CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP010866	Marinovum algicola DG 898 plasmid pMaD11, complete sequence	0 crisprs	NA	0	0
NZ_CP010864	Marinovum algicola DG 898 plasmid pMaD9, complete sequence	0 crisprs	NA	0	0
NZ_CP010857	Marinovum algicola DG 898 plasmid pMaD2, complete sequence	0 crisprs	NA	0	0
NZ_CP010862	Marinovum algicola DG 898 plasmid pMaD7	0 crisprs	NA	0	0
NZ_CP010855	Marinovum algicola DG 898 chromosome, complete genome	2 crisprs	cas3,csa3,cas2,cas1,cas9,WYL,DEDDh	17	6
NZ_CP010859	Marinovum algicola DG 898 plasmid pMaD4, complete sequence	0 crisprs	NA	0	0
NZ_CP010863	Marinovum algicola DG 898 plasmid pMaD8, complete sequence	0 crisprs	NA	0	0
NZ_CP010856	Marinovum algicola DG 898 plasmid pMaD1, complete sequence	0 crisprs	NA	0	0
NZ_CP010860	Marinovum algicola DG 898 plasmid pMaD5, complete sequence	0 crisprs	WYL	0	0
NZ_CP010858	Marinovum algicola DG 898 plasmid pMaD3	0 crisprs	csa3	0	0
NZ_CP010865	Marinovum algicola DG 898 plasmid pMaD10, complete sequence	0 crisprs	NA	0	4
NZ_CP010861	Marinovum algicola DG 898 plasmid pMaD6, complete sequence	1 crisprs	csa3	1	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 2779

Enterobacteria_phage(100.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048536046.1\|1390_2779_+	AAA family ATPase	Q1MVJ3	Enterobacteria_phage	5.4e-10	26.2

DBSCAN-SWA_2

12057 : 22808

Enterobacteria_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048536059.1\|12057_14766_-	S8 family serine peptidase	A0A1V0S9L2	Catovirus	4.1e-14	26.1
WP_048536060.1\|14956_15520_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	6.5e-39	47.5
WP_048536062.1\|15516_16617_+	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	2.5e-87	48.2
WP_048536063.1\|16613_17456_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	3.7e-30	37.1
WP_048536064.1\|17455_18370_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	2.6e-85	55.3
WP_158499077.1\|18317_19124_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_053083434.1\|19484_20453_-	DUF2793 domain-containing protein	A0A0K1LM54	Rhodobacter_phage	1.4e-28	38.1
WP_048536066.1\|20652_21654_+	UDP-N-acetylglucosamine 4,6-dehydratase (inverting)	K7Y9E1	Megavirus	8.8e-39	34.4
WP_048536069.1\|21650_22808_+	UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine transaminase	A0A2K9L0G1	Tupanvirus	2.1e-28	30.9

DBSCAN-SWA_3

29333 : 30404

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048536078.1\|29333_30404_+	pseudaminic acid synthase	A0A1B1IVE2	uncultured_Mediterranean_phage	6.6e-24	33.5

DBSCAN-SWA_4

44952 : 49791

Paramecium_bursaria_Chlorella_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048536093.1\|44952_46773_-	glutamine--fructose-6-phosphate transaminase (isomerizing)	M1HMK6	Paramecium_bursaria_Chlorella_virus	9.6e-100	38.9
WP_082154730.1\|46908_47733_-	ABC transporter permease	NA	NA	NA	NA
WP_048536112.1\|47842_49120_+	sugar transporter	NA	NA	NA	NA
WP_048536095.1\|49125_49791_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.2e-06	27.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP010861

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP010861_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP010861_1

110186-110274

Orphan

Consensus_repeat	Method
GCATCATGCCCATCATCCCGCCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP010861_1

>merge|NZ_CP010861|1|110186-110274|CRISPRCasFinder
GCATCATGCCCATCATCCCGCCGCCCATCATGCCGCCACGCCGCTCCAGGCCCATCTCCCGCTCCACCATCATGCCCATCATCCCGCCG

>NZ_CP010861|1|1|110186-110274|CRISPRCasFinder
GCATCATGCCCATCATCCCGCCG	CCCATCATGCCGCCACGCCGCTCCAGGCCCATCTCCCGCTCCA
CCATCATGCCCATCATCCCGCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010861.1\|WP_048535532.1\|111801_112230_-\|Cu(I)-responsive-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133383
NZ_CP010861.1\|WP_048535536.1\|118013_119465_-\|mercury(II)-reductase	unknown	unknown	gnl\|CDD\|273944
NZ_CP010861.1\|WP_048535535.1\|114891_115203_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010861.1\|WP_048535533.1\|112318_114871_-\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|240602
NZ_CP010861.1\|WP_048535529.1\|107771_108257_-\|c-type-cytochrome	unknown	unknown	gnl\|CDD\|365823
NZ_CP010861.1\|WP_082154699.1\|120857_121298_-\|mercury-resistance-system-transport-protein-MerF	unknown	unknown	gnl\|CDD\|371528
NZ_CP010861.1\|WP_048535524.1\|106088_106370_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010861.1\|WP_048535527.1\|106681_107206_-\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
NZ_CP010861.1\|WP_048535522.1\|104650_105292_-\|SCO-family-protein	unknown	unknown	gnl\|CDD\|376869
NZ_CP010861.1\|WP_048535519.1\|103632_104193_-\|cytochrome-c-oxidase	unknown	unknown	unknown
NZ_CP010861.1\|WP_082154698.1\|115201_117517_+\|cadmium-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319783
NZ_CP010861.1\|WP_037953553.1\|122187_122589_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|133412
NZ_CP010861.1\|WP_048535538.1\|121335_121641_-\|periplasmic-mercury-ion-binding-protein	unknown	unknown	gnl\|CDD\|131107
NZ_CP010861.1\|WP_048535557.1\|104189_104633_-\|copper-chaperone-PCu(A)C	unknown	unknown	gnl\|CDD\|377298
NZ_CP010861.1\|WP_193388078.1\|108895_109771_-\|exo-alpha-sialidase	unknown	unknown	gnl\|CDD\|271234
NZ_CP010861.1\|WP_193388077.1\|121653_122091_-\|mercury-transporter	unknown	unknown	gnl\|CDD\|184301
NZ_CP010861.1\|WP_148562971.1\|108386_108884_-\|metal-binding-protein	unknown	unknown	gnl\|CDD\|225564
NZ_CP010861.1\|WP_048535537.1\|119524_120874_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224169
NZ_CP010861.1\|WP_053083415.1\|105281_106037_-\|DsbA-family-protein	unknown	unknown	gnl\|CDD\|239321
NZ_CP010861.1\|WP_048535528.1\|107202_107775_-\|DsbE-family-thiol:disulfide-interchange-protein	unknown	unknown	gnl\|CDD\|239308

Protein	Function_ID	Function_description	E-value
NZ_CP010861.1\|WP_048535532.1\|111801_112230_-\|Cu(I)-responsive-transcriptional-regulator	gnl\|CDD\|133383	cd01108, HTH_CueR, Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators. Helix-turn-helix (HTH) transcription regulators CueR and ActP, copper efflux regulators. In Bacillus subtilis, copper induced CueR regulates the copZA operon, preventing copper toxicity. In Rhizobium leguminosarum, ActP controls copper homeostasis; it detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations. These proteins are comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain winged HTH motifs that mediate DNA binding, while the C-terminal domains have two conserved cysteines that define a monovalent copper ion binding site. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	1.18947e-68
NZ_CP010861.1\|WP_048535536.1\|118013_119465_-\|mercury(II)-reductase	gnl\|CDD\|273944	TIGR02053, Mercuric_reductase, mercury(II) reductase. This model represents the mercuric reductase found in the mer operon for the detoxification of mercury compounds. MerA is a FAD-containing flavoprotein which reduces Hg(II) to Hg(0) utilizing NADPH. [Cellular processes, Detoxification].	6.89331e-153
NZ_CP010861.1\|WP_048535528.1\|107202_107775_-\|DsbE-family-thiol:disulfide-interchange-protein	gnl\|CDD\|239308	cd03010, TlpA_like_DsbE, TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c maturation (Ccm) factor with a redox active CXXC motif. Assembly of cytochrome c requires the ligation of heme to reduced thiols of the apocytochrome. In bacteria, this assembly occurs in the periplasm. The reductase activity of DsbE in the oxidizing environment of the periplasm is crucial in the maturation of cytochrome c.	5.75191e-68
NZ_CP010861.1\|WP_048535533.1\|112318_114871_-\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|240602	cd12919, VKOR_2, Vitamin K epoxide reductase family in bacteria. This family includes vitamin K epoxide reductase (VKOR) present only in bacteria. VKOR (also named VKORC1) is an integral membrane protein that catalyzes the reduction of vitamin K 2,3-epoxide and vitamin K to vitamin K hydroquinone, an essential co-factor subsequently used in the gamma-carboxylation of glutamic acid residues in blood coagulation enzymes. All homologs of VKOR contain an active site CXXC motif, which is switched between reduced and disulfide-bonded states during the reaction cycle. In some bacterial homologs, the VKOR domain is fused with domains of the thioredoxin family of oxidoreductases which may function as redox partners in initiating the reduction cascade.	1.47895e-85
NZ_CP010861.1\|WP_082154699.1\|120857_121298_-\|mercury-resistance-system-transport-protein-MerF	gnl\|CDD\|371528	pfam11431, Transport_MerF, Membrane transport protein MerF. The mercury transport membrane protein, MerF has a core helix-loop-helix domain. It has two vicinal pairs of cysteine residues which are involved in the transport of Hg(II) across the membrane and are exposed to the cytoplasm.	5.49752e-08
NZ_CP010861.1\|WP_048535529.1\|107771_108257_-\|c-type-cytochrome	gnl\|CDD\|365823	pfam00034, Cytochrom_C, Cytochrome c. The Pfam entry does not include all Prosite members. The cytochrome 556 and cytochrome c' families are not included. All these are now in a new clan together. The C-terminus of DUF989, pfam06181, has now been merged into this family.	1.21903e-15
NZ_CP010861.1\|WP_048535527.1\|106681_107206_-\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	2.96764e-38
NZ_CP010861.1\|WP_048535522.1\|104650_105292_-\|SCO-family-protein	gnl\|CDD\|376869	pfam02630, SCO1-SenC, SCO1/SenC. This family is involved in biogenesis of respiratory and photosynthetic systems. SCO1 is required for a post-translational step in the accumulation of subunits COXI and COXII of cytochrome c oxidase. SenC is required for optimal cytochrome c oxidase activity and maximal induction of genes encoding the light-harvesting and reaction centre complexes of R. capsulatus.	7.89744e-69
NZ_CP010861.1\|WP_037953553.1\|122187_122589_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|133412	cd04785, HTH_CadR-PbrR-like, Helix-Turn-Helix DNA binding domain of the CadR- and PbrR-like transcription regulators. Helix-turn-helix (HTH) CadR- and PbrR-like transcription regulators. CadR and PbrR regulate expression of the cadmium and lead resistance operons, respectively. These proteins are comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the C-terminal domains have three conserved cysteines which comprise a putative metal binding site. Some members in this group have a histidine-rich C-terminal extension. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	6.38257e-66
NZ_CP010861.1\|WP_048535538.1\|121335_121641_-\|periplasmic-mercury-ion-binding-protein	gnl\|CDD\|131107	TIGR02052, periplasmic_mercuric_ion_binding_protein, mercuric transport protein periplasmic component. This model represents the periplasmic mercury (II) binding protein of the bacterial mercury detoxification system which passes mercuric ion to the MerT transporter for subsequent reduction to Hg(0) by the mercuric reductase MerA. MerP contains a distinctive GMTCXXC motif associated with metal binding. MerP is related to a larger family of metal binding proteins (pfam00403). [Cellular processes, Detoxification].	5.63042e-08
NZ_CP010861.1\|WP_048535557.1\|104189_104633_-\|copper-chaperone-PCu(A)C	gnl\|CDD\|377298	pfam04314, PCuAC, Copper chaperone PCu(A)C. PCu(A)C is a periplasmic copper chaperone. Its role may be to capture and transfer copper to two other copper chaperones, PrrC and Cox11, which in turn deliver Cu(I) to cytochrome c oxidase.	3.24452e-35
NZ_CP010861.1\|WP_082154698.1\|115201_117517_+\|cadmium-translocating-P-type-ATPase	gnl\|CDD\|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_CP010861.1\|WP_193388077.1\|121653_122091_-\|mercury-transporter	gnl\|CDD\|184301	PRK13751, PRK13751, putative mercuric transport protein; Provisional.	6.28082e-16
NZ_CP010861.1\|WP_148562971.1\|108386_108884_-\|metal-binding-protein	gnl\|CDD\|225564	COG3019, COG3019, Predicted metal-binding protein [General function prediction only].	1.45708e-35
NZ_CP010861.1\|WP_048535537.1\|119524_120874_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224169	COG1249, Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion].	5.55603e-135
NZ_CP010861.1\|WP_053083415.1\|105281_106037_-\|DsbA-family-protein	gnl\|CDD\|239321	cd03023, DsbA_Com1_like, DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC motif, assumed to be imbedded in a DsbA-like structure. Its homology to DsbA suggests that the protein is a protein disulfide oxidoreductase. The role of such a protein in pathogenesis is unknown.	6.11618e-70
NZ_CP010861.1\|WP_193388078.1\|108895_109771_-\|exo-alpha-sialidase	gnl\|CDD\|271234	cd15482, Sialidase_non-viral, Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.	6.32104e-06

>NZ_CP010861.1|WP_193388078.1|108895_109771_-|exo-alpha-sialidase
MGAAAVLVLSGAVRAGDGAADIRTLAFDGDTLLAADATLMISPDGGRNWEERPTPAPVASLATHPARPGRILAGLARGRVAMSGDGGATWTTRSDGLASGEVTALAVAAGNPDMIYAAIRGDGLWKSEDAGATWALAMDRPWLDAAELDPLTLASVDLETGMGGIWIYAGTEKGLTRVPDCFCRWQDFQPGDAMDALAAGDAPPAEASLPTDEPVLSLASALTAPSTLYAALPSGVWASQDGGVIWTHKAKGQGRAVAVHPRDENHVAAILDGTLKLSRDGGATWIALAVA
>NZ_CP010861.1|WP_148562971.1|108386_108884_-|metal-binding-protein
MNRRIFLASLVAIGVGGTFTFTTLTSAQSTEHATGPTSSDTAGGSKQITIWRDPGCGCCDTYADYLEENGYQVTRIDDRDFDKRSVEVGVPEQGLGCHLAEIDRYFVSGLVPVDIMERLVAEQPDITGITLPGMPANAPGMARVKTGTLKTYAFGEGGITVYSDE
>NZ_CP010861.1|WP_048535529.1|107771_108257_-|c-type-cytochrome
MRRTATIGAAIVALSAIGFAVLAQSESDEDLVEGLTFLGEPVTAADIEAGQTLYAENCASCHGANLEGQPDWRRRLDNGRMPAPPHDETGHTWHHSDRNLFVVTKGGVGAVVPSYESDMPAFEGILTDDEIADVLSYIKSTWPDRQRQFQAEVTANDRGAP
>NZ_CP010861.1|WP_048535528.1|107202_107775_-|DsbE-family-thiol:disulfide-interchange-protein
MSATEEPRRRKGRILALVPVAIFALVGGAFYWGLFNNDDRLPSTLIGKAVPEFDLPPIEGRADGLSTADLKGQVSIVNVWASWCVPCRVEMPLLNELAARDEVAIFGINYKDRPEEALGFLSELGDPYTRIGADRNGRVSIDWGVYGLPETFVIDAEGRIAYKHIGPFNRRSLEEDILPVVRRLQEGAGS
>NZ_CP010861.1|WP_048535527.1|106681_107206_-|TlpA-family-protein-disulfide-reductase
MKRRELLAGMAAIGVAGPVQARPLMPLHEKPREMLSPPFVDGAGRDLTLADFRGRVVLLNIWATWCVPCREEMPTLDALQEKLGGDDFHVLPLSIDRAGMRVVRSFYEEIGIRHLDMYLADSTRAMLAFGALGLPTTILIDRDGFERGRLVGPAEWDSPEVMAQIQTIINERSE
>NZ_CP010861.1|WP_048535524.1|106088_106370_-|hypothetical-protein
MTLIKKLSMATAVSTLLATGVFAQDNTGSSGQMMDGENGMAGNMMDGDMSGMDGMMPMMKMMQKMGPMMEACTEMMEAMNNSENETAPSTDKG
>NZ_CP010861.1|WP_053083415.1|105281_106037_-|DsbA-family-protein
MILKTALRVFAVFLWALISTPTISLAQQSTPLDQVEQEAIKALILQTIRENPEVLMDTLLTFQEEAQAQAQAEQRAAIQRVGDLLLADANTGVMGNPEGDIVLVEFFDYNCPYCRRAAPVLFELIEENPDLRIIMREWPILGPDSELAARASLAAIKQNKFEAFHEALMAQPRANTVFIRRAAEQAGLDYDQLQADMDAPEVDAHIAKSHDLARQLGISGTPTFLIGEALVPGLLEKADLQALIAEAGDVD
>NZ_CP010861.1|WP_048535522.1|104650_105292_-|SCO-family-protein
MSIEPGDTPSKARLLRTILWGTITAALAGLAIFWALDNYLGNGSKAVRYSGEADIRSEFSLIDHTGQEVTQADYADRWQLVFFGFTNCPDVCPTTLAYMASVLDLLGKDADQVAPIFITVDPERDTVPVMAEYVSAFHPRLIGLTGTGAQVAEATRSFRTWYERTEDDSAPDGYFMAHGGYIYLMQPSGEFEAVYQEGGQPPEALAQEIRKKL
>NZ_CP010861.1|WP_048535557.1|104189_104633_-|copper-chaperone-PCu(A)C
MKITALATVLTLWPFFASADVTISDGWARASILASRPAAAYLTLTSNQSDQLVAITTPIAGNVTIHAVETDNDGISRMVEVDGLDLPSGEPVTLAPGSMHLMLMGLSEKLEEGTDLPLILTFASGARMEISVPVLGPGAMRPQEQQP
>NZ_CP010861.1|WP_048535519.1|103632_104193_-|cytochrome-c-oxidase
MKDILLLIALVAGLPAYADHPGDRLDEVMAQKEPAFTAVDLNELPALGLLGPDGEPLDLESLSDQVVVLSFVSSDCGQPCADQQALLGKVRGGVNASPMLDMVTFLVVTDASDPVPGPIAKNVVIARAQEPIENLIDQYRAIAPDHPEAPLVHVIARGNRHAGVYAGSGFRHINMILYVNGLTNAH
>NZ_CP010861.1|WP_048535532.1|111801_112230_-|Cu(I)-responsive-transcriptional-regulator
MNIGNVSEQSGLPAKTIRYYEDIGLVQPSRRENGYRDFAVQDLHKLAFLGRARSLGFGIEECRTLLSLYEDRERSSADVKAIAQSHLARVDQKIEELQALSATLRDLVARCHGDDRPDCPIMDDLTPSDLAGTRKHRAGTTL
>NZ_CP010861.1|WP_048535533.1|112318_114871_-|NAD-dependent-epimerase/dehydratase-family-protein
MADESKPVVIVTGSSGYLGAAVVRRLHGSYRVVGLDRYSPPHPPHQAECVCFDITDQASVDTALDRVRLAYGDSIAACIHLAAYFDLTGEDDPAYDAVTVEGSKRLLNGLQEFKLEQFVFASTMLAHAATEPGQPISEDHPFDPKLPYRASKVRTESMLREERGDEKLVLMRPAGIYDDKGQSTFLTRQIARIHEKRFSGRVYPGDLSRGQAFLHLEDFLDAVERIVDRRAKLPDVFPVLLGESDPIPFGDLQRLIGRELHGEDWITWNVPPRLAKLGTWTENKILGEDAFIRSWMVDISSDHYELDLSAAKKHLDWTPQHSLREDMPGILQRLKDDPYEWYEVNGLNAARVSASKVENAAAEEAAEKAPTEAEANENRREHEDHMRQMHFSMLWVHWLVMALGLWLATAPSVFGTFDQTEFSAAVQRVTEDRGLWAAATRSWLTAWNDVFTGLAIMVFAALSLRPGNGWAQWANAALGVWLLAAPLVFWTPDAAVYANDTLIGALVIALTILIPMMPGMSREGMMDDTDIPPGWTYCPSTYVQRLPIIALGVVGFILSRVLSAYQLGHVDGVWEPFFSSPSALNGTEYIVTSDVSKAWPIADGGLGAMSYMFEIMMGVMGSRLRWRTMPWMVALFGIVVGPLGVVSIYFIIIQPITIGTYCTICLMAALAMLIMIPFSLDEIVAMVQFMVWNTRRGRPFWRAFFRGDALPGGTTGGEMSFDARPMQIFRQSARGVTVPWTLGLSAAIGAFLMLSRAIFGNEATMANSDHLLGALVLTTAVIAWAEVARPLRFLNILFGLWLIIAPWLLDGGTVAGSLVGILAGIALIALSLPRGKRSEEHYGSWDRFIV
>NZ_CP010861.1|WP_048535535.1|114891_115203_-|hypothetical-protein
MSGSFGRLLTFHVMLLVTGRSIEDPQLFSQFHCGRKIPTFQRWKLKPNANDLVEPVATERRKKIMMDGGMMGGGMMLGMGIVWLLVIVVLVLAIIALVKYLRT
>NZ_CP010861.1|WP_082154698.1|115201_117517_+|cadmium-translocating-P-type-ATPase
MDTSKTETREATDPVCGMKVDHATAKHRSTHAGKEFMFCSSRCKNKFDAEPETYLGAGPAPEPMPEGTIFTCPMHPEIEQVGPGDCPICGMALEPKGVPTGEEGPNPELVDFTRRFWIGAALTIPVVLLAMGGYVGMPIRDWTGERLAHWLELILATPVILWVGWPFLVRGWKSFRTLNLNMFSLIAMGVFAAWTFSTVAVIAPGLFPAGFRDDQGNVGIYFEAGAVIVVLVLLGQILELRARERTGSAIRALLDLAAKSARIIRADGSEEEVALEDVQIGDHVRVRPGEKVPVDGEVIDGRSSVDESMLTGEPVPVEKVTGDAVTGATINGTGSIIIEAKRVGEDTMLAQIVEMVAAAQRSRAPIQKLADAVAGYFVPAVIAVAIASFIAWSIWGPTPALAYGLVSAIAVLIIACPCALGLATPMSIMTATGRGAQAGVLIKNAEALEAFEKVDTLIVDKTGTLTLGKPELAAVLPEDGHDEAEVLRLAASLERGSEHPLAEAIVRGAEARGIDLANAKDFEAVTGMGVRGSVDGKSVALGNARMLGELGIDAPAATEVANARRDEGETVMFVIIDGSVAGLVSVADPVKESTPAALKALHELGFRIVMATGDNERTARAVASRLGIDDVRADVLPKDKARIIRELQAEGRKVAMAGDGVNDAPALAQADVGIAMGTGADVAIESAGFTLLKGDLNGLVRARRLSLATMRNIRQNLFFAMIYNTAGVPIAAGILYPFFGLLISPMFAAAAMSLSSVSVIGNALRLRTVRL
>NZ_CP010861.1|WP_048535536.1|118013_119465_-|mercury(II)-reductase
MDQTVKKKDCCSSKELSGDQYDLIVVGAGSAGFSASITAAEAGKRVALVGHGTIGGTCVNVGCVPSKAMIRAAEAAHGGASAARFPGIVPCAHAVDWTAVVKGTADLVKEMRHKKYIDLLPAYENVSYIEEGPARLVEGGVAVGGRVISAPRVLIATGSRPHIPLIDEIEAVETLDSWGLLTLPDRPESILVLGGGYIGCELAQMVSRLGVKVTLVTRSRLLPGVEPEVTEALTEALKVEGITVETGLAYVSVAKAAGGVSLTVERGGKTEDLTAERLVVTTGRIANSENLGLEELGIETDACGSIKVGQDMATTRAGVWAAGDVTDRDQFVYMAAYAAKVAINNALGLEPMRYDNAAMPWVVFTDPQVAGVGLSEAEAKKAGYDVKTSVITLDNVPRAAAARDTRGLIKLVADAKTDRLLGGQIAAPEGSDTIQTLAMALKFGMTARALGETIFPYLTTVEGLKLAAQTFDKDVAKLSCCAG
>NZ_CP010861.1|WP_048535537.1|119524_120874_-|NAD(P)/FAD-dependent-oxidoreductase
MTKTYDLIVIGGGTAGNGVARMAADASWSVASIDSEPHGGTCALRGCDPKKMLVAVTEGVEFAENMEGKGLEAQPSVNWPDMIAFKRSFTDDMPPRIESGMEKAGIDVLHGEVRFTGSDTIELNGETLTAKHFHIATGARPMTLNIPGEEHLTTSTEFLELPDRPDRIAFVGGGFIAMEFAHIVKRAGSSEVTVLEMADRPLGNFDPDLVEMLVEGTEELGIDLRTKAKVTKIEKQGDEFTVTVERADGTEIVTCDLVVHGTGRVPNIDGLNLEAAGVEYSRRGINVSDAMRTTNPAIFAAGDCADSGPKLTPVSAFEGRVAGKNLLAGEDERTVDYPPIPSVVFTLPMVATVGLSEAVAREQGLKFDTHFEKTGDWYSSLRVGAKHTGFKVLVEEGSGQILGAHLIGPGSEEQINLFAMAMGAGQTANQIKAMIFAYPSYASDIGSMV
>NZ_CP010861.1|WP_082154699.1|120857_121298_-|mercury-resistance-system-transport-protein-MerF
MTDMNNNNEPTTLLRRGLIGSVFAAICCFTPFLVLIVAGVGLSAVVGWLDYALFPMLFASLSAVAYALWQQAGRPGHSPKALLIGLAVVLSALLFWLEFRFALRISVAAALAVAGYALWLRKSGSSAVSRIKRNWHKERNRYDQDV
>NZ_CP010861.1|WP_048535538.1|121335_121641_-|periplasmic-mercury-ion-binding-protein
MKSLHLALAVVGTLAASPASAAEQRINIGVGELTCPTCSYTVAAAMRGVPSVEIIDFMEGEEFGTGTYIVAFDDEAADQDMIVEAIRATGYSADIVESGDF
>NZ_CP010861.1|WP_193388077.1|121653_122091_-|mercury-transporter
MTETTSADRQTAMDETGAADKKAWTTTWLGALGALAMTSCCILPLVLVSFGVTGVFIAQLGVLYQYKWITFALSAACIGYGFYKAYRPIPTEACADGTCARPMCADGTCARPMNRTLMRSILWIATAIVTVAMIFPYLTPYLLSY
>NZ_CP010861.1|WP_037953553.1|122187_122589_+|helix-turn-helix-domain-containing-protein
MKVLRRGDLARLTGCNLETIRYYENIGVMPEPPRSSKNYRVYDDRHVARLCFIMRARELGFTLDEVRDLLALVDGGAQTCGEVQGLANSHLASVRAKIDDLKRIERVLSSTVAQCTGDDVPECPVIDALTEVT

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP010861_1	1.1\|110209\|43\|NZ_CP010861\|CRISPRCasFinder	110209-110251	43	NZ_CP010861	Marinovum algicola DG 898 plasmid pMaD6, complete sequence	110209-110251	0	1.0
NZ_CP010861_1	1.1\|110209\|43\|NZ_CP010861\|CRISPRCasFinder	110209-110251	43	NZ_CP031599	Roseovarius indicus strain DSM 26383 plasmid pRIdsm_01, complete sequence	428205-428247	2	0.953

1. spacer 1.1|110209|43|NZ_CP010861|CRISPRCasFinder matches to NZ_CP010861 (Marinovum algicola DG 898 plasmid pMaD6, complete sequence) position: , mismatch: 0, identity: 1.0

cccatcatgccgccacgccgctccaggcccatctcccgctcca	CRISPR spacer
cccatcatgccgccacgccgctccaggcccatctcccgctcca	Protospacer
*******************************************

2. spacer 1.1|110209|43|NZ_CP010861|CRISPRCasFinder matches to NZ_CP031599 (Roseovarius indicus strain DSM 26383 plasmid pRIdsm_01, complete sequence) position: , mismatch: 2, identity: 0.953

cccatcatgccgccacgccgctccaggcccatctcccgctcca	CRISPR spacer
cccatcatgcctccacgcggctccaggcccatctcccgctcca	Protospacer
*********** ****** ************************

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP010855

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP010855_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP010855_1

1542798-1542896

Orphan

Consensus_repeat	Method
GGCGTATTTTGAAAGAGAAGAATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP010855_1

>merge|NZ_CP010855|1|1542798-1542896|CRISPRCasFinder
GGCGTATTTTGAAAGAGAAGAATGCGGCGGTGGGGTGAGTTTCCGGGGGCGTTGCGCTGAGGCAGATGTCGTGCGGCGTATTTTGAAAGAGAAGAAGCC

>NZ_CP010855|1|1|1542798-1542896|CRISPRCasFinder
GGCGTATTTTGAAAGAGAAGAATGC	GGCGGTGGGGTGAGTTTCCGGGGGCGTTGCGCTGAGGCAGATGTCGTGC
GGCGTATTTTGAAAGAGAAGAAGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010855.1\|WP_048531329.1\|1533031_1533391_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010855.1\|WP_048531349.1\|1545970_1547578_+\|bifunctional-ADP-dependent-NAD(P)H-hydrate-dehydratase/NAD(P)H-hydrate-epimerase	unknown	unknown	gnl\|CDD\|238576
NZ_CP010855.1\|WP_048531355.1\|1550984_1551785_-\|TatD-family-hydrolase	unknown	unknown	gnl\|CDD\|223162
NZ_CP010855.1\|WP_048531345.1\|1543940_1545347_-\|type-I-glutamate--ammonia-ligase	unknown	unknown	gnl\|CDD\|181884
NZ_CP010855.1\|WP_048531357.1\|1551793_1552924_-\|DNA-polymerase-III-subunit-delta'	unknown	unknown	gnl\|CDD\|236022
NZ_CP010855.1\|WP_048531353.1\|1549194_1550124_-\|AEC-family-transporter	unknown	unknown	gnl\|CDD\|223751
NZ_CP010855.1\|WP_048531342.1\|1541494_1542703_+\|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein	unknown	unknown	gnl\|CDD\|238430
NZ_CP010855.1\|WP_048531338.1\|1540072_1541164_+\|UDP-3-O-(3-hydroxymyristoyl)glucosamine-N-acyltransferase	unknown	unknown	gnl\|CDD\|234858
NZ_CP010855.1\|WP_158499052.1\|1535466_1535967_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369942
NZ_CP010855.1\|WP_048531351.1\|1548372_1549263_+\|DUF2520-domain-containing-protein	unknown	unknown	gnl\|CDD\|378484
NZ_CP010855.1\|WP_048533752.1\|1550187_1550988_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293837
NZ_CP010855.1\|WP_048531347.1\|1545464_1545803_-\|P-II-family-nitrogen-regulator	unknown	unknown	gnl\|CDD\|223424
NZ_CP010855.1\|WP_048533748.1\|1534711_1535083_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010855.1\|WP_082154444.1\|1547574_1548096_-\|Hint-domain-containing-protein	unknown	unknown	gnl\|CDD\|372590
NZ_CP010855.1\|WP_048531340.1\|1541199_1541460_+\|phosphopantetheine-binding-protein	unknown	unknown	gnl\|CDD\|179197
NZ_CP010855.1\|WP_082154443.1\|1538424_1540041_+\|L,D-transpeptidase-family-protein	unknown	unknown	gnl\|CDD\|225536
NZ_CP010855.1\|WP_048533749.1\|1535979_1537173_-\|lytic-murein-transglycosylase	unknown	unknown	gnl\|CDD\|372592
NZ_CP010855.1\|WP_048531336.1\|1537511_1538081_-\|DUF882-domain-containing-protein	unknown	unknown	gnl\|CDD\|283577
NZ_CP010855.1\|WP_048531343.1\|1542953_1543769_-\|lytic-murein-transglycosylase	unknown	unknown	gnl\|CDD\|372592
NZ_CP010855.1\|WP_048531331.1\|1533407_1534715_-\|relaxase/mobilization-nuclease-domain-containing-protein	unknown	unknown	gnl\|CDD\|237171

Protein	Function_ID	Function_description	E-value
NZ_CP010855.1\|WP_048531349.1\|1545970_1547578_+\|bifunctional-ADP-dependent-NAD(P)H-hydrate-dehydratase/NAD(P)H-hydrate-epimerase	gnl\|CDD\|238576	cd01171, YXKO-related, B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily.	1.25738e-67
NZ_CP010855.1\|WP_048531355.1\|1550984_1551785_-\|TatD-family-hydrolase	gnl\|CDD\|223162	COG0084, TatD, Mg-dependent DNase [DNA replication, recombination, and repair].	1.44531e-102
NZ_CP010855.1\|WP_048531345.1\|1543940_1545347_-\|type-I-glutamate--ammonia-ligase	gnl\|CDD\|181884	PRK09469, glnA, glutamate--ammonia ligase.	0
NZ_CP010855.1\|WP_048531357.1\|1551793_1552924_-\|DNA-polymerase-III-subunit-delta'	gnl\|CDD\|236022	PRK07471, PRK07471, DNA polymerase III subunit delta'; Validated.	1.12205e-146
NZ_CP010855.1\|WP_048531353.1\|1549194_1550124_-\|AEC-family-transporter	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	1.20775e-39
NZ_CP010855.1\|WP_048531342.1\|1541494_1542703_+\|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein	gnl\|CDD\|238430	cd00834, KAS_I_II, Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.	6.4545e-180
NZ_CP010855.1\|WP_048531338.1\|1540072_1541164_+\|UDP-3-O-(3-hydroxymyristoyl)glucosamine-N-acyltransferase	gnl\|CDD\|234858	PRK00892, lpxD, UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional.	1.27986e-115
NZ_CP010855.1\|WP_158499052.1\|1535466_1535967_+\|hypothetical-protein	gnl\|CDD\|369942	pfam08548, Peptidase_M10_C, Peptidase M10 serralysin C terminal. Serralysins are peptidases related to mammalian matrix metallopeptidases (MMPs). The peptidase unit is found at the N terminal while this domain at the C terminal forms a corkscrew and is thought to be important for secretion of the protein through the bacterial cell wall. This domain contains the calcium ion binding domain pfam00353.	1.45977e-05
NZ_CP010855.1\|WP_048531351.1\|1548372_1549263_+\|DUF2520-domain-containing-protein	gnl\|CDD\|378484	pfam10728, DUF2520, Domain of unknown function (DUF2520). This presumed domain is found C-terminal to a Rossmann-like domain suggesting that these proteins are oxidoreductases.	2.98867e-33
NZ_CP010855.1\|WP_048533752.1\|1550187_1550988_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293837	cd16279, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry. Some members of this subgroup are named as octanoyltransferase (also known as lipoate-protein ligase B).	4.70509e-86
NZ_CP010855.1\|WP_048531347.1\|1545464_1545803_-\|P-II-family-nitrogen-regulator	gnl\|CDD\|223424	COG0347, GlnK, Nitrogen regulatory protein PII [Amino acid transport and metabolism].	4.63967e-57
NZ_CP010855.1\|WP_082154444.1\|1547574_1548096_-\|Hint-domain-containing-protein	gnl\|CDD\|372590	pfam13403, Hint_2, Hint domain. This domain is found in inteins.	1.09683e-27
NZ_CP010855.1\|WP_048531340.1\|1541199_1541460_+\|phosphopantetheine-binding-protein	gnl\|CDD\|179197	PRK00982, acpP, acyl carrier protein; Provisional.	2.54959e-10
NZ_CP010855.1\|WP_082154443.1\|1538424_1540041_+\|L,D-transpeptidase-family-protein	gnl\|CDD\|225536	COG2989, COG2989, Uncharacterized protein conserved in bacteria [Function unknown].	6.23974e-109
NZ_CP010855.1\|WP_048533749.1\|1535979_1537173_-\|lytic-murein-transglycosylase	gnl\|CDD\|372592	pfam13406, SLT_2, Transglycosylase SLT domain. This family is related to the SLT domain pfam01464.	2.81806e-121
NZ_CP010855.1\|WP_048531336.1\|1537511_1538081_-\|DUF882-domain-containing-protein	gnl\|CDD\|283577	pfam05951, Peptidase_M15_2, Bacterial protein of unknown function (DUF882). This family consists of a series of hypothetical bacterial proteins of unknown function.	1.76044e-43
NZ_CP010855.1\|WP_048531343.1\|1542953_1543769_-\|lytic-murein-transglycosylase	gnl\|CDD\|372592	pfam13406, SLT_2, Transglycosylase SLT domain. This family is related to the SLT domain pfam01464.	6.15572e-54
NZ_CP010855.1\|WP_048531331.1\|1533407_1534715_-\|relaxase/mobilization-nuclease-domain-containing-protein	gnl\|CDD\|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	0.00609739

>NZ_CP010855.1|WP_048531342.1|1541494_1542703_+|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein
MKRVVITGAGTVNALGQNVPDTMAAMREGRCGIGTLDIADLDRLAIKIGGQVRDFDPEAWFNRQQLSLYDRFTQFTLVAGREAMAQSGLEFTDELAARAGVILGNSGGGMNTLDENYRSVYEDGKNRVHPFVVPKLMNNAAASHVSMEFNLKGPSFTVSTACASSNHAMSLAFQMVQGGMTPAMVTGGSEAMLCFGGVKAWEGLRVMSKDGCRPFSANRNGMVQGEGAAVFVFEELEHARKRGAEILAEVVGFAMSSDASDIVMPSKSGAARAIRGALVDARVDATEVGYINAHGTGTAANDKTESAAVADVFGAHADKLMISSTKSMHGHLIGGTGAVELLACIMAVRDGVIAPTIGYEEPDPECALDVVPNEAREADVDVALSNAFAFGGLNAVLALRRF
>NZ_CP010855.1|WP_048531340.1|1541199_1541460_+|phosphopantetheine-binding-protein
MDVKDKVVEIIAEQAVLEKSDVSMDNTLEDLGIDSLGLVESIFAIEEAFDISIPFNANEPTESDFDISSVGSIVAGIKKLIAEQKG
>NZ_CP010855.1|WP_048531338.1|1540072_1541164_+|UDP-3-O-(3-hydroxymyristoyl)glucosamine-N-acyltransferase
MTYTVQDIAAALGCEAAGATDISIEAVREPAEAGPEHLALAMKPEFAETLSQGRARAALLWTGADWQALGLEAAIFAQRPRFALSGLSQMMDPGARYPQGIHPTAVIDPSAEIGEGVTIGPLAMVGPNAVIGARSVIGPQCYIGAEVRLGEDALLHAQVTVAHGVTIGARFMAQSGARIGSDGFSFVTPEKSGAERARETLGDQGEAKAQSWARIHSLGGVTIGNDVEVGSNTCIDRGTVRDTVIGDGTKIDNLVQIGHNCIIGKDCLICGHVGFAGSVKTGNNCVFGGQTGIADNLFIGDNVISGGGTTILSNVPSGRVMLGYPATKMDVQTESYKAIRRLPRLMRDVAALKKAVSKQGESD
>NZ_CP010855.1|WP_082154443.1|1538424_1540041_+|L,D-transpeptidase-family-protein
MTQSQKASGFRSLMGGVALAIATLGLPSQPAFAQVTAFKQAVAESASADRDIAAFYRENGFAPIWTGDSDIHRARRAALLQAVSRASLYGLPADKYHPDVLRGKLASVQGERALGALEVELSETLVLFSRHMQTGVLNPQKVTNGIKREAPLRDPITYLRDFTSGDPDAFFRTILPTSAEYTRLIRAKFELEQVVASGGWGALVQTDKVSPGDIGAAVVALRNRLIAMGYLDRSNSATYDNALQKAVQDYQVDQGLEPDGVAGAATLRAINVPASERLKSVLVAMERERWFNRPRGARHVLVNIPDFKARIIDNDKVTFETRSVVGKDTPDRETPEFSDVMEYMEINPYWNVPRSIASEEYLPAMRRNPYAAGHLQVIDGRGRVVPRSSINFARYSGRTFPFNLRQPPSDKNALGLVKFMFPNKYNIYLHDTPAKSLFSNEVRAFSHGCVRLNDPFDFAYELLSRQTDDPVDFFQTRLQSGQNIRVPLDEPVPVHLIYRTAYTDAKGRLKFRADIYGRDAMVYRALQNAGVALTSVQG
>NZ_CP010855.1|WP_048531336.1|1537511_1538081_-|DUF882-domain-containing-protein
MTELRGSGISRRGLLGAFAATLVTAAPTYSNAAGFLRGGGDIRRIKMYSARTGERLDMIYWVEGDYIKDAVEEVHKFMRDWRTNDVKYIDLRAIDILAASHNLLDVPEPYMLLSGYRSPKTNAMLRARSSGVAKNSLHLKGQAADVSLKGRSVNQIAKAATACRAGGVGRYSSSNFVHMDCGAVRSWGR
>NZ_CP010855.1|WP_048533749.1|1535979_1537173_-|lytic-murein-transglycosylase
MTAQAQDKPAIERQFQSWIQSEIWPRARAKGVSRATFDAAFSGVTLNWDLPDLVPPGTAPETPKRQRQAEFGAPSKYFNRNSIDGATRIGKQMAQRHATALAQSERRTGVPGRIILAIWGRESGYGRVAIPHNVFRVLGTKGFMSTRAEYFSAELIAALQIAEAGHAPESAMKSSWAGALGQPQFMPSSFLNYAADGNGDRKADIWRSEADTIASIGNYLAEHGWVAGRDWGFEVMVPDAVSCTLEGPDQGRPIADWAAMGITRVSGRPFPAHELPGEGYLMMPAGRHGPAFVVTPNFYVLKDYNTSDLYALFVGHVGDRIRFNVGDFRQAWGRVDRLFRSDIAAAQRSLEAMGHDVGGADGLPGYKTRRSIGRWQEARGRQATCFPDTGNIAALGG
>NZ_CP010855.1|WP_158499052.1|1535466_1535967_+|hypothetical-protein
MRIVPPGGHEYRLRAGKQYRCRDHGHGNRNRRCGAERPDIHRQRNRREPGEYLCRGGDGNDRIHGNQGRDVIAGGSGDDDLRGGTRADEFLVAPGRGNDTISDFGHFQDAIVVSVALLGPATTGAEVIAMFADTSSGVAVPDFGSETITFSNLTHFDDMADNIFIA
>NZ_CP010855.1|WP_048533748.1|1534711_1535083_-|hypothetical-protein
MRLSFEERARLEHDAAGMSLGAYIRDRLFGEDVAPRQSRGKFPVKDYAALGRVLAALGASRLSSNLNQLAKAVNTGSLPVTPETEEDVRQACKDVQAMRRDLLIALGLHESGSASKAGMDLKP
>NZ_CP010855.1|WP_048531331.1|1533407_1534715_-|relaxase/mobilization-nuclease-domain-containing-protein
MILKAKERGGGAQLARYLLSMRDNDHVELHDVRGFVGDELLDAFREIDAIAKGTRCENYLFSASLNPPGGATVTSEDFEKAADEVERSLGLEGQPRAIVFHEQDGRRHAHVVWSRIDAEHMRAINLSHYKMRLKEVSRDLFRAHGWDMPKGLRDWRERDPLSYTREEWQQARRVGLNPKQLKAMFQECWNRSDNGTAFAQALKERGFMLAQGDRGGVVAVDYRGEVYAVARQVGVRTKDVVARLGDPASLPSVDEARVEIASRMSERIQGFIRQAEREAQSGKKALEFERSELFGRQRQERKELLTAQEKRWIAETNARAERLPRGISGLWHRLTGKYGKIRQQNEREAWSALLRDRAERDDMIAGQLEERRALQIRIREQREREQGDLLLLREDVARYQDLAAPERQSERQRNKREGRRRRRGRDTGRDHGFER
>NZ_CP010855.1|WP_048531329.1|1533031_1533391_-|hypothetical-protein
MTEIKRTDQTKRSLQEELLRVRTQADEIEKASGSGEDTQRVVLTLPKSLVHMAEFIAIMETRPMPEALDFWNYVSGIGSDDPMPTRNAKRIMRAWMEEEIMTRTHVAMLELQAEAKDRK
>NZ_CP010855.1|WP_048531343.1|1542953_1543769_-|lytic-murein-transglycosylase
MRRFTIVFSIVAGLAAPAVEAAQCITSKGAFSGYKAGLAQDAQASGVGPRGMQALQSAQLSGITWRFESNPSSQSGTLQRDPATFLAKRSGSSADAFIQRTRSRMAKNPNTFASIEQRFGVPGSVLATIWGLETSWGGYLGETPIVGGAVTLASYCRRHPRFESHAIAALQLVDRGIITANTRGGPSGELGHMQFLAGNWLRYGVDGNGDGRADPYNAVDALASAANMLARNGWRAGAPFGQGTANFRVLSAWNDSGNYQRAIAYAAERVQ
>NZ_CP010855.1|WP_048531345.1|1543940_1545347_-|type-I-glutamate--ammonia-ligase
MSAKDLLKLIKDEDVAYVDIRFTDPRGKLQHVTVIESEVDEDFLEEGFMFDGSSIAGWKSIEASDMKLMPDCDSAYIDPFYAEKTVCVHCSVVEPDTNEPYNRDPRGTAEKAEAYLKSSGIGDISYWGPEAEFFLFDDVRFSNSINKVSYEVDALDASWNTDTEYEMGNTGHRPGIKGGYFPVNPIDDGQDIRSEMLSTMKRLGMKVDKHHHEVASCQHELGLIFGSLTKQADELQKYKYVIHNVAQAYGKSATFMPKPIYGDNGTGMHCNMSIWKDGKPLFAGDKYADLSQEALYFIGGILKHAKALNAFTNPSTNSYKRLIPGFEAPVLRAYSARNRSGCVRIPWTENPKAKRVEARFPDPSANPYLCFAALLMAGLDGITNKIDPGEAMDKNLYDLPAEELEGIPTVCGSLREAMQELQADMDFLLAGDVFTKDQIEGYIELKMEEIELYEHTPHPVEFGMYYSC
>NZ_CP010855.1|WP_048531347.1|1545464_1545803_-|P-II-family-nitrogen-regulator
MKKIEAIIKPFKLDEVKEALQDVGVQGLSVVEVKGFGRQKGHTELYRGAEYVVDFLPKVKIEVVLDDDQVDGAIEAIVEAAKTDKIGDGKIFVTPVEQAIRIRTGETGSDAL
>NZ_CP010855.1|WP_048531349.1|1545970_1547578_+|bifunctional-ADP-dependent-NAD(P)H-hydrate-dehydratase/NAD(P)H-hydrate-epimerase
MSELLTGAEMRALEQAAIARGDVTGLELMERAGAGVVRAVLETWPGIWPGIWPELGQGAPRAVVLCGPGNNGGDGFVIARLLLARGWAVEVFLLGDPEKLPPDARANHDRWHALGAVRPLEETSLDGYLEAHPETALAVDALFGTGLTRPLRDLRGVQAVLSRWQAAAAPQVVAVDLPSGLCSDSGRYLGWDRDDPPGSVVRANLTVSFHRPRLGHLLAEGPEACGALVVQDIGLAPSQDAVPGPARRVDAPPAETLAKGGGHKFSHGHAVVISGGFGKTGAARLAARGALRIGAGLVTLGVPGAAQMEVAGQITGLMMTRVEDGAALAALLEDGRITALCLGPGLGLDRARALVPLALDQVAERARPARGVVLDADALTAYRDDPEALFARLHARCVLTPHDGEFARLFPDLAARLGDTPHAGPAYSKADAARDAARRAGCVVVFKGPDTVIADPQGRVAVNAGVYDRAAPWLATAGTGDVLAGFVTGLLARGMAPMPAAQTAAWLHVACAWHFGPGLISEDLPEALPAVLRAL
>NZ_CP010855.1|WP_082154444.1|1547574_1548096_-|Hint-domain-containing-protein
MNPNVVGRASEQVAQPDLVRHPERANSEINGLIAGTRLWTLDGEMPVQYLSPGDRIITRDTGMALLRQVVLREVRCATVRIRAGSLGHTRPDTDLVLAASQPVLVRDWRAEALFGAKEVLVPAARLVDGQFITRGGHEKLRLIELHFDTPHILYADGIEIACGTRQPTALGVA
>NZ_CP010855.1|WP_048531351.1|1548372_1549263_+|DUF2520-domain-containing-protein
MTRPLSITVIGPGRVGQTLLRLGHSSGVFELAEILARRPDAAAAARDFAGGGRAITGFEDLRPADLFLLTVPDDQLAGVAGDLARQGLPPAVAAHCSGFHPAALLAPLAEAGWQTGSAHPVLSFADPASAARQFPGCFCGIEGTAADRLSEVFSTLGARCFPIRGEAKALYHAAAVISNNFTTVLQGLAQEAWAEAGVPEAVVADLHAALLRGTVENVLAKGSQAALTGPAARGDAAVVAAQGRAVTEWQAEAGAVYDLLSAMAARFKSTGRTGSGQERQPDPDRQDRQPSGDQHR
>NZ_CP010855.1|WP_048531353.1|1549194_1550124_-|AEC-family-transporter
MQALLEVILPVFLVIGAGYLAVWRRWISDGAIDGLMDFTQKIAIPVLLFQAISRLDLGAHFDLALLLSFYTGSFTGFVVGLLAGRYVFKRAWEDSVAIGFCCLFANSVMLGIAITESAYGAGALGPNYAIVALHSPFCYGLGITAMEIARSRGTPARQMPAKVLKAMFRNALVIGIMLGFVVNFSGFALPQVATDGIDLVVRAAIPCALFGMGGVMYRYRPDGDFRIIAMVCAVSLILHPTITYTMATITGLSTGALRSAVLTATMAPGINTYVFANMYGVAKRVAASSVLIATGLSILTIWVWLSLLP
>NZ_CP010855.1|WP_048533752.1|1550187_1550988_-|MBL-fold-metallo-hydrolase
MSDHYRFTILGCGSSGGVPRLGGHWGDCDPENPRNIRRRCSMLVERVGPGGITSVLIDTSPDLRSQLLDTGTGRLDGVIFTHAHADHTHGIDDLRMIVFNMKTRLPVWADGPTQDALLARFGYAFAQPEGSPYPPILDLHTIAGDVTVDGAGGPITFTPFEVNHGSIDALGFRIAGLAYVPDVAEIPEAAWPLLEGLDIWIVDALRRKPHPTHAHLARTLEWITRAAPRRAVLTNMHIDLDYATLEAETPDHITPAYDLMQLTLPA
>NZ_CP010855.1|WP_048531355.1|1550984_1551785_-|TatD-family-hydrolase
MSNPKITDSHTHLDFPDFDDARDAIVARAVEAGVHRMVTICTKLKNEPGVRALAETYDPVFYAAGTHPMSAADEPLATADALVALADHPKFVGIGETGLDYHYTSESADIQKKSLRIHIEAAQKTGLPLIIHARAADDDMAEILAAEHRNAPFSCVMHCFSSGAALAKRALDLGFYLSMSGITAFPKSAELRDIFAGAPLDRILVETDAPYLAPPPHRGKRNEPAYTAHTARKAAETFGLDYGEFAARTEANFERLFTKAAAWSPS
>NZ_CP010855.1|WP_048531357.1|1551793_1552924_-|DNA-polymerase-III-subunit-delta'
MSDDRPQPDQTEGAPHPRDTARLLGQAAAEQAFLAAVTSGRLHHGWMIAGPRGTGKATLAWRIARHLIAHPPGAADDGLFGAPPPRSLDIPEDHPVARRIAAGSEPGLFKLTRPWDDRAKRLKAEITVDEVRKLKSRFALSAADGGWRVVIVDAADEMNTSAANALLKLLEEPPARATLLLVTHQPSALLPTIRSRCRMLHLRPLSPPDMAAALDQAGVAVPPEEAEALAALSAGSVGDAIRLSLNEGPKLYTAILTLLGSLPQLDRARALALAEAATARGAEDRVNTIFSLLDLALIRLARAGASGQMPQPAAARNEAEIFARLAPDLRRARAWAEIGQQISERSRHGRAVNLDPAALILDTMIKLQKTASDLAA

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Crispr_ID: NZ_CP010855_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP010855_2

1702631-1704252

TypeII

Consensus_repeat	Method
NNNGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CRT
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	PILER-CR
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CRISPRCasFinder

24 spacers

cas2,cas1,cas9

The CRISPR arrays of NZ_CP010855_2

>merge|NZ_CP010855|2|1702631-1704252|CRT,PILER-CR,CRISPRCasFinder
CGGAAACAGTCGGGGCGACCACCTCTCAGCTAAACTGTTCTGCCACGCCTTGAGGAACCGGCGGAGGTTGCGGCTGGACCTCGAATTCTGAACAGCTAAACTGTCGGCCACCCAGACCGTTACCCGGTCGGTGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTTACTACGGACATGGCCCCGACGCCGATCACGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTATCGAGATCGGCGACCAGGGTCAGCGTCGAGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTTGTCCCTGACAAGTGTCCCTGGTTCATCATGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTCATGCTGGGGAACCTGCCACGCGACTGCCAGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTCTGCGGGTCCATCGGCTGATAGTAGCGATCGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTCTTCATCGACTATTACGAGGCAGTCGGGCAGGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTGTTCGAAAGGGACAGCTTGACGCCGGAGTTTGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTTCTGGGCACCCACACCAAGAATGCACAGGAGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTGAGCAGGACAAACTAGCAGACATCTTGAAGGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTCCTCGCTGGCTACGGCAGCGACTGCACGGTGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTTCCGCGTTTGACGGGTCGAGAACGGGCAGGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTCCGCGCGGCCATCGGATCGAGTGCAGCCAGGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTGACGTGGTGCGCGACATGGAAATGCGGGTCGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTCCTGGACTACTGCAAGCGGGCTGGCGTGATGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTGTATCGCCCTCATAGGTCAGGGTTACAGCCGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTGAGCTGCGCCGACTGGACGCCAGCGAGGCAAGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTCGGGTGACACCTTGTCCAGCGCCTCATCAGGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTTGGGCCGTGACGCGCTGCGACAGAAAATGGGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTGTCACTCAGAATGACCCGCTCACCGATCCCGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTGCGCTTGAACAGCAAAAAGAGCATGCCAGGGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTGCACTTGCCGAGGCTGAGGCGCAACTTTCCGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACTATACTCCTCTTCGGAGTCGAGCATCAGCGTGTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT

>NZ_CP010855|2|1|1702631-1704252|CRT
CGGAAACAGTCGGGGCGACCACCTCTCAGCTAAACT	GTTCTGCCACGCCTTGAGGAACCGGCGGAG
GTTGCGGCTGGACCTCGAATTCTGAACAGCTAAACT	GTCGGCCACCCAGACCGTTACCCGGTCGGT
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	TACTACGGACATGGCCCCGACGCCGATCAC
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	ATCGAGATCGGCGACCAGGGTCAGCGTCGA
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	TGTCCCTGACAAGTGTCCCTGGTTCATCAT
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CATGCTGGGGAACCTGCCACGCGACTGCCA
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CTGCGGGTCCATCGGCTGATAGTAGCGATC
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CTTCATCGACTATTACGAGGCAGTCGGGCAG
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GTTCGAAAGGGACAGCTTGACGCCGGAGTTT
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	TCTGGGCACCCACACCAAGAATGCACAGGA
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GAGCAGGACAAACTAGCAGACATCTTGAAG
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CCTCGCTGGCTACGGCAGCGACTGCACGGT
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	TCCGCGTTTGACGGGTCGAGAACGGGCAG
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CCGCGCGGCCATCGGATCGAGTGCAGCCAG
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GACGTGGTGCGCGACATGGAAATGCGGGTC
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CCTGGACTACTGCAAGCGGGCTGGCGTGAT
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GTATCGCCCTCATAGGTCAGGGTTACAGCC
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GAGCTGCGCCGACTGGACGCCAGCGAGGCAA
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CGGGTGACACCTTGTCCAGCGCCTCATCAG
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	TGGGCCGTGACGCGCTGCGACAGAAAATGG
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GTCACTCAGAATGACCCGCTCACCGATCCC
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GCGCTTGAACAGCAAAAAGAGCATGCCAGG
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GCACTTGCCGAGGCTGAGGCGCAACTTTCC
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	ATACTCCTCTTCGGAGTCGAGCATCAGCGT
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT

>NZ_CP010855|2|1|1702697-1704252|PILER-CR
GTTGCGGCTGGACCTCGAATTCTGAACAGCTAAACT	GTCGGCCACCCAGACCGTTACCCGGTCGGT
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	TACTACGGACATGGCCCCGACGCCGATCAC
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	ATCGAGATCGGCGACCAGGGTCAGCGTCGA
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	TGTCCCTGACAAGTGTCCCTGGTTCATCAT
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CATGCTGGGGAACCTGCCACGCGACTGCCA
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CTGCGGGTCCATCGGCTGATAGTAGCGATC
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CTTCATCGACTATTACGAGGCAGTCGGGCAG
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GTTCGAAAGGGACAGCTTGACGCCGGAGTTT
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	TCTGGGCACCCACACCAAGAATGCACAGGA
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GAGCAGGACAAACTAGCAGACATCTTGAAG
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CCTCGCTGGCTACGGCAGCGACTGCACGGT
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	TCCGCGTTTGACGGGTCGAGAACGGGCAG
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CCGCGCGGCCATCGGATCGAGTGCAGCCAG
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GACGTGGTGCGCGACATGGAAATGCGGGTC
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CCTGGACTACTGCAAGCGGGCTGGCGTGAT
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GTATCGCCCTCATAGGTCAGGGTTACAGCC
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GAGCTGCGCCGACTGGACGCCAGCGAGGCAA
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CGGGTGACACCTTGTCCAGCGCCTCATCAG
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	TGGGCCGTGACGCGCTGCGACAGAAAATGG
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GTCACTCAGAATGACCCGCTCACCGATCCC
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GCGCTTGAACAGCAAAAAGAGCATGCCAGG
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GCACTTGCCGAGGCTGAGGCGCAACTTTCC
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	ATACTCCTCTTCGGAGTCGAGCATCAGCGT
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT

>NZ_CP010855|2|2|1702697-1704252|CRISPRCasFinder
GTTGCGGCTGGACCTCGAATTCTGAACAGCTAAACT	GTCGGCCACCCAGACCGTTACCCGGTCGGT
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	TACTACGGACATGGCCCCGACGCCGATCAC
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	ATCGAGATCGGCGACCAGGGTCAGCGTCGA
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	TGTCCCTGACAAGTGTCCCTGGTTCATCAT
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CATGCTGGGGAACCTGCCACGCGACTGCCA
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CTGCGGGTCCATCGGCTGATAGTAGCGATC
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CTTCATCGACTATTACGAGGCAGTCGGGCAG
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GTTCGAAAGGGACAGCTTGACGCCGGAGTTT
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	TCTGGGCACCCACACCAAGAATGCACAGGA
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GAGCAGGACAAACTAGCAGACATCTTGAAG
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CCTCGCTGGCTACGGCAGCGACTGCACGGT
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	TCCGCGTTTGACGGGTCGAGAACGGGCAG
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CCGCGCGGCCATCGGATCGAGTGCAGCCAG
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GACGTGGTGCGCGACATGGAAATGCGGGTC
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CCTGGACTACTGCAAGCGGGCTGGCGTGAT
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GTATCGCCCTCATAGGTCAGGGTTACAGCC
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GAGCTGCGCCGACTGGACGCCAGCGAGGCAA
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	CGGGTGACACCTTGTCCAGCGCCTCATCAG
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	TGGGCCGTGACGCGCTGCGACAGAAAATGG
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GTCACTCAGAATGACCCGCTCACCGATCCC
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GCGCTTGAACAGCAAAAAGAGCATGCCAGG
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	GCACTTGCCGAGGCTGAGGCGCAACTTTCC
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT	ATACTCCTCTTCGGAGTCGAGCATCAGCGT
GTTGCGGCTGGACCCCGAATTCTGAACAGCTAAACT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP010855.1\|WP_048531581.1\|1698118_1699936_+\|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	unknown
NZ_CP010855.1\|WP_148562848.1\|1711837_1712494_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010855.1\|WP_048531601.1\|1715321_1715645_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010855.1\|WP_048531578.1\|1695437_1695875_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010855.1\|WP_048531576.1\|1694850_1695441_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010855.1\|WP_048531605.1\|1716653_1717136_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NZ_CP010855.1\|WP_048531595.1\|1704666_1705578_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_CP010855.1\|WP_148562847.1\|1701760_1702207_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010855.1\|WP_148562846.1\|1695852_1698105_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372253
NZ_CP010855.1\|WP_148562850.1\|1714990_1715227_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010855.1\|WP_048531583.1\|1699935_1700697_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010855.1\|WP_048531585.1\|1700774_1701320_+\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|177282
NZ_CP010855.1\|WP_048531597.1\|1705631_1708844_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187774
NZ_CP010855.1\|WP_048531593.1\|1704325_1704631_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP010855.1\|WP_048528913.1\|1710060_1711266_+\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|307151
NZ_CP010855.1\|WP_048531607.1\|1717281_1718232_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293840
NZ_CP010855.1\|WP_048531574.1\|1694164_1694854_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010855.1\|WP_082154582.1\|1701470_1701764_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010855.1\|WP_048531591.1\|1702181_1702466_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP010855.1\|WP_148562849.1\|1712495_1714802_+\|UvrD-helicase-domain-containing-protein	unknown	unknown	gnl\|CDD\|223288

Protein	Function_ID	Function_description	E-value
NZ_CP010855.1\|WP_048531585.1\|1700774_1701320_+\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|177282	PHA00447, PHA00447, lysozyme.	8.4253e-43
NZ_CP010855.1\|WP_048531597.1\|1705631_1708844_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|187774	cd09643, Csn1, CRISPR/Cas system-associated protein Cas9. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Very large protein containing McrA/HNH-nuclease related domain and a RuvC-like nuclease domain; signature gene for type II.	1.46671e-73
NZ_CP010855.1\|WP_048531593.1\|1704325_1704631_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	9.64034e-25
NZ_CP010855.1\|WP_148562849.1\|1712495_1714802_+\|UvrD-helicase-domain-containing-protein	gnl\|CDD\|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	0.000151368
NZ_CP010855.1\|WP_048531607.1\|1717281_1718232_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293840	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	1.86644e-59
NZ_CP010855.1\|WP_048531595.1\|1704666_1705578_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	6.61124e-79
NZ_CP010855.1\|WP_048531605.1\|1716653_1717136_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	1.84916e-15
NZ_CP010855.1\|WP_048528913.1\|1710060_1711266_+\|IS256-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	1.82878e-143
NZ_CP010855.1\|WP_148562846.1\|1695852_1698105_+\|hypothetical-protein	gnl\|CDD\|372253	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family.	0.00149544

>NZ_CP010855.1|WP_048531591.1|1702181_1702466_+|hypothetical-protein
MLQFINSIEPEAWVGLAGLLAGIGGAIAAGFRGVQKNPPQVGTGPPPTDRTEYVLTETRRANATLTQIDERMTEIDHRTENMAADLRVLLDRKH
>NZ_CP010855.1|WP_148562847.1|1701760_1702207_+|hypothetical-protein
MTVHVSIADSLLQNGRALEWLTSGIILTFACTLALPGDTLATSPTFGAFVALGADEAALVLPLTFIAAMRMAGLWINGNWRRSPLLRCVGAVLGAGIFMGLAVLFAVPFLGGQTGALTTGVGTYFVLAAFDILAAYRSAADAAVHQFD
>NZ_CP010855.1|WP_082154582.1|1701470_1701764_+|hypothetical-protein
MNRAAGAFEAATGLRIDEGHRRALHSAIRSGIEAALEDGPEAGLDEIKAASVDYAHRSVPGAIRALVPGEGVLDALALRYYREAMQRAGLPAPELML
>NZ_CP010855.1|WP_048531585.1|1700774_1701320_+|N-acetylmuramoyl-L-alanine-amidase
MRKITEIIVHASATRPAWLARRPITDKLAEIRRWHTLDRGWSDIGYHLLIDRDGTVAAGRPLERTGAHVRGRNTGTIGLCLIGGHGAAETDAFHDNFTLQQNAALKAQIALLQARFGALRVTGHNQYAAKACPGFLLPQWLATGGDTQALEAPTERATEAARLRWRLAEIRDTAASALGNA
>NZ_CP010855.1|WP_048531583.1|1699935_1700697_+|hypothetical-protein
MSTILRAKGNVIAPDGIDSPHQDGLLLSHVFCDLTDGYFHRNFAPGQPDSEIYGTVAPSLSGTAARFTGLSNFIQSKILEPRVGTVLMVASTVDSLADDANRPMFFGTWTGTPRGEATASTTFGLYSRITSASSPNVVRMGAGRGTSVADDVNGDCALLANDVSAPHIYSMTFSEAGPNAAEDHTEGVTASDDSTAPRFPTDQMVRIGSGYAQYTGICDLSIIRLWGKVLTPAAIAEEVAHAEAFMARLGVAV
>NZ_CP010855.1|WP_048531581.1|1698118_1699936_+|SGNH/GDSL-hydrolase-family-protein
MLETTETPRAVWRGNPVQSDHQPDPERIVALLEEILALAASTADLSLVTGALSWQGVWDAAANSPAIPAAAAGNSGYLYWVGTAGSTNLDGITDWAVGDYVVSDGSSWNRIRIDVGVLSIGGKSGTVTLEAADIDDSSAAGRALLQAADAAAQRVALEITAMEQVEDDATGKAELIASDENGFTFFRAGEDRIVGAGMLAERGGDRTMITDLRGFQYDDRAPAPSVTAPLLPQRLFGVTGVEFGLHRDGLLEDRDTEARMLLSGATGLQLEGQEMLRCDLSGLGVSATVSLRATTCRARYGEQSITVHAAPQSPGTGNAPAVLLVGDSITHRGSGAMLDYWLGTWGYVPSFIGTLTGEAETDPADGAMALPATLGEGKPGHALADLTYLFTGRVSPLAPGSEATFDGETVENKRLYNTMIRVASGEPAADQRNGYVLDFANYISRHGLATPDMLVIGYGTNDIRDAGIDVIRDHFFDEYSLVFRRWFASYPSKHVVVWMPGTAADFTRSRVWTNAYAPALKGLIAAATAETVANAGSGEVLVVPAWAMAAHGAGYDLSASTETVDADTGGVLRQIEDTIHPTAGTRFATLKSVAAAIACAIQGEI
>NZ_CP010855.1|WP_148562846.1|1695852_1698105_+|hypothetical-protein
MPIKQLRKRALAMALVCSTALTAPSQAAAEPVTLFFQGFLAATGFYGAAGGAVATALGGAAAAGAAVGGFLFGTLAGRVLLSLALSAVVNLLTPQPEIPRPSAQFANYVQPISPFERVYGEVKKGGVVAFRSGIRDKQKHMVITVAAHPCEGPQAHFLDLREVTLAKGSAFDGVMLDHEVITKPYKFDDPPRSRVSIRPFTGGAGQAADPILVSTFTEFTAAHDFAGHSGVAYYCREVPQEDFLEVYPSGREAVYTGIWRGWSEIYDPRIDDTGYSNNWALGLAHELVNVWGLSVDWDRVAVEADICDALVTNGDGGTQKRWTFNHTFTDDQDFQTVIAQFLGAADGYLWQRPDGKVDFYAGRWLAPTLALEARDFFSCQVVDGNQGLNPRTEYWAEYREPDNGYRETPSAAWVVDAEAGRNAQQLALYPIDSHNQVLRVLKPLARAERARFKITGTIGLIGYELIGGRDNDAGGTAGLAHRFVTVSHPVLGEEVICEVAKVERLAGGNSFTVELISTAEEDRQFVAATEEPARPSYNAADVEGDDPIDTIDDLAGTAVSGTGGVAQINWTWTAPDSSLSPDLRLREQGGDWQLVSLPSGTGSFLQTGLIDGATYQAEIRSRHRSNRVGEWRPLTPVEVVAIADTTPPGAHVSGSFALSETGGDVTVSFEAPNDAPYHATRILRADYASAPGSYDIADASLIRLEYGLPGQVDSWEDSAVAAGHHAYWIEPINASGVAGPVSGPETIDTV
>NZ_CP010855.1|WP_048531578.1|1695437_1695875_+|hypothetical-protein
MNLLSLTLQRWTARPHVWGQDDCILAPLDWVSAVKGDGVDLAAGLRLTYEDFASAQKAYRFFTDPLPLAEDYLERRAGLSRVAEVRRGDVALFKYPGQGGRILPTAGICVGPQLFACRADPGVLAARPGTLIAAWGVGYADQTTA
>NZ_CP010855.1|WP_048531576.1|1694850_1695441_+|hypothetical-protein
MSFFPEGYDPRDPVGGLLHLVEADTPDGTHRFLLHTEGVFTDTSGKKWVGSEMVRDEALGFGIGGTAKASSMTLGFIEDPADEFDLIGKLRELGADYVKGYALRRYVQPIGAISELYAPQFAPQQVAEEVMDHLTFNAPDALNRSITLHLEGAFRVRGGAARRVYNTTDHARQLGAPNPSYEFIPTEPREEKVFGS
>NZ_CP010855.1|WP_048531574.1|1694164_1694854_+|hypothetical-protein
MQREIVDVPRGLLRLLEVDWDIDWRAQGLRDSADGVSTAVINRFPRWSGSPRVVLSGERLRAWRAIRAEAQGLVGLYRVPMVDPVGYRPQAAAEAAGIAATGVPFSTGEVFSHGQGFAFDPVALATAGFAAGAREITLDTATAGGFPKVGQILSHDDRPFMVTAILATSGTECTIRIQLPLRADLPAGGRVQMQARGIFQAAEQQMGNPSYGRDQVSRVRLSFQEVLNR
>NZ_CP010855.1|WP_048531593.1|1704325_1704631_-|CRISPR-associated-endonuclease-Cas2
MWILVMFDLPTDTKPQRKAATDFRNFLLDEGFERSQFSVYARFVNGKEAFQTRVNRIERHLPDKGDIQILNFTDRQYRDIVHFSDQGRRAARKNPEQLALF
>NZ_CP010855.1|WP_048531595.1|1704666_1705578_-|type-II-CRISPR-associated-endonuclease-Cas1
MDQIVDITTDGRHLSRARGFLIVSEGSEEIGRIPLDHVAGVIVHAHGTTWSTSLLTELADRGAPVVLCGSNHAPRSVLLPLEGHHAQGARLRAQWQAKAPLFKQGWKQVVISKIAMQAAALEAVGETHAPVAMLKRKVASGDSTNVEAQAARYYWPRMMGQDFRRDRTAHDLNALLNYGYTVLRAATARAVVAAGLHPTIGLHHSNRGNAFALADDLMEPFRPLVDCCVRGLAERNGPEVDTEAKTTLARLIALDLPLGGGLTPVSVALGKLAVSLGQSFETGRLNLALPSPPDALTLAGLGS
>NZ_CP010855.1|WP_048531597.1|1705631_1708844_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MRLGLDIGAASIGWWLYETEGQGTSTRITRVIDGGVRIFSDGRDPKSKASLAVDRRAARAMRRRRDRYLRRRASLMKVLSRSGLMPSDPAEAKPLELLDPYALRAQGLDQALPLTHFGRALFHLNQRRGFKSNRKTDRGDNENGKIKDASQRLDWAMHEAKARTYGEFLHLRRQKAPDPRQVPTVRTRLSVGKRGGPDAKEEAGYDFYPDRRHLEEEFHELWSAQAQFHPELTQDLRDLVFEKIFYQRPLKEPKVGLCLFTSEERLAKAHPLTQRRVLYETVNQLRITADGRSVRPLSREQRDQIILALDTKKPTKSLNSMVVTLQALGKVLKLREGERFTLESGVREAIACDPVRAAMLATFGPRWSALDWPEQWQVISRVRKLQDDKDFAELVEWLIELYGVDKEAAVKIANTHLPEGYGRLGLTATTRILDRLKSNVFTYAQAVAACGWHHSDQRTGECLDRLPYYGAVLDRHVIPGTYDENDDDITRFGRITNPTVHIGLNQLRRLVNKIIEVYGKPNQIVVELARELKQSEQQKNDAIKLIRDTTTAAKQRSEKLEELGITDNGRNRMLLRLWEDLNPDDAMRRFCPYTGQRISAAMIFDGSCDVDHILPYSRTLDDGFANRTLCLREANREKRNQTPWEAWGGTPNWEAIETNLKNLPENKRWRFAPDAMARFEGENDFLDRALVDTQYLARISRTYLDTLFTEGGHVWVVPGRLTEMLRRHWGLNSLLTDKDRGAVKSKNRTDHRHHSIDAAVVAATDRSLLNRISRAAGQGEVAGQSAELIARETPPPWEGFRNDLKSQLGRIIVSHRADHGRIDRQARKQGRDSTAGQLHQETAYSIVDDTRVASRIDFLSVKPAQLLDQPGRSGQVRDLQLRKALRVATGDLTGKDYEKALRDFAAKPGPYKGIRRVRIIKPLQEQARVPVPVLDPIKAYQGGSNHVFEIWHLPDGKVEPQVITSFEAHALEVEKRPHPAAKRLLRVHKGDMVALKREGRTVVGHVQQMHIKNGLFIVPHNEANADARNSDRTDPFKWIQIAAQPAIAAGIRRVAVDEIGRLRDGGAKTI
>NZ_CP010855.1|WP_048528913.1|1710060_1711266_+|IS256-family-transposase
MTKTNMDLSELLQKQDGGDFLRAVAEAVLQLIMEADVEGLIGAGKHERADQRTTWRNGYRQRALDTRLGTLNLKVPKLRQGSYFPGFLEPRKTSEKALVAVIQEAWIGGVSTRRVDELAQAMGLQGISKSTVSKLCKDIDERVGEFLNRPLSGEWPYVWLDATYLKVRQGGRIVSVAAIIAVAANTDGRREIIGLGLGPSEAETFWMDFLRGLKARGLDGTKLVISDAHSGLRAAIERVFEATWQRCRVHWMRNALAHVSRGQHTVVAAAIRQAFDQPDRKHAGETWRHVAEQLRTRWPKLADLMDESEHDVLAYMGFPRQHRTKLHSTNPIERLNKEVKRRADVVGIFPNEASIIRLIGAVLFEQNDEWQTASRYMMVEAFAEIDAEETDPILSITTQAA
>NZ_CP010855.1|WP_148562848.1|1711837_1712494_+|hypothetical-protein
MLEAELSEQDGNIRKMLRDASIPESMPKAVSLRIIANTHFPLDEGSKKERDKSKRFHELITSFDSFLGVQSGSPDDIYAWFAKNKPAKISELIKRLSKHAVAGHYLLEYLSDDEENASGYVCLLREVSTIPRFIAERIAEGLDSQTHSELIAEADSKVSSLVIDHGDMAMPVSEIASPVIEHILQSFSLLYGRIGIADPHKPTIQLLEKSCLQQPEGA
>NZ_CP010855.1|WP_148562849.1|1712495_1714802_+|UvrD-helicase-domain-containing-protein
MKYICIDDGAVAELISGREYQSVDFDDGEKLIRSLSGLGAFLIGDRVITHFQDSDGVFLTTSGSWKNKKYLVIDCDQSKLFNQLPKSDSLTSFQKMLRFCSKMWSNGLFNKSERIITGTTKAIIFPLNYAANSGFRIAIERDPHSERLSKRDMRGQFLLVYKSGSVGADSATETADETNFRKVFERLPEVYRHVQTVSEQRKTENHANGQMASTALHAAPNAKHSAFLPFEDWMPILTAQQRSFVHSPFGSAHRLQGPAGTGKTLALMLRTVECLRQAERKKEQCNALIVTHSEATRQSIKASLSAIDQNNFQDRDRKAEKVSLSVETLASLCGRFLSQTISESEFIDRDAQDSKILQRFYIEEAIVRARELDYAAYNPHLSVELRDLLDGAEVESLAPLFQHEISILIKGRAGDSFEAYKNCPALTFGLPVRNDADKGFVFAIFERYQDQLADNSQFDTDDVVISAVGQLDTPIWRRRRTREGFDLIAIDETHLFNINELHVFHHFTRANDQLPISFTVDQAQAVGDRGWGSVESFFDSMSEVPNQKVKRTELSAVFRSSPAIRDFCHSILASGATLFSNFTDTLNQSQSAFTAEEERRSQPIIYSEYADDDTLISSAFEKAEMLMAETESSKSQVLITSLDDNLIEKMQEYARSRNKPITYLDRRGDYTTVRQAEKSGHVVLGHADFVGGLEFNVVVVVGVDKGRVPKEGESIDSNSRSFSSYVAHNRLYVAASRAKFALHLCGVKSRGSSKLLDVAFTNGIISAE
>NZ_CP010855.1|WP_148562850.1|1714990_1715227_-|hypothetical-protein
MAKAAIQTLSELNHLAALDAKVSDEQGADSNKLRLVPDTRRSAIYDQARPAFDNPGASGNRKAEQNDIAGRDIGGPAG
>NZ_CP010855.1|WP_048531601.1|1715321_1715645_-|hypothetical-protein
MTPVVLLIGRLPSVEETVARELEEFPVQWLGAHNREEVIAQLEREPGIAVVVMGAGLDDRSRGELIGVIASHRPDLSIHVKDRASGPAGMAPFVRRVVRAELLSEPA
>NZ_CP010855.1|WP_048531605.1|1716653_1717136_-|MarR-family-transcriptional-regulator
MPMESFDLSTFLPYRLAILSERISRRLALEYGRSHGISVPEWRVLVHLARSKQASVREIHSYANLEKPRVSRTVAKLQAAGMVRKVTGKQDSRLVEISLTEKGQTVLGEILPAALEFEDRLVQALSAEEHAMCIEIAEKLHAVLDDDPLAPMRSQLDTPD
>NZ_CP010855.1|WP_048531607.1|1717281_1718232_+|MBL-fold-metallo-hydrolase
MAKAFASQGDTSEKEISFTEIGEGLFAFTAEGDPNSGVIIGDDSVMIVEAQATPRLANKVIDCVRSVTDKPITHVVMTHYHAVRVLGASAFDAQQVIMSDKARAMVVERGQEDWDSEFQRFPRLFEGHESIPGLTWPTTTFNDQMTVYLGNRKVEIKQIGRAHTAGDSVIWVPDAQCMFTGDIVEDHSACYCGDGHFEDWGGTLDAVKAYDPQSIAPGRGGALIGREAVESAIASTRDFVESTYLPAKQVAARGGSLKDAWDAVREACDPKFKDYAIYEHCLPFNVSRAYDEARGIDTPRIWTAERDVAMWEALQD

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP010855_2	2.2\|1702733\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1702733-1702762	30	NZ_CP005961	Pseudomonas mandelii JR-1 plasmid unnamed, complete sequence	154567-154596	3	0.9
NZ_CP010855_2	2.14\|1703526\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1703526-1703555	30	NZ_CP054603	Sulfitobacter pseudonitzschiae strain H46 plasmid unnamed4, complete sequence	57426-57455	4	0.867
NZ_CP010855_2	2.4\|1702865\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1702865-1702894	30	NZ_CP038238	Leisingera sp. NJS201 plasmid unnamed4, complete sequence	119997-120026	5	0.833
NZ_CP010855_2	2.12\|1703395\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1703395-1703424	30	NC_047804	Ralstonia phage RS-PII-1, complete genome	39460-39489	5	0.833
NZ_CP010855_2	2.13\|1703461\|29\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1703461-1703489	29	NC_011984	Agrobacterium vitis S4 plasmid pAtS4c, complete sequence	143857-143885	6	0.793
NZ_CP010855_2	2.15\|1703592\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1703592-1703621	30	NZ_CP017105	Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence	791509-791538	6	0.8
NZ_CP010855_2	2.15\|1703592\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1703592-1703621	30	CP006880	Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602c, complete sequence	964146-964175	6	0.8
NZ_CP010855_2	2.23\|1704121\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1704121-1704150	30	CP008938	Candidatus Caedibacter acanthamoebae plasmid Plasmid_00002, complete sequence	31953-31982	6	0.8
NZ_CP010855_2	2.3\|1702799\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1702799-1702828	30	NZ_CP022191	Yangia pacifica strain YSBP01 plasmid unnamed1, complete sequence	489310-489339	7	0.767
NZ_CP010855_2	2.4\|1702865\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1702865-1702894	30	NZ_CP042332	Bosea sp. F3-2 plasmid pB32-1, complete sequence	196264-196293	7	0.767
NZ_CP010855_2	2.4\|1702865\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1702865-1702894	30	NZ_CP039694	Agrobacterium larrymoorei strain CFBP5473 plasmid pTiCFBP5473, complete sequence	136451-136480	7	0.767
NZ_CP010855_2	2.4\|1702865\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1702865-1702894	30	NZ_CP016080	Mesorhizobium loti NZP2037 plasmid pML2037, complete sequence	120664-120693	7	0.767
NZ_CP010855_2	2.4\|1702865\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1702865-1702894	30	NZ_CP015867	Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence	372333-372362	7	0.767
NZ_CP010855_2	2.4\|1702865\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1702865-1702894	30	AP022674	Sphingomonas sp. HMP9 plasmid pHMP9 DNA, complete sequence	38426-38455	7	0.767
NZ_CP010855_2	2.9\|1703196\|31\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1703196-1703226	31	MH697589	Microbacterium phage Neferthena, complete genome	39530-39560	7	0.774
NZ_CP010855_2	2.13\|1703461\|29\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1703461-1703489	29	KM389227	UNVERIFIED: Pseudomonas phage F_MX1987sp/MX560 clone contig00003 genomic sequence	5894-5922	7	0.759
NZ_CP010855_2	2.14\|1703526\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1703526-1703555	30	MG214783	Sinorhizobium phage HMSP1-Susan, complete genome	6036-6065	7	0.767
NZ_CP010855_2	2.14\|1703526\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1703526-1703555	30	NZ_LR134452	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 10, complete sequence	258487-258516	7	0.767
NZ_CP010855_2	2.22\|1704055\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1704055-1704084	30	KY984068	Erwinia phage vB_EamM_Y3, complete genome	161511-161540	7	0.767
NZ_CP010855_2	2.24\|1704187\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1704187-1704216	30	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	259352-259381	7	0.767
NZ_CP010855_2	2.3\|1702799\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1702799-1702828	30	NZ_CP042998	Aquisphaera giovannonii strain OJF2 plasmid pOJF2_1, complete sequence	56155-56184	8	0.733
NZ_CP010855_2	2.4\|1702865\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1702865-1702894	30	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	1398932-1398961	8	0.733
NZ_CP010855_2	2.4\|1702865\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1702865-1702894	30	MN582054	Microviridae sp. ctYqV29, complete genome	2818-2847	8	0.733
NZ_CP010855_2	2.4\|1702865\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1702865-1702894	30	KF024728	Mycobacterium phage Muddy, complete genome	12331-12360	8	0.733
NZ_CP010855_2	2.4\|1702865\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1702865-1702894	30	CP000877	Herpetosiphon aurantiacus DSM 785 plasmid pHAU02, complete sequence	8240-8269	8	0.733
NZ_CP010855_2	2.4\|1702865\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1702865-1702894	30	MN908690	Microbacterium phage Hubbs, complete genome	24389-24418	8	0.733
NZ_CP010855_2	2.4\|1702865\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1702865-1702894	30	MN096374	Microbacterium phage Roman, complete genome	24237-24266	8	0.733
NZ_CP010855_2	2.4\|1702865\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1702865-1702894	30	MK919474	Microbacterium phage Lupine, complete genome	23591-23620	8	0.733
NZ_CP010855_2	2.6\|1702997\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1702997-1703026	30	NZ_CP017148	Bosea vaviloviae strain Vaf18 plasmid unnamed1, complete sequence	110913-110942	8	0.733
NZ_CP010855_2	2.8\|1703129\|31\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1703129-1703159	31	NC_006552	Pseudomonas phage F116, complete genome	24821-24851	8	0.742
NZ_CP010855_2	2.8\|1703129\|31\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1703129-1703159	31	AY625898	Pseudomonas aeruginosa phage F116, complete genome	24821-24851	8	0.742
NZ_CP010855_2	2.8\|1703129\|31\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1703129-1703159	31	LT603684	Pseudomonas phage phiC725A genome assembly	25152-25182	8	0.742
NZ_CP010855_2	2.14\|1703526\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1703526-1703555	30	MK376343	Pseudomonas sp. strain ANT_J16 plasmid pA16J1, complete sequence	27752-27781	8	0.733
NZ_CP010855_2	2.16\|1703658\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1703658-1703687	30	NZ_CP054841	Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence	479113-479142	8	0.733
NZ_CP010855_2	2.17\|1703724\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1703724-1703753	30	NC_015969	UNVERIFIED_ORG: Enterobacter soli plasmid pENTAS02, complete sequence	9976-10005	8	0.733
NZ_CP010855_2	2.22\|1704055\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1704055-1704084	30	KT997869	Uncultured Mediterranean phage uvDeep-CGR2-AD3-C76, complete genome	8833-8862	8	0.733
NZ_CP010855_2	2.24\|1704187\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1704187-1704216	30	NZ_CP013632	Rhizobium sp. N324 plasmid pRspN324b, complete sequence	360298-360327	8	0.733
NZ_CP010855_2	2.2\|1702733\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1702733-1702762	30	NC_015184	Agrobacterium sp. H13-3 plasmid pAspH13-3a, complete sequence	237266-237295	9	0.7
NZ_CP010855_2	2.3\|1702799\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1702799-1702828	30	NZ_CP054609	Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed1, complete sequence	196558-196587	9	0.7
NZ_CP010855_2	2.12\|1703395\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1703395-1703424	30	NZ_CP045385	Ruegeria sp. THAF33 plasmid pTHAF33_a, complete sequence	760640-760669	9	0.7
NZ_CP010855_2	2.18\|1703790\|31\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1703790-1703820	31	NZ_CP020970	Xanthomonas phaseoli pv. phaseoli strain CFBP6164 plasmid unnamed1, complete sequence	5070-5100	9	0.71
NZ_CP010855_2	2.18\|1703790\|31\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1703790-1703820	31	NZ_CP023549	Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence	260143-260173	9	0.71
NZ_CP010855_2	2.19\|1703857\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1703857-1703886	30	NC_020062	Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence	174669-174698	9	0.7
NZ_CP010855_2	2.23\|1704121\|30\|NZ_CP010855\|CRT,PILER-CR,CRISPRCasFinder	1704121-1704150	30	MK433266	Streptomyces phage Shawty, complete genome	35961-35990	9	0.7

1. spacer 2.2|1702733|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP005961 (Pseudomonas mandelii JR-1 plasmid unnamed, complete sequence) position: , mismatch: 3, identity: 0.9

gtcggccacccagaccgttacccggtcggt	CRISPR spacer
ggcggccatccagaccgttaccctgtcggt	Protospacer
* ******.************** ******

2. spacer 2.14|1703526|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP054603 (Sulfitobacter pseudonitzschiae strain H46 plasmid unnamed4, complete sequence) position: , mismatch: 4, identity: 0.867

ccgcgcggccatcggatcgagtgcagccag-	CRISPR spacer
ccgcgcggccaccggatcgag-gcggcccgc	Protospacer
***********.********* **.*** *

3. spacer 2.4|1702865|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP038238 (Leisingera sp. NJS201 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.833

atcgagatcggcgaccagggtcagcgtcga	CRISPR spacer
atccagatcggcaaccagggtcagcgtgcg	Protospacer
*** ********.**************  .

4. spacer 2.12|1703395|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NC_047804 (Ralstonia phage RS-PII-1, complete genome) position: , mismatch: 5, identity: 0.833

cctcgctggctacggcagcgactgcacggt-	CRISPR spacer
cctcgctggctacggcggcgaccac-cagtg	Protospacer
****************.*****..* *.**

5. spacer 2.13|1703461|29|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NC_011984 (Agrobacterium vitis S4 plasmid pAtS4c, complete sequence) position: , mismatch: 6, identity: 0.793

tccgcgtttgacgggtcgagaacgggcag	CRISPR spacer
acctcgtttgacgggtctagaacgacaag	Protospacer
 ** ************* ******.  **

6. spacer 2.15|1703592|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP017105 (Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence) position: , mismatch: 6, identity: 0.8

gacgtggtgcgcgacatggaaatgcgggtc	CRISPR spacer
gacgtggtgcgcgagatggaaaagacgacc	Protospacer
************** ******* *  *..*

7. spacer 2.15|1703592|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to CP006880 (Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602c, complete sequence) position: , mismatch: 6, identity: 0.8

gacgtggtgcgcgacatggaaatgcgggtc	CRISPR spacer
gacgtggtgcgcgagatggaaaagacgacc	Protospacer
************** ******* *  *..*

8. spacer 2.23|1704121|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to CP008938 (Candidatus Caedibacter acanthamoebae plasmid Plasmid_00002, complete sequence) position: , mismatch: 6, identity: 0.8

gcacttgccgaggctgaggcgcaactttcc	CRISPR spacer
tctgttgccgaggctgaggagcagctttct	Protospacer
 *  *************** ***.*****.

9. spacer 2.3|1702799|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP022191 (Yangia pacifica strain YSBP01 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

tactacggacatggccccgacgccgatcac	CRISPR spacer
cagcccgggcatggccccgacgacgatccc	Protospacer
.* . ***.************* ***** *

10. spacer 2.4|1702865|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP042332 (Bosea sp. F3-2 plasmid pB32-1, complete sequence) position: , mismatch: 7, identity: 0.767

atcgagatcggcgaccagggtcagcgtcga	CRISPR spacer
cacgagatcggcgcccagcgtcagcggccg	Protospacer
  *********** **** ******* * .

11. spacer 2.4|1702865|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP039694 (Agrobacterium larrymoorei strain CFBP5473 plasmid pTiCFBP5473, complete sequence) position: , mismatch: 7, identity: 0.767

atcgagatcggcgaccagggtcagcgtcga-	CRISPR spacer
tccgagatcgccgaccagggtca-tgtagcc	Protospacer
 .******** ************ .** *

12. spacer 2.4|1702865|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP016080 (Mesorhizobium loti NZP2037 plasmid pML2037, complete sequence) position: , mismatch: 7, identity: 0.767

atcgagat---cggcgaccagggtcagcgtcga	CRISPR spacer
---gaactgcacgccgaccagggtcagcgtcgg	Protospacer
   **. *   ** ******************.

13. spacer 2.4|1702865|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP015867 (Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence) position: , mismatch: 7, identity: 0.767

atcgagatcggcgaccagggtcagcgtcga	CRISPR spacer
gtcgagatcggcggccagggccagggccag	Protospacer
.************.******.*** *.*..

14. spacer 2.4|1702865|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to AP022674 (Sphingomonas sp. HMP9 plasmid pHMP9 DNA, complete sequence) position: , mismatch: 7, identity: 0.767

atcgagatcggcgaccagggtcagcgtcga	CRISPR spacer
atcgagatcggctaccaggctcatgggccg	Protospacer
************ ****** ***  * * .

15. spacer 2.9|1703196|31|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to MH697589 (Microbacterium phage Neferthena, complete genome) position: , mismatch: 7, identity: 0.774

---gttcgaaagggacagcttgacgccggagttt	CRISPR spacer
gcagctc---tgggacagcttgacgcctgagctt	Protospacer
   *.**    **************** ***.**

16. spacer 2.13|1703461|29|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to KM389227 (UNVERIFIED: Pseudomonas phage F_MX1987sp/MX560 clone contig00003 genomic sequence) position: , mismatch: 7, identity: 0.759

tccgcgtttgacgggtcgagaacgggcag	CRISPR spacer
agcgcgttggacggatcgagaacggtgcg	Protospacer
  ****** *****.**********   *

17. spacer 2.14|1703526|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to MG214783 (Sinorhizobium phage HMSP1-Susan, complete genome) position: , mismatch: 7, identity: 0.767

ccgcgcggccatcggatcgagtgcagccag	CRISPR spacer
gccttcgtccatcggatcgagtgcagcaaa	Protospacer
 * . ** ******************* *.

18. spacer 2.14|1703526|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NZ_LR134452 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 10, complete sequence) position: , mismatch: 7, identity: 0.767

ccgcgcggccatcggatcgagtgcagccag	CRISPR spacer
gcgcgcggccagcagatcgagtgcctcgcg	Protospacer
 ********** *.**********  *  *

19. spacer 2.22|1704055|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to KY984068 (Erwinia phage vB_EamM_Y3, complete genome) position: , mismatch: 7, identity: 0.767

gcgcttgaacagcaaaaagagcatgccagg	CRISPR spacer
ctggctgaacagaaaaaagagaatgccaag	Protospacer
 .* .******* ******** ******.*

20. spacer 2.24|1704187|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.767

atactcctcttcggagtcgagcatcagcgt	CRISPR spacer
ccgcaccttctcggagtcgagcatcagcgc	Protospacer
 ..* ***..*******************.

21. spacer 2.3|1702799|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP042998 (Aquisphaera giovannonii strain OJF2 plasmid pOJF2_1, complete sequence) position: , mismatch: 8, identity: 0.733

tactacggacatggccccgacgccgatcac	CRISPR spacer
ggccgcggagatgtccccgacgccgatctg	Protospacer
 .*..**** *** **************

22. spacer 2.4|1702865|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 8, identity: 0.733

atcgagatcggcgaccagggtcagcgtcga	CRISPR spacer
gctgccgtcggcggccagggtcagcgccga	Protospacer
...*  .******.************.***

23. spacer 2.4|1702865|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to MN582054 (Microviridae sp. ctYqV29, complete genome) position: , mismatch: 8, identity: 0.733

atcgagatcggcgaccagggtcagcgtcga	CRISPR spacer
tgcgagatcggcgacctggctcagccaggt	Protospacer
  ************** ** *****   *

24. spacer 2.4|1702865|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to KF024728 (Mycobacterium phage Muddy, complete genome) position: , mismatch: 8, identity: 0.733

atcgagatcggcgaccagggtcagcgtcga	CRISPR spacer
agccgcatcggcgaccagagtcagcgtacg	Protospacer
* * . ************.********  .

25. spacer 2.4|1702865|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to CP000877 (Herpetosiphon aurantiacus DSM 785 plasmid pHAU02, complete sequence) position: , mismatch: 8, identity: 0.733

atcgagatcggcgaccagggtcagcgtcga	CRISPR spacer
gcagccatcggcgaccacggccagcgtcgt	Protospacer
.. *  *********** **.********

26. spacer 2.4|1702865|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to MN908690 (Microbacterium phage Hubbs, complete genome) position: , mismatch: 8, identity: 0.733

atcgagatcggcgaccagggtcagcgtcga	CRISPR spacer
ggcgagatcggcgaccccggtcagcccccg	Protospacer
. **************  ******* .* .

27. spacer 2.4|1702865|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to MN096374 (Microbacterium phage Roman, complete genome) position: , mismatch: 8, identity: 0.733

atcgagatcggcgaccagggtcagcgtcga	CRISPR spacer
ggcgagatcggcgaccccggtcagcccccg	Protospacer
. **************  ******* .* .

28. spacer 2.4|1702865|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to MK919474 (Microbacterium phage Lupine, complete genome) position: , mismatch: 8, identity: 0.733

atcgagatcggcgaccagggtcagcgtcga	CRISPR spacer
ggcgagatcggcgaccccggtcagcccccg	Protospacer
. **************  ******* .* .

29. spacer 2.6|1702997|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP017148 (Bosea vaviloviae strain Vaf18 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

catgctggggaacctgccacgcgactgcca	CRISPR spacer
taagccggggaacctgccacgcgaagccgg	Protospacer
.* **.******************   * .

30. spacer 2.8|1703129|31|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NC_006552 (Pseudomonas phage F116, complete genome) position: , mismatch: 8, identity: 0.742

cttcatcgactattacgaggcagtcgggcag	CRISPR spacer
cttcatcgactactacgaggcacacaacgaa	Protospacer
************.*********  *..  *.

31. spacer 2.8|1703129|31|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to AY625898 (Pseudomonas aeruginosa phage F116, complete genome) position: , mismatch: 8, identity: 0.742

cttcatcgactattacgaggcagtcgggcag	CRISPR spacer
cttcatcgactactacgaggcacacaacgaa	Protospacer
************.*********  *..  *.

32. spacer 2.8|1703129|31|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to LT603684 (Pseudomonas phage phiC725A genome assembly) position: , mismatch: 8, identity: 0.742

cttcatcgactattacgaggcagtcgggcag	CRISPR spacer
cttcatcgactactacgaggcacacaacgaa	Protospacer
************.*********  *..  *.

33. spacer 2.14|1703526|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to MK376343 (Pseudomonas sp. strain ANT_J16 plasmid pA16J1, complete sequence) position: , mismatch: 8, identity: 0.733

ccgcgcggccatcggatcgagtgcagccag	CRISPR spacer
tatggtggccatcggatcgagtgcagcaga	Protospacer
.   *.********************* ..

34. spacer 2.16|1703658|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP054841 (Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

cctggactactgcaagcgggctggcgtgat	CRISPR spacer
gtagacctgctgcaagcgggccggcgtgag	Protospacer
 . *. **.************.*******

35. spacer 2.17|1703724|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NC_015969 (UNVERIFIED_ORG: Enterobacter soli plasmid pENTAS02, complete sequence) position: , mismatch: 8, identity: 0.733

gtatcgccctcataggtcagggttacagcc	CRISPR spacer
atatcgccgtcataggtcagggcaccggtg	Protospacer
.******* *************.  *.*.

36. spacer 2.22|1704055|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to KT997869 (Uncultured Mediterranean phage uvDeep-CGR2-AD3-C76, complete genome) position: , mismatch: 8, identity: 0.733

gcgcttgaacagcaaaaagagcatgccagg	CRISPR spacer
gcgctcgaacagcaaaaagagggacagtgg	Protospacer
*****.*************** .     **

37. spacer 2.24|1704187|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP013632 (Rhizobium sp. N324 plasmid pRspN324b, complete sequence) position: , mismatch: 8, identity: 0.733

atactcctcttcggagtcgagcatcagcgt	CRISPR spacer
caccacctcttcggcgtcgagcatccgccc	Protospacer
   * ********* ********** ** .

38. spacer 2.2|1702733|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NC_015184 (Agrobacterium sp. H13-3 plasmid pAspH13-3a, complete sequence) position: , mismatch: 9, identity: 0.7

gtcggccacccagaccgttacccggtcggt	CRISPR spacer
gtcggccacccagaccgtgaccaacatacc	Protospacer
****************** *** .  .. .

39. spacer 2.3|1702799|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP054609 (Paenibacillus cellulosilyticus strain KACC 14175 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

tactacggacatggccccgacgccgatcac	CRISPR spacer
cttataggacatagccccgaagccgatcag	Protospacer
. .   ******.******* ********

40. spacer 2.12|1703395|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP045385 (Ruegeria sp. THAF33 plasmid pTHAF33_a, complete sequence) position: , mismatch: 9, identity: 0.7

cctcgctggctacggcagcgactgcacggt	CRISPR spacer
cctcgctggcaacggcagcgaccatgtcca	Protospacer
********** ***********.....

41. spacer 2.18|1703790|31|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP020970 (Xanthomonas phaseoli pv. phaseoli strain CFBP6164 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.71

gagctgcgccgactggacgccagcgaggcaa	CRISPR spacer
gtcctgcgccgactggccggcagcgactgtg	Protospacer
*  ************* ** ******    .

42. spacer 2.18|1703790|31|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP023549 (Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.71

gagctgcgccgactggacgccagcgaggcaa	CRISPR spacer
atcgtgcgccggctggacgccatcgagaccc	Protospacer
.   *******.********** ****.*

43. spacer 2.19|1703857|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to NC_020062 (Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence) position: , mismatch: 9, identity: 0.7

cgggtgacaccttgtccagcgcctcatcag	CRISPR spacer
attcatacaccttggccagcgcctcatcgt	Protospacer
      ******** *************.

44. spacer 2.23|1704121|30|NZ_CP010855|CRT,PILER-CR,CRISPRCasFinder matches to MK433266 (Streptomyces phage Shawty, complete genome) position: , mismatch: 9, identity: 0.7

gcacttgccgaggctgaggcgcaactttcc	CRISPR spacer
gcacttgccgacgctgaggcgaaggcgctg	Protospacer
*********** ********* *. . ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1653896 : 1694165

Pandoravirus(13.33%)

protease,integrase,terminase,tail,portal

attL 1666233:1666251|attR 1682855:1682873

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048531492.1\|1653896_1654424_-\|tail	phage tail protein	E3T4R8	Cafeteria_roenbergensis_virus	2.0e-18	38.8
WP_048531494.1\|1654677_1655988_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_048531496.1\|1656073_1656997_-	site-specific tyrosine recombinase XerD	A0A1P8DJJ6	Virus_Rctr41k	1.4e-19	28.8
WP_048531498.1\|1657002_1658559_-	hypothetical protein	NA	NA	NA	NA
WP_170850513.1\|1658548_1658698_-	hypothetical protein	NA	NA	NA	NA
WP_048531500.1\|1658841_1659387_+	shikimate kinase	NA	NA	NA	NA
WP_048531502.1\|1659386_1660499_+	3-dehydroquinate synthase	A9YVT7	Ostreococcus_tauri_virus	3.0e-19	30.2
WP_048531504.1\|1660585_1661227_-	DUF1638 domain-containing protein	NA	NA	NA	NA
WP_048531506.1\|1661223_1661925_-	cobalamin-dependent protein	NA	NA	NA	NA
WP_048531507.1\|1662103_1663189_+	PA0069 family radical SAM protein	NA	NA	NA	NA
WP_048531509.1\|1663291_1664308_-	betaine--homocysteine S-methyltransferase	NA	NA	NA	NA
WP_048531510.1\|1664517_1664832_-	DUF1476 domain-containing protein	NA	NA	NA	NA
WP_048531512.1\|1664993_1665755_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	1.1e-46	42.2
WP_048531514.1\|1665847_1666078_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_048531516.1\|1666123_1666798_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
1666233:1666251	attL	NA	NA	NA	NA
WP_048531518.1\|1666850_1668635_+	sensor histidine kinase	NA	NA	NA	NA
WP_048531520.1\|1668661_1669999_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_048531522.1\|1670053_1671175_+	aminodeoxychorismate synthase component I	S4VT78	Pandoravirus	8.1e-49	45.3
WP_082154581.1\|1671183_1671786_+	aminotransferase class IV	A0A0B5J984	Pandoravirus	1.2e-09	30.7
WP_048531525.1\|1671861_1672938_-	ornithine cyclodeaminase	A0A1V0SL93	Klosneuvirus	1.7e-83	46.7
WP_048531526.1\|1672937_1673864_-	arginase	A0A1V0SJM8	Klosneuvirus	4.3e-24	34.1
WP_048531527.1\|1673982_1674408_+	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_048531529.1\|1674425_1674893_-	disulfide bond formation protein B	NA	NA	NA	NA
WP_048531531.1\|1674892_1675471_-	DedA family protein	NA	NA	NA	NA
WP_048531533.1\|1675751_1676795_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_048531535.1\|1676791_1677004_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_048531537.1\|1677006_1677234_-	hypothetical protein	NA	NA	NA	NA
WP_048531539.1\|1677230_1677818_-	hypothetical protein	NA	NA	NA	NA
WP_148562841.1\|1677814_1678057_-	hypothetical protein	NA	NA	NA	NA
WP_148562842.1\|1678268_1678625_-	hypothetical protein	NA	NA	NA	NA
WP_148562843.1\|1679061_1679397_+	hypothetical protein	NA	NA	NA	NA
WP_158499022.1\|1679393_1679570_+	hypothetical protein	NA	NA	NA	NA
WP_158499023.1\|1679718_1679859_+	hypothetical protein	NA	NA	NA	NA
WP_048531545.1\|1679963_1680698_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_048531547.1\|1680690_1681281_+	hypothetical protein	NA	NA	NA	NA
WP_048531549.1\|1681277_1681931_+	hypothetical protein	G8DGC1	Emiliania_huxleyi_virus	5.8e-39	46.0
WP_048531551.1\|1682058_1682673_+	hypothetical protein	A0A0K1LLF3	Rhodobacter_phage	1.6e-27	37.6
WP_048531553.1\|1682799_1683453_+	DUF1441 family protein	NA	NA	NA	NA
1682855:1682873	attR	NA	NA	NA	NA
WP_048531555.1\|1683457_1685599_+\|terminase	phage terminase large subunit family protein	A5LH27	Enterobacteria_phage	2.3e-92	35.4
WP_048531557.1\|1685609_1685813_+	hypothetical protein	NA	NA	NA	NA
WP_048531560.1\|1685818_1687285_+\|portal	phage portal protein	Q9JMM5	Wolbachia_phage	1.5e-50	33.6
WP_048531561.1\|1687271_1689395_+\|protease	ATP-dependent Clp protease proteolytic subunit	C7BGG9	Burkholderia_phage	1.9e-14	34.6
WP_048531563.1\|1689500_1689827_+	DUF2190 family protein	NA	NA	NA	NA
WP_048531565.1\|1689826_1690159_+	hypothetical protein	NA	NA	NA	NA
WP_148562844.1\|1690158_1690356_+	hypothetical protein	NA	NA	NA	NA
WP_148562845.1\|1690327_1690747_+	hypothetical protein	NA	NA	NA	NA
WP_048531568.1\|1690779_1691172_+	hypothetical protein	A0A291AUU2	Sinorhizobium_phage	8.5e-14	36.9
WP_048531570.1\|1691168_1691663_+	hypothetical protein	NA	NA	NA	NA
WP_048531572.1\|1691804_1694165_+\|tail	phage tail tape measure protein	A0A0K1LLB8	Rhodobacter_phage	2.6e-57	49.4

DBSCAN-SWA_2

1710060 : 1761145

Corynebacterium_phage(42.86%)

integrase,protease,transposase,head

attL 1754437:1754482|attR 1766980:1767025

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048528913.1\|1710060_1711266_+\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	2.3e-97	49.0
WP_148562848.1\|1711837_1712494_+	hypothetical protein	NA	NA	NA	NA
WP_148562849.1\|1712495_1714802_+	UvrD-helicase domain-containing protein	NA	NA	NA	NA
WP_148562850.1\|1714990_1715227_-	hypothetical protein	NA	NA	NA	NA
WP_048531601.1\|1715321_1715645_-	hypothetical protein	NA	NA	NA	NA
WP_048531605.1\|1716653_1717136_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_048531607.1\|1717281_1718232_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_048531609.1\|1718315_1719935_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_148562851.1\|1719947_1720139_+	DUF2783 domain-containing protein	NA	NA	NA	NA
WP_048531613.1\|1720164_1720542_-	DUF1428 domain-containing protein	NA	NA	NA	NA
WP_048531615.1\|1720566_1721049_-	VOC family protein	NA	NA	NA	NA
WP_048531617.1\|1721045_1721477_-	VOC family protein	NA	NA	NA	NA
WP_048531618.1\|1722030_1722609_+	L,D-transpeptidase	NA	NA	NA	NA
WP_048531620.1\|1722693_1723710_-	4-hydroxythreonine-4-phosphate dehydrogenase PdxA	NA	NA	NA	NA
WP_048531621.1\|1723706_1724987_-	TRAP transporter large permease	NA	NA	NA	NA
WP_048531622.1\|1724983_1725547_-	TRAP transporter small permease	NA	NA	NA	NA
WP_048531623.1\|1725613_1726597_-	TRAP transporter substrate-binding protein	NA	NA	NA	NA
WP_048531625.1\|1726752_1727406_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_048531628.1\|1727466_1728411_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_074835802.1\|1728401_1728887_-	RidA family protein	NA	NA	NA	NA
WP_148562919.1\|1729196_1730612_+	amidase	NA	NA	NA	NA
WP_048531632.1\|1730598_1731585_+	TRAP transporter substrate-binding protein	NA	NA	NA	NA
WP_048531633.1\|1731605_1732115_+	TRAP transporter small permease	NA	NA	NA	NA
WP_048531635.1\|1732124_1733399_+	TRAP transporter large permease	NA	NA	NA	NA
WP_048531637.1\|1733617_1734931_-	TRAP transporter large permease subunit	NA	NA	NA	NA
WP_048531639.1\|1734935_1735472_-	TRAP transporter small permease	NA	NA	NA	NA
WP_082154455.1\|1735543_1736230_-	TRAP transporter substrate-binding protein DctP	NA	NA	NA	NA
WP_048528918.1\|1736290_1737856_+\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_048528916.1\|1737788_1738517_+	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.8e-33	33.2
WP_082154456.1\|1738565_1738910_-	heme-binding protein	NA	NA	NA	NA
WP_048531641.1\|1738999_1739608_-	response regulator transcription factor	NA	NA	NA	NA
WP_048533766.1\|1739604_1741074_-	two-component sensor histidine kinase	NA	NA	NA	NA
WP_082154583.1\|1741502_1741850_-	RidA family protein	NA	NA	NA	NA
WP_053083350.1\|1741852_1742620_-	ABC transporter permease	NA	NA	NA	NA
WP_048531645.1\|1742622_1743312_-	ABC transporter permease	NA	NA	NA	NA
WP_048531647.1\|1743378_1744170_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_048531648.1\|1744193_1744964_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	1.2e-32	39.8
WP_048531651.1\|1744960_1746349_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_048531653.1\|1746341_1746659_-	(2Fe-2S)-binding protein	NA	NA	NA	NA
WP_048531655.1\|1746624_1747749_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_158499024.1\|1747887_1748754_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_048531658.1\|1749547_1749796_+	hypothetical protein	NA	NA	NA	NA
WP_048528913.1\|1750129_1751335_-\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	2.3e-97	49.0
WP_148562852.1\|1751451_1751934_-	hypothetical protein	NA	NA	NA	NA
WP_148562853.1\|1752038_1754306_-	hypothetical protein	NA	NA	NA	NA
1754437:1754482	attL	NA	NA	NA	NA
WP_048531662.1\|1754522_1755647_-\|integrase	tyrosine-type recombinase/integrase	A0A076G7B8	Sinorhizobium_phage	1.5e-106	50.7
WP_048528913.1\|1756005_1757211_+\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	2.3e-97	49.0
WP_082154458.1\|1757129_1757396_-	Arc family DNA-binding protein	NA	NA	NA	NA
WP_048531664.1\|1757482_1757725_+	Arc family DNA-binding protein	NA	NA	NA	NA
WP_148562854.1\|1757721_1758348_+	hypothetical protein	NA	NA	NA	NA
WP_148562855.1\|1758348_1758609_-	hypothetical protein	NA	NA	NA	NA
WP_048531668.1\|1758601_1758991_-	hypothetical protein	NA	NA	NA	NA
WP_148562856.1\|1758987_1760001_-	hypothetical protein	NA	NA	NA	NA
WP_048531671.1\|1759997_1760561_-	hypothetical protein	NA	NA	NA	NA
WP_158499025.1\|1760557_1761145_-\|head,protease	HK97 family phage prohead protease	A0A1B2APW1	Phage_Wrath	4.0e-07	30.7
1766980:1767025	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1874991 : 1885921

Streptococcus_phage(25.0%)

transposase,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048531815.1\|1874991_1875477_-\|terminase	phage terminase small subunit P27 family	Q6DMU4	Streptococcus_phage	2.8e-22	40.3
WP_048531816.1\|1876187_1876931_-	hypothetical protein	NA	NA	NA	NA
WP_048531818.1\|1876940_1877981_-	hypothetical protein	NA	NA	NA	NA
WP_048531819.1\|1878282_1878984_-	recombinase family protein	A0A0F7L6S1	uncultured_marine_virus	3.4e-37	45.7
WP_053083352.1\|1879061_1879568_-\|terminase	phage terminase small subunit P27 family	Q6DMU4	Streptococcus_phage	1.1e-21	42.9
WP_048531820.1\|1879564_1880011_-	hypothetical protein	A0A0R6PHW5	Moraxella_phage	1.9e-25	58.8
WP_048531821.1\|1880010_1880229_-	hypothetical protein	K4I1E3	Acidithiobacillus_phage	1.4e-10	53.5
WP_048531823.1\|1880225_1881503_-	site-specific DNA-methyltransferase	A0A0A8ILE7	Aurantimonas_phage	3.6e-130	56.9
WP_048531824.1\|1882023_1883589_+\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_048528916.1\|1883521_1884250_+	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.8e-33	33.2
WP_048531825.1\|1884412_1885921_+	SAM-dependent DNA methyltransferase	A0A220A2U5	Liberibacter_phage	1.4e-125	50.7

DBSCAN-SWA_4

2193837 : 2207712

Paracoccus_phage(30.0%)

protease,head,tail,capsid,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048532093.1\|2193837_2197833_-	glycoside hydrolase TIM-barrel-like domain-containing protein	A0A0B5A7K5	Paracoccus_phage	1.6e-232	39.9
WP_048532094.1\|2197832_2198276_-	peptidase	A0A1V0DYB6	Dinoroseobacter_phage	6.9e-28	49.3
WP_048532095.1\|2198272_2199160_-	DUF2163 domain-containing protein	A0A0K0PVK1	Roseobacter_phage	7.8e-55	38.1
WP_048532096.1\|2199156_2199789_-	DUF2460 domain-containing protein	A0A0B5A2K3	Paracoccus_phage	1.8e-53	46.9
WP_048532097.1\|2199805_2200456_-\|tail	phage tail tape measure protein	D6PFD6	uncultured_phage	7.8e-12	31.8
WP_074836801.1\|2200455_2200626_-\|tail	phage tail assembly chaperone	NA	NA	NA	NA
WP_048532099.1\|2200649_2200976_-	gene transfer agent family protein	NA	NA	NA	NA
WP_048532100.1\|2200979_2201393_-\|tail	phage major tail protein, TP901-1 family	A0A1J0GVL1	Pseudoalteromonas_phage	5.9e-05	31.9
WP_048532101.1\|2201416_2201827_-	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_048532102.1\|2201823_2202162_-\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
WP_048533815.1\|2202158_2202764_-	gene transfer agent protein	NA	NA	NA	NA
WP_048532103.1\|2202927_2204106_-\|capsid	phage major capsid protein	B0VK33	Azospirillum_phage	1.9e-64	41.7
WP_193388040.1\|2204128_2204683_-\|head,protease	HK97 family phage prohead protease	A0A0U2BX10	Paracoccus_phage	6.8e-33	46.3
WP_048532105.1\|2204756_2204978_-	hypothetical protein	NA	NA	NA	NA
WP_048532106.1\|2204970_2206149_-\|portal	phage portal protein	W8ECU7	Geobacillus_phage	4.1e-59	36.9
WP_193388041.1\|2206344_2207712_-	DNA-packaging protein	A0A1V0DY66	Dinoroseobacter_phage	4.7e-75	39.0

DBSCAN-SWA_5

2500280 : 2551545

Thiobacimonas_phage(34.21%)

protease,transposase,head,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048532364.1\|2500280_2501546_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	5.6e-131	56.3
WP_048532365.1\|2501671_2502301_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	7.9e-62	60.8
WP_048532366.1\|2502417_2504397_-	two-component sensor histidine kinase	NA	NA	NA	NA
WP_048532367.1\|2504513_2505101_-	riboflavin synthase	A0A2I2L4R9	Orpheovirus	4.4e-22	35.6
WP_048532368.1\|2505199_2506492_+	capsular biosynthesis protein	NA	NA	NA	NA
WP_148562923.1\|2506628_2507759_+	polysaccharide biosynthesis/export family protein	NA	NA	NA	NA
WP_048532370.1\|2507763_2509797_+	capsular polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_048532371.1\|2509805_2510876_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	1.7e-40	32.4
WP_048532372.1\|2510917_2511385_-	transcriptional repressor NrdR	NA	NA	NA	NA
WP_048532373.1\|2511638_2513393_-	DNA methylase	A0A2L1IZ21	Streptomyces_phage	8.6e-122	44.8
WP_148562866.1\|2513590_2516701_-	hypothetical protein	A0A076GD25	Sinorhizobium_phage	3.5e-17	54.6
WP_048532374.1\|2516720_2520044_-	hypothetical protein	A0A1B0T6D1	Thiobacimonas_phage	2.9e-251	45.8
WP_048532375.1\|2520040_2520451_-	C40 family peptidase	M4SRS7	Rhodobacter_phage	1.1e-30	50.4
WP_048532376.1\|2520447_2520972_-	hypothetical protein	A0A1B0T6D7	Thiobacimonas_phage	8.7e-46	56.3
WP_048532377.1\|2520968_2521391_-	hypothetical protein	A0A1B0T6E0	Thiobacimonas_phage	1.4e-25	55.3
WP_048532378.1\|2521387_2524183_-\|tail	phage tail length tape measure family protein	I3UM47	Rhodobacter_phage	3.2e-14	38.2
WP_082154504.1\|2524184_2524469_-	DUF1799 domain-containing protein	NA	NA	NA	NA
WP_048532379.1\|2524534_2524855_-	hypothetical protein	NA	NA	NA	NA
WP_048532380.1\|2524870_2525800_-	hypothetical protein	A0A1B0T6E1	Thiobacimonas_phage	5.4e-91	53.9
WP_158499038.1\|2525800_2525950_-	hypothetical protein	NA	NA	NA	NA
WP_048532381.1\|2525946_2526375_-	hypothetical protein	A0A1B0T6E9	Thiobacimonas_phage	1.2e-29	44.8
WP_048532382.1\|2526374_2526803_-	DUF1320 domain-containing protein	M4SPQ8	Rhodobacter_phage	1.5e-43	59.9
WP_048532383.1\|2527077_2527434_-	hypothetical protein	NA	NA	NA	NA
WP_048532384.1\|2527446_2528340_-\|head	Mu-like prophage major head subunit gpT family protein	M4SRT6	Rhodobacter_phage	8.8e-131	74.4
WP_048532385.1\|2528352_2528787_-	hypothetical protein	A0A1B0T6E4	Thiobacimonas_phage	6.1e-45	66.7
WP_048532386.1\|2528786_2529833_-	hypothetical protein	A0A1B0T6E7	Thiobacimonas_phage	4.2e-92	52.8
WP_048532387.1\|2529937_2530435_-	phage virion morphogenesis protein	M4ST99	Rhodobacter_phage	9.8e-31	45.0
WP_048532388.1\|2530437_2530617_-	hypothetical protein	NA	NA	NA	NA
WP_053083364.1\|2530613_2531552_-	hypothetical protein	A0A1B0T6H8	Thiobacimonas_phage	1.1e-96	68.4
WP_048532389.1\|2531544_2533191_-	DUF935 domain-containing protein	A0A1B0T6F2	Thiobacimonas_phage	3.6e-199	63.9
WP_148562924.1\|2533307_2534963_-	hypothetical protein	A0A219VH72	Ochrobactrum_phage	3.1e-182	63.4
WP_048532391.1\|2534983_2535169_-	hypothetical protein	NA	NA	NA	NA
WP_048532392.1\|2535165_2535435_-	hypothetical protein	NA	NA	NA	NA
WP_053083365.1\|2535431_2535785_-	hypothetical protein	M4T564	Rhodobacter_phage	8.2e-24	61.4
WP_048532393.1\|2535781_2536363_-	DUF3486 family protein	A0A1B0T6K5	Pelagibaca_phage	7.6e-43	52.3
WP_048532394.1\|2536367_2536667_-	hypothetical protein	A0A1B1P718	Rhodovulum_phage	1.6e-28	65.7
WP_048532395.1\|2536667_2537063_-	DUF2730 family protein	A0A1B0T6F6	Thiobacimonas_phage	2.4e-16	43.0
WP_048532396.1\|2537035_2537563_-	hypothetical protein	M4SRV1	Rhodobacter_phage	1.1e-40	50.3
WP_048532397.1\|2537562_2538474_-	peptidoglycan-binding protein	G8GWD3	Rhodobacter_phage	1.6e-71	52.4
WP_048532398.1\|2538593_2538986_-	hypothetical protein	M4SNV1	Rhodobacter_phage	2.9e-22	46.3
WP_082154595.1\|2538982_2539588_-	S-adenosylmethionine-binding protein	M4SPS7	Rhodobacter_phage	2.1e-80	72.2
WP_082154505.1\|2539590_2539845_-	hypothetical protein	A0A1B0T6G9	Thiobacimonas_phage	2.9e-07	38.6
WP_048533877.1\|2539841_2540300_-	regulatory protein GemA	A0A1B0T6H1	Thiobacimonas_phage	2.3e-42	60.5
WP_158499039.1\|2540412_2540586_-	hypothetical protein	NA	NA	NA	NA
WP_048532400.1\|2540591_2540912_-	hypothetical protein	NA	NA	NA	NA
WP_048532401.1\|2540913_2541555_-	DUF3164 family protein	M4STB6	Rhodobacter_phage	3.1e-69	60.2
WP_148562867.1\|2541551_2541941_-	hypothetical protein	W6MW33	Pseudomonas_phage	1.3e-09	65.2
WP_048532403.1\|2541933_2542263_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_048532404.1\|2542252_2542630_-	hypothetical protein	A0A1B0T6M5	Pelagibaca_phage	1.1e-29	55.4
WP_048532405.1\|2542626_2543196_-	hypothetical protein	NA	NA	NA	NA
WP_082154506.1\|2543192_2543936_-	AAA family ATPase	M4SPU5	Rhodobacter_phage	9.1e-49	45.6
WP_048532407.1\|2544004_2546158_-\|transposase	Mu transposase C-terminal domain-containing protein	A0A1B1P6Z4	Rhodovulum_phage	2.9e-180	47.8
WP_048532408.1\|2546150_2547011_-	ParB N-terminal domain-containing protein	A0A1B0T6H9	Thiobacimonas_phage	1.6e-41	38.5
WP_048532409.1\|2547010_2547484_-	hypothetical protein	NA	NA	NA	NA
WP_048532410.1\|2547953_2548226_-	hypothetical protein	NA	NA	NA	NA
WP_148562868.1\|2548313_2549072_+	hypothetical protein	NA	NA	NA	NA
WP_148562869.1\|2549108_2549660_+	hypothetical protein	NA	NA	NA	NA
WP_048528913.1\|2550339_2551545_+\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	2.3e-97	49.0

DBSCAN-SWA_6

2555778 : 2563778

Pelagibaca_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048528916.1\|2555778_2556507_+	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.8e-33	33.2
WP_048532415.1\|2556613_2556937_-	hypothetical protein	NA	NA	NA	NA
WP_048532416.1\|2556929_2557259_-	hypothetical protein	NA	NA	NA	NA
WP_048532417.1\|2557248_2557626_-	hypothetical protein	A0A1B0T6M5	Pelagibaca_phage	1.4e-29	55.7
WP_048532418.1\|2557622_2558192_-	hypothetical protein	NA	NA	NA	NA
WP_082154508.1\|2558188_2558932_-	AAA family ATPase	M4SPU5	Rhodobacter_phage	5.9e-48	45.6
WP_048532420.1\|2558999_2561153_-\|transposase	Mu transposase C-terminal domain-containing protein	A0A1B1P6Z4	Rhodovulum_phage	1.0e-185	48.7
WP_048532421.1\|2561145_2561982_-	ParB N-terminal domain-containing protein	A0A1B1P710	Rhodovulum_phage	5.3e-45	44.0
WP_048532422.1\|2561981_2562236_-	hypothetical protein	NA	NA	NA	NA
WP_048532423.1\|2562232_2562703_-	hypothetical protein	NA	NA	NA	NA
WP_148562871.1\|2562702_2562951_-	hypothetical protein	NA	NA	NA	NA
WP_048532425.1\|2563058_2563778_+	hypothetical protein	A0A1B0T6N0	Pelagibaca_phage	6.6e-12	31.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP010865

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP010861

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP010855

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection