CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP015423	Paenibacillus polymyxa strain J chromosome, complete genome	3 crisprs	cas3,csa3,WYL,DinG,DEDDh	2	9	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP015423_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015423_1

5113794-5114852

Orphan

NA:I-C

Consensus_repeat	Method
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	PILER-CR
GTCGCACTCTNTATGGAGTGCGTGGATTGAAA	CRT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CRISPRCasFinder

15 spacers

The CRISPR arrays of NZ_CP015423_1

>merge|NZ_CP015423|1|5113794-5114852|PILER-CR,CRT,CRISPRCasFinder
GTCGCACTCTGTATGGAGTGCGTGGATTGAAATTATCGAGAAAGGAGGACAAGGAAGATGCTAGAAAGGGTCGCACTCTGTATGGAGTGCGTGGATTGAAATCTCGGTGCTGACGCGTCCATAACCAGCAGCACGGTCGCACTCTGTATGGAGTGCGTGGATTGAAATGCTCAGGCTCGAAATGGACGGTTCAGGCGTCCCGCAGGTCGCACTCTGTATGGAGTGCGTGGATTGAAATGTCCATAGACCTAGCACCTACAGCAAAAATTCCTGTCGTCGCACTCTATATGAGTGCGTGGATTGAAATGCTTCGGAATCGGTCAAACGCCAGTGTGGGCCAAGCCGTCGCACTCTATATGAGTGCGTGGATTGAAATTCATTAACCACGGTCGATTGATCGTAACACCTAAACGTCGCACTCTATATGAGTGCGTGGATTGAAATTCTCCATGCAACGGCCTGATAGTGACGTGCTGGAGTCGCACTCTATATGAGTGCGTGGATTGAAATGATCTGGTTGTCCTCGACATCCGCGGTGGATATAGAGTCGCACTCTATATGAGTGCGTGGATTGAAATCATTCTTAATTGTGTTAACTCTAAAAACGTCTCCGTCGCACTCTATATGAGTGCGTGGATTGAAATTAAGTATGGATGGCGAAATCTAAACGGGACGAGTAGGGGTCGCACTCTGTATGGAGTGCGTGGATTGAAATTGCATTAGATGAGTGATCACGTTCGGCCTTACTATAGTCGCACTCTGTATGGAGTGCGTGGATTGAAATAGACGTAAGCCACCAAGCAAAGAAACAATTCTCCCAGGGTCGCACTCTGTATGGAGTGTGTGGATTGAAATTATTACGTTCGTGAGTTTGGTGATTCTGTCGCTCTGGTCGCACTCTGTATGGGGTGCGTGGATTGAAATGACACAAGAATTCGACAGACAGGAAGGAATTTCCGTCGCACTCTGTATGGAGTGCGTGGATTGAAATTCGAACATGAACACGCGTGGTATCTCCCCGTCGACGTCGCACTCTGTATAGAGTGAGTGGATTGAAAT

>NZ_CP015423|1|1|5113794-5114852|PILER-CR
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TATCGAGAAAGGAGGACAAGGAAGATGCTAGAAAGG
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CTCGGTGCTGACGCGTCCATAACCAGCAGCACG
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	GCTCAGGCTCGAAATGGACGGTTCAGGCGTCCCGCAG
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	GTCCATAGACCTAGCACCTACAGCAAAAATTCCTGTC
GTCGCACTCTATATGAGTGCGTGGATTGAAATG	CTTCGGAATCGGTCAAACGCCAGTGTGGGCCAAGCCG
TCGCACTCTATATGAGTGCGTGGATTGAAATTC	ATTAACCACGGTCGATTGATCGTAACACCTAAACGT
CGCACTCTATATGAGTGCGTGGATTGAAATTCT	CCATGCAACGGCCTGATAGTGACGTGCTGGAGTC
GCACTCTATATGAGTGCGTGGATTGAAATGATC	TGGTTGTCCTCGACATCCGCGGTGGATATAGAGTCG
CACTCTATATGAGTGCGTGGATTGAAATCATTC	TTAATTGTGTTAACTCTAAAAACGTCTCCGTCGC
ACTCTATATGAGTGCGTGGATTGAAATTAAGTA	TGGATGGCGAAATCTAAACGGGACGAGTAGGGGTCGCA
CTCTGTATGGAGTGCGTGGATTGAAATTGCATT	AGATGAGTGATCACGTTCGGCCTTACTATAGTCGCA
CTCTGTATGGAGTGCGTGGATTGAAATAGACGT	AAGCCACCAAGCAAAGAAACAATTCTCCCAGGGTCGCA
CTCTGTATGGAGTGTGTGGATTGAAATTATTAC	GTTCGTGAGTTTGGTGATTCTGTCGCTCTGGTCGCA
CTCTGTATGGGGTGCGTGGATTGAAATGACACA	AGAATTCGACAGACAGGAAGGAATTTCCGTCGCA
CTCTGTATGGAGTGCGTGGATTGAAATTCGAAC	ATGAACACGCGTGGTATCTCCCCGTCGACGTCGCA
CTCTGTATAGAGTGAGTGGATTGAAAT

>NZ_CP015423|1|1|5113795-5114850|CRT
TCGCACTCTGTATGGAGTGCGTGGATTGAAA	TTATCGAGAAAGGAGGACAAGGAAGATGCTAGAAAGGG
TCGCACTCTGTATGGAGTGCGTGGATTGAAA	TCTCGGTGCTGACGCGTCCATAACCAGCAGCACGG
TCGCACTCTGTATGGAGTGCGTGGATTGAAA	TGCTCAGGCTCGAAATGGACGGTTCAGGCGTCCCGCAGG
TCGCACTCTGTATGGAGTGCGTGGATTGAAA	TGTCCATAGACCTAGCACCTACAGCAAAAATTCCTGTC
GTCGCACTCTATATGAGTGCGTGGATTGAAA	TGCTTCGGAATCGGTCAAACGCCAGTGTGGGCCAAGCC
GTCGCACTCTATATGAGTGCGTGGATTGAAA	TTCATTAACCACGGTCGATTGATCGTAACACCTAAAC
GTCGCACTCTATATGAGTGCGTGGATTGAAA	TTCTCCATGCAACGGCCTGATAGTGACGTGCTGGA
GTCGCACTCTATATGAGTGCGTGGATTGAAA	TGATCTGGTTGTCCTCGACATCCGCGGTGGATATAGA
GTCGCACTCTATATGAGTGCGTGGATTGAAA	TCATTCTTAATTGTGTTAACTCTAAAAACGTCTCC
GTCGCACTCTATATGAGTGCGTGGATTGAAA	TTAAGTATGGATGGCGAAATCTAAACGGGACGAGTAGGG
GTCGCACTCTGTATGGAGTGCGTGGATTGAA	ATTGCATTAGATGAGTGATCACGTTCGGCCTTACTATA
GTCGCACTCTGTATGGAGTGCGTGGATTGAA	ATAGACGTAAGCCACCAAGCAAAGAAACAATTCTCCCAGG
GTCGCACTCTGTATGGAGTGTGTGGATTGAA	ATTATTACGTTCGTGAGTTTGGTGATTCTGTCGCTCTG
GTCGCACTCTGTATGGGGTGCGTGGATTGAA	ATGACACAAGAATTCGACAGACAGGAAGGAATTTCC
GTCGCACTCTGTATGGAGTGCGTGGATTGAA	ATTCGAACATGAACACGCGTGGTATCTCCCCGTCGAC
GTCGCACTCTGTATAGAGTGAGTGGATTGAA

>NZ_CP015423|1|1|5114069-5114437|CRISPRCasFinder
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GCTTCGGAATCGGTCAAACGCCAGTGTGGGCCAAGCC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCATTAACCACGGTCGATTGATCGTAACACCTAAAC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCTCCATGCAACGGCCTGATAGTGACGTGCTGGA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GATCTGGTTGTCCTCGACATCCGCGGTGGATATAGA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CATTCTTAATTGTGTTAACTCTAAAAACGTCTCC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015423.1\|WP_061829391.1\|5123072_5124467_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NZ_CP015423.1\|WP_061829393.1\|5117741_5118926_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|181082
NZ_CP015423.1\|WP_061829394.1\|5116810_5117740_+\|D-alanine--D-alanine-ligase	unknown	unknown	gnl\|CDD\|234948
NZ_CP015423.1\|WP_061829403.1\|5112726_5113536_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235546
NZ_CP015423.1\|WP_061829395.1\|5115217_5116702_+\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NZ_CP015423.1\|WP_069291751.1\|5127174_5129703_+\|ATP-dependent-helicase-HrpB	unknown	unknown	gnl\|CDD\|273901
NZ_CP015423.1\|WP_061829406.1\|5102608_5106604_+\|type-VII-secretion-protein-EssC	unknown	unknown	gnl\|CDD\|274860
NZ_CP015423.1\|WP_061829390.1\|5125423_5125798_+\|DUF1992-domain-containing-protein	unknown	unknown	gnl\|CDD\|182303
NZ_CP015423.1\|WP_061829405.1\|5106620_5107463_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015423.1\|WP_013309990.1\|5108254_5108530_+\|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl\|CDD\|274862
NZ_CP015423.1\|WP_013370782.1\|5101591_5101831_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015423.1\|WP_061829458.1\|5107468_5108005_+\|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl\|CDD\|274862
NZ_CP015423.1\|WP_013309993.1\|5111626_5112463_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238083
NZ_CP015423.1\|WP_023988263.1\|5102220_5102541_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015423.1\|WP_013309992.1\|5110861_5111614_+\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|238119
NZ_CP015423.1\|WP_061829389.1\|5125862_5126858_-\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	unknown	unknown	gnl\|CDD\|235573
NZ_CP015423.1\|WP_061829404.1\|5108731_5110777_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236545
NZ_CP015423.1\|WP_061829457.1\|5125104_5125299_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015423.1\|WP_081330748.1\|5124831_5124999_+\|aspartyl-phosphate-phosphatase-Spo0E-family-protein	unknown	unknown	gnl\|CDD\|378175
NZ_CP015423.1\|WP_061829392.1\|5122557_5122740_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP015423.1\|WP_061829391.1\|5123072_5124467_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	2.60592e-05
NZ_CP015423.1\|WP_061829393.1\|5117741_5118926_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|181082	PRK07682, PRK07682, aminotransferase.	0
NZ_CP015423.1\|WP_061829403.1\|5112726_5113536_+\|SDR-family-oxidoreductase	gnl\|CDD\|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	1.58759e-90
NZ_CP015423.1\|WP_061829395.1\|5115217_5116702_+\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	6.30456e-125
NZ_CP015423.1\|WP_069291751.1\|5127174_5129703_+\|ATP-dependent-helicase-HrpB	gnl\|CDD\|273901	TIGR01970, ATP-dependent_RNA_helicase_HrpB, ATP-dependent helicase HrpB. This model represents HrpB, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria, but also in a few species of other lineages. The member from Rhizobium meliloti has been designated HelO. HrpB is typically about 800 residues in length, while its paralog HrpA (TIGR01967), also uncharacterized, is about 1300 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP015423.1\|WP_061829406.1\|5102608_5106604_+\|type-VII-secretion-protein-EssC	gnl\|CDD\|274860	TIGR03928, T7_EssCb_Firm, type VII secretion protein EssC, C-terminal domain. This model describes the C-terminal domain, or longer subunit, of the Firmicutes type VII secretion protein EssC. This protein (homologous to EccC in Actinobacteria) and the WXG100 target proteins are the only homologous parts of type VII secretion between Firmicutes and Actinobacteria. [Protein fate, Protein and peptide secretion and trafficking].	0
NZ_CP015423.1\|WP_061829394.1\|5116810_5117740_+\|D-alanine--D-alanine-ligase	gnl\|CDD\|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	1.62528e-143
NZ_CP015423.1\|WP_013309990.1\|5108254_5108530_+\|WXG100-family-type-VII-secretion-target	gnl\|CDD\|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	4.19531e-14
NZ_CP015423.1\|WP_061829458.1\|5107468_5108005_+\|WXG100-family-type-VII-secretion-target	gnl\|CDD\|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	4.44504e-06
NZ_CP015423.1\|WP_013309993.1\|5111626_5112463_+\|hypothetical-protein	gnl\|CDD\|238083	cd00143, PP2Cc, Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence similarity.	0.00422194
NZ_CP015423.1\|WP_013309992.1\|5110861_5111614_+\|VWA-domain-containing-protein	gnl\|CDD\|238119	cd00198, vWFA, Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains.	8.50689e-08
NZ_CP015423.1\|WP_061829389.1\|5125862_5126858_-\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	gnl\|CDD\|235573	PRK05710, PRK05710, tRNA glutamyl-Q(34) synthetase GluQRS.	2.6473e-114
NZ_CP015423.1\|WP_061829404.1\|5108731_5110777_+\|hypothetical-protein	gnl\|CDD\|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	2.7195e-12
NZ_CP015423.1\|WP_081330748.1\|5124831_5124999_+\|aspartyl-phosphate-phosphatase-Spo0E-family-protein	gnl\|CDD\|378175	pfam09388, SpoOE-like, Spo0E like sporulation regulatory protein. Spore formation is an extreme response to starvation and can also be a component of disease transmission. Sporulation is controlled by an expanded two-component system where starvation signals result in sensor kinase activation and phosphorylation of the master sporulation response regulator Spo0A. Phosphatases such as Spo0E dephosphorylate Spo0A thereby inhibiting sporulation. This is a family of Spo0E-like phosphatases. The structure of a Bacillus anthracis member of this family has revealed an anti-parallel alpha-helical structure.	4.856e-08
NZ_CP015423.1\|WP_061829390.1\|5125423_5125798_+\|DUF1992-domain-containing-protein	gnl\|CDD\|182303	PRK10203, PRK10203, hypothetical protein; Provisional.	1.02521e-32

>NZ_CP015423.1|WP_061829403.1|5112726_5113536_+|SDR-family-oxidoreductase
MSYTYAGGARFEGKTALITGAGSGIGKATAIQMAREGANVALFDVSNERISETEREINAIREGSARAFDVDIADPVRVEKAVLEAVELFGGLHIIFANAGINGVVGPIEDLSIEDWRQTLSTNLDGTFLTVKYTIPHLKKNGGGSIIITSSINGNQRFTSFGMSAYSTSKAGQTGFAKMAALELAKFRIRVNVIYPGAISTNIDETTEKSEGLKQITIPVKFPEGGQPLADGPGQPEQVADLVTFLASDHSRHITGAQIVIDGAESLLF
>NZ_CP015423.1|WP_013309993.1|5111626_5112463_+|hypothetical-protein
MNPLLSLLPASKKKGMNARLTQQFAYISSQTGDQPLSSHHSRFMCRYGYGRSAESASMGESGQDFAAVRIHKSVCCFVLCDGVGLSYRGDFAARYLGSSLLDWMERGQDLSADQLRVYLERLAGTAAEELDRQPLDHESGLMRSVLEDKRRQGSQSMYICGKIELPKRGSRGRLRLAWQGDSRLRLWNGAEEISELFDHTFSTAERWSTSRGPIGGKPHWYERSIPADMPMRLQVYTDGLSDLDPIREPVPDEQIQVLLDASHTGGLDDDAAFIELQW
>NZ_CP015423.1|WP_013309992.1|5110861_5111614_+|VWA-domain-containing-protein
MNYTIQASQRTPALIIYLIDISASMNMLMEGRRRIDVVYEAISLAIRQMVFRSTKGNRLTARYRIAILAYSDDVYDLLNGVKGIDEIAAIGSLPDLTPKRFSDSAKAFLQAERILQAELPGMQDCPAPLVCHMTDGVSTGDDPEPIAKRIMSMSVPDGNVLVENIFLSDRLLETPIQDPRRWKGLTHNTPLQDEHAVKLRDMSSVLPESYREMLFEADYQLGEGAIMMLPGTCAELVSIGFQMSAATPVR
>NZ_CP015423.1|WP_061829404.1|5108731_5110777_+|hypothetical-protein
MSFQPNPGDELIINGTAYVVGRHPAAPGLAYAQAGRQGIVYQLNAKNGAPHEAKALKVFFPKFRIPAMVYQSEHMEAYGDIPGLQVCKRDVLTPERNGSLIAEQPDLLYAVLMPWVHGMTWFDCLTDQRQLEASDSLALARALAGIGSAMEQKGLAHCDLSAPNVMLPFFSEVELPQGTSAVELVDVEQMYSTKMDRPDALLAGSPGYAAHRTVHSGLWSAYADRFAGAIIIGEMLGWSDRVVVDKAWGESYFDQHEMQTPCERYFILRKSLESRWGSKVVELFSRAWDSQDLSSCPTFGEWLVVLNAVTEQEIPVEAIEPEPAATETIESAAVGGLASEAAPSLSAPAPLKAEQAALLNQAALEQGERGVTDKLFRQARDLEQQNKPAAALEVYRSLYHFVEDGSPLHVEVSAAITGLEEQLNPKTPEQPEKSKAWYRSKAFIVTTAAAVVVLAAGIPAVNILADQSNQRQIEAAKQEEAAKAAKAAEEKLAAEQEAAQKLLTEKQRQEAEQQTKQQALAAQKQQEEQKKQQALIAQQVKYEAYLAQKEQNKQAAAKLAKQKAYDQQAKYEKYLALKKEQEARAAQEEAARKAAAEAEQKQKESMHARNKENVLQLISLYNKAYASQEGGSAAKAKSFAKRFRTLYDSNPSYYRSVGEVGYRASSIYNFLGDTNFRLPKI
>NZ_CP015423.1|WP_013309990.1|5108254_5108530_+|WXG100-family-type-VII-secretion-target
MAGRILITPEQVDQVANQFKQSGEQSQQIVSSLTQSISGMEGQWEGMTKQRFFQEFQEASKQMQAFVTTLNSISQELTAIANKFRTVDQTK
>NZ_CP015423.1|WP_061829458.1|5107468_5108005_+|WXG100-family-type-VII-secretion-target
MRIRVEPDVLRGLSGQLQHAAEQIQQLTAGLEQALQSLDWDVSAREAILNHWMQAKRMSEQIHAYLHTSGTQLNRKAEQFQSVDHNYQTILSFASQPLGRPVTMLDWSNQQSPSILPGQASEGGSLISNPQSVVHAIAGVQSSDIETLHQDILMQASSSSPQDWYFTDPSTARDQPVA
>NZ_CP015423.1|WP_061829405.1|5106620_5107463_+|hypothetical-protein
MLTFQASKQKLITLKAKELFFLAGVLGSDRLLGVEDPFKGYLAEELAEEWEQVKATLLEKGYLKRADKGKELAMPPTVFSRVAIAGLSNRACRIRYVRGGKQFEGYLHCTNERVVELVKSADEPDEYRLYDLGNVEKACETLVDKMGWVDRLMPESPALMFSKQAFNKIYEQSAGESVSLISSKLTEASGDAEGSASLAQSLSSRVAEGELQLLVWNGREWESQRAAFVLCPAMNWIFRMSSSGNGDWLIAAMASRDQFVDLLLNWLKQSAVNEEVTEEG
>NZ_CP015423.1|WP_061829406.1|5102608_5106604_+|type-VII-secretion-protein-EssC
MNALYQRSPRLRPALREEKLEILRPPAEPSKPSFSIISILIPLMMTLVTIGFYVYMSKTGKMGNSNYLMFQMVTVVMMLTSYTIPFFVYLNNKKEYKRKLEERDRMYREQLQKHREELEMKREEQIRTLYEIHGDPQICTQIVKNRNSSLWERSPEDEDFLQVRIGTGQVPFHIKLQIPRPDGYDRDPLLGAADELEEEFRLVDAASIALPLFQSKVVGLVGEREHTLAALRVILAQVTVRHSPDEVKIASFYDEREESEWTWMRWLPHVWDDDRIQRMMSDRSSSAHQLADFLFARLNRRKNNRNDRQGRGMEVPCYVVVLSDTQLIEEEPLLPLLLEDGRAIDACTIVLASRKEALPMQCQLIVEASKEQGVYARKSESAEVEQQSFKPDRLSKEEADALARYMAPIRLKRSSASDIPAVLPLFDMMSVASVAELDVADRWRRNRHPDTLPVPMGVRAGGKKIMINLHDKIERQGHGPHGLIAGTTGSGKSEVIQSIVASLAAEFHPHDLAFMLIDYKGGGMSNTFVNLPHVVGTITNLDNNLIERAKISLKAELVRRQKILNDAGNLQHIDEYYRLLRQRQEQPLPHLVIIIDEFAQLKRDQPEFMDELISIAAIGRTLGVHLILATQKPAGVVDDKIWSNSRFRICLRVQSEGDSRDMLKIPNAAWITKPGRGYFQVGSDEVFEELQFAWSGAPYIGNSDISSALPVHEVRLNGKREALLTGGERASSGLKGEEAPKQLQVFIDYIANEAAKAGIERLQGPWLPPLPELLDLTNLPACTEIDSTSSSLELKALMGLVDDLPNQRQEPIYASLDHGHWAVYGMPGMGKTTFLHTLLMSTAQRFTANHWNGYIIDMGRTMRDFGELPQIGAVMMAEEDDRIKRLFRYLFKMVAVRKEMLSEAGVKTISSYRRSAVEDIPQIVVVIDGYLNFRNAYPDENELLESLLREGGSLGITFIITANRITDVFEKFRSNIPNAVSFEMSDPSDYYYAVGRPAKTPGPLIPGRALVKGHVPPLEFQTALPSPGEDETERSARLRRNIAGIAQEWKGKHAPAILPLPERIPLSELLQQWDQTSGPSGALPYEVPVGLQSDDLEPFLLNLKEGPNFIVGSPMEGGKTSFLMSWIISLAYYTSPNQLEVYTIDTRYGGGGLSRLRHLPHVKAAAESEEEMGPLVQKVYDIVQQRNKEGNDPELLLVIDDADMLSKQLNDFMIKDQLSAIVRLGRDRNVHVVLSGVPSDFPTFGVDWFNDVKASQSGMLFGTLDSNDLSFFRIPYSEANAAAGGLKVLPPGQGYYVRRKFTRIKAAIPFSEQVSCEDWITKIRDRWHVVV
>NZ_CP015423.1|WP_023988263.1|5102220_5102541_+|hypothetical-protein
MILTVLSGRQETEWFDIEVADEYSVEHLKLMLGVRIFGEPPAEGMQYIMEAKFPEGLWFRVGDNQLLTGSGLREGCTVRIQRAFSTTQDEAPVYGRRSLFQSEKNG
>NZ_CP015423.1|WP_013370782.1|5101591_5101831_-|hypothetical-protein
MRTLITFQNKRIPVYFNQENKQPVQKTLKLLSNTLENKISSGKRALQKCLNSLISIEIVGCEAILHSVSENDSLALSLY
>NZ_CP015423.1|WP_061829395.1|5115217_5116702_+|PLP-dependent-aminotransferase-family-protein
MFQDFKLVSDRPVSIQVKEYVNRLIIKGALQADQKLPSTREMSVLLKVSRNTVIAAYEGLEDDGFTYAIPGKGSYVAAMVGQSAVDNGGSDGSATWEIDWKARMNEYAVLAVDLDMMKQGIRAQKGTISFTSIAPDEQLFDLGDVRRAFMDRMAIEGQVLLNYGYAKGYKPLIDYLMHYMENKGVDIIGKDMLITGGFTEGFDIVLSALRPSARRGAAICENPTHHTAIKNLKLQGFEITGIPMECDGIDVERLEEVLQTNSFDLAYLTPSYHNPTGIVMSPAKRSAVMKLMMSYQIPVIEDGFNEELRYSGAHIAPLIATAGQGNGVIYIGSFSKVLFPGLRVGWVLGDRALIDTLESIKRARTIHTSTIDQSILYQYMLNGNFDKHVKKARTEYKRKYELTKTCCEAHLPEAQVSGDGGLHLFLTFPTGVNTRQLLEACTEQGVIFTPGDKFFIQEGEGTNTLRLGFSRVTDENIERGIQIIGKQTRKFLKA
>NZ_CP015423.1|WP_061829394.1|5116810_5117740_+|D-alanine--D-alanine-ligase
MKIGVIMGGISSEREISLQTGQEMINHLDRSRYEVVPMVIEQRADLIAQVQQAGIDIALLALHGQYGEDGTVQGALETLGIPYTGSGVLASSLCMNKQLSKMLLKAAGVHTPSGLYWQGMDDYDPQVVEHLGYPVIVKPNMGGSSIGIQLVQNEKELLPAVQEACSLDQAILIEPYYEGTEITCSIVDGEVLPIISISSARSKWFDYKAKYEVGGAEEKVIELPPVIEQRVREAALSSYRLLQCKVYARIDMILCQDRPYVLEVNTLPGMTANSLLPKSAAAAGITFTQLLDQIIASSLHERKQEWRMA
>NZ_CP015423.1|WP_061829393.1|5117741_5118926_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MFSEMGTGRFVSSRVRDIRPSGIRAFFDLNAAGGGTIALGVGEPDFVTPDKVREACIQALREGQTKYTSNAGLMELREEISAYFSGSFALSYDPEQEMIVTVGSSEAVDLALRAVIDPGDEVLIPAPSYIAYEPITHLHGGKIVEVAATAEEQFKLTPQALQAAITPHSKVLMINYPCNPTGTVMTEQDWLPITELIIKHNLVVISDEVYAELTYGRKHVSIASLPGMKERTIVISGFSKAFAMTGWRVGYACGPHELIAGMLKIHQYTAMCAPTIAQIAALESLRHGLAAKDEMMASYNERRKLFVAGLNAIGLACHEPEGAFYAFPSITSTGMSSEQFALRMLKEAKVAVVPGHVFGSGGEGFIRCSYAASLVDLEKALKRMGRFMQVMQPV
>NZ_CP015423.1|WP_061829392.1|5122557_5122740_+|hypothetical-protein
MRISMSKFLKRYAAILLGYAICIGLFYALGYKMSAMGIYAILTGIVTGEIINFVLSKREK
>NZ_CP015423.1|WP_061829391.1|5123072_5124467_+|helix-turn-helix-transcriptional-regulator
MKHTPTISAEFEDYLKQNDMTLSQFAEYSGVHQRTLSHWITQHRPVSIQQLDRITVAMDLPEGYFYDLYIENYIIDLSPNFRRIEPLLYRCAELDKLDAIRRMVGHIMDNPLYATRLFDVAEALFEQGRHAAALPLYENVAEVEKYQHSERLATCQYRIFSIQVGDDQSRNLKAATLFEPFVERLDEIDQLDALKDLANVYRSLRLWDRLDVTARKMRDKAEIQYTLEHQQKKRKSAEIEKRLSRPLFVYITYADLLCASVCEAQGDYQQALQYTYAYVNLDWVKETDEDTLHWIKLFQNWALCNTYVNKLLSGDISVLPDYVEYISVSSNTTKEMVTQLLNIMMAANRFQVDVDEVLKQFETEIDSITQQQPSADMYTHRVVPEQLTRFKYELAKYYLNKGNYSYGFKNLLDVLSKSLVINKEAFFISCIRLFEQFKQFADFRLCTKYESLVREGRKERLFYY
>NZ_CP015423.1|WP_081330748.1|5124831_5124999_+|aspartyl-phosphate-phosphatase-Spo0E-family-protein
MLMNPGVTLLRVERARKRLYQIQKKYGFLTHPKVIEQSMKLDELLNQYQTCKMKS
>NZ_CP015423.1|WP_061829457.1|5125104_5125299_+|hypothetical-protein
MNKRNPVTPFGWKIKQKLVEIQMDQRTFCDTYHIPASRLSNLIHGTRKAKKYRVQVSQLLGIEE
>NZ_CP015423.1|WP_061829390.1|5125423_5125798_+|DUF1992-domain-containing-protein
MGMFSRMAEQKIAEAMAKGEFDHLPGEGKPLVIEDLSHVPEELRMSYKLLKNAGILPEELQLQKECVQLRDLLHACHEAGERERISRRLTEKSLRLRMLLEERGLNTSSVFYEYESAMRKRLEE
>NZ_CP015423.1|WP_061829389.1|5125862_5126858_-|tRNA-glutamyl-Q(34)-synthetase-GluQRS
MELQAQPIRGRFAPTPSGWIHLGNARTALLSWLHVRSLGGTYILRMEDIDMTRARSQLAQGIMEDLRWIGLNWDEGPDVGGPYGSYTQSQRLERYQSALEKLQRQDLLYPCFCSRADILAAAHAPHGLSGEGPAYSGACRNLSFQDVVAKAQYKLPSLRFKVPQYPDAVISFHDQVAGHVAFGAAEGGDFIVKRADGMFSYQLAVVIDDADMHMTDVLRGYDLLDSTPRQLLLYQAFGLQPPRFAHVPLVLGPDGRRLAKRHGGVALRAMRRQGVTPEAVIGWLAYFSGLLDSPEPVKAEDLIDDFHLDKLPKEPVILTKQCLTRLSALQR
>NZ_CP015423.1|WP_069291751.1|5127174_5129703_+|ATP-dependent-helicase-HrpB
MTDKQLPIMQVIPELKHTLQSHSAAVLIAQPGAGKTTVTPLELLHEPWLAGQKMMMLEPRRLAARAAAAQMAKALGEPTGKTVGYRVRMDTKVGPNTRIEVVTEGVLTRMLQHDQALEGVGLIIFDEFHERSLHADLGLALALQSQALLRPDLKILIMSATLEAEPVCRLLGDAPLLECPGTVFPVETFHMSKPSSTSLESFTAETVEKVLHTSEGDLLVFLPGAREIHRTERELASKHLPAHVKVIPLYGSMKLEQQDEAIRPSASGSRKVVLATSIAESSLTIAGITVVIDSGLSRESVFSARTGMSRLTTVKVSKASADQRRGRAGRLQPGVCYRLWSAQEQAALPDASRPEIAAADLAPLALELAAWGVREPAELAWLDAPPEAAYRQATGLLHQLGCLDEAADGTTGSITAHGREVSALGTHPRLGHMLLRATALGLAPTASRLAALLQERDPFRAHGGTDLRPRLDALREAAYARSTHSLLRAADDTVIRRIVQESRQLLAKLPTAAAAQDEPDGSAACGLLLAFAYPDRIAQGRGDGRFLLSGGRGARLGQVEWMSRSSYLVAAEVDDEGADGAIQLAAPIELQELVEHCSEMLLEQANVYWDSSASAVRARKVLRLGSLVLKETSYERPPAEEVAAALMQGVRERGLKLLSWNRQTLQLQARLIFMHFSAPEDWPDCTESALLDSLEAWLLPFAIGAKNVSDLQRLDSAALLLGRLDWEQRQQLDQEAPTHIRVPSGSRIPVDYSNPEAPALAVRLQELFGMGDTPRIGRGRVPIVLHLLSPAQRPVQVTSDLSSFWSEAYFEVKKDLKGRYPKHYWPDDPLEAVATNRAKPKR

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Crispr_ID: NZ_CP015423_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015423_2

5119410-5120450

Orphan

NA:I-C

Consensus_repeat	Method
GTCGCACTCTATAT-GAGTGCGTGGATTGAAAT	PILER-CR
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CRT

15 spacers

The CRISPR arrays of NZ_CP015423_2

>merge|NZ_CP015423|2|5119410-5120450|PILER-CR,CRISPRCasFinder,CRT
GTCGCACTCTATATGAGTGCGTGGATTGAAATTTTGTTCCTCGCTCAGCATGCGGATCAGGTGTATGGTCGCACTCTATATGAGTGCGTGGATTGAAATTGAGTCGTCCATTGTAAGAATGCATGTTGAGTATCCGTCGCACTCTATATGAGTGCGTGGATTGAAATTTTGCAGTACTTAGGAGTCCAAATGTAAAAGGAAGTCGCACTCTATATGAGTGCGTGGATTGAAATTGATATAGATGATTGGTCGCATGTATGATATCTCGTCGCACTCTATATGAGTGCGTGGATTGAAATACTGAGCAACCACTTCAATTGCATGTTCCTCTTCTGGTCGCACTCTATATGAGTGCGTGGATTGAAATATTTTAAAGTTGATCCAATGGCTATGATAAAAATGTCGCACTCTATATGAGTGCGTGGATTGAAATAACACTACAATCACACGAGCAAAAGTCTTGTTCGCGTCGCACTCTATATGAGTGCGTGGATTGAAATATATTGCGTTTTACAGTAGAAATTATCTTGCATGCCAGTCGCACTCTATATGAGTGCGTGGATTGAAATATCGACATAGAGGTGGACGATTACCATATCCTCGGTCGCACTCTATATGAGTGCGTGGATTGAAATTTCAAGGGCTATCGTACACGGCTTGAGGACGCAGTTTCGTCGCACTCTATATGAGTGCGTGGATTGAAATTGTGCTGTCCTGGCGCACCCTTAACTCGCTTACCTGTCGCACTCTATATGAGTGCGTGGATTGAAATCAATACCGAAATGATGGGGGGTGGAATTATTAAAGTCGCACTCTATATGAGTGCGTGGATTGAAATGGATCAGGAGCAATGGGCATAGCATCCGGTTCAGTCGCACTCTATATGAGTGCGTGGATTGAAATGCGTATCCAGACGGTTTATGCTCGGTGTAGCAAAGAGTCGCACTCTATATGAGTGCGTGGATTGAAATATCAAATGACACGCCAGCACTGGCAGGGCATCCCGCAGTCGCACTCTATATGAGTGCGTGGATCATGACG

>NZ_CP015423|2|2|5119410-5120380|PILER-CR
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTTGTTCCTCGCTCAGCATGCGGATCAGGTGTATG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGAGTCGTCCATTGTAAGAATGCATGTTGAGTATCC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTTGCAGTACTTAGGAGTCCAAATGTAAAAGGAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGATATAGATGATTGGTCGCATGTATGATATCTC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ACTGAGCAACCACTTCAATTGCATGTTCCTCTTCTG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATTTTAAAGTTGATCCAATGGCTATGATAAAAAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AACACTACAATCACACGAGCAAAAGTCTTGTTCGC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATATTGCGTTTTACAGTAGAAATTATCTTGCATGCCA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCGACATAGAGGTGGACGATTACCATATCCTCG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTCAAGGGCTATCGTACACGGCTTGAGGACGCAGTTTC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGTGCTGTCCTGGCGCACCCTTAACTCGCTTACCT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CAATACCGAAATGATGGGGGGTGGAATTATTAAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GGATCAGGAGCAATGGGCATAGCATCCGGTTCA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GCGTATCCAGACGGTTTATGCTCGGTGTAGCAAAGA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT

>NZ_CP015423|2|2|5119410-5120450|CRISPRCasFinder
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTTGTTCCTCGCTCAGCATGCGGATCAGGTGTATG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGAGTCGTCCATTGTAAGAATGCATGTTGAGTATCC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTTGCAGTACTTAGGAGTCCAAATGTAAAAGGAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGATATAGATGATTGGTCGCATGTATGATATCTC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ACTGAGCAACCACTTCAATTGCATGTTCCTCTTCTG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATTTTAAAGTTGATCCAATGGCTATGATAAAAAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AACACTACAATCACACGAGCAAAAGTCTTGTTCGC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATATTGCGTTTTACAGTAGAAATTATCTTGCATGCCA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCGACATAGAGGTGGACGATTACCATATCCTCG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTCAAGGGCTATCGTACACGGCTTGAGGACGCAGTTTC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGTGCTGTCCTGGCGCACCCTTAACTCGCTTACCT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CAATACCGAAATGATGGGGGGTGGAATTATTAAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GGATCAGGAGCAATGGGCATAGCATCCGGTTCA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GCGTATCCAGACGGTTTATGCTCGGTGTAGCAAAGA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCAAATGACACGCCAGCACTGGCAGGGCATCCCGCA
GTCGCACTCTATATGAGTGCGTGGATCATGACG

>NZ_CP015423|2|2|5119410-5120449|CRT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTTGTTCCTCGCTCAGCATGCGGATCAGGTGTATG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGAGTCGTCCATTGTAAGAATGCATGTTGAGTATCC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTTGCAGTACTTAGGAGTCCAAATGTAAAAGGAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGATATAGATGATTGGTCGCATGTATGATATCTC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ACTGAGCAACCACTTCAATTGCATGTTCCTCTTCTG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATTTTAAAGTTGATCCAATGGCTATGATAAAAAT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AACACTACAATCACACGAGCAAAAGTCTTGTTCGC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATATTGCGTTTTACAGTAGAAATTATCTTGCATGCCA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCGACATAGAGGTGGACGATTACCATATCCTCG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTCAAGGGCTATCGTACACGGCTTGAGGACGCAGTTTC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGTGCTGTCCTGGCGCACCCTTAACTCGCTTACCT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CAATACCGAAATGATGGGGGGTGGAATTATTAAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GGATCAGGAGCAATGGGCATAGCATCCGGTTCA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GCGTATCCAGACGGTTTATGCTCGGTGTAGCAAAGA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATCAAATGACACGCCAGCACTGGCAGGGCATCCCGCA
GTCGCACTCTATATGAGTGCGTGGATCATGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015423.1\|WP_061830310.1\|5129821_5130409_+\|general-stress-protein	unknown	unknown	gnl\|CDD\|378584
NZ_CP015423.1\|WP_061829391.1\|5123072_5124467_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NZ_CP015423.1\|WP_061829393.1\|5117741_5118926_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|181082
NZ_CP015423.1\|WP_061829403.1\|5112726_5113536_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235546
NZ_CP015423.1\|WP_061829395.1\|5115217_5116702_+\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NZ_CP015423.1\|WP_061830311.1\|5130679_5131852_+\|acyltransferase	unknown	unknown	gnl\|CDD\|376607
NZ_CP015423.1\|WP_069291751.1\|5127174_5129703_+\|ATP-dependent-helicase-HrpB	unknown	unknown	gnl\|CDD\|273901
NZ_CP015423.1\|WP_155765263.1\|5114029_5114176_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015423.1\|WP_061829394.1\|5116810_5117740_+\|D-alanine--D-alanine-ligase	unknown	unknown	gnl\|CDD\|234948
NZ_CP015423.1\|WP_013309990.1\|5108254_5108530_+\|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl\|CDD\|274862
NZ_CP015423.1\|WP_061829457.1\|5125104_5125299_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015423.1\|WP_061829458.1\|5107468_5108005_+\|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl\|CDD\|274862
NZ_CP015423.1\|WP_013309993.1\|5111626_5112463_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238083
NZ_CP015423.1\|WP_069291752.1\|5131994_5132639_+\|CatB-related-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100040
NZ_CP015423.1\|WP_013309992.1\|5110861_5111614_+\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|238119
NZ_CP015423.1\|WP_061829389.1\|5125862_5126858_-\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	unknown	unknown	gnl\|CDD\|235573
NZ_CP015423.1\|WP_061829404.1\|5108731_5110777_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236545
NZ_CP015423.1\|WP_081330748.1\|5124831_5124999_+\|aspartyl-phosphate-phosphatase-Spo0E-family-protein	unknown	unknown	gnl\|CDD\|378175
NZ_CP015423.1\|WP_061829390.1\|5125423_5125798_+\|DUF1992-domain-containing-protein	unknown	unknown	gnl\|CDD\|182303
NZ_CP015423.1\|WP_061829392.1\|5122557_5122740_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP015423.1\|WP_061829391.1\|5123072_5124467_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	2.60592e-05
NZ_CP015423.1\|WP_061829393.1\|5117741_5118926_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|181082	PRK07682, PRK07682, aminotransferase.	0
NZ_CP015423.1\|WP_061829403.1\|5112726_5113536_+\|SDR-family-oxidoreductase	gnl\|CDD\|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	1.58759e-90
NZ_CP015423.1\|WP_061829395.1\|5115217_5116702_+\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	6.30456e-125
NZ_CP015423.1\|WP_069291751.1\|5127174_5129703_+\|ATP-dependent-helicase-HrpB	gnl\|CDD\|273901	TIGR01970, ATP-dependent_RNA_helicase_HrpB, ATP-dependent helicase HrpB. This model represents HrpB, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria, but also in a few species of other lineages. The member from Rhizobium meliloti has been designated HelO. HrpB is typically about 800 residues in length, while its paralog HrpA (TIGR01967), also uncharacterized, is about 1300 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP015423.1\|WP_061830311.1\|5130679_5131852_+\|acyltransferase	gnl\|CDD\|376607	pfam01757, Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes. This domain is found in many as yet uncharacterized C. elegans proteins and it is approximately 300 amino acids long.	2.32348e-17
NZ_CP015423.1\|WP_061829394.1\|5116810_5117740_+\|D-alanine--D-alanine-ligase	gnl\|CDD\|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	1.62528e-143
NZ_CP015423.1\|WP_013309990.1\|5108254_5108530_+\|WXG100-family-type-VII-secretion-target	gnl\|CDD\|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	4.19531e-14
NZ_CP015423.1\|WP_061829458.1\|5107468_5108005_+\|WXG100-family-type-VII-secretion-target	gnl\|CDD\|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	4.44504e-06
NZ_CP015423.1\|WP_013309993.1\|5111626_5112463_+\|hypothetical-protein	gnl\|CDD\|238083	cd00143, PP2Cc, Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence similarity.	0.00422194
NZ_CP015423.1\|WP_069291752.1\|5131994_5132639_+\|CatB-related-O-acetyltransferase	gnl\|CDD\|100040	cd03349, LbH_XAT, Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. Members of this class of enzymes include Enterococcus faecium streptogramin A acetyltransferase and Pseudomonas aeruginosa chloramphenicol acetyltransferase. They contain repeated copies of a six-residue hexapeptide repeat sequence motif (X-[STAV]-X-[LIV]-[GAED]-X) and adopt a left-handed parallel beta helix (LbH) structure. The active enzyme is a trimer with CoA and substrate binding sites at the interface of two separate LbH subunits. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients.	5.45542e-75
NZ_CP015423.1\|WP_013309992.1\|5110861_5111614_+\|VWA-domain-containing-protein	gnl\|CDD\|238119	cd00198, vWFA, Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains.	8.50689e-08
NZ_CP015423.1\|WP_061829389.1\|5125862_5126858_-\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	gnl\|CDD\|235573	PRK05710, PRK05710, tRNA glutamyl-Q(34) synthetase GluQRS.	2.6473e-114
NZ_CP015423.1\|WP_061829404.1\|5108731_5110777_+\|hypothetical-protein	gnl\|CDD\|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	2.7195e-12
NZ_CP015423.1\|WP_081330748.1\|5124831_5124999_+\|aspartyl-phosphate-phosphatase-Spo0E-family-protein	gnl\|CDD\|378175	pfam09388, SpoOE-like, Spo0E like sporulation regulatory protein. Spore formation is an extreme response to starvation and can also be a component of disease transmission. Sporulation is controlled by an expanded two-component system where starvation signals result in sensor kinase activation and phosphorylation of the master sporulation response regulator Spo0A. Phosphatases such as Spo0E dephosphorylate Spo0A thereby inhibiting sporulation. This is a family of Spo0E-like phosphatases. The structure of a Bacillus anthracis member of this family has revealed an anti-parallel alpha-helical structure.	4.856e-08
NZ_CP015423.1\|WP_061829390.1\|5125423_5125798_+\|DUF1992-domain-containing-protein	gnl\|CDD\|182303	PRK10203, PRK10203, hypothetical protein; Provisional.	1.02521e-32
NZ_CP015423.1\|WP_061830310.1\|5129821_5130409_+\|general-stress-protein	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	1.04325e-12

>NZ_CP015423.1|WP_061829393.1|5117741_5118926_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MFSEMGTGRFVSSRVRDIRPSGIRAFFDLNAAGGGTIALGVGEPDFVTPDKVREACIQALREGQTKYTSNAGLMELREEISAYFSGSFALSYDPEQEMIVTVGSSEAVDLALRAVIDPGDEVLIPAPSYIAYEPITHLHGGKIVEVAATAEEQFKLTPQALQAAITPHSKVLMINYPCNPTGTVMTEQDWLPITELIIKHNLVVISDEVYAELTYGRKHVSIASLPGMKERTIVISGFSKAFAMTGWRVGYACGPHELIAGMLKIHQYTAMCAPTIAQIAALESLRHGLAAKDEMMASYNERRKLFVAGLNAIGLACHEPEGAFYAFPSITSTGMSSEQFALRMLKEAKVAVVPGHVFGSGGEGFIRCSYAASLVDLEKALKRMGRFMQVMQPV
>NZ_CP015423.1|WP_061829394.1|5116810_5117740_+|D-alanine--D-alanine-ligase
MKIGVIMGGISSEREISLQTGQEMINHLDRSRYEVVPMVIEQRADLIAQVQQAGIDIALLALHGQYGEDGTVQGALETLGIPYTGSGVLASSLCMNKQLSKMLLKAAGVHTPSGLYWQGMDDYDPQVVEHLGYPVIVKPNMGGSSIGIQLVQNEKELLPAVQEACSLDQAILIEPYYEGTEITCSIVDGEVLPIISISSARSKWFDYKAKYEVGGAEEKVIELPPVIEQRVREAALSSYRLLQCKVYARIDMILCQDRPYVLEVNTLPGMTANSLLPKSAAAAGITFTQLLDQIIASSLHERKQEWRMA
>NZ_CP015423.1|WP_061829395.1|5115217_5116702_+|PLP-dependent-aminotransferase-family-protein
MFQDFKLVSDRPVSIQVKEYVNRLIIKGALQADQKLPSTREMSVLLKVSRNTVIAAYEGLEDDGFTYAIPGKGSYVAAMVGQSAVDNGGSDGSATWEIDWKARMNEYAVLAVDLDMMKQGIRAQKGTISFTSIAPDEQLFDLGDVRRAFMDRMAIEGQVLLNYGYAKGYKPLIDYLMHYMENKGVDIIGKDMLITGGFTEGFDIVLSALRPSARRGAAICENPTHHTAIKNLKLQGFEITGIPMECDGIDVERLEEVLQTNSFDLAYLTPSYHNPTGIVMSPAKRSAVMKLMMSYQIPVIEDGFNEELRYSGAHIAPLIATAGQGNGVIYIGSFSKVLFPGLRVGWVLGDRALIDTLESIKRARTIHTSTIDQSILYQYMLNGNFDKHVKKARTEYKRKYELTKTCCEAHLPEAQVSGDGGLHLFLTFPTGVNTRQLLEACTEQGVIFTPGDKFFIQEGEGTNTLRLGFSRVTDENIERGIQIIGKQTRKFLKA
>NZ_CP015423.1|WP_155765263.1|5114029_5114176_+|hypothetical-protein
MSIDLAPTAKIPVVALYMSAWIEMLRNRSNASVGQAVALYMSAWIEIH
>NZ_CP015423.1|WP_061829403.1|5112726_5113536_+|SDR-family-oxidoreductase
MSYTYAGGARFEGKTALITGAGSGIGKATAIQMAREGANVALFDVSNERISETEREINAIREGSARAFDVDIADPVRVEKAVLEAVELFGGLHIIFANAGINGVVGPIEDLSIEDWRQTLSTNLDGTFLTVKYTIPHLKKNGGGSIIITSSINGNQRFTSFGMSAYSTSKAGQTGFAKMAALELAKFRIRVNVIYPGAISTNIDETTEKSEGLKQITIPVKFPEGGQPLADGPGQPEQVADLVTFLASDHSRHITGAQIVIDGAESLLF
>NZ_CP015423.1|WP_013309993.1|5111626_5112463_+|hypothetical-protein
MNPLLSLLPASKKKGMNARLTQQFAYISSQTGDQPLSSHHSRFMCRYGYGRSAESASMGESGQDFAAVRIHKSVCCFVLCDGVGLSYRGDFAARYLGSSLLDWMERGQDLSADQLRVYLERLAGTAAEELDRQPLDHESGLMRSVLEDKRRQGSQSMYICGKIELPKRGSRGRLRLAWQGDSRLRLWNGAEEISELFDHTFSTAERWSTSRGPIGGKPHWYERSIPADMPMRLQVYTDGLSDLDPIREPVPDEQIQVLLDASHTGGLDDDAAFIELQW
>NZ_CP015423.1|WP_013309992.1|5110861_5111614_+|VWA-domain-containing-protein
MNYTIQASQRTPALIIYLIDISASMNMLMEGRRRIDVVYEAISLAIRQMVFRSTKGNRLTARYRIAILAYSDDVYDLLNGVKGIDEIAAIGSLPDLTPKRFSDSAKAFLQAERILQAELPGMQDCPAPLVCHMTDGVSTGDDPEPIAKRIMSMSVPDGNVLVENIFLSDRLLETPIQDPRRWKGLTHNTPLQDEHAVKLRDMSSVLPESYREMLFEADYQLGEGAIMMLPGTCAELVSIGFQMSAATPVR
>NZ_CP015423.1|WP_061829404.1|5108731_5110777_+|hypothetical-protein
MSFQPNPGDELIINGTAYVVGRHPAAPGLAYAQAGRQGIVYQLNAKNGAPHEAKALKVFFPKFRIPAMVYQSEHMEAYGDIPGLQVCKRDVLTPERNGSLIAEQPDLLYAVLMPWVHGMTWFDCLTDQRQLEASDSLALARALAGIGSAMEQKGLAHCDLSAPNVMLPFFSEVELPQGTSAVELVDVEQMYSTKMDRPDALLAGSPGYAAHRTVHSGLWSAYADRFAGAIIIGEMLGWSDRVVVDKAWGESYFDQHEMQTPCERYFILRKSLESRWGSKVVELFSRAWDSQDLSSCPTFGEWLVVLNAVTEQEIPVEAIEPEPAATETIESAAVGGLASEAAPSLSAPAPLKAEQAALLNQAALEQGERGVTDKLFRQARDLEQQNKPAAALEVYRSLYHFVEDGSPLHVEVSAAITGLEEQLNPKTPEQPEKSKAWYRSKAFIVTTAAAVVVLAAGIPAVNILADQSNQRQIEAAKQEEAAKAAKAAEEKLAAEQEAAQKLLTEKQRQEAEQQTKQQALAAQKQQEEQKKQQALIAQQVKYEAYLAQKEQNKQAAAKLAKQKAYDQQAKYEKYLALKKEQEARAAQEEAARKAAAEAEQKQKESMHARNKENVLQLISLYNKAYASQEGGSAAKAKSFAKRFRTLYDSNPSYYRSVGEVGYRASSIYNFLGDTNFRLPKI
>NZ_CP015423.1|WP_013309990.1|5108254_5108530_+|WXG100-family-type-VII-secretion-target
MAGRILITPEQVDQVANQFKQSGEQSQQIVSSLTQSISGMEGQWEGMTKQRFFQEFQEASKQMQAFVTTLNSISQELTAIANKFRTVDQTK
>NZ_CP015423.1|WP_061829458.1|5107468_5108005_+|WXG100-family-type-VII-secretion-target
MRIRVEPDVLRGLSGQLQHAAEQIQQLTAGLEQALQSLDWDVSAREAILNHWMQAKRMSEQIHAYLHTSGTQLNRKAEQFQSVDHNYQTILSFASQPLGRPVTMLDWSNQQSPSILPGQASEGGSLISNPQSVVHAIAGVQSSDIETLHQDILMQASSSSPQDWYFTDPSTARDQPVA
>NZ_CP015423.1|WP_061829392.1|5122557_5122740_+|hypothetical-protein
MRISMSKFLKRYAAILLGYAICIGLFYALGYKMSAMGIYAILTGIVTGEIINFVLSKREK
>NZ_CP015423.1|WP_061829391.1|5123072_5124467_+|helix-turn-helix-transcriptional-regulator
MKHTPTISAEFEDYLKQNDMTLSQFAEYSGVHQRTLSHWITQHRPVSIQQLDRITVAMDLPEGYFYDLYIENYIIDLSPNFRRIEPLLYRCAELDKLDAIRRMVGHIMDNPLYATRLFDVAEALFEQGRHAAALPLYENVAEVEKYQHSERLATCQYRIFSIQVGDDQSRNLKAATLFEPFVERLDEIDQLDALKDLANVYRSLRLWDRLDVTARKMRDKAEIQYTLEHQQKKRKSAEIEKRLSRPLFVYITYADLLCASVCEAQGDYQQALQYTYAYVNLDWVKETDEDTLHWIKLFQNWALCNTYVNKLLSGDISVLPDYVEYISVSSNTTKEMVTQLLNIMMAANRFQVDVDEVLKQFETEIDSITQQQPSADMYTHRVVPEQLTRFKYELAKYYLNKGNYSYGFKNLLDVLSKSLVINKEAFFISCIRLFEQFKQFADFRLCTKYESLVREGRKERLFYY
>NZ_CP015423.1|WP_081330748.1|5124831_5124999_+|aspartyl-phosphate-phosphatase-Spo0E-family-protein
MLMNPGVTLLRVERARKRLYQIQKKYGFLTHPKVIEQSMKLDELLNQYQTCKMKS
>NZ_CP015423.1|WP_061829457.1|5125104_5125299_+|hypothetical-protein
MNKRNPVTPFGWKIKQKLVEIQMDQRTFCDTYHIPASRLSNLIHGTRKAKKYRVQVSQLLGIEE
>NZ_CP015423.1|WP_061829390.1|5125423_5125798_+|DUF1992-domain-containing-protein
MGMFSRMAEQKIAEAMAKGEFDHLPGEGKPLVIEDLSHVPEELRMSYKLLKNAGILPEELQLQKECVQLRDLLHACHEAGERERISRRLTEKSLRLRMLLEERGLNTSSVFYEYESAMRKRLEE
>NZ_CP015423.1|WP_061829389.1|5125862_5126858_-|tRNA-glutamyl-Q(34)-synthetase-GluQRS
MELQAQPIRGRFAPTPSGWIHLGNARTALLSWLHVRSLGGTYILRMEDIDMTRARSQLAQGIMEDLRWIGLNWDEGPDVGGPYGSYTQSQRLERYQSALEKLQRQDLLYPCFCSRADILAAAHAPHGLSGEGPAYSGACRNLSFQDVVAKAQYKLPSLRFKVPQYPDAVISFHDQVAGHVAFGAAEGGDFIVKRADGMFSYQLAVVIDDADMHMTDVLRGYDLLDSTPRQLLLYQAFGLQPPRFAHVPLVLGPDGRRLAKRHGGVALRAMRRQGVTPEAVIGWLAYFSGLLDSPEPVKAEDLIDDFHLDKLPKEPVILTKQCLTRLSALQR
>NZ_CP015423.1|WP_069291751.1|5127174_5129703_+|ATP-dependent-helicase-HrpB
MTDKQLPIMQVIPELKHTLQSHSAAVLIAQPGAGKTTVTPLELLHEPWLAGQKMMMLEPRRLAARAAAAQMAKALGEPTGKTVGYRVRMDTKVGPNTRIEVVTEGVLTRMLQHDQALEGVGLIIFDEFHERSLHADLGLALALQSQALLRPDLKILIMSATLEAEPVCRLLGDAPLLECPGTVFPVETFHMSKPSSTSLESFTAETVEKVLHTSEGDLLVFLPGAREIHRTERELASKHLPAHVKVIPLYGSMKLEQQDEAIRPSASGSRKVVLATSIAESSLTIAGITVVIDSGLSRESVFSARTGMSRLTTVKVSKASADQRRGRAGRLQPGVCYRLWSAQEQAALPDASRPEIAAADLAPLALELAAWGVREPAELAWLDAPPEAAYRQATGLLHQLGCLDEAADGTTGSITAHGREVSALGTHPRLGHMLLRATALGLAPTASRLAALLQERDPFRAHGGTDLRPRLDALREAAYARSTHSLLRAADDTVIRRIVQESRQLLAKLPTAAAAQDEPDGSAACGLLLAFAYPDRIAQGRGDGRFLLSGGRGARLGQVEWMSRSSYLVAAEVDDEGADGAIQLAAPIELQELVEHCSEMLLEQANVYWDSSASAVRARKVLRLGSLVLKETSYERPPAEEVAAALMQGVRERGLKLLSWNRQTLQLQARLIFMHFSAPEDWPDCTESALLDSLEAWLLPFAIGAKNVSDLQRLDSAALLLGRLDWEQRQQLDQEAPTHIRVPSGSRIPVDYSNPEAPALAVRLQELFGMGDTPRIGRGRVPIVLHLLSPAQRPVQVTSDLSSFWSEAYFEVKKDLKGRYPKHYWPDDPLEAVATNRAKPKR
>NZ_CP015423.1|WP_061830310.1|5129821_5130409_+|general-stress-protein
MANNLNDYNEKKIVGVFDTEQEASRAIGQLQSKGIPSSEISVITRDRDDLRAISEETGTKAPEGVATGAATGGVVGGVAGLLAGIGALAIPGIGPILAAGPIAATLTGAAVGAGAGGLVGGLVGLGIPEDDARQYETYVDQGKILVLVDSADHHRDVYDIFRTNRSLNADRYRTYDDTVADTPRTDVYTDTRRNL
>NZ_CP015423.1|WP_061830311.1|5130679_5131852_+|acyltransferase
MSQKERISEVALLRGLAFAAVVLQHSVAHYAVAQGARIQDGVLMTLLLLCSKFAVPVFVFITGMVLFYNYDGALKYGTFLRKRFMDIIVPYIIWSLLYELGNQLAQSGGYIHPLDFFQKLLNGKSSYHLWYIVMIIQCYVLFPVFRYAVRHLSALLPSKWRPAALAGFGVLYILLMFAVGPVYQAMDKLQLPVITSWFTLYADRNVIYFFFYFVLGAAAGMNVKRWNAWVTKAQMIYWPLFIVITGYLLYEMIGQFQTPRGTVLSFNYLSLLRPVMAVYCVASIFVAYRVATWIAHKGGRAASMLTAIGTLSYGAYLMHAFMLRVTYYFDERLFADWSHVLRTLASFVLCMIFSVAGTWLLARLPLGKWIVGLRVRPRPTGGPPALQKQA
>NZ_CP015423.1|WP_069291752.1|5131994_5132639_+|CatB-related-O-acetyltransferase
MSGPDIRSVFPMKNIRSLCFLNNVVVNPYIEIGDYTYYDDDDNPLDFEKNVLYHFDFIGDKLKIGKFCAIAAKAKFIMNGANHNTNAFTTFPFGAFGGDWEVGVPNLSGGYKGDTVVGNDVWIGYNASIMPGVQIGDGAIIASNAVVTKDVLPYSIVGGNPAKLIRYRFDEETIAMLQTLKWWDWDIQKITEYIPVLTSNDTEALKQLIQSSQS

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Crispr_ID: NZ_CP015423_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP015423_3

5121561-5122401

Orphan

NA:I-C

Consensus_repeat	Method
GTCGCACTCCATGT-GAGTGCGTGGATTGAAAT	PILER-CR
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCACTCCATGNTGAGTGCGTGGATTGAAAT	CRT

12 spacers

The CRISPR arrays of NZ_CP015423_3

>merge|NZ_CP015423|3|5121561-5122401|PILER-CR,CRISPRCasFinder,CRT
GTCGCACTCCATGTGAGTGCGTGGATTGAAATACTTGACAGGCCAAGCAGTAGGGGCGCGTGTTCGAGTCGCACTCCATGTGAGTGCGTGGATTGAAATAAGACGCAACAAAGCTAAACGCTATTGAACAGGAAGTCGCACTCCATGTGAGTGCGTGGATTGAAATATTTTTCTTGTGCATCGTTTTATTTCTCCTTGATGTCGCACTCCATGTGAGTGCGTGGATTGAAATGGATCCGTTATCGACGCCAACGGCGCATGGCTGACGTCGCACTCCATGTGAGTGCGTGGATTGAAATTTCCAGCAGGGCATCTTTAATGCCACTAATACTGTCGCACTCCATGTGAGTGCGTGGATTGAAATATATAAGACCTCCTAGTAGAAAAGCCCACCTTTTAGTCGCACTCCATGTGAGTGCGTGGATTGAAATTGTATAGACCGTGTGCGGTGCGAACACATAGTAAGGGTCGCACTCCATGTGAGTGCGTGGATTGAAATCTTGGATGATCGCATTTACAGCCATACGGCGAACGCGCGTCGCACTCCATGTGAGTGCGTGGATTGAAATAATATCTTAGGCAATTCCTCGCACAATTCAGGACAGGTCGCACTCCATGTGAGTGCGTGGATTGAAATCGCAAAATGAAAACGCGAGAGCAACAAGCAAAAATCGTCGCACTCCATGTGAGTGCGTGGATTGAAATGTCATGAGTCTAGCCGGGGTTGTCATAAGTGTAAGTCGCACTCTGTATGGAGTGCGTGGATTGATATTATCTTGCCGTTACTATTTGTGTAGCAGAGGTGCTATGTCGCATTCCATGTGAGTGCGTGGATGGTATG

>NZ_CP015423|3|3|5121561-5122197|PILER-CR
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ACTTGACAGGCCAAGCAGTAGGGGCGCGTGTTCGA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	AAGACGCAACAAAGCTAAACGCTATTGAACAGGAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ATTTTTCTTGTGCATCGTTTTATTTCTCCTTGAT
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	GGATCCGTTATCGACGCCAACGGCGCATGGCTGAC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TTCCAGCAGGGCATCTTTAATGCCACTAATACT
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ATATAAGACCTCCTAGTAGAAAAGCCCACCTTTTA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TGTATAGACCGTGTGCGGTGCGAACACATAGTAAGG
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	CTTGGATGATCGCATTTACAGCCATACGGCGAACGCGC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	AATATCTTAGGCAATTCCTCGCACAATTCAGGACAG
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT

>NZ_CP015423|3|3|5121561-5122265|CRISPRCasFinder
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ACTTGACAGGCCAAGCAGTAGGGGCGCGTGTTCGA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	AAGACGCAACAAAGCTAAACGCTATTGAACAGGAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ATTTTTCTTGTGCATCGTTTTATTTCTCCTTGAT
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	GGATCCGTTATCGACGCCAACGGCGCATGGCTGAC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TTCCAGCAGGGCATCTTTAATGCCACTAATACT
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ATATAAGACCTCCTAGTAGAAAAGCCCACCTTTTA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TGTATAGACCGTGTGCGGTGCGAACACATAGTAAGG
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	CTTGGATGATCGCATTTACAGCCATACGGCGAACGCGC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	AATATCTTAGGCAATTCCTCGCACAATTCAGGACAG
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	CGCAAAATGAAAACGCGAGAGCAACAAGCAAAAATC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT

>NZ_CP015423|3|3|5121561-5122401|CRT
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ACTTGACAGGCCAAGCAGTAGGGGCGCGTGTTCGA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	AAGACGCAACAAAGCTAAACGCTATTGAACAGGAA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ATTTTTCTTGTGCATCGTTTTATTTCTCCTTGAT
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	GGATCCGTTATCGACGCCAACGGCGCATGGCTGAC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TTCCAGCAGGGCATCTTTAATGCCACTAATACT
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	ATATAAGACCTCCTAGTAGAAAAGCCCACCTTTTA
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	TGTATAGACCGTGTGCGGTGCGAACACATAGTAAGG
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	CTTGGATGATCGCATTTACAGCCATACGGCGAACGCGC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	AATATCTTAGGCAATTCCTCGCACAATTCAGGACAG
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	CGCAAAATGAAAACGCGAGAGCAACAAGCAAAAATC
GTCGCACTCCATGTGAGTGCGTGGATTGAAAT	GTCATGAGTCTAGCCGGGGTTGTCATAAGTGTAAG
TCGCACTCTGTATGGAGTGCGTGGATTGATAT	TATCTTGCCGTTACTATTTGTGTAGCAGAGGTGCTAT
GTCGCATTCCATGTGAGTGCGTGGATGGTATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP015423.1\|WP_061830310.1\|5129821_5130409_+\|general-stress-protein	unknown	unknown	gnl\|CDD\|378584
NZ_CP015423.1\|WP_061829391.1\|5123072_5124467_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NZ_CP015423.1\|WP_061829393.1\|5117741_5118926_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|181082
NZ_CP015423.1\|WP_061829403.1\|5112726_5113536_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235546
NZ_CP015423.1\|WP_061829395.1\|5115217_5116702_+\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NZ_CP015423.1\|WP_061830311.1\|5130679_5131852_+\|acyltransferase	unknown	unknown	gnl\|CDD\|376607
NZ_CP015423.1\|WP_069291751.1\|5127174_5129703_+\|ATP-dependent-helicase-HrpB	unknown	unknown	gnl\|CDD\|273901
NZ_CP015423.1\|WP_155765263.1\|5114029_5114176_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015423.1\|WP_061829394.1\|5116810_5117740_+\|D-alanine--D-alanine-ligase	unknown	unknown	gnl\|CDD\|234948
NZ_CP015423.1\|WP_013309990.1\|5108254_5108530_+\|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl\|CDD\|274862
NZ_CP015423.1\|WP_061829457.1\|5125104_5125299_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP015423.1\|WP_061829458.1\|5107468_5108005_+\|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl\|CDD\|274862
NZ_CP015423.1\|WP_013309993.1\|5111626_5112463_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238083
NZ_CP015423.1\|WP_069291752.1\|5131994_5132639_+\|CatB-related-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100040
NZ_CP015423.1\|WP_013309992.1\|5110861_5111614_+\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|238119
NZ_CP015423.1\|WP_061829389.1\|5125862_5126858_-\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	unknown	unknown	gnl\|CDD\|235573
NZ_CP015423.1\|WP_061829404.1\|5108731_5110777_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236545
NZ_CP015423.1\|WP_081330748.1\|5124831_5124999_+\|aspartyl-phosphate-phosphatase-Spo0E-family-protein	unknown	unknown	gnl\|CDD\|378175
NZ_CP015423.1\|WP_061829390.1\|5125423_5125798_+\|DUF1992-domain-containing-protein	unknown	unknown	gnl\|CDD\|182303
NZ_CP015423.1\|WP_061829392.1\|5122557_5122740_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP015423.1\|WP_061829391.1\|5123072_5124467_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	2.60592e-05
NZ_CP015423.1\|WP_061829393.1\|5117741_5118926_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|181082	PRK07682, PRK07682, aminotransferase.	0
NZ_CP015423.1\|WP_061829403.1\|5112726_5113536_+\|SDR-family-oxidoreductase	gnl\|CDD\|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	1.58759e-90
NZ_CP015423.1\|WP_061829395.1\|5115217_5116702_+\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	6.30456e-125
NZ_CP015423.1\|WP_069291751.1\|5127174_5129703_+\|ATP-dependent-helicase-HrpB	gnl\|CDD\|273901	TIGR01970, ATP-dependent_RNA_helicase_HrpB, ATP-dependent helicase HrpB. This model represents HrpB, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria, but also in a few species of other lineages. The member from Rhizobium meliloti has been designated HelO. HrpB is typically about 800 residues in length, while its paralog HrpA (TIGR01967), also uncharacterized, is about 1300 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP015423.1\|WP_061830311.1\|5130679_5131852_+\|acyltransferase	gnl\|CDD\|376607	pfam01757, Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes. This domain is found in many as yet uncharacterized C. elegans proteins and it is approximately 300 amino acids long.	2.32348e-17
NZ_CP015423.1\|WP_061829394.1\|5116810_5117740_+\|D-alanine--D-alanine-ligase	gnl\|CDD\|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	1.62528e-143
NZ_CP015423.1\|WP_013309990.1\|5108254_5108530_+\|WXG100-family-type-VII-secretion-target	gnl\|CDD\|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	4.19531e-14
NZ_CP015423.1\|WP_061829458.1\|5107468_5108005_+\|WXG100-family-type-VII-secretion-target	gnl\|CDD\|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	4.44504e-06
NZ_CP015423.1\|WP_013309993.1\|5111626_5112463_+\|hypothetical-protein	gnl\|CDD\|238083	cd00143, PP2Cc, Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence similarity.	0.00422194
NZ_CP015423.1\|WP_069291752.1\|5131994_5132639_+\|CatB-related-O-acetyltransferase	gnl\|CDD\|100040	cd03349, LbH_XAT, Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. Members of this class of enzymes include Enterococcus faecium streptogramin A acetyltransferase and Pseudomonas aeruginosa chloramphenicol acetyltransferase. They contain repeated copies of a six-residue hexapeptide repeat sequence motif (X-[STAV]-X-[LIV]-[GAED]-X) and adopt a left-handed parallel beta helix (LbH) structure. The active enzyme is a trimer with CoA and substrate binding sites at the interface of two separate LbH subunits. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients.	5.45542e-75
NZ_CP015423.1\|WP_013309992.1\|5110861_5111614_+\|VWA-domain-containing-protein	gnl\|CDD\|238119	cd00198, vWFA, Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains.	8.50689e-08
NZ_CP015423.1\|WP_061829389.1\|5125862_5126858_-\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	gnl\|CDD\|235573	PRK05710, PRK05710, tRNA glutamyl-Q(34) synthetase GluQRS.	2.6473e-114
NZ_CP015423.1\|WP_061829404.1\|5108731_5110777_+\|hypothetical-protein	gnl\|CDD\|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	2.7195e-12
NZ_CP015423.1\|WP_081330748.1\|5124831_5124999_+\|aspartyl-phosphate-phosphatase-Spo0E-family-protein	gnl\|CDD\|378175	pfam09388, SpoOE-like, Spo0E like sporulation regulatory protein. Spore formation is an extreme response to starvation and can also be a component of disease transmission. Sporulation is controlled by an expanded two-component system where starvation signals result in sensor kinase activation and phosphorylation of the master sporulation response regulator Spo0A. Phosphatases such as Spo0E dephosphorylate Spo0A thereby inhibiting sporulation. This is a family of Spo0E-like phosphatases. The structure of a Bacillus anthracis member of this family has revealed an anti-parallel alpha-helical structure.	4.856e-08
NZ_CP015423.1\|WP_061829390.1\|5125423_5125798_+\|DUF1992-domain-containing-protein	gnl\|CDD\|182303	PRK10203, PRK10203, hypothetical protein; Provisional.	1.02521e-32
NZ_CP015423.1\|WP_061830310.1\|5129821_5130409_+\|general-stress-protein	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	1.04325e-12

>NZ_CP015423.1|WP_061829393.1|5117741_5118926_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MFSEMGTGRFVSSRVRDIRPSGIRAFFDLNAAGGGTIALGVGEPDFVTPDKVREACIQALREGQTKYTSNAGLMELREEISAYFSGSFALSYDPEQEMIVTVGSSEAVDLALRAVIDPGDEVLIPAPSYIAYEPITHLHGGKIVEVAATAEEQFKLTPQALQAAITPHSKVLMINYPCNPTGTVMTEQDWLPITELIIKHNLVVISDEVYAELTYGRKHVSIASLPGMKERTIVISGFSKAFAMTGWRVGYACGPHELIAGMLKIHQYTAMCAPTIAQIAALESLRHGLAAKDEMMASYNERRKLFVAGLNAIGLACHEPEGAFYAFPSITSTGMSSEQFALRMLKEAKVAVVPGHVFGSGGEGFIRCSYAASLVDLEKALKRMGRFMQVMQPV
>NZ_CP015423.1|WP_061829394.1|5116810_5117740_+|D-alanine--D-alanine-ligase
MKIGVIMGGISSEREISLQTGQEMINHLDRSRYEVVPMVIEQRADLIAQVQQAGIDIALLALHGQYGEDGTVQGALETLGIPYTGSGVLASSLCMNKQLSKMLLKAAGVHTPSGLYWQGMDDYDPQVVEHLGYPVIVKPNMGGSSIGIQLVQNEKELLPAVQEACSLDQAILIEPYYEGTEITCSIVDGEVLPIISISSARSKWFDYKAKYEVGGAEEKVIELPPVIEQRVREAALSSYRLLQCKVYARIDMILCQDRPYVLEVNTLPGMTANSLLPKSAAAAGITFTQLLDQIIASSLHERKQEWRMA
>NZ_CP015423.1|WP_061829395.1|5115217_5116702_+|PLP-dependent-aminotransferase-family-protein
MFQDFKLVSDRPVSIQVKEYVNRLIIKGALQADQKLPSTREMSVLLKVSRNTVIAAYEGLEDDGFTYAIPGKGSYVAAMVGQSAVDNGGSDGSATWEIDWKARMNEYAVLAVDLDMMKQGIRAQKGTISFTSIAPDEQLFDLGDVRRAFMDRMAIEGQVLLNYGYAKGYKPLIDYLMHYMENKGVDIIGKDMLITGGFTEGFDIVLSALRPSARRGAAICENPTHHTAIKNLKLQGFEITGIPMECDGIDVERLEEVLQTNSFDLAYLTPSYHNPTGIVMSPAKRSAVMKLMMSYQIPVIEDGFNEELRYSGAHIAPLIATAGQGNGVIYIGSFSKVLFPGLRVGWVLGDRALIDTLESIKRARTIHTSTIDQSILYQYMLNGNFDKHVKKARTEYKRKYELTKTCCEAHLPEAQVSGDGGLHLFLTFPTGVNTRQLLEACTEQGVIFTPGDKFFIQEGEGTNTLRLGFSRVTDENIERGIQIIGKQTRKFLKA
>NZ_CP015423.1|WP_155765263.1|5114029_5114176_+|hypothetical-protein
MSIDLAPTAKIPVVALYMSAWIEMLRNRSNASVGQAVALYMSAWIEIH
>NZ_CP015423.1|WP_061829403.1|5112726_5113536_+|SDR-family-oxidoreductase
MSYTYAGGARFEGKTALITGAGSGIGKATAIQMAREGANVALFDVSNERISETEREINAIREGSARAFDVDIADPVRVEKAVLEAVELFGGLHIIFANAGINGVVGPIEDLSIEDWRQTLSTNLDGTFLTVKYTIPHLKKNGGGSIIITSSINGNQRFTSFGMSAYSTSKAGQTGFAKMAALELAKFRIRVNVIYPGAISTNIDETTEKSEGLKQITIPVKFPEGGQPLADGPGQPEQVADLVTFLASDHSRHITGAQIVIDGAESLLF
>NZ_CP015423.1|WP_013309993.1|5111626_5112463_+|hypothetical-protein
MNPLLSLLPASKKKGMNARLTQQFAYISSQTGDQPLSSHHSRFMCRYGYGRSAESASMGESGQDFAAVRIHKSVCCFVLCDGVGLSYRGDFAARYLGSSLLDWMERGQDLSADQLRVYLERLAGTAAEELDRQPLDHESGLMRSVLEDKRRQGSQSMYICGKIELPKRGSRGRLRLAWQGDSRLRLWNGAEEISELFDHTFSTAERWSTSRGPIGGKPHWYERSIPADMPMRLQVYTDGLSDLDPIREPVPDEQIQVLLDASHTGGLDDDAAFIELQW
>NZ_CP015423.1|WP_013309992.1|5110861_5111614_+|VWA-domain-containing-protein
MNYTIQASQRTPALIIYLIDISASMNMLMEGRRRIDVVYEAISLAIRQMVFRSTKGNRLTARYRIAILAYSDDVYDLLNGVKGIDEIAAIGSLPDLTPKRFSDSAKAFLQAERILQAELPGMQDCPAPLVCHMTDGVSTGDDPEPIAKRIMSMSVPDGNVLVENIFLSDRLLETPIQDPRRWKGLTHNTPLQDEHAVKLRDMSSVLPESYREMLFEADYQLGEGAIMMLPGTCAELVSIGFQMSAATPVR
>NZ_CP015423.1|WP_061829404.1|5108731_5110777_+|hypothetical-protein
MSFQPNPGDELIINGTAYVVGRHPAAPGLAYAQAGRQGIVYQLNAKNGAPHEAKALKVFFPKFRIPAMVYQSEHMEAYGDIPGLQVCKRDVLTPERNGSLIAEQPDLLYAVLMPWVHGMTWFDCLTDQRQLEASDSLALARALAGIGSAMEQKGLAHCDLSAPNVMLPFFSEVELPQGTSAVELVDVEQMYSTKMDRPDALLAGSPGYAAHRTVHSGLWSAYADRFAGAIIIGEMLGWSDRVVVDKAWGESYFDQHEMQTPCERYFILRKSLESRWGSKVVELFSRAWDSQDLSSCPTFGEWLVVLNAVTEQEIPVEAIEPEPAATETIESAAVGGLASEAAPSLSAPAPLKAEQAALLNQAALEQGERGVTDKLFRQARDLEQQNKPAAALEVYRSLYHFVEDGSPLHVEVSAAITGLEEQLNPKTPEQPEKSKAWYRSKAFIVTTAAAVVVLAAGIPAVNILADQSNQRQIEAAKQEEAAKAAKAAEEKLAAEQEAAQKLLTEKQRQEAEQQTKQQALAAQKQQEEQKKQQALIAQQVKYEAYLAQKEQNKQAAAKLAKQKAYDQQAKYEKYLALKKEQEARAAQEEAARKAAAEAEQKQKESMHARNKENVLQLISLYNKAYASQEGGSAAKAKSFAKRFRTLYDSNPSYYRSVGEVGYRASSIYNFLGDTNFRLPKI
>NZ_CP015423.1|WP_013309990.1|5108254_5108530_+|WXG100-family-type-VII-secretion-target
MAGRILITPEQVDQVANQFKQSGEQSQQIVSSLTQSISGMEGQWEGMTKQRFFQEFQEASKQMQAFVTTLNSISQELTAIANKFRTVDQTK
>NZ_CP015423.1|WP_061829458.1|5107468_5108005_+|WXG100-family-type-VII-secretion-target
MRIRVEPDVLRGLSGQLQHAAEQIQQLTAGLEQALQSLDWDVSAREAILNHWMQAKRMSEQIHAYLHTSGTQLNRKAEQFQSVDHNYQTILSFASQPLGRPVTMLDWSNQQSPSILPGQASEGGSLISNPQSVVHAIAGVQSSDIETLHQDILMQASSSSPQDWYFTDPSTARDQPVA
>NZ_CP015423.1|WP_061829392.1|5122557_5122740_+|hypothetical-protein
MRISMSKFLKRYAAILLGYAICIGLFYALGYKMSAMGIYAILTGIVTGEIINFVLSKREK
>NZ_CP015423.1|WP_061829391.1|5123072_5124467_+|helix-turn-helix-transcriptional-regulator
MKHTPTISAEFEDYLKQNDMTLSQFAEYSGVHQRTLSHWITQHRPVSIQQLDRITVAMDLPEGYFYDLYIENYIIDLSPNFRRIEPLLYRCAELDKLDAIRRMVGHIMDNPLYATRLFDVAEALFEQGRHAAALPLYENVAEVEKYQHSERLATCQYRIFSIQVGDDQSRNLKAATLFEPFVERLDEIDQLDALKDLANVYRSLRLWDRLDVTARKMRDKAEIQYTLEHQQKKRKSAEIEKRLSRPLFVYITYADLLCASVCEAQGDYQQALQYTYAYVNLDWVKETDEDTLHWIKLFQNWALCNTYVNKLLSGDISVLPDYVEYISVSSNTTKEMVTQLLNIMMAANRFQVDVDEVLKQFETEIDSITQQQPSADMYTHRVVPEQLTRFKYELAKYYLNKGNYSYGFKNLLDVLSKSLVINKEAFFISCIRLFEQFKQFADFRLCTKYESLVREGRKERLFYY
>NZ_CP015423.1|WP_081330748.1|5124831_5124999_+|aspartyl-phosphate-phosphatase-Spo0E-family-protein
MLMNPGVTLLRVERARKRLYQIQKKYGFLTHPKVIEQSMKLDELLNQYQTCKMKS
>NZ_CP015423.1|WP_061829457.1|5125104_5125299_+|hypothetical-protein
MNKRNPVTPFGWKIKQKLVEIQMDQRTFCDTYHIPASRLSNLIHGTRKAKKYRVQVSQLLGIEE
>NZ_CP015423.1|WP_061829390.1|5125423_5125798_+|DUF1992-domain-containing-protein
MGMFSRMAEQKIAEAMAKGEFDHLPGEGKPLVIEDLSHVPEELRMSYKLLKNAGILPEELQLQKECVQLRDLLHACHEAGERERISRRLTEKSLRLRMLLEERGLNTSSVFYEYESAMRKRLEE
>NZ_CP015423.1|WP_061829389.1|5125862_5126858_-|tRNA-glutamyl-Q(34)-synthetase-GluQRS
MELQAQPIRGRFAPTPSGWIHLGNARTALLSWLHVRSLGGTYILRMEDIDMTRARSQLAQGIMEDLRWIGLNWDEGPDVGGPYGSYTQSQRLERYQSALEKLQRQDLLYPCFCSRADILAAAHAPHGLSGEGPAYSGACRNLSFQDVVAKAQYKLPSLRFKVPQYPDAVISFHDQVAGHVAFGAAEGGDFIVKRADGMFSYQLAVVIDDADMHMTDVLRGYDLLDSTPRQLLLYQAFGLQPPRFAHVPLVLGPDGRRLAKRHGGVALRAMRRQGVTPEAVIGWLAYFSGLLDSPEPVKAEDLIDDFHLDKLPKEPVILTKQCLTRLSALQR
>NZ_CP015423.1|WP_069291751.1|5127174_5129703_+|ATP-dependent-helicase-HrpB
MTDKQLPIMQVIPELKHTLQSHSAAVLIAQPGAGKTTVTPLELLHEPWLAGQKMMMLEPRRLAARAAAAQMAKALGEPTGKTVGYRVRMDTKVGPNTRIEVVTEGVLTRMLQHDQALEGVGLIIFDEFHERSLHADLGLALALQSQALLRPDLKILIMSATLEAEPVCRLLGDAPLLECPGTVFPVETFHMSKPSSTSLESFTAETVEKVLHTSEGDLLVFLPGAREIHRTERELASKHLPAHVKVIPLYGSMKLEQQDEAIRPSASGSRKVVLATSIAESSLTIAGITVVIDSGLSRESVFSARTGMSRLTTVKVSKASADQRRGRAGRLQPGVCYRLWSAQEQAALPDASRPEIAAADLAPLALELAAWGVREPAELAWLDAPPEAAYRQATGLLHQLGCLDEAADGTTGSITAHGREVSALGTHPRLGHMLLRATALGLAPTASRLAALLQERDPFRAHGGTDLRPRLDALREAAYARSTHSLLRAADDTVIRRIVQESRQLLAKLPTAAAAQDEPDGSAACGLLLAFAYPDRIAQGRGDGRFLLSGGRGARLGQVEWMSRSSYLVAAEVDDEGADGAIQLAAPIELQELVEHCSEMLLEQANVYWDSSASAVRARKVLRLGSLVLKETSYERPPAEEVAAALMQGVRERGLKLLSWNRQTLQLQARLIFMHFSAPEDWPDCTESALLDSLEAWLLPFAIGAKNVSDLQRLDSAALLLGRLDWEQRQQLDQEAPTHIRVPSGSRIPVDYSNPEAPALAVRLQELFGMGDTPRIGRGRVPIVLHLLSPAQRPVQVTSDLSSFWSEAYFEVKKDLKGRYPKHYWPDDPLEAVATNRAKPKR
>NZ_CP015423.1|WP_061830310.1|5129821_5130409_+|general-stress-protein
MANNLNDYNEKKIVGVFDTEQEASRAIGQLQSKGIPSSEISVITRDRDDLRAISEETGTKAPEGVATGAATGGVVGGVAGLLAGIGALAIPGIGPILAAGPIAATLTGAAVGAGAGGLVGGLVGLGIPEDDARQYETYVDQGKILVLVDSADHHRDVYDIFRTNRSLNADRYRTYDDTVADTPRTDVYTDTRRNL
>NZ_CP015423.1|WP_061830311.1|5130679_5131852_+|acyltransferase
MSQKERISEVALLRGLAFAAVVLQHSVAHYAVAQGARIQDGVLMTLLLLCSKFAVPVFVFITGMVLFYNYDGALKYGTFLRKRFMDIIVPYIIWSLLYELGNQLAQSGGYIHPLDFFQKLLNGKSSYHLWYIVMIIQCYVLFPVFRYAVRHLSALLPSKWRPAALAGFGVLYILLMFAVGPVYQAMDKLQLPVITSWFTLYADRNVIYFFFYFVLGAAAGMNVKRWNAWVTKAQMIYWPLFIVITGYLLYEMIGQFQTPRGTVLSFNYLSLLRPVMAVYCVASIFVAYRVATWIAHKGGRAASMLTAIGTLSYGAYLMHAFMLRVTYYFDERLFADWSHVLRTLASFVLCMIFSVAGTWLLARLPLGKWIVGLRVRPRPTGGPPALQKQA
>NZ_CP015423.1|WP_069291752.1|5131994_5132639_+|CatB-related-O-acetyltransferase
MSGPDIRSVFPMKNIRSLCFLNNVVVNPYIEIGDYTYYDDDDNPLDFEKNVLYHFDFIGDKLKIGKFCAIAAKAKFIMNGANHNTNAFTTFPFGAFGGDWEVGVPNLSGGYKGDTVVGNDVWIGYNASIMPGVQIGDGAIIASNAVVTKDVLPYSIVGGNPAKLIRYRFDEETIAMLQTLKWWDWDIQKITEYIPVLTSNDTEALKQLIQSSQS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP015423_2	2.1\|5119442\|35\|NZ_CP015423\|PILER-CR,CRISPRCasFinder,CRT	5119442-5119476	35	NZ_CP015423.1	3769572-3769606	0	1.0
NZ_CP015423_3	3.1\|5121593\|35\|NZ_CP015423\|PILER-CR,CRISPRCasFinder,CRT	5121593-5121627	35	NZ_CP015423.1	4115067-4115101	0	1.0

1. spacer 2.1|5119442|35|NZ_CP015423|PILER-CR,CRISPRCasFinder,CRT matches to position: 3769572-3769606, mismatch: 0, identity: 1.0

tttgttcctcgctcagcatgcggatcaggtgtatg	CRISPR spacer
tttgttcctcgctcagcatgcggatcaggtgtatg	Protospacer
***********************************

2. spacer 3.1|5121593|35|NZ_CP015423|PILER-CR,CRISPRCasFinder,CRT matches to position: 4115067-4115101, mismatch: 0, identity: 1.0

acttgacaggccaagcagtaggggcgcgtgttcga	CRISPR spacer
acttgacaggccaagcagtaggggcgcgtgttcga	Protospacer
***********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP015423_1	1.26\|5114507\|38\|NZ_CP015423\|CRT	5114507-5114544	38	NZ_CP040830	Paenibacillus polymyxa strain ZF129 plasmid pAP1, complete sequence	23995-24032	6	0.842
NZ_CP015423_3	3.5\|5121860\|33\|NZ_CP015423\|PILER-CR,CRISPRCasFinder,CRT	5121860-5121892	33	NC_008739	Marinobacter hydrocarbonoclasticus VT8 plasmid pMAQU02, complete sequence	198883-198915	6	0.818
NZ_CP015423_1	1.11\|5114515\|36\|NZ_CP015423\|PILER-CR	5114515-5114550	36	NZ_CP040830	Paenibacillus polymyxa strain ZF129 plasmid pAP1, complete sequence	23997-24032	7	0.806
NZ_CP015423_1	1.9\|5114377\|34\|NZ_CP015423\|PILER-CR	5114377-5114410	34	NC_048847	Alteromonas phage vB_AmeM_PT11-V22, complete genome	6071-6104	9	0.735
NZ_CP015423_1	1.35\|5114372\|34\|NZ_CP015423\|CRISPRCasFinder	5114372-5114405	34	NC_048847	Alteromonas phage vB_AmeM_PT11-V22, complete genome	6071-6104	9	0.735
NZ_CP015423_1	1.12\|5114584\|38\|NZ_CP015423\|PILER-CR	5114584-5114621	38	NC_008208	Aeromonas phage 25, complete genome	11370-11407	10	0.737
NZ_CP015423_1	1.12\|5114584\|38\|NZ_CP015423\|PILER-CR	5114584-5114621	38	DQ529280	Aeromonas salmonicida bacteriophage 25, complete genome	11370-11407	10	0.737
NZ_CP015423_1	1.24\|5114371\|35\|NZ_CP015423\|CRT	5114371-5114405	35	NC_048847	Alteromonas phage vB_AmeM_PT11-V22, complete genome	6070-6104	10	0.714
NZ_CP015423_2	2.1\|5119442\|35\|NZ_CP015423\|PILER-CR,CRISPRCasFinder,CRT	5119442-5119476	35	NC_022044	Paracoccus aminophilus JCM 7686 plasmid pAMI6, complete sequence	120-154	10	0.714
NZ_CP015423_3	3.3\|5121727\|34\|NZ_CP015423\|PILER-CR,CRISPRCasFinder,CRT	5121727-5121760	34	MT446416	UNVERIFIED: Escherichia virus TH47, complete genome	297881-297914	10	0.706

1. spacer 1.26|5114507|38|NZ_CP015423|CRT matches to NZ_CP040830 (Paenibacillus polymyxa strain ZF129 plasmid pAP1, complete sequence) position: , mismatch: 6, identity: 0.842

-attgcattagatgagtgatcacgttcggccttactata	CRISPR spacer
gactgt-tcagatgagcgatcacgttcggctttactata	Protospacer
 *.**. *.*******.*************.********

2. spacer 3.5|5121860|33|NZ_CP015423|PILER-CR,CRISPRCasFinder,CRT matches to NC_008739 (Marinobacter hydrocarbonoclasticus VT8 plasmid pMAQU02, complete sequence) position: , mismatch: 6, identity: 0.818

ttccagcagggcatctttaatgccactaatact-	CRISPR spacer
ttccagcacgacatctttaatgcc-ctgatccac	Protospacer
******** *.************* **.** *

3. spacer 1.11|5114515|36|NZ_CP015423|PILER-CR matches to NZ_CP040830 (Paenibacillus polymyxa strain ZF129 plasmid pAP1, complete sequence) position: , mismatch: 7, identity: 0.806

tgcattagatgagtgatcacgttcggccttactata	CRISPR spacer
ctgttcagatgagcgatcacgttcggctttactata	Protospacer
.   *.*******.*************.********

4. spacer 1.9|5114377|34|NZ_CP015423|PILER-CR matches to NC_048847 (Alteromonas phage vB_AmeM_PT11-V22, complete genome) position: , mismatch: 9, identity: 0.735

cattcttaattgtgttaactctaaaaacgtctcc	CRISPR spacer
cagtcttaatagtgttaactctaaaggaggggca	Protospacer
** ******* **************.. *   *

5. spacer 1.35|5114372|34|NZ_CP015423|CRISPRCasFinder matches to NC_048847 (Alteromonas phage vB_AmeM_PT11-V22, complete genome) position: , mismatch: 9, identity: 0.735

cattcttaattgtgttaactctaaaaacgtctcc	CRISPR spacer
cagtcttaatagtgttaactctaaaggaggggca	Protospacer
** ******* **************.. *   *

6. spacer 1.12|5114584|38|NZ_CP015423|PILER-CR matches to NC_008208 (Aeromonas phage 25, complete genome) position: , mismatch: 10, identity: 0.737

agacgtaagccaccaagcaaagaaacaattctcccagg	CRISPR spacer
agcacctacgcaccaagcaaagaaagaattgtcccagc	Protospacer
**   . *  *************** **** ******

7. spacer 1.12|5114584|38|NZ_CP015423|PILER-CR matches to DQ529280 (Aeromonas salmonicida bacteriophage 25, complete genome) position: , mismatch: 10, identity: 0.737

agacgtaagccaccaagcaaagaaacaattctcccagg	CRISPR spacer
agcacctacgcaccaagcaaagaaagaattgtcccagc	Protospacer
**   . *  *************** **** ******

8. spacer 1.24|5114371|35|NZ_CP015423|CRT matches to NC_048847 (Alteromonas phage vB_AmeM_PT11-V22, complete genome) position: , mismatch: 10, identity: 0.714

tcattcttaattgtgttaactctaaaaacgtctcc	CRISPR spacer
gcagtcttaatagtgttaactctaaaggaggggca	Protospacer
 ** ******* **************.. *   *

9. spacer 2.1|5119442|35|NZ_CP015423|PILER-CR,CRISPRCasFinder,CRT matches to NC_022044 (Paracoccus aminophilus JCM 7686 plasmid pAMI6, complete sequence) position: , mismatch: 10, identity: 0.714

tttgttcctcgctcagcatgcggatcaggtgtatg	CRISPR spacer
gcttttcctcgctcagcttgcggatgaggggctgc	Protospacer
 .* ************* ******* *** *.

10. spacer 3.3|5121727|34|NZ_CP015423|PILER-CR,CRISPRCasFinder,CRT matches to MT446416 (UNVERIFIED: Escherichia virus TH47, complete genome) position: , mismatch: 10, identity: 0.706

atttttcttgtgcatcgttttatttctccttgat	CRISPR spacer
tttcttcttgtgcatcgtttgatttaaaatataa	Protospacer
 **.**************** ****    *  *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

68537 : 76344

Bacillus_virus(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_081330659.1\|68537_69374_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.4e-18	34.7
WP_069289629.1\|69366_70209_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	6.3e-14	24.2
WP_069289630.1\|70175_71486_+	MATE family efflux transporter	NA	NA	NA	NA
WP_069289631.1\|71610_73068_-	catalase	A0A2K9L0T1	Tupanvirus	2.5e-114	42.8
WP_069289632.1\|73358_73961_-	adenylyl-sulfate kinase	NA	NA	NA	NA
WP_069289633.1\|74022_74922_-	TIGR02452 family protein	G3MBH6	Bacillus_virus	1.6e-55	44.6
WP_069289634.1\|74927_75410_-	NADAR family protein	A0A0S0N9W6	Pseudomonas_phage	5.2e-45	58.1
WP_061828302.1\|75438_76344_-	NUDIX hydrolase	G3MA14	Bacillus_virus	7.0e-35	34.3

DBSCAN-SWA_2

248238 : 272184

Paenibacillus_phage(33.33%)

capsid,holin,head,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_069289700.1\|248238_248580_-\|holin	phage holin	NA	NA	NA	NA
WP_081330664.1\|248582_249413_-	glycoside hydrolase family 25 protein	D0R7H8	Paenibacillus_phage	2.2e-67	60.2
WP_069289701.1\|249390_249894_-\|holin	phage holin family protein	D0R7H7	Paenibacillus_phage	6.8e-80	93.8
WP_069291989.1\|249868_250090_-	hypothetical protein	NA	NA	NA	NA
WP_081330665.1\|250130_250844_-	phage antirepressor KilAC domain-containing protein	A0A2D1GQ65	Lysinibacillus_phage	6.9e-54	52.1
WP_172828246.1\|251291_252383_+	tyrosinase family protein	NA	NA	NA	NA
WP_069289703.1\|253143_253788_-	antirepressor	A0A2H4JB17	uncultured_Caudovirales_phage	2.2e-43	47.5
WP_069289704.1\|253986_254193_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_069289705.1\|254291_254858_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_069289706.1\|255074_255671_-	2,' 3'-cyclic nucleotide 2'-phosphodiesterase	R9TPZ8	Paenibacillus_phage	4.0e-15	38.9
WP_069289707.1\|255735_257886_-\|tail	phage tail protein	A0A2H4JAC2	uncultured_Caudovirales_phage	2.4e-17	27.8
WP_069289708.1\|257894_258533_-	hypothetical protein	NA	NA	NA	NA
WP_069289709.1\|258549_259917_-	right-handed parallel beta-helix repeat-containing protein	NA	NA	NA	NA
WP_069289710.1\|259926_260337_-	hypothetical protein	H6BJ44	Methylophilales_phage	6.6e-25	41.6
WP_069289711.1\|260348_260903_-\|tail	phage tail family protein	NA	NA	NA	NA
WP_069289712.1\|260902_266371_-	transglycosylase	NA	NA	NA	NA
WP_172828247.1\|266398_266542_-	hypothetical protein	NA	NA	NA	NA
WP_014599920.1\|266672_267014_-	hypothetical protein	NA	NA	NA	NA
WP_061829308.1\|267073_267859_-	hypothetical protein	NA	NA	NA	NA
WP_069289713.1\|267905_268352_-	hypothetical protein	NA	NA	NA	NA
WP_069289714.1\|268362_268797_-	hypothetical protein	NA	NA	NA	NA
WP_069289715.1\|268793_269372_-	hypothetical protein	NA	NA	NA	NA
WP_069289716.1\|269368_269944_-	hypothetical protein	NA	NA	NA	NA
WP_069289717.1\|269943_270378_-	hypothetical protein	NA	NA	NA	NA
WP_069289718.1\|270367_270757_-	hypothetical protein	NA	NA	NA	NA
WP_069289719.1\|270774_271788_-\|capsid	major capsid protein	A0A1U9WQS4	Geobacillus_phage	1.1e-12	23.1
WP_025724057.1\|271803_272184_-\|head	head decoration protein	A0A139ZPE9	Marinitoga_camini_virus	8.0e-09	47.1

DBSCAN-SWA_3

289232 : 303550

Paenibacillus_phage(40.0%)

integrase

attL 294306:294319|attR 304900:304913

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_069289731.1\|289232_289523_-	hypothetical protein	A0A127AWG6	Bacillus_phage	7.0e-21	51.0
WP_069289732.1\|289695_289896_+	hypothetical protein	NA	NA	NA	NA
WP_069289733.1\|289982_290168_-	hypothetical protein	NA	NA	NA	NA
WP_069289734.1\|290197_290413_-	hypothetical protein	NA	NA	NA	NA
WP_069291991.1\|290442_291183_-	site-specific DNA-methyltransferase	A0A0E3IAX4	Synechococcus_phage	1.9e-78	56.6
WP_172828249.1\|291187_291358_-	hypothetical protein	NA	NA	NA	NA
WP_069289735.1\|291400_292072_-	HNH endonuclease	D0R7I8	Paenibacillus_phage	6.7e-91	92.9
WP_061829345.1\|292144_292327_-	hypothetical protein	NA	NA	NA	NA
WP_069289736.1\|292323_292512_-	hypothetical protein	NA	NA	NA	NA
WP_061829347.1\|292782_292992_+	helix-turn-helix transcriptional regulator	D0R7I7	Paenibacillus_phage	1.7e-16	100.0
WP_172828250.1\|293074_293251_-	hypothetical protein	D0R7I6	Paenibacillus_phage	2.0e-23	93.1
WP_172828251.1\|293247_293562_-	hypothetical protein	NA	NA	NA	NA
WP_069289737.1\|293512_294031_-	DUF1064 domain-containing protein	D0R7I5	Paenibacillus_phage	1.8e-88	98.8
WP_069289738.1\|294031_295150_-	DNA polymerase III subunit beta	D0R7I4	Paenibacillus_phage	2.2e-46	56.9
294306:294319	attL	NA	NA	NA	NA
WP_069289739.1\|295266_296223_-	primosomal protein DnaI	S5MU12	Brevibacillus_phage	1.1e-62	49.2
WP_069289740.1\|296227_297283_-	replication protein	S5M5Q5	Brevibacillus_phage	5.6e-44	34.2
WP_069289741.1\|297310_297709_-	hypothetical protein	A0A0K2CYI4	Paenibacillus_phage	6.4e-09	36.3
WP_069289742.1\|297732_298431_-	hypothetical protein	Q8W6Q8	Burkholderia_virus	2.2e-20	30.2
WP_069289743.1\|298491_298890_-	hypothetical protein	NA	NA	NA	NA
WP_069289744.1\|298880_299240_-	hypothetical protein	NA	NA	NA	NA
WP_069289745.1\|299345_299777_-	ORF6C domain-containing protein	NA	NA	NA	NA
WP_069289746.1\|299773_300895_-	ParB N-terminal domain-containing protein	A0A1D6Z271	Staphylococcus_phage	6.8e-40	45.0
WP_069289747.1\|301146_301413_-	group-specific protein	A0A1B1P7U4	Bacillus_phage	1.2e-24	59.3
WP_069289748.1\|301425_301638_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_069289749.1\|301868_302252_+	helix-turn-helix transcriptional regulator	O03970	Lactobacillus_phage	1.7e-14	31.7
WP_069289750.1\|302362_303550_+\|integrase	site-specific integrase	A0A0S2SXP1	Bacillus_phage	8.0e-55	59.7
304900:304913	attR	NA	NA	NA	NA

DBSCAN-SWA_4

492608 : 499944

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_061829258.1\|492608_493871_-	D-alanyl-D-alanine carboxypeptidase	A0A1P8VVG5	Erythrobacter_phage	3.9e-07	31.6
WP_061829233.1\|494088_494811_+	hypothetical protein	NA	NA	NA	NA
WP_061829234.1\|494903_495395_-	sporulation protein YtfJ	NA	NA	NA	NA
WP_061829235.1\|495561_496275_-	DUF2953 domain-containing protein	NA	NA	NA	NA
WP_061829236.1\|496442_497054_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	5.4e-15	32.8
WP_029517304.1\|497022_497817_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	3.7e-08	30.5
WP_061829237.1\|497990_498455_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	9.7e-41	59.9
WP_081112430.1\|498534_499218_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	2.3e-59	55.2
WP_039271010.1\|499278_499944_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	8.5e-38	39.5

DBSCAN-SWA_5

3711880 : 3723489

Mollivirus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013308794.1\|3711880_3713179_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	9.1e-20	33.1
WP_069291118.1\|3713886_3714768_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0M4JBD3	Mollivirus	3.7e-41	35.1
WP_013308797.1\|3714826_3715072_+	phosphoribosylformylglycinamidine synthase subunit PurS	A0A0E3FJ99	Synechococcus_phage	8.2e-07	37.7
WP_069291119.1\|3715076_3715766_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_069291120.1\|3715743_3717987_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.4e-164	42.4
WP_069291121.1\|3717971_3719453_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.8e-51	31.3
WP_155765243.1\|3719778_3720018_-	hypothetical protein	NA	NA	NA	NA
WP_061832069.1\|3720156_3721197_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.7e-69	45.5
WP_061832070.1\|3721196_3721811_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.6e-22	36.4
WP_061832071.1\|3721941_3723489_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	3.4e-74	52.0

DBSCAN-SWA_6

3793168 : 3802603

uncultured_Caudovirales_phage(25.0%)

integrase,terminase,coat,portal

attL 3781255:3781267|attR 3796853:3796865

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3781255:3781267	attL	NA	NA	NA	NA
WP_029515592.1\|3793168_3794437_+	DNA modification methylase	A0A1B0RXJ0	Streptococcus_phage	1.7e-132	54.4
WP_172828296.1\|3794455_3794614_+	hypothetical protein	NA	NA	NA	NA
WP_029515591.1\|3794678_3795422_+	hypothetical protein	A0A2H4JAE2	uncultured_Caudovirales_phage	4.4e-19	38.6
WP_029515590.1\|3795581_3796427_+\|integrase	tyrosine-type recombinase/integrase	A0A1B1IQT7	uncultured_Mediterranean_phage	1.3e-11	27.2
WP_029515589.1\|3796603_3798154_+\|terminase	phage terminase large subunit	A0A0N7AEF1	Bacillus_phage	7.7e-74	33.3
3796853:3796865	attR	NA	NA	NA	NA
WP_029515588.1\|3798359_3798893_+	cupin domain-containing protein	Q2I8C5	Bacillus_phage	2.7e-63	71.3
WP_069291143.1\|3799042_3800350_+\|portal	phage portal protein	A0A1V0DZW8	Clostridioides_phage	2.2e-53	31.4
WP_029515585.1\|3801127_3801745_+	DUF4355 domain-containing protein	A0A2H4J4P4	uncultured_Caudovirales_phage	1.2e-22	35.8
WP_029515584.1\|3801772_3802603_+\|coat	coat protein	A0A1L2JY55	Aeribacillus_phage	3.6e-78	52.9

DBSCAN-SWA_7

4132694 : 4151461

Bacillus_phage(46.67%)

plate,holin,portal,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_069291301.1\|4132694_4133120_-	ImmA/IrrE family metallo-endopeptidase	A0A0S2SXM3	Bacillus_phage	2.0e-16	36.8
WP_069291302.1\|4133131_4133605_-	helix-turn-helix domain-containing protein	S6C481	Thermus_phage	2.1e-19	40.4
WP_013309118.1\|4133937_4134414_+	transcriptional regulator	A0A0C5AJ96	Bacteriophage	9.0e-42	61.9
WP_069291303.1\|4134776_4135745_+	hypothetical protein	NA	NA	NA	NA
WP_013309120.1\|4135755_4135974_+	hypothetical protein	NA	NA	NA	NA
WP_069291304.1\|4135976_4137443_+\|tail	phage tail sheath subtilisin-like domain-containing protein	A0A0N7AEC6	Bacillus_phage	1.8e-72	36.1
WP_007429163.1\|4137565_4137973_+\|tail	phage tail tube protein	A0A2H4J032	uncultured_Caudovirales_phage	3.2e-40	61.1
WP_007429164.1\|4138049_4138484_+	hypothetical protein	A0A2H4J883	uncultured_Caudovirales_phage	1.8e-20	42.0
WP_061830305.1\|4138660_4140427_+	hypothetical protein	NA	NA	NA	NA
WP_061830304.1\|4140463_4141108_+	LysM peptidoglycan-binding domain-containing protein	A0A0N7ACF7	Bacillus_phage	1.9e-42	51.3
WP_069291305.1\|4141104_4142082_+\|portal	phage portal protein	A0A0N6W8H4	Bacillus_phage	3.2e-78	47.4
WP_069291306.1\|4142074_4142482_+	hypothetical protein	A0A0N7ACD3	Bacillus_phage	2.3e-09	33.1
WP_069291307.1\|4142474_4142939_+	DUF2634 domain-containing protein	A0A0N7ACH4	Bacillus_phage	9.8e-25	37.9
WP_069291308.1\|4142938_4144090_+\|plate	baseplate J/gp47 family protein	S6AVU3	Thermus_phage	3.2e-40	34.4
WP_069291309.1\|4144082_4144757_+	YmfQ family protein	A0A0A7RTU9	Clostridium_phage	8.0e-28	43.8
WP_069291310.1\|4144758_4147350_+	hypothetical protein	R4JDZ8	Bacillus_phage	1.8e-19	28.4
WP_069291311.1\|4147362_4147974_+	hypothetical protein	NA	NA	NA	NA
WP_069291312.1\|4148035_4148302_+	hypothetical protein	NA	NA	NA	NA
WP_069292085.1\|4148527_4149295_+	YmfQ family protein	A0A090D815	Clostridium_phage	7.5e-14	36.2
WP_069291313.1\|4149337_4149727_+\|tail	phage tail protein	NA	NA	NA	NA
WP_061830295.1\|4150434_4150722_+	hypothetical protein	NA	NA	NA	NA
WP_155765248.1\|4150781_4150925_+	hypothetical protein	NA	NA	NA	NA
WP_040101929.1\|4151014_4151461_+\|holin	phage holin family protein	R9TMD4	Paenibacillus_phage	8.7e-39	62.2

DBSCAN-SWA_8

4458951 : 4533072

Bacillus_phage(16.22%)

coat,head,tail,holin,protease,capsid,terminase,tRNA,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023987770.1\|4458951_4459965_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2K9L3A8	Tupanvirus	1.1e-33	36.6
WP_069291474.1\|4459993_4462441_+\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_069291475.1\|4462650_4464675_+	DNA repair protein	NA	NA	NA	NA
WP_023987773.1\|4464823_4465183_-\|holin	phage holin family protein	NA	NA	NA	NA
WP_069291476.1\|4465335_4467705_+	endonuclease MutS2	Q94M10	Lactobacillus_phage	1.5e-12	33.9
WP_013309402.1\|4467763_4468177_+	DUF350 domain-containing protein	NA	NA	NA	NA
WP_069291477.1\|4468231_4468939_+	hypothetical protein	NA	NA	NA	NA
WP_061829135.1\|4469055_4470309_+	MFS transporter	NA	NA	NA	NA
WP_069291478.1\|4470389_4471628_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_061829136.1\|4471741_4471978_+	hypothetical protein	NA	NA	NA	NA
WP_029516490.1\|4472009_4472396_+\|coat	spore coat protein	NA	NA	NA	NA
WP_013370105.1\|4472539_4473040_+	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_061829137.1\|4473052_4474264_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_069291479.1\|4474378_4474585_+	aspartyl-phosphate phosphatase Spo0E family protein	NA	NA	NA	NA
WP_069291480.1\|4474685_4475255_+	hypothetical protein	NA	NA	NA	NA
WP_061829140.1\|4475273_4475837_+	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
WP_069291481.1\|4475858_4476818_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_069291482.1\|4476860_4477226_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	4.4e-20	48.6
WP_080710677.1\|4477298_4478195_+	flap endonuclease	F8WQ40	Bacillus_phage	4.4e-21	31.9
WP_069291483.1\|4478417_4479296_+	ROK family protein	NA	NA	NA	NA
WP_069291484.1\|4479462_4480470_+	HRDC domain-containing protein	NA	NA	NA	NA
WP_023987788.1\|4480631_4481567_-	magnesium/cobalt transporter CorA	NA	NA	NA	NA
WP_061829145.1\|4482364_4483282_+	homoserine O-succinyltransferase	NA	NA	NA	NA
WP_043882120.1\|4483407_4484592_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	A0A0B5JD48	Pandoravirus	4.7e-15	28.1
WP_069291485.1\|4484588_4485767_+	aminotransferase class V-fold PLP-dependent enzyme	NA	NA	NA	NA
WP_061829148.1\|4486199_4487333_+	dehypoxanthine futalosine cyclase	A9ZMK9	Mamastrovirus	9.1e-24	46.6
WP_069292094.1\|4487429_4488293_-	YitT family protein	NA	NA	NA	NA
WP_023987794.1\|4488377_4489604_-	cation:proton antiporter	NA	NA	NA	NA
WP_069291486.1\|4489608_4490103_-	cation:proton antiporter regulatory subunit	NA	NA	NA	NA
WP_069291487.1\|4490309_4490705_-	hypothetical protein	NA	NA	NA	NA
WP_061829150.1\|4490945_4491827_+	putative sporulation protein YtxC	NA	NA	NA	NA
WP_069291488.1\|4491888_4492464_+	3D domain-containing protein	J9PQW7	Bacillus_phage	3.3e-14	39.3
WP_069291489.1\|4492548_4492857_+	hypothetical protein	NA	NA	NA	NA
WP_061829154.1\|4493052_4494639_+	trypsin-like peptidase domain-containing protein	A0A1B1IT49	uncultured_Mediterranean_phage	1.2e-18	26.5
WP_069291490.1\|4494788_4495478_+	response regulator transcription factor	W8CYM9	Bacillus_phage	6.5e-41	42.5
WP_069291491.1\|4495479_4496958_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	6.7e-27	27.4
WP_013309434.1\|4497069_4498026_+	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NA	NA	NA	NA
WP_013309435.1\|4498290_4499328_+	3-deoxy-7-phosphoheptulonate synthase	E3T537	Cafeteria_roenbergensis_virus	6.2e-11	27.0
WP_061829159.1\|4499599_4501024_+	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_081112429.1\|4501289_4502381_+	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	4.4e-92	47.0
WP_061829161.1\|4502620_4503085_+\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
WP_013309439.1\|4503462_4503711_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A2I7SC16	Paenibacillus_phage	4.9e-15	43.9
WP_069291492.1\|4503809_4504877_-	phosphodiester glycosidase family protein	A0A2H4JHN3	uncultured_Caudovirales_phage	2.3e-05	29.1
WP_013309441.1\|4504873_4505281_-	hypothetical protein	NA	NA	NA	NA
WP_069291493.1\|4505557_4506214_+	response regulator transcription factor	NA	NA	NA	NA
WP_061829165.1\|4506264_4507518_+	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_069291494.1\|4507537_4508371_-	hypothetical protein	NA	NA	NA	NA
WP_069291495.1\|4509522_4511172_-	recombinase family protein	O64015	Bacillus_phage	8.3e-119	41.5
WP_069291496.1\|4511437_4511695_+	hypothetical protein	NA	NA	NA	NA
WP_069291497.1\|4511768_4512176_-	type II toxin-antitoxin system HicB family antitoxin	A0A0C5ABG6	Paenibacillus_phage	6.7e-46	63.6
WP_019686665.1\|4512320_4512536_-	type II toxin-antitoxin system HicA family toxin	A0A0C5AED5	Paenibacillus_phage	3.0e-21	69.0
WP_069291498.1\|4512636_4512966_+	HNH endonuclease	A0A2I7SC48	Paenibacillus_phage	1.4e-25	60.9
WP_069291499.1\|4513129_4513480_+\|terminase	P27 family phage terminase small subunit	A0A0U4JV93	Exiguobacterium_phage	1.1e-31	64.5
WP_069291500.1\|4513476_4515204_+\|terminase	terminase large subunit	A6XMJ4	Bacillus_virus	8.1e-266	73.6
WP_081330738.1\|4515205_4516408_+\|portal	phage portal protein	A6XMJ5	Bacillus_virus	1.2e-172	74.1
WP_069291502.1\|4516400_4516973_+\|head,protease	HK97 family phage prohead protease	Q0H262	Geobacillus_phage	2.6e-75	72.3
WP_069291503.1\|4516975_4518286_+\|capsid	phage major capsid protein	A0A0U4IB53	Exiguobacterium_phage	1.9e-97	58.9
WP_069291504.1\|4518282_4518840_+	hypothetical protein	NA	NA	NA	NA
WP_069291505.1\|4518841_4519117_+	hypothetical protein	Q0H259	Geobacillus_phage	3.9e-29	74.4
WP_069291506.1\|4519113_4519425_+\|head	phage head closure protein	A6XMK0	Bacillus_virus	2.2e-28	62.1
WP_069291507.1\|4519417_4519804_+	HK97 gp10 family phage protein	A6M956	Geobacillus_virus	6.9e-24	47.6
WP_069291508.1\|4519803_4520139_+	hypothetical protein	A6M957	Geobacillus_virus	9.5e-30	61.8
WP_069291509.1\|4520143_4520746_+\|tail	phage tail protein	A6M958	Geobacillus_virus	5.6e-65	63.4
WP_069291510.1\|4520742_4521132_+	hypothetical protein	A6M959	Geobacillus_virus	1.1e-18	43.0
WP_172828306.1\|4521145_4521313_+	hypothetical protein	NA	NA	NA	NA
WP_069291511.1\|4521330_4525782_+\|tail	phage tail tape measure protein	A6M961	Geobacillus_virus	2.7e-31	34.8
WP_081330739.1\|4525778_4526345_+\|tail	phage tail family protein	A0A290FZP5	Caldibacillus_phage	1.4e-17	35.6
WP_069291512.1\|4526357_4526768_+	hypothetical protein	H6BJ44	Methylophilales_phage	3.3e-24	41.6
WP_069292096.1\|4526786_4527887_+\|tail	tail fiber protein	A0A127KNF8	Pseudomonas_phage	1.1e-10	72.7
WP_069291513.1\|4527883_4528264_+	hypothetical protein	NA	NA	NA	NA
WP_019686685.1\|4528260_4528401_+	XkdX family protein	G3MAH0	Bacillus_virus	2.0e-10	63.0
WP_069291514.1\|4528433_4529060_+\|tail	phage tail family protein	NA	NA	NA	NA
WP_069291515.1\|4529068_4530985_+\|tail	phage tail protein	A0A0U4B063	Bacillus_phage	1.8e-133	49.9
WP_069291516.1\|4530978_4531524_-	hypothetical protein	NA	NA	NA	NA
WP_069291517.1\|4531763_4532228_+\|holin	phage holin family protein	R9TMD4	Paenibacillus_phage	3.7e-40	63.0
WP_081330740.1\|4532241_4533072_+	glycoside hydrolase family 25 protein	D0R7H8	Paenibacillus_phage	1.7e-67	60.2

DBSCAN-SWA_9

4692455 : 4701807

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_069292098.1\|4692455_4693325_+	glucose 1-dehydrogenase	A0A2N9QUX2	Trichoplusia_ni_ascovirus	1.9e-53	42.6
WP_069291604.1\|4693444_4695247_+	HAMP domain-containing protein	W8CYF6	Bacillus_phage	5.5e-39	37.3
WP_013309604.1\|4695375_4696107_+	response regulator transcription factor	W8CYM9	Bacillus_phage	9.3e-38	35.3
WP_069291605.1\|4696266_4697391_+	CBS domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	1.4e-05	35.4
WP_013309606.1\|4697518_4698277_+	phosphate ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.0e-14	32.4
WP_025721993.1\|4698316_4698976_+	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_069291606.1\|4699152_4701807_+	DNA polymerase I	A0A060AM05	Listeria_phage	1.5e-45	29.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP015423

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection