CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP014907	Lactobacillus lindneri strain TMW 1.481 chromosome, complete genome	1 crisprs	csn2,cas2,cas1,cas9,csa3,DinG,DEDDh,cas3	2	9	4	1
NZ_CP014909	Lactobacillus lindneri strain TMW 1.481 plasmid pL1481-2	0 crisprs	NA	0	0	0	0
NZ_CP014910	Lactobacillus lindneri strain TMW 1.481 plasmid pL1481-3	0 crisprs	NA	0	0	0	0
NZ_CP014908	Lactobacillus lindneri strain TMW 1.481 plasmid pL1481-1, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP014911	Lactobacillus lindneri strain TMW 1.481 plasmid pL1481-4	1 crisprs	NA	0	1	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP014907_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014907_1

134553-135514

TypeII

Consensus_repeat	Method
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	CRISPRCasFinder
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	CRT
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	PILER-CR

14 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP014907_1

>merge|NZ_CP014907|1|134553-135514|CRISPRCasFinder,CRT,PILER-CR
ATTCTTAATCTCATTAGAATGACGTAATTCTAAAACTTGCGGTAAGTTGATCTCTTTACTTAATTTGTTCTTAATCTCATTAGAATGACGTACTTCTAAAACTTGCGTATAGCTTCATTAGTTGTTAACGTAGTTATTAATCTCATTAGAATGACGTACTTCTAAAACCGTCTCCGGACTAAAATTGCTGTCCGCCCAGTTCTTAATCTCATTAGAATGACGTACTTCTAAAACAATGTGTCAAGCTGTTGTAGATCCTGTTAGGTTCTTAATCTCATTAGAATGACGTACTTCTAAAACACAAGCTGATGAATTAATGAAACGTTCATTAGTTCTTAATCTCATTAGAATGACGTACTTCTAAAACGCTCCCACCTGAATTATGATTTGGTGGCTGGTTCTTAATCTCATTAGAATGACGTACTTCTAAAACCCTACTGGAACAACAAATGGGTCGAATTCAGTTCTTAATCTCATTAGAATGACGTACTTCTAAAACTAAGGACATTCATCATAGATTATTTAAGGGGTTCTTAATCTCATTAGAATGACGTACTTCTAAAACCCACTTCTTGGTCGAATTGGAAAACAATCAGGTTCTTAATCTCATTAGAATGACGTACTTCTAAAACGTATCTTGTAAATGAATTCAAATTGATTCAGTTCTTAATCTCATTAGAATGACGTACTTCTAAAACTTAATTGTAATATTCTTTGACCCTTGAGGGGTTCTTAATCTCATTAGAATGACGTACTTCTAAAACATCAGCAGTCTTTGAGTATGCTTTAGCATAGTTCTTAATCTCATTAGAATGACGTACTTCTAAAACCTGGGGACTTGATAACCTCAGCAGTATAAGGTTCTTAATCTCATTAGAATGACGTACTTCTAAAACGCTGCGATCAAAACATCATAGAATTGCTTCGTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC

>NZ_CP014907|1|1|134553-135514|CRISPRCasFinder
ATTCTTAATCTCATTAGAATGACGTAATTCTAAAAC	TTGCGGTAAGTTGATCTCTTTACTTAATTT
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	TTGCGTATAGCTTCATTAGTTGTTAACGTA
GTTATTAATCTCATTAGAATGACGTACTTCTAAAAC	CGTCTCCGGACTAAAATTGCTGTCCGCCCA
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	AATGTGTCAAGCTGTTGTAGATCCTGTTAG
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	ACAAGCTGATGAATTAATGAAACGTTCATTA
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	GCTCCCACCTGAATTATGATTTGGTGGCTG
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	CCTACTGGAACAACAAATGGGTCGAATTCA
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	TAAGGACATTCATCATAGATTATTTAAGGG
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	CCACTTCTTGGTCGAATTGGAAAACAATCAG
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	GTATCTTGTAAATGAATTCAAATTGATTCA
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	TTAATTGTAATATTCTTTGACCCTTGAGGG
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	ATCAGCAGTCTTTGAGTATGCTTTAGCATA
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	CTGGGGACTTGATAACCTCAGCAGTATAAG
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	GCTGCGATCAAAACATCATAGAATTGCTTC
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC

>NZ_CP014907|1|1|134553-135514|CRT
ATTCTTAATCTCATTAGAATGACGTAATTCTAAAAC	TTGCGGTAAGTTGATCTCTTTACTTAATTT
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	TTGCGTATAGCTTCATTAGTTGTTAACGTA
GTTATTAATCTCATTAGAATGACGTACTTCTAAAAC	CGTCTCCGGACTAAAATTGCTGTCCGCCCA
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	AATGTGTCAAGCTGTTGTAGATCCTGTTAG
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	ACAAGCTGATGAATTAATGAAACGTTCATTA
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	GCTCCCACCTGAATTATGATTTGGTGGCTG
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	CCTACTGGAACAACAAATGGGTCGAATTCA
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	TAAGGACATTCATCATAGATTATTTAAGGG
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	CCACTTCTTGGTCGAATTGGAAAACAATCAG
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	GTATCTTGTAAATGAATTCAAATTGATTCA
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	TTAATTGTAATATTCTTTGACCCTTGAGGG
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	ATCAGCAGTCTTTGAGTATGCTTTAGCATA
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	CTGGGGACTTGATAACCTCAGCAGTATAAG
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	GCTGCGATCAAAACATCATAGAATTGCTTC
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC

>NZ_CP014907|1|1|134685-135514|PILER-CR
GTTATTAATCTCATTAGAATGACGTACTTCTAAAAC	CGTCTCCGGACTAAAATTGCTGTCCGCCCA
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	AATGTGTCAAGCTGTTGTAGATCCTGTTAG
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	ACAAGCTGATGAATTAATGAAACGTTCATTA
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	GCTCCCACCTGAATTATGATTTGGTGGCTG
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	CCTACTGGAACAACAAATGGGTCGAATTCA
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	TAAGGACATTCATCATAGATTATTTAAGGG
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	CCACTTCTTGGTCGAATTGGAAAACAATCAG
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	GTATCTTGTAAATGAATTCAAATTGATTCA
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	TTAATTGTAATATTCTTTGACCCTTGAGGG
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	ATCAGCAGTCTTTGAGTATGCTTTAGCATA
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	CTGGGGACTTGATAACCTCAGCAGTATAAG
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC	GCTGCGATCAAAACATCATAGAATTGCTTC
GTTCTTAATCTCATTAGAATGACGTACTTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014907.1\|WP_065868657.1\|129571_130636_-\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|226957
NZ_CP014907.1\|WP_054646817.1\|131340_132099_+\|glucose-1-dehydrogenase	unknown	unknown	gnl\|CDD\|187600
NZ_CP014907.1\|WP_054646788.1\|127136_128003_-\|phosphate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270371
NZ_CP014907.1\|WP_054646654.1\|143930_144791_-\|energy-coupling-factor-transporter-ATPase	unknown	unknown	gnl\|CDD\|275314
NZ_CP014907.1\|WP_054646782.1\|133223_133721_-\|GtrA-family-protein	unknown	unknown	gnl\|CDD\|377229
NZ_CP014907.1\|WP_054646784.1\|130646_131150_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NZ_CP014907.1\|WP_054646653.1\|144775_145606_-\|energy-coupling-factor-transporter-ATPase	unknown	unknown	gnl\|CDD\|275313
NZ_CP014907.1\|WP_054646661.1\|135534_136200_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd12218_csn2_CAS-II-A	gnl\|CDD\|213411
NZ_CP014907.1\|WP_054646652.1\|145678_146281_-\|ECF-transporter-S-component	unknown	unknown	gnl\|CDD\|227029
NZ_CP014907.1\|WP_054646783.1\|132385_133153_-\|nicotinamide-mononucleotide-transporter	unknown	unknown	gnl\|CDD\|273672
NZ_CP014907.1\|WP_054646655.1\|143140_143938_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NZ_CP014907.1\|WP_054646660.1\|136196_136502_-\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0206_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|226043
NZ_CP014907.1\|WP_054646657.1\|141732_142584_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014907.1\|WP_054646658.1\|137585_141611_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	mkCas0193_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|374653
NZ_CP014907.1\|WP_054646781.1\|133726_134092_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014907.1\|WP_103422850.1\|128217_128838_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP014907.1\|WP_054646786.1\|128897_129569_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_CP014907.1\|WP_054646659.1\|136479_137385_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_CP014907.1\|WP_054646656.1\|142674_143091_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014907.1\|WP_141117424.1\|132170_132368_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP014907.1\|WP_065868657.1\|129571_130636_-\|FtsX-like-permease-family-protein	gnl\|CDD\|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	6.54285e-10
NZ_CP014907.1\|WP_054646782.1\|133223_133721_-\|GtrA-family-protein	gnl\|CDD\|377229	pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of undecaprenyl phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane. Another member of this family is a DTDP-glucose-4-keto-6-deoxy-D-glucose reductase, which catalyzes the conversion of dTDP-4-keto-6-deoxy-D-glucose to dTDP-D-fucose, which is involved in the biosynthesis of the serotype-specific polysaccharide antigen of Actinobacillus actinomycetemcomitans Y4 (serotype b). This family also includes the teichoic acid glycosylation protein, GtcA, which is a serotype-specific protein in some Listeria innocua and monocytogenes strains. Its exact function is not known, but it is essential for decoration of cell wall teichoic acids with glucose and galactose.	3.9613e-06
NZ_CP014907.1\|WP_054646788.1\|127136_128003_-\|phosphate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270371	cd13653, PBP2_phosphate_like_1, Substrate binding domain of putative ABC-type phosphate transporter, a member of the type 2 periplasmic binding fold superfamily. This subfamily contains uncharacterized phosphate binding domains found in PstS proteins that serve as initial receptors in the ABC transport of phosphate in eubacteria and archaea. After binding the ligand, PstS interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The PstS proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	7.97231e-91
NZ_CP014907.1\|WP_054646654.1\|143930_144791_-\|energy-coupling-factor-transporter-ATPase	gnl\|CDD\|275314	TIGR04521, ECF_ATPase_2, energy-coupling factor transporter ATPase. Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate].	2.15035e-150
NZ_CP014907.1\|WP_054646817.1\|131340_132099_+\|glucose-1-dehydrogenase	gnl\|CDD\|187600	cd05341, 3beta-17beta-HSD_like_SDR_c, 3beta17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs. This subgroup includes members identified as 3beta17beta hydroxysteroid dehydrogenase, 20beta hydroxysteroid dehydrogenase, and R-alcohol dehydrogenase. These proteins exhibit the canonical active site tetrad and glycine rich NAD(P)-binding motif of the classical SDRs. 17beta-dehydrogenases are a group of isozymes that catalyze activation and inactivation of estrogen and androgens, and include members of the SDR family. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	1.31537e-106
NZ_CP014907.1\|WP_054646784.1\|130646_131150_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	0.000261362
NZ_CP014907.1\|WP_054646653.1\|144775_145606_-\|energy-coupling-factor-transporter-ATPase	gnl\|CDD\|275313	TIGR04520, ECF_ATPase_1, energy-coupling factor transporter ATPase. Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate].	3.04714e-139
NZ_CP014907.1\|WP_054646661.1\|135534_136200_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213411	cd12218, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	1.17392e-54
NZ_CP014907.1\|WP_054646652.1\|145678_146281_-\|ECF-transporter-S-component	gnl\|CDD\|227029	COG4684, COG4684, Predicted membrane protein [Function unknown].	4.91329e-15
NZ_CP014907.1\|WP_054646783.1\|132385_133153_-\|nicotinamide-mononucleotide-transporter	gnl\|CDD\|273672	TIGR01528, Protein_pnuC., nicotinamide mononucleotide transporter PnuC. The PnuC protein of E. coli is membrane protein responsible for nicotinamide mononucleotide transport, subject to regulation by interaction with the NadR (also called NadI) protein (see TIGR01526). This model defines a region corresponding to most of the length of PnuC, found primarily in pathogens. The extreme N- and C-terminal regions are poorly conserved and not included in the alignment and model. [Transport and binding proteins, Other, Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides].	4.86396e-24
NZ_CP014907.1\|WP_054646655.1\|143140_143938_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	5.07371e-38
NZ_CP014907.1\|WP_054646660.1\|136196_136502_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	4.25379e-28
NZ_CP014907.1\|WP_054646658.1\|137585_141611_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|374653	pfam16592, Cas9_REC, REC lobe of CRISPR-associated endonuclease Cas9. The REC lobe of Cas9 - the CRISPR-associated endonuclease Cas9 - includes the REC1 and REC2 domains. REC1 forms an elongated, alpha-helical structure consisting of 25 alpha helices and two beta-sheets, whereas REC2 inserted within REC1 adopts a six-helix bundle structure. The REC lobe and the NUC lobe of Cas9 fold to present a positively charged groove at their interface which accommodates the negatively charged sgRNA:target DNA heteroduplex. CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system occurs naturally in bacteria as a defense against invasion by phages or other mobile genetic elements. Cas9 is targeted to specific genomic locations by sgRNAs or single guide RNAs, in order to complex with invading DNA in order to cleave it and render it inactive.	1.49832e-176
NZ_CP014907.1\|WP_103422850.1\|128217_128838_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.85534e-44
NZ_CP014907.1\|WP_054646786.1\|128897_129569_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	4.03507e-84
NZ_CP014907.1\|WP_054646659.1\|136479_137385_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	3.12318e-87

>NZ_CP014907.1|WP_054646781.1|133726_134092_-|hypothetical-protein
MADKQFIANKVLEKERQVIGTTPDENKDTVDFRVAVALGNNSSYYLDSTKCSKSSLGNLYTSWLTTYINSPAIIKSSNKMVTSFINDYDFRDDVDDAFNETFQKYLNGEMSIDDIKQTLMD
>NZ_CP014907.1|WP_054646782.1|133223_133721_-|GtrA-family-protein
MRRRIKNIIFDQRIKYLFWGVLTTLVYFVVRIISMSFFSNPEIPVVISETVSIIFAFLVNKFFVFNTEKQSKELTSQIVDFFIGRGIAFGIDFVLTYLLIQKFADFFIKLIGLNRIDYHAQIFQIPLIHNHLGSPELINSFLVIIFIQIVIIIFNYFISKYWAFK
>NZ_CP014907.1|WP_054646783.1|132385_133153_-|nicotinamide-mononucleotide-transporter
MQLELYLKQFYAGFRKTFSIKNNFHDIKSFQKSTKIILMINLLVTFITFGVSHEFSSWIGWVSLFASIFSLVNLMLCDEGKITNYSWGLLESLLFLLIDVENRLIGDLATNIYYLITQTLGIFFWGNLLSQQDQQTKINPRKLTKLQLFLLGIGLVVIYVVVIIISKKLNGTQIYLDATILPLSIVGMILMIGGYRFQWVIWIAWDIVSLIIWFRQFQSLSPASASMLALEVMKLVNGFYGAYMWFFKNKAANTD
>NZ_CP014907.1|WP_141117424.1|132170_132368_-|hypothetical-protein
MVTFFAILLLLILFGSWFIKSDCCSSIIFLIVFLFLISLFINLVWLWLPIILILIVLALFTGRHG
>NZ_CP014907.1|WP_054646817.1|131340_132099_+|glucose-1-dehydrogenase
MSQRLTGKVAIITGGSKGIGFATARRFAQEGAAVVITARNETEGNKAATAINQEFPDSVKFKKQDVSNSERWTEIFAETKDDFGPVTTLVNNAGIGIGKSIEETTDEEWQKVIGIDLTGTFYGIREGIRQMKNKNNGASIINISSIEGIVGDPILGAYNASKGGVKMMSKSAALDCALKDYGVRVNCVNPGYIKTPMISDELDQYMSQRSKTPMGHLGKPDDIAYACVYLASDESAFTTGSEMVVDGGYTAQ
>NZ_CP014907.1|WP_054646784.1|130646_131150_-|helix-turn-helix-transcriptional-regulator
MPSQTFDNLSHEKQIRIQKALLDEFSHYSLAEAQVARIVKEAKIARGAFYKYFADLTDAYQYEFKMVMREIHRPLKGGQTKLSPNAILTMISDFINESENAHVREFVTLYYQKNRYLLSPSQAELELSGSKWGVSILIHQTIRDILLQPQQQPFFLRRLKENLEKLS
>NZ_CP014907.1|WP_065868657.1|129571_130636_-|FtsX-like-permease-family-protein
MFLALKEIKHYKLRYGLIVTMIVLISYLIFILTSLAVGLSTQNTKAIDSWKPQRIVLNKDSNINISRSVITKEQGKNLKINPKQDAYVENAPVVSSAKDRSRVSAQFVGLDPHQYIYQNLKLTSGHKAQKNHQVVVDTQFQQNGYHLGDKIKLNSDNHSYEIVGFTKNAKLSIAPVVYGSMDDWRQLHNLTSDFLCSAVISKNADYKAHNSDLYAYSAKKVIDELPGYQAQNSIFTFMIAFLMIISLIVIAVFLYILTMQKLENYAVLRAQGIPAGVLVRATLFQTFILVISGIVIGVVLTLLTTMALGNSVPVACDPLIMSTTVIGLLVTSMLGALIPSIMILKVDPADAIGG
>NZ_CP014907.1|WP_054646786.1|128897_129569_-|ABC-transporter-ATP-binding-protein
MDAIKLTNVSKSFGQADNRFQVLDNINFTSKRGEVNIITGPSGSGKSTLLTIMGALRDPDEGTVLLENEKVANLSAKARDQFRLNQIGFILQAHTLVPYLTVRDQFVLVDKVRPEGNMSAAELQNLTDRLGVSRVVDHFPNELSGGQSQRVAIIRGIYTKPNIILADEPTASLDEQRVTEVCQLLSDLAKKENKTVVVVTHDERVNQYADHIYELVDGHLSEK
>NZ_CP014907.1|WP_103422850.1|128217_128838_+|response-regulator-transcription-factor
MKHFKTVMLQKKSVGIFWDLTTFPYADYQAELTKIRNTYQIPILMLDNDKNNVLQVLQAGFDDYLIKPYSYLELIARLEQKQKLYQQLVVPENAPKLPTQPKIIIDDVVIDQQKYKAFKNHKDLGLTPKELKLLLYLIKHDSQVLSRQQLLEGVWGDYYDISQTTRMVDIHISHLRDKIEKDPKKPTIIKTVRGFGYQFIGDYITK
>NZ_CP014907.1|WP_054646788.1|127136_128003_-|phosphate-ABC-transporter-substrate-binding-protein
MHYQRLLPICLAAVGILMLTGCGSKNKQNTVTAVGSTAMQPLVQKAGSDYQAEHPKVSITVQGGGSGTGLSQVETGAVNIGDSDIFAEQKDGIHAKKLIDHQVAVVGIAPITNPKNGVNNLSEKQLENIFLGKIKNWKEVGGKDLPIIVINRAQGSGTRSTFEKSVLKGKDAVKSQEQDSNGTVQKIVENTPGTISYLSLPYLNNQVKVLSVDHIQPNYQNITTNRWKIWSYEHMYTNKQPSPTTKKFIAYIMSKPTQQKLVKAAGYVSIHDMKVQMDAAGKVTHKPK
>NZ_CP014907.1|WP_054646661.1|135534_136200_-|type-II-A-CRISPR-associated-protein-Csn2
MKLTIYPQKPFVIENGILTVLQTNNSKFYSDLIIGLSRHNNIIVSDNDGIIDTQENLVYLDNVISNPNLFLPFKLKLENLIIEDLNENERQRLFQLDREIKSIFLGASYLEDIPMSIDEEWSLKKLYKYSGIDVLKSAIDNPYDIIKVVLNSYKKFYPKKLIVLNVLFNYLDSSQISNLIQMIKDLDLYVLILNFSSQPYSKLFEKCRYYSVDSDFVRFDR
>NZ_CP014907.1|WP_054646660.1|136196_136502_-|CRISPR-associated-endonuclease-Cas2
MRLIVMFDLPVDTSEERRNYRKFRKELINEGFLMIQYSVYARVCVSKQSAKFTENRIRTFLPAKGLIQTLMVTEKQYNSMHFLIGDKKDDVRNTSDRTVVI
>NZ_CP014907.1|WP_054646659.1|136479_137385_-|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTVVVTQHAKISYSGRRIIVQTNAAINEIPIDDIEILMISTTQAVITSRAISELAKMSVSVVFSDTTGEPVCETVDYMPNNRSVSLLHKQFEWDKSRKELLWTWIVTEKIKMQIEILQKKRINTEDLDYEFRKIEIDDLTNREAVVARKYFPLLFEEGFERRTFNPYNAALNYGYSILLSFVNRNIVTNGCLTQLGIHHKNDENQFNLGSDLMEPFRPIIDWWVSEQEIKELSSDIKIGLIDLFNLEIKFNGKRTILRNALKTHVANCIKYLNGEKDEVKIEVELGDEISRNEINSNV
>NZ_CP014907.1|WP_054646658.1|137585_141611_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MTQKVIPYNIGLDIGTNSVGWAVTDNENKLLHIKGHNGIGVRLFKEGQSAAERCGFRTTRRRLSRRKWRLRLLNEIFADKIAKVDPSFFARLKQSNVSPKDPNKTMFGNILFDNGNLNDKSFHDEYKTIYHLRQSIIDHPEKKFDIRLIYLAMHHIIKYRGHFLNQANVQDFKGGKIDLEESFKDLNSIFENQGRDLRLVTEDANKYVKELSDNSKTRNDRQKELSKVLYIPIDKNSDKNNKKVTTEIIKAILGMKAKFDVIFGIDAENAKEWSLTFNSDDFDDKIEGLSAQMTDEAGEILLILKELYFALNLSDILNNSVTDKNAKTLSEAMINRYDDHKEQLTMLKQVIDNSDKKHAKALKAAYSAYIDGENNKKISFEDLRKRIQKNLDNSETSKKINDLLEHDYFLPKQRSKENGAIPHQLQQQELDKIIESQKHYYPFLAELNPNEKRSRQAKYKLDELVAFRVPYYVGPMVKATENNQSNNGKFAWMIKNDNISDKLKKEEITPWNFDKKVDRTETATKFITRMTTTDTYLIGEPVLPKNSLLYQKFVVLNELNNLKINKQPITPEQKQYVYEHVMKQTKRVSLKKIADALVIKGDYPYAPEITGTTDQKNMNNGLSTYIDLAKIFGDELDDIDRKEDFEKIIEWSTIFEDQHIFALKLKEIKWLTEDQRKQVVKLRYQGWGKLSKKLLADLVDDNGQRIIDLLWDSKQDFMQIVNQNSFKQAIAEHNGAHLEEKDLKDIINNLYTSPQNKKAIRQVILVVDDIIRAVGYEPVNIMMEFAREDSKDHRLTNSRSRQLEKVYKDITNSWFDDDNVKDELKDKIKDKAKFTDRLYLYFTQGGKDLYTGEPLDIDNLSNYQIDHILPQSFILDNSLDNRVLTSKINNQIKKDNLPGEFFGSKMHNFWKHLKELHLISNKKYYNLTLTPNSISKFNNQGRFINRQLVETRQVIKLAAEILHNRYSEENGTNIVTVKANLTHHMREKFNFYKNRNVNDYHHAFDAYLAAFVGNWLLQQYPKLKPYFVYGDFAKTEIDNLKSFNLIYKFEQAHQLNEEDGKIAKDTDALLGYMKNVYHFKKMLVTKELETNHGNLFKQTLYPSHGKMKNLINPKENRSSDIYGGYSSETGAYVSLIKVFKKNKIENKIIKIPLLYIDKLNRQANAKQFIRNFIIKDDSNKFDILSEKIFLNQLVIDGDELFTISGSGDRQNAQQLILSDKSLKILSKNINVISKNDLIIIFNEIIDDICKYMKMYEVENSDETKAKFEEINDKDRMLKIINDLLLGLHANASRSNLSSIGLSPSFGRFFSGNAGIKLSENAKFIYQSPTGLFSRKVKISDL
>NZ_CP014907.1|WP_054646657.1|141732_142584_+|hypothetical-protein
MTSTTIYQLTWQTFQLFLLLSVSLIGLPLLTGFLTAKLGKFTQGTLVRGFTDKAQYWLGGLGVIIHELGHLFFSLLFFHRIKKLTLLNFSHREDGSLGSVITSHDKGNWYQAVGNFFIGLAPMFSGIFVIWLLLKFLCHPFYSVISVPPLLNQNFSIINYVDFALKTAYGWLTNIFTAFLTCGLVNQIILLILIGLISTTTFSLSNADLKSSLQGAKVYLILVLVLAIIASIILYYRPDLNYFLNHFVLLSIAFWLVLFILISVCLLISWLEMKLIICIFHLF
>NZ_CP014907.1|WP_054646656.1|142674_143091_+|hypothetical-protein
MKKKVLLTILSASTIALTGVSTATLSQPNVQASTKSFSKEVQGKWNNQAGDTFKIKDSKATLKVKHGNKKGIYKFKVKEKTKNGYQLKADGKKLDKSNEYSLTTSQSGLMQFNYGKQTIQFDNGSMRVKETSKSTSTN
>NZ_CP014907.1|WP_054646655.1|143140_143938_-|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MNKFIFGQYLPGTTLIYRLNPLLKLITAVLLIIASFVNHSWIGFVILLVICGLLIRMSKVGWKFFLKGTKFFIYIILLTSIIQVLFSKGGQVYWHWGIFTISSFGIHIATLAFFRFLIAIVVLTIYLMTTDPADIAQTIQGICYPLKFVGVNLDDIGLVAAIGLRFVPTLTDEVTNIKNAQKARGIDFQKQSIFSRIKSSVAIFVPLFMNVFRRAEQLASSMILRGYTDGKKRTHLRQLKWSKFDSLALIGVMIGFCGFILIFCI
>NZ_CP014907.1|WP_054646654.1|143930_144791_-|energy-coupling-factor-transporter-ATPase
MEIKLKHVGYTYSLNSPLEFTALQDINLAFPTGKFTAVVGKTGSGKSTLIKLLNGLELPTTGEVTVGDQVITNRTKAKQLKQVRKNVGMVFQFPENQLFAETVLKDVMFGPLNFGKSENEAKELAEKWLAEVGIQASLFEQSPFELSGGQMRRVALAGVLACEPEVLVLDEPSAGLDPAGNQNLMQLLKKLQTERGMTIIMVTHSMENVAEFADQVLVMKNGKVIADETPRELFSDSQSLVELPEASQFYLKLMKSRQFNNELPITKNELIKTLVKQFGQKGDQYE
>NZ_CP014907.1|WP_054646653.1|144775_145606_-|energy-coupling-factor-transporter-ATPase
MTEKIIEIKNLTYHYPEKNQNSLKKINLTIHQGEWVSLIGANGSGKSTLAKLIVGLLEDKSKQIQVFGKTMNLENGNELRAQIGMVFQNPENQFVSSTVLDDVAFGLENQGMSREKMNTRVHEALRAVEMENFINHAPSQLSGGQKQRVALAGVLAQRPKLIILDEATSMLDTTTRGKILKVVRKLHESQNTTVLAITHDINETMWSDRIILLNKGEILTQAEPRQLYSQAELLNRCGLTAPLTYQVQQALTKRDIALPQQYLDEEELIKQLWKLN
>NZ_CP014907.1|WP_054646652.1|145678_146281_-|ECF-transporter-S-component
MLRKSKAYRISILALFIAIIMVQNFVPLFGYIPVGPLSLTTIHITVIIAAVMLGPLDGGIVGGVWGLLSFIRAFTAPTSPVEPLIFTNPLISILPRILIGVVAGYVFIALTKTKIKPVLSLVITAVVGSLTNALLVLGMIAIFYRTPAVAHAYGVSDPSLITKVLMATVGTNSIPETILAAIVVPLICLPLLKHRQAKTK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP014907_1	1.9\|135118\|31\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	135118-135148	31	NZ_CP014907.1	941534-941564	1	0.968
NZ_CP014907_1	1.14\|135449\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	135449-135478	30	NZ_CP014907.1	940237-940266	1	0.967

1. spacer 1.9|135118|31|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to position: 941534-941564, mismatch: 1, identity: 0.968

ccacttcttggtcgaattggaaaacaatcag	CRISPR spacer
ccacttattggtcgaattggaaaacaatcag	Protospacer
****** ************************

2. spacer 1.14|135449|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to position: 940237-940266, mismatch: 1, identity: 0.967

gctgcgatcaaaacatcatagaattgcttc	CRISPR spacer
gctgcaatcaaaacatcatagaattgcttc	Protospacer
*****.************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP014907_1	1.2\|134655\|30\|NZ_CP014907\|CRISPRCasFinder,CRT	134655-134684	30	NC_021226	Lactobacillus plantarum subsp. plantarum P-8 plasmid LBPp3, complete sequence	7893-7922	0	1.0
NZ_CP014907_1	1.2\|134655\|30\|NZ_CP014907\|CRISPRCasFinder,CRT	134655-134684	30	NZ_CP021461	Lactobacillus brevis strain ZLB004 plasmid p5, complete sequence	17370-17399	0	1.0
NZ_CP014907_1	1.2\|134655\|30\|NZ_CP014907\|CRISPRCasFinder,CRT	134655-134684	30	NZ_CP017376	Lactobacillus plantarum strain TMW 1.708 plasmid pL1708-2, complete sequence	37879-37908	0	1.0
NZ_CP014907_1	1.2\|134655\|30\|NZ_CP014907\|CRISPRCasFinder,CRT	134655-134684	30	NZ_CP028270	Pediococcus pentosaceus strain SRCM102740 plasmid unnamed1, complete sequence	23631-23660	0	1.0
NZ_CP014907_1	1.2\|134655\|30\|NZ_CP014907\|CRISPRCasFinder,CRT	134655-134684	30	NZ_CP028267	Pediococcus pentosaceus strain SRCM102739 plasmid unnamed1, complete sequence	10337-10366	0	1.0
NZ_CP014907_1	1.2\|134655\|30\|NZ_CP014907\|CRISPRCasFinder,CRT	134655-134684	30	NZ_CP015919	Pediococcus pentosaceus strain wikim20 plasmid pKPP01, complete sequence	12069-12098	0	1.0
NZ_CP014907_1	1.2\|134655\|30\|NZ_CP014907\|CRISPRCasFinder,CRT	134655-134684	30	NZ_CP028265	Pediococcus pentosaceus strain SRCM102738 plasmid unnamed1, complete sequence	32922-32951	0	1.0
NZ_CP014907_1	1.2\|134655\|30\|NZ_CP014907\|CRISPRCasFinder,CRT	134655-134684	30	NZ_CP019582	Lactobacillus helveticus strain LH5 plasmid pCBTLH5_1, complete sequence	12390-12419	0	1.0
NZ_CP014907_1	1.2\|134655\|30\|NZ_CP014907\|CRISPRCasFinder,CRT	134655-134684	30	NZ_CP023007	Pediococcus pentosaceus strain SS1-3 plasmid pSS1301, complete sequence	33363-33392	0	1.0
NZ_CP014907_1	1.2\|134655\|30\|NZ_CP014907\|CRISPRCasFinder,CRT	134655-134684	30	NZ_AP014681	Lactobacillus hokkaidonensis JCM 18461 strain LOOC260 plasmid pLOOC260-1, complete sequence	20483-20512	0	1.0
NZ_CP014907_1	1.2\|134655\|30\|NZ_CP014907\|CRISPRCasFinder,CRT	134655-134684	30	NZ_CP035308	Lactobacillus helveticus strain IDCC3801 plasmid pHel23910, complete sequence	22738-22767	0	1.0
NZ_CP014907_1	1.2\|134655\|30\|NZ_CP014907\|CRISPRCasFinder,CRT	134655-134684	30	NZ_CP031178	Lactobacillus brevis strain UCCLB556 plasmid pUCCLB556_D, complete sequence	23732-23761	0	1.0
NZ_CP014907_1	1.2\|134655\|30\|NZ_CP014907\|CRISPRCasFinder,CRT	134655-134684	30	NZ_CP021928	Pediococcus pentosaceus strain SRCM100194 plasmid pPP194-2, complete sequence	6047-6076	0	1.0
NZ_CP014907_1	1.2\|134655\|30\|NZ_CP014907\|CRISPRCasFinder,CRT	134655-134684	30	NZ_CP029967	Lactobacillus curvatus strain ZJUNIT8 plasmid pnunamed1, complete sequence	29307-29336	0	1.0
NZ_CP014907_1	1.2\|134655\|30\|NZ_CP014907\|CRISPRCasFinder,CRT	134655-134684	30	NZ_CP012188	Lactobacillus paracasei strain CAUH35 plasmid unnamed1, complete sequence	40570-40599	0	1.0
NZ_CP014907_1	1.6\|134920\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134920-134949	30	NC_014164	Lactobacillus acidipiscis cryptic plasmid pLAC1, complete sequence, strain ACA-DC 1533	2162-2191	0	1.0
NZ_CP014907_1	1.2\|134655\|30\|NZ_CP014907\|CRISPRCasFinder,CRT	134655-134684	30	NZ_CP044363	Lactobacillus paracasei strain TD 062 plasmid unnamed2, complete sequence	16420-16449	1	0.967
NZ_CP014907_1	1.2\|134655\|30\|NZ_CP014907\|CRISPRCasFinder,CRT	134655-134684	30	NZ_CP012190	Lactobacillus paracasei strain CAUH35 plasmid unnamed3, complete sequence	21756-21785	1	0.967
NZ_CP014907_1	1.6\|134920\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134920-134949	30	NZ_KF559315	Lactobacillus sakei strain KCA311 plasmid pKCA3, complete sequence	2014-2043	1	0.967
NZ_CP014907_1	1.6\|134920\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134920-134949	30	NC_019353	Leuconostoc mesenteroides subsp. mesenteroides plasmid pMBLR00, complete sequence	1754-1783	1	0.967
NZ_CP014907_1	1.6\|134920\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134920-134949	30	NZ_CP037439	Lactobacillus plantarum strain EM plasmid pEM10, complete sequence	1795-1824	1	0.967
NZ_CP014907_1	1.6\|134920\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134920-134949	30	NZ_CP037439	Lactobacillus plantarum strain EM plasmid pEM10, complete sequence	10251-10280	1	0.967
NZ_CP014907_1	1.6\|134920\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134920-134949	30	NZ_CP037439	Lactobacillus plantarum strain EM plasmid pEM10, complete sequence	18714-18743	1	0.967
NZ_CP014907_1	1.6\|134920\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134920-134949	30	NZ_LM651913	Leuconostoc citreum strain NRRL B-1299 plasmid 1, complete sequence	2496-2525	1	0.967
NZ_CP014907_1	1.6\|134920\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134920-134949	30	NC_006399	Lactobacillus plantarum BIFI-38 plasmid pPB1, complete sequence	1819-1848	2	0.933
NZ_CP014907_1	1.6\|134920\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134920-134949	30	NZ_CP014880	Lactobacillus backii strain TMW 1.1989 plasmid pL11989-7, complete sequence	1269-1298	2	0.933
NZ_CP014907_1	1.6\|134920\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134920-134949	30	NZ_CP014880	Lactobacillus backii strain TMW 1.1989 plasmid pL11989-7, complete sequence	4809-4838	2	0.933
NZ_CP014907_1	1.6\|134920\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134920-134949	30	NZ_CP014906	Lactobacillus backii strain TMW 1.2002 plasmid pL12002-7, complete sequence	1269-1298	2	0.933
NZ_CP014907_1	1.6\|134920\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134920-134949	30	NZ_CP014906	Lactobacillus backii strain TMW 1.2002 plasmid pL12002-7, complete sequence	4809-4838	2	0.933
NZ_CP014907_1	1.6\|134920\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134920-134949	30	NZ_MK167463	Lactobacillus plantarum strain PC518 plasmid pLP325, complete sequence	208-237	3	0.9
NZ_CP014907_1	1.6\|134920\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134920-134949	30	NC_025165	Lactobacillus hilgardii plasmid pLAB1000 or pHL1 sequence	495-524	3	0.9
NZ_CP014907_1	1.6\|134920\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134920-134949	30	KJ868088	Lactobacillus pentosus strain F03 plasmid pF03-1, complete sequence	2265-2294	3	0.9
NZ_CP014907_1	1.7\|134986\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134986-135015	30	NZ_CP033221	Parasedimentitalea marina strain W43 plasmid pW43B, complete sequence	114735-114764	5	0.833
NZ_CP014907_1	1.13\|135383\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	135383-135412	30	MK765551	Tortoise microvirus 1 isolate 1_SP_22, complete genome	716-745	6	0.8
NZ_CP014907_1	1.3\|134721\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134721-134750	30	NZ_CP033036	Agrobacterium fabrum strain 12D13 plasmid pAt12D13a, complete sequence	235406-235435	7	0.767
NZ_CP014907_1	1.3\|134721\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134721-134750	30	NZ_CP033024	Agrobacterium fabrum strain 1D132 plasmid pAt1D132a, complete sequence	165422-165451	7	0.767
NZ_CP014907_1	1.7\|134986\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134986-135015	30	MN693792	Marine virus AFVG_250M943, complete genome	10711-10740	7	0.767
NZ_CP014907_1	1.7\|134986\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134986-135015	30	MN694119	Marine virus AFVG_250M974, complete genome	211-240	7	0.767
NZ_CP014907_1	1.7\|134986\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134986-135015	30	MN694119	Marine virus AFVG_250M974, complete genome	40227-40256	7	0.767
NZ_CP014907_1	1.7\|134986\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134986-135015	30	MN694234	Marine virus AFVG_250M972, complete genome	32430-32459	7	0.767
NZ_CP014907_1	1.7\|134986\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134986-135015	30	MN692978	Marine virus AFVG_117M13, complete genome	31954-31983	7	0.767
NZ_CP014907_1	1.7\|134986\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134986-135015	30	MN694043	Marine virus AFVG_250M973, complete genome	36917-36946	7	0.767
NZ_CP014907_1	1.8\|135052\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	135052-135081	30	NC_018666	Escherichia coli O104:H4 str. 2011C-3493 plasmid pAA-EA11, complete sequence	54717-54746	7	0.767
NZ_CP014907_1	1.8\|135052\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	135052-135081	30	NC_008460	Escherichia coli plasmid pO86A1, complete sequence	8702-8731	7	0.767
NZ_CP014907_1	1.8\|135052\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	135052-135081	30	NC_018662	Escherichia coli O104:H4 str. 2009EL-2071 plasmid pAA-09EL71, complete sequence	26962-26991	7	0.767
NZ_CP014907_1	1.8\|135052\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	135052-135081	30	NZ_CP022087	Escherichia coli O104:H4 strain FDAARGOS_348 plasmid unnamed2, complete sequence	8450-8479	7	0.767
NZ_CP014907_1	1.8\|135052\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	135052-135081	30	NC_022743	Escherichia coli plasmid pHUSEC2011-2, complete sequence	22380-22409	7	0.767
NZ_CP014907_1	1.8\|135052\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	135052-135081	30	NZ_CP031904	Escherichia coli O104:H4 strain FWSEC0009 plasmid unnamed19, complete sequence	15158-15187	7	0.767
NZ_CP014907_1	1.8\|135052\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	135052-135081	30	NC_018654	Escherichia coli O104:H4 str. 2009EL-2050 plasmid pAA-09EL50, complete sequence	48135-48164	7	0.767
NZ_CP014907_1	1.8\|135052\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	135052-135081	30	NZ_CP023530	Escherichia coli strain FDAARGOS_401 plasmid unnamed, complete sequence	38079-38108	7	0.767
NZ_CP014907_1	1.8\|135052\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	135052-135081	30	NZ_CP041001	Escherichia coli strain FDAARGOS_772 plasmid unnamed1, complete sequence	19502-19531	7	0.767
NZ_CP014907_1	1.8\|135052\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	135052-135081	30	NZ_CP023533	Escherichia coli strain FDAARGOS_403 plasmid unnamed2, complete sequence	55952-55981	7	0.767
NZ_CP014907_1	1.8\|135052\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	135052-135081	30	NZ_CP027392	Escherichia coli O104:H4 strain FDAARGOS_349 plasmid unnamed2, complete sequence	36105-36134	7	0.767
NZ_CP014907_1	1.6\|134920\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134920-134949	30	NZ_CP040674	Exiguobacterium mexicanum strain A-EM plasmid punnamed2, complete sequence	943-972	8	0.733
NZ_CP014907_1	1.6\|134920\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134920-134949	30	NC_005703	Bacillus mycoides pBMY1 plasmid	1056-1085	8	0.733
NZ_CP014907_1	1.10\|135185\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	135185-135214	30	NC_031245	Bacillus phage SP-15, complete genome	166463-166492	8	0.733
NZ_CP014907_1	1.10\|135185\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	135185-135214	30	MK113949	Phage 5P_1, complete genome	29985-30014	8	0.733
NZ_CP014907_1	1.5\|134853\|31\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134853-134883	31	NZ_CP053574	Citrobacter sp. TSA-1 plasmid unnamed1, complete sequence	21078-21108	9	0.71
NZ_CP014907_1	1.5\|134853\|31\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134853-134883	31	NC_020123	Citrobacter freundii strain CFSTE plasmid pT-OXA-181, complete sequence	1326-1356	9	0.71
NZ_CP014907_1	1.7\|134986\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	134986-135015	30	MN694781	Marine virus AFVG_250M125, complete genome	37559-37588	9	0.7
NZ_CP014907_1	1.12\|135317\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	135317-135346	30	NC_019746	Gloeocapsa sp. PCC 7428 plasmid pGLO7428.01, complete sequence	182846-182875	9	0.7

1. spacer 1.2|134655|30|NZ_CP014907|CRISPRCasFinder,CRT matches to NC_021226 (Lactobacillus plantarum subsp. plantarum P-8 plasmid LBPp3, complete sequence) position: , mismatch: 0, identity: 1.0

ttgcgtatagcttcattagttgttaacgta	CRISPR spacer
ttgcgtatagcttcattagttgttaacgta	Protospacer
******************************

2. spacer 1.2|134655|30|NZ_CP014907|CRISPRCasFinder,CRT matches to NZ_CP021461 (Lactobacillus brevis strain ZLB004 plasmid p5, complete sequence) position: , mismatch: 0, identity: 1.0

ttgcgtatagcttcattagttgttaacgta	CRISPR spacer
ttgcgtatagcttcattagttgttaacgta	Protospacer
******************************

3. spacer 1.2|134655|30|NZ_CP014907|CRISPRCasFinder,CRT matches to NZ_CP017376 (Lactobacillus plantarum strain TMW 1.708 plasmid pL1708-2, complete sequence) position: , mismatch: 0, identity: 1.0

ttgcgtatagcttcattagttgttaacgta	CRISPR spacer
ttgcgtatagcttcattagttgttaacgta	Protospacer
******************************

4. spacer 1.2|134655|30|NZ_CP014907|CRISPRCasFinder,CRT matches to NZ_CP028270 (Pediococcus pentosaceus strain SRCM102740 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

ttgcgtatagcttcattagttgttaacgta	CRISPR spacer
ttgcgtatagcttcattagttgttaacgta	Protospacer
******************************

5. spacer 1.2|134655|30|NZ_CP014907|CRISPRCasFinder,CRT matches to NZ_CP028267 (Pediococcus pentosaceus strain SRCM102739 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

ttgcgtatagcttcattagttgttaacgta	CRISPR spacer
ttgcgtatagcttcattagttgttaacgta	Protospacer
******************************

6. spacer 1.2|134655|30|NZ_CP014907|CRISPRCasFinder,CRT matches to NZ_CP015919 (Pediococcus pentosaceus strain wikim20 plasmid pKPP01, complete sequence) position: , mismatch: 0, identity: 1.0

ttgcgtatagcttcattagttgttaacgta	CRISPR spacer
ttgcgtatagcttcattagttgttaacgta	Protospacer
******************************

7. spacer 1.2|134655|30|NZ_CP014907|CRISPRCasFinder,CRT matches to NZ_CP028265 (Pediococcus pentosaceus strain SRCM102738 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

ttgcgtatagcttcattagttgttaacgta	CRISPR spacer
ttgcgtatagcttcattagttgttaacgta	Protospacer
******************************

8. spacer 1.2|134655|30|NZ_CP014907|CRISPRCasFinder,CRT matches to NZ_CP019582 (Lactobacillus helveticus strain LH5 plasmid pCBTLH5_1, complete sequence) position: , mismatch: 0, identity: 1.0

ttgcgtatagcttcattagttgttaacgta	CRISPR spacer
ttgcgtatagcttcattagttgttaacgta	Protospacer
******************************

9. spacer 1.2|134655|30|NZ_CP014907|CRISPRCasFinder,CRT matches to NZ_CP023007 (Pediococcus pentosaceus strain SS1-3 plasmid pSS1301, complete sequence) position: , mismatch: 0, identity: 1.0

ttgcgtatagcttcattagttgttaacgta	CRISPR spacer
ttgcgtatagcttcattagttgttaacgta	Protospacer
******************************

10. spacer 1.2|134655|30|NZ_CP014907|CRISPRCasFinder,CRT matches to NZ_AP014681 (Lactobacillus hokkaidonensis JCM 18461 strain LOOC260 plasmid pLOOC260-1, complete sequence) position: , mismatch: 0, identity: 1.0

ttgcgtatagcttcattagttgttaacgta	CRISPR spacer
ttgcgtatagcttcattagttgttaacgta	Protospacer
******************************

11. spacer 1.2|134655|30|NZ_CP014907|CRISPRCasFinder,CRT matches to NZ_CP035308 (Lactobacillus helveticus strain IDCC3801 plasmid pHel23910, complete sequence) position: , mismatch: 0, identity: 1.0

ttgcgtatagcttcattagttgttaacgta	CRISPR spacer
ttgcgtatagcttcattagttgttaacgta	Protospacer
******************************

12. spacer 1.2|134655|30|NZ_CP014907|CRISPRCasFinder,CRT matches to NZ_CP031178 (Lactobacillus brevis strain UCCLB556 plasmid pUCCLB556_D, complete sequence) position: , mismatch: 0, identity: 1.0

ttgcgtatagcttcattagttgttaacgta	CRISPR spacer
ttgcgtatagcttcattagttgttaacgta	Protospacer
******************************

13. spacer 1.2|134655|30|NZ_CP014907|CRISPRCasFinder,CRT matches to NZ_CP021928 (Pediococcus pentosaceus strain SRCM100194 plasmid pPP194-2, complete sequence) position: , mismatch: 0, identity: 1.0

ttgcgtatagcttcattagttgttaacgta	CRISPR spacer
ttgcgtatagcttcattagttgttaacgta	Protospacer
******************************

14. spacer 1.2|134655|30|NZ_CP014907|CRISPRCasFinder,CRT matches to NZ_CP029967 (Lactobacillus curvatus strain ZJUNIT8 plasmid pnunamed1, complete sequence) position: , mismatch: 0, identity: 1.0

ttgcgtatagcttcattagttgttaacgta	CRISPR spacer
ttgcgtatagcttcattagttgttaacgta	Protospacer
******************************

15. spacer 1.2|134655|30|NZ_CP014907|CRISPRCasFinder,CRT matches to NZ_CP012188 (Lactobacillus paracasei strain CAUH35 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

ttgcgtatagcttcattagttgttaacgta	CRISPR spacer
ttgcgtatagcttcattagttgttaacgta	Protospacer
******************************

16. spacer 1.6|134920|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NC_014164 (Lactobacillus acidipiscis cryptic plasmid pLAC1, complete sequence, strain ACA-DC 1533) position: , mismatch: 0, identity: 1.0

gctcccacctgaattatgatttggtggctg	CRISPR spacer
gctcccacctgaattatgatttggtggctg	Protospacer
******************************

17. spacer 1.2|134655|30|NZ_CP014907|CRISPRCasFinder,CRT matches to NZ_CP044363 (Lactobacillus paracasei strain TD 062 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.967

ttgcgtatagcttcattagttgttaacgta	CRISPR spacer
ttgcgtatagcttcgttagttgttaacgta	Protospacer
**************.***************

18. spacer 1.2|134655|30|NZ_CP014907|CRISPRCasFinder,CRT matches to NZ_CP012190 (Lactobacillus paracasei strain CAUH35 plasmid unnamed3, complete sequence) position: , mismatch: 1, identity: 0.967

ttgcgtatagcttcattagttgttaacgta	CRISPR spacer
ttgcgtatagcttcgttagttgttaacgta	Protospacer
**************.***************

19. spacer 1.6|134920|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KF559315 (Lactobacillus sakei strain KCA311 plasmid pKCA3, complete sequence) position: , mismatch: 1, identity: 0.967

gctcccacctgaattatgatttggtggctg	CRISPR spacer
gttcccacctgaattatgatttggtggctg	Protospacer
*.****************************

20. spacer 1.6|134920|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NC_019353 (Leuconostoc mesenteroides subsp. mesenteroides plasmid pMBLR00, complete sequence) position: , mismatch: 1, identity: 0.967

gctcccacctgaattatgatttggtggctg	CRISPR spacer
gctcccacttgaattatgatttggtggctg	Protospacer
********.*********************

21. spacer 1.6|134920|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP037439 (Lactobacillus plantarum strain EM plasmid pEM10, complete sequence) position: , mismatch: 1, identity: 0.967

gctcccacctgaattatgatttggtggctg	CRISPR spacer
gctcccacttgaattatgatttggtggctg	Protospacer
********.*********************

22. spacer 1.6|134920|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP037439 (Lactobacillus plantarum strain EM plasmid pEM10, complete sequence) position: , mismatch: 1, identity: 0.967

gctcccacctgaattatgatttggtggctg	CRISPR spacer
gctcccacttgaattatgatttggtggctg	Protospacer
********.*********************

23. spacer 1.6|134920|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP037439 (Lactobacillus plantarum strain EM plasmid pEM10, complete sequence) position: , mismatch: 1, identity: 0.967

gctcccacctgaattatgatttggtggctg	CRISPR spacer
gctcccacttgaattatgatttggtggctg	Protospacer
********.*********************

24. spacer 1.6|134920|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LM651913 (Leuconostoc citreum strain NRRL B-1299 plasmid 1, complete sequence) position: , mismatch: 1, identity: 0.967

gctcccacctgaattatgatttggtggctg	CRISPR spacer
gctcccacttgaattatgatttggtggctg	Protospacer
********.*********************

25. spacer 1.6|134920|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NC_006399 (Lactobacillus plantarum BIFI-38 plasmid pPB1, complete sequence) position: , mismatch: 2, identity: 0.933

gctcccacctgaattatgatttggtggctg	CRISPR spacer
gctctcacctgaattatgatttagtggctg	Protospacer
****.*****************.*******

26. spacer 1.6|134920|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014880 (Lactobacillus backii strain TMW 1.1989 plasmid pL11989-7, complete sequence) position: , mismatch: 2, identity: 0.933

gctcccacctgaattatgatttggtggctg	CRISPR spacer
gctctcacctgaattatgatttagtggctg	Protospacer
****.*****************.*******

27. spacer 1.6|134920|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014880 (Lactobacillus backii strain TMW 1.1989 plasmid pL11989-7, complete sequence) position: , mismatch: 2, identity: 0.933

gctcccacctgaattatgatttggtggctg	CRISPR spacer
gctctcacctgaattatgatttagtggctg	Protospacer
****.*****************.*******

28. spacer 1.6|134920|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014906 (Lactobacillus backii strain TMW 1.2002 plasmid pL12002-7, complete sequence) position: , mismatch: 2, identity: 0.933

gctcccacctgaattatgatttggtggctg	CRISPR spacer
gctctcacctgaattatgatttagtggctg	Protospacer
****.*****************.*******

29. spacer 1.6|134920|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014906 (Lactobacillus backii strain TMW 1.2002 plasmid pL12002-7, complete sequence) position: , mismatch: 2, identity: 0.933

gctcccacctgaattatgatttggtggctg	CRISPR spacer
gctctcacctgaattatgatttagtggctg	Protospacer
****.*****************.*******

30. spacer 1.6|134920|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MK167463 (Lactobacillus plantarum strain PC518 plasmid pLP325, complete sequence) position: , mismatch: 3, identity: 0.9

gctcccacctgaattatgatttggtggctg	CRISPR spacer
actctcacctgaattatgatttagtggctg	Protospacer
.***.*****************.*******

31. spacer 1.6|134920|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NC_025165 (Lactobacillus hilgardii plasmid pLAB1000 or pHL1 sequence) position: , mismatch: 3, identity: 0.9

gctcccacctgaattatgatttggtggctg	CRISPR spacer
actctcacctgaattatgatttagtggctg	Protospacer
.***.*****************.*******

32. spacer 1.6|134920|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to KJ868088 (Lactobacillus pentosus strain F03 plasmid pF03-1, complete sequence) position: , mismatch: 3, identity: 0.9

gctcccacctgaattatgatttggtggctg	CRISPR spacer
gctctcacttgaattatgatttggtggcag	Protospacer
****.***.******************* *

33. spacer 1.7|134986|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033221 (Parasedimentitalea marina strain W43 plasmid pW43B, complete sequence) position: , mismatch: 5, identity: 0.833

cctactggaacaacaaatgggtcgaattca	CRISPR spacer
cctactggagcaacaattgggtcgaaaata	Protospacer
*********.****** *********  .*

34. spacer 1.13|135383|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to MK765551 (Tortoise microvirus 1 isolate 1_SP_22, complete genome) position: , mismatch: 6, identity: 0.8

ctggggacttgataacctcagcagtataag	CRISPR spacer
catcggacttgataacctcaacaggataat	Protospacer
*   ****************.*** ****

35. spacer 1.3|134721|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033036 (Agrobacterium fabrum strain 12D13 plasmid pAt12D13a, complete sequence) position: , mismatch: 7, identity: 0.767

cgtctccggactaaaattgctgtccgccca	CRISPR spacer
tgtctccggactaccattgctgtcgcccgg	Protospacer
.************  *********  ** .

36. spacer 1.3|134721|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033024 (Agrobacterium fabrum strain 1D132 plasmid pAt1D132a, complete sequence) position: , mismatch: 7, identity: 0.767

cgtctccggactaaaattgctgtccgccca	CRISPR spacer
tgtctccggactaccattgctgtcgcccgg	Protospacer
.************  *********  ** .

37. spacer 1.7|134986|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to MN693792 (Marine virus AFVG_250M943, complete genome) position: , mismatch: 7, identity: 0.767

cctactggaacaacaaatgggtcgaattca---	CRISPR spacer
actaatggaacaacaaattggtcgg---cagat	Protospacer
 *** ************* *****.   **

38. spacer 1.7|134986|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to MN694119 (Marine virus AFVG_250M974, complete genome) position: , mismatch: 7, identity: 0.767

cctactggaacaacaaatgggtcgaattca---	CRISPR spacer
actaatggaacaacaaattggtcgg---cagat	Protospacer
 *** ************* *****.   **

39. spacer 1.7|134986|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to MN694119 (Marine virus AFVG_250M974, complete genome) position: , mismatch: 7, identity: 0.767

cctactggaacaacaaatgggtcgaattca---	CRISPR spacer
actaatggaacaacaaattggtcgg---cagat	Protospacer
 *** ************* *****.   **

40. spacer 1.7|134986|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to MN694234 (Marine virus AFVG_250M972, complete genome) position: , mismatch: 7, identity: 0.767

cctactggaacaacaaatgggtcgaattca---	CRISPR spacer
actaatggaacaacaaattggtcgg---cagat	Protospacer
 *** ************* *****.   **

41. spacer 1.7|134986|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to MN692978 (Marine virus AFVG_117M13, complete genome) position: , mismatch: 7, identity: 0.767

cctactggaacaacaaatgggtcgaattca---	CRISPR spacer
actaatggaacaacaaattggtcgg---cagat	Protospacer
 *** ************* *****.   **

42. spacer 1.7|134986|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to MN694043 (Marine virus AFVG_250M973, complete genome) position: , mismatch: 7, identity: 0.767

cctactggaacaacaaatgggtcgaattca---	CRISPR spacer
actaatggaacaacaaattggtcgg---cagat	Protospacer
 *** ************* *****.   **

43. spacer 1.8|135052|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NC_018666 (Escherichia coli O104:H4 str. 2011C-3493 plasmid pAA-EA11, complete sequence) position: , mismatch: 7, identity: 0.767

taaggacattcatcatagattatttaaggg	CRISPR spacer
agaatatattcatcagagcttatttaaggg	Protospacer
 .*. *.******** ** ***********

44. spacer 1.8|135052|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NC_008460 (Escherichia coli plasmid pO86A1, complete sequence) position: , mismatch: 7, identity: 0.767

taaggacattcatcatagattatttaaggg	CRISPR spacer
agaatatattcatcagagcttatttaaggg	Protospacer
 .*. *.******** ** ***********

45. spacer 1.8|135052|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NC_018662 (Escherichia coli O104:H4 str. 2009EL-2071 plasmid pAA-09EL71, complete sequence) position: , mismatch: 7, identity: 0.767

taaggacattcatcatagattatttaaggg	CRISPR spacer
agaatatattcatcagagcttatttaaggg	Protospacer
 .*. *.******** ** ***********

46. spacer 1.8|135052|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022087 (Escherichia coli O104:H4 strain FDAARGOS_348 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

taaggacattcatcatagattatttaaggg	CRISPR spacer
agaatatattcatcagagcttatttaaggg	Protospacer
 .*. *.******** ** ***********

47. spacer 1.8|135052|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NC_022743 (Escherichia coli plasmid pHUSEC2011-2, complete sequence) position: , mismatch: 7, identity: 0.767

taaggacattcatcatagattatttaaggg	CRISPR spacer
agaatatattcatcagagcttatttaaggg	Protospacer
 .*. *.******** ** ***********

48. spacer 1.8|135052|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031904 (Escherichia coli O104:H4 strain FWSEC0009 plasmid unnamed19, complete sequence) position: , mismatch: 7, identity: 0.767

taaggacattcatcatagattatttaaggg	CRISPR spacer
agaatatattcatcagagcttatttaaggg	Protospacer
 .*. *.******** ** ***********

49. spacer 1.8|135052|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NC_018654 (Escherichia coli O104:H4 str. 2009EL-2050 plasmid pAA-09EL50, complete sequence) position: , mismatch: 7, identity: 0.767

taaggacattcatcatagattatttaaggg	CRISPR spacer
agaatatattcatcagagcttatttaaggg	Protospacer
 .*. *.******** ** ***********

50. spacer 1.8|135052|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023530 (Escherichia coli strain FDAARGOS_401 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

taaggacattcatcatagattatttaaggg	CRISPR spacer
agaatatattcatcagagcttatttaaggg	Protospacer
 .*. *.******** ** ***********

51. spacer 1.8|135052|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP041001 (Escherichia coli strain FDAARGOS_772 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

taaggacattcatcatagattatttaaggg	CRISPR spacer
agaatatattcatcagagcttatttaaggg	Protospacer
 .*. *.******** ** ***********

52. spacer 1.8|135052|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023533 (Escherichia coli strain FDAARGOS_403 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

taaggacattcatcatagattatttaaggg	CRISPR spacer
agaatatattcatcagagcttatttaaggg	Protospacer
 .*. *.******** ** ***********

53. spacer 1.8|135052|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP027392 (Escherichia coli O104:H4 strain FDAARGOS_349 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

taaggacattcatcatagattatttaaggg	CRISPR spacer
agaatatattcatcagagcttatttaaggg	Protospacer
 .*. *.******** ** ***********

54. spacer 1.6|134920|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP040674 (Exiguobacterium mexicanum strain A-EM plasmid punnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

gctcccacctgaattatgatttggtggctg	CRISPR spacer
gaacccacctcaattatgatttcgtgaaaa	Protospacer
*  ******* *********** ***.  .

55. spacer 1.6|134920|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NC_005703 (Bacillus mycoides pBMY1 plasmid) position: , mismatch: 8, identity: 0.733

gctcccacctgaattatgatttggtggctg	CRISPR spacer
gttcccacttgaattatgatttgtgtgaaa	Protospacer
*.******.**************   *  .

56. spacer 1.10|135185|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NC_031245 (Bacillus phage SP-15, complete genome) position: , mismatch: 8, identity: 0.733

gtatcttgtaaatgaattcaaattgattca	CRISPR spacer
gtatgttgtaaatgaagtcaaatggtgggg	Protospacer
**** *********** ****** *    .

57. spacer 1.10|135185|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to MK113949 (Phage 5P_1, complete genome) position: , mismatch: 8, identity: 0.733

gtatcttgtaaatgaattcaaattgattca	CRISPR spacer
atttcgtgtaaatgaattcaaattttgcga	Protospacer
.* ** ******************   . *

58. spacer 1.5|134853|31|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP053574 (Citrobacter sp. TSA-1 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.71

acaagctgatgaattaatgaaacgttcatta	CRISPR spacer
tggagccgatgaataaatgaaacgttttatc	Protospacer
  .***.******* ***********.  *

59. spacer 1.5|134853|31|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NC_020123 (Citrobacter freundii strain CFSTE plasmid pT-OXA-181, complete sequence) position: , mismatch: 9, identity: 0.71

acaagctgatgaattaatgaaacgttcatta	CRISPR spacer
tgaagctgatgatttactgaaacgtatggtg	Protospacer
  ********** *** ******** .. *.

60. spacer 1.7|134986|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to MN694781 (Marine virus AFVG_250M125, complete genome) position: , mismatch: 9, identity: 0.7

cctactggaacaacaaatgggtcgaattca	CRISPR spacer
aagactggtacaacaaatgggtcaaaaatg	Protospacer
   ***** **************.**  ..

61. spacer 1.12|135317|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NC_019746 (Gloeocapsa sp. PCC 7428 plasmid pGLO7428.01, complete sequence) position: , mismatch: 9, identity: 0.7

atcagcagtctttgagtatgctttagcata	CRISPR spacer
gctgtttgtcattgagtatgctttagcaca	Protospacer
.... . *** *****************.*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

435204 : 447905

Lactobacillus_phage(60.0%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_054646993.1\|435204_436563_+\|transposase	transposase	NA	NA	NA	NA
WP_004561985.1\|437512_438502_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	9.9e-59	40.5
WP_056997587.1\|438634_439993_+	SLC45 family MFS transporter	NA	NA	NA	NA
WP_054646973.1\|440008_442267_+	glycoside hydrolase family 65 protein	NA	NA	NA	NA
WP_054646974.1\|442323_443307_+	galactose mutarotase	NA	NA	NA	NA
WP_054646975.1\|443309_443981_+	beta-phosphoglucomutase	NA	NA	NA	NA
WP_002816285.1\|445546_445798_+\|transposase	IS3 family transposase	Q6J1X3	Lactobacillus_phage	9.2e-38	96.4
WP_180993523.1\|445851_446361_+\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	4.7e-89	98.2
WP_080952801.1\|446364_446694_+\|transposase	transposase	Q6J1X2	Lactobacillus_phage	1.5e-56	98.2
WP_103434005.1\|446835_447905_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	2.4e-34	33.2

DBSCAN-SWA_2

880352 : 946424

Lactobacillus_phage(65.91%)

portal,tail,capsid,terminase,integrase,protease,tRNA,head

attL 886429:886445|attR 919044:919060

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_054646685.1\|880352_883157_+\|tRNA	isoleucine--tRNA ligase	A0A1V0SJ93	Klosneuvirus	2.9e-87	26.9
WP_054646684.1\|883204_883405_+	cold shock domain-containing protein	NA	NA	NA	NA
WP_054646683.1\|883443_883989_+	NUDIX hydrolase	A0A291I9N0	Lactobacillus_phage	4.7e-10	30.5
WP_054646682.1\|883998_884289_+	hypothetical protein	NA	NA	NA	NA
WP_056997750.1\|884305_884995_+	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_054646681.1\|885018_886179_+	cysteine desulfurase	H7BUW1	unidentified_phage	4.0e-27	36.3
WP_054646680.1\|886178_886523_+	hypothetical protein	NA	NA	NA	NA
886429:886445	attL	NA	NA	NA	NA
WP_054646679.1\|886641_887766_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_056997749.1\|887853_888510_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_056997748.1\|888518_889205_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_054646677.1\|889214_891647_+	ATP-dependent RecD-like DNA helicase	A0A218KCE8	Bacillus_phage	4.9e-51	29.0
WP_054646676.1\|891695_892646_+	ribose-phosphate pyrophosphokinase	A0A1V0SHF7	Hokovirus	4.3e-35	32.3
WP_054646675.1\|892660_893656_+	aldo/keto reductase	NA	NA	NA	NA
WP_056997747.1\|893750_895439_-	ribonuclease J	NA	NA	NA	NA
WP_054646674.1\|895438_895657_-	DNA-dependent RNA polymerase auxiliary subunit epsilon family protein	NA	NA	NA	NA
WP_056997746.1\|895829_896309_+	hypothetical protein	NA	NA	NA	NA
WP_054646672.1\|896343_896904_-	peptide deformylase	E3SLL2	Synechococcus_phage	1.6e-13	41.4
WP_056997758.1\|897319_897997_+	hypothetical protein	NA	NA	NA	NA
WP_054646671.1\|897980_898280_+	UPF0223 family protein	NA	NA	NA	NA
WP_065866204.1\|898489_900328_+	translational GTPase TypA	E4ZFJ7	Streptococcus_phage	7.3e-23	24.3
WP_054646669.1\|900431_901613_+	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_054646668.1\|901887_902439_+	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	NA	NA	NA	NA
WP_054646667.1\|902453_902936_+	pantetheine-phosphate adenylyltransferase	NA	NA	NA	NA
WP_056997745.1\|902928_903978_+	PDZ domain-containing protein	NA	NA	NA	NA
WP_056997744.1\|904045_904723_+	helix-hairpin-helix domain-containing protein	NA	NA	NA	NA
WP_103422790.1\|904780_905266_+	ComE operon protein 2	A7KUY9	Bacillus_phage	3.5e-33	56.7
WP_083210459.1\|905400_906963_+	ComEC/Rec2 family competence protein	NA	NA	NA	NA
WP_065868680.1\|907017_908169_-\|integrase	tyrosine-type recombinase/integrase	A0A1C8E994	Bacillus_phage	4.6e-31	30.3
WP_065868681.1\|908242_908518_-	hypothetical protein	NA	NA	NA	NA
WP_065868682.1\|908877_909195_-	hypothetical protein	A0A222YZD3	Escherichia_phage	9.3e-11	37.6
WP_065868683.1\|909329_909980_-	LexA family transcriptional regulator	U3PIS7	Lactobacillus_phage	1.0e-32	39.6
WP_065868684.1\|910113_910371_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_156767908.1\|910548_910695_-	hypothetical protein	NA	NA	NA	NA
WP_054646893.1\|910746_911046_+	hypothetical protein	NA	NA	NA	NA
WP_054646894.1\|911047_911230_+	hypothetical protein	NA	NA	NA	NA
WP_065868685.1\|911360_911543_+	hypothetical protein	NA	NA	NA	NA
WP_065868686.1\|911546_911744_+	hypothetical protein	NA	NA	NA	NA
WP_065868687.1\|911754_912240_+	host-nuclease inhibitor Gam family protein	A0A0M7REK1	Lactobacillus_phage	1.3e-64	78.3
WP_065868688.1\|912249_912996_+	AAA family ATPase	A0A0M9JJ76	Lactobacillus_phage	8.6e-132	95.9
WP_191981847.1\|912937_914320_+	DEAD/DEAH box helicase family protein	A0A0M7RF77	Lactobacillus_phage	1.1e-225	84.2
WP_065868690.1\|914341_914896_+	DUF669 domain-containing protein	A0A0M9JJ55	Lactobacillus_phage	2.5e-91	88.2
WP_065868691.1\|914963_917291_+	DNA primase	A0A0M7RDT6	Lactobacillus_phage	0.0e+00	92.3
WP_065868692.1\|917676_917997_+	VRR-NUC domain-containing protein	A0A0M7RDN7	Lactobacillus_phage	1.2e-53	94.3
WP_065868693.1\|917993_918218_+	hypothetical protein	A0A0M7RE69	Lactobacillus_phage	5.0e-27	79.2
WP_065868694.1\|918207_918510_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_065868695.1\|918499_919123_+	hypothetical protein	NA	NA	NA	NA
919044:919060	attR	NA	NA	NA	NA
WP_083210460.1\|919082_919229_+	DUF1064 domain-containing protein	NA	NA	NA	NA
WP_065868696.1\|919395_919587_+	hypothetical protein	D6PSV3	Lactobacillus_phage	3.3e-19	71.4
WP_065868697.1\|919579_919975_+	hypothetical protein	C1KFE9	Lactobacillus_virus	1.9e-29	57.7
WP_065868698.1\|919979_920219_+	glutaredoxin-like protein NrdH	A0A0M7REK7	Lactobacillus_phage	5.3e-35	90.9
WP_065868699.1\|920223_921117_+	DNA adenine methylase	A0A2H4UUI2	Bodo_saltans_virus	3.9e-14	29.3
WP_065868700.1\|921315_921768_+	hypothetical protein	B4XYT9	Lactobacillus_phage	1.2e-16	35.9
WP_065868701.1\|922463_922967_+	HNH endonuclease	E9LUP7	Lactobacillus_phage	3.0e-35	48.4
WP_065868702.1\|923120_923597_+\|terminase	phage terminase small subunit P27 family	Q9AZM7	Lactococcus_phage	6.1e-22	40.0
WP_065868703.1\|923593_925507_+\|terminase	terminase large subunit	E9LUP9	Lactobacillus_phage	2.9e-163	45.1
WP_054646992.1\|925527_925719_+	DUF1056 family protein	E9LUQ0	Lactobacillus_phage	1.1e-06	48.4
WP_065868704.1\|925718_926858_+\|portal	phage portal protein	E9LUQ1	Lactobacillus_phage	2.0e-111	54.2
WP_065868705.1\|926844_927594_+\|protease	Clp protease ClpP	Q9AZS8	Lactococcus_phage	4.7e-45	50.0
WP_065868706.1\|927577_928813_+\|capsid	phage major capsid protein	E9LUQ3	Lactobacillus_phage	1.8e-110	52.6
WP_054646931.1\|928815_929151_+\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_065868707.1\|929143_929491_+\|head	phage head closure protein	Q6J1Y0	Lactobacillus_phage	4.9e-05	30.8
WP_065868708.1\|929493_929913_+	HK97 gp10 family phage protein	Q9AZL9	Lactococcus_phage	3.3e-11	39.4
WP_054646928.1\|929905_930301_+	DUF806 family protein	A0A2P0ZLF4	Lactobacillus_phage	6.8e-19	39.8
WP_065868709.1\|930301_931030_+	hypothetical protein	A0A2P0ZLH1	Lactobacillus_phage	4.5e-24	36.1
WP_065868710.1\|931004_931241_+	MucBP domain-containing protein	NA	NA	NA	NA
WP_065868711.1\|931307_931838_+	hypothetical protein	NA	NA	NA	NA
WP_065868712.1\|932077_936631_+	tape measure protein	A0A0M9JJ59	Lactobacillus_phage	1.5e-05	18.7
WP_065868713.1\|936630_937467_+\|tail	phage tail family protein	A0A0M7RF73	Lactobacillus_phage	1.3e-123	75.5
WP_065868714.1\|937478_938708_+	hypothetical protein	A0A0M9JJD9	Lactobacillus_phage	3.7e-79	39.5
WP_065868715.1\|938707_940459_+\|tail	phage tail protein	A0A0M7RDS2	Lactobacillus_phage	1.5e-219	62.3
WP_065868716.1\|940471_941005_+	hypothetical protein	A0A0M7RFE2	Lactobacillus_phage	4.7e-39	46.9
WP_065868717.1\|941007_941571_+	hypothetical protein	G4U401	Lactobacillus_phage	2.7e-13	92.7
WP_065868718.1\|941588_942026_+	hypothetical protein	NA	NA	NA	NA
WP_065868719.1\|942036_942513_+	hypothetical protein	NA	NA	NA	NA
WP_065868720.1\|942694_942988_+	hypothetical protein	A0A0M7RF42	Lactobacillus_phage	4.9e-30	64.9
WP_065868721.1\|942962_943214_+	hypothetical protein	A0A0M7REJ4	Lactobacillus_phage	1.5e-32	93.8
WP_065868722.1\|943229_944345_+	LysM peptidoglycan-binding domain-containing protein	A0A0M7RDM5	Lactobacillus_phage	8.9e-165	81.4
WP_065868723.1\|944517_945072_+	hypothetical protein	NA	NA	NA	NA
WP_065868724.1\|945073_945508_+	hypothetical protein	NA	NA	NA	NA
WP_056997536.1\|945848_946424_+	hypothetical protein	M1PSD2	Streptococcus_phage	4.4e-27	38.8

DBSCAN-SWA_3

1073795 : 1085112

Geobacillus_virus(14.29%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_054646161.1\|1073795_1074071_+	HU family DNA-binding protein	A0A0H3UZA0	Geobacillus_virus	4.4e-25	67.4
WP_054646162.1\|1074134_1075397_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_054646163.1\|1075518_1076730_+\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	1.2e-45	49.8
WP_065866218.1\|1076743_1078642_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2H4UUX5	Bodo_saltans_virus	9.5e-50	28.3
WP_054646165.1\|1078660_1079611_+	thymidylate synthase	A0A0N9SH48	Staphylococcus_phage	2.6e-117	60.5
WP_054646166.1\|1079620_1080112_+	dihydrofolate reductase	A0A0K2D000	Bacillus_phage	7.7e-20	32.3
WP_054646167.1\|1080124_1080346_+	YozE family protein	NA	NA	NA	NA
WP_054646168.1\|1080359_1081217_+	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_054646169.1\|1081222_1081984_+	ribonuclease HII	G9E3X7	Emiliania_huxleyi_virus	2.5e-25	39.5
WP_054646170.1\|1082018_1082894_+	DNA-protecting protein DprA	NA	NA	NA	NA
WP_054646171.1\|1082982_1085112_+	type I DNA topoisomerase	A0A1V0SB35	Catovirus	4.3e-91	34.8

DBSCAN-SWA_4

1375730 : 1385248

Streptococcus_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_054646431.1\|1375730_1376324_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	8.0e-56	53.8
WP_054646430.1\|1376376_1377315_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	8.3e-47	37.1
WP_054646429.1\|1377326_1378334_-	YvcK family protein	A1IMD5	Streptococcus_phage	1.5e-94	53.0
WP_065866267.1\|1378337_1379216_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.9e-08	30.5
WP_065868729.1\|1379306_1382171_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	8.6e-305	54.3
WP_054646426.1\|1382175_1384188_-	excinuclease ABC subunit UvrB	A0A2K9VDA5	Lactobacillus_phage	5.8e-05	24.8
WP_054646425.1\|1384318_1385248_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	1.3e-84	52.4

Anti-CRISPR protein detection

Acr_ID: NZ_CP014907.1|WP_065868686.1|911546_911744_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP014907.1|WP_065868686.1|911546_911744_+|hypothetical-protein

911546_911744_+

65 aa aa

880352-946424

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP014907_1	TypeII	1.9\|135118\|31\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	135118-135148	31	941534-941564	1
NZ_CP014907_1	TypeII	1.14\|135449\|30\|NZ_CP014907\|CRISPRCasFinder,CRT,PILER-CR	135449-135478	30	940266-940237	1

1. spacer 1.9|135118|31|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014907 position: 941534-941564, mismatch: 1

ccacttcttggtcgaattggaaaacaatcag	CRISPR spacer
ccacttattggtcgaattggaaaacaatcag	Protospacer
****** ************************

2. spacer 1.14|135449|30|NZ_CP014907|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014907 position: 940266-940237, mismatch: 1

gctgcgatcaaaacatcatagaattgcttc	CRISPR spacer
gctgcaatcaaaacatcatagaattgcttc	Protospacer
*****.************************

2. NZ_CP014911

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP014911_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP014911_1

5503-5659

Orphan

Consensus_repeat	Method
AATCCCTTGCTACGAGCGGAATTTCGAAAATCGAAAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP014911_1

>merge|NZ_CP014911|1|5503-5659|CRISPRCasFinder
AATCCCTTGCTACGAGCGGAATTTCGAAAATCGAAAGTCCGCATGACTTCGTTGAATCCCTTGCTACGAGCGGAATTTCGAAAATCGAAAGTCCGCATGACTTCGTTGACAATAGCTCTCAATCCCTTGCTACGAGCGGAATTTCGAAAATCGAAAG

>NZ_CP014911|1|1|5503-5659|CRISPRCasFinder
AATCCCTTGCTACGAGCGGAATTTCGAAAATCGAAAG	TCCGCATGACTTCGTTGAATCCCTTGCTACGAGCGGAATTTCGAAAATCGAAAGTCCGCATGACTTCGTTGACAATAGCTCTC
AATCCCTTGCTACGAGCGGAATTTCGAAAATCGAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP014911.1\|WP_001748272.1\|680_1037_-\|type-II-toxin-antitoxin-system-YafQ-family-toxin	unknown	unknown	gnl\|CDD\|379750
NZ_CP014911.1\|WP_156767911.1\|0_577_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|162098
NZ_CP014911.1\|WP_010620842.1\|1390_1978_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271192
NZ_CP014911.1\|WP_003590746.1\|4211_4454_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014911.1\|WP_021357815.1\|1986_2691_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP014911.1\|WP_062904640.1\|7774_8053_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014911.1\|WP_033615103.1\|3398_4208_+\|ParA-family-protein	unknown	unknown	gnl\|CDD\|224113
NZ_CP014911.1\|WP_010014831.1\|6594_6876_+\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	unknown	unknown	gnl\|CDD\|274102
NZ_CP014911.1\|WP_010012556.1\|7104_7785_+\|zeta-toxin-family-protein	unknown	unknown	gnl\|CDD\|226648
NZ_CP014911.1\|WP_010620892.1\|6922_7108_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP014911.1\|WP_010620850.1\|1036_1315_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl\|CDD\|376852

Protein	Function_ID	Function_description	E-value
NZ_CP014911.1\|WP_001748272.1\|680_1037_-\|type-II-toxin-antitoxin-system-YafQ-family-toxin	gnl\|CDD\|379750	pfam15738, YafQ_toxin, Bacterial toxin of type II toxin-antitoxin system, YafQ. YafQ is a family of bacterial toxin ribonucleases of type II toxin-antitoxin systems. The E.coli gene is expressed from the dinB operon. The cognate antitoxin for the E. coli protein is DinJ, in family RelB_antitoxin, pfam02604.	9.56513e-22
NZ_CP014911.1\|WP_156767911.1\|0_577_-\|MFS-transporter	gnl\|CDD\|162098	TIGR00900, multidrug_transporter, H+ Antiporter protein. [Transport and binding proteins, Cations and iron carrying compounds].	3.29807e-30
NZ_CP014911.1\|WP_010620842.1\|1390_1978_+\|site-specific-integrase	gnl\|CDD\|271192	cd01192, INT_C_like_3, Uncharacterized site-specific tyrosine recombinase, C-terminal catalytic domain. Tyrosine recombinase (integrase) belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain contains six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	8.28578e-73
NZ_CP014911.1\|WP_010014831.1\|6594_6876_+\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	gnl\|CDD\|274102	TIGR02384, Putative_antitoxin_RelB, addiction module antitoxin, RelB/DinJ family. Plasmids may be maintained stably in bacterial populations through the action of addiction modules, in which a toxin and antidote are encoded in a cassette on the plasmid. In any daughter cell that lacks the plasmid, the toxin persists and is lethal after the antidote protein is depleted. Toxin/antitoxin pairs are also found on main chromosomes, and likely represent selfish DNA. Sequences in the seed for this alignment all were found adjacent to toxin genes. The resulting model appears to describe a narrower set of proteins than pfam04221, although many in the scope of this model are not obviously paired with toxin proteins. Several toxin/antitoxin pairs may occur in a single species. [Cellular processes, Toxin production and resistance, Mobile and extrachromosomal element functions, Other].	6.2967e-11
NZ_CP014911.1\|WP_021357815.1\|1986_2691_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	3.2886e-16
NZ_CP014911.1\|WP_033615103.1\|3398_4208_+\|ParA-family-protein	gnl\|CDD\|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	5.29348e-35
NZ_CP014911.1\|WP_010012556.1\|7104_7785_+\|zeta-toxin-family-protein	gnl\|CDD\|226648	COG4185, COG4185, Uncharacterized protein conserved in bacteria [Function unknown].	8.5866e-39
NZ_CP014911.1\|WP_010620850.1\|1036_1315_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl\|CDD\|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	1.94572e-05

>NZ_CP014911.1|WP_003590746.1|4211_4454_+|hypothetical-protein
MANKFEKFSSTNNDYQVARDIQQKDALNEKLNWERKVKTSFSIQQKNIDRLDEMVNQLNAKSRSTLLDTIIENAYRDFQE
>NZ_CP014911.1|WP_033615103.1|3398_4208_+|ParA-family-protein
MQVISFMAIKGGVGKTTMAFQFAKFLQTQDQKVLMIDLDAQKSLTGTFENEHFNFSGKPTIADVLEKPSSGLIETQVQDNIAIIPSTSNLEEVADRLASKPNRELLLFMWFVKNAQELNQKYDYIIIDLPPAWNLLSKNGVAVADKIISPMEPSRFGYESHTKVLQSVGTLQDEVVDPVSGKSYITANVFFLGNRIKHNTNSSHEFLSALKHIDNVIGVIPEKELVNASMLAKEGILEYATQNDKLHEQEPFLKLLSDVFSEIQKQGND
>NZ_CP014911.1|WP_021357815.1|1986_2691_-|class-I-SAM-dependent-methyltransferase
MKSIWEMDAPIGLVFFFGPALIIGIMMLISGFNTVSAIMVLVLVLCGLKYMHTSIIGKYRIMKSIVNSIHLKKDSKILDAGCGHGAFMLQFNRKAANISEIIGIDIWSNKDQGSNSIAATQKIMENSNLADKVKLKTANILNMPFNDNEFDLIVSSLVLHNIKPFEKRKAALVNIARVQKQKGQLVIMDIGYETSKYVRILKDLGYQNVNIANTGYNGWWGTPMVPTFVITATK
>NZ_CP014911.1|WP_010620842.1|1390_1978_+|site-specific-integrase
MQQVVLPIKDSNVLKEVQDTLLNNFKAGRRNYTVFQVGKATLLRVSDVMRLKQTDIFNPDGSIKQNAFIHDRKTGKPNTLYLKPVQTELLLYRQWLLDHRLASEWLFPSIQHPERHITEKQFYKIMSKVGDLLGINYLGTHTMRKTGAYRVYTQSNYNIGLVMHLLNHSSEAMTLAYLGLDQASTESMLDQIDFG
>NZ_CP014911.1|WP_010620850.1|1036_1315_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MTLALTQSDFRANLKKYLDQVNDEDETVYIARSNSRAVAIVSQEKMDWLERALKAKEGSLEYAIARDQLIKRHVLPDDEIVESDDGYWGQFK
>NZ_CP014911.1|WP_001748272.1|680_1037_-|type-II-toxin-antitoxin-system-YafQ-family-toxin
MKKLRFKPRATFNADLKRLASLDKSIIDEVRAAIDLLLEQQQLPSEFEDHELNRRMSGYNEFHLRDTPKNKTPSETNDVLVVYTIDKDELVLIGIRVGSHDRLFPGQNRSKRYRKNDE
>NZ_CP014911.1|WP_156767911.1|0_577_-|MFS-transporter
MLVKDTVPLPTPLIEVVKNYLIIKKAATIWYLTKKTGSATVLSIATILGMLPMMILSPFVGPMVDRWNKKGLLIFPDVFAACFAIILSVSGTVFHVFPLWLIFISLLMQSCTQTFQMPTIQSVMPTMVPDKEITRMNGQLGMVQSANMIIAPALGAFLFAFIPIEYLILLDVLGAIIGICILTWVQQIPNNE
>NZ_CP014911.1|WP_010014831.1|6594_6876_+|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin
MAVKEKKRVQVQIDKELADNTEAVLSQLGLNPTTAINMFYKRIVADAALPFKPALSEAERANLSLLKATKETPVTEFKDAKEVADWLNDPDED
>NZ_CP014911.1|WP_010620892.1|6922_7108_+|hypothetical-protein
MKDTITINDFFEIAKETDLKDLLDKSLHEPDPEKRKVYDALYTYFLDKRQDEVIKRKDFVR
>NZ_CP014911.1|WP_010012556.1|7104_7785_+|zeta-toxin-family-protein
MIDKPQYIIVAGINGAGKSTLYDTFPILFDKTKRINADELLRQMGGDWHKDSDNLKAMKEEIKQLHYALDHQQSIHVETTLAGRGKAQLNLIDKAHKNGFEVTLLYVALRDENLAIQRVNERVQKGGHGVPVATIKKRYQQSKHNLPLVAFKSDKVMIYDNSEKFTSVYAREKGQVFKNDLRHFPWINQNITYPEKVQKQLQNFADQNPEVKPKNDPENKNDRPSY
>NZ_CP014911.1|WP_062904640.1|7774_8053_-|hypothetical-protein
MSNQYEKLVEQQARLKQKIEREDFKLRQSKYYENRQARKARSRRLIQKGALLEKYFQANNLSVEQTEELLKTFADYVNVHKPNKLKNDQPNN

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP014911_1	1.1\|5540\|83\|NZ_CP014911\|CRISPRCasFinder	5540-5622	83	NZ_CP012279	Pediococcus damnosus strain TMW 2.1533 plasmid pL21533-4, complete sequence	3450-3532	23	0.723
NZ_CP014911_1	1.1\|5540\|83\|NZ_CP014911\|CRISPRCasFinder	5540-5622	83	NZ_CP045730	Lactobacillus gastricus strain LG045 plasmid unnamed1, complete sequence	3542-3624	23	0.723
NZ_CP014911_1	1.1\|5540\|83\|NZ_CP014911\|CRISPRCasFinder	5540-5622	83	NZ_CP044413	Lactobacillus sp. JM1 plasmid unnamed1, complete sequence	16706-16788	23	0.723
NZ_CP014911_1	1.1\|5540\|83\|NZ_CP014911\|CRISPRCasFinder	5540-5622	83	NZ_CP014889	Lactobacillus backii strain TMW 1.1991 plasmid pL11991-8, complete sequence	6175-6257	24	0.711
NZ_CP014911_1	1.1\|5540\|83\|NZ_CP014911\|CRISPRCasFinder	5540-5622	83	NZ_CP014631	Lactobacillus backii strain TMW 1.1988 plasmid L11988-7, complete sequence	25032-25114	24	0.711
NZ_CP014911_1	1.1\|5540\|83\|NZ_CP014911\|CRISPRCasFinder	5540-5622	83	NZ_CP029972	Lactobacillus kefiri strain DH5 plasmid pDH5, complete sequence	20634-20716	24	0.711
NZ_CP014911_1	1.1\|5540\|83\|NZ_CP014911\|CRISPRCasFinder	5540-5622	83	NZ_CP029972	Lactobacillus kefiri strain DH5 plasmid pDH5, complete sequence	20688-20770	24	0.711
NZ_CP014911_1	1.1\|5540\|83\|NZ_CP014911\|CRISPRCasFinder	5540-5622	83	NC_011352	Lactobacillus paracasei plasmid plca36, complete sequence	462-544	24	0.711
NZ_CP014911_1	1.1\|5540\|83\|NZ_CP014911\|CRISPRCasFinder	5540-5622	83	NZ_CP031183	Lactobacillus brevis strain UCCLB95 plasmid pUCCLB95_A, complete sequence	816-898	24	0.711
NZ_CP014911_1	1.1\|5540\|83\|NZ_CP014911\|CRISPRCasFinder	5540-5622	83	NZ_CP044414	Lactobacillus sp. JM1 plasmid unnamed2, complete sequence	25960-26042	24	0.711
NZ_CP014911_1	1.1\|5540\|83\|NZ_CP014911\|CRISPRCasFinder	5540-5622	83	NZ_CP008839	Lactobacillus gasseri DSM 14869 plasmid pEB01-1, complete sequence	37234-37316	24	0.711
NZ_CP014911_1	1.1\|5540\|83\|NZ_CP014911\|CRISPRCasFinder	5540-5622	83	NZ_CP012287	Pediococcus damnosus strain TMW 2.1534 plasmid pL21534-4, complete sequence	30312-30394	35	0.578
NZ_CP014911_1	1.1\|5540\|83\|NZ_CP014911\|CRISPRCasFinder	5540-5622	83	NZ_CP012274	Pediococcus damnosus strain TMW 2.1532 plasmid pL21532-5, complete sequence	31520-31602	35	0.578

1. spacer 1.1|5540|83|NZ_CP014911|CRISPRCasFinder matches to NZ_CP012279 (Pediococcus damnosus strain TMW 2.1533 plasmid pL21533-4, complete sequence) position: , mismatch: 23, identity: 0.723

tccgcatgacttcgttgaatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	CRISPR spacer
tccgcatgacttcgttgaatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	Protospacer
************************************************************

2. spacer 1.1|5540|83|NZ_CP014911|CRISPRCasFinder matches to NZ_CP045730 (Lactobacillus gastricus strain LG045 plasmid unnamed1, complete sequence) position: , mismatch: 23, identity: 0.723

tccgcatgacttcgttgaatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	CRISPR spacer
tccgcatgacttcgttgaatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	Protospacer
************************************************************

3. spacer 1.1|5540|83|NZ_CP014911|CRISPRCasFinder matches to NZ_CP044413 (Lactobacillus sp. JM1 plasmid unnamed1, complete sequence) position: , mismatch: 23, identity: 0.723

tccgcatgacttcgttgaatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	CRISPR spacer
tccgcatgacttcgttgaatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	Protospacer
************************************************************

4. spacer 1.1|5540|83|NZ_CP014911|CRISPRCasFinder matches to NZ_CP014889 (Lactobacillus backii strain TMW 1.1991 plasmid pL11991-8, complete sequence) position: , mismatch: 24, identity: 0.711

tccgcatgacttcgttgaatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	CRISPR spacer
tccgcatgacttcgttggatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	Protospacer
*****************.******************************************

5. spacer 1.1|5540|83|NZ_CP014911|CRISPRCasFinder matches to NZ_CP014631 (Lactobacillus backii strain TMW 1.1988 plasmid L11988-7, complete sequence) position: , mismatch: 24, identity: 0.711

tccgcatgacttcgttgaatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	CRISPR spacer
tccgcatgacttcgttggatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	Protospacer
*****************.******************************************

6. spacer 1.1|5540|83|NZ_CP014911|CRISPRCasFinder matches to NZ_CP029972 (Lactobacillus kefiri strain DH5 plasmid pDH5, complete sequence) position: , mismatch: 24, identity: 0.711

tccgcatgacttcgttgaatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	CRISPR spacer
tccgcatgacttcgttggatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	Protospacer
*****************.******************************************

7. spacer 1.1|5540|83|NZ_CP014911|CRISPRCasFinder matches to NZ_CP029972 (Lactobacillus kefiri strain DH5 plasmid pDH5, complete sequence) position: , mismatch: 24, identity: 0.711

tccgcatgacttcgttgaatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	CRISPR spacer
tccgcatgacttcgttggatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	Protospacer
*****************.******************************************

8. spacer 1.1|5540|83|NZ_CP014911|CRISPRCasFinder matches to NC_011352 (Lactobacillus paracasei plasmid plca36, complete sequence) position: , mismatch: 24, identity: 0.711

tccgcatgacttcgttgaatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	CRISPR spacer
tccgcatgacttcgttgaaacccttgctacgagcggaatttcgaaaatcgaaagtccgca	Protospacer
******************* ****************************************

9. spacer 1.1|5540|83|NZ_CP014911|CRISPRCasFinder matches to NZ_CP031183 (Lactobacillus brevis strain UCCLB95 plasmid pUCCLB95_A, complete sequence) position: , mismatch: 24, identity: 0.711

tccgcatgacttcgttgaatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	CRISPR spacer
tccgcatgacttcgttggatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	Protospacer
*****************.******************************************

10. spacer 1.1|5540|83|NZ_CP014911|CRISPRCasFinder matches to NZ_CP044414 (Lactobacillus sp. JM1 plasmid unnamed2, complete sequence) position: , mismatch: 24, identity: 0.711

tccgcatgacttcgttgaatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	CRISPR spacer
tccgcatgacttcgttgaaacccttgctacgagcggaatttcgaaaatcgaaagtccgca	Protospacer
******************* ****************************************

11. spacer 1.1|5540|83|NZ_CP014911|CRISPRCasFinder matches to NZ_CP008839 (Lactobacillus gasseri DSM 14869 plasmid pEB01-1, complete sequence) position: , mismatch: 24, identity: 0.711

tccgcatgacttcgttgaatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	CRISPR spacer
tccgcatgacttcgttgaaacccttgctacgagcggaatttcgaaaatcgaaagtccgca	Protospacer
******************* ****************************************

12. spacer 1.1|5540|83|NZ_CP014911|CRISPRCasFinder matches to NZ_CP012287 (Pediococcus damnosus strain TMW 2.1534 plasmid pL21534-4, complete sequence) position: , mismatch: 35, identity: 0.578

tccgcatgacttcgttgaatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	CRISPR spacer
tggacaagaaacgccgaaatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	Protospacer
*  .** **  .  . .*******************************************

13. spacer 1.1|5540|83|NZ_CP014911|CRISPRCasFinder matches to NZ_CP012274 (Pediococcus damnosus strain TMW 2.1532 plasmid pL21532-5, complete sequence) position: , mismatch: 35, identity: 0.578

tccgcatgacttcgttgaatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	CRISPR spacer
tggacaagaaacgccgaaatcccttgctacgagcggaatttcgaaaatcgaaagtccgca	Protospacer
*  .** **  .  . .*******************************************

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP014907

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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2. NZ_CP014911

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection