CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP009642	Burkholderia mallei strain India86-567-2 chromosome I, complete sequence	0 crisprs	WYL,DEDDh,DinG,csa3	0	0	9	0
NZ_CP009643	Burkholderia mallei strain India86-567-2 chromosome II, complete sequence	3 crisprs	cas3,csa3	0	0	5	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

74340 : 83577

unidentified_phage(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004194112.1\|74340_75888_+	polynucleotide adenylyltransferase PcnB	H7BUW3	unidentified_phage	4.3e-24	31.2
WP_004194373.1\|75924_76452_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_004194274.1\|76448_77132_+	deoxynucleoside kinase	A0A249XZR7	Enterococcus_phage	2.6e-05	26.0
WP_004194137.1\|77196_78012_+	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0N7HVJ8	Ostreococcus_lucimarinus_virus	8.8e-37	33.3
WP_004194350.1\|78187_80194_-	bifunctional anthranilate synthase component I family protein/class IV aminotransferase	S4VT78	Pandoravirus	9.7e-53	35.0
WP_004194374.1\|80227_81358_-	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	2.9e-22	27.6
WP_004194034.1\|81624_83577_-	molecular chaperone DnaK	A0A1V0SH73	Hokovirus	2.7e-148	49.2

DBSCAN-SWA_2

472248 : 527094

uncultured_Mediterranean_phage(21.43%)

plate,tRNA,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_045588992.1\|472248_473712_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	1.3e-78	38.1
WP_004195278.1\|473836_474772_-	RNA polymerase sigma factor RpoH	A0A248SJA5	Salicola_phage	1.6e-37	36.4
WP_011204221.1\|475136_475706_+	acyloxyacyl hydrolase	A0A2H4J0I5	uncultured_Caudovirales_phage	2.4e-09	27.4
WP_004200162.1\|475747_476134_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_004195273.1\|476460_478101_-	2-isopropylmalate synthase	NA	NA	NA	NA
WP_004522869.1\|477994_478258_+	hypothetical protein	NA	NA	NA	NA
WP_004195272.1\|478536_479358_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_004195270.1\|479998_480979_-	DNA-binding protein YbiB	NA	NA	NA	NA
WP_045588993.1\|480975_483825_-	nitrate reductase	NA	NA	NA	NA
WP_011204219.1\|483821_484217_-	nitrite reductase (NAD(P)H) small subunit	NA	NA	NA	NA
WP_004195264.1\|484285_486730_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_004195258.1\|487114_487759_+	maleylacetoacetate isomerase	NA	NA	NA	NA
WP_004195253.1\|487915_489235_-	signal recognition particle-docking protein FtsY	NA	NA	NA	NA
WP_004195251.1\|489486_490113_+	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	NA	NA	NA	NA
WP_004195249.1\|490223_490724_+	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	2.9e-30	44.7
WP_004195247.1\|490786_491053_+	YfhL family 4Fe-4S dicluster ferredoxin	A0A1B1IWY9	uncultured_Mediterranean_phage	1.4e-20	56.3
WP_011204217.1\|491231_492302_-	histidinol-phosphate transaminase	NA	NA	NA	NA
WP_004185241.1\|492390_492996_-\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_004200150.1\|493109_493724_-	50S ribosomal protein L25/general stress protein Ctc	NA	NA	NA	NA
WP_004195243.1\|493887_494844_-	ribose-phosphate pyrophosphokinase	A0A2K9L2G2	Tupanvirus	5.3e-41	35.5
WP_004195241.1\|495021_495903_-	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase	NA	NA	NA	NA
WP_011807613.1\|495936_496572_-	lipoprotein localization protein LolB	NA	NA	NA	NA
WP_004195237.1\|496568_498389_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_004195234.1\|498477_499296_+	bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase	NA	NA	NA	NA
WP_004195232.1\|499300_500407_+	A/G-specific adenine glycosylase	NA	NA	NA	NA
WP_004195230.1\|500794_501427_-\|protease	ATP-dependent protease	NA	NA	NA	NA
WP_004195227.1\|501453_502347_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	4.4e-05	30.8
WP_004195225.1\|502432_503401_-	HPr kinase/phosphorylase	NA	NA	NA	NA
WP_004534308.1\|503529_504039_-	PTS IIA-like nitrogen regulatory protein PtsN	NA	NA	NA	NA
WP_004195219.1\|504271_504631_-	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_004195216.1\|504780_506289_-	RNA polymerase factor sigma-54	NA	NA	NA	NA
WP_004195214.1\|506457_507234_-	LPS export ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.2e-22	28.3
WP_004195213.1\|507230_507896_-	lipopolysaccharide transport periplasmic protein LptA	NA	NA	NA	NA
WP_004195210.1\|507914_508529_-	LPS export ABC transporter periplasmic protein LptC	NA	NA	NA	NA
WP_004200146.1\|508534_509074_-	HAD family hydrolase	E3T535	Cafeteria_roenbergensis_virus	8.4e-12	28.0
WP_004195206.1\|509073_510057_-	KpsF/GutQ family sugar-phosphate isomerase	A0A2P0VNK5	Tetraselmis_virus	9.9e-43	37.5
WP_004195204.1\|510184_512194_+	potassium efflux system protein	NA	NA	NA	NA
WP_004195200.1\|512933_513518_+	LysE family translocator	NA	NA	NA	NA
WP_004195199.1\|513530_514388_+	DUF4743 domain-containing protein	NA	NA	NA	NA
WP_004195197.1\|514439_515321_+	formyltetrahydrofolate deformylase	M4QRX9	Synechococcus_phage	4.3e-13	35.7
WP_004195195.1\|515616_516702_-	membrane protein	NA	NA	NA	NA
WP_004195192.1\|516920_519788_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	3.9e-305	55.0
WP_004195190.1\|520001_521189_+	MFS transporter	NA	NA	NA	NA
WP_004204730.1\|521302_521893_+	single-stranded DNA-binding protein	C5IHK5	Burkholderia_virus	2.7e-48	87.7
WP_038802950.1\|522370_523490_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004204912.1\|523629_524112_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_004202808.1\|524191_526030_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004204910.1\|525993_527094_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA

DBSCAN-SWA_3

764619 : 829373

Bacillus_phage(13.33%)

terminase,protease,integrase,transposase

attL 763777:763795|attR 823108:823126

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
763777:763795	attL	NA	NA	NA	NA
WP_004191998.1\|764619_766083_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004195859.1\|766137_767478_+	ethanolamine ammonia-lyase subunit EutB	NA	NA	NA	NA
WP_004195860.1\|767474_768278_+	ethanolamine ammonia-lyase subunit EutC	NA	NA	NA	NA
WP_004195862.1\|768343_768589_+	hypothetical protein	NA	NA	NA	NA
WP_004556617.1\|768857_770378_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_004195866.1\|770450_770630_+	hypothetical protein	NA	NA	NA	NA
WP_004195868.1\|770673_771702_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004185233.1\|771820_772888_-	hypothetical protein	NA	NA	NA	NA
WP_004195870.1\|772916_774620_-	thiamine pyrophosphate-binding protein	NA	NA	NA	NA
WP_004195872.1\|774892_776029_+	hypothetical protein	NA	NA	NA	NA
WP_004195873.1\|776063_777452_-	L-serine ammonia-lyase	NA	NA	NA	NA
WP_004195875.1\|777485_778604_-	alginate lyase family protein	NA	NA	NA	NA
WP_004185207.1\|778639_778765_+	hypothetical protein	NA	NA	NA	NA
WP_004195877.1\|778755_781683_-	aminomethyl-transferring glycine dehydrogenase	M4QFZ1	Prochlorococcus_phage	2.8e-258	51.2
WP_004195879.1\|781987_782368_-	glycine cleavage system protein GcvH	NA	NA	NA	NA
WP_004202927.1\|782461_783580_-	glycine cleavage system aminomethyltransferase GcvT	NA	NA	NA	NA
WP_004195883.1\|784323_784683_-	lipoprotein	NA	NA	NA	NA
WP_004185221.1\|784854_785907_-	oxidoreductase	NA	NA	NA	NA
WP_004204377.1\|786420_787155_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_004195887.1\|787220_788015_-	hypothetical protein	NA	NA	NA	NA
WP_004195888.1\|788312_790415_+	UvrD-helicase domain-containing protein	A7KV33	Bacillus_phage	1.1e-94	34.8
WP_004202928.1\|790735_791635_-	cytochrome c	NA	NA	NA	NA
WP_004200089.1\|792052_793162_-\|integrase	site-specific integrase	A0A1S5NNJ1	Burkholderia_phage	6.5e-168	79.9
WP_038802950.1\|793252_794372_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004198375.1\|794652_795789_-	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_004198376.1\|795785_796127_-	PadR family transcriptional regulator	NA	NA	NA	NA
WP_004198377.1\|796854_798504_+	GMC family oxidoreductase	A0A1V0SI18	Klosneuvirus	2.0e-56	30.9
WP_004198379.1\|798588_799386_+	SDR family oxidoreductase	A0A2N9QUX2	Trichoplusia_ni_ascovirus	3.3e-12	28.8
WP_004198380.1\|799431_800241_+	hypothetical protein	NA	NA	NA	NA
WP_004198382.1\|800251_800644_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_004198383.1\|800699_802205_+	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_004197126.1\|802421_803681_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004197127.1\|803685_804564_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_004205008.1\|804560_805610_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_004197129.1\|805606_806329_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	3.8e-07	25.5
WP_004538585.1\|806701_807433_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	1.6e-05	25.3
WP_004199873.1\|807555_808515_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004197133.1\|808914_810015_-	porin	NA	NA	NA	NA
WP_004197137.1\|810552_813582_-	DEAD/DEAH box helicase family protein	A0A2K5B256	Erysipelothrix_phage	2.2e-181	38.7
WP_004197139.1\|813622_815638_-	site-specific DNA-methyltransferase	A0A2K5B2C1	Erysipelothrix_phage	3.3e-85	33.5
WP_004197141.1\|815892_816075_-	hypothetical protein	NA	NA	NA	NA
WP_004197145.1\|816110_817271_-	porin	NA	NA	NA	NA
WP_004197150.1\|817560_818238_-	response regulator	NA	NA	NA	NA
WP_004197153.1\|818248_819628_-	sensor histidine kinase	NA	NA	NA	NA
WP_004201276.1\|819705_820554_-	ABC transporter permease	NA	NA	NA	NA
WP_004199877.1\|820581_821379_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.5e-30	35.3
WP_004199878.1\|821462_822476_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004199879.1\|822633_823155_-	DUF2938 domain-containing protein	NA	NA	NA	NA
823108:823126	attR	NA	NA	NA	NA
WP_004199880.1\|823147_824023_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004199881.1\|824104_824533_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004201278.1\|824852_825635_-	flagellar biosynthetic protein FliR	NA	NA	NA	NA
WP_004199882.1\|825753_826026_-	flagellar biosynthesis protein FliQ	NA	NA	NA	NA
WP_038802950.1\|826650_827771_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004199888.1\|828132_828630_-\|terminase	terminase	K4NXI4	Burkholderia_phage	2.6e-55	100.0
WP_004199890.1\|828851_829373_-\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	1.9e-21	51.0

DBSCAN-SWA_4

2092326 : 2166871

Leptospira_phage(25.0%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004191232.1\|2092326_2094234_+\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	1.7e-123	37.5
WP_071810680.1\|2094283_2094808_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	4.1e-11	28.7
WP_004191477.1\|2095000_2095198_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_004192938.1\|2095228_2095588_+	50S ribosomal protein L20	NA	NA	NA	NA
WP_004191909.1\|2095736_2096750_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2H4UW22	Bodo_saltans_virus	7.8e-27	38.8
WP_004193113.1\|2096837_2099270_+\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_004197408.1\|2099342_2099747_+	integration host factor subunit alpha	A0A1P8CWT5	Bacillus_phage	2.8e-12	41.1
WP_004526841.1\|2099805_2100210_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_004205970.1\|2100331_2102296_-	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|2102408_2103528_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004192528.1\|2104316_2105519_-	DUF3443 domain-containing protein	NA	NA	NA	NA
WP_004205966.1\|2105529_2106021_-	DUF2844 domain-containing protein	NA	NA	NA	NA
WP_004205956.1\|2106370_2107576_+	outer membrane protein assembly factor BamC	NA	NA	NA	NA
WP_038802950.1\|2108374_2109495_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004193694.1\|2109916_2110207_+	hypothetical protein	NA	NA	NA	NA
WP_004191628.1\|2110256_2110514_-	hypothetical protein	NA	NA	NA	NA
WP_004192834.1\|2110662_2110941_-	hypothetical protein	NA	NA	NA	NA
WP_004192638.1\|2111179_2111902_-	YdcF family protein	NA	NA	NA	NA
WP_004199444.1\|2112102_2112420_+	hypothetical protein	NA	NA	NA	NA
WP_004521676.1\|2112578_2112836_-	hypothetical protein	NA	NA	NA	NA
WP_004199443.1\|2113041_2113443_-\|transposase	transposase	NA	NA	NA	NA
WP_004193481.1\|2113861_2114764_+	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	4.5e-10	23.6
WP_004192767.1\|2115182_2116511_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	5.3e-23	35.1
WP_004191876.1\|2116574_2118239_+	pseudouridine synthase	NA	NA	NA	NA
WP_004193908.1\|2118543_2119005_+	ribosome maturation factor RimP	NA	NA	NA	NA
WP_004193517.1\|2119001_2120477_+	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_004197388.1\|2120568_2123496_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	5.2e-23	25.3
WP_004199441.1\|2123601_2123970_+	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_011203915.1\|2123996_2124932_+\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_004193982.1\|2125202_2126762_-	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_004192058.1\|2126784_2128020_-	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004191557.1\|2128087_2129584_-	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_004192835.1\|2129683_2130181_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_004191941.1\|2130380_2130521_-	hypothetical protein	NA	NA	NA	NA
WP_004193111.1\|2130473_2132300_+	translational GTPase TypA	NA	NA	NA	NA
WP_004191889.1\|2132638_2135503_+	2-oxoglutarate dehydrogenase E1 component	NA	NA	NA	NA
WP_004192735.1\|2135630_2136905_+	2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase	NA	NA	NA	NA
WP_004191219.1\|2137004_2138435_+	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	1.9e-42	27.8
WP_004550551.1\|2138541_2139639_+	cell division protein ZapE	NA	NA	NA	NA
WP_004191720.1\|2139833_2140244_+\|transposase	transposase	NA	NA	NA	NA
WP_004193599.1\|2140480_2140942_-	DUF2147 domain-containing protein	NA	NA	NA	NA
WP_011203914.1\|2141185_2142865_-	ShlB/FhaC/HecB family hemolysin secretion/activation protein	NA	NA	NA	NA
WP_004192734.1\|2143015_2144281_-	collagen-like triple helix repeat-containing protein	NA	NA	NA	NA
WP_004191362.1\|2144330_2145884_-	collagen-like triple helix repeat-containing protein	NA	NA	NA	NA
WP_004521662.1\|2145783_2146098_+	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|2146410_2147530_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004192661.1\|2148897_2151270_+	penicillin acylase family protein	NA	NA	NA	NA
WP_162473478.1\|2151438_2151687_+	hypothetical protein	NA	NA	NA	NA
WP_004191146.1\|2152714_2152861_-	hypothetical protein	NA	NA	NA	NA
WP_004193126.1\|2152860_2153526_-	response regulator transcription factor	NA	NA	NA	NA
WP_004552809.1\|2153823_2154207_-	hypothetical protein	NA	NA	NA	NA
WP_073699454.1\|2154765_2154948_+	hypothetical protein	NA	NA	NA	NA
WP_004204696.1\|2155664_2158451_-	membrane protein	NA	NA	NA	NA
WP_044302806.1\|2158594_2158792_-	hypothetical protein	NA	NA	NA	NA
WP_004193791.1\|2159622_2160594_-	type 1 fimbrial protein	NA	NA	NA	NA
WP_004193303.1\|2160584_2163086_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_004191349.1\|2163143_2163914_-	molecular chaperone	NA	NA	NA	NA
WP_004187628.1\|2165650_2166871_-\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	7.8e-239	99.5

DBSCAN-SWA_5

2257189 : 2334713

Klosneuvirus(20.0%)

coat,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004191922.1\|2257189_2260057_+\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	2.8e-146	39.3
WP_004192544.1\|2260143_2261025_+	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	1.9e-69	47.9
WP_004526815.1\|2261085_2261703_-	DUF4136 domain-containing protein	NA	NA	NA	NA
WP_004191850.1\|2261791_2264185_-	CHASE2 domain-containing protein	NA	NA	NA	NA
WP_004192128.1\|2264195_2265560_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_004193573.1\|2265556_2266261_-	response regulator transcription factor	NA	NA	NA	NA
WP_004192096.1\|2266588_2266975_-	hypothetical protein	NA	NA	NA	NA
WP_004193727.1\|2267250_2267481_-	sulfurtransferase TusA family protein	NA	NA	NA	NA
WP_004192573.1\|2267645_2268683_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_004193713.1\|2268695_2269715_-	inositol 2-dehydrogenase	NA	NA	NA	NA
WP_004191536.1\|2269707_2270589_-	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_004192875.1\|2270833_2271883_+	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004192697.1\|2271983_2273129_+	ABC transporter permease	NA	NA	NA	NA
WP_004193469.1\|2273141_2273942_+	sugar ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.3e-13	28.4
WP_004191266.1\|2273955_2275956_+	5-dehydro-2-deoxygluconokinase	NA	NA	NA	NA
WP_004196072.1\|2275966_2277952_+	3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing)	NA	NA	NA	NA
WP_004192432.1\|2277948_2278869_+	myo-inosose-2 dehydratase	NA	NA	NA	NA
WP_004196071.1\|2278868_2279672_+	5-deoxy-glucuronate isomerase	NA	NA	NA	NA
WP_004193939.1\|2279788_2280493_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_045589034.1\|2280489_2282793_-	branched-chain amino acid ABC transporter ATP-binding protein/permease	A0A2R8FFL6	Cedratvirus	2.4e-07	26.2
WP_004204954.1\|2282785_2283712_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_004193685.1\|2283716_2284166_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_004196068.1\|2284066_2284411_-	hypothetical protein	NA	NA	NA	NA
WP_004192588.1\|2284407_2285556_-	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_004193399.1\|2285771_2286107_+	YbjQ family protein	NA	NA	NA	NA
WP_004193543.1\|2286206_2286758_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_004196065.1\|2287049_2287727_+	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|2290432_2291553_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_011807697.1\|2291583_2292300_-	YbfB/YjiJ family MFS transporter	NA	NA	NA	NA
WP_038796370.1\|2292446_2293400_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004204967.1\|2293903_2296528_-\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	5.5e-80	39.2
WP_080939634.1\|2296845_2297085_+	hypothetical protein	NA	NA	NA	NA
WP_004204969.1\|2297186_2298407_+	CoA transferase	NA	NA	NA	NA
WP_004534928.1\|2298730_2298940_-	hypothetical protein	NA	NA	NA	NA
WP_004193654.1\|2299217_2300927_+\|tRNA	glutamine--tRNA ligase/YqeY domain fusion protein	A0A222YZ70	Escherichia_phage	8.8e-188	57.5
WP_004192426.1\|2301258_2301741_-	NUDIX hydrolase	A0A2I6PFL2	Proteus_phage	3.7e-19	41.3
WP_004193860.1\|2301759_2302146_-	hypothetical protein	NA	NA	NA	NA
WP_004196725.1\|2304447_2304627_+	hypothetical protein	NA	NA	NA	NA
WP_004192265.1\|2304623_2305484_+	M15 family metallopeptidase	NA	NA	NA	NA
WP_004191662.1\|2305527_2306943_-	cytochrome-c peroxidase	NA	NA	NA	NA
WP_004193177.1\|2307176_2308760_+	acid phosphatase	NA	NA	NA	NA
WP_004192836.1\|2308957_2310151_+	trans-2-enoyl-CoA reductase family protein	NA	NA	NA	NA
WP_004191546.1\|2310769_2311957_+	HlyD family secretion protein	NA	NA	NA	NA
WP_004192651.1\|2312129_2313749_+	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_004192810.1\|2315738_2316371_-	response regulator transcription factor	NA	NA	NA	NA
WP_004552891.1\|2316371_2318453_-	response regulator	A0A1V0SGR3	Hokovirus	1.7e-12	26.8
WP_004196717.1\|2318863_2319829_-\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004191504.1\|2322301_2323141_-	molecular chaperone	NA	NA	NA	NA
WP_004526783.1\|2323158_2323683_-\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004191870.1\|2323759_2324320_-\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004192149.1\|2324372_2324918_-\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004542449.1\|2324904_2325090_-	hypothetical protein	NA	NA	NA	NA
WP_004531175.1\|2325175_2325397_-	hypothetical protein	NA	NA	NA	NA
WP_004196705.1\|2325734_2326628_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004196700.1\|2327134_2328331_+	MFS transporter	NA	NA	NA	NA
WP_004192394.1\|2328375_2329368_+	amidohydrolase family protein	NA	NA	NA	NA
WP_004193855.1\|2329835_2330117_+	H-NS histone family protein	NA	NA	NA	NA
WP_004191144.1\|2330369_2330639_-	hypothetical protein	NA	NA	NA	NA
WP_004193170.1\|2331533_2332847_-	divalent metal cation transporter	NA	NA	NA	NA
WP_038802950.1\|2333593_2334713_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

DBSCAN-SWA_6

2886552 : 2970510

Streptococcus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004191998.1\|2886552_2888016_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004199567.1\|2888124_2888694_-	phasin family protein	NA	NA	NA	NA
WP_004557110.1\|2889363_2890485_+	D-alanyl-D-alanine endopeptidase	NA	NA	NA	NA
WP_004191998.1\|2890604_2892068_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004192702.1\|2892324_2894094_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	6.8e-34	23.8
WP_080939637.1\|2894401_2895652_-	dihydrolipoyllysine-residue acetyltransferase	NA	NA	NA	NA
WP_004199569.1\|2895784_2898481_-	pyruvate dehydrogenase (acetyl-transferring), homodimeric type	NA	NA	NA	NA
WP_004192045.1\|2898612_2898834_-	hypothetical protein	NA	NA	NA	NA
WP_004557112.1\|2898753_2901264_+	PAS domain S-box protein	NA	NA	NA	NA
WP_004193928.1\|2901260_2901899_+	response regulator transcription factor	NA	NA	NA	NA
WP_004192825.1\|2902215_2903073_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	4.1e-37	39.9
WP_004199570.1\|2903029_2903245_-	hypothetical protein	NA	NA	NA	NA
WP_004191126.1\|2903774_2905874_+	M3 family metallopeptidase	A0A1V0SD92	Indivirus	1.7e-39	21.8
WP_004191702.1\|2906103_2907306_-	DNA polymerase IV	NA	NA	NA	NA
WP_004192547.1\|2907258_2907543_+	hypothetical protein	NA	NA	NA	NA
WP_004193983.1\|2908035_2909316_+	NarK/NasA family nitrate transporter	NA	NA	NA	NA
WP_004192248.1\|2909359_2910745_+	NarK family nitrate/nitrite MFS transporter	NA	NA	NA	NA
WP_004193149.1\|2910995_2914721_+	nitrate reductase subunit alpha	NA	NA	NA	NA
WP_004193619.1\|2914717_2916271_+	nitrate reductase subunit beta	A0A077SL61	Escherichia_phage	2.9e-20	46.5
WP_004192818.1\|2916267_2916972_+	nitrate reductase molybdenum cofactor assembly chaperone	NA	NA	NA	NA
WP_004191967.1\|2917008_2917695_+	respiratory nitrate reductase subunit gamma	NA	NA	NA	NA
WP_004193869.1\|2917836_2919759_+	HAMP domain-containing protein	NA	NA	NA	NA
WP_004192421.1\|2919794_2920496_+	response regulator	NA	NA	NA	NA
WP_004193531.1\|2920642_2921419_+	exodeoxyribonuclease III	NA	NA	NA	NA
WP_004191998.1\|2921701_2923165_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004192209.1\|2923297_2924833_-	nitrogen regulation protein NR(I)	NA	NA	NA	NA
WP_004192981.1\|2924870_2926013_-	PAS domain-containing sensor histidine kinase	NA	NA	NA	NA
WP_004191998.1\|2926137_2927601_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004192601.1\|2927772_2929188_-	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_004191860.1\|2929592_2930057_+	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_004192990.1\|2930309_2931128_-	competence/damage-inducible protein A	NA	NA	NA	NA
WP_004193555.1\|2931124_2931958_-	EI24 domain-containing protein	NA	NA	NA	NA
WP_004192998.1\|2932501_2933491_-	sterol desaturase family protein	NA	NA	NA	NA
WP_004192001.1\|2933507_2934500_-	beta-propeller fold lactonase family protein	A0A2H4JCI3	uncultured_Caudovirales_phage	3.5e-11	59.6
WP_004202033.1\|2934601_2938729_-	ATP-dependent RNA helicase HrpA	A0A1V0SBU4	Catovirus	4.3e-47	28.5
WP_004192168.1\|2938752_2940129_+	amino-acid N-acetyltransferase	NA	NA	NA	NA
WP_004193961.1\|2940181_2940457_+	oxidative damage protection protein	NA	NA	NA	NA
WP_004192533.1\|2940629_2941961_-	MHS family MFS transporter	NA	NA	NA	NA
WP_038796647.1\|2942169_2943705_-	CoA transferase	NA	NA	NA	NA
WP_004206369.1\|2943701_2945495_-	isovaleryl-CoA dehydrogenase	NA	NA	NA	NA
WP_004193679.1\|2945603_2946506_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_038802950.1\|2948343_2949464_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004191758.1\|2950017_2951106_+	porin	NA	NA	NA	NA
WP_004193987.1\|2951574_2951913_-	P-II family nitrogen regulator	NA	NA	NA	NA
WP_004198600.1\|2951973_2953674_-	NAD+ synthase	A0A2L0UZF5	Agrobacterium_phage	5.8e-91	36.8
WP_004192390.1\|2953794_2954973_+	N-acetyltransferase	NA	NA	NA	NA
WP_011807749.1\|2955593_2955983_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_038796551.1\|2955961_2956867_+	GIY-YIG nuclease family protein	W8W2G4	Invertebrate_iridovirus	2.1e-07	43.1
WP_004192356.1\|2956925_2957453_-	inorganic diphosphatase	A0A2H4J8U1	uncultured_Caudovirales_phage	9.0e-51	53.8
WP_004193515.1\|2957613_2959053_+	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_004192728.1\|2959141_2959900_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_004192161.1\|2959938_2961246_+	MFS transporter	NA	NA	NA	NA
WP_004193604.1\|2961426_2962617_-	heme biosynthesis protein HemY	NA	NA	NA	NA
WP_004193146.1\|2962621_2964601_-	fused uroporphyrinogen-III synthase HemD/membrane protein HemX	NA	NA	NA	NA
WP_004193185.1\|2964600_2965590_-	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_004199404.1\|2965624_2965804_-	hypothetical protein	NA	NA	NA	NA
WP_004191560.1\|2965916_2968901_+	phosphoenolpyruvate carboxylase	NA	NA	NA	NA
WP_011203959.1\|2969046_2970510_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	2.6e-79	38.3

DBSCAN-SWA_7

3200974 : 3265192

Streptococcus_phage(27.78%)

tRNA,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004191998.1\|3200974_3202438_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004189921.1\|3202548_3203520_-	thymidylate synthase	A0A1V0DY05	Yersinia_phage	2.9e-47	36.1
WP_004189039.1\|3203576_3204962_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_004195958.1\|3204923_3205220_+	hypothetical protein	NA	NA	NA	NA
WP_004189413.1\|3205460_3205697_-	hypothetical protein	NA	NA	NA	NA
WP_004189886.1\|3206009_3206195_+	hypothetical protein	NA	NA	NA	NA
WP_011807762.1\|3206191_3207127_+	hypothetical protein	NA	NA	NA	NA
WP_162486048.1\|3207367_3209209_+	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_004189313.1\|3209416_3209920_+	dihydrofolate reductase	A0A0A0PL85	Bacillus_phage	9.6e-26	40.4
WP_004191998.1\|3210048_3211512_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004188997.1\|3211648_3213019_-\|protease	metalloprotease PmbA	NA	NA	NA	NA
WP_004195962.1\|3213164_3213773_+	ribosome-associated protein	NA	NA	NA	NA
WP_004195963.1\|3213789_3214374_+	molybdopterin adenylyltransferase	NA	NA	NA	NA
WP_004189767.1\|3214621_3215227_-	oligoribonuclease	Q8B5Y0	Diachasmimorpha_longicaudata_entomopoxvirus	4.2e-28	40.4
WP_004189931.1\|3215345_3216611_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_004189924.1\|3216607_3217552_+	ribosome small subunit-dependent GTPase A	NA	NA	NA	NA
WP_004189573.1\|3217620_3217938_+	lipoprotein	NA	NA	NA	NA
WP_004195964.1\|3218104_3219043_-	CobD/CbiB family protein	NA	NA	NA	NA
WP_004189888.1\|3219143_3219797_-	CoA pyrophosphatase	NA	NA	NA	NA
WP_004190182.1\|3220750_3221341_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_004189360.1\|3221661_3222051_-	50S ribosomal protein L19	NA	NA	NA	NA
WP_004189914.1\|3222188_3222983_-\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_004195969.1\|3222984_3223674_-	ribosome maturation factor RimM	NA	NA	NA	NA
WP_004189402.1\|3223718_3223973_-	30S ribosomal protein S16	NA	NA	NA	NA
WP_004189308.1\|3225413_3225881_+	TM2 domain-containing protein	NA	NA	NA	NA
WP_004189906.1\|3225915_3227073_-	PA0069 family radical SAM protein	NA	NA	NA	NA
WP_004188962.1\|3227181_3227670_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_004189387.1\|3227817_3229104_+	D-amino acid dehydrogenase	NA	NA	NA	NA
WP_004189890.1\|3231119_3232055_-	electron transfer flavoprotein subunit alpha	NA	NA	NA	NA
WP_004189750.1\|3232070_3232820_-	electron transfer flavoprotein subunit beta/FixA family protein	NA	NA	NA	NA
WP_011807766.1\|3233046_3233841_-	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004189862.1\|3233914_3234568_-	ABC transporter permease	NA	NA	NA	NA
WP_004190044.1\|3234557_3235592_-	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.8e-34	39.1
WP_004190087.1\|3235900_3236743_+	alpha/beta hydrolase	A7XCB7	Tanapox_virus	7.2e-18	27.2
WP_004188957.1\|3237085_3238009_-	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	8.4e-44	36.5
WP_004195984.1\|3238187_3239483_+	lytic murein transglycosylase B	NA	NA	NA	NA
WP_004532363.1\|3239708_3240611_-	cysteine synthase CysM	A0A1X9I5F1	Streptococcus_phage	1.9e-53	39.9
WP_004189725.1\|3240934_3241252_-	competence protein ComE	NA	NA	NA	NA
WP_004190173.1\|3241323_3242316_-	ADP-glyceromanno-heptose 6-epimerase	R9S880	Prochlorococcus_phage	9.1e-28	30.9
WP_004200795.1\|3242374_3243361_-	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	8.8e-15	26.5
WP_004189214.1\|3243329_3244730_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	2.1e-78	38.3
WP_004188993.1\|3244850_3246020_-	lipopolysaccharide assembly protein LapB	NA	NA	NA	NA
WP_004195986.1\|3246072_3246366_-	LapA family protein	NA	NA	NA	NA
WP_004191998.1\|3246601_3248065_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004189865.1\|3248183_3248507_-	integration host factor subunit beta	A7KV42	Bacillus_phage	4.7e-10	38.9
WP_004189285.1\|3248529_3250242_-	30S ribosomal protein S1	NA	NA	NA	NA
WP_004189396.1\|3250386_3251073_-	(d)CMP kinase	NA	NA	NA	NA
WP_096325444.1\|3251093_3253316_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_004190098.1\|3253519_3254602_-	prephenate dehydratase	NA	NA	NA	NA
WP_004189993.1\|3254636_3255719_-	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	8.5e-88	47.2
WP_004189806.1\|3255892_3256489_-	DUF2059 domain-containing protein	NA	NA	NA	NA
WP_004189243.1\|3256587_3259188_-	DNA gyrase subunit A	A0A172JHV7	Bacillus_phage	9.5e-101	29.8
WP_004189892.1\|3259698_3260373_+	OmpA family protein	NA	NA	NA	NA
WP_004532296.1\|3260541_3261240_+	bifunctional 3-demethylubiquinone 3-O-methyltransferase/2-octaprenyl-6-hydroxy phenol methylase	NA	NA	NA	NA
WP_004190123.1\|3261265_3261991_+	phosphoglycolate phosphatase	NA	NA	NA	NA
WP_144410474.1\|3262588_3263709_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.3e-48	39.1
WP_004186184.1\|3263971_3265192_+\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	6.6e-238	99.0

DBSCAN-SWA_8

3298934 : 3337105

Leptospira_phage(30.0%)

tRNA,integrase,transposase

attL 3309302:3309361|attR 3335938:3337134

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004186184.1\|3298934_3300155_+\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	6.6e-238	99.0
WP_004190100.1\|3300496_3300757_+	hypothetical protein	NA	NA	NA	NA
WP_004197792.1\|3300779_3301256_+	hypothetical protein	NA	NA	NA	NA
WP_004197793.1\|3301511_3301727_-	hypothetical protein	NA	NA	NA	NA
WP_004197795.1\|3302426_3302678_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_004203540.1\|3302964_3303453_-	hypothetical protein	NA	NA	NA	NA
WP_004189437.1\|3303449_3304700_-	exo-alpha-sialidase	NA	NA	NA	NA
WP_004188913.1\|3304708_3307045_-	TonB-dependent receptor	NA	NA	NA	NA
WP_004189159.1\|3307191_3307581_-	DUF2946 domain-containing protein	NA	NA	NA	NA
WP_011203825.1\|3308193_3308787_+	chorismate mutase	NA	NA	NA	NA
WP_004197797.1\|3308783_3308942_-	glycosyl transferase family 2	NA	NA	NA	NA
3309302:3309361	attL	NA	NA	NA	NA
WP_038802950.1\|3309348_3310469_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004189968.1\|3310499_3311171_-\|integrase	integrase arm-type DNA-binding domain-containing protein	B7SYF8	Stenotrophomonas_phage	1.3e-46	46.1
WP_144410475.1\|3311884_3313005_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004200457.1\|3313287_3313776_-	hypothetical protein	NA	NA	NA	NA
WP_004191998.1\|3314077_3315541_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004186453.1\|3315663_3316644_-	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NA	NA	NA	NA
WP_004186190.1\|3316646_3317102_-	peptidylprolyl isomerase	NA	NA	NA	NA
WP_004185928.1\|3317240_3318077_+	JAB domain-containing protein	NA	NA	NA	NA
WP_004186391.1\|3318370_3318604_+	50S ribosomal protein L28	NA	NA	NA	NA
WP_004185395.1\|3318621_3318789_+	50S ribosomal protein L33	NA	NA	NA	NA
WP_004186553.1\|3318845_3320558_+	L-aspartate oxidase	NA	NA	NA	NA
WP_004185611.1\|3320749_3321634_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_004185886.1\|3321630_3322767_-	quinolinate synthase NadA	NA	NA	NA	NA
WP_004186237.1\|3322935_3324132_-	aminotransferase	NA	NA	NA	NA
WP_004186398.1\|3324328_3325681_-	mechanosensitive ion channel	NA	NA	NA	NA
WP_004186079.1\|3325692_3326955_-	RsmB/NOP family class I SAM-dependent RNA methyltransferase	NA	NA	NA	NA
WP_004185746.1\|3326951_3327614_-	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	1.6e-25	40.0
WP_004535897.1\|3327738_3328731_+	bifunctional riboflavin kinase/FAD synthetase	NA	NA	NA	NA
WP_004185348.1\|3328842_3331680_+\|tRNA	isoleucine--tRNA ligase	A0A1V0SJ93	Klosneuvirus	1.6e-80	26.0
WP_004186086.1\|3331679_3332180_+	lipoprotein signal peptidase	NA	NA	NA	NA
WP_004186216.1\|3332241_3333453_+	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	3.0e-41	31.9
WP_004186718.1\|3333516_3333963_+	dUTP diphosphatase	Q2NP83	Xanthomonas_phage	7.9e-48	64.4
WP_004185819.1\|3334051_3334834_-	membrane protein	NA	NA	NA	NA
WP_004185697.1\|3334998_3335745_-	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|3335984_3337105_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
3335938:3337134	attR	NA	NA	NA	NA

DBSCAN-SWA_9

3458323 : 3515901

Vibrio_phage(17.65%)

tRNA,portal,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004191998.1\|3458323_3459787_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004190029.1\|3459953_3460724_-	exodeoxyribonuclease III	R4TWA8	Phaeocystis_globosa_virus	3.4e-30	33.8
WP_004189747.1\|3460755_3461595_-	hypothetical protein	NA	NA	NA	NA
WP_004190092.1\|3461721_3463194_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_004189326.1\|3463196_3464687_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_004189769.1\|3464799_3465099_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_004189550.1\|3465464_3466508_+	rod shape-determining protein	NA	NA	NA	NA
WP_004189331.1\|3466627_3467701_+	rod shape-determining protein MreC	NA	NA	NA	NA
WP_004189260.1\|3467697_3468210_+	rod shape-determining protein MreD	NA	NA	NA	NA
WP_004189575.1\|3468393_3470802_+	penicillin-binding protein 2	NA	NA	NA	NA
WP_004189171.1\|3470813_3471962_+	rod shape-determining protein RodA	NA	NA	NA	NA
WP_004190168.1\|3472319_3473096_-	sel1 repeat family protein	NA	NA	NA	NA
WP_004189570.1\|3473092_3473878_-	2-dehydro-3-deoxyglucarate aldolase	NA	NA	NA	NA
WP_004189793.1\|3474299_3474752_-	6-carboxytetrahydropterin synthase QueD	A0A088FAL2	Vibrio_phage	7.6e-14	30.8
WP_004189241.1\|3474771_3475404_-	7-carboxy-7-deazaguanine synthase	R4TAH8	Halovirus	2.1e-06	30.9
WP_004190026.1\|3475497_3476232_-	7-cyano-7-deazaguanine synthase QueC	A0A1B0Z0B4	Vibrio_phage	1.6e-50	42.5
WP_004189647.1\|3476699_3477383_-	response regulator	NA	NA	NA	NA
WP_004189034.1\|3477383_3479792_-	PAS domain-containing sensor histidine kinase	NA	NA	NA	NA
WP_004188929.1\|3479793_3480384_-	DUF4390 domain-containing protein	NA	NA	NA	NA
WP_004189046.1\|3480380_3481790_-	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	NA	NA	NA	NA
WP_004189409.1\|3482167_3483025_-\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
WP_004189288.1\|3483134_3483770_-	LysE family translocator	NA	NA	NA	NA
WP_004200737.1\|3483890_3484874_-\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	1.3e-07	38.0
WP_004201745.1\|3484905_3485409_-	peptide deformylase	A0A067XQZ3	Caulobacter_phage	2.7e-12	34.3
WP_004190020.1\|3485637_3486828_+	DNA-protecting protein DprA	S6BFL3	Thermus_phage	2.0e-21	39.2
WP_004190199.1\|3486887_3487259_+	thioredoxin family protein	NA	NA	NA	NA
WP_004200734.1\|3487469_3490079_+	DNA topoisomerase III	A0A2P1ELA0	Moumouvirus	7.7e-18	25.7
WP_004189230.1\|3490300_3491356_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004188904.1\|3491805_3492822_+	D-2-hydroxyacid dehydrogenase family protein	NA	NA	NA	NA
WP_004189208.1\|3492942_3493812_-	patatin-like phospholipase family protein	NA	NA	NA	NA
WP_004200732.1\|3493849_3494254_-	PaaI family thioesterase	NA	NA	NA	NA
WP_004187628.1\|3494644_3495865_+\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	7.8e-239	99.5
WP_038802950.1\|3497181_3498301_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004200731.1\|3498353_3498836_+	DUF2778 domain-containing protein	NA	NA	NA	NA
WP_004188977.1\|3498832_3499117_+	hypothetical protein	NA	NA	NA	NA
WP_004200730.1\|3499189_3500281_-\|portal	phage portal protein	A4JWQ2	Burkholderia_virus	2.0e-193	92.3
WP_004200729.1\|3500679_3501090_+	hypothetical protein	NA	NA	NA	NA
WP_004189258.1\|3501226_3502102_-	N-carbamoylputrescine amidase	A7IVZ1	Paramecium_bursaria_Chlorella_virus	9.6e-74	47.3
WP_004190014.1\|3502112_3503225_-	histone deacetylase	A0A2K9KZC4	Tupanvirus	3.2e-37	30.8
WP_004201742.1\|3503253_3504348_-	polyamine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004189434.1\|3504490_3505459_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004189874.1\|3505561_3506131_+	periplasmic heavy metal sensor	NA	NA	NA	NA
WP_004189689.1\|3506723_3507272_+	hypothetical protein	NA	NA	NA	NA
WP_004189592.1\|3507535_3508984_+	RNA polymerase sigma factor RpoD/SigA	A0A2I7SAT0	Vibrio_phage	4.9e-30	33.5
WP_004200727.1\|3509002_3510616_-	glutamate--cysteine ligase	NA	NA	NA	NA
WP_004200726.1\|3510775_3511717_-	DNA-3-methyladenine glycosylase 2 family protein	NA	NA	NA	NA
WP_004190110.1\|3511713_3512808_-	bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	3.8e-19	37.4
WP_004197761.1\|3513209_3513626_+	lactoylglutathione lyase	NA	NA	NA	NA
WP_004197759.1\|3513849_3514404_-	YaeQ family protein	NA	NA	NA	NA
WP_038802950.1\|3514781_3515901_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP009643

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP009643_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009643_1

322624-322769

Orphan

Consensus_repeat	Method
GCAGAGGCGCCGCCGCCGGAATACCCGATCATCGGGATGCTCGATCGCCGAAG	PILER-CR
CGGAATGCCCGATCATCGGGATGC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NZ_CP009643_1

>merge|NZ_CP009643|1|322624-322769|PILER-CR,CRISPRCasFinder
TCGTCGGGATGCTCGATTGCCGCAGTCACCCTCCGCCGGGGCTCCGTCGTCGGAATGCCCGATCATCGGGATGCCTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGCCGGAATACCCGATCATCGGGATGCTCGATCGCCG

>NZ_CP009643|1|1|322624-322769|PILER-CR
TCGTCGGGATGCTCGATTGCCGCAGTCACCCTCCGCCGGGGCTCCGTCGTCGGAA	TGCCCGAT
CATCGGGATGCCTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGCCGGAAT	ACCCGATCA
TCGGGATGCTCGATCGCCG

>NZ_CP009643|1|1|322674-322759|CRISPRCasFinder
CGGAATGCCCGATCATCGGGATGC	CTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGC
CGGAATACCCGATCATCGGGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009643.1\|WP_004200705.1\|333230_333884_+\|SagB/ThcOx-family-dehydrogenase	unknown	unknown	gnl\|CDD\|380318
NZ_CP009643.1\|WP_004196918.1\|332109_332331_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009643.1\|WP_004188488.1\|316677_316875_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009643.1\|WP_011204701.1\|333951_334386_-\|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl\|CDD\|223149
NZ_CP009643.1\|WP_004187792.1\|330115_331948_+\|STAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|223732
NZ_CP009643.1\|WP_004529492.1\|324840_326682_+\|ribonucleotide-reductase-like-protein	unknown	unknown	gnl\|CDD\|180772
NZ_CP009643.1\|WP_004187216.1\|319143_321417_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|369639
NZ_CP009643.1\|WP_004187305.1\|329087_330119_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236122
NZ_CP009643.1\|WP_004205322.1\|315326_316262_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176109
NZ_CP009643.1\|WP_004196898.1\|313138_313579_+\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|176863
NZ_CP009643.1\|WP_004205325.1\|316934_318833_+\|GMC-family-oxidoreductase	unknown	unknown	gnl\|CDD\|225186
NZ_CP009643.1\|WP_011807545.1\|312564_313167_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009643.1\|WP_004188244.1\|334791_335922_-\|porin	unknown	unknown	gnl\|CDD\|238208
NZ_CP009643.1\|WP_004187710.1\|326756_328559_+\|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	unknown	unknown	gnl\|CDD\|225098
NZ_CP009643.1\|WP_004188282.1\|309604_310648_-\|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|223101
NZ_CP009643.1\|WP_004200699.1\|310653_311886_-\|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha	unknown	unknown	gnl\|CDD\|223997
NZ_CP009643.1\|WP_004188034.1\|323326_324592_+\|polyhydroxyalkanoate-depolymerase	unknown	unknown	gnl\|CDD\|130908
NZ_CP009643.1\|WP_004187137.1\|332327_332777_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341411
NZ_CP009643.1\|WP_004187469.1\|321549_321945_-\|conjugal-transfer-protein-TraR	unknown	unknown	gnl\|CDD\|224648
NZ_CP009643.1\|WP_004200700.1\|313913_315029_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378454

Protein	Function_ID	Function_description	E-value
NZ_CP009643.1\|WP_004200705.1\|333230_333884_+\|SagB/ThcOx-family-dehydrogenase	gnl\|CDD\|380318	cd02142, McbC_SagB-like_oxidoreductase, oxidase similar to the microcin B17 processing protein McbC. This family is the oxidase domain of NRPS (non-ribosomal peptide synthetase) and other systems that modify polypeptides by cyclizing a thioester to form a ring. These include EpoB, part of the epothilone biosynthesis pathway; TubD, part of the tubulysin biosynthesis pathway, MtsD, part of the myxothiozol biosynthesis pathway; IndC, part of the indigoidine biosynthesis pathway and TfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides.	6.31252e-20
NZ_CP009643.1\|WP_004188034.1\|323326_324592_+\|polyhydroxyalkanoate-depolymerase	gnl\|CDD\|130908	TIGR01849, unnamed_protein_product, polyhydroxyalkanoate depolymerase, intracellular. This model represents an intracellular depolymerase for polyhydroxyalkanoate (PHA), a carbon and energy storing polyester that accumulates in granules in many bacterial species when carbon sources are abundant but other nutrients are limiting. This family is named for PHAs generally, rather than polyhydroxybutyrate (PHB) specificially as in Ralstonia eutropha H16, to avoid overcalling chemical specificity in other species. Note that this family lacks the classic GXSXG lipase motif and instead shows weak similarity to some [Fatty acid and phospholipid metabolism, Degradation].	1.36366e-112
NZ_CP009643.1\|WP_011204701.1\|333951_334386_-\|Hsp20/alpha-crystallin-family-protein	gnl\|CDD\|223149	COG0071, IbpA, Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones].	2.04683e-32
NZ_CP009643.1\|WP_004187792.1\|330115_331948_+\|STAS-domain-containing-protein	gnl\|CDD\|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	2.60835e-107
NZ_CP009643.1\|WP_004205322.1\|315326_316262_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176109	cd08417, PBP2_Nitroaromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of dinitrotoluene and similar compounds, such as DntR, NahR, and LinR. The transcription of the genes encoding enzymes involved in such degradation is regulated and expression of these enzymes is enhanced by inducers, which are either an intermediate in the metabolic pathway or compounds to be degraded. Also included are related LysR-type regulators clustered together in phylogenetic trees, including NodD, ToxR, LeuO, SyrM, TdcA, and PnbR. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	7.67997e-62
NZ_CP009643.1\|WP_004187216.1\|319143_321417_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|369639	pfam07992, Pyr_redox_2, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.	7.15563e-57
NZ_CP009643.1\|WP_004187305.1\|329087_330119_+\|hypothetical-protein	gnl\|CDD\|236122	PRK07877, PRK07877, Rv1355c family protein.	5.74738e-30
NZ_CP009643.1\|WP_004187469.1\|321549_321945_-\|conjugal-transfer-protein-TraR	gnl\|CDD\|224648	COG1734, DksA, DnaK suppressor protein [Signal transduction mechanisms].	1.7869e-14
NZ_CP009643.1\|WP_004196898.1\|313138_313579_+\|SRPBCC-family-protein	gnl\|CDD\|176863	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins. The PYR/PYL/RCAR-like family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. PYR/PYL/RCAR plant proteins are receptors involved in signal transduction. They bind abscisic acid (ABA) and mediate its signaling. ABA is a vital plant hormone, which regulates plant growth, development, and response to environmental stresses. Upon binding ABA, these plant proteins interact with a type 2C protein phosphatase (PP2C), such as ABI1 and ABI2, and inhibit their activity. When ABA is bound, a loop (designated the gate/CL2 loop) closes over the ligand binding pocket, resulting in the weakening of the inactive PYL dimer and facilitating type 2C protein phosphatase binding. In the ABA:PYL1:ABI1 complex, the gate blocks substrate access to the phosphatase active site. A conserved Trp from PP2C inserts into PYL to lock the receptor in a closed formation. This group also contains Methylobacterium extorquens AM1 MxaD. The mxaD gene is located within the mxaFJGIR(S)ACKLDEHB cluster which encodes proteins involved in methanol oxidation. MxaD may participate in the periplasmic electron transport chain for oxidation of methanol. Mutants lacking MxaD exhibit a reduced growth on methanol, and a lower rate of respiration with methanol.	3.1145e-25
NZ_CP009643.1\|WP_004205325.1\|316934_318833_+\|GMC-family-oxidoreductase	gnl\|CDD\|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	1.20731e-34
NZ_CP009643.1\|WP_004188244.1\|334791_335922_-\|porin	gnl\|CDD\|238208	cd00342, gram_neg_porins, Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers are stabilized by hytrophillic clamping of Loop L2. Loop 3 bends into the pore, creating an elliptical constriction of about 7 x 11A, large enough to allow passage of a glucose molecule without steric hindrance. Removal of the C-terminal residue (usuallly F) destabilizes the trimer and removal of the 16th beta-sheet abolishes trimerization. Unlike typical membrane proteins, porins lack long hydrophobic stretches. Short turns are found at the smooth, periplasmic end, longer irregular loops are found at the rough, extracellular end. C-terminal residue forms salt bridge with N-terminus.	2.53339e-55
NZ_CP009643.1\|WP_004187710.1\|326756_328559_+\|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	gnl\|CDD\|225098	COG2187, COG2187, Uncharacterized protein conserved in bacteria [Function unknown].	9.00049e-75
NZ_CP009643.1\|WP_004529492.1\|324840_326682_+\|ribonucleotide-reductase-like-protein	gnl\|CDD\|180772	PRK06948, PRK06948, ribonucleotide reductase-like protein; Provisional.	0
NZ_CP009643.1\|WP_004200699.1\|310653_311886_-\|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha	gnl\|CDD\|223997	COG1071, AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion].	8.93075e-143
NZ_CP009643.1\|WP_004188282.1\|309604_310648_-\|alpha-ketoacid-dehydrogenase-subunit-beta	gnl\|CDD\|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	0
NZ_CP009643.1\|WP_004187137.1\|332327_332777_-\|CBS-domain-containing-protein	gnl\|CDD\|341411	cd17775, CBS_pair_bact_arch, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains present in bacteria and archaea. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	1.39507e-50
NZ_CP009643.1\|WP_004200700.1\|313913_315029_-\|hypothetical-protein	gnl\|CDD\|378454	pfam10604, Polyketide_cyc2, Polyketide cyclase / dehydrase and lipid transport. This family contains polyketide cylcases/dehydrases which are enzymes involved in polyketide synthesis. It also includes other proteins of the START superfamily.	2.16274e-11

>NZ_CP009643.1|WP_004187469.1|321549_321945_-|conjugal-transfer-protein-TraR
MAAFDEHQLQVLGALLRACRQALQADVRAGERQRADEPYANLAGPAPDEGDEANADLFVDVDHALLGMKLAELRDVDAALQRIARRDYGCCADCGQPIAYERLLARPTALRCAPCQRAHERRFATQPRPSL
>NZ_CP009643.1|WP_004187216.1|319143_321417_-|FAD-dependent-oxidoreductase
MREFDYLLVGGGIASVTAARTLRGEDASASIAILCGEPVLPYQRPPLSQEWLMGAVQPASITLHDAAFYAAQRIDIALGVRAEQLDRAKRIVRTSSGATFRYGKLLIATGASAKAPALPGFGLDGVHVLHTFAQAQALKDAAAHARRATVLGGGFLGVEIAATLQALGLQVTLVERAPGVMPSLRAPALGGHFEALCRARGIDVLTRCEVRRVLGAQCVEAVETSDGGTRPCDLFVAAVGVTPNCGWLDGSGLALGDGVEVDAFLQTADPDVFAAGDVAHFDDPIFGVRRRIEHWDNAVRQGRIAARNMLGHRLPYRDVSIFYGSVFGLSYNLLGYPVGATETIERGAFDEASYMQLYLADDVLRAAFTIDRPAVEIAALNDAIRLHVNVAAHKMKLSDPNYPLDKLPVQTILILQGGGALGAFECGAVKALEQHGVRPDVISAVSIGAFNGAIVASHPKGATKALEAFWRELSIALPLPYESQWREAWLSSYVLSFGVPNFLKPQWSQLGFDADRLRAKWTSFFDATAIEQLIARYVDFDSLGMSPTRLLIGAVDVETGEPRIFDSYVDRLSPAHVLASGSLPPGMPWTVVDGRPYWDGGVVSNSPLDLVIARCGQIGGRVFIVDLFSGSKALPTNLVEVMLRREEIAYMDRVRNDLRFEEYASDFRDLVDGILAHVDAPSANEIRQQPLYIRLMGNRAAIDIARITLNREGRLSFIEDYDFSSDAIAQLQQQGYDAALVALANGRSRRRRGRRRA
>NZ_CP009643.1|WP_004205325.1|316934_318833_+|GMC-family-oxidoreductase
MLGATRSTLWGSRERPRIAAARAPGAAAIRMREEARECAGPRGAGRAPHRATAAGGKTGRRTVRAPSRARAGSNNQKVNRMKQQSYDYDYVVVGSGFGGSVSALRLSEKGYRVLVIEQGRRWTPENLPESTWNLSRWQWRPALGLHGFFSMRFFRHVVVLHGNAVGGGSITYANTLLVPPNKVWREGTWAGLEDWERVMPAHYATAKRMLGVVTNRRMDAADFRLKDMAKLIGVEKSFYPTEVGVFFGDDADAPGTRYADPYFGGAGPERTSCIGCGGCMVGCRHGAKNTLDRNYLYLAERLGAQVREQTKVVDVRPLDARADGAAGYAVEAVSLAAGARGAKSRLTCRGVVFAASSLGTQDLLMRLKEKGSLPRLSDALGKRVRTNAESLIGVRFPKSRVDLSKGVAIGSGIYIDEHTHIEATRYPSGSDTMGLLTTVLTRGAPGGLRVLVWLGALAKLVLTRPLSAWRMIDPRGFARETMIFLCMQTLEGHLTMRLKRRWFWPFSKQLATSGAKIPAYIPAANDFAQKAARALGGVPMTSLTEILLNVPMTAHCMGGAAMARDARDGVCDGRSRVFGYRNMYVCDGSVLGANLGVNPSLTITALAEHAMSHVPAAREQRWDSTAETPVAA
>NZ_CP009643.1|WP_004188488.1|316677_316875_+|hypothetical-protein
MAQTPIGAAGAISPSTARSIFLEIGLALAGRPIQVRRNRAPFTHGTPRRRPARGPTARTASPAPV
>NZ_CP009643.1|WP_004205322.1|315326_316262_+|LysR-family-transcriptional-regulator
MIQNLRQLDLNLLLVFDALMQEQNLSRAAIRLHMSQPAVSNALTRLRQQLGEPLFTRTARGMTPTAQARTLYEPVRQALYLLQIGLGPQADFEPDTHHLFKLSMNDYGQTVLLPDLLAHIKSRAPNVMLSVQSDDAGSIPAQLTTGTLDLAIDYLHFDNPELCYEPLHEEHLVVIGRAGHPAFAGGLALRGYEESGHVSIQPRDRRGSPLEIVLGSARVRRVVHLQVPHYLTIPALVAKSDLLGTIPRRLAERFADVYALQIAPLPIDIAPIQVSLIWHRQQDAQPGLRWLREQVVLTHRAIIGCGEHAPA
>NZ_CP009643.1|WP_004200700.1|313913_315029_-|hypothetical-protein
MTQDVTVFRARYRASVHPRYNAWLHGGFVLAYGCAAIAFFLKDVARVSAVQWASVPAAFLLFNWLEFTVHRHVGHVKRRFGAMFYRRHTGDHHSFFANEQIAYREARDWRVILFPAWLIVVFSLGLFALHAVLGRFDANVAGLFASTMLGGYLLYECVHACEHLPDAHPLAKWPWIRQMRVLHRVHHRDALMRSCNFDVIWPLMDWLHGTLRWSEAPGADMSTRMRHEIDIACAGADVLAYASDASRWPEWHPSSLRVDGPAGSLAAGSRFDEDVRAAGRVDRLHWDVVRNEPGVMWQARAANTAGSLRILLTYECSGGPRGARFVRTLHYHSPNPLLRLANALVMRGRVERESAYSLTLLKRRLEAARDA
>NZ_CP009643.1|WP_004196898.1|313138_313579_+|SRPBCC-family-protein
MKQQRIEIAEEFDAPVHQVFRFFSEHENLKSIFSPAKIRRISDGEPARNGVGSAREMRVPGAPPFVETVTAYQENELIEYRITRGSPLRDHLGVMRFVPIDERRTYFHYVITFEGKVPFVAPVVRHVLEGSIRRGLGKVATRRLWG
>NZ_CP009643.1|WP_011807545.1|312564_313167_+|hypothetical-protein
MNSILAPDNAPPASATRTSPLMSVLARAVVTAPLPGSGRAAEASTRVSTMRAQSASAIRIRSCRRSRSSRHGLPESPACRRKSPARPRSRRAPRPLADHTRMRFSPPRLGVRTARPPPAGRSKPARGASAIRLRVQRRSSRLTMTLINVIVIARAPQTAIVTHRGIGPRAIGRLTARRRAARPSTLETRPSYETATHRNR
>NZ_CP009643.1|WP_004200699.1|310653_311886_-|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha
MSQYGPLRLHVPEPTGRPGCKTDFSYLRLSPAGKVRKPPIDVAPADTSDLAYGLVRVLDEHGRAVGPWAPDLDPDILRKGIRAMLKTRIFDARMQIAQRQKKISFYMQCLGEEAIAVAHTLALERGDMCFPTYRQQGILMVREYPLVDMMCQLMSNERDPLKGRQLPVMYSTRDAGFFSISGNLATQFIQAVGWAMASAIKGDTRIASAWIGDGATAEADFHTALTFAHVYRAPVILNVVNNQWAISTFQAIAGGEGATFAGRGVGCGIASLRVDGNDFLAVYAASRWAAERARRNLGPTLIEWVTYRAGPHSTSDDPTKYRPGDDWTNFPLGDPLERLKRHMIGIGVWSEQDHEDTKAALEAEVLAAQKEAERYGMLADEHVPNVASIFEDVYKEMPAHLRRQRQQLGV
>NZ_CP009643.1|WP_004188282.1|309604_310648_-|alpha-ketoacid-dehydrogenase-subunit-beta
MTTASKEGPAASPMTMIQALRSAMDVMLERDGNVVVFGQDVGYFGGVFRCTEGLQNKYGKSRVFDAPINEGGIVGAAVGMGAYGLRPVCEIQFADYFYPASDQIVSEAARLRYRSAAEFIAPLTIRMPCGGGIYGGQTHSQSPEAMFTQVCGLRTVMPSNPYDAKGLLISAIENDDPVIFLEPKRLYNGPFDGHHERPVTPWSKHPASLVPDGYYTVPLDSAAIVRAGGDVTVLTYGTTVHVSLAAAEETGIDAEVIDLRSLWPLDLDTIVESVRRTGRCVVVHEATRTCGFGAELIALVQEHCFHWLEAPVERVTGWDTPYPHAQEWAYFPGPNRVGDALRRAMEN
>NZ_CP009643.1|WP_004188034.1|323326_324592_+|polyhydroxyalkanoate-depolymerase
MLYAWLEAQREFFRACQPWAGAAQRAGAGARPAGWPTWGPMARAADAVPAPPPFAIASIEIDGAAVPVDECVVDDTPFCALRKFSRRLRGDAAARPAVFLCTPLAGHHAVMLRETVETILATRDVYVTDWRNARDVPPEAGAFGLDDYVCTLERFVAGAAGDGLHMMAVCQATVPALAAVALLAARDVHVTSVALLGGPVDTRSHPTLIDRFALEHDLDWFRRTAIDIVPPPYAGAGRRVYPGFIQHAAIIVAHPQRRASLESRYWTAWMTGDFAAAARCLREMNEYGAVLDMTERYFLDTIRVIFHERLLAQGRWSIGRRLVAPRRLTRTALCTIEGGRDDIAGAGQTHAAHALCDAVPDAVRERITEPDCDHYDLFLGPRWRRTIHPALDAFWTRAEAARAAAGEPRPTAERAERRIAH
>NZ_CP009643.1|WP_004529492.1|324840_326682_+|ribonucleotide-reductase-like-protein
MRTINKRTRTIAHADSFVRMIGDMDDQPICDAVFADRYALPGEHSRAQACARVARALALAEPMATRSGAARRFYRNLLNGAFGAGRIMARAGAAPDQTMASCFVHPIRAPAALTRFHPNLDEALDEARLALAMGADIGYDFSAIPPAGARPDADHPDSPGVCAALDRFDRIGTQAGERDGRRRAQLAVLRCDHPDLLAFAAAKHRHAGRHARWTTLELAVAATDAFMQAVEQDLPWTLRHTAPPRDAPGGALPGADGAWTYASVPARHVWREIVSAARDGAGPGLVFVDAIDAADPLRGRERIDATSPCGAQPLPPYGSAMLGAIDLSRFVRNPFGAGGEPRFDFAAFDTAVRIEVRLLDNALDVTRWPLAAHARESYQKRRIGVGVTGLADMLAMMRLRYDSPAAREMARYIASDLRHHAYAASAELAAERGAYPLCDRHAHLDALRAGPPLPHAVCHAIERDGLRHSHLTSFAPVIGVSLAFGDHCSPGIEPARAWIEHRPVRAGAAGAPGMRAENHAHRLFRSLRGERAALPDYFATDADVAPGERLAMRVALQPYVDAGIDNTLTLANHYSLEEVNALLFAAWRAKLKSVAIRRADLARDAQPSDDDGV
>NZ_CP009643.1|WP_004187710.1|326756_328559_+|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein
MTTGAVAARRLPRRGTARGRRAPSRAFTIHGGDEMRRSRPPKPAKPAAVRRRPHGAARAHAIRGNGPQRRAVRERAARRLSRDIDAALRRASTYPHPAGPIVRIETHLSVVYLVGRFAYKRLKPFDFGFANFTELAARRRACEAELALNRPLAAPIYLAAGPLVRRARGLRLFGAGAAVDHVVRMRRFDERMLFSRLLARGALDAADIDAAATRLAAYHLHAPRDIPRRAYGSARELRRQLDDMLAPLERALGAALPASLRAWCVRRCDELAAHLDARRADGYVRACHGDLHLNNVVKRGRDALMFDCIDFDDALRWIDVINDLSFLLMDLHAHDRAALAHRLLNRWLDETGDFAGLAALPLYVAYRALVRALVATMRAGGDAAARAARIERARRYVDVAAHAARARRPCLLLCHGYSGSGKSVASRALADVSGAIRLSSDSERKRARPFAAVDARPLPASAYTPQQIDAQYERLRALARDVLRAGYTALVDATFLSHARRARFFALARELGVPVYVLDFHASRACLERRVDARAAARDDRSDAGAAVLATQRASADPLDADERARTIGFDTDVPLATLRSAGYWRPVLDAARVDAQATR
>NZ_CP009643.1|WP_004187305.1|329087_330119_+|hypothetical-protein
METSPLKTTTPEAIPPFNPSASVEDKLRLAIHYAILAPSSHNTQPWRFMVGDGSVMLCADRLRALSVVDPYDRELLISCGAALLNLRVALSRFGFAYVIDMFPSPSDPDVIALVRLDPHGYHDESLVPLFDAILERVTTRTPYANEAVPCDVQRALVDAGAAEGAEIACVDAPHALDEIAELIADADRLQFADPRFRRELANWVHPRRHDDGMPAFAAGVPALLDFATPVVASAIRTFDLGGGLAAMHHKLVDGSPLIVGISTASDDRDAWVATGQALERVLLVAAAAGLTASYLNQPIEIDALRERLRPLLHVDAHPQLLLRIGRGPVVAHAPRRPLMDVVS
>NZ_CP009643.1|WP_004187792.1|330115_331948_+|STAS-domain-containing-protein
MTERERAARGRNDARRGGGDSGGDDEAWRRWLPGIATLRTYRRAWLARDLYAGVALTAVLVPVGMSYAQAAGLPVIAGLNASIAALVGYAIFGPSRILVLGPDSALAALIAGAIAPLAHGEPAHAVALAAALALMSGGFCVLAGLLKLGFVTDLLSKPIQYGYLNGLALTLIASQLPSLLGTVPLGGTFVDQVASLAATVAQGRIDFASLALGGGCLAGIALLRRVAPAWPGMLIAVAGASIVAAWLGAAPDAGGAHAHVAYAHVANAHVALVGSLAGTLPPLGLPSISLADASRLIAGALAIAMVSVADISVLSHVFAQHDGSETDRNQELCALGAANLLAGMLRGCAVSSSASRTPVALAAGARTQLTSLVAAACIALLLIAPTLLARVPLAALAAVVVYSANALVDVRAIVRLYRVRRGECAVSVLCFAGVVLLGVVPGILLAVGLSLLSFVWRAWHPYDAVLGRVEGMHGYHDVSRHPGATLTRGLVAFRWDAPLFHANATIFRDHVRDAIAEAGAPVRCVVIAAEPITDVDVTAADMLATLRDELAARRIALVFAEMKGPVKDRLRTYGLFEKIGADHFFPTVTDAIEHFTRMRKDVATARRARR
>NZ_CP009643.1|WP_004196918.1|332109_332331_-|hypothetical-protein
MTDAVVSSRLAPCCVYIDIQGEGDVDVDAEGNGNGNIDVIDSKRCEPSGVEPVERAVRRPRYRAQSGCLSGIH
>NZ_CP009643.1|WP_004187137.1|332327_332777_-|CBS-domain-containing-protein
MNAAEICTREVVACRRTDTVLDAAHLMRDRHVGDLIVVDDAGHAHAPVGMLTDRDIVLSLIAKEVDPAALFVGEIMSAPAAVVHEHDSLWTIAQRMRLTGVRRMPVVNADGALVGMVSVDDLLASVAALFDEIASISRRQIHFEEKARD
>NZ_CP009643.1|WP_004200705.1|333230_333884_+|SagB/ThcOx-family-dehydrogenase
MSDPELLTYQPIAVALPGPAEAGAPAVIDLPPPDLGAGLPLMSALSLRASTREFSSAALAPTTLGELLWAADGVNRPTTGGRTAPSAHAFNEIDIYAALPDGVYRYDAALHRLLLKHAVDARNLTGYQDFVGAAPLDLIYVVRMSRLLSMPKPLRETFSAVAAGAIAQNVALYCASTGLGCVVRGWINHRLLAEALSLNEDELPILAQTVGKPAAHP
>NZ_CP009643.1|WP_011204701.1|333951_334386_-|Hsp20/alpha-crystallin-family-protein
MSNVTRYDPFSLEPVSDLFRGLFRPLRGIADADDEKLASMKIDVTENDQAYAVKAELPGVDKNDINVQIDGNTVSISAKVERNKELKEGERVIRRERYSGEFARTFSLANELDRDAASAQYQDGVLSLTLPKKASSEKKKLTIG
>NZ_CP009643.1|WP_004188244.1|334791_335922_-|porin
MMNAKSIAAAALAVAQAGLAHAQSSVTLYGALDAGVLWQNTSAASFSPTAPNTGAVVRFKDGGVYSSLWGIKGTEDLGGGYRVNFRLQGAFDGGTGKFGLSDAPGAVAAFNQIATLGVSGPFGTFNAGRQIVPMIYAMADTDVRAARFFGSVLTAWLGLNTAAGWPGNSTNAPIGALYDSDALVYQSPAFGGASLALEYAPGGVPGGVQRGARASIVLKYASNALNLAAVYYNGHDTNPAPGASATGLDNNRFVYVGAQYKLKDVAVSASYGNGRNPARGDRVNLDMFAFGLGYRVSPFFRVSSGVYYLKDRNRSANRSTSIVLGADYELSKHTTLYAQGGRVDNRGTMAQMLAYGQPVAPGLATTAAMLGMRHSF

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Crispr_ID: NZ_CP009643_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009643_2

555095-555187

Orphan

Consensus_repeat	Method
TCGCCGCCGCGCGCGACGACGCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP009643_2

>merge|NZ_CP009643|2|555095-555187|CRISPRCasFinder
TCGCCGCCGCGCGCGACGACGCGCTGAAGGACGCGCTCGCGCAGGCCGCCGCCGAGCGCGAGCGGCTGATCGCCGCCGCGCGCGCCGACGCGC

>NZ_CP009643|2|2|555095-555187|CRISPRCasFinder
TCGCCGCCGCGCGCGACGACGCGC	TGAAGGACGCGCTCGCGCAGGCCGCCGCCGAGCGCGAGCGGCTGA
TCGCCGCCGCGCGCGCCGACGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009643.1\|WP_004187376.1\|563328_565164_-\|response-regulator	unknown	unknown	gnl\|CDD\|237425
NZ_CP009643.1\|WP_004188525.1\|565313_566438_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223912
NZ_CP009643.1\|WP_004187423.1\|550862_551120_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009643.1\|WP_004201694.1\|553621_553930_+\|membrane-protein	unknown	unknown	gnl\|CDD\|274462
NZ_CP009643.1\|WP_044302747.1\|561368_562973_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|185008
NZ_CP009643.1\|WP_004187158.1\|560357_560867_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009643.1\|WP_004187346.1\|553926_554628_+\|F0F1-ATP-synthase-subunit-A	unknown	unknown	gnl\|CDD\|237383
NZ_CP009643.1\|WP_004198322.1\|559796_560300_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009643.1\|WP_004188840.1\|548937_550731_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|213656
NZ_CP009643.1\|WP_004188438.1\|553137_553629_+\|AtpZ/AtpI-family-protein	unknown	unknown	gnl\|CDD\|378198
NZ_CP009643.1\|WP_004188458.1\|546348_547527_-\|acetate/propionate-family-kinase	unknown	unknown	gnl\|CDD\|235922
NZ_CP009643.1\|WP_004188073.1\|551091_552696_+\|F0F1-ATP-synthase-subunit-beta	unknown	unknown	gnl\|CDD\|183615
NZ_CP009643.1\|WP_004188594.1\|547523_548927_-\|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase	unknown	unknown	gnl\|CDD\|236180
NZ_CP009643.1\|WP_004198321.1\|558694_559720_+\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|176257
NZ_CP009643.1\|WP_004188303.1\|557631_558480_+\|F0F1-ATP-synthase-subunit-gamma	unknown	unknown	gnl\|CDD\|376304
NZ_CP009643.1\|WP_004188537.1\|570718_572245_-\|efflux-transporter-outer-membrane-subunit	unknown	unknown	gnl\|CDD\|182103
NZ_CP009643.1\|WP_011807573.1\|554624_554876_+\|F0F1-ATP-synthase-subunit-C	unknown	unknown	gnl\|CDD\|184067
NZ_CP009643.1\|WP_004188221.1\|552685_553141_+\|F0F1-ATP-synthase-subunit-epsilon	unknown	unknown	gnl\|CDD\|184057
NZ_CP009643.1\|WP_004188355.1\|555622_557635_+\|F0F1-ATP-synthase-subunit-alpha	unknown	unknown	gnl\|CDD\|183987
NZ_CP009643.1\|WP_004188377.1\|566440_569656_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054

Protein	Function_ID	Function_description	E-value
NZ_CP009643.1\|WP_004187376.1\|563328_565164_-\|response-regulator	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	2.51413e-132
NZ_CP009643.1\|WP_004188525.1\|565313_566438_-\|ABC-transporter-permease	gnl\|CDD\|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	6.54035e-26
NZ_CP009643.1\|WP_004201694.1\|553621_553930_+\|membrane-protein	gnl\|CDD\|274462	TIGR03165, F1F0_chp_2, F1/F0 ATPase, Methanosarcina type, subunit 2. Members of this protein family are uncharacterized, highly hydrophobic proteins encoded in the middle of apparent F1/F0 ATPase operons. We note, however, that this protein is both broadly and sparsely distributed. It is found in about only about two percent of microbial genomes sequenced, with the first ten examples found coming from the Euryarchaeota, Chlorobia, Betaproteobacteria, Deltaproteobacteria, and Planctomycetes. In most of these species, surrounding operon appears to represent a second F1/F0 ATPase system, and the member proteins belong to subfamilies with the same phylogenetic distribution as the current protein family.	3.23546e-10
NZ_CP009643.1\|WP_004187346.1\|553926_554628_+\|F0F1-ATP-synthase-subunit-A	gnl\|CDD\|237383	PRK13421, PRK13421, F0F1 ATP synthase subunit A; Provisional.	1.54059e-122
NZ_CP009643.1\|WP_044302747.1\|561368_562973_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|185008	PRK15048, PRK15048, methyl-accepting chemotaxis protein II; Provisional.	2.56608e-79
NZ_CP009643.1\|WP_004188840.1\|548937_550731_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|213656	TIGR01838, Poly-beta-hydroxybutyrate_polymerase, poly(R)-hydroxyalkanoic acid synthase, class I. This model represents the class I subfamily of poly(R)-hydroxyalkanoate synthases, which polymerizes hydroxyacyl-CoAs with three to five carbons in the hydroxyacyl backbone into aliphatic esters termed poly(R)-hydroxyalkanoic acids. These polymers accumulate as carbon and energy storage inclusions in many species and can amount to 90 percent of the dry weight of cell. [Fatty acid and phospholipid metabolism, Biosynthesis].	6.3979e-179
NZ_CP009643.1\|WP_004188438.1\|553137_553629_+\|AtpZ/AtpI-family-protein	gnl\|CDD\|378198	pfam09527, ATPase_gene1, Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter. This model represents a protein found encoded in F1F0-ATPase operons in several genomes, including Methanosarcina barkeri (archaeal) and Chlorobium tepidum (bacterial). It is a small protein (about 100 amino acids) with long hydrophobic stretches and is presumed to be a subunit of the enzyme. It carries two transmembrane helices and is a magnesium or calcium uniporter. The atp operon of alkaliphilic Bacillus pseudofirmus OF4, as in most prokaryotes, contains the eight structural genes for the F-ATPase (ATP synthase), which are preceded by an atpI gene that encodes a membrane protein with 2 TMSs. A tenth gene, atpZ, has been found in this operon, which is upstream of and overlapping with atpI.	7.77353e-17
NZ_CP009643.1\|WP_004188458.1\|546348_547527_-\|acetate/propionate-family-kinase	gnl\|CDD\|235922	PRK07058, PRK07058, acetate/propionate family kinase.	0
NZ_CP009643.1\|WP_004188073.1\|551091_552696_+\|F0F1-ATP-synthase-subunit-beta	gnl\|CDD\|183615	PRK12597, PRK12597, F0F1 ATP synthase subunit beta; Provisional.	0
NZ_CP009643.1\|WP_004188594.1\|547523_548927_-\|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase	gnl\|CDD\|236180	PRK08190, PRK08190, bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated.	0
NZ_CP009643.1\|WP_004198321.1\|558694_559720_+\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|176257	cd08297, CAD3, Cinnamyl alcohol dehydrogenases (CAD). These alcohol dehydrogenases are related to the cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Cinnamyl alcohol dehydrogenases (CAD) reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0
NZ_CP009643.1\|WP_004188303.1\|557631_558480_+\|F0F1-ATP-synthase-subunit-gamma	gnl\|CDD\|376304	pfam00231, ATP-synt, ATP synthase.	1.10329e-32
NZ_CP009643.1\|WP_004188537.1\|570718_572245_-\|efflux-transporter-outer-membrane-subunit	gnl\|CDD\|182103	PRK09837, PRK09837, Cu(I)/Ag(I) efflux RND transporter outer membrane protein.	7.30998e-99
NZ_CP009643.1\|WP_011807573.1\|554624_554876_+\|F0F1-ATP-synthase-subunit-C	gnl\|CDD\|184067	PRK13468, PRK13468, F0F1 ATP synthase subunit C; Provisional.	3.27869e-35
NZ_CP009643.1\|WP_004188221.1\|552685_553141_+\|F0F1-ATP-synthase-subunit-epsilon	gnl\|CDD\|184057	PRK13447, PRK13447, F0F1 ATP synthase subunit epsilon; Provisional.	4.44077e-63
NZ_CP009643.1\|WP_004188355.1\|555622_557635_+\|F0F1-ATP-synthase-subunit-alpha	gnl\|CDD\|183987	PRK13343, PRK13343, F0F1 ATP synthase subunit alpha; Provisional.	0
NZ_CP009643.1\|WP_004188377.1\|566440_569656_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.59115e-92

>NZ_CP009643.1|WP_011807573.1|554624_554876_+|F0F1-ATP-synthase-subunit-C
MNNLIEVVSIAAAALAVSFGAIGPALAEGRAVGAAMDAIARQPDASGTVSRTLFVGLAMIETMAIYCLVVALLLLLFANPFVK
>NZ_CP009643.1|WP_004187346.1|553926_554628_+|F0F1-ATP-synthase-subunit-A
MNASPLSTVPLFSVGPVGISAPVLATWAIMAVLVALALVARRRLSVDAPSRLQSVLELFVATVDAQIADTMQTPPARYRALIGTIFVLVFCANGASLVPGVEPPTAHLETDAALALVVLAATLYYGVRARGVRGYLATFAEPTWVMIPLNVVEQLTRTFSLIVRLFGNVMSGVFVIGIVLSLAGLFVPIPLMALDLLTGTVQAYIFMVLSMVFIGAAVSGDETSAPRRGQENT
>NZ_CP009643.1|WP_004201694.1|553621_553930_+|membrane-protein
MIEMWETARASFDGIAAAIGLALGFAAGACHFVSLGWNSRLFVAGRAGVALALQFARVALAVAVLVVLARAGFGMLVAGSAGFFAARAIAVRRAAALTGARR
>NZ_CP009643.1|WP_004188438.1|553137_553629_+|AtpZ/AtpI-family-protein
MMKRRPPEVKREARDDAARGDARHAGAGAAPDDPRGAARRDPSPGSRAARGGATHPAARAAEPAAPKPAADRVERAAHTAAARAARGARDPEPSLGRRLAQIGVLGWTIVAPTLAALALGRWLDRMFATRVFFSAPLLMLGAALGLWLAWRWMKAQQHGDRDD
>NZ_CP009643.1|WP_004188221.1|552685_553141_+|F0F1-ATP-synthase-subunit-epsilon
MGAELRVTIATPARVCVDDLPIVSLRAEDASGAFGIRAGHVDFVTLLRASVVRWRTADGATHYAALDGGVLRVTRGARIEIACRDAVLGESLAELEAVVRGVRATQLDEKRRARVDETRLHAQAVRRLLTYLRPEHAKDGVHAPLKPETLE
>NZ_CP009643.1|WP_004188073.1|551091_552696_+|F0F1-ATP-synthase-subunit-beta
MADPQATNGTGAVCAERDASDVGDVSDVGDARDEGAGRVVAVRGAVVDVAFDGGALPALNEALTIPVDGAAPILAEVHAHLSDAAVRALALGPTGGLRRGAAVRATGGPIRVPVGDAVLGRLLSVTGAPGDDGAALAADVERRPIHRGAPLLAEQKSANALFATGIKVIDLLAPLAQGGKAAMFGGAGVGKTVFVMELIHAMVERYRGISVFAGIGERSREGHEMLLDMRGSGVLGRTVLVYGQMNEPPGARWRVPLTALAIAEYFRDERAQNVLLLMDNVFRFVQAGAEVSGLLGRLPSRVGYQPTLASEVAALQERIASVEGAAVTAIEAVYVPADDFTDPAVTAIAAHVDSMVVLSRAMAAEGMYPAIDPVASSSILLDPLVVGEAHVEVAIEVRRVIEHYRELQDVIALLGIDELGADDRRLVGRARRLQRFLTQPFAVTEAFTGQAGASVEIADTIAGCRAILRGDCDDWRESSLYMVGTLDDARRKEAAAREADARREAAAAASGAGPGTTSDPASGSAEPQGARHGR
>NZ_CP009643.1|WP_004187423.1|550862_551120_-|hypothetical-protein
MPFVACGSATVAPVWLVRRWLHHNGARRPPADLGQETGNRQTKRGIAQSETIDASASGADKVRAASIVDSNQIPQTYAWLQWPCQ
>NZ_CP009643.1|WP_004188840.1|548937_550731_-|alpha/beta-fold-hydrolase
MDTRHAPESGAPDAPLPAHPPASYAPESPYRIFDLAKEASVAKLTSGLSPASLQLALADWLIHLAAAPGKRAELATLALRHAALLGQYLLEAATGRTPAAPAQPSPGDRRFRAGAWQLEPYRFWHQSFLLAEQWWRAATRDVPGVSPHHEDVVAFSARQMLDTFAPANYVATNPEIAQRTALTGGANLAQGVWNYLDDVRRLITKQPPAGAEQFELGRNLATTPGRVVFRNHLIELLQYSPTTPDVYAQPVLIVPAWIMKYYILDLSAHNSLIRYLVGEGHTVFCISWRNVDASDRDLSLDDYRKLGVMDALDTIGAIVPGEKIHATGYCLGGTLLSIAAAAMANTGDDRLASITLLAAQTDFAEPGELQLFIDDSEIHFLESMMWERGYLGAHQMAGSFQLLMSNDLIWSRVIHDYLLGERTPMIDLMAWNADSTRMPYRMHSEYLRHLFLDNDLATNRYVIDGQTVSVHNIRAPFFVVGTEHDHIAPWRSVYKIHYLSGSDVTFVLTAGGHNAGIVSEPGHAKRHYRMKMTAAAAPSISPDEWLAGATDFEGSWWPAWHAWLARHSSPQRVAPPPLGKPGAHTLGDAPGTYVFQK
>NZ_CP009643.1|WP_004188594.1|547523_548927_-|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase
MDREILQNRPFDSLAIGDSASLVRTASRDDIDLFAAMSGDVNPAHLDAAFAAHDLFGHVVVHGMWTGALVSAVLGTKLPGPGTIYLDQTLEFRHPVAPGDTITATVTVAEKRPEKRIVLLDTRCTNQDGHVVLRGTATVIAPDTPITWERVPGPEVAVRRHDRYETFVRDAREQPPLRTAIVHPCSPDALRAAIDARDANLIEPILIGPQAKIRAIADAAGVDLAGVPIEAVEHSHAAAARAVEMGGAGEVAALMKGSLHTDELLAAVIGPASRLRTERRISHVYAMDVPAYPKPLLITDAAINIAPTLEQKRDICQNAVDLLHVLGVERPRVAVLAAVETVNPKMPSTLDAAALTVMAARGQIAGAIVDGPLAFDNAVSAVAAMSKGIASPVAGDADVLLVPDLEAGNMLAKQLMYFAGADAAGLVLGTRLPIILTSRADSLRVRIASAALAKLVAERTRAGALAS
>NZ_CP009643.1|WP_004188458.1|546348_547527_-|acetate/propionate-family-kinase
MSEPLLLTFNAGSSTLKIGLYSVANGEPAPLGRGKIDFNRAPLQFEYANGGEAHAVPLAAPVTDDLHAVLDEALGWIDAHLSVHELVSVGHRVVHGGDTFDGPVRIDERTLDAIAALVPLAPLHQPQSVRLIRALRHVRPHLPQVASFDTAFHRTQSDLVRRFALPRALFDAGIKRYGFHGLSYRYVAGRLRERHPSIARGKVVAAHLGSGASLCALDAGVSRDTSMGFSTLDGIPMATRCGALDAGVVLHLQKTLGRTLDDVEQMLYHRSGLLGVSGVSGDARALLADPSAGARDALELFAFRIAGETARLAATLGGLDALVFTAGIGEHQPQTRAAVCERLRWLSVELDAHANARNAETVSRDGSRVAVLVVPTDEEQVIARDAASVLHA
>NZ_CP009643.1|WP_004188355.1|555622_557635_+|F0F1-ATP-synthase-subunit-alpha
MTPTPDAPAAADAATGAGWLARRRGALARVALAPIAQAIGRVERVADGIAFVSGLEDTMLNEVLRFEGGVTGFAHTLDEDLISVVLLDPDAGVRAQTAVARTGAVLEVPAGPQLLGRVVDPLGRPLDGGAPLDAAHTLPIERAAPAIIERDLVSEPLDTGVLIVDALFTIGRGQRELIIGDRATGKTSLAIDAIVNQRHSDVICVYVAIGQRASAVRRVIDAVRRYGAPERCVFVVAPAACAPGLQWIAPFAGFSIAEYFRDRGQHALVVVDDLTKHAATHRELALLTREPPGREAYPGDIFYVHARLLERAAKLSAALGGGSLSALPIAETDAGNLAAYIPTNLISITDGQIVLDSALFAANQRPAVDVGLSVSRVGGKAQHPALRAASGRLRLDYAQFLELEAFTRFGGLTDARLRAQITRGERIRALITQPRFRALRTLDEVVLLKALAAGTLDAMSPDLVAPLRERLPAWLDARIAALTPALAPPRDWLADDAALDALAESVGELIERIAADAARRATAGMPAEDAAGDIGGAFGGEQARGDADRDADHGANREVSREVSPEASREVSREVSREVSHEADRDAAADAARVAGRAPGRAEPDRAVPRAMPDGPPRAQADGDRASASRPPPDARGDAARTAPSPQGGADANVNADANVDAEAEARHKR
>NZ_CP009643.1|WP_004188303.1|557631_558480_+|F0F1-ATP-synthase-subunit-gamma
MSDKLAAIEARTDTARQLQTVIGAMQGVAAARAHEAQQRLPGIRASAATVGAAIGDALSAGARSGETAAGARAAPRARFVVVLCSEQGFVGAYNAQLIEHATRPGPSVSREYMMVGSRGAMLADAGGVPLVWRTPMAARADDVVHLANRITDALYAHLAKRGAQPVSIVHAMPGGAARLEVTERRLLPFDYARFDTAPRAQPPLVHLPPATLLAELAQAYVFVELCEAAMLAFAAENEARTRAMIAARESVERALGDLLQAYRIARQDEITADIVELAASGL
>NZ_CP009643.1|WP_004198321.1|558694_559720_+|alcohol-dehydrogenase-AdhP
MAQYMKAAVVHAFGEPLRIEEVPVPTPGAGQILVNVKASGVCHTDLHAADGDWPVKPTLPFIPGHEGVGFVAAVGEGVRHVKEGDRVGVPWLYTACGHCEYCQTGWETLCHEQQNTGYSVNGSYAEYVLADPNYVGHLPSNVAFDEIAPILCAGVTVYKGIRVTDTRPGQWIAISGIGGLGHVAVQYAKAMGLHVVAVDVAPQKLELARKLGATFVVDASKDDPAAVIQKEIGGVHGVLVTAVSRGAFAQALGMVRRGGTVSLNGLPPGDFPLPIFSTVLNGITVRGSIVGTRRDLQESLDFAAEGLVRAHIHRDKLEHINGVFSALREGKVDGRIVLTGQ
>NZ_CP009643.1|WP_004198322.1|559796_560300_+|hypothetical-protein
MRGAGRASPSRARRYENVSKEPNTHREAGAPVHRYRLQVRNMNGECRTYELRLSSLDDGYTLEIDEWLNFPDTHLGDVTPVHVSRPVQFAVPAHEFYRRRRAFRTELIESVAAALRAGEVVRMRDSPDEYPGGHAGNPWVNWIRADLRANPGGRPPPVGDDMQDLIH
>NZ_CP009643.1|WP_004187158.1|560357_560867_-|hypothetical-protein
MRRIYFLLPDADTARAIVDELLLKRIEWRHIHVVANDRVPLENLPEASIAQSSDLLPALARGTAADGVTGALAGLAAIAFPPAGLTIAGGAVVAFAIAGAGFGAWVSTMIGVSVPNTRLKHFEDAVDNGELLMMIDVHRDRVEEIEALVKQHHPNAHLEGTDPTIPAFP
>NZ_CP009643.1|WP_044302747.1|561368_562973_+|methyl-accepting-chemotaxis-protein
MAPFHRRTTRNARTPTLSFRQKLWLPLVISLIALLLVSISSAWLSYQTRMEERRNDLTNVAHVGLSIVREYAALAQRGVLTDAQARKEALERLRSVRYGSDGYFIVIDSSPRMIMHPIKPDTVGKDLRHVADADGRHHYLTFASVAQSPQGGFVDYVFAHPNAHPAKAVDKLGYVIRYAPWDWIISTGAYIDDIQAAFAKSLCLSAGVFALLAALLALSVVYTNRGIERMIGGDPRIAAHMAGVIASGDLATPFATRREDRSSLMFAISQMRDALANAVAQIRASAGYVATTAGEIADSNMDLSSHTECQATALQQAASSMQRLTERVRDTADRARAASELAGSAARITDRGGDMVVRVVAAMNDIRAESRKMVDIIGVIEGIAFQTNILALNAAVEAARAGNEGRGFAVVASEVRVLAQRSASAAKDIRALIGRAAERVGNGAELVEATGATIGEAQHAICRVTGIVQDIAAAATDQSQGLEQINAAVSQMDSVTRRNATLVEHAAIAAQSLNEQSRCLQDAVAAFRTEALGC
>NZ_CP009643.1|WP_004187376.1|563328_565164_-|response-regulator
MHVEVFAQHPSCPGWHGEMARRIRAFDWSATELGPLERWPASLVAAVRTVLASPVPLVMLWGASGYMLYNDAYAAFAGGRHPYLLGQPVELGWPEVADFNRNVMRTCLAGGALSYRDKALVLLRNGRPEEVWMDLYYSPLAGDDGAPAGVLAVVVETTERVLAARHRDRAKAALHETNAELRRLTETLEQRVADAITERASIEEQLRQAQKMEAIGSLTGGIAHDFNNVLQVVSSNLQMLSAELGEDARAQRRIASAANAVARGAQLASHLLAFARRQPLAPAVLDPRGLIDGMREMLHRALGESVHVDADLRDDVWNVLADRHQFENALLNLAINARDAMRGEGTLKITACNIVLEAGRHARRNGLPPGEYVAFDIADNGVGMTPDILERVFEPFFTTKPDGQGTGLGLSMVFGFVKQSGGHTSIESAPGRGTTVRLLLPRCREAPAGEPAAQRRLPAEGGRETILVVEDDADVRLAVVDMLAQLGYKVITASDGEAGLLALESGAPIDLLFTDVIMPGRIKGGELARRAAQRVPPVPVLFTSGYTRDEIFHAGRLDPGVMLLGKPYRRDELAHKVRSVLDAHASARRAHGARHAQADPRAKTAAARVQR
>NZ_CP009643.1|WP_004188525.1|565313_566438_-|ABC-transporter-permease
MRRLAIIYRLGVKELWSLVRDPILLVLIAYTFTASIYSAATARPDTLHMAPIAIIDEDASPLSARIASAFFPPQFALPRMVTLAEADRGMDAGDFTFALDIPPNFQRDVLAGRPAQIQLNVDATRMSQAFTGNGYVQQIVSGEIDDFARRYRANTAPPVDIAMHMRFNPNLDQTWFGSLMEVINNVTLLSMVLTGAALIREREHGTIEHLLVMPVTPGEIMLAKVWSMGLVVACAAAFSLAFVVRGALHVPIEGSVALFVIGMAIHLFATTSMGIFLATLVRSMPQFGMLLVLVLLPLQLLSGSLTPRESMPFAVQNIMLAAPTTHFVEIGQAILYRGAGIETVWRQFLILAVIGTALFLLSLKRFRKTIGQMA
>NZ_CP009643.1|WP_004188377.1|566440_569656_-|ATP-binding-cassette-domain-containing-protein
MSAPSVVRFSDVSLRYGKTVALERITLEIPAGLTIGLIGPDGVGKSSLLALAAGARALQTGAVDALGGDMRSRRHRERVCRRIAYMPQGLGKNLYPTLSVEENLQFFARLFGHDADERRRRIDALTRSTGLFAFLSRPAGKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLARAQFWDLIARIRSERPAMSVIVATAYMDEAQRFDWLIAMDAGRVLATGAPAELLARTGCDSLEAAFIALLPEDERRGHKPVTLEPLRADAQTGTAIEARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPATEGTAQLFGKTVDPKDINTRRRVGYMSQAFSLYSELTVRQNLVLHARLFGVPAAEIDARVDEMARRFGLADIYDMLPDSLPLGMRQRLSLAVAMVHKPELLILDEPTSGVDPVARDSFWQLMIDLARRDRVTIFISTHFMNEAQRCDRISLMHAGRVLASDAPAALVRARGAATLEEAFIGYLVDASAQEAQEAQGGAGERPGAGERAAGESVAGRGAATDGDADGAHARPAAYANGAAQHRAPDADAAGTDVAAETGARDDARTAHAAGHSAGNDVRATVGSEVGSEVASEAGLAASAESGSERGVAHGAERAREPAADAGAAIDVEPGASAESATAAVAPARHAESAATSPRAGNAPAGTPFAAAPAEPPHRAFSAQRALSYMWREMLELRRDPVRATLALIGSLVLMCVIGIGISLDVEDLTYAVLDRDQTELSHDYALNLSGSRYFVERPPIADYAALDRRMRDGELSLAIEIPPNFARDVERGAPAQIGMWIDGAMPQRAETIRGYAIGMHTMWLADKARHRLGVTLAPRAEVVTRYRYNPDVKSLPAMIPAVMPLLLLMLPAMLTALAVVRERELGSILNLYVTPVTRTEFLIGKQVPYVVLAMLNFLLMTMLARIAFDVPVKGSFMTLLLAVLIFNVVATGIGLLASTFTRSQVAAIVMTIIGTMIPTVQFAGLLTPLSSLEGTGRLIGLVYPATYMLSISRGVFNKALSLHELYSQFWPLAACVPVILGATILLLKKQER
>NZ_CP009643.1|WP_004188537.1|570718_572245_-|efflux-transporter-outer-membrane-subunit
MTMRNDARHDERHQRRRGIARRAARHAAALALCAAVSGCLSLAPDYARKPPPVPAAYPAYPGEPGAGSRTLEQLGWRAYFVDPRLQALIETALANNRDLRIAAQRVEQARAAYGIRRADQYPTIAANAAYLRFREPGGLLLPSPIIGELYSASLSEVQWEIDFWGRVRSLKAAALDTFLASDASRRAVTVSLIGQVADAYLALCAYDERLALTNETIASRRDSLRIFRRRYEEGAISKLDLTQSEILLQQAQTLGSQLQQARDVQQHALDLLVGTNAAARTPASLDDASIAPDLAPGLPSELLANRPDVVAAEYQLRAAHANIGAARAAFFPRIALTSSIGTGSTELHNLFASGTAAWNFIPNLSVPIFDAGRNIGNLKLANARRDEALAQYEKTIQTAFRDVADALAARHWLADQVRIAQETLATQAERARLAKLRYDSGAARFLEVLDAQRDLLNAQQQLVQTRRALLASRVALYAALGGRLDEPARDGAAPRPSPEPSAKQGPLS

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Crispr_ID: NZ_CP009643_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP009643_3

1422171-1422333

Orphan

Consensus_repeat	Method
GGCGGGCCGGCCGCCG---------------------------CGCGGGCG	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP009643_3

>merge|NZ_CP009643|3|1422171-1422333|PILER-CR
GGCCGCTCGGCCGCCGCGCGGGCGCGTGTTCCACGTGGCGGCCTGCGCCGTGTCGGCCGCGGCGGCCGTGCGGAGCGGGCCGGCCGCCGCGGCGATGGTGGCCGCGCGGATCACGTGGATCACGTTGACGGCGTTGAACGGCGGGCCGGCCGCCGCGCGGGCG

>NZ_CP009643|3|2|1422171-1422333|PILER-CR
GGCCGCTCGGCCGCCGCGCGGGCG	CGTGTTCCACGTGGCGGCCTGCGCCGTGTCGGCCGCGGCGGCCGTGCGG
AGCGGGCCGGCCGCCGCGGCGATG	GTGGCCGCGCGGATCACGTGGATCACGTTGACGGCGTTGAACGGCGGG
CCGGCCGCCGCGCGGGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP009643.1\|WP_038709382.1\|1419226_1419712_-\|membrane-protein	unknown	unknown	gnl\|CDD\|377190
NZ_CP009643.1\|WP_004199609.1\|1435500_1436118_+\|GTP-cyclohydrolase-II	unknown	unknown	gnl\|CDD\|234745
NZ_CP009643.1\|WP_004184790.1\|1420794_1422150_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|163522
NZ_CP009643.1\|WP_004197880.1\|1420041_1420527_+\|YbaK/EbsC-family-protein	unknown	unknown	gnl\|CDD\|239824
NZ_CP009643.1\|WP_004199160.1\|1430369_1433471_+\|MMPL-family-transporter	unknown	unknown	gnl\|CDD\|169983
NZ_CP009643.1\|WP_004202576.1\|1435158_1435455_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009643.1\|WP_004197696.1\|1437808_1438489_+\|1,6-didemethyltoxoflavin-N1-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP009643.1\|WP_004197873.1\|1416112_1417498_-\|TolC-family-protein	unknown	unknown	gnl\|CDD\|224455
NZ_CP009643.1\|WP_004184766.1\|1409266_1410661_-\|heavy-metal-sensor-histidine-kinase-IrlS	unknown	unknown	gnl\|CDD\|273593
NZ_CP009643.1\|WP_004266238.1\|1433605_1435144_+\|efflux-transporter-outer-membrane-subunit	unknown	unknown	gnl\|CDD\|182103
NZ_CP009643.1\|WP_004184876.1\|1429275_1430373_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NZ_CP009643.1\|WP_004197868.1\|1410657_1411347_-\|heavy-metal-response-regulator-transcription-factor-IrlR	unknown	unknown	gnl\|CDD\|130454
NZ_CP009643.1\|WP_004197883.1\|1422449_1423058_+\|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl\|CDD\|223777
NZ_CP009643.1\|WP_004199157.1\|1428453_1429125_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|225222
NZ_CP009643.1\|WP_004524134.1\|1418415_1418556_-\|bacteriophage-protein	unknown	unknown	unknown
NZ_CP009643.1\|WP_004197875.1\|1417733_1418018_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP009643.1\|WP_004197872.1\|1414632_1416102_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273386
NZ_CP009643.1\|WP_004199606.1\|1423196_1425197_-\|ATP-dependent-zinc-metalloprotease-FtsH	unknown	unknown	gnl\|CDD\|273520
NZ_CP009643.1\|WP_004202583.1\|1411353_1414587_-\|CusA/CzcA-family-heavy-metal-efflux-RND-transporter	unknown	unknown	gnl\|CDD\|129992
NZ_CP009643.1\|WP_004197695.1\|1436114_1437812_+\|WD40-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|238121

Protein	Function_ID	Function_description	E-value
NZ_CP009643.1\|WP_004197873.1\|1416112_1417498_-\|TolC-family-protein	gnl\|CDD\|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	1.82633e-32
NZ_CP009643.1\|WP_004199609.1\|1435500_1436118_+\|GTP-cyclohydrolase-II	gnl\|CDD\|234745	PRK00393, ribA, GTP cyclohydrolase II RibA.	6.64755e-109
NZ_CP009643.1\|WP_004184790.1\|1420794_1422150_+\|amino-acid-permease	gnl\|CDD\|163522	TIGR03810, arginine-ornithine_antiporter, arginine-ornithine antiporter. Members of this protein family are the arginine/ornithine antiporter, ArcD. This exchanger of ornithine for arginine occurs in a system with arginine deiminase, ornithine carbamoyltransferase, and carbamate kinase, with together turn arginine to ornithine with the generation of ATP and release of CO2. [Transport and binding proteins, Amino acids, peptides and amines].	4.43391e-175
NZ_CP009643.1\|WP_004197880.1\|1420041_1420527_+\|YbaK/EbsC-family-protein	gnl\|CDD\|239824	cd04332, YbaK_like, YbaK-like. The YbaK family of deacylase domains includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze mischarged cysteinyl-tRNA(Pro)'s, thus helping ensure the fidelity of translation. Organisms whose ProRS lacks the INS domain express an INS homolog in trans (e.g. YbaK, ProX, or PrdX).	4.00352e-32
NZ_CP009643.1\|WP_004199160.1\|1430369_1433471_+\|MMPL-family-transporter	gnl\|CDD\|169983	PRK09579, PRK09579, multidrug efflux RND transporter permease subunit.	0
NZ_CP009643.1\|WP_004197696.1\|1437808_1438489_+\|1,6-didemethyltoxoflavin-N1-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	3.56047e-15
NZ_CP009643.1\|WP_038709382.1\|1419226_1419712_-\|membrane-protein	gnl\|CDD\|377190	pfam04008, Adenosine_kin, Adenosine specific kinase. The structure of a member of this family from the hyperthermophilic archaeon Pyrobaculum aerophilum contains a modified histidine residue which is interpreted as stable phosphorylation. In vitro binding studies confirmed that adenosine and AMP but not ADP or ATP bind to the protein.	4.09203e-108
NZ_CP009643.1\|WP_004184766.1\|1409266_1410661_-\|heavy-metal-sensor-histidine-kinase-IrlS	gnl\|CDD\|273593	TIGR01386, Probable_sensor_protein_PcoS, heavy metal sensor kinase. Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.	0
NZ_CP009643.1\|WP_004266238.1\|1433605_1435144_+\|efflux-transporter-outer-membrane-subunit	gnl\|CDD\|182103	PRK09837, PRK09837, Cu(I)/Ag(I) efflux RND transporter outer membrane protein.	5.59568e-111
NZ_CP009643.1\|WP_004184876.1\|1429275_1430373_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	9.65507e-71
NZ_CP009643.1\|WP_004197868.1\|1410657_1411347_-\|heavy-metal-response-regulator-transcription-factor-IrlR	gnl\|CDD\|130454	TIGR01387, Transcriptional_regulatory_protein_PcoR, heavy metal response regulator. Members of this family contain a response regulator receiver domain (pfam00072) and an associated transcriptional regulatory region (pfam00486). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc. Most members encoded by genes adjacent to genes for encoding a member of the heavy metal sensor histidine kinase family (TIGRFAMs:TIGR01386), its partner in the two-component response regulator system. [Regulatory functions, DNA interactions].	2.40938e-111
NZ_CP009643.1\|WP_004197883.1\|1422449_1423058_+\|rhomboid-family-intramembrane-serine-protease	gnl\|CDD\|223777	COG0705, COG0705, Membrane associated serine protease [Amino acid transport and metabolism].	8.96274e-30
NZ_CP009643.1\|WP_004197872.1\|1414632_1416102_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273386	TIGR00999, Nickel-cobalt-cadmium_resistance_protein_NccB, Membrane Fusion Protein cluster 2 (function with RND porters). [Transport and binding proteins, Other].	4.97736e-65
NZ_CP009643.1\|WP_004202583.1\|1411353_1414587_-\|CusA/CzcA-family-heavy-metal-efflux-RND-transporter	gnl\|CDD\|129992	TIGR00914, Nickel-cobalt-cadmium_resistance_protein_NccA, heavy metal efflux pump, CzcA family. This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds].	0
NZ_CP009643.1\|WP_004199606.1\|1423196_1425197_-\|ATP-dependent-zinc-metalloprotease-FtsH	gnl\|CDD\|273520	TIGR01241, ATP-dependent_zinc_metalloprotease_FtsH, ATP-dependent metalloprotease FtsH. HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_CP009643.1\|WP_004199157.1\|1428453_1429125_-\|transcriptional-regulator	gnl\|CDD\|225222	COG2345, COG2345, Predicted transcriptional regulator [Transcription].	5.95232e-60
NZ_CP009643.1\|WP_004197695.1\|1436114_1437812_+\|WD40-repeat-domain-containing-protein	gnl\|CDD\|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	3.31012e-39

>NZ_CP009643.1|WP_004184790.1|1420794_1422150_+|amino-acid-permease
MKHSVRHPFHPSTPLPASASAPLRAAAPRQLPFALLTALVIGSMIGSGIFSLPQNMASGAGAGAIVIGWAITGVGMLMLALVYQTLAHRKPELDNGVYAYAHASAGDFVGFNSAWGYWVSAWIGNVGYLVIVFGTLGYAFPAFGDGNTRAALAFQPHRFTTDFWGNVHLPGVLDQVKSTMLITVWVFIGIEGASVYSARAKNRDDVGRATIVGFVVVLLLLMAVSLLSLGIVSQPELAAMKNPSMAGVLEKAIGRTGVAIAGVGLLVSVGGALLAWTLLAAEAMFTPAKDGVMPAFLSRENAHGVPANALWATNGLVQLFLLVTLVSNATYQALISLATSMILVPYLFSAVYALVIAIKGEGYAPGEAVRVRDATIGAVATVYCGWLLYAAGPKYLLLSALLYAPGALLYAWAKRERGERPFKPFEAAILIALVAFASLAGWLVAAGRISL
>NZ_CP009643.1|WP_004197880.1|1420041_1420527_+|YbaK/EbsC-family-protein
MSMSVTLQECLRQKASRYEVIHHPYSHSNMEAAAAAHVPGDRLAKTVLLEDAQGYVAAVLPTTHAVRLSELWAKTGRHLVLAKEVELRELFKDCDVGALPPVCMAYGMQTFLDDSLARQPDVYFEAGDHEELVHMDRDEFLALMDKAERASFSHKIQGVVS
>NZ_CP009643.1|WP_038709382.1|1419226_1419712_-|membrane-protein
MQLLSVAIDKPDTANFILGQTHFIKSVEDIHEALVGAVPGIRFGLAFCEASGKRLVRHSGTGAALTELACRNALAIGAGHCFLVFLGDGFYPLNVLNAIKAVPEVCRIFCATANPTEVVVAQSDQGRSILGVVDGFSPLGIETDEDVRWRKDLLRNIGYKA
>NZ_CP009643.1|WP_004524134.1|1418415_1418556_-|bacteriophage-protein
MSLAAQDLIELLRLAQGGAGALTLHLLREIAGNLIAFGVADCRGGC
>NZ_CP009643.1|WP_004197875.1|1417733_1418018_-|hypothetical-protein
MKRATSLAFAALFALAASSAFAHGMPERVFKERKPIRADARQEPSQRDASSAGCASGCPAGAALSRQDDRASGASPSSVGVEAAAGVHPAVNGG
>NZ_CP009643.1|WP_004197873.1|1416112_1417498_-|TolC-family-protein
MPKRIFAALVSAAIAASAVQAQAQPAPAPSAPDGPAAAPPDARAASVSVTPAVSPAPISTSTVSVAPPALSLDDALALAAANNPLLKSARSSADASVGALVQAGARPNPTVSFLQEGFGRQERTTTAVVSQPIELGGKRRSRVDAASYGRESALASLDGRAAALRADVTGAFYGVLAAQRQLQVADESAAIAARSADMADKRARAGKVSPVEATKARVAQTAAQIELSNAQTRVAAALARLANATGSADVRGRAASGDLDALPAAEPLPQLLGRLDDAPLARAAKADMLRTNAQIAIERAKRVPDITVSAGVKHVVTGGAPDNQAVVGISIPLPLFDTNRGALLEAVHNAAKASADFDAERARLRLDLTQAYANYERATGEARRLKADVLPAARQSLDAMSRGYQLGKFGFLDVLDAQRTLFDAQSRYVQALADAHQSYADIERVVGAPARDASRPLAQLR
>NZ_CP009643.1|WP_004197872.1|1414632_1416102_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MQRKPLILAGAAAAGALAIVLALARAPSTSSAPAASGAAAAAPASGATGPHGGAMFAQGALSAEIVLSEKPDDARLVVYPFVDGKPVEQGAAVSATLTRHDGERVALQFAQAGAKYTSAQPIARPHVFDASIDVRIGARSASFPFSRADGAIALDDAQLGAARIGIARAGPAQIITSFQLPGEIKFNEDRTAHVVPRVAGIVERVAVSIGENVKPGQVLAVIASTDLADRRSELMTAERRLQAARTSYAREKTLWEERISAEQDYLQAQVQLREAEIAAANARQKLAALNASAASGALNRYELRAPFAGTIVEKHIAPGEAIAADANVFVVSDLSSVWAEMAVPAQRLNDVRVGRHATVSAAAFESKSSGPIAYVGALLGEQTRTAPARVVLPNPDGAWRPGMFVNVTVDAGAQNVPVAVESDALQDVDGAPAVFVRTPKGFVAQAIETGRRDERRVEIVKGLAPGQTYAAANSFVLKAELGKGVADEH
>NZ_CP009643.1|WP_004202583.1|1411353_1414587_-|CusA/CzcA-family-heavy-metal-efflux-RND-transporter
MFERLIRFAIAHRWLVMLAIVAAASLGVYSYQKLPIDAVPDITNVQVQVNTSAPGYSPLEAEQRITYPVETAMAGLPNLEQTRSISRYGLSQVTVIFKDGTDIYFARQLVNERIQEAKDKLPPGIAPAMGPTSTGLGEIYLWTVEADAGARKPDGTRYTSADLRELQDWVVRPQLRNVPGVTEVNSIGGYVKEYRVAPNPTKLMSYGLTLADVVRALERNNDNVGAGYIEKRGEQYLVRVPGQARSAEDIANIVLVNAGGVPVRMKDIGAVDLGRELRTGAATANGEEVVLGTVFMLMGENSRTVAKAVAARMADVNRTLPAGVRAIAVYDRTVLVEKAVRTVKKNLLEGAVLVIAVLFLFLGNIRAAVITALVIPLSMLMTFTGMVNAKVSANLMSLGALDFGIIVDGAVVIVENCIRRLAHAQQAAGRPLTRDERFAEVFAASQEARRALIFGQLIIMVVYLPIFALTGVEGKMFHPMAITVVMALAAAMALTVTFIPAAVALFIGRRVEEKENRLMSAAKRLYAPVLDAFVARPGQVLAGATAVVALSLVLATRLGSEFIPSLNEGDLAVSAQRIPGTSLTQSVAMQQSIEKTLKARFPEIDRVFARTGTAEIAADPMPPNLSDGYIMLKPADQWPDPRKSRDALRGEIEAVLAQLPGNAYEFSQPIQLRFNELISGVRSDVAVKIFGDDMATLNATGEQIAAALQKVPGASEVKVEQTTGLPVLTVNLDRDKLARYGVTVGDVQDTVAAAVGGRKAGLLFQGDRRFDIVVRLPDELRTDVEAIKRLPIALPLAAPAGASGPLAQAPYVPLAELATVDTSPGPNQISREDGKRRVVVSANVRGRDVGSFVADARERIASDVRVPAGYWLSWGGQFEQLQSASERLKIVVPLALAMVFVLLFVMFNNAKDGLLVFTGIPFALTGDVVSLWLRGIPLSITAAVGFIALSGVAVLNGLVMISFIRNLRDEGAPLDAAVREGALTRLRPVLMTALVASLGFLPMAFATGTGAEVQRPLATVVIGGILSSTALTLLVLPVLYRVAHAAPPRATLGARAAGWLARLAPAAVLRRRRESSR
>NZ_CP009643.1|WP_004197868.1|1410657_1411347_-|heavy-metal-response-regulator-transcription-factor-IrlR
MRILIVEDEPKTGMYLRKGLTEAGFIADWVEDGVTGLHQAETEEYDLIILDVMLPGHDGWTVLERLRRAHSTPVLFLTARDDVGDRVKGLELGADDYVVKPFDFVELVARVRSILRRGQARESTVLRIADLELDLTRRKATRQGDVVLLTAKEFALLWLLMRREGEILPRATIASQVWDMNFNSDTNVVDAAIRRLRSKIDDAYEPKLIHTVRGMGYVLEVRSASAPSR
>NZ_CP009643.1|WP_004184766.1|1409266_1410661_-|heavy-metal-sensor-histidine-kinase-IrlS
MIRRLLPRTLRARLTALIILSTAATLALSGVALYSALHNRLVGMSSYEMSATLAAMRTHLANVANVDDIPRKSDLWIDQLHGHQNLDLAIYDTDGRLRFATRGFVAPRPALGAPQTRVPASAAPAGATFSYLADDAPLRGGNPRTARIVVQYDGKNDHALLRAYAYTVVVIEVLAVVLTAALAYGIAMLGLSPLRRLVARAEQMSSSRLAQPLPELDTSGELKEMEHAFNAMLKRLDESFVRLSQFSSNLAHDMRTPLTNLLAEAQVALSKPRTADEYRDVIESSIDEYQRLSRMIEDMLFLARSDNAQSHLAIRTLDAAAQAERVAGYYEPMAEDAEVSIVVRGKAEVRADALLYHRALSNLISNALNHAPRGSTITIECAQAADAATISVSDTGRGIEAPHRERIFERFYRVDPARHNSASGTGLGLAIVRSIMENHGGTCGVDSEPHVRTTFWLKFPAHAA
>NZ_CP009643.1|WP_004197883.1|1422449_1423058_+|rhomboid-family-intramembrane-serine-protease
MTLAIVVLNVIGFLVELAAPERVLSLFALWPPRAGAGLPPAAAPAFHVWQLVTYSALHAGLSHLLFNMLGLVMFGRDVERALGRARFGTLYLASVVCGALTQLALARYSAAAAAPTIGASAGVFGVLAAYALLYPSRRVVLLIPPIPMRAWVFALLYAGGELLLGVAGAASGIAHFAHLGGMFGAIALMLAWGRPRSEWPVQ
>NZ_CP009643.1|WP_004199606.1|1423196_1425197_-|ATP-dependent-zinc-metalloprotease-FtsH
MKSETGYMGFVVVLVFMVLLALQLATLSAPATQIAYSDFRKLAAAAQLDDLEVSPTRITGVLRSASAAAALPASDAEAIKRAGTPWRFSTKRVTDERLIDTLAATGTRYRGADDDTWIGTLASWIVPIAVFALVWNLMLRRPRGGLQDWSGVGKSKPRVYVEAKTGIDFDDIAGIDEAKAELQQIVAFLRAPARYQRLGGKIPKGVLIVGAPGTGKTLLAKAVAGEAGVPFFSTSGSSFVEMFVGVGAARVRDLFEQAQQKAPCIIFIDELDALGKVRGAGLASGNDEREQTLNQLLVEMDGFQANSGVILMAATNRPEILDPALLRPGRFDRHIAIDRPDLTGRRQILSVHVKHVKLGPDVDLGELASHTPGFVGADLANIVNEAALHAAELDKPAIDMSDFDEAIDRAMTGMERKSRVMSEREKITIAHHEAGHALIAQTRAHSDPVKKVSIIPRGIAALGYTQQVPTEDRYVLRKSELLDRLDVLLGGRVAEEIVFGDVSTGAENDLERATEMARHMVARYGMSERIGLATFGDADTQGLSPLVWQRGGERCSESTATRIDDEIQRLLAEAHDRVSRTLKERRGALERIAGYLLEHEVVDHDKLVRLVNDEPTPEPGARDPGGDAAKRSGIGAAPAKPPAEVGSAELRDPARKADNADHSVPQ
>NZ_CP009643.1|WP_004199157.1|1428453_1429125_-|transcriptional-regulator
MDDNFSKQEIPVSERVLNVLKRRGPLQAAELGAYLGTTGEAARQQLKKLEAEGLVEAQNVPQGVGRPARIWRLTSLGHGHFPDAHADMTVDLIRIIRTTLGQPTLDLLIAARETEMRRTYAHTLAGVTDPEERIARLAELRDREGYFAEWSRAPDGDGWLFIENHCPICAAATACQGFCRSELEIFREMLGDALTIERIEHIPAGARRCAYRIRPSGAGAGGE
>NZ_CP009643.1|WP_004184876.1|1429275_1430373_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MGRRLLLALALLAFIFGGLFLWRESRVQAADHPPAPPAALTVSAVAVRAAPERVTLDAVGSLDAVRQVTLAPEVAGRVVALQFDAGSAVRKGQLIVQLFDEPERAKLASIQAKAAYAKRQLDRSQALAQTGAEPRNLFDRHRFDFDAAAADIRETQAVITQKAVRAPFDGVLGLRRVNLGQYLNAGDAIATLTDLDTLYANFTVPQKNLSQLRLGQSVSITTDAYPERTLVARVSAIEPQIGTDTRNVAVQATLPNPDHLLRPGMYIQARLELPPRERALTVPDTAVQTSQRGESVLVVGKPGRDGLGVVRLQPVRTGRRADGRIAIADGLRPGDVVVTSGQVRLAAGDRVKVALDDGAGSGAAQ
>NZ_CP009643.1|WP_004199160.1|1430369_1433471_+|MMPL-family-transporter
MNAGAPHDSGAARARFTDVFVRRPVLSLVFSLLILLVGLRALMSLPVRQYPALESATISVATDYPGASQELMQGFVTTPIAQSIATADGIEYITSTTTQGKSVVKARLRLNANADRAMTEVMAKVQQVKYKLPADAYDSVITKLTDAPTAVMYLGFASDALSIAQITDYVVRVAQPLVTTVPGVASAEILGGQNLAMRVWLDATRLAAHGLSAGDVAAAIRANNVQAAPGQVKGSLTIADISANTDLTDVGAFNEMVVKSAPNGGGLVRLKDVATVEIGGENYNSSALMNGRRAVYIAVNATPAGNPLEIVRGVGAVLPAIERNKPASVQIANMFDGARFVNASIAEVRSTLTEAIAIVVVVIFLFLGSFRAVIIPVLTIPLSLVGSAALMLAAGFSLNLLTLLAMVLAIGLVVDDAIVVVENIHRHIEQGEPPVRAALIGAREIASPVLVMMATLISVYAPIGLMGGLTGLLFKEFAFTLAGAVLVSGIVALTLSPMLGSLLLTSRMSEGRVAKAIERTLERVTHAYRRGLHASLAARPAILLIGAGVLAGIVLLFSGVKRELAPQEDQGSIMVAVKAPQYANLDYMERYAPDIERVFRTLPEADTSFILNSYGGSNLGFAGVNLVDWDKRTRSAAALQALIQARGDGIRGERVFAFQLPALPASSGGLPIQMVLRTPSGFADLYAQMERIKAAAQKSGLFAVLDSDLTFDSRAVGVTIDRNQANTLGVTMKDIADTLAVLVGENYVNRFNFKGRSYDVIPQVSRSERLSSEMLSRYYVKTGSGRMIPLSTVIQVTNGSQANALSQFNQMNAATFSAVPAPGVTMGDAVAFLEAQKLPAGFSIDWLGESRQYVQEGNRLAVTFGFALIVIFLVLAAQFESLRDPLVILVSVPLSICGALAPLYLGFATLNIYTQIGLVTLIGLISKHGILMVSFANDLQRHEGLDRRAAIERAAAVRLRPILMTTAAMVAGLVPLVFAAGAGAASRFAIGITVSTGMLVGTLFVLPTVYTFVAKDHGAAMRSERAQLLAATR
>NZ_CP009643.1|WP_004266238.1|1433605_1435144_+|efflux-transporter-outer-membrane-subunit
MRTAVRAAAVAAAFFAAGCTLAPRYERPAAPVSGAFPADGVYAAQPGAAPGARSANGQAAVDIGWREFFVDPRLQRLIEIALKNNRDLRVSVLNVEASRAQYQITRAGLFPTLSGTGTGTIQRTPAGVSITGQPLISRTYNVGVSASWELDLFGRVQSLKDQALAQYFATAQARKAAEISLVASVADQYLTLLSTDDLLQVTQNTLKSARASYDLTKLQFDNGTGSELDLRQAQTVVETALASQQAQARARAQALNALVLLIGEPLPDDLPADLPLNAQNLLTDIPAGLPSDLLTRRPDIMQAEETLRAANANIGAARAAFFPKISLTSAFGTASTTLGGLFKAGTAAWSFAPNIALPIFEGGQNIANLDLAHVQKRIEIANYEKAIQSAFREVSDGLAARGTYDQQIAALERNEHAQQRRYDLSDLRYRNGVDSYLSVLTAQTDLYSAQQQLISARLARWTNLVDLYRALGGGWLERAGETPRPADAPVDYGKAAPAPAASASARTAAVIG
>NZ_CP009643.1|WP_004202576.1|1435158_1435455_+|hypothetical-protein
MRQPNARQHSARRPSAARAGRERIGRTWRTKKKTDREMIGDTVIGTDAQSAMLLHNRTQQPIKSSPRTRETATNRKSIQAFDITIQKLPCSSRCVSQC
>NZ_CP009643.1|WP_004199609.1|1435500_1436118_+|GTP-cyclohydrolase-II
MSASVRTRVNVPIRPRTAQQRFDAEMVTFQGLCDSAEHLALVFGPLADAPLVRVHSECLTGDVFGSARCDCGEQLDESVAMFGREGGILLYLRQEGRGIGLYNKLDAYRLQISQGLDTFAANRALNFPDDLRDFRVAAQMLQALGVTEISLVTNNPDKVSQIEKHGIRIRRVLQTGVFVNTTNHGYLRAKIDHHRHAINLSQELQ
>NZ_CP009643.1|WP_004197695.1|1436114_1437812_+|WD40-repeat-domain-containing-protein
MITHRAPISGIAAHRDQYVLTAGYDNQVILWDAKTQRPLARAMHDHLANQGAFSPDGAYVVTSSSDYSARLWTVPDLRLVAVFADQEDDVEMSVFHPDKPLVATASRDHRVRVYDFGGKLLHTFSGHTADVISVEWMRGADEIVSSSDDGTIKRWSLANNGLVADIDLDGIETDTIAIAADGRIFAGNDEGEIISIGVDGARATIAAHDAGVKRLVLDGERGLLVSLSYDRTMRLWKVGAAGEPRALGGAALPPEVWPRSCSFEGDEHIVFSTFHSSYRRYNWKTERWDAAELPPTHGVNAVQPVDGHLWTIGDAGIVRVDQREHARTGSLCNFLAPAGELILTGGQLGKVFDARSGRELHQHRSPLNCGVAFARDGAAHAVIGTYTGEGIVLRIDGTRATHVADLPLHANAVKGIAISGDLIFSVAADASATWYRASTLEPAFELKRAHDKIANGCAGLGDGYFASVSRDLKLRIWSPDSHAEVIATPHTHSIKCVAASADGRYVATGSYNGRVAVYDRVETRWALDARVTTAGVSSLAYDPAARAFLASSYDGNVYRIPLERA
>NZ_CP009643.1|WP_004197696.1|1437808_1438489_+|1,6-didemethyltoxoflavin-N1-methyltransferase
MSAAEPHYIDAQRTIAPVDAPLAAPHEYAAVLRSDFVSSYHDGRDVWTDEAAMRPASAILHAHLGRPADVLDAGAGRGRDTAYFLEQGHRVTAVDLVEPPEWAQLAQRWGERVCFVARPVSELDGEARFDGALDNGCLHHQHPDAYRAYLARIHALLRPDGRFTISVFESDGPGRLYANHAQRLYREFTEPELAELLRAAHFTPVDSQRVPRPKAGLHYLRVGRDS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

23511 : 81220

Leptospira_phage(33.33%)

transposase,holin,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004190851.1\|23511_24501_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004196180.1\|24497_26360_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004190879.1\|26373_26805_-	GPW/gp25 family protein	NA	NA	NA	NA
WP_004196178.1\|26884_27412_-	type VI secretion protein	NA	NA	NA	NA
WP_004190846.1\|27555_29061_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004202234.1\|29063_29612_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004188491.1\|29645_30584_-	hypothetical protein	NA	NA	NA	NA
WP_096325460.1\|30706_31827_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004188420.1\|33532_35047_-	acetyl-CoA hydrolase/transferase family protein	NA	NA	NA	NA
WP_004188272.1\|35411_36101_+	CDP-alcohol phosphatidyltransferase family protein	NA	NA	NA	NA
WP_004206084.1\|36860_37862_+	HpnL family protein	NA	NA	NA	NA
WP_004188389.1\|37900_38668_+\|holin	phosphocholine cytidylyltransferase family protein	NA	NA	NA	NA
WP_004188554.1\|38664_40353_+	phosphoenolpyruvate mutase	NA	NA	NA	NA
WP_004187270.1\|41541_42609_+	2-aminoethylphosphonate aminotransferase	NA	NA	NA	NA
WP_004187801.1\|42754_43522_-	DJ-1/PfpI family protein	NA	NA	NA	NA
WP_004196021.1\|43594_44560_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_004187681.1\|44798_45872_+	FUSC family protein	NA	NA	NA	NA
WP_004188593.1\|46185_47397_-	multidrug effflux MFS transporter	NA	NA	NA	NA
WP_004196023.1\|47500_49003_+	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_004200655.1\|49190_50213_-	transglutaminase family protein	NA	NA	NA	NA
WP_004187774.1\|50203_52900_-	circularly permuted type 2 ATP-grasp protein	NA	NA	NA	NA
WP_004188267.1\|53039_56462_-	transglutaminase family protein	NA	NA	NA	NA
WP_004188464.1\|56598_57555_-	transglutaminase family protein	NA	NA	NA	NA
WP_004187979.1\|57563_58505_-	alpha-E domain-containing protein	NA	NA	NA	NA
WP_004551378.1\|58599_60015_-	circularly permuted type 2 ATP-grasp protein	NA	NA	NA	NA
WP_004188408.1\|60310_60517_-	hypothetical protein	NA	NA	NA	NA
WP_004188127.1\|60748_61372_+	nitroreductase	NA	NA	NA	NA
WP_004202249.1\|61446_61950_+	hypothetical protein	NA	NA	NA	NA
WP_004200658.1\|62507_63605_+	chitin-binding protein	C3TWS8	Euproctis_pseudoconspersa_nucleopolyhedrovirus	8.0e-25	33.3
WP_004187548.1\|63864_64428_+	peroxiredoxin	NA	NA	NA	NA
WP_004196027.1\|64631_65774_+	alkyl hydroperoxide reductase subunit F	NA	NA	NA	NA
WP_038802950.1\|65673_66793_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004187151.1\|67446_69462_-	cation acetate symporter	NA	NA	NA	NA
WP_004196029.1\|69455_69776_-	DUF4212 domain-containing protein	NA	NA	NA	NA
WP_004188376.1\|69932_71915_-	acetate--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	1.8e-83	44.8
WP_004202253.1\|73332_73941_+	TIGR00645 family protein	K4K6D8	Caulobacter_phage	5.4e-23	33.0
WP_004187501.1\|73980_75516_+	fumarate hydratase	NA	NA	NA	NA
WP_004188572.1\|75670_76147_+	bacterioferritin	NA	NA	NA	NA
WP_004187671.1\|76193_77066_+	glutamate racemase	NA	NA	NA	NA
WP_004187745.1\|77197_77437_+	bacterioferritin-associated ferredoxin	NA	NA	NA	NA
WP_004188251.1\|77661_78402_+	energy transducer TonB	NA	NA	NA	NA
WP_004188455.1\|78438_79167_+	MotA/TolQ/ExbB proton channel family protein	NA	NA	NA	NA
WP_004200660.1\|79180_79609_+	biopolymer transporter ExbD	NA	NA	NA	NA
WP_004191998.1\|79756_81220_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6

DBSCAN-SWA_2

192101 : 266189

Organic_Lake_phycodnavirus(25.0%)

transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004187303.1\|192101_193187_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004187986.1\|193186_195076_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004187068.1\|195106_195688_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_004187921.1\|195674_196640_-	ImpE/SciE family protein	NA	NA	NA	NA
WP_004188539.1\|196636_197383_-	TagK domain-containing protein	NA	NA	NA	NA
WP_004196243.1\|200847_201429_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004188012.1\|201463_202963_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004188308.1\|203079_203565_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_004187276.1\|203671_204175_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_004188743.1\|204196_205543_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004188530.1\|205631_206897_+	type VI secretion system protein TssL	NA	NA	NA	NA
WP_004188288.1\|211020_211251_+	hypothetical protein	NA	NA	NA	NA
WP_004196246.1\|211836_213183_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004187006.1\|213425_214352_-	catecholic dioxygenase	NA	NA	NA	NA
WP_004187502.1\|214406_215378_-	quinone oxidoreductase	NA	NA	NA	NA
WP_004187879.1\|215406_217275_-	asparagine synthase (glutamine-hydrolyzing)	F2Y1H0	Organic_Lake_phycodnavirus	3.0e-24	25.9
WP_004187705.1\|217320_218805_-	Pyoverdin chromophore biosynthetic protein pvcC	NA	NA	NA	NA
WP_004188574.1\|218830_219730_-	TauD/TfdA family dioxygenase	NA	NA	NA	NA
WP_004188150.1\|219726_220785_-	L-tyrosine/L-tryptophan isonitrile synthase family protein	NA	NA	NA	NA
WP_157047211.1\|220783_221161_+	hypothetical protein	NA	NA	NA	NA
WP_004188385.1\|221386_224347_-	glycoside hydrolase family 92 protein	NA	NA	NA	NA
WP_004196252.1\|224558_226475_-	hypothetical protein	NA	NA	NA	NA
WP_004187552.1\|226916_227282_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_004202300.1\|227421_227706_-	hypothetical protein	NA	NA	NA	NA
WP_004188660.1\|227725_228466_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_004188170.1\|229010_229943_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004204001.1\|230095_231343_+	D-amino acid dehydrogenase	NA	NA	NA	NA
WP_004554722.1\|231506_232406_+	glutamate/aspartate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004196262.1\|233017_233458_-	hypothetical protein	NA	NA	NA	NA
WP_004201242.1\|233949_234990_-	fatty acid desaturase	NA	NA	NA	NA
WP_004188790.1\|235283_236120_+	PhnD/SsuA/transferrin family substrate-binding protein	NA	NA	NA	NA
WP_004187366.1\|236461_237364_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004187422.1\|237543_238734_+	amidohydrolase	NA	NA	NA	NA
WP_004188653.1\|240121_240751_+	porin	NA	NA	NA	NA
WP_004203996.1\|240944_242342_+	ATP-dependent RNA helicase DbpA	A0A0N9Q9J4	Chrysochromulina_ericina_virus	2.3e-45	31.7
WP_096325434.1\|243481_244601_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004198864.1\|244646_245393_-	hypothetical protein	NA	NA	NA	NA
WP_004188578.1\|246779_247529_-	IclR family transcriptional regulator	NA	NA	NA	NA
WP_004188783.1\|247772_248678_+	CoA ester lyase	NA	NA	NA	NA
WP_004187664.1\|248993_250073_+	porin	NA	NA	NA	NA
WP_004187771.1\|250114_251593_+	MmgE/PrpD family protein	NA	NA	NA	NA
WP_004188039.1\|251669_252797_-	OpgC domain-containing protein	NA	NA	NA	NA
WP_004204611.1\|253196_254090_-	EamA family transporter RarD	NA	NA	NA	NA
WP_004187760.1\|254086_254383_-	acylphosphatase	NA	NA	NA	NA
WP_004202312.1\|254543_255551_+	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
WP_004188344.1\|255805_257260_+	hypothetical protein	NA	NA	NA	NA
WP_004188250.1\|257485_258670_-	glycosyltransferase	NA	NA	NA	NA
WP_004187484.1\|259063_260005_+	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NA	NA	NA	NA
WP_004187762.1\|260017_261178_+	adenosyl-hopene transferase HpnH	NA	NA	NA	NA
WP_004187860.1\|261522_261876_+	DOPA 4,5-dioxygenase family protein	NA	NA	NA	NA
WP_004200694.1\|262424_263783_+	aspartate aminotransferase family protein	NA	NA	NA	NA
WP_004191998.1\|264725_266189_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6

DBSCAN-SWA_3

694969 : 761735

Burkholderia_phage(16.67%)

tRNA,transposase,portal,integrase

attL 699334:699393|attR 762039:762586

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004190269.1\|694969_695974_+\|transposase	transposase	NA	NA	NA	NA
WP_004190833.1\|697971_699051_+	putative membrane protein	NA	NA	NA	NA
WP_038802950.1\|699116_700236_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
699334:699393	attL	NA	NA	NA	NA
WP_004190721.1\|700264_701152_-	hypothetical protein	NA	NA	NA	NA
WP_004195671.1\|701334_701661_-	hypothetical protein	NA	NA	NA	NA
WP_004190242.1\|701891_702740_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_004190802.1\|702835_703429_+	LysE family translocator	NA	NA	NA	NA
WP_004195676.1\|703670_704081_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004190743.1\|704333_705572_+	alpha-hydroxy-acid oxidizing protein	NA	NA	NA	NA
WP_004190434.1\|705636_706092_-	YbaK/EbsC family protein	NA	NA	NA	NA
WP_004190582.1\|707376_709020_+	DUF3459 domain-containing protein	NA	NA	NA	NA
WP_004190469.1\|709178_709808_-	thiamine phosphate synthase	NA	NA	NA	NA
WP_004190954.1\|709804_711145_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_004190659.1\|711230_712010_-	sensor histidine kinase	NA	NA	NA	NA
WP_004190540.1\|712102_713023_-	DMT family transporter	NA	NA	NA	NA
WP_004190343.1\|713089_713965_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004190990.1\|714062_714446_+	tautomerase family protein	NA	NA	NA	NA
WP_004195687.1\|714643_716566_+	CHAD domain-containing protein	NA	NA	NA	NA
WP_004190826.1\|716600_717449_+	TOBE domain-containing protein	NA	NA	NA	NA
WP_004190506.1\|717992_718694_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	2.9e-20	32.3
WP_004190258.1\|718695_719370_-	molybdate ABC transporter permease subunit	NA	NA	NA	NA
WP_004195689.1\|719382_720183_-	molybdate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004204469.1\|720623_721322_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_004190691.1\|721572_722721_+	PHB depolymerase family esterase	NA	NA	NA	NA
WP_004190391.1\|722817_722976_+	DUF3563 domain-containing protein	NA	NA	NA	NA
WP_004190960.1\|723088_723508_-	organic hydroperoxide resistance protein	NA	NA	NA	NA
WP_004190487.1\|723645_724098_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_038730270.1\|724217_724469_+	hypothetical protein	NA	NA	NA	NA
WP_004190835.1\|724600_725413_-	hypothetical protein	NA	NA	NA	NA
WP_004190439.1\|725403_726399_-	homoserine kinase	NA	NA	NA	NA
WP_004190726.1\|726492_726891_-	hypothetical protein	NA	NA	NA	NA
WP_004190957.1\|727046_728573_+	AMP nucleosidase	NA	NA	NA	NA
WP_004195697.1\|728656_729343_-\|integrase	tyrosine-type recombinase/integrase	E5E3N4	Burkholderia_phage	3.3e-93	81.6
WP_009950031.1\|729339_729627_-\|portal	phage portal protein	K4NZV0	Burkholderia_phage	6.4e-43	94.4
WP_004203322.1\|731968_732232_+	hypothetical protein	NA	NA	NA	NA
WP_004190352.1\|732667_733159_-	DUF523 domain-containing protein	NA	NA	NA	NA
WP_004190916.1\|733818_734103_-	hypothetical protein	NA	NA	NA	NA
WP_004190924.1\|734254_734524_-	hypothetical protein	NA	NA	NA	NA
WP_004530319.1\|734520_735270_-	TIGR00730 family Rossman fold protein	A0A1D8KUT5	Synechococcus_phage	5.6e-22	37.8
WP_004190446.1\|735271_738052_+	DNA polymerase I	S5M8J1	Bacillus_phage	2.9e-71	30.0
WP_004190401.1\|738370_739753_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_038763983.1\|740128_741922_-	membrane protein	NA	NA	NA	NA
WP_004204467.1\|742261_742483_+	hypothetical protein	NA	NA	NA	NA
WP_004190499.1\|742635_743511_+	dienelactone hydrolase family protein	NA	NA	NA	NA
WP_004190656.1\|743569_744439_-	sulfurtransferase	NA	NA	NA	NA
WP_045589192.1\|744563_746027_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004190814.1\|746179_747286_-	aromatic ring-hydroxylating dioxygenase subunit alpha	NA	NA	NA	NA
WP_004190549.1\|747555_747849_+	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_004190235.1\|747845_748730_+	(2E,6E)-farnesyl diphosphate synthase	NA	NA	NA	NA
WP_004266656.1\|748813_750718_+	1-deoxy-D-xylulose-5-phosphate synthase	NA	NA	NA	NA
WP_004195713.1\|750868_751678_+	GTP cyclohydrolase I FolE2	NA	NA	NA	NA
WP_011204325.1\|752068_753109_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	1.7e-93	53.1
WP_004190760.1\|753248_754472_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_004190342.1\|754551_754764_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_004190948.1\|754930_755377_+	GatB/YqeY domain-containing protein	A0A292GL36	Xanthomonas_phage	8.8e-23	48.6
WP_004190679.1\|755471_757346_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	4.9e-67	36.2
WP_004540553.1\|757392_757731_-	hypothetical protein	NA	NA	NA	NA
WP_004190933.1\|757789_759832_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	4.2e-35	32.0
WP_004191998.1\|760271_761735_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
762039:762586	attR	NA	NA	NA	NA

DBSCAN-SWA_4

817334 : 867024

Leptospira_phage(25.0%)

transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004190585.1\|817334_818738_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004190689.1\|818753_820070_+	DotU family type VI secretion system protein	NA	NA	NA	NA
WP_004190681.1\|820072_823702_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_004190273.1\|824598_824826_-	hypothetical protein	NA	NA	NA	NA
WP_011807597.1\|824824_827413_+	protein kinase	M1I231	Acanthocystis_turfacea_Chlorella_virus	2.5e-08	27.0
WP_004190988.1\|827465_828545_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_004190671.1\|828607_829186_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004190849.1\|829178_830687_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004190698.1\|830746_831238_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_004196148.1\|831256_831817_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_004190509.1\|831821_833693_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004190820.1\|833689_835168_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004190714.1\|835146_837801_+	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	2.3e-78	30.8
WP_004203275.1\|837797_840002_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	9.6e-46	29.9
WP_045589201.1\|840076_840730_+	hypothetical protein	NA	NA	NA	NA
WP_162486055.1\|840659_841742_+	RHS repeat protein	NA	NA	NA	NA
WP_038802950.1\|841752_842873_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_045589205.1\|842772_843534_-	acyltransferase family protein	NA	NA	NA	NA
WP_011204340.1\|843546_844527_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004190776.1\|845043_846468_+	cytosine permease	NA	NA	NA	NA
WP_004190245.1\|846464_847403_+	NAD-dependent protein deacetylase	S5M4R0	Bacillus_phage	1.4e-14	25.3
WP_004190461.1\|847365_848043_+	DUF938 domain-containing protein	NA	NA	NA	NA
WP_004190588.1\|848366_848510_-	hypothetical protein	NA	NA	NA	NA
WP_004190614.1\|848498_849914_+	NADP-dependent phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	2.1e-41	30.2
WP_011204342.1\|850112_850445_+	DUF4148 domain-containing protein	NA	NA	NA	NA
WP_004190911.1\|850889_851201_+	cupin domain-containing protein	NA	NA	NA	NA
WP_011204344.1\|851479_852244_+	peptidoglycan DD-metalloendopeptidase family protein	NA	NA	NA	NA
WP_004190805.1\|852374_853010_-	hypothetical protein	NA	NA	NA	NA
WP_004190603.1\|853278_853815_+	cytochrome b	NA	NA	NA	NA
WP_004190837.1\|853975_854371_+	DUF2946 domain-containing protein	NA	NA	NA	NA
WP_045589206.1\|854458_856696_+	TonB-dependent copper receptor	NA	NA	NA	NA
WP_004196164.1\|857046_858072_+	triacylglycerol lipase	NA	NA	NA	NA
WP_004190433.1\|858116_859151_+	lipase secretion chaperone	NA	NA	NA	NA
WP_004200631.1\|859252_860782_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_004190757.1\|860890_861991_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	5.2e-24	31.5
WP_004190781.1\|862065_863112_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004196172.1\|863212_864472_+	ABC transporter permease	NA	NA	NA	NA
WP_038802950.1\|865903_867024_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

DBSCAN-SWA_5

1356869 : 1406552

Streptococcus_phage(37.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004191998.1\|1356869_1358333_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004194660.1\|1359048_1359447_-	hypothetical protein	NA	NA	NA	NA
WP_004204055.1\|1359809_1360595_+	enoyl-CoA hydratase	NA	NA	NA	NA
WP_004194608.1\|1360908_1362033_-	alanine racemase	NA	NA	NA	NA
WP_153260196.1\|1362134_1362434_+	hypothetical protein	NA	NA	NA	NA
WP_038716969.1\|1362561_1362942_+	DUF427 domain-containing protein	NA	NA	NA	NA
WP_024900545.1\|1363106_1364342_+	ergothioneine biosynthesis protein EgtB	NA	NA	NA	NA
WP_004194656.1\|1364346_1365321_+	L-histidine N(alpha)-methyltransferase	NA	NA	NA	NA
WP_004204048.1\|1365539_1366028_-	DUF3455 domain-containing protein	NA	NA	NA	NA
WP_004194613.1\|1366317_1367133_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_038802950.1\|1367224_1368345_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004198724.1\|1369366_1371421_-	sugar phosphate isomerase/epimerase and 4-hydroxyphenylpyruvate domain-containing protein	NA	NA	NA	NA
WP_004204041.1\|1371680_1372136_+	type II 3-dehydroquinate dehydratase	NA	NA	NA	NA
WP_004194708.1\|1372132_1372987_+	shikimate dehydrogenase	NA	NA	NA	NA
WP_004194588.1\|1373034_1374381_+	MFS transporter	NA	NA	NA	NA
WP_004194610.1\|1374634_1375744_-	2-aminoethylphosphonate--pyruvate transaminase	NA	NA	NA	NA
WP_004194640.1\|1375981_1377064_+	2-aminoethylphosphonate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004194602.1\|1377120_1378218_+	2-aminoethylphosphonate ABC transport system ATP-binding subunit PhnT	G3M9Y6	Bacillus_virus	5.5e-26	32.5
WP_004194612.1\|1378195_1379143_+	2-aminoethylphosphonate ABC transporter permease subunit	NA	NA	NA	NA
WP_004194685.1\|1379132_1379993_+	2-aminoethylphosphonate ABC transport system, membrane component PhnV	NA	NA	NA	NA
WP_004199121.1\|1380036_1381308_+	phosphonoacetate hydrolase	NA	NA	NA	NA
WP_004194628.1\|1381304_1382759_+	phosphonoacetaldehyde dehydrogenase	NA	NA	NA	NA
WP_004194622.1\|1382763_1383315_+	HD domain-containing protein	A0A2K9L141	Tupanvirus	2.3e-20	34.1
WP_073699529.1\|1383754_1383871_+	phenylacetate-CoA oxygenase	NA	NA	NA	NA
WP_038802950.1\|1389468_1390589_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004199588.1\|1390734_1391145_-	heme-binding protein	NA	NA	NA	NA
WP_004198129.1\|1391204_1392605_-	4Fe-4S binding protein	NA	NA	NA	NA
WP_004198128.1\|1392601_1393444_-	iron transporter OFeT family	NA	NA	NA	NA
WP_004198127.1\|1393503_1393833_-	cupredoxin domain-containing protein	NA	NA	NA	NA
WP_004266710.1\|1393892_1394444_-	membrane protein	NA	NA	NA	NA
WP_004199587.1\|1394667_1396758_-	excinuclease ABC subunit UvrB	NA	NA	NA	NA
WP_004198124.1\|1397045_1398245_+	aspartate/tyrosine/aromatic aminotransferase	NA	NA	NA	NA
WP_004191998.1\|1398403_1399867_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004204588.1\|1400071_1400860_-	3-hydroxybutyrate dehydrogenase	NA	NA	NA	NA
WP_004198121.1\|1401047_1402019_+	NADP-dependent aryl-alcohol dehydrogenase	NA	NA	NA	NA
WP_004198120.1\|1402167_1403013_+	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	NA	NA	NA	NA
WP_004204587.1\|1403025_1403304_-	hypothetical protein	NA	NA	NA	NA
WP_011204222.1\|1403527_1404991_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	2.0e-79	38.3
WP_004198117.1\|1405115_1405262_-	DUF3563 family protein	NA	NA	NA	NA
WP_038802950.1\|1405432_1406552_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP009642

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP009643

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection