CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP007689	Listeria monocytogenes strain L2074 chromosome, complete genome	2 crisprs	DinG,cas3,DEDDh,RT,casR,WYL,csa3	0	8	6	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP007689_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007689_1

207759-207910

Unclear

Consensus_repeat	Method
CCGCCACCACCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGAGAC	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NZ_CP007689_1

>merge|NZ_CP007689|1|207759-207910|CRISPRCasFinder
CCGCCACCACCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGAGACACCGATGCTTCTCGGTTTTAATGCTCCTACTCCATCGGAACCGAGCTCATTCGAATTTCCGCCACCACCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGAGAC

>NZ_CP007689|1|1|207759-207910|CRISPRCasFinder
CCGCCACCACCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGAGAC	ACCGATGCTTCTCGGTTTTAATGCTCCTACTCCATCGGAACCGAGCTCATTCGAATTT
CCGCCACCACCTACGGATGAAGAGTTAAGACTTGCTTTGCCAGAGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007689.1\|WP_003722724.1\|195694_196903_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|182528
NZ_CP007689.1\|WP_009930499.1\|211229_211904_-\|DNA-alkylation-repair-protein	unknown	unknown	gnl\|CDD\|378033
NZ_CP007689.1\|WP_003722726.1\|198015_198324_+\|septation-regulator-SpoVG	unknown	unknown	gnl\|CDD\|237321
NZ_CP007689.1\|WP_003722727.1\|198710_200084_+\|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	unknown	unknown	gnl\|CDD\|184643
NZ_CP007689.1\|WP_003722742.1\|214619_215180_+\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|235457
NZ_CP007689.1\|WP_003722740.1\|213215_213839_+\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	unknown	unknown	gnl\|CDD\|235534
NZ_CP007689.1\|WP_003722729.1\|201133_201847_-\|listeriolysin-O-transcriptional-regulator-PrfA	unknown	unknown	gnl\|CDD\|223736
NZ_CP007689.1\|WP_003733966.1\|208919_209789_+\|phosphatidylcholine-phospholipase-C	unknown	unknown	gnl\|CDD\|214813
NZ_CP007689.1\|WP_003722735.1\|209860_210184_+\|DUF5502-family-protein	unknown	unknown	gnl\|CDD\|340321
NZ_CP007689.1\|WP_003722732.1\|205232_206765_+\|zinc-metalloproteinase-Mpl	unknown	unknown	gnl\|CDD\|225768
NZ_CP007689.1\|WP_003722728.1\|200134_201091_+\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_CP007689.1\|WP_031671561.1\|202117_203071_-\|phosphatidylinositol-specific-phospholipase-C	unknown	unknown	gnl\|CDD\|176497
NZ_CP007689.1\|WP_003725735.1\|210830_211163_-\|putative-heavy-metal-binding-protein	unknown	unknown	gnl\|CDD\|179228
NZ_CP007689.1\|WP_003722725.1\|197587_197896_+\|septation-regulator-SpoVG	unknown	unknown	gnl\|CDD\|237321
NZ_CP007689.1\|WP_047932352.1\|210318_210780_+\|YehR-family-lipoprotein	unknown	unknown	gnl\|CDD\|227145
NZ_CP007689.1\|WP_003722723.1\|195005_195698_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NZ_CP007689.1\|WP_003722739.1\|211980_212922_-\|L-lactate-dehydrogenase	unknown	unknown	gnl\|CDD\|178836
NZ_CP007689.1\|WP_031665609.1\|213928_214513_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
NZ_CP007689.1\|WP_047932349.1\|203312_204902_+\|cholesterol-dependent-cytolysin-listeriolysin-O	unknown	unknown	gnl\|CDD\|366559
NZ_CP007689.1\|WP_003722743.1\|215294_218834_+\|transcription-repair-coupling-factor	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|224118

Protein	Function_ID	Function_description	E-value
NZ_CP007689.1\|WP_003722724.1\|195694_196903_+\|ABC-transporter-permease	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	4.34799e-62
NZ_CP007689.1\|WP_009930499.1\|211229_211904_-\|DNA-alkylation-repair-protein	gnl\|CDD\|378033	pfam08713, DNA_alkylation, DNA alkylation repair enzyme. Proteins in this family are predicted to be DNA alkylation repair enzymes. The structure of a hypothetical protein in this family shows it to adopt a supercoiled alpha helical structure.	1.81561e-21
NZ_CP007689.1\|WP_003722726.1\|198015_198324_+\|septation-regulator-SpoVG	gnl\|CDD\|237321	PRK13259, PRK13259, septation regulator SpoVG.	5.03804e-54
NZ_CP007689.1\|WP_003722727.1\|198710_200084_+\|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	gnl\|CDD\|184643	PRK14354, glmU, bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU.	0
NZ_CP007689.1\|WP_003722742.1\|214619_215180_+\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	4.98809e-109
NZ_CP007689.1\|WP_003722740.1\|213215_213839_+\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	gnl\|CDD\|235534	PRK05618, PRK05618, 50S ribosomal protein L25/general stress protein Ctc; Reviewed.	2.38585e-63
NZ_CP007689.1\|WP_003722729.1\|201133_201847_-\|listeriolysin-O-transcriptional-regulator-PrfA	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	9.59942e-12
NZ_CP007689.1\|WP_003733966.1\|208919_209789_+\|phosphatidylcholine-phospholipase-C	gnl\|CDD\|214813	smart00770, Zn_dep_PLPC, Zinc dependent phospholipase C (alpha toxin). This domain conveys a zinc dependent phospholipase C activity (EC 3.1.4.3). It is found in a monomeric phospholipase C of Bacillus cereus as well as in the alpha toxin of Clostridium perfringens and Clostridium bifermentans, which is involved in haemolysis and cell rupture. It is also found in a lecithinase of Listeria monocytogenes, which is involved in breaking the 2-membrane vacuoles that surround the bacterium. Structure information: PDB 1ca1.	6.00128e-87
NZ_CP007689.1\|WP_003722735.1\|209860_210184_+\|DUF5502-family-protein	gnl\|CDD\|340321	pfam17606, DUF5502, Family of unknown function (DUF5502). This is a family of unknown function found in Listeria.	5.76244e-49
NZ_CP007689.1\|WP_003722732.1\|205232_206765_+\|zinc-metalloproteinase-Mpl	gnl\|CDD\|225768	COG3227, LasB, Zinc metalloprotease (elastase) [Amino acid transport and metabolism].	3.90486e-139
NZ_CP007689.1\|WP_003722728.1\|200134_201091_+\|ribose-phosphate-diphosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	0
NZ_CP007689.1\|WP_031671561.1\|202117_203071_-\|phosphatidylinositol-specific-phospholipase-C	gnl\|CDD\|176497	cd00137, PI-PLCc, Catalytic domain of prokaryotic and eukaryotic phosphoinositide-specific phospholipase C. This subfamily corresponds to the catalytic domain present in prokaryotic and eukaryotic phosphoinositide-specific phospholipase C (PI-PLC), which is a ubiquitous enzyme catalyzing the cleavage of the sn3-phosphodiester bond in the membrane phosphoinositides (phosphatidylinositol, PI; Phosphatidylinositol-4-phosphate, PIP; phosphatidylinositol 4,5-bisphosphate, PIP2) to yield inositol phosphates (inositol monosphosphate, InsP; inositol diphosphate, InsP2; inositol trisphosphate, InsP3) and diacylglycerol (DAG). The higher eukaryotic PI-PLCs (EC 3.1.4.11) have a multidomain organization that consists of a PLC catalytic core domain, and various regulatory domains. They play a critical role in most signal transduction pathways, controlling numerous cellular events, such as cell growth, proliferation, excitation and secretion. These PI-PLCs strictly require Ca2+ for their catalytic activity. They display a clear preference towards the hydrolysis of the more highly phosphorylated PI-analogues, PIP2 and PIP, to generate two important second messengers, InsP3 and DAG. InsP3 triggers inflow of calcium from intracellular stores, while DAG, together with calcium, activates protein kinase C, which then phosphorylates other molecules, leading to altered cellular activity. In contrast, bacterial PI-PLCs contain a single catalytic domain. Although their precise physiological function remains unclear, bacterial PI-PLCs may function as virulence factors in some pathogenic bacteria. They participate in Ca2+-independent PI metabolism. They are characterized as phosphatidylinositol-specific phospholipase C (EC 4.6.1.13) that selectively hydrolyze PI, not PIP or PIP2. The TIM-barrel type catalytic domain in bacterial PI-PLCs is very similar to the one in eukaryotic PI-PLCs, in which the catalytic domain is assembled from two highly conserved X- and Y-regions split by a divergent linker sequence. The catalytic mechanism of both prokaryotic and eukaryotic PI-PLCs is based on general base and acid catalysis utilizing two well conserved histidines, and consists of two steps, a phosphotransfer and a phosphodiesterase reaction. This superfamily also includes a distinctly different type of eukaryotic PLC, glycosylphosphatidylinositol-specific phospholipase C (GPI-PLC), an integral membrane protein characterized in the protozoan parasite Trypanosoma brucei. T. brucei GPI-PLC hydrolyzes the GPI-anchor on the variant specific glycoprotein (VSG), releasing dimyristyl glycerol (DMG), which may facilitate the evasion of the protozoan to the host#s immune system. It does not require Ca2+ for its activity and is more closely related to bacterial PI-PLCs, but not mammalian PI-PLCs.	1.7933e-113
NZ_CP007689.1\|WP_003725735.1\|210830_211163_-\|putative-heavy-metal-binding-protein	gnl\|CDD\|179228	PRK01119, PRK01119, putative heavy metal-binding protein.	8.98192e-61
NZ_CP007689.1\|WP_003722725.1\|197587_197896_+\|septation-regulator-SpoVG	gnl\|CDD\|237321	PRK13259, PRK13259, septation regulator SpoVG.	2.92652e-53
NZ_CP007689.1\|WP_047932352.1\|210318_210780_+\|YehR-family-lipoprotein	gnl\|CDD\|227145	COG4808, COG4808, Uncharacterized protein conserved in bacteria [Function unknown].	9.01418e-59
NZ_CP007689.1\|WP_003722723.1\|195005_195698_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	7.27113e-121
NZ_CP007689.1\|WP_003722739.1\|211980_212922_-\|L-lactate-dehydrogenase	gnl\|CDD\|178836	PRK00066, ldh, L-lactate dehydrogenase; Reviewed.	0
NZ_CP007689.1\|WP_031665609.1\|213928_214513_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	3.99359e-10
NZ_CP007689.1\|WP_047932349.1\|203312_204902_+\|cholesterol-dependent-cytolysin-listeriolysin-O	gnl\|CDD\|366559	pfam01289, Thiol_cytolysin, Thiol-activated cytolysin.	6.12523e-178
NZ_CP007689.1\|WP_003722743.1\|215294_218834_+\|transcription-repair-coupling-factor	gnl\|CDD\|224118	COG1197, Mfd, Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription].	0

>NZ_CP007689.1|WP_003722732.1|205232_206765_+|zinc-metalloproteinase-Mpl
MKSKLICIIMVIAFQAHFTMTVKADSVGEEKLQNNTQAKKTPADLKALPDSCEAKDFYKNFKILDMTKDKLGVTHYTLALSSGGYLTDNDEIKVHVTPDNKITFINGDLQQGQLRITNQIKITEKNAIEKAFEAIGQSEAHVKSYVGNPVKEKEIILNSRTKRLVYNIKLIFAEPEVASWIVQVDAETGAILKKQNMLSEVERADTHKDFQALGKGANRLLQRPLHVMKINDLFYLVDRTHKGLIRTFDLKHNTDTSFGKVVSNKTNMFTDPEFSSAVDAHFYASEVYEYYKNVHQLESLDGKGGEIDSFVHYGLNCNNAFWDGQEILYGDGDKKNFKPFSCAKTIVGHELTHAVIQYSAGLEYEGQSGALNESFADVFGYFIAPNHWLIGEDVCVRGSRDGRIRSIKDPDKYNQAAHMKDYESLPITEEGDWGGVHYNSGIPNKAAYNTITKLGKEKTEQLYFRALKYYLTKKSQFTDAKKALQQAAKDLYGEDASKKVAEAWEAVGVN
>NZ_CP007689.1|WP_047932349.1|203312_204902_+|cholesterol-dependent-cytolysin-listeriolysin-O
MKKIMLVFITLILVSLPIAQQTEAKDASAFNKENSISSMAPPASPPASPKTPIEKKHADEIDKYIQGLDYNKNNVLVYHGDAVTNVPPRKGYKDGNEYIVVEKKKKSINQNNADIQVVNAISSLTYPGALVKANSELVENQPDVLPVKRDSLTLSIDLPGMTNQDNKIVVKNATKSNVNNAVNTLVERWNEKYAQAYPNVSAKIDYDDEMAYSESQLIAKFGTAFKAVNNSLNVNFGAISEGKMQEEVISFKQIYYNVNVNEPTRPSRFFGKAVTKEQLQALGVNAENPPAYISSVAYGRQVYLKLSTNSHSTKVKAAFDAAVSGKSVSGDVELTNIIKNSSFKAVIYGGSAKDEVQIIDGNLGDLRDILKKGATFNRETPGVPVAYTTNFLKDNELAVIKNNSEYIETTSKAYTDGKINIDHSGGYVAQFNISWDEVNYDPEGNEIVQHKNWSENNKSKLAHFTSSIYLPGNARNINVYAKECTGLAWEWWRTVIDDRNLPLVKNRNISIWGTTLYPKYSNKVDNPIE
>NZ_CP007689.1|WP_031671561.1|202117_203071_-|phosphatidylinositol-specific-phospholipase-C
MYKNYLQRTLVLLLCFILYFFTFPLGGKAYSLNNWNKPIKNSVTTKQWMSALPDTTSLAALSIPGTHDTMSYNGDITWTLTKPLAQTQTMSLYQQLEAGIRYIDIRAKDNLNIYHGPIFLNASLSGVLETITQFLKKNPKETIIMRLKDEQNSNDSFDYRIQPLINIYKDYFYTTPRTDTSNKIPTLKDVRGKIFLLSENHTKKPLVINSRKFGMQFGAPNQVIQDDYNGPSVKTKFKEIVQTAYQASKADNKLFLNHISATSLTFTPRQYAAALNNKVEQFVLNLTSEKVRGLGILIMDFPEKQTIKNIIKNNKFN
>NZ_CP007689.1|WP_003722729.1|201133_201847_-|listeriolysin-O-transcriptional-regulator-PrfA
MNAQAEEFKKYLETNGIKPKQFHKKELIFNQWDPQEYCIFLYDGITKLTSISENGTIMNLQYYKGAFVIMSGFIDTETSVGYYNLEVISEQATAYVIKINELKELLSKNLTHFFYVFQTLQKQVSYSLAKFNDFSINGKLGSICGQLLILTYVYGKETPDGIKITLDNLTMQELGYSSGIAHSSAVSRIISKLKQEKVIVYKNSCFYVQNLDYLKRYAPKLDEWFYLACPATWGKLN
>NZ_CP007689.1|WP_003722728.1|200134_201091_+|ribose-phosphate-diphosphokinase
MSNEYFDPKLKIFSLNSNRELAEEIAKEVGIELGKSSVTHFSDGEIQINIEESIRGCHVYVIQSTSNPVNQNLMELLIMIDALKRASAATINIVMPYYGYARQDRKARSREPITAKLVANLIETAGATRMITLDMHAPQIQGFFDIPIDHLNAVRLLSDYFSERHLGDDLVVVSPDHGGVTRARKMADRLKAPIAIIDKRRPRPNVAEVMNIVGNVEGKVCIIIDDIIDTAGTITLAAKALREAGATKVYACCSHPVLSGPAMKRIEESPIEKLVVTNSIALPEEKWIDKMEQLSVAALLGEAIVRVHENASVSSLFE
>NZ_CP007689.1|WP_003722727.1|198710_200084_+|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU
MSKRYAVVLAAGQGTRMKSKLYKVLHPVCGKPMVEHVVDQISTLNVDKVVTIVGHGAEKVQEHLAGKSEFVKQDEQLGTAHAVLQAKAELAGKDGVTLVVCGDTPLIEASTMEALLKYHHEKRAKATILTTVIEDPTGYGRIIRDDLGIVEKIVEHKDATEKEQRISEINTGTYCFDNKALFEALENVSNDNVQGEYYLPDVIKILKDSDEVVAAYRMESFEESLGVNDRIALAEASKLMQRRINENHMRNGVTLVNPESTYIDIDVKIGQDTVIEPGVMLRGKTVIGDDCVVTSGSEIVNSVIGERVHVRTSSIFESKVGDDVQIGPYAHLRPESDIHDHVKIGNYVETKKAVVGEGTKLPHFIYMGDAEIGKNVNVGCGSIAVNYDGKNKAKTIIGDNVFVGCNSNLIAPVKVGDRAFIAAGSTITKDVPEDALGIARAKQDNKLGYAKHLNHGK
>NZ_CP007689.1|WP_003722726.1|198015_198324_+|septation-regulator-SpoVG
MQVTDVRLRRVETDGRMRAIASITLDEEFVVHDIRVIDGNNGLFVAMPSKRGVDGEFRDIAHPINSDTRAKIQEVVLAEYERVGEEEATAVTEEESESVSAE
>NZ_CP007689.1|WP_003722725.1|197587_197896_+|septation-regulator-SpoVG
MEITDVRLRRVETDGRMKAISSITIDGEFVIHDIRVIDGNEGLFVAMPSKRTPDGEFRDIAHPINSGTRAKIQEAVLAAYEVADEPAVNEESSADESIVEEN
>NZ_CP007689.1|WP_003722724.1|195694_196903_+|ABC-transporter-permease
MNVLQSMKMAWKQLKASKLRSFLTMLGIIIGVASVILLVSLGNGVTQEVDDQMGDLGSNLITVVNSSVNPNDKYTYDEVMKYQNIDGVKSVSPELSGQVNATFDYKSSSNKVIGTNDQYKAARSLEMKEGRFLLPIDTEYGQKVAVIGSTVASDLFGFGDPIGETIRLNGMPYKVVGVLKEKGASMMGSSDDQIFIPISSAQRLLKDTNVRTIYVETKSAEDVDFVVNTLESRLAIKFGDEKEQEKNASSAQMGPSYQVINQQEILNAFNTISTTLTTALGAIAAISLVVGGIGIMNIMLVSVSERTREIGIRKALGAKKRAILLQFLIESIVISVCGGVIGIIIGVSGALIFGSVAGISSGITAGTIIFSFVFSLCIGVIFGIAPANKASKLRPIDALRSE
>NZ_CP007689.1|WP_003722723.1|195005_195698_+|ABC-transporter-ATP-binding-protein
MPKPLIDMKNLTKTYTLGGETFKALDDVTFTVEQGEFLSIVGPSGSGKSTLMNMIGCLDVPDEGSYHLDDVDVFKLSDNKLSEIRNKKIGFIFQQFNLLPKLSAFENVELPLIYAGLSVSAREKAAIECLEKVGLLEKRRNLPTQLSGGQQQRVAIARALAGKPQILLADEPTGALDSKTGKEVMGILQELNRAGNTIVMITHDPTIASYGTRSIRIQDGKLFHEEATQA
>NZ_CP007689.1|WP_003733966.1|208919_209789_+|phosphatidylcholine-phospholipase-C
MKFKKVVLGMCLTASVLVFPVTIKANACCDEYLQTPAAPHDIDSKLPHKLSWSADNPTNTDVNTHYWLFKQAEKILAKDVNHMRANLMNELKKFDKQIAQGIYDADHKNPYYDTSTFLSHFYNPDRDNTYLPGFANAKITGAKYFNQSVTDYREGKFDTAFYKLGLAIHYYTDISQPMHANNFTAISYPPGYHCAYENYVDTIKHNYQATEDMVAKRFCSDDVKDWLYENAKRAKADYPKIVNAKTKKSYLVGNSEWKKDTVEPTGARLRDSQQTLAGFLEFWSKKTNE
>NZ_CP007689.1|WP_003722735.1|209860_210184_+|DUF5502-family-protein
MYIKGRLIFFFVMFVIALCSVLILLIIKISVWKDEPFHLSDAKEIECLGSCEIKNTNQKIHFFSIKENLFEEKGDIAGILNEDEQKVADKSIFIVILDDEKGIANEE
>NZ_CP007689.1|WP_047932352.1|210318_210780_+|YehR-family-lipoprotein
MKMLKKGTAVLFVMIMAVMLVACGDKEETKTYTLSRNGVDSKLTYTYKGDKVTKQTAENTMSYASLGVASKEDAEKMLKATSDKFQGIDGLKEKIEYKDDKAIETLEVDYTKISSEDMNKIPGMSSNGDTSKGISMEESAKMLESQGYKEVSK
>NZ_CP007689.1|WP_003725735.1|210830_211163_-|putative-heavy-metal-binding-protein
MIVTTSPNIEGKQIIEYKKIVFGEVITGVNFMKDIGAGLRNFFGGRSQGYEDELINAREEAIREMEQRAKDIGANAVIGVDIDYEVLGADNGMLMVTASGTAVVIEAQDY
>NZ_CP007689.1|WP_009930499.1|211229_211904_-|DNA-alkylation-repair-protein
MITFDQLDTELQALENPNTIKIFRNHGCPDSLDLYGLKIGDLKKIIRREKLTKNHELAVKLIESNNSDLIYLGLLAINPNKITTEQIEKWNIAFRETWSQLTFGLASIVSKRDDALLFAKTWIESDYDLTKSMGWQIYSEHINNLPEAETLLQRAKETLQTETNRTRYSMNGFIITCGIYKDDLHEKAMEAAKSVGKVHVNLGNTACKVPDAISYIEKARNRTK
>NZ_CP007689.1|WP_003722739.1|211980_212922_-|L-lactate-dehydrogenase
MKDHQKIILVGDGAVGSSYAFACVNLSIGQEFGIIDIDKDRTIGDAMDLSHAVPFSTPKKIYSANYSDCHDADLVVVTAGTAQKPGETRLDLVNRNIKIMKGIVDEVMASGFDGIFLIASNPVDILTYATWKFSGLPKERVIGSGTSLDTARFRMSIADYLKVDARNVHGYILGEHGDTEFPAWSHTTVGGLPITEWISEDEQGAMDTIFVSVRDAAYEIINKKGATFYGVAAALARITKAILNNENAILPLSVYLDGHYGMNDIYIGAPAVVNRQGVRHIVEMNLNDKEKEQMKNSADTLKKVLDDAMKQID
>NZ_CP007689.1|WP_003722740.1|213215_213839_+|50S-ribosomal-protein-L25/general-stress-protein-Ctc
MATTLEVQKRETTQHSEVTRLRSEGKVPGIIYGYKSENVPVSVDSLELIKAVRDNGRNAVFSVTVDGKKLNVLLHEYQVDPLKDVLVHVDLLAVDMNEEVETDVRVVLVGDAPGVKAGGVLQQIIHDVKVSATPEKLPETIELDISSLEIGDVLTTNDLPENKDYVVQAEEEETVVTVSAPRAEEEPTTTEAPEPEAVHGKDEEPVE
>NZ_CP007689.1|WP_031665609.1|213928_214513_+|GNAT-family-N-acetyltransferase
MLDKSVPHISVIMVNHDATNYPEFHLPAGYSFCFYKDGLEEDWCRLQLETGQVLSMDSIRARFETEFGNEKEKLTKHCIFVKAPNGEIIGTAMLWDGNTFGKMESRIHWVAVLDSHGGKGIAKALLSKILGLNKSKFVYLTTQTGSYQAIYLYRKFGFEKYVGKTPENWKTVNFQEEKETAWQIIENKIAEHQA
>NZ_CP007689.1|WP_003722742.1|214619_215180_+|aminoacyl-tRNA-hydrolase
MKLIAGLGNPGKKYERTRHNVGFMVVDELSFRHQTPWKKSKFNGMTSEIIVGGEKMILVKPLTFMNASGECIRPLMDYYNIPIEDVVIVYDDLDLPVGKIRLRQKGSAGGHNGMKSIIQHVKTQEFNRIRVGVSRPLKGEVINYVLGDFPKAEQPDIIAAIQKSADAIEDFAQTPFIEVMNKYNQK
>NZ_CP007689.1|WP_003722743.1|215294_218834_+|transcription-repair-coupling-factor
MKGLQQLIYEQKDIRAVLNALDEKEKAQLVTGLTGSSRALFASVVEGASKRPVVFVTHNLYHAQKLYDDLLSLMDVDRLFLYPADELISSELSISSPELRGQRVEALDFLLSGKPGIVIVPVAGLRKMLPPVSLWKHFNISIVEGEEIDPDVLRQKLVTMGYTMSGMVNTPGEFSVRGGIIDIYPITEEFPIRIELFDTEVDSLRFFDVETQRSTTRVEEFRLLPATEIILDQSYYPDIVKRLEKKMMLTLNELKEQEDKQALIENLEEDLEMLRSGVKPDMFFKYIGLAYPDPASLFDYLPKNTAILLDEFGRILETEESLEREEAEWQTETLSRMETVRDVQVSHSFKKLLEGNHSPKIYLSLFQKQMASMRVSKTTNIVYKQMQQFHGQMNVLKTELESWHKNNYAVVILAPNLERAEKMQQTLTDYDMESTILKKESDVPKYGMVQFVIGTFQNGFELPLAKVAIISETELFNKKIKKVKKRQKLSNAERIQSYSELKVGDYVVHVNHGIARYVGMETLDINGVHKDYLLLVYQGEDKLFIPVDQLDLVQKYVGAEGKSPRLNKLGGAEWKRVKKKVQASVQDIADDLIKLYAEREAEKGYAFSADDEMQREFEEAFPYQETEDQLRSISEIKKDMERPRPMDRLLVGDVGYGKTEVALRAAFKAIMDGKQVAFLVPTTILAQQHFETMKERFQGFPIEIGLLSRFRTKKQQTETLKGMKNGTVDVVVGTHRLLSKDVEYQDLGLLIVDEEQRFGVTHKEKIKQMRSKIDVLTLTATPIPRTLHMSMLGVRDLSVIETPPANRFPVQTYVAEQNNVLVREAIERELARDGQVYYLYNRVESITQKADEISAMVPDARVATAHGQMGESELESVILSFLEGEFDVLVTTTIIETGVDIPNVNTLFVQDADRMGLSQLYQLRGRVGRWNRIAYAYFMYQKDKILREEAEKRLSAIKEFTELGSGFKIAMRDLSIRGAGNILGAQQHGFIDSVGFDLYSQMLKEAIEAKKPKEEQKQIVPVEIDIQADAYIPEYYITDGRQKIEMYKRFRNIETLSELEDLQSDMIDRFGEYPEEVEYLFTMTELKVHALEVGIESVKQEQNKITMLFSESGTAGIRGDIVMQIIGEFGRMVGVGMEGTQLKITINVQNKPLKEWLYQVKSLAEKLRGAMKEKASTEN

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Crispr_ID: NZ_CP007689_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007689_2

1415876-1416224

Orphan

I-A

Consensus_repeat	Method
ATTTACATTTCACAATAAGTAACTAAAA	PILER-CR
ATTTACATTTCACAATAAGTAACTAAAA	CRISPRCasFinder
ATTTACATTTCACAATAAGTAACTAAAAC	CRT

5 spacers

The CRISPR arrays of NZ_CP007689_2

>merge|NZ_CP007689|2|1415876-1416224|PILER-CR,CRISPRCasFinder,CRT
ATTTACATTTCACAATAAGTAACTAAAACGAAATTGTAAAATCTATATCCGTTGATTCAACAAAATTTACATTTCACAATAAGTAACTAAAACTTAATTTGATAGTCATAATTTATTTCCTCCTATTTTATTTACATTTCACAATAAGTAACTAAAATATAGAAAGGAGTTGATACAGTGAAGGATGTTTTAGATTTACATTTCACAATAAGTAACTAAAACTTATAAACGACATTTTAGAAGCAGGAGTAGAAAAATTTACATTTCACAATAAGTAACTAAAACTTGTAACCCATCGCTGTCCCTTTGACAAAAATCGCATTTACATTTCACAATAAGTAACTAAAAC

>NZ_CP007689|2|1|1415876-1416223|PILER-CR
ATTTACATTTCACAATAAGTAACTAAAA	CGAAATTGTAAAATCTATATCCGTTGATTCAACAAA
ATTTACATTTCACAATAAGTAACTAAAA	CTTAATTTGATAGTCATAATTTATTTCCTCCTATTTT
ATTTACATTTCACAATAAGTAACTAAAA	TATAGAAAGGAGTTGATACAGTGAAGGATGTTTTAG
ATTTACATTTCACAATAAGTAACTAAAA	CTTATAAACGACATTTTAGAAGCAGGAGTAGAAAA
ATTTACATTTCACAATAAGTAACTAAAA	CTTGTAACCCATCGCTGTCCCTTTGACAAAAATCGC
ATTTACATTTCACAATAAGTAACTAAAA

>NZ_CP007689|2|2|1415876-1416223|CRISPRCasFinder
ATTTACATTTCACAATAAGTAACTAAAA	CGAAATTGTAAAATCTATATCCGTTGATTCAACAAA
ATTTACATTTCACAATAAGTAACTAAAA	CTTAATTTGATAGTCATAATTTATTTCCTCCTATTTT
ATTTACATTTCACAATAAGTAACTAAAA	TATAGAAAGGAGTTGATACAGTGAAGGATGTTTTAG
ATTTACATTTCACAATAAGTAACTAAAA	CTTATAAACGACATTTTAGAAGCAGGAGTAGAAAA
ATTTACATTTCACAATAAGTAACTAAAA	CTTGTAACCCATCGCTGTCCCTTTGACAAAAATCGC
ATTTACATTTCACAATAAGTAACTAAAA

>NZ_CP007689|2|1|1415876-1416224|CRT
ATTTACATTTCACAATAAGTAACTAAAAC	GAAATTGTAAAATCTATATCCGTTGATTCAACAAA
ATTTACATTTCACAATAAGTAACTAAAAC	TTAATTTGATAGTCATAATTTATTTCCTCCTATTTT
ATTTACATTTCACAATAAGTAACTAAAAT	ATAGAAAGGAGTTGATACAGTGAAGGATGTTTTAG
ATTTACATTTCACAATAAGTAACTAAAAC	TTATAAACGACATTTTAGAAGCAGGAGTAGAAAA
ATTTACATTTCACAATAAGTAACTAAAAC	TTGTAACCCATCGCTGTCCCTTTGACAAAAATCGC
ATTTACATTTCACAATAAGTAACTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007689.1\|WP_003721297.1\|1414118_1414799_-\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|153212
NZ_CP007689.1\|WP_031668100.1\|1411052_1412888_-\|lmo0514-family-class-1-internalin	unknown	unknown	gnl\|CDD\|380190
NZ_CP007689.1\|WP_003733191.1\|1421250_1421718_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|238129
NZ_CP007689.1\|WP_012951252.1\|1407458_1407827_+\|DUF1304-domain-containing-protein	unknown	unknown	gnl\|CDD\|226282
NZ_CP007689.1\|WP_049949165.1\|1410520_1410952_-\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP007689.1\|WP_009932856.1\|1413269_1413728_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378956
NZ_CP007689.1\|WP_003727301.1\|1418822_1419116_-\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99908
NZ_CP007689.1\|WP_003721290.1\|1420835_1421234_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007689.1\|WP_012951247.1\|1414905_1415484_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007689.1\|WP_003733192.1\|1421745_1422348_-\|SIS-domain-containing-protein	unknown	unknown	gnl\|CDD\|223865
NZ_CP007689.1\|WP_026749759.1\|1405896_1407312_-\|multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP007689.1\|WP_003721303.1\|1408107_1408923_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NZ_CP007689.1\|WP_031665228.1\|1409043_1410474_+\|CapA-family-protein	unknown	unknown	gnl\|CDD\|225399
NZ_CP007689.1\|WP_047932806.1\|1424520_1425171_-\|transaldolase	unknown	unknown	gnl\|CDD\|223254
NZ_CP007689.1\|WP_012951245.1\|1420174_1420825_-\|ribulose-phosphate-3-epimerase	unknown	unknown	gnl\|CDD\|223114
NZ_CP007689.1\|WP_003721295.1\|1416461_1417397_-\|ribose-phosphate-pyrophosphokinase	unknown	unknown	gnl\|CDD\|234929
NZ_CP007689.1\|WP_003721294.1\|1417536_1418808_-\|PTS-galactitol-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226298
NZ_CP007689.1\|WP_014601718.1\|1413734_1414094_+\|Lin0512-family-protein	unknown	unknown	gnl\|CDD\|131113
NZ_CP007689.1\|WP_003733193.1\|1422351_1424412_-\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP007689.1\|WP_009930756.1\|1419131_1420178_-\|galactitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|176198

Protein	Function_ID	Function_description	E-value
NZ_CP007689.1\|WP_003721297.1\|1414118_1414799_-\|type-1-glutamine-amidotransferase	gnl\|CDD\|153212	cd01741, GATase1_1, Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. This group contains a subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. GATase activity catalyses the transfer of ammonia from the amide side chain of glutamine to an acceptor substrate. Glutamine amidotransferases (GATase) includes the triad family of amidotransferases which have a conserved Cys-His-Glu catalytic triad in the glutaminase active site. In this subgroup this triad is conserved. GATase activity can be found in a range of biosynthetic enzymes, including: glutamine amidotransferase, formylglycinamide ribonucleotide, GMP synthetase , anthranilate synthase component II, glutamine-dependent carbamoyl phosphate synthase, cytidine triphosphate synthetase, gamma-glutamyl hydrolase, imidazole glycerol phosphate synthase and, cobyric acid synthase. Glutamine amidotransferase (GATase) domains can occur either as single polypeptides, as in glutamine amidotransferases, or as domains in a much larger multifunctional synthase protein, such as CPSase.	7.71833e-60
NZ_CP007689.1\|WP_031668100.1\|1411052_1412888_-\|lmo0514-family-class-1-internalin	gnl\|CDD\|380190	NF033186, internalin_K, class 1 internalin InlK. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface-anchored proteins with an N-terminal signal peptide, leucine-rich repeats, and a C-terminal LPXTG processing and cell surface anchoring site. Members of this family are internalin K (InlK), a virulence factor. See articles PMID:17764999. for a general discussion of internalins, and PMID:21829365, PMID:22082958, and PMID:23958637 for more information about internalin K.	8.29186e-120
NZ_CP007689.1\|WP_012951252.1\|1407458_1407827_+\|DUF1304-domain-containing-protein	gnl\|CDD\|226282	COG3759, COG3759, Predicted membrane protein [Function unknown].	8.73125e-42
NZ_CP007689.1\|WP_049949165.1\|1410520_1410952_-\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	3.85905e-26
NZ_CP007689.1\|WP_014601718.1\|1413734_1414094_+\|Lin0512-family-protein	gnl\|CDD\|131113	TIGR02058, lin0512_fam, conserved hypothetical protein. This family consists of few members, broadly distributed. It occurs so far in several Firmicutes (twice in Oceanobacillus), one Cyanobacterium, one alpha Proteobacterium, and (with a long prefix) in plants. The function is unknown. The alignment includes a perfectly conserved motif GxGxDxHG near the N-terminus. [Hypothetical proteins, Conserved].	4.36834e-66
NZ_CP007689.1\|WP_003727301.1\|1418822_1419116_-\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|99908	cd05566, PTS_IIB_galactitol, PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain that are expressed on three distinct polypeptide chains, in contrast to other PTS sugar transporters. The three genes encoding these subunits (gatA, gatB, and gatC) comprise the gatCBA operon. Galactitol PTS permease takes up exogenous galactitol, releasing the phosphate ester into the cytoplasm in preparation for oxidation and further metabolism via a modified glycolytic pathway called the tagatose-6-phosphate glycolytic pathway. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include galactitol, chitobiose/lichenan, ascorbate, lactose, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	3.39912e-27
NZ_CP007689.1\|WP_003733191.1\|1421250_1421718_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	2.76446e-37
NZ_CP007689.1\|WP_003733192.1\|1421745_1422348_-\|SIS-domain-containing-protein	gnl\|CDD\|223865	COG0794, GutQ, Predicted sugar phosphate isomerase involved in capsule formation [Cell envelope biogenesis, outer membrane].	1.15952e-75
NZ_CP007689.1\|WP_026749759.1\|1405896_1407312_-\|multidrug-efflux-MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.81243e-80
NZ_CP007689.1\|WP_003721303.1\|1408107_1408923_+\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	5.01016e-50
NZ_CP007689.1\|WP_031665228.1\|1409043_1410474_+\|CapA-family-protein	gnl\|CDD\|225399	COG2843, PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) [Cell envelope biogenesis, outer membrane].	6.70557e-100
NZ_CP007689.1\|WP_047932806.1\|1424520_1425171_-\|transaldolase	gnl\|CDD\|223254	COG0176, MipB, Transaldolase [Carbohydrate transport and metabolism].	1.03831e-62
NZ_CP007689.1\|WP_012951245.1\|1420174_1420825_-\|ribulose-phosphate-3-epimerase	gnl\|CDD\|223114	COG0036, Rpe, Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism].	8.25352e-108
NZ_CP007689.1\|WP_003721295.1\|1416461_1417397_-\|ribose-phosphate-pyrophosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	2.38027e-153
NZ_CP007689.1\|WP_003721294.1\|1417536_1418808_-\|PTS-galactitol-transporter-subunit-IIC	gnl\|CDD\|226298	COG3775, GatC, Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism].	7.01085e-178
NZ_CP007689.1\|WP_009932856.1\|1413269_1413728_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|378956	pfam12802, MarR_2, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.	9.15558e-13
NZ_CP007689.1\|WP_003733193.1\|1422351_1424412_-\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	3.95572e-80
NZ_CP007689.1\|WP_009930756.1\|1419131_1420178_-\|galactitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|176198	cd08236, sugar_DH, NAD(P)-dependent sugar dehydrogenases. This group contains proteins identified as sorbitol dehydrogenases and other sugar dehydrogenases of the medium-chain dehydrogenase/reductase family (MDR), which includes zinc-dependent alcohol dehydrogenase and related proteins. Sorbitol and aldose reductase are NAD(+) binding proteins of the polyol pathway, which interconverts glucose and fructose. Sorbitol dehydrogenase is tetrameric and has a single catalytic zinc per subunit. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Related proteins include threonine dehydrogenase, formaldehyde dehydrogenase, and butanediol dehydrogenase. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Horse liver alcohol dehydrogenase is a dimeric enzyme and each subunit has two domains. The NAD binding domain is in a Rossmann fold and the catalytic domain contains a zinc ion to which substrates bind. There is a cleft between the domains that closes upon formation of the ternary complex.	0

>NZ_CP007689.1|WP_012951247.1|1414905_1415484_-|hypothetical-protein
MKKILVPILLLATILASCSSPNEKITKDTKISKTNTIRADYKVPKDIKELEDDSANIVKVKFLQNKTIGKDGSTISEIEILTSYKGNLEKGSKVDISEPWYLSDGKYVAVENYIALDKEQEYTIFLGEKDKDTYPLSSLGYGKFGGSLKEDQAVLADFNILGEVQKFDFISENTEEVKNYQLIKEQVAGKYK
>NZ_CP007689.1|WP_003721297.1|1414118_1414799_-|type-1-glutamine-amidotransferase
MIIDVLQHVPHEGPGLIANWARENQHQLKIHSLFEENAHVPNDSDFLIVLGGPMGINDTAEFPWLKDERKLIKRLSEQHKPVFGVCLGAQQIAATFGSEITVNKEKEVGWFPVKRTSDKLLFFPESLNVFHWHQDTFALPTGSTRLFASEGCLNQAFLYGENIIGLQFHFEMEKAGIETILRIDEAFITPGKYVQSVEVMREKDVPEDNKQMLEAILDYLINPKTI
>NZ_CP007689.1|WP_014601718.1|1413734_1414094_+|Lin0512-family-protein
MEQILFIQTGFGVDVHGQNITNAAERAVRNAIFTNSMPGIQGLLPDGDLQNMVVNIKLALPCDADQLDEDTIRAIIPYGTVTIEKMAGGMMTTSGIFLEDKEDKNDLMYIVNASVETGY
>NZ_CP007689.1|WP_009932856.1|1413269_1413728_+|MarR-family-transcriptional-regulator
MNNEQNMNQQIALFYFGYKAFTETADLIIAKHSLKRLHHRILFFTARMPGLTINELLTFLEISKQALHQPLAELKERELLTIEQGRRDKRQRCIFLTSAGKELENELGAAQRKQMSEIFTNSADTDGMHFTEVMEGYAKNRPGAAFIKDFKE
>NZ_CP007689.1|WP_031668100.1|1411052_1412888_-|lmo0514-family-class-1-internalin
MKKALKLFLAMICMFIMIYPSTAAHAEETNIVNIPDANLKTYLNGLLKQASDAPITKTQMNTIQTVTLSGSTYTDLTGLEEAGNLVTLSINNTNIQTLEPIKNQTSLTYLTVGGDNVKDSLFVDLNGLVNLQSLSINGSEVTHNVFKTFNKLPKLTYLYAQNSMKITDISALASLPALTTLFLQFDGIDDFRPLNDFESFKNGNLKALAAFGQNTGRTNPRITLKSGKLDYNETNQTLYLPFSMMPKPLTSFDGTVAPFSKSTSASNTYLGFNDVALPSARLSITEDGITVSGVTKEEFDNLDEIEYNARYDFPTGSYPTPPSMTSYTISSGTYDQYFDISHTLDLTADESFDYNQYDTTSEEQFLKDVHAETDDGTAVKSDFDQVVKLDVPGEYTVTLNAENAAGLKATPVTVKVTVHEKPVITSDSQISYKKETTKSVDEFLKEIHGSVTGNAVLTSDFDKVVDLNTPGEYTVTLNAINDRGQKADPVTVVVTVTTSDSGHVNPVPPTPEVKPTPQEETDQTIIPEPQSETTEDSVKEDQAKDGQAKSEEKADKTSLTTKENKVEKSEKTNQPKTKALPQTGDTNKTALPIAGVMLSLAALLIFRKSKS
>NZ_CP007689.1|WP_049949165.1|1410520_1410952_-|universal-stress-protein
MEKYHRILVAVDGSEPAKLAFEKGLELALKLDGVLGIASIVDLRAFSPNVSYDGSLEEKAELELKTSVNEYAEKARTAGVKQVETFVAKGNPKILLSTDIPAEFQAELIICGATGMNRVEKLVLGSVSSYIMAHAICDTLIAR
>NZ_CP007689.1|WP_031665228.1|1409043_1410474_+|CapA-family-protein
MKKLTYVIITGLVLVFIAGAFWITNSTNQSDQKATQTEPLKKTSPANVKTISSEAKKTLNSLASSGADKASISDLKQLIKELKSYPTEKNDSGVYLQNLTACLEAVKSYTTGKTDEKTLGKVYPAFLASEQKLSAIEKTNQYDWFYAAAATNQQGLKEKGVVTLTMVGDNSFGTYPETPEHLKFDNVFQKNNGNNTYVYKNCLPWFKSDDYTVINAESAFTNATKAENKKWRIKSDPAHVAFLPASGVEAANLANNHTMDYFQVGYDDTLKAFKENNIPVFNTDAPLETTIKGMKTVLLGYDCRMSQQSPAYLERIVKDVKKYKKEDTLVIVNMHWGVEYRETPTDYQTQFGHAILDAGADIIMGSHPHRLESVEKYKDKYIVYSMGDFAFGADPTLLSRMTSMFQLRFTKEDNKIVLKDISIVPTYENSDGSTTENNYQPLPVFGDDAKKIVDELNRISKPIEGGVTEYTYFDPF
>NZ_CP007689.1|WP_003721303.1|1408107_1408923_+|histidine-phosphatase-family-protein
MKKNIFKLLMALCAVLLIAGCGNSTSADKKETKETKEDGTVTFYVVRHGKTMLNTTDRVQGWSDAVLTPAGEEVVKSAGKGLKDVDFSAAYSSDSGRAIQTANLILKESDKSADKEVQTDPRFREFNFGSYEGDLNENMWTDIAKSQGKTLEEWQKAGLSPKDFANSVAALDKTRVKEGENWPAEDYATIQARLKEGLTDVAKKESKNGDSNVLLVSHGLSIGALLDTIEPGYKLPAEGIKNASVTKITYKDGKFTIGDVNDLSYVEKGSK
>NZ_CP007689.1|WP_012951252.1|1407458_1407827_+|DUF1304-domain-containing-protein
MAILAFILTFIVMIEHIYIMILEMFFANTKLAAKTFGVEKELLANKKVQTLFANQGLYNGFLAAGLVWGLFFAGAGMAETVQIFFLSCVVVAALFGGATSSKGILVKQGLPAVLALVAVLLV
>NZ_CP007689.1|WP_026749759.1|1405896_1407312_-|multidrug-efflux-MFS-transporter
MQQEATGGQKIRPIPIIASFLMAGFIGLFSETALNMALSDLIQVFDISSATVQWLTTGYLLTLGILVPISGLLLQWFTTRGLFFTAVSFSIAGTLIAALSPTFAMLMIGRVVQAVGTALLLPLMFNTILLIFPEHKRGSAMGMIGLVIMFAPAVGPTISGLILENLTWNWIFWISLPFLIIALLFGMKFMQNVSVVTKPKIDILSIILSTLGFGGVVFAFSSAGESGWGSATVLVSIIVGGLALGFFVWRQLTMEKPLMDLKVFKYPMFTLGLILVFISFMMILSTMILLPLYLQNSLALAAFSAGLVLLPGGVLNGLMSPFTGRLFDAYGPRALVIPGFIVAVVALFFLTRIEVGTSALTIIVLHSVLMIGISMVMMPAQTNGLNQLPPKLYPDGTAIMNTLQQVSGAIGTAVAITIMSAGQKAYMETAQGMGPEQMVASLTAGIQNAFVFGLIMACIGLLCSLFIRKAK
>NZ_CP007689.1|WP_003721295.1|1416461_1417397_-|ribose-phosphate-pyrophosphokinase
MAGKMKLFSVTSERPLATKIADYLDIPLCEVELQKFSDGEVKINIEESIRGTNAYVVQSMNSNVNERLMELLIMVDALKRASVHSINIIMPYYGYARQDRKARSREPITAKLMANLIQRAGANRLITVDLHAAQIQGFFNIPIDHLSAIPLIGDYLIENYGEKDVVVVAPDHSGVVRARRIADRLNAPIAILNRKPRPHEDEIMSVIGDVKGKVAIVVDDIIDTGVRATTSADILLEKGAVEVIACATHSVMAGNATERLQNSSIKEVITSDSIDLPEDKQFDKLTTISIGRILGRAIEGVQENRSLHPLF
>NZ_CP007689.1|WP_003721294.1|1417536_1418808_-|PTS-galactitol-transporter-subunit-IIC
MDIILDFFKYIIGLGVTVMMPIIITILGVIFRKKISVAFKAGLTVGVGFVGLGVITSLMLTTITPVTKALVENYNFKLTATDIGWGVGSSLAWGTEVVPFVFVAIIATNILMIAFKWTKTMDVDIWNYWQPLFIASALYLTTGSMIIAVLSSIINMAIIFKIADWTQKDVEDVLGLEGISLPQIQTTGWALVGYPMNWLLGKIPGVRKINWSTEKVQSRLGIFGEPMLMGLIIGGGLAAIAQMPLSQVLQTGVTIAASLVLIPRMVSLLMDGLTVISEAAHEFMEKRFPGRELFIGLDSAVGIGHPFVLSLGLLMIPITLILAFILPGNKVLPLADLTALPFYMIFAIVPSKGNLFRGIFTGIVIVIITLYLSGAAAPLMTELAGQIGYNIPKDAVEVTSLAVGTQWYTWIVYYGLHWFGGIL
>NZ_CP007689.1|WP_003727301.1|1418822_1419116_-|PTS-sugar-transporter-subunit-IIB
MKKKKIYVCCGTGIATSTVISKKVRAVLDEKRIPYEISQCTVQEVASKVSTSKPDIIVSSTTVTGDVGDVPVVIGRSFLTGLKKQETIDEILAILQD
>NZ_CP007689.1|WP_009930756.1|1419131_1420178_-|galactitol-1-phosphate-5-dehydrogenase
MKALKLYGKRDLRYEEADMPTIEEPDDVILKVKTVGICGSDISRYSKLGPYVPGMVWGHEFSGEVIEVGSEVTDIEIGDRAAGCPALYCGECEYCKKGEFARCRKLTVIGARHPGAYAEYIKLPAENVVKIPNELDYEAAALVEPSAVVVHGFYHTKLQAGDDVVVVGSGNIGLLAIQWAKVFGARRVIAIDVDDKKLALAKEVGADVVINSLKEDPLEVVAAHTDGLNADLVVEAAGSPITSAQVFAYAKKGGGVVFLGIPYADVTIERFYFEKIVRSELTVWGSWNAISAPFPGKEWQTTIHFLANKQINIEPMITHRLSLAEGPEVFERIYERNEFFGKVLFFPE
>NZ_CP007689.1|WP_012951245.1|1420174_1420825_-|ribulose-phosphate-3-epimerase
MAKIVPSVFGADIGRINEQLQVLEKNDIDLLHVDMMDGSFVPNIAFGPDQIKMMKKGTKLQFDVHMMVYEPDRYIPRLVEAGAHMITVHQEATTHLHRTIQLIKSYGVRAGVVLNPGTPPSTLEYVLDDIDCILLMTVNPGLGGQKFFQSSLEKIRKTKAYIGNRPIQIEVDGGVNAELAKECTLAGADLIVVGSYLFEGDIEANLEKLAKGVLTE
>NZ_CP007689.1|WP_003721290.1|1420835_1421234_-|hypothetical-protein
MGSFFASFVDWLIGSPGRFVVNLIEDNMLIFMVVVMIYATTILYAKWTLAYYLPKKMSQLAEMKTWELDELYAAWQTEKKALPWYILVPSRNEFWVKSARNAPESTKLLHFSQQKLKLSDKEKLQKIIEIQS
>NZ_CP007689.1|WP_003733191.1|1421250_1421718_-|PTS-sugar-transporter-subunit-IIA
MDVLEYFKEEMVRFSNEQNKEKLLAEMAEQLCEVGAVKPSYKDAVIKREKVFPTGLLTAHAGVAIPHTDSEHVIRPVVAVRILKKPVSFIEMASDNEAIDVRIVFMMALRSADEQLDMLQTLIQLIQDEEVMTTLLKAQETGDVLSAIEHFSKNN
>NZ_CP007689.1|WP_003733192.1|1421745_1422348_-|SIS-domain-containing-protein
MDKQAILNNIHQTWQEEANAISRLPEVTSEEALVKTVEKIAECTGKIVVAGCGTSGVAAKKLVHSFNCIERPAVFLTPSDAVHGTLGVLQKEDILILISKGGNTGELLNLIPACKTKGSTLIGVTENPDSVIAKEADIFFPVSVSKEPDPFNMLATASTMAVIASFDAVIVCLMTYMNYTKEQFSVIHPGGAVGNKLLNK
>NZ_CP007689.1|WP_003733193.1|1422351_1424412_-|BglG-family-transcription-antiterminator
MYLDNRSKTLFQEVIKNPNITNKQLEVKYKLSRYQISYSFQKVNEWLKWKNYPEVKRSKNGRFILEPELTALFSEKETRDPSVEYLPSENERANLILLMLLTSKEELSLAHFTTKIQVSKNTILRDLKVAQKLLPKETTVTYSRASGYQLAGSEWELRKVLTQVVSSVKEMFRGEHYFLSYSGIEKVQLMEIRRTLEEAEAMMQIKFTYEQIELLPYLLSVMFLRIRDRRLIDTAFHIDEKSLSDTREYHITDILLEKTGPVPEQERLFITLQLLTTNIFSGEILTEKLTEDLEKVVLTCLDLFEKKALVSLKNKHILIEKLLLHLKPAYYRIKYQMNLEDTLYEKFNQEFEALNFIVKEAFDPLAKFIGREIPAGEIFFISLFIGSDMIPQNDIYHKQKRAIVLCPSGVTFSKIMENILVKLFPEIHFYPTISVREYAFFKAEVDIVFSSIPLKDGENVFVVQPFMNDIEKTQLRQHVLQNLFGMGNQLTSIDKIMEVVERNADIKDPNAIRDGIIDILSANTATDENKRVKKVYLHDLITEDNIMICEDVKNYQEAIRLASQPLLLQQAITANYVKTMIDNHKFHDPYIIIGEDIAIPHAMPNAGVNRLAMSLLVVKNGVYFSETEQVHFVIVIAPVDKEQHIEALYQIVHLAENHQILDDLLENVTKEKIMQTINQLVIREDE
>NZ_CP007689.1|WP_047932806.1|1424520_1425171_-|transaldolase
MHLDSANLDDVKKIQASSIFKGITTNPTILVKEKCNRQTAINRILELTDKQVFVQTVGFSYEEILADARMLLAMFGKEKIAIKIPAHEAGINVIDTLKKEDKTIQILGTAIYSADQAIASAMAGADFVAPYVNRMSAANIDPFKEITQMRHFFDKKALKTQIMAASFKHSGQVMQAYESGADTVTIPYEIYSQMTNKVLAVEAIRVFNEDAVLYEK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP007689_2	2.6\|1415905\|35\|NZ_CP007689\|CRT	1415905-1415939	35	DQ003642	Listeria phage A006, complete genome	15712-15746	0	1.0
NZ_CP007689_2	2.7\|1415969\|36\|NZ_CP007689\|CRT	1415969-1416004	36	MT500540	Listeria phage LP-HM00113468, complete genome	683-718	0	1.0
NZ_CP007689_2	2.7\|1415969\|36\|NZ_CP007689\|CRT	1415969-1416004	36	NC_009812	Listeria phage B025, complete genome	3896-3931	0	1.0
NZ_CP007689_2	2.7\|1415969\|36\|NZ_CP007689\|CRT	1415969-1416004	36	KJ094023	Listeria phage LP-101, complete genome	3936-3971	0	1.0
NZ_CP007689_2	2.1\|1415904\|36\|NZ_CP007689\|PILER-CR,CRISPRCasFinder	1415904-1415939	36	DQ003642	Listeria phage A006, complete genome	15711-15746	1	0.972
NZ_CP007689_2	2.2\|1415968\|37\|NZ_CP007689\|PILER-CR,CRISPRCasFinder	1415968-1416004	37	NC_009812	Listeria phage B025, complete genome	3896-3932	1	0.973
NZ_CP007689_2	2.2\|1415968\|37\|NZ_CP007689\|PILER-CR,CRISPRCasFinder	1415968-1416004	37	KJ094023	Listeria phage LP-101, complete genome	3936-3972	1	0.973
NZ_CP007689_2	2.2\|1415968\|37\|NZ_CP007689\|PILER-CR,CRISPRCasFinder	1415968-1416004	37	MT500540	Listeria phage LP-HM00113468, complete genome	682-718	1	0.973
NZ_CP007689_2	2.3\|1416033\|36\|NZ_CP007689\|PILER-CR,CRISPRCasFinder	1416033-1416068	36	NC_021539	Listeria phage LP-030-2, complete genome	18926-18961	1	0.972
NZ_CP007689_2	2.3\|1416033\|36\|NZ_CP007689\|PILER-CR,CRISPRCasFinder	1416033-1416068	36	KJ094023	Listeria phage LP-101, complete genome	22882-22917	1	0.972
NZ_CP007689_2	2.5\|1416160\|36\|NZ_CP007689\|PILER-CR,CRISPRCasFinder	1416160-1416195	36	MH341453	Listeria phage PSU-VKH-LP041, complete genome	10139-10174	1	0.972
NZ_CP007689_2	2.7\|1415969\|36\|NZ_CP007689\|CRT	1415969-1416004	36	NZ_LR134403	Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence	213463-213498	1	0.972
NZ_CP007689_2	2.8\|1416034\|35\|NZ_CP007689\|CRT	1416034-1416068	35	NC_021539	Listeria phage LP-030-2, complete genome	18926-18960	1	0.971
NZ_CP007689_2	2.8\|1416034\|35\|NZ_CP007689\|CRT	1416034-1416068	35	KJ094023	Listeria phage LP-101, complete genome	22882-22916	1	0.971
NZ_CP007689_2	2.10\|1416161\|35\|NZ_CP007689\|CRT	1416161-1416195	35	MH341453	Listeria phage PSU-VKH-LP041, complete genome	10139-10173	1	0.971
NZ_CP007689_2	2.2\|1415968\|37\|NZ_CP007689\|PILER-CR,CRISPRCasFinder	1415968-1416004	37	NZ_LR134403	Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence	213463-213499	2	0.946
NZ_CP007689_2	2.3\|1416033\|36\|NZ_CP007689\|PILER-CR,CRISPRCasFinder	1416033-1416068	36	NC_009812	Listeria phage B025, complete genome	23381-23416	2	0.944
NZ_CP007689_2	2.5\|1416160\|36\|NZ_CP007689\|PILER-CR,CRISPRCasFinder	1416160-1416195	36	NC_009813	Listeria phage B054, complete genome	10139-10174	2	0.944
NZ_CP007689_2	2.8\|1416034\|35\|NZ_CP007689\|CRT	1416034-1416068	35	NC_009812	Listeria phage B025, complete genome	23381-23415	2	0.943
NZ_CP007689_2	2.10\|1416161\|35\|NZ_CP007689\|CRT	1416161-1416195	35	NC_009813	Listeria phage B054, complete genome	10139-10173	2	0.943
NZ_CP007689_2	2.7\|1415969\|36\|NZ_CP007689\|CRT	1415969-1416004	36	JN700520	Staphylococcus phage StB12, complete genome	6832-6867	5	0.861
NZ_CP007689_2	2.2\|1415968\|37\|NZ_CP007689\|PILER-CR,CRISPRCasFinder	1415968-1416004	37	JN700520	Staphylococcus phage StB12, complete genome	6832-6868	6	0.838
NZ_CP007689_2	2.7\|1415969\|36\|NZ_CP007689\|CRT	1415969-1416004	36	MW084976	Bacillus phage Kirov, complete genome	27565-27600	8	0.778
NZ_CP007689_2	2.2\|1415968\|37\|NZ_CP007689\|PILER-CR,CRISPRCasFinder	1415968-1416004	37	MW084976	Bacillus phage Kirov, complete genome	27565-27601	9	0.757
NZ_CP007689_2	2.6\|1415905\|35\|NZ_CP007689\|CRT	1415905-1415939	35	NZ_CP029455	Bacillus cereus strain FORC087 plasmid pFORC087.1, complete sequence	130632-130666	11	0.686
NZ_CP007689_2	2.6\|1415905\|35\|NZ_CP007689\|CRT	1415905-1415939	35	NZ_CP015592	Bacillus cereus strain AR156 plasmid pAR460, complete sequence	17622-17656	11	0.686
NZ_CP007689_2	2.6\|1415905\|35\|NZ_CP007689\|CRT	1415905-1415939	35	NZ_CP009368	Bacillus cereus strain FM1 plasmid unnamed, complete sequence	31860-31894	11	0.686
NZ_CP007689_2	2.6\|1415905\|35\|NZ_CP007689\|CRT	1415905-1415939	35	NZ_CP009336	Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence	338888-338922	11	0.686

1. spacer 2.6|1415905|35|NZ_CP007689|CRT matches to DQ003642 (Listeria phage A006, complete genome) position: , mismatch: 0, identity: 1.0

gaaattgtaaaatctatatccgttgattcaacaaa	CRISPR spacer
gaaattgtaaaatctatatccgttgattcaacaaa	Protospacer
***********************************

2. spacer 2.7|1415969|36|NZ_CP007689|CRT matches to MT500540 (Listeria phage LP-HM00113468, complete genome) position: , mismatch: 0, identity: 1.0

ttaatttgatagtcataatttatttcctcctatttt	CRISPR spacer
ttaatttgatagtcataatttatttcctcctatttt	Protospacer
************************************

3. spacer 2.7|1415969|36|NZ_CP007689|CRT matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 0, identity: 1.0

ttaatttgatagtcataatttatttcctcctatttt	CRISPR spacer
ttaatttgatagtcataatttatttcctcctatttt	Protospacer
************************************

4. spacer 2.7|1415969|36|NZ_CP007689|CRT matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 0, identity: 1.0

ttaatttgatagtcataatttatttcctcctatttt	CRISPR spacer
ttaatttgatagtcataatttatttcctcctatttt	Protospacer
************************************

5. spacer 2.1|1415904|36|NZ_CP007689|PILER-CR,CRISPRCasFinder matches to DQ003642 (Listeria phage A006, complete genome) position: , mismatch: 1, identity: 0.972

cgaaattgtaaaatctatatccgttgattcaacaaa	CRISPR spacer
agaaattgtaaaatctatatccgttgattcaacaaa	Protospacer
 ***********************************

6. spacer 2.2|1415968|37|NZ_CP007689|PILER-CR,CRISPRCasFinder matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 1, identity: 0.973

cttaatttgatagtcataatttatttcctcctatttt	CRISPR spacer
tttaatttgatagtcataatttatttcctcctatttt	Protospacer
.************************************

7. spacer 2.2|1415968|37|NZ_CP007689|PILER-CR,CRISPRCasFinder matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 1, identity: 0.973

cttaatttgatagtcataatttatttcctcctatttt	CRISPR spacer
tttaatttgatagtcataatttatttcctcctatttt	Protospacer
.************************************

8. spacer 2.2|1415968|37|NZ_CP007689|PILER-CR,CRISPRCasFinder matches to MT500540 (Listeria phage LP-HM00113468, complete genome) position: , mismatch: 1, identity: 0.973

cttaatttgatagtcataatttatttcctcctatttt	CRISPR spacer
tttaatttgatagtcataatttatttcctcctatttt	Protospacer
.************************************

9. spacer 2.3|1416033|36|NZ_CP007689|PILER-CR,CRISPRCasFinder matches to NC_021539 (Listeria phage LP-030-2, complete genome) position: , mismatch: 1, identity: 0.972

tatagaaaggagttgatacagtgaaggatgttttag	CRISPR spacer
tatagaaaggagttgagacagtgaaggatgttttag	Protospacer
**************** *******************

10. spacer 2.3|1416033|36|NZ_CP007689|PILER-CR,CRISPRCasFinder matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 1, identity: 0.972

tatagaaaggagttgatacagtgaaggatgttttag	CRISPR spacer
tatagaaaggagttgagacagtgaaggatgttttag	Protospacer
**************** *******************

11. spacer 2.5|1416160|36|NZ_CP007689|PILER-CR,CRISPRCasFinder matches to MH341453 (Listeria phage PSU-VKH-LP041, complete genome) position: , mismatch: 1, identity: 0.972

cttgtaacccatcgctgtccctttgacaaaaatcgc	CRISPR spacer
cttgtaacccatcgctgttcctttgacaaaaatcgc	Protospacer
******************.*****************

12. spacer 2.7|1415969|36|NZ_CP007689|CRT matches to NZ_LR134403 (Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence) position: , mismatch: 1, identity: 0.972

ttaatttgatagtcataatttatttcctcctatttt	CRISPR spacer
ttaatttgatagtcataatctatttcctcctatttt	Protospacer
*******************.****************

13. spacer 2.8|1416034|35|NZ_CP007689|CRT matches to NC_021539 (Listeria phage LP-030-2, complete genome) position: , mismatch: 1, identity: 0.971

atagaaaggagttgatacagtgaaggatgttttag	CRISPR spacer
atagaaaggagttgagacagtgaaggatgttttag	Protospacer
*************** *******************

14. spacer 2.8|1416034|35|NZ_CP007689|CRT matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 1, identity: 0.971

atagaaaggagttgatacagtgaaggatgttttag	CRISPR spacer
atagaaaggagttgagacagtgaaggatgttttag	Protospacer
*************** *******************

15. spacer 2.10|1416161|35|NZ_CP007689|CRT matches to MH341453 (Listeria phage PSU-VKH-LP041, complete genome) position: , mismatch: 1, identity: 0.971

ttgtaacccatcgctgtccctttgacaaaaatcgc	CRISPR spacer
ttgtaacccatcgctgttcctttgacaaaaatcgc	Protospacer
*****************.*****************

16. spacer 2.2|1415968|37|NZ_CP007689|PILER-CR,CRISPRCasFinder matches to NZ_LR134403 (Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence) position: , mismatch: 2, identity: 0.946

cttaatttgatagtcataatttatttcctcctatttt	CRISPR spacer
tttaatttgatagtcataatctatttcctcctatttt	Protospacer
.*******************.****************

17. spacer 2.3|1416033|36|NZ_CP007689|PILER-CR,CRISPRCasFinder matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 2, identity: 0.944

tatagaaaggagttgatacagtgaaggatgttttag	CRISPR spacer
tatagaaaggagttgagatagtgaaggatgttttag	Protospacer
**************** *.*****************

18. spacer 2.5|1416160|36|NZ_CP007689|PILER-CR,CRISPRCasFinder matches to NC_009813 (Listeria phage B054, complete genome) position: , mismatch: 2, identity: 0.944

cttgtaacccatcgctgtccctttgacaaaaatcgc	CRISPR spacer
cttgtaacccatcgccgttcctttgacaaaaatcgc	Protospacer
***************.**.*****************

19. spacer 2.8|1416034|35|NZ_CP007689|CRT matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 2, identity: 0.943

atagaaaggagttgatacagtgaaggatgttttag	CRISPR spacer
atagaaaggagttgagatagtgaaggatgttttag	Protospacer
*************** *.*****************

20. spacer 2.10|1416161|35|NZ_CP007689|CRT matches to NC_009813 (Listeria phage B054, complete genome) position: , mismatch: 2, identity: 0.943

ttgtaacccatcgctgtccctttgacaaaaatcgc	CRISPR spacer
ttgtaacccatcgccgttcctttgacaaaaatcgc	Protospacer
**************.**.*****************

21. spacer 2.7|1415969|36|NZ_CP007689|CRT matches to JN700520 (Staphylococcus phage StB12, complete genome) position: , mismatch: 5, identity: 0.861

ttaatttga-tagtcataatttatttcctcctatttt	CRISPR spacer
-tagtttgattagtcattatttacttcctcctattta	Protospacer
 **.***** ******* *****.************

22. spacer 2.2|1415968|37|NZ_CP007689|PILER-CR,CRISPRCasFinder matches to JN700520 (Staphylococcus phage StB12, complete genome) position: , mismatch: 6, identity: 0.838

cttaatttga-tagtcataatttatttcctcctatttt	CRISPR spacer
-atagtttgattagtcattatttacttcctcctattta	Protospacer
  **.***** ******* *****.************

23. spacer 2.7|1415969|36|NZ_CP007689|CRT matches to MW084976 (Bacillus phage Kirov, complete genome) position: , mismatch: 8, identity: 0.778

ttaatttgatagtcataatttatttcctcctatttt	CRISPR spacer
ttcttacgatagccattatttatttcctcctattaa	Protospacer
**  * .*****.*** *****************

24. spacer 2.2|1415968|37|NZ_CP007689|PILER-CR,CRISPRCasFinder matches to MW084976 (Bacillus phage Kirov, complete genome) position: , mismatch: 9, identity: 0.757

cttaatttgatagtcataatttatttcctcctatttt	CRISPR spacer
tttcttacgatagccattatttatttcctcctattaa	Protospacer
.**  * .*****.*** *****************

25. spacer 2.6|1415905|35|NZ_CP007689|CRT matches to NZ_CP029455 (Bacillus cereus strain FORC087 plasmid pFORC087.1, complete sequence) position: , mismatch: 11, identity: 0.686

gaaattgtaaaatctatatccgttgattcaacaaa	CRISPR spacer
aagattttaaaatctatatcggttgatttttttct	Protospacer
.*.*** ************* *******.  .

26. spacer 2.6|1415905|35|NZ_CP007689|CRT matches to NZ_CP015592 (Bacillus cereus strain AR156 plasmid pAR460, complete sequence) position: , mismatch: 11, identity: 0.686

gaaattgtaaaatctatatccgttgattcaacaaa	CRISPR spacer
aagattttaaaatctatatcggttgattttttctt	Protospacer
.*.*** ************* *******.  .

27. spacer 2.6|1415905|35|NZ_CP007689|CRT matches to NZ_CP009368 (Bacillus cereus strain FM1 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gaaattgtaaaatctatatccgttgattcaacaaa	CRISPR spacer
aagattttaaaatctatatcggttgatttttttct	Protospacer
.*.*** ************* *******.  .

28. spacer 2.6|1415905|35|NZ_CP007689|CRT matches to NZ_CP009336 (Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.686

gaaattgtaaaatctatatccgttgattcaacaaa	CRISPR spacer
aagattttaaaatctatatcggttgatttttttct	Protospacer
.*.*** ************* *******.  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

635406 : 696610

Streptococcus_phage(16.67%)

tRNA,protease

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003732816.1\|635406_637113_-\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_003723454.1\|637152_638415_-\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_047932493.1\|638428_639571_-	1-deoxy-D-xylulose-5-phosphate reductoisomerase	NA	NA	NA	NA
WP_003727496.1\|639585_640374_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_003732812.1\|640387_641146_-	isoprenyl transferase	R9W0U9	Flavobacterium_phage	4.4e-22	42.1
WP_003723450.1\|641375_641933_-	ribosome recycling factor	NA	NA	NA	NA
WP_003723449.1\|641932_642661_-	UMP kinase	NA	NA	NA	NA
WP_003723448.1\|642953_643328_+	hypothetical protein	NA	NA	NA	NA
WP_072217143.1\|643305_644511_+	helicase SNF2	L0P6E9	Lactobacillus_phage	3.7e-92	47.1
WP_003723446.1\|644500_645805_+	DUF3440 domain-containing protein	A0A220GKF8	Streptococcus_phage	9.5e-134	52.1
WP_003723445.1\|645814_646321_+	ParB-like nuclease domain-containing protein	A0A220GKT8	Streptococcus_phage	4.0e-56	66.7
WP_003723444.1\|646342_647074_+	methyltransferase domain-containing protein	A0A1X9I6N4	Streptococcus_phage	1.2e-80	59.1
WP_003723443.1\|647092_647935_+	DUF2785 domain-containing protein	NA	NA	NA	NA
WP_003723442.1\|647985_648225_-	YneF family protein	NA	NA	NA	NA
WP_047932497.1\|648445_650440_-	transketolase	NA	NA	NA	NA
WP_003723440.1\|650586_650814_-	DUF896 domain-containing protein	NA	NA	NA	NA
WP_003723439.1\|650905_651235_-	cell division suppressor protein YneA	NA	NA	NA	NA
WP_003723438.1\|651392_652007_+	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	9.3e-15	62.1
WP_031674623.1\|652036_652558_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003723436.1\|652601_653897_-	arsenical efflux pump membrane protein ArsB	A0A2H4PQU3	Staphylococcus_phage	1.8e-145	61.6
WP_003723435.1\|654040_655375_-	type I glutamate--ammonia ligase	A0A1V0SJ53	Klosneuvirus	2.0e-06	26.4
WP_003719570.1\|655445_655814_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_010989728.1\|656017_657244_-	methionine gamma-lyase family protein	NA	NA	NA	NA
WP_022741839.1\|657236_658460_-	GTPase HflX	NA	NA	NA	NA
WP_003719566.1\|658570_658804_-	RNA chaperone Hfq	NA	NA	NA	NA
WP_012951578.1\|658926_659844_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_003723738.1\|659969_661646_-	glycerol-3-phosphate dehydrogenase/oxidase	NA	NA	NA	NA
WP_012951577.1\|661878_662577_-	glycerophosphodiester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	9.9e-13	32.4
WP_026749937.1\|662789_664658_+	peptidoglycan O-acetyltransferase OatA	B5WZU0	Pseudomonas_phage	6.5e-43	31.9
WP_031674621.1\|664691_666506_-	class 1 internalin InlK	NA	NA	NA	NA
WP_047932505.1\|666837_668571_-	LapB repeat-containing protein	NA	NA	NA	NA
WP_009913867.1\|668897_669365_-	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_010989723.1\|669447_671907_-	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	4.7e-102	31.6
WP_003723731.1\|671903_673871_-	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	6.7e-123	42.5
WP_003732802.1\|674051_674459_-	CoA-binding protein	NA	NA	NA	NA
WP_031674617.1\|674616_675213_+	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_003724131.1\|675254_676127_-	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_003724130.1\|676129_676441_-	hypothetical protein	NA	NA	NA	NA
WP_003724129.1\|676462_676882_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_003726695.1\|676984_677764_-	GTP-sensing pleiotropic transcriptional regulator CodY	NA	NA	NA	NA
WP_031674616.1\|677784_679194_-\|protease	ATP-dependent protease ATPase subunit HslU	W6AS21	Erwinia_phage	1.7e-43	27.7
WP_003724001.1\|679207_679747_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_009911635.1\|679767_680670_-	tyrosine recombinase XerC	A0A097EYL9	Mycobacterium_phage	1.2e-13	28.6
WP_009924616.1\|680952_682257_-\|tRNA	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	NA	NA	NA	NA
WP_009924617.1\|682319_684398_-	type I DNA topoisomerase	A0A1V0SB35	Catovirus	1.4e-107	37.7
WP_003723892.1\|684668_685529_-	DNA-protecting protein DprA	NA	NA	NA	NA
WP_003723891.1\|685662_686448_-	ribonuclease HII	G4YAY0	Emiliania_huxleyi_virus	3.0e-26	39.2
WP_003723890.1\|686444_687308_-	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_003723889.1\|687317_687860_-	type I signal peptidase SipZ	NA	NA	NA	NA
WP_003723888.1\|687961_688531_-	type I signal peptidase SipY	NA	NA	NA	NA
WP_003723887.1\|688565_689132_-	type I signal peptidase SipX	NA	NA	NA	NA
WP_003723886.1\|689250_690510_-\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.4e-145	63.2
WP_047932516.1\|690695_691979_-	trigger factor	NA	NA	NA	NA
WP_014600790.1\|692093_693032_-	hypothetical protein	NA	NA	NA	NA
WP_003732795.1\|693293_693959_-	hypothetical protein	NA	NA	NA	NA
WP_047932518.1\|693976_694510_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_047932521.1\|694628_694844_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003723563.1\|694994_695390_+	helix-turn-helix transcriptional regulator	A9D9J6	Lactobacillus_prophage	1.3e-14	57.4
WP_003723562.1\|695470_696610_+\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_2

829633 : 837055

Hokovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003736259.1\|829633_831190_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	7.8e-18	29.2
WP_003730540.1\|831318_831723_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_009925410.1\|831782_832091_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_031674562.1\|832103_832928_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	8.8e-69	53.3
WP_003721509.1\|832939_834430_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	9.5e-114	49.7
WP_026749862.1\|834638_835652_-	glycosyltransferase	A0A1V0SAH6	Catovirus	7.9e-11	32.0
WP_031674558.1\|835666_836650_-	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	1.2e-11	33.8
WP_003721506.1\|836671_837055_-	glycerol-3-phosphate cytidylyltransferase	A0A1V0SGE7	Hokovirus	1.4e-16	40.7

DBSCAN-SWA_3

1790764 : 1799050

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003722243.1\|1790764_1791331_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	7.0e-25	35.9
WP_003722244.1\|1791327_1792377_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.0e-61	43.2
WP_003722245.1\|1792395_1793823_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.1e-53	34.6
WP_031671881.1\|1793807_1796027_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.7e-159	41.1
WP_031671882.1\|1796019_1796703_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_015454911.1\|1796706_1796952_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_014931516.1\|1796963_1797677_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3F9V5	Synechococcus_phage	8.8e-41	37.8
WP_020246648.1\|1797757_1799050_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	2.5e-17	33.0

DBSCAN-SWA_4

2463142 : 2470986

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003722604.1\|2463142_2464114_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	5.2e-52	39.4
WP_003722605.1\|2464121_2465090_-	YvcK family protein	A1IMD5	Streptococcus_phage	6.7e-68	43.3
WP_010990001.1\|2465091_2465967_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	3.2e-08	29.7
WP_031672028.1\|2466074_2467805_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	3.3e-174	53.3
WP_009930954.1\|2467846_2468908_-	galactose mutarotase	NA	NA	NA	NA
WP_012952019.1\|2468924_2469908_-	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	5.8e-51	37.2
WP_003722610.1\|2470026_2470986_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.0e-88	53.7

DBSCAN-SWA_5

2557446 : 2627817

Listeria_phage(84.75%)

holin,protease,integrase,terminase,tail,tRNA

attL 2589277:2589326|attR 2627905:2627954

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003723609.1\|2557446_2559117_-\|tRNA	arginine--tRNA ligase	NA	NA	NA	NA
WP_003723610.1\|2559113_2559563_-	DUF1934 domain-containing protein	NA	NA	NA	NA
WP_031674805.1\|2559640_2560294_-\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_003723612.1\|2560367_2560553_+	4-oxalocrotonate tautomerase	NA	NA	NA	NA
WP_009924630.1\|2560587_2561910_-	HD domain-containing protein	A0A1B1ISR1	uncultured_Mediterranean_phage	2.6e-30	33.2
WP_003723614.1\|2561924_2562761_-	lipoyl-[GcvH]:protein N-lipoyltransferase	NA	NA	NA	NA
WP_003729274.1\|2563078_2563279_-	hypothetical protein	NA	NA	NA	NA
WP_003723616.1\|2563300_2563624_-	YxeA family protein	NA	NA	NA	NA
WP_077421966.1\|2563778_2565440_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003726112.1\|2565575_2566190_-	SdpI family protein	NA	NA	NA	NA
WP_009926161.1\|2566213_2566846_-	nicotinamidase	NA	NA	NA	NA
WP_003723621.1\|2566846_2567371_-	dihydrofolate reductase	NA	NA	NA	NA
WP_012952036.1\|2567373_2568372_-	zinc-binding alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_003723623.1\|2568468_2568741_-	hypothetical protein	NA	NA	NA	NA
WP_003723624.1\|2568789_2569701_-	cation transporter	NA	NA	NA	NA
WP_047933314.1\|2569826_2574419_-	collagen binding domain-containing protein	NA	NA	NA	NA
WP_003733264.1\|2574639_2575467_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_047933315.1\|2575581_2576457_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_047933317.1\|2576467_2576761_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_003733262.1\|2576793_2576955_-	hypothetical protein	NA	NA	NA	NA
WP_003723280.1\|2577023_2577692_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.0e-38	42.0
WP_047933321.1\|2577691_2578780_-	ABC transporter permease	NA	NA	NA	NA
WP_047933324.1\|2578858_2580238_-	HAMP domain-containing sensor histidine kinase	W8CYF6	Bacillus_phage	2.0e-57	47.5
WP_047933328.1\|2580234_2580912_-	response regulator transcription factor	W8CYM9	Bacillus_phage	4.4e-58	47.5
WP_014931680.1\|2580958_2581744_-	formate dehydrogenase accessory sulfurtransferase FdhD	NA	NA	NA	NA
WP_003723285.1\|2581805_2582282_-	DUF1641 domain-containing protein	NA	NA	NA	NA
WP_046335584.1\|2582281_2585269_-	formate dehydrogenase subunit alpha	NA	NA	NA	NA
WP_009931305.1\|2585767_2586610_+	S-adenosyl-l-methionine hydroxide adenosyltransferase family protein	NA	NA	NA	NA
WP_003733258.1\|2586657_2588139_-	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_003723289.1\|2588239_2589127_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
2589277:2589326	attL	NA	NA	NA	NA
WP_031667946.1\|2589759_2590023_+	anti-CRISPR protein AcrIIA4	A0A2D0TCG7	unidentified_phage	4.6e-40	96.6
WP_047933338.1\|2590027_2590477_+	anti-CRISPR protein AcrIIA1	Q9T196	Listeria_phage	1.3e-74	98.0
WP_047933342.1\|2590560_2590755_-	hypothetical protein	NA	NA	NA	NA
WP_003733663.1\|2590855_2591701_-	M15 family metallopeptidase	A0A059T7Y8	Listeria_phage	2.7e-137	94.7
WP_003722522.1\|2591700_2591982_-\|holin	holin	A8ASL4	Listeria_phage	3.4e-41	94.6
WP_003722523.1\|2591994_2592360_-	hypothetical protein	Q9T1A0	Listeria_phage	7.4e-12	100.0
WP_047933347.1\|2592398_2594564_-\|tail	phage tail protein	A8ATW1	Listeria_phage	0.0e+00	94.2
WP_047933349.1\|2594576_2596145_-\|tail	phage tail family protein	A8ATW0	Listeria_phage	1.3e-302	98.5
WP_047933352.1\|2596141_2600932_-\|tail	phage tail tape measure protein	A8ATV9	Listeria_phage	0.0e+00	94.2
WP_072225507.1\|2600936_2601248_-	hypothetical protein	A8ATV8	Listeria_phage	1.2e-42	98.9
WP_015987409.1\|2601244_2601676_-	hypothetical protein	A8ATV7	Listeria_phage	9.6e-75	100.0
WP_015987408.1\|2601731_2602418_-	Ig domain-containing protein	A8ATV6	Listeria_phage	9.4e-117	100.0
WP_003725064.1\|2602422_2602794_-	hypothetical protein	A8ATV5	Listeria_phage	8.5e-64	100.0
WP_015987407.1\|2602790_2603108_-	HK97 gp10 family phage protein	A8ATV4	Listeria_phage	9.9e-53	100.0
WP_015987430.1\|2603097_2603463_-	hypothetical protein	A8ATV3	Listeria_phage	4.4e-65	100.0
WP_012951937.1\|2603462_2603816_-	hypothetical protein	A8ATV2	Listeria_phage	7.6e-62	100.0
WP_172425835.1\|2603816_2603984_-	hypothetical protein	A8ATV1	Listeria_phage	1.7e-11	100.0
WP_015987427.1\|2603997_2604870_-	F420-dependent oxidoreductase	A8ATV0	Listeria_phage	1.2e-161	100.0
WP_015987425.1\|2604892_2605447_-	hypothetical protein	A8ATU9	Listeria_phage	2.3e-89	100.0
WP_015987421.1\|2605542_2606583_-	hypothetical protein	A8ATU8	Listeria_phage	1.6e-200	100.0
WP_015987416.1\|2606587_2608144_-	hypothetical protein	A8ATU7	Listeria_phage	4.8e-302	100.0
WP_047933366.1\|2608158_2609505_-\|terminase	PBSX family phage terminase large subunit	A8ATU6	Listeria_phage	5.9e-264	99.5
WP_015987406.1\|2609470_2610211_-	hypothetical protein	A8ATU5	Listeria_phage	3.7e-135	100.0
WP_012951944.1\|2610250_2610478_-	hypothetical protein	A8AU06	Listeria_phage	1.5e-34	100.0
WP_047933369.1\|2610558_2611191_-	hypothetical protein	A8AU05	Listeria_phage	5.3e-114	99.5
WP_015967178.1\|2611372_2611807_-	hypothetical protein	A8AU03	Listeria_phage	5.1e-76	100.0
WP_015967177.1\|2611825_2611990_-	hypothetical protein	A8AU02	Listeria_phage	3.9e-21	100.0
WP_003769966.1\|2612118_2612523_-	endodeoxyribonuclease	A8AU00	Listeria_phage	5.4e-72	100.0
WP_014601286.1\|2612488_2612629_-	BH0509 family protein	A8ATZ9	Listeria_phage	2.6e-18	100.0
WP_015967175.1\|2612625_2612931_-	hypothetical protein	A8ATZ8	Listeria_phage	1.7e-46	100.0
WP_015967174.1\|2612962_2613445_-	single-stranded DNA-binding protein	A8ATZ7	Listeria_phage	1.1e-82	100.0
WP_015967173.1\|2613441_2613843_-	hypothetical protein	A8ATZ6	Listeria_phage	1.4e-67	100.0
WP_015967170.1\|2614286_2614685_-	hypothetical protein	A8ATZ3	Listeria_phage	4.4e-66	100.0
WP_047933379.1\|2614681_2614891_-	hypothetical protein	A8ATE0	Listeria_phage	3.5e-30	92.8
WP_023552342.1\|2614993_2615584_-	pentapeptide repeat-containing protein	A0A060AFJ6	Listeria_phage	3.7e-29	67.3
WP_047933382.1\|2615580_2615790_-	hypothetical protein	A8ATE0	Listeria_phage	7.7e-30	91.3
WP_047933386.1\|2615786_2616302_-	hypothetical protein	C9E2P0	Enterococcus_phage	1.1e-32	46.2
WP_047933389.1\|2616405_2616624_-	hypothetical protein	NA	NA	NA	NA
WP_047933392.1\|2616620_2617214_-	DUF1642 domain-containing protein	A8ATD8	Listeria_phage	5.9e-59	60.0
WP_047933393.1\|2617210_2617420_-	hypothetical protein	A8ASN7	Listeria_phage	2.8e-24	88.4
WP_047933395.1\|2617416_2617701_-	hypothetical protein	A0A059T7N1	Listeria_phage	5.2e-45	94.7
WP_009931092.1\|2617716_2617884_-	hypothetical protein	A8ASN5	Listeria_phage	8.9e-21	92.7
WP_047933398.1\|2617972_2618887_-	hypothetical protein	A0A0B5D175	Listeria_phage	1.3e-15	35.8
WP_047933399.1\|2618907_2619717_-	PD-(D/E)XK nuclease-like domain-containing protein	A0A290GJV0	Caldibacillus_phage	2.1e-78	54.3
WP_003753535.1\|2619670_2620552_-	hypothetical protein	A0A2P1JTZ5	Anoxybacillus_phage	3.4e-87	58.6
WP_003727754.1\|2620548_2620752_-	hypothetical protein	NA	NA	NA	NA
WP_010989962.1\|2620968_2621157_-	hypothetical protein	Q9T175	Listeria_phage	2.0e-21	79.0
WP_031644321.1\|2621258_2621465_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_047933406.1\|2621454_2621985_-	hypothetical protein	A0A0B5D173	Listeria_phage	3.9e-78	87.9
WP_003733683.1\|2622110_2622887_-	phage antirepressor Ant	A0A0B5D0I2	Listeria_phage	6.9e-140	97.7
WP_003733684.1\|2622950_2623148_+	hypothetical protein	Q9T179	Listeria_phage	4.0e-20	96.0
WP_003722567.1\|2623149_2623431_-	hypothetical protein	A8ATX8	Listeria_phage	1.8e-37	95.7
WP_003733686.1\|2623456_2623741_-	hypothetical protein	A0A0B5D168	Listeria_phage	4.5e-41	85.1
WP_003733687.1\|2623752_2623947_-	hypothetical protein	A0A059T6E5	Listeria_phage	1.4e-25	95.3
WP_003733688.1\|2623967_2624177_-	helix-turn-helix domain-containing protein	A0A0B5D0D3	Listeria_phage	3.5e-30	95.6
WP_003724014.1\|2624342_2624765_+	helix-turn-helix transcriptional regulator	A0A0B5CYL9	Listeria_phage	7.7e-69	98.6
WP_003724015.1\|2624780_2625206_+	ImmA/IrrE family metallo-endopeptidase	A0A0B5CTZ7	Listeria_phage	2.2e-76	100.0
WP_003724016.1\|2625220_2625928_+	hypothetical protein	A0A0B5CTT6	Listeria_phage	2.8e-124	100.0
WP_047933409.1\|2626653_2627817_+\|integrase	site-specific integrase	S5MNZ2	Brevibacillus_phage	5.8e-50	31.2
2627905:2627954	attR	NA	NA	NA	NA

DBSCAN-SWA_6

2789644 : 2799676

Tupanvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003722116.1\|2789644_2791798_-	DNA topoisomerase III	A0A1X9I6W8	Streptococcus_phage	4.0e-44	34.1
WP_015456051.1\|2791821_2793594_-	DNA helicase RecQ	A0A2K9L3P7	Tupanvirus	6.3e-80	37.1
WP_003722118.1\|2793754_2795221_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	8.0e-97	40.0
WP_003722119.1\|2795508_2796039_-	ADP-ribose-binding protein	A0A0K1L687	Scale_drop_disease_virus	2.6e-29	49.3
WP_031672065.1\|2796096_2797707_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	1.9e-46	29.5
WP_072215787.1\|2797885_2798194_+	hypothetical protein	NA	NA	NA	NA
WP_003725314.1\|2798221_2799676_+	glycoside hydrolase family 1 protein	A0A0B5JD41	Pandoravirus	1.9e-50	30.3

Anti-CRISPR protein detection

Acr_ID: NZ_CP007689.1|WP_031667946.1|2589759_2590023_+|anti-CRISPR-protein-AcrIIA4

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP007689.1|WP_031667946.1|2589759_2590023_+|anti-CRISPR-protein-AcrIIA4

2589759_2590023_+

87 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|14	0.9655172413793104	1	1.0

2557446-2627817

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP007689

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information