CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP018245	Escherichia coli strain 472 chromosome, complete genome	4 crisprs	DinG,PrimPol,cas3,DEDDh,c2c9_V-U4,csa3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e	0	5	19	0
NZ_CP018246	Escherichia coli strain 472 plasmid pO157, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP018245_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018245_1

71490-71624

Orphan

Consensus_repeat	Method
TGCCGGATGCGCGTTGCTTATCCGGCCTACAAAATCGCAGCGTGTAGGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018245_1

>merge|NZ_CP018245|1|71490-71624|CRISPRCasFinder
TGCCGGATGCGCGTTGCTTATCCGGCCTACAAAATCGCAGCGTGTAGGCCAGATAAGACGCGTCAGCGTCGCATCAGGCGCTGAATGCCGGATGCGCGTTGCTTATCCGGCCTACAAAATTGCAGCGTGTAGGCC

>NZ_CP018245|1|1|71490-71624|CRISPRCasFinder
TGCCGGATGCGCGTTGCTTATCCGGCCTACAAAATCGCAGCGTGTAGGCC	AGATAAGACGCGTCAGCGTCGCATCAGGCGCTGAA
TGCCGGATGCGCGTTGCTTATCCGGCCTACAAAATTGCAGCGTGTAGGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018245.1\|WP_000868321.1\|80665_81235_+\|T3SS-effector-EspY2	unknown	unknown	unknown
NZ_CP018245.1\|WP_001117011.1\|65284_68191_-\|RNA-polymerase-associated-protein-RapA	unknown	unknown	gnl\|CDD\|235319
NZ_CP018245.1\|WP_000151715.1\|71675_73178_-\|L-arabinose-isomerase	unknown	unknown	gnl\|CDD\|179503
NZ_CP018245.1\|WP_001304001.1\|63443_64196_+\|pentapeptide-repeat-containing-protein	unknown	unknown	unknown
NZ_CP018245.1\|WP_001248768.1\|83210_83342_+\|glucose-uptake-inhibitor-SgrT	unknown	unknown	gnl\|CDD\|374203
NZ_CP018245.1\|WP_000035699.1\|68354_70706_-\|DNA-polymerase-II	unknown	unknown	gnl\|CDD\|235595
NZ_CP018245.1\|WP_001301693.1\|79310_80294_-\|thiamine-ABC-transporter-substrate-binding-subunit	unknown	unknown	gnl\|CDD\|236883
NZ_CP018245.1\|WP_001200573.1\|62333_63149_+\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512
NZ_CP018245.1\|WP_000916267.1\|77042_77741_-\|thiamine-ABC-transporter-ATP-binding-protein-ThiQ	unknown	unknown	gnl\|CDD\|182716
NZ_CP018245.1\|WP_000241259.1\|57396_58386_-\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696
NZ_CP018245.1\|WP_001148407.1\|76191_76956_+\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP018245.1\|WP_001065380.1\|56578_57400_-\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP018245.1\|WP_000888654.1\|70780_71476_-\|L-ribulose-5-phosphate-4-epimerase	unknown	unknown	gnl\|CDD\|236181
NZ_CP018245.1\|WP_000800457.1\|58385_59672_-\|peptidylprolyl-isomerase-SurA	unknown	unknown	gnl\|CDD\|236758
NZ_CP018245.1\|WP_001138626.1\|81463_83122_-\|DNA-binding-transcriptional-regulator-SgrR	unknown	unknown	gnl\|CDD\|184188
NZ_CP018245.1\|WP_000235663.1\|77724_79335_-\|thiamine/thiamine-pyrophosphate-ABC-transporter-permease-ThiP	unknown	unknown	gnl\|CDD\|181853
NZ_CP018245.1\|WP_000746183.1\|59724_62079_-\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158
NZ_CP018245.1\|WP_000951872.1\|73188_74889_-\|ribulokinase	unknown	unknown	gnl\|CDD\|235221
NZ_CP018245.1\|WP_001300811.1\|75227_76106_+\|arabinose-operon-transcriptional-regulator-AraC	unknown	unknown	gnl\|CDD\|236717
NZ_CP018245.1\|WP_000525188.1\|64613_65273_-\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	unknown	unknown	gnl\|CDD\|236659

Protein	Function_ID	Function_description	E-value
NZ_CP018245.1\|WP_001117011.1\|65284_68191_-\|RNA-polymerase-associated-protein-RapA	gnl\|CDD\|235319	PRK04914, PRK04914, RNA polymerase-associated protein RapA.	0
NZ_CP018245.1\|WP_000151715.1\|71675_73178_-\|L-arabinose-isomerase	gnl\|CDD\|179503	PRK02929, PRK02929, L-arabinose isomerase; Provisional.	0
NZ_CP018245.1\|WP_001248768.1\|83210_83342_+\|glucose-uptake-inhibitor-SgrT	gnl\|CDD\|374203	pfam15894, SgrT, Inhibitor of glucose uptake transporter SgrT.	0.00111324
NZ_CP018245.1\|WP_000035699.1\|68354_70706_-\|DNA-polymerase-II	gnl\|CDD\|235595	PRK05762, PRK05762, DNA polymerase II; Reviewed.	0
NZ_CP018245.1\|WP_001301693.1\|79310_80294_-\|thiamine-ABC-transporter-substrate-binding-subunit	gnl\|CDD\|236883	PRK11205, tbpA, thiamine transporter substrate binding subunit; Provisional.	0
NZ_CP018245.1\|WP_001200573.1\|62333_63149_+\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	1.09407e-169
NZ_CP018245.1\|WP_000916267.1\|77042_77741_-\|thiamine-ABC-transporter-ATP-binding-protein-ThiQ	gnl\|CDD\|182716	PRK10771, thiQ, thiamine ABC transporter ATP-binding protein ThiQ.	5.93317e-163
NZ_CP018245.1\|WP_000241259.1\|57396_58386_-\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0
NZ_CP018245.1\|WP_001148407.1\|76191_76956_+\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	1.79494e-49
NZ_CP018245.1\|WP_001065380.1\|56578_57400_-\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	2.27697e-148
NZ_CP018245.1\|WP_000888654.1\|70780_71476_-\|L-ribulose-5-phosphate-4-epimerase	gnl\|CDD\|236181	PRK08193, araD, L-ribulose-5-phosphate 4-epimerase AraD.	3.528e-179
NZ_CP018245.1\|WP_000800457.1\|58385_59672_-\|peptidylprolyl-isomerase-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	0
NZ_CP018245.1\|WP_001138626.1\|81463_83122_-\|DNA-binding-transcriptional-regulator-SgrR	gnl\|CDD\|184188	PRK13626, PRK13626, HTH-type transcriptional regulator SgrR.	0
NZ_CP018245.1\|WP_000235663.1\|77724_79335_-\|thiamine/thiamine-pyrophosphate-ABC-transporter-permease-ThiP	gnl\|CDD\|181853	PRK09433, thiP, thiamine transporter membrane protein; Reviewed.	0
NZ_CP018245.1\|WP_000746183.1\|59724_62079_-\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0
NZ_CP018245.1\|WP_000951872.1\|73188_74889_-\|ribulokinase	gnl\|CDD\|235221	PRK04123, PRK04123, ribulokinase; Provisional.	0
NZ_CP018245.1\|WP_001300811.1\|75227_76106_+\|arabinose-operon-transcriptional-regulator-AraC	gnl\|CDD\|236717	PRK10572, PRK10572, arabinose operon transcriptional regulator AraC.	0
NZ_CP018245.1\|WP_000525188.1\|64613_65273_-\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	gnl\|CDD\|236659	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA.	1.18143e-157

>NZ_CP018245.1|WP_000888654.1|70780_71476_-|L-ribulose-5-phosphate-4-epimerase
MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSIMTADDMVVVSIETGEVVEGAKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKHYLRKHGAKAYYGQ
>NZ_CP018245.1|WP_000035699.1|68354_70706_-|DNA-polymerase-II
MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAFIPADQVPRAQHILRGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGGVTVYEADVRPPERYLMERFITSPVWVEGDMHNGAIVNARLKPHPDYRPPLKWVSIDIETTRHGELYCIGLEGCGQRIVYMLGPENGDASALDFELEYVASRPQLLEKLNAWFANYDPDVIIGWNVVQFDLRMLQKHAERYRIPLRLGRDNSELEWREHGFKNGVFFAQAKGRLIIDGIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLKDCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLGEVPPHASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHSTEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTACRFFDPRLVSSITMRGHQIMRQTKALIEAQGYDVIYGDTDSTFVWLKGAHSEEEATKIGRALVQHVNVWWAETLQKQQLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEGDKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYFRETIDKLMAGELDARLVYRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPLQYQNRGTIKYVWTTNGPEPLDYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF
>NZ_CP018245.1|WP_001117011.1|65284_68191_-|RNA-polymerase-associated-protein-RapA
MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYARSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLNIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVEMLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDLLVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPNRFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSDSEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKVSGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVLTPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQVEFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKLSAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ
>NZ_CP018245.1|WP_000525188.1|64613_65273_-|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA
MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHSEMLTITHPAYGNSMTFKAPADF
>NZ_CP018245.1|WP_001304001.1|63443_64196_+|pentapeptide-repeat-containing-protein
MKVSVPGMPATLLNMSNNDIYKMVSGDKMDMKMNIFQRLWETLRHLFWSDKQTEAYKLLFNFVNKKAGNINASKYFTGAVNENEKEKFIHSLELFNELKTCAKNPDEMVAKGNMSWVAQTFGDIELSVTFFIENKEICTQTLQLHKGPGNLGVDLREAYLPGVDMRDCYLGLKTMKGHNKVLYLEPGWNANLDGATLDGATLDGATVDGATHLYDEVIIINKITPKKIDTEEVATKQSTAEQITDNAIIE
>NZ_CP018245.1|WP_001200573.1|62333_63149_+|co-chaperone-DjlA
MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWFANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFRVGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEELGISRAQFDQFLRMMQGGAQFGGGYQQQSGGGNWQQAQRGPTLEDACNVLGVKPTDDATTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK
>NZ_CP018245.1|WP_000746183.1|59724_62079_-|LPS-assembly-protein-LptD
MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQGDTNDLPVTINANHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVRTVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGENRYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVSIFYSPYLQLPVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEFRYLSQAGAGLMELDYLPSDKVYEDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKVSDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEPQLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTEAKLLATHYQQTNLDWYNSRNTTKLDESVNRVMPQFKVDGKMVFERDMEMLAPGYTQTLEPRAQYLYVPYRDQSDIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRIYDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISERWGLRGGIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGISQVGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWDNDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL
>NZ_CP018245.1|WP_000800457.1|58385_59672_-|peptidylprolyl-isomerase-SurA
MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIANIAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESLAQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIAHSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGESKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGSANQGGDLGWATPDIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAAQKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN
>NZ_CP018245.1|WP_000241259.1|57396_58386_-|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLTDRAAMLGLPLTLRPYSPNSPAQPQTTGTLTLLPVALRESVTAGQLAIENGHYVVETLARACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRVALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHMGTEEIDTIIPVLDELRAQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGRGEADVGSFITALNLAIKMIVNTQ
>NZ_CP018245.1|WP_001065380.1|56578_57400_-|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPFQES
>NZ_CP018245.1|WP_000151715.1|71675_73178_-|L-arabinose-isomerase
MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVKALNTEAKLPCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERIGSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDVNALVDEYESCYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAAEEKPILDVQHLGIGGKDDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR
>NZ_CP018245.1|WP_000951872.1|73188_74889_-|ribulokinase
MAIAIGLDFGSDSVRALAVDCTTGEEIATSVEWYPRWQKGQFCDAPNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAVVGIGVDSTGSTPAPIDADGNVLALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKILHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLPPASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAGQSAFGDIYAWFGRVLGWPLEQLAAQHPELKEQIDASQKQLLPALTEAWAKNPSLDHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGIAVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIPSAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVPTL
>NZ_CP018245.1|WP_001300811.1|75227_76106_+|arabinose-operon-transcriptional-regulator-AraC
MAEAQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKGYILNLTIRGQGVVKNQGREFVCRPGDILLFPPGEIHHYGRHPEAREWYHQWVYFRPRAYWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQIINAGQGEGRYSELLAINLLEQLLLRRMEAINESLHPPMDNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQLGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEFRAGCEEKVNDVAVKLS
>NZ_CP018245.1|WP_001148407.1|76191_76956_+|DedA-family-protein
MQALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAGLGALIGSGELSFWHAWLAGIVGCLLGDWISFWLGWRFKKPLHRWSFLKKNKALLDKTEHALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFITPNIIGCLLWPPFYFLPGILAGAAIDIPAGMQSGEFKWLLLATAVFLWVGGWLCWRLWRSGKATDRLSHYLSRGRLLWLTPLISAIGVVALVVLVRHPLMPVYIDILRKVVGV
>NZ_CP018245.1|WP_000916267.1|77042_77741_-|thiamine-ABC-transporter-ATP-binding-protein-ThiQ
MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNLIAGFLTPASGALTIDGVDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKLNAVQQEKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSTSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGMTNELLSGKASASALLGITG
>NZ_CP018245.1|WP_000235663.1|77724_79335_-|thiamine/thiamine-pyrophosphate-ABC-transporter-permease-ThiP
MATRRQPLIPGWLIPGVSAATLVVAVALAAFLALWWNAPQGDWSAVWQDSYLWHVVRFSFWQAFLSALLSVVPAIFLARALYRRRFPGRLALLRLCAMTLILPVLVAVFGILSVYGRQGWLASLCQSLGLEWTFSPYGLQGILLAHVFFNLPMASRLLLQALENIPGEQRQLAAQLGMRGWHFFRFVEWPWLRRQIPPVTALIFMLCFASFATVLSLGGGPQATTIELAIYQALSYDYDPARAAMLALIQMVCCLGLVLLSQRLSKAIAPGTTLLQGWRDPDDRLHSRICDTMLIVLALLLLLPPLLAVIVDGVNRQLPEVLAQPVLWQALWTSLRIALAAGVLCVVLTMMLLWSSRELRARQKMLAGQALEMSGMLILAMPGIVLATGFFLLLNNTIGLPQSADGIVIFTNALMAIPYALKVLENPMRDITARYSMLCQSLGIEGWSRLKVVELRALKRPLAQALAFACVLSIGDFGVVALFGNDDFRTLPFYLYQQIGSYRSQDGAVTALILLLLCFLLFSVIEKIPGRNVKTD
>NZ_CP018245.1|WP_001301693.1|79310_80294_-|thiamine-ABC-transporter-substrate-binding-subunit
MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPVVKKAFEADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVAADAVNVPGGWNNDIFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYQDPRTSTPGLGLLLWMQKVYGDDAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTSPAYHILEEKKDNYAAANFSEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIPTGNWMYPVANVTLPAGFEKLTKPATTLEFTPAEVAAQRQAWISEWQRAVSR
>NZ_CP018245.1|WP_000868321.1|80665_81235_+|T3SS-effector-EspY2
MKVRNPEQISIPASNTTKDPGLTNSQIIRMANLVKKTENMNIFEELWETLRNLFQSDKHSQTAARQILKDAFYFQNSDDYSKYFTGAVDGKARDKLTHWLIKFNELKEYAKDPENMAAKASLSPEGTLCVSFFIGDEAIFTLELQLKKSTRTGGIDLSNAYFNGVVICGIDCLEVDLSNAETNNSRWYD
>NZ_CP018245.1|WP_001138626.1|81463_83122_-|DNA-binding-transcriptional-regulator-SgrR
MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEENGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIADIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARTITSEKPAGLESLTLTFYQDHSEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHCIPIDWQVDAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDPE
>NZ_CP018245.1|WP_001248768.1|83210_83342_+|glucose-uptake-inhibitor-SgrT
MRQFYQHYFTATAKLCWLRWLSVPQRLTMLEELMQWEGSHSDY

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Crispr_ID: NZ_CP018245_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018245_2

3639901-3640113

TypeI-E

I-E

Consensus_repeat	Method
CGGTTTATCCCCGCTGGCGCGGGGAACAC	CRISPRCasFinder
CGGTTTATCCCCGCTGGCGCGGGGAACACA	CRT
CGGTTTATCCCCGCTGGCGCGGGGAACACA	PILER-CR

3 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e

The CRISPR arrays of NZ_CP018245_2

>merge|NZ_CP018245|2|3639901-3640113|CRISPRCasFinder,CRT,PILER-CR
CGGTTTATCCCCGCTGATGCGGGGAACACAGCGGCACGCTGGATTGAACAAATCCCTGGGCCGGTTTATCCCCGCTGGCGCGGGGAACACAAACCGAAACACACGATCAATCCGAATATGAGCGGTTTATCCCCGCTGGCGCGGGGAACACTTTGGTGACAGTTTTTGTCACTGTTTTGGTGACGGTTTATCCCCGCTGGCGCGGGGAACACA

>NZ_CP018245|2|2|3639901-3640112|CRISPRCasFinder
CGGTTTATCCCCGCTGATGCGGGGAACAC	AGCGGCACGCTGGATTGAACAAATCCCTGGGC
CGGTTTATCCCCGCTGGCGCGGGGAACAC	AAACCGAAACACACGATCAATCCGAATATGAG
CGGTTTATCCCCGCTGGCGCGGGGAACAC	TTTGGTGACAGTTTTTGTCACTGTTTTGGTGA
CGGTTTATCCCCGCTGGCGCGGGGAACAC

>NZ_CP018245|2|1|3639901-3640113|CRT
CGGTTTATCCCCGCTGATGCGGGGAACACA	GCGGCACGCTGGATTGAACAAATCCCTGGGC
CGGTTTATCCCCGCTGGCGCGGGGAACACA	AACCGAAACACACGATCAATCCGAATATGAG
CGGTTTATCCCCGCTGGCGCGGGGAACACT	TTGGTGACAGTTTTTGTCACTGTTTTGGTGA
CGGTTTATCCCCGCTGGCGCGGGGAACACA

>NZ_CP018245|2|1|3639962-3640113|PILER-CR
CGGTTTATCCCCGCTGGCGCGGGGAACACA	AACCGAAACACACGATCAATCCGAATATGAG
CGGTTTATCCCCGCTGGCGCGGGGAACACT	TTGGTGACAGTTTTTGTCACTGTTTTGGTGA
CGGTTTATCCCCGCTGGCGCGGGGAACACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018245.1\|WP_000246158.1\|3633980_3634691_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP018245.1\|WP_000029325.1\|3643874_3644411_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl\|CDD\|274193
NZ_CP018245.1\|WP_000372111.1\|3637621_3638530_-\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP018245.1\|WP_000085058.1\|3642050_3642797_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP018245.1\|WP_001173673.1\|3635587_3636193_-\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP018245.1\|WP_000039864.1\|3649373_3650108_-\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP018245.1\|WP_000517476.1\|3634709_3635021_-\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP018245.1\|WP_001290706.1\|3650181_3651894_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
NZ_CP018245.1\|WP_000144847.1\|3640498_3641422_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP018245.1\|WP_001295182.1\|3631713_3632475_-\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP018245.1\|WP_001219242.1\|3633501_3633981_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP018245.1\|WP_001090366.1\|3636192_3637620_-\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP018245.1\|WP_001084082.1\|3644407_3645970_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP018245.1\|WP_000568934.1\|3632455_3633505_-\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP018245.1\|WP_000281463.1\|3641418_3642069_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP018245.1\|WP_000490413.1\|3638781_3639819_+\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP018245.1\|WP_000956458.1\|3648957_3649110_-\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
NZ_CP018245.1\|WP_000206445.1\|3642807_3643863_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP018245.1\|WP_000063176.1\|3640208_3640502_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
NZ_CP018245.1\|WP_001246103.1\|3635214_3635538_-\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891

Protein	Function_ID	Function_description	E-value
NZ_CP018245.1\|WP_000246158.1\|3633980_3634691_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	6.38982e-120
NZ_CP018245.1\|WP_000029325.1\|3643874_3644411_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|274193	TIGR02548, CRISPR_system_Cascade_subunit_CasB, CRISPR type I-E/ECOLI-associated protein CasB/Cse2. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It was designated Cse2 originally, and renamed CasB based on its characterization in the CASCADE complex.	3.2742e-30
NZ_CP018245.1\|WP_000372111.1\|3637621_3638530_-\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP018245.1\|WP_000085058.1\|3642050_3642797_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	7.00414e-48
NZ_CP018245.1\|WP_001173673.1\|3635587_3636193_-\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148
NZ_CP018245.1\|WP_000039864.1\|3649373_3650108_-\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	5.85899e-137
NZ_CP018245.1\|WP_000517476.1\|3634709_3635021_-\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
NZ_CP018245.1\|WP_001290706.1\|3650181_3651894_-\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
NZ_CP018245.1\|WP_000144847.1\|3640498_3641422_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	7.06391e-157
NZ_CP018245.1\|WP_001295182.1\|3631713_3632475_-\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
NZ_CP018245.1\|WP_001219242.1\|3633501_3633981_-\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
NZ_CP018245.1\|WP_001090366.1\|3636192_3637620_-\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP018245.1\|WP_001084082.1\|3644407_3645970_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NZ_CP018245.1\|WP_000568934.1\|3632455_3633505_-\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NZ_CP018245.1\|WP_000281463.1\|3641418_3642069_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	5.5854e-93
NZ_CP018245.1\|WP_000490413.1\|3638781_3639819_+\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP018245.1\|WP_000956458.1\|3648957_3649110_-\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
NZ_CP018245.1\|WP_000206445.1\|3642807_3643863_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	2.45802e-155
NZ_CP018245.1\|WP_000063176.1\|3640208_3640502_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	2.35543e-65
NZ_CP018245.1\|WP_001246103.1\|3635214_3635538_-\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	3.44794e-52

>NZ_CP018245.1|WP_000490413.1|3638781_3639819_+|alkaline-phosphatase-isozyme-conversion-aminopeptidase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKNWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPQSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSVEATNWNLGNKDGYQQRAKTAAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>NZ_CP018245.1|WP_000372111.1|3637621_3638530_-|sulfate-adenylyltransferase-subunit-CysD
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHQNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>NZ_CP018245.1|WP_001090366.1|3636192_3637620_-|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRSRVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGEK
>NZ_CP018245.1|WP_001173673.1|3635587_3636193_-|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>NZ_CP018245.1|WP_001246103.1|3635214_3635538_-|DUF3561-family-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLMTVGIMFGALFMWLLG
>NZ_CP018245.1|WP_000517476.1|3634709_3635021_-|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>NZ_CP018245.1|WP_000246158.1|3633980_3634691_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVYALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGAAITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>NZ_CP018245.1|WP_001219242.1|3633501_3633981_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>NZ_CP018245.1|WP_000568934.1|3632455_3633505_-|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELVELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>NZ_CP018245.1|WP_001295182.1|3631713_3632475_-|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW
>NZ_CP018245.1|WP_000063176.1|3640208_3640502_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQITQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ
>NZ_CP018245.1|WP_000144847.1|3640498_3641422_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPPPARRSVDQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRSTKLTGKLIPLIEKVLAAGEIEPPQPAPDMLPPAIPEPETLGDSGHRGRGG
>NZ_CP018245.1|WP_000281463.1|3641418_3642069_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTGQLSPAQLLHLVDRGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQERPAESETFTIECRSFVPELRTGQQLCFNLRANPTICKAGKRHDLLMEAKRQVRGQAEGSDVWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQLRRENSRQLIQFSSVDYTGMLTVTDPGLFLQRLSQGYGKSRAFGCGLMLIKPGAEV
>NZ_CP018245.1|WP_000085058.1|3642050_3642797_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSAPDLLSAIISRRDYYTDAWWMVAVATTPDAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPLAPLLLEGNASDVLRNAYQQYQDSFRELKVSLPKLQDECWWEGEHDGLVASKILRRRDVPLNRQQWLFGERTINQGPWLSKEEPCTSQE
>NZ_CP018245.1|WP_000206445.1|3642807_3643863_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSLKRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEEKKAIEWAAKIADYLGKAKNDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEEDLALLRKDRMAVDIAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGETGFGSALFYTYICIDKDLLVENLGGDEALANQTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTEQPRSLAAAFYEPINGTRQLDVAVQRITTLRENMNTVYEQKTECASFDVMNKQGSMKDVLDFICA
>NZ_CP018245.1|WP_000029325.1|3643874_3644411_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKEEHKATLRKWHEELQEKRGERASLRRSTTVNDVCLTDGFRLFLKNRQIKWQDEPEWRITALALIAALSANVKAIDERLPFAAQLAAVMSKGRFTRLSAVKTPDELLRQLRRVVRLLNGSVNLDSLAEGVFRWCQESDDLLNHHRRHQRPTEFIRIRWALEYYQAGDVDNEQNQ
>NZ_CP018245.1|WP_001084082.1|3644407_3645970_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADLQGAAWQFLLGLLQSSFAPKDYRRWDDIWEDGLEAEKLREALLSLEHPFQFGPDSPSFMQDFEVLMGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEHVCSHCSALALFSLQLNAPSGGKGYRTGLRGGGPMTTLIELQEYQGNQQAPLWRKLWLNVMPQDEADLPLPKKFDDLVFPWLGPTRTSELAGAVVTDDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQSDALLSLMTTKNYGANYAMWQHPLTPYRVPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKSENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLNKKEGQIPKLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIEEGQDADELLGKWQKEIWLFARQDFDERVFTNPYEPVDLERVMTARKKYFTTSAEKQSAKAAREKKQEAAE
>NZ_CP018245.1|WP_000956458.1|3648957_3649110_-|type-I-toxin-antitoxin-system-Hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>NZ_CP018245.1|WP_000039864.1|3649373_3650108_-|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAQLEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKNGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
>NZ_CP018245.1|WP_001290706.1|3650181_3651894_-|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD

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Crispr_ID: NZ_CP018245_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018245_3

3665805-3665893

Orphan

I-E

Consensus_repeat	Method
GGTTTATCCCCACTGGCGCGGGGAACTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018245_3

>merge|NZ_CP018245|3|3665805-3665893|CRISPRCasFinder
GGTTTATCCCCACTGGCGCGGGGAACTCCTCGACTTTAATTTTTTCGCTGCCCGCTTTTGCGGTTTATCCCCGCTGGCGCGGGGAACTC

>NZ_CP018245|3|3|3665805-3665893|CRISPRCasFinder
GGTTTATCCCCACTGGCGCGGGGAACTC	CTCGACTTTAATTTTTTCGCTGCCCGCTTTTGC
GGTTTATCCCCGCTGGCGCGGGGAACTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018245.1\|WP_000210878.1\|3672105_3673743_-\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP018245.1\|WP_000581937.1\|3675167_3675416_-\|type-II-toxin-antitoxin-system-antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
NZ_CP018245.1\|WP_001243487.1\|3667692_3668367_+\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP018245.1\|WP_001164582.1\|3662385_3663663_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|349949
NZ_CP018245.1\|WP_000039701.1\|3663689_3665168_+\|sugar-kinase	unknown	unknown	gnl\|CDD\|212662
NZ_CP018245.1\|WP_012779383.1\|3669745_3670660_+\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP018245.1\|WP_001217990.1\|3668600_3669749_+\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP018245.1\|WP_000021347.1\|3661281_3662067_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187605
NZ_CP018245.1\|WP_000108294.1\|3654011_3654374_+\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
NZ_CP018245.1\|WP_000211937.1\|3651893_3653693_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
NZ_CP018245.1\|WP_000059304.1\|3659757_3661212_-\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NZ_CP018245.1\|WP_001199973.1\|3666232_3666904_-\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP018245.1\|WP_042909427.1\|3667058_3667679_+\|LemA-family-protein	unknown	unknown	gnl\|CDD\|224618
NZ_CP018245.1\|WP_001301644.1\|3657570_3658350_-\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl\|CDD\|224997
NZ_CP018245.1\|WP_000036723.1\|3670719_3672018_-\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP018245.1\|WP_000254738.1\|3674832_3675168_-\|endoribonuclease-MazF	unknown	unknown	gnl\|CDD\|182138
NZ_CP018245.1\|WP_001301471.1\|3654451_3655723_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182194
NZ_CP018245.1\|WP_001130278.1\|3655990_3656566_+\|glycerol-3-phosphate-responsive-antiterminator	unknown	unknown	gnl\|CDD\|224865
NZ_CP018245.1\|WP_001071648.1\|3673970_3674762_-\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP018245.1\|WP_000109503.1\|3655713_3655974_+\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|225289

Protein	Function_ID	Function_description	E-value
NZ_CP018245.1\|WP_000210878.1\|3672105_3673743_-\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP018245.1\|WP_000581937.1\|3675167_3675416_-\|type-II-toxin-antitoxin-system-antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	6.19513e-48
NZ_CP018245.1\|WP_001243487.1\|3667692_3668367_+\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	3.44494e-83
NZ_CP018245.1\|WP_001164582.1\|3662385_3663663_+\|MFS-transporter	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	7.69151e-30
NZ_CP018245.1\|WP_000039701.1\|3663689_3665168_+\|sugar-kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	1.25899e-108
NZ_CP018245.1\|WP_012779383.1\|3669745_3670660_+\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	1.30872e-104
NZ_CP018245.1\|WP_001217990.1\|3668600_3669749_+\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	5.38776e-66
NZ_CP018245.1\|WP_000021347.1\|3661281_3662067_-\|SDR-family-oxidoreductase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.24046e-138
NZ_CP018245.1\|WP_000108294.1\|3654011_3654374_+\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	1.01593e-59
NZ_CP018245.1\|WP_000211937.1\|3651893_3653693_-\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
NZ_CP018245.1\|WP_000059304.1\|3659757_3661212_-\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	4.96301e-83
NZ_CP018245.1\|WP_001199973.1\|3666232_3666904_-\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	3.98248e-155
NZ_CP018245.1\|WP_042909427.1\|3667058_3667679_+\|LemA-family-protein	gnl\|CDD\|224618	COG1704, LemA, Uncharacterized conserved protein [Function unknown].	2.13345e-77
NZ_CP018245.1\|WP_001301644.1\|3657570_3658350_-\|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	1.2806e-65
NZ_CP018245.1\|WP_000036723.1\|3670719_3672018_-\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP018245.1\|WP_000254738.1\|3674832_3675168_-\|endoribonuclease-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	1.17475e-74
NZ_CP018245.1\|WP_001301471.1\|3654451_3655723_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|182194	PRK10015, PRK10015, oxidoreductase; Provisional.	4.44674e-126
NZ_CP018245.1\|WP_001130278.1\|3655990_3656566_+\|glycerol-3-phosphate-responsive-antiterminator	gnl\|CDD\|224865	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription].	1.96043e-88
NZ_CP018245.1\|WP_001071648.1\|3673970_3674762_-\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	8.97718e-160
NZ_CP018245.1\|WP_000109503.1\|3655713_3655974_+\|ferredoxin-family-protein	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	1.18571e-41

>NZ_CP018245.1|WP_000039701.1|3663689_3665168_+|sugar-kinase
MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSWAWSEDAAVMEKFNIPRHMLFDVQMPGTVLGQITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDARAQDLSPEDLLNKKASCVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFIPIESNAKRYDAMNKGIFKALTKHTDVILKKSYEVMHGELGNADSIQSWSNA
>NZ_CP018245.1|WP_001164582.1|3662385_3663663_+|MFS-transporter
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSTSLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSVLGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTQPAAEAYRNMWLMGMAALAMVIVFTFLLFQKIRTADSAPAMASSK
>NZ_CP018245.1|WP_000021347.1|3661281_3662067_-|SDR-family-oxidoreductase
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEMIENQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASQASNYVNGHLLVVDGGYLVR
>NZ_CP018245.1|WP_000059304.1|3659757_3661212_-|FAD-binding-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREIMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVNCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK
>NZ_CP018245.1|WP_001301644.1|3657570_3658350_-|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MNILLAFKAEPDAGMLAEKEWQAAAHGNSGPDISLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFASEFVARHIAEWQRQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDAPFITLEQRTEHGLRCCRIRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAELPAMQCLQLARAEQRRGATLIDGQTVAEKAQKLWQDYLRQRMQP
>NZ_CP018245.1|WP_001130278.1|3655990_3656566_+|glycerol-3-phosphate-responsive-antiterminator
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISQIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGFFCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVCDEEDARNAINAGVVALSTTNTGVWTLAKKLL
>NZ_CP018245.1|WP_000109503.1|3655713_3655974_+|ferredoxin-family-protein
MSVARNLWRAADAPHIVPADSVERQMVQRLINACPVGLFSLTPEGDLRVDYHGCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG
>NZ_CP018245.1|WP_001301471.1|3654451_3655723_+|FAD-dependent-oxidoreductase
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLTPDCATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQSRVPASELLARFKTHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDTALTGAQAAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPVLLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLLWRHLRRHGLWNLAGDVIRSVRCL
>NZ_CP018245.1|WP_000108294.1|3654011_3654374_+|6-carboxytetrahydropterin-synthase-QueD
MSTTLFKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCIYRGE
>NZ_CP018245.1|WP_000211937.1|3651893_3653693_-|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVLNQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLTAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSVATGVVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQEEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY
>NZ_CP018245.1|WP_001199973.1|3666232_3666904_-|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP018245.1|WP_042909427.1|3667058_3667679_+|LemA-family-protein
MKRDLNTLRIFIVIIFIFNLSGCGYNDIQTYDEQVNASWSEVLNQYQRRADLIPNLVASIKGYSSHERDVLEAVTLARSQANRASSDLQQTPGDEQKLQAWQQAQAQVTRTLGQLTIISERYPELKSQELYQNLMVQLEGSENRIAVARGRYIKAIEQYNVTIRKFPAVLTAKVMDYTPKKNYLPDDVAAVSKAPTIDFSQNANAH
>NZ_CP018245.1|WP_001243487.1|3667692_3668367_+|YgcG-family-protein
MRNFIFLMAFFCSSVFATQIPVPESPKYVNDLTGTLTNSEVNTLTNQIKALTQKNYAQLVVLVVETTGDETIEQYATRVFDSWKPGDKDRDDGVLLLVAWQDHTVRIEIGYGLEGIITDAQSGKIIRNSIIPAFKKGDLAGGLQKGISDIESRLTGNNLATITPTDHPLPFSGWWALLVWAIVLTFISARGYIKTLGVICFAAIVLAFVLPIAGFSGSWGVLAT
>NZ_CP018245.1|WP_001217990.1|3668600_3669749_+|YgcG-family-protein
MRIFLLLLMLCGFQVFAERLPSVTDLTGTLTTEEQTALTQQLQTLEQQNHFQVAVLVTPTTGGKNIKLAASQRYGVYHWKPVGEKRYGEGILILVVWPEGLASMKIGHGLEEMLPPEQAAQIVRYHMQPEFEKNNLFAGLTGGIESIAQFTHIKANLSPLDALANHLFANPQRSLPCLAWTLLMIVAIVVLWLFASRPRRGIWMISMITPMVWFFSFQDDVIIRRVSVVCFSLLLATTCKQRLAVVFNMCRVFPMMLTPKNKNAKVKKQKKTPQVRESGRNSLFVVMLIIIVGWCLVFASNKDIAFISTIIGLIDHFIGPITIAGIVLLIIVAKFTGNLKLGSGEKSNRKTGNRNAHSRSSSRNSFRGGGGSSGGGGSSVRW
>NZ_CP018245.1|WP_012779383.1|3669745_3670660_+|YgcG-family-protein
MIVMRLIFILFTLWCLPGLAQQIAVPELRQQVTDITGTLSTSEQQSLTQQLQDITHKTRAQVAVLVVPSTGDDSIEQYATRVFDSWKLGDKQRNDGILLLVAWEDHAVRIEVGYGLEGVVTDLQAAKIIRDILIPAFKSDDLMGGLTLASENIGALLLNGELPEDRGDYYSINPPIPLSLAVIILLAVLSYFIVFTDPSNLPWITLTGAIYGMVFLYVAEPGPWTNLIVACGMLTPFAIVPLVIFWLIVNKKLRAKYKKLSKDRASRKGSSSSSSGGGSSGGGSGGGFSGGGGSSGGGGASGRW
>NZ_CP018245.1|WP_000036723.1|3670719_3672018_-|phosphopyruvate-hydratase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP018245.1|WP_000210878.1|3672105_3673743_-|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>NZ_CP018245.1|WP_001071648.1|3673970_3674762_-|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>NZ_CP018245.1|WP_000254738.1|3674832_3675168_-|endoribonuclease-MazF
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>NZ_CP018245.1|WP_000581937.1|3675167_3675416_-|type-II-toxin-antitoxin-system-antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW

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Crispr_ID: NZ_CP018245_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP018245_4

5354947-5355096

Orphan

Consensus_repeat	Method
CGCGTCTTATCAGGCCTACGAGTTCGGTGCTGTGTAGGTCGGATAAGGCGTTCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP018245_4

>merge|NZ_CP018245|4|5354947-5355096|CRISPRCasFinder
CGCGTCTTATCAGGCCTACGAGTTCGGTGCTGTGTAGGTCGGATAAGGCGTTCATGCCGCATCCGACAATAACAGCATTGCCTGATGCGACGCTTGCGCGTCTTATCAGGCCTACGAGTTCAGTGCTGTGTAGGTCGGATAAGGCGTTCA

>NZ_CP018245|4|4|5354947-5355096|CRISPRCasFinder
CGCGTCTTATCAGGCCTACGAGTTCGGTGCTGTGTAGGTCGGATAAGGCGTTCA	TGCCGCATCCGACAATAACAGCATTGCCTGATGCGACGCTTG
CGCGTCTTATCAGGCCTACGAGTTCAGTGCTGTGTAGGTCGGATAAGGCGTTCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP018245.1\|WP_162829202.1\|5364424_5365638_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP018245.1\|WP_000002953.1\|5349071_5349488_+\|ribonuclease-E-inhibitor-RraB	unknown	unknown	gnl\|CDD\|236876
NZ_CP018245.1\|WP_000079623.1\|5350229_5351426_+\|DUF898-domain-containing-protein	unknown	unknown	gnl\|CDD\|226719
NZ_CP018245.1\|WP_072617070.1\|5346112_5347849_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP018245.1\|WP_001261097.1\|5366319_5366652_-\|NIPSNAP-family-protein	unknown	unknown	gnl\|CDD\|311781
NZ_CP018245.1\|WP_001295681.1\|5358010_5359093_+\|LPS-export-ABC-transporter-permease-LptG	unknown	unknown	gnl\|CDD\|237900
NZ_CP018245.1\|WP_000397144.1\|5355132_5356644_-\|leucyl-aminopeptidase	unknown	unknown	gnl\|CDD\|234863
NZ_CP018245.1\|WP_000012925.1\|5347905_5348910_-\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|179587
NZ_CP018245.1\|WP_000416407.1\|5351480_5354336_-\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NZ_CP018245.1\|WP_000500712.1\|5344015_5344729_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|183714
NZ_CP018245.1\|WP_000083142.1\|5362275_5364225_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271184
NZ_CP018245.1\|WP_000584114.1\|5356910_5358011_+\|LPS-export-ABC-transporter-permease-LptF	unknown	unknown	gnl\|CDD\|185075
NZ_CP018245.1\|WP_001301967.1\|5360885_5361905_-\|NADPH-dependent-aldehyde-reductase-Ahr	unknown	unknown	gnl\|CDD\|176186
NZ_CP018245.1\|WP_001046858.1\|5365820_5366198_-\|DUF4160-domain-containing-protein	unknown	unknown	gnl\|CDD\|379344
NZ_CP018245.1\|WP_001294533.1\|5359253_5360756_-\|DUF853-domain-containing-protein	unknown	unknown	gnl\|CDD\|283518
NZ_CP018245.1\|WP_000786399.1\|5354335_5354779_-\|DNA-polymerase-III-subunit-chi	unknown	unknown	gnl\|CDD\|235581
NZ_CP018245.1\|WP_000588536.1\|5367654_5368122_-\|DUF1643-domain-containing-protein	unknown	unknown	gnl\|CDD\|226783
NZ_CP018245.1\|WP_000583470.1\|5345537_5345990_+\|toxin-antitoxin-biofilm-protein-TabA	unknown	unknown	gnl\|CDD\|225345
NZ_CP018245.1\|WP_001059397.1\|5349533_5350037_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP018245.1\|WP_000256678.1\|5344799_5345393_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102

Protein	Function_ID	Function_description	E-value
NZ_CP018245.1\|WP_162829202.1\|5364424_5365638_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.70413e-158
NZ_CP018245.1\|WP_000002953.1\|5349071_5349488_+\|ribonuclease-E-inhibitor-RraB	gnl\|CDD\|236876	PRK11191, PRK11191, ribonuclease E inhibitor RraB.	4.50628e-69
NZ_CP018245.1\|WP_000079623.1\|5350229_5351426_+\|DUF898-domain-containing-protein	gnl\|CDD\|226719	COG4269, COG4269, Predicted membrane protein [Function unknown].	5.35185e-152
NZ_CP018245.1\|WP_000083142.1\|5362275_5364225_+\|site-specific-integrase	gnl\|CDD\|271184	cd01184, INT_C_like_1, Uncharacterized site-specific tyrosine recombinase, C-terminal catalytic domain. Tyrosine recombinase (integrase) belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain containing six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	3.00603e-64
NZ_CP018245.1\|WP_001261097.1\|5366319_5366652_-\|NIPSNAP-family-protein	gnl\|CDD\|311781	pfam07978, NIPSNAP, NIPSNAP. Members of this family include many hypothetical proteins. It also includes members of the NIPSNAP family which have putative roles in vesicular transport. This domain is often found in duplicate.	3.32232e-05
NZ_CP018245.1\|WP_001295681.1\|5358010_5359093_+\|LPS-export-ABC-transporter-permease-LptG	gnl\|CDD\|237900	PRK15071, PRK15071, lipopolysaccharide ABC transporter permease; Provisional.	0
NZ_CP018245.1\|WP_000397144.1\|5355132_5356644_-\|leucyl-aminopeptidase	gnl\|CDD\|234863	PRK00913, PRK00913, multifunctional aminopeptidase A; Provisional.	0
NZ_CP018245.1\|WP_000012925.1\|5347905_5348910_-\|ornithine-carbamoyltransferase	gnl\|CDD\|179587	PRK03515, PRK03515, ornithine carbamoyltransferase subunit I; Provisional.	0
NZ_CP018245.1\|WP_000416407.1\|5351480_5354336_-\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_CP018245.1\|WP_000500712.1\|5344015_5344729_-\|SDR-family-oxidoreductase	gnl\|CDD\|183714	PRK12742, PRK12742, SDR family oxidoreductase.	2.19644e-150
NZ_CP018245.1\|WP_000588536.1\|5367654_5368122_-\|DUF1643-domain-containing-protein	gnl\|CDD\|226783	COG4333, COG4333, Uncharacterized protein conserved in bacteria [Function unknown].	1.3168e-96
NZ_CP018245.1\|WP_000584114.1\|5356910_5358011_+\|LPS-export-ABC-transporter-permease-LptF	gnl\|CDD\|185075	PRK15120, PRK15120, lipopolysaccharide ABC transporter permease LptF; Provisional.	0
NZ_CP018245.1\|WP_001301967.1\|5360885_5361905_-\|NADPH-dependent-aldehyde-reductase-Ahr	gnl\|CDD\|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	5.44918e-169
NZ_CP018245.1\|WP_001046858.1\|5365820_5366198_-\|DUF4160-domain-containing-protein	gnl\|CDD\|379344	pfam13711, DUF4160, Domain of unknown function (DUF4160).	8.71141e-09
NZ_CP018245.1\|WP_001294533.1\|5359253_5360756_-\|DUF853-domain-containing-protein	gnl\|CDD\|283518	pfam05872, DUF853, Bacterial protein of unknown function (DUF853). This family consists of several bacterial proteins of unknown function. BMEI1370 is thought to be an ATPase.	0
NZ_CP018245.1\|WP_000786399.1\|5354335_5354779_-\|DNA-polymerase-III-subunit-chi	gnl\|CDD\|235581	PRK05728, PRK05728, DNA polymerase III subunit chi; Validated.	5.53743e-66
NZ_CP018245.1\|WP_000583470.1\|5345537_5345990_+\|toxin-antitoxin-biofilm-protein-TabA	gnl\|CDD\|225345	COG2731, EbgC, Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism].	3.50239e-70
NZ_CP018245.1\|WP_001059397.1\|5349533_5350037_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.52162e-19
NZ_CP018245.1\|WP_000256678.1\|5344799_5345393_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	9.63528e-10

>NZ_CP018245.1|WP_000786399.1|5354335_5354779_-|DNA-polymerase-III-subunit-chi
MKNATFYLLDNDTTVDGLSAVEQLVCEIAAERWRSGKRVLIACEDEKQAYRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRSSSPRDILISLRTSFADFATAFTEVVDFVPYEDSLKQLARERYKAYRVAGFNLNTATWK
>NZ_CP018245.1|WP_000416407.1|5351480_5354336_-|valine--tRNA-ligase
MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEEEVRKENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVLPADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEGFVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL
>NZ_CP018245.1|WP_000079623.1|5350229_5351426_+|DUF898-domain-containing-protein
MAQVINEMDVPSHSFVFHGTGERYFLICVVNVLLTIITLGIYLPWALMKCKRYLYANMEVNGQRFSYGITGGNVFFSCLVFVFFYFAILMTVSADMPLIGCVLTLSLLVLLIFMAAKGLRYQALMTSLNGVRFSFNCSMKGVWWVTFFLPILMAIGMGTVFFISTKMLHANSSSSVIVSVVLMAIVGIVSIGIFNGTLYSLVMSFLWSNTSFGIHRFKVKLDTAYCIKYAILAFLALLPFLAVAGYIIFDQILNAYDSSVYANDDIENLQQFMEMQRKMIIAQLIYYFGIAVSTSYLTVSLRNHFMSNLSLNDGRIRFRSTLTYHGMLYRMCALVVISGITGGLAYPLLKIWMIDWQAKNTYLLGDLDDLPLINKEEQPDKGFLASISRGIMPSLPFL
>NZ_CP018245.1|WP_001059397.1|5349533_5350037_-|GNAT-family-N-acetyltransferase
MNNIAPQSPVMRRLTLQDNPAIARVIRQVSAEYGLTADKGYTVADPNLDELYQVYSQPGHAYWVVEYEGEVVGGGGIAPLAGSESDICELQKMYFLPAIRGKGLAKKLALKAMEEAREMGFKRCYLETTAFLKEAIGLYEHLGFQHIDYALGCTGHVDCEVRMLREL
>NZ_CP018245.1|WP_000002953.1|5349071_5349488_+|ribonuclease-E-inhibitor-RraB
MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLETLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAEKFDVEYDGWGTYFEDPNGEDGDDEDFVDEDDDGVRH
>NZ_CP018245.1|WP_000012925.1|5347905_5348910_-|ornithine-carbamoyltransferase
MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKPFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTEDVAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNSKMMQLTGNPEVKFLHCLPAFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSK
>NZ_CP018245.1|WP_072617070.1|5346112_5347849_+|hypothetical-protein
MSKISDLNYSQHITLADNFKQKSEVLNTWRVGMNNFARNAGGQDNTRNILNPKTFLEFLVKIFTLGYVDFSKRSNEAGRNMMAHIESSSYIKNNDGSEIMKFVMNNPEGERADSPKVIIEISLSTITTMGTRQGHTAIIFPQPDGSTNRYERKSFERKDESSLHLITNKVLACYQREANKEIARLLNNHQKLNNLQKLNNLQKLNNIQKLNNIQELNNSQELNNSQELNNSQDLKNSQVSCKGSVDFTITDLLEKSLNNALLAIRNEHLLLMPHVCSESISYLLGENGILEEIDKLYELNDHGIDNDKEGNNEINDIMINLSHILIESLDDAKVNLTPVIHSMLMIFLELPYNNDVKILEWCFNKSMQYFDDSAKIEHACSVINHINFRRDQSKVAETLFFNLDKEPYKNSPELQELIWKKLVVYVNDFNLSNREKTYLIQRIFNNVESLFNKVPVSILVNDIFMNDFFMKNTEMINWYFPRLLKSYEDEKIYFDKLGYNFNNKESNEEIMKNQPKDVIEEKLNNELKLRFRMMQTILKSEVNVSPFIDQQRLNTLNPPENLRIAIEKFGWKKKTITA
>NZ_CP018245.1|WP_000583470.1|5345537_5345990_+|toxin-antitoxin-biofilm-protein-TabA
MIIGNIHNLQPWLPQELRQAIEHIKAHVTAETPKGKHDIEGNRLFYLISEDMTEPYEARRAEYHARYLDIQIVLKGQEGMTFSTQPAGTPDTDWLADKDIAFLPEGVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKMLMA
>NZ_CP018245.1|WP_000256678.1|5344799_5345393_+|TetR/AcrR-family-transcriptional-regulator
MVTKKQSRVPGRPRRFAPEQAVSAAKVLFHQKGFDAVSVAEVTDYLGINPPSLYAAFGSKAGLFSRVLNEYVGTEAIPLVDILRDDRPVGECLAEVLKEAARRYSQNGGCAGCMVLEGIHSHDPQARDIAVQYYHAAETAIYDYIARLHPQSAQCVTDFMSTVMSGLSAKAREGHSLEQLCATAALAGEAIKTILKE
>NZ_CP018245.1|WP_000500712.1|5344015_5344729_-|SDR-family-oxidoreductase
MGAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAERLAQETGATAVFTDSADRDAVIDVVRKSGALDILVVNAGIGVFGDALELNADDIDRLFKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGLARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHSFMAIKRHGQPEEVAGMVAWLAGPEASFVTGAMHTIDGAFGA
>NZ_CP018245.1|WP_000397144.1|5355132_5356644_-|leucyl-aminopeptidase
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE
>NZ_CP018245.1|WP_000584114.1|5356910_5358011_+|LPS-export-ABC-transporter-permease-LptF
MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIPANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAAMILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLFIESVDGSDFKDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNQGTRFEGTALLRDFRITDFQDYQAIIGHQAVALDPNDTDQMDMRTLWNTDTDRARAELNWRITLVFTVFMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNGGKGKLDPTLWMWTVNLIYLALAIVLNLWDTVPVRRLRASFSRKGAV
>NZ_CP018245.1|WP_001295681.1|5358010_5359093_+|LPS-export-ABC-transporter-permease-LptG
MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQGSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQVALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNFVYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPKQITGSQTVSGTWKTNLTPDKLGVVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMWSKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYGIPPIIGALLPSASFFLISLWLLMRKS
>NZ_CP018245.1|WP_001294533.1|5359253_5360756_-|DUF853-domain-containing-protein
MSEPLLIARTPDTELFLLPGMANRHGLITGATGTGKTVTLQKLAESLSEIGVPVFMADVKGDLTGIAQAGTASEKLLARLKNIDVNDWQPHANPVVVWDIFGEKGHSVRATVSDLGPLLLARLLNLNDVQSGVLNIIFRIADDQGLLLLDFKDLRAITQYIGDNAKSFQNQYGNISSASVGAIQRGLLSLEQQGAAHFFGEPMLDIKDWMRTDANGKGVINILSAEKLYQMPKLYAASLLWMLSELYEQLPEAGDLEKPKLVFFFDEAHLLFNDAPQVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQHALRAFTPKDQKAVKAAAQTMRANPAFDTEKAIQELGTGEALISFLDAKGSPSVVERAMVIAPCSRMGPVTEDERNGLINHSPVYGKYEDEVDRESAYEMLQKGFQASTEQQNNPPAKGKEVAVDDGILGGLKDILFGTTGPRGGKKDGVVQTMAKSAARQVTNQIVRGMLGSLLGGRRR
>NZ_CP018245.1|WP_001301967.1|5360885_5361905_-|NADPH-dependent-aldehyde-reductase-Ahr
MSMIKSYAAKEAGGELEVYEYDPGELRPQDVEVQVDYCGICHSDLSMIDNEWGFSQYPLVAGHEVIGRVVALGSAAQDKGLQVGQRVGIGWTARSCGHCDACISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIESAGPLLCGGITVFKPLLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVNSRDPQALKALSGQFDLIINTVNVSLDWQPYFEALTYGGNFHTVGAVLTPLPVPAFTLIAGDRSVSGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDAIKHVRDGKARYRVVLKADF
>NZ_CP018245.1|WP_000083142.1|5362275_5364225_+|site-specific-integrase
MSQRYKLYRRTSGIYVVRISVPQRFRRYAGQCEIHTSTGTHDLHEAKQKSALLLAVWYQTLQEYEQLDYRTLSDCAPLLAGEGMISLSNFAQSIELPISQLIREVVNRNLPVFWLATGQFGFYVDEFNAVEREPGAKREKQSDDEKDQPKEVIILNSAFELGIESFANGYLRPFNPRHTLDCLLSAGVSEGEAAFRTSGDNQSGGWFFDLPGVDITADSLLISKVHAEGLRLTWLVKTTPPAVSIHPAVPLVAPVIANEYVHRKHYNENLSWLREEYLKHRRKGKVSEAALRDIRYYFDLMIEVMGDIQLEDFDRDFLRAYESKLRTIPANRNLMKGKHGVKTLDELIAKAAECGDKLMTEESVKKYINGLYGAMEWAVDDGKFLKSPCDNFFPPDDKGEREQDHTDIFEPHEIKAIFSQPWFVAGTVERNAQGRFHQYCPFHYWAPLLGLMTGARVNEIAQLMLDDVLADDGVYYLNLESDSENGKKLKNANSRRKIPVHSTLIELGFIEYVDALKAAGYDRLFPELKPHKTKGYGRPVSAWFNESLLAGRLKLERDRSKSFHSFRHSVSTLLKEKGVSSELRGQLLGHVRGKTETEVRYSKDLKPVHMVEVVEKIDFSLPEIARFNIPDGLDAVRDALRRKRGKQTG
>NZ_CP018245.1|WP_162829202.1|5364424_5365638_+|IS3-family-transposase
MTKNTRFSPEVRQRAIRMVLESQDEYDSQWAAICSIAPKIGCTPETLRVWVRQHERDTGGGDGGLTSAERQRLKELERENRELRRSNDILRQASAYFGEGGVRPPLEKMMPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQHDDWLKREIQRVYDENHQVYGVRKVWRQLLREGIRVARCTVARLMAVMGLAGVLRGKKVRTTISRKAVAAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGYIVGWRVSSSMETTFVLDALEQALWARRPSGTIHHSDKGSQYVSLAYTERLKEAGLLASTGSTGDSYDNAMAESINGLYKAEVIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHTPPAEAEKAYYASIGNDDLAA
>NZ_CP018245.1|WP_001046858.1|5365820_5366198_-|DUF4160-domain-containing-protein
MNLDEEFYELQKLFAQKDLLTEKRRSSGGGFMEILLVKRQNMKIKIYQEKGHQLPHIHIDYGKQAHAASYAIQSGDRIEGDLPKKYDSDVSSWLGRNRDKILEIWNALQAGAPYEPLIAELTGGV
>NZ_CP018245.1|WP_001261097.1|5366319_5366652_-|NIPSNAP-family-protein
MRTVEILQYTLRKGSGAAFHAIMQEISVPLHQSHGIDVVSFGNSLDDLDCYYLIRAFDSAKSMTAVLDAFYASADWRSGPREDIIGSIENCIKTVISLPSESVKGLRMQS
>NZ_CP018245.1|WP_000588536.1|5367654_5368122_-|DUF1643-domain-containing-protein
MIKDAIFSPCGKYRYSLSRVWDESKPYTLFIGLNPSYADAEKDDRTLSRCISFAKSWGYGGVYMANLFAFVHTQRHEMMKASDPIGKDNDSHLIRLVSGAGLVVAAWGNEGRHLKRSTTVRQLLPESTMCFVLNATGEPKHPLYMKNDSVLIPLG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP018245_2	2.3\|3640052\|32\|NZ_CP018245\|CRISPRCasFinder	3640052-3640083	32	MK047640	Phage NV18, complete genome	15645-15676	1	0.969
NZ_CP018245_2	2.6\|3640053\|31\|NZ_CP018245\|CRT,PILER-CR	3640053-3640083	31	MK047640	Phage NV18, complete genome	15646-15676	1	0.968
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	101196-101230	2	0.943
NZ_CP018245_2	2.3\|3640052\|32\|NZ_CP018245\|CRISPRCasFinder	3640052-3640083	32	MF417881	Uncultured Caudovirales phage clone 7AX_3, partial genome	2718-2749	2	0.938
NZ_CP018245_2	2.6\|3640053\|31\|NZ_CP018245\|CRT,PILER-CR	3640053-3640083	31	MF417881	Uncultured Caudovirales phage clone 7AX_3, partial genome	2718-2748	2	0.935
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	165464-165498	3	0.914
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP048307	Escherichia coli strain 9 plasmid p009_C, complete sequence	14239-14273	5	0.857
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP044308	Escherichia coli strain C27A plasmid pC27A-3, complete sequence	56080-56114	5	0.857
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	6804-6838	6	0.829
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	208981-209015	6	0.829
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	219475-219509	6	0.829
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	210309-210343	6	0.829
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	191264-191298	6	0.829
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP010208	Escherichia coli strain M11 plasmid B, complete sequence	30177-30211	6	0.829
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	MT230312	Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence	170-204	6	0.829
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_AP023209	Escherichia coli strain TUM18781 plasmid pMTY18781-4, complete sequence	88-122	6	0.829
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	87137-87171	7	0.8
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	138033-138067	7	0.8
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	43-77	7	0.8
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	3372-3406	7	0.8
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	208887-208921	7	0.8
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	42-76	7	0.8
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	3371-3405	7	0.8
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	219381-219415	7	0.8
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	42-76	7	0.8
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	3371-3405	7	0.8
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	210215-210249	7	0.8
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	42-76	7	0.8
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	3371-3405	7	0.8
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	191170-191204	7	0.8
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP010208	Escherichia coli strain M11 plasmid B, complete sequence	27246-27280	7	0.8
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	18350-18384	7	0.8
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	15018-15052	7	0.8
NZ_CP018245_2	2.4\|3639931\|31\|NZ_CP018245\|CRT	3639931-3639961	31	NC_015512	Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY02, complete sequence	90200-90230	7	0.774
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	61916-61950	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4114-4148	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229148-229182	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229249-229283	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229350-229384	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229451-229485	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	203852-203886	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	204038-204072	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	204131-204165	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4113-4147	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239642-239676	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239743-239777	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239844-239878	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239945-239979	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	214346-214380	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	214532-214566	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	214625-214659	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4113-4147	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230554-230588	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230655-230689	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230756-230790	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230857-230891	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	205180-205214	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	205366-205400	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	205459-205493	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4113-4147	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211524-211558	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211625-211659	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211726-211760	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211827-211861	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	186135-186169	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	186321-186355	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	186414-186448	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	14272-14306	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP044147	Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2	6744-6778	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP044147	Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2	7392-7426	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	CP044351	Escherichia coli strain 194195 plasmid p194195_1, complete sequence	83590-83624	8	0.771
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	CP044351	Escherichia coli strain 194195 plasmid p194195_1, complete sequence	84216-84250	8	0.771
NZ_CP018245_2	2.1\|3639930\|32\|NZ_CP018245\|CRISPRCasFinder	3639930-3639961	32	NC_015512	Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY02, complete sequence	90200-90231	8	0.75
NZ_CP018245_2	2.6\|3640053\|31\|NZ_CP018245\|CRT,PILER-CR	3640053-3640083	31	NC_011370	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG203, complete sequence	102901-102931	8	0.742
NZ_CP018245_2	2.6\|3640053\|31\|NZ_CP018245\|CRT,PILER-CR	3640053-3640083	31	NZ_CP032697	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525a, complete sequence	313484-313514	8	0.742
NZ_CP018245_2	2.6\|3640053\|31\|NZ_CP018245\|CRT,PILER-CR	3640053-3640083	31	NZ_CP049249	Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed3, complete sequence	984473-984503	8	0.742
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	386558-386592	9	0.743
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4013-4047	9	0.743
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4012-4046	9	0.743
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4012-4046	9	0.743
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4012-4046	9	0.743
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP044308	Escherichia coli strain C27A plasmid pC27A-3, complete sequence	13988-14022	9	0.743
NZ_CP018245_1	1.1\|71540\|35\|NZ_CP018245\|CRISPRCasFinder	71540-71574	35	NZ_CP019246	Escherichia coli strain Combat13F7 plasmid pCombat13F7-1, complete sequence	41415-41449	9	0.743
NZ_CP018245_2	2.3\|3640052\|32\|NZ_CP018245\|CRISPRCasFinder	3640052-3640083	32	NC_011370	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG203, complete sequence	102900-102931	9	0.719
NZ_CP018245_2	2.3\|3640052\|32\|NZ_CP018245\|CRISPRCasFinder	3640052-3640083	32	NZ_CP032697	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525a, complete sequence	313483-313514	9	0.719
NZ_CP018245_2	2.3\|3640052\|32\|NZ_CP018245\|CRISPRCasFinder	3640052-3640083	32	NZ_CP049249	Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed3, complete sequence	984472-984503	9	0.719

1. spacer 2.3|3640052|32|NZ_CP018245|CRISPRCasFinder matches to MK047640 (Phage NV18, complete genome) position: , mismatch: 1, identity: 0.969

tttggtgacagtttttgtcactgttttggtga	CRISPR spacer
tttggtgacactttttgtcactgttttggtga	Protospacer
********** *********************

2. spacer 2.6|3640053|31|NZ_CP018245|CRT,PILER-CR matches to MK047640 (Phage NV18, complete genome) position: , mismatch: 1, identity: 0.968

ttggtgacagtttttgtcactgttttggtga	CRISPR spacer
ttggtgacactttttgtcactgttttggtga	Protospacer
********* *********************

3. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 2, identity: 0.943

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcgctgaa	Protospacer
 ***********.**********************

4. spacer 2.3|3640052|32|NZ_CP018245|CRISPRCasFinder matches to MF417881 (Uncultured Caudovirales phage clone 7AX_3, partial genome) position: , mismatch: 2, identity: 0.938

tttggtgacagtttttgtcactgttttggtga	CRISPR spacer
tttggtgacactttttgtcactgatttggtga	Protospacer
********** ************ ********

5. spacer 2.6|3640053|31|NZ_CP018245|CRT,PILER-CR matches to MF417881 (Uncultured Caudovirales phage clone 7AX_3, partial genome) position: , mismatch: 2, identity: 0.935

ttggtgacagtttttgtcactgttttggtga	CRISPR spacer
ttggtgacactttttgtcactgatttggtga	Protospacer
********* ************ ********

6. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 3, identity: 0.914

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
agataagacgcgtcagcgtcgcatcaggcgttaca	Protospacer
******************************.*. *

7. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP048307 (Escherichia coli strain 9 plasmid p009_C, complete sequence) position: , mismatch: 5, identity: 0.857

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgacagcggcgcatcaggcgctggt	Protospacer
 *********** ***** **************.

8. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP044308 (Escherichia coli strain C27A plasmid pC27A-3, complete sequence) position: , mismatch: 5, identity: 0.857

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
cgctaagacgcgccagcgtcgcatcaggcgttgag	Protospacer
 * *********.*****************.***.

9. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 6, identity: 0.829

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
agataagacgcgtcagcgtcgcatctggcataaac	Protospacer
************************* ***.. .*

10. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 6, identity: 0.829

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatctga	Protospacer
 ****************************... .*

11. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 6, identity: 0.829

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatctga	Protospacer
 ****************************... .*

12. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 6, identity: 0.829

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatctga	Protospacer
 ****************************... .*

13. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 6, identity: 0.829

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatctga	Protospacer
 ****************************... .*

14. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP010208 (Escherichia coli strain M11 plasmid B, complete sequence) position: , mismatch: 6, identity: 0.829

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatcaga	Protospacer
 ****************************.....*

15. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to MT230312 (Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence) position: , mismatch: 6, identity: 0.829

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcttcaat	Protospacer
 **************************** ...*

16. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_AP023209 (Escherichia coli strain TUM18781 plasmid pMTY18781-4, complete sequence) position: , mismatch: 6, identity: 0.829

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatcggc	Protospacer
 ****************************...*.

17. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcggcagcgtcgcatcaggcatcgtg	Protospacer
 *********** ****************...* .

18. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcattagcgtcgcatcaggcagcgca	Protospacer
 **********.*.***************. .* *

19. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatcagc	Protospacer
 ****************************.....

20. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcacctgc	Protospacer
 ***********.****************.*. .

21. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataaaacgcgtcagcgtcgcatcaggcatcggc	Protospacer
 *****.**********************...*.

22. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatcagc	Protospacer
 ****************************.....

23. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcacctgc	Protospacer
 ***********.****************.*. .

24. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataaaacgcgtcagcgtcgcatcaggcatcggc	Protospacer
 *****.**********************...*.

25. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatcagc	Protospacer
 ****************************.....

26. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcacctgc	Protospacer
 ***********.****************.*. .

27. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataaaacgcgtcagcgtcgcatcaggcatcggc	Protospacer
 *****.**********************...*.

28. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatcagc	Protospacer
 ****************************.....

29. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcacctgc	Protospacer
 ***********.****************.*. .

30. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataaaacgcgtcagcgtcgcatcaggcatcggc	Protospacer
 *****.**********************...*.

31. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP010208 (Escherichia coli strain M11 plasmid B, complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtctgcgtcgcatctggcaccggt	Protospacer
 ************* ********** ***.*.*.

32. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgcatcaggcatcagc	Protospacer
 ****************************.....

33. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 7, identity: 0.8

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcacctgg	Protospacer
 ***********.****************.*. ..

34. spacer 2.4|3639931|31|NZ_CP018245|CRT matches to NC_015512 (Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY02, complete sequence) position: , mismatch: 7, identity: 0.774

gcggcacgctggattgaacaaat---ccctgggc	CRISPR spacer
gcggcacgatgggttgaacaaatggactttg---	Protospacer
******** ***.**********   *..**

35. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
agataagacgcgccagcgtcgcatctggcatctgc	Protospacer
************.************ ***... .

36. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcatctgc	Protospacer
 ***********.****************... .

37. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

38. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

39. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

40. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

41. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcgacgcatcaggcatcggc	Protospacer
 ****** ********** **********...*.

42. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcggcgcatcaggcatcggt	Protospacer
 ****** ********** **********...*.

43. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcggcgcatcaggcatcggt	Protospacer
 ****** ********** **********...*.

44. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcatctgc	Protospacer
 ***********.****************... .

45. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

46. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

47. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

48. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

49. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcgacgcatcaggcatcggc	Protospacer
 ****** ********** **********...*.

50. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcggcgcatcaggcatcggt	Protospacer
 ****** ********** **********...*.

51. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcggcgcatcaggcatcggt	Protospacer
 ****** ********** **********...*.

52. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcatctgc	Protospacer
 ***********.****************... .

53. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

54. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

55. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

56. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

57. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcgacgcatcaggcatcggc	Protospacer
 ****** ********** **********...*.

58. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcggcgcatcaggcatcggt	Protospacer
 ****** ********** **********...*.

59. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcggcgcatcaggcatcggt	Protospacer
 ****** ********** **********...*.

60. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcatctgc	Protospacer
 ***********.****************... .

61. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

62. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

63. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

64. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcgtcgcatcaggcatctgc	Protospacer
 ************.***************... .

65. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcgacgcatcaggcatcggc	Protospacer
 ****** ********** **********...*.

66. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcggcgcatcaggcatcggt	Protospacer
 ****** ********** **********...*.

67. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagtcgcgtcagcggcgcatcaggcatcggt	Protospacer
 ****** ********** **********...*.

68. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagatgcgccagcgtcgcatcaggtaattca	Protospacer
 *******.***.***************.. *  *

69. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP044147 (Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgtatcaggcatctgc	Protospacer
 ********************.*******... .

70. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP044147 (Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcatccgg	Protospacer
 ***********.****************... ..

71. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to CP044351 (Escherichia coli strain 194195 plasmid p194195_1, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgtcagcgtcgtatcaggcatctgc	Protospacer
 ********************.*******... .

72. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to CP044351 (Escherichia coli strain 194195 plasmid p194195_1, complete sequence) position: , mismatch: 8, identity: 0.771

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcaggcatccgg	Protospacer
 ***********.****************... ..

73. spacer 2.1|3639930|32|NZ_CP018245|CRISPRCasFinder matches to NC_015512 (Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY02, complete sequence) position: , mismatch: 8, identity: 0.75

agcggcacgctggattgaacaaat---ccctgggc	CRISPR spacer
tgcggcacgatgggttgaacaaatggactttg---	Protospacer
 ******** ***.**********   *..**

74. spacer 2.6|3640053|31|NZ_CP018245|CRT,PILER-CR matches to NC_011370 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG203, complete sequence) position: , mismatch: 8, identity: 0.742

ttggtgacagtttttgtcactgttttggtga	CRISPR spacer
cagtcaagagtctttggcactgttttggtga	Protospacer
. * ..* ***.**** **************

75. spacer 2.6|3640053|31|NZ_CP018245|CRT,PILER-CR matches to NZ_CP032697 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525a, complete sequence) position: , mismatch: 8, identity: 0.742

ttggtgacagtttttgtcactgttttggtga	CRISPR spacer
cagtcaagagtctttggcactgttttggtga	Protospacer
. * ..* ***.**** **************

76. spacer 2.6|3640053|31|NZ_CP018245|CRT,PILER-CR matches to NZ_CP049249 (Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

ttggtgacagtttttgtcactgttttggtga	CRISPR spacer
cagtcaagagtttttggcaccgttttggtga	Protospacer
. * ..* ******** ***.**********

77. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 9, identity: 0.743

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgttagcatcgcatcaggcatcagc	Protospacer
 ************.***.***********.....

78. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 9, identity: 0.743

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgctagcgtcgcatcaggcatctgc	Protospacer
 ***********..***************... .

79. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 9, identity: 0.743

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgctagcgtcgcatcaggcatctgc	Protospacer
 ***********..***************... .

80. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 9, identity: 0.743

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgctagcgtcgcatcaggcatctgc	Protospacer
 ***********..***************... .

81. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 9, identity: 0.743

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgctagcgtcgcatcaggcatctgc	Protospacer
 ***********..***************... .

82. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP044308 (Escherichia coli strain C27A plasmid pC27A-3, complete sequence) position: , mismatch: 9, identity: 0.743

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
cgataagacgcgccagcgtcgcatcgggcatccgt	Protospacer
 ***********.************.***... .

83. spacer 1.1|71540|35|NZ_CP018245|CRISPRCasFinder matches to NZ_CP019246 (Escherichia coli strain Combat13F7 plasmid pCombat13F7-1, complete sequence) position: , mismatch: 9, identity: 0.743

agataagacgcgtcagcgtcgcatcaggcgctgaa	CRISPR spacer
tgataagacgcgccagcgtcgcatcagacatcagc	Protospacer
 ***********.**************.*.....

84. spacer 2.3|3640052|32|NZ_CP018245|CRISPRCasFinder matches to NC_011370 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG203, complete sequence) position: , mismatch: 9, identity: 0.719

tttggtgacagtttttgtcactgttttggtga	CRISPR spacer
acagtcaagagtctttggcactgttttggtga	Protospacer
 . * ..* ***.**** **************

85. spacer 2.3|3640052|32|NZ_CP018245|CRISPRCasFinder matches to NZ_CP032697 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525a, complete sequence) position: , mismatch: 9, identity: 0.719

tttggtgacagtttttgtcactgttttggtga	CRISPR spacer
gcagtcaagagtctttggcactgttttggtga	Protospacer
 . * ..* ***.**** **************

86. spacer 2.3|3640052|32|NZ_CP018245|CRISPRCasFinder matches to NZ_CP049249 (Rhizobium rhizoryzae strain DSM 29514 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.719

tttggtgacagtttttgtcactgttttggtga	CRISPR spacer
gcagtcaagagtttttggcaccgttttggtga	Protospacer
 . * ..* ******** ***.**********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

215671 : 279926

uncultured_Caudovirales_phage(25.0%)

tRNA,plate,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000176537.1\|215671_216967_+\|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA
WP_000062312.1\|217019_217280_-	Rho-binding antiterminator	NA	NA	NA	NA
WP_000417058.1\|217266_217467_-	YaeP family protein	NA	NA	NA	NA
WP_001185286.1\|217632_218178_+	YaeQ family protein	NA	NA	NA	NA
WP_000635546.1\|218174_218585_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_000239181.1\|218598_219309_+	envelope stress response activation lipoprotein NlpE	NA	NA	NA	NA
WP_001302206.1\|219508_220333_-	YaeF family permuted papain-like enzyme	NA	NA	NA	NA
WP_001260720.1\|220385_222104_-\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_000094000.1\|222214_222922_-\|tRNA	tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO	NA	NA	NA	NA
WP_001202328.1\|222918_223323_-	Rcs stress response system protein RcsF	NA	NA	NA	NA
WP_000874227.1\|223440_224256_-	methionine ABC transporter substrate-binding lipoprotein MetQ	NA	NA	NA	NA
WP_001294606.1\|224295_224949_-	methionine ABC transporter permease MetI	NA	NA	NA	NA
WP_000593994.1\|224941_225973_-	methionine ABC transporter ATP-binding protein MetN	G9BWD6	Planktothrix_phage	7.2e-36	40.2
WP_001140187.1\|226160_226736_+	D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase	NA	NA	NA	NA
WP_000997018.1\|232493_233297_+	2,5-didehydrogluconate reductase DkgB	A0A1V0SDE7	Indivirus	5.4e-39	36.6
WP_000648586.1\|233293_234208_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_001230983.1\|234448_235249_+	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_000211693.1\|235326_236097_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000644686.1\|236144_237503_-	murein transglycosylase D	A0A2H4J9N7	uncultured_Caudovirales_phage	5.8e-09	36.0
WP_001052715.1\|237574_238330_-	hydroxyacylglutathione hydrolase	NA	NA	NA	NA
WP_001301721.1\|238363_239086_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000917883.1\|239082_239550_-	ribonuclease HI	J9Q745	Salmonella_phage	1.0e-50	58.7
WP_001301976.1\|239614_240346_+	DNA polymerase III subunit epsilon	A0A1X9SH08	Bradyrhizobium_phage	9.9e-40	39.5
WP_001086136.1\|240883_241684_+	hypothetical protein	NA	NA	NA	NA
WP_001302684.1\|242161_242611_-	DUF1311 domain-containing protein	NA	NA	NA	NA
WP_000964776.1\|242613_243210_-	hypothetical protein	NA	NA	NA	NA
WP_000002701.1\|243288_243510_-	hypothetical protein	NA	NA	NA	NA
WP_001284958.1\|243530_244010_-	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_001087743.1\|243975_245385_-	ImpA family type VI secretion system protein	NA	NA	NA	NA
WP_001303798.1\|245395_248830_-	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_001240517.1\|248966_250379_-	type VI secretion system protein TssA	NA	NA	NA	NA
WP_000088854.1\|250383_251127_-	type VI secretion system-associated protein TagO	NA	NA	NA	NA
WP_000614375.1\|251123_253901_-	type VI secretion system ATPase TssH	H6X3M6	Enterobacteria_phage	4.7e-82	28.7
WP_000343292.1\|253909_254671_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_000246434.1\|254675_256007_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_001080153.1\|256009_256534_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_001113707.1\|256530_257811_-	type VI secretion system-associated FHA domain protein TagH	NA	NA	NA	NA
WP_000348794.1\|257835_258918_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_000393844.1\|258881_260732_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_000599596.1\|260735_261149_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_000056994.1\|261239_262631_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_000123970.1\|262681_262906_-	hypothetical protein	NA	NA	NA	NA
WP_000037399.1\|262940_263441_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_001142958.1\|264137_264656_+	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_000103335.1\|264865_267007_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	1.4e-25	25.0
WP_149026308.1\|267082_271315_+	RHS domain-containing protein	A0A2H4JHK7	uncultured_Caudovirales_phage	2.1e-25	46.1
WP_000995683.1\|271454_272171_+	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_001452927.1\|273929_274463_+	sel1 repeat family protein	NA	NA	NA	NA
WP_000420853.1\|275208_276345_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_000247943.1\|278309_278573_+	hypothetical protein	NA	NA	NA	NA
WP_120795385.1\|278487_278673_-	protein YncO	NA	NA	NA	NA
WP_000027427.1\|278753_279926_+\|transposase	ISAs1-like element ISEc26 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

300054 : 312642

Escherichia_phage(40.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001285288.1\|300054_301158_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.1e-61	40.4
WP_000893282.1\|301169_302423_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	3.4e-96	47.2
WP_001303805.1\|303492_303738_-	transcription antitermination protein	J3JZZ6	Escherichia_phage	1.0e-12	90.5
WP_162829202.1\|304064_305278_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	7.6e-170	100.0
WP_001274756.1\|306383_307097_-	LexA family transcriptional regulator	A4KWV9	Enterobacteria_phage	3.5e-130	99.2
WP_000437875.1\|307197_307398_+	hypothetical protein	A4KWT7	Enterobacteria_phage	4.3e-30	100.0
WP_000251067.1\|307516_307810_+	lambda phage CII family protein	A2SY75	Escherichia_phage	1.4e-45	99.0
WP_000788819.1\|308761_309073_+	hypothetical protein	A0A0M5M1K4	Salmonella_phage	9.7e-29	73.2
WP_000904979.1\|311256_311811_+	site-specific DNA recombinase	A0A0F7LA37	Escherichia_phage	2.8e-87	88.4
WP_000355475.1\|311868_312642_-	hypothetical protein	A0A289ZIY5	Serratia_phage	5.0e-50	44.7

DBSCAN-SWA_3

896373 : 935786

Enterobacteria_phage(50.0%)

lysis,tail,portal,holin,transposase,terminase,integrase,protease

attL 885815:885829|attR 919422:919436

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
885815:885829	attL	NA	NA	NA	NA
WP_089625990.1\|896373_897312_-\|integrase	tyrosine-type recombinase/integrase	K7P6P6	Enterobacteria_phage	2.0e-173	99.7
WP_162829202.1\|897437_898650_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	7.6e-170	100.0
WP_001303849.1\|898734_898953_-	excisionase	Q77WA4	Escherichia_phage	3.7e-35	100.0
WP_000545728.1\|898992_899160_-	hypothetical protein	A0A0K2FJ46	Enterobacteria_phage	1.3e-27	98.2
WP_000120056.1\|899402_900005_+	hypothetical protein	NA	NA	NA	NA
WP_000763363.1\|900215_900437_-	TraR/DksA family transcriptional regulator	A0A0N7C211	Escherichia_phage	6.4e-35	98.6
WP_000188862.1\|900535_900751_-	hypothetical protein	A0A1I9LJM7	Stx_converting_phage	2.9e-32	98.6
WP_000548536.1\|900827_901019_-	DUF1382 family protein	A0A0P0ZC67	Stx2-converting_phage	1.1e-25	96.8
WP_000682316.1\|900991_901174_-	DUF1317 domain-containing protein	A0A0P0ZAS9	Stx2-converting_phage	4.1e-27	95.0
WP_000186844.1\|901170_901851_-	YqaJ viral recombinase family protein	A0A0P0ZCD4	Stx2-converting_phage	3.5e-132	99.6
WP_001254218.1\|902548_902731_+	NinE family protein	Q8H9Z6	Enterobacteria_phage	4.8e-28	96.7
WP_000567001.1\|902727_902898_+	protein ninF	Q716C4	Shigella_phage	7.9e-25	96.4
WP_001108055.1\|902890_903511_+	recombination protein NinG	Q716C3	Shigella_phage	1.6e-94	96.1
WP_001028854.1\|903507_904173_+	serine/threonine protein phosphatase	Q5TJL8	Enterobacteria_phage	5.0e-131	99.5
WP_000750155.1\|904384_905344_-	lipid A deacylase LpxR family protein	NA	NA	NA	NA
WP_032160865.1\|905681_905804_+	YlcG family protein	NA	NA	NA	NA
WP_001097238.1\|905818_906508_+	Q antiterminator encoded by prophage CP-933P	I6PDF8	Cronobacter_phage	1.5e-58	48.1
WP_001302581.1\|906691_907435_+	hypothetical protein	NA	NA	NA	NA
WP_000499454.1\|907520_907679_+	DUF3927 family protein	NA	NA	NA	NA
WP_012578864.1\|907759_908158_-	hypothetical protein	H6WZJ8	Escherichia_phage	6.9e-11	83.3
WP_000284524.1\|908300_908516_+\|holin	class II holin family protein	A0A0P0ZC45	Stx2-converting_phage	4.5e-33	98.6
WP_000075107.1\|908515_909013_+	lysozyme RrrD	A0A1B5FP97	Escherichia_phage	7.1e-90	98.2
WP_000092302.1\|909009_909477_+\|lysis	lysis protein	A0A291AWW3	Escherichia_phage	9.4e-76	97.4
WP_001139679.1\|909464_909617_+	hypothetical protein	K7PKL2	Enterobacteria_phage	8.9e-20	96.0
WP_000349509.1\|910291_910783_+	DUF1441 family protein	A0A291AWV8	Escherichia_phage	1.3e-72	87.2
WP_000934137.1\|910782_912885_+\|terminase	phage terminase large subunit family protein	A0A291AWY5	Escherichia_phage	0.0e+00	96.7
WP_001072975.1\|912881_913094_+	hypothetical protein	A5LH28	Enterobacteria_phage	1.1e-31	100.0
WP_010904538.1\|913021_914146_+\|portal	phage portal protein	K7PJP3	Enterobacteria_phage	5.4e-194	99.4
WP_127446149.1\|914267_914603_+\|portal	phage portal protein	A5LH29	Enterobacteria_phage	9.1e-57	99.1
WP_001136597.1\|914547_916575_+\|protease	Clp protease ClpP	K7PGT6	Enterobacteria_phage	0.0e+00	99.4
WP_001097050.1\|916661_916985_+	DUF2190 family protein	A0A291AWX2	Escherichia_phage	8.5e-52	100.0
WP_001283153.1\|916977_917253_+	DNA breaking-rejoining protein	K7PH43	Enterobacteria_phage	2.3e-45	100.0
WP_000677094.1\|917264_917843_+\|tail	phage tail protein	A5LH33	Enterobacteria_phage	6.1e-101	99.0
WP_001079422.1\|917839_918241_+\|tail	tail protein	A5LH34	Enterobacteria_phage	2.0e-71	98.5
WP_000211123.1\|918251_918995_+\|tail	phage tail protein	A5LH35	Enterobacteria_phage	9.5e-131	98.0
WP_001300035.1\|919055_919442_+\|tail	phage minor tail protein G	A0A291AWW5	Escherichia_phage	1.6e-65	100.0
919422:919436	attR	NA	NA	NA	NA
WP_001161009.1\|919450_919780_+\|tail	phage tail assembly protein T	A5LH37	Enterobacteria_phage	7.6e-56	100.0
WP_000371994.1\|919751_922817_+\|tail	phage tail tape measure protein	A0A291AWX1	Escherichia_phage	0.0e+00	98.9
WP_000447253.1\|922816_923146_+\|tail	phage tail protein	A5LH39	Enterobacteria_phage	1.7e-60	100.0
WP_001152360.1\|923155_923854_+\|tail	phage minor tail protein L	A5LH40	Enterobacteria_phage	3.9e-134	99.1
WP_000194779.1\|923859_924603_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	2.0e-149	97.6
WP_000090841.1\|924539_925148_+\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	2.4e-100	94.1
WP_072616970.1\|925208_928622_+	host specificity protein J	K7PKJ2	Enterobacteria_phage	0.0e+00	97.0
WP_001233141.1\|928692_929292_+	Ail/Lom family outer membrane beta-barrel protein	H6WZM8	Escherichia_phage	1.8e-103	92.5
WP_000741874.1\|929351_930668_+\|tail	phage tail protein	Q6H9S9	Enterobacteria_phage	2.0e-67	95.6
WP_001024022.1\|930669_930939_+\|tail	phage tail fiber C-terminal domain-containing protein	A0A1I9LJT0	Stx_converting_phage	4.9e-45	98.9
WP_000950813.1\|931115_932096_+	type III secretion system effector arginine glycosyltransferase NleB2	Q8HAB2	Salmonella_phage	2.9e-87	49.5
WP_115801843.1\|932129_933149_+\|protease	type III secretion system effector zinc metalloprotease NleC	NA	NA	NA	NA
WP_072127173.1\|933645_933807_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	3.9e-13	72.5
WP_000951026.1\|933975_934857_+	type III secretion system effector kinase NleH1-1	A5LH48	Enterobacteria_phage	8.6e-147	90.1
WP_001247925.1\|935087_935786_+\|protease	T3SS effector zinc metalloprotease NleD	NA	NA	NA	NA

DBSCAN-SWA_4

1162019 : 1231849

Escherichia_phage(25.58%)

tail,head,portal,holin,transposase,capsid,integrase,protease

attL 1170507:1170522|attR 1191873:1191888

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000156526.1\|1162019_1163780_-\|protease	Lon protease family protein	NA	NA	NA	NA
WP_000877161.1\|1163965_1164418_+	macrodomain Ter protein MatP	NA	NA	NA	NA
WP_000750416.1\|1164493_1165534_-	porin OmpA	NA	NA	NA	NA
WP_000288710.1\|1165890_1166400_-	cell division inhibitor SulA	NA	NA	NA	NA
WP_000839159.1\|1166618_1167248_+	CRP-S regulon transcriptional coactivator Sxy	NA	NA	NA	NA
WP_000875023.1\|1167210_1169373_-	TIGR01666 family membrane protein	NA	NA	NA	NA
WP_001261230.1\|1169382_1169829_-	YccF domain-containing protein	NA	NA	NA	NA
WP_001301436.1\|1169951_1172006_+	DNA helicase IV	A7KV33	Bacillus_phage	5.9e-21	27.9
1170507:1170522	attL	NA	NA	NA	NA
WP_000424181.1\|1172037_1172496_-	methylglyoxal synthase	NA	NA	NA	NA
WP_000847791.1\|1172591_1173254_-	DUF2057 family protein	NA	NA	NA	NA
WP_000665217.1\|1173426_1173840_+	CoA-binding protein	NA	NA	NA	NA
WP_001295356.1\|1173884_1174202_-	heat shock protein HspQ	NA	NA	NA	NA
WP_000116288.1\|1174259_1175450_-	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	NA	NA	NA	NA
WP_000048252.1\|1175544_1175823_+	acylphosphatase	NA	NA	NA	NA
WP_000904442.1\|1175819_1176149_-	sulfurtransferase TusE	NA	NA	NA	NA
WP_000375128.1\|1176239_1176899_-\|protease	FtsH protease modulator YccA	A0A2H4JFM9	uncultured_Caudovirales_phage	1.8e-48	55.3
WP_001299351.1\|1177306_1178326_-\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	1.3e-85	49.7
WP_000273151.1\|1178303_1178546_-	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_000034474.1\|1178613_1181085_-	exonuclease	A0A192Y6E0	Salmonella_phage	8.8e-56	56.6
WP_001098307.1\|1181178_1181370_-	DUF1482 family protein	NA	NA	NA	NA
WP_000413705.1\|1181366_1181555_-	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001133046.1\|1182128_1182314_+	hypothetical protein	NA	NA	NA	NA
WP_000394511.1\|1182500_1182890_-	hypothetical protein	NA	NA	NA	NA
WP_000379575.1\|1183031_1183187_-	DUF1391 family protein	M4QQ57	Salicola_phage	3.0e-07	53.2
WP_001303876.1\|1183464_1183752_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_000536233.1\|1183751_1183943_-	hypothetical protein	NA	NA	NA	NA
WP_000986592.1\|1183970_1184372_-	helix-turn-helix domain-containing protein	A0A1B5FPF4	Escherichia_phage	7.4e-13	54.5
WP_000887453.1\|1184480_1184753_+	helix-turn-helix domain-containing protein	A0A0U2S629	Escherichia_phage	1.1e-12	45.8
WP_000693855.1\|1184736_1185162_+	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000273724.1\|1185368_1185824_-	hypothetical protein	NA	NA	NA	NA
WP_001205823.1\|1185902_1186994_+	hypothetical protein	V5URT9	Shigella_phage	5.1e-133	70.0
WP_000788751.1\|1187000_1187747_+	ATP-binding protein	A0A088CBP4	Shigella_phage	6.2e-114	84.2
WP_000450992.1\|1187768_1188539_+	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	6.1e-80	64.5
WP_001151233.1\|1188554_1188968_+	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	9.8e-61	89.1
WP_000160654.1\|1189319_1190093_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_000813263.1\|1190697_1190853_+	type I toxin-antitoxin system toxin HokD	A0A0U2QV81	Escherichia_phage	1.9e-17	94.1
WP_001341388.1\|1191020_1191299_+	hypothetical protein	I6PCV7	Cronobacter_phage	5.7e-12	48.4
WP_001265172.1\|1191300_1192350_+	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.2e-110	54.9
1191873:1191888	attR	NA	NA	NA	NA
WP_001217436.1\|1192362_1192734_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.3e-35	63.7
WP_000090264.1\|1192723_1193095_+	antitermination protein	Q777W5	Enterobacteria_phage	4.0e-53	83.2
WP_000265265.1\|1193246_1194065_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000261909.1\|1194685_1195399_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000874392.1\|1196166_1198017_+	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	96.1
WP_162829202.1\|1198192_1199405_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	7.6e-170	100.0
WP_001303878.1\|1199610_1199925_-	PerC family transcriptional regulator	NA	NA	NA	NA
WP_012816791.1\|1200452_1200638_-	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.2e-18	100.0
WP_000675931.1\|1200859_1200973_-	hypothetical protein	A0A2L1IV24	Escherichia_phage	6.6e-12	100.0
WP_001003118.1\|1201193_1201727_-	lysozyme	A0A1U9AJ98	Stx1_converting_phage	3.1e-99	94.4
WP_000138558.1\|1201886_1202159_+	hypothetical protein	NA	NA	NA	NA
WP_000411791.1\|1202414_1202621_-\|holin	class II holin family protein	Q6H9V8	Enterobacteria_phage	4.5e-30	97.1
WP_000235421.1\|1203371_1203647_+	hypothetical protein	A0A1I9KFT4	Aeromonas_phage	2.4e-10	51.5
WP_001171540.1\|1203722_1204103_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	7.1e-66	99.2
WP_000612591.1\|1204099_1204447_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_000998048.1\|1204496_1206035_+\|transposase	IS66-like element ISEc8 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.5e-300	100.0
WP_000259002.1\|1208196_1208403_+\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	7.9e-11	56.9
WP_000831796.1\|1208399_1209992_+\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	8.7e-182	60.5
WP_001254002.1\|1209981_1211487_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	1.2e-100	54.2
WP_000256723.1\|1211523_1211871_+\|head	head decoration protein	C6ZCY1	Enterobacteria_phage	2.6e-22	58.1
WP_001301534.1\|1211928_1212195_+\|capsid	major capsid protein	NA	NA	NA	NA
WP_029208397.1\|1212176_1212917_+\|tail	phage tail protein	Q687F6	Enterobacteria_phage	3.6e-130	98.0
WP_000479117.1\|1212930_1213362_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	2.4e-41	68.1
WP_000533402.1\|1213388_1213802_+\|tail	phage tail assembly protein T	S5MDP5	Escherichia_phage	1.6e-42	82.2
WP_001455418.1\|1213782_1215645_+\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	7.4e-265	82.5
WP_134790849.1\|1215596_1216361_+\|tail	phage tail tape measure protein	Q9EYE1	Enterobacteria_phage	8.6e-127	92.1
WP_000847304.1\|1216357_1216687_+\|tail	phage tail protein	Q687F2	Enterobacteria_phage	2.2e-55	95.4
WP_001151078.1\|1216686_1217385_+\|tail	phage minor tail protein L	H6WZM3	Escherichia_phage	2.9e-129	98.3
WP_000194760.1\|1217395_1218139_+\|tail	phage tail protein	A0A0P0ZE89	Stx2-converting_phage	2.4e-150	99.6
WP_000649829.1\|1218906_1219434_-	superoxide dismutase family protein	Q9MC02	Salmonella_phage	1.8e-59	60.5
WP_000515110.1\|1219567_1223041_+	host specificity protein J	A0A0P0ZCI5	Stx2-converting_phage	0.0e+00	96.4
WP_001230444.1\|1223108_1223708_+	Ail/Lom family outer membrane beta-barrel protein	A0A0P0ZCF6	Stx2-converting_phage	8.8e-111	99.0
WP_000268962.1\|1223772_1225086_+\|tail	phage tail protein	A0A0P0ZE15	Stx2-converting_phage	2.8e-77	97.0
WP_001023352.1\|1225087_1225357_+\|tail	phage tail fiber C-terminal domain-containing protein	A0A0P0ZEF0	Stx2-converting_phage	3.4e-46	100.0
WP_001301613.1\|1227630_1228749_+	hydrogenase 1 small subunit	NA	NA	NA	NA
WP_000107391.1\|1228745_1230539_+	Ni/Fe-hydrogenase large subunit	NA	NA	NA	NA
WP_001186424.1\|1230557_1231265_+	Ni/Fe-hydrogenase b-type cytochrome subunit	NA	NA	NA	NA
WP_000003653.1\|1231261_1231849_+\|protease	hydrogenase 1 maturation protease	NA	NA	NA	NA

DBSCAN-SWA_5

1494906 : 1566384

Stx2-converting_phage(30.65%)

tail,head,holin,transposase,capsid,terminase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_077699040.1\|1494906_1495296_-	3'-5' exoribonuclease	K7PLW7	Enterobacteria_phage	1.3e-38	60.0
WP_000559928.1\|1495428_1495944_+	hypothetical protein	NA	NA	NA	NA
WP_001414141.1\|1496058_1496211_-	DUF1391 family protein	M4QQ57	Salicola_phage	1.0e-07	55.3
WP_000948454.1\|1496526_1497003_-	hypothetical protein	A0A2D1GNH0	Pseudomonas_phage	5.7e-12	53.4
WP_000711018.1\|1497127_1497451_+	transcriptional regulator	A0A0R6PH31	Moraxella_phage	6.2e-10	44.9
WP_000693915.1\|1497434_1497860_+	Rha family transcriptional regulator	NA	NA	NA	NA
WP_001457513.1\|1497928_1498966_+	primosomal protein I	A0A0U2RT81	Escherichia_phage	1.5e-89	79.5
WP_072143019.1\|1498877_1499420_+	replication protein	A0A0U2JGJ0	Escherichia_phage	2.3e-81	92.2
WP_000451012.1\|1499453_1500170_+	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	2.1e-71	62.4
WP_072140318.1\|1500202_1500484_+	DNA-binding protein	A0A222YXX1	Escherichia_phage	1.4e-29	73.1
WP_001310212.1\|1500480_1500783_+	DUF4406 domain-containing protein	A0A0U2SAZ1	Escherichia_phage	1.9e-45	87.9
WP_001017965.1\|1500772_1501090_+	DUF4752 family protein	A0A1I9LJV1	Stx_converting_phage	2.1e-42	92.4
WP_000156547.1\|1501043_1501361_+	hypothetical protein	A0A088CQ13	Enterobacteria_phage	4.4e-45	90.0
WP_000515959.1\|1501347_1501785_+	ead/Ea22-like family protein	Q8VNQ2	Enterobacteria_phage	1.9e-38	94.0
WP_001014296.1\|1501786_1501978_+	hypothetical protein	G9L660	Escherichia_phage	1.6e-26	98.4
WP_000207955.1\|1501980_1502568_+	DUF551 domain-containing protein	K7PH57	Enterobacteria_phage	7.5e-38	45.8
WP_001278450.1\|1502683_1502788_+	hypothetical protein	NA	NA	NA	NA
WP_000887477.1\|1502976_1503189_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	3.1e-18	68.6
WP_001341388.1\|1503356_1503635_+	hypothetical protein	I6PCV7	Cronobacter_phage	5.7e-12	48.4
WP_001265168.1\|1503636_1504686_+	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.2e-107	53.4
WP_001217410.1\|1504698_1505073_+	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	2.1e-33	62.7
WP_000762929.1\|1505069_1505891_+	antitermination protein	K7P7B9	Enterobacteria_phage	1.3e-83	58.6
WP_000023170.1\|1506969_1508907_+	SASA family carbohydrate esterase	Q6H9W1	Enterobacteria_phage	2.5e-292	76.8
WP_001213059.1\|1509054_1509237_+	DUF1378 family protein	A0A2R2Z345	Escherichia_phage	1.0e-14	67.8
WP_001289717.1\|1509274_1509544_+	DUF826 domain-containing protein	A0A2R2Z348	Escherichia_phage	8.2e-08	75.3
WP_000284518.1\|1509619_1509835_+\|holin	class II holin family protein	Q6H9V8	Enterobacteria_phage	2.0e-33	100.0
WP_000731241.1\|1509839_1510184_+	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	1.7e-58	99.1
WP_000992148.1\|1510234_1510768_+	lysozyme	B6DZ92	Enterobacteria_phage	3.0e-102	99.4
WP_001056806.1\|1511038_1511608_+	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	3.1e-105	100.0
WP_000539792.1\|1511607_1511754_+	hypothetical protein	A0A0P0ZE99	Stx2-converting_phage	2.6e-16	100.0
WP_001208682.1\|1511981_1512188_+	hypothetical protein	H6WRZ6	Salmonella_phage	7.1e-12	64.7
WP_000735655.1\|1512252_1512477_+	hypothetical protein	NA	NA	NA	NA
WP_000347013.1\|1512833_1512974_+	hypothetical protein	NA	NA	NA	NA
WP_001302977.1\|1513103_1513289_-	DUF3950 domain-containing protein	H6WZK6	Escherichia_phage	3.7e-20	90.4
WP_000279786.1\|1513330_1513696_+	HNH endonuclease	B6DZ96	Enterobacteria_phage	9.9e-65	99.2
WP_000958387.1\|1513984_1514548_+\|terminase	terminase small subunit	A0A0N7KZJ8	Stx2-converting_phage	8.1e-90	100.0
WP_038425863.1\|1514544_1516206_+\|terminase	terminase large subunit	A0A0P0ZD10	Stx2-converting_phage	0.0e+00	99.8
WP_000173030.1\|1516269_1518207_+\|capsid	phage major capsid protein	B6ETE8	Enterobacteria_phage	0.0e+00	100.0
WP_001063099.1\|1518251_1518473_+	hypothetical protein	B6DZA0	Enterobacteria_phage	5.8e-36	100.0
WP_000126019.1\|1520999_1521326_+\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDA0	Stx2-converting_phage	9.2e-54	100.0
WP_001007901.1\|1521335_1521686_+\|head	phage head closure protein	A0A0P0ZCU6	Stx2-converting_phage	7.0e-60	100.0
WP_000573374.1\|1521682_1522129_+	HK97 gp10 family phage protein	A0A0P0ZCD2	Stx2-converting_phage	8.1e-77	100.0
WP_000133388.1\|1522125_1522470_+	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
WP_001275508.1\|1522528_1523245_+\|tail	tail protein	A0A0P0ZD29	Stx2-converting_phage	2.9e-129	100.0
WP_001030063.1\|1523250_1523625_+\|tail	phage tail assembly chaperone	A0A0N7KZA2	Stx2-converting_phage	7.8e-65	100.0
WP_001453698.1\|1523720_1523930_+	DUF4035 domain-containing protein	A0A0P0ZDE6	Stx2-converting_phage	2.0e-33	100.0
WP_072616981.1\|1523982_1527225_+\|tail	phage tail tape measure protein	A0A0P0ZDY0	Stx2-converting_phage	0.0e+00	98.6
WP_000807954.1\|1527217_1527559_+\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	5.1e-63	100.0
WP_072616982.1\|1527558_1528257_+\|tail	phage minor tail protein L	Q6H9T5	Enterobacteria_phage	6.8e-131	98.3
WP_000194720.1\|1528267_1529011_+\|tail	phage tail protein	A0A0P0ZE89	Stx2-converting_phage	5.0e-148	97.6
WP_050439450.1\|1528956_1529589_+\|tail	tail assembly protein	B6ETG3	Enterobacteria_phage	3.9e-101	97.1
WP_072616983.1\|1529931_1533405_+	host specificity protein J	A0A0P0ZBW1	Stx2-converting_phage	0.0e+00	90.4
WP_001228304.1\|1533472_1534072_+	Ail/Lom family outer membrane beta-barrel protein	Q9EV15	Enterobacteria_phage	1.6e-107	96.5
WP_000216532.1\|1534223_1535537_+\|tail	phage tail protein	A0A0P0ZE15	Stx2-converting_phage	2.1e-80	97.9
WP_001023474.1\|1535538_1535808_+\|tail	phage tail fiber C-terminal domain-containing protein	A0A1U9AJC2	Stx1_converting_phage	3.2e-44	98.9
WP_001025672.1\|1536834_1538160_-	type III secretion system effector NleA	H6WZN2	Escherichia_phage	1.9e-214	81.2
WP_106409364.1\|1539759_1539882_+\|tail	phage tail fiber C-terminal domain-containing protein	Q687E5	Enterobacteria_phage	3.8e-05	91.3
WP_000950979.1\|1539988_1540900_+	type III secretion system effector kinase NleH1-2	A5LH48	Enterobacteria_phage	3.0e-134	82.2
WP_000938103.1\|1540965_1541535_+	T3SS effector caspase inhibitor NleF	NA	NA	NA	NA
WP_000998048.1\|1542500_1544039_-\|transposase	IS66-like element ISEc8 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.5e-300	100.0
WP_000612591.1\|1544088_1544436_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_001171540.1\|1544432_1544813_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	7.1e-66	99.2
WP_001303943.1\|1545152_1545431_-	hypothetical protein	NA	NA	NA	NA
WP_001414184.1\|1545858_1546005_+	hypothetical protein	NA	NA	NA	NA
WP_001303944.1\|1546141_1546789_-	T3SS effector E3 ubiquitin-protein ligase NleG	B6ETE1	Enterobacteria_phage	1.6e-41	41.1
WP_001144877.1\|1546972_1547563_+	T3SS effector guanine nucleotide exchange factor EspM1	NA	NA	NA	NA
WP_001345079.1\|1549069_1549720_+	DUF1076 domain-containing protein	B6ETE1	Enterobacteria_phage	6.6e-27	32.4
WP_001079499.1\|1551033_1551540_-	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_001056499.1\|1551585_1552086_-	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_000807651.1\|1552171_1552351_-	general stress protein	NA	NA	NA	NA
WP_000443092.1\|1552731_1553538_-	tryptophan synthase subunit alpha	NA	NA	NA	NA
WP_000209521.1\|1553537_1554731_-	tryptophan synthase subunit beta	NA	NA	NA	NA
WP_000983857.1\|1554742_1556104_-	bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF	A0A0P0IR83	Acinetobacter_phage	4.3e-36	40.2
WP_000763520.1\|1556104_1557700_-	bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD	A0A0N7IRD9	Acinetobacter_phage	5.0e-52	38.2
WP_001194607.1\|1557699_1559262_-	anthranilate synthase component I	NA	NA	NA	NA
WP_001700591.1\|1559353_1559398_-	trp operon leader peptide	NA	NA	NA	NA
WP_001285675.1\|1559535_1560417_+	5'-3' exoribonuclease	NA	NA	NA	NA
WP_001295575.1\|1560413_1561034_+	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
WP_001302160.1\|1561061_1562645_+	DUF2207 domain-containing protein	NA	NA	NA	NA
WP_001291216.1\|1562857_1563730_+	23S rRNA pseudouridine(2605) synthase RluB	NA	NA	NA	NA
WP_001278878.1\|1563769_1564360_-	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
WP_000559268.1\|1564356_1565115_-	YciK family oxidoreductase	A0A0N9R355	Chrysochromulina_ericina_virus	6.7e-07	23.9
WP_000422055.1\|1565334_1566384_+\|protease	protease SohB	A0A2H4UUF9	Bodo_saltans_virus	1.3e-21	31.5

DBSCAN-SWA_6

1650025 : 1703812

Stx2-converting_phage(43.86%)

tail,head,holin,tRNA,capsid,terminase,integrase

attL 1655362:1655387|attR 1705807:1705832

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000628061.1\|1650025_1651258_-	diguanylate cyclase DgcM	A0A127AWB9	Bacillus_phage	3.1e-17	39.5
WP_000387388.1\|1651512_1652496_+	zinc transporter ZntB	NA	NA	NA	NA
WP_001625136.1\|1652770_1652941_+	hypothetical protein	NA	NA	NA	NA
WP_000123746.1\|1652973_1654347_+	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	6.6e-53	33.1
WP_001157382.1\|1654475_1655411_-\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	5.4e-147	99.6
1655362:1655387	attL	NA	NA	NA	NA
WP_001358842.1\|1655462_1656698_-\|integrase	site-specific integrase	A0A0U2JGI6	Escherichia_phage	2.3e-238	98.5
WP_000079602.1\|1656699_1656915_-	excisionase XisR	A0A0U2RY08	Escherichia_phage	2.3e-37	98.6
WP_001302840.1\|1657014_1657203_-	DUF1187 family protein	A0A0U2QL97	Escherichia_phage	5.5e-27	98.4
WP_001502425.1\|1657446_1658256_-	recombination protein RecT	A0A1P8DTF2	Proteus_phage	6.8e-106	71.5
WP_001502426.1\|1658248_1660849_-	exodeoxyribonuclease VIII	A0A0U2I1R6	Escherichia_phage	5.1e-248	63.2
WP_001502427.1\|1660950_1661226_-	bacteriophage protein	A0A0U2QW85	Escherichia_phage	5.2e-42	95.6
WP_065336296.1\|1661299_1661470_-	hypothetical protein	A0A0U2SHB5	Escherichia_phage	1.0e-16	71.4
WP_000560228.1\|1661469_1661691_-	killing protein KilR	A0A0U2RTC4	Escherichia_phage	2.4e-37	98.6
WP_000935592.1\|1661737_1662586_-	Rha family phage regulatory protein	A0A0P0ZE80	Stx2-converting_phage	5.9e-60	60.8
WP_001169149.1\|1663014_1663167_-	DUF1391 family protein	M4QQ57	Salicola_phage	2.1e-08	57.4
WP_001253182.1\|1663547_1664012_-	helix-turn-helix domain-containing protein	A0A0U2QW76	Escherichia_phage	1.2e-54	69.5
WP_000171139.1\|1664116_1664392_+	helix-turn-helix domain-containing protein	A0A0U2S629	Escherichia_phage	1.4e-23	65.9
WP_000702023.1\|1664375_1664798_+	hypothetical protein	A0A0U2RXZ9	Escherichia_phage	5.3e-70	95.0
WP_000899743.1\|1664810_1665668_+	DUF1376 domain-containing protein	A0A0U2RT81	Escherichia_phage	4.0e-80	94.4
WP_000788990.1\|1665674_1666421_+	ATP-binding protein	V5UQI5	Shigella_phage	2.8e-114	80.9
WP_072616986.1\|1666442_1667195_+	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	1.8e-76	63.6
WP_001502613.1\|1667181_1667910_+	ead/Ea22-like family protein	A0A0U2QW67	Escherichia_phage	4.3e-51	54.8
WP_000172332.1\|1667906_1668392_+	class I SAM-dependent methyltransferase	H9C170	Pectobacterium_phage	5.7e-68	77.1
WP_072616987.1\|1669787_1670450_+	DUF551 domain-containing protein	A0A1U9AJ59	Stx1_converting_phage	9.5e-74	54.5
WP_001278450.1\|1670565_1670670_+	hypothetical protein	NA	NA	NA	NA
WP_024175526.1\|1670858_1671071_+	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	4.0e-26	91.4
WP_000119356.1\|1671281_1671461_+	hypothetical protein	NA	NA	NA	NA
WP_000818161.1\|1671479_1671965_+	type II toxin-antitoxin system death-on-curing family toxin	NA	NA	NA	NA
WP_000687443.1\|1672165_1672339_+	hypothetical protein	A0A0U2I1S4	Escherichia_phage	7.3e-18	72.2
WP_001502554.1\|1672398_1672998_+	DUF1367 family protein	A0A0U2RT94	Escherichia_phage	7.7e-107	92.5
WP_000228020.1\|1672997_1673288_+	DUF1364 domain-containing protein	A0A0U2KD41	Escherichia_phage	3.3e-47	89.6
WP_001502553.1\|1673284_1673827_+	DUF1133 family protein	A0A0U2S606	Escherichia_phage	1.1e-75	74.0
WP_000735807.1\|1674312_1674537_+	hypothetical protein	NA	NA	NA	NA
WP_024175525.1\|1674589_1674811_+	hypothetical protein	NA	NA	NA	NA
WP_001359877.1\|1674989_1675421_+	tellurite resistance protein	H6WZJ6	Escherichia_phage	3.6e-66	96.5
WP_072616988.1\|1675991_1677842_+	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	98.7
WP_029785460.1\|1678276_1678492_+\|holin	class II holin family protein	Q6H9V8	Enterobacteria_phage	1.7e-32	97.2
WP_000731236.1\|1678496_1678841_+	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	1.0e-58	100.0
WP_000992168.1\|1678891_1679425_+	lysozyme	A0A0N7KZF9	Stx2-converting_phage	4.3e-101	99.4
WP_001056806.1\|1679695_1680265_+	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	3.1e-105	100.0
WP_000539792.1\|1680264_1680411_+	hypothetical protein	A0A0P0ZE99	Stx2-converting_phage	2.6e-16	100.0
WP_012816791.1\|1680638_1680824_+	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.2e-18	100.0
WP_000095749.1\|1681248_1681476_-	DUF3950 domain-containing protein	A0A0P0ZCA1	Stx2-converting_phage	3.9e-35	100.0
WP_001303046.1\|1681517_1681883_+	HNH endonuclease	A0A0P0ZCH0	Stx2-converting_phage	2.0e-65	100.0
WP_000958380.1\|1682170_1682734_+\|terminase	terminase small subunit	A0A0P0ZD56	Stx2-converting_phage	1.1e-89	100.0
WP_001399867.1\|1682730_1684392_+\|terminase	terminase large subunit	A0A0N7KZG0	Stx2-converting_phage	0.0e+00	99.6
WP_000173079.1\|1684455_1686393_+\|capsid	phage major capsid protein	A0A0P0ZCT9	Stx2-converting_phage	0.0e+00	100.0
WP_001063025.1\|1686437_1686659_+	hypothetical protein	A0A0P0ZD92	Stx2-converting_phage	5.8e-36	100.0
WP_000126019.1\|1689184_1689511_+\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDA0	Stx2-converting_phage	9.2e-54	100.0
WP_001007901.1\|1689520_1689871_+\|head	phage head closure protein	A0A0P0ZCU6	Stx2-converting_phage	7.0e-60	100.0
WP_000573374.1\|1689867_1690314_+	HK97 gp10 family phage protein	A0A0P0ZCD2	Stx2-converting_phage	8.1e-77	100.0
WP_000133388.1\|1690310_1690655_+	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
WP_001275508.1\|1690713_1691430_+\|tail	tail protein	A0A0P0ZD29	Stx2-converting_phage	2.9e-129	100.0
WP_001030063.1\|1691435_1691810_+\|tail	phage tail assembly chaperone	A0A0N7KZA2	Stx2-converting_phage	7.8e-65	100.0
WP_001453698.1\|1691905_1692115_+	DUF4035 domain-containing protein	A0A0P0ZDE6	Stx2-converting_phage	2.0e-33	100.0
WP_000212915.1\|1692167_1695410_+\|tail	phage tail tape measure protein	A0A0P0ZDY0	Stx2-converting_phage	0.0e+00	99.4
WP_000807954.1\|1695402_1695744_+\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	5.1e-63	100.0
WP_059214312.1\|1695743_1696442_+\|tail	phage minor tail protein L	A0A0P0ZBE3	Stx2-converting_phage	4.0e-131	97.8
WP_072616989.1\|1696452_1697196_+\|tail	phage tail protein	Q9EYE4	Enterobacteria_phage	3.0e-145	95.1
WP_140439088.1\|1697141_1697774_+\|tail	tail assembly protein	A0A0P0ZDX8	Stx2-converting_phage	7.9e-102	95.2
WP_072616991.1\|1698022_1701496_+	host specificity protein J	A0A0P0ZCI5	Stx2-converting_phage	0.0e+00	96.6
WP_001230471.1\|1701563_1702163_+	Ail/Lom family outer membrane beta-barrel protein	A0A0P0ZCF6	Stx2-converting_phage	9.7e-110	98.0
WP_072617073.1\|1702227_1703541_+\|tail	phage tail protein	A0A0P0ZD68	Stx2-converting_phage	4.1e-76	98.6
WP_001023356.1\|1703542_1703812_+\|tail	phage tail fiber C-terminal domain-containing protein	A0A2R2Z347	Escherichia_phage	2.4e-44	98.9
1705807:1705832	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1888200 : 1986466

121

Escherichia_phage(30.77%)

tail,lysis,head,portal,holin,transposase,capsid,terminase,integrase

attL 1931478:1931491|attR 1987345:1987358

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000214712.1\|1888200_1888404_+	putative selenium delivery protein YdfZ	J9Q802	Salmonella_phage	1.6e-11	55.2
WP_000527769.1\|1888439_1889900_-	mannitol dehydrogenase family protein	H8ZJP8	Ostreococcus_tauri_virus	1.9e-42	29.6
WP_001120551.1\|1891403_1891646_+	DinI-like family protein	Q687E4	Enterobacteria_phage	2.4e-27	83.3
WP_001143804.1\|1891807_1892449_-	DUF1076 domain-containing protein	B6DZC0	Enterobacteria_phage	3.8e-104	96.7
WP_001356599.1\|1892530_1893160_-	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	6.1e-78	91.5
WP_001131658.1\|1893232_1893808_-	DUF1076 domain-containing protein	H6WZN1	Escherichia_phage	4.1e-89	88.9
WP_001023407.1\|1893921_1894191_-\|tail	phage tail fiber C-terminal domain-containing protein	H6WZN0	Escherichia_phage	1.4e-44	98.9
WP_072616998.1\|1894192_1895506_-\|tail	phage tail protein	A0A0P0ZE15	Stx2-converting_phage	1.3e-77	97.3
WP_001230508.1\|1895570_1896170_-	Ail/Lom family outer membrane beta-barrel protein	A0A0P0ZE39	Stx2-converting_phage	1.2e-110	100.0
WP_072616999.1\|1896237_1899717_-	host specificity protein J	B6DZB5	Enterobacteria_phage	0.0e+00	98.3
WP_064562156.1\|1899957_1900587_-\|tail	tail assembly protein	A0A0P0ZEN7	Stx2-converting_phage	1.2e-105	99.5
WP_054191786.1\|1900532_1901276_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	2.1e-146	96.8
WP_072617001.1\|1901286_1901985_-\|tail	phage minor tail protein L	A0A0N7KZH0	Stx2-converting_phage	1.2e-130	98.7
WP_000847298.1\|1901984_1902314_-\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
WP_072617002.1\|1902310_1904923_-\|tail	phage tail tape measure protein	Q687F3	Enterobacteria_phage	0.0e+00	95.2
WP_000533440.1\|1904903_1905317_-\|tail	phage tail assembly protein T	Q687F4	Enterobacteria_phage	3.2e-43	83.2
WP_000479046.1\|1905343_1905766_-\|tail	phage minor tail protein G	Q687F5	Enterobacteria_phage	2.4e-70	97.9
WP_000235090.1\|1905779_1906532_-\|tail	phage tail protein	Q687F6	Enterobacteria_phage	5.8e-136	100.0
WP_000683063.1\|1906539_1906935_-\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	3.3e-58	81.7
WP_000975020.1\|1906931_1907465_-\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	5.9e-58	66.7
WP_000753016.1\|1907479_1907833_-\|head,tail	head-tail joining protein	A0A2R9YJJ5	Escherichia_phage	1.9e-57	92.3
WP_000158906.1\|1907844_1908243_-	DNA-packaging protein FI	A0A0K2FIR1	Enterobacteria_phage	3.5e-63	98.5
WP_000063265.1\|1908284_1909310_-\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	8.7e-191	98.8
WP_001457523.1\|1909365_1909698_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	1.9e-54	98.2
WP_000123254.1\|1909707_1911027_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	3.4e-232	98.2
WP_001301524.1\|1911007_1912609_-\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	1.4e-307	98.7
WP_000198153.1\|1912605_1912812_-	gpW family protein	A0A2R9YJL2	Escherichia_phage	2.2e-29	98.5
WP_001027230.1\|1912808_1914734_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	98.1
WP_000867498.1\|1914708_1915254_-\|terminase	terminase small subunit	A0A0K2FIG2	Enterobacteria_phage	9.6e-80	83.3
WP_001303940.1\|1915640_1915865_+	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	1.7e-19	90.6
WP_001302717.1\|1915946_1916261_-	PerC family transcriptional regulator	NA	NA	NA	NA
WP_072617003.1\|1916724_1917192_-\|lysis	lysis protein	Q9EYC9	Enterobacteria_phage	3.2e-68	88.3
WP_000539792.1\|1917199_1917346_-	hypothetical protein	A0A0P0ZE99	Stx2-converting_phage	2.6e-16	100.0
WP_001056806.1\|1917345_1917915_-	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	3.1e-105	100.0
WP_000992148.1\|1918185_1918719_-	lysozyme	B6DZ92	Enterobacteria_phage	3.0e-102	99.4
WP_000731241.1\|1918769_1919114_-	YdfR family protein	A0A0P0ZD64	Stx2-converting_phage	1.7e-58	99.1
WP_187655776.1\|1919118_1919334_-\|holin	class II holin family protein	A0A0P0ZC45	Stx2-converting_phage	5.0e-32	95.8
WP_072617005.1\|1919772_1921623_-	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	98.7
WP_001302123.1\|1922100_1922532_-	tellurite resistance protein	H6WZJ6	Escherichia_phage	1.6e-66	96.5
WP_000301797.1\|1922982_1923696_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000917763.1\|1923831_1924029_-	hypothetical protein	S5MQK8	Escherichia_phage	8.9e-28	96.9
WP_000640035.1\|1924253_1924808_-	DUF1133 family protein	A0A0U2S606	Escherichia_phage	1.0e-65	67.4
WP_001217444.1\|1924870_1925176_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	7.1e-32	66.3
WP_001265229.1\|1925188_1926238_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.2e-110	54.6
WP_000191872.1\|1926239_1926512_-	hypothetical protein	S4TNP0	Salmonella_phage	1.1e-12	53.0
WP_000756596.1\|1926633_1926978_-	YgiW/YdeI family stress tolerance OB fold protein	A0A1I9LJU6	Stx_converting_phage	6.1e-56	99.1
WP_000935259.1\|1927097_1927310_-	type I toxin-antitoxin system Hok family toxin	A0A0P0ZAX5	Stx2-converting_phage	6.0e-30	100.0
WP_000104474.1\|1927543_1928101_-	DUF551 domain-containing protein	A0A0N7KZV3	Escherichia_phage	2.8e-34	41.7
WP_000683609.1\|1928102_1928321_-	DUF4014 family protein	A0A2R2Z311	Escherichia_phage	2.3e-21	72.2
WP_001289673.1\|1928448_1928760_-	hypothetical protein	A0A0U2QV73	Escherichia_phage	7.2e-56	92.2
WP_000699809.1\|1928752_1928980_-	hypothetical protein	A0A1B5FPG2	Escherichia_phage	5.1e-11	49.3
WP_000603384.1\|1928976_1929258_-	DNA-binding protein	A0A222YXX1	Escherichia_phage	1.0e-29	73.6
WP_000450627.1\|1929290_1930007_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	3.3e-72	62.8
WP_000139447.1\|1930040_1930502_-	replication protein	A0A0U2JGJ0	Escherichia_phage	4.0e-79	90.2
WP_001262402.1\|1930494_1931538_-	hypothetical protein	A0A0U2RT81	Escherichia_phage	1.4e-82	65.1
1931478:1931491	attL	NA	NA	NA	NA
WP_000693878.1\|1931606_1932032_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_000747948.1\|1932015_1932258_-	hypothetical protein	H9C161	Pectobacterium_phage	4.8e-07	55.8
WP_001416688.1\|1932649_1932988_+	peptidase S24	H9C160	Pectobacterium_phage	1.9e-06	30.1
WP_000380316.1\|1933280_1933433_+	DUF1391 family protein	M4QQ57	Salicola_phage	5.1e-07	53.2
WP_000394548.1\|1933444_1934083_+	hypothetical protein	A0A2R2Z306	Escherichia_phage	2.5e-07	41.9
WP_001133037.1\|1934083_1934293_-	hypothetical protein	NA	NA	NA	NA
WP_000449175.1\|1934857_1935046_+	cell division inhibitor	NA	NA	NA	NA
WP_000199475.1\|1935042_1935231_+	DUF1482 family protein	NA	NA	NA	NA
WP_000102123.1\|1935323_1936568_+	exonuclease	H6WRX1	Salmonella_phage	1.4e-86	50.3
WP_001120551.1\|1937278_1937521_+	DinI-like family protein	Q687E4	Enterobacteria_phage	2.4e-27	83.3
WP_001171540.1\|1938483_1938864_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	7.1e-66	99.2
WP_000612591.1\|1938860_1939208_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_000998048.1\|1939257_1940796_+\|transposase	IS66-like element ISEc8 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.5e-300	100.0
WP_001121225.1\|1941378_1942029_-	type III secretion system effector NleG7	B6ETE1	Enterobacteria_phage	1.2e-121	99.1
WP_001131642.1\|1942738_1943314_-	DUF1076 domain-containing protein	H6WZN1	Escherichia_phage	4.1e-57	60.5
WP_001023362.1\|1943427_1943697_-\|tail	phage tail fiber C-terminal domain-containing protein	H6WZN0	Escherichia_phage	6.4e-45	98.9
WP_071805583.1\|1943698_1944922_-\|tail	prophage tail fiber N-terminal domain-containing protein	B6DZB7	Enterobacteria_phage	8.7e-81	92.6
WP_001230508.1\|1944986_1945586_-	Ail/Lom family outer membrane beta-barrel protein	A0A0P0ZE39	Stx2-converting_phage	1.2e-110	100.0
WP_001152180.1\|1949319_1949757_-\|tail	phage minor tail protein L	B6DZB1	Enterobacteria_phage	5.0e-63	100.0
WP_000807954.1\|1949756_1950098_-\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	5.1e-63	100.0
WP_064234971.1\|1950090_1953333_-\|tail	phage tail tape measure protein	A0A0P0ZDY0	Stx2-converting_phage	0.0e+00	99.4
WP_001453698.1\|1953385_1953595_-	DUF4035 domain-containing protein	A0A0P0ZDE6	Stx2-converting_phage	2.0e-33	100.0
WP_001030063.1\|1953690_1954065_-\|tail	phage tail assembly chaperone	A0A0N7KZA2	Stx2-converting_phage	7.8e-65	100.0
WP_001275508.1\|1954070_1954787_-\|tail	tail protein	A0A0P0ZD29	Stx2-converting_phage	2.9e-129	100.0
WP_000133388.1\|1954845_1955190_-	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
WP_000573374.1\|1955186_1955633_-	HK97 gp10 family phage protein	A0A0P0ZCD2	Stx2-converting_phage	8.1e-77	100.0
WP_001007901.1\|1955629_1955980_-\|head	phage head closure protein	A0A0P0ZCU6	Stx2-converting_phage	7.0e-60	100.0
WP_000126019.1\|1955989_1956316_-\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDA0	Stx2-converting_phage	9.2e-54	100.0
WP_001063099.1\|1958842_1959064_-	hypothetical protein	B6DZA0	Enterobacteria_phage	5.8e-36	100.0
WP_000173030.1\|1959108_1961046_-\|capsid	phage major capsid protein	B6ETE8	Enterobacteria_phage	0.0e+00	100.0
WP_038425863.1\|1961109_1962771_-\|terminase	terminase large subunit	A0A0P0ZD10	Stx2-converting_phage	0.0e+00	99.8
WP_000958422.1\|1962767_1963331_-\|terminase	terminase small subunit	A0A0N7KZJ8	Stx2-converting_phage	1.8e-89	99.5
WP_000279786.1\|1963620_1963986_-	HNH endonuclease	B6DZ96	Enterobacteria_phage	9.9e-65	99.2
WP_000095736.1\|1964027_1964255_+	DUF3950 domain-containing protein	A0A0P0ZE23	Stx2-converting_phage	1.7e-35	100.0
WP_012816791.1\|1964679_1964865_-	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.2e-18	100.0
WP_000539792.1\|1965092_1965239_-	hypothetical protein	A0A0P0ZE99	Stx2-converting_phage	2.6e-16	100.0
WP_001056806.1\|1965238_1965808_-	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	3.1e-105	100.0
WP_000992137.1\|1966078_1966612_-	lysozyme	B6DZ92	Enterobacteria_phage	3.5e-103	100.0
WP_000731259.1\|1966662_1967007_-	YdfR family protein	B6DZ91	Enterobacteria_phage	4.5e-59	100.0
WP_000284517.1\|1967011_1967227_-\|holin	class II holin family protein	A0A0P0ZC45	Stx2-converting_phage	4.5e-33	98.6
WP_072617007.1\|1967376_1969230_-	DUF1737 domain-containing protein	H6WZJ9	Escherichia_phage	0.0e+00	98.1
WP_000935548.1\|1970026_1971085_-	site-specific DNA-methyltransferase	S5MDR0	Escherichia_phage	1.1e-199	94.3
WP_000917750.1\|1971235_1971433_-	hypothetical protein	S5MQK8	Escherichia_phage	1.0e-28	98.5
WP_000640048.1\|1971674_1972205_-	DUF1133 family protein	A0A0U2S606	Escherichia_phage	9.3e-72	72.6
WP_000904166.1\|1972213_1972573_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	3.6e-35	60.9
WP_001302148.1\|1972585_1973632_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	4.2e-108	54.2
WP_072617008.1\|1973633_1973912_-	hypothetical protein	I6PCV7	Cronobacter_phage	6.3e-11	46.9
WP_001217394.1\|1973981_1974239_-	hypothetical protein	NA	NA	NA	NA
WP_000961820.1\|1974459_1974672_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	1.4e-15	70.0
WP_001449026.1\|1974950_1975709_-	AcfC family adhesin Paa	NA	NA	NA	NA
WP_001505071.1\|1976407_1976572_-	hypothetical protein	NA	NA	NA	NA
WP_149026311.1\|1976568_1977150_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	4.3e-78	79.7
WP_157825328.1\|1977336_1977879_-	replication protein	A0A0U2JGJ0	Escherichia_phage	1.5e-85	98.7
WP_000020556.1\|1977790_1978831_-	DNA-binding protein	A0A0U2RT81	Escherichia_phage	7.9e-91	87.2
WP_000705621.1\|1978802_1979354_-	hypothetical protein	NA	NA	NA	NA
WP_000912298.1\|1979337_1979565_-	transcriptional regulator	NA	NA	NA	NA
WP_000787428.1\|1979641_1980049_+	helix-turn-helix domain-containing protein	I6PD69	Cronobacter_phage	9.8e-29	49.6
WP_001240336.1\|1980314_1980614_+	hypothetical protein	NA	NA	NA	NA
WP_001171903.1\|1980686_1980905_+	hypothetical protein	NA	NA	NA	NA
WP_000394552.1\|1980927_1981335_+	hypothetical protein	A0A2R2Z306	Escherichia_phage	7.0e-11	37.8
WP_000920491.1\|1981312_1981546_-	hypothetical protein	NA	NA	NA	NA
WP_000449192.1\|1982104_1982293_+	cell division inhibition protein DicB	NA	NA	NA	NA
WP_001090200.1\|1982289_1982481_+	DUF1482 family protein	NA	NA	NA	NA
WP_000048551.1\|1982573_1985045_+	exonuclease	A0A192Y6E0	Salmonella_phage	1.1e-58	58.2
WP_000113189.1\|1985109_1985358_+	excisionase	NA	NA	NA	NA
WP_000113674.1\|1985335_1986466_+\|integrase	phage integrase Arm DNA-binding domain-containing protein	O21940	Phage_21	3.4e-103	51.4
1987345:1987358	attR	NA	NA	NA	NA

DBSCAN-SWA_8

2033162 : 2138528

106

Enterobacteria_phage(50.0%)

tail,lysis,head,portal,holin,transposase,tRNA,capsid,terminase,integrase,protease

attL 2070309:2070324|attR 2132431:2132446

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001299679.1\|2033162_2034419_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_001130692.1\|2034632_2035256_+	lipoprotein localization protein LolB	NA	NA	NA	NA
WP_001260332.1\|2035255_2036107_+	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase	NA	NA	NA	NA
WP_001298109.1\|2036257_2037205_+	ribose-phosphate diphosphokinase	A0A2K9L2G2	Tupanvirus	3.9e-44	37.8
WP_072617010.1\|2037329_2039009_+	C4-dicarboxylic acid transporter DauA	A0A2H4J153	uncultured_Caudovirales_phage	7.9e-24	23.8
WP_000823885.1\|2039063_2039342_-	stress-induced protein YchH	NA	NA	NA	NA
WP_000152933.1\|2039619_2040204_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_000505866.1\|2040320_2041412_+	redox-regulated ATPase YchF	NA	NA	NA	NA
WP_001303183.1\|2042255_2045141_+	pertactin family autotransporter	NA	NA	NA	NA
WP_001310261.1\|2045240_2047160_-	PTS-dependent dihydroxyacetone kinase operon transcriptional regulator DhaR	NA	NA	NA	NA
WP_000733713.1\|2047387_2048458_+	dihydroxyacetone kinase subunit DhaK	NA	NA	NA	NA
WP_001302889.1\|2048468_2049101_+	dihydroxyacetone kinase ADP-binding subunit DhaL	NA	NA	NA	NA
WP_001302890.1\|2049111_2050530_+	dihydroxyacetone kinase subunit DhaM	NA	NA	NA	NA
WP_000060146.1\|2052869_2053892_+	iron ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001223662.1\|2053891_2054872_+	iron ABC transporter permease	NA	NA	NA	NA
WP_000173324.1\|2054868_2055627_+	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	1.5e-14	29.7
WP_000576838.1\|2056445_2057300_+	ModD protein	NA	NA	NA	NA
WP_001302893.1\|2057325_2059296_+	TonB-dependent receptor	NA	NA	NA	NA
WP_000511315.1\|2059345_2059600_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_162829200.1\|2060448_2061661_+\|transposase	IS3 family transposase	Q6H9S6	Enterobacteria_phage	1.5e-170	100.0
WP_000051572.1\|2062559_2063474_+	muramoyltetrapeptide carboxypeptidase	NA	NA	NA	NA
WP_000340206.1\|2063569_2065306_+	potassium/proton antiporter	NA	NA	NA	NA
WP_162829348.1\|2065463_2066677_-\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	4.9e-169	99.7
WP_000197859.1\|2067014_2068085_-	catabolic alanine racemase DadX	NA	NA	NA	NA
WP_001266908.1\|2068094_2069393_-	D-amino acid dehydrogenase	NA	NA	NA	NA
WP_000190855.1\|2069722_2071255_+	SpoVR family protein	NA	NA	NA	NA
2070309:2070324	attL	NA	NA	NA	NA
WP_000234823.1\|2071306_2072026_-	fatty acid metabolism transcriptional regulator FadR	NA	NA	NA	NA
WP_000406391.1\|2072247_2073789_+	Na(+)/H(+) antiporter NhaB	NA	NA	NA	NA
WP_000943459.1\|2073934_2074465_+	disulfide bond formation protein DsbB	NA	NA	NA	NA
WP_000457644.1\|2074510_2075779_-	DNA polymerase V catalytic protein	I6RSM4	Salmonella_phage	3.0e-209	83.2
WP_000897378.1\|2075778_2076198_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	6.9e-38	62.1
WP_001304191.1\|2076570_2077482_+	hemolysin HlyE	NA	NA	NA	NA
WP_000807626.1\|2077688_2078150_-	YcgN family cysteine cluster protein	NA	NA	NA	NA
WP_000284277.1\|2078226_2078886_-	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_001295992.1\|2078957_2079251_-	YcgL domain-containing protein	NA	NA	NA	NA
WP_000874954.1\|2079262_2079421_-	hypothetical protein	NA	NA	NA	NA
WP_000695220.1\|2079491_2079893_+	PPC domain-containing protein	NA	NA	NA	NA
WP_001056834.1\|2079995_2080364_-	hypothetical protein	NA	NA	NA	NA
WP_000072536.1\|2080883_2081579_+	septum site-determining protein MinC	NA	NA	NA	NA
WP_000101055.1\|2081602_2082415_+	septum site-determining protein MinD	NA	NA	NA	NA
WP_001185665.1\|2082418_2082685_+	cell division topological specificity factor MinE	NA	NA	NA	NA
WP_000361110.1\|2083923_2084508_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001201843.1\|2085006_2085960_+\|protease	omptin family outer membrane protease OmpT	NA	NA	NA	NA
WP_001226373.1\|2086146_2087631_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_000998048.1\|2087933_2089472_-\|transposase	IS66-like element ISEc8 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.5e-300	100.0
WP_000612591.1\|2089521_2089869_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_001171540.1\|2089865_2090246_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	7.1e-66	99.2
WP_000937476.1\|2090321_2090570_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	1.7e-12	76.5
WP_000239881.1\|2090626_2091295_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000134810.1\|2091792_2091975_+	general stress protein	NA	NA	NA	NA
WP_001166090.1\|2092053_2092554_+	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_001079482.1\|2092590_2093097_+	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_000488340.1\|2093115_2094006_+	manganese catalase family protein	NA	NA	NA	NA
WP_000885630.1\|2094125_2094707_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	6.1e-101	93.7
WP_000279120.1\|2094706_2097622_-\|tail	phage tail protein	Q6H9S9	Enterobacteria_phage	1.1e-57	98.3
WP_001230336.1\|2097686_2098286_-	Ail/Lom family outer membrane beta-barrel protein	A0A291AWV3	Escherichia_phage	3.0e-111	99.5
WP_072617011.1\|2098352_2101751_-	host specificity protein J	K7PKJ2	Enterobacteria_phage	0.0e+00	90.6
WP_000090920.1\|2101811_2102444_-\|tail	tail assembly protein	A0A2R9YJH6	Escherichia_phage	1.7e-96	99.5
WP_000194779.1\|2102380_2103124_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	2.0e-149	97.6
WP_001152612.1\|2103129_2103828_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	2.1e-132	98.7
WP_000459457.1\|2104413_2104848_-\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	6.9e-65	100.0
WP_000479161.1\|2104829_2105252_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	2.4e-70	96.4
WP_001143002.1\|2105267_2106008_-\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	8.3e-127	95.9
WP_000683105.1\|2106015_2106411_-\|tail	tail protein	A0A0K2FIF4	Enterobacteria_phage	1.0e-70	100.0
WP_072617012.1\|2106996_2107350_-\|head,tail	head-tail joining protein	A0A2R9YJJ5	Escherichia_phage	2.2e-61	98.3
WP_000158906.1\|2107361_2107760_-	DNA-packaging protein FI	A0A0K2FIR1	Enterobacteria_phage	3.5e-63	98.5
WP_000063265.1\|2107801_2108827_-\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	8.7e-191	98.8
WP_001295978.1\|2108882_2109215_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	3.8e-55	99.1
WP_000123254.1\|2109224_2110544_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	3.4e-232	98.2
WP_001301524.1\|2110524_2112126_-\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	1.4e-307	98.7
WP_000198153.1\|2112122_2112329_-	gpW family protein	A0A2R9YJL2	Escherichia_phage	2.2e-29	98.5
WP_001027365.1\|2112325_2114251_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.2
WP_000453564.1\|2114225_2114771_-	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	2.6e-93	97.8
WP_001300120.1\|2115159_2115354_+	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	1.5e-27	98.4
WP_001031427.1\|2115518_2115725_-	hypothetical protein	A0A0K2FJ18	Enterobacteria_phage	5.8e-30	100.0
WP_000079504.1\|2116010_2116421_+	DUF1398 domain-containing protein	C6ZCX4	Enterobacteria_phage	2.7e-71	98.5
WP_000738495.1\|2116712_2117006_+	serum resistance lipoprotein Bor	K7PL54	Enterobacteria_phage	1.5e-47	99.0
WP_010917798.1\|2117096_2117279_-\|lysis	prophage lysis lipoprotein RzoD	K7PHU6	Enterobacteria_phage	4.7e-15	93.3
WP_001180487.1\|2117495_2117972_-	glycoside hydrolase family protein	K7PKV2	Enterobacteria_phage	4.3e-84	95.6
WP_000544528.1\|2117958_2118264_-\|holin	phage holin family protein	A0A286N2Q5	Klebsiella_phage	7.0e-40	87.6
WP_001097228.1\|2118585_2119275_-	Q antiterminator encoded by prophage CP-933P	I6PDF8	Cronobacter_phage	1.7e-57	48.9
WP_000971093.1\|2119271_2119412_-	YlcG family protein	K7PHH3	Enterobacteria_phage	7.7e-10	71.1
WP_001099695.1\|2119408_2119771_-	crossover junction endodeoxyribonuclease RusA	K7PM48	Enterobacteria_phage	7.3e-60	95.7
WP_000774504.1\|2119767_2120058_-	DUF1364 domain-containing protein	K7PGZ6	Enterobacteria_phage	2.8e-46	92.7
WP_000224907.1\|2120050_2120221_-	hypothetical protein	K7P7K0	Enterobacteria_phage	5.3e-13	67.9
WP_001053040.1\|2120220_2120676_-	recombination protein NinB	I6PD71	Cronobacter_phage	8.6e-58	64.9
WP_000709077.1\|2121177_2122704_-	recombinase family protein	Q3HQV4	Burkholderia_phage	1.2e-31	31.1
WP_001302833.1\|2122761_2122884_-	hypothetical protein	NA	NA	NA	NA
WP_001070446.1\|2122948_2123281_-	SMR family multidrug efflux protein EmrE	NA	NA	NA	NA
WP_000145915.1\|2123348_2123651_-	protein ren	A0A0N6WES4	Escherichia_phage	1.1e-42	95.7
WP_000788869.1\|2123647_2124349_-	Replication protein P	A0A0P0ZD31	Stx2-converting_phage	1.3e-129	99.6
WP_000088655.1\|2125273_2125510_+	excisionase	NA	NA	NA	NA
WP_000741454.1\|2125499_2126642_+\|integrase	phage integrase Arm DNA-binding domain-containing protein	O21940	Phage_21	8.1e-206	100.0
WP_000444477.1\|2126755_2128006_-	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	3.8e-23	100.0
WP_001248690.1\|2128177_2128831_+	23S rRNA pseudouridine(2457) synthase RluE	NA	NA	NA	NA
WP_000476093.1\|2128840_2129302_+	phosphatase NudJ	NA	NA	NA	NA
WP_001301861.1\|2129355_2130462_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_001301618.1\|2130497_2131139_+	high frequency lysogenization protein HflD	NA	NA	NA	NA
WP_000423729.1\|2131142_2132513_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.2e-108	44.9
2132431:2132446	attR	NA	NA	NA	NA
WP_001265474.1\|2132681_2133353_+	two-component system response regulator PhoP	NA	NA	NA	NA
WP_000735407.1\|2133352_2134813_+	two-component system sensor histidine kinase PhoQ	NA	NA	NA	NA
WP_000133424.1\|2135413_2135695_-	hypothetical protein	NA	NA	NA	NA
WP_000835281.1\|2135950_2136493_-\|terminase	terminase small subunit	O64316	Escherichia_phage	1.8e-33	44.2
WP_000224603.1\|2136698_2137112_-	hypothetical protein	NA	NA	NA	NA
WP_000380883.1\|2137124_2137460_-\|head	head decoration protein	NA	NA	NA	NA
WP_000907465.1\|2137472_2138528_-\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	1.5e-68	43.3

DBSCAN-SWA_9

2144619 : 2194931

Stx2-converting_phage(37.21%)

tail,head,holin,transposase,capsid,terminase,integrase

attL 2144027:2144040|attR 2153323:2153336

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2144027:2144040	attL	NA	NA	NA	NA
WP_000085256.1\|2144619_2145849_-\|integrase	site-specific integrase	A0A2H4JB45	uncultured_Caudovirales_phage	3.8e-132	56.1
WP_001301987.1\|2146097_2147219_+	[50S ribosomal protein L16]-arginine 3-hydroxylase	NA	NA	NA	NA
WP_000359446.1\|2147267_2148494_-	peptidase T	NA	NA	NA	NA
WP_000531594.1\|2148743_2149880_+	spermidine/putrescine ABC transporter ATP-binding protein PotA	Q6GZ03	Mycoplasma_phage	5.5e-29	39.8
WP_000799385.1\|2149863_2150727_+	spermidine/putrescine ABC transporter permease PotB	Q6GZ02	Mycoplasma_phage	6.7e-11	28.7
WP_000938118.1\|2151090_2152452_+	type III secretion system effector EspK	Q9MBM1	Phage_Gifsy-1	1.4e-50	29.2
WP_001303921.1\|2152512_2152788_+	hypothetical protein	NA	NA	NA	NA
WP_001301984.1\|2155096_2158498_-	type III secretion system effector EspN	A0A0N7KZG3	Stx2-converting_phage	1.7e-219	39.2
2153323:2153336	attR	NA	NA	NA	NA
WP_001301673.1\|2159088_2161437_-	type III secretion system effector E3 ubiquitin ligase NleL	NA	NA	NA	NA
WP_115801847.1\|2161456_2161546_-	hypothetical protein	NA	NA	NA	NA
WP_071526731.1\|2161558_2161795_-\|tail	tail assembly protein	B6ETG3	Enterobacteria_phage	2.8e-20	80.3
WP_000967274.1\|2161740_2162478_-\|tail	phage tail protein	B6ETG2	Enterobacteria_phage	9.1e-150	99.6
WP_000835336.1\|2162531_2163410_-	phage repressor protein/antirepressor Ant	I6R977	Salmonella_phage	2.5e-93	77.2
WP_010904626.1\|2163712_2163823_-	Arc family DNA-binding protein	NA	NA	NA	NA
WP_000170104.1\|2163932_2164187_+	Arc family DNA-binding protein	NA	NA	NA	NA
WP_072617013.1\|2164203_2164902_-\|tail	phage minor tail protein L	Q6H9T5	Enterobacteria_phage	2.4e-131	98.3
WP_000807954.1\|2164901_2165243_-\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	5.1e-63	100.0
WP_072617014.1\|2165235_2168478_-\|tail	phage tail tape measure protein	A0A0P0ZDY0	Stx2-converting_phage	0.0e+00	98.5
WP_001453698.1\|2168530_2168740_-	DUF4035 domain-containing protein	A0A0P0ZDE6	Stx2-converting_phage	2.0e-33	100.0
WP_001030063.1\|2168835_2169210_-\|tail	phage tail assembly chaperone	A0A0N7KZA2	Stx2-converting_phage	7.8e-65	100.0
WP_001275508.1\|2169215_2169932_-\|tail	tail protein	A0A0P0ZD29	Stx2-converting_phage	2.9e-129	100.0
WP_000133388.1\|2169990_2170335_-	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
WP_000573374.1\|2170331_2170778_-	HK97 gp10 family phage protein	A0A0P0ZCD2	Stx2-converting_phage	8.1e-77	100.0
WP_001007901.1\|2170774_2171125_-\|head	phage head closure protein	A0A0P0ZCU6	Stx2-converting_phage	7.0e-60	100.0
WP_000126019.1\|2171134_2171461_-\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDA0	Stx2-converting_phage	9.2e-54	100.0
WP_001063099.1\|2173987_2174209_-	hypothetical protein	B6DZA0	Enterobacteria_phage	5.8e-36	100.0
WP_072617015.1\|2174253_2176191_-\|capsid	phage major capsid protein	B6ETE8	Enterobacteria_phage	0.0e+00	97.7
WP_038425863.1\|2176254_2177916_-\|terminase	terminase large subunit	A0A0P0ZD10	Stx2-converting_phage	0.0e+00	99.8
WP_000958422.1\|2177912_2178476_-\|terminase	terminase small subunit	A0A0N7KZJ8	Stx2-converting_phage	1.8e-89	99.5
WP_000279786.1\|2178765_2179131_-	HNH endonuclease	B6DZ96	Enterobacteria_phage	9.9e-65	99.2
WP_000095736.1\|2179172_2179400_+	DUF3950 domain-containing protein	A0A0P0ZE23	Stx2-converting_phage	1.7e-35	100.0
WP_012816791.1\|2179824_2180010_-	membrane protein	A0A0P0ZCT3	Stx2-converting_phage	1.2e-18	100.0
WP_000539792.1\|2180237_2180384_-	hypothetical protein	A0A0P0ZE99	Stx2-converting_phage	2.6e-16	100.0
WP_001056806.1\|2180383_2180953_-	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	3.1e-105	100.0
WP_000992137.1\|2181223_2181757_-	lysozyme	B6DZ92	Enterobacteria_phage	3.5e-103	100.0
WP_000731204.1\|2181807_2182152_-	YdfR family protein	B6DZ91	Enterobacteria_phage	1.7e-58	99.1
WP_024165672.1\|2182156_2182372_-\|holin	class II holin family protein	Q6H9V8	Enterobacteria_phage	7.7e-33	98.6
WP_072617016.1\|2182811_2184662_-	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	98.4
WP_001303509.1\|2185140_2185569_-	tellurite resistance protein	H6WZJ6	Escherichia_phage	4.4e-64	97.8
WP_001059381.1\|2186207_2186897_-	antiterminator	I6PDF8	Cronobacter_phage	4.0e-59	51.1
WP_001217455.1\|2186893_2187253_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	5.9e-38	67.5
WP_001265161.1\|2187265_2188315_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.4e-108	53.7
WP_012779366.1\|2188316_2188595_-	hypothetical protein	I6PCV7	Cronobacter_phage	5.7e-12	48.4
WP_000887477.1\|2188762_2188975_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	3.1e-18	68.6
WP_001278450.1\|2189163_2189268_-	hypothetical protein	NA	NA	NA	NA
WP_000206793.1\|2189383_2189968_-	DUF551 domain-containing protein	A0A0P0ZD75	Stx2-converting_phage	1.9e-33	84.8
WP_001118159.1\|2190024_2190420_-	DUF977 family protein	A0A0U2QQN3	Escherichia_phage	7.8e-31	51.4
WP_000788938.1\|2191230_2191971_-	ATP-binding protein	A0A088CBP4	Shigella_phage	4.6e-125	90.2
WP_000095669.1\|2191977_2192940_-	helix-turn-helix domain-containing protein	U5P0A0	Shigella_phage	4.8e-82	57.3
WP_000693943.1\|2192962_2193388_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_072617017.1\|2193384_2193669_-	transcriptional regulator	K7PHA1	Enterobacteria_phage	5.2e-05	35.4
WP_162829202.1\|2193717_2194931_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	7.6e-170	100.0

DBSCAN-SWA_10

2507278 : 2559492

Enterobacteria_phage(60.0%)

tRNA,tail,integrase,transposase

attL 2500502:2500517|attR 2559571:2559586

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2500502:2500517	attL	NA	NA	NA	NA
WP_001025318.1\|2507278_2509012_+\|tRNA	arginine--tRNA ligase	A0A2K9L6Z2	Tupanvirus	4.0e-87	33.7
WP_001302043.1\|2509188_2509677_+	lysozyme inhibitor LprI family protein	NA	NA	NA	NA
WP_001259575.1\|2509796_2510189_-	flagellar protein FlhE	NA	NA	NA	NA
WP_000067016.1\|2510188_2512267_-	flagellar biosynthesis protein FlhA	NA	NA	NA	NA
WP_001278932.1\|2512259_2513408_-	flagellar type III secretion system protein FlhB	NA	NA	NA	NA
WP_000983602.1\|2513609_2514254_-	protein phosphatase CheZ	NA	NA	NA	NA
WP_000763867.1\|2514264_2514654_-	chemotaxis response regulator CheY	A0A2K9L4R0	Tupanvirus	1.3e-06	32.0
WP_000036370.1\|2514668_2515718_-	protein-glutamate methylesterase/protein glutamine deamidase	Q56AR1	Bacillus_thuringiensis_phage	1.0e-05	32.8
WP_000204340.1\|2515720_2516581_-	protein-glutamate O-methyltransferase CheR	NA	NA	NA	NA
WP_000483251.1\|2516599_2518201_-	methyl-accepting chemotaxis protein IV	A0A2H4J162	uncultured_Caudovirales_phage	5.4e-14	29.8
WP_072617026.1\|2518246_2519686_-	Tar ligand binding domain-containing protein	NA	NA	NA	NA
WP_000147302.1\|2519828_2520332_-	chemotaxis protein CheW	NA	NA	NA	NA
WP_001322280.1\|2520352_2522317_-	chemotaxis protein CheA	NA	NA	NA	NA
WP_000795630.1\|2522321_2523248_-	flagellar motor protein MotB	NA	NA	NA	NA
WP_000906325.1\|2523244_2524132_-	flagellar motor stator protein MotA	NA	NA	NA	NA
WP_072617027.1\|2524258_2524837_-	flagellar transcriptional regulator FlhC	NA	NA	NA	NA
WP_001302091.1\|2524839_2525190_-	flagellar transcriptional regulator FlhD	NA	NA	NA	NA
WP_000122432.1\|2525969_2526398_+	universal stress protein UspC	NA	NA	NA	NA
WP_001295646.1\|2526404_2527829_-	alpha,alpha-trehalose-phosphate synthase	NA	NA	NA	NA
WP_001302045.1\|2527803_2528604_-	trehalose-phosphatase	NA	NA	NA	NA
WP_001302082.1\|2528770_2529757_-	arabinose ABC transporter permease AraH	NA	NA	NA	NA
WP_001187819.1\|2529771_2531286_-	arabinose ABC transporter ATP binding protein AraG	A0A2H4PQG7	Staphylococcus_phage	4.3e-13	27.1
WP_000548680.1\|2531355_2532345_-	arabinose ABC transporter substrate-binding protein AraF	NA	NA	NA	NA
WP_000179469.1\|2533141_2533645_+	non-heme ferritin-like protein	NA	NA	NA	NA
WP_000084172.1\|2533724_2533976_-	DUF2766 domain-containing protein	NA	NA	NA	NA
WP_010723106.1\|2534090_2534177_-	stress response protein AzuC	NA	NA	NA	NA
WP_001237873.1\|2534438_2534762_+	YecR-like lipofamily protein	NA	NA	NA	NA
WP_000917208.1\|2534932_2535430_+	non-heme ferritin	NA	NA	NA	NA
WP_000377224.1\|2535466_2535706_-	YecH family protein	NA	NA	NA	NA
WP_000797566.1\|2535897_2537109_+	tyrosine transporter TyrP	NA	NA	NA	NA
WP_000847882.1\|2537170_2537836_-	UPF0149 family protein YecA	NA	NA	NA	NA
WP_001300279.1\|2538192_2539194_-\|integrase	tyrosine-type recombinase/integrase	Q94N03	Haemophilus_virus	4.2e-105	58.5
WP_000865208.1\|2539199_2539547_-	DUF2511 domain-containing protein	NA	NA	NA	NA
WP_000290345.1\|2539576_2540227_-	hypothetical protein	NA	NA	NA	NA
WP_000786773.1\|2540242_2540647_-	transcriptional regulator	Q6QID2	Burkholderia_phage	2.7e-23	53.8
WP_001673482.1\|2540737_2540875_-	hypothetical protein	NA	NA	NA	NA
WP_000014504.1\|2540946_2541150_+	DNA-binding protein	P79674	Haemophilus_phage	3.1e-07	45.2
WP_000739029.1\|2541171_2541522_+	DUF4761 family protein	A0A0A7NV42	Enterobacteria_phage	8.6e-50	81.9
WP_000159449.1\|2541532_2541811_+	hypothetical protein	A0A0A7NRX5	Enterobacteria_phage	4.8e-35	80.4
WP_000514287.1\|2541822_2542065_+	DUF4754 family protein	A0A0A7NQ71	Enterobacteria_phage	1.2e-37	98.8
WP_000021655.1\|2542061_2542175_+	hypothetical protein	A0A0A7NPW7	Enterobacteria_phage	6.2e-10	100.0
WP_000991913.1\|2542267_2542684_+	hypothetical protein	NA	NA	NA	NA
WP_000985157.1\|2542707_2542911_+	hypothetical protein	A0A0A7NPS8	Enterobacteria_phage	2.5e-25	83.6
WP_000153707.1\|2542907_2543174_+	winged helix-turn-helix transcriptional regulator	A0A0A7NV47	Enterobacteria_phage	3.1e-31	77.3
WP_000104305.1\|2543170_2543470_+	hypothetical protein	A0A0A7NRX6	Enterobacteria_phage	1.6e-41	89.9
WP_001310314.1\|2543481_2544099_+	ash family protein	S5MQL6	Escherichia_phage	2.1e-06	46.2
WP_000599379.1\|2544095_2544461_+	hypothetical protein	A0A0A7NRY1	Enterobacteria_phage	6.6e-61	96.7
WP_000123463.1\|2544467_2547290_+	replication endonuclease	A0A0A7NQ77	Enterobacteria_phage	0.0e+00	97.7
WP_000686523.1\|2547366_2548326_+	plasmid segregation protein ParM	A0A0A7NPX4	Enterobacteria_phage	1.2e-178	99.1
WP_000211280.1\|2548330_2548645_+	plasmid partitioning/stability family protein	A0A0A7NPT5	Enterobacteria_phage	1.1e-19	52.9
WP_001310336.1\|2549736_2550267_+\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	3.5e-87	88.0
WP_000954203.1\|2550310_2550883_-	serine acetyltransferase	A0A1L2JYI5	Streptococcus_phage	1.0e-07	34.4
WP_000979955.1\|2551039_2551528_-\|tail	phage tail protein	A0A0A7NV65	Enterobacteria_phage	1.0e-85	100.0
WP_000333495.1\|2554330_2554486_-\|tail	GpE family phage tail protein	A0A0A7NQ96	Enterobacteria_phage	8.8e-23	100.0
WP_000665314.1\|2554494_2554860_-\|tail	tail protein	A0A0A7NPZ0	Enterobacteria_phage	1.7e-56	98.3
WP_000290456.1\|2554914_2555427_-\|tail	phage major tail tube protein	A0A0A7NPV8	Enterobacteria_phage	2.1e-92	99.4
WP_000005444.1\|2555426_2556611_-\|tail	phage tail sheath family protein	A0A0A7NV69	Enterobacteria_phage	1.7e-219	96.7
WP_000132765.1\|2556768_2557092_+	phage late control D family protein	A0A0A7NQ97	Enterobacteria_phage	2.1e-42	97.8
WP_162829202.1\|2557196_2558409_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	7.6e-170	100.0
WP_050543672.1\|2558412_2559492_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	3.1e-37	35.4
2559571:2559586	attR	NA	NA	NA	NA

DBSCAN-SWA_11

2617010 : 2687931

Escherichia_phage(34.09%)

tail,head,portal,holin,transposase,capsid,terminase,integrase

attL 2632811:2632826|attR 2688420:2688435

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001023406.1\|2617010_2617280_-\|tail	phage tail fiber C-terminal domain-containing protein	Q6H9S8	Enterobacteria_phage	2.4e-44	97.8
WP_072617028.1\|2617281_2618595_-\|tail	phage tail protein	A0A0P0ZE15	Stx2-converting_phage	1.3e-77	97.3
WP_001230508.1\|2618659_2619259_-	Ail/Lom family outer membrane beta-barrel protein	A0A0P0ZE39	Stx2-converting_phage	1.2e-110	100.0
WP_072617029.1\|2619326_2622809_-	host specificity protein J	A0A0P0ZDT4	Stx2-converting_phage	0.0e+00	99.1
WP_054191786.1\|2623623_2624367_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	2.1e-146	96.8
WP_072617001.1\|2624377_2625076_-\|tail	phage minor tail protein L	A0A0N7KZH0	Stx2-converting_phage	1.2e-130	98.7
WP_000847298.1\|2625075_2625405_-\|tail	phage tail protein	Q687F2	Enterobacteria_phage	4.3e-59	100.0
WP_000082473.1\|2625401_2627981_-\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	79.9
WP_072617030.1\|2627961_2628375_-\|tail	phage tail assembly protein T	S5MDP5	Escherichia_phage	4.6e-42	81.2
WP_000479117.1\|2628401_2628833_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	2.4e-41	68.1
WP_029208397.1\|2628846_2629587_-\|tail	phage tail protein	Q687F6	Enterobacteria_phage	3.6e-130	98.0
WP_001301534.1\|2629568_2629835_-\|capsid	major capsid protein	NA	NA	NA	NA
WP_000256723.1\|2629892_2630240_-\|head	head decoration protein	C6ZCY1	Enterobacteria_phage	2.6e-22	58.1
WP_001254002.1\|2630276_2631782_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	1.2e-100	54.2
WP_000831796.1\|2631771_2633364_-\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	8.7e-182	60.5
2632811:2632826	attL	NA	NA	NA	NA
WP_000259002.1\|2633360_2633567_-\|head,tail	head-tail joining protein	K7PM10	Enterobacteria_phage	7.9e-11	56.9
WP_000235436.1\|2635436_2635946_-\|terminase	terminase small subunit	A0A1I9KFT4	Aeromonas_phage	1.6e-12	32.7
WP_001299328.1\|2636340_2636565_+	YlcI/YnfO family protein	A0A0K2FIR8	Escherichia_phage	4.1e-21	92.7
WP_001302690.1\|2636646_2636961_-	PerC family transcriptional regulator	NA	NA	NA	NA
WP_001208680.1\|2637487_2637673_-	membrane protein	A0A1U9AJA4	Stx1_converting_phage	1.7e-20	80.3
WP_001280929.1\|2637900_2638032_-	hypothetical protein	A0A0N7BYT9	Escherichia_phage	9.4e-10	88.4
WP_001303555.1\|2638044_2638227_-	hypothetical protein	NA	NA	NA	NA
WP_000992126.1\|2638382_2638916_-	lysozyme	A0A0N7KZF9	Stx2-converting_phage	1.4e-99	97.7
WP_000731204.1\|2638966_2639311_-	YdfR family protein	B6DZ91	Enterobacteria_phage	1.7e-58	99.1
WP_024165672.1\|2639315_2639531_-\|holin	class II holin family protein	Q6H9V8	Enterobacteria_phage	7.7e-33	98.6
WP_162829202.1\|2639843_2641056_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	7.6e-170	100.0
WP_000023257.1\|2641138_2642989_-	SASA family carbohydrate esterase	B6DZ89	Enterobacteria_phage	0.0e+00	96.4
WP_001059369.1\|2644527_2645217_-	antiterminator	I6PDF8	Cronobacter_phage	1.5e-58	51.1
WP_000904141.1\|2645213_2645573_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	1.5e-36	64.9
WP_001265075.1\|2645585_2646635_-	DUF968 domain-containing protein	U5P0K4	Shigella_phage	1.3e-109	54.9
WP_001310296.1\|2646636_2646915_-	hypothetical protein	I6PCV7	Cronobacter_phage	1.3e-11	48.4
WP_000902687.1\|2647082_2647295_-	type I toxin-antitoxin system Hok family toxin	A0A0U2QV81	Escherichia_phage	7.6e-25	90.0
WP_001278461.1\|2647481_2647586_-	hypothetical protein	NA	NA	NA	NA
WP_000137954.1\|2647695_2648259_-	hypothetical protein	H6WZG0	Escherichia_phage	4.5e-48	94.9
WP_000111243.1\|2648385_2648697_-	hypothetical protein	A0A222YY67	Escherichia_phage	2.4e-51	83.5
WP_001414276.1\|2648693_2648846_-	hypothetical protein	NA	NA	NA	NA
WP_001290006.1\|2648878_2649235_-	hypothetical protein	A0A222YY85	Escherichia_phage	3.1e-15	65.8
WP_000702797.1\|2649231_2649456_-	hypothetical protein	A0A1B5FPG2	Escherichia_phage	3.6e-09	42.3
WP_000450610.1\|2649477_2650176_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	1.6e-71	59.5
WP_072143023.1\|2650210_2650753_-	replication protein	A0A0U2JGJ0	Escherichia_phage	6.4e-84	96.7
WP_001262409.1\|2650664_2651702_-	hypothetical protein	A0A0U2RT81	Escherichia_phage	1.1e-87	68.3
WP_000693816.1\|2651770_2652196_-	Rha family transcriptional regulator	NA	NA	NA	NA
WP_001261752.1\|2652192_2652420_-	cell division protein	NA	NA	NA	NA
WP_000444607.1\|2652517_2653162_+	LexA family transcriptional regulator	A0A1P8DTH0	Proteus_phage	2.8e-06	24.9
WP_000367376.1\|2653436_2653589_+	DUF1391 family protein	M4QQ57	Salicola_phage	8.7e-07	53.2
WP_000449168.1\|2654069_2654258_+	cell division inhibitor	NA	NA	NA	NA
WP_000199485.1\|2654254_2654443_+	DUF1482 family protein	NA	NA	NA	NA
WP_000034457.1\|2654538_2657010_+	exonuclease	A0A192Y6E0	Salmonella_phage	8.8e-56	56.6
WP_000094838.1\|2657068_2657272_+	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_000533600.1\|2657271_2658294_+\|integrase	tyrosine-type recombinase/integrase	A0A192Y7M7	Salmonella_phage	2.0e-99	57.4
WP_001302302.1\|2658529_2659327_+	DgsA anti-repressor MtfA	NA	NA	NA	NA
WP_014714124.1\|2659816_2667799_+	inverse autotransporter adhesin-like protein YeeJ	NA	NA	NA	NA
WP_000480501.1\|2668060_2669113_-	glycosyltransferase family 9 protein	NA	NA	NA	NA
WP_000378596.1\|2669426_2670743_+	shikimate transporter	NA	NA	NA	NA
WP_001060244.1\|2670844_2672299_+	AMP nucleosidase	NA	NA	NA	NA
WP_000532909.1\|2672641_2673358_+	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_122989775.1\|2673983_2675627_-	toxic metabolite efflux MATE transporter YeeO	NA	NA	NA	NA
WP_001011000.1\|2675744_2676695_-	HTH-type transcriptional regulator Cbl	NA	NA	NA	NA
WP_001011474.1\|2676796_2677714_-	nitrogen assimilation transcriptional regulator NAC	NA	NA	NA	NA
WP_000986334.1\|2678170_2679106_-	L,D-transpeptidase	NA	NA	NA	NA
WP_001193830.1\|2679167_2680247_-	nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	NA	NA	NA	NA
WP_001295633.1\|2680258_2681002_-	adenosylcobinamide-GDP ribazoletransferase	NA	NA	NA	NA
WP_000973176.1\|2680998_2681544_-	bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase	NA	NA	NA	NA
WP_001171554.1\|2681905_2682286_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	1.4e-66	100.0
WP_000612591.1\|2682282_2682630_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_000998048.1\|2682679_2684218_+\|transposase	IS66-like element ISEc8 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.5e-300	100.0
WP_162829348.1\|2686718_2687931_+\|transposase	IS3 family transposase	H6WZH1	Escherichia_phage	4.9e-169	99.7
2688420:2688435	attR	NA	NA	NA	NA

DBSCAN-SWA_12

2698740 : 2757128

Stx2-converting_phage(59.49%)

tail,lysis,head,portal,holin,transposase,capsid,terminase,integrase,protease

attL 2703034:2703048|attR 2764271:2764285

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001303036.1\|2698740_2699907_-	serine-type D-Ala-D-Ala carboxypeptidase DacD	B6DZZ7	Stx2-converting_phage	4.5e-228	99.7
WP_001121226.1\|2701229_2701880_+	type III secretion system effector NleG7	B6ETE1	Enterobacteria_phage	4.1e-122	99.5
WP_000491542.1\|2702104_2702980_-	hypothetical protein	A0A0P0ZCT1	Stx2-converting_phage	1.5e-162	100.0
2703034:2703048	attL	NA	NA	NA	NA
WP_001023452.1\|2703120_2703390_-\|tail	phage tail fiber C-terminal domain-containing protein	Q687E5	Enterobacteria_phage	6.4e-45	100.0
WP_070080209.1\|2703391_2704705_-\|tail	phage tail protein	A0A0P0ZCC1	Stx2-converting_phage	3.3e-78	97.5
WP_001230509.1\|2704769_2705369_-	Ail/Lom family outer membrane beta-barrel protein	A0A0P0ZE39	Stx2-converting_phage	3.3e-110	99.5
WP_072617032.1\|2705436_2708919_-	host specificity protein J	A0A0P0ZDT4	Stx2-converting_phage	0.0e+00	99.1
WP_122994717.1\|2709155_2709788_-\|tail	tail assembly protein	A0A0P0ZDX8	Stx2-converting_phage	3.1e-106	99.0
WP_001457600.1\|2709733_2710471_-\|tail	phage tail protein	A0A0P0ZDJ9	Stx2-converting_phage	9.1e-150	99.6
WP_001428824.1\|2710525_2711449_-	phage antirepressor Ant	A0A0N7KZK0	Stx2-converting_phage	1.3e-177	100.0
WP_001154345.1\|2711519_2711693_-	Arc family DNA-binding protein	A0A0P0ZC65	Stx2-converting_phage	3.4e-23	100.0
WP_001302649.1\|2711800_2712121_+	Arc family DNA-binding protein	A0A0P0ZBD1	Stx2-converting_phage	3.0e-49	100.0
WP_001179516.1\|2712137_2712836_-\|tail	phage minor tail protein L	A0A0P0ZD82	Stx2-converting_phage	1.5e-133	100.0
WP_000807954.1\|2712835_2713177_-\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	5.1e-63	100.0
WP_064234948.1\|2713169_2716412_-\|tail	phage tail tape measure protein	A0A0P0ZE78	Stx2-converting_phage	0.0e+00	95.8
WP_001453698.1\|2716464_2716674_-	DUF4035 domain-containing protein	A0A0P0ZDE6	Stx2-converting_phage	2.0e-33	100.0
WP_001030063.1\|2716769_2717144_-\|tail	phage tail assembly chaperone	A0A0N7KZA2	Stx2-converting_phage	7.8e-65	100.0
WP_001275508.1\|2717149_2717866_-\|tail	tail protein	A0A0P0ZD29	Stx2-converting_phage	2.9e-129	100.0
WP_000133388.1\|2717924_2718269_-	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
WP_000573374.1\|2718265_2718712_-	HK97 gp10 family phage protein	A0A0P0ZCD2	Stx2-converting_phage	8.1e-77	100.0
WP_001007901.1\|2718708_2719059_-\|head	phage head closure protein	A0A0P0ZCU6	Stx2-converting_phage	7.0e-60	100.0
WP_000126019.1\|2719068_2719395_-\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZDA0	Stx2-converting_phage	9.2e-54	100.0
WP_149026313.1\|2719474_2721976_-\|portal	phage portal protein	A0A0P0ZDD0	Stx2-converting_phage	0.0e+00	99.9
WP_001063099.1\|2721921_2722143_-	hypothetical protein	B6DZA0	Enterobacteria_phage	5.8e-36	100.0
WP_072617033.1\|2722187_2724125_-\|capsid	phage major capsid protein	B6ETE8	Enterobacteria_phage	0.0e+00	99.8
WP_072617034.1\|2724188_2725850_-\|terminase	terminase large subunit	A0A0P0ZEI4	Stx2-converting_phage	0.0e+00	99.8
WP_000958365.1\|2725846_2726410_-\|terminase	terminase small subunit	A0A0P0ZD56	Stx2-converting_phage	8.9e-89	98.9
WP_001303046.1\|2726700_2727066_-	HNH endonuclease	A0A0P0ZCH0	Stx2-converting_phage	2.0e-65	100.0
WP_000095749.1\|2727107_2727335_+	DUF3950 domain-containing protein	A0A0P0ZCA1	Stx2-converting_phage	3.9e-35	100.0
WP_001283921.1\|2727797_2728055_-	hypothetical protein	A0A0P0ZBT1	Stx2-converting_phage	5.0e-39	100.0
WP_000839224.1\|2728051_2728549_-	KilA-N domain-containing protein	A0A0P0ZBU2	Stx2-converting_phage	3.6e-94	100.0
WP_000092318.1\|2728751_2729189_-\|lysis	lysis protein	A0A0P0ZBQ9	Stx2-converting_phage	2.0e-72	100.0
WP_000075132.1\|2729185_2729683_-	lysozyme RrrD	A0A0N7KZA0	Stx2-converting_phage	2.6e-92	100.0
WP_001299338.1\|2729682_2729898_-\|holin	class II holin family protein	A0A0P0ZC45	Stx2-converting_phage	5.9e-33	98.6
WP_001290231.1\|2729974_2730247_-	DUF826 domain-containing protein	A0A0P0ZBB8	Stx2-converting_phage	2.2e-21	100.0
WP_000143458.1\|2730287_2730467_-	DUF1378 family protein	A0A2R2Z345	Escherichia_phage	2.2e-25	100.0
WP_072617035.1\|2730603_2732541_-	SASA family carbohydrate esterase	A0A0N7KZH7	Stx2-converting_phage	0.0e+00	99.4
WP_001303568.1\|2732784_2733108_+	anti-adapter protein IraM	Q8HAJ1	Enterobacteria_phage	6.9e-62	100.0
WP_000738080.1\|2733404_2733674_-	Shiga toxin Stx2c subunit B	Q5TJL5	Enterobacteria_phage	2.1e-43	100.0
WP_000649751.1\|2733685_2734645_-	Shiga toxin Stx2c subunit A	Q5TJL6	Enterobacteria_phage	4.3e-176	100.0
WP_000512807.1\|2735294_2735783_-	late gene antiterminator protein	Q5TJL7	Enterobacteria_phage	7.0e-90	100.0
WP_001028858.1\|2735773_2736445_-	serine/threonine protein phosphatase	Q5TJL8	Enterobacteria_phage	2.4e-133	100.0
WP_001108004.1\|2736441_2737047_-	recombination protein NinG	Q5TJL9	Enterobacteria_phage	3.3e-97	100.0
WP_001004016.1\|2737046_2737769_-	phage antirepressor KilAC domain-containing protein	A0A0P0ZCB2	Stx2-converting_phage	6.0e-130	100.0
WP_001455113.1\|2737843_2738323_-	phage antirepressor Ant	Q8HA19	Enterobacteria_phage	3.1e-90	100.0
WP_162829202.1\|2738381_2739594_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	7.6e-170	100.0
WP_000208502.1\|2740092_2740851_-	ORF6N domain-containing protein	B6ETC2	Enterobacteria_phage	2.0e-115	100.0
WP_001254256.1\|2741125_2741308_-	NinE family protein	A0A0N7C1X3	Escherichia_phage	5.7e-29	100.0
WP_000153268.1\|2741304_2741832_-	phage N-6-adenine-methyltransferase	Q9EYC2	Enterobacteria_phage	1.6e-100	100.0
WP_001303571.1\|2741828_2742275_-	recombination protein NinB	Q8VNP6	Enterobacteria_phage	2.4e-81	100.0
WP_001449504.1\|2742231_2742468_-	restriction alleviation protein, Lar family	Q687G3	Enterobacteria_phage	9.3e-40	100.0
WP_000103678.1\|2742478_2742694_-	hypothetical protein	A0A0N7KZ98	Stx2-converting_phage	7.7e-33	100.0
WP_001000130.1\|2742826_2743105_-	hypothetical protein	Q9EYB9	Enterobacteria_phage	4.4e-49	100.0
WP_001248388.1\|2743175_2744552_-	AAA family ATPase	A0A0P0ZC27	Stx2-converting_phage	5.7e-254	100.0
WP_000539354.1\|2744548_2745370_-	replication protein	A0A0N7KZ97	Stx2-converting_phage	2.0e-153	100.0
WP_000166961.1\|2745356_2745518_-	hypothetical protein	Q76H53	Enterobacteria_phage	1.3e-21	100.0
WP_000442612.1\|2745550_2745847_-	hypothetical protein	A4KWW1	Enterobacteria_phage	4.0e-48	100.0
WP_000067727.1\|2745988_2746204_-	helix-turn-helix transcriptional regulator	A0A0N7C2U7	Escherichia_phage	2.2e-35	100.0
WP_001302016.1\|2746279_2746975_+	LexA family transcriptional regulator	A0A0N7BTS4	Escherichia_phage	8.6e-134	100.0
WP_001130059.1\|2747476_2747998_+	hypothetical protein	A0A0N7BTU4	Escherichia_phage	1.8e-88	100.0
WP_000438343.1\|2748566_2748749_+	hypothetical protein	A0A0N7C057	Escherichia_phage	2.8e-28	100.0
WP_000088203.1\|2748726_2748999_+	hypothetical protein	A0A0N7C217	Escherichia_phage	5.7e-41	100.0
WP_000394299.1\|2749057_2749309_+	hypothetical protein	A4KWV4	Enterobacteria_phage	5.6e-43	100.0
WP_000065362.1\|2749491_2749860_+	DUF2528 family protein	A0A0N7C1W2	Escherichia_phage	2.0e-65	100.0
WP_001198861.1\|2749932_2750097_+\|protease	protease FtsH-inhibitory lysogeny factor CIII	Q776Q5	Enterobacteria_phage	1.1e-26	100.0
WP_000372937.1\|2750065_2750209_+	host cell division inhibitory peptide Kil	A0A0N7C2U2	Escherichia_phage	1.2e-18	100.0
WP_000995487.1\|2750283_2750580_+	host-nuclease inhibitor protein Gam	A0A0P0ZE86	Stx2-converting_phage	3.3e-50	100.0
WP_000100845.1\|2750585_2751371_+	phage recombination protein Bet	A0A0N7KZJ3	Stx2-converting_phage	1.1e-148	100.0
WP_054428303.1\|2751367_2752048_+	YqaJ viral recombinase family protein	A0A0P0ZCQ7	Stx2-converting_phage	1.2e-132	100.0
WP_000682304.1\|2752044_2752227_+	DUF1317 domain-containing protein	A0A0P0ZD61	Stx2-converting_phage	7.4e-29	100.0
WP_000548531.1\|2752199_2752391_+	DUF1382 family protein	A0A0P0ZC67	Stx2-converting_phage	7.3e-27	100.0
WP_000188870.1\|2752467_2752683_+	hypothetical protein	A0A1I9LJM7	Stx_converting_phage	1.0e-32	100.0
WP_000763383.1\|2752781_2753003_+	TraR/DksA family transcriptional regulator	A0A1I9LJM6	Stx_converting_phage	2.9e-35	100.0
WP_001289954.1\|2752999_2753947_+	ead/Ea22-like family protein	A0A0P0ZE96	Stx2-converting_phage	3.6e-183	100.0
WP_000207904.1\|2754460_2754817_+	hypothetical protein	A0A0N7KZJ2	Stx2-converting_phage	1.2e-62	99.2
WP_000610373.1\|2754813_2755164_+	DUF551 domain-containing protein	A0A0N7KZ94	Stx2-converting_phage	7.8e-67	100.0
WP_001281188.1\|2755351_2755696_+	hypothetical protein	A0A0P0ZB93	Stx2-converting_phage	9.0e-60	100.0
WP_000132739.1\|2755777_2755969_+	AlpA family phage regulatory protein	A0A0P0ZBL0	Stx2-converting_phage	1.7e-31	100.0
WP_001007947.1\|2755949_2757128_-\|integrase	site-specific integrase	A0A0P0ZDN8	Stx2-converting_phage	1.8e-232	100.0
2764271:2764285	attR	NA	NA	NA	NA

DBSCAN-SWA_13

2840350 : 2878404

Escherichia_phage(59.52%)

tail,terminase,head,portal,holin,plate,tRNA,capsid,lysis,integrase

attL 2844650:2844677|attR 2876597:2876624

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000675144.1\|2840350_2841754_+	two-component system sensor histidine kinase BaeS	W8CYF6	Bacillus_phage	1.2e-33	29.4
WP_000137884.1\|2841750_2842473_+	two-component system response regulator BaeR	W8CYM9	Bacillus_phage	2.9e-31	33.6
WP_001301848.1\|2842663_2842996_+	YegP family protein	NA	NA	NA	NA
WP_000476015.1\|2843143_2844505_+\|tRNA	tRNA 5-hydroxyuridine modification protein YegQ	Q6DW11	Phage_TP	7.1e-217	99.5
2844650:2844677	attL	NA	NA	NA	NA
WP_000468308.1\|2844778_2844997_-	prophage transcriptional regulator OgrK	A0A0F7LDQ9	Escherichia_phage	4.7e-38	100.0
WP_000882933.1\|2845078_2846242_-	phage late control D family protein	U5N3V4	Enterobacteria_phage	1.7e-203	98.4
WP_000978913.1\|2846241_2846721_-\|tail	phage tail protein	Q7Y4C7	Escherichia_virus	3.3e-84	98.7
WP_000069957.1\|2846735_2849183_-\|tail	phage tail tape measure protein	M1T2S3	Escherichia_phage	0.0e+00	96.3
WP_001496926.1\|2849175_2849295_-\|tail	GpE family phage tail protein	A0A0F7LCR6	Escherichia_phage	1.4e-15	97.4
WP_001031303.1\|2849327_2849603_-\|tail	phage tail assembly protein	A0A0F7LDQ8	Escherichia_phage	5.7e-41	100.0
WP_001251408.1\|2849659_2850178_-\|tail	phage major tail tube protein	A0A0F7LDZ1	Escherichia_phage	1.4e-93	100.0
WP_001286704.1\|2850190_2851381_-\|tail	phage tail sheath protein	A0A0F7LBW9	Escherichia_phage	2.6e-223	99.0
WP_000905094.1\|2851440_2852034_-	recombinase family protein	A0A0F7LA37	Escherichia_phage	2.1e-104	97.5
WP_001008233.1\|2852488_2852932_+\|tail	tail fiber assembly protein	A0A0F7LDZ0	Escherichia_phage	4.9e-82	99.3
WP_001285352.1\|2854816_2855428_-\|tail	phage tail protein I	A0A0F7LA36	Escherichia_phage	3.8e-117	99.5
WP_001121479.1\|2855420_2856329_-\|plate	baseplate assembly protein	A0A0F7LCQ9	Escherichia_phage	7.5e-162	99.7
WP_000127154.1\|2856333_2856681_-	GPW/gp25 family protein	A0A0F7LDQ1	Escherichia_phage	6.5e-58	99.1
WP_001093728.1\|2856677_2857313_-\|plate	phage baseplate assembly protein V	U5N3F0	Enterobacteria_phage	2.9e-112	98.1
WP_001001809.1\|2857379_2857832_-	phage virion morphogenesis protein	A0A0F7LBV9	Escherichia_phage	2.0e-75	98.0
WP_000917144.1\|2857824_2858292_-\|tail	phage tail protein	A0A0F7LA33	Escherichia_phage	2.5e-81	98.7
WP_001300730.1\|2858254_2858428_-	hypothetical protein	Q7Y4E1	Escherichia_virus	5.2e-24	94.7
WP_000040644.1\|2858399_2858825_-\|lysis	LysB family phage lysis regulatory protein	A0A0F7LDJ6	Escherichia_phage	2.0e-64	94.3
WP_000736555.1\|2858812_2859238_-	hypothetical protein	A0A0F7LBP4	Escherichia_phage	1.2e-61	98.6
WP_001144101.1\|2859252_2859750_-	glycoside hydrolase family 104 protein	A0A0F7LBS0	Escherichia_phage	3.1e-93	100.0
WP_000123123.1\|2859749_2860031_-\|holin	phage holin family protein	A0A0F7LA12	Escherichia_phage	1.3e-43	100.0
WP_000846406.1\|2860034_2860238_-\|tail	tail protein X	A0A0F7LCN2	Escherichia_phage	5.2e-31	98.5
WP_000988633.1\|2860237_2860747_-\|head	head completion/stabilization protein	U5N0S3	Enterobacteria_phage	1.1e-90	100.0
WP_000203418.1\|2860846_2861590_-\|terminase	terminase endonuclease subunit	A0A0F7LBP7	Escherichia_phage	7.3e-123	97.6
WP_001248594.1\|2861593_2862667_-\|capsid	phage major capsid protein, P2 family	Q83VT1	Escherichia_phage	1.6e-200	99.2
WP_001085952.1\|2862725_2863580_-\|capsid	GPO family capsid scaffolding protein	Q778Z1	Enterobacteria_phage	8.6e-136	99.3
WP_000156848.1\|2863753_2865526_+\|terminase	terminase ATPase subunit family protein	A0A0F7LCM8	Escherichia_phage	0.0e+00	99.7
WP_000038161.1\|2865525_2866560_+\|portal	phage portal protein	A0A0F7LDI7	Escherichia_phage	1.9e-201	100.0
WP_000844437.1\|2866877_2868845_-	hypothetical protein	NA	NA	NA	NA
WP_001302413.1\|2868844_2869297_-	hypothetical protein	NA	NA	NA	NA
WP_000268574.1\|2870655_2872938_-	replication endonuclease	M1SV59	Escherichia_phage	0.0e+00	91.3
WP_000027664.1\|2872927_2873203_-	DUF5405 family protein	U5N3W1	Enterobacteria_phage	3.8e-45	100.0
WP_001113265.1\|2873199_2873424_-	TraR/DksA C4-type zinc finger protein	S4TRY6	Salmonella_phage	3.2e-34	98.6
WP_001277898.1\|2873426_2873726_-	DUF5405 family protein	S4TUD1	Salmonella_phage	3.2e-45	99.0
WP_000557698.1\|2873725_2873950_-	DUF2732 family protein	S4TP68	Salmonella_phage	5.2e-32	97.3
WP_000217673.1\|2874013_2874514_-	hypothetical protein	M1SV55	Escherichia_phage	1.7e-91	99.4
WP_001005162.1\|2874510_2874681_-	hypothetical protein	S4TNZ7	Salmonella_phage	6.1e-25	100.0
WP_001081582.1\|2874691_2874967_-	regulatory phage cox family protein	Q1JS60	Enterobacteria_phage	1.3e-48	100.0
WP_000020919.1\|2875088_2875388_+	helix-turn-helix domain-containing protein	Q1JS61	Enterobacteria_phage	2.4e-48	100.0
WP_000985260.1\|2875503_2876517_+\|integrase	site-specific integrase	Q83VS6	Escherichia_phage	8.3e-194	99.4
WP_001303579.1\|2876781_2877099_-	hypothetical protein	NA	NA	NA	NA
2876597:2876624	attR	NA	NA	NA	NA
WP_000807362.1\|2877504_2878404_+	lipid kinase YegS	A0A1V0SBJ0	Catovirus	1.3e-12	29.0

DBSCAN-SWA_14

2921646 : 2931092

Enterobacteria_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001302810.1\|2921646_2922783_+	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	1.9e-167	100.0
WP_001087225.1\|2922779_2924783_+	SWIM zinc finger family protein	Q9EYF6	Enterobacteria_phage	0.0e+00	100.0
WP_001295429.1\|2924907_2925369_+	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	1.9e-76	100.0
WP_001295430.1\|2925410_2925881_-	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.8e-82	100.0
WP_000598641.1\|2925927_2926647_-	two-component system response regulator BtsR	NA	NA	NA	NA
WP_001301761.1\|2926643_2928329_-	two-component regulatory system sensor histidine kinase BtsS	Q9EYF3	Enterobacteria_phage	1.7e-305	100.0
WP_001240409.1\|2928550_2929282_+	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	1.5e-112	100.0
WP_001216963.1\|2929341_2929449_+	protein YohO	NA	NA	NA	NA
WP_000783120.1\|2929429_2930161_-	glycine betaine ABC transporter permease YehW	NA	NA	NA	NA
WP_000569336.1\|2930165_2931092_-	glycine betaine ABC transporter ATP binding protein YehX	G3M9Y6	Bacillus_virus	4.8e-23	30.8

DBSCAN-SWA_15

3144773 : 3238821

105

Stx1_converting_phage(29.11%)

tail,portal,holin,transposase,tRNA,capsid,lysis,integrase,protease

attL 3165947:3165963|attR 3235810:3235826

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001283590.1\|3144773_3145586_-\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_001289184.1\|3145585_3146599_-	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_000699109.1\|3146664_3147801_-	4-phosphoerythronate dehydrogenase PdxB	A0A2R8FDS8	Brazilian_cedratvirus	3.1e-24	29.8
WP_000615801.1\|3147899_3148895_+	flagella biosynthesis regulator Flk	NA	NA	NA	NA
WP_000127753.1\|3148891_3150070_-	MFS transporter	NA	NA	NA	NA
WP_000817183.1\|3150344_3151565_-	beta-ketoacyl-ACP synthase I	NA	NA	NA	NA
WP_000683769.1\|3151723_3153730_+\|tRNA	bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	NA	NA	NA	NA
WP_000559764.1\|3153850_3154129_-	YfcL family protein	NA	NA	NA	NA
WP_001089225.1\|3154162_3154711_-	elongation factor P hydroxylase	NA	NA	NA	NA
WP_000447364.1\|3154710_3155520_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_001043834.1\|3155519_3156344_-	penicillin-insensitive murein endopeptidase	NA	NA	NA	NA
WP_001297933.1\|3156347_3157433_-	chorismate synthase	A0A291AU41	Pandoravirus	7.0e-90	47.8
WP_001302029.1\|3157467_3158400_-	50S ribosomal protein L3 N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_000730817.1\|3158565_3159117_+	endonuclease SmrB	NA	NA	NA	NA
WP_001301548.1\|3159287_3160130_-	DUF2544 domain-containing protein	NA	NA	NA	NA
WP_000794741.1\|3160131_3160653_-	fimbrial protein	NA	NA	NA	NA
WP_000822672.1\|3160649_3161120_-	fimbrial protein	NA	NA	NA	NA
WP_000675435.1\|3161116_3161617_-	fimbrial protein	NA	NA	NA	NA
WP_000182852.1\|3161627_3162386_-	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_001112844.1\|3162408_3165048_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_000033336.1\|3165129_3165693_-	type 1 fimbrial protein	NA	NA	NA	NA
3165947:3165963	attL	NA	NA	NA	NA
WP_001195817.1\|3166338_3166824_-	phosphohistidine phosphatase SixA	NA	NA	NA	NA
WP_000426146.1\|3167026_3169171_-	fatty acid oxidation complex subunit alpha FadJ	NA	NA	NA	NA
WP_000531969.1\|3169170_3170481_-	acetyl-CoA C-acyltransferase FadI	NA	NA	NA	NA
WP_000030901.1\|3170660_3170945_-	YfcZ/YiiS family protein	NA	NA	NA	NA
WP_001301981.1\|3171316_3172657_+	long-chain fatty acid transporter FadL	NA	NA	NA	NA
WP_000952959.1\|3173021_3174053_+	hypothetical protein	NA	NA	NA	NA
WP_000776768.1\|3174447_3175203_-	phospholipid-binding lipoprotein MlaA	NA	NA	NA	NA
WP_000368131.1\|3175496_3176429_+	formate/nitrite transporter family protein	E7DYY8	Enterobacteria_phage	1.2e-167	100.0
WP_072617036.1\|3176650_3185035_-	hypothetical protein	A0A1U9AJC4	Stx1_converting_phage	0.0e+00	100.0
WP_000012455.1\|3185104_3186370_-	hypothetical protein	A0A1U9AJC6	Stx1_converting_phage	2.4e-206	100.0
WP_000540394.1\|3186380_3186632_-	hypothetical protein	A0A2R2Z351	Escherichia_phage	7.9e-13	100.0
WP_000455649.1\|3186641_3187088_-	hypothetical protein	A0A2R2Z357	Escherichia_phage	6.2e-77	100.0
WP_000509481.1\|3187090_3187747_-	hypothetical protein	A0A2R2Z361	Escherichia_phage	2.4e-109	100.0
WP_000035558.1\|3187840_3188242_-	hypothetical protein	A0A2R2Z359	Escherichia_phage	3.7e-73	100.0
WP_000078907.1\|3188298_3188439_-	Hok/Gef family protein	A0A2R2X2B4	Escherichia_phage	3.1e-19	100.0
WP_000835358.1\|3188671_3189406_-	Ail/Lom family outer membrane beta-barrel protein	A0A1U9AJC8	Stx1_converting_phage	1.3e-135	100.0
WP_001426808.1\|3189496_3190114_-	hypothetical protein	A0A1U9AJB9	Stx1_converting_phage	8.8e-122	100.0
WP_072617037.1\|3190119_3190392_-	hypothetical protein	A0A2R2Z367	Escherichia_phage	1.2e-46	100.0
WP_001171554.1\|3190472_3190853_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	1.4e-66	100.0
WP_000612591.1\|3190849_3191197_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_000998048.1\|3191246_3192785_+\|transposase	IS66-like element ISEc8 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.5e-300	100.0
WP_000197192.1\|3192862_3194131_-	host specificity protein J	A0A2R2Z364	Escherichia_phage	4.9e-220	100.0
WP_001146325.1\|3194127_3195753_-	hypothetical protein	A0A1U9AJB6	Stx1_converting_phage	0.0e+00	100.0
WP_001426815.1\|3196047_3196236_-	hypothetical protein	A0A1U9AJB8	Stx1_converting_phage	9.0e-30	100.0
WP_001023473.1\|3196377_3196647_-\|tail	phage tail fiber C-terminal domain-containing protein	A0A1U9AJC2	Stx1_converting_phage	8.4e-45	100.0
WP_064234923.1\|3196648_3198544_-\|tail	phage tail fiber C-terminal domain-containing protein	A0A1I9LJS9	Stx_converting_phage	1.0e-64	100.0
WP_000207923.1\|3198540_3199191_-	hypothetical protein	A0A2R2X2B3	Escherichia_phage	7.8e-121	100.0
WP_000829200.1\|3199190_3199754_-	hypothetical protein	A0A2R2Z349	Escherichia_phage	3.2e-102	100.0
WP_001367376.1\|3199737_3200199_-	hypothetical protein	A0A0P0ZG73	Escherichia_phage	6.0e-75	100.0
WP_001140442.1\|3200248_3200638_-	hypothetical protein	A0A2R2Z353	Escherichia_phage	9.9e-63	100.0
WP_000214474.1\|3200693_3201908_-\|capsid	N4-gp56 family major capsid protein	A0A2R2Z358	Escherichia_phage	1.3e-233	100.0
WP_000345010.1\|3201931_3202939_-	hypothetical protein	A0A2R2Z355	Escherichia_phage	2.3e-180	100.0
WP_000787520.1\|3203096_3205241_-\|portal	portal protein	A0A1U9AJF2	Stx1_converting_phage	0.0e+00	100.0
WP_000143991.1\|3205240_3206947_-	hypothetical protein	A0A1U9AJA6	Stx1_converting_phage	0.0e+00	100.0
WP_001086076.1\|3206927_3207734_-	hypothetical protein	A0A1U9AJA9	Stx1_converting_phage	1.7e-133	100.0
WP_001301714.1\|3207789_3207993_-	hypothetical protein	A0A2R2Z338	Escherichia_phage	7.7e-35	100.0
WP_000738505.1\|3208142_3208436_+	serum resistance lipoprotein Bor	A0A2R2X2B2	Escherichia_phage	6.8e-48	100.0
WP_001082653.1\|3208467_3208932_-\|lysis	lysis protein	A0A1U9AJA1	Stx1_converting_phage	4.5e-78	100.0
WP_000455406.1\|3208939_3209089_-	hypothetical protein	A0A0P0ZFU6	Escherichia_phage	2.4e-17	100.0
WP_001369534.1\|3209088_3209631_-	hypothetical protein	A0A1U9AJ99	Stx1_converting_phage	4.8e-100	100.0
WP_001080433.1\|3209945_3210479_-	lysozyme	A0A1U9AJ98	Stx1_converting_phage	4.6e-103	100.0
WP_000284510.1\|3210483_3210699_-\|holin	class II holin family protein	G9L6J5	Escherichia_phage	9.0e-34	100.0
WP_001290231.1\|3210775_3211048_-	DUF826 domain-containing protein	A0A0P0ZBB8	Stx2-converting_phage	2.2e-21	100.0
WP_000143458.1\|3211088_3211268_-	DUF1378 family protein	A0A2R2Z345	Escherichia_phage	2.2e-25	100.0
WP_064032101.1\|3211404_3213345_-	SASA family carbohydrate esterase	A0A1U9AJ89	Stx1_converting_phage	0.0e+00	100.0
WP_000752026.1\|3213848_3214118_-	Shiga toxin Stx1a subunit B	Q7AYI7	Enterobacteria_phage	1.6e-43	100.0
WP_000691354.1\|3214127_3215075_-	Shiga toxin Stx1 subunit A	Q777W4	Enterobacteria_phage	3.2e-171	100.0
WP_001204849.1\|3215581_3216016_-	antitermination protein	Q8VNP1	Enterobacteria_phage	4.3e-83	100.0
WP_000144764.1\|3216008_3216203_-	phage NinH family protein	G9L694	Escherichia_phage	1.9e-30	100.0
WP_064032103.1\|3216199_3216811_-	recombination protein NinG	A0A1U9AJF8	Stx1_converting_phage	1.1e-97	100.0
WP_001108081.1\|3216785_3217352_-	HNH endonuclease	A0A1U9AJK5	Stx1_converting_phage	2.3e-108	100.0
WP_001502725.1\|3217933_3219706_+	hypothetical protein	A0A1U9AJG3	Stx1_converting_phage	0.0e+00	100.0
WP_001254221.1\|3220209_3220392_-	NinE family protein	Q8H9Z6	Enterobacteria_phage	1.3e-28	98.3
WP_000153270.1\|3220388_3220916_-	phage N-6-adenine-methyltransferase	K7PJZ4	Enterobacterial_phage	9.5e-101	100.0
WP_001310475.1\|3220912_3221359_-	recombination protein NinB	A0A1U9AJ79	Stx1_converting_phage	2.4e-81	100.0
WP_001281772.1\|3221315_3221552_-	restriction alleviation protein, Lar family	Q8HA09	Enterobacteria_phage	1.2e-39	100.0
WP_000103679.1\|3221562_3221778_-	hypothetical protein	A0A1I9LJP7	Stx_converting_phage	1.3e-32	100.0
WP_001000127.1\|3221910_3222189_-	hypothetical protein	Q9ZWY1	Enterobacteria_phage	3.4e-49	100.0
WP_000145931.1\|3222259_3222550_-	protein ren	A0A1I9LJP5	Stx_converting_phage	9.6e-47	100.0
WP_000788928.1\|3222546_3223248_-	Replication protein P	C1JJ58	Enterobacteria_phage	3.4e-130	100.0
WP_000185454.1\|3223244_3224183_-	replication protein	A0A1I9LJP3	Stx_converting_phage	1.3e-172	100.0
WP_000438532.1\|3224215_3224512_-	hypothetical protein	A0A1U9AJB5	Stx1_converting_phage	3.1e-48	100.0
WP_000064148.1\|3224650_3224884_-	hypothetical protein	A0A0P0ZDD7	Stx2-converting_phage	8.0e-36	100.0
WP_000428098.1\|3224997_3225702_+	helix-turn-helix transcriptional regulator	A0A0P0ZE37	Stx2-converting_phage	1.1e-133	100.0
WP_000198444.1\|3226591_3226975_+	hypothetical protein	G9L671	Escherichia_phage	3.9e-64	100.0
WP_001502698.1\|3227033_3227504_+	hypothetical protein	A0A1U9AJ69	Stx1_converting_phage	1.7e-88	100.0
WP_072617038.1\|3227654_3228023_+	DUF2528 family protein	A0A1U9AJB3	Stx1_converting_phage	2.0e-65	100.0
WP_001198861.1\|3228095_3228260_+\|protease	protease FtsH-inhibitory lysogeny factor CIII	Q776Q5	Enterobacteria_phage	1.1e-26	100.0
WP_000372941.1\|3228228_3228372_+	host cell division inhibitory peptide Kil	A0A1I9LJN2	Stx_converting_phage	1.2e-18	100.0
WP_000995439.1\|3228447_3228744_+	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	1.6e-49	100.0
WP_000100845.1\|3228749_3229535_+	phage recombination protein Bet	A0A0N7KZJ3	Stx2-converting_phage	1.1e-148	100.0
WP_054428303.1\|3229531_3230212_+	YqaJ viral recombinase family protein	A0A0P0ZCQ7	Stx2-converting_phage	1.2e-132	100.0
WP_000682304.1\|3230208_3230391_+	DUF1317 domain-containing protein	A0A0P0ZD61	Stx2-converting_phage	7.4e-29	100.0
WP_000548531.1\|3230363_3230555_+	DUF1382 family protein	A0A0P0ZC67	Stx2-converting_phage	7.3e-27	100.0
WP_000188870.1\|3230631_3230847_+	hypothetical protein	A0A1I9LJM7	Stx_converting_phage	1.0e-32	100.0
WP_000763383.1\|3230945_3231167_+	TraR/DksA family transcriptional regulator	A0A1I9LJM6	Stx_converting_phage	2.9e-35	100.0
WP_000497812.1\|3232560_3232812_+	DUF4222 domain-containing protein	G3CFG8	Escherichia_phage	2.9e-39	100.0
WP_000405131.1\|3232872_3233055_+	helix-turn-helix domain-containing protein	A0A1U9AJ41	Stx1_converting_phage	4.1e-27	100.0
WP_001218301.1\|3233038_3234208_-\|integrase	site-specific integrase	A0A1U9AJ52	Stx1_converting_phage	5.7e-231	100.0
WP_000958700.1\|3234639_3235797_+\|integrase	prophage integrase IntS	E7DYQ6	Enterobacteria_phage	2.2e-222	100.0
WP_000257010.1\|3235971_3237108_-	phage DNA ejection protein	Q716G3	Shigella_phage	1.4e-80	72.8
3235810:3235826	attR	NA	NA	NA	NA
WP_000960724.1\|3237117_3237798_-	DNA transfer protein	G5DA80	Enterobacteria_phage	1.8e-59	71.0
WP_000403517.1\|3237784_3238252_-	DUF2824 family protein	Q2A0B3	Sodalis_phage	1.7e-64	74.7
WP_000950857.1\|3238251_3238821_-	hypothetical protein	Q716G6	Shigella_phage	4.6e-69	99.3

DBSCAN-SWA_16

3516194 : 3530945

Enterobacteria_phage(42.86%)

holin,tail,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000162574.1\|3516194_3516677_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	4.0e-29	46.8
WP_001217542.1\|3517522_3517771_+	DinI-like family protein	A5LH55	Enterobacteria_phage	3.1e-38	98.8
WP_001132157.1\|3518272_3518863_-	T3SS effector guanine nucleotide exchange factor EspM2	NA	NA	NA	NA
WP_001144077.1\|3519045_3519696_+	T3SS effector NleG family protein	B6DZZ5	Stx2-converting_phage	2.8e-25	37.2
WP_001301665.1\|3519774_3520833_+	T3SS effector EspW	NA	NA	NA	NA
WP_000442132.1\|3520962_3521385_-	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	5.7e-72	97.0
WP_001023396.1\|3521545_3521815_-\|tail	phage tail fiber C-terminal domain-containing protein	B6DZB8	Enterobacteria_phage	3.8e-45	100.0
WP_162829202.1\|3522032_3523245_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	7.6e-170	100.0
WP_000612591.1\|3523746_3524094_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_001171554.1\|3524090_3524471_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	1.4e-66	100.0
WP_000731259.1\|3524827_3525172_-	YdfR family protein	B6DZ91	Enterobacteria_phage	4.5e-59	100.0
WP_000284517.1\|3525176_3525392_-\|holin	class II holin family protein	A0A0P0ZC45	Stx2-converting_phage	4.5e-33	98.6
WP_000143068.1\|3525541_3527395_-	DUF1737 domain-containing protein	H6WZJ9	Escherichia_phage	0.0e+00	97.7
WP_000499458.1\|3527802_3527970_-	DUF3927 family protein	NA	NA	NA	NA
WP_001302581.1\|3528055_3528799_-	hypothetical protein	NA	NA	NA	NA
WP_001235472.1\|3529051_3529675_-	antitermination protein	K7PM87	Enterobacteria_phage	2.2e-112	98.1
WP_001028854.1\|3529671_3530337_-	serine/threonine protein phosphatase	Q5TJL8	Enterobacteria_phage	5.0e-131	99.5
WP_001223948.1\|3530333_3530945_-	recombination protein NinG	A0A1U9AJF8	Stx1_converting_phage	2.5e-92	95.6

DBSCAN-SWA_17

3864200 : 3915705

Stx2-converting_phage(33.33%)

tRNA,transposase,integrase,protease

attL 3877146:3877180|attR 3922968:3923002

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000701842.1\|3864200_3864959_+\|protease	metalloprotease LoiP	NA	NA	NA	NA
WP_000105566.1\|3865164_3866085_-	agmatinase	NA	NA	NA	NA
WP_000758914.1\|3866220_3866952_-	lipoprotein	NA	NA	NA	NA
WP_001295380.1\|3867097_3869074_-	biosynthetic arginine decarboxylase	NA	NA	NA	NA
WP_001297406.1\|3869082_3869214_-	acid stress response protein YqgB	NA	NA	NA	NA
WP_001303650.1\|3869349_3869565_+	hypothetical protein	NA	NA	NA	NA
WP_001062128.1\|3869868_3871023_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	4.0e-128	63.2
WP_001112296.1\|3871459_3872854_+	galactose/proton symporter	NA	NA	NA	NA
WP_001303653.1\|3872930_3873428_+\|protease	SprT family zinc-dependent metalloprotease	NA	NA	NA	NA
WP_000286494.1\|3873522_3874230_+	deoxyribonuclease I	NA	NA	NA	NA
WP_001222509.1\|3874309_3875041_+	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_000593272.1\|3875053_3876001_+	glutathione synthase	NA	NA	NA	NA
WP_001053178.1\|3876112_3876676_+	YqgE/AlgH family protein	NA	NA	NA	NA
WP_000017110.1\|3876675_3877092_+	Holliday junction resolvase RuvX	NA	NA	NA	NA
3877146:3877180	attL	NA	NA	NA	NA
WP_001055622.1\|3877282_3878263_-	type IV pilus twitching motility protein PilT	NA	NA	NA	NA
WP_000997795.1\|3878280_3878985_+	pyridoxal phosphate homeostasis protein	NA	NA	NA	NA
WP_001094831.1\|3879002_3879569_+	osmotic shock tolerance protein YggT	NA	NA	NA	NA
WP_001277224.1\|3879565_3879856_+	YggU family protein	NA	NA	NA	NA
WP_001174762.1\|3879863_3880457_+	XTP/dITP diphosphatase	NA	NA	NA	NA
WP_000239959.1\|3880449_3881586_+	radical SAM family heme chaperone HemW	NA	NA	NA	NA
WP_000745247.1\|3881828_3882836_-	DUF1202 family protein	NA	NA	NA	NA
WP_000394102.1\|3882952_3883999_-	L-asparaginase 2	NA	NA	NA	NA
WP_000984796.1\|3884174_3884894_-	DUF2884 domain-containing protein	NA	NA	NA	NA
WP_001107568.1\|3885077_3885404_-	YggL family protein	NA	NA	NA	NA
WP_000786908.1\|3885403_3886123_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_001301529.1\|3886283_3887336_+	A/G-specific adenine glycosylase	NA	NA	NA	NA
WP_000091700.1\|3887363_3887639_+	oxidative damage protection protein	NA	NA	NA	NA
WP_001302020.1\|3887703_3888783_+	membrane-bound lytic murein transglycosylase MltC	NA	NA	NA	NA
WP_001049791.1\|3888984_3890241_+	nucleoside permease NupG	NA	NA	NA	NA
WP_000839815.1\|3890290_3892426_-	ornithine decarboxylase	NA	NA	NA	NA
WP_000234483.1\|3892823_3893531_+	DUF554 domain-containing protein	NA	NA	NA	NA
WP_001218882.1\|3893909_3895175_+\|integrase	integrase arm-type DNA-binding domain-containing protein	Q7M297	Enterobacteria_phage	3.0e-76	38.1
WP_001301939.1\|3896165_3896840_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	4.7e-12	31.6
WP_162829202.1\|3897097_3898310_+\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	7.6e-170	100.0
WP_000605048.1\|3900818_3901367_-	Ail/Lom family protein	Q9LA63	Enterobacterial_phage	9.8e-16	32.4
WP_001453071.1\|3901939_3902113_-	hypothetical protein	NA	NA	NA	NA
WP_001121626.1\|3904346_3905996_+	type III secretion system effector EspL2	NA	NA	NA	NA
WP_000953022.1\|3906603_3907593_+	type III secretion system effector arginine glycosyltransferase NleB	Q8HAB2	Salmonella_phage	2.9e-98	58.5
WP_000609742.1\|3907641_3908316_+	type III secretion system effector cysteine methyltransferase NleE	NA	NA	NA	NA
WP_001239097.1\|3910190_3912326_+	hydrogenase	NA	NA	NA	NA
WP_162829202.1\|3912365_3913579_-\|transposase	IS3 family transposase	A0A0N7C1X7	Escherichia_phage	7.6e-170	100.0
WP_000612591.1\|3913769_3914117_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
WP_000998048.1\|3914166_3915705_+\|transposase	IS66-like element ISEc8 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.5e-300	100.0
3922968:3923002	attR	NA	NA	NA	NA

DBSCAN-SWA_18

5119348 : 5134013

Enterobacteria_phage(43.75%)

tRNA,tail,integrase

attL 5120629:5120644|attR 5138158:5138173

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000956557.1\|5119348_5119882_+	hypothetical protein	K7PKJ4	Enterobacteria_phage	1.1e-99	100.0
WP_000654815.1\|5120078_5120252_+	hypothetical protein	K7PJQ2	Enterobacteria_phage	4.4e-23	100.0
WP_001093918.1\|5120299_5120581_-	pyocin activator PrtN family protein	K7PGU0	Enterobacteria_phage	8.7e-45	98.9
5120629:5120644	attL	NA	NA	NA	NA
WP_000829415.1\|5120925_5121123_-	hypothetical protein	K7PH57	Enterobacteria_phage	7.5e-11	68.6
WP_000145668.1\|5121458_5121743_-	hypothetical protein	I6S1S6	Salmonella_phage	1.3e-40	83.9
WP_001242740.1\|5121739_5122090_-	hypothetical protein	A0A0P0ZBF8	Stx2-converting_phage	1.6e-56	94.8
WP_000008211.1\|5122080_5122617_-	5'-deoxynucleotidase	U5P0T3	Shigella_phage	3.1e-99	98.3
WP_001230514.1\|5123938_5124538_+	Ail/Lom family outer membrane beta-barrel protein	A0A0P0ZE39	Stx2-converting_phage	5.7e-110	99.0
WP_000268945.1\|5124602_5125916_+\|tail	phage tail protein	A0A0P0ZE15	Stx2-converting_phage	2.5e-81	98.2
WP_001023355.1\|5125917_5126187_+\|tail	phage tail fiber C-terminal domain-containing protein	A0A0P0ZEF0	Stx2-converting_phage	2.7e-43	96.6
WP_001118000.1\|5126298_5126871_+	DUF1076 domain-containing protein	H6WZN1	Escherichia_phage	2.5e-46	53.2
WP_072140863.1\|5126943_5127573_+	DUF1076 domain-containing protein	B6DZB9	Enterobacteria_phage	1.4e-79	93.5
WP_001143816.1\|5127654_5128296_+	DUF1076 domain-containing protein	B6DZC0	Enterobacteria_phage	1.1e-106	99.1
WP_001217541.1\|5128456_5128705_-	DinI-like family protein	A5LH55	Enterobacteria_phage	3.1e-38	98.8
WP_000332269.1\|5128766_5129864_-\|integrase	site-specific integrase	S5MDN5	Escherichia_phage	2.1e-211	99.5
WP_000543819.1\|5129952_5130990_+\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA
WP_000891404.1\|5131123_5131366_+	envelope stress response protein PspG	NA	NA	NA	NA
WP_000918366.1\|5132597_5134013_+	replicative DNA helicase	O80281	Escherichia_phage	8.3e-200	78.1
5138158:5138173	attR	NA	NA	NA	NA

DBSCAN-SWA_19

5270884 : 5329929

Pectobacterium_phage(11.11%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000312488.1\|5270884_5272144_+\|protease	FtsH protease activity modulator HflK	A0A1L2CVV0	Pectobacterium_phage	3.6e-05	25.5
WP_001232412.1\|5272146_5273151_+\|protease	protease modulator HflC	NA	NA	NA	NA
WP_001089295.1\|5273232_5273430_+	DUF2065 domain-containing protein	NA	NA	NA	NA
WP_000527955.1\|5273533_5274832_+	adenylosuccinate synthase	W5S5V7	Pithovirus	2.2e-66	35.9
WP_001177639.1\|5275036_5275462_+	nitric oxide-sensing transcriptional repressor NsrR	NA	NA	NA	NA
WP_000076303.1\|5275500_5277942_+	ribonuclease R	Q0GXV6	Lactococcus_phage	2.4e-66	32.9
WP_001293282.1\|5278122_5278854_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_000220128.1\|5278980_5279382_+	DUF2170 family protein	NA	NA	NA	NA
WP_000511966.1\|5279400_5280099_+	PspA/IM30 family protein	NA	NA	NA	NA
WP_000012572.1\|5280149_5280809_+	YjfK family protein	NA	NA	NA	NA
WP_000547760.1\|5280826_5281225_+	DUF350 domain-containing protein	NA	NA	NA	NA
WP_000101670.1\|5281234_5281873_+	DUF1190 domain-containing protein	NA	NA	NA	NA
WP_000943960.1\|5281875_5283039_+	glutathionylspermidine synthase family protein	B2ZXR7	Ralstonia_phage	8.3e-81	43.8
WP_001301849.1\|5283122_5284748_+	isovaleryl-CoA dehydrogenase	NA	NA	NA	NA
WP_000811566.1\|5284864_5285140_-\|protease	protease activator YjfN	NA	NA	NA	NA
WP_000254636.1\|5285288_5285618_-	biofilm peroxide resistance protein BsmA	NA	NA	NA	NA
WP_000569696.1\|5285799_5286549_+	esterase	NA	NA	NA	NA
WP_000133631.1\|5286545_5287301_-	HTH-type transcriptional regulator UlaR	NA	NA	NA	NA
WP_001301921.1\|5288827_5290225_+	PTS ascorbate transporter subunit IIC	NA	NA	NA	NA
WP_000218362.1\|5290240_5290546_+	PTS ascorbate transporter subunit IIB	NA	NA	NA	NA
WP_000776517.1\|5290555_5291020_+	PTS ascorbate transporter subunit IIA	NA	NA	NA	NA
WP_000056760.1\|5291033_5291684_+	3-keto-L-gulonate-6-phosphate decarboxylase UlaD	NA	NA	NA	NA
WP_000949511.1\|5291693_5292548_+	L-ribulose-5-phosphate 3-epimerase UlaE	NA	NA	NA	NA
WP_001170812.1\|5292547_5293234_+	L-ribulose-5-phosphate 4-epimerase UlaF	NA	NA	NA	NA
WP_000492914.1\|5293362_5293638_-	DUF1471 domain-containing protein	NA	NA	NA	NA
WP_001216676.1\|5293964_5294360_+	30S ribosomal protein S6	NA	NA	NA	NA
WP_001296681.1\|5294366_5294681_+	primosomal replication protein N	NA	NA	NA	NA
WP_000135199.1\|5294685_5294913_+	30S ribosomal protein S18	NA	NA	NA	NA
WP_001196062.1\|5294954_5295404_+	50S ribosomal protein L9	NA	NA	NA	NA
WP_001301745.1\|5295474_5296269_-	DUF2686 family protein	NA	NA	NA	NA
WP_000604943.1\|5296891_5297323_-\|transposase	IS200/IS605-like element IS609 family transposase	A0A1S5RHE3	Helicobacter_phage	5.7e-43	59.9
WP_000826431.1\|5297330_5298539_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SL42	Escherichia_phage	5.4e-208	93.0
WP_001119481.1\|5298673_5299312_-	cell division protein YtfB	NA	NA	NA	NA
WP_000211225.1\|5299529_5300150_+	FKBP-type peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_000228346.1\|5300458_5301871_+	D-serine/D-alanine/glycine transporter	NA	NA	NA	NA
WP_000331454.1\|5301915_5302578_-	iron-sulfur cluster repair protein YtfE	NA	NA	NA	NA
WP_001301505.1\|5302685_5303651_-	DMT family transporter	NA	NA	NA	NA
WP_000560631.1\|5303758_5304619_-	NAD(P)H:quinone oxidoreductase	NA	NA	NA	NA
WP_000084622.1\|5304707_5305088_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000589487.1\|5305205_5307149_-	2',3'-cyclic-nucleotide 2'-phosphodiesterase	NA	NA	NA	NA
WP_000886884.1\|5307338_5308079_+	3'(2'),5'-bisphosphate nucleotidase CysQ	NA	NA	NA	NA
WP_000937658.1\|5308290_5309229_+	hypothetical protein	NA	NA	NA	NA
WP_000175287.1\|5309291_5309846_-	YtfJ family protein	NA	NA	NA	NA
WP_000689228.1\|5310170_5310377_+	DUF1107 domain-containing protein	NA	NA	NA	NA
WP_000935036.1\|5310489_5311833_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_001301936.1\|5312155_5312794_-	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_001269327.1\|5312999_5314733_+	autotransporter assembly complex protein TamA	NA	NA	NA	NA
WP_000060930.1\|5314729_5318509_+	autotransporter assembly complex protein TamB	NA	NA	NA	NA
WP_001219160.1\|5318511_5318853_+	gamma-glutamylcyclotransferase	NA	NA	NA	NA
WP_001223210.1\|5319064_5319316_+	type II toxin-antitoxin system antitoxin ChpS	NA	NA	NA	NA
WP_000239579.1\|5319309_5319660_+	endoribonuclease toxin ChpB	NA	NA	NA	NA
WP_000055075.1\|5319739_5320270_-	inorganic diphosphatase	A0A2H4J8U1	uncultured_Caudovirales_phage	1.2e-55	63.3
WP_000265942.1\|5320579_5321536_+	galactofuranose ABC transporter substrate-binding protein YtfQ	NA	NA	NA	NA
WP_000205805.1\|5321675_5323178_+	sugar ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	1.8e-11	30.3
WP_001301928.1\|5323191_5324214_+	ABC transporter permease	NA	NA	NA	NA
WP_000596020.1\|5324200_5325196_+	sugar ABC transporter permease YjfF	NA	NA	NA	NA
WP_000853749.1\|5325228_5326227_-	class 1 fructose-bisphosphatase	A0A1V0SKX4	Klosneuvirus	2.1e-69	42.6
WP_001219792.1\|5326402_5327776_+	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase	NA	NA	NA	NA
WP_000166270.1\|5327931_5328483_-	ribosome-associated protein	NA	NA	NA	NA
WP_001162171.1\|5328576_5329929_+\|protease	metalloprotease PmbA	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP018245

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection