFKIAGLNMNKNIETVEIEDFVKQIPNIPTDKIYVLATYTAMMGLRKVLSDGGYIKK
>NZ_CP019323.1|WP_076617810.1|2277666_2278248_-|thymidine-kinase
MAQLFFKYGAMNSGKSIEILKVAHNYEEQGKSVILMTSIVDTRSGAGKIKSRMGLDRDAIALKKDSDVYDIVRRENPRAACILIDECEFMTKKQVLELTQVVDDLGIPVMAFGLKNDFKNELFEGSKYLLLYADKIEEMKTICWFCTKKATMNMRMLDGQPVYEGNQVAIGGNEMYYPVCRRHYNHPPMVENK
>NZ_CP019323.1|WP_076617806.1|2276554_2277652_-|peptide-chain-release-factor-1
MDKILEQLETLVERYAELQELMSDPEIINDTKRYMAYSKEEADMRDIVNAFNRYKELQKSISDSDEIMRETDDPEMQAMAKDELNSSKDAAEKLEHEITLLMLPKDPNDDKNIIMEIRGAAGGDEASLFAADLLSMYSKYAEKQGWTFDIVDENSTEVGGYKDVAVMITGSRVYSKLKYENGAHRVQRIPSTESAGRVHTSTATVAVMPEYDEVDIDLDPKDIRTDVYRSSGAGGQHINKTSSAVRMTHLPTGIVVAMQDQRSQQQNREKAMQILKSRVYDYYESENQSEYDEKRKSAVGTGDRSERIRTYNYPQNRVTDHRIGLSLNKLDRIMNGELDEIIDALIVNDQTQKLEQIQSGETKLF
>NZ_CP019323.1|WP_076617802.1|2275725_2276610_-|peptide-chain-release-factor-N(5)-glutamine-methyltransferase
MIKLKNWSKFKVEKLSYSNALKRAFLMLKQEKKFPEDAEYLMEELTGFNYTQLQLHRNEDVPGKIMRQFHDGVVRLGMDEPVQYILGNAYFMGRSFTVNQDVLIPRQETEEMVQKIIDDHTGKKENIWDIGTGSGVIAISLGLAFPEDDILGTDISKEALKIAELNADNYQADNVFLKQSDLFEKVIPEPFDVIVSNPPYISHQEKSVMDPSVIKYEPDLALYGDEFGLKFYQDISQNADKYLTENGILYMEFGYHQKSALEEIFAKNMPGYKVEFYKDMSGNYRYLKAEKGKI
>NZ_CP019323.1|WP_076617798.1|2274712_2275723_-|threonylcarbamoyl-AMP-synthase
METEILKNTEISKAVEFLADGKLVAFPTETVYGLGADATRPDVVKDVYAAKGRPSDNPLIVHVSSPEMVWEYADLTYKPMAEKLMSKFWPGPLTIIMPIQPGSLSKEVTGGLSTAAFRMPNNSTTLNLIKTFGKPIVGPSANTSGKPSPTLAKHVYHDLKGKISAILDDGPTKLGVESTVIDLSTDIPTVLRPGMITVEDLLQVLDNVNSDHHKVAAGEIPKAPGMKYKHYAPSAQVIIVDDTNDFTKAIAEYKTNKLGIMATEDVLSTIPDAEGQLKFSLGNDIYGASKELFAGLRGLDGQNVEYILAQGFPEADHGEAYRNRLNKSAGQKHFEK
>NZ_CP019323.1|WP_076617794.1|2274027_2274657_-|uracil-phosphoribosyltransferase
MSKFQVLNHPLIQHKLTIIRNKHTGTKVFREVANEIGELMVYEITRDLPLKEIEIETPMGKSKQKVLAGKKLAVIPILRAGLGMVDGVLELIPAAKVGHIGMYRDEKTLKPHEYFVKLPSDIDERELFIVDPMLATGGSANMAIEALKKRGAKHMRLVVLVAAPEGVKAVQEAHPDVDIYAASLDEKITDSGYIFPGLGDAGDRLFGTK
>NZ_CP019323.1|WP_076617791.1|2273227_2273938_-|F0F1-ATP-synthase-subunit-A
MNDKYKFIDFLGLRFNVANDLSALIAAILVFVLVFALSRHVTMRPGKAQNVLEWIIDFTNNIIKSLMPDAAVKQFGLYAFVLFTFVFFANQLGLIFQVKVGGYTYIKSPTTNPMVTMALALISLLISHYYSVKKFGFGGYVKNYVKPVGFLLPINILEEFTNFLTLSLRLYGNIFAGEVLLALIGTVAQSFGVVSFVVALPLEMIWQGFSVFIGAIQAYVFTTLSMVYISRKLEKE
>NZ_CP019323.1|WP_076617787.1|2272990_2273203_-|F0F1-ATP-synthase-subunit-C
MKEIAAAIAASFAALGASIGNGLVISKTLDSMARQPEISGDLRATMFIGVGLIEAVPIIAIAIAFVILFV
>NZ_CP019323.1|WP_076617782.1|2272392_2272917_-|F0F1-ATP-synthase-subunit-B
MLANLLVLGAGKLALGDMLFILISFVLLTAAVKKFAWGPVTKMMDARSDKISGDLDYADQERARADKLAKEREEALKNSRAEAIEIVNKAKDNGEDQKKSIMADAHSEAESVRQKAKSDALRAKEEAMNDAQNDIATLSMEVASKVISKELNANDQKSLIDSYIKELTVNNETK
>NZ_CP019323.1|WP_076617820.1|2281163_2283035_-|ABC-transporter-ATP-binding-protein
MAKEDTKSQPSGGHGPGHGPGLVVKPKNFWKTTGRLAKYMSTYVVGIVIVLALAIASAIFQIRTPKILGEATTEIYKGVMTGAAQQKAGIQVSQLPINFTKIEHIILIVMLMYLASALFTFLQQFTMTRISQKTVFMLRRDLKAKMERLPIGYYDSHSNGDIMSRAINDMDNIAGTLQQSVTQVVTSTVTFIGVLWMMFTISWKLTLIALATIPVSLLVVGVIAPQSQKFFKRQQKSLGLLNNQVEENYSGHVVVKSFNHESDSIEVFESENDKLYKASWKAQMISGIVMPLMTFLNNLGYVFVAMYGGISVANGNLPLGDIQAFLQYMNQFSQPISQLANLTNTIQATIASAERIFEIIDEPEMNNEKVDVPDIETEDKVTLDHVEFGYEGKPILLKDYNLHVKPGEMVAIVGPTGAGKTTIINLLERFYDVSGGSVKIDGKDVRNMTREEVRKHYAMVLQDTWLFTGSIYDNLKYSNEDATKEDIIAAAKAAHVDNFVRQLPDGYDTVLNEEASNISQGQRQLITIARAFVANPEILILDEATSSVDTRTEVHIQHAMERLLKNRTSFVVAHRLSTIRDADSIIVMNHGSIIETGNHDELMAKNGFYADLYNSQFAGNVAM
>NZ_CP019323.1|WP_076617823.1|2283034_2284756_-|ABC-transporter-ATP-binding-protein
MFKIARGRINLWQVLGAVVFMTIQVITTLYLPNITSDIVNNGVSTGDTNYIIHAGTKMILISIVSVIAAVGNVLMAAQASQGLGKKLRSDLFKKILFFTNDEFDNFDTSSLTTRTTNDVIQIQNVMIMMLRMMIMAPIMLIGASVMAYQKNSEMTKIFLISIPILIVLVGLVMFFAVPLFKAMQKKTDRLNLIFREGLTGVRVIRAFRQDGFEQGRFEEANADYTNNAIKVFTIVALMFPIVTLIMSGTNVGITWLGAKYIANQSMEVGNLIAFMTYAMQILMSFMILSLVFVFVPRASASAARIQEVFATESTIDTVAKPAKVKDAPSLSFSDVNFRYTGAENLALSNLNFKVTAGQTLAIIGGTGSGKSTLINMIPRFFDSETGVVSLNGTDVKALNTEDINKRVAMVPQKAILFKGTIRTNMTYGKDDATDDQIWHALEVAQAADFVKELDGQLDAIVEQGGDNFSGGQKQRLAIARALVKDASIYVFDDSFSALDFKTDLNLRTALKNDSAISKCVVVIVGQRISTVADADQIVVLDDGKMVGLGTHEELKENNKTYQEIIESQIKEAK
>NZ_CP019323.1|WP_076617826.1|2284849_2285527_+|CPBP-family-intramembrane-metalloprotease
MNNKINTLNPIRGLLRIIAFILLFIAEQIPLSILTLTKKDLGPKYSVYLKVAPFVTLILLAIASFIIWLVFKRAQKFKSIKFNKSTWIIIIIATILVFAVNIITVPLMKTTNDNVAALELVGKNNMLILVFFTIIVAPILEEIIFRGIFMNWFFANNPLVSVLLSGIVFGYVHAPFSPNIDWIYALSKILLGIILAAVYYRTKNIKASITVHFLNNFLAIISGLI
>NZ_CP019323.1|WP_076617829.1|2285527_2285737_+|hypothetical-protein
MKEHDKRKLNEAYQDVLRKIVIWGVLSMLLLASSKITGWIIMEFAGLISVVYTIILVGILFYIAFIKRR
>NZ_CP019323.1|WP_076617833.1|2286452_2286638_+|hypothetical-protein
MTEKLTEARIKANKKWDEDNKERKQYLNTRSVARNFIKKRATLDDINELKELIKIREEELK
>NZ_CP019323.1|WP_076617836.1|2287294_2288338_-|N-acetylmuramoyl-L-alanine-amidase
MKNKINILGLLVILAGFFLAPVTVDADVNSDFNINQNYALGAYQGDSRQAYRNYIILHESGNQNDVNDTNAVLHEVQFMHNNYSNAYATYFVGGGGQVYQVGQPGYVAWGALSANPYSPVQIELARTADRNTFNADYHTYVNLARYWANYYGIPLTLDGYGNGIKSHLWVTNNYGGDHQDPYGYLASWGITKQRLAEDLLHGFYSTPTATVIRDAVTIKDGPTTGIAGWNSKGKIIPGSNTKLRNDTAWKTSYLTTVNGLPMYRIATDEYIPKKYTSEANLVTINAISGVNAVDSTGKQISDSRKTFTDQSKWKTNDRPHWINGKLYLQVATNQYIDTYYTIGGGNR
>NZ_CP019323.1|WP_076617839.1|2288339_2288558_-|hypothetical-protein
MKTNKLSIDWHSKVWWVSLISILLVLVQQVLALFNIQLPAELSGQVMDIVNSLLAVGGLVGIIYDTSKPKEG
>NZ_CP019323.1|WP_076617843.1|2288544_2288844_-|hypothetical-protein
MPPHTFTVLGFTISDWVGIATITSLIIAAVRRILFQPLNDKLSDLSKAITELNANSNKAHSDLKDKIEENHLDIERHDIEIGFLYDKNNLNRRKKNEDK
>NZ_CP019323.1|WP_076617848.1|2288859_2289156_-|XkdX-family-protein
MLNNLITIENIRNWYESKNWTDEMVEKAIELGFITDDDFTKIKANIEAKKQSILDAQKAEEDRIEAEKQAEIDRQAELEKSMTDEPVEDNTEDTDTTG
>NZ_CP019323.1|WP_076617851.1|2289145_2290582_-|hypothetical-protein
MISEVKLDINKAGQFINRPVTLRSGDTDNTIKATIYQNGTPYSNFKTATFSGNRSDGTAIANDPATISGNVITYNVAPAVTSKNTKIRNAYFLLNGNISTESFEVVVIPGTIIDGDLKSYVPGVSDDLISQFENVTKQSDAYLQELKSNVKTGTNSINGLNSKLAGITSSVNALQGKVNIGGVNLLANGDFSNSLMNWNIYNAENGTVAVENDEAGNKMLHIHSSNGPTGIFTSSPSYYGSNSLKSGESWIASGLVKGDATIIRFGIETGKYPENPYKNPTDSWSKIVSKNIRAASNRFCIYISSGDLYVKFVKVERGNIETDWTPALKDEVNTSDTADWQKSKITKDDGSSSISLSDNSTTVDVTFKSLISGLKTFYIQGDKAGNTLGDSIRGQIYKSDVNNGYAFGVTNGGKMYFKYITSGVVGSWQQVATVASAAPVAAMAYTAMVQDDTNKTLQAQNSQIAYSLMTQGGATDAK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP019323_16

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019323_16

2347913-2348002

TypeV

Consensus_repeat	Method
AAAACATGTGCCAAAACACAATT	CRISPRCasFinder

1 spacers

cas14j

The CRISPR arrays of NZ_CP019323_16

>merge|NZ_CP019323|16|2347913-2348002|CRISPRCasFinder
AAAACATGTGCCAAAACACAATTCAATATAATTCAAGAGGTGTCTTGATATAACTTGTTTTCTTACGAAAACGTGTGCCAAAACACAATT

>NZ_CP019323|16|16|2347913-2348002|CRISPRCasFinder
AAAACATGTGCCAAAACACAATT	CAATATAATTCAAGAGGTGTCTTGATATAACTTGTTTTCTTACG
AAAACGTGTGCCAAAACACAATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019323.1\|WP_076618082.1\|2343861_2345853_-\|polyphosphate-kinase-1	unknown	unknown	gnl\|CDD\|235469
NZ_CP019323.1\|WP_157886454.1\|2357392_2358223_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|283645
NZ_CP019323.1\|WP_192844214.1\|2351822_2353076_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|224136
NZ_CP019323.1\|WP_076618961.1\|2349751_2351776_-\|cellulose-biosynthesis-cyclic-di-GMP-binding-regulatory-protein-BcsB	unknown	unknown	gnl\|CDD\|377001
NZ_CP019323.1\|WP_076618060.1\|2339513_2339759_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NZ_CP019323.1\|WP_076618100.1\|2348907_2349762_-\|GGDEF-domain-containing-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076618068.1\|2340759_2341929_-\|transposase	cas14j	-	gnl\|CDD\|223747
NZ_CP019323.1\|WP_076618065.1\|2339966_2340677_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|315383
NZ_CP019323.1\|WP_076618057.1\|2339291_2339480_-\|CsbD-family-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076618054.1\|2338509_2339226_+\|Ltp-family-lipoprotein	unknown	unknown	gnl\|CDD\|377866
NZ_CP019323.1\|WP_076618073.1\|2342102_2343038_-\|NADP-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|176191
NZ_CP019323.1\|WP_192844192.1\|2354630_2356124_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076618112.1\|2356135_2357260_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076618117.1\|2358544_2358919_-\|DUF1801-domain-containing-protein	unknown	unknown	gnl\|CDD\|227933
NZ_CP019323.1\|WP_076618051.1\|2337605_2338328_+\|SHOCT-domain-containing-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076618078.1\|2343290_2343776_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
NZ_CP019323.1\|WP_076618086.1\|2345842_2347219_-\|DUF2252-domain-containing-protein	unknown	unknown	gnl\|CDD\|313268
NZ_CP019323.1\|WP_076618108.1\|2353081_2354644_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227617
NZ_CP019323.1\|WP_076618120.1\|2358974_2360723_-\|YfhO-family-protein	unknown	unknown	gnl\|CDD\|227904
NZ_CP019323.1\|WP_076618095.1\|2348096_2348876_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP019323.1\|WP_076618082.1\|2343861_2345853_-\|polyphosphate-kinase-1	gnl\|CDD\|235469	PRK05443, PRK05443, polyphosphate kinase; Provisional.	1.48129e-172
NZ_CP019323.1\|WP_157886454.1\|2357392_2358223_-\|alpha/beta-hydrolase	gnl\|CDD\|283645	pfam06028, DUF915, Alpha/beta hydrolase of unknown function (DUF915). This family consists of several bacterial proteins of unknown function. Members of this family have an alpha/beta hydrolase fold.	2.30491e-69
NZ_CP019323.1\|WP_192844214.1\|2351822_2353076_-\|glycosyltransferase	gnl\|CDD\|224136	COG1215, COG1215, Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane].	2.00993e-64
NZ_CP019323.1\|WP_076618961.1\|2349751_2351776_-\|cellulose-biosynthesis-cyclic-di-GMP-binding-regulatory-protein-BcsB	gnl\|CDD\|377001	pfam03170, BcsB, Bacterial cellulose synthase subunit. This family includes bacterial proteins involved in cellulose synthesis. Cellulose synthesis has been identified in several bacteria. In Agrobacterium tumefaciens, for instance, cellulose has a pathogenic role: it allows the bacteria to bind tightly to their host plant cells. While several enzymatic steps are involved in cellulose synthesis, potentially the only step unique to this pathway is that catalyzed by cellulose synthase. This enzyme is a multi subunit complex. This family encodes a subunit that is thought to bind the positive effector cyclic di-GMP. This subunit is found in several different bacterial cellulose synthase enzymes. The first recognized sequence for this subunit is BcsB. In the AcsII cellulose synthase, this subunit and the subunit corresponding to BcsA are found in the same protein. Indeed, this alignment only includes the C-terminal half of the AcsAII synthase, which corresponds to BcsB.	4.01573e-18
NZ_CP019323.1\|WP_076618060.1\|2339513_2339759_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	5.56626e-11
NZ_CP019323.1\|WP_076618068.1\|2340759_2341929_-\|transposase	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.2102e-43
NZ_CP019323.1\|WP_076618120.1\|2358974_2360723_-\|YfhO-family-protein	gnl\|CDD\|227904	COG5617, COG5617, Predicted integral membrane protein [Function unknown].	7.12145e-11
NZ_CP019323.1\|WP_076618065.1\|2339966_2340677_+\|alpha/beta-hydrolase	gnl\|CDD\|315383	pfam12695, Abhydrolase_5, Alpha/beta hydrolase family. This family contains a diverse range of alpha/beta hydrolase enzymes.	9.09135e-70
NZ_CP019323.1\|WP_076618054.1\|2338509_2339226_+\|Ltp-family-lipoprotein	gnl\|CDD\|377866	pfam07553, Lipoprotein_Ltp, Host cell surface-exposed lipoprotein. This is a family of lipoproteins that is involved in superinfection exclusion. Proteins in this family have been shown to act at the stage of DNA release from the phage head into the cell.	3.33442e-21
NZ_CP019323.1\|WP_076618073.1\|2342102_2343038_-\|NADP-dependent-oxidoreductase	gnl\|CDD\|176191	cd05289, MDR_like_2, alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases. Members identified as zinc-dependent alcohol dehydrogenases and quinone oxidoreductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	4.55019e-95
NZ_CP019323.1\|WP_076618117.1\|2358544_2358919_-\|DUF1801-domain-containing-protein	gnl\|CDD\|227933	COG5646, COG5646, Uncharacterized conserved protein [Function unknown].	2.13929e-34
NZ_CP019323.1\|WP_076618078.1\|2343290_2343776_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	4.31831e-12
NZ_CP019323.1\|WP_076618108.1\|2353081_2354644_-\|hypothetical-protein	gnl\|CDD\|227617	COG5298, COG5298, Uncharacterized protein conserved in bacteria [Function unknown].	1.88771e-12
NZ_CP019323.1\|WP_076618086.1\|2345842_2347219_-\|DUF2252-domain-containing-protein	gnl\|CDD\|313268	pfam10009, DUF2252, Uncharacterized protein conserved in bacteria (DUF2252). This domain, found in various hypothetical bacterial proteins, has no known function.	3.39139e-116

>NZ_CP019323.1|WP_076618086.1|2345842_2347219_-|DUF2252-domain-containing-protein
MTNPTPYTFQDTDAFKSTEQLIIKGRYFATMVPEDFDQFVPEKRNIHKILNIKNKLLVPELIEVKRERMSKSLFAYFRGTADVMHYDLSNRPDSGIKVLIGGDAHLGNFGFYGSSEGQLLFDMNDFDEAHLSYWEYDLKRFLISALLVARSHSFEETDIQEFLLKTVHTYFDTLKHMTKISEMKRFILPNTLQNITEIFGDLKDNEEYFQQSFEKLITKSIKKAQKSNSKLVIEKYTTVNELGERKFVENKPVTQHISKEDFKALIDGYSKYKKKQRSDVRLFLEDFNVIDVVRHSVGVGSVGTLCYLILLRDLDKNYLVLQAKQALPIYNNDELYTDKNNSQGQNIVDSQLILQSASDPFLGAFDTKKYSFYMRQFKDMKTSINLDKLDFESFEDYVTVCCILLARAHSHSPNYPLIIGFGEEFKDLDNSLMNFVNSYTKQVMFDYDSFKEDVANEG
>NZ_CP019323.1|WP_076618082.1|2343861_2345853_-|polyphosphate-kinase-1
MKDKYYNRDLSWILFDNRVIDQAFNKKIPLLEKLRFLSIASNNLDEFFGVRLHNVQTMISKNRVDKRTGLNGTELLAQIYEFNSRNITKEYQALGLVLEELKEKNIFEVTRYYKLSSMEKAQVDDYYDKVISNEIKVEEFSPENKTKADLNFLLVSDDKNYTIQVPEDLDRLVDTGVPDKYILLEDLIFNNLEEIIQKFKITKQFVYRVTYDKNKKYDFLDKGLSDEKYLSEMTNYINDRGPGKITRVEFYSPEHKGRSFLSGLFGISKKSIYAIPGPVNLKVLDKLFKKYKNNQKLVFPAFEGLTWKKSKNILRHLDNKSLLVQYPYDSFEIFLNFLNTAVDDPKTTNIQMTIYRTEKNSQVVKLLQRAASKGISVKVVVELRARFDEAHNLEVAKELKDSGCRVLYGDKVNKVHAKICLVLQNDRGYVQIGTGNYNAITSKVFSDISFYTSNKRYVGDAVKFFDGLSGEISNGYELMTASPDNLKRMILNKIKKATQDYLRNGKGSVFMKVNGLTDIDIINGIYRAARLGLPFSIIVRGPCSLRLGICGQKENIVVKSIVGELLEHSRIYKFNYSDGTNEVWISSADTMTRNLDRRVELAVPIVESKPKRKINKLIEMYCKDTTNSYYLNNDGEYFKCQNKFYNFSAQQNWLRKIKYRKYV
>NZ_CP019323.1|WP_076618078.1|2343290_2343776_-|GNAT-family-N-acetyltransferase
MKYRFAKIEDLEDIMKIEHASFNVDEAGSESVYDDRISKLTDTFLLAQNDDDKIVGFIVGPAVKDRYITDKMFKKSPRNLMLGGHQLVFSIAIDPDFRGQGIGSELLKKFEENAQKAHRETISLTCLADRIPFYEKNGYIDKGISESKHGNETWHNMEKSL
>NZ_CP019323.1|WP_076618073.1|2342102_2343038_-|NADP-dependent-oxidoreductase
MQTNAIVIDKYGDSGEFSEKIVDIPELKPKQLLIKVSSSSVTPFDIGVRKGNFKDDFSLSMPAITGTDVAGEVVDKGNEVNKFEIGDIVCGMVGVKGFGAYSDYAILGQSKAVKVPKDVDVKYAGILPMIATPAYNALFDLGKLVSGEKILIHGGAGGVGSMAIQLAKNAGATVYTTASKRNFEDLKNLGASEVLDYHNDKFNKVLSDMDAVIDTVGHDTYKDSFEVLKSGGRLVSLVEEPNEELAKRFNVSAMYLGGKFDNPLGKVIGLVSEGKIKLNIQKSFPLTADGVRDAQDYYETNHVFGKVSLAK
>NZ_CP019323.1|WP_076618068.1|2340759_2341929_-|transposase
MVLKGLKLRIYPDTYQQEMIDFNFGANRFIWNQMLDMLIKRYENNKDSKFLNAFDLNNLLRQLKIEYPWLRRAESTSLQSTDHDLVEAYKRFFKKSHNFPKFKSKKYPKQSYQSKCVNKNIKMIDKTYIQLPKLGAMKFKSGKHVPKIIKSVTIRKSFTGKYYAVLLVECENQTFEKTKCTVGIDLGVADLAITSDGKKYPTIRFDKLLAGKKHYWEKRLTRRWLGAIQHIQYEKKFGLIDPKPLEQYSNYMKAKIMVAKYNEKIANQRIDYLHKLTTQLVKDYDVIVIEDLKTSNLIKNHKLARAIANQSWRELRSMLEYKCSWYGKELVVVNPYKTSQRCSNCAYDDGKHTLDVREWTCPNCHTNLDRDINASKNIKKLGLEQTLVN
>NZ_CP019323.1|WP_076618065.1|2339966_2340677_+|alpha/beta-hydrolase
MKKIFKWIIGILIILIIIIGATFAVVKHMEYQPTSAALKASETTTSVSNTIKFQGDDTKPVVIFYPGALVDPLSYSIWANKLARAGYTVYIVRFPLDLAVINANAAKEVQNGGPYIICGHSLGGTMAARYAHKNTKELKGVFLLGSYPEKKGNLRNVKEPVISITASRDGVLNQKAYKKSKKYLPKNTDFVTINGGNHAGFGSYGKQSGDNSAKISNSDQQKIVADLLLRWLDKIK
>NZ_CP019323.1|WP_076618060.1|2339513_2339759_-|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MHWLWVLIVGAIIGTVAGAITNRGQSMGWIANIFAGIVGSFIGEGVLGSCGPQLAGMAIIPSLIGAIILVLLVSFVMGKRS
>NZ_CP019323.1|WP_076618057.1|2339291_2339480_-|CsbD-family-protein
MSIDSKEDMIKGKTNQAVGKVTNDDKKELKGKIQEKVAQAKEKGEDVIDKVAKKVNKKNDSK
>NZ_CP019323.1|WP_076618054.1|2338509_2339226_+|Ltp-family-lipoprotein
MATRKHGKAKKPIYKRVWFWIIIVLVIAIFIPGGGSDYEKTAKTDNTKTTAVKKSDSDNKSTSSKPVSKPVAKKSDNESTSSQESNVPADYASALNSAKTYSSSMNMSKQGIYNQLTSDAGEQFSAEAGQYAIDNLSADYNENALKTAKTYSSDMNMSKQGIYEQLTSTNGEQFTAEEAQYAVDNLKADYNENALKSAKSYQDDMDMSPDAIKDQLSSSSGEQFTPEEADYAIQHLND
>NZ_CP019323.1|WP_076618051.1|2337605_2338328_+|SHOCT-domain-containing-protein
MGIWDSIKRGASNMSRLSELESKLRNNQNLTNSELAEFEQLSKSTLNEIFEKKPGKFFKGTSNYGQISIDENKQLFKLNTKVYHFENLNTYELLENESSISSGGLGIGRAIVGGALVGSVGAVIGGTTKRRKNTNIVESLKIFISFKGIREISTTLPFITKKQKKDKKYEKQLVSAKETLAGLDYISNFMNNQIQSNQQVNTTQSNSADEIRQYMELLNDGIITPQEFEYKKNEILNRRI
>NZ_CP019323.1|WP_076618095.1|2348096_2348876_-|hypothetical-protein
MSDYLKWILEIIVAFTLVPYLTARLVSWFGHVAKSVLVNNLGNNSQLVVGGLGVIIHELGHAIFAFIFGHNVKKVQLLNFNYRNSGSLGSVEHTWNEKNIYQRLGNFFIGLAPYYMCSIVLYLLQKIMLNARLSFSGLGSNTDITLSGITELVLNNLKTSYTNGTWSMILLYLVLTIMIASTGYDLSDADFQTVNKGILPWVVVQFVIGNVFILLGKMDTLNNYLLEFTSFSILFMVHAALSMLLAIVVIKIIGMFNIF
>NZ_CP019323.1|WP_076618100.1|2348907_2349762_-|GGDEF-domain-containing-protein
MGNKDQRTSLLADVGLLMFLVLFSATAILMSLSGQVLLNVIYLFGTVALLMLTYFFGIMPSLIANILFIAMQATIMVYQYVAKGSTIHWQLAFWMVIPILLCLTLYCMTYNQLKLQDANAELRTAMVEQGAFDEQTHLRTTVAYMEDTAVYAETNKRFQLPVTTAVIKIGYYNDIRRMMSEHQVQSLLQMTTDAIKDKTRINDIIYLVNNDDPTWAILLFSNADGTTIATNRVKEGFDERLKNNPDLSTMAISLVVGIASWDGEKMKTPYDLLNAAVRETQYDV
>NZ_CP019323.1|WP_076618961.1|2349751_2351776_-|cellulose-biosynthesis-cyclic-di-GMP-binding-regulatory-protein-BcsB
MVTTTNVSAADMQTYTQQFQNSTTTLSGRSVESNMYLTKMDYWDVKKVTFNFNFQVSQLATRDMSDITVSLNGVKFYSFRPSKKTGTQSKTITVPVKLLGGSNKLQIEGQILSSDNNDNYQLAQTPANWLTIEKGSNVNFEYDLKDADDTIDSFYDHFSGQDTISYARSRIATANDPTPYELTASMIALAGESRVITTVNDQIPVVKMDKINSSDGDYVMVIAKYNHLASEFKKQISSEEINGRGVIKTYYNGGKRYLIVTANTGSLLKKAARFVANAELMKESTQSTEYITDSTATFTSSLHDNGVKTLTSSIDTITGAGHRESDYLVSLPNDRTNADGSEVYLKFRYSKNLNFHRSLVTIKINGTTLGSKKLSSVRADNDTLTVKVPRGLDLGNSFTVSVGFDLEMEDQNSSDNSQTPWAEVDTQSKMYVKSKRSNDLLFSNYPTLFINNQTYDNIAVVAPNKLSDDDFKTLTNVFNLIGNFSKSNTGNIQFYSKMPSKNVLKNKNVIVIGTPKNNAMIKSLNSKLYFKYSKNFSRIISNEKLSIEHNYGKTIGTAQLLRSPYNDKRGMLVVTGANDNAVYLASTQINFQANIQQYSGDGIVVDTNNTHYGYRFKKNKAIDKSLTTKQLISNNTQLIIYLVLALVAIIIIGAAVFLVMRKQGLMSGGHKHGK
>NZ_CP019323.1|WP_192844214.1|2351822_2353076_-|glycosyltransferase
MSILDIFLFIAVIAIWGTLVVNLILTIAGYTWYLRNVNKPAPKLPKKAPFVSILVPAHNEGVVIVKTVLSLLSFDYPQDRYEIIIINDNSDDNSAQLLANLQDKFPHERLKVINTDKTNGGKGKSNALNIGLKQAKGSIISIYDADNTPEHQALRVLVAELLQDDKAAAVIGKFRTRNKMATLLTRFINIETLSFQWMAQAGRQQLFNLCTIPGTNYVIRRSVIEKVGGWDVKALAEDTEISFRVYEMGYRIRFQPKAVTWEQEPQTLDVWFHQRTRWVKGNIYVVVKNAHLLFKKEGRRIRFDLLYFLSIYFLLMTSLILSDSVFILSVAGLAHSDLQGFSNSLWLFAVLMFVISTFVTITTERGELTFSNLLLIVFMYLVYSQMWLAVAAYGMVGYIREQVFHKQAKWYKTKRYQ
>NZ_CP019323.1|WP_076618108.1|2353081_2354644_-|hypothetical-protein
MRLNKLSKLVSLLCLPLLFYVFSTQLVKAEAATSNKVMLVYDSKNTTDQYDVKVDALQRSLTSMNLQVKTLSQNDYKSGMLTKKYVGVITMINWKQVGLTNKTFIKDRSKFSGIKLHIGDELTSEEKTQLGAKSTRLYQQQLILKNKNTSQVLPFSETIDVLQDLPSGSQQIGTLSTQQENAKIYGYGVINGNYGFLPYFDSKGLSLITATEMIAKLFNRAGSYQPLLTITDVTPVSDLKILDQLSKFCYENSIPFAISTTTVSKNTEMKAFSKFTAVLRNIENRGGVIFIRSPEIGGPGVDSGNDLRQRLTSYVVSLAKGQVYPIGISSEGFWNQDKVLRQNFLIKADHWILLPNKQVVYVSEDDDAKAAKQSFFAISASSLNSVKKTEETRFSTPSAVTIPMPNSSKGLVDFEKQVNKLKFSWFDPMSTSMSTSITTGTSTVSFKDSNYFVNGKQEEIGTADSSKIFNETIKTKPVLSNYFNIQGNVLTILFIIVAIILIVFILIGRRIYWNRFNKRK
>NZ_CP019323.1|WP_192844192.1|2354630_2356124_-|hypothetical-protein
MKIITKKLLVKFSDYISPALLATILAAIISGVLLFVSPIHGYADNGDFYRAMLTNSIYRLPYDHTSTIDYVVTKFGIYQYFNENGMIAFSSQTIFIQIALFFNKIFYSTKFFDIRFLGAVYYVFYLGAIYLLTKSFVYPYKRVRSYMVALLVVLVFADSSFTLYFNSFFAEPVMYIFMLYGFAAIMLLAKGSYKRNWPMITLFFVSIILLITDKSQNAPLALSFSAVSIGMMFLPHFRARRFAIMLGMFVLMGTGVFTYTAIKKEFNDVNQYQSFTHGVLMDTGDPSKKIEKQGMDEQFALLREEDYYPKTYTVIKVDNGVIQKKLLPNNGIGWTLKYYAHNPKQFGVLMDLASQDIMITQVKAVGDYIPSSHKPSKQLRYFTTYSQFMGAFFPGKFAFIIMLLIGLISCYSVGLYMDLREKRPHGVVRFFLVFGLCTIVFFVPIIAIVGDGDADLAKHIFMTPLSLDLMFVLFISDVLHHRLWDTSPREEFLDEAK
>NZ_CP019323.1|WP_076618112.1|2356135_2357260_-|hypothetical-protein
MKKILILLMILPTIVLAGCSKKSDVKVSEPDMSTSNFLNSSNYGDYSTQNKLLYKFVTNKMLTKEGIYTNYKETKNQSNVATGHEMLSESSGLWLEYLVYTKQYKKFREFYKQTKNTFDQGDQFSYRYDPNTKKKSNVNATLDDLRIIRSLQMYAQATKSSKYKKEAATRFAKLKSGSIPNGKLVDFYDTKAKKSSSTGSLAYYDFKTLKYFESTSSKEKKYYKKQLKVVQNGYLGDAFPLYSSSYDWGQGSYSSKDLNTSEALETVLHLSEVGKVKKVTLNWLERQVKQRKLYNTYTINGSVVDKDQSTGSYALAAMIFANAKNEKMYKYTMKIMWSSQVTDDSSPIYGALGVKHLKQAYSFNNLYGLIASKY
>NZ_CP019323.1|WP_157886454.1|2357392_2358223_-|alpha/beta-hydrolase
MKKLKVFIAIIAFLAIFNVSKPTNVQAASSDYIPTIYLHGHGAGARSTDDMINFAQTHFHATRALLVVVDRQGVPHFFGTMDKSTYRPIVQVVFKDNMNTNFNVTSGWLHEIMTQLKQNYGVTKFNAVAHSMGNMTLLYYMLNYGKDKNLPQLNKQVDIAGHYDGIAGIKDKPNSNWFMKSGRPAYITYDYQHALKLRKNYPYKQVKILNFYGNLSNGTNTDGRVSTVSARSIKYILRGRYKSYRQVKITGYMGEHSMLHENPKVDRIMGDFLWNK
>NZ_CP019323.1|WP_076618117.1|2358544_2358919_-|DUF1801-domain-containing-protein
MDEFEDFLLNIEDESHRKRMADIINWVSFTFPNLKKRFAWKQPMFTDHGTFIIGFSVANKHISVAPEEKWMNLFVSKAEGSGYTHGTRMFRIGFDQEVDYDLLKEIIEFNIEDKKDCDTFWRKK
>NZ_CP019323.1|WP_076618120.1|2358974_2360723_-|YfhO-family-protein
MKKLVKEKYLILLLFLFISIALIGIIDWHYGYVFATGDFHYHLDRIETLASSIKHLNFWPKVDGHFIGGYGYASSLFYPDLFLYPAALLRVIGATPVFSYLFTLVMINFVTLWIGFIAGKRMSLSPNKALLFTLIYTFNAYRLQTLFSRQDLGELMGAMFFPLVLSELINLKRGNVKQWYVLAFAMIGISCSHTISLFMIIVFASLFVLLNIRIFWNKKRILAIVKAAGLTIGISAAVYLPILEQMQGQKYALTTDPLIKVTNEILPMKNLILNSLTNQVFHANTVNLGAIIFLGLAVYAIYNLIHRRNLDLTLIALVFFIACTNLFPWGIFSHSIFAMIQFPWRFFSVISLIVAYLLANDDLNLFRNQYVIYGFVALLSIVTAGLSQQTLAESPDKLESYQQFNKVDSFFIGAGHEYLPSEVSYPEVLDHKDRLIKYNKSNVKISNSTINRQYIAFNFNTHGKTSKVQLPLIYYKGYQSEVYGNTGSSTTPRISSNGLTTIELVGSGTVKVQYENTFIQKFSLMVSASVLLLTLLMLLKKRRDNTSLSDSVPLLIEPVNNDYVFVYKIINGYTEPMKKNLP

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP019323_17

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019323_17

2382614-2382729

Orphan

Consensus_repeat	Method
CGATACAAAACATAATTTCTTCCGCTTAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP019323_17

>merge|NZ_CP019323|17|2382614-2382729|CRISPRCasFinder
CGATACAAAACATAATTTCTTCCGCTTAACTTTTCCAGTCAAAAGAATGTGTGCTTTTCTTTTTTATCCTCAAACTTGCTGAAACGCGATACAAAACACAATTTCTTCCGCTTAAC

>NZ_CP019323|17|17|2382614-2382729|CRISPRCasFinder
CGATACAAAACATAATTTCTTCCGCTTAAC	TTTTCCAGTCAAAAGAATGTGTGCTTTTCTTTTTTATCCTCAAACTTGCTGAAACG
CGATACAAAACACAATTTCTTCCGCTTAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019323.1\|WP_076618198.1\|2376546_2377524_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226605
NZ_CP019323.1\|WP_125673064.1\|2382814_2385001_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|173886
NZ_CP019323.1\|WP_157886456.1\|2387500_2387653_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076618187.1\|2374889_2375069_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076618974.1\|2387880_2388711_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381359
NZ_CP019323.1\|WP_076618227.1\|2391474_2392047_+\|flavodoxin	unknown	unknown	gnl\|CDD\|180850
NZ_CP019323.1\|WP_076618213.1\|2386569_2386959_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|334619
NZ_CP019323.1\|WP_076618224.1\|2390812_2391400_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP019323.1\|WP_076618175.1\|2371979_2372837_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187578
NZ_CP019323.1\|WP_076618180.1\|2372983_2374000_-\|DUF916-and-DUF3324-domain-containing-protein	unknown	unknown	gnl\|CDD\|371730
NZ_CP019323.1\|WP_076618191.1\|2375090_2375780_-\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|376808
NZ_CP019323.1\|WP_076618183.1\|2374098_2374710_-\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
NZ_CP019323.1\|WP_076618204.1\|2378914_2380714_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP019323.1\|WP_076618977.1\|2388818_2389241_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133384
NZ_CP019323.1\|WP_076618194.1\|2375846_2376623_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224026
NZ_CP019323.1\|WP_076618201.1\|2377549_2378515_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380548
NZ_CP019323.1\|WP_076618170.1\|2371368_2371815_+\|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224870
NZ_CP019323.1\|WP_076618216.1\|2387065_2387500_+\|ACT-domain-containing-protein	unknown	unknown	gnl\|CDD\|179848
NZ_CP019323.1\|WP_076618219.1\|2389309_2390638_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP019323.1\|WP_076618210.1\|2385322_2386507_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371

Protein	Function_ID	Function_description	E-value
NZ_CP019323.1\|WP_076618198.1\|2376546_2377524_-\|ABC-transporter-permease	gnl\|CDD\|226605	COG4120, COG4120, ABC-type uncharacterized transport system, permease component [General function prediction only].	4.78902e-93
NZ_CP019323.1\|WP_125673064.1\|2382814_2385001_-\|hypothetical-protein	gnl\|CDD\|173886	cd01951, lectin_L-type, legume lectins. The L-type (legume-type) lectins are a highly diverse family of carbohydrate binding proteins that generally display no enzymatic activity toward the sugars they bind. This family includes arcelin, concanavalinA, the lectin-like receptor kinases, the ERGIC-53/VIP36/EMP46 type1 transmembrane proteins, and an alpha-amylase inhibitor. L-type lectins have a dome-shaped beta-barrel carbohydrate recognition domain with a curved seven-stranded beta-sheet referred to as the "front face" and a flat six-stranded beta-sheet referred to as the "back face". This domain homodimerizes so that adjacent back sheets form a contiguous 12-stranded sheet and homotetramers occur by a back-to-back association of these homodimers. Though L-type lectins exhibit both sequence and structural similarity to one another, their carbohydrate binding specificities differ widely.	2.14747e-08
NZ_CP019323.1\|WP_076618974.1\|2387880_2388711_-\|aldo/keto-reductase	gnl\|CDD\|381359	cd19133, AKR_AKR5F1, the AKR5F family of aldo-keto reductase (AKR). Klebsiella sp. 2,5-diketo-D-gluconic acid reductase (2,5-DKG reductase) is a founding member of aldo-keto reductase family 5 member F1 (AKR5F1). It catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).	1.82059e-161
NZ_CP019323.1\|WP_076618227.1\|2391474_2392047_+\|flavodoxin	gnl\|CDD\|180850	PRK07116, PRK07116, flavodoxin; Provisional.	5.19794e-22
NZ_CP019323.1\|WP_076618213.1\|2386569_2386959_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|334619	pfam01638, HxlR, HxlR-like helix-turn-helix. HxlR, a member of this family, is a DNA-binding protein that acts as a positive regulator of the formaldehyde-inducible hxlAB operon in Bacillus subtilis.	2.17442e-43
NZ_CP019323.1\|WP_076618224.1\|2390812_2391400_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.15021e-20
NZ_CP019323.1\|WP_076618175.1\|2371979_2372837_-\|SDR-family-oxidoreductase	gnl\|CDD\|187578	cd05269, TMR_SDR_a, triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs. TMR is an atypical NADP-binding protein of the SDR family. It lacks the active site residues of the SDRs but has a glycine rich NAD(P)-binding motif that matches the extended SDRs. Proteins in this subgroup however, are more similar in length to the classical SDRs. TMR was identified as a reducer of triphenylmethane dyes, important environmental pollutants. This subgroup also includes Escherichia coli NADPH-dependent quinine oxidoreductase (QOR2), which catalyzes two-electron reduction of quinone; but is unlikely to play a major role in protecting against quinone cytotoxicity. Atypical SDRs are distinct from classical SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.93185e-73
NZ_CP019323.1\|WP_076618180.1\|2372983_2374000_-\|DUF916-and-DUF3324-domain-containing-protein	gnl\|CDD\|371730	pfam11797, DUF3324, Protein of unknown function C-terminal (DUF3324). This family consists of several hypothetical bacterial proteins of unknown function.	2.24291e-45
NZ_CP019323.1\|WP_076618191.1\|2375090_2375780_-\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|376808	pfam02525, Flavodoxin_2, Flavodoxin-like fold. This family consists of a domain with a flavodoxin-like fold. The family includes bacterial and eukaryotic NAD(P)H dehydrogenase (quinone) EC:1.6.99.2. These enzymes catalyze the NAD(P)H-dependent two-electron reductions of quinones and protect cells against damage by free radicals and reactive oxygen species. This enzyme uses a FAD co-factor. The equation for this reaction is:- NAD(P)H + acceptor <=> NAD(P)(+) + reduced acceptor. This enzyme is also involved in the bioactivation of prodrugs used in chemotherapy. The family also includes acyl carrier protein phosphodiesterase EC:3.1.4.14. This enzyme converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine residue from ACP. This family is related to pfam03358 and pfam00258.	3.039e-33
NZ_CP019323.1\|WP_076618183.1\|2374098_2374710_-\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	5.49765e-15
NZ_CP019323.1\|WP_076618204.1\|2378914_2380714_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.8984e-165
NZ_CP019323.1\|WP_076618977.1\|2388818_2389241_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133384	cd01109, HTH_YyaN, Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB. Putative helix-turn-helix (HTH) MerR-like transcription regulators of Bacillus subtilis, YyaN and YraB, and related proteins; N-terminal domain. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	5.57435e-40
NZ_CP019323.1\|WP_076618194.1\|2375846_2376623_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224026	COG1101, PhnK, ABC-type uncharacterized transport system, ATPase component [General function prediction only].	1.00437e-107
NZ_CP019323.1\|WP_076618201.1\|2377549_2378515_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|380548	cd06325, PBP1_ABC_unchar_transporter, type 1 periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally.	4.21969e-103
NZ_CP019323.1\|WP_076618170.1\|2371368_2371815_+\|Rrf2-family-transcriptional-regulator	gnl\|CDD\|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	1.13924e-24
NZ_CP019323.1\|WP_076618216.1\|2387065_2387500_+\|ACT-domain-containing-protein	gnl\|CDD\|179848	PRK04435, PRK04435, ACT domain-containing protein.	2.1146e-61
NZ_CP019323.1\|WP_076618219.1\|2389309_2390638_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.64134e-51
NZ_CP019323.1\|WP_076618210.1\|2385322_2386507_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.07577e-94

>NZ_CP019323.1|WP_076618204.1|2378914_2380714_-|ABC-transporter-ATP-binding-protein
MAENKRQSIWARSMPVKEQLTVIKRLISYAKPFKWYFIITIILSGTISLVNIYLPKILQIFIDKYLRVGKADINIMWFFAGLYLFGMLTRAVMQFFQNYTSTMGAEYMLESVRREMFTKLHKMGMRYFDQVPGGSILSRLTNDTMSFSNFWALFNTLFTAFFAVITSFLAMYFTDRKISLWLLIFMPFLGVVIWYYQRYSSKVYRRMRERLSELNTKLSEAITGISVIQQFRQEHRINDEFDTTNNAYFKTRQAMIRTNSLLLSPIIDLFYALGTVMVLGVFGIRGLDGYVAAGMVYAFVTYLDNFYNPLTRMMDNLSDFQDGIVAGSRVLKVMDDQTMAPTQHPVEGLKITEGKIEFKHVTFAYDGVNPVLKDVSFVAKPGQTIALVGQTGSGKTSTINVLMRFYEFQSGEILIDDRDIREYPTAELRKKFGLVLQEPFMFYGDINSNIRMFDESISDEQVRDAAKFVMADDFINNLPQNYRSRVIERGASYSSGQRQLISFARTIVTDPKILILDEATANVDTETEEMIQTGLQKIQENRTTIAIAHRLSTIQNADLILVLNQGKIVERGDNEELMKQRGYYYDMIQLQNTDDKDNK
>NZ_CP019323.1|WP_076618201.1|2377549_2378515_-|ABC-transporter-substrate-binding-protein
MKKYLMGLITLIMATTLLAGCKTSASDNKTLDVGILQIVQHGSLDAARSGFKSGLNEAVKKHDKSMKVKYTYMNAQGDQSNVTSMSQQLTQKKPDLLLAIGTQAAQGLAKKTKDTPIIVTAVTDPKSAGLVKSNEKPQTNVTGASDISPVGKQIKLLKSITKNDKPIGIMYNSSEENSVLQVNLAKKYAKKHNIKIKTVSVTSTNDVASAVSGMKDSVSGIYLPTDNLMASSMKTIGKKAKEASLPVVTGSIEMAQDGGTATYGINYKDLGKQAGEMAYQVLVNKKDPKSMAIETSKTLRLYVNKANAKAIGIDSASITKP
>NZ_CP019323.1|WP_076618198.1|2376546_2377524_-|ABC-transporter-permease
MFISSLGQGLLWAPLVIGVFITFRILDIPDLTTEGSFPLGAATTISLMIHGQSTLIATIAGFVVGCVAGIVTGVLDTKLKIPSLLAGILTMTGLYSVNMHIMGKSNVPLLDQKVLTSYLPESLSSDIQTIIIGLIIVAIILGLLYSMFKTRLGLSLMATGNNKSMSAANGIQTDRMIIFGYMISNGLIALSGSLIAQSNGYADIGMGIGTIVIGLASVLVGEIFFRGRKILVRLLAMVFGAIIYRLLLTIAMGLGFPPDDLKILSAVILIIVICVPIVQNRIKTKKQLKEYLSELSKGETYGQSEEIRNIGSKKFTKGILSGNRE
>NZ_CP019323.1|WP_076618194.1|2375846_2376623_-|ATP-binding-cassette-domain-containing-protein
MDKAKKSEILVVKNLQKVFFPGTENEKHILKNINLKIYNGDFISVIGNNGAGKSTLLNTIAGTLSADAGEIDLDNHNIVNKSIAYRARFMSRVFQDPKMGTAGDLSVAENLVLAQKHTHTASLHRFKTADKWVEFKKLLKTLNMGLENRLETQVKYLSGGQRQALSLLMATLSKPDLLLLDEHTAALDPKTSFDVMDITQSIVQREKLTTMMITHKMSDALKYGNRLIMVQDGQIKLDVSGLDKENLKSEELIQLFQE
>NZ_CP019323.1|WP_076618191.1|2375090_2375780_-|NAD(P)H-dependent-oxidoreductase
MKTLIIVSHPEIDNSQTQQFLKKGSEEVDTTWHHIESLDKIDVLAEQKLLKNADRIIFQFPLYWYAAPFGLKKWEDEVLTRNFIYGDGTYPLKDKEFGLVVTTGMPLKDFQHGAKENITLDEAMAPYRAIAHLGKMKILTVFSVPQFWYMDEDRQMQLLIDYERYLSQKMPDSLLNREEWFNDRLNKFVSKLDDGDKFTGNLILDTFTNNKEDLSQLNDTLKMIKNGEE
>NZ_CP019323.1|WP_076618187.1|2374889_2375069_-|hypothetical-protein
MDEQSSWLIDQINQLKDKQVKYEDRAFLSALKQVVIEQSTRTDQIQHELDGRLWNHDKW
>NZ_CP019323.1|WP_076618183.1|2374098_2374710_-|WxL-domain-containing-protein
MKNLIKGTAVLGAIVVGAASTFLTVGAATTDAAETSPAPTTTNSTATITQTGALNLDSAPSIDFGSQAYTVGETKYASSAIGSDLHVTNPGFASGWSVTVSATPFTDSATSNTLKGTTLSLDSSKAAPITADDSSNVSGLPSYVAPLTIGSSATEVESAGAGDGVGAYSTSYGAADASLNVPAGNLPGTYSSTLTWTLNDAPA
>NZ_CP019323.1|WP_076618180.1|2372983_2374000_-|DUF916-and-DUF3324-domain-containing-protein
MLKKIFLPMILGLVSIFLLFTVGSTSVKADTLNYTVGADLPDNQIEKSGSYFNLKVTPGQSQDLTIKITNKDTTSHQYEVSINRGLTNQNGIIDYGTHGSEEKDGLEYNIESLVDDPQNVTVDGNSTKLVTLHLNAPKQAFSGIILGGIRVKELTSTSKNSSKKGLTINNQYAYVIGLELRQNSDKIKPKLQLGDISEKQYNYYNYVSANLINPTPSIIDNLSINATVKNTKGKNVYTQNKTNLSMAPNSDFGYLIGSPKQTLKAGNYELVMDAKSGSTIWHFDRKFTITTATAKKLEKTTVAPKSSGPNYLLIAFIIAILLIMILVIFVYHKKYRKN
>NZ_CP019323.1|WP_076618175.1|2371979_2372837_-|SDR-family-oxidoreductase
MKYIITGATGHLGSQILKEIVKLVPNSDISVGVHTPSKANLIASMGIEVLPIDYNNETMMISALTGKDILVYVPSKSHDSFSRVSELENVIKAAEKSGIGHILAMGFIADQENNPFDLSAFYGYLPRRLAESKLKFTIIKNALYADPLIPYLPELIERKNVIYPVGNEALSFISLEDSAKAFAKVAVTDELRQDGKIYTLTQDRNYTMVELADVLSEVSGHKIGYQPVTLQKFSDLYDQNGEGNMLSSMYRAGAMGLLDTVTDDYQEILGHSATDLSEFLTLKLN
>NZ_CP019323.1|WP_076618170.1|2371368_2371815_+|Rrf2-family-transcriptional-regulator
MRVSTRFSDSIHILAFIEIYKDIRLSSEVIASSVETSPVVIRRLMGVLREAGLIATKQGSAEPKLAREPKDITLLDIYFATEGNKPLFELDKKTNPECIVGGNIQDVLGDYYEQAKISAQRKLNDTTLQDLIETILVKQKAKEIANRV
>NZ_CP019323.1|WP_125673064.1|2382814_2385001_-|hypothetical-protein
MSITTTFIIDNHIVSAAKLSDPADLNNAINTAPQGLDIKNGAFVVGTFGNNSAKVIDRNKTPDDKTGILQITSAANQLGSIWGDINKDNYIDLNNNQTLSMWLYFGRPVDPSLPAGVGDGMAFVLQNSGIDAISRYTGPKPSHNPSAVNKLGIGESMGVWGTDFNYDHGATSTTSIAKTAIQKSWAMEFDTFLNKATNYDDISGEGFSFDNLQNGQHIGANYPDSPSSYRQQTAYDYHSTGTPLARDYYVLSHDGPGSLSLTDANWHHITYNWNAATETMNYSFNDKKLDGTHINDAYTGSYQIDPSHFKLSDNKLRWGFTGSTGKYFENNLVVFESIPSFVSADSSVSIKDNTLDKVLSTSDNYVDAGDDLSFIYNLNFESGSKEWENILASMNLPSQVSFESASIKYGDDPNVEVIPASEFSNSSVQHLLQRNLSNSNKQATIEIHTKVKPVTSAVSVPKSHASFKGDNFIIDDDAQAFNIRYKDISTLNLSTDVEGTINYDNLMSAPETTVINGLVKNSTGKVIDNSTTDVHTELNGVKQSYKLNGQNPGEFVVNVKRSDLIAGKNTLTIYAEDVSGKKSNEIKIIFDIGGGLTFGVVNDVSFKTINQGLKDQLVQRQSGWRVEVVDGRTPGQSWDLQAKADNLYSDNDTKLNGNLVFKDEDGNLSSLIDYQSVKTHIKNITDVQTIDVAGLWTKNAGILLQMNEVNPSGKYTGKIHWNLIDSVH
>NZ_CP019323.1|WP_076618210.1|2385322_2386507_+|MFS-transporter
MNSKKISPNLILMSLAISAFAIGSTEFISVGIMPILTETFNISLAKGGLTVSIYAAGIMFGAPILTLVTNRWNRKKLLIGIMVSFVIGNLIAALAPTFLILLLGRIITALSHGIFMAIASLIAADVVTPDKRASAIAVMFTGLTVATVTGVPLGTFIGQNINWRASFFFLVILGLIGLITNIILVPNNLPLPRKTNVKGIWKIIKQPELLLILLITALGYGATFPVYTYLTTILNKNMGWSESAIVIILIFYGLFVAIGNTLGGRFANKEPLSALLKMLLGLGIALILVRLTMNMHFLGLIATLIMGLFAFMNVPGLQLYIVQLAEKFTPNEISLASALNISAFNVGIAVGSSLGGNAVSANQLVNTPWLGVGMLIIGIILIIVLQKRIKANNQ
>NZ_CP019323.1|WP_076618213.1|2386569_2386959_+|helix-turn-helix-transcriptional-regulator
MKQSIYNIGVEATMNIIGGKWKPIILCHLKHQTMRTGQLRRAIPNITQKMLTQQLRELEDDGIVDRKVYNQIPPKVEYSLTQYGDSLNRILEELCLWGEENIERRKQNGENIILLKSENVETQDLPNVE
>NZ_CP019323.1|WP_076618216.1|2387065_2387500_+|ACT-domain-containing-protein
MEKYYIVDSSILPESFDKVIKARELLETGKSNNVSEAVKIVGISRGTYYKYKDLVFLPDDNMTDRKALISMMLNHEQGILAKAIAIISETNASILTINQNIPIHGIASVVISIDVSHLTGTIDDLMDKLKQTDNINNVQLISVE
>NZ_CP019323.1|WP_157886456.1|2387500_2387653_-|hypothetical-protein
MNFLTMALTFIIGLSFLLSASHVKSNKISKFLYCIGTFGIVMAMYIAWPK
>NZ_CP019323.1|WP_076618974.1|2387880_2388711_-|aldo/keto-reductase
MKTFKLNNGIEIPAVGFGVFQIENGGTKKAVLDAIDAGYRLIDTAQAYGNEAEVGEAIKESSVSRKDLFVTTKVWISSTGYDATKAAFEDSLNKLQLDYLDMYLIHQPYGDVYGSWRAMEELQKQGKVRAIGISNFTADRFVDLNKHNEVTPQVNQVEINPWNQQSDEIDWNKKTNIQPEAWAPFAEGKHNLFTNEILSGIGKKYDKGVGQVVLRWLFQRGIISLAKSVHKDRMEQNINIFDFSLTDEEMKQISSLDMKESAFFDHRDPTMVQNLD
>NZ_CP019323.1|WP_076618977.1|2388818_2389241_-|MerR-family-transcriptional-regulator
MNSKKVSELMDLTVDTLRYYERIGVIPPVDRDKNGYRDYKTNDLNWIFLAKNLRAAGLSIESLAEFASLAESKEDVKGAQKEILNEQMENLNEKLSDLQRTKDLLQYKIDTYDDHIAKFKSGELDKDNTEELWTMKHFKK
>NZ_CP019323.1|WP_076618219.1|2389309_2390638_-|MFS-transporter
MQKQEFGIVLPIVLLSYFMIVLDNSIIFTSTAKIAENLSLDTQSLAWITNAYALTFGGFLLFSGKAGDIIGRKKFFQIGLVLFSVSSLLVGISVNAEMIIAMRAIQGIGSSILAPSTLALLMDNYSDDMRTKAIAYYGTIGGLGASFGLIIGGMITTYSSWRIGFIINVPIGLILLLLSYRYLKTSKVYNQKLDFIGTILSILGISALVYSINGTSYRQISLIVSIISLILFVLYESRSDKPIMPLVLFKDKERSFAYLTRFFFVGASISYFFLTPLALQSVYGFTPLQAAIGFLPETIPQFIAATLVARMVNINVSKTISVGTILVFVGSLLAALVKIQSSYWIAIAIPMVIMGIGQGLALGILTVAGVAHTTPKLSGSASGIVNTVHQIGGSVGLSAVVALTSQYKGPVTSYNMSMVWITVISAIAMICAIGIIQADKKI
>NZ_CP019323.1|WP_076618224.1|2390812_2391400_+|TetR/AcrR-family-transcriptional-regulator
MTKRELAAATTRENLLETAENLLQQKGYEKMSVSDITKASGVAKGTFYNYFDKKEDIIFELNKRHMHNLSGQLIELSQGKPDESIRYYLNNFLQTIVDSKVNMARQWVRFITASSNQEKWQYDKGLLKKLINHLIDNGKLKQNTPVDDLTSLLITEVYGIILSWCITPETIEPVQTINKFCDLQLDFLLKPYIND
>NZ_CP019323.1|WP_076618227.1|2391474_2392047_+|flavodoxin
MNNITTGYGAISDGKDTNANVDPTRILDNNTKILIIYFSRSGNTEKQAKLAQDVLNSDIFELTVSNPYPSNYKATVNRATNERDAKNWPELNSDIPNLDKYDTILLGHPIWAMTIANPMREFLEEYGTLLSNKSVASFSTNDGYGSGETNDVISRLTTGSTKLLTNYTIRDTMAKQDRTNFINWLKKINK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP019323_18

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019323_18

2471625-2471747

Orphan

Consensus_repeat	Method
AAACGCGTGACAAAACGCAACTTTTTCCGTTTAGTTCAAAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP019323_18

>merge|NZ_CP019323|18|2471625-2471747|CRISPRCasFinder
AAACGCGTGACAAAACGCAACTTTTTCCGTTTAGTTCAAAAAGTTTGTGCATAACTTTTTTTCTACTCAAACTTGCGGCTGAAACGCGTGACAAAACGCAACTTTTTCCGTTTAGTTCAAAAA

>NZ_CP019323|18|18|2471625-2471747|CRISPRCasFinder
AAACGCGTGACAAAACGCAACTTTTTCCGTTTAGTTCAAAAA	GTTTGTGCATAACTTTTTTTCTACTCAAACTTGCGGCTG
AAACGCGTGACAAAACGCAACTTTTTCCGTTTAGTTCAAAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019323.1\|WP_076618418.1\|2461986_2462184_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_076618467.1\|2475912_2476734_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_CP019323.1\|WP_076618460.1\|2473467_2474529_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|236863
NZ_CP019323.1\|WP_076618477.1\|2479023_2479647_-\|DUF3862-domain-containing-protein	unknown	unknown	gnl\|CDD\|289729
NZ_CP019323.1\|WP_076618443.1\|2470602_2471184_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP019323.1\|WP_076618422.1\|2462263_2463466_+\|bifunctional-phosphopantothenoylcysteine-decarboxylase/phosphopantothenate--cysteine-ligase-CoaBC	unknown	unknown	gnl\|CDD\|235513
NZ_CP019323.1\|WP_076618448.1\|2471223_2471418_-\|PspC-domain-containing-protein	unknown	unknown	gnl\|CDD\|377200
NZ_CP019323.1\|WP_076618452.1\|2471824_2472655_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_CP019323.1\|WP_076618426.1\|2463547_2463958_-\|amino-acid-decarboxylase	unknown	unknown	unknown
NZ_CP019323.1\|WP_076618470.1\|2477418_2478108_-\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|212030
NZ_CP019323.1\|WP_120270431.1\|2463957_2464533_-\|UbiX-family-flavin-prenyltransferase	unknown	unknown	gnl\|CDD\|223241
NZ_CP019323.1\|WP_076618415.1\|2459221_2461921_-\|glycoside-hydrolase-family-3-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|224389
NZ_CP019323.1\|WP_076618456.1\|2472774_2473464_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NZ_CP019323.1\|WP_192844196.1\|2478387_2478936_+\|YitT-family-protein	unknown	unknown	gnl\|CDD\|376838
NZ_CP019323.1\|WP_076618436.1\|2466119_2466998_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP019323.1\|WP_076618487.1\|2482364_2482934_+\|DUF5067-domain-containing-protein	unknown	unknown	gnl\|CDD\|374759
NZ_CP019323.1\|WP_076618433.1\|2464548_2466024_-\|UbiD-family-decarboxylase	unknown	unknown	gnl\|CDD\|376697
NZ_CP019323.1\|WP_076618440.1\|2467222_2470261_-\|MMPL-family-transporter	unknown	unknown	gnl\|CDD\|225272
NZ_CP019323.1\|WP_076618464.1\|2474538_2475870_-\|M20/M25/M40-family-metallo-hydrolase	unknown	unknown	gnl\|CDD\|349930
NZ_CP019323.1\|WP_076618482.1\|2479726_2481655_-\|Dam-family-site-specific-DNA-(adenine-N6)-methyltransferase	unknown	unknown	gnl\|CDD\|225927

Protein	Function_ID	Function_description	E-value
NZ_CP019323.1\|WP_076618467.1\|2475912_2476734_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	9.56115e-104
NZ_CP019323.1\|WP_076618460.1\|2473467_2474529_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|236863	PRK11153, metN, DL-methionine transporter ATP-binding subunit; Provisional.	9.58907e-166
NZ_CP019323.1\|WP_076618477.1\|2479023_2479647_-\|DUF3862-domain-containing-protein	gnl\|CDD\|289729	pfam12978, DUF3862, Domain of Unknown Function with PDB structure (DUF3862). Structure 3D4E shared structural similarity to beta-lactamase inhibitory proteins (BLIP) which already include 1XXM, 1S0W, 1JTG, 2G2U, 2G2W, 2B5R, and 3due. All of structures are involved in beta-lactamase inhibitor complex. (REF http://www.topsan.org/Proteins/JCSG/3d4e).	1.70782e-14
NZ_CP019323.1\|WP_076618443.1\|2470602_2471184_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.10818e-09
NZ_CP019323.1\|WP_076618422.1\|2462263_2463466_+\|bifunctional-phosphopantothenoylcysteine-decarboxylase/phosphopantothenate--cysteine-ligase-CoaBC	gnl\|CDD\|235513	PRK05579, PRK05579, bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated.	0
NZ_CP019323.1\|WP_076618448.1\|2471223_2471418_-\|PspC-domain-containing-protein	gnl\|CDD\|377200	pfam04024, PspC, PspC domain. This family includes Phage shock protein C (PspC) that is thought to be a transcriptional regulator. The presumed domain is 60 amino acid residues in length.	1.17082e-13
NZ_CP019323.1\|WP_076618452.1\|2471824_2472655_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	4.48094e-98
NZ_CP019323.1\|WP_120270431.1\|2463957_2464533_-\|UbiX-family-flavin-prenyltransferase	gnl\|CDD\|223241	COG0163, UbiX family flavin prenyltransferase [Coenzyme transport and metabolism].	2.23607e-95
NZ_CP019323.1\|WP_076618470.1\|2477418_2478108_-\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|212030	cd00118, LysM, Lysin Motif is a small domain involved in binding peptidoglycan. LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.	4.87634e-06
NZ_CP019323.1\|WP_076618433.1\|2464548_2466024_-\|UbiD-family-decarboxylase	gnl\|CDD\|376697	pfam01977, UbiD, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase. This family has been characterized as 3-octaprenyl-4- hydroxybenzoate carboxy-lyase enzymes. This enzyme catalyzes the third reaction in ubiquinone biosynthesis. For optimal activity the carboxy-lase was shown to require Mn2+.	4.27357e-130
NZ_CP019323.1\|WP_076618415.1\|2459221_2461921_-\|glycoside-hydrolase-family-3-C-terminal-domain-containing-protein	gnl\|CDD\|224389	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism].	7.42592e-54
NZ_CP019323.1\|WP_076618456.1\|2472774_2473464_-\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	8.17154e-93
NZ_CP019323.1\|WP_192844196.1\|2478387_2478936_+\|YitT-family-protein	gnl\|CDD\|376838	pfam02588, YitT_membrane, Uncharacterized 5xTM membrane BCR, YitT family COG1284. This is probably a bacterial ABC transporter permease (personal obs:Yeats C).	1.13853e-26
NZ_CP019323.1\|WP_076618436.1\|2466119_2466998_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	3.31105e-45
NZ_CP019323.1\|WP_076618487.1\|2482364_2482934_+\|DUF5067-domain-containing-protein	gnl\|CDD\|374759	pfam16729, DUF5067, Domain of unknown function (DUF5067).	2.15355e-15
NZ_CP019323.1\|WP_076618440.1\|2467222_2470261_-\|MMPL-family-transporter	gnl\|CDD\|225272	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only].	6.72847e-117
NZ_CP019323.1\|WP_076618464.1\|2474538_2475870_-\|M20/M25/M40-family-metallo-hydrolase	gnl\|CDD\|349930	cd05681, M20_dipept_Sso-CP2, uncharacterized M20 dipeptidase. Peptidase M20 family, unknown dipeptidase-like subfamily (inferred by homology to be dipeptidases). M20 dipeptidases include a large variety of bacterial enzymes including cytosolic nonspecific dipeptidase (CNDP), Xaa-methyl-His dipeptidase (anserinase),and canosinase. These dipeptidases have been shown to act on a wide range of dipeptides, but not larger peptides. For example, anserinase mainly catalyzes the hydrolysis of N-alpha-acetylhistidine while carnosinase degrades beta-alanyl-L-histidine. This family includes Sso-CP2 from Sulfolobus solfataricus.	0
NZ_CP019323.1\|WP_076618482.1\|2479726_2481655_-\|Dam-family-site-specific-DNA-(adenine-N6)-methyltransferase	gnl\|CDD\|225927	COG3392, COG3392, Adenine-specific DNA methylase [DNA replication, recombination, and repair].	5.39032e-65

>NZ_CP019323.1|WP_076618448.1|2471223_2471418_-|PspC-domain-containing-protein
MHIPIKRSKNNQLIGGVVAGFCEKYDWDPAIGRVLYVILSLTPVFPGIIAYLVLWLLMEQPDMN
>NZ_CP019323.1|WP_076618443.1|2470602_2471184_+|TetR/AcrR-family-transcriptional-regulator
MKIDVTQHLTLGATRTLKAFREAMFETLGEKEFDKITVNDICKKSEYPRATFYNYFDDKYDLLQYLWSYIGKDILSKIPKNITEEKGIIKIFNLLLDFFNDHQELLTNVTKNNGVNSHLWHSMSGYLRHEANILVYEYSAENDQVKVPVKLLARFYSDLIIAVLEWCLFEQPNIDKKTADKYLTSLLNGGFTA
>NZ_CP019323.1|WP_076618440.1|2467222_2470261_-|MMPL-family-transporter
MKRITKKYTLALVGWIIVVLVAILAMPNVSQLVRDKGNITLPSYVESQQASRIEKKANGNKSVRTYTAVFNNNGNNKFTAAQSKKITHKLSKLENKNSLTIQKVMSPSENAQTKKQLISKDKSTQLAQITVNSSGTVSKQVNELQKQLKMDGVKTYVTGSDALNDEFTSVTEKGIQKTEVIAVIFIFIVLIIVFRSPIVPLISLLNVGVAFVTSLSIIMNLAQKYNFPLSNFTQVFLVVVLFGIGTDYNILLYNYFKGALARGMSAVEAAHDAQRHGGRTILYSGISVLIGFSVLSLAKFSFYQSAVGVAIGILVLLMVLLTLNMFFMETLGAKMFWPSKISGARGKSRLWYGLSRSALAYPVVILAIIAIVGVPFLVNSNTTLNFNNADEVPNSYEAKKGYEVIQDHFSKGMSAPVTIYIQNSKKLDTQSRLAAIDDLTQYLKKEPGVKTVASATQPGGDKIKSMYLKSQLTTITDGLKTSSKGIQEIKSGLNSANSQLTSANISGSTAQVQELADGTSQLQTGAQTLSSGIDQYTSGVSQVNSGLQSASSQMPTLTSGVSTLTSSSQQLSSGLSQLQSQMTALSSQATQILTLLAASGQDTSTAAAEMTQLQGAIGQLSTGSSAVSSGMSQLQNQIPTLTAGMSTLSSGTSTLVASNSTLTSGGQSVASGATQVNTGVQEMNTQLQSMATQVTQLQSGLSSASDGLDSLASGNATMKTYLDGLRTSYVGNTFYLPKDTIKSSEFKPALDNYMSSNRKIASITLVFKGDPNSDKTSKQLKTIQSDTDARLKHGVLKNATVAFGGQTSENNDTRKLANGDFGRTALIMTIGIGIALIVVTESILQPMTIIGTLLLAYEISLGITRVVSKFVLGDALLSWNTPFFTFIMLMALGVDYSIFLMVRFRDETDHDLKDRMLNAATAIGAVVISAAIILSGTFAALIPSGVTTLIQVALGVIFGLIILVIFLPLTLSSLISLTMWHENRMHRTKKPDKNIEQVKSSDDDDDKADSTK
>NZ_CP019323.1|WP_076618436.1|2466119_2466998_-|LysR-family-transcriptional-regulator
MNIHRLEIFVDLSKTFNYTDTAENFYTTQSNISKQILSLEKELSVSLFKREHRKIELTNEGRIILPHAQKIIDDFTNLQHDLNDYQDAKNLTIEMYTIPTMPNYQSFNLITQFLKQHPEIHVQLKEEESNNLFTALKSDKCEMIFARTFSFDDDKLEYIPMEFDSFVAVLPKHHKYAKLNKLDIEDLAHDNFLILGKSTNLYTPVTDLCHNAGFNPKVMYEGSRVDLIMQMVENNMGISILMEKTVKSFKNNNFVTVPITSNVENELGFFRKKGKHSEASEVFWKFIKNNIK
>NZ_CP019323.1|WP_076618433.1|2464548_2466024_-|UbiD-family-decarboxylase
MTDQPYDLRKVIEELKQQPGQYHETNVEVDPDAELSGVYRYIGAGGTVERPTREGPAMMFENVKGFPGTRVLIGAMASRKRDGMILHHDYKTLGRLLKDSVENPVKPVKVSKKDAPSQEIVHLATDKDFDIRKILPAPTNTEYDAGPYITMGVVFGSDPDKTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEKLNKPMPITINIGLDPAITIGATFEPPTTPLGYNELWVAGALRNQPVQIVDGVAVNENAIARAEYVVEAEIMPNETMQEDINTNTGKAMPEFPGYDGDANPAVNVVKVKAITHRKDNPIMQTTIGPSEEHVSMAGIPTEASILELVDRAIPGKVVNVYNPPAGGGKLMTIMQIHKDSEADEGIQKQAAILALSAFKELKTVILVDEDVDIFDMNDVIWTLNTRFQGDQDIMVLPGMRNHPLDPSERPQYDPKSIRFRGMSSKTIFDGTVPFDMSDQFKRASFKKVSDWKKYLE
>NZ_CP019323.1|WP_120270431.1|2463957_2464533_-|UbiX-family-flavin-prenyltransferase
MPNRKKKIVIGVTGASGTVYAIDLIKKLKKVPNVETHGIFSAWAKKNLQLETDYSLEEIRNMLDFYYNDSDLGATIASGSFLTDGMVIVPASMKTVASIAVGIGDNLISRAADVTLKEQRKLIMVPRETPLNTIHLENMTKLSKMGVQMIPPIPAFYNHPKTIQDLVDHQTMKIFDALGIDSESTGRWEGI
>NZ_CP019323.1|WP_076618426.1|2463547_2463958_-|amino-acid-decarboxylase
MPRFNITKENYTMTANVSTIGKDILIEVIGGDNPHIGTVTTLTSDTDMQTIRFPSHDGRLHKDDVLAKRIGTIIQSKLPGSCTISSGVHVNHISQKQIMVSSSMANDLGKQILSWLDSYDFDMPDPIYYTDSKNPV
>NZ_CP019323.1|WP_076618422.1|2462263_2463466_+|bifunctional-phosphopantothenoylcysteine-decarboxylase/phosphopantothenate--cysteine-ligase-CoaBC
MLKGKHITIYVTGGIAVYKSLNIVRELIKNQAEVQVVMTKAAQKFVTPLTFATLSQRPVLTDNFSAQSSQDDFIPHIKLARWTDLAVVVPATANIIGKLANGIADDLTSTTLMATDSPKLIFPTMNTTMWENPAVQNNINKLSLMDIKIVDPDSGFLAEGESGKGRLPELNTIMVEIFKMFTKPVLAGVNVIVTAGGTKEALDPVRFIGNNSSGKMGIAMANVAADMGAHVTLISTVHDYLNSPNIDEIQVNTAVEMKESLEKVFPKNDVLIMAAAVSDFRPMHKSTQKIKKDADKDLYTIQLQKNPDILKEISKKKDKQFVVGFAAETENLIPYAKKKLYEKNVDMILANDVSKAGSGFNVDTNEITLIRRDKEPETWPLMSKNDIAAKFWEYYDEHIK
>NZ_CP019323.1|WP_076618418.1|2461986_2462184_-|hypothetical-protein
MNTLTIDIILAMVLIVVINNPILSFLKQSMGLSFIFSEIIIAIIIIVIIYLINKFVIKRIMKYKK
>NZ_CP019323.1|WP_076618415.1|2459221_2461921_-|glycoside-hydrolase-family-3-C-terminal-domain-containing-protein
MEQSMSQREINNLNLSKKVAQDGMVLLQNENKALPLRNKKVALYGSGSFATVKGGTGSGDVNQRHVSSIIEGLEADNFEIANKSWLMRFQKYYDSKKKEYYDNLDDSLMSLLAPAFSMDDMEIGEFVDAPIGIYVISRSSGEGQDRKNEKGDYQLTDNELSNIKLFSEYYQKSILLLNVGGVIDTDFIEKCPLLDSVLLISQPGMAAGEAVAEVLDGSVIPSGKLTDTWAFNYEDYPSAKYFGEKNPRYNEGIYVGYRYFDSFNITPRYEFGFGLSYAKFLIDTVKISGNEQKIDVSINVQNSSETFSGKEVVQLYVSNPQSEISTPYQSLQAYAKTDLLKPSGYQKLNMSFDTKNLAVYDQKNAQLVMIPGTYLIRVGNSSRNTTVVGKLKLDEKVILRQFEHKLAPLVDPTEIKDNKVLLEQVGGVPFILLKAKNFEKAPEIKYTDYNEVKTYSSDEDTKLPGKGFNETIENVPELQQMKLIDVLHRKISLKEFVGNLSKQELIDLVEGSWKSNNSGSMVGNASQLVFGAAGETTGNKRVGIPATVNADGPAGLRLSPEYKKDGKTHFQYATAWPIGTMLAQTWNQDIVKQVGVAIGNEMKEFGVTMWLAPGMNIHRNPLGGRNFEYFSEDPLLSGTMATAETLGVQSHTGIGVVIKHFLGNNQETKRNTGDSIIGEQALREIYLKNFEIAVKSAQPMGIMSSYNKVNGIYSGENYELLTNVLRDEWNFQGLVMTDWFSLADPVHSMHSGNDLIMPGGSQDKLFSAVDNLRPEFDDDGSISIRKSFDVETFKQKYNNLWNDFELAADGDNYIRVNITEKINESMKRSILNGTVQIIDDNTLLLKGNWKDNNDLYIGDLQKSAMRILNVVMRTDRFAKENGLGEIKYNQNMELDSYFG
>NZ_CP019323.1|WP_076618452.1|2471824_2472655_-|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MNKKIKGIFAVLLTALSVFILAGCGNSSAANKVTTVKVGITGSDDRVWKAVNKKLAKENIKVKLVEFSDYSQPNTALDQGEVDLNAFQTVYFQNNWNKTHHTNIVSIGDTVIAPMALYSKKISNLSEIKEGDSIAVPNDATNEGRALQLLESAGLIKLDKAALPTPKDITENKLNLNIKQLDAAQTARSMGDVTASVVNSGVANDAKLNPKKAVYREKITAKSKPYVNIISANKKDKNNKTYKKIVKAYQSAEIAKKIKEVYGDYEKPAWNYKVLQ
>NZ_CP019323.1|WP_076618456.1|2472774_2473464_-|ABC-transporter-permease
MSHFINTYLPNVVENWEGDNGFVVAIQQTLYMTFVSAIFAGVIGIILGILLVVTTDDGITPHKVFYTTLDKLVNLFRSIPFIILLAVIGPFTKLIVGQTIGPTGALVPLVVGTAPFFARQVQLALVEVDKGVIEAAEAMGLSPIQIIFRVYLKEGLPELIRSGTLTTISLIGLTAMAGAVGGGGLGNMAISVGYQRFENDVTIVSMLLILVLVFVIQGIGDFAVRKLEH
>NZ_CP019323.1|WP_076618460.1|2473467_2474529_-|ATP-binding-cassette-domain-containing-protein
MVEKNGIVQLKDIDVTFHNEGKTIEAVKNVSINVQKGDVFGVIGYSGAGKSTLVRVINLLQKPTSGSVIVNNQNLTELSAKDLRKARKNIGMIFQHFNLMRSLTVFGNVAFPLRDSKLSKQERKDKVNNLLDLVGLADRANNYPSQLSGGQKQRVAIARALASDPEILISDEATSALDPKTTTEILSLLGRLNKELGITIVIITHEMDAIKQICNRVAVMENGELIEEGDLLTIFANPKKQLTKDFVNTSTQISNVLDEVKANGIVDSISGHLVELNFMGDVTNEPIIIELYKKFNIEANILFSNIERLQGTTVGIMLFDLEGEQNKIDKAIQYLTDLKINVKEIDLDESEGK
>NZ_CP019323.1|WP_076618464.1|2474538_2475870_-|M20/M25/M40-family-metallo-hydrolase
MSKLTDPLIQESIEELKQYIGLPSVSAKQQSIDETAEFLGNLLTEFGAKVDIWNDYKHPVVFAEAKPKKPSETTILIYNHYDVQPEEPVELWNSDPFELKITDDKFIGRGASDCKSDLISRITALKKYRQDHGDLPCNIKFLVEGEEEVASEHLAKYLEKYGDKLSADLVIWESGAKNEQEQFTFTGGNKGILCYELVATSSDIDLHSSFAAVVDSAAFRLSEAISALREKDGTIKVPGFYDDVVKPSKREEELVEKAVTPDLAKKWGLKVPLLNNKSVNYNLTFEPTINIEGISSGWEGEGVKTVTPKSATAKLEFRLVPNQDPKDIFDKLTKYLNDQGFKDIKVNYLLGEKGYRWDLDSPIVNKLISAAEDYYGGTDKVSALPSSAGTGPMYVVNKYTKAPIVSCGVSYAKGGAHAPNENIRIKDYLEFIDFFNEFLAKLN
>NZ_CP019323.1|WP_076618467.1|2475912_2476734_-|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKFKVTKVLLLAFTALFIFVLAGCSSQPKETTVKVGINPTDAPIWKIVKSKVKKEGINLKVTEFSDYNQPNTALSQGELDINAYQHKYFLDAWNKAHHTDIVPIGNTVIQPMAIYSSSIKNLSDLKDGDKVAIPNDASNESRALVLLENAGLIKLDNKTKLATVKNVSENKLNLKFTLLDAAQTARALDDVTVAVVNGNYASDAKLKPSAALYTEKINKSTKPWINFIAANKKDKNNKTYKKIVKAFQTKAVAKEIKKVYGGSAVPAWNTKL
>NZ_CP019323.1|WP_076618470.1|2477418_2478108_-|LysM-peptidoglycan-binding-domain-containing-protein
MKKVLSIALVSVMALTALGATTANTVDAATTADSTHVTVEKGDTYKSIAAENNTTISALEQANGREVGGFDLIYPGETITLPSATTDTTTDTTQATTQSVATEPAQTTQATDTTATDATQTATTDTTTQTAATTQTTSTTSSQGTFKISFYDPAVLGSNMGYSGVAANLSVFPKGTQLKITLADGTVMYRTVNDTGTFANTNSQQLDVAMPSSSIPSYGVTTATVEVVA
>NZ_CP019323.1|WP_192844196.1|2478387_2478936_+|YitT-family-protein
MILALELIAFSLNMFFEPNKVAAGGATGIAILLYEGWSIPTSLSVLLINIIMLIFSYFHLDKKTTIKLAFGSFLLPILLFITPVYNILPGNKIVSIIVGSIIFGIGLAILYTLDMSSGGTTVPPMIIHKNFGIDKYISLFIIDGFVCLGNIAMTGLLSFFLAVMSVAISSVAIKVFTIIEGK
>NZ_CP019323.1|WP_076618477.1|2479023_2479647_-|DUF3862-domain-containing-protein
MKIPFYKKKWFWISIISFFIIISTTAFVVENTYDDKADENLNQEDLFKKTKDSDTSIIDKFNKVKIGAKGNTLKRIEEVFGSPTITSNTSDRKNATLTWQNLKGLDDDVVIDITFQDGVAVSKSIKGLDIDRRNDLRLSDYNKVKENDSYDQVINLLGNPDNYIESGGVVTLTYTSDVEEKIDDASTYIEITLSNNKVTSKSQLNVK
>NZ_CP019323.1|WP_076618482.1|2479726_2481655_-|Dam-family-site-specific-DNA-(adenine-N6)-methyltransferase
MRFIGSKTRLLTQIDELLTKHLDGSEKTFADIFSGSNVVGEYFKTRYAITTNDLLYFSYALAKGEIDLNSQPSFTGLFKLNIHNPFDYFNQYDISNYSGDFITNNYSSAGKEKRLYFTVANAKRIDFIRVTIQKWLDNNDITSNEYFYLLASLIEAVPFVSNTTGTYGAYLKNFNDKRATKPLKLEPMKIHNNKQQNRAFNEDANELVKKIHGDIVYIDTPYNIRQYGSNYHLLETIARYDDPKIHGVSGVRDYTDLKSEYSAKNKAKETMQDLLDNLKFTHVLLSYSTDGIISEDELNEMIGQVAVDGSLEVIKIPFKKYNSRLNKDNNQLCELLYYFRTSHQEDNELLQIQSVKLPSDNSKYIKSPLNYTGGKFKLLPQLIPNFPKHIDTMVDLFSGGGNVGINVDAHQYYFNDVNDRIIDMFKYFQNNEFNDILDRINYQIDKYHLDKENEEGFLKLRDDYNNDPDPLDLYVLSSYSFNYQIRFNQDMKYNNPFGRKRSRFSNSMRENLRQFVTKLHTIDATFTSNYFSDFDTSHLTQDSLVYVDPPYLISDGTYNDGDRGFGNWTQQQENDLYDFLDALNDRNIKFAMSNVFKHKGHVNQTVIDWAIKYNIRHLNANYSQSSYHTNLLGTDEVLITNY
>NZ_CP019323.1|WP_076618487.1|2482364_2482934_+|DUF5067-domain-containing-protein
MKTKGLALTGLTILLASTLVGCSSGNDNSSKKESSNDNKTIKVAKKNTDKYYFKNNKLVTRDLSIQIIQNKVLSPGETGNDSDKPVIAFWYKVTNKTNKEIDANTAWIAIFKAVQDNNENTINELKVAALPDNQYLDSQASAIKKNGTVENAVAYTLSDTNTPVQLNATKGVDGKKLGTMKYELNYNEM

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP019323_19

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019323_19

2503094-2503195

Orphan

Consensus_repeat	Method
CAGATGCTCTACCAGCTGAGCTAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP019323_19

>merge|NZ_CP019323|19|2503094-2503195|CRISPRCasFinder
CAGATGCTCTACCAGCTGAGCTAACGACTCATGGATGGAGGATACAGGGATCGAACCTGTGACCTCCTGCTTGTAAGGCAGATGCTCTCCCAGCTGAGCTAA

>NZ_CP019323|19|19|2503094-2503195|CRISPRCasFinder
CAGATGCTCTACCAGCTGAGCTAA	CGACTCATGGATGGAGGATACAGGGATCGAACCTGTGACCTCCTGCTTGTAAGG
CAGATGCTCTCCCAGCTGAGCTAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019323.1\|WP_076618525.1\|2494000_2494321_+\|multidrug-efflux-SMR-transporter	unknown	unknown	gnl\|CDD\|224987
NZ_CP019323.1\|WP_076618535.1\|2497855_2498386_+\|dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|223340
NZ_CP019323.1\|WP_076618542.1\|2500168_2500486_-\|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl\|CDD\|223672
NZ_CP019323.1\|WP_076618539.1\|2498593_2500069_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019323.1\|WP_192844197.1\|2494317_2495136_-\|YdcF-family-protein	unknown	unknown	gnl\|CDD\|376902
NZ_CP019323.1\|WP_076618520.1\|2492055_2493240_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340883
NZ_CP019323.1\|WP_076618523.1\|2493396_2493819_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|236715
NZ_CP019323.1\|WP_076618530.1\|2495443_2497093_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227268
NZ_CP019323.1\|WP_076618516.1\|2490466_2491912_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|372624
NZ_CP019323.1\|WP_157886457.1\|2497107_2497749_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|380024

Protein	Function_ID	Function_description	E-value
NZ_CP019323.1\|WP_076618525.1\|2494000_2494321_+\|multidrug-efflux-SMR-transporter	gnl\|CDD\|224987	COG2076, EmrE, Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism].	4.13768e-28
NZ_CP019323.1\|WP_076618535.1\|2497855_2498386_+\|dihydrofolate-reductase	gnl\|CDD\|223340	COG0262, FolA, Dihydrofolate reductase [Coenzyme metabolism].	4.88522e-26
NZ_CP019323.1\|WP_076618542.1\|2500168_2500486_-\|carboxymuconolactone-decarboxylase-family-protein	gnl\|CDD\|223672	COG0599, COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown].	2.20339e-27
NZ_CP019323.1\|WP_157886457.1\|2497107_2497749_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|380024	pfam17802, SpaA, Prealbumin-like fold domain. This entry contains a prealbumin-like domain from a wide variety of bacterial surface proteins. This entry corresponds to domain 1 and domain 3 of SpaA from Corynebacterium diphtheriae. Some members of this family contain an isopeptide bond.	1.45431e-15
NZ_CP019323.1\|WP_192844197.1\|2494317_2495136_-\|YdcF-family-protein	gnl\|CDD\|376902	pfam02698, DUF218, DUF218 domain. This large family of proteins contains several highly conserved charged amino acids, suggesting this may be an enzymatic domain (Bateman A pers. obs). The family includes SanA, which is involved in Vancomycin resistance. This protein may be involved in murein synthesis.	3.96571e-44
NZ_CP019323.1\|WP_076618520.1\|2492055_2493240_+\|MFS-transporter	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.29612e-63
NZ_CP019323.1\|WP_076618530.1\|2495443_2497093_+\|hypothetical-protein	gnl\|CDD\|227268	COG4932, COG4932, Predicted outer membrane protein [Cell envelope biogenesis, outer membrane].	1.99567e-32
NZ_CP019323.1\|WP_076618516.1\|2490466_2491912_+\|amino-acid-permease	gnl\|CDD\|372624	pfam13520, AA_permease_2, Amino acid permease.	7.32891e-20
NZ_CP019323.1\|WP_076618523.1\|2493396_2493819_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|236715	PRK10562, PRK10562, putative acetyltransferase; Provisional.	1.18978e-30

>NZ_CP019323.1|WP_076618542.1|2500168_2500486_-|carboxymuconolactone-decarboxylase-family-protein
MKKQTAGQEQLGDFAPQFAKLNDDVLFGEVWSKESELSAHDRSMITIASIISAGNLEQLDAHLKIGKKNGITKEEIVAEITHLSFYAGWPKAWSAFNRAKEIWTE
>NZ_CP019323.1|WP_076618539.1|2498593_2500069_-|hypothetical-protein
MQFRTSKKWERVFFPIVFLYFFIFRFLVIPSGDDYFWGGSQGEYLMNHGFYGPQKIYGGSSNGRWIGNLSEIFTVHHLIFAMLAYAIFWTLLIWCIWKLTGRSKLSMILSGLFVFTFQDGYISTVLGWNAGFINYIPPLALILLFLTFIKDLYDGNRIYHPILLAICTFLMSLVGGLFVEHLTLYQIFIGVIAILCGIYIYHEKFQWFEGSYLLGAIVSAAIMFSHPAYHEKSTYRDTNFDLHGIINNYFYITHYWFNTLNIVVNIALCLAIIVIATHQLRNNKLKWFINIISVFFIIYYVTINIWLGQHNYDQFFMYQNLSIRITQIDGIMTIVYWLFLIFATICLFNAKSNYILYFSMFTYFALISPFIIIISPINSREFFTSYVFLYIATIIYVQKAASFYSRYMVKNLRTVATIVLLLCSINVGYKMVANYQANLIRVQDERFLSGKASLPNHVPYRKYVLSNDALLQQSSTYWKDFLNKSWLERLY
>NZ_CP019323.1|WP_076618535.1|2497855_2498386_+|dihydrofolate-reductase
MRKTVFYGAISLDGFLADDNYSLDWLFKYNDNKIMKESYEPFFKTVDTTVMGRKTFDDLLTITNEFPYKDTKNFVLSHRPIESKYIQQVNQPIEEFISELKKQPGKDIWIVGGGKIVSTLIENNLIDSLQIQITPDILGSGIKLFDHINNQPNFTTDYVKQFDDLIDIKYSLKASV
>NZ_CP019323.1|WP_157886457.1|2497107_2497749_+|LPXTG-cell-wall-anchor-domain-containing-protein
MGVAGAVYGLYNADGDIVGSYMTDKDGVIKVDNLPAGEYYFQETLPPDGYDINDEKIHFTITDKDIELGTLKTSDPKIKDTDDNNGEDDNDEDSNEEDNNGEDNNEEDNNEEDNNGEDSNEEDSNEEDNNDEDGDSGLITNPINPDENNNENNSSENTDESTVNPTTPQPPYEGNGDSSQTYLPQTSTDTGVLASIIGSLTLVTFLYFRRRKA
>NZ_CP019323.1|WP_076618530.1|2495443_2497093_+|hypothetical-protein
MGKKLRNILTIVLAAMGIFVAALCFNSTKVSAAAYTSNDLISSAQIINQDKNYSYSSTVGVQYNWDTTGTDISLKDGDTLTMELPEQLRAKSDAGVPFDITDDDGHVIGSAVVNSDNTVTVTFNENVETYHDVSGSITIGNGIGVSDSALAGNNEVEFPTMNGNQTSNMNVIPSENNISKKGVMSTDENGDHIITWTILANRQELDLKNMNVYEDVTQRDPEEYLEYVQGSVIVNKAHWTSNTSYKKDELVDSSNYTLTENSNGFHINIPDSANQMYAITIQTKIPADKATDGETVFKNQAQITWGKPGTDGETPRESASGSVTSDITGDNSGSGSGNVKGNVVLTKISDDSEYSLEGAVYDLYEVGNDVAIKTGLTTDADGKISISNLAPGEYYFKETTPPSGFQLNSNEIPFTITGDTTTPIQLTGRDDPISEPLGSILIQKLDLETGHKLNGAEFEITQTSGNEVGKTWTTTADDNGLYHVSDLPYGTYTIQETKAPDGYILDSSIREFTISAENPNPGLFTFDNDKETGTDPDFSASIKNLIPTN
>NZ_CP019323.1|WP_192844197.1|2494317_2495136_-|YdcF-family-protein
MAFAIATAIGSIVFLIINTNVMKSREGKTFTGQLSAIFGVNLAIILVFFYMYTRFNLPGYLEMIIFSVSWIDVIFSIIFFGYAGYSFIIQMMPKLSNANYIVILGAWIKDGAVTPLLKSRIDKGIQYYHGYSDTAKFVVSGGQGFDESISEAKAMRNYLISVGIPKDKIIIEDKSTSTLENMKNSRTLILADWKTENEPRVVFSTSNYHVLRASILANKVGMEADGIGAPTSLFFLPSAMIREFLAILKYYWWITGMIIIVIPLISFFFVSH
>NZ_CP019323.1|WP_076618525.1|2494000_2494321_+|multidrug-efflux-SMR-transporter
MNWIYLIIAGIFEVFWAYMMKLSHGFTKINFTVFTILGMLVSFILLAKATKTLPLSIAYPVWTGIGAIGSILVGFFIFGDKISPITWVFIILLLISIIGIKITTSN
>NZ_CP019323.1|WP_076618523.1|2493396_2493819_-|GNAT-family-N-acetyltransferase
MIEKITPNEIDSVADIWLEGNLDAHNFINAKYWKRNFPVVKERLNNAEVYVYKNDQDIAGFIGLNGNYIEGVFVKKEFRSKGIGKELFDYVKELHDDLIINCYVKNFKAINFYRVNGFSIKAEGIDKDTGESEITLIWRK
>NZ_CP019323.1|WP_076618520.1|2492055_2493240_+|MFS-transporter
MEKNKKSIYILIFSNFLICLGIGLVIPVTPFIKNEFHYTTSQMGVMTSLFAFAQFIASPIVGRMSDKVGRKPVIVLGLFTYMISEFIFAVATTLPIFNLSRIIGGLSAAMVIPTSMALGSDLTTLKDRAKVIGWLSAAFSGGLILGPGLGGILAGISYKTPFWVAGVLAITSCIFTQIFLKESRETIEIEHKEEAKLNKGKSSIISILTVPMVVLFGMILVSSFGLQGFESIYSIYVNQVFNFGLGTIALVLTLNGIISLILQVVAFNWLINKIGEMGLISYCFLLSAVCVFWITRAHTTVEVIVATLVIFSSFDLLRPAITTLLTKSSKANQGLINGMNMSLTSIGNVIGPLMSGALMDWNTHYPYIVVAIILIFSYFLTFIVKRFPLVSAEE
>NZ_CP019323.1|WP_076618516.1|2490466_2491912_+|amino-acid-permease
MNDLNMDPKPHYMKWQVIALLDFVTIISFENIFYPFQNQGLSVVVSWIFLLFAYVIPYELIVSQMSLTFDNQSGGLASWVRHGSNDTLGYWTSWMYWIQSVPYIVDVSNSVIVSFSWIIFGNNSLDRRMSTFSFGLLTFVIILIFILLENVFKNSLEVLSLIGGGAMFVMSVLFVLLAGYAVTHGAHIATQPMNWAAFKPTFSLKYFSTTGLLIFAMSGAELAAPYIVQMRDPKHEFPKAMWLLALMTAFLTIFGTLSLAVFFNANHIPHDFKMNGPYYAFHLLGQSLGVGKLLMYIFAVVQAIFMMAQLAVLLDASSRVFAGDVADKFMPKWLTKTNKNGRPIHSYTMTTGLSLFLLLLTGTLPNINTIYNWLLNINGIISPYKTCWVFFAFIAVRWQDKKFHSEYTFIKNRTGALLVGGWCLAFTFVCATLGFIPQEAAFGTKLFDHQLLLNFITVIVLFGMGFVMPILRKHEINKELN

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP019323_6	6.11\|601203\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	601203-601232	30	NZ_LS991422	Lactobacillus casei isolate CECT 9104 plasmid 2	210-239	5	0.833
NZ_CP019323_6	6.11\|601203\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	601203-601232	30	NC_030904	Bacillus phage vB_BhaS-171, complete genome	35644-35673	5	0.833
NZ_CP019323_6	6.11\|601203\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	601203-601232	30	NZ_CP029156	Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence	25701-25730	5	0.833
NZ_CP019323_6	6.11\|601203\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	601203-601232	30	NZ_CP029153	Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence	19745-19774	5	0.833
NZ_CP019323_6	6.11\|601203\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	601203-601232	30	AY855346	Clostridium difficile bacteriophage phi CD119, complete genome	42301-42330	5	0.833
NZ_CP019323_6	6.11\|601203\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	601203-601232	30	NC_007917	Clostridium phage phi CD119, complete genome	42301-42330	5	0.833
NZ_CP019323_6	6.11\|601203\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	601203-601232	30	LN681539	Clostridium phage phiCD505, complete genome	42484-42513	5	0.833
NZ_CP019323_6	6.11\|601203\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	601203-601232	30	NC_028996	Clostridium phage phiCDHM19, complete genome	45314-45343	5	0.833
NZ_CP019323_6	6.11\|601203\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	601203-601232	30	LN681542	Clostridium phage phiMMP03, complete genome	44273-44302	5	0.833
NZ_CP019323_6	6.11\|601203\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	601203-601232	30	HG531805	Clostridium phage CDMH1 complete genome	45636-45665	5	0.833
NZ_CP019323_6	6.11\|601203\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	601203-601232	30	NC_009231	Clostridium phage phiC2, complete genome	47810-47839	5	0.833
NZ_CP019323_6	6.11\|601203\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	601203-601232	30	JX145341	Clostridium phage phiMMP02, complete genome	42551-42580	5	0.833
NZ_CP019323_6	6.11\|601203\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	601203-601232	30	NC_011398	Clostridium phage phiCD27, complete genome	43362-43391	5	0.833
NZ_CP019323_6	6.11\|601203\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	601203-601232	30	NC_048642	Clostridium phage CDKM9, complete genome	44639-44668	5	0.833
NZ_CP019323_6	6.11\|601203\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	601203-601232	30	KX228400	Clostridium phage CDKM15, complete genome	44795-44824	5	0.833
NZ_CP019323_6	6.11\|601203\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	601203-601232	30	NZ_CP015354	Bacillus thuringiensis strain MYBT18246 plasmid p120416, complete sequence	95827-95856	5	0.833
NZ_CP019323_6	6.4\|600741\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600741-600770	30	KX961631	Bacillus phage QCM11, complete genome	8501-8530	6	0.8
NZ_CP019323_6	6.4\|600741\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600741-600770	30	NC_031015	Bacillus phage Claudi, complete genome	8829-8858	6	0.8
NZ_CP019323_6	6.4\|600741\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600741-600770	30	MT777452	Bacillus phage Baseball_field, complete genome	9212-9241	6	0.8
NZ_CP019323_6	6.4\|600741\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600741-600770	30	NC_049964	Bacillus phage KonjoTrouble, complete genome	8801-8830	6	0.8
NZ_CP019323_6	6.4\|600741\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600741-600770	30	MN082624	Bacillus phage VioletteMad, complete genome	8801-8830	6	0.8
NZ_CP019323_6	6.4\|600741\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600741-600770	30	NC_049962	Bacillus phage SerPounce, complete genome	8971-9000	6	0.8
NZ_CP019323_6	6.7\|600939\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600939-600968	30	NZ_CP038639	Cupriavidus oxalaticus strain X32 plasmid unnamed4, complete sequence	163799-163828	6	0.8
NZ_CP019323_6	6.2\|600609\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600609-600638	30	NZ_CP040842	Leptospira weilii strain CUDO6 plasmid pDO6, complete sequence	27572-27601	7	0.767
NZ_CP019323_6	6.2\|600609\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600609-600638	30	NZ_CP040842	Leptospira weilii strain CUDO6 plasmid pDO6, complete sequence	39560-39589	7	0.767
NZ_CP019323_6	6.2\|600609\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600609-600638	30	NZ_CP040845	Leptospira weilii strain CUD13 plasmid pD13, complete sequence	35714-35743	7	0.767
NZ_CP019323_6	6.2\|600609\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600609-600638	30	NZ_CP040845	Leptospira weilii strain CUD13 plasmid pD13, complete sequence	45811-45840	7	0.767
NZ_CP019323_6	6.3\|600675\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600675-600704	30	MN693539	Marine virus AFVG_25M73, complete genome	22661-22690	7	0.767
NZ_CP019323_6	6.8\|601005\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	601005-601034	30	NZ_CP020435	Bacillus sp. FDAARGOS_235 plasmid 3, complete sequence	6267-6296	7	0.767
NZ_CP019323_6	6.11\|601203\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	601203-601232	30	NZ_CP028328	Lactobacillus sp. D1501 plasmid p2, complete sequence	1945-1974	7	0.767
NZ_CP019323_6	6.12\|601269\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	601269-601298	30	MN693722	Marine virus AFVG_250M657, complete genome	39239-39268	7	0.767
NZ_CP019323_6	6.3\|600675\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600675-600704	30	NC_019848	Sinorhizobium meliloti GR4 plasmid pRmeGR4c, complete sequence	204776-204805	8	0.733
NZ_CP019323_6	6.3\|600675\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600675-600704	30	NC_003037	Sinorhizobium meliloti 1021 plasmid pSymA, complete sequence	232824-232853	8	0.733
NZ_CP019323_6	6.3\|600675\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600675-600704	30	NZ_CP019585	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymA, complete sequence	1194167-1194196	8	0.733
NZ_CP019323_6	6.3\|600675\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600675-600704	30	NZ_CP013109	Sinorhizobium americanum strain CFNEI 73 plasmid B, complete sequence	536584-536613	8	0.733
NZ_CP019323_6	6.3\|600675\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600675-600704	30	NC_017327	Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence	1376971-1377000	8	0.733
NZ_CP019323_6	6.3\|600675\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600675-600704	30	NZ_CP021798	Sinorhizobium meliloti strain USDA1106 plasmid psymA, complete sequence	490071-490100	8	0.733
NZ_CP019323_6	6.3\|600675\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600675-600704	30	NC_017324	Sinorhizobium meliloti BL225C plasmid pSINMEB01, complete sequence	1335971-1336000	8	0.733
NZ_CP019323_6	6.3\|600675\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600675-600704	30	NZ_CP009145	Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence	311513-311542	8	0.733
NZ_CP019323_6	6.3\|600675\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600675-600704	30	NZ_CP021128	Rhizobium sp. Kim5 plasmid pRetKim5d, complete sequence	202640-202669	8	0.733
NZ_CP019323_6	6.3\|600675\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600675-600704	30	NZ_CP021801	Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence	208302-208331	8	0.733
NZ_CP019323_6	6.3\|600675\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600675-600704	30	NZ_CP013053	Sinorhizobium americanum CCGM7 plasmid B, complete sequence	497163-497192	8	0.733
NZ_CP019323_6	6.3\|600675\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600675-600704	30	NZ_CP021824	Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence	187911-187940	8	0.733
NZ_CP019323_6	6.3\|600675\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600675-600704	30	NC_018683	Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence	438137-438166	8	0.733
NZ_CP019323_6	6.3\|600675\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600675-600704	30	NZ_CP021794	Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence	1170827-1170856	8	0.733
NZ_CP019323_6	6.3\|600675\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600675-600704	30	NZ_CP021809	Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence	187281-187310	8	0.733
NZ_CP019323_6	6.3\|600675\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600675-600704	30	NZ_CP021217	Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence	1543329-1543358	8	0.733
NZ_CP019323_6	6.3\|600675\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600675-600704	30	NZ_CP026526	Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence	201533-201562	8	0.733
NZ_CP019323_6	6.3\|600675\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600675-600704	30	NZ_CP019486	Sinorhizobium meliloti strain B399 plasmid pSymA, complete sequence	203786-203815	8	0.733
NZ_CP019323_6	6.3\|600675\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600675-600704	30	NC_020527	Sinorhizobium meliloti 2011 plasmid pSymA, complete sequence	232489-232518	8	0.733
NZ_CP019323_6	6.5\|600807\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600807-600836	30	KX077895	Streptococcus phage phiZJ20091101-4, complete genome	24595-24624	8	0.733
NZ_CP019323_6	6.9\|601071\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	601071-601100	30	MG250483	Aeromonas phage Ah1, complete genome	190455-190484	8	0.733
NZ_CP019323_6	6.5\|600807\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600807-600836	30	LR588166	Pseudomonas phage vB_PaeM_MIJ3	49622-49651	9	0.7
NZ_CP019323_6	6.5\|600807\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600807-600836	30	MH121069	Pseudomonas phage vB_PaeM_PA5oct, complete genome	166161-166190	9	0.7
NZ_CP019323_6	6.1\|600543\|30\|NZ_CP019323\|PILER-CR,CRISPRCasFinder,CRT	600543-600572	30	NC_048106	Synechococcus phage S-CBWM1, complete genome	106173-106202	10	0.667

1. spacer 6.11|601203|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LS991422 (Lactobacillus casei isolate CECT 9104 plasmid 2) position: , mismatch: 5, identity: 0.833

atttttaacgttctcaatgagtaatattga-	CRISPR spacer
gtttttaacgttctcaatgagtaa-gtagct	Protospacer
.*********************** .* *

2. spacer 6.11|601203|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NC_030904 (Bacillus phage vB_BhaS-171, complete genome) position: , mismatch: 5, identity: 0.833

atttttaacgttctcaatgagtaatattga-	CRISPR spacer
gtttttaacgttctcaatgagtag-ataggt	Protospacer
.**********************. ** *.

3. spacer 6.11|601203|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029156 (Clostridioides difficile strain CD161 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.833

atttttaacgttctcaatgagtaa-tattga	CRISPR spacer
atttttaacgttttcaataagtaagtactt-	Protospacer
************.*****.***** **.*

4. spacer 6.11|601203|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029153 (Clostridioides difficile strain CDT4 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.833

atttttaacgttctcaatgagtaa-tattga	CRISPR spacer
atttttaacgttttcaataagtaagtactt-	Protospacer
************.*****.***** **.*

5. spacer 6.11|601203|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to AY855346 (Clostridium difficile bacteriophage phi CD119, complete genome) position: , mismatch: 5, identity: 0.833

atttttaacgttctcaatgagt-aatattga	CRISPR spacer
atttttaacgttttcaataagtaaatactt-	Protospacer
************.*****.*** ****.*

6. spacer 6.11|601203|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NC_007917 (Clostridium phage phi CD119, complete genome) position: , mismatch: 5, identity: 0.833

atttttaacgttctcaatgagt-aatattga	CRISPR spacer
atttttaacgttttcaataagtaaatactt-	Protospacer
************.*****.*** ****.*

7. spacer 6.11|601203|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to LN681539 (Clostridium phage phiCD505, complete genome) position: , mismatch: 5, identity: 0.833

atttttaacgttctcaatgagt-aatattga	CRISPR spacer
atttttaacgttttcaataagtaaatactt-	Protospacer
************.*****.*** ****.*

8. spacer 6.11|601203|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NC_028996 (Clostridium phage phiCDHM19, complete genome) position: , mismatch: 5, identity: 0.833

atttttaacgttctcaatgagt-aatattga	CRISPR spacer
atttttaacgttttcaataagtaaatactt-	Protospacer
************.*****.*** ****.*

9. spacer 6.11|601203|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to LN681542 (Clostridium phage phiMMP03, complete genome) position: , mismatch: 5, identity: 0.833

atttttaacgttctcaatgagt-aatattga	CRISPR spacer
atttttaacgttttcaataagtaaatactt-	Protospacer
************.*****.*** ****.*

10. spacer 6.11|601203|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to HG531805 (Clostridium phage CDMH1 complete genome) position: , mismatch: 5, identity: 0.833

atttttaacgttctcaatgagt-aatattga	CRISPR spacer
atttttaacgttttcaataagtaaatactt-	Protospacer
************.*****.*** ****.*

11. spacer 6.11|601203|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NC_009231 (Clostridium phage phiC2, complete genome) position: , mismatch: 5, identity: 0.833

atttttaacgttctcaatgagt-aatattga	CRISPR spacer
atttttaacgttttcaataagtaaatactt-	Protospacer
************.*****.*** ****.*

12. spacer 6.11|601203|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to JX145341 (Clostridium phage phiMMP02, complete genome) position: , mismatch: 5, identity: 0.833

atttttaacgttctcaatgagt-aatattga	CRISPR spacer
atttttaacgttttcaataagtaaatactt-	Protospacer
************.*****.*** ****.*

13. spacer 6.11|601203|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NC_011398 (Clostridium phage phiCD27, complete genome) position: , mismatch: 5, identity: 0.833

atttttaacgttctcaatgagt-aatattga	CRISPR spacer
atttttaacgttttcaataagtaaatactt-	Protospacer
************.*****.*** ****.*

14. spacer 6.11|601203|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NC_048642 (Clostridium phage CDKM9, complete genome) position: , mismatch: 5, identity: 0.833

atttttaacgttctcaatgagt-aatattga	CRISPR spacer
atttttaacgttttcaataagtaaatactt-	Protospacer
************.*****.*** ****.*

15. spacer 6.11|601203|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to KX228400 (Clostridium phage CDKM15, complete genome) position: , mismatch: 5, identity: 0.833

atttttaacgttctcaatgagt-aatattga	CRISPR spacer
atttttaacgttttcaataagtaaatactt-	Protospacer
************.*****.*** ****.*

16. spacer 6.11|601203|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015354 (Bacillus thuringiensis strain MYBT18246 plasmid p120416, complete sequence) position: , mismatch: 5, identity: 0.833

atttttaacgttctcaatgagt-aatattga	CRISPR spacer
gtttttaacgttttcaatgaataaatattt-	Protospacer
.***********.*******.* ******

17. spacer 6.4|600741|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to KX961631 (Bacillus phage QCM11, complete genome) position: , mismatch: 6, identity: 0.8

aatgaagtactagttaagaactttaatatg	CRISPR spacer
actgaagtactagttgataactttactttc	Protospacer
* *************.* ******* * *

18. spacer 6.4|600741|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NC_031015 (Bacillus phage Claudi, complete genome) position: , mismatch: 6, identity: 0.8

aatgaagtactagttaagaactttaatatg	CRISPR spacer
actgaagtactagttgataactttactttc	Protospacer
* *************.* ******* * *

19. spacer 6.4|600741|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to MT777452 (Bacillus phage Baseball_field, complete genome) position: , mismatch: 6, identity: 0.8

aatgaagtactagttaagaactttaatatg	CRISPR spacer
actgaagtactagttgataactttactttc	Protospacer
* *************.* ******* * *

20. spacer 6.4|600741|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NC_049964 (Bacillus phage KonjoTrouble, complete genome) position: , mismatch: 6, identity: 0.8

aatgaagtactagttaagaactttaatatg	CRISPR spacer
actgaagtactagttgataactttactttc	Protospacer
* *************.* ******* * *

21. spacer 6.4|600741|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to MN082624 (Bacillus phage VioletteMad, complete genome) position: , mismatch: 6, identity: 0.8

aatgaagtactagttaagaactttaatatg	CRISPR spacer
actgaagtactagttgataactttactttc	Protospacer
* *************.* ******* * *

22. spacer 6.4|600741|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NC_049962 (Bacillus phage SerPounce, complete genome) position: , mismatch: 6, identity: 0.8

aatgaagtactagttaagaactttaatatg	CRISPR spacer
actgaagtactagttgataactttactttc	Protospacer
* *************.* ******* * *

23. spacer 6.7|600939|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038639 (Cupriavidus oxalaticus strain X32 plasmid unnamed4, complete sequence) position: , mismatch: 6, identity: 0.8

tggcgtcagcgtcaatgtttgccatgttgg	CRISPR spacer
acgcgtcagcgtccaggtttgccatgtttc	Protospacer
  *********** * ************

24. spacer 6.2|600609|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040842 (Leptospira weilii strain CUDO6 plasmid pDO6, complete sequence) position: , mismatch: 7, identity: 0.767

aaaacgttaaaaataaactgagtctcgtgt	CRISPR spacer
aaaaagttaaaattaaactgagtcaattta	Protospacer
**** ******* ***********   *

25. spacer 6.2|600609|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040842 (Leptospira weilii strain CUDO6 plasmid pDO6, complete sequence) position: , mismatch: 7, identity: 0.767

aaaacgttaaaaataaactgagtctcgtgt	CRISPR spacer
aaaaagttaaaattaaactgagtcaattta	Protospacer
**** ******* ***********   *

26. spacer 6.2|600609|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040845 (Leptospira weilii strain CUD13 plasmid pD13, complete sequence) position: , mismatch: 7, identity: 0.767

aaaacgttaaaaataaactgagtctcgtgt	CRISPR spacer
aaaaagttaaaattaaactgagtcaattta	Protospacer
**** ******* ***********   *

27. spacer 6.2|600609|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040845 (Leptospira weilii strain CUD13 plasmid pD13, complete sequence) position: , mismatch: 7, identity: 0.767

aaaacgttaaaaataaactgagtctcgtgt	CRISPR spacer
aaaaagttaaaattaaactgagtcaattta	Protospacer
**** ******* ***********   *

28. spacer 6.3|600675|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to MN693539 (Marine virus AFVG_25M73, complete genome) position: , mismatch: 7, identity: 0.767

ctagaactgctgacaaagcgacttttgaca	CRISPR spacer
cgaatactgctgacaaagatacttttgagt	Protospacer
* *. *************  ********

29. spacer 6.8|601005|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020435 (Bacillus sp. FDAARGOS_235 plasmid 3, complete sequence) position: , mismatch: 7, identity: 0.767

tgctttgagtaattcttcgattctgttctc	CRISPR spacer
aaatttgagtaattctccaattctgtaatc	Protospacer
 . *************.*.*******  **

30. spacer 6.11|601203|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028328 (Lactobacillus sp. D1501 plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.767

atttttaacgttctcaatgagtaatattga	CRISPR spacer
acttttaatgttctcaatgtgtaattgttg	Protospacer
*.******.********** *****  * .

31. spacer 6.12|601269|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to MN693722 (Marine virus AFVG_250M657, complete genome) position: , mismatch: 7, identity: 0.767

atctcctaaagcaacaatcacgcagctaga	CRISPR spacer
accacctaaagcaacaatcgcgctgctgcg	Protospacer
*.* ***************.*** ***. .

32. spacer 6.3|600675|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NC_019848 (Sinorhizobium meliloti GR4 plasmid pRmeGR4c, complete sequence) position: , mismatch: 8, identity: 0.733

ctagaactgctgacaaagcgacttttgaca	CRISPR spacer
ggcggccggctgccaaagcgacttttgacg	Protospacer
   *. * **** ****************.

33. spacer 6.3|600675|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NC_003037 (Sinorhizobium meliloti 1021 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.733

ctagaactgctgacaaagcgacttttgaca	CRISPR spacer
ggcggccggctgccaaagcgacttttgacg	Protospacer
   *. * **** ****************.

34. spacer 6.3|600675|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019585 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.733

ctagaactgctgacaaagcgacttttgaca	CRISPR spacer
ggcggccggctgccaaagcgacttttgacg	Protospacer
   *. * **** ****************.

35. spacer 6.3|600675|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013109 (Sinorhizobium americanum strain CFNEI 73 plasmid B, complete sequence) position: , mismatch: 8, identity: 0.733

ctagaactgctgacaaagcgacttttgaca	CRISPR spacer
ggcggccggctgccaaagcgacttttgacg	Protospacer
   *. * **** ****************.

36. spacer 6.3|600675|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NC_017327 (Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence) position: , mismatch: 8, identity: 0.733

ctagaactgctgacaaagcgacttttgaca	CRISPR spacer
ggcggccggctgccaaagcgacttttgacg	Protospacer
   *. * **** ****************.

37. spacer 6.3|600675|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021798 (Sinorhizobium meliloti strain USDA1106 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.733

ctagaactgctgacaaagcgacttttgaca	CRISPR spacer
ggcggccggctgccaaagcgacttttgacg	Protospacer
   *. * **** ****************.

38. spacer 6.3|600675|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NC_017324 (Sinorhizobium meliloti BL225C plasmid pSINMEB01, complete sequence) position: , mismatch: 8, identity: 0.733

ctagaactgctgacaaagcgacttttgaca	CRISPR spacer
ggcggccggctgccaaagcgacttttgacc	Protospacer
   *. * **** ****************

39. spacer 6.3|600675|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009145 (Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.733

ctagaactgctgacaaagcgacttttgaca	CRISPR spacer
ggcggccggctgccaaagcgacttttgacg	Protospacer
   *. * **** ****************.

40. spacer 6.3|600675|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021128 (Rhizobium sp. Kim5 plasmid pRetKim5d, complete sequence) position: , mismatch: 8, identity: 0.733

ctagaactgctgacaaagcgacttttgaca	CRISPR spacer
ggcggtctgctgccaaagcggcttttgacg	Protospacer
   *. ****** *******.********.

41. spacer 6.3|600675|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021801 (Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.733

ctagaactgctgacaaagcgacttttgaca	CRISPR spacer
ggcggccggctgccaaagcgacttttgacg	Protospacer
   *. * **** ****************.

42. spacer 6.3|600675|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013053 (Sinorhizobium americanum CCGM7 plasmid B, complete sequence) position: , mismatch: 8, identity: 0.733

ctagaactgctgacaaagcgacttttgaca	CRISPR spacer
ggcggccggctgccaaagcgacttttgacg	Protospacer
   *. * **** ****************.

43. spacer 6.3|600675|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021824 (Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.733

ctagaactgctgacaaagcgacttttgaca	CRISPR spacer
ggcggccggctgccaaagcgacttttgacg	Protospacer
   *. * **** ****************.

44. spacer 6.3|600675|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NC_018683 (Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence) position: , mismatch: 8, identity: 0.733

ctagaactgctgacaaagcgacttttgaca	CRISPR spacer
ggcggccggctgccaaagcgacttttgacg	Protospacer
   *. * **** ****************.

45. spacer 6.3|600675|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021794 (Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.733

ctagaactgctgacaaagcgacttttgaca	CRISPR spacer
ggcggccggctgccaaagcgacttttgacc	Protospacer
   *. * **** ****************

46. spacer 6.3|600675|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021809 (Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.733

ctagaactgctgacaaagcgacttttgaca	CRISPR spacer
ggcggccggctgccaaagcgacttttgacg	Protospacer
   *. * **** ****************.

47. spacer 6.3|600675|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021217 (Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.733

ctagaactgctgacaaagcgacttttgaca	CRISPR spacer
ggcggccggctgccaaagcgacttttgacg	Protospacer
   *. * **** ****************.

48. spacer 6.3|600675|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026526 (Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.733

ctagaactgctgacaaagcgacttttgaca	CRISPR spacer
ggcggccggctgccaaagcgacttttgacc	Protospacer
   *. * **** ****************

49. spacer 6.3|600675|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019486 (Sinorhizobium meliloti strain B399 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.733

ctagaactgctgacaaagcgacttttgaca	CRISPR spacer
ggcggccggctgccaaagcgacttttgacg	Protospacer
   *. * **** ****************.

50. spacer 6.3|600675|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NC_020527 (Sinorhizobium meliloti 2011 plasmid pSymA, complete sequence) position: , mismatch: 8, identity: 0.733

ctagaactgctgacaaagcgacttttgaca	CRISPR spacer
ggcggccggctgccaaagcgacttttgacg	Protospacer
   *. * **** ****************.

51. spacer 6.5|600807|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to KX077895 (Streptococcus phage phiZJ20091101-4, complete genome) position: , mismatch: 8, identity: 0.733

tgttctaaaaatacaagaggcaaccaagcg	CRISPR spacer
tttaaaaaaattacaagaggcaaccaatga	Protospacer
* *   **** ****************  .

52. spacer 6.9|601071|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to MG250483 (Aeromonas phage Ah1, complete genome) position: , mismatch: 8, identity: 0.733

aatgttaaacaagattgagagtcaagctac	CRISPR spacer
catgacaaacaagattgagagtcaaagcga	Protospacer
 *** .*******************. ..

53. spacer 6.5|600807|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to LR588166 (Pseudomonas phage vB_PaeM_MIJ3) position: , mismatch: 9, identity: 0.7

tgttctaaaaatacaagaggcaaccaagcg	CRISPR spacer
ctttctaaaaatataagaggcaaaaagtaa	Protospacer
. ***********.*********  *.  .

54. spacer 6.5|600807|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to MH121069 (Pseudomonas phage vB_PaeM_PA5oct, complete genome) position: , mismatch: 9, identity: 0.7

tgttctaaaaatacaagaggcaaccaagcg	CRISPR spacer
ctttctaaaaatataagaggcaaaaagtaa	Protospacer
. ***********.*********  *.  .

55. spacer 6.1|600543|30|NZ_CP019323|PILER-CR,CRISPRCasFinder,CRT matches to NC_048106 (Synechococcus phage S-CBWM1, complete genome) position: , mismatch: 10, identity: 0.667

aaaaaaattggtagttctttcacaggagca	CRISPR spacer
gggtgaattggcagttctttcacaggctgt	Protospacer
... .******.**************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

662417 : 669784

Enterococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_083686014.1\|662417_663011_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	2.3e-18	35.1
WP_076614115.1\|663143_664172_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	1.0e-119	65.5
WP_076614116.1\|664184_666350_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	1.7e-252	60.1
WP_076614117.1\|666336_666711_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A142F1R4	Bacillus_phage	5.5e-10	33.6
WP_076614118.1\|666710_666941_-	glutaredoxin-like protein NrdH	A0A0M7REK7	Lactobacillus_phage	1.7e-09	46.1
WP_076614119.1\|667225_667858_+	hypothetical protein	NA	NA	NA	NA
WP_076614120.1\|667991_668195_-	DUF2187 domain-containing protein	NA	NA	NA	NA
WP_076614121.1\|668279_668837_+	AAA family ATPase	A0A2R2ZH49	Clostridioides_phage	4.6e-13	35.3
WP_076614122.1\|669052_669784_+	C40 family peptidase	D2KRB9	Lactobacillus_phage	1.2e-13	42.9

DBSCAN-SWA_2

702791 : 708938

Lactobacillus_phage(50.0%)

transposase,bacteriocin,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076614152.1\|702791_703232_-\|transposase	IS200/IS605 family transposase	A0A0P0IQC6	Lactobacillus_phage	1.2e-37	58.9
WP_076614153.1\|703330_704593_+\|transposase	transposase	A0A288TXV8	Enterococcus_phage	1.9e-54	38.8
WP_076614154.1\|705399_705675_+	hypothetical protein	NA	NA	NA	NA
WP_076614155.1\|705806_706160_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_076614156.1\|706297_706591_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_076614157.1\|706696_706900_+	hypothetical protein	NA	NA	NA	NA
WP_076614158.1\|706912_707122_+	hypothetical protein	NA	NA	NA	NA
WP_076614159.1\|707149_707425_+	hypothetical protein	NA	NA	NA	NA
WP_076614160.1\|707567_708227_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_192844200.1\|708305_708938_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_3

1128464 : 1165513

Lactobacillus_phage(32.0%)

integrase,transposase,portal,tRNA,capsid,terminase

attL 1137495:1137510|attR 1157122:1157137

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_043023465.1\|1128464_1129490_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	5.7e-41	35.5
WP_076614535.1\|1129621_1130467_+	WxL domain-containing protein	NA	NA	NA	NA
WP_076614536.1\|1130595_1131690_+	DUF3324 domain-containing protein	NA	NA	NA	NA
WP_076614537.1\|1131786_1132767_+	DUF3324 domain-containing protein	NA	NA	NA	NA
WP_076614538.1\|1132771_1133806_+	DUF916 domain-containing protein	NA	NA	NA	NA
WP_076614539.1\|1133833_1135342_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_083685930.1\|1135688_1137137_+	amino acid permease	NA	NA	NA	NA
WP_076614541.1\|1137420_1138710_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.0e-92	43.9
1137495:1137510	attL	NA	NA	NA	NA
WP_076614542.1\|1139205_1140321_-\|integrase	site-specific integrase	E3W8I1	Leuconostoc_phage	3.3e-42	32.1
WP_076614543.1\|1140482_1141190_-	hypothetical protein	A0A059T7Z1	Listeria_phage	3.6e-18	34.2
WP_076614544.1\|1141251_1141953_-	helix-turn-helix domain-containing protein	E5DV74	Deep-sea_thermophilic_phage	9.9e-21	38.0
WP_076614545.1\|1142094_1142328_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_125673057.1\|1142507_1142906_+	hypothetical protein	NA	NA	NA	NA
WP_076614547.1\|1142892_1143228_+	DUF771 domain-containing protein	NA	NA	NA	NA
WP_076614548.1\|1143229_1143508_+	hypothetical protein	NA	NA	NA	NA
WP_076614549.1\|1143906_1144449_+	host-nuclease inhibitor Gam family protein	A0A0H3U480	Staphylococcus_phage	2.2e-20	31.8
WP_076614550.1\|1144451_1145201_+	ERF family protein	Q9G0C9	Lactococcus_phage	5.4e-25	46.4
WP_076614551.1\|1145230_1146025_+	DnaD domain protein	A0A1L2JY26	Aeribacillus_phage	1.3e-24	34.8
WP_076614552.1\|1146037_1146805_+	ATP-binding protein	O03914	Lactobacillus_phage	1.2e-19	36.1
WP_076614553.1\|1146807_1147095_+	hypothetical protein	NA	NA	NA	NA
WP_076614554.1\|1147109_1147391_+	hypothetical protein	NA	NA	NA	NA
WP_076614555.1\|1147391_1147835_+	RusA family crossover junction endodeoxyribonuclease	A8YQM5	Lactobacillus_phage	1.1e-17	39.7
WP_164510783.1\|1147860_1148043_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_076614557.1\|1148219_1148984_+	phage antirepressor KilAC domain-containing protein	B8R674	Lactobacillus_phage	5.3e-68	52.6
WP_076614558.1\|1148980_1149448_+	single-stranded DNA-binding protein	C5IUI2	Streptococcus_phage	5.9e-38	58.3
WP_076614559.1\|1149461_1150214_+	site-specific DNA-methyltransferase	B4XYT3	Lactobacillus_phage	6.7e-108	74.6
WP_076614560.1\|1150228_1150438_+	hypothetical protein	NA	NA	NA	NA
WP_076614561.1\|1150453_1150672_+	hypothetical protein	NA	NA	NA	NA
WP_076614562.1\|1150668_1151796_+	DNA cytosine methyltransferase	A0A1I9KKE7	Lactobacillus_phage	1.1e-109	56.1
WP_076614563.1\|1151809_1152232_+	hypothetical protein	NA	NA	NA	NA
WP_157886442.1\|1152221_1152383_+	hypothetical protein	NA	NA	NA	NA
WP_076614564.1\|1152467_1152875_+	hypothetical protein	NA	NA	NA	NA
WP_076614565.1\|1152998_1153424_+	hypothetical protein	D2IZ85	Enterococcus_phage	2.4e-06	27.9
WP_076614566.1\|1153928_1154189_+	hypothetical protein	A0A0A7AR29	Bacillus_phage	2.9e-18	49.4
WP_076614567.1\|1154188_1154392_+	hypothetical protein	NA	NA	NA	NA
WP_076614568.1\|1154431_1154662_+	hypothetical protein	NA	NA	NA	NA
WP_125673045.1\|1154664_1154847_+	hypothetical protein	NA	NA	NA	NA
WP_125673046.1\|1154806_1155121_+	hypothetical protein	NA	NA	NA	NA
WP_083686019.1\|1155132_1155696_+	ParB N-terminal domain-containing protein	X2CXX2	Lactobacillus_phage	1.6e-37	65.0
WP_076614571.1\|1155692_1156460_+	hypothetical protein	NA	NA	NA	NA
WP_076614572.1\|1156471_1157188_+	queuosine precursor transporter	A0A1W7AG82	Streptococcus_virus	1.5e-32	37.0
1157122:1157137	attR	NA	NA	NA	NA
WP_076614573.1\|1157200_1157902_+	7-cyano-7-deazaguanine synthase QueC	A0A1U9WRB5	Streptococcus_virus	5.9e-66	53.1
WP_076614574.1\|1157941_1158595_+	helix-turn-helix domain-containing protein	A0A1S5SAA7	Streptococcus_phage	6.8e-40	52.8
WP_076614575.1\|1158578_1159898_+\|terminase	PBSX family phage terminase large subunit	M1PG09	Streptococcus_phage	1.7e-122	52.7
WP_076614576.1\|1159916_1161527_+\|portal	phage portal protein	D2IZF6	Enterococcus_phage	4.8e-71	34.8
WP_076614577.1\|1161507_1161867_+	hypothetical protein	NA	NA	NA	NA
WP_076614578.1\|1161853_1162843_+\|capsid	minor capsid protein	A0A2P1JTW9	Anoxybacillus_phage	9.7e-06	32.5
WP_076614579.1\|1162837_1163335_-	hypothetical protein	NA	NA	NA	NA
WP_076614580.1\|1163497_1164157_+	DUF4355 domain-containing protein	NA	NA	NA	NA
WP_076614581.1\|1164169_1164496_+	hypothetical protein	A0A0P0IJQ8	Lactobacillus_phage	3.0e-28	64.4
WP_076614582.1\|1164499_1165513_+\|capsid	major capsid protein	A0A0P0IZJ7	Lactobacillus_phage	2.3e-95	53.4

DBSCAN-SWA_4

1612436 : 1689068

Lactobacillus_phage(44.12%)

integrase,protease,capsid,portal,tail,tRNA,head,terminase,plate

attL 1603680:1603695|attR 1653250:1653265

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1603680:1603695	attL	NA	NA	NA	NA
WP_076615740.1\|1612436_1613612_-\|integrase	site-specific integrase	A0A2P0ZL94	Lactobacillus_phage	8.4e-57	37.0
WP_076615743.1\|1613729_1614806_-	hypothetical protein	NA	NA	NA	NA
WP_076615746.1\|1614870_1615269_-	hypothetical protein	D6PSS8	Lactobacillus_phage	4.2e-16	37.0
WP_076615749.1\|1615272_1615605_-	helix-turn-helix transcriptional regulator	A0A1B0Y3N1	Lactobacillus_phage	1.3e-10	35.5
WP_076615752.1\|1616016_1616220_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_076615755.1\|1616238_1617021_+	phage antirepressor KilAC domain-containing protein	A0A2H4JCR9	uncultured_Caudovirales_phage	7.8e-83	61.1
WP_157886445.1\|1617024_1617186_+	hypothetical protein	NA	NA	NA	NA
WP_157886446.1\|1617177_1617336_-	hypothetical protein	NA	NA	NA	NA
WP_076615759.1\|1617400_1617661_+	DNA-binding protein	NA	NA	NA	NA
WP_076615762.1\|1617918_1618554_-	hypothetical protein	E3W8C3	Leuconostoc_phage	5.3e-05	27.8
WP_125673037.1\|1618699_1618957_+	hypothetical protein	NA	NA	NA	NA
WP_076615770.1\|1618969_1619185_+	hypothetical protein	NA	NA	NA	NA
WP_076615774.1\|1619185_1619665_+	siphovirus Gp157 family protein	A6M981	Geobacillus_virus	3.8e-24	43.9
WP_083685954.1\|1619636_1620173_+	HNH endonuclease	A0A1W6JIP2	Lactococcus_phage	2.8e-31	45.1
WP_076615778.1\|1620295_1621549_+	DEAD/DEAH box helicase	A0A0A1ENT0	Lactobacillus_phage	1.6e-154	64.3
WP_076615781.1\|1621545_1621791_+	hypothetical protein	NA	NA	NA	NA
WP_076615784.1\|1621790_1622558_+	AAA family ATPase	A0A1B0YEB5	Lactobacillus_phage	2.1e-85	64.3
WP_076615787.1\|1622560_1623124_+	DUF669 domain-containing protein	A0A1B0Y6E2	Lactobacillus_phage	1.1e-33	41.4
WP_076615790.1\|1623190_1623988_+	bifunctional DNA primase/polymerase	A0A2P0ZLB0	Lactobacillus_phage	3.1e-79	57.6
WP_076615794.1\|1623984_1625244_+	helicase	A0A0A1EL11	Lactobacillus_phage	1.2e-128	56.0
WP_076615797.1\|1625525_1625861_+	VRR-NUC domain-containing protein	A0A2P0ZLB6	Lactobacillus_phage	7.7e-40	70.9
WP_076615800.1\|1625847_1626039_+	hypothetical protein	NA	NA	NA	NA
WP_076615803.1\|1626101_1626533_+	hypothetical protein	NA	NA	NA	NA
WP_076615806.1\|1626603_1627014_+	hypothetical protein	NA	NA	NA	NA
WP_076615808.1\|1627013_1627430_+	hypothetical protein	NA	NA	NA	NA
WP_076615811.1\|1627432_1627633_+	hypothetical protein	NA	NA	NA	NA
WP_076615814.1\|1627721_1628141_+	hypothetical protein	NA	NA	NA	NA
WP_076615816.1\|1628950_1629160_+	hypothetical protein	NA	NA	NA	NA
WP_056950744.1\|1629174_1629552_+	hypothetical protein	NA	NA	NA	NA
WP_076618830.1\|1629538_1630051_+	HNH endonuclease	A0A2I6QQZ5	Streptococcus_phage	1.6e-23	40.1
WP_076615819.1\|1630147_1630639_+\|terminase	phage terminase small subunit P27 family	E3W8E9	Leuconostoc_phage	4.2e-10	33.7
WP_083685957.1\|1630639_1632514_+\|terminase	terminase large subunit	A0A286QQH3	Streptococcus_phage	6.7e-165	49.9
WP_054642048.1\|1632526_1632721_+	hypothetical protein	NA	NA	NA	NA
WP_076615820.1\|1632749_1633955_+\|portal	phage portal protein	E9LUQ1	Lactobacillus_phage	9.2e-67	37.8
WP_076615822.1\|1633917_1634523_+\|head,protease	HK97 family phage prohead protease	B8R651	Lactobacillus_phage	1.1e-33	43.7
WP_057892382.1\|1634512_1635739_+\|capsid	phage major capsid protein	B4XYP6	Lactobacillus_phage	9.7e-80	43.9
WP_076615824.1\|1635741_1636098_+\|head,tail	phage gp6-like head-tail connector protein	F8HGT2	Streptococcus_phage	1.5e-09	41.1
WP_076615827.1\|1636072_1636426_+\|head,tail	head-tail adaptor protein	F8J1B7	Lactobacillus_phage	1.1e-09	32.2
WP_164510768.1\|1636490_1636847_+	hypothetical protein	NA	NA	NA	NA
WP_076615832.1\|1636848_1637214_+	DUF806 family protein	NA	NA	NA	NA
WP_076615835.1\|1637214_1637853_+	hypothetical protein	NA	NA	NA	NA
WP_076615837.1\|1637870_1638284_+	hypothetical protein	NA	NA	NA	NA
WP_156314048.1\|1638331_1638508_+	hypothetical protein	NA	NA	NA	NA
WP_076615839.1\|1638511_1643839_+\|tail	phage tail tape measure protein	Q9AZS0	Lactococcus_phage	1.0e-117	40.8
WP_076615841.1\|1643831_1644689_+\|tail	phage tail family protein	NA	NA	NA	NA
WP_076615843.1\|1644685_1646014_+\|tail	phage tail protein	A0A059T5E5	Listeria_phage	4.2e-20	30.6
WP_076615846.1\|1646006_1646930_+\|tail	phage tail protein	A0A0M7RDS2	Lactobacillus_phage	2.9e-12	31.6
WP_076615848.1\|1646926_1647265_+	hypothetical protein	NA	NA	NA	NA
WP_076615851.1\|1647269_1647830_+	hypothetical protein	NA	NA	NA	NA
WP_076615853.1\|1647845_1648625_+\|plate	BppU family phage baseplate upper protein	NA	NA	NA	NA
WP_076615856.1\|1648624_1649842_+	hypothetical protein	NA	NA	NA	NA
WP_076615859.1\|1649854_1650334_+	hypothetical protein	NA	NA	NA	NA
WP_076615862.1\|1650359_1650641_+	hypothetical protein	NA	NA	NA	NA
WP_083685959.1\|1650706_1650847_+	XkdX family protein	NA	NA	NA	NA
WP_076615865.1\|1650897_1651200_+	hypothetical protein	NA	NA	NA	NA
WP_076615868.1\|1651196_1651409_+	hypothetical protein	NA	NA	NA	NA
WP_076615871.1\|1651408_1652449_+	hypothetical protein	A0A1U9WQS3	Geobacillus_phage	1.1e-10	31.9
WP_076615874.1\|1652551_1652812_+	hypothetical protein	NA	NA	NA	NA
WP_076615877.1\|1652874_1653576_+	Fic family protein	NA	NA	NA	NA
1653250:1653265	attR	NA	NA	NA	NA
WP_076615880.1\|1653844_1654219_+	hypothetical protein	NA	NA	NA	NA
WP_076615882.1\|1654230_1654410_+	hypothetical protein	O48431	Lactobacillus_phage	1.9e-08	53.4
WP_192844188.1\|1654505_1654724_+	hypothetical protein	NA	NA	NA	NA
WP_076615886.1\|1655352_1655826_+	hypothetical protein	NA	NA	NA	NA
WP_025024889.1\|1656069_1656270_+	cold-shock protein	Q9AZD3	Lactococcus_phage	2.5e-22	75.4
WP_076615889.1\|1656658_1657888_+	arginine deiminase	NA	NA	NA	NA
WP_076615892.1\|1657915_1658953_+	ornithine carbamoyltransferase	NA	NA	NA	NA
WP_076615895.1\|1658975_1659917_+	carbamate kinase	NA	NA	NA	NA
WP_076615898.1\|1660171_1661866_+\|tRNA	arginine--tRNA ligase	A0A2I2L3K1	Orpheovirus	9.9e-83	33.5
WP_125673038.1\|1661910_1662798_+	prenyltransferase	NA	NA	NA	NA
WP_076615904.1\|1662961_1663852_-	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_076615907.1\|1663940_1666022_+	PBP1A family penicillin-binding protein	NA	NA	NA	NA
WP_076615910.1\|1666031_1666373_+	YlbF family regulator	NA	NA	NA	NA
WP_076615913.1\|1666453_1667614_+	DNA repair exonuclease	NA	NA	NA	NA
WP_076615916.1\|1667616_1670064_+	AAA family ATPase	NA	NA	NA	NA
WP_076615918.1\|1670063_1670999_+	HD domain-containing protein	NA	NA	NA	NA
WP_083685961.1\|1671061_1671961_-	peptidylprolyl isomerase	NA	NA	NA	NA
WP_076615920.1\|1672063_1672363_-	hypothetical protein	NA	NA	NA	NA
WP_076615923.1\|1672364_1672793_-	HIT family protein	D7NW73	Streptomyces_phage	1.2e-08	31.3
WP_076615925.1\|1672880_1673612_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.2e-22	28.8
WP_076615928.1\|1673611_1674838_+	ABC transporter permease	NA	NA	NA	NA
WP_076615930.1\|1674843_1675488_+\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_076615932.1\|1675499_1675814_-	hypothetical protein	NA	NA	NA	NA
WP_076615933.1\|1675946_1676273_+	thioredoxin family protein	NA	NA	NA	NA
WP_076615936.1\|1676290_1676923_+\|tRNA	DUF4479 and tRNA-binding domain-containing protein	NA	NA	NA	NA
WP_076615938.1\|1676931_1678266_+	UDP-N-acetylmuramate--L-alanine ligase	NA	NA	NA	NA
WP_076615942.1\|1678362_1679766_+	MFS transporter	NA	NA	NA	NA
WP_076615945.1\|1679914_1682572_+	DNA polymerase I	A0A068EMS7	Bacillus_phage	1.2e-50	27.0
WP_076615949.1\|1682604_1683432_+	DNA-formamidopyrimidine glycosylase	F8WPX6	Bacillus_phage	4.7e-30	30.3
WP_076615952.1\|1683428_1684022_+	dephospho-CoA kinase	NA	NA	NA	NA
WP_076615955.1\|1684043_1684529_+	transcriptional repressor NrdR	NA	NA	NA	NA
WP_076615958.1\|1684540_1685923_+	DnaD domain protein	NA	NA	NA	NA
WP_076615961.1\|1685925_1686831_+	primosomal protein DnaI	S5MU12	Brevibacillus_phage	1.8e-30	40.7
WP_076615963.1\|1687121_1689068_+\|tRNA	threonine--tRNA ligase	A0A1V0SKZ9	Klosneuvirus	7.4e-66	35.6

DBSCAN-SWA_5

1758723 : 1767209

Cyanophage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076616174.1\|1758723_1759209_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.0e-20	42.4
WP_120270384.1\|1759171_1760323_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_076616182.1\|1760332_1761037_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A1D7SPE1	Cyanophage	1.2e-39	37.3
WP_076616184.1\|1761046_1761295_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_076616187.1\|1761294_1761972_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_076616190.1\|1761972_1764180_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	3.1e-145	39.4
WP_076616192.1\|1764164_1765574_+	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	7.0e-50	30.5
WP_076616195.1\|1765584_1766613_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7STB2	Cyanophage	2.6e-70	46.3
WP_076616198.1\|1766609_1767209_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.5e-30	41.0

DBSCAN-SWA_6

1814139 : 1873061

Lactobacillus_phage(53.49%)

integrase,portal,tail,tRNA,capsid,terminase,plate

attL 1823103:1823119|attR 1866782:1866798

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076616323.1\|1814139_1815135_+\|tRNA	tRNA-dihydrouridine synthase family protein	NA	NA	NA	NA
WP_076616324.1\|1815180_1815429_-	hypothetical protein	NA	NA	NA	NA
WP_076616327.1\|1815425_1815971_-	NTP transferase domain-containing protein	NA	NA	NA	NA
WP_076616330.1\|1815960_1816449_-	molybdopterin-guanine dinucleotide biosynthesis protein MobB	NA	NA	NA	NA
WP_076616332.1\|1816427_1817657_-	molybdopterin molybdotransferase MoeA	NA	NA	NA	NA
WP_076616335.1\|1817656_1818124_-	molybdenum cofactor biosynthesis protein MoaB	NA	NA	NA	NA
WP_076616337.1\|1818123_1818855_-	HesA/MoeB/ThiF family protein	A0A1V0SCZ9	Indivirus	4.5e-08	27.9
WP_076616340.1\|1818965_1822619_+	nitrate reductase subunit alpha	NA	NA	NA	NA
WP_076616343.1\|1822608_1824168_+	nitrate reductase subunit beta	A0A077SL61	Escherichia_phage	8.4e-20	45.5
1823103:1823119	attL	NA	NA	NA	NA
WP_076616346.1\|1824160_1824745_+	nitrate reductase molybdenum cofactor assembly chaperone	NA	NA	NA	NA
WP_076616349.1\|1824741_1825434_+	respiratory nitrate reductase subunit gamma	NA	NA	NA	NA
WP_083685966.1\|1825454_1826447_+	iron ABC transporter permease	NA	NA	NA	NA
WP_076616356.1\|1826433_1827216_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	3.1e-15	25.7
WP_076616359.1\|1827218_1828253_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_076616362.1\|1828249_1828657_+	molybdenum cofactor biosynthesis protein MoaE	NA	NA	NA	NA
WP_083685967.1\|1828653_1828893_+	MoaD/ThiS family protein	NA	NA	NA	NA
WP_076616365.1\|1828911_1830087_+	NarK/NasA family nitrate transporter	NA	NA	NA	NA
WP_076616368.1\|1830107_1830431_+	metal-sulfur cluster assembly factor	NA	NA	NA	NA
WP_076616371.1\|1830658_1832005_+	NADP-specific glutamate dehydrogenase	NA	NA	NA	NA
WP_076616375.1\|1832102_1832963_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	5.4e-61	43.8
WP_076616378.1\|1833117_1834257_-	AI-2E family transporter	NA	NA	NA	NA
WP_076616381.1\|1834373_1835363_-	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	1.8e-52	38.5
WP_076616384.1\|1835517_1836180_+	class A sortase	NA	NA	NA	NA
WP_076616387.1\|1836245_1838552_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	3.4e-78	31.1
WP_076616390.1\|1838573_1839092_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	9.9e-26	44.4
WP_076616394.1\|1839339_1840461_-\|integrase	site-specific integrase	E9LUS1	Lactobacillus_phage	2.3e-104	54.0
WP_076616397.1\|1840602_1841454_-	SHOCT domain-containing protein	O48432	Lactobacillus_phage	1.9e-21	28.5
WP_083685968.1\|1841510_1841939_-	ImmA/IrrE family metallo-endopeptidase	A0A1B0Y2S4	Lactobacillus_phage	5.3e-25	41.8
WP_076616400.1\|1841941_1842895_-\|capsid	minor capsid protein	NA	NA	NA	NA
WP_076616403.1\|1842884_1843229_-	helix-turn-helix domain-containing protein	A0A1B0Y3N1	Lactobacillus_phage	1.0e-10	39.1
WP_076616406.1\|1843486_1843696_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_076616408.1\|1843706_1844495_+	phage antirepressor KilAC domain-containing protein	A0A1Q1PVU2	Staphylococcus_phage	2.3e-74	53.3
WP_076616411.1\|1844498_1844831_+	DUF771 domain-containing protein	E9LUT3	Lactobacillus_phage	9.1e-25	46.8
WP_157886447.1\|1844824_1844998_+	hypothetical protein	NA	NA	NA	NA
WP_076616414.1\|1845137_1845644_-	hypothetical protein	NA	NA	NA	NA
WP_076616420.1\|1845931_1846843_+	DUF1351 domain-containing protein	V9QIX7	Oenococcus_phage	3.2e-27	28.9
WP_076616424.1\|1846839_1847484_+	ERF family protein	NA	NA	NA	NA
WP_083685969.1\|1847495_1848152_+	hypothetical protein	A0A2D1GP81	Lactobacillus_phage	1.0e-59	49.8
WP_076616426.1\|1848154_1848883_+	helix-turn-helix domain-containing protein	A0A2I6PDW4	Staphylococcus_phage	6.9e-25	60.6
WP_076616428.1\|1848898_1849669_+	ATP-binding protein	E9LUM7	Lactobacillus_phage	1.7e-18	30.2
WP_076616431.1\|1849671_1849947_+	hypothetical protein	NA	NA	NA	NA
WP_076616433.1\|1849936_1850479_+	single-stranded DNA-binding protein	A0A218MNB4	uncultured_virus	4.2e-35	68.2
WP_076616435.1\|1850496_1850937_+	replication terminator protein	M1I9V9	Streptococcus_phage	4.7e-29	53.6
WP_076616438.1\|1850950_1851136_+	hypothetical protein	NA	NA	NA	NA
WP_076616442.1\|1851147_1851363_+	hypothetical protein	NA	NA	NA	NA
WP_076616445.1\|1851355_1851574_+	hypothetical protein	NA	NA	NA	NA
WP_076616450.1\|1851603_1852023_+	hypothetical protein	E9LUP5	Lactobacillus_phage	2.2e-31	48.2
WP_076616454.1\|1852221_1852899_+	hypothetical protein	NA	NA	NA	NA
WP_076616457.1\|1852926_1853709_+\|terminase	terminase small subunit	V5URT8	Oenococcus_phage	6.0e-59	47.8
WP_083685970.1\|1853692_1854949_+\|terminase	terminase	B6CXD2	Clostridium_phage	7.1e-102	47.3
WP_076616464.1\|1854939_1856352_+\|portal	phage portal protein	X2CY64	Lactobacillus_phage	1.6e-150	54.8
WP_076616466.1\|1856338_1858375_+\|capsid	minor capsid protein	Q20DD6	Lactobacillus_phage	6.1e-87	45.9
WP_164510771.1\|1858367_1858526_+	hypothetical protein	NA	NA	NA	NA
WP_076616469.1\|1858653_1859205_+	phage scaffolding protein	X2CYF9	Lactobacillus_phage	2.2e-39	50.3
WP_076616471.1\|1859220_1860135_+\|capsid	capsid protein	Q20DD4	Lactobacillus_phage	2.9e-129	77.0
WP_076616474.1\|1860210_1860666_+	Ig domain-containing protein	A6MAC0	Lactococcus_virus	3.1e-07	50.6
WP_076616476.1\|1860675_1861065_+	hypothetical protein	X2CXX4	Lactobacillus_phage	1.4e-29	47.2
WP_076618867.1\|1861082_1861439_+	hypothetical protein	A9D9T8	Lactobacillus_prophage	3.3e-41	74.5
WP_076616479.1\|1861439_1861862_+	HK97 gp10 family phage protein	A0A0A8WFV8	Clostridium_phage	1.7e-12	34.0
WP_076616482.1\|1861858_1862266_+	hypothetical protein	X2CYG1	Lactobacillus_phage	2.1e-23	39.4
WP_157886448.1\|1862255_1862411_+	hypothetical protein	X2CY66	Lactobacillus_phage	2.8e-05	50.0
WP_076616485.1\|1862410_1863829_+\|tail	phage tail sheath subtilisin-like domain-containing protein	X2CXX5	Lactobacillus_phage	6.9e-122	51.2
WP_076616488.1\|1863844_1864330_+\|tail	phage tail tube protein	Q20DC7	Lactobacillus_phage	4.7e-62	73.5
WP_076616491.1\|1864372_1864762_+	hypothetical protein	Q20DC6	Lactobacillus_phage	9.7e-26	48.8
WP_164510772.1\|1864806_1864956_+	hypothetical protein	NA	NA	NA	NA
WP_076616494.1\|1864992_1868112_+	tape measure protein	X2CYG3	Lactobacillus_phage	3.5e-102	48.0
1866782:1866798	attR	NA	NA	NA	NA
WP_076616498.1\|1868122_1868809_+	hypothetical protein	A9D9W2	Lactobacillus_prophage	1.7e-49	47.6
WP_076616501.1\|1868805_1869858_+	hypothetical protein	A9D9W5	Lactobacillus_prophage	5.4e-71	41.9
WP_076616504.1\|1869830_1870199_+	DUF2577 domain-containing protein	L0P6Y6	Lactobacillus_phage	1.8e-21	50.4
WP_120270389.1\|1870185_1870551_+	DUF2634 domain-containing protein	A9D9X1	Lactobacillus_prophage	2.5e-31	62.8
WP_076616509.1\|1870540_1871689_+\|plate	baseplate J/gp47 family protein	X2CYG4	Lactobacillus_phage	2.7e-132	58.8
WP_076616512.1\|1871681_1872476_+	DUF2313 domain-containing protein	Q20DB9	Lactobacillus_phage	2.3e-37	47.2
WP_076616515.1\|1872476_1873061_+\|tail	phage tail protein	Q20DB8	Lactobacillus_phage	2.8e-29	42.9

DBSCAN-SWA_7

2002685 : 2050160

Lactobacillus_phage(36.36%)

integrase,portal,tail,capsid,terminase,plate

attL 1996721:1996737|attR 2008041:2008057

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1996721:1996737	attL	NA	NA	NA	NA
WP_076616896.1\|2002685_2003525_+\|integrase	phage integrase N-terminal SAM-like domain-containing protein	NA	NA	NA	NA
WP_076618890.1\|2003526_2004093_+	TIGR00730 family Rossman fold protein	NA	NA	NA	NA
WP_125673040.1\|2004361_2004727_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_076616903.1\|2004728_2005169_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_076616907.1\|2005435_2006329_-	ribose uptake protein RbsU	NA	NA	NA	NA
WP_076616911.1\|2006511_2007447_-	manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
WP_076616915.1\|2007469_2008429_-	LysR family transcriptional regulator	NA	NA	NA	NA
2008041:2008057	attR	NA	NA	NA	NA
WP_120270393.1\|2008520_2010962_-	DNA topoisomerase IV subunit A	A0A172JHV7	Bacillus_phage	2.9e-99	30.7
WP_076616922.1\|2010972_2012973_-	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	1.2e-119	41.5
WP_076616925.1\|2013193_2013811_+	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_076616929.1\|2013996_2015016_-	hypothetical protein	U3PJ04	Lactobacillus_phage	5.5e-28	37.1
WP_076616933.1\|2015017_2015380_-	hypothetical protein	O03941	Lactobacillus_phage	6.1e-06	43.5
WP_076616937.1\|2015379_2015694_-	hypothetical protein	NA	NA	NA	NA
WP_076616942.1\|2015690_2016074_-	hypothetical protein	NA	NA	NA	NA
WP_120270396.1\|2016111_2016243_-	XkdX family protein	NA	NA	NA	NA
WP_076616946.1\|2016255_2016693_-	hypothetical protein	NA	NA	NA	NA
WP_076616950.1\|2016692_2017910_-	hypothetical protein	NA	NA	NA	NA
WP_076616953.1\|2017912_2018188_-	hypothetical protein	NA	NA	NA	NA
WP_076616956.1\|2018187_2019216_-\|plate	BppU family phage baseplate upper protein	NA	NA	NA	NA
WP_076616959.1\|2019219_2019900_-	hypothetical protein	NA	NA	NA	NA
WP_076616963.1\|2019911_2022101_-\|tail	phage tail protein	O03938	Lactobacillus_phage	1.3e-34	38.0
WP_076616966.1\|2022109_2022925_-\|tail	phage tail family protein	A6M962	Geobacillus_virus	2.3e-29	32.1
WP_076616970.1\|2022924_2026947_-	hypothetical protein	A0A0A7DMV4	Lactobacillus_phage	1.4e-42	53.3
WP_076616973.1\|2026906_2029066_-\|tail	phage tail tape measure protein	B4XYQ3	Lactobacillus_phage	2.4e-110	52.0
WP_076616976.1\|2029099_2029756_-	hypothetical protein	A5GYM7	Lactococcus_phage	1.0e-11	26.8
WP_076616979.1\|2029697_2030261_-	hypothetical protein	NA	NA	NA	NA
WP_076616982.1\|2030329_2030608_-	hypothetical protein	NA	NA	NA	NA
WP_076616985.1\|2030622_2031432_-	hypothetical protein	NA	NA	NA	NA
WP_076616988.1\|2031445_2031895_-	hypothetical protein	NA	NA	NA	NA
WP_076616991.1\|2031875_2032238_-	hypothetical protein	NA	NA	NA	NA
WP_076616995.1\|2032234_2032600_-	hypothetical protein	NA	NA	NA	NA
WP_076616998.1\|2032596_2032998_-	hypothetical protein	NA	NA	NA	NA
WP_076617001.1\|2033014_2033965_-\|capsid	N4-gp56 family major capsid protein	A8ASJ6	Listeria_phage	6.1e-82	55.7
WP_076617004.1\|2033976_2034561_-	hypothetical protein	NA	NA	NA	NA
WP_076617007.1\|2034646_2035141_+	hypothetical protein	NA	NA	NA	NA
WP_076617010.1\|2035145_2036243_-	hypothetical protein	A0A1B1P858	Bacillus_phage	1.4e-29	32.9
WP_157886449.1\|2036232_2037753_-\|portal	phage portal protein	B5LPR1	Bacillus_virus	1.8e-88	38.9
WP_076617016.1\|2037802_2039116_-\|terminase	PBSX family phage terminase large subunit	A0A1S5SA45	Streptococcus_phage	1.0e-135	53.7
WP_076617019.1\|2039099_2039945_-	hypothetical protein	D2J000	Enterococcus_phage	1.9e-42	41.1
WP_157886450.1\|2040526_2040952_-	autolysin	D2IZZ3	Enterococcus_phage	6.6e-20	39.9
WP_076617024.1\|2040992_2041448_-	hypothetical protein	NA	NA	NA	NA
WP_076617026.1\|2041588_2041771_-	hypothetical protein	NA	NA	NA	NA
WP_076617029.1\|2041773_2042010_-	hypothetical protein	NA	NA	NA	NA
WP_076617032.1\|2042006_2042291_-	hypothetical protein	NA	NA	NA	NA
WP_076617035.1\|2042277_2042487_-	hypothetical protein	NA	NA	NA	NA
WP_076617039.1\|2042505_2043072_-	single-stranded DNA-binding protein	A0A218MNB4	uncultured_virus	1.9e-38	68.8
WP_076617043.1\|2043172_2043910_-	phage antirepressor KilAC domain-containing protein	B4XYR8	Lactobacillus_phage	2.5e-62	54.5
WP_120270465.1\|2043902_2044586_-	conserved phage C-terminal domain-containing protein	X2CYF1	Lactobacillus_phage	2.6e-18	33.9
WP_076617049.1\|2044766_2045450_-	ERF family protein	Q8SDH6	Lactococcus_phage	1.9e-08	35.4
WP_076617053.1\|2045490_2045706_-	hypothetical protein	NA	NA	NA	NA
WP_076617056.1\|2045707_2045890_-	hypothetical protein	NA	NA	NA	NA
WP_076617059.1\|2045904_2046144_-	DNA-binding protein	NA	NA	NA	NA
WP_076617063.1\|2046149_2046644_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_076617067.1\|2046906_2047149_-	helix-turn-helix transcriptional regulator	A8ASM3	Listeria_phage	9.3e-11	55.4
WP_076617070.1\|2047299_2047674_+	helix-turn-helix transcriptional regulator	O03970	Lactobacillus_phage	3.5e-25	48.8
WP_076617073.1\|2047678_2048095_+	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_076617076.1\|2048151_2048580_+	hypothetical protein	NA	NA	NA	NA
WP_076617079.1\|2048612_2049092_+	DUF5067 domain-containing protein	NA	NA	NA	NA
WP_076617082.1\|2049152_2050160_+	hypothetical protein	A0A097BY73	Enterococcus_phage	7.8e-11	59.6

DBSCAN-SWA_8

2250386 : 2321967

Lactobacillus_phage(43.24%)

integrase,protease,capsid,portal,tail,tRNA,head,terminase

attL 2250789:2250803|attR 2322595:2322609

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076617702.1\|2250386_2253035_-\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	2.1e-164	44.0
2250789:2250803	attL	NA	NA	NA	NA
WP_076617706.1\|2253323_2254541_-\|tRNA	tRNA 4-thiouridine(8) synthase ThiI	NA	NA	NA	NA
WP_076617710.1\|2254565_2255711_-	cysteine desulfurase	A0A1X7C038	Faustovirus	1.8e-32	28.5
WP_076617713.1\|2255789_2257478_-	selenide, water dikinase	NA	NA	NA	NA
WP_076617717.1\|2257799_2258408_+	30S ribosomal protein S4	NA	NA	NA	NA
WP_076617720.1\|2258474_2259077_-	DUF1054 family protein	NA	NA	NA	NA
WP_076617724.1\|2259179_2260481_+	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	1.2e-99	49.0
WP_076617727.1\|2260470_2260752_+	hypothetical protein	NA	NA	NA	NA
WP_076617732.1\|2260821_2261301_+	universal stress protein	NA	NA	NA	NA
WP_076617736.1\|2261376_2262240_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_076617741.1\|2262341_2262635_-	glycine cleavage system protein H	NA	NA	NA	NA
WP_076617744.1\|2262647_2263850_-	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_076617748.1\|2263861_2264083_-	DUF2969 domain-containing protein	NA	NA	NA	NA
WP_120270411.1\|2264092_2264374_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.7e-17	53.1
WP_120270413.1\|2264392_2264575_-	DNA-directed RNA polymerase subunit beta	NA	NA	NA	NA
WP_076617752.1\|2264583_2265573_-	rod shape-determining protein	NA	NA	NA	NA
WP_076617756.1\|2265681_2267004_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_076617760.1\|2267032_2267263_-	DUF1146 domain-containing protein	NA	NA	NA	NA
WP_076617765.1\|2267457_2267889_-	F0F1 ATP synthase subunit epsilon	NA	NA	NA	NA
WP_076617768.1\|2267904_2269359_-	F0F1 ATP synthase subunit beta	NA	NA	NA	NA
WP_076617772.1\|2269379_2270297_-	F0F1 ATP synthase subunit gamma	NA	NA	NA	NA
WP_076617775.1\|2270314_2271841_-	F0F1 ATP synthase subunit alpha	NA	NA	NA	NA
WP_076617779.1\|2271857_2272406_-	F0F1 ATP synthase subunit delta	NA	NA	NA	NA
WP_076617782.1\|2272392_2272917_-	F0F1 ATP synthase subunit B	NA	NA	NA	NA
WP_076617787.1\|2272990_2273203_-	F0F1 ATP synthase subunit C	NA	NA	NA	NA
WP_076617791.1\|2273227_2273938_-	F0F1 ATP synthase subunit A	NA	NA	NA	NA
WP_076617794.1\|2274027_2274657_-	uracil phosphoribosyltransferase	NA	NA	NA	NA
WP_076617798.1\|2274712_2275723_-	threonylcarbamoyl-AMP synthase	A0A291ATS8	Pandoravirus	5.9e-59	40.2
WP_076617802.1\|2275725_2276610_-	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_076617806.1\|2276554_2277652_-	peptide chain release factor 1	W8EDB3	Pseudomonas_phage	3.1e-05	39.1
WP_076617810.1\|2277666_2278248_-	thymidine kinase	A0A249XZX5	Enterococcus_phage	3.5e-48	50.5
WP_076617813.1\|2278399_2279740_+	Mur ligase family protein	NA	NA	NA	NA
WP_076617816.1\|2279847_2280831_-	serine hydrolase	NA	NA	NA	NA
WP_076617820.1\|2281163_2283035_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	8.1e-62	32.8
WP_076617823.1\|2283034_2284756_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.2e-27	22.4
WP_076617826.1\|2284849_2285527_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_076617829.1\|2285527_2285737_+	hypothetical protein	NA	NA	NA	NA
WP_076617833.1\|2286452_2286638_+	hypothetical protein	A0A059T7Z0	Listeria_phage	4.3e-08	52.5
WP_076617836.1\|2287294_2288338_-	N-acetylmuramoyl-L-alanine amidase	A0A1G5SA77	Enterococcus_phage	6.2e-43	49.3
WP_076617839.1\|2288339_2288558_-	hypothetical protein	Q8W5Y9	Listeria_phage	1.8e-05	43.1
WP_076617843.1\|2288544_2288844_-	hypothetical protein	NA	NA	NA	NA
WP_076617848.1\|2288859_2289156_-	XkdX family protein	NA	NA	NA	NA
WP_076617851.1\|2289145_2290582_-	hypothetical protein	A0A1S5RCQ5	Lactobacillus_phage	4.4e-07	34.2
WP_076617855.1\|2290574_2290796_-	hypothetical protein	NA	NA	NA	NA
WP_076617858.1\|2290795_2290999_-	hypothetical protein	NA	NA	NA	NA
WP_076617863.1\|2290998_2294409_-	hypothetical protein	NA	NA	NA	NA
WP_076617866.1\|2294410_2295121_-	hypothetical protein	NA	NA	NA	NA
WP_076617869.1\|2295117_2298075_-	tape measure protein	A0A0P0IZN3	Lactobacillus_phage	4.2e-89	52.5
WP_076617873.1\|2298296_2298644_-	hypothetical protein	A0A290GJX3	Caldibacillus_phage	5.8e-22	45.6
WP_076617876.1\|2298699_2299299_-	hypothetical protein	E3W8G1	Leuconostoc_phage	1.3e-42	51.4
WP_076617880.1\|2299316_2299637_-	hypothetical protein	E4ZFM8	Streptococcus_phage	3.0e-17	47.9
WP_076617883.1\|2299633_2299996_-	HK97 gp10 family phage protein	A0A0U4II15	Exiguobacterium_phage	5.1e-29	56.3
WP_076617887.1\|2299982_2300291_-	hypothetical protein	NA	NA	NA	NA
WP_076617890.1\|2300277_2300580_-\|head,tail	phage gp6-like head-tail connector protein	A0A290FZN8	Caldibacillus_phage	1.6e-12	44.3
WP_076617894.1\|2300590_2301817_-\|capsid	phage major capsid protein	R9TQG7	Paenibacillus_phage	3.9e-97	47.5
WP_120270415.1\|2301806_2302637_-\|protease	Clp protease ClpP	Q9AZS8	Lactococcus_phage	3.9e-48	50.5
WP_076617902.1\|2302596_2303796_-\|portal	phage portal protein	A0A0P0IZM3	Lactobacillus_phage	7.7e-114	51.4
WP_076617906.1\|2303815_2305510_-\|terminase	terminase large subunit	A0A1B0Y6B8	Lactobacillus_phage	2.9e-236	68.4
WP_076617909.1\|2305502_2305871_-	hypothetical protein	A0A1B0YE76	Lactobacillus_phage	3.2e-23	50.8
WP_076617913.1\|2306069_2306408_-	HNH endonuclease	A0A1B0YEC6	Lactobacillus_phage	1.8e-28	61.7
WP_076617918.1\|2306484_2306790_+	hypothetical protein	NA	NA	NA	NA
WP_083685988.1\|2306958_2307327_-	hypothetical protein	NA	NA	NA	NA
WP_157886453.1\|2307364_2307526_-	hypothetical protein	NA	NA	NA	NA
WP_076617926.1\|2307562_2307796_-	hypothetical protein	NA	NA	NA	NA
WP_076617930.1\|2307807_2308098_-	hypothetical protein	NA	NA	NA	NA
WP_076614562.1\|2308111_2309239_-	DNA cytosine methyltransferase	A0A1I9KKE7	Lactobacillus_phage	1.1e-109	56.1
WP_076617934.1\|2309235_2309454_-	hypothetical protein	NA	NA	NA	NA
WP_076617938.1\|2309691_2310240_-	hypothetical protein	NA	NA	NA	NA
WP_076617943.1\|2310224_2310713_-	hypothetical protein	NA	NA	NA	NA
WP_076618950.1\|2310727_2311066_-	VRR-NUC domain-containing protein	A0A2P0ZLB6	Lactobacillus_phage	2.4e-36	65.7
WP_120270417.1\|2311338_2312589_-	helicase	A0A1B0Y896	Lactobacillus_phage	3.0e-129	54.1
WP_076617948.1\|2312566_2313388_-	bifunctional DNA primase/polymerase	A0A2P0ZLB0	Lactobacillus_phage	2.3e-69	50.4
WP_076617953.1\|2313399_2313909_-	hypothetical protein	A0A1B0Y6E2	Lactobacillus_phage	3.1e-32	44.8
WP_076617956.1\|2313908_2314616_-	AAA family ATPase	A0A2P0ZLB2	Lactobacillus_phage	4.4e-61	62.1
WP_076617960.1\|2314612_2315983_-	DEAD/DEAH box helicase	A0A0A1ENT0	Lactobacillus_phage	4.7e-160	60.7
WP_076617964.1\|2315983_2316463_-	siphovirus Gp157 family protein	A0A059T803	Listeria_phage	2.4e-26	44.0
WP_076617968.1\|2316446_2316626_-	hypothetical protein	NA	NA	NA	NA
WP_076617971.1\|2316881_2317091_-	hypothetical protein	NA	NA	NA	NA
WP_076617975.1\|2317151_2317436_+	hypothetical protein	NA	NA	NA	NA
WP_076617980.1\|2317519_2318302_-	phage antirepressor KilAC domain-containing protein	A0A1Q1PVU2	Staphylococcus_phage	2.6e-86	61.8
WP_076617984.1\|2318315_2318519_-	transcriptional regulator	NA	NA	NA	NA
WP_076617988.1\|2318778_2319105_+	helix-turn-helix transcriptional regulator	A0A1B0Y3N1	Lactobacillus_phage	2.8e-18	48.1
WP_076617991.1\|2319094_2319505_+	ImmA/IrrE family metallo-endopeptidase	D6PSS8	Lactobacillus_phage	2.5e-24	45.4
WP_076617995.1\|2319568_2320054_+	hypothetical protein	NA	NA	NA	NA
WP_076617999.1\|2320134_2320662_+	hypothetical protein	NA	NA	NA	NA
WP_076618003.1\|2320782_2321967_+\|integrase	site-specific integrase	A0A2P0ZL94	Lactobacillus_phage	1.0e-57	37.6
2322595:2322609	attR	NA	NA	NA	NA

DBSCAN-SWA_9

2335947 : 2343038

Lactobacillus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076618047.1\|2335947_2336274_-	heavy metal-binding domain-containing protein	M4STD1	Rhodobacter_phage	7.9e-05	33.7
WP_164510787.1\|2337040_2337181_+	hypothetical protein	O48431	Lactobacillus_phage	1.2e-07	67.4
WP_076618051.1\|2337605_2338328_+	SHOCT domain-containing protein	A0A141DZS3	Streptococcus_phage	6.4e-07	31.5
WP_076618054.1\|2338509_2339226_+	Ltp family lipoprotein	A0A173G9H4	Propionibacterium_phage	7.5e-08	71.1
WP_076618057.1\|2339291_2339480_-	CsbD family protein	NA	NA	NA	NA
WP_076618060.1\|2339513_2339759_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_076618065.1\|2339966_2340677_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_076618068.1\|2340759_2341929_-\|transposase	transposase	A0A0P0ICY9	Lactobacillus_phage	8.2e-145	68.3
WP_076618073.1\|2342102_2343038_-	NADP-dependent oxidoreductase	A0A0G2YAX3	Acanthamoeba_polyphaga_mimivirus	4.0e-09	28.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP019324

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP019324_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP019324_1

27820-27976

Orphan

Consensus_repeat	Method
AAACCCTTGCTGCGCGCAGAACTGTAAATTCTACAGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP019324_1

>merge|NZ_CP019324|1|27820-27976|CRISPRCasFinder
AAACCCTTGCTGCGCGCAGAACTGTAAATTCTACAGTTCAGCATGACACCGTTGAAACCCTTGCTGCGCGCAGAACTGTAAATTCTACAGTTCAGCATGACACCGTTGAAAAGGACGCTCAAACCCTTGCTGCGCGCAGAACTGTAAATTCTACAGT

>NZ_CP019324|1|1|27820-27976|CRISPRCasFinder
AAACCCTTGCTGCGCGCAGAACTGTAAATTCTACAGT	TCAGCATGACACCGTTGAAACCCTTGCTGCGCGCAGAACTGTAAATTCTACAGTTCAGCATGACACCGTTGAAAAGGACGCTC
AAACCCTTGCTGCGCGCAGAACTGTAAATTCTACAGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP019324.1\|WP_017866972.1\|26035_26821_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379293
NZ_CP019324.1\|WP_003649837.1\|25813_26029_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019324.1\|WP_076619063.1\|20706_22035_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340890
NZ_CP019324.1\|WP_076619047.1\|14873_15458_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|239737
NZ_CP019324.1\|WP_084988350.1\|14237_14765_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP019324.1\|WP_076619050.1\|24288_25527_-\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
NZ_CP019324.1\|WP_020090536.1\|17033_18239_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|369639
NZ_CP019324.1\|WP_068281289.1\|22693_24058_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|181958
NZ_CP019324.1\|WP_043023465.1\|15720_16746_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP019324.1\|WP_100215579.1\|19307_19781_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225511

Protein	Function_ID	Function_description	E-value
NZ_CP019324.1\|WP_017866972.1\|26035_26821_-\|AAA-family-ATPase	gnl\|CDD\|379293	pfam13614, AAA_31, AAA domain. This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.	2.22651e-36
NZ_CP019324.1\|WP_076619063.1\|20706_22035_+\|MFS-transporter	gnl\|CDD\|340890	cd17332, MFS_MelB_like, Salmonella enterica Na+/melibiose symporter MelB and similar transporters of the Major Facilitator Superfamily. This family is composed of Salmonella enterica Na+/melibiose symporter MelB, Major Facilitator Superfamily domain-containing proteins, MFSD2 and MFSD12, and other sugar transporters. MelB catalyzes the electrogenic symport of galactosides with Na+, Li+ or H+. The MFSD2 subfamily is composed of two vertebrate members, MFSD2A and MFSD2B. MFSD2A is more commonly called sodium-dependent lysophosphatidylcholine symporter 1 (NLS1). It is an LPC symporter that plays an essential role for blood-brain barrier formation and function. Inactivating mutations in MFSD2A cause a lethal microcephaly syndrome. MFSD2B is a potential risk or protect factor in the prognosis of lung adenocarcinoma. MelB-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.44815e-101
NZ_CP019324.1\|WP_076619047.1\|14873_15458_+\|recombinase-family-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	3.20275e-44
NZ_CP019324.1\|WP_076619050.1\|24288_25527_-\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.51647e-46
NZ_CP019324.1\|WP_020090536.1\|17033_18239_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|369639	pfam07992, Pyr_redox_2, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.	4.1919e-48
NZ_CP019324.1\|WP_068281289.1\|22693_24058_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|181958	PRK09564, PRK09564, coenzyme A disulfide reductase; Reviewed.	1.66032e-92
NZ_CP019324.1\|WP_043023465.1\|15720_16746_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	3.87757e-70
NZ_CP019324.1\|WP_100215579.1\|19307_19781_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.2719e-05

>NZ_CP019324.1|WP_017866972.1|26035_26821_-|AAA-family-ATPase
MNGKTLLNFNFKGGVGKTTLTVMETYLLGQEGKKVLLIDFDPQGNATEIMKETYKADLKPELSLYEGLLGGNLSKSIVSVTNQIDMIPTDWTLSLWIGAVEKVSRVKRNILLPQMLSKLKQNYDYIFIDVPPTINVFTNNAIMASDFISIVLQTQKQSYTSSLKTATHLGELREQYNGSFQLVGAILYLMKPRAKVDTEISAQAKDFFGEGVFSNSIRTQERVKTFANEGIRNKDHWDKRAIQMYQMVLNEQILRIQQLEE
>NZ_CP019324.1|WP_003649837.1|25813_26029_-|hypothetical-protein
MAEDFLNKVSKKASEQLKNLKSPYQFETERTKTVQLRMSTYKEVKRIAFENDEKIVDVLEKIIREGLAKRK
>NZ_CP019324.1|WP_076619050.1|24288_25527_-|ISL3-family-transposase
MSQLDNTLKLLGITDTNIQVFGTREEFNGRGSGRKKYLVIQAELTYTLRRCPSCGYNTLHPNGHKLTHVHISGPMDRPVILELNKQRWRCSNCHSTCTATTPVVSTNHAIGHGLATHVLKLASKSLPAKTIASLTGISTNSVQRILTANIHPHASRRLPINLCFDEFRSTHGSMSFICIDADTHKSVKVLSDRLNRTIKQFFLSQYSTAERAAVQRVIMDMNASYQAFVHELFPNAELIIDRFHIIQLMGRTMDTIRTQFLKQLDKHSREYKVLKSLWRLFHKATPDAQKSRYLFGLNEYSTEQNAIDIGTDTFPAFKTAYETYIDLHDALMGRHADELKNIITNYQPNGTPLDTAIHTLRKNLNGVINAAKSSYSNGPIEGINRKIKELKRACYGFSNQANMFTRVYQLIA
>NZ_CP019324.1|WP_068281289.1|22693_24058_+|FAD-dependent-oxidoreductase
MDKRKIVIVGASHGGHESAIELLDKYNDVDVTVYEAGDFISFMSCGMQLYLENKVTAEDDVRNFAPEDVEKKGGHVYANHEVTAIHPEHKTVTVKDLTNNSEEEVQYDKLILSSGVTPKFLPVPGNDLKNIYLMRGRDWASKLMSAVNNPAIKNVAIVGAGYIGTEASEVFAKAGKHVTLMDMIDRPLGTYLNPELLDVLEPTFKKNMDLKMGVKIEGFNGNEKVESVKTDQGDIPADLVVVSAGVTPNTDWIKGTVDLDQRGWIKTDPYLRTNVKDVYAIGDAILPLSIPAGKPMPIALATTARREAQYVVDHIFEDKPDRAFKGVIGASALSVFDYHFATAGLNKFSAAKNKLDYQTSFYEDHMRPAYVPEADNPKVYVSLTFNPYTHQILGGAVLSKYDITAQGNVLALAISHKMRLEDLAEQDFFFQPGFDRQWSLLNLAAQHALGMARF
>NZ_CP019324.1|WP_076619063.1|20706_22035_+|MFS-transporter
MKSTTKWVTRWPERISYGLSDAADNLVFQMMTTYLLFFYTDVYGLTPSAVAILFVVARVADVVESFVIGIMIDHTHSRFGKSRPFFLWYSLPYVIFAVLTFVTPNFSYNGKLIWAYVTYLGLGFLYTAVNLPITSILPTMSQNTRELTLLGVIRQFFGSSVQIVVAVFTLPLVAFFGHGNQQKGFLGTIIVFSLISFLLIINTFVHVRERFANPEIAHQPLTTVLKMLKHNQPWIVMSIVILMYWLVTAIKNQTTIYYFKYTVGNENLVPLANSFTLAALIGVLLIIRITEVRSKKQTMLRGILMALVGQAVIAIGVYTKILWFLFGGVLINSIGNGIIIGLVSIMIADTIRYGASMGIQAEGVLASTDDFGVNVGLGVGGLITAGLFHFSGYVANRTQNAATLTMIDLNYVWIPLVIYVGMYFVLRLYDEGRIERAIEARK
>NZ_CP019324.1|WP_100215579.1|19307_19781_-|helix-turn-helix-domain-containing-protein
MVKAQIINEHLSDGTSRAELARNHQLPKRQVNRWLQQYHLNGIETLKRYKTRRKFSAEFKWYVINYYQTHDESLAEVAGKYNVLACQISVWRKTLIRDGYSSLEPHPKGRSTKTKRSKKQIRQLEKQSEIERLRSEIAQKNQEFYDTKLENDILKNQ
>NZ_CP019324.1|WP_020090536.1|17033_18239_+|FAD-dependent-oxidoreductase
MSDLDQTNSYRYVIVGGGVVAGYAIKGIRQEDSEGEILIISQEADVPYERPALSKKLWLDDEFTEENIQIGAENYPNVTFKFKTTVTAINRQDKVITLADSEQIKYEQLLLATGGEPRQIQGPSDPHVLVFRQWSDYRKLRKFSGPNKRVVIIGGGYVGTELASSLTQNETEVTMIFPEKALGEGKFPESIRTEYEATFKRNGVTLMSGQFVQSYQRQGDHLALLTKDGTVIAADTIIVGLGVTPRISLAEDSCLDLADGGVKVNEYLNTSDPAIWSAGDIASYPDHILGRQRIEHVDHARLSGELVGRNMAGAHMSYQHTPYFYSMIFDISWQAIGNIDPKLQLIFDRRTHGSLVYFIDTDKLVGVLVWNVKVNLDDVRALLANAPATDDLVGSIREKKA
>NZ_CP019324.1|WP_043023465.1|15720_16746_+|IS30-family-transposase
MTRIKNIISNQYHQLNLAERGRIEALRGLDWSIRRIAKALHRNPSTISRELRRGTTTQINANTRIFEQSYLAETGEAVYRKHRLNSCYRGLFDHCQTFCNALVTALKARPRMHSVDTFVHQFKTNYPGVVCPSTPTVYRYIDDQRLTIRNSDLPAKLRRRVKRPGTKHHRINKKNLGHSIEERPTVVQARQELGHWEGDLVKGKRVESEPALMTLTERVSRLEIIVKLPNYHADTCLKALQNTLYDYGTEYFKTITFDNGAEFSSLSQVAGTDIYFAHPYSPWERGTNENTNGLLREFFPKGRSLVLASLIDIQLAQDTLNNRLRRSLNYRCPADLMPELA
>NZ_CP019324.1|WP_076619047.1|14873_15458_+|recombinase-family-protein
MAKIGYARVSSKEQHLDRQLAALKGVDKLFTDKLSGANTNRPELQKMLAYIREGDIVLVTELDRLGRNNHDLTKIMNSIQNKGATLDVLNLPSMTGIADPNLRQLMTNLIIELYKYQAESERKRIIERQQQGIALAKQQGKYHGRKPQYTQDDPRLQHAFKLYQTGMSDVDVARNTGIKRTTFIRYRKKFNIQR
>NZ_CP019324.1|WP_084988350.1|14237_14765_+|hypothetical-protein
MVTDKKFYLYRKLLPYIIRVKLRLCKDSNSKTTHTTRSWTYRLFLLFIDKIKSKNYKKQYEDKDLYPYLQMVNIQNGDEIAATGFIPIKSHEMRTIVIPKGRFLDAVKNRLTSNYKALKRFVNKKPVYIYFIYQTMSGTVKEFVVETDYQDSLGKDLDMEYLTKILAVQDKYKTK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP019324_1	1.1\|27857\|83\|NZ_CP019324\|CRISPRCasFinder	27857-27939	83	NZ_CP014927	Lactobacillus paracollinoides strain TMW 1.1995 plasmid pL11995-3, complete sequence	35518-35600	23	0.723
NZ_CP019324_1	1.1\|27857\|83\|NZ_CP019324\|CRISPRCasFinder	27857-27939	83	NZ_CP014928	Lactobacillus paracollinoides strain TMW 1.1995 plasmid pL11995-4, complete sequence	27242-27324	23	0.723
NZ_CP019324_1	1.1\|27857\|83\|NZ_CP019324\|CRISPRCasFinder	27857-27939	83	NZ_CP014932	Lactobacillus paracollinoides strain TMW 1.1995 plasmid pL11995-8, complete sequence	38859-38941	23	0.723
NZ_CP019324_1	1.1\|27857\|83\|NZ_CP019324\|CRISPRCasFinder	27857-27939	83	NZ_CP014918	Lactobacillus paracollinoides strain TMW 1.1994 plasmid pL11994-3, complete sequence	5543-5625	23	0.723
NZ_CP019324_1	1.1\|27857\|83\|NZ_CP019324\|CRISPRCasFinder	27857-27939	83	NC_022114	Lactobacillus paracasei subsp. paracasei 8700:2 plasmid 1, complete sequence	579-661	23	0.723
NZ_CP019324_1	1.1\|27857\|83\|NZ_CP019324\|CRISPRCasFinder	27857-27939	83	NZ_CP019324	Lactobacillus allii strain WiKim39 plasmid pWIKIM01, complete sequence	27857-27939	23	0.723
NZ_CP019324_1	1.1\|27857\|83\|NZ_CP019324\|CRISPRCasFinder	27857-27939	83	NZ_CP031201	Lactobacillus brevis strain UCCLBBS449 plasmid pUCCLBBS449_C, complete sequence	6996-7078	24	0.711

1. spacer 1.1|27857|83|NZ_CP019324|CRISPRCasFinder matches to NZ_CP014927 (Lactobacillus paracollinoides strain TMW 1.1995 plasmid pL11995-3, complete sequence) position: , mismatch: 23, identity: 0.723

tcagcatgacaccgttgaaacccttgctgcgcgcagaactgtaaattctacagttcagca	CRISPR spacer
tcagcatgacaccgttgaaacccttgctgcgcgcagaactgtaaattctacagttcagca	Protospacer
************************************************************

2. spacer 1.1|27857|83|NZ_CP019324|CRISPRCasFinder matches to NZ_CP014928 (Lactobacillus paracollinoides strain TMW 1.1995 plasmid pL11995-4, complete sequence) position: , mismatch: 23, identity: 0.723

tcagcatgacaccgttgaaacccttgctgcgcgcagaactgtaaattctacagttcagca	CRISPR spacer
tcagcatgacaccgttgaaacccttgctgcgcgcagaactgtaaattctacagttcagca	Protospacer
************************************************************

3. spacer 1.1|27857|83|NZ_CP019324|CRISPRCasFinder matches to NZ_CP014932 (Lactobacillus paracollinoides strain TMW 1.1995 plasmid pL11995-8, complete sequence) position: , mismatch: 23, identity: 0.723

tcagcatgacaccgttgaaacccttgctgcgcgcagaactgtaaattctacagttcagca	CRISPR spacer
tcagcatgacaccgttgaaacccttgctgcgcgcagaactgtaaattctacagttcagca	Protospacer
************************************************************

4. spacer 1.1|27857|83|NZ_CP019324|CRISPRCasFinder matches to NZ_CP014918 (Lactobacillus paracollinoides strain TMW 1.1994 plasmid pL11994-3, complete sequence) position: , mismatch: 23, identity: 0.723

tcagcatgacaccgttgaaacccttgctgcgcgcagaactgtaaattctacagttcagca	CRISPR spacer
tcagcatgacaccgttgaaacccttgctgcgcgcagaactgtaaattctacagttcagca	Protospacer
************************************************************

5. spacer 1.1|27857|83|NZ_CP019324|CRISPRCasFinder matches to NC_022114 (Lactobacillus paracasei subsp. paracasei 8700:2 plasmid 1, complete sequence) position: , mismatch: 23, identity: 0.723

tcagcatgacaccgttgaaacccttgctgcgcgcagaactgtaaattctacagttcagca	CRISPR spacer
tcagcatgacaccgttgaaacccttgctgcgcgcagaactgtaaattctacagttcagca	Protospacer
************************************************************

6. spacer 1.1|27857|83|NZ_CP019324|CRISPRCasFinder matches to NZ_CP019324 (Lactobacillus allii strain WiKim39 plasmid pWIKIM01, complete sequence) position: , mismatch: 23, identity: 0.723

tcagcatgacaccgttgaaacccttgctgcgcgcagaactgtaaattctacagttcagca	CRISPR spacer
tcagcatgacaccgttgaaacccttgctgcgcgcagaactgtaaattctacagttcagca	Protospacer
************************************************************

7. spacer 1.1|27857|83|NZ_CP019324|CRISPRCasFinder matches to NZ_CP031201 (Lactobacillus brevis strain UCCLBBS449 plasmid pUCCLBBS449_C, complete sequence) position: , mismatch: 24, identity: 0.711

tcagcatgacaccgttgaaacccttgctgcgcgcagaactgtaaattctacagttcagca	CRISPR spacer
tcagcatgacaccgttgaatcccttgctgcgcgcagaactgtaaattctacagttcagca	Protospacer
******************* ****************************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 16746

Streptococcus_phage(33.33%)

transposase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010014831.1\|898_1180_+	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_010620892.1\|1226_1412_+	hypothetical protein	NA	NA	NA	NA
WP_076619036.1\|1408_2089_+	zeta toxin family protein	NA	NA	NA	NA
WP_068479060.1\|2078_2357_-	hypothetical protein	NA	NA	NA	NA
WP_003555660.1\|2379_2607_-	hypothetical protein	NA	NA	NA	NA
WP_076619041.1\|2860_4924_+	MobA/MobL family protein	NA	NA	NA	NA
WP_083686034.1\|4952_6557_+	type IA DNA topoisomerase	A0A1X9I6W8	Streptococcus_phage	4.5e-109	46.6
WP_027823051.1\|6679_6895_+	hypothetical protein	NA	NA	NA	NA
WP_003577000.1\|8874_10722_-	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	4.4e-60	29.1
WP_045353638.1\|11039_11300_+\|transposase	transposase	A0A1P8CWP5	Bacillus_phage	4.2e-09	39.3
WP_157886458.1\|11356_12115_+\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	3.6e-32	35.5
WP_076619057.1\|12360_12522_+	LtrC-like protein	NA	NA	NA	NA
WP_016378676.1\|12660_12765_-\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_120270481.1\|13304_14103_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_084988350.1\|14237_14765_+	hypothetical protein	NA	NA	NA	NA
WP_076619047.1\|14873_15458_+	recombinase family protein	M4QQC6	Vibrio_phage	4.5e-19	42.8
WP_043023465.1\|15720_16746_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	5.7e-41	35.5

DBSCAN-SWA_2

22693 : 26821

Erysipelothrix_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_068281289.1\|22693_24058_+	FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	1.2e-09	22.6
WP_076619050.1\|24288_25527_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	2.0e-40	29.9
WP_003649837.1\|25813_26029_-	hypothetical protein	NA	NA	NA	NA
WP_017866972.1\|26035_26821_-	AAA family ATPase	F0PIG8	Enterococcus_phage	2.0e-30	35.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP019323

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP019324

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection