CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP007220	Mycobacteroides chelonae CCUG 47445 chromosome, complete genome	1 crisprs	cas3,csa3,DinG,DEDDh,cas4,WYL	0	0	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP007220_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007220_1

4393245-4393339

Orphan

Consensus_repeat	Method
CCGCCCGGTCCGAACAGCGGGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007220_1

>merge|NZ_CP007220|1|4393245-4393339|CRISPRCasFinder
CCGCCCGGTCCGAACAGCGGGCGCTGGGTGTACACACCGGCCGCGTTGGGTGAACCGTCACCGATGATCAACCCACCCGGTCCGAACAGCGGGCG

>NZ_CP007220|1|1|4393245-4393339|CRISPRCasFinder
CCGCCCGGTCCGAACAGCGGGCG	CTGGGTGTACACACCGGCCGCGTTGGGTGAACCGTCACCGATGATCAAC
CCACCCGGTCCGAACAGCGGGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007220.1\|WP_046254976.1\|4389649_4390561_-\|cation-transporter	unknown	unknown	gnl\|CDD\|224151
NZ_CP007220.1\|WP_046254973.1\|4384502_4386083_+\|Na+/H+-antiporter	unknown	unknown	gnl\|CDD\|129911
NZ_CP007220.1\|WP_046256056.1\|4403616_4404276_+\|membrane-protein	unknown	unknown	gnl\|CDD\|182775
NZ_CP007220.1\|WP_081252305.1\|4386087_4386750_-\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|239527
NZ_CP007220.1\|WP_046254979.1\|4404849_4405278_-\|acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|223894
NZ_CP007220.1\|WP_075874142.1\|4384124_4384442_-\|UBP-type-zinc-finger-domain-containing-protein	unknown	unknown	gnl\|CDD\|366940
NZ_CP007220.1\|WP_046254978.1\|4404378_4404834_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007220.1\|WP_046256054.1\|4401850_4402318_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007220.1\|WP_046254974.1\|4388190_4388862_+\|peptidase-M50	unknown	unknown	gnl\|CDD\|366301
NZ_CP007220.1\|WP_030096232.1\|4390702_4391131_-\|DUF3151-domain-containing-protein	unknown	unknown	gnl\|CDD\|378646
NZ_CP007220.1\|WP_046254975.1\|4388872_4389637_+\|site-2-protease-family-protein	unknown	unknown	gnl\|CDD\|100079
NZ_CP007220.1\|WP_030096231.1\|4391234_4392014_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007220.1\|WP_162269725.1\|4406408_4407044_-\|RNA-methyltransferase	unknown	unknown	gnl\|CDD\|349969
NZ_CP007220.1\|WP_046254984.1\|4408554_4409346_-\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223377
NZ_CP007220.1\|WP_030096236.1\|4386746_4388042_-\|adenylosuccinate-synthase	unknown	unknown	gnl\|CDD\|234904
NZ_CP007220.1\|WP_046254980.1\|4405279_4406377_-\|fructose-bisphosphate-aldolase	unknown	unknown	gnl\|CDD\|227170
NZ_CP007220.1\|WP_046254983.1\|4407995_4408568_-\|orotate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234771
NZ_CP007220.1\|WP_046254972.1\|4382688_4384053_-\|formate-dependent-phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|236454
NZ_CP007220.1\|WP_046256055.1\|4402438_4403482_-\|class-II-fructose-bisphosphate-aldolase	unknown	unknown	gnl\|CDD\|236406
NZ_CP007220.1\|WP_046254982.1\|4407084_4407999_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP007220.1\|WP_046254976.1\|4389649_4390561_-\|cation-transporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	9.33765e-89
NZ_CP007220.1\|WP_046254973.1\|4384502_4386083_+\|Na+/H+-antiporter	gnl\|CDD\|129911	TIGR00831, Putative_Na+/H+_exchanger_Rv2287/MT2345/Mb2309., Na+/H+ antiporter, bacterial form. The Monovalent Cation:Proton Antiporter-1 (CPA1) Family (TC 2.A.36) The CPA1 family is a large family of proteins derived from Gram-positive and Gram-negative bacteria, blue green bacteria, yeast, plants and animals. Transporters from eukaryotes have been functionally characterized, and all of these catalyze Na+:H+ exchange. Their primary physiological functions may be in (1) cytoplasmic pH regulation, extruding the H+ generated during metabolism, and (2) salt tolerance (in plants), due to Na+ uptake into vacuoles. This model is specific for the bacterial members of this family. [Transport and binding proteins, Cations and iron carrying compounds].	9.47232e-80
NZ_CP007220.1\|WP_046256056.1\|4403616_4404276_+\|membrane-protein	gnl\|CDD\|182775	PRK10847, PRK10847, DedA family protein.	5.90103e-48
NZ_CP007220.1\|WP_081252305.1\|4386087_4386750_-\|PaaI-family-thioesterase	gnl\|CDD\|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	2.87019e-16
NZ_CP007220.1\|WP_046254979.1\|4404849_4405278_-\|acyl-CoA-thioesterase	gnl\|CDD\|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	1.0261e-34
NZ_CP007220.1\|WP_075874142.1\|4384124_4384442_-\|UBP-type-zinc-finger-domain-containing-protein	gnl\|CDD\|366940	pfam02148, zf-UBP, Zn-finger in ubiquitin-hydrolases and other protein.	5.11637e-07
NZ_CP007220.1\|WP_162269725.1\|4406408_4407044_-\|RNA-methyltransferase	gnl\|CDD\|349969	cd18096, SpoU-like, SAM-dependent rRNA or tRNA methylase related to SpoU. RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.	9.42193e-59
NZ_CP007220.1\|WP_046254974.1\|4388190_4388862_+\|peptidase-M50	gnl\|CDD\|366301	pfam00781, DAGK_cat, Diacylglycerol kinase catalytic domain. Diacylglycerol (DAG) is a second messenger that acts as a protein kinase C activator. The catalytic domain is assumed from the finding of bacterial homologs. YegS is the Escherichia coli protein in this family whose crystal structure reveals an active site in the inter-domain cleft formed by four conserved sequence motifs, revealing a novel metal-binding site. The residues of this site are conserved across the family.	0.0063566
NZ_CP007220.1\|WP_030096232.1\|4390702_4391131_-\|DUF3151-domain-containing-protein	gnl\|CDD\|378646	pfam11349, DUF3151, Protein of unknown function (DUF3151). This family of proteins with unknown function appears to be restricted to Actinobacteria.	2.69834e-67
NZ_CP007220.1\|WP_046254975.1\|4388872_4389637_+\|site-2-protease-family-protein	gnl\|CDD\|100079	cd06158, S2P-M50_like_1, Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the S2P/M50 family of RIP proteases use proteolytic activity within the membrane to transfer information across membranes to integrate gene expression with physiologic stresses occurring in another cellular compartment. In eukaryotic cells they regulate such processes as sterol and lipid metabolism, and endoplasmic reticulum stress responses. In prokaryotes they regulate such processes as sporulation, cell division, stress response, and cell differentiation. This group includes bacterial, eukaryotic, and Archaeal S2P/M50s homologs with a minimal core protein and no PDZ domains.	4.74351e-43
NZ_CP007220.1\|WP_046254984.1\|4408554_4409346_-\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|223377	COG0300, DltE, Short-chain dehydrogenases of various substrate specificities [General function prediction only].	1.18159e-71
NZ_CP007220.1\|WP_030096236.1\|4386746_4388042_-\|adenylosuccinate-synthase	gnl\|CDD\|234904	PRK01117, PRK01117, adenylosuccinate synthetase; Provisional.	0
NZ_CP007220.1\|WP_046254980.1\|4405279_4406377_-\|fructose-bisphosphate-aldolase	gnl\|CDD\|227170	COG4833, COG4833, Predicted glycosyl hydrolase [Carbohydrate transport and metabolism].	1.3864e-131
NZ_CP007220.1\|WP_046254972.1\|4382688_4384053_-\|formate-dependent-phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|236454	PRK09288, purT, formate-dependent phosphoribosylglycinamide formyltransferase.	1.41405e-159
NZ_CP007220.1\|WP_046256055.1\|4402438_4403482_-\|class-II-fructose-bisphosphate-aldolase	gnl\|CDD\|236406	PRK09197, PRK09197, fructose-bisphosphate aldolase; Provisional.	0
NZ_CP007220.1\|WP_046254983.1\|4407995_4408568_-\|orotate-phosphoribosyltransferase	gnl\|CDD\|234771	PRK00455, pyrE, orotate phosphoribosyltransferase; Validated.	7.70056e-63

>NZ_CP007220.1|WP_030096231.1|4391234_4392014_+|hypothetical-protein
MANPTGGNSEAKPDSQGDEPVDSAEQPEGAAHTPEISDTADTGPVPPLDDAQTVVMPPAKPDVPRYTAPGFDANKTEMIAPVGDDPKTEMIQPLATQARPKIATPETIAPRKEEKRSWGWVIALTLVVAALAAVIVLAAVIISRTSAPKASQEELVRNSIQNYDNAIQTGNLAALRAITCGETRDGYVRYPDAEWSQTYQKVAAAKQYPVVASIDEVVVNGEHAEANVTSFMAFAPQTRSSRSFDLQFRDKEWKICQSD
>NZ_CP007220.1|WP_030096232.1|4390702_4391131_-|DUF3151-domain-containing-protein
MSPMHDLLGPEPVLLPGDAEAESALIEGRDPAAVAAAYPSASIAWAELAENALDGDGSVGSIITAYAFARTGYHRGLDQLRRNGWKGFGPVPYSHEPNRGFLRAVAALARAAQLIGESHEFARCCDLLDDCDPAARPALLTS
>NZ_CP007220.1|WP_046254976.1|4389649_4390561_-|cation-transporter
MGAGHDHGHVGNPADARVGRMWVSLGIVGSFFVLELVVALLINSLALLADAGHMLTDLVGLIMGLSAILLARRGSTSAARTYGWHRAEVLTAIVNAALLTGIAAFVMYEAVERLTGGAPPEVPGLPMMVVALAGLAANVVVIWLLRSHAESSLAVRGAYMEVLADAVGSVGVLVAAIITLTTGWRYADIVVGVLISLWILPRAFSLARAALRILTETSPKHIDVDELRAALLAVDGVSSVHDLHVWTLVPGKDMATAHLTSTADAAQVLAAARSVLAERGLPHATIQVEPPEAQEHCEEHANW
>NZ_CP007220.1|WP_046254975.1|4388872_4389637_+|site-2-protease-family-protein
MKTSQSVRPSPVFLALVALTVAGAVLAWLGGNSTEPLARGGVFVFVFTGWVVSLCLHEFGHAYTAWRFGDTQARGYLTLNPLQYTDPVLSMVLPLVFIALGGIGLPGGAVYVHTAGMTNRQRTQVSLAGPSANAALAVLILGTTALFADRDHVVFWAAMAYLGFLQVTAVVLNLLPVPGLDGYGALEPHLSPKTQRTLANAKTFGFLILFVLLMSPPINRAFFDAVYWIVASLGVDPDLSRIGGWLFRFWGKLL
>NZ_CP007220.1|WP_046254974.1|4388190_4388862_+|peptidase-M50
MSTPSVTETAAARVLLFGTRRLPRILRDLPVDRVEGSDAVRTLLDALPDGTLRLIVVGGDGDLGQVLTRLMRAERLDVELGFVPDRRSRARRTYRIGIGAARRARTGRAHRVPLIRDDTGTALAGRASWQGTDGEAVTGEATVDDTLLFEGIAAVDIEPIEALPGLRAGVRGRARLLPRRWVTGRAAQLGTDGAVVVRDGVAGARPVTRSTFYRHQQGWLLVR
>NZ_CP007220.1|WP_030096236.1|4386746_4388042_-|adenylosuccinate-synthase
MPAIVLIGAQWGDEGKGKATDLLGGSVQWVVRYQGGNNAGHTVVLPNGENFALHLIPSGILTPGVTNVIGNGVVVDPGVLLTELAGLEQRGIDTSGLILSADAHLLMPYHVAIDKVTERYLGSKKIGTTGRGIGPCYQDKVARIGIRVADVLDEESLRQKVHAALEFKNQVLVKIYNRKALDPDQVVDGVLEQAEGFKHRIADARLELNQALERGETVLLEGSQGTLLDVDHGTYPFVTSSNPTAGGASVGSGIGPTRITTVLGILKAYTTRVGSGPFPTELFDEHGAYLAKTGGEVGVTTGRARRCGWFDAVIARYATRVNGITDYFLTKLDVLSSLQTVPICVGYEVDGKRTNEMPMTQSEIYRATPVYEELPGWWEDISTAREFSDLPAKAQDYVLRLEELAGAPMSCIGVGPGRDQTIVRRDILSKS
>NZ_CP007220.1|WP_081252305.1|4386087_4386750_-|PaaI-family-thioesterase
MTADGDRLAALHEEMNRAIREIRGGGFPQYSPSSVGPGFGRFLTAMRRLQDLAVSADMDDPRWDEAADLTEKLVELMDPYQAPEGVGPANRVADEPANGHLLLPPWFIDKAGPDGIEAHGDFPRFYLGGNGAVHGGILPLLFDHLFGMTVIMAGRTISRTAFLHVNYRQVVPVGVPLTASSRIDEVDRRKAFVSAELYDAAGTVLADANGLMVQLLPGQP
>NZ_CP007220.1|WP_046254973.1|4384502_4386083_+|Na+/H+-antiporter
MNVSLLAVLTAALVLAAISRRFGLPTPLVLVVAGLAATAIPGLPSIEMDPDLVLFVILPPLLYTTALESSYVNLRKNVRAVSSLAVVLPLVTTVAVGFVAFYAVPELPLAGAMVLGAIVAPPDAVSATAIGRRLGLPRNIMTLLGGESLLNDATALTAYRVAIAAAIGLGATVADGLKIFALAAVGGVLVGVVIGKLVNIIRCKLDDPLSESAIGLVVPFFAYLLAEEIHGSGVIAVVVAGLMLGHRSVHAGYATRLQDDAVWKAVQLLLESFAFLLIGLQLPKVIEGLRGLSFQTIALSSIAVLATVIVVRIVFVFAFAYMRPPGQRPSARGVFVVAWAGMRGVVSLAMAFAVPLSTVTGEPLPGHPHIVFLTFVVVVGTLLLHGLTLPWVIRVLGVQSDDERKDALAEAAAQDKAARAAADRLEELLDDNDGIEDTNVRSRAAEILRHWNTRRRNAAWERLGRSDEDAGESPMAAFRNLRLEMLEKEREVFIAERDAGNIDDEVLRTVLRGLDLEEATMNQADR
>NZ_CP007220.1|WP_075874142.1|4384124_4384442_-|UBP-type-zinc-finger-domain-containing-protein
MKRLFRRGSAAPASTPGQGPCPELVAATGPDPEARTPGRCEDCAALGEQVWAHLRMCLECGRVSCCDSSPHQHATAHFHASGHPVMRSHEPGEDWRWCYIHSTLG
>NZ_CP007220.1|WP_046254972.1|4382688_4384053_-|formate-dependent-phosphoribosylglycinamide-formyltransferase
MVVTQEGSPPSEQGSTASTDTVEPGPAETAPVTEDAIRATNGAKVPKSAKAAKPTVETAASAGDVPEPAAPNRTTVMLLGSGELARELAISFQRLGAEVVVVDTGTPGPAQDAADRSMRASIGESETLFELVEKERPRFVVPLVETASVDALEKLADGKVTQVIPTAKAVRLAGDREAMRRMAAEELGLPTPAYWFANSVEELHKILETAGFPVVVRPVSAAYGQGESVVLRESDAEPAWDQAVAANIGDIRRVLVETVVEIDYEITLLTVRTAGVGGATRLYFCEPIAHRQSGTDAMQMWQPQPLSQAALELARSIAARAVNALGGHGVYGVELFVRGDEVYFCDVSARPYDSGLVTVRSQRLSEFDMHARAVLGVPIDTILVSPAAAELVYGDGQGPSPRQLDEALQIPESDLRVFGHSEIHRRRRVGLALATAPNTALAMSRAHQVARHLR
>NZ_CP007220.1|WP_046256054.1|4401850_4402318_-|hypothetical-protein
MVLERSAGVAALVALVLAVTALVLVLSRGRAPAQADYTAAQRADAKTQACASASLVRNAVMLNTNRALPENAGVVGTLASAANARIALFNGGQYLLARLDPATPPDLAASIRDFGNALMDVGAAAIAETPNTDPKQAQRLSKADELSKHIVELCK
>NZ_CP007220.1|WP_046256055.1|4402438_4403482_-|class-II-fructose-bisphosphate-aldolase
MPIATPEVYAEMLDRAKEHSFAFPAINCTSSETINAAIKGFADAGSDGIIQFSTGGAEFGSGLGIKDMVTGAVALAEFAHVVAAKYGITVALHTDHCPKDKLDSFVRPLIAISQERVVAGQNPLFQSHMWDGSAVPIGENLEIAQELLAATAKAHIILEVEIGVVGGEEDGVEAEINEKLYTSSEDFEKTVEALGVGENGRYLLAATFGNVHGVYKPGNVKLKPEVLAEGQRVASAKLGLAEGSKPFDFVFHGGSGSLKSEIEDSLRYGVVKMNVDTDTQYAFTRPIAGHMFANYDGVLKIDGEVGNKKTYDPRSYLKKAEANMTERVIEACNDLKSAGRSVSAGLA
>NZ_CP007220.1|WP_046256056.1|4403616_4404276_+|membrane-protein
MPDFLDPVKLLGHFGTLALLGLLVVIFVESGVLFPVLPGDSLLFVAGMLAAGTAAAAADGAPQANFQLWQLLVFIPIAAILGGQVGYWIGRGIGTSMFKPDARFLKQKYLEEAHAFFEKRGPFAIVIARFVPIVRTLAPITAGAAKMSYPIFALYNILGAVVWGVGLTLLGYWLGQFEIIQKLLEPIFILIVLVSVAPMFFEWMRRRKAAKQPEAAPEA
>NZ_CP007220.1|WP_046254978.1|4404378_4404834_+|hypothetical-protein
MGKINSYLTAIALMGWGFAAPAGAEPAPADVAGASEAVQTYINATNNVDVPLMRATVCGRLAAATSAGTDEQVRQVMQSQRDRIGLAHIEVLRPVELGSPPGQVDLLAQLTSEHHPQDPGGNGINLVYHTEKVDGSWKVCHARNEGHLDEP
>NZ_CP007220.1|WP_046254979.1|4404849_4405278_-|acyl-CoA-thioesterase
MAREDFSFFHPLRVRWAEVDMQGVVFNAHYLAFFDAALTEYWAALTGARNAEGDGIFEHMYVVRSVIDYHAPARFDDVLDIGVRIARMGTASMTCHFEIHRGGEHLITGETVYVHAIDGTSTPFPDDFRGKVAAFETTPVRA
>NZ_CP007220.1|WP_046254980.1|4405279_4406377_-|fructose-bisphosphate-aldolase
MDVLWANRASSAEAAITARHFSPLWHLPRMRLGIVTWPPAPGATWFKNWHYWWQAHLQDCLIDAQLRDPRPDRLKYIADMQRAHRFRNVFMWTNQYYDDMAWLALAMQRASELLGLERPRALNRLRQQFLDAWMPQYGGGIPWRKQDKFFNTPANGPAAIVLARTGRVWRAEVMSDWIDNTLVDPESHLVIDGIQEDGTLERATYTYCQGVVLGLETELAVRTGESRHAERVHRLVHAVKDHMTAEGVIRGSGGGDGGLFNGILARYLALVVTTLPENSPRDTDARAVARDILLTSAEAAWTNRLTVEDLPLFGADWTRTAALPTVQSQASQFIAGAVNPSKVPERDLSVQLSGWMLLEAAHVVA
>NZ_CP007220.1|WP_162269725.1|4406408_4407044_-|RNA-methyltransferase
MWGATGNGVGPWADERGLPLPTDPRYDPELLRDGDARNVVDAYRYWRREAIVADIDTRRHRLHIAIENFENDANIGTVVRTANAFAVHTVHIVGRRRWNRRGAMVTDRYQRLMHHDSTEQLLEYAKLTGLTVVAVDNVPGSVPLETAVLPADCLMVFGQEGPGVTDVSKVGAVMTVSIAQFGSTRSINAGVAAGVAMHAWIRQHADPTKAW
>NZ_CP007220.1|WP_046254982.1|4407084_4407999_-|hypothetical-protein
MTFRRALAALVAGVLVLTGCSKDLEKELVYGAPTAKVGETQSLLGWNLSVANLRFQNGYVLVDITGAAAKPEEKPAAAGDLRFGLYGSLAHPLEVPALGSCRDVADLSVHPLTATPSAGAATGLTGTVCLGPMQNQSAVRGVYAYSAKDRIAGSTVAYPVAYPMGLLPTPQNDSGLVIVTKSMEAWRASGQQISQVDLGDPNAFNGNGFSLLGLSISGVAARYRDESAARGGPLMVTVAPTLPGEGLARSCALYGASVLVLPDASLDAVQMQPSLCLQGEINAAVLAGTLSVIGTHAAVWTTRE
>NZ_CP007220.1|WP_046254983.1|4407995_4408568_-|orotate-phosphoribosyltransferase
MAELDLGPDLNAAERDELAALVRDIAVVHGKVTLSSGKEADYYVDLRRATLHHRAGALIGRLVRELTNDWDYAGVGGLTLGADPVATAVMHAPGRPIDAFVVRKSVKAHGMQRLIEGFEVTGQRVLVVEDTSTTGGSALTAVQAVREAGGEVIGVATVVDRDTGAAEAIRAEGVPYRYVLGLADLGLAGS
>NZ_CP007220.1|WP_046254984.1|4408554_4409346_-|SDR-family-NAD(P)-dependent-oxidoreductase
MAATNSVRPVALVTGPTSGLGGGFARKYASLGYDVVLVARDEQRLSALADELTCRYGVHAEVLSADLADAADRAKVAERIAAGISVLINNAGFATAGEFWTAAPELLHSQLDVNVTAVMELTRAALPSMVAAGAGTVINVASVAGLVSGRGSTYSASKAWVVSFTEGLANGLLGTGVGMHVLCPGFIHTEFHERAGIEMGTIPEFMWLQVDDVVNACLQDIAAGKVLSVPGIQYKAITSVTRVIPRGLVRKFNSVVGRGRGRT

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1521618 : 1536708

Mycobacterium_phage(78.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_052740125.1\|1521618_1523091_+	hypothetical protein	A0A097EWF1	Mycobacterium_phage	2.5e-98	46.0
WP_046253037.1\|1523523_1524018_-	hypothetical protein	A0A0A7RWS0	Mycobacterium_phage	1.3e-22	50.9
WP_052740126.1\|1524282_1524594_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_046255626.1\|1524629_1524830_+	helix-turn-helix domain-containing protein	G8I4H0	Mycobacterium_phage	9.0e-12	58.6
WP_109550621.1\|1524829_1526188_+	DNA cytosine methyltransferase	B5U5L6	Mycobacterium_virus	4.8e-96	47.3
WP_046253038.1\|1526184_1526952_+	hypothetical protein	NA	NA	NA	NA
WP_046253039.1\|1527101_1527425_+	hypothetical protein	NA	NA	NA	NA
WP_046253040.1\|1527417_1527966_+	hypothetical protein	NA	NA	NA	NA
WP_046253041.1\|1527965_1528493_+	hypothetical protein	A0A142F2I2	Mycobacterium_phage	5.0e-33	44.3
WP_046253042.1\|1528492_1528906_+	hypothetical protein	NA	NA	NA	NA
WP_046253043.1\|1528902_1529622_+	hypothetical protein	A0A1X9SH81	Mycobacterium_phage	3.9e-20	36.6
WP_046253044.1\|1529618_1529897_+	hypothetical protein	G8I4H7	Mycobacterium_phage	5.0e-08	49.2
WP_046253045.1\|1529893_1530823_+	hypothetical protein	A0A2H5BLK5	Streptomyces_phage	4.5e-37	34.8
WP_052740369.1\|1531061_1531838_+	hypothetical protein	A0A0M4RAA7	Mycobacterium_phage	2.3e-74	58.3
WP_046255629.1\|1531837_1532182_+	nucleoside triphosphate pyrophosphohydrolase family protein	G8I4I0	Mycobacterium_phage	8.5e-34	69.9
WP_046253046.1\|1532178_1532670_+	hypothetical protein	NA	NA	NA	NA
WP_157889427.1\|1532711_1532855_+	hypothetical protein	NA	NA	NA	NA
WP_046253048.1\|1532921_1533386_+	hypothetical protein	G8I4I2	Mycobacterium_phage	2.8e-48	62.0
WP_046253049.1\|1533560_1533770_+	hypothetical protein	NA	NA	NA	NA
WP_046253050.1\|1533766_1533994_+	hypothetical protein	A0A0K0MX45	Gordonia_phage	1.2e-07	48.1
WP_126315374.1\|1533993_1534707_+	bifunctional DNA primase/polymerase	G8I4I7	Mycobacterium_phage	2.7e-42	43.7
WP_046253051.1\|1534699_1535011_+	hypothetical protein	NA	NA	NA	NA
WP_046253052.1\|1535195_1535444_+	hypothetical protein	NA	NA	NA	NA
WP_046253053.1\|1535446_1535710_+	hypothetical protein	NA	NA	NA	NA
WP_046253054.1\|1535706_1535952_+	hypothetical protein	NA	NA	NA	NA
WP_046255631.1\|1536195_1536708_+	hypothetical protein	G1D5E4	Mycobacterium_phage	1.6e-36	53.8

DBSCAN-SWA_2

1540376 : 1545875

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046253059.1\|1540376_1540844_+	RusA family crossover junction endodeoxyribonuclease	W0LKB6	Mycobacterium_phage	6.1e-35	61.9
WP_157889428.1\|1540846_1540984_+	hypothetical protein	NA	NA	NA	NA
WP_064393432.1\|1540973_1541228_+	hypothetical protein	NA	NA	NA	NA
WP_046253061.1\|1541227_1541593_+	hypothetical protein	NA	NA	NA	NA
WP_046253062.1\|1541585_1542497_+	hypothetical protein	G8I4J9	Mycobacterium_phage	4.0e-54	46.8
WP_046253063.1\|1542493_1542868_+	hypothetical protein	G8I4K3	Mycobacterium_phage	2.2e-19	47.8
WP_081252358.1\|1543132_1544491_+	glycosyltransferase family 2 protein	B5LJK4	Mycobacterium_phage	9.9e-118	48.2
WP_126315376.1\|1544487_1545165_+	hypothetical protein	Q19Y49	Mycobacterium_phage	1.9e-21	37.6
WP_046253065.1\|1545161_1545875_+	hypothetical protein	G1DUV0	Mycobacterium_phage	4.1e-46	47.3

DBSCAN-SWA_3

1559354 : 1584751

Mycobacterium_phage(76.47%)

tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046253078.1\|1559354_1559777_+	hypothetical protein	A0A2D1G9Q5	Mycobacterium_phage	8.3e-07	31.6
WP_046253079.1\|1559843_1560425_+	hypothetical protein	Q855U9	Mycobacterium_virus	2.6e-51	54.2
WP_046253080.1\|1560530_1560989_+	hypothetical protein	NA	NA	NA	NA
WP_052740143.1\|1561021_1561408_+	hypothetical protein	A0A2D1G9P6	Mycobacterium_phage	3.1e-16	44.9
WP_126315378.1\|1561400_1565957_+\|tail	phage tail tape measure protein	A0A142F2F1	Mycobacterium_phage	3.0e-110	32.2
WP_052740146.1\|1565953_1566907_+	hypothetical protein	G8I4D0	Mycobacterium_phage	3.0e-129	65.5
WP_052740370.1\|1566993_1568631_+	hypothetical protein	G1BSP2	Mycobacterium_virus	4.4e-237	70.6
WP_046255642.1\|1568664_1569063_+	DUF2744 domain-containing protein	G8I4D2	Mycobacterium_phage	8.9e-43	66.9
WP_046255644.1\|1571299_1572943_+	hypothetical protein	A0A2L0HL00	Mycobacterium_phage	3.7e-10	36.9
WP_046255645.1\|1573023_1573431_+	hypothetical protein	Q19Y14	Mycobacterium_phage	4.5e-42	67.4
WP_046253081.1\|1573427_1573694_+	hypothetical protein	NA	NA	NA	NA
WP_052740148.1\|1573923_1575309_+	N-acetylmuramoyl-L-alanine amidase	Q9ZX49	Mycobacterium_phage	6.2e-91	45.0
WP_081252225.1\|1575305_1576382_+	PE-PPE domain-containing protein	A0A142F2G4	Mycobacterium_phage	1.7e-32	41.5
WP_046253082.1\|1576403_1576616_+	hypothetical protein	NA	NA	NA	NA
WP_046255649.1\|1576650_1576944_+	DUF2746 domain-containing protein	NA	NA	NA	NA
WP_046253083.1\|1576933_1577254_+	hypothetical protein	NA	NA	NA	NA
WP_126315379.1\|1577284_1577578_+	hypothetical protein	NA	NA	NA	NA
WP_046253085.1\|1577574_1578270_+	hypothetical protein	A0A222ZMT9	Mycobacterium_phage	1.0e-09	33.0
WP_052740151.1\|1578354_1579533_+	DNA polymerase III subunit beta	G8I4E4	Mycobacterium_phage	1.1e-56	35.1
WP_046253086.1\|1579544_1579793_-	hypothetical protein	NA	NA	NA	NA
WP_046253088.1\|1580415_1581426_-	hypothetical protein	A0A2D0ZND4	Rhodococcus_phage	1.9e-44	35.9
WP_046253090.1\|1581736_1582534_+	DUF2786 domain-containing protein	A0A249XTW4	Mycobacterium_phage	9.5e-44	41.3
WP_052740154.1\|1582591_1582960_+	hypothetical protein	A0A1X9SHK0	Mycobacterium_phage	4.6e-09	43.8
WP_046253091.1\|1582956_1583244_+	hypothetical protein	NA	NA	NA	NA
WP_046253092.1\|1583329_1584751_-	ATP-binding protein	C9DGK6	Deftia_phage	4.4e-52	32.4

DBSCAN-SWA_4

2859813 : 2868273

Streptococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046253942.1\|2859813_2860485_-	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	1.9e-16	30.0
WP_046253943.1\|2860586_2861507_+	peptidylprolyl isomerase	A0A1V0SCU1	Indivirus	3.0e-09	33.7
WP_046253944.1\|2861508_2862378_+	class A beta-lactamase	A0A1B0VBP7	Salmonella_phage	2.6e-55	46.6
WP_030093606.1\|2862405_2864772_-	RelA/SpoT family protein	A0A291L9W9	Bordetella_phage	5.2e-13	37.8
WP_162269702.1\|2864801_2865377_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	1.3e-15	37.8
WP_046253946.1\|2865331_2867008_-	hypothetical protein	NA	NA	NA	NA
WP_046253947.1\|2867007_2868273_-	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	3.9e-23	28.6

DBSCAN-SWA_5

4229227 : 4237377

Shahe_endorna-like_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_046256033.1\|4229227_4230352_-	acyltransferase	A9YX16	Burkholderia_phage	2.5e-21	27.9
WP_046254865.1\|4230348_4231617_-	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	1.1e-06	40.3
WP_030096374.1\|4231666_4232467_-	macrocin O-methyltransferase	A0A2R8FDY2	Brazilian_cedratvirus	1.5e-57	53.6
WP_046254866.1\|4232686_4233421_-	SAM-dependent methyltransferase	Q98VI8	Paramecium_bursaria_Chlorella_virus	5.5e-14	32.1
WP_046254867.1\|4233611_4234739_-	acyltransferase	NA	NA	NA	NA
WP_046256034.1\|4234903_4235977_-	NAD-dependent epimerase/dehydratase family protein	A0A0E3IB24	Synechococcus_phage	7.1e-18	25.0
WP_046254868.1\|4236117_4237377_-	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	1.2e-05	40.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage