CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP018199	Staphylococcus succinus strain 14BME20 chromosome, complete genome	1 crisprs	csa3,DEDDh,cas3,DinG,WYL	1	0	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP018199_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018199_1

123867-123992

Orphan

Consensus_repeat	Method
CCGAGCGATGATGGAACAGGAGACACTTCACAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018199_1

>merge|NZ_CP018199|1|123867-123992|CRISPRCasFinder
CCGAGCGATGATGGAACAGGAGACACTTCGCAGCCCGATGATACGGATCAAGACAACAGTGATGGAACCGAGGAACCAACGGAGCCCGATAAACCAAGTGATGGGGGAACAGGAGAGCCAACGCAA

>NZ_CP018199|1|1|123867-123992|CRISPRCasFinder
CCGAGCGATGATGGAACAGGAGACACTTCGCAG	CCCGATGATACGGATCAAGACAACAGTGATGGAACCGAGGAACCAACGGAGCCCGATAAA
CCAAGTGATGGGGGAACAGGAGAGCCAACGCAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018199.1\|WP_073504071.1\|119428_119566_-\|cyclic-lactone-autoinducer-peptide	unknown	unknown	gnl\|CDD\|129030
NZ_CP018199.1\|WP_073504066.1\|113813_114776_+\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380484
NZ_CP018199.1\|WP_073504074.1\|122089_122719_-\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|226090
NZ_CP018199.1\|WP_073504068.1\|116355_117321_+\|carbohydrate-kinase	unknown	unknown	gnl\|CDD\|238572
NZ_CP018199.1\|WP_046837554.1\|126085_126373_+\|co-chaperone-GroES	unknown	unknown	gnl\|CDD\|178988
NZ_CP018199.1\|WP_073504073.1\|121116_121902_-\|carbon-nitrogen-family-hydrolase	unknown	unknown	gnl\|CDD\|143607
NZ_CP018199.1\|WP_073504070.1\|118108_119404_-\|GHKL-domain-containing-protein	unknown	unknown	gnl\|CDD\|225519
NZ_CP018199.1\|WP_046838128.1\|113439_113667_+\|sulfurtransferase-TusA-family-protein	unknown	unknown	gnl\|CDD\|223502
NZ_CP018199.1\|WP_046837558.1\|130660_130849_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018199.1\|WP_073504078.1\|128862_130152_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|181512
NZ_CP018199.1\|WP_073504082.1\|133011_133884_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP018199.1\|WP_073504077.1\|126426_128052_+\|chaperonin-GroEL	unknown	unknown	gnl\|CDD\|234573
NZ_CP018199.1\|WP_073504072.1\|119562_120138_-\|accessory-gene-regulator-AgrB	unknown	unknown	gnl\|CDD\|214819
NZ_CP018199.1\|WP_046837556.1\|128318_128786_+\|bacillithiol-transferase-BstA	unknown	unknown	unknown
NZ_CP018199.1\|WP_073504069.1\|117379_118096_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225818
NZ_CP018199.1\|WP_073504067.1\|114874_116359_+\|sucrose-6-phosphate-hydrolase	unknown	unknown	gnl\|CDD\|273554
NZ_CP018199.1\|WP_073504081.1\|132328_132997_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379133
NZ_CP018199.1\|WP_073504076.1\|125164_125908_-\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP018199.1\|WP_073504080.1\|131425_132310_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_CP018199.1\|WP_073504079.1\|131048_131429_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224639

Protein	Function_ID	Function_description	E-value
NZ_CP018199.1\|WP_073504071.1\|119428_119566_-\|cyclic-lactone-autoinducer-peptide	gnl\|CDD\|129030	smart00794, AgrD, Staphylococcal AgrD protein. This family consists of several AgrD proteins from many Staphylococcus species. The agr locus was initially described in Staphylococcus aureus as an element controlling the production of exoproteins implicated in virulence. Its pattern of action has been shown to be complex, upregulating certain extracellular toxins and enzymes expressed post-exponentially and repressing some exponential-phase surface components. AgrD encodes the precursor of the autoinducing peptide (AIP).The AIP derived from AgrD by the action of AgrB interacts with AgrC in the membrane to activate AgrA, which upregulates transcription both from promoter P2, amplifying the response, and from P3, initiating the production of a novel effector: RNAIII. In S. aureus, delta-hemolysin is the only translation product of RNA III and is not involved in the regulatory functions of the transcript, which is therefore the primary agent for modulating the expression of other operons controlled by agr.	9.3994e-18
NZ_CP018199.1\|WP_073504066.1\|113813_114776_+\|LacI-family-transcriptional-regulator	gnl\|CDD\|380484	cd01542, PBP1_TreR-like, ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators. Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators. The ligand-binding domain of TreR is structurally homologous to the periplasmic sugar-binding domain of ABC-type transporters and both domains contain the type 1 periplasmic binding protein-like fold. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the type 1 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	1.90188e-96
NZ_CP018199.1\|WP_073504074.1\|122089_122719_-\|nitroreductase-family-protein	gnl\|CDD\|226090	COG3560, FMR2, Predicted oxidoreductase related to nitroreductase [General function prediction only].	8.50189e-103
NZ_CP018199.1\|WP_073504068.1\|116355_117321_+\|carbohydrate-kinase	gnl\|CDD\|238572	cd01167, bac_FRK, Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into glucose-6-phosphate. This is in contrast to FRKs [or ketohexokinases (KHKs)] from mammalia and halophilic archaebacteria, which phosphorylate fructose to fructose-1-phosphate.	7.25255e-102
NZ_CP018199.1\|WP_046837554.1\|126085_126373_+\|co-chaperone-GroES	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	1.12038e-43
NZ_CP018199.1\|WP_073504073.1\|121116_121902_-\|carbon-nitrogen-family-hydrolase	gnl\|CDD\|143607	cd07583, nitrilase_5, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	1.1524e-122
NZ_CP018199.1\|WP_073504070.1\|118108_119404_-\|GHKL-domain-containing-protein	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	4.93737e-23
NZ_CP018199.1\|WP_046838128.1\|113439_113667_+\|sulfurtransferase-TusA-family-protein	gnl\|CDD\|223502	COG0425, SirA, Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones].	7.90959e-18
NZ_CP018199.1\|WP_073504078.1\|128862_130152_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|181512	PRK08637, PRK08637, hypothetical protein; Provisional.	0
NZ_CP018199.1\|WP_073504077.1\|126426_128052_+\|chaperonin-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NZ_CP018199.1\|WP_073504072.1\|119562_120138_-\|accessory-gene-regulator-AgrB	gnl\|CDD\|214819	smart00793, AgrB, Accessory gene regulator B. The accessory gene regulator (agr) of Staphylococcus aureus is the central regulatory system that controls the gene expression for a large set of virulence factors. The arg locus consists of two transcripts: RNAII and RNAIII. RNAII encodes four genes (agrA, B, C, and D) whose gene products assemble a quorum sensing system. At low cell density, the agr genes are continuously expressed at basal levels. A signal molecule, autoinducing peptide (AIP), produced and secreted by the bacteria, accumulates outside of the cells. When the cell density increases and the AIP concentration reaches a threshold, it activates the agr response, i.e. activation of secreted protein gene expression and subsequent repression of cell wall-associated protein genes. AgrB and AgrD are essential for the production of the autoinducing peptide which functions as a signal for quorum sensing. AgrB is a transmembrane protein. AgrB is involved in the proteolytic processing of AgrD and may have both proteolytic enzyme activity and a transporter facilitating the export of the processed AgrD peptide.	3.23736e-55
NZ_CP018199.1\|WP_073504082.1\|133011_133884_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	5.45046e-68
NZ_CP018199.1\|WP_073504069.1\|117379_118096_-\|response-regulator-transcription-factor	gnl\|CDD\|225818	COG3279, LytT, Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms].	4.71484e-52
NZ_CP018199.1\|WP_073504067.1\|114874_116359_+\|sucrose-6-phosphate-hydrolase	gnl\|CDD\|273554	TIGR01322, Sucrose-6-phosphate_hydrolase, sucrose-6-phosphate hydrolase. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	0
NZ_CP018199.1\|WP_073504081.1\|132328_132997_+\|hypothetical-protein	gnl\|CDD\|379133	pfam13346, ABC2_membrane_5, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	0.00571165
NZ_CP018199.1\|WP_073504076.1\|125164_125908_-\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	9.86286e-13
NZ_CP018199.1\|WP_073504080.1\|131425_132310_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	5.13994e-65
NZ_CP018199.1\|WP_073504079.1\|131048_131429_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|224639	COG1725, COG1725, Predicted transcriptional regulators [Transcription].	1.05373e-37

>NZ_CP018199.1|WP_073504074.1|122089_122719_-|nitroreductase-family-protein
MGLFSKNTSSLTTFQNAIESRRTIYSLDQDISISDNEVESIIEHAIKHVPSSFNSQSTRIVLLLNDNHNKFWDIAKDELKKVMGDDRDFQPTSDKIDNFKHSHGTILYFEDQEVIEGLQNQMPNYAENFAIWSSQTNAMHQFAIWTALSTEGVGASLQHYNPLVDAAVTEAFEIPNTWKLVAQMPFGNIREEAGDKEFHDVSKRFLVRK
>NZ_CP018199.1|WP_073504073.1|121116_121902_-|carbon-nitrogen-family-hydrolase
MNIEIFQFKVEPANVSLNEETITNWFAEYVTSETDIVVLPEMWNNGYALPQLKELSDNQLSRSFEFISKLAIQYKVDVIAGSVSNNLKGDIYNTAFAVSRNGYLINSYNKVHLVPMLNEPSYLSAGNAVPEAFTLSNGAKVTQIICYDLRFPELLRYPARKEAQIVFYVAQWPEVRVDHWTALLKARAIENDIYVVACNGCGDDGKTQYAGHSLVINPNGEIIAQLKDKPDHLSCTLDLDEVTAQREAIPVFKNLRPHLYK
>NZ_CP018199.1|WP_073504072.1|119562_120138_-|accessory-gene-regulator-AgrB
MSKLIDNKIDKFSKYLQQRNNLEHIEYLKMRLGMQVVVSNFFKALVTYGVSILCHLFLYTLTVHLSYFFIRLYAHGAHAKSSLLCHMQNLLFFVLLPWLLGYMNVSSLFMYSLAIIGFVVLVIYAPAETKKQPIPIRLKKRKKEKTIVVTLLLLIISVFFKDSYQQLILLGIVLIAGTQLPIFFPKEDVKS
>NZ_CP018199.1|WP_073504071.1|119428_119566_-|cyclic-lactone-autoinducer-peptide
MNILESLLTLITKFFSVLGATAGALPCGGFFDEPEVPSEITKLHE
>NZ_CP018199.1|WP_073504070.1|118108_119404_-|GHKL-domain-containing-protein
MTILSSISLSVFQAVILFIVIKIINKIKYTFWDYISIIGIIIPSTIGFYFFHEKAMIFLLTCSAVYIYFKNRIIGVVSILISFFILYIANFITTWLATLTYDLIKLNFVFNSLYLLVFAAITLAFSFITRYFIRKLLSSDLSFNKIYLTIVAIFLLTGLIILNVYLPNRIMSFADIKFLAVMYAVFIITIAILIITISFSIIRQIQYKRNMQEIENYYKYTLQIENINNEMRKFRHDYVNILSTMSEFIRESDMDGLKKYFNEEILPMQDSMQMNTIKINGIENLKVREIKGLLTTKILQAQEKNIRISIEVPEPIERIDMPIINLSRVIGIVLDNAIEASEKIEDDPLIRIAFIKNNDDSVMFIVMNKCEPNMPRIHTLFQENFSTKGKNRGLGLSTLKELTDATSNVLLDTTIDNDYFIQKVEILNSDS
>NZ_CP018199.1|WP_073504069.1|117379_118096_-|response-regulator-transcription-factor
MKIFICEDDTRQRENMISIINNYIMIEEKPMQIEVATDDPYEILERSKNTSDIGCYFLDIQLNSDINGIKLASEIRKYDPVGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPDELKSRIIDCLNTSESRLKLLSKESNVETIELKRGSNSVYVQYDDVMFFESSTKSHRLIAHLDNRQIEFYGNLKELDQLDDRFFRCHNSFVINRHNIESIDSKSRIVYFKNNEHCYASVRNVKKI
>NZ_CP018199.1|WP_073504068.1|116355_117321_+|carbohydrate-kinase
MKRLLAIGEALIDFIPNTTDSKLKDVEGFSRQVGGAPCNVASATTKLGGNAEMITQLGNDAFGDLIVETIEDIGVNTNYIKRTNDANTALAFVSLTKEGERDFSFYRKPSADMLYQPEYIQDIDVTQDDVLHFCSVDLVESPMKQAHKALIEKVSIAGGTIVFDPNVRLPLWENEADCKHAIQEFIPLANIVKISDEELTFVTGQNEELQAIQWLFQGEVEAVVYTKGPDGAVIYLKDGTVIEQPGFKVTAVDTTGAGDAFIGALISKLLTSERNEPIQLLKNNGHAILEFSNYVAAMVTTQYGAIGSIPTIDEVNKALIK
>NZ_CP018199.1|WP_073504067.1|114874_116359_+|sucrose-6-phosphate-hydrolase
MTEWTREKRYQRYEEVDQQTIDILTDQVEQSKYRQTFHIQPKTGLLNDPNGLIYFNGVYYVSHQWFPLGPVHGLKYWYTYTSKDLIHFNAEGPSLKPDTRDDSHGVYSGSAFEYNENLYYMYTANHRDNDWNRISTQHIAKVNHDGSVEKFPKAVISAPPEGYTQHFRDPKVFTKDGVFYAIIAAQNDLEQGRILQYYSTDIVNWELQGEIQTNLEAFGYMWECPDYFDLDGHDLMLFCPQGIEPSGEQFRNIYQSGYIMGQYDLNQLKMNHADFHELDYGFDFYAPQTFLDENGQRILIGWMGLPEINYPSDKDGWAHCLTIPRVLSVEEGNLKQRPIKALEQLRTNKETALGYANKFTRQLHPYDGKQYELIIDILENEATEIYFEVRTSKSQTTLITYNTRAKKVTLDRSESGKLPEHVDGATRSTYLDTSLSNLQIFIDTSSIEIFCNNGERVMTSRIFTDDDATGIKASTESGQVYLRFTKYDLKDDEG
>NZ_CP018199.1|WP_073504066.1|113813_114776_+|LacI-family-transcriptional-regulator
MKNIADIAKIAGVSKSTVSRYLNNGSVSVKTKQKLDKIIQENDYQPNQFAQSLRAHRTNMIGAIIPRMNSYAVDETIKGVKSVCNDLNYRLLLNYTNLDVELEIDALETFYRSKVDGIILMATEITQRHLEVINKINVPVIIVGQEHKDLHCIIHDDFHAGYLVGDIIGTKGYKDIQFFGVTESDIAVGIHRKEGLIAGLRTHGITPHISHTSFNYKEAMIDVASELETHTHYDAVVGATDSIALAVHKFTSEHKNQLKNQLIVGFGGDPVTEIVSPSISTVIYHFEQAGEVSMNKLNQMIQQQHIETRITIDVTLSFKR
>NZ_CP018199.1|WP_046838128.1|113439_113667_+|sulfurtransferase-TusA-family-protein
MVYELGTVGMVCPFPLIEAQKKMNTLDNGDELKIDFDCTQATEALPNWAAEQGYPITNYEQLDDASWTITIQKSE
>NZ_CP018199.1|WP_073504076.1|125164_125908_-|CPBP-family-intramembrane-metalloprotease
MSRIWVSILTLIIYGLAQFGVAFIQMAGLFNNFTGKELLFANIYAQVALFIIAAVIIIIINNFIANPTRLEQQPKEKKRYVILWAIIGYVIVMIYQVVAGVINMYVFGAPNKSPNTERLMKVANEIPIFIILISIVGPILEEFVFRKVIFGELYNIMKGNKTLRFLVAAIVSSIIFSAAHGDPSFFMIYFGMGFIFAALYAYTKRIWVPILVHIMQNGFVVIIQVFLGPEKIKELQESASFILHFLY
>NZ_CP018199.1|WP_046837554.1|126085_126373_+|co-chaperone-GroES
MLKPLGSRVVIQKTEQEQTTKSGIVLTDSAKEKSNEGTIIAVGAGRTLEDGSRIAPEVKEGDKVVFQQFAGTEVKRGDETYLIVNDDDILAVIEA
>NZ_CP018199.1|WP_073504077.1|126426_128052_+|chaperonin-GroEL
MAKDLKFSEDARQSMLRGVDKLANAVKVTIGPKGRNVVLDKEYTSPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGLRQGIDKAVDVAINALHEISQKVDNKNEIAQVGAISAADEEIGKYISEAMEKVGNDGVITIEESSGFNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYILITDKKISSFQDILPLLEQVVQASRPILIVADDVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGAQVITDDLGLELKDATIDMLGTSNKAEITKDNTTIVDGNGDQNSIDARVSQIKSQIEETDSEFDKEKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALNSTRAAVEEGIVAGGGTALMNIYDKVAQIDAEGDVATGINIVLKALEAPVRQIAENAGLEGSIIVERLKNAEVNVGFNAATNEWGNMLEAGIVDPTKVTRSSLQHAASVAAMFLTTEAVVARIPEETNNDAQAGGMGGMPGMM
>NZ_CP018199.1|WP_046837556.1|128318_128786_+|bacillithiol-transferase-BstA
MTNKSVYEVIDSGINYIITGYDNWNNEQVLDDKIDAFPNTIHWQYGHVLTIFETVLSLCEQNEVDVAKYTKLFGYGSSPDKWGDADIPSVDEIFTHLKTLGERARKLTDQQLEAELTETIAGCSTLDELLVLNAIHIPIHAGKIEEMSRLLRQQQ
>NZ_CP018199.1|WP_073504078.1|128862_130152_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MNPLALDLNEQLSKSNPEVADMLSDLGKLMYYPKGILSQSAEAKSTQYNATIGMATYSDSKMYANTLNDMFNHLEPDDIFPYAPPQGIEPLRDLWQQKMLKENPDLDKKDMTRPILTNALTHGLSLVGDMFVDSGDTLLLPTHNWGNYKLVYSTRHNAEIETYDIFDEEGHFTTEALVNTLENYKKDKVILILNYPNNPTGYTPTQGEVTTIVNAIKSLAERGTNVIALVDDAYYGLFYEDVYTQSLFTALTNLHLDNILPIRLDGATKEFFAWGLRVGFITFGINNEITKQVLEAKVKGMIRSNISSGPMPSQSAVKYVLEHSETFNKEIQQNIDTLQARYEVTKAVVYDDKYAQFWQPYDFNSGYFMALQVKDVDPEQLRKHLIDQYSIGIIALNATDIRIAFSCVEKDDIPHVFDTIAKAIADLQN
>NZ_CP018199.1|WP_046837558.1|130660_130849_+|hypothetical-protein
MKHLTKIFVIIALISFVVGYYLQATGHESSGIKLLIAAIMFMICAFINRNNNRRQRNNQQKK
>NZ_CP018199.1|WP_073504079.1|131048_131429_+|GntR-family-transcriptional-regulator
MKILLKNSSESPIYEQIKQQIKENILKGYVAPGEDLPSMRELAQDLSVSVITTKRAYEDLEKDGFVYTIRGKGTYVKEQDSAILKEKQFIVIESLAKSMTNEAKSIDMPLCELQEILAMIYEEDTE
>NZ_CP018199.1|WP_073504080.1|131425_132310_+|ABC-transporter-ATP-binding-protein
MNAIELNAITYRRKAFELNDISFRVPQGFVTGFIGSNGVGKTTIIRMIMDLIEPENGEILIFNETMKDNAVGIKNKIGFIYSDLYLNDKWTIKKAESYIAPFYSHWNHTLFLDYLEKFNLPYKRKIKTFSTGMKMKLSIAIAFSHNAKLFILDEPTSGLDPIVRNEVLDIIQKELIDENKSVFISTHIISDLEKIADYLVYIKNGEIVLNEFLDDILNKFKVVKGDPQHLDDELKQLTYYLEEHKTGYIALTEHANVFSEIFGGSVTITKPTIEDLMVYLEKGTHKYNHPIDES
>NZ_CP018199.1|WP_073504081.1|132328_132997_+|hypothetical-protein
MKNLLIRNFKLRKWTIILYAILLIISPLQLVIDNNNTFTQTLYASVAMILLFVSLLDSGHVFRFYSKLGHKHTYDFFGSLPVSKKALLNANYLTILIFTIVGASILSLYNMPNSDIAKNTINISFTLPFSYITLNFLAVPIAFKRYTEQKSEYISFLTYLLVMLILIPFAIVLILISMSELYDYHFVNSNYFENSLNYGFLAVSIIFFVANYFIQYNKLNKY
>NZ_CP018199.1|WP_073504082.1|133011_133884_+|ABC-transporter-ATP-binding-protein
MQLQDITKTFGNNNVLNHIDFDFGKSRIVGLIGKNGVGKTTLMKVMNGNIVNYKGEVKLGNKENVGYLIEHPKLYDNKSGLYNLKLFSHVLGKGFDKKYTDYIIDAFGMRPYIKKKVKKYSMGMKQKLAIAISLMNKPKYLILDEPTNGMDPDGSIDVLKTIETLVQDLDMKILISSHKLEDIELICDRAVFLSDGNFVQDVDMREGTPTDSTILIVAKKDFEKSLEYLNQAFEVIQSEQASGEIILTAQKNYQKILKGLANIEVFPEFIETRKSSLRDTYFNINKKGGQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP018199_1	1.1\|123900\|60\|NZ_CP018199\|CRISPRCasFinder	123900-123959	60	NZ_CP018199.1	123360-123419	1	0.983
NZ_CP018199_1	1.1\|123900\|60\|NZ_CP018199\|CRISPRCasFinder	123900-123959	60	NZ_CP018199.1	123495-123554	1	0.983
NZ_CP018199_1	1.1\|123900\|60\|NZ_CP018199\|CRISPRCasFinder	123900-123959	60	NZ_CP018199.1	123765-123824	1	0.983
NZ_CP018199_1	1.1\|123900\|60\|NZ_CP018199\|CRISPRCasFinder	123900-123959	60	NZ_CP018199.1	123630-123689	2	0.967

1. spacer 1.1|123900|60|NZ_CP018199|CRISPRCasFinder matches to position: 123360-123419, mismatch: 1, identity: 0.983

cccgatgatacggatcaagacaacagtgatggaaccgaggaaccaacggagcccgataaa	CRISPR spacer
cccgatgatacggatcaagacaacagtgatggaaccgaggaaccaacggagccagataaa	Protospacer
***************************************************** ******

2. spacer 1.1|123900|60|NZ_CP018199|CRISPRCasFinder matches to position: 123495-123554, mismatch: 1, identity: 0.983

cccgatgatacggatcaagacaacagtgatggaaccgaggaaccaacggagcccgataaa	CRISPR spacer
cccgatgatacggatcaagacaacagtgatggaaccgaggaaccaacggagccagataaa	Protospacer
***************************************************** ******

3. spacer 1.1|123900|60|NZ_CP018199|CRISPRCasFinder matches to position: 123765-123824, mismatch: 1, identity: 0.983

cccgatgatacggatcaagacaacagtgatggaaccgaggaaccaacggagcccgataaa	CRISPR spacer
cccgatgatacggatcaagacaacagtgatggaaccgaggaaccaacggagccagataaa	Protospacer
***************************************************** ******

4. spacer 1.1|123900|60|NZ_CP018199|CRISPRCasFinder matches to position: 123630-123689, mismatch: 2, identity: 0.967

cccgatgatacggatcaagacaacagtgatggaaccgaggaaccaacggagcccgataaa	CRISPR spacer
cctgatgatacggatcaagacaacagtgatggaactgaggaaccaacggagcccgataaa	Protospacer
**.********************************.************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

262170 : 276008

Staphylococcus_phage(92.31%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_073504163.1\|262170_263556_+	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.0e-165	59.5
WP_073504164.1\|263572_264577_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	1.3e-95	50.8
WP_046836774.1\|264573_264810_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	1.1e-29	74.7
WP_073504165.1\|264870_265347_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	5.5e-47	55.7
WP_073505777.1\|265354_266134_+	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	2.7e-99	69.8
WP_073504166.1\|266184_267774_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	5.0e-262	83.1
WP_046836771.1\|268151_269348_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	2.8e-193	86.6
WP_073504167.1\|269435_270344_+	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	2.4e-96	81.0
WP_073504168.1\|270548_271385_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	2.1e-110	68.2
WP_073504169.1\|271514_271871_-	CrcB family protein	NA	NA	NA	NA
WP_073504170.1\|271867_272233_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.3e-36	63.6
WP_073504171.1\|272300_272606_-	hypothetical protein	NA	NA	NA	NA
WP_046836765.1\|272895_273609_+	transaldolase	R9TM64	Synechococcus_phage	6.5e-20	37.0
WP_073504172.1\|273926_274562_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_073504173.1\|274643_275093_+	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	1.4e-20	44.7
WP_073504174.1\|275101_275524_-	hypothetical protein	NA	NA	NA	NA
WP_073504175.1\|275537_276008_-	sigma-70 family RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	1.8e-26	47.4

DBSCAN-SWA_2

280800 : 295490

Staphylococcus_phage(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_073504178.1\|280800_281844_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	4.6e-131	64.1
WP_073504179.1\|281850_282483_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	7.7e-73	66.2
WP_073504180.1\|282495_283677_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	3.5e-167	71.0
WP_073504181.1\|283689_284148_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	6.0e-59	82.9
WP_073504182.1\|284259_285261_-	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	2.0e-128	69.7
WP_073504183.1\|285527_286352_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_073504184.1\|286557_287514_+	L-lactate dehydrogenase	NA	NA	NA	NA
WP_046836749.1\|287661_288063_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_073504185.1\|288196_288760_-	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	9.0e-65	63.8
WP_073504186.1\|288756_289710_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.8e-66	83.3
WP_073504187.1\|289818_290988_+	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	5.6e-170	78.0
WP_073504188.1\|291327_293742_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	86.0
WP_073504189.1\|293761_294073_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	8.5e-33	65.0
WP_073504190.1\|294230_295490_-	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	2.2e-42	81.4

DBSCAN-SWA_3

513336 : 556591

Staphylococcus_phage(59.09%)

protease,capsid,portal,integrase,tail,terminase,head

attL 514509:514524|attR 523140:523155

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_073504329.1\|513336_514794_+\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
514509:514524	attL	NA	NA	NA	NA
WP_046836828.1\|514777_514978_+	YqgQ family protein	NA	NA	NA	NA
WP_073504330.1\|515233_515677_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_073504331.1\|515669_516494_+	N-acyl homoserine lactonase family protein	NA	NA	NA	NA
WP_073504332.1\|517174_518161_+	ROK family glucokinase	NA	NA	NA	NA
WP_046836546.1\|518160_518484_+	MTH1187 family thiamine-binding protein	NA	NA	NA	NA
WP_073504333.1\|518485_519109_+	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	1.1e-31	37.2
WP_073504334.1\|519844_521074_-\|integrase	site-specific integrase	A0A068A216	Staphylococcus_phage	1.5e-93	47.1
WP_156874665.1\|521184_521802_+	hypothetical protein	Q9MBT7	Staphylococcus_prophage	9.3e-31	38.4
WP_156874666.1\|521798_521951_-	hypothetical protein	NA	NA	NA	NA
WP_073504335.1\|522035_522743_-	hypothetical protein	Q4ZD54	Staphylococcus_phage	5.9e-21	57.6
WP_073504336.1\|522762_523302_-	hypothetical protein	A0A2H4J5W8	uncultured_Caudovirales_phage	1.1e-19	88.9
523140:523155	attR	NA	NA	NA	NA
WP_073504337.1\|523461_523953_-	hypothetical protein	A0A2H4JD66	uncultured_Caudovirales_phage	6.4e-43	51.8
WP_073504338.1\|523964_524306_-	helix-turn-helix transcriptional regulator	A0A2H4JGZ6	uncultured_Caudovirales_phage	8.2e-29	61.1
WP_073504339.1\|524502_524715_+	helix-turn-helix transcriptional regulator	A0A2H4JBA4	uncultured_Caudovirales_phage	5.1e-21	73.8
WP_073504340.1\|524775_525531_+	Rha family transcriptional regulator	I6TJS0	Staphylococcus_virus	4.8e-106	76.5
WP_073504341.1\|525578_525842_+	helix-turn-helix domain-containing protein	B7T0G2	Staphylococcus_virus	2.6e-27	69.8
WP_073504342.1\|525853_526060_+	hypothetical protein	NA	NA	NA	NA
WP_167693326.1\|526061_526238_+	hypothetical protein	NA	NA	NA	NA
WP_073504343.1\|526298_526565_+	DUF1108 family protein	A0A1W6JQ03	Staphylococcus_phage	6.4e-13	45.5
WP_073504344.1\|526558_526783_+	DUF2483 family protein	A0A2H4J5M5	uncultured_Caudovirales_phage	3.1e-29	85.9
WP_073504345.1\|526775_527393_+	DUF1071 domain-containing protein	A0A2H4JEC9	uncultured_Caudovirales_phage	8.0e-99	84.9
WP_073504346.1\|527389_527743_+	single-stranded DNA-binding protein	A0A0D4DD48	Staphylococcus_phage	4.0e-47	82.8
WP_073504347.1\|527755_528424_+	hypothetical protein	A0A1W6JQB0	Staphylococcus_phage	2.9e-102	78.7
WP_053042472.1\|528420_528660_+	helix-turn-helix transcriptional regulator	A0A1W6JNL6	Staphylococcus_phage	8.3e-12	42.1
WP_073504348.1\|528661_529444_+	replication protein	D2JGK4	Staphylococcus_phage	5.3e-55	82.8
WP_073504349.1\|529455_530241_+	ATP-binding protein	A0A1W6JPS4	Staphylococcus_phage	6.8e-103	70.1
WP_073504350.1\|530408_530621_+	hypothetical protein	NA	NA	NA	NA
WP_073504351.1\|530631_531042_+	RusA family crossover junction endodeoxyribonuclease	A0A1D6Z252	Staphylococcus_phage	1.8e-43	69.0
WP_073504352.1\|531025_531217_+	hypothetical protein	NA	NA	NA	NA
WP_073504353.1\|531218_531599_+	hypothetical protein	NA	NA	NA	NA
WP_073504354.1\|531599_531803_+	hypothetical protein	NA	NA	NA	NA
WP_073504355.1\|531786_531999_+	hypothetical protein	NA	NA	NA	NA
WP_156874667.1\|532061_532202_+	hypothetical protein	U3PE03	Staphylococcus_phage	1.2e-10	72.7
WP_167693323.1\|532188_532350_+	hypothetical protein	NA	NA	NA	NA
WP_073504357.1\|532356_532608_+	hypothetical protein	A0A2H4J4E7	uncultured_Caudovirales_phage	1.8e-12	35.2
WP_073504358.1\|532713_532899_-	hypothetical protein	NA	NA	NA	NA
WP_073504359.1\|533020_533320_+	hypothetical protein	U3PBR4	Staphylococcus_phage	4.0e-48	96.0
WP_156874676.1\|533362_533530_+	DUF1381 domain-containing protein	A0A2H4JI91	uncultured_Caudovirales_phage	1.6e-09	81.0
WP_156874668.1\|533526_533676_+	transcriptional regulator	A0A2H4JAX0	uncultured_Caudovirales_phage	7.2e-06	70.0
WP_073504360.1\|533846_534245_+	hypothetical protein	A0A1W6JQJ8	Staphylococcus_phage	7.3e-21	41.8
WP_073504361.1\|534463_534892_+	hypothetical protein	NA	NA	NA	NA
WP_073504362.1\|535187_535658_+	hypothetical protein	NA	NA	NA	NA
WP_073504363.1\|535747_536395_+	hypothetical protein	NA	NA	NA	NA
WP_073504364.1\|536473_536899_+	HNH endonuclease	A1EAE0	Streptococcus_phage	1.4e-22	47.9
WP_073504365.1\|536891_538178_+\|terminase	PBSX family phage terminase large subunit	A0A0F6N3L3	Staphylococcus_phage	5.2e-201	77.2
WP_073504366.1\|538189_539683_+\|portal	phage portal protein	A0A2H4J1M7	uncultured_Caudovirales_phage	1.1e-181	64.7
WP_073504367.1\|539688_540660_+\|capsid	minor capsid protein	A0A2H4IYR8	uncultured_Caudovirales_phage	2.1e-90	55.6
WP_167693327.1\|540671_540839_+	hypothetical protein	NA	NA	NA	NA
WP_073504368.1\|541035_541650_+	DUF4355 domain-containing protein	A0A1W6JNL4	Staphylococcus_phage	1.5e-17	50.4
WP_073504369.1\|541670_542639_+\|capsid	phage major capsid protein	A0A1W6JNT3	Staphylococcus_phage	3.9e-116	68.5
WP_073504370.1\|542711_542981_+	hypothetical protein	A0A1D6Z290	Staphylococcus_phage	1.6e-16	66.7
WP_073504371.1\|542997_543327_+\|head,tail	phage head-tail connector protein	H9A0V3	Staphylococcus_phage	1.8e-28	58.7
WP_073504372.1\|543323_543629_+	hypothetical protein	A0A1W6JNQ9	Staphylococcus_phage	1.2e-23	53.0
WP_073504373.1\|543628_543976_+	hypothetical protein	A0A1W6JNQ6	Staphylococcus_phage	5.8e-30	55.0
WP_073504374.1\|543987_544380_+	hypothetical protein	A0A1W6JNL2	Staphylococcus_phage	4.0e-27	42.4
WP_073504375.1\|544437_545019_+\|tail	phage major tail protein, TP901-1 family	A0A1W6JNU0	Staphylococcus_phage	3.2e-57	69.2
WP_073504376.1\|545153_545516_+\|tail	phage tail protein	A0A1W6JNQ1	Staphylococcus_phage	2.9e-32	56.3
WP_156874677.1\|545964_549366_+\|tail	phage tail protein	H9A0P1	Staphylococcus_phage	1.8e-14	38.8
WP_073504379.1\|549377_550349_+\|tail	phage tail protein	A0A2P1JTW0	Anoxybacillus_phage	4.5e-48	36.9
WP_073504380.1\|550363_551569_+	hypothetical protein	A0A2H4JH16	uncultured_Caudovirales_phage	1.3e-25	63.0
WP_073504381.1\|551568_551805_+	DUF2977 domain-containing protein	NA	NA	NA	NA
WP_083578823.1\|551825_554369_+	hypothetical protein	U3PDY0	Staphylococcus_phage	2.3e-160	38.8
WP_156874669.1\|554358_554505_+	hypothetical protein	NA	NA	NA	NA
WP_073504382.1\|554522_554819_+	hypothetical protein	NA	NA	NA	NA
WP_073504383.1\|554856_555168_+	hypothetical protein	A0A0D4DCQ8	Staphylococcus_phage	1.7e-20	56.1
WP_073504384.1\|555223_556591_+	CHAP domain-containing protein	Q4Z8Y9	Staphylococcus_phage	1.0e-69	35.2

DBSCAN-SWA_4

602294 : 612401

uncultured_Mediterranean_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_073504420.1\|602294_603182_+	site-specific tyrosine recombinase XerD	A0A0K2CP59	Brevibacillus_phage	1.2e-39	31.4
WP_073504421.1\|603289_603793_-	DUF309 domain-containing protein	NA	NA	NA	NA
WP_046836497.1\|603887_604622_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	3.6e-05	20.0
WP_073504422.1\|604605_605154_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	3.6e-10	31.2
WP_046836495.1\|605146_605884_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_071331599.1\|606019_606745_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.4e-46	41.3
WP_073504423.1\|606728_608495_+	HAMP domain-containing protein	A0A1V0SGX0	Hokovirus	3.9e-21	27.3
WP_073504424.1\|608920_609466_+	ECF transporter S component	NA	NA	NA	NA
WP_046836491.1\|609711_609960_-	ferredoxin	A0A127AYY7	Bacillus_phage	5.8e-16	50.7
WP_073504425.1\|610069_611035_+	hypothetical protein	NA	NA	NA	NA
WP_073504426.1\|611021_612401_+	ATP-dependent DNA helicase RecQ	M1PGQ0	Moumouvirus	2.1e-59	33.3

DBSCAN-SWA_5

1085028 : 1093498

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_073504713.1\|1085028_1085595_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.0e-28	39.2
WP_073504714.1\|1085597_1086626_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.7e-64	43.1
WP_073504715.1\|1086618_1088106_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	4.2e-45	32.2
WP_073504716.1\|1088084_1090274_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.1e-138	39.4
WP_073504717.1\|1090266_1090938_-	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_046836080.1\|1090937_1091198_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_046836079.1\|1091200_1091902_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	3.4e-45	40.3
WP_073504718.1\|1091901_1093029_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_073504719.1\|1093015_1093498_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.5e-20	44.0

DBSCAN-SWA_6

1339650 : 1359897

uncultured_Caudovirales_phage(35.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046837190.1\|1339650_1340454_-	ATP-binding cassette domain-containing protein	W6JKT0	Anomala_cuprea_entomopoxvirus	3.5e-14	26.6
WP_073504872.1\|1340450_1341410_-	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	2.7e-05	54.0
WP_046837188.1\|1341399_1342368_-	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	9.5e-139	79.8
WP_069823588.1\|1342829_1343798_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.5e-173	91.6
WP_073504873.1\|1343905_1346011_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	89.3
WP_073504874.1\|1345973_1346372_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.8e-51	75.0
WP_073504875.1\|1347086_1347974_+	DMT family transporter	NA	NA	NA	NA
WP_046837183.1\|1347988_1348489_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	8.5e-51	69.3
WP_069823583.1\|1348790_1350305_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.3e-70	36.1
WP_073504876.1\|1350541_1352050_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.4e-64	32.2
WP_107545183.1\|1352160_1353102_+	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	7.3e-11	24.7
WP_073504878.1\|1353236_1353785_-	5'(3')-deoxyribonucleotidase	A0A0A0PKY7	Bacillus_phage	1.8e-30	39.0
WP_073504879.1\|1354063_1355119_-	histidinol-phosphate transaminase	A0A0H3TLT9	Faustovirus	1.3e-16	23.7
WP_073504880.1\|1355307_1356822_-	ABC transporter permease/substrate-binding protein	NA	NA	NA	NA
WP_073504881.1\|1356821_1357784_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.4e-25	33.3
WP_046837175.1\|1358118_1359897_-	DNA helicase RecQ	M1PGQ0	Moumouvirus	6.5e-77	36.8

DBSCAN-SWA_7

1368378 : 1375777

Pandoravirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_073504886.1\|1368378_1369518_-	anthranilate synthase component I family protein	A0A0B5J984	Pandoravirus	2.7e-23	38.2
WP_073504887.1\|1369501_1370095_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	2.4e-36	42.5
WP_073504888.1\|1370349_1371021_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	1.4e-64	55.8
WP_046837164.1\|1371022_1371448_+	6-carboxytetrahydropterin synthase QueD	NA	NA	NA	NA
WP_071331414.1\|1371440_1372157_+	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	3.6e-50	43.8
WP_046837162.1\|1372451_1373048_+	hypothetical protein	NA	NA	NA	NA
WP_046837161.1\|1373108_1373363_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_073504889.1\|1373456_1374527_-	glycosyltransferase family 2 protein	A0A192Y8W7	Salmonella_phage	1.1e-60	42.9
WP_073504890.1\|1374937_1375777_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	2.3e-56	40.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage