CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP011271	Gemmata sp. SH-PL17 chromosome, complete genome	27 crisprs	RT,csa3,PD-DExK,csf3gr5,csf2gr7,csf4gr11,csf1gr8,DinG,cas3,cas1,cas2,cas8u2,cas7,cas5u,cas8u1,csm6,csm4gr5,csm3gr7,cas10,DEDDh	6	14	14	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP011271_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_1

400270-400384

Orphan

Consensus_repeat	Method
GGCGAACGGCCGGTGTGAGCCGGCCGGTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_1

>merge|NZ_CP011271|1|400270-400384|CRISPRCasFinder
GGCGAACGGCCGGTGTGAGCCGGCCGGTGGATTTAGTCGTAGACACACCCGCTCGTTGACACGCGCGGTTCGCTCAGAAGTTTCTGGGCGAACGGCCGGTGTGAGCCGGCCGGTG

>NZ_CP011271|1|1|400270-400384|CRISPRCasFinder
GGCGAACGGCCGGTGTGAGCCGGCCGGTG	GATTTAGTCGTAGACACACCCGCTCGTTGACACGCGCGGTTCGCTCAGAAGTTTCTG
GGCGAACGGCCGGTGTGAGCCGGCCGGTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_082838259.1\|409071_410721_+\|DUF1800-domain-containing-protein	unknown	unknown	gnl\|CDD\|378055
NZ_CP011271.1\|WP_052561003.1\|405333_406173_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|333965
NZ_CP011271.1\|WP_082838242.1\|388697_388931_+\|small-basic-protein	unknown	unknown	gnl\|CDD\|275006
NZ_CP011271.1\|WP_082838248.1\|393560_394055_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082838257.1\|407590_407935_+\|carbon-storage-regulator	unknown	unknown	gnl\|CDD\|376847
NZ_CP011271.1\|WP_082838246.1\|392158_392968_-\|ATP-grasp-domain-containing-protein	unknown	unknown	gnl\|CDD\|375726
NZ_CP011271.1\|WP_082838253.1\|402237_403107_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236544
NZ_CP011271.1\|WP_082838245.1\|390700_391774_-\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NZ_CP011271.1\|WP_082838249.1\|394082_395942_-\|Hsp70-family-protein	unknown	unknown	gnl\|CDD\|212667
NZ_CP011271.1\|WP_052560998.1\|400586_401015_-\|response-regulator	unknown	unknown	gnl\|CDD\|381093
NZ_CP011271.1\|WP_162271557.1\|404027_405185_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238121
NZ_CP011271.1\|WP_162271556.1\|401193_402219_+\|histone-deacetylase-family-protein	unknown	unknown	gnl\|CDD\|212525
NZ_CP011271.1\|WP_082838250.1\|396221_398933_+\|spermidine-synthase	unknown	unknown	gnl\|CDD\|223498
NZ_CP011271.1\|WP_162271558.1\|406443_407160_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240291
NZ_CP011271.1\|WP_082838243.1\|389018_390323_+\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	unknown	unknown	gnl\|CDD\|223872
NZ_CP011271.1\|WP_082838247.1\|392964_393564_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052561001.1\|403294_403642_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|259856
NZ_CP011271.1\|WP_157470320.1\|408761_408881_+\|YHS-domain-containing-protein	unknown	unknown	gnl\|CDD\|309878
NZ_CP011271.1\|WP_082838251.1\|399072_400260_-\|class-I-SAM-dependent-rRNA-methyltransferase	unknown	unknown	gnl\|CDD\|224017
NZ_CP011271.1\|WP_082838244.1\|390425_390626_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_052561003.1\|405333_406173_-\|hypothetical-protein	gnl\|CDD\|333965	pfam00263, Secretin, Bacterial type II and III secretion system protein.	1.26036e-09
NZ_CP011271.1\|WP_082838253.1\|402237_403107_+\|hypothetical-protein	gnl\|CDD\|236544	PRK09506, mrcB, bifunctional glycosyl transferase/transpeptidase; Reviewed.	7.53992e-05
NZ_CP011271.1\|WP_082838242.1\|388697_388931_+\|small-basic-protein	gnl\|CDD\|275006	TIGR04137, hypothetical_protein, Chlam_Verruc_Plancto small basic protein. Members of this protein family are commonly found next to markers of rRNA processing such as YbeY. They are extremely lineage-restricted, in the Planctomycetes and Chlamydiae/Verrucomicrobia group. Since classification is based on rRNA molecular phylogeny, this provides additional support for a role in rRNA metabolism. This small protein, about 50 amino acids in length, is rich in basic residues, a third line of support for rRNA interaction.	4.21515e-16
NZ_CP011271.1\|WP_082838246.1\|392158_392968_-\|ATP-grasp-domain-containing-protein	gnl\|CDD\|375726	pfam18299, R2K_2, ATP-grasp domain, R2K clade family 2. Family of ATP-grasp enzymes belonging to the R2K clade, wherein one of the absolutely-conserved lysine residues has migrated to the RAGYNA domain which is a part of the core ATP-grasp module. This family is predicted to catalyze peptide ligation reactions on protein substrates in biological conflict contexts, probably between bacteriophages and their hosts.	3.70262e-11
NZ_CP011271.1\|WP_082838245.1\|390700_391774_-\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	3.0924e-35
NZ_CP011271.1\|WP_082838249.1\|394082_395942_-\|Hsp70-family-protein	gnl\|CDD\|212667	cd10170, HSP70_NBD, Nucleotide-binding domain of the HSP70 family. HSP70 (70-kDa heat shock protein) family chaperones assist in protein folding and assembly and can direct incompetent "client" proteins towards degradation. Typically, HSP70s have a nucleotide-binding domain (NBD) and a substrate-binding domain (SBD). The nucleotide sits in a deep cleft formed between the two lobes of the NBD. The two subdomains of each lobe change conformation between ATP-bound, ADP-bound, and nucleotide-free states. ATP binding opens up the substrate-binding site; substrate-binding increases the rate of ATP hydrolysis. HSP70 chaperone activity is regulated by various co-chaperones: J-domain proteins and nucleotide exchange factors (NEFs). Some HSP70 family members are not chaperones but instead, function as NEFs to remove ADP from their HSP70 chaperone partners during the ATP hydrolysis cycle, some may function as both chaperones and NEFs.	1.68794e-91
NZ_CP011271.1\|WP_052560998.1\|400586_401015_-\|response-regulator	gnl\|CDD\|381093	cd17538, REC_D1_PleD-like, first (D1) phosphoacceptor receiver (REC) domain of response regulator PleD and similar domains. PleD contains a REC domain (D1) with the phosphorylatable aspartate, a REC-like adaptor domain (D2), and the enzymatic diguanylate cyclase (DGC) domain, also called the GGDEF domain according to a conserved sequence motif, as its output domain. The GGDEF-containing PleD response regulators are global regulators of cell metabolism in some important human pathogens. This model describes D1 of PleD and similar domains. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.27887e-46
NZ_CP011271.1\|WP_162271558.1\|406443_407160_+\|hypothetical-protein	gnl\|CDD\|240291	PTZ00146, PTZ00146, fibrillarin; Provisional.	1.99341e-11
NZ_CP011271.1\|WP_162271556.1\|401193_402219_+\|histone-deacetylase-family-protein	gnl\|CDD\|212525	cd10001, HDAC_classII_APAH, Histone deacetylase class IIa. This subfamily includes bacterial acetylpolyamine amidohydrolase (APAH) as well as other Class II histone deacetylase (HDAC) and related proteins. Deacetylases of class II are Zn-dependent enzymes that catalyze hydrolysis of N(6)-acetyl-lysine residues of histones (EC 3.5.1.98) and possibly other proteins to yield deacetylated histones/other proteins. Mycoplana ramosa APAH exhibits broad substrate specificity and catalyzes the deacetylation of polyamines such as putrescine, spermidine, and spermine by cleavage of a non-peptide amide bond.	1.9172e-130
NZ_CP011271.1\|WP_082838250.1\|396221_398933_+\|spermidine-synthase	gnl\|CDD\|223498	COG0421, SpeE, Spermidine synthase [Amino acid transport and metabolism].	8.10487e-13
NZ_CP011271.1\|WP_082838259.1\|409071_410721_+\|DUF1800-domain-containing-protein	gnl\|CDD\|378055	pfam08811, DUF1800, Protein of unknown function (DUF1800). This is a family of large bacterial proteins of unknown function.	3.92463e-121
NZ_CP011271.1\|WP_082838243.1\|389018_390323_+\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	gnl\|CDD\|223872	COG0801, FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase [Coenzyme metabolism].	1.8117e-58
NZ_CP011271.1\|WP_162271557.1\|404027_405185_+\|hypothetical-protein	gnl\|CDD\|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	1.02413e-21
NZ_CP011271.1\|WP_052561001.1\|403294_403642_-\|hypothetical-protein	gnl\|CDD\|259856	cd13834, HU_like, DNA-binding proteins similar to HU domains. This subfamily consists of DNA-binding proteins similar to HU domains. HU is a conserved nucleoid-associated protein (NAP) which binds non-specifically to duplex DNA with a particular preference for targeting nicked and bent DNA. It is highly basic and contributes to chromosomal compaction and maintenance of negative supercoiling, thus often referred to as histone-like protein. HU can induce DNA bends, condense DNA in a fiber and also interact with single stranded DNA. It contains two homologous subunits, alpha and beta, typically forming homodimers (alpha-alpha and beta-beta), except in E. coli and other enterobacteria, which form heterodimers (alpha-beta).	9.70249e-19
NZ_CP011271.1\|WP_157470320.1\|408761_408881_+\|YHS-domain-containing-protein	gnl\|CDD\|309878	pfam04945, YHS, YHS domain. This short presumed domain is about 50 amino acid residues long. It often contains two cysteines that may be functionally important. This domain is found in copper transporting ATPases, some phenol hydroxylases and in a set of uncharacterized membrane proteins. This domain is named after three of the most conserved amino acids it contains. The domain may be metal binding, possibly copper ions. This domain is duplicated in some copper transporting ATPases.	9.43473e-05
NZ_CP011271.1\|WP_082838251.1\|399072_400260_-\|class-I-SAM-dependent-rRNA-methyltransferase	gnl\|CDD\|224017	COG1092, COG1092, Predicted SAM-dependent methyltransferases [General function prediction only].	7.29777e-129
NZ_CP011271.1\|WP_082838257.1\|407590_407935_+\|carbon-storage-regulator	gnl\|CDD\|376847	pfam02599, CsrA, Global regulator protein family. This is a family of global regulator proteins. This protein is a RNA-binding protein and a global regulator of carbohydrate metabolism genes facilitating mRNA decay. In E. coli CsrA binds the CsrB RNA molecule to form the Csr regulatory system which has a strong negative regulatory effect on glycogen biosynthesis, glyconeogenesis and glycogen catabolism and a positive regulatory effect on glycolysis. In other bacteria such as Erwinia caratovara RmsA has been shown to regulate the production of virulence determinants, such extracellular enzymes. RmsA binds to RmsB regulatory RNA.	2.38505e-20

>NZ_CP011271.1|WP_082838251.1|399072_400260_-|class-I-SAM-dependent-rRNA-methyltransferase
MSAKVILKAKRAQPFFGRHPWVFAGAIERVEGEPADGDEVELVSHGGNFVARGLYNSQSKIHVRLYCWEPDVLLDRAFFHSRISRAVQLRHDVLKLNTPGGGYRVCFSESDYLSGMVVDRYGDWLTVQFTALGLARRREIIIDVLRELLNPKGIYLRTEKGIGKLEGVELHDQLLWGEPPPADLSIAENGMRFLVNLTEGQKTGYYLDQRDNRAAVARLCVGKRVLDAFCYSGGFGLYAASAGASEVLSVDASEPALELARRNANANNLSNITFANADVFKHLGELVAAGRQFDVVVLDPPKFARNRAAVPEALKGYRRLHQLALKLLAKDGILVSCCCTGLIAMTDLEELLAQVSTEARRDLQIIERRGPAADHPVAVTCRESGYLKCLVSRVL
>NZ_CP011271.1|WP_082838250.1|396221_398933_+|spermidine-synthase
MSSAPAPVSAPIPLPVGRLVGVGAIIFFANAALLVLQLVAGRLLSPYIGSSLETWTSIIGVFLAGIALGNAFGGRLADRYPSPKTLAILLGVGVVAALWMLLFPQLLASNGAYKSIPLGPRIPVLAAILCLPAGFVLSLLTPLAIKLGLPDVAHTGRVAGLIFALSTLGCLVGNYVTGFYLIPTFTVNALVLFSAGALVVLAMVALVVVKPSPSAPDAATNGGRTEATDASAGLNPHAFSDIRRAYLIVFLASFCGMTLELTASRVLAQYLGVSLFTWTGIIGVMLAGTALGNFTGGQFADRPKNTLAWLAGAVTFLGTIAVAGVVALVAAYDQDQPVVEHVLGIPAQNWAKYAPLSYEAFEERGDEIRVFIRGEVPELLPKLRIQLLAGVGIGVILGALLGYFVFGSLKRGSAPDPRSVLAATLCAGGAATVFLFVTMALISRYHLFELWDPVVQVLVWTFSMFFLPMFALGMVSPQVIRLAVPDVSQAGAVAGRVYAWSTVGAIVGTFAAGYVLLSAAGMNRTLLAASFVVTVTSLIVAKVWNNNSLLYLFSIVLGGIVGGFILTARTNRDTGIMVESNYYTIKVTRESPFNTRLKLTLDHLVHSSVDPYDPGYLYYHHEHTQMEFLRLARTQTAEPKALVIGGGGYTFPRYALEMMPEAHVDVVEIDPKVTQVARDHLGLRDYPGLQAIHMDGRQFVSEKAAPGSYDLVIQDAVNDLSVPAHLMTKEYNDAVKVSLKPGGAYLLTIIDSIAYGKLWKAAMATLTKTFPAENIVLLTAERPAPAGTAAGDSWDQTRRVLVIYASDKPLDLDKLHGAVVDQLSPGFAAGLAVGTAGGADIRAALPITLSATPLARDGVRIYTAEVPAARLKPYTDREPGVILTDQFCPIDNLMAEVFRQRYK
>NZ_CP011271.1|WP_082838249.1|394082_395942_-|Hsp70-family-protein
MSSRFVVGIDLGTTNSALAYVDTGAGKDAKVTPFPIPQVVAQGSVEDRPLLPSFLYLPGDGEQPAGAMKLPWDAKRDYCVGEFARAFGSQVPTRLVASAKSWLCHPGVDRKAQILPHRAPDTGARKVSPVDATTRYLKHIAEAWNHVIAKEVAANRLEAQDIVLTVPASFDAGARELTVEAARAAGFEHLTLLEEPQAAFYAWLDRTGDEWRKQVSVGELVLVADVGGGTTDFTLIEVGEEDGNLALTRLAVGDHLLLGGDNMDLTLAHHAAQTLAAKGTKLDAGQMVQLTYACRNAKEELFARPKLQSAPVTVLGKGRSIVGGTIKHELTRADVEKVLVDGFFPDCPRDATPGLGRSSGLQELGLPYVADAGITRHLASFLARQAEALANRESTTAASKKKKATSDAASIPGAILFNGGVFKGDVLRTRMLNVLGSWAKSAKADPTRDLPGADLDLAVARGAAYYGLVKRGKGVRIRGGTARAYYIGVETNMPAVPGFAPPIKAICVAPFGMEEGTEADIPSYEVGVRVGTEAEFRFLGSTVRRDDGAGVVVEEWEGQIDELSPVKTTLEAKGAAAGGQVVPVHLHSKVTAVGQLELWLQSRDGKNRWKLEFNAREGK
>NZ_CP011271.1|WP_082838248.1|393560_394055_-|hypothetical-protein
MGKLRDLLQTEADRYRNEKTKRQQALNEWLELLNSLFAQIDSWLKASDPDNLLEILSDELVANDPALGEYKAPMRRITLGKTSVEIVPRARYVIATIQPPNEQPVRAHGLVEIRSRGFATHNLYQLPGGLWYIFDRSSPLSTGINAVEPLNADRFEAALASLLR
>NZ_CP011271.1|WP_082838247.1|392964_393564_-|hypothetical-protein
MKTLDEAWAWYRAVAERAKRLTHLAKFWDGFPWDQEHDWVEQVARDSVLRQVAANQMEKDAQLVTNELDDLAVLLLFSVFEANVRDLVEMQVRPEVDKLLHPALRSAGEDVLQAITEGSFFRVLEPFKSQVSHYLIETVNQVRRYRNWVAHGRRPLKEDEQLASVQPIEAYQRLKRFLEHLAPPPNVAEEAQAQEHPPT
>NZ_CP011271.1|WP_082838246.1|392158_392968_-|ATP-grasp-domain-containing-protein
MTLPVWLIESGVYGSEIEPFAAEVRRQGMECRFVTYREIVKGPPPLPPGSCAITYGTYPTVRHAILRLGWTPGGWCSPENLDCTAYYPHFADFLLNQRHEIITGAGAIREKERLFHTFGRNGYVFARPTSVHKLFVGRLIAEDDFETAPAPTRYDPETKIVVAGPRELGAEWRLVVAHNEVIAANRYAEGGTRSVAAGCPNEVLTFANAMFETVGWRPDDVFMLDVCESTDGLRLVELNSFSCSWIYACDLVSIIRATSQCAINGRLYK
>NZ_CP011271.1|WP_082838245.1|390700_391774_-|DUF1559-domain-containing-protein
MMPGTRPNRSRSAFTLIELLVVIAIIAILIGLLLPAVQKVREAAARMKCQNNMKQIGLAVHNFESANGVIPYSKNRWTLVGPLVQLLPYVEQENIYKQLDPRIYNLVPSSVTTSPIDGGDWLVAFWPSTFSVSRNRVKMFECPSDPSLYEASGAIATNIGQGNISSSGGATQSGAGSGGGYTSSSLINAGGLPGLTNYMPNAGTLGQYNVTNTASLSQPFYAAHAGPFTYENRTTIIGITDGSSNTIAFFEYTGDFANSGASSGPLGARTWSTAWMSATGMPLYWSATSRPGFYSASSFHTGIINAVFCDGSVRSLRSGNALPTSAAEIANRTNTSWDALQRYAGSRDGDTPTDAIN
>NZ_CP011271.1|WP_082838244.1|390425_390626_-|hypothetical-protein
MKRFTFPVLLAAFVVLAAGCGKDDDPNKNLKPIDPNTPKPMGAGAGPAPKQGPGDGSKAPAPVSPP
>NZ_CP011271.1|WP_082838243.1|389018_390323_+|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase
MPLAYIALGSNLGDRWGTLSAAVQRLRAEPGLRVVTRSGFYETAPVDCPPGAGEFLNAVVGVETDRSPHDLLQFLHQVEHQFGRIRTETNAPRTLDLDLVLYDDAVINTPELLVPHPRAHDRAFVLVPLAEIAPDVVHPVLKKTIRELAAALARDDVRVLSAPGRPPARELSGLRALVTGSTSGIGRAIATAFAEHGADVVLHGRGFIPPLGAASEDEMTAFGIGTEAILRSYRDRGVRAVGIGEDLSVSGAAKRLAARAWDAFDGLDILVCNAGADTLTGAAAKWSFDEKLDALLAIDLKATMHLSRDIGTRMKERGRGCIITIGWDQAETGMEGDSGQLFAAVKGAVTCFTRSLALSLAPEVRVNCIAPGWIRTAWGETASPVWQSRVRDETPLEVWGLPEDIATTARWLASPAAAFVTGQTIRVNGGAVRA
>NZ_CP011271.1|WP_082838242.1|388697_388931_+|small-basic-protein
MSIDKSLKRKAGMSRQRCVLTRAERIAKMLENGKFGTDSSPYGLPKTRVQKVALKKKVKKEAAEGDAAPAAGKGGKK
>NZ_CP011271.1|WP_052560998.1|400586_401015_-|response-regulator
MPRILIADDNPSNADLFDAHLDGTGFETKLVYNGVDALAAASEWKPDLILLDVMMPKMSGFEVCRRLRADPATRDVSVLMVTALDQANDVETAVDAGTDDFITKPISGRELVLRVNAMLASRNEPTPTDRALAYIGRVQQGL
>NZ_CP011271.1|WP_162271556.1|401193_402219_+|histone-deacetylase-family-protein
MRVILNPKHADHVPPGEMEGGAVIPSYEAPGRFEVIRAALESAGGFRFEEPPKPSEECVAAIHHAAYITYLREASAEAKRARDPAAKQLWPTVFPFGPNPRATGTRALRGQFCFDTYTPILPGTFASALGGANAAARAADLIAEGAERSVYVLTRPPGYHAEHDRCGGYCYFNNAAVAAERLANRGSVAVLDLDVHHGNGTQHIFYSRADVLTVSVHGDPAGLYPFFSGFADETGTGAGLGANANFPLPPGTGVKEYRPALAAAVEAVRRFKPAFLVFAFGADAHESDPIGGFKLSTKFFAEMGTAVREIGLPTVIVQEGGYNLTTLGACVTEGLKAIDAN
>NZ_CP011271.1|WP_082838253.1|402237_403107_+|hypothetical-protein
MAFQFNCPTCGTAMIGSADRVGRDVRCPNCQAVFPSPEPPLLETVEPLPIDDRYPEPDPPREPRRREPRDDYDREYDREYDEEPRPRRRRRPPPPPPGRGPLFWIVIIFGVLFLGTCACCGGGFLLIPGEKWHKHQSAEGSFAVDVPMPVKKDMPIPGVKLEPGQRAEGGILWKRGEVYLISYMPIPPVGQRAMTEQALLDEAVNDMRKDRAIKRIVRDERVTVSGYPGREVEYLYEDGGTYVGRIVISNRYLYLVVAGGRFVSPGNANVRKFLDSFEVTGAKVQFGRP
>NZ_CP011271.1|WP_052561001.1|403294_403642_-|hypothetical-protein
MAKAAKAAPKKAAKKAMTKSQLVGHLAEKTELTKKQIEAVLGAIVDTVTEQLSSSGPKKFVFPGLARMSLTQVKSRPGGEVKKNPLNGKEYTTKARPAFNKVNIRPIKAIKSALA
>NZ_CP011271.1|WP_162271557.1|404027_405185_+|hypothetical-protein
MNLVSRVSLLALGPLAAAACRAAGAAAVSDGVSAVARVLTERLTDQSRRVTDALGAASTRAWHALELVLAGDSALAFADRADDRAFREQARLFLLNAQFDGRAASDSDFAVRCLDELRTARMSGVLGGDADPNALAARLGDLAHFSDPAAVVRGQWVLADEIGAELRARGFSTLAAFLVLRPAGDPNADPLLAVAVRYYFRRAVEDDPRLFQGLAFSQLERIGRAQEDAASALAGVMSRLDALHATLRDQELPLAEEFVEVPVPSVADRFRDETNGVLAVSPDESRVLGGSRYDGKLRLFDARTGKELRRLPGHAGWVTCVAFAPDGSRALSGGEDGAVKLWDVTSGKLLRTWPQKGTRPNALAFTTDGRAQIRGADGAVLVWKV
>NZ_CP011271.1|WP_052561003.1|405333_406173_-|hypothetical-protein
MNLRLLCALFVAGTHLAPIAAAEPASTRTATAPLVTFEVRVVRVSAEPGAVLKAVKPEEGGVAFLSDEQLKALFADAQSDPRANILCTPKVVASSGEPATVRVGSNREFVTGLEARQVKGSVALVAKKTVVELGDVLTVCGSVSADRRSVSVSTGYTNTSLASDLIPLVPVTTQTPAMNGGPAIPFTQFLQAPQVRTIAIEKKELSLPSNGHVVITGPVTTVEERTEYGPPVLSNIPYLGRLFKSVAYFKREVRTLLVVSARVVEEELPVAPAPRSVGR
>NZ_CP011271.1|WP_162271558.1|406443_407160_+|hypothetical-protein
MAVFTAKVPVAIATGIVGFLLGGGLVGVVMTYSLSKPDQQAAAAPGGDEEKGGDPKGGKGGMPGGGGGGKGGKGGGGGGGGKGGGAKGGGGGGGGPGGGGFGGGGGGGAPGGQRGPSAKFQLTQLVNKLDALTKKPLVVELTADQKKQTKELLAGLEAADDLKEEDAKSKLDALLKLFEANKETLEAAGYRWPGGGGGGMGGGGMGGGGMGAGAPPPNPFKAGEGADRLKSLQSTLGK
>NZ_CP011271.1|WP_082838257.1|407590_407935_+|carbon-storage-regulator
MLVLTRRPGESIIIAGDIKITVVNVGPGRVKLGIEAPPHVRVDRQEIHDKIEQSADVLAAVGGEVGIDSQNTMISSGPDTTTISTAPVGAPQVAPATVPPLGKLSKYRLPRKPR
>NZ_CP011271.1|WP_157470320.1|408761_408881_+|YHS-domain-containing-protein
MKVSYKGKDYWVCCSGCRDEFKENPEKYIKEAEAKAKKQ
>NZ_CP011271.1|WP_082838259.1|409071_410721_+|DUF1800-domain-containing-protein
MAEALPSDLAKVDPREAWAPWKPANGEWNRKWVAHLFRRAGFGATPAETDKALAEGLSKTLSHFMTGDADAADRLELLTETGKYYTEPVSLRVWWLYAMTEGGYPLREKLALFWHNHFATSYAKVRSTKLMYEQNVTIRKHALGAFRPFLLDMSRDTAMLVWLDSNRNVKGAPNENYAREVMELFSLGVGNYTEKDIQEAARALTGWHHDAEVLKFEFNHELHDEGSKTVFGKTGKWTGEDVVRLCCDQQACATFLVSKLYSFLVSETPPPKALLAPLADQFRKSDYDIAALVKTILGSRLFFSEHAYHKCVKWPVECALGAVRSAVGERIPLSDVVDPLAKMGQALFAPPNVKGWRTGTDWLNSATLLARNNFAEKVAVGEWSRNGRPRPSQQFGFVAEPTKVDAPPSEPAPPPAPEAKHDICTAIFAANPKDIAAVVKQMSTLLYGEAAAPAQVKKLETFLLTPGPTAGAAPAAPKGPKPKSKGLTPPETKSADGPKAKTESEPKPKKAEPPKPLDPKDVKLDSPEFKARVREAYHAMMCLPEYQLN

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Crispr_ID: NZ_CP011271_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_2

1048641-1048726

Orphan

Consensus_repeat	Method
CGCGTTGGTATCGTTGATTGCGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_2

>merge|NZ_CP011271|2|1048641-1048726|CRISPRCasFinder
CGCGTTGGTATCGTTGATTGCGTAGCCCGGTTTCGCGTGGGGTATTGGCCCGTCGGGGAGGGGCGCGTTGGTACCGTTGATTGCGT

>NZ_CP011271|2|2|1048641-1048726|CRISPRCasFinder
CGCGTTGGTATCGTTGATTGCGT	AGCCCGGTTTCGCGTGGGGTATTGGCCCGTCGGGGAGGGG
CGCGTTGGTACCGTTGATTGCGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_082838630.1\|1050900_1055220_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379219
NZ_CP011271.1\|WP_052553163.1\|1037412_1037868_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082838627.1\|1044716_1048595_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224117
NZ_CP011271.1\|WP_052553165.1\|1036478_1037393_+\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NZ_CP011271.1\|WP_082838622.1\|1032725_1035026_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224423
NZ_CP011271.1\|WP_052553152.1\|1048820_1049273_-\|IS200/IS605-family-transposase	unknown	unknown	gnl\|CDD\|376616
NZ_CP011271.1\|WP_082838621.1\|1031568_1032678_+\|DUF1501-domain-containing-protein	unknown	unknown	gnl\|CDD\|369346
NZ_CP011271.1\|WP_082838624.1\|1039048_1039708_+\|RraA-family-protein	unknown	unknown	gnl\|CDD\|319245
NZ_CP011271.1\|WP_162271585.1\|1057862_1059578_-\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NZ_CP011271.1\|WP_082838629.1\|1050265_1050688_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082838626.1\|1042428_1044345_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_157470347.1\|1059696_1060251_-\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NZ_CP011271.1\|WP_082838634.1\|1063015_1063849_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237660
NZ_CP011271.1\|WP_082838628.1\|1049648_1050275_+\|RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|224511
NZ_CP011271.1\|WP_082838631.1\|1056200_1057613_-\|DUF1501-domain-containing-protein	unknown	unknown	gnl\|CDD\|369346
NZ_CP011271.1\|WP_052553143.1\|1055318_1056104_+\|TIGR03000-domain-containing-protein	unknown	unknown	gnl\|CDD\|274383
NZ_CP011271.1\|WP_162271584.1\|1040734_1042432_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052553135.1\|1061608_1062583_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236776
NZ_CP011271.1\|WP_052553161.1\|1037991_1038948_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|277341
NZ_CP011271.1\|WP_082838625.1\|1039825_1040689_-\|carbon-nitrogen-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|143587

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_082838630.1\|1050900_1055220_+\|hypothetical-protein	gnl\|CDD\|379219	pfam13490, zf-HC2, Putative zinc-finger. This is a putative zinc-finger found in some anti-sigma factor proteins.	1.66822e-07
NZ_CP011271.1\|WP_082838627.1\|1044716_1048595_+\|hypothetical-protein	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	5.58089e-19
NZ_CP011271.1\|WP_052553165.1\|1036478_1037393_+\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	7.4495e-32
NZ_CP011271.1\|WP_082838622.1\|1032725_1035026_+\|hypothetical-protein	gnl\|CDD\|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	4.04858e-07
NZ_CP011271.1\|WP_052553152.1\|1048820_1049273_-\|IS200/IS605-family-transposase	gnl\|CDD\|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	1.97468e-32
NZ_CP011271.1\|WP_082838621.1\|1031568_1032678_+\|DUF1501-domain-containing-protein	gnl\|CDD\|369346	pfam07394, DUF1501, Protein of unknown function (DUF1501). This family contains a number of hypothetical bacterial proteins of unknown function approximately 400 residues long.	1.20956e-40
NZ_CP011271.1\|WP_082838624.1\|1039048_1039708_+\|RraA-family-protein	gnl\|CDD\|319245	cd16841, RraA_family, ribonuclease activity regulator RraA family. RraA protein family is named after the regulator of ribonuclease activity A (RraA), a protein that binds to RNase E and inhibits RNase E endonucleolytic cleavages. Members also include proteins with other functions, like a 4-hydroxy-4-methyl-2-oxoglutarate/4-carboxy-4-hydroxy-2-oxoadipate (HMG/CHA) aldolase from Pseudomonas putida, which catalyzes the last step of the bacterial protocatechuate 4,5-cleavage pathway and the uncharacterized YER010Cp protein from yeast, an organism lacking RNAse E.	4.77419e-45
NZ_CP011271.1\|WP_162271585.1\|1057862_1059578_-\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	1.74713e-37
NZ_CP011271.1\|WP_082838631.1\|1056200_1057613_-\|DUF1501-domain-containing-protein	gnl\|CDD\|369346	pfam07394, DUF1501, Protein of unknown function (DUF1501). This family contains a number of hypothetical bacterial proteins of unknown function approximately 400 residues long.	1.25152e-170
NZ_CP011271.1\|WP_157470347.1\|1059696_1060251_-\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	1.61733e-20
NZ_CP011271.1\|WP_082838634.1\|1063015_1063849_+\|hypothetical-protein	gnl\|CDD\|237660	PRK14289, PRK14289, molecular chaperone DnaJ.	0.00777319
NZ_CP011271.1\|WP_082838628.1\|1049648_1050275_+\|RNA-polymerase-sigma-factor	gnl\|CDD\|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	4.02773e-34
NZ_CP011271.1\|WP_052553143.1\|1055318_1056104_+\|TIGR03000-domain-containing-protein	gnl\|CDD\|274383	TIGR03000, plancto_dom_1, Planctomycetes uncharacterized domain TIGR03000. Domains described by this model are found, so far, only in the Planctomycetes (Pirellula sp. strain 1 and Gemmata obscuriglobus), in up to six proteins per genome, and may be duplicated within a protein. The function is unknown.	9.74665e-13
NZ_CP011271.1\|WP_082838625.1\|1039825_1040689_-\|carbon-nitrogen-hydrolase-family-protein	gnl\|CDD\|143587	cd07197, nitrilase, Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes. This superfamily (also known as the C-N hydrolase superfamily) contains hydrolases that break carbon-nitrogen bonds; it includes nitrilases, cyanide dihydratases, aliphatic amidases, N-terminal amidases, beta-ureidopropionases, biotinidases, pantotheinase, N-carbamyl-D-amino acid amidohydrolases, the glutaminase domain of glutamine-dependent NAD+ synthetase, apolipoprotein N-acyltransferases, and N-carbamoylputrescine amidohydrolases, among others. These enzymes depend on a Glu-Lys-Cys catalytic triad, and work through a thiol acylenzyme intermediate. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer. These oligomers include dimers, tetramers, hexamers, octamers, tetradecamers, octadecamers, as well as variable length helical arrangements and homo-oligomeric spirals. These proteins have roles in vitamin and co-enzyme metabolism, in detoxifying small molecules, in the synthesis of signaling molecules, and in the post-translational modification of proteins. They are used industrially, as biocatalysts in the fine chemical and pharmaceutical industry, in cyanide remediation, and in the treatment of toxic effluent. This superfamily has been classified previously in the literature, based on global and structure-based sequence analysis, into thirteen different enzyme classes (referred to as 1-13). This hierarchy includes those thirteen classes and a few additional subfamilies. A putative distant relative, the plasmid-borne TraB family, has not been included in the hierarchy.	9.79431e-85
NZ_CP011271.1\|WP_052553135.1\|1061608_1062583_-\|hypothetical-protein	gnl\|CDD\|236776	PRK10856, PRK10856, cytoskeleton protein RodZ.	0.000332853
NZ_CP011271.1\|WP_052553161.1\|1037991_1038948_+\|hypothetical-protein	gnl\|CDD\|277341	cd07396, MPP_Nbla03831, Homo sapiens Nbla03831 and related proteins, metallophosphatase domain. Nbla03831 (also known as LOC56985) is an uncharacterized Homo sapiens protein with a domain that belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	1.51587e-14

>NZ_CP011271.1|WP_082838627.1|1044716_1048595_+|hypothetical-protein
MMAPLPNPAPGDRPDLPKVRLDARTGIGRAVSYDFTGEEFLIGAAAGCDLRLTVPGAPLVVVQLTRKPDFVGIRRVTAAMPVLLNGSPIQAGAVYPLQHTDTVHVAGVVVVVQIPAQAVPEPPVTYIAPKFASLDEVPLASPVDDEPELPAPDFTAEYERLETRKRALDAEEADRRASWEARDAELIRRRRDLDQFAEELEADRALWHDRRRAIEQELADRRAEEAAAREAELARTRDELVALKQQWTDECGKQREELARRGEQLRTDREAFEGERTAFEPQLQSLRAEQARTAVQMQELSRQRELFAADRDIFERASDTFEARRAAETDRLTSWETDLNVREQVVTHREGLVRTARDEYESERARFQEDLVRLERRMAAAEELERNLTLRTQEVDARLDQLRYDAAEWEETVRLAASEQERLRAEAERLDRQKAELDTQTATLAERAGQLEAQQAVVAVFRAKLDRSRQDMEREAWQLAAARAREDESMAELRRRIQEAEEVRAALNAVQENADQERQRLDERDSLLTAGLEEIRVQKEALAAEATRIQERETELDVRSAEFAEQAGMLKGRMTQAVDLQSRLEADRVAVREREAAMSQSEEARQALQEQLRRRAEDLNTRGKALDDLARQMAAERASVNEARAALEASRQAAEDELASRRLELAAQAASVERQAVDFADKEQALARQVGRLKDVGAAVAAERKSLAAARATWEADRAAALEADQAARDQLARFRTEVEADLEALRTQAPELDEQAKLALDRLAGARDMLRGHLNELNEFARTSRTDLEAARAQIREESERLREKNEELDRAKDEHRLAVTAFRQQLIEWQGTVAEMRRLLSSSETRLDAKQAAAAEAATAAADATQKLAEETDRLRREREEFTARRTEMERHLSDMREWYRKKLRELARGNAERGARGTESEPEPALPRLADTGDSTPLPTGVVPRGAETVLEELEPGDRQLGELLRSSGLVDPDTLTALWEEATRQRRTLRQVLLASGAITLYQLALIEAGNLDSLVLGRFRVIDRLRVAPKEAIYRVHDPKRTGEKSGGLYLLRHLSEAEMQDAVHPDEFRQRFSAARDAASPHLAGIVEVLDINGRPAVLQEWLTGLFSADWPAFAAHPGCWVRLATMAAGALDAAHRVGLAHGRLTSDSFVLTSDGVLKVTGFGEPSWLIGPAGPETSDATFAADLRAFGQVAFGWSQLAGRKRVAKTKGFPESLWAVIRRLEADAEPPMADTVAAAQPYQSAAELLADLQRIARDTPFSDDAWEKLLKHVADNAPDAPAGLKKAG
>NZ_CP011271.1|WP_082838626.1|1042428_1044345_-|hypothetical-protein
MKLSVPPPPPPPPSDGTPGAGSPEEPNEQPDATASAPVEQPAAPGAPKSKPAVWPSWFSGIDAALVGLVVLFAFVAASFAARNSDLWLHLATGKRLFAGEYVPGGSDPFSYSAEGRAWVNHSWLAAPVMYLLYGGDGVVLVAAKALLVALAFGLLIAIRRPQFALWPWAAVACVGVLAAAPQFTLRPLVASMLFFAATLFLLFRVPHKKGSKQFPIATGVTFWLWASCDQWFFVGPLALALLLLGDLIQKYGFNAPDEPEGTTDADALGRLPGTAALAKALGIGLLACTLTPNHVRVWQLPFELVGAPGAASDPSMKLLLSAPYDMGLYAENPQLGYNANGLCYVLLLVLGATVVALAGSLGVGRVRVSHVALWFGFAVLSLLSVYAVPFFVLVAVPLVAAQLNAFGARAELKTWGDPRTRLLLIASSGGRVLSVLGVCILCVLAYPGWVHPDASTPALARRVAWAVEPDRGLVQAAEQLNTWRQGGDLPAEARGIITNIDLANYAAWFAPTERVLINGRLNHHRRELADYIALRRGFGLVPTENELPQQRDATDVLARHSAEYVVMSASVNPGSSAPDPRFAAQVPILVLYQQWGTWSEWYTDGRTAVFGWRPEPTGAGPRSRPCTWTPRSRRSDRG
>NZ_CP011271.1|WP_162271584.1|1040734_1042432_-|hypothetical-protein
MKKVPDPVVQQLLVQAGWEEAFVRAPRPAPAGAVEAFGWLDYKNALLQRQVIRQNWVHPATVGWLAGQHTWHHFALRTAGALELIQIVPQYAGAETEAAAMRALPVLALRAARRAIAEDPDHPDGYYALAHALRDTDLPFSESERSLGMVVAYRQCLSRYPKADRYARGQFSARASQVAFELAQTYLGRRLPWSERGRNAIEFTGFPVDVAPFRDRLGIGQPVFQNVETKAYQRAAFNAPNAPLAPLYNGLPFLLPLDTAREALQTALEYAPIDFPNESDEQKKFAKQIETYKTAVDNLLIRYKERYETTKGLSPKLPALVISAIRNCMPSEALNLLNNKELDPESNKDGYFTALQIALELATGQIENASERLKRLSEPDNAKKLEQLPALESIQALKYQTLIIAGEYKAAGDTLEALSPNIGQLDKLKKPPGPELPLEYVQRVIVAAGLTKNPEKFPPRLLAPPLSMIPGHDQVLHAHIWLNTWDSLRVMIQRGILEHLTSESHFFTRRGVLFLLEGDVPSAKERFKESLRKPPEGWGLPSTHSPLADQYLLLIERAEKKAVKP
>NZ_CP011271.1|WP_082838625.1|1039825_1040689_-|carbon-nitrogen-hydrolase-family-protein
MSNWTVAGVQMSCALGDRAANRAALVTNLRRAAERGAQLVVFPECVLSGYGFTSRAHALSAAEPLPGPSTEFVAKACAELGVWAVFGLLESAPGDKLYNAAALVGPRGFVAGYRKLHLPCLGADRFTDPGDRPLAVHDLGGLKIGMNICFDGSFPESARILTLLGADLVVLPTNWATNARKMAELVSAARAWENHIYYLAVNRVGDESGFRYIGLSSAADYTGNVLHFAPEGEEAIFTIDVDPAAAAQKRVVTCAGEYEIDRVNWRRPEMYGPLVANPGAFTGHFNK
>NZ_CP011271.1|WP_082838624.1|1039048_1039708_+|RraA-family-protein
MTTPPRALEWVDRLAKLYTPVVADVLDKLGYRNQCMNPRVRPLWPEAKAAGFALTVQTVPARDVAPPHPYAGELAAVDSLQNGDVLVVSESACSFWGELLSTAATYRGCRGVVLDGPTRDSLAIKEMGFPVFHVGFHPADSLGRLDVVTHNVPISCADVLVYPGDLILADHDGIVVIPSVAAEEALRLAEEKVSGENLVRKALAGGMTTTEAFKKFGIL
>NZ_CP011271.1|WP_052553161.1|1037991_1038948_+|hypothetical-protein
MTSPSRRDLFGAAIGAAALPGFISTARAADRKPVLRAAHITDVHITKDREAPQGVAAMFSHMASQKDGKPELILNTGDAVMSVDGKTTGAKAAEHIAVWKEAVKSAPAPIYSCLGNHDVWDGNEPTDAIPAEKKGFALMTGVLGMPAPYYSFDKNGWHFVSLNSMCNWPKYATLSPEHFDWLKADLAKTKLPTVVLSHVPILSVTSQVYGDGCRKNNDNVVPGVWHHADCWAISEVFRKNPHVKLCLSGHMHTCDRCEYRGVWYICGGAACGAWWGGSEYGFPPCYGKLDLFADGTFSYDFVDYGWKARKWQGKELKD
>NZ_CP011271.1|WP_052553163.1|1037412_1037868_+|hypothetical-protein
MRAIFFAAATTVAVVLAGCGGDVPRGRVHGTIKYQGKPLTGATVIFIAQDSKTHVLDLKPDGTYDVSGVALGPIKVSIQTVAPRSAVKGEFDPPSSQAKGVTDEKAGKKSSSAEVSKVAGPMLPARFADADKSGLSFDLKEPDQEWSVDLK
>NZ_CP011271.1|WP_052553165.1|1036478_1037393_+|DUF1559-domain-containing-protein
MAHARQKSKAGVPSGFTLIELLVVIAIIAILIGLLLPAVQKVREAAARMTSQNNLKQMALATHNYHDANNQFPLAWNDWDGSDSAAMWNKAGSALFYILPYIEQDNLANLANKGSTNYFWSVYTNYGVKSYVSPSDPSCPPNGLYNDAGWGNYGVTSYAANFQALGWWFKTSNNKVMRMTSLTDGTSNTIFYAEKTAVCLNNAIPSGYSGAKYNIWAYGRTSWNEWNPVFGYQITGSASKFQVNPTWAATNSNCDPRLASSPRSAGILVALGDGSGRMVSAGVDPNTWWWACTPTGGEVLSSNW
>NZ_CP011271.1|WP_082838622.1|1032725_1035026_+|hypothetical-protein
MKPAFHRVLFLIVSSSALSAAPLFAADPVALPNTKPLGDEGNLSEKMVAGMHKYLDRALAASVKSREALWKTDNSSPEAFAKSVDPNRERLRKYLGVVDKRSIPHLEYLGVPERFAVAETERYKVFAVRWAVLPGLDAEGLLLEPRGKIVAAVVAVPDADQTPEQIVGLSPGLPAISQFARRLAESECRVLVPVLIDRRDTLSANPKLGRTTNLPHREFVHRMAYEMGRTLIGYEVQKVLAAVDWLSAPKDRPPVWAAGYGEGGLVALCAGALDARIERLAVSGYFGAKPDVWNAPLDRNVWGLQHEFGDAELAALAAPRLVFIGNCETPKFDGPAKPQPGRGGAAPGTLGGCPIEQIETEWKRINDLTGGAGVNKCSMALAEKLVPAAGLDQLVLPLNLRNKATDGRVPPTDLRQDFSPVARHKRQFDQLVAYTQKLWRDSEAVRKEFWKKADARSPEAWEKSCDWYRDYFHTEVIGKLPDPKGPLNPRTRQVYDEKTWAGYEVVLDVYDDVFAYGILLLPKDLKPGEKRPVVVCQHGLEGTPRHTIDVEQRTVYNHFSRRLVELGYIVYAPQNPYYGENVFRQVQRKANPLKLSLFSFIIRQHQRTLDWLETLPNVDPKKIAFYGLSYGGKTAMRVPAVEKRYCLSICSGDFNEWIGKNVSVDLDRSYMWTREYEMYEFDLGNTFNYAEMAYLIAPRPFMVERGHDDGVGTDEMVAYEFAKVRYLYANRLKIPGNTTIEFFPGGHQINAKGTFAFLKAKLDYPK
>NZ_CP011271.1|WP_082838621.1|1031568_1032678_+|DUF1501-domain-containing-protein
MSETTPTRRDFLRTTVAGAAGFALAGAASGNANAPAALGNAKSCIFINMVGGPAHLDTFDPKPDAPSDVRGPFRPIQTATPGTHLSELFPQLAKLTDKFSLIRSMHHDAPPVHECGFQLLNTGRLFRDGPEWPNVGAVIDHRFGRKWSDTSSWMAMPNATIDTGISVSHGQGTGWLKLGGAPTIMHPLYHPTMPFDECCRFASVMDDLGLRFMTINQFPTVFDAPSWDCHADGGSLRTTLGDVRDTVAPSFDTAVARLLTDLEDRGQLESTLVVATGEFGRTPKLNSNGGRDHWAGCWTALVAGGGVKGGRVIGASDRIGSEPSARPVSPQELVSTVFHALGVPHNATIPGPDGAPVAVYPGAPVTELF
>NZ_CP011271.1|WP_052553152.1|1048820_1049273_-|IS200/IS605-family-transposase
MPQSFTRLHYHLVFSTKYRMPVITDEMRPRLWNYLGGIVREEGGVPVAIGGTADHVHLLVTLRQQPALSDVLRHLKAGSSGWVHDMFPEVDNFWWQTGYGAFTVSHSGIDKVAAYIANQEEHHKHRTFQDEFRTLLTKHGHEFAEEDLWD
>NZ_CP011271.1|WP_082838628.1|1049648_1050275_+|RNA-polymerase-sigma-factor
MAKPGAPPISRPIAGSDPAPDAPVVGPPTSADRPSDDTLVATFNQVRDELVSTLLYLLGNADDAQDAAQEAFLKCWRARSSVPDVQNLRAWIFRVGLNAAKDFQRSAWNRKSRPLPEDDVMLPTRDEAPGRVAEDQEALDRLRQAISQLRQDEKEVFLLRQNGDLTYEQIAEIRSAPVGTVKTQMRTALIKLRKVLNPAGATEEEPCS
>NZ_CP011271.1|WP_082838629.1|1050265_1050688_+|hypothetical-protein
MFVSTIRGTFAALFVVLCATPGAAAPVPAERAKAEKEQAAVAAKLQGEWLGGPCDGRLTFRADGTYEWRGAGPVPNVSRGKWAIRGDAQAPVLVWKCAEADDKELIGKTVEMPLVRLDGAVLVLKCAEPLEPRRFERVKS
>NZ_CP011271.1|WP_082838630.1|1050900_1055220_+|hypothetical-protein
MNCEHCQTLLLDHLYGLLEGSEAAEVDAHLANCPQCSDARAETARVQGLFARAAKSAFPNTKFEPPAPAPQKSHTRTPTLAAPSVPLSQAPADHQSGRMLRRLAVALPWAVAVAVLIAIPGTVVPVLNIHERAAVAQRSAEVADREADDAKLAVASAQNVRDGRLKEAELKLTTAEQGQAALLDKWMDAQKAAVEATTNRKLTIDVQKPATVQPGAPNDFFVVVRDERDVWASRRKMVAEVRSSDAVLYTQELDHEKRGNRHEIRLPASVWTKVKPDDDLTLVVAQVDEKTNVRTPIQEVRLAGPVFTTLLVTDKHTYRPGERLFFRSLTLDRVTLRPPQREQILRYDLVSGNNHFGRPLPGLVAMGCTDLVRVTGGANGRVEPIRTADGRPIRGVGCGEFVLPADLADGDYTLVLHELPQPSGGFTPTLPMPVTRTVKVRNGTADHYGKLIGFAGKSFCPGDTVEAWADLSFQEKPVADAEVAGVAVEVDGVTLDGVEVAPRTDAQGRARVRFALPEELTNGDVRLKVAFRAGGRSEMVADRVPVVGRRLFVEFFPESGDKIVAGVPCKVYVRATTPAGQPVDISGIITDGRETLATVKTLRDDGTPGANRGLASFTFIPQAGIRTWLKLDAPNTVYAPIVDGPVHTSSVALVGGAGAVAARTGFVLPETQLEGVVMSVPDTITAPGQPIRVHLRSVGGSRTLVVGAYIRGRLCDTQRVTVEPEQLTEVKLMAGTDPLTGGRGGVVRITAFEEMDPKDVKGGDEKPDLKPVAERLVFRRPGEVLNLALGVTPSLQTGFAQAAPQSTAKRVVAADDSVTCTISATDEKNNPVAAILWAAVVNTGAAPGAKDRTMPTHFLLAGDVKSPEELEFADFLLTDHKLAGEALDLVLGTQGWRRFAEQAKVAGKSSPPPPRNQELTRMMVQNGQYQVFAEPTAAREYRRIAETYAPLYESAVQAVGRARTSLKAAHEDTRDTVVVREAERVATTAARTADEKHERAEGAREPIRQFRSAVWYGVAGFAALALLCGGVAVARPQTRFPLGASTIGSFGLAAFLFVAAGWGHEVQAKPILQAEAARPVDSVFDSAADAPVAPQPHMKLTPQFDAATVVAAPTQLQNFGANKHDGPEKSSFAPPGTAVPMSGGSKVESFGGPPPKSAGFAPSPPNPPSGLPGAPPSIGRMPDPRGGYGGGGPGGPTTPVPLRPETRPEAKPGAPKTLAGGATGWNPMSRSGVTIGDLTQHRPMGTVGGFVGGPTVYNERVDSLRKDNDKVARYTSERQRVITESLDACLAARGAAGAAQDNMMAQTAQDASRVEVLALQQLRASATPTTPLVVREFAAPRPGSASFSDSMMDAPDTILWQPVIVLPTDGRTTLNFQLGNAPGGYRLIVAGHTADGRLGEARMVILTPSAQTVNAPTKLTPNGPAAPLAPAAPTVPPKP
>NZ_CP011271.1|WP_052553143.1|1055318_1056104_+|TIGR03000-domain-containing-protein
MKMRAFGLAVAACLVLPSIGSAQHVFLGVGVTHGYPYGPRVAPAWSYPGLYGGPFVGYPPPLRYGYGGFAGYGYGYPGFGYGYPGYYGFGYPYFGSPGRAGSVWSNGLSLYGPPVPVYGPVPGVFGNNDLVRQWRATPGFAGYGWVGIYAASPRPRHLNVSVWPTVEQFSSGPVAPVPAAKNGGSLILSVKVPQPTADVFVDGKKTAQTGTDRIFESPPLEAGQAYKYTITARWLERGQTVEMSREVTGAPGEVVRVDFGK
>NZ_CP011271.1|WP_082838631.1|1056200_1057613_-|DUF1501-domain-containing-protein
MHFPLSRREMLLRTANGFGAAALAALLEQDGRAVDTARSPNDPFAPKKPHFAAKAKSVIFLFMDGGPSQVDTFDPKPALEKYHGKPFPTKVEPTQFNNVGNTLASPWKFKKYGQCGMPVSDLFPHVGARADDLAVIRSMVANFSEHTNANYFWHSGHGQQGRPSFGSWVTYGLGSESRDLPGFVVLGSGLIPPGGADCFGNGFLPASYQGSIFRNGAHPVADITPPGGESAKTRTAKRDLLRKLDAAAKDKFGDSDPLDAAIANYELAFRMQTAVPELADLSKETTETQKLYGLDDPKTEIFGRQCLVARRLVQRGVRFVELLCPNLGHDRWDQHSNLKRGHEENARAVDKPIAGLLADLKRTGLLNETLVIWGGEFGRTPVAQGSDGRDHNPFGFSMWMAGGGTKGGTIYGETDDFGYHAVKDKVQVHDLHATALHLLGFDHKKLTYRFGGRDMRLTDVHGELIEKVLA
>NZ_CP011271.1|WP_162271585.1|1057862_1059578_-|DUF1559-domain-containing-protein
MRFALRTGGFAVVAALAAAVTALQPDAAPQSSSLSAAQPGDLPADLALVPADAVGFVHVGLAELWKNEVMDGFRKTWEKAGPKALSALDAQFIPAPSSISRGTAFVMLDDKKKPQAVGILAFSAAFDPAKVVKLYLPNNTTEKVGSKTVYRTPDHEVELYFPDDKHIVIGYGGSLNYYLSKEPAKDGPLTPAIKLAASGKVLVASADISALPIPPNAFKDVPPEGRAILQAKQLTLAVDLGADARVDLRATYADVAAAQGAEKAVKDLAELGRKELAKSKKELEDKLYDPKIKSPRPPSDLPEAMATVFGLGAINRLDEILTDPKFITRNNTELALAVPLPKELLVVGSGFVALGAALVLPAVQKVREAAARMQSSNNLKQLGLAIHNYHDANGHLPQDIVDKNGKPILSWRVAILPYIEQANLYNQFKLDEPWDSANNKPLSQVMIKTFVSPNGAFPDKPEFGLTHYRAVSGPGAAFEAGKKLKLTDFTDGTSNTIMVIETNDAVPWAKPGDYPFDPKKALPKINPVGAQKVFQALFGDGSVRAISTAVDEKTLKAFFTRDGGEVINEKE
>NZ_CP011271.1|WP_157470347.1|1059696_1060251_-|DUF1559-domain-containing-protein
MHNYHDANNAFPPAAVCDKKGKPQLSWRVLILPYIEQDALYKEFKLDEPWDSEHNKKLIAKMPKVYAMPGKSKPGDTDTYYRVFVGNGASFDWLMGTSLIGITDGTSNTFMCATGATAVPWTKPDELEFDPEKDNSKLIGLVVNGKAQVAMCDGSVRTLSKIPAKETLNALITRSGGEVIGNDF
>NZ_CP011271.1|WP_052553135.1|1061608_1062583_-|hypothetical-protein
MNTTAETALNTTSETANPATEATLDTTAETTLNAANTTAKTALDTATETTLDPATEATLDTANTAAEAALNAATDTANTTAETALNTTTETANAAADPATTGPTEVATDRRELRNVTADSTNPTNPTADPATNTTAQPTTNTADPTDPTTNPAAQPTTTETTAADPTAEATDPTATEATDPTATEATLNTTAAEAALNTAATEATLNTAALDTALVTLDTLVPGVTLVPDVTLVVPAVVPNVTQVVAQDRTRGAPGTLRYVREARGRAVPTVRRLRFQDLRQRQECENGQAKGSPNQRPVQRTDHVPPASVEVFRASPVRRGSR
>NZ_CP011271.1|WP_082838634.1|1063015_1063849_+|hypothetical-protein
MFGSLQRRLTWLACGLGVLALLPLSGVLKAQPPGGRYRSVASFSYVPPGAWRAPGGTQGNNQGNTGITGTAGNTGNTGVNGGNANGFTGQFGQNGFSGQLGQSGQLGQFGQFGQTGQFGQNGFNGQFGQSGNAGAGTSGSIMTYPTIGSYLGTGTGGFGQLGQIGNSGQFGQMGFSGQLGFAGQFGQQGQMGFSGQLGFAGQFGQLGQFGQGALGQFGQNGFNGQFGQFGQTGFGAAGQFSMFGQGAFGQFGQIGFGAGGQFGAGGKAFGFSGGSGY

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Crispr_ID: NZ_CP011271_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_3

1088588-1088677

Orphan

Consensus_repeat	Method
GCGGCCACCGCCACCACCGTACCCGCCGCCACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_3

>merge|NZ_CP011271|3|1088588-1088677|CRISPRCasFinder
GCGGCCACCGCCACCACCGTACCCGCCGCCACCACCGCTGCGGCCACCGCCACCACCGTACCCGCCGCCACCACCGCTGCGGCCACCGCC

>NZ_CP011271|3|3|1088588-1088677|CRISPRCasFinder
GCGGCCACCGCCACCACCGTACCCGCCGCCACC	ACCGCTGCGGCCACCGCCACCACC
GTACCCGCCGCCACCACCGCTGCGGCCACCGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_082838643.1\|1081435_1082359_-\|BON-domain-containing-protein	unknown	unknown	gnl\|CDD\|335963
NZ_CP011271.1\|WP_052553110.1\|1082761_1084486_-\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|223715
NZ_CP011271.1\|WP_082838651.1\|1091480_1091780_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366837
NZ_CP011271.1\|WP_052553083.1\|1096410_1099164_+\|mechanosensitive-ion-channel	unknown	unknown	gnl\|CDD\|366370
NZ_CP011271.1\|WP_082838654.1\|1093878_1094421_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082838644.1\|1084607_1085300_-\|VCBS-repeat-containing-protein	unknown	unknown	gnl\|CDD\|379232
NZ_CP011271.1\|WP_082838653.1\|1093433_1093757_+\|PilZ-domain-containing-protein	unknown	unknown	gnl\|CDD\|377796
NZ_CP011271.1\|WP_157469182.1\|1080934_1081192_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082838647.1\|1087223_1087703_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052553114.1\|1079757_1080537_-\|metallophosphoesterase-family-protein	unknown	unknown	gnl\|CDD\|223695
NZ_CP011271.1\|WP_082838646.1\|1085920_1086316_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082838650.1\|1089377_1090490_-\|acyl-CoA-desaturase	unknown	unknown	gnl\|CDD\|239583
NZ_CP011271.1\|WP_082838648.1\|1087816_1088437_+\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|277325
NZ_CP011271.1\|WP_082838652.1\|1091889_1092921_+\|biopolymer-transporter-Tol	unknown	unknown	gnl\|CDD\|274305
NZ_CP011271.1\|WP_082838645.1\|1085309_1085639_-\|VCBS-repeat-containing-protein	unknown	unknown	gnl\|CDD\|379232
NZ_CP011271.1\|WP_082838655.1\|1094541_1096236_-\|TolC-family-protein	unknown	unknown	gnl\|CDD\|224455
NZ_CP011271.1\|WP_052553103.1\|1086483_1086873_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052553099.1\|1089095_1089350_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052553096.1\|1091075_1091336_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082838656.1\|1099181_1102757_-\|protein-kinase	unknown	unknown	gnl\|CDD\|270916

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_082838643.1\|1081435_1082359_-\|BON-domain-containing-protein	gnl\|CDD\|335963	pfam04972, BON, BON domain. This domain is found in a family of osmotic shock protection proteins. It is also found in some Secretins and a group of potential haemolysins. Its likely function is attachment to phospholipid membranes.	1.31319e-07
NZ_CP011271.1\|WP_082838650.1\|1089377_1090490_-\|acyl-CoA-desaturase	gnl\|CDD\|239583	cd03506, Delta6-FADS-like, The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases are required for the synthesis of highly unsaturated fatty acids (HUFAs), which are mainly esterified into phospholipids and contribute to maintaining membrane fluidity. While HUFAs may be required for cold tolerance in bacteria, plants and fish, the primary role of HUFAs in mammals is cell signaling. These enzymes are described as front-end desaturases because they introduce a double bond between the pre-exiting double bond and the carboxyl (front) end of the fatty acid. Various substrates are involved, with both acyl-coenzyme A (CoA) and acyl-lipid desaturases present in this CD. Acyl-lipid desaturases are localized in the membranes of cyanobacterial thylakoid, plant endoplasmic reticulum (ER), and plastid; and acyl-CoA desaturases are present in ER membrane. ER-bound plant acyl-lipid desaturases and acyl-CoA desaturases require cytochrome b5 as an electron donor. Most of the eukaryotic desaturase domains have an adjacent N-terminal cytochrome b5-like domain. This domain family has extensive hydrophobic regions that would be capable of spanning the membrane bilayer at least twice. Comparison of sequences also reveals the existence of three regions of conserved histidine cluster motifs that contain the residues: HXXXH, HXX(X)HH, and Q/HXXHH. These histidine residues are reported to be catalytically essential and proposed to be the ligands for the iron atoms contained within the homolog, stearoyl CoA desaturase.	1.12482e-45
NZ_CP011271.1\|WP_082838644.1\|1084607_1085300_-\|VCBS-repeat-containing-protein	gnl\|CDD\|379232	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella. This domain of about 100 residues is found in multiple (up to 35) copies in long proteins from several species of Vibrio, Colwellia, Bradyrhizobium, and Shewanella (hence the name VCBS) and in smaller copy numbers in proteins from several other bacteria. The large protein size and repeat copy numbers, species distribution, and suggested activities of several member proteins suggests a role for this domain in adhesion (TIGR).	4.72125e-07
NZ_CP011271.1\|WP_052553083.1\|1096410_1099164_+\|mechanosensitive-ion-channel	gnl\|CDD\|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	2.50135e-27
NZ_CP011271.1\|WP_082838651.1\|1091480_1091780_-\|hypothetical-protein	gnl\|CDD\|366837	pfam01844, HNH, HNH endonuclease. His-Asn-His (HNH) proteins are a very common family of small nucleic acid-binding proteins that are generally associated with endonuclease activity.	8.65145e-06
NZ_CP011271.1\|WP_052553114.1\|1079757_1080537_-\|metallophosphoesterase-family-protein	gnl\|CDD\|223695	COG0622, COG0622, Predicted phosphoesterase [General function prediction only].	1.23128e-24
NZ_CP011271.1\|WP_052553110.1\|1082761_1084486_-\|GAF-domain-containing-protein	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	6.75594e-38
NZ_CP011271.1\|WP_082838653.1\|1093433_1093757_+\|PilZ-domain-containing-protein	gnl\|CDD\|377796	pfam07238, PilZ, PilZ domain. PilZ is a c-di-GMP binding domain which is found C terminal to pfam07317. Proteins which contain PilZ are known to interact with the flagellar switch-complex proteins FliG and FliM. This interaction results in a reduction of torque generation and induces CCW motor bias. This domain forms a beta barrel structure.	0.00231346
NZ_CP011271.1\|WP_082838648.1\|1087816_1088437_+\|metallophosphoesterase	gnl\|CDD\|277325	cd07379, MPP_239FB, Homo sapiens 239FB and related proteins, metallophosphatase domain. 239FB (Fetal brain protein 239) is thought to play a role in central nervous system development, but its specific role in unknown. 239FB is expressed predominantly in human fetal brain from a gene located in the chromosome 11p13 region associated with the mental retardation component of the WAGR (Wilms tumor, Aniridia, Genitourinary anomalies, Mental retardation) syndrome. Orthologous brp-like (brain protein 239-like) proteins have been identified in the invertebrate amphioxus group and in vertebrates. 239FB belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	9.14427e-28
NZ_CP011271.1\|WP_082838652.1\|1091889_1092921_+\|biopolymer-transporter-Tol	gnl\|CDD\|274305	TIGR02800, Protein_TolB, tol-pal system beta propeller repeat protein TolB. Members of this protein family are the TolB periplasmic protein of Gram-negative bacteria. TolB is part of the Tol-Pal (peptidoglycan-associated lipoprotein) multiprotein complex, comprising five envelope proteins, TolQ, TolR, TolA, TolB and Pal, which form two complexes. The TolQ, TolR and TolA inner-membrane proteins interact via their transmembrane domains. The {beta}-propeller domain of the periplasmic protein TolB is responsible for its interaction with Pal. TolB also interacts with the outer-membrane peptidoglycan-associated proteins Lpp and OmpA. TolA undergoes a conformational change in response to changes in the proton-motive force, and interacts with Pal in an energy-dependent manner. The C-terminal periplasmic domain of TolA also interacts with the N-terminal domain of TolB. The Tol-PAL system is required for bacterial outer membrane integrity. E. coli TolB is involved in the tonB-independent uptake of group A colicins (colicins A, E1, E2, E3 and K), and is necessary for the colicins to reach their respective targets after initial binding to the bacteria. It is also involved in uptake of filamentous DNA. Study of its structure suggest that the TolB protein might be involved in the recycling of peptidoglycan or in its covalent linking with lipoproteins. The Tol-Pal system is also implicated in pathogenesis of E. coli, Haemophilus ducreyi , Salmonella enterica and Vibrio cholerae, but the mechanism(s) is unclear. [Transport and binding proteins, Other, Cellular processes, Pathogenesis].	2.10323e-24
NZ_CP011271.1\|WP_082838645.1\|1085309_1085639_-\|VCBS-repeat-containing-protein	gnl\|CDD\|379232	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella. This domain of about 100 residues is found in multiple (up to 35) copies in long proteins from several species of Vibrio, Colwellia, Bradyrhizobium, and Shewanella (hence the name VCBS) and in smaller copy numbers in proteins from several other bacteria. The large protein size and repeat copy numbers, species distribution, and suggested activities of several member proteins suggests a role for this domain in adhesion (TIGR).	7.13038e-05
NZ_CP011271.1\|WP_082838655.1\|1094541_1096236_-\|TolC-family-protein	gnl\|CDD\|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	1.05024e-06
NZ_CP011271.1\|WP_082838656.1\|1099181_1102757_-\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.97396e-47

>NZ_CP011271.1|WP_082838648.1|1087816_1088437_+|metallophosphoesterase
MRIVCISDTHGWHDRADVPEGDVLVHAGDITRHGSLKDVEDFDRWLGTLPHKHKIVICGNHDWCFQETPMEARVRLTNATYLEDSGCEIEGLKFYGSPWTPCFSDWAFMLPRGSELAAKWAQIPNGLDVLITHGPSEGILDRNRTGECCGCRDLLYRVLEVKPRLHVFGHIHEAAGRADIAGTIFLNASTQMGKGRGVVIELGNGA
>NZ_CP011271.1|WP_082838647.1|1087223_1087703_+|hypothetical-protein
MTEAEQATDKDKLHAGTALTTLVFYAKHVVWFVVAFGAAYTATFLAFWFGSGVAAEVREQLPSPLPALQIPKLPQIIRALVLLIGPGIFAGIVAVACPRWWKSLIAGPGFGVLGGTLFYLSPAERLEASVIIPVAWTIAGLIGSAIVIVRRAFTVRAAY
>NZ_CP011271.1|WP_052553103.1|1086483_1086873_+|hypothetical-protein
MFRIATATALLLTGASFSTAADDVAPVLKSGTWYVDVRAVVMGTRYEYTFRKDGTFKVEITNDVANPPATGTWKIEAKDGKQVLVLDTKGKQGHALPSESEVSFDRAKNVLVSRDKGGAEVVLKFRKGR
>NZ_CP011271.1|WP_082838646.1|1085920_1086316_+|hypothetical-protein
MGLTIATTLLVLLAKESQPAPTKTYVTGFVAALQERIEDDEHFRYQALCVTWWWRTSDPGYLRNYISAREFQEWRRGLREEKAKIRKLHVESLVLQELAERAKRKAEEAEREVERVKREVLEEQRQQKKTP
>NZ_CP011271.1|WP_082838645.1|1085309_1085639_-|VCBS-repeat-containing-protein
MRIRSRVALGAIGLVLVAVGAPRQSHADPRPAERLTEFGPPKVILDGSEFAARLKPHYADFDGDGKIDLLVGAWDRLLVYRNRGTNAEPEYAKPTWFDEAVPSGRIPAG
>NZ_CP011271.1|WP_082838644.1|1084607_1085300_-|VCBS-repeat-containing-protein
MFTPQFGDFDGDGRADLVSGSNCCDPWTVHLFLRKADGTFAARQEITFVRSDMTPQQRAWVMRGHSQPHLLDWDRDGRTDLVLADSQSWKLLVGVGPLKGKSEVTVRPFDLPEVADRKPYDFQFADWDGDGVFDVLFAGGYLSADKRWLYDLYWCRNTSREGQPRFEKPVRLLTAPAQSDGWGYEGFTVADRGRAGHQDLVLSVSKDWQPKPKPEKGWTNKSQLVLFQRK
>NZ_CP011271.1|WP_052553110.1|1082761_1084486_-|GAF-domain-containing-protein
MPRLIVIRGVDEGKQFELTGATVTIGRHSANAVSLHDTQVSRRHLEVRAGAHGYELVDLGSGNGTLLNGQPVQVAPLRSGDAITIGQSVLMFTVGRNEMPALGNELTERVRLRAQPDQDLNSAIVRTVAADAGSQILARPSVATDWVRTRLASLAALYETAEVVSHILDVDQLLDAVMNLVFKSVDADHGCFMVRDESGRLIPKAVRYREGTNRQEELAVSHTIVDHVIKEKQGVLVSDVHNDDRFSGVESLHRHNIREAICVPMKGRREVVGVLFLDTQSTLKQFVTRGLETGKFTEDHLHLASAIAHQAAIAVEESRYHEALVNAERLAAVGQTIAALSHHIKNIMQGVRFGADMVRTAIKESDTDLLGKGWKLVERNQSRIDELILDMLSYSKEREPAVEPTDLNKLCEDVLEIIRGRATDRGVAIEWRPGVGVSVVPCDTEGIHRAALNLVSNAIDALEDHPSAKLSVQAILEPDGTWAKIIVMDNGPGIPTDKLEDIFRPFVSTKGSRGTGLGLPVSRKIVREHGGDILVQSVIDKGSKFTIRLPMKSAFTGDANAATGLFPVLPPLEE
>NZ_CP011271.1|WP_082838643.1|1081435_1082359_-|BON-domain-containing-protein
MFAHLLSSTTLRTLAGFTCVAGTVGVGTLFAIDPLPPGAPVSSPVPLVAPAAKPVSISDVALARAALAAFDADPVLKDAHVFVSVVDRGAVIGGPVTSESVKKRAEAVVRAIPGIESVKNTCFIEADPDPLMRAVADRMKPGTKPTISSTPLPGVSIPPAAPEGYIPPVPPPQPTDLVASVQKTVVAQHPTSLGPPVVGLLGAPVAPHTVAKVPPTPTPTPTPSAPSTAPGALTGSAGAKPSDVLTAVAAIRATDARFAKLTAELKPDGGLFVSGSAAQITDVVDFVAEARKVSGVVRVAVDPKLVK
>NZ_CP011271.1|WP_157469182.1|1080934_1081192_+|hypothetical-protein
MREVAAAFAATQARIARRFAEVPVEESAAVVDDELRGLYHGLFVIFDGGTALADKGLVQIRSDDGTAFDRFLHEICFSYWPKADA
>NZ_CP011271.1|WP_052553114.1|1079757_1080537_-|metallophosphoesterase-family-protein
MRVLVVADIHGNRAALEAIREPFDVCLCVGDIVDYGPEPAWCVDWVRQNATYCVRGNHDHGVAQNVDIQGAGGFRFLTSVTRPIAVATLSGDQRRYLAELPTSRMFTLNGKRFLLVHATPRDPMDEYAPADPAFWYPRLAGLKVDYVLTGHTHVPYTLRVRNTLVVNPGSVGIGRDGNPHASYAIIDGDDVQLKRIEYAIEETVGAMEATVRDATARLMLTDVFRTGGLPTKWLLRNGSLSNGNGNGNGNGNGNGKIAH
>NZ_CP011271.1|WP_052553099.1|1089095_1089350_-|hypothetical-protein
MAERLTAKEQVQSMLDRGWVWRDDYSDVLVHPQDYSLSATYDRATGTLTFSPELLKALDQIIPTPPNRNPRYWRDEQKSNSPKK
>NZ_CP011271.1|WP_082838650.1|1089377_1090490_-|acyl-CoA-desaturase
MSLRSEFLVGAQAPPPKFPKDEAGFLNELKRRADAYFAETGCSERDCWRMYLKTAVILAWLATSYALLVFAAPTVWLAAPLSISLALAISAVGFSIQHDGGHHAYSQFAWVNRLAALTLDLIGASSYMWKWKHVVYHHTYPNVAGQDTDIDVGRVARLAPQQPRLWFHRWQHLYLWPLYGVTASAWHLYGDFRDVIAGTIGAHRVPRPTGWDLVVFLTGKAVSIGLLLVIPMLVHSWWVVLVFYAVVTAVVGVVLTVVFQLAHCVGEAEFPQPIEGGRRMGDTWAVHQVQTTVDFARESRVLCWLLGGLNFQVVHHLFPRVCHIHYPALARIVEATCHEFGVRYTAHRTLWGGITSHFRWLRELGQLRQI
>NZ_CP011271.1|WP_052553096.1|1091075_1091336_+|hypothetical-protein
MSDELTIDFLEWLTESGRVRLRYQSQEGRSDELWLGAKQVTPSDLARVARHWSGGGNLSPETAGVLVGLALEKVSTSLGREWHSAS
>NZ_CP011271.1|WP_082838651.1|1091480_1091780_-|hypothetical-protein
MNEPKPMPCGLCGRGFPKPALTQHHCLPKSKGGTSDDVAMICSQCHGMVHATYTNATLAAVYPTIEALRKAPELVAFIKWVRKQPITRRKRNKERRDKL
>NZ_CP011271.1|WP_082838652.1|1091889_1092921_+|biopolymer-transporter-Tol
MNVLLLSLALAPAAQPDDWKTAETAHLKNIKQLTTDFVRAGEGYFAPDGTKIIFQAEEKDTGNPFYQIFIMDLKTGKATRISPGIGRTTCGYFHPSGKKVLFASSHGDPDAKKHQEAEYKQREEDKKKGVRRRYSWDFDPHMKIYEANLDGTGLKCLTPDAKVYTAEGSYSADGKRIVYSAGNAGNVQLFTMGTDGTNAKRVTDAPNCYNGGPFFSPDGKKIVFRADRKEKDRLQLYVINSDGTGEKALTADDKWVFWAPYWYKDNKHIIYTGADHSNPLAPPNYDLHWMDTESGKKARITFAPGQDVLPVFSPDYTKVMWTSSREGGKAAQIYIADFTPPKE
>NZ_CP011271.1|WP_082838653.1|1093433_1093757_+|PilZ-domain-containing-protein
MADAKDRRAAERMAVNAGTGCGFVGPVAENFGPAKVRDVSLDGIGLVLTRRVEIGTLLALTLTNATQKMSKTVLVRVAHVTASHGGFLVGGTFAEPLTYQELTSFVM
>NZ_CP011271.1|WP_082838654.1|1093878_1094421_-|hypothetical-protein
MWTPPPEHPLRRMFAGLAEHAFFSHLGVADPPLTDYLSVLLTRFIHNDDVYRLRGATGQPLTELSEMVVEAERLPTGGKTQRDYYRHIGDFALFWTGIYPEAVERIRSRMCKDAFVNYTAQGKRGYMLTSRLEEEQHHDAEAGLFRRLSDQFEVCAIGLRKVREEWEELSPSPPTGGLIS
>NZ_CP011271.1|WP_082838655.1|1094541_1096236_-|TolC-family-protein
MERFRRALFAWAVAGLGTATGCATDAASDGPRETVRAQQPTRPAPRSSTPVPPASLASGKQPATNSAQTTEPAPLPINLATALKLSNARPLDVQIAAQQVTSAAAIYDRARVLWLANVSLGADYPANSGSLPTTGKANRNALTVGTGSNALFAFSDAIYSPLAARQEQRATSPVNDPAIATADAYFALQQARGDLAGAIAAESRAEEFVKSATDATDARAELGRRKQAVTTARERERTANSELARALGLPPATRLEPAEPAFLPIAVIDPVINLDELVPVALTTRPELAGNRALVRATLARLKQESLRPLVPSLAVRSVPTSARDPETSGERFDIAPQQLREFVTVAFSDKPQTNEGRDELEGATIDLFRAQDRIATEVATAFAQVRAAAQRLNAAEPALKAALERAQKNASPQEIASALQAFSQANTEFFAAVAEYNRAQFRLYCVLGHPNQCLANPVPQAPLAAMPLSPTPEMKPSAQPAPLASVPQVAGEMPAAPIAAALTPVPPPASVVPPAPNTAQPLPVQEWTSVPVPGANRLPTVIEEPPLPSTPVRPPVVVPESGN
>NZ_CP011271.1|WP_052553083.1|1096410_1099164_+|mechanosensitive-ion-channel
MLHIRILSAGVAFLSALCLALPGNGRSDEKAPPPKSVLVDREQVRKELEAKLTGRAPAEVVAFVEQLAREWVVRKGAYELAHRRFTSQAAEVSKDRQRVDDLKAPAPVPLVLRSADVEAALKAEQAVVDHHASRVKHLEAWNGAAAALAVAGADFDRAARAADDHLFAMRTASAFAAKVGAGKLPDAVEAKQLDDAAARIKALGSEVRAALEKATSDSAGVEKQLVDARAASDAAAAKLEALKGAQADTLAAFRFEEQARSMAPAQLVDEFAKTRKSLAEKTGAISGDAGDYKKAVASASDARHSLNAVKEPPPPTRAEVPTSLEQTTRALAGVEAYLTARVRNSAEREEKANALISALDELERRAVAYSTTLDDARRLAAQVTAFATETERRVGNGDLDAAQVPAGFGDTNRAQPDGELRAVTLTIQQLRQEREQLRKPDPDAENIKALTGHLLARVDERLNLLADLRALAHSYAVPYKDRPEAEQKRLDQRVTERVNGEAAEWDWLLAFDRSKASASAAELLSADYRELIDFDDQADTLKRQKEALENLVDLGRREAADIAKLRTVLEKYEATSESTRTWDEWLRLRTASGGLKAEETTYRDEVSRLNAVSLATARRVEALTGNSATDANKVTEQTKLPAGGGEIGKARAELRAARIRGLRETGIRIGIVLLCAFILPRVMIFVLGRAIRGGTNEAGSPSPVLAALRRVLKVGAWAVALVLVLNILGYDVTALVMALAIGVLALALAARPMIADVLGSVAIFAERRFKVGDVVRLGTGEPARVVGLTWRSTALKNATGLMLSVPNRKVTELTVENLSRGGETYDAIAVTVSTDKDAGKVVTVLRGAVGQCKNVSADNGVAVVRYSQKGNVKVVEYRFWWFLKDYEARTKTRDEVFARIALGLSQEDMAGIEVTLG
>NZ_CP011271.1|WP_082838656.1|1099181_1102757_-|protein-kinase
MFVRPEAQVEPIPGYKLLDRLGAGGFGEVWRCEAPGGIFKAVKIIHGDLRSKDSDLVRYAEQELKSLKRVKQVRHPYLLALDRFDIIDGRLMIVMELADCNLWDRFRACREAGLVGIPRDELLQYMAEIAEVLDLFNDQFQLQHLDIKPQNLFLLYNHVKVADFGQVKDLQGLMAQVTGGITPVYAAPETFDGVITRYCDQYSLACVYQELLTGARPFDGSSMSQLLMQHLSLPPYLDPSPPADRPALARALAKKPEDRWPSVSAFVRALAGAPPLSGISAPGRFNTSESETPNLISVPPAPGSVFSSLSLTDDTPQRGETYGPVFTPAPPELSGDGPLQPALVLGLGNAGLRVIQRLRFDLNERYGRSGLTPALRTLYIDTDSEAIDEANRERPADRLAKLDADEVFAAKLNRAGHYLKPRFNGRSLTEGWFDAQLLYKIPRAPQTLGIRSLGRLAFLDHYRALMTKVQADLDAAVAPDALLLTEARTGLKRRTNRPRVYITGSLAGGTSGGMFLDLAFAVRNRLKRMGYERPEIIGLFVLPPADATLTPPQALGNTFAALTELNHYSRSDTQFTAHFDERSGYVKEQDAPFTRCYLLPGSASGVVPQSGVGITPPPGTPNPGSRARFGSGGVQKPGSRIVALGALGSQRTPDPGAAAAALKPYGDAAERIRLDLFSPIGRCTDETRAAEEVTEHPGPVTVSAFGVATFDWPRAEVVSRTAASVGREILRRWAAPDLKRVREVMPGIAESRWTQLGLDPETIIERLQRAADQSAGRRVDTLVESVTEPLVPRGWLNRLPEPTQIHVALNDLNRLLGPPASSVKRPQTALEEEVARAAADAGSAFALDLRTLAPVLVDDAEFRLAGTEELFRQFLATTDRLIDRYTHLAVELDSKAVAGFECLSRYAHYQKGMWKPSTAELTDALRQYPRARFQAITFRQMVTAYQIVRDVLSMQIADVAVARQRMATASASVPDAPPEPPASLRRLMPPGCPTIGDAVNRFLKVLSDADLTDIDRRVQSVLEPETGGLFQVCLNSSSGVEDVIAVVFEETRAHLDQRLGEVGLASMFAERFRTPQQAERAIEQAYQEAEPAWAGNGPWAASEVSVLSCPGGTSGEALRELARRAIPIAALPITDSCDDLTIYREWTSVPLAALPHLGPAAAAAYDAIPDANQCSPHTRLDITAWFDVDSK

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Crispr_ID: NZ_CP011271_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_4

1334356-1334542

Orphan

Consensus_repeat	Method
ACCCGCGGCCCTTGCGGGCCGGGTTC	CRISPRCasFinder
CGCGGCCCTTGCGGGCCGGGTTC	PILER-CR

3 spacers

The CRISPR arrays of NZ_CP011271_4

>merge|NZ_CP011271|4|1334356-1334542|CRISPRCasFinder,PILER-CR
ACCCGCGGCCCTTGCGGGCCGGGTTCGCCCAACCGGTGGGCCAACGAGCCGCGACCGCAAACACGAACACCCGTGGCCCTTGCGGGCCGGGTTCACTCAGTGCCTTGTCGCAGGCGAACCCGGCCCTTGCGGGCCGCGGGTCCAGTTCCCTCCGCAACATTACCCGCGGCCCTTGCGGGCCGGGTTC

>NZ_CP011271|4|4|1334356-1334542|CRISPRCasFinder
ACCCGCGGCCCTTGCGGGCCGGGTTC	GCCCAACCGGTGGGCCAACGAGCCGCGACCGCAAACACGAAC
ACCCGTGGCCCTTGCGGGCCGGGTTC	ACTCAGTGCCTTGTCGCAGGC
GAACCCGGCCCTTGCGGGCCGCGGGT	CCAGTTCCCTCCGCAACATT
ACCCGCGGCCCTTGCGGGCCGGGTTC

>NZ_CP011271|4|1|1334427-1334542|PILER-CR
CGTGGCCCTTGCGGGCCGGGTTC	ACTCAGTGCCTTGTCGCAGGCGAA
CCCGGCCCTTGCGGGCCGCGGGT	CCAGTTCCCTCCGCAACATTACCCGCGG
CCCTTGCGGGCCGGGTTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_162271599.1\|1323326_1323830_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377585
NZ_CP011271.1\|WP_052560650.1\|1334718_1335381_+\|RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|224511
NZ_CP011271.1\|WP_082838784.1\|1339435_1340191_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_157470359.1\|1342156_1342399_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082838787.1\|1345735_1346221_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082838778.1\|1328201_1329248_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|119407
NZ_CP011271.1\|WP_082838776.1\|1323841_1325404_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|274350
NZ_CP011271.1\|WP_082838783.1\|1335444_1336488_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_157469202.1\|1329365_1329713_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052560597.1\|1325475_1326867_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NZ_CP011271.1\|WP_052560652.1\|1336749_1338318_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|225116
NZ_CP011271.1\|WP_082838781.1\|1332362_1333091_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|316258
NZ_CP011271.1\|WP_082838786.1\|1342800_1343712_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226098
NZ_CP011271.1\|WP_162271601.1\|1340272_1342111_+\|redoxin-domain-containing-protein	unknown	unknown	gnl\|CDD\|239267
NZ_CP011271.1\|WP_082838782.1\|1333462_1334260_+\|polyprenol-monophosphomannose-synthase	unknown	unknown	gnl\|CDD\|133062
NZ_CP011271.1\|WP_082838779.1\|1329910_1330396_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052560653.1\|1338514_1339261_+\|DUF4058-family-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082838780.1\|1330521_1332060_-\|YifB-family-Mg-chelatase-like-AAA-ATPase	unknown	unknown	gnl\|CDD\|223679
NZ_CP011271.1\|WP_162271600.1\|1326976_1328014_+\|DUF3500-domain-containing-protein	unknown	unknown	gnl\|CDD\|378789
NZ_CP011271.1\|WP_082838788.1\|1346259_1346817_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_162271599.1\|1323326_1323830_+\|hypothetical-protein	gnl\|CDD\|377585	pfam05991, NYN_YacP, YacP-like NYN domain. This family consists of bacterial proteins related to YacP. This family is uncharacterized functionally, but it has been suggested that these proteins are nucleases due to them containing a NYN domain. NYN (for N4BP1, YacP-like Nuclease) domains were discovered by Anantharaman and Aravind. Based on gene neighborhoods it was suggested that the bacterial YacP proteins interact with the Ribonuclease III and TrmH methylase in a processome complex that catalyzes the maturation of rRNA and tRNA.	2.11458e-16
NZ_CP011271.1\|WP_052560650.1\|1334718_1335381_+\|RNA-polymerase-sigma-factor	gnl\|CDD\|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	2.4633e-42
NZ_CP011271.1\|WP_082838778.1\|1328201_1329248_+\|hypothetical-protein	gnl\|CDD\|119407	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.	2.5281e-33
NZ_CP011271.1\|WP_082838776.1\|1323841_1325404_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	6.94704e-38
NZ_CP011271.1\|WP_052560597.1\|1325475_1326867_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	1.2588e-177
NZ_CP011271.1\|WP_162271601.1\|1340272_1342111_+\|redoxin-domain-containing-protein	gnl\|CDD\|239267	cd02969, PRX_like1, Peroxiredoxin (PRX)-like 1 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a conserved cysteine that aligns to the first cysteine in the CXXC motif of TRX. This does not correspond to the peroxidatic cysteine found in PRXs, which aligns to the second cysteine in the CXXC motif of TRX. In addition, these proteins do not contain the other two conserved residues of the catalytic triad of PRX. PRXs confer a protective antioxidant role in cells through their peroxidase activity in which hydrogen peroxide, peroxynitrate, and organic hydroperoxides are reduced and detoxified using reducing equivalents derived from either thioredoxin, glutathione, trypanothione and AhpF.	5.08249e-43
NZ_CP011271.1\|WP_052560652.1\|1336749_1338318_+\|HD-domain-containing-protein	gnl\|CDD\|225116	COG2206, COG2206, c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms].	9.84756e-73
NZ_CP011271.1\|WP_082838781.1\|1332362_1333091_-\|hypothetical-protein	gnl\|CDD\|316258	pfam13719, zinc_ribbon_5, zinc-ribbon domain. This family consists of a single zinc ribbon domain, ie half of a pair as in family DZR, pfam12773.	1.21584e-05
NZ_CP011271.1\|WP_082838786.1\|1342800_1343712_-\|hypothetical-protein	gnl\|CDD\|226098	COG3568, ElsH, Metal-dependent hydrolase [General function prediction only].	1.20559e-20
NZ_CP011271.1\|WP_082838782.1\|1333462_1334260_+\|polyprenol-monophosphomannose-synthase	gnl\|CDD\|133062	cd06442, DPM1_like, DPM1_like represents putative enzymes similar to eukaryotic DPM1. Proteins similar to eukaryotic DPM1, including enzymes from bacteria and archaea; DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. This protein family belongs to Glycosyltransferase 2 superfamily.	3.06757e-89
NZ_CP011271.1\|WP_082838780.1\|1330521_1332060_-\|YifB-family-Mg-chelatase-like-AAA-ATPase	gnl\|CDD\|223679	COG0606, COG0606, Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP011271.1\|WP_162271600.1\|1326976_1328014_+\|DUF3500-domain-containing-protein	gnl\|CDD\|378789	pfam12006, DUF3500, Protein of unknown function (DUF3500). This family of proteins is functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 335 to 438 amino acids in length. This protein has a conserved GHH sequence motif. This protein has two completely conserved G residues that may be functionally important.	2.19555e-100

>NZ_CP011271.1|WP_082838782.1|1333462_1334260_+|polyprenol-monophosphomannose-synthase
MPATGAIDPTPAQTAPAASPRTGEPRLLISLATYNEAGNIAALIADIHKVVPHADVLVIDDNSPDGTGRIVAELAGSDPRIQVLHRPGKLGLGTATLAAMKFAMARDYDYLLNMDADFSHPPRYLPGILAGMSKNDVMIGSRYVHGGGTENWPLPRRVISQSVNALVRLTFRMPVKDASGAFRCYRVSMLRDAELDRVRSRGYSFQQEVLFRCYKSGAKLGEYPILFENRRAGVSKVNKKEAARSMSMILYIGLRNVFGLEQRRV
>NZ_CP011271.1|WP_082838781.1|1332362_1333091_-|hypothetical-protein
MPTVTEIPCPNCDTTLKVPDTVLGKKIKCKHCGHPFVAEEPEPARPAKSAKPAKPGGVGVQAKKPEPKKEEPKPADAPYKFQDDDDDDGGAKPNPLGVIAESDVARCPHCAQELDPPDAKVCIHCGFNNVTREKAEQKKVWAPEFGDYMNHLGPGIIGLIICVALIVLDAICLLNMRDWMTGTFLESDQADPTDPSRKAMLVKPGAFITLIWAATIMPIIRTGRFAIKRLAIDNKPMERLKK
>NZ_CP011271.1|WP_082838780.1|1330521_1332060_-|YifB-family-Mg-chelatase-like-AAA-ATPase
MLAQLNTFALLGIDAVPVQVEVDTSPAQQPRTVIVGLPEMAVRESIHRIERALVNLGYRLPTGRTVVNLAPADLRKDAGAFDLPIALGLITSLGQIVADRIETFAIVGELALDGTVRPIVGALSVAMEARARGISKLIVPSANAREASVVREVEVYGVGSLAEAVGIVTGLAPIDPVSPPTDDIEANLNKYAIDFADVKGQEFAKRALTVAASGGHNVLMLGSPGSGKTMLARRLPTILPPLTPNESLETTRVYSAVGKLQPGEALLCTRPFRSPHHTISDAGMVGGGGVPQPGEISLAHHGVLFLDELPEFNRRSLEALRQPLEEGRVTISRAAHSTTFPADFVLCAAMNPCPCGFLGDPKKPCKCAPIAVEKYMGRVSGPLLDRIDLHIEVPPVPFEDLSKPGDGTGSAAMREQVFAARAIQAQRFGSKAGGLNGRMTSKQIRTYCVLDADGQTTLKEAMEALGLSARAHDRILRVARTIADLAASERITQDHVAEAIGFRALDRKLWER
>NZ_CP011271.1|WP_082838779.1|1329910_1330396_+|hypothetical-protein
MFAALYAITAAASLTSSPVMESLQPPKVWKDKLVSILTIKDTVDEGTEGSKGSTFPPSGGTTYNTLTYPGTLEVTDPGESGEGVIKYSFKARIRKKNYEAGAEVGTHDSNINGVITAKYSFTFSGKVLIDVKDIKYESGNEHNAGRCIYNRIKNTNGATVK
>NZ_CP011271.1|WP_157469202.1|1329365_1329713_+|hypothetical-protein
MLTGLPAVIEDVIVITTGVLEGVGQDRHQVKGTILVNAFGKGANDRGKPRRFECDRTKGVAEDVTEQTGLKTTFRLLAGFVKSNSPQSPARIHSAARSGTKIGSIVPQSHTLPTS
>NZ_CP011271.1|WP_082838778.1|1328201_1329248_+|hypothetical-protein
MLRGSLLPLLALVSIIAPSSAFAADPPLKGAVIVVDPGHGGQGYSKSYTGGTRGVHSKMTEGELNLKVGLELAKILQDQGATVHLTRVGDHRLSPEGSSNSDELHARIDFFEHHECHFFLSVHHNAGAASATGHTALYKHNAADDTLYEAIARGVNEALDGAVPGPKRALIKGSYHILRETPIPGTIAESGFMTNRDFDDLSTRPEYPKKEAAAIAKGAVKYWTTHQAALVALREKLAKDRAAKPRDPKTYTAIALNPAHKERMKALLDTVAPGGKYEAAKAGEYVEAFRKVIATDPKALFTVKAESTGERIKLTGEADQKLHNQLIDMLVAMKLYGIVNEVRVPKAK
>NZ_CP011271.1|WP_162271600.1|1326976_1328014_+|DUF3500-domain-containing-protein
MTRVRISVIALTFAAVVSAALVGTSAPATTGSRMTASATAFLGSLSPELKKKASFDFTDPHRAAWFFTPRQDGEKKFTRKGARLEEMTAEQKKAAMELLKSGLSAKGYEQATTIIGLENLLLELEGPKSAMTRNPSWYFVSVFGEPSSTGKWGWRFEGHHLSVNYTLDKGEVVAGAPILFASNPAEVKDGAKKGLRPLPEIEDHVRALIKSLTEEQDKIAKQPKAFPEIKEGQAKADVGAPVGITADKLTADQKATLVKLLQAYAGRMPDELADTEMKKVKATPDTKLFFAYSGSPKPGEGYTYRVQAPDFVVEFLNVQADSAKNQANHIHSAWRRLPIDFGLSE
>NZ_CP011271.1|WP_052560597.1|1325475_1326867_-|sigma-54-dependent-Fis-family-transcriptional-regulator
MSAPAEPLQILVIDDDKTHAETVAESLERRGHACTIATGGKAGVAKLEQTPFDVVLTDLKMADLHGLEVVERCKQLRPDVDVYVITGFAEIETAVEAMKRGAAHYLRKPLNLAELRAVVENSAKRVGTLRDLRRQIDEKFGFEGVVGNSPNMQKVLKALRAYAPSSASVVILGENGTGKELVARSLHTNSPRKAKPFTAMNCAALNENLLDDEMFGHEDGAYTGSKGARKGRFEHAHGGTLFLDEIGDMPLALQAKLLRALENGEIVRIGANDPIKVDVRIIAATNKDLQKEVDAGRFRQDLYFRLKVGTIKLPPLREHREDVPQLVSHFLKDFARRDNKPVPKVSPGVWKAFEGYDWPGNVRELRNLLDSMMVLDLDGELTPDDFPDDAGVKPPGAGGTTVSSGPDHLIGRPLDEVERFYMEKALELTGGNREEAAKMLKISERTMYRKLQEWKKESEKPAE
>NZ_CP011271.1|WP_082838776.1|1323841_1325404_-|tetratricopeptide-repeat-protein
MASDTPSEILILVRRGHAYTRRGEYGKAVEAFSGAVDLEPADAELYFHRGNALAAAGKHDDAVADFTQAIELRPDYAEAYHNRATAHVDSGDLDSALADYTRAIELDPDDPDAVNGRAAVYSRQKNYDAAFVDYEVAAKLAPNTFRVFFNRGNAYSALNQHEEAVVDYGTALRINPRHGRAYLYRAMSLDALGRTDEALSDLSTALRLQPMSTEAFWQRARVYAERDEHAKAVSDFTWVLKIDPKHSDALNLRGVSYAELEDHVKAISDFTKAITIDPADAAPWFNRGLSHLRLRNTQPAIEDFTEVIRLTPDDPAPFVQRGYAFHELRDTARAIEDFTQAIALRPDSARAYFGRALANRRGGDLHAALSDASAVIERNPQSDSAYNLRASLRYQLGDFAPALADHLKAAEIDPNDAATLNHVAWVRATCPQDDLRDGSAALRDALRACELTNHEAPGYVDTLAAAYAELGRFEDAVKWQQKAVELVPDASKPDYETRLALYRENKPFRDRIEIPPPPPV
>NZ_CP011271.1|WP_162271599.1|1323326_1323830_+|hypothetical-protein
MTFLIDGYNLMHAVGLVNRKTPCAQFERARTRFLDWLADGVKGRAVTVRVVFDAQDAPAPSLEMTHRRVRVRFAYQRTADDVIEELVAVEQKPHTVTVVSNDSRVREAARRADCGVASCQEFTDWLISTVPEYSGVVAPPQEPDKPELTPDELNEFLEAFSKPKPKP
>NZ_CP011271.1|WP_052560650.1|1334718_1335381_+|RNA-polymerase-sigma-factor
MGIRAVLDPIRLPPDTDEQLLARLRAGERDVFGALVRRYERELFGYLRRYLGDDDLADDVFQNTFVQVYLKIQQYEPGRPVRPWLYAIATNQAIDALRRRNRRADQRADAVTTSDEDGQNRPLFELLPTPGDGPPESADRAEQRELVRAAVDRLPDLLRQVVVLAYFQGLKYRDVADALDIPVGTVKSRLHAALARLTEDWNASQESGTGTQEAVQIPNV
>NZ_CP011271.1|WP_082838783.1|1335444_1336488_+|hypothetical-protein
MSDADLIDYLFDVLDPADRSLVAARISADPHTAARLEQLRASVAPVLATAEAEREDMPAPPPGLALRALARVAQHVVEHEPRAPEPTGSDAISAFLREFSSSPPTELEFGSGTRAKVPGAPRTPRPAPPVSDGPDPQPSRRFRADLLVAACIAFVGFGLVSSGIAKARQQQRIYACQNSLRTLHVGLAGYADSDPQGRYPQIGTPAHPTADTFAASLSDQGHLPAGFRPGCPAAADYIAYAYTLGFRTPNDEILGLRRADAMAPAGEEHDLMPIAADFPTASAAPFAGPVSPHSGCMNVLFVGGNVRPTTSALVGPGGDDIYRNLFGQVSAGASRTDAVLGRPGDRP
>NZ_CP011271.1|WP_052560652.1|1336749_1338318_+|HD-domain-containing-protein
MKRPLRLRGISGEIKGQVWESDSLLRAGRLGSLEIVLDDSSVSRRHAEVRRGDDGWFVRDLESTNGTYVNGVRIGQGDQPLKARDIVQFGKVAVIVELVDATVDGPPSNQHVVAAAVSSFDEGLRRIAFDRNHMPRAGEQMFALLRAGHHFVNTQSEDQLLDAVLNDAVSVLEAQRGAIVLAESDAPEPKMRLRALAVGQGEPPGRFHYSKKLTQRCFASGVSLLYSTLTDAEESKLTQSIADGAMASVLCVLLRTPRKRLGVLHLDRSFWQNPFTEDDLHLADALAAHVSAAIESAQLLRRQKEQFLKTVTVLAQAVELRDDYTGNHTQRVTRYATMLGEKLELPDDQLELIKIGGPLHDIGKIGIDDSILRKPGRLTGEEYECMKTHTTKGAEILSSIPEMGPIIPIVRSHHERWDGAGYPDGLIAEEIPLLARIVAVADAFDAMTSNRPYHENKKGKPPSWAFAEVERQAGKQFDPMCATAFLGIREEIVRAMAELLPGSELEDPEPVTVTGYVHDPRG
>NZ_CP011271.1|WP_052560653.1|1338514_1339261_+|DUF4058-family-protein
MPLYDHFHSPLSLRKSWESIHSAWAVMMVTRLNGALLSARFESEPKVHHGSQIEIDLAAYEEDRNLPMFGANGHNGGGVATHPQTYTPPVAALAGEVVMADADTFEINVYKQEGGWKLVAAVELVSPRNKDRSTARRAFATKMASYLQQGVSVVTIDVVTERNANLHEDVANALRLPDTFDWSSPTGLSAMCYRLLRVDGKERLEVWPHQLTIGASLPTVPLWLEPNLAVPLELELTYTSTCESLRIG
>NZ_CP011271.1|WP_082838784.1|1339435_1340191_+|hypothetical-protein
MPLRDHFRPPLSNDTPWSVFHGNWATKIVDRLNGDRLSAKYKAQSGRHFGAQIEADVATLERTERGSLFAGLSESGGGVATAEVFSPPATTLSATVGFTDPDLFEVKVYRGAGGWELVAAIELVSEANKDREESRRAFVVKCGNYLQKGISVVVVDTVTTYSADLHDKLCDLIDGADSLRWTSPTGLSVVVYRPTRVTDGTNSALAIEVTPYQLNTGFELPTVPLWLGRDLAVPLELEFTYTQACRSLRIV
>NZ_CP011271.1|WP_162271601.1|1340272_1342111_+|redoxin-domain-containing-protein
MALLFELIFTAAIAALPVPEFELRDTTGATIRPPTGPDARPMVIVFLGTDCPMARLYSVRLKEMTGRFPAGSVTFLAINANAGDDLSSMAAFLREHPLAFPYVKDADGHVAELLGASRTPQAFVLDAQRRIRYRGRIDDQYAAGGKNRGAPTREDLAEAVRDVLAGRPVSVPRTECTGCVIDKPRRTAPPPGVTYARDIAPILAAQCRTCHRPGEIGPFSLLSYSDAVAHAGTIAEVVETGTMPPWHADPKHGRFRNERLLSDDQKRLIAEWVRLGCPEGRPLPSEPAPAPTDWHIGTPDAVFRIPRDFVVPAEGVVEYQHFFVDPGFTTDRWVNAVEVRPGNRRVVHHCSVYLQPPSAAGKDEMFETGALGSFFLVGFVPGVGPVQLPAGMAKRVPAGWWLHIVVHYAPVGSPQTDRTEIGLRFLDATAVRKEVATKLLLVEDLAIPPHTANHRAERTWTAPQDVLLLSLLPHMHVRGKSFRYAAEYPDGTTEILLDVPRYDFNWQHLYELAEPKRLPAGTVIRCTAVYDNSADNPFNPDPSVTVRTGEQTRDEMFNGYFDIALADQDMVTERAAIEQKRGRSQQIGAGALVLAGLWGTRLWRKRRALQSV
>NZ_CP011271.1|WP_157470359.1|1342156_1342399_-|hypothetical-protein
MRDIFGNPFRPVVFSASWRTDTVVSLAQQMYESRDFGAMPILADALQDAGCNNDDILTHCRTPGEHVRGCWVVDLVLGKE
>NZ_CP011271.1|WP_082838786.1|1342800_1343712_-|hypothetical-protein
MSRRKRRVLWVLAALGSFVLLVVGLFALNGLVLADRQTPRMRHFADVHVAPTRSAPGEVTFISYNIAKGFAHKGGVRFESREFVENKLKRMAEVLRAEQADVVFLSEALTELSACDIDQVAYLARECGLPFVATGENYNLGLPFYRVVGGNAVLSRTPLTPVANFDLAGRQPFWVSKNNRRALFVSAEFGGKPVLMGALHNDSFDMRNNTVQMQQLLDFIGDRPAILAGDFNNRPKDRSIALVRDSGKFAGEFDGAPSFFEGKRAERLDYILVPAGWELIESRVIPDDTSDHRPVVGRFKVKL
>NZ_CP011271.1|WP_082838787.1|1345735_1346221_-|hypothetical-protein
MLVYESADQLLAEPDARRFLHVVILNAIRDKATQLEVRFGDAGGLLYYRVEGRDWELAPPSDDVYPLLKDTVRDAAQLVSPERPELTVIAGVPGARYEPLEAGWLTYQLGGRWIDLAVRIDPREPFGYIRFDIDDAEDFVEAAGEALADYATRLATEEDEE
>NZ_CP011271.1|WP_082838788.1|1346259_1346817_-|hypothetical-protein
MGSESAAPPERAFAYWNGWHAVGCSVLFFGLLGSIGVSLFPAGYEKVQSGQLPTGIALMVMGVFGVPTLLMSFWSLWTGVRDTLSPPRVRVTTTSLFLPTGARGEPPQDEHGEPISHEPPHPATIPLAAIRSVRRAGPVHNLVLEVLHDASAVPLRLSQHMMRKTDFDDLEAVLRAAIPGAFAAP

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Crispr_ID: NZ_CP011271_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_5

1792507-1792620

Orphan

Consensus_repeat	Method
GTGGCTCGTCTCCGCAACCCGGGTTGAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_5

>merge|NZ_CP011271|5|1792507-1792620|CRISPRCasFinder
GTGGCTCGTCTCCGCAACCCGGGTTGAAATCCCGGGTACGAGAGCCCATTGCCGGCCCCGCATGGTGTTTCGGGCGCCACCGGGCGTGGCTCGTCTCCGCAACCCGGGGTTGAA

>NZ_CP011271|5|5|1792507-1792620|CRISPRCasFinder
GTGGCTCGTCTCCGCAACCCGGGTTGAAA	TCCCGGGTACGAGAGCCCATTGCCGGCCCCGCATGGTGTTTCGGGCGCCACCGGGC
GTGGCTCGTCTCCGCAACCCGGGGTTGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_082839081.1\|1771969_1773100_+\|SIR2-family-protein	unknown	unknown	gnl\|CDD\|238697
NZ_CP011271.1\|WP_082839092.1\|1803841_1807780_-\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|106506
NZ_CP011271.1\|WP_052559247.1\|1784705_1785377_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_162271632.1\|1788415_1789912_+\|phospholipid-carrier-dependent-glycosyltransferase	unknown	unknown	gnl\|CDD\|224720
NZ_CP011271.1\|WP_082839093.1\|1809121_1811851_+\|glucosidase	unknown	unknown	gnl\|CDD\|367389
NZ_CP011271.1\|WP_052559264.1\|1795556_1795946_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225253
NZ_CP011271.1\|WP_082839086.1\|1786256_1788371_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP011271.1\|WP_082839089.1\|1790947_1792363_+\|dihydropteroate-synthase	unknown	unknown	gnl\|CDD\|272997
NZ_CP011271.1\|WP_082839090.1\|1796916_1797852_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082839091.1\|1799132_1801679_-\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP011271.1\|WP_052559265.1\|1796018_1796897_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082839083.1\|1774590_1775715_+\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP011271.1\|WP_082839085.1\|1777431_1784382_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380149
NZ_CP011271.1\|WP_052559238.1\|1773292_1774246_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|197318
NZ_CP011271.1\|WP_082839088.1\|1790037_1791381_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133022
NZ_CP011271.1\|WP_082839084.1\|1775758_1777090_-\|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|223936
NZ_CP011271.1\|WP_052559274.1\|1801899_1803813_-\|response-regulator	unknown	unknown	gnl\|CDD\|237425
NZ_CP011271.1\|WP_052559270.1\|1798406_1798619_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052559280.1\|1808076_1808574_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052559258.1\|1792999_1794157_+\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_082839081.1\|1771969_1773100_+\|SIR2-family-protein	gnl\|CDD\|238697	cd01406, SIR2-like, Sir2-like: Prokaryotic group of uncharacterized Sir2-like proteins which lack certain key catalytic residues and conserved zinc binding cysteines; and are members of the SIR2 superfamily of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation.	2.95934e-34
NZ_CP011271.1\|WP_082839092.1\|1803841_1807780_-\|PAS-domain-S-box-protein	gnl\|CDD\|106506	PRK13560, PRK13560, hypothetical protein; Provisional.	7.00855e-86
NZ_CP011271.1\|WP_052559258.1\|1792999_1794157_+\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	5.76064e-29
NZ_CP011271.1\|WP_162271632.1\|1788415_1789912_+\|phospholipid-carrier-dependent-glycosyltransferase	gnl\|CDD\|224720	COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane].	2.48249e-38
NZ_CP011271.1\|WP_052559264.1\|1795556_1795946_+\|hypothetical-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	5.39721e-05
NZ_CP011271.1\|WP_082839086.1\|1786256_1788371_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	6.05133e-151
NZ_CP011271.1\|WP_082839089.1\|1790947_1792363_+\|dihydropteroate-synthase	gnl\|CDD\|272997	TIGR00284, Uncharacterized_protein_MJ0107, dihydropteroate synthase-related protein. This protein has been found so far only in the Archaea, and in particular in those archaea that lack a bacterial-type dihydropteroate synthase. The central region of this protein shows considerable homology to the amino-terminal half of dihydropteroate synthases, while the carboxyl-terminal region shows homology to the small, uncharacterized protein slr0651 of Synechocystis PCC6803. [Unknown function, General].	1.64127e-51
NZ_CP011271.1\|WP_082839093.1\|1809121_1811851_+\|glucosidase	gnl\|CDD\|367389	pfam03200, Glyco_hydro_63, Glycosyl hydrolase family 63 C-terminal domain. This is a family of eukaryotic enzymes belonging to glycosyl hydrolase family 63. They catalyze the specific cleavage of the non-reducing terminal glucose residue from Glc(3)Man(9)GlcNAc(2). Mannosyl oligosaccharide glucosidase EC:3.2.1.106 is the first enzyme in the N-linked oligosaccharide processing pathway. This family represents the C-terminal catalytic domain.	2.11945e-05
NZ_CP011271.1\|WP_082839083.1\|1774590_1775715_+\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	5.57123e-95
NZ_CP011271.1\|WP_082839085.1\|1777431_1784382_-\|hypothetical-protein	gnl\|CDD\|380149	NF012181, MSCRAMM_SdrD, MSCRAMM family adhesin SdrD. Features of this protein family include a YSIRK-type signal peptide at the N-terminus and a variable-length C-terminal region of Ser-Asp (SD) repeats followed by an LPXTG motif for surface immobilization by sortase.	5.44955e-22
NZ_CP011271.1\|WP_052559238.1\|1773292_1774246_+\|hypothetical-protein	gnl\|CDD\|197318	cd09084, EEP-2, Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; uncharacterized family 2. This family of uncharacterized proteins belongs to a superfamily that includes the catalytic domain (exonuclease/endonuclease/phosphatase, EEP, domain) of a diverse set of proteins including the ExoIII family of apurinic/apyrimidinic (AP) endonucleases, inositol polyphosphate 5-phosphatases (INPP5), neutral sphingomyelinases (nSMases), deadenylases (such as the vertebrate circadian-clock regulated nocturnin), bacterial cytolethal distending toxin B (CdtB), deoxyribonuclease 1 (DNase1), the endonuclease domain of the non-LTR retrotransposon LINE-1, and related domains. These diverse enzymes share a common catalytic mechanism of cleaving phosphodiester bonds; their substrates range from nucleic acids to phospholipids and perhaps, proteins.	2.53613e-34
NZ_CP011271.1\|WP_082839088.1\|1790037_1791381_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|133022	cd04179, DPM_DPG-synthase_like, DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily. DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. The UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. This protein family belongs to Glycosyltransferase 2 superfamily.	1.96424e-27
NZ_CP011271.1\|WP_082839084.1\|1775758_1777090_-\|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	gnl\|CDD\|223936	COG1004, Ugd, Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane].	0
NZ_CP011271.1\|WP_052559274.1\|1801899_1803813_-\|response-regulator	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	9.82916e-111
NZ_CP011271.1\|WP_082839091.1\|1799132_1801679_-\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.46469e-58

>NZ_CP011271.1|WP_082839089.1|1790947_1792363_+|dihydropteroate-synthase
MSAPAPLPRILFITGKLAEPALRRVVEELAPKAAFEPHVAVLPITVAALMTTNWVSRHLPPLPPDLNRVILPGFCRGEIEDVSRAVGAPAERGPTDLRDLPEFFGKQSAPRDYGKYDIEILAEVNHAAKKSLDTILREARRYRDSGADVIDLGCDPGPAWGGVGDAVRALRADGFRVSIDSFNSDEVDAALAAGADLVLSVNGTNVEHARRWHAAYPRVEVVAIPDTPSDSDSLERTVDVLRGIGIKHRLDPILEPIGFGFAASLGRYVDSRRRFPDAELMMGVGNLTELTDVDSAGLNVLLAGFCQELGVRSVLTTEVINWARSSVKEFDLARRLVFHAVREKVLPKRLEPGLVMLRDPKVPEQGEELLQELARRVTDRNYRIFAERGELHVINGSTYLRGTDPFALFEQLAANDPKLDPAHAFYLGYEFAKAVTALTLGKAYTQDQALRWGFLTVPEASHRNSGDHTRG
>NZ_CP011271.1|WP_082839088.1|1790037_1791381_+|glycosyltransferase-family-2-protein
MAKPTTPHDGVTVVIPVHNAAAQLEKMLPAWGLVLGKQNRPYQIIVVNDGSTDGTAATLEKLAPRVSHLQVLTHDARRGFGACLRTALAETTQPLFMYAGIDNQYTPNDIRSMLERIELRDEIFGKQPDLISGFRAGQPRPALVKVISFLWKLFWRVFAGLPIVDSPPWYGWGQWWYKNRASWVFGVPLADVNSEFKLYRTAFLKRVPVQSDGDFVHVELVAKATFLTSIMDEVPLTPKTEPLPPLASVSADRSKVFRDPKFAFNTPAEVKPPEAGNPPTAPDVPATEANAGEPSPPVLQCPRHECARASPAHSVHHRETGRAGPSARRGRTRTEGRVRATRRGAPDHRCGADDDQLGLAPPSPVAPRSQSRDSPRVLPRGNRGRVARGGRSRRARTDRPPRPARVLRQTVRSARLREVRHRDSRGGEPRREEVARYDLARSPALSR
>NZ_CP011271.1|WP_162271632.1|1788415_1789912_+|phospholipid-carrier-dependent-glycosyltransferase
MLRWFPFVTSAVPVLALILLFFFQLGARDLVSSHEARAAQNSQRMLDTGEWGLPTLFDEQRDLQKPPGYYWLGAVAGYLDGGRVSPWAARFPAAASSILAVLLVYGFLRRESGKTTALVAAVALGTANHFITIGRTARIDVPLTCAVTVALFAFYRGTTAGVGTRVARREGWFVLSALAAGGAVLLKGPVGLALIGSTAVAFLIAERFATAPADRARLPLLSAIVGVIVVALVAVPWFVWAQHATRGEFVRVFFWHHNVERFAGTSEALASHPWWYYGPRFAMAFLPWTLPLVPLVWWGLRSGVWKEDRAFRLGVVWLVVMVAVLSASRFKRADYLLPAFPGAAIALGCAAERWLTSRADARSAVRAKWGFGVLVAGALAVCPVMWIVVEPAENARQEKRPFAAAIREYAPKPQTILLFRAESHLLAYHLGAPLHTLVEWGELREVLAVPGPHAVVMPPEYVDEAERITGRKLVPVATLADFTSVRPPRPLVCLRTAE
>NZ_CP011271.1|WP_082839086.1|1786256_1788371_+|ABC-transporter-ATP-binding-protein
MRNFRRSVWFSWPYRQRLVASVFCALVVAVLWSVNLGAIYPVLKLLSSGKNLQQWVDEEIAEQQKQREIRAREVANLNFALATLETKPDTPEREKQKRNYSADLARATDLQDYHASWDYRYQWLRAKLIRYMPTDRFEAFLWIMVGVLVCVVVKGVFEFLHESLVGWVTNRTLFDLRNSFFRRVVRQDVRQLSSAGTTDLMARFTNDTEQIGSGVKVLYGRVVAEPLKAVACFAAACFICWQLAVTFVVVVPLALYVLMRVSKAMRKASKKALQRMSAMYKILNETFGGIRAVKGFTREAHERRRFRQANYEFYRKALRLVNIDAFTNPAIEVLVVLSVGLALGAGVYLVVSQSTHIGIFRMCSQPISFETLLQFYVFLAAIADPVRKLSSVYTKLQGAEAASARIFELYDREPTIGGNADGPRLTAVKKRIEFRHVCFAYNPAADTPTLDNVSLTVKAGETIAVVGGNGCGKTTLLALLPRFFDPDSGAVLIDGVNLRTAHLRSLRKLIGVVTQDTQLFDDTVLANIAYGKRGATRDEVIAAAKQARAHEFIEKKEGGYDALMGTAGSNFSGGERQKVALARAILRNPQILILDEFTSAIDMQSEIDIHDALKEFVKGRTTFLITHKLHTVPEIADRVAIMDAGQLLDFGTHAELLTRCESYRRLFESVQMWKTDAAAPGGTKESAPLTETPKPSHPTQRGAA
>NZ_CP011271.1|WP_052559247.1|1784705_1785377_-|hypothetical-protein
MSRFRNVLRVLAAVLVGTAIFGAPTQAQAAFAIQYSIDGGTFITINDGDSVAGLKITASSYTDPTVSLLDLHVTGTFIPSSETHTIVIQATVTDLTTAPAPQTLTTKFTGGTSTGTATFTGQSWVDDANNLFGIPGTFTTGSIVPGNGITPDFVGSFTGNVPYSLTTQITIATEGRKEVNLGADIDNVVTPTPAPAGIVLVLSGLPLLGIARLRRRNLAAPVA
>NZ_CP011271.1|WP_082839085.1|1777431_1784382_-|hypothetical-protein
MTPTWKTFLSRLHSTISGTGRRPVRTRRLKPLAIEQLEDRLVPSFALRFSTNGGATFGAAVTDGSINDTDPLAGTIGVNIGAISIKASSLGSTSAASTTLNLAVTGTAAASATVGHDIVVQASLDDLTTAPAPQTLVYSFTGSTPSGGTVTAQTWVDDGNTLFGTTGDTTGAKIIPASGSLVVSDTVPYSSTTQLRLVFKNSTPINLSLNNLNTITASPEQKAEIHGTKFEDVNGNGTREGGESGLLGWTIQLLDTNDNVLATTLTAVDGSYSFTNLTPGIYRVREVNQAGWTQITANPGDIGTVSGSNITGIDFGNFKNITIAGTKYTDITGDSFSSDDTPLAGITVNLFKNGALVATTTTASDGTYSFANQGPGNYFVQELVPTGYQQTGGNAGYTIVATSGLVSSSNNFDNFQLAKITGKKVNDITGDGITSDDTGLGGVTINLYQNNASGALVASTTTAADGTYSFDNLAPGTYFVQELVPAGYQQTAGNAGYTVTVGGTGVQSGGTATGNNFANFKQVTITGTKFTDITGDSFSSDDTPRAGVTINLYQNGSFVTSTVTGADGTYKFENLGPGNYFVQELVPAGATQTGGNAGYTIAATSGLNSADNNFDNFYHGQITGKKVTDLTGNGLSADDTGLGGVTVNLYKATSTLTLIASTVTAADGTYSFGDLDLGTYFVQELVPSGYVQTGGNAGYTITVGPGGVVSGGTSSGNDFANFQKGSITGTKYTDLTGNGLSGDDTGLGGVTINLYSGNSTAGTLVASTVTAANGAYSFGDLAPGTYFVQELVPAGATQTAGSAGYVVVIGQGGVGSGGTSSGNNFANFYRGQITGTKFTDKTGDGITSDDAGLGGITINLYQNNASGALIATTTTASDGTYSFGNLDLGTYFVQELVPAGSTQTAGIAGYTITVGPGGVTSGGTSAGNNFANFKNITIAGTKYTDITGNSFSSDDTPLAGITVNLFKNGALVATTTTASDGTYSFANQGPGNYFVQELVPTGYQQTGGNAGYTIVATSGLVSSSNNFDNFQLAKITGKKVNDITGDGITSDDTGLGGVTINLYQNNASGALVASTTTAADGTYSFDNLAPGTYFVQELVPAGYQQTAGNAGYTVTVGGTGVQSGGTATGNNFANFKKITISGTKYNDITGNSFSSDDTPLAGVTINLFKDGGTTPVATTVTASNGTYSFDNLAPGTYFVQELVPAGSVQTGGNAGYTIAATSGLNSTGNNFDNFKKVSVTGTKVTDKTGNGFTSDDAGLGGITINLYSGTSTAGTLVASTTTASNGTFSFSNLAPGTYFVQEVVPNGYVQTTGTSGYAVTVGGTGIQSGGTSANNNFANFQKVKITGTKFQDMDGCGFGSDDVVLGGVTVNLYSGTSTAGTLVATTVTAANGTFSFEGLAPGTYFVQEVVPAGWTQTGGNAGYVVTVGGTGVQSGGTASGKNFDNYKKPNPGIDIEKTTNGPTNSNTTAPDYDNEDAVDGPGVPILTPGSTVTWTYKVTNTGDVAFTTSQIAIVDDNGTPGLTSDDLSIANGKITFLSVQTGDSDNILEPGEVWLYKATGTVQDFSVPVAGSSVSFDFSGNSPVSGTAGNVRTFTSSGVSVNASAFSRDKTTGAWSTAYLGSYGGGLGVTDTSESGSSNSHTVDNYGRDNYVLFEFSESVVIDSAFLGYVVGDSDLTVWIGTKTGAFNNHLTLSDSVLASLGFTEVNLGGSSTRTANLNAALLAGNVLVIAAKTGDSDDNFKIETLCLQKVKPGVYENKATVTVPGDSDSDLSHYKNPPAAVGGSISGTKYLDVSGNGLNKTAGTYSPADTPLAGVTIYLDLDNDGRLDAGEPQTVTDANGNYLFTGLSSKTYYVREVVPAGFVRTGPALSDYYAVAVATGKSYTGYDFANAEACDTCVENTITCVSYTIYHTDGTRETVSDLRGRTREGDLITVTFKVNVPTGQTQQVTFVSYTAPGADFDANTASQQKIYDLDTDEFGPGTHTLTVRVPNCYYQVDFVCGFAIDKLGPANSNIFYTPQKRLLSADNGGDDCCDNAGTISGYKFNDADADGVWDNGEKGLSGWVVYLDGNNNGYKDSWETATVTDANGYYKFNNLAAGNYRVREVQQSGWVQSAAPALVALTTGQNKTGVNFGNVAGSLVSGCDTASIDFWNCSSGQNLIKSLNGGSTKTALGTWLANNFSKLYGSSSSYNLSGKTNAQVASYFQTLAGKTDKLEAQILATALAVYATDSDLAGGTYARNYGFKVTTTGIADEFYNIGTNGALFGVANGGVRTVWQILVAANNSATSGLAWNGNSTTRNAARTLFAGLNDVGGIG
>NZ_CP011271.1|WP_082839084.1|1775758_1777090_-|UDP-glucose/GDP-mannose-dehydrogenase-family-protein
MKVAIIGTGYVGLVTGTCLAESGNDVVCVDNNPKKIAVLQQGGIPIYEPGLQELVARNARDGRLAFTPDLAAAVRAARLVFIAVGTPQSDEGDADLTAVFAVADAIGEALKDAPPGPPGTRVVVTKSTVPVGTNAKVAERLAAKGCAHVDVASNPEFLKEGAAIEDFMKPDRVVVGARRPEAAEVLRELYAPFLRTERPFLVMTPESAEMTKYAANAMLATKISFINEMANLCDRLGADINDVRKGIGHDQRIGFQFLFPGPGYGGSCFPKDVEAIIAMGRRTNLPLELMRAVDAVNDAQKLVLFEKVRAHYGDGLAGKTLAVWGLAFKPRTDDIREAPALTLIDALLEAGTQVRVHDPEATANVRAIYGDKLHYADRPYGALEGADGLVVVTEWAEFRNPDFEVMKRLLAQRVIFDGRNVYDPRMLRQFGFTYYGIGRGARV
>NZ_CP011271.1|WP_082839083.1|1774590_1775715_+|serine/threonine-protein-kinase
MALLAPERLADIDGLRARFASEEQLTTELVRRKWLTPLQGRWLLRGHGARLFVGSYVLVDRIGEGGMGQVFLARHRSFGRPAAIKVLRPDRLDNKRGRARFLREVRALGHLDHSNVVHAYDAGLIGRACYLVMEYVPGPDLARVLAAGERLPVGHSCEYARQAALGLHHMHERGLIHRDIKPGNVSLAEGGRTVKLLDVGLVKERMNPDADGEVLTQAGWLVGTADYAAPEQVLNARNVGRRSDQYSLGCTLYHLLAGEVPFPGSTPVARALRRVTENVRPIHELRPDLPAGLSEVVGRLLAREPKGRFPSARAAAEALAPFATPLVTAAAETTVHISTCPTLPTLPTLDGPTATESELSTPADAPATAPRSGQ
>NZ_CP011271.1|WP_052559238.1|1773292_1774246_+|hypothetical-protein
MLALGLWGVLRFADSWPVATVVMFAPLHLVALLPGALLVVAAAFHRRALRTLVPAFVITVGPVAEFCVPWAGASADGVPTGARLRVLTCNAHYARMSAAPLEALVADARPDVVVLQEWNSKNRSEVLTAPEWHTHRDSGHFLASRYPIRRVEPLGNQSAGTQGSVTRYALDAPAGAVTLFSVHLASPRDGLSEVAKGGTFGFDNILANSELRWIQSRNLADWAGRVDGPVVLAGDFNTPPHSDIFRQVWGEYENAFASAGWGWGHTFIVRVAAVRIDHVLVGGGGRASACWVGPNIGSPHRPVIADVAWPVGGLKAP
>NZ_CP011271.1|WP_082839081.1|1771969_1773100_+|SIR2-family-protein
MCWDSASHAAAQAERVRRADWPTDLTEQLRAEAQRLAAHALRGELALFLGAGVSIAAGLPSWGGLLDELAVRAEMSREERAALAELRNALDQATVIERRLKARGGSIGRTVASALGPRRHYALAHALLAALPVREAITTNYDQLFEDAWALSDPDGLSVLPGAIKPDARRWLLKMHGCLSDPDRVVLTRSSYTRYDEQLPALSGMVQAFLVTRHVLFVGFSMTDDNFHRIVDAVRRLRGEHRPPGHFGTALSLGAGGLAEMLWDQDIRRVRMADVPETMANFAAPEAARRLEVFLDYLVSRTRDAAHLLVGERFDSLLTPGERQLRDALVRFVKDVTGADASAIRGTVAWPQIERLLRGLGLEPPDGALVSGSGGE
>NZ_CP011271.1|WP_052559258.1|1792999_1794157_+|TlpA-family-protein-disulfide-reductase
MRLLCAAALSLSVGLWVAYAQDKKPADGPKTDRAEKFAALKKKFEDENKELATQLSKVENPGDARAIQGEMKELVLLTAGKAFEIAKDDPKDDVGFDAAAFVVQIAGRIGANNEDVDKATQMIALHHAASAKVRDLLVPAMRLGEPGDKLLKAVSEKATDKDTKGVATFIRGYKIAQAIEEEEDEKQIALMVKDATAMLELAAKEAPNAKINPSAPKSPTVGDLATKEIENLKAVTSVVVGKAAPEVESMTLDGKKVKISDYKGKVVLFDIWATWCGPCKAMIPHERDLVKKMEGKPFELISVSADNKKETLEKFLEGEKMPWTHWWDNGPESPVLKKYRVRAFPTLYVIDHTGVIRHKWVGNPGNDKVDAAIEELVKAAIKAKG
>NZ_CP011271.1|WP_052559264.1|1795556_1795946_+|hypothetical-protein
MGRKKVDASAVSLTSLRAARLYRLLTLLRSGPQTRAALLRRLKLDVRGFYRDLESLRALGIEVNVGDDTKYTLVGEVDDALAKLPFPDPGLNVRDALQLSIGNSSAHRKLKQRVNSFLNGPRGGPNKPR
>NZ_CP011271.1|WP_052559265.1|1796018_1796897_-|hypothetical-protein
MSTILLAALALAPAQPAGDKHDDLNPLFKRLMDPGLEVGPNAKAKFPAPTMADGLTADKQKAIIKSAIGTDYNYDEFVRDSVVAPQVMKIRDLEPADKTAPARAVDVWFVVYGDFKLLEDEKFLDKLIGAGKSSGGGKGGPLPAAELTKRNIEIKKGDEKREGYGTIEFDFLEKVRLRATGHAMWSRNGESVLAAAEVDPRFRDDKEFPNEWRSITKTGGQTKVGNPNPWGGAAMYLKITKLAEPAGALFVEQHIVFAEPTGWFDGANLLRSKLPLVVQDNVRTMRKEFKKK
>NZ_CP011271.1|WP_082839090.1|1796916_1797852_-|hypothetical-protein
MRVRKALLALTIVALAALIAVGAAIRLLRPNPVTPAWVDEYDVTASAPETIAPGTVIERAAPKGWSHLVIKSLPRVRPSEVEHVPSLPIVGRDLTVRMVAWMFTAFTADVVQEHQGDQTRYRLRAIGLGLGTNVNGRDVVITTATAGQHGADMNAIKRQVLDTGYRIQKQAIIPVHGPSFALLDTPVISRCGNKHRTIRYRYALLVDTKTGSLDVLLWLLGGDGGECNDLTRAVWIEPNCIDPAELVPDPEEFKGNIPSDLSFAVDKLPPYRLEMAVPPELRELVGRTKFTPDEARALEAGLRKLTAEARP
>NZ_CP011271.1|WP_052559270.1|1798406_1798619_+|hypothetical-protein
MSFRARLSVFALEQRENPSVSVLDPIGIETPPLTEPVPPPAPTTPVVVAPTPPTDPLLGTNPIYQIPLVP
>NZ_CP011271.1|WP_082839091.1|1799132_1801679_-|protein-kinase
MHPTTVFPSNDPRFVPAPEPARPAPGAEDQPTMRVPAALPAPAEAFPVVTPPPRGRLAPLSNAPLGIANLSGSDWSSEWDDDGESMFPGARRPPRVGDTVLGFKLVGELGRGAFARVYLAHQESLANRPVALKVTLRPTHEAERLARLQHTNIVPVYSVHTDGPVQVLCMPFLGKVTIADLLRVYRSDPSRVAGRRSTVARGARTTLTTDSKSVPASDGRSGAPRVPVWTWDSADPPPIVGDPRTVVQALVQLAEGLAHAHERGILHLDLKPANVLLADTGEPMLLDFNLSFDAARPDRELVGGTMPYMAIEQLLDMRNRGAGALDQRTDLYALGAMAFEMLTGSVPFPPTPKGLRDIDGQVALRRQGPPALRPLNPAVTPAVEAIVRKLLAAEPEDRYQSAEQLRTDLERHLNDQPLRYARETSVTERLGKWRRRNPGLTVRLMAAGLIGLALGLGGILHQRAEATARVGAVEQARVTRAALDTVRIDLILYGDKTTHERGEKRAGELLAAYGLPGDPDWQKRPEVSRLTETERGALTADLGELLLLLAQARWQGFETRPESERRERAAQAWKLNRAAQACFGASAAPAALDRQAALIAPAVGEVFEAPNPAKAPGARTEFIEAAFALMSGRYATAVPLLDRAIADQPAHGAAQFCLAYCRQQLGQYTRALERYDVARVLLPKDPRPALQRGAIYGLCKKPALAEAEFTKAIDLDPGYAEAYRARGLTRYRLARTDEARPGRAAAARAQLEAADKDYTCALERGASRSTFTCSAPRRGTGATRWARRRTARPPANSPRRPKWTSWSAERCASLRTRRARSRTSAAPRNSTRGPWSRSRTRPTFWPTA
>NZ_CP011271.1|WP_052559274.1|1801899_1803813_-|response-regulator
MPTSVLIVEDERIIALGIQKRLTSMGYSIAGLAATGADAVRKATDLRPSIVLMDIRLEGDMDGIEAAARVRGQLDLPVVYLTANSDPETLRRAKITEPYGYVLKPYEDRDLQTAIEMALYKHEMERRLRDNERWLAATLGSIGDGLIAIDEGGRVRFMNGLAEQLTGWAAVDAQGRPVEEVFPIVSDRTRALVTNPALEALRTRQPAAIAEGTLLLQRAGGEVPIDDSAAPISDANGRLAGAVLVFRDVTERKRLEEHLRQAQKMEAVGRLAGGIAHDFNNIMTVIGGFSELILSGILPPSEVREHLQEVKAASDRAAALTRQILAFSRKQILLPCALNLNAVVRDTAGMVRRLIGSHIEFATEADPFLGSVMADPTQITQVLMNLALNARDAMPRGGRLTVRTSDLRLDDGAVPPIPGLKPGRYAVLEMTDTGSGMTDEVKGKIFEPFFTTKGNQGTGLGLSTVYGIVSQTGGDVGVVSAPGRGTTFSVYLPVSEPLPDPRAAEGGPQTDRGSETILVTDDDAGVRRVITMLLAQKGYAVLDASSGPEALGLARAHAGPIHMLLTDVVMPGMSGGELAQAVVPLRPGIKVMFVSGYTEDALVERGLAESTAVFLHKPFTAEVLTRLVREVLDRPAV
>NZ_CP011271.1|WP_082839092.1|1803841_1807780_-|PAS-domain-S-box-protein
MESRHSRWRRWAVVPGLALVYAATARMGLALGLPPDHKVTAIWPPSGIAFAAVLIFGPRVWPGIWLGAVLANVWDAFTPVGAGAFGAHLGAAIAIASGSTLQALAGAQLVRRAAGAVPPLDRARHVFRFVALVPGACLIAATIGVTALCTSGLAPWGAFGTLWWTWWLGDAVGVLVVAPVLLTWGRPRAPGANRPGAGEAVGMFALLLGASVLAFGGWEHTGARASPLAYLSLPFLVWASVRFGPRGAALTVVVIAAFAVWGTVRGTGPFVRADVYESLLLLDVFLAVAVVTSLVLCAVLRERADIEAALRASEAQLRNLAEAIPQIVWGTTPDGAVSYLNQQWTEYTGLTGAAPDDLARVVHPDDLKRLLGAHADARRAGAVFQSEFRMRPVRGGEYRWFLVRSVAVVGPDGAPAGRIGTSTDIDELKRAQAELVRQRADLQLILDTVPALIFHKDRDHRLVRVNNELVRLVGLPREALEGRTDAEIGSPHAEQYRRDDEAIMTEAREVRGVIEPLYTLAGTRWLQTSKLPYRDATGRVTGLIGFSVDVTEQKLAQDEVRRLNAELEQRVAERTAIAEARATQLQRAVGALREQKQLLQTVLDSLGEAVLVVDKNGKFLMQNRAFRQLHPEPTEHLSPIERARVNGVYLPDGSAPCPPDRLPIFLAMRGESCDDVELMTVSNAHPDGIPISVTGRPILGPNGVEGGVIAIRNVSDARTAARALRESEKRFRAIFDQTFQFIGLMTADGTVIEANRTALAAAGLSEDEVLGKPFWETPWWTHDPVQQDRLRDAIARANRGETVRFVTTHRAANGELLWVDFSLKPFHDENGTVTLLIPEGRDITAIKRSADALEAADMLLRQFIKHAPAAIAMLDTEMRYVQASDRWLTDYHLTGQNVIGRSHYEVFPDIPERWKRIHRRVLEGAVEMCSEDPFPRDDGNIEWLQWEARPWRKAGGEIGGLVFYTQVITDRIRAAEALRESEERFRSAFDAAPIGVALVSPEGRWLKVNQSVCALVGYSEAELLTIDFQTITHPDDLGADLALVEQVLRGELASYQMEKRYFHKSGHVIDVLLAVSLVRDARGEPLYFISQIQDITERKRAEARLLASVHEKEVMLKEIHHRVKNNLQIISTLLDLQADGITDPEALAAFRESRGRVRSMALIHERLYRSENLASVEFGTYVLNLAEDLFRAYRADDEAIRLTVSVTVPPVPLDIAIPCGLLINELVSNCLKYAFAGREGGMIEVSLVRAEPGTNVLTVADDGVGLPPGFDFRQSTSFGLQLANTLVDQLGGEITLNGTGGTRFTIRFPARG
>NZ_CP011271.1|WP_052559280.1|1808076_1808574_-|hypothetical-protein
MNVIQTFPFTGAALLFSGAAGLFMLATGTDVVHLEFFAEETRPVHKFDDLGLALVLLVGAFGLDRTVAAGRLRRERELETERLRVLKATMRTVHDIVNNFLNGLQLVRIEGEGVLPAETLDLLDVLSRDTATKLKALGDLESVPEREMASGIGIDFAQNAGNRTE
>NZ_CP011271.1|WP_082839093.1|1809121_1811851_+|glucosidase
MNAEAARLEEARAGAPWRKWGPYLSERQWGTVREDYSASGNAWDYFSHDQARSRAYRRGEDGLAGISDDKQHLCFALALWNGADPIIKERLFGLTNSEGNHGEDVKEYYYYLDSTPTHSYMRYLYKYPQGAYPYSDIVDTNRRRGRTEPEYELIDTGAFANNRYFDVFVEYAKAAPEDVLVRVTVANRGTEAATLHVLPTLWFRNIWSWGAAPAPKPALHEVDGPRGLRTVVAAHEELGPRWFYCDGEPELLFTENETNNERVFGSPSASPFVKDAIDRYLVHGERAAVNPARTGTKVAAHYTITVPPGGQTVIRLRLSDTPPGSAQVPFGSAADAAFGARAREADEFYAKVLPRAATADEAAVARQALAGMLWSKQFYSFNVHNWLVERGVDPMRQRPIAQRNRDWFHMANAHVISMPDKWEYPWYAAWDLAFHCVPLAMVDSDFAKQQLDLMLSAAYLHPNGQLPAYEWNFSDVNPPVHAWAALYVYRIEQAQRGEGDRAFLARMFSKLMLNFTWWVNRKDRFGHNVFEGGFLGLDNIGVFDRSAPLPGGGYLEQADGTAWMAMFCQNMFEIGVELAAHDPEYDELTTKFVEHFLWIANALNRVGDDGMWDEEDGFYYDVLRFPDGRSERLKVRSLVGLLPLAATCVIEPQQREHVPRMLAYMAERVRVMPHLVRGAHPLGAENRGCGDRGLAALVGPERLRRILSRVLDENEFLGPYGLRSISRYHLDHPYSVTVEGQEYRVAYLPAESDSGMFGGNSNWRGPVWFPINILIVRSLLHFYLYYGDTFRVECPTGSGVEMNLFEVAREISTRLNAIFLKDASGRRPVFGAAEKFQADPHFRDHLLFYEYFHGDNGAGIGASHQTGWTGLVAKTIELFRTLDAEKLLDTGRSGAYAPAGCNGVPAPNG

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Crispr_ID: NZ_CP011271_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_6

2560494-2560584

Orphan

Consensus_repeat	Method
CCCGCAAGGGCGGCGGGTGACGCGC	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NZ_CP011271_6

>merge|NZ_CP011271|6|2560494-2560584|CRISPRCasFinder
CCCGCAAGGGCGGCGGGTGACGCGCCAACAGTACGCGGAGTACCGGTCGACCGAGGTCGGAGTGCCCCCGCAAGGGCGGCGGGTGACGCGC

>NZ_CP011271|6|6|2560494-2560584|CRISPRCasFinder
CCCGCAAGGGCGGCGGGTGACGCGC	CAACAGTACGCGGAGTACCGGTCGACCGAGGTCGGAGTGCC
CCCGCAAGGGCGGCGGGTGACGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_082839500.1\|2549191_2549779_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082839499.1\|2546437_2548042_-\|citramalate-synthase	unknown	unknown	gnl\|CDD\|237068
NZ_CP011271.1\|WP_082839504.1\|2553672_2553900_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082839513.1\|2565103_2565586_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP011271.1\|WP_082839515.1\|2565873_2566632_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240074
NZ_CP011271.1\|WP_157469407.1\|2554014_2554323_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_162271663.1\|2561913_2562141_+\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|378250
NZ_CP011271.1\|WP_082839516.1\|2566845_2567745_+\|30S-ribosomal-protein-S2	unknown	unknown	gnl\|CDD\|235396
NZ_CP011271.1\|WP_082839511.1\|2562673_2563600_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224513
NZ_CP011271.1\|WP_157470390.1\|2563624_2564059_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|235142
NZ_CP011271.1\|WP_082839509.1\|2560915_2561821_+\|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl\|CDD\|223777
NZ_CP011271.1\|WP_157469405.1\|2553173_2553491_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082839502.1\|2551953_2552937_+\|WD40-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|238121
NZ_CP011271.1\|WP_082839512.1\|2564100_2564967_+\|tRNA-pseudouridine(55)-synthase-TruB	unknown	unknown	gnl\|CDD\|211339
NZ_CP011271.1\|WP_082839501.1\|2549850_2551470_-\|L-aspartate-oxidase	unknown	unknown	gnl\|CDD\|223108
NZ_CP011271.1\|WP_082839507.1\|2554587_2555142_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082839508.1\|2555505_2560275_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|173412
NZ_CP011271.1\|WP_082839517.1\|2567880_2568738_+\|translation-elongation-factor-Ts	unknown	unknown	gnl\|CDD\|236491
NZ_CP011271.1\|WP_052559813.1\|2548381_2548945_-\|Uma2-family-endonuclease	unknown	unknown	gnl\|CDD\|368559
NZ_CP011271.1\|WP_052559803.1\|2562316_2562628_+\|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_082839499.1\|2546437_2548042_-\|citramalate-synthase	gnl\|CDD\|237068	PRK12344, PRK12344, putative alpha-isopropylmalate/homocitrate synthase family transferase; Provisional.	0
NZ_CP011271.1\|WP_082839515.1\|2565873_2566632_-\|hypothetical-protein	gnl\|CDD\|240074	cd04723, HisA_HisF, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase (HisA) and the cyclase subunit of imidazoleglycerol phosphate synthase (HisF). The ProFAR isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-ribosyl)-4-imidazolecarboxamide). In bacteria and archaea, ProFAR isomerase is encoded by the HisA gene. The Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)-formimino-5-aminoimidazole-4-carboxamide ribonucleotide (PRFAR) to imidazole glycerol phosphate (ImGP) and 5'-(5-aminoimidazole-4-carboxamide) ribonucleotide (AICAR). This conversion involves two tightly coupled reactions in distinct active sites of IGPS. The two catalytic domains can be fused, like in fungi and plants, or peformed by a heterodimer (HisH-glutaminase and HisF-cyclase), like in bacteria.	7.32841e-46
NZ_CP011271.1\|WP_082839513.1\|2565103_2565586_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.44997e-17
NZ_CP011271.1\|WP_082839511.1\|2562673_2563600_-\|hypothetical-protein	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	7.57239e-47
NZ_CP011271.1\|WP_082839516.1\|2566845_2567745_+\|30S-ribosomal-protein-S2	gnl\|CDD\|235396	PRK05299, rpsB, 30S ribosomal protein S2; Provisional.	1.89155e-129
NZ_CP011271.1\|WP_082839509.1\|2560915_2561821_+\|rhomboid-family-intramembrane-serine-protease	gnl\|CDD\|223777	COG0705, COG0705, Membrane associated serine protease [Amino acid transport and metabolism].	1.02774e-27
NZ_CP011271.1\|WP_162271663.1\|2561913_2562141_+\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|378250	pfam09723, Zn-ribbon_8, Zinc ribbon domain. This entry represents a region of about 41 amino acids found in a number of small proteins in a wide range of bacteria. The region usually begins with the initiator Met and contains two CxxC motifs separated by 17 amino acids. One protein in this entry has been noted as a putative regulatory protein, designated FmdB. Most proteins in this entry have a C-terminal region containing highly degenerate sequence.	9.18703e-11
NZ_CP011271.1\|WP_082839502.1\|2551953_2552937_+\|WD40-repeat-domain-containing-protein	gnl\|CDD\|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	1.77605e-12
NZ_CP011271.1\|WP_082839512.1\|2564100_2564967_+\|tRNA-pseudouridine(55)-synthase-TruB	gnl\|CDD\|211339	cd02573, PseudoU_synth_EcTruB, Pseudouridine synthase, Escherichia coli TruB like. This group consists of bacterial pseudouridine synthases similar to E. coli TruB and Mycobacterium tuberculosis TruB. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). E. coli TruB and M. tuberculosis TruB make psi55 in the T loop of tRNAs. Psi55 is nearly universally conserved. E. coli TruB is not inhibited by RNA containing 5-fluorouridine.	1.55658e-100
NZ_CP011271.1\|WP_082839501.1\|2549850_2551470_-\|L-aspartate-oxidase	gnl\|CDD\|223108	COG0029, NadB, Aspartate oxidase [Coenzyme metabolism].	0
NZ_CP011271.1\|WP_157470390.1\|2563624_2564059_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|235142	PRK03624, PRK03624, putative acetyltransferase; Provisional.	1.82546e-22
NZ_CP011271.1\|WP_082839508.1\|2555505_2560275_-\|hypothetical-protein	gnl\|CDD\|173412	PTZ00121, PTZ00121, MAEBL; Provisional.	1.00482e-21
NZ_CP011271.1\|WP_082839517.1\|2567880_2568738_+\|translation-elongation-factor-Ts	gnl\|CDD\|236491	PRK09377, tsf, elongation factor Ts; Provisional.	1.09778e-88
NZ_CP011271.1\|WP_052559813.1\|2548381_2548945_-\|Uma2-family-endonuclease	gnl\|CDD\|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	4.51109e-23
NZ_CP011271.1\|WP_052559803.1\|2562316_2562628_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	2.97881e-16

>NZ_CP011271.1|WP_082839508.1|2555505_2560275_-|hypothetical-protein
MAAVLEQAEAATKNGTRVDEQIAQATSRIRTHDITFGGLVLVAFVLVYATAMILLDKYLGLAEWLRQVAFLGFLAACAGIAYATILSPLRKKINPLYAAKRVESTIDDAKNSVTGYVDAQQQGTLNATVKAALAHRAAKSVAAADVNKAVDHRGLLYLGGTSVALFLTLIVLFFVFRPAQFSSLVGRTFVPFGSGDIVTRTHIDVVRPDPAEATITTGQTIVVAVHVGGKIPSTDGPDRVRLMIRHNQADPNYTELPMVQGDTSRDFELRVPDHLVQYGFWYKVAGGDYTTREYKVTVRTLPLFTEFQTTYEYPAYLRRKTENATDPQLRAPRGTTVTLVGRTNRDVREGAMVVEPGGVRVIGTPVADKPDSLAFKLKLTESGSYKLSFNATTGEHSTDSFQSRILVEADKAPEIAINKPEEDESTAPTNGQIAIDGKVGDDFGIDTITLKMKIVSPVERPLLDRPYLNGKEKSFHRKKDNTWPTDVDYKGSVDLAQLKTDPTNLPLTLTPDMVIEFWLEATDNCTEPKPNVGRSVAKRVRLTPPKVEPQDKQKLDQDKANRKDEEQKHDAQQEQKLDQENRDPKNGNNGGQNQNQPDQKTEPKNGTNGEGTKEAPPDPTKMPPPNKDKGEQKSDTPMGGMSETGNPMGSPMPKGGMNDPSPKPMGSPEPNGTNTQNGTRPDNPMPEAPPPKSPDEKSVQDRADKLNNAIEKEKQEGGSGKSNPSANENERTDSAQQKKQPPAGDMGNATEPKPEPKQGETKSPMQDNAPASGKSEGKLEQPSNPAEPKPEPKQGETKPGNDPMNKPGQKNTAPSETRDEPVGAPPGVDKEPKQSQPNPKDPNPKDPNPNPDQKQDPNSGSRGKSASQKDDGQQGGMSDSSDKKDPAADAGSGPKPMREPTRGEDKPNQPKNQPQPAGGAKSENKQPDAGDAKPNKAPAPSENKPKPEDMTSGGMGTPESKPEGGANQSTKPNGTGAAETKPAGNKNAPMNAGNSGADEGRDKPPPQEGAQPSGGRDQEPPKQKELDDNQRKELEEAARNLTSPDEKKKQDARNKLDKAIGEDKRKEMEKLANDLQSPDENKRADAQRKLEELKKQAQQQQGKQNGENGGKPDEKQMKELEQAAKDLNSPDKNKQQEARDKLDKAIGEDKRKELEQLAKDLQSGDKDKQQAAQKKIEDAMKNAKGGGGDQGDQKNAPKLDEKQMKELEQAAKDLTSPDEKKKQDARNKLDKAIGEDKRKEMEKLANDLQSPDENKRADAQRKLDELKKQAQQQQGKQNGENGAKPDEKQMKEIADAMKDLQSGDEQKKQAAQQKLDKMVGEKNRKEAEQLMKDLQSNNKETREAAEKKLDDLKKQLEKQQAGKNGKDGKGKEPSKEELADLMKKAQDLQSKDKDTREKAEKDLDDKLGKENREKLQKELEDKKPGGDPQQDEKLKEELERMAKEQSNPSHDPTTQTGPGSSPKPKGAMEEDPQNRLKTAELRLEDFEKKRYDEEFQKKQGFTQAEYEKFLDNYTKHVENLRKEANQPAGNKPPQPGSSEPGAPILGGTGSKVAPAAKLDSSGTGGGSTVAPPGFEDSKKKFQKLIQEKK
>NZ_CP011271.1|WP_082839507.1|2554587_2555142_-|hypothetical-protein
MNGDQHNPRLQWAVFVVLAVIDAGLLVKLFVGSSDIVGLLIGIGIVSALLVVTVRIFDLGSLSVGKEGMKAELREVKDEVGVIQNRQDEQERYLDAFFRILSERLTLPMKYHLRALARGGEMYKGQDSLRQDLLQLKRFGLIEEVSPQKIGDFLDGKDANVASFVRLTQTGEKFLLALDKIEAQ
>NZ_CP011271.1|WP_157469407.1|2554014_2554323_-|hypothetical-protein
MTVALPPGRTVAEVVEVVIQAALSGIGDAETERRLSAEFGLSADDAALARDRAFGGLVRAGTRIPENCPSPVKDPVAWESFQRGTRDPALVSRIYPQMFPGS
>NZ_CP011271.1|WP_082839504.1|2553672_2553900_-|hypothetical-protein
MHTLTVRTRFTFGDRVRFESQLQRCSGIGTVAGIMVSSDGSVDYMIEIARADGYSDFQPGILEGELALLSPAEGM
>NZ_CP011271.1|WP_157469405.1|2553173_2553491_-|hypothetical-protein
MRKLSRTARRYWQPVCCLAVVNFAVFFVVSTQIGGDAVSGRIEGGRYVLSNHGVRTEVSRTVYNYSLIHTVSVWVTHGLAVGGGLILQALGRLYESQPPSGTVGK
>NZ_CP011271.1|WP_082839502.1|2551953_2552937_+|WD40-repeat-domain-containing-protein
MRFLTSRMRVVDQVAFARDGRRLFAAGSNVPDLRYKPDNRGIDVWDLAGGPNPVSHLFPDQLIAGFAVNPAGRWLYVGTGYDYPDEHTSRYFAVDLTSEGIISLGLRGGNSFILGTHPSGEWFVGYGYKTNWQTRRLVRWRQSSAGVPTEEWEIAPSASRFYTSQIACAPTEELLVTHDIESGIAVRDQVYELVTRDPGTGVVRGKIPIPGRIVDQLLFSPDGAYLVVRGGPSLLVWDARDLTRKPQKIRGAGKGHFTGLAFDPTGRYLAAASNDRSVNVYETATWGLARSFSWDIGRMRSVAFSPDGLLMAAGSDVGQIVLWDIDL
>NZ_CP011271.1|WP_082839501.1|2549850_2551470_-|L-aspartate-oxidase
MSAANRYLVSFDARDTFHRFADVLIIGAGIAGLRAALEVPSDLSVLVVTKDRVTESNSSYAQGGIAGVRSPEDTFENHVEDTLVAGDGLCDREVVELVVREAPHQIEKLIEFGTKFDEENGQLALTREGGHSHRRIVHALGDSTGFEMMRATIAYARTRPNIRIWDDTFTIDLLTHEGACCGAAVARNGMGKFLIWAKQVILASGGCGMVYRETTNPPVATGDGMAAAYRAGAELRDMEFMQFHPTVLYVAGSARYLISEAVRGEGAYLRDVNGERFMPASDPRAELAPRDVVARAIFRTMEKTQHPNVYLDLAHLDPAMVLNRFPGINRVCKSFGLDITKDRIPVRPGAHYMVGGVSVDQHGRTTVPGLWAAGEVTSSGLHGANRLASNSLIEGLVYGTLCGRGAADAIRKMPRDMTAYPIRSIIPPAEEGTGLDTADLVASLRALMVRKMGIVRERTRLLEAKEDLRFWCRYALSREFDGKAGWELQNLLTIARLMIASALTRDESRGTHFRSDFPARDDQRWGLRHVACEPFVALS
>NZ_CP011271.1|WP_082839500.1|2549191_2549779_-|hypothetical-protein
MKVLVLAVAVLLVLTAAVSAEDKKPAGPITLTLVAKTDKYKFDGGGKTADEYKKELEAIAKKQADGEAVRSPKPPAVDLVLKITNTSKEEVTIYVGGDSNVFTFDLTGGPGTVAMNSGLAFTADFRLPNAVTLAAGKSHEIPVKQLSDGSRGSSRFVYWTGPGEYKLSAKYQLSDKDGGKGTELTSEPVKITVEK
>NZ_CP011271.1|WP_052559813.1|2548381_2548945_-|Uma2-family-endonuclease
MSTVVSPRATLDDLMQVDGKAELINGRIVRIMPSGFLPGRVARRITRSLEDFVASGGHGEPIADNVGYAFDPPLPSGRQTLSPDSSFYTGPLPTNLMRFIDGCPVFAVEVRSEHDYGPKPDLEYAEKRADYFAAGTLVVWDVDPVAETVTVYTTTAPTTPTVFHRGDTADAEPAVTGWCLSVDAIFA
>NZ_CP011271.1|WP_082839499.1|2546437_2548042_-|citramalate-synthase
MRVSIYDTTLRDGSQGEGVNFSLQDKLLLTRRLDEIGVDYIEGGYPLSNPKDFEYFQAVREIPLKHAKVCAFGMTRRKNAPAETDTCLKALLDAKTPVVTIVGKTWDFHVTEVLGTSLDENLRMIADSVAFCKSQGREVFYDAEHFFDGYRANPEYALKTLQAAATAGASVVILCDTNGGTMPERIAEVVGAAKRAVPCEVGIHCHNDCELAVANSLAAVRAGATQVQGTMNGIGERCGNVDLLSVIANLALKYKYDVLTPGSLARLTETSRYVYELANLNHRVGQPFVGASAFAHKGGMHTHAVAKDPTTYEHITPEAVGNERRILVSELSGQSTILTKTAKYELNHDKALMAKILNAVQNLENQGYEFEAAEASFDLLVRKVAKEHKPWEVDKKLKLYQPWFERVTYRVNIEARENNTPITEATVRLKIAGQIEHTASEGDGPVNALDGALRKALVRFYPRLNEMQLVDYKVRVVNPRAGTAARVRVVIESRDGTDVWGTVGVSENVIEASWLALCDAIEYKLFKDEERPKR
>NZ_CP011271.1|WP_082839509.1|2560915_2561821_+|rhomboid-family-intramembrane-serine-protease
MGIQDRDYYREGPSFLDRVGQQGATVWLIAITVGVFFGQIMTGWPRALSPLVAYGAFDTDAVLRGEVWRLLTGAFLHADLWHLFFNMLILYWAGTSLEAVRGSRELVLFYLFSAVGANVFYLGGQLVGLTAVGKAIGASGAVTATLVLFAFHFPRAQVRLYFFIPMPVWLMVVVFVGFDALFALGAADPRGGRIAYLAHLGGAAFGLIYFQSGVRFSNLFTAAPKTRARPKLRVIAPPVEDAPAPVAAVVEAPPRRPADEQLEAKLDAVLEKVSKYGPESLSPDEREIFYRAGELYKKRRK
>NZ_CP011271.1|WP_162271663.1|2561913_2562141_+|zinc-ribbon-domain-containing-protein
MPLYEYTCRKCAHAFETLVSSRVAIAVTCPKCESPDLDQLIGLPAPGRVTEGGAATNCRGDGPPCGAPWCGRKGP
>NZ_CP011271.1|WP_052559803.1|2562316_2562628_+|winged-helix-turn-helix-transcriptional-regulator
MTEKKQAEECATMLQALAEPNRIRIIECLRTGSMNVTQLAKALDVEIVNVSHHLGVLRLAGLVEDIKDGRFVIYSLHPKVFRSDNTKGTYLDLGWCRVEIPHN
>NZ_CP011271.1|WP_082839511.1|2562673_2563600_-|hypothetical-protein
MHATCVIYNPAAGRGRAERLLKALPPALAAGVELRPTSRATHAIELAREAANEGFAKVVAAGGDGTVHEVANGILQSDQRDTIFSVWPIGSANDFAFTLGMDRWWAQRERNAPTETLEIDVGRVTTANRVVHFVCNLGVGFNGMVNGEARRTRWLKGLPLYAWAFLKALVKHFDRPTMTIRFDERVVTTPTLALSVLNGQREGNFPLRPRASLTDGLFDYMHATRLTRMHLLRYLPAMARGKLPENHRLVGLGRAGRIEVSCEIPLCVHADGEFVCVPDEGIKEISLEALPKRLRVEVFPPALYGGLK
>NZ_CP011271.1|WP_157470390.1|2563624_2564059_+|GNAT-family-N-acetyltransferase
MALRPMTEEDIPAALALWQGLAGIGLRDADNPAALAKYLRRNPGCSFVALDKAGTLIGVSLAGHDGRRGYLHHVAVSESHRKQGLGRELVDRCAAALKAEGIEKINFWVKADNAAGLAFWNRIGGRERTDLVIVSLILGDNPNA
>NZ_CP011271.1|WP_082839512.1|2564100_2564967_+|tRNA-pseudouridine(55)-synthase-TruB
MNGLLVIDKPGGITSRDAVNRVQRWFPRKTKIGHTGTLDPLATGVLVVCIGAATRLADYVQAMGKSYSSRFRFGATSTTDDADGEVTETPNAPVPTREQIDAALAAFVGNVEQVPPAVSALKLDGVRAHELVRRGLGPKLNARVVSIYAIRVTGFAWPYLDVEVDCGKGTYIRSIARDLGDVLGCGGLVQTLRRTRVGPFRVEQGMSLDADPASAKLLPMAEAVAGMKHVSLNADDVTRLRHGQRIRLPENNALPEGEELAVLDGQTGLVGIGIVERGQLKPQLVFGV
>NZ_CP011271.1|WP_082839513.1|2565103_2565586_+|GNAT-family-N-acetyltransferase
MIRSATPGDVPVIANLIRALAEYEKLAHAVVLQEADLHRHLFGATKFAEVLLVEDAGAVVGFALFFHNYSTFRAKPGIYLEDLFVIPEARGKGHGKALLRALAKLAVERDCARVEWSVLNWNEPSIQFYKSLGAKPMDEWTVYRLTDDALTKLAASGDGR
>NZ_CP011271.1|WP_082839515.1|2565873_2566632_-|hypothetical-protein
MLAQRARPRLIPVLDVMNGHVVRARGGVRENYRPIACPFSGSREPTDVAQAVLKLANANELYIADLDAITEKRSVSRATQNILNQCPVPTWLDAGIGRTDVLDFPETPHLRPVVGFETCHKPEILLETLIEPLRRPVAFSLDLKGGRLLGNWRAWGLDGDRDVMPLARRVIEMGVRALIVLDLARVGTGTGTGTEPLLRAIRNEFPDIDLIAGGGVRTWADVDALGEVGATGVLVASALYDGTLSGHNQSGE
>NZ_CP011271.1|WP_082839516.1|2566845_2567745_+|30S-ribosomal-protein-S2
MALVDVKVLLEAGVHYGHRASRWNPKMRPYIYGKRNLIHIIDLRETVRGLLRAYRYLNQVVARGGLVMFVGTKRQAKEIVEKEASRCGMPFVSERWLGGTLTNYRTIRNRLKRLQELEAMWLPQGENPNRVDLNAHIASLMTDAGKLDPALAPDTADILTHSKKMISTLSRELLKIRRNLMGIRDMIKPPDALVIVGPNKEHIAVKEAKRMGVTTIALIDTDSDPDPVDLPIPGNDDSIRSIEVILAKLADACLEGRAALPPEQQGIQKTRVQQPKPPAPPAPPAPPAPESNPAPAGAV
>NZ_CP011271.1|WP_082839517.1|2567880_2568738_+|translation-elongation-factor-Ts
MPAVTPLMVKQLRDRTDQPMGLCKQALDESAGDMDAAIVWLQKQNSKMTAKREGNETAEGRIGVSVDNAAKVAAIVEMRCESAPSAKSDQFIALANDLAKAAAGSKGADAPALLVEPFGGKGTVQDRINDVVGVIREKMVLHRFQRLEGGVYGGYVHHDGTVGVLLECKGAAANDELLRDVAAHIAALNPPYAITTDVPSDVVEKEKGLVKADMDADPKNTGKPANILEKIAEGKLRTRLSEIVLSEQPMANAGKYPNTSVGAALKKAGLEPVRFVRFKVGAVAL

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Crispr_ID: NZ_CP011271_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_7

2703388-2703482

Orphan

Consensus_repeat	Method
ACCGAACCGGCGGAACAACCGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_7

>merge|NZ_CP011271|7|2703388-2703482|CRISPRCasFinder
ACCGAACCGGCGGAACAACCGGCGCCCGCGCTTGGCGCAAGGCGGACGGCACCAGTACCGACGCCCCGGGTGACCGAACCGGCGGAACAGCCGGC

>NZ_CP011271|7|7|2703388-2703482|CRISPRCasFinder
ACCGAACCGGCGGAACAACCGGC	GCCCGCGCTTGGCGCAAGGCGGACGGCACCAGTACCGACGCCCCGGGTG
ACCGAACCGGCGGAACAGCCGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_052561310.1\|2709933_2710755_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237512
NZ_CP011271.1\|WP_052561336.1\|2701252_2701753_+\|flagellar-basal-body-associated-FliL-family-protein	unknown	unknown	gnl\|CDD\|377123
NZ_CP011271.1\|WP_052561318.1\|2707152_2707461_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082839577.1\|2705430_2707137_-\|flagellar-hook-length-control-protein-FliK	unknown	unknown	gnl\|CDD\|350657
NZ_CP011271.1\|WP_052561320.1\|2705032_2705389_-\|flagellar-hook-capping-protein	unknown	unknown	gnl\|CDD\|235847
NZ_CP011271.1\|WP_052561343.1\|2699137_2699347_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_162271671.1\|2695820_2696306_+\|flagellar-protein-FlgN	unknown	unknown	gnl\|CDD\|377465
NZ_CP011271.1\|WP_052561345.1\|2698034_2698976_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274195
NZ_CP011271.1\|WP_082839573.1\|2699401_2700262_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|130902
NZ_CP011271.1\|WP_052561312.1\|2708872_2709718_-\|flagellar-motor-stator-protein-MotA	unknown	unknown	gnl\|CDD\|274801
NZ_CP011271.1\|WP_052561338.1\|2700258_2701077_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371669
NZ_CP011271.1\|WP_052561316.1\|2707543_2708167_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082839576.1\|2703690_2704947_-\|flagellar-hook-protein-FlgE	unknown	unknown	gnl\|CDD\|235557
NZ_CP011271.1\|WP_082839578.1\|2708255_2708822_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236365
NZ_CP011271.1\|WP_082839579.1\|2710846_2712232_-\|CRTAC1-family-protein	unknown	unknown	gnl\|CDD\|369440
NZ_CP011271.1\|WP_082839574.1\|2701749_2702601_+\|flagellar-motor-switch-protein-FliM	unknown	unknown	gnl\|CDD\|376445
NZ_CP011271.1\|WP_052561327.1\|2702626_2702989_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376445
NZ_CP011271.1\|WP_082839580.1\|2713004_2716691_+\|prolyl-oligopeptidase-family-serine-peptidase	unknown	unknown	gnl\|CDD\|366374
NZ_CP011271.1\|WP_162271670.1\|2695495_2695876_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274188
NZ_CP011271.1\|WP_082839572.1\|2696331_2698023_+\|flagellar-hook-associated-protein-FlgK	unknown	unknown	gnl\|CDD\|224176

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_052561310.1\|2709933_2710755_+\|hypothetical-protein	gnl\|CDD\|237512	PRK13800, PRK13800, fumarate reductase/succinate dehydrogenase flavoprotein subunit.	2.08435e-06
NZ_CP011271.1\|WP_052561336.1\|2701252_2701753_+\|flagellar-basal-body-associated-FliL-family-protein	gnl\|CDD\|377123	pfam03748, FliL, Flagellar basal body-associated protein FliL. This FliL protein controls the rotational direction of the flagella during chemotaxis. FliL is a cytoplasmic membrane protein associated with the basal body.	4.65732e-18
NZ_CP011271.1\|WP_082839577.1\|2705430_2707137_-\|flagellar-hook-length-control-protein-FliK	gnl\|CDD\|350657	cd17470, T3SS_Flik_C, C-terminal domain of flagellar hook-length control protein FliK and similar domains. The flagellar hook-length control protein FliK is a soluble cytoplasmic protein that is secreted during flagellar formation. It controls hook elongation by two successive events: by determining hook length and by stopping the supply of hook protein. It contains an N-terminal domain that determines hook length and a C-terminal domain that is responsible for switching secretion from the hook protein to that of the filament protein, by interacting with FlhB, the switchable secretion gate.	2.68857e-21
NZ_CP011271.1\|WP_052561320.1\|2705032_2705389_-\|flagellar-hook-capping-protein	gnl\|CDD\|235847	PRK06655, flgD, flagellar hook assembly protein FlgD.	1.55422e-21
NZ_CP011271.1\|WP_082839572.1\|2696331_2698023_+\|flagellar-hook-associated-protein-FlgK	gnl\|CDD\|224176	COG1256, FlgK, Flagellar hook-associated protein [Cell motility and secretion].	4.52404e-65
NZ_CP011271.1\|WP_162271671.1\|2695820_2696306_+\|flagellar-protein-FlgN	gnl\|CDD\|377465	pfam05130, FlgN, FlgN protein. This family includes the FlgN protein and export chaperone involved in flagellar synthesis.	0.000120252
NZ_CP011271.1\|WP_052561345.1\|2698034_2698976_+\|hypothetical-protein	gnl\|CDD\|274195	TIGR02550, Flagellar_hook-associated_protein_3, flagellar hook-associated protein 3. This protein family consists of flagellar hook-associated proteins designated FlgL (or HAP3) encoded in bacterial flagellar operons. A N-terminal region of about 150 residues and a C-terminal region of about 85 residues are conserved. Members show considerable length heterogeneity between these two well-conserved terminal regions; the seed alignment 486 columns, 393 of which are represented in the model, while members of this family are from 287 to over 500 residues in length. This model distinguishes FlgL from the flagellin gene product FliC. [Cellular processes, Chemotaxis and motility].	6.15314e-41
NZ_CP011271.1\|WP_082839573.1\|2699401_2700262_+\|hypothetical-protein	gnl\|CDD\|130902	TIGR01843, Hemolysin_secretion_protein_D_plasmid, type I secretion membrane fusion protein, HlyD family. Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking].	4.50809e-05
NZ_CP011271.1\|WP_052561312.1\|2708872_2709718_-\|flagellar-motor-stator-protein-MotA	gnl\|CDD\|274801	TIGR03818, MotA1, flagellar motor stator protein MotA. The MotA protein, along with its partner MotB, comprise the stator complex of the bacterial flagellar motor. MotAB span the cytoplasmic membrane and undergo conformational changes powered by the translocation of protons. These conformational changes in turn are communicated to the rotor assembly, producing torque. This model represents one family of MotA proteins which are often not identified by the "transporter, MotA/TolQ/ExbB proton channel family" model, pfam01618.	1.27863e-123
NZ_CP011271.1\|WP_052561338.1\|2700258_2701077_+\|hypothetical-protein	gnl\|CDD\|371669	pfam11684, DUF3280, Protein of unknown function (DUF2380). This family of proteins with unknown function appears to be restricted to Proteobacteria.	0.00695172
NZ_CP011271.1\|WP_082839576.1\|2703690_2704947_-\|flagellar-hook-protein-FlgE	gnl\|CDD\|235557	PRK05682, flgE, flagellar hook protein FlgE; Validated.	6.66665e-100
NZ_CP011271.1\|WP_082839579.1\|2710846_2712232_-\|CRTAC1-family-protein	gnl\|CDD\|369440	pfam07593, UnbV_ASPIC, ASPIC and UnbV. This conserved sequence is found associated with pfam00515 in several paralogous proteins in Rhodopirellula baltica. It is also found associated with pfam01839 in several eukaryotic integrin-like proteins (e.g. human ASPIC) and in several other bacterial proteins.	5.09734e-20
NZ_CP011271.1\|WP_082839574.1\|2701749_2702601_+\|flagellar-motor-switch-protein-FliM	gnl\|CDD\|376445	pfam01052, FliMN_C, Type III flagellar switch regulator (C-ring) FliN C-term. This family includes the C-terminal region of flagellar motor switch proteins FliN and FliM. It is associated with family FliM, pfam02154 and family FliN_N pfam16973.	3.57916e-14
NZ_CP011271.1\|WP_052561327.1\|2702626_2702989_+\|hypothetical-protein	gnl\|CDD\|376445	pfam01052, FliMN_C, Type III flagellar switch regulator (C-ring) FliN C-term. This family includes the C-terminal region of flagellar motor switch proteins FliN and FliM. It is associated with family FliM, pfam02154 and family FliN_N pfam16973.	3.66082e-22
NZ_CP011271.1\|WP_082839580.1\|2713004_2716691_+\|prolyl-oligopeptidase-family-serine-peptidase	gnl\|CDD\|366374	pfam00930, DPPIV_N, Dipeptidyl peptidase IV (DPP IV) N-terminal region. This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.	4.35161e-83
NZ_CP011271.1\|WP_162271670.1\|2695495_2695876_+\|hypothetical-protein	gnl\|CDD\|274188	TIGR02541, Peptidoglycan_hydrolase_FlgJ, flagellar rod assembly protein/muramidase FlgJ. The N-terminal region of this protein acts directly in flagellar rod assembly. The C-terminal region is a flagellum-specific muramidase (peptidoglycan hydrolase) required for formation of the outer membrane L ring.	3.97331e-11
NZ_CP011271.1\|WP_082839578.1\|2708255_2708822_-\|hypothetical-protein	gnl\|CDD\|236365	PRK09041, motB, motility protein MotB.	6.4868e-18

>NZ_CP011271.1|WP_052561327.1|2702626_2702989_+|hypothetical-protein
MAEPTTTTDPTDADPAVVAKHPQFPELDPAAASGSGATLDSLRDVPITITARLGHTVLPIAEILTLGPGSVVELDELINAPIELTVRGVPFAVGEVVVVNEHFAVRIKNLLPPRIGRTDL
>NZ_CP011271.1|WP_082839574.1|2701749_2702601_+|flagellar-motor-switch-protein-FliM
MTPAEFDFRKPPLGQIERNVSAWLTSACRWATEAAASTLPYPATFQFAGLETPTATASIHALPEGAVGIVLATPDIIGTGAALLALPNPLFLALLSGLVGEAPAELPAGREATPLELSLVPHLVRELFINPLTKSWPARVPPALDVSAPSIPSAVWRAGNERVMVATLTITGPFGAQPVYLMLARTGPWEDLGAAPVEQVAPVPREVIETLVREMNVEMTVVLGKADLTMHDVTSLVPGDVVVFDQKVTQPLEGLVSGTRKFRVWPGVVGDRAAVVVDTITGD
>NZ_CP011271.1|WP_052561336.1|2701252_2701753_+|flagellar-basal-body-associated-FliL-family-protein
MSTPAAGAPRKKSRKLLLIVVCLVAIAGGAVVPMAMGGALPFGKAADKDKEKSKAKGKDNKTAIVPFGEVTVNLAEERQQRYLRTKIAILVDAEAEKEMTELVTKKKAAVKSTLIGHLAGKNTKDVSGSVGVQRMQRELLERIEEVLYPDGNSRIRAVLFEEYVVQ
>NZ_CP011271.1|WP_052561338.1|2700258_2701077_+|hypothetical-protein
MKKRLMGAAAVLTAALAGGCGLLEKVKQRDRVPPAPPTFSQYHLDGWQWENVRRVAVLPFRNESGYTRAGEEARDAFAAELQRAGRFEVISTPPDDRAILAAQVRCGGRFDEVLLYDIAMATNADVVIHGTVSNYSPYPRPRLGLVIQAVGSQEGKVVASVDGLWDSTDLAIAERVRVTYRERARERPPWIRNHVIASDDSFAADIALDSPNLFRRFVGREAVLTLLGLPVPGVVMGGGAGMGPGTAGNCQVGCAPGLAPGAPVVPAAGTMK
>NZ_CP011271.1|WP_082839573.1|2699401_2700262_+|hypothetical-protein
MNRRYIILSGLFALAAVAAGCTPLRGSRPDATVVPPPYGKSAFGSSDKPGSGGVIQAGATEPGEPVVGANKFELTGGQPVGYQSSPPGQPLAQPRPTALPPANLPPVPGATGHGTGTGTGSAPPVTAPGAPGNPAAPGAPGNPVTPGTGVPGGPGVPGAPNPNVLPAPTVYGKTWNLGPNEVPTDRVVELTRQLELVFAQNRELVARIKELENQGLKREQALVEAMREVEAAQAEVDKARGIISTQKSDITALQEKIRQLEREDIEMLKLMIGALEKLLPPARREP
>NZ_CP011271.1|WP_052561343.1|2699137_2699347_+|hypothetical-protein
MDEGRAGAGSPVVRATRVRVSEEAVRIGAPAPGGAPGEPTVRVIREGDVVQAIEVVCSCGERIRIRCEY
>NZ_CP011271.1|WP_052561345.1|2698034_2698976_+|hypothetical-protein
MNLRVTAQTRTGDAIANMRARSADLAKYQDQVSSGVRIKRASDDPTAYPQLARAKSASARLESYSQSISNATTTLNAGVSALQDVTSALTTARQIAIEGASADTAGEPANREALATQVDGLINRVLATVNARPDGQSLFSGTATNTAAFSIATTDSAGRPATIAYDGSDQRARTVTARNTTTDTRYVGSAVFQQSGADTFASLIALRDELRNNPSTGPDYSAAMNQRLADLDAARTAIGETTGEQASNLATLESQDLVVSNAKLDSDSRVNDLIGTDYPMAIVKMQEQQTALQAIYAVTAQLADPGLLAFIGR
>NZ_CP011271.1|WP_082839572.1|2696331_2698023_+|flagellar-hook-associated-protein-FlgK
MNSLQIGTSAIQTAQKALQLIGQNIANATTPGYHRQSVNLINTVTGSAGTGVDIASITRYTAAPVRTAIISGNANASYYTAQLDSRRQIETTLASGEGGVGDRLDSLFNQIEQLTSQPDSLASRRAILTAAGSVAQQLNSTAGDIDRLRSDINKQITSTVTEINDYATKIADLNNRILVTENRGNPTNDLRDQRDQLIDALSQRVDVKTVEQPSGEINVIASGAAIVVGQYANQFQAANDATGNVVITQTGVAQPVTFKSGTLGALVQDHNTTIPAIRGRLDALAGSLIQQVNQVQATGLGSSGPLASTSSTNAVSSPAALLNAAGLPFSVQAGTLTVSVTNGNVNPSTRTNTAITIDPATQSLNDIATALSAVPGLQATVNTTTNTLDIQGQAGFTFDFAGRDSVPAGSGAVANSDTSNILSALGVNGLFVGSTAVGIAVNPAVSSNPGLLAAGRTGQPGDGTNLERLGAIRDQAVFGTRTLTEEFADIASTLGTDINNISDQQTAQASTLQNLSNQELSVTGVDTNEELLHLLDYQRQIQGASKYLSVVNTAMDELMNILP
>NZ_CP011271.1|WP_162271671.1|2695820_2696306_+|flagellar-protein-FlgN
MPQPLSTITETFLQHLRVEEQFLAEVLAKANDVYAALRAGDMRAANAVTTQLNADAAGLRAASAQRATVAADLARALGLPAQDLKLSLIVETLPDPLRADVAVVRDRLTAATAELTAVQTRNANLLGHLRSFFRDVLADLTADDTPARYGPSGNWLVPSAG
>NZ_CP011271.1|WP_162271670.1|2695495_2695876_+|hypothetical-protein
MTTISDPYAAKSGATVQSKADSRLKNMAGEMEATFLSMLLKEMRQTLDPEEGGGMFPGDSGDVQGGLFDLYLGRHLADGGGIGLATALVRQMQNAAAVPKTVTPTDAHSAPTAFDHHRDVPPAPAG
>NZ_CP011271.1|WP_082839576.1|2703690_2704947_-|flagellar-hook-protein-FlgE
MSLNALFIGSSGLTTNSAALDVIGNNLANLNTTGFKSQRMLFKDVVYQTINSGSTASTNVGGTNPTQFGFGVGTGSIGTMFAQGNLNPTGRNLDAGIQGNGFFVLKSTDSVAYSRAGGFDVDAAGFLVDPSTGFRVQRFGAVGEGTATTPAFQTPGNLDIQVPFGTGVAGVATTEVSYQGNLSTSMQVNDVATTAIQVYDSQSTPRALTVTFTKTAANTFTATATVSGGTATVTGGPITFNTAGQLVSPATLTVALTGINGAAATQNITLDLGTPLASDGLSQFGGATTASAVNQDGAGFGTLTDVSIGSDGVLSGKFSNGRTLSLAQLAIAGFNNEGGLIRTGSNYFQSSVSSGEALVGVAGQGGRGSTVGGALEASNVDIANEFAKLIIAQRGFEVNAKTVSTTSDTLQSLVAILR
>NZ_CP011271.1|WP_052561320.1|2705032_2705389_-|flagellar-hook-capping-protein
MATNLAGIGQDQFLQLLIAQLKNQDPLSPVDNSQFITQLAQLNTVQGLQDLNASFSQQLKLQQLTQGADLIGKTVEYLPNGATDFKTGKVTSVEAQNGSFVLQVGSDSVTLDQIQSVR
>NZ_CP011271.1|WP_082839577.1|2705430_2707137_-|flagellar-hook-length-control-protein-FliK
MASTVASVATTFPLLQSSATTTTTTTRQTTSRTDSSDPFQTVLSQATNDARAAQAASDAAQAAVDTRAANDAAARELANQQAADQDAADQDAADAAAAQLAATLAAANQLAPINTTPDTATTGTTGAGPGQVPAGALGGTTGELAPPNVPTQNNPLFRQFVSEAAAQNNTSAPAPVTQDTNTKLNANTAATALTTPAVPQTTATTTTTAAEITTQAQTPAATNLASTIASVQPAQKQIVVPQTPIVTGLQPNQPTTGAAQLPTPVVAPQAPVEATALPDVQVGSRPTTAGEQFAQIASAAATITQNKAPAATGTETSPFATLLASTTVPTAAAPAPTTTAPATVSAPATTNALATNALTATALTSPTEINAASVNRAPTQLAEIGELTRKESNFGDATGASSATAAGTFAQALTTQASTVQQPTATVQAPTPTAQVADGIITHAHVIARGGKTEFQIRLDPPELGAVRIRLTSDGDGINGQVVVASDSVRRMIESQLPELRQRLEATGVTVQNLNIATDSGTGAGSDAGSRAFRSETPADTARQTPVATGVRPRPPTVRAPGALDVMA
>NZ_CP011271.1|WP_052561318.1|2707152_2707461_-|hypothetical-protein
MTATELVAEIRDRFKVGDAALELTGRLVSLVATIELDVARAGTLPPDLGADITRLLAQVQDTTKVGGRWLDAVADGPELANLHMRMRVQKMYGLLVREDSSP
>NZ_CP011271.1|WP_052561316.1|2707543_2708167_-|hypothetical-protein
MRLMYRVLALGAFLVPCVAAGVTAQPPSSATEKLKSDTSALAGERTAAESTTTERAKLQADLRRLIDRLEKNPPGPGVVSPTSPPISPPKTKDKDTNPGAGGAAVDKLRAAMNLVLNNEIDAALNAFRQIDLQSLSAEDRSFARFMTASCLRRQGRVAEALPIYREVGDSGEDAFIASSAVSQVALIRTGEELQAQLTQLRARPKSR
>NZ_CP011271.1|WP_082839578.1|2708255_2708822_-|hypothetical-protein
MERIVAKGGGGSWKVAYADFVTAMMAFFLVMWIGAQDVKVRQSVANYFVDPSGVSKRPTNAGAVLDAPVSGPVPENAKVEGGRGARAPGGDTPSPSTAAVLNWIKSNDKQFQRWKTEAQRCREAAAVQKAVNQTQTPEEVASNQLTSLLSTEVAGGIPKDTPDVYKDLLFGSFKEVNWKQVAEVLLTE
>NZ_CP011271.1|WP_052561312.1|2708872_2709718_-|flagellar-motor-stator-protein-MotA
MVVIVGAVIVLVSVLVGFSMAGGKVAALIHLSEFVTIGGASFGALILMSPVKVIKDLVRGVLQTIKGSSFGKAACVDLLKLQYALARLVRQEGLLALDTHVTNPDSSALLREYPRVNGNHHAREFLCDSLALILDGTVESAQLSEWLEEEISVIEREHHAASDALAKSADALPGFGIVAAVLGIVVTMQSIGGPVDEIGYKVGAALVGTFLGILAAYGFVAPLAARMQSLGDQEILFFRSMAVGVIAMNDGASPKDVVARARRVMSTDCRPNQAELKDMFG
>NZ_CP011271.1|WP_052561310.1|2709933_2710755_+|hypothetical-protein
MRCGLVLVALLTLPLAARADEADDAFAKKLGAIVRDPRQSLWARVEAANMIGKIGPNAGAATGDLIVVLDRLRPTEQEPLQEAIVEALGQLGAPAKAALPAFTRLAGRTIDLDLALKQSRDAILNSSDSQEIDALARQLLSRDPSSRLRATKALADLGPVARNAAPFLAIALGDADADVRRGAINAINRVTPNAKPTEAFVRAIALDLRDPDANYRLLAVRALGRLGAPASIAVADIDALRADPDPDVRRAVVDALNRIPIPQLPPGVTTTNP
>NZ_CP011271.1|WP_082839579.1|2710846_2712232_-|CRTAC1-family-protein
MFEDASDLIADNPPGLHYGVAVADLDRGRYSFVVAGFGGPNRVFTWSNGALRDVAPPELADAERRAVGVAAGDVDGDGREELYVLNADTFSGPKQFADRLFRRRPDGGWEDLFERPVNRGVRNLSAGRSVAVIDRRGVGRYGFFVANHGRPMRLYELAPGGALADLAPPLELARAGGGRGVLTLPVFSGHPDIFCANERGQNFAYRNRGDGTFEEVATQLHLRDCEEHARGVTTFDWNGEFGLAWVNWDGPHRLMTRSKNGTWKDEATPGFAFPSSVRTLIAADFDNDGNDELFLNHVGEPNRLFRVEPTLVHEETKLSLTMLDAGAAIDAEGFGTGAAIYDIDGDGVLELLVARGEKAAQPLAVFKARAAHPNWLRVRPLTRFGAPARGAVVRAEYGGRVRVKGICGGSGYLCQMEPVAHFGLGTASSVDRVTVTWPDGTGVVVLNPGGNRVLTVPYPRG
>NZ_CP011271.1|WP_082839580.1|2713004_2716691_+|prolyl-oligopeptidase-family-serine-peptidase
MLRTAAAFLLVALPSLAPAQSLQTVAEKSDYKSTSRGADVVQFCEAIAQRGPVARLDYFGTSHEGRKLPLLVISKDPVATPEDAKKSGKLVVLAFANIHAGEVDGKEALLAFARDLTDKKDHPLLKDLVILLVPNLNADGNEKIDPKNRPGDNGPPNGAGTRANAQGLDLNRDFVKLESPEIRALVKLIDTWNPAMVIDCHTTNGSKHRYTLTYDGPRYPATDTDAATWARATLFPAVTKHVKDATGFDLAPYGNFNRDRTKWETYPATPRYSIQYFALCGRVGILSESYSYATFKDRIDGTKAFVTACFTVAAEKRQELVKIAQPIKSTRVTLRTKTEMFPETTDILGFEEIEKDGKRVATDKPKTYPLHFVGRVTPTEFTELPFAYLIPATETTVIETLQRHRIKVEELREDIDLDTESLLVSRVETQPSGSPNRRFVVEVGGEWKKKKRRVPAGTVVVKTGQSLGVLASYLLEARSEDGLTTWAFFGDKLVAGTDFAVQRLAKSYPMALGSVRALPETRRADQPVTEALLMGTGGTFTFGFAGIPLSTGAWVDAEHFLQVKEGKLLKVEARTGRAEPFADPALIKKSLAAIKDLDTKIVESTAKSTSFRTNPDRTAFLFDIGSDIGIAYFDGRPGARLTKSSGAKEHVSFAPNGKTVAFVRENNLFAVDVEKLEEKQLTTDGGGEVFNAKGDWVYEEEIFNRDGKAYWWSPDGAQIAFLRFDDAPVRKFNLVDLQPVRGNLESYAYPKPGDPNPLVKIGIVSVGGGKPVFVDMGAYKPADTVISRVGWVAESKTVFAFVQNRTQTWLDFVTWAAPDAKPKTLFRETTKAWVDDPGEPRFLPDGSFLFLSERTGWKHLYHYSAGGKLIAPITKGDWEVRDVLRVDGKEKTVYFTAGLTSPTGTDFCRVQFGSDTELLSEKGQTHRVSLALSGGLFVDRFGDAMTPTRSNVCEVGKGAVRKLDTNPVREREEFRFGKYERVKIELKDGFVLEGAITYPPNFDRTKKYPVWLFTYAGPHSPTLRDEWGGGRIMEQSLATSGVICFRVDPRSASGKGVQSAWTCYKQLGVQELKDLEEAVAWLAKNPYIDTTRVGISGHSYGGFMAAFALTHSKTFSAGIASGPVTDWALYDTIYTERYMLTPKENPDGYAKSSCVAAAKELNGKLLIVHGMMDDNVHMQNSVQLADALQKAGKDFEMMLYPRARHGIGGGHYLKLQLDFIRRTMGVNK

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Crispr_ID: NZ_CP011271_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_8

2951571-2951669

Orphan

Consensus_repeat	Method
TCTGGCGCACCCCGCGCACCTTCTTCTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_8

>merge|NZ_CP011271|8|2951571-2951669|CRISPRCasFinder
TCTGGCGCACCCCGCGCACCTTCTTCTTCAGTGCCACTCCTTGAGCTTGTTGTGGGAGATGTCGCCGACGTTCTGGCGCACCCCGCGCACCTTCTTCTT

>NZ_CP011271|8|8|2951571-2951669|CRISPRCasFinder
TCTGGCGCACCCCGCGCACCTTCTTCTT	CAGTGCCACTCCTTGAGCTTGTTGTGGGAGATGTCGCCGACGT
TCTGGCGCACCCCGCGCACCTTCTTCTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_157469461.1\|2940165_2945643_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082839714.1\|2929013_2929535_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082839720.1\|2946881_2947706_+\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|379129
NZ_CP011271.1\|WP_157469459.1\|2934578_2935619_-\|AAA-domain-containing-protein	unknown	unknown	gnl\|CDD\|223786
NZ_CP011271.1\|WP_162271677.1\|2945786_2946842_+\|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|379142
NZ_CP011271.1\|WP_162271680.1\|2956185_2957301_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NZ_CP011271.1\|WP_082839716.1\|2937506_2938682_+\|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|379142
NZ_CP011271.1\|WP_082839733.1\|2961685_2962621_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_162271678.1\|2947780_2948272_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379282
NZ_CP011271.1\|WP_162271679.1\|2952543_2952981_-\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NZ_CP011271.1\|WP_082839717.1\|2938717_2939998_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082839728.1\|2957957_2958392_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NZ_CP011271.1\|WP_157470402.1\|2960872_2961271_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082839730.1\|2958723_2959215_+\|DUF2924-domain-containing-protein	unknown	unknown	gnl\|CDD\|371394
NZ_CP011271.1\|WP_157469463.1\|2953024_2956189_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NZ_CP011271.1\|WP_082839734.1\|2962750_2963065_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_157469460.1\|2935615_2936734_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082839729.1\|2958468_2958678_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082839722.1\|2948288_2948831_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|315923
NZ_CP011271.1\|WP_082839731.1\|2959211_2960834_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|214861

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_082839720.1\|2946881_2947706_+\|IS5-family-transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	3.30376e-32
NZ_CP011271.1\|WP_157469459.1\|2934578_2935619_-\|AAA-domain-containing-protein	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	1.71292e-13
NZ_CP011271.1\|WP_162271677.1\|2945786_2946842_+\|trypsin-like-peptidase-domain-containing-protein	gnl\|CDD\|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	2.18397e-13
NZ_CP011271.1\|WP_162271680.1\|2956185_2957301_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	2.52532e-60
NZ_CP011271.1\|WP_082839716.1\|2937506_2938682_+\|trypsin-like-peptidase-domain-containing-protein	gnl\|CDD\|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	5.08256e-11
NZ_CP011271.1\|WP_162271678.1\|2947780_2948272_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379282	pfam13592, HTH_33, Winged helix-turn helix. This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.	2.48152e-10
NZ_CP011271.1\|WP_162271679.1\|2952543_2952981_-\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	3.69499e-12
NZ_CP011271.1\|WP_082839728.1\|2957957_2958392_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	4.68216e-13
NZ_CP011271.1\|WP_082839730.1\|2958723_2959215_+\|DUF2924-domain-containing-protein	gnl\|CDD\|371394	pfam11149, DUF2924, Protein of unknown function (DUF2924). This bacterial family of proteins has no known function.	4.62862e-47
NZ_CP011271.1\|WP_157469463.1\|2953024_2956189_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NZ_CP011271.1\|WP_082839722.1\|2948288_2948831_+\|hypothetical-protein	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.27871e-11
NZ_CP011271.1\|WP_082839731.1\|2959211_2960834_+\|recombinase-family-protein	gnl\|CDD\|214861	smart00857, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.	5.72941e-48

>NZ_CP011271.1|WP_082839722.1|2948288_2948831_+|hypothetical-protein
MAELRQGHPDKEVELWCEDEARLGLKPVARRVWALAGTRPTSNGRHKFESLFVYGFTPPPPSGRSRFLILPKANAELMGQALEDFAGWADPDRRKVLVVILDGSGGHTAKGLRVPPNVVLHRQPSCTPELQPAEHLWPLVREGLANRVFNDLNELTATLTTRCQWLTEHPTVVGGAVGFH
>NZ_CP011271.1|WP_162271678.1|2947780_2948272_+|helix-turn-helix-domain-containing-protein
MTRLPVVPHLTHDEIDQRYRSCSDAAEKTRWHVLWLVTRPDQPLSATAAARLVGFAPAWGRAILKRYNTRGPEALTDGRRGNGAAFKLTPQQQAELFAALQKPPLDHGLWSGPKVAAFVRDRFGIVIVKQTGWQWLKELGFRLVVPRPRHPKAATREQQKEWL
>NZ_CP011271.1|WP_082839720.1|2946881_2947706_+|IS5-family-transposase
MRTSSYPSDITDEQWRLIEPHIPVYPGNRPRTTDLRDVVDAVFYILRTGCQWRYLPKDFPPKSTVWRYFDEWRHNGTLDTIHDRLRTKVRTQEKPYSPRTTASVDSQSVDTTSGGEQRGRDNAKNVDGRKRHIVVDSMGLLLAVLVTAASVDDARAAQQLFPRLEGQPVGQVVRMYADSKYHNFALYEWVKDNARWDLVIVRRPEGSKGWVKLPIRWTVERTFAWLGTCRRFTKDREESVRSSEAFIKLAMIHLMLNRLHPKDNEAEFQYRSAA
>NZ_CP011271.1|WP_162271677.1|2945786_2946842_+|trypsin-like-peptidase-domain-containing-protein
MTRTEKVARLVSLVRTIQTESEGASDALRTPVGAPLEDIADLSATRQALEKTFRDPAPELDDDEVAGLEAIVLTRGRPVAFIRDSRYDPLPAPWAHLNADPVRQRLQPLLNSVGRVELPNSSIPYGGTAFVVGPDLLMTNRHVAALFTVGLGTRGLLYNAGNAAIDFRREVGSAATTHVEVSKVVMMHPYWDMALLRVRGLPAAHPALKLSIRPPDELVGRDVIAVGYPALDSRNDIELQNRIFQSTYEVKRLQPGKFRGRESIRSFETRVNAATHDSSTLGGNSGSAVLDPSTGEAVALHFAGAYLKANYAVPTYELARDPRVVAAGLNFSDVVPATNEFDAAWARAGGE
>NZ_CP011271.1|WP_157469461.1|2940165_2945643_+|hypothetical-protein
MLTALPEDVLAPEQRERVVTFLARGAATGTVLDSPQERGIAQGVLNYWTATLYTSNDPSVLKSSPRTHVLADFDEKATDALSAAADAALARLSEGDHEAARRSLLRLVQLKPTGLEFFTVTVPRSALEATGHRESVARAIAALEEVKVLRVDVGAARGDDHIALRYESYIRTWHTLHEWLEERRRLRTAADLWEQNERSDQSLWEGKQLAIVDWYSDLNQIERDFIAASERKRLAMENENRSASDIIIEAFESGRPIVPLIGAGVSVGTGFPSMAGVTTYLAKVQFYIRNVAVNDQIHTEGAPDTTYLRQHGWPELNQLNAEVWRYLYSEREAEGAASQTETEDDERFTRAVKRCQQAFRSCGSDLSTLARKLWVVPNHRVHLITQLQFLENLSDRDWGAAAKLYVRVLTGELSLRGDWYDLLVSLTEGDFDLVAALFSSLGQGRTPAAPHVFLAQLVDALQVRLFLSLNFDPFLETALWAEGHAPGVVEIAKNADLPSQGTIGDRLTVLKLYGGPYGQRIDEAADTNMLHRAARIIPPNALIVVMGFSGYERRVTQVLMGHAKAAKERDTGGPALLWMNYGTTPDKPVNALRSKINEPNNNQLVIRNYSDVSLFLLDVLTRQRLAHPAGRERYRCLPTMPWADHNDESSAPALRERRVLAFYRESDWDLDGSPVSDARGHSDASMAMARFCREMAKTHQTIWVDCEQHHTVDGIVVDVLDSIRRFDPAFPPLLVQAQRAPQPHHVPPAHKRSVERIREALQRGNYILCFDSPETIGRPQTVHHGTPSLTLPEKPEHDRIRRPRQPQNKLIEKFEARVTGFFDFLTSLLTPPHASDIAESFVCVALAPAAPRHLEPGSTPGRTLTHVDDCIKTLKRFCSDNSQFIDIVKVLPAGDRDLNDGTEHVTQPSSEADQPILEKLVSGLLTSTLNPLERGPQAAFIVPMVLSVFRRPRSYLGYLALLKSPGEDPPKHPRNHSRNFWDQLFGPPRHPRTSIDFPCEYMNGMCYLGGGLLWIPRRLHNRAYNRLTDPGHRIAKAIRDGKEAGHGEMYGAVLSLLAAAFLHRRAARYYFSELYEATGDIVAFREYIYHRVSYLRYLCRLLLVTNRWAGSAPPTDLDARLREHLRQAINKYRHLEEDKQLTREVSTWGRLRLGVRSAWFQELKAFRATLSREFETVRQRLYAGTWVSTIDRLGDFDLEEMHHPAAFRTPNQSDDPEGVLCRSELEALMRELDRQKFEARFEMADWSDTLRDQQAVLHAIEGAFASPGRSPDPPFRGGPTDSLREAYTREASFLPPAQNPSPLILDVHAVAHNKANASPLESARVRKALPLNAPAGGPVSESAFEVVQDKSETRFSPFDSAISLTPAGFVYWFVQAVEWADGLSRLARASYEKCASPAGADNQSDEKMTTHQEQARRIASRLGEWLVAVDELTETKQVPPFSEEIRRFLRERLTVLALDLAVDQARFQLDKFNPWLSGRTREGLPLTTHDALGGARWDAIHLFEQARRTIFQDVRTYNKYRAKSLRMVSQADILMSVGSARFLKPIADLNLALRLLHRSRGADPLEEVACYRTKAEALMLWSDALARGTTLPASDQAAARAHFDAPRARLDAARSMIARALEALSQRPRNVPWWLRLCHDRAQWAVVSCVLRVWEARAAPSPDRTAQKSGAPDTKRANLQREFEIDLRYGLDAIRAGIDGLLPVRGDEEDAHKVLQWKGFARLWLSLAQATEAFNVDERSEARESPTARPTERLETHWARMNQAARMPQLCQSWAKARKNSPLDPSDPQTGDYAVLFHAIAPPENNHAMEKFVDNLLAEFKKIPV
>NZ_CP011271.1|WP_082839717.1|2938717_2939998_+|hypothetical-protein
MSPTTGTQIEELRDAIVGAFSEDALVQMVRFNLEKDLFKIVPRGALSTVAFTLITLAEQEGWTRALVTAVAQVRSGNEAVQRFCRDHAPWALAPPNPQDMIGAVTDGAQALARGGADAQARAIIATFQVELQGGLREFDALHRYKALHDRLHTLEFRYFRDVRTAVEPAAPGGRPRFRDDEEQFLALQRYCTLLRREVAAARADASGLRVRALEDDWIDDYDRAVTYLSAALEGPDDKLARRAVEILKGLFGQASRLNSNMALCAGNLPLGRLTEALRQIIGGLPGSTHQLIKGLQSLQALDPRLQGLIQEHCEWQRLDREFAAAADLPGVTLGETFPHWPRVRGGVMRLCDLAREQPWAVQLRQTVDVLEATTDSVAFRRTFQKFRDLAGEQFYVVDQEMHRLSGHLVEVAQPLAHLLIPNPIDP
>NZ_CP011271.1|WP_082839716.1|2937506_2938682_+|trypsin-like-peptidase-domain-containing-protein
MNTLTGFDLERVRDLLADTFDGHSFDEMLLFDLNITRSRVVPDGAFNTVVLNVLLLSTREGWVPRLIAAAAKRRPGRPDVQELAKQYAATLVAQIKDPQLAGNPQLRQAYRDLNPDKAWFPAEQELKGFEKTIDPENPYLNMAEWVARLARIEGRVCRVEIGGAPRGTGFLVGPDAVLTNHHVVASAIGNAAVLAQLQFRFDYKQLANGTILSGMLVGAAAVLESTPCTPGERTGHPEAADPDTEHLDYALVRLVSPIGDQPIAVPGAVAVGPRRGWVRLPECLSPEGDPFAPGGAVLIAQHPAGEPLRLAIGWQSVIEANGTLTRVKHRTNTSGGSSGSPCFDRFLNPIALHHYGDPMYPEARFNQGVPLMTVRARLAQVHAAMLSGACD
>NZ_CP011271.1|WP_157469460.1|2935615_2936734_-|hypothetical-protein
MVARLHRSCLPHRAVTRLLPGDKPPHECAAELLYFPIDSQTRYTPVLAFVRELRDVYPTRAPYLNDWLRDAREWIAADAGLETSELSDLSPDVITGAAGTLVCVISPDDSRGERWGLRSWLYGPPTGPEQHHTIRSLGEGGVLGTSGAFMRDLSDLMRATLDEVAEHTAAAVSIDFFVPRGLRHIAIDQCLIPAPMTGQTRLLGVEYPVVLRCVDRATAAGANRARAAQIRRTVHLLSGVVHEFTTARHTEDPSRVLAAGHDIAAVLVGEPVPADTGTEAPEFFTRVIEDGVPIILWSRSGPEPAAVLRDLVAGGLGGLPRRIWDYRRGHPGASSDARLREHLSLVYDPADEVSSALRPRRATGPAGRSVQP
>NZ_CP011271.1|WP_157469459.1|2934578_2935619_-|AAA-domain-containing-protein
MNEPEPTVGPQPWHAFDGPGNIDERLARLGEPPPWRDFRTRRQRLARTYKLEDRERNAVNAALHLRRPLLVTGPPGSGKSSLAYAVADNLGLGDVLRWPINSRSTLAEGLYTYDAIARLRDVQACSGADPAGAQPTAAIGRYIRLGALGTALCGWADSEPNPPSRPRVLLVDEIDKSDIDLPNDLLHVLEEGEFEIPELARLANYEGLLETEVGTADRVSAGGTRRRVRVENGIVQCRVFPFILITSNGERDLPPAFFRRCLRLDFPPRADQARLRQLVEAHFGTAPPPVHLTEQVIDRFLAQQGDRNLVANDQLLNALYLVMKPGVPVGTGADALLTLLLRELNK
>NZ_CP011271.1|WP_082839714.1|2929013_2929535_-|hypothetical-protein
MVAGQCMRSLKKLGLSNEIDRFLTKLHSEVLGGASTEDLRKKHQAKPETWGAVLQTLLNLAGGWLQFGRKDRADPILDAARNELFNSNAVTLPPKDYTKLAQAYVTALGQGQAESALARMIELFKRMSPAKITNTWTTAQYYSWFHFWLVEDTVASICEFFGHPLSYTNPDRH
>NZ_CP011271.1|WP_162271679.1|2952543_2952981_-|winged-helix-turn-helix-transcriptional-regulator
MPKPVTSIETIAACCIAGRLRLLNRVVTKLYDDALRPLGLKASQLNILILTAKLGLARPGQVCEILQLDASTLSRNVKPLQAHGWMEVVPGKDARAQPFRLTPKGERLIEKAVPAWEEAQRRASDLLGNEGTSLLDKAARKLGMP
>NZ_CP011271.1|WP_157469463.1|2953024_2956189_-|efflux-RND-transporter-permease-subunit
MSTLNLSAWAVKHPALVLYLIFAAAAAGLYAYLGMGRAEDPSFTIKTMVVSANWPGATSDEMQRQVADKIEEKLQETPYLDYLRTYTLPGKAVVTVQLRNDTPPKAVPDIWYQVRKKVGDIRHTLPENVTGPFLDDEYGDVYVAVYAFTGSDFTPAELKRIARNARQQLLRVKDVSKVVLVGERPEKVFVEFSHKKLATLGVGPQQVFDSLRRQNAVNPAGSVETPTDRVYVRVDGPFAAAEKVRAVPVHAGGKVFRVGDIADVRRGYEDPPTFTVRHNGKPAVEVAVAMRAGGNVLELGRALETEFRAIEADLPAGAAAERVAFQSHVVEESVGEFTRSFVEALVIVLVVSFLSLGFRSGVVVALSVPLVLAITLVVMNAAGMALDRISLGALILALGLLVDDAIIAVEMMVVKMEEGLDRVAAATFAWSSTAFPMLTGTLVTVVGFLPVGFAKSTAGEYAGGIFWVVGIALIASWLVAVIFTPYLGVKLLPSYANRPHHDPYHTRMYRILRWIITACVRHPRSVVAVTAVLFAAAVYGMAFVPKQFFPQSSRNELMVELRLPGGSSFTATEAEVAKLEAVLADDPDIDHFTAYAGAGPPRFYMALNPDLPDPSFAKVVIQAKSPEARERLRARLQERFASDTEFALPRMRVVRLEFGPPVGFPVQFRVVGPDPAKARAISYRVRDIVRQNPNARDVQLEWDEPSKVVRLQVDQDRARTLGLTPQEVSATLQTLLTGVPVSQYREGIELIDVVARAVPEERLKLDTLPNLTVLTPAGSAVPLSQVATASYEQEEPIRWRRDRETVLTVRADVADGVQAPDVTAQVLVDLKALKADLPPGYRIDTGGAVEESQKANEALFAVFPAMIAVMLTLLMIQVQSFKKLFLVFIISPLGLIGAVSALLLFHAPFGFNALLGVIALAGMDMRNSVILIDQIEHDTANGMSLWDAVIESAVRRARPVVLTAATAILAMIPLTRSVFWGPLAVAIMGGLSVATFLTLGNLPALYVLLFRVKQPTDPLPPPAPRPEANDRAGSTEAGVVPLVSADEAPMSVSR
>NZ_CP011271.1|WP_162271680.1|2956185_2957301_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MNTQNRFLVAAGILGLVVGSGGGAYMVYSTPPTTPPPAPAPLPRAARVQEVTTDASASVHTYTGIVRARYETDLAFRVGAKIVSRHVEVGQRVAAGTLLFRLDATDYRLAVKAAEADLTAAEAEVAQSVAEHNRQLQTYQSGVGSTNDLDRARAAKDVAAGRRDRAKENLGIARNRLAYCELTADADGVLTALPAEAGQVVAEGQVVARLARDGEREAVVSLPENQAIGARTARATVALWSAPGESYQATLRELSPAADPVTRTYQARFTIRDPGAKVTLGMTATVHLSPVGATAGYSLPLSALHRAGDRPGVWIVERSTGRLTLVPVDVREYRHETVILSGGVKPGQLVVTAGVQKLDPGVTVRAWKEMP
>NZ_CP011271.1|WP_082839728.1|2957957_2958392_+|TetR/AcrR-family-transcriptional-regulator
MGRARATTSAARRRFLEAADRLFYQHGVRTVGIDRVIAEAGVAKMTLYTHFPSKDDLILAVLQHHERTDLEFFRSTMERHDQKPPHRIEHLVQRALPPARQRPAIFSLRHSGSVDAESEPRSSGDRHLDRTSLNTSNSFGVINR
>NZ_CP011271.1|WP_082839729.1|2958468_2958678_+|hypothetical-protein
MPSTRNPATLTPNERTRELARLLATGLVRLGSELLAPPNGTLPISEKSAESSPNGLAVVPQKSVTVTAG
>NZ_CP011271.1|WP_082839730.1|2958723_2959215_+|DUF2924-domain-containing-protein
MQINVSRELAALARFTIAELRARYADVFGEPTTTGNRTWLVRRIAWRLQVLAEGDLSQRARARAAELARDADIRLIPPKGSTAHAGPVHTGTVPREASDARLPPPGSVITRIYKGTTIHVKVLAAGFEYDGHTFPSLSAVAKAVTGTHCNGFHFFKLNRPERA
>NZ_CP011271.1|WP_082839731.1|2959211_2960834_+|recombinase-family-protein
MTTHTNRLNRPQPKPKPADREPTRSVRCAIYTRKSTEEGLEQEFNSLDAQREAGEAFVRSQAGEGWVVLGTRYDDGGFTGANTDRPGLHALLADIADGKVDCVVVYKVDRLSRSLLDFAQLMRTFEDKKVAFVSVTQQFSTATSMGRLVLNVLLSFAQFEREIISERTRDKIAATRRKGKWAGGHLVLGYDIDPAGYKLTLNPAEAERVRQIFALYLEHGALLPVVEELERRRWTTKRWATRKGPERGGKPFDRTNVYNLLTNPLYTGHVRYKDEVHEGEHPAIVDPGVFAAVQHALARNGRTGGALVRNRFGALLKGLLRCGPCGAAMTPSHSTKGTTRYRYYVCTHAQKRGYGTCPSKSVPAEPIEAFVVERVRAVGRDPELLRQVLEQAREKSTTRISELEAEHGSLEKDLRAWHREVTQLAGQLNPGDVNGPLVTRLADLHARIGTAEHRAAKVREHIRTVTDQLISEEDAARALAAFDPVWATLTPLERARVIALLVARVEYDGSTGAVTVSFHPTGLTALADELSRHHDHRSIA
>NZ_CP011271.1|WP_157470402.1|2960872_2961271_+|hypothetical-protein
MTVAGTIHFARRGRTKELRAGPAPIPHEPGRVPRVSRLLALALRFEDLIRAGEVTDHAELARLGHVTRARVSQIMALLHLAPEIQEHILFLPKVMRGRDPLILSDLRPIAAVPDWRRQRKMWAELGTKRTGA
>NZ_CP011271.1|WP_082839733.1|2961685_2962621_+|hypothetical-protein
MLTRAIAGALGFRPEPVSESGERGATHLGSFTSADGTRYTCLLALTTTANELRALISRLRTRWTEPLLLICTSPSVVTAVGPDLRRSGVRLVPLETLVTADGPGHVRPVSPLEASITWTATAFVPGSIRDRAPNALWHAGEAWSVTFAGKTVLLHDRIGLWYLSHLIQAKGKGFRASELRDRVHGRTGSEPFPGVEAVDQRAAADDERVYRELLEELDEARKDHDPARVERLQEQLHMVTARVQEARGFGGRVRRAGDESTSVRTSIKNAINGIIGKLRKPLPELARHFRGFVQTGSVLCYAPDPDVDWEA
>NZ_CP011271.1|WP_082839734.1|2962750_2963065_+|hypothetical-protein
MSTHKSALSTPRQRLIELLQRLNFGRVEHLRVRAGEPVLDPPPATVREHKFAGENGPRPEAGRPDVVLKAQHLDLMALLDAIGNGTVTVLTVKHGLPFSAEVPG

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Crispr_ID: NZ_CP011271_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_9

3686478-3687133

Orphan

Consensus_repeat	Method
ACGCTGACGGTCACGAACAGCACCGT	CRISPRCasFinder

8 spacers

The CRISPR arrays of NZ_CP011271_9

>merge|NZ_CP011271|9|3686478-3687133|CRISPRCasFinder
ACGCTCGCGGTCGCGAACAGCACCGTTTCGGGCAACGTCGCCAGCGTCTACGGCGGGGGGATCGCGAATCTCTCCGGCGGCACACTGACGGTCACGAACAGCACCATCACTGGGAACAAGGCGAACGGTAGCACCAGTGTGGGCGGGGGGATCGCGAGCCTCTACAGCACCACCTTAACGGTCACGGGCAGCACCGTGTCCAACAACGAGTCCTGGATCGGTGGGGGCATTGATACCGAGTGGGGTACGGCGACGGTTACGAACAGCACGATCACCGGGAACACGGCCAGCGACCAGGGCGCGGGCTTCAGCAATTTCCAGGGTACGCTGACGGTCACGAACAGCACCGTCTCCAACAATACGGCCGCGAACTGGGCGGGCGGCATCAACAACTTCATTGGCACGCTGACGGTCACGAACAGCACCGTTTCCGGTAACACGGCCAACGAGCAGGGCGGGGGCATCCGGAGCTATCAGGGGCCGTTGACCGTTACGGGGAGCACCATCTCCGGGAACACGGGGCGGATCGGCGGCGGCATCGGGAGCTTTTCCGGCGTTCTGACGGTCGCGAACAGTACCGTTGCCGGGAACACCGGAAGTATCGGTGGTGGTGTCGACATTGAACAGAGCACAGCGACAATCACGAACAGCACCAT

>NZ_CP011271|9|9|3686478-3687133|CRISPRCasFinder
ACGCTCGCGGTCGCGAACAGCACCGT	TTCGGGCAACGTCGCCAGCGTCTACGGCGGGGGGATCGCGAATCTCTCCGGCGGC
ACACTGACGGTCACGAACAGCACCAT	CACTGGGAACAAGGCGAACGGTAGCACCAGTGTGGGCGGGGGGATCGCGAGCCTCTACAGCACC
ACCTTAACGGTCACGGGCAGCACCGT	GTCCAACAACGAGTCCTGGATCGGTGGGGGCATTGATACCGAGTGGGGT
ACGGCGACGGTTACGAACAGCACGAT	CACCGGGAACACGGCCAGCGACCAGGGCGCGGGCTTCAGCAATTTCCAGGGT
ACGCTGACGGTCACGAACAGCACCGT	CTCCAACAATACGGCCGCGAACTGGGCGGGCGGCATCAACAACTTCATTGGC
ACGCTGACGGTCACGAACAGCACCGT	TTCCGGTAACACGGCCAACGAGCAGGGCGGGGGCATCCGGAGCTATCAGGGG
CCGTTGACCGTTACGGGGAGCACCAT	CTCCGGGAACACGGGGCGGATCGGCGGCGGCATCGGGAGCTTTTCCGGC
GTTCTGACGGTCGCGAACAGTACCGT	TGCCGGGAACACCGGAAGTATCGGTGGTGGTGTCGACATTGAACAGAGC
ACAGCGACAATCACGAACAGCACCAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_052557574.1\|3677977_3679270_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|224196
NZ_CP011271.1\|WP_052557572.1\|3679440_3680934_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052557576.1\|3675586_3677812_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP011271.1\|WP_082840179.1\|3700321_3701734_+\|DUF3488-domain-containing-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082840176.1\|3695296_3696319_-\|flippase-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|377103
NZ_CP011271.1\|WP_052557559.1\|3692651_3694157_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_157469520.1\|3682675_3684004_+\|phosphomethylpyrimidine-synthase-ThiC	unknown	unknown	gnl\|CDD\|236451
NZ_CP011271.1\|WP_052557570.1\|3681384_3682398_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237057
NZ_CP011271.1\|WP_082840178.1\|3699144_3700281_+\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635
NZ_CP011271.1\|WP_082840175.1\|3691378_3692497_-\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP011271.1\|WP_082840169.1\|3673625_3674384_-\|NAD-dependent-deacylase	unknown	unknown	gnl\|CDD\|234777
NZ_CP011271.1\|WP_157469522.1\|3694156_3695167_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133030
NZ_CP011271.1\|WP_052557554.1\|3698179_3699148_+\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NZ_CP011271.1\|WP_052558871.1\|3674533_3675337_-\|inositol-monophosphatase	unknown	unknown	gnl\|CDD\|334090
NZ_CP011271.1\|WP_082840171.1\|3684415_3685606_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082840174.1\|3689332_3691270_-\|sigma-54-interacting-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NZ_CP011271.1\|WP_082840173.1\|3688399_3689071_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_157469519.1\|3681042_3681192_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052557556.1\|3696422_3697976_+\|S1-RNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|235851
NZ_CP011271.1\|WP_082840168.1\|3672742_3673618_-\|bifunctional-5,10-methylenetetrahydrofolate-dehydrogenase/5,10-methenyltetrahydrofolate-cyclohydrolase	unknown	unknown	gnl\|CDD\|223268

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_052557574.1\|3677977_3679270_-\|ABC-transporter-permease-subunit	gnl\|CDD\|224196	COG1277, NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only].	0.000416857
NZ_CP011271.1\|WP_052557556.1\|3696422_3697976_+\|S1-RNA-binding-domain-containing-protein	gnl\|CDD\|235851	PRK06676, rpsA, 30S ribosomal protein S1; Reviewed.	3.75381e-100
NZ_CP011271.1\|WP_052557576.1\|3675586_3677812_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.68759e-93
NZ_CP011271.1\|WP_082840176.1\|3695296_3696319_-\|flippase-like-domain-containing-protein	gnl\|CDD\|377103	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region. LPG_synthase_TM is the N-terminal region of this family of bacterial phosphatidylglycerol lysyltransferases. The function of the family is to add lysyl groups to membrane lipids, and this region is the transmembrane domain of 7xTMs. In order to counteract attack by membrane-damaging external cationic antimicrobial molecules - from host immune systems, bacteriocins, defencins, etc - bacteria modify their anionic membrane phosphatidylglycerol with positively-charged L-lysine; this results in repulsion of the foreign cationic peptides.	5.15013e-11
NZ_CP011271.1\|WP_157469520.1\|3682675_3684004_+\|phosphomethylpyrimidine-synthase-ThiC	gnl\|CDD\|236451	PRK09284, PRK09284, thiamine biosynthesis protein ThiC; Provisional.	0
NZ_CP011271.1\|WP_052557570.1\|3681384_3682398_+\|hypothetical-protein	gnl\|CDD\|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	0.00991003
NZ_CP011271.1\|WP_082840178.1\|3699144_3700281_+\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	3.52318e-21
NZ_CP011271.1\|WP_082840175.1\|3691378_3692497_-\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	5.50686e-15
NZ_CP011271.1\|WP_082840169.1\|3673625_3674384_-\|NAD-dependent-deacylase	gnl\|CDD\|234777	PRK00481, PRK00481, NAD-dependent deacetylase; Provisional.	9.0055e-115
NZ_CP011271.1\|WP_157469522.1\|3694156_3695167_-\|glycosyltransferase	gnl\|CDD\|133030	cd04187, DPM1_like_bac, Bacterial DPM1_like enzymes are related to eukaryotic DPM1. A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily.	5.13967e-83
NZ_CP011271.1\|WP_052557554.1\|3698179_3699148_+\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	3.71645e-92
NZ_CP011271.1\|WP_052558871.1\|3674533_3675337_-\|inositol-monophosphatase	gnl\|CDD\|334090	pfam00459, Inositol_P, Inositol monophosphatase family.	1.17761e-52
NZ_CP011271.1\|WP_082840174.1\|3689332_3691270_-\|sigma-54-interacting-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	7.31409e-139
NZ_CP011271.1\|WP_082840168.1\|3672742_3673618_-\|bifunctional-5,10-methylenetetrahydrofolate-dehydrogenase/5,10-methenyltetrahydrofolate-cyclohydrolase	gnl\|CDD\|223268	COG0190, FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism].	2.75459e-135

>NZ_CP011271.1|WP_082840171.1|3684415_3685606_+|hypothetical-protein
MNLDAVIFVPALTGSVIVGFAFLMFAAHYYLSVLEGTAAGAKEIPWEGDAITNNFIKVFYLAWLMGLWAGPAYFVGRAIASGSDAAWIKLAAPLLVIWVLYPLSQLASLSASSVWVPMNLDVFARLAQKPLVTVGFFALTLPVFALIGIAFKWAYMTRGEFPLLFMGVPLLCFAVLLYARLLGRLAFALMFTKNLFKRKKKKKPKREVEEFDAEPDEEAPPPLQPSEMAPINTPDGELAGYNVLMEDDPPAPKKRVKAVVVEDEPEVLEPEPVLRLAPEPPPLPAHVKRTTDRPLERARVWGDEDDDSTPYTMNPSEVKDEERIPQEVVKPRADEMALLDRRDAPKPPKVVWSWELLAFLLQPGTISALITMSGLGVLAGVFVRVARAFDPTLGSE
>NZ_CP011271.1|WP_157469520.1|3682675_3684004_+|phosphomethylpyrimidine-synthase-ThiC
MTQLESARKGIVTPEMEFVAKREDLHPELVRAEVARGRMVIPANTVHLAKGLQPMCIGVAARCKINANIGNSAVTGKADDELEKLRTAVELGSDTVMDLSTGGNIDGIRQAIIDASPVPIGTVPVYQIIQNVKDPRDITPRQLLDMVEHQAKQGVDYMTIHAGVLLEYVALTSERVTGIVSRGGSLMAGWMVAHHQQNPWFTHFGELCEIMRKYDVTFSLGDGMRPGCLADANDKAQFSELKTLGDLTLKAWEMGCQVMIEGPGHIPMHLVKMNIEKERELCHDAPFYVLGPLVTDIAPGYDHITSAIGAALAAEAGASMLCYVTPKEHLGLPNKDDVRQGVIAYKIAAHAGDIARGRKNVRDRDDALSKARFEFDWNRQFELSLDPETARRMHDETLPQDVFKSAKFCSMCGPKFCSMRITQDVRKLAADAKKLSLELAVV
>NZ_CP011271.1|WP_052557570.1|3681384_3682398_+|hypothetical-protein
MRITRFLLPGFVVALSVGPALAQPQSRGGAWSDYPGLVPSVRPVGAEEPAFTGSSMPPGRPPAAVMSLEQMGGATGSGAADPMGTLTGQPAPGALPPGSYPSPYYTDGPGCCSPLERAGRIGYEGYSYAGLNFTIGNGLPDLLKTTGWTVGGGVRTLFFNPTHTAAWTVDLGGSYTYNRGQGENEPTFLFLRTAAVQNQTNGGFQVQPDRFVLTAVRGISRSSFNYAFGRDVWLLGDGSTAGQSGTNWRIGGWVGGRYGTAHVDMVPLDETNGYSRRQNVYQGVFIGAHTTFDIPMGSWIWTNGIRFEYGYDWTNLVPPVQGNLHNLNLQFTTGFRF
>NZ_CP011271.1|WP_157469519.1|3681042_3681192_+|hypothetical-protein
MQLGSVNPARKGGGWSARAVGESHGAVIKDGVGSNDPPPFTNNHLRGWN
>NZ_CP011271.1|WP_052557572.1|3679440_3680934_-|hypothetical-protein
MDPIELRDLDAARRYILDGLLLQRALKPTAKTVRPALEWAMEIASSGHPLPPIGFVADVGNVALGVDAEQRVRDAHPVPGWPPALGRSYEDHVLGKLYADWTFERAGDALRKYKEKDRVRGLAYIVNQICEHAGITGVLLPPAVIRALQSTNPDEVVQTAYDGLVRDGPSPLLVQMYEALVSAGRRLAEVLAPEDVIALEQGTALADMGQYVAHRQILQTTARIEARLPARPVKPLVGRKEVPTRVLDEDQYPVGGYTSISTKGSIESLLHSQLAYMEDESPDLFDMKFVRDELFYYSRDENQFLRRRRAFVFVVFPDLIAARFKDSELPYQRIVMLQSTILALVRKLTDWLSTDAIRFEVLFVQDGGKAPLAEEAALLRLLLREPIERGDGLVATGDRTASGKNTPEQEAAERGTESREAVMTYLNRLSRNSQVHCLAIATEPFDMEMENVVVTELVVAGPRPEIGAGDGAVAALDGEEPFDVWQESVMRVLQLWV
>NZ_CP011271.1|WP_052557574.1|3677977_3679270_-|ABC-transporter-permease-subunit
MFSMLFNDPTVLLAGVVLATVQFVAALPWLWAIDPKGFKSAASSPASLGYAILGLLVAGGGAGAFLVYKGDPANLAVNGRYIYGGLLHLQLIVDLFLLLPQIVMILWPKGGVVAFAAYRESCRQPMFWLVTLGATVAIWISVTIPYFTFGDDYKFMKQIGFDLVMLAATLFGVLAASMSISEEIEGRTAVTLMSKPVNRRQFLIGKFLGIVMACLIMSMLLNWSLTYALRANREYDTINNAADPTDPLAAPTDKVVDPMTYQAQKTVVPPFKRVVPSVPGKAVATGAGLWFSDAVAHTFGVMLGFGQVMILVAVASALATRLTFIVNLVLCLLVFFLGHLAPVIVQVTQQAQAQGGAGVGVGLVGFLGRLFDALLPSLESFNMSRAIIRETELNLWQFGVYVLTVTGYSLIYTVIALLGGLLLFEDRDLA
>NZ_CP011271.1|WP_052557576.1|3675586_3677812_-|ABC-transporter-ATP-binding-protein
MGSTALAQIHSSFVKSPSARWGSLLCSVGAAITYVLLLLLLYLFVDLLVWRGEIPTYAQLSAARKREFADEWATRSDADRAEAVARLGWPVHRAKRLETRTDDDLKPIAKAPAEEHLFADEWDARWHAGVYLALRDRVNQSAADNYLPPPGWERADKADSADPEARPQFGVLSLVVRERNRWTGPVLGWVASWNPWTWAPGPKGSANVPYLTGLFILAFGIAAVRGILVNALTYVSAAVTLDAIIRLRRAVYFHSYRLGPITMQTLGTEEVANLMTRRVEEIGAAIQAQFASTVRYRLLVVLLIGLIVLVNFWLALSFLALAALVWLVGGQVAAHFRREGRIGERQAATTLALLKESMSLFRLVKCFQMERFNQNRVERQLAESARANWRRLRGGEMAGPLLNSVVVLTGVALLYLAARGVLAGGFSVAGLAVLTVALVSLAIPIAGLFDRALKVRRGREAADAVFEFLERRGEAAEAADAEFLPGLTTRMEFRHVTLNDPATGETILKDVTFAVPAGASVAIVGQNAAEKHALVSMIPRFLDPTSGEIRIEDKNIRWVTHESLRTQVALVMQDDLTFTDTAANNIGVGDPSHNLPQIIEAAKLAHAHQFIEKLPFGYETLIGNGGHSLTPGERFRIALARALLRDPSILIIEEPTGPVDEDTLALLDDTLVRVSAGRTVLFLAQRLSTLRNVDRVFLLKDGLLEADGAHDDLWKSNDSYRRLQILADATATEHPVLKTDS
>NZ_CP011271.1|WP_052558871.1|3674533_3675337_-|inositol-monophosphatase
MTFQDELAAAREAAARASDLLRREYEHFTAIPDAPVTISTHADKASQELILGFLHDRFPADALCAEESTPAFDSLPKAGRRAWVVDPIDGTRGFAKKVGQFSVMIGFLVDGKPVVGVVAEPAQNRTTFASVGSGCWTHTGTAEPTQCRVSARGFSELVLVQSWAKTGMSPKPVQALAPARVVETYSGGVKLAHVARGEADVYANTYEAFADWDICAGHVLVTEAGGTVTDLSGNPIVYQGENFKQTRGLIATNGPIHAEAITRLAAV
>NZ_CP011271.1|WP_082840169.1|3673625_3674384_-|NAD-dependent-deacylase
MTDAELDAALDRAAHWLRTAERVCVLTGAGVSAESGVPTFRASDGLWEGHRIEDVASPDGWDRNPLLVWQFYNARRANVATVKPNAGHFALVAMEDRWSDRFTLVTQNVDGLHLEAGSRRVLEIHGSLRQTRCLTCGSVTNRGSEPLGDAPECPQCRGRLRPHIVWFGEGLPDDVWSAAMVAAHECDVLLVIGTSAVVHPAASLIPISKRHKAVPAKVIEVNLTPTEASAYADVGLYGPSGEMLPKLLQRLG
>NZ_CP011271.1|WP_082840168.1|3672742_3673618_-|bifunctional-5,10-methylenetetrahydrofolate-dehydrogenase/5,10-methenyltetrahydrofolate-cyclohydrolase
MAAQRLDGKALATTMRSEIAARVTERARAGKRAPGLAAVLVGEDPASQQYVKNKHKACQDAGLASTVHRLPASTTQAELLELVGRLNADPAVHGILVQLPLPKQIDDGAIIRAVSPNKDVDCFHPENVGLLMTGYPRFYPCTPHGVLQLLTRNGIALSGKEIVVLGRSNIVGKPVAVMLMQKATATNPAAGDATVTVAHTRTKNLADVCRRADVLIAAAGVPGVITPDMVKPGAAVVDVGTNNVDGRWLGDVHKDVESVAGWLSPVPGGVGPMTITMLLYNTLDAAKQIDG
>NZ_CP011271.1|WP_082840173.1|3688399_3689071_+|hypothetical-protein
MRIAHIFALLICLFPATQARAAFTVSISSDTVAVGTPAQLNVTITSDAPGGELLDIFGLELRITRVSGTGELRFVDPQSSAELLSSKYVFGADSVNAVTPGADVQITTNTTTHDTYLGGDGTMSGSGATVGSDPRLLVVLDLDTSSTVAGDKYQISVIGSAFTSFYDPALNPVDSSAGTGTLDVRTSGVTPTPAPPSAALALTGAVFWGAVRRLRSRAVPGAV
>NZ_CP011271.1|WP_082840174.1|3689332_3691270_-|sigma-54-interacting-transcriptional-regulator
MAQPPSAFLVARRDDGFGDVFPLHEGTRYKLGRAPTNRVVLRDDLCSREHAEVFAAEGGWFVRDLGSLNGTHLNGETLRTDRALRPLDEVRVGRTRLLFIEEMSQLPDLPKSAIKPVEKVDGLEIRKRLSQTRYQQTGATNVPEPETVRVDARVAPPQAIGVLYRLALDMAAAADTGELCALAVDSVFRATPAEVVAVLALKEPKELELLTHRVRGGGPATYHKVSQFVSSEVLSGKQAVLAENVAANRMLADRDSIAELKVASLICAPIVFDDKVLGLLHLYRTLGHSPLNTDDLEFTLAVARQLGTAWHKLTRQVNLSAENRSLRTQLRIESEIVGGSEPLRKIEGQIARVGETRATVLIRGESGSGKELVARAIHQNSPRHEGAFICLNCAALTETLLESELFGHEKGAFTGATERMVGKFEAADNGTIFLDEIGEMALTTQAKFLRVLEGHPFERVGGNVAIKVDVRVVAATNRPLEEAVRAGTFRRDLFYRLQVVQLDVPPLRERLDDVPLLAEHFLKKFVRETGRKIKSFTPAALDKLRTYRWPGNVRELRNVIERAVALGIGPQLDTADIWLSELDVGAPVVGVVTAAYRPEPLDDVEKRHILETLKHTDWNKSKAATILGIERSTLDRKIEKFGLVK
>NZ_CP011271.1|WP_082840175.1|3691378_3692497_-|CPBP-family-intramembrane-metalloprotease
MSELGNDPPLVTRPEPEVAPLVVRRLPKPGFIEAVLWCVIFIATQLLGAIVAVTVAFTAYALAAPDAKAFVDEQFTAFGKSVDLKVEGERPPIPFEFGQALAWGMLAAQVVSLGLILLVVPRRIGPGWKQQIGVRRPYWLHIVLVLLLVPGFIVMSDLIQTVFLTLTGMKPPAAMKALNGVFGQFPWPLTVLAVAIGPGLVEELWCRGFLGRGLCARNGVVVGVLLTSALFSAMHLDPSQLVVIAAMGAYLHFVYLVTRSIWAPILLHAMNNGLAIFLALAMKPGNEQGEIVVPAIVHIAAFGLLVFGSVALWTSRAVPETVWHTKESGSDAFAPPADVTTRYGYAEVSPAALMFSIVSFSTLMYLGYHFSR
>NZ_CP011271.1|WP_052557559.1|3692651_3694157_-|hypothetical-protein
MAAEPSDMRRSAFLLLAAAAVAIAAAKTVGAENVIEPSRYKAAEKGGYGAEPDRKWPDTRPDPIPTFSSNDKSRWATVRALVHNRTFVIGKRTYPDPKDSTKYKDEGIVAEPAYKSLDIVMNPETKEFYSSKPPLMSVLVACEYWLLNQGFGWDIGKDRWLVIPVIVLTWNVLPLLVYLLLIGKLLDATGKTDFGKLLAFAVASVGTFLLTFTGTLNNHLPAAYCVLFASYPLLRAVAENRDMTPAGYCGCGFFSAAAATFELPALAFFAALFLTLFIARPRSTILFFIPCAALPFAALFAANYAALGKLLPAYSEFGGPWYNFEGSHWAKRGTPAAKGIDFNDEPTTVYAFHLTLGHHGWFSLTPVWLIAFVGLLVMGIKSAPAVQKLFTNKKGTGWTPELFAAMTLVVSVAVFAFYLTRVQSYNYGGNTSGPRWLFWLIPLWVLAIPSAADRLGRSEAGRLLCAALLGFGVLSVFYPAWNPWRSPWILQLMEYNGWVRY
>NZ_CP011271.1|WP_157469522.1|3694156_3695167_-|glycosyltransferase
MPVLSPSPFGIGSASLLSLVIPVFNERESLVALHAEITEVAQKLTERVEMIFVDDGSKDGSWDIVCALAEKDDRVRGIKFRRNFGKAAALAAGFSAARGSVIITMDADLQDDPHEIPHFLDALRGGLDVVSGWKKVRHDPWHKVFPSRVFNKFLSVLTGVHLHDHNCGMKAYRAESLREVYLYGELHRFVPVLATARGFKVGELVIQHRARKFGSSKYGWKRFIKGALDVTTVRLLTGFGRRPNHFLGAWGLTFGSGAVFGLLLLLANLFLRLIDGTLGAGPFTQMVVLILSVGCGLLGAQCLLAGLVTEMTVARKWLDNDPYSVAEHTPTKQEAR
>NZ_CP011271.1|WP_082840176.1|3695296_3696319_-|flippase-like-domain-containing-protein
MSNGKHRKIRLAIETVVAIVIVIAVGWSFHNTLKGIEPGTLPIRVRVELLIPAGVLYLLAHLCWSTFWVRLLHSQGVRVSWWVGLRAYYISQFGKYIPGKVAVLVMRVAMLRHQGAHPIPVAVTATYETLTSMAAGALLGVLFLPTLGVLPPEVSGRTTLLFAVAALPLGLAALNKLAVRIAKKRRGPGAPPLPSPSVLLLAQGLVHGACGYCLLALSLGLTVHGLLPDAPGWGARAFTIDLAAVALCYVAGFVIVVAPGGLGAREFVLRWALAPQFVSALGTEHAGQVAIVVALALRLTWTIAEVVVGLLLYAKKPALPPPVRHDETIPIHHEKSHAKP
>NZ_CP011271.1|WP_052557556.1|3696422_3697976_+|S1-RNA-binding-domain-containing-protein
MSTENTSPTPDQPTPPAVTPAAPVTPASAATPPASGANAPKPGGPAPYAGKGPPRPGAPRPSGPGGPNRGGPNRGGDRPNRSDKPYNPGGAPQQLYVGSTKPNARELDKLIEDELAQAMGDFDVSKTVAAVETVQKPRAAGTVGGGKKTGVIVGVHGNDVFVEVPGGRSQGVLPLQQFEGRKPVVGEAVEFDIDHYDSADGLLILTREGSTQIVHDWSQVAYGMIVEARVTGTNKNKTGLTVEVAGIKGFLPASQLDLYRVENIDQFVNQRLKVMVAEVNPEERNLIVSRRAVQEKEKQAKAEEFWKNVSEGQVLKGIVRSIKPFGAFVDLGGADGLIPASEFSWQRVNDLSEFVKIGQQVEVKINRIDFDARKIGLSMKQLTVSPFEEYAKQVQAGARVTGKVTRIADFGAFVELTPGVEGLIHVSELSTQRVRRVRDVIEEGQTVIVEILSMDATTRRIALSLKKIASEEEAAAEAAEQAEHEADLKAAEEAMANRPVNPNLRGGIGSVIKFDKP
>NZ_CP011271.1|WP_052557554.1|3698179_3699148_+|MoxR-family-ATPase
MPVDGPSNARSPRELAALLDALQKNVGRVFLGKPDIVRFAAVALLADGHLLLDDVPGVGKTLLAKALARSLACKFNRIQFTPDLLPGDLLGVTIYRAQTSEFIFQPGPVFAEVVLADEINRATPRTQSALLEAMQERQVTVDGNTRPLGPPFLVVATQNPHEFEGTYPLPESQLDRFMLRVKVGYPDREAERAILTQHRAGEPVETLEPVLQPADVIALQTYVRTVRVDPSIAEYILDLIGGTRTHPELALGASTRAALAMYRAVQAFAVTAGRDFAVPDDVKALAEPVLAHRLVTRSWAAGGHPDAGPVVREILAKLKVPA
>NZ_CP011271.1|WP_082840178.1|3699144_3700281_+|DUF58-domain-containing-protein
MKRSEGVIDGPQMQFTPAGVAWLGVALVVGAIAWYKSINLVLLIVYVMIALVVLNGILARINVRRASARRLAVGPLFAGERSEYGVRVTNLGRRAVTVAVEDRSRAGTTNFLAYRVRGAKTLDCTASRAFPTRGRFGGPVALVSSFPFGFVTCQLPGDATDEVIVLPTPGVAEPDGLRRWVIRQAGGDGRSRKVLRRVTTDRAEVRGVRGYRTGDPIRDIHWRTTARRGEPMVREYDTAPSPELVLVVEPWLPPTPTPADRDRLEAALSLAATIAVTWRRAFDSPITVVVPGHGAGTAHSEEHMRAALAPLADVTGGPEVEAPSTAVFAGHLARGARVVVSSRPNSPFAGTLARSTGKPFATVCPTDRLPWYQPPKTA
>NZ_CP011271.1|WP_082840179.1|3700321_3701734_+|DUF3488-domain-containing-protein
MPTEATFRFSTYLTLALACVTLGYAQAPMLPEVAGFAVLAVLALGALYFIETRFTLLSIPAANRLGGAVGACFCLWVAYRVKREIDTGEFAHMGWHVLMVAMFGPLVMMLLAAKVARGEKHAGDYWSLHGLALAGVGLAAAFAEEPLCFVLVGLYLVAAVWSLSLFYLGCASGAVPPVPDPNKVVPDAAAASGEPRGTRTGFPSALVWAACAGVVAVPVYLLTPRSSAPKADFGKPRVEIGYAADQMVDLNRTGALKTNSETAFEVTATYPDGAPKTDVSPDQRWRGRTHQQYTGGAWNMEPKRLPNLVRTARQSNPWAAPNLGPGQFTLAFELPPKSKAHFAADPILWLPNQPAPFVGVTEDGDQGWMPTPDGTFYWDPGPRQRNRPLKYRQEYAPRTDTDLGPGFQIADSRLDDSLDQLRINPVERVKEYADKLLVELIEGANSRPSGATRPSSATPNGASRAPSTTT

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Crispr_ID: NZ_CP011271_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_10

3903615-3912171

Unclear

Consensus_repeat	Method
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	PILER-CR
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CRISPRCasFinder
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CRT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	PILER-CR

117 spacers

cas5u,cas7,cas8u2,cas3,cas2,cas1

The CRISPR arrays of NZ_CP011271_10

>merge|NZ_CP011271|10|3903615-3912171|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCGCAACCATCTGGGCGATTTGTGCGTGTGGATGTCTCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGCCGCCACCCGCAGCGCGAGCATGATGCGCTGAATGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCAGTGGTACCGACATCCAGAGTGGCATTCAGTTGCGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGCGGACGCCACGGACAAATCGCTCATCTTCCCGAGCGGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGAGCATGTGCATTTCTAACTGTTGCCGCGGACTGAAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCGCCTTCTTCCGGTCGAGCGCGGCGAGTTTCTCCGCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGGTATCAACGCTCGATTCGCACCCCAGTATCCAGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTCCGTGGCGTCCACGTTAACGTGCCCGCGCATGGTCGCAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCACGTCTATCCGTCTGCAAGACCCCACAAACTGAACGTGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTTCGCGTGTTTGATGAACCCGGTGAACGGCACCGAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCATAAGCAGCATTGATGTAGTCTCTGTTCAAATTTTTGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTCTCCTAGACCTGCTAGGGTCTATATTGCAAAAGATGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTGGGTACTCGATGTGGTCCGCGAGCGCCTCGGACCCGCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCAGGTGCGAACGGTATTTTGGGAGCGGCGAGAAGACAAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCAGCTTCGACCTTGGAACCGGTCGCGAGGTGAACGAGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCACCGGGAAAGGCTGCTCGCCGCACTCATTACCCTCGTGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCCGAGTTCAACTCTCGGCCCTGGTGCTGCAATCACGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTCTACTCAGCGTTCCCCAAACGGGGCTAGGCGCGGTGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGTACACGGTGCCGCACAAGATCCGGCTCGCGACGCGGGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCAGATCGGGTTGTAGTGGACATAACATCTGAATCGAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCGGTGCACCGAGTGAGGATCGGCTCCCGTTTAGTTTGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTAAATGGAACTGGATGAATTCTAACTCTTGATCCAAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCATCTACTTTAATTTTTTCTTCTTTTCGAAAAACATCAGCAACGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTTTGGGGGGAACTGACTAACAGAGTAAAAGTAAAAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCTCGCGGGCATCGGCGTGGGTGCCGTCGGTTCGTTGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTTAACCTTCCCCACAAGCGGATAAAGAGAATAAAGGTAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGGTCCTACCATGTTTGACGGTTCCTATTTACATTGAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCCCGCCAAAGAAGGGCAGGGCGTTAAGGTTGGCGGCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCCCGTCGCGGTTCTCGCTCTCCGTTACCTCGCCGTCCTCACGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCATGTCGCGGTGCGTGAAGTGGTAAACGTGGGTCTTCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGACCCGGCAGTCCCACCACGTCCCGTACGGCGGCATCCAGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGTCGGGATCTTCTCCTCGGACGACGGCCGGGGCCGGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTGATCTCGGACGGGTACACCGCGACGAAGACGGTGCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGCGCCGACCGAGGACCAGTCGAAGGAGCTGCTCGGGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCATGGTCTTGTAGGTCTGTTCCAGTTCGGCCGGCTTGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGGCGCGACTTTCGAGAATCTCGGCACGCCCCTCAAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCTTCCGGCCAGTTCTTTTCAGTCCACGTCTTTCAGGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTTTTCGGCGAGTTCTTCGAGCGTGACCCGATCGCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTCGTTTTGGTCTTCGGCGAGTGCCCATAACGTGTTGCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCTGTTTGGTGCCGCTTCGTTCTTACAAGTCTTCTTTGAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTGCTGAACCTCCTCTAACCTTTCTCACATCGAGGATAGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCCCCTTCTCGCTCGGAAGGGCATCATGCCCAGACTAGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGCGATGGCCCGTGATGACATCGACATGCCGGGCCGCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGAGCACGGGGCGCTGCCTATGGTCGGCTGGAACGTAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCGCAATCTGGTCGAACTGTCCCCAGTCTCCCAGGTTGCGTCTCTCCCCAGATACATCTGGGCCGAATTGAAGCGATGGCCCGTGATGACATCGACATGCCGGGCCGCACTCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCGTACCCACGGTCGTCTAGCTCTTTGTCAATGCTACGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTCCAACTCCTTCTGCTGTTTCTCTATCTCCTTCTTGCGCTGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTGGCCCCGCCGAAGCCCATCAGGTGAAACATTCGTCTGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGGTTCCTCCACCATCACCCTCATTCAAGACGGATGGGCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGACTATATAGGATGGGAAGTGGTTGATAGTGGGGGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCAGCCATTCCTCATAATCGACATCTGCTCGGCATGCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTTGAGCCATTCCTTACAACTCTCTTCAATTAGTTCGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTTCCTACCGTAGAGCTAAGCACATACACAGGGACAGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGGCTTGTTGCGCTTCCGCGGACTTCTTGTTGCCTTCCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCAATCACCAGCCGCTTCGTCGTACAGAACCTTGTCTTGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTTCATTATCACGTCGTTCTCTGCTGTGAGATGTAAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCTGCTGGCCGAGCTGATCGCGGGGCAGTCGATCATCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTCCGACTGTGGTTCCGAAAGTGGCAAGCGCGTGGTCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTGCTGGCGGTGGCTTCCCGACGTGTCAGGGCGCGGACCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCCTCTGGCGGGTTCGGGTTCGGCCATCTCTAGACAGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTCGTACTGGAACCCGGTGACAACCCTCTGGTCCATGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCAGCTCCCCGCCCATCACGTTCATAACGGTCAGGTCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCACCGCCTGCGTCCGGACCGGCCCGAAGTCCAGGCATGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGTGGTCGTCTCCGGTGCGCGAATCCAGCACACCCAGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCCGGACCACGGTGCGCTGGAACGAGAACGACCGCTGGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTTGATCCTCTGCCGCTGAACGTCCGCGCTTACCTCCAGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCTCGGCTCCGAGTCTGAGGTGCAACAGCAGGGCGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCATGTACCCGAGATTGCGCAGCCGAGCGACTGCTTGAGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCAACTCGCACCCGTAAGCTCTCCTCCCTAACTTCAGTGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGGGGACGTGAACGGGGCCGCGGCGCCCGGCGCGACGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGCCGAGGCTATACGCGACCTGAAGACGCGACGGGAATACCTGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCAGCAGTTCGTCGCGGAACGCCTGTTCCTCGCGCGAACTGGTCTCTCCCCAGACACATCTGGGGCCGAATTGAAGCGTTGCAACCATCTCCGGCTTGTACGGGTTGCGACCAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCTTGGCGGCCTGGTCGCGCTCCAGCTGGGCGAGTTGCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGGGTTGTCCGGGGTGACCAGGAGCACGACGTCGTTCCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCGCGTCGGCGCGCTGGAACAGCACGAAGTCGAGTACGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCAACGTCCTCGCGCCGCAGGACCGAGGGGCCGAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCGAAGCCCGCTCCGCTGCCACTCCCAGTTTGTCCAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCACGGGCACCTGCTCCTCGTACCCGGCCAGTGCGACCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCGAAAGGGGCCAGCGCGTGTTCTCGCCACCACCGGCAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCTCGTTAGGGGGCGCAGTTCGTGATCGCCACGTCGACTCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCACCTGCTCGGTGAGGTGCGGCCAATCAAGGTCCACAAGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCGCGCCTGGATGCGCCCCAAACTGCGGCCGCGCTCGCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTCTAAGCGATAGGAGACGCAAGGTGGCCAAAAAGAAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGCTGGGGACTGACGAAGACGGAACCGGCGCTTGACCGATTCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCACTTGATGGGCTTCGGCGGGGCCAAAACAGACAGTAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCTAATGCCGCGGGCGCGGTTGTGCCGGATCGTGCTCGCCATGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGCAAGTGCCTTTTGCGCGTCCGGGTGGCGCGCCCCCATACCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCAGGTCGGGGGACCACTCGGAGACCTGTGCGAGCGCCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTCGCTTTCCTTGCTTCTGCTGCCGTTGCTGCTTGAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGCCTCAACGTCGTCCTTGTCGCTGGCGAGCACGGTCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTGGCCCCCGCGGTGATCGACGGGATTGACGTCGGTAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTGGTCCCGCCAGCCCTCGATCGCCGTCGAGACGACCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCACGAAAAACGGGAACTTGTAATCCGCCCCGAATTCGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCATCGCATCGGAGATCCGGCACACGGCCGACCAGTTCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGTAGCGCACAAGGTTTCTCCGTAAGGGTCACTCGGAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGTGGCAGTTCCGTCGAAGAACATCACGTCGACGGAGGAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCAGCAAATGGGGCAACCGTCAGCGGGAATGATCGTCGTGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCACGACCTCGCGGCACCTCGTGATCGGGCAGCACACCGGAGTGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCGAGCTCGAACGCGGTGTCGAGGACCGAGGCCCCGGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTTCCTGGGCGCACTGTCTCGGGTGTGCGGGTTGTGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTGGTCCGGTTCCCGTTCGCGCAACCTCTGGGCTCGTGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTTCAGGATGCACACGCACATCCGCTTCCACGTCGGGAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCACTTCGTCCTGAATCTGAATCAGGCGAGCCAGCCCTTGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGGGTTAACTCGCGTGTGCCCCAGCCGCCGGCAGTCGGGCCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCAAGGCGTACAACCGGCCTCTCAACACCGCGGGCCTGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTTCACGAGGTGCGACCGGTCCGCGAACGACAGCGCGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCAATCGTAAGAGCAAAGCGTTTGAACTGAGTAATCTGCACGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGCTTCCGGCCGCGCCGCTGGCACCGGTCCGCCACCGTGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCAGTCGGGGGGCTTCCGGGTGGTCGCTCCCGTAACTGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGTCGCGGGCATTACTTTCCCTTGTGTTTGAGTTACCGCCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCTTCCCCCGGCGGCGCGCATCATCGGGCTATGGCAAGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCAATGAGACACGTCCCAATGACATACATCAAGGACCGGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCCGCACGGGCGGGGCCGACGTGACGACGCTCGGCGCGCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGTCTCCCACTAATCACCGTTGTGCCCGCAAACGCCGTGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGTCCACCGGCGCTCGCACACGTTGACCTTTGTCCCGCCCTCGGTCTCTCCCCAGATGCTTCTGGGGCCGAATTGAAGC

>NZ_CP011271|10|2|3903615-3910053|PILER-CR
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGCAACCATCTGGGCGATTTGTGCGTGTGGATGTCTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCCGCCACCCGCAGCGCGAGCATGATGCGCTGAATG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AGTGGTACCGACATCCAGAGTGGCATTCAGTTGCG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCGGACGCCACGGACAAATCGCTCATCTTCCCGAGCGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GAGCATGTGCATTTCTAACTGTTGCCGCGGACTGAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGCCTTCTTCCGGTCGAGCGCGGCGAGTTTCTCCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGTATCAACGCTCGATTCGCACCCCAGTATCCAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCCGTGGCGTCCACGTTAACGTGCCCGCGCATGGTCGCA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACGTCTATCCGTCTGCAAGACCCCACAAACTGAACGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCGCGTGTTTGATGAACCCGGTGAACGGCACCGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ATAAGCAGCATTGATGTAGTCTCTGTTCAAATTTTTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCTCCTAGACCTGCTAGGGTCTATATTGCAAAAGATG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGGGTACTCGATGTGGTCCGCGAGCGCCTCGGACCCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AGGTGCGAACGGTATTTTGGGAGCGGCGAGAAGACAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AGCTTCGACCTTGGAACCGGTCGCGAGGTGAACGAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACCGGGAAAGGCTGCTCGCCGCACTCATTACCCTCGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CCGAGTTCAACTCTCGGCCCTGGTGCTGCAATCAC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCTACTCAGCGTTCCCCAAACGGGGCTAGGCGCGGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTACACGGTGCCGCACAAGATCCGGCTCGCGACGCGGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CAGATCGGGTTGTAGTGGACATAACATCTGAATCGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGGTGCACCGAGTGAGGATCGGCTCCCGTTTAGTTT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TAAATGGAACTGGATGAATTCTAACTCTTGATCCAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ATCTACTTTAATTTTTTCTTCTTTTCGAAAAACATCAGCAAC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTTGGGGGGAACTGACTAACAGAGTAAAAGTAAAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTCGCGGGCATCGGCGTGGGTGCCGTCGGTTCGTT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTAACCTTCCCCACAAGCGGATAAAGAGAATAAAGGTA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGTCCTACCATGTTTGACGGTTCCTATTTACATTGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CCCGCCAAAGAAGGGCAGGGCGTTAAGGTTGGCGGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CCCGTCGCGGTTCTCGCTCTCCGTTACCTCGCCGTCCTCAC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CATGTCGCGGTGCGTGAAGTGGTAAACGTGGGTCTTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GACCCGGCAGTCCCACCACGTCCCGTACGGCGGCATCCAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTCGGGATCTTCTCCTCGGACGACGGCCGGGGCCGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGATCTCGGACGGGTACACCGCGACGAAGACGGTGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCGCCGACCGAGGACCAGTCGAAGGAGCTGCTCGGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ATGGTCTTGTAGGTCTGTTCCAGTTCGGCCGGCTTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGCGCGACTTTCGAGAATCTCGGCACGCCCCTCAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTTCCGGCCAGTTCTTTTCAGTCCACGTCTTTCAGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTTTCGGCGAGTTCTTCGAGCGTGACCCGATCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCGTTTTGGTCTTCGGCGAGTGCCCATAACGTGTTGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTGTTTGGTGCCGCTTCGTTCTTACAAGTCTTCTTTGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGCTGAACCTCCTCTAACCTTTCTCACATCGAGGATAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CCCCTTCTCGCTCGGAAGGGCATCATGCCCAGACTAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCGATGGCCCGTGATGACATCGACATGCCGGGCCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GAGCACGGGGCGCTGCCTATGGTCGGCTGGAACGTA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGCAATCTGGTCGAACTGTCCCCAGTCTCCCAGGTTGC
GTCTCTCCCCAGATACATCTGGGCCGAATTGAAGCG	ATGGCCCGTGATGACATCGACATGCCGGGCCGCACTCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	GTACCCACGGTCGTCTAGCTCTTTGTCAATGCTACG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCT	CCAACTCCTTCTGCTGTTTCTCTATCTCCTTCTTGCGCTG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCT	GGCCCCGCCGAAGCCCATCAGGTGAAACATTCGTCTG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCG	GTTCCTCCACCATCACCCTCATTCAAGACGGATGGGCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCG	ACTATATAGGATGGGAAGTGGTTGATAGTGGGGGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	AGCCATTCCTCATAATCGACATCTGCTCGGCATGCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCT	TGAGCCATTCCTTACAACTCTCTTCAATTAGTTCGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCT	TCCTACCGTAGAGCTAAGCACATACACAGGGACAGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCG	GCTTGTTGCGCTTCCGCGGACTTCTTGTTGCCTTCCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	AATCACCAGCCGCTTCGTCGTACAGAACCTTGTCTTG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCT	TCATTATCACGTCGTTCTCTGCTGTGAGATGTAAG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	TGCTGGCCGAGCTGATCGCGGGGCAGTCGATCATCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCT	CCGACTGTGGTTCCGAAAGTGGCAAGCGCGTGGTCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCT	GCTGGCGGTGGCTTCCCGACGTGTCAGGGCGCGGACCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	CTCTGGCGGGTTCGGGTTCGGCCATCTCTAGACAGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCT	CGTACTGGAACCCGGTGACAACCCTCTGGTCCATG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCA	GCTCCCCGCCCATCACGTTCATAACGGTCAGGTCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	ACCGCCTGCGTCCGGACCGGCCCGAAGTCCAGGCATG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCG	TGGTCGTCTCCGGTGCGCGAATCCAGCACACCCAGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	CGGACCACGGTGCGCTGGAACGAGAACGACCGCTGGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCT	TGATCCTCTGCCGCTGAACGTCCGCGCTTACCTCCAGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	TCGGCTCCGAGTCTGAGGTGCAACAGCAGGGCGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCA	TGTACCCGAGATTGCGCAGCCGAGCGACTGCTTGAGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCA	ACTCGCACCCGTAAGCTCTCCTCCCTAACTTCAGTGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCG	GGGACGTGAACGGGGCCGCGGCGCCCGGCGCGACGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCG	CCGAGGCTATACGCGACCTGAAGACGCGACGGGAATACCTGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCA	GCAGTTCGTCGCGGAACGCCTGTTCCTCGCGCGAACTGG
TCTCTCCCCAGACACATCTGGGGCCGAATTGAAGCG	TTGCAACCATCTCCGGCTTGTACGGGTTGCGACCAG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	TTGGCGGCCTGGTCGCGCTCCAGCTGGGCGAGTTGCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCG	GGTTGTCCGGGGTGACCAGGAGCACGACGTCGTTCCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	GCGTCGGCGCGCTGGAACAGCACGAAGTCGAGTACG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCA	ACGTCCTCGCGCCGCAGGACCGAGGGGCCGAG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	GAAGCCCGCTCCGCTGCCACTCCCAGTTTGTCCAG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCA	CGGGCACCTGCTCCTCGTACCCGGCCAGTGCGACCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	GAAAGGGGCCAGCGCGTGTTCTCGCCACCACCGGCAG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	TCGTTAGGGGGCGCAGTTCGTGATCGCCACGTCGACTCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCA	CCTGCTCGGTGAGGTGCGGCCAATCAAGGTCCACAAGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	GCGCCTGGATGCGCCCCAAACTGCGGCCGCGCTCGCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCT	CTAAGCGATAGGAGACGCAAGGTGGCCAAAAAGAAG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCG	CTGGGGACTGACGAAGACGGAACCGGCGCTTGACCGATTCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	ACTTGATGGGCTTCGGCGGGGCCAAAACAGACAGTAG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	TAATGCCGCGGGCGCGGTTGTGCCGGATCGTGCTCGCCATG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGCAAGTGCCTTTTGCGCGTCCGGGTGGCGCGCCCCCATACCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCAGGTCGGGGGACCACTCGGAGACCTGTGCGAGCGCCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCGCTTTCCTTGCTTCTGCTGCCGTTGCTGCTTGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCCTCAACGTCGTCCTTGTCGCTGGCGAGCACGGTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGGCCCCCGCGGTGATCGACGGGATTGACGTCGGTA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGGTCCCGCCAGCCCTCGATCGCCGTCGAGACGACC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACGAAAAACGGGAACTTGTAATCCGCCCCGAATTCG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ATCGCATCGGAGATCCGGCACACGGCCGACCAGTTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTAGCGCACAAGGTTTCTCCGTAAGGGTCACTCGGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTGGCAGTTCCGTCGAAGAACATCACGTCGACGGAGGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CAGCAAATGGGGCAACCGTCAGCGGGAATGATCGTCGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACGACCTCGCGGCACCTCGTGATCGGGCAGCACACCGGAGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGAGCTCGAACGCGGTGTCGAGGACCGAGGCCCCGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCCTGGGCGCACTGTCTCGGGTGTGCGGGTTGTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGGTCCGGTTCCCGTTCGCGCAACCTCTGGGCTCGTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCAGGATGCACACGCACATCCGCTTCCACGTCGGGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACTTCGTCCTGAATCTGAATCAGGCGAGCCAGCCCTT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGGTTAACTCGCGTGTGCCCCAGCCGCCGGCAGTCGGGCC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AAGGCGTACAACCGGCCTCTCAACACCGCGGGCCTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCACGAGGTGCGACCGGTCCGCGAACGACAGCGCG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AATCGTAAGAGCAAAGCGTTTGAACTGAGTAATCTGCAC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCTTCCGGCCGCGCCGCTGGCACCGGTCCGCCACCGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CAGTCGGGGGGCTTCCGGGTGGTCGCTCCCGTAACTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTCGCGGGCATTACTTTCCCTTGTGTTTGAGTTACCGCC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCCCCCGGCGGCGCGCATCATCGGGCTATGGCAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AATGAGACACGTCCCAATGACATACATCAAGGACCG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGCACGGGCGGGGCCGACGTGACGACGCTCGGCGCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGT	CTCCCACTAATCACCGTTGTGCCCGCAAACGCCGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGT	CCACCGGCGCTCGCACACGTTGACCTTTGTCCCGCCCTCG


>NZ_CP011271|10|10|3903615-3912171|CRISPRCasFinder
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGCAACCATCTGGGCGATTTGTGCGTGTGGATGTCTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCCGCCACCCGCAGCGCGAGCATGATGCGCTGAATG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AGTGGTACCGACATCCAGAGTGGCATTCAGTTGCG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCGGACGCCACGGACAAATCGCTCATCTTCCCGAGCGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GAGCATGTGCATTTCTAACTGTTGCCGCGGACTGAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGCCTTCTTCCGGTCGAGCGCGGCGAGTTTCTCCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGTATCAACGCTCGATTCGCACCCCAGTATCCAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCCGTGGCGTCCACGTTAACGTGCCCGCGCATGGTCGCA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACGTCTATCCGTCTGCAAGACCCCACAAACTGAACGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCGCGTGTTTGATGAACCCGGTGAACGGCACCGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ATAAGCAGCATTGATGTAGTCTCTGTTCAAATTTTTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCTCCTAGACCTGCTAGGGTCTATATTGCAAAAGATG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGGGTACTCGATGTGGTCCGCGAGCGCCTCGGACCCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AGGTGCGAACGGTATTTTGGGAGCGGCGAGAAGACAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AGCTTCGACCTTGGAACCGGTCGCGAGGTGAACGAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACCGGGAAAGGCTGCTCGCCGCACTCATTACCCTCGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CCGAGTTCAACTCTCGGCCCTGGTGCTGCAATCAC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCTACTCAGCGTTCCCCAAACGGGGCTAGGCGCGGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTACACGGTGCCGCACAAGATCCGGCTCGCGACGCGGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CAGATCGGGTTGTAGTGGACATAACATCTGAATCGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGGTGCACCGAGTGAGGATCGGCTCCCGTTTAGTTT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TAAATGGAACTGGATGAATTCTAACTCTTGATCCAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ATCTACTTTAATTTTTTCTTCTTTTCGAAAAACATCAGCAAC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTTGGGGGGAACTGACTAACAGAGTAAAAGTAAAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTCGCGGGCATCGGCGTGGGTGCCGTCGGTTCGTT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTAACCTTCCCCACAAGCGGATAAAGAGAATAAAGGTA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGTCCTACCATGTTTGACGGTTCCTATTTACATTGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CCCGCCAAAGAAGGGCAGGGCGTTAAGGTTGGCGGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CCCGTCGCGGTTCTCGCTCTCCGTTACCTCGCCGTCCTCAC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CATGTCGCGGTGCGTGAAGTGGTAAACGTGGGTCTTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GACCCGGCAGTCCCACCACGTCCCGTACGGCGGCATCCAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTCGGGATCTTCTCCTCGGACGACGGCCGGGGCCGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGATCTCGGACGGGTACACCGCGACGAAGACGGTGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCGCCGACCGAGGACCAGTCGAAGGAGCTGCTCGGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ATGGTCTTGTAGGTCTGTTCCAGTTCGGCCGGCTTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGCGCGACTTTCGAGAATCTCGGCACGCCCCTCAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTTCCGGCCAGTTCTTTTCAGTCCACGTCTTTCAGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTTTCGGCGAGTTCTTCGAGCGTGACCCGATCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCGTTTTGGTCTTCGGCGAGTGCCCATAACGTGTTGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTGTTTGGTGCCGCTTCGTTCTTACAAGTCTTCTTTGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGCTGAACCTCCTCTAACCTTTCTCACATCGAGGATAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CCCCTTCTCGCTCGGAAGGGCATCATGCCCAGACTAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCGATGGCCCGTGATGACATCGACATGCCGGGCCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GAGCACGGGGCGCTGCCTATGGTCGGCTGGAACGTA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGCAATCTGGTCGAACTGTCCCCAGTCTCCCAGGTTGC
GTCTCTCCCCAGATACATCTGGGCCGAATTGAAGCG	ATGGCCCGTGATGACATCGACATGCCGGGCCGCACTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGTACCCACGGTCGTCTAGCTCTTTGTCAATGCTAC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCCAACTCCTTCTGCTGTTTCTCTATCTCCTTCTTGCGCT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGGCCCCGCCGAAGCCCATCAGGTGAAACATTCGTCT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGTTCCTCCACCATCACCCTCATTCAAGACGGATGGGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GACTATATAGGATGGGAAGTGGTTGATAGTGGGGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CAGCCATTCCTCATAATCGACATCTGCTCGGCATGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTGAGCCATTCCTTACAACTCTCTTCAATTAGTTCG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCCTACCGTAGAGCTAAGCACATACACAGGGACAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGCTTGTTGCGCTTCCGCGGACTTCTTGTTGCCTTCC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CAATCACCAGCCGCTTCGTCGTACAGAACCTTGTCTT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCATTATCACGTCGTTCTCTGCTGTGAGATGTAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTGCTGGCCGAGCTGATCGCGGGGCAGTCGATCATC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCCGACTGTGGTTCCGAAAGTGGCAAGCGCGTGGTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGCTGGCGGTGGCTTCCCGACGTGTCAGGGCGCGGACC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CCTCTGGCGGGTTCGGGTTCGGCCATCTCTAGACAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCGTACTGGAACCCGGTGACAACCCTCTGGTCCAT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AGCTCCCCGCCCATCACGTTCATAACGGTCAGGTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CACCGCCTGCGTCCGGACCGGCCCGAAGTCCAGGCAT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTGGTCGTCTCCGGTGCGCGAATCCAGCACACCCAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CCGGACCACGGTGCGCTGGAACGAGAACGACCGCTGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTGATCCTCTGCCGCTGAACGTCCGCGCTTACCTCCAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTCGGCTCCGAGTCTGAGGTGCAACAGCAGGGCG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ATGTACCCGAGATTGCGCAGCCGAGCGACTGCTTGAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AACTCGCACCCGTAAGCTCTCCTCCCTAACTTCAGTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGGGACGTGAACGGGGCCGCGGCGCCCGGCGCGACG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCCGAGGCTATACGCGACCTGAAGACGCGACGGGAATACCTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AGCAGTTCGTCGCGGAACGCCTGTTCCTCGCGCGAACTG
GTCTCTCCCCAGACACATCTGGGGCCGAATTGAAGC	GTTGCAACCATCTCCGGCTTGTACGGGTTGCGACCA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTTGGCGGCCTGGTCGCGCTCCAGCTGGGCGAGTTGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGGTTGTCCGGGGTGACCAGGAGCACGACGTCGTTCC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGCGTCGGCGCGCTGGAACAGCACGAAGTCGAGTAC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AACGTCCTCGCGCCGCAGGACCGAGGGGCCGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGAAGCCCGCTCCGCTGCCACTCCCAGTTTGTCCA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACGGGCACCTGCTCCTCGTACCCGGCCAGTGCGACC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGAAAGGGGCCAGCGCGTGTTCTCGCCACCACCGGCA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTCGTTAGGGGGCGCAGTTCGTGATCGCCACGTCGACTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACCTGCTCGGTGAGGTGCGGCCAATCAAGGTCCACAAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGCGCCTGGATGCGCCCCAAACTGCGGCCGCGCTCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCTAAGCGATAGGAGACGCAAGGTGGCCAAAAAGAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCTGGGGACTGACGAAGACGGAACCGGCGCTTGACCGATTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CACTTGATGGGCTTCGGCGGGGCCAAAACAGACAGTA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTAATGCCGCGGGCGCGGTTGTGCCGGATCGTGCTCGCCAT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCAAGTGCCTTTTGCGCGTCCGGGTGGCGCGCCCCCATACC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AGGTCGGGGGACCACTCGGAGACCTGTGCGAGCGCC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCGCTTTCCTTGCTTCTGCTGCCGTTGCTGCTTGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCCTCAACGTCGTCCTTGTCGCTGGCGAGCACGGTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGGCCCCCGCGGTGATCGACGGGATTGACGTCGGTA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGGTCCCGCCAGCCCTCGATCGCCGTCGAGACGACC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACGAAAAACGGGAACTTGTAATCCGCCCCGAATTCG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ATCGCATCGGAGATCCGGCACACGGCCGACCAGTTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTAGCGCACAAGGTTTCTCCGTAAGGGTCACTCGGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTGGCAGTTCCGTCGAAGAACATCACGTCGACGGAGGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CAGCAAATGGGGCAACCGTCAGCGGGAATGATCGTCGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACGACCTCGCGGCACCTCGTGATCGGGCAGCACACCGGAGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGAGCTCGAACGCGGTGTCGAGGACCGAGGCCCCGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCCTGGGCGCACTGTCTCGGGTGTGCGGGTTGTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGGTCCGGTTCCCGTTCGCGCAACCTCTGGGCTCGTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCAGGATGCACACGCACATCCGCTTCCACGTCGGGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACTTCGTCCTGAATCTGAATCAGGCGAGCCAGCCCTT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGGTTAACTCGCGTGTGCCCCAGCCGCCGGCAGTCGGGCC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AAGGCGTACAACCGGCCTCTCAACACCGCGGGCCTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCACGAGGTGCGACCGGTCCGCGAACGACAGCGCG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AATCGTAAGAGCAAAGCGTTTGAACTGAGTAATCTGCAC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCTTCCGGCCGCGCCGCTGGCACCGGTCCGCCACCGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CAGTCGGGGGGCTTCCGGGTGGTCGCTCCCGTAACTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTCGCGGGCATTACTTTCCCTTGTGTTTGAGTTACCGCC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCCCCCGGCGGCGCGCATCATCGGGCTATGGCAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AATGAGACACGTCCCAATGACATACATCAAGGACCG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGCACGGGCGGGGCCGACGTGACGACGCTCGGCGCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGT	CTCCCACTAATCACCGTTGTGCCCGCAAACGCCGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGT	CCACCGGCGCTCGCACACGTTGACCTTTGTCCCGCCCTCG
GTCTCTCCCCAGATGCTTCTGGGGCCGAATTGAAGC

>NZ_CP011271|10|1|3903615-3912171|CRT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGCAACCATCTGGGCGATTTGTGCGTGTGGATGTCTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCCGCCACCCGCAGCGCGAGCATGATGCGCTGAATG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AGTGGTACCGACATCCAGAGTGGCATTCAGTTGCG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCGGACGCCACGGACAAATCGCTCATCTTCCCGAGCGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GAGCATGTGCATTTCTAACTGTTGCCGCGGACTGAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGCCTTCTTCCGGTCGAGCGCGGCGAGTTTCTCCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGTATCAACGCTCGATTCGCACCCCAGTATCCAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCCGTGGCGTCCACGTTAACGTGCCCGCGCATGGTCGCA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACGTCTATCCGTCTGCAAGACCCCACAAACTGAACGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCGCGTGTTTGATGAACCCGGTGAACGGCACCGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ATAAGCAGCATTGATGTAGTCTCTGTTCAAATTTTTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCTCCTAGACCTGCTAGGGTCTATATTGCAAAAGATG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGGGTACTCGATGTGGTCCGCGAGCGCCTCGGACCCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AGGTGCGAACGGTATTTTGGGAGCGGCGAGAAGACAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AGCTTCGACCTTGGAACCGGTCGCGAGGTGAACGAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACCGGGAAAGGCTGCTCGCCGCACTCATTACCCTCGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CCGAGTTCAACTCTCGGCCCTGGTGCTGCAATCAC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCTACTCAGCGTTCCCCAAACGGGGCTAGGCGCGGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTACACGGTGCCGCACAAGATCCGGCTCGCGACGCGGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CAGATCGGGTTGTAGTGGACATAACATCTGAATCGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGGTGCACCGAGTGAGGATCGGCTCCCGTTTAGTTT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TAAATGGAACTGGATGAATTCTAACTCTTGATCCAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ATCTACTTTAATTTTTTCTTCTTTTCGAAAAACATCAGCAAC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTTGGGGGGAACTGACTAACAGAGTAAAAGTAAAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTCGCGGGCATCGGCGTGGGTGCCGTCGGTTCGTT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTAACCTTCCCCACAAGCGGATAAAGAGAATAAAGGTA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGTCCTACCATGTTTGACGGTTCCTATTTACATTGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CCCGCCAAAGAAGGGCAGGGCGTTAAGGTTGGCGGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CCCGTCGCGGTTCTCGCTCTCCGTTACCTCGCCGTCCTCAC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CATGTCGCGGTGCGTGAAGTGGTAAACGTGGGTCTTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GACCCGGCAGTCCCACCACGTCCCGTACGGCGGCATCCAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTCGGGATCTTCTCCTCGGACGACGGCCGGGGCCGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGATCTCGGACGGGTACACCGCGACGAAGACGGTGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCGCCGACCGAGGACCAGTCGAAGGAGCTGCTCGGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ATGGTCTTGTAGGTCTGTTCCAGTTCGGCCGGCTTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGCGCGACTTTCGAGAATCTCGGCACGCCCCTCAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTTCCGGCCAGTTCTTTTCAGTCCACGTCTTTCAGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTTTCGGCGAGTTCTTCGAGCGTGACCCGATCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCGTTTTGGTCTTCGGCGAGTGCCCATAACGTGTTGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTGTTTGGTGCCGCTTCGTTCTTACAAGTCTTCTTTGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGCTGAACCTCCTCTAACCTTTCTCACATCGAGGATAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CCCCTTCTCGCTCGGAAGGGCATCATGCCCAGACTAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCGATGGCCCGTGATGACATCGACATGCCGGGCCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GAGCACGGGGCGCTGCCTATGGTCGGCTGGAACGTA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGCAATCTGGTCGAACTGTCCCCAGTCTCCCAGGTTGC
GTCTCTCCCCAGATACATCTGGGCCGAATTGAAGCG	ATGGCCCGTGATGACATCGACATGCCGGGCCGCACTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGTACCCACGGTCGTCTAGCTCTTTGTCAATGCTAC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCCAACTCCTTCTGCTGTTTCTCTATCTCCTTCTTGCGCT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGGCCCCGCCGAAGCCCATCAGGTGAAACATTCGTCT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGTTCCTCCACCATCACCCTCATTCAAGACGGATGGGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GACTATATAGGATGGGAAGTGGTTGATAGTGGGGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CAGCCATTCCTCATAATCGACATCTGCTCGGCATGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTGAGCCATTCCTTACAACTCTCTTCAATTAGTTCG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCCTACCGTAGAGCTAAGCACATACACAGGGACAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGCTTGTTGCGCTTCCGCGGACTTCTTGTTGCCTTCC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CAATCACCAGCCGCTTCGTCGTACAGAACCTTGTCTT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCATTATCACGTCGTTCTCTGCTGTGAGATGTAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTGCTGGCCGAGCTGATCGCGGGGCAGTCGATCATC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCCGACTGTGGTTCCGAAAGTGGCAAGCGCGTGGTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGCTGGCGGTGGCTTCCCGACGTGTCAGGGCGCGGACC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CCTCTGGCGGGTTCGGGTTCGGCCATCTCTAGACAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCGTACTGGAACCCGGTGACAACCCTCTGGTCCAT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AGCTCCCCGCCCATCACGTTCATAACGGTCAGGTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CACCGCCTGCGTCCGGACCGGCCCGAAGTCCAGGCAT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTGGTCGTCTCCGGTGCGCGAATCCAGCACACCCAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CCGGACCACGGTGCGCTGGAACGAGAACGACCGCTGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTGATCCTCTGCCGCTGAACGTCCGCGCTTACCTCCAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTCGGCTCCGAGTCTGAGGTGCAACAGCAGGGCG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ATGTACCCGAGATTGCGCAGCCGAGCGACTGCTTGAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AACTCGCACCCGTAAGCTCTCCTCCCTAACTTCAGTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGGGACGTGAACGGGGCCGCGGCGCCCGGCGCGACG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCCGAGGCTATACGCGACCTGAAGACGCGACGGGAATACCTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AGCAGTTCGTCGCGGAACGCCTGTTCCTCGCGCGAACTG
GTCTCTCCCCAGACACATCTGGGGCCGAATTGAAGC	GTTGCAACCATCTCCGGCTTGTACGGGTTGCGACCA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTTGGCGGCCTGGTCGCGCTCCAGCTGGGCGAGTTGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGGTTGTCCGGGGTGACCAGGAGCACGACGTCGTTCC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGCGTCGGCGCGCTGGAACAGCACGAAGTCGAGTAC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AACGTCCTCGCGCCGCAGGACCGAGGGGCCGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGAAGCCCGCTCCGCTGCCACTCCCAGTTTGTCCA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACGGGCACCTGCTCCTCGTACCCGGCCAGTGCGACC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGAAAGGGGCCAGCGCGTGTTCTCGCCACCACCGGCA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTCGTTAGGGGGCGCAGTTCGTGATCGCCACGTCGACTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACCTGCTCGGTGAGGTGCGGCCAATCAAGGTCCACAAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGCGCCTGGATGCGCCCCAAACTGCGGCCGCGCTCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCTAAGCGATAGGAGACGCAAGGTGGCCAAAAAGAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCTGGGGACTGACGAAGACGGAACCGGCGCTTGACCGATTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CACTTGATGGGCTTCGGCGGGGCCAAAACAGACAGTA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTAATGCCGCGGGCGCGGTTGTGCCGGATCGTGCTCGCCAT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCAAGTGCCTTTTGCGCGTCCGGGTGGCGCGCCCCCATACC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AGGTCGGGGGACCACTCGGAGACCTGTGCGAGCGCC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCGCTTTCCTTGCTTCTGCTGCCGTTGCTGCTTGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCCTCAACGTCGTCCTTGTCGCTGGCGAGCACGGTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGGCCCCCGCGGTGATCGACGGGATTGACGTCGGTA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGGTCCCGCCAGCCCTCGATCGCCGTCGAGACGACC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACGAAAAACGGGAACTTGTAATCCGCCCCGAATTCG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ATCGCATCGGAGATCCGGCACACGGCCGACCAGTTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTAGCGCACAAGGTTTCTCCGTAAGGGTCACTCGGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTGGCAGTTCCGTCGAAGAACATCACGTCGACGGAGGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CAGCAAATGGGGCAACCGTCAGCGGGAATGATCGTCGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACGACCTCGCGGCACCTCGTGATCGGGCAGCACACCGGAGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGAGCTCGAACGCGGTGTCGAGGACCGAGGCCCCGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCCTGGGCGCACTGTCTCGGGTGTGCGGGTTGTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGGTCCGGTTCCCGTTCGCGCAACCTCTGGGCTCGTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCAGGATGCACACGCACATCCGCTTCCACGTCGGGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACTTCGTCCTGAATCTGAATCAGGCGAGCCAGCCCTT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGGTTAACTCGCGTGTGCCCCAGCCGCCGGCAGTCGGGCC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AAGGCGTACAACCGGCCTCTCAACACCGCGGGCCTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCACGAGGTGCGACCGGTCCGCGAACGACAGCGCG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AATCGTAAGAGCAAAGCGTTTGAACTGAGTAATCTGCAC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCTTCCGGCCGCGCCGCTGGCACCGGTCCGCCACCGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CAGTCGGGGGGCTTCCGGGTGGTCGCTCCCGTAACTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTCGCGGGCATTACTTTCCCTTGTGTTTGAGTTACCGCC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCCCCCGGCGGCGCGCATCATCGGGCTATGGCAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AATGAGACACGTCCCAATGACATACATCAAGGACCG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGCACGGGCGGGGCCGACGTGACGACGCTCGGCGCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGT	CTCCCACTAATCACCGTTGTGCCCGCAAACGCCGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGT	CCACCGGCGCTCGCACACGTTGACCTTTGTCCCGCCCTCG
GTCTCTCCCCAGATGCTTCTGGGGCCGAATTGAAGC

>NZ_CP011271|10|3|3910167-3912171|PILER-CR
	CGCAACCATCTGGGCGATTTGTGCGTGTGGATGTCTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCCGCCACCCGCAGCGCGAGCATGATGCGCTGAATG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AGTGGTACCGACATCCAGAGTGGCATTCAGTTGCG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCGGACGCCACGGACAAATCGCTCATCTTCCCGAGCGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GAGCATGTGCATTTCTAACTGTTGCCGCGGACTGAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGCCTTCTTCCGGTCGAGCGCGGCGAGTTTCTCCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGTATCAACGCTCGATTCGCACCCCAGTATCCAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCCGTGGCGTCCACGTTAACGTGCCCGCGCATGGTCGCA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACGTCTATCCGTCTGCAAGACCCCACAAACTGAACGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCGCGTGTTTGATGAACCCGGTGAACGGCACCGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ATAAGCAGCATTGATGTAGTCTCTGTTCAAATTTTTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCTCCTAGACCTGCTAGGGTCTATATTGCAAAAGATG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGGGTACTCGATGTGGTCCGCGAGCGCCTCGGACCCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AGGTGCGAACGGTATTTTGGGAGCGGCGAGAAGACAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AGCTTCGACCTTGGAACCGGTCGCGAGGTGAACGAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACCGGGAAAGGCTGCTCGCCGCACTCATTACCCTCGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CCGAGTTCAACTCTCGGCCCTGGTGCTGCAATCAC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCTACTCAGCGTTCCCCAAACGGGGCTAGGCGCGGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTACACGGTGCCGCACAAGATCCGGCTCGCGACGCGGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CAGATCGGGTTGTAGTGGACATAACATCTGAATCGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGGTGCACCGAGTGAGGATCGGCTCCCGTTTAGTTT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TAAATGGAACTGGATGAATTCTAACTCTTGATCCAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ATCTACTTTAATTTTTTCTTCTTTTCGAAAAACATCAGCAAC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTTGGGGGGAACTGACTAACAGAGTAAAAGTAAAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTCGCGGGCATCGGCGTGGGTGCCGTCGGTTCGTT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTAACCTTCCCCACAAGCGGATAAAGAGAATAAAGGTA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGTCCTACCATGTTTGACGGTTCCTATTTACATTGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CCCGCCAAAGAAGGGCAGGGCGTTAAGGTTGGCGGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CCCGTCGCGGTTCTCGCTCTCCGTTACCTCGCCGTCCTCAC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CATGTCGCGGTGCGTGAAGTGGTAAACGTGGGTCTTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GACCCGGCAGTCCCACCACGTCCCGTACGGCGGCATCCAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTCGGGATCTTCTCCTCGGACGACGGCCGGGGCCGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGATCTCGGACGGGTACACCGCGACGAAGACGGTGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCGCCGACCGAGGACCAGTCGAAGGAGCTGCTCGGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ATGGTCTTGTAGGTCTGTTCCAGTTCGGCCGGCTTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGCGCGACTTTCGAGAATCTCGGCACGCCCCTCAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTTCCGGCCAGTTCTTTTCAGTCCACGTCTTTCAGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTTTCGGCGAGTTCTTCGAGCGTGACCCGATCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCGTTTTGGTCTTCGGCGAGTGCCCATAACGTGTTGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CTGTTTGGTGCCGCTTCGTTCTTACAAGTCTTCTTTGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGCTGAACCTCCTCTAACCTTTCTCACATCGAGGATAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CCCCTTCTCGCTCGGAAGGGCATCATGCCCAGACTAG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCGATGGCCCGTGATGACATCGACATGCCGGGCCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GAGCACGGGGCGCTGCCTATGGTCGGCTGGAACGTA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGCAATCTGGTCGAACTGTCCCCAGTCTCCCAGGTTGC
GTCTCTCCCCAGATACATCTGGGCCGAATTGAAGCG	ATGGCCCGTGATGACATCGACATGCCGGGCCGCACTCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	GTACCCACGGTCGTCTAGCTCTTTGTCAATGCTACG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCT	CCAACTCCTTCTGCTGTTTCTCTATCTCCTTCTTGCGCTG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCT	GGCCCCGCCGAAGCCCATCAGGTGAAACATTCGTCTG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCG	GTTCCTCCACCATCACCCTCATTCAAGACGGATGGGCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCG	ACTATATAGGATGGGAAGTGGTTGATAGTGGGGGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	AGCCATTCCTCATAATCGACATCTGCTCGGCATGCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCT	TGAGCCATTCCTTACAACTCTCTTCAATTAGTTCGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCT	TCCTACCGTAGAGCTAAGCACATACACAGGGACAGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCG	GCTTGTTGCGCTTCCGCGGACTTCTTGTTGCCTTCCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	AATCACCAGCCGCTTCGTCGTACAGAACCTTGTCTTG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCT	TCATTATCACGTCGTTCTCTGCTGTGAGATGTAAG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	TGCTGGCCGAGCTGATCGCGGGGCAGTCGATCATCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCT	CCGACTGTGGTTCCGAAAGTGGCAAGCGCGTGGTCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCT	GCTGGCGGTGGCTTCCCGACGTGTCAGGGCGCGGACCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	CTCTGGCGGGTTCGGGTTCGGCCATCTCTAGACAGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCT	CGTACTGGAACCCGGTGACAACCCTCTGGTCCATG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCA	GCTCCCCGCCCATCACGTTCATAACGGTCAGGTCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	ACCGCCTGCGTCCGGACCGGCCCGAAGTCCAGGCATG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCG	TGGTCGTCTCCGGTGCGCGAATCCAGCACACCCAGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	CGGACCACGGTGCGCTGGAACGAGAACGACCGCTGGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCT	TGATCCTCTGCCGCTGAACGTCCGCGCTTACCTCCAGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	TCGGCTCCGAGTCTGAGGTGCAACAGCAGGGCGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCA	TGTACCCGAGATTGCGCAGCCGAGCGACTGCTTGAGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCA	ACTCGCACCCGTAAGCTCTCCTCCCTAACTTCAGTGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCG	GGGACGTGAACGGGGCCGCGGCGCCCGGCGCGACGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCG	CCGAGGCTATACGCGACCTGAAGACGCGACGGGAATACCTGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCA	GCAGTTCGTCGCGGAACGCCTGTTCCTCGCGCGAACTGG
TCTCTCCCCAGACACATCTGGGGCCGAATTGAAGCG	TTGCAACCATCTCCGGCTTGTACGGGTTGCGACCAG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	TTGGCGGCCTGGTCGCGCTCCAGCTGGGCGAGTTGCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCG	GGTTGTCCGGGGTGACCAGGAGCACGACGTCGTTCCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	GCGTCGGCGCGCTGGAACAGCACGAAGTCGAGTACG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCA	ACGTCCTCGCGCCGCAGGACCGAGGGGCCGAG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	GAAGCCCGCTCCGCTGCCACTCCCAGTTTGTCCAG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCA	CGGGCACCTGCTCCTCGTACCCGGCCAGTGCGACCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	GAAAGGGGCCAGCGCGTGTTCTCGCCACCACCGGCAG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	TCGTTAGGGGGCGCAGTTCGTGATCGCCACGTCGACTCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCA	CCTGCTCGGTGAGGTGCGGCCAATCAAGGTCCACAAGG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	GCGCCTGGATGCGCCCCAAACTGCGGCCGCGCTCGCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCT	CTAAGCGATAGGAGACGCAAGGTGGCCAAAAAGAAG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCG	CTGGGGACTGACGAAGACGGAACCGGCGCTTGACCGATTCG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	ACTTGATGGGCTTCGGCGGGGCCAAAACAGACAGTAG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCC	TAATGCCGCGGGCGCGGTTGTGCCGGATCGTGCTCGCCATG
TCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCGCAAGTGCCTTTTGCGCGTCCGGGTGGCGCGCCCCCATACCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGCAGGTCGGGGGACCACTCGGAGACCTGTGCGAGCGCCGTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TCGCTTTCCTTGCTTCTGCTGCCGTTGCTGCTTGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCCTCAACGTCGTCCTTGTCGCTGGCGAGCACGGTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGGCCCCCGCGGTGATCGACGGGATTGACGTCGGTA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGGTCCCGCCAGCCCTCGATCGCCGTCGAGACGACC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACGAAAAACGGGAACTTGTAATCCGCCCCGAATTCG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ATCGCATCGGAGATCCGGCACACGGCCGACCAGTTC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTAGCGCACAAGGTTTCTCCGTAAGGGTCACTCGGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTGGCAGTTCCGTCGAAGAACATCACGTCGACGGAGGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CAGCAAATGGGGCAACCGTCAGCGGGAATGATCGTCGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACGACCTCGCGGCACCTCGTGATCGGGCAGCACACCGGAGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGAGCTCGAACGCGGTGTCGAGGACCGAGGCCCCGG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCCTGGGCGCACTGTCTCGGGTGTGCGGGTTGTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TGGTCCGGTTCCCGTTCGCGCAACCTCTGGGCTCGTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCAGGATGCACACGCACATCCGCTTCCACGTCGGGA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	ACTTCGTCCTGAATCTGAATCAGGCGAGCCAGCCCTT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GGGTTAACTCGCGTGTGCCCCAGCCGCCGGCAGTCGGGCC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AAGGCGTACAACCGGCCTCTCAACACCGCGGGCCTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCACGAGGTGCGACCGGTCCGCGAACGACAGCGCG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AATCGTAAGAGCAAAGCGTTTGAACTGAGTAATCTGCAC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GCTTCCGGCCGCGCCGCTGGCACCGGTCCGCCACCGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CAGTCGGGGGGCTTCCGGGTGGTCGCTCCCGTAACTG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	GTCGCGGGCATTACTTTCCCTTGTGTTTGAGTTACCGCC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	TTCCCCCGGCGGCGCGCATCATCGGGCTATGGCAA
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	AATGAGACACGTCCCAATGACATACATCAAGGACCG
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGC	CGCACGGGCGGGGCCGACGTGACGACGCTCGGCGCGC
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGT	CTCCCACTAATCACCGTTGTGCCCGCAAACGCCGT
GTCTCTCCCCAGATACATCTGGGGCCGAATTGAAGT	CCACCGGCGCTCGCACACGTTGACCTTTGTCCCGCCCTCG
GTCTCTCCCCAGATGCTTCTGGGGCCGAATTGAAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_082840266.1\|3892063_3892423_-\|DUF5615-family-PIN-like-protein	unknown	unknown	gnl\|CDD\|375906
NZ_CP011271.1\|WP_082838128.1\|3918818_3920156_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379252
NZ_CP011271.1\|WP_082839639.1\|3912452_3913817_-\|transposase	unknown	unknown	unknown
NZ_CP011271.1\|WP_082840270.1\|3895421_3897680_+\|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09696_cas3_CAS-I-U	gnl\|CDD\|187827
NZ_CP011271.1\|WP_162271725.1\|3916381_3916888_-\|transposase	unknown	unknown	gnl\|CDD\|315923
NZ_CP011271.1\|WP_082838323.1\|3897685_3898972_-\|IS701-family-transposase	unknown	unknown	gnl\|CDD\|379252
NZ_CP011271.1\|WP_082840267.1\|3892419_3892656_-\|DUF433-domain-containing-protein	unknown	unknown	gnl\|CDD\|377269
NZ_CP011271.1\|WP_082843321.1\|3920480_3921269_-\|transposase	unknown	unknown	gnl\|CDD\|372577
NZ_CP011271.1\|WP_162271723.1\|3899891_3900479_+\|hypothetical-protein	cas8u2	cd09765_cas8u2_CAS-I-U	gnl\|CDD\|274984
NZ_CP011271.1\|WP_052555344.1\|3895124_3895409_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP011271.1\|WP_082840268.1\|3892793_3893012_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082840272.1\|3901581_3903237_+\|type-I-U-CRISPR-associated-protein-Cas5/Cas6	cas5u	cd09667_cas5u_CAS-I-U	gnl\|CDD\|187798
NZ_CP011271.1\|WP_157469540.1\|3916932_3917418_-\|ISAs1-family-transposase	unknown	unknown	gnl\|CDD\|227720
NZ_CP011271.1\|WP_082840271.1\|3900471_3901569_+\|type-I-U-CRISPR-associated-protein-Cas7	cas7	cd09678_cas7_CAS-I-U	gnl\|CDD\|187809
NZ_CP011271.1\|WP_052554838.1\|3917414_3918089_-\|ISAs1-family-transposase	unknown	unknown	gnl\|CDD\|379382
NZ_CP011271.1\|WP_082840273.1\|3912209_3912431_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|315923
NZ_CP011271.1\|WP_082840275.1\|3914869_3916111_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|334163
NZ_CP011271.1\|WP_082840269.1\|3893042_3894752_+\|CRISPR-associated-endonuclease-Cas4/Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NZ_CP011271.1\|WP_162271724.1\|3913846_3914212_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|315923
NZ_CP011271.1\|WP_082840278.1\|3918127_3918682_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379282

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_082840266.1\|3892063_3892423_-\|DUF5615-family-PIN-like-protein	gnl\|CDD\|375906	pfam18480, DUF5615, Domain of unknown function (DUF5615). This is a domain of unknown function found in potential toxin-antitoxin system component.	5.08594e-17
NZ_CP011271.1\|WP_082838128.1\|3918818_3920156_+\|hypothetical-protein	gnl\|CDD\|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.24905e-18
NZ_CP011271.1\|WP_082840270.1\|3895421_3897680_+\|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|187827	cd09696, Cas3_I, CRISPR/Cas system-associated protein Cas3; Distinct Cas3 family with HD domain fused to C-termus of Helicase domain. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DNA helicase Cas3; This protein includes both DEAH and HD motifs; signature gene for Type I.	0
NZ_CP011271.1\|WP_162271725.1\|3916381_3916888_-\|transposase	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.75898e-32
NZ_CP011271.1\|WP_082838323.1\|3897685_3898972_-\|IS701-family-transposase	gnl\|CDD\|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.63533e-46
NZ_CP011271.1\|WP_082840267.1\|3892419_3892656_-\|DUF433-domain-containing-protein	gnl\|CDD\|377269	pfam04255, DUF433, Protein of unknown function (DUF433).	1.17148e-21
NZ_CP011271.1\|WP_162271723.1\|3899891_3900479_+\|hypothetical-protein	gnl\|CDD\|274984	TIGR04106, hypothetical_protein_GobsU_11505, CRISPR-associated protein GSU0052/csb3, Dpsyc system. This model describes a CRISPR-associated (cas) protein unique to the Dpsyc subtype (named for Desulfotalea psychrophila), a variant type I-C subtype, although not universal to the that subtype. Members of this family occur in CRISPR loci of Geobacter sulfurreducens PCA, Gemmata obscuriglobus UQM 2246, Rhodospirillum centenum SW, Planctomyces limnophilus DSM 3776, and Methylosinus trichosporium OB3b.	5.79787e-19
NZ_CP011271.1\|WP_052555344.1\|3895124_3895409_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	7.21193e-22
NZ_CP011271.1\|WP_082843321.1\|3920480_3921269_-\|transposase	gnl\|CDD\|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.30383e-22
NZ_CP011271.1\|WP_082840272.1\|3901581_3903237_+\|type-I-U-CRISPR-associated-protein-Cas5/Cas6	gnl\|CDD\|187798	cd09667, Csb2_I-U, CRISPR/Cas system-associated protein Csb2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Duplicated RAMP domains; also known as GSU0054 family.	5.39582e-107
NZ_CP011271.1\|WP_157469540.1\|3916932_3917418_-\|ISAs1-family-transposase	gnl\|CDD\|227720	COG5433, COG5433, Transposase [DNA replication, recombination, and repair].	0.000513124
NZ_CP011271.1\|WP_082840271.1\|3900471_3901569_+\|type-I-U-CRISPR-associated-protein-Cas7	gnl\|CDD\|187809	cd09678, Csb1_I-U, CRISPR/Cas system-associated protein Csb1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; Contains several motifs similar to Cas7 family; also known as GSU0053 family.	3.42467e-59
NZ_CP011271.1\|WP_052554838.1\|3917414_3918089_-\|ISAs1-family-transposase	gnl\|CDD\|379382	pfam13808, DDE_Tnp_1_assoc, DDE_Tnp_1-associated. This domain is frequently found N-terminal to the transposase, IS family DDE_Tnp_1, pfam01609 and its relatives.	1.27678e-16
NZ_CP011271.1\|WP_082840273.1\|3912209_3912431_-\|hypothetical-protein	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.35257e-05
NZ_CP011271.1\|WP_082840275.1\|3914869_3916111_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|334163	pfam00589, Phage_integrase, Phage integrase family. Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase are Arg-173, His-289, Arg-292 and Tyr-324.	1.30067e-11
NZ_CP011271.1\|WP_082840269.1\|3893042_3894752_+\|CRISPR-associated-endonuclease-Cas4/Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	1.00331e-119
NZ_CP011271.1\|WP_162271724.1\|3913846_3914212_-\|hypothetical-protein	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	8.36992e-14
NZ_CP011271.1\|WP_082840278.1\|3918127_3918682_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379282	pfam13592, HTH_33, Winged helix-turn helix. This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.	8.41644e-14

>NZ_CP011271.1|WP_082840272.1|3901581_3903237_+|type-I-U-CRISPR-associated-protein-Cas5/Cas6
MPNYLCVTIRFADPTFRGRGDGGEPEWPPSPLRVFQALVAASAARFGDPSLFRDYAVPAFGWLGGLRPPLVVAPVCATGIPHRLAVPNNDMDVVGRAWARNVEPDVQPAQLKTLKTVRATHIVGDDEFPAVQYLWEIAEADQAECDRHKEVLFAAARSIVALGWGVDMAVGHGQLISDEAAQSLSGERWNPVSAGGERLRIPTEDTFDALVTRHQHFRNRLSADGFKPVPPLTAFDTVGYRRGTEPASRPFVVFELHKTVAKLADLPPGKSRFRPFDPVRTPNFARTGGANDPCGAIVVAGLVRHATATAAREQQWSEDRIASFVLGHGDQKGGQATTDNRLMYLPLPSITPLKVESIRRVLIVGPPGENLDRLRQLLNGRELVPQNEGAGPVAMLVVGSRADKVVDPYVRSAHVWSTVTPVVLPGFDDPDGIRRRLSERDPARALTGDEKQRQLAALNRRTCDLLLKAFAHAGIGPELLSAEKLDRGEAELEWRDVGFHAGVDLARRYSVNTPRYPRYHVRVRFSHPVSGPLAIGAGRYRGMGVFTVGFG
>NZ_CP011271.1|WP_082840271.1|3900471_3901569_+|type-I-U-CRISPR-associated-protein-Cas7
MSNALTKFDSWLDDSGPAALVIREPLVPVEGKDGVLFPATFAAAEDKTKFAGGYNIDTFSDGTNICLVDSVGSQANRIEPIFAKPEYAGLVPQIVIMAGSKAISLLEAGHRAGDAIVRCSTLKNQLQAAFKAVQNGDAEPLAQIAPTSLVFGVWDSRDTQAKLPRLVASTIRAFNVKRLLRSAQFVPATEYVERELLDEPADKKTSDAYAERGFVHVPASGSHGGVIAEKVRRDATLSIAALRLLAVREAGSVMAMDRTRDLRRYILGLALVALTAPQSSYLRQGCNLVPDTDSPREFTLVHADGRREKFDLRHPDAITYAQAAAKAFKVADGLTVEFNKSMAKQDITGEPPTESEASTKKPKRK
>NZ_CP011271.1|WP_162271723.1|3899891_3900479_+|hypothetical-protein
MKTLLAPLQLVFSGHSGALTLDAWMTIRVEKGEVSTGANPPWNFWSGQQTPLRIWTPVRAALAELLPQLDQMKRTALFEQRQFLTGRFGFDPGPAWNALDVGFSPNEQGIAVESSPAVELLAAIGLQRFRPEMGANRDSFIYSTWGISLPPLVARAAACTAIRFDPSAVYRGRVVTRGQYAALGYSTILSGDSDE
>NZ_CP011271.1|WP_082838323.1|3897685_3898972_-|IS701-family-transposase
MTDQEIARLGPAFAHYLGRYRGCFLQKRTADHFDNYGRGLLSELPRKSVEPIALACGTAVRTLQEFLTTADWQHESAREQLQRRCAEVLDGLPGDDLGTVGVIDETSAVKKGDRTPGVQRQYLGCVGKIDNGIVTVHVGVAKGTFQALLDADLYLPESWNADRPRCQAAGIPDEVRYRPKWRIAYEQLVRLDAHGVRFDWLVFDEGYGSKVPFLRALDAVGQPFVGEVPVSFSVTTAARDEPRRADSVLRADDARRGRRFRVSRKTVGDTRWRATSRLIEVRGCRWMLVVAQNESTAEVKYFVTNATDEPLARVLRVAFRRATIEHQFRVAKSEAGMTHYEGRQYVGLVRHLILGLVVLGFVSIHTDRLRGEKTAGDDGAGVPGAERPMCGDVPSEARDAGTTARRRGHPLPPTAERAGHESAQKMAT
>NZ_CP011271.1|WP_082840270.1|3895421_3897680_+|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3
MADINFDAAFEALTGNAPFPWQRALYERFTADRKDNIPESCNLPTGLGKTSVIAVWLIALATHPTKMPRRLVYVVNRRTVVDQTTDEVVKIRKRLPEAPQIQDALWELCAVRPDKPDPENDRPLAISTLRGQFADNREWSADPSRPAVICGTVDMIGSRLLFSGYGCGFRTRPLHAGFLGQDSLIVHDEAHLEPAFQELLIAIKKEQHEGRTPDFRPLKVMELTATSRAGGAEPFGLTDPDYKNGTVQKRIGAKKALHLHENKDEKKLADEIADLALKYKDSGRAILVFVRKVEDVEKIVARLNKEKQHPQQLTGTLRGYERDTLPRDEVFARFLPNSNRPEGVKPAEGTVYLVCTSAGEVGVNISADHLVCDLSTFESMTQRFGRVNRFGDRTDTEIHVIHPKTFAGEDKFASPLKLTLGLLELLNGDASPSALTALRELAIKEGSGAQPPSSDRIQALRDYVNANQGADPRLGGFAPQPLMLPTSDILFDAWALTTVHELPGRPPVAEYLHGVEDEKNRETHVAWREEVNLFSGTGVNELQIAELLDTFPLKPHEMLRDSTWRVQDELSALSGARADLSVWVIDPDDEVRVLELGELAKRDNKKKYIQNLIGCTVVLPPTAGGLTSTGTLDSKADRDSERKYDVAGSVQLASGVPLVRLKVTLREGELVYELVAPVRELGTEFVRLPENVTRWEEARTIRTRCREVGLPPMRVAYRLDLRTSEDDLDGLLEYLVLKPESGKKLALQRGFR
>NZ_CP011271.1|WP_052555344.1|3895124_3895409_+|CRISPR-associated-endonuclease-Cas2
MDSYLVCYDISNPKRLRRVARTCEDFGYRKQLSVFLVRVSATDFVRLRSRLYDIIDLNEDQVLFLPLTETSLQRMEAIGRPTDAYDKNDVVMIL
>NZ_CP011271.1|WP_082840269.1|3893042_3894752_+|CRISPR-associated-endonuclease-Cas4/Cas1
MSATTDPIPVRALNQVTYCPRLYYLQYVDAVMPTNEHVEGGLHDHRRVDAPDLKNKTRTDRGTATSRGIALSSEALGISGILDVIEEKNGEQYPVETKHGPAPHDGDGQPTVWDNDAVQICAQAMLMEEAFGKPVPRGYQFHVGSRERVPLELTPELRQKTRDAVTRCRELAALDAPPDPLPSELRHRCFGCSLAPVCLPEETLYQIGHPAPVKTEEAPPELKRVIPQSDDGAVLYLQEPGSSVGKRSEHLVIKKDGKEMSRVPMHAVRQVVVCGNVQVSTQALETLATNDIPVSYVTGHGRFIGTFSPAPAKNVSLRESQFRKFSDPAACLELSKAVVRAKLANQRALLMRSLRGEEEARGSHEPAARGIYGLLGVIDDQTSVDSVLGIEGQGAALYFGEFGRFLKQPPTGKRFDFTSRNRRPPRDPVNALLSFAYAMLAKDCFAAACTVGFDPYKGFFHQGRHGKPSLALDLMEEFRPVIADSVVLTLINNETLTPDDFITWRDACNLTESGRKAFFAAYEQRKSTIIMHPLYNYKMSYARMLEVQARMLASFVRGSTPTYTGFVVR
>NZ_CP011271.1|WP_082840268.1|3892793_3893012_+|hypothetical-protein
MEPVLVAAYAEMLKARPDECSVDRILEDPQFRGEFLGRVRASAADRTEFDILRTLHNLRKRSKLPRRDAPSA
>NZ_CP011271.1|WP_082840267.1|3892419_3892656_-|DUF433-domain-containing-protein
MATAQIVSDPNILFGKPVIAGTRISVELVLEELGGGLSVDDLLREYPHITREQILAAVRFAAEAIRNDAVYPFGKVPA
>NZ_CP011271.1|WP_082840266.1|3892063_3892423_-|DUF5615-family-PIN-like-protein
MNLVADESLLGAIIDRLRADGHTVRAIRDTNGGAPDTDVLTIAVNEHAVLLTQDKDFGELVFRNRLTHTGIVLIRLTGMSADDRAQLVSEVIRDHANELPTAFTVVSNNGVRIRPVTPP
>NZ_CP011271.1|WP_082840273.1|3912209_3912431_-|hypothetical-protein
MRLPAYAPDLNPVEVVWSWLKWGRLVNFVPDHLTELDDWAVEYLVQLKFDPKLLRALWERSDLPFPTPRIKQP
>NZ_CP011271.1|WP_082839639.1|3912452_3913817_-|transposase
MLLDAVLERFIAHSPMAVAIRGAFEYALDPGHLDDLFVRIAGDRDDRELLFSTCVDLMATVVCRVKPSAHAAYQADDHLPVSVSAVYARLARVPTAAGRERVQHTAERLGPVIRAMGGAEVEPLPGYRVKVLDGNHLSKTQRRLKPLRDVIAGPLPGQALVVLDPALGLAIDVIPCEDAHAQERSLLDPILATVDENDVWVADRNFCTTGFLFGIARRNGSFVIRRHAATLSWDRESDWVEVGRTDTGALAEQTIWLTEPSGAELAVRRVRLTLDHPTRDGDEVIEVLTNLPARAATGARVVELYRGRWSVEGLFLRLTTVLRCEVNALGYPPAALFGFCVALAAGNVYAGVKGALRAAHGAGRADGVSDYHLALEVSGACPGLWIAVPAEAWVEIGVWSVGRMAEWLVGLARGANLGRYRKATRGPKKPRPPRTRFPDAKHVATSRLLNDEQT
>NZ_CP011271.1|WP_162271724.1|3913846_3914212_-|hypothetical-protein
MFLNPTVRRSWSLIGRTPVIGGDGGHRKKMSVIGAVTVSPRAHRLGFYFATAVDGYFCAEKVVAFLRDLLEHLPGKVLVIWDGGGNHKGPVIRAFLARNRRVTLVRHPFQHRRVIRNSLRG
>NZ_CP011271.1|WP_082840275.1|3914869_3916111_+|tyrosine-type-recombinase/integrase
MPRSVPIPSYRLHKPSGQAVVTIRTATGERRDVYLGLYNSPESRAEYGRVVSEVASGAVVAGLVSRPLEPTVDQILLAFWRHAEQHYRRPDGTPTQEISEYRQAFRILQALYGHTLAKDFGPTALKAVRAEMVKKRWARTLVNRRIGRVRRAFKWAASEQLVPVSTHHALGTVGGLQRGRSESPEMEPIQPVEWEHVVATLPFLRPHVAAMIQVQWLTGMRPGEVCSIRPCDIDTSAAVWVYRPPYSKMSYQGRQRVIAIGPRAQAVLRAFAPKNPSDFYFSPVASVERFHAERVANRKTPKYASHMKRNATKRVREGERKPAARYTNKSYGYAIRRAVARANWARIEAAVELEFHIPEWAPNQLRHSHGTAVRHRYDLESAQAVLGHERMSTTEIYAEKNLSLALKVASEMG
>NZ_CP011271.1|WP_162271725.1|3916381_3916888_-|transposase
MADHCSGYGYAKRGERATMDVPDPHIGINMVSSITNEGALRFMTYPGTMTGERFVVFLGRLLRTTTGKIVLIVDRLKAHQSGVVKEWVAAHADRLEVFELPRRAPERNPDEYLNNDVKRAVTEDGLPGSKPALRERLQHVMRTLGHLPKHVVSYFLQPCVLYAAATAT
>NZ_CP011271.1|WP_157469540.1|3916932_3917418_-|ISAs1-family-transposase
MKTCFSAPADRVVTTSEKGHGRIEKRTLESTPILTAGQKWKGLKQGLRITRERTVKGNRTVEVVYGITSLSMERANAATLRAILRDHWQIENGLHYVRDVTLGEDACRVRKGTAPPVLAAVRNVVIHLLADVDAKSRPEALELLQLDPARARNLIGIPQTE
>NZ_CP011271.1|WP_052554838.1|3917414_3918089_-|ISAs1-family-transposase
MPACTLHEAFAALPEPRGTHGLIHPLPAVTGLVVLAMLMGRKSLQGIARFGRQHGAPLAHALGFRRGKTPAASTLSRTLRRFDAPQLEATISQWIRDRIAPRAFEQISIDGKTLRGSRDGDVPGQHLVAAYAPAVEAVLAQVRVGSKTNEHKAALGLLGILPLQGRVVVGDAMFCQRDVAEQVIDRGGEYLLVVKDNQPGLEADIEGGFAFETAARGIAAATSP
>NZ_CP011271.1|WP_082840278.1|3918127_3918682_-|helix-turn-helix-domain-containing-protein
MALTLPDGVLDALRLRALRACERGFTHADVADILGVATETVCRWWVAYSTGGPEAIPHERTGRPPGSGAALSDEHATRIQRLIDTTTPEDQGLTFPLWSRRAIGELIRTDCDVLLAVRTVGEYLRRWGYTAKKPARHAEKQDPEEVRLWLEYTYPALKARARKERAEVHQGHSLFHLVGLGWCR
>NZ_CP011271.1|WP_082838128.1|3918818_3920156_+|hypothetical-protein
MILPPEAHALVQVLALHFTSPTYQRFSVLLVGALVSTGRRTVANLLRTLRHLAPGHPTDYRRVLSRAPWSGLALGCALMRFVLDHIVPDGPVRLVGDDTVDGHKGAHVYGKARHRDPVRSTHSYTAFRYGHKWVVLAVLVKFPFATRPWALPVLIDLYRSADDDRKRNRPHRTPARIMCSLLRLLLIRFPDRTFVFAGDSGYGTHDVARFCHRHRGRLTLVSKLHPDANLFDPPSPYTGKGRPRVKGDRCPKPRQAVAAATTLTRLEVGWYGGGTRTVQALGGTGHWYKAGRGLVPVRGVFVRDTTGTHRDEYFFTTDLDLGPAAAIGHYCGRWNIETTFQERRAELGLETTRGWREKTVVRAAPCLFGLYTVTAILFHARPEAKRTGSVEWPGKTVTTFSDALAAVRRWLWDQALLPQAGDGTTLNKLPDRVRELLLTALAPAA
>NZ_CP011271.1|WP_082843321.1|3920480_3921269_-|transposase
MAELEPRYPQADAKRKKRPSRQRKPGAGRKFARPLSDRLLMLLMYYRTYTTHAFLGFLFGIDDRSVCRNINPLQPLLAGIFRIPERRIEREPDEIRELFFDATERAIPRPTRRQKRFDSGKNKRHTLKHQVVVVRKRKSSGRGGQRRRVRIAAVSKAFPGKTHDKKVYDATAVVRPDGVRRTGDTAYLGTGLCTPRRRPPKGPLTARQKAGNRRVSRRRIVVEHGIGKMKVWRIAAERYRNPRRRHTLIIKNVAGLHNLMYA

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Crispr_ID: NZ_CP011271_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_11

4213049-4213159

Orphan

Consensus_repeat	Method
GCCAAAAACATATGCCCTATACCCCCATCCTTGCGAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_11

>merge|NZ_CP011271|11|4213049-4213159|CRISPRCasFinder
GCCAAAAACATATGCCCTATACCCCCATCCTTGCGACGACGCGAAAGCCGCAGCCGTGGCCGCCGCGACCGTCGGCCAAAAACATATGCCCTATACCCCCATCCTCGCGAC

>NZ_CP011271|11|11|4213049-4213159|CRISPRCasFinder
GCCAAAAACATATGCCCTATACCCCCATCCTTGCGAC	GACGCGAAAGCCGCAGCCGTGGCCGCCGCGACCGTCG
GCCAAAAACATATGCCCTATACCCCCATCCTCGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_082840439.1\|4212658_4212934_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052554034.1\|4223147_4225181_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP011271.1\|WP_082840435.1\|4205037_4206543_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223717
NZ_CP011271.1\|WP_082843335.1\|4197737_4198544_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224041
NZ_CP011271.1\|WP_052554009.1\|4198559_4199693_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227005
NZ_CP011271.1\|WP_157469584.1\|4222586_4223039_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052554028.1\|4217304_4218954_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224196
NZ_CP011271.1\|WP_082843336.1\|4199689_4201468_-\|CRTAC1-family-protein	unknown	unknown	gnl\|CDD\|369440
NZ_CP011271.1\|WP_052554030.1\|4218981_4219947_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238910
NZ_CP011271.1\|WP_082840434.1\|4201509_4205013_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NZ_CP011271.1\|WP_082840436.1\|4206558_4207485_-\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|224165
NZ_CP011271.1\|WP_157469586.1\|4225668_4225815_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_157469582.1\|4214829_4215078_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_162271746.1\|4220408_4222436_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379276
NZ_CP011271.1\|WP_082840438.1\|4211657_4212557_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238121
NZ_CP011271.1\|WP_162271745.1\|4213801_4214812_+\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP011271.1\|WP_052554016.1\|4207456_4208800_-\|asparagine-synthetase-B-family-protein	unknown	unknown	gnl\|CDD\|238949
NZ_CP011271.1\|WP_082840441.1\|4215386_4217303_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082840442.1\|4219992_4220451_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_157469580.1\|4209206_4211342_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225177

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_052554034.1\|4223147_4225181_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.37696e-104
NZ_CP011271.1\|WP_082840435.1\|4205037_4206543_-\|hypothetical-protein	gnl\|CDD\|223717	COG0644, FixC, Dehydrogenases (flavoproteins) [Energy production and conversion].	1.97346e-15
NZ_CP011271.1\|WP_052554009.1\|4198559_4199693_-\|hypothetical-protein	gnl\|CDD\|227005	COG4658, RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD [Energy production and conversion].	0.000417511
NZ_CP011271.1\|WP_082843336.1\|4199689_4201468_-\|CRTAC1-family-protein	gnl\|CDD\|369440	pfam07593, UnbV_ASPIC, ASPIC and UnbV. This conserved sequence is found associated with pfam00515 in several paralogous proteins in Rhodopirellula baltica. It is also found associated with pfam01839 in several eukaryotic integrin-like proteins (e.g. human ASPIC) and in several other bacterial proteins.	1.84023e-16
NZ_CP011271.1\|WP_052554030.1\|4218981_4219947_-\|hypothetical-protein	gnl\|CDD\|238910	cd01935, Ntn_CGH_like, Choloylglycine hydrolase (CGH)_like. This family of choloylglycine hydrolase-like proteins includes conjugated bile acid hydrolase (CBAH), penicillin V acylase (PVA), acid ceramidase (AC), and N-acylethanolamine-hydrolyzing acid amidase (NAAA) which cleave non-peptide carbon-nitrogen bonds in bile salt constituents. These enzymes have an N-terminal nucleophilic cysteine, as do other members of the Ntn hydrolase family to which they belong. This nucleophilic cysteine is exposed by post-translational prossessing of the precursor protein.	6.36905e-14
NZ_CP011271.1\|WP_082840434.1\|4201509_4205013_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	3.80358e-13
NZ_CP011271.1\|WP_052554028.1\|4217304_4218954_+\|hypothetical-protein	gnl\|CDD\|224196	COG1277, NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only].	0.000157167
NZ_CP011271.1\|WP_162271746.1\|4220408_4222436_-\|hypothetical-protein	gnl\|CDD\|379276	pfam13578, Methyltransf_24, Methyltransferase domain. This family appears to be a methyltransferase domain.	8.39716e-19
NZ_CP011271.1\|WP_082843335.1\|4197737_4198544_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	3.79165e-117
NZ_CP011271.1\|WP_052554016.1\|4207456_4208800_-\|asparagine-synthetase-B-family-protein	gnl\|CDD\|238949	cd01991, Asn_Synthase_B_C, The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the assembly of asparagine from aspartate, Mg(2+)ATP, and glutamine. The three-dimensional architecture of the N-terminal domain of asparagine synthetase B is similar to that observed for glutamine phosphoribosylpyrophosphate amidotransferase while the molecular motif of the C-domain is reminiscent to that observed for GMP synthetase .	2.5674e-12
NZ_CP011271.1\|WP_162271745.1\|4213801_4214812_+\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.14877e-46
NZ_CP011271.1\|WP_082840436.1\|4206558_4207485_-\|radical-SAM-protein	gnl\|CDD\|224165	COG1244, COG1244, Predicted Fe-S oxidoreductase [General function prediction only].	2.87676e-27
NZ_CP011271.1\|WP_082840438.1\|4211657_4212557_-\|hypothetical-protein	gnl\|CDD\|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	5.79777e-38
NZ_CP011271.1\|WP_157469580.1\|4209206_4211342_+\|hypothetical-protein	gnl\|CDD\|225177	COG2268, COG2268, Uncharacterized protein conserved in bacteria [Function unknown].	1.02923e-34

>NZ_CP011271.1|WP_082840439.1|4212658_4212934_+|hypothetical-protein
MEIEWTDADPESGEKRFVRAEKFARKWHFKVRFRRRTNWAAVTNPSREMWETLLDALERRYPRREGVTDEDLKQVRAVVAGLEPSEGDQPV
>NZ_CP011271.1|WP_082840438.1|4211657_4212557_-|hypothetical-protein
MLLFEAHKHETSEVAHKAIVSIAFSPDGSTIATGGRDGTVLVRDADGNVASLLERGPKVLPVYSVGFQSNGTALVIGRAFGWMIYKQAGEKWGEFTSKSSSVTSLAVLSDQLIAIGTGDRTKASGGWFELWDTIKDRKAPRPFSEPNGVRVIAASPKNKLVAWATGHRKVRVWDITTPAPIDFPQERDCPAIALSTDGSMLAAAGDWNAKIYDLKTKRERVVLKGHKGQVLSVAFSPDGSTVVTGSFDSTVRLWDTATGKERANYQWDIGVVHCVTYAPDGFRLAAGGDSGRVVVWDTE
>NZ_CP011271.1|WP_157469580.1|4209206_4211342_+|hypothetical-protein
MFALVATDDVSSPAALYGLLAVAGLCSGIVFWWLTVRVIPNDKVGVVEKLWSPKGSVTGGRIIALHDEAGYQAALLRGGLHFGYWRWQYRIHVAPLVTVSQGQIGYVYARDGQPLPPSQTLGRVVECNNFQDAQVFLARVGEEADYGQRGRQRAILREGVYAINPAAFVVMTENGAYSLPHLLEAQEADAIGAWHEQLTACGGFQPVVIGGSSKTGETEVHDDLIGVVTVHDGPSLPPGEIIAPAVGTEPDGASYHNNYQDSEAFLKAAGRRGRQSAPLTDGTYFINRWFASVELVAKTVVPIGHVGVVVSYVGRAGRDVSGTGFRHGERVQDGERGVWERPLGPGKYPFNVYAGQVILVPTTNFVLHWVTGRTETHKFDEALRSIDLVTRDAYEPLLPLSVVVHIDYQRAPSVIQRFGDVKKLITQSIDPMLSAYFRDVAHKKTMLQLLHERDLIQAEARAELRTRFREFDVECVDVLIGKPVAHEKDSKIEALLEQLRLRQLSIEQLETYERQRTAAEKLRTLNEAQAQAAVQVQLTNARAEIQIAESRGEAELARARKQSEQMVVTADAELARAKRQAEQTVLTAEAHAKEQVLAGRGEGQKALQIGLSEAAVVLRKVAAYGDPRLYAASLLADRLADSTQPLVPERMFVSGANGESGVAGGPLNALLTLLLGEKTGLGSFADSPEAIEFKGECDQLAREAMGTLTGK
>NZ_CP011271.1|WP_052554016.1|4207456_4208800_-|asparagine-synthetase-B-family-protein
MHRTLPLSRVIDLTDAAGNRVYNMTVDEARELVATGDAGAVGRIEGEFALIGQRGRTIFFARTIGRLLRYFIAKWHDGPILIVADRIDAIRDQLNILGLGDQFHPSYTRMVPAHHVMRLELVGCPDPSPTCDRFFAPTRNSLPADPNTIGERYIGAAYNEIVRWLDRVPAREPIGVCFSGGVDSGSVFLLTYHALLQRGDSPSRLKAFTLEVDGGSPDLDQAREFLSRLGLELFLEPISVRSSDVKIEDAIRVIEDYKPLDVQSAAMALAMCRGIRARYPEWKYLLDGDGGDENLKDYPIEDNPELTIRSVLNNLMLYQEGWGVQAIKHSLTYSGGQSRGYARTYAPLSVTGFTGLSPFVCPSVIEVAEGIPFIELTNWDHEKLYALKGQVVAAGVKVVTGLDMPVFPKRRFQHGATTKPKDLFPASPAAYRRIFQRVYDAGAALHG
>NZ_CP011271.1|WP_082840436.1|4206558_4207485_-|radical-SAM-protein
MTPVPLFTDDWVLARRPARNALTAGRPYAWLVEPEPAADGRLVNVATLFLTNRECPFRCVMCDLWKNTLPESVGVGQIPEQIRWALAQLPPAQHLKLYNAGSFFDPRAIPPEDYPEIVRLAAPFERVIVECHPKTIGKRCESFHAMLANQGVKLEVALGLETVHPEVLLRLNKRMTTDDFAQAARALRTAGVTVRAFIMVRPPFLTEDEGLEWAKRSIDFAFAHGAECCSLIPTRDGNGAMEELARAGHFAPPALETLERALEYGLAQRAGRVFLDLWDIGKVSPDAPDREARVARLARMNLSQHLEP
>NZ_CP011271.1|WP_082840435.1|4205037_4206543_-|hypothetical-protein
MTRFDCDLAILGSGFGGTLLAIIAQKLGYSVVLLERGRHPRFAIGESSTPLADFKLADIANRFGLDWLRPFAKYGPWKATNPHLPCGLKRGFSFFRHERGQPFTPRDDNANTLIVAASPNDETADTHWFRAEFDSHLVDRAVEAGVPYLDNLETHAVRHDSRGWELDGTRGDETVAVRAGMLIDATGTGQVIASALGIESVDPTQLRVKSRALYSHFTGVAPWQSVLEEQYGTAATAGHPFPCDAAALHQIIDNGWMWVLRFENGVTSAGFSLDPSAHPIVPGESPEAEWSRLLNTYPSLARQFARAVPVRPFVRTGRLQRRLSRAAGADWALLPHGAGFLDAWLSPGIAQTLFAVNRLGRILAEERAGPGRERRLNEYGQTVLRELAWVDEITGTCFACLDRFPVLVSVTALYFVAAIYCEEREQAGLASPDDAFLLTDHPEYRAVADHIFRKGAGLPAADADAFAAEVRERLAPYNSCGLCDPDRCNMYPYTGSLSPLR
>NZ_CP011271.1|WP_082840434.1|4201509_4205013_-|tetratricopeptide-repeat-protein
MASYLHRHRSKLIAAVVVLLVAAGATAFFVWKRQTRLPGPGEPTYEQFVEVFELGSAALDVDVWDVAETNLNQAVVLVPQEPAAWANRALLNFRTARFPDAERDLKEAERLSPDNPDIAKLRGVLEERGGRYTEAIASLRKATEKDRDDIQALFFLAQTIIKEQKPDSDAEYQRLLEQILAARPNNRYARLELLRAAVRRADRTAVKDVTARLKAEIPSWTFEGGDKIRASFEEWEKASTGPLDDNALFALTPFANLYLAAPGYAQDATDINPRGGYRGYPLRTFLRLAPVRPSLAPADTELTFTTEPLENAPAGRWATAVPVWLTGEGNPVVFLAGASKVRRVGAPTALPALPAASDGLVALDWNNDFRTDLFVAGPKGVQFYEQGAEGNFTDVTAKTKLPADILKGDFAAALAADVDLDGDLDLLLARRTGAPVLLRNNLDGTFTAQPIFPDVDSGRAFAWADLDHDGAADAVVLDARGRLHVFANERSGVFKRWPTALPDGQYLAVNISDADDDGTFDLIALRADGAILRISDRNKRASWDVAELGRWDNLAGSEPGSVHLLIADLDNNGAPDLIASRASGSAAWLGSGNGKFERLSATLPPNVVATADLTGTGRLDLLALDAEGRPTRSRNVGKKEYHWQSIRFRAAPGPAEGDNRINSFGVCGEIEFRTGTHVVKRPITGPVSHFGLGTRTKCDVLRIQWPNGTPQIEFARAIDQTVVAEQRLKGSCPFLFTWNGERFVFVTDFMWSTPLGMYINAQDKGGFLQTTEWVKIRGDQLVPRDGHYEVRVNANLWETHYFDHLSLRVIDHPPGTELYVDERFALEPSKPAFHLTQPTRPVAQAWDHRGADVTSVVRAVDGEYLDRAGRGLYQGITNDHWVEVDLGADAPREGPVWLVAHGWIHPTDSSVNYALEQGQNTRPRALTLEVPDGKGGWKVARDKIGFPAGKNKSVLLRLDGLDGPGVARRFRLRTNMEIYWDALHYARGAGDAQIAEKELHPTVADLRFRGIVAMTQANRSSPELPHYDQLVAEGQPWRDLIGYHTRFGDIRELLAKTDDRYAILTAGDEIVLRFAALPAPPPGWTRDFVWVSDGWVKDGDLNTRFGKTVLPLPAHNMASYDVPPTTLENDPVYRRFRKDWDVFHTRYVTPNQYERGLRNFKRRGEQP
>NZ_CP011271.1|WP_082843336.1|4199689_4201468_-|CRTAC1-family-protein
MLVLVVVLNRSDRASENNLGADESLKRYGFHLAESSKQCGINFQHESPVLDPKFNHIMPVVAAMGAGVSIVDFDGDDLLDLYVVNSKEGKSNHLYRNRGDGTFEDVAGAMGVADLNRAGTGACMGAIWADMDNDGYPDLFVYKWGKPELFRNKQGKGFERVTDRAGLPRWVNANSACWLDYDRDGLPDLFIAGYWPENVDLWNLETTKVMPESFEYAKNGGRKYLLRNRGGGTFEDVTEKVGIKSTRWTLGVVAADLCGTGYPDLVLANDYGVSEFFANKGGERFEEVGEETGIGLSPKSGMNASLGDVLNKGQLAVYISNITEAGNLVQGNNLWVPAGKTPNGRPRYLNQAGSLNVELGGWSWGAKFGDLNNDGRLDLYLTNGYISSAKGKSYWYDYGKIAGGLKGLIREAQYWPPIGDQSLSGYQQKCLWINRGGSFTDVGTAVGVTDTFDGRAVALGDLFNRGVVDVAVANQSGPLLLYKNTVAPGRDWVQFALTGGARPGREKGWSNRSAIGAQVRLSWRQGTGPLQEQLQVITAGDGYASQNMFRLHFGLGTDAKIEKADIIWPSGRTQTIHSPKSGITHRVEESGP
>NZ_CP011271.1|WP_052554009.1|4198559_4199693_-|hypothetical-protein
MTPSPAPIGPLPRASDQSWSGTVWRLPATAALVGVFYVARGALLGQSAVAVDPATTRVAAITLLLVSLLALWWRVVARDPRLHAPILITAILALSDASFGLLENHPAPPWLVSLTNGMVLEYSPTFVTMTVTVLCELVIGRFMWGKWPNLASAYISGISAGILVKSSLLWPFIMCGLISITSKYVLRLHNRHLWNPTNFGMTTMLFLAPEHVASLSVQAGNNGWAVATIWILGGLIMYNLGRFHMPFAFVLAFVPLAFLRSGVTGHPWQAELAPITSPMFQLYIFFMITDPKTTVRGRWNQIAFVIVVAAAETFCRLVFKDVHSLYHALFFVGPAANLVEIYSDRARKRRATRATALPMEEAPEPVPAGEPAVLTKT
>NZ_CP011271.1|WP_082843335.1|4197737_4198544_+|ABC-transporter-ATP-binding-protein
MSDAVGAGEGAALRARAVGKTFATTEGTRVVALDRVALDVGAGELVSLVGPSGCGKSTLLRLVAGLDLPTEGELWVGSTLITGPSAERGVVFQDPSLFPWLTIRRNIESGLVARGVLRSKRHEVDEYLRLVGLEGFANAYPHQLSGGMAQRAALARALINHPRVLLLDEPLGALDQFTRMRMQDEILRMWQARGTTMLLVTHDIDEALYLSDRIAVMTPRPGRIDRILDVDLPRPRQRNDRRFLEHRARLLELLHLTGGIEEPLIPGA
>NZ_CP011271.1|WP_162271745.1|4213801_4214812_+|protein-kinase
MSALPNIRSTTPGAFAFAVGAEPSPGYRLRCVRGRGGFAEVWEAEAPSGPPVALKFMPTSNTNTTARELRSIQSFQSLEHPYIVKTYDVWSVPGYLVVNMELAEATLLDLMLVYRDDLGQELEPATLCLYLWQVAEALDFLNARQHVRDGRRVGFQHGDVKPNNILLFGDTAKLTDHGLATATFGPSTPCSRQGTREYAAPEVFLGSITDWSDQYSLAITYYALRCGRFPFPPPVKNASRSSLRPFADLSGVTEPERAPLLKALAPVPQERFPNCCEFMSAVLKSLNLRVDFGDADTPMKVVPATIRSGSNIFRRPAGPPASHGTLRRPPFSNPGS
>NZ_CP011271.1|WP_157469582.1|4214829_4215078_-|hypothetical-protein
MTSRMWVVIALIALVQATGCCQHCCCLSDRDSRSPTRDTYRDDRPPHVSGADTLPPANLPTSPGAAPSSGPPKVTGAYGGVE
>NZ_CP011271.1|WP_082840441.1|4215386_4217303_+|hypothetical-protein
MAIEFNCPHCQHAYRLKDEFAGKSATCKTCRAKLTIPQPVVVAGGAPRLTAEEIAEAEAKALAALADEQAQVEKDAAAQFIPIECQHCNHKWTEPLAKAGKNALCPECRQRVKIPEPKNDAPVPWNQERSKLPSMAKQNFEKLANVQDAADAKFVSGKALTQAGADGIEYEPRPLKQKVTFALVIVGALLGTTLGIRSCYVGRVERGEDRLMVEAQEEFAKSTGALPANDAPPEAQLCSALLYIAGGEHAARHKEPKIKEALEQFAKARDAIRKAPPSLSRNAVGGELAVAILILGGSEQQARDQVRIRWTPGTDLKTRPNERLYTVLDELRQSLELLRAAEFEFKNHLARRLSRELTKQGQGLLAVEMIPLALFNEKEQDEAKASIALEVLRTDKGSDLPRRVMGDLKGRGPELMKSVPTPASAQTLFFAVDPEKAPRIIAPPAGESMLESSRFAYVGKALVENQPDVAVQLAQRRGPPEGQIRALALCADWSADPGPALDAAQAILSANKGRKEISAFSVLRLAQIAAEKNKPDLAKELANLIADDGMKAWARGAIVQARSGAGSKDKADESWVELPPADKPKEVRAGHAWGLLWVARQNTRLSGDHSAELKIVNTWPTVGIPFGKAGIALGLQDN
>NZ_CP011271.1|WP_052554028.1|4217304_4218954_+|hypothetical-protein
MWPFGLFGSLAAWELRRIARRGLATRVRLILLYTLFLAFIAFATLWFQPQVPARDVFFGRPGVLAPAELARFANAFALTLLEVQLVAVVALAPALAASAVSEEKYQQTLPLLLITLLTDREIVFGKAAGRIAFVLAALFAGLPVLMITQLFGGVSTAFLAAAYSVTAGTVVLCAAIGVSAACYAPDLRSAVLRAYTRIAIFVCGAFVPPFVFASPFGVLVVLASEPINEQFVGLAFGYPLIQVLVGSLFLINAVRALRLRDATAGPPPATAYPEPPKPAEPPLLQPEDEVPPDLPPIDAGDPVLWKERCVGWRPKWAPLALSKFMGFVAGTVAIGLFACGMWIFLARVAKGFDPSEIERYSGQSGGLETGSWLLVGAGVFAGGRYLLPLAVGLSGAIAGERFRGTLDVLLTTTLDRHAVLRAKIQAQVERGTVFGAVAVAAVGTAFIADAGIRVGLAAAGLTAIAMALVVAVGAWFTVRCASDARAFRLLLPVTMLVVGWPVFVWNLLRGEAPVPPQILFWGLVSAACVCGVAGLVFWVHAAHVLSRGE
>NZ_CP011271.1|WP_052554030.1|4218981_4219947_-|hypothetical-protein
MQITNSEGYSYEPVRVVGHVPPYPADLVAKSKDLLTATCGLFKKLGPVAHVAPHVFAKYKVHADRARTSAAVIGVEPVDLLAANLCYDLLMGASAMGCSTLALAGPDGPVLARNMDWFPAEKVAKASCLVTEEYGVNAGFLGMLGAVTGLSSHGFCVCLNAAFGGSDPDGYPMLLFLRHVLDTATNYRAALEMITTERLMSGGIITVVGTRNEERAIVERAPRRATVREARGSEPLLATNHFRDLSTPEECPRYAHMAAFVGQVRPLNLLTSKHVLQEITAQHVVMCPATQTAEMFVPSHLLPESVCEEMTLADLYRYFLN
>NZ_CP011271.1|WP_082840442.1|4219992_4220451_-|hypothetical-protein
MLDFLASRFGVRTLIDVGCNSPETVYRARRKSIRAVGVSGDPQVARDCQVIIEHDYCRKPLFAGEFDLGWSVGFLEHIEDQFAPNILATFQGCRVVFVAGTDSAVERWAELLQQAGFTFDPDATEGARRRSTMEGGTTRTTGLVFRRGESLG
>NZ_CP011271.1|WP_162271746.1|4220408_4222436_-|hypothetical-protein
MERTLASVRASDWPGAPVVLRQPADWPVGWQSTSRMYRTVLQRAWGDGCWWAVVLEDDVQVNRHLWANLTRWHPITTGQLHWGSLFVPDTIHDPWARTCPELGYRLARPALTTGPNAQWQKARLWGSQAYVFSRGGLGAMLDQWDRHGGGQDARAVTIAGGAGWPLWYTSPCLVEHVPVISAFGTPPAYAPDFVPGFRFVPEPADTYRHPEGVPGWLSFAEGRALWELARDKRVLEFGRFRGRSTVALAQSAREIVSVDVLDSAPAAGWLERFGCPPNVTFFQCHFAELDPHLGPFDLVFVDGEHDAAHVRADMELALTRLAPDGYLACHGYPDPDWPDVRRVVDEIAAARGLVRVCQADYLAVFQVSDPARTQEVPEPAPLIATSSIDSLPMETVRTPRTVWVYWEGPMPGYIELCCETIRAHNRHVRVEVLDRGGFDALFLHDRDLPIDALILPHKADFIRAYLLAHYGGLYLDADCIVLTSLDFVFDLADANGFVGYRDPLGYMSASFMTSAPGGAVIRDHYERVCAVLRSRRERGWLDLSSVPLDQAVAAHPKWAHILPTERVMPISWQASERLSERHSDAVHELSFRSDAAMYMLSNNTIKSRRATRVLAHMPPPTCWWTVTSSRSCFAARWGARNWCQKSSTHTTPTSEPKSSMKACSTSWRPGSGCGR
>NZ_CP011271.1|WP_157469584.1|4222586_4223039_-|hypothetical-protein
MNVLVSGTGSGSGSFPGGTICVRGSTGDGDTAGSLPLTVRVRVVAGHVPPVGSAEPKQTYDVDVTPVGGQWCATGVPVSGSTPAGVPLTALAWLRTGPSWSGPDGVWFYGGGPNPTGCCPTSPLEQSAPVAGAFQGWPPPPPPLPSDITG
>NZ_CP011271.1|WP_052554034.1|4223147_4225181_-|serine/threonine-protein-kinase
MNRTPEAPQSAPRACPTPAELAAFLSDELPAPTMDEIGAHVSSCKSCDAAVRRMDEVTHSKFRKPARSSQNNVGPSDPTLPDYPYVLASSRSLPPTQVHYVVPKPPERLGQYRIMERLGQGGMGTVYRAEHARLKKFFAVKILSASQMWDHRAVARFQLEMEVVGRLDHPNIVRATDAGDVDGLHFLVMELIEGSNLAKLINRCGPLPVPVACELVRQAALGLQHAHENGLVHRDIKPSNLMLSTSGQVKVLDLGLALLRSNDPNPNDDELTGAGEVMGTAEYMAPEQWANTHAVDVRADIYSLGCTLYALLAGDPPFSGTERKTFMRLMTAHQTEAAPPITTRRPELPAPLVALLDRMLAKNPDDRPATPGKVADALKSLSDERGLSKLSGLSVSGAESNDLSASETPTSFFPATVKIQPRPRRRRWRGVAALVLVLGGAGIGGYTAFAPAPVPNQAKQPLPPEEPPHDPKKWRNLLTAQPTERLWRASQIAFFDFNPKKELLSVRSPSKSLLRLGETQAKGYKLQVGLRQVTWEGGVGIYFGGGSPSQEPNEFRCQLIHLVHVGLPGNAAKYSLSRSRGNLVRLTDQRPDLQVWGFSGTPVASPGPKEHLLELEVRPECVWSIRWDGAECSELTNEFALSQQRRMLPDPHLIGEYGIYCNGADVSVLTARYIETE
>NZ_CP011271.1|WP_157469586.1|4225668_4225815_+|hypothetical-protein
MMQADSIDRNDLYRLADDGCPHSPTSDTSAHDLSALWIALGKDDRRAE

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Crispr_ID: NZ_CP011271_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_12

4786708-4786813

Orphan

Consensus_repeat	Method
ACCTCCATCGAGATGCCACGCGGCTATTGAGCAACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_12

>merge|NZ_CP011271|12|4786708-4786813|CRISPRCasFinder
ACCTCCATCGAGATGCCACGCGGCTATTGAGCAACCTTGGGCGGAACCTTCCGAGACATGGCCCGAACGAACCTCCATCGAGATGCCACGCGGCTATTGAGCAACC

>NZ_CP011271|12|12|4786708-4786813|CRISPRCasFinder
ACCTCCATCGAGATGCCACGCGGCTATTGAGCAACC	TTGGGCGGAACCTTCCGAGACATGGCCCGAACGA
ACCTCCATCGAGATGCCACGCGGCTATTGAGCAACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_082840728.1\|4802594_4803074_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082840725.1\|4794479_4798526_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|173412
NZ_CP011271.1\|WP_162271779.1\|4783212_4783917_-\|ISAs1-family-transposase	unknown	unknown	gnl\|CDD\|376573
NZ_CP011271.1\|WP_157469649.1\|4784927_4785206_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082840726.1\|4798566_4799424_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082840278.1\|4782395_4782950_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379282
NZ_CP011271.1\|WP_052555019.1\|4786213_4786474_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274340
NZ_CP011271.1\|WP_082840727.1\|4800842_4802519_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|143476
NZ_CP011271.1\|WP_082840723.1\|4788887_4789241_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380386
NZ_CP011271.1\|WP_052554838.1\|4781682_4782357_-\|ISAs1-family-transposase	unknown	unknown	gnl\|CDD\|379382
NZ_CP011271.1\|WP_082840730.1\|4804040_4804838_+\|biotin--[acetyl-CoA-carboxylase]-ligase	unknown	unknown	gnl\|CDD\|319741
NZ_CP011271.1\|WP_082840721.1\|4783670_4784150_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379382
NZ_CP011271.1\|WP_082840724.1\|4789400_4794398_+\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|131281
NZ_CP011271.1\|WP_082840729.1\|4803168_4804044_+\|carboxylating-nicotinate-nucleotide-diphosphorylase	unknown	unknown	gnl\|CDD\|238806
NZ_CP011271.1\|WP_162271778.1\|4779119_4780448_-\|IS4-family-transposase	unknown	unknown	unknown
NZ_CP011271.1\|WP_052555030.1\|4799504_4800653_+\|twin-arginine-translocation-signal-domain-containing-protein	unknown	unknown	gnl\|CDD\|238362
NZ_CP011271.1\|WP_157469651.1\|4786003_4786156_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082840722.1\|4786836_4788705_-\|threonine--tRNA-ligase	unknown	unknown	gnl\|CDD\|237050
NZ_CP011271.1\|WP_157469540.1\|4781200_4781686_-\|ISAs1-family-transposase	unknown	unknown	gnl\|CDD\|227720
NZ_CP011271.1\|WP_162271725.1\|4780649_4781156_-\|transposase	unknown	unknown	gnl\|CDD\|315923

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_082840730.1\|4804040_4804838_+\|biotin--[acetyl-CoA-carboxylase]-ligase	gnl\|CDD\|319741	cd16442, BPL, biotin protein ligase. Biotin protein ligase (EC 6.3.4.15) catalyzes the synthesis of an activated form of biotin, biotinyl-5'-AMP, from substrates biotin and ATP followed by biotinylation of the biotin carboxyl carrier protein subunit of acetyl-CoA carboxylase. Biotin protein ligase (BPL) is the enzyme responsible for attaching biotin to a specific lysine at the active site of biotin enzymes. Biotin attachment is a two step reaction that results in the formation of an amide linkage between the carboxyl group of biotin and the epsilon-amino group of the modified lysine.	3.56131e-46
NZ_CP011271.1\|WP_082840724.1\|4789400_4794398_+\|VWA-domain-containing-protein	gnl\|CDD\|131281	TIGR02226, hypothetical_protein-transmembrane_prediction, N-terminal double-transmembrane domain. This model represents a prokaryotic N-terminal region of about 80 amino acids. The predicted membrane topology by TMHMM puts the N-terminus outside and spans the membrane twice, with a cytosolic region of about 25 amino acids between the two transmembrane regions. Member proteins tend to be between 600 and 1000 amino acids in length. [Hypothetical proteins, Domain].	8.26624e-13
NZ_CP011271.1\|WP_082840278.1\|4782395_4782950_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379282	pfam13592, HTH_33, Winged helix-turn helix. This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.	8.41644e-14
NZ_CP011271.1\|WP_082840723.1\|4788887_4789241_+\|cupin-domain-containing-protein	gnl\|CDD\|380386	cd06981, cupin_reut_a1446, Cupriavidus pinatubonensis reut_a1446 and related proteins, cupin domain. This family includes bacterial and some eukaryotic proteins homologous to reut_a1446, a Cupriavidus pinatubonensis protein of unknown function that may be related to mannose-6-phosphate isomerase. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	9.90758e-52
NZ_CP011271.1\|WP_082840727.1\|4800842_4802519_+\|hypothetical-protein	gnl\|CDD\|143476	cd07560, Peptidase_S41_CPP, C-terminal processing peptidase; serine protease family S41. The C-terminal processing peptidase (CPP, EC 3.4.21.102) also known as tail-specific protease (tsp), the photosystem II D1 C-terminal processing protease (D1P), and other related S41 protease family members are present in this CD. CPP is synthesized as a precursor form with a carboxyl-terminal extension. It specifically recognizes a C-terminal tripeptide, Xaa-Yaa-Zaa, in which Xaa is preferably Ala or Leu, Yaa is preferably Ala or Tyr and Zaa is preferably Ala, but then cleaves at a variable distance from the C-terminus. The C-terminal carboxylate group is essential, and proteins where this group is amidated are not substrates. This family of proteases contains the PDZ domain that promotes protein-protein interactions and is important for substrate recognition. The active site consists of a serine/lysine catalytic dyad. The bacterial CCP-1 is believed to be important for the degradation of incorrectly synthesized proteins as well as protection from thermal and osmotic stresses. In E. coli, it is involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). In the plant chloroplast, the enzyme removes the C-terminal extension of the D1 polypeptide of photosystem II, allowing the light-driven assembly of the tetranuclear manganese cluster, which is responsible for photosynthetic water oxidation.	2.82882e-56
NZ_CP011271.1\|WP_162271779.1\|4783212_4783917_-\|ISAs1-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	5.38369e-11
NZ_CP011271.1\|WP_082840721.1\|4783670_4784150_-\|hypothetical-protein	gnl\|CDD\|379382	pfam13808, DDE_Tnp_1_assoc, DDE_Tnp_1-associated. This domain is frequently found N-terminal to the transposase, IS family DDE_Tnp_1, pfam01609 and its relatives.	6.53497e-27
NZ_CP011271.1\|WP_082840729.1\|4803168_4804044_+\|carboxylating-nicotinate-nucleotide-diphosphorylase	gnl\|CDD\|238806	cd01572, QPRTase, Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with 5-phosphoribosyl-1-pyrophosphate (PRPP) in the presence of Mg2+ to produce nicotinic acid mononucleotide (NAMN), pyrophosphate and carbon dioxide. QPRTase functions as a homodimer with two active sites, each formed by the C-terminal region of one subunit and the N-terminal region of the other.	3.16773e-133
NZ_CP011271.1\|WP_082840722.1\|4786836_4788705_-\|threonine--tRNA-ligase	gnl\|CDD\|237050	PRK12305, thrS, threonyl-tRNA synthetase; Reviewed.	0
NZ_CP011271.1\|WP_052555030.1\|4799504_4800653_+\|twin-arginine-translocation-signal-domain-containing-protein	gnl\|CDD\|238362	cd00688, ISOPREN_C2_like, This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate complement. Class II terpene cyclases include squalene cyclase (SQCY) and 2,3-oxidosqualene cyclase (OSQCY), these integral membrane proteins catalyze a cationic cyclization cascade converting linear triterpenes to fused ring compounds. The protein prenyltransferases include protein farnesyltransferase (FTase) and geranylgeranyltransferase types I and II (GGTase-I and GGTase-II) which catalyze the carboxyl-terminal lipidation of Ras, Rab, and several other cellular signal transduction proteins, facilitating membrane associations and specific protein-protein interactions. Alpha (2)-M is a major carrier protein in serum and involved in the immobilization and entrapment of proteases. PZP is a pregnancy associated protein. Alpha (2)-M and PZP are known to bind to and, may modulate, the activity of placental protein-14 in T-cell growth and cytokine production thereby protecting the allogeneic fetus from attack by the maternal immune system.	4.15257e-11
NZ_CP011271.1\|WP_157469540.1\|4781200_4781686_-\|ISAs1-family-transposase	gnl\|CDD\|227720	COG5433, COG5433, Transposase [DNA replication, recombination, and repair].	0.000513124
NZ_CP011271.1\|WP_082840725.1\|4794479_4798526_+\|hypothetical-protein	gnl\|CDD\|173412	PTZ00121, PTZ00121, MAEBL; Provisional.	5.36327e-11
NZ_CP011271.1\|WP_052555019.1\|4786213_4786474_-\|hypothetical-protein	gnl\|CDD\|274340	TIGR02890, conserved_hypothetical_protein, regulatory protein, yteA family. Members of this predicted regulatory protein are found only in endospore-forming members of the Firmicutes group of bacteria, and in nearly every such species; Clostridium perfringens seems to be an exception. The member from Bacillus subtilis, the model system for the study of the sporulation program, has been designated both yteA and yzwB. Some (but not all) members of this family show a strong sequence match to Pfam family pfam01258 the C4-type zinc finger protein, DksA/TraR family, but only one of the four key Cys residues is conserved. All members of this protein family share an additional C-terminal domain. Smaller proteins from the proteobacteria with just the N-terminal domain, including DksA and DksA2 are RNA polymerase-binding regulatory proteins even if the Zn-binding site is not conserved. [Unknown function, General].	2.68299e-08
NZ_CP011271.1\|WP_052554838.1\|4781682_4782357_-\|ISAs1-family-transposase	gnl\|CDD\|379382	pfam13808, DDE_Tnp_1_assoc, DDE_Tnp_1-associated. This domain is frequently found N-terminal to the transposase, IS family DDE_Tnp_1, pfam01609 and its relatives.	1.27678e-16
NZ_CP011271.1\|WP_162271725.1\|4780649_4781156_-\|transposase	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.75898e-32

>NZ_CP011271.1|WP_052555019.1|4786213_4786474_-|hypothetical-protein
MIVPQPCARCGGEIPPERVEAMPETMVCVACSQEMGGEFTVIMTPERISKEGSLKKNYGGYSTRKIRKPIQPKNSEWSSSRIVDSV
>NZ_CP011271.1|WP_157469651.1|4786003_4786156_+|hypothetical-protein
MEHRNHVLQEMRAELGLETTRGWREKTVLRAAPCLFGLYTVVALLFHARP
>NZ_CP011271.1|WP_157469649.1|4784927_4785206_+|hypothetical-protein
MILPTEAHPLVQVLALNFTSPTYQRFSTLMVAALVTTGRRTVANVLRTLRHLAPGHRTDYQRTLVRASTRLRPDAVHTRLPAPHWSRDAGRR
>NZ_CP011271.1|WP_082840721.1|4783670_4784150_-|hypothetical-protein
MSKPEMRCARYFADLPDPRVDRTKWYRLDDILVITLCAVICGADSFEEIERFGDAREEWLRTFLALPNGSPATTRSTGCSRCWTGTSSRRASGHGWRTCARAPGCGPSRSTGRRAGPRPGTRSAGARTWSTRGPPRTTCSWARCRCPTGPMRSRPCLSC
>NZ_CP011271.1|WP_162271779.1|4783212_4783917_-|ISAs1-family-transposase
MLSVLDRDQFSACFGAWMADLCEGTGLRAIAIDGKACRAAPGDTFSGCPHLVNAWATENNLFLGQVPVPNGSNEIAAVPELLKVLDLRGALVTLDDAFGQKDVVTQIREQGGAYLVTVKGNQPTLHRAVVAVFEKAAEAEFAGCDMASSVEDGHGRHEERYVTVIRDPEGVPEEWAGVGAVVMVSRERAVSDRNASSAHYLTSLWASADELARYIRGHWGVENGLHWCLDVPFR
>NZ_CP011271.1|WP_082840278.1|4782395_4782950_-|helix-turn-helix-domain-containing-protein
MALTLPDGVLDALRLRALRACERGFTHADVADILGVATETVCRWWVAYSTGGPEAIPHERTGRPPGSGAALSDEHATRIQRLIDTTTPEDQGLTFPLWSRRAIGELIRTDCDVLLAVRTVGEYLRRWGYTAKKPARHAEKQDPEEVRLWLEYTYPALKARARKERAEVHQGHSLFHLVGLGWCR
>NZ_CP011271.1|WP_052554838.1|4781682_4782357_-|ISAs1-family-transposase
MPACTLHEAFAALPEPRGTHGLIHPLPAVTGLVVLAMLMGRKSLQGIARFGRQHGAPLAHALGFRRGKTPAASTLSRTLRRFDAPQLEATISQWIRDRIAPRAFEQISIDGKTLRGSRDGDVPGQHLVAAYAPAVEAVLAQVRVGSKTNEHKAALGLLGILPLQGRVVVGDAMFCQRDVAEQVIDRGGEYLLVVKDNQPGLEADIEGGFAFETAARGIAAATSP
>NZ_CP011271.1|WP_157469540.1|4781200_4781686_-|ISAs1-family-transposase
MKTCFSAPADRVVTTSEKGHGRIEKRTLESTPILTAGQKWKGLKQGLRITRERTVKGNRTVEVVYGITSLSMERANAATLRAILRDHWQIENGLHYVRDVTLGEDACRVRKGTAPPVLAAVRNVVIHLLADVDAKSRPEALELLQLDPARARNLIGIPQTE
>NZ_CP011271.1|WP_162271725.1|4780649_4781156_-|transposase
MADHCSGYGYAKRGERATMDVPDPHIGINMVSSITNEGALRFMTYPGTMTGERFVVFLGRLLRTTTGKIVLIVDRLKAHQSGVVKEWVAAHADRLEVFELPRRAPERNPDEYLNNDVKRAVTEDGLPGSKPALRERLQHVMRTLGHLPKHVVSYFLQPCVLYAAATAT
>NZ_CP011271.1|WP_162271778.1|4779119_4780448_-|IS4-family-transposase
MPAKFHDPAALGGYYRLANEPDVTHAHIIRAAPRTWQRMRDETGVVLVLHDTTIGDYSGLSIEDLGQIGDGHGRGLYIHNALAVTPDRRVLGLAGQWLHKRRKVPKNETKAPRQRAPDRESRLWKRAVEQIPHAPAGRLWVDVADRGADVTEFLAHEHKAQRAYLVRSQHNRTVQQVDGSGAVAKARLHALIHTLMARACRTQEVQEAPGRGPRTAPLALAWADVTIVPPRQPRGDHDAPPLPVCAVRVWDVDPPAGQKGIEWILLTNVRVATESDAWARVDWYRARWVVEEYHKVMKTGVEIESLQFTTRGALEVTIGVLSVVAVSLLELRDLARDPQRASEPATHHVPRLWVVVLSAWRHARARGLDRARVRDGAGAAGRAPEPHTRRTTGGDRALARMDATPGHASRCGRRRPRVNGPKLKLLTTRLALHGLASVRPRP
>NZ_CP011271.1|WP_082840722.1|4786836_4788705_-|threonine--tRNA-ligase
MATEAELKAAGEKYIPKDYDPALYKLRHSLAHVLAQAVVERFPQAKPTIGPPNEYGFYYDFELDVNPTEGELEWIANRMKQIIKGRHVFKVREISAEEGRQIFKDNPYKLELIDGLTKGQDEYGNASADAPTITVYQQDTFSDLCRGPHVETTGDLDAKGFKIQQVTGSYWRGDSKNKALKRFHATAWANGDDLKAHLARLEEAAKRDHRKVGRELELFANEPVFGSGFPMLLPKGATVRRLLETFITDYERRAGYLHVFTPDIAKKELYKISGHWDHYKDSMFPPMDMGEGGNDDEELCLRPMCCPHHIQVYKSKARSYRDLPIRIAELGNMYRFERSGVVGGLSRVRCMTLNDAHLFVRPDQVKQEIAGVLSLMKKAYADLGITEYRFRLSKNGDPDGPATDKYVDNPAMWESSTKMLREVLTESGMPFFEAWNEAAFYGPKIDVQVKDVMGREETLSTIQADQHLPAKFELEYKDSDDTPKRPVMIHRGVISTMERMMSYLIELYAGAFPVWLAPVQVAIVPIGDRHFEFAQKLGEQLLDKDHRVDVDLSSKRMQAKIRDAQLQKIPYILVIGDKEMEANAVAVRLRSGEDLGAKPVAEFVAMLEKAIATRTLKLIPDA
>NZ_CP011271.1|WP_082840723.1|4788887_4789241_+|cupin-domain-containing-protein
MTPSAGNLFTNPPANPPADELFEVLTQRPGWKIERITSWGHATPQGEWFDQTTDEWVVLLAGAARLQIEGEPAPRELGAGDWVFLPARLRHRVEWTDETRPTIWLAFHIVPEVIKGL
>NZ_CP011271.1|WP_082840724.1|4789400_4794398_+|VWA-domain-containing-protein
MIHPLFAVFGPALAAGAAVAAVGVPLVVHLLFRKRYQIVPWAAIRFLMVAERRHKRRIDQWLLLALRTLAILLFLFAMIATTTWAEELWQKVRPGTTETIANVPRTHHVLVIDASLSMTARAEGDQTRFQRAIAQAENLVRSGNPGDGYTVFVLTTALQPLVPGPSNDPEKVVAELRKIKPTHGTADHTAALATVADVLTRSPRAYPRRQLTFFTDLQRASWANAVPRAENSTGEVWQRIVARSDVAIVDTAGHATENLAITDMVLVDPMPLVDQPVTVSVTVANLGRGERKGVRVELLLGRPSAGGEALVSVEQKLVEPIPPGGRQNVRFDLNHQHRFRSRGVHVLQAKIVETDDLPADDSRALAVEVRDGLHALLVDGRADPDVNRRGATYLLRALFPPGAKYTDTPNRPRVVTPGDFVDPSCDLTNVDCVFFCDVPNPTQEMAAKLEAVLRRGGTVVIGLGPNAASPTSRAKYNAELYKDGAGVLPGALGDVVAASGPDDPGFRLAADEDEYRKPPLAIFGADKLRAELVNEPFRGYVRIDAAADGRAHRLMTFARAGTGPAPMTTSAAKPDPALLEWSKHRGRAYVFTSSFNRDWNDWAAMQTYLVFWHEFLKHSAANPDRHTLRVGEAIEEFFPAAAAGLNAGLNGPDGLSATIPLLMQDEAGVATFANTAASGLYRVGLNGSRDRVFAVNVPEVVAGSPTESDLGQIDLREFRSFSAVQVVSDPAEVKPTSESGAVMTTAPKPHGPRISRAATLFAVLFLVTEIILAWRFGPSRSGGGTSPARSRIGRLLVLLGALVPLAVAAFILFSVAHADRTGNPLGFLPHGLRSSIENTAGVPVAGPGEGTRWRLEWFPALFKNSAADRRAVTGLACTCLLLTFGVYWIERRAAGGLARVTAPALLRAVTFLLALFVLLAQLRLAFDREGWPEIVILLDTSASMNTRDALKDPAVRAKAEELAGTTDLSQTSRLKLAQMLLTRKNADWLDKLLHEKQVKVHLYAIDTQLRPIGIVEEDGQLADAREALLKQEPTGDESKLGDGVEKILQTFRGSTLSAVIMFTDGVTTTGPDLPKAARTASLDGVPLFLIGTGDPWQSPDLALTDIQAEDVVGKGDQLVFKARLTAKGDVPPNPVTVLLQERLPNGKLEDRGRVTVTPDPNGNPVPVTVTHIPMEVGEKTFILSVPTVPGESNARNNKIERTVLVTESRRIRVLYVEGYPRYDFRFVKVMLERESDKSVGGKAVEVHVVLLDASKGWAETDRSAFRGDFPTRTELFGYDVVVLGDVDPKQVPRSAIALRDLADFVKEKGGGLLFLSGEHGTPNAYTDTPLAEVLPVVPGDQPVATRPPEEQPLVEGFRPRWTATGRQHPLFLLSPDEGESNRVWNQFQELFWFAKGYRPKPLTRVLATHPARRADGGAADENHALIVQQFVGNGPVLFFGFDDTWRWRFRNDEENFDRFWMQTMRVLSRSRVRRPEVRVEPKTEFRRDEKVTVQVRFPVEAPAPAGSAPVRVTMTRSPVLKDDGTPSPGPTETTTLTLPRTPGPTVLFETTLARAPEGEYRFELADPEVQGTRPFATARVLPPMNESERTELNRADLSAAAALSGGKFYTLADATDVFNDLKNLQRVPLNQPCPPVPLWNHPFLYVLLLSLLLGEWLLRKRERLL
>NZ_CP011271.1|WP_082840725.1|4794479_4798526_+|hypothetical-protein
MALLLRPPEERESLPDRLAELGRARKRVAFAAGALGFIGTVVGIAALSGLLDAAIHLSPFVRTLALVTLLAAGGIVWVRGISRAQRYRTDALAVALELEDQFPSLNDALASAISFLEPRGEDAPDDLPPTVPGVSNRLTASAVRVAERRAGRLPLDYIIPTGRCWWNAWACGAALAVALPLALFDTDRAAVAFARLADPFGAHPWPTKTRIEFLAPKEFPVRIPKGEAFELRFAVRGELVGPATVSVRVKDGGEFEDPFPLARNNDPQVPGAAVVTARFDPSRVSSTFEVQVTSNDAVTDWQTVTVVPPPRLVPLDGRPSPQFHVSPPAYTRLPAVELPAGATAIEIPTGTAVHFRAATDVKLSGAVLTFAGDKTAVTNAVPFAHLGQFDPIAAIGAQALANEMAADIPLTVSADGMRFSATFVPLLSGPYALKLTDDTGLTGTRVIKIDLTPDPVPKVTLNQPVTGRDPSYLTLAASVLVNALAEDPLYGVRGAYLEYRVGRDGPVRSIPLGAAGNQPIMALAGAAGGSAVVLSPPAASLEAFARVPIAAFLRDDGAPVREGDLIVLRAAAGDWDDVAVLKGRGRSIGEVEIRIAAPDAIDAWLQRELATIRPELVRIREQQRDAKQKTIEVLPLPGGTLAPADRDRLVGADLGQRQVTGKIADPAQGLRAKADLLRETVRANGLPKSNTTDRVEIVATELGRTADRDLGAAQQNLADALRLAGQLPKPGQEKELTDYLRKAGRSQKNIEDTATSLLDLLALWGGAGEIRSEARVQKDMILRQIVGNEHLKERVKEGKQNPAGDEQRELDRAALRADQSADQARELIGRAANLAAEKDKQAGDLRSQAALKEKEAAELKRQAAATENPVERSSLGAQADGVAASTVDMKAAADKAEAEAKALRKGIEAAGGQGLADGLRSAADLLRKNKQSGAETALRSAGGRLDALAEALAEKEVDAIPELAKPKVQRRAADQLDALAGNVDSLQKRVEAAARLPDPTQRAETLKILGQEQDKLVERGREMLQKLTAEKAEDAARDLRSALDRMESARDDLEKGQPNTRSQREAVERLDAARDKLDLAAAQGGRQLSDEKRRKLADQVRALLEKQRAAVTEATRIHGEVAKQKGWDKLLLTSYSDIDTVREKDIAIEVRKLAEADFAPLPVFARLLNDSAKAIDTAREKIKTRCDDADLAAAFDADLEALGDRKVMRPMELALRRLEQLADALKPDDKKPPAKNGNAPENPPKAPNPPANPNGGGEPDVVPPLAQLKVLRALQAELNERTAQFAKDHPEPDKLTDSEKEELGELEQAQREVTELFEQMAKLFPSAEKETDKSEKAGGGDAKEKQGP
>NZ_CP011271.1|WP_082840726.1|4798566_4799424_+|hypothetical-protein
MNRISFFAMFAVTVACTNARAAAERPVAPPPREIRPDGTRDPVPQSEPPAPGENPAVTVKRIIENSKDVGDKLAKTDTGTDTRKKQNKILSDIDALINQQENPPPPQPDQNKDKDKNQDKDKSKDKDKSDKKDPMMDPGMAMKNDMPMSGMNMGDPPPMGGMGESQPMGRKPRMGDPMNDTKKEQNSGAKEQNKPESEPKKGGQEPKGTPGKTGGNPMGTMKPGKPSMPFEEDVAKDVWGHLPDKLRQQMSQYYKEDFTPKYAELLRLYYSSLSEKGTKPGEPRK
>NZ_CP011271.1|WP_052555030.1|4799504_4800653_+|twin-arginine-translocation-signal-domain-containing-protein
MRNPLRSVSRRDFLRTTAVGGSVGALHLAGFAQQGGPRADEQTAPRSDTGAEFITPDTQSAVDRGLGLLAQSQSADGSFGDRISGATAGITGLSGLALLGAGNQPGRGKYGRNASRVVDYVTGLVTGTNPGFLSDNQFGRMGNQPSAMYSHGFAGLFLAEVCGMLPDVQRQKKVRAVLEKATAFAVAAQNGEGGWRYEPNAPFADVSVTVAMMMALRAARNAGVFVRKDVVRRGAKYIRECQLADGGFSYFKGNGPSAFARTAAAVVGLYSASIPEDEKVNNGAIERGLRYLQQFMPNRQFNQRELPPAHYYYGQYYAALAMWSAGGDYWRTWFPAIRDELLGRARASGGTWTDTYHGPAYATAMSLIVLQLPNNYLPILQK
>NZ_CP011271.1|WP_082840727.1|4800842_4802519_+|hypothetical-protein
MTAWATIRRFGAAGALVLSAFVFTSPPASGTPEPKPVRPAKPTPAQLREIAEKAEKNGDWEAAFNAYCHLFVADRSSPELRDKLNVALRYTQQLRRYRDPSFQQFVNGVQLDSGLDLFDEVFQKLPVVYADREKATVQNLWAFAIEELDRALGNVAFRQAFLNAPRIDKVDQFRSTLRQQWAKRSIADHKEARSGLRRLIAAAQEHFTVRVPAAFAIEAACGACSGLDEYTVFLAPSAGSDASQIPDLSAAGLYLGIEKNALVIDGIVPNSWVALNYPQLRRGDRVTRLNNRTMDAAGLSGAINALRNPTDGAHQLDIKGAGDDAKIEVRIPVTIPSVYGTGMIPSKPVGYVRIGNFQTSTPQELDEALAELKSKGARAVVIDLRGNHGGSFLASVETARRLLPAGLIVTTQGQVSDVANQVFSSASGMSAHDIPIVILIDAETASAAEVLAAALKDNNRATLVGVPSFGKGTVQCPVKLVTLDDLDPATGKKVSKTGTVRVTIAKLVAPSGPISGGGISPHFLESDTTLQLEIAADKAQELATGRMSQPIPAPPLIP
>NZ_CP011271.1|WP_082840728.1|4802594_4803074_+|hypothetical-protein
MVERWWATLTETEQRELSELRDSRREEHFFTPQSAFIDLPDAWENLPTVTGGRFVPHDDSARMADWIDDWLEYLSGHEEVVLLSRAVVVFRTYHMCQIEPAARAVTACGLLPASFCCPVARPTCPMQRVQAIAPNQSFHLAPAAAGGWWVIAPGVRTRN
>NZ_CP011271.1|WP_082840729.1|4803168_4804044_+|carboxylating-nicotinate-nucleotide-diphosphorylase
MSSSSLTAAEADAADALIRLALAEDFGTTGDRTSLATIPEATRARAAFVARTTGVVAGLPVADRVCRTVSADLTFTPAVPDGTATGRGTVLATVSGPLQAILAAERTALNFLQRLSGVASLTRRFVDAAHSSTAKVLDTRKTTPGWRLLEKYAVRAGGGTNHRIGLYDGILIKDNHIAGLNGDVRKSVEAARTYPGNAGLPVEVEVDTLEQLEHALAVKADIVLLDNMSLDQLRAAVNRRNEVSPATLLEASGNVNLTTIRDIAATGVDRISVGAVTHSAPALDIGLDYAA
>NZ_CP011271.1|WP_082840730.1|4804040_4804838_+|biotin--[acetyl-CoA-carboxylase]-ligase
MSDSFTPRETWHFDTELIGRRVLVYDSVDSTLSLGSTLAASEEDTDGLVLIADHQSAGRGQYGRTWTSRPGSSLLMSVIVRPPTELRRPVILTAWVAVAIADAVKTLTGAQARLKWPNDLLVTEKKICGILIEQSSSAGALTTIAGTGLNLTQTAEEFAQANLPSATSLGIISGGAIDTRAAAGVVIRKLDREYSRLCAGESSAVETEWKRRTGLLGRQVVIEHLGGASTTGRLRDMSFGGLELEDPAGFVSVVTPESVAHVRAV

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Crispr_ID: NZ_CP011271_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_13

5194645-5194745

Orphan

Consensus_repeat	Method
ACATCCACCGCCCTTGCGGGCGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_13

>merge|NZ_CP011271|13|5194645-5194745|CRISPRCasFinder
ACATCCACCGCCCTTGCGGGCGGGGCTCGCCCGGCGTTGTTGGCGAACCGCGAGTGACAACGAGTGAGTGCAAGCTACACCCACCGCCCTTGCGGGCGGGG

>NZ_CP011271|13|13|5194645-5194745|CRISPRCasFinder
ACATCCACCGCCCTTGCGGGCGGGG	CTCGCCCGGCGTTGTTGGCGAACCGCGAGTGACAACGAGTGAGTGCAAGCT
ACACCCACCGCCCTTGCGGGCGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_082840933.1\|5203030_5204584_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237057
NZ_CP011271.1\|WP_082840930.1\|5198297_5199362_+\|histidinol-phosphate-transaminase	unknown	unknown	gnl\|CDD\|235440
NZ_CP011271.1\|WP_052560918.1\|5208015_5208750_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_162271797.1\|5205221_5207171_-\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP011271.1\|WP_052560902.1\|5187062_5189582_+\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP011271.1\|WP_082840923.1\|5183313_5184075_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|369777
NZ_CP011271.1\|WP_082840925.1\|5189584_5190664_-\|tryptophan--tRNA-ligase	unknown	unknown	gnl\|CDD\|234866
NZ_CP011271.1\|WP_082840926.1\|5190812_5191610_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082840929.1\|5196714_5198139_+\|histidinol-dehydrogenase	unknown	unknown	gnl\|CDD\|376389
NZ_CP011271.1\|WP_082840928.1\|5193560_5194469_-\|ThuA-domain-containing-protein	unknown	unknown	gnl\|CDD\|377643
NZ_CP011271.1\|WP_052560911.1\|5199409_5199997_+\|imidazoleglycerol-phosphate-dehydratase-HisB	unknown	unknown	gnl\|CDD\|234873
NZ_CP011271.1\|WP_052560919.1\|5208760_5209942_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082840932.1\|5201228_5202638_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052560908.1\|5194802_5196101_-\|PP2C-family-protein-serine/threonine-phosphatase	unknown	unknown	gnl\|CDD\|225118
NZ_CP011271.1\|WP_082840931.1\|5200258_5201218_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_162271795.1\|5182745_5183273_+\|DUF4240-domain-containing-protein	unknown	unknown	gnl\|CDD\|379426
NZ_CP011271.1\|WP_052560905.1\|5191790_5192522_-\|ribonuclease-PH	unknown	unknown	gnl\|CDD\|178914
NZ_CP011271.1\|WP_082840921.1\|5182162_5182711_+\|DUF4240-domain-containing-protein	unknown	unknown	gnl\|CDD\|379426
NZ_CP011271.1\|WP_082840927.1\|5192811_5193447_-\|DUF479-domain-containing-protein	unknown	unknown	gnl\|CDD\|225666
NZ_CP011271.1\|WP_162271796.1\|5184085_5186674_-\|protein-kinase	unknown	unknown	gnl\|CDD\|270916

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_082840933.1\|5203030_5204584_+\|hypothetical-protein	gnl\|CDD\|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	1.30978e-05
NZ_CP011271.1\|WP_082840930.1\|5198297_5199362_+\|histidinol-phosphate-transaminase	gnl\|CDD\|235440	PRK05387, PRK05387, histidinol-phosphate aminotransferase; Provisional.	1.80171e-106
NZ_CP011271.1\|WP_162271795.1\|5182745_5183273_+\|DUF4240-domain-containing-protein	gnl\|CDD\|379426	pfam14024, DUF4240, Protein of unknown function (DUF4240). This presumed domain is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 169 and 263 amino acids in length. This domain is often associated with the WGR domain pfam05406.	1.16928e-30
NZ_CP011271.1\|WP_082840923.1\|5183313_5184075_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	4.19808e-20
NZ_CP011271.1\|WP_082840925.1\|5189584_5190664_-\|tryptophan--tRNA-ligase	gnl\|CDD\|234866	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed.	1.5903e-160
NZ_CP011271.1\|WP_082840929.1\|5196714_5198139_+\|histidinol-dehydrogenase	gnl\|CDD\|376389	pfam00815, Histidinol_dh, Histidinol dehydrogenase.	0
NZ_CP011271.1\|WP_082840928.1\|5193560_5194469_-\|ThuA-domain-containing-protein	gnl\|CDD\|377643	pfam06283, ThuA, Trehalose utilisation. This family consists of several bacterial ThuA like proteins. ThuA appears to be involved in utilisation of trehalose. The thuA and thuB genes form part of the trehalose/sucrose transport operon thuEFGKAB, which is located on the pSymB megaplasmid. The thuA and thuB genes are induced in vitro by trehalose but not by sucrose and the extent of its induction depends on the concentration of trehalose available in the medium.	1.42907e-55
NZ_CP011271.1\|WP_052560911.1\|5199409_5199997_+\|imidazoleglycerol-phosphate-dehydratase-HisB	gnl\|CDD\|234873	PRK00951, hisB, imidazoleglycerol-phosphate dehydratase HisB.	1.28859e-122
NZ_CP011271.1\|WP_162271797.1\|5205221_5207171_-\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	7.16643e-47
NZ_CP011271.1\|WP_052560908.1\|5194802_5196101_-\|PP2C-family-protein-serine/threonine-phosphatase	gnl\|CDD\|225118	COG2208, RsbU, Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription].	2.18943e-47
NZ_CP011271.1\|WP_052560902.1\|5187062_5189582_+\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	9.19757e-105
NZ_CP011271.1\|WP_052560905.1\|5191790_5192522_-\|ribonuclease-PH	gnl\|CDD\|178914	PRK00173, rph, ribonuclease PH; Reviewed.	2.73118e-138
NZ_CP011271.1\|WP_082840921.1\|5182162_5182711_+\|DUF4240-domain-containing-protein	gnl\|CDD\|379426	pfam14024, DUF4240, Protein of unknown function (DUF4240). This presumed domain is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 169 and 263 amino acids in length. This domain is often associated with the WGR domain pfam05406.	6.79796e-39
NZ_CP011271.1\|WP_082840927.1\|5192811_5193447_-\|DUF479-domain-containing-protein	gnl\|CDD\|225666	COG3124, COG3124, Uncharacterized protein conserved in bacteria [Function unknown].	1.57586e-34
NZ_CP011271.1\|WP_162271796.1\|5184085_5186674_-\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.83391e-103

>NZ_CP011271.1|WP_082840928.1|5193560_5194469_-|ThuA-domain-containing-protein
MKKFTLLLAVATLVAFGPVARATAEDTKKATGNKRLLLVTHCGGFPHSSVYTAEEVLKAIGPKNGFDVTCYRFTEDPDQIVKDKGVERTALEAYSDKFRGATKQPVGKEHCGRINKETLKNFDVVLFFTTGNPVNKQELADLREWVKAGGALAGTHCATDTLYGESVYGDLIGAYFQGHPPGLQKIKVKVEDAKHPAAAGFKDGMDYQDEMYIFKPAPYSREKLHIIFSIEADSFNPGKNLVRADNDYAISWCREEGKGKVFYTSFGHDPKVWKDEKFQHHLFGGLKWAAGELKGDATPSKK
>NZ_CP011271.1|WP_082840927.1|5192811_5193447_-|DUF479-domain-containing-protein
MPVPTSRTEPLNFLAHLHLADGDPGDMAGGVAADFVRNPDLPSLTPDVLRGVMLHRLIDGFTDRHPLTLRSISRVSREFGWFGGILIDIYYDHILAREWTRYSTETLPSFAARSYRVLEDHLVGLPGDASDFMRRFVDEDRLNRYATLDGIEDTLARVSKVIAKRIPNRAMWLPDAMPLLISRDADLATDFHGFYPELMAFATEHKINRPK
>NZ_CP011271.1|WP_052560905.1|5191790_5192522_-|ribonuclease-PH
MPRPNDRAPSALRELTFLRGFTRPAPGSVLVKMGRTTVLCTCCVEPKVPDFLVGKGKGWLTAEYGMLPGSTNTRKPRDKAGKVDGRSVEIQRLIGRSLRAVVNLDKLGERTLWIDCDVLEADGGTRTASITGAFVAAVDAVNSIKALLTVPVSEVLTDSVAAVSVGLVDGEERLDLEYVEDRDADVDMNLVMTGSGKIIEVQGSGEEATFSRKQLDALVDLGEAGIRTITAEQKKVLGTAWPF
>NZ_CP011271.1|WP_082840926.1|5190812_5191610_+|hypothetical-protein
MDGPSPIPDPHAPAGFVALNDPRRTEFLVEALKVALHSAGEHRLFQSGKLPGLFPARTGLAAEAALQALREGLLETVRTEAKGKLITEWVCATPKAVGYVHEHDSPRSILRELKDVLQATRTGVPAFMEEAKAELAALSANFEKRAAEMLGRLDDLAKRCEAALRRAETSGPVVTESVGRVVPWAVDALEYLDRRTQSGATGDCPLPELFHAVCVRCPELTLPAFHDGVKRLHDVRAVRLTPTSAIPEPEYAVVVEGQLMYAVGR
>NZ_CP011271.1|WP_082840925.1|5189584_5190664_-|tryptophan--tRNA-ligase
MSVTVRPRILSGVQPSGKLHLGNYFGAIKQHIERQDSGECLYFIADYHSLTSLRGAEEKEAGLAAKNKSIVARPARQILADNVRDVALDYLALGLDPAKASFFRQSDVPEVCELAWIFSTVSGMGLLERAHSYKDKVARGLTASVGLFTYPILMAADILIYRSHLVPVGKDQEQHLEMTRDIAGSFNHAFGEVFPLPDGVYSETAVVPGTDGQKMAKSYGNTIEIFAEGKALKNAVMSVVTDSTPVEEPKNPEKCNAFALYKLFSTAAEQAEMADLYRNPMKGAELRGGRPFGYGDAKTQLLAKIDAYFAAARERRKQLARDPGFVEEVLVAGAKRARALAQITLQTVRKAVGIHPNPV
>NZ_CP011271.1|WP_052560902.1|5187062_5189582_+|protein-kinase
MKLSADQFATVVRNLPLPNDQAAAAAEALAQPATDELPGELIRREILTEYQARMILSGHADELTIGRYTILDELGEGGMGQVLKARDTAMDRVVAVKLIRDDRFGSESAVRRFEQEVRATARLAHPNIVRAYDTGVFNDRHFLVTELIAGSDLGHELARRGSFPAGEACHYAHQTALGLQHAHEHGLIHRDIKPSNLLFSAAERTVKIADFGLAYLGDSGAGRLTAAGAVMGTPDYIAPEQASSASAADIRSDLYSLGCTLYQFLTGRVPFPADSALAKLVAHASEAPPPLDTVCPGLAPGLAAVVQKMMAKSPNERYQSPLEVAEALAPFCDPRNARIATNSARAIAVPPHSTLNNAADLTAHSAPHPEPSRREPKARSPRRRTVGLVAGAGVLVAVIIALVFISRPTPSESPDVRPVQITVKLDDWPSAREPGAVIYLSGASLPTSESEKARTSDDLKRPLELAPGTYGLTLRIGGEIIERREFNVTSESAHRAIALGPIVPEVVAATITNGREVKRWEALGPVSDLVFLPDGKKFVSMERPTGVFRRPQAHELTISGALYATETNEIFSRWDTVGSGRVALFPKAGAVVGCQFPDPALKSDAYRWWAVPLSSGETPTNDGSVVAGASTQKHRTSLLTASADGTRLLLSFVTQPGDKAVGTVQLCPVTFTDARTIAVGEPKLFPGDTACFDPSGHRLLVANGTALALYDQDTGKPMAPEFTGATASIQDVAVAPNGKYLAAGCADGAVYFWRTGTKEPIAVGRGHKGKINVLKFTPDGARVVSAGEDGTVRVWLTETGKEIAQFKHDGSVNALAISPEGKRVLTGSADATIRLWQLP
>NZ_CP011271.1|WP_162271796.1|5184085_5186674_-|protein-kinase
MPDEPGSALQVQALPSGVQTRDSREQAAASAVGVELVTPPPAARPSNPPSGGTPFPSSHVFGFASTNPDPNHRSATPPPGPISGDAEDPGIAPHTEVRGYTIERELGRGGMGTVYLATQLSLDRPVALKVMSKRWATDPVFVARFTREAFAAAQLSHPNIVQIHDIGEVDGARFFSMEYVRGKSLADLLKVQGKLDPETAVGYILQAARGLKHAHDRGMIHRDVKPDNLLLDVQGLVKVADLGLVKTPAVSRADDRLADPSARSGLLSLPPDMTGARIALGTPAYMSPEQCRDAATVDHRADIYSLGCTLYVLVTGRPPFDGTTAVELMSKHAYDPLVPPEQIVARVPKEVSAVIQRMMAKSRDDRYQDMSEVIRTLEAWLGVYHAGTFSPHEEQISRLETAVLRFNTCGTAVLRGRLISGFFGTVALMAVLLAFFGKIGWAFGIFGLALETTLAYFVLDGITRKGHLFSCTRRFISGLGRGDWIVGLSGFAMFCVLLALLKVFWMWIGFGLIGIGIAFALRYGMDRALVEERREIIEGCERQLRRMRARGLDEEALRQFVAKFAGRDWEEFFETLFGYEAKLAARTVLLRGGAAGVRETHAAWREPIIATMERIEKSRKDSRERKLLLAVERANLLAAGANAQTAEDQARAAADAMVRAADEIRRAETAHAPGGATAHAPTSVRTLFRAAEQPDDFVFVPTRKRDPLGTIISLFVGPHVRTIGAALLLAACALWAHQNGLVPGAELRAQATQAMESQDLSALQQPVALDATRATKPLVFPGVPAPVLGWVDSFNVGLAGLMLLASLFFRGNLMSVLVLIGAAVAAIGHQFGIHTVEPFRDYHVSLMLGSLLTLVGFRLGTR
>NZ_CP011271.1|WP_082840923.1|5183313_5184075_+|class-I-SAM-dependent-methyltransferase
MSAFKDHFSGHASDYRTFRPTYPPELFTFLASVAPARDLVWDCGTGNGQAAVILAEHFNRVFATDASAEQVKNATPHPNVEYAVAPAEQCPLPNASANLVTVAQALHWFDIDRFFAEVRRVCKPGGVVAVWSYDLHSVNADVDPVLDRLQSEFVGPYWPPERALVDAGYRTIPFPFTEIPSPRLEMTARWDLPTLVGYMNTWSATKRFEKTNGFNPLDRLSEAFTAAWGEPATVRTVRWKLATRVGRVENPKT
>NZ_CP011271.1|WP_162271795.1|5182745_5183273_+|DUF4240-domain-containing-protein
MDWKPFWKVIEDAYRPDPIDHFEALKERLGALKWFEIIEFQARFDEAVSSANLIDLWGAACLINGGCSDDGFRDFRVWLVGRGRRAYEHALRDPDSLTDILDGDPVDGFGLDAAALRVYEEKTGMSDFYTRLDRAEVDSPPPPPEGADWDFEDESEMRKRFPKLCHLYLIPERDE
>NZ_CP011271.1|WP_082840921.1|5182162_5182711_+|DUF4240-domain-containing-protein
MTLDEFWDHIQKSKRKDPDAHAERLEQRLTKLPPNEILDFNHWWELMMGEAYNWNLWGAAYLINGGCSDDGFEYFCRWLVLRGRDVFQTAVTTPDTLADVVDPDDGDVECECYPAMLAWFAATKTKRDEAGYDAYNAAVKARHPNGSRYPALGAGWDFDDDAEMRKRLPRLSALYMDGGAGE
>NZ_CP011271.1|WP_052560908.1|5194802_5196101_-|PP2C-family-protein-serine/threonine-phosphatase
MTVAPDFFDTEPRNWRARLAVSVEVMRELSRSTDPQEMYAVFTRRISQLFPLSRHLTIARRGLHDPEYRVVRYSMWKESVNPWKESHRLPVHHGGILAQLLYGDQPRVIDNLNIDPDDPAAEYLVGQRSLLAIPHFEHGVASSMVVITRDDTATFPRERVADLVLLSNLFARATQTVVLSQAVKEAFDGLDYELRSIAEIQKSLLPAEKPKVPNLDVAVHYQTAKRAGGDYYDFFPLPNDRLGVLIADASGHGAPAAVLMAVAHSIAHTRPEPPQSPGEFLTYMNAHLTRRYTRPTGSFMTAFYAVFDPTNGTLSYASAGHNPPRLLRCADGFKLALNRAQKLPLGIKPDEVYLEQTLPLLPGDQVVLFTDGVIEAVNTEGDVFGSARIDEELETCLPSAGALLRAILASHSLFTAGTTPADDRTLVVVKRT
>NZ_CP011271.1|WP_082840929.1|5196714_5198139_+|histidinol-dehydrogenase
MPALKLRRIDLTANNAAAQIAKLRDQFRTDTEVVSAASKKKTQAVFGEALPPARAVERICNDVREKGLAAALNYTELFDGVKLKPDQLRVKPAELAEAHANVGDDFLEVIRQIRYNVMQFQSGLLQRDAVMPVSGKHELQVRYRALNRVGVYCPGGAAAYPSTLLMTVCPAQVAGCEQIIVCMPPNATGAYNREMLATCHELGITEVYRLGGAQAIAAMAYGVEGLKPVDMIVGPGNQYVALAKKHVFGQVAIDCIAGPSEIVVLADDSAHPDYVALDLLAQAEHSPGVAVLVTWYEPLMNEIQDALAKRLAKLSRADLAKDSLERFGAIVLAPNKAAAVDCVNAIAPEHLHIQTRDPDAILDDIESAGAVFLGPFTPVAVGDYAAGPSHVLPTGGTARFASGLNTNDFRKRTSILRFTRNGLKDIASDVIFLANKEGLTAHAASVELRANDNGPAARPKPKPEKVPAAAPAKK
>NZ_CP011271.1|WP_082840930.1|5198297_5199362_+|histidinol-phosphate-transaminase
MTVRSNIRAMAGYVPGEQLNDPDIIKLNTNENPYPPSPRVFEAIHAALTSNSLRKYPQPLGDTFRKAAGRVLNVSPDSILIGNGSDDILTILTRAFVPEGGLMASATPSYILYRSLAEIQGARFEAHRFTDSWAIAESWPRGANLTFLPNPNSPSGTVVDPKSIVQLAQALAPAPLVLDEAYADFTTWTGLELLASTPNLIITRTLSKSYSLAGIRFGFAIAAPELVRELVKVKDSYNCDVLSLAAATAAIEDQDYFREVRAKIIATRTRMTQELTAQGFDVTPSHSNFVWCRRPDRPVKPIYEELKRRKILVRYMSYPAGPLSAPEGPYDGLRISVGTDAEIDKLLHELKAIL
>NZ_CP011271.1|WP_052560911.1|5199409_5199997_+|imidazoleglycerol-phosphate-dehydratase-HisB
MPRTARIERKTAETEIDLTLNLDGTGASKLATGVGFFDHMLTHIAKHGLFDLTVTCKGDTHIDAHHTVEDVGICFGKALVQALGDKAGIRRFGDCTLPMDDTLATAAVDLSGRPYLVWRADVPLETLGTFSSQLAEEFWRAASSTGLFNLHVVLHHGRNTHHIVEAIFKACARALRAAVEPDPRASGVPSTKGVL
>NZ_CP011271.1|WP_082840931.1|5200258_5201218_+|hypothetical-protein
MEEEAKAKKPRAPRTAKAPQQPQSVDALVQHALKLAATNPKAKWTGATSAALFNTKEANSAAAIERCRDASRPLLKQHKDGATLTGAGFEEVAAALSEEQVTPVAKSVANGLPVGERADFLQGVIGRTPLAAAELTPLLEEAIAAEKAARQAREEEAAKRRAAEEASLQALKRAQKLIAERQQARVAELLRLLEIEGQKPPEPTAERPPAPTLEVAPAVPNNSEDKDFRRDVAAQLASSWRATWELNKPDAREFLESAMWNISGFKLVGEVGQRVAYSGRVHESVAGVFSGDQVKVARPGWVLDEDAGEFVVLKAVVEK
>NZ_CP011271.1|WP_082840932.1|5201228_5202638_+|hypothetical-protein
MADRVFCIDFGSAYTKVALRRDPTADSELLSWPNIDFCVPSTIAVDRRGTKAKLAFGDEAADQQSGGGIDVHRNWKRSVFLAPAAARPTQSPLEALLQSDDLLALATRYGVPHGQIGYLQQMVGSAKALIAGPGGRIVSAESQQQTIATALAAHFFHWLRQRTMEACAKLPTTGLKFEDIPVRVAVPAFARGGDDPHPGRKLVLDALDKAGWPLHPDQPAVAEPYSNAIGVLTKGANVLGRNGRLNFSDMFSKGPLITVLKDAAHYPSYRALVIDVGAFTTDFTALTFKPTGEPVLTPDSGFELLEKSVPFGVSDLDEEMRLTLKVSEWPVKPTWTDWAKVQQSVYSEGKGYRAPGLGKVVGGPADSEAVQACLRTFTQRIVDEATAFCEPLEPAFTQELILTGGGSNIPVVREALQTAAKAGGNTFVKTHAPDLKRVKGVPVDKLDEHFARGGSALGGASIYFEKGYY
>NZ_CP011271.1|WP_082840933.1|5203030_5204584_+|hypothetical-protein
MASPPVTFPCPFCSRRMGVHTELLGRQVRCPHCKRVVIAPAAAGTPSASPPPEPEIRPFNIPQKEGADSILSESDESDDEVFISPANTPTRPILFSPSQQSSEPESEPAPTPGVNESVGLNLFPESSDSLPDPVPQTLVTGPAPGHHASAFSAPPVPEQKPEPPSPLTSLNPDPEREDTPPNPPDLPPRPDEANPFTGFEPDPLPLPFVKAPKASELLSAPDAPSPEPAPSKKQLLDETPTEDKEKPARAERSRPAPVAASSRAKTTVLVLLAGYALVVTVLAVYGLFFKSRGVPETGHPLSTIPDTFGEFDPVSRKKVTKLDFPVDGELPTAQRAQLGGKITIGQLEVEPIRVQKRPLQMILEGTDEKDKQTLRAGTALVMTIAIKNLSSDLPIYPMDPAFLRRATKDDQPITRLVIGHKVFAGGEIEWPLPSRFKKKFEVQQGNDAKILEPRHSQEYIVFTEANPELVKAAESTREALQWRIQVRRGLIDYKGKEVPVTAVIGVDFKASDIRGMD
>NZ_CP011271.1|WP_162271797.1|5205221_5207171_-|protein-kinase
MPLVSAPDCGTHSVYTKSAGYAPLPGYVLLEPLGRGGFGEVWKCEAPGGLHKAIKFVTGDSDGANNDSAQLRQELEAFQQVKAIRHPFLLSLERVELVGAELVMVMELADKQLGDRFEECRGQGLPGIPRQELLGYLREAAEALDVIGAKYGLQHLDVKPANLFLTAGHVQVGDYGLVSKLDTGKSRQENRGLTPRYAAPEVLCGQVHTRSDQYSLALVYYELLTGTFPFNGRSVQQMMLQHMTAAPDLNGLAPPDRAAVATALAKKPDDRFASCADFINALCGGTSRSVAALAASLLTPSPRGSGSITAPPSSAPTRGVSAANEPTLRNVPHFVTPAATPAPQPVPPKRVTYTQPAPAAATVERAATRTPQPKPAGVCLEQILSVVPIAWLQGKFAQAPGRPPTHLVNAVLRAAETEAGINSAMGAVNRDRDGTWGCRFLSSIDPRVAQVKLDLLWEEGGVTMDSRTEGRVEFRKLAPVPAPTGWFSSKPKAPDSGLQVIVELPDPGAGTGEVVVTGTFFGNPPSEFAKSGEKTIVKLIEGIRRTLNDTQDRRKHPRVPATFPLTLYPLQSDGQVEPPMKGFCRDVSAGGMALFCATEPTTKYMFVEFEGVPGTTGLAVLLQTIASEWQHDEVLVTGKYRLEFGPTDG
>NZ_CP011271.1|WP_052560918.1|5208015_5208750_+|hypothetical-protein
MGRGADPFAAVPHPIKLSASVIIQNTHRQFNWALDGRVKPVVLPSAREIDFGRLWNAPSLERSVPLHLAPGIEVRAAKLVGEGYGLVPEIRRGDKTSELVVRLPSLGPPSRYKCEVQIIPVTRTGEPIDLPPIPVNWEVLHEVQPDTTTVDFGVLTVGAVSEKTLTLSSLNGKPFRVTRCQIDAPGGAVAAPEPATSLPVLVSRRIDRTGDQTGEVHIEGVTDTGASFTIKCRTHYFGVNPASP
>NZ_CP011271.1|WP_052560919.1|5208760_5209942_+|hypothetical-protein
MSANVAQIGAVFFAALCFITFSGRAIAQSPEDALRQQVTAAWEKRQAAVKTMRVTFSSKTTTPKGVLTGFAFPKPRAPGEQGERKPSPPSDAIKTGTGELVLDGGKTRIVNHAPIWDFDKDDFVFCRHESSFDGQTLTLFQYPEPGWPQALIEKAERNQNTDDVLVAPLFGAVRGLHPELASSLCLSAYTQARRVGSEQERSLIELTRPRNETRGEWKLWVDPSRDYAIVRMEAHDRDGKLVTKFTVTQSALPAATTIWLPQRWTAALFRNGNLFKQIEVTTHAREVNAELSEVEFKPVLPVGTRVQEKIGNEMKDYIIRDGGQTREIQRDERKASYEDLVNSQTGDLAPRSPSTPGRWWLIGSGSVIGAVSFWVLVRHRIGRTSSTNPSTNT

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Crispr_ID: NZ_CP011271_14

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_14

5529625-5529729

Orphan

Consensus_repeat	Method
CCTCGCGTCCGAGACCACGATGAAGCGACTCAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_14

>merge|NZ_CP011271|14|5529625-5529729|CRISPRCasFinder
CCTCGCGTCCGAGACCACGATGAAGCGACTCACTGATGATCCGGATCAGGTGTTCGGATCCGAACACCTGAACCTCGCGTCCGAGACCACGATGAAGCGACTCAC

>NZ_CP011271|14|14|5529625-5529729|CRISPRCasFinder
CCTCGCGTCCGAGACCACGATGAAGCGACTCAC	TGATGATCCGGATCAGGTGTTCGGATCCGAACACCTGAA
CCTCGCGTCCGAGACCACGATGAAGCGACTCAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_082841093.1\|5537530_5538211_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_162271812.1\|5530894_5532199_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227697
NZ_CP011271.1\|WP_082841083.1\|5528133_5529399_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|316042
NZ_CP011271.1\|WP_082841090.1\|5536656_5536872_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_157470465.1\|5520462_5520705_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841087.1\|5533780_5534641_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082843375.1\|5516521_5516647_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226350
NZ_CP011271.1\|WP_157469726.1\|5536868_5537231_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841088.1\|5534712_5535219_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082843376.1\|5517558_5520186_-\|magnesium-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319772
NZ_CP011271.1\|WP_082841086.1\|5532272_5533781_+\|phage-portal-protein	unknown	unknown	gnl\|CDD\|377468
NZ_CP011271.1\|WP_082841082.1\|5527786_5528137_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841078.1\|5521144_5522302_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841081.1\|5527237_5527660_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_162271811.1\|5530464_5530923_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841092.1\|5537234_5537531_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841080.1\|5525687_5526881_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|274042
NZ_CP011271.1\|WP_157469724.1\|5522664_5525292_-\|phenylalanine--tRNA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234804
NZ_CP011271.1\|WP_052552385.1\|5520238_5520466_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841089.1\|5535294_5536557_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_162271812.1\|5530894_5532199_+\|hypothetical-protein	gnl\|CDD\|227697	COG5410, COG5410, Uncharacterized protein conserved in bacteria [Function unknown].	1.50385e-29
NZ_CP011271.1\|WP_082841083.1\|5528133_5529399_+\|AAA-family-ATPase	gnl\|CDD\|316042	pfam13481, AAA_25, AAA domain. This AAA domain is found in a wide variety of presumed DNA repair proteins.	2.60569e-23
NZ_CP011271.1\|WP_082843375.1\|5516521_5516647_-\|hypothetical-protein	gnl\|CDD\|226350	COG3829, RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms].	0.000472806
NZ_CP011271.1\|WP_082841080.1\|5525687_5526881_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|274042	TIGR02224, Tyrosine_recombinase_XerC, tyrosine recombinase XerC. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerC, one of two closely related chromosomal proteins along with XerD (TIGR02225). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and homologs of XerC on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerC, as some apparent XerC examples score in the gray zone between trusted (450) and noise (410) cutoffs, along with some XerD examples. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	2.95965e-17
NZ_CP011271.1\|WP_157469724.1\|5522664_5525292_-\|phenylalanine--tRNA-ligase-subunit-beta	gnl\|CDD\|234804	PRK00629, pheT, phenylalanyl-tRNA synthetase subunit beta; Reviewed.	0
NZ_CP011271.1\|WP_082843376.1\|5517558_5520186_-\|magnesium-translocating-P-type-ATPase	gnl\|CDD\|319772	cd02077, P-type_ATPase_Mg, magnesium transporting ATPase (MgtA), similar to Escherichia coli MgtA and Salmonella typhimurium MgtA. MgtA is a membrane protein which actively transports Mg(2+) into the cytosol with its electro-chemical gradient rather than against the gradient as other cation transporters do. It may act both as a transporter and as a sensor for Mg(2+). In Salmonella typhimurium and Escherichia coli, the two-component system PhoQ/PhoP regulates the transcription of the mgtA gene by sensing Mg(2+) concentrations in the periplasm. MgtA is activated by cardiolipin and it highly sensitive to free magnesium in vitro. It consists of a transmembrane domain and three cytosolic domains: nucleotide-binding domain, phosphorylation domain and actuator domain, and belongs to the P-type ATPase type III subfamily. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP011271.1\|WP_082841086.1\|5532272_5533781_+\|phage-portal-protein	gnl\|CDD\|377468	pfam05136, Phage_portal_2, Phage portal protein, lambda family. This protein forms a hole, or portal, that enables DNA passage during packaging and ejection. It also forms the junction between the phage capsid and the tail proteins.	1.54944e-22

>NZ_CP011271.1|WP_082841083.1|5528133_5529399_+|AAA-family-ATPase
MNIRDEVSARLAQPRPEVKLHRPDEPAAVPKLALNVIPFAGRRIQTMQYLVPGRIPLGKLILCGARGGSGKSTLWRAIAADISAGRCALGLSYPDPVRAKVLFFASEDGADDTALPGLLAAQADLLRVAFVDGVERGPCKSEFMLTPDHIRVLRERLEQSPDIKLVIFDPIASYVGRAKVDDHRASELRLVLDPLSELAESKGVTIVMIAHLNKSTGDAVDRFAGSAAYRDTVRAAYAVSEDPEDSSRRLFMPVKENLPGFDRSTIPFSLVPLTDAEMDAFFAAPECHHLNATDRQTLRSQLRRVKFDPPRTVDPNQAMKPPTRKESGTGSDNGQTKLDRCKEWLRNFLQKYAYPSSEIAEAGRAEGFTFDNLKFAKARLKEEGVISHSNSVYAPGAWWSGPGPCHTWKPRPELPDFRGDE
>NZ_CP011271.1|WP_082841082.1|5527786_5528137_+|hypothetical-protein
MGEPFSTYAKLLLAFDDANRDHHVALINGTASQRAEAELRRDKCQADIVSFQHHRANALLMDLRFAKMWSPAALELYLYPAFRDQLDSQELRIKELEDALLQLASHVGAITKTRSS
>NZ_CP011271.1|WP_082841081.1|5527237_5527660_+|hypothetical-protein
MSAKAELIVADMDGLKVDATTLHRQQLIKPLAELVEALTDEGLISMKDAAKLYGRKTNYATVRRHCLDGIVLPDGTRLHLEHIRLAGSIVTSKQAVIRFIAAQNETPPVSGQIRNRETPAQRTRAQAAASAEMGALLGAN
>NZ_CP011271.1|WP_082841080.1|5525687_5526881_+|tyrosine-type-recombinase/integrase
MARPKNPTPTYKHHKATGLARCWVNGRWVSLGKFNSPESRAEFARIIAELSHSPSVPVRGKSPRTPPTTIDQVMLAFFAHAAKHYVTRTGKPSEEYNEFRRAARPLHALYGHIPASDFGPRALATVRAEMVKTGLSRNVVNQRIGRIVRAFKWAVAEELVPVTVFEALRTLKGLQRGRTEARETDPITPVPAHHVTATLRFLNAHISAMIELQRLTGCRPGEICALRMADVDASDAVWLYRPVVHKTEHHGFDRVIPFGPRAQLVLRAFLDARPVEPAAPVFSPARAREERFALSRTRRKTKVPPSQVSRRNPTPLRVPAAQYSAHSFSQAVRKAALKALVPHWHPNQLRHAYATDVRRRFGLEAAQVLLGHASANVTQVYAERDLARALQVAREVG
>NZ_CP011271.1|WP_157469724.1|5522664_5525292_-|phenylalanine--tRNA-ligase-subunit-beta
MLVPLSWLKDYVPLPADPGALVERLTIAGLESSGVKVFGFPVQGTLRVKPEDAGLVWERDKLVVAQVLEITKHPNADSLKLVKLDLGTGAPKTVITGAENIAVGQSGMKIILGLCGSQYFFTGKDGKKTVMTLVPKRLREIDNDAMCMSDFELGIAEESEGIIILDDADAAPGTPAQDVLGEIVVELDILPNMARCLSMIGIAREVAALTGVSATIAEPKVETVAESIEGKVRVEIADPKLCPRYTATVIRNVTLGPAPRWMRSRLHYAGMRPISNAVDITNYVMLEHGQPLHAFDYDVLVTRAGGKAPTIIVRPAKPGEVLKTLDGQDRELSPENLVIADTAGPIALAGVMGGAETEVGAATKTILLESACFDFVSVRKTARQFNLFSEASTRFSRGVHPEQSLLAAVRAAQLFHDHAEGEVLTGVVDEYPAPLPPQVIDLDQNEIRRLLGFDIPSAEVVRVLTALQFQVEPDGDDAWTVTTPPTRLDIQAGAADLIEELARVYGYDNLKERLLPLELPEPKGNPDLEGEDRVRDLLADQGLQEAITYSLSSLEAEAKLGAGQNPSPTPPLNGEGLKTADDFSPPSFLGKGVGGLGSADFVALLNPLSPERGVLRRTLLPGLLAVAQKNLEAADSVAMYELGFAYLPVPGARLPREPRKLAIVLCGRRTGAAWDDPQGAVPARYDFYDLKGVVEALTSDLHLSSVTFAATGTVPWLHPMRAAELRVNGTAVGAFGELHPKVAAQFLLGDRAVQVAELDLEAVLAAVPARYGYKPFSTFPPAKRDVAVVVADATPAEAVLAEIRAAGGELLTDAALFDVYRGTGLPDGTKSLAFALTYQAPDRTLGEKEIVKAHEKVEGRLRHVLKAQIRGKDLA
>NZ_CP011271.1|WP_082841078.1|5521144_5522302_-|hypothetical-protein
MGMYPIDELAGSLVRRLSLRERALITRQQALDGLLAAVVWTVHDHPNQRPKIVAALSTLTPTVAAELIVWLAHKRAADGTWLWPPTGGHGDSGGSTKFTSAGPNQVAVYQTVIRLLRGRVADRPGTDFAPDQERTRTERRRELLDAVREHALPLGPFGDLDERNRLERGWQDTLTEEDCLELLRWLRGTDLTTRADVWDRGAVAEIPYHVGRVGRRCGGPRLLSFLLDLLGDALLYEPAFDVIFEIEESVEYENLLAGATVGSVPIHVELARMATPIQAERLRHVACSPGHSHNARTAIRDILRNIALIRGAPSRFVMFSPDWRTDTAVAIARRVSESRDFSALPVLADALQDAGCDNNDVLNHCREPGAHVCGCWVVDLVLDKG
>NZ_CP011271.1|WP_157470465.1|5520462_5520705_-|hypothetical-protein
MRDLFGNPFRPVSFSPAWRTSTVLALASQMYELRDFSALPILADALQDAGSDSTGVLDHCRGAGPHARGCRVVDLVLGKE
>NZ_CP011271.1|WP_052552385.1|5520238_5520466_-|hypothetical-protein
MRAPVTETEWLTGRYPWHALENLKNEPGKRKRRLFACACCYRLMDLYPTTEARAAVVAAGQFTNLDRVPSVSHPG
>NZ_CP011271.1|WP_082843376.1|5517558_5520186_-|magnesium-translocating-P-type-ATPase
MPTPVLPKRLPHGPHPAVAADHVSPLLVEASAADPDAALQQFGTSAAGLADEEAERRLRENGPNVVARDERHPRIRLLRKALVNPLVILLVVLSASSFLTGDPRAGCVILLMVLLGVVVRFVQEARADSAAAKLRAMISVHATVRRGGRAREVPVADLVQGDVVELAAGDMIPADVRLLACKDLFVTQGGLTGESFPVEKFAAREDAAGRSPLERTNVCYLGTSVESGAATAVVVATGLTTFLGGISTTLVEPQPPTSFDRGVTRFTWLMIYFIFVMVPTVFLINGLTKGDWAGAFFFALAVAVGMTPEMLPMIVAVCLSKGAIGMSRKRVIVKRLNAIQNLGAMDVLCTDKTGTLTQDRIVLEKHCDVTLKEDDEVLLLAYLNSHFQTGLKNLMDRAVLSHAEVHAHPSFADYAKVDEIPFDFSRRMMSVVVERPGAGHRLICKGAPEALYERCANFELDGEIQPVNPMFRADLKEEFDRLSADGFRVLAVAYRDFDARPAYSKDDERDLTLRGYVAFLDPPKDTARAAIAALRAGGVAVKVLTGDNELVSRKICRDVGIATDAVLVGNQVEGMSDAELAAAAGRATLFARLSPAHKQRVIRCLQGAGHAVGFLGDGINDAPALRGADVGISVDTATDIAKESADVILLEKDLLVLEEGVREGRKVFANILKYVRMGASSNFGNMFSVLGASAFLPFVPMLPIQVLANNLLYDFSQVAIPTDDADPEQVAKPRPWSIGQITRYILFIGPCSSAFDYVTFFIMLYGFGCWDPANASVFQTAWFVESLLTQTLIIHVIRTNRIPFLQSRASWPLIVSTIAVMLVGASLPFSPVGPLLGFAPLPLLYWPLLALILFGYVLLTQVVKTWLVRKSWVTG
>NZ_CP011271.1|WP_082843375.1|5516521_5516647_-|hypothetical-protein
MGALAGDRGARLEYPRTRAAELLGISRRQLFDKVRAYGLDG
>NZ_CP011271.1|WP_162271811.1|5530464_5530923_+|hypothetical-protein
MKQPPPNAGKGRPKGALNKSTKTVRDSVLAAFDKLGGVRWLVHLGRTNPVEFARLLGRLLPREVSVTSSSTTPPPPALSDPKVMAAALALDEACDAVSHALGSGAADAPALQVGEVPPRAPGEPPEAPGEATDPSERGTLSPFDDPTAPTAR
>NZ_CP011271.1|WP_162271812.1|5530894_5532199_+|hypothetical-protein
MIQLPPQHAKSLIASRLFPPIVFAQDPSAKLMLLSYGAELASGHGSIARDYVNEFREHLDPSGRLQVRRDSNAKNNWRTTSDGHMYSASIQGTVTGRAATGIIIDDAFKGSEDSGSIRIRDKVWDTYSAAAETRLTPDGFVILIGTPWHPDDLFGRLLANEADQWVRLRFPAIAEADDALGRAEGEGLFLSKYSQEWYEAKKRAFELRGQSHIWDALYNCSPTGDGSLRAFPDEYFGPWMWVEELPFNSRNREEFRVLSLDPSKSKTGKAGDYGAFCDLSLFSDRHIYATMHLAREPLPALYARAVAIVGAAKNEGRPYRRFIIESNQFQEAVGLAIQERLNAVGLDVPIDLHLTPSDQSKHARIQVDLGPLLAQKRLHFVGQTVSNKLTLQQMKEIPNGAHDDGPDAVSMATQALNLLLTGTKRPSDNKVLRT
>NZ_CP011271.1|WP_082841086.1|5532272_5533781_+|phage-portal-protein
MSFWAKLNPVNWFRGTLKEASQSDIYGTPVSDYELNTWNGRPLTPVWGPELFPDKLQTIRTLQELNRVRHVSRYLYERNPNASGGINGMGRYVVGCGSAQEVQSTDPDKEAPPALAKAVTALLDEFKKASRWKIIEREIYRRYLTDGECFIELTPMDDGITAVKFVEPDSIVPPEGQSFEGPWSWGILTRPDRPGVPVAYNVRDYSTNTERRVPAQFIFHLKRGTNLNQKRGLPALTACIDELQGGNKLRYASREGEKVRASIAYVRQFAQAPATAIQSLQSAQASGTFQRSTPNGTQDVTYQQIEPGTVQDIPEGLEYQPPPPSPNSEAAAMSVKLSLEATAAALEAPYWLISGDSTASSYASSLTAESPFIKLVEGEQSVLSEYVDDVLTAVIEIAAEQERDNIPMDVLDQIDLHVNYTVPVVRQKLDEAHRNEILRKAKIKSPQTISAEEGLDYEKEQANFVAAGPSPEEQAAQQEADLAAKQPQTAGGQMKRDQGSEA
>NZ_CP011271.1|WP_082841087.1|5533780_5534641_+|hypothetical-protein
MGQFIKTERLVETALWEDASAPANGVLPNVKILGQKSRNKRFYTEGAMKGAVSLYEGKAVYISHAREKIKHRDAPERFGRLKNVRFEPGKKELRGDLVYLESQAQMTAMLKEDLERGLNFFGLSHVADGQFHVKEGVKVVTKIDKVESVDLVSDPATATSLREQTDATAVADEFEQSVLAVLNDEALDAAGKKAKLQELSKPAAAAGAAVPTTPVKEQTETDPIKALTEQVTNLTKTVAALQQKPKKYVTSQQAQATTLTEQTDTTQTQLDAPPKDKAALKKWLRK
>NZ_CP011271.1|WP_082841088.1|5534712_5535219_+|hypothetical-protein
MADAKYSNAGRLISGMPQPKRVSGTVASAIYAGDFLILASNKASPASALADAGTKAQNQEAGHDVFLGVALDAKIAGDTRDVLIASRGEYKYPCAALGSASDPGAYVGIAGTGVGGADGLADQIVEIVATPNLAIGRLSRRAEIGATELFFELAGTLTTTHAGPQTMA
>NZ_CP011271.1|WP_082841089.1|5535294_5536557_+|hypothetical-protein
MAHLADKLKKILEQNMNEGRGLAGYRGQLREMFGITEDDNGSPFLNRAERLIDPLQLDAREIAMTFLGREVGGSDIRRAFALREQFGTFSEAEGAVVLPSHFARISAFTDTVAGLVDALTMEAYTAPEFIGDSLMEVKQERVNGGKMIGVMNDGGVSGDLLDGEPFPTVGLKETYVEIPDNQRYGNVIQINEKTFIYDRTDMLESSCKNAGTAVARNKEVRQADCVLGITNTYSRDGNAANTYLTTNGEIPNNYTNSSTNELTNYANIDTAFQILEGNTDPGTGFEITVAAPQLLVMPQRQMNLESVLYPEFVRRVTDTGNTLTQTQRSLIRPINPVVLSRIWYNRLIAAGVSTTNAPARWYMGDPKQAFRYRQIIPFQVNSAPLSSEDARREIVGIWVAREHGVPFTKEPRFMYRGTKE
>NZ_CP011271.1|WP_082841090.1|5536656_5536872_+|hypothetical-protein
MPTVADNLNATIAGYAAALAADSVNPQPSYELDGKRVDRNQWREGLQKLIDALQKTVNAQAPYIVSTKMVL
>NZ_CP011271.1|WP_157469726.1|5536868_5537231_+|hypothetical-protein
MMALDLSGDWALIDDPITISYESRLTENTYSAPAAVSYAQRNDVTKEDLDALSAFISKGLLQKDATVFHVWTAKLNGTVPAIKDRVTYAGEKWTVQIVGIRDRDANGPQRHRLVCSKFQG
>NZ_CP011271.1|WP_082841092.1|5537234_5537531_+|hypothetical-protein
MALNLNDRLAVMRSSAMQARCEAAVAKYALYLLGNGGSTVNQLAWAREAIRATAAVGSQVSYHVLDDTNFLAGGSDITDTQLQGAIETAVQTRFIASS
>NZ_CP011271.1|WP_082841093.1|5537530_5538211_+|hypothetical-protein
MSIANVQSANNATGSGASLNITVSALTAGNVIVVGARIANEALGVTPSATGVTFTTLLGPTNHSSAGVNVRAYLWLGVVNTGGATTVTLTLSSSSDTIHGWVSEFSGVATSSALDQTATAESVSAGTSGNISAPVTTTQADELLVANYALNGSATATPGSGYTNIVGGARAALGEYRIVSATGNYDCPFSWSSSFNWVVQFATLKGATTVSIVPLVVHHRKQQGMS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP011271_15

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_15

5649880-5649990

Orphan

Consensus_repeat	Method
GGAAGCCAACGAGACGCGCGCCGACGCCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_15

>merge|NZ_CP011271|15|5649880-5649990|CRISPRCasFinder
GGAAGCCAACGAGACGCGCGCCGACGCCGGTCCCCCCGCCTCATCGCGTGCGGAGGCGATGGGCCGCGCGGAACCCGCCACGGGAACCAACGAGACGCGCGCCGACGCCGG

>NZ_CP011271|15|15|5649880-5649990|CRISPRCasFinder
GGAAGCCAACGAGACGCGCGCCGACGCCGG	TCCCCCCGCCTCATCGCGTGCGGAGGCGATGGGCCGCGCGGAACCCGCCAC
GGGAACCAACGAGACGCGCGCCGACGCCGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_052552595.1\|5652497_5652800_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_157469746.1\|5642032_5642323_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082843388.1\|5644877_5645120_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052552589.1\|5647069_5648137_+\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
NZ_CP011271.1\|WP_052552593.1\|5651590_5652376_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052552598.1\|5653579_5654137_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_157469747.1\|5642749_5643559_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841165.1\|5639763_5640237_-\|GyrI-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|214874
NZ_CP011271.1\|WP_082843387.1\|5644184_5644418_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082843391.1\|5657750_5657984_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_157469749.1\|5655890_5656346_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052552578.1\|5640567_5640960_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_157469748.1\|5655271_5655532_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|132110
NZ_CP011271.1\|WP_082843389.1\|5645552_5645804_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082838323.1\|5656355_5657642_-\|IS701-family-transposase	unknown	unknown	gnl\|CDD\|379252
NZ_CP011271.1\|WP_157470469.1\|5654447_5654612_-\|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082843386.1\|5641672_5641882_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052552587.1\|5646261_5646825_-\|TIGR02996-domain-containing-protein	unknown	unknown	gnl\|CDD\|274381
NZ_CP011271.1\|WP_082841168.1\|5658023_5658674_-\|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082843390.1\|5653006_5653447_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275381

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_157469748.1\|5655271_5655532_-\|hypothetical-protein	gnl\|CDD\|132110	TIGR03066, Gem_osc_para_1, Gemmata obscuriglobus paralogous family TIGR03066. This model represents an uncharacterized paralogous family in Gemmata obscuriglobus UQM 2246, a member of the Planctomycetes. This family shows sequence similarity to TIGR03067, which is also found in Gemmata obscuriglobus as well as in a few other species. [Hypothetical proteins, Conserved].	0.00227161
NZ_CP011271.1\|WP_052552589.1\|5647069_5648137_+\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.66929e-25
NZ_CP011271.1\|WP_082843390.1\|5653006_5653447_-\|hypothetical-protein	gnl\|CDD\|275381	sd00034, LRR_AMN1, leucine-rich repeats, antagonist of mitotic exit network protein 1-like subfamily. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.	1.08055e-11
NZ_CP011271.1\|WP_082838323.1\|5656355_5657642_-\|IS701-family-transposase	gnl\|CDD\|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.63533e-46
NZ_CP011271.1\|WP_052552587.1\|5646261_5646825_-\|TIGR02996-domain-containing-protein	gnl\|CDD\|274381	TIGR02996, rpt_mate_G_obs, repeat-companion domain TIGR02996. This model describes an abundant paralogous domain of Gemmata obscuriglobus UQM 2246, a member of the Planctomycetes. The domain also occurs, although rarely, in Myxococcus xanthus DK 1622 and related species. Most member proteins have extensive repeats similar to the leucine-rich repeat, or another repeat class or region of low-complexity sequence. This domain is not repeated, and in Gemmata is usually found at the protein N-terminus.	1.70012e-07
NZ_CP011271.1\|WP_082841165.1\|5639763_5640237_-\|GyrI-like-domain-containing-protein	gnl\|CDD\|214874	smart00871, AraC_E_bind, Bacterial transcription activator, effector binding domain. This domain is found in the probable effector binding domain of a number of different bacterial transcription activators.and is also present in some DNA gyrase inhibitors. The absence of a HTH motif in the DNA gyrase inhibitors is thought to indicate the fact that these do not bind DNA.	6.70894e-09

>NZ_CP011271.1|WP_052552589.1|5647069_5648137_+|TlpA-family-protein-disulfide-reductase
MRVPFSPIVALACALLPPNAARGEPPEKPAEKAPTLKVGDAAPPLRVTKWLNGTEVKRFEPGKVFVVEFWATWCGPCMGVMPQLAALQTEYKDKGLTVIGVTAKDENNSAAAVEAFVDKKGKRYGYTFAFCADRTTYDAYMTAAGLQGIPSAFVVGPTGKIEFIGHSMELDLVLPKVLAGTWRGQADIDQIRKDFGRFAGIMKKAQTDPAAALKEFDAFASEFPKLTAGYYYRLKKLQLLLMGKEFDAARELSEALIRSAAEPPNTVLLNGVQLMWSTSFVNPDKKHADLALKAAEAELKIEGARSPAALFHVAEAHAFAGDTAKATEYGQKAIAAAGDAERKGYEDALKKLLGK
>NZ_CP011271.1|WP_052552587.1|5646261_5646825_-|TIGR02996-domain-containing-protein
MTDDNRAFIASIAAAPDDPLPPLVYADWMDDRGDPRGPLLRVWADLAWRASHAGSGFRALLAEYRRLWHAADPDWRSAFGAARPWVSAQLAEELCRGYFRYVKQPFIRGEVIPGQANWFTEPGEPDSRGWLVRYWADYRSFGDRRPQRLRWMLFVQADLGWVYTIAARGPRFELQQFDVIAGEGRAF
>NZ_CP011271.1|WP_082843389.1|5645552_5645804_+|hypothetical-protein
MHFLRDIFGNPFRPVTFSPEWRTSAVVALAAQMYESRDFSAMPILGDALQDAGCDRADVLSHCRGPGPHVRGCWVVDLVLGKE
>NZ_CP011271.1|WP_082843388.1|5644877_5645120_+|hypothetical-protein
MRDIFGNSFEPIIFSPSWRTSTAVALASQMYKARDFSAMPILADALQDAGCDRADMLDHCRGPGPHVRGCWVADLVLRKK
>NZ_CP011271.1|WP_082843387.1|5644184_5644418_+|hypothetical-protein
MVGNPFRPVTFFPSWRTSTAVTLASQMYESREFGAMPILADALQDAGCDNADALDHCRGPGPHVRGCWVVDMVLGKE
>NZ_CP011271.1|WP_157469747.1|5642749_5643559_-|hypothetical-protein
MRRLRLDALQLHSDRLHLCGQLFDGIAYEVRADRVVANFRVTGGVRKGPAEAWAARRPRVLFQSLAFPSGEEAPEPTEHATLNGTPFHGVSYSFDPATGSLLQELDLHPTRPGPSREWFPSGRPKAEIDRARPDGTTESEAWYENGQRETYESLDLDAGYTPDGRLRTLRVECDCADGDLDRLSFSADSVLDLAGPGVTDAVVERLAGLSHVEDLELRRTNVSATGLMRFSACLGLTRFRVRRNAQFGEVDVRNVLARLPNCQWDGRLN
>NZ_CP011271.1|WP_157469746.1|5642032_5642323_+|hypothetical-protein
MVAVLLSFAIASAVPTDVALPRFTVPKLIPFEPGNPRPSDAQRELLEITEYLIKDAEETIEYLEKSGLDSTLLGEYRVELKKLIQLRSKLQKGIKK
>NZ_CP011271.1|WP_082843386.1|5641672_5641882_+|hypothetical-protein
MAIDPSWRTSTAVALASQMYESRDFGAMPILGDALQDAGCDSADVLGHCRGPGPHVRGCWVVDLVLGKE
>NZ_CP011271.1|WP_052552578.1|5640567_5640960_-|hypothetical-protein
MKAILSVAMVLGLCGAAGARDEKANPVGTWQCEYEIGGMKRTSTLTIKKDGDKLTGTMDWADQKGEKLKDVKLKDGVLTFSAVRKFMDNEIALDYKLTIEKEKFKGKAAAEIGGEKQEFDIEGKREKKDK
>NZ_CP011271.1|WP_082841165.1|5639763_5640237_-|GyrI-like-domain-containing-protein
MEHVVRLEQVSSKSLAVVRRRAAAWELSKIVPDACGIVWNVGRSQRVAGAGRHVAVYLDDQINLEVGVEVSAPFAGHGEVIGSATPPGLTATTTHYGPYHRLHEAHGAIRQWCGSNGYRPAGPSWEIYGHWKDEWNNDPAQIVTNVFYLLVADGSSS
>NZ_CP011271.1|WP_052552593.1|5651590_5652376_-|hypothetical-protein
MRAFIGPRHGPLILVALLAPVPGARGDDLPAPKKPAEECVVGALQFKSRAGAFTGTDVGQPGLARKYISGNPNSTERAVWGFDALPQSVTAPAGDTVPAKLTCSIFYMKKSPPGARVTVRVVSHTCPQVPDQLRAEWQWAGDKADAQKEQYDKAVAAYKDKKLDPGAEKPDAASWKAANELAEKYGYYEVTVPKVFDDAEATVDLPAGLFRNALKHKPEAHADGTPKRPLVSVYVKCETPGVLIGMTDADLYLHLPKPVPK
>NZ_CP011271.1|WP_052552595.1|5652497_5652800_-|hypothetical-protein
MIELLVAVAIAVGGPAVTDVEPPTDAQVLAALPFAVRNDIAMAKELLSTRITTATVDGQTTVRFVRRWECAVSYTAGPGENGAPPARFRHVTTVETVTRK
>NZ_CP011271.1|WP_082843390.1|5653006_5653447_-|hypothetical-protein
MFYGVLHREAPRDEPPPDKPVTTLDLSRIQVTDANLRELVVLKDLTVLKLSSTAVTDAGLKNLAALKGLTSLDLSDTVVTGTGLKDLAALKSLTTLTLGGEKITDTGIKHLTALKNLKELSLAGTKVTAAGLKELQAALPKCKIVQ
>NZ_CP011271.1|WP_052552598.1|5653579_5654137_-|hypothetical-protein
MARVMLSSEEVGPGVLPPCCLVCGAKAEGAARASMRSVPVWCYFLLFLGFLPFAIAYVLSRQEITVSAPVCSRHRSHFLWRQWLLPAGILAALLTLVSPVVIQPDARPFPPTWALIGTVALLAGTVTAVIWLRQTGVRVASMSRDAVELDGVSPDFVSALELGRADYKRRMQEWLERHDRAPSSR
>NZ_CP011271.1|WP_157470469.1|5654447_5654612_-|PEP-CTERM-sorting-domain-containing-protein
MGTTPNGALVVSASPSATPEPTTLALAGIGLTALGVARRVRGRNTAARVGTATA
>NZ_CP011271.1|WP_157469748.1|5655271_5655532_-|hypothetical-protein
MRLFIQLSLPDAEPLPHRLPKHLMKEEKVAPVKVVGTWTPKERPELGTVEYTKGARGCALLHPGLHAAAPFGAPLVVLSPGRGAGP
>NZ_CP011271.1|WP_157469749.1|5655890_5656346_+|hypothetical-protein
MTEVEWLQTRRFRAALQVFVAPPAASGVLGRVRGWLKAPRPAPRSTSKRQMLLALAGIGRRLWAASGHGNEAGHREWIERCERFADGCPTPEDQTILGPPYGPGAAIHAEYLFYPAALRAPSPLAAVQRIVAELAPTLPALTRLINTTARV
>NZ_CP011271.1|WP_082838323.1|5656355_5657642_-|IS701-family-transposase
MTDQEIARLGPAFAHYLGRYRGCFLQKRTADHFDNYGRGLLSELPRKSVEPIALACGTAVRTLQEFLTTADWQHESAREQLQRRCAEVLDGLPGDDLGTVGVIDETSAVKKGDRTPGVQRQYLGCVGKIDNGIVTVHVGVAKGTFQALLDADLYLPESWNADRPRCQAAGIPDEVRYRPKWRIAYEQLVRLDAHGVRFDWLVFDEGYGSKVPFLRALDAVGQPFVGEVPVSFSVTTAARDEPRRADSVLRADDARRGRRFRVSRKTVGDTRWRATSRLIEVRGCRWMLVVAQNESTAEVKYFVTNATDEPLARVLRVAFRRATIEHQFRVAKSEAGMTHYEGRQYVGLVRHLILGLVVLGFVSIHTDRLRGEKTAGDDGAGVPGAERPMCGDVPSEARDAGTTARRRGHPLPPTAERAGHESAQKMAT
>NZ_CP011271.1|WP_082843391.1|5657750_5657984_+|hypothetical-protein
MFGNPFRPVTLSPSWRTDTVLTLATQMYESRDFGAMPILGDALQDAGCDSADVLDHCRGDGPHVRGCWVVDQVLGKE
>NZ_CP011271.1|WP_082841168.1|5658023_5658674_-|PEP-CTERM-sorting-domain-containing-protein
MHQLLRPVFVATALVLSPLIASAGPISWNYTGTVTGNKSGTYDYGPTARPDSTSPTGLRYGEVVGQVGTVNGSGAHIDAARLELGGLLDGTVWTQWHDTGRRMASDALSDQVLADLTITDAASGAQGHFWVTGTGDLTGDPMLSAYQLSLLIDGNANQERTIGGNRYRVHFDTEVTASGAMVVADVSVASATPEPGTLALAALGFSALGIIRLRRR

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Crispr_ID: NZ_CP011271_16

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_16

5693618-5693734

Orphan

Consensus_repeat	Method
CCCCGGGCTATTCCCGGTGACCCCTTCGGGGTCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_16

>merge|NZ_CP011271|16|5693618-5693734|CRISPRCasFinder
CCCCGGGCTATTCCCGGTGACCCCTTCGGGGTCCAAAGACCGTGAAGGGGTTGCGTCCCCAACGAGAAATCCCGGGGTTGAAACCCCGGGCTATTCCCGGTGCCCCCTTCGGGGTCC

>NZ_CP011271|16|16|5693618-5693734|CRISPRCasFinder
CCCCGGGCTATTCCCGGTGACCCCTTCGGGGTCC	AAAGACCGTGAAGGGGTTGCGTCCCCAACGAGAAATCCCGGGGTTGAAA
CCCCGGGCTATTCCCGGTGCCCCCTTCGGGGTCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_082841184.1\|5685476_5686028_-\|SMI1/KNR4-family-protein	unknown	unknown	gnl\|CDD\|378155
NZ_CP011271.1\|WP_082843393.1\|5683400_5683691_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841194.1\|5703396_5706177_-\|peptidase	unknown	unknown	gnl\|CDD\|225913
NZ_CP011271.1\|WP_082841191.1\|5696133_5697090_+\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NZ_CP011271.1\|WP_082841190.1\|5695018_5696137_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841188.1\|5691012_5692389_-\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_CP011271.1\|WP_052552667.1\|5701692_5702463_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841195.1\|5706610_5706847_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082843394.1\|5686096_5686366_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052552663.1\|5698812_5699148_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|184358
NZ_CP011271.1\|WP_082841193.1\|5698297_5698633_+\|ribosomal-subunit-interface-protein	unknown	unknown	gnl\|CDD\|238308
NZ_CP011271.1\|WP_082841185.1\|5687396_5688068_-\|carbonic-anhydrase	unknown	unknown	gnl\|CDD\|238449
NZ_CP011271.1\|WP_082841186.1\|5688266_5688815_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379049
NZ_CP011271.1\|WP_157469753.1\|5692437_5693580_-\|TIGR02996-domain-containing-protein	unknown	unknown	gnl\|CDD\|274381
NZ_CP011271.1\|WP_082841192.1\|5697283_5697895_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_157469754.1\|5693917_5694589_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|340878
NZ_CP011271.1\|WP_157469752.1\|5684252_5685062_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841187.1\|5689485_5690037_-\|SMI1/KNR4-family-protein	unknown	unknown	gnl\|CDD\|378155
NZ_CP011271.1\|WP_157470471.1\|5690105_5690366_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052552665.1\|5699916_5701491_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_157469754.1\|5693917_5694589_+\|hypothetical-protein	gnl\|CDD\|340878	cd17320, MFS_MdfA_MDR_like, Multidrug transporter MdfA and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as MdfA (also called chloramphenicol resistance pump Cmr), EmrD, MdtM, MdtL, bicyclomycin resistance protein (also called sulfonamide resistance protein), and the uncharacterized inner membrane transport protein YdhC. EmrD is a proton-dependent secondary transporter, first identified as an efflux pump for uncouplers of oxidative phosphorylation. It expels a range of drug molecules and amphipathic compounds across the inner membrane of E. coli. Similarly, MdfA is a secondary multidrug transporter that exports a broad spectrum of structurally and electrically dissimilar toxic compounds. These MDR transporters are drug/H+ antiporters (DHA) belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	0.00492103
NZ_CP011271.1\|WP_082841184.1\|5685476_5686028_-\|SMI1/KNR4-family-protein	gnl\|CDD\|378155	pfam09346, SMI1_KNR4, SMI1 / KNR4 family (SUKH-1). Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Genome contextual information showed that SMI1 are primary immunity proteins in bacterial toxin systems.	8.02383e-22
NZ_CP011271.1\|WP_082841185.1\|5687396_5688068_-\|carbonic-anhydrase	gnl\|CDD\|238449	cd00884, beta_CA_cladeB, Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.	7.70782e-95
NZ_CP011271.1\|WP_082841186.1\|5688266_5688815_-\|hypothetical-protein	gnl\|CDD\|379049	pfam13173, AAA_14, AAA domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	0.00133151
NZ_CP011271.1\|WP_157469753.1\|5692437_5693580_-\|TIGR02996-domain-containing-protein	gnl\|CDD\|274381	TIGR02996, rpt_mate_G_obs, repeat-companion domain TIGR02996. This model describes an abundant paralogous domain of Gemmata obscuriglobus UQM 2246, a member of the Planctomycetes. The domain also occurs, although rarely, in Myxococcus xanthus DK 1622 and related species. Most member proteins have extensive repeats similar to the leucine-rich repeat, or another repeat class or region of low-complexity sequence. This domain is not repeated, and in Gemmata is usually found at the protein N-terminus.	1.65559e-11
NZ_CP011271.1\|WP_082841193.1\|5698297_5698633_+\|ribosomal-subunit-interface-protein	gnl\|CDD\|238308	cd00552, RaiA, RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY, is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal A site. RaiA is also thought to counteract miscoding at the A site thus reducing translation errors. The RaiA fold structurally resembles the double-stranded RNA-binding domain (dsRBD).	0.00631516
NZ_CP011271.1\|WP_082841188.1\|5691012_5692389_-\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	3.14643e-44
NZ_CP011271.1\|WP_082841194.1\|5703396_5706177_-\|peptidase	gnl\|CDD\|225913	COG3378, COG3378, Phage associated DNA primase [General function prediction only].	1.59231e-61
NZ_CP011271.1\|WP_052552663.1\|5698812_5699148_-\|hypothetical-protein	gnl\|CDD\|184358	PRK13874, PRK13874, conjugal transfer protein TrbJ; Provisional.	0.00340741
NZ_CP011271.1\|WP_082841187.1\|5689485_5690037_-\|SMI1/KNR4-family-protein	gnl\|CDD\|378155	pfam09346, SMI1_KNR4, SMI1 / KNR4 family (SUKH-1). Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Genome contextual information showed that SMI1 are primary immunity proteins in bacterial toxin systems.	3.29445e-21
NZ_CP011271.1\|WP_082841191.1\|5696133_5697090_+\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	1.79417e-37

>NZ_CP011271.1|WP_157469753.1|5692437_5693580_-|TIGR02996-domain-containing-protein
MSTPDRHPDETAFLAAIAAAPDDATARLVFADWLEERSDPRAAWVRDADIWEWMKPDARDPVPGILKTLTVLRPGVRSSIEREKINWKRRGSAEAALFEMGTSAVDAVRTWIREHPDQVPGEAVQIFMRCSKPDKLQSVLTLQTKLDAQSWVDVWLAVVDLGFHKAAAAPSVTALTEIEGWKRWPEFNDSMDSVERPVENAICYTLGQIGPAALEAVRWLASNMWLYPESAAEALIQLRADPDLIVEHINTDEDHEVQSGIRSILELASDPVAFLVRNAQQRTGRVAYTSLRLLAEMGQKLLLPCPHSGISSTTEPNGIRTTSATRRTWRFRRSTQRTDPRHRHLVPTSPAGSHRPFARHLRRPRAENERRVAFRLLVRA
>NZ_CP011271.1|WP_082841188.1|5691012_5692389_-|Gfo/Idh/MocA-family-oxidoreductase
MDRRHFLRTSSAAALAVPAGGYFVVGAEPKPLRVGLVGTGWYGKCSLFRLLQVAPVEVVALCDVDKKMLAEAADLITARAKAPKKPRLHADYRELLKEKDCDVVMVETPDHWHALPAIAAMEAGADVWVQKPVSVDVLEGKAMLDAARKHKKVVQVVTQRRSTPHLVDAKEKVIKEGKLGTVGHVEICCYYHMRSGDKPPVTKVPEFFDYEMWTGPAPLREYDAPFYKDLDANLPHRRWWRAFTEYGNGIVGDMCIHMLDMVRWMLDLGWPTRVSSTGGILVQKNAKSNISDTQSATFEFPSLTVTWQHRTWGSTPDPEYPWAAFIYGDRGTLKASVNKYEFFPQGSNRPTVTGTALFEEDKFPEDKTEKDLERHVASALRRHWQDFLKARESRGKPVADIEQGHISSASCILANLSQQLGRSITWNPEKHICVGDDEATKLLKRPYRAPWKHPADAV
>NZ_CP011271.1|WP_157470471.1|5690105_5690366_-|hypothetical-protein
MDQCRRLRDIFGNPFRPVPFSPSWRTSTAVALAAQMYESREFGAMPILGDALQDAGCDSADVLDHCRGEGPHVRGCWVVDLVLGKE
>NZ_CP011271.1|WP_082841187.1|5689485_5690037_-|SMI1/KNR4-family-protein
MTIDDLIAALEATADRARSPLALRVFGPDRTPPPSPAQVEAFEAEIGAPLPDEYRAFLLRCNGGNLDGYQFDGPTPEGEWTAVVSRVGGLRDEPHLSLRSARASYQGYEVQIPRALVWIMGDPGGNAICLGLTGEHRGRVYFWVHDEGPDPDSWDGAVETAGNVVLLANSFTDFVAGLRAREE
>NZ_CP011271.1|WP_082841186.1|5688266_5688815_-|hypothetical-protein
MSTGPVHKAIVLRGPPGVGKSAVRDLLRAHLGKSVRYINLDAHWGKGEWRCAYPEFRYADLQLATEPVLVIELAWGEPDGLAFPGATRGANEWMGILKAAKREIFPFFLTAQWSDILKRLTDRHGHDGNHNVLAELGRASFYEHNHALFCYPDIPGITERTVDTTGKTAEAVAEAIKKIAGV
>NZ_CP011271.1|WP_082841185.1|5687396_5688068_-|carbonic-anhydrase
MQKLIQGIHRFRTEDFRPLQGLFEQLAKGQNPETLFITCSDSRIDPNLLTRSQPGDLFILRNAGNIVPSHGAASGGEAATIEFAVAGLGVRDIIICGHSHCGAMKGLLQPETVAALPAVTSWLSHAETTRRIVRDNYGHLEGERLVTATVEENVLVQLENLRTLPAVASRLVRGDLHLHGWVYKIETGEVFAYDTSSGQFVPLAQYQYQPSEAAARRRTSGAI
>NZ_CP011271.1|WP_082843394.1|5686096_5686366_-|hypothetical-protein
MEYRWQAAVLRDLFGNPSRPVTFSPSWRTSTAVALAAQMYEAREFGAMPILGDALQDAGCDSADVLDHCRGEGPHVRGCWVVDLVLGKE
>NZ_CP011271.1|WP_082841184.1|5685476_5686028_-|SMI1/KNR4-family-protein
MTIDDLIAALHATADRALSPLALRVFGPDRTPPPSPAQVEAFEAEIGAPLPDEYREFLLRCNGGNLDGYQFDGPTPEGEWTAVVSRVGGLRDERHLSLRSARASYQGYEVQIPRALVWIMGDPGGNAICLGLTGAHRGRVYFWVHDEGPDPDSWDGAVETAGNVVLLANSFADFIAGLRARDE
>NZ_CP011271.1|WP_157469752.1|5684252_5685062_+|hypothetical-protein
MRRLRLDALQLHSDRLHLCGQLFDGIAYEVRADRVVANFRVTGGVRKGPAEAWAARRPRVLFQSLAFPSGEEAPEPTEHATLNGTPFHGVSYSFDPATGSLLQELDLHPTRPGPSREWFPSGRPKAEIDRARPDGTTESEAWYENGQRETYESLDLDAGYTPDGRLRTLRVECDCADGDLDRLSFSADLVLDLAGPGVTDAVVERLADLSHVEDLELRRTNVTATGLMRFSACLGLTRFRVRRNAQFGEIDVRNVLARLPNCQWDGRLN
>NZ_CP011271.1|WP_082843393.1|5683400_5683691_-|hypothetical-protein
MLLDVDAEPYLLFCDLLRDIVGNPFRPVTFSPAWRTSTAVTLAAQMYESREFSVMPILADALQDAGCDSADVLNHCRVPGVHVRGCWVVDLVLGKA
>NZ_CP011271.1|WP_157469754.1|5693917_5694589_+|hypothetical-protein
MNELPEELPEELPEELPEDLPPPPPARPGLILAAGGLWVLVGAFFLLMTCLGTVLDILLEAGRQGPVRNSTAGCAMQVNMLIWGGFLTAGIRTLQGKAKDTIITSVMSILVGLLYFVIGAVSLWLAGGPGRAPGPFVTAMLVTGALSVLLGGALFLPAVLALAARSQYLEWREALEPPRRRRTRRRREEQDEERDWERPKYPRDPKRPWNRARRDSDDDDSWG
>NZ_CP011271.1|WP_082841190.1|5695018_5696137_+|hypothetical-protein
MEFASLIFLVLSPGAPTDKAEAVVAQKSRMPNRYQLKLRVESRTPNAPPPLESSWDSTLHIWRDGNKLRVDHLDAHYTPPRPNHDSHDRRITCENCEREGYGIVTTVVRGAPPTLHAVEFVRLGTRNLDGYCTFFDWRYFGLSNDRMCGYSRLHIGTDFPGFFGRPEVQTRNENRDGVPCLVATMSRKTANLQQSVWLSERDGFHPIFFEDKFEVEGKPESRTAEVSWQLTPGGHRYPKTMKHDTTISFNGAKYRSEEVVTVTHADFDSAIDPAVFTLAGFGLNENQAIRLPDLEPSKLPLWRNGKVDESYTLGQYTADMLGPPTAVADGPKTVASYPTEGNTTLIVSFVAALLATVAAVLAVVIRRRRAAG
>NZ_CP011271.1|WP_082841191.1|5696133_5697090_+|DUF1559-domain-containing-protein
MTEPNRSLRRRGVSLVEVLVVLSLLSFLFALLIPAVQSARAAAARISCRSNLRQIALATHSYESAHGQLPPAFRHRRTDAETPNLQWPLLIAPYLELGANWQTAVDDFRRDRDAIFPTPHRGLSVPLKPFSCPSDPRTAVSWEVKFVYTLARPRPTLVTRSFALNSYLGNGGEFSARRDGVIVADGTVTLLHVTDGTSNTLAFGERPPPRNLMLGWLYYGWGAHANGVGELSSVMGVNDPNPFARRVPDTSCGPGPFPYQQPDLNSEADCAQFQYWSLHSGGANFAFCDGSVRFLTYRANSVLAALATSAGGEVVAPD
>NZ_CP011271.1|WP_082841192.1|5697283_5697895_+|hypothetical-protein
MMRLIVALFASGALIGLAPAAPVPKHLMPKEPLYYSVQKGTRWVYTDNGMDCEFEATDVKPLARDGWTVTVECVRDGAKSPYQKIEVSPRGLVVIEARGISAENPLCLLQRPAEPNAEWSYRRDNPGATYSRGAMMVTGTEDVKVPAGVFRAVRVVHEVTVVWNDKPIQQLRVTTWYAPDVGLVKATGEGYKSELKSFTPGKG
>NZ_CP011271.1|WP_082841193.1|5698297_5698633_+|ribosomal-subunit-interface-protein
MHVEVNTDTRTSVDATAATTRIENGLARYRERLTRVEAHLSDVNGPKGGHDIRCALEARPAGHQPLAVTNEAHTPEDSVKGAVEKMGRLLEHTFGRIDDAKGHTSASGLPT
>NZ_CP011271.1|WP_052552663.1|5698812_5699148_-|hypothetical-protein
MRASLLTAAAAAALTFTLGTANDAKAQIIVYPSVNSSPYVTPVGYTYPSYSYNYAYNYPGLRTYSYGWTNPYSTWQWAGYRTYPTYPAYYGGYTGYYGGPRYYGGWRGRRW
>NZ_CP011271.1|WP_052552665.1|5699916_5701491_+|hypothetical-protein
MDSPFGLRSRISRLLTAPVREPRRAPRARLMAEALEAREVPARVNFTFALDESAGSFGLTTTQRNLFLTDLQAAGQLWSDQIAGAAANPVTLEVRVVPAALGSSTYANCGPTAQVVSGGVSEAGTLYESRTGVDPNGAVSDITMTFNTAYLQSSASFPVGAFFDPSGAARTGTVPAGQADVISVALHEMGHGLGIVSARNSSGVVPPGVAPTTFDTKISGTAFVGAQAQVVNGGAVPLSADYSHLNVSGDLMFPSIGGGVRRSIGGLDTAVLRDLGWAPVITATAATASATFSLDSAGNLFRQAGGTTTLVALAITDMEVVQGQLFVRNGGNNVFRYNAAGGFDFIAASVLQIGQGLNQFFVLNGGNNVYRYNWSTGGFDLLASAVLEIGQGQGQFFVRNGGNNVFRYNAAGGFDLLASAVVKIGSSQGDFLVLNGGNNVYRYNGSTGGFDLIATSVLEMESSQGQVFVRNSGNAVYRYSGGGFALSTVNIIDIWSSGGLFYVKRSDGAIFRYSPGLGDYILSA
>NZ_CP011271.1|WP_052552667.1|5701692_5702463_-|hypothetical-protein
MPDASVPTVRLGNLTFHLPFAGLLRPLSPLELTELRTSISRHNKVLNRAVTYDSATWGTRCVIDGANRLQIAAELDLDVPVQHRGAMPDEDARAECLDLNLARRHLTVEELEAARTGRILRVMAAKEEGQSTRAIARAEGVSQTQILRDLAVAAAPAPTFAPVPETDVSHDDQSVPEPDPARPLAVMQRSFRQIMYLSKSAKSGALPELLAGPLGGHLSRIAARHGVPLAGDRWPALEVLVAVVSDLAAEAAQGWE
>NZ_CP011271.1|WP_082841194.1|5703396_5706177_-|peptidase
MRPQGRRVAPLQYAPWEPTRPGNLWRTGVLTPVTTIAWHARADDLARWAALRIVNRTDRCGGCWVDTGGVHRTTRPVKGPSPGFVNHELLARHFRARGTADVIGLHALGTDGAGKWVGVDIDAHPGTPTDPAVNERFARTLYDDLRALGFAPLLSESNGTGGYHLRALFADPVEGPVLFAFGRWLVRRAGEFGFPRPPEVFPKQATLDGSTKFGNWLRLIGRHHARDFWPRVWSGAGWLEGASAVEHVLGLTGEPASLIPDAALTYNPNPPAPRAPVPTQAPAEDVFASFNRSQTMETMAALLQAHRWEPAGRRGPRWDFRRPGKNGDKSGNLMLVSGVPIFYGFTDAAGIPDHRGLNPSQLRAALEHGNNFAALAERLRTEGYGPPRRAPIPRPTEARSTRTSPATKAPDAPEAPPPQDPVHEDFLDPHRLGRLLVPRIGDLPTLIYHRAEWWEWKRGRYVTVTDDDFSKRAWTILREECEADHRVAVANWEADGRRNARPKVVKLDGRKVGNAIHAAASMCHLDGDTTWPLMLTADAPQPGRIPRLRPVAPQREYIACANGLIDVAELLASGTATVLPATPLFFTPAALPVKFEPGTRCPKFEAFLGRITDGDTERVAVLQEMAGYLLRYDSHFQTFFVLSGDGSNGKSTFLAALRALVGDWNYSSVPLEEFGERFALAGTLGKLVNAVAEVGEMDRVAEAKLKSFVSGDLMSFDRKNKTPLHTRPTARLLLLTNTLPRFADRTEGVWRRYQLVPFTAVISDSERVRGMSEPEWWAASGELPGILNWALDGLCRLYRQGHFTASQTCEAAKAEHRELCNPHRQFLDEHLKPAPTAQLRTTELFAAYVEWCRQRRYLPLSDGNFGGELRKVFREVKRARPREGRERQNMYVGVTWTEGRPDALLVDYDRRRRDAPGWSPGGDDED
>NZ_CP011271.1|WP_082841195.1|5706610_5706847_-|hypothetical-protein
MSQRATSNRCNHPRVLVCVDPNGTEIWRCPVCVTDRVVHWAPPRFDPPATFRERPCHDDEDDPAFENAVRALEDALRD

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Crispr_ID: NZ_CP011271_17

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_17

5706172-5706256

Orphan

Consensus_repeat	Method
GCGCATCGATGCCCGAGGTGGAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_17

>merge|NZ_CP011271|17|5706172-5706256|CRISPRCasFinder
GCGCATCGATGCCCGAGGTGGAGGCGCGCCAGGGAGTGCGTGGGGGTCCACCAGGGGTTGTGCGCATCGATGCCCGAGGTGGGGT

>NZ_CP011271|17|17|5706172-5706256|CRISPRCasFinder
GCGCATCGATGCCCGAGGTGGAGG	CGCGCCAGGGAGTGCGTGGGGGTCCACCAGGGGTTGT
GCGCATCGATGCCCGAGGTGGGGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_082841198.1\|5708963_5709677_+\|MOSC-domain-containing-protein	unknown	unknown	gnl\|CDD\|225167
NZ_CP011271.1\|WP_082841188.1\|5691012_5692389_-\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_CP011271.1\|WP_052552665.1\|5699916_5701491_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841190.1\|5695018_5696137_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052552663.1\|5698812_5699148_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|184358
NZ_CP011271.1\|WP_157469755.1\|5707027_5707186_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_162271822.1\|5708479_5708902_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227116
NZ_CP011271.1\|WP_082843396.1\|5714143_5715658_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052552667.1\|5701692_5702463_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841193.1\|5698297_5698633_+\|ribosomal-subunit-interface-protein	unknown	unknown	gnl\|CDD\|238308
NZ_CP011271.1\|WP_082841201.1\|5713728_5714160_+\|terminase-small-subunit	unknown	unknown	gnl\|CDD\|377071
NZ_CP011271.1\|WP_157469753.1\|5692437_5693580_-\|TIGR02996-domain-containing-protein	unknown	unknown	gnl\|CDD\|274381
NZ_CP011271.1\|WP_082841192.1\|5697283_5697895_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841200.1\|5712140_5712587_-\|TIGR03067-domain-containing-protein	unknown	unknown	gnl\|CDD\|274415
NZ_CP011271.1\|WP_157469754.1\|5693917_5694589_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|340878
NZ_CP011271.1\|WP_162271821.1\|5707688_5708300_+\|repressor-LexA	unknown	unknown	gnl\|CDD\|234688
NZ_CP011271.1\|WP_052552672.1\|5707248_5707497_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841199.1\|5710108_5712052_+\|PAS-domain-containing-hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl\|CDD\|237425
NZ_CP011271.1\|WP_082841195.1\|5706610_5706847_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841191.1\|5696133_5697090_+\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_082841198.1\|5708963_5709677_+\|MOSC-domain-containing-protein	gnl\|CDD\|225167	COG2258, COG2258, Uncharacterized protein conserved in bacteria [Function unknown].	7.23728e-75
NZ_CP011271.1\|WP_082841191.1\|5696133_5697090_+\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	1.79417e-37
NZ_CP011271.1\|WP_052552663.1\|5698812_5699148_-\|hypothetical-protein	gnl\|CDD\|184358	PRK13874, PRK13874, conjugal transfer protein TrbJ; Provisional.	0.00340741
NZ_CP011271.1\|WP_162271822.1\|5708479_5708902_+\|hypothetical-protein	gnl\|CDD\|227116	COG4775, COG4775, Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane].	5.56399e-09
NZ_CP011271.1\|WP_082841188.1\|5691012_5692389_-\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	3.14643e-44
NZ_CP011271.1\|WP_082841193.1\|5698297_5698633_+\|ribosomal-subunit-interface-protein	gnl\|CDD\|238308	cd00552, RaiA, RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY, is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal A site. RaiA is also thought to counteract miscoding at the A site thus reducing translation errors. The RaiA fold structurally resembles the double-stranded RNA-binding domain (dsRBD).	0.00631516
NZ_CP011271.1\|WP_082841201.1\|5713728_5714160_+\|terminase-small-subunit	gnl\|CDD\|377071	pfam03592, Terminase_2, Terminase small subunit. Packaging of double-stranded viral DNA concatemers requires interaction of the prohead with virus DNA. This process is mediated by a phage-encoded DNA recognition and terminase protein. The terminase enzymes described so far, which are hetero-oligomers composed of a small and a large subunit, do not have a significant level of sequence homology. The small terminase subunit is thought to form a nucleoprotein structure that helps to position the terminase large subunit at the packaging initiation site.	1.47815e-16
NZ_CP011271.1\|WP_157469753.1\|5692437_5693580_-\|TIGR02996-domain-containing-protein	gnl\|CDD\|274381	TIGR02996, rpt_mate_G_obs, repeat-companion domain TIGR02996. This model describes an abundant paralogous domain of Gemmata obscuriglobus UQM 2246, a member of the Planctomycetes. The domain also occurs, although rarely, in Myxococcus xanthus DK 1622 and related species. Most member proteins have extensive repeats similar to the leucine-rich repeat, or another repeat class or region of low-complexity sequence. This domain is not repeated, and in Gemmata is usually found at the protein N-terminus.	1.65559e-11
NZ_CP011271.1\|WP_082841200.1\|5712140_5712587_-\|TIGR03067-domain-containing-protein	gnl\|CDD\|274415	TIGR03067, Planc_TIGR03067, Planctomycetes uncharacterized domain TIGR03067. This domain occurs in several species, mostly from the Planctomycetes division of the bacteria. It is expanded into a paralogous family of at least twenty-five members in Gemmata obscuriglobus UQM 2246. This family appears related to TIGR03066, which also is expanded into a large paralogous family in Gemmata obscuriglobus. [Unknown function, General].	2.73998e-20
NZ_CP011271.1\|WP_157469754.1\|5693917_5694589_+\|hypothetical-protein	gnl\|CDD\|340878	cd17320, MFS_MdfA_MDR_like, Multidrug transporter MdfA and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as MdfA (also called chloramphenicol resistance pump Cmr), EmrD, MdtM, MdtL, bicyclomycin resistance protein (also called sulfonamide resistance protein), and the uncharacterized inner membrane transport protein YdhC. EmrD is a proton-dependent secondary transporter, first identified as an efflux pump for uncouplers of oxidative phosphorylation. It expels a range of drug molecules and amphipathic compounds across the inner membrane of E. coli. Similarly, MdfA is a secondary multidrug transporter that exports a broad spectrum of structurally and electrically dissimilar toxic compounds. These MDR transporters are drug/H+ antiporters (DHA) belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	0.00492103
NZ_CP011271.1\|WP_162271821.1\|5707688_5708300_+\|repressor-LexA	gnl\|CDD\|234688	PRK00215, PRK00215, transcriptional repressor LexA.	1.01515e-48
NZ_CP011271.1\|WP_082841199.1\|5710108_5712052_+\|PAS-domain-containing-hybrid-sensor-histidine-kinase/response-regulator	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	3.2866e-127

>NZ_CP011271.1|WP_052552667.1|5701692_5702463_-|hypothetical-protein
MPDASVPTVRLGNLTFHLPFAGLLRPLSPLELTELRTSISRHNKVLNRAVTYDSATWGTRCVIDGANRLQIAAELDLDVPVQHRGAMPDEDARAECLDLNLARRHLTVEELEAARTGRILRVMAAKEEGQSTRAIARAEGVSQTQILRDLAVAAAPAPTFAPVPETDVSHDDQSVPEPDPARPLAVMQRSFRQIMYLSKSAKSGALPELLAGPLGGHLSRIAARHGVPLAGDRWPALEVLVAVVSDLAAEAAQGWE
>NZ_CP011271.1|WP_052552665.1|5699916_5701491_+|hypothetical-protein
MDSPFGLRSRISRLLTAPVREPRRAPRARLMAEALEAREVPARVNFTFALDESAGSFGLTTTQRNLFLTDLQAAGQLWSDQIAGAAANPVTLEVRVVPAALGSSTYANCGPTAQVVSGGVSEAGTLYESRTGVDPNGAVSDITMTFNTAYLQSSASFPVGAFFDPSGAARTGTVPAGQADVISVALHEMGHGLGIVSARNSSGVVPPGVAPTTFDTKISGTAFVGAQAQVVNGGAVPLSADYSHLNVSGDLMFPSIGGGVRRSIGGLDTAVLRDLGWAPVITATAATASATFSLDSAGNLFRQAGGTTTLVALAITDMEVVQGQLFVRNGGNNVFRYNAAGGFDFIAASVLQIGQGLNQFFVLNGGNNVYRYNWSTGGFDLLASAVLEIGQGQGQFFVRNGGNNVFRYNAAGGFDLLASAVVKIGSSQGDFLVLNGGNNVYRYNGSTGGFDLIATSVLEMESSQGQVFVRNSGNAVYRYSGGGFALSTVNIIDIWSSGGLFYVKRSDGAIFRYSPGLGDYILSA
>NZ_CP011271.1|WP_052552663.1|5698812_5699148_-|hypothetical-protein
MRASLLTAAAAAALTFTLGTANDAKAQIIVYPSVNSSPYVTPVGYTYPSYSYNYAYNYPGLRTYSYGWTNPYSTWQWAGYRTYPTYPAYYGGYTGYYGGPRYYGGWRGRRW
>NZ_CP011271.1|WP_082841193.1|5698297_5698633_+|ribosomal-subunit-interface-protein
MHVEVNTDTRTSVDATAATTRIENGLARYRERLTRVEAHLSDVNGPKGGHDIRCALEARPAGHQPLAVTNEAHTPEDSVKGAVEKMGRLLEHTFGRIDDAKGHTSASGLPT
>NZ_CP011271.1|WP_082841192.1|5697283_5697895_+|hypothetical-protein
MMRLIVALFASGALIGLAPAAPVPKHLMPKEPLYYSVQKGTRWVYTDNGMDCEFEATDVKPLARDGWTVTVECVRDGAKSPYQKIEVSPRGLVVIEARGISAENPLCLLQRPAEPNAEWSYRRDNPGATYSRGAMMVTGTEDVKVPAGVFRAVRVVHEVTVVWNDKPIQQLRVTTWYAPDVGLVKATGEGYKSELKSFTPGKG
>NZ_CP011271.1|WP_082841191.1|5696133_5697090_+|DUF1559-domain-containing-protein
MTEPNRSLRRRGVSLVEVLVVLSLLSFLFALLIPAVQSARAAAARISCRSNLRQIALATHSYESAHGQLPPAFRHRRTDAETPNLQWPLLIAPYLELGANWQTAVDDFRRDRDAIFPTPHRGLSVPLKPFSCPSDPRTAVSWEVKFVYTLARPRPTLVTRSFALNSYLGNGGEFSARRDGVIVADGTVTLLHVTDGTSNTLAFGERPPPRNLMLGWLYYGWGAHANGVGELSSVMGVNDPNPFARRVPDTSCGPGPFPYQQPDLNSEADCAQFQYWSLHSGGANFAFCDGSVRFLTYRANSVLAALATSAGGEVVAPD
>NZ_CP011271.1|WP_082841190.1|5695018_5696137_+|hypothetical-protein
MEFASLIFLVLSPGAPTDKAEAVVAQKSRMPNRYQLKLRVESRTPNAPPPLESSWDSTLHIWRDGNKLRVDHLDAHYTPPRPNHDSHDRRITCENCEREGYGIVTTVVRGAPPTLHAVEFVRLGTRNLDGYCTFFDWRYFGLSNDRMCGYSRLHIGTDFPGFFGRPEVQTRNENRDGVPCLVATMSRKTANLQQSVWLSERDGFHPIFFEDKFEVEGKPESRTAEVSWQLTPGGHRYPKTMKHDTTISFNGAKYRSEEVVTVTHADFDSAIDPAVFTLAGFGLNENQAIRLPDLEPSKLPLWRNGKVDESYTLGQYTADMLGPPTAVADGPKTVASYPTEGNTTLIVSFVAALLATVAAVLAVVIRRRRAAG
>NZ_CP011271.1|WP_157469754.1|5693917_5694589_+|hypothetical-protein
MNELPEELPEELPEELPEDLPPPPPARPGLILAAGGLWVLVGAFFLLMTCLGTVLDILLEAGRQGPVRNSTAGCAMQVNMLIWGGFLTAGIRTLQGKAKDTIITSVMSILVGLLYFVIGAVSLWLAGGPGRAPGPFVTAMLVTGALSVLLGGALFLPAVLALAARSQYLEWREALEPPRRRRTRRRREEQDEERDWERPKYPRDPKRPWNRARRDSDDDDSWG
>NZ_CP011271.1|WP_157469753.1|5692437_5693580_-|TIGR02996-domain-containing-protein
MSTPDRHPDETAFLAAIAAAPDDATARLVFADWLEERSDPRAAWVRDADIWEWMKPDARDPVPGILKTLTVLRPGVRSSIEREKINWKRRGSAEAALFEMGTSAVDAVRTWIREHPDQVPGEAVQIFMRCSKPDKLQSVLTLQTKLDAQSWVDVWLAVVDLGFHKAAAAPSVTALTEIEGWKRWPEFNDSMDSVERPVENAICYTLGQIGPAALEAVRWLASNMWLYPESAAEALIQLRADPDLIVEHINTDEDHEVQSGIRSILELASDPVAFLVRNAQQRTGRVAYTSLRLLAEMGQKLLLPCPHSGISSTTEPNGIRTTSATRRTWRFRRSTQRTDPRHRHLVPTSPAGSHRPFARHLRRPRAENERRVAFRLLVRA
>NZ_CP011271.1|WP_082841188.1|5691012_5692389_-|Gfo/Idh/MocA-family-oxidoreductase
MDRRHFLRTSSAAALAVPAGGYFVVGAEPKPLRVGLVGTGWYGKCSLFRLLQVAPVEVVALCDVDKKMLAEAADLITARAKAPKKPRLHADYRELLKEKDCDVVMVETPDHWHALPAIAAMEAGADVWVQKPVSVDVLEGKAMLDAARKHKKVVQVVTQRRSTPHLVDAKEKVIKEGKLGTVGHVEICCYYHMRSGDKPPVTKVPEFFDYEMWTGPAPLREYDAPFYKDLDANLPHRRWWRAFTEYGNGIVGDMCIHMLDMVRWMLDLGWPTRVSSTGGILVQKNAKSNISDTQSATFEFPSLTVTWQHRTWGSTPDPEYPWAAFIYGDRGTLKASVNKYEFFPQGSNRPTVTGTALFEEDKFPEDKTEKDLERHVASALRRHWQDFLKARESRGKPVADIEQGHISSASCILANLSQQLGRSITWNPEKHICVGDDEATKLLKRPYRAPWKHPADAV
>NZ_CP011271.1|WP_082841195.1|5706610_5706847_-|hypothetical-protein
MSQRATSNRCNHPRVLVCVDPNGTEIWRCPVCVTDRVVHWAPPRFDPPATFRERPCHDDEDDPAFENAVRALEDALRD
>NZ_CP011271.1|WP_157469755.1|5707027_5707186_-|hypothetical-protein
MDEYQRKITKLLDEAADDLGADDFDELLDTITDEIIERQDMSEDGADDFDDE
>NZ_CP011271.1|WP_052552672.1|5707248_5707497_-|hypothetical-protein
MAKRSRIEIGRAILRLAADGELRPLADLSGAAGAPPVVMLRWVIEGRRGAHLDGVKRRGEWWTTPAAVARFLKASAPADAPA
>NZ_CP011271.1|WP_162271821.1|5707688_5708300_+|repressor-LexA
MAEREPLSPSQAKLLEFLRAELRARRGVPSWPKIARACGWSSTRSVGYNLDQLARRGHLRLTGGPGGIELVGAPAGFTLPVLGDVAAGAPIPPPGDGEPEHFEFERVFGGEDVFMLRVRGDSMIEALIGPGDLVAVRRAPEAADGEKVVAMIDGELTLKVFRQRAGGAIWLQPCNSKLAGIKLDPKKDNRVIGVLVGVVRAGN
>NZ_CP011271.1|WP_162271822.1|5708479_5708902_+|hypothetical-protein
MWCALLALVLSVCPVLSQKPRPDRVARIKVDGNVHTPDSVILNELYALGLYPGRLLNRAKLPIAQTRLKKLGLFEDVTVAVIDNEFDSEYKDILIQIQERSWVWLTFAVEDTTIAVLTLDVDLYRSTAYRVQKKLWGQSP
>NZ_CP011271.1|WP_082841198.1|5708963_5709677_+|MOSC-domain-containing-protein
MTGPVLVSVQVGGPQTFGEEGAADPADRPWTTGFIKAPVTGPVALRRTNLSGDGQADLVNHGGPDKAVCVYPEVHYAYWRADLNRDELPPGAFGENFTVGALAEPDVCIGDVWKVGAAVLQVSQPRQPCWKLARRWRVKDLALRVQQTGFTGWYFRVLQEGVVEAGLPLELVERPEPHWTVERANRVMHHLKSDYAQAAELAALPTLSASWKNTLRTRAEKHTHPDAGKRLNDPHAN
>NZ_CP011271.1|WP_082841199.1|5710108_5712052_+|PAS-domain-containing-hybrid-sensor-histidine-kinase/response-regulator
MNGTGESLPVPASLTVHTAVEGLLLLFNAVEDYAVFVMDTSGRVTVWHPCAQRLLGYAAEEIIGADFARLFPPEDVAREAPRRQLDAAARSGRADEEGWRVRKDGTRFWAFTSVSAMRDRTGGIWAFGQIVRDLTERRRAETLFRSVIDNADDCIITSDVTGRILLFNRAAERTFGYAASEVVGHNVRVLMPEPFRGQHDSYIEHYVRTGQARILGAGREVVGLRKNGSEFPLHLEVSQFTLDDQRHFIGIVRDLSASKRLEDQLRQSQKMEAVGRLAGGVAHDFNNLLTIINGYSEVLMGAMPAGDPNREWVRVVWEAGNRAAGVTRQLLAFSRRTIVEPRVLDLNEVVALSTKMLKPLIGEDVIVSTVLAPDLAHVRADRNQIEQILVNLAVNARDAMPGGGRLSIETRDVRLGAPGSVAYPELQPGRYAQLTVTDTGAGMTAEVRANIFEPFFTTKESGKGTGLGLAMVYGAVKAHGGHIDVSSAIGTGTTFTILLPATTETGAEGDGTAPALPLAARGTETLLLVEDEDGVRHLAKFVLESHGYTVIEARDGREAVALAGAHAGPIHLMVTDVVMPGLGGREASETVRAARPDLKVLFMSGYTDDEVVRHGIVEATGAFLQKPFSPLGLARKVRAVLDSAPDS
>NZ_CP011271.1|WP_082841200.1|5712140_5712587_-|TIGR03067-domain-containing-protein
MSHRVALLCTALVVAVFAPARAADEKDDKKATQGTWAYETLEWNGKKIPFNQIKMTTVTFDGDKFAIKIGDKVTSSGTHKFDSTKSPKTFDATVTEGEGRGTTMLGIYKLDGDNLTGCINLTGRERPTEFKTTENSETVLMTAKRAKK
>NZ_CP011271.1|WP_082841201.1|5713728_5714160_+|terminase-small-subunit
MLSARHETFCLEYVIDLNGSAAYQRAYPKAKTAGAARTGAARLLANVSVRERVAELQLARAERADTTHEWVLERLKQEAEFEGQGASHAARVSALALIAKHLGMFKPVPVPDRPPIDLSKIPDDLKRALLAGLRAVRGPGAPG
>NZ_CP011271.1|WP_082843396.1|5714143_5715658_+|hypothetical-protein
MGLRAKDLPLLEPDLERWDASTLTPAQWNARFLPHYFGTYPPALLHRDFDADLHNLHLARGTRRSIIAPRGAAKSTWKTLAYPLRCALEGWEPYVAILSDCSTQANNQLRHIRLELETNQRLASVYRTACAPGAEWNESKLRLKNGAVIEAFGTGKKIRGHRNRSARPSLIIFDDVQSNADIRSAELRQHAWDWATRDVLPAGDERTNYLAVGSALHRESVAVRLGQLAGWTGRTYRAVLSWPERADLWDEFERLATNLADGNKLETARAFYARNKPEMDRGAEVYWPDRFPIVELMLKRAEVGATAFESEYQGVPGVPEGAEWPAEYFDRTDFFFDSWPADLVFKIQSLDPSKGTSEKSDYQAHVLLGLSQFGTLFADCELRRESGWVERAIDIAAAWRPEELIAEVNNTMGLFTPAAEQLLRERHTQGRPVALKYTETIVSRPKPVRIRALNDYLRRGQLRVKNTPGGRLLAEQLRDFPHGAHDDGPDALATAVLRMQELVT

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Crispr_ID: NZ_CP011271_18

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_18

5835070-5835171

Orphan

Consensus_repeat	Method
ACCGCGGCGTGCGCGACGCGGCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_18

>merge|NZ_CP011271|18|5835070-5835171|CRISPRCasFinder
ACCGCGGCGTGCGCGACGCGGCGGCGGCCCGCCGGTTCCTCGATACGCCGCTCGGGGGGCTACTCCCGCCGATGGCGCTACCCGGCGTGCGCGACGCGGCGG

>NZ_CP011271|18|18|5835070-5835171|CRISPRCasFinder
ACCGCGGCGTGCGCGACGCGGCGG	CGGCCCGCCGGTTCCTCGATACGCCGCTCGGGGGGCTACTCCCGCCGATGGCGC
TACCCGGCGTGCGCGACGCGGCGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_052552871.1\|5821975_5822305_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380358
NZ_CP011271.1\|WP_082841283.1\|5849131_5850535_+\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP011271.1\|WP_157469782.1\|5834135_5834669_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841278.1\|5836916_5838659_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|293787
NZ_CP011271.1\|WP_162271827.1\|5842271_5842811_-\|DUF2721-domain-containing-protein	unknown	unknown	gnl\|CDD\|378544
NZ_CP011271.1\|WP_082841274.1\|5823772_5826529_-\|peptidase	unknown	unknown	gnl\|CDD\|349459
NZ_CP011271.1\|WP_162271826.1\|5822652_5823291_-\|LamG-domain-containing-protein	unknown	unknown	gnl\|CDD\|379155
NZ_CP011271.1\|WP_082841281.1\|5846793_5847210_-\|response-regulator	unknown	unknown	gnl\|CDD\|381118
NZ_CP011271.1\|WP_052552900.1\|5844362_5845265_-\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NZ_CP011271.1\|WP_082841280.1\|5839272_5842266_+\|c-type-cytochrome	unknown	unknown	gnl\|CDD\|274225
NZ_CP011271.1\|WP_052552901.1\|5845283_5846219_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052552876.1\|5829779_5830826_+\|GlxA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|227311
NZ_CP011271.1\|WP_082841276.1\|5830940_5831642_+\|DJ-1/PfpI-family-protein	unknown	unknown	gnl\|CDD\|153233
NZ_CP011271.1\|WP_082841275.1\|5826682_5829493_-\|S9-family-peptidase	unknown	unknown	gnl\|CDD\|224423
NZ_CP011271.1\|WP_052552895.1\|5842917_5844357_+\|amidohydrolase	unknown	unknown	gnl\|CDD\|349922
NZ_CP011271.1\|WP_082841279.1\|5838655_5839162_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052552881.1\|5833405_5833981_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NZ_CP011271.1\|WP_052552880.1\|5832282_5833260_+\|TIGR02996-domain-containing-protein	unknown	unknown	gnl\|CDD\|274381
NZ_CP011271.1\|WP_082841282.1\|5847737_5848886_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052552869.1\|5821745_5821946_+\|DUF542-domain-containg-protein	unknown	unknown	gnl\|CDD\|377347

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_052552871.1\|5821975_5822305_+\|cupin-domain-containing-protein	gnl\|CDD\|380358	cd02230, cupin_HP0902-like, Helicobacter pylori HP0902 and related proteins, cupin domain. This family includes prokaryotic and archaeal proteins homologous to HP0902, a functionally uncharacterized protein from Helicobacter pylori and Spy1581, a protein of unknown function from Streptococcus pyogenes. These proteins demonstrate all-beta cupin folds that cannot bind metal ions due to the absence of a metal-binding histidine that is conserved in many metallo-cupins. HP0902 is able to bind bacterial endotoxin lipopolysaccharides (LPS) through its surface-exposed loops, where metal-binding sites are usually found in other metallo-cupins, and thus may have a putative role in H. pylori pathogenicity.	5.92707e-28
NZ_CP011271.1\|WP_082841283.1\|5849131_5850535_+\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.15919e-72
NZ_CP011271.1\|WP_082841278.1\|5836916_5838659_-\|hypothetical-protein	gnl\|CDD\|293787	sd00044, HEAT, HEAT repeats. The canonical HEAT repeat consists of two helices forming a helical hairpin. HEAT repeats are found in a diverse family of proteins, including the four proteins from which its name is based: Huntingtin, Elongation factor 3, the PR65/A subunit of protein phosphatase 2A (PP2A), and the lipid kinase TOR (target of rapamycin). The HEAT repeat family is related to armadillo (ARM)/beta-catenin-like repeats.	0.00241838
NZ_CP011271.1\|WP_162271827.1\|5842271_5842811_-\|DUF2721-domain-containing-protein	gnl\|CDD\|378544	pfam11026, DUF2721, Protein of unknown function (DUF2721). This family is conserved in bacteria. The function is not known.	3.46126e-18
NZ_CP011271.1\|WP_082841274.1\|5823772_5826529_-\|peptidase	gnl\|CDD\|349459	cd06240, M14-like, Peptidase M14-like domain; uncharacterized subgroup. Peptidase M14-like domain of a functionally uncharacterized subgroup of the M14 family of metallocarboxypeptidases (MCPs). The M14 family are zinc-binding carboxypeptidases (CPs) which hydrolyze single, C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. Two major subfamilies of the M14 family, defined based on sequence and structural homology, are the A/B and N/E subfamilies. Enzymes belonging to the A/B subfamily are normally synthesized as inactive precursors containing preceding signal peptide, followed by an N-terminal pro-region linked to the enzyme; these proenzymes are called procarboxypeptidases. The A/B enzymes can be further divided based on their substrate specificity; Carboxypeptidase A-like (CPA-like) enzymes favor hydrophobic residues while carboxypeptidase B-like (CPB-like) enzymes only cleave the basic residues lysine or arginine. The A forms have slightly different specificities, with Carboxypeptidase A1 (CPA1) preferring aliphatic and small aromatic residues, and CPA2 preferring the bulky aromatic side chains. Enzymes belonging to the N/E subfamily enzymes are not produced as inactive precursors and instead rely on their substrate specificity and subcellular compartmentalization to prevent inappropriate cleavages. They contain an extra C-terminal transthyretin-like domain, thought to be involved in folding or formation of oligomers. MCPs can also be classified based on their involvement in specific physiological processes; the pancreatic MCPs participate only in alimentary digestion and include carboxypeptidase A and B (A/B subfamily), while others, namely regulatory MCPs or the N/E subfamily, are involved in more selective reactions, mainly in non-digestive tissues and fluids, acting on blood coagulation/fibrinolysis, inflammation and local anaphylaxis, pro-hormone and neuropeptide processing, cellular response and others. Another MCP subfamily, is that of succinylglutamate desuccinylase /aspartoacylase, which hydrolyzes N-acetyl-L-aspartate (NAA), and deficiency in which is the established cause of Canavan disease. Another subfamily (referred to as subfamily C) includes an exceptional type of activity in the MCP family, that of dipeptidyl-peptidase activity of gamma-glutamyl-(L)-meso-diaminopimelate peptidase I which is involved in bacterial cell wall metabolism.	8.05556e-118
NZ_CP011271.1\|WP_162271826.1\|5822652_5823291_-\|LamG-domain-containing-protein	gnl\|CDD\|379155	pfam13385, Laminin_G_3, Concanavalin A-like lectin/glucanases superfamily. This domain belongs to the Concanavalin A-like lectin/glucanases superfamily.	4.99348e-12
NZ_CP011271.1\|WP_082841281.1\|5846793_5847210_-\|response-regulator	gnl\|CDD\|381118	cd17580, REC_2_DhkD-like, second phosphoacceptor receiver (REC) domain of Dictyostelium discoideum hybrid signal transduction histidine kinase D and similar domains. Dictyostelium discoideum hybrid signal transduction histidine kinase D (DhkD) is a large protein that contains two histidine kinase (HK) and two REC domains on the intracellular side of a single pass transmembrane domain, and extracellular PAS and PAC domains that likely are involved in ligand binding. This model represents the second REC domain and similar domains. DhkD activates the cAMP phosphodiesterase RegA to ensure proper prestalk and prespore patterning, tip formation, and the vertical elongation of the mound into a finger, in Dictyostelium discoideum. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.11559e-20
NZ_CP011271.1\|WP_052552900.1\|5844362_5845265_-\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	9.61718e-38
NZ_CP011271.1\|WP_082841280.1\|5839272_5842266_+\|c-type-cytochrome	gnl\|CDD\|274225	TIGR02604, Piru_Ver_Nterm, putative membrane-bound dehydrogenase domain. All proteins that score above the trusted cutoff score of 45 to this model are large proteins of either Pirellula sp. 1 or Verrucomicrobium spinosum. These proteins all contain, in addition to this domain, several hundred residues of highly variable sequence, and then a well-conserved C-terminal domain (TIGR02603) that features a putative cytochrome c-type heme binding motif CXXCH. The membrane-bound L-sorbosone dehydrogenase from Acetobacter liquefaciens (Gluconacetobacter liquefaciens) (SP\|Q44091) is homologous to this domain but lacks additional sequence regions shared by members of this family and belongs to a different clade of the larger family of homologs. It and its closely related homologs are excluded from the this model by scoring between the trusted (45) and noise (18) cutoffs.	9.98334e-29
NZ_CP011271.1\|WP_052552876.1\|5829779_5830826_+\|GlxA-family-transcriptional-regulator	gnl\|CDD\|227311	COG4977, COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription].	3.04823e-95
NZ_CP011271.1\|WP_082841276.1\|5830940_5831642_+\|DJ-1/PfpI-family-protein	gnl\|CDD\|153233	cd03139, GATase1_PfpI_2, Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. PfpI is an ATP-independent intracellular proteases which may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow.	1.6491e-68
NZ_CP011271.1\|WP_082841275.1\|5826682_5829493_-\|S9-family-peptidase	gnl\|CDD\|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	6.9886e-35
NZ_CP011271.1\|WP_052552895.1\|5842917_5844357_+\|amidohydrolase	gnl\|CDD\|349922	cd05673, M20_Acy1L2_AbgB, M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily. Peptidase M20 family, ACY1L2 aminobenzoyl-glutamate utilization protein B (AbgB) subfamily. This group contains mostly bacterial amidohydrolases, including gene products of abgB that catalyze the cleavage of p-aminobenzoyl-glutamate, a folate catabolite in Escherichia coli, to p-aminobenzoate and glutamate. p-Aminobenzoyl-glutamate is a natural end product of folate catabolism, and its utilization is initiated by the abg region gene product, AbgT, by enabling uptake of its into the cell in a concentration-dependent, saturable manner. It is subsequently cleaved by AbgA and AbgB (sometimes referred to as AbgAB).	2.86273e-176
NZ_CP011271.1\|WP_052552881.1\|5833405_5833981_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	0.00376973
NZ_CP011271.1\|WP_052552880.1\|5832282_5833260_+\|TIGR02996-domain-containing-protein	gnl\|CDD\|274381	TIGR02996, rpt_mate_G_obs, repeat-companion domain TIGR02996. This model describes an abundant paralogous domain of Gemmata obscuriglobus UQM 2246, a member of the Planctomycetes. The domain also occurs, although rarely, in Myxococcus xanthus DK 1622 and related species. Most member proteins have extensive repeats similar to the leucine-rich repeat, or another repeat class or region of low-complexity sequence. This domain is not repeated, and in Gemmata is usually found at the protein N-terminus.	1.51947e-08
NZ_CP011271.1\|WP_052552869.1\|5821745_5821946_+\|DUF542-domain-containg-protein	gnl\|CDD\|377347	pfam04405, ScdA_N, Domain of Unknown function (DUF542). This domain is always found in conjunction with the HHE domain (pfam03794) at the N-terminus.	3.43531e-09

>NZ_CP011271.1|WP_157469782.1|5834135_5834669_-|hypothetical-protein
MTAAFLLMSSAALAGADPVAQPAPATPAPVVVSGAGCSNCGTPACDPCASGKVGLLDKLKARFPKKSHDCCTPAPAPCDPCAGAKPNLLDKLKARWSSKKSHDCCTPACDPCGAAPAAPVTPPTTGGTTPPKEMPKGTTPPKETPKATTPPKGGVSIPLPLPPVTGASGLAGSSNPY
>NZ_CP011271.1|WP_052552881.1|5833405_5833981_-|helix-turn-helix-transcriptional-regulator
MNGASPGLGAELANKIARLVEERGWNQEVFARIARLNRHTVRQILQGGPKRQLRNLTVSQCADALGLTVSELRTLPLERLLPRMHGKPAADEETFDLLYERAQLPELVAWLERNRDRAVELRPDEVQELLDMQAPGGPLVKLGVETCVDLIERRRHLVCRVKEIAGTEYFDFLEQCVKLIHEKVKPPGRRT
>NZ_CP011271.1|WP_052552880.1|5832282_5833260_+|TIGR02996-domain-containing-protein
MSDELALRAAVACAPLERTPRLVYADWLDEHDRPLDGALQRILAEPERDDHRSAYADVCTRIGDGPRAEFVRVQLALANLTPPHQFWPTQIEFDPQDHLCGDHTEGTRPGPRRARVLVGYERFAADPRTVKIGDVIDLVGPVAAAACEQSAELLGARVVGSVVDVEHAGAIKFDVVWGTDHYTDRAELNDLRVRERALMGGPGWEQLLPGPWALAFSNVEHVRAVSGSVLAAGARRGFITMVSGPASEWLVHGDAICARHPVEVVRLRTLPNIEADDHGTAFEARLLGRPRWRSFDKARAVTIQQVVLELLASEWPGVTFEFAGN
>NZ_CP011271.1|WP_082841276.1|5830940_5831642_+|DJ-1/PfpI-family-protein
MADHLNVGMLVFPRMDQVDLTGPFAVLSRLPNASVQLLWKDTKPVRDYRGLGLMPDARLTEAEPVDLLVVPGGPGQEDLMEDEGVLSFITQQAARAKCVFSVCTGALVCGAAGLLKGRSATTHWRSVHLLKYFGAVAKDQRVVVDGTFVSAAGLTAGIDGALRVAELLRGSDSAKAIQLDLQYAPEPPFDCGHPDKAPAELVAKLKGATEKLTAQRLVTAKRAAARLKVPVED
>NZ_CP011271.1|WP_052552876.1|5829779_5830826_+|GlxA-family-transcriptional-regulator
MGNRNRLAHRSRAPRKIVVLAFPQAKLLDVTGPCEVFADANRALGRSAYSVELVSNAAGPIETSSGVQLVAHRGFTGGRGPIDTLLVSGGPGIDRAMQEVALLRWLARCAARTRRLGSICTGAFLLAAAGLLDGRRATTHWAFCDRLAREFPRVRVEPDPIFVRDGNVYTSAGVTAGMDLALALIEEDLGRDVALSVARNLVLFVRRPGGQSQFSTSLELQAADREPLRDLQTWAVEHLADDLSVGALAQRTHMSVRNFSRIFRRETGHTPARFVERLRVEGARRRLEESGAGLEQIARECGFGCADSMRRSFLRVLRVAPSDYRTRFRGAEEQAPAPRSRPQIETED
>NZ_CP011271.1|WP_082841275.1|5826682_5829493_-|S9-family-peptidase
MRGNRFLRRSAACVGLVALAGLLRAAEPAPAPRPAGAAATLAPLGRETYLLPPKEIADAVLASRGEIVALTNLSPDGRKFLIAKRDPLPSVERLGAPCVHLAEMAFDPVACRSRELWVGSAEALDLFFPAERRTVPVRVPSGARIASPAWSPDGSKLAFFALFPDATHICVADTETGACRKVTQTPVLATLVTAFQWSPDGKRIHTVLLPDGGKRPVPKPGIATEPKVRIARDGKDPSRTYRYLLESPYQMQLLEHLLTGQVAIVGVEDGAVTPIGEPAMVRSVSASPNEKQFRVATVKKPFSYYAPFQRFGSQESIWNVSGKVLVTLSDRNLRETETPPVVTPATTPTQPPFPKGGLTKGARGTGGTQPVPDPTQPAPTPPVNPMNPDDAPTVAPEPFDPDAKRDLSWRPDGKGMSFLQLEPAAKDAKKDDTKKDDAKAVRKDRVMQWLPPFGKDDAKVVYESPNRIVGAQYSADGHWLFISQTVDAQRQITAIDLANTKTTYVISRGGSDFAAPKKDEPPAKKDGDSDNEDADTEQPGAGRGGATVGLGLLARPLGAVNVVRVSIAGTVYLSGTERARGAGEGAFPKPYIDAVTIKTGKKTRVFEGKADVLETVDGVDGDDVKYVFTTRQKSNVVPNSYVTDIATGKATKLTDNVEKSAWFHELKTERFRATRADGIKFWVKVTRAPKAEGKLPALFWIYPREYADQADYDAKAGRGGTGTGPGATAGRYTGPAPRSVAILTLAGYAVVEPDVPIVGPAGRMNDNYVPDLRNGLWAAIDECDKRGIIDRDRLACGGHSYGAFSTANALAHTPFFKAGIAGDGCYNRTLTSMSFQSERRQLWDARETYLEMSPLLRANQINGALLMYHGMEDANVGTHPMNSEALFAALDGLGKPAALYMYPYEGHGPIARETNLDMWARWLAWLDLYVKNTKAK
>NZ_CP011271.1|WP_082841274.1|5823772_5826529_-|peptidase
MASRLLVPLALAIGTAFLYPGGAARAAEPVAPKVTTPKAHFGFNLGDDYCLANYEQYAAYLAKLAKESDRIKVVDIGRTEERRPQLMAVVTSPANHKLLSRYQTIARDLANADGITSEAAKKLAAEGKAVVWIDGGLHASEVLCAQAVAETVYQMVSGTDPETLRVLDDVIILFVHANPDGHDLVADWYMRDKDPKKRSLGGLPRLYQKYIGHDNNRDFYANTQAETRNMNRVMYREWLPQIVYNHHQTGPPGTVLFCPPFRDPFNYNFDPLVVSGIDAVGAAMMQRFLAEDKPGATTRSGARYSTWFNGGLRTTAYFHNMIGLLTETIGSPTPIRVPFNPALQLPKADLLSPVAPQEWHFRRSVEYSVTANKAVFDYASRHREQLLYNIWLMGKNATERGNRDSWTVTPKMVAAAKGARGADGFQKFFRDPAKRDARGYVVPADQPDFLTATKFVNALIGTGVRVHRATSAFEVAGKKYPAGSYVVKSAQAVRAHVLDMFEPQDHPDDFAYPGAPPTPPYDAAGYTLAFQMGVQFDRLLESFTGPFEELKDEVPPPPAKVLDANGAVGFFLRSSTNDAFRAVNQLLAAGEEVRRLKEPCTVDGAKHPAGMFFVVKKDGTQERLEKIARALGTRFVGSTEAPGKEAGTLKPVRVALVDRYGGSMPSGWTRWLFEQFEFPFTVVYPPDLDRGGLRDKFDVIVIVDGLGGGRGGGSGGGGGGDQPPEPNAVDELALPAEFRGRRGSITTTKTVPELKKFVTAGGTLLTIGSSTSLANQLGLKIESHLIETGTDGKEKPLGRDKFYVPPSVLRAKVDPAHPLAWGMSDEVDVMFANSPTFRFPTGAAASGLTRVSWFAGKSPLRSGWAFGQEYLDGGTAVIDAAVGKGRVVLYGPQVLYRAQPHATFKLVFNAIVRAGQNE
>NZ_CP011271.1|WP_162271826.1|5822652_5823291_-|LamG-domain-containing-protein
MPSFPLKVPGEPMPFVADGVMHFDGRTRTVTPVQRFAPCTLEAWVWPEEYRDTGTQAVIGSDIPTKYGIGLGITGVVPFVEIVPGILKGTQPVPLRKWSHLAGVFSEEGTRLYLDGKLVTKGPATRAEGGTKFVIGNIGLGNPIDYFKGKVRAVRINQGERYADAFIPVEQLLPDATTVLLYTAESVRGDVVNDFSGKGHHGRVERGFASPP
>NZ_CP011271.1|WP_052552871.1|5821975_5822305_+|cupin-domain-containing-protein
MAIPHAQPGDVIDVRPLGPALATAKTTTLFKADRLEVIRLVMAAGKELAEHNAPGEITVHCLEGKIAFTALGKTQELTAGRVLYLGGGEPHSVRCLEDASFLLTLVRPP
>NZ_CP011271.1|WP_052552869.1|5821745_5821946_+|DUF542-domain-containg-protein
MTPCDLDTSVPDWIIDHPQTLAVFEALGIDCSCGGKSLGYACRVRGLDAEAVLAKLRQCLSDHEPI
>NZ_CP011271.1|WP_082841278.1|5836916_5838659_-|hypothetical-protein
MKRYSATTTWAARFALFGIAAAMLAFLTVGVYMALPHQPPKPPETTPGYSFAQLTPEETLPVKPKTPEGPAKPGDPIPIEPKPKVVDVSEALALAAGGVVGEVAATKSNDPGPGLADPVSTPDTAVREIGRVETSRTLVVTQDPAKPGVWSRLRVKGDGDEIVVSNAPVMALPGYKANVLIGARDKQVQVYLWGNVPEQIPYRVFESRVKFHPPAAGFDADLTLLGGRIYLKSKKPEGDKNPASRKVRVRAANEVWDISLPDEKTDVLVELISWFEPGTTYARAGGAPPKQEGRVAVLNGAAKFAAPRRFKAVDKFAVNTQIVWDSGSGALADPQPITNMQEATANPTLDGDDQKNISRIFTETADRVTERNVVRQVIESRLDPPPTVVDREAVARLTVYSLAALADNSPPGDEMLKALVDVLKSELPWFVRQSVVTALTAWVARDRGNTAILRAVLVSKGLGEDKDDEDAADRFLRLIRGFVSPTKPDPERLDELGKLLADKSIPVREAALWNIASVDLETWVPPPARANVGAVGAAVNSEDYKKFLVTWRGKIEMLKKRTTPFPLPRPVPKDGKEGKG
>NZ_CP011271.1|WP_082841279.1|5838655_5839162_-|hypothetical-protein
MPRLTLRTLLAYIDDTLNPTETRSLGRKVAASDEARELVERIKKVTRRRGLKTPVPTDADDETADPNTVAEYLDNTLDSDTLKQLEETCLASDVHLAEVAACHQILTLVLTEPVRVPPRAHRRMYGLQSAPAATPGRRPNKKLPVGGVRTPERDRGSTTTRTRRCSSV
>NZ_CP011271.1|WP_082841280.1|5839272_5842266_+|c-type-cytochrome
MTVVLLLLSAVATPPASVTDLKLAPGFSAKLFADNPIAPDVYTMTIDDAGRVLIAGRGYVRILVDDDNDSYADRAIDLIDGLKDGPMGLFAEGDSLFVVGDGGLKRYRGYNGRNKLKGPPETILALKTAGEHDAHAVRRGPDGWLYLLCGNMSGVRKSTITGSRSPVRDPIAGALVRISPDFKNVEVVADGFRNPYSFDFNRDGEPFTYDSDNERCVGLPWYEPCRLYHVVPGGNYGWRSPQLSQTWRKPPHFPDVVAPICTLGRGSPTGVACYLHTQFPEKYRGGFFLADWTFGRIHYVPLTANHSTYTGRPEVFAEASGTSGFAPTALAVHPKTGELFVSIGGRGTRGGVYRIAFDKGDANPKPLPTTKRSLEFDKTSADQWIKDTEPKSEHAAEDTRKRRHALEMVVRYHEKIPRSEALNNAVKSNLTATDPLTRAAAARAAVVLTVPVGEVPNTKPPTAEQLAVALVVAADEPAWALKVALGVLDNTNATSGELIAALRIVHLAHGDLTAKDAVGTVWEGYTLRNEIPRALAHQLHDILAKRVRKFSEGPRTVDLEFARLFAILGGEFDPPARRATLDRMRKDSDPIDDFHYLIAAARTSSKTTSQETGELATALLGLQQKVKSRGVTLDRHWPLRFDEILTRFGGNWHKLNEAVVDHREFGRPEHAALVRPLKLNADDATRRFILSAAADKRYAWTPAVVEFLARMPRTDVDRLLRDLWERPGLEDAVLRVLAHDPRDADCPKFIVGLKAFDPSLVRASANALAKSSATDAKEVCVAAIRALRRFPDAKTDATTRTALFGLLQKFTGEKLEPTEKAWVAWFVKQHPDAAKALDAGDGFDTTAWQKRAANIAWAKGDAERGRAAFTKATCAACHDGGRAVGPSLLGITKRFGRDDLLTAILQPNKDVPPRYRPVRVTTTDDTSYTGIIVYEATDGVILQTGADTTVRIAGADIASKKPVDVSLMPAGLLDKLTDAEIADLLAYLGTLAEPVPK
>NZ_CP011271.1|WP_162271827.1|5842271_5842811_-|DUF2721-domain-containing-protein
MAITFLGAGEILGAMITPAVLISASGTLVLSTSNRLGRVVDRIRALATEAEGLPDVSAAPEIVEKRILIAEQIEFLTTRLLMLQSAVITLYTAIGLLVGASLAVGLSASAGRMMEWVPIGFGLMGASALLFGASVLVRESRLAVRGTLHELAHVRKVVERKTSMRAAPDEKPEGGQGEG
>NZ_CP011271.1|WP_052552895.1|5842917_5844357_+|amidohydrolase
MRLLSLLALLAFPALALAQKDAAIKSAAAHADVNWPAALKIWNWAEPGYQEKKSAEELAAIAEKAGFKVTKGVAKIPTAFTAEFGSGKPVIGILGEFDALPELSQEAVPFRSPRKDGNGYGHACGHHLFGTASLAASIAIAEQIKAGKLKGTIRFYMCPAEEGGAAKVFMTRAGLFDDCDTVLHWHPGARNSAGDASCLARIAVKFRFHGTPAHAAGSPEKGRSALDALVLTMHGVELLREHTPDGTRLHHTVTSGGGAANVVPEFAEGFFYVRHPKADVVQKLYPRVLKCAQAGALATETKLEVAYLGGTMEILPNDTLAQVAKKNLTALNDLKYDDTETKFALRLRETFPDKAPPLEEIERVFDVSGKSSGGSTDVGDVSWVVPVVGFGTACWVPGTPGHSWQAVACGGTTIAKKGMNLAARTLAATAYDLFTDADLRAAAKAELTKRLDGRKYAAMLEKDQPPPLDYRDSKRKSGE
>NZ_CP011271.1|WP_052552900.1|5844362_5845265_-|DUF1559-domain-containing-protein
MLHARSRRCGFTLIELLVVIAIISILIGLLLPAVQKAREAANRAKCQNNLKQIGLGCHLYENGRGYFPPTRYRGETQTWAWFILPQLEQDNLYRKWPEDGNSIGIGQLLDPGFLNTPVPVYFCPSRRTPGQNTAKGFVQPPGCAFPNSVGGAVADYAAAIGTTGDDGADRMGNDQGLVVPPTGAFVALRGVRVAEFTDGTSCTLLVGEKHIPKGFSASYPWDCNTYDGHNSVCSTRTAGPGFPIATADTDSRLIFGGPHIGICQFAFVDGGVRSVRSGIDELTLGLLSHRSDGQPVPTDY
>NZ_CP011271.1|WP_052552901.1|5845283_5846219_-|hypothetical-protein
MAPTETAIATEPPPVVAPAPGPAFRVAENPEPSEEILDGKSGPVLIGVAACFLAAAALATASFQSTAAFARPLAGVGVLVGLVGALAAGAENLSRLAAPIGGTSVSGLALVVAWFLPSLLGPGYEASRVTSDYDPEAIRAIPLQLVSSGAEELGPGGYADASRSALHQGLVRVQITGATVAPVQVVDSKKRFTKQSFLAITVRVQHLGHGDRFRFVHWDTTGERPVPAASATTDGRKLIAANTGQDVPAGVTFGYDVFPGKSVDDQLLFEAPDAVGPVRVELPAEAWGGRGVLRFQIPSSMIVVQPGKKPR
>NZ_CP011271.1|WP_082841281.1|5846793_5847210_-|response-regulator
MTATDLVHRPLGGARVLVAEGDADDSVVLTAVLRLNGFDACEARTAEDALKAASDTRPAVLMVDLDLPDLDGCALIRRVRRLPDPPAVVVVTGHTAESVRRAALAAGASAFLLKPADPIELTKLVGQLSDEQLGRKTG
>NZ_CP011271.1|WP_082841282.1|5847737_5848886_+|hypothetical-protein
MSPAYLSTALAITVGVTALFGCHEPSTPTPTDVTPATTVAESTAAKVFEERIAPIFKSPDPSSCTRCHLATVDIKQYILPSATDTFLALREQGLIDLDKPENSKILALINRGADDPKAAGLISAKRQKAEYEAFAAWIKACASDPALHNAPKPEKMPALATKPVEVVRHARKDRMLESFETNIWSLRFRCMNYHTEGTPQNDKLVKEYGERVAWFRKAGPEATMDYLLASKLLDLDKPEKSLLLTKPLNEVKHGGGVKIVVGDQGYKAIRAWAEDVAAIKKGKYAAATDLPTKEVAPKQFGTEAWFRLNNTPAAWNGKLLQVDVHAWDAKTGAWEKDPIATSDRACGDKGWQHTVTLLAAPGSDRAKSWAKVSLPSRRGNIW
>NZ_CP011271.1|WP_082841283.1|5849131_5850535_+|serine/threonine-protein-kinase
MRTLSDLANVLIGCRIVNRTRWERAARAGGGDPGATLDALTAHPPDWYTATPGDTGEVPPGLSEYQRGVIDLWLEGDQTPIERQLTVNQFLLLEKLGEGGQGEVYRGRQLNPPRFVAIKTLTRDTETSRARFEQEARAMMKIQHPSVARFYLYERVRDEDNKPTNEYLIAMELVDGNDLHRMVRWSGPIPWQFAVKWGIDLLGGLAVIHQNGFIHRDVKPANVIPLGPPPEAGTRPNETAAKLLDFGAVGTVEGAAVSRSGRRVFVGTREYAPPEQWAERVVPASDLYALGGTLFYALTGRPPYEVEGRDAVAFMKAHSRAPIPLATDFNSNVPEKLSWLLQRMLAKRADDRGTAVELIEEFRELLPVNDAPAKPVKSARKSKSAQPAPIPARRPLASSETEAQGALDRVFGPVLTIFERVFLPSRLRPTPGTAHPFGERIASLIRQPIVLLVFVLIAALFVFWIVW

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Crispr_ID: NZ_CP011271_19

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_19

6489590-6489664

Orphan

Consensus_repeat	Method
CCCCCCTCCCTGAAGGGAAGGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_19

>merge|NZ_CP011271|19|6489590-6489664|CRISPRCasFinder
CCCCCCTCCCTGAAGGGAAGGGGGCGTTTGGGGCCGAACCTACCTCCCCATCCCCCCTCCCTGAAGGAAAGGGGG

>NZ_CP011271|19|19|6489590-6489664|CRISPRCasFinder
CCCCCCTCCCTGAAGGGAAGGGGG	CGTTTGGGGCCGAACCTACCTCCCCAT
CCCCCCTCCCTGAAGGAAAGGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_162271857.1\|6481509_6482622_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377450
NZ_CP011271.1\|WP_082841643.1\|6479146_6481384_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223559
NZ_CP011271.1\|WP_082841642.1\|6478172_6478889_-\|arginyltransferase	unknown	unknown	gnl\|CDD\|234939
NZ_CP011271.1\|WP_052561951.1\|6490174_6491128_+\|HDOD-domain-containing-protein	unknown	unknown	gnl\|CDD\|370050
NZ_CP011271.1\|WP_082841646.1\|6485687_6486878_+\|exo-alpha-sialidase	unknown	unknown	gnl\|CDD\|271234
NZ_CP011271.1\|WP_082841641.1\|6477423_6478008_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052561937.1\|6483415_6484657_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|132847
NZ_CP011271.1\|WP_082841650.1\|6491203_6491455_+\|NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|236967
NZ_CP011271.1\|WP_082841640.1\|6476979_6477282_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372627
NZ_CP011271.1\|WP_082841648.1\|6488091_6489246_-\|deoxyhypusine-synthase	unknown	unknown	gnl\|CDD\|179117
NZ_CP011271.1\|WP_082841651.1\|6491830_6492217_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372298
NZ_CP011271.1\|WP_052561953.1\|6491430_6491664_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841656.1\|6497516_6498173_-\|NAD(P)H-hydrate-epimerase	unknown	unknown	gnl\|CDD\|223140
NZ_CP011271.1\|WP_082841654.1\|6496090_6496420_+\|tRNA-binding-protein	unknown	unknown	gnl\|CDD\|182232
NZ_CP011271.1\|WP_082841645.1\|6485136_6485541_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841647.1\|6487061_6488087_-\|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|379142
NZ_CP011271.1\|WP_162271858.1\|6495164_6496082_+\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NZ_CP011271.1\|WP_157469849.1\|6492400_6493564_-\|ISKra4-family-transposase	unknown	unknown	gnl\|CDD\|284250
NZ_CP011271.1\|WP_052561961.1\|6493988_6495155_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225689
NZ_CP011271.1\|WP_082841655.1\|6496439_6497459_-\|DNA-polymerase-III-subunit-delta	unknown	unknown	gnl\|CDD\|273455

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_162271857.1\|6481509_6482622_+\|hypothetical-protein	gnl\|CDD\|377450	pfam05076, SUFU, Suppressor of fused protein (SUFU). SUFU, encoding the human orthologue of Drosophila suppressor of fused, appears to have a conserved role in the repression of Hedgehog signaling. SUFU exerts its repressor role by physically interacting with GLI proteins in both the cytoplasm and the nucleus. SUFU has been found to be a tumor-suppressor gene that predisposes individuals to medulloblastoma by modulating the SHH signaling pathway. Genomic contextual analysis of bacterial SUFU versions revealed that they are immunity proteins against diverse nuclease toxins in polymorphic toxin systems.	5.2724e-29
NZ_CP011271.1\|WP_082841643.1\|6479146_6481384_+\|hypothetical-protein	gnl\|CDD\|223559	COG0483, SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism].	2.24012e-31
NZ_CP011271.1\|WP_082841642.1\|6478172_6478889_-\|arginyltransferase	gnl\|CDD\|234939	PRK01305, PRK01305, arginyl-tRNA-protein transferase; Provisional.	6.60426e-84
NZ_CP011271.1\|WP_052561951.1\|6490174_6491128_+\|HDOD-domain-containing-protein	gnl\|CDD\|370050	pfam08668, HDOD, HDOD domain.	7.76398e-40
NZ_CP011271.1\|WP_082841646.1\|6485687_6486878_+\|exo-alpha-sialidase	gnl\|CDD\|271234	cd15482, Sialidase_non-viral, Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.	4.94358e-103
NZ_CP011271.1\|WP_052561937.1\|6483415_6484657_-\|hypothetical-protein	gnl\|CDD\|132847	cd07208, Pat_hypo_Ecoli_yjju_like, Hypothetical patatin similar to yjju protein of Escherichia coli. Patatin-like phospholipase similar to yjju protein of Escherichia coli. This family predominantly consists of bacterial patatin glycoproteins, and some representatives from eukaryotes and archaea. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein, but it also has the enzymatic activity of a lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have also been found in vertebrates.	2.50012e-28
NZ_CP011271.1\|WP_082841650.1\|6491203_6491455_+\|NAD(P)-binding-protein	gnl\|CDD\|236967	PRK11749, PRK11749, dihydropyrimidine dehydrogenase subunit A; Provisional.	1.68935e-06
NZ_CP011271.1\|WP_082841640.1\|6476979_6477282_+\|hypothetical-protein	gnl\|CDD\|372627	pfam13532, 2OG-FeII_Oxy_2, 2OG-Fe(II) oxygenase superfamily.	6.9169e-05
NZ_CP011271.1\|WP_082841648.1\|6488091_6489246_-\|deoxyhypusine-synthase	gnl\|CDD\|179117	PRK00770, PRK00770, deoxyhypusine synthase.	0
NZ_CP011271.1\|WP_082841651.1\|6491830_6492217_+\|hypothetical-protein	gnl\|CDD\|372298	pfam12762, DDE_Tnp_IS1595, ISXO2-like transposase domain. This domain probably functions as an integrase that is found in a wide variety of transposases, including ISXO2.	7.66247e-09
NZ_CP011271.1\|WP_082841656.1\|6497516_6498173_-\|NAD(P)H-hydrate-epimerase	gnl\|CDD\|223140	COG0062, COG0062, Uncharacterized conserved protein [Function unknown].	6.37897e-61
NZ_CP011271.1\|WP_082841654.1\|6496090_6496420_+\|tRNA-binding-protein	gnl\|CDD\|182232	PRK10089, PRK10089, chaperone CsaA.	2.39145e-50
NZ_CP011271.1\|WP_082841647.1\|6487061_6488087_-\|trypsin-like-peptidase-domain-containing-protein	gnl\|CDD\|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	1.63044e-16
NZ_CP011271.1\|WP_162271858.1\|6495164_6496082_+\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	2.18569e-41
NZ_CP011271.1\|WP_157469849.1\|6492400_6493564_-\|ISKra4-family-transposase	gnl\|CDD\|284250	pfam06782, UPF0236, Uncharacterized protein family (UPF0236).	0.000203085
NZ_CP011271.1\|WP_052561961.1\|6493988_6495155_+\|hypothetical-protein	gnl\|CDD\|225689	COG3147, DedD, Uncharacterized protein conserved in bacteria [Function unknown].	0.00491521
NZ_CP011271.1\|WP_082841655.1\|6496439_6497459_-\|DNA-polymerase-III-subunit-delta	gnl\|CDD\|273455	TIGR01128, DNA_polymerase_III_subunit_delta, DNA polymerase III, delta subunit. DNA polymerase III delta (holA) and delta prime (holB) subunits are distinct proteins encoded by separate genes. The delta prime subunit (holB) exhibits sequence homology to the tau and gamma subunits (dnaX), but the delta subunit (holA) does not demonstrate this same homology with dnaX. The delta, delta prime, gamma, chi and psi subunits form the gamma complex subassembly of DNA polymerase III holoenzyme, which couples ATP to assemble the ring-shaped beta subunit around DNA forming a DNA sliding clamp. [DNA metabolism, DNA replication, recombination, and repair].	1.10578e-38

>NZ_CP011271.1|WP_082841648.1|6488091_6489246_-|deoxyhypusine-synthase
MHPHKPHYDRHAGTDANKAFLHKISRERIDPAGVAGGTSAADLIDGAFLSYNGGRLREGCQLYVRKMLANNGTIGLALSGALTPAGLGMSCLVPLVEAGFIDWIVSTGANLYHDTHYALGMDLYQAGPSLPDLELRENQVIRIYDIIFDYENLLGTDKFFRTLCRGEAFQQTMGTAEFHNLVGKYLAEREDQTGHRGKNLLAAAYRHGVPIFTSSPGDSSIGMNLAALMLEGSKLRIDPLRDVNQSAAIVWDAKASGGNSSVLILGGGSPKNFMLQTEPQIQEVLGLLEAGHDYFLQFTDARPDTGGLSGATPSEAMTWGKVDPDKLPDSVTCYVDSTIALPLLTAYALTRTEKRVPKRLFDKFPELTRRLEEGYAQTVAKREE
>NZ_CP011271.1|WP_082841647.1|6487061_6488087_-|trypsin-like-peptidase-domain-containing-protein
MRSRLFPRPTASRALLAAVLVAFASAAPAPAQQPRTEAPREPKYIDDDDVYKRLYDKLEELAKADKLLAHDKLVDRMKAGPAKIATTKSGDKVLAPEDVYKSAVRSVFIVGSVYPDKDGNWESGTYATAWVAAADGVLVTNWHVFEDLKPGEMFGVSDRDGNVYPLTDFLGGNKTADVAVFRIGAKGLTPLPIASGHADVGAWVGVISHPGDLFYLYTQGAITRYSTNTNEDGKTEKWMGITAEYASGSSGAPVLNKYGAVVGMAALTLSLDAGDDGKNPARRIRAMKMPKKGASRADDKKDDKLKDPAKPDPNPKGSTLQMVVKMVVPGPTVLKWLGKQE
>NZ_CP011271.1|WP_082841646.1|6485687_6486878_+|exo-alpha-sialidase
MTRFALVLVLAAFSVPAFAAEPEKIDLFDADRGGYKQYRIPGIVVTKSGVVLAYCEARKSARGDWGEIDILFRRSADGGKTWDEPKKIADVPGPKEKNPVALAQKLANKDDVTYNNPVMIADKSGAVHLLFCLEYMRCFYARSDDYGKTWTAPTEITASAFDPIKKGYDWKVLATGPGHGIQLKSGRLLCPVWLSLGTGGHAHRPSVVTTIFSDDAGKTWKAGEIAVPHTAEYVNPNESCVAELSDGTVVLNARSESKNNRRLVTHSADGATKWSKPVFDDALVEPVCVGSILVLPGKKPLLLFSNPDNLEKTGAKVPPAPGSGRDRKNLTVRLSEDNGKTWAAKRSVESGFSAYSDLAATKDGPVLLFYERAGEKGANYGRLTLARFGTEWIREK
>NZ_CP011271.1|WP_082841645.1|6485136_6485541_-|hypothetical-protein
MYRILALFALCVLPTGSFAQTVVVPVAPTLTGKWSGYWVSDKNGHTGPLHATFTPLGDDAYRVKYRGRFAKVIPFRYTTTMDVVGTGDGAVVLSAEKPLGPFGTFRTTATATNANFDATFTSRRDSGRFVLQRK
>NZ_CP011271.1|WP_052561937.1|6483415_6484657_-|hypothetical-protein
MVTLRHCAGSRTVFAGSLIALAVLVGCQTPRPAERARAKAHRVLASEDGPPIVPPGAVLASPADLIVGMRKPQHVLALSSGGLYGAYSAGVLDGWTRTGTRPEFDVVTGTSTGALIAPFAFLGSEYDAQAVKLYTGVRTSDIFHMRAWVTIPFRDALATSEPLQRLIESQITPALLDRIAEEHRKGRRLYVGTTDLRTRRAVIWDMGAIACRPRPEGGTLFRDVLLASASIPGVLPPVPFRIAVDGQRETEYHADGGVTAPLFMPPGVFELARLGPNTDPMQTRANFYAIVSGRLYPEEGPVRRRILPVLGASTGAMLFAHCRAELANTYWQSQLAGMRYHMIALRQDTEIQVDTAVSFDRKVMTQLYQEGLNDGQDGPSWMYIPPALSPCDGNYARGGLRLRTMPPMQPPAP
>NZ_CP011271.1|WP_162271857.1|6481509_6482622_+|hypothetical-protein
MSQLPFRDFYDAIKRNDIVKLQQILTDHPGFLQEDVGAESWLQIAAKYADIATVEFFVQVGLDVTPALEDAVLYDRVDVARLLLDHGAKILTTDVGWGGAPLLAVAIDSVKMTQLLLDRGADPNVSWGSPPTSVLSKALDRGRTEVAELLLAHGATPTAPAPESPVTLREEIVRHFALRIGPVEPLSIAEIVPGEVAVSVHIVPPAPGHGYLLLFTTGMSDRALTVPAGREDDRYAELVLLLPSDWKLNPDSLADSRSGWAIEWLRRAAHFFHEHRTWIGPGYGILANGSPPQPLAPGLPFDSLLLFHPESGTAQVRVADGREIRFYTVYPLHPDERFLETHQGPAALLERLAPQASFPIIDVHRPSAVG
>NZ_CP011271.1|WP_082841643.1|6479146_6481384_+|hypothetical-protein
MSFDPQLSVRAATLAYFADRAERFPGLVARIEEFFSAPTLETGRQVLRAYFRNHSTGDVESLRTITASFADKRVVRAIVASILADEEALAAIAARSYPHPIGFDKLVLDDDRATGFKFRLHVYWRGANFASLERLHLHRFEMASAIVTGELTNHVWRVVEFVPANELVRGMDLSPTIGEQAHTRRTMPAYAGYRRDANGDLRKTHLGTAVLERGASETFTSGDAYAQVLEDAHFVETNAETGFANGDFCSTVYIHGPSLVDGAGRSLPILFEETLLPDDNKLVPTIPAIPVETLRGCLNRYRDTLDEILKFYDWLYHPKHGRNLSVGMIAGYLLCEAFKTPHAIDAFERRYDECKDVLERSERAVRDLIEGRTNPAHLNDDDRNTRYVRLLLAKANSYPKGARIWAEDYGALTKEMWRYFGAIRGEMNSRITVLKPVWDGVVKRKLPGGMHYGHVGAMIEAAFEANGIAMKHFEAHWAGGGLVATHKDEHNIASVVDDEIEGRISEVLKGHFPSHRFYGEEHGDPNRALPAVGERRFLVDPLDGTRNFLCRREEFCIAIACQEWNGVGWVTTDGVVAHPASGRIFWAERGQGAFVIERTDLERRATVFVPAVDPANPLKHQLIDYSARGLDLAAQTDTFSELARSGAALRNSGSVALILAHMAGRGGTGAIITANDYDVEAGRLIAHEAGAWITQIVFVSGGDERTCTIVGAEERIHNALVVLVREQIQKHGGRLSDETLTPPGL
>NZ_CP011271.1|WP_082841642.1|6478172_6478889_-|arginyltransferase
MESLFVFTSPPSTCSYLPDQQWSLTYQMVSQLTPLEYQERLKAGWRRFGFSLFRPTCPACTACRSLRVPVATFKPDRSQRRCMAANDGDVKLVIGLPEVTDEKLDLYDRFHSYQHEHVGWSDHGPKDASDFAESFVDNPFVTQEWCYYLGEKLVGVGYVDNFPEGLSAIYFFHDPAERNRSLGTFNVLSIIRAAAQWNLPHVYLGYFVEGCRSLEYKARFRPNEALGVDGEWEAFREG
>NZ_CP011271.1|WP_082841641.1|6477423_6478008_+|hypothetical-protein
MKKLIALTGAGVGAAVGTVYAVEPVAVARFLDQAMKAVARAADGIEANPVPVSVALGTFLLTVVYHKARGKSFRESVEVAATRVQVVAVPTPVGEPENQVVKRAQARATRTQLIADQIALENQIRKLPADVKQAEKDVCYTEQAVTETEKSLTARRQAHTEAVEKLDVLRKELTVGRSELSAIAAELKKLAEVV
>NZ_CP011271.1|WP_082841640.1|6476979_6477282_+|hypothetical-protein
MWKLTMNFYQRVNGKVAGFPFHVDIPANGVVTMILNVQREVLFQIAKGDAVTDIPLPVGALLLLSGESRYVWKHRVLPADAPVSGGGHAIERVSLVLGFQ
>NZ_CP011271.1|WP_052561951.1|6490174_6491128_+|HDOD-domain-containing-protein
MFFKAFTRLFGRETPNVLAQPALIRDLGKVESFPTLSDTTVRALALANDQNATLANLAELVRRDGVLAVAVLKLANSAAFRGKRGTENVQQATVRLGMRRCQQIIAAVGVGGVFKYSTPQVGVMCEGLLRHALFTATLASRLNNAGGLGFRGEEFTAGLLHDIGRVIVCVRAPDAFMHADPMTFEEDSGILGRERDILQLDHCEIGVRFANANKLSPGVTSAILNHHFPKAERDHPVLVALTAAADGLANHVQRERKLANYQMEKCPGFLRLHECAGLETIRLIRKSLSKTVIESLRETRAMLQITAQKQPTRASKM
>NZ_CP011271.1|WP_082841650.1|6491203_6491455_+|NAD(P)-binding-protein
MSPGPFARRSPVARKFRVGIVGFGIAGATTAYLLARDGHSVTLLAHEASGVNRVFSGRRSGYPFWPCALLSWSVQGWTSRSGS
>NZ_CP011271.1|WP_052561953.1|6491430_6491664_+|hypothetical-protein
MDFPIRELMDIDACDQFLVGTLHPDGLHCPGCRRGDALSVHDRHRAPVFDYRCRHCGAVFNAYTGTALQKTHRSPVP
>NZ_CP011271.1|WP_082841651.1|6491830_6492217_+|hypothetical-protein
MKCSRTRGKKGICHPDPDDPPRRRANKQRGHGNFDNDRPPVVGVVGRGSGAVALAVVGRTDQETLTSFVGSSTVAEAMVYTDEWKGYARLAQNNRGHATVNHTPGQREWARDDDGDGIREVHDNTLEG
>NZ_CP011271.1|WP_157469849.1|6492400_6493564_-|ISKra4-family-transposase
MDCPHCSHRAPFHGYREKTVETLGGPVTCNRAYYYCGLCAKGSCPWDGRVGLTAGRLSPAVERLATLCGAVADSFEKGAELLKETTGVVLSASTVQRTTEATGERIAEHLQKGRTFGGKVAWDWFRDACGRTVGYIGIDATGVRQQGPRGEAADGRMAYVGMVFNPLPDRERVFECLPKPGVAMKARYISGLYPLAEMGPLIRRQGAQVDLDRAEVWVALTDGGAGLEDFVRLNFPRVEAVILDFYHAAEYLAQLARALHPTDEGAALAQTKSWSRLLRDEWGHVMIGVLEGWEWPSRKGLATVRSEVLGYFRNQVDRMDYPSYEAAGWYIGSGAVESACKTVVGQRMKGSGMRWSEPGSHAVCHVRALYRSERGQRTDFWRRSTTT
>NZ_CP011271.1|WP_052561961.1|6493988_6495155_+|hypothetical-protein
MSTIVAICPYCRSGGVRAKGTALGASAKCPKCKSSFTIVPDDDLPDWVAKASADAVVISAPSAEKPKLKLPAVEETRAMDALDVTEPSPVLPAEPRPQSRPAAQPAPVFTPDAGEPAAPTDAGFLLALGALTLVGPTVLASQLPFGRLIALALAAIGFIGGLLCLGAEGRARIGGALAALLHAGVAVVVLLLPSWLNLDPWDAPPVEEPQGPVVIEHGTGIRTMTTPGAVLDAGRSSWQLKDVRVTVRSVVGPVELRGPDNAKRTTKESYLQISVHIANVGFEREVSLSGWAAGLTTDGVRVTDGSGKQLDPAKFEGTFTPDRGRPAPRAMPGNVSEVRFLFPAPPKKTDSVQVQLSGVAFGYPEDIKFRISALGLQVRPPGSQDLPR
>NZ_CP011271.1|WP_162271858.1|6495164_6496082_+|DUF1559-domain-containing-protein
MFKRKAFTLIELLVVIAIISILIGMLLPAVQKAREAAARITCANNLKQIGLAMHMYHNNFERLPPSRVYGIHPIVPPPQADNLVYEGGATWAVFILPHLEEENFYREWRPNFTYYEQGTITRYNVKGYFCPSRRTSKDGFSVSGDVPQIAPANYPHQPGGLSDYAAVLDPSGSDSASQVSVQVNNAVNGPFRMETGFRFADFTDGLTNTLLIGEKQVAKGNHGVGWTDCSTYNGNYARCWSRSASRSNPLTTNPTDTGWKFGSRHSGVVQFCLADGSVRALPETTDPILLERLTTRNDGQVISEY
>NZ_CP011271.1|WP_082841654.1|6496090_6496420_+|tRNA-binding-protein
MEPLEAFGLVDVRMGRVLRAEPNAGARKPAFKLWIDFGPLGVKQSSAQLVALYTVEALVGRLVVAAVNLGTRKINGFNSEVLVLGAPDAEGNVVLLAPDHDVPLGGRMF
>NZ_CP011271.1|WP_082841655.1|6496439_6497459_-|DNA-polymerase-III-subunit-delta
MDALQFLAAKDSKRQSVYALVGDEDFLKRHARERIISVVLGEEDPSFAVSVYAGDKLDFSTARNELETLPFLAPCRVVIVENADKFVTDNRPALEAYFTKPSRVGVLILDVKTFPETTKLAKALPDAAKIGCKSLPIYKLSAWCVEWAKTAHKKKLVAGAADLLVELVGTSMGLLDQEIGKLANAVGSKPGISAEDVDALVGRSKAADVFRIMDAVGEGRPGEALSILQELFGEGEDPMAVIGPLTAQLRKLATVGRLHLVEKMALGPAMDAANVPKWDKARISFDKQLKHLGGRRLLKLPDWLVEINHGLKGGNALPERVQVERLVVTLARPLALAKA
>NZ_CP011271.1|WP_082841656.1|6497516_6498173_-|NAD(P)H-hydrate-epimerase
MFTLSRDEVRELDRRAINEFGVPGVVLMENAGRGCAELLMRLNLERKPVVILCGPGNNGGDGFVIARHLDNHGWPVKAWLLADAKKLTGDAAVNYGAAKASGLVGDQVSALDGWVVDALFGTGLSRALAAPYDGVVAQINASRCPVLAIDIPSGLDCDTGEPLGPTVKATHTATFVAHKRGFLNTASKPWTGEVHVIDIGAPRVLVDEYKQKTGERPA

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Crispr_ID: NZ_CP011271_20

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_20

6621299-6621387

Orphan

Consensus_repeat	Method
CTACGAACGCCGGCCCCTCCGGGGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_20

>merge|NZ_CP011271|20|6621299-6621387|CRISPRCasFinder
CTACGAACGCCGGCCCCTCCGGGGCGGAAACGCGCTGACGGTTTTTGTCTTCGTTTTGGTTCACTACGAACGCCGGCCCTCCGGGGCGA

>NZ_CP011271|20|20|6621299-6621387|CRISPRCasFinder
CTACGAACGCCGGCCCCTCCGGGGCG	GAAACGCGCTGACGGTTTTTGTCTTCGTTTTGGTTCA
CTACGAACGCCGGCCCTCCGGGGCGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_052555759.1\|6606732_6607788_-\|magnesium/cobalt-transporter-CorA	unknown	unknown	gnl\|CDD\|213356
NZ_CP011271.1\|WP_052555758.1\|6606156_6606627_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367156
NZ_CP011271.1\|WP_082841724.1\|6628846_6629956_-\|mandelate-racemase	unknown	unknown	gnl\|CDD\|227284
NZ_CP011271.1\|WP_162271863.1\|6605011_6605878_-\|peptidase-M50	unknown	unknown	gnl\|CDD\|100085
NZ_CP011271.1\|WP_157469072.1\|6623936_6624863_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841720.1\|6614111_6615158_-\|KpsF/GutQ-family-sugar-phosphate-isomerase	unknown	unknown	gnl\|CDD\|182814
NZ_CP011271.1\|WP_082841721.1\|6621569_6622877_-\|PQQ-binding-like-beta-propeller-repeat-protein	unknown	unknown	gnl\|CDD\|379140
NZ_CP011271.1\|WP_082843204.1\|6630641_6631343_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841719.1\|6609800_6613559_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236090
NZ_CP011271.1\|WP_082841716.1\|6608022_6608616_+\|RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|224511
NZ_CP011271.1\|WP_082841718.1\|6609203_6609644_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052555777.1\|6623191_6623785_-\|glycine-zipper-family-protein	unknown	unknown	gnl\|CDD\|379218
NZ_CP011271.1\|WP_082841717.1\|6608612_6609200_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082843427.1\|6616236_6621258_+\|transporter	unknown	unknown	gnl\|CDD\|185219
NZ_CP011271.1\|WP_052555787.1\|6631468_6632926_-\|DUF1501-domain-containing-protein	unknown	unknown	gnl\|CDD\|369346
NZ_CP011271.1\|WP_082841723.1\|6626512_6627649_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|130253
NZ_CP011271.1\|WP_052551189.1\|6624997_6625288_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052555778.1\|6625620_6626475_+\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|224155
NZ_CP011271.1\|WP_052555783.1\|6627768_6628773_+\|WD40-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|238121
NZ_CP011271.1\|WP_052557391.1\|6613573_6614107_-\|HAD-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|224692

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_052555759.1\|6606732_6607788_-\|magnesium/cobalt-transporter-CorA	gnl\|CDD\|213356	cd12822, TmCorA-like, Thermotoga maritima CorA-like family. This family belongs to the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes. Members of the Thermotoga maritima CorA_like family are found in all three kingdoms of life. It is a functionally diverse family, in addition to the CorA Co2+ transporter from the hyperthermophilic Thermotoga maritima, it includes three Saccharomyces cerevisiae members: two plasma membrane proteins, the Mg2+ transporter Alr1p/Swc3p and the putative Mg2+ transporter, Alr2p, and the vacuole membrane protein Mnr2p, a putative Mg2+ transporter. Thermotoga maritima CorA forms funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport by Alr1p. Natural variants in this signature sequence may be associated with the transport of different divalent cations. The functional diversity of the MIT superfamily may also be due to minor structural differences regulating gating, substrate selection, and transport.	9.65608e-96
NZ_CP011271.1\|WP_052555758.1\|6606156_6606627_-\|hypothetical-protein	gnl\|CDD\|367156	pfam02724, CDC45, CDC45-like protein. CDC45 is an essential gene required for initiation of DNA replication in S. cerevisiae, forming a complex with MCM5/CDC46. homologs of CDC45 have been identified in human, mouse and smut fungus, among others.	1.17394e-11
NZ_CP011271.1\|WP_082841724.1\|6628846_6629956_-\|mandelate-racemase	gnl\|CDD\|227284	COG4948, COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only].	4.47431e-58
NZ_CP011271.1\|WP_162271863.1\|6605011_6605878_-\|peptidase-M50	gnl\|CDD\|100085	cd06164, S2P-M50_SpoIVFB_CBS, SpoIVFB Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50B), regulates intramembrane proteolysis (RIP), and is involved in the pro-sigmaK pathway of bacterial spore formation. In this subgroup, SpoIVFB (sporulation protein, stage IV cell wall formation, F locus, promoter-distal B) contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain. SpoIVFB is one of 4 proteins involved in endospore formation; the others are SpoIVFA (sporulation protein, stage IV cell wall formation, F locus, promoter-proximal A), BofA (bypass-of-forespore A), and SpoIVB (sporulation protein, stage IV cell wall formation, B locus). SpoIVFB is negatively regulated by SpoIVFA and BofA and activated by SpoIVB. It is thought that SpoIVFB, SpoIVFA, and BofA are located in the mother-cell membrane that surrounds the forespore and that SpoIVB is secreted from the forespore into the space between the two where it activates SpoIVFB. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown.	5.59782e-56
NZ_CP011271.1\|WP_082841720.1\|6614111_6615158_-\|KpsF/GutQ-family-sugar-phosphate-isomerase	gnl\|CDD\|182814	PRK10892, PRK10892, arabinose-5-phosphate isomerase KdsD.	3.18632e-71
NZ_CP011271.1\|WP_082841721.1\|6621569_6622877_-\|PQQ-binding-like-beta-propeller-repeat-protein	gnl\|CDD\|379140	pfam13360, PQQ_2, PQQ-like domain. This domain contains several repeats of the PQQ repeat.	1.7129e-18
NZ_CP011271.1\|WP_082841719.1\|6609800_6613559_-\|hypothetical-protein	gnl\|CDD\|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0.000319187
NZ_CP011271.1\|WP_082841716.1\|6608022_6608616_+\|RNA-polymerase-sigma-factor	gnl\|CDD\|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	1.38878e-40
NZ_CP011271.1\|WP_052555777.1\|6623191_6623785_-\|glycine-zipper-family-protein	gnl\|CDD\|379218	pfam13488, Gly-zipper_Omp, Glycine zipper.	0.000100493
NZ_CP011271.1\|WP_082841723.1\|6626512_6627649_+\|ABC-transporter-permease	gnl\|CDD\|130253	TIGR01185, membrane_spanning_subunit, DevC protein. This model describes a predicted membrane subunit, DevC, of an ABC transporter known so far from two species of cyanobacteria. Some experimental data from mutational analysis suggest that this protein along with DevA and DevB encoded in the same operon may be involved in the transport/export of glycolipids. [Transport and binding proteins, Other].	1.61643e-11
NZ_CP011271.1\|WP_082843427.1\|6616236_6621258_+\|transporter	gnl\|CDD\|185219	PRK15319, PRK15319, fibronectin-binding autotransporter adhesin ShdA.	4.35861e-21
NZ_CP011271.1\|WP_052555787.1\|6631468_6632926_-\|DUF1501-domain-containing-protein	gnl\|CDD\|369346	pfam07394, DUF1501, Protein of unknown function (DUF1501). This family contains a number of hypothetical bacterial proteins of unknown function approximately 400 residues long.	1.15548e-138
NZ_CP011271.1\|WP_052555778.1\|6625620_6626475_+\|metal-dependent-hydrolase	gnl\|CDD\|224155	COG1234, ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only].	7.96077e-12
NZ_CP011271.1\|WP_052555783.1\|6627768_6628773_+\|WD40-repeat-domain-containing-protein	gnl\|CDD\|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	5.21297e-70
NZ_CP011271.1\|WP_052557391.1\|6613573_6614107_-\|HAD-hydrolase-family-protein	gnl\|CDD\|224692	COG1778, COG1778, Low specificity phosphatase (HAD superfamily) [General function prediction only].	1.10655e-67

>NZ_CP011271.1|WP_082843427.1|6616236_6621258_+|transporter
MTVISTLLRRLQKARSFRPGCPLPARTRLHVTLLEDRTVPTTLTWIGGAMGNNDWSTSGNWSDGAANTEVPDSADDVLVFDGTASTFTSNNDISSLTVSDIQLSFSGYTITGSQPVTVNTAVTDTTTAGSNTISLSIDGTAVLTKSGGSSLFLSGTNTFTGATTVSGGVLELDGGAAVADTSAVTVAAGTTLNLDANETIGSLAGAGNVTLSTFTLTAGGDNTSTTFSGVASGTGGLTKAGTGTLTLTGTNTYTGATTVSAGTLTLNGGTALDDTSAVTVAAGATLDLGASETIGSLAGAGDVTLGANTLTAGGDNSSTTFSGVASGTGGLTKAGTGTLTLSGANTYTGATTVSAGTLALSGNAAIADAAAVTVSTGATLALNNDETIGSLAGAGDVTLGANTLTAGGDNSSTTFSGVASGTGGLTKAGTGTLTLSGANTYTGATTVSAGTLTLNGGTALANTSAVTVSTGATLNLGASETIGSLAGAGNVTLSTFTLTAGGDGTSTTFSGVASGTGGLTKAGNGTLTLSGANTYTGATTATAGSLALNGGSALADTSALTVDAAAVLFLGASETIGSLAGAGSLSIGAFTLTTGGDNTSTTFSGGIGGSGGVTKTGTGTFTLSGTTNNFSGATTVSAGTLALSGGSALDDTSAVTVAAGATLDVGANETIGSLAGAGNVTLGANTLTAGGDNSSTTFSGTAAGTGGLTKAGSGTLTLSGANTYTGTTTVSAGTLTLAGNSAIADTAAVTVSGGATLALGADEIIGSLAGAGNVTLGVNFLTAGGDNTSTTFSGVIGGTGTLTKAGSGTLTLSGANTYTGTTTVATGTLALSGGTALANTSAVTVSAGATLDVGANETIGSLAGAGNVTLGASILTAGGDNSSTTFSGIAAGTGGIAKEGTGALTLSGTNTFSVTAVSAGTLTLNGGSALADTSFVTVSPGATLDLGASETIGSLAGPGNVTLGANTLTAGGNNSSTTFSGVASGTGGLTKAGTGMFTLAGANTYTGATTVSAGALTLNGGTALADTSAVTVSAGAALDLGAAETIGSLAGAGGVTLGANTLTAGGDNSSTTFSGDISGTGGIAKAGTGVLTLSGTNSYTGTTTVSAGTLLVTGSIATSSDVQVTGGTLGGTGTVPAVTVNTGGTIAPGTSPGTLNTGALTLTTGGTFSAEVNGTTPGTNYDQAVVTGAVDVTGSTLTVTLGFTPVAGTSFILIDNDLVDAVTGTFNGLAEGATFTSGGVTFTISYVGGDGNDVVITTAPPTVSINNVTAAEGNTGGTSFTFTVTLSNPSSQTVTVDYATAAGTATAGTDFTAASGTLTFAPGETSKTVTVTVTGDTEIESDETFTVVLSNPTNTTIATGTGTGTITNDDAATSTTVISVGAGNGTPGTVVPVDPATGQQGTPILAFAGFGGEIRVASGDINGDGQADTITGAGAGATGGHVKVFSADGTLLRSFLAFDGFSGGVFVTSGDVNGDGFDDIIVSADAGATPHVKVFSGANGALLQSFFAYDIGFRGGVRVSVGDVNGDGFDDIVTGTGAGTTAHVKAFSGKDGALLRSFLAYDAGFSGGVYVAAGDLNGDGLDDIVTGSGPGAPGGHVKVFNGSDTSLIQSFLAYDAGFRGGVRVGVGTVNGSAAVLTGAGPGAGPHVKAFVNGVLVASLLAGDPTFSGGVYVG
>NZ_CP011271.1|WP_082841720.1|6614111_6615158_-|KpsF/GutQ-family-sugar-phosphate-isomerase
MNDSTGTAFDKLDYARRVLRTEAAALDVVAGRLDDGFGRVADELFACRGRVAVVGVGKSADVGQKIVGTFNSTGTRAYTLDATRAVHGDLGSVHPDDVALLLSHSGESEELIRLLGPLKKLASSLVAITSSAGSTLGRAAVAAVVYGPIKEACPLALAPSSSTTVMLALGDALAFTLLEQRQFTADEFAKFHPAGSLGRKLAVVSECMRCGAELRIAVQTDTVREVFAKVRHTGRRTGAIMLVDADGRLAGLFTDSDLARLFENREDRLLDSPIANVMTHAPVVIGPHARVSVALDVLKARKFSELPVVDEGGKPVGMLDITDLIGLDPLAGGAETRLTPRVVARKSA
>NZ_CP011271.1|WP_052557391.1|6613573_6614107_-|HAD-hydrolase-family-protein
MQTSDIPARAAAIELLLLDVDGVLTDGRVVYADDGRELKFFHVRDGSGLKLWRAAGKRAAIVSGRDSRAVERRAAELGIAPVLQGRDDKLRAFDDVLALTGASPEQVCAIGDDLPDVPVLRRCGLAVAVADACPEARAVAHYVTAVPGGHGAVRDLIEWLLKVQGRWAELTTGYTNT
>NZ_CP011271.1|WP_082841719.1|6609800_6613559_-|hypothetical-protein
MLTPRRTMLLLAGFVLFAGAYAVYAQLLGWLDGLPQLPPQMLAVRPLGEFVPPESSTVLKTELKLIEAFGANSPETNGAHYKMQFDFKSGDSSVVVASGMPPDKPNSTRVTLTPFSIAVFSKPKPPHLRQPGEVTEISTAHADKGVLEFDRVINNLADMKKAALLKVELISDFELALPDPRRGVVHITNNQRTNDPNRFLVLRTVGPVFYRNPKTAGANATAPDFWTDAPVEIVDRQNLPRSVGSPAPVTAPTKSEDNRNTGAIAAILSGQRLPPPTLTAVGLRVYLEPDPPPNQPKKEPKPGTTPVKGVRRIEFQEQVVLNLWVNNGESLAGTTPVQSNVPKSSGLAFVPPPAAIAGITGGLGTAAYNTRLMDRALLQIDTRGPFAYDAEKSLARFDVVPQTDSNLPNDVQVTKIPSRGGTSSLFSQVLELEFNGGPTGASRAANTPAIKRLHAWVNAPGRFVTVASQEETAPPTPGAAPGLSSTQAYGRDLVHEQAASKTILNGTPVVVVRDNNTLKAGTPQEPATLTIEPGPPIAQAQGQPPVRKLQMTVRGAGEVALTDAANNNQPLRAEWRISLVQSKEVISGREQDRFDFTGDAKLEDRKADYWLKGNVIKLWFQPRVEPPADEKASTDTKIAAGGSPPADGKANADTKVASGGGQPKPSRVEAIGKVTSHSTDYDIKESDQLTVHFIDANPVPTVGAVAQSNKPASPDAVASGPPSPPTAPGAAPKLPDPMPPAGPEAPKLPEPIAKAPEKPKPPFEISAKTIETFVKRIPVAPADKQAGGKPADEKPAEPPAAKYQLDRARCEDNVVVHQEPTDPSKQRGVDIFGRLLLIEGTNDGSVMTVFGWPDKIGEVHQEEMSLLGPKIVLNQVLNSASVDGRGSLTMPTKNNFAGSELAQAEVVIVHWRDSMTFNGAQRSAVFTGKVRAHQGESAVECHRMDVVFDRPVYFNQARKKPAPPPGVDPKDPMTGAAAKKDESAKIDRIRCHRAPADEDDSKVESGVLYTQVDYDKDGKLLKAQWLRASELTMEAQAQESSGGEKFPRVTAEGPDGRLRIWQRGEANPAGPPVGAKPAKDEQEMKLTFIKFTGRMIGVDKAKLYQAATFSGEVTAIHVPTNSPTLEVDGLEYNLPPRAVLLTCNDKLLVWSQKAQGDTPAAQNMKASGNAFLRSDDYEGTAATIESRGNAVTLTGSEAAAARFSNRFRGGNEQIGKVITYDRSTGASSIKEGAGTSIGAPPKNRPATPAPKK
>NZ_CP011271.1|WP_082841718.1|6609203_6609644_+|hypothetical-protein
MSALVLVAYMFVACPTEDPVRVTVVIVLATADNTTVDPKLKELAKEVQKRDPKLTGFKLVATECKSIPVGGNTTISLTDKQELKMKVDQSKDEKGRISLTLNPPGMDAVTYACACDKFFPVVTPHRTKGGEQLIIAIMAKPCTAKK
>NZ_CP011271.1|WP_082841717.1|6608612_6609200_+|hypothetical-protein
MTPAPQQPEPNERDVLSAYAEGIRSAARAVRPDEPSEPEWDAVYRNIRARLHPAAPVPPPRRGHWRTTVLVAAGAAVTAVAAAIAWVALTPTPTEKREIVGVRPPLPSVVALAPAPREVTDPLADYTVLPMATAEEVDFHRVPGSGWFPVGTDPLPSVISLATTDEVELDAPHPSWPRVTLSPGDAPVLFVAKPR
>NZ_CP011271.1|WP_082841716.1|6608022_6608616_+|RNA-polymerase-sigma-factor
MPIAALPTPPALLTDDALLARFATGDRTALDDLFRRYRGIAYRVAYRLLGREADALDAVQDGFVNALTHLDRFGGRSSFKTWLLRVVCNAALDIGRQRKRNERVPQVPRGFSPDGFGADDLPPAETNLVRSDLRRVIDAALARLPDVQRQTFVLHVEGELTYREVADALGISIGTVMSRLFYARQKLKDLLAAYQQP
>NZ_CP011271.1|WP_052555759.1|6606732_6607788_-|magnesium/cobalt-transporter-CorA
MITVHRWNGSCCERTGAEGLPESAATIPAEEFIWVDMSNPTPEEEARVFQKFFAVHMLTLEDITRMRREPDQGAHFPKVEEFPDYLFVIVNPLPPGLSKLAASKGKVPEGEAKLPSASRMLRRHRPQLSAVLTKNVLITHSMESVPCIASAHQFLARHGDSARRGPDYVFHIVLDAMVDEYAPVVEWVAGKLDRLESRIFTRPTAKLISGILKLKRIVTGMRKTLIIEREVLSRLIRGEFELVEAREIAYYRNVYDHLVRYTELIEAAREMVSDLGETHLAAVSNRLNQIMKVLTMISTTILPLTLISSVYGMNFKHMPELEWEWGYPLALGLMLLTGIASLAFFRWKKWI
>NZ_CP011271.1|WP_052555758.1|6606156_6606627_-|hypothetical-protein
MAKGRKSRMDLRREAEALEAKQREEETEGEETEDEDEEEEDSDTEGDAEAEGEGDAEGDADAEGDGDSGDDDGDDEDRPKKKKKVKKVAVKKTTTKRSRTAKEVRTRAVWIVFDNGSKVVEKFPYNQKEEAEALLAKKLEEKKTFYLNLVKEEIKE
>NZ_CP011271.1|WP_162271863.1|6605011_6605878_-|peptidase-M50
MFSSLKLGRLFGIDLYIHPTFWLLPLFVVMSGAGASAGELTSEVLFVFAVFACVALHEFGHALAAASYGIRTRDITLYPVGGVASLEGMPEKPGQEIVVALAGPAVNVVIAVGLLLGLSAGGLALPWERMSDPIEAFVNRLLVANVFLVVFNLLPAFPMDGGRVLRALLATQMTRLRATEVAVTVGTVVAVLFFVGGFMIPQFSLMAIAVIVWLMGQSELASLRMLAARREMGRRARAFFGEPEPAPEYPRDTNVDLAARRFTGIAWDTVHGVWIQWVNGVPVRALSR
>NZ_CP011271.1|WP_082841721.1|6621569_6622877_-|PQQ-binding-like-beta-propeller-repeat-protein
MALRVPFLVCTFLFTVTPAVVTAADWPGFRGPNRDGICTETGLLKKWPTGGPKQVWTAKNLGLGWGTPSVADGKIFGIGTRDGKDGVWALKEADGTELWFTPFADPAKGLAPQTNGPASTPTYHNGKLFVVSANGTLSCLDAAKGTLVWKKNYVDDFGGKIPTWAYTDSVLVDGDKVICAPSGSKGAVAALKFENGDVVWKTEVNPVGGGFGYSSPLKATIDNVPMYIVLLGQSSGVVGVHAETGKLLWQYKNAPAAGGVAQIPIPIVKGDKVWVSCAYNGGAALLQIVPKGAGAFEAKELKAYKKPELNNHHGGMVLVGDYIYFGHDQNNGKPVCVELKTGEIKWGPEKLPAGGQGSAAVLFADGRLYFRYQNGVMVLIEPSPEELKVVSSFKLPEANVKTHSQSWPHPVIANGKLYIRDQNVMYCYDVKEKTN
>NZ_CP011271.1|WP_052555777.1|6623191_6623785_-|glycine-zipper-family-protein
MFAFAAAGAGCASMNNTEKGAIGGGVVGTALGTAVGAATGHTGAGAVIGGLAGTATGALVGNDIDKQERRDRDINQAAALAAAQQQQQRMGMFDVIRLAQGGHDDTVIINQIRTTGSTFQLTASDLDELKRAGVSSRVIAEMQAARPAPTRVIVRDAPSVVYDSGPVYVRPAPVVVVGPPRPYSYGYGYGYYRRGGW
>NZ_CP011271.1|WP_157469072.1|6623936_6624863_-|hypothetical-protein
MAADVSFAKTREHLRELLGVKLAPETARQLVGTHGRAMTTFQPQDHATAQTFRQTPGEIELAIDAGKVNTREEGWKDLKIAVISKREAGTAVSPEQWQDDERLPPAGAVVSFAMIAKSKVFRRRWGPSLRQLGVAQWSSVHALGDGASWIWKSVNRVLPGCRETLDIYHASERLSLCAQRIFGQGTDEARAAFERGRDVLLREGWGGVCVWVSELLSVETLEERTRRQKATEKLLGYFAKHTNRLAYRDRLARGQAIGSGAVEGQAKTLGLRLKARGARWLKKNVRPMASLVCVRNSIQWQAYWSLAA
>NZ_CP011271.1|WP_052551189.1|6624997_6625288_-|hypothetical-protein
MSKTVTIEIPAESEALVRQLLAVHEELQALALSAANGTVLDACETAVIPKGRELTKNLLADAVTRRIQAAEKKGRRSESATAGEPKKTAGKSPGSS
>NZ_CP011271.1|WP_052555778.1|6625620_6626475_+|metal-dependent-hydrolase
MLPDRPVDNAPYYSLSHGGLTVEGWSRAAVQSYWRIPELKIGFDLGAQPWDFMGTPTWFVSHTHLDHVAALPVYVARRRMMKMEPPTVYVPTEGLEDVKKLMMIMHRLDRGRQLAHLKGLTAGDEIELSREHLVTVFNTTHTIPSRGFVVWERRNKLKDEFVGLPGDKIRDLKLSGTPITREVRIPIVAYTGDTSPAGLDACPACFEAKILITEMSFIRASHRRDKIHKFGHMHLDDFVERAPRFKNELIIAAHFSTRYHPNEVRKLLDNKLPADLKAKMHLWV
>NZ_CP011271.1|WP_082841723.1|6626512_6627649_+|ABC-transporter-permease
MSYSLTTIWYERQRFLPAILAVAFSAVLVAVQSGLVLGLLSMMSLPVDRATSDVWVGYPAVRSVDTGRPVPERWVSRLAAQPEVERAEGAIIGFTPWTRNGEIPAKTTTEVCTVVGTRLDANSLAAMEVVRNNRELLASLTQPLSIAVDESELGRLGIRGAGDTAEILGVRVRVVGLVTGCRSLGGPYLFCSLETARVLLHYQQDEVTYLVAKCTKPEDAPAVARRMNGYAQLSAFTADEFSARSRLHWLTTTKAGVAIGFTALLGLLVGAVVTSQTLFAATAASQREFATLRAMGIPKWRLKFSVLAQSFWVGLFGIALAAPITIALAEGATAMGTAVRLHPFILGGAAAVTMCMAVGSGLAALRSFQKVDPAHNIR
>NZ_CP011271.1|WP_052555783.1|6627768_6628773_+|WD40-repeat-domain-containing-protein
MVRTKRAVALVLVGLLTGVAAARRPADDLSPRCELEGHTEQILALAFSPDGTRLASAADDGRVKVWDVTTDRVVWTGARVQGSVWCLAFSPDGKLLAAEWGAGRVQLWATTTWRRVDVCRDRQGWIKGLAFSPDGKLLASAQGAGRIALWDTATYERVATLDGHDPKEDVAAVAFSPDGKLLASAGGDKCVRLWDVAKCETTAIFEGHTHWVRTVAFSPDGKIVASGSNDETIRLWSTVTHQPVRAMTAGGVIMSVAFSPDGTRLVAAGGGDRIRVWDTGTGKCVATAVHGDMSKVQSPLEKEMYITAVAFRPNGRTIASGGRNRVIKLWNWNR
>NZ_CP011271.1|WP_082841724.1|6628846_6629956_-|mandelate-racemase
MRITRISAWQVDLPLHEGSYKWSGGKSVTVFDSTVVAVETDAGVTGYGEVCPLGPAYLPAYAAGVRAGLQELAPKLLGEDPTQLGKLNRTMDAALKGHPYVKSAVDVACWDILGKVSGLPVCVLLGGRYGEDFHLYRAISQESPEAMAANVAGYRAEGYRRFQLKVGGDPDTDIARIKAVAAVLQPGDRLVADANTGWLQHEAVRVVRAVRDIDVYIEQPCLTYEECLAVRRNTDHPFVLDEVVDGIDMLVRGHAEGAMDVVNLKISKLGGLTKTKQLRDLCISLGIGMTLEDSWGGDIVTAAIAHLAHSTPTEFLFSSTDFNSYVTRSIATGAPQRQNGRLAAPVVPGLGITPKLGEFGAPAVDARNG
>NZ_CP011271.1|WP_082843204.1|6630641_6631343_+|hypothetical-protein
MSVAKGTKPHQQVSILLDQVAARGLQVRGVVLDAGFDSGETLLLLQQRDLYYAVPIRKKGKGTNRRNECDAQPSGTIATMGWVTEKSRRAVSTRVLVWRRPGESHARVYAFSGWGKGTAVSEATRAWLGRRRYRERFGIETSYRQKNQARGWTTSTNPEYRLLLEGVALVLRQVWVCLALQIARARKRNPSAWVRELPLVEMLDWLTLRIRSRYPRTRCITLTHNTLTRTATP
>NZ_CP011271.1|WP_052555787.1|6631468_6632926_-|DUF1501-domain-containing-protein
MLSRRDFLFHSGGGLGGIALASLLGADRLSADAPARADGGLHHKPKAKRVVQLFMAGGASHVDLFDFKPELVKHHGKEANFGEHVEAFQNGLGPWLKPVWDFKPYGKCAKPLSEVVAPLGDVVDEMAFVHNMVGKTGVHSQGTLLQTTGFNRPGFPGMGCWASYGLGSMNQNLPTFVVLPDHRGLASNGTKNWDSAFLPAQHQGAAIYPGTKTPIEDLFPDDRAKFITRASDKAGIDLLAQLNHVHADTRAGDERLGARIKSYELAAKMQLAAPEALDISKETARTLKLYGLDHGKGTFDKDINPIEETDYFGRKCLVARRLLERGVRFVQIWSGNDNGFPRRNWDSHEDVKRDHGPLAYGMARGAATLIADLKRLGLLEDTIVLWTTEFGRMPSSQGGKGRDHNPYCFTSWLAGGGVKGGVSHGPSDDFGYKPADRKNPTEVYDIHATILHLLGIDHTKLTVRHNGIDRRLTDVHGHVINELIG

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Crispr_ID: NZ_CP011271_21

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_21

6667878-6667988

Orphan

Consensus_repeat	Method
CGGGACCAAGATCCACGGCCGCGTGAATGCGGCTCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_21

>merge|NZ_CP011271|21|6667878-6667988|CRISPRCasFinder
CGGGACCAAGATCCACGGCCGCGTGAATGCGGCTCGAACTGCTTTTCGGTGGGTACCGGTAGCGGGTCGATTACACGGGACCAAGATCCACGGCCGCGTGAATGCGGCTCG

>NZ_CP011271|21|21|6667878-6667988|CRISPRCasFinder
CGGGACCAAGATCCACGGCCGCGTGAATGCGGCTCG	AACTGCTTTTCGGTGGGTACCGGTAGCGGGTCGATTACA
CGGGACCAAGATCCACGGCCGCGTGAATGCGGCTCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_082841752.1\|6672682_6674215_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NZ_CP011271.1\|WP_082841755.1\|6678469_6679447_-\|transporter	unknown	unknown	gnl\|CDD\|379259
NZ_CP011271.1\|WP_082841739.1\|6657818_6658061_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841746.1\|6665334_6666003_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378467
NZ_CP011271.1\|WP_157469875.1\|6676616_6677855_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377970
NZ_CP011271.1\|WP_157469873.1\|6674404_6675016_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052557395.1\|6675311_6675743_+\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
NZ_CP011271.1\|WP_082841740.1\|6658081_6658780_-\|Uma2-family-endonuclease	unknown	unknown	gnl\|CDD\|368559
NZ_CP011271.1\|WP_082841741.1\|6658838_6660113_-\|glutamyl-tRNA-reductase	unknown	unknown	gnl\|CDD\|234592
NZ_CP011271.1\|WP_052555839.1\|6668482_6668719_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841743.1\|6661180_6662392_-\|GTP-binding-protein	unknown	unknown	gnl\|CDD\|223597
NZ_CP011271.1\|WP_052555834.1\|6666054_6666261_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052555844.1\|6675826_6676459_+\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|376328
NZ_CP011271.1\|WP_082841744.1\|6662503_6663721_-\|DUF1501-domain-containing-protein	unknown	unknown	gnl\|CDD\|226587
NZ_CP011271.1\|WP_082841747.1\|6666273_6667254_-\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NZ_CP011271.1\|WP_082841757.1\|6681942_6684255_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|185008
NZ_CP011271.1\|WP_082841756.1\|6679683_6681660_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|185001
NZ_CP011271.1\|WP_082841745.1\|6663732_6665301_-\|DUF1800-domain-containing-protein	unknown	unknown	gnl\|CDD\|378055
NZ_CP011271.1\|WP_082841751.1\|6668827_6672460_-\|c-type-cytochrome	unknown	unknown	gnl\|CDD\|274225
NZ_CP011271.1\|WP_082841742.1\|6660109_6660946_-\|cytochrome-c-biogenesis-protein-CcsA	unknown	unknown	gnl\|CDD\|307628

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_082841752.1\|6672682_6674215_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.51928e-97
NZ_CP011271.1\|WP_082841756.1\|6679683_6681660_+\|HAMP-domain-containing-protein	gnl\|CDD\|185001	PRK15041, PRK15041, methyl-accepting chemotaxis protein.	1.8276e-89
NZ_CP011271.1\|WP_082841755.1\|6678469_6679447_-\|transporter	gnl\|CDD\|379259	pfam13557, Phenol_MetA_deg, Putative MetA-pathway of phenol degradation.	1.0889e-16
NZ_CP011271.1\|WP_157469875.1\|6676616_6677855_-\|hypothetical-protein	gnl\|CDD\|377970	pfam08305, NPCBM, NPCBM/NEW2 domain. This novel putative carbohydrate binding module (NPCBM) domain is found at the N-terminus of glycosyl hydrolase family 98 proteins. This domain has also been called the NEW2 domain (Naumoff DG. Phylogenetic analysis of alpha-galactosidases of the GH27 family. Molecular Biology (Engl Transl). (2004)38:388-399.).	3.6432e-30
NZ_CP011271.1\|WP_052557395.1\|6675311_6675743_+\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	3.18865e-85
NZ_CP011271.1\|WP_082841740.1\|6658081_6658780_-\|Uma2-family-endonuclease	gnl\|CDD\|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	4.82351e-20
NZ_CP011271.1\|WP_082841741.1\|6658838_6660113_-\|glutamyl-tRNA-reductase	gnl\|CDD\|234592	PRK00045, hemA, glutamyl-tRNA reductase; Reviewed.	9.75758e-146
NZ_CP011271.1\|WP_082841743.1\|6661180_6662392_-\|GTP-binding-protein	gnl\|CDD\|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	1.12235e-121
NZ_CP011271.1\|WP_082841746.1\|6665334_6666003_-\|hypothetical-protein	gnl\|CDD\|378467	pfam10670, DUF4198, Domain of unknown function (DUF4198). This family was previously missannotated in Pfam as NikM.	0.000917534
NZ_CP011271.1\|WP_052555844.1\|6675826_6676459_+\|30S-ribosomal-protein-S9	gnl\|CDD\|376328	pfam00380, Ribosomal_S9, Ribosomal protein S9/S16. This family includes small ribosomal subunit S9 from prokaryotes and S16 from eukaryotes.	1.59765e-32
NZ_CP011271.1\|WP_082841744.1\|6662503_6663721_-\|DUF1501-domain-containing-protein	gnl\|CDD\|226587	COG4102, COG4102, Uncharacterized protein conserved in bacteria [Function unknown].	1.46998e-55
NZ_CP011271.1\|WP_082841747.1\|6666273_6667254_-\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	1.94456e-36
NZ_CP011271.1\|WP_082841757.1\|6681942_6684255_+\|HAMP-domain-containing-protein	gnl\|CDD\|185008	PRK15048, PRK15048, methyl-accepting chemotaxis protein II; Provisional.	1.4127e-95
NZ_CP011271.1\|WP_082841745.1\|6663732_6665301_-\|DUF1800-domain-containing-protein	gnl\|CDD\|378055	pfam08811, DUF1800, Protein of unknown function (DUF1800). This is a family of large bacterial proteins of unknown function.	2.60333e-136
NZ_CP011271.1\|WP_082841751.1\|6668827_6672460_-\|c-type-cytochrome	gnl\|CDD\|274225	TIGR02604, Piru_Ver_Nterm, putative membrane-bound dehydrogenase domain. All proteins that score above the trusted cutoff score of 45 to this model are large proteins of either Pirellula sp. 1 or Verrucomicrobium spinosum. These proteins all contain, in addition to this domain, several hundred residues of highly variable sequence, and then a well-conserved C-terminal domain (TIGR02603) that features a putative cytochrome c-type heme binding motif CXXCH. The membrane-bound L-sorbosone dehydrogenase from Acetobacter liquefaciens (Gluconacetobacter liquefaciens) (SP\|Q44091) is homologous to this domain but lacks additional sequence regions shared by members of this family and belongs to a different clade of the larger family of homologs. It and its closely related homologs are excluded from the this model by scoring between the trusted (45) and noise (18) cutoffs.	3.0982e-42
NZ_CP011271.1\|WP_082841742.1\|6660109_6660946_-\|cytochrome-c-biogenesis-protein-CcsA	gnl\|CDD\|307628	pfam01578, Cytochrom_C_asm, Cytochrome C assembly protein. This family consists of various proteins involved in cytochrome c assembly from mitochondria and bacteria; CycK from Rhizobium, CcmC from E. coli and Paracoccus denitrificans and orf240 from wheat mitochondria. The members of this family are probably integral membrane proteins with six predicted transmembrane helices. It has been proposed that members of this family comprise a membrane component of an ABC (ATP binding cassette) transporter complex. It is also proposed that this transporter is necessary for transport of some component needed for cytochrome c assembly. One member CycK contains a putative heme-binding motif, orf240 also contains a putative heme-binding motif and is a proposed ABC transporter with c-type heme as its proposed substrate. However it seems unlikely that all members of this family transport heme nor c-type apocytochromes because CcmC in the putative CcmABC transporter transports neither. CcmF forms a working module with CcmH and CcmI, CcmFHI, and itself is unlikely to bind haem directly.	9.74598e-07

>NZ_CP011271.1|WP_082841747.1|6666273_6667254_-|DUF1559-domain-containing-protein
MGALPSRRSAFTLIELLVVIAIIAILIGLLLPAVQKVREAAARMSSQNNLKQIGLATHNFLGVNNSFPLANYYPQTANPDGTYTSVDPNFHVISSGWSVILPYIEQDNMARRYNPKLHPFDTTDPDGDGFTNQMISNMPLKTFVAPADPQPTAVQYPGWSSYYWCSGNRRYQGVGQPGTGADGFTPSDGVILPGKEGARVTLLSITDGTSNTFLAGEGHHTLKGYSFTSGPLAGQARTGDTTWNYGHIYFSYQYTEAPMNTQQVASWAYDPARTSEDGKYSFRSSHIGGVNFLLCDGSVRFISQSIPMATYKALGSRAGGEVIGNY
>NZ_CP011271.1|WP_052555834.1|6666054_6666261_-|hypothetical-protein
MKRFALLAIALVSVGCGSSAPATGEPARKITWSEYQKMDAEQKDDPYVVDNLDDEAKKKRTEAGRKKK
>NZ_CP011271.1|WP_082841746.1|6665334_6666003_-|hypothetical-protein
MIRSLLVLTALVTAPFAALAHMVYVVPGADGKAIVVVFSDTLDPDTKVTTDKLAGLKLTGHTADGKSVAIEAKREPHQFTATLPAGTAVVSGDVIYGLMTKSEKPTLLVYHPKAVTGGATGAKTTVGESAALEVVPVTEGGKTRFRLLAKGKPVAGSEGNVLLPDGKKEKVTTDKEGYTGAFEGSGRFAAWFRHAETRAGEHDGKKFEEVRHYATLVADIAK
>NZ_CP011271.1|WP_082841745.1|6663732_6665301_-|DUF1800-domain-containing-protein
MTREPMWDVSAASHLLSRTSFGGTPQQAERLAARPLKDAVSALIEEAQRVPAPQKPAWVKEPWVNTERVYPETTNEERMENHRKAGERQSRERNELRCWWIDHAIRTPAPLREVMTLFWHGHFTTEARRMSVAQPLYTQNAALRAHALGNFRDLLEAVTLDAAMMMYLNMEDSDAKKPNENFARELLELFTLGIGNYSETDIKEIARALTGWTLSAPPGSKTRPLVEGAPRAFCRDGLVPTFVKEKHDAGEKTVLGKTGRFGAKEVLDIVATHPATAKFVAGKLVAFFGAADSKNELRDRVAEAFVASKGNIASVLAALLTSPEFFAKESRGTLIKSPVHLLVGTCRLLDLDVTATPSLAQVTAAMGQELFNPPNVKGWPGGRDWISSGTLAVRYHLPEALFDGTEPGGFEPLATDRFFALPADETARRDLIKRIQVADQLRKAERRKDGFKVTFVPEKAVGGKVPEKTEALVDVLLARLLAVPSRPDTKAALVDAVNQVEPAERVKLACRLILMTPEYQLA
>NZ_CP011271.1|WP_082841744.1|6662503_6663721_-|DUF1501-domain-containing-protein
MFPSIDRRRLLSVGALTATVPGFLSETGRLIAGDDRTPSLAANKDRVLVVIQLAGGNDGLNTLVPFRDDVYYKTRPKIAIARDKALKVTDEFALHPEMKELRALHDDGRLGVVSNVGYPNPNRSHFRATEIWETATPEKDVLTGWVGQYFDAECRGIASPMLGLQLGEKPALTFAHAKSRAVTLTNPRLFQWDTGTTGHAMDRLNRVRPTGNDQLDFLQRTANDTLMLSKKIQDALKDTRAATEYAPFNFSQSLKVVAQMIAADVPTRVYYVSLGGFDTHVTQVGRHAGLLQELSQGLGSFVKDLKALGHLDRTLVMTFSEFGRRVAENEQQGTDHGTAGVMFLAGGNVKAGIHGARPNLTDLDEGDLKFGTDFRRVYATVLANWFKADPKSILGGEFQPLPCLA
>NZ_CP011271.1|WP_082841743.1|6661180_6662392_-|GTP-binding-protein
MSGSSLPVTVLSGFLGAGKTTLLNHVLANREGLRVAVIVNDVSEVNIDGALVKTGGAALSRTDEKLVEMQNGCICCTLREDLLQEVARLAKEGRFDYLLIESTGVSEPLPVAETFTFEDETGHALSAVARLDTMVTVVDAANFLDDYFSPASLTDRNLALSAEDDRDVVNLLVDQVEFADVIVLNKTDLVSSEKLDQLEAVIRALNGSAKIIRSERGRVPLNEILNTKRFDFERAANAPGWMAVMRGDERPETAEYGISSFVYRARKPFHPERLHQFMVNDELTDSLLRSKGLMWIATRPQWAALWSQAGRVVELSPQAVWWADVPRDQWPTDSDERTEILATFEGEYGDRRQELVFIGQSLDQVAIRAALDAALMTEAEMCGGSVAWAQINDPLPEWLALDQ
>NZ_CP011271.1|WP_082841742.1|6660109_6660946_-|cytochrome-c-biogenesis-protein-CcsA
MTTTEIVKNIHHYCIGLSYLCAFLLEIARLLWPARGWRVAGLVFGAAGLFAHTAYLLVQQPSPAVPSGSVLMLAWVLALFYFYGTVHHARQAWAVFVLPVVIGLVVVSRILLTAEPEHAAFDVGEWASGERFWGGVHGLLILFASVGVSVSFLASMMYLIQARRLRNKVSPGTVVPMLSLERLETMNRRALNIAFPLLTAGLLVGTLLLPHGLSFGDNWLSLKVLSTAGLWLEFLVLLYLRYGAHVPARRLALFSIAAFGLLLVALAASHPFAIGGVK
>NZ_CP011271.1|WP_082841741.1|6658838_6660113_-|glutamyl-tRNA-reductase
MNLRAIGCNVASAPVGVRERLAFNAEKTQRALAELNSRFAAEAVILDTCNRVEIYLSRQETVAPLHIPLMAEFLSEVHGVAPAEIVPHLYEHADSAAARHLFRVASGLDSVVLGEGQIAGQVKDAYESAHKSTATGPLLNVLFPTALRVSKRVRTETGIAHGHVSVSSAAVDFVRQVFDTFTDKTVLVIGAGKMGRLTLKHLAELEPAAILVTNRNADRATAVARECGGVVVPWAQLDDALVRADIVLSTTGAPEPVVSAGRFDERVRPQRAGRPLVVFDMAVPRDFDARIHDGDTVSVFNVDDLAREADRSMGERKRHLSSAERIVESEVEKFVAEWNRRANGPVIGQLTAEVDRVRDSVLGPLLGKLNGKLTDKDKSDIEGAFRLFQNRLLHGPIAALREASSEGHSGGLREALRKLFGLKG
>NZ_CP011271.1|WP_082841740.1|6658081_6658780_-|Uma2-family-endonuclease
MATDVTALSTEVPPLRDGDRLTRTEFERRWDAMPEVKKAELVDGVVYMPALSRDHGVPHFGLIGWLWMYQTLTPGTEGADNASVRFDDDNMVQPDALLRVLESHGGRCRVTRDRYLEGGPELVVEIANTTADEDIGAKRDVYRRFGVQEYIVWRVADRALDWFVLRNGYYWPLAPSADGIIRSEVFPGLWLDSVATVAGDAARVLTVAQLGHGSPEHAAFVTELRRRAGYSA
>NZ_CP011271.1|WP_082841739.1|6657818_6658061_+|hypothetical-protein
MNPFQVYTPPMTGLTEARFFAAVATLEPPLPWPTGFRLLDWVEWWDLCQDEATDAQRAGAWALFANQPFFEVTRVEVSDE
>NZ_CP011271.1|WP_052555839.1|6668482_6668719_+|hypothetical-protein
MVRKFIFRKLLLALIAATALTANSGCLLNQYSSDPNIRMQQLLYQSEDLRQIQNEWRRFWFNDQPSHLTPERVHGGIY
>NZ_CP011271.1|WP_082841751.1|6668827_6672460_-|c-type-cytochrome
MRTLSLASLVLVLTGLMPNTPDATAAPPPPAPPEFAPNQTPTKPTPFPVKMVDQGTFDPKLKGTYLPEGFKAEIVVDAPDAINPVGMTFDPEGNLYVMEWRPDAVTGDRWFEVKETFRYRDGTVRQVATMKKFTTDLIKMFKYSPSTGKFEKPQIIISEELPSSILYHEGWLYVTGRGTVRRWKQSKPNGPWDVRETVAQGFCGFHHHQVSGLTLGNDGMLYLTSGDDDNFVEGSDGSRATVLRTGAVFRCRPDGSKMETYSIGYRNPYRDIAYDDKFNLFHTDNDQEDGSKFQGCRIMHVAEGADFGWRLRIGARCCQTDFVRGAVAGELPGKVPPMIKTGRGSPAGMLIYHDTRIPEQYRGLMYYPDVYRKLVRAYKVAPDGSTFKITNELEFMKSDDPLFRPCQMVTGPDGAIYVCDWRTNSGGAGKLSGDGTNGRIYRVTWAGTTEQPALARRGMDSWSKISKQSDADLLKTLAAPDLTDRVEARKELVRRGPKARDLVLKKFISGALDGDARLVALGVLQANWSPEVEDLFRLLMNDESGDVRRLAVDGLAYNAKPKDQRVYEAILKALGDREPAVRRAAALGLGRLGADGSGETLVNSLRQDAEADAYLKDAYVRAIERLGKPGIDALLTLAQTNDKGANLAAEVFLGLRTKPAADAIPEIMLHPHVTPAQREALVRSYTNYQFDPPVSLDPLADYLTKRPNEPANVLLAAVDVFTASGTALAPRAVNLVLDLLSRPDEMTRLSAIVAIESARIKEATPKLIEFVGDSNRTQVERVAAVKALRVLGDKAAVGPIKTLLSGQHPALLKAESLRALAALDIVSARTAAEPLLDQPDPTLLTEAVTVLAATKPGAKLIGERFVAKKLPREFFAQVNDAINKFADDPAFAKLRADVLRGGLLLSLEPGQVDKIRVLVNSKGDAKKGKELYLNTKVLACATCHRVEGVGGAVGPDLTRVWDTHTVEKLLESIVDPSKEIKEGFQTYRLVTADSKVYTGLKVKDDAKEVVIRDANGRDNRIAKDEIEALTPSKLSLMPDNVVSQITFEQFIDLLAFLKSKAEQESLRGLVVDSTVAGPFPADMSGSKIDPITEDKWKPLAAEPNGKMDLKAAFAPTNTPAVYVRAYVFAPKKQKAAIALDSTNPWRAWVNGSTAAPVETFEVELKQGWNVILVKVVNSGKPATLGVRVTGDGLRTAARPDTAPTSGTGGQ
>NZ_CP011271.1|WP_082841752.1|6672682_6674215_-|serine/threonine-protein-kinase
MSVPSSIEELLQLIRKSGMVEETRLSAYLQRRQLTRGVSVDPRELAEELVQDGVLTYFQSEQFLLGKWRGFTIGKYKLLERVGVGGMGQVFLCEHMFMRRRVAVKVLPPAKAEQPAALGRFYREARAAGSLDHPNIIRTHDIDQDGNLHFIVMDYVDGPNLLDVVKRFGPMDLQRAVSYVRQVAGGLEYAFRNKLIHRDIKPGNILIDRKGVARILDMGLARFLNDHTDQLTIKYDDKIVLGTADYVAPEQVANSHSVDIRADIYGLGSTFYFLLAGHPPFPTGTVSQKLLWHRTKEPAPIRQIRPEVPEGLAVIVGKMMAKDPKARYQTPAQIVAELEAFVSTGVPLPAAEEMPVLSPAAMEGTTEEECEAVIETPLDTAATLNAPVGSQVKAASAAAVLTPPALNPFGAPNASPWGTGPRLPPVNPLAKPGSRPVLAPLPSAPPRSEAPEAQTPATQREPFTPSNPFGGEVSPQTTTPPAKKSPWATLGAGVIIGVAIIIAVVLAKLL
>NZ_CP011271.1|WP_157469873.1|6674404_6675016_-|hypothetical-protein
MAVAPALAPPHEYPTFGLPSGSIRGILSVLICSFFWIVLLFPAGTTITVPLGHFFLLTLVFLAFASHPGTDARTSAVLPWLMRVVFVGGSAAVVAFAIWKDPELAAARLTPGTNEISQWPVLLGCLAGGFGVALFLRFVIGRNHNLFLSIRAWVGTVAMMLLFVETILQFLVLPNVAEKNLEALKIWEGIIIAVVAGYFGSRA
>NZ_CP011271.1|WP_052557395.1|6675311_6675743_+|50S-ribosomal-protein-L13
MSTTLANAATVQQNWVVIDATDLVVGRLAVTIANVLRGKHKVTYTPHCDTGDFVVVVNAEKVQFTGKKWDQKEYQDYSHYAGGQKITSAKEMLARKPEEIIRRAVKRMMPRGPLGYKQLGKLKIYTGNQHPHQAQQPQELKLK
>NZ_CP011271.1|WP_052555844.1|6675826_6676459_+|30S-ribosomal-protein-S9
MAEKKPAKAPKAHRTYYIATGRRKTAVARVRVTEGKGQVLINGKPFDQYFNEDKDRGAVLGPLKITDQLTRVDVFVTAKGGGITGQAGAVSQGLARAMKTMFSPADEQKAKVFGTTTVIKALRDEKKEQARAKAIAPKPAAPAAPVNEGTPLIPVGTAPAAAAPASPADIASGMVKKLRDSGYLTRDARMKERKKYGLRGARRGTQFSKR
>NZ_CP011271.1|WP_157469875.1|6676616_6677855_-|hypothetical-protein
MTFAPELMMLPLVLSLALSAPPDPLAFTVIGTTESAPTGKLRAVSLTLGAEVATTGGSQTVPRLVALRKPNTALPPFPTGAHIITAVGDRVPGKVTGGDAKALYFTHATTDESWSIALDAVAAVWLKPPAADTPSDPAKYTWLAGTPTRDALLYRNGDTVRGTLTGFTATGVKFTPDGGAARDVPLADLAAIGFNPRFVRPRRPKGPYAGLVLTDGTRLNVNEVALKGNALVCKAACGPAIEVPLTKLVALNVFQGPAVYLSDLKPKKAETVGFLGDGWAWAADRTVRGNPLFLQSGEGEETFDKGLGTHPKTVLTYDLAGKYGRFEAVVGLDAVTGKRGLADVRIRVDGKEVPLPELKALAAGNAIPVKVDVRGAKELALVIDFGPAGDVQADVNWGTARLVEQPATALGQ
>NZ_CP011271.1|WP_082841755.1|6678469_6679447_-|transporter
MDQRLSALLMAVLVLCTGCVAANRPLPEYRTRQALFSWKGEKESDKDDKKEPDKNEAGGKEPGDDEPNGDKNGGERKSEEPDPIVTERPDFTNSSRTIGRNRIQLESGYTFTSDGRGASRMNSHAFLEALVRVGIFADWFEVQIGQNFLHTRAADPANPAGVNLQTGPQDLYLASKFALTKQDGILPETAVTLQMTLPTGSREQGSNKVLPGLLFLYSWDVIPDRISLAGSSVFANAEEDDHGYFSYAQSLSVGYTLTKRLSAYTECFALFPSGATPTQVGPEYYYNGGFLYQVTPNFQLDIRFGVGLNKHADDFFTGVGFAIRY
>NZ_CP011271.1|WP_082841756.1|6679683_6681660_+|HAMP-domain-containing-protein
MSWFRNLKMAAKLGISFAILVLLVACTGGLGLHGLGQVNDRADDIAKHADGLNHVQEANGELLRISRAVRNAILDTDTASIDKRAADIRRADQRFRTEFEEYRRTIVKNDTKIKAAEVERQFNELRPLQDEIVTLARAQKDEEAKAPLPRIRAIADSMEEKINALVESKQELIKQAQTDASATYAQLRGIVTTVVIGACALAVALGVGLSRLTARPLQKTMHVLEAVAKGDLTHRAEVTSTDEIGQMSAALNVAIGALVAAKEAERAQVERDRERAAREAAEARERTEREAAATRAQAEVERAQAAELKSRIDTIITTVSSLAAGDFTQEIPDLGADSVGQMAHSLNKAVVSVRTALEGVREVSEQLADASSQLSAVSDEISTGAQEQASSLEETASTLEEITATVRQNSDSAQQARQLASNSKGVAERGGQVVGNAVDAMSEINQSSKKIADIITTIDEIAFQTNLLALNAAVEAARAGEQGRGFAVVASEVRNLAQRSATSAKEIKSLIEDSVKKVDAGTELVNLSGSTLGEIVTSVKRVTDLITEIAAAGKEQSTGIEQVNKAVSQMDSVTQRNASQTEEMSATAQALTDQAAQLRDLVARFKLSDARPAPRSTSKPVRAKAPATKPRPAVARAMSKTHERDSFSGTGNDGFTEF
>NZ_CP011271.1|WP_082841757.1|6681942_6684255_+|HAMP-domain-containing-protein
MKTFNNLGVGTRLIVGFLLLAVASAGVGYFALTSMSDMNAALENANANLIPSINALNDMRGKGVNTIQRNERTLILSARSKNEEAYRGAVTGLEKAWVNIRDGYTRYESYPMIEREKQLWGEFRPRLEEFRRDHEATMAALKSGDLDKAEKLCLGSTANANKMGDALDALIDLQKEVGEKDAGEARKEYAAARTTMFVVIGGAMLAALGLGIFFRGLVVRPLAATVQVLRAVSTGDLTQKAVVTSTDEFGQMGAALNATVQGIHIALQQDKVSWEAVGKQREQNADFAAQIVAIGKSQAVIEFKLDGTIVSANENFLRTVGYSLPEIQGRHHSMFVPPALASGSEYRDFWSRLNRGESVAGEFKRIGKGGKEVWIQASYNPIPDLNGKPYKVVKYATDITAAKNMEHKVKEDTIELKQKVATIMTAVNALAAGDFTQEAPDLGTDEIGQMSAALNKAMISVREALEGVREVSEQLADASGQLSSASDEISTGAQEQASSLEETASTLEEITATVRQNSDSAQQARQLASNSKEIAEKGGQVVGHAVGAMSEINEASKKIADIITTIDEIAFQTNLLALNAAVEAARAGEQGRGFAVVASEVRNLAQRSATAAKEIKSLIEDSVKKVDAGTELVNQSGSTLGDIVTSVKRVTDIITEIAAASKEQSTGIDQVNKAVSQMDSVTQRNASQTEEMSATAQTLTDQAGQLRDLVARFKLGHDERPAPKPTHKAPRSKPSNPKPRPAVARAMSKTHELDRLGGGGGGGDDGFTEF

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Crispr_ID: NZ_CP011271_22

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_22

7042173-7042273

Orphan

Consensus_repeat	Method
AACAGGTGAGCCGGCCCGGAGTTCACAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_22

>merge|NZ_CP011271|22|7042173-7042273|CRISPRCasFinder
AACAGGTGAGCCGGCCCGGAGTTCACACGCTTGTACCGGCCTGATGATTGTTGGCAGTCGCGACGTAATAGCAAACAGGTGAGCCGGCCCGGAGTTCACAC

>NZ_CP011271|22|22|7042173-7042273|CRISPRCasFinder
AACAGGTGAGCCGGCCCGGAGTTCACAC	GCTTGTACCGGCCTGATGATTGTTGGCAGTCGCGACGTAATAGCA
AACAGGTGAGCCGGCCCGGAGTTCACAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_082841958.1\|7031063_7031579_+\|TIGR02996-domain-containing-protein	unknown	unknown	gnl\|CDD\|274381
NZ_CP011271.1\|WP_052556481.1\|7053931_7054750_-\|RNA-polymerase-sigma-factor-RpoD/SigA	unknown	unknown	gnl\|CDD\|223642
NZ_CP011271.1\|WP_082841966.1\|7042535_7043672_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|235596
NZ_CP011271.1\|WP_157469946.1\|7055440_7055614_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841970.1\|7050114_7052784_+\|PAS-domain-containing-hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl\|CDD\|237425
NZ_CP011271.1\|WP_052556462.1\|7037878_7038091_+\|carbon-storage-regulator-CsrA	unknown	unknown	gnl\|CDD\|376847
NZ_CP011271.1\|WP_082838323.1\|7031588_7032875_-\|IS701-family-transposase	unknown	unknown	gnl\|CDD\|379252
NZ_CP011271.1\|WP_157469940.1\|7044176_7046789_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223864
NZ_CP011271.1\|WP_157469944.1\|7054904_7055438_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082841969.1\|7048652_7049915_+\|PQQ-binding-like-beta-propeller-repeat-protein	unknown	unknown	gnl\|CDD\|274511
NZ_CP011271.1\|WP_157469938.1\|7035313_7036072_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_157469942.1\|7047089_7047494_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_157470490.1\|7039278_7040694_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
NZ_CP011271.1\|WP_082841963.1\|7038274_7038931_-\|DUF1080-domain-containing-protein	unknown	unknown	gnl\|CDD\|368908
NZ_CP011271.1\|WP_082841965.1\|7040934_7042167_+\|DUF3754-domain-containing-protein	unknown	unknown	gnl\|CDD\|372201
NZ_CP011271.1\|WP_082841962.1\|7036364_7037405_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237512
NZ_CP011271.1\|WP_082841959.1\|7033114_7034098_-\|WD40-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|238121
NZ_CP011271.1\|WP_082841968.1\|7047574_7048201_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|379399
NZ_CP011271.1\|WP_162271881.1\|7034105_7035023_-\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NZ_CP011271.1\|WP_082840381.1\|7052931_7053921_+\|transposase	unknown	unknown	gnl\|CDD\|379252

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_082841958.1\|7031063_7031579_+\|TIGR02996-domain-containing-protein	gnl\|CDD\|274381	TIGR02996, rpt_mate_G_obs, repeat-companion domain TIGR02996. This model describes an abundant paralogous domain of Gemmata obscuriglobus UQM 2246, a member of the Planctomycetes. The domain also occurs, although rarely, in Myxococcus xanthus DK 1622 and related species. Most member proteins have extensive repeats similar to the leucine-rich repeat, or another repeat class or region of low-complexity sequence. This domain is not repeated, and in Gemmata is usually found at the protein N-terminus.	5.07222e-14
NZ_CP011271.1\|WP_082841966.1\|7042535_7043672_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	2.26944e-126
NZ_CP011271.1\|WP_052556481.1\|7053931_7054750_-\|RNA-polymerase-sigma-factor-RpoD/SigA	gnl\|CDD\|223642	COG0568, RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription].	1.25714e-77
NZ_CP011271.1\|WP_052556462.1\|7037878_7038091_+\|carbon-storage-regulator-CsrA	gnl\|CDD\|376847	pfam02599, CsrA, Global regulator protein family. This is a family of global regulator proteins. This protein is a RNA-binding protein and a global regulator of carbohydrate metabolism genes facilitating mRNA decay. In E. coli CsrA binds the CsrB RNA molecule to form the Csr regulatory system which has a strong negative regulatory effect on glycogen biosynthesis, glyconeogenesis and glycogen catabolism and a positive regulatory effect on glycolysis. In other bacteria such as Erwinia caratovara RmsA has been shown to regulate the production of virulence determinants, such extracellular enzymes. RmsA binds to RmsB regulatory RNA.	1.90219e-25
NZ_CP011271.1\|WP_082838323.1\|7031588_7032875_-\|IS701-family-transposase	gnl\|CDD\|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.63533e-46
NZ_CP011271.1\|WP_157469940.1\|7044176_7046789_+\|hypothetical-protein	gnl\|CDD\|223864	COG0793, Prc, Periplasmic protease [Cell envelope biogenesis, outer membrane].	4.88213e-83
NZ_CP011271.1\|WP_082841969.1\|7048652_7049915_+\|PQQ-binding-like-beta-propeller-repeat-protein	gnl\|CDD\|274511	TIGR03300, assembly_YfgL, outer membrane assembly lipoprotein YfgL. Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking].	7.22628e-18
NZ_CP011271.1\|WP_082841970.1\|7050114_7052784_+\|PAS-domain-containing-hybrid-sensor-histidine-kinase/response-regulator	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	4.11793e-92
NZ_CP011271.1\|WP_157470490.1\|7039278_7040694_+\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.13979e-29
NZ_CP011271.1\|WP_082841963.1\|7038274_7038931_-\|DUF1080-domain-containing-protein	gnl\|CDD\|368908	pfam06439, DUF1080, Domain of Unknown Function (DUF1080). This family has structural similarity to an endo-1,3-1,4-beta glucanase belonging to glycoside hydrolase family 16. However, the structure surrounding the active site differs from that of the endo-1,3-1,4-beta glucanase.	4.64361e-28
NZ_CP011271.1\|WP_082841965.1\|7040934_7042167_+\|DUF3754-domain-containing-protein	gnl\|CDD\|372201	pfam12576, DUF3754, Protein of unknown function (DUF3754). This domain family is found in bacteria, archaea and eukaryotes, and is typically between 135 and 166 amino acids in length. There is a single completely conserved residue P that may be functionally important.	8.29604e-20
NZ_CP011271.1\|WP_082841962.1\|7036364_7037405_+\|hypothetical-protein	gnl\|CDD\|237512	PRK13800, PRK13800, fumarate reductase/succinate dehydrogenase flavoprotein subunit.	0.00538449
NZ_CP011271.1\|WP_082841959.1\|7033114_7034098_-\|WD40-repeat-domain-containing-protein	gnl\|CDD\|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	6.47184e-65
NZ_CP011271.1\|WP_082841968.1\|7047574_7048201_-\|thioredoxin-family-protein	gnl\|CDD\|379399	pfam13899, Thioredoxin_7, Thioredoxin-like. Thioredoxins are small enzymes that participate in redox reactions, via the reversible oxidation of an active centre disulfide bond.	3.48371e-05
NZ_CP011271.1\|WP_162271881.1\|7034105_7035023_-\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	1.46461e-56
NZ_CP011271.1\|WP_082840381.1\|7052931_7053921_+\|transposase	gnl\|CDD\|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.36374e-13

>NZ_CP011271.1|WP_082841965.1|7040934_7042167_+|DUF3754-domain-containing-protein
MLREHYIPVRVADLIGFLCAESGPLHNQVLTAEEQAAFRRFASTVASHVHTIYQTEIRQLKDAYAAFDPDADPKPLDPPTGEKRAAALDRLFDTFIHLMGRANYRRVTRDEMEQITRGASAWGVDMDVTWDAFEKVEVFYRGRGYGKRTKRGLVRFWRKYAIELPTFARVAVIFKQRAHKRLGDDADTKSVFLKLFKDMPQIDIEMLLPGGRIRMLKLDRLKLGGSLTSSAAYVVWKLSTFPLLSLLGGFATSTLFALWTPIALIGGYGYKTWYSFQSSRQTYTHQLTQSLYYQNLDNNSGVMFRLLDEAEEQEIREALLAYFYLWRYGGDEGWTTEQLDFYIEQDLKNRLPAHVNFEIIDALTKLIRGGLVRKHNHRYRAVPIHEAQAKLNAIWDGYARNGPPHLLPGE
>NZ_CP011271.1|WP_157470490.1|7039278_7040694_+|MFS-transporter
MFPVIGAQALSELLKVAPDSDAVRLWSGRMLWIAALAGGVFGLLGGMLIDRLGRKTVMVGSILAYSLSPVAAAYSTELWQLILFRCTTFIGVCVELVAAVTWLAELFTDKRQREMVIGWTLACASLGGIFVTEVFNEIAAFMRLHPEGVSWLPVPPAAWRYTLLTGLIPGALILLLMPFVPESRVWKERKLAGTLKRPSFGELFSPGLRKTTIVTTLLSACGYAAAFGALQLTPLQMTPGLPVLDPIKKEHGPAVKAATGKVKAADEKLGKAETESDKAAATEQKTAAQKELRAAQKPITDEINATRGNIQRWQELGGLTGRILFAILLLYVASRVLIRIFLLPGVVLFPVAYLVLYQGDYTVFAAAIFLCGLVTIAQFSYVSEYLPKVFPVHLRGTGSGFATNVGGRMLGTMAATLNTELLAPMLSGEGNPAKVAKAAAIIGSAVYAIALLLSFMLPTPKEETPPAPPAA
>NZ_CP011271.1|WP_082841963.1|7038274_7038931_-|DUF1080-domain-containing-protein
MRRPRLFRAAPLAVVALVLAPQFVRADDTEDFLKPENWEGRTDLWKVDPKAKTVVGETTEDPKYNTFFCSKKKYSDFELSCKVQLRDGVGNSGVQIRSELFDAKMFKVKGPQVDVGKGYWGSLYGEGVGGMMKASSPDTIKKAVKESEFNDYLIVAKGTKITIKINGETMVDQDFAKLPGKDAKDAPKDGIIAFQVHSGYPKMRVEFKDIKFTDLSKK
>NZ_CP011271.1|WP_052556462.1|7037878_7038091_+|carbon-storage-regulator-CsrA
MLVLSRKKNESIVINNDIVITVVEIRGDKVRLGIEAPKDVPVHRQEVFEAIHGSKAPVVATKTDDTEPTA
>NZ_CP011271.1|WP_082841962.1|7036364_7037405_+|hypothetical-protein
MTRKQWMVRAGGGLALVVVVGGIWAGFNASVIRAKLTARQLAGATTDEERTRLADQLVGYGTPGFDQLIDFVKSGDEAPRAAATAALDKHLNSLPDEDARAINISGSVLEAFPSANEAGKRAILTLVPVVLKRTGSAHADRCRGVVAEGLKLPDLESRLAAVRLAIHPEIGLRTEVVPFLSAKEPELRGASLFAVAANSDGDQVLGDEELFRWLHDPDAGVRKVCYDALVGRERSEVDIALGRRLTHTDPNERLKLLLDLRYDNDVADPEPWLERLSRDPEPAVRAGAARVMAEVAALRKIPCPAWIARVTDGDVHPTVRFVATYYRQLPVTPPNGVVPAGGLPQK
>NZ_CP011271.1|WP_157469938.1|7035313_7036072_-|hypothetical-protein
MTGPAKVLGVLLGGTVAGVVQAAPPASTSDDPGAPTPAMPAAMPAALPNTAGAVRVNLADVVHADYRDAVMKVVQKPTVSTRASAPDVICTVSMYEWLFDHPDRVAAAWHRMKVPAVPISDAGNGLFAWTDEHGSEVVWRTVGTFQDGRVWYATGKVKPGAAAPAVPVKAVAILTHPRKATKDGVASFSTSVQVFLVSDSKAATLALRLIGPAAPRVAEQGAEQFLEFFNGIADYVQKNPTKADALLAPAKK
>NZ_CP011271.1|WP_162271881.1|7034105_7035023_-|DUF1559-domain-containing-protein
MSKYHPKSPRGFTLIELLVVIAIIAILIGLLLPAVQKVREAAARMKCQNNLKQIGLAMHSYHSRMERFPAGFSSGAASTNGDGTGPGWGWAAVLLPDLEQDNLARTINYALDIRDSANASARVRQIPVFLCPSDNPTSPTFNAVDESGTVLTTVAFANYVGVGGTFEVTGYPDTANGVLYRNSKVRAGDITDGLSNTLMVGERGSKRSPQTTWVGAVTGCANPPVNPAYEFEGPPTLCLTNTGEAVDGRVPNNALDHVEDSNSNHTQGVNFLLCDGSVRVIQNTVNPVTWERLGTRAGGEVIGDY
>NZ_CP011271.1|WP_082841959.1|7033114_7034098_-|WD40-repeat-domain-containing-protein
MTTDTATSSRRGWVRGAAFLLPVILVSAGVWLLWPRGQERVSLSAGGSVRVVAVSPDGALIAAAGEDKVIRVWDAGATTTKFTLEGHTGKVFGLAFSPDSKTLSSCGDDRTVRLWDAATGAPGAVINASDATVECVAFAPDGKTLASAGGDHIVRLWTVPDGKPIRTLKGHTRRIHALAFADSKTLASAGEDGGVRLWNWLAGALIGPLPVEKHRVYALAVSADGKTLAAAATGGTRWWTLADKSERPKLGSAGGTRAVAFDCDGKFLATGHEDGTVKLWTAADGAEVKTLTGHRGAVFGVGFTPDGKTLVSAGSDGTVKLWDVPVK
>NZ_CP011271.1|WP_082838323.1|7031588_7032875_-|IS701-family-transposase
MTDQEIARLGPAFAHYLGRYRGCFLQKRTADHFDNYGRGLLSELPRKSVEPIALACGTAVRTLQEFLTTADWQHESAREQLQRRCAEVLDGLPGDDLGTVGVIDETSAVKKGDRTPGVQRQYLGCVGKIDNGIVTVHVGVAKGTFQALLDADLYLPESWNADRPRCQAAGIPDEVRYRPKWRIAYEQLVRLDAHGVRFDWLVFDEGYGSKVPFLRALDAVGQPFVGEVPVSFSVTTAARDEPRRADSVLRADDARRGRRFRVSRKTVGDTRWRATSRLIEVRGCRWMLVVAQNESTAEVKYFVTNATDEPLARVLRVAFRRATIEHQFRVAKSEAGMTHYEGRQYVGLVRHLILGLVVLGFVSIHTDRLRGEKTAGDDGAGVPGAERPMCGDVPSEARDAGTTARRRGHPLPPTAERAGHESAQKMAT
>NZ_CP011271.1|WP_082841958.1|7031063_7031579_+|TIGR02996-domain-containing-protein
MSDEAGFLKAIADRPGERATRLAYADWLEENGRPQEAEFLKVQFQIEEMNTRLIELGGQLDAKWLTAIGNVRTESLQFTLRTRRVLTLCELRQWDFYASLLEDRSMIEEVQRIVAEEESRQGQRPYLIQHIEQERPSSIKPLEMLPTDGLWEFLPTSESLGVTLPTTTARV
>NZ_CP011271.1|WP_082841966.1|7042535_7043672_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MFPESLLADRTRAVEVSGVRKVFELSRSLKDPVNLSIGQPHFDVPEAIKNAAKAAIDGNRNGYTVTQGIPELCSRLLADAQARFPAPAQVPPGGERDVLVTSGTSGGLVLALLAVVNPGDEVITADPYFVAYPNVVALAGGKLVTVDTYPDFRLDVDKVAAAITPRTKAIVLSSPSNPTGAVLNAATQKALAELARDRGILLISDEIYRGFHYDGAPQSPATYDPNVLVIEGFGKTYGITGWRLGWAHGPKRLIQEMAKLQQCTFVCAPSIVQWGGIAALDFDVSGIVADYKRKRDLLVEGLKGAFEFVVPGGAFYLYPKAPWGTATEFVTEAVKHNLLIIPGSVFSERDTHFRVSYAATDETLTRGIEILRTLAKKK
>NZ_CP011271.1|WP_157469940.1|7044176_7046789_+|hypothetical-protein
MNARVWILGAIAAVALAVGPQPRASAAEGREGAAKAQGPYVVIVGVGEFKDKAISPRPTADADAKALHAMLTDKKYLGVSADRAKLLLSKDATREAVVKAVETAVGSTGPEDTVVLAFFGRGTSAGDKPCIFTSDSTVKERAKTALQITDLEPAFKKLKNQNLLLMMDIQYRGGIDAGTEKIVEPSWGEIMKLVFGDEKDDNMLPPNRVMILGNPPFQDALTQGDHGLFYSVLSAGLGGKADQAPYNEGYESDGIVTTRELLKYLEKEIPAAARATGKTDKEKELEPVFVGRGASKFWLTRNPAETASVKKRIETVETLTKDNKLTPDLSKEAVNLLFQMPKLKWSQELRKAYQKLADGGTVADLEAARKKLLEGLKLQTEDATEYAKKVAPAISKLSAEYIKPLSRGELTALAIRGVFTEADEAIPADIAAAIKAPQEISDERGRELLAEARLRLGKREDLDGEKAADVTIRALIGSLHDPYAGYFTKEEWLRTQGQLFGRFPGVGIIIRREAVRDGLLVVTPIKGSPAFRAGIQAGDLITEIRLEVDKQGKALPDDAKKVHSTKGLKTDDAVNLITGKPDTPVALVIQREGEKEPKVFRLTRNYVMVETVHGVKRDEKNDWSYYIDEKSKIGYLHLSQFISISDDMGTTADIKRALASMKRSGLNGLVIDVRNNPGGSLKGVIDICELFVGREAIVTTKERGGAGATFTYSGRAAGDKSFPIAVLINGNSASASEILAACLQDHSRATIIGERTYGKGSVQHVEPYDPTDGRIKYTVARYYPPSGRNIDKVAMEQSTELKTKDEWGVKPDAGFEIKMTREELTDWFEYSRDLEIIPPAGKKPPVVDPAKDKQLSKALEHLRGLIKDKK
>NZ_CP011271.1|WP_157469942.1|7047089_7047494_+|hypothetical-protein
MLRRSVLIAAAAVLVAAQTGCRSNCSDWRPGWFTSHSRSAAPGQTVGRNSGCFDMATGQPVPCPPGTPANVVPGGAFPSVVPGGPRTDILPMPAENGLIPAPAIPLPAPGETNNNVVLPFPTTPGTPVKNGSNK
>NZ_CP011271.1|WP_082841968.1|7047574_7048201_-|thioredoxin-family-protein
MTTTILAVIALSGSLVPAAKPEFQAQTDYSQALRQAAAEGKPMAVLIGNGNAFAKVMGDAALPEATAKLLRDKFVCVTVDVNTVAGKELAGQFQLTDGLVISSAGGTHQALRQSGSISTSDLTKHTATFANATGTPAMTVTVGAPYTVYPTGYSPVYRGTVIQGGCSGGSCGTVIQGCSGGSCGTIIQGGYSFPSIGSCPNGRCPTPR
>NZ_CP011271.1|WP_082841969.1|7048652_7049915_+|PQQ-binding-like-beta-propeller-repeat-protein
MHRRAFLTSLPASALAAQLSVAESSKIAVAATDWPWWRGFTRDGIAAPGQKVPLEWSKDKNVVWESPIPGRGHGSPIVVADRVFLATADQDAETQLLLCLDRKTGRQIWQTEVHKGNFVKGGNAKSSHASSSPACDGERVHINFLNGGAVYATAFDLNGKKVWQTKVTDYALHQGFGSSPTVFGPLLLVTADNKESGLLAGLDRETGKVVWSRKRPKAPNYASPIIVKVDGKDQLVLTGCDLVTSLDPLTGKENWEIKGATTECVTSTVTDGKHVFTSGGYPKNHVAAVKIDGSGVAWENKSRVYVPSMLFHAGHLYAVMDEGNAICLRSDTGAEVWKGRLGGTFSASPVMVGEHVLAVNEIGRTFVFKATPTEFEILAENRLGDEVFATPAVSGGRVFMRVATKDKGRREEKLYCLGTN
>NZ_CP011271.1|WP_082841970.1|7050114_7052784_+|PAS-domain-containing-hybrid-sensor-histidine-kinase/response-regulator
MTAYDQAELAQALLSEIGDALFLLDPDTDRLLEVNPVALRLTGFSRAEVLQLSATHLFRFEAVGGTQRLKGAFTKTVVFHGQDGFLLRTKSGPWLPVSLTVSRLHLPPRPLGLIIARDDRERRSALAQARRVESELRTVLSSSPAALWSAERAPGPDVFSGWLFRYVSPLLARIAGRPPEFFDHPFKWADVVHPGEREAYRQTLHRLLTWGDDCEQVYRVQTAEGGARWVRDRLQVVRDATGRPTRLDGCVTDVTEQRAAEDAVRQSEERFRALVEKSRDGILLLDDRGTIKYATSAVKLILGFPPEAVTGLNMFAFVHPDDAAGARKRFAYSLGHPGEDVPGTYRAIAADGGARAIEMNAVNRLDDPSVQAVVVNYRDVTERDATTRELAEQHALLEGLFASVPDVVCYKDREGRFLGGNPAFEEFAGQPTAALVGRRCDEVFTDEWAVRMRAAEELVTATGRTERCKEWVTYPTGRKALLDTVIAPLRGDEDGATVGLIVVGRDVTDQERLEDALRQSQKMEAVGRLAGGIAHDFNNLLTVVLGNLELVRCGAATGPDAAELLLATERAAKQAAELTKQMLGFARRQPLRTAVVDLNALVRESLELFRRSIDPRITVRFAPDPDLRPVAADPVQVQQVVMNLCLNARDAMPDGGTLTLETADADPPSDAGAGRFVRLSVSDTGSGMTEEVRAKIFDPFFTTKGVGQGTGLGLAVVYGVATAHGGLVEVTSAPGAGSRFDVYLPRGIASDERTGFRSEVRTDFPRGGGETVLVADDEAGVRDLARVALEMSGYNVLLAGDGAEAVNTFQQANGRVKLAVLDASMPKLSGRQVFEAIRRINPEVKVLFASGYHGGGLLPEDEPPGTRRLNKPYIPSQLAAVVQEMLTVV
>NZ_CP011271.1|WP_082840381.1|7052931_7053921_+|transposase
MNPPRATAEDYIAFLVATPGEGTATEMGRCQPARPDAPAHDAFTRLLNRLEPEPEALWDEVRPLLPTDGVLVFDDTVLDKPFARHMGLVGRFWSGRHKRVVPGINLVTALWTDGDALWPCDYRLVDKAAGDGTKNDQFRDMLRVAAGRGLAPRCVCFDCWYSGKDNLKAVRALGWTFVTQVRCNRKVNPDRTGNRPIEECDIAASGTVVHLEGFGRVKAFRIATTDGGTEHWITNDLSMDEGARLMFAERAWGIEEFHRGLKQHTAVDRCQTRMGRAQRNHIGFALRAFVRLEWHRFNTGVTWFAAKLAIIREAVRQFLAQPVYRLPTA
>NZ_CP011271.1|WP_052556481.1|7053931_7054750_-|RNA-polymerase-sigma-factor-RpoD/SigA
MRTENNARTAFSTYLSEIDHTPLLSAPEERELGARVLNGDVQARDRMVRANLRLVVNIARGYTGKGLALDDLVSEGNMGLLRAVEGFEPSMNTRFSTYASYWIKQSIKRAIVNTAKTIRIPAYMAELLTKWRRATNQLSDELGRPPTHDEIAKFLGLSKKKLAIIKKAIRVANAGSQADQGDAGWSIEEMLMDGRSDTPESEMGKSDDLKQVLHLLDKMDPREATVLRMRFGLNDEEPRTLKEIGECLGLTRERVRQIENEALSKLSDGMTV
>NZ_CP011271.1|WP_157469944.1|7054904_7055438_-|hypothetical-protein
MRYSAFIRDGGQLGTVGADELERWYRFHLGCGNCMRRSHPQRYVRKRWNPGRSAPDPRGRIASSCRAHETLWLQLRGAHELVLPPLTNMTAGAPLGPFLLAEPLMDNLSEFTSSLDGGWVQRLMSQKGEVIDKAARVLIKSLGGLLVLQERLTEQWNAERALARPPEQEPGAPAPRA
>NZ_CP011271.1|WP_157469946.1|7055440_7055614_-|hypothetical-protein
MRNTESGELVQLAHGAAELTGTDFEYRKRRYQRIDAESLFKDVAAESALILRVRSRA

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Crispr_ID: NZ_CP011271_23

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_23

7164131-7164249

Orphan

Consensus_repeat	Method
GGGGATTCAGTGCTGGTACTGATGCCACCCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_23

>merge|NZ_CP011271|23|7164131-7164249|CRISPRCasFinder
GGGGATTCAGTGCTGGTACTGATGCCACCCTCTGAAGGTGGACGACGCTGGTTCGATTCCAGCCCCGGCAACTGTGCGATCGATTCCGGGGGATTCAGTGCTGGTACTGATGTCACCCT

>NZ_CP011271|23|23|7164131-7164249|CRISPRCasFinder
GGGGATTCAGTGCTGGTACTGATGCCACCCT	CTGAAGGTGGACGACGCTGGTTCGATTCCAGCCCCGGCAACTGTGCGATCGATTCCG
GGGGATTCAGTGCTGGTACTGATGTCACCCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_052556633.1\|7163384_7163690_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842044.1\|7174504_7176907_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224276
NZ_CP011271.1\|WP_052556637.1\|7167106_7167391_-\|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl\|CDD\|198403
NZ_CP011271.1\|WP_082842038.1\|7160300_7161923_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NZ_CP011271.1\|WP_082842040.1\|7169061_7171482_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_157470492.1\|7158386_7159481_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	unknown	unknown	gnl\|CDD\|224029
NZ_CP011271.1\|WP_052556620.1\|7152773_7153841_+\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NZ_CP011271.1\|WP_082842045.1\|7176919_7177444_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842043.1\|7174025_7174373_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052556624.1\|7155140_7156121_-\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_CP011271.1\|WP_082842039.1\|7165426_7166641_-\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|223479
NZ_CP011271.1\|WP_082842042.1\|7172900_7174022_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842033.1\|7154078_7155011_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|381389
NZ_CP011271.1\|WP_082842034.1\|7156272_7157166_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842037.1\|7159487_7160267_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|259883
NZ_CP011271.1\|WP_082842035.1\|7157221_7157929_-\|DNA-alkylation-repair-protein	unknown	unknown	gnl\|CDD\|132880
NZ_CP011271.1\|WP_082842041.1\|7171644_7172823_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|336785
NZ_CP011271.1\|WP_157469967.1\|7167491_7167653_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082843447.1\|7162138_7163134_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380413
NZ_CP011271.1\|WP_052556639.1\|7167745_7168906_-\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|283431

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_082842044.1\|7174504_7176907_-\|hypothetical-protein	gnl\|CDD\|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	3.15418e-29
NZ_CP011271.1\|WP_052556637.1\|7167106_7167391_-\|GIY-YIG-nuclease-family-protein	gnl\|CDD\|198403	cd10456, GIY-YIG_UPF0213, The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1. This family contains a group of uncharacterized proteins found mainly in bacteria and several in dsDNA viruses. Although their function roles have not been recognized, these proteins show significant sequence similarities with the N-terminal GIY-YIG endonuclease domain of structure-specific endonuclease subunit SLX1, which binds another structure-specific endonuclease subunit SLX4 to form an active heterodimeric SLX1-SLX4 complex. This complex functions as a 5' flap endonuclease in yeast, and has also been identified as a Holliday junction resolvase in human.	4.74898e-33
NZ_CP011271.1\|WP_082842035.1\|7157221_7157929_-\|DNA-alkylation-repair-protein	gnl\|CDD\|132880	cd06561, AlkD_like, A new structural DNA glycosylase. This domain represents a new and uncharacterized structural superfamily of DNA glycosylases that form an alpha-alpha superhelix fold that are not belong to the identified five structural DNA glycosylase superfamilies (UDG, AAG/MNPG, MutM/Fpg and helix-hairpin-helix). DNA glycosylases removing alkylated base residues have been identified in all organisms investigated and may be universally present in nature. DNA glycosylases catalyze the first step in Base Excision Repair (BER) pathway by cleaving damaged DNA bases within double strand DNA to produce an abasic site. The resulting abasic site is further processed by AP endonuclease, phosphodiesterase, DNA polymerases, and DNA ligase functions to restore the DNA to an undamaged state. All glycosylase examined to date utilize a similar strategy for binding DNA and base flipping despite their structural diversity.	2.27841e-19
NZ_CP011271.1\|WP_052556639.1\|7167745_7168906_-\|VWA-domain-containing-protein	gnl\|CDD\|283431	pfam05762, VWA_CoxE, VWA domain containing CoxE-like protein. This family is annotated by SMART as containing a VWA (von Willebrand factor type A) domain. The exact function of this family is unknown. It is found as part of a CO oxidising (Cox) system operon is several bacteria.	1.67333e-35
NZ_CP011271.1\|WP_082842033.1\|7154078_7155011_-\|hypothetical-protein	gnl\|CDD\|381389	cd19163, AKR_galDH, L-galactose dehydrogenase (L-galDH) and similar proteins. L-galDH (EC 1.1.1.316), also called L-galactose 1-dehydrogenase, catalyzes the oxidation of L-galactose to L-galactono-1,4-lactone in the presence of NAD(+). It uses NAD(+) as a hydrogen acceptor much more efficiently than NADP(+).	5.23445e-140
NZ_CP011271.1\|WP_052556624.1\|7155140_7156121_-\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	6.27604e-56
NZ_CP011271.1\|WP_082842039.1\|7165426_7166641_-\|amidohydrolase-family-protein	gnl\|CDD\|223479	COG0402, SsnA, Cytosine deaminase and related metal-dependent hydrolases [Nucleotide transport and metabolism / General function prediction only].	3.34928e-50
NZ_CP011271.1\|WP_052556620.1\|7152773_7153841_+\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	1.21315e-22
NZ_CP011271.1\|WP_082843447.1\|7162138_7163134_-\|hypothetical-protein	gnl\|CDD\|380413	cd07010, cupin_PMI_type_I_N_bac, Phosphomannose isomerase in bacteria and archaea, N-terminal cupin domain. This subfamily contains type I phosphomannose isomerase (PMI; E.C. 5.3.1.8; also known as mannose-6-phosphate isomerase) found in many bacteria (e.g. Bacillus subtilis) and archaea. PMI catalyzes the reversible isomerization of fructose-6-phosphate (F6P) and mannose-6-phosphate (M6P), the first committed step in the synthesis of mannosylated glycoproteins. The active site, located within the N-terminal jelly roll-like beta-barrel cupin fold, contains a single essential zinc atom and forms a deep, open cavity large enough to contain M6P or F6P. PMI type I also has a C-terminal beta-barrel fold which has diverged considerably from the N-terminal domain and is not included here. This subfamily does not contain an alpha helical domain that exists in eukaryotic and some prokaryotic PMIs. F6P is a substrate for glycolysis and gluconeogenesis, while M6P is a substrate for production of activated mannose donor guanosine 5'-diphosphate D-mannose, an important precursor of mannosylated biomolecules such as glycoproteins, bacterial exopolysaccharides and fungal cell wall components. PMI is also essential for survival, virulence and possibly pathogenicity of some bacteria and protozoan parasites, as well as for cell wall integrity of certain yeasts. Thus, PMI is a potential target against fungal infections causing serious illness or death.	1.35641e-68
NZ_CP011271.1\|WP_082842037.1\|7159487_7160267_-\|hypothetical-protein	gnl\|CDD\|259883	cd04221, MauL, Methylamine utilization protein MauL. MauL is one of the products from the methylamine utilization gene cluster in Methylobacterium extorquens AM1. Mutants generated by insertions in mauL were not able to grow on methylamine or any other primary amine as carbon sources. MauL belongs to the blue or type I copper protein family. They are involved in electron transfer reactions with the Cu center transitioning between the oxidized Cu(II) form and the reduced Cu(I) form.	4.76243e-05
NZ_CP011271.1\|WP_082842038.1\|7160300_7161923_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	5.02352e-25
NZ_CP011271.1\|WP_082842041.1\|7171644_7172823_-\|AAA-family-ATPase	gnl\|CDD\|336785	pfam07728, AAA_5, AAA domain (dynein-related subfamily). This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.	2.59869e-40
NZ_CP011271.1\|WP_157470492.1\|7158386_7159481_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	3.28499e-110

>NZ_CP011271.1|WP_052556633.1|7163384_7163690_+|hypothetical-protein
MIRKLVLGAVAATAIGFGTQTATAGEPFRGPVGPSNGGFVPPHQRHDHDYVVFVKRGGHFGYWERYGRYETRREAERVERFLESRGHRARIEVVEDRRRPW
>NZ_CP011271.1|WP_082843447.1|7162138_7163134_-|hypothetical-protein
MARPPLYPLRFEPIFTTNLWGGRRLPAFLNRTVTHTDPIGEAWILSDVDGSPSRVVDGPLAGSTLREVFSADPCRIVGGAKAPQGRFPLLLKFLDARQELSVQVHPNDSQAALLGPGKFGKTEAWVVLERDPVTSRLFAGFAEGVRANDFRAALATKTAPRTLHSFTPNTGDCVFLEAGTVHAIGSNLLLFEVQQTSDITYRLYDWDRVDAKTGQPRQLHINEALACADFGRGPCYPVGPSVVVSNGVRREGLVTCAHFTLERLTSAVPFRVGAKNQCRAVVCVNGHGELESAGVRYPIRTGDVYLLPAEVGTAIVVPATEVTLLECGLPV
>NZ_CP011271.1|WP_082842038.1|7160300_7161923_-|sigma-70-family-RNA-polymerase-sigma-factor
MSARLRLPSLLPALDDRALLSRFTEQHDQPAFEQLVKRHGQLVFGVCRRTVRDTHLAEDAFQAVFLVLARNPRGAAEAISVGGWLFGVARRIGLAARRQEQRREKREQKATTEERIEEAPRADFNDVLRVLDEELAAIPDESRAALVACFLEERTHDEAARELGWSLSTLRRRLDRGKELLRSRLARRGVTLAVGLLTGALASPARAATLTPVPSPTSVALATEALKRGIGTKLWATTVGAVLAVSGIAFGVAYEPNNPLVPPSDPVAERSEAPKTQLDAAPAPHAVAKPWVTVSGRIVFPKERVIPDPRLVPTNGIQDAEVWKSFAPLRYEDTIINDKNRGIANVVVWLRPDSDDRKASFSREKIRPLLVDPEAQEHHVVAVAGQFLPRTLAVRAGDRVTFTNRLKVPTNIRYTAAISDMASTMREFNVLVTNDTSRTSEPVPTLQMPDSFRSTVHPWMTGFVWAFDHPYFAVTDASGRFTIENAPAGKWRLVAWHEVPGFLGGAPGRFGEKITISESRAGTLELDPREFESRVWSAKK
>NZ_CP011271.1|WP_082842037.1|7159487_7160267_-|hypothetical-protein
MRLLLSCVCCCALVSVASAQQQWVTVKGQVVFPANKPIPKPAALKVDVDKKECLAKGAVLDESILVNPKNRGIKNVVVYLRPNNPNLKADFAANQIHPADAKRKPEEVVIDQPCCAFVKRVTVARVGDTIVVKNPAPIAHNFFWDTANNGTHNPTIAKQTDWTMPNPLVKETTPIQYKCTIHPWMAGYVRIFDHPYYAITDEDGKFEIKNAPVGNFQIVYWHENGVRGGAKGRAGEAIQIAGAGATMEMKPTDFDVSPK
>NZ_CP011271.1|WP_157470492.1|7158386_7159481_+|aminotransferase-class-V-fold-PLP-dependent-enzyme
MVLSPSPLGGGVGEGLQPEPPPPSPLPKGKGEKELSVDAAPSTEKMRASSPFPDRRGLQGEPAGGSPSPGARGDGGVGCVSSRLEHPCVVEPLRHLESLGVSVEWLPANTRGVIESGAITAQAGALVCVMLANHETGAIQPVREIALVLPKGARLHCDAVQAVGKMPVNFRELGATTLTASAHKFGGPKGVGVLLAKRGTSLTPLTYGGHQQQGRRPGTEPVALAVGMAVALELATRNMAANRAKLESHRARLWTTLERTCPPAVLNGPEIGAPDVVPTTLNVSFPGCRSDLLLMSLDLAGVACATGSACSSGSLLPSPVLRAMGVSDEVLKSALRFSFSPAQTSEEIDDAAARIAKCVSATRA
>NZ_CP011271.1|WP_082842035.1|7157221_7157929_-|DNA-alkylation-repair-protein
MTANEVMAQLKKLGSEQTKKTLMKHGAKEPFFGVKVADLKVLQKKIKTDHALALELYDTGNSDAMYLAGLVADPEAVTKAQLQKWVKGAYWYMLSGFTVPWVASESPFGRELALDWIDSDAEQIANAGWSTYGCVLSIKPDAELDLPEIEKLLKRITAEIGSATNRVRYAMNAFVISVGGYVAPLTAKAKAAAKVIGAVEVDMGDTSCKVPDATAYIAKIEQMGRVGKKRKHAAC
>NZ_CP011271.1|WP_082842034.1|7156272_7157166_+|hypothetical-protein
MRTASALAALVVLAAPLAAADPVNLKWSLKDGDKFYASTSQELNQTIKVMGQTVDQKMTTTTVARFDVKSAKTGALEIQMTYTQVQIKMNGPLAAAGAGANALTDRFKGATLTATFDKNFEITKLDGYDKFLDKLSDGDEMMRKVFETMMPENAVRLTFSQVIVPAPSDKVSTGHKWSRTDKVPLPGLGDLTNKTQFTLDGVKNDIATIKTTADVTFKAAGGGGALPFKITKADLKSDEVKGTILFDTKGGRLKSSDATMKLKGSMTIEVQNMEIEAELDQKMVTKTEILEKNPVKD
>NZ_CP011271.1|WP_052556624.1|7155140_7156121_-|Gfo/Idh/MocA-family-oxidoreductase
MPVTKDTIGVGFIGAGDISVLHAAAVKKCPGAKLVGLWNRNQQRATQRATEFGCKNYATPEELVADPEIDAVFVLTNLETHLEYTALALGMGKHVLVEKPVGMSVAEIERMKALADAKDLICMPGHNYVYESGMVRTRELVDGGDLGKVVSAYVMYNIHHPEDVASRYPGVVRQILTHHSYILLYLVGKPVELCAMKATLHYKEYKEEDIAMVQMRLQNGALAHFCASFAADDHAADPWTVMVKVIGTAGSTRYSYRDHVEIKPGLVHSQTYTAYQGSITNEVRHFLIDCLRMGQKPLSTLDDAITAQKLIEAAEKSIAEKSVVTL
>NZ_CP011271.1|WP_082842033.1|7154078_7155011_-|hypothetical-protein
MEYRPLGKTGLNVSVLGQGGAAFGQQYGAVSDREVMDCVHAAIDAGVNLIDTAAYYGKGTSEEFLGRALEGGRREKVVVCTKACRLDRAVFDFTPEGTRKCVEGSLKRLRTDHVEILLAHDIEFATDYEYVFNETYAVLQQLKKEGKARFIGMSCYPLPLLKQAIERCDLDVVISYAHGNLFNTQLLSDFMPVAEARGVGVMNASPLAMGLLTNQGPQSWFPGPPEVIETCRKAAELCRSRGADISFLGMQFALALKQIPCTLSGAARKSELEVNLKALTAPVDEALLTDVMKVLDPIRNRTWKCGNWPG
>NZ_CP011271.1|WP_052556620.1|7152773_7153841_+|DUF1559-domain-containing-protein
MPTDDDDLPRKRPWDNDRHDDEADRPRRRRPGDDEDDHDERPRRRPRAEDVDDYDDDRPRRRPRGDDDDDRPRRSAPQSNGLAIAGLILSVLGFCTCGLAAVPGIICSAIAMSKPVGRGLAVAGLVVGLLGVLVGGSIGVGLMLPAVQKVREAAARQKNSNNMKQIGLALLNQESANGTMSAPYATDNRGQVNRDLSWRVGVLPYIEQDSVYRQFDLSQAWNSPQNQRPANMVIGTYSSPLSAEPGSTKTPYRVFYGGGAMFNEDGKPVRITDVTDGISNTIMAVHAVEEVPWAQPRELLYNPNAPLPQLWANNRPVTQVLMADGSVRMVKKTVSEQTLRNAITRSDGQRLGADW
>NZ_CP011271.1|WP_082842039.1|7165426_7166641_-|amidohydrolase-family-protein
MSERTESRTFTARWVFPVSGTPLPNGTVTVRGERIEAVLPHGARTPDEDLGNAAIIPGLVNPHTHLDLSGARGLIPPTDADHFTDWLRGVIDYRRTRTPEQTQSDIRAGLTECLRHGTTLIGDIASEGASWDALAGAPTRAVVFREFIGLGLERAAAAVTAAEAATKSLAQTPNCRMGFSPHAPYSVRQTLLEQVTELARFHHLPVAVHLSESPGEIELLQRHSGPFRTFLQDLGIWHADALSESPDAWITRQFRCAPDLYIHANYLASTLRIPENGSVVYCPRTHAAFGHAPHPFREFLARDVRVCLGTDSLASNPDLDVLSEARFVRTRYPDFPGDQLLRMVTLSGAEALGWADETGSLEADKSADLVVVPLPNTDISDPHELVLADHAGDRRTMFRGAWRT
>NZ_CP011271.1|WP_052556637.1|7167106_7167391_-|GIY-YIG-nuclease-family-protein
MPQAKKSRWVVYILRCADGTLYTGITTDLERRLGQHNAGTASKYTRARRPVAVAYRTTVKTHGDALRRELAIKKLTRTAKDALIAKQVKRRKRA
>NZ_CP011271.1|WP_157469967.1|7167491_7167653_+|hypothetical-protein
MLRRPSTHLPTHLGERCSSTAFAAANNFATADWINLAGRGSAVAKLFAAAAMP
>NZ_CP011271.1|WP_052556639.1|7167745_7168906_-|VWA-domain-containing-protein
MSDPHTLARWRLVLGRTAEQHGINCGGNGEAERIEELVGFLFEPGAGDGSGSHGRGGRGGGRRSSGRAGGSGGPQLTVPDWVDQVNELFPNQSKEVMQKELVKRRGISELMEKPELLEKIEPNMELVKTLLTHRDLLNEKTRILARKIIEQVVEELRRKMQVQVEQAITGAIRKDRHSPRKVYRNLDLKTTLRRNLKNYDPDTGKLLVDRVFFYAAERKKKPWHVIVVVDQSGSMLESAIFSAVMASIFAELPAVKTSLVLFDTEVVDLSDQVGQPVDVLLSIQLGGGTDITKGLMYANELVRQPGRTIVVLITDFYEGRDEKDLVDQTRLMADSGVRMIGLGALGYDARPSYNKPTAQKLTKVGMDVLVCTPEKLAECMAQIIRG
>NZ_CP011271.1|WP_082842040.1|7169061_7171482_-|hypothetical-protein
MSAQLTDAGLDATEIAKRVDAVLTDPLYWFPVRHHSPTTARHVQAAIAARKPKVVFIEGPFEANDLIPHVVDAATAPPVAIYSSYRDDDNVLGLNGYASAAPDIPARFAVWYPLTPYSPEYVAMKTAATIKADVVFIDLPHYARVERHAPTPEGRQPPREAPVVAPNEDRLITSSGFYKHLADAAGFKSWDEAWDTLFENPVADDYEAYRREMATFCCAARATADHAAEHAEDTVERERHFLKTIRETLAARKLKPEDAMVVCGGFHLFLDRADKAAPPECPAGTVYTTVVPYSYFRISEMSGYGAGNRAPQFYQTCYDLVAAGRASDIAMEHAIAVLRHMRKGGDPLSTADAISVTHHAGMLARLRGRPHPTLDDISDALITCCCKGNPNEEGTKLRAAMDVAGIGTKIGKVTSKLGRLPIVNDFHTQISDLELGEVLGKEKKMSVKLDKRDALAARRSAFLHRVSYLKVPFAGIVNTGGDFSGTLFREDWHLKWDPKTEPALIEQNLYGDTVEAAALNRLREAMAQAGTNAGQTCARLLEAVDMDMPDLVQAAEDACGDAIDTDASFPSLATALRHLGRLEQYAVFRGLRRSVLEDLLTRCYDRACFALPDAANAPEEEQQGVVDGLISVAEVVLRDPVRYDRVLFAQAARTAAANSTVPFLRGAFLGLLCEIRELPATALAAEVASLALASVEVMVTAGDLLDGMLAVSQTSLMLGAERLVAAVDDLLKAAEWDPFLVMLPRLRAAIERLSNPQKDSLAATVARHYGLAGSEDLRAMSGSLGATALVARLDAAVAATLKDWPL
>NZ_CP011271.1|WP_082842041.1|7171644_7172823_-|AAA-family-ATPase
MAKKPAAPAAPSAATSSGSVSPETVLREPAEKRYADQLEALRQNDTEAPPTNWKLSPRSVLTYVIGGKTLKATIGGKSVEVPITRKFFGDDGVVERSIVTLASERALLLVGEPGTGKSWLSEHLAAAICGTSLLTIQGTAGTTEEHIKYSWNIARVIAEGPTAQNMIASPAMIAMKGGALLRFEELTRCVPDVQDALVSILSDKAVAVPELPGDAMVFAKPGFNIIATANTRDQGVNELSAALKRRFNYVYIPIVGDQKTEVKIVQQRSAELLERYNLPAKLSPPVIELLATVFREIRNGKTSDGVSIKKPSTTLSTAEAIGVALDAALHARFFGGGEVGPADIARNMVGAVVKEDQEDKVALKEYATVVAKKRGAKDKSWKEFHDALVEQL
>NZ_CP011271.1|WP_082842042.1|7172900_7174022_-|hypothetical-protein
MLPPTADRPKLRATLDQLSAAVEDLLLGGLTTASDATRQTLSGAMQEAARLRLLRLGGTLRVATEELGRFTRQEKSFSRRRLTFFLNRAWLLSRGMGHALDTSDEKEYDRLTWSPPAQPLPAVKVVCLGAVKKVAEHAFVAFEFRLRAIADAGAVKAGQKLSWSAVFPLKKGQDIPPEGFLHLPQKQKFAPFLFLERTTLNIANATVSGDETSGWRLALTDQSTVTVGKPFTGWDQFLAWSPQSALDRLAKHVPGPLDLDTELQEEVVLRDYEVGKAEDGDEPGQTVYPITMGALTLHALIGAGAEGKALKKSIDEIRKVRGANPPLFGLMHYERCRLVFQPLTTFPGSSDYITISKENVNKAALLKAMDFRS
>NZ_CP011271.1|WP_082842043.1|7174025_7174373_-|hypothetical-protein
MDEIAELRDALDRLHAAMDDLVVRGVRAAGPTDIAKLTALRDEFRTAGAEHLAEKLSTLVDAVQAGERAAAPALMRAVTTFRLFDRMLTLEVARGALSPPVAVPRDDEAEPEGDE
>NZ_CP011271.1|WP_082842044.1|7174504_7176907_-|hypothetical-protein
MAKQGTNTRTAGALAGQTVAFVGKFAHDINHYKDVWVKNAGGTVGPPTGTFDYLVYGEGRGGKVPGAVARIEKRRPGLTVLDLTEFAKIVLPTAAEFVARVKRLEPTPEYWNSFQALCRTAGLPVDLSKIDLRGTHMEGAKLGGALLNGVDFRSVNCSQAVLSTTHTIEGAKFDGAKLVRATLNKAKKCSFRDADLKQAWAAQASYEACDFRDAIMSEIRIGRSQFTDGDFRGADLSDAESEGTTFERCDFSKANLTRFRGHGAQLTDAKLVGANLNRADLRETSLRGADLRNADLRDAALAGADLTGVNVAGADFTGAGLTGANVQGVDFSKAKNFAPPVARAAGPNLKALVKAASSAKDFETTVDVDLGKNEHAKMSLRVGQLGIRATANHYRGGTEIQSTIAAPTFQQGLLNLADRWPKATLRLDTIRAHGSRNVRGTKLRTMAIAAWAEAFGMDLSNGIPLTEQQKAQEAEARRKRDELVEQIRDKGPSVWHAIDFRERQRYNLRGLDLRDGRLMGLDMARREDLRDSRFAGANLSGSKLWGSDLHGADFTNANLAGAELQFSKCEKTSFVNANLRNANLNNTRLFGTDFTGAHLDGARFENAQFDERTLFPVGFKTPENLVWKGEGPRPGPRRPPQAVSGSMDFDTFFKGLPKKVKPERVEKATSMLKSESYQLYADLTDANLVGIVKSQSNKDLVYSCRLASDGQFYCGTQNLRACGGLHGALCKHLLVLVIGLAKSDKLDPATADNWVSASKDHQPVIDRDAVSETFLKFKGAEAGEIDWRPTETVPEDFYAM
>NZ_CP011271.1|WP_082842045.1|7176919_7177444_-|hypothetical-protein
MAKTKATQPKIPAARTEWDDFLDGARGVSDSAKLAKALTMLRGEKFQLYADVQPEFVCGVVRSQSSGSRVYACRLANDGKYSCCTQNLIQCVVSRGSPCKHLLVLVVGLVKAGHLAPATALEWLRGARKKGLTADGYKPDKDVVTATFLKYKGMEAGEIDWRPTDTIPEDFYSA

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Crispr_ID: NZ_CP011271_25

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_25

7198794-7198904

Orphan

Consensus_repeat	Method
GTATCTCCGTGGGGCAACTCACGGCCGAATTGAAGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_25

>merge|NZ_CP011271|25|7198794-7198904|CRISPRCasFinder
GTATCTCCGCGGTGCAAGCCGCGGCCGAATTGAAGCATGATCGAGCCGGACAAGTCGCGGTTCCAGATGGTTGGGGTATCTCCGCGGCGCGAGTCGCGGCCGAATTGAAGT

>NZ_CP011271|25|25|7198794-7198904|CRISPRCasFinder
GTATCTCCGCGGTGCAAGCCGCGGCCGAATTGAAGC	ATGATCGAGCCGGACAAGTCGCGGTTCCAGATGGTTGGG
GTATCTCCGCGGCGCGAGTCGCGGCCGAATTGAAGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_082842065.1\|7196071_7197088_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842059.1\|7191616_7192795_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842075.1\|7204972_7210621_-\|phage-portal-protein	unknown	unknown	gnl\|CDD\|239645
NZ_CP011271.1\|WP_082842077.1\|7212130_7212541_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_162271888.1\|7200765_7201992_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP011271.1\|WP_082842073.1\|7203315_7203801_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_157469970.1\|7199561_7199771_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842070.1\|7199829_7200132_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842072.1\|7202047_7203247_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842064.1\|7195621_7195960_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842067.1\|7197553_7197919_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238045
NZ_CP011271.1\|WP_082842061.1\|7194235_7194754_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842066.1\|7197084_7197366_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842068.1\|7199230_7199491_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223442
NZ_CP011271.1\|WP_082842060.1\|7192794_7194045_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842076.1\|7211744_7212062_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_157469968.1\|7198155_7198332_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842062.1\|7194795_7195194_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842063.1\|7195190_7195625_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842074.1\|7203857_7204847_-\|hypothetical-protein	unknown	unknown	unknown

>NZ_CP011271.1|WP_157469968.1|7198155_7198332_+|hypothetical-protein
MLTSFTETVNAAHPGPHAVICDGVLLFQYPTYLEAADRACDLESVGCTAVVVPVDLHN
>NZ_CP011271.1|WP_082842067.1|7197553_7197919_-|helix-turn-helix-domain-containing-protein
MMTQEQLAALVGISYQSLARYERGAVEPTWPKVLQLAKALDVSPEAFTTAEDQPAPLEPIAETDVMHAMPATVSPVQHVDLEITINRKFDSYTEEDQRKLMEAIARLLEIDGIKVTSRKKG
>NZ_CP011271.1|WP_082842066.1|7197084_7197366_-|hypothetical-protein
MPETPAADTERLTLEVVDAKGKVLRTVEGVEATRVEKKDGAIGFVLKTTTLKGERPEAGWRLVDANKDTWTIKRAARGGQGESWSASCEKKKP
>NZ_CP011271.1|WP_082842065.1|7196071_7197088_+|hypothetical-protein
MPAIEPPDAATIATWEIRERGVRDGGSPVETFEGSSSHAERTFFCKWEHRGEVVKWMLGHAIVWDDSGTLKLSRLPAQVHPNFPGLICTKCTSIRGHRWIDNAVPIDPDPDIGYEFSAAQINEFENAELVFQYESMPFPNLPDDDEQVIVNGEVARYCSTDQYDVSGEYLQLPGAAFVWQRGTAAAPNGQSIPMNVGKIMPSAVVSVTWWRLPDEVWAPGSALWQRVFGSDEGDDPFLGKINSAEMFGMPQGCVLFSGIKPVRRRSPLGDGFEWDVTFEFSFKPSGWNWVYFMDPTTHTNSGFYFVGKPGSGVQPADVLDDGVSIYNSIDLNDLFKVS
>NZ_CP011271.1|WP_082842064.1|7195621_7195960_-|hypothetical-protein
MELSAADLVADFDLFDGRGTATIHQRDPVSGDVTATETATVLRRQTSAQAVSIGDGELAATTCRFHLKATDLSFAPKKRDRIIYCEVTWDVEQVTVAGMGTRYMCDVIQVRE
>NZ_CP011271.1|WP_082842063.1|7195190_7195625_-|hypothetical-protein
MSRAGQIADAVVAGVNALALPGAPAATRLKTPSLPPGTEPSQIVVTMSNVPRSEFVTNDSYIDRYAGAVTIITAGGDVLGDDETVRAWAEAIRAKLQRWETFASMATFNDCLVEDLEFFPRPALDKTLNYTTQKFTVEVKESRS
>NZ_CP011271.1|WP_082842062.1|7194795_7195194_-|hypothetical-protein
MSVSGKYLTAKIGAAEIKGTYAWRVSERYEKLDAITAADNGNNRKDFGVGEAEISLRLLIDIASGAYEPVAAGTEITALTLYRKKGDAQPAYSFPLVRIFDSEQGAEIRGRVEVNATGENVGIYARNEPAAP
>NZ_CP011271.1|WP_082842061.1|7194235_7194754_-|hypothetical-protein
MNQSLADLLNSPGDFPFEGVTYKLGQPTVMQMGQYARWLEQRAREATVRATDLDDDTRRVLLKDVIADIAAGVYEWGSETCCKAMQLPRGQAKFLAIMLADQGVDDETADRMIASRLADVVSLIQIAVSDDPKAMAAALNQLGLPSNFVSSGSPIRRSTGRSKKSKRSRSRK
>NZ_CP011271.1|WP_082842060.1|7192794_7194045_-|hypothetical-protein
MNFDGRVLVTALGLVAKSLVDLNGNVVLLARTFGGAPAGAAGAQGTTQPTTAPQQQQHTKPNSMSPGAPSGGGPNSNSAAYNFGSALRTLLQQVMKARSQAGGKRSGGGRREKSLLGRMFSRKTFNHFRKAARTAFRGGRGKGKGFLGAIGIGKRGGGIAQGARGAGAILGYIARLISMPFEKIIGLLNPMAVMAQAINSSASGFQVFGSAVKVLAATFAPLLLPLFANFAAGVIEMSDDLWNELLPVLEDFYDICQTVLIPAVQLMVDAFLFAVQAIKSATEIVADLTSGDSDRILNRLNPFSSEEEDEEAMMKRLGQGDFSGDRGSGGGANPWRDRARNDVFRELRQSMGAKASFSQIAQAGKNVQLAALNTSPFEARILERMDKAIGAMERVERNTQPKPVSRARPADDGGTF
>NZ_CP011271.1|WP_082842059.1|7191616_7192795_-|hypothetical-protein
MPPRSRPPRPFVSPDIGVATVRGADTLGSIDFGADWFPCRVTGTVTGGYSFVETMVNASGAVVDKPYGRKNSATDPAVPIDGATLAVGDKVQCRRAPGSANQRWELGPKAGTPVPIWKDPAYCCTTAALPANTYANGSGGVGATLTANSNGALPNQDSQAPFLGMRIIVGYEVSNRNGLYVVTSLGSASTRWVLTRAADCDSPAEVDGAVCQALFGLTHIGIWELKNLNAAYPTTVGFHSLGWLPVTGRNVGVQWGTSGAITPDSTWIATPYSVTLPHRGWWLVTCHIRTECTIATGATYPGIVRVRLYNTSINAQVGGMMQGAMSQVPNMTGYAGTTICQLVATTIPCTVRIEVMREYNANWLSAQWTTNGDNGSTPINQQVMNCVCVGPF
>NZ_CP011271.1|WP_082842068.1|7199230_7199491_-|hypothetical-protein
MSKQRPLDIEDDDRPRPHSRPALPPPGAVAAGFFNLAKWFALGAAAMLAAVAITQGAVWASAFAGLACFVAIVARILQAEEHIRRR
>NZ_CP011271.1|WP_157469970.1|7199561_7199771_-|hypothetical-protein
MDIATELRTVLENFVTALKLASAAPKPTYSIDGQSVSWGEYLKMLQEGIKATSELLGTFDPVEVRTSII
>NZ_CP011271.1|WP_082842070.1|7199829_7200132_-|hypothetical-protein
MPRVTDIREAVAGAGAPLAEPEEKPAVTEEKPGRATKPKPAPTEDENDEAGPLKKYRVELTHLPAREVEAFDRLDAIERYKTQMGVISTPHNFTVQRSKS
>NZ_CP011271.1|WP_162271888.1|7200765_7201992_+|helix-turn-helix-transcriptional-regulator
MPRKRIDPTFGLRLKEIRNTAGFTQAKLGELTGLLPNAIARLEGGKREPGWETVQKLAEALGVATDAFKAVKSQPQPSQPVPVQSHATQIEYSSSLPAPEHFNQVANDAAAWLPIYHHWNKLSKSPFHLALDGGGFRSHLYFEVPRYPSVNKLALTSLARPVEVSVVLGAMPTFHVHVSSRGDVRFTKPVRQRIHLTDGGFGRLFPGQVHVTDAEAGKMFIPTDALDHIASPRINIFGGVPRIEMWVDTDNAGEDAGSGSEKTDEPLFSTAATGTNRTKRYTYDANNRLATATPPLDAASELTYPLRVASGDVDGDSTPPLNTRRVEGRIFANVAGNSVKYEYDAAGNLMTREYNTTGICTSRKNKTIVIVLNCSVGDASAEEVTRLLAEIKKTCNYELVDIVSISPR
>NZ_CP011271.1|WP_082842072.1|7202047_7203247_-|hypothetical-protein
MARIGLKLREVMAGKPAREGAKLATDVLREGIKSGRISRDDISLREMAHSLIGDDWESHLRNYTGRLREAVDAVDSSGFSPITGQLLVDEIKEKYKLATFVTDKMFRTIKVTNGNLGTQVVPYLTDTIDDPGIVQQGQNYPATQFNGQYITLPAPEKFGRICRVTFEMIYSDLTRQVMDSASSVGKRVGLWVEKKRLRVALGLDNNHVWNGTAFNTYLTAGSWVNALTDFTLVDWTSINRLEQLFANMLDPVLNEPIEIDGAQMLVLPALKYTAKRVLNATEVLSGNITSGAGNQIVSANPLDGNYELMSSKHARRQLRTYGAGTFTTDPIADSLVLFGSFKEAFAWREVFAPQFVQAPPQAPAEFEQDVVLQAKANVYGVACVTEPRKVIRAYNSSAT
>NZ_CP011271.1|WP_082842073.1|7203315_7203801_-|hypothetical-protein
MPVPQYIEGETRPRKVAIATAKLVDKGDLVGMNAGTLVRAEDETWTTDLATTQSNFRARFAGVAAQSKLSTTNPRVFGNSQDNVIMVNTSGVFEFDCASATFEVGDFVGPAKDTGNALLSDRVVAVGAEANAIGRVAERGTAITRVKVETLSVLAPAARQS
>NZ_CP011271.1|WP_082842074.1|7203857_7204847_-|hypothetical-protein
MEITLRESLTVGSIGRVDRAANTIRDVRVCGLRSTNGRRYSAGALRNAKQLYEGARAFFNHPDGESNTRKFGDRIGRLVNVREADDGGLIADLKYNPKHRDAEAFLWLAEHDPAGMGLSHNAEGRGVRQGDGEILVEEITKVHSVDIVDNPATNLSLFEQDTSMDPVVDPAAGASGSGGGDVNDKLAALAADFAKHPEWDKKTKITKLKALINLMEDGDADAKGADDEMSEGEMMEQLGAFRSPAVRRARAQLLVESRRRLASEKGLAGDLVTGVFLEQLAAVPEATALKLIEDRRGVATVAKATAPKSTQQVVAVEKTAAEIAAEINW
>NZ_CP011271.1|WP_082842075.1|7204972_7210621_-|phage-portal-protein
MAAYNEFAICALENRVNYVVGEGLKYTATGKDPRNAAHRKSAECVQHVIEVWESLNNLPEMEAEALWRLDVEGEFFIRRFPDKKGFDHLRFVEPELVRAPIASTTDPAMSFGIETDAEDVVSVRAYWIVDAPTQDMAPTRVVADDVIHAKLNTWSSAKRGVPTFYPVEANLKRCEDLLASMTSVAKARAKIALIRKITGLTSSTADTLLARLTAARATDPNTGETLNIEQLRYGTVLTASGNTDYQMPAANLGAGDIVEVLQAELRAVASRMVMPEWMFTALADAKFNNAFIVEAPTTKSFKRLQKRMRDAFGRIAHGPRVSLLWRQLRAAVAAGLLCANDLENVVIGCIGPTLEARDPQGEVTRHKEMVEAGFESKETAQRSLELDPEKEAPQIAREMAGRARPTADASAVAQTQEAFYAGKLPRDAAAANLMILLGFTREQAEALLPASDCVKRTDDGPQPGGMPGTPGAPAIPGDTPPDSGGDVPVGDGSQPAPQAPEHGADDGVMDAITREAMQALGVDTPEPVQEQFREAHAEGEVFQAGQRWYVVKNGHVQPAPAPTSSVGAKSGARSTGKPVAPAAPQTPPTPTDAKAANTVWAKVPEAKKNTAAAKIATAAKAAKDKELLAKAAVWADKMAAKHADAVAKKLNVSPTLARYLLANAIKSLCAKAVKTGGAATMDLDTSGSLGGGKIKLGVKVKPREAFDPNEARDAAGQWTADGGTLTSDPADYEQTVHIGGWGGAKVRPAKRPDGSWGWKRQGKGYSPTEQLTAEQKDSKGYFTEDGWFYLDRDQTPGARWKAGYAPKLASVHPLIRAALEPDAHGIDWRPTSAVPEDFYIEQTAAAPSGALVLREAGFTGVVTATNGVTYHYVDGKRVAAAAHEDHVTKGGQPSPVIKAPDANQFADIIHLVGDHYVKGEADWKAAGKAIDKVLKKYGGGQAEWDKLAAQFGFDTGGKKSVGALLNAIKSHFDAHGVDESKVVAAKGEAAAEPAPQSAPESAPQATSEAAPQVTPEETVNELKTYLNSTVLSPAEAKDAIHHALYDAIVAGHDGAALMAQALGVPSIDTSNLNALLDSHFANKATATESPETAEPDAPESPEQAAEPETPAAPNADAPELGSRDGYKPATFDPAAAPVKDYTGKSPQEIDPTWKVNPNPAKQAYGGVLVRTDPATGKTQVLLRKPTGNFDGYVWTWPKGKLTDAQKTHPDAQTAALAEVAEETGHKGEIIDHVPGVFKSDGSTTNAFFLMKSAGEDPSLMDKETAETQWVDIDKAHELIEQTTKAAGKKRDLEILEAAKAKLGSADDPKINAAADDLKAAVHALAEQGASPEQVAATFKQKLSGFHPHAVAAIASKTITSGDPADLIPKAVDFVTEHKGLPVLANIKNVKPIGKGSTGAKIGTTASGAKVVIKDGGGKPHGQEQVGNEVAADKIYQLLGANIAKSKVETKDGVKHKVAQWVEGESLNTYLNNATPEQAGAVKKEIQKQFVATALLGNWDVAGQTLDNIKVSPDGKPYLIDNGGSFDISANATKKGGTQKPFAADSVPELATLLDSAKAPQAASVFAGISKDEIVSQINDVVAKKDAILTATPTAHKAAMAKRIEYLATWAAKDGKPNAVKVDGGAHGDIWLNPKPGVHVHRNHLAKDIGSPETVDYINHIDPHEYQAIRKYTGNSYAALNSALYAKKPLDAHSQEVDDGLQGTFAKAATFPPKTLVRMMNSPGPKFLDVLQRAMASDRPIKWRNYQSAGPGGTFGKHRNMKITFENVTEGAIDVEPLTSVPGEHELLLNRGTFYKVKSVTENKGKVHVVMTQIPKTVAETGHYLEAAAPVSDGPAVTGTPGDPPAQKDPDREWTAEELAARAKQKDDEFAAQFVANMTAHHG
>NZ_CP011271.1|WP_082842076.1|7211744_7212062_-|hypothetical-protein
MSDVSELDRELRRAVAAEAKLREATIDVVQSLGSWTSRDLAFAASDAMGVAGCGIYSPPLYQDNTKSGEVIPVYKTEGELFSAYPGVTQFILEEPGAVAEDRCSP
>NZ_CP011271.1|WP_082842077.1|7212130_7212541_-|hypothetical-protein
MSASLVANPPIKIPRGQDTTIRVKTFPATDISSWGAVLLTIRADPNYPRASLVDVTAARTGDLDTKSWSVALTSTAYTVVDAAKGIFDIAIPRAAALALEAGTQRYVLDVWRTDPGSEWQVVEPTWVSMLPSIRDN

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Crispr_ID: NZ_CP011271_24

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_24

7198507-7198686

Orphan

Consensus_repeat	Method
GTATCTCCGTGGGGCAACTCACGGCCGAATTGAAGC	PILER-CR
GTATCTCCGTGGGGCAACTCACGGCCGAATTGAAGC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP011271_24

>merge|NZ_CP011271|24|7198507-7198686|PILER-CR,CRISPRCasFinder
GTATCTCCGTGGGGCAACTCACGGCCGAATTGAAGCCCGTTTGAAGGCACCGTTTACAAGCTCGGTCAGCCGGTATCTCCGTGGGGCAACTCACGGCCGAATTGAAGCCGGTCTTCGCATCGACCACTTCGAGGGTCAGTTTCGTATCTCCGTGGGGCAACTCACGGCCGAATTGAAGCG

>NZ_CP011271|24|4|7198507-7198685|PILER-CR
GTATCTCCGTGGGGCAACTCACGGCCGAATTGAAGC	CCGTTTGAAGGCACCGTTTACAAGCTCGGTCAGCCG
GTATCTCCGTGGGGCAACTCACGGCCGAATTGAAGC	CGGTCTTCGCATCGACCACTTCGAGGGTCAGTTTC
GTATCTCCGTGGGGCAACTCACGGCCGAATTGAAGC

>NZ_CP011271|24|24|7198507-7198686|CRISPRCasFinder
GTATCTCCGTGGGGCAACTCACGGCCGAATTGAAGC	CCGTTTGAAGGCACCGTTTACAAGCTCGGTCAGCCG
GTATCTCCGTGGGGCAACTCACGGCCGAATTGAAGC	CGGTCTTCGCATCGACCACTTCGAGGGTCAGTTTC
GTATCTCCGTGGGGCAACTCACGGCCGAATTGAAGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_082842065.1\|7196071_7197088_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842059.1\|7191616_7192795_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842075.1\|7204972_7210621_-\|phage-portal-protein	unknown	unknown	gnl\|CDD\|239645
NZ_CP011271.1\|WP_082842077.1\|7212130_7212541_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_162271888.1\|7200765_7201992_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP011271.1\|WP_082842073.1\|7203315_7203801_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_157469970.1\|7199561_7199771_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842070.1\|7199829_7200132_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842072.1\|7202047_7203247_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842064.1\|7195621_7195960_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842067.1\|7197553_7197919_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238045
NZ_CP011271.1\|WP_082842061.1\|7194235_7194754_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842066.1\|7197084_7197366_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842068.1\|7199230_7199491_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223442
NZ_CP011271.1\|WP_082842060.1\|7192794_7194045_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842076.1\|7211744_7212062_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_157469968.1\|7198155_7198332_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842062.1\|7194795_7195194_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842063.1\|7195190_7195625_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082842074.1\|7203857_7204847_-\|hypothetical-protein	unknown	unknown	unknown

>NZ_CP011271.1|WP_157469968.1|7198155_7198332_+|hypothetical-protein
MLTSFTETVNAAHPGPHAVICDGVLLFQYPTYLEAADRACDLESVGCTAVVVPVDLHN
>NZ_CP011271.1|WP_082842067.1|7197553_7197919_-|helix-turn-helix-domain-containing-protein
MMTQEQLAALVGISYQSLARYERGAVEPTWPKVLQLAKALDVSPEAFTTAEDQPAPLEPIAETDVMHAMPATVSPVQHVDLEITINRKFDSYTEEDQRKLMEAIARLLEIDGIKVTSRKKG
>NZ_CP011271.1|WP_082842066.1|7197084_7197366_-|hypothetical-protein
MPETPAADTERLTLEVVDAKGKVLRTVEGVEATRVEKKDGAIGFVLKTTTLKGERPEAGWRLVDANKDTWTIKRAARGGQGESWSASCEKKKP
>NZ_CP011271.1|WP_082842065.1|7196071_7197088_+|hypothetical-protein
MPAIEPPDAATIATWEIRERGVRDGGSPVETFEGSSSHAERTFFCKWEHRGEVVKWMLGHAIVWDDSGTLKLSRLPAQVHPNFPGLICTKCTSIRGHRWIDNAVPIDPDPDIGYEFSAAQINEFENAELVFQYESMPFPNLPDDDEQVIVNGEVARYCSTDQYDVSGEYLQLPGAAFVWQRGTAAAPNGQSIPMNVGKIMPSAVVSVTWWRLPDEVWAPGSALWQRVFGSDEGDDPFLGKINSAEMFGMPQGCVLFSGIKPVRRRSPLGDGFEWDVTFEFSFKPSGWNWVYFMDPTTHTNSGFYFVGKPGSGVQPADVLDDGVSIYNSIDLNDLFKVS
>NZ_CP011271.1|WP_082842064.1|7195621_7195960_-|hypothetical-protein
MELSAADLVADFDLFDGRGTATIHQRDPVSGDVTATETATVLRRQTSAQAVSIGDGELAATTCRFHLKATDLSFAPKKRDRIIYCEVTWDVEQVTVAGMGTRYMCDVIQVRE
>NZ_CP011271.1|WP_082842063.1|7195190_7195625_-|hypothetical-protein
MSRAGQIADAVVAGVNALALPGAPAATRLKTPSLPPGTEPSQIVVTMSNVPRSEFVTNDSYIDRYAGAVTIITAGGDVLGDDETVRAWAEAIRAKLQRWETFASMATFNDCLVEDLEFFPRPALDKTLNYTTQKFTVEVKESRS
>NZ_CP011271.1|WP_082842062.1|7194795_7195194_-|hypothetical-protein
MSVSGKYLTAKIGAAEIKGTYAWRVSERYEKLDAITAADNGNNRKDFGVGEAEISLRLLIDIASGAYEPVAAGTEITALTLYRKKGDAQPAYSFPLVRIFDSEQGAEIRGRVEVNATGENVGIYARNEPAAP
>NZ_CP011271.1|WP_082842061.1|7194235_7194754_-|hypothetical-protein
MNQSLADLLNSPGDFPFEGVTYKLGQPTVMQMGQYARWLEQRAREATVRATDLDDDTRRVLLKDVIADIAAGVYEWGSETCCKAMQLPRGQAKFLAIMLADQGVDDETADRMIASRLADVVSLIQIAVSDDPKAMAAALNQLGLPSNFVSSGSPIRRSTGRSKKSKRSRSRK
>NZ_CP011271.1|WP_082842060.1|7192794_7194045_-|hypothetical-protein
MNFDGRVLVTALGLVAKSLVDLNGNVVLLARTFGGAPAGAAGAQGTTQPTTAPQQQQHTKPNSMSPGAPSGGGPNSNSAAYNFGSALRTLLQQVMKARSQAGGKRSGGGRREKSLLGRMFSRKTFNHFRKAARTAFRGGRGKGKGFLGAIGIGKRGGGIAQGARGAGAILGYIARLISMPFEKIIGLLNPMAVMAQAINSSASGFQVFGSAVKVLAATFAPLLLPLFANFAAGVIEMSDDLWNELLPVLEDFYDICQTVLIPAVQLMVDAFLFAVQAIKSATEIVADLTSGDSDRILNRLNPFSSEEEDEEAMMKRLGQGDFSGDRGSGGGANPWRDRARNDVFRELRQSMGAKASFSQIAQAGKNVQLAALNTSPFEARILERMDKAIGAMERVERNTQPKPVSRARPADDGGTF
>NZ_CP011271.1|WP_082842059.1|7191616_7192795_-|hypothetical-protein
MPPRSRPPRPFVSPDIGVATVRGADTLGSIDFGADWFPCRVTGTVTGGYSFVETMVNASGAVVDKPYGRKNSATDPAVPIDGATLAVGDKVQCRRAPGSANQRWELGPKAGTPVPIWKDPAYCCTTAALPANTYANGSGGVGATLTANSNGALPNQDSQAPFLGMRIIVGYEVSNRNGLYVVTSLGSASTRWVLTRAADCDSPAEVDGAVCQALFGLTHIGIWELKNLNAAYPTTVGFHSLGWLPVTGRNVGVQWGTSGAITPDSTWIATPYSVTLPHRGWWLVTCHIRTECTIATGATYPGIVRVRLYNTSINAQVGGMMQGAMSQVPNMTGYAGTTICQLVATTIPCTVRIEVMREYNANWLSAQWTTNGDNGSTPINQQVMNCVCVGPF
>NZ_CP011271.1|WP_082842068.1|7199230_7199491_-|hypothetical-protein
MSKQRPLDIEDDDRPRPHSRPALPPPGAVAAGFFNLAKWFALGAAAMLAAVAITQGAVWASAFAGLACFVAIVARILQAEEHIRRR
>NZ_CP011271.1|WP_157469970.1|7199561_7199771_-|hypothetical-protein
MDIATELRTVLENFVTALKLASAAPKPTYSIDGQSVSWGEYLKMLQEGIKATSELLGTFDPVEVRTSII
>NZ_CP011271.1|WP_082842070.1|7199829_7200132_-|hypothetical-protein
MPRVTDIREAVAGAGAPLAEPEEKPAVTEEKPGRATKPKPAPTEDENDEAGPLKKYRVELTHLPAREVEAFDRLDAIERYKTQMGVISTPHNFTVQRSKS
>NZ_CP011271.1|WP_162271888.1|7200765_7201992_+|helix-turn-helix-transcriptional-regulator
MPRKRIDPTFGLRLKEIRNTAGFTQAKLGELTGLLPNAIARLEGGKREPGWETVQKLAEALGVATDAFKAVKSQPQPSQPVPVQSHATQIEYSSSLPAPEHFNQVANDAAAWLPIYHHWNKLSKSPFHLALDGGGFRSHLYFEVPRYPSVNKLALTSLARPVEVSVVLGAMPTFHVHVSSRGDVRFTKPVRQRIHLTDGGFGRLFPGQVHVTDAEAGKMFIPTDALDHIASPRINIFGGVPRIEMWVDTDNAGEDAGSGSEKTDEPLFSTAATGTNRTKRYTYDANNRLATATPPLDAASELTYPLRVASGDVDGDSTPPLNTRRVEGRIFANVAGNSVKYEYDAAGNLMTREYNTTGICTSRKNKTIVIVLNCSVGDASAEEVTRLLAEIKKTCNYELVDIVSISPR
>NZ_CP011271.1|WP_082842072.1|7202047_7203247_-|hypothetical-protein
MARIGLKLREVMAGKPAREGAKLATDVLREGIKSGRISRDDISLREMAHSLIGDDWESHLRNYTGRLREAVDAVDSSGFSPITGQLLVDEIKEKYKLATFVTDKMFRTIKVTNGNLGTQVVPYLTDTIDDPGIVQQGQNYPATQFNGQYITLPAPEKFGRICRVTFEMIYSDLTRQVMDSASSVGKRVGLWVEKKRLRVALGLDNNHVWNGTAFNTYLTAGSWVNALTDFTLVDWTSINRLEQLFANMLDPVLNEPIEIDGAQMLVLPALKYTAKRVLNATEVLSGNITSGAGNQIVSANPLDGNYELMSSKHARRQLRTYGAGTFTTDPIADSLVLFGSFKEAFAWREVFAPQFVQAPPQAPAEFEQDVVLQAKANVYGVACVTEPRKVIRAYNSSAT
>NZ_CP011271.1|WP_082842073.1|7203315_7203801_-|hypothetical-protein
MPVPQYIEGETRPRKVAIATAKLVDKGDLVGMNAGTLVRAEDETWTTDLATTQSNFRARFAGVAAQSKLSTTNPRVFGNSQDNVIMVNTSGVFEFDCASATFEVGDFVGPAKDTGNALLSDRVVAVGAEANAIGRVAERGTAITRVKVETLSVLAPAARQS
>NZ_CP011271.1|WP_082842074.1|7203857_7204847_-|hypothetical-protein
MEITLRESLTVGSIGRVDRAANTIRDVRVCGLRSTNGRRYSAGALRNAKQLYEGARAFFNHPDGESNTRKFGDRIGRLVNVREADDGGLIADLKYNPKHRDAEAFLWLAEHDPAGMGLSHNAEGRGVRQGDGEILVEEITKVHSVDIVDNPATNLSLFEQDTSMDPVVDPAAGASGSGGGDVNDKLAALAADFAKHPEWDKKTKITKLKALINLMEDGDADAKGADDEMSEGEMMEQLGAFRSPAVRRARAQLLVESRRRLASEKGLAGDLVTGVFLEQLAAVPEATALKLIEDRRGVATVAKATAPKSTQQVVAVEKTAAEIAAEINW
>NZ_CP011271.1|WP_082842075.1|7204972_7210621_-|phage-portal-protein
MAAYNEFAICALENRVNYVVGEGLKYTATGKDPRNAAHRKSAECVQHVIEVWESLNNLPEMEAEALWRLDVEGEFFIRRFPDKKGFDHLRFVEPELVRAPIASTTDPAMSFGIETDAEDVVSVRAYWIVDAPTQDMAPTRVVADDVIHAKLNTWSSAKRGVPTFYPVEANLKRCEDLLASMTSVAKARAKIALIRKITGLTSSTADTLLARLTAARATDPNTGETLNIEQLRYGTVLTASGNTDYQMPAANLGAGDIVEVLQAELRAVASRMVMPEWMFTALADAKFNNAFIVEAPTTKSFKRLQKRMRDAFGRIAHGPRVSLLWRQLRAAVAAGLLCANDLENVVIGCIGPTLEARDPQGEVTRHKEMVEAGFESKETAQRSLELDPEKEAPQIAREMAGRARPTADASAVAQTQEAFYAGKLPRDAAAANLMILLGFTREQAEALLPASDCVKRTDDGPQPGGMPGTPGAPAIPGDTPPDSGGDVPVGDGSQPAPQAPEHGADDGVMDAITREAMQALGVDTPEPVQEQFREAHAEGEVFQAGQRWYVVKNGHVQPAPAPTSSVGAKSGARSTGKPVAPAAPQTPPTPTDAKAANTVWAKVPEAKKNTAAAKIATAAKAAKDKELLAKAAVWADKMAAKHADAVAKKLNVSPTLARYLLANAIKSLCAKAVKTGGAATMDLDTSGSLGGGKIKLGVKVKPREAFDPNEARDAAGQWTADGGTLTSDPADYEQTVHIGGWGGAKVRPAKRPDGSWGWKRQGKGYSPTEQLTAEQKDSKGYFTEDGWFYLDRDQTPGARWKAGYAPKLASVHPLIRAALEPDAHGIDWRPTSAVPEDFYIEQTAAAPSGALVLREAGFTGVVTATNGVTYHYVDGKRVAAAAHEDHVTKGGQPSPVIKAPDANQFADIIHLVGDHYVKGEADWKAAGKAIDKVLKKYGGGQAEWDKLAAQFGFDTGGKKSVGALLNAIKSHFDAHGVDESKVVAAKGEAAAEPAPQSAPESAPQATSEAAPQVTPEETVNELKTYLNSTVLSPAEAKDAIHHALYDAIVAGHDGAALMAQALGVPSIDTSNLNALLDSHFANKATATESPETAEPDAPESPEQAAEPETPAAPNADAPELGSRDGYKPATFDPAAAPVKDYTGKSPQEIDPTWKVNPNPAKQAYGGVLVRTDPATGKTQVLLRKPTGNFDGYVWTWPKGKLTDAQKTHPDAQTAALAEVAEETGHKGEIIDHVPGVFKSDGSTTNAFFLMKSAGEDPSLMDKETAETQWVDIDKAHELIEQTTKAAGKKRDLEILEAAKAKLGSADDPKINAAADDLKAAVHALAEQGASPEQVAATFKQKLSGFHPHAVAAIASKTITSGDPADLIPKAVDFVTEHKGLPVLANIKNVKPIGKGSTGAKIGTTASGAKVVIKDGGGKPHGQEQVGNEVAADKIYQLLGANIAKSKVETKDGVKHKVAQWVEGESLNTYLNNATPEQAGAVKKEIQKQFVATALLGNWDVAGQTLDNIKVSPDGKPYLIDNGGSFDISANATKKGGTQKPFAADSVPELATLLDSAKAPQAASVFAGISKDEIVSQINDVVAKKDAILTATPTAHKAAMAKRIEYLATWAAKDGKPNAVKVDGGAHGDIWLNPKPGVHVHRNHLAKDIGSPETVDYINHIDPHEYQAIRKYTGNSYAALNSALYAKKPLDAHSQEVDDGLQGTFAKAATFPPKTLVRMMNSPGPKFLDVLQRAMASDRPIKWRNYQSAGPGGTFGKHRNMKITFENVTEGAIDVEPLTSVPGEHELLLNRGTFYKVKSVTENKGKVHVVMTQIPKTVAETGHYLEAAAPVSDGPAVTGTPGDPPAQKDPDREWTAEELAARAKQKDDEFAAQFVANMTAHHG
>NZ_CP011271.1|WP_082842076.1|7211744_7212062_-|hypothetical-protein
MSDVSELDRELRRAVAAEAKLREATIDVVQSLGSWTSRDLAFAASDAMGVAGCGIYSPPLYQDNTKSGEVIPVYKTEGELFSAYPGVTQFILEEPGAVAEDRCSP
>NZ_CP011271.1|WP_082842077.1|7212130_7212541_-|hypothetical-protein
MSASLVANPPIKIPRGQDTTIRVKTFPATDISSWGAVLLTIRADPNYPRASLVDVTAARTGDLDTKSWSVALTSTAYTVVDAAKGIFDIAIPRAAALALEAGTQRYVLDVWRTDPGSEWQVVEPTWVSMLPSIRDN

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Crispr_ID: NZ_CP011271_27

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_27

8927388-8927519

Orphan

Consensus_repeat	Method
ACCATGCGGCAGGTGGTGTAGCACACCTGCCGAACG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_27

>merge|NZ_CP011271|27|8927388-8927519|CRISPRCasFinder
ACCATGCGGCAGGTGGTGTAGCACACCTGCCGAACGTGTTGCTCCGGCACGGTGTAGCAGCGGTACCGGGTTTCGGTGCGGGTGTGTTGTTCCGGAACCATGCGGCAGGTGGTGTAGCACACCTGGCGAACG

>NZ_CP011271|27|27|8927388-8927519|CRISPRCasFinder
ACCATGCGGCAGGTGGTGTAGCACACCTGCCGAACG	TGTTGCTCCGGCACGGTGTAGCAGCGGTACCGGGTTTCGGTGCGGGTGTGTTGTTCCGGA
ACCATGCGGCAGGTGGTGTAGCACACCTGGCGAACG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_082843131.1\|8917717_8918407_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237865
NZ_CP011271.1\|WP_082843144.1\|8933537_8934143_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP011271.1\|WP_082843146.1\|8936713_8938831_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238901
NZ_CP011271.1\|WP_082843517.1\|8930658_8930901_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082843149.1\|8941423_8941834_-\|response-regulator	unknown	unknown	gnl\|CDD\|381085
NZ_CP011271.1\|WP_052549526.1\|8923832_8924600_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082843136.1\|8921139_8921406_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082843147.1\|8939866_8940313_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052549516.1\|8931028_8931589_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|379658
NZ_CP011271.1\|WP_082843133.1\|8919266_8919464_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082843143.1\|8931723_8933631_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236766
NZ_CP011271.1\|WP_082843140.1\|8925832_8926672_-\|menaquinone-biosynthesis-protein	unknown	unknown	gnl\|CDD\|270352
NZ_CP011271.1\|WP_082843138.1\|8923069_8923798_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213233
NZ_CP011271.1\|WP_082843132.1\|8918547_8919267_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237864
NZ_CP011271.1\|WP_082843142.1\|8929251_8930106_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082843137.1\|8921489_8922980_+\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NZ_CP011271.1\|WP_082843148.1\|8940402_8941365_+\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|187553
NZ_CP011271.1\|WP_082843145.1\|8934251_8936027_+\|PQQ-binding-like-beta-propeller-repeat-protein	unknown	unknown	gnl\|CDD\|379140
NZ_CP011271.1\|WP_082843134.1\|8919559_8920549_-\|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH	unknown	unknown	gnl\|CDD\|234597
NZ_CP011271.1\|WP_082843135.1\|8920579_8921149_-\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_082843131.1\|8917717_8918407_+\|hypothetical-protein	gnl\|CDD\|237865	PRK14951, PRK14951, DNA polymerase III subunits gamma and tau; Provisional.	1.55306e-11
NZ_CP011271.1\|WP_082843144.1\|8933537_8934143_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.48094e-18
NZ_CP011271.1\|WP_082843146.1\|8936713_8938831_-\|hypothetical-protein	gnl\|CDD\|238901	cd01920, cyclophilin_EcCYP_like, cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these have reduced affinity for cyclosporin A. E. coli cyclophilin A has a similar peptidylprolyl cis- trans isomerase activity to the human cyclophilin A. Most members of this subfamily contain a phenylalanine residue at the position equivalent to Human cyclophilin W121, where a tyrptophan has been shown to be important for cyclophilin binding.	5.16633e-34
NZ_CP011271.1\|WP_082843149.1\|8941423_8941834_-\|response-regulator	gnl\|CDD\|381085	cd00156, REC, phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response regulators (PRRs). Two-component systems (TCSs) involving a sensor and a response regulator are used by bacteria to adapt to changing environments. Processes regulated by two-component systems in bacteria include sporulation, pathogenicity, virulence, chemotaxis, and membrane transport. Response regulators (RRs) share the common phosphoacceptor REC domain and different effector/output domains such as DNA, RNA, ligand-binding, protein-binding, or enzymatic domains. Response regulators regulate transcription, post-transcription or post-translation, or have functions such as methylesterases, adenylate or diguanylate cyclase, c-di-GMP-specific phosphodiesterases, histidine kinases, serine/threonine protein kinases, and protein phosphatases, depending on their output domains. The function of some output domains are still unknown. TCSs are found in all three domains of life - bacteria, archaea, and eukaryotes, however, the presence and abundance of particular RRs vary between the lineages. Archaea encode very few RRs with DNA-binding output domains; most are stand-alone REC domains. Among eukaryotes, TCSs are found primarily in protozoa, fungi, algae, and green plants. REC domains function as phosphorylation-mediated switches within RRs, but some also transfer phosphoryl groups in multistep phosphorelays.	4.23763e-29
NZ_CP011271.1\|WP_052549516.1\|8931028_8931589_+\|thioredoxin-family-protein	gnl\|CDD\|379658	pfam14595, Thioredoxin_9, Thioredoxin.	5.00873e-28
NZ_CP011271.1\|WP_082843143.1\|8931723_8933631_+\|hypothetical-protein	gnl\|CDD\|236766	PRK10811, rne, ribonuclease E; Reviewed.	6.18903e-07
NZ_CP011271.1\|WP_082843138.1\|8923069_8923798_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213233	cd03266, ABC_NatA_sodium_exporter, ATP-binding cassette domain of the Na+ transporter. NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.	5.72959e-104
NZ_CP011271.1\|WP_082843132.1\|8918547_8919267_+\|hypothetical-protein	gnl\|CDD\|237864	PRK14950, PRK14950, DNA polymerase III subunits gamma and tau; Provisional.	0.00207983
NZ_CP011271.1\|WP_082843140.1\|8925832_8926672_-\|menaquinone-biosynthesis-protein	gnl\|CDD\|270352	cd13634, PBP2_Sco4506, The conserved hypothetical protein SCO4506 exhibits the type 2 periplasmic-binidng protein fold. This group includes the SCO4506 protein from Streptomyces coelicolor and related hypothetical proteins. SCO4506 is an ortholog of Ttha1568 (MqnD) from Thermus thermophilies HB8. MqnD is an enzyme within an alternative menaquinone biosynthetic pathway that catalyzes the conversion of cyclic de-hypoxanthine futalosine to 1,4-dihydroxy-6-naphthoate. Menaquinone (MK; vitamin K) is an essential lipid-soluble carrier that shuttles electrons between membrane-bound protein complexes in the electron transport chain. SCO4506 has significant structural homology with the members of type 2 periplasmic-binding fold protein superfamily. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.45566e-96
NZ_CP011271.1\|WP_082843148.1\|8940402_8941365_+\|TIGR01777-family-protein	gnl\|CDD\|187553	cd05242, SDR_a8, atypical (a) SDRs, subgroup 8. This subgroup contains atypical SDRs of unknown function. Proteins in this subgroup have a glycine-rich NAD(P)-binding motif consensus that resembles that of the extended SDRs, (GXXGXXG or GGXGXXG), but lacks the characteristic active site residues of the SDRs. A Cys often replaces the usual Lys of the YXXXK active site motif, while the upstream Ser is generally present and Arg replaces the usual Asn. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.89068e-114
NZ_CP011271.1\|WP_082843145.1\|8934251_8936027_+\|PQQ-binding-like-beta-propeller-repeat-protein	gnl\|CDD\|379140	pfam13360, PQQ_2, PQQ-like domain. This domain contains several repeats of the PQQ repeat.	7.62413e-20
NZ_CP011271.1\|WP_082843134.1\|8919559_8920549_-\|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH	gnl\|CDD\|234597	PRK00050, PRK00050, 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH.	1.23529e-119
NZ_CP011271.1\|WP_082843135.1\|8920579_8921149_-\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	1.31604e-12
NZ_CP011271.1\|WP_082843137.1\|8921489_8922980_+\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	7.42197e-56

>NZ_CP011271.1|WP_082843140.1|8925832_8926672_-|menaquinone-biosynthesis-protein
MSTTLRVGAVNYLNTKPLIERLTDFAPGIELSLDLPSRLADQLAAGELDVGLIPVVEFFRGDNYTFVPNIAIGSRGPVLSVTLFSKVPWADIRTVALDEGSRTSAALTRIILEKRYGIEPVIQQLPIDTPADDLTTDAVLLIGDRAMRACLPGYRFAYDLGEEWTAWTGLPMVFAVWAIRSGVDLGEAERAFHQAKEYGLANAGLIAQREAPALGLDPGFCRRYMSNVLRYDLGPLELAGMQKYRELAEGVGVLANSGPAAGGGNTLQRRTPGLAAGVR
>NZ_CP011271.1|WP_052549526.1|8923832_8924600_-|hypothetical-protein
MTEETTLRLRLQTVAAYRELRRNVQKSGRENVIFALVMLGLAYFAHQNGQNTFVALIYVALGLGELLVGLFKWAVPSAEGLILDGMVLLVFAALNFGREFLRFQGGAQPTSTGIFFGLLMLYFAVGRFKNYAALRRLFAERPAPEHIAWFDDLVRDILTSDPHADQLALDLPTTPHWRVKLLGSTAFFVANNGGSVWVVGPDDFVLVREKHDRGGGRRKALLRIYGDAYPEFTLDDVSWANYARWMDEFAAPHPA
>NZ_CP011271.1|WP_082843138.1|8923069_8923798_-|ATP-binding-cassette-domain-containing-protein
MIEVRDLSKWFRGPNGQRVTAVDAVRFTVHPGEVFGLLGPNGAGKTTTLRMLCTVLRPSDGTATVAGHDVVTDPGEVRRHVGFLSANTGVYDRMTAWELVEYYGRLHQVPPEELYPRMEELFTTLQMTNFRDTRGGKLSTGMKQKLSIARALVNDPPVLIFDEPTAGLDVLVQRAVLDSIKRLRGRGKTIIFSTHIMREVEKLCDRVAVMAKGRVIVCGTLNELREMYKQDDLEELFFDLVS
>NZ_CP011271.1|WP_082843137.1|8921489_8922980_+|serine-hydrolase
MRWTFATAVLLAPFLSARGDEPKPEAADAVMTDALKAFQVPGAALVVVRGDQTLVLKGYGYRSIDAKDPVTPDTSFPLASCTKQFTTALLAMLVDDGKLDWDDPVKKHLPDFKLSDPNASALLTVRDLVTHRTGLASHDLLWYRAPWSIDHILKQVPLLPLEYPFRSGYRYNSITFMAAGRIAERCGKEKWEKLVRERLIDPLEMKGVTFTTTEIAKDADRALGHQLNKTGKIERAPIYEMKEPNPSGSMNATARDLVSWLQFHVSDGVAPSGQRLVSSKPLLETRTPQNLMRLEGAAKFPFPDTVQLSYAMGWVVNDYRGLKVVAHGGLIDGFRIQITLVPEKDLGFAVLTNLHDTRMPIAATNTLVDLYCDLKPKDWNAHFRKLVDDEAEAKKAALAARDMARDPNAKPSLPLTALAGEYTNPAYGTATVRFADGKLTATFGAFTYPLEHYERDTFRVTGGRFETELATFTVTDKKVKGLTLSGIEFKTVPPAR
>NZ_CP011271.1|WP_082843136.1|8921139_8921406_-|hypothetical-protein
MNRRVTIIGAGLLVLVVAGLVIPFIVKARLKANLAASQNNLRELALFAAHNAKPDPNNDKRKLLTEIPAGTIALYGTPPKSGSVGSWG
>NZ_CP011271.1|WP_082843135.1|8920579_8921149_-|DUF1559-domain-containing-protein
MGVIPGMDQRRVNSEQLLSTIDRTKPWNADTNQQAARTRLPVLLCPENLPEIPPGSPAITCYVGISGLGANAAALPIDSPQAGAMRYDAPTPFERISDGLSQTLLFAETRNELGPWLRGGPSTVRGLDNAPGVPALIGTDGQFGGYFPGIAHFAMCDGSVRAFTANADPRVLYGLSTIAGKNTDPVPGE
>NZ_CP011271.1|WP_082843134.1|8919559_8920549_-|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH
MSDEPPKKKKKRPFWRKRIRRSTTEGEHKPVLLAEVLAALNPQPGQTIVDCTLGFAGHSLELLQRVSPDGLLISTDLDAGNIEPARAKLEAAGGLFALHHSNFAGLPTVLAMEGMSQVDGVLADLGMSSMQVDDRTRGFSFMRDGPLDMRMDRTRGRTAADLLATLSKDELAACFSEFGDEPQAETIAAAIVTQREVKPVERTKELRELIDRAAPVRVDRSPGAPPERRQLLGPATRVFQALRILANRELANLQQLLRVLPTILKPGGVAAIISFHSGEDRLVKAAFRDGLRSGVYEAVSPDAIRSTFDERRANPRSRSAKLRVAKMKA
>NZ_CP011271.1|WP_082843133.1|8919266_8919464_+|hypothetical-protein
MNLPLLAVSIYWDLPVLLVVVSLVYAATRHDRWDKIIHEATGWGLRITLFLAGIGTVLYLLSTYI
>NZ_CP011271.1|WP_082843132.1|8918547_8919267_+|hypothetical-protein
MASSPTNDPPLPPVTLDPIAGLLSYIIPGLGQIYQGRVGKGLLFFGGLYLLFFYGMWMGQWRNVWLPDTEDLPAVAFAGTDLPGAAKAISYRPQFLGQFWIGAAAWPGVYQYIAFDKAKDEGPIFGKFQRMPDEKELNDLQRNGNKRWDLGWVYTVIAGVLNLLVIYDAFAGPMFRDPPSEWIGDEHEEAYTAAPRAPAPAAPLPPPVTTVPSFKPPAPPVEAPAHTAPPVPPTAQGGA
>NZ_CP011271.1|WP_082843131.1|8917717_8918407_+|hypothetical-protein
MATAPSPNDLTRQQLDELDALLQKMLMVPLAPAEVPVPPPSMTQPPLPPSWRVDAPATVPAPSLAHLAVNEPPATLKFEPPAPATPAPVAKAPAPVPTPAAPPQPAPVPVPAPAPAPMVKVTPAPTKTPTPKPTPAPQPKAPPPPAPPTALTPVPAAPPVPFVFLPFVALNGLFDSICGMFGPLGRLFRSGFFKNLLGFAGLGLIVYTVLHVAQVQGWVSLPVMLPWPK
>NZ_CP011271.1|WP_082843142.1|8929251_8930106_+|hypothetical-protein
MSTATILDREEYIEQAYLYRTVRERIADNQPAQDVFLRVGEELLSSTRLPFAVQFVASELKHTGLVANGFAKLPHYFTAFQAFVVRQAENEKSRLPMPTAFLILEREAAYRAEKPTKAGLFVYQFETIARNRLGYLDGLEALALDPFYDTNWRGYFDHLRKQVGEIDFCDLVYLRSDLYVIEERRRNPTFEPPLPPIFGEKEGKIAKASRTRDPLYLFAALQRQLGYPEVPRYRVRDDATTKLELIQTKLRELELRIKLAESELRGSVDLSQFGKPELLKDDDE
>NZ_CP011271.1|WP_082843517.1|8930658_8930901_+|hypothetical-protein
MREVVGNPFRPVAFSHSWRTSTAVALASQMYEARDFSAMPILADALQDAGCDSADVLNHCRGPGPHVRGCWVVDLVLGKE
>NZ_CP011271.1|WP_052549516.1|8931028_8931589_+|thioredoxin-family-protein
MNLFSKFEAGLPLAEFLAKYGTDAHRARWQSATAQTTLTDDQQKLLRAFTRRTNVLVLAGAWCGDCSSQCPIFERIAEAAPVVVTRYLDRDEHADVQAALQINGGNRVPVAVFFSEDGHEVARYGERTLARYRQLVSQLTGEGCATGFVKGTDPVQQAAVQEWLDQFERVQWILRLSPRLRRLHGD
>NZ_CP011271.1|WP_082843143.1|8931723_8933631_+|hypothetical-protein
MIRYRCPHCAALTVAHERRIGQSSVCKACLKPHQIPADPTLWLSETGELLNPPAAAIPVDVRPTSISEIELPAVPFEIAETNVEPVAVVDTPPPLRIHENEITETEVESVVESATPAPVAEEPSEPFVQAPEAALELTRDADPIEEPSEPFVSAPEVHVPEPIRVNVEREPEVTRTEPLAPTPIVFAPEPITPEPIAPRVTHPIEREPWTEPVAAQKPEPESVSAVATATIPSQLVRDLPVPAPTPAPRVPERTPPPVAREATPVPPRVTIAEPVQLQTQVDITVALTAALSSRMRPPPAPRRDLRPSTAAWMLLTGAGVACVLVALFGDADLRWAALAIGATQILIGYVWIVRMTHARDPQRGLLCAIPPVTLFYLTQHKYARLRPLRFVLTGAVLAGLSAAVPALANLTQPLLAKKTPPPPPEPVAESKLAQLRTFRDQRDYKSLIKLLEILTKTDPIRSADAKDRDELATELKSLCQHQFIDVRTGALAALFRWDADPNAAVTRELCLAALRAPTQEERVNALELLPRWKDAESARAAQSLIGRSSEETHMAKTVLKNIGGPPAEQAALALLKRSEDQATRLTAIDILETVGGTESVGELRAYATATNDTVVRTRALGATTAIEERMRKPAP
>NZ_CP011271.1|WP_082843144.1|8933537_8934143_-|MarR-family-transcriptional-regulator
MSSETAPSPDGALRLAHAFANFGPAYFKWVQSQFAACGVSFARMRLLAVLHKLGPQIMSSLSDELGVTARNVTALVDALAGDGLVRRVPHATDRRATVVELTEAGARHGCMMADGSHLEMIAALFRDLTEEEQGQMLSIVTKLQGLLARRGFTNGPGGRPRPKARARDDWLYGAGLRMRSSIAVVAPRARVRTTVSFVAVA
>NZ_CP011271.1|WP_082843145.1|8934251_8936027_+|PQQ-binding-like-beta-propeller-repeat-protein
MTESTLLSPDPAPAPSRWRRALVVATIFGAGAYGFGWLAGRDDSGTIPSQAMMMSVMLGPILALLGFALWWVARGDGRFRRRVLGVVAVGASVGVSVLVAHSTMRLFAAIWGVPLTAAITGLALAAVPVVRSWPTAGLIALTALSPWLALRLDGVSGKFDMDTSYRWVPSVAERAAEQLASRATVVPTGPIAELIPESPLDWPGFRGAHRDGVVAAVAAHGWNGSAPRERWRKEPVGPAWSSFSAAGAFIYTQEQRGDSESVVCYQADTGDEVWARGEPGKHSDGPSGIGPRATPTCANGRVFAATASGTIMCLRATDGEPVWVVSLAERFGVTKPTFGYAASPLVTGNRVFINPSSKTGPRLVALDAATGATQWEVETRGTEGYSSPHPATIAGVSQVLIFNGAGLFGHDPETGRELWKYDWVTAQNEPTTVQPLALADGRIVIGGGNVGIGTRCVKVENSGSNWSASEVWKTSRFTPKFNDVVRVGKYLYGLDSGALVCLKLADGSRAWKEGQYGAGQVLLVGDNLLVVSETGQLACVAAKPDEFEELWKIDAVKGKTWNHPIIARGRLYLRNATVMVAFDLPGWSANP
>NZ_CP011271.1|WP_082843146.1|8936713_8938831_-|hypothetical-protein
MSSRRNPPLNSRRFVPRVEGLEDRTVPSGNVQIAVAGGTLFVAGDDQGNKIWIAGNGREGATVRALDATTTINGQTGPISLGGIRNDLYVRMYGGDDQLLVTGIRNRGALDVDMGAGNDTLGVSDAGQRGATVLRAGDGNDNVILNGSIFRKYLFLDTGAGDDSVTASRIGVINFGLMNPSGNDFFDRQNSTITRPVTVGTVTAGARPSVTDTDGPTVLITTTLTSPATANPLTYTVTFDEDVTGFDEADLIVTNGTVASVTARDARTYTVQVTPTSAGVVTVTVDANGAVDAAGNGNLASNTVVLTFNSSTDTTAPAAPTFDLAAASDSGTVGDLRTDASSVTLTGRAEAGATVRLYQTTVPGTPGAGSPMAEVTAAVDGTFSFTNVALNIGPNSFTVRAVDSAGNSGSTFTQTFTRNTAPTVASAITNQNLAVGAQDLVFNLTNTFVDAERVVRMMTTYPNGQTGVIDINLFANLAPATVANFLSYNYDGTIFHRLESNFVLQTGGFTFNDSGTTTATAFPPITASAPVVNEPGISNTRGTVAMAKVGGNPNSATNQFFFNLGDNSTNLDTQNGGFTVFGQVMHGGQQVVDAISGLPVFRSLDAPGAGSEPSPFPVRSGADTSNFPANINASDIATVTTVRELAAVDRMAFGATSSATGVATVSVTNGQLTVHAVASGTTTITVTATDLDGSVTQTQFTVTVP
>NZ_CP011271.1|WP_082843147.1|8939866_8940313_+|hypothetical-protein
MSTPVPDLPPIKEYKSQQYEFNDEHNREISALADAMRVTSGLMLLVGLAFVVLAALTITHTANSGGNYGPAVGLGTAALLCLCIGFWTGGAATSFRKIVETKNEDIWHLMNALGSLRSMYGLLRALIYGALVLTMIGLGLVGFALMGK
>NZ_CP011271.1|WP_082843148.1|8940402_8941365_+|TIGR01777-family-protein
MKIVLPGGSGQVGTILARHFHATGHEVVVLGRKPAPTAWRSVAWDAQTLGPWANELDGADVVVNLVGRSVNCRYTPANRREIIESRVRSVQLLGEALARSNRPPRVWLQSSTATIYAHRFDAPNDETTGIIGGNEPNAPDTWTFSIDVATSWEKALDAVHAPHTRKIAMRSAITLSPDREGVFDVLLGLVRRWLGGRSGDGKQFVSWVHEHDFIAAVEFLIQNDAMHGPVNIAAPEPLTNAEFMRVLREAWGVRFGLPAAKWMVELGAWALRTESELVLKSRRVVPGKLLEAGFKFRFPSWREAARDLCERWRQSASPVR
>NZ_CP011271.1|WP_082843149.1|8941423_8941834_-|response-regulator
MADQKLILVVDDDRELVDAMRAVLERQGYKVIQAHDGHQGKQAIYNARPDLVILDMMMPRMGGYPVLEHFKDKGDAPPIIMVTANEGSRHKVYAEYLGVIDYIRKPFAMERLLETVNKALGSGKPKEEKKEEKKAE

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Crispr_ID: NZ_CP011271_26

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011271_26

8927100-8927232

Orphan

Consensus_repeat	Method
ACCATGCGGCAGGTGGTGTAGCACACCTGCCGAACG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011271_26

>merge|NZ_CP011271|26|8927100-8927232|CRISPRCasFinder
ACCATGCGGCAGGTGGTCACGGGCACGTGCCGCACGCACACCTCGGGCACCTTCTCGACTACGCACCGCGTTTCGTACCGCACGTGGTCCTCTTTCACGAGCCGGCAGGTGGTGTAGCACACTTGCCGCGTTA

>NZ_CP011271|26|26|8927100-8927232|CRISPRCasFinder
ACCATGCGGCAGGTGGTCACGGGCACGTGCCGCACG	CACACCTCGGGCACCTTCTCGACTACGCACCGCGTTTCGTACCGCACGTGGTCCTCTTTC
ACGAGCCGGCAGGTGGTGTAGCACACTTGCCGCGTTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011271.1\|WP_082843131.1\|8917717_8918407_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237865
NZ_CP011271.1\|WP_082843144.1\|8933537_8934143_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP011271.1\|WP_082843146.1\|8936713_8938831_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238901
NZ_CP011271.1\|WP_082843517.1\|8930658_8930901_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082843149.1\|8941423_8941834_-\|response-regulator	unknown	unknown	gnl\|CDD\|381085
NZ_CP011271.1\|WP_052549526.1\|8923832_8924600_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082843136.1\|8921139_8921406_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082843147.1\|8939866_8940313_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_052549516.1\|8931028_8931589_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|379658
NZ_CP011271.1\|WP_082843133.1\|8919266_8919464_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082843143.1\|8931723_8933631_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236766
NZ_CP011271.1\|WP_082843140.1\|8925832_8926672_-\|menaquinone-biosynthesis-protein	unknown	unknown	gnl\|CDD\|270352
NZ_CP011271.1\|WP_082843138.1\|8923069_8923798_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213233
NZ_CP011271.1\|WP_082843132.1\|8918547_8919267_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237864
NZ_CP011271.1\|WP_082843142.1\|8929251_8930106_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011271.1\|WP_082843137.1\|8921489_8922980_+\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NZ_CP011271.1\|WP_082843148.1\|8940402_8941365_+\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|187553
NZ_CP011271.1\|WP_082843145.1\|8934251_8936027_+\|PQQ-binding-like-beta-propeller-repeat-protein	unknown	unknown	gnl\|CDD\|379140
NZ_CP011271.1\|WP_082843134.1\|8919559_8920549_-\|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH	unknown	unknown	gnl\|CDD\|234597
NZ_CP011271.1\|WP_082843135.1\|8920579_8921149_-\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919

Protein	Function_ID	Function_description	E-value
NZ_CP011271.1\|WP_082843131.1\|8917717_8918407_+\|hypothetical-protein	gnl\|CDD\|237865	PRK14951, PRK14951, DNA polymerase III subunits gamma and tau; Provisional.	1.55306e-11
NZ_CP011271.1\|WP_082843144.1\|8933537_8934143_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.48094e-18
NZ_CP011271.1\|WP_082843146.1\|8936713_8938831_-\|hypothetical-protein	gnl\|CDD\|238901	cd01920, cyclophilin_EcCYP_like, cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these have reduced affinity for cyclosporin A. E. coli cyclophilin A has a similar peptidylprolyl cis- trans isomerase activity to the human cyclophilin A. Most members of this subfamily contain a phenylalanine residue at the position equivalent to Human cyclophilin W121, where a tyrptophan has been shown to be important for cyclophilin binding.	5.16633e-34
NZ_CP011271.1\|WP_082843149.1\|8941423_8941834_-\|response-regulator	gnl\|CDD\|381085	cd00156, REC, phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response regulators (PRRs). Two-component systems (TCSs) involving a sensor and a response regulator are used by bacteria to adapt to changing environments. Processes regulated by two-component systems in bacteria include sporulation, pathogenicity, virulence, chemotaxis, and membrane transport. Response regulators (RRs) share the common phosphoacceptor REC domain and different effector/output domains such as DNA, RNA, ligand-binding, protein-binding, or enzymatic domains. Response regulators regulate transcription, post-transcription or post-translation, or have functions such as methylesterases, adenylate or diguanylate cyclase, c-di-GMP-specific phosphodiesterases, histidine kinases, serine/threonine protein kinases, and protein phosphatases, depending on their output domains. The function of some output domains are still unknown. TCSs are found in all three domains of life - bacteria, archaea, and eukaryotes, however, the presence and abundance of particular RRs vary between the lineages. Archaea encode very few RRs with DNA-binding output domains; most are stand-alone REC domains. Among eukaryotes, TCSs are found primarily in protozoa, fungi, algae, and green plants. REC domains function as phosphorylation-mediated switches within RRs, but some also transfer phosphoryl groups in multistep phosphorelays.	4.23763e-29
NZ_CP011271.1\|WP_052549516.1\|8931028_8931589_+\|thioredoxin-family-protein	gnl\|CDD\|379658	pfam14595, Thioredoxin_9, Thioredoxin.	5.00873e-28
NZ_CP011271.1\|WP_082843143.1\|8931723_8933631_+\|hypothetical-protein	gnl\|CDD\|236766	PRK10811, rne, ribonuclease E; Reviewed.	6.18903e-07
NZ_CP011271.1\|WP_082843138.1\|8923069_8923798_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213233	cd03266, ABC_NatA_sodium_exporter, ATP-binding cassette domain of the Na+ transporter. NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.	5.72959e-104
NZ_CP011271.1\|WP_082843132.1\|8918547_8919267_+\|hypothetical-protein	gnl\|CDD\|237864	PRK14950, PRK14950, DNA polymerase III subunits gamma and tau; Provisional.	0.00207983
NZ_CP011271.1\|WP_082843140.1\|8925832_8926672_-\|menaquinone-biosynthesis-protein	gnl\|CDD\|270352	cd13634, PBP2_Sco4506, The conserved hypothetical protein SCO4506 exhibits the type 2 periplasmic-binidng protein fold. This group includes the SCO4506 protein from Streptomyces coelicolor and related hypothetical proteins. SCO4506 is an ortholog of Ttha1568 (MqnD) from Thermus thermophilies HB8. MqnD is an enzyme within an alternative menaquinone biosynthetic pathway that catalyzes the conversion of cyclic de-hypoxanthine futalosine to 1,4-dihydroxy-6-naphthoate. Menaquinone (MK; vitamin K) is an essential lipid-soluble carrier that shuttles electrons between membrane-bound protein complexes in the electron transport chain. SCO4506 has significant structural homology with the members of type 2 periplasmic-binding fold protein superfamily. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.45566e-96
NZ_CP011271.1\|WP_082843148.1\|8940402_8941365_+\|TIGR01777-family-protein	gnl\|CDD\|187553	cd05242, SDR_a8, atypical (a) SDRs, subgroup 8. This subgroup contains atypical SDRs of unknown function. Proteins in this subgroup have a glycine-rich NAD(P)-binding motif consensus that resembles that of the extended SDRs, (GXXGXXG or GGXGXXG), but lacks the characteristic active site residues of the SDRs. A Cys often replaces the usual Lys of the YXXXK active site motif, while the upstream Ser is generally present and Arg replaces the usual Asn. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.89068e-114
NZ_CP011271.1\|WP_082843145.1\|8934251_8936027_+\|PQQ-binding-like-beta-propeller-repeat-protein	gnl\|CDD\|379140	pfam13360, PQQ_2, PQQ-like domain. This domain contains several repeats of the PQQ repeat.	7.62413e-20
NZ_CP011271.1\|WP_082843134.1\|8919559_8920549_-\|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH	gnl\|CDD\|234597	PRK00050, PRK00050, 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH.	1.23529e-119
NZ_CP011271.1\|WP_082843135.1\|8920579_8921149_-\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	1.31604e-12
NZ_CP011271.1\|WP_082843137.1\|8921489_8922980_+\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	7.42197e-56

>NZ_CP011271.1|WP_082843140.1|8925832_8926672_-|menaquinone-biosynthesis-protein
MSTTLRVGAVNYLNTKPLIERLTDFAPGIELSLDLPSRLADQLAAGELDVGLIPVVEFFRGDNYTFVPNIAIGSRGPVLSVTLFSKVPWADIRTVALDEGSRTSAALTRIILEKRYGIEPVIQQLPIDTPADDLTTDAVLLIGDRAMRACLPGYRFAYDLGEEWTAWTGLPMVFAVWAIRSGVDLGEAERAFHQAKEYGLANAGLIAQREAPALGLDPGFCRRYMSNVLRYDLGPLELAGMQKYRELAEGVGVLANSGPAAGGGNTLQRRTPGLAAGVR
>NZ_CP011271.1|WP_052549526.1|8923832_8924600_-|hypothetical-protein
MTEETTLRLRLQTVAAYRELRRNVQKSGRENVIFALVMLGLAYFAHQNGQNTFVALIYVALGLGELLVGLFKWAVPSAEGLILDGMVLLVFAALNFGREFLRFQGGAQPTSTGIFFGLLMLYFAVGRFKNYAALRRLFAERPAPEHIAWFDDLVRDILTSDPHADQLALDLPTTPHWRVKLLGSTAFFVANNGGSVWVVGPDDFVLVREKHDRGGGRRKALLRIYGDAYPEFTLDDVSWANYARWMDEFAAPHPA
>NZ_CP011271.1|WP_082843138.1|8923069_8923798_-|ATP-binding-cassette-domain-containing-protein
MIEVRDLSKWFRGPNGQRVTAVDAVRFTVHPGEVFGLLGPNGAGKTTTLRMLCTVLRPSDGTATVAGHDVVTDPGEVRRHVGFLSANTGVYDRMTAWELVEYYGRLHQVPPEELYPRMEELFTTLQMTNFRDTRGGKLSTGMKQKLSIARALVNDPPVLIFDEPTAGLDVLVQRAVLDSIKRLRGRGKTIIFSTHIMREVEKLCDRVAVMAKGRVIVCGTLNELREMYKQDDLEELFFDLVS
>NZ_CP011271.1|WP_082843137.1|8921489_8922980_+|serine-hydrolase
MRWTFATAVLLAPFLSARGDEPKPEAADAVMTDALKAFQVPGAALVVVRGDQTLVLKGYGYRSIDAKDPVTPDTSFPLASCTKQFTTALLAMLVDDGKLDWDDPVKKHLPDFKLSDPNASALLTVRDLVTHRTGLASHDLLWYRAPWSIDHILKQVPLLPLEYPFRSGYRYNSITFMAAGRIAERCGKEKWEKLVRERLIDPLEMKGVTFTTTEIAKDADRALGHQLNKTGKIERAPIYEMKEPNPSGSMNATARDLVSWLQFHVSDGVAPSGQRLVSSKPLLETRTPQNLMRLEGAAKFPFPDTVQLSYAMGWVVNDYRGLKVVAHGGLIDGFRIQITLVPEKDLGFAVLTNLHDTRMPIAATNTLVDLYCDLKPKDWNAHFRKLVDDEAEAKKAALAARDMARDPNAKPSLPLTALAGEYTNPAYGTATVRFADGKLTATFGAFTYPLEHYERDTFRVTGGRFETELATFTVTDKKVKGLTLSGIEFKTVPPAR
>NZ_CP011271.1|WP_082843136.1|8921139_8921406_-|hypothetical-protein
MNRRVTIIGAGLLVLVVAGLVIPFIVKARLKANLAASQNNLRELALFAAHNAKPDPNNDKRKLLTEIPAGTIALYGTPPKSGSVGSWG
>NZ_CP011271.1|WP_082843135.1|8920579_8921149_-|DUF1559-domain-containing-protein
MGVIPGMDQRRVNSEQLLSTIDRTKPWNADTNQQAARTRLPVLLCPENLPEIPPGSPAITCYVGISGLGANAAALPIDSPQAGAMRYDAPTPFERISDGLSQTLLFAETRNELGPWLRGGPSTVRGLDNAPGVPALIGTDGQFGGYFPGIAHFAMCDGSVRAFTANADPRVLYGLSTIAGKNTDPVPGE
>NZ_CP011271.1|WP_082843134.1|8919559_8920549_-|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH
MSDEPPKKKKKRPFWRKRIRRSTTEGEHKPVLLAEVLAALNPQPGQTIVDCTLGFAGHSLELLQRVSPDGLLISTDLDAGNIEPARAKLEAAGGLFALHHSNFAGLPTVLAMEGMSQVDGVLADLGMSSMQVDDRTRGFSFMRDGPLDMRMDRTRGRTAADLLATLSKDELAACFSEFGDEPQAETIAAAIVTQREVKPVERTKELRELIDRAAPVRVDRSPGAPPERRQLLGPATRVFQALRILANRELANLQQLLRVLPTILKPGGVAAIISFHSGEDRLVKAAFRDGLRSGVYEAVSPDAIRSTFDERRANPRSRSAKLRVAKMKA
>NZ_CP011271.1|WP_082843133.1|8919266_8919464_+|hypothetical-protein
MNLPLLAVSIYWDLPVLLVVVSLVYAATRHDRWDKIIHEATGWGLRITLFLAGIGTVLYLLSTYI
>NZ_CP011271.1|WP_082843132.1|8918547_8919267_+|hypothetical-protein
MASSPTNDPPLPPVTLDPIAGLLSYIIPGLGQIYQGRVGKGLLFFGGLYLLFFYGMWMGQWRNVWLPDTEDLPAVAFAGTDLPGAAKAISYRPQFLGQFWIGAAAWPGVYQYIAFDKAKDEGPIFGKFQRMPDEKELNDLQRNGNKRWDLGWVYTVIAGVLNLLVIYDAFAGPMFRDPPSEWIGDEHEEAYTAAPRAPAPAAPLPPPVTTVPSFKPPAPPVEAPAHTAPPVPPTAQGGA
>NZ_CP011271.1|WP_082843131.1|8917717_8918407_+|hypothetical-protein
MATAPSPNDLTRQQLDELDALLQKMLMVPLAPAEVPVPPPSMTQPPLPPSWRVDAPATVPAPSLAHLAVNEPPATLKFEPPAPATPAPVAKAPAPVPTPAAPPQPAPVPVPAPAPAPMVKVTPAPTKTPTPKPTPAPQPKAPPPPAPPTALTPVPAAPPVPFVFLPFVALNGLFDSICGMFGPLGRLFRSGFFKNLLGFAGLGLIVYTVLHVAQVQGWVSLPVMLPWPK
>NZ_CP011271.1|WP_082843142.1|8929251_8930106_+|hypothetical-protein
MSTATILDREEYIEQAYLYRTVRERIADNQPAQDVFLRVGEELLSSTRLPFAVQFVASELKHTGLVANGFAKLPHYFTAFQAFVVRQAENEKSRLPMPTAFLILEREAAYRAEKPTKAGLFVYQFETIARNRLGYLDGLEALALDPFYDTNWRGYFDHLRKQVGEIDFCDLVYLRSDLYVIEERRRNPTFEPPLPPIFGEKEGKIAKASRTRDPLYLFAALQRQLGYPEVPRYRVRDDATTKLELIQTKLRELELRIKLAESELRGSVDLSQFGKPELLKDDDE
>NZ_CP011271.1|WP_082843517.1|8930658_8930901_+|hypothetical-protein
MREVVGNPFRPVAFSHSWRTSTAVALASQMYEARDFSAMPILADALQDAGCDSADVLNHCRGPGPHVRGCWVVDLVLGKE
>NZ_CP011271.1|WP_052549516.1|8931028_8931589_+|thioredoxin-family-protein
MNLFSKFEAGLPLAEFLAKYGTDAHRARWQSATAQTTLTDDQQKLLRAFTRRTNVLVLAGAWCGDCSSQCPIFERIAEAAPVVVTRYLDRDEHADVQAALQINGGNRVPVAVFFSEDGHEVARYGERTLARYRQLVSQLTGEGCATGFVKGTDPVQQAAVQEWLDQFERVQWILRLSPRLRRLHGD
>NZ_CP011271.1|WP_082843143.1|8931723_8933631_+|hypothetical-protein
MIRYRCPHCAALTVAHERRIGQSSVCKACLKPHQIPADPTLWLSETGELLNPPAAAIPVDVRPTSISEIELPAVPFEIAETNVEPVAVVDTPPPLRIHENEITETEVESVVESATPAPVAEEPSEPFVQAPEAALELTRDADPIEEPSEPFVSAPEVHVPEPIRVNVEREPEVTRTEPLAPTPIVFAPEPITPEPIAPRVTHPIEREPWTEPVAAQKPEPESVSAVATATIPSQLVRDLPVPAPTPAPRVPERTPPPVAREATPVPPRVTIAEPVQLQTQVDITVALTAALSSRMRPPPAPRRDLRPSTAAWMLLTGAGVACVLVALFGDADLRWAALAIGATQILIGYVWIVRMTHARDPQRGLLCAIPPVTLFYLTQHKYARLRPLRFVLTGAVLAGLSAAVPALANLTQPLLAKKTPPPPPEPVAESKLAQLRTFRDQRDYKSLIKLLEILTKTDPIRSADAKDRDELATELKSLCQHQFIDVRTGALAALFRWDADPNAAVTRELCLAALRAPTQEERVNALELLPRWKDAESARAAQSLIGRSSEETHMAKTVLKNIGGPPAEQAALALLKRSEDQATRLTAIDILETVGGTESVGELRAYATATNDTVVRTRALGATTAIEERMRKPAP
>NZ_CP011271.1|WP_082843144.1|8933537_8934143_-|MarR-family-transcriptional-regulator
MSSETAPSPDGALRLAHAFANFGPAYFKWVQSQFAACGVSFARMRLLAVLHKLGPQIMSSLSDELGVTARNVTALVDALAGDGLVRRVPHATDRRATVVELTEAGARHGCMMADGSHLEMIAALFRDLTEEEQGQMLSIVTKLQGLLARRGFTNGPGGRPRPKARARDDWLYGAGLRMRSSIAVVAPRARVRTTVSFVAVA
>NZ_CP011271.1|WP_082843145.1|8934251_8936027_+|PQQ-binding-like-beta-propeller-repeat-protein
MTESTLLSPDPAPAPSRWRRALVVATIFGAGAYGFGWLAGRDDSGTIPSQAMMMSVMLGPILALLGFALWWVARGDGRFRRRVLGVVAVGASVGVSVLVAHSTMRLFAAIWGVPLTAAITGLALAAVPVVRSWPTAGLIALTALSPWLALRLDGVSGKFDMDTSYRWVPSVAERAAEQLASRATVVPTGPIAELIPESPLDWPGFRGAHRDGVVAAVAAHGWNGSAPRERWRKEPVGPAWSSFSAAGAFIYTQEQRGDSESVVCYQADTGDEVWARGEPGKHSDGPSGIGPRATPTCANGRVFAATASGTIMCLRATDGEPVWVVSLAERFGVTKPTFGYAASPLVTGNRVFINPSSKTGPRLVALDAATGATQWEVETRGTEGYSSPHPATIAGVSQVLIFNGAGLFGHDPETGRELWKYDWVTAQNEPTTVQPLALADGRIVIGGGNVGIGTRCVKVENSGSNWSASEVWKTSRFTPKFNDVVRVGKYLYGLDSGALVCLKLADGSRAWKEGQYGAGQVLLVGDNLLVVSETGQLACVAAKPDEFEELWKIDAVKGKTWNHPIIARGRLYLRNATVMVAFDLPGWSANP
>NZ_CP011271.1|WP_082843146.1|8936713_8938831_-|hypothetical-protein
MSSRRNPPLNSRRFVPRVEGLEDRTVPSGNVQIAVAGGTLFVAGDDQGNKIWIAGNGREGATVRALDATTTINGQTGPISLGGIRNDLYVRMYGGDDQLLVTGIRNRGALDVDMGAGNDTLGVSDAGQRGATVLRAGDGNDNVILNGSIFRKYLFLDTGAGDDSVTASRIGVINFGLMNPSGNDFFDRQNSTITRPVTVGTVTAGARPSVTDTDGPTVLITTTLTSPATANPLTYTVTFDEDVTGFDEADLIVTNGTVASVTARDARTYTVQVTPTSAGVVTVTVDANGAVDAAGNGNLASNTVVLTFNSSTDTTAPAAPTFDLAAASDSGTVGDLRTDASSVTLTGRAEAGATVRLYQTTVPGTPGAGSPMAEVTAAVDGTFSFTNVALNIGPNSFTVRAVDSAGNSGSTFTQTFTRNTAPTVASAITNQNLAVGAQDLVFNLTNTFVDAERVVRMMTTYPNGQTGVIDINLFANLAPATVANFLSYNYDGTIFHRLESNFVLQTGGFTFNDSGTTTATAFPPITASAPVVNEPGISNTRGTVAMAKVGGNPNSATNQFFFNLGDNSTNLDTQNGGFTVFGQVMHGGQQVVDAISGLPVFRSLDAPGAGSEPSPFPVRSGADTSNFPANINASDIATVTTVRELAAVDRMAFGATSSATGVATVSVTNGQLTVHAVASGTTTITVTATDLDGSVTQTQFTVTVP
>NZ_CP011271.1|WP_082843147.1|8939866_8940313_+|hypothetical-protein
MSTPVPDLPPIKEYKSQQYEFNDEHNREISALADAMRVTSGLMLLVGLAFVVLAALTITHTANSGGNYGPAVGLGTAALLCLCIGFWTGGAATSFRKIVETKNEDIWHLMNALGSLRSMYGLLRALIYGALVLTMIGLGLVGFALMGK
>NZ_CP011271.1|WP_082843148.1|8940402_8941365_+|TIGR01777-family-protein
MKIVLPGGSGQVGTILARHFHATGHEVVVLGRKPAPTAWRSVAWDAQTLGPWANELDGADVVVNLVGRSVNCRYTPANRREIIESRVRSVQLLGEALARSNRPPRVWLQSSTATIYAHRFDAPNDETTGIIGGNEPNAPDTWTFSIDVATSWEKALDAVHAPHTRKIAMRSAITLSPDREGVFDVLLGLVRRWLGGRSGDGKQFVSWVHEHDFIAAVEFLIQNDAMHGPVNIAAPEPLTNAEFMRVLREAWGVRFGLPAAKWMVELGAWALRTESELVLKSRRVVPGKLLEAGFKFRFPSWREAARDLCERWRQSASPVR
>NZ_CP011271.1|WP_082843149.1|8941423_8941834_-|response-regulator
MADQKLILVVDDDRELVDAMRAVLERQGYKVIQAHDGHQGKQAIYNARPDLVILDMMMPRMGGYPVLEHFKDKGDAPPIIMVTANEGSRHKVYAEYLGVIDYIRKPFAMERLLETVNKALGSGKPKEEKKEEKKAE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP011271.1	1088660-1088683	0	1.0
NZ_CP011271_10	10.66\|3908372\|37\|NZ_CP011271\|PILER-CR	3908372-3908408	37	NZ_CP011271.1	2196969-2197005	1	0.973
NZ_CP011271_10	10.71\|3908735\|36\|NZ_CP011271\|PILER-CR	3908735-3908770	36	NZ_CP011271.1	2162300-2162335	1	0.972
NZ_CP011271_10	10.109\|3908371\|37\|NZ_CP011271\|CRISPRCasFinder,CRT	3908371-3908407	37	NZ_CP011271.1	2196969-2197005	1	0.973
NZ_CP011271_10	10.114\|3908734\|36\|NZ_CP011271\|CRISPRCasFinder,CRT	3908734-3908769	36	NZ_CP011271.1	2162300-2162335	1	0.972
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP011271.1	6599389-6599412	2	0.917
NZ_CP011271_10	10.133\|3910131\|36\|NZ_CP011271\|CRISPRCasFinder,CRT	3910131-3910166	36	NZ_CP011271.1	2168325-2168360	2	0.944
NZ_CP011271_10	10.133\|3910131\|36\|NZ_CP011271\|CRISPRCasFinder,CRT	3910131-3910166	36	NZ_CP011271.1	3275862-3275897	2	0.944

1. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to position: 1088660-1088683, mismatch: 0, identity: 1.0

accgctgcggccaccgccaccacc	CRISPR spacer
accgctgcggccaccgccaccacc	Protospacer
************************

2. spacer 10.66|3908372|37|NZ_CP011271|PILER-CR matches to position: 2196969-2197005, mismatch: 1, identity: 0.973

ccggaccacggtgcgctggaacgagaacgaccgctgg	CRISPR spacer
ccggaccacggtgcgctggaacgagagcgaccgctgg	Protospacer
**************************.**********

3. spacer 10.71|3908735|36|NZ_CP011271|PILER-CR matches to position: 2162300-2162335, mismatch: 1, identity: 0.972

ggggacgtgaacggggccgcggcgcccggcgcgacg	CRISPR spacer
ggggacgtgaacggggccgcggcacccggcgcgacg	Protospacer
***********************.************

4. spacer 10.109|3908371|37|NZ_CP011271|CRISPRCasFinder,CRT matches to position: 2196969-2197005, mismatch: 1, identity: 0.973

ccggaccacggtgcgctggaacgagaacgaccgctgg	CRISPR spacer
ccggaccacggtgcgctggaacgagagcgaccgctgg	Protospacer
**************************.**********

5. spacer 10.114|3908734|36|NZ_CP011271|CRISPRCasFinder,CRT matches to position: 2162300-2162335, mismatch: 1, identity: 0.972

ggggacgtgaacggggccgcggcgcccggcgcgacg	CRISPR spacer
ggggacgtgaacggggccgcggcacccggcgcgacg	Protospacer
***********************.************

6. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to position: 6599389-6599412, mismatch: 2, identity: 0.917

accgctgcggccaccgccaccacc	CRISPR spacer
accgctgcgaccactgccaccacc	Protospacer
*********.****.*********

7. spacer 10.133|3910131|36|NZ_CP011271|CRISPRCasFinder,CRT matches to position: 2168325-2168360, mismatch: 2, identity: 0.944

aggtcgggggaccactcggagacctgtgcgagcgcc	CRISPR spacer
aggtccggcgaccactcggagacctgtgcgagcgcc	Protospacer
***** ** ***************************

8. spacer 10.133|3910131|36|NZ_CP011271|CRISPRCasFinder,CRT matches to position: 3275862-3275897, mismatch: 2, identity: 0.944

aggtcgggggaccactcggagacctgtgcgagcgcc	CRISPR spacer
aggtccggcgaccactcggagacctgtgcgagcgcc	Protospacer
***** ** ***************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	CP054934	Nocardiopsis flavescens strain NA01583 plasmid unnamed1, complete sequence	119754-119777	2	0.917
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP049751	Rhodococcus fascians A21d2 plasmid unnamed2, complete sequence	38669-38692	2	0.917
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	737356-737379	2	0.917
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	744653-744676	2	0.917
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP031166	Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence	113870-113893	2	0.917
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	MN657133	Cryobacterium sp. strain ANT_H10B plasmid pA10BH1, complete sequence	37037-37060	2	0.917
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	AP018462	Mycobacterium phage D12 DNA, complete genome	19659-19682	2	0.917
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	MK494131	Mycobacterium phage GodPhather, complete genome	19921-19944	2	0.917
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	MK524486	Mycobacterium phage Waleliano, complete genome	20968-20991	2	0.917
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	MH513970	Mycobacterium phage Hangman, complete genome	20968-20991	2	0.917
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	AP018463	Mycobacterium phage PR DNA, complete genome	19636-19659	2	0.917
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	MH001450	Mycobacterium phage Jeon, complete genome	19663-19686	2	0.917
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NC_042035	Mycobacterium phage Zemanar, complete sequence	20968-20991	2	0.917
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_MG958650	Pseudomonas aeruginosa strain PA41437 plasmid pOXA-198, complete sequence	29233-29256	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP006374	Aureimonas sp. AU20 plasmid pAU20g, complete sequence	4321-4344	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP029211	Aquabacterium olei strain NBRC 110486 plasmid pTB101, complete sequence	100722-100745	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	478733-478756	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	628453-628476	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	MN657146	Cryobacterium sp. strain ANT_H28B plasmid pA28BH2, complete sequence	19963-19986	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	222439-222462	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	828900-828923	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_AP012556	Mycobacterium avium subsp. hominissuis TH135 plasmid pMAH135, complete sequence	68134-68157	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_AP012556	Mycobacterium avium subsp. hominissuis TH135 plasmid pMAH135, complete sequence	116475-116498	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP016850	Pseudomonas sp. TMW 2.1634 plasmid pL21564-1, complete sequence	41774-41797	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	JN831654	Mycobacterium virus Saintus, complete genome	28269-28292	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	1227131-1227154	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP023152	Mycobacterium chimaera strain FLAC0070 plasmid pFLAC0070_1, complete sequence	24890-24913	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP023152	Mycobacterium chimaera strain FLAC0070 plasmid pFLAC0070_1, complete sequence	71960-71983	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP009146	Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence	1341009-1341032	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NC_014811	Mycolicibacterium gilvum Spyr1 plasmid pMSPYR101, complete sequence	201682-201705	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP021831	Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence	1586397-1586420	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	172925-172948	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP016560	Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence	486117-486140	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	MN234212	Mycobacterium phage Paphu, complete genome	28409-28432	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	KX574454	Mycobacterium phage PacerPaul, complete genome	28528-28551	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	MG925351	Mycobacterium phage MPlant7149, complete genome	28208-28231	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	MK524497	Mycobacterium phage Francis47, complete genome	29162-29185	3	0.875
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP017185	Enterobacter roggenkampii strain DSM 16690 plasmid pDSMZ16690, complete sequence	98307-98330	4	0.833
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	NZ_CP015882	Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence	233066-233089	4	0.833
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	MN585991	Mycobacterium phage Snazzy, complete genome	28714-28737	4	0.833
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	MK359331	Mycobacterium phage Rajelicia, complete genome	28595-28618	4	0.833
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	MH744414	Mycobacterium phage Arcanine, complete genome	28567-28590	4	0.833
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	MN119379	Mycobacterium phage Anglerfish, complete genome	29134-29157	4	0.833
NZ_CP011271_3	3.1\|1088621\|24\|NZ_CP011271\|CRISPRCasFinder	1088621-1088644	24	KJ028219	Mycobacterium phage 32HC, complete genome	24621-24644	4	0.833
NZ_CP011271_10	10.25\|3905394\|35\|NZ_CP011271\|PILER-CR,CRISPRCasFinder,CRT	3905394-3905428	35	JQ807246	Environmental Halophage eHP-27, partial genome	1431-1465	7	0.8
NZ_CP011271_10	10.38\|3906340\|34\|NZ_CP011271\|PILER-CR,CRISPRCasFinder,CRT	3906340-3906373	34	MK814759	Gordonia phage Reyja, complete genome	20012-20045	8	0.765
NZ_CP011271_10	10.38\|3906340\|34\|NZ_CP011271\|PILER-CR,CRISPRCasFinder,CRT	3906340-3906373	34	NZ_CP032520	Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence	414991-415024	8	0.765
NZ_CP011271_10	10.78\|3909250\|32\|NZ_CP011271\|PILER-CR	3909250-3909281	32	NC_019848	Sinorhizobium meliloti GR4 plasmid pRmeGR4c, complete sequence	829390-829421	8	0.75
NZ_CP011271_10	10.78\|3909250\|32\|NZ_CP011271\|PILER-CR	3909250-3909281	32	NZ_CP017242	Rhizobium etli 8C-3 plasmid pRsp8C3a, complete sequence	172079-172110	8	0.75
NZ_CP011271_10	10.78\|3909250\|32\|NZ_CP011271\|PILER-CR	3909250-3909281	32	NZ_CP043960	Streptomyces tendae strain 139 plasmid unnamed1, complete sequence	6114-6145	8	0.75
NZ_CP011271_10	10.121\|3909249\|32\|NZ_CP011271\|CRISPRCasFinder,CRT	3909249-3909280	32	NC_019848	Sinorhizobium meliloti GR4 plasmid pRmeGR4c, complete sequence	829390-829421	8	0.75
NZ_CP011271_10	10.121\|3909249\|32\|NZ_CP011271\|CRISPRCasFinder,CRT	3909249-3909280	32	NZ_CP017242	Rhizobium etli 8C-3 plasmid pRsp8C3a, complete sequence	172079-172110	8	0.75
NZ_CP011271_10	10.121\|3909249\|32\|NZ_CP011271\|CRISPRCasFinder,CRT	3909249-3909280	32	NZ_CP043960	Streptomyces tendae strain 139 plasmid unnamed1, complete sequence	6114-6145	8	0.75
NZ_CP011271_10	10.34\|3906053\|36\|NZ_CP011271\|PILER-CR,CRISPRCasFinder,CRT	3906053-3906088	36	NZ_CP045856	Agrobacterium sp. MA01 plasmid punanmed2, complete sequence	289034-289069	9	0.75
NZ_CP011271_10	10.75\|3909032\|37\|NZ_CP011271\|PILER-CR	3909032-3909068	37	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	988326-988362	9	0.757
NZ_CP011271_10	10.75\|3909032\|37\|NZ_CP011271\|PILER-CR	3909032-3909068	37	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	897752-897788	9	0.757
NZ_CP011271_10	10.75\|3909032\|37\|NZ_CP011271\|PILER-CR	3909032-3909068	37	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	988333-988369	9	0.757
NZ_CP011271_10	10.75\|3909032\|37\|NZ_CP011271\|PILER-CR	3909032-3909068	37	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	799512-799548	9	0.757
NZ_CP011271_10	10.75\|3909032\|37\|NZ_CP011271\|PILER-CR	3909032-3909068	37	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	799502-799538	9	0.757
NZ_CP011271_10	10.75\|3909032\|37\|NZ_CP011271\|PILER-CR	3909032-3909068	37	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	917896-917932	9	0.757
NZ_CP011271_10	10.75\|3909032\|37\|NZ_CP011271\|PILER-CR	3909032-3909068	37	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	877248-877284	9	0.757
NZ_CP011271_10	10.118\|3909031\|37\|NZ_CP011271\|CRISPRCasFinder,CRT	3909031-3909067	37	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	988326-988362	9	0.757
NZ_CP011271_10	10.118\|3909031\|37\|NZ_CP011271\|CRISPRCasFinder,CRT	3909031-3909067	37	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	897752-897788	9	0.757
NZ_CP011271_10	10.118\|3909031\|37\|NZ_CP011271\|CRISPRCasFinder,CRT	3909031-3909067	37	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	988333-988369	9	0.757
NZ_CP011271_10	10.118\|3909031\|37\|NZ_CP011271\|CRISPRCasFinder,CRT	3909031-3909067	37	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	799512-799548	9	0.757
NZ_CP011271_10	10.118\|3909031\|37\|NZ_CP011271\|CRISPRCasFinder,CRT	3909031-3909067	37	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	799502-799538	9	0.757
NZ_CP011271_10	10.118\|3909031\|37\|NZ_CP011271\|CRISPRCasFinder,CRT	3909031-3909067	37	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	917896-917932	9	0.757
NZ_CP011271_10	10.118\|3909031\|37\|NZ_CP011271\|CRISPRCasFinder,CRT	3909031-3909067	37	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	877248-877284	9	0.757
NZ_CP011271_10	10.135\|3910274\|36\|NZ_CP011271\|CRISPRCasFinder,CRT,PILER-CR	3910274-3910309	36	NZ_CP010990	Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence	116213-116248	9	0.75
NZ_CP011271_10	10.135\|3910274\|36\|NZ_CP011271\|CRISPRCasFinder,CRT,PILER-CR	3910274-3910309	36	NZ_CP012186	Pseudonocardia sp. EC080619-01 plasmid pBCI1-1, complete sequence	104555-104590	9	0.75
NZ_CP011271_10	10.136\|3910346\|36\|NZ_CP011271\|CRISPRCasFinder,CRT,PILER-CR	3910346-3910381	36	NZ_CP040096	Pantoea sp. SO10 plasmid unnamed1, complete sequence	543488-543523	9	0.75
NZ_CP011271_10	10.38\|3906340\|34\|NZ_CP011271\|PILER-CR,CRISPRCasFinder,CRT	3906340-3906373	34	NZ_CP006369	Aureimonas sp. AU20 plasmid pAU20b, complete sequence	330212-330245	10	0.706
NZ_CP011271_10	10.38\|3906340\|34\|NZ_CP011271\|PILER-CR,CRISPRCasFinder,CRT	3906340-3906373	34	KR080206	Mycobacterium phage ShedlockHolmes, complete genome	52455-52488	10	0.706
NZ_CP011271_10	10.64\|3908227\|37\|NZ_CP011271\|PILER-CR	3908227-3908263	37	NZ_CP049158	Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence	390747-390783	10	0.73
NZ_CP011271_10	10.64\|3908227\|37\|NZ_CP011271\|PILER-CR	3908227-3908263	37	NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	389956-389992	10	0.73
NZ_CP011271_10	10.75\|3909032\|37\|NZ_CP011271\|PILER-CR	3909032-3909068	37	NZ_AP022333	Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49a, complete sequence	166755-166791	10	0.73
NZ_CP011271_10	10.107\|3908226\|37\|NZ_CP011271\|CRISPRCasFinder,CRT	3908226-3908262	37	NZ_CP049158	Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence	390747-390783	10	0.73
NZ_CP011271_10	10.107\|3908226\|37\|NZ_CP011271\|CRISPRCasFinder,CRT	3908226-3908262	37	NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	389956-389992	10	0.73
NZ_CP011271_10	10.118\|3909031\|37\|NZ_CP011271\|CRISPRCasFinder,CRT	3909031-3909067	37	NZ_AP022333	Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49a, complete sequence	166755-166791	10	0.73
NZ_CP011271_10	10.78\|3909250\|32\|NZ_CP011271\|PILER-CR	3909250-3909281	32	NZ_CP017750	Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence	112265-112296	11	0.656
NZ_CP011271_10	10.121\|3909249\|32\|NZ_CP011271\|CRISPRCasFinder,CRT	3909249-3909280	32	NZ_CP017750	Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence	112265-112296	11	0.656
NZ_CP011271_10	10.141\|3910706\|38\|NZ_CP011271\|CRISPRCasFinder,CRT,PILER-CR	3910706-3910743	38	NZ_LT703506	Mycobacterium chimaera strain Mycobacterium chimaera MC045 isolate Mycobacterium chimaera plasmid 2	250019-250056	11	0.711
NZ_CP011271_10	10.153\|3911588\|37\|NZ_CP011271\|CRISPRCasFinder,CRT,PILER-CR	3911588-3911624	37	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	53382-53418	11	0.703
NZ_CP011271_10	10.153\|3911588\|37\|NZ_CP011271\|CRISPRCasFinder,CRT,PILER-CR	3911588-3911624	37	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	17409-17445	11	0.703

1. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to CP054934 (Nocardiopsis flavescens strain NA01583 plasmid unnamed1, complete sequence) position: , mismatch: 2, identity: 0.917

accgctgcggccaccgccaccacc	CRISPR spacer
accgctgcggccaccgccaccggc	Protospacer
*********************. *

2. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_CP049751 (Rhodococcus fascians A21d2 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.917

accgctgcggccaccgccaccacc	CRISPR spacer
accgcggccgccaccgccaccacc	Protospacer
***** ** ***************

3. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 2, identity: 0.917

accgctgcggccaccgccaccacc	CRISPR spacer
accgcggcggccgccgccaccacc	Protospacer
***** ******.***********

4. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 2, identity: 0.917

accgctgcggccaccgccaccacc	CRISPR spacer
accgccgcggcaaccgccaccacc	Protospacer
*****.***** ************

5. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_CP031166 (Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence) position: , mismatch: 2, identity: 0.917

accgctgcggccaccgccaccacc	CRISPR spacer
acccctgcggccaccggcaccacc	Protospacer
*** ************ *******

6. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to MN657133 (Cryobacterium sp. strain ANT_H10B plasmid pA10BH1, complete sequence) position: , mismatch: 2, identity: 0.917

accgctgcggccaccgccaccacc	CRISPR spacer
accgccgccgccaccgccaccacc	Protospacer
*****.** ***************

7. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to AP018462 (Mycobacterium phage D12 DNA, complete genome) position: , mismatch: 2, identity: 0.917

accgctgcggccaccgccaccacc	CRISPR spacer
accgccacggccaccgccaccacc	Protospacer
*****..*****************

8. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to MK494131 (Mycobacterium phage GodPhather, complete genome) position: , mismatch: 2, identity: 0.917

accgctgcggccaccgccaccacc	CRISPR spacer
accgccgcggccaccgccgccacc	Protospacer
*****.************.*****

9. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to MK524486 (Mycobacterium phage Waleliano, complete genome) position: , mismatch: 2, identity: 0.917

accgctgcggccaccgccaccacc	CRISPR spacer
accgccccggccaccgccaccacc	Protospacer
*****. *****************

10. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to MH513970 (Mycobacterium phage Hangman, complete genome) position: , mismatch: 2, identity: 0.917

accgctgcggccaccgccaccacc	CRISPR spacer
accgccccggccaccgccaccacc	Protospacer
*****. *****************

11. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to AP018463 (Mycobacterium phage PR DNA, complete genome) position: , mismatch: 2, identity: 0.917

accgctgcggccaccgccaccacc	CRISPR spacer
accgccacggccaccgccaccacc	Protospacer
*****..*****************

12. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to MH001450 (Mycobacterium phage Jeon, complete genome) position: , mismatch: 2, identity: 0.917

accgctgcggccaccgccaccacc	CRISPR spacer
accgccgcggccaccgccgccacc	Protospacer
*****.************.*****

13. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NC_042035 (Mycobacterium phage Zemanar, complete sequence) position: , mismatch: 2, identity: 0.917

accgctgcggccaccgccaccacc	CRISPR spacer
accgccccggccaccgccaccacc	Protospacer
*****. *****************

14. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_MG958650 (Pseudomonas aeruginosa strain PA41437 plasmid pOXA-198, complete sequence) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
accgctgcggccaccgccaccgtt	Protospacer
*********************...

15. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_CP006374 (Aureimonas sp. AU20 plasmid pAU20g, complete sequence) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
gccgctgcggccaccgccaccggc	Protospacer
.********************. *

16. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_CP029211 (Aquabacterium olei strain NBRC 110486 plasmid pTB101, complete sequence) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
accgcagcggccaccgccaccagg	Protospacer
***** ****************

17. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
tccgccgcggccaccgccgccacc	Protospacer
 ****.************.*****

18. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
gccgctgcggccaccaccgccacc	Protospacer
.**************.**.*****

19. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to MN657146 (Cryobacterium sp. strain ANT_H28B plasmid pA28BH2, complete sequence) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
gccggtgcggccaccgccagcacc	Protospacer
.*** ************** ****

20. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
accgctgccgccaccgccaccgac	Protospacer
******** ************. *

21. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
accgctgccgccaccgccaccgac	Protospacer
******** ************. *

22. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_AP012556 (Mycobacterium avium subsp. hominissuis TH135 plasmid pMAH135, complete sequence) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
acagcggcggccaccgccaccacg	Protospacer
** ** *****************

23. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_AP012556 (Mycobacterium avium subsp. hominissuis TH135 plasmid pMAH135, complete sequence) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
acagcggcggccaccgccaccacg	Protospacer
** ** *****************

24. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_CP016850 (Pseudomonas sp. TMW 2.1634 plasmid pL21564-1, complete sequence) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
gccgctgccaccaccgccaccacc	Protospacer
.******* .**************

25. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to JN831654 (Mycobacterium virus Saintus, complete genome) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
cccggagcggccaccgccaccacc	Protospacer
 ***  ******************

26. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
accgctgccgccaccgccaccgac	Protospacer
******** ************. *

27. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_CP023152 (Mycobacterium chimaera strain FLAC0070 plasmid pFLAC0070_1, complete sequence) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
acagcggcggccaccgccaccacg	Protospacer
** ** *****************

28. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_CP023152 (Mycobacterium chimaera strain FLAC0070 plasmid pFLAC0070_1, complete sequence) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
acagcggcggccaccgccaccacg	Protospacer
** ** *****************

29. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_CP009146 (Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
gcggctgcggccaccggcaccacc	Protospacer
.* ************* *******

30. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NC_014811 (Mycolicibacterium gilvum Spyr1 plasmid pMSPYR101, complete sequence) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
accgccgaggccaccgccaccacg	Protospacer
*****.* ***************

31. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_CP021831 (Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
gcggctgcggccaccggcaccacc	Protospacer
.* ************* *******

32. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
accgcggcggccaccgccatcacg	Protospacer
***** *************.***

33. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_CP016560 (Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
accgctgccgccaccgccaccgac	Protospacer
******** ************. *

34. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to MN234212 (Mycobacterium phage Paphu, complete genome) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
cccgctgccgccaccaccaccacc	Protospacer
 ******* ******.********

35. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to KX574454 (Mycobacterium phage PacerPaul, complete genome) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
cccgctgccgccaccaccaccacc	Protospacer
 ******* ******.********

36. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to MG925351 (Mycobacterium phage MPlant7149, complete genome) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
cccgctgccgccaccaccaccacc	Protospacer
 ******* ******.********

37. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to MK524497 (Mycobacterium phage Francis47, complete genome) position: , mismatch: 3, identity: 0.875

accgctgcggccaccgccaccacc	CRISPR spacer
cccgctgccgccaccaccaccacc	Protospacer
 ******* ******.********

38. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_CP017185 (Enterobacter roggenkampii strain DSM 16690 plasmid pDSMZ16690, complete sequence) position: , mismatch: 4, identity: 0.833

accgctgcggccaccgccaccacc	CRISPR spacer
ctggctgccgccaccgccaccacc	Protospacer
 . ***** ***************

39. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to NZ_CP015882 (Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence) position: , mismatch: 4, identity: 0.833

accgctgcggccaccgccaccacc	CRISPR spacer
tttgctgccgccaccgccaccacc	Protospacer
 ..***** ***************

40. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to MN585991 (Mycobacterium phage Snazzy, complete genome) position: , mismatch: 4, identity: 0.833

accgctgcggccaccgccaccacc	CRISPR spacer
gttgttgcggccaccgccaccacc	Protospacer
...*.*******************

41. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to MK359331 (Mycobacterium phage Rajelicia, complete genome) position: , mismatch: 4, identity: 0.833

accgctgcggccaccgccaccacc	CRISPR spacer
gttgttgcggccaccgccaccacc	Protospacer
...*.*******************

42. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to MH744414 (Mycobacterium phage Arcanine, complete genome) position: , mismatch: 4, identity: 0.833

accgctgcggccaccgccaccacc	CRISPR spacer
gttgttgcggccaccgccaccacc	Protospacer
...*.*******************

43. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to MN119379 (Mycobacterium phage Anglerfish, complete genome) position: , mismatch: 4, identity: 0.833

accgctgcggccaccgccaccacc	CRISPR spacer
gttgttgcggccaccgccaccacc	Protospacer
...*.*******************

44. spacer 3.1|1088621|24|NZ_CP011271|CRISPRCasFinder matches to KJ028219 (Mycobacterium phage 32HC, complete genome) position: , mismatch: 4, identity: 0.833

accgctgcggccaccgccaccacc	CRISPR spacer
gaagctgcggccaccgccgccacc	Protospacer
.  ***************.*****

45. spacer 10.25|3905394|35|NZ_CP011271|PILER-CR,CRISPRCasFinder,CRT matches to JQ807246 (Environmental Halophage eHP-27, partial genome) position: , mismatch: 7, identity: 0.8

ctcgcgggcatcggcgtgggtgccgtcggttcgtt	CRISPR spacer
atcgcgggcatcggcgtggtggccgtccgagcgat	Protospacer
 ******************  ****** *  ** *

46. spacer 10.38|3906340|34|NZ_CP011271|PILER-CR,CRISPRCasFinder,CRT matches to MK814759 (Gordonia phage Reyja, complete genome) position: , mismatch: 8, identity: 0.765

ttttcggcgagttcttcgagcgtgacccgatcgc	CRISPR spacer
ttggcggcgagttcttcgaacgtgtcccactctt	Protospacer
**  ***************.**** ***. ** .

47. spacer 10.38|3906340|34|NZ_CP011271|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032520 (Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

ttttcggcgagttcttcgagcgtgacccgatcgc	CRISPR spacer
tgttcggcgatatcttcgagcgtgacaacctcga	Protospacer
* ********  **************    ***

48. spacer 10.78|3909250|32|NZ_CP011271|PILER-CR matches to NC_019848 (Sinorhizobium meliloti GR4 plasmid pRmeGR4c, complete sequence) position: , mismatch: 8, identity: 0.75

aacgtcctcgcgccgcaggaccgaggggccga	CRISPR spacer
aacttcctcgcgccgcaggcccggtgtgcgac	Protospacer
*** *************** ***. * ** .

49. spacer 10.78|3909250|32|NZ_CP011271|PILER-CR matches to NZ_CP017242 (Rhizobium etli 8C-3 plasmid pRsp8C3a, complete sequence) position: , mismatch: 8, identity: 0.75

aacgtcctcgcgccgcaggaccgaggggccga	CRISPR spacer
aacttcctcgcgccgcaggcccggtgtgcgac	Protospacer
*** *************** ***. * ** .

50. spacer 10.78|3909250|32|NZ_CP011271|PILER-CR matches to NZ_CP043960 (Streptomyces tendae strain 139 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

aacgt-cctcgcgccgcaggaccgaggggccga	CRISPR spacer
-ccgcgctccgggccgcgggaccgaggggccgt	Protospacer
  **. *..** *****.**************

51. spacer 10.121|3909249|32|NZ_CP011271|CRISPRCasFinder,CRT matches to NC_019848 (Sinorhizobium meliloti GR4 plasmid pRmeGR4c, complete sequence) position: , mismatch: 8, identity: 0.75

aacgtcctcgcgccgcaggaccgaggggccga	CRISPR spacer
aacttcctcgcgccgcaggcccggtgtgcgac	Protospacer
*** *************** ***. * ** .

52. spacer 10.121|3909249|32|NZ_CP011271|CRISPRCasFinder,CRT matches to NZ_CP017242 (Rhizobium etli 8C-3 plasmid pRsp8C3a, complete sequence) position: , mismatch: 8, identity: 0.75

aacgtcctcgcgccgcaggaccgaggggccga	CRISPR spacer
aacttcctcgcgccgcaggcccggtgtgcgac	Protospacer
*** *************** ***. * ** .

53. spacer 10.121|3909249|32|NZ_CP011271|CRISPRCasFinder,CRT matches to NZ_CP043960 (Streptomyces tendae strain 139 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

aacgt-cctcgcgccgcaggaccgaggggccga	CRISPR spacer
-ccgcgctccgggccgcgggaccgaggggccgt	Protospacer
  **. *..** *****.**************

54. spacer 10.34|3906053|36|NZ_CP011271|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045856 (Agrobacterium sp. MA01 plasmid punanmed2, complete sequence) position: , mismatch: 9, identity: 0.75

gcgccgaccgaggaccagtcgaaggagctgctcggg	CRISPR spacer
ccagccatcgaggaccagttgaaggcgctgctcgcc	Protospacer
 *. * *.***********.***** ********

55. spacer 10.75|3909032|37|NZ_CP011271|PILER-CR matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

cttggcggcctggtcgcgctccagctgggcgagttgc	CRISPR spacer
ctcggcggccgggtcgcgctccagctgcagcgcatgc	Protospacer
**.******* **************** .  .  ***

56. spacer 10.75|3909032|37|NZ_CP011271|PILER-CR matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 9, identity: 0.757

cttggcggcctggtcgcgctccagctgggcgagttgc	CRISPR spacer
ctcggcggccgggtcgcgctccagctgcagcgcatgc	Protospacer
**.******* **************** .  .  ***

57. spacer 10.75|3909032|37|NZ_CP011271|PILER-CR matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

cttggcggcctggtcgcgctccagctgggcgagttgc	CRISPR spacer
ctcggcggccgggtcgcgctccagctgcagcgcatgc	Protospacer
**.******* **************** .  .  ***

58. spacer 10.75|3909032|37|NZ_CP011271|PILER-CR matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

cttggcggcctggtcgcgctccagctgggcgagttgc	CRISPR spacer
ctcggcggccgggtcgcgctccagctgcagcgcatgc	Protospacer
**.******* **************** .  .  ***

59. spacer 10.75|3909032|37|NZ_CP011271|PILER-CR matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

cttggcggcctggtcgcgctccagctgggcgagttgc	CRISPR spacer
ctcggcggccgggtcgcgctccagctgcagcgcatgc	Protospacer
**.******* **************** .  .  ***

60. spacer 10.75|3909032|37|NZ_CP011271|PILER-CR matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

cttggcggcctggtcgcgctccagctgggcgagttgc	CRISPR spacer
ctcggcggccgggtcgcgctccagctgcagcgcatgc	Protospacer
**.******* **************** .  .  ***

61. spacer 10.75|3909032|37|NZ_CP011271|PILER-CR matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

cttggcggcctggtcgcgctccagctgggcgagttgc	CRISPR spacer
ctcggcggccgggtcgcgctccagctgcagcgcatgc	Protospacer
**.******* **************** .  .  ***

62. spacer 10.118|3909031|37|NZ_CP011271|CRISPRCasFinder,CRT matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

cttggcggcctggtcgcgctccagctgggcgagttgc	CRISPR spacer
ctcggcggccgggtcgcgctccagctgcagcgcatgc	Protospacer
**.******* **************** .  .  ***

63. spacer 10.118|3909031|37|NZ_CP011271|CRISPRCasFinder,CRT matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 9, identity: 0.757

cttggcggcctggtcgcgctccagctgggcgagttgc	CRISPR spacer
ctcggcggccgggtcgcgctccagctgcagcgcatgc	Protospacer
**.******* **************** .  .  ***

64. spacer 10.118|3909031|37|NZ_CP011271|CRISPRCasFinder,CRT matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

cttggcggcctggtcgcgctccagctgggcgagttgc	CRISPR spacer
ctcggcggccgggtcgcgctccagctgcagcgcatgc	Protospacer
**.******* **************** .  .  ***

65. spacer 10.118|3909031|37|NZ_CP011271|CRISPRCasFinder,CRT matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

cttggcggcctggtcgcgctccagctgggcgagttgc	CRISPR spacer
ctcggcggccgggtcgcgctccagctgcagcgcatgc	Protospacer
**.******* **************** .  .  ***

66. spacer 10.118|3909031|37|NZ_CP011271|CRISPRCasFinder,CRT matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

cttggcggcctggtcgcgctccagctgggcgagttgc	CRISPR spacer
ctcggcggccgggtcgcgctccagctgcagcgcatgc	Protospacer
**.******* **************** .  .  ***

67. spacer 10.118|3909031|37|NZ_CP011271|CRISPRCasFinder,CRT matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

cttggcggcctggtcgcgctccagctgggcgagttgc	CRISPR spacer
ctcggcggccgggtcgcgctccagctgcagcgcatgc	Protospacer
**.******* **************** .  .  ***

68. spacer 10.118|3909031|37|NZ_CP011271|CRISPRCasFinder,CRT matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

cttggcggcctggtcgcgctccagctgggcgagttgc	CRISPR spacer
ctcggcggccgggtcgcgctccagctgcagcgcatgc	Protospacer
**.******* **************** .  .  ***

69. spacer 10.135|3910274|36|NZ_CP011271|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP010990 (Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence) position: , mismatch: 9, identity: 0.75

gcctcaacgtcgtccttgtcgctggcgagcacggtc	CRISPR spacer
accggcacgtcgtccttgtcgccggcgagcccgtgg	Protospacer
.**   ****************.******* **

70. spacer 10.135|3910274|36|NZ_CP011271|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012186 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-1, complete sequence) position: , mismatch: 9, identity: 0.75

gcctcaacgtcgtccttgtcgctggcgagcacggtc	CRISPR spacer
accggcacgtcgtccttgtcgccggcgagcccgtgg	Protospacer
.**   ****************.******* **

71. spacer 10.136|3910346|36|NZ_CP011271|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP040096 (Pantoea sp. SO10 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.75

tggcccccgcggtgatcgacgggattgacgtcggta	CRISPR spacer
gcggtcaggtggtgattgacgggattgacctcggta	Protospacer
  * .*  *.******.************ ******

72. spacer 10.38|3906340|34|NZ_CP011271|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP006369 (Aureimonas sp. AU20 plasmid pAU20b, complete sequence) position: , mismatch: 10, identity: 0.706

ttttcggcgagttcttcgagcgtgacccgatcgc	CRISPR spacer
aggctgtcgagatcttcgagcgtgccccgatggg	Protospacer
   ..* **** ************ ****** *

73. spacer 10.38|3906340|34|NZ_CP011271|PILER-CR,CRISPRCasFinder,CRT matches to KR080206 (Mycobacterium phage ShedlockHolmes, complete genome) position: , mismatch: 10, identity: 0.706

ttttcggcgagttcttcgagcgtgacccgatcgc	CRISPR spacer
gtttcggcgagttgatcgagcgtgagttcggcgg	Protospacer
 ************  ********** .. . **

74. spacer 10.64|3908227|37|NZ_CP011271|PILER-CR matches to NZ_CP049158 (Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence) position: , mismatch: 10, identity: 0.73

caccgcctgcgtccggaccggcccgaagtccaggcat	CRISPR spacer
taccgcctgctgccggaccggcccgaagcaaacccgg	Protospacer
.*********  ****************.  *  *.

75. spacer 10.64|3908227|37|NZ_CP011271|PILER-CR matches to NZ_CP049318 (Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence) position: , mismatch: 10, identity: 0.73

caccgcctgcgtccggaccggcccgaagtccaggcat	CRISPR spacer
taccgcctgctgccggaccggcccgaagcaaacccgg	Protospacer
.*********  ****************.  *  *.

76. spacer 10.75|3909032|37|NZ_CP011271|PILER-CR matches to NZ_AP022333 (Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49a, complete sequence) position: , mismatch: 10, identity: 0.73

cttggcggcctggtcgcgctccagctgggcgagttgc	CRISPR spacer
gttggcggcttggtcgcgctcgagctgaaagcctatc	Protospacer
 ********.*********** *****.. *  *  *

77. spacer 10.107|3908226|37|NZ_CP011271|CRISPRCasFinder,CRT matches to NZ_CP049158 (Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence) position: , mismatch: 10, identity: 0.73

caccgcctgcgtccggaccggcccgaagtccaggcat	CRISPR spacer
taccgcctgctgccggaccggcccgaagcaaacccgg	Protospacer
.*********  ****************.  *  *.

78. spacer 10.107|3908226|37|NZ_CP011271|CRISPRCasFinder,CRT matches to NZ_CP049318 (Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence) position: , mismatch: 10, identity: 0.73

caccgcctgcgtccggaccggcccgaagtccaggcat	CRISPR spacer
taccgcctgctgccggaccggcccgaagcaaacccgg	Protospacer
.*********  ****************.  *  *.

79. spacer 10.118|3909031|37|NZ_CP011271|CRISPRCasFinder,CRT matches to NZ_AP022333 (Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49a, complete sequence) position: , mismatch: 10, identity: 0.73

cttggcggcctggtcgcgctccagctgggcgagttgc	CRISPR spacer
gttggcggcttggtcgcgctcgagctgaaagcctatc	Protospacer
 ********.*********** *****.. *  *  *

80. spacer 10.78|3909250|32|NZ_CP011271|PILER-CR matches to NZ_CP017750 (Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.656

aacgtcctcgcgccgcaggaccgaggggccga	CRISPR spacer
ggcgtcctcgcgcaggaggaccgagttcttag	Protospacer
..*********** * *********   ....

81. spacer 10.121|3909249|32|NZ_CP011271|CRISPRCasFinder,CRT matches to NZ_CP017750 (Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.656

aacgtcctcgcgccgcaggaccgaggggccga	CRISPR spacer
ggcgtcctcgcgcaggaggaccgagttcttag	Protospacer
..*********** * *********   ....

82. spacer 10.141|3910706|38|NZ_CP011271|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LT703506 (Mycobacterium chimaera strain Mycobacterium chimaera MC045 isolate Mycobacterium chimaera plasmid 2) position: , mismatch: 11, identity: 0.711

gtggcagttccgtcgaagaacatcacgtcgacggagga	CRISPR spacer
ttctgttctccgtcgaagaacatcacgccggcggagtt	Protospacer
 *     .*******************.**.*****

83. spacer 10.153|3911588|37|NZ_CP011271|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 11, identity: 0.703

gcttccggccgcgccgctggcaccggtccgccaccgt	CRISPR spacer
gcccggggccccgccgctggcaccggaccgccgggcg	Protospacer
**..  **** *************** *****.

84. spacer 10.153|3911588|37|NZ_CP011271|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 11, identity: 0.703

gcttccggccgcgccgctggcaccggtccgccaccgt	CRISPR spacer
gcccggggccccgccgctggcaccggaccgccgggcg	Protospacer
**..  **** *************** *****.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

777859 : 835394

Synechococcus_phage(25.0%)

protease,tail,head,portal,transposase,capsid

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_082838461.1\|777859_778633_-\|transposase	IS1595 family transposase	NA	NA	NA	NA
WP_052553503.1\|780423_781860_+	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_082838463.1\|784682_785633_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_082838464.1\|785798_787517_+	hypothetical protein	NA	NA	NA	NA
WP_082838465.1\|787567_788962_+	DUF1800 domain-containing protein	NA	NA	NA	NA
WP_052553453.1\|789101_790343_+	DUF1501 domain-containing protein	NA	NA	NA	NA
WP_082838466.1\|790473_792612_+	hypothetical protein	NA	NA	NA	NA
WP_052553450.1\|792629_793412_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_052553449.1\|793422_794634_-	2-oxo acid dehydrogenase subunit E2	NA	NA	NA	NA
WP_082838467.1\|794638_796618_-	dehydrogenase	E3SJ83	Synechococcus_phage	3.2e-08	26.1
WP_082838468.1\|796610_797942_-	MFS transporter	NA	NA	NA	NA
WP_082838469.1\|798165_799173_-	DUF1963 domain-containing protein	NA	NA	NA	NA
WP_157469137.1\|799580_800210_-	hypothetical protein	NA	NA	NA	NA
WP_082838471.1\|800677_801154_-	hypothetical protein	NA	NA	NA	NA
WP_082838472.1\|801156_802395_-	peptidase T	NA	NA	NA	NA
WP_082838473.1\|802445_803195_-	endonuclease III	NA	NA	NA	NA
WP_157469139.1\|803196_804036_-	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_052553434.1\|804154_805135_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_052553432.1\|805131_805902_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.8e-22	33.5
WP_162271570.1\|806073_809025_-	hypothetical protein	NA	NA	NA	NA
WP_157469141.1\|809494_809671_+	hypothetical protein	NA	NA	NA	NA
WP_052553425.1\|809697_810381_-	2OG-Fe(II) oxygenase	H8ZNB4	Synechococcus_phage	9.0e-19	44.9
WP_162271571.1\|810972_811749_+	hypothetical protein	NA	NA	NA	NA
WP_052553420.1\|811882_812317_+	hypothetical protein	NA	NA	NA	NA
WP_052553418.1\|812448_813438_+	CoA transferase subunit A	NA	NA	NA	NA
WP_082838477.1\|813469_814459_-	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_157469143.1\|815066_815282_-	hypothetical protein	NA	NA	NA	NA
WP_157469145.1\|815429_816065_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_157469147.1\|816043_816817_-	hypothetical protein	NA	NA	NA	NA
WP_082838479.1\|817063_817477_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_157470332.1\|817564_818182_-	DUF4406 domain-containing protein	A0A059PYA6	Anabaena_phage	2.4e-10	50.0
WP_082838481.1\|818364_819216_-	hypothetical protein	NA	NA	NA	NA
WP_082838482.1\|819300_819603_-	hypothetical protein	NA	NA	NA	NA
WP_082838483.1\|819605_821201_-	hypothetical protein	NA	NA	NA	NA
WP_082838484.1\|821273_822632_-	hypothetical protein	A0A1V0SDM6	Indivirus	1.9e-15	40.0
WP_082838485.1\|822633_823611_-	hypothetical protein	NA	NA	NA	NA
WP_082838486.1\|823610_824978_-	hypothetical protein	NA	NA	NA	NA
WP_082838487.1\|824977_825211_-	hypothetical protein	NA	NA	NA	NA
WP_082838488.1\|825258_825588_-	hypothetical protein	NA	NA	NA	NA
WP_082838489.1\|825641_826052_-	hypothetical protein	NA	NA	NA	NA
WP_082838490.1\|826078_826489_-	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_082838491.1\|826488_827034_-	hypothetical protein	NA	NA	NA	NA
WP_082838492.1\|827043_827391_-\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
WP_157469149.1\|827400_827541_-	hypothetical protein	NA	NA	NA	NA
WP_082838493.1\|827537_828104_-	hypothetical protein	NA	NA	NA	NA
WP_082838494.1\|828100_828418_-	hypothetical protein	NA	NA	NA	NA
WP_082838495.1\|828414_828906_-	hypothetical protein	NA	NA	NA	NA
WP_157469151.1\|828909_829368_-	hypothetical protein	NA	NA	NA	NA
WP_082838497.1\|829371_830742_-	hypothetical protein	NA	NA	NA	NA
WP_082838498.1\|830744_831122_-	hypothetical protein	NA	NA	NA	NA
WP_082838499.1\|831131_831410_-	hypothetical protein	NA	NA	NA	NA
WP_157469153.1\|831447_831777_-	hypothetical protein	NA	NA	NA	NA
WP_082838501.1\|831930_833319_-\|capsid	phage major capsid protein	A0A0F7L2V9	uncultured_marine_virus	2.0e-41	39.2
WP_157470335.1\|833433_834054_-\|head,protease	HK97 family phage prohead protease	A0A1J0GUZ0	Halomonas_phage	3.2e-23	50.4
WP_082838503.1\|834101_835394_-\|portal	phage portal protein	A0A2K5B287	Erysipelothrix_phage	2.4e-49	32.9

DBSCAN-SWA_2

1546820 : 1607654

Erythrobacter_phage(33.33%)

transposase,integrase

attL 1583160:1583177|attR 1607337:1607354

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162271616.1\|1546820_1547153_-\|transposase	transposase	NA	NA	NA	NA
WP_082838127.1\|1547588_1547990_+\|transposase	transposase	NA	NA	NA	NA
WP_082838126.1\|1548007_1548403_+	hypothetical protein	NA	NA	NA	NA
WP_082838925.1\|1548627_1551438_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_082838926.1\|1551723_1552020_+	hypothetical protein	NA	NA	NA	NA
WP_157469241.1\|1552183_1552357_+	hypothetical protein	NA	NA	NA	NA
WP_082838927.1\|1552663_1553641_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_082838928.1\|1553637_1554021_-	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_082838929.1\|1554013_1554265_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_082838930.1\|1554896_1555088_-	adhesin	NA	NA	NA	NA
WP_082838931.1\|1555113_1555647_-	hypothetical protein	NA	NA	NA	NA
WP_157469243.1\|1555686_1555863_+	hypothetical protein	NA	NA	NA	NA
WP_162271617.1\|1555892_1556327_-	PIN domain-containing protein	NA	NA	NA	NA
WP_162271618.1\|1556323_1556566_-	hypothetical protein	NA	NA	NA	NA
WP_082838933.1\|1556723_1557866_-	hypothetical protein	NA	NA	NA	NA
WP_082838934.1\|1557878_1567592_-	PKD domain-containing protein	NA	NA	NA	NA
WP_162271619.1\|1567615_1569475_-	hypothetical protein	NA	NA	NA	NA
WP_157469245.1\|1569621_1571538_-	FkbM family methyltransferase	NA	NA	NA	NA
WP_082838937.1\|1571546_1572317_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_082838938.1\|1572960_1573206_+	hypothetical protein	NA	NA	NA	NA
WP_157469247.1\|1573398_1573575_-	hypothetical protein	NA	NA	NA	NA
WP_082843228.1\|1573985_1574546_+	J domain-containing protein	A0A1P8VV96	Erythrobacter_phage	1.4e-30	40.6
WP_082838940.1\|1575236_1576811_+	relaxase domain-containing protein	NA	NA	NA	NA
WP_082838941.1\|1577841_1579107_+	AAA family ATPase	NA	NA	NA	NA
WP_082838942.1\|1579096_1579627_+	hypothetical protein	NA	NA	NA	NA
WP_157469249.1\|1579952_1581302_+	hypothetical protein	NA	NA	NA	NA
WP_162271620.1\|1581355_1582315_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_157469251.1\|1582384_1582855_+	hypothetical protein	NA	NA	NA	NA
WP_157470365.1\|1582859_1583941_-\|transposase	IS630 family transposase	NA	NA	NA	NA
1583160:1583177	attL	NA	NA	NA	NA
WP_162271621.1\|1584312_1584918_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_157469253.1\|1585134_1585980_+	hypothetical protein	NA	NA	NA	NA
WP_082838949.1\|1585997_1586180_+	hypothetical protein	NA	NA	NA	NA
WP_082838950.1\|1586388_1587498_+	hypothetical protein	NA	NA	NA	NA
WP_162271622.1\|1588119_1588938_+	ParB/RepB/Spo0J family partition protein	NA	NA	NA	NA
WP_082838952.1\|1588930_1590799_+	type IV secretory system conjugative DNA transfer family protein	NA	NA	NA	NA
WP_162271623.1\|1590802_1591075_+	hypothetical protein	NA	NA	NA	NA
WP_157469254.1\|1591103_1591280_+	hypothetical protein	NA	NA	NA	NA
WP_082838954.1\|1591477_1591666_+	hypothetical protein	NA	NA	NA	NA
WP_082838955.1\|1591655_1591853_+	hypothetical protein	NA	NA	NA	NA
WP_082838956.1\|1591901_1592111_+	hypothetical protein	NA	NA	NA	NA
WP_082838957.1\|1592127_1592520_+	hypothetical protein	NA	NA	NA	NA
WP_082838958.1\|1592566_1592731_+	DUF1232 domain-containing protein	NA	NA	NA	NA
WP_082838959.1\|1592877_1593135_+	hypothetical protein	NA	NA	NA	NA
WP_082838960.1\|1593303_1593537_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_082838961.1\|1593544_1594564_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_082838962.1\|1594676_1595150_-	hypothetical protein	NA	NA	NA	NA
WP_052560754.1\|1595437_1598119_+	pyruvate, phosphate dikinase	H8YJB7	Vibrio_phage	3.0e-86	39.3
WP_052560755.1\|1598328_1599150_+	hypothetical protein	NA	NA	NA	NA
WP_157470367.1\|1599224_1600124_+	hypothetical protein	NA	NA	NA	NA
WP_082838963.1\|1600231_1601704_-	RNA polymerase sigma factor	NA	NA	NA	NA
WP_082838964.1\|1601963_1603247_-	GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	2.5e-94	46.5
WP_052560759.1\|1603306_1604824_-	hypothetical protein	NA	NA	NA	NA
WP_082838965.1\|1605596_1605788_-	hypothetical protein	NA	NA	NA	NA
WP_082838966.1\|1606517_1607654_+\|transposase	IS630 family transposase	NA	NA	NA	NA
1607337:1607354	attR	NA	NA	NA	NA

DBSCAN-SWA_3

2137493 : 2145017

Arthrobacter_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_082839247.1\|2137493_2138354_+	hypothetical protein	V5R922	Arthrobacter_phage	1.5e-23	35.3
WP_082839248.1\|2138395_2139466_+	AAA family ATPase	A0A1W6JT44	Escherichia_phage	8.9e-29	31.0
WP_082839249.1\|2139501_2140764_+	AAA family ATPase	A0A286N2V7	Arthrobacter_phage	1.6e-53	35.6
WP_082839250.1\|2140793_2141762_+	YdaU family protein	A0A2H4J580	uncultured_Caudovirales_phage	1.1e-06	32.3
WP_082839251.1\|2141766_2142141_+	hypothetical protein	NA	NA	NA	NA
WP_157469334.1\|2142146_2142446_+	hypothetical protein	NA	NA	NA	NA
WP_082839253.1\|2142433_2143624_+	hypothetical protein	NA	NA	NA	NA
WP_082839254.1\|2143678_2143912_+	hypothetical protein	NA	NA	NA	NA
WP_082839255.1\|2143913_2144276_+	hypothetical protein	A0A1B1INM4	uncultured_Mediterranean_phage	6.9e-10	43.9
WP_082839256.1\|2144309_2145017_+	hypothetical protein	F8TV81	EBPR_siphovirus	8.4e-28	40.1

DBSCAN-SWA_4

2803130 : 2834573

Leptospira_phage(50.0%)

transposase,integrase

attL 2804857:2804916|attR 2829614:2831290

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_082839622.1\|2803130_2804438_+\|transposase	transposase	NA	NA	NA	NA
2804857:2804916	attL	NA	NA	NA	NA
WP_082839623.1\|2806603_2807665_+	hypothetical protein	NA	NA	NA	NA
WP_162271672.1\|2807770_2808118_+	hypothetical protein	NA	NA	NA	NA
WP_162271673.1\|2810059_2810470_+	hypothetical protein	NA	NA	NA	NA
WP_082839626.1\|2810505_2811180_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_082839628.1\|2811937_2813233_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_157469440.1\|2813464_2813761_+	DUF1580 domain-containing protein	NA	NA	NA	NA
WP_082839630.1\|2814156_2816946_+	hypothetical protein	NA	NA	NA	NA
WP_082839631.1\|2817339_2817696_+	hypothetical protein	NA	NA	NA	NA
WP_082839632.1\|2817771_2818173_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_082839633.1\|2818169_2818577_+	hypothetical protein	NA	NA	NA	NA
WP_082839634.1\|2818652_2818859_+	hypothetical protein	NA	NA	NA	NA
WP_082838827.1\|2818914_2819343_+	hypothetical protein	NA	NA	NA	NA
WP_082838828.1\|2819336_2819696_+	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	1.3e-13	33.0
WP_162271604.1\|2819743_2821264_+\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	1.1e-80	38.2
WP_157469441.1\|2821474_2822176_+	hypothetical protein	NA	NA	NA	NA
WP_082839636.1\|2822172_2822466_-	hypothetical protein	NA	NA	NA	NA
WP_082839637.1\|2822735_2822990_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_157469442.1\|2823145_2823319_+	hypothetical protein	NA	NA	NA	NA
WP_157469443.1\|2823442_2825371_-	hypothetical protein	NA	NA	NA	NA
WP_082839639.1\|2825433_2826798_+\|transposase	transposase	NA	NA	NA	NA
WP_082839640.1\|2827218_2827818_-	hypothetical protein	NA	NA	NA	NA
WP_082839641.1\|2829683_2829977_+	hypothetical protein	NA	NA	NA	NA
WP_082839642.1\|2830157_2830358_+	hypothetical protein	NA	NA	NA	NA
WP_082839643.1\|2830417_2830633_-	hypothetical protein	NA	NA	NA	NA
WP_082839644.1\|2830829_2831000_+	DUF1328 domain-containing protein	NA	NA	NA	NA
WP_082839645.1\|2831176_2833003_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
2829614:2831290	attR	NA	NA	NA	NA
WP_157470400.1\|2833615_2833867_+	hypothetical protein	NA	NA	NA	NA
WP_082838127.1\|2834171_2834573_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_5

3243571 : 3300323

Bordetella_phage(14.29%)

protease,portal,terminase,transposase,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_082839913.1\|3243571_3244216_+\|terminase	terminase small subunit	NA	NA	NA	NA
WP_082839914.1\|3244154_3245615_+	hypothetical protein	Q775B9	Bordetella_phage	4.8e-86	38.0
WP_082839915.1\|3245813_3246446_+	TIGR02996 domain-containing protein	NA	NA	NA	NA
WP_082839916.1\|3246484_3248998_+\|portal	phage portal protein	NA	NA	NA	NA
WP_082839917.1\|3249002_3249602_+	hypothetical protein	NA	NA	NA	NA
WP_082839918.1\|3249601_3253045_+	hypothetical protein	NA	NA	NA	NA
WP_082839919.1\|3253084_3253354_-	hypothetical protein	NA	NA	NA	NA
WP_082839302.1\|3253487_3253724_+	hypothetical protein	NA	NA	NA	NA
WP_082839301.1\|3253815_3253998_+	hypothetical protein	NA	NA	NA	NA
WP_157469354.1\|3254084_3254258_+	hypothetical protein	NA	NA	NA	NA
WP_082839300.1\|3254322_3254688_+	hypothetical protein	NA	NA	NA	NA
WP_082839299.1\|3254759_3254966_+	hypothetical protein	NA	NA	NA	NA
WP_082839920.1\|3255082_3256789_+	hypothetical protein	NA	NA	NA	NA
WP_082839921.1\|3256824_3258090_+\|capsid	phage major capsid protein	NA	NA	NA	NA
WP_082839922.1\|3258153_3258627_+	hypothetical protein	NA	NA	NA	NA
WP_082839923.1\|3258636_3258834_+	hypothetical protein	NA	NA	NA	NA
WP_082839924.1\|3258853_3259606_+	hypothetical protein	NA	NA	NA	NA
WP_082839925.1\|3259615_3259975_+	hypothetical protein	NA	NA	NA	NA
WP_082839926.1\|3260280_3260952_+	hypothetical protein	NA	NA	NA	NA
WP_082839927.1\|3260951_3261299_+	hypothetical protein	NA	NA	NA	NA
WP_157469487.1\|3261745_3262084_+	hypothetical protein	A0A292GJ83	Xanthomonas_phage	8.1e-13	38.6
WP_082839929.1\|3262397_3263384_-	hypothetical protein	A0A220IHA9	Escherichia_phage	1.1e-09	34.9
WP_082839930.1\|3264208_3264430_+	hypothetical protein	NA	NA	NA	NA
WP_082839931.1\|3264484_3264829_+	hypothetical protein	NA	NA	NA	NA
WP_082839932.1\|3265204_3265414_+	hypothetical protein	NA	NA	NA	NA
WP_082839933.1\|3265418_3266561_-	DUF2236 domain-containing protein	NA	NA	NA	NA
WP_082839934.1\|3266560_3267787_-	hypothetical protein	NA	NA	NA	NA
WP_082839935.1\|3267767_3268016_-	hypothetical protein	NA	NA	NA	NA
WP_082839936.1\|3268051_3268522_-	hypothetical protein	NA	NA	NA	NA
WP_082839937.1\|3268518_3268896_-	hypothetical protein	NA	NA	NA	NA
WP_082839938.1\|3268906_3269401_-	hypothetical protein	NA	NA	NA	NA
WP_082839939.1\|3269404_3269785_-	hypothetical protein	NA	NA	NA	NA
WP_082839940.1\|3269781_3270264_-	hypothetical protein	NA	NA	NA	NA
WP_157469488.1\|3270333_3271503_+	hypothetical protein	NA	NA	NA	NA
WP_082839942.1\|3271506_3271812_+	hypothetical protein	NA	NA	NA	NA
WP_082839943.1\|3271840_3272689_+	hypothetical protein	NA	NA	NA	NA
WP_082839944.1\|3272688_3277569_+	fibronectin type III domain-containing protein	NA	NA	NA	NA
WP_082839945.1\|3277573_3278647_+	hypothetical protein	NA	NA	NA	NA
WP_082839946.1\|3278636_3279212_-	hypothetical protein	NA	NA	NA	NA
WP_082839947.1\|3279447_3279780_+	hypothetical protein	NA	NA	NA	NA
WP_082839949.1\|3280396_3280987_+	hypothetical protein	NA	NA	NA	NA
WP_157469489.1\|3281059_3281206_+	hypothetical protein	NA	NA	NA	NA
WP_162271695.1\|3281275_3282130_+\|protease	matrixin family metalloprotease	W8W2D9	Invertebrate_iridovirus	4.8e-09	31.9
WP_157469490.1\|3282126_3282270_+	hypothetical protein	NA	NA	NA	NA
WP_082839951.1\|3282266_3282446_+	hypothetical protein	NA	NA	NA	NA
WP_082839952.1\|3282446_3283970_+	hypothetical protein	NA	NA	NA	NA
WP_082839953.1\|3283966_3284569_+	hypothetical protein	NA	NA	NA	NA
WP_082839954.1\|3284599_3285019_+	hypothetical protein	NA	NA	NA	NA
WP_082839955.1\|3285172_3285493_+	hypothetical protein	NA	NA	NA	NA
WP_082839956.1\|3285501_3285897_+	hypothetical protein	NA	NA	NA	NA
WP_082839957.1\|3285889_3286120_+	hypothetical protein	NA	NA	NA	NA
WP_052558149.1\|3286648_3286867_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_052558147.1\|3287376_3287865_+	hypothetical protein	NA	NA	NA	NA
WP_082839958.1\|3287893_3290671_-	serine/threonine-protein kinase	A0A1V0SDC3	Indivirus	5.7e-11	31.1
WP_082839959.1\|3290765_3292661_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_082839960.1\|3293054_3295643_+	PAS domain S-box protein	Q8QKV4	Ectocarpus_siliculosus_virus	1.0e-09	23.4
WP_082839961.1\|3295797_3296739_-	cysteine synthase A	A0A1X9I5K7	Streptococcus_phage	2.8e-79	51.3
WP_082839962.1\|3296754_3297219_-	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_157469491.1\|3298942_3299092_+	hypothetical protein	NA	NA	NA	NA
WP_162271696.1\|3299549_3300323_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_6

3643685 : 3692497

Pandoravirus(16.67%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_052557623.1\|3643685_3645767_+\|protease	serine protease	NA	NA	NA	NA
WP_157469515.1\|3645819_3645978_+	hypothetical protein	NA	NA	NA	NA
WP_162271717.1\|3646015_3646408_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_082840152.1\|3646442_3647561_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_052557619.1\|3647869_3648400_-	hypothetical protein	NA	NA	NA	NA
WP_082840154.1\|3649325_3649685_-	hypothetical protein	NA	NA	NA	NA
WP_082839812.1\|3649728_3650649_-\|transposase	transposase	NA	NA	NA	NA
WP_052557614.1\|3650959_3651397_-	DUF2784 family protein	NA	NA	NA	NA
WP_082840155.1\|3651613_3653038_-	serine/threonine protein kinase	S4VR00	Pandoravirus	2.3e-24	33.1
WP_162271718.1\|3653340_3656544_+	c-type cytochrome	NA	NA	NA	NA
WP_082840157.1\|3656547_3657009_+	hypothetical protein	NA	NA	NA	NA
WP_082840158.1\|3657088_3657640_+	hypothetical protein	NA	NA	NA	NA
WP_082840159.1\|3657746_3659093_-\|protease	ATP-dependent protease ATPase subunit HslU	A0A191ZC11	Erwinia_phage	5.5e-36	25.0
WP_082840160.1\|3659241_3659778_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_082840161.1\|3659983_3660562_+	hypothetical protein	NA	NA	NA	NA
WP_157469516.1\|3660631_3661717_+	hypothetical protein	NA	NA	NA	NA
WP_082840162.1\|3661804_3662284_+	HIT family protein	NA	NA	NA	NA
WP_082840163.1\|3662280_3663192_+	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_082840164.1\|3663334_3666700_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_082840165.1\|3667153_3667777_+	DedA family protein	NA	NA	NA	NA
WP_157470421.1\|3668230_3668515_+	hypothetical protein	NA	NA	NA	NA
WP_082843304.1\|3668816_3670346_+	OFA family MFS transporter	NA	NA	NA	NA
WP_157469517.1\|3670357_3671191_-	hypothetical protein	NA	NA	NA	NA
WP_157469518.1\|3671242_3671443_-	hypothetical protein	NA	NA	NA	NA
WP_082840167.1\|3671396_3672689_-	AI-2E family transporter	NA	NA	NA	NA
WP_082840168.1\|3672742_3673618_-	bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	2.5e-29	34.3
WP_082840169.1\|3673625_3674384_-	NAD-dependent deacylase	A0A1C3S788	Escherichia_phage	1.9e-17	26.7
WP_052558871.1\|3674533_3675337_-	inositol monophosphatase	NA	NA	NA	NA
WP_052557576.1\|3675586_3677812_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	4.5e-19	23.9
WP_052557574.1\|3677977_3679270_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_052557572.1\|3679440_3680934_-	hypothetical protein	NA	NA	NA	NA
WP_157469519.1\|3681042_3681192_+	hypothetical protein	NA	NA	NA	NA
WP_052557570.1\|3681384_3682398_+	hypothetical protein	NA	NA	NA	NA
WP_157469520.1\|3682675_3684004_+	phosphomethylpyrimidine synthase ThiC	NA	NA	NA	NA
WP_082840171.1\|3684415_3685606_+	hypothetical protein	NA	NA	NA	NA
WP_157469521.1\|3686060_3688313_+	hypothetical protein	A0A2K9L1M9	Tupanvirus	2.1e-08	49.5
WP_082840173.1\|3688399_3689071_+	hypothetical protein	NA	NA	NA	NA
WP_082840174.1\|3689332_3691270_-	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_082840175.1\|3691378_3692497_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_7

3845680 : 3955298

uncultured_Mediterranean_phage(33.33%)

transposase,integrase,portal

attL 3914534:3914557|attR 3958175:3958192

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_082840246.1\|3845680_3846196_+\|transposase	transposase	NA	NA	NA	NA
WP_157469536.1\|3846730_3846892_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_052555661.1\|3847165_3849859_+	DUF1549 domain-containing protein	NA	NA	NA	NA
WP_052555277.1\|3849963_3850272_+	hypothetical protein	NA	NA	NA	NA
WP_082840248.1\|3850321_3850792_-	DUF664 domain-containing protein	NA	NA	NA	NA
WP_157469537.1\|3850982_3851396_+	hypothetical protein	NA	NA	NA	NA
WP_082840249.1\|3852323_3853670_-	DUF1552 domain-containing protein	NA	NA	NA	NA
WP_082840250.1\|3853840_3856243_-	DUF1592 domain-containing protein	NA	NA	NA	NA
WP_052555285.1\|3856490_3857648_-	glycosyltransferase	NA	NA	NA	NA
WP_082840251.1\|3857663_3858803_-	glycosyltransferase	NA	NA	NA	NA
WP_052555288.1\|3858946_3859390_-	EamA family transporter	NA	NA	NA	NA
WP_082840252.1\|3859389_3861138_-	hypothetical protein	NA	NA	NA	NA
WP_052555663.1\|3861162_3861846_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_082840253.1\|3861936_3863061_-	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	NA	NA	NA	NA
WP_082840254.1\|3863478_3864765_-	hypothetical protein	NA	NA	NA	NA
WP_082840255.1\|3864895_3865360_-	hypothetical protein	NA	NA	NA	NA
WP_082840256.1\|3865533_3866457_-	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_082840257.1\|3866580_3868197_-	NAD(P)-binding protein	NA	NA	NA	NA
WP_082840258.1\|3868395_3871635_+	DUF1553 domain-containing protein	NA	NA	NA	NA
WP_082840259.1\|3871725_3873210_+	DUF1501 domain-containing protein	NA	NA	NA	NA
WP_082840260.1\|3873453_3874722_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_082840261.1\|3874801_3875071_-	acylphosphatase	NA	NA	NA	NA
WP_082840262.1\|3875293_3876811_+	4-alpha-glucanotransferase	NA	NA	NA	NA
WP_052555307.1\|3876814_3877027_-	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_082843319.1\|3877044_3878904_-	molecular chaperone DnaK	F2Y2E1	Organic_Lake_phycodnavirus	3.0e-109	39.7
WP_052555313.1\|3879079_3879757_-	DUF4282 domain-containing protein	NA	NA	NA	NA
WP_052555315.1\|3879870_3880173_-	alkylhydroperoxidase	NA	NA	NA	NA
WP_082840263.1\|3880185_3880707_-	Fe-S protein assembly co-chaperone HscB	NA	NA	NA	NA
WP_082840264.1\|3880754_3881168_-	iron-sulfur cluster assembly accessory protein	A0A1B1IT29	uncultured_Mediterranean_phage	2.8e-15	38.4
WP_052555321.1\|3881243_3881669_-	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	7.5e-48	76.0
WP_052555323.1\|3881719_3882937_-	IscS subfamily cysteine desulfurase	H7BUW1	unidentified_phage	1.2e-37	39.5
WP_052555325.1\|3883044_3883542_-	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_082843320.1\|3883713_3884562_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_082843311.1\|3886051_3886840_+\|transposase	transposase	NA	NA	NA	NA
WP_052555334.1\|3887053_3887656_+	hypothetical protein	NA	NA	NA	NA
WP_052555336.1\|3887652_3888009_+	hypothetical protein	NA	NA	NA	NA
WP_052555337.1\|3888005_3888692_+	hypothetical protein	NA	NA	NA	NA
WP_052555338.1\|3888789_3890037_+	hypothetical protein	NA	NA	NA	NA
WP_082840265.1\|3890100_3892059_+	ATP-binding protein	NA	NA	NA	NA
WP_082840266.1\|3892063_3892423_-	DUF5615 family PIN-like protein	NA	NA	NA	NA
WP_082840267.1\|3892419_3892656_-	DUF433 domain-containing protein	NA	NA	NA	NA
WP_082840268.1\|3892793_3893012_+	hypothetical protein	NA	NA	NA	NA
WP_082840269.1\|3893042_3894752_+	CRISPR-associated endonuclease Cas4/Cas1	NA	NA	NA	NA
WP_052555344.1\|3895124_3895409_+	CRISPR-associated endonuclease Cas2	NA	NA	NA	NA
WP_082840270.1\|3895421_3897680_+	type I-U CRISPR-associated helicase/endonuclease Cas3	NA	NA	NA	NA
WP_082838323.1\|3897685_3898972_-\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_162271723.1\|3899891_3900479_+	hypothetical protein	NA	NA	NA	NA
WP_082840271.1\|3900471_3901569_+	type I-U CRISPR-associated protein Cas7	NA	NA	NA	NA
WP_082840272.1\|3901581_3903237_+	type I-U CRISPR-associated protein Cas5/Cas6	NA	NA	NA	NA
WP_082840273.1\|3912209_3912431_-	hypothetical protein	NA	NA	NA	NA
WP_082839639.1\|3912452_3913817_-\|transposase	transposase	NA	NA	NA	NA
WP_162271724.1\|3913846_3914212_-	hypothetical protein	NA	NA	NA	NA
3914534:3914557	attL	NA	NA	NA	NA
WP_082840275.1\|3914869_3916111_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
3914534:3914557	attL	NA	NA	NA	NA
WP_162271725.1\|3916381_3916888_-\|transposase	transposase	NA	NA	NA	NA
WP_162271725.1\|3916381_3916888_-\|transposase	transposase	NA	NA	NA	NA
3916308:3916331	attR	NA	NA	NA	NA
WP_157469540.1\|3916932_3917418_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
3916308:3916331	attR	NA	NA	NA	NA
WP_052554838.1\|3917414_3918089_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_082840278.1\|3918127_3918682_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_082838128.1\|3918818_3920156_+	hypothetical protein	NA	NA	NA	NA
WP_082843321.1\|3920480_3921269_-\|transposase	transposase	NA	NA	NA	NA
WP_157469541.1\|3921396_3921639_+	hypothetical protein	NA	NA	NA	NA
WP_082840280.1\|3921719_3921914_-	hypothetical protein	NA	NA	NA	NA
WP_082840281.1\|3921910_3922453_-\|transposase	IS1595 family transposase	NA	NA	NA	NA
WP_157469542.1\|3922397_3922853_-	hypothetical protein	NA	NA	NA	NA
WP_082840283.1\|3923361_3923526_+	hypothetical protein	NA	NA	NA	NA
WP_162271726.1\|3923546_3923771_-	hypothetical protein	NA	NA	NA	NA
WP_082840285.1\|3924095_3925391_-\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_052561678.1\|3925593_3925773_-	hypothetical protein	NA	NA	NA	NA
WP_082840286.1\|3925779_3928305_-	PAS domain-containing protein	B5LWA6	Feldmannia_species_virus	4.5e-07	26.0
WP_162271727.1\|3928449_3928842_-	response regulator	NA	NA	NA	NA
WP_052561684.1\|3929191_3929491_-	hypothetical protein	NA	NA	NA	NA
WP_082840287.1\|3929671_3930577_-	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_082840288.1\|3930825_3932520_-	AarF/ABC1/UbiB kinase family protein	A9YVW0	Ostreococcus_tauri_virus	5.5e-33	26.6
WP_082840289.1\|3932648_3933404_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_082840290.1\|3933567_3934827_+	hypothetical protein	NA	NA	NA	NA
WP_082840291.1\|3934926_3935979_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_052561696.1\|3936185_3936530_+	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_052561698.1\|3936604_3937129_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_162271728.1\|3937293_3937587_+	HPr family phosphocarrier protein	NA	NA	NA	NA
WP_052561702.1\|3937672_3939463_+	phosphoenolpyruvate--protein phosphotransferase	NA	NA	NA	NA
WP_082840293.1\|3939832_3940534_+	DUF2344 domain-containing protein	NA	NA	NA	NA
WP_052561706.1\|3940527_3940836_+	hypothetical protein	NA	NA	NA	NA
WP_157470427.1\|3941964_3943818_+	Rne/Rng family ribonuclease	NA	NA	NA	NA
WP_082840295.1\|3943877_3944486_+	hypothetical protein	NA	NA	NA	NA
WP_052561713.1\|3944531_3945590_+	selenide, water dikinase SelD	NA	NA	NA	NA
WP_082840296.1\|3945617_3946994_+	sulfatase	NA	NA	NA	NA
WP_082840297.1\|3947277_3948465_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_082840298.1\|3948820_3949243_+	hypothetical protein	NA	NA	NA	NA
WP_082840299.1\|3949287_3949719_+	hypothetical protein	NA	NA	NA	NA
WP_082840300.1\|3949715_3950981_+	AAA family ATPase	Q9JMN6	Wolbachia_phage	1.3e-07	24.8
WP_082840301.1\|3951223_3951955_+	hypothetical protein	NA	NA	NA	NA
WP_157469544.1\|3952264_3953716_+	hypothetical protein	A0A1B1IPV3	uncultured_Mediterranean_phage	2.9e-38	28.6
WP_082840304.1\|3953789_3955298_+\|portal	phage portal protein	A0A1B1IPT4	uncultured_Mediterranean_phage	2.1e-31	28.5
3958175:3958192	attR	NA	NA	NA	NA

DBSCAN-SWA_8

4073065 : 4147489

uncultured_Mediterranean_phage(14.29%)

transposase,integrase,tRNA

attL 4076172:4076189|attR 4160027:4160044

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157470429.1\|4073065_4073785_-\|transposase	transposase	NA	NA	NA	NA
WP_082840371.1\|4074398_4075778_+\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_052561858.1\|4076043_4076298_+	hypothetical protein	NA	NA	NA	NA
4076172:4076189	attL	NA	NA	NA	NA
WP_082840372.1\|4078178_4079036_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
4076172:4076189	attL	NA	NA	NA	NA
WP_082840373.1\|4079401_4080592_-\|integrase	site-specific integrase	A0A1B1IUW9	uncultured_Mediterranean_phage	1.7e-33	29.7
WP_162271732.1\|4081111_4081711_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_162271733.1\|4081692_4081902_+\|transposase	transposase	NA	NA	NA	NA
WP_157469554.1\|4081905_4082079_-	hypothetical protein	NA	NA	NA	NA
WP_082840375.1\|4082217_4082553_-	hypothetical protein	NA	NA	NA	NA
WP_082840376.1\|4082515_4083145_-	response regulator	A0A2K9L0Z8	Tupanvirus	3.1e-05	39.1
WP_157469556.1\|4083053_4083887_-	PAS domain S-box protein	NA	NA	NA	NA
WP_162271734.1\|4083913_4084621_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_157469557.1\|4084698_4086081_-\|transposase	ISKra4 family transposase	NA	NA	NA	NA
WP_162271735.1\|4086928_4087147_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_082843330.1\|4087865_4088429_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_162271736.1\|4088511_4089039_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_157469560.1\|4089022_4089541_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_162271737.1\|4090639_4091437_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_082838127.1\|4091473_4091875_-\|transposase	transposase	NA	NA	NA	NA
WP_082840381.1\|4092112_4093102_-\|transposase	transposase	NA	NA	NA	NA
WP_162271738.1\|4093569_4094967_+	TolC family protein	NA	NA	NA	NA
4094599:4094616	attR	NA	NA	NA	NA
WP_082840383.1\|4095031_4098301_+	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	3.3e-58	22.8
4094599:4094616	attR	NA	NA	NA	NA
WP_082840384.1\|4098290_4099637_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_052553883.1\|4100221_4100440_+	hypothetical protein	NA	NA	NA	NA
WP_082840385.1\|4100463_4101546_-	PA0069 family radical SAM protein	NA	NA	NA	NA
WP_082840386.1\|4101754_4102714_+	hypothetical protein	NA	NA	NA	NA
WP_082840387.1\|4102714_4103038_+	hypothetical protein	NA	NA	NA	NA
WP_052553892.1\|4103103_4103508_+	DoxX family membrane protein	NA	NA	NA	NA
WP_082840388.1\|4103522_4104560_+	hypothetical protein	NA	NA	NA	NA
WP_157469561.1\|4104635_4104881_-	hypothetical protein	NA	NA	NA	NA
WP_052553901.1\|4104961_4106209_-	MFS transporter	NA	NA	NA	NA
WP_082840389.1\|4106350_4107370_+	decarboxylating 6-phosphogluconate dehydrogenase	M1T2E7	Synechococcus_phage	1.0e-90	53.3
WP_052553907.1\|4107422_4107701_-	hypothetical protein	NA	NA	NA	NA
WP_052553909.1\|4107697_4108942_-	hypothetical protein	NA	NA	NA	NA
WP_082840390.1\|4110560_4111364_-	PhzF family phenazine biosynthesis protein	NA	NA	NA	NA
WP_082840391.1\|4111431_4114479_+	c-type cytochrome	NA	NA	NA	NA
WP_082843331.1\|4114655_4115444_-\|transposase	transposase	NA	NA	NA	NA
WP_157469562.1\|4115768_4115939_-	hypothetical protein	NA	NA	NA	NA
WP_082839639.1\|4117056_4118421_+\|transposase	transposase	NA	NA	NA	NA
WP_157469563.1\|4119515_4119713_+	hypothetical protein	NA	NA	NA	NA
WP_052553915.1\|4119766_4121389_-	protein kinase	L7RGQ5	Acanthamoeba_polyphaga_moumouvirus	1.8e-17	28.3
WP_082840394.1\|4121489_4121951_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_157469564.1\|4122061_4123187_-	peptide chain release factor 2	NA	NA	NA	NA
WP_052555590.1\|4123330_4124065_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	1.2e-08	28.2
WP_082840395.1\|4124120_4126046_-	hypothetical protein	NA	NA	NA	NA
WP_082840396.1\|4126440_4130220_-	c-type cytochrome	NA	NA	NA	NA
WP_052553927.1\|4130381_4131347_-	PDZ domain-containing protein	NA	NA	NA	NA
WP_052553929.1\|4131586_4132165_-	hypothetical protein	NA	NA	NA	NA
WP_082840398.1\|4132532_4133537_-	NAD(P)-dependent alcohol dehydrogenase	NA	NA	NA	NA
WP_157469565.1\|4133731_4137019_+	protein kinase	A0A160EPW9	Powai_lake_megavirus	4.5e-15	25.2
WP_052553935.1\|4137288_4139307_-	amino acid transporter	NA	NA	NA	NA
WP_082840400.1\|4139502_4139913_-	DUF4112 domain-containing protein	NA	NA	NA	NA
WP_162271739.1\|4139984_4140839_-	exo-alpha-sialidase	NA	NA	NA	NA
WP_052553941.1\|4140923_4141394_-	TIGR02996 domain-containing protein	NA	NA	NA	NA
WP_082840403.1\|4141399_4142635_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_052553945.1\|4143331_4143760_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_052553946.1\|4143863_4144295_-	hypothetical protein	NA	NA	NA	NA
WP_052553949.1\|4144524_4145298_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_082840404.1\|4145524_4146433_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_082840405.1\|4146472_4147489_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
4160027:4160044	attR	NA	NA	NA	NA

DBSCAN-SWA_9

4735828 : 4831492

Paenibacillus_phage(25.0%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157469641.1\|4735828_4736209_+\|transposase	transposase	NA	NA	NA	NA
WP_052554143.1\|4737469_4737991_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_082839376.1\|4738020_4738575_+	hypothetical protein	NA	NA	NA	NA
WP_082840699.1\|4738590_4739139_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_052554770.1\|4739164_4739719_-	hypothetical protein	NA	NA	NA	NA
WP_052554773.1\|4739735_4740227_-	hypothetical protein	NA	NA	NA	NA
WP_052554775.1\|4740255_4741008_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_162271776.1\|4741101_4741830_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_082843204.1\|4741819_4742521_-	hypothetical protein	NA	NA	NA	NA
WP_082840702.1\|4743742_4746595_+	DUF1553 domain-containing protein	NA	NA	NA	NA
WP_082840703.1\|4746656_4748081_+	DUF1501 domain-containing protein	NA	NA	NA	NA
WP_052554785.1\|4748091_4748910_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_052554786.1\|4749134_4750010_-	3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase	NA	NA	NA	NA
WP_082840704.1\|4750092_4751922_+	squalene--hopene cyclase	NA	NA	NA	NA
WP_052554790.1\|4751992_4752955_-	thioesterase	NA	NA	NA	NA
WP_082840705.1\|4753175_4754975_+	DUF116 domain-containing protein	NA	NA	NA	NA
WP_082840706.1\|4755127_4755676_+	hypothetical protein	NA	NA	NA	NA
WP_157469643.1\|4755738_4755945_-	hypothetical protein	NA	NA	NA	NA
WP_082840708.1\|4756120_4756513_+	hypothetical protein	NA	NA	NA	NA
WP_082840709.1\|4756618_4757602_+\|transposase	IS256 family transposase	A0A0K2CZ57	Paenibacillus_phage	1.6e-32	29.2
WP_052554802.1\|4758350_4759439_-	hypothetical protein	NA	NA	NA	NA
WP_052554804.1\|4759481_4760495_-	hypothetical protein	NA	NA	NA	NA
WP_082840710.1\|4760699_4764056_+	hypothetical protein	NA	NA	NA	NA
WP_082840711.1\|4764145_4765588_+	serine/threonine protein kinase	NA	NA	NA	NA
WP_052554810.1\|4765597_4766419_+	sugar phosphate isomerase/epimerase	NA	NA	NA	NA
WP_082840712.1\|4766570_4767353_+	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	1.7e-45	42.5
WP_082840713.1\|4767398_4769183_-	DUF2029 domain-containing protein	NA	NA	NA	NA
WP_052554816.1\|4769221_4770082_-	diaminopimelate epimerase	NA	NA	NA	NA
WP_082840714.1\|4770192_4770504_+	hypothetical protein	NA	NA	NA	NA
WP_052554820.1\|4770543_4771671_-	pseudouridine synthase	NA	NA	NA	NA
WP_082840715.1\|4771884_4772586_+	hypothetical protein	NA	NA	NA	NA
WP_052554824.1\|4772708_4773695_-	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_052554826.1\|4773741_4774377_-	hypothetical protein	NA	NA	NA	NA
WP_082840716.1\|4774394_4775411_-	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_052554829.1\|4775991_4777581_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_157469645.1\|4777749_4778172_-	hypothetical protein	NA	NA	NA	NA
WP_162271777.1\|4778188_4778665_-\|transposase	transposase	NA	NA	NA	NA
WP_162271778.1\|4779119_4780448_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_162271725.1\|4780649_4781156_-\|transposase	transposase	NA	NA	NA	NA
WP_157469540.1\|4781200_4781686_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_052554838.1\|4781682_4782357_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_082840278.1\|4782395_4782950_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_162271779.1\|4783212_4783917_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_082840721.1\|4783670_4784150_-	hypothetical protein	NA	NA	NA	NA
WP_157469649.1\|4784927_4785206_+	hypothetical protein	NA	NA	NA	NA
WP_157469651.1\|4786003_4786156_+	hypothetical protein	NA	NA	NA	NA
WP_052555019.1\|4786213_4786474_-	hypothetical protein	NA	NA	NA	NA
WP_082840722.1\|4786836_4788705_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	3.1e-101	35.6
WP_082840723.1\|4788887_4789241_+	cupin domain-containing protein	NA	NA	NA	NA
WP_082840724.1\|4789400_4794398_+	VWA domain-containing protein	NA	NA	NA	NA
WP_082840725.1\|4794479_4798526_+	hypothetical protein	NA	NA	NA	NA
WP_082840726.1\|4798566_4799424_+	hypothetical protein	NA	NA	NA	NA
WP_052555030.1\|4799504_4800653_+	twin-arginine translocation signal domain-containing protein	NA	NA	NA	NA
WP_082840727.1\|4800842_4802519_+	hypothetical protein	NA	NA	NA	NA
WP_082840728.1\|4802594_4803074_+	hypothetical protein	NA	NA	NA	NA
WP_082840729.1\|4803168_4804044_+	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_082840730.1\|4804040_4804838_+	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_052555039.1\|4804981_4806265_+	AMP-binding protein	NA	NA	NA	NA
WP_082840731.1\|4806413_4807598_+	hypothetical protein	NA	NA	NA	NA
WP_082838126.1\|4807667_4808063_-	hypothetical protein	NA	NA	NA	NA
WP_082838127.1\|4808080_4808482_-\|transposase	transposase	NA	NA	NA	NA
WP_157469653.1\|4808549_4808720_-	hypothetical protein	NA	NA	NA	NA
WP_082840732.1\|4808775_4809654_-	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_082840733.1\|4810043_4811480_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_082840734.1\|4811406_4812606_+	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_082840735.1\|4812623_4813736_+	PQQ-binding-like beta-propeller repeat protein	NA	NA	NA	NA
WP_052555050.1\|4813756_4814542_+	transcriptional regulator	NA	NA	NA	NA
WP_082840736.1\|4814556_4815882_+	coproporphyrinogen III oxidase family protein	NA	NA	NA	NA
WP_082840737.1\|4816094_4816559_+	glycine cleavage system protein H	NA	NA	NA	NA
WP_082840738.1\|4816623_4818897_+	NYN domain-containing protein	NA	NA	NA	NA
WP_052555057.1\|4818893_4819946_+	ferredoxin family protein	NA	NA	NA	NA
WP_052555060.1\|4819986_4820937_+	HDOD domain-containing protein	NA	NA	NA	NA
WP_052555062.1\|4821133_4821604_+	hypothetical protein	NA	NA	NA	NA
WP_052555064.1\|4822372_4823452_+	terpene cyclase/mutase family protein	NA	NA	NA	NA
WP_052555646.1\|4823703_4824426_+	1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase	NA	NA	NA	NA
WP_052555066.1\|4824482_4826627_+	elongation factor G	E4ZFJ7	Streptococcus_phage	1.7e-47	24.4
WP_052555069.1\|4826793_4827522_+	MotA/TolQ/ExbB proton channel family protein	NA	NA	NA	NA
WP_052555071.1\|4827647_4828427_+	biopolymer transporter ExbD	NA	NA	NA	NA
WP_052555073.1\|4828423_4829041_+	hypothetical protein	NA	NA	NA	NA
WP_082840740.1\|4829219_4830674_+	HD domain-containing protein	NA	NA	NA	NA
WP_052555648.1\|4830775_4831492_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_10

5904981 : 5915944

Stx2-converting_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157469788.1\|5904981_5906119_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_082841313.1\|5906217_5907336_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_157469790.1\|5907415_5907505_+	hypothetical protein	NA	NA	NA	NA
WP_082841314.1\|5907637_5908828_-\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	9.1e-59	37.3
WP_082841315.1\|5908840_5909185_-	hypothetical protein	NA	NA	NA	NA
WP_082841316.1\|5909230_5909545_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	1.0e-17	50.5
WP_052560408.1\|5909586_5909964_-	hypothetical protein	NA	NA	NA	NA
WP_082841317.1\|5910156_5911272_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_082841318.1\|5911301_5911613_+\|transposase	transposase	NA	NA	NA	NA
WP_052560406.1\|5911659_5914410_-	hypothetical protein	NA	NA	NA	NA
WP_082841319.1\|5915164_5915944_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_11

6883595 : 6957457

Bacillus_phage(20.0%)

protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_082843435.1\|6883595_6884534_+\|tRNA	tRNA-dihydrouridine synthase family protein	NA	NA	NA	NA
WP_082841869.1\|6884535_6888279_-	PAS domain S-box protein	NA	NA	NA	NA
WP_082841870.1\|6888659_6889286_-	FMN-binding negative transcriptional regulator	NA	NA	NA	NA
WP_157469903.1\|6889528_6889690_+	hypothetical protein	NA	NA	NA	NA
WP_052556163.1\|6889829_6890033_+	hypothetical protein	NA	NA	NA	NA
WP_082841872.1\|6890381_6891515_-	terpene cyclase/mutase family protein	NA	NA	NA	NA
WP_082841873.1\|6891717_6895803_-	DUF1080 domain-containing protein	NA	NA	NA	NA
WP_082841874.1\|6896042_6896384_+	hypothetical protein	NA	NA	NA	NA
WP_082841875.1\|6896425_6896986_+	hypothetical protein	NA	NA	NA	NA
WP_082841876.1\|6897190_6898615_+	dihydrolipoyl dehydrogenase	NA	NA	NA	NA
WP_082841877.1\|6898716_6900162_+	hypothetical protein	NA	NA	NA	NA
WP_082841878.1\|6900205_6901528_-	MFS transporter	NA	NA	NA	NA
WP_082841879.1\|6901761_6902028_+	hypothetical protein	NA	NA	NA	NA
WP_082841880.1\|6902277_6903120_-	hypothetical protein	NA	NA	NA	NA
WP_052556180.1\|6903193_6904723_-	Hsp70 family protein	A0A0N9QXN8	Chrysochromulina_ericina_virus	4.3e-69	35.8
WP_082841881.1\|6904866_6905688_+	hypothetical protein	NA	NA	NA	NA
WP_082841882.1\|6905742_6906033_-	hypothetical protein	NA	NA	NA	NA
WP_157469905.1\|6906223_6906445_+	hypothetical protein	NA	NA	NA	NA
WP_082841883.1\|6906569_6908516_-	response regulator	B5LWN8	Feldmannia_species_virus	7.3e-05	35.1
WP_052556187.1\|6908532_6908994_-	response regulator	NA	NA	NA	NA
WP_082841884.1\|6909377_6911564_-	PAS domain-containing protein	W8CYF6	Bacillus_phage	1.5e-14	29.9
WP_157469907.1\|6911635_6913765_-	PAS domain-containing protein	W8CYF6	Bacillus_phage	3.0e-12	29.3
WP_082841886.1\|6914322_6914898_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_082841887.1\|6914884_6917083_+	serine/threonine protein kinase	A0A0G2YB36	Acanthamoeba_polyphaga_mimivirus	1.8e-12	31.3
WP_162271876.1\|6917243_6918569_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_082841889.1\|6918599_6921965_+	multidrug efflux RND transporter permease subunit	NA	NA	NA	NA
WP_082841890.1\|6921965_6925328_+	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	1.6e-47	20.6
WP_082841891.1\|6925405_6926518_+	DUF3500 domain-containing protein	NA	NA	NA	NA
WP_082841892.1\|6926553_6927390_-	methylated-DNA--[protein]-cysteine S-methyltransferase	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	2.5e-18	46.7
WP_082841893.1\|6927621_6929409_-	PQQ-like beta-propeller repeat protein	NA	NA	NA	NA
WP_082841894.1\|6929548_6930061_-	nucleoside deaminase	NA	NA	NA	NA
WP_082841895.1\|6930159_6932334_-	hypothetical protein	NA	NA	NA	NA
WP_082841896.1\|6932392_6933118_-	DUF1669 domain-containing protein	NA	NA	NA	NA
WP_082841897.1\|6933187_6933619_-	TIGR03067 domain-containing protein	NA	NA	NA	NA
WP_162271877.1\|6933665_6934703_-	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_082841899.1\|6934822_6935302_-	cyclic pyranopterin monophosphate synthase MoaC	NA	NA	NA	NA
WP_082841900.1\|6935362_6936256_-	hypothetical protein	NA	NA	NA	NA
WP_082841901.1\|6936359_6936977_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	2.8e-51	53.2
WP_082843436.1\|6937215_6937842_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	1.8e-34	42.4
WP_157469909.1\|6937977_6939507_-	trigger factor	NA	NA	NA	NA
WP_082841903.1\|6940571_6941420_-	hypothetical protein	NA	NA	NA	NA
WP_052556222.1\|6942020_6942626_+	flavin reductase family protein	NA	NA	NA	NA
WP_052556224.1\|6942638_6943253_-	hypothetical protein	NA	NA	NA	NA
WP_157469911.1\|6943791_6944172_+	hypothetical protein	NA	NA	NA	NA
WP_052556228.1\|6944212_6944755_+	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_082843437.1\|6946250_6946685_+	DUF1810 domain-containing protein	A0A2H4UVK5	Bodo_saltans_virus	1.7e-15	41.5
WP_082841905.1\|6946786_6948292_-	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_052556233.1\|6948454_6949660_+	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	NA	NA	NA	NA
WP_082841906.1\|6949661_6950702_+	DUF1963 domain-containing protein	NA	NA	NA	NA
WP_157469913.1\|6951233_6951434_+	hypothetical protein	NA	NA	NA	NA
WP_052556239.1\|6951447_6951720_+	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_162271878.1\|6951653_6952130_+	hypothetical protein	NA	NA	NA	NA
WP_082841909.1\|6952853_6953900_-	hypothetical protein	NA	NA	NA	NA
WP_082839551.1\|6953896_6954154_-	hypothetical protein	NA	NA	NA	NA
WP_052557863.1\|6954307_6954985_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_157469919.1\|6954896_6955460_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_082841911.1\|6955835_6956054_+	hypothetical protein	NA	NA	NA	NA
WP_082841912.1\|6956333_6956729_-\|transposase	transposase	NA	NA	NA	NA
WP_157469924.1\|6956755_6957013_-	hypothetical protein	NA	NA	NA	NA
WP_162271879.1\|6957022_6957457_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_12

7288736 : 7329937

Pandoravirus(25.0%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_052556744.1\|7288736_7289198_-\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_052556746.1\|7289314_7289956_-	TIGR02996 domain-containing protein	NA	NA	NA	NA
WP_082842130.1\|7290102_7291263_+	cystathionine gamma-synthase	A0A0B5JD48	Pandoravirus	2.2e-25	32.4
WP_082842131.1\|7291337_7292411_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_052556751.1\|7292389_7293040_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_052556753.1\|7293036_7295157_-	molybdopterin oxidoreductase family protein	A0A077SK27	Escherichia_phage	2.3e-44	28.1
WP_052556755.1\|7295962_7296148_+	hypothetical protein	NA	NA	NA	NA
WP_052556757.1\|7296394_7297204_-	DUF1275 domain-containing protein	NA	NA	NA	NA
WP_052556758.1\|7297543_7298044_-	universal stress protein	NA	NA	NA	NA
WP_052556762.1\|7299097_7300687_+	serine/threonine protein kinase	M1PWP3	Moumouvirus	2.2e-20	30.5
WP_082842134.1\|7300847_7303358_+	serine/threonine protein kinase	A0A2I2L395	Orpheovirus	3.8e-22	32.1
WP_082842135.1\|7304280_7305351_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_157469994.1\|7305696_7305876_+	hypothetical protein	NA	NA	NA	NA
WP_157469996.1\|7306200_7307364_+\|transposase	ISKra4 family transposase	NA	NA	NA	NA
WP_082842138.1\|7307385_7308033_+	hypothetical protein	NA	NA	NA	NA
WP_052556769.1\|7308104_7308428_+	hypothetical protein	NA	NA	NA	NA
WP_082842139.1\|7308424_7309858_+	hypothetical protein	NA	NA	NA	NA
WP_157469998.1\|7309769_7310309_+	hypothetical protein	NA	NA	NA	NA
WP_157470000.1\|7310433_7311150_+	hypothetical protein	NA	NA	NA	NA
WP_082842141.1\|7311341_7311695_+	hypothetical protein	NA	NA	NA	NA
WP_082842142.1\|7311738_7311936_+	hypothetical protein	NA	NA	NA	NA
WP_082842143.1\|7312267_7313194_-	hypothetical protein	NA	NA	NA	NA
WP_082842144.1\|7313190_7313451_-	hypothetical protein	NA	NA	NA	NA
WP_162271892.1\|7313532_7313931_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_052556777.1\|7313830_7314727_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_162271979.1\|7314864_7315434_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_082842146.1\|7316197_7317535_+	hypothetical protein	NA	NA	NA	NA
WP_082842147.1\|7317541_7317802_-	hypothetical protein	NA	NA	NA	NA
WP_052556782.1\|7317819_7318563_-	pyridoxine 5'-phosphate synthase	NA	NA	NA	NA
WP_052556784.1\|7318693_7319152_-	hypothetical protein	NA	NA	NA	NA
WP_082842148.1\|7319289_7320240_-	ThuA domain-containing protein	NA	NA	NA	NA
WP_082842149.1\|7320797_7321061_+	hypothetical protein	NA	NA	NA	NA
WP_082842150.1\|7321172_7322777_+	VWA domain-containing protein	NA	NA	NA	NA
WP_157470006.1\|7322869_7324102_-	hypothetical protein	NA	NA	NA	NA
WP_162271893.1\|7324443_7324869_-	DUF3592 domain-containing protein	NA	NA	NA	NA
WP_082842153.1\|7324955_7325963_-	glycosyltransferase family 1 protein	NA	NA	NA	NA
WP_082842154.1\|7326106_7326301_+	hypothetical protein	NA	NA	NA	NA
WP_082842155.1\|7326327_7326756_+	hypothetical protein	NA	NA	NA	NA
WP_082842156.1\|7326821_7327529_-	hypothetical protein	NA	NA	NA	NA
WP_082842157.1\|7327694_7328435_-	hypothetical protein	NA	NA	NA	NA
WP_082838323.1\|7328650_7329937_+\|transposase	IS701 family transposase	NA	NA	NA	NA

DBSCAN-SWA_13

7775605 : 7833252

Staphylococcus_phage(16.67%)

transposase,integrase,tRNA

attL 7769822:7769838|attR 7813376:7813392

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
7769822:7769838	attL	NA	NA	NA	NA
WP_162271921.1\|7775605_7776718_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_052551622.1\|7777310_7778042_+	phosphoadenylyl-sulfate reductase	NA	NA	NA	NA
WP_052551620.1\|7778122_7778572_+	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_082842440.1\|7778807_7780094_+	DUF2029 domain-containing protein	NA	NA	NA	NA
WP_052551859.1\|7780056_7780512_-	ribose 5-phosphate isomerase B	NA	NA	NA	NA
WP_082842441.1\|7780508_7781543_-	hypothetical protein	A0A2H4PQT9	Staphylococcus_phage	2.3e-05	33.3
WP_082842442.1\|7782333_7783581_-	TIGR02996 domain-containing protein	NA	NA	NA	NA
WP_082842443.1\|7783753_7784821_+	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_082842444.1\|7784807_7785215_+	hypothetical protein	NA	NA	NA	NA
WP_082842445.1\|7785418_7785916_+	hypothetical protein	NA	NA	NA	NA
WP_157470085.1\|7786126_7786342_+	hypothetical protein	NA	NA	NA	NA
WP_082842447.1\|7786467_7786935_+	TIGR03067 domain-containing protein	NA	NA	NA	NA
WP_052551601.1\|7787061_7787400_+	hypothetical protein	NA	NA	NA	NA
WP_082842448.1\|7787539_7788355_+	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_082842449.1\|7788450_7789752_+	VCBS repeat-containing protein	NA	NA	NA	NA
WP_082843467.1\|7790166_7792233_+	S46 family peptidase	NA	NA	NA	NA
WP_082842450.1\|7792510_7795012_+	VWA domain-containing protein	NA	NA	NA	NA
WP_082842451.1\|7795157_7796066_+	ACP S-malonyltransferase	NA	NA	NA	NA
WP_052551591.1\|7796364_7796610_+	acyl carrier protein	B2ZXV3	Ralstonia_phage	8.2e-07	41.2
WP_082842452.1\|7796639_7797899_+	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_052561604.1\|7798100_7798640_+\|transposase	transposase family protein	NA	NA	NA	NA
WP_162271922.1\|7798636_7798774_+\|transposase	transposase	NA	NA	NA	NA
WP_082842453.1\|7798783_7799347_+	hypothetical protein	NA	NA	NA	NA
WP_162271923.1\|7799493_7800618_-\|transposase	transposase	NA	NA	NA	NA
WP_082842455.1\|7801000_7802185_+	molybdopterin-synthase adenylyltransferase MoeB	A0A1V0SAV8	Catovirus	2.1e-10	25.9
WP_052551585.1\|7802251_7803538_-	MFS transporter	NA	NA	NA	NA
WP_082842456.1\|7803738_7804662_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_082842457.1\|7804701_7805724_-	hypothetical protein	NA	NA	NA	NA
WP_082842458.1\|7805791_7807561_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_082842459.1\|7807724_7811420_-	hypothetical protein	NA	NA	NA	NA
WP_052551572.1\|7811800_7812031_+	hypothetical protein	NA	NA	NA	NA
WP_082842460.1\|7812314_7813733_-	hypothetical protein	NA	NA	NA	NA
7813376:7813392	attR	NA	NA	NA	NA
WP_082842461.1\|7813989_7817097_-	hypothetical protein	NA	NA	NA	NA
WP_157470089.1\|7817173_7818505_+	TIGR02996 domain-containing protein	NA	NA	NA	NA
WP_082842463.1\|7818529_7819000_+	TIGR02996 domain-containing protein	NA	NA	NA	NA
WP_162271924.1\|7819010_7819316_+	hypothetical protein	NA	NA	NA	NA
WP_052551562.1\|7819327_7819867_+	hypothetical protein	NA	NA	NA	NA
WP_082842465.1\|7819950_7821471_-\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	2.4e-80	38.6
WP_082842466.1\|7821518_7821878_-	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	7.3e-12	33.0
WP_082842363.1\|7821871_7822300_-	hypothetical protein	NA	NA	NA	NA
WP_082842467.1\|7822597_7824073_-	hypothetical protein	NA	NA	NA	NA
WP_082842468.1\|7824242_7824671_+	TIGR03067 domain-containing protein	NA	NA	NA	NA
WP_082842469.1\|7824730_7825156_+	TIGR03067 domain-containing protein	NA	NA	NA	NA
WP_082842470.1\|7825255_7826152_+	hypothetical protein	NA	NA	NA	NA
WP_082842471.1\|7826161_7827070_-	hypothetical protein	NA	NA	NA	NA
WP_157470091.1\|7827021_7829061_-\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	2.3e-94	44.7
WP_157470093.1\|7829372_7829780_+	hypothetical protein	NA	NA	NA	NA
WP_082842474.1\|7829949_7830177_-	hypothetical protein	NA	NA	NA	NA
WP_157470095.1\|7830926_7831433_+	hypothetical protein	NA	NA	NA	NA
WP_162271925.1\|7831434_7832295_+	hypothetical protein	NA	NA	NA	NA
WP_162271926.1\|7832466_7833252_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA

DBSCAN-SWA_14

8629149 : 8663342

Silicibacter_phage(25.0%)

protease,portal,integrase,terminase,capsid

attL 8642803:8642827|attR 8660171:8660195

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_082842919.1\|8629149_8630547_-\|capsid	phage major capsid protein	NA	NA	NA	NA
WP_157470215.1\|8630725_8631172_-	hypothetical protein	NA	NA	NA	NA
WP_157470216.1\|8631380_8631557_-	hypothetical protein	NA	NA	NA	NA
WP_157470218.1\|8631605_8631746_-	hypothetical protein	NA	NA	NA	NA
WP_162271958.1\|8631844_8632603_-	hypothetical protein	NA	NA	NA	NA
WP_082842922.1\|8632780_8633701_-	S49 family peptidase	G8DCP1	Silicibacter_phage	2.4e-30	41.9
WP_162271959.1\|8633690_8635418_-\|portal	phage portal protein	A0A142K630	Streptomyces_phage	5.8e-30	27.8
WP_082842924.1\|8635353_8635563_-	hypothetical protein	NA	NA	NA	NA
WP_082842925.1\|8635572_8637255_-\|terminase	terminase large subunit	H9YSH1	environmental_Halophage	5.1e-31	24.5
WP_162271960.1\|8637257_8637731_-\|terminase	P27 family phage terminase small subunit	NA	NA	NA	NA
WP_162271961.1\|8637877_8638093_-	HNH endonuclease	NA	NA	NA	NA
WP_157470223.1\|8638210_8638390_-	hypothetical protein	NA	NA	NA	NA
WP_082842928.1\|8638911_8639295_+	hypothetical protein	NA	NA	NA	NA
WP_082842929.1\|8639578_8640043_+	hypothetical protein	NA	NA	NA	NA
WP_082842930.1\|8640168_8640612_+	hypothetical protein	NA	NA	NA	NA
WP_157470226.1\|8640924_8641866_-	hypothetical protein	NA	NA	NA	NA
WP_082842931.1\|8642389_8642896_-	TIGR02996 domain-containing protein	NA	NA	NA	NA
8642803:8642827	attL	NA	NA	NA	NA
WP_082842932.1\|8642892_8643300_-	hypothetical protein	NA	NA	NA	NA
WP_082842933.1\|8643419_8644610_-	hypothetical protein	NA	NA	NA	NA
WP_082842934.1\|8644641_8644872_-	hypothetical protein	NA	NA	NA	NA
WP_082842935.1\|8644875_8645214_-	hypothetical protein	NA	NA	NA	NA
WP_082842936.1\|8645242_8645917_-	hypothetical protein	NA	NA	NA	NA
WP_082842937.1\|8645913_8646135_-	hypothetical protein	NA	NA	NA	NA
WP_082842938.1\|8646284_8646848_-	hypothetical protein	NA	NA	NA	NA
WP_162271962.1\|8646892_8647954_-	AAA family ATPase	Q94MN8	Myxococcus_phage	4.7e-30	38.2
WP_162271963.1\|8647994_8648762_-	hypothetical protein	NA	NA	NA	NA
WP_082842940.1\|8648896_8649154_-	hypothetical protein	NA	NA	NA	NA
WP_082842941.1\|8649187_8649550_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_082842942.1\|8649825_8650038_+	hypothetical protein	NA	NA	NA	NA
WP_082842943.1\|8650034_8650499_+	hypothetical protein	NA	NA	NA	NA
WP_157470229.1\|8650855_8651239_-	hypothetical protein	NA	NA	NA	NA
WP_162271964.1\|8651438_8652722_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_052550066.1\|8653104_8654208_+	flippase-like domain-containing protein	NA	NA	NA	NA
WP_052550064.1\|8654757_8655747_+	serine acetyltransferase	NA	NA	NA	NA
WP_052550063.1\|8655828_8656080_+	hypothetical protein	NA	NA	NA	NA
WP_052550061.1\|8656197_8656878_+	TIGR02996 domain-containing protein	NA	NA	NA	NA
WP_082842948.1\|8656880_8657651_-	3-oxoacid CoA-transferase	NA	NA	NA	NA
WP_082842949.1\|8657909_8658806_+	acyl-CoA desaturase	NA	NA	NA	NA
WP_082842950.1\|8658830_8659298_+	hypothetical protein	NA	NA	NA	NA
WP_157470523.1\|8659981_8660863_+	TIGR02996 domain-containing protein	NA	NA	NA	NA
8660171:8660195	attR	NA	NA	NA	NA
WP_082842952.1\|8661290_8663342_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: NZ_CP011271.1|WP_157469489.1|3281059_3281206_+|hypothetical-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP011271.1|WP_157469489.1|3281059_3281206_+|hypothetical-protein

3281059_3281206_+

48 aa aa

3243571-3300323

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP011271_10	Unclear	10.133\|3910131\|36\|NZ_CP011271\|CRISPRCasFinder,CRT	3910131-3910166	36	3275897-3275862	2

1. spacer 10.133|3910131|36|NZ_CP011271|CRISPRCasFinder,CRT matches to NZ_CP011271 position: 3275897-3275862, mismatch: 2

aggtcgggggaccactcggagacctgtgcgagcgcc	CRISPR spacer
aggtccggcgaccactcggagacctgtgcgagcgcc	Protospacer
***** ** ***************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP011271

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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