CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP011804	Clostridium carboxidivorans P7 plasmid unnamed, complete sequence	0 crisprs	NA	0	0	1	0
NZ_CP011803	Clostridium carboxidivorans P7 chromosome, complete genome	2 crisprs	csa3,DEDDh,WYL,DinG,cas3,cas7,cas6,cas5,PD-DExK,RT,cas14j	0	0	4	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

7829 : 17440

Bacillus_phage(66.67%)

integrase

attL 11816:11828|attR 17926:17938

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007063229.1\|7829_9101_-	hypothetical protein	A0A1B1P892	Bacillus_phage	3.8e-18	24.8
WP_007063230.1\|9459_10203_-	ORF6C domain-containing protein	A0A288WG93	Bacillus_phage	1.5e-51	45.7
WP_007063231.1\|10284_11172_-\|integrase	tyrosine-type recombinase/integrase	A0A1B1P7C7	Bacillus_phage	2.2e-17	27.2
WP_007063232.1\|11215_11425_-	hypothetical protein	NA	NA	NA	NA
WP_007063233.1\|11609_11846_-	hypothetical protein	NA	NA	NA	NA
11816:11828	attL	NA	NA	NA	NA
WP_007063234.1\|11961_14490_-	hypothetical protein	A8ATH6	Listeria_phage	1.1e-16	25.6
WP_007063235.1\|14529_14700_-	hypothetical protein	NA	NA	NA	NA
WP_007063236.1\|14720_15440_-	hypothetical protein	NA	NA	NA	NA
WP_007063237.1\|15824_16535_+	helix-turn-helix transcriptional regulator	A0A0A7RUJ5	Clostridium_phage	4.8e-07	43.9
WP_007063238.1\|16603_17440_-\|integrase	tyrosine-type recombinase/integrase	A0A1B1P7C7	Bacillus_phage	2.4e-21	25.2
17926:17938	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP011803

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP011803_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011803_1

367455-367541

Orphan

Consensus_repeat	Method
AATTTAAATACAAATGGTATAACTACAAAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP011803_1

>merge|NZ_CP011803|1|367455-367541|CRISPRCasFinder
AATTTAAATACAAATGGTATAACTACAAATATAATGATAGGGCGTGGAATAGTTCAGAATTTAAATATAAATGGTATAACTACAAAT

>NZ_CP011803|1|1|367455-367541|CRISPRCasFinder
AATTTAAATACAAATGGTATAACTACAAAT	ATAATGATAGGGCGTGGAATAGTTCAG
AATTTAAATATAAATGGTATAACTACAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011803.1\|WP_007064462.1\|372078_373380_+\|glycosyltransferase-family-39-protein	unknown	unknown	gnl\|CDD\|224720
NZ_CP011803.1\|WP_007064467.1\|359091_359889_+\|ribose-phosphate-pyrophosphokinase	unknown	unknown	gnl\|CDD\|223538
NZ_CP011803.1\|WP_035774366.1\|358145_358694_+\|NADAR-family-protein	unknown	unknown	gnl\|CDD\|378035
NZ_CP011803.1\|WP_007059796.1\|361538_367079_+\|DNRLRE-domain-containing-protein	unknown	unknown	unknown
NZ_CP011803.1\|WP_007059806.1\|352043_353414_+\|D-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|235096
NZ_CP011803.1\|WP_007059801.1\|357229_358129_+\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|223979
NZ_CP011803.1\|WP_007059789.1\|371322_371778_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341362
NZ_CP011803.1\|WP_007059792.1\|370021_370198_+\|aspartyl-phosphate-phosphatase-Spo0E-family-protein	unknown	unknown	gnl\|CDD\|378175
NZ_CP011803.1\|WP_007064464.1\|370445_371240_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|369792
NZ_CP011803.1\|WP_007059807.1\|351070_351970_+\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NZ_CP011803.1\|WP_007059797.1\|359903_361373_+\|nicotinate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|236407
NZ_CP011803.1\|WP_007059793.1\|368949_369813_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP011803.1\|WP_007059785.1\|376192_376948_+\|proline-reductase-cluster-protein-PrdD	unknown	unknown	gnl\|CDD\|275275
NZ_CP011803.1\|WP_007059783.1\|378188_379514_+\|amidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|378910
NZ_CP011803.1\|WP_007059805.1\|353462_353750_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011803.1\|WP_007059794.1\|367985_368741_-\|TSUP-family-transporter	unknown	unknown	gnl\|CDD\|182593
NZ_CP011803.1\|WP_007064470.1\|355127_357011_+\|PTS-fructose-transporter-subunit-IIABC	unknown	unknown	gnl\|CDD\|236740
NZ_CP011803.1\|WP_007064461.1\|377002_377968_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769
NZ_CP011803.1\|WP_007059786.1\|373794_375951_-\|formate-dehydrogenase-subunit-alpha	unknown	unknown	gnl\|CDD\|130652
NZ_CP011803.1\|WP_007059804.1\|354080_354992_+\|1-phosphofructokinase	unknown	unknown	gnl\|CDD\|274464

Protein	Function_ID	Function_description	E-value
NZ_CP011803.1\|WP_007064462.1\|372078_373380_+\|glycosyltransferase-family-39-protein	gnl\|CDD\|224720	COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane].	1.04207e-05
NZ_CP011803.1\|WP_007064467.1\|359091_359889_+\|ribose-phosphate-pyrophosphokinase	gnl\|CDD\|223538	COG0462, PrsA, Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism / Amino acid transport and metabolism].	4.16482e-31
NZ_CP011803.1\|WP_035774366.1\|358145_358694_+\|NADAR-family-protein	gnl\|CDD\|378035	pfam08719, DUF1768, Domain of unknown function (DUF1768). This is a domain of unknown function. It is alpha helical in structure. The GO annotation for this protein suggests it is involved in nematode larval development and has a positive regulation on growth rate.	4.25908e-79
NZ_CP011803.1\|WP_007059806.1\|352043_353414_+\|D-serine-ammonia-lyase	gnl\|CDD\|235096	PRK02991, PRK02991, D-serine dehydratase; Provisional.	0
NZ_CP011803.1\|WP_007059789.1\|371322_371778_-\|CBS-domain-containing-protein	gnl\|CDD\|341362	cd04586, CBS_pair_BON_assoc, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the BON (bacterial OsmY and nodulation domain) domain. This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the BON (bacterial OsmY and nodulation domain) domain. BON is a putative phospholipid-binding domain found in a family of osmotic shock protection proteins. It is also found in some secretins and a group of potential haemolysins. Its likely function is attachment to phospholipid membranes. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	1.5296e-30
NZ_CP011803.1\|WP_007059794.1\|367985_368741_-\|TSUP-family-transporter	gnl\|CDD\|182593	PRK10621, PRK10621, hypothetical protein; Provisional.	9.96291e-54
NZ_CP011803.1\|WP_007064464.1\|370445_371240_+\|HAD-family-hydrolase	gnl\|CDD\|369792	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase. This family contains haloacid dehalogenase-like hydrolase enzymes.	6.08927e-61
NZ_CP011803.1\|WP_007059807.1\|351070_351970_+\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	4.2609e-98
NZ_CP011803.1\|WP_007059797.1\|359903_361373_+\|nicotinate-phosphoribosyltransferase	gnl\|CDD\|236407	PRK09198, PRK09198, putative nicotinate phosphoribosyltransferase; Provisional.	0
NZ_CP011803.1\|WP_007059793.1\|368949_369813_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	5.77195e-58
NZ_CP011803.1\|WP_007059785.1\|376192_376948_+\|proline-reductase-cluster-protein-PrdD	gnl\|CDD\|275275	TIGR04482, D_pro_red_PrdD, proline reductase cluster protein PrdD. Members of this family are PrdD, encoded in the proline reductase gene cluster. Members are closely homologous to PrdA, which cleaves during maturation to create two subunits of the subunits of the proline reductase complex, one of which has a Cys-derived pyruvoyl active site.	8.89767e-145
NZ_CP011803.1\|WP_007059783.1\|378188_379514_+\|amidase-domain-containing-protein	gnl\|CDD\|378910	pfam12671, Amidase_6, Putative amidase domain.	5.20865e-48
NZ_CP011803.1\|WP_007059801.1\|357229_358129_+\|NUDIX-hydrolase	gnl\|CDD\|223979	COG1051, COG1051, ADP-ribose pyrophosphatase [Nucleotide transport and metabolism].	2.62427e-26
NZ_CP011803.1\|WP_007059792.1\|370021_370198_+\|aspartyl-phosphate-phosphatase-Spo0E-family-protein	gnl\|CDD\|378175	pfam09388, SpoOE-like, Spo0E like sporulation regulatory protein. Spore formation is an extreme response to starvation and can also be a component of disease transmission. Sporulation is controlled by an expanded two-component system where starvation signals result in sensor kinase activation and phosphorylation of the master sporulation response regulator Spo0A. Phosphatases such as Spo0E dephosphorylate Spo0A thereby inhibiting sporulation. This is a family of Spo0E-like phosphatases. The structure of a Bacillus anthracis member of this family has revealed an anti-parallel alpha-helical structure.	8.04201e-05
NZ_CP011803.1\|WP_007064470.1\|355127_357011_+\|PTS-fructose-transporter-subunit-IIABC	gnl\|CDD\|236740	PRK10712, PRK10712, PTS system fructose-specific transporter subunits IIBC; Provisional.	2.76099e-165
NZ_CP011803.1\|WP_007064461.1\|377002_377968_+\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	1.4309e-16
NZ_CP011803.1\|WP_007059786.1\|373794_375951_-\|formate-dehydrogenase-subunit-alpha	gnl\|CDD\|130652	TIGR01591, Formate_dehydrogenase_subunit_alpha, formate dehydrogenase, alpha subunit, archaeal-type. This model describes a subset of formate dehydrogenase alpha chains found mainly archaea but also in alpha and gamma proteobacteria and a small number of gram positive bacteria. The alpha chain contains domains for molybdopterin dinucleotide binding and molybdopterin oxidoreductase (pfam01568 and pfam00384, respectively). The holo-enzyme also contains beta and gamma subunits. The enzyme catalyzes the oxidation of formate (produced from pyruvate during anaerobic growth) to carbon dioxide with the concomitant release of two electrons and two protons. The enzyme's purpose is to allow growth on formate in some circumstances and, in the case of FdhH in gamma proteobacteria, to pass electrons to hydrogenase (by which process acid is neutralized). This model is well-defined, with only a single fragmentary sequence falling between trusted and noise. The alpha subunit of a version of nitrate reductase is closely related.	0
NZ_CP011803.1\|WP_007059804.1\|354080_354992_+\|1-phosphofructokinase	gnl\|CDD\|274464	TIGR03168, 1-PFK, hexose kinase, 1-phosphofructokinase family. This family consists largely of 1-phosphofructokinases, but also includes tagatose-6-kinases and 6-phosphofructokinases.	1.08024e-135

>NZ_CP011803.1|WP_007059796.1|361538_367079_+|DNRLRE-domain-containing-protein
MLEILFPIEDTCISKYNAKVNFGKSDSLLIGSSSSGNDYYKTLLKFDISSIFSKVSISRVLLRLYVYKKDKTGTQEVSAYKLIQNFNEMEVNWNNQPSHEELGSSSIISDGNLNGYFDIDVTSIVNQWLNDKNEVVHGIEVIASQSASSFIWFRSREYTEEYMWPRLIVEYDDSKLVTDSKQDGDVLIESSNLYQLGNNFSAAYKVKKVGTKETLAVLEISDDGFVWFSEKAVEVVNGECKVIATSSSRKYDRISLVIIKEPELFLPTGSPVMAQSNIINENSAALNYTSNDVNIPVDESGQIMINKTGTANISVNTRAVMYSPNISFNVVGQVKDDEELSNALDDASITNINIPAGDFTIFNHNIDVSRNINISGMVDKQGKPITNLILSDMYMYILTLENIKVELKNLNIIGLTPNAEGINFEGQFLLNCSINLKNVHMMNFNTALNFGNLSNIDISECEFTNNNEALVFDDVINCRVTKTKFKDNSEASVTIENYCSSMDISAEFENSPNNDFIGISIICSYSSPENINITGSSFTGFDLHKRVVYDNVPDLPEYYVIYGVSTENELRDVLTNWTEIGTVNILQSVLDISTTIEIKRPVILSGISREIKISAASNISNLSFAPYSAVIAADSSNVTIQNLTVDGNNFAQNGIYVHGDSCSIYNNIIRNIVRPEGKAACGDGIIAYKEGTTSLPSSINTLNAASNTIMNTARHGIFVEAFNTETKQLFVSTNINVTNNVVDNVWNNPLTPIETQESNGIFSAAVELQGLEKSTTEFKDNLISNVKNNLKRSYIYFSDTNETQIDGVLKSHNANLSSIKIATYPIALNKALITDTNPNGAVLEVGAQTTTGISMTQEEPNAAAALEVVRNGETTVIDKILWDSYDFNINDVISVKCTSQDKVVTNVYKITIVQKTLQPITVSDEQQLRAALLNDSIGHITLLNDITLTSALSINKYIILDSEGNNKFTLTTPNTGNDITFGNGADENVLRSLIIDGELVIDIGEHGSMTIEKVDVSGETKILSGSTNSINLNGVKTDIVQISCNARVAVKPCSASAAQPSIPSDIVRINMNAQEKQAAPPPTLQVANSKVKEVNVRTPRAVVAVNPEAKVERISVEAPKANIQVAAKEKVKTVQVNAQDTTLTLSDEASVETLNLNANNLNISGKNIDNMNIGSGVTDISTIHVEGYEQTNTDTAKAGNSSAVVFALTQNNIKNIILDGVFEGIAISGKSITNISGAVDDREVSVDDIKVLKYSLLVYSIAKINLLPGEYVYDEALEINRPIILQGTSNASLKSKIEKSGTAINILSNNAAVTELQIDNWDIGVKCNENSYSIDIAGCEFTNNNQAIVLHDVRNARIIENKLKYNIQACVVIIGECSNIIINSQFEHSLVNGTKGISIIGENNSIPRRINITGSEFIDFAPNKRIVYTDISDLPDNHVIYDVSTEDSLRTILREWPEVGIINILSDIENISNPIEILRPVILGHNPLVELVQENKQITAGSDISKISFADYSAVIGIKSNDVVIVNLTVDGKGYAENGIYVWGDNCGIYGNTIKNIVRPNSKAACGSGITVYKSGDTDSPVSINRLNIMDNNISNTARQGIFVGTYNTTTKQFFMSNNISVIYNTVDNVWNNPLTPIEISEPNGMFSAAIELQGVEQSTTALENNSISNVGNNLKQSYIYFIDTDKTQIDGVLESHKADLNSIKISSYDIDLSKALVTGSNPNGVNLEKCIGETLTGISIGLGEEKETIVVKVNDITLSSDKWTSNVFNVDDKIVVESKSQDTVVIKVYKITIKLKQSFVQNEAELRNALQDNCVKQIILEKGITLTNSLDINRNIILDSSGTGR
>NZ_CP011803.1|WP_007059797.1|359903_361373_+|nicotinate-phosphoribosyltransferase
MINPFLLTDFYKTIHHMCYAKGMTKLVSYWTPRMSRKENMNKVVMFGLQSFIKKYLIEYFNENFFNKDKETVVLEYKRIISKTMGEMAADTKHIEALHDLGYLPIQIKAVEEGLRVNIKTPMIEITNTHKDFPWLVNYLETIMSCNIWQPMTSATIAYRYREIVEKYFNLTVENGNVKNACGDFSMRGFSSVESAEFSGAAHLLSFVGTATIPAISYLEKYYNCNVEEELVGLGTPSTEHSVMCSYGEDEFQAYKRLITEVFPSGVLSIVSDTYDYWNVITHILPKLKEDIINRDGKIVIRGDSGDPVKIICGDKEAEKGSNEYKGTVELLWDIFGGEINSKGYKVLNSKIGTIYGDSITVQRCEEICKGLEEKGFAVSNCVFGIGSYTYQYNTRDTFGFALKATHAVIDGKEKFIFKAPKTDKDNFKKSQKGMCYVYRDGQDILYKDELTIEEQEKCKDNLLQVVFKDGKLIKDYSLSEIRNKLYKSF
>NZ_CP011803.1|WP_007064467.1|359091_359889_+|ribose-phosphate-pyrophosphokinase
MIYFNGEKVEFKKFPNGEAMIHSENLKLRINNNEIKVKFENDEDITHLIFLKGHLDELKVKCSLILPYMPYSRMDRTEGIMIFTLKYLCKLINSLNFESVTIYEPHSDVSAALLDRVKVVNMSKILTEHLLKKLNNGKEDVYLVYPDAGAAKRYGKDISYEKILTANKERDFKTGFIKKLDINGSVKSKNFKAIIVDDLCSKGGTFMLAASRLKEMGAGEIYLAVTHLEDTVFQGDLLKNDLIKAIYTTNSILSKEHEKINVYEI
>NZ_CP011803.1|WP_035774366.1|358145_358694_+|NADAR-family-protein
MKYTIDNLKQDFQKGKRIKYLFFWGHQPSRDGGITKTCLSQWWKANFVIDGYTYCCMEQYMMAEKARLFKDNETLDEIMKSSQPKQIKTLGRKVKNFDEELWIKSRYSIIVKGNYAKFTQNENLKEFLIQTKDRVLVEASPYDRIWGIGMSKDDPNIENPLYWKGSNLLGFALMEVRDKILS
>NZ_CP011803.1|WP_007059801.1|357229_358129_+|NUDIX-hydrolase
MEEINIKNKQGLTEEEFLEQYDDSIYQKPSFTVDMLIFTVMDEEKENYRKLPEKSLKILLVKRGDHPCIGKWALPGGFVDVNESLDEAALRVLRAETNIDDIYMEQLYTWGEVNRDPRTRVISSSYMALVDSSSLSIKAGRDEEDAAWFNVRYNLLQEKKEVVEKGYIYEQIVQIKLWNENEELSAKIKVIENPDGKVSREIIGSEGIAFDHDKFIEYAISRLRNKIEYTSLAFNLMPELFTLTELQKVYEVIQGKELLAAAFRRKVANMVIETNQFTKDAGHRPSKLFRYNSGWKRNI
>NZ_CP011803.1|WP_007064470.1|355127_357011_+|PTS-fructose-transporter-subunit-IIABC
MKITELLKKDTIILDLNSSTKSEVIDELVNKLSYAGKLNDKAEYKKAILAREEQFSTGIGDGIAIPHAKTSAVKVPALCFGRSKQGIDYESLDGSDAHIFFMIAASEGAHNDHLDTLSRLSSLLMNEDFRKKLMEASSEDEILTLIDNQEKEYLKEQEPKKEESNTKAEGFILAVTACPTGIAHTYMAADSLKNKAKEMGVDIKVETNGSTGVKNRLTEDEIERADAIIVAADKQVEMARFEGKKVIQVPVVQGIKKPEELINRGLNGDAPVYHHSGSNEGSSSKNERTGFYKHLMNGVSNMLPFVVGGGILIAISFMFGIKAFDPKDPTFSPIAKLLMDIGGGAGAFSLMIPVLAGFIGMSIADRPGFAPAMVGGLLANTSGAGFLGGLIAGFLGGYVVVLLKKVFAGLPQSLEGIKPVLLYPLFGIFITGAIMLLVIASPVKAINTGLTAWLGSMGTTNKVILGLVLGGMMAVDMGGPINKAAYTFGLAMISANNFYPHAAIMAGGMVPPLGIAIATTIFRNKFTEQERDAGKTCYVMGLSFITEGAIPFAAADPGRVLPAAIIGSAVAGALSMMFNIGLPAPHGGIFVIAIVKGSPLLYALAILIGSAITAVLLGILKKPVEEK
>NZ_CP011803.1|WP_007059804.1|354080_354992_+|1-phosphofructokinase
MICTVTFNPSIDYVIKVDDFKPAAVNRVNSENKYPGGKGINVSRVLNNFGIKNKALGFIGGFTGDFIKNSLQNQGVYTDFIEVAGDTRINVKLKSKEETEINGAGPIIKQEDLNKLFEKIEALNSDDYLVLAGNVQKSLPANVYSLIQEKCLGKKVKVVVDTTGEALTSTLKYKPFLIKPNNHELGEIFGVEIETREEIIKYAQKLRDMGAENIIISMASKGALLLCDEGVYQASAPKGTVKNSVGAGDSMIAGFLASYSQNLNLVEALKYGAASGSATAFSMDLCKKQEVEALLKEIIITKI
>NZ_CP011803.1|WP_007059805.1|353462_353750_-|hypothetical-protein
MIGNFISPPPSSAPPNFIPVKSKGINNIDLTGLNVHGNVLKPLMFKHIYMWLRDGSEFWCWISYISGSHLGGFRWDGSNWVGFEIDLRKIDVYSN
>NZ_CP011803.1|WP_007059806.1|352043_353414_+|D-serine-ammonia-lyase
MESKIIQGKSIREWKKQYPLMNKIISTEEVFWTNSKYGKFEDAIKKVSLTEEDVKDAEERLKRFAPYIAKVFPETQKTNGIIESPVVKIPNMQRKIEEMFNKEVLGELLLKCDSHLAISGSIKARGGIYEVLKHAEDLAIENNMLTIEEDYSILDSDKFRKFFSKNSIAVGSTGNLGLSIGIMSAQLGFKVYVHMSADAKQWKKDLLRSKGVTVVEYASDYSKAVEEGRKQAEADPNMYFVDDENSTNLFLGYAVAAYRLKKQLEEINVVVDEEHPLFVYLPCGVGGGPGGVAFGLKLVFKDNVHCFFAEPTHSPCMLIGLMTDMHDKVCVQDFGIDNITAADGLAVGRASGFVGKTLKNLISGAYTAKDEKLYVLLSTLIDSENIYLEPSALAGIPGCIELFKDEAGKKYIENNNLKDKMKNASHIAWATGGSMVPKDVMETYYKKGKELSSHKI
>NZ_CP011803.1|WP_007059807.1|351070_351970_+|fumarylacetoacetate-hydrolase-family-protein
MKFVTYEFEGKESIGIMRGDKIVSIEDIANCMSWEEPKNMVELIEKYTEDMLDKVENILEKRGDFKLLSLDDVKIKAPIPYPKRNVLCLGKNYVEHAREIKITRIAGTGIPEEPIYFTKVASPAIGHEDEIKFSYEVTKQVDYEVELAIIIGKDGINIKKEDAEDYIFGYTIVNDVSARDLQGKHKQWFKGKSLDTFCPMGPCIVHKKDIPFPVELNIKCSVNGELRQNSNTKNLIFDIPYIISDLSKGMTLKAGDIICTGTPSGVGLGFEPIKVLKDGDTVECSIEKIGELVNKVKVI
>NZ_CP011803.1|WP_007059794.1|367985_368741_-|TSUP-family-transporter
MDNNLIFLCTACFFAAFVDSISGGGGIISLPAYLLAGIPPHLALGTNKFTSCCSTFSSSIKFAQSKKVDFNILKYLIPFSFIGGILGATTVLRIKTSYLNTIVPILLLFVGLYSLFSKNIGMEDRFKNISRKNITLGIILALFLGFYDGFLGAGVGTFLIFGLIKIYNFNFIRAGGNCKVMNFVGNIASIIVFAVRGEINYKIGLPVAVFMVIGAHLGAKIALRKGSKIIKPIFVTMSLAIAAKLLYSMTL
>NZ_CP011803.1|WP_007059793.1|368949_369813_+|LysR-family-transcriptional-regulator
MDIRQLKYFLAIAEEENITRAAEKLHIAQPPLSHQLKLLEYELGVKLIDRSTRKIQLTDTGEKLRYRAEQMLNLMETTVRELKDINEGVQGTLLIGTVPSSGATLLPERIHSFHEKYPGIDFQIWDGDTYRIMELLSSGTIEIGIIRTPFNSKIYESICLPKEPMVTASSNSYSYNKQGSLEIAELVDTPLVIDRRFEKVIVDAFEKERVKPKIICRGDDVRSILLWASTGIGVAIVPKAATGLIPNSNLNYRKINLTSVETQTAIIWMKNRYLSSAARHFLKTFKE
>NZ_CP011803.1|WP_007059792.1|370021_370198_+|aspartyl-phosphate-phosphatase-Spo0E-family-protein
MDRVEQLLKKIEETRTYMNDLIKEKSDLLDPEVIIVSQMLDSILDEYYKILQQENIRK
>NZ_CP011803.1|WP_007064464.1|370445_371240_+|HAD-family-hydrolase
MIKLIASDMDGTLVNDEGKINEKMFELINNLHEKNIKFAAASGRFYSQLSKNFEKIKTSIIFISHNGALVKFNNKGQTLYSSCISSQDIEHVANLKRDFGEKLFLAAADDAYMVNPSQALLDEFKFYDIPLVIIKSFKEVKSPIYRMTYYTKDGVKPETVEYLKNNLNENLEFVVSGGKWIDIMNKGTSKGNAIKILQQKFGINENNTMVFGDYYNDLSMFKEAYYSYAMENAPEDVKKHANFIAENNNKNGVYNVINKYAASI
>NZ_CP011803.1|WP_007059789.1|371322_371778_-|CBS-domain-containing-protein
MQAHEIMITEVYTVNENDLVRSVIKKFIKYRISGIPITNSKNQIVAYVSDGDIMRYIGKHENLVVDFLYYVSAAKGDDDEFEDRLQKILNLNIMDIAQRKVIKVNMNEDIENVASILAKKSIKKLPVEHNGVLVGIISRGDVIRNCFKSIL
>NZ_CP011803.1|WP_007064462.1|372078_373380_+|glycosyltransferase-family-39-protein
MKSIDKITASTLFLEKNYYKSITMLGILICVIWAAVVNTKPFSDFAYYDEVARQIAAGGAWGDTYTSVGYSIVLGGIYKIFGSSLIVAKIFNLILTFFNYILMYNILKSVELKENKRKLVYALFVFFPDNIFYNSILATEILFTTILLLITLIYHKNIKHKYIIIGALTGMNTMIKPFFMIFFFAIFVIEIILKFKFIKVIKHSLIVLITSALVISPWIYRNTKLIGQFTYVSNNSGIVLYINNNSQNHYGAWMPASEVEDSIVNKKEYKKANMTEKNNMLSDAAKKWIKEHPVQFVQLGFKRLYKTYLIGYSITYSFNGAGLNKITENILTAYSSAISILVAAVSIIVMIMYSKKVICSIFNKEKVNSYSVYSLICFYMFSCMYFITEGQPRYAFPVIFIMIYFFSDLIGIKKFRQEKIDSDHNALFTKSNL
>NZ_CP011803.1|WP_007059786.1|373794_375951_-|formate-dehydrogenase-subunit-alpha
MEEKVLTVCPYCGAGCNLYLVVEDGKIKRAEPANGRTNEGELCLKGYYGWDFLNDPQLLTARIRKPMLRKNDQLVEVTWDEAIKFTAEKLTYIKNKYGADSIMGTGCSRGPGNETNYVMQKFMRAVIGTNNVDNCARVCHGPSVAGLATVLGNGAMSNTIPEIENADLLLIFGYNPAESHPIVARRVVKAKEKGAKIIVVDPRVTESVRISDLWLQLKGGTNMALVNGFANVLLNENLYNKEYVSKYTEGFDEYKAMVNKYNPEYVENITNVSSEKIREAMRMYSSAKNPMILYGMGVCQFGQAVDVVKGLAALALMTGNYGRPSVGIGPVRGQNNVQGSCDMGAIPNCFPGYQKVTDKAVREKFQKAWGVKLSDKVGYHLTEVPKLVLKENKLKAYYIMGEDTVQSDPNSNEVKEALDKLELVIVQDIFMNKTALHADVILPATSWGEHEGVYSAADRGFQRFRKAVEAIGEAKPDWQIISELSTAMGYPMHYNNTKEIWDEMRSLSPKFAGASYERMEKLGGIVWPCPSEDHPGTPVLYENNIFSTPSGKGILFAAEWRPTEESPDKEYPLSLCTVREIGHYSVRTMTGNCRTLKMLEDEPGKIQMSPEDAKKLKIKDGDLVKVTSRRGSVMSRALVTDRVRSGDTYMTYQWWIGACNELTCDNLDPISKTPEYKYCAIKVEPFPNQALAEKELAQKYTELRKKMGVTKDTYEVNA
>NZ_CP011803.1|WP_007059785.1|376192_376948_+|proline-reductase-cluster-protein-PrdD
MNKELRKLVIKTFHIEKIMFDEKTYIKNNVLFLKEGLENQAVENEDIIKNVHIKIIQPDDKQVWVNSIMDFYPIATKVQGRLGEGVTNLITGIVVMLTGADELGIPQGKFGWSPGYLKDIVYFNRRGTPSSTDIILNIDVNLKTGRGISRSDITTVHRVCDKIVQEIRYYLKNVDSSLCDEVHEFVDKVKTEKKKVIILKQVAAQGAMYNNQLFPKEPCGVIGSKSIIDCGSLPVVLSPNEYRDGALRVMT
>NZ_CP011803.1|WP_007064461.1|377002_377968_+|DMT-family-transporter
MKDRKIFTNTKFVAVIATICCLLWGSAYPAIKIGYKLFNISSSNISSELVFAGYRFTIAGIILLIIAQKYRKKVFDISKKNILELSLLGFTQTTLQYIFFYIGVANTTGVKSSIMNSTVTFFSVILAHYIYVDDKLNMQKIIGCTAGFIGVMIVNFSSDLLNFSFSFQGEGFVIIAAFIFSASAIYGKKLTKSMDVIIITGYSLFIGGLMLILIGVLFKGRVYNFTVESSLLLIYLALLSSAAFSLWNLLLKYNKVGPVSMFNFLTPIFGAVLSAIFLKESIFEIKNIAALILVCLGIWMVNREKISIFQSPTIISNCKKY
>NZ_CP011803.1|WP_007059783.1|378188_379514_+|amidase-domain-containing-protein
MIKRHKHVIFFILIISSIFGYKVKFNYAKGMQLKNSTEIKDEKLSYNILNANKCNQKNIQISNLARYKFVQCNIEPNSENQGKTDPNKKNSIENIDENQLKSEVERIYNARSAAFVSGDVSSLKELFDTSQRYGKWALEHEIKRVKYLNDWSNERNITFGKVTSAVRIKKIYPKGNIIKMALQESYKFDYVYNNDDNSPINSFGVGIRHTTSLIKKNDKWVIYNDWYTDCFEDALLGYSNVADSILRMLPNIHDSNNGHEALSYSRPFYDREKAVAYADKYCGAAWGSSNNFKYNKKYSDYNGIGGDCSNFASQVLGDKEGGGMPIGGSWTPGSRAWSNADGLKNYLTGSGRGSVISVGTFKELTESSERLPSGAIGKVQLGDLVAYEKGRGNVDHFGVITGFDSHGYPLVNSHTTDRYHVPWDLGWGDAKIRFFLIHING

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Crispr_ID: NZ_CP011803_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP011803_2

4122445-4122657

Orphan

Consensus_repeat	Method
TGATTAAAAGTCAGGTGCTCTACCAACTGAGCTAAT	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP011803_2

>merge|NZ_CP011803|2|4122445-4122657|PILER-CR
TGATTAAAAGTCATGTGCTCTACCAACTGAGCTAGTAAACCATATTTATGTTAAAGTGGGGTGGACGAAGGGACTCGAACCCTCGACAACCAGAACCACAATCTGGCGCTCTACCAACTGAACTACGTCCACCATAAAAAAATGGTGCGCCATCAGGGACTCGAACCCTGGGCACCCTGATTAAGAGTCAGGTGCTCTACCAACTGAGCTAAT

>NZ_CP011803|2|1|4122445-4122657|PILER-CR
TGATTAAAAGTCATGTGCTCTACCAACTGAGCTAGT	AAACCATATTTATGTTAAAGTGGGGTGGACGAAGGGACTCGAACCCTCGACAACCAGAACCACAA
TCTGGCGCTCTACCAACTGAACTACGTCCACCATAA	AAAAATGGTGCGCCATCAGGGACTCGAACCCTGGGCACCCTGATTAAGAG
TCAGGTGCTCTACCAACTGAGCTAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP011803.1\|WP_179945255.1\|4130686_4132687_-\|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl\|CDD\|236137
NZ_CP011803.1\|WP_007063820.1\|4111471_4112344_-\|orotidine-5'-phosphate-decarboxylase	unknown	unknown	gnl\|CDD\|234651
NZ_CP011803.1\|WP_007064163.1\|4116503_4117763_-\|2-hydroxyacyl-CoA-dehydratase	unknown	unknown	gnl\|CDD\|377594
NZ_CP011803.1\|WP_007064103.1\|4124607_4125357_-\|ribonuclease-PH	unknown	unknown	gnl\|CDD\|178914
NZ_CP011803.1\|WP_007062272.1\|4130311_4130581_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011803.1\|WP_007064161.1\|4119309_4120524_-\|threonine-ammonia-lyase	unknown	unknown	gnl\|CDD\|236182
NZ_CP011803.1\|WP_007063817.1\|4114261_4115182_-\|aspartate-carbamoyltransferase	unknown	unknown	gnl\|CDD\|234849
NZ_CP011803.1\|WP_007064102.1\|4125403_4126393_-\|AIR-synthase-family-protein	unknown	unknown	gnl\|CDD\|100037
NZ_CP011803.1\|WP_007064100.1\|4128000_4129602_-\|peptide-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173869
NZ_CP011803.1\|WP_007063821.1\|4110689_4111430_-\|dihydroorotate-dehydrogenase-electron-transfer-subunit	unknown	unknown	gnl\|CDD\|234601
NZ_CP011803.1\|WP_007064162.1\|4117878_4119027_-\|2-hydroxyacyl-CoA-dehydratase	unknown	unknown	gnl\|CDD\|377594
NZ_CP011803.1\|WP_007064105.1\|4123531_4124002_-\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|223695
NZ_CP011803.1\|WP_007063816.1\|4115405_4116164_-\|CoA-activase	unknown	unknown	gnl\|CDD\|129344
NZ_CP011803.1\|WP_007062273.1\|4129701_4130127_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011803.1\|WP_007064101.1\|4126488_4127877_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP011803.1\|WP_007064104.1\|4124005_4124611_-\|XTP/dITP-diphosphatase	unknown	unknown	gnl\|CDD\|234648
NZ_CP011803.1\|WP_007062270.1\|4132713_4134978_-\|DNA-helicase-PcrA	unknown	unknown	gnl\|CDD\|273429
NZ_CP011803.1\|WP_048030338.1\|4116235_4116487_-\|DUF3343-domain-containing-protein	unknown	unknown	gnl\|CDD\|378728
NZ_CP011803.1\|WP_007063818.1\|4113809_4114241_-\|aspartate-carbamoyltransferase-regulatory-subunit	unknown	unknown	gnl\|CDD\|234859
NZ_CP011803.1\|WP_007063819.1\|4112392_4113577_-\|dihydroorotase	unknown	unknown	gnl\|CDD\|236479

Protein	Function_ID	Function_description	E-value
NZ_CP011803.1\|WP_179945255.1\|4130686_4132687_-\|NAD-dependent-DNA-ligase-LigA	gnl\|CDD\|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NZ_CP011803.1\|WP_007063820.1\|4111471_4112344_-\|orotidine-5'-phosphate-decarboxylase	gnl\|CDD\|234651	PRK00125, pyrF, orotidine 5'-phosphate decarboxylase; Reviewed.	6.60441e-149
NZ_CP011803.1\|WP_007064163.1\|4116503_4117763_-\|2-hydroxyacyl-CoA-dehydratase	gnl\|CDD\|377594	pfam06050, HGD-D, 2-hydroxyglutaryl-CoA dehydratase, D-component. Degradation of glutamate via the hydroxyglutarate pathway involves the syn-elimination of water from 2-hydroxyglutaryl-CoA. This anaerobic process is catalyzed by 2-hydroxyglutaryl-CoA dehydratase, an enzyme with two components (A and D) that reversibly associate during reaction cycles. This component contains one non-reducible [4Fe-4S]2+ cluster and a reduced riboflavin 5'-monophosphate.	4.10225e-152
NZ_CP011803.1\|WP_007064103.1\|4124607_4125357_-\|ribonuclease-PH	gnl\|CDD\|178914	PRK00173, rph, ribonuclease PH; Reviewed.	7.19202e-162
NZ_CP011803.1\|WP_007064161.1\|4119309_4120524_-\|threonine-ammonia-lyase	gnl\|CDD\|236182	PRK08198, PRK08198, threonine dehydratase; Provisional.	0
NZ_CP011803.1\|WP_007063817.1\|4114261_4115182_-\|aspartate-carbamoyltransferase	gnl\|CDD\|234849	PRK00856, pyrB, aspartate carbamoyltransferase catalytic subunit.	6.68188e-149
NZ_CP011803.1\|WP_007064102.1\|4125403_4126393_-\|AIR-synthase-family-protein	gnl\|CDD\|100037	cd06061, PurM-like1, AIR synthase (PurM) related protein, subgroup 1 of unknown function. The family of PurM related proteins includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM synthase and Selenophosphate synthetase (SelD). They all contain two conserved domains and seem to dimerize. The N-terminal domain forms the dimer interface and is a putative ATP binding domain.	1.1301e-131
NZ_CP011803.1\|WP_007064100.1\|4128000_4129602_-\|peptide-ABC-transporter-substrate-binding-protein	gnl\|CDD\|173869	cd08504, PBP2_OppA, The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding component of an ATP-binding cassette (ABC)-type oligopeptide transport system comprised of 5 subunits. The transport system OppABCDEF contains two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	2.06287e-130
NZ_CP011803.1\|WP_007063821.1\|4110689_4111430_-\|dihydroorotate-dehydrogenase-electron-transfer-subunit	gnl\|CDD\|234601	PRK00054, PRK00054, dihydroorotate dehydrogenase electron transfer subunit; Reviewed.	4.63623e-113
NZ_CP011803.1\|WP_007064162.1\|4117878_4119027_-\|2-hydroxyacyl-CoA-dehydratase	gnl\|CDD\|377594	pfam06050, HGD-D, 2-hydroxyglutaryl-CoA dehydratase, D-component. Degradation of glutamate via the hydroxyglutarate pathway involves the syn-elimination of water from 2-hydroxyglutaryl-CoA. This anaerobic process is catalyzed by 2-hydroxyglutaryl-CoA dehydratase, an enzyme with two components (A and D) that reversibly associate during reaction cycles. This component contains one non-reducible [4Fe-4S]2+ cluster and a reduced riboflavin 5'-monophosphate.	1.83717e-141
NZ_CP011803.1\|WP_007064105.1\|4123531_4124002_-\|metallophosphoesterase	gnl\|CDD\|223695	COG0622, COG0622, Predicted phosphoesterase [General function prediction only].	3.86389e-44
NZ_CP011803.1\|WP_007063816.1\|4115405_4116164_-\|CoA-activase	gnl\|CDD\|129344	TIGR00241, Uncharacterized_protein_MJ0004, CoA-substrate-specific enzyme activase, putative. This domain is found in a set of closely related proteins including the (R)-2-hydroxyglutaryl-CoA dehydratase activase of Acidaminococcus fermentans, in longer proteins from M. jannaschii and M. thermoautotrophicum that share an additional N-terminal domain, in a protein described as a subunit of the benzoyl-CoA reductase of Rhodopseudomonas palustris, and in two repeats of an uncharacterized protein of Aquifex aeolicus.This domain may be involved in generating or regenerating the active sites of enzymes related to (R)-2-hydroxyglutaryl-CoA dehydratase and benzoyl-CoA reductase.	2.42511e-73
NZ_CP011803.1\|WP_007064104.1\|4124005_4124611_-\|XTP/dITP-diphosphatase	gnl\|CDD\|234648	PRK00120, PRK00120, dITP/XTP pyrophosphatase; Reviewed.	4.90677e-99
NZ_CP011803.1\|WP_007062270.1\|4132713_4134978_-\|DNA-helicase-PcrA	gnl\|CDD\|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_CP011803.1\|WP_048030338.1\|4116235_4116487_-\|DUF3343-domain-containing-protein	gnl\|CDD\|378728	pfam11823, DUF3343, Protein of unknown function (DUF3343). This family of proteins are functionally uncharacterized. This protein is found in bacteria and archaea. Proteins in this family are typically between 78 to 102 amino acids in length.	4.56525e-24
NZ_CP011803.1\|WP_007063818.1\|4113809_4114241_-\|aspartate-carbamoyltransferase-regulatory-subunit	gnl\|CDD\|234859	PRK00893, PRK00893, aspartate carbamoyltransferase regulatory subunit; Reviewed.	5.67138e-62
NZ_CP011803.1\|WP_007063819.1\|4112392_4113577_-\|dihydroorotase	gnl\|CDD\|236479	PRK09357, pyrC, dihydroorotase; Validated.	1.0163e-156

>NZ_CP011803.1|WP_007064161.1|4119309_4120524_-|threonine-ammonia-lyase
MELNLERIKKAQENIKEVVRKTPMFHTSTFSKKCNCNVYLKCENKQKTGAFKLRGAYNKLVNLTEEEKKRGVIASSAGNHAQGVAFAATSFNVKSTIVMPLTAPQAKVAATKGYGAEVIQAGQVYDECHDKAVEVQKETGATFLEPFNDIDVMAGQGTIALEMLEDLPEADVIVVPIGGGGLISGIAVAAKSIKPSIRIVGVEPEIVPSAKAALEKGKVTTVPGAKSLADGISVSTLGDECFKYIQKYVDEVVTISEDEIAHAMFQIMERNKLIVEGSGAAPLAALLAKKIDGIEGKNVIALVSGGNADIATTAKIIERELVFEKRRIRFEAELQDKAGTLGALISEVGAMGGNVVTVRQNSNWNERGLESADVSFEITVQSQEHGESIIKSLRDKGYVINIKK
>NZ_CP011803.1|WP_007064162.1|4117878_4119027_-|2-hydroxyacyl-CoA-dehydratase
MNELPEKINEFGEKRRKGFVTIKNLKDEGKKVVGVFCAFTPKEVISAAGAIPIGICGTSEEPIPDAEKHLPRNLCPLIKSSYGFAITEKCPYTYFSDLIVGETTCDGKKKMYEMLGKIKDVHVMQLPQTTKGEDSYKLWKNEIIKLKEKLEKKFDVEITEQNLKDAIKLKNRERETLREFYELGKMTPPPIEGIDILKVLRGAAFSYDKEEEIKTISDMTKSIKETYGKGEKKVSSSAKRILVTGCPLGESTDKIINTIEQNGGVVVCFENCGGVKDIGFLVDETIDPIDALTSKYLNIACSCMTPNNNRIELLSKLIDEYKVDGVVDVILQACHTYNVETYTIKEFVTKEKNIPYLSIETDYSQTDIGQLKTRIGAFIEMI
>NZ_CP011803.1|WP_007064163.1|4116503_4117763_-|2-hydroxyacyl-CoA-dehydratase
MGDYRQLWTDLGVDLEKHDKLCAVLPELYGDTYLTQENRPEGMNYFNFVVAEVHGLRIQELDEHRRKGGKVIGTFCVFVPDEVILAANAIGVGLCAGSQFWIEDGEKVLPRNMCPLIKAFMGAKVGGTCPYFQSCDMIIGETTCDGKKKAWEVLEDYVPVHVMDLPQMKRAKDYTAWSSEIKDVIAKVEELTGNKVTVDSLKEAIRTANAKRRALKRLYDLRKYKPSPISGLDCLLISQIAFYDDPHRFVEKLNELCDELDERVKNLKDQGKKRLMITGTPMALPNWKLHSIIEGLNAQVVVEETCTGTRYFENEVSEEGETIDDLIKNLADRYLNINCACFTPNTGRIDDIIKYSKEYDVDGVIDFNLSFCHTYAVEHKAVEKALKEKDIPVMHIETDYSTEDAGQIKTRVEAFLEMI
>NZ_CP011803.1|WP_048030338.1|4116235_4116487_-|DUF3343-domain-containing-protein
MQQIRHYILFPSHTEGMKLEKVLKEQKIKYTIVPTPRQLSTCCGISIMYNKEDEDKIKTLIDMHNVKTLGFHSVDRKVKNPYL
>NZ_CP011803.1|WP_007063816.1|4115405_4116164_-|CoA-activase
MFYVGIDIGSTASKVCIFNGDEMENTFVLPTGWSSVKTAEDIKERLEELNLNKDNSRIVATGYGRVSVPYADKTVTEITCHGKGAYYILGEDCTVVDIGGQDTKVITVQDGKVTNFTMNDKCAAGTGRFLELMANTLGLSITEMCEMSEQGEEITISSMCTVFAESEVISLIGSGKRREDIACGVVDSIASKVKSLCQKHSDSFNYFLTGGLSTNKYIIKKLSEKLQSKVKADELGRYAGAIGAALVAKSLK
>NZ_CP011803.1|WP_007063817.1|4114261_4115182_-|aspartate-carbamoyltransferase
MLKGRNLIDPMDFTLEELEEIFKLADQIISNPEDFTHICQGKLLATLFYEPSTRTRFSFEAAMIRLGGQVIGFSEPNSSSVSKGESVADTIRTVGCYADIVAMRHPKEGAPKVAAINSPIPVINAGDGGHQHPTQTLTDLLTIKSIKGRLSNLKIGLCGDLKFGRTVHSLIKAISRYQNNKFVLIAPKELKVPEYIIKELNKNNIEYKEVEKLEDVIGDLDILYMTRVQKERFFNEEDYIRLKDSYILDEAKMSIASEDMIVLHPLPRVNEIAYEVDDDPRACYFKQAKYGMYVRMALIAKLLGVR
>NZ_CP011803.1|WP_007063818.1|4113809_4114241_-|aspartate-carbamoyltransferase-regulatory-subunit
MLTINSVRNGIVIDHIKAGHGIKIFNYLGLDNAEYSVALIMNAESKKCGKKDIIKIENNLELDLKVLGFIDPNITIDIIEDEQIKEKIKLKLPEKVENIIKCKNPRCITSVERDLAHVFYLTDEEHGEYRCLYCDETYRVSDM
>NZ_CP011803.1|WP_007063819.1|4112392_4113577_-|dihydroorotase
MELLIKNAKIVDWSQNFIGDVYINEGIICEMGKNLKKDCKIIDAEGLTLLPSFIDLHVHFREPGFTNKEDIESGSYAAAKGGYTMVNLMANTKPVCSSMDTINYVLNRAKEVGIIDVHQVSSITNNFDGKDISHLDRLDPSVKIISEDGNDVMDSKVMLEAMVKAKESGRIVMCHCEEHLLSNIDTRLSENTMTWRNIALAEFTGCAVHIAHVSTKESMEYIIEAKKKGINVTCEVAPHHIALVDNDYRVNPPIREKEDVEFLIKSIKDGWVDAIGTDHAPHTAEDKKNGSPGISGIETAFSVCYTKLVKEEKISFSKLSEIMSRNPAYIMGVKKGQIKIGYDADLVLVDTERKYEICSDTFKSKGKNTPFNGTKVYGAVVRTLKSGNTVFSEM
>NZ_CP011803.1|WP_007063820.1|4111471_4112344_-|orotidine-5'-phosphate-decarboxylase
MIIDKLFESVEKNGHVCVGLDTDVEYIPKWVINKNTSIEDAIFEYNKNIIDATLDVASCYKVQIAYYEALGISGLMVYKKTLEYIRSKKAIVIADIKRGDIAKTAEMYARAHFEGDFESDFVTLNPYMGLDGVEPYLPYVKNKEKGLFLLVRTSNKGAEDIQYVDTKEKEKVYNVVGEKIQQIGEQCMGSCGYSSIGGVVGCTHVEEGIKLRADLNKMFFLIPGYGAQGGKAEDVALYLHQGNGGVVNSSRGILLAYKKVEDGEKNYAECARKEAVRMRDDILSKLKINS
>NZ_CP011803.1|WP_007063821.1|4110689_4111430_-|dihydroorotate-dehydrogenase-electron-transfer-subunit
MEKVKMNYSTEKVYENIEIENPVYKLTIKGKFNGKPGQFYMLKCWNKEPILSRPISINHIDEEKIVFLYQVVGEGTEILSKLKKAETVEIMGPLGNGFDIDNIKGKVAIVSGGIGTAPMEYVAESLKECKVDLYAGFRDKSYIIDEFKGIVENVNISTETGREGHKGYITDIFKPELYDVVLCCGPEIMMNKVIKLCKDKNVKVYVSMEKHMACGVGACLVCTCKTKNGNKRTCKDGPVFSGEDII
>NZ_CP011803.1|WP_007064105.1|4123531_4124002_-|metallophosphoesterase
MKIGVISDTHRYIWVIENAIKKIGDVDVLIHLGDNVQDVKEIKKYYKGKIINVKGNCDFAVDVPSEKTEVIADKRVFITHGHRYDVKYDLSRIRYKALEVKADIVLFGHTHVSQIAYEDGIWFVNPGSPAVPRDEFYSVAIIEIKDGKINPGIKGV
>NZ_CP011803.1|WP_007064104.1|4124005_4124611_-|XTP/dITP-diphosphatase
MKKLIVASNNKNKIIEIKEILSKYSIEVLSLKEANINIDVEEDGTTFMENAYKKANEIHKILKNEMVLADDSGLVVDCLDGAPGVYSARFAGEHGNNKKNNKKLLELLKEKDDKDKKAKFVCAMVLISDTGKVIKVQGEIEGIIINEERGSNGFGYDPVFYIPEYKMTFAQMKSDLKNSISHRANALKELEREIINLMGDE
>NZ_CP011803.1|WP_007064103.1|4124607_4125357_-|ribonuclease-PH
MRIDGRKNDQIRHTKITRNYTKYAEGSVLIEAGDTKVICTASIEDKVPPFLKGKGEGWITCEYNMIPRSTKVRKVRDINRGKIDGRTMEIQRIIGRALRSVVDLKSIGEKTIWIDCDVIQADGGTRTASISGAFIALVDAVNKLHKQTPFNVYPVRDFVGAISVGIVGNVKMLDLCYEEDSKANVDMNVVMTDSGEFIEIQGTGEEKPFSKQDLSELLSLAEQGINHVIQIEKESLKMDSLWIGTGERK
>NZ_CP011803.1|WP_007064102.1|4125403_4126393_-|AIR-synthase-family-protein
MKVGKLNWDDLKNIIDDSRGAIRNDVRIRSGIGEDCSVIDFGEYECVVSTDPITGAEKNSGKLAVNINCNDIASAGVEPLGILVTILAPEGSSLEDIKSVMKEIGEETKKLNVEILGGHTEITRAVNKMVISCTVIGKGLKNKSIATSGAKENDDIIVTKLLCLEGTGIVVNDHEDKIKGILTHEEIAEAKTYLNSLSVVREGAIAGKFGVNSMHDITEGGVLGALWEVAKASNLGFRVYKEKMPISHVTEKICKKYSIDPLRLISSGSMLITTKNGDKLIGVLKEEGIEASIIGKIVKQKGVLIEGNIEKEVLPPERDELFVLEERIM
>NZ_CP011803.1|WP_007064101.1|4126488_4127877_+|hypothetical-protein
MKYIGPFLRINKLKKENIEHQLFFLAKESLNQIVLHSKCGVYTSIKELKIKSLSSSDINTFGNVSPLLCLYKKGNPKITNIDDNLCWNAESFKREINVDSNAFMTLSLLELCNYYKQFEGINNKKFNLTKLYMCICKNQLDFYATHFRNADGVFVDKKESKDSYNEEVSFEEKNKKFKFSSQALFMDAYYRYASLSDDDEKVSYENFALDILNMFIEFKEDIYTLSLDEILKLTLSLNIFYGYSKNKQCKLLLLDLCELIYDRFNNTNTPLISYDDKLEYDCLKYINFFLFYKNTGIIKFKEDAEKIHNKLLNLYDPEKGIFIKHTEKKDITFSCIEISLYLLICLIHENISKEQSDNNLIILDVFKRQLIDSGIILSWPDIPDLNDIERYKNYTLKSEDLIDEQYFRSSSLPTPESCEITSVFVKHVVYSRKKETFEPSKTSFDSYKNMVIFFLIIYLLKS
>NZ_CP011803.1|WP_007064100.1|4128000_4129602_-|peptide-ABC-transporter-substrate-binding-protein
MKKIICCLLIISFMFFNGCVEKDVQTSKSEQIRNYIVYNIGKMPKDLFMLNDSNIRQQDLLNNLFEGLVRVDDTGKITPAIAQSWTLSKDETCYTFKIKDNAKWSDGTYITAEDFVNFFKEILSKDVENIYAEQLYCIFGSENYRSGKTDFNNVAIRALDKKSLEIRLNYPCCYFLNLLAQPIYGIRKIDANLKDWSKNYKNILYSGYFTISDFKNNNEMMLIKNKNYWNKDGVKSDKICITFNDGSEASLAAFQNSKINLFTNPPISEVKNLMNKGSIIEQQSLSVGALVFNLKRDTIVKDVNFRKAVSECIDRNAISKNILNDSAKPGLSFIPQGVSNGVNGVYINKEFFSASIQKDKALNFIKNSKYNKDSDPLKIIYLDTVENKKICENVAKNLRDNLQIKVECESYGTEELKDEIKKGDYDMAKIQYEAVYNYPLSFLEQWQSSSKNNVYGYGNIVFDNMVAKARIESDESKKIAELRTAEDILMEELPVIPMYFNKILVCKKYNIKGVSINQRGNLDFHNLEIVTEA
>NZ_CP011803.1|WP_007062273.1|4129701_4130127_-|hypothetical-protein
MNNLFHKSCFIGQKTEFYKMKLKKVSINEISDNITKSCWNYNIQYEMILKDSHTLLIDLIGKEKEILLKYHKKDIITKNDYEGFINYLENYEIERGIYITTGFFEKHIYDNLHKKVKKIDVKKFIKNQPNIDKLSFLQYLP
>NZ_CP011803.1|WP_007062272.1|4130311_4130581_-|hypothetical-protein
MKKTINLLGWIGVCLTILTLVLTLLTTYQFTYVKYFNSYYTMQWCIFFTMLIWAAKMFDFKANRNDIVCPVTCVLIAIGTIFFIFMKVY
>NZ_CP011803.1|WP_179945255.1|4130686_4132687_-|NAD-dependent-DNA-ligase-LigA
MDTKKEQIEKLVEELNKYAQEYYLLDNPSVSDKEYDLRYDELLKLEKETGIILPYSPTQRVGDNILKEFQKYTHKGKLWSLDKSQTVQGIIDWHVRNKKAVDDYNSTHEEKLPQLEYVITKKFDGLTINCTYDENGILIKAATRGTGEVGEDITAQARTIMSLPLKINNSNVIEVHGEAIMTREAFEEYNKSAAVPLKNLRNGAAGALRNLNIKETARRKLSAFFYDVGYNEGAPFKTYFEMMNFIKNMGFPLDNYIKICSSIEEIENELKYVEEIRSELNYDIDGVVIAINDMKTREILGYTIKFPKWAIAYKFEAEEATTKLLDVEWNVGRSGRVTPTAILEPVELAGVTVKRATLNNMDDIKRKEVRIGCSVFVRRSNDVIPEIMGVVQDTLEGSIEIQAPEKCPYCDSELVQDGVHYFCDNTLSCKPQMVKSIVHFGSREAMNIEGFSEKTAEQLFEKLEIKSIPDLYRIKKEDLMQLDKFAEKKAQNLVNAIEKSKNCSLASFIYALGIPNIGKKTATDLVKNFKSLDNIIQSSEEELVSIQDVGEIVAKSIIEFFNEDKIINSINELLELGVKPIFEEEEVSKSLFSDKTVVVTGSLENYTRTTIKEKLQSVGAKVSGSVSKKTDYVLAGKEAGSKYDKALELGVKIINEEEFEKMLSKL
>NZ_CP011803.1|WP_007062270.1|4132713_4134978_-|DNA-helicase-PcrA
MDLKMLLNKEQYEAAVQVNGPLLILAGAGSGKTRVLTYRIAHMINDLNIYPSKILAITFTNKAAGEMKDRVRSLVGNEADNMWVSTFHSSCVRILRREIDKLGYNKNFAIYDTYDQKILIKQCMDELNINDKDITDREIINKIGEQKDNLISPDRYKKENEGNYRLNKIADAYMLYQKKLKSNNALDFDDLIYKTVELFKKNEEVLDFYQRKFQYVMVDEYQDTNKSQYELVKLLATKHRNICVVGDDDQCIYAWRGADIKNILGFEKDYPEAKVIKLEQNYRSKGNILKAANDVIKNNAERKRKVLRTENEDGERIKIYRAYSDMEEANYVASQIRKITKDNNKKYKDFAVLYRTNAQSRTFEDIFMKSNIPYRIIGGLKFYDRKEIKDILAYLKFVNNPLDDVSLRRIINVPKRSIGDATVKKVQEFANSMEECMYSVLLDIEQVPSIPTRGTASIKKFVSLINSFIRSKDEIAVSSLIKEILDTTGYLEELKDSQDIDALSRIENLKELVSAAVEFESTSEDKSLSAFLEKVTLVSDIDNFNEDADTVVMMTVHSAKGLEFPVVFMVGMENGIFPGSQSLNDFSEMEESRRLCYVGITRAKEQLYMTSAEQRRVFGRTVSYSESDFIGEISKDLRENDNMTARNTIKSKSFSTYSNRSTTITNSVTSHMNRSVNNSMPSSFGESSLNKNKENANSLKIEDIKAGLKVKHDKFGIGTIVGVSKSGEYTKLTIVFDKAGIKNLMYGVASLEFV

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

2633584 : 2648774

Clostridium_botulinum_C_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007064062.1\|2633584_2634439_-	energy-coupling factor ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	4.6e-12	31.1
WP_007064061.1\|2634451_2635300_-	cobalt ECF transporter T component CbiQ	NA	NA	NA	NA
WP_007064060.1\|2635354_2636134_-	precorrin-6A reductase	NA	NA	NA	NA
WP_007060306.1\|2637012_2638086_-	hypothetical protein	Q332K3	Clostridium_botulinum_C_phage	2.2e-88	49.1
WP_007060305.1\|2638085_2639264_-	hypothetical protein	Q332K7	Clostridium_botulinum_C_phage	3.0e-38	42.9
WP_007060304.1\|2639275_2640031_-	CRISPR-associated endoribonuclease Cas6	Q332K8	Clostridium_botulinum_C_phage	1.4e-44	38.8
WP_007060303.1\|2640005_2640668_-	CRISPR-associated protein Cas5	Q332K9	Clostridium_botulinum_C_phage	1.5e-42	41.4
WP_007060302.1\|2640703_2642365_-	acetolactate synthase large subunit	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	6.8e-44	25.5
WP_007060301.1\|2642761_2643757_-	TIM barrel protein	NA	NA	NA	NA
WP_007060300.1\|2644702_2645275_+	Uma2 family endonuclease	NA	NA	NA	NA
WP_007060299.1\|2645333_2648774_-	Ig-like domain-containing protein	A0A1D6Z291	Staphylococcus_phage	6.3e-28	46.7

DBSCAN-SWA_2

3236462 : 3246285

Enterobacteria_phage(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007060463.1\|3236462_3237293_-	YitT family protein	M1Q1P6	Streptococcus_phage	9.6e-31	28.6
WP_007060462.1\|3237624_3238593_-	LCP family protein	NA	NA	NA	NA
WP_007060461.1\|3238814_3239789_+	right-handed parallel beta-helix repeat-containing protein	A0A2H4PIX9	Corynebacterium_phage	1.3e-26	41.6
WP_007060460.1\|3239837_3240278_-	VanZ family protein	NA	NA	NA	NA
WP_007060459.1\|3240279_3241305_-	GDP-mannose 4,6-dehydratase	A0A2K9L4U8	Tupanvirus	7.2e-36	31.9
WP_007060458.1\|3241333_3242677_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	7.6e-86	41.0
WP_007060457.1\|3242745_3243291_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	1.3e-44	51.1
WP_007060456.1\|3243313_3244195_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	1.2e-36	37.1
WP_007060455.1\|3244294_3245191_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	3.2e-96	60.4
WP_007060454.1\|3245214_3246285_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	2.2e-75	44.0

DBSCAN-SWA_3

3701747 : 3752695

Clostridium_phage(28.0%)

tail,terminase,capsid,portal,integrase,plate

attL 3695770:3695786|attR 3712496:3712512

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3695770:3695786	attL	NA	NA	NA	NA
WP_048030171.1\|3701747_3702734_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_048030174.1\|3703132_3703699_-	lytic transglycosylase domain-containing protein	A0A0H3V0Q1	Geobacillus_virus	4.7e-13	39.7
WP_007060802.1\|3703700_3704336_-	dephospho-CoA kinase	NA	NA	NA	NA
WP_007060801.1\|3704367_3707010_-	DNA polymerase I	F8WQ35	Bacillus_phage	4.0e-62	33.4
WP_007060800.1\|3707212_3707542_-	YbjQ family protein	NA	NA	NA	NA
WP_007060799.1\|3707716_3707854_-	hypothetical protein	NA	NA	NA	NA
WP_007060798.1\|3708202_3709879_-	formate--tetrahydrofolate ligase	NA	NA	NA	NA
WP_007060797.1\|3710218_3711424_-	anaerobic nitric oxide reductase flavorubredoxin	NA	NA	NA	NA
WP_007060796.1\|3711512_3712211_-	iron-sulfur cluster repair di-iron protein	NA	NA	NA	NA
WP_007060795.1\|3712477_3713020_-	DNA topology modulation protein	A0A097BYE2	Leuconostoc_phage	1.0e-33	42.9
3712496:3712512	attR	NA	NA	NA	NA
WP_007060794.1\|3713063_3713822_-	DUF4085 family protein	NA	NA	NA	NA
WP_007060793.1\|3713818_3714442_-	aspartyl-phosphate phosphatase Spo0E family protein	NA	NA	NA	NA
WP_007060792.1\|3714864_3715866_-	GGGtGRT protein	NA	NA	NA	NA
WP_007060791.1\|3715887_3716580_-	nitrogen-fixing protein NifU	NA	NA	NA	NA
WP_007060790.1\|3716945_3718658_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	4.4e-06	63.0
WP_007060789.1\|3718704_3719700_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_156184586.1\|3720134_3720293_-	hypothetical protein	NA	NA	NA	NA
WP_048030176.1\|3720285_3722712_-	hypothetical protein	A0A2H4J056	uncultured_Caudovirales_phage	9.3e-151	39.8
WP_048030177.1\|3722722_3723103_-	hypothetical protein	NA	NA	NA	NA
WP_048030179.1\|3723120_3723555_-	hypothetical protein	NA	NA	NA	NA
WP_048030181.1\|3723869_3724070_-	hypothetical protein	NA	NA	NA	NA
WP_169823843.1\|3724226_3724385_-	hypothetical protein	NA	NA	NA	NA
WP_048030182.1\|3724503_3724704_-	helix-turn-helix transcriptional regulator	A0A2H4J765	uncultured_Caudovirales_phage	3.0e-07	42.4
WP_048030184.1\|3724753_3725101_-	hypothetical protein	NA	NA	NA	NA
WP_048030185.1\|3725266_3725848_-	hypothetical protein	NA	NA	NA	NA
WP_048030186.1\|3725870_3726923_-	hypothetical protein	A0A0A7HER1	Arthrobacter_phage	1.0e-08	31.4
WP_048030188.1\|3726934_3727183_-	hemolysin XhlA family protein	NA	NA	NA	NA
WP_048030190.1\|3727240_3727462_-	helix-turn-helix transcriptional regulator	A0A2K9V4D5	Faecalibacterium_phage	2.5e-15	54.9
WP_169823844.1\|3727582_3727723_-	hypothetical protein	NA	NA	NA	NA
WP_048030192.1\|3727738_3727918_-	hypothetical protein	NA	NA	NA	NA
WP_053075341.1\|3727917_3729561_-	hypothetical protein	H7BVN1	unidentified_phage	5.6e-83	38.5
WP_082141605.1\|3729598_3730657_-	group II intron reverse transcriptase domain-containing protein	H7BVN0	unidentified_phage	2.0e-89	51.0
WP_048030195.1\|3730936_3731278_-	diversity-generating retroelement protein Avd	A0A2K9VGX0	Faecalibacterium_phage	1.2e-24	50.0
WP_048030197.1\|3731366_3731678_-	hypothetical protein	NA	NA	NA	NA
WP_048030199.1\|3731694_3732093_-	hypothetical protein	NA	NA	NA	NA
WP_048030201.1\|3732107_3732944_-	YmfQ family protein	A0A2H4J1P4	uncultured_Caudovirales_phage	7.9e-17	38.1
WP_053075342.1\|3732936_3733995_-\|plate	baseplate J/gp47 family protein	A0A0A7RUN3	Clostridium_phage	1.2e-46	35.7
WP_048030203.1\|3733987_3734419_-	DUF2634 domain-containing protein	A0A0A8WJ32	Clostridium_phage	3.9e-20	44.7
WP_048030204.1\|3734415_3734733_-	DUF2577 domain-containing protein	NA	NA	NA	NA
WP_048030206.1\|3734734_3735742_-	hypothetical protein	A0A0A7RTP6	Clostridium_phage	4.5e-67	41.2
WP_053075343.1\|3735738_3736161_-	hypothetical protein	A0A2H4J045	uncultured_Caudovirales_phage	8.1e-10	31.4
WP_048030208.1\|3736173_3739611_-	transglycosylase SLT domain-containing protein	A0A1L2JY60	Aeribacillus_phage	1.1e-27	33.1
WP_048030210.1\|3739787_3740480_-	hypothetical protein	NA	NA	NA	NA
WP_169823845.1\|3740522_3740699_-	hypothetical protein	NA	NA	NA	NA
WP_048030212.1\|3740719_3741163_-	hypothetical protein	A0A0A7RTP2	Clostridium_phage	8.2e-13	32.8
WP_048030214.1\|3741182_3741620_-\|tail	phage tail tube protein	NA	NA	NA	NA
WP_048030216.1\|3741637_3742699_-\|tail	phage tail sheath subtilisin-like domain-containing protein	A0A0K2SUH8	Clostridium_phage	7.8e-78	47.5
WP_048030218.1\|3742716_3743151_-	hypothetical protein	NA	NA	NA	NA
WP_053075344.1\|3743153_3743705_-	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_048030221.1\|3743708_3744035_-	DUF3599 family protein	NA	NA	NA	NA
WP_048030223.1\|3744035_3744383_-	hypothetical protein	NA	NA	NA	NA
WP_048030225.1\|3744391_3744712_-	hypothetical protein	NA	NA	NA	NA
WP_048030227.1\|3744727_3745678_-\|capsid	P2 family phage major capsid protein	H7BVA6	unidentified_phage	7.6e-48	35.1
WP_048030229.1\|3745691_3746555_-	hypothetical protein	NA	NA	NA	NA
WP_048030231.1\|3746538_3747000_-	hypothetical protein	A0A1B1P7E4	Bacillus_phage	1.8e-10	32.1
WP_048030234.1\|3747032_3747350_-	hypothetical protein	NA	NA	NA	NA
WP_048030235.1\|3747350_3747689_-	hypothetical protein	NA	NA	NA	NA
WP_048030237.1\|3747750_3748008_-	hypothetical protein	NA	NA	NA	NA
WP_053075345.1\|3748029_3748971_-	hypothetical protein	A0A125RNU1	Streptomyces_phage	4.4e-16	42.7
WP_048030240.1\|3748963_3750505_-\|portal	phage portal protein	A0A1B1P7C8	Bacillus_phage	6.9e-99	41.7
WP_053075346.1\|3750501_3751914_-	DEAD/DEAH box helicase family protein	A0A1L6BXZ8	Clostridium_phage	5.9e-113	46.0
WP_048030243.1\|3751906_3752695_-\|terminase	terminase	A0A0A8WFS6	Clostridium_phage	9.4e-44	43.5

DBSCAN-SWA_4

5306159 : 5312020

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007062855.1\|5306159_5306639_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	4.1e-26	45.5
WP_007062854.1\|5306640_5307351_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A1D7SE76	Cyanophage	1.1e-43	43.7
WP_007062853.1\|5307398_5308838_+	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	2.3e-56	34.7
WP_007062852.1\|5308898_5309894_+	phosphoribosylformylglycinamidine cyclo-ligase	M4QRQ6	Synechococcus_phage	3.4e-67	45.0
WP_007062851.1\|5309881_5310493_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.3e-21	37.2
WP_007062850.1\|5310517_5312020_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	2.4e-64	44.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP011804

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CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP011803

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection